# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- 7tm_4 PF13853.6 KFP08745.1 - 4.2e-38 131.7 16.3 5e-38 131.4 16.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08745.1 - 3e-22 79.2 17.2 6.2e-22 78.2 17.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) V-set PF07686.17 KFP08746.1 - 1.5e-08 34.8 0.1 1.6e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain DS PF01916.17 KFP08747.1 - 4.5e-26 91.8 0.0 4.8e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Keratin PF02422.16 KFP08748.1 - 1.1e-39 134.0 10.6 1.2e-39 133.9 10.6 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP08748.1 - 0.11 11.3 0.2 0.12 11.2 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like COesterase PF00135.28 KFP08750.1 - 4.3e-154 514.2 0.0 5.2e-154 513.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP08750.1 - 1.1e-07 31.9 0.0 2.5e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP08750.1 - 0.00063 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family 7tm_4 PF13853.6 KFP08751.1 - 1.5e-18 67.5 3.4 1.7e-18 67.4 3.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08751.1 - 0.023 14.0 2.2 0.033 13.5 2.2 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08752.1 - 4.5e-43 148.0 12.7 5.8e-43 147.6 12.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08752.1 - 6.5e-26 91.2 20.9 3.5e-25 88.8 20.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08754.1 - 1e-47 163.2 14.6 1.2e-47 163.0 14.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08754.1 - 1e-32 113.5 16.2 1.3e-32 113.2 16.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08754.1 - 2.4e-05 23.9 14.6 3.4e-05 23.4 14.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEMspv1-c74-12 PF11044.8 KFP08754.1 - 2.7 8.1 4.0 9.2 6.3 4.0 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein zf-H2C2_2 PF13465.6 KFP08755.1 - 8.7e-20 70.2 14.5 5.9e-10 39.1 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08755.1 - 7.6e-15 54.5 19.5 1.3e-08 34.8 2.7 3.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08755.1 - 3.5e-11 42.9 16.5 1.2e-05 25.7 2.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-AN1 PF01428.16 KFP08755.1 - 3.2e-05 24.0 9.2 0.4 10.9 1.1 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger zf-Di19 PF05605.12 KFP08755.1 - 4.4e-05 23.7 6.6 0.0035 17.6 2.2 2.1 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KFP08755.1 - 0.00028 20.4 12.1 0.035 13.7 0.2 3.2 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP08755.1 - 0.00029 20.9 10.0 0.0014 18.7 3.2 2.6 1 1 0 2 2 2 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFP08755.1 - 0.00052 19.9 17.1 0.011 15.7 1.4 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger DZR PF12773.7 KFP08755.1 - 0.00061 19.8 6.4 0.0062 16.5 6.4 2.1 1 1 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KFP08755.1 - 0.00064 19.6 4.8 0.00064 19.6 4.8 2.2 1 1 1 2 2 2 1 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFP08755.1 - 0.0027 17.6 9.9 0.089 12.7 3.6 3.2 2 1 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP08755.1 - 0.0039 17.4 0.1 0.0039 17.4 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding HypA PF01155.19 KFP08755.1 - 0.004 17.1 2.9 0.02 14.9 3.0 1.8 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 KFP08755.1 - 0.0043 17.1 6.9 0.094 12.8 0.1 2.9 1 1 2 3 3 3 1 CpXC protein zf-C2HC_2 PF13913.6 KFP08755.1 - 0.0055 16.6 12.8 0.0068 16.3 0.3 2.9 3 0 0 3 3 2 2 zinc-finger of a C2HC-type ADK_lid PF05191.14 KFP08755.1 - 0.0058 16.6 5.4 0.12 12.4 1.1 2.4 2 1 0 2 2 2 1 Adenylate kinase, active site lid C1_1 PF00130.22 KFP08755.1 - 0.0066 16.3 5.2 0.02 14.8 1.4 2.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) YhfH PF14149.6 KFP08755.1 - 0.0076 16.2 9.6 1.3 9.0 0.0 3.1 3 0 0 3 3 3 1 YhfH-like protein zinc_ribbon_9 PF14369.6 KFP08755.1 - 0.019 15.2 10.6 0.18 12.1 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon DUF3268 PF11672.8 KFP08755.1 - 0.019 15.3 0.8 0.019 15.3 0.8 1.7 1 1 1 2 2 2 0 zinc-finger-containing domain zf-ribbon_3 PF13248.6 KFP08755.1 - 0.022 14.2 14.4 0.16 11.5 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_7 PF02591.15 KFP08755.1 - 0.025 14.8 8.8 0.38 11.0 0.1 3.2 3 0 0 3 3 3 0 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.5 KFP08755.1 - 0.037 14.8 4.9 0.24 12.2 4.9 1.9 1 1 0 1 1 1 0 zinc-ribbon family zf-HIT PF04438.16 KFP08755.1 - 0.04 13.8 13.8 1.1 9.2 0.3 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-C2H2_8 PF15909.5 KFP08755.1 - 0.041 14.2 2.2 0.088 13.1 0.5 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zinc-ribbons_6 PF07191.12 KFP08755.1 - 0.046 13.7 5.5 1.4 9.0 5.5 2.3 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_10 PF10058.9 KFP08755.1 - 0.071 12.9 5.9 1.2 8.9 2.4 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_2 PF13240.6 KFP08755.1 - 0.078 12.7 16.4 0.82 9.5 1.3 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf-met PF12874.7 KFP08755.1 - 0.1 13.0 0.9 0.1 13.0 0.9 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-UBP PF02148.19 KFP08755.1 - 0.12 12.7 5.1 2 8.8 2.8 2.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein FYDLN_acid PF09538.10 KFP08755.1 - 0.14 12.8 4.8 3.4 8.4 4.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) C1_4 PF07975.12 KFP08755.1 - 0.16 12.3 7.0 4 7.8 2.6 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain PyrI_C PF02748.15 KFP08755.1 - 0.18 11.7 3.2 0.64 10.0 0.1 2.6 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 KFP08755.1 - 0.19 11.8 9.0 0.15 12.2 2.1 2.8 1 1 2 3 3 3 0 BED zinc finger XPA_N PF01286.18 KFP08755.1 - 0.19 11.8 8.9 1.8 8.7 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal IBR PF01485.21 KFP08755.1 - 0.2 11.9 10.1 2.2 8.5 3.5 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 KFP08755.1 - 0.25 11.2 1.5 3.5 7.6 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFP08755.1 - 0.33 11.5 5.6 1.4 9.5 0.1 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Desulfoferrod_N PF06397.12 KFP08755.1 - 0.35 10.5 7.4 1.3 8.7 0.1 2.7 3 0 0 3 3 2 0 Desulfoferrodoxin, N-terminal domain zf-trcl PF13451.6 KFP08755.1 - 0.36 10.8 10.4 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-C2HC5 PF06221.13 KFP08755.1 - 0.37 10.8 7.4 0.31 11.1 1.5 2.7 1 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Cys_rich_CPXG PF14255.6 KFP08755.1 - 0.41 10.6 0.1 0.41 10.6 0.1 2.9 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-C2H2_11 PF16622.5 KFP08755.1 - 0.56 10.0 13.2 0.39 10.5 1.0 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type Terminase_GpA PF05876.12 KFP08755.1 - 0.68 8.4 3.7 0.23 10.0 1.0 1.3 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Nudix_N_2 PF14803.6 KFP08755.1 - 0.68 9.9 12.4 5.8 6.9 6.0 3.6 2 2 0 2 2 2 0 Nudix N-terminal YacG PF03884.14 KFP08755.1 - 0.74 9.6 0.1 0.74 9.6 0.1 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-C2HE PF16278.5 KFP08755.1 - 0.87 10.1 10.4 2.2 8.8 0.4 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Ogr_Delta PF04606.12 KFP08755.1 - 0.89 9.6 12.3 0.3 11.1 3.3 2.5 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger FYVE PF01363.21 KFP08755.1 - 1 9.5 7.0 24 5.2 7.0 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-Mss51 PF13824.6 KFP08755.1 - 1 9.5 12.1 6 7.1 5.6 2.9 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 LIM PF00412.22 KFP08755.1 - 1.1 9.6 6.5 1.5e+02 2.7 7.3 2.8 1 1 0 1 1 1 0 LIM domain Thioredoxin_4 PF13462.6 KFP08755.1 - 1.4 9.1 4.3 0.22 11.7 0.6 1.6 2 0 0 2 2 1 0 Thioredoxin TRAF6_Z2 PF18048.1 KFP08755.1 - 1.4 9.1 6.9 8.2 6.6 1.9 2.6 2 1 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 TF_Zn_Ribbon PF08271.12 KFP08755.1 - 1.5 8.4 9.8 3.5 7.2 0.1 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf-Paramyx-P PF13008.7 KFP08755.1 - 1.7 8.2 8.3 4.7 6.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein zf_C2H2_ZHX PF18387.1 KFP08755.1 - 1.8 8.2 6.1 0.41 10.3 0.8 2.3 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn_Tnp_IS91 PF14319.6 KFP08755.1 - 2 8.5 8.8 6.4 6.9 0.2 2.9 1 1 1 3 3 3 0 Transposase zinc-binding domain Rubredoxin_2 PF18073.1 KFP08755.1 - 2 8.2 15.7 2.2 8.1 0.8 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-LYAR PF08790.11 KFP08755.1 - 2.2 8.3 9.9 6.6 6.7 0.2 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-TFIIB PF13453.6 KFP08755.1 - 2.9 7.3 8.7 4.3 6.7 2.9 2.7 1 1 1 2 2 2 0 Transcription factor zinc-finger DUF35_N PF12172.8 KFP08755.1 - 3.2 7.7 13.6 4 7.4 0.4 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_4 PF13717.6 KFP08755.1 - 3.7 7.5 16.3 0.79 9.7 0.5 3.1 2 1 1 3 3 3 0 zinc-ribbon domain DUF1610 PF07754.11 KFP08755.1 - 4 7.5 11.8 1.9 8.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Ribosomal_L37ae PF01780.19 KFP08755.1 - 4.2 7.5 8.6 12 6.1 0.3 2.9 1 1 2 3 3 3 0 Ribosomal L37ae protein family DUF4379 PF14311.6 KFP08755.1 - 5.6 7.4 7.7 2.4 8.6 2.4 2.4 1 1 0 2 2 2 0 Probable Zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFP08755.1 - 6.1 7.4 9.7 5.5 7.6 4.8 2.6 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain TFIIS_C PF01096.18 KFP08755.1 - 6.2 6.8 13.2 6.4 6.7 0.2 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-H2C2_5 PF13909.6 KFP08755.1 - 6.2 6.7 24.4 0.19 11.5 3.4 4.2 3 2 0 3 3 3 0 C2H2-type zinc-finger domain zf-CCHC_5 PF14787.6 KFP08755.1 - 8.1 6.2 11.4 1.5 8.6 0.3 2.9 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger DUF2256 PF10013.9 KFP08755.1 - 8.4 6.6 10.2 11 6.2 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_5 PF13719.6 KFP08755.1 - 9.4 6.1 15.6 2.4 8.0 4.9 2.9 2 1 0 2 2 2 0 zinc-ribbon domain HSA PF07529.13 KFP08756.1 - 2.5e-19 69.3 6.5 2.5e-19 69.3 6.5 1.4 2 0 0 2 2 2 1 HSA DBINO PF13892.6 KFP08756.1 - 2.1e-05 24.9 9.1 2.6e-05 24.6 9.1 1.1 1 0 0 1 1 1 1 DNA-binding domain CR6_interact PF10147.9 KFP08756.1 - 0.0098 15.6 6.9 0.012 15.4 6.9 1.0 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Cas_Csy4 PF09618.10 KFP08756.1 - 0.02 15.0 2.6 0.023 14.9 2.6 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) SCO1-SenC PF02630.14 KFP08756.1 - 0.1 12.5 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 SCO1/SenC DUF3332 PF11810.8 KFP08756.1 - 0.11 12.1 2.3 0.13 11.9 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) FAM27 PF15832.5 KFP08756.1 - 0.21 12.1 4.1 0.2 12.2 3.3 1.4 1 1 0 1 1 1 0 FAM27 D and E protein family Fib_alpha PF08702.10 KFP08756.1 - 0.37 11.0 5.3 0.46 10.7 5.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CorA PF01544.18 KFP08756.1 - 0.7 9.1 4.0 0.76 9.0 4.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein 7tm_4 PF13853.6 KFP08757.1 - 1.7e-12 47.7 1.1 2e-12 47.4 1.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08757.1 - 2.8e-08 33.4 1.2 3.6e-08 33.0 1.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08758.1 - 1.2e-32 113.8 7.5 1.4e-32 113.6 7.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08758.1 - 8.9e-19 67.8 13.0 1.3e-18 67.3 13.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) L6_membrane PF05805.12 KFP08758.1 - 0.013 15.1 5.5 0.025 14.2 5.5 1.4 1 0 0 1 1 1 0 L6 membrane protein TMEMspv1-c74-12 PF11044.8 KFP08758.1 - 0.63 10.1 5.2 1.5 8.8 5.2 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein 7tm_4 PF13853.6 KFP08759.1 - 3.8e-17 62.9 2.0 4.3e-17 62.8 2.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08759.1 - 0.0082 15.5 2.9 0.0099 15.2 2.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08760.1 - 4.8e-18 65.9 1.6 5.2e-18 65.8 1.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08760.1 - 0.00094 18.6 2.4 0.0011 18.3 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Homeodomain PF00046.29 KFP08761.1 - 3.1e-14 52.6 2.0 3.4e-14 52.4 2.0 1.0 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFP08761.1 - 0.0016 18.7 0.1 0.0017 18.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) zf-C2H2 PF00096.26 KFP08762.1 - 1.9e-12 46.9 14.8 5.6e-06 26.5 1.9 3.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP08762.1 - 1e-11 44.7 7.0 5.3e-07 29.8 0.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFP08762.1 - 1.3e-06 28.2 11.8 0.00027 20.9 0.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFP08762.1 - 2.4e-06 27.9 12.8 0.0096 16.7 1.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP08762.1 - 5.2e-05 23.5 7.5 0.34 11.4 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP08762.1 - 0.00035 20.8 5.7 1.2 9.6 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP08762.1 - 0.00045 19.8 4.1 2.4 7.8 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 KFP08762.1 - 0.0021 17.9 0.2 0.0036 17.1 0.2 1.5 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KFP08762.1 - 0.0081 16.3 5.4 1.3 9.2 0.4 2.6 2 1 1 3 3 3 3 Zinc ribbon domain HalOD2 PF18547.1 KFP08762.1 - 0.0085 16.0 1.0 0.021 14.7 1.0 1.7 1 1 0 1 1 1 1 Halobacterial output domain 2 Desulfoferrod_N PF06397.12 KFP08762.1 - 0.012 15.2 4.3 0.057 13.0 0.5 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF3268 PF11672.8 KFP08762.1 - 0.015 15.6 0.5 0.019 15.3 0.5 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain XPA_N PF01286.18 KFP08762.1 - 0.021 14.9 4.5 2.6 8.2 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal FAM209 PF15206.6 KFP08762.1 - 0.023 14.5 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 FAM209 family HypA PF01155.19 KFP08762.1 - 0.034 14.2 1.1 0.037 14.1 1.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2256 PF10013.9 KFP08762.1 - 0.042 14.0 1.9 0.61 10.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-AN1 PF01428.16 KFP08762.1 - 0.043 14.0 3.9 1.8 8.8 0.1 2.6 3 0 0 3 3 3 0 AN1-like Zinc finger zf-HIT PF04438.16 KFP08762.1 - 0.044 13.7 3.0 0.89 9.5 0.5 2.3 2 0 0 2 2 2 0 HIT zinc finger C1_4 PF07975.12 KFP08762.1 - 0.046 14.0 2.4 0.53 10.6 1.9 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 KFP08762.1 - 0.05 13.5 11.3 2.9 7.9 1.4 3.5 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf-Sec23_Sec24 PF04810.15 KFP08762.1 - 0.16 12.0 2.1 5 7.3 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zinc_ribbon_4 PF13717.6 KFP08762.1 - 0.24 11.4 4.8 4.1 7.4 1.1 2.6 1 1 1 2 2 2 0 zinc-ribbon domain FYVE PF01363.21 KFP08762.1 - 0.56 10.4 5.7 3.8 7.7 5.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.15 KFP08762.1 - 0.69 10.0 7.0 4.5 7.4 0.6 2.5 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 KFP08762.1 - 9 6.2 10.5 7.9 6.3 0.6 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type UPF0542 PF15086.6 KFP08763.1 - 1.1e-31 108.5 3.0 1.2e-31 108.4 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 TMEM100 PF16311.5 KFP08763.1 - 0.061 12.9 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 7tm_1 PF00001.21 KFP08763.1 - 0.17 11.2 0.0 0.17 11.2 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PDEase_I PF00233.19 KFP08764.1 - 3.5e-06 26.9 0.0 4e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-H2C2_2 PF13465.6 KFP08765.1 - 1.9e-14 53.3 2.2 1.3e-07 31.7 0.2 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP08765.1 - 8.8e-07 29.0 1.9 8.8e-07 29.0 1.9 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08765.1 - 0.0011 19.6 1.3 0.0011 19.6 1.3 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KFP08765.1 - 0.0079 16.6 0.7 0.012 16.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP08765.1 - 0.013 15.8 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP08765.1 - 0.014 15.3 1.2 0.022 14.7 1.2 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KFP08765.1 - 0.7 9.7 3.7 0.9 9.4 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DnaJ PF00226.31 KFP08766.1 - 5e-06 26.5 0.1 6.1e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain Cullin_Nedd8 PF10557.9 KFP08767.1 - 9.1e-09 35.2 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Keratin PF02422.16 KFP08768.1 - 7.5e-38 128.1 9.6 8.3e-38 128.0 9.6 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.17 KFP08768.1 - 0.087 13.1 5.6 0.11 12.8 5.6 1.1 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain CENP-T_C PF15511.6 KFP08769.1 - 1.6e-08 34.6 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFP08769.1 - 2.2e-05 24.5 0.2 3.2e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFP08769.1 - 4.2e-05 23.8 0.1 5.5e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFP08769.1 - 0.00016 22.0 0.3 0.00018 21.9 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP08769.1 - 0.00025 21.3 0.1 0.00042 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP08769.1 - 0.0054 16.8 0.0 0.0061 16.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFP08769.1 - 0.022 14.7 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFP08769.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) zf-C2H2 PF00096.26 KFP08772.1 - 6.5e-10 38.9 7.0 1e-05 25.7 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP08772.1 - 5.2e-07 29.8 1.0 5.2e-07 29.8 1.0 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08772.1 - 1.3e-05 25.6 6.6 0.02 15.7 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFP08772.1 - 0.00013 21.5 0.5 0.32 10.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 KFP08772.1 - 0.00068 19.5 2.1 0.61 10.0 0.1 2.3 2 1 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KFP08772.1 - 0.001 19.0 5.8 0.12 12.4 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP08772.1 - 0.0019 18.2 2.1 0.13 12.4 0.1 2.1 2 0 0 2 2 2 1 Zinc ribbon domain DZR PF12773.7 KFP08772.1 - 0.0027 17.7 0.6 0.0029 17.6 0.6 1.1 1 0 0 1 1 1 1 Double zinc ribbon Zn_ribbon_recom PF13408.6 KFP08772.1 - 0.003 18.0 2.3 0.05 14.1 2.6 2.0 1 1 1 2 2 2 1 Recombinase zinc beta ribbon domain XPA_N PF01286.18 KFP08772.1 - 0.0056 16.7 1.3 1.7 8.8 0.1 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-trcl PF13451.6 KFP08772.1 - 0.013 15.4 2.3 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFP08772.1 - 0.014 15.3 2.2 0.063 13.2 2.2 1.9 1 1 0 1 1 1 0 SprT-like zinc ribbon domain C1_1 PF00130.22 KFP08772.1 - 0.017 15.0 1.3 0.18 11.7 0.4 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.8 KFP08772.1 - 0.017 15.4 1.7 0.91 9.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.13 KFP08772.1 - 0.017 14.8 3.1 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Endonuclease_7 PF02945.15 KFP08772.1 - 0.034 14.1 1.3 0.036 14.0 1.3 1.1 1 0 0 1 1 1 0 Recombination endonuclease VII zinc_ribbon_15 PF17032.5 KFP08772.1 - 0.036 14.8 0.4 0.037 14.8 0.4 1.0 1 0 0 1 1 1 0 zinc-ribbon family CpXC PF14353.6 KFP08772.1 - 0.047 13.7 0.5 6.4 6.9 0.1 2.0 2 0 0 2 2 2 0 CpXC protein RNA_POL_M_15KD PF02150.16 KFP08772.1 - 0.047 13.6 0.2 0.1 12.5 0.2 1.7 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zinc_ribbon_5 PF13719.6 KFP08772.1 - 0.051 13.3 0.9 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.9 KFP08772.1 - 0.095 12.8 1.5 0.41 10.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 KFP08772.1 - 0.1 13.0 1.0 0.24 11.9 0.4 1.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger YhfH PF14149.6 KFP08772.1 - 0.13 12.2 2.0 7.8 6.6 0.2 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2_11 PF16622.5 KFP08772.1 - 0.17 11.7 3.9 0.33 10.8 0.3 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 KFP08772.1 - 0.18 11.8 1.7 4 7.5 1.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KFP08772.1 - 0.63 9.8 6.7 0.45 10.3 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-AN1 PF01428.16 KFP08772.1 - 4.8 7.4 7.8 24 5.2 4.5 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger Ets PF00178.22 KFP08773.1 - 3.7e-24 85.0 0.2 4.1e-24 84.8 0.2 1.0 1 0 0 1 1 1 1 Ets-domain UDPGT PF00201.18 KFP08774.1 - 1.2e-26 93.6 0.0 1.3e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-H2C2_2 PF13465.6 KFP08775.1 - 5.2e-09 36.1 8.8 0.0003 21.1 0.6 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08775.1 - 1.4e-07 31.7 10.4 0.0024 18.6 1.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP08775.1 - 4e-06 27.0 11.4 0.011 16.2 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP08775.1 - 2e-05 24.4 8.9 0.02 14.9 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP08775.1 - 0.00061 20.1 7.2 0.043 14.2 0.5 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP08775.1 - 0.0011 19.2 2.0 0.0011 19.2 2.0 2.9 2 1 0 2 2 2 1 Zinc-finger of C2H2 type PHD_4 PF16866.5 KFP08775.1 - 0.0014 18.7 1.3 0.0018 18.4 1.3 1.2 1 0 0 1 1 1 1 PHD-finger Fer4_8 PF13183.6 KFP08775.1 - 0.013 16.0 1.4 0.028 14.9 0.3 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-MYST PF17772.1 KFP08775.1 - 0.029 14.0 0.5 0.029 14.0 0.5 2.5 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2HE PF16278.5 KFP08775.1 - 0.084 13.3 6.4 1.6 9.3 0.6 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFP08775.1 - 0.14 12.5 0.5 0.14 12.5 0.5 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 KFP08775.1 - 0.84 9.9 5.0 6.4 7.0 0.4 2.0 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Ras PF00071.22 KFP08776.1 - 2.2e-40 137.9 0.0 2.4e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08776.1 - 4.1e-10 39.9 0.0 5.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP08776.1 - 1.1e-05 25.1 0.0 4.4e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFP08776.1 - 2.6e-05 23.7 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP08776.1 - 0.0024 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFP08776.1 - 0.0068 16.4 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFP08776.1 - 0.03 13.9 0.0 0.032 13.8 0.0 1.3 1 1 0 1 1 1 0 Ferrous iron transport protein B Keratin PF02422.16 KFP08777.1 - 5.9e-34 115.6 7.4 5.9e-34 115.6 7.4 2.0 1 1 1 2 2 2 1 Keratin DUF35_N PF12172.8 KFP08777.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3432 PF11914.8 KFP08777.1 - 0.11 12.7 5.6 0.17 12.2 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Sulfotransfer_1 PF00685.27 KFP08778.1 - 1.2e-30 107.0 0.0 1.5e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP08778.1 - 9.3e-10 39.2 0.0 1.4e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP08778.1 - 0.012 15.5 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family IL8 PF00048.20 KFP08779.1 - 3e-06 27.3 0.1 3.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like COesterase PF00135.28 KFP08781.1 - 2.4e-50 171.9 0.0 2.6e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Filament PF00038.21 KFP08782.1 - 2.8e-49 168.4 6.6 3.1e-49 168.2 6.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF5344 PF17279.2 KFP08782.1 - 0.001 19.6 3.1 0.26 11.9 2.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5344) Leu_zip PF15294.6 KFP08782.1 - 0.0019 17.8 3.2 0.0027 17.3 3.2 1.3 1 0 0 1 1 1 1 Leucine zipper Bacillus_HBL PF05791.11 KFP08782.1 - 0.0022 17.9 3.5 0.0029 17.5 3.0 1.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Sec2p PF06428.11 KFP08782.1 - 0.0067 16.4 7.7 0.047 13.7 0.5 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 KFP08782.1 - 0.019 14.3 6.7 0.028 13.8 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Transcrip_act PF04949.13 KFP08782.1 - 0.021 14.7 1.3 0.36 10.7 0.3 2.2 1 1 0 2 2 2 0 Transcriptional activator Prefoldin PF02996.17 KFP08782.1 - 0.021 14.7 7.1 1.4 8.8 0.8 3.0 2 1 1 3 3 3 0 Prefoldin subunit Lzipper-MIP1 PF14389.6 KFP08782.1 - 0.024 14.9 1.2 0.024 14.9 1.2 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4924 PF16271.5 KFP08782.1 - 0.029 14.4 0.9 0.047 13.7 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4924) FapA PF03961.13 KFP08782.1 - 0.031 12.9 2.0 0.041 12.5 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 KFP08782.1 - 0.044 13.8 5.2 1.1 9.3 5.2 2.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 KFP08782.1 - 0.11 12.6 7.2 0.14 12.3 7.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 KFP08782.1 - 0.12 12.4 12.3 1.2 9.2 12.1 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFP08782.1 - 0.23 10.5 5.7 0.31 10.1 5.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KFP08782.1 - 0.24 11.6 6.6 3 8.0 1.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP08782.1 - 0.3 11.1 3.6 0.86 9.7 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KFP08782.1 - 0.31 11.1 11.0 1.6 8.8 1.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KFP08782.1 - 0.45 11.2 13.9 2.1 9.0 2.7 3.1 2 1 1 3 3 3 0 SlyX SOGA PF11365.8 KFP08782.1 - 0.47 11.6 6.5 0.62 11.2 1.5 2.2 1 1 1 2 2 2 0 Protein SOGA Csm1_N PF18504.1 KFP08782.1 - 0.57 10.6 12.0 0.41 11.0 1.3 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain Med9 PF07544.13 KFP08782.1 - 0.81 9.8 5.8 0.98 9.6 0.2 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HIP1_clath_bdg PF16515.5 KFP08782.1 - 1.4 9.6 11.7 0.78 10.4 7.3 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Jnk-SapK_ap_N PF09744.9 KFP08782.1 - 1.4 9.1 10.5 0.59 10.3 6.2 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 KFP08782.1 - 2.1 8.9 6.7 1e+02 3.4 6.7 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KFP08782.1 - 2.2 8.7 6.6 22 5.5 2.0 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) COMP PF11598.8 KFP08782.1 - 2.7 8.5 8.8 16 6.1 1.4 3.6 3 1 0 3 3 3 0 Cartilage oligomeric matrix protein FlxA PF14282.6 KFP08782.1 - 2.9 7.9 11.7 1.6 8.7 7.9 2.2 1 1 1 2 2 2 0 FlxA-like protein HalX PF08663.10 KFP08782.1 - 3.8 7.9 11.9 0.33 11.3 1.7 3.0 1 1 2 3 3 3 0 HalX domain APG6_N PF17675.1 KFP08782.1 - 6 7.4 13.0 9.1 6.8 13.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region LAP1C PF05609.12 KFP08783.1 - 1.2e-102 344.3 0.2 1.4e-102 344.2 0.2 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Stap_Strp_tox_C PF02876.17 KFP08783.1 - 0.03 14.6 0.0 0.074 13.4 0.0 1.6 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Defensin_beta PF00711.19 KFP08784.1 - 4.3e-08 33.0 10.9 5.6e-08 32.7 10.9 1.2 1 0 0 1 1 1 1 Beta defensin HSP70 PF00012.20 KFP08785.1 - 2.5e-10 39.2 0.1 7.4e-06 24.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Keratin PF02422.16 KFP08786.1 - 5.2e-31 106.2 12.0 5.6e-31 106.1 12.0 1.0 1 0 0 1 1 1 1 Keratin Sushi PF00084.20 KFP08787.1 - 2.3e-16 60.1 3.9 3.9e-11 43.4 0.8 2.0 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Kelch_1 PF01344.25 KFP08788.1 - 1.3e-27 95.1 4.6 9.9e-09 34.6 0.0 3.3 3 0 0 3 3 3 3 Kelch motif BACK PF07707.15 KFP08788.1 - 6.8e-26 90.4 3.0 6.8e-26 90.4 3.0 2.5 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 KFP08788.1 - 1.3e-22 80.1 1.2 2.3e-22 79.3 1.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP08788.1 - 2.5e-18 65.6 1.4 3e-05 24.1 0.0 3.4 1 1 2 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KFP08788.1 - 6.6e-14 51.7 0.1 0.0016 18.4 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP08788.1 - 2.6e-10 39.9 5.1 0.0006 19.7 0.1 4.1 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KFP08788.1 - 1.6e-07 31.5 1.2 0.0011 19.2 0.1 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP08788.1 - 3.7e-06 26.8 3.9 0.059 13.4 0.4 3.3 3 0 0 3 3 3 2 Kelch motif Filament PF00038.21 KFP08789.1 - 9e-37 127.3 11.9 9.9e-37 127.2 11.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein Lzipper-MIP1 PF14389.6 KFP08789.1 - 0.00062 20.0 3.9 0.0014 18.9 3.9 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Baculo_PEP_C PF04513.12 KFP08789.1 - 0.00095 19.2 7.8 0.0043 17.1 7.8 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KFP08789.1 - 0.0015 19.1 12.3 0.21 12.2 4.7 3.1 1 1 2 3 3 3 2 SlyX T2SSM PF04612.12 KFP08789.1 - 0.0033 17.5 4.8 0.97 9.5 3.0 2.1 1 1 0 2 2 2 1 Type II secretion system (T2SS), protein M SKA1 PF07160.12 KFP08789.1 - 0.0047 16.8 5.3 0.0047 16.8 5.3 1.6 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Prominin PF05478.11 KFP08789.1 - 0.0067 14.5 4.6 0.007 14.4 4.6 1.0 1 0 0 1 1 1 1 Prominin Exonuc_VII_L PF02601.15 KFP08789.1 - 0.0081 15.8 4.9 0.0096 15.5 4.9 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit Flagellar_rod PF05149.12 KFP08789.1 - 0.0093 15.5 5.9 0.012 15.1 5.9 1.1 1 0 0 1 1 1 1 Paraflagellar rod protein Gp58 PF07902.11 KFP08789.1 - 0.0095 14.3 2.6 0.012 14.0 2.6 1.2 1 0 0 1 1 1 1 gp58-like protein DUF812 PF05667.11 KFP08789.1 - 0.012 14.5 9.0 0.013 14.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cytochrom_B562 PF07361.11 KFP08789.1 - 0.012 16.2 1.2 0.21 12.2 0.4 2.2 1 1 1 2 2 2 0 Cytochrome b562 Spc7 PF08317.11 KFP08789.1 - 0.014 14.3 13.7 0.021 13.7 13.7 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KFP08789.1 - 0.016 15.0 5.7 0.049 13.5 2.8 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Sec2p PF06428.11 KFP08789.1 - 0.018 15.0 4.7 0.018 15.0 4.7 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Phage_GPO PF05929.11 KFP08789.1 - 0.019 14.6 3.7 0.022 14.4 3.7 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 KFP08789.1 - 0.027 14.7 8.7 0.036 14.2 8.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 KFP08789.1 - 0.03 14.3 15.1 0.27 11.3 11.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Nsp1_C PF05064.13 KFP08789.1 - 0.033 14.0 8.7 0.042 13.6 8.7 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region SH3BP5 PF05276.14 KFP08789.1 - 0.034 13.9 6.6 1.4 8.6 0.2 2.1 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Peptidase_M2 PF01401.18 KFP08789.1 - 0.035 12.7 2.5 0.038 12.6 2.5 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF1664 PF07889.12 KFP08789.1 - 0.044 13.8 7.6 0.19 11.8 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 KFP08789.1 - 0.046 14.1 8.8 0.06 13.7 7.1 1.8 1 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Transposase_22 PF02994.14 KFP08789.1 - 0.062 13.5 0.7 0.086 13.0 0.7 1.3 1 0 0 1 1 1 0 L1 transposable element RBD-like domain FAM76 PF16046.5 KFP08789.1 - 0.065 12.6 2.7 0.076 12.4 2.7 1.1 1 0 0 1 1 1 0 FAM76 protein Tup_N PF08581.10 KFP08789.1 - 0.066 13.5 12.9 0.32 11.3 4.0 2.6 1 1 0 2 2 2 0 Tup N-terminal Tox-ODYAM1 PF15642.6 KFP08789.1 - 0.069 12.1 3.3 0.078 11.9 3.3 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Golgin_A5 PF09787.9 KFP08789.1 - 0.071 12.6 12.8 0.12 11.8 12.8 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KFP08789.1 - 0.077 13.2 13.8 0.17 12.1 13.8 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SLATT_5 PF18160.1 KFP08789.1 - 0.081 12.2 4.5 0.27 10.5 1.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF16 PF01519.16 KFP08789.1 - 0.083 13.4 9.5 0.072 13.6 7.8 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 TMPIT PF07851.13 KFP08789.1 - 0.083 12.1 6.7 0.1 11.8 6.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein CC2-LZ PF16516.5 KFP08789.1 - 0.084 13.3 6.1 0.086 13.2 2.7 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YlqD PF11068.8 KFP08789.1 - 0.085 13.2 11.9 0.67 10.3 7.6 2.2 1 1 0 2 2 2 0 YlqD protein CENP-F_leu_zip PF10473.9 KFP08789.1 - 0.087 12.9 14.1 0.39 10.7 14.2 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tho2 PF11262.8 KFP08789.1 - 0.091 12.0 6.2 0.11 11.7 6.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF5344 PF17279.2 KFP08789.1 - 0.091 13.4 10.4 1.4 9.5 2.6 2.8 1 1 2 3 3 2 0 Family of unknown function (DUF5344) HMMR_N PF15905.5 KFP08789.1 - 0.095 12.2 10.4 0.11 11.9 10.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KFP08789.1 - 0.12 11.7 11.0 0.36 10.1 11.1 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 KFP08789.1 - 0.15 11.9 5.5 0.21 11.4 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 KFP08789.1 - 0.15 12.0 7.8 0.26 11.3 7.8 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF2564 PF10819.8 KFP08789.1 - 0.17 12.3 0.4 0.17 12.3 0.4 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2564) Phage_GP20 PF06810.11 KFP08789.1 - 0.17 11.7 5.0 0.24 11.2 4.2 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KFP08789.1 - 0.18 11.9 14.3 0.92 9.6 14.4 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 KFP08789.1 - 0.18 11.7 10.1 0.54 10.1 10.1 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prefoldin PF02996.17 KFP08789.1 - 0.2 11.6 8.3 0.13 12.1 2.1 2.9 1 1 1 3 3 3 0 Prefoldin subunit ZYG-11_interact PF05884.12 KFP08789.1 - 0.21 11.0 1.5 0.21 10.9 1.5 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 UPF0242 PF06785.11 KFP08789.1 - 0.22 11.6 10.7 0.27 11.3 10.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KFP08789.1 - 0.22 10.6 10.3 0.27 10.3 10.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SLATT_6 PF18169.1 KFP08789.1 - 0.24 11.0 3.4 1.4 8.5 3.0 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 DUF948 PF06103.11 KFP08789.1 - 0.24 11.7 4.3 8.6 6.7 4.3 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 KFP08789.1 - 0.29 9.6 1.0 0.33 9.4 1.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tweety PF04906.13 KFP08789.1 - 0.3 9.7 3.5 0.3 9.7 2.5 1.4 1 1 0 1 1 1 0 Tweety Mod_r PF07200.13 KFP08789.1 - 0.44 10.6 12.4 1.2 9.2 12.4 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 KFP08789.1 - 0.45 10.6 12.4 1.1 9.4 12.4 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.6 KFP08789.1 - 0.46 10.7 13.1 0.55 10.4 8.0 2.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.20 KFP08789.1 - 0.62 10.0 14.1 0.53 10.3 4.4 3.1 1 1 2 3 3 3 0 Prefoldin subunit ABC_tran_CTD PF16326.5 KFP08789.1 - 0.67 10.2 14.0 1.6 9.0 5.3 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF4407 PF14362.6 KFP08789.1 - 0.69 9.2 5.8 1.2 8.4 5.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 KFP08789.1 - 0.84 10.1 8.6 1 9.8 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Fungal_TACC PF12709.7 KFP08789.1 - 0.95 9.9 8.1 2.3 8.7 4.7 2.7 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins AI-2E_transport PF01594.16 KFP08789.1 - 1.1 8.4 2.0 1.2 8.2 0.9 1.6 1 1 1 2 2 2 0 AI-2E family transporter DUF4140 PF13600.6 KFP08789.1 - 1.1 9.7 9.1 11 6.6 6.7 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KFP08789.1 - 1.3 9.6 14.8 3.9 8.0 14.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KFP08789.1 - 1.5 9.2 11.6 3.3 8.2 2.5 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 KFP08789.1 - 1.6 9.5 6.3 2.3 9.0 3.7 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) KELK PF15796.5 KFP08789.1 - 2.1 8.9 10.2 0.28 11.6 4.2 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HIP1_clath_bdg PF16515.5 KFP08789.1 - 2.1 9.0 13.8 13 6.5 13.8 2.2 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NPV_P10 PF05531.12 KFP08789.1 - 2.9 8.4 7.6 16 6.1 5.2 2.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KFP08789.1 - 2.9 8.6 10.7 18 6.0 5.7 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Wbp11 PF09429.10 KFP08789.1 - 5.5 7.5 7.8 12 6.3 5.2 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 DUF745 PF05335.13 KFP08789.1 - 6.8 6.4 8.5 9.9 5.8 7.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Sulfotransfer_1 PF00685.27 KFP08791.1 - 7.1e-75 251.9 0.0 8e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP08791.1 - 0.0027 18.1 0.3 0.0057 17.1 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family TLV_coat PF00429.19 KFP08792.1 - 4.3e-109 365.7 1.0 4.8e-109 365.6 1.0 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) PSII_Ycf12 PF05969.11 KFP08792.1 - 0.013 15.4 1.1 0.035 14.1 1.1 1.7 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 SlyX PF04102.12 KFP08792.1 - 0.2 12.3 1.9 0.36 11.5 0.1 2.3 2 1 1 3 3 3 0 SlyX Ribosomal_L21e PF01157.18 KFP08793.1 - 8.9e-29 99.3 6.2 8.9e-29 99.3 6.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Nudix_hydro PF18290.1 KFP08793.1 - 0.0043 17.0 1.3 0.0065 16.4 1.3 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain CLP_protease PF00574.23 KFP08793.1 - 0.011 15.7 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Clp protease YycC PF14174.6 KFP08793.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 YycC-like protein V-set PF07686.17 KFP08794.1 - 3.5e-06 27.1 0.3 4.1e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP08794.1 - 0.15 12.7 0.1 0.18 12.4 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Trypsin PF00089.26 KFP08795.1 - 9.9e-61 205.4 1.0 1.1e-60 205.2 1.0 1.0 1 0 0 1 1 1 1 Trypsin Plavaka PF18759.1 KFP08796.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Plavaka transposase Pkinase PF00069.25 KFP08797.1 - 1.1e-35 123.3 0.0 1.4e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08797.1 - 2.2e-08 33.7 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Serpin PF00079.20 KFP08798.1 - 1.2e-94 317.7 6.9 1.3e-94 317.6 6.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Cytochrom_B_N_2 PF13631.6 KFP08799.1 - 0.004 17.2 0.0 0.004 17.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB 7tm_4 PF13853.6 KFP08800.1 - 3.6e-39 135.2 13.9 4.2e-39 134.9 13.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08800.1 - 1.6e-28 99.8 14.5 2.1e-28 99.4 14.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08800.1 - 0.00041 19.8 12.3 0.00061 19.2 12.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP08800.1 - 0.038 13.6 13.7 0.074 12.7 13.7 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP08801.1 - 9.1e-45 153.5 11.3 1e-44 153.4 11.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08801.1 - 5.5e-26 91.5 14.4 6.8e-26 91.2 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08801.1 - 0.082 12.3 9.6 0.09 12.1 8.9 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx TMEMspv1-c74-12 PF11044.8 KFP08801.1 - 3.3 7.8 9.0 0.58 10.2 3.1 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein 7tm_4 PF13853.6 KFP08802.1 - 3.7e-44 151.5 6.0 4.3e-44 151.3 6.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08802.1 - 1.4e-25 90.1 10.7 2.2e-25 89.5 10.7 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08803.1 - 4.4e-52 177.5 11.6 5.2e-52 177.3 11.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08803.1 - 6.1e-32 111.0 16.7 8.2e-32 110.6 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08803.1 - 0.00032 20.2 13.3 0.00032 20.2 13.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP08804.1 - 7.8e-41 140.6 14.7 9.2e-41 140.4 14.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08804.1 - 1.6e-24 86.7 22.8 5e-24 85.0 22.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP08805.1 - 5.9e-47 160.7 10.1 7e-47 160.5 10.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP08805.1 - 1.2e-28 100.2 15.6 2.3e-28 99.2 15.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP08805.1 - 0.023 14.4 11.1 0.047 13.3 10.8 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Laminin_G_2 PF02210.24 KFP08807.1 - 8.5e-46 155.6 0.1 3.9e-23 82.4 0.1 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP08807.1 - 7.4e-30 103.8 0.0 9.5e-14 51.7 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 KFP08807.1 - 0.00017 21.8 0.0 0.00074 19.7 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.20 KFP08807.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain hEGF PF12661.7 KFP08807.1 - 0.019 15.6 6.4 0.019 15.6 6.4 2.9 3 0 0 3 3 3 0 Human growth factor-like EGF MARVEL PF01284.23 KFP08807.1 - 0.087 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Membrane-associating domain PRC2_HTH_1 PF18118.1 KFP08810.1 - 2.1e-31 108.7 3.0 2.1e-31 108.7 3.0 2.7 2 0 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain SET PF00856.28 KFP08810.1 - 3.2e-18 66.7 6.0 6.5e-18 65.7 0.5 3.0 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.8 KFP08810.1 - 3e-16 59.2 3.5 7.3e-16 58.0 3.5 1.7 1 0 0 1 1 1 1 WD repeat binding protein EZH2 preSET_CXC PF18264.1 KFP08810.1 - 4.8e-12 46.1 15.6 4.8e-12 46.1 15.6 3.9 2 1 0 2 2 2 1 CXC domain Thioredoxin PF00085.20 KFP08813.1 - 8.4e-98 321.2 0.7 3.3e-32 110.5 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KFP08813.1 - 2.5e-24 86.2 7.5 7e-17 61.9 0.5 4.6 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP08813.1 - 1.5e-17 63.7 1.3 0.0024 18.2 0.0 6.5 4 2 2 6 6 6 3 Thioredoxin-like OST3_OST6 PF04756.13 KFP08813.1 - 3.8e-16 59.3 0.0 2.3e-05 23.9 0.0 3.2 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP08813.1 - 4.9e-16 59.1 1.1 0.0013 19.2 0.0 4.4 3 1 0 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KFP08813.1 - 8.5e-12 44.8 0.1 8.5e-12 44.8 0.1 2.9 3 0 0 3 3 2 2 Calsequestrin Thioredoxin_7 PF13899.6 KFP08813.1 - 8.6e-12 45.1 0.0 0.029 14.6 0.0 3.7 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.21 KFP08813.1 - 1.6e-09 37.7 0.1 0.067 13.1 0.0 3.9 3 0 0 3 3 3 3 AhpC/TSA family TraF PF13728.6 KFP08813.1 - 2.4e-07 30.8 0.0 0.066 13.0 0.0 3.4 3 0 0 3 3 3 3 F plasmid transfer operon protein Redoxin PF08534.10 KFP08813.1 - 5.8e-06 26.1 0.7 0.76 9.5 0.0 3.9 4 0 0 4 4 4 3 Redoxin Thioredoxin_4 PF13462.6 KFP08813.1 - 7.4e-06 26.2 1.8 4.2 7.5 0.0 4.4 4 0 0 4 4 4 3 Thioredoxin HyaE PF07449.11 KFP08813.1 - 0.00028 20.8 0.0 4.1 7.4 0.0 3.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFP08813.1 - 0.00097 18.9 0.1 3.4 7.4 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.6 KFP08813.1 - 0.0025 17.8 0.0 6.2 6.9 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain DUF836 PF05768.14 KFP08813.1 - 0.007 16.8 0.0 8.4 6.9 0.0 3.6 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KFP08813.1 - 0.077 12.8 1.7 36 4.1 0.1 4.6 3 3 3 6 6 6 0 DSBA-like thioredoxin domain DUF953 PF06110.11 KFP08813.1 - 0.14 11.7 0.5 8.4 6.1 0.0 3.4 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF953) THB PF18362.1 KFP08813.1 - 0.15 11.7 1.1 7.6 6.2 0.1 3.3 3 0 0 3 3 3 0 Tri-helix bundle domain Thioredoxin_5 PF13743.6 KFP08813.1 - 0.82 9.3 5.5 34 4.0 0.2 4.5 3 2 2 5 5 5 0 Thioredoxin Pkinase_Tyr PF07714.17 KFP08814.1 - 2.5e-97 325.2 0.0 3.9e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP08814.1 - 7.5e-47 159.9 0.0 1.4e-46 159.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.10 KFP08814.1 - 6.7e-28 97.0 0.1 1.4e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.24 KFP08814.1 - 2.2e-24 85.4 0.2 5.1e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP08814.1 - 3.6e-12 45.7 0.0 6.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP08814.1 - 4.9e-07 29.5 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP08814.1 - 5.3e-07 29.2 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP08814.1 - 3e-05 24.2 0.6 9.2e-05 22.6 0.6 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFP08814.1 - 0.0035 16.3 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RGS12_us1 PF16613.5 KFP08814.1 - 0.032 14.5 2.7 0.12 12.7 2.7 2.0 1 0 0 1 1 1 0 Unstructured region of RGS12 SH3_6 PF12913.7 KFP08814.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) GRP PF07172.11 KFP08814.1 - 0.15 12.7 2.0 0.51 11.0 2.0 1.8 1 0 0 1 1 1 0 Glycine rich protein family Fam20C PF06702.12 KFP08815.1 - 7.2e-87 290.8 0.0 1e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFP08815.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein RasGEF PF00617.19 KFP08816.1 - 4.8e-53 180.0 0.2 1.5e-52 178.4 0.1 1.8 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 KFP08816.1 - 1.2e-09 38.6 0.1 3.1e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 PH domain CRISPR_Cas9_WED PF18061.1 KFP08816.1 - 0.012 15.7 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain Fibrinogen_C PF00147.18 KFP08817.1 - 4.4e-73 245.7 10.3 5.9e-73 245.3 10.3 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain ZirS_C PF16583.5 KFP08817.1 - 0.011 15.4 0.2 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain SlyX PF04102.12 KFP08817.1 - 1.5 9.5 5.5 6.5 7.5 0.6 2.9 1 1 1 3 3 3 0 SlyX ETS_PEA3_N PF04621.13 KFP08820.1 - 1.5e-140 469.0 20.8 2.3e-140 468.4 20.8 1.3 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFP08820.1 - 2.1e-38 130.6 0.2 3.6e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 Ets-domain DAGK_acc PF00609.19 KFP08821.1 - 8.9e-56 188.6 0.0 2e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.6 KFP08821.1 - 1.4e-34 119.7 0.3 3.9e-25 89.0 0.0 3.0 2 1 1 3 3 3 2 Diacylglycerol kinase N-terminus DAGK_cat PF00781.24 KFP08821.1 - 1.5e-27 95.7 0.0 2.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFP08821.1 - 3e-21 75.1 34.6 1.1e-12 47.6 7.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFP08821.1 - 1.4e-13 49.3 0.7 4.3e-06 25.9 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP08821.1 - 2.8e-10 40.5 0.5 8.8e-10 38.9 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP08821.1 - 9.5e-10 37.6 0.1 2.7e-05 23.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP08821.1 - 1.1e-08 34.2 0.3 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP08821.1 - 2.9e-06 27.0 3.2 0.01 15.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP08821.1 - 0.00019 21.7 0.2 0.0019 18.5 0.2 2.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1_2 PF03107.16 KFP08821.1 - 0.24 11.7 20.7 0.31 11.4 4.7 2.6 2 0 0 2 2 2 0 C1 domain FA_hydroxylase PF04116.13 KFP08825.1 - 2.8e-28 98.9 11.8 6.1e-28 97.8 11.8 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Homeodomain PF00046.29 KFP08827.1 - 1.1e-22 79.7 7.8 1.1e-22 79.7 7.8 1.8 2 0 0 2 2 2 1 Homeodomain ANF_receptor PF01094.28 KFP08828.1 - 0.0041 16.3 0.1 0.0041 16.3 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region WAPL PF07814.13 KFP08829.1 - 3.9e-117 391.1 8.1 6.9e-117 390.3 8.1 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 KFP08829.1 - 0.00032 20.0 3.9 0.0073 15.5 0.1 2.6 2 1 0 2 2 2 2 Wap1 domain LIM PF00412.22 KFP08830.1 - 1.2e-37 128.0 31.4 7.9e-14 51.6 4.3 3.2 3 0 0 3 3 3 3 LIM domain DUF4749 PF15936.5 KFP08830.1 - 3.7e-10 40.8 0.3 3.7e-10 40.8 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFP08830.1 - 2.3e-08 34.3 0.3 4.3e-08 33.4 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP08830.1 - 3.3e-05 23.6 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP08830.1 - 0.00095 19.5 0.1 0.002 18.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 KFP08831.1 - 7.2e-38 130.3 0.0 9.9e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP08831.1 - 1.2e-37 129.7 0.0 2.1e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP08831.1 - 6.2e-16 57.6 0.7 1.2e-15 56.6 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFP08831.1 - 4.7e-13 50.0 12.1 4.7e-13 50.0 12.1 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP08831.1 - 2.3e-05 23.4 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP08831.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFP08831.1 - 0.08 11.9 0.1 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Comm PF15957.5 KFP08831.1 - 0.15 12.4 0.7 2 8.8 0.1 2.6 3 0 0 3 3 3 0 Commissureless APH PF01636.23 KFP08831.1 - 0.23 11.4 0.0 0.53 10.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family C1q PF00386.21 KFP08832.1 - 4.6e-16 59.2 0.1 8.4e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 C1q domain EMI PF07546.13 KFP08832.1 - 6.2e-14 52.5 4.7 1.5e-13 51.3 4.7 1.7 1 0 0 1 1 1 1 EMI domain Synuclein PF01387.17 KFP08833.1 - 1.8e-50 170.6 24.5 1.9e-50 170.5 24.5 1.0 1 0 0 1 1 1 1 Synuclein YtxH PF12732.7 KFP08833.1 - 0.6 10.7 8.8 8.8 6.9 8.8 2.0 1 1 0 1 1 1 0 YtxH-like protein ELFV_dehydrog PF00208.21 KFP08834.1 - 6.2e-55 186.6 0.0 9e-52 176.2 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFP08834.1 - 1.1e-41 141.8 0.0 2.2e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KFP08834.1 - 0.056 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain C2 PF00168.30 KFP08835.1 - 1.5e-28 99.1 0.1 3.4e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 KFP08835.1 - 0.017 14.9 0.8 0.048 13.5 0.5 1.8 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.6 KFP08835.1 - 0.023 14.3 0.2 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 CEP76 C2 domain NT-C2 PF10358.9 KFP08835.1 - 0.069 12.9 0.2 0.4 10.4 0.0 2.2 2 1 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins GRIN_C PF15235.6 KFP08836.1 - 1.8e-37 128.5 0.4 4.5e-37 127.2 0.1 1.9 2 0 0 2 2 2 1 G protein-regulated inducer of neurite outgrowth C-terminus Tim17 PF02466.19 KFP08837.1 - 6.4e-20 71.6 2.3 7.1e-20 71.4 2.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family E1_dh PF00676.20 KFP08838.1 - 6.4e-88 294.6 0.1 1.2e-87 293.7 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KFP08838.1 - 3.2e-67 225.6 0.0 5e-67 225.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFP08838.1 - 7.5e-55 184.8 0.0 1.7e-54 183.7 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFP08838.1 - 1e-19 69.8 3.5 1.7e-18 65.9 2.0 2.5 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus GGA_N-GAT PF18308.1 KFP08838.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 GGA N-GAT domain Carn_acyltransf PF00755.20 KFP08839.1 - 6.5e-194 645.9 0.0 7.3e-194 645.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase 7tm_1 PF00001.21 KFP08840.1 - 1.8e-24 86.5 10.5 6.9e-23 81.3 10.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP08840.1 - 2.1e-05 24.3 8.4 3.7e-05 23.5 8.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP08840.1 - 3.6 6.9 9.4 2.6 7.4 6.6 2.2 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Cadherin PF00028.17 KFP08841.1 - 2.4e-73 242.6 5.4 1.3e-16 60.8 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Fn3_assoc PF13287.6 KFP08841.1 - 0.059 13.5 1.3 2.7 8.2 0.1 3.4 3 0 0 3 3 3 0 Fn3 associated Cadherin_2 PF08266.12 KFP08841.1 - 0.11 12.3 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 Cadherin-like Big_9 PF17963.1 KFP08841.1 - 0.18 12.6 17.3 1.1 10.1 1.0 5.0 6 0 0 6 6 6 0 Bacterial Ig domain Bax1-I PF01027.20 KFP08842.1 - 9.1e-40 136.7 15.5 1.3e-39 136.1 15.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ABC2_membrane_5 PF13346.6 KFP08842.1 - 8.1 5.9 8.1 19 4.8 0.1 2.5 1 1 0 2 2 2 0 ABC-2 family transporter protein DEAD PF00270.29 KFP08843.1 - 1.1e-53 181.6 0.0 1.9e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFP08843.1 - 0.017 15.1 2.1 0.022 14.8 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3698 PF12479.8 KFP08843.1 - 0.14 12.7 0.8 0.56 10.8 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Ig_3 PF13927.6 KFP08844.1 - 0.019 15.6 0.0 0.019 15.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP08844.1 - 0.028 14.6 0.0 0.028 14.6 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin V-set domain V-set PF07686.17 KFP08845.1 - 2.6e-07 30.8 0.1 2.6e-07 30.8 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP08845.1 - 4.5e-05 23.4 0.0 4.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP08845.1 - 7.4e-05 23.3 0.0 8.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP08845.1 - 0.00013 22.0 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP08845.1 - 0.004 17.5 0.0 0.004 17.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFP08845.1 - 0.0058 16.2 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFP08845.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFP08845.1 - 0.058 12.1 0.0 0.062 12.1 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 KFP08845.1 - 0.07 13.2 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain HLH PF00010.26 KFP08846.1 - 6.1e-19 67.7 0.2 6.1e-19 67.7 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP08846.1 - 0.035 14.0 0.1 0.24 11.3 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain Nicastrin PF05450.15 KFP08847.1 - 1e-71 241.1 0.2 1.5e-71 240.6 0.2 1.2 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 KFP08847.1 - 1.4e-62 210.7 0.0 2.5e-62 209.8 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 KFP08847.1 - 2.5e-09 37.1 0.0 3.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 S_100 PF01023.19 KFP08848.1 - 4.1e-18 64.8 0.2 7.8e-18 63.9 0.0 1.5 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP08848.1 - 3.8e-08 32.3 1.4 1.1e-06 27.7 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP08848.1 - 1.7e-06 28.4 0.1 2.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP08848.1 - 2.3e-05 23.7 1.5 0.00011 21.5 0.4 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP08848.1 - 5.1e-05 22.9 0.7 0.013 15.4 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP08848.1 - 0.00084 19.1 1.2 0.0032 17.3 1.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_11 PF08976.11 KFP08848.1 - 0.011 16.6 0.0 0.013 16.3 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 KFP08848.1 - 0.098 12.6 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand LMBR1 PF04791.16 KFP08849.1 - 2.1e-80 271.1 21.8 1.6e-46 159.3 12.6 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein SH PF01445.17 KFP08849.1 - 0.03 14.3 0.1 0.26 11.3 0.1 2.6 2 0 0 2 2 2 0 Viral small hydrophobic protein Tubulin_C PF03953.17 KFP08850.1 - 4.6e-47 159.3 0.0 8.1e-47 158.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFP08850.1 - 1.4e-42 146.1 0.0 1.9e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFP08850.1 - 0.00093 18.9 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain I-set PF07679.16 KFP08855.1 - 6.2e-40 135.2 1.5 5.3e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP08855.1 - 9.9e-40 135.0 3.1 5.5e-17 62.2 0.1 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP08855.1 - 9.9e-30 102.7 1.5 5.2e-13 49.1 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP08855.1 - 9.3e-26 89.8 0.8 4.1e-11 42.9 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP08855.1 - 2.5e-17 63.0 1.1 2.6e-05 24.3 0.0 5.1 3 2 2 5 5 5 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP08855.1 - 1.3e-10 41.5 0.1 0.032 14.6 0.0 3.6 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP08855.1 - 4.2e-08 33.1 0.5 0.0072 16.4 0.1 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP08855.1 - 4.6e-07 30.0 1.6 0.11 12.8 0.0 4.0 3 2 1 4 4 4 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP08855.1 - 3.7e-06 26.9 1.0 0.1 12.6 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP08855.1 - 7.1e-06 25.5 0.0 0.068 12.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFP08855.1 - 0.00017 21.6 0.7 0.29 11.1 0.2 3.2 2 1 1 3 3 3 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFP08855.1 - 0.0016 18.1 3.6 4.3 7.2 0.2 4.0 3 1 0 3 3 3 2 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFP08855.1 - 0.0018 18.3 0.9 1 9.4 0.1 4.0 3 2 0 3 3 3 1 C17orf99 Ig domain C2-set PF05790.15 KFP08855.1 - 0.059 13.6 0.1 19 5.5 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Neuromodulin PF06614.11 KFP08856.1 - 1.1e-69 234.1 68.1 1.1e-69 234.1 68.1 1.8 2 0 0 2 2 2 1 Neuromodulin Neuromodulin_N PF10580.9 KFP08856.1 - 5.6e-15 54.8 5.6 5.6e-15 54.8 5.6 2.4 2 0 0 2 2 2 1 Gap junction protein N-terminal region IQ PF00612.27 KFP08856.1 - 1.6e-06 27.4 0.4 2.6e-06 26.7 0.4 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Apo-VLDL-II PF05418.11 KFP08859.1 - 1.1e-43 147.7 0.3 1.3e-43 147.4 0.3 1.1 1 0 0 1 1 1 1 Apovitellenin I (Apo-VLDL-II) Claudin_2 PF13903.6 KFP08860.1 - 8e-19 68.1 1.4 1.3e-18 67.5 1.4 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP08860.1 - 2.3e-09 37.4 4.8 1.2e-06 28.5 4.8 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 KFP08860.1 - 0.0021 17.7 6.9 0.0067 16.1 7.0 1.9 1 1 0 1 1 1 1 SUR7/PalI family TMEM190 PF15431.6 KFP08860.1 - 0.064 13.4 0.2 0.064 13.4 0.2 1.8 2 0 0 2 2 2 0 Transmembrane protein 190 Phospholip_A2_1 PF00068.19 KFP08861.1 - 2.4e-33 114.9 15.2 3e-33 114.6 15.2 1.1 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFP08861.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Parvovirus coat protein VP1 V-set PF07686.17 KFP08862.1 - 8.9e-17 61.2 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP08862.1 - 1.9e-09 38.0 0.0 3.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP08862.1 - 1.8e-08 34.4 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP08862.1 - 3.4e-08 33.7 0.0 9.9e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP08862.1 - 3.5e-08 33.4 0.0 7.4e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set_CD47 PF08204.11 KFP08862.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain DUF3872 PF12988.7 KFP08862.1 - 0.047 13.5 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) C1-set PF07654.15 KFP08862.1 - 0.081 13.3 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 KFP08862.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 Receptor_2B4 PF11465.8 KFP08862.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 VASt PF16016.5 KFP08863.1 - 8.9e-37 126.9 2.6 1.6e-36 126.0 2.6 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFP08863.1 - 4.7e-27 94.1 0.2 1.1e-26 92.9 0.2 1.7 1 0 0 1 1 1 1 GRAM domain TarH PF02203.15 KFP08863.1 - 0.007 16.3 0.8 0.017 15.1 0.8 1.6 1 0 0 1 1 1 1 Tar ligand binding domain homologue DUF3377 PF11857.8 KFP08863.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DHHC PF01529.20 KFP08864.1 - 3.6e-31 108.1 8.2 3.6e-31 108.1 8.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase TGT PF01702.18 KFP08866.1 - 4.9e-78 262.7 0.0 5.4e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase 7tm_1 PF00001.21 KFP08867.1 - 3.3e-78 262.7 11.4 4.4e-78 262.2 11.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08867.1 - 1.4e-10 41.0 16.3 9.2e-08 31.8 15.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP08867.1 - 2.2e-05 24.2 15.5 2.2e-05 24.2 15.5 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx BTB PF00651.31 KFP08868.1 - 6.4e-24 84.3 0.1 1.9e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP08868.1 - 3.1e-22 77.7 42.1 1e-06 28.8 1.9 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP08868.1 - 3.5e-20 71.5 42.7 1.9e-06 28.0 2.7 7.2 7 1 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP08868.1 - 1e-15 57.0 35.3 0.00021 21.8 1.5 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP08868.1 - 1.3e-06 28.6 34.2 0.0035 17.7 1.1 6.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KFP08868.1 - 1.1e-05 25.2 6.4 0.43 10.5 0.0 4.4 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFP08868.1 - 4.5e-05 23.3 29.2 0.0024 17.8 0.6 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger BolA PF01722.18 KFP08868.1 - 0.0012 19.0 1.3 0.66 10.3 0.2 3.8 2 1 1 3 3 3 1 BolA-like protein zf-C2H2_2 PF12756.7 KFP08868.1 - 0.0021 18.4 23.8 0.022 15.1 9.3 4.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFP08868.1 - 0.0046 16.7 18.3 0.79 9.5 2.0 4.9 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP08868.1 - 0.0072 16.6 21.4 0.1 12.9 0.7 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP08868.1 - 0.016 15.5 22.2 1.4 9.3 3.4 4.2 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 KFP08868.1 - 0.23 11.3 8.5 18 5.2 0.0 4.8 5 0 0 5 5 5 0 RING-like zinc finger DUF2225 PF09986.9 KFP08868.1 - 2.3 7.9 13.0 1.4 8.6 0.2 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Endonuclease_7 PF02945.15 KFP08868.1 - 4.3 7.3 13.0 1.6 8.7 4.4 3.7 1 1 1 2 2 2 0 Recombination endonuclease VII HNH_5 PF14279.6 KFP08868.1 - 7.4 6.5 13.5 2.3 8.1 0.2 4.0 4 1 0 4 4 4 0 HNH endonuclease Sprouty PF05210.13 KFP08869.1 - 3e-29 101.4 25.8 3e-29 101.4 25.8 1.8 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.23 KFP08869.1 - 2.5e-10 40.3 0.0 4.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Actin PF00022.19 KFP08870.1 - 1.5e-112 376.2 0.0 1.2e-111 373.2 0.0 1.9 1 1 0 1 1 1 1 Actin Ras PF00071.22 KFP08871.1 - 1.8e-67 226.0 1.1 2.2e-67 225.7 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08871.1 - 8.6e-38 129.2 0.1 1.6e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08871.1 - 2e-17 63.2 0.2 2.4e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP08871.1 - 6.6e-07 29.4 0.5 0.011 15.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP08871.1 - 6.5e-06 25.8 0.3 1.8e-05 24.3 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP08871.1 - 7.1e-06 25.5 0.1 9.6e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP08871.1 - 8.1e-06 25.9 0.1 2.7e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP08871.1 - 1.4e-05 24.6 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFP08871.1 - 0.00084 19.8 0.0 0.12 12.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFP08871.1 - 0.0034 16.9 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFP08871.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFP08871.1 - 0.019 14.7 0.1 0.95 9.2 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP08871.1 - 0.044 13.3 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFP08871.1 - 0.044 14.0 0.0 0.084 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP08871.1 - 0.055 14.0 0.0 0.079 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 KFP08871.1 - 0.061 12.6 0.1 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 KFP08871.1 - 0.065 13.2 0.0 0.087 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 KFP08871.1 - 0.074 11.6 0.1 0.16 10.5 0.0 1.5 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein AAA_29 PF13555.6 KFP08871.1 - 0.074 12.8 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KFP08871.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Dioxygenase_N PF04444.14 KFP08871.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus SDF PF00375.18 KFP08873.1 - 1.5e-91 307.4 14.6 1.7e-91 307.2 14.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family VMA21 PF09446.10 KFP08873.1 - 0.1 12.7 2.2 0.42 10.7 1.9 2.3 1 1 0 1 1 1 0 VMA21-like domain SERTA PF06031.13 KFP08874.1 - 3.3e-17 61.8 0.8 5.4e-17 61.2 0.8 1.4 1 0 0 1 1 1 1 SERTA motif Clathrin_bdg PF15045.6 KFP08875.1 - 1.2e-20 73.3 0.0 5.3e-20 71.2 0.0 2.2 2 0 0 2 2 2 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Gal-bind_lectin PF00337.22 KFP08876.1 - 7.7e-26 90.2 0.0 8.3e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin DUF2189 PF09955.9 KFP08877.1 - 0.011 15.9 3.0 0.014 15.6 3.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Hexapep PF00132.24 KFP08878.1 - 0.21 11.4 7.2 34 4.4 0.1 4.1 4 2 0 4 4 4 0 Bacterial transferase hexapeptide (six repeats) Pellino PF04710.14 KFP08879.1 - 4.5e-228 756.8 0.0 5.3e-228 756.6 0.0 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFP08879.1 - 0.017 15.0 7.3 1.4 8.9 3.5 3.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP08879.1 - 0.091 12.6 10.2 1.5 8.8 0.6 3.5 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP08879.1 - 0.43 10.6 0.1 0.43 10.6 0.1 3.4 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFP08879.1 - 0.69 10.3 10.8 0.67 10.3 0.2 3.1 3 0 0 3 3 3 0 Ring finger domain Vps54 PF07928.12 KFP08880.1 - 6.1e-50 169.1 1.4 3.6e-49 166.6 1.0 2.6 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KFP08880.1 - 9.5e-08 31.7 7.6 9.5e-08 31.7 7.6 2.5 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex SBP_bac_6 PF13343.6 KFP08880.1 - 0.14 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein COG2 PF06148.11 KFP08880.1 - 0.15 12.2 4.2 14 5.8 0.0 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UDPGP PF01704.18 KFP08881.1 - 1.7e-198 659.3 0.2 2.1e-198 659.1 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ldh_1_C PF02866.18 KFP08882.1 - 1.8e-44 151.6 0.1 3.9e-44 150.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFP08882.1 - 4.4e-40 137.0 0.1 8.4e-40 136.1 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KFP08882.1 - 0.031 14.2 0.2 0.09 12.7 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Frtz PF11768.8 KFP08883.1 - 2.2e-257 854.7 0.1 2.5e-257 854.5 0.1 1.0 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz NT-C2 PF10358.9 KFP08884.1 - 4.2e-26 91.4 0.3 8.9e-26 90.4 0.3 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CH PF00307.31 KFP08884.1 - 1e-21 77.2 0.0 2.7e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF3585 PF12130.8 KFP08884.1 - 7e-20 71.6 8.4 7e-20 71.6 8.4 3.5 4 1 0 4 4 4 1 Bivalent Mical/EHBP Rab binding domain CAMSAP_CH PF11971.8 KFP08884.1 - 0.00043 20.1 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Isochorismatase PF00857.20 KFP08884.1 - 0.14 12.3 1.0 0.34 11.1 0.2 2.0 2 0 0 2 2 2 0 Isochorismatase family DUF4287 PF14117.6 KFP08884.1 - 0.19 11.9 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Transmemb_17 PF09799.9 KFP08885.1 - 2.9e-29 101.8 14.2 4.1e-29 101.3 14.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF3043 PF11241.8 KFP08885.1 - 0.049 13.7 9.9 0.48 10.5 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) EGF_CA PF07645.15 KFP08886.1 - 6.5e-08 32.7 7.1 6.5e-08 32.7 7.1 1.5 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KFP08886.1 - 8.8e-05 22.6 4.0 0.00016 21.8 4.0 1.4 1 0 0 1 1 1 1 EGF domain Plasmod_Pvs28 PF06247.11 KFP08886.1 - 0.0048 17.2 4.3 0.0075 16.6 4.3 1.3 1 0 0 1 1 1 1 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 KFP08886.1 - 0.0072 16.4 3.1 0.012 15.7 3.1 1.4 1 0 0 1 1 1 1 MSP1 EGF domain 1 hEGF PF12661.7 KFP08886.1 - 0.01 16.5 2.9 0.027 15.1 2.9 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF DUF3844 PF12955.7 KFP08886.1 - 0.03 14.5 0.4 0.047 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) EGF PF00008.27 KFP08886.1 - 0.15 12.4 6.2 0.16 12.3 4.7 1.9 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.6 KFP08886.1 - 0.22 11.8 3.8 0.64 10.4 4.0 1.8 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site Galactosyl_T PF01762.21 KFP08887.1 - 2.7e-42 144.8 0.0 4.2e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFP08887.1 - 0.0029 17.1 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KFP08887.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 COMMD1_N PF17221.3 KFP08888.1 - 8.4e-21 74.2 0.5 8.4e-21 74.2 0.5 1.6 2 0 0 2 2 2 1 COMMD1 N-terminal domain COMM_domain PF07258.14 KFP08888.1 - 3.7e-17 62.2 1.7 3.7e-17 62.2 1.7 1.5 2 0 0 2 2 2 1 COMM domain PRP38 PF03371.15 KFP08888.1 - 0.068 13.0 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 PRP38 family MCM PF00493.23 KFP08889.1 - 1.6e-87 292.3 0.0 2.3e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KFP08889.1 - 4.9e-27 94.2 0.5 9.3e-27 93.3 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KFP08889.1 - 1.8e-24 86.0 1.5 3.4e-24 85.1 1.5 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KFP08889.1 - 3.3e-08 33.2 0.0 6.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFP08889.1 - 9.8e-08 32.1 0.0 3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFP08889.1 - 0.0002 21.2 0.0 0.00054 19.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP08889.1 - 0.0043 17.4 0.2 0.046 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFP08889.1 - 0.011 16.2 0.0 0.036 14.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KFP08889.1 - 0.029 14.3 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 KFP08889.1 - 0.032 13.6 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KFP08889.1 - 0.092 12.2 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Granin PF01271.17 KFP08890.1 - 5.7e-46 157.6 135.7 1.1e-45 156.7 135.7 1.5 1 1 0 1 1 1 1 Granin (chromogranin or secretogranin) DUF4521 PF15021.6 KFP08891.1 - 2e-82 276.1 0.0 2.5e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) GDPD PF03009.17 KFP08892.1 - 3e-61 207.4 0.0 5.6e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 KFP08892.1 - 6.3e-10 38.8 0.0 2.1e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Starch binding domain PI-PLC-X PF00388.19 KFP08892.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain UPF0020 PF01170.18 KFP08893.1 - 2.1e-27 96.1 0.0 2.2e-26 92.8 0.0 2.5 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KFP08893.1 - 1.7e-13 51.0 0.0 3.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP08893.1 - 5.3e-13 49.0 0.0 9.3e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP08893.1 - 4.4e-11 43.3 0.0 1.2e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain THUMP PF02926.17 KFP08893.1 - 5e-07 29.9 0.0 9.7e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 THUMP domain MTS PF05175.14 KFP08893.1 - 5e-07 29.4 0.0 8.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KFP08893.1 - 7.1e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 KFP08893.1 - 0.011 15.2 0.0 0.039 13.4 0.0 1.7 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 KFP08893.1 - 0.017 15.9 0.0 0.043 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 KFP08893.1 - 0.037 13.3 0.1 0.17 11.1 0.0 2.0 2 1 0 2 2 2 0 N-6 DNA Methylase Ribosomal_S5_C PF03719.15 KFP08894.1 - 4.1e-23 80.6 0.2 7e-23 79.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFP08894.1 - 3.5e-16 58.9 2.9 3.5e-16 58.9 2.9 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain YbfN PF13982.6 KFP08894.1 - 0.084 13.2 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 YbfN-like lipoprotein Calx-beta PF03160.14 KFP08895.1 - 2.9e-62 207.1 6.2 1.4e-35 121.5 0.9 2.6 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 KFP08895.1 - 1.6e-60 203.5 31.4 1e-33 116.4 11.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KFP08895.1 - 3.2e-51 173.1 5.8 5.1e-51 172.4 5.8 1.3 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain DnaG_DnaB_bind PF08278.11 KFP08895.1 - 0.077 13.6 2.0 0.16 12.6 2.0 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding BSD PF03909.17 KFP08897.1 - 0.065 13.3 0.6 11 6.1 0.2 2.8 2 0 0 2 2 2 0 BSD domain CarD_CdnL_TRCF PF02559.16 KFP08897.1 - 0.15 12.8 0.3 0.28 11.9 0.3 1.7 1 1 0 1 1 1 0 CarD-like/TRCF domain DUF5320 PF17253.2 KFP08897.1 - 0.18 12.9 0.6 0.18 12.9 0.6 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF4407 PF14362.6 KFP08897.1 - 3.9 6.7 21.7 4.8 6.4 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 KFP08897.1 - 4 7.4 6.4 0.67 9.9 0.4 2.4 1 1 0 2 2 2 0 Sec20 DUF2730 PF10805.8 KFP08897.1 - 6.5 6.9 9.4 0.55 10.4 1.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) DEAD PF00270.29 KFP08898.1 - 1.2e-42 145.7 0.2 1.8e-42 145.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP08898.1 - 3.1e-32 111.2 0.0 1.7e-31 108.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP08898.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFP08898.1 - 0.0002 21.8 0.0 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP08898.1 - 0.00022 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 KFP08898.1 - 0.0047 15.8 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KFP08898.1 - 0.049 13.9 0.0 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 KFP08898.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KFP08898.1 - 0.12 12.4 0.2 0.41 10.6 0.1 2.1 1 1 1 2 2 2 0 Flavivirus DEAD domain Fanconi_A PF03511.14 KFP08898.1 - 0.19 11.7 0.3 1.5 8.8 0.0 2.3 3 0 0 3 3 3 0 Fanconi anaemia group A protein GBP PF02263.19 KFP08899.1 - 1e-102 342.9 0.1 1.4e-102 342.5 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFP08899.1 - 7.3e-06 25.6 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFP08899.1 - 0.0057 17.0 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain ATP-synt_A PF00119.20 KFP08899.1 - 0.017 15.1 0.2 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 ATP synthase A chain RRM_5 PF13893.6 KFP08900.1 - 1.8e-58 195.6 3.5 4.1e-55 184.7 0.1 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFP08900.1 - 1.3e-17 63.4 1.1 7.2e-07 28.9 0.1 4.5 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFP08900.1 - 2.2e-09 37.4 0.1 9.4e-09 35.4 0.0 2.1 3 0 0 3 3 3 1 RRM-like domain RRM_occluded PF16842.5 KFP08900.1 - 0.00017 21.4 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP08900.1 - 0.0019 18.2 0.0 0.007 16.4 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 KFP08900.1 - 0.0082 16.2 0.1 1.2 9.2 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 RL PF17797.1 KFP08900.1 - 0.1 12.6 0.0 28 4.7 0.0 3.2 3 0 0 3 3 3 0 RL domain Aldose_epim PF01263.20 KFP08901.1 - 1.2e-80 271.1 0.0 1.4e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.22 KFP08902.1 - 8.4e-17 60.8 0.0 1.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP08902.1 - 0.00058 19.5 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFP08902.1 - 0.0006 19.8 7.7 0.0012 18.8 7.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFP08902.1 - 0.00082 19.3 2.2 0.0019 18.1 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Gemin6 PF06372.12 KFP08903.1 - 5.9e-66 221.1 0.3 6.4e-66 221.0 0.3 1.0 1 0 0 1 1 1 1 Gemin6 protein Ish1 PF10281.9 KFP08903.1 - 0.025 14.9 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF3108 PF11306.8 KFP08903.1 - 0.066 13.2 0.0 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) AD PF09793.9 KFP08903.1 - 0.09 12.9 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 Anticodon-binding domain 53-BP1_Tudor PF09038.10 KFP08903.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor RRM_1 PF00076.22 KFP08904.1 - 5e-16 58.3 0.0 7e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFP08904.1 - 0.00057 19.8 7.7 0.0011 18.9 7.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFP08904.1 - 0.0008 19.3 2.3 0.0018 18.2 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KFP08904.1 - 0.0021 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP08904.1 - 0.058 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif OB_NTP_bind PF07717.16 KFP08905.1 - 4e-21 75.2 0.6 2e-20 72.9 0.0 2.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFP08905.1 - 7.3e-18 64.8 0.4 5e-17 62.1 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) RWD PF05773.22 KFP08905.1 - 4.9e-16 59.1 1.1 1.1e-15 57.9 0.0 2.3 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.31 KFP08905.1 - 7.8e-14 52.0 0.0 3.1e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP08905.1 - 1e-10 41.7 0.4 2.4e-10 40.5 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCCH_4 PF18044.1 KFP08905.1 - 3.4e-08 33.1 3.8 9.3e-08 31.7 3.8 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KFP08905.1 - 4.6e-06 27.3 0.5 1.3e-05 25.8 0.5 1.8 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KFP08905.1 - 4.9e-05 23.2 9.1 0.00016 21.6 9.1 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFP08905.1 - 0.00024 20.9 5.5 0.00024 20.9 5.5 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UBA PF00627.31 KFP08905.1 - 0.00035 20.4 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain AAA_22 PF13401.6 KFP08905.1 - 0.0021 18.3 0.2 0.0098 16.2 0.2 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP08905.1 - 0.0041 17.5 0.1 0.014 15.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain zf-CCCH_2 PF14608.6 KFP08905.1 - 0.014 15.9 3.1 0.031 14.8 3.1 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger T2SSE PF00437.20 KFP08905.1 - 0.014 14.4 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KFP08905.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KFP08905.1 - 0.027 14.5 1.9 0.42 10.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFP08905.1 - 0.033 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RhoGEF PF00621.20 KFP08906.1 - 1.7e-16 61.0 5.3 2.1e-16 60.7 5.3 1.1 1 0 0 1 1 1 1 RhoGEF domain RasGEF PF00617.19 KFP08908.1 - 2.5e-49 167.9 0.4 5.3e-49 166.8 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFP08908.1 - 9.6e-32 109.4 0.0 3.4e-31 107.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFP08908.1 - 2.4e-16 60.5 1.7 5.8e-16 59.3 0.1 2.4 2 0 0 2 2 2 1 RhoGEF domain Histone PF00125.24 KFP08908.1 - 3.7e-12 46.8 1.6 4.5e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PH PF00169.29 KFP08908.1 - 5.1e-11 43.0 2.4 5.7e-11 42.9 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_10 PF15411.6 KFP08908.1 - 0.0013 19.0 0.1 0.0048 17.1 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFP08908.1 - 0.0017 18.3 0.0 0.007 16.3 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFP08908.1 - 0.0023 17.8 0.1 0.0089 15.8 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DUF445 PF04286.12 KFP08908.1 - 0.18 11.6 3.9 10 5.8 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF445) CNH PF00780.22 KFP08909.1 - 2.6e-70 237.2 0.5 3.3e-70 236.8 0.5 1.1 1 0 0 1 1 1 1 CNH domain QVR PF17064.5 KFP08909.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.0 2 0 0 2 2 2 0 Sleepless protein Ldl_recept_b PF00058.17 KFP08910.1 - 8.5e-154 499.8 45.3 1.2e-13 51.3 0.0 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP08910.1 - 2.1e-40 136.7 62.8 1.1e-12 48.0 8.1 5.5 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFP08910.1 - 1.5e-31 108.3 50.1 4.5e-11 42.8 10.3 4.4 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 KFP08910.1 - 1.5e-22 80.2 0.0 4.4e-05 22.9 0.0 5.7 4 2 1 5 5 5 5 Domain of unknown function (DUF5050) SGL PF08450.12 KFP08910.1 - 1.3e-19 70.8 22.5 0.013 15.1 0.6 11.6 7 5 3 11 11 11 6 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KFP08910.1 - 1.5e-08 34.7 0.0 11 6.3 0.0 8.2 8 1 1 9 9 8 1 Arylesterase EGF PF00008.27 KFP08910.1 - 4.9e-05 23.5 64.2 0.0078 16.5 3.8 6.1 6 0 0 6 6 4 4 EGF-like domain NHL PF01436.21 KFP08910.1 - 0.021 14.9 0.0 15 5.8 0.0 5.1 5 0 0 5 5 5 0 NHL repeat Methyltransf_12 PF08242.12 KFP08910.1 - 0.043 14.5 0.3 2e+02 2.8 0.0 5.7 5 2 1 6 6 6 0 Methyltransferase domain cEGF PF12662.7 KFP08910.1 - 0.061 13.3 22.3 0.036 14.0 1.5 4.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like Insulin_TMD PF17870.1 KFP08910.1 - 0.098 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SAPS PF04499.15 KFP08911.1 - 9.3e-106 354.5 12.6 9e-67 225.9 7.8 3.9 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein FliC PF12445.8 KFP08911.1 - 0.018 15.4 2.4 0.061 13.7 2.4 1.8 1 0 0 1 1 1 0 Flagellin protein Atx10homo_assoc PF09759.9 KFP08911.1 - 0.059 13.4 2.0 0.62 10.1 0.1 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain GMAP PF06540.11 KFP08912.1 - 8.5e-27 93.0 0.1 1.1e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Galanin message associated peptide (GMAP) Galanin PF01296.18 KFP08912.1 - 2.5e-20 72.1 1.4 2.5e-20 72.1 1.4 1.6 2 0 0 2 2 2 1 Galanin Carn_acyltransf PF00755.20 KFP08913.1 - 1.2e-199 664.8 0.0 1.4e-199 664.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 KFP08913.1 - 5.6e-28 96.7 0.2 1.2e-27 95.6 0.2 1.6 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus MACPF PF01823.19 KFP08914.1 - 1.6e-23 84.0 0.0 2.6e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DTC PF18102.1 KFP08915.1 - 2.6e-58 195.9 0.0 4.6e-58 195.1 0.0 1.4 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_UBOX PF13445.6 KFP08915.1 - 1.9e-08 34.2 1.2 5.3e-08 32.7 1.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP08915.1 - 7.2e-08 32.2 1.6 1.6e-07 31.1 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP08915.1 - 9.9e-08 32.2 2.1 4.1e-07 30.2 2.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP08915.1 - 2.9e-06 27.5 1.0 2.9e-06 27.5 1.0 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP08915.1 - 2.1e-05 24.4 1.5 5e-05 23.2 1.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFP08915.1 - 9.4e-05 22.1 4.2 0.0084 15.8 0.6 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFP08915.1 - 0.00017 21.6 1.6 0.00035 20.6 1.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFP08915.1 - 0.00017 21.3 5.9 0.065 13.1 3.1 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP08915.1 - 0.0023 18.0 3.0 0.01 16.0 0.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFP08915.1 - 0.011 15.8 1.3 0.016 15.3 0.2 1.8 2 0 0 2 2 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 KFP08915.1 - 0.012 15.2 0.3 0.012 15.2 0.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFP08915.1 - 0.064 13.1 2.6 0.29 11.0 2.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KFP08915.1 - 0.068 13.1 0.8 0.068 13.1 0.8 2.2 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KFP08915.1 - 0.075 12.8 1.5 0.13 12.1 0.2 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFP08915.1 - 0.079 13.1 1.9 0.29 11.4 1.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Trm112p PF03966.16 KFP08915.1 - 0.084 13.5 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 Trm112p-like protein zinc_ribbon_4 PF13717.6 KFP08915.1 - 0.19 11.7 1.2 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KFP08915.1 - 0.22 11.4 3.4 3 7.8 0.4 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 KFP08915.1 - 1.2 9.2 5.6 5.9 7.0 1.3 3.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-RING-like PF08746.11 KFP08915.1 - 3 8.2 5.5 0.63 10.4 1.3 2.1 2 0 0 2 2 1 0 RING-like domain Ig_3 PF13927.6 KFP08916.1 - 8.5e-32 109.6 0.5 3.5e-14 53.2 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP08916.1 - 9.2e-25 86.8 0.3 3.3e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP08916.1 - 1e-24 86.4 0.1 8.7e-11 41.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP08916.1 - 4.3e-24 84.5 0.2 8.5e-10 38.7 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP08916.1 - 1.2e-17 64.1 1.7 4.3e-07 30.1 0.1 4.4 3 1 1 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP08916.1 - 6.5e-12 45.4 0.0 6e-10 39.1 0.0 3.2 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP08916.1 - 2e-05 24.6 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFP08916.1 - 0.00094 18.9 0.5 0.19 11.5 0.0 2.9 3 0 0 3 3 2 1 Adenovirus E3 region protein CR1 C2-set PF05790.15 KFP08916.1 - 0.0052 16.9 0.0 33 4.7 0.0 4.2 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Syndecan PF01034.20 KFP08916.1 - 0.014 15.3 0.0 0.58 10.1 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain C1-set PF07654.15 KFP08916.1 - 0.034 14.5 0.1 0.67 10.4 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFP08916.1 - 0.088 12.9 0.0 0.65 10.1 0.0 2.5 3 1 0 3 3 3 0 C17orf99 Ig domain DUF3439 PF11921.8 KFP08916.1 - 0.16 12.0 7.8 0.33 10.9 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) V-set_2 PF15910.5 KFP08916.1 - 0.2 11.8 1.3 3.7 7.7 0.1 2.9 2 1 1 3 3 3 0 ICOS V-set domain RNase_T PF00929.24 KFP08917.1 - 1.2e-20 74.7 0.0 1.6e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KFP08917.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like DUF4462 PF14692.6 KFP08918.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ig_2 PF13895.6 KFP08919.1 - 0.00022 21.5 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP08919.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP08919.1 - 0.0038 16.8 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP08919.1 - 0.0039 17.2 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFP08919.1 - 0.0059 17.2 0.0 0.018 15.6 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP08919.1 - 0.036 14.2 0.0 0.18 12.0 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin domain TSP_1 PF00090.19 KFP08919.1 - 0.13 12.5 5.6 0.24 11.7 5.6 1.4 1 0 0 1 1 1 0 Thrombospondin type 1 domain WD40 PF00400.32 KFP08920.1 - 9.6e-11 42.1 17.2 0.00036 21.3 2.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP08920.1 - 2.8e-09 37.1 0.7 0.026 14.8 0.0 4.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFP08920.1 - 0.12 10.6 0.1 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 KFP08921.1 - 5.5e-37 127.6 0.0 1.6e-36 126.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08921.1 - 1.1e-35 123.2 0.0 1.9e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP08921.1 - 3.6e-05 22.7 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP08921.1 - 0.0001 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP08921.1 - 0.00038 19.5 0.0 0.00096 18.2 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP08921.1 - 0.002 17.5 0.7 0.0042 16.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP08921.1 - 0.11 12.4 2.5 0.3 11.0 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Tmemb_cc2 PF10267.9 KFP08922.1 - 2.2e-159 530.9 29.9 1.4e-89 301.1 17.0 2.1 1 1 1 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein 7TMR-HDED PF07697.11 KFP08922.1 - 0.0017 18.5 12.7 0.18 11.9 0.3 2.2 2 0 0 2 2 2 2 7TM-HD extracellular TraG_N PF07916.11 KFP08922.1 - 0.0033 16.3 0.4 0.0033 16.3 0.4 1.6 2 0 0 2 2 2 1 TraG-like protein, N-terminal region LMBR1 PF04791.16 KFP08922.1 - 0.0041 16.1 9.6 0.0083 15.1 4.0 2.0 2 0 0 2 2 2 1 LMBR1-like membrane protein Atg14 PF10186.9 KFP08922.1 - 0.023 13.8 19.5 0.022 13.9 3.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2313 PF10076.9 KFP08922.1 - 0.035 14.0 0.5 0.035 14.0 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) GET2 PF08690.10 KFP08922.1 - 0.046 13.4 0.2 0.046 13.4 0.2 2.4 2 1 0 2 2 2 0 GET complex subunit GET2 AI-2E_transport PF01594.16 KFP08922.1 - 0.047 12.8 7.9 4.4 6.4 0.0 3.0 3 1 0 3 3 3 0 AI-2E family transporter Prominin PF05478.11 KFP08922.1 - 0.077 10.9 21.2 0.15 10.0 11.0 2.6 2 1 1 3 3 3 0 Prominin DUF1479 PF07350.12 KFP08922.1 - 0.08 11.7 5.5 0.1 11.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Lipoprotein_20 PF13942.6 KFP08922.1 - 0.29 11.0 17.0 0.81 9.6 1.5 2.6 2 1 0 2 2 2 0 YfhG lipoprotein Baculo_PEP_C PF04513.12 KFP08922.1 - 0.54 10.3 13.4 0.065 13.3 1.7 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1690 PF07956.11 KFP08922.1 - 0.62 10.5 22.1 2.7 8.4 5.0 2.8 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) CortBP2 PF09727.9 KFP08922.1 - 0.94 9.4 26.6 0.042 13.8 13.0 2.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 OmpH PF03938.14 KFP08922.1 - 3.1 8.1 36.7 0.59 10.5 11.9 3.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF4131 PF13567.6 KFP08922.1 - 5.6 6.6 5.3 12 5.5 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF87 PF01935.17 KFP08922.1 - 7.6 6.5 9.4 15 5.6 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Phage_GPO PF05929.11 KFP08922.1 - 9.6 5.7 23.7 0.43 10.2 4.4 3.3 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Pkinase PF00069.25 KFP08923.1 - 7e-68 228.8 0.1 1.1e-67 228.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08923.1 - 1.8e-38 132.3 0.0 2.7e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08923.1 - 7.2e-07 28.8 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP08923.1 - 8.5e-07 28.2 0.4 1.4e-06 27.6 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP08923.1 - 1.7e-05 24.5 0.9 2.7e-05 23.8 0.9 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP08923.1 - 0.00011 21.6 0.3 0.00019 20.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP08923.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kelch_1 PF01344.25 KFP08924.1 - 4e-49 164.0 3.0 8.3e-11 41.3 0.0 7.1 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.6 KFP08924.1 - 6.6e-38 127.8 1.0 2.6e-08 33.8 0.0 7.1 4 3 3 7 7 7 7 Kelch motif Kelch_2 PF07646.15 KFP08924.1 - 7.2e-23 79.6 0.1 4.5e-06 26.4 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP08924.1 - 1.4e-21 76.2 0.1 6.2e-06 26.1 0.0 6.4 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP08924.1 - 2.8e-19 68.9 0.1 0.00026 21.2 0.0 6.0 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP08924.1 - 7.1e-10 38.7 1.2 0.0056 16.7 0.0 5.3 6 0 0 6 6 6 2 Kelch motif WYL_2 PF10902.8 KFP08924.1 - 0.0064 16.8 1.4 1.1 9.7 0.0 3.2 4 0 0 4 4 4 1 WYL_2, Sm-like SH3 beta-barrel fold Pkinase PF00069.25 KFP08925.1 - 3.6e-69 233.1 0.0 4.4e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08925.1 - 2.5e-33 115.5 0.0 3.6e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP08925.1 - 1.5e-05 24.4 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP08925.1 - 7.5e-05 21.8 0.2 0.00023 20.2 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP08925.1 - 0.0016 17.9 0.2 0.0031 16.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFP08925.1 - 0.067 12.2 0.1 0.12 11.4 0.1 1.3 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFP08925.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KFP08926.1 - 4.5e-10 39.0 39.9 1e-06 28.0 23.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ets PF00178.22 KFP08927.1 - 5e-36 123.0 1.8 7.9e-36 122.4 1.8 1.3 1 0 0 1 1 1 1 Ets-domain MFS_1 PF07690.16 KFP08928.1 - 5.7e-14 51.8 33.4 1.3e-13 50.7 24.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP08928.1 - 4.8e-07 28.7 2.2 4.8e-07 28.7 2.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 KFP08928.1 - 0.0023 17.0 0.9 0.0023 17.0 0.9 2.1 3 0 0 3 3 3 1 PUCC protein DUF553 PF04473.12 KFP08928.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.22 KFP08930.1 - 3.5e-29 101.5 0.0 4e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08930.1 - 5.3e-16 58.9 0.0 8.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08930.1 - 3.4e-09 36.4 0.1 4.6e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 KFP08930.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 KFP08930.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Agenet PF05641.12 KFP08930.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Agenet domain MgtE PF01769.16 KFP08931.1 - 2.9e-55 186.0 24.9 1.2e-30 106.4 3.5 2.8 3 0 0 3 3 3 2 Divalent cation transporter Peptidase_M20 PF01546.28 KFP08932.1 - 3.3e-32 111.9 0.0 5.2e-32 111.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFP08932.1 - 2.4e-16 59.6 0.0 4.8e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Ntox3 PF15536.6 KFP08932.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 3 Sulfate_transp PF00916.20 KFP08933.1 - 1.8e-73 247.5 23.0 7.4e-63 212.6 14.3 2.3 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 KFP08933.1 - 2e-25 88.7 0.0 3.3e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Ras PF00071.22 KFP08934.1 - 1.9e-32 112.1 0.0 2.1e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08934.1 - 1.1e-12 48.2 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08934.1 - 9e-09 35.0 0.0 9.1e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP08934.1 - 0.0037 16.8 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KFP08934.1 - 0.036 14.1 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain 7tm_1 PF00001.21 KFP08935.1 - 1.8e-51 175.0 8.5 2.1e-51 174.8 8.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08935.1 - 1.2e-09 38.0 4.2 1.8e-09 37.4 4.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP08935.1 - 1.3e-05 25.1 2.7 2.1e-05 24.4 2.7 1.3 1 0 0 1 1 1 1 Olfactory receptor Srg PF02118.21 KFP08935.1 - 0.0042 16.8 4.8 0.0042 16.8 4.8 2.2 2 1 1 3 3 3 1 Srg family chemoreceptor Git3 PF11710.8 KFP08935.1 - 0.17 11.6 7.7 0.33 10.7 7.7 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 FAM72 PF14976.6 KFP08936.1 - 3.2e-38 131.1 0.2 3.5e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 FAM72 protein Pkinase PF00069.25 KFP08937.1 - 7.8e-41 140.2 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TBK1_ULD PF18396.1 KFP08937.1 - 1.4e-32 111.5 1.1 2.4e-32 110.7 1.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_Tyr PF07714.17 KFP08937.1 - 6.9e-25 87.8 0.0 9.9e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 KFP08937.1 - 1.7e-11 44.2 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase_fungal PF17667.1 KFP08937.1 - 0.00041 19.2 0.0 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFP08937.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Nore1-SARAH PF16517.5 KFP08938.1 - 1.3e-18 66.6 5.1 1.3e-18 66.6 5.1 2.5 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 KFP08938.1 - 5.2e-17 62.3 0.0 2.5e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pre-PUA PF17832.1 KFP08939.1 - 1.5e-20 73.7 0.2 8.5e-20 71.2 0.1 2.5 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 KFP08939.1 - 1.6e-20 73.4 0.3 3.3e-20 72.4 0.3 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.20 KFP08939.1 - 1e-05 25.4 0.2 7.8e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 PUA domain SWIB PF02201.18 KFP08939.1 - 0.004 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.25 KFP08942.1 - 1.8e-58 198.0 0.1 3.7e-58 197.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08942.1 - 2.7e-21 76.0 0.1 6.4e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP08942.1 - 2e-05 24.7 0.0 0.0029 17.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFP08942.1 - 0.0015 18.2 3.0 0.0031 17.1 0.4 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KFP08942.1 - 0.004 16.8 1.6 0.0073 15.9 1.6 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFP08942.1 - 0.016 14.6 0.2 0.033 13.5 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFP08942.1 - 0.022 14.3 3.8 0.16 11.5 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Staphylcoagulse PF04022.12 KFP08942.1 - 0.066 12.8 0.5 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 Staphylocoagulase repeat Pkinase PF00069.25 KFP08943.1 - 1.2e-63 215.0 0.0 1.5e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08943.1 - 5.4e-27 94.7 0.0 7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP08943.1 - 1.6e-06 27.6 0.1 2.4e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP08943.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP08943.1 - 0.0044 15.9 0.0 0.0062 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFP08943.1 - 0.048 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SARG PF15385.6 KFP08944.1 - 5.9e-107 359.3 43.0 1.4e-51 176.4 6.7 4.0 2 1 2 4 4 4 4 Specifically androgen-regulated gene protein Tenui_PVC2 PF06656.11 KFP08944.1 - 0.05 11.5 0.2 0.07 11.0 0.2 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein OTU PF02338.19 KFP08945.1 - 1.9e-05 25.1 0.0 3.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.7 KFP08945.1 - 0.038 14.3 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP08945.1 - 0.57 10.6 2.4 3.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type 6PF2K PF01591.18 KFP08946.1 - 1.7e-101 338.2 1.3 2.4e-101 337.7 1.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFP08946.1 - 1.2e-41 142.6 0.0 1.5e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFP08946.1 - 7.5e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFP08946.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KFP08946.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain His_Phos_2 PF00328.22 KFP08946.1 - 0.058 12.7 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) APS_kinase PF01583.20 KFP08946.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ASC PF00858.24 KFP08947.1 - 7.9e-20 71.2 0.0 8.8e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel 7tm_2 PF00002.24 KFP08948.1 - 2.6e-75 252.9 21.9 3.2e-75 252.6 21.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP08948.1 - 2.1e-16 59.9 1.2 4.5e-16 58.9 1.2 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF2976 PF11190.8 KFP08948.1 - 0.16 11.8 1.4 16 5.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4574 PF15141.6 KFP08948.1 - 0.19 11.7 0.3 19 5.2 0.1 2.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Ig_3 PF13927.6 KFP08949.1 - 0.0053 17.3 0.0 0.011 16.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP08949.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.7 1 1 1 2 2 2 0 Immunoglobulin domain Sp38 PF07354.12 KFP08949.1 - 0.1 12.0 0.4 0.14 11.6 0.4 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) V-set PF07686.17 KFP08949.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain DUF1072 PF06380.11 KFP08950.1 - 0.04 13.8 6.3 0.43 10.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Tmemb_9 PF05434.11 KFP08950.1 - 0.047 13.6 0.1 0.061 13.2 0.1 1.1 1 0 0 1 1 1 0 TMEM9 Integrin_beta PF00362.18 KFP08951.1 - 1.7e-111 371.8 0.0 2.4e-111 371.3 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFP08951.1 - 2.7e-22 79.1 9.1 2.7e-22 79.1 9.1 4.7 3 1 2 5 5 5 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFP08951.1 - 9.6e-13 48.0 10.8 9.6e-13 48.0 10.8 6.0 7 0 0 7 7 7 4 Integrin beta epidermal growth factor like domain 1 PSI_integrin PF17205.3 KFP08951.1 - 1.1e-11 44.3 4.0 1.1e-11 44.3 4.0 5.3 5 0 0 5 5 5 1 Integrin plexin domain EGF_2 PF07974.13 KFP08951.1 - 3.1e-10 40.2 101.3 0.00013 22.3 16.6 6.5 5 2 2 7 7 7 4 EGF-like domain Integrin_b_cyt PF08725.11 KFP08951.1 - 7.8e-09 35.1 0.9 7.8e-09 35.1 0.9 2.1 3 0 0 3 3 3 1 Integrin beta cytoplasmic domain RNA_pol_A_CTD PF03118.15 KFP08951.1 - 0.061 13.1 0.2 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Pkinase PF00069.25 KFP08952.1 - 9e-63 212.1 0.8 1.5e-62 211.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08952.1 - 4e-36 124.6 0.0 1.5e-35 122.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase GIT_CC PF16559.5 KFP08952.1 - 0.16 11.8 3.7 0.35 10.8 0.7 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Vir_act_alpha_C PF10400.9 KFP08952.1 - 0.51 11.1 13.2 0.19 12.5 0.5 3.4 3 1 0 3 3 3 0 Virulence activator alpha C-term Cytochrom_B561 PF03188.16 KFP08954.1 - 6.4e-37 126.7 5.9 1.4e-36 125.7 5.9 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4401 PF14351.6 KFP08954.1 - 0.0028 17.0 7.6 0.0084 15.5 7.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4401) DUF2516 PF10724.9 KFP08954.1 - 0.034 14.4 0.9 0.034 14.4 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) UPF0016 PF01169.19 KFP08954.1 - 0.065 13.6 0.6 0.065 13.6 0.6 2.9 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF202 PF02656.15 KFP08954.1 - 0.2 12.1 11.4 1.6 9.2 2.7 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF202) DUF4293 PF14126.6 KFP08954.1 - 0.33 11.2 1.9 17 5.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Ni_hydr_CYTB PF01292.20 KFP08954.1 - 0.83 9.2 16.9 0.71 9.5 9.4 3.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4079 PF13301.6 KFP08954.1 - 2.6 8.2 11.5 0.17 12.1 5.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Pkinase PF00069.25 KFP08956.1 - 9.2e-56 189.1 0.0 2.5e-55 187.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP08956.1 - 9e-32 110.4 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFP08956.1 - 2.3e-11 43.4 0.1 5.7e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFP08956.1 - 5.6e-05 22.6 0.0 0.004 16.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFP08956.1 - 0.029 13.4 0.1 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DUF2340 PF10209.9 KFP08956.1 - 0.053 14.0 0.2 0.11 13.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) FTA2 PF13095.6 KFP08956.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFP08956.1 - 0.14 10.9 0.0 0.29 9.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Guanylate_kin PF00625.21 KFP08957.1 - 9.6e-43 146.0 0.9 1.8e-42 145.1 0.9 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFP08957.1 - 8e-25 86.4 4.4 5.5e-13 48.4 0.5 2.7 2 0 0 2 2 2 2 L27 domain PDZ PF00595.24 KFP08957.1 - 2.3e-11 43.9 0.8 4.8e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP08957.1 - 8.8e-09 35.1 0.6 2.3e-08 33.8 0.2 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP08957.1 - 1.8e-05 25.0 0.1 6.8e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 KFP08957.1 - 0.0066 16.1 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP08957.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain NPBW PF15180.6 KFP08957.1 - 0.02 14.8 0.2 9.1 6.2 0.0 3.1 3 0 0 3 3 3 0 Neuropeptides B and W Ras PF00071.22 KFP08958.1 - 2.4e-42 144.3 0.1 9.9e-42 142.3 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFP08958.1 - 3.1e-21 75.8 0.2 6.1e-21 74.9 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08958.1 - 3.2e-12 46.3 0.1 4e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP08958.1 - 0.0016 18.1 0.0 0.0035 16.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP08958.1 - 0.085 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DSPc PF00782.20 KFP08959.1 - 3.8e-34 117.4 0.1 4.6e-34 117.1 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP08959.1 - 4e-05 23.3 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP08959.1 - 0.00036 20.8 0.0 0.00048 20.4 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFP08959.1 - 0.0022 18.1 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate baeRF_family7 PF18849.1 KFP08959.1 - 0.0038 17.4 0.1 0.0053 17.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 7 DUF442 PF04273.13 KFP08959.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative phosphatase (DUF442) baeRF_family6 PF18848.1 KFP08959.1 - 0.042 14.3 0.1 0.06 13.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 Sclerostin PF05463.11 KFP08960.1 - 4e-66 222.5 6.7 4.5e-66 222.4 6.7 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 KFP08960.1 - 3.7e-17 62.4 4.3 6e-17 61.7 4.3 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP08960.1 - 0.00054 20.2 6.9 0.0016 18.7 6.9 1.8 1 1 0 1 1 1 1 Cystine-knot domain Homeodomain PF00046.29 KFP08961.1 - 8.8e-24 83.1 8.0 1.1e-23 82.9 8.0 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP08961.1 - 0.053 13.4 0.7 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain ETS_PEA3_N PF04621.13 KFP08962.1 - 3.8e-85 286.8 27.5 2e-84 284.5 27.5 1.9 1 1 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.22 KFP08962.1 - 7e-39 132.2 0.1 1.2e-38 131.4 0.1 1.4 1 0 0 1 1 1 1 Ets-domain DUF1356 PF07092.12 KFP08963.1 - 3e-101 337.6 6.0 3.5e-101 337.3 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFP08963.1 - 0.0027 17.6 0.5 0.0051 16.7 0.5 1.4 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein N_BRCA1_IG PF16158.5 KFP08964.1 - 3.2e-31 108.1 0.9 9.8e-31 106.5 0.2 2.2 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 KFP08964.1 - 7.9e-12 44.9 0.2 1.6e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 KFP08964.1 - 0.00011 22.0 8.2 0.00029 20.6 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2681 PF10883.8 KFP08964.1 - 1 9.8 5.1 2.6 8.5 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Ribosomal_L27e PF01777.18 KFP08965.1 - 2e-39 133.8 8.8 2.3e-39 133.6 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family RUN PF02759.19 KFP08966.1 - 5.3e-35 120.3 0.0 9.5e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 RUN domain FliD_C PF07195.12 KFP08966.1 - 0.78 9.1 3.0 7.8 5.8 3.0 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PAP2 PF01569.21 KFP08967.1 - 4.5e-18 65.3 6.4 4.5e-18 65.3 6.4 2.0 2 1 0 2 2 2 1 PAP2 superfamily Sulfate_transp PF00916.20 KFP08967.1 - 0.00022 20.1 0.5 0.0003 19.7 0.5 1.2 1 0 0 1 1 1 1 Sulfate permease family PspC PF04024.12 KFP08967.1 - 0.052 13.4 0.1 28 4.6 0.0 3.4 3 1 0 3 3 3 0 PspC domain DUF373 PF04123.13 KFP08967.1 - 5.2 6.4 5.0 2.5 7.4 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Cu_amine_oxid PF01179.20 KFP08968.1 - 1.7e-125 419.1 0.0 2.3e-125 418.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFP08968.1 - 6.2e-18 65.1 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFP08968.1 - 2.1e-13 50.3 0.0 3.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 KFP08968.1 - 0.00067 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) bMG6 PF17962.1 KFP08968.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 PA28_beta PF02252.18 KFP08969.1 - 4.8e-65 217.6 3.4 6.3e-65 217.3 3.4 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KFP08969.1 - 3.3e-24 84.7 0.7 7.5e-24 83.6 0.7 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit TMF_TATA_bd PF12325.8 KFP08969.1 - 0.12 12.6 1.7 0.2 11.9 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cyclin_N PF00134.23 KFP08970.1 - 8.8e-08 31.9 2.4 0.0013 18.5 0.2 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain ESCRT-II PF05871.12 KFP08971.1 - 2.9e-23 82.7 0.2 4.4e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit LisH_TPL PF17814.1 KFP08971.1 - 0.019 14.6 0.2 4.7 7.0 0.3 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain PRC2_HTH_1 PF18118.1 KFP08972.1 - 1e-28 100.1 0.7 1e-28 100.1 0.7 2.1 3 0 0 3 3 3 1 Polycomb repressive complex 2 tri-helical domain SET PF00856.28 KFP08972.1 - 4.7e-18 66.1 1.0 2e-17 64.1 0.3 2.5 2 1 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.8 KFP08972.1 - 1.7e-15 56.8 0.2 4e-15 55.6 0.2 1.7 1 0 0 1 1 1 1 WD repeat binding protein EZH2 preSET_CXC PF18264.1 KFP08972.1 - 7.8e-12 45.5 15.7 7.8e-12 45.5 15.7 4.4 4 1 0 4 4 4 1 CXC domain PIN PF01850.21 KFP08972.1 - 0.086 13.4 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 PIN domain Tubulin PF00091.25 KFP08973.1 - 4e-55 187.1 0.0 6.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP08973.1 - 9.2e-47 158.3 0.1 1.9e-46 157.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP08973.1 - 0.025 14.3 0.2 0.063 13.0 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 KFP08973.1 - 0.049 12.8 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin like HLH PF00010.26 KFP08975.1 - 6.7e-14 51.6 0.1 1.4e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain V_ATPase_I PF01496.19 KFP08976.1 - 1.3e-297 989.2 0.1 1.6e-297 988.9 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Tektin PF03148.14 KFP08977.1 - 0.026 13.3 17.6 0.014 14.1 5.7 2.0 2 0 0 2 2 2 0 Tektin family IMS_C PF11799.8 KFP08977.1 - 0.043 14.5 2.2 0.67 10.7 2.2 2.1 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain Big_3_3 PF13750.6 KFP08977.1 - 0.057 13.1 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DUF2277 PF10041.9 KFP08977.1 - 0.16 12.3 0.7 4.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) Ras PF00071.22 KFP08979.1 - 4.7e-53 179.1 1.2 7.1e-53 178.5 1.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP08979.1 - 4.8e-33 113.9 0.4 9.6e-33 113.0 0.4 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP08979.1 - 3.2e-10 39.7 0.7 4.4e-10 39.3 0.7 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP08979.1 - 1.3e-06 28.5 0.1 1.9e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP08979.1 - 8.3e-05 22.5 2.2 0.014 15.3 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP08979.1 - 0.00011 21.8 0.3 0.00021 20.9 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP08979.1 - 0.00073 19.4 2.8 0.0015 18.4 0.4 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KFP08979.1 - 0.00077 18.9 0.2 0.00097 18.5 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region HGTP_anticodon2 PF12745.7 KFP08979.1 - 0.021 14.4 0.6 0.03 13.8 0.6 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs FeoB_N PF02421.18 KFP08979.1 - 0.026 14.0 0.2 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B YwhD PF08741.10 KFP08979.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 YwhD family MMR_HSR1_Xtn PF16897.5 KFP08979.1 - 0.065 13.3 0.3 0.11 12.5 0.3 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain mRNA_cap_enzyme PF01331.19 KFP08980.1 - 1.2e-77 260.1 0.2 1.7e-77 259.6 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFP08980.1 - 6.8e-20 71.7 0.0 1.4e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 KFP08980.1 - 1.6e-10 40.9 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 KFP08980.1 - 2.7e-06 27.2 0.0 0.011 15.4 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Y_phosphatase PF00102.27 KFP08980.1 - 0.00033 20.3 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP08980.1 - 0.033 14.2 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFP08980.1 - 0.042 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4462 PF14692.6 KFP08982.1 - 0.19 11.3 0.7 0.34 10.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) 7tm_1 PF00001.21 KFP08983.1 - 2.1e-45 155.1 16.8 3.1e-45 154.5 16.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP08983.1 - 2e-12 47.1 16.9 2.9e-12 46.5 16.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP08983.1 - 1.1e-09 38.4 13.7 1.5e-05 24.9 6.2 2.5 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP08983.1 - 3.5e-07 30.1 9.5 3.5e-07 30.1 9.5 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx YlaC PF10777.9 KFP08983.1 - 0.037 13.9 3.4 0.1 12.4 0.3 2.6 3 0 0 3 3 3 0 Inner membrane protein YlaC MgtC PF02308.16 KFP08984.1 - 0.011 16.1 0.4 0.014 15.7 0.4 1.2 1 0 0 1 1 1 0 MgtC family DUF930 PF06059.12 KFP08984.1 - 0.059 13.9 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) PET10 PF17316.2 KFP08986.1 - 0.035 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 DUF885 PF05960.11 KFP08986.1 - 0.057 13.1 0.1 0.063 12.9 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ORC3_N PF07034.11 KFP08987.1 - 1.8e-128 428.3 7.4 1.8e-128 428.3 7.4 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFP08987.1 - 1.2e-30 106.4 0.1 1e-28 100.1 0.0 3.0 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal Endonuc-BsobI PF09194.10 KFP08987.1 - 0.054 12.7 0.2 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Restriction endonuclease BsobI Vac14_Fab1_bd PF12755.7 KFP08987.1 - 0.12 13.0 0.1 1 10.0 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region TAFH PF07531.14 KFP08987.1 - 0.13 12.4 2.6 2.4 8.3 0.1 3.3 2 1 0 2 2 2 0 NHR1 homology to TAF tRNA-synt_1d PF00750.19 KFP08988.1 - 9.8e-91 304.3 2.3 1.3e-90 303.9 2.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFP08988.1 - 6.9e-21 74.6 0.4 6.9e-21 74.6 0.4 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1g PF09334.11 KFP08988.1 - 0.0063 15.3 0.3 0.13 11.0 0.1 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (M) Nuc_sug_transp PF04142.15 KFP08989.1 - 9.8e-122 406.0 26.8 1.1e-121 405.8 26.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFP08989.1 - 0.034 14.3 33.7 0.67 10.1 8.1 3.0 2 1 0 2 2 2 0 EamA-like transporter family DUF202 PF02656.15 KFP08989.1 - 0.21 12.0 0.2 0.21 12.0 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) FAP206 PF12018.8 KFP08991.1 - 1.6e-101 339.5 7.9 3.6e-101 338.3 7.9 1.6 1 0 0 1 1 1 1 Domain of unknown function YHS PF04945.13 KFP08991.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 YHS domain DUF4407 PF14362.6 KFP08992.1 - 0.011 15.1 1.1 0.011 15.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KFP08992.1 - 1.3 9.0 4.9 1.9 8.5 1.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2258 PF10015.9 KFP08992.1 - 1.8 8.8 6.7 0.24 11.5 1.1 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) Exog_C PF18026.1 KFP08992.1 - 2.9 8.0 7.0 9.8 6.3 0.5 3.3 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain Connexin PF00029.19 KFP08993.1 - 3.7e-78 262.5 12.3 1.2e-44 152.9 0.2 2.0 1 1 1 2 2 2 2 Connexin zf-C2H2 PF00096.26 KFP08994.1 - 6.4e-16 57.8 95.3 0.0036 17.7 0.1 16.2 16 0 0 16 16 16 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP08994.1 - 5.8e-12 45.4 97.8 0.21 12.5 0.1 16.6 17 0 0 17 17 17 9 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP08994.1 - 5.3e-05 23.1 39.5 0.26 11.3 0.6 8.3 9 0 0 9 9 8 4 C2H2-type zinc finger zinc_ribbon_11 PF11682.8 KFP08994.1 - 0.0019 18.2 0.5 0.012 15.6 0.5 2.5 1 0 0 1 1 1 1 Probable zinc-ribbon Zn-C2H2_12 PF18112.1 KFP08994.1 - 0.0037 17.7 6.0 0.26 11.8 0.4 3.6 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf_C2H2_ZHX PF18387.1 KFP08994.1 - 0.048 13.3 1.3 0.36 10.5 0.1 3.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFP08994.1 - 0.14 11.9 9.5 1.6 8.6 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf_Hakai PF18408.1 KFP08994.1 - 0.17 11.6 24.9 0.56 10.0 0.1 6.3 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 KFP08994.1 - 0.23 11.8 47.8 2.8 8.3 2.4 10.4 9 2 2 11 11 11 0 C2H2-type zinc ribbon Zn_ribbon_SprT PF17283.2 KFP08994.1 - 0.29 11.1 5.4 0.76 9.7 1.7 3.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain FOXP-CC PF16159.5 KFP08994.1 - 0.45 11.2 45.8 3.3 8.4 0.0 12.2 9 2 3 13 13 13 0 FOXP coiled-coil domain RPA_C PF08784.11 KFP08994.1 - 6.2 7.5 8.7 0.39 11.4 0.7 3.4 2 1 1 3 3 2 0 Replication protein A C terminal Hormone_6 PF00236.18 KFP08995.1 - 6.7e-53 176.7 8.9 8e-53 176.4 8.9 1.1 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.17 KFP08995.1 - 0.07 13.4 8.9 0.13 12.6 8.9 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain 7tm_1 PF00001.21 KFP08996.1 - 1.4e-73 247.5 11.8 1.8e-73 247.1 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP08996.1 - 1.6e-08 34.5 17.5 2.7e-08 33.8 17.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP08996.1 - 4.6e-07 29.5 13.0 9.6e-07 28.4 13.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP08996.1 - 6.3e-05 22.8 12.8 0.00094 19.0 12.8 2.1 1 1 0 1 1 1 1 Olfactory receptor DUF3736 PF12540.8 KFP08997.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) RRM_1 PF00076.22 KFP08998.1 - 2e-45 152.5 1.3 8.6e-16 57.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFP08998.1 - 3.2e-33 113.5 0.3 1.9e-32 111.0 0.1 2.2 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_5 PF13893.6 KFP08998.1 - 6.3e-07 29.0 0.0 0.00027 20.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP08998.1 - 3e-06 27.2 0.3 0.92 9.7 0.0 4.3 3 2 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 KFP08998.1 - 7.7e-05 22.7 0.1 0.31 11.1 0.1 3.6 3 1 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 KFP08998.1 - 0.0039 17.0 0.1 0.081 12.8 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif Calcipressin PF04847.12 KFP08998.1 - 0.019 14.7 0.1 0.14 11.9 0.3 2.3 3 0 0 3 3 3 0 Calcipressin PHM7_cyt PF14703.6 KFP08998.1 - 0.02 15.1 2.4 7.5 6.8 0.1 4.3 3 2 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter PXA PF02194.15 KFP08999.1 - 7.9e-38 130.2 0.3 3e-37 128.4 0.3 2.1 1 0 0 1 1 1 1 PXA domain PX PF00787.24 KFP08999.1 - 2.2e-20 72.7 1.1 2.2e-20 72.7 1.1 2.9 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.12 KFP08999.1 - 2e-14 54.1 0.0 7.3e-14 52.3 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 KFP08999.1 - 1.2e-11 44.9 3.7 1.6e-11 44.5 2.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain dDENN PF03455.19 KFP08999.1 - 0.4 10.7 3.2 3.8 7.6 0.4 3.7 4 0 0 4 4 4 0 dDENN domain 5_nucleotid_C PF02872.18 KFP09000.1 - 1.1e-41 142.7 0.0 2e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KFP09000.1 - 0.016 15.7 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Pkinase PF00069.25 KFP09002.1 - 8.6e-64 215.4 0.0 1e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09002.1 - 9.3e-34 116.9 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP09002.1 - 3.6e-06 26.5 0.0 2e-05 24.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like WaaY PF06176.11 KFP09002.1 - 0.00066 19.4 0.2 0.29 10.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KFP09002.1 - 0.00076 18.9 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP09002.1 - 0.031 13.2 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFP09002.1 - 0.049 13.2 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP09002.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRAP PF15183.6 KFP09003.1 - 3.2e-34 116.8 0.1 4.9e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family Cyt-b5 PF00173.28 KFP09005.1 - 4.9e-24 84.3 0.0 1.4e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 KFP09005.1 - 5.7e-18 65.1 0.0 1.8e-17 63.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFP09005.1 - 6.3e-17 62.2 0.0 2.1e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CS PF04969.16 KFP09005.1 - 5e-07 30.6 3.1 5.8e-07 30.4 1.8 1.9 2 0 0 2 2 2 1 CS domain NAD_binding_6 PF08030.12 KFP09005.1 - 0.00048 20.3 0.0 0.0067 16.6 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain ANTH PF07651.16 KFP09006.1 - 6.5e-85 284.5 0.5 7.8e-85 284.2 0.5 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFP09006.1 - 7.1e-15 55.2 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 KFP09006.1 - 0.054 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain TALPID3 PF15324.6 KFP09006.1 - 3.3 5.2 7.8 5.6 4.5 7.8 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Trypsin PF00089.26 KFP09007.1 - 3.3e-11 43.4 0.0 7.3e-09 35.7 0.0 2.6 2 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KFP09007.1 - 4.8e-06 27.5 0.0 1e-05 26.5 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain LAP1C PF05609.12 KFP09007.1 - 0.0095 15.1 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF316 PF03761.15 KFP09007.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Malic_M PF03949.15 KFP09008.1 - 1.3e-101 339.2 0.5 1.6e-101 338.9 0.5 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFP09008.1 - 4.5e-81 271.0 0.0 7.2e-81 270.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PGM_PMM_I PF02878.16 KFP09009.1 - 7.5e-20 71.1 0.1 1.8e-08 34.2 0.0 3.5 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFP09009.1 - 2.3e-11 43.7 0.4 2.3e-11 43.7 0.4 2.5 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFP09009.1 - 0.00058 20.0 0.5 0.0016 18.6 0.5 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CinA_KH PF18146.1 KFP09009.1 - 0.015 15.5 2.0 0.5 10.5 0.1 2.9 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain DUF4385 PF14328.6 KFP09009.1 - 0.06 13.4 0.2 9.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4385) Terminase_2 PF03592.16 KFP09009.1 - 0.22 12.0 2.2 0.17 12.4 0.3 1.8 2 0 0 2 2 2 0 Terminase small subunit Sec63 PF02889.16 KFP09010.1 - 1.3e-19 70.4 3.3 5.2e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 KFP09010.1 - 3.1e-17 62.4 0.4 9.1e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain SLED PF12140.8 KFP09011.1 - 9.8e-35 119.5 0.4 1.4e-34 118.9 0.4 1.2 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFP09011.1 - 8.7e-15 54.9 0.1 1.8e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RBR PF17208.3 KFP09011.1 - 2.4e-12 47.4 7.7 5.6e-12 46.2 7.7 1.7 1 0 0 1 1 1 1 RNA binding Region SAM_2 PF07647.17 KFP09011.1 - 0.00064 19.8 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP09011.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SOBP PF15279.6 KFP09012.1 - 3.4e-91 307.2 39.9 3.4e-91 307.2 39.9 3.3 3 1 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.14 KFP09012.1 - 0.0033 17.3 12.2 0.17 11.8 1.5 2.7 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C6H2 PF15801.5 KFP09012.1 - 0.65 10.3 9.8 2 8.8 6.1 2.9 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding polyprenyl_synt PF00348.17 KFP09014.1 - 7.3e-20 71.1 0.1 1.1e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase VirK PF06903.12 KFP09014.1 - 0.0045 17.0 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 VirK protein BEN PF10523.9 KFP09015.1 - 3.2e-72 238.7 3.5 3.9e-21 75.1 0.0 4.5 4 0 0 4 4 4 4 BEN domain FAM176 PF14851.6 KFP09017.1 - 0.031 14.0 2.2 0.053 13.2 2.2 1.4 1 0 0 1 1 1 0 FAM176 family Amidase PF01425.21 KFP09019.1 - 1e-128 430.2 0.0 4.7e-128 428.0 0.0 1.7 1 1 0 1 1 1 1 Amidase ADH_zinc_N_2 PF13602.6 KFP09020.1 - 6.5e-24 85.5 0.0 9.9e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFP09020.1 - 2.7e-15 56.5 0.0 9.8e-15 54.7 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP09020.1 - 1.5e-08 34.5 0.0 6.9e-08 32.4 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KFP09020.1 - 0.0076 16.0 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 KFP09020.1 - 0.025 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 KFP09020.1 - 0.08 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 KFP09020.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Crystall PF00030.19 KFP09021.1 - 5.1e-126 411.1 1.4 2.5e-28 98.1 0.0 6.3 6 0 0 6 6 6 6 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFP09021.1 - 2.8e-17 62.7 6.6 0.054 13.7 0.1 8.6 5 3 2 8 8 8 5 Interleukin-4 inducing immunoglobulin-binding domain Ricin_B_lectin PF00652.22 KFP09021.1 - 5.4e-11 42.9 0.0 9.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KFP09021.1 - 0.00015 22.4 0.0 0.13 13.0 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I36 PF03995.13 KFP09021.1 - 0.031 14.2 0.5 9.4 6.2 0.0 4.7 6 0 0 6 6 6 0 Peptidase inhibitor family I36 APG5 PF04106.12 KFP09025.1 - 4.5e-61 206.3 0.6 5.8e-61 206.0 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 zf-H2C2_2 PF13465.6 KFP09026.1 - 3.3e-16 58.9 37.8 5.8e-07 29.7 0.6 5.5 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP09026.1 - 1.8e-11 43.8 32.2 1.8e-05 24.9 0.4 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type SET PF00856.28 KFP09026.1 - 2.2e-07 31.4 0.2 8.6e-07 29.5 0.2 1.9 1 1 0 1 1 1 1 SET domain zf-C2H2_4 PF13894.6 KFP09026.1 - 0.00048 20.7 35.7 0.012 16.4 0.5 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP09026.1 - 0.0051 16.8 0.7 0.0051 16.8 0.7 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger Spt46 PF17734.1 KFP09026.1 - 5.5 6.7 9.3 4.6 7.0 0.7 2.6 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 zf-met PF12874.7 KFP09026.1 - 5.9 7.4 26.2 0.21 12.0 0.9 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KFP09026.1 - 6.9 6.9 7.9 20 5.4 0.1 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Peptidase_S9_N PF02897.15 KFP09027.1 - 1.2e-143 478.9 0.0 1.4e-143 478.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KFP09027.1 - 3.8e-68 229.1 0.0 5.8e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFP09027.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase CSD PF00313.22 KFP09030.1 - 1e-17 63.7 0.1 2.2e-17 62.7 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 KFP09030.1 - 9.9e-09 34.9 13.8 6.8e-05 22.8 2.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFP09030.1 - 0.43 10.4 10.4 0.15 11.8 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFP09030.1 - 0.54 10.1 7.5 5.9 6.8 1.6 2.6 2 0 0 2 2 2 0 Zinc knuckle HECT PF00632.25 KFP09032.1 - 7.4e-92 308.1 0.1 4.2e-91 305.6 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 KFP09032.1 - 8.6e-35 119.2 1.8 9.2e-12 45.4 0.2 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09032.1 - 1.8e-33 114.4 3.5 3.7e-11 43.3 0.1 6.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP09032.1 - 1e-27 93.1 3.4 2e-05 24.6 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KFP09032.1 - 5.9e-27 92.9 11.3 1.5e-06 28.3 0.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KFP09032.1 - 3.9e-23 81.2 5.0 1.8e-07 31.3 0.1 4.0 2 1 0 3 3 3 3 Ankyrin repeats (many copies) RVT_1 PF00078.27 KFP09033.1 - 0.001 18.7 0.0 0.0029 17.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1949 PF09186.11 KFP09036.1 - 0.16 11.9 1.3 0.44 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DOCK_N PF16172.5 KFP09037.1 - 6e-114 380.9 1.6 6e-114 380.9 0.1 1.8 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 KFP09037.1 - 1.8e-99 333.8 9.8 1.8e-99 333.8 9.8 2.6 2 2 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP09037.1 - 2.5e-58 197.1 0.0 1.7e-57 194.4 0.0 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 KFP09037.1 - 3.9e-05 23.4 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09037.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP09037.1 - 0.00088 18.9 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain FliX PF10768.9 KFP09037.1 - 0.11 13.0 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 Class II flagellar assembly regulator DUF1539 PF07560.11 KFP09037.1 - 4 7.6 10.1 0.27 11.3 1.1 3.9 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1539) HSCB_C PF07743.13 KFP09037.1 - 5.6 7.5 9.4 9.9 6.7 0.0 4.6 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain FAM196 PF15265.6 KFP09038.1 - 5.2e-151 504.5 27.5 5.9e-151 504.3 27.5 1.0 1 0 0 1 1 1 1 FAM196 family Forkhead PF00250.18 KFP09039.1 - 7.7e-40 135.0 0.0 9.1e-40 134.8 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain SH2 PF00017.24 KFP09040.1 - 5.2e-14 52.1 0.1 9e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.17 KFP09040.1 - 7.9e-05 22.7 0.1 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SDA1 PF05285.12 KFP09040.1 - 0.52 9.7 5.3 0.77 9.1 5.3 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 KFP09040.1 - 0.79 9.8 6.2 1.3 9.1 6.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CaKB PF03185.15 KFP09041.1 - 5.4e-73 244.8 0.2 6.1e-73 244.7 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit EF-hand_7 PF13499.6 KFP09042.1 - 1.1e-23 83.4 2.2 1.7e-18 66.8 0.3 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP09042.1 - 5.6e-18 63.1 6.2 2.5e-07 29.8 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP09042.1 - 7.7e-16 56.6 5.5 0.00029 20.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP09042.1 - 9.5e-15 54.2 4.4 0.0002 21.1 0.0 3.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP09042.1 - 2e-12 46.0 4.1 2.9e-05 23.4 0.1 3.7 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 KFP09042.1 - 3.3e-06 27.4 1.3 0.00059 20.1 1.1 3.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP09042.1 - 0.0017 18.2 1.8 0.068 13.1 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP09042.1 - 0.0024 18.2 0.1 7.4 7.0 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_10 PF14788.6 KFP09042.1 - 0.036 13.9 0.4 4.2 7.3 0.0 2.8 3 0 0 3 3 3 0 EF hand EF-hand_2 PF09068.11 KFP09042.1 - 0.042 14.0 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 KFP09042.1 - 0.094 12.9 0.7 1.2 9.4 0.5 2.4 1 1 1 2 2 2 0 Dockerin type I domain His_kinase PF06580.13 KFP09042.1 - 0.11 12.9 0.1 0.34 11.2 0.1 1.9 1 1 1 2 2 2 0 Histidine kinase Troponin PF00992.20 KFP09042.1 - 0.14 12.5 0.1 0.4 11.0 0.1 1.8 1 1 1 2 2 2 0 Troponin Caleosin PF05042.13 KFP09042.1 - 0.32 10.9 3.5 6.2 6.7 0.1 2.9 2 1 0 2 2 2 0 Caleosin related protein Neur_chan_LBD PF02931.23 KFP09043.1 - 3.2e-46 157.5 0.1 3.2e-46 157.5 0.1 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP09043.1 - 3.5e-22 79.6 9.3 8.9e-21 75.0 4.3 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.16 KFP09044.1 - 5.1e-14 52.1 0.0 7.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP09044.1 - 1.8e-13 50.9 0.0 3.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.18 KFP09044.1 - 1.1e-06 29.2 20.8 1.1e-06 29.2 20.8 2.2 2 0 0 2 2 2 1 Insulin-like growth factor binding protein ig PF00047.25 KFP09044.1 - 1.1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.21 KFP09044.1 - 1.6e-05 24.8 3.7 1.6e-05 24.8 3.7 2.3 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP09044.1 - 0.00014 21.9 3.4 0.00014 21.9 3.4 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KFP09044.1 - 0.00019 21.6 0.0 0.00063 19.9 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP09044.1 - 0.0002 21.7 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain IBN_N PF03810.19 KFP09045.1 - 4.8e-10 39.2 0.2 4.8e-10 39.2 0.2 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Nucleoplasmin PF03066.15 KFP09046.1 - 1e-33 115.9 0.0 2.5e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain NPM1-C PF16276.5 KFP09046.1 - 3.2e-28 97.5 0.8 7e-28 96.4 0.8 1.6 1 0 0 1 1 1 1 Nucleophosmin C-terminal domain TFIIF_alpha PF05793.12 KFP09046.1 - 0.00013 20.7 17.2 0.00013 20.7 17.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 KFP09046.1 - 0.00016 21.2 13.6 0.0002 20.9 13.6 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KFP09046.1 - 0.0015 16.9 19.7 0.002 16.4 19.7 1.1 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.12 KFP09046.1 - 0.079 12.3 20.2 0.15 11.3 20.2 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KFP09046.1 - 0.55 8.5 16.2 0.77 8.0 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KFP09046.1 - 3.6 5.6 23.1 5.3 5.0 23.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 KFP09046.1 - 4.7 5.2 7.5 5.9 4.9 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Roughex PF06020.11 KFP09046.1 - 4.7 6.2 10.8 7.7 5.5 10.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SLAIN PF15301.6 KFP09046.1 - 5.6 6.1 13.7 27 3.8 13.2 2.0 1 1 0 1 1 1 0 SLAIN motif-containing family FGF PF00167.18 KFP09047.1 - 9.8e-43 145.2 0.1 1.3e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor WD40 PF00400.32 KFP09048.1 - 6.7e-40 134.4 17.9 6.7e-07 29.9 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFP09048.1 - 9.9e-26 89.4 2.3 2.1e-25 88.3 2.3 1.6 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 KFP09048.1 - 3.6e-11 43.2 2.7 0.0095 16.2 0.1 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KFP09048.1 - 1.1e-09 38.0 0.1 2.6e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP09048.1 - 1.4e-06 28.0 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFP09048.1 - 1.8e-06 27.5 0.1 0.0082 15.5 0.4 2.5 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFP09048.1 - 7.8e-05 21.5 10.3 0.095 11.3 0.2 4.5 3 2 3 6 6 6 2 Nucleoporin Nup120/160 DUF5046 PF16465.5 KFP09048.1 - 0.0092 15.5 0.2 0.91 8.9 0.2 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) eIF2A PF08662.11 KFP09048.1 - 0.022 14.7 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4508 PF14969.6 KFP09048.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF1513 PF07433.11 KFP09048.1 - 0.12 11.5 0.0 1.2 8.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Prot_ATP_ID_OB PF16450.5 KFP09048.1 - 0.14 12.1 0.2 15 5.7 0.0 3.2 2 1 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain eRF1_2 PF03464.15 KFP09049.1 - 1.4e-46 158.1 0.1 2.4e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFP09049.1 - 4.3e-39 133.5 0.3 9.3e-39 132.4 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFP09049.1 - 3.7e-18 65.8 0.0 7.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KFP09049.1 - 8.8e-11 42.2 0.1 1.3e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KFP09049.1 - 7.1e-09 36.0 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 KFP09049.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4825 PF16107.5 KFP09049.1 - 0.12 12.5 0.1 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4825) Vinculin PF01044.19 KFP09050.1 - 0 1038.2 37.6 4.3e-215 717.1 24.4 2.1 1 1 1 2 2 2 2 Vinculin family DUF4685 PF15737.5 KFP09050.1 - 0.17 12.3 1.7 33 4.9 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Peptidase_C5 PF00770.18 KFP09050.1 - 0.19 11.4 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus endoprotease LRR_8 PF13855.6 KFP09051.1 - 2.5e-48 161.7 53.4 5.5e-16 58.1 6.7 5.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP09051.1 - 5.2e-25 87.1 38.1 3.8e-06 27.1 1.1 6.3 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP09051.1 - 1.4e-21 76.7 0.1 6.1e-10 39.2 0.0 3.5 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP09051.1 - 9.5e-12 44.8 10.7 0.00021 20.9 0.4 3.6 1 1 0 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFP09051.1 - 3.4e-08 32.9 35.4 0.98 10.2 0.2 9.9 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 KFP09051.1 - 0.0096 15.9 41.7 4.5 7.6 0.1 10.1 10 0 0 10 10 10 3 Leucine Rich repeat LRRNT PF01462.18 KFP09051.1 - 0.019 14.6 2.0 0.019 14.6 2.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_2 PF07723.13 KFP09051.1 - 8.5 7.2 17.2 61 4.5 0.1 6.5 6 0 0 6 6 6 0 Leucine Rich Repeat Fes1 PF08609.10 KFP09052.1 - 2.6e-06 28.2 2.1 2.6e-06 28.2 2.1 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 CDC14 PF08045.11 KFP09052.1 - 0.0018 17.5 0.4 0.0018 17.5 0.4 2.4 2 1 0 2 2 2 1 Cell division control protein 14, SIN component MSP7_C PF12948.7 KFP09052.1 - 0.012 16.2 3.6 0.12 13.0 3.2 2.2 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain V-ATPase_H_C PF11698.8 KFP09052.1 - 0.021 14.9 3.6 0.18 11.9 0.5 2.9 2 1 1 3 3 3 0 V-ATPase subunit H DUF4704 PF15787.5 KFP09052.1 - 0.029 13.6 2.8 0.036 13.3 0.6 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4704) Atg14 PF10186.9 KFP09052.1 - 0.044 12.9 1.3 0.071 12.2 1.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HEAT_EZ PF13513.6 KFP09052.1 - 0.087 13.4 0.3 0.32 11.5 0.3 2.0 1 0 0 1 1 1 0 HEAT-like repeat DUF2120 PF09893.9 KFP09052.1 - 0.35 11.0 4.4 0.19 11.8 2.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) RRM_1 PF00076.22 KFP09053.1 - 2.6e-09 36.8 0.0 0.00033 20.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP09053.1 - 5.8e-07 29.2 0.1 0.0096 15.5 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTU2 PF10288.9 KFP09053.1 - 1.6 9.0 0.0 1.6 9.0 0.0 4.0 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_jaz PF12171.8 KFP09053.1 - 2.8 8.3 10.0 2.1 8.8 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PAM2 PF07145.15 KFP09054.1 - 1.6e-07 30.5 0.8 3.5e-07 29.4 0.8 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF3911 PF13050.6 KFP09054.1 - 0.0096 16.0 0.7 0.04 14.0 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3911) DUF1977 PF09320.11 KFP09055.1 - 6.2e-25 87.5 3.2 6.2e-25 87.5 3.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFP09055.1 - 9.1e-25 86.6 1.5 9.8e-25 86.5 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain GntP_permease PF02447.16 KFP09055.1 - 0.021 13.5 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 GntP family permease Sel1 PF08238.12 KFP09056.1 - 3.3e-23 81.6 20.0 2.8e-08 34.1 0.4 5.3 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.6 KFP09056.1 - 0.02 15.5 7.3 7 7.5 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP09056.1 - 2.1 8.6 15.4 5.4 7.4 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat SRI PF08236.11 KFP09057.1 - 0.9 9.8 8.0 0.46 10.7 2.8 2.3 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain RhoGAP PF00620.27 KFP09060.1 - 1.2e-45 155.1 0.1 2.5e-45 154.0 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain ArfGap PF01412.18 KFP09060.1 - 2e-23 82.7 0.0 5e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP09060.1 - 2.5e-18 66.5 0.0 6.4e-05 23.4 0.0 4.5 4 0 0 4 4 4 3 PH domain RA PF00788.23 KFP09060.1 - 5e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 KFP09060.1 - 6.4e-10 39.0 0.0 4.5e-09 36.3 0.1 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP09060.1 - 7.9e-07 29.4 0.1 2.3e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_6 PF15406.6 KFP09060.1 - 0.0013 19.0 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP09060.1 - 0.0085 16.5 0.4 0.47 10.9 0.2 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFP09060.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 KFP09060.1 - 0.04 14.0 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 PH domain 7tm_1 PF00001.21 KFP09061.1 - 1.6e-29 103.0 11.6 3.9e-29 101.8 11.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP09061.1 - 4.4e-05 23.0 7.7 5.7e-05 22.6 7.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP09061.1 - 0.015 14.6 4.1 0.039 13.2 0.5 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Pox_I5 PF04713.12 KFP09061.1 - 0.04 14.0 5.3 0.074 13.1 5.3 1.4 1 0 0 1 1 1 0 Poxvirus protein I5 COX7C PF02935.16 KFP09061.1 - 1.1 9.6 3.4 0.59 10.4 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc RELT PF12606.8 KFP09062.1 - 1.9e-23 81.2 1.7 3.6e-23 80.3 1.7 1.5 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 Hist_deacetyl PF00850.19 KFP09063.1 - 1.4e-77 261.2 0.1 2.1e-77 260.6 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4042 PF13251.6 KFP09064.1 - 1.7e-70 236.4 8.4 4.3e-70 235.1 0.1 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 KFP09064.1 - 4.7e-21 75.0 3.4 2.1e-06 28.0 0.0 7.2 5 3 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KFP09064.1 - 1.1e-18 65.7 12.2 0.00039 20.4 0.0 9.8 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 KFP09064.1 - 4.2e-14 52.7 17.7 0.0025 18.3 0.5 9.1 10 1 1 11 11 10 4 HEAT-like repeat Cnd1 PF12717.7 KFP09064.1 - 1.5e-06 28.4 6.6 0.05 13.7 0.1 4.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFP09064.1 - 0.00012 22.2 2.1 3.2 8.0 0.0 4.7 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFP09064.1 - 0.00061 18.5 11.4 0.22 10.0 0.4 4.7 4 2 1 5 5 5 3 Adaptin N terminal region HEAT_PBS PF03130.16 KFP09064.1 - 0.013 16.1 8.0 3.9 8.4 0.0 6.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat API5 PF05918.11 KFP09064.1 - 0.062 12.1 2.2 2.9 6.6 0.0 3.6 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) Arm PF00514.23 KFP09064.1 - 0.067 13.3 28.0 0.92 9.7 0.1 8.5 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat FANCI_S2 PF14676.6 KFP09064.1 - 0.19 12.1 4.3 6.4 7.1 0.1 3.3 3 0 0 3 3 3 0 FANCI solenoid 2 RasGEF_N_2 PF14663.6 KFP09064.1 - 0.24 11.8 4.5 11 6.5 0.1 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Dynein_light PF01221.18 KFP09065.1 - 5.2e-44 148.5 2.1 5.8e-44 148.3 2.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 KFP09065.1 - 0.067 12.7 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Ectatomin PF06457.11 KFP09065.1 - 0.15 12.0 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 Ectatomin zf-C2H2 PF00096.26 KFP09066.1 - 1.2e-16 60.2 56.2 0.0024 18.2 2.8 6.9 7 0 0 7 7 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP09066.1 - 1.3e-16 59.8 55.0 0.00039 21.0 1.0 6.9 7 0 0 7 7 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP09066.1 - 1.1e-12 47.8 58.8 5e-06 26.7 2.6 8.7 9 0 0 9 9 8 4 Zinc-finger double domain Spt20 PF12090.8 KFP09066.1 - 0.00014 21.6 32.7 0.00035 20.3 32.7 1.7 1 0 0 1 1 1 1 Spt20 family zf-C2H2_jaz PF12171.8 KFP09066.1 - 0.00015 22.0 23.5 0.19 12.1 0.7 6.4 6 0 0 6 6 5 1 Zinc-finger double-stranded RNA-binding EIF4E-T PF10477.9 KFP09066.1 - 0.008 15.1 18.0 0.0097 14.8 18.0 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E zf-C2H2_6 PF13912.6 KFP09066.1 - 0.0085 16.1 0.4 0.0085 16.1 0.4 7.6 9 0 0 9 9 6 4 C2H2-type zinc finger Suf PF05843.14 KFP09066.1 - 0.014 15.4 11.8 0.029 14.4 11.8 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EOS1 PF12326.8 KFP09066.1 - 0.015 15.3 8.8 0.035 14.0 8.8 1.6 1 0 0 1 1 1 0 N-glycosylation protein DDHD PF02862.17 KFP09066.1 - 0.015 15.5 10.9 0.022 14.9 8.9 2.1 2 0 0 2 2 2 0 DDHD domain DUF5427 PF10310.9 KFP09066.1 - 0.019 13.9 14.6 0.029 13.3 14.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) zf-Di19 PF05605.12 KFP09066.1 - 0.021 15.1 33.7 0.43 10.9 3.2 4.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding CPSF100_C PF13299.6 KFP09066.1 - 0.024 14.8 10.3 0.14 12.3 10.5 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-BED PF02892.15 KFP09066.1 - 0.031 14.3 2.7 0.031 14.3 2.7 6.8 5 2 2 7 7 7 0 BED zinc finger ABC2_membrane_2 PF12679.7 KFP09066.1 - 0.056 12.7 0.4 0.1 11.9 0.4 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein PAT1 PF09770.9 KFP09066.1 - 0.079 11.2 24.0 0.12 10.7 24.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 KFP09066.1 - 0.11 11.5 17.4 0.15 11.0 17.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf_C2H2_13 PF18508.1 KFP09066.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.2 3 0 0 3 3 2 0 Zinc finger domain Exonuc_VII_L PF02601.15 KFP09066.1 - 0.18 11.4 13.2 0.28 10.7 13.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4192 PF13830.6 KFP09066.1 - 0.2 11.7 1.6 0.3 11.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CSG2 PF16965.5 KFP09066.1 - 0.24 10.3 5.5 0.37 9.7 5.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 KFP09066.1 - 0.24 10.2 13.2 0.39 9.5 13.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 KFP09066.1 - 0.27 10.2 13.3 0.4 9.7 13.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KFP09066.1 - 0.32 9.1 11.4 0.44 8.6 11.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EMC3_TMCO1 PF01956.16 KFP09066.1 - 0.34 10.6 7.8 0.66 9.7 7.8 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Band_3_cyto PF07565.13 KFP09066.1 - 0.4 10.4 11.9 0.86 9.4 11.9 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AUX_IAA PF02309.16 KFP09066.1 - 0.41 10.5 9.3 0.89 9.4 9.3 1.5 1 0 0 1 1 1 0 AUX/IAA family Pinin_SDK_memA PF04696.13 KFP09066.1 - 0.42 10.7 26.5 0.79 9.8 26.5 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Folate_carrier PF01770.18 KFP09066.1 - 0.47 9.1 5.8 0.7 8.6 5.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 KFP09066.1 - 0.53 10.1 15.3 0.42 10.4 13.3 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SUFU_C PF12470.8 KFP09066.1 - 0.57 10.2 10.7 1.2 9.2 10.7 1.4 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain CobT PF06213.12 KFP09066.1 - 0.6 9.4 20.1 1.1 8.6 20.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 KFP09066.1 - 0.66 8.7 10.5 1.1 8.0 10.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EPL1 PF10513.9 KFP09066.1 - 0.69 10.3 16.2 0.019 15.3 9.0 2.1 3 0 0 3 3 1 0 Enhancer of polycomb-like Zip PF02535.22 KFP09066.1 - 0.73 9.0 7.8 1.5 8.0 7.8 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 KFP09066.1 - 0.73 9.2 15.3 1.1 8.6 15.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Paramyxo_ncap PF00973.19 KFP09066.1 - 0.89 8.4 13.6 1.4 7.8 13.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 KFP09066.1 - 1.1 8.0 18.2 1.7 7.3 18.2 1.3 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 KFP09066.1 - 1.2 9.5 9.9 2.9 8.3 9.9 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3537 PF12056.8 KFP09066.1 - 1.3 7.8 9.5 2.4 6.9 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) zf-C2H2_2 PF12756.7 KFP09066.1 - 1.4 9.3 0.0 1.4 9.3 0.0 6.6 2 1 3 6 6 5 0 C2H2 type zinc-finger (2 copies) DUF4407 PF14362.6 KFP09066.1 - 1.8 7.8 15.5 2.7 7.3 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4834 PF16118.5 KFP09066.1 - 1.9 9.5 17.3 5.5 8.0 17.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-C2H2_8 PF15909.5 KFP09066.1 - 2.3 8.6 17.1 0.32 11.3 3.4 3.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon Coilin_N PF15862.5 KFP09066.1 - 2.4 8.0 19.0 5.9 6.7 19.0 1.6 1 0 0 1 1 1 0 Coilin N-terminus zf_C2H2_ZHX PF18387.1 KFP09066.1 - 2.6 7.8 14.3 2.6 7.8 0.4 3.8 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain XRN_M PF17846.1 KFP09066.1 - 3.2 6.6 12.6 5 6.0 12.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain EIIBC-GUT_N PF03612.14 KFP09066.1 - 3.4 7.4 13.2 6.7 6.4 13.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.10 KFP09066.1 - 3.5 7.7 11.8 7.6 6.6 11.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PepSY_TM PF03929.16 KFP09066.1 - 3.6 7.2 6.7 6.7 6.3 6.7 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Membralin PF09746.9 KFP09066.1 - 3.7 6.5 9.8 5.2 6.0 9.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein TERB2 PF15101.6 KFP09066.1 - 4 7.4 21.6 7.1 6.6 21.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ThiD2 PF17792.1 KFP09066.1 - 4.3 7.8 8.1 9.3 6.7 8.1 1.5 1 0 0 1 1 1 0 ThiD2 family Ctr PF04145.15 KFP09066.1 - 4.7 7.8 8.3 12 6.5 8.3 1.7 1 0 0 1 1 1 0 Ctr copper transporter family V_ATPase_I PF01496.19 KFP09066.1 - 4.9 4.9 14.4 6.7 4.5 14.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4820 PF16091.5 KFP09066.1 - 5.6 6.3 14.8 0.94 8.8 9.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) WES_acyltransf PF03007.16 KFP09066.1 - 5.6 6.6 11.2 5.3 6.7 7.1 2.3 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Serinc PF03348.15 KFP09066.1 - 6.3 5.6 12.4 1.3 7.8 7.3 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-CHCC PF10276.9 KFP09066.1 - 6.4 6.9 14.4 45 4.2 0.1 5.6 6 0 0 6 6 5 0 Zinc-finger domain DUF4175 PF13779.6 KFP09066.1 - 6.5 4.5 33.4 8.9 4.1 33.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-FCS PF06467.14 KFP09066.1 - 7.1 6.7 29.8 2 8.4 3.0 6.6 5 2 2 7 7 7 0 MYM-type Zinc finger with FCS sequence motif DUF4746 PF15928.5 KFP09066.1 - 7.4 5.9 11.7 12 5.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MMR1 PF08505.10 KFP09066.1 - 7.4 6.8 28.0 8 6.7 22.5 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CCDC53 PF10152.9 KFP09066.1 - 7.9 6.9 18.5 0.21 12.0 11.0 2.1 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF1980 PF09323.10 KFP09066.1 - 8.2 6.3 13.2 19 5.1 13.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2722 PF10846.8 KFP09066.1 - 8.4 5.2 43.3 0.65 8.9 38.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FAM176 PF14851.6 KFP09066.1 - 9.9 5.8 12.2 19 4.9 12.2 1.4 1 0 0 1 1 1 0 FAM176 family CUE PF02845.16 KFP09067.1 - 1.2e-15 56.8 0.2 2.8e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 CUE domain MRP-S23 PF10484.9 KFP09068.1 - 9.6e-12 45.3 0.1 1e-11 45.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 RRM_1 PF00076.22 KFP09069.1 - 0.2 11.5 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TUDOR PF00567.24 KFP09070.1 - 7e-21 74.5 0.0 1.5e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 KFP09070.1 - 1.9e-11 43.6 0.0 4.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KFP09070.1 - 0.034 14.0 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 KH domain Agenet PF05641.12 KFP09070.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Agenet domain RII_binding_1 PF10522.9 KFP09070.1 - 0.32 11.3 2.0 0.95 9.9 2.0 1.9 1 0 0 1 1 1 0 RII binding domain EVI2A PF05399.11 KFP09071.1 - 5.7e-85 284.6 5.7 6.6e-85 284.4 5.7 1.0 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) TMEM154 PF15102.6 KFP09071.1 - 0.0013 18.7 2.1 0.0013 18.7 2.1 1.8 2 1 0 2 2 2 1 TMEM154 protein family SARAF PF06682.12 KFP09071.1 - 0.01 15.5 0.0 4 7.0 0.0 2.1 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis RIFIN PF02009.16 KFP09071.1 - 0.36 10.7 2.9 0.13 12.1 0.6 1.4 2 0 0 2 2 2 0 Rifin MGC-24 PF05283.11 KFP09071.1 - 1.7 9.1 10.9 5.4 7.5 10.9 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_4 PF12799.7 KFP09072.1 - 1e-14 54.4 28.3 0.00018 21.8 2.3 5.3 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP09072.1 - 1.8e-14 53.2 23.9 3.4e-09 36.3 0.9 4.2 2 1 0 3 3 3 3 Leucine rich repeat LRRNT PF01462.18 KFP09072.1 - 3.3e-08 33.0 3.5 7.9e-08 31.8 3.5 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP09072.1 - 2.7e-07 30.2 18.2 0.64 10.8 0.3 7.0 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP09072.1 - 0.016 14.7 6.6 0.28 10.6 0.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeat SERTA PF06031.13 KFP09072.1 - 0.14 11.8 0.7 0.94 9.2 0.2 2.6 2 0 0 2 2 2 0 SERTA motif LRR_6 PF13516.6 KFP09072.1 - 0.2 11.8 23.7 3.6 7.9 0.7 6.3 6 0 0 6 6 6 0 Leucine Rich repeat WD40 PF00400.32 KFP09073.1 - 7.1e-35 118.4 14.2 6.4e-08 33.1 0.0 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09073.1 - 6.6e-12 45.6 0.3 0.015 15.5 0.0 5.6 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP09073.1 - 1.6e-09 37.2 0.2 0.062 12.2 0.0 4.5 2 2 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein SOCS_box PF07525.16 KFP09073.1 - 3e-09 37.1 0.2 5.8e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 SOCS box eIF2A PF08662.11 KFP09073.1 - 8.9e-06 25.7 0.0 0.046 13.6 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFP09073.1 - 0.00046 19.6 0.0 2.3 7.5 0.0 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KFP09073.1 - 0.0027 16.4 0.4 0.15 10.7 0.1 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KFP09073.1 - 0.027 14.4 6.6 11 6.1 0.2 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KFP09073.1 - 0.05 12.1 0.2 4.2 5.8 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KFP09073.1 - 0.21 12.1 1.6 54 4.5 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain NO_synthase PF02898.15 KFP09074.1 - 1.3e-185 616.6 0.0 1.8e-185 616.2 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KFP09074.1 - 1.5e-68 230.7 0.0 2.5e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP09074.1 - 1.3e-42 145.4 0.0 3.1e-42 144.2 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFP09074.1 - 2.7e-22 79.5 0.0 9.5e-22 77.7 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFP09074.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF1400 PF07176.11 KFP09074.1 - 0.18 12.1 0.9 0.68 10.2 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) Complex1_LYR PF05347.15 KFP09075.1 - 4.3e-16 58.7 0.8 4.7e-16 58.6 0.8 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP09075.1 - 0.00044 20.9 0.8 0.00051 20.7 0.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFP09075.1 - 0.0012 19.4 0.0 0.0013 19.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Sigma70_r4 PF04545.16 KFP09075.1 - 0.012 15.1 0.8 3.1 7.4 0.1 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 DUF1320 PF07030.12 KFP09075.1 - 0.044 13.9 2.3 0.96 9.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) Pkinase PF00069.25 KFP09076.1 - 5e-64 216.2 0.0 8.2e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09076.1 - 4.7e-31 108.0 0.0 7.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP09076.1 - 6.6e-05 22.0 0.1 0.00014 20.9 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP09076.1 - 0.00015 20.7 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP09076.1 - 0.013 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KFP09076.1 - 0.033 14.1 4.9 0.15 11.9 4.9 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP09076.1 - 0.039 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2781 PF10914.8 KFP09077.1 - 1.3e-20 74.3 2.1 1.4e-20 74.2 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) IFT20 PF14931.6 KFP09078.1 - 5.4e-32 110.5 9.1 5.9e-32 110.3 9.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF1635 PF07795.11 KFP09078.1 - 0.27 11.1 3.5 0.3 10.9 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) BTB_2 PF02214.22 KFP09079.1 - 2.6e-20 72.6 0.0 4.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP09079.1 - 4.7e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP09079.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PH_RBD PF12068.8 KFP09080.1 - 4.1e-35 120.8 0.4 6.1e-33 113.7 0.0 3.3 2 1 0 2 2 2 1 Rab-binding domain (RBD) RUN PF02759.19 KFP09080.1 - 7.1e-32 110.2 0.0 2e-31 108.7 0.0 1.9 1 0 0 1 1 1 1 RUN domain RabGAP-TBC PF00566.18 KFP09080.1 - 8.1e-32 110.6 10.3 6.6e-30 104.4 6.0 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain zf-BED PF02892.15 KFP09080.1 - 0.0039 17.2 0.9 0.0093 16.0 0.1 2.1 2 0 0 2 2 2 1 BED zinc finger HLH PF00010.26 KFP09081.1 - 5.3e-13 48.7 2.2 5.3e-13 48.7 2.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sipho_Gp157 PF05565.11 KFP09081.1 - 0.0094 16.0 3.2 0.016 15.3 3.2 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 APG6_N PF17675.1 KFP09081.1 - 0.058 13.9 7.2 0.1 13.1 7.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF773 PF05600.12 KFP09081.1 - 0.56 8.9 9.5 0.026 13.3 4.1 1.4 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 LMBR1 PF04791.16 KFP09081.1 - 1 8.2 3.4 1.5 7.6 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 KFP09082.1 - 6.5e-62 204.0 17.0 1.3e-08 35.4 0.6 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09082.1 - 5.1e-16 58.8 2.7 0.045 14.1 0.0 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP09082.1 - 1.6e-12 46.9 11.3 0.013 14.2 0.0 6.4 2 2 4 7 7 7 4 Nucleoporin Nup120/160 LisH PF08513.11 KFP09082.1 - 5.9e-07 29.2 0.4 1.5e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KFP09082.1 - 3.5e-05 23.8 2.1 0.092 12.6 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KFP09082.1 - 5.7e-05 22.0 1.5 0.21 10.3 0.0 4.0 1 1 3 4 4 4 1 Nup133 N terminal like Ge1_WD40 PF16529.5 KFP09082.1 - 0.00059 18.9 9.6 1.4 7.8 0.3 5.1 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pox_A_type_inc PF04508.12 KFP09082.1 - 0.0016 18.2 0.1 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat LisH_2 PF16045.5 KFP09082.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 LisH Roc PF08477.13 KFP09082.1 - 0.047 13.9 0.7 1.6 8.9 0.1 3.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLU PF13236.6 KFP09083.1 - 8.2e-88 293.9 0.0 1.4e-87 293.2 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KFP09083.1 - 7.4e-60 202.0 0.0 1.8e-59 200.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KFP09083.1 - 4.6e-23 81.3 7.3 3.8e-10 39.9 0.3 3.8 1 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 KFP09083.1 - 2e-10 40.8 1.9 4.3e-10 39.8 0.1 2.6 2 1 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KFP09083.1 - 6.1e-08 32.3 5.9 9.5e-05 22.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP09083.1 - 2.1e-06 27.4 3.3 6.5e-06 25.7 0.2 2.3 2 0 0 2 2 2 1 MalT-like TPR region DUF727 PF05303.12 KFP09083.1 - 0.00026 21.0 0.0 0.00088 19.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Rad60-SLD PF11976.8 KFP09083.1 - 0.15 11.9 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TPR_2 PF07719.17 KFP09083.1 - 0.99 9.7 4.0 3.3 8.0 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP09083.1 - 3.5 7.9 6.0 4.3 7.6 0.2 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1151 PF06625.11 KFP09083.1 - 5 7.1 8.3 0.2 11.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) ANAPC_CDC26 PF10471.9 KFP09083.1 - 8.5 7.3 6.7 12 6.8 2.2 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Lipase_3 PF01764.25 KFP09084.1 - 5.6e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PTPA PF03095.15 KFP09086.1 - 9.1e-123 409.5 0.0 1.1e-122 409.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Carn_acyltransf PF00755.20 KFP09087.1 - 3.8e-206 686.3 0.0 4.3e-206 686.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PAP2 PF01569.21 KFP09088.1 - 5.2e-18 65.1 5.8 9.7e-18 64.2 5.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 KFP09088.1 - 0.0065 15.8 8.5 0.0065 15.8 8.5 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family WTF PF03303.13 KFP09088.1 - 0.033 13.9 0.7 0.042 13.6 0.7 1.2 1 0 0 1 1 1 0 WTF protein Phage_holin_3_1 PF05106.12 KFP09088.1 - 0.08 13.4 0.4 0.15 12.5 0.4 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) PSI_PsaJ PF01701.18 KFP09088.1 - 0.08 13.5 5.9 3.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ DUF212 PF02681.14 KFP09088.1 - 0.088 12.9 0.7 1.3 9.1 0.2 2.3 1 1 1 2 2 2 0 Divergent PAP2 family Miga PF10265.9 KFP09089.1 - 3.2e-229 762.4 0.2 3.7e-229 762.2 0.2 1.0 1 0 0 1 1 1 1 Mitoguardin DUF3824 PF12868.7 KFP09089.1 - 0.14 12.8 0.2 0.36 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) BAR PF03114.18 KFP09090.1 - 2.6e-66 223.7 2.3 5e-66 222.8 2.3 1.5 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFP09090.1 - 5.2e-11 42.2 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09090.1 - 1.7e-06 27.5 0.0 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP09090.1 - 1.8e-06 27.5 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFP09090.1 - 1.1e-05 24.7 0.6 1.4e-05 24.4 0.1 1.4 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP09090.1 - 0.00013 21.8 0.7 0.34 10.6 1.2 2.2 1 1 1 2 2 2 2 BAR domain of APPL family Nup188 PF10487.9 KFP09091.1 - 5e-230 766.0 0.5 5e-230 766.0 0.5 1.5 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 PhyH PF05721.13 KFP09093.1 - 1.1e-63 215.3 0.0 1.4e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pannexin_like PF12534.8 KFP09094.1 - 3.5e-145 483.5 4.1 4.5e-145 483.1 4.1 1.1 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFP09094.1 - 1.6e-30 104.6 39.3 3.3e-10 39.6 3.1 6.9 5 2 1 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFP09094.1 - 9.3e-28 95.8 49.8 1.3e-06 28.6 1.1 9.5 6 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP09094.1 - 2.7e-11 43.5 1.0 5e-06 26.5 0.6 3.9 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP09094.1 - 8.2e-08 31.9 18.7 6.7e-05 22.4 1.5 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KFP09094.1 - 0.04 14.0 0.3 0.04 14.0 0.3 8.4 9 0 0 9 9 9 0 Leucine Rich repeat Aminotran_1_2 PF00155.21 KFP09095.1 - 1.1e-57 195.9 0.0 1.2e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFP09095.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFP09095.1 - 0.0043 15.6 0.0 0.013 14.1 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltrn_RNA_3 PF02598.17 KFP09096.1 - 8.4e-108 360.2 0.0 1e-107 359.9 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase TTRAP PF14203.6 KFP09096.1 - 0.14 12.2 1.1 0.41 10.6 1.1 1.7 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein RabGAP-TBC PF00566.18 KFP09097.1 - 1.7e-37 129.2 4.3 1.6e-34 119.5 0.5 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain TFIID_20kDa PF03847.13 KFP09097.1 - 0.024 15.1 0.5 0.063 13.8 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Arm PF00514.23 KFP09098.1 - 1.5e-09 37.6 0.2 1.7 8.8 0.0 6.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KFP09098.1 - 0.009 16.0 2.1 2.3 8.1 0.8 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3361) zf-CCCH_6 PF18585.1 KFP09098.1 - 0.0093 15.8 0.2 2.5 8.1 0.0 3.9 3 0 0 3 3 3 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 HEAT_EZ PF13513.6 KFP09098.1 - 0.019 15.4 0.0 0.14 12.7 0.0 2.6 3 0 0 3 3 3 0 HEAT-like repeat SWC7 PF17330.2 KFP09098.1 - 0.05 13.7 0.6 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 LRR_8 PF13855.6 KFP09098.1 - 0.1 12.4 8.9 3.1 7.6 0.3 4.0 4 0 0 4 4 4 0 Leucine rich repeat Lentiviral_Tat PF02998.14 KFP09098.1 - 0.15 12.1 0.3 0.5 10.4 0.3 1.8 1 0 0 1 1 1 0 Lentiviral Tat protein LRR_4 PF12799.7 KFP09098.1 - 0.17 12.4 12.6 2.1 8.9 0.8 5.1 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP09098.1 - 0.29 11.9 6.1 40 5.3 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat DHHC PF01529.20 KFP09099.1 - 1.2e-30 106.4 14.7 2.7e-30 105.2 13.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Orf78 PF06024.12 KFP09099.1 - 0.16 12.3 1.6 3.1 8.1 1.8 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 KFP09099.1 - 0.95 9.1 7.4 0.081 12.5 0.7 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3974 PF13120.6 KFP09099.1 - 0.95 9.6 4.2 0.35 11.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Sigma_reg_N PF13800.6 KFP09099.1 - 1.3 9.4 3.7 24 5.3 2.9 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ac76 PF05814.11 KFP09099.1 - 1.3 9.1 5.8 0.18 11.8 0.3 2.2 3 0 0 3 3 3 0 Orf76 (Ac76) Pkinase PF00069.25 KFP09100.1 - 9.9e-59 198.8 0.0 1.7e-58 198.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09100.1 - 3.2e-34 118.4 0.0 5.4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFP09100.1 - 1.9e-32 111.2 11.4 2.6e-16 59.5 3.9 2.3 2 0 0 2 2 2 2 Hr1 repeat Kinase-like PF14531.6 KFP09100.1 - 8.1e-06 25.4 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.6 KFP09100.1 - 0.00015 21.9 6.1 0.0066 16.6 1.4 2.3 2 0 0 2 2 2 2 Up-regulated During Septation PL48 PF15903.5 KFP09100.1 - 0.043 12.8 1.6 3.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 TBCA PF02970.16 KFP09100.1 - 1.6 9.1 5.2 4.2 7.8 2.1 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF2564 PF10819.8 KFP09100.1 - 4.8 7.6 6.7 1.8 9.0 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) NAP PF00956.18 KFP09101.1 - 1.3e-37 129.5 14.4 9.1e-34 116.9 5.3 3.1 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 KFP09101.1 - 0.0032 17.4 2.6 0.0069 16.3 2.6 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Mst1_SARAH PF11629.8 KFP09101.1 - 0.064 13.4 0.8 0.17 12.0 0.8 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 ZapB PF06005.12 KFP09101.1 - 2 8.9 9.9 0.12 12.9 4.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Nore1-SARAH PF16517.5 KFP09101.1 - 3.7 7.5 8.6 0.13 12.2 1.3 2.5 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain WD40 PF00400.32 KFP09102.1 - 5e-11 43.0 10.9 0.66 10.9 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09102.1 - 0.00027 21.2 0.1 7.5 6.9 0.0 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Imm71 PF15602.6 KFP09102.1 - 0.095 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 71 GYF_2 PF14237.6 KFP09102.1 - 0.5 10.2 2.6 3.2 7.6 0.1 3.1 3 1 1 4 4 4 0 GYF domain 2 GLE1 PF07817.13 KFP09103.1 - 4.2e-89 298.1 0.0 8.3e-89 297.1 0.0 1.5 1 0 0 1 1 1 1 GLE1-like protein DUF4004 PF13171.6 KFP09103.1 - 0.0039 17.4 3.5 0.15 12.3 1.3 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4004) Par3_HAL_N_term PF12053.8 KFP09104.1 - 0.0024 18.0 1.8 0.12 12.6 0.2 3.4 2 0 0 2 2 2 1 N-terminal of Par3 and HAL proteins HMMR_N PF15905.5 KFP09104.1 - 0.0037 16.8 22.7 0.0037 16.8 22.7 5.6 1 1 3 5 5 5 2 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 KFP09104.1 - 0.007 16.5 9.6 0.007 16.5 9.6 9.1 1 1 6 9 9 9 4 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KFP09104.1 - 0.024 15.1 4.6 0.024 15.1 4.6 12.3 1 1 8 9 9 9 0 Cell division protein ZapB GST_N_3 PF13417.6 KFP09105.1 - 1.5e-12 47.7 0.6 1.6e-11 44.5 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KFP09105.1 - 3e-10 40.2 0.1 7.3e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KFP09105.1 - 3.6e-09 36.8 0.1 1.5e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP09105.1 - 2.5e-06 27.4 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFP09105.1 - 6.6e-05 23.6 0.0 0.00017 22.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 KFP09105.1 - 0.00041 20.6 0.0 0.00092 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP09105.1 - 0.00045 20.4 0.1 0.00095 19.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP09105.1 - 0.01 16.0 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Urocanase PF01175.18 KFP09105.1 - 0.036 13.7 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Urocanase Rossmann-like domain SNARE_assoc PF09335.11 KFP09105.1 - 0.079 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF668 PF05003.12 KFP09105.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF668) UPF0184 PF03670.13 KFP09106.1 - 3.1e-24 85.2 4.2 3.7e-24 84.9 4.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) NYD-SP28 PF14772.6 KFP09106.1 - 0.0024 17.9 2.9 0.0032 17.5 2.9 1.1 1 0 0 1 1 1 1 Sperm tail PhaP_Bmeg PF09602.10 KFP09106.1 - 0.0027 17.7 0.6 0.0031 17.5 0.6 1.1 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) EzrA PF06160.12 KFP09106.1 - 0.0042 15.3 1.4 0.0042 15.3 1.4 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA zf-C2H2_jaz PF12171.8 KFP09107.1 - 8.6e-05 22.7 0.5 8.6e-05 22.7 0.5 4.8 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP09107.1 - 0.0016 18.8 29.3 0.0026 18.1 7.2 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type AKAP95 PF04988.12 KFP09107.1 - 0.0057 16.9 13.7 0.009 16.3 10.2 2.2 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) Myc_N PF01056.18 KFP09107.1 - 0.0097 15.8 2.1 0.0097 15.8 2.1 2.0 2 0 0 2 2 2 1 Myc amino-terminal region zf-C2H2_4 PF13894.6 KFP09107.1 - 0.056 14.3 1.1 0.056 14.3 1.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP09107.1 - 0.1 13.0 25.8 0.056 13.8 1.9 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) THAP PF05485.12 KFP09107.1 - 3.6 8.6 11.8 0.52 11.3 7.1 2.1 2 0 0 2 2 2 0 THAP domain Swi5 PF07061.11 KFP09108.1 - 2.9e-24 84.9 1.9 3.4e-24 84.7 1.9 1.1 1 0 0 1 1 1 1 Swi5 APG6_N PF17675.1 KFP09108.1 - 0.00066 20.2 3.8 0.00078 20.0 3.8 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KFP09108.1 - 0.015 15.5 0.4 0.018 15.3 0.4 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 KFP09108.1 - 0.016 15.6 5.7 0.029 14.8 5.7 1.5 1 1 0 1 1 1 0 Cell division protein ZapB E2F_CC-MB PF16421.5 KFP09108.1 - 0.045 14.1 0.6 0.052 13.9 0.6 1.1 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DUF5338 PF17273.2 KFP09108.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5338) LINES_C PF14695.6 KFP09108.1 - 0.26 10.8 1.3 15 5.1 0.1 2.5 3 0 0 3 3 3 0 Lines C-terminus DivIC PF04977.15 KFP09108.1 - 0.39 10.5 4.8 0.64 9.8 4.3 1.6 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KFP09108.1 - 0.86 9.8 3.5 1.6 8.9 3.4 1.5 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KFP09108.1 - 2.3 8.4 7.8 1.7 8.8 5.0 1.9 2 0 0 2 2 2 0 Basic region leucine zipper TruB_N PF01509.18 KFP09109.1 - 4.7e-19 69.2 0.0 7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFP09109.1 - 0.0023 18.1 0.1 0.0089 16.2 0.1 2.1 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Coq4 PF05019.13 KFP09110.1 - 7.1e-97 323.1 0.0 8.1e-97 322.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rnk_N PF14760.6 KFP09110.1 - 0.029 14.9 0.1 0.071 13.6 0.1 1.7 1 0 0 1 1 1 0 Rnk N-terminus Urm1 PF09138.11 KFP09111.1 - 1e-37 128.4 0.0 1.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KFP09111.1 - 0.00099 19.7 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family Torsin PF06309.11 KFP09112.1 - 5.2e-38 130.0 0.1 1.3e-37 128.7 0.0 1.7 2 0 0 2 2 2 1 Torsin AAA_2 PF07724.14 KFP09112.1 - 0.00056 20.1 0.0 0.002 18.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ResIII PF04851.15 KFP09112.1 - 0.0036 17.3 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 KFP09112.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP09112.1 - 0.048 13.9 0.1 6.2 7.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 KFP09112.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 KFP09113.1 - 1e-63 215.2 0.0 1.2e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09113.1 - 5.2e-28 98.0 0.0 6.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP09113.1 - 1.2e-05 24.5 0.1 1.5e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP09113.1 - 0.02 14.2 0.1 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KFP09113.1 - 0.04 12.7 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KFP09113.1 - 0.88 9.1 4.1 0.59 9.7 1.2 2.1 2 1 0 2 2 2 0 RIO1 family Mur_ligase_M PF08245.12 KFP09114.1 - 0.033 14.2 0.0 1.5 8.8 0.0 2.2 1 1 1 2 2 2 0 Mur ligase middle domain Mur_ligase_C PF02875.21 KFP09114.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Zona_pellucida PF00100.23 KFP09115.1 - 1.8e-07 31.3 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DPM2 PF07297.12 KFP09116.1 - 7.4e-20 71.0 0.4 8.1e-20 70.9 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TMEM154 PF15102.6 KFP09116.1 - 0.0098 15.8 0.3 0.011 15.6 0.3 1.0 1 0 0 1 1 1 1 TMEM154 protein family S1FA PF04689.13 KFP09116.1 - 0.015 15.5 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 DNA binding protein S1FA LAX PF15681.5 KFP09116.1 - 0.053 12.3 0.4 0.061 12.1 0.4 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X Spem1 PF15670.5 KFP09116.1 - 0.062 12.9 0.1 0.067 12.8 0.1 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 NT-C2 PF10358.9 KFP09117.1 - 6.5e-30 103.8 0.0 1.5e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.27 KFP09118.1 - 7.8e-74 243.7 2.0 5.4e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFP09118.1 - 1.3e-14 54.3 2.4 8.2e-11 42.2 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP09118.1 - 9.5e-14 49.9 2.9 0.0014 18.1 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP09118.1 - 7.7e-12 44.1 3.4 0.00029 20.5 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP09118.1 - 5.3e-08 32.6 1.7 0.0051 16.6 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP09118.1 - 1.5e-06 27.4 2.7 0.0022 17.4 0.1 3.3 3 1 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 KFP09118.1 - 0.00062 19.6 0.9 1.2 9.1 0.0 3.5 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFP09118.1 - 0.0018 18.6 0.7 0.0038 17.5 0.7 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP09118.1 - 0.1 12.6 2.9 0.9 9.5 0.2 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1002 PF06207.11 KFP09118.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF2624 PF11116.8 KFP09118.1 - 0.13 13.1 0.0 0.28 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) ApoM PF11032.8 KFP09119.1 - 2.5e-10 40.3 0.0 2.9e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 ApoM domain Lipocalin PF00061.23 KFP09119.1 - 6.6e-08 32.9 0.0 9.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Thioredoxin_13 PF18401.1 KFP09119.1 - 0.05 13.5 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Laminin_G_2 PF02210.24 KFP09120.1 - 6.2e-06 26.8 0.1 9.1e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFP09120.1 - 9.2e-05 22.6 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GH131_N PF18271.1 KFP09120.1 - 0.002 17.8 0.1 0.0026 17.5 0.1 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Laminin_EGF PF00053.24 KFP09121.1 - 1.1e-34 118.3 83.6 2.1e-10 40.6 15.4 5.3 4 1 1 5 5 5 5 Laminin EGF domain TMEM154 PF15102.6 KFP09121.1 - 0.0035 17.2 0.3 0.0056 16.6 0.3 1.2 1 0 0 1 1 1 1 TMEM154 protein family Ephrin_rec_like PF07699.13 KFP09121.1 - 0.014 15.2 6.9 0.014 15.2 6.9 6.6 2 2 4 6 6 6 0 Putative ephrin-receptor like DUF3262 PF11660.8 KFP09121.1 - 0.072 13.5 0.5 0.14 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Stevor PF17410.2 KFP09121.1 - 0.14 11.7 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MACPF PF01823.19 KFP09123.1 - 3.8e-07 30.4 0.1 1.4e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain RhoGAP-FF1 PF16512.5 KFP09123.1 - 0.098 13.3 0.1 0.81 10.4 0.1 2.4 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain NHL PF01436.21 KFP09124.1 - 2.5e-31 106.1 2.1 1e-05 25.3 0.0 5.9 5 0 0 5 5 5 5 NHL repeat zf-RING_UBOX PF13445.6 KFP09124.1 - 3.3e-10 39.8 7.4 3.3e-10 39.8 7.4 2.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP09124.1 - 5.4e-09 36.2 9.2 5.4e-09 36.2 9.2 3.1 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP09124.1 - 4.7e-07 29.7 9.1 4.7e-07 29.7 9.1 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP09124.1 - 2.6e-06 27.2 10.4 2.6e-06 27.2 10.4 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KFP09124.1 - 3.6e-05 23.8 3.6 3.6e-05 23.8 3.6 3.2 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_4 PF15227.6 KFP09124.1 - 0.00012 22.2 8.6 0.00012 22.2 8.6 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFP09124.1 - 0.00013 21.7 9.7 0.00013 21.7 9.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KFP09124.1 - 0.00014 21.8 1.0 0.00014 21.8 1.0 2.3 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KFP09124.1 - 0.00035 20.3 5.8 0.00035 20.3 5.8 2.7 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP09124.1 - 0.00094 19.0 9.8 0.00094 19.0 9.8 3.9 4 1 1 5 5 4 1 Prokaryotic RING finger family 4 SGL PF08450.12 KFP09124.1 - 0.0022 17.6 0.0 12 5.4 0.0 3.8 2 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Borrelia_lipo_1 PF05714.11 KFP09124.1 - 0.035 13.9 0.2 0.058 13.2 0.2 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein zf-RING_11 PF17123.5 KFP09124.1 - 0.067 12.9 6.7 0.23 11.2 6.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger OmpH PF03938.14 KFP09124.1 - 0.21 11.9 3.1 0.33 11.3 3.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FYVE PF01363.21 KFP09124.1 - 0.63 10.2 26.0 0.44 10.7 7.9 3.1 2 1 1 3 3 2 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.7 KFP09124.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.5 4 0 0 4 4 3 0 Transposase zinc-ribbon domain CEBP_ZZ PF16366.5 KFP09124.1 - 1.5 9.1 11.5 3.4 8.0 1.5 3.5 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Rad50_zn_hook PF04423.14 KFP09124.1 - 3.8 7.4 7.1 1 9.2 0.3 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif Sushi PF00084.20 KFP09125.1 - 2e-22 79.5 47.7 2e-08 34.7 2.1 8.5 7 1 1 8 8 8 4 Sushi repeat (SCR repeat) Laminin_G_3 PF13385.6 KFP09125.1 - 2.6e-21 76.4 0.0 5.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_M43 PF05572.13 KFP09125.1 - 6.1e-08 32.7 0.8 2.2e-07 30.9 0.1 2.4 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Notch PF00066.17 KFP09125.1 - 0.0004 20.8 5.0 0.0004 20.8 5.0 6.8 6 0 0 6 6 6 3 LNR domain Reprolysin_3 PF13582.6 KFP09125.1 - 0.005 17.3 0.2 0.013 16.0 0.2 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP09125.1 - 0.074 12.7 0.1 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like fn3 PF00041.21 KFP09125.1 - 0.21 12.0 2.2 20 5.6 0.2 3.4 3 0 0 3 3 3 0 Fibronectin type III domain Peptidase_M10 PF00413.24 KFP09125.1 - 0.64 9.9 1.9 1.7 8.5 1.9 1.6 1 0 0 1 1 1 0 Matrixin Keratin PF02422.16 KFP09126.1 - 2.9e-28 97.4 11.3 3.1e-28 97.3 11.3 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP09126.1 - 0.037 14.3 2.2 0.043 14.1 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) S_100 PF01023.19 KFP09128.1 - 9e-20 70.1 0.2 1.6e-19 69.3 0.2 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain Mer2 PF09074.10 KFP09128.1 - 0.00055 19.8 5.2 0.00068 19.5 5.2 1.1 1 0 0 1 1 1 1 Mer2 EF-hand_1 PF00036.32 KFP09128.1 - 0.0011 18.4 0.7 0.003 17.0 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP09128.1 - 0.0028 18.0 0.6 0.005 17.3 0.6 1.5 1 1 0 1 1 1 1 EF-hand domain pair DEK_C PF08766.11 KFP09128.1 - 0.0052 16.7 0.6 0.01 15.8 0.6 1.4 1 0 0 1 1 1 1 DEK C terminal domain EF-hand_6 PF13405.6 KFP09128.1 - 0.13 12.2 0.7 11 6.2 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain S_100 PF01023.19 KFP09130.1 - 1e-08 34.7 0.1 1.5e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_5 PF13202.6 KFP09130.1 - 1.4e-05 24.3 0.5 0.00021 20.6 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFP09130.1 - 2.1e-05 23.8 0.3 0.0011 18.3 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP09130.1 - 4.8e-05 23.7 0.1 7.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP09130.1 - 0.0028 17.5 0.3 0.0049 16.7 0.3 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP09130.1 - 0.0049 16.7 0.1 0.86 9.7 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain S_100 PF01023.19 KFP09131.1 - 4.8e-14 51.8 0.1 7.4e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP09131.1 - 0.057 13.0 0.2 16 5.4 0.0 2.5 2 0 0 2 2 2 0 EF hand S_100 PF01023.19 KFP09132.1 - 3.5e-22 77.8 1.5 5.1e-22 77.3 1.5 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 KFP09132.1 - 1.3e-07 30.6 0.5 4.2e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP09132.1 - 1.4e-06 28.6 0.2 1.9e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP09132.1 - 8.9e-05 21.8 2.5 0.0016 17.8 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP09132.1 - 0.00019 21.1 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP09132.1 - 0.016 15.1 0.9 0.052 13.4 0.7 1.9 1 1 1 2 2 2 0 EF-hand domain pair Sigma54_CBD PF04963.13 KFP09132.1 - 0.054 13.3 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain EF-hand_4 PF12763.7 KFP09132.1 - 0.06 13.3 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DEK_C PF08766.11 KFP09132.1 - 0.11 12.5 0.4 0.18 11.8 0.4 1.5 1 1 0 1 1 1 0 DEK C terminal domain Snapin_Pallidin PF14712.6 KFP09133.1 - 1.1e-17 64.2 2.8 1.4e-17 63.9 2.8 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF4686 PF15742.5 KFP09133.1 - 0.048 12.8 2.3 0.054 12.6 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DZF PF07528.14 KFP09134.1 - 6.6e-96 320.7 0.0 8.6e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 DZF domain SMODS PF18144.1 KFP09134.1 - 0.041 14.1 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 KFP09134.1 - 0.11 12.8 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain Ints3 PF10189.9 KFP09135.1 - 6.4e-73 244.7 0.7 6.4e-73 244.7 0.7 1.8 2 0 0 2 2 2 1 Integrator complex subunit 3 Aconitase_B_N PF11791.8 KFP09135.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain TORC_M PF12885.7 KFP09136.1 - 2e-48 164.3 17.0 1.6e-34 119.1 10.5 3.1 3 0 0 3 3 3 3 Transducer of regulated CREB activity middle domain CTD_bind PF04818.13 KFP09137.1 - 1.6e-17 64.0 2.0 2.2e-17 63.6 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 KFP09137.1 - 1.2e-07 32.0 0.6 1.2e-07 32.0 0.6 1.9 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Acetyltransf_11 PF13720.6 KFP09137.1 - 0.092 13.2 0.1 12 6.4 0.0 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FadA PF09403.10 KFP09137.1 - 0.91 10.0 5.3 11 6.6 0.3 3.3 2 1 1 3 3 3 0 Adhesion protein FadA DUF1631 PF07793.11 KFP09137.1 - 1.2 7.5 5.9 2.1 6.7 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PRP3 PF08572.10 KFP09138.1 - 2.4e-80 269.5 6.5 2.4e-80 269.5 6.5 3.1 3 1 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFP09138.1 - 1.5e-48 164.6 1.8 1.5e-48 164.6 1.8 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PWI PF01480.17 KFP09138.1 - 1.9e-13 50.5 0.0 5.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 PWI domain TPX2 PF06886.11 KFP09138.1 - 0.058 13.6 0.4 0.058 13.6 0.4 5.8 6 0 0 6 6 6 0 Targeting protein for Xklp2 (TPX2) UPF0767 PF15990.5 KFP09138.1 - 8 6.7 6.3 7.7 6.7 0.8 3.0 2 0 0 2 2 2 0 UPF0767 family ig PF00047.25 KFP09139.1 - 1.1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP09139.1 - 3.7e-07 30.1 0.0 7.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP09139.1 - 7.1e-07 29.7 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP09139.1 - 3.1e-05 24.1 0.1 0.0029 17.8 0.1 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP09139.1 - 0.0043 17.4 0.0 0.0092 16.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP09139.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain DUF719 PF05334.13 KFP09140.1 - 2.8e-71 239.6 2.7 2.8e-71 239.6 2.7 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF719) RLL PF10036.9 KFP09140.1 - 0.062 13.1 5.3 0.21 11.4 5.1 1.9 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein LON_substr_bdg PF02190.16 KFP09141.1 - 3.2e-21 76.2 0.0 4.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFP09141.1 - 2.2e-10 40.2 14.7 9.3e-10 38.2 14.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP09141.1 - 2.2e-09 37.0 10.1 5.8e-09 35.7 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP09141.1 - 3.9e-07 29.8 16.7 5.6e-07 29.3 14.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP09141.1 - 4.3e-07 30.2 14.3 4.3e-07 30.2 14.3 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP09141.1 - 5.3e-07 29.6 10.6 6.8e-06 26.0 10.7 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP09141.1 - 2.1e-06 27.6 13.5 7.4e-06 25.8 13.5 2.0 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP09141.1 - 7.9e-06 25.6 11.1 2e-05 24.4 11.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP09141.1 - 3.8e-05 23.8 10.5 0.00017 21.7 10.5 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFP09141.1 - 0.00065 19.8 7.3 0.0016 18.5 7.3 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFP09141.1 - 0.0021 18.3 11.4 0.0061 16.8 11.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 KFP09141.1 - 0.0074 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 KFP09141.1 - 0.097 12.6 10.4 0.063 13.1 8.1 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFP09141.1 - 0.15 12.1 3.1 1.4 9.0 2.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFP09141.1 - 1.1 9.1 12.2 0.056 13.2 5.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFP09141.1 - 1.6 8.6 7.6 4.4 7.2 5.9 2.8 2 0 0 2 2 2 0 RING-like zinc finger ANF_receptor PF01094.28 KFP09143.1 - 6.6e-69 232.7 0.0 9.8e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP09143.1 - 1.4e-59 200.2 0.0 2.2e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP09143.1 - 1.1e-44 151.3 0.0 3e-44 149.9 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP09143.1 - 3.8e-24 85.4 0.0 7.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF659 PF04937.15 KFP09143.1 - 0.0038 17.1 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Ion_trans_2 PF07885.16 KFP09143.1 - 2.8 8.0 7.1 4.7 7.2 0.1 3.6 3 0 0 3 3 3 0 Ion channel 7tm_1 PF00001.21 KFP09146.1 - 3.2e-51 174.2 17.5 4.8e-51 173.6 17.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP09146.1 - 4e-10 39.5 16.4 8.5e-10 38.4 16.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP09146.1 - 1.8e-05 24.2 16.0 0.00045 19.6 16.0 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFP09146.1 - 0.00016 21.4 24.2 0.00033 20.4 21.5 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP09146.1 - 0.00055 19.8 14.9 0.0035 17.1 14.9 2.0 1 1 0 1 1 1 1 Olfactory receptor Sigma_reg_N PF13800.6 KFP09146.1 - 8.4 6.8 6.8 9.1 6.7 0.3 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Neur_chan_LBD PF02931.23 KFP09149.1 - 1e-53 182.0 0.0 1.3e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP09149.1 - 2.4e-40 139.1 1.0 9.5e-34 117.5 0.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region NTF2 PF02136.20 KFP09150.1 - 2.2e-30 105.7 0.4 3.8e-30 104.9 0.4 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFP09150.1 - 1.7e-13 50.1 0.0 3.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP09150.1 - 0.00012 22.1 0.0 0.00065 19.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif HMA PF00403.26 KFP09151.1 - 2.8e-10 40.5 0.1 3.2e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain RXLR_WY PF18634.1 KFP09151.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain SPARC_Ca_bdg PF10591.9 KFP09152.1 - 3.6e-41 140.0 0.6 8.4e-41 138.8 0.6 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.21 KFP09152.1 - 1.5e-15 56.9 7.3 1.3e-14 53.9 4.9 2.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP09152.1 - 3.8e-12 46.1 2.6 3.8e-12 46.1 2.6 3.0 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFP09152.1 - 5.2e-09 36.1 9.5 5.2e-09 36.1 9.5 2.2 3 0 0 3 3 3 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.32 KFP09152.1 - 0.024 14.2 0.2 0.2 11.3 0.1 2.5 2 1 0 2 2 2 0 EF hand hEGF PF12661.7 KFP09152.1 - 0.035 14.7 3.2 0.12 13.0 3.2 2.0 1 1 0 1 1 1 0 Human growth factor-like EGF DUF4801 PF16059.5 KFP09152.1 - 0.049 13.6 8.0 0.13 12.2 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) Cadherin PF00028.17 KFP09153.1 - 0 1586.6 42.7 1e-21 77.2 0.0 33.8 34 0 0 34 34 34 33 Cadherin domain Cadherin_2 PF08266.12 KFP09153.1 - 3e-20 71.8 0.0 0.29 11.0 0.1 17.6 22 0 0 22 22 22 2 Cadherin-like Cadherin_3 PF16184.5 KFP09153.1 - 5.9e-19 68.1 48.4 0.054 13.5 0.1 19.7 23 0 0 23 23 22 6 Cadherin-like Laminin_G_2 PF02210.24 KFP09153.1 - 1.7e-18 67.4 0.2 7e-18 65.4 0.2 2.2 1 0 0 1 1 1 1 Laminin G domain RET_CLD1 PF17756.1 KFP09153.1 - 8.8e-15 55.1 0.0 0.24 11.7 0.0 13.6 16 1 1 17 17 17 1 RET Cadherin like domain 1 Laminin_G_1 PF00054.23 KFP09153.1 - 4.7e-12 46.3 0.0 2.1e-11 44.2 0.0 2.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFP09153.1 - 3.1e-09 37.0 32.3 6.1e-05 23.2 9.2 3.6 3 0 0 3 3 3 2 EGF-like domain Laminin_G_3 PF13385.6 KFP09153.1 - 0.0013 19.0 0.3 0.018 15.2 0.1 3.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_4 PF17803.1 KFP09153.1 - 0.029 15.0 104.4 0.11 13.2 1.1 19.5 21 0 0 21 21 19 0 Bacterial cadherin-like domain hEGF PF12661.7 KFP09153.1 - 0.061 14.0 25.5 0.076 13.7 4.5 3.4 3 0 0 3 3 3 0 Human growth factor-like EGF FlgD_ig PF13860.6 KFP09153.1 - 0.091 12.6 0.0 0.99 9.3 0.0 3.1 1 0 0 1 1 1 0 FlgD Ig-like domain EGF_2 PF07974.13 KFP09153.1 - 0.27 11.6 27.9 13 6.3 9.9 3.8 2 1 0 2 2 2 0 EGF-like domain Aa_trans PF01490.18 KFP09154.1 - 5.3e-67 226.3 24.7 6.2e-67 226.1 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein E1_DerP2_DerF2 PF02221.15 KFP09155.1 - 1.9e-28 99.6 0.0 2.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF4928 PF16280.5 KFP09156.1 - 0.041 13.1 1.6 0.053 12.8 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4928) DUF1690 PF07956.11 KFP09156.1 - 0.052 14.0 10.3 0.026 14.9 7.9 1.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) FAM184 PF15665.5 KFP09156.1 - 0.18 11.5 13.1 0.37 10.5 13.0 1.5 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B CLZ PF16526.5 KFP09156.1 - 0.2 12.0 10.3 0.087 13.2 1.4 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FapA PF03961.13 KFP09156.1 - 0.21 10.2 5.3 0.22 10.1 5.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spectrin PF00435.21 KFP09156.1 - 0.24 11.9 11.3 0.43 11.1 10.7 1.9 1 1 0 1 1 1 0 Spectrin repeat Nuc_N PF14448.6 KFP09156.1 - 0.92 9.4 4.5 0.94 9.4 1.1 2.8 2 1 1 3 3 3 0 Nuclease N terminal FlxA PF14282.6 KFP09156.1 - 1.1 9.3 9.3 0.5 10.4 7.3 1.6 1 1 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.6 KFP09156.1 - 1.5 9.3 10.1 7.3 7.1 0.5 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) AA_permease_2 PF13520.6 KFP09157.1 - 2e-40 138.9 20.7 2e-40 138.9 20.7 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFP09157.1 - 1e-33 116.7 21.8 1e-33 116.7 21.8 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP09157.1 - 1.2e-18 66.9 8.1 1.2e-18 66.9 8.1 3.7 4 0 0 4 4 4 1 C-terminus of AA_permease Annexin PF00191.20 KFP09158.1 - 1.3e-188 611.4 33.4 4.5e-25 87.5 0.4 8.1 8 0 0 8 8 8 8 Annexin Sigma70_ner PF04546.13 KFP09158.1 - 0.0023 17.8 3.1 13 5.6 0.4 3.8 2 1 0 3 3 3 2 Sigma-70, non-essential region DUF5069 PF16798.5 KFP09158.1 - 0.0024 18.1 0.1 0.86 9.8 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF5069) GGDEF_2 PF17853.1 KFP09158.1 - 0.0032 17.7 0.1 0.04 14.2 0.1 2.8 2 1 0 2 2 2 1 GGDEF-like domain Myb_DNA-bind_7 PF15963.5 KFP09158.1 - 0.004 17.0 0.8 12 5.9 0.0 5.8 8 0 0 8 8 8 1 Myb DNA-binding like RuvC PF02075.17 KFP09158.1 - 0.021 14.7 0.1 21 5.0 0.0 3.5 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC HSCB_C PF07743.13 KFP09158.1 - 0.08 13.4 1.6 15 6.1 0.1 3.5 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF3574 PF12098.8 KFP09158.1 - 0.3 10.9 0.9 22 4.9 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) DUF2255 PF10012.9 KFP09158.1 - 0.78 9.9 3.2 76 3.5 0.1 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2255) GSHPx PF00255.19 KFP09159.1 - 7.3e-24 83.4 0.1 9.8e-24 83.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Dynactin_p62 PF05502.13 KFP09160.1 - 1.7e-30 106.2 17.4 5.5e-15 55.1 8.9 2.5 1 1 1 2 2 2 2 Dynactin p62 family Lgl_C PF08596.10 KFP09160.1 - 0.18 10.5 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Elf1 PF05129.13 KFP09160.1 - 6 7.0 9.6 19 5.4 6.9 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like RRM_1 PF00076.22 KFP09161.1 - 4.1e-11 42.5 0.1 6.6e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFP09161.1 - 2.8e-06 27.2 1.8 2.8e-06 27.2 1.8 2.1 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KFP09161.1 - 4.1e-06 27.5 0.2 1.4e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 KFP09161.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFP09161.1 - 0.00029 20.7 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP09161.1 - 0.0014 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif zf-CCCH PF00642.24 KFP09161.1 - 0.0019 18.0 1.8 0.0019 18.0 1.8 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFP09161.1 - 0.0056 16.4 1.8 0.013 15.3 1.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFP09161.1 - 0.0094 16.2 0.6 0.02 15.1 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger containing family FYVE PF01363.21 KFP09161.1 - 0.0099 16.0 0.6 0.0099 16.0 0.6 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.6 KFP09161.1 - 0.012 16.1 0.5 0.012 16.1 0.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zinc-ribbons_6 PF07191.12 KFP09161.1 - 1.9 8.5 9.2 4.5 7.3 9.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Calsarcin PF05556.11 KFP09162.1 - 5.4e-38 131.0 0.0 2.5e-37 128.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) HSNSD PF12062.8 KFP09163.1 - 1.3e-256 852.1 0.0 1.7e-256 851.7 0.0 1.1 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFP09163.1 - 2.5e-45 155.1 0.0 4e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP09163.1 - 5.6e-06 26.9 0.1 0.0046 17.4 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family Ribosomal_S11 PF00411.19 KFP09164.1 - 1.3e-39 135.0 2.1 2.5e-39 134.1 2.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFP09164.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) MHCassoc_trimer PF08831.10 KFP09165.1 - 1.2e-32 111.7 9.4 1.8e-32 111.2 9.4 1.3 1 0 0 1 1 1 1 Class II MHC-associated invariant chain trimerisation domain MHC2-interact PF09307.10 KFP09165.1 - 2.9e-29 101.2 1.9 5.9e-29 100.2 1.9 1.5 1 0 0 1 1 1 1 CLIP, MHC2 interacting TssO PF17561.2 KFP09165.1 - 0.075 13.1 0.2 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssO Treacle PF03546.14 KFP09167.1 - 5.1e-12 45.4 76.0 1.2e-07 31.0 53.0 6.8 1 1 5 6 6 6 5 Treacher Collins syndrome protein Treacle Sulfatase PF00884.23 KFP09168.1 - 1.4e-70 238.2 0.1 1.9e-70 237.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP09168.1 - 0.014 16.1 0.0 0.21 12.4 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Pkinase PF00069.25 KFP09169.1 - 2.4e-71 240.2 0.0 3.1e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 KFP09169.1 - 3.3e-64 214.8 0.0 5.1e-64 214.2 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 KFP09169.1 - 9.2e-30 103.8 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SnoaL_3 PF13474.6 KFP09169.1 - 1.3e-08 35.2 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFP09169.1 - 5.2e-08 33.3 0.0 8.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) APH PF01636.23 KFP09169.1 - 0.0037 17.2 0.4 1.3 8.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP09169.1 - 0.0048 15.7 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP09169.1 - 0.0099 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.7 KFP09169.1 - 0.051 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.6 KFP09169.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Pkinase_Tyr PF07714.17 KFP09171.1 - 3.2e-108 360.9 0.0 4.6e-108 360.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP09171.1 - 3e-44 151.4 0.0 5.5e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP09171.1 - 1.3e-28 99.4 8.2 4.1e-10 40.1 0.1 5.6 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFP09171.1 - 2.7e-27 94.6 4.5 1.7e-10 40.9 0.1 4.8 4 1 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 KFP09171.1 - 2.4e-22 78.9 4.4 3.3e-08 33.6 0.0 5.8 5 1 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFP09171.1 - 5.5e-19 68.3 8.9 1.5e-10 41.2 0.1 6.0 5 2 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFP09171.1 - 7.2e-06 26.1 10.8 0.0015 18.7 0.4 5.4 5 1 0 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP09171.1 - 7.4e-05 22.7 8.2 0.14 12.3 0.0 4.4 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP09171.1 - 0.00088 19.6 2.5 1.4 9.4 0.1 4.8 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 KFP09171.1 - 0.0026 17.5 2.2 7.7 6.4 0.0 3.8 4 0 0 4 4 3 1 Adenovirus E3 region protein CR1 Izumo-Ig PF16706.5 KFP09171.1 - 0.02 14.9 0.2 2 8.5 0.0 3.3 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP09171.1 - 0.021 14.4 0.0 0.47 10.1 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Pkinase_Tyr PF07714.17 KFP09172.1 - 3.9e-107 357.4 0.0 5.6e-107 356.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP09172.1 - 2.8e-43 148.2 0.0 1.7e-27 96.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP09172.1 - 1e-23 83.7 6.7 0.00012 22.6 0.3 5.7 4 1 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP09172.1 - 7.8e-19 67.7 5.9 0.00012 22.2 0.7 5.4 5 1 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 KFP09172.1 - 3.4e-18 65.5 0.0 0.0013 18.8 0.0 5.9 6 0 0 6 6 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP09172.1 - 1.1e-14 54.5 2.8 0.0001 22.6 0.1 4.7 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFP09172.1 - 9.7e-08 32.2 4.9 0.012 15.8 0.3 6.1 5 2 2 7 7 7 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP09172.1 - 4.6e-07 30.0 0.6 0.00033 20.9 0.0 3.3 3 0 0 3 3 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP09172.1 - 7.8e-05 23.0 0.1 0.0022 18.4 0.0 3.3 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 KFP09172.1 - 0.0079 16.4 0.1 9.6 6.5 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin C2-set domain APH PF01636.23 KFP09172.1 - 0.015 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Izumo-Ig PF16706.5 KFP09172.1 - 0.024 14.7 0.1 6.1 7.0 0.0 3.0 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Invasin_D3 PF09134.10 KFP09172.1 - 0.062 13.6 0.0 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 Invasin, domain 3 Haspin_kinase PF12330.8 KFP09172.1 - 0.13 11.1 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain HMG_box_2 PF09011.10 KFP09173.1 - 6.3e-12 45.9 0.4 1.4e-11 44.8 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KFP09173.1 - 3.4e-11 43.4 0.5 8.2e-11 42.2 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CxC4 PF18717.1 KFP09173.1 - 4e-11 42.9 0.2 1.3e-10 41.2 0.2 1.9 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases DUF1844 PF08899.11 KFP09173.1 - 0.19 12.0 0.1 0.61 10.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) zf-ribbon_3 PF13248.6 KFP09173.1 - 1.8 8.1 8.6 5.4 6.6 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-CCCH_2 PF14608.6 KFP09173.1 - 3.6 8.2 7.2 8.2 7.1 1.2 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger 7tm_1 PF00001.21 KFP09174.1 - 1.9e-53 181.5 20.5 2.3e-53 181.2 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP09174.1 - 2.9e-11 43.2 18.3 4.3e-11 42.7 18.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP09174.1 - 2.7e-07 30.6 15.0 4.4e-07 29.9 14.9 1.3 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP09174.1 - 0.00086 19.0 11.6 0.00086 19.0 11.6 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cyclin_N PF00134.23 KFP09174.1 - 0.06 13.1 0.9 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Pkinase_Tyr PF07714.17 KFP09175.1 - 1e-109 365.8 0.0 1.6e-109 365.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 KFP09175.1 - 2.5e-55 185.0 16.2 1.1e-11 45.2 0.0 7.2 6 1 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP09175.1 - 4.9e-44 148.3 8.9 3.1e-14 52.8 0.1 7.7 6 1 2 8 8 8 4 Immunoglobulin I-set domain Pkinase PF00069.25 KFP09175.1 - 4.8e-43 147.4 0.0 4.4e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_2 PF13895.6 KFP09175.1 - 1.1e-37 128.2 18.9 7.3e-10 39.0 0.1 9.2 8 2 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 KFP09175.1 - 2.4e-27 94.9 9.0 1.7e-07 31.3 0.1 6.8 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.17 KFP09175.1 - 1.3e-22 80.1 17.7 0.00021 21.4 0.2 8.6 6 3 2 8 8 8 6 Immunoglobulin V-set domain VEGFR-2_TMD PF17988.1 KFP09175.1 - 8e-20 70.0 3.7 1.5e-19 69.1 3.7 1.5 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain Izumo-Ig PF16706.5 KFP09175.1 - 4.5e-07 29.8 8.1 2.2 8.4 0.1 6.6 6 2 0 6 6 6 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFP09175.1 - 4.8e-07 30.1 8.9 0.56 10.6 0.0 7.0 6 1 1 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFP09175.1 - 5e-07 30.0 0.7 0.0021 18.4 0.1 4.9 5 0 0 5 5 4 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP09175.1 - 2e-05 24.0 1.8 13 5.5 0.0 6.1 7 0 0 7 7 7 0 Immunoglobulin domain Ig_4 PF16680.5 KFP09175.1 - 3.6e-05 23.9 9.0 4.4 7.6 0.1 6.1 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP09175.1 - 0.0001 22.3 4.5 1.2 9.3 0.0 4.8 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFP09175.1 - 0.00067 19.8 1.0 0.058 13.6 0.0 3.6 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 Herpes_gE PF02480.16 KFP09175.1 - 0.03 13.1 0.0 2 7.1 0.0 2.9 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Haspin_kinase PF12330.8 KFP09175.1 - 0.031 13.2 0.1 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain C2-set PF05790.15 KFP09175.1 - 0.44 10.7 1.9 2 8.6 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 KFP09175.1 - 4 7.3 6.8 5.1 7.0 0.1 3.7 4 1 0 4 4 4 0 Adenovirus E3 region protein CR1 UBA_5 PF16577.5 KFP09177.1 - 4.7e-41 138.8 0.1 8.4e-41 137.9 0.1 1.4 1 0 0 1 1 1 1 UBA domain ZZ PF00569.17 KFP09177.1 - 3.6e-13 49.1 2.8 6.5e-13 48.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 KFP09177.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KFP09177.1 - 0.012 15.9 2.4 0.028 14.7 2.4 1.6 1 0 0 1 1 1 0 C1 domain Glyco_transf_54 PF04666.13 KFP09178.1 - 3.1e-128 426.7 0.2 4.1e-128 426.3 0.2 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region STAR_dimer PF16544.5 KFP09178.1 - 0.33 10.5 2.9 0.18 11.4 0.3 2.0 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein MAPEG PF01124.18 KFP09179.1 - 0.0012 18.7 6.9 0.042 13.7 7.0 2.4 1 1 0 1 1 1 1 MAPEG family LHC PF00556.20 KFP09179.1 - 7 7.0 8.1 0.97 9.7 4.1 1.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF3432 PF11914.8 KFP09180.1 - 1.3e-36 124.7 38.8 1.3e-36 124.7 38.8 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3432) DUF3446 PF11928.8 KFP09180.1 - 3.9e-26 91.2 16.4 3.9e-26 91.2 16.4 4.0 3 1 1 4 4 3 1 Early growth response N-terminal domain zf-H2C2_2 PF13465.6 KFP09180.1 - 2.5e-16 59.2 17.8 9.5e-08 32.1 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP09180.1 - 2.8e-09 36.9 15.9 3.2e-05 24.1 0.3 4.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP09180.1 - 1.4e-07 31.7 11.0 0.0083 16.9 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP09180.1 - 0.0022 17.9 9.4 0.19 11.7 0.5 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFP09180.1 - 0.0045 17.1 1.7 0.28 11.3 0.1 2.3 1 1 1 2 2 2 1 KIAA1045 RING finger zf-C2H2_jaz PF12171.8 KFP09180.1 - 0.049 13.9 0.1 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP09180.1 - 0.065 13.5 3.2 0.56 10.5 0.9 2.9 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFP09180.1 - 0.17 11.7 0.1 0.17 11.7 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFP09180.1 - 1.4 8.7 6.1 24 4.8 0.1 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type TB2_DP1_HVA22 PF03134.19 KFP09181.1 - 5.4e-22 77.5 10.0 7.5e-22 77.1 10.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 2-Hacid_dh_C PF02826.19 KFP09182.1 - 8.8e-57 191.3 0.0 1.2e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP09182.1 - 4.5e-27 94.3 0.0 5.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP09182.1 - 8.4e-05 22.8 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KFP09182.1 - 0.084 13.4 0.0 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain GDNF PF02351.16 KFP09183.1 - 1.1e-40 138.4 43.3 2.6e-23 82.8 8.8 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain TPR_1 PF00515.28 KFP09184.1 - 2.6e-27 93.5 38.1 6.7e-06 25.7 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP09184.1 - 1.6e-25 87.1 38.1 0.00049 20.0 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat ANAPC8 PF04049.13 KFP09184.1 - 9.8e-24 84.0 7.9 2e-23 83.0 2.7 2.7 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KFP09184.1 - 1.4e-19 68.6 30.9 7.8e-05 22.6 0.0 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP09184.1 - 1.4e-14 53.5 19.1 0.0044 17.7 0.0 9.4 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP09184.1 - 5.7e-12 46.0 21.6 0.0013 19.2 0.1 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP09184.1 - 2.7e-09 37.5 14.2 0.0013 19.4 0.0 7.6 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP09184.1 - 9.5e-09 34.8 22.1 1.8e-06 27.6 0.2 5.9 5 1 1 6 6 6 3 TPR repeat TPR_7 PF13176.6 KFP09184.1 - 1.1e-08 34.5 22.2 0.095 12.8 0.3 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP09184.1 - 3.3e-07 30.4 37.0 0.00065 19.9 1.0 6.3 4 1 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP09184.1 - 5.7e-07 29.5 16.9 0.093 13.2 0.0 6.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP09184.1 - 7.6e-06 26.2 31.2 1.6 9.5 0.0 9.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP09184.1 - 1.4e-05 25.3 30.1 0.27 11.5 0.2 8.7 5 2 4 9 9 9 3 Tetratricopeptide repeat DUF772 PF05598.11 KFP09184.1 - 0.011 15.8 0.1 0.029 14.4 0.1 1.8 1 0 0 1 1 1 0 Transposase domain (DUF772) TPR_10 PF13374.6 KFP09184.1 - 0.014 15.2 15.2 11 6.1 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP09184.1 - 0.019 15.1 0.2 0.019 15.1 0.2 3.9 4 1 1 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 KFP09184.1 - 0.13 12.6 1.6 16 6.0 0.0 4.6 5 0 0 5 5 5 0 PPR repeat TPR_15 PF13429.6 KFP09184.1 - 0.16 11.1 9.5 0.1 11.8 1.7 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat JAKMIP_CC3 PF16034.5 KFP09186.1 - 4.4e-84 281.4 19.7 4.4e-84 281.4 19.7 6.6 3 2 1 6 6 6 1 JAKMIP CC3 domain Pox_A_type_inc PF04508.12 KFP09186.1 - 0.018 14.8 0.0 0.018 14.8 0.0 7.7 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat Amidohydro_1 PF01979.20 KFP09187.1 - 1.3e-37 130.0 0.0 1.6e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP09187.1 - 1.3e-12 48.0 0.3 2.5e-07 30.5 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFP09187.1 - 0.005 16.7 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase DUF3928 PF13065.6 KFP09187.1 - 0.079 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) GHMP_kinases_N PF00288.26 KFP09188.1 - 2.3e-20 72.6 0.4 6e-20 71.2 0.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFP09188.1 - 8.4e-07 29.3 1.6 2e-06 28.1 0.0 2.4 3 0 0 3 3 3 1 GHMP kinases C terminal Cob_adeno_trans PF01923.18 KFP09189.1 - 9.1e-38 130.0 0.0 9.9e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase T2SSF PF00482.23 KFP09189.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Hormone_3 PF00159.18 KFP09189.1 - 0.15 12.1 0.7 0.31 11.1 0.7 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide HECT PF00632.25 KFP09190.1 - 6.8e-94 314.8 0.0 1.7e-93 313.5 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFP09190.1 - 0.00093 18.8 3.2 0.0038 16.9 3.2 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif BTB_2 PF02214.22 KFP09191.1 - 9.9e-21 73.9 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP09191.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP09191.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Myosin_TH1 PF06017.13 KFP09192.1 - 3.2e-32 111.7 0.7 4.2e-32 111.3 0.7 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 KFP09192.1 - 0.067 13.6 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 Carmil pleckstrin homology domain ACC_central PF08326.12 KFP09193.1 - 1.1e-286 952.9 4.6 1.3e-286 952.6 4.6 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KFP09193.1 - 8.6e-178 592.0 0.0 1.1e-177 591.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFP09193.1 - 5e-52 176.5 0.1 1.1e-51 175.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFP09193.1 - 5.7e-23 81.1 0.0 1.7e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFP09193.1 - 7.8e-19 68.3 0.0 2.1e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFP09193.1 - 8.2e-13 48.0 0.0 2.3e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFP09193.1 - 4.5e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFP09193.1 - 0.00017 21.2 0.1 0.00037 20.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFP09193.1 - 0.00078 19.5 0.1 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFP09193.1 - 0.067 13.0 0.0 0.3 10.9 0.0 2.1 1 0 0 1 1 1 0 Biotin-lipoyl like Leuk-A4-hydro_C PF09127.11 KFP09193.1 - 0.12 12.5 1.3 4.2 7.5 0.1 3.0 3 0 0 3 3 3 0 Leukotriene A4 hydrolase, C-terminal UDG PF03167.19 KFP09194.1 - 4.9e-24 85.1 0.0 6.5e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 2OG-FeII_Oxy_2 PF13532.6 KFP09195.1 - 6.6e-27 95.0 0.0 8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UCH PF00443.29 KFP09196.1 - 2.9e-43 148.2 0.3 3.3e-43 148.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP09196.1 - 1.8e-17 63.9 5.5 4.1e-17 62.8 5.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 KFP09197.1 - 2e-32 112.7 29.8 6.3e-25 87.9 9.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFP09197.1 - 7.1e-32 110.7 44.7 3.8e-21 75.4 21.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP09197.1 - 0.0028 16.3 18.8 0.011 14.3 0.7 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein DAO PF01266.24 KFP09198.1 - 3.2e-30 105.9 0.0 3.7e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFP09198.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gp_dh_N PF00044.24 KFP09198.1 - 0.15 12.4 0.0 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DSPc PF00782.20 KFP09199.1 - 2.4e-34 118.0 0.1 5.9e-34 116.7 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 KFP09199.1 - 7.3e-15 54.6 2.6 2.1e-14 53.2 2.6 1.9 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 KFP09199.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF1899 PF08953.11 KFP09200.1 - 8.9e-32 108.8 0.0 1.7e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFP09200.1 - 5.1e-22 77.5 0.1 9.6e-22 76.6 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFP09200.1 - 2.5e-14 53.4 7.2 3.5e-05 24.5 0.6 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09200.1 - 2.1e-06 27.9 1.0 0.03 14.6 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP09200.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A FIN1 PF17300.2 KFP09200.1 - 0.013 15.1 2.0 0.018 14.5 2.0 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 RRM_1 PF00076.22 KFP09201.1 - 1.4e-32 111.3 0.1 3.6e-17 62.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM_int_assoc PF16605.5 KFP09201.1 - 1.7e-29 101.7 5.3 4.8e-29 100.2 5.3 1.9 1 0 0 1 1 1 1 LSM-interacting associated unstructured Lsm_interact PF05391.11 KFP09201.1 - 5.2e-07 28.9 2.0 1.3e-06 27.7 2.0 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_occluded PF16842.5 KFP09201.1 - 2.9e-05 23.8 0.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif FAT PF02259.23 KFP09201.1 - 0.0034 16.6 5.6 0.0088 15.3 5.6 1.7 1 0 0 1 1 1 1 FAT domain Nup35_RRM_2 PF14605.6 KFP09201.1 - 0.0055 16.7 0.1 2 8.5 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PPP4R2 PF09184.11 KFP09201.1 - 0.012 15.2 6.1 0.028 14.0 6.1 1.6 1 0 0 1 1 1 0 PPP4R2 TPR_14 PF13428.6 KFP09201.1 - 0.021 15.6 15.0 16 6.6 0.4 7.0 7 1 1 8 8 7 0 Tetratricopeptide repeat RRM_7 PF16367.5 KFP09201.1 - 0.057 13.5 0.1 2.9 8.1 0.0 3.1 2 1 0 2 2 2 0 RNA recognition motif DUF1866 PF08952.11 KFP09201.1 - 0.1 12.4 0.0 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) Hydin_ADK PF17213.3 KFP09201.1 - 1 9.6 5.4 2.3 8.5 5.4 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain V_ATPase_I PF01496.19 KFP09201.1 - 2 6.2 4.5 2.8 5.8 4.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 KFP09201.1 - 2.5 8.6 15.8 7.7 7.0 11.4 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RR_TM4-6 PF06459.12 KFP09201.1 - 2.5 7.8 10.6 7 6.4 10.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fic PF02661.18 KFP09202.1 - 1.1e-27 96.7 0.0 2.3e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family TPR_2 PF07719.17 KFP09202.1 - 0.0012 18.8 0.9 0.016 15.3 0.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP09202.1 - 0.045 14.4 0.1 0.1 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SLC3A2_N PF16028.5 KFP09202.1 - 0.17 11.4 1.3 0.34 10.5 1.3 1.4 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus TPR_11 PF13414.6 KFP09202.1 - 0.49 10.1 4.9 1 9.1 0.0 2.9 3 1 1 4 4 4 0 TPR repeat WSC PF01822.19 KFP09203.1 - 2.7e-29 101.2 13.6 9.7e-20 70.6 8.8 2.4 2 0 0 2 2 2 2 WSC domain Y_phosphatase PF00102.27 KFP09204.1 - 3.4e-78 262.4 0.5 4.3e-78 262.1 0.5 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP09204.1 - 7.7e-06 25.8 0.1 3.4e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP09204.1 - 0.00046 20.3 0.5 0.002 18.2 0.0 2.1 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFP09204.1 - 0.0005 20.1 0.1 0.0017 18.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family Tab2_like PF06485.11 KFP09204.1 - 0.074 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 SH2 PF00017.24 KFP09205.1 - 2.7e-25 88.3 0.0 3.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Ribosomal_L6e PF01159.19 KFP09206.1 - 2e-42 144.2 1.1 2e-42 144.2 1.1 2.9 2 1 1 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KFP09206.1 - 5.9e-27 93.7 14.3 5.9e-27 93.7 14.3 3.1 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain HECT PF00632.25 KFP09208.1 - 7.8e-42 143.8 0.0 1.6e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-TRAF PF02176.18 KFP09209.1 - 8.9e-06 26.3 3.6 8.9e-06 26.3 3.6 5.0 4 1 2 6 6 6 3 TRAF-type zinc finger XAF1_C PF18608.1 KFP09209.1 - 0.00024 20.6 15.5 0.069 12.7 0.4 5.1 4 2 2 6 6 6 3 XIAP-associated factor 1 C-terminal domain zf_C2HC_14 PF18574.1 KFP09209.1 - 0.0082 15.9 11.0 0.14 12.0 0.4 4.0 4 0 0 4 4 4 2 C2HC Zing finger domain zf_C2H2_6 PF18450.1 KFP09209.1 - 0.26 11.0 12.2 0.34 10.6 0.0 4.7 4 1 1 5 5 5 0 Zinc Finger domain PRP21_like_P PF12230.8 KFP09209.1 - 0.69 9.7 3.7 0.87 9.4 0.3 2.7 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein NatB_MDM20 PF09797.9 KFP09210.1 - 2.1e-125 418.7 1.5 2.1e-125 418.7 1.5 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KFP09210.1 - 0.00072 20.0 4.4 0.76 10.3 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP09210.1 - 0.0017 19.0 8.3 9.2 7.4 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 KFP09210.1 - 0.057 13.9 1.9 0.78 10.2 0.2 3.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 KFP09210.1 - 0.29 11.6 1.4 1.5e+02 3.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP09210.1 - 0.5 10.6 13.5 7.7 6.8 0.6 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP09210.1 - 0.81 10.0 6.8 12 6.3 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3510 PF12022.8 KFP09210.1 - 1.5 9.3 6.0 8.4 6.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) ERp29_N PF07912.13 KFP09211.1 - 9.8e-44 148.6 0.4 1.5e-43 148.0 0.4 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.12 KFP09211.1 - 3.9e-18 66.1 5.2 6.8e-18 65.4 5.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain PRTase_1 PF11202.8 KFP09211.1 - 0.014 14.7 1.5 0.022 14.0 1.5 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) GPR_Gpa2_C PF11970.8 KFP09212.1 - 0.00014 21.9 1.9 0.00033 20.6 1.9 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pkinase PF00069.25 KFP09213.1 - 1.5e-61 208.1 0.0 3.1e-61 207.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09213.1 - 1.2e-21 77.2 0.1 6.8e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFP09213.1 - 6.1e-05 22.5 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP09213.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KFP09213.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldedh PF00171.22 KFP09214.1 - 1.9e-185 616.8 0.0 2.1e-185 616.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DtxR PF18357.1 KFP09214.1 - 0.2 11.4 0.5 0.57 9.9 0.1 1.9 2 0 0 2 2 2 0 Diphteria toxin repressor SH3 domain Nrf1_DNA-bind PF10491.9 KFP09215.1 - 1.4e-116 387.6 0.1 2.1e-116 387.0 0.1 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.9 KFP09215.1 - 0.00088 19.9 6.7 0.00088 19.9 6.7 5.7 3 2 1 4 4 4 1 Nrf1 activator activation site binding domain DUF5008 PF16400.5 KFP09215.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) DUF3459 PF11941.8 KFP09215.1 - 0.094 13.1 0.6 0.37 11.2 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Peptidase_M23 PF01551.22 KFP09215.1 - 0.45 10.8 3.4 0.87 9.8 1.0 2.4 1 1 1 2 2 2 0 Peptidase family M23 DUF1639 PF07797.14 KFP09216.1 - 0.063 13.3 0.6 0.063 13.3 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1639) AdoHcyase PF05221.17 KFP09217.1 - 3.4e-33 115.1 0.2 2.3e-22 79.5 0.1 2.0 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase Frizzled PF01534.17 KFP09218.1 - 3.6e-82 276.0 15.5 2.9e-81 273.0 15.5 1.9 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 KFP09218.1 - 6.9e-05 22.1 1.9 6.9e-05 22.1 1.9 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Ras PF00071.22 KFP09219.1 - 2.2e-59 199.7 0.1 2.6e-59 199.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09219.1 - 2.2e-33 115.0 0.1 3.2e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09219.1 - 2.2e-10 40.3 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP09219.1 - 3e-07 30.5 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP09219.1 - 0.00013 22.3 0.0 0.00099 19.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFP09219.1 - 0.0014 18.5 0.1 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP09219.1 - 0.003 17.1 0.0 0.0091 15.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP09219.1 - 0.0073 16.7 0.1 0.011 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFP09219.1 - 0.012 15.7 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KFP09219.1 - 0.012 15.0 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KFP09219.1 - 0.044 14.3 0.1 0.085 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KFP09219.1 - 0.064 12.7 0.0 0.094 12.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP09219.1 - 0.087 12.2 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KFP09219.1 - 0.14 11.8 0.1 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain Robl_LC7 PF03259.17 KFP09220.1 - 1.4e-13 50.4 0.1 1.6e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain ubiquitin PF00240.23 KFP09221.1 - 1.3e-12 47.3 0.1 2.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFP09221.1 - 2.5e-08 33.7 60.1 0.00025 20.9 11.7 7.1 5 2 2 7 7 7 5 STI1 domain UBA PF00627.31 KFP09221.1 - 1.1e-06 28.4 0.9 1.1e-06 28.4 0.9 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFP09221.1 - 0.0017 18.1 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arm_2 PF04826.13 KFP09221.1 - 0.0068 15.9 0.3 0.0068 15.9 0.3 2.9 3 0 0 3 3 3 1 Armadillo-like Rad60-SLD_2 PF13881.6 KFP09221.1 - 0.014 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFP09221.1 - 0.017 15.5 0.2 0.045 14.1 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain HOIP-UBA PF16678.5 KFP09221.1 - 0.049 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair CUE PF02845.16 KFP09221.1 - 0.053 13.2 0.0 0.25 11.1 0.0 2.3 1 0 0 1 1 1 0 CUE domain ComX PF05952.12 KFP09221.1 - 1 9.4 9.1 35 4.4 0.2 5.1 4 1 1 5 5 5 0 Bacillus competence pheromone ComX 7tm_4 PF13853.6 KFP09222.1 - 2.7e-49 168.4 12.1 3.2e-49 168.2 12.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09222.1 - 4.1e-29 101.7 11.8 6.3e-29 101.1 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) fn3 PF00041.21 KFP09223.1 - 7.8e-264 853.0 75.8 2.4e-20 72.7 0.6 17.3 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.18 KFP09223.1 - 1.7e-148 482.5 166.6 9.7e-15 54.5 3.9 12.8 12 0 0 12 12 12 12 Fibronectin type I domain fn2 PF00040.19 KFP09223.1 - 2e-33 114.4 21.5 1.4e-16 60.4 7.2 3.7 2 0 0 2 2 2 2 Fibronectin type II domain Pur_ac_phosph_N PF16656.5 KFP09223.1 - 1.1e-31 109.2 53.8 0.0027 18.2 0.0 19.8 16 7 0 16 16 16 10 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFP09223.1 - 1.6e-27 95.7 12.5 0.19 12.1 0.0 13.8 13 1 1 14 14 14 7 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFP09223.1 - 1.4e-18 67.1 0.0 0.41 11.0 0.0 12.7 14 0 0 14 14 13 2 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFP09223.1 - 3.1e-12 46.7 4.5 0.75 10.1 0.0 8.7 9 0 0 9 9 9 2 Domain of unknown function (DUF4959) DUF4912 PF16258.5 KFP09223.1 - 9.4e-07 29.1 0.0 5.7 7.2 0.0 7.2 8 0 0 8 8 8 1 Domain of unknown function (DUF4912) TILa PF12714.7 KFP09223.1 - 0.0011 18.9 1.5 0.0011 18.9 1.5 11.3 5 3 7 12 12 12 1 TILa domain Glyco_hydro_66 PF13199.6 KFP09223.1 - 0.0019 17.0 3.6 19 3.7 0.0 5.9 3 2 2 6 6 6 0 Glycosyl hydrolase family 66 fn3_2 PF16893.5 KFP09223.1 - 0.0044 17.2 9.9 0.58 10.3 0.0 7.4 8 1 0 8 8 7 1 Fibronectin type III domain MG4 PF17789.1 KFP09223.1 - 0.011 15.8 0.2 0.095 12.9 0.2 2.7 1 0 0 1 1 1 0 Macroglobulin domain MG4 DUF1410 PF07198.11 KFP09223.1 - 0.047 14.2 7.6 86 3.7 0.0 7.1 8 0 0 8 8 8 0 Protein of unknown function (DUF1410) DUF2012 PF09430.10 KFP09223.1 - 0.072 13.2 0.1 30 4.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2012) Big_10 PF17964.1 KFP09223.1 - 3.4 7.6 7.4 9.9 6.1 0.1 4.5 4 0 0 4 4 4 0 Bacterial Ig domain AICARFT_IMPCHas PF01808.18 KFP09225.1 - 2.4e-95 319.4 0.3 3.2e-95 319.0 0.3 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFP09225.1 - 1.2e-24 86.3 0.0 2.4e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain PucR PF07905.11 KFP09225.1 - 0.097 12.9 0.0 6.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family ABC_tran PF00005.27 KFP09226.1 - 3.8e-54 182.9 0.4 8.6e-29 100.8 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 KFP09226.1 - 6e-48 163.7 51.8 2.1e-28 99.5 15.6 3.5 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFP09226.1 - 4e-26 92.6 1.0 7.6e-09 35.8 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFP09226.1 - 0.0039 17.9 0.0 0.017 15.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) IstB_IS21 PF01695.17 KFP09226.1 - 0.0063 16.3 0.9 0.69 9.6 0.0 3.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFP09226.1 - 0.018 15.6 0.5 0.018 15.6 0.5 4.2 4 1 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 KFP09226.1 - 0.039 13.8 0.9 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFP09226.1 - 0.041 14.3 0.0 5.5 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KFP09226.1 - 0.053 13.2 12.3 0.52 10.0 0.0 4.2 4 0 0 4 4 4 0 AAA ATPase domain AAA_29 PF13555.6 KFP09226.1 - 0.063 13.0 3.4 1.1 9.1 0.4 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KFP09226.1 - 0.094 12.4 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFP09226.1 - 0.11 12.6 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase CathepsinC_exc PF08773.11 KFP09226.1 - 0.14 12.4 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Cathepsin C exclusion domain SRP54 PF00448.22 KFP09226.1 - 0.22 11.1 3.7 1.8 8.1 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 KFP09226.1 - 3.9 6.7 31.7 0.11 11.8 14.1 2.9 3 0 0 3 3 3 0 ABC-2 family transporter protein Ank_5 PF13857.6 KFP09227.1 - 2.2e-18 66.1 2.5 2.1e-08 34.3 0.2 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP09227.1 - 2.9e-18 66.2 2.2 4.2e-15 56.1 1.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09227.1 - 3.6e-16 59.3 0.6 1.4e-08 35.1 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP09227.1 - 1.2e-14 54.0 3.8 2.2e-05 24.7 0.5 3.9 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_6 PF14835.6 KFP09227.1 - 3.3e-13 49.3 0.6 3.3e-13 49.3 0.6 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein Ank_3 PF13606.6 KFP09227.1 - 9.1e-13 47.2 0.1 0.0012 19.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat BRCT_2 PF16589.5 KFP09227.1 - 2.3e-10 40.7 0.1 9.4e-07 29.2 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFP09227.1 - 6.1e-09 36.1 0.1 5.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 KFP09227.1 - 0.0017 18.7 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein PTCB-BRCT PF12738.7 KFP09227.1 - 0.017 15.0 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain VWC PF00093.18 KFP09228.1 - 2.2e-07 31.0 39.3 2.9e-06 27.5 16.9 2.2 2 0 0 2 2 2 2 von Willebrand factor type C domain DUF4893 PF16233.5 KFP09231.1 - 0.044 13.4 0.1 0.13 11.9 0.0 1.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4893) bZIP_1 PF00170.21 KFP09231.1 - 0.16 12.0 0.5 0.16 12.0 0.5 2.9 3 0 0 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 KFP09231.1 - 1.2 9.3 12.1 4.1 7.5 1.2 3.7 3 3 1 4 4 4 0 Centrosome localisation domain of PPC89 YabA PF06156.13 KFP09231.1 - 7.5 7.3 10.7 1.7 9.3 2.0 2.9 2 1 1 3 3 3 0 Initiation control protein YabA zf-C2H2 PF00096.26 KFP09232.1 - 1.3e-15 56.8 43.1 8e-05 22.9 1.3 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP09232.1 - 2.4e-15 56.2 33.7 9.1e-08 32.2 2.7 7.2 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP09232.1 - 2.4e-11 43.5 41.4 0.00089 19.9 1.1 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP09232.1 - 4.7e-05 23.0 6.3 0.00041 20.0 1.3 5.2 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-MYND PF01753.18 KFP09232.1 - 0.0032 17.5 5.2 0.23 11.6 0.0 3.6 3 1 0 3 3 3 1 MYND finger GAGA PF09237.11 KFP09232.1 - 0.012 15.4 2.5 0.15 11.9 0.0 3.1 2 1 1 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.8 KFP09232.1 - 0.11 12.8 22.5 0.9 9.9 0.0 5.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP09232.1 - 0.29 11.6 0.2 0.29 11.6 0.2 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP09232.1 - 0.38 11.1 13.5 0.079 13.3 2.6 3.5 3 1 0 3 3 3 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 KFP09232.1 - 0.4 11.2 24.8 0.99 9.9 1.2 5.9 5 1 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 KFP09232.1 - 1.5 9.2 8.3 2 8.7 0.3 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-C2H2_11 PF16622.5 KFP09232.1 - 6.5 6.6 18.7 0.12 12.2 0.3 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-TRAF PF02176.18 KFP09232.1 - 6.6 7.5 16.2 0.72 10.6 4.2 3.5 3 0 0 3 3 3 0 TRAF-type zinc finger Pkinase_Tyr PF07714.17 KFP09235.1 - 1.9e-90 302.7 0.0 3.4e-90 301.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFP09235.1 - 1.6e-58 195.7 4.0 1.1e-29 102.8 0.2 2.4 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.6 KFP09235.1 - 6.8e-53 178.0 82.0 6.8e-47 158.6 28.7 3.9 2 1 1 3 3 3 3 Growth factor receptor domain IV Pkinase PF00069.25 KFP09235.1 - 3.6e-39 134.7 0.0 5.7e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFP09235.1 - 3.8e-36 124.2 87.8 1e-28 100.1 42.3 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region Haspin_kinase PF12330.8 KFP09235.1 - 0.003 16.6 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP09235.1 - 0.003 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP09235.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3951 PF13131.6 KFP09235.1 - 0.08 13.1 1.6 0.18 12.0 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Adeno_E3_CR2 PF02439.15 KFP09235.1 - 0.27 11.0 2.1 0.67 9.8 2.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RVT_1 PF00078.27 KFP09240.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LANC_like PF05147.13 KFP09242.1 - 6.9e-107 357.1 0.1 8.7e-107 356.7 0.1 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 KFP09242.1 - 0.01 14.3 1.6 1.3 7.4 0.3 2.5 2 2 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 KFP09242.1 - 0.16 11.5 3.5 0.94 8.9 0.0 3.2 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus EF-hand_1 PF00036.32 KFP09244.1 - 1.2e-11 43.3 3.5 0.011 15.2 0.1 5.0 4 2 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFP09244.1 - 1.5e-11 43.2 0.7 0.00023 20.8 0.2 4.3 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFP09244.1 - 3.4e-11 43.4 0.2 6.9e-05 23.2 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP09244.1 - 1.3e-06 28.1 1.9 0.044 13.6 0.1 3.3 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 KFP09244.1 - 0.00038 20.7 0.0 0.53 10.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Cas9_REC PF16592.5 KFP09244.1 - 0.013 14.2 0.2 0.015 14.1 0.2 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 DUF2267 PF10025.9 KFP09244.1 - 0.093 13.0 0.2 0.59 10.4 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Acyl-CoA_dh_1 PF00441.24 KFP09245.1 - 4e-42 144.0 0.1 5.5e-42 143.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP09245.1 - 1.4e-30 106.2 0.0 3.1e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP09245.1 - 1.4e-25 89.3 0.0 4.4e-25 87.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP09245.1 - 3.2e-08 33.9 0.0 4.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFP09245.1 - 0.017 15.7 0.1 0.038 14.5 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal PEHE PF15275.6 KFP09246.1 - 3.1e-21 76.3 8.1 3.1e-21 76.3 8.1 4.5 4 0 0 4 4 4 1 PEHE domain DUF3562 PF12085.8 KFP09246.1 - 0.14 11.8 0.2 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) Ribul_P_3_epim PF00834.19 KFP09247.1 - 9.4e-45 152.4 0.1 1.2e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KFP09247.1 - 0.0036 17.1 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KFP09247.1 - 0.0057 16.3 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 KFP09247.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 KFP09247.1 - 0.075 12.5 0.0 0.28 10.6 0.0 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein UNC80 PF15778.5 KFP09248.1 - 6.1e-90 299.9 0.0 7.9e-90 299.5 0.0 1.1 1 0 0 1 1 1 1 Cation channel complex component UNC80 Tubulin-binding PF00418.19 KFP09249.1 - 6.7e-63 208.3 21.1 9.8e-16 57.5 2.6 5.5 5 0 0 5 5 5 5 Tau and MAP protein, tubulin-binding repeat RII_binding_1 PF10522.9 KFP09249.1 - 0.00042 20.2 2.9 0.0011 18.9 2.9 1.7 1 0 0 1 1 1 1 RII binding domain NTR PF01759.21 KFP09251.1 - 3e-22 78.4 3.7 3.8e-22 78.1 0.9 1.9 1 1 1 2 2 2 2 UNC-6/NTR/C345C module Nckap1 PF09735.9 KFP09252.1 - 0 1676.9 28.4 0 1676.7 28.4 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DSPc PF00782.20 KFP09253.1 - 2.4e-31 108.3 0.0 2.7e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP09253.1 - 0.0014 18.2 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nup35_RRM PF05172.13 KFP09254.1 - 3.4e-27 94.4 0.1 5.5e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KFP09254.1 - 8.8e-11 41.6 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif HPHLAWLY PF14925.6 KFP09254.1 - 0.023 13.4 2.1 0.032 12.9 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function zf-C2H2_jaz PF12171.8 KFP09256.1 - 8e-06 26.0 9.2 8e-06 26.0 9.2 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP09256.1 - 0.00087 19.6 2.2 0.005 17.2 2.2 2.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Lectin_C PF00059.21 KFP09258.1 - 1.6e-11 44.8 6.2 2e-11 44.6 6.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.21 KFP09259.1 - 6.7e-14 52.5 0.9 1e-13 51.9 0.9 1.3 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFP09259.1 - 0.00095 18.9 0.2 0.0017 18.0 0.2 1.4 1 1 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like Toxin_13 PF07822.11 KFP09259.1 - 0.074 13.2 0.9 0.25 11.5 0.9 1.9 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein PRY PF13765.6 KFP09260.1 - 2.7e-15 55.7 0.0 4.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.28 KFP09260.1 - 1.8e-12 47.5 0.1 2.2e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 SPRY domain GNT-I PF03071.15 KFP09261.1 - 2.3e-144 481.4 0.1 2.6e-144 481.2 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KFP09261.1 - 0.0021 18.0 0.2 0.02 14.8 0.2 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Med26 PF08711.11 KFP09262.1 - 0.003 17.5 0.9 0.0075 16.3 0.9 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TraQ PF09679.10 KFP09262.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) NST1 PF13945.6 KFP09262.1 - 0.24 11.5 14.0 4.8 7.2 10.0 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Presenilin PF01080.17 KFP09262.1 - 9.2 4.9 6.0 15 4.2 6.0 1.3 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 KFP09265.1 - 2.1e-28 98.0 10.9 6.4e-06 26.8 0.0 6.3 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09265.1 - 8.3e-09 35.6 0.2 0.12 12.7 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP09265.1 - 1.2e-05 25.2 0.0 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP09265.1 - 0.003 16.6 0.1 0.032 13.2 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFP09265.1 - 0.058 13.4 0.1 72 3.5 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cornichon PF03311.14 KFP09266.1 - 2e-42 144.4 2.5 2.3e-42 144.2 2.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2650 PF10853.8 KFP09266.1 - 0.47 10.2 3.6 2.5 7.9 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2650) AAA PF00004.29 KFP09267.1 - 1.6e-92 306.9 0.0 1.4e-47 161.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP09267.1 - 4.5e-26 90.4 0.3 6.7e-12 45.0 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain Nucleolin_bd PF16725.5 KFP09267.1 - 1.4e-21 75.9 0.1 2.8e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Nucleolin binding domain RuvB_N PF05496.12 KFP09267.1 - 1.3e-13 51.0 0.0 1e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFP09267.1 - 2.8e-12 47.3 4.9 0.011 16.1 0.0 5.5 3 2 2 5 5 5 2 AAA ATPase domain AAA_2 PF07724.14 KFP09267.1 - 4.8e-12 46.3 0.0 5e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP09267.1 - 1.6e-10 41.4 5.5 0.079 13.2 0.0 4.9 4 2 2 6 6 4 3 AAA domain AAA_5 PF07728.14 KFP09267.1 - 3.5e-10 40.0 1.6 0.00011 22.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFP09267.1 - 1.6e-08 34.6 0.0 0.0074 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KFP09267.1 - 1.7e-08 34.1 0.1 0.0043 16.3 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KFP09267.1 - 4.4e-08 33.4 0.0 0.0044 17.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 KFP09267.1 - 8.8e-08 31.8 0.2 0.0063 15.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFP09267.1 - 5e-07 30.1 0.0 0.054 13.9 0.0 3.0 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFP09267.1 - 1.2e-06 28.8 0.0 0.054 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFP09267.1 - 1.9e-06 27.8 0.0 0.085 12.6 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KFP09267.1 - 2.3e-06 28.2 0.0 0.02 15.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFP09267.1 - 2.4e-06 27.0 0.3 0.0035 16.6 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin Viral_helicase1 PF01443.18 KFP09267.1 - 2.5e-06 27.4 0.0 0.065 13.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KFP09267.1 - 6.2e-06 26.2 0.0 0.057 13.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFP09267.1 - 6.3e-06 26.2 0.7 0.045 13.7 0.0 3.0 2 1 0 2 2 2 2 NACHT domain Vps4_C PF09336.10 KFP09267.1 - 1.5e-05 24.8 0.6 0.17 11.9 0.1 3.0 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 KFP09267.1 - 1.6e-05 24.8 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFP09267.1 - 2.6e-05 24.3 0.1 0.11 12.4 0.0 2.9 2 1 1 3 3 3 2 Rad17 P-loop domain ATPase PF06745.13 KFP09267.1 - 3.4e-05 23.3 1.7 0.68 9.2 0.0 4.1 3 1 0 4 4 3 1 KaiC AAA_17 PF13207.6 KFP09267.1 - 3.6e-05 24.2 0.0 0.57 10.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KFP09267.1 - 7.2e-05 23.3 2.4 0.26 11.8 0.0 3.6 5 1 0 5 5 2 2 ABC transporter Cytidylate_kin2 PF13189.6 KFP09267.1 - 9.5e-05 22.6 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.22 KFP09267.1 - 0.00029 20.1 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activat PF00158.26 KFP09267.1 - 0.00029 20.6 0.0 0.41 10.3 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KFP09267.1 - 0.00039 20.5 0.0 0.96 9.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.9 KFP09267.1 - 0.00085 18.7 0.0 1.4 8.0 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KFP09267.1 - 0.001 18.7 4.5 1.7 8.2 0.2 3.6 2 2 2 4 4 4 2 AAA domain AAA_7 PF12775.7 KFP09267.1 - 0.0017 17.9 0.0 2.8 7.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_11 PF13086.6 KFP09267.1 - 0.0023 17.8 2.0 1.6 8.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 KFP09267.1 - 0.003 17.0 0.1 1.5 8.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 KFP09267.1 - 0.0042 16.3 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFP09267.1 - 0.0062 16.3 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.17 KFP09267.1 - 0.0068 15.5 0.0 2.6 7.1 0.0 2.6 2 1 0 2 2 2 1 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 KFP09267.1 - 0.011 15.6 0.0 6.3 6.7 0.0 3.1 2 1 1 3 3 3 0 NTPase AAA_24 PF13479.6 KFP09267.1 - 0.013 15.2 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KFP09267.1 - 0.016 15.3 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 KFP09267.1 - 0.017 15.0 0.0 11 5.8 0.0 3.4 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFP09267.1 - 0.024 15.0 1.0 6.5 7.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFP09267.1 - 0.045 13.5 0.0 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KFP09267.1 - 0.13 11.4 0.1 5.9 6.0 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 FA_desaturase PF00487.24 KFP09268.1 - 4.6e-25 88.9 14.1 4.6e-25 88.9 14.1 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 KFP09268.1 - 0.0021 17.5 0.2 0.0043 16.5 0.2 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ATG16 PF08614.11 KFP09269.1 - 2.7e-05 24.5 3.1 2.7e-05 24.5 3.1 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) FAM76 PF16046.5 KFP09269.1 - 0.00011 21.7 1.4 0.0002 20.8 1.4 1.6 1 0 0 1 1 1 1 FAM76 protein DUF3287 PF11690.8 KFP09269.1 - 0.0029 17.3 1.4 0.011 15.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3287) SlyX PF04102.12 KFP09269.1 - 0.0038 17.8 8.5 0.0038 17.8 8.5 2.7 2 1 1 3 3 3 1 SlyX Filament PF00038.21 KFP09269.1 - 0.0074 15.9 8.2 0.015 14.9 8.2 1.4 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 KFP09269.1 - 0.0085 15.0 8.6 0.016 14.1 8.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein FmiP_Thoc5 PF09766.9 KFP09269.1 - 0.021 14.1 6.7 0.033 13.5 6.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TMF_DNA_bd PF12329.8 KFP09269.1 - 0.071 13.1 11.4 0.61 10.1 7.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 KFP09269.1 - 0.13 11.6 9.1 0.3 10.4 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KFP09269.1 - 0.16 12.5 8.0 0.047 14.2 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 SKA1 PF07160.12 KFP09269.1 - 0.19 11.6 8.4 0.4 10.5 8.4 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF2730 PF10805.8 KFP09269.1 - 0.2 11.7 3.3 1.6 8.9 3.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 KFP09269.1 - 0.32 10.3 3.6 0.6 9.4 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HemX PF04375.14 KFP09269.1 - 0.36 10.1 9.9 0.75 9.0 9.9 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase YabA PF06156.13 KFP09269.1 - 1.1 9.9 7.7 4.8 7.9 5.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA COG2 PF06148.11 KFP09269.1 - 1.4 9.0 6.7 3.9 7.6 3.8 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran_CTD PF16326.5 KFP09269.1 - 1.6 9.1 11.0 6.4 7.1 10.9 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 KFP09269.1 - 2 8.8 4.8 1.5 9.3 1.9 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 KFP09269.1 - 2.4 8.5 15.2 2.1 8.7 13.4 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) KASH_CCD PF14662.6 KFP09269.1 - 3.2 7.5 16.7 1.5 8.6 3.2 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 KFP09269.1 - 3.6 8.1 10.2 1.6 9.2 3.7 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 KFP09269.1 - 4.9 7.4 14.5 3.8 7.8 11.3 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ank_2 PF12796.7 KFP09270.1 - 4.7e-17 62.4 0.0 1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09270.1 - 7.6e-17 61.5 0.0 2.1e-11 44.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP09270.1 - 5.4e-14 51.9 0.0 5.1e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP09270.1 - 1.1e-13 50.0 0.0 4e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat SH3_1 PF00018.28 KFP09270.1 - 9.2e-12 44.4 1.7 1.8e-11 43.5 1.7 1.4 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.6 KFP09270.1 - 7.7e-10 38.8 0.6 4.8e-08 33.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_9 PF14604.6 KFP09270.1 - 8e-10 38.4 0.4 1.7e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP09270.1 - 2.1e-07 30.5 0.0 4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 KFP09270.1 - 0.0086 16.7 0.7 0.26 11.9 0.7 2.7 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cwf21 PF08312.12 KFP09270.1 - 1.7 8.9 6.2 1.9 8.7 3.5 2.6 2 0 0 2 2 2 0 cwf21 domain Peptidase_C2 PF00648.21 KFP09271.1 - 8.9e-130 432.0 0.1 1.7e-129 431.1 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP09271.1 - 5.7e-50 169.2 0.0 2.9e-49 166.9 0.0 2.0 2 0 0 2 2 2 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFP09271.1 - 1e-12 46.6 0.1 0.00038 19.8 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP09271.1 - 6.5e-12 44.4 0.1 0.0089 15.9 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP09271.1 - 6.2e-07 29.2 1.4 2.7e-05 23.9 0.1 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP09271.1 - 8.5e-05 22.9 1.3 0.29 11.6 0.2 4.1 2 2 0 2 2 2 1 EF-hand domain pair Ndufs5 PF10200.9 KFP09271.1 - 0.012 15.9 0.0 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa EF-hand_5 PF13202.6 KFP09271.1 - 0.016 14.6 0.0 20 4.9 0.0 3.7 4 0 0 4 4 4 0 EF hand Alpha_adaptin_C PF02296.16 KFP09271.1 - 0.11 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Sushi PF00084.20 KFP09272.1 - 2e-33 114.8 23.0 2.3e-08 34.5 0.3 4.3 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) cEGF PF12662.7 KFP09272.1 - 0.0021 17.9 14.9 5.3 7.1 0.1 5.5 5 0 0 5 5 5 4 Complement Clr-like EGF-like HRM PF02793.22 KFP09272.1 - 0.4 11.0 7.5 1.8 8.9 0.4 3.9 3 1 0 3 3 3 0 Hormone receptor domain Patched PF02460.18 KFP09274.1 - 1.8e-21 76.0 27.4 2.8e-14 52.2 8.0 2.6 2 0 0 2 2 2 2 Patched family MMPL PF03176.15 KFP09274.1 - 3.3e-14 52.6 21.9 1.2e-08 34.3 7.4 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KFP09274.1 - 4.5e-11 42.8 13.2 4.5e-11 42.8 13.2 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation BRO1 PF03097.18 KFP09275.1 - 6.1e-40 137.2 0.3 8.3e-40 136.8 0.3 1.1 1 0 0 1 1 1 1 BRO1-like domain Aida_C2 PF14186.6 KFP09276.1 - 4.2e-65 217.8 0.3 5.3e-65 217.5 0.3 1.1 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 KFP09276.1 - 2.1e-16 60.2 0.2 4e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 Aida N-terminus NPIP PF06409.11 KFP09277.1 - 1.1e-15 57.4 7.7 2.4e-07 30.1 9.9 2.6 2 0 0 2 2 2 2 Nuclear pore complex interacting protein (NPIP) SH3_2 PF07653.17 KFP09277.1 - 1.1e-07 31.4 0.0 2.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF508 PF04370.12 KFP09277.1 - 0.095 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) ANAPC5 PF12862.7 KFP09277.1 - 0.23 11.6 2.5 13 6.0 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 DUF501 PF04417.12 KFP09277.1 - 0.52 10.1 27.8 0.032 14.1 1.3 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF501) TAF1_subA PF14929.6 KFP09279.1 - 2.6e-127 425.3 15.3 3e-127 425.1 15.3 1.0 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_8 PF13181.6 KFP09279.1 - 6.2 7.3 6.1 12 6.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat GSDH PF07995.11 KFP09280.1 - 3.3e-38 131.8 0.0 5.8e-38 131.0 0.0 1.3 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFP09280.1 - 1.8e-09 37.7 11.9 3.3e-09 36.9 11.9 1.4 1 0 0 1 1 1 1 Folate receptor family DSPc PF00782.20 KFP09281.1 - 5e-42 142.9 0.7 1.1e-41 141.8 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFP09281.1 - 9.9e-15 55.0 0.0 3e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 KFP09281.1 - 7.2e-06 26.2 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP09281.1 - 8.7e-05 22.2 0.1 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP09281.1 - 0.0021 18.4 0.6 0.017 15.4 0.0 2.6 3 0 0 3 3 3 1 Rit1 DUSP-like domain AAA_18 PF13238.6 KFP09281.1 - 0.11 13.1 0.0 6 7.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain MOSC PF03473.17 KFP09282.1 - 1.4e-34 119.0 0.0 1.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFP09282.1 - 1.5e-22 79.7 0.0 2.9e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Lenti_VIF_2 PF07401.12 KFP09282.1 - 0.057 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein Pkinase PF00069.25 KFP09283.1 - 7e-76 255.1 0.0 1e-75 254.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09283.1 - 5.6e-44 150.4 0.0 8.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFP09283.1 - 9.4e-21 73.3 0.0 1.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFP09283.1 - 4.3e-07 29.6 0.0 9.8e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like UBA PF00627.31 KFP09283.1 - 8.6e-07 28.7 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 KFP09283.1 - 0.00056 19.6 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.11 KFP09283.1 - 0.0034 17.5 0.1 0.0089 16.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kdo PF06293.14 KFP09283.1 - 0.0074 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP09283.1 - 0.071 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP09283.1 - 0.074 13.0 0.1 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Steroid_dh PF02544.16 KFP09285.1 - 7.7e-60 201.2 4.0 9.2e-60 201.0 4.0 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFP09285.1 - 2.5e-06 27.2 0.1 3.1e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KFP09285.1 - 0.011 16.2 1.5 0.032 14.6 1.5 1.8 1 1 0 1 1 1 0 Phospholipid methyltransferase Memo PF01875.17 KFP09286.1 - 9.3e-75 251.3 0.0 1.1e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Glycolytic PF00274.19 KFP09286.1 - 0.068 11.9 0.1 0.098 11.4 0.1 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Dpy-30 PF05186.13 KFP09287.1 - 3.3e-09 36.3 0.9 3.9e-09 36.1 0.1 1.6 2 0 0 2 2 2 1 Dpy-30 motif AAA PF00004.29 KFP09288.1 - 9.5e-40 136.1 0.0 2.9e-39 134.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP09288.1 - 7e-09 35.4 0.4 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KFP09288.1 - 4.2e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KFP09288.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KFP09288.1 - 4.5e-05 23.7 0.4 0.02 15.1 0.1 3.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP09288.1 - 0.00014 21.8 0.2 0.0024 17.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP09288.1 - 0.00031 20.0 0.1 0.00096 18.5 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain TniB PF05621.11 KFP09288.1 - 0.00058 19.3 1.4 0.4 10.1 0.0 3.4 3 1 1 4 4 4 2 Bacterial TniB protein AAA_2 PF07724.14 KFP09288.1 - 0.0012 19.0 0.0 0.0043 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KFP09288.1 - 0.0024 17.3 0.5 0.0081 15.6 0.5 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFP09288.1 - 0.0071 16.4 0.0 0.045 13.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KFP09288.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFP09288.1 - 0.0083 16.5 1.9 0.1 12.9 0.3 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 KFP09288.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFP09288.1 - 0.017 14.3 0.1 0.036 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KFP09288.1 - 0.033 14.0 0.0 0.085 12.7 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein MIT PF04212.18 KFP09288.1 - 0.05 13.7 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_18 PF13238.6 KFP09288.1 - 0.07 13.7 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KFP09288.1 - 0.083 13.1 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFP09288.1 - 0.13 11.9 0.1 0.93 9.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Cation_efflux PF01545.21 KFP09290.1 - 3.7e-32 111.7 14.8 6e-32 111.0 14.8 1.3 1 0 0 1 1 1 1 Cation efflux family Peptidase_M28 PF04389.17 KFP09291.1 - 4.2e-48 163.7 0.0 5.3e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 KFP09292.1 - 1.5e-70 237.6 0.0 2.5e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09292.1 - 6.6e-33 114.1 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP09292.1 - 3.8e-28 97.1 19.2 2.9e-14 52.7 3.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP09292.1 - 1.5e-09 38.3 0.6 2.8e-07 31.0 0.1 3.2 2 1 1 3 3 3 1 PH domain Kinase-like PF14531.6 KFP09292.1 - 1.6e-07 30.9 0.0 3.4e-06 26.6 0.0 2.6 2 1 0 3 3 3 1 Kinase-like C1_2 PF03107.16 KFP09292.1 - 1.3e-05 25.4 15.0 0.0095 16.2 1.6 2.6 2 0 0 2 2 2 2 C1 domain Kdo PF06293.14 KFP09292.1 - 1.6e-05 24.4 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_9 PF13901.6 KFP09292.1 - 0.061 13.3 12.8 1.1 9.2 0.4 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon RIO1 PF01163.22 KFP09292.1 - 0.13 11.9 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFP09292.1 - 0.13 12.2 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFP09292.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FYVE_2 PF02318.16 KFP09292.1 - 0.79 9.9 11.0 3.4 7.9 5.7 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 KFP09292.1 - 1.2 9.0 19.8 1.5 8.7 3.2 2.6 2 0 0 2 2 2 0 PHD-finger CBF PF03914.17 KFP09293.1 - 1.4e-55 187.9 0.3 1.4e-55 187.9 0.3 3.3 3 0 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 KFP09293.1 - 0.034 14.2 2.5 0.035 14.2 0.7 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Sulfotransfer_1 PF00685.27 KFP09294.1 - 7.6e-38 130.5 0.1 8.9e-38 130.3 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP09294.1 - 7.3e-05 23.2 0.0 0.0001 22.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF1266 PF06889.11 KFP09294.1 - 0.2 11.7 2.4 0.26 11.3 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) GON PF08685.11 KFP09297.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 GON domain VWC PF00093.18 KFP09302.1 - 1.7e-38 130.7 127.3 4.2e-11 43.0 14.5 16.2 10 2 6 16 16 16 6 von Willebrand factor type C domain Antistasin PF02822.14 KFP09302.1 - 3.1e-16 59.7 62.6 6.1e-07 30.0 11.0 15.6 16 2 1 17 17 17 4 Antistasin family IGFBP PF00219.18 KFP09302.1 - 4.6e-07 30.4 15.8 4.6e-07 30.4 15.8 16.7 9 5 7 17 17 17 1 Insulin-like growth factor binding protein Amnionless PF14828.6 KFP09302.1 - 0.00083 18.3 11.5 0.00083 18.3 11.5 9.2 10 1 0 10 10 10 6 Amnionless TILa PF12714.7 KFP09302.1 - 0.0015 18.4 26.8 0.0019 18.1 5.9 13.2 12 3 2 14 14 14 6 TILa domain FEZ PF07763.13 KFP09303.1 - 2.7e-88 295.8 14.8 3.4e-88 295.5 14.8 1.1 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.9 KFP09303.1 - 0.002 17.8 0.4 0.0035 17.0 0.4 1.5 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 Gluconate_2-dh3 PF13618.6 KFP09303.1 - 0.054 13.7 0.2 0.11 12.8 0.2 1.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF5102 PF17104.5 KFP09303.1 - 0.11 12.5 9.2 0.34 10.9 7.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5102) EURL PF06937.11 KFP09303.1 - 0.48 9.8 8.7 0.15 11.4 5.8 1.6 1 1 1 2 2 2 0 EURL protein CdiI_2 PF18593.1 KFP09303.1 - 0.83 10.3 6.4 7.3 7.3 0.3 3.0 1 1 0 2 2 2 0 CdiI immunity protein Ribosomal_L12_N PF16320.5 KFP09303.1 - 1.2 8.9 6.4 1 9.1 1.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain V_ATPase_I PF01496.19 KFP09303.1 - 1.5 6.6 6.8 1.8 6.4 6.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KFP09303.1 - 2.7 8.5 8.7 11 6.5 0.8 3.5 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein 7tm_4 PF13853.6 KFP09304.1 - 3e-42 145.3 10.6 3.7e-42 145.0 10.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09304.1 - 1.4e-28 99.9 10.1 2.1e-28 99.4 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP09304.1 - 0.00092 18.7 10.9 0.0013 18.1 10.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP09305.1 - 1e-39 137.0 16.3 1.2e-39 136.8 16.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09305.1 - 3e-25 89.0 13.7 5.9e-25 88.1 13.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP09305.1 - 0.085 12.9 0.0 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Cholecystokinin A receptor, N-terminal Ribosomal_L38e PF01781.18 KFP09306.1 - 3.2e-21 75.2 1.3 3.3e-21 75.1 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family RE_MamI PF09567.10 KFP09306.1 - 0.04 13.6 0.2 0.042 13.5 0.2 1.0 1 0 0 1 1 1 0 MamI restriction endonuclease Tweety PF04906.13 KFP09307.1 - 6.8e-117 390.6 7.7 8.3e-117 390.3 7.7 1.0 1 0 0 1 1 1 1 Tweety Tetraspanin PF00335.20 KFP09307.1 - 1.1 8.9 14.2 0.26 11.0 10.8 1.8 1 1 0 1 1 1 0 Tetraspanin family WD40 PF00400.32 KFP09308.1 - 0.0063 17.3 8.2 0.047 14.6 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat HlyE PF06109.13 KFP09308.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) TAL_effector PF03377.13 KFP09310.1 - 0.0015 18.8 0.4 0.002 18.4 0.4 1.2 1 0 0 1 1 1 1 TAL effector repeat Oxidored-like PF09791.9 KFP09310.1 - 0.023 14.4 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal NPL4 PF05021.15 KFP09311.1 - 8.1e-95 317.7 0.1 5.9e-94 314.9 0.1 2.1 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KFP09311.1 - 2.6e-62 209.3 0.2 4.3e-62 208.5 0.2 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFP09311.1 - 5.4e-31 106.9 0.0 1e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-Di19 PF05605.12 KFP09313.1 - 0.018 15.3 1.5 0.31 11.4 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 KFP09313.1 - 0.037 13.5 1.6 2.5 7.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KFP09313.1 - 0.037 14.0 1.6 0.19 11.8 1.6 2.0 1 1 0 1 1 1 0 Double zinc ribbon Cys_rich_CPXG PF14255.6 KFP09313.1 - 0.06 13.3 0.9 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-UDP PF14569.6 KFP09313.1 - 0.19 11.9 3.0 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 KFP09313.1 - 0.43 10.9 7.9 1.6 9.1 7.9 2.0 1 1 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KFP09313.1 - 1 9.7 7.7 3 8.2 7.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 KFP09313.1 - 1.6 9.0 7.9 3.5 7.9 4.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Mg_trans_NIPA PF05653.14 KFP09314.1 - 1.5e-147 490.4 17.2 1.8e-147 490.2 17.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP09314.1 - 3.2e-09 37.1 4.0 3.2e-09 37.1 4.0 4.2 3 1 0 3 3 3 2 EamA-like transporter family DUF2627 PF11118.8 KFP09314.1 - 0.62 10.7 5.2 6.2 7.5 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) FragX_IP PF05994.11 KFP09315.1 - 0 1328.9 6.4 0 1328.9 6.4 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KFP09315.1 - 5.6e-08 32.4 6.2 1.4e-07 31.1 6.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) zf-CW PF07496.15 KFP09315.1 - 0.098 12.7 0.4 0.25 11.4 0.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger fn3 PF00041.21 KFP09316.1 - 1.4e-05 25.3 0.1 2.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain MLANA PF14991.6 KFP09316.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Pur_ac_phosph_N PF16656.5 KFP09316.1 - 0.023 15.3 0.1 0.042 14.4 0.1 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DUF2207 PF09972.9 KFP09316.1 - 0.17 10.6 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GCP_C_terminal PF04130.13 KFP09317.1 - 5.7e-42 144.2 7.9 5.7e-42 144.2 7.9 2.0 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP09317.1 - 1.7e-27 96.8 2.2 1.7e-27 96.8 2.2 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 KFP09317.1 - 0.00015 20.3 0.9 0.00081 17.9 0.1 2.4 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 DUF5601 PF18151.1 KFP09317.1 - 0.056 13.8 0.6 1.7 9.0 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) Na_H_Exchanger PF00999.21 KFP09318.1 - 9.4e-89 297.8 31.0 1.2e-88 297.5 31.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TBCC PF07986.12 KFP09320.1 - 3.7e-46 155.8 5.6 5.5e-46 155.2 5.6 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C NDK PF00334.19 KFP09320.1 - 0.00067 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CAP_C PF08603.11 KFP09320.1 - 0.0009 18.9 3.5 0.0016 18.1 3.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal zf-HC5HC2H_2 PF13832.6 KFP09321.1 - 5.1e-30 103.9 7.9 5.1e-30 103.9 7.9 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP09321.1 - 5.8e-25 87.4 6.1 5.8e-25 87.4 6.1 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP09321.1 - 2.9e-12 45.9 7.0 2.9e-12 45.9 7.0 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 KFP09321.1 - 2.2e-10 40.2 9.5 2.2e-10 40.2 9.5 3.5 2 1 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFP09321.1 - 2.6e-08 34.4 0.3 2.6e-08 34.4 0.3 3.3 4 1 0 4 4 4 1 Enhancer of polycomb-like C1_1 PF00130.22 KFP09321.1 - 0.0014 18.4 2.6 0.0014 18.4 2.6 3.8 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFP09321.1 - 0.013 15.5 7.5 0.013 15.5 7.5 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFP09321.1 - 0.24 11.0 15.0 4.5 6.9 7.4 3.4 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 KFP09321.1 - 0.6 10.5 23.8 1.3 9.4 7.9 3.6 3 0 0 3 3 3 0 C1 domain SGL PF08450.12 KFP09322.1 - 5.9e-65 219.3 0.1 6.6e-65 219.1 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFP09322.1 - 0.022 15.0 0.0 0.25 11.7 0.0 2.7 2 1 0 2 2 2 0 Two component regulator propeller NHL PF01436.21 KFP09322.1 - 0.077 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 NHL repeat SGL PF08450.12 KFP09323.1 - 9.5e-81 271.0 0.0 1.1e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFP09323.1 - 0.059 13.6 0.0 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 Two component regulator propeller Ldh_2 PF02615.14 KFP09323.1 - 0.2 10.8 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Kelch_6 PF13964.6 KFP09323.1 - 0.65 10.4 2.8 36 4.8 0.0 3.5 3 1 1 4 4 4 0 Kelch motif PI-PLC-X PF00388.19 KFP09324.1 - 0.0079 15.8 0.2 0.019 14.5 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain GTP-bdg_M PF16360.5 KFP09325.1 - 7.8e-21 74.5 6.5 1.8e-20 73.3 6.5 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 KFP09325.1 - 1.5e-14 54.4 0.9 1.2e-13 51.5 0.2 2.5 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 KFP09325.1 - 5.8e-13 48.9 0.0 1.7e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 KFP09325.1 - 0.00015 21.8 0.2 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain FeoB_N PF02421.18 KFP09325.1 - 0.00083 18.9 0.7 0.0033 16.9 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KFP09325.1 - 0.0031 17.3 0.2 0.069 12.9 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFP09325.1 - 0.0081 16.1 0.1 4.1 7.3 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KFP09325.1 - 0.011 15.2 0.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP09325.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain MnmE_helical PF12631.7 KFP09325.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 MnmE helical domain MobB PF03205.14 KFP09325.1 - 0.043 13.7 0.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KFP09325.1 - 0.053 14.0 0.7 0.11 12.9 0.2 2.1 1 1 1 2 2 2 0 ABC transporter MMR_HSR1_Xtn PF16897.5 KFP09325.1 - 0.053 13.5 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 KFP09325.1 - 0.06 12.7 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF483 PF04467.12 KFP09325.1 - 0.14 12.2 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF483) STAG PF08514.11 KFP09326.1 - 6.4e-34 116.3 0.1 1.9e-33 114.8 0.1 1.8 1 0 0 1 1 1 1 STAG domain AHSP PF09236.10 KFP09326.1 - 0.021 15.2 2.5 1.9 9.0 0.1 3.1 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein HEAT PF02985.22 KFP09326.1 - 0.029 14.6 0.0 46 4.6 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat DUF4020 PF13212.6 KFP09326.1 - 0.062 13.1 0.6 0.54 10.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) EF-hand_13 PF17958.1 KFP09327.1 - 1.8e-43 146.2 0.0 2.1e-41 139.6 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFP09327.1 - 1.3e-22 80.0 6.2 1.1e-20 73.8 2.2 4.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP09327.1 - 1.4e-08 33.6 0.2 0.073 12.7 0.0 6.0 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 KFP09327.1 - 5.1e-07 29.4 0.1 0.46 10.4 0.0 6.1 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP09327.1 - 6.4e-07 28.8 2.7 0.034 14.1 0.0 6.0 7 0 0 7 7 7 1 EF-hand domain EF-hand_5 PF13202.6 KFP09327.1 - 1.5e-06 27.4 0.1 0.0005 19.4 0.0 4.2 5 0 0 5 5 5 1 EF hand SPARC_Ca_bdg PF10591.9 KFP09327.1 - 0.053 13.8 5.3 2.3 8.6 0.3 3.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SBP_bac_6 PF13343.6 KFP09327.1 - 0.074 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Homeodomain PF00046.29 KFP09330.1 - 4.2e-25 87.4 2.9 7e-25 86.7 2.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP09330.1 - 0.0002 21.2 1.3 0.00071 19.4 0.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain MRP-L20 PF12824.7 KFP09330.1 - 0.0052 17.0 0.6 0.01 16.0 0.6 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Tissue_fac PF01108.17 KFP09332.1 - 0.025 14.4 0.5 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Tissue factor LAX PF15681.5 KFP09332.1 - 0.094 11.5 1.0 0.17 10.7 1.0 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X IL6Ra-bind PF09240.10 KFP09334.1 - 3.2e-20 72.3 2.0 6.1e-20 71.4 2.0 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding IL6Ra-bind PF09240.10 KFP09335.1 - 1.1e-20 73.9 0.1 1.7e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP09335.1 - 0.0013 18.9 1.5 0.0014 18.8 0.3 1.8 2 1 0 2 2 2 1 Erythropoietin receptor, ligand binding LIFR_N PF18207.1 KFP09335.1 - 0.035 14.5 0.1 0.085 13.2 0.1 1.7 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain IL6Ra-bind PF09240.10 KFP09336.1 - 3.1e-21 75.6 0.1 5.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP09336.1 - 0.0027 17.9 1.0 0.004 17.3 0.2 1.6 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding Mito_carr PF00153.27 KFP09338.1 - 6.4e-56 186.3 2.3 4.7e-23 80.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFP09338.1 - 0.071 12.3 0.1 0.43 9.7 0.1 1.9 2 0 0 2 2 2 0 Fuseless Maf PF02545.14 KFP09339.1 - 1.9e-44 151.4 0.0 3e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Maf-like protein Methyltransf_2 PF00891.18 KFP09339.1 - 2e-43 148.1 0.0 3.9e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFP09339.1 - 1e-31 108.7 0.1 3e-31 107.2 0.1 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.6 KFP09339.1 - 3.1e-05 24.6 0.0 0.00013 22.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP09339.1 - 0.00041 21.0 0.0 0.0015 19.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain 7tm_1 PF00001.21 KFP09340.1 - 1.1e-43 149.5 29.4 1.4e-43 149.1 29.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP09340.1 - 0.032 13.6 29.2 0.043 13.2 29.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv VHS PF00790.19 KFP09340.1 - 0.033 14.1 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain RRM_1 PF00076.22 KFP09341.1 - 0.0014 18.4 0.4 1.9 8.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_2 PF00891.18 KFP09342.1 - 2.2e-83 278.7 0.0 2.9e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFP09342.1 - 5.6e-35 119.2 0.2 1.3e-34 118.0 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.6 KFP09342.1 - 6.1e-07 30.1 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP09342.1 - 3.4e-05 23.8 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP09342.1 - 6.3e-05 23.5 0.0 0.00026 21.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP09342.1 - 0.0001 23.0 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP09342.1 - 0.0025 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 KFP09342.1 - 0.0045 17.0 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 KFP09342.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sld3_N PF18523.1 KFP09342.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Sld3 N-terminal domain Ig_3 PF13927.6 KFP09344.1 - 5e-09 36.6 0.0 3.8e-05 24.2 0.0 2.3 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP09344.1 - 6e-09 36.1 0.0 4.4e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP09344.1 - 0.00012 22.2 0.0 0.00096 19.3 0.1 2.1 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP09344.1 - 0.0055 16.7 0.0 0.12 12.4 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_C19orf38 PF17737.1 KFP09344.1 - 0.014 15.7 0.1 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 Ig domain in C19orf38 (HIDE1) V-set PF07686.17 KFP09344.1 - 0.019 15.2 1.2 0.2 11.8 0.0 2.4 2 1 1 3 3 3 0 Immunoglobulin V-set domain Big_3_5 PF16640.5 KFP09344.1 - 0.069 13.3 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Cobl PF09469.10 KFP09344.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain MBT PF02820.18 KFP09345.1 - 2.8e-94 309.5 2.8 9.4e-34 115.6 0.3 3.4 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KFP09345.1 - 6.2e-18 64.7 20.8 4.2e-14 52.4 8.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2HC type SAM_1 PF00536.30 KFP09345.1 - 8.6e-13 48.5 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ECM1 PF05782.11 KFP09345.1 - 0.013 14.4 2.7 0.027 13.4 2.7 1.5 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SAM_Ste50p PF09235.10 KFP09345.1 - 0.036 14.3 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif RRM_1 PF00076.22 KFP09346.1 - 6e-14 51.6 0.0 9e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP09346.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif 4_1_CTD PF05902.13 KFP09347.1 - 5.6e-34 116.4 2.1 5.6e-34 116.4 2.1 2.7 3 0 0 3 3 3 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFP09347.1 - 5.5e-25 87.6 0.0 1.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP09347.1 - 3.8e-22 78.0 0.3 1.8e-21 75.8 0.2 2.2 2 0 0 2 2 2 1 FERM N-terminal domain SAB PF04382.13 KFP09347.1 - 5.2e-21 74.4 2.3 1.7e-20 72.8 2.3 2.0 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFP09347.1 - 2.1e-20 73.3 0.0 6e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 KFP09347.1 - 2.4e-18 66.0 2.6 6.3e-18 64.6 2.6 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) Creatininase PF02633.14 KFP09347.1 - 0.012 15.1 0.5 1.3 8.4 0.2 2.4 1 1 0 2 2 2 0 Creatinine amidohydrolase AAR2 PF05282.11 KFP09348.1 - 4.6e-57 194.0 0.1 5.5e-57 193.8 0.1 1.0 1 0 0 1 1 1 1 AAR2 protein GKAP PF03359.13 KFP09349.1 - 1.8e-148 494.7 11.2 1.8e-148 494.7 11.2 3.2 4 0 0 4 4 4 1 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.11 KFP09350.1 - 0.00066 19.5 3.1 0.001 19.0 3.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_1 PF00036.32 KFP09351.1 - 4e-16 57.3 8.9 1.2e-07 30.7 1.6 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFP09351.1 - 1e-13 51.5 6.1 6.5e-07 29.7 0.2 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP09351.1 - 2.4e-12 45.7 9.1 7.5e-08 31.7 0.9 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFP09351.1 - 2.3e-07 30.5 7.4 0.0082 16.0 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP09351.1 - 3.2e-06 26.4 2.9 1.7e-05 24.1 1.5 2.6 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFP09351.1 - 0.00012 22.9 0.1 0.00082 20.2 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain GPHH PF16905.5 KFP09351.1 - 0.0015 18.2 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_9 PF14658.6 KFP09351.1 - 0.0017 18.6 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 KFP09351.1 - 0.0023 17.9 0.0 3.5 7.7 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Syntaxin PF00804.25 KFP09351.1 - 0.012 15.2 0.6 0.68 9.6 0.1 2.1 2 0 0 2 2 2 0 Syntaxin SPARC_Ca_bdg PF10591.9 KFP09351.1 - 0.026 14.8 0.6 0.06 13.7 0.1 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFP09351.1 - 0.062 13.6 0.0 21 5.4 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) Rab5ip PF07019.12 KFP09352.1 - 2.6e-18 66.4 10.3 2.9e-18 66.2 10.3 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2244 PF10003.9 KFP09352.1 - 0.022 14.4 0.8 0.022 14.4 0.8 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Clc-like PF07062.12 KFP09352.1 - 0.11 12.0 3.5 0.13 11.7 3.5 1.0 1 0 0 1 1 1 0 Clc-like Yip1 PF04893.17 KFP09352.1 - 0.47 10.1 9.3 2.8 7.6 9.0 1.9 1 1 0 1 1 1 0 Yip1 domain G_glu_transpept PF01019.21 KFP09353.1 - 7.3e-130 434.1 0.0 8.7e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DOR PF14839.6 KFP09354.1 - 9.6e-28 97.8 9.3 1e-26 94.4 3.3 2.1 1 1 1 2 2 2 2 DOR family PIG-U PF06728.13 KFP09355.1 - 1.2e-105 353.7 49.0 1.4e-105 353.5 49.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U TLD PF07534.16 KFP09356.1 - 8.5e-37 126.5 0.0 9.7e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 TLD HD PF01966.22 KFP09357.1 - 1.9e-15 57.2 0.0 7.3e-15 55.3 0.0 2.0 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 KFP09357.1 - 0.0025 17.6 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SNF2_N PF00176.23 KFP09358.1 - 5.9e-63 212.7 2.4 9.5e-63 212.0 2.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KFP09358.1 - 3.5e-25 87.7 3.3 2.8e-13 49.5 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFP09358.1 - 1.2e-16 61.0 0.0 3.7e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP09358.1 - 1.5e-07 31.6 0.1 7e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFP09358.1 - 1.8e-05 25.0 0.8 0.37 11.0 0.0 3.7 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain DEAD PF00270.29 KFP09358.1 - 0.00032 20.5 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFP09358.1 - 0.0058 15.8 0.1 0.034 13.3 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 BRK PF07533.16 KFP09358.1 - 0.027 14.1 0.9 0.23 11.1 0.2 2.5 2 0 0 2 2 2 0 BRK domain DUF3437 PF11919.8 KFP09358.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Ndr PF03096.14 KFP09359.1 - 1.6e-124 414.2 0.0 1.9e-124 414.0 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFP09359.1 - 5.6e-05 22.9 0.1 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold SH2 PF00017.24 KFP09360.1 - 2.3e-22 78.9 0.1 3.3e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP09360.1 - 0.002 17.9 0.1 0.016 15.0 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KFP09360.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09360.1 - 0.026 14.1 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_10 PF17902.1 KFP09360.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain DUF3776 PF12618.8 KFP09361.1 - 1.8e-26 92.5 19.0 1.8e-26 92.5 19.0 4.8 5 1 1 6 6 4 1 Protein of unknown function (DUF3776) Tudor_3 PF18115.1 KFP09361.1 - 3.3e-15 55.7 1.2 3.1e-13 49.3 0.5 3.0 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain PHD PF00628.29 KFP09361.1 - 2.7e-06 27.2 12.4 1.1e-05 25.2 12.4 2.2 1 0 0 1 1 1 1 PHD-finger Tudor_2 PF18104.1 KFP09361.1 - 1.6e-05 24.4 0.4 4.1e-05 23.2 0.4 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KFP09361.1 - 3.1e-05 24.0 0.2 0.00011 22.2 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) MBT PF02820.18 KFP09361.1 - 0.00028 21.2 0.6 0.0025 18.1 0.1 2.7 3 0 0 3 3 3 1 mbt repeat Tudor-knot PF11717.8 KFP09361.1 - 0.0021 17.9 2.2 0.011 15.6 1.4 2.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Rad9_Rad53_bind PF08605.10 KFP09361.1 - 0.012 15.9 2.5 0.57 10.4 0.1 3.2 4 0 0 4 4 4 0 Fungal Rad9-like Rad53-binding LBR_tudor PF09465.10 KFP09361.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Agenet PF05641.12 KFP09361.1 - 0.043 14.3 2.7 1.5 9.3 0.2 3.0 2 0 0 2 2 2 0 Agenet domain zf-C2H2 PF00096.26 KFP09361.1 - 0.35 11.4 10.4 0.042 14.3 5.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRM_1 PF00076.22 KFP09362.1 - 5.2e-42 141.5 0.0 4.6e-24 84.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFP09362.1 - 6e-27 94.6 0.3 1.7e-26 93.1 0.3 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFP09362.1 - 6.3e-05 22.7 0.0 0.013 15.3 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP09362.1 - 0.0062 16.1 0.0 0.45 10.1 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KFP09362.1 - 0.055 13.3 0.0 6.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) PRP38_assoc PF12871.7 KFP09362.1 - 0.91 10.2 57.7 0.18 12.4 50.2 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Romo1 PF10247.9 KFP09363.1 - 2.8e-26 91.7 22.0 3.3e-26 91.4 22.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KFP09363.1 - 0.0082 16.5 9.8 0.0095 16.3 9.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Aminotran_5 PF00266.19 KFP09364.1 - 5.4e-90 302.0 0.0 6.2e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP09364.1 - 7.7e-11 41.8 0.1 1.1e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFP09364.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFP09364.1 - 0.017 13.9 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KFP09364.1 - 0.027 13.0 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 KFP09365.1 - 4.5e-32 109.7 1.6 1.2e-08 34.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP09365.1 - 0.035 14.2 0.1 2.5 8.2 0.0 3.4 5 0 0 5 5 5 0 RNA binding motif RRM_8 PF11835.8 KFP09365.1 - 0.2 11.9 0.0 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 RRM-like domain Copine PF07002.16 KFP09366.1 - 1.5e-88 295.9 0.0 4.9e-88 294.2 0.0 1.8 2 0 0 2 2 2 1 Copine C2 PF00168.30 KFP09366.1 - 2.2e-23 82.5 0.0 5.6e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP09366.1 - 1.5e-06 28.5 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFP09366.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C2 PF00168.30 KFP09367.1 - 6.2e-40 135.7 0.0 3.5e-13 49.7 0.0 4.5 4 0 0 4 4 4 3 C2 domain FerB PF08150.12 KFP09367.1 - 6.8e-29 100.3 0.0 2e-28 98.8 0.0 1.9 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.12 KFP09367.1 - 1.4e-17 63.5 0.0 2.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain C2 PF00168.30 KFP09368.1 - 7.8e-21 74.3 0.0 1.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain Ferlin_C PF16165.5 KFP09369.1 - 5.9e-20 71.8 2.7 4.6e-10 39.7 0.8 2.2 1 1 1 2 2 2 2 Ferlin C-terminus COPIIcoated_ERV PF07970.12 KFP09370.1 - 1.4e-94 316.0 1.1 1.8e-94 315.7 1.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFP09370.1 - 2.4e-12 47.0 0.2 8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Insulin PF00049.18 KFP09371.1 - 0.011 16.7 0.1 0.012 16.5 0.1 1.3 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family DUF2368 PF10166.9 KFP09372.1 - 1.3e-56 189.9 0.1 1.5e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Ig_3 PF13927.6 KFP09373.1 - 4.2e-14 52.9 0.2 7e-06 26.6 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP09373.1 - 2.1e-11 43.9 0.3 5.5e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFP09373.1 - 2.5e-11 43.5 0.2 4.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP09373.1 - 2.3e-08 34.1 3.1 6.7e-05 23.0 0.2 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP09373.1 - 2.3e-07 31.0 0.3 0.011 16.0 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP09373.1 - 2.9e-05 24.0 0.1 0.00035 20.6 0.1 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP09373.1 - 0.0012 19.2 0.9 0.033 14.5 0.3 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.8 KFP09373.1 - 0.008 16.4 0.9 0.041 14.1 0.1 2.1 1 1 1 2 2 2 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFP09373.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain RIC1 PF07064.13 KFP09374.1 - 5e-80 268.5 1.1 7.9e-80 267.9 1.1 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KFP09374.1 - 0.0021 18.3 0.0 0.21 11.9 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 KFP09375.1 - 2.4e-47 161.2 0.0 3.4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFP09375.1 - 5.2e-05 23.0 0.1 0.00026 20.8 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 SGL PF08450.12 KFP09375.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Peptidase_M42 PF05343.14 KFP09375.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MFS_1 PF07690.16 KFP09376.1 - 7e-33 114.0 41.2 3.4e-22 78.8 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_5 PF18160.1 KFP09376.1 - 2.6 7.4 7.5 1 8.7 1.0 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PDZ_3 PF17815.1 KFP09380.1 - 0.079 12.8 0.2 0.82 9.5 0.0 1.9 1 1 1 2 2 2 0 PDZ domain GDC-P PF02347.16 KFP09381.1 - 6.9e-188 624.8 0.0 2.3e-176 586.9 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFP09381.1 - 1.3e-09 37.8 0.1 4.3e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFP09381.1 - 1.6e-05 24.1 0.2 7e-05 21.9 0.1 2.1 3 0 0 3 3 3 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 KFP09381.1 - 0.0052 15.5 0.2 0.29 9.8 0.1 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KFP09381.1 - 0.0068 15.6 0.0 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II RVT_1 PF00078.27 KFP09382.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Y_phosphatase PF00102.27 KFP09389.1 - 2.9e-166 550.7 0.3 3.6e-82 275.5 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP09389.1 - 9.6e-117 381.6 29.2 2.6e-16 59.7 0.1 9.6 10 0 0 10 10 9 8 Fibronectin type III domain Ig_3 PF13927.6 KFP09389.1 - 9.3e-40 135.1 1.2 1.1e-11 45.1 0.0 5.8 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 KFP09389.1 - 1.4e-39 134.1 0.0 9e-15 54.5 0.0 4.4 4 0 0 4 4 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP09389.1 - 8.7e-22 77.3 0.2 1.5e-07 31.6 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP09389.1 - 3.9e-19 69.0 17.9 0.014 15.9 0.3 9.5 8 2 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFP09389.1 - 2.1e-15 56.6 2.1 0.054 13.6 0.0 7.7 7 1 0 7 7 7 2 Fibronectin type III domain ig PF00047.25 KFP09389.1 - 5.7e-14 52.1 0.0 0.008 16.3 0.0 4.2 4 0 0 4 4 3 3 Immunoglobulin domain Interfer-bind PF09294.10 KFP09389.1 - 3.1e-11 43.5 0.1 0.83 10.0 0.0 7.2 7 0 0 7 7 6 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 KFP09389.1 - 3.4e-08 33.4 0.0 0.006 16.4 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.17 KFP09389.1 - 8.2e-08 32.4 0.0 0.021 15.0 0.0 5.1 3 1 0 3 3 3 2 Immunoglobulin V-set domain Y_phosphatase3 PF13350.6 KFP09389.1 - 8.8e-07 29.1 0.0 0.051 13.5 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP09389.1 - 1e-05 25.7 0.0 0.0057 16.8 0.0 2.8 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2369 PF10179.9 KFP09389.1 - 1.7e-05 25.1 0.9 14 6.2 0.0 6.8 8 0 0 8 8 7 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 KFP09389.1 - 3.3e-05 23.7 3.2 0.63 10.0 0.0 7.3 9 1 0 9 9 8 1 Fibronectin-III type domain Ig_C17orf99 PF17736.1 KFP09389.1 - 5e-05 23.3 0.0 1.4 9.0 0.0 4.7 5 0 0 5 5 5 1 C17orf99 Ig domain C2-set_2 PF08205.12 KFP09389.1 - 0.00014 21.9 0.1 2.9 8.0 0.0 3.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP09389.1 - 0.00043 20.6 0.0 0.21 12.0 0.0 3.8 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain CBM_4_9 PF02018.17 KFP09389.1 - 0.0016 18.7 2.5 25 5.1 0.0 5.7 6 0 0 6 6 6 0 Carbohydrate binding domain Glyco_hydro_36C PF16874.5 KFP09389.1 - 0.021 15.3 0.0 99 3.5 0.0 4.2 4 0 0 4 4 3 0 Glycosyl hydrolase family 36 C-terminal domain DUF4998 PF16389.5 KFP09389.1 - 0.061 12.9 0.2 8.8 5.9 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function Reeler PF02014.16 KFP09389.1 - 0.097 13.4 0.2 26 5.6 0.0 4.6 5 0 0 5 5 4 0 Reeler domain Glyco_hydro_46 PF01374.18 KFP09389.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 Big_5 PF13205.6 KFP09389.1 - 0.97 10.2 4.7 1.1e+02 3.5 0.2 4.6 3 1 1 4 4 4 0 Bacterial Ig-like domain DEAD PF00270.29 KFP09390.1 - 3.7e-38 131.0 0.0 7e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP09390.1 - 4.1e-31 107.6 0.1 7.8e-29 100.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP09390.1 - 3.9e-06 27.0 1.9 5.5e-06 26.5 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFP09390.1 - 0.0014 18.9 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain HEM4 PF02602.15 KFP09390.1 - 0.033 13.6 0.1 0.071 12.5 0.1 1.6 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD EF-hand_4 PF12763.7 KFP09391.1 - 0.032 14.2 0.0 0.093 12.7 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Myb_DNA-binding PF00249.31 KFP09392.1 - 2.6e-10 40.3 0.1 6.5e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KFP09392.1 - 4e-08 33.5 0.0 1.8e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KFP09392.1 - 5e-06 26.7 0.3 5.3e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain MYO10_CC PF16735.5 KFP09392.1 - 0.16 12.1 3.8 0.087 12.9 0.9 2.1 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain AATF-Che1 PF13339.6 KFP09393.1 - 1.8e-41 142.1 0.8 1.8e-41 142.1 0.8 2.9 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 KFP09393.1 - 5.5e-24 84.5 0.2 5.5e-24 84.5 0.2 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal CFC PF09443.10 KFP09394.1 - 2.3e-14 52.9 12.8 2.3e-14 52.9 12.8 2.3 3 0 0 3 3 3 1 Cripto_Frl-1_Cryptic (CFC) EGF PF00008.27 KFP09394.1 - 0.0075 16.5 6.5 0.0075 16.5 6.5 2.0 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFP09394.1 - 0.022 15.1 9.9 0.022 15.1 9.9 2.2 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 KFP09394.1 - 0.025 15.2 4.0 0.025 15.2 4.0 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF DUF3350 PF11830.8 KFP09395.1 - 0.009 16.3 1.4 0.009 16.3 1.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3350) MIT PF04212.18 KFP09395.1 - 0.077 13.1 1.1 0.1 12.7 1.1 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AhpC-TSA_2 PF13911.6 KFP09396.1 - 6.6e-19 68.1 0.0 7.9e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KFP09396.1 - 0.0023 17.6 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFP09396.1 - 0.0069 16.3 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DSPn PF14671.6 KFP09397.1 - 2.8e-57 193.1 3.1 3.3e-56 189.7 1.8 2.5 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFP09397.1 - 3.9e-15 55.8 0.0 7.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP09397.1 - 1.5e-05 25.1 0.0 3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP09397.1 - 3.3e-05 23.6 0.0 7.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP09397.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFP09397.1 - 0.048 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family HABP4_PAI-RBP1 PF04774.15 KFP09398.1 - 9e-16 58.8 16.9 3.6e-14 53.6 4.8 2.9 2 1 1 3 3 3 2 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFP09398.1 - 1.8e-08 35.2 4.9 1.8e-08 35.2 4.9 2.7 2 1 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal RPA_interact_M PF14767.6 KFP09398.1 - 0.032 14.8 0.2 0.081 13.5 0.2 1.7 1 0 0 1 1 1 0 Replication protein A interacting middle zf-H2C2_2 PF13465.6 KFP09399.1 - 1.3e-13 50.6 11.9 7.5e-07 29.3 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP09399.1 - 6.3e-10 38.9 4.4 2.5e-05 24.5 0.7 3.2 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP09399.1 - 2.4e-06 27.4 0.2 2.4e-06 27.4 0.2 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFP09399.1 - 5.6e-06 26.8 3.7 0.00041 20.9 0.4 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP09399.1 - 8.3e-05 22.8 0.2 0.0015 18.7 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP09399.1 - 0.00011 22.5 0.6 0.00053 20.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Tom37 PF10568.9 KFP09399.1 - 0.012 15.9 0.4 0.22 11.8 0.0 2.2 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein zf-C2H2_8 PF15909.5 KFP09399.1 - 0.023 15.0 3.2 0.11 12.9 3.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-CRD PF17979.1 KFP09399.1 - 0.03 14.4 10.8 3.5 7.7 10.8 2.1 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions TPT PF03151.16 KFP09400.1 - 3.4e-19 69.3 13.8 4.2e-19 69.0 13.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 KFP09400.1 - 2.9e-05 23.2 1.4 2.9e-05 23.2 1.4 2.4 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KFP09400.1 - 0.00013 21.3 15.4 0.00017 20.9 15.4 1.2 1 0 0 1 1 1 1 UAA transporter family Phage_holin_3_3 PF16083.5 KFP09400.1 - 0.14 12.3 3.9 1.5 9.0 0.2 2.6 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III RVT_1 PF00078.27 KFP09401.1 - 0.0013 18.3 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP09402.1 - 0.0018 17.8 0.0 0.004 16.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) VIGSSK PF14773.6 KFP09403.1 - 3.4e-08 33.5 0.3 1.2e-07 31.7 0.2 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal SNF2_N PF00176.23 KFP09404.1 - 8.4e-53 179.3 0.4 1.2e-52 178.8 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP09404.1 - 5.7e-21 74.9 0.0 1.4e-19 70.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP09404.1 - 3.3e-10 40.2 0.1 1.6e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP09404.1 - 1.3e-07 31.6 0.0 3.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFP09404.1 - 5.5e-07 29.1 0.1 1e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KFP09404.1 - 2.2e-06 27.1 1.4 0.00028 20.1 1.4 2.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFP09404.1 - 0.0014 18.4 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SMN PF06003.12 KFP09404.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AAA_34 PF13872.6 KFP09404.1 - 0.096 11.6 0.0 4.7 6.0 0.0 2.7 4 0 0 4 4 4 0 P-loop containing NTP hydrolase pore-1 SEC-C PF02810.15 KFP09404.1 - 0.37 10.8 8.0 0.98 9.4 8.0 1.8 1 0 0 1 1 1 0 SEC-C motif Patched PF02460.18 KFP09405.1 - 3.4e-74 250.4 19.3 1.9e-42 145.4 1.3 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KFP09405.1 - 2.6e-43 147.5 4.0 2.6e-43 147.5 4.0 2.7 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Fanconi_C PF02106.15 KFP09406.1 - 1.7e-256 852.3 24.1 2e-256 852.1 24.1 1.0 1 0 0 1 1 1 1 Fanconi anaemia group C protein EF-hand_2 PF09068.11 KFP09406.1 - 0.019 15.1 6.7 0.61 10.2 0.1 3.6 2 1 0 2 2 2 0 EF hand FBPase PF00316.20 KFP09407.1 - 5.7e-62 208.5 0.2 7.7e-62 208.1 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFP09407.1 - 3.5e-05 23.5 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family SRAP PF02586.14 KFP09407.1 - 0.22 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 SOS response associated peptidase (SRAP) FBPase PF00316.20 KFP09408.1 - 3e-73 245.3 0.1 4.2e-73 244.9 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KFP09408.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 2 0 0 2 2 2 1 Inositol monophosphatase family Peptidase_C1 PF00112.23 KFP09409.1 - 7.8e-89 297.5 3.4 1.1e-88 297.0 3.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KFP09409.1 - 6.2e-13 49.0 1.7 1.2e-12 48.1 1.7 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KFP09409.1 - 1.7e-06 27.1 2.9 0.0002 20.3 1.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Lipocalin_8 PF16585.5 KFP09409.1 - 0.033 14.6 0.6 0.062 13.7 0.6 1.4 1 0 0 1 1 1 0 Lipocalin-like domain Styelin PF17562.2 KFP09409.1 - 0.061 13.7 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Styelin Death PF00531.22 KFP09410.1 - 3.3e-22 78.4 0.5 9.3e-21 73.8 0.0 3.2 3 1 0 3 3 3 1 Death domain COR PF16095.5 KFP09410.1 - 2.5e-08 34.0 0.1 4.1e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase PF00069.25 KFP09411.1 - 1.3e-70 237.8 0.0 1.9e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KFP09411.1 - 8e-53 177.0 5.1 3.7e-15 56.3 0.1 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09411.1 - 3.7e-45 151.7 5.1 3.3e-09 37.1 0.0 7.5 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP09411.1 - 2.8e-44 148.6 11.8 3.3e-09 36.8 0.0 7.5 1 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KFP09411.1 - 1.1e-38 130.0 8.0 5.2e-06 26.7 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 KFP09411.1 - 1.4e-36 120.3 8.6 5.3e-05 23.3 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Pkinase_Tyr PF07714.17 KFP09411.1 - 5.7e-34 117.6 0.0 9.5e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP09411.1 - 7.1e-06 25.5 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP09411.1 - 0.00012 21.7 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Roc PF08477.13 KFP09411.1 - 0.0035 17.5 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KFP09411.1 - 0.017 15.7 0.0 0.064 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Choline_kinase PF01633.20 KFP09411.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFP09411.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3847 PF12958.7 KFP09411.1 - 0.06 13.5 0.2 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) ABC_tran PF00005.27 KFP09411.1 - 0.069 13.7 0.0 0.24 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter bZIP_1 PF00170.21 KFP09412.1 - 1.5e-14 53.8 16.0 4.2e-14 52.4 15.9 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP09412.1 - 4.5e-09 36.2 10.7 4.5e-09 36.2 10.7 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP09412.1 - 9.4e-07 29.3 10.7 2.1e-06 28.2 10.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFP09412.1 - 0.0029 18.0 2.8 0.011 16.1 2.8 2.0 1 0 0 1 1 1 1 Cell division protein ZapB Fmp27_WPPW PF10359.9 KFP09412.1 - 0.0058 15.5 0.5 0.0073 15.2 0.5 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Goodbye PF17109.5 KFP09412.1 - 0.011 16.1 0.5 0.027 14.9 0.5 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain HAUS6_N PF14661.6 KFP09412.1 - 0.023 14.3 2.7 0.096 12.2 3.2 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 KFP09412.1 - 0.03 14.8 5.7 0.076 13.6 5.7 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KFP09412.1 - 0.042 14.1 7.4 0.083 13.1 7.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KFP09412.1 - 0.045 14.2 2.1 0.13 12.7 2.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) JMY PF15871.5 KFP09412.1 - 0.053 12.8 5.7 0.082 12.2 5.7 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein TPR_MLP1_2 PF07926.12 KFP09412.1 - 0.053 13.6 10.1 0.1 12.6 10.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 KFP09412.1 - 0.092 12.3 5.2 0.19 11.3 5.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.8 KFP09412.1 - 0.13 12.3 10.6 0.26 11.4 10.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KFP09412.1 - 0.15 11.9 7.3 0.26 11.1 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MCU PF04678.13 KFP09412.1 - 0.15 12.2 0.7 0.29 11.2 0.7 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2207 PF09972.9 KFP09412.1 - 0.2 10.4 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TBCA PF02970.16 KFP09412.1 - 0.23 11.8 7.7 0.5 10.7 7.7 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A FOXP-CC PF16159.5 KFP09412.1 - 0.24 12.1 2.2 0.6 10.8 2.2 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF4404 PF14357.6 KFP09412.1 - 0.42 11.3 4.6 0.96 10.1 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 KFP09412.1 - 0.67 10.0 4.8 1.1 9.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PTN_MK_C PF01091.18 KFP09413.1 - 9.7e-28 96.4 9.4 9.7e-28 96.4 9.4 3.0 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.13 KFP09413.1 - 2.2e-26 91.8 16.6 2.2e-26 91.8 16.6 2.7 3 1 0 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain UPF0239 PF06783.11 KFP09413.1 - 5.4 7.3 8.5 6.7 7.0 0.1 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0239) 7tm_1 PF00001.21 KFP09415.1 - 2.6e-73 246.6 7.4 3.8e-73 246.0 7.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP09415.1 - 1.7e-06 27.9 12.1 1.7e-06 27.9 12.1 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP09415.1 - 4.9e-06 26.5 5.5 4.9e-06 26.5 5.5 2.5 2 1 0 3 3 3 1 Olfactory receptor 5HT_transport_N PF03491.13 KFP09415.1 - 1.9 8.7 4.3 6 7.1 0.1 2.5 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Myc_N PF01056.18 KFP09415.1 - 8 6.3 11.4 11 5.8 11.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ank_5 PF13857.6 KFP09418.1 - 1.2e-17 63.7 0.0 3.4e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP09418.1 - 2.3e-17 63.1 0.1 4.3e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP09418.1 - 2.5e-14 53.6 0.1 3.2e-13 50.1 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP09418.1 - 1.1e-13 51.0 0.1 9.2e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP09418.1 - 2.9e-12 45.6 0.1 7e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat FAM180 PF15173.6 KFP09420.1 - 1.1e-60 203.5 0.5 1.3e-60 203.4 0.5 1.0 1 0 0 1 1 1 1 FAM180 family RRP36 PF06102.12 KFP09420.1 - 0.06 13.3 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Na_sulph_symp PF00939.19 KFP09421.1 - 4.2e-101 339.3 21.0 5.4e-101 339.0 21.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP09421.1 - 1.7e-32 112.8 25.5 6.3e-17 61.7 0.0 3.4 3 1 1 4 4 4 3 Citrate transporter C2 PF00168.30 KFP09423.1 - 1.1e-53 179.8 0.1 2e-27 95.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFP09423.1 - 1.3e-05 25.2 0.1 0.24 11.3 0.0 3.2 3 1 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFP09423.1 - 0.0039 16.8 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain Arm PF00514.23 KFP09424.1 - 1.8e-34 116.7 0.8 1.8e-09 37.3 0.0 7.4 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KFP09424.1 - 6.8e-07 29.0 0.6 0.0023 17.5 0.0 2.5 2 1 0 2 2 2 2 Armadillo-like Atx10homo_assoc PF09759.9 KFP09424.1 - 0.00018 21.5 0.1 0.016 15.2 0.1 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KFP09424.1 - 0.00087 19.3 0.1 7 7.2 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KFP09424.1 - 0.0075 16.6 0.7 0.085 13.3 0.2 2.6 2 0 0 2 2 2 1 HEAT repeats V-ATPase_H_N PF03224.14 KFP09424.1 - 0.01 15.2 0.1 0.38 10.0 0.0 2.3 2 0 0 2 2 2 1 V-ATPase subunit H Cupin_7 PF12973.7 KFP09424.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 ChrR Cupin-like domain Symplekin_C PF12295.8 KFP09424.1 - 0.14 12.2 0.7 1.8 8.6 0.1 2.5 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal DUF383 PF04063.14 KFP09424.1 - 0.16 11.6 2.7 14 5.3 0.0 3.6 3 1 2 5 5 5 0 Domain of unknown function (DUF383) HEAT_EZ PF13513.6 KFP09424.1 - 0.17 12.4 1.0 10 6.7 0.0 3.8 4 1 1 5 5 5 0 HEAT-like repeat Dynamin_M PF01031.20 KFP09426.1 - 2.9e-104 348.3 0.1 9.2e-104 346.6 0.0 1.9 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KFP09426.1 - 1.7e-50 171.3 0.5 4.4e-50 170.0 0.1 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KFP09426.1 - 1.8e-31 108.2 2.7 1.8e-31 108.2 2.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain RhoGEF PF00621.20 KFP09427.1 - 8.9e-46 156.4 0.4 8.9e-46 156.4 0.4 1.7 2 0 0 2 2 1 1 RhoGEF domain PH PF00169.29 KFP09427.1 - 1e-25 90.2 0.5 1.4e-12 48.1 0.0 3.3 2 1 1 3 3 3 2 PH domain FYVE PF01363.21 KFP09427.1 - 6.8e-18 64.6 11.4 1.7e-17 63.3 11.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger IQ_SEC7_PH PF16453.5 KFP09427.1 - 7.3e-08 32.5 0.3 1.2e-06 28.5 0.3 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFP09427.1 - 4.4e-05 23.4 7.2 0.013 15.4 2.9 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH_6 PF15406.6 KFP09427.1 - 0.00069 19.9 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain FYVE_2 PF02318.16 KFP09427.1 - 0.0015 18.7 11.6 0.0051 17.0 10.9 2.3 1 1 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.6 KFP09427.1 - 0.0039 17.6 1.3 1.3 9.5 0.0 3.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFP09427.1 - 0.0045 17.3 0.4 0.81 10.1 0.1 3.1 3 0 0 3 3 3 1 Plant pleckstrin homology-like region Presenilin PF01080.17 KFP09427.1 - 0.036 12.8 1.6 0.064 12.0 1.6 1.4 1 0 0 1 1 1 0 Presenilin PH_5 PF15405.6 KFP09427.1 - 0.078 13.1 0.2 8.9 6.4 0.1 3.1 1 1 1 2 2 2 0 Pleckstrin homology domain zf-RING_UBOX PF13445.6 KFP09427.1 - 0.13 12.3 6.4 0.48 10.5 6.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFP09427.1 - 0.24 11.4 12.7 0.54 10.3 12.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain PH_16 PF17838.1 KFP09427.1 - 0.24 11.2 2.1 3.4 7.5 0.1 2.8 3 0 0 3 3 3 0 PH domain DUF4162 PF13732.6 KFP09427.1 - 2.1 9.1 5.9 3.2 8.5 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF4162) IBR PF01485.21 KFP09427.1 - 6 7.2 13.3 23 5.3 13.0 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain WD40 PF00400.32 KFP09429.1 - 8.6e-53 175.1 25.4 3.4e-10 40.3 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09429.1 - 4.3e-29 100.7 2.1 6.9e-08 32.7 0.1 6.3 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP09429.1 - 1.5e-11 44.5 0.5 0.001 19.0 0.1 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KFP09429.1 - 6e-10 38.7 0.1 3.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 LisH WD40_like PF17005.5 KFP09429.1 - 4.1e-05 23.1 0.0 0.08 12.3 0.0 3.1 4 1 0 4 4 4 2 WD40-like domain Coatomer_WDAD PF04053.14 KFP09429.1 - 0.00013 21.2 0.0 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KFP09429.1 - 0.00014 20.9 1.3 0.77 8.6 0.0 3.4 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP09429.1 - 0.0068 15.1 4.7 0.68 8.5 0.0 3.8 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFP09429.1 - 0.031 14.2 0.0 0.49 10.4 0.0 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_hydro_11 PF00457.17 KFP09429.1 - 0.052 13.2 1.2 1.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 PCuAC PF04314.13 KFP09429.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Copper chaperone PCu(A)C IKI3 PF04762.12 KFP09429.1 - 0.2 9.6 0.2 4.9 5.0 0.0 2.5 2 1 1 3 3 3 0 IKI3 family Peptidase_M28 PF04389.17 KFP09430.1 - 2.1e-06 27.6 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 KFP09430.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain COesterase PF00135.28 KFP09432.1 - 1.8e-125 419.8 0.0 2.2e-125 419.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sarcoglycan_2 PF05510.13 KFP09432.1 - 0.015 14.1 0.0 0.034 12.9 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Abhydrolase_3 PF07859.13 KFP09432.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold TPR_1 PF00515.28 KFP09435.1 - 2e-34 116.0 19.1 5.8e-05 22.7 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat DUF1736 PF08409.11 KFP09435.1 - 3.4e-33 113.4 3.7 6.9e-33 112.5 3.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KFP09435.1 - 3.4e-29 98.6 17.3 1.1e-05 25.1 0.3 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFP09435.1 - 1.2e-27 93.8 9.7 5.7e-05 23.0 0.2 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFP09435.1 - 1.2e-26 91.1 20.9 6.1e-06 26.3 0.3 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFP09435.1 - 1.4e-24 86.5 5.7 1.1e-07 32.3 0.1 4.8 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFP09435.1 - 1.4e-24 85.4 17.6 2.2e-06 27.2 0.3 8.0 2 2 6 8 8 8 5 TPR repeat TPR_12 PF13424.6 KFP09435.1 - 9.1e-19 67.5 13.7 1.5e-06 28.4 0.2 5.8 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFP09435.1 - 5.5e-16 57.9 8.2 0.0044 17.7 0.1 7.9 3 1 6 9 9 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFP09435.1 - 2.1e-14 52.8 22.1 5.7e-05 22.9 0.5 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP09435.1 - 9e-14 51.7 10.0 2.7e-06 27.8 0.7 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFP09435.1 - 6.7e-10 38.3 6.0 4.5 7.5 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFP09435.1 - 8.2e-05 22.9 0.3 3.8 8.4 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP09435.1 - 0.00029 20.2 7.4 0.011 15.0 1.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP09435.1 - 0.00046 19.7 5.0 0.13 11.6 0.3 3.2 1 1 2 3 3 3 2 MalT-like TPR region NARP1 PF12569.8 KFP09435.1 - 0.0018 17.2 3.0 0.05 12.5 0.2 2.5 1 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KFP09435.1 - 0.0044 17.6 3.2 16 6.4 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP09435.1 - 0.008 16.3 3.9 0.11 12.6 0.1 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFP09435.1 - 0.075 13.4 3.0 0.99 9.8 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFP09435.1 - 0.15 12.5 1.8 0.84 10.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain FAT PF02259.23 KFP09435.1 - 0.17 11.1 5.3 0.029 13.6 1.4 1.8 2 0 0 2 2 2 0 FAT domain ANAPC3 PF12895.7 KFP09435.1 - 0.42 10.9 5.5 3.2 8.1 0.4 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KFP09435.1 - 5 7.3 5.8 14 5.8 0.8 3.8 3 2 1 4 4 3 0 MIT (microtubule interacting and transport) domain GGACT PF06094.12 KFP09436.1 - 1.4e-22 80.6 0.2 1.6e-22 80.4 0.2 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KFP09436.1 - 0.065 13.6 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 AIG2-like family Sulfotransfer_1 PF00685.27 KFP09437.1 - 5.7e-26 91.6 0.4 7.8e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP09437.1 - 2.1e-17 64.2 1.0 5.3e-10 40.0 0.0 3.1 2 1 1 3 3 3 2 Sulfotransferase family TM231 PF10149.9 KFP09438.1 - 3.8e-102 341.7 0.4 4.2e-102 341.5 0.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Atg8 PF02991.16 KFP09439.1 - 7.5e-41 138.5 0.1 8.3e-41 138.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFP09439.1 - 2.2e-06 28.0 0.0 2.5e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CTXphi_pIII-N1 PF16710.5 KFP09439.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII A_deamin PF02137.18 KFP09440.1 - 5.4e-121 404.1 0.3 7.4e-121 403.6 0.3 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain tRNA-synt_2 PF00152.20 KFP09441.1 - 6.3e-62 209.5 0.0 6.3e-48 163.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP09441.1 - 1.4e-16 60.2 0.0 6.8e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFP09441.1 - 5.9e-07 29.2 0.1 0.0069 15.9 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Sulfotransfer_1 PF00685.27 KFP09442.1 - 6.4e-27 94.7 0.1 9e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP09442.1 - 1.1e-17 65.2 1.7 2.9e-10 40.9 0.0 3.0 2 1 1 3 3 3 2 Sulfotransferase family Aminotran_1_2 PF00155.21 KFP09443.1 - 4.7e-74 249.7 0.0 5.4e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TAT_ubiq PF07706.12 KFP09443.1 - 2.8e-18 65.9 0.9 4.5e-18 65.2 0.9 1.4 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Aminotran_5 PF00266.19 KFP09443.1 - 3.1e-06 26.4 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP09443.1 - 1.2e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFP09443.1 - 9.6e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFP09443.1 - 0.0033 16.0 0.0 0.005 15.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 KFP09443.1 - 0.13 11.1 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MARVEL PF01284.23 KFP09444.1 - 1e-05 25.6 1.7 1.3e-05 25.3 1.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF997 PF06196.12 KFP09444.1 - 0.13 12.3 4.5 0.077 13.0 2.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF997) B12D PF06522.11 KFP09444.1 - 5.9 6.8 8.0 2.2 8.1 0.7 2.6 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit LRR_8 PF13855.6 KFP09445.1 - 6.4e-40 134.7 69.9 7.6e-09 35.2 5.3 9.6 5 2 2 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFP09445.1 - 1.5e-30 104.7 73.7 4.6e-07 30.1 3.9 12.5 4 2 11 16 16 16 16 Leucine Rich repeats (2 copies) PP2C PF00481.21 KFP09445.1 - 8.6e-26 91.1 0.0 1.4e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.33 KFP09445.1 - 2.4e-05 24.3 64.1 3.7 8.5 0.3 16.6 15 2 0 15 15 15 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP09445.1 - 8.2e-05 22.4 56.4 1.8 8.8 0.2 14.9 15 1 0 15 15 15 3 Leucine Rich repeat PH PF00169.29 KFP09445.1 - 0.0018 18.7 0.0 0.0039 17.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Gliadin PF13016.6 KFP09445.1 - 0.22 11.9 2.5 2.5 8.6 1.1 2.7 2 0 0 2 2 2 0 Cys-rich Gliadin N-terminal Adaptin_N PF01602.20 KFP09446.1 - 3.3e-154 514.3 8.7 4e-154 514.0 8.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFP09446.1 - 1.7e-35 121.6 5.3 3e-35 120.9 5.3 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFP09446.1 - 6.2e-13 49.1 3.7 1.5e-09 38.1 0.2 3.5 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AXH PF08517.12 KFP09447.1 - 3.3e-41 140.4 0.0 6.1e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) zf-C2H2_4 PF13894.6 KFP09448.1 - 1.8e-07 31.4 6.8 0.0026 18.5 0.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFP09448.1 - 5.5e-07 29.8 2.9 0.99 9.9 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP09448.1 - 0.00019 21.6 4.4 0.0014 18.9 4.4 2.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFP09448.1 - 0.00094 19.5 12.4 0.0052 17.2 0.0 3.7 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KFP09448.1 - 0.0025 17.6 1.6 2.4 8.1 0.1 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFP09448.1 - 0.0031 17.2 0.3 0.0031 17.2 0.3 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KFP09448.1 - 0.0041 17.5 0.4 2.6 8.6 0.0 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP09448.1 - 0.011 16.0 0.1 15 6.0 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFP09448.1 - 0.012 15.6 3.0 0.096 12.7 2.3 2.6 2 1 1 3 3 3 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KFP09448.1 - 0.052 13.4 2.6 1 9.3 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KFP09448.1 - 0.37 10.7 7.2 23 4.9 0.6 3.9 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-C2H2_6 PF13912.6 KFP09448.1 - 0.38 10.8 6.5 4.6 7.3 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-FPG_IleRS PF06827.14 KFP09448.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.1 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Peptidase_S46 PF10459.9 KFP09448.1 - 5.5 5.5 9.7 7.8 5.0 9.7 1.1 1 0 0 1 1 1 0 Peptidase S46 PhnA_Zn_Ribbon PF08274.12 KFP09448.1 - 5.8 7.0 12.7 11 6.1 0.1 3.8 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Ist1 PF03398.14 KFP09450.1 - 7.9e-63 211.3 4.0 9.6e-63 211.0 4.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DHO_dh PF01180.21 KFP09451.1 - 4.6e-100 334.6 0.0 5.2e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KFP09451.1 - 0.0027 16.8 0.5 0.0063 15.6 0.5 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KFP09451.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase HA2 PF04408.23 KFP09452.1 - 7.7e-20 71.2 0.0 7.7e-20 71.2 0.0 4.7 4 1 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP09452.1 - 1.5e-16 60.5 0.0 3.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP09452.1 - 8.9e-14 51.8 0.0 2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP09452.1 - 3.4e-07 30.2 0.0 8.7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP09452.1 - 2.2e-05 24.8 0.0 6.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFP09452.1 - 0.00055 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP09452.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFP09452.1 - 0.0026 16.9 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KFP09452.1 - 0.0026 17.7 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.16 KFP09452.1 - 0.013 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KFP09452.1 - 0.027 14.1 0.1 0.07 12.8 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KFP09452.1 - 0.064 13.6 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFP09452.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFP09452.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.2 3 0 0 3 3 1 0 AAA domain BicD PF09730.9 KFP09453.1 - 0.0034 15.9 11.7 0.0037 15.8 11.7 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Myosin_tail_1 PF01576.19 KFP09453.1 - 0.0053 14.6 18.7 0.0059 14.5 18.7 1.1 1 0 0 1 1 1 1 Myosin tail Golgin_A5 PF09787.9 KFP09453.1 - 0.0063 16.0 21.8 0.0074 15.8 21.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 EzrA PF06160.12 KFP09453.1 - 0.035 12.3 12.5 0.0092 14.2 8.9 1.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 KFP09453.1 - 0.055 13.9 19.6 0.5 10.8 19.6 1.9 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 KFP09453.1 - 0.11 11.3 22.0 0.15 10.9 8.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KFP09453.1 - 0.18 12.0 23.2 1.5 9.0 23.2 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 KFP09453.1 - 0.18 11.9 18.3 0.037 14.1 11.9 2.1 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 KFP09453.1 - 0.19 10.8 18.6 0.22 10.6 18.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rsd_AlgQ PF04353.13 KFP09453.1 - 0.22 11.5 9.3 0.19 11.7 4.6 2.0 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF3972 PF13118.6 KFP09453.1 - 0.23 11.9 7.6 4.9 7.6 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) KASH_CCD PF14662.6 KFP09453.1 - 0.29 10.9 18.4 0.39 10.5 18.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 KFP09453.1 - 0.32 11.9 20.9 0.17 12.8 14.9 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Lebercilin PF15619.6 KFP09453.1 - 0.62 9.7 24.4 2.6 7.7 24.4 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 KFP09453.1 - 0.79 10.1 20.7 4.6 7.7 20.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 KFP09453.1 - 0.92 9.7 21.9 3.1 8.0 21.9 1.7 1 1 0 1 1 1 0 Tropomyosin like Leu_zip PF15294.6 KFP09453.1 - 1 8.8 14.8 1.2 8.6 14.8 1.1 1 0 0 1 1 1 0 Leucine zipper TMF_TATA_bd PF12325.8 KFP09453.1 - 1.3 9.2 20.8 0.38 11.0 13.4 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KFP09453.1 - 1.3 8.3 21.2 1.8 7.9 15.6 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nup88 PF10168.9 KFP09453.1 - 1.7 6.4 17.1 2 6.1 17.1 1.0 1 0 0 1 1 1 0 Nuclear pore component JIP_LZII PF16471.5 KFP09453.1 - 1.7 8.9 17.6 0.59 10.4 2.1 3.1 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Macoilin PF09726.9 KFP09453.1 - 1.9 6.9 17.5 2.4 6.6 17.5 1.1 1 0 0 1 1 1 0 Macoilin family Uso1_p115_C PF04871.13 KFP09453.1 - 2 8.8 21.4 0.088 13.2 9.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BST2 PF16716.5 KFP09453.1 - 3.1 8.4 20.7 8.6 7.0 12.8 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 UPF0242 PF06785.11 KFP09453.1 - 3.8 7.6 21.5 4.9 7.2 21.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KFP09453.1 - 4.4 6.6 14.9 5.1 6.4 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 KFP09453.1 - 5.2 7.3 16.9 8.3e+02 0.2 16.8 2.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 NUDE_C PF04880.13 KFP09453.1 - 5.5 7.4 14.8 4.2 7.8 9.0 2.2 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region OmpH PF03938.14 KFP09453.1 - 6.6 7.1 21.3 12 6.2 21.4 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ERM PF00769.19 KFP09453.1 - 7.8 6.2 28.9 9.9 5.9 28.9 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SseC PF04888.12 KFP09453.1 - 10 5.6 11.7 0.88 9.1 7.3 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family WD40 PF00400.32 KFP09464.1 - 1.5e-05 25.7 5.3 0.2 12.6 0.2 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Reprolysin PF01421.19 KFP09465.1 - 1.2e-41 142.8 2.3 1.2e-41 142.8 2.3 2.3 2 1 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP09465.1 - 4e-30 104.6 8.1 4e-30 104.6 8.1 3.7 3 1 0 3 3 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP09465.1 - 5.7e-23 81.7 1.2 2.8e-22 79.5 0.0 2.4 2 0 0 2 2 2 1 Reprolysin family propeptide Disintegrin PF00200.23 KFP09465.1 - 3.6e-18 66.1 28.5 3.6e-18 66.1 28.5 4.7 3 1 0 3 3 2 1 Disintegrin Reprolysin_5 PF13688.6 KFP09465.1 - 3.3e-15 56.8 1.6 6.7e-15 55.7 1.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP09465.1 - 1.9e-10 41.3 0.1 3.2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP09465.1 - 6.4e-07 29.2 0.1 1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP09465.1 - 2.6e-05 24.2 0.5 4.4e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFP09465.1 - 0.00037 20.8 12.3 0.00037 20.8 12.3 6.2 6 2 2 8 8 4 1 EGF-like domain Astacin PF01400.24 KFP09465.1 - 0.0081 15.8 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFP09465.1 - 0.01 15.7 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 Matrixin ADAM_CR_2 PF17771.1 KFP09465.1 - 0.01 16.4 1.8 0.01 16.4 1.8 6.9 3 2 3 6 6 4 0 ADAM cysteine-rich domain Peptidase_M57 PF12388.8 KFP09465.1 - 0.16 11.5 0.3 0.28 10.8 0.3 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase PGM_PMM_I PF02878.16 KFP09466.1 - 2.2e-35 121.4 0.0 6.6e-35 119.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFP09466.1 - 6.7e-25 87.7 0.0 1.4e-23 83.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KFP09466.1 - 8.1e-13 48.6 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KFP09466.1 - 2.3e-07 30.9 0.1 1.4e-06 28.4 0.0 2.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CDC27 PF09507.10 KFP09468.1 - 1.1e-128 430.2 33.3 1.3e-128 430.1 33.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Tet_JBP PF12851.7 KFP09471.1 - 3.3e-136 454.0 5.3 3.3e-136 454.0 5.3 2.4 2 1 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Pyrophosphatase PF00719.19 KFP09472.1 - 8.2e-58 194.7 0.8 1e-57 194.4 0.8 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-RING_12 PF17976.1 KFP09472.1 - 0.023 15.0 0.3 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RhoGEF PF00621.20 KFP09474.1 - 5.4e-19 69.1 1.3 7.1e-19 68.8 1.3 1.2 1 0 0 1 1 1 1 RhoGEF domain Tuberin PF03542.16 KFP09474.1 - 0.041 13.0 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Tuberin RhoGEF PF00621.20 KFP09475.1 - 1.3e-13 51.6 0.1 1.3e-13 51.6 0.1 2.8 2 1 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 KFP09475.1 - 3.3e-11 42.7 0.0 6.5e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFP09475.1 - 1e-09 38.1 0.1 3.3e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFP09475.1 - 1.3e-09 37.5 0.3 4.7e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 KFP09475.1 - 0.021 15.1 0.5 0.83 10.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain tRNA_bind_3 PF17176.4 KFP09475.1 - 0.021 15.1 0.4 0.16 12.3 0.1 2.5 2 0 0 2 2 2 0 tRNA-binding domain PHD PF00628.29 KFP09476.1 - 1.7e-09 37.4 9.7 2.8e-09 36.7 9.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KFP09476.1 - 5.7e-05 22.9 3.0 5.7e-05 22.9 3.0 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KFP09476.1 - 0.0018 17.8 4.7 0.0039 16.7 4.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KFP09476.1 - 0.0043 17.0 5.9 0.008 16.2 5.9 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 KFP09476.1 - 0.0054 16.6 3.8 0.013 15.4 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_4 PF16866.5 KFP09476.1 - 0.024 14.7 9.7 0.081 13.0 9.7 2.0 1 1 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 KFP09476.1 - 0.043 13.4 6.5 0.17 11.5 6.6 1.9 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-4CXXC_R1 PF10497.9 KFP09476.1 - 0.11 12.7 4.9 0.22 11.8 4.9 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.16 KFP09476.1 - 0.15 12.3 5.6 0.3 11.3 5.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zinc_ribbon_15 PF17032.5 KFP09476.1 - 0.17 12.7 3.6 0.36 11.6 3.6 1.5 1 0 0 1 1 1 0 zinc-ribbon family Zf_RING PF16744.5 KFP09476.1 - 4.8 7.4 9.1 18 5.5 9.1 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KFP09476.1 - 10 6.6 9.0 22 5.5 9.1 1.6 1 1 0 1 1 1 0 Ring finger domain Methyltransf_32 PF13679.6 KFP09477.1 - 2.1e-11 44.0 3.8 2.7e-10 40.5 3.8 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP09477.1 - 1.3e-07 31.5 0.1 2.5e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KFP09477.1 - 2.1e-05 24.2 1.4 0.058 12.9 0.9 2.7 1 1 1 2 2 2 2 Methyltransferase TRM13 GidB PF02527.15 KFP09477.1 - 2.9e-05 23.5 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G GST_C_2 PF13410.6 KFP09477.1 - 0.0001 22.2 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_4 PF02390.17 KFP09477.1 - 0.00083 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFP09477.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFP09477.1 - 0.0021 18.7 0.1 0.0056 17.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP09477.1 - 0.0093 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GST_C_3 PF14497.6 KFP09477.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_16 PF10294.9 KFP09477.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase EGF_CA PF07645.15 KFP09478.1 - 1.2e-23 83.1 61.7 2.1e-10 40.6 3.7 5.6 4 1 1 5 5 5 3 Calcium-binding EGF domain MAM PF00629.23 KFP09478.1 - 1.2e-19 70.8 0.0 2.7e-19 69.7 0.0 1.6 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu cEGF PF12662.7 KFP09478.1 - 1.2e-18 66.7 46.2 1.9e-07 30.9 0.9 5.9 6 0 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP09478.1 - 1.1e-08 35.2 76.0 4.7e-05 23.6 9.3 5.5 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP09478.1 - 2.5e-05 24.4 65.1 8.6e-05 22.7 11.7 5.9 4 1 1 5 5 5 3 EGF domain EGF PF00008.27 KFP09478.1 - 0.0002 21.6 75.1 0.11 12.9 9.1 6.4 5 1 1 6 6 6 5 EGF-like domain EGF_2 PF07974.13 KFP09478.1 - 0.012 16.0 14.9 0.012 16.0 14.9 6.1 5 1 0 5 5 5 0 EGF-like domain EGF_MSP1_1 PF12946.7 KFP09478.1 - 0.042 13.9 39.5 0.088 12.9 7.2 4.7 4 0 0 4 4 4 0 MSP1 EGF domain 1 RabGAP-TBC PF00566.18 KFP09480.1 - 1e-42 146.2 0.1 1.6e-42 145.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KFP09480.1 - 2.1e-38 132.2 0.0 3.2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09480.1 - 2e-25 89.6 0.0 3.3e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 KFP09480.1 - 7.2e-14 52.2 0.0 1.4e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 KFP09480.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like tRNA_bind PF01588.20 KFP09481.1 - 3.6e-30 103.9 0.8 6e-30 103.2 0.1 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain SR-25 PF10500.9 KFP09481.1 - 0.0093 15.6 7.2 0.015 14.9 7.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NUDE_C PF04880.13 KFP09481.1 - 0.05 14.1 0.9 0.05 14.1 0.9 1.8 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Suf PF05843.14 KFP09481.1 - 0.23 11.4 1.5 0.28 11.1 1.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.19 KFP09481.1 - 0.43 11.2 8.2 1.2 9.7 8.2 1.9 1 1 0 1 1 1 0 60s Acidic ribosomal protein Coilin_N PF15862.5 KFP09481.1 - 0.74 9.6 7.7 1.4 8.7 7.7 1.4 1 0 0 1 1 1 0 Coilin N-terminus SlyX PF04102.12 KFP09481.1 - 1.9 9.2 5.0 15 6.3 5.0 2.4 1 1 0 1 1 1 0 SlyX YabA PF06156.13 KFP09481.1 - 3 8.5 8.2 13 6.4 8.2 2.0 1 1 0 1 1 1 0 Initiation control protein YabA RR_TM4-6 PF06459.12 KFP09481.1 - 5.6 6.7 11.4 7.7 6.2 11.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AIG1 PF04548.16 KFP09482.1 - 3.1e-25 88.7 0.0 4.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KFP09482.1 - 0.00082 19.4 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFP09482.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.18 KFP09482.1 - 0.039 13.3 0.1 0.072 12.4 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Prokineticin PF06607.11 KFP09483.1 - 0.0023 18.2 7.2 0.0028 17.9 7.2 1.1 1 0 0 1 1 1 1 Prokineticin Dickkopf_N PF04706.12 KFP09483.1 - 0.027 14.9 5.9 0.027 14.9 5.9 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Toxin_21 PF08091.11 KFP09483.1 - 3 7.9 12.4 0.075 13.0 4.7 2.2 2 1 0 2 2 2 0 Spider insecticidal peptide PDZ_6 PF17820.1 KFP09484.1 - 1.9e-09 37.2 0.2 4.1e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP09484.1 - 3e-07 30.7 0.0 1.2e-06 28.7 0.0 2.1 2 1 0 2 2 2 1 PDZ domain 2C_adapt PF08793.10 KFP09484.1 - 0.02 15.0 0.1 0.39 10.9 0.0 2.5 2 0 0 2 2 2 0 2-cysteine adaptor domain FERM_f0 PF16511.5 KFP09485.1 - 0.00023 21.4 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM Sulfatase PF00884.23 KFP09486.1 - 5.3e-13 49.0 0.0 5.7e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP09486.1 - 1.2e-06 28.3 0.0 1.2e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFP09486.1 - 0.0038 16.3 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Ras PF00071.22 KFP09487.1 - 1.2e-26 93.3 0.2 1.5e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09487.1 - 5.6e-20 71.7 0.1 1e-19 70.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09487.1 - 3.6e-06 26.6 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP09487.1 - 7e-05 22.5 0.0 0.00025 20.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP09487.1 - 0.0014 18.1 0.1 0.0027 17.1 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 KFP09487.1 - 0.0084 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KFP09487.1 - 0.031 14.1 0.1 0.041 13.7 0.1 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein NOG1 PF06858.14 KFP09487.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Laminin_G_2 PF02210.24 KFP09488.1 - 2.9e-21 76.3 0.2 2.5e-16 60.4 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP09488.1 - 2e-15 57.1 0.0 1.2e-11 44.9 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain DUF4154 PF13689.6 KFP09488.1 - 0.043 14.1 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 YfiR/HmsC-like F5_F8_type_C PF00754.25 KFP09489.1 - 1e-17 64.4 2.6 1.2e-17 64.3 2.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain Cadherin PF00028.17 KFP09490.1 - 7.7e-130 423.7 4.1 2.4e-21 76.0 0.0 8.1 7 1 1 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 KFP09490.1 - 1.4e-13 50.5 0.0 0.074 12.9 0.0 6.8 6 1 0 6 6 6 3 Cadherin-like Cadherin_3 PF16184.5 KFP09490.1 - 1.1e-12 47.9 6.2 0.0044 17.0 0.0 6.0 6 0 0 6 6 6 4 Cadherin-like Cadherin_pro PF08758.11 KFP09490.1 - 6.8e-06 26.2 0.0 1.2 9.3 0.0 4.1 4 0 0 4 4 4 2 Cadherin prodomain like Cadherin_4 PF17803.1 KFP09490.1 - 0.0033 18.0 20.7 0.01 16.5 0.5 6.0 6 0 0 6 6 6 1 Bacterial cadherin-like domain Big_9 PF17963.1 KFP09490.1 - 0.026 15.3 23.0 0.13 13.1 0.1 6.1 7 0 0 7 7 7 0 Bacterial Ig domain LRR_8 PF13855.6 KFP09491.1 - 2.7e-39 132.8 39.7 1.6e-15 56.6 8.3 7.6 5 2 2 7 7 7 7 Leucine rich repeat TIR PF01582.20 KFP09491.1 - 1.5e-21 77.0 0.6 2.4e-21 76.3 0.6 1.3 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFP09491.1 - 5.4e-20 71.2 47.5 0.00021 21.6 0.5 9.3 7 3 4 11 11 11 7 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KFP09491.1 - 2.3e-15 57.2 0.6 3.7e-14 53.3 0.2 2.8 3 0 0 3 3 3 1 TIR domain LRR_9 PF14580.6 KFP09491.1 - 1.8e-10 40.6 10.5 0.0019 17.7 1.3 4.9 2 2 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KFP09491.1 - 1e-07 31.5 35.4 0.0096 16.3 0.5 11.6 10 2 1 11 11 11 2 Leucine Rich Repeat DUF1863 PF08937.11 KFP09491.1 - 0.076 13.3 0.1 0.43 10.9 0.1 2.2 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_6 PF13516.6 KFP09491.1 - 0.16 12.1 30.9 9.9 6.5 0.1 10.2 11 0 0 11 11 11 0 Leucine Rich repeat TMEM131_like PF12371.8 KFP09492.1 - 1.3e-17 63.8 0.9 1.8e-16 60.2 0.3 3.0 3 0 0 3 3 3 1 Transmembrane protein 131-like ASH PF15780.5 KFP09492.1 - 1.4e-10 41.2 0.3 2.4e-06 27.7 0.0 4.8 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Ank_2 PF12796.7 KFP09493.1 - 2e-31 108.4 2.2 1.4e-15 57.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP09493.1 - 1.4e-30 104.4 5.3 2.8e-07 30.7 0.7 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFP09493.1 - 2.1e-30 104.7 5.2 5.5e-11 42.8 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP09493.1 - 2.3e-27 92.0 2.4 7.2e-06 26.0 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KFP09493.1 - 4.3e-25 87.5 5.6 7.6e-09 35.7 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 KFP09493.1 - 0.0066 16.4 0.2 0.33 11.0 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) CCDC144C PF14915.6 KFP09494.1 - 1.6e-127 424.8 64.5 1.6e-127 424.8 64.5 5.2 4 1 1 5 5 5 1 CCDC144C protein coiled-coil region DUF3496 PF12001.8 KFP09494.1 - 3.1e-20 72.6 0.8 3.1e-20 72.6 0.8 8.2 6 3 2 8 8 8 1 Domain of unknown function (DUF3496) DMPK_coil PF08826.10 KFP09494.1 - 0.0024 18.0 6.5 0.0024 18.0 6.5 12.5 7 4 7 14 14 14 1 DMPK coiled coil domain like HAP1_N PF04849.13 KFP09494.1 - 0.0029 16.8 22.1 0.0029 16.8 22.1 6.1 2 1 3 5 5 5 2 HAP1 N-terminal conserved region DUF4382 PF14321.6 KFP09494.1 - 1.4 9.2 11.8 0.073 13.3 0.5 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4382) COLFI PF01410.18 KFP09495.1 - 2.2e-58 197.3 0.0 2.4e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Abhydrolase_1 PF00561.20 KFP09496.1 - 7.8e-24 84.7 0.1 4.2e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP09496.1 - 8.3e-17 61.2 0.7 1.5e-15 57.1 0.7 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP09496.1 - 4.8e-15 56.8 0.1 9.6e-15 55.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFP09496.1 - 0.00022 21.1 0.3 0.52 10.1 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF2920 PF11144.8 KFP09496.1 - 0.0056 15.9 0.0 0.18 11.0 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) UBA_6 PF18039.1 KFP09496.1 - 0.011 15.7 0.2 0.038 13.9 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain FSH1 PF03959.13 KFP09496.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFP09496.1 - 0.024 14.1 0.1 0.19 11.2 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KFP09496.1 - 0.04 14.0 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 KFP09496.1 - 0.044 13.3 0.0 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 KFP09496.1 - 0.073 11.8 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.13 KFP09496.1 - 0.09 12.6 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.11 KFP09496.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal VirJ PF06057.11 KFP09496.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LIP PF03583.14 KFP09496.1 - 0.15 11.3 0.0 0.44 9.8 0.0 1.7 1 1 1 2 2 2 0 Secretory lipase Abhydrolase_8 PF06259.12 KFP09496.1 - 0.15 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DDA1 PF10172.9 KFP09497.1 - 1.8e-30 105.0 0.1 2.7e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Anoctamin PF04547.12 KFP09498.1 - 6.8e-53 180.1 2.1 2.9e-44 151.7 0.2 2.1 1 1 1 2 2 2 2 Calcium-activated chloride channel PX PF00787.24 KFP09499.1 - 1.8e-26 92.4 0.5 2.1e-26 92.1 0.5 1.1 1 0 0 1 1 1 1 PX domain PaO PF08417.12 KFP09499.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 Pheophorbide a oxygenase Chromo_shadow PF01393.19 KFP09500.1 - 7.9e-34 115.5 0.1 6.8e-31 106.1 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFP09500.1 - 7e-23 80.3 0.4 1.6e-18 66.3 0.4 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFP09500.1 - 0.0013 18.9 0.2 0.0094 16.1 0.2 2.0 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 CDC45 PF02724.14 KFP09500.1 - 0.81 7.9 5.6 0.87 7.8 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ELM2 PF01448.24 KFP09500.1 - 9.3 7.1 7.3 1.6 9.6 0.8 2.4 2 1 0 2 2 2 0 ELM2 domain Fn3-like PF14310.6 KFP09501.1 - 1.1e-16 60.7 1.5 1.6e-16 60.1 1.5 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain WD40 PF00400.32 KFP09502.1 - 4.5e-12 46.3 9.8 0.019 15.8 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09502.1 - 7.8e-07 29.3 0.1 0.45 10.9 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP09502.1 - 0.0044 15.8 0.0 0.16 10.7 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like SARS_X4 PF08779.10 KFP09502.1 - 0.17 12.1 0.2 0.84 9.9 0.1 2.1 2 0 0 2 2 2 0 SARS coronavirus X4 like RVT_1 PF00078.27 KFP09503.1 - 0.00023 20.7 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CLPTM1 PF05602.12 KFP09504.1 - 7.5e-145 483.2 2.3 8.6e-145 483.0 2.3 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KFP09504.1 - 0.015 15.1 2.5 0.49 10.2 0.2 2.7 2 0 0 2 2 2 0 PQ loop repeat Adaptin_N PF01602.20 KFP09505.1 - 5.3e-146 487.2 4.3 6.7e-146 486.9 4.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFP09505.1 - 2.4e-45 153.4 0.0 6.3e-45 152.0 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFP09505.1 - 5.4e-18 65.3 0.6 1.4e-17 64.0 0.6 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFP09505.1 - 3.8e-09 36.8 0.4 9.5e-07 29.0 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP09505.1 - 1e-05 25.8 3.9 0.009 16.4 0.1 4.7 3 1 2 5 5 5 1 HEAT repeats RIX1 PF08167.12 KFP09505.1 - 0.0011 18.8 3.1 0.11 12.3 0.2 3.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.10 KFP09505.1 - 0.021 14.6 1.5 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) IFRD PF05004.13 KFP09505.1 - 1.3 8.1 5.0 0.54 9.3 0.6 2.5 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Glyco_hydro_18 PF00704.28 KFP09506.1 - 3.2e-21 76.4 0.0 3.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 KFP09506.1 - 0.017 14.6 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Tetraspanin PF00335.20 KFP09507.1 - 7.2e-45 153.5 9.7 7.9e-45 153.3 9.7 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KFP09507.1 - 0.00025 21.1 5.8 0.00052 20.1 5.8 1.5 1 0 0 1 1 1 1 CD20-like family GP38 PF05268.11 KFP09507.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 DUF2207 PF09972.9 KFP09507.1 - 0.51 9.0 3.1 0.67 8.6 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MARVEL PF01284.23 KFP09507.1 - 4.5 7.3 12.8 1.4 8.9 9.3 1.8 2 0 0 2 2 2 0 Membrane-associating domain RNA_pol_N PF01194.17 KFP09508.1 - 1.3e-33 115.0 0.2 1.5e-33 114.9 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Tetraspanin PF00335.20 KFP09509.1 - 4.8e-44 150.8 19.8 1.8e-35 122.7 7.4 2.0 1 1 1 2 2 2 2 Tetraspanin family EI24 PF07264.11 KFP09509.1 - 0.00062 20.1 0.4 0.00095 19.4 0.4 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4834 PF16118.5 KFP09509.1 - 0.21 12.5 0.0 0.21 12.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4500 PF14937.6 KFP09509.1 - 0.31 11.1 3.0 13 5.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF2207 PF09972.9 KFP09509.1 - 1.3 7.8 3.3 1 8.0 1.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Deltameth_res PF16020.5 KFP09509.1 - 1.4 8.9 4.6 0.89 9.5 0.4 2.6 2 0 0 2 2 2 0 Deltamethrin resistance DUF1951 PF09188.10 KFP09509.1 - 4.8 7.2 6.7 2.4 8.2 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1951) Ras PF00071.22 KFP09510.1 - 4.5e-51 172.7 0.2 4.9e-51 172.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09510.1 - 2.2e-31 108.6 0.1 2.9e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09510.1 - 3.8e-15 55.8 0.0 4.3e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP09510.1 - 6.3e-09 35.5 0.0 7.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP09510.1 - 1.7e-08 34.5 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP09510.1 - 1.9e-08 34.1 0.0 7e-08 32.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP09510.1 - 8.9e-05 22.5 0.0 0.0052 16.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFP09510.1 - 0.014 15.5 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family CENP-M PF11111.8 KFP09510.1 - 0.037 13.2 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) SRPRB PF09439.10 KFP09510.1 - 0.037 13.4 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFP09510.1 - 0.045 13.0 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_33 PF13671.6 KFP09510.1 - 0.045 13.9 0.0 0.064 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP09510.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFP09510.1 - 0.09 12.5 0.1 0.53 10.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain EF-hand_7 PF13499.6 KFP09511.1 - 2.2e-08 34.4 0.3 5.1e-06 26.8 0.2 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP09511.1 - 1e-06 28.2 0.1 0.01 15.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP09511.1 - 4.4e-06 25.9 0.6 0.032 13.8 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFP09511.1 - 0.0041 17.0 0.0 0.021 14.7 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair TMEM215 PF15746.5 KFP09511.1 - 0.38 10.2 2.1 0.46 9.9 1.3 1.5 1 1 0 1 1 1 0 TMEM215 family Peptidase_S46 PF10459.9 KFP09511.1 - 5.6 5.5 18.0 8.5 4.9 18.0 1.3 1 0 0 1 1 1 0 Peptidase S46 Ribosomal_60s PF00428.19 KFP09512.1 - 8.2e-26 90.4 7.8 1.1e-25 90.0 7.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KFP09512.1 - 0.015 15.6 0.6 0.017 15.5 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain TFIID_30kDa PF03540.13 KFP09512.1 - 0.092 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit LRR_8 PF13855.6 KFP09513.1 - 6.2e-20 70.7 32.8 2.2e-09 37.0 8.1 5.4 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KFP09513.1 - 2.2e-18 66.1 28.6 2.9e-06 27.5 2.7 6.6 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) Peptidase_S68 PF10461.9 KFP09513.1 - 5.2e-18 64.9 13.9 9e-17 61.0 7.1 2.7 2 0 0 2 2 2 2 Peptidase S68 ZU5 PF00791.20 KFP09513.1 - 6.3e-18 64.9 0.4 8.6e-15 54.9 0.0 2.5 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 KFP09513.1 - 2.1e-11 43.8 0.1 6.9e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 Death domain LRR_1 PF00560.33 KFP09513.1 - 1.2 9.9 33.1 2.7 8.9 2.2 8.0 7 2 0 7 7 7 0 Leucine Rich Repeat Mito_carr PF00153.27 KFP09514.1 - 1.4e-64 214.0 1.6 5.5e-24 83.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COR PF16095.5 KFP09515.1 - 6e-05 22.9 0.1 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain DUF3418 PF11898.8 KFP09515.1 - 0.056 12.1 0.2 0.067 11.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) PHD PF00628.29 KFP09516.1 - 4.2e-14 52.2 3.6 9.9e-14 51.0 3.6 1.7 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KFP09516.1 - 0.044 14.1 1.9 0.11 12.8 1.9 1.7 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 KFP09516.1 - 0.065 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFP09516.1 - 0.071 13.1 2.1 0.19 11.7 2.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KFP09516.1 - 0.074 12.6 0.4 0.15 11.7 0.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KFP09516.1 - 0.31 11.4 4.8 0.89 9.9 4.8 1.9 1 0 0 1 1 1 0 Ring finger domain LRR_4 PF12799.7 KFP09517.1 - 2.3e-10 40.5 5.3 4.6e-05 23.7 0.1 3.2 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP09517.1 - 2.5e-10 40.0 9.5 3e-06 26.9 0.9 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KFP09517.1 - 9.1e-06 25.3 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KFP09517.1 - 4.6e-05 23.1 11.9 0.097 12.8 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFP09517.1 - 0.16 12.6 10.9 2.9 8.8 1.2 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat MACPF PF01823.19 KFP09518.1 - 5.2e-07 30.0 0.1 2.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 MAC/Perforin domain adh_short_C2 PF13561.6 KFP09519.1 - 2.5e-45 154.8 0.0 3.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP09519.1 - 8.7e-32 110.2 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP09519.1 - 0.0086 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 KR domain EF_assoc_2 PF08356.12 KFP09520.1 - 1.5e-36 124.3 0.0 3.8e-36 122.9 0.0 1.8 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KFP09520.1 - 1.1e-24 85.8 0.5 8.5e-24 83.0 0.0 2.3 2 1 0 2 2 2 1 EF hand associated Ras PF00071.22 KFP09520.1 - 6.5e-20 71.4 0.0 1.1e-13 51.1 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KFP09520.1 - 4.6e-07 30.1 0.0 0.0032 17.7 0.0 3.6 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 KFP09520.1 - 1.3e-06 28.7 0.0 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP09520.1 - 1.6e-06 27.6 0.8 0.0002 21.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP09520.1 - 2.8e-06 26.5 0.5 0.0019 17.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP09520.1 - 0.0011 18.4 0.1 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 EF hand Dynamin_N PF00350.23 KFP09520.1 - 0.0039 17.3 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFP09520.1 - 0.009 16.1 0.0 5.6 7.1 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase SPARC_Ca_bdg PF10591.9 KFP09520.1 - 0.056 13.8 0.1 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFP09520.1 - 0.077 12.9 1.3 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KFP09520.1 - 0.14 12.0 0.1 23 5.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair U-box PF04564.15 KFP09521.1 - 3.4e-31 107.2 0.0 5.4e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 KFP09521.1 - 5.2e-17 62.4 13.2 7.8e-17 61.8 9.1 2.7 2 1 0 2 2 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 KFP09521.1 - 8.5e-16 57.0 6.9 8.1e-10 38.1 0.8 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP09521.1 - 2e-12 46.2 6.0 9.8e-06 25.3 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP09521.1 - 4.1e-11 42.9 1.6 8.4e-11 42.0 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP09521.1 - 7.5e-11 42.2 11.1 1.5e-08 34.8 4.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP09521.1 - 4.8e-10 38.8 4.1 0.00023 21.1 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP09521.1 - 2.4e-07 31.1 2.9 4.2e-07 30.4 2.9 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP09521.1 - 1.8e-06 27.5 0.6 0.0068 16.1 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.6 KFP09521.1 - 2.2e-05 24.5 0.5 3.8e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP09521.1 - 2.2e-05 25.0 0.2 3.7e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP09521.1 - 4.1e-05 23.7 0.9 0.36 11.3 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP09521.1 - 5.5e-05 22.9 3.4 0.13 12.3 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP09521.1 - 0.00023 21.6 2.7 0.59 10.9 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP09521.1 - 0.00026 21.6 0.3 0.015 16.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP09521.1 - 0.0053 16.2 1.2 0.042 13.3 0.1 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_10 PF13374.6 KFP09521.1 - 0.009 15.9 3.3 0.43 10.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP09521.1 - 0.025 13.8 0.2 0.052 12.8 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 KFP09521.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein WD40 PF00400.32 KFP09522.1 - 2.9e-07 31.1 0.6 0.27 12.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09522.1 - 0.0053 17.0 0.0 1.3 9.3 0.0 3.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LRR_6 PF13516.6 KFP09523.1 - 8.1e-12 44.2 11.0 0.066 13.3 0.0 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KFP09523.1 - 1.1e-08 35.2 2.4 0.058 13.8 0.1 4.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP09523.1 - 0.00014 21.6 3.7 1.4 8.7 0.4 4.6 4 1 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.7 KFP09523.1 - 0.0042 16.9 1.0 0.014 15.3 1.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFP09523.1 - 0.0078 16.6 14.4 0.45 11.3 0.0 6.5 7 1 0 7 7 7 2 Leucine Rich Repeat F-box PF00646.33 KFP09523.1 - 0.033 14.1 0.1 0.033 14.1 0.1 2.8 3 0 0 3 3 3 0 F-box domain DIRP PF06584.13 KFP09524.1 - 0.019 15.1 0.4 0.11 12.7 0.5 2.3 2 0 0 2 2 1 0 DIRP OmpH PF03938.14 KFP09524.1 - 0.061 13.7 21.6 0.04 14.2 9.7 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Hemerythrin PF01814.23 KFP09524.1 - 0.19 12.3 4.7 1.9 9.1 0.3 3.4 2 2 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF4635 PF15466.6 KFP09524.1 - 0.28 10.7 8.3 0.099 12.2 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) DLP_helical PF18709.1 KFP09524.1 - 0.55 9.4 7.7 0.048 12.9 2.4 2.0 2 1 0 2 2 2 0 Dynamin-like helical domain PhoU PF01895.19 KFP09524.1 - 0.81 10.2 0.0 0.81 10.2 0.0 3.0 3 1 0 3 3 3 0 PhoU domain Ribosomal_S20p PF01649.18 KFP09524.1 - 1.2 9.9 10.2 2.3 8.9 0.4 4.0 3 1 1 4 4 4 0 Ribosomal protein S20 DUF1664 PF07889.12 KFP09524.1 - 1.7 8.7 12.1 0.15 12.1 3.9 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) SPX PF03105.19 KFP09524.1 - 5.4 6.8 9.2 3.1 7.6 5.9 1.9 1 1 1 2 2 2 0 SPX domain RBD-FIP PF09457.10 KFP09524.1 - 6.3 6.8 8.2 1.1 9.2 0.3 3.2 2 1 0 2 2 2 0 FIP domain FUSC PF04632.12 KFP09524.1 - 6.6 5.1 7.8 1.1 7.6 0.3 2.3 2 1 0 2 2 2 0 Fusaric acid resistance protein family ParA PF10609.9 KFP09525.1 - 8.3e-99 330.0 0.0 9.4e-99 329.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFP09525.1 - 3.5e-12 46.5 0.0 4.6e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFP09525.1 - 4.6e-08 33.2 0.2 4.3e-07 30.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KFP09525.1 - 6.2e-08 32.2 0.0 2.3e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFP09525.1 - 1.1e-06 28.1 0.9 6.8e-06 25.5 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 KFP09525.1 - 2.9e-06 27.2 0.0 2.8e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KFP09525.1 - 5.4e-05 22.3 0.1 7.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 KFP09525.1 - 0.00016 21.2 0.0 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KFP09525.1 - 0.0013 18.3 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KFP09525.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFP09525.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 KFP09525.1 - 0.028 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 KFP09525.1 - 0.029 14.0 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFP09525.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CLP1_P PF16575.5 KFP09525.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KFP09525.1 - 0.09 11.9 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KFP09525.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP09525.1 - 0.16 12.4 0.4 0.32 11.4 0.4 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KFP09525.1 - 0.24 11.3 0.2 0.45 10.4 0.2 1.4 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 KFP09525.1 - 0.25 11.2 0.6 0.64 9.9 0.6 1.6 1 0 0 1 1 1 0 RsgA GTPase SPRY PF00622.28 KFP09526.1 - 2.2e-19 69.7 0.3 5e-19 68.6 0.1 1.6 2 0 0 2 2 2 1 SPRY domain SOCS_box PF07525.16 KFP09526.1 - 0.00036 20.8 1.9 0.00073 19.9 1.9 1.5 1 0 0 1 1 1 1 SOCS box ERCC4 PF02732.15 KFP09527.1 - 7.4e-09 36.0 0.0 2.5e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 ERCC4 domain Catalase-rel PF06628.12 KFP09527.1 - 0.072 13.3 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Catalase-related immune-responsive NDK PF00334.19 KFP09528.1 - 1.3e-55 187.1 0.0 1.5e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 KFP09528.1 - 0.023 15.2 0.0 0.039 14.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ UBN_AB PF14075.6 KFP09529.1 - 1.9e-83 279.4 2.4 1.9e-83 279.4 2.4 3.2 2 1 1 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 KFP09529.1 - 1.4e-19 69.8 0.7 1.4e-19 69.8 0.7 2.3 3 0 0 3 3 3 1 HPC2 and ubinuclein domain CpxA_peri PF16527.5 KFP09529.1 - 1.2 9.6 3.6 24 5.3 2.0 2.7 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Cellulose_synt PF03552.14 KFP09529.1 - 3.3 6.1 3.5 5.4 5.4 3.5 1.2 1 0 0 1 1 1 0 Cellulose synthase SH3_10 PF17902.1 KFP09530.1 - 2.2e-07 30.9 0.0 1.2e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 SH3 domain Plectin PF00681.20 KFP09530.1 - 0.0013 18.6 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 2 Plectin repeat Spectrin PF00435.21 KFP09530.1 - 1.1 9.8 0.0 0.076 13.5 3.5 17.2 10 3 9 19 19 19 0 Spectrin repeat PDZ PF00595.24 KFP09531.1 - 1e-10 41.8 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain TPR_MLP1_2 PF07926.12 KFP09531.1 - 0.00087 19.4 8.5 0.00087 19.4 8.5 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 KFP09531.1 - 0.0051 16.6 5.9 0.61 10.0 0.8 3.2 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase PDZ_6 PF17820.1 KFP09531.1 - 0.0081 16.0 0.1 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain DUF4763 PF15960.5 KFP09531.1 - 0.013 14.8 7.4 0.013 14.8 7.4 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4763) Laminin_II PF06009.12 KFP09531.1 - 0.014 15.5 9.9 0.021 14.8 9.3 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF2730 PF10805.8 KFP09531.1 - 0.022 14.8 5.1 0.18 11.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF1192 PF06698.11 KFP09531.1 - 0.091 12.8 9.2 0.12 12.5 1.1 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) FAP206 PF12018.8 KFP09531.1 - 0.2 11.2 7.3 0.082 12.4 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function CCDC74_C PF14917.6 KFP09531.1 - 0.47 11.0 7.7 0.51 10.9 6.3 1.8 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal GAS PF13851.6 KFP09531.1 - 1.1 8.6 23.8 0.67 9.3 6.4 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 KFP09531.1 - 1.1 8.0 3.7 1.7 7.5 3.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KFP09531.1 - 1.4 9.5 27.3 0.059 13.9 13.1 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 KFP09531.1 - 1.9 8.7 12.8 0.88 9.7 5.0 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 KFP09531.1 - 2.2 7.3 12.2 4 6.4 12.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 KFP09531.1 - 2.3 8.5 11.4 5.1 7.4 11.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 KFP09531.1 - 3.1 7.9 19.2 10 6.2 18.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KFP09531.1 - 3.2 7.0 7.6 7.5 5.8 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Noelin-1 PF12308.8 KFP09531.1 - 4.9 7.2 6.9 1.6 8.8 2.1 2.2 1 1 2 3 3 3 0 Neurogenesis glycoprotein RRP36 PF06102.12 KFP09531.1 - 5.6 6.9 16.9 1.1 9.2 6.6 2.5 1 1 1 2 2 2 0 rRNA biogenesis protein RRP36 PRELI PF04707.14 KFP09532.1 - 2.3e-47 160.7 0.5 3.6e-47 160.1 0.5 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 KFP09532.1 - 1.2e-42 145.4 0.0 3.2e-42 144.0 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP09532.1 - 2.1e-07 31.0 0.1 5.4e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NAGPA PF09992.9 KFP09533.1 - 9.3e-39 133.3 0.2 1.2e-38 133.0 0.2 1.1 1 0 0 1 1 1 1 Phosphodiester glycosidase EGF_2 PF07974.13 KFP09533.1 - 0.0082 16.5 12.7 0.0082 16.5 12.7 4.9 5 0 0 5 5 5 3 EGF-like domain EGF_Tenascin PF18720.1 KFP09533.1 - 0.024 14.7 11.2 0.024 14.7 11.2 3.8 4 0 0 4 4 4 0 Tenascin EGF domain Glycos_transf_1 PF00534.20 KFP09534.1 - 3.1e-08 33.3 0.0 4.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP09534.1 - 5e-06 27.0 0.0 7.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFP09534.1 - 5.5e-05 23.2 0.1 9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KFP09534.1 - 0.0018 18.8 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFP09534.1 - 0.026 14.9 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_16 PF10294.9 KFP09535.1 - 3.5e-17 62.7 0.0 3e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Met_10 PF02475.16 KFP09535.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_12 PF08242.12 KFP09535.1 - 0.039 14.7 0.0 0.1 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFP09535.1 - 0.084 13.6 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFP09535.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Gpi1 PF05024.15 KFP09537.1 - 1.7e-65 220.6 10.5 3.9e-65 219.5 10.5 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.22 KFP09538.1 - 1e-33 116.3 0.0 1.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09538.1 - 5.8e-14 52.3 0.0 8.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 KFP09538.1 - 1.4e-07 31.7 0.4 2.7e-07 30.8 0.4 1.5 1 0 0 1 1 1 1 SOCS box Arf PF00025.21 KFP09538.1 - 0.0096 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC2_membrane_3 PF12698.7 KFP09539.1 - 7.3e-57 193.0 50.3 2.8e-34 118.7 22.6 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFP09539.1 - 1.7e-50 171.1 0.0 1.8e-25 90.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFP09539.1 - 7.2e-21 75.3 0.2 1.6e-07 31.5 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP09539.1 - 0.00026 20.9 1.0 0.0054 16.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KFP09539.1 - 0.00069 20.2 4.1 0.038 14.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain DUF4162 PF13732.6 KFP09539.1 - 0.0014 19.3 0.0 0.26 12.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 KFP09539.1 - 0.0015 18.0 0.1 1.3 8.4 0.0 3.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFP09539.1 - 0.0099 15.6 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP09539.1 - 0.011 16.0 1.0 1.3 9.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KFP09539.1 - 0.019 15.1 0.2 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 KFP09539.1 - 0.025 14.3 0.0 0.28 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.6 KFP09539.1 - 0.033 14.4 0.0 1.1 9.6 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFP09539.1 - 0.036 13.8 2.3 0.33 10.7 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arf PF00025.21 KFP09539.1 - 0.065 12.7 0.5 12 5.3 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 KFP09539.1 - 0.087 12.5 1.1 25 4.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KFP09539.1 - 0.096 13.1 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KFP09539.1 - 0.11 12.1 4.8 1 9.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KFP09539.1 - 0.19 11.6 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_13 PF13166.6 KFP09539.1 - 0.27 9.8 0.4 6.1 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFP09539.1 - 1.1 8.8 2.9 15 5.1 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 KFP09540.1 - 7.8e-08 32.0 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09540.1 - 4.6e-06 26.1 0.0 5.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP09540.1 - 8.2e-06 24.8 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase m04gp34like PF12216.8 KFP09540.1 - 0.18 11.4 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Immune evasion protein Cyclin_N PF00134.23 KFP09541.1 - 9.8e-28 96.4 3.6 3.2e-27 94.8 0.4 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP09541.1 - 1.3e-17 64.0 0.5 3.2e-17 62.7 0.5 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4693 PF15764.5 KFP09542.1 - 6.5e-95 318.0 6.6 7.8e-95 317.7 6.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) K_channel_TID PF07941.11 KFP09542.1 - 0.83 10.1 3.0 1.7 9.1 3.0 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain NKAIN PF05640.14 KFP09545.1 - 2.4e-24 85.7 4.1 2.5e-24 85.7 4.1 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF4462 PF14692.6 KFP09547.1 - 0.37 10.3 1.1 0.51 9.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Asp_Arg_Hydrox PF05118.15 KFP09549.1 - 8.8e-57 191.3 0.4 2e-56 190.2 0.4 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Asp-B-Hydro_N PF05279.11 KFP09549.1 - 2.7e-51 175.0 2.2 5.6e-51 174.0 0.4 2.0 1 1 1 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region TPR_14 PF13428.6 KFP09549.1 - 6.4e-08 32.8 0.0 0.004 17.8 0.2 4.6 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP09549.1 - 6.5e-08 32.1 8.1 0.032 14.3 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP09549.1 - 7.4e-08 32.0 2.8 0.046 14.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP09549.1 - 7.6e-08 32.5 3.8 0.025 15.2 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP09549.1 - 3e-07 31.0 0.4 0.0003 21.4 0.5 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP09549.1 - 2e-05 24.8 0.1 0.4 11.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP09549.1 - 3.4e-05 23.5 4.4 0.22 11.4 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP09549.1 - 5.3e-05 23.7 0.1 0.064 13.8 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP09549.1 - 0.00049 19.7 4.6 0.19 11.5 0.1 4.8 5 0 0 5 5 5 1 TPR repeat PDR_CDR PF06422.12 KFP09549.1 - 0.0051 16.7 0.8 0.013 15.4 0.8 1.6 1 0 0 1 1 1 1 CDR ABC transporter YfiO PF13525.6 KFP09549.1 - 0.021 14.5 0.4 0.14 11.9 0.3 2.3 2 1 0 2 2 2 0 Outer membrane lipoprotein ATG27 PF09451.10 KFP09549.1 - 0.031 14.1 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 CTNNBL PF08216.11 KFP09549.1 - 0.031 14.4 1.2 0.093 12.9 1.2 1.8 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear LUC7 PF03194.15 KFP09549.1 - 0.082 12.6 0.7 0.14 11.8 0.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus TPR_7 PF13176.6 KFP09549.1 - 0.088 12.9 0.7 22 5.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CRAL_TRIO PF00650.20 KFP09550.1 - 3.7e-34 117.7 0.0 5.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP09550.1 - 3e-08 33.9 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP09550.1 - 1.4e-06 28.4 0.1 2.7e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNF2_N PF00176.23 KFP09551.1 - 6.3e-63 212.6 0.3 1.1e-62 211.8 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain BRK PF07533.16 KFP09551.1 - 1.8e-37 126.7 2.8 1.9e-18 65.8 0.2 2.5 2 0 0 2 2 2 2 BRK domain Chromo PF00385.24 KFP09551.1 - 1e-24 86.2 9.1 4.5e-13 48.9 0.5 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KFP09551.1 - 6.6e-17 61.9 0.0 1.7e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP09551.1 - 6.9e-07 29.4 0.0 2.3e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFP09551.1 - 6.5e-05 23.2 4.0 1.2 9.3 0.0 4.6 4 0 0 4 4 4 2 CHDCT2 (NUC038) domain Myb_DNA-bind_7 PF15963.5 KFP09551.1 - 0.014 15.3 0.2 0.088 12.7 0.2 2.4 1 0 0 1 1 1 0 Myb DNA-binding like DUF3439 PF11921.8 KFP09551.1 - 0.68 9.9 5.1 1.7 8.6 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ras PF00071.22 KFP09552.1 - 9.5e-57 191.1 0.0 1.1e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09552.1 - 1e-29 103.2 0.0 1.6e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09552.1 - 7.5e-12 45.0 0.0 8.4e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP09552.1 - 0.00074 19.1 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP09552.1 - 0.0024 17.3 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP09552.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP09552.1 - 0.052 13.5 0.0 1.3 8.9 0.0 2.3 1 1 0 2 2 2 0 RsgA GTPase Carb_anhydrase PF00194.21 KFP09554.1 - 3.1e-79 266.1 0.0 3.4e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HMG_box PF00505.19 KFP09556.1 - 9.4e-18 64.4 0.4 2e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP09556.1 - 8.1e-12 45.6 0.6 1.7e-11 44.5 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KFP09556.1 - 0.021 15.4 1.7 0.029 15.0 0.6 2.0 1 1 1 2 2 2 0 YABBY protein Mitofilin PF09731.9 KFP09556.1 - 0.12 11.2 5.8 0.16 10.8 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PDZ_6 PF17820.1 KFP09558.1 - 6e-23 80.5 0.4 3e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFP09558.1 - 4e-21 75.2 2.2 4.3e-13 49.4 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP09558.1 - 2.4e-12 47.0 0.2 2.2e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain p450 PF00067.22 KFP09559.1 - 2.9e-78 263.7 0.7 3.6e-78 263.4 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAM110_N PF14161.6 KFP09561.1 - 2.7e-44 149.7 3.8 6.8e-44 148.5 3.8 1.7 1 0 0 1 1 1 1 Centrosome-associated N terminus FAM110_C PF14160.6 KFP09561.1 - 2.3e-33 115.6 0.3 2.3e-33 115.6 0.3 2.0 2 0 0 2 2 2 1 Centrosome-associated C terminus Inositol_P PF00459.25 KFP09564.1 - 3.7e-35 121.7 0.4 4.3e-35 121.6 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RuvA_N PF01330.21 KFP09564.1 - 0.024 14.7 0.1 0.051 13.7 0.1 1.5 1 0 0 1 1 1 0 RuvA N terminal domain Opiods_neuropep PF01160.18 KFP09566.1 - 1.7e-07 31.2 2.6 2.5e-07 30.7 2.6 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide Op_neuropeptide PF08035.11 KFP09566.1 - 0.0017 18.2 40.5 0.61 10.0 0.2 7.2 7 0 0 7 7 7 6 Opioids neuropeptide SRF-TF PF00319.18 KFP09566.1 - 0.086 12.3 5.8 1.4 8.4 0.3 3.2 4 0 0 4 4 4 0 SRF-type transcription factor (DNA-binding and dimerisation domain) adh_short PF00106.25 KFP09567.1 - 1e-48 165.4 0.1 1.1e-48 165.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP09567.1 - 1.1e-32 113.5 0.1 1.3e-32 113.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP09567.1 - 2.6e-10 40.5 0.1 3.4e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KFP09567.1 - 0.0063 17.2 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 KFP09567.1 - 0.07 12.5 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KFP09567.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiX PF01903.17 KFP09567.1 - 0.14 12.5 0.0 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 CbiX MTCP1 PF08991.10 KFP09568.1 - 0.0013 19.0 0.4 0.0015 18.7 0.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CEP1-DNA_bind PF09287.10 KFP09568.1 - 0.0025 17.5 0.2 0.003 17.2 0.2 1.1 1 0 0 1 1 1 1 CEP-1, DNA binding CHCH PF06747.13 KFP09568.1 - 0.38 11.0 4.5 0.56 10.4 4.5 1.3 1 0 0 1 1 1 0 CHCH domain zf-H2C2_2 PF13465.6 KFP09569.1 - 2.7e-25 87.6 56.2 3.7e-05 23.9 1.0 8.5 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP09569.1 - 2e-24 84.1 58.0 0.00058 20.5 1.1 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP09569.1 - 5.4e-23 80.1 64.8 6.1e-05 23.3 1.4 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP09569.1 - 1.6e-05 24.7 51.8 0.023 14.7 0.6 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP09569.1 - 2.3e-05 24.6 45.1 0.032 14.5 1.1 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP09569.1 - 0.00027 21.2 26.9 0.29 11.6 0.7 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP09569.1 - 0.0021 18.3 30.4 0.038 14.3 10.3 4.3 1 1 2 3 3 3 2 C2H2-type zinc ribbon Acyltransf_C PF16076.5 KFP09569.1 - 0.0052 16.8 3.8 0.92 9.6 0.7 2.7 2 0 0 2 2 2 2 Acyltransferase C-terminus zf-C2H2_11 PF16622.5 KFP09569.1 - 0.035 13.9 0.0 0.035 13.9 0.0 6.6 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP09569.1 - 0.1 13.0 40.8 1.1 9.6 1.4 5.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFP09569.1 - 2 8.3 8.7 1.2e+02 2.6 0.0 5.1 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-LITAF-like PF10601.9 KFP09569.1 - 7.3 6.9 14.9 0.25 11.6 2.4 3.7 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain zf-Di19 PF05605.12 KFP09569.1 - 9.3 6.6 37.2 0.8 10.0 1.1 5.0 1 1 6 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 KFP09570.1 - 2.4e-45 155.0 0.0 3.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09570.1 - 3.8e-40 137.8 0.0 4.6e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP09570.1 - 0.0029 17.0 0.0 0.0088 15.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP09570.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_S10 PF00338.22 KFP09571.1 - 4.7e-31 106.9 0.3 5.6e-31 106.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase_Tyr PF07714.17 KFP09572.1 - 2.3e-96 322.0 0.0 3e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP09572.1 - 2.8e-48 164.6 0.0 4e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP09572.1 - 4.1e-23 81.3 0.0 8.6e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP09572.1 - 1.6e-16 59.6 0.1 3.7e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP09572.1 - 3.4e-08 33.0 0.5 1.2e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFP09572.1 - 1e-07 31.7 0.0 2.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP09572.1 - 0.0042 17.3 0.1 0.0088 16.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFP09572.1 - 0.02 13.9 0.1 0.042 12.8 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DUF2070 PF09843.9 KFP09572.1 - 0.12 10.7 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ras PF00071.22 KFP09573.1 - 2.8e-45 153.8 0.3 3.2e-45 153.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09573.1 - 4e-22 78.7 0.1 7.1e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09573.1 - 2.6e-11 43.3 0.3 3.2e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP09573.1 - 2e-05 24.2 0.0 3.8e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP09573.1 - 0.0042 16.5 0.2 0.0045 16.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Y_phosphatase PF00102.27 KFP09574.1 - 1.2e-150 499.6 0.1 7.2e-84 281.0 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP09574.1 - 1.2e-24 86.4 14.0 3.8e-10 40.0 0.0 5.7 6 0 0 6 6 5 3 Fibronectin type III domain MAM PF00629.23 KFP09574.1 - 2e-22 79.8 0.0 5.8e-22 78.3 0.0 1.9 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu ig PF00047.25 KFP09574.1 - 4.5e-09 36.4 0.0 1.2e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain DSPc PF00782.20 KFP09574.1 - 1.1e-08 34.9 0.1 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ig_3 PF13927.6 KFP09574.1 - 2.6e-05 24.7 0.0 0.00013 22.5 0.0 2.2 2 0 0 2 2 1 1 Immunoglobulin domain Y_phosphatase3 PF13350.6 KFP09574.1 - 5.2e-05 23.3 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP09574.1 - 0.00015 21.9 0.0 0.083 13.0 0.0 2.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 KFP09574.1 - 0.00034 21.1 1.6 0.43 11.2 0.1 3.9 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain I-set PF07679.16 KFP09574.1 - 0.00037 20.5 0.0 0.00094 19.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP09574.1 - 0.00096 19.4 0.0 0.0054 17.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ECSCR PF15820.5 KFP09574.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 KFP09574.1 - 0.038 14.9 0.3 0.17 12.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF948 PF06103.11 KFP09574.1 - 0.11 12.7 0.4 0.35 11.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DctM PF06808.12 KFP09574.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component LRR_8 PF13855.6 KFP09577.1 - 1.7e-24 85.3 25.7 2.8e-10 39.8 6.5 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP09577.1 - 2.1e-19 69.3 47.2 7.6e-07 29.4 4.2 5.7 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP09577.1 - 8.1e-08 31.8 32.0 0.54 11.0 0.2 9.1 8 2 0 8 8 8 4 Leucine Rich Repeat LRR_9 PF14580.6 KFP09577.1 - 2.7e-06 27.0 10.6 0.0049 16.4 2.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFP09577.1 - 0.071 13.1 1.1 0.11 12.5 1.1 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) USP7_C2 PF14533.6 KFP09577.1 - 0.097 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal LRR_6 PF13516.6 KFP09577.1 - 6.6 7.1 30.4 0.41 10.8 0.4 7.4 9 0 0 9 9 9 0 Leucine Rich repeat RVT_1 PF00078.27 KFP09580.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AKAP7_NLS PF10469.9 KFP09582.1 - 3.2e-43 148.1 0.4 3.6e-43 147.9 0.4 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KFP09582.1 - 4.1e-07 30.0 0.0 5.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFP09582.1 - 0.0018 18.5 0.1 0.079 13.2 0.0 2.5 2 1 0 2 2 2 1 LigT like Phosphoesterase Sugar-bind PF04198.13 KFP09582.1 - 0.061 12.5 0.1 0.085 12.0 0.1 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain FCD PF07729.12 KFP09582.1 - 0.068 13.6 0.0 0.51 10.8 0.0 2.1 2 1 0 2 2 2 0 FCD domain 4_1_CTD PF05902.13 KFP09584.1 - 8.9e-52 173.7 15.2 8.9e-52 173.7 15.2 3.2 4 0 0 4 4 4 1 4.1 protein C-terminal domain (CTD) SAB PF04382.13 KFP09584.1 - 2.2e-25 88.5 2.5 7.5e-25 86.8 2.5 2.0 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.10 KFP09584.1 - 7.3e-24 84.0 0.0 1.7e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP09584.1 - 5.8e-21 74.2 0.1 3.5e-20 71.7 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KFP09584.1 - 3.1e-19 69.5 0.0 3.1e-19 69.5 0.0 3.2 2 1 0 3 3 3 1 FERM central domain FA PF08736.11 KFP09584.1 - 7e-19 67.6 4.3 2.2e-18 66.0 4.3 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) RNA_pol_Rpc4 PF05132.14 KFP09584.1 - 0.21 12.0 0.0 0.21 12.0 0.0 5.9 5 2 1 6 6 6 0 RNA polymerase III RPC4 BTB PF00651.31 KFP09585.1 - 2.9e-28 98.3 0.8 5.2e-28 97.5 0.8 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP09585.1 - 1.7e-25 88.0 32.5 2.1e-05 24.7 0.2 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP09585.1 - 1.8e-23 81.8 47.2 9.3e-07 29.0 2.6 6.5 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP09585.1 - 2.1e-15 56.1 37.8 0.0043 17.8 1.1 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP09585.1 - 2.8e-13 49.8 21.2 0.0051 17.2 0.6 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP09585.1 - 3e-13 49.7 23.8 0.0063 16.8 0.2 5.8 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFP09585.1 - 0.012 16.0 36.5 1.4 9.4 6.1 6.5 3 3 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 KFP09585.1 - 0.014 15.0 15.2 0.59 9.8 0.2 5.1 3 2 2 5 5 5 0 MYST family zinc finger domain LIM PF00412.22 KFP09585.1 - 0.048 13.9 21.5 0.44 10.8 0.4 4.5 2 2 2 4 4 4 0 LIM domain zf-C2HC_2 PF13913.6 KFP09585.1 - 0.076 12.9 5.6 1.6 8.7 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type BTB_2 PF02214.22 KFP09585.1 - 0.088 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 BTB/POZ domain zf-C2H2_3rep PF18868.1 KFP09585.1 - 0.098 13.3 13.9 3.4 8.4 2.9 4.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KFP09585.1 - 0.13 11.8 15.5 1.5 8.5 0.2 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFP09585.1 - 0.19 11.5 9.6 8.8 6.2 0.0 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type C1_4 PF07975.12 KFP09585.1 - 0.33 11.2 16.0 5.5 7.3 1.7 4.1 1 1 1 3 3 3 0 TFIIH C1-like domain zf-Di19 PF05605.12 KFP09585.1 - 0.68 10.3 23.2 0.42 11.0 3.2 3.3 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Yippee-Mis18 PF03226.14 KFP09585.1 - 1.7 8.9 10.9 4.6 7.5 1.7 3.6 4 0 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_15 PF17032.5 KFP09585.1 - 3.2 8.6 16.9 5.6 7.8 2.1 3.7 2 1 2 4 4 3 0 zinc-ribbon family ADK_lid PF05191.14 KFP09585.1 - 4.2 7.4 6.7 7.4 6.7 2.2 3.0 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-CRD PF17979.1 KFP09585.1 - 4.2 7.5 18.8 0.49 10.5 2.3 3.4 2 1 1 3 3 3 0 Cysteine rich domain with multizinc binding regions zf-C2H2_6 PF13912.6 KFP09585.1 - 4.9 7.3 32.0 4.5 7.4 0.4 5.8 5 1 0 5 5 5 0 C2H2-type zinc finger zf-trcl PF13451.6 KFP09585.1 - 8.5 6.4 16.6 41 4.2 0.1 5.0 4 1 0 4 4 4 0 Probable zinc-ribbon domain BolA PF01722.18 KFP09585.1 - 8.9 6.7 7.0 13 6.2 1.2 3.2 1 1 1 2 2 2 0 BolA-like protein AKAP7_RIRII_bdg PF10470.9 KFP09586.1 - 4e-06 26.8 4.2 4.1e-06 26.7 4.2 1.1 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein DHC_N1 PF08385.12 KFP09588.1 - 2.3e-164 548.1 12.3 2.3e-164 548.1 12.3 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFP09588.1 - 9.3e-144 478.4 0.0 6.4e-143 475.6 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP09588.1 - 3.6e-124 414.9 3.0 3.6e-124 414.9 3.0 3.9 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFP09588.1 - 8.8e-95 317.4 4.6 8.3e-94 314.2 0.0 4.1 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFP09588.1 - 1.2e-94 316.5 0.0 4.3e-94 314.7 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFP09588.1 - 2.5e-83 278.6 8.2 6.1e-82 274.0 4.6 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFP09588.1 - 6.5e-69 231.1 0.6 2.4e-63 212.9 0.1 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFP09588.1 - 1.8e-54 184.0 0.1 4.9e-54 182.5 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFP09588.1 - 7e-46 156.8 8.3 1.3e-45 155.9 8.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFP09588.1 - 1.2e-41 141.5 0.1 3.9e-40 136.7 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFP09588.1 - 2.1e-22 79.6 0.0 2.1e-07 31.0 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KFP09588.1 - 2.4e-19 69.7 0.2 3e-18 66.1 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KFP09588.1 - 7.3e-18 64.6 0.0 9.2e-17 61.1 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KFP09588.1 - 1.1e-07 32.3 0.1 1.3 9.5 0.0 4.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP09588.1 - 9.1e-06 26.0 0.6 1.3 9.3 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KFP09588.1 - 5.7e-05 23.6 0.1 3 8.2 0.0 4.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 KFP09588.1 - 0.002 18.3 1.1 2.1 8.5 0.0 4.5 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 KFP09588.1 - 0.0038 16.6 3.0 0.65 9.3 0.2 3.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFP09588.1 - 0.0054 17.3 0.0 22 5.6 0.0 4.4 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KFP09588.1 - 0.019 14.7 0.0 4.1 7.1 0.0 3.7 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.13 KFP09588.1 - 0.05 12.8 0.0 0.5 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KFP09588.1 - 0.055 14.0 1.3 9.7 6.7 0.0 4.0 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 KFP09588.1 - 0.11 12.9 0.2 21 5.5 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_19 PF13245.6 KFP09588.1 - 0.17 12.2 11.5 9.9 6.5 0.0 5.3 4 0 0 4 4 4 0 AAA domain Pup PF05639.11 KFP09588.1 - 4 8.4 5.8 9.8 7.2 0.9 3.1 2 0 0 2 2 2 0 Pup-like protein 7tm_2 PF00002.24 KFP09589.1 - 2.9e-81 272.4 24.3 4.4e-81 271.8 24.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP09589.1 - 1.7e-15 57.1 3.4 4.3e-15 55.8 3.4 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFP09589.1 - 5.4e-06 25.7 16.9 1e-05 24.9 16.9 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ion_trans_2 PF07885.16 KFP09590.1 - 2.6e-30 104.2 19.6 8.5e-18 64.1 2.0 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFP09590.1 - 0.0051 16.1 9.9 0.018 14.3 0.4 2.4 2 1 0 2 2 2 2 Ion transport protein EGF_CA PF07645.15 KFP09591.1 - 9.1e-49 163.4 89.9 6.5e-14 51.9 7.7 8.0 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.7 KFP09591.1 - 5.2e-36 122.2 49.7 2.4e-10 40.1 0.6 7.3 7 0 0 7 7 7 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP09591.1 - 8.5e-10 38.7 87.6 6.4e-07 29.6 6.9 7.8 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP09591.1 - 2.9e-08 33.8 88.8 0.00031 21.0 6.2 8.4 9 1 0 9 9 9 5 EGF-like domain EGF_3 PF12947.7 KFP09591.1 - 0.00012 22.2 8.4 0.00012 22.2 8.4 8.6 7 2 1 8 8 8 4 EGF domain EGF_MSP1_1 PF12946.7 KFP09591.1 - 0.00023 21.1 45.5 0.034 14.2 1.6 6.9 5 1 1 6 6 6 3 MSP1 EGF domain 1 hEGF PF12661.7 KFP09591.1 - 0.0022 18.5 3.8 0.0022 18.5 3.8 10.8 12 0 0 12 12 12 5 Human growth factor-like EGF RNase_PH PF01138.21 KFP09592.1 - 5.7e-42 143.3 0.0 2.2e-21 76.7 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP09592.1 - 6.8e-15 54.9 1.0 1.1e-09 38.2 0.1 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 KFP09592.1 - 2.4e-09 37.5 0.2 7.4e-09 36.0 0.2 1.9 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 KFP09592.1 - 2.3e-06 27.8 0.0 1.1e-05 25.6 0.0 2.2 3 0 0 3 3 3 1 S1 RNA binding domain KH_1 PF00013.29 KFP09592.1 - 5.9e-06 26.0 0.0 7.8e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 KH domain OAF PF14941.6 KFP09592.1 - 0.023 14.2 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator, Out at first ProQ_C PF17516.2 KFP09592.1 - 0.025 14.0 0.1 2.9 7.4 0.1 3.3 2 1 0 2 2 2 0 ProQ C-terminal domain SMK-1 PF04802.15 KFP09593.1 - 2.3e-61 207.0 5.0 2.3e-61 207.0 5.0 2.1 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 IGF2_C PF08365.11 KFP09593.1 - 0.0044 17.0 0.2 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide ARL2_Bind_BART PF11527.8 KFP09594.1 - 9.7e-26 90.2 5.2 9.7e-26 90.2 5.2 1.5 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Ppx-GppA PF02541.16 KFP09594.1 - 0.0048 16.4 1.2 0.0063 16.0 1.2 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Reticulon PF02453.17 KFP09594.1 - 0.035 14.1 0.1 0.053 13.5 0.1 1.2 1 0 0 1 1 1 0 Reticulon IL31 PF15209.6 KFP09594.1 - 0.12 12.1 2.2 0.1 12.4 0.6 1.7 1 1 1 2 2 2 0 Interleukin 31 HOOK PF05622.12 KFP09595.1 - 1.6e-35 122.5 67.6 1.6e-35 122.5 67.6 5.2 1 1 3 5 5 5 2 HOOK protein APG6_N PF17675.1 KFP09595.1 - 0.00083 19.9 13.0 0.00083 19.9 13.0 14.9 2 1 11 13 13 13 4 Apg6 coiled-coil region GAS PF13851.6 KFP09595.1 - 0.0017 17.7 27.9 0.0017 17.7 27.9 12.5 1 1 10 12 12 12 6 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 KFP09595.1 - 0.004 17.9 16.9 0.004 17.9 16.9 15.1 4 3 12 16 16 16 3 Domain of unknown function (DUF4472) tRNA_edit PF04073.15 KFP09596.1 - 2.9e-24 85.5 0.0 3.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HTH_10 PF04967.12 KFP09596.1 - 0.1 12.4 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain GTP_EFTU PF00009.27 KFP09597.1 - 1.9e-32 112.4 8.8 2.2e-32 112.2 3.2 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFP09597.1 - 1e-31 109.1 1.2 1e-31 109.1 1.2 2.5 4 0 0 4 4 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KFP09597.1 - 1.1e-09 38.4 0.1 3.4e-09 36.8 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFP09597.1 - 7.3e-05 22.3 0.0 0.00026 20.5 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP09597.1 - 0.001 18.7 0.0 0.0031 17.1 0.0 1.9 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP09597.1 - 0.0021 17.5 0.5 0.016 14.7 0.2 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KFP09597.1 - 0.0021 18.0 1.0 3 7.9 0.0 2.8 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFP09597.1 - 0.0025 17.3 0.9 0.006 16.1 0.1 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KFP09597.1 - 0.0042 17.3 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KFP09597.1 - 0.005 16.9 0.6 2.9 7.9 0.0 3.5 2 1 1 3 3 3 1 Dynamin family GTP_EFTU_D4 PF14578.6 KFP09597.1 - 0.018 14.9 0.5 0.066 13.1 0.2 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_26 PF13500.6 KFP09597.1 - 0.048 13.5 0.5 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain IF2_N PF04760.15 KFP09597.1 - 0.049 13.5 1.3 0.74 9.7 0.1 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 KFP09597.1 - 0.11 12.9 0.5 7.5 7.0 0.0 3.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 PDZ_4 PF17816.1 KFP09597.1 - 0.46 10.9 3.1 13 6.2 0.0 3.2 2 1 0 2 2 2 0 PDZ domain AAA_23 PF13476.6 KFP09597.1 - 5.1 7.5 0.0 5.1 7.5 0.0 3.4 3 1 0 3 3 2 0 AAA domain Ribosomal_S27 PF01599.19 KFP09598.1 - 2.2e-28 98.1 4.1 4.5e-28 97.2 4.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 KFP09598.1 - 6.9e-27 93.0 0.4 1.2e-26 92.2 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KFP09598.1 - 1.7e-11 43.8 0.1 3.7e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFP09598.1 - 1.8e-05 25.1 0.3 0.00011 22.6 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFP09598.1 - 0.00058 19.9 0.5 0.001 19.2 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KFP09598.1 - 0.0065 16.4 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KFP09598.1 - 0.014 16.0 0.6 0.019 15.5 0.6 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFP09598.1 - 0.024 15.0 1.0 0.044 14.1 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KFP09598.1 - 0.034 14.4 4.4 0.053 13.7 4.4 1.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Reticulon PF02453.17 KFP09599.1 - 4.5e-25 88.5 1.2 6.8e-25 87.9 1.2 1.3 1 0 0 1 1 1 1 Reticulon WD40 PF00400.32 KFP09600.1 - 1.5e-67 221.8 87.2 7.2e-05 23.5 0.0 28.5 31 0 0 31 31 31 13 WD domain, G-beta repeat HELP PF03451.14 KFP09600.1 - 3.7e-57 190.1 2.8 2.4e-20 72.2 0.1 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 KFP09600.1 - 2e-38 130.5 10.9 1.4e-07 31.7 0.0 13.2 9 4 3 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP09600.1 - 7.2e-12 44.9 1.2 0.014 14.4 0.0 7.7 5 3 3 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFP09600.1 - 7.7e-07 28.0 8.2 0.068 11.7 0.0 6.5 6 1 0 6 6 6 2 Cytochrome D1 heme domain WD40_like PF17005.5 KFP09600.1 - 1.3e-06 27.9 2.8 1.2 8.4 0.0 7.4 8 1 0 8 8 8 2 WD40-like domain Frtz PF11768.8 KFP09600.1 - 2.3e-05 22.9 0.0 0.014 13.8 0.0 4.0 3 1 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KFP09600.1 - 2.4e-05 24.1 0.5 49 4.0 0.0 6.9 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 KFP09600.1 - 9.8e-05 21.3 0.0 0.28 9.9 0.0 4.2 4 0 0 4 4 4 1 Nup133 N terminal like Coatomer_WDAD PF04053.14 KFP09600.1 - 0.0039 16.3 0.2 9.1 5.2 0.0 4.9 5 2 1 6 6 6 2 Coatomer WD associated region Nbas_N PF15492.6 KFP09600.1 - 0.025 13.9 0.1 17 4.6 0.0 4.4 5 1 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KFP09600.1 - 0.032 12.9 0.4 35 2.9 0.1 4.2 4 1 1 5 5 5 0 Nucleoporin Nup120/160 PSII_BNR PF14870.6 KFP09600.1 - 0.2 10.9 2.1 5.1 6.3 0.0 3.3 4 0 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 Acylphosphatase PF00708.18 KFP09601.1 - 7.3e-16 58.4 0.0 8.2e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase LRR_8 PF13855.6 KFP09602.1 - 4.2e-39 132.1 36.1 6.4e-11 41.8 0.9 9.4 4 3 6 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFP09602.1 - 4.7e-26 90.4 54.3 1.7e-05 25.1 0.7 10.8 8 3 4 12 12 12 8 Leucine Rich repeats (2 copies) TIR PF01582.20 KFP09602.1 - 2e-22 79.8 0.1 3.5e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KFP09602.1 - 1.6e-17 64.2 0.0 3.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.33 KFP09602.1 - 2.3e-08 33.5 41.9 0.94 10.3 0.0 14.6 14 4 1 15 15 15 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP09602.1 - 5.5e-06 26.0 37.4 1.8 8.8 0.1 12.3 13 0 0 13 13 13 3 Leucine Rich repeat LRR_9 PF14580.6 KFP09602.1 - 0.00099 18.7 15.3 0.37 10.3 0.3 5.0 3 1 2 5 5 5 3 Leucine-rich repeat LRR_5 PF13306.6 KFP09602.1 - 0.47 10.4 11.0 4.3 7.3 0.4 4.0 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 KFP09602.1 - 4.9 7.4 16.6 16 5.8 0.1 5.9 5 2 0 5 5 5 0 FNIP Repeat ChaC PF04752.12 KFP09603.1 - 2.8e-41 141.5 0.0 3.2e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 KFP09603.1 - 0.079 13.6 0.0 0.099 13.2 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like Ank_2 PF12796.7 KFP09604.1 - 8.6e-52 173.7 0.0 1.9e-13 50.8 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09604.1 - 4.1e-46 154.8 0.3 8.7e-12 45.3 0.0 6.7 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP09604.1 - 3.1e-35 116.2 0.6 0.00011 22.3 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KFP09604.1 - 8.8e-35 117.6 3.4 5.1e-05 23.5 0.0 9.1 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFP09604.1 - 3.9e-34 116.3 0.4 5.7e-07 29.7 0.1 7.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP09604.1 - 2e-10 40.9 4.3 4e-10 39.9 4.3 1.5 1 0 0 1 1 1 1 SOCS box MARVEL PF01284.23 KFP09605.1 - 1.1e-09 38.4 12.9 1.3e-09 38.2 12.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KFP09605.1 - 6.8 4.9 11.5 7.5 4.7 11.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SH3_1 PF00018.28 KFP09606.1 - 4.1e-13 48.7 0.1 1.2e-12 47.2 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP09606.1 - 1.5e-11 43.8 0.0 3.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP09606.1 - 3.3e-10 39.7 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TRAP_alpha PF03896.16 KFP09606.1 - 0.046 12.9 9.0 0.072 12.3 7.8 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SH3_10 PF17902.1 KFP09606.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 SH3 domain CobT PF06213.12 KFP09606.1 - 0.29 10.5 11.7 0.6 9.5 11.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 KFP09606.1 - 0.43 8.6 21.1 0.83 7.7 21.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFP09606.1 - 1.4 7.1 11.5 2.8 6.1 11.5 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 KFP09606.1 - 2.8 7.0 18.2 4.4 6.3 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 KFP09606.1 - 4 5.5 17.2 5.5 5.1 17.2 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFP09606.1 - 4.2 6.6 16.0 6.5 6.0 16.0 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KFP09606.1 - 4.3 7.0 16.8 12 5.5 16.8 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KFP09606.1 - 5.7 6.2 13.9 11 5.3 13.9 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4820 PF16091.5 KFP09606.1 - 6.6 6.0 8.1 13 5.1 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ion_trans PF00520.31 KFP09607.1 - 1.5e-18 66.9 24.2 2e-18 66.5 24.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KFP09608.1 - 1.9e-10 40.4 10.3 2.2e-10 40.2 10.3 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5313 PF17240.2 KFP09608.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) PKD_channel PF08016.12 KFP09608.1 - 0.26 9.9 6.2 0.45 9.1 6.2 1.3 1 0 0 1 1 1 0 Polycystin cation channel DUF4083 PF13314.6 KFP09608.1 - 3.1 7.8 7.8 0.1 12.6 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Mad3_BUB1_I PF08311.12 KFP09609.1 - 4.7e-34 117.0 0.0 2.2e-33 114.9 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFP09609.1 - 7.4e-16 58.3 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09609.1 - 5e-07 29.3 0.0 8.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP09609.1 - 0.038 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFP09609.1 - 0.16 10.7 2.7 0.19 10.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase AAA_23 PF13476.6 KFP09609.1 - 2 8.9 9.9 0.56 10.7 6.4 1.8 2 0 0 2 2 2 0 AAA domain zf-CpG_bind_C PF12269.8 KFP09609.1 - 2.9 7.6 6.1 15 5.3 0.1 2.5 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain PTPLA PF04387.14 KFP09610.1 - 2.6e-38 131.4 9.1 4.1e-38 130.7 9.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Interferon PF00143.19 KFP09611.1 - 1.2e-48 165.3 10.5 1.4e-48 165.1 10.5 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain CLASP_N PF12348.8 KFP09612.1 - 3.7e-53 180.4 5.1 2.7e-36 125.2 0.1 4.3 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KFP09612.1 - 2.8e-15 55.1 10.8 0.0041 17.3 0.0 9.9 10 0 0 10 10 8 3 HEAT repeat HEAT_EZ PF13513.6 KFP09612.1 - 1.3e-09 38.3 1.6 0.046 14.2 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 KFP09612.1 - 3.4e-09 37.0 1.3 0.86 10.0 0.3 8.1 6 3 4 10 10 10 2 HEAT repeats Cnd1 PF12717.7 KFP09612.1 - 1.9e-08 34.6 10.0 0.0096 16.0 0.5 6.5 6 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFP09612.1 - 1.5e-07 31.6 3.3 0.017 15.3 0.1 4.0 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFP09612.1 - 6.8e-06 24.9 4.4 0.34 9.4 0.1 6.0 5 1 0 6 6 6 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KFP09612.1 - 6.5e-05 23.4 2.5 25 5.5 0.0 6.1 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 KFP09612.1 - 0.00011 22.1 4.9 3 7.7 1.3 4.7 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal ParcG PF10274.9 KFP09612.1 - 0.00033 20.8 3.5 0.0026 17.9 0.1 3.4 3 1 1 4 4 4 1 Parkin co-regulated protein TFCD_C PF12612.8 KFP09612.1 - 0.00089 19.1 0.4 0.1 12.4 0.1 4.1 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal MMS19_N PF14500.6 KFP09612.1 - 0.00099 18.8 4.7 4.4 6.8 0.1 3.8 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KFP09612.1 - 0.0042 16.3 6.4 1.1 8.3 0.1 4.0 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 KFP09612.1 - 0.036 14.7 2.4 0.43 11.2 0.0 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation TAN PF11640.8 KFP09612.1 - 0.14 12.3 0.1 0.14 12.3 0.1 3.9 4 1 1 5 5 3 0 Telomere-length maintenance and DNA damage repair R3H PF01424.22 KFP09613.1 - 3.2e-12 46.3 0.6 9.3e-12 44.8 0.1 2.1 2 0 0 2 2 2 1 R3H domain STAC2_u1 PF16664.5 KFP09614.1 - 1.4e-29 103.2 0.1 1.4e-29 103.2 0.1 2.9 2 1 0 3 3 3 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SH3_9 PF14604.6 KFP09614.1 - 3e-19 68.6 0.0 1.3e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP09614.1 - 7.4e-17 60.7 0.5 1e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP09614.1 - 7.3e-16 57.6 0.1 4.8e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KFP09614.1 - 2.1e-10 40.3 10.6 5.2e-10 39.1 10.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFP09614.1 - 0.0012 18.9 2.4 0.0021 18.1 2.4 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon C1_2 PF03107.16 KFP09614.1 - 0.016 15.5 3.2 0.016 15.5 3.2 2.0 2 0 0 2 2 2 0 C1 domain RNA_POL_M_15KD PF02150.16 KFP09614.1 - 0.091 12.7 1.3 0.19 11.6 1.3 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PHD PF00628.29 KFP09614.1 - 0.096 12.6 8.2 0.21 11.5 8.2 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFP09614.1 - 0.49 10.5 6.8 0.21 11.7 4.0 1.8 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING-like PF08746.11 KFP09614.1 - 2.1 8.8 10.4 5.3 7.4 10.4 1.7 1 0 0 1 1 1 0 RING-like domain Ndc1_Nup PF09531.10 KFP09614.1 - 3.7 6.1 5.6 5.2 5.6 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 KFP09615.1 - 8e-82 274.6 0.0 9.4e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09615.1 - 2.2e-37 128.8 0.0 2.8e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP09615.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP09615.1 - 0.0037 16.1 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP09615.1 - 0.0055 16.1 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KFP09615.1 - 0.034 13.7 4.3 0.056 13.0 0.1 2.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.23 KFP09615.1 - 0.082 12.8 0.1 0.42 10.5 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family UvrD_C PF13361.6 KFP09616.1 - 5.9e-08 32.5 0.1 0.0006 19.3 0.0 4.6 4 1 1 5 5 5 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KFP09616.1 - 6e-07 29.3 2.5 6e-07 29.3 2.5 4.2 3 3 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KFP09616.1 - 2.7e-06 27.1 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Ank_2 PF12796.7 KFP09616.1 - 4.9e-06 27.0 0.0 1.9e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09616.1 - 0.0019 18.7 0.1 0.054 14.1 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_19 PF13245.6 KFP09616.1 - 0.0038 17.6 0.0 0.93 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain Ank PF00023.30 KFP09616.1 - 0.042 14.3 0.0 1.6 9.3 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Clathrin PF00637.20 KFP09616.1 - 0.048 13.5 21.2 0.12 12.3 0.4 4.9 5 1 1 6 6 6 0 Region in Clathrin and VPS RcsF PF16358.5 KFP09616.1 - 0.27 11.3 3.4 8.6 6.5 0.0 3.3 2 1 1 3 3 3 0 RcsF lipoprotein TPR_2 PF07719.17 KFP09617.1 - 0.00054 19.9 0.1 1.6 9.0 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP09617.1 - 0.0043 16.8 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP09617.1 - 0.029 14.7 0.0 6.1 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFP09617.1 - 0.068 13.2 0.0 6.6 6.8 0.1 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KFP09617.1 - 0.15 12.7 0.1 11 6.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Mlh1_C PF16413.5 KFP09618.1 - 4.6e-99 331.2 0.4 6.9e-99 330.6 0.4 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KFP09618.1 - 3.4e-34 117.1 0.2 6.2e-34 116.2 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KFP09618.1 - 0.0002 21.9 0.4 0.00066 20.2 0.2 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP09618.1 - 0.001 18.9 0.1 0.0035 17.2 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAF1 PF04857.20 KFP09618.1 - 0.0068 15.6 0.3 0.13 11.5 0.0 2.1 1 1 1 2 2 2 1 CAF1 family ribonuclease MENTAL PF10457.9 KFP09619.1 - 9.7e-64 214.4 5.1 1.2e-63 214.2 5.1 1.1 1 0 0 1 1 1 1 Cholesterol-capturing domain Pkinase PF00069.25 KFP09624.1 - 7.4e-74 248.4 0.0 1.1e-72 244.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09624.1 - 6.8e-29 100.9 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP09624.1 - 1.2e-18 67.5 4.8 2.2e-18 66.6 4.8 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 KFP09624.1 - 8.2e-11 42.3 0.3 1.6e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFP09624.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP09624.1 - 0.0075 15.1 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RUN PF02759.19 KFP09625.1 - 1.2e-36 125.7 0.1 4e-36 124.0 0.0 2.0 2 0 0 2 2 2 1 RUN domain RabGAP-TBC PF00566.18 KFP09625.1 - 5.2e-34 117.8 5.7 1.6e-32 113.0 3.8 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFP09625.1 - 1.6e-33 115.6 0.0 3e-32 111.4 0.0 2.6 1 1 0 1 1 1 1 Rab-binding domain (RBD) Omega-toxin PF06357.11 KFP09625.1 - 5.3 6.9 8.8 0.26 11.1 2.3 2.1 2 0 0 2 2 2 0 Omega-atracotoxin SNF PF00209.18 KFP09626.1 - 3.1e-59 201.0 14.6 1.2e-41 143.0 8.0 2.9 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family Toxin_4 PF00706.17 KFP09626.1 - 0.48 10.9 4.8 1.3 9.5 1.2 2.9 3 0 0 3 3 3 0 Anenome neurotoxin GPCR_chapero_1 PF11904.8 KFP09627.1 - 1.2e-97 327.1 0.1 1.2e-97 327.1 0.1 1.6 2 0 0 2 2 2 1 GPCR-chaperone Ank_4 PF13637.6 KFP09627.1 - 1.9e-11 44.3 0.0 4.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP09627.1 - 7.1e-11 42.6 0.0 1.8e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP09627.1 - 8.5e-10 38.0 0.0 0.0022 18.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP09627.1 - 7.4e-09 35.7 0.0 4.3e-06 26.9 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP09627.1 - 2.2e-07 31.0 0.0 0.011 16.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat UIM PF02809.20 KFP09627.1 - 0.15 12.0 20.1 0.28 11.2 1.6 4.3 4 0 0 4 4 4 0 Ubiquitin interaction motif GIT1_C PF12205.8 KFP09628.1 - 2.8e-46 156.4 4.6 2.8e-46 156.4 4.6 2.7 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_CC PF16559.5 KFP09628.1 - 5.6e-28 96.6 6.5 2.1e-27 94.8 6.5 2.1 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor GIT_SHD PF08518.11 KFP09628.1 - 2.6e-27 94.1 1.6 7.9e-14 51.0 0.1 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.18 KFP09628.1 - 2.8e-24 85.4 0.0 2.8e-24 85.4 0.0 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 KFP09628.1 - 5.5e-09 36.5 0.0 1.9e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09628.1 - 3.5e-08 33.8 0.0 4.7e-05 23.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP09628.1 - 3.7e-07 30.3 0.0 1.6e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP09628.1 - 0.001 19.4 0.3 0.0091 16.4 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFP09628.1 - 0.01 16.3 0.0 0.35 11.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Sen15 PF09631.10 KFP09628.1 - 0.012 16.0 0.2 0.059 13.7 0.0 2.3 2 0 0 2 2 2 0 Sen15 protein TTRAP PF14203.6 KFP09628.1 - 0.032 14.2 0.6 0.24 11.4 0.1 2.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein Shugoshin_N PF07558.11 KFP09628.1 - 0.084 12.8 7.0 0.28 11.1 7.0 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DMPK_coil PF08826.10 KFP09628.1 - 0.11 12.6 2.1 0.35 11.0 1.1 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like T7SS_ESX_EspC PF10824.8 KFP09628.1 - 0.52 10.8 4.3 1.7 9.1 0.1 3.5 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm CRIC_ras_sig PF10534.9 KFP09628.1 - 8.3 6.7 10.6 0.45 10.7 0.3 4.1 5 1 1 6 6 5 0 Connector enhancer of kinase suppressor of ras TPH PF13868.6 KFP09629.1 - 6.5e-25 87.4 130.1 7.3e-25 87.2 130.1 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain GLTP PF08718.11 KFP09630.1 - 1.2e-29 103.5 0.0 1.6e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) LRR_8 PF13855.6 KFP09631.1 - 2.8e-27 94.2 45.2 2.7e-09 36.6 5.8 3.7 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP09631.1 - 1.9e-16 59.9 21.4 8e-06 26.1 3.8 4.3 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP09631.1 - 1.9e-09 36.8 16.2 1.5 9.6 0.2 6.5 6 1 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 KFP09631.1 - 5.8e-06 25.9 17.4 3.8 7.8 0.0 6.3 6 0 0 6 6 6 5 Leucine Rich repeat LRR_9 PF14580.6 KFP09631.1 - 0.00027 20.5 5.7 0.022 14.2 1.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat C1q PF00386.21 KFP09632.1 - 2.6e-18 66.5 0.0 2.8e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFP09632.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family PTE PF02126.18 KFP09633.1 - 5.7e-121 403.5 0.0 6.5e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.21 KFP09633.1 - 5.1e-07 29.3 0.0 8.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase ArgoMid PF16487.5 KFP09634.1 - 0.05 13.9 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 Mid domain of argonaute DUF4205 PF13898.6 KFP09635.1 - 1.4e-53 182.0 0.1 7.2e-50 169.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) UPF0560 PF10577.9 KFP09636.1 - 0 1318.4 6.7 0 1318.2 6.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 FAM176 PF14851.6 KFP09636.1 - 0.031 13.9 4.4 7.3 6.2 3.0 2.7 2 0 0 2 2 2 0 FAM176 family Orthoreo_P10 PF07204.11 KFP09636.1 - 0.11 12.4 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 SspO PF08175.12 KFP09636.1 - 0.15 12.5 1.1 1.6 9.2 0.2 2.6 2 0 0 2 2 2 0 Small acid-soluble spore protein O family Adeno_E3_CR2 PF02439.15 KFP09636.1 - 0.24 11.2 1.5 0.44 10.3 1.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Trypan_PARP PF05887.11 KFP09636.1 - 2.1 8.3 6.3 4.2 7.4 6.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NMT_C PF02799.15 KFP09637.1 - 7e-82 274.0 0.2 1.2e-81 273.3 0.2 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFP09637.1 - 2.7e-76 254.8 0.0 5.3e-76 253.9 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFP09637.1 - 0.00021 21.5 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFP09637.1 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP09637.1 - 0.18 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L7Ae PF01248.26 KFP09639.1 - 2.1e-08 33.8 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFP09639.1 - 5.5e-06 26.5 0.1 0.00089 19.3 0.0 2.2 1 1 0 2 2 2 2 RNase P subunit Pop3 ACBP PF00887.19 KFP09640.1 - 2.5e-29 101.3 0.5 2.8e-29 101.2 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein JmjN PF02375.17 KFP09640.1 - 0.05 13.6 1.2 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 jmjN domain RPEL PF02755.15 KFP09640.1 - 0.34 10.7 0.3 0.34 10.7 0.3 1.8 2 0 0 2 2 2 0 RPEL repeat Carn_acyltransf PF00755.20 KFP09641.1 - 9e-174 579.3 0.0 1e-173 579.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RUN PF02759.19 KFP09643.1 - 3.7e-25 88.4 0.1 1.1e-24 87.0 0.0 1.8 2 0 0 2 2 2 1 RUN domain DUF4477 PF14780.6 KFP09643.1 - 0.014 15.0 0.3 0.065 12.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Drf_FH3 PF06367.16 KFP09643.1 - 0.044 13.4 5.4 0.095 12.3 5.4 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain Mito_carr PF00153.27 KFP09644.1 - 7.1e-61 202.2 0.7 9.2e-22 76.8 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 KFP09644.1 - 0.054 13.4 0.5 9 6.3 0.0 2.8 3 0 0 3 3 3 0 UcrQ family zf-DBF PF07535.12 KFP09645.1 - 1.1e-17 63.8 2.7 3.6e-17 62.2 2.7 2.0 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 KFP09645.1 - 0.0061 16.9 0.1 0.034 14.5 0.1 2.4 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DnaI_N PF07319.11 KFP09645.1 - 0.5 11.1 3.8 0.76 10.5 0.6 2.9 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Reprolysin PF01421.19 KFP09646.1 - 4.1e-61 206.4 0.0 1e-60 205.1 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP09646.1 - 7.7e-28 97.2 7.3 7.7e-28 97.2 7.3 3.9 3 2 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP09646.1 - 1.6e-15 57.5 1.8 1.6e-15 57.5 1.8 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide Disintegrin PF00200.23 KFP09646.1 - 3.2e-15 56.7 30.4 3.2e-15 56.7 30.4 4.0 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFP09646.1 - 7.6e-08 32.9 0.0 1.5e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP09646.1 - 2.4e-06 27.9 0.0 6.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 EGF_2 PF07974.13 KFP09646.1 - 0.0012 19.1 10.8 0.0012 19.1 10.8 6.3 4 2 0 4 4 4 1 EGF-like domain ADAM_CR_2 PF17771.1 KFP09646.1 - 0.05 14.1 0.4 0.05 14.1 0.4 6.0 4 1 2 6 6 6 0 ADAM cysteine-rich domain FRP PF18032.1 KFP09646.1 - 0.2 12.3 0.2 0.41 11.3 0.2 1.4 1 0 0 1 1 1 0 Photoprotection regulator fluorescence recovery protein EF-hand_1 PF00036.32 KFP09647.1 - 1.5e-17 61.8 1.0 0.00036 19.9 0.0 5.4 5 1 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP09647.1 - 3.2e-14 51.5 0.3 6.8e-05 22.5 0.1 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KFP09647.1 - 4.6e-14 52.0 2.0 2.2e-10 40.2 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 KFP09647.1 - 3e-12 46.8 0.2 0.00029 21.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP09647.1 - 1.7e-11 43.1 1.6 0.0014 18.0 0.1 3.8 4 0 0 4 4 4 3 EF hand VbhA PF18495.1 KFP09647.1 - 0.058 13.3 0.1 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Antitoxin VbhA DUF2835 PF11197.8 KFP09647.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Ferric_reduct PF01794.19 KFP09648.1 - 1.1e-12 48.1 11.4 1.9e-12 47.4 6.9 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component F420_oxidored PF03807.17 KFP09648.1 - 2.6e-12 47.2 0.1 4.4e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KFP09648.1 - 1.7e-05 24.5 0.1 2.9e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KFP09648.1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFP09648.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KFP09648.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_7 PF13241.6 KFP09648.1 - 0.062 13.7 0.1 0.36 11.3 0.1 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KFP09648.1 - 0.11 12.5 0.1 0.71 9.8 0.0 2.0 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ferric_reduct PF01794.19 KFP09651.1 - 4e-13 49.6 15.1 1.2e-11 44.8 5.0 2.6 2 1 1 3 3 3 2 Ferric reductase like transmembrane component DUF999 PF06198.11 KFP09651.1 - 1.1 9.3 5.9 0.79 9.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF999) MgtE PF01769.16 KFP09651.1 - 7.1 7.0 9.7 4.5 7.7 3.5 2.5 2 1 0 2 2 2 0 Divalent cation transporter F420_oxidored PF03807.17 KFP09652.1 - 4.7e-18 65.6 0.0 8.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 KFP09652.1 - 3.4e-15 56.3 9.0 1.6e-14 54.1 5.2 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 KFP09652.1 - 4.7e-05 23.6 0.0 8.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFP09652.1 - 0.0036 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFP09652.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2768 PF10966.8 KFP09652.1 - 0.049 14.1 3.0 0.19 12.2 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) IlvN PF07991.12 KFP09652.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KFP09652.1 - 0.15 12.6 0.0 0.48 10.9 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding MMR_HSR1 PF01926.23 KFP09655.1 - 4e-23 81.7 0.0 7.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KFP09655.1 - 1.2e-16 60.7 6.0 7.2e-16 58.2 6.0 2.0 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 KFP09655.1 - 4.8e-12 45.7 0.0 4e-11 42.7 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KFP09655.1 - 0.00011 21.8 0.0 0.006 16.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFP09655.1 - 0.00018 20.6 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFP09655.1 - 0.022 14.8 0.3 4.4 7.3 0.0 2.6 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KFP09655.1 - 0.069 12.9 0.3 0.43 10.3 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Claudin_2 PF13903.6 KFP09656.1 - 0.028 14.2 14.4 0.24 11.1 14.3 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.6 KFP09657.1 - 0.00023 22.0 0.1 0.00036 21.3 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KFP09657.1 - 0.0025 18.5 1.2 0.005 17.6 1.2 1.5 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal FAM163 PF15069.6 KFP09657.1 - 0.0032 18.0 0.8 0.0049 17.3 0.8 1.3 1 0 0 1 1 1 1 FAM163 family Comm PF15957.5 KFP09657.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Commissureless Prominin PF05478.11 KFP09657.1 - 0.023 12.7 4.2 0.028 12.4 4.2 1.1 1 0 0 1 1 1 0 Prominin LYRIC PF15686.5 KFP09657.1 - 0.034 13.7 0.1 0.045 13.3 0.1 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family CD34_antigen PF06365.12 KFP09657.1 - 0.034 13.7 1.2 0.034 13.7 1.2 1.7 1 1 1 2 2 2 0 CD34/Podocalyxin family DUF4500 PF14937.6 KFP09657.1 - 0.036 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) FAM176 PF14851.6 KFP09657.1 - 0.047 13.3 0.1 0.062 13.0 0.1 1.1 1 0 0 1 1 1 0 FAM176 family MLANA PF14991.6 KFP09657.1 - 0.051 13.9 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A MAP17 PF15807.5 KFP09657.1 - 0.088 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Protocadherin PF08374.11 KFP09657.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 KFP09657.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CCER1 PF15482.6 KFP09657.1 - 0.23 11.3 3.8 0.27 11.1 3.7 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 U79_P34 PF03064.16 KFP09657.1 - 0.61 9.4 4.9 0.82 9.0 4.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SKG6 PF08693.10 KFP09657.1 - 1.1 8.7 8.2 1.8 8.0 8.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Synaptobrevin PF00957.21 KFP09657.1 - 1.2 9.0 3.2 2.3 8.1 3.2 1.4 1 0 0 1 1 1 0 Synaptobrevin Synaphin PF05835.12 KFP09657.1 - 2.2 8.5 11.1 2.9 8.2 11.1 1.1 1 0 0 1 1 1 0 Synaphin protein TMIE PF16038.5 KFP09657.1 - 7.3 6.5 9.2 12 5.8 9.2 1.4 1 1 0 1 1 1 0 TMIE protein Pkinase PF00069.25 KFP09659.1 - 1.3e-67 227.9 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09659.1 - 2.9e-32 112.0 0.0 4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP09659.1 - 3.8e-05 22.8 0.0 0.00013 21.0 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP09659.1 - 0.0017 17.7 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP09659.1 - 0.004 17.1 0.0 0.083 12.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP09659.1 - 0.073 12.7 0.0 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Frizzled PF01534.17 KFP09660.1 - 3.2e-111 371.5 9.1 3.7e-111 371.3 9.1 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 KFP09660.1 - 0.0003 20.0 4.4 0.0003 20.0 4.4 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DHHC PF01529.20 KFP09660.1 - 0.025 14.7 5.4 0.47 10.6 1.5 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF3493 PF11998.8 KFP09660.1 - 0.31 11.2 0.1 0.31 11.2 0.1 1.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF2269 PF10027.9 KFP09660.1 - 2.2 8.3 12.6 0.27 11.3 0.3 2.5 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) PACT_coil_coil PF10495.9 KFP09663.1 - 3.2e-25 88.5 0.1 3.2e-25 88.5 0.1 8.6 8 0 0 8 8 8 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF2525 PF10733.9 KFP09663.1 - 1 9.7 5.8 5.3 7.4 0.5 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2525) NUDIX_5 PF16705.5 KFP09664.1 - 4.1e-85 284.0 0.0 7e-85 283.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX, or N-terminal NPxY motif-rich, region of KRIT FERM_M PF00373.18 KFP09664.1 - 1.5e-19 70.5 1.2 2.4e-19 69.9 0.1 2.0 3 0 0 3 3 3 1 FERM central domain Ank_2 PF12796.7 KFP09664.1 - 3.2e-16 59.7 0.0 1.1e-06 29.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP09664.1 - 1.9e-14 53.5 0.2 1.1e-09 38.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP09664.1 - 1.7e-11 44.4 0.5 5.9e-07 29.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP09664.1 - 3.7e-10 39.8 0.2 0.018 15.4 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFP09664.1 - 7.7e-08 32.0 0.2 0.048 14.2 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat IBR PF01485.21 KFP09665.1 - 4.5e-21 74.8 36.1 2.1e-13 50.3 1.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Ank_5 PF13857.6 KFP09665.1 - 6.3e-11 42.3 0.9 0.00019 21.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP09665.1 - 5.5e-10 39.7 0.4 7.8e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP09665.1 - 2.2e-09 37.3 0.1 0.0033 17.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP09665.1 - 3.1e-07 30.2 0.3 0.013 15.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFP09665.1 - 3.4e-07 30.7 0.1 0.0078 16.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) zf-RING_UBOX PF13445.6 KFP09665.1 - 4.4e-05 23.4 30.6 0.00012 22.0 6.4 4.2 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP09665.1 - 0.00057 19.7 4.9 0.00057 19.7 4.9 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP09665.1 - 0.0012 19.2 8.7 0.0012 19.2 8.7 4.0 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.6 KFP09665.1 - 0.0044 17.2 6.5 0.0044 17.2 6.5 4.1 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFP09665.1 - 0.0056 16.5 6.1 0.0056 16.5 6.1 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UIM PF02809.20 KFP09665.1 - 0.12 12.4 0.7 0.39 10.7 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Sipho_Gp37 PF14594.6 KFP09667.1 - 0.075 12.0 0.1 0.088 11.8 0.1 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein AAA PF00004.29 KFP09668.1 - 2e-58 196.5 0.0 1.5e-42 145.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-2N PF09263.10 KFP09668.1 - 3.1e-22 78.7 0.1 4.6e-21 74.9 0.0 2.6 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFP09668.1 - 6.2e-15 54.7 1.1 2.2e-09 36.9 0.0 3.5 3 0 0 3 3 3 2 AAA+ lid domain PEX-1N PF09262.11 KFP09668.1 - 1.2e-14 54.5 0.0 3.3e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 KFP09668.1 - 4.6e-10 40.1 1.4 0.0031 17.9 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 KFP09668.1 - 1.3e-07 31.9 0.0 0.0033 17.8 0.0 3.8 4 0 0 4 4 3 2 RNA helicase NACHT PF05729.12 KFP09668.1 - 1.3e-06 28.4 5.7 0.012 15.5 0.8 4.9 4 1 0 4 4 4 1 NACHT domain AAA_33 PF13671.6 KFP09668.1 - 1.5e-06 28.5 0.0 0.065 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KFP09668.1 - 1.8e-06 28.2 0.0 0.0012 19.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFP09668.1 - 2.2e-06 27.5 0.0 0.00062 19.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFP09668.1 - 2.8e-06 27.4 0.0 0.0082 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP09668.1 - 3.8e-06 27.5 0.0 0.029 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KFP09668.1 - 5.4e-06 26.3 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 KFP09668.1 - 6.4e-06 26.2 0.2 0.21 11.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFP09668.1 - 1.7e-05 24.1 0.0 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KFP09668.1 - 2.3e-05 24.8 0.1 0.0068 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFP09668.1 - 3.2e-05 23.3 0.3 0.029 13.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain T2SSE PF00437.20 KFP09668.1 - 7.1e-05 22.0 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 KFP09668.1 - 8.3e-05 22.4 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KFP09668.1 - 0.00013 22.2 0.2 0.92 9.8 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.6 KFP09668.1 - 0.00019 21.1 1.6 0.0086 15.8 0.7 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 KFP09668.1 - 0.00019 21.5 0.0 0.17 12.0 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 KFP09668.1 - 0.00027 21.2 0.0 0.72 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFP09668.1 - 0.00029 20.8 0.2 0.77 9.8 0.1 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFP09668.1 - 0.00053 19.6 2.5 1.6 8.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 KFP09668.1 - 0.0014 19.2 4.8 0.07 13.6 0.4 3.6 3 1 1 4 4 3 1 ABC transporter Zeta_toxin PF06414.12 KFP09668.1 - 0.0015 17.9 0.2 0.99 8.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 KFP09668.1 - 0.0015 18.1 0.0 0.76 9.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFP09668.1 - 0.0019 17.6 0.2 1.9 7.8 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KFP09668.1 - 0.0051 16.2 0.1 0.77 9.1 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.6 KFP09668.1 - 0.0066 16.2 0.3 0.75 9.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFP09668.1 - 0.0074 16.0 0.1 4.8 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFP09668.1 - 0.014 15.8 0.5 8.6 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KFP09668.1 - 0.014 15.2 0.0 0.33 10.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial dnaA protein APS_kinase PF01583.20 KFP09668.1 - 0.018 14.9 0.4 0.048 13.6 0.0 1.9 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_23 PF13476.6 KFP09668.1 - 0.032 14.7 0.6 0.24 11.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFP09668.1 - 0.043 13.0 0.2 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Molydop_binding PF01568.21 KFP09668.1 - 0.061 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Rad17 PF03215.15 KFP09668.1 - 0.084 12.8 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 KFP09668.1 - 0.11 12.4 0.4 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 NTPase CoaE PF01121.20 KFP09668.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase Dynamin_N PF00350.23 KFP09668.1 - 0.14 12.2 0.7 23 5.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 KFP09668.1 - 0.19 11.8 0.8 0.53 10.3 0.1 2.2 2 0 0 2 2 1 0 Helicase HerA, central domain Pkinase PF00069.25 KFP09671.1 - 8.2e-69 231.9 0.0 9.5e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09671.1 - 1.3e-35 122.9 0.0 2.5e-35 122.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP09671.1 - 8.9e-07 29.1 0.2 0.0015 18.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP09671.1 - 1.8e-05 24.2 0.0 3.5e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP09671.1 - 0.00016 20.8 0.0 0.00028 19.9 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP09671.1 - 0.002 17.5 0.1 0.0039 16.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFP09671.1 - 0.022 14.4 0.0 0.056 13.0 0.0 1.6 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFP09671.1 - 0.13 11.9 0.0 0.75 9.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ig_3 PF13927.6 KFP09672.1 - 7.2e-22 77.8 0.9 6.8e-12 45.8 0.5 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP09672.1 - 8.6e-18 64.2 0.1 7.7e-09 35.5 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP09672.1 - 1.8e-13 50.5 0.1 6.3e-06 26.3 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP09672.1 - 4.3e-12 46.2 0.6 2.1e-06 28.0 0.2 2.8 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFP09672.1 - 3.1e-11 43.4 0.1 8.8e-06 25.9 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP09672.1 - 0.053 13.1 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Ribosomal_S9 PF00380.19 KFP09672.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Vps54_N PF10475.9 KFP09673.1 - 2.4e-109 365.1 11.9 6.4e-109 363.7 11.9 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KFP09673.1 - 2.7e-96 321.9 3.0 2.7e-96 321.9 3.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DcpS_C PF11969.8 KFP09673.1 - 0.1 13.1 0.6 0.3 11.6 0.6 1.7 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding DUF4298 PF14131.6 KFP09673.1 - 0.54 10.3 7.4 0.74 9.8 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) ERp29 PF07749.12 KFP09673.1 - 0.92 10.5 3.7 3.2 8.7 0.1 3.5 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain 7tm_2 PF00002.24 KFP09674.1 - 3.4e-79 265.6 17.2 4.4e-79 265.2 17.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP09674.1 - 7.6e-20 71.0 7.3 1.8e-19 69.8 7.3 1.7 1 0 0 1 1 1 1 Hormone receptor domain G-gamma PF00631.22 KFP09675.1 - 4.1e-11 42.7 0.0 4.3e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain Acyl-CoA_dh_1 PF00441.24 KFP09677.1 - 1.7e-29 103.0 0.1 8.7e-19 68.2 0.1 2.2 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFP09677.1 - 1.3e-22 79.8 0.1 3.1e-22 78.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFP09677.1 - 1.3e-10 42.0 0.0 3.5e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFP09677.1 - 1.9e-07 31.4 0.2 9.2e-05 22.7 0.0 2.3 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain DUF3011 PF11218.8 KFP09677.1 - 0.16 12.0 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) HpaB_N PF11794.8 KFP09677.1 - 0.2 11.3 0.0 0.45 10.1 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Use1 PF09753.9 KFP09678.1 - 9e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 KFP09678.1 - 0.0002 21.2 0.2 0.00027 20.8 0.2 1.2 1 0 0 1 1 1 1 Sec20 DUF4407 PF14362.6 KFP09678.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MtrB PF05440.12 KFP09678.1 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B RVT_1 PF00078.27 KFP09680.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.18 KFP09683.1 - 4e-164 532.5 675.4 2.2e-09 36.9 38.6 21.0 2 1 12 14 14 14 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFP09683.1 - 3.5e-107 357.0 0.0 4.2e-107 356.7 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Cas1_AcylT PF07779.12 KFP09684.1 - 1.8e-217 722.9 26.7 2.2e-217 722.7 26.7 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KFP09684.1 - 0.085 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p FeoB_associated PF12669.7 KFP09684.1 - 0.18 12.2 0.8 32 5.0 0.1 4.2 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Sarcoglycan_2 PF05510.13 KFP09685.1 - 1.9e-127 425.2 0.0 2.2e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon PDZ_5 PF17817.1 KFP09687.1 - 2.3e-28 98.3 2.1 1.8e-27 95.4 2.1 2.7 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KFP09687.1 - 5.1e-17 61.8 0.4 1.1e-16 60.6 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP09687.1 - 6.4e-14 52.1 0.5 1.7e-13 50.8 0.5 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFP09687.1 - 1e-13 51.4 1.4 2.8e-13 50.0 1.4 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP09687.1 - 2.7e-06 27.1 0.4 2.6e-05 24.0 0.2 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP09687.1 - 0.0036 17.6 0.6 0.016 15.6 0.3 2.2 2 0 0 2 2 2 1 PDZ domain SAM_PNT PF02198.16 KFP09687.1 - 0.032 14.2 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain UPF0154 PF03672.13 KFP09687.1 - 0.05 13.6 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Pox_A_type_inc PF04508.12 KFP09687.1 - 0.075 12.9 1.0 18 5.4 0.3 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PKI PF02827.16 KFP09687.1 - 7.5 6.8 11.4 0.19 11.9 0.5 3.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Arylesterase PF01731.20 KFP09689.1 - 4e-40 135.9 1.6 6.9e-40 135.1 1.6 1.4 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 KFP09689.1 - 3.9e-08 33.2 0.1 5.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KFP09689.1 - 0.0029 17.7 0.0 0.007 16.5 0.0 1.6 1 0 0 1 1 1 1 Strictosidine synthase Glyco_hydro_42C PF08533.10 KFP09689.1 - 0.1 12.3 0.1 0.31 10.8 0.1 1.9 1 1 0 1 1 1 0 Beta-galactosidase C-terminal domain Ank_2 PF12796.7 KFP09690.1 - 3.5e-27 94.8 18.6 1.3e-11 44.9 1.3 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09690.1 - 1.5e-22 79.7 8.9 1.3e-06 28.8 0.3 7.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP09690.1 - 1.2e-17 63.5 12.7 0.12 12.8 0.4 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFP09690.1 - 4.1e-17 60.5 15.4 0.016 15.7 0.0 8.9 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 KFP09690.1 - 2.8e-14 53.0 10.2 0.0043 17.3 0.3 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP09690.1 - 6.3e-10 39.3 5.2 1.4e-09 38.1 5.2 1.7 1 0 0 1 1 1 1 SOCS box BCDHK_Adom3 PF10436.9 KFP09691.1 - 2.2e-48 164.2 0.0 3.1e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFP09691.1 - 6.4e-14 52.4 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP09691.1 - 0.00022 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 KFP09693.1 - 1.4e-08 35.2 9.7 0.061 14.2 0.3 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09693.1 - 0.036 14.4 0.3 1.1 9.6 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 KFP09694.1 - 3.1e-73 241.8 0.5 1.5e-26 92.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFP09694.1 - 5.3e-09 36.4 1.0 0.00083 19.8 0.0 4.9 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP09694.1 - 4.7e-08 32.0 4.6 0.039 13.5 0.2 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KFP09694.1 - 1.4e-07 30.8 2.1 0.0073 16.2 0.2 5.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KFP09694.1 - 2.1e-07 30.7 0.9 0.026 14.3 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP09694.1 - 0.0001 21.6 0.1 0.94 9.1 0.0 3.9 3 0 0 3 3 3 2 EF hand DSS1_SEM1 PF05160.13 KFP09695.1 - 1.1e-13 51.1 10.3 1.1e-13 51.0 10.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Homeodomain PF00046.29 KFP09697.1 - 7.2e-21 73.8 2.4 9.8e-21 73.4 2.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP09697.1 - 0.0028 17.5 0.1 0.0054 16.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF5524 PF17662.1 KFP09697.1 - 0.0091 15.4 0.1 0.41 10.0 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5524) Homez PF11569.8 KFP09697.1 - 0.029 13.8 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFP09697.1 - 0.049 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF3199 PF11436.8 KFP09697.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Tachykinin PF02202.16 KFP09698.1 - 7.3e-11 40.8 1.1 0.00043 19.9 0.9 2.3 2 0 0 2 2 2 2 Tachykinin family Fringe PF02434.16 KFP09699.1 - 7.3e-15 55.1 0.6 3.3e-14 52.9 0.6 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFP09699.1 - 4.5e-09 36.4 0.5 5.2e-05 23.1 0.3 2.2 1 1 1 2 2 2 2 Galactosyltransferase VWA PF00092.28 KFP09700.1 - 2.3e-64 216.9 8.6 9.5e-40 136.7 1.7 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain Collagen PF01391.18 KFP09700.1 - 1.3e-59 197.8 295.3 2.5e-08 33.5 23.6 11.8 1 1 9 10 10 10 8 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFP09700.1 - 1.5e-31 109.2 1.7 4e-19 69.2 0.2 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 KFP09700.1 - 9.3e-10 38.7 1.4 6.5e-06 26.2 0.2 3.0 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP09700.1 - 0.00017 21.0 0.0 0.00039 19.9 0.0 1.5 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein zinc_ribbon_16 PF17034.5 KFP09701.1 - 6.8e-24 84.5 14.3 1.5e-23 83.3 14.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KFP09701.1 - 0.011 15.4 10.8 0.011 15.4 10.8 2.7 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type eIF2A PF08662.11 KFP09701.1 - 0.062 13.2 0.0 5.6 6.8 0.0 3.4 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A CheB_methylest PF01339.17 KFP09701.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 CheB methylesterase Rep_fac-A_3 PF08661.11 KFP09702.1 - 3.9e-19 68.9 0.0 4.2e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF2464 PF10240.9 KFP09703.1 - 0.021 14.4 0.0 0.022 14.3 0.0 1.0 1 0 0 1 1 1 0 Multivesicular body subunit 12 FAM117 PF15388.6 KFP09704.1 - 1.5e-123 412.2 18.6 1.5e-123 412.2 18.6 1.8 2 0 0 2 2 2 1 Protein Family FAM117 Arfaptin PF06456.13 KFP09705.1 - 6.6e-89 297.4 11.9 9.4e-89 296.9 11.9 1.2 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 KFP09705.1 - 7.8e-61 206.6 17.5 1.1e-41 143.9 8.5 2.9 1 1 1 2 2 2 2 Islet cell autoantigen ICA69, C-terminal domain BAR_2 PF10455.9 KFP09705.1 - 0.00084 18.6 2.1 0.0013 18.0 1.5 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ead_Ea22 PF13935.6 KFP09705.1 - 0.26 11.9 2.0 0.64 10.7 1.8 2.0 1 1 0 1 1 1 0 Ead/Ea22-like protein Neurexophilin PF06312.12 KFP09707.1 - 7e-112 372.0 2.7 8.8e-112 371.7 2.7 1.1 1 0 0 1 1 1 1 Neurexophilin NigD_C PF17415.2 KFP09707.1 - 0.063 13.4 0.1 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain Filamin PF00630.19 KFP09707.1 - 0.072 13.9 0.0 0.26 12.1 0.0 1.9 2 0 0 2 2 2 0 Filamin/ABP280 repeat DUF4462 PF14692.6 KFP09711.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) TSP_1 PF00090.19 KFP09712.1 - 1.2e-66 220.8 222.5 4.4e-13 49.2 1.9 23.7 25 1 0 25 25 25 18 Thrombospondin type 1 domain DUF1356 PF07092.12 KFP09713.1 - 1.2e-117 391.2 5.2 1.5e-117 390.9 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KFP09713.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein LEA_2 PF03168.13 KFP09713.1 - 0.11 13.0 0.7 0.49 10.9 0.9 2.0 1 1 1 2 2 2 0 Late embryogenesis abundant protein DnaJ_CXXCXGXG PF00684.19 KFP09713.1 - 0.22 11.9 2.7 0.21 12.0 0.6 2.0 2 1 1 3 3 3 0 DnaJ central domain EGF PF00008.27 KFP09714.1 - 9.4e-15 54.6 58.7 0.00011 22.4 7.7 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.13 KFP09714.1 - 4.4e-14 52.5 66.7 0.0014 19.0 13.2 4.2 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFP09714.1 - 2.2e-08 34.4 33.7 0.00011 22.7 4.2 6.4 8 0 0 8 8 8 4 Human growth factor-like EGF Laminin_EGF PF00053.24 KFP09714.1 - 2.5 8.3 50.6 2.6 8.3 10.9 4.2 1 1 3 4 4 4 0 Laminin EGF domain EGF_2 PF07974.13 KFP09715.1 - 6.2e-22 77.7 79.7 3.1e-05 24.2 7.4 5.1 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 KFP09715.1 - 1.2e-16 60.7 73.3 0.00073 19.8 10.9 5.8 5 1 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFP09715.1 - 1.2e-09 38.4 84.8 0.0019 18.8 9.1 7.4 8 0 0 8 8 8 5 Human growth factor-like EGF Laminin_EGF PF00053.24 KFP09715.1 - 0.018 15.2 66.7 0.4 10.9 7.7 5.2 2 1 3 5 5 5 0 Laminin EGF domain DSL PF01414.19 KFP09715.1 - 0.041 14.2 12.5 0.041 14.2 12.5 3.8 1 1 3 4 4 4 0 Delta serrate ligand EB PF01683.18 KFP09715.1 - 2.5 8.5 64.9 4.8 7.5 3.2 6.1 1 1 4 5 5 5 0 EB module EGF PF00008.27 KFP09716.1 - 1.6e-05 25.1 39.5 0.0012 19.1 5.7 4.4 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KFP09716.1 - 0.017 15.8 16.4 0.021 15.4 6.2 6.1 6 1 0 6 6 6 0 Human growth factor-like EGF VWD PF00094.25 KFP09717.1 - 0.00022 21.5 0.8 0.00039 20.7 0.8 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain Gelsolin PF00626.22 KFP09719.1 - 3.6e-84 276.7 0.1 8.6e-18 64.0 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat Arf PF00025.21 KFP09720.1 - 7.6e-67 224.1 0.0 8.8e-67 223.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP09720.1 - 1.6e-17 63.6 0.0 1.7e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09720.1 - 3.9e-17 62.6 0.1 5.2e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP09720.1 - 2.1e-12 46.8 0.1 2.1e-12 46.8 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP09720.1 - 1.1e-08 34.7 0.6 1.4e-06 27.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP09720.1 - 3.4e-08 33.6 0.1 4.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP09720.1 - 5e-05 22.8 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP09720.1 - 5.3e-05 22.9 0.1 0.00026 20.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP09720.1 - 0.0046 16.8 0.0 0.018 14.8 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 KFP09720.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFP09720.1 - 0.061 13.6 0.0 0.44 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFP09720.1 - 0.11 12.3 0.7 0.23 11.4 0.6 1.6 1 1 1 2 2 2 0 NTPase DUF4515 PF14988.6 KFP09721.1 - 1.7e-15 57.4 15.0 1.7e-15 57.4 15.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) YafO_toxin PF13957.6 KFP09721.1 - 0.012 15.7 3.1 0.012 15.7 3.1 2.1 2 1 0 2 2 2 0 Toxin YafO, type II toxin-antitoxin system DUF4829 PF16111.5 KFP09721.1 - 8.9 7.1 10.7 0.98 10.2 4.8 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4829) LRR_8 PF13855.6 KFP09722.1 - 2.2e-33 113.8 47.5 4.2e-08 32.8 4.4 6.3 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP09722.1 - 4.9e-29 99.9 49.1 7.6e-05 23.0 0.0 8.7 4 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP09722.1 - 2e-07 30.7 22.2 0.00011 21.8 2.1 5.0 1 1 5 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 KFP09722.1 - 0.0066 16.8 43.8 15 6.6 0.2 12.3 11 3 1 12 12 12 2 Leucine Rich Repeat H-kinase_dim PF02895.14 KFP09722.1 - 0.88 10.0 4.4 2.5 8.6 0.4 3.5 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain CSTF_C PF14304.6 KFP09722.1 - 1.3 8.7 10.7 6.8 6.4 0.1 5.1 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal Plectin PF00681.20 KFP09724.1 - 3.6e-256 826.9 7.3 2.3e-19 68.9 0.0 23.5 18 5 5 23 23 23 19 Plectin repeat HTH_10 PF04967.12 KFP09724.1 - 0.00011 22.0 0.1 22 4.9 0.0 5.6 6 0 0 6 6 6 1 HTH DNA binding domain TA0956 PF11513.8 KFP09724.1 - 0.0095 16.2 0.2 0.049 13.9 0.1 2.3 2 0 0 2 2 2 1 Thermoplasma acidophilum protein TA0956 TraD_N PF12615.8 KFP09724.1 - 0.12 13.1 0.0 0.39 11.5 0.0 1.8 1 0 0 1 1 1 0 F sex factor protein N terminal DUF4585 PF15232.6 KFP09724.1 - 0.18 11.9 7.0 2.1 8.4 0.1 5.2 4 1 0 5 5 5 0 Domain of unknown function (DUF4585) BRF1 PF07741.13 KFP09724.1 - 1 9.7 2.8 6.1 7.2 0.1 3.4 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Anoctamin PF04547.12 KFP09725.1 - 5.4e-154 513.3 20.7 6.7e-154 513.0 20.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP09725.1 - 2.9e-71 239.8 2.8 5.4e-71 238.9 2.8 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ctr PF04145.15 KFP09725.1 - 0.57 10.8 4.3 26 5.4 0.1 3.4 4 0 0 4 4 4 0 Ctr copper transporter family Halogen_Hydrol PF10112.9 KFP09725.1 - 6.3 6.8 6.5 0.83 9.6 0.2 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Homeodomain PF00046.29 KFP09726.1 - 8.8e-21 73.5 5.5 1.9e-20 72.5 5.5 1.6 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 KFP09726.1 - 0.0036 17.8 1.8 0.0076 16.7 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 KFP09726.1 - 0.036 14.0 0.3 0.036 14.0 0.3 2.1 3 0 0 3 3 3 0 Homeobox KN domain Hormone_1 PF00103.20 KFP09727.1 - 1.4e-24 87.1 1.1 1.5e-24 86.9 1.1 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Mating_N PF12731.7 KFP09727.1 - 0.042 13.9 0.4 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Mating-type protein beta 1 EGF_CA PF07645.15 KFP09728.1 - 5.1e-29 100.2 65.3 1.6e-11 44.2 6.9 10.2 8 2 1 9 9 8 5 Calcium-binding EGF domain VWC PF00093.18 KFP09728.1 - 3.4e-18 65.7 63.4 2.7e-10 40.4 14.4 10.3 6 1 1 7 7 5 4 von Willebrand factor type C domain EGF_3 PF12947.7 KFP09728.1 - 8.3e-14 51.5 38.6 1.3e-08 34.9 14.1 10.2 10 2 1 11 11 9 5 EGF domain cEGF PF12662.7 KFP09728.1 - 5.4e-10 39.0 12.3 1e-07 31.7 3.3 10.3 10 0 0 10 10 10 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFP09728.1 - 1.2e-07 32.3 0.1 2.2e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFP09728.1 - 2.2e-06 27.8 21.0 6e-05 23.2 8.4 11.0 11 1 1 12 12 8 5 EGF-like domain hEGF PF12661.7 KFP09728.1 - 3.9e-05 24.1 29.9 0.0017 18.9 5.9 12.0 12 0 0 12 12 10 5 Human growth factor-like EGF TILa PF12714.7 KFP09728.1 - 0.0001 22.2 24.0 0.00049 20.0 6.9 11.4 8 5 3 11 11 8 3 TILa domain Laminin_G_3 PF13385.6 KFP09728.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_MSP1_1 PF12946.7 KFP09728.1 - 0.00015 21.7 8.8 0.00015 21.7 8.8 8.9 9 0 0 9 9 9 3 MSP1 EGF domain 1 Laminin_G_1 PF00054.23 KFP09728.1 - 0.00023 21.4 0.0 0.00058 20.1 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain FXa_inhibition PF14670.6 KFP09728.1 - 0.017 15.4 6.4 0.017 15.4 6.4 10.5 7 2 3 10 10 9 0 Coagulation Factor Xa inhibitory site TMEM117 PF15113.6 KFP09729.1 - 4.5e-229 760.3 27.5 5.2e-229 760.1 27.5 1.0 1 0 0 1 1 1 1 TMEM117 protein family Cofilin_ADF PF00241.20 KFP09730.1 - 1.4e-43 147.5 0.1 4.4e-21 74.9 0.0 2.4 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.25 KFP09731.1 - 9e-52 176.0 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09731.1 - 3.8e-49 167.3 0.0 7e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP09731.1 - 0.0003 19.7 0.0 0.00047 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Death PF00531.22 KFP09731.1 - 0.011 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Death domain Focal_AT PF03623.13 KFP09731.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Focal adhesion targeting region TruD PF01142.18 KFP09732.1 - 5.8e-69 232.9 0.0 8.3e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) R3H PF01424.22 KFP09732.1 - 0.0025 17.8 0.2 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 R3H domain Peptidase_S28 PF05577.12 KFP09734.1 - 4.8e-101 338.7 0.1 5.6e-101 338.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 KFP09734.1 - 0.00015 22.5 0.4 0.00091 19.9 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP09734.1 - 0.00073 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP09734.1 - 0.0013 18.2 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 KFP09734.1 - 0.0018 17.0 0.0 0.004 15.9 0.0 1.5 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 KFP09734.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 KFP09734.1 - 0.02 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Rep_fac-A_C PF08646.10 KFP09735.1 - 8.1e-11 41.9 0.3 1.5e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain Ribosomal_L40e PF01020.17 KFP09735.1 - 6 6.8 7.1 1.7 8.6 3.4 1.9 2 0 0 2 2 2 0 Ribosomal L40e family Ras PF00071.22 KFP09737.1 - 2.6e-58 196.2 0.0 3.2e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09737.1 - 1.4e-37 128.5 0.0 2.7e-37 127.6 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09737.1 - 3.7e-15 55.8 0.0 4.8e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP09737.1 - 4.3e-09 36.1 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP09737.1 - 8.2e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP09737.1 - 1.4e-05 25.1 0.3 0.042 13.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KFP09737.1 - 1.5e-05 24.9 0.7 0.003 17.4 0.1 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFP09737.1 - 1.9e-05 24.3 0.0 0.00019 21.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KFP09737.1 - 0.0003 21.2 0.0 0.0016 18.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFP09737.1 - 0.00087 18.8 0.3 0.0049 16.4 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFP09737.1 - 0.00088 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KFP09737.1 - 0.0034 17.4 0.1 0.0087 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KFP09737.1 - 0.0038 17.0 0.2 0.022 14.5 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFP09737.1 - 0.0055 16.7 0.4 0.092 12.8 0.0 2.4 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFP09737.1 - 0.008 16.6 0.1 0.015 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFP09737.1 - 0.0095 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFP09737.1 - 0.01 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KFP09737.1 - 0.012 15.9 0.2 0.035 14.4 0.1 1.9 2 1 0 2 2 2 0 AAA domain TIR_2 PF13676.6 KFP09737.1 - 0.038 14.6 0.1 0.048 14.3 0.1 1.2 1 0 0 1 1 1 0 TIR domain ABC_tran PF00005.27 KFP09737.1 - 0.078 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KFP09737.1 - 0.083 12.5 0.3 13 5.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 KFP09737.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KFP09737.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP09737.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KFP09737.1 - 0.19 11.6 0.4 0.47 10.3 0.3 1.8 1 1 1 2 2 2 0 NTPase CTD_bind PF04818.13 KFP09738.1 - 1.3e-06 29.1 0.0 4.4e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SHOCT PF09851.9 KFP09738.1 - 0.0024 17.5 0.9 0.013 15.2 0.2 2.5 2 0 0 2 2 2 1 Short C-terminal domain CFIA_Pcf11 PF11526.8 KFP09738.1 - 0.0038 17.7 0.1 0.0038 17.7 0.1 5.8 4 2 0 4 4 4 1 Subunit of cleavage factor IA Pcf11 DNA_pol3_a_NI PF14480.6 KFP09738.1 - 0.079 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I EF-hand_14 PF17959.1 KFP09738.1 - 0.58 10.5 6.3 11 6.5 0.8 3.6 3 0 0 3 3 3 0 EF-hand domain Ank_2 PF12796.7 KFP09739.1 - 7.4e-45 151.4 18.3 1.2e-11 45.0 0.4 4.7 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09739.1 - 2.9e-40 136.1 25.9 3.2e-09 37.1 0.1 6.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFP09739.1 - 8.9e-24 82.9 12.2 1.2e-05 25.5 0.3 8.2 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFP09739.1 - 8.3e-23 80.2 12.0 1.3e-08 34.9 0.0 5.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP09739.1 - 1.1e-21 74.6 9.6 0.0009 19.5 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat DUF2400 PF09674.10 KFP09739.1 - 0.071 13.1 0.4 6.4 6.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) TAP42 PF04177.12 KFP09739.1 - 0.11 11.7 7.4 0.18 10.9 7.4 1.4 1 0 0 1 1 1 0 TAP42-like family Vps51 PF08700.11 KFP09739.1 - 0.16 12.1 2.0 0.54 10.4 2.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 DUF1640 PF07798.11 KFP09740.1 - 4.9e-60 202.6 16.8 7.5e-60 202.0 16.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) MHC_I_2 PF14586.6 KFP09740.1 - 0.036 13.9 0.2 0.048 13.5 0.2 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Vac_Fusion PF02346.16 KFP09740.1 - 0.064 12.9 3.7 0.17 11.6 0.1 3.2 2 2 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 JAKMIP_CC3 PF16034.5 KFP09740.1 - 0.12 12.3 8.5 0.15 12.0 8.5 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain HALZ PF02183.18 KFP09740.1 - 0.27 11.5 2.6 0.3 11.4 1.0 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2408 PF10303.9 KFP09740.1 - 0.45 11.1 9.3 1.4 9.5 8.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) IZUMO PF15005.6 KFP09740.1 - 0.79 10.2 8.0 1.3 9.6 7.3 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Caps_synth_GfcC PF06251.11 KFP09740.1 - 2.1 7.9 6.9 2 8.0 5.3 1.7 1 1 0 1 1 1 0 Capsule biosynthesis GfcC YabA PF06156.13 KFP09740.1 - 2.9 8.6 11.9 0.79 10.4 4.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA PDZ PF00595.24 KFP09742.1 - 1.4e-66 220.9 8.4 8.9e-22 77.2 0.1 3.4 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFP09742.1 - 2e-65 219.9 0.1 3.2e-65 219.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ_6 PF17820.1 KFP09742.1 - 2.5e-30 104.1 4.3 2.9e-11 43.0 0.2 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFP09742.1 - 2.9e-27 95.3 5.5 6.1e-27 94.3 5.5 1.6 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.6 KFP09742.1 - 3.6e-17 62.5 2.5 0.00013 22.2 0.0 3.7 4 0 0 4 4 4 3 PDZ domain MAGUK_N_PEST PF10608.9 KFP09742.1 - 1.8e-13 51.0 0.6 3.6e-13 50.0 0.6 1.6 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_2 PF07653.17 KFP09742.1 - 8.2e-09 35.0 0.0 2.7e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09742.1 - 9.6e-09 34.7 0.0 2.4e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP09742.1 - 0.0021 17.9 0.6 0.011 15.6 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain TMEM126 PF07114.11 KFP09754.1 - 1.7e-76 255.7 0.4 2e-76 255.4 0.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 126 GGA_N-GAT PF18308.1 KFP09754.1 - 0.084 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 GGA N-GAT domain DUF4618 PF15397.6 KFP09755.1 - 3.5e-05 23.3 15.8 4.5e-05 23.0 15.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) PRKG1_interact PF15898.5 KFP09755.1 - 0.0068 17.3 17.4 0.13 13.2 7.2 2.2 1 1 1 2 2 2 2 cGMP-dependent protein kinase interacting domain Csm1_N PF18504.1 KFP09755.1 - 0.0093 16.3 17.6 0.017 15.4 1.2 3.8 3 1 1 4 4 4 1 Csm1 N-terminal domain S_4TM PF18159.1 KFP09755.1 - 0.063 12.6 0.5 0.063 12.6 0.5 1.9 2 1 0 2 2 2 0 SMODS-associating 4TM effector domain TBCA PF02970.16 KFP09755.1 - 0.11 12.9 0.5 0.11 12.9 0.5 3.1 2 1 1 3 3 3 0 Tubulin binding cofactor A SOGA PF11365.8 KFP09755.1 - 0.11 13.6 16.9 0.14 13.3 10.0 2.5 1 1 1 2 2 2 0 Protein SOGA AcylCoA_dehyd_C PF12186.8 KFP09755.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal ApoO PF09769.9 KFP09755.1 - 0.16 11.9 2.9 0.7 9.9 0.3 2.7 1 1 1 3 3 3 0 Apolipoprotein O AA_permease_N PF08403.10 KFP09755.1 - 0.27 10.8 1.7 9.1 5.9 0.1 2.3 2 0 0 2 2 2 0 Amino acid permease N-terminal DUF4446 PF14584.6 KFP09755.1 - 0.29 11.1 11.2 1.9 8.4 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) UPF0231 PF06062.11 KFP09755.1 - 0.46 10.8 8.8 2.9 8.2 2.1 2.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Peptidase_S46 PF10459.9 KFP09755.1 - 1.4 7.5 10.1 1.7 7.2 10.1 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1515 PF07439.11 KFP09755.1 - 1.5 8.8 5.6 0.22 11.5 0.7 2.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) LPP PF04728.13 KFP09755.1 - 2.1 8.8 8.3 4.2 7.8 0.5 3.4 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF1319 PF07028.11 KFP09755.1 - 2.3 8.5 9.9 1.1 9.5 3.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) TPR_MLP1_2 PF07926.12 KFP09755.1 - 2.4 8.2 22.8 0.15 12.1 13.3 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KFP09755.1 - 2.6 8.6 23.1 8.8 6.9 11.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 KFP09755.1 - 4.3 7.4 11.3 4.3 7.4 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KFP09755.1 - 4.7 7.4 13.9 1.7 8.8 8.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 KFP09755.1 - 5 7.4 16.6 1.2 9.4 1.6 3.6 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF4200 PF13863.6 KFP09755.1 - 5.4 7.5 20.9 3.2 8.2 6.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF883 PF05957.13 KFP09755.1 - 5.9 7.6 7.8 2 9.1 0.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.11 KFP09755.1 - 8 6.9 12.2 15 6.1 0.6 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KFP09755.1 - 9.9 6.9 15.9 11 6.7 1.3 3.1 1 1 2 3 3 3 0 Initiation control protein YabA ANTH PF07651.16 KFP09756.1 - 7.8e-74 248.1 1.1 1.2e-73 247.5 1.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFP09756.1 - 6.8e-07 29.4 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 ENTH domain TauD PF02668.16 KFP09757.1 - 2.5e-40 139.0 0.2 3.4e-40 138.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFP09757.1 - 1.3e-07 32.2 0.0 4.9e-07 30.3 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFP09757.1 - 0.00089 18.5 0.0 0.0048 16.1 0.0 1.9 2 0 0 2 2 2 1 CsiD Pou PF00157.17 KFP09758.1 - 2e-27 94.9 0.0 3.9e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP09758.1 - 4.3e-18 64.9 1.7 9e-18 63.9 1.7 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KFP09758.1 - 0.0015 18.8 0.1 0.27 11.6 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KFP09758.1 - 0.033 14.1 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF4770 PF15994.5 KFP09758.1 - 0.055 13.7 0.8 0.066 13.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Lsr2 PF11774.8 KFP09758.1 - 0.19 11.9 1.1 0.3 11.2 1.1 1.3 1 1 0 1 1 1 0 Lsr2 Keratin PF02422.16 KFP09759.1 - 4e-16 58.5 10.8 4.1e-13 48.8 7.8 2.0 1 1 1 2 2 2 2 Keratin CALCOCO1 PF07888.11 KFP09759.1 - 0.43 9.4 0.5 0.51 9.2 0.5 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V-set PF07686.17 KFP09760.1 - 6.3e-12 45.6 0.0 7.5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP09760.1 - 0.00032 21.2 0.0 0.00087 19.8 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP09760.1 - 0.085 13.0 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP09760.1 - 0.098 12.7 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain Neuro_bHLH PF12533.8 KFP09762.1 - 2.7e-41 141.7 3.5 5.8e-41 140.6 3.5 1.6 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor HLH PF00010.26 KFP09762.1 - 6.6e-16 58.0 0.7 6.6e-16 58.0 0.7 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFP09762.1 - 5 5.3 7.4 6.4 4.9 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Integrin_alpha2 PF08441.12 KFP09763.1 - 3e-91 306.7 0.0 6.3e-91 305.6 0.0 1.5 2 0 0 2 2 2 1 Integrin alpha FG-GAP PF01839.23 KFP09763.1 - 3.1e-24 84.7 17.7 8.2e-11 41.8 0.0 4.9 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.6 KFP09763.1 - 1.1e-11 45.1 15.7 8.5e-09 35.9 2.2 3.4 1 1 3 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFP09763.1 - 0.00089 19.1 0.2 0.0027 17.5 0.2 1.9 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.6 KFP09763.1 - 0.0068 16.6 10.6 0.011 16.0 0.4 4.5 5 0 0 5 5 5 1 FG-GAP repeat UPF0242 PF06785.11 KFP09764.1 - 0.00065 19.9 14.9 0.00065 19.9 14.9 20.4 2 2 18 20 20 20 1 Uncharacterised protein family (UPF0242) N-terminus V-set PF07686.17 KFP09765.1 - 8.3e-12 45.2 0.3 8.3e-12 45.2 0.3 1.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFP09765.1 - 1.1e-10 41.7 1.4 1.9e-10 40.9 1.4 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFP09765.1 - 3e-05 24.6 3.1 0.022 15.4 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP09765.1 - 0.00014 21.9 3.9 0.019 15.1 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP09765.1 - 0.0061 16.9 1.5 0.88 10.0 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP09765.1 - 0.011 15.8 0.5 0.06 13.4 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin I-set domain 7tm_4 PF13853.6 KFP09766.1 - 9.7e-33 114.1 5.1 1.1e-32 113.9 5.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09766.1 - 3.3e-16 59.4 8.3 4.4e-16 59.0 8.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP09767.1 - 5.6e-38 131.3 11.5 7.1e-38 130.9 11.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09767.1 - 5.7e-22 78.3 10.8 8.2e-22 77.8 10.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP09767.1 - 0.34 10.5 8.3 1.1 8.9 8.3 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP09767.1 - 0.48 9.8 9.1 0.64 9.4 8.0 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP09768.1 - 1.4e-47 162.7 16.0 1.7e-47 162.5 16.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09768.1 - 2.2e-29 102.6 17.2 3.1e-29 102.1 17.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP09769.1 - 2.4e-44 152.2 9.3 2.8e-44 151.9 9.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09769.1 - 4.4e-30 104.9 12.6 5.9e-30 104.5 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP09769.1 - 0.0013 18.2 12.5 0.0023 17.4 10.2 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP09769.1 - 0.074 12.7 11.9 0.079 12.6 10.6 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TMEMspv1-c74-12 PF11044.8 KFP09769.1 - 0.47 10.5 3.3 4.5 7.3 4.2 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein 7tm_4 PF13853.6 KFP09770.1 - 3.8e-43 148.2 12.3 4.5e-43 148.0 12.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09770.1 - 5.9e-30 104.5 11.3 1e-29 103.7 11.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP09770.1 - 0.0011 18.7 3.3 0.0011 18.7 3.3 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP09770.1 - 0.0012 18.3 9.4 0.002 17.5 9.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TLV_coat PF00429.19 KFP09771.1 - 0.054 12.2 0.6 0.056 12.1 0.6 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Glyco_hydro_31 PF01055.26 KFP09772.1 - 1e-68 232.6 1.1 1.1e-68 232.4 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL15 PF14885.6 KFP09772.1 - 0.04 13.9 0.5 0.067 13.1 0.5 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 HU-CCDC81_euk_2 PF18289.1 KFP09773.1 - 3.5e-19 68.7 0.1 3.9e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 KFP09773.1 - 0.04 14.1 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA-binding protein CP2 PF04516.15 KFP09774.1 - 2.6e-50 170.9 0.0 4.2e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFP09774.1 - 7.1e-19 67.4 0.0 3.4e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ArsP_1 PF03773.13 KFP09774.1 - 0.045 12.9 0.0 0.099 11.8 0.0 1.5 2 0 0 2 2 2 0 Predicted permease 7tm_4 PF13853.6 KFP09775.1 - 8.2e-17 61.8 4.2 9.5e-17 61.6 4.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_4 PF13853.6 KFP09776.1 - 7.2e-44 150.6 10.5 8.5e-44 150.4 10.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09776.1 - 1.8e-29 102.9 11.4 2.8e-29 102.3 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP09776.1 - 0.0032 17.1 4.9 0.0032 17.1 4.9 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP09776.1 - 0.0053 16.2 8.6 0.0099 15.3 8.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YccF PF03733.13 KFP09776.1 - 0.045 14.5 1.6 0.045 14.5 1.6 3.2 3 1 0 3 3 3 0 Inner membrane component domain 7tm_4 PF13853.6 KFP09777.1 - 3.6e-42 145.0 15.9 4.3e-42 144.8 15.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09777.1 - 1.5e-27 96.6 14.8 2.5e-27 95.8 14.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-CCCH PF00642.24 KFP09778.1 - 1.7e-13 50.1 17.3 0.00021 21.1 0.4 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KFP09778.1 - 7.1e-06 26.2 12.1 0.012 15.8 0.8 2.7 2 1 0 2 2 2 2 Zinc-finger containing family Torus PF16131.5 KFP09778.1 - 7.4e-06 26.6 18.9 0.021 15.5 0.2 4.3 2 2 2 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 KFP09778.1 - 1.1e-05 25.7 25.3 0.36 11.4 0.8 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KFP09778.1 - 2.7e-05 23.8 2.1 2.7e-05 23.8 2.1 4.8 4 2 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP09778.1 - 0.00045 20.2 32.1 0.015 15.3 3.2 6.7 4 4 0 4 4 4 2 Zinc finger domain DUF1936 PF09151.10 KFP09778.1 - 0.34 10.9 3.8 8 6.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Glypican PF01153.19 KFP09779.1 - 3.9e-227 755.5 5.6 4.5e-227 755.3 5.6 1.0 1 0 0 1 1 1 1 Glypican DUF5082 PF16888.5 KFP09779.1 - 0.0035 17.6 0.3 0.027 14.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF1910 PF08928.10 KFP09779.1 - 0.013 15.5 0.5 0.2 11.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Fz PF01392.22 KFP09779.1 - 0.084 13.5 1.9 0.12 13.0 0.1 2.2 2 0 0 2 2 2 0 Fz domain zf-HC5HC2H PF13771.6 KFP09781.1 - 1.6e-34 118.0 31.6 6.4e-18 64.8 9.4 3.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP09781.1 - 8e-14 51.7 29.3 3.7e-07 30.3 13.1 2.9 2 2 1 3 3 3 2 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KFP09781.1 - 0.32 11.1 14.4 3.7 7.7 0.5 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pribosyltran PF00156.27 KFP09782.1 - 7.2e-15 54.9 0.0 1.2e-14 54.1 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Motile_Sperm PF00635.26 KFP09785.1 - 8.4e-18 64.2 0.2 1.4e-17 63.5 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain MMgT PF10270.9 KFP09787.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Membrane magnesium transporter LIM PF00412.22 KFP09788.1 - 5e-47 157.9 71.6 6.9e-13 48.6 10.1 5.1 5 0 0 5 5 5 5 LIM domain zf-RING_6 PF14835.6 KFP09788.1 - 0.003 17.4 2.8 0.003 17.4 2.8 5.3 4 2 1 5 5 5 2 zf-RING of BARD1-type protein Sgf11 PF08209.11 KFP09788.1 - 0.036 13.6 0.4 0.036 13.6 0.4 9.0 10 3 2 12 12 12 0 Sgf11 (transcriptional regulation protein) Ureidogly_lyase PF04115.12 KFP09788.1 - 0.13 12.1 0.2 13 5.5 0.0 2.9 1 1 1 2 2 2 0 Ureidoglycolate lyase DUF4476 PF14771.6 KFP09788.1 - 0.19 12.1 0.5 1 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) FRD2 PF03197.13 KFP09788.1 - 0.22 11.8 7.9 2.1 8.7 0.3 3.2 3 1 1 4 4 4 0 Bacteriophage FRD2 protein DUF2685 PF10886.8 KFP09788.1 - 9.7 6.5 16.0 7.5 6.8 0.1 5.4 4 2 1 5 5 5 0 Protein of unknown function (DUF2685) 7tm_2 PF00002.24 KFP09789.1 - 3e-46 157.7 23.7 4e-46 157.3 23.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP09789.1 - 6.4e-16 58.6 4.7 1.2e-15 57.7 4.7 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_1 PF00001.21 KFP09790.1 - 4.4e-58 196.7 14.9 6.5e-58 196.1 14.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP09790.1 - 1.7e-11 44.0 14.3 2.6e-11 43.4 14.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP09790.1 - 1.1e-08 34.8 14.5 1.4e-08 34.4 14.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP09790.1 - 1.5e-06 28.0 10.2 1.5e-06 28.0 10.2 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 KFP09790.1 - 0.00063 18.9 3.6 0.00063 18.9 3.6 2.0 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) Gaa1 PF04114.14 KFP09790.1 - 1.8 7.5 9.9 0.32 10.0 1.9 2.0 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component RRM_1 PF00076.22 KFP09791.1 - 5.2e-16 58.2 0.0 8.6e-07 28.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP09791.1 - 0.01 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KFP09791.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1998 PF09369.10 KFP09791.1 - 0.15 12.9 0.0 1.5 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1998) Vg_Tdu PF07545.14 KFP09792.1 - 9.2e-20 70.1 0.3 1.7e-19 69.2 0.3 1.5 1 0 0 1 1 1 1 Vestigial/Tondu family TNF PF00229.18 KFP09793.1 - 3e-30 104.8 0.6 5.1e-30 104.0 0.2 1.6 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 KFP09793.1 - 0.0013 19.0 1.0 0.0051 17.0 0.3 2.4 2 1 0 2 2 2 1 C1q domain Neur_chan_memb PF02932.16 KFP09793.1 - 0.028 14.5 0.3 0.036 14.1 0.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2244 PF10003.9 KFP09793.1 - 0.11 12.1 0.1 0.32 10.7 0.1 1.7 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) RhoGEF67_u2 PF16614.5 KFP09794.1 - 3.4e-55 184.7 1.0 3.4e-55 184.7 1.0 2.4 2 0 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 betaPIX_CC PF16523.5 KFP09794.1 - 8.6e-37 124.9 9.6 8.6e-37 124.9 9.6 3.3 4 0 0 4 4 4 1 betaPIX coiled coil RhoGEF PF00621.20 KFP09794.1 - 2.5e-32 112.6 1.3 2.5e-32 112.6 1.3 2.2 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 KFP09794.1 - 2e-17 62.7 0.1 4.3e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 KFP09794.1 - 1.6e-16 60.5 0.1 4.2e-16 59.1 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain SH3_2 PF07653.17 KFP09794.1 - 2.7e-16 59.0 0.4 5.3e-16 58.1 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09794.1 - 1.7e-14 53.2 0.3 3.1e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFP09794.1 - 3.6e-10 40.3 0.0 8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 PH domain RhoGEF67_u1 PF16615.5 KFP09794.1 - 1.4e-09 38.3 4.7 1.4e-09 38.3 4.7 2.4 2 0 0 2 2 2 1 Unstructured region one on RhoGEF 6 and 7 CAMSAP_CH PF11971.8 KFP09794.1 - 0.00074 19.3 0.1 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Nmad5 PF18757.1 KFP09794.1 - 0.51 10.5 5.0 0.8 9.9 2.8 2.5 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 She9_MDM33 PF05546.11 KFP09794.1 - 0.88 9.3 6.7 8.7 6.1 1.6 2.5 2 0 0 2 2 2 0 She9 / Mdm33 family CENP-Q PF13094.6 KFP09794.1 - 1 9.5 19.1 0.028 14.6 5.9 3.4 4 0 0 4 4 3 0 CENP-Q, a CENPA-CAD centromere complex subunit RPW8 PF05659.11 KFP09794.1 - 1.1 8.9 11.1 1.2 8.8 0.6 2.9 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4559 PF15112.6 KFP09794.1 - 1.6 8.3 8.3 0.67 9.6 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4559) ZapB PF06005.12 KFP09794.1 - 1.8 9.1 17.8 0.12 12.8 5.9 3.6 3 0 0 3 3 3 0 Cell division protein ZapB SKA1 PF07160.12 KFP09794.1 - 2.2 8.0 10.9 0.18 11.6 2.9 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 kleA_kleC PF17383.2 KFP09794.1 - 3.4 8.1 5.3 1.8 9.0 0.6 2.7 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF724 PF05266.14 KFP09794.1 - 5 6.9 11.2 3.1 7.6 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF745 PF05335.13 KFP09794.1 - 8.5 6.1 8.8 0.58 9.9 0.5 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF745) Nsp1_C PF05064.13 KFP09794.1 - 9.9 6.0 11.7 0.32 10.8 1.7 3.3 4 1 0 4 4 3 0 Nsp1-like C-terminal region RRM_1 PF00076.22 KFP09795.1 - 3.9e-23 81.0 0.1 5.8e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.11 KFP09795.1 - 3.4e-21 75.0 18.8 3.4e-21 75.0 18.8 9.8 6 1 1 7 7 7 1 RBM1CTR (NUC064) family RRM_7 PF16367.5 KFP09795.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 KFP09795.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP09795.1 - 0.062 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFP09795.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter EMP70 PF02990.16 KFP09796.1 - 2e-216 719.7 11.8 2.5e-216 719.4 11.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 zf_ZIC PF18366.1 KFP09797.1 - 3.7e-27 94.1 0.5 3.7e-27 94.1 0.5 3.8 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFP09797.1 - 1.4e-22 78.8 31.6 2.4e-06 27.7 3.0 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP09797.1 - 2.1e-14 53.2 19.1 7e-07 29.4 0.3 6.3 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP09797.1 - 5e-08 33.0 13.6 0.0046 17.2 0.2 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP09797.1 - 6e-07 29.8 50.0 0.0011 19.7 1.9 6.4 6 0 0 6 6 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP09797.1 - 0.00012 22.3 12.9 0.00019 21.7 1.0 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP09797.1 - 0.00046 20.1 14.0 0.00087 19.2 1.8 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP09797.1 - 0.0022 18.2 13.2 0.042 14.1 2.1 3.3 1 1 2 3 3 3 3 C2H2-type zinc ribbon Zf_RING PF16744.5 KFP09797.1 - 0.065 13.4 0.8 0.22 11.7 0.1 2.1 1 1 0 2 2 2 0 KIAA1045 RING finger CH_2 PF06294.11 KFP09797.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 CH-like domain in sperm protein MGC-24 PF05283.11 KFP09797.1 - 1.3 9.5 4.4 13 6.3 0.0 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FGF PF00167.18 KFP09799.1 - 6.4e-44 149.0 0.4 8.2e-44 148.7 0.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP09799.1 - 0.00018 21.7 0.1 0.0017 18.6 0.0 2.0 1 1 1 2 2 2 1 Fascin domain TGF_beta_GS PF08515.12 KFP09799.1 - 0.096 12.2 0.5 0.2 11.2 0.5 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif RhoGEF PF00621.20 KFP09800.1 - 2.9e-39 135.2 0.9 2.9e-39 135.2 0.9 2.8 3 0 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.6 KFP09800.1 - 3.8e-07 30.3 0.0 1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.29 KFP09800.1 - 1.2e-06 29.0 0.2 3.1e-06 27.6 0.2 1.8 1 0 0 1 1 1 1 PH domain Spectrin PF00435.21 KFP09800.1 - 0.0079 16.7 1.2 0.0079 16.7 1.2 4.6 5 0 0 5 5 5 2 Spectrin repeat Lzipper-MIP1 PF14389.6 KFP09800.1 - 0.035 14.4 0.4 0.41 11.0 1.2 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PH_10 PF15411.6 KFP09800.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PhoLip_ATPase_C PF16212.5 KFP09801.1 - 1.3e-73 247.8 32.9 1.3e-73 247.8 32.9 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP09801.1 - 6.8e-23 80.1 0.6 6.8e-23 80.1 0.6 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KFP09801.1 - 4.8e-11 42.5 0.0 4.8e-11 42.5 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP09801.1 - 2.2e-10 40.5 0.1 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP09801.1 - 6.9e-09 36.3 2.5 9.3e-06 26.1 2.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF63 PF01889.17 KFP09801.1 - 0.0056 16.9 5.8 0.015 15.5 5.8 1.7 1 0 0 1 1 1 1 Membrane protein of unknown function DUF63 Hydrolase_3 PF08282.12 KFP09801.1 - 0.0074 16.0 0.5 0.5 10.1 0.0 3.2 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase VPS13_mid_rpt PF16910.5 KFP09801.1 - 0.13 11.7 0.3 0.25 10.7 0.3 1.4 1 0 0 1 1 1 0 Repeating coiled region of VPS13 NAD_binding_6 PF08030.12 KFP09802.1 - 8.7e-31 107.2 0.0 1.8e-30 106.1 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFP09802.1 - 1.5e-22 79.8 0.0 2.6e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KFP09802.1 - 5.5e-11 42.7 1.8 5.5e-11 42.7 1.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KFP09802.1 - 0.0022 18.3 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFP09802.1 - 0.01 16.4 0.0 0.049 14.3 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Dpoe2NT PF12213.8 KFP09802.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal CSTF2_hinge PF14327.6 KFP09803.1 - 4.6e-30 103.9 2.9 9.8e-30 102.9 2.9 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KFP09803.1 - 4.6e-18 64.5 12.9 7.5e-18 63.8 9.9 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 KFP09803.1 - 3.7e-10 39.5 0.0 6.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Met_10 PF02475.16 KFP09804.1 - 2e-28 99.5 0.0 2.6e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFP09804.1 - 0.00075 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.11 KFP09804.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Cons_hypoth95 PF03602.15 KFP09804.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Tetraspanin PF00335.20 KFP09805.1 - 2e-29 102.9 4.5 2.3e-29 102.8 4.5 1.0 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.11 KFP09805.1 - 0.01 15.8 0.3 0.018 15.0 0.3 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF4190 PF13828.6 KFP09805.1 - 0.066 13.0 3.5 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) FeoB_C PF07664.12 KFP09805.1 - 1.4 8.7 4.2 0.44 10.3 0.3 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus BRICHOS PF04089.14 KFP09806.1 - 2.2e-16 59.9 0.0 4.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 BRICHOS domain Cadherin PF00028.17 KFP09813.1 - 1.1e-113 371.9 5.6 2.5e-22 79.1 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.11 KFP09813.1 - 3.2e-85 285.5 3.5 5.1e-85 284.9 3.5 1.3 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.12 KFP09813.1 - 6.3e-20 70.8 0.1 1.2e-08 34.7 0.0 5.2 5 0 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 KFP09813.1 - 1.3e-09 38.1 11.4 0.0076 16.2 0.1 5.8 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 KFP09813.1 - 0.003 18.2 38.0 0.023 15.3 0.6 6.0 7 0 0 7 7 6 3 Bacterial cadherin-like domain Big_9 PF17963.1 KFP09813.1 - 0.0095 16.7 28.6 0.98 10.2 1.1 5.5 5 0 0 5 5 5 3 Bacterial Ig domain RET_CLD1 PF17756.1 KFP09813.1 - 0.013 15.8 0.0 1.8 8.9 0.0 2.9 2 0 0 2 2 2 0 RET Cadherin like domain 1 TMEM154 PF15102.6 KFP09813.1 - 0.014 15.3 0.3 0.043 13.7 0.3 1.8 1 0 0 1 1 1 0 TMEM154 protein family Y_Y_Y PF07495.13 KFP09813.1 - 0.021 14.8 0.0 0.57 10.2 0.0 3.4 3 0 0 3 3 3 0 Y_Y_Y domain AP3D1 PF06375.11 KFP09813.1 - 0.026 14.8 0.9 0.062 13.5 0.9 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 EphA2_TM PF14575.6 KFP09813.1 - 0.12 13.2 0.2 0.52 11.2 0.2 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KFP09813.1 - 0.13 13.0 0.1 1.2 9.9 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal He_PIG PF05345.12 KFP09813.1 - 0.94 9.7 9.2 3.7 7.8 0.1 5.0 5 1 0 5 5 4 0 Putative Ig domain DUF4462 PF14692.6 KFP09819.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Kelch_1 PF01344.25 KFP09820.1 - 3.1e-75 247.5 22.9 7.1e-15 54.3 0.1 6.5 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFP09820.1 - 1.7e-48 161.4 7.2 1e-09 38.3 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFP09820.1 - 1.4e-32 111.9 2.2 1.9e-32 111.5 0.0 2.4 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 KFP09820.1 - 3.9e-31 107.6 1.7 6.5e-31 106.8 0.9 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP09820.1 - 9.3e-25 85.6 7.4 3.9e-06 26.6 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KFP09820.1 - 4.8e-22 77.7 11.2 0.00029 20.8 0.1 6.3 3 1 3 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP09820.1 - 2.2e-16 59.7 11.2 0.023 15.0 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP09820.1 - 3.6e-05 23.6 6.6 0.5 10.4 0.0 5.9 6 0 0 6 6 6 1 Kelch motif DUF3342 PF11822.8 KFP09820.1 - 0.022 15.0 0.4 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) Hydrolase PF00702.26 KFP09820.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DDE_Tnp_1_6 PF13751.6 KFP09821.1 - 0.32 11.2 5.2 0.63 10.3 5.2 1.4 1 0 0 1 1 1 0 Transposase DDE domain LMBR1 PF04791.16 KFP09821.1 - 0.36 9.7 1.9 0.43 9.4 1.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4778 PF16008.5 KFP09821.1 - 1.4 8.9 9.4 3.1 7.8 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) GDI PF00996.18 KFP09822.1 - 1.8e-54 185.0 0.1 7.7e-47 159.8 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KFP09822.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ATG16 PF08614.11 KFP09823.1 - 0.0014 18.9 27.8 0.065 13.4 8.3 2.6 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KFP09823.1 - 0.012 16.2 12.7 0.012 16.2 12.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Flavi_glycop_C PF02832.16 KFP09823.1 - 0.024 14.8 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Angiomotin_C PF12240.8 KFP09823.1 - 0.68 9.5 19.9 77 2.7 19.9 3.2 1 1 0 1 1 1 0 Angiomotin C terminal Spc7 PF08317.11 KFP09823.1 - 2.6 6.9 23.2 3.5 6.4 9.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KFP09823.1 - 3.5 7.1 25.0 3.7 7.0 8.7 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 PKcGMP_CC PF16808.5 KFP09823.1 - 9.9 6.1 15.7 0.52 10.2 0.4 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Zfx_Zfy_act PF04704.13 KFP09824.1 - 6.5e-154 511.9 15.6 6.5e-154 511.9 15.6 1.8 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-C2H2 PF00096.26 KFP09824.1 - 1.1e-40 135.8 116.6 2.6e-06 27.6 2.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP09824.1 - 5.2e-35 118.3 119.4 1.1e-05 25.6 2.6 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP09824.1 - 1.3e-31 106.5 110.8 0.0001 22.8 2.3 12.4 12 0 0 12 12 12 12 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP09824.1 - 1.2e-25 88.9 104.8 3.6e-07 29.8 0.9 12.4 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP09824.1 - 5.7e-10 39.2 82.1 0.016 15.5 0.1 11.9 12 0 0 12 12 12 6 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFP09824.1 - 2.4e-07 31.4 48.1 0.012 16.3 2.7 7.1 4 2 3 7 7 7 4 zinc-ribbon family zf-C2H2_6 PF13912.6 KFP09824.1 - 0.0081 16.1 11.4 0.012 15.7 3.9 8.4 8 0 0 8 8 7 3 C2H2-type zinc finger zf-met PF12874.7 KFP09824.1 - 0.028 14.8 71.7 0.068 13.6 0.1 10.9 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP09824.1 - 0.044 13.6 0.5 0.044 13.6 0.5 10.3 11 0 0 11 11 11 0 zinc-finger C2H2-type Ribosomal_S17e PF00833.18 KFP09824.1 - 0.086 12.8 0.6 0.22 11.5 0.6 1.6 1 0 0 1 1 1 0 Ribosomal S17 HypA PF01155.19 KFP09824.1 - 9.3 6.3 38.6 1.1 9.3 2.9 6.3 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ApoO PF09769.9 KFP09825.1 - 1.5e-37 128.5 0.0 2.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O DUF2214 PF09980.9 KFP09825.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) DUF1170 PF06663.13 KFP09826.1 - 7.4e-57 192.5 7.5 2.4e-56 190.8 5.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFP09826.1 - 7.4e-38 128.6 1.1 1.9e-37 127.3 0.2 2.2 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras PH PF00169.29 KFP09826.1 - 5.7e-15 55.7 2.9 1.4e-14 54.4 2.9 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 KFP09826.1 - 8.2e-15 55.0 0.3 2.6e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFP09826.1 - 1.2e-09 38.3 0.0 1.3e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 KFP09826.1 - 1.8e-09 37.5 0.6 5.7e-09 36.0 0.6 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFP09826.1 - 1.9e-08 34.0 0.1 4.8e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP09826.1 - 0.0032 17.7 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFP09826.1 - 0.06 13.8 10.8 0.66 10.4 10.8 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 KFP09826.1 - 0.078 13.4 1.8 2.9 8.3 1.1 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Phage-MuB_C PF09077.11 KFP09826.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Mu B transposition protein, C terminal Homeodomain PF00046.29 KFP09827.1 - 1.7e-11 43.8 2.2 5e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Homeodomain THEG4 PF15834.5 KFP09827.1 - 3.3 7.7 7.6 3.1 7.8 0.2 2.7 3 0 0 3 3 3 0 Testis highly expressed protein 4 Pkinase PF00069.25 KFP09828.1 - 2.2e-145 482.9 0.0 1.3e-72 244.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09828.1 - 9.5e-75 251.2 0.0 6.9e-40 137.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP09828.1 - 7.7e-13 48.4 0.0 3.5e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFP09828.1 - 2.6e-10 40.0 0.0 1.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP09828.1 - 2.7e-08 33.0 0.0 0.00097 18.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 KFP09828.1 - 3.2e-07 29.7 0.3 0.0027 16.7 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 KFP09828.1 - 3.4e-06 27.7 1.5 9.7e-06 26.2 1.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KFP09828.1 - 2.7e-05 24.2 0.1 0.24 11.3 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFP09828.1 - 0.00021 20.9 0.0 0.08 12.5 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFP09828.1 - 0.00063 19.4 0.1 2.1 7.9 0.0 3.2 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFP09828.1 - 0.015 14.9 0.0 0.61 9.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KFP09828.1 - 0.13 11.2 0.1 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KFP09828.1 - 0.18 11.3 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Peptidase_M24 PF00557.24 KFP09829.1 - 5e-21 75.4 0.2 5.8e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-H2C2_2 PF13465.6 KFP09830.1 - 7.5e-59 193.7 50.8 4.8e-11 42.6 0.7 6.8 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP09830.1 - 4.7e-46 152.7 61.6 1.3e-08 34.8 2.2 7.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP09830.1 - 1.6e-31 106.3 55.7 2.9e-06 27.6 1.4 6.4 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP09830.1 - 2.5e-16 59.5 34.6 0.00064 19.9 0.5 6.2 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP09830.1 - 4.3e-15 55.2 32.4 0.00032 20.5 0.7 6.7 7 0 0 7 7 6 5 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFP09830.1 - 2.6e-13 49.6 50.7 3e-06 27.1 1.8 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf_UBZ PF18439.1 KFP09830.1 - 2.5e-12 46.1 26.4 0.027 14.1 0.1 6.2 6 0 0 6 6 6 5 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP09830.1 - 1.2e-11 44.5 25.2 8e-05 22.7 2.3 4.4 2 1 3 5 5 5 5 Zinc ribbon domain zf-Di19 PF05605.12 KFP09830.1 - 5.8e-11 42.5 34.7 0.013 15.8 0.4 5.4 1 1 3 5 5 5 5 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.6 KFP09830.1 - 2.4e-10 40.5 23.6 0.11 12.5 0.2 6.0 4 1 2 6 6 6 3 CpXC protein FYDLN_acid PF09538.10 KFP09830.1 - 2.1e-08 34.8 17.9 0.65 10.7 1.3 6.0 1 1 4 5 5 5 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.6 KFP09830.1 - 4.1e-08 33.3 20.5 1.1 9.5 0.1 6.0 6 0 0 6 6 6 3 zinc-ribbon zf-AN1 PF01428.16 KFP09830.1 - 9.1e-08 32.1 27.7 1.3 9.2 0.2 6.2 5 1 1 6 6 6 1 AN1-like Zinc finger Zn_ribbon_SprT PF17283.2 KFP09830.1 - 1.3e-06 28.2 29.7 0.49 10.3 6.8 5.8 4 2 0 4 4 4 3 SprT-like zinc ribbon domain zinc_ribbon_5 PF13719.6 KFP09830.1 - 2.6e-06 27.1 23.0 1 9.2 0.1 5.9 6 0 0 6 6 6 3 zinc-ribbon domain DUF3268 PF11672.8 KFP09830.1 - 2.6e-06 27.7 15.6 0.027 14.8 0.9 3.8 1 1 4 5 5 5 5 zinc-finger-containing domain zf-ribbon_3 PF13248.6 KFP09830.1 - 4.5e-06 25.9 25.8 0.26 10.8 0.3 6.2 6 0 0 6 6 6 3 zinc-ribbon domain zf-met PF12874.7 KFP09830.1 - 4.9e-06 26.7 44.4 0.48 10.9 1.4 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 KFP09830.1 - 6.6e-06 26.0 34.9 0.039 13.9 3.2 4.3 2 1 2 4 4 4 4 Transposase zinc-ribbon domain YacG PF03884.14 KFP09830.1 - 6.7e-06 25.7 16.8 2.7 7.8 0.1 6.1 6 0 0 6 6 6 0 DNA gyrase inhibitor YacG zinc_ribbon_15 PF17032.5 KFP09830.1 - 1.2e-05 25.9 20.7 0.059 14.1 1.4 3.5 1 1 4 5 5 5 5 zinc-ribbon family DZR PF12773.7 KFP09830.1 - 1.4e-05 25.0 28.1 7.1e+03 -2.9 28.1 3.9 1 1 0 1 1 0 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KFP09830.1 - 1.4e-05 24.9 24.7 1.9 8.5 0.1 6.0 6 0 0 6 6 6 2 zinc-ribbon domain Cys_rich_CPXG PF14255.6 KFP09830.1 - 1.5e-05 24.8 20.6 0.63 10.0 0.1 5.8 6 0 0 6 6 6 2 Cysteine-rich CPXCG zinc_ribbon_10 PF10058.9 KFP09830.1 - 0.00013 21.6 16.5 5.9 6.7 0.1 6.0 6 0 0 6 6 6 0 Predicted integral membrane zinc-ribbon metal-binding protein YhfH PF14149.6 KFP09830.1 - 0.00013 21.9 17.4 3 7.9 0.1 6.0 6 0 0 6 6 6 0 YhfH-like protein zf-BED PF02892.15 KFP09830.1 - 0.00015 21.7 33.0 0.32 11.1 1.7 6.1 1 1 5 6 6 6 2 BED zinc finger zf-RING_7 PF02591.15 KFP09830.1 - 0.00017 21.7 19.5 2.4 8.4 0.2 5.8 6 0 0 6 6 6 0 C4-type zinc ribbon domain zf-C2H2_11 PF16622.5 KFP09830.1 - 0.00042 20.0 32.4 0.16 11.8 0.5 6.2 6 0 0 6 6 6 3 zinc-finger C2H2-type Ogr_Delta PF04606.12 KFP09830.1 - 0.00061 19.7 27.8 0.032 14.2 2.0 4.7 4 1 0 4 4 4 2 Ogr/Delta-like zinc finger HypA PF01155.19 KFP09830.1 - 0.00063 19.7 20.8 0.081 12.9 1.0 4.0 1 1 2 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KFP09830.1 - 0.0011 18.9 25.9 3.6 7.7 5.9 5.0 1 1 2 3 3 3 0 zinc-ribbons TerY_C PF15616.6 KFP09830.1 - 0.0011 19.1 15.3 0.13 12.4 1.9 3.3 1 1 2 3 3 3 2 TerY-C metal binding domain PyrI_C PF02748.15 KFP09830.1 - 0.0014 18.4 18.4 8.6 6.4 0.5 6.0 6 0 0 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 KFP09830.1 - 0.0025 17.6 20.6 0.21 11.4 0.4 5.0 2 1 3 5 5 5 1 GAGA factor XPA_N PF01286.18 KFP09830.1 - 0.0027 17.7 26.2 7.1 6.8 0.2 6.1 6 0 0 6 6 6 0 XPA protein N-terminal TF_Zn_Ribbon PF08271.12 KFP09830.1 - 0.0043 16.5 19.3 4.1 7.0 0.1 6.0 6 0 0 6 6 6 0 TFIIB zinc-binding CxC7 PF18866.1 KFP09830.1 - 0.0053 16.9 23.8 3 8.1 0.1 6.0 1 1 4 6 6 6 0 CxC7 like cysteine cluster associated with KDZ transposases zf-C2HE PF16278.5 KFP09830.1 - 0.0059 17.0 32.2 12 6.5 0.6 6.1 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-HIT PF04438.16 KFP09830.1 - 0.0066 16.3 28.2 1.2 9.1 0.3 6.2 6 0 0 6 6 6 1 HIT zinc finger zf-trcl PF13451.6 KFP09830.1 - 0.0075 16.1 20.1 0.42 10.6 1.6 5.8 5 1 1 6 6 6 1 Probable zinc-ribbon domain Thioredoxin_4 PF13462.6 KFP09830.1 - 0.017 15.3 16.2 2.2 8.4 0.0 5.0 4 1 1 5 5 5 0 Thioredoxin DUF2256 PF10013.9 KFP09830.1 - 0.019 15.1 16.6 33 4.7 0.1 6.0 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KFP09830.1 - 0.027 14.5 18.2 0.53 10.3 1.0 5.2 3 2 2 5 5 5 0 Adenylate kinase, active site lid Zn-C2H2_12 PF18112.1 KFP09830.1 - 0.028 14.9 30.2 1.3 9.5 0.1 6.1 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain HalOD2 PF18547.1 KFP09830.1 - 0.046 13.6 0.9 0.046 13.6 0.9 4.8 2 2 2 4 4 3 0 Halobacterial output domain 2 MBD PF01429.19 KFP09830.1 - 0.052 13.3 6.6 8.6 6.2 3.8 3.8 1 1 1 2 2 2 0 Methyl-CpG binding domain PHF5 PF03660.14 KFP09830.1 - 0.052 13.7 10.8 0.81 9.9 1.0 2.7 1 1 2 3 3 3 0 PHF5-like protein zf-Mss51 PF13824.6 KFP09830.1 - 0.079 13.1 40.1 0.93 9.6 1.3 5.9 1 1 5 6 6 6 0 Zinc-finger of mitochondrial splicing suppressor 51 Terminase_GpA PF05876.12 KFP09830.1 - 0.079 11.5 21.4 0.041 12.4 2.1 3.1 1 1 3 4 4 4 0 Phage terminase large subunit (GpA) Rad50_zn_hook PF04423.14 KFP09830.1 - 0.085 12.7 15.3 12 5.8 0.2 5.4 4 1 1 5 5 5 0 Rad50 zinc hook motif DUF4379 PF14311.6 KFP09830.1 - 0.14 12.6 25.8 0.91 9.9 2.4 4.4 2 2 2 4 4 4 0 Probable Zinc-ribbon domain C1_4 PF07975.12 KFP09830.1 - 0.14 12.4 29.3 3.7 7.8 3.0 5.2 1 1 4 6 6 5 0 TFIIH C1-like domain zf-Paramyx-P PF13008.7 KFP09830.1 - 0.14 11.6 23.9 6.8 6.2 0.2 6.1 6 0 0 6 6 6 0 Zinc-binding domain of Paramyxoviridae V protein HscB_4_cys PF18256.1 KFP09830.1 - 0.15 11.9 22.4 11 5.9 0.2 5.9 6 0 0 6 6 6 0 Co-chaperone HscB tetracysteine metal binding motif DNA_RNApol_7kD PF03604.13 KFP09830.1 - 0.15 11.7 18.3 7.5 6.3 0.4 5.9 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-DNA_Pol PF08996.10 KFP09830.1 - 0.16 11.7 21.6 0.17 11.6 0.6 3.5 1 1 4 5 5 5 0 DNA Polymerase alpha zinc finger DUF2757 PF10955.8 KFP09830.1 - 0.19 12.0 20.4 16 5.8 0.1 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF2757) PHD PF00628.29 KFP09830.1 - 0.2 11.6 30.5 0.68 9.9 8.5 4.3 1 1 3 5 5 5 0 PHD-finger Zn_ribbon_recom PF13408.6 KFP09830.1 - 0.31 11.6 22.0 46 4.6 7.0 4.7 1 1 3 4 4 4 0 Recombinase zinc beta ribbon domain TFIIS_C PF01096.18 KFP09830.1 - 0.4 10.6 25.4 8.1 6.4 0.1 6.1 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-MYST PF17772.1 KFP09830.1 - 0.48 10.1 15.4 19 5.0 0.1 5.3 2 1 4 6 6 6 0 MYST family zinc finger domain LIM PF00412.22 KFP09830.1 - 0.88 9.8 25.1 3.6 7.9 2.0 5.2 1 1 4 5 5 5 0 LIM domain IBR PF01485.21 KFP09830.1 - 1 9.6 30.6 18 5.7 7.1 4.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-H2C2_5 PF13909.6 KFP09830.1 - 1.2 9.0 68.3 0.18 11.6 1.4 8.6 7 2 0 7 7 6 0 C2H2-type zinc-finger domain Zf_RING PF16744.5 KFP09830.1 - 1.2 9.3 17.9 18 5.5 0.9 5.4 1 1 5 6 6 5 0 KIAA1045 RING finger zf-LYAR PF08790.11 KFP09830.1 - 1.4 8.9 27.0 0.92 9.5 0.5 6.1 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zf-RING_5 PF14634.6 KFP09830.1 - 1.7 8.7 31.3 2.8 8.0 0.9 5.8 3 2 2 5 5 5 0 zinc-RING finger domain DUF3797 PF12677.7 KFP09830.1 - 2.1 8.3 18.8 22 5.0 0.0 5.7 5 1 1 6 6 6 0 Domain of unknown function (DUF3797) zf-FPG_IleRS PF06827.14 KFP09830.1 - 3.1 7.8 20.9 27 4.7 0.0 5.5 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS zf-C2H2_9 PF16293.5 KFP09830.1 - 3.6 7.5 16.5 15 5.5 0.0 4.9 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) Desulfoferrod_N PF06397.12 KFP09830.1 - 3.9 7.2 21.0 21 4.9 0.1 5.7 6 0 0 6 6 6 0 Desulfoferrodoxin, N-terminal domain Baculo_IE-1 PF05290.11 KFP09830.1 - 4.7 7.2 21.2 21 5.0 0.2 5.3 4 1 0 4 4 4 0 Baculovirus immediate-early protein (IE-0) DUF35_N PF12172.8 KFP09830.1 - 4.8 7.2 26.6 6.1 6.8 0.2 6.1 6 0 0 6 6 6 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cys_rich_CWC PF14375.6 KFP09830.1 - 5.1 7.6 14.8 67 4.0 0.1 5.4 5 1 0 6 6 5 0 Cysteine-rich CWC zf-IS66 PF13005.7 KFP09830.1 - 6.1 7.3 29.7 27 5.3 0.3 6.3 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 DUF983 PF06170.12 KFP09830.1 - 7.1 7.1 20.8 38 4.8 0.1 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF983) zf-ISL3 PF14690.6 KFP09830.1 - 8.2 7.2 28.2 13 6.6 0.1 6.3 5 1 0 5 5 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.6 KFP09830.1 - 9.9 6.0 36.7 4 7.3 0.8 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 KFP09831.1 - 2.1e-28 97.4 37.5 1.5e-11 44.2 0.9 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP09831.1 - 1e-27 95.0 34.9 8.5e-08 32.2 3.0 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP09831.1 - 9.3e-20 69.6 31.9 9.9e-06 26.0 2.5 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP09831.1 - 4e-11 42.5 18.5 0.0033 17.3 0.2 4.6 4 1 0 4 4 4 4 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFP09831.1 - 1.3e-10 41.3 14.7 0.029 14.7 0.4 4.2 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP09831.1 - 6.6e-10 39.1 19.8 0.00039 20.7 7.5 3.8 1 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KFP09831.1 - 1.6e-08 34.5 11.5 1.4e-05 25.1 2.0 2.7 1 1 2 3 3 3 3 Zinc ribbon domain CpXC PF14353.6 KFP09831.1 - 1.2e-07 31.7 9.5 0.43 10.6 1.7 4.0 1 1 2 3 3 3 3 CpXC protein zinc_ribbon_5 PF13719.6 KFP09831.1 - 5.1e-07 29.3 10.0 0.45 10.3 0.2 4.1 4 0 0 4 4 4 2 zinc-ribbon domain Cys_rich_CPXG PF14255.6 KFP09831.1 - 9.3e-07 28.7 9.4 0.24 11.3 0.1 4.2 4 0 0 4 4 4 2 Cysteine-rich CPXCG zf_UBZ PF18439.1 KFP09831.1 - 4.4e-06 26.2 14.8 0.36 10.5 0.1 4.2 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger Prok-RING_1 PF14446.6 KFP09831.1 - 5e-06 26.4 9.1 0.035 14.0 1.5 4.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.6 KFP09831.1 - 5.6e-06 26.2 28.5 0.1 12.6 1.5 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-BED PF02892.15 KFP09831.1 - 1.4e-05 25.0 13.5 0.16 12.1 1.1 4.1 1 1 3 4 4 4 2 BED zinc finger zinc_ribbon_4 PF13717.6 KFP09831.1 - 1.4e-05 24.9 14.3 0.85 9.6 5.0 4.0 3 1 0 3 3 3 2 zinc-ribbon domain FYDLN_acid PF09538.10 KFP09831.1 - 1.6e-05 25.5 8.2 1 10.1 0.1 4.0 1 1 3 4 4 4 1 Protein of unknown function (FYDLN_acid) Zn-C2H2_12 PF18112.1 KFP09831.1 - 1.9e-05 25.0 12.5 1.6 9.2 0.0 4.3 4 0 0 4 4 4 1 Autophagy receptor zinc finger-C2H2 domain YacG PF03884.14 KFP09831.1 - 2.5e-05 23.9 8.6 3.3 7.5 0.1 4.2 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG zinc_ribbon_15 PF17032.5 KFP09831.1 - 2.6e-05 24.9 6.8 0.012 16.3 0.6 2.1 1 1 1 2 2 2 2 zinc-ribbon family GAGA PF09237.11 KFP09831.1 - 4e-05 23.3 7.4 0.86 9.5 0.2 3.7 1 1 2 3 3 3 3 GAGA factor DZR PF12773.7 KFP09831.1 - 4.1e-05 23.5 12.3 0.053 13.6 12.3 2.5 1 1 0 1 1 1 1 Double zinc ribbon DUF3268 PF11672.8 KFP09831.1 - 4.2e-05 23.8 2.4 0.03 14.7 0.3 2.1 2 0 0 2 2 2 2 zinc-finger-containing domain zinc_ribbon_9 PF14369.6 KFP09831.1 - 4.6e-05 23.6 18.4 0.82 10.0 0.4 4.2 4 0 0 4 4 4 3 zinc-ribbon zf-AN1 PF01428.16 KFP09831.1 - 7.6e-05 22.8 15.9 0.33 11.1 0.3 4.1 4 0 0 4 4 4 3 AN1-like Zinc finger zf-met PF12874.7 KFP09831.1 - 0.00011 22.5 21.1 0.28 11.6 0.8 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zinc-ribbons_6 PF07191.12 KFP09831.1 - 0.00015 21.7 11.4 0.18 11.8 1.7 3.3 1 1 1 2 2 2 1 zinc-ribbons Terminase_GpA PF05876.12 KFP09831.1 - 0.00015 20.5 9.8 0.017 13.7 2.2 2.0 1 1 0 2 2 2 2 Phage terminase large subunit (GpA) zinc_ribbon_10 PF10058.9 KFP09831.1 - 0.00018 21.1 8.9 0.98 9.2 0.1 3.4 3 1 0 3 3 3 2 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 KFP09831.1 - 0.00021 20.6 16.0 0.29 10.6 0.4 4.2 4 0 0 4 4 4 2 zinc-ribbon domain HypA PF01155.19 KFP09831.1 - 0.00061 19.8 6.2 0.021 14.8 0.7 2.3 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 KFP09831.1 - 0.00062 19.6 19.1 0.18 11.8 7.5 4.1 2 1 1 3 3 3 2 SprT-like zinc ribbon domain zf-C2H2_9 PF16293.5 KFP09831.1 - 0.00085 19.1 9.7 0.8 9.6 0.1 4.0 1 1 3 4 4 4 1 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFP09831.1 - 0.0012 19.2 15.5 0.9 10.0 0.5 3.8 1 1 3 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger Zn_Tnp_IS1595 PF12760.7 KFP09831.1 - 0.0016 18.4 20.7 0.36 10.8 8.7 3.8 1 1 3 4 4 4 2 Transposase zinc-ribbon domain C1_4 PF07975.12 KFP09831.1 - 0.0023 18.1 11.1 0.13 12.6 3.2 3.0 1 1 2 3 3 3 2 TFIIH C1-like domain Mut7-C PF01927.16 KFP09831.1 - 0.0028 17.8 7.5 0.37 10.9 0.1 3.1 1 1 2 3 3 3 1 Mut7-C RNAse domain PyrI_C PF02748.15 KFP09831.1 - 0.0038 17.1 8.6 3.4 7.6 0.1 3.9 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain YhfH PF14149.6 KFP09831.1 - 0.004 17.1 8.1 1.6 8.8 0.1 3.8 4 0 0 4 4 4 1 YhfH-like protein PHD PF00628.29 KFP09831.1 - 0.005 16.7 11.5 0.28 11.1 2.9 3.1 2 1 1 3 3 3 2 PHD-finger CxC7 PF18866.1 KFP09831.1 - 0.0054 16.9 9.9 5.6 7.2 0.2 4.0 1 1 3 4 4 4 0 CxC7 like cysteine cluster associated with KDZ transposases C1_1 PF00130.22 KFP09831.1 - 0.0069 16.2 16.6 1.6 8.6 1.1 4.0 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) YdjO PF14169.6 KFP09831.1 - 0.0099 15.6 6.2 9.2 6.1 0.1 4.0 4 0 0 4 4 4 0 Cold-inducible protein YdjO zf-MYST PF17772.1 KFP09831.1 - 0.011 15.3 4.8 13 5.5 0.1 3.6 1 1 3 4 4 4 0 MYST family zinc finger domain DUF2757 PF10955.8 KFP09831.1 - 0.013 15.8 10.2 6.5 7.1 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2757) DUF4796 PF16044.5 KFP09831.1 - 0.014 15.0 8.3 4.8 6.7 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4796) zf-C2H2_2 PF12756.7 KFP09831.1 - 0.015 15.6 13.1 17 5.8 1.1 3.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ogr_Delta PF04606.12 KFP09831.1 - 0.021 14.8 19.0 1 9.4 0.3 4.1 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.6 KFP09831.1 - 0.024 14.4 40.1 0.12 12.2 3.4 5.2 4 2 0 4 4 4 0 C2H2-type zinc-finger domain TF_Zn_Ribbon PF08271.12 KFP09831.1 - 0.026 14.0 7.7 4.4 6.9 0.2 3.9 4 0 0 4 4 4 0 TFIIB zinc-binding zf-DNA_Pol PF08996.10 KFP09831.1 - 0.026 14.2 6.4 0.67 9.7 0.5 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DUF2256 PF10013.9 KFP09831.1 - 0.029 14.5 8.6 15 5.8 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Thioredoxin_4 PF13462.6 KFP09831.1 - 0.037 14.2 11.2 6.4 6.9 0.1 3.9 3 1 1 4 4 4 0 Thioredoxin Lar_restr_allev PF14354.6 KFP09831.1 - 0.052 13.9 11.5 7.2 7.1 0.1 4.0 4 0 0 4 4 4 0 Restriction alleviation protein Lar PHD_Oberon PF07227.11 KFP09831.1 - 0.063 13.2 4.6 1.3 9.0 1.8 2.8 1 1 1 2 2 2 0 PHD - plant homeodomain finger protein TerY_C PF15616.6 KFP09831.1 - 0.075 13.2 5.2 0.39 10.8 0.7 2.4 1 1 1 2 2 2 0 TerY-C metal binding domain ADK_lid PF05191.14 KFP09831.1 - 0.082 12.9 9.2 9.9 6.2 2.4 3.8 2 1 2 4 4 4 0 Adenylate kinase, active site lid HNH_5 PF14279.6 KFP09831.1 - 0.087 12.7 9.2 39 4.2 0.2 4.1 4 0 0 4 4 4 0 HNH endonuclease DUF2688 PF10892.8 KFP09831.1 - 0.1 12.1 4.6 4.7 6.7 0.1 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF2688) Rad50_zn_hook PF04423.14 KFP09831.1 - 0.1 12.4 10.8 14 5.6 0.1 4.2 2 1 2 4 4 4 0 Rad50 zinc hook motif zf-TFIIB PF13453.6 KFP09831.1 - 0.13 11.6 14.3 4.8 6.6 4.5 3.8 1 1 3 4 4 4 0 Transcription factor zinc-finger zf-C2H2_11 PF16622.5 KFP09831.1 - 0.13 12.0 18.2 0.14 11.9 1.3 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type Desulfoferrod_N PF06397.12 KFP09831.1 - 0.17 11.5 5.1 12 5.7 0.2 3.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Zn_ribbon_recom PF13408.6 KFP09831.1 - 0.17 12.4 9.4 9.2 6.9 0.3 3.2 1 1 3 4 4 4 0 Recombinase zinc beta ribbon domain XPA_N PF01286.18 KFP09831.1 - 0.3 11.2 15.5 13 5.9 0.5 4.1 4 0 0 4 4 4 0 XPA protein N-terminal DUF2225 PF09986.9 KFP09831.1 - 0.31 10.7 12.0 6.7 6.4 0.2 3.9 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) ATPase-cat_bd PF12156.8 KFP09831.1 - 0.32 11.7 15.7 15 6.4 3.3 3.9 3 1 1 4 4 4 0 Putative metal-binding domain of cation transport ATPase Elf1 PF05129.13 KFP09831.1 - 0.33 11.0 12.5 9.2 6.4 0.6 3.5 1 1 3 4 4 3 0 Transcription elongation factor Elf1 like zf-IS66 PF13005.7 KFP09831.1 - 0.36 11.3 17.8 2.2 8.8 0.3 4.1 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DUF983 PF06170.12 KFP09831.1 - 0.39 11.2 10.7 16 5.9 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF983) HscB_4_cys PF18256.1 KFP09831.1 - 0.39 10.6 17.7 1.5 8.7 0.3 4.0 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif zf-RING_7 PF02591.15 KFP09831.1 - 0.42 10.8 0.2 0.42 10.8 0.2 4.1 4 0 0 4 4 3 0 C4-type zinc ribbon domain zf-LITAF-like PF10601.9 KFP09831.1 - 0.46 10.8 15.7 10 6.5 0.9 4.0 2 1 3 5 5 5 0 LITAF-like zinc ribbon domain DUF4379 PF14311.6 KFP09831.1 - 0.55 10.6 11.9 9.1 6.7 1.4 3.2 1 1 3 4 4 4 0 Probable Zinc-ribbon domain FOXP-CC PF16159.5 KFP09831.1 - 0.7 10.6 12.5 22 5.7 0.5 3.9 1 1 3 4 4 4 0 FOXP coiled-coil domain zf-Mss51 PF13824.6 KFP09831.1 - 0.72 10.0 22.1 15 5.8 6.5 3.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_C2H2_ZHX PF18387.1 KFP09831.1 - 1 9.0 13.5 1.6 8.4 0.4 3.8 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain IBR PF01485.21 KFP09831.1 - 1 9.6 14.9 1.2e+03 -0.2 14.8 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Rubredoxin PF00301.20 KFP09831.1 - 1.1 9.4 12.5 16 5.6 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin zf-CCHC_5 PF14787.6 KFP09831.1 - 1.1 9.1 10.7 16 5.3 0.1 4.1 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger zf-RING_5 PF14634.6 KFP09831.1 - 1.2 9.2 15.0 24 5.0 4.0 3.7 2 2 1 3 3 3 0 zinc-RING finger domain DNA_RNApol_7kD PF03604.13 KFP09831.1 - 1.2 8.9 7.4 20 5.0 0.1 3.6 4 0 0 4 4 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-LYAR PF08790.11 KFP09831.1 - 1.2 9.1 13.0 17 5.4 0.4 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-CHCC PF10276.9 KFP09831.1 - 1.3 9.1 14.0 13 6.0 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger domain Cys_rich_CWC PF14375.6 KFP09831.1 - 1.4 9.4 9.9 46 4.5 0.1 4.1 4 0 0 4 4 4 0 Cysteine-rich CWC DUF35_N PF12172.8 KFP09831.1 - 1.6 8.7 16.4 6 6.9 0.5 4.1 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Baculo_IE-1 PF05290.11 KFP09831.1 - 1.8 8.5 12.0 11 6.0 0.2 3.9 3 1 0 4 4 4 0 Baculovirus immediate-early protein (IE-0) HNH PF01844.23 KFP09831.1 - 2.1 8.6 12.6 9 6.6 0.1 4.1 4 0 0 4 4 4 0 HNH endonuclease zf-HIT PF04438.16 KFP09831.1 - 2.5 8.0 15.1 4.8 7.2 0.3 3.7 4 0 0 4 4 3 0 HIT zinc finger DUF3797 PF12677.7 KFP09831.1 - 2.8 7.9 9.3 4.9 7.1 0.0 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF3797) zinc_ribbon_2 PF13240.6 KFP09831.1 - 3.6 7.4 23.1 1.8 8.4 0.8 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-ISL3 PF14690.6 KFP09831.1 - 3.8 8.3 21.5 3.9 8.2 1.5 4.4 2 1 2 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UBZ_FAAP20 PF15750.5 KFP09831.1 - 5.1 7.1 13.9 47 4.0 0.2 4.0 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger DUF2614 PF11023.8 KFP09831.1 - 6.8 6.8 5.8 82 3.3 0.1 3.4 2 2 0 4 4 4 0 Zinc-ribbon containing domain UPF0547 PF10571.9 KFP09831.1 - 7.8 6.7 22.4 5.9 7.1 1.4 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF2072 PF09845.9 KFP09831.1 - 9.1 6.5 13.7 41 4.4 0.3 3.6 3 1 1 4 4 4 0 Zn-ribbon containing protein zf-C2H2 PF00096.26 KFP09832.1 - 8e-11 41.8 10.7 4.1e-05 23.8 0.7 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP09832.1 - 9e-10 38.5 0.6 9e-10 38.5 0.6 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP09832.1 - 6.5e-07 29.7 8.7 0.0049 17.6 3.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP09832.1 - 6.2e-05 23.2 2.0 0.034 14.4 0.5 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KFP09832.1 - 0.0081 16.0 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 KFP09832.1 - 0.015 15.4 4.4 0.093 12.8 3.1 2.1 1 1 1 2 2 2 0 BED zinc finger Arc_trans_TRASH PF08394.10 KFP09832.1 - 0.02 15.2 0.0 3.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal TRASH domain zf-met PF12874.7 KFP09832.1 - 0.025 15.0 5.9 0.85 10.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KFP09832.1 - 0.036 14.0 4.4 0.75 9.7 0.7 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KFP09832.1 - 0.097 12.7 0.5 0.097 12.7 0.5 3.4 2 2 1 3 3 3 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 KFP09832.1 - 0.14 12.7 3.3 0.4 11.2 1.5 2.0 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 KFP09832.1 - 0.54 10.1 7.5 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type V-set PF07686.17 KFP09833.1 - 2.9e-08 33.8 0.2 4.9e-07 29.9 0.2 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Phage_T4_Ndd PF06591.11 KFP09833.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Ig_3 PF13927.6 KFP09833.1 - 0.17 12.5 0.0 0.19 12.4 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain NDK PF00334.19 KFP09834.1 - 1.1e-17 64.3 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase 7tm_4 PF13853.6 KFP09835.1 - 5.7e-51 173.9 10.9 6.7e-51 173.7 10.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP09835.1 - 3.8e-26 92.0 14.2 5.3e-26 91.5 14.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP09835.1 - 0.0084 15.5 3.5 0.0084 15.5 3.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP09835.1 - 0.069 12.5 9.3 0.23 10.8 9.3 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP09835.1 - 1.4 8.4 10.6 0.081 12.5 3.9 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx HS1_rep PF02218.15 KFP09836.1 - 6.3e-62 205.6 44.3 2.1e-17 63.1 2.0 5.5 6 0 0 6 6 6 4 Repeat in HS1/Cortactin SH3_9 PF14604.6 KFP09836.1 - 3.4e-17 62.0 0.2 6.9e-17 61.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09836.1 - 7.4e-16 57.5 0.2 1.6e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP09836.1 - 4e-08 32.8 0.0 9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 KFP09836.1 - 0.02 15.3 0.3 79 3.7 0.0 4.0 2 2 2 4 4 4 0 TMEM210 family S-AdoMet_synt_N PF00438.20 KFP09837.1 - 2.6e-26 92.2 0.5 5.3e-26 91.2 0.5 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 KFP09837.1 - 3.9e-16 59.4 0.0 8.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain EF-hand_3 PF09069.11 KFP09838.1 - 7.3e-31 106.4 0.1 1.8e-30 105.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.11 KFP09838.1 - 5.1e-30 104.2 2.1 9.1e-30 103.3 2.1 1.4 1 0 0 1 1 1 1 EF hand ZZ PF00569.17 KFP09838.1 - 2.1e-08 33.8 12.9 5e-08 32.6 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KFP09838.1 - 0.0029 17.9 10.7 0.006 16.9 10.7 1.5 1 0 0 1 1 1 1 C1 domain MerR-DNA-bind PF09278.11 KFP09838.1 - 0.051 14.1 5.2 0.15 12.6 5.2 1.9 1 0 0 1 1 1 0 MerR, DNA binding CRISPR_Cse2 PF09485.10 KFP09838.1 - 1.8 9.1 10.4 4.5 7.8 10.4 1.7 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) IMD PF08397.11 KFP09839.1 - 4.6e-67 225.6 0.4 1.4e-66 224.0 0.5 1.7 1 1 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFP09839.1 - 2.4e-10 40.1 0.0 5.6e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP09839.1 - 9.9e-08 31.6 0.0 2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP09839.1 - 3.4e-05 23.4 0.0 6.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Snf7 PF03357.21 KFP09840.1 - 5.2e-32 110.8 11.9 6.1e-32 110.6 11.9 1.0 1 0 0 1 1 1 1 Snf7 DYW_deaminase PF14432.6 KFP09840.1 - 0.034 14.0 0.3 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases Raptor_N PF14538.6 KFP09841.1 - 5.2e-64 214.6 0.0 1e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KFP09841.1 - 5.3e-14 51.1 2.7 0.00053 20.0 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KFP09841.1 - 4e-10 39.9 0.0 4.7e-06 26.9 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats WD40 PF00400.32 KFP09841.1 - 4.1e-09 36.9 4.6 0.16 12.9 0.3 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Cnd1 PF12717.7 KFP09841.1 - 3.6e-07 30.4 0.0 0.0003 20.8 0.0 3.5 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP09841.1 - 3.4e-05 24.2 0.2 1.3 9.6 0.0 3.9 3 0 0 3 3 3 2 HEAT-like repeat Hyccin PF09790.9 KFP09841.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Hyccin Endonuclease_5 PF04493.14 KFP09842.1 - 2.8e-65 219.7 0.0 3.2e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF5064 PF16703.5 KFP09843.1 - 0.088 13.3 0.1 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5064) DUF1400 PF07176.11 KFP09843.1 - 5.7 7.2 7.1 3.3 8.0 0.1 3.9 4 2 1 5 5 5 0 Alpha/beta hydrolase of unknown function (DUF1400) Sulfate_transp PF00916.20 KFP09846.1 - 2.9e-68 230.4 4.4 4e-68 229.9 4.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP09846.1 - 3.4e-13 49.2 0.0 5.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFP09846.1 - 1.6e-05 25.2 0.2 3.3e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 STAS domain Sulfatase PF00884.23 KFP09847.1 - 4.3e-12 46.1 0.6 2.2e-09 37.2 0.1 2.8 1 1 0 2 2 2 2 Sulfatase DUF4976 PF16347.5 KFP09847.1 - 1.9e-06 28.0 0.4 0.00016 21.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) BRE1 PF08647.11 KFP09848.1 - 1.4e-17 63.5 14.2 1.4e-17 63.5 14.2 11.3 4 3 8 12 12 12 1 BRE1 E3 ubiquitin ligase NADH_u_ox_C PF12853.7 KFP09848.1 - 0.024 14.6 0.7 0.16 11.9 0.7 2.6 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit RabGAP-TBC PF00566.18 KFP09849.1 - 2.1e-47 161.5 1.8 3.5e-47 160.8 1.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFP09849.1 - 4.7e-07 29.4 0.1 0.028 13.9 0.1 2.3 2 0 0 2 2 2 2 Rab-binding domain (RBD) IF4E PF01652.18 KFP09851.1 - 9.2e-56 188.0 1.2 1.1e-55 187.8 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Synuclein PF01387.17 KFP09852.1 - 5.7e-13 49.2 3.1 3.3e-12 46.8 3.1 1.8 1 1 0 1 1 1 1 Synuclein Cadherin PF00028.17 KFP09853.1 - 8.5e-95 311.4 11.9 2.4e-16 60.0 0.2 9.7 9 1 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.12 KFP09853.1 - 3.2e-12 46.1 0.0 0.033 14.0 0.0 5.2 4 0 0 4 4 4 4 Cadherin-like Cadherin_3 PF16184.5 KFP09853.1 - 1.2e-07 31.7 13.4 0.43 10.6 0.0 8.4 7 2 2 9 9 9 3 Cadherin-like PepSY PF03413.19 KFP09853.1 - 0.055 14.0 0.0 51 4.5 0.0 3.9 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain DUF5065 PF16723.5 KFP09853.1 - 0.059 13.4 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) UBA_4 PF14555.6 KFP09854.1 - 1.3e-07 31.3 0.2 7.1e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain DUF1682 PF07946.14 KFP09854.1 - 8.4e-06 25.2 7.9 1.2e-05 24.7 7.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) UBX PF00789.20 KFP09854.1 - 1.8e-05 24.9 0.2 8.1e-05 22.7 0.2 2.2 1 1 0 1 1 1 1 UBX domain LIM_bind PF01803.16 KFP09854.1 - 0.036 13.6 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 LIM-domain binding protein AAA_23 PF13476.6 KFP09854.1 - 0.055 14.0 10.4 0.12 12.9 10.4 1.6 1 0 0 1 1 1 0 AAA domain NARP1 PF12569.8 KFP09854.1 - 0.12 11.3 11.0 0.18 10.6 11.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Serinc PF03348.15 KFP09854.1 - 0.24 10.3 0.4 0.33 9.8 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4366 PF14283.6 KFP09854.1 - 0.45 10.5 3.9 0.76 9.8 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 KFP09854.1 - 0.88 8.3 6.7 1.3 7.7 6.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFP09854.1 - 2.6 6.2 9.6 3.4 5.8 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 KFP09854.1 - 3.1 5.8 21.3 4.4 5.3 21.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MRP-S26 PF14943.6 KFP09854.1 - 6.3 6.7 20.3 11 5.8 20.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Connexin PF00029.19 KFP09854.1 - 6.4 6.5 5.3 10 5.8 5.3 1.3 1 0 0 1 1 1 0 Connexin Clathrin_lg_ch PF01086.17 KFP09855.1 - 1.4e-37 130.0 8.8 3.6e-37 128.6 8.8 1.6 1 1 0 1 1 1 1 Clathrin light chain Nop16 PF09420.10 KFP09856.1 - 2.9e-15 56.9 1.6 3.4e-15 56.7 1.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Baculo_p33 PF05214.12 KFP09856.1 - 0.0016 18.2 1.5 0.0018 18.1 1.5 1.2 1 0 0 1 1 1 1 Baculovirus P33 DUF3781 PF12636.7 KFP09856.1 - 0.098 12.6 4.1 0.15 11.9 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3781) Arf PF00025.21 KFP09857.1 - 2.4e-39 134.6 0.0 3e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP09857.1 - 1e-09 38.7 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP09857.1 - 4.6e-08 32.7 0.0 5.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP09857.1 - 8.6e-08 31.8 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFP09857.1 - 1.5e-06 27.9 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFP09857.1 - 3e-05 23.3 0.0 0.00023 20.4 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP09857.1 - 0.00021 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KFP09857.1 - 0.00048 20.1 0.3 0.032 14.1 0.2 2.3 1 1 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.27 KFP09857.1 - 0.0031 17.1 0.0 0.0074 15.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP09857.1 - 0.0036 17.7 2.3 0.16 12.3 1.7 2.2 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KFP09857.1 - 0.016 14.8 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFP09857.1 - 0.14 12.7 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DnaGprimase_HBD PF16730.5 KFP09857.1 - 0.17 12.0 0.1 0.26 11.4 0.1 1.2 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain P33MONOX PF15302.6 KFP09858.1 - 4.3e-110 368.0 9.6 4.7e-110 367.9 9.6 1.0 1 0 0 1 1 1 1 P33 mono-oxygenase Kazal_1 PF00050.21 KFP09859.1 - 1.1e-115 377.5 61.7 4.4e-20 71.4 4.6 6.1 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP09859.1 - 1.5e-59 197.9 48.5 6.8e-11 42.1 2.4 6.3 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain FmdE PF02663.14 KFP09859.1 - 0.91 9.6 5.7 0.92 9.6 0.1 3.2 3 0 0 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Kazal_1 PF00050.21 KFP09860.1 - 4.7e-53 177.0 30.9 3e-20 72.0 4.9 3.2 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP09860.1 - 2.1e-26 91.8 28.0 2.7e-10 40.2 2.8 3.6 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain Bunya_nucleocap PF00952.17 KFP09860.1 - 0.059 13.4 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Bunyavirus nucleocapsid (N) protein zf-BED PF02892.15 KFP09860.1 - 0.95 9.5 7.3 2.8 8.1 1.0 3.5 3 0 0 3 3 3 0 BED zinc finger Kazal_1 PF00050.21 KFP09861.1 - 2.5e-17 62.6 4.2 2.9e-17 62.4 4.2 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP09861.1 - 6e-09 35.9 2.7 7.5e-09 35.6 2.7 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain CUB PF00431.20 KFP09862.1 - 8.4e-289 937.0 0.0 3.3e-25 88.6 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.20 KFP09862.1 - 4.3e-236 763.8 162.0 7.7e-11 42.4 0.3 27.5 27 0 0 27 27 27 27 Sushi repeat (SCR repeat) CUB_2 PF02408.20 KFP09862.1 - 5.8e-23 80.9 13.1 0.025 14.3 0.3 11.3 11 0 0 11 11 11 8 CUB-like domain HRM PF02793.22 KFP09862.1 - 0.00034 20.8 73.7 0.36 11.1 0.8 15.4 15 1 1 16 16 16 6 Hormone receptor domain R3H-assoc PF13902.6 KFP09863.1 - 9.2e-32 110.2 0.8 1.3e-31 109.7 0.8 1.2 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KFP09863.1 - 0.0023 17.9 0.2 0.0067 16.4 0.2 1.8 1 0 0 1 1 1 1 R3H domain Med16 PF11635.8 KFP09864.1 - 1e-135 453.5 0.2 1.3e-135 453.2 0.2 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 WD40 PF00400.32 KFP09864.1 - 0.00013 22.7 5.1 0.00028 21.6 1.6 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP09864.1 - 0.00031 21.0 0.3 0.083 13.2 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_5 PF13893.6 KFP09865.1 - 2.3e-61 204.9 1.0 1.7e-43 147.2 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFP09865.1 - 9.3e-38 127.9 1.7 9.1e-11 41.4 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFP09865.1 - 4.1e-15 55.8 0.0 5.2e-14 52.2 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFP09865.1 - 1e-10 41.3 3.5 0.072 12.9 0.0 4.6 5 0 0 5 5 5 4 Occluded RNA-recognition motif AKAP2_C PF15304.6 KFP09866.1 - 1.2e-26 93.9 47.9 2.5e-21 76.4 19.3 6.4 3 2 0 4 4 4 3 A-kinase anchor protein 2 C-terminus Ferlin_C PF16165.5 KFP09868.1 - 2.6e-14 53.4 2.6 1.6e-06 28.1 0.4 2.1 1 1 1 2 2 2 2 Ferlin C-terminus CDP-OH_P_transf PF01066.21 KFP09869.1 - 2.8e-17 63.3 0.2 2.8e-17 63.3 0.2 3.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thiolase_N PF00108.23 KFP09872.1 - 8.1e-83 277.7 0.3 1.2e-82 277.2 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP09872.1 - 2.5e-46 156.3 0.0 5.1e-46 155.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP09872.1 - 7.9e-09 35.5 1.4 3.6e-08 33.3 0.3 2.6 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFP09872.1 - 0.48 10.3 2.8 2.8 7.9 0.2 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3HCDH_N PF02737.18 KFP09873.1 - 5.7e-57 192.5 1.6 1.3e-56 191.3 1.6 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KFP09873.1 - 1.5e-39 135.9 0.1 2.5e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KFP09873.1 - 3.7e-26 91.6 1.4 5.8e-26 90.9 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KFP09873.1 - 6.4e-25 88.3 0.0 1.7e-24 87.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Ras PF00071.22 KFP09874.1 - 9.4e-51 171.6 0.2 1.1e-50 171.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09874.1 - 5.4e-22 78.3 0.1 8e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09874.1 - 1.8e-10 40.6 0.4 2.5e-10 40.1 0.3 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP09874.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP09874.1 - 0.067 12.5 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3963 PF13124.6 KFP09874.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Kinesin PF00225.23 KFP09875.1 - 5.5e-115 383.8 0.0 5.5e-115 383.8 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP09875.1 - 2.7e-25 89.0 0.0 6.4e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 KFP09875.1 - 0.0029 17.8 7.9 0.0029 17.8 7.9 1.7 2 0 0 2 2 2 1 Kinesin-associated SpoIIIAH PF12685.7 KFP09875.1 - 1.2 9.0 10.5 2.7 7.8 10.5 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein TK PF00265.18 KFP09876.1 - 4.8e-47 160.1 0.2 6.3e-47 159.7 0.2 1.2 1 0 0 1 1 1 1 Thymidine kinase Ank_5 PF13857.6 KFP09877.1 - 1.4e-13 50.8 0.7 6.5e-10 39.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP09877.1 - 1.7e-12 47.6 0.1 2.3e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP09877.1 - 3.4e-12 46.8 0.0 5.9e-07 30.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP09877.1 - 1.5e-10 41.0 0.3 3.5e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP09877.1 - 6.3e-10 38.4 0.1 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Thioredoxin PF00085.20 KFP09878.1 - 1.7e-54 182.1 2.5 5.1e-26 90.7 0.0 4.0 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 KFP09878.1 - 1.7e-50 171.5 5.8 2.8e-44 151.2 3.9 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFP09878.1 - 5e-12 45.8 0.1 1.8e-06 27.5 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP09878.1 - 7.9e-10 39.2 0.3 0.0029 18.0 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP09878.1 - 2.3e-07 30.9 0.0 0.023 14.8 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.13 KFP09878.1 - 2.6e-07 30.8 1.4 0.38 10.9 0.1 3.6 4 0 0 4 4 3 3 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 KFP09878.1 - 4.4e-07 30.1 0.1 0.014 15.7 0.0 4.3 3 2 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KFP09878.1 - 6.8e-05 22.8 0.8 0.83 9.6 0.0 3.6 3 1 1 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 KFP09878.1 - 0.0082 15.9 0.5 0.54 10.0 0.0 2.8 2 1 0 2 2 2 1 Redoxin Glutaredoxin PF00462.24 KFP09878.1 - 0.0084 16.3 0.6 3.7 7.8 0.0 3.3 2 1 0 2 2 2 1 Glutaredoxin HyaE PF07449.11 KFP09878.1 - 0.063 13.3 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFP09878.1 - 0.065 13.0 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin Rho_GDI PF02115.17 KFP09879.1 - 2.2e-82 275.5 0.4 2.6e-82 275.3 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4249 PF14054.6 KFP09879.1 - 0.013 15.2 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) FoP_duplication PF13865.6 KFP09880.1 - 5.8e-11 42.8 15.1 1.3e-10 41.7 15.2 1.7 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KFP09880.1 - 3.2e-09 36.5 0.0 4.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTP_transf_like PF01467.26 KFP09881.1 - 1.2e-37 129.3 0.0 1e-22 80.9 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KFP09881.1 - 0.0027 17.6 0.1 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 FAD synthetase CHAP PF05257.16 KFP09881.1 - 0.02 15.4 0.0 0.064 13.8 0.0 1.7 1 1 0 1 1 1 0 CHAP domain SIR2 PF02146.17 KFP09882.1 - 7.6e-24 84.6 3.7 1.7e-21 76.9 0.7 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFP09882.1 - 0.0033 17.1 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_Maf PF03131.17 KFP09883.1 - 1.3e-33 115.4 11.7 1.6e-33 115.1 11.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP09883.1 - 3.5e-05 23.8 15.7 0.00035 20.6 15.7 2.3 1 1 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 KFP09883.1 - 9.9e-05 22.0 5.8 9.9e-05 22.0 5.8 2.2 1 1 1 2 2 2 1 Septum formation initiator Prominin PF05478.11 KFP09883.1 - 0.00039 18.6 1.4 0.00047 18.3 1.4 1.0 1 0 0 1 1 1 1 Prominin DUF1192 PF06698.11 KFP09883.1 - 0.00056 19.9 5.7 0.024 14.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF4164 PF13747.6 KFP09883.1 - 0.0021 18.3 2.9 0.0021 18.3 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) DUF2353 PF09789.9 KFP09883.1 - 0.003 17.0 5.9 0.0036 16.7 5.9 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Cnn_1N PF07989.11 KFP09883.1 - 0.0061 16.7 8.7 0.014 15.6 8.7 1.7 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 KFP09883.1 - 0.0071 16.5 2.6 0.0071 16.5 2.6 2.2 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II HAUS-augmin3 PF14932.6 KFP09883.1 - 0.014 15.0 6.2 0.017 14.7 6.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ThrE_2 PF12821.7 KFP09883.1 - 0.015 15.4 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE FapA PF03961.13 KFP09883.1 - 0.017 13.8 4.9 0.022 13.4 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tox-ODYAM1 PF15642.6 KFP09883.1 - 0.069 12.1 3.3 0.087 11.8 3.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus bZIP_2 PF07716.15 KFP09883.1 - 0.074 13.1 16.8 0.11 12.5 13.4 2.7 1 1 1 2 2 2 0 Basic region leucine zipper Mod_r PF07200.13 KFP09883.1 - 0.083 13.0 7.6 0.11 12.6 7.2 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KFP09883.1 - 0.11 13.2 8.4 0.055 14.1 3.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF3584 PF12128.8 KFP09883.1 - 0.22 9.0 8.4 0.25 8.8 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GIT_CC PF16559.5 KFP09883.1 - 0.28 11.1 6.0 0.24 11.3 4.1 1.9 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 KFP09883.1 - 0.42 9.9 5.0 0.3 10.4 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 KFP09883.1 - 0.43 10.4 10.9 0.64 9.9 10.9 1.3 1 0 0 1 1 1 0 Spc19 Spc7 PF08317.11 KFP09883.1 - 0.84 8.5 11.5 2.2 7.1 11.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein BST2 PF16716.5 KFP09883.1 - 0.86 10.2 9.6 1.7 9.3 9.2 1.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mst1_SARAH PF11629.8 KFP09883.1 - 1 9.5 9.6 4.9 7.3 2.9 2.8 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Nup54 PF13874.6 KFP09883.1 - 1.1 9.4 8.9 1.5 8.9 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ZapB PF06005.12 KFP09883.1 - 1.3 9.5 16.4 1.3 9.5 8.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 KFP09883.1 - 1.9 8.7 9.1 0.63 10.3 5.4 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2205 PF10224.9 KFP09883.1 - 2.1 8.4 9.8 0.73 9.9 4.9 2.1 1 1 1 2 2 2 0 Short coiled-coil protein APG6_N PF17675.1 KFP09883.1 - 2.3 8.8 15.2 8.6 6.9 15.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 KFP09883.1 - 7.9 7.0 8.1 48 4.5 8.1 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.18 KFP09883.1 - 8.8 6.6 13.4 11 6.3 4.2 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper P5CR_dimer PF14748.6 KFP09884.1 - 1.5e-37 128.0 0.0 2.2e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation MARVEL PF01284.23 KFP09885.1 - 1.9e-24 86.3 44.9 3.6e-14 53.0 13.8 2.0 2 0 0 2 2 2 2 Membrane-associating domain HR_lesion PF05514.11 KFP09885.1 - 0.65 10.2 7.8 0.24 11.6 2.9 2.3 2 0 0 2 2 2 0 HR-like lesion-inducing PAE PF03283.13 KFP09886.1 - 1.4e-64 218.5 0.0 1.8e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase UBX PF00789.20 KFP09887.1 - 2.1e-12 47.0 0.0 1.8e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.8 KFP09887.1 - 5.5e-07 29.7 0.1 1.1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain LRR_6 PF13516.6 KFP09888.1 - 5e-15 54.2 12.1 0.0015 18.4 0.2 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 KFP09888.1 - 0.0043 17.4 13.3 2.5 9.0 1.2 6.0 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KFP09888.1 - 0.0074 16.0 15.0 0.4 10.5 2.3 3.9 2 1 0 2 2 2 2 Leucine rich repeat Baculo_PEP_C PF04513.12 KFP09888.1 - 0.02 14.9 1.8 0.02 14.9 1.8 3.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCR_D PF02505.14 KFP09888.1 - 0.025 14.4 0.5 5 7.0 0.0 2.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D LRR_4 PF12799.7 KFP09888.1 - 0.33 11.4 14.3 1.3 9.5 2.9 3.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Ras PF00071.22 KFP09889.1 - 3.1e-50 169.9 0.0 3.6e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP09889.1 - 6.5e-19 68.3 0.0 8.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP09889.1 - 4e-05 23.1 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CagD PF16567.5 KFP09889.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD adh_short_C2 PF13561.6 KFP09890.1 - 3.8e-33 115.0 0.4 4.2e-33 114.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP09890.1 - 1.7e-23 83.1 0.3 2e-23 82.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RPN7 PF10602.9 KFP09891.1 - 2.3e-61 206.5 0.3 4.8e-61 205.5 0.3 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFP09891.1 - 2e-17 63.6 1.1 6.9e-17 61.9 0.2 2.2 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFP09891.1 - 0.0048 16.9 4.5 0.16 12.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP09891.1 - 0.034 13.8 1.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KFP09891.1 - 0.092 12.6 5.2 0.19 11.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Dus PF01207.17 KFP09892.1 - 2.9e-56 190.8 0.0 4.2e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF702 PF05142.12 KFP09892.1 - 0.00012 22.5 5.7 0.00027 21.5 5.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF702) Ribosomal_S14 PF00253.21 KFP09892.1 - 0.0038 17.0 1.0 0.0093 15.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e His_biosynth PF00977.21 KFP09892.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.17 KFP09892.1 - 0.058 12.7 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase DHO_dh PF01180.21 KFP09892.1 - 0.11 11.7 0.0 0.38 9.9 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 KFP09892.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase SOR_SNZ PF01680.17 KFP09892.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.5 1 1 0 1 1 1 0 SOR/SNZ family Acyl_transf_1 PF00698.21 KFP09893.1 - 3.2e-115 385.0 0.0 5.9e-115 384.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KFP09893.1 - 1.2e-72 244.6 0.0 2.2e-72 243.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.20 KFP09893.1 - 5.7e-64 216.4 0.1 2.3e-62 211.1 0.2 2.6 2 0 0 2 2 2 1 Thioesterase domain KR PF08659.10 KFP09893.1 - 1.8e-46 158.3 0.0 5.6e-46 156.7 0.0 1.9 2 0 0 2 2 2 1 KR domain KAsynt_C_assoc PF16197.5 KFP09893.1 - 7.4e-33 113.3 0.0 2.1e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 KFP09893.1 - 2.7e-31 108.0 0.0 6.1e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFP09893.1 - 1.4e-18 67.2 0.0 2.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 KFP09893.1 - 1.2e-15 57.7 0.0 4.4e-15 55.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP09893.1 - 4.6e-15 56.9 0.1 1.1e-13 52.4 0.1 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KFP09893.1 - 7.2e-09 35.9 1.9 9.9e-09 35.4 0.7 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KFP09893.1 - 1.5e-06 27.7 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 KFP09893.1 - 8e-06 25.4 0.0 0.00011 21.7 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase ACP_syn_III PF08545.10 KFP09893.1 - 0.0069 16.2 0.2 0.029 14.2 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YjeF_N PF03853.15 KFP09893.1 - 0.012 15.5 0.0 1.4 8.8 0.0 3.6 4 0 0 4 4 4 0 YjeF-related protein N-terminus Methyltransf_12 PF08242.12 KFP09893.1 - 0.02 15.6 0.0 0.073 13.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain ICAT PF06384.11 KFP09894.1 - 0.02 15.1 0.1 0.027 14.7 0.1 1.3 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT DivIC PF04977.15 KFP09895.1 - 0.015 15.0 0.9 0.016 15.0 0.9 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF4763 PF15960.5 KFP09895.1 - 0.016 14.6 0.2 0.016 14.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) BLOC1S3 PF15753.5 KFP09895.1 - 0.025 14.7 0.1 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 NYD-SP28_assoc PF14775.6 KFP09895.1 - 0.065 13.4 0.2 0.074 13.2 0.2 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain MFS_1 PF07690.16 KFP09896.1 - 7.6e-39 133.6 42.6 8.2e-35 120.4 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KFP09897.1 - 2.3e-20 73.0 0.0 2.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09897.1 - 7.4e-13 48.4 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP09897.1 - 5.4e-10 38.6 0.1 9.4e-10 37.8 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP09897.1 - 0.00038 20.5 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFP09897.1 - 0.048 12.6 0.1 0.069 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFP09897.1 - 0.091 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NHL PF01436.21 KFP09898.1 - 5.2e-12 45.2 3.0 1.7e-06 27.8 0.0 4.8 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 KFP09898.1 - 0.00067 19.3 0.4 0.25 10.9 0.1 3.3 3 2 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Tachylectin PF14517.6 KFP09898.1 - 0.0056 16.2 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Tachylectin Proteasome_A_N PF10584.9 KFP09898.1 - 0.1 12.3 0.1 0.53 10.0 0.0 2.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature US22 PF02393.16 KFP09898.1 - 0.16 12.2 0.1 27 5.0 0.0 2.8 2 1 1 3 3 3 0 US22 like DUF4476 PF14771.6 KFP09900.1 - 1.8e-21 76.3 4.5 2.3e-19 69.5 4.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4476) Band_7 PF01145.25 KFP09901.1 - 1.3e-28 100.2 1.0 1.6e-28 99.9 1.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFP09901.1 - 0.0041 16.8 0.1 0.0064 16.2 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFP09901.1 - 0.12 12.8 0.3 0.26 11.7 0.3 1.5 1 0 0 1 1 1 0 Phage protein Gp68 TED_complement PF07678.14 KFP09902.1 - 1.8e-85 286.8 3.9 3.8e-85 285.7 3.9 1.6 1 1 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 KFP09902.1 - 3.8e-30 103.6 0.2 1.9e-29 101.4 0.2 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFP09902.1 - 5.7e-26 91.1 3.6 5.5e-25 87.9 0.0 3.7 3 0 0 3 3 3 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 KFP09902.1 - 5.7e-25 88.3 1.6 1.1e-20 74.4 0.0 4.2 4 0 0 4 4 4 2 Alpha-2-macroglobulin bait region domain NTR PF01759.21 KFP09902.1 - 7.9e-25 86.7 0.5 2.6e-24 85.1 0.5 2.0 1 0 0 1 1 1 1 UNC-6/NTR/C345C module MG1 PF17790.1 KFP09902.1 - 6.3e-21 74.7 1.2 2.4e-20 72.8 1.2 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG1 MG2 PF01835.19 KFP09902.1 - 1.3e-18 67.2 0.9 2e-14 53.8 0.0 4.7 5 0 0 5 5 5 1 MG2 domain MG3 PF17791.1 KFP09902.1 - 2.2e-14 53.5 0.1 1e-13 51.3 0.1 2.3 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG4 PF17789.1 KFP09902.1 - 2.7e-10 40.2 0.2 1.5e-09 37.9 0.0 2.5 2 0 0 2 2 2 1 Macroglobulin domain MG4 ANATO PF01821.18 KFP09902.1 - 2.9e-10 40.8 6.4 9.8e-10 39.1 6.4 2.0 1 0 0 1 1 1 1 Anaphylotoxin-like domain Ion_trans PF00520.31 KFP09905.1 - 3e-33 115.1 14.1 4.5e-33 114.5 14.1 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFP09905.1 - 1.2e-28 99.0 0.8 2.8e-28 97.9 0.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFP09905.1 - 6.2e-10 39.5 0.4 2.6e-05 24.7 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP09905.1 - 6.3e-09 36.2 0.0 0.00097 19.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP09905.1 - 2e-06 27.7 2.8 0.13 12.9 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat PKD_channel PF08016.12 KFP09905.1 - 3.7e-05 22.6 13.6 0.00034 19.4 13.6 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ank_5 PF13857.6 KFP09905.1 - 6.4e-05 23.2 0.1 1.1 9.6 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP09905.1 - 0.00015 22.0 0.4 1 9.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Gp-FAR-1 PF05823.12 KFP09905.1 - 0.46 10.8 5.0 7.1 7.0 0.1 2.9 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fasciclin PF02469.22 KFP09906.1 - 5e-106 350.1 0.0 8.9e-28 97.1 0.4 4.4 4 0 0 4 4 4 4 Fasciclin domain RNase_PH PF01138.21 KFP09913.1 - 2.4e-24 86.3 0.1 4.7e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP09913.1 - 3.4e-12 46.2 0.0 6.4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycos_transf_2 PF00535.26 KFP09914.1 - 1.2e-23 83.8 0.0 1.5e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFP09914.1 - 3.3e-08 33.7 0.0 5.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFP09914.1 - 0.00065 19.3 0.0 0.00081 18.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pribosyltran PF00156.27 KFP09914.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain MH2 PF03166.14 KFP09915.1 - 1.4e-74 250.3 1.6 1.9e-74 249.9 1.6 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP09915.1 - 1.5e-42 143.9 1.2 3.6e-42 142.8 1.2 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP09915.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFP09915.1 - 0.02 14.8 0.5 0.044 13.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) SRTM1 PF15872.5 KFP09917.1 - 2.1e-52 175.6 9.7 2.3e-52 175.4 9.7 1.0 1 0 0 1 1 1 1 Serine-rich and transmembrane domain-containing protein 1 Cyclin_N PF00134.23 KFP09918.1 - 3e-47 159.5 0.1 4.8e-47 158.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP09918.1 - 5.4e-29 100.7 1.7 8.7e-29 100.0 0.6 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N2 PF16500.5 KFP09918.1 - 0.01 16.6 0.1 0.017 15.9 0.1 1.3 1 0 0 1 1 1 0 N-terminal region of cyclin_N Big_10 PF17964.1 KFP09918.1 - 0.079 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig domain Mltc_N PF11873.8 KFP09918.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain DCX PF03607.17 KFP09920.1 - 5.1e-37 125.8 0.1 5.5e-23 80.8 0.0 2.5 2 0 0 2 2 2 2 Doublecortin Pkinase PF00069.25 KFP09921.1 - 2.1e-75 253.5 0.0 2.6e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09921.1 - 2.9e-34 118.5 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP09921.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP09921.1 - 0.00039 19.8 0.0 0.00087 18.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP09921.1 - 0.0016 17.3 0.4 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFP09921.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFP09921.1 - 0.12 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Beach PF02138.18 KFP09922.1 - 4.2e-124 413.4 0.7 6.4e-124 412.8 0.7 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 KFP09922.1 - 1e-110 369.4 2.5 1e-110 369.4 2.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 KFP09922.1 - 5.2e-88 293.1 9.1 5.2e-88 293.1 9.1 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 KFP09922.1 - 5.7e-30 103.4 0.7 2.7e-29 101.2 0.0 2.5 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KFP09922.1 - 1.4e-11 44.8 0.0 4.3e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KFP09922.1 - 5.2e-06 27.1 11.5 1.1 10.2 0.3 7.1 7 0 0 7 7 7 2 WD domain, G-beta repeat PIGA PF08288.12 KFP09922.1 - 0.045 14.3 0.4 0.16 12.5 0.4 2.0 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) RTP1_C1 PF10363.9 KFP09922.1 - 0.18 12.0 0.7 1.3 9.2 0.3 2.5 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 VHS PF00790.19 KFP09922.1 - 0.19 11.6 0.7 7.2 6.4 0.0 3.4 3 0 0 3 3 3 0 VHS domain Mab-21 PF03281.14 KFP09923.1 - 1.8e-98 329.5 0.0 2.3e-98 329.2 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein RVT_1 PF00078.27 KFP09925.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol3_delta2 PF13177.6 KFP09929.1 - 5.9e-10 39.2 0.7 8.5e-10 38.6 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KFP09929.1 - 4.8e-06 27.0 0.0 9.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KFP09929.1 - 6.6e-06 26.0 0.3 1.2e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KFP09929.1 - 0.002 18.4 0.1 0.012 15.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFP09929.1 - 0.0043 17.0 0.1 0.009 16.0 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 KFP09929.1 - 0.0048 17.4 0.0 0.0084 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KFP09929.1 - 0.008 16.6 0.1 0.032 14.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 KFP09929.1 - 0.014 15.8 0.1 0.053 13.9 0.0 2.0 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF2247 PF10004.9 KFP09929.1 - 0.053 13.3 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ATPgrasp_ST PF14397.6 KFP09929.1 - 0.094 12.0 0.1 0.23 10.7 0.1 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp CHB_HEX PF03173.13 KFP09929.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate binding domain Sigma54_activ_2 PF14532.6 KFP09929.1 - 0.31 11.2 1.6 0.49 10.5 0.4 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain START PF01852.19 KFP09931.1 - 1.1e-41 142.5 0.5 2e-41 141.7 0.5 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFP09931.1 - 9e-36 123.0 0.7 1.8e-35 122.0 0.7 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_1 PF00232.18 KFP09932.1 - 6.9e-124 413.7 17.4 5.2e-75 252.6 7.5 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 1 Hepatitis_core PF00906.20 KFP09933.1 - 0.0054 16.3 0.6 0.059 12.9 0.0 2.6 3 0 0 3 3 3 1 Hepatitis core antigen Cnd1 PF12717.7 KFP09933.1 - 0.0059 16.7 16.6 0.31 11.1 0.5 6.1 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP09933.1 - 0.0061 16.7 4.1 1.7 9.1 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat PI-TkoII_IV PF18714.1 KFP09933.1 - 0.05 13.1 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV FANCI_S2 PF14676.6 KFP09933.1 - 0.17 12.2 2.1 3.6 7.9 0.1 3.5 2 1 1 3 3 3 0 FANCI solenoid 2 HEAT_EZ PF13513.6 KFP09933.1 - 0.31 11.6 2.3 1.5e+02 3.0 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Nipped-B_C PF12830.7 KFP09933.1 - 3.1 7.7 5.6 15 5.5 0.0 4.2 5 1 1 6 6 6 0 Sister chromatid cohesion C-terminus AAA_33 PF13671.6 KFP09934.1 - 1.9e-17 63.8 0.0 4.6e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFP09934.1 - 6.9e-06 25.5 0.0 1.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KFP09934.1 - 0.00011 22.8 0.0 0.00053 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFP09934.1 - 0.0016 18.0 2.0 0.0041 16.6 0.1 2.6 2 1 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 KFP09934.1 - 0.0055 17.2 0.2 0.026 15.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KFP09934.1 - 0.018 15.4 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Tmemb_cc2 PF10267.9 KFP09934.1 - 0.24 10.5 8.2 0.43 9.7 8.2 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3324 PF11797.8 KFP09935.1 - 0.06 13.3 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) AAA_33 PF13671.6 KFP09936.1 - 3e-06 27.5 0.1 5.5e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain BRCA-2_helical PF09169.10 KFP09937.1 - 5e-93 310.0 0.0 1.3e-92 308.6 0.0 1.8 1 0 0 1 1 1 1 BRCA2, helical BRCA-2_OB3 PF09104.10 KFP09937.1 - 3.9e-51 172.4 0.2 1.3e-50 170.7 0.2 2.0 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 PF00634.18 KFP09937.1 - 9.4e-51 169.2 32.6 1.8e-11 43.5 0.2 7.7 7 0 0 7 7 7 6 BRCA2 repeat BRCA-2_OB1 PF09103.10 KFP09937.1 - 2.6e-41 140.4 0.0 8.6e-41 138.7 0.0 2.0 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.10 KFP09937.1 - 1.9e-21 75.9 3.8 5.6e-21 74.5 3.8 1.9 1 0 0 1 1 1 1 Tower DUF5534 PF17686.1 KFP09937.1 - 0.039 14.2 2.3 0.16 12.3 2.3 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5534) NUMOD4 PF07463.11 KFP09937.1 - 0.081 13.1 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 NUMOD4 motif DUF45 PF01863.17 KFP09937.1 - 1.7 8.6 5.6 1.8 8.6 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 zf-3CxxC PF13695.6 KFP09938.1 - 3.9e-09 36.9 17.0 6.7e-09 36.1 17.0 1.4 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 KFP09938.1 - 0.00023 21.8 22.8 0.00023 21.8 22.8 2.4 2 1 0 2 2 2 1 Zinc-binding domain Fringe PF02434.16 KFP09939.1 - 2.6e-65 220.4 0.0 5.8e-57 193.0 0.0 2.6 2 1 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 KFP09939.1 - 8.2e-09 35.5 0.0 0.037 13.8 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase DUF604 PF04646.12 KFP09939.1 - 7.8e-06 25.5 0.2 0.00014 21.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Glycos_transf_2 PF00535.26 KFP09939.1 - 0.012 15.4 0.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.20 KFP09940.1 - 2e-155 518.4 8.3 4.5e-155 517.2 1.7 3.0 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KFP09940.1 - 0.0029 16.5 0.1 0.27 10.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein MAPEG PF01124.18 KFP09941.1 - 1.1e-06 28.5 3.2 1.4e-06 28.2 3.2 1.2 1 0 0 1 1 1 1 MAPEG family DUF4650 PF15509.6 KFP09942.1 - 5.1e-159 530.9 32.6 5.1e-159 530.9 32.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4650) Peptidase_C98 PF15499.6 KFP09942.1 - 7.3e-126 419.2 9.0 7.3e-126 419.2 9.0 1.8 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase GHL5 PF14872.6 KFP09942.1 - 0.0089 14.1 0.0 0.013 13.5 0.0 1.1 1 0 0 1 1 1 1 Hypothetical glycoside hydrolase 5 HMG_box PF00505.19 KFP09943.1 - 3.7e-42 142.6 12.6 2e-27 95.4 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP09943.1 - 8.8e-41 138.4 12.7 9.9e-27 93.4 7.4 2.7 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 KFP09943.1 - 0.034 14.1 15.9 0.48 10.4 3.9 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Astro_capsid_p PF12226.8 KFP09943.1 - 1.8 7.7 17.0 2.4 7.2 17.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-I PF07778.11 KFP09943.1 - 3 6.4 7.6 4.4 5.9 7.6 1.2 1 0 0 1 1 1 0 Mis6 NOA36 PF06524.12 KFP09943.1 - 6 6.1 27.3 0.099 11.9 20.4 1.6 2 0 0 2 2 2 0 NOA36 protein AAA PF00004.29 KFP09944.1 - 6.9e-40 136.5 0.0 1.6e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP09944.1 - 5.9e-14 51.6 2.5 1.5e-13 50.3 0.4 2.8 2 1 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 KFP09944.1 - 1.2e-09 38.0 0.3 1.1e-08 34.9 0.0 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFP09944.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP09944.1 - 2.2e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFP09944.1 - 2.9e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFP09944.1 - 3.7e-05 24.2 0.2 0.028 14.8 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFP09944.1 - 0.00018 21.5 0.3 0.0016 18.4 0.2 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP09944.1 - 0.0003 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KFP09944.1 - 0.00074 19.0 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KFP09944.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFP09944.1 - 0.0025 17.8 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFP09944.1 - 0.0035 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFP09944.1 - 0.005 17.4 0.3 0.023 15.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP09944.1 - 0.005 17.1 0.6 0.076 13.3 0.2 2.7 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 KFP09944.1 - 0.008 15.7 0.3 0.019 14.5 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KFP09944.1 - 0.012 15.3 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFP09944.1 - 0.03 13.7 0.2 2.5 7.4 0.1 2.4 1 1 1 2 2 2 0 KaiC TPR_8 PF13181.6 KFP09944.1 - 0.046 14.0 1.4 3.1 8.2 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat NACHT PF05729.12 KFP09944.1 - 0.046 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KFP09944.1 - 0.054 13.7 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFP09944.1 - 0.055 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KFP09944.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.21 KFP09944.1 - 0.13 11.9 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 KFP09944.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFP09944.1 - 0.16 11.5 0.3 0.61 9.6 0.3 1.9 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 KFP09944.1 - 0.22 12.0 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain TPR_2 PF07719.17 KFP09944.1 - 0.66 10.2 2.0 35 4.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad60-SLD_2 PF13881.6 KFP09946.1 - 3.7e-33 113.9 0.0 4.2e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP09946.1 - 8.9e-05 22.2 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFP09946.1 - 0.045 14.3 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Met_gamma_lyase PF06838.11 KFP09946.1 - 0.077 11.5 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase AA_permease_2 PF13520.6 KFP09947.1 - 4.4e-51 174.1 23.3 4.4e-51 174.1 23.3 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFP09947.1 - 1.6e-39 135.8 22.2 1.6e-39 135.8 22.2 2.5 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP09947.1 - 2.9e-25 88.1 7.5 2.9e-25 88.1 7.5 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease DUF3278 PF11683.8 KFP09947.1 - 0.061 13.4 8.5 0.12 12.4 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) RTBV_P46 PF06216.11 KFP09948.1 - 0.0071 15.3 1.1 0.0077 15.2 1.1 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein Terminase_2 PF03592.16 KFP09948.1 - 0.0099 16.4 1.3 0.011 16.2 1.3 1.1 1 0 0 1 1 1 1 Terminase small subunit NPV_P10 PF05531.12 KFP09948.1 - 0.014 15.9 2.2 0.019 15.4 2.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4686 PF15742.5 KFP09948.1 - 0.053 12.6 10.7 0.061 12.4 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DcrB PF08786.11 KFP09948.1 - 0.067 13.3 0.9 0.1 12.7 0.8 1.3 1 1 0 1 1 1 0 DcrB YabA PF06156.13 KFP09948.1 - 0.073 13.7 7.3 0.093 13.4 7.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 KFP09948.1 - 0.082 11.8 9.2 0.1 11.5 9.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Wtap PF17098.5 KFP09948.1 - 0.099 12.6 9.3 0.15 12.0 9.3 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family DUF4600 PF15372.6 KFP09948.1 - 0.14 12.6 9.4 0.17 12.3 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF3573 PF12097.8 KFP09948.1 - 0.18 10.6 1.7 0.2 10.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ZapB PF06005.12 KFP09948.1 - 0.2 12.1 19.4 0.27 11.7 19.4 1.2 1 0 0 1 1 1 0 Cell division protein ZapB DUF2205 PF10224.9 KFP09948.1 - 0.2 11.7 7.9 0.31 11.1 7.6 1.5 1 1 0 1 1 1 0 Short coiled-coil protein UPF0242 PF06785.11 KFP09948.1 - 0.4 10.7 13.5 0.48 10.5 13.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uso1_p115_C PF04871.13 KFP09948.1 - 0.74 10.2 10.8 0.91 9.9 10.8 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region NYD-SP28_assoc PF14775.6 KFP09948.1 - 0.77 9.9 17.3 0.17 12.0 3.4 3.0 1 1 2 3 3 3 0 Sperm tail C-terminal domain GrpE PF01025.19 KFP09948.1 - 0.95 9.1 10.7 1.1 8.9 10.7 1.1 1 0 0 1 1 1 0 GrpE TSC22 PF01166.18 KFP09948.1 - 1 9.7 8.5 0.6 10.5 1.9 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Fungal_TACC PF12709.7 KFP09948.1 - 1.1 9.7 10.1 1.8 9.0 10.1 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 KFP09948.1 - 2.9 7.1 11.3 3.2 7.0 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 KFP09948.1 - 3.1 7.9 12.8 0.56 10.3 3.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KFP09948.1 - 3.5 7.5 13.1 36 4.2 13.1 2.1 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 KFP09948.1 - 4.7 7.4 18.5 0.47 10.6 5.6 3.0 2 1 1 3 3 3 0 Basic region leucine zipper RVT_1 PF00078.27 KFP09949.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 KFP09952.1 - 9e-62 204.7 39.8 2.3e-16 59.3 2.6 5.5 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP09952.1 - 8.4e-22 76.9 23.4 2.2e-05 24.7 2.0 6.4 2 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP09952.1 - 1.3e-20 73.6 0.0 5.2e-10 39.4 0.0 3.0 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP09952.1 - 4.1e-14 52.5 2.7 2e-06 27.4 0.5 3.2 1 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFP09952.1 - 3.4e-11 42.1 21.3 0.16 12.6 0.6 10.0 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP09952.1 - 5.5e-09 35.4 20.9 2 8.6 0.0 8.7 10 0 0 10 10 9 3 Leucine Rich repeat LRRNT PF01462.18 KFP09952.1 - 0.00084 18.9 1.5 0.00084 18.9 1.5 2.7 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_12 PF18837.1 KFP09952.1 - 0.0021 17.6 0.6 0.23 11.2 0.0 3.6 4 0 0 4 4 4 1 Leucine-rich repeat HemY_N PF07219.13 KFP09952.1 - 0.0093 16.1 0.3 0.016 15.4 0.3 1.4 1 0 0 1 1 1 1 HemY protein N-terminus UL97 PF06734.12 KFP09952.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 UL97 Ni_hydr_CYTB PF01292.20 KFP09952.1 - 0.064 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF5305 PF17231.2 KFP09952.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SARAF PF06682.12 KFP09952.1 - 0.12 12.0 0.2 3.7 7.1 0.1 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Pyrid_oxidase_2 PF13883.6 KFP09952.1 - 0.12 12.3 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF4519 PF15012.6 KFP09952.1 - 4.2 7.6 5.0 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Vinculin PF01044.19 KFP09953.1 - 3.3e-213 710.8 21.4 3.7e-213 710.7 21.4 1.0 1 0 0 1 1 1 1 Vinculin family I_LWEQ PF01608.17 KFP09953.1 - 0.016 15.5 3.9 0.016 15.5 3.9 4.2 3 2 0 3 3 3 0 I/LWEQ domain DUF4872 PF16169.5 KFP09953.1 - 0.14 11.9 0.7 5.2 6.8 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4872) Baculo_gp41 PF04700.12 KFP09953.1 - 0.28 11.0 3.2 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 Structural glycoprotein p40/gp41 conserved region XPC-binding PF09280.11 KFP09954.1 - 4.1e-26 90.5 19.0 7e-26 89.7 19.0 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 KFP09954.1 - 4.3e-26 90.4 2.5 9.8e-14 50.9 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KFP09954.1 - 1.2e-13 50.6 0.3 2.6e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UBA_3 PF09288.10 KFP09954.1 - 0.00043 20.0 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KFP09954.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFP09954.1 - 0.1 13.2 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1421 PF07223.11 KFP09954.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain (DUF1421) UBA_2 PF08587.11 KFP09954.1 - 0.11 12.6 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF1296 PF06972.11 KFP09954.1 - 0.12 12.6 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) STI1 PF17830.1 KFP09954.1 - 1.8 8.6 6.4 11 6.0 6.3 2.3 1 1 0 1 1 1 0 STI1 domain TFIIA PF03153.13 KFP09954.1 - 9.3 6.1 9.9 12 5.7 9.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 KFP09955.1 - 1.6e-17 62.9 21.7 8e-06 26.0 2.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP09955.1 - 3e-11 43.2 11.1 9.2e-07 29.0 2.9 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP09955.1 - 2e-09 37.5 19.8 0.0043 17.8 2.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP09955.1 - 0.018 15.5 4.4 1.4 9.4 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFP09955.1 - 0.023 15.3 6.6 2.2 8.9 1.7 2.7 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP09955.1 - 0.038 14.3 3.4 0.073 13.4 3.4 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 KFP09955.1 - 0.045 14.2 6.0 1.5 9.4 2.0 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3850 PF12961.7 KFP09955.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-C2H2_11 PF16622.5 KFP09955.1 - 0.23 11.3 9.3 8.8 6.2 1.0 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP09955.1 - 0.77 10.1 6.8 4.2 7.8 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KFP09955.1 - 3.7 8.3 8.6 0.79 10.5 2.1 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 KFP09957.1 - 8e-07 29.2 1.5 8e-07 29.2 1.5 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP09957.1 - 1.6e-06 28.3 1.4 2.5e-06 27.7 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KFP09957.1 - 9.7e-05 22.4 0.3 9.7e-05 22.4 0.3 2.5 4 0 0 4 4 4 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 KFP09957.1 - 0.00015 21.4 1.0 0.00026 20.7 1.0 1.4 1 0 0 1 1 1 1 U1 zinc finger Cgr1 PF03879.14 KFP09957.1 - 0.016 15.6 17.5 0.016 15.6 17.5 2.1 2 0 0 2 2 2 0 Cgr1 family DUF4250 PF14056.6 KFP09957.1 - 0.046 13.7 0.4 0.13 12.3 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4250) zf-C2H2 PF00096.26 KFP09957.1 - 0.75 10.4 3.9 0.26 11.8 1.0 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Presenilin PF01080.17 KFP09957.1 - 3.1 6.5 3.8 3 6.5 3.8 1.2 1 0 0 1 1 1 0 Presenilin Vma12 PF11712.8 KFP09957.1 - 3.6 7.7 8.6 26 4.9 5.7 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Vfa1 PF08432.10 KFP09957.1 - 8.4 6.7 24.0 0.13 12.6 14.6 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 tRNA-synt_His PF13393.6 KFP09958.1 - 1.4e-25 90.3 0.0 7.9e-22 77.9 0.0 2.4 2 1 1 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFP09958.1 - 5.9e-17 61.6 1.2 1.3e-16 60.5 1.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KFP09958.1 - 3.6e-09 36.5 0.5 5.1e-09 36.0 0.5 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KFP09958.1 - 0.00049 19.3 0.0 0.0015 17.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Virul_Fac PF10139.9 KFP09958.1 - 0.076 11.2 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor FAM198 PF15051.6 KFP09958.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein Fe-S_biosyn PF01521.20 KFP09958.1 - 0.11 12.7 0.0 0.52 10.5 0.0 2.1 3 0 0 3 3 3 0 Iron-sulphur cluster biosynthesis WHEP-TRS PF00458.20 KFP09958.1 - 1.2 9.3 3.8 0.35 11.0 0.4 1.9 2 0 0 2 2 2 0 WHEP-TRS domain L51_S25_CI-B8 PF05047.16 KFP09959.1 - 6.1e-18 64.5 0.0 7e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain mRNA_cap_C PF03919.15 KFP09959.1 - 0.097 13.3 0.0 0.11 13.2 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Arm PF00514.23 KFP09960.1 - 0.0021 18.1 31.7 0.96 9.6 0.1 8.3 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFP09960.1 - 0.15 12.1 3.7 6 7.0 0.5 3.3 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KFP09960.1 - 0.16 12.5 14.2 1.6 9.3 0.0 5.0 3 2 1 4 4 4 0 HEAT-like repeat DUF3361 PF11841.8 KFP09960.1 - 0.17 11.8 1.1 85 3.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) Proteasom_PSMB PF10508.9 KFP09960.1 - 0.19 10.2 0.2 0.57 8.6 0.2 1.7 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Nuc_sug_transp PF04142.15 KFP09961.1 - 2.6e-41 141.8 21.9 4.7e-41 141.0 21.8 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFP09961.1 - 1.6 8.9 41.1 0.12 12.5 11.4 2.4 2 1 0 2 2 2 0 EamA-like transporter family UAA PF08449.11 KFP09961.1 - 4.3 6.5 24.0 1.8 7.7 19.2 2.4 1 1 1 2 2 2 0 UAA transporter family TMEM173 PF15009.6 KFP09962.1 - 4.5e-101 337.8 0.1 6.7e-101 337.3 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 173 PRMT5_TIM PF17285.2 KFP09962.1 - 0.0025 17.0 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain DUF2157 PF09925.9 KFP09962.1 - 0.32 10.8 1.8 0.53 10.1 1.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) UQ_con PF00179.26 KFP09963.1 - 5.9e-35 120.0 0.2 6.2e-35 119.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP09963.1 - 0.019 15.3 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFP09963.1 - 0.074 12.8 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Ploopntkinase3 PF18751.1 KFP09964.1 - 3.1 7.7 5.9 0.22 11.4 0.8 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TNF PF00229.18 KFP09965.1 - 9e-32 109.7 0.6 1.5e-31 109.0 0.6 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Glyco_transf_52 PF07922.11 KFP09965.1 - 0.017 14.4 0.1 0.084 12.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 52 Glyco_trans_A_1 PF09318.10 KFP09966.1 - 0.18 11.5 0.6 0.41 10.3 0.6 1.5 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A DAGK_acc PF00609.19 KFP09967.1 - 1.1e-52 178.6 0.0 2.1e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP09967.1 - 1.3e-26 92.7 0.0 4.5e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFP09967.1 - 2.8e-19 68.7 25.4 6.8e-10 38.7 5.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 KFP09967.1 - 4.3e-17 62.0 1.0 9.2e-17 60.9 0.2 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFP09967.1 - 4.4e-16 59.3 0.7 1e-15 58.1 0.7 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 KFP09967.1 - 5.9e-16 58.7 0.6 1.3e-15 57.6 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KFP09967.1 - 0.00019 21.7 0.3 0.00041 20.6 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 KFP09967.1 - 0.0012 19.1 16.0 0.0054 17.0 5.7 2.6 2 0 0 2 2 2 2 C1 domain PH_11 PF15413.6 KFP09967.1 - 0.0065 16.9 2.0 0.0065 16.9 2.0 2.8 2 1 0 2 2 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KFP09967.1 - 0.03 14.4 0.1 0.089 12.9 0.1 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF883 PF05957.13 KFP09967.1 - 0.056 14.1 1.3 0.18 12.4 1.3 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SAM_4 PF18017.1 KFP09967.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Cdh1_DBD_1 PF18196.1 KFP09967.1 - 0.43 10.9 6.3 1.4 9.3 6.3 1.9 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 V_ATPase_I PF01496.19 KFP09967.1 - 8.7 4.1 7.1 16 3.2 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_5 PF07728.14 KFP09968.1 - 6.9e-101 333.8 0.0 2e-39 134.8 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP09968.1 - 4.1e-07 30.5 2.3 0.54 10.6 0.0 5.9 5 1 1 6 6 6 2 AAA ATPase domain AAA_3 PF07726.11 KFP09968.1 - 1.2e-05 25.2 0.0 0.0048 16.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFP09968.1 - 1.4e-05 25.5 0.2 0.027 14.9 0.0 3.9 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFP09968.1 - 6.4e-05 23.0 0.0 0.087 12.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain CbbQ_C PF08406.10 KFP09968.1 - 6.5e-05 23.1 0.0 0.68 10.2 0.0 2.7 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_7 PF12775.7 KFP09968.1 - 6.8e-05 22.5 0.1 0.49 9.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KFP09968.1 - 0.0002 21.7 0.0 0.78 10.0 0.0 4.1 3 1 0 3 3 3 1 AAA domain TniB PF05621.11 KFP09968.1 - 0.00038 19.9 0.0 0.72 9.2 0.0 3.0 2 0 0 2 2 2 2 Bacterial TniB protein AAA_lid_7 PF17867.1 KFP09968.1 - 0.00055 20.1 0.0 0.0078 16.4 0.1 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain Mg_chelatase PF01078.21 KFP09968.1 - 0.002 17.6 0.4 4.6 6.6 0.0 3.5 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFP09968.1 - 0.0027 17.8 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KFP09968.1 - 0.015 15.3 0.0 0.71 9.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KFP09968.1 - 0.027 14.7 0.3 2.3 8.5 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KFP09968.1 - 0.075 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP09968.1 - 0.17 12.5 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain 4HBT PF03061.22 KFP09969.1 - 4.8e-33 113.3 1.5 6e-16 58.6 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.25 KFP09969.1 - 0.00013 21.9 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain NINJA_B PF16136.5 KFP09969.1 - 5.2 7.5 11.2 1.1 9.7 3.9 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal ICMT PF04140.14 KFP09970.1 - 8.4e-35 119.1 0.1 1.3e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFP09970.1 - 3.8e-08 33.7 0.5 5.6e-08 33.1 0.5 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFP09970.1 - 0.015 14.8 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) zf-B_box PF00643.24 KFP09971.1 - 1.1e-09 38.2 8.8 9.7e-08 32.0 1.1 2.5 2 0 0 2 2 2 2 B-box zinc finger Thioredoxin_7 PF13899.6 KFP09971.1 - 0.0023 18.1 0.2 0.0077 16.4 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like MAD PF05557.13 KFP09971.1 - 0.0024 16.3 0.6 0.0024 16.3 0.6 2.1 2 0 0 2 2 2 1 Mitotic checkpoint protein IL10 PF00726.17 KFP09971.1 - 0.0051 16.3 3.0 0.0071 15.9 0.9 2.2 2 1 0 2 2 2 1 Interleukin 10 ARA70 PF12489.8 KFP09971.1 - 0.0076 16.4 0.8 0.0076 16.4 0.8 1.7 2 0 0 2 2 2 1 Nuclear coactivator zf-CHC2 PF01807.20 KFP09971.1 - 0.011 15.5 0.2 0.011 15.5 0.2 2.1 2 0 0 2 2 2 0 CHC2 zinc finger Mating_N PF12731.7 KFP09971.1 - 0.037 14.1 2.8 0.38 10.9 0.1 3.0 2 1 1 3 3 3 0 Mating-type protein beta 1 AAA_15 PF13175.6 KFP09971.1 - 0.16 11.7 1.6 0.16 11.6 0.4 1.6 2 0 0 2 2 2 0 AAA ATPase domain Fib_alpha PF08702.10 KFP09971.1 - 0.23 11.6 8.8 1.2 9.3 1.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 KFP09971.1 - 0.34 11.0 6.4 2.3 8.3 2.3 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KFP09971.1 - 0.86 9.6 3.6 2.9 7.9 0.9 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KFP09971.1 - 1 8.9 5.9 0.37 10.3 1.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit ParB PF08775.10 KFP09971.1 - 1.4 9.5 6.1 14 6.1 0.3 2.4 2 0 0 2 2 2 0 ParB family Muted PF14942.6 KFP09971.1 - 1.9 8.8 10.7 0.44 10.9 4.1 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein FYVE PF01363.21 KFP09971.1 - 2.6 8.3 8.6 1.5 9.0 6.0 2.0 1 1 0 1 1 1 0 FYVE zinc finger DUF1664 PF07889.12 KFP09971.1 - 4.2 7.4 8.0 4.3 7.4 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-C4pol PF14260.6 KFP09971.1 - 6.1 7.4 17.4 1.6 9.3 5.2 3.7 3 1 1 4 4 3 0 C4-type zinc-finger of DNA polymerase delta V-SNARE PF05008.15 KFP09971.1 - 6.2 7.3 11.4 6.3 7.3 3.7 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DivIVA PF05103.13 KFP09971.1 - 7.2 6.7 17.1 22 5.1 0.8 2.8 2 1 0 2 2 2 0 DivIVA protein Ribosomal_S27e PF01667.17 KFP09971.1 - 7.6 6.3 10.4 13 5.6 0.2 3.1 3 0 0 3 3 3 0 Ribosomal protein S27 DUF1086 PF06461.11 KFP09972.1 - 9.2e-62 207.0 0.0 4.1e-61 204.9 0.0 2.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.23 KFP09972.1 - 1.1e-61 208.5 0.1 1.1e-61 208.5 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain CHDCT2 PF08074.11 KFP09972.1 - 6.8e-33 114.2 0.8 1.8e-32 112.8 0.8 1.7 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1087 PF06465.13 KFP09972.1 - 6.9e-26 90.1 5.7 6.9e-26 90.1 5.7 3.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 KFP09972.1 - 1.3e-25 89.1 0.4 3.4e-25 87.7 0.4 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain Chromo PF00385.24 KFP09972.1 - 9.3e-17 60.7 7.4 8.5e-12 44.8 1.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KFP09972.1 - 2.5e-11 43.3 6.5 6.9e-11 41.9 6.5 1.8 1 0 0 1 1 1 1 PHD-finger Helicase_C PF00271.31 KFP09972.1 - 1.3e-09 38.4 0.0 5.6e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP09972.1 - 2e-08 34.5 0.0 2e-08 34.5 0.0 2.4 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-HC5HC2H PF13771.6 KFP09972.1 - 0.0081 16.4 0.3 0.024 14.9 0.3 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain AAA_22 PF13401.6 KFP09972.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zn_ribbon_17 PF17120.5 KFP09972.1 - 0.31 10.7 7.4 0.71 9.5 7.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FeS_assembly_P PF01883.19 KFP09973.1 - 6e-06 26.3 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein MRG PF05712.13 KFP09974.1 - 3.3e-54 183.2 0.7 6.4e-54 182.3 0.7 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFP09974.1 - 8.6e-11 41.6 2.0 1e-08 34.9 0.1 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Keratin PF02422.16 KFP09975.1 - 5.9e-34 115.6 7.4 5.9e-34 115.6 7.4 2.0 1 1 1 2 2 2 1 Keratin DUF35_N PF12172.8 KFP09975.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3432 PF11914.8 KFP09975.1 - 0.11 12.7 5.6 0.17 12.2 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP09976.1 - 5e-36 122.3 13.3 5e-36 122.3 13.3 2.8 1 1 1 2 2 2 1 Keratin Cornifin PF02389.15 KFP09976.1 - 0.0072 16.5 4.9 0.0083 16.3 4.9 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3432 PF11914.8 KFP09976.1 - 0.84 9.9 10.8 1.6 9.0 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP09977.1 - 1.9e-37 126.8 13.3 2.1e-37 126.7 13.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP09978.1 - 2.3e-38 129.8 15.5 2.6e-38 129.6 15.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP09979.1 - 1.7e-35 120.6 12.3 1.8e-35 120.5 12.3 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP09980.1 - 4.4e-36 122.4 12.7 4.8e-36 122.3 12.7 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP09982.1 - 4.4e-39 132.1 9.3 4.7e-39 132.0 9.3 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP09982.1 - 0.025 13.5 0.1 0.026 13.4 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP09984.1 - 1.1e-39 134.0 10.6 1.2e-39 133.9 10.6 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP09984.1 - 0.11 11.3 0.2 0.12 11.2 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Keratin PF02422.16 KFP09986.1 - 1.1e-39 134.0 10.6 1.2e-39 133.9 10.6 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP09986.1 - 0.11 11.3 0.2 0.12 11.2 0.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Integrin_alpha2 PF08441.12 KFP09987.1 - 2.2e-31 109.3 0.0 2.4e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Integrin alpha PCuAC PF04314.13 KFP09987.1 - 0.1 12.4 0.0 0.52 10.1 0.0 2.1 1 1 1 2 2 2 0 Copper chaperone PCu(A)C Frizzled PF01534.17 KFP09988.1 - 7.7e-142 472.1 19.2 9.7e-142 471.8 19.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP09988.1 - 6.7e-34 116.8 3.8 1.5e-33 115.7 3.8 1.6 1 0 0 1 1 1 1 Fz domain RPN6_N PF18055.1 KFP09989.1 - 3.2e-19 69.4 0.1 3.4e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain SEN1_N PF12726.7 KFP09989.1 - 0.033 12.4 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal Pkinase PF00069.25 KFP09990.1 - 1.6e-45 155.6 0.0 2.6e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09990.1 - 2e-28 99.4 0.0 3.1e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP09990.1 - 1.5e-05 24.0 0.0 4.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase FH2 PF02181.23 KFP09991.1 - 2e-107 359.5 25.3 3.9e-103 345.5 7.2 3.9 3 1 1 4 4 4 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFP09991.1 - 1.1e-39 136.2 8.5 3.1e-39 134.6 8.5 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFP09991.1 - 1.2e-20 73.8 18.3 7.8e-12 45.1 1.4 4.3 5 0 0 5 5 5 2 Diaphanous GTPase-binding Domain DUF4349 PF14257.6 KFP09991.1 - 0.0032 17.0 2.4 0.0088 15.5 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LXG PF04740.12 KFP09991.1 - 0.028 14.2 6.0 0.014 15.1 2.7 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily HTH_7 PF02796.15 KFP09991.1 - 0.048 13.8 0.6 14 5.8 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain of resolvase TraK PF06586.11 KFP09991.1 - 0.088 12.5 1.6 11 5.6 0.6 2.4 2 0 0 2 2 2 0 TraK protein Mis12 PF05859.12 KFP09991.1 - 0.1 12.7 3.5 0.47 10.5 3.5 2.1 1 0 0 1 1 1 0 Mis12 protein Ribosomal_L29 PF00831.23 KFP09991.1 - 0.3 11.1 4.9 0.13 12.2 0.3 2.8 2 0 0 2 2 2 0 Ribosomal L29 protein Peptidase_M13_N PF05649.13 KFP09991.1 - 0.38 10.4 3.8 0.73 9.5 0.3 2.3 2 0 0 2 2 2 0 Peptidase family M13 Snapin_Pallidin PF14712.6 KFP09991.1 - 0.47 10.9 8.9 1.3 9.5 4.3 3.1 2 0 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 KFP09991.1 - 0.65 10.5 14.2 0.94 10.0 6.8 3.2 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapD PF07072.11 KFP09991.1 - 0.75 9.5 11.2 0.19 11.4 6.5 2.4 2 0 0 2 2 2 0 Cell division protein FNIP_M PF14637.6 KFP09991.1 - 1.2 9.1 5.5 2.5 8.1 0.3 3.2 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Phage_GP20 PF06810.11 KFP09991.1 - 1.3 8.8 11.3 1 9.2 4.2 3.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 BST2 PF16716.5 KFP09991.1 - 1.5 9.5 7.4 1.1 9.9 2.5 3.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4208 PF13907.6 KFP09991.1 - 2.4 8.7 4.8 23 5.5 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) DUF4446 PF14584.6 KFP09991.1 - 2.4 8.1 5.9 25 4.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) UPF0122 PF04297.14 KFP09991.1 - 7.2 6.9 9.7 0.26 11.5 2.1 2.7 3 0 0 3 3 2 0 Putative helix-turn-helix protein, YlxM / p13 like Pkinase PF00069.25 KFP09992.1 - 1.5e-23 83.5 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP09992.1 - 4.5e-07 29.4 0.0 6.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP09992.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NMT_C PF02799.15 KFP09993.1 - 7.8e-84 280.4 0.1 1.2e-83 279.8 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFP09993.1 - 6.8e-75 250.3 0.0 1.3e-74 249.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KFP09993.1 - 0.0001 22.5 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFP09993.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4276 PF14103.6 KFP09993.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) PX PF00787.24 KFP09993.1 - 0.16 12.0 0.9 0.44 10.6 0.9 1.8 1 0 0 1 1 1 0 PX domain SR-25 PF10500.9 KFP09993.1 - 1.6 8.2 6.8 2.5 7.6 6.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CoaE PF01121.20 KFP09994.1 - 1e-61 207.7 0.0 1.4e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KFP09994.1 - 0.00014 22.4 0.2 0.00095 19.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFP09994.1 - 0.0016 18.6 0.0 0.0054 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFP09994.1 - 0.0093 16.4 0.1 0.2 12.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain HicA_toxin PF07927.12 KFP09994.1 - 0.016 15.2 0.1 0.3 11.2 0.1 2.5 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, AAA_28 PF13521.6 KFP09994.1 - 0.03 14.6 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain C1q PF00386.21 KFP09995.1 - 1.9e-17 63.6 0.0 2.1e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 C1q domain SWIB PF02201.18 KFP09996.1 - 5.8e-21 74.2 0.1 1.6e-20 72.7 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain UBA2_C PF16195.5 KFP09997.1 - 0.0033 18.1 10.5 0.0051 17.5 3.0 2.2 2 0 0 2 2 2 2 SUMO-activating enzyme subunit 2 C-terminus Integrin_beta PF00362.18 KFP09998.1 - 7e-117 389.4 0.0 1e-116 388.9 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFP09998.1 - 4.6e-21 74.2 1.6 1.1e-20 73.0 1.6 1.7 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.12 KFP09998.1 - 1.5e-17 63.8 9.1 1.5e-17 63.8 9.1 5.0 4 2 0 5 5 5 1 Integrin beta tail domain PSI_integrin PF17205.3 KFP09998.1 - 3.3e-15 55.5 6.5 3.3e-15 55.5 6.5 4.8 5 0 0 5 5 5 1 Integrin plexin domain I-EGF_1 PF18372.1 KFP09998.1 - 8.9e-08 32.1 11.6 8.9e-08 32.1 11.6 6.5 7 0 0 7 7 7 2 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFP09998.1 - 3.7e-05 24.0 106.7 0.0014 18.9 16.0 7.4 6 1 1 7 7 7 4 EGF-like domain FAD_binding_3 PF01494.19 KFP09999.1 - 9.9e-22 77.6 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFP09999.1 - 2.8e-05 24.2 1.7 3.9e-05 23.8 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP09999.1 - 3.7e-05 23.5 0.1 0.00026 20.7 0.4 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KFP09999.1 - 0.00017 20.8 0.1 0.11 11.5 0.0 2.4 2 1 0 2 2 2 2 Squalene epoxidase 3HCDH_N PF02737.18 KFP09999.1 - 0.0012 18.7 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFP09999.1 - 0.0039 16.5 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP09999.1 - 0.0041 17.6 0.2 0.0086 16.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFP09999.1 - 0.054 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KFP09999.1 - 0.087 11.9 0.2 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KFP09999.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_I PF03899.15 KFP09999.1 - 0.25 11.7 0.5 0.52 10.7 0.1 1.7 2 0 0 2 2 2 0 ATP synthase I chain DUF4587 PF15248.6 KFP10000.1 - 1.8e-32 111.9 12.5 1.8e-32 111.9 12.5 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4587) COG2 PF06148.11 KFP10000.1 - 0.086 12.9 0.6 0.17 12.0 0.6 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 APH PF01636.23 KFP10000.1 - 0.42 10.5 8.1 3.6 7.4 7.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Trimer_CC PF08954.11 KFP10001.1 - 0.0071 15.9 5.9 0.016 14.7 5.9 1.6 1 0 0 1 1 1 1 Trimerisation motif FAM184 PF15665.5 KFP10001.1 - 0.085 12.6 30.6 0.096 12.5 15.6 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PACT_coil_coil PF10495.9 KFP10003.1 - 2e-27 95.6 0.0 3.1e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ThiF PF00899.21 KFP10006.1 - 4e-67 226.1 0.0 5e-47 160.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFP10006.1 - 5.4e-55 187.0 0.0 7.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFP10006.1 - 1.2e-25 89.5 0.0 2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KFP10006.1 - 1.7e-15 56.9 0.1 5.3e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 KFP10006.1 - 0.028 14.9 0.1 7.8 7.0 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KFP10006.1 - 0.093 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP10006.1 - 0.13 12.8 0.2 0.59 10.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAG1 PF05454.11 KFP10008.1 - 2.6e-153 509.5 7.4 3.9e-153 508.9 7.4 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) a_DG1_N2 PF18424.1 KFP10008.1 - 1.5e-67 225.3 0.1 2.4e-67 224.6 0.1 1.4 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 TMEM154 PF15102.6 KFP10008.1 - 0.0028 17.6 0.1 0.0028 17.6 0.1 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF4064 PF13273.6 KFP10008.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Peptidase_S9 PF00326.21 KFP10009.1 - 3.5e-35 121.4 0.0 5.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFP10009.1 - 9.1e-13 48.4 0.2 1.8e-08 34.3 0.6 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP10009.1 - 2.1e-10 40.3 0.0 2.8e-05 23.5 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFP10009.1 - 9.4e-07 28.6 0.0 5.2e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFP10009.1 - 1e-06 28.8 0.1 4.1e-06 26.8 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFP10009.1 - 1.7e-06 27.8 0.0 0.015 14.9 0.0 2.3 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 KFP10009.1 - 2.3e-05 23.5 0.0 3.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KFP10009.1 - 0.00039 21.1 10.2 0.00039 21.1 10.2 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KFP10009.1 - 0.0045 16.9 0.0 0.0093 15.9 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.9 KFP10009.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.13 KFP10009.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KFP10009.1 - 0.12 11.9 1.9 0.48 9.9 1.9 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 KFP10009.1 - 0.19 10.4 0.0 4.7 5.8 0.1 2.6 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) zf-piccolo PF05715.13 KFP10010.1 - 5.1e-57 189.9 34.9 1.2e-29 102.2 13.0 2.7 2 0 0 2 2 2 2 Piccolo Zn-finger FYVE_2 PF02318.16 KFP10010.1 - 2.3e-05 24.6 15.8 0.00024 21.3 3.1 4.0 4 0 0 4 4 4 2 FYVE-type zinc finger IBR PF01485.21 KFP10010.1 - 0.18 12.0 16.2 0.33 11.2 4.2 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain T3SSipB PF16535.5 KFP10011.1 - 0.00061 20.3 0.2 0.00061 20.3 0.2 3.3 3 1 1 4 4 3 1 Type III cell invasion protein SipB DUF3958 PF13125.6 KFP10011.1 - 0.0022 18.2 4.2 0.0022 18.2 4.2 3.6 2 1 1 3 3 2 1 Protein of unknown function (DUF3958) Filament PF00038.21 KFP10011.1 - 0.0048 16.5 25.4 0.008 15.8 25.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein BRE1 PF08647.11 KFP10011.1 - 0.022 14.8 15.2 0.022 14.8 15.2 3.2 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 KFP10011.1 - 0.072 12.4 38.6 0.19 11.0 13.5 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Flagellin_C PF00700.21 KFP10011.1 - 0.095 13.1 1.6 0.18 12.2 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Spc7 PF08317.11 KFP10011.1 - 0.13 11.1 35.3 0.047 12.6 12.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KFP10011.1 - 0.14 12.8 34.8 0.17 12.5 9.7 3.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 EzrA PF06160.12 KFP10011.1 - 0.16 10.1 26.2 0.04 12.1 7.7 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA APG17 PF04108.12 KFP10011.1 - 0.31 10.1 18.6 0.64 9.1 4.7 2.5 1 1 1 2 2 2 0 Autophagy protein Apg17 Laminin_II PF06009.12 KFP10011.1 - 0.36 10.8 21.4 0.067 13.2 6.4 2.5 2 0 0 2 2 2 0 Laminin Domain II HMMR_N PF15905.5 KFP10011.1 - 0.48 9.8 39.8 0.87 9.0 12.7 2.6 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Rx_N PF18052.1 KFP10011.1 - 0.48 10.7 18.4 2.3 8.6 1.6 3.9 3 0 0 3 3 3 0 Rx N-terminal domain DUF812 PF05667.11 KFP10011.1 - 0.56 9.0 29.4 0.96 8.3 29.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 KFP10011.1 - 0.75 9.9 32.7 0.081 13.1 10.5 2.8 2 1 0 2 2 2 0 Tropomyosin like WEMBL PF05701.11 KFP10011.1 - 1.4 7.5 31.2 10 4.7 22.5 2.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light KASH_CCD PF14662.6 KFP10011.1 - 1.8 8.4 39.4 2.5 7.9 26.2 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH NBP1 PF08537.10 KFP10011.1 - 2.2 7.6 20.1 3.8 6.8 20.1 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF1664 PF07889.12 KFP10011.1 - 2.2 8.3 24.7 0.23 11.5 6.7 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KFP10011.1 - 2.3 8.4 30.7 11 6.2 21.4 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DegS PF05384.11 KFP10011.1 - 2.3 7.7 28.9 3.5 7.1 5.5 3.2 1 1 2 3 3 3 0 Sensor protein DegS Golgin_A5 PF09787.9 KFP10011.1 - 2.4 7.6 33.8 9.6 5.6 13.7 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 Colicin PF01024.19 KFP10011.1 - 3.3 7.6 10.3 0.46 10.4 4.2 2.1 2 0 0 2 2 2 0 Colicin pore forming domain MAD PF05557.13 KFP10011.1 - 3.8 5.8 34.7 14 3.9 33.2 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein DASH_Duo1 PF08651.10 KFP10011.1 - 4.3 7.2 9.8 1.6 8.6 2.3 3.4 2 2 1 3 3 3 0 DASH complex subunit Duo1 WXG100 PF06013.12 KFP10011.1 - 4.4 7.6 9.0 0.45 10.8 0.4 3.2 3 1 0 3 3 2 0 Proteins of 100 residues with WXG Fez1 PF06818.15 KFP10011.1 - 4.4 7.7 31.7 2 8.8 9.2 2.4 1 1 1 2 2 2 0 Fez1 MscS_porin PF12795.7 KFP10011.1 - 4.5 6.8 26.9 1 8.8 5.8 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 KFP10011.1 - 4.5 7.5 24.0 1.2 9.3 9.4 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 KFP10011.1 - 4.5 7.3 40.4 19 5.2 12.0 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1759 PF03564.15 KFP10011.1 - 4.8 7.1 9.7 5.7 6.9 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) IFT57 PF10498.9 KFP10011.1 - 4.8 6.1 27.5 0.17 10.8 9.5 2.2 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 KFP10011.1 - 5.8 7.1 36.2 22 5.3 11.5 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 MCPsignal PF00015.21 KFP10011.1 - 8.3 6.2 8.7 0.91 9.3 1.1 2.5 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RP-C_C PF11800.8 KFP10011.1 - 9.2 6.3 12.0 2.8e+02 1.5 11.8 2.4 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF87 PF01935.17 KFP10011.1 - 9.7 6.2 18.7 1.8 8.6 5.0 2.2 1 1 1 2 2 2 0 Helicase HerA, central domain Occludin_ELL PF07303.13 KFP10011.1 - 9.7 7.0 19.9 4.3 8.1 5.4 2.9 2 1 0 2 2 2 0 Occludin homology domain Pkinase PF00069.25 KFP10012.1 - 7e-50 169.8 0.0 8.7e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10012.1 - 5.1e-20 71.8 0.0 6.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP10012.1 - 0.00011 21.7 0.1 0.011 15.1 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFP10012.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf_CCCH_4 PF18345.1 KFP10013.1 - 6.5e-17 61.0 24.5 4.7e-06 26.5 5.7 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KFP10013.1 - 5.2e-14 51.7 15.9 0.00012 21.9 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFP10013.1 - 1.3e-12 47.2 19.7 1.2e-09 37.7 2.6 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 KFP10013.1 - 0.00035 21.2 0.5 0.00035 21.2 0.5 5.0 3 1 2 5 5 5 3 Torus domain zf-CCCH_2 PF14608.6 KFP10013.1 - 0.011 16.1 22.8 1.1 9.8 3.4 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP10013.1 - 0.12 12.6 12.6 0.37 11.0 4.0 2.4 1 1 1 2 2 2 0 Zinc-finger containing family Ank_5 PF13857.6 KFP10015.1 - 2.7e-08 33.9 0.1 3.2e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP10015.1 - 1.3e-07 32.1 0.0 1.7e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10015.1 - 3.6e-07 30.6 0.3 0.00011 22.6 0.1 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP10015.1 - 6.2e-07 29.6 0.3 3.5e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFP10015.1 - 2e-06 27.7 0.2 5.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat SPRY PF00622.28 KFP10016.1 - 2e-26 92.4 0.1 3.9e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFP10016.1 - 7.9e-05 22.4 4.8 7.9e-05 22.4 4.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP10016.1 - 0.0067 16.3 7.7 0.018 14.9 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP10016.1 - 0.0083 16.0 5.2 0.024 14.5 5.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP10016.1 - 0.034 14.5 5.0 0.084 13.2 5.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KFP10016.1 - 0.34 10.9 4.4 0.99 9.4 4.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP10016.1 - 0.4 10.8 6.4 0.87 9.7 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KFP10016.1 - 6.5 6.7 10.6 2.5 8.1 6.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 NTP_transferase PF00483.23 KFP10017.1 - 8.2e-23 81.3 0.0 1.6e-22 80.3 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KFP10017.1 - 1.3e-09 37.4 10.7 2.8e-09 36.3 4.4 3.2 2 1 1 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFP10017.1 - 2.4e-05 24.0 3.2 2.4e-05 24.0 3.2 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFP10017.1 - 0.006 14.8 0.4 0.0084 14.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFP10017.1 - 0.23 10.4 0.0 0.5 9.2 0.0 1.6 1 1 0 1 1 1 0 L-fucokinase IPK PF03770.16 KFP10018.1 - 1.1e-64 217.9 0.0 1.7e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Sulfotransfer_1 PF00685.27 KFP10019.1 - 1.4e-64 218.1 0.0 2e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP10019.1 - 1.6e-08 35.2 0.0 2.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Actin PF00022.19 KFP10021.1 - 2.1e-112 375.7 0.0 7.9e-112 373.8 0.0 1.7 1 1 0 1 1 1 1 Actin UCH PF00443.29 KFP10024.1 - 4e-48 164.2 1.4 4.7e-48 163.9 1.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP10024.1 - 1.4e-22 80.7 1.1 2e-22 80.2 1.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2913 PF11140.8 KFP10024.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Benyvirus_14KDa PF07255.11 KFP10024.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.5 3 0 0 3 3 3 0 Benyvirus 14KDa protein DZR PF12773.7 KFP10024.1 - 7.2 6.7 9.1 6.5 6.9 3.2 3.2 2 1 0 2 2 2 0 Double zinc ribbon tRNA-synt_2b PF00587.25 KFP10025.1 - 1.6e-14 54.3 0.0 2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cytochrom_C552 PF02335.15 KFP10025.1 - 0.023 13.6 0.2 0.03 13.3 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c552 Keratin PF02422.16 KFP10027.1 - 8.7e-35 118.3 14.7 9.5e-35 118.2 14.7 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP10027.1 - 0.37 9.6 0.3 0.38 9.6 0.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FUN14 PF04930.15 KFP10029.1 - 1.5e-29 102.2 2.7 1.9e-29 101.9 2.7 1.1 1 0 0 1 1 1 1 FUN14 family EutA PF06277.11 KFP10029.1 - 0.053 12.4 0.1 0.063 12.1 0.1 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA SPC12 PF06645.13 KFP10029.1 - 0.56 10.3 2.9 0.96 9.6 0.9 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1126 PF06565.12 KFP10030.1 - 9.2e-102 334.0 3.2 9.1e-32 109.0 0.1 4.3 3 1 1 4 4 4 4 DUF1126 PH-like domain DUF5580 PF17743.1 KFP10030.1 - 0.03 12.9 0.1 0.043 12.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Cys_knot PF00007.22 KFP10031.1 - 2.4e-06 27.8 13.0 3.5e-06 27.3 13.0 1.3 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFP10031.1 - 6.5e-06 26.2 9.7 7.9e-06 25.9 9.7 1.1 1 0 0 1 1 1 1 DAN domain Amino_oxidase PF01593.24 KFP10032.1 - 2.4e-74 251.3 0.0 2.8e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP10032.1 - 1.1e-07 31.9 0.0 3.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFP10033.1 - 9.1e-67 226.3 0.0 1.1e-66 226.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP10033.1 - 1.8e-07 31.3 0.0 5.9e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 7tm_1 PF00001.21 KFP10035.1 - 8.2e-17 61.4 26.5 3.8e-10 39.6 2.7 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Renin_r PF07850.14 KFP10035.1 - 0.0049 17.4 1.6 0.0049 17.4 1.6 2.2 2 1 0 2 2 2 1 Renin receptor-like protein Virul_fac_BrkB PF03631.15 KFP10035.1 - 0.17 11.5 6.6 0.3 10.7 0.7 2.4 2 0 0 2 2 2 0 Virulence factor BrkB RDD PF06271.12 KFP10035.1 - 0.28 11.4 10.1 0.81 9.9 2.2 2.3 2 0 0 2 2 2 0 RDD family DEAD PF00270.29 KFP10036.1 - 1.1e-50 171.8 0.0 3.9e-50 170.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP10036.1 - 1.1e-31 109.5 0.0 2.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP10036.1 - 0.0046 17.0 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KFP10036.1 - 0.018 13.8 0.0 0.037 12.8 0.0 1.4 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ribosomal_L2_C PF03947.18 KFP10037.1 - 7.9e-49 165.1 3.0 1.1e-48 164.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFP10037.1 - 3e-08 33.5 0.0 1.2e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain UCH PF00443.29 KFP10038.1 - 5.6e-50 170.2 0.4 3.3e-49 167.7 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP10038.1 - 3.1e-27 96.0 0.0 9.1e-26 91.2 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1722 PF08349.11 KFP10038.1 - 0.055 13.8 0.0 15 5.9 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Vps23_core PF09454.10 KFP10038.1 - 0.07 13.1 0.5 0.48 10.4 0.1 2.8 3 0 0 3 3 3 0 Vps23 core domain FAST_1 PF06743.15 KFP10038.1 - 0.11 12.5 0.2 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Cas9_a PF18470.1 KFP10038.1 - 0.18 11.3 0.7 0.46 10.0 0.6 1.7 1 1 0 1 1 1 0 Cas9 alpha-helical lobe domain Med14 PF08638.11 KFP10039.1 - 9.3e-52 175.2 0.0 2.4e-51 173.9 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit MED14 RE_SinI PF09570.10 KFP10039.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease Renin_r PF07850.14 KFP10040.1 - 3.9e-37 126.8 1.3 6e-37 126.2 1.3 1.3 1 0 0 1 1 1 1 Renin receptor-like protein DUF2273 PF10031.9 KFP10040.1 - 0.089 12.8 1.0 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Glycophorin_A PF01102.18 KFP10040.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A BCOR PF15808.5 KFP10041.1 - 2.6e-78 263.2 27.0 2.6e-78 263.2 27.0 2.6 2 0 0 2 2 2 1 BCL-6 co-repressor, non-ankyrin-repeat region PUFD PF16553.5 KFP10041.1 - 3.6e-53 178.6 0.6 1e-52 177.1 0.6 1.9 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Ank_2 PF12796.7 KFP10041.1 - 1.7e-14 54.1 0.3 7.8e-14 52.0 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP10041.1 - 1.1e-13 50.0 0.8 7.7e-05 22.8 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP10041.1 - 2.7e-12 46.7 1.9 2.3e-08 34.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP10041.1 - 6.7e-12 45.7 5.3 3.5e-06 27.5 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP10041.1 - 1.6e-08 34.6 0.6 0.019 15.4 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeat Tetraspanin PF00335.20 KFP10047.1 - 2.2e-43 148.6 5.6 2.4e-43 148.5 5.6 1.0 1 0 0 1 1 1 1 Tetraspanin family OTCace PF00185.24 KFP10049.1 - 6.3e-52 175.8 0.0 9e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KFP10049.1 - 1.5e-43 148.4 0.0 3.4e-43 147.2 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RCC1 PF00415.18 KFP10050.1 - 3.7e-74 245.2 16.6 8.4e-13 48.7 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP10050.1 - 9.2e-41 136.9 21.2 1.8e-08 34.0 0.1 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 KFP10050.1 - 0.0061 16.5 6.7 1.5 8.8 0.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP10050.1 - 0.008 16.1 0.2 7.7 6.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif DUF1921 PF09081.10 KFP10050.1 - 0.18 12.1 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) DUF4174 PF13778.6 KFP10053.1 - 5.5e-31 107.5 0.0 7.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.16 KFP10053.1 - 1e-28 99.5 0.0 1.8e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 HYR domain Sushi PF00084.20 KFP10053.1 - 7.4e-25 87.3 26.8 5e-11 43.0 3.9 3.4 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) C2 PF00168.30 KFP10054.1 - 1e-44 151.0 0.7 7.7e-23 80.7 0.2 2.3 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KFP10054.1 - 1.3e-18 67.3 9.7 3.1e-18 66.1 9.7 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger PI3K_C2 PF00792.24 KFP10054.1 - 0.059 13.3 0.3 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Rep_fac-A_C PF08646.10 KFP10054.1 - 0.64 9.8 3.5 1.6 8.5 3.5 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-Sec23_Sec24 PF04810.15 KFP10054.1 - 2.8 8.0 6.2 8.6 6.5 6.2 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Tctex-1 PF03645.13 KFP10055.1 - 1.5e-31 108.7 2.7 1.6e-31 108.6 2.7 1.0 1 0 0 1 1 1 1 Tctex-1 family NAD_binding_6 PF08030.12 KFP10056.1 - 6e-37 127.2 0.0 1e-36 126.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFP10056.1 - 1.7e-24 86.3 7.5 1.7e-24 86.3 7.5 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFP10056.1 - 6.6e-22 77.7 0.0 1.6e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KFP10056.1 - 0.00014 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFP10056.1 - 0.023 15.4 0.0 0.11 13.1 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain LANC_like PF05147.13 KFP10057.1 - 1.7e-57 194.6 0.0 2.1e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 KFP10057.1 - 0.021 14.3 1.0 1.7 8.1 0.2 2.3 1 1 1 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KFP10057.1 - 0.08 11.4 0.0 0.34 9.3 0.0 1.6 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 ASH PF15780.5 KFP10058.1 - 2.7e-09 37.1 6.9 0.011 15.9 0.3 5.7 6 1 1 7 7 7 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KFP10058.1 - 2.7e-08 33.6 1.4 0.051 13.4 0.1 4.5 5 0 0 5 5 5 3 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KFP10058.1 - 0.00026 21.2 0.7 0.0096 16.2 0.1 3.2 3 0 0 3 3 3 1 Transmembrane protein 131-like WT1 PF02165.15 KFP10058.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Wilm's tumour protein Gal-bind_lectin PF00337.22 KFP10059.1 - 0.026 14.1 0.0 0.1 12.1 0.0 1.9 2 1 1 3 3 3 0 Galactoside-binding lectin Arrestin_N PF00339.29 KFP10059.1 - 0.04 14.0 0.1 0.079 13.0 0.0 1.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain CAMSAP_CH PF11971.8 KFP10060.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Membr_traf_MHD PF10540.9 KFP10060.1 - 0.0059 16.8 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain CH PF00307.31 KFP10060.1 - 0.022 14.9 0.1 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 Calponin homology (CH) domain HTH_9 PF08221.11 KFP10060.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ASH PF15780.5 KFP10062.1 - 0.0049 17.1 0.0 0.0078 16.4 0.0 1.4 1 1 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP10062.1 - 0.022 15.0 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 131-like Glu_cys_ligase PF04262.14 KFP10063.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Git3 PF11710.8 KFP10065.1 - 0.016 15.0 1.1 0.018 14.8 1.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 L_HMGIC_fpl PF10242.9 KFP10065.1 - 0.017 15.3 3.8 0.026 14.8 3.8 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFP10065.1 - 0.018 14.8 10.4 0.024 14.4 10.4 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 KFP10065.1 - 0.077 12.9 3.6 0.1 12.5 3.6 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ApoO PF09769.9 KFP10065.1 - 0.19 11.7 1.5 0.26 11.3 1.5 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3525 PF12039.8 KFP10065.1 - 0.2 10.3 0.3 0.24 10.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) SUR7 PF06687.12 KFP10065.1 - 0.45 10.1 7.8 0.6 9.7 7.8 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF2721 PF11026.8 KFP10065.1 - 0.73 9.7 6.4 1.1 9.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) 2TM PF13239.6 KFP10065.1 - 0.81 10.0 3.9 0.28 11.5 1.4 1.6 1 1 1 2 2 2 0 2TM domain Yip1 PF04893.17 KFP10065.1 - 1.1 8.9 12.6 1.7 8.3 12.6 1.3 1 1 0 1 1 1 0 Yip1 domain HALZ PF02183.18 KFP10074.1 - 0.0045 17.2 8.4 0.085 13.1 3.8 2.4 2 0 0 2 2 2 2 Homeobox associated leucine zipper APG6_N PF17675.1 KFP10074.1 - 0.007 16.9 0.6 0.011 16.3 0.6 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region LRRFIP PF09738.9 KFP10074.1 - 0.015 14.8 0.9 0.015 14.8 0.9 1.3 1 0 0 1 1 1 0 LRRFIP family YabA PF06156.13 KFP10074.1 - 0.022 15.4 1.8 0.075 13.7 0.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA SOGA PF11365.8 KFP10074.1 - 0.034 15.3 2.1 0.078 14.1 2.1 1.8 1 1 0 1 1 1 0 Protein SOGA bZIP_1 PF00170.21 KFP10074.1 - 0.1 12.7 0.9 0.1 12.7 0.9 1.9 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KFP10074.1 - 0.88 10.1 10.1 1.7 9.1 4.8 2.5 3 0 0 3 3 3 0 Cell division protein ZapB FGGY_N PF00370.21 KFP10075.1 - 1e-79 267.6 0.0 1.4e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFP10075.1 - 3.4e-64 216.2 0.9 4.4e-64 215.9 0.2 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4569 PF15133.6 KFP10077.1 - 1.4e-103 346.8 6.6 1.5e-103 346.6 6.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) VWC PF00093.18 KFP10084.1 - 1.5e-26 92.5 61.2 1.2e-09 38.4 10.2 3.8 4 0 0 4 4 4 3 von Willebrand factor type C domain Amnionless PF14828.6 KFP10084.1 - 0.00024 20.1 5.9 0.00024 20.1 5.9 3.1 1 1 2 3 3 3 3 Amnionless DUF1496 PF07383.12 KFP10084.1 - 0.0088 15.6 2.3 2 8.1 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) TMEM164 PF14808.6 KFP10085.1 - 1.4e-117 391.6 8.6 1.6e-117 391.3 8.6 1.0 1 0 0 1 1 1 1 TMEM164 family DUF1184 PF06683.11 KFP10085.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) AMP-binding PF00501.28 KFP10086.1 - 3.8e-107 358.5 0.0 5e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP10086.1 - 1.8e-06 28.9 0.0 5.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NTF2 PF02136.20 KFP10087.1 - 7.3e-31 107.2 0.5 8.4e-31 107.0 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 KFP10087.1 - 0.072 13.7 0.0 0.086 13.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain ODR4-like PF14778.6 KFP10087.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like Peptidase_C54 PF03416.19 KFP10088.1 - 3.4e-102 341.6 0.0 4.1e-102 341.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ank_5 PF13857.6 KFP10089.1 - 2.6e-41 139.1 9.3 4.3e-14 52.4 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP10089.1 - 5e-36 122.6 4.7 8.3e-13 48.6 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP10089.1 - 1.6e-35 120.0 5.0 2.2e-08 34.2 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KFP10089.1 - 2.7e-32 107.2 1.4 8.6e-08 31.9 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 KFP10089.1 - 8.3e-32 109.6 1.6 5.8e-16 58.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF249 PF03158.13 KFP10089.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Multigene family 530 protein DUF4799 PF16056.5 KFP10089.1 - 0.094 11.9 0.1 0.18 10.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4799) AMNp_N PF10423.9 KFP10089.1 - 0.18 11.4 0.0 2.7 7.6 0.0 2.2 2 1 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus V-set PF07686.17 KFP10090.1 - 2.2e-23 82.5 5.1 7e-22 77.7 0.4 3.1 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP10090.1 - 5.6e-22 78.1 2.1 6.2e-10 39.6 0.6 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP10090.1 - 2.7e-14 53.0 0.1 2.9e-06 27.2 0.3 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP10090.1 - 6.1e-12 45.5 1.4 6e-08 32.8 0.3 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP10090.1 - 8.7e-11 42.0 5.4 0.00015 22.0 1.4 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Shisa PF13908.6 KFP10090.1 - 0.00063 20.0 0.4 0.0014 18.9 0.4 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MscL PF01741.18 KFP10090.1 - 0.0012 19.1 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL V-set_CD47 PF08204.11 KFP10090.1 - 0.0013 18.7 1.9 0.0024 17.9 0.1 2.1 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Syndecan PF01034.20 KFP10090.1 - 0.0014 18.5 0.8 0.0085 16.0 0.0 2.7 3 0 0 3 3 2 1 Syndecan domain TMEM154 PF15102.6 KFP10090.1 - 0.0024 17.8 0.9 0.0059 16.5 0.1 1.9 1 1 1 2 2 2 1 TMEM154 protein family Izumo-Ig PF16706.5 KFP10090.1 - 0.006 16.6 0.0 4.2 7.5 0.0 2.7 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain YibE_F PF07907.11 KFP10090.1 - 0.024 14.2 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 YibE/F-like protein DUF5385 PF17359.2 KFP10090.1 - 0.027 14.0 0.2 0.042 13.4 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) UPF0239 PF06783.11 KFP10090.1 - 0.031 14.5 0.5 0.063 13.5 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) EphA2_TM PF14575.6 KFP10090.1 - 0.031 15.2 0.0 0.068 14.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mucin15 PF15672.5 KFP10090.1 - 0.038 13.5 0.4 0.038 13.5 0.4 2.6 2 1 1 3 3 3 0 Cell-membrane associated Mucin15 Vpu PF00558.19 KFP10090.1 - 0.068 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Vpu protein DUF3169 PF11368.8 KFP10090.1 - 0.077 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4834 PF16118.5 KFP10090.1 - 0.097 13.7 0.2 0.24 12.4 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DUF2681 PF10883.8 KFP10090.1 - 0.11 12.9 0.5 0.11 12.9 0.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) FeoB_associated PF12669.7 KFP10090.1 - 0.41 11.1 2.9 0.98 9.9 2.9 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein C2 PF00168.30 KFP10091.1 - 3.2e-36 123.7 0.6 1.9e-19 69.8 0.1 2.2 2 0 0 2 2 2 2 C2 domain Ras PF00071.22 KFP10092.1 - 3.7e-29 101.4 0.1 4.4e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10092.1 - 8.9e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase CENP-M PF11111.8 KFP10092.1 - 0.015 14.5 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) VGCC_beta4Aa_N PF12052.8 KFP10092.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Prefoldin PF02996.17 KFP10093.1 - 5.1e-37 126.4 0.2 7.8e-37 125.8 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFP10093.1 - 0.00038 20.4 4.2 0.063 13.2 0.0 2.3 2 1 0 2 2 2 2 Prefoldin subunit ATG19_autophagy PF12744.7 KFP10093.1 - 0.057 12.6 1.2 0.086 12.0 1.2 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding DUF1664 PF07889.12 KFP10093.1 - 0.4 10.7 2.3 5.5 7.1 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ANTH PF07651.16 KFP10094.1 - 3.5e-69 232.9 1.3 5.8e-69 232.2 1.3 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFP10094.1 - 8.4e-07 29.1 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 ENTH domain STN1_2 PF09170.10 KFP10094.1 - 0.47 10.6 1.6 0.82 9.9 1.6 1.3 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 PH PF00169.29 KFP10095.1 - 6e-20 71.7 0.5 1.2e-19 70.8 0.5 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP10095.1 - 5.7e-05 23.5 4.2 0.00051 20.4 4.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFP10095.1 - 0.049 14.0 0.5 0.12 12.7 0.5 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KFP10095.1 - 0.12 12.4 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.6 KFP10095.1 - 0.59 10.3 2.6 4.5 7.4 2.6 2.1 1 1 0 1 1 1 0 PH domain SNF2_N PF00176.23 KFP10096.1 - 4.4e-80 269.0 0.4 1e-79 267.8 0.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFP10096.1 - 2.2e-42 143.7 3.6 2.2e-42 143.7 3.6 2.7 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 KFP10096.1 - 3e-30 105.2 2.4 3e-30 105.2 2.4 3.5 3 0 0 3 3 2 1 HAND Helicase_C PF00271.31 KFP10096.1 - 9.9e-22 77.4 0.0 1.2e-20 74.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP10096.1 - 8.4e-12 45.4 0.1 9.6e-11 42.0 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP10096.1 - 4.4e-07 29.8 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.6 KFP10096.1 - 2.1e-05 24.9 0.2 2.1e-05 24.9 0.2 5.2 5 0 0 5 5 5 1 DNA-binding domain HDA2-3 PF11496.8 KFP10096.1 - 2.3e-05 23.7 0.0 6.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 KFP10096.1 - 2.9e-05 24.1 0.1 0.44 10.8 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain ERCC3_RAD25_C PF16203.5 KFP10096.1 - 0.0021 17.3 0.0 0.0069 15.6 0.0 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1086 PF06461.11 KFP10096.1 - 0.0044 16.9 0.1 0.041 13.7 0.1 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) UBA_2 PF08587.11 KFP10096.1 - 0.15 12.2 1.7 0.8 9.9 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Tox-GHH PF15636.6 KFP10097.1 - 2.2e-29 101.2 0.9 4.4e-29 100.3 0.9 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ten_N PF06484.12 KFP10097.1 - 1.8e-23 84.1 8.8 2.7e-23 83.5 8.8 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region EGF_2 PF07974.13 KFP10097.1 - 4.8e-19 68.4 151.5 0.00037 20.8 9.4 9.7 8 1 1 9 9 9 7 EGF-like domain RHS_repeat PF05593.14 KFP10097.1 - 2.1e-11 44.1 31.6 0.00052 20.5 1.4 8.7 8 1 1 9 9 9 4 RHS Repeat NHL PF01436.21 KFP10097.1 - 6.6e-07 29.1 1.5 0.13 12.4 0.0 5.8 4 0 0 4 4 4 1 NHL repeat SGL PF08450.12 KFP10097.1 - 0.0012 18.5 0.3 0.49 9.9 0.0 3.7 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region CarboxypepD_reg PF13620.6 KFP10097.1 - 0.011 15.9 0.2 0.037 14.3 0.2 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF1939 PF09154.10 KFP10097.1 - 0.06 13.5 0.2 0.21 11.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) RHS PF03527.14 KFP10097.1 - 0.1 12.4 1.8 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 RHS protein Imm27 PF15590.6 KFP10097.1 - 0.13 12.1 0.5 0.9 9.4 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 27 FliC PF12445.8 KFP10097.1 - 0.16 12.3 1.5 4 7.8 0.5 3.0 1 1 1 2 2 2 0 Flagellin protein SH2 PF00017.24 KFP10098.1 - 2.1e-14 53.4 0.0 2.6e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Cnd3 PF12719.7 KFP10099.1 - 0.0089 15.2 1.1 0.017 14.3 0.4 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain WD40 PF00400.32 KFP10100.1 - 1.3e-08 35.4 2.4 1 10.3 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10100.1 - 0.0012 19.1 0.0 12 6.3 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 KFP10101.1 - 6.3e-18 64.4 1.9 6.3e-18 64.4 1.9 1.5 2 0 0 2 2 2 1 Homeodomain Pou PF00157.17 KFP10101.1 - 1.9e-15 56.6 0.4 5.2e-15 55.2 0.4 1.8 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox_KN PF05920.11 KFP10101.1 - 0.02 14.8 0.1 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4770 PF15994.5 KFP10101.1 - 0.04 14.1 1.1 0.044 14.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) tRNA-synt_1 PF00133.22 KFP10102.1 - 4.3e-40 137.6 0.0 3.4e-25 88.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFP10102.1 - 3.1e-18 65.7 0.1 2.3e-09 36.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFP10102.1 - 3.8e-17 62.6 0.0 1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFP10102.1 - 1.9e-06 27.4 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFP10102.1 - 0.033 13.1 0.5 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) SH3_2 PF07653.17 KFP10103.1 - 1.3e-11 44.0 0.0 2.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP10103.1 - 3.2e-11 42.7 0.0 5.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP10103.1 - 6e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_2 PF13923.6 KFP10103.1 - 8.5e-10 38.3 10.9 1.7e-09 37.4 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP10103.1 - 1.3e-09 37.8 10.3 2.5e-09 36.9 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP10103.1 - 3.6e-09 36.8 9.2 8.4e-09 35.6 9.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP10103.1 - 6.5e-09 35.7 8.5 6.5e-09 35.7 8.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP10103.1 - 1.6e-08 34.2 7.1 3.1e-08 33.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP10103.1 - 1.3e-07 31.4 9.2 2.5e-07 30.5 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KFP10103.1 - 7.9e-06 25.6 7.9 1.6e-05 24.6 7.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFP10103.1 - 0.00015 21.8 9.6 0.00035 20.7 9.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFP10103.1 - 0.0015 18.3 9.3 0.0078 16.1 9.6 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP10103.1 - 0.025 14.8 6.5 0.053 13.8 6.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 KFP10103.1 - 0.21 11.7 4.8 0.5 10.5 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KFP10103.1 - 0.25 11.1 8.0 0.07 12.9 3.0 2.4 1 1 1 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 KFP10103.1 - 1 9.2 8.1 2.5 8.0 7.2 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFP10103.1 - 1.4 8.7 8.0 3 7.7 8.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 KFP10103.1 - 2.1 8.4 5.5 5.4 7.1 5.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KFP10103.1 - 3 7.9 9.7 8 6.6 9.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFP10103.1 - 3.4 7.7 9.3 6.4 6.8 9.3 1.4 1 0 0 1 1 1 0 zinc-ribbons PRELI PF04707.14 KFP10104.1 - 2.3e-38 131.5 0.2 2.8e-38 131.2 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family BTB_2 PF02214.22 KFP10105.1 - 4.7e-16 58.9 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP10105.1 - 0.005 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Dynein_C PF18199.1 KFP10105.1 - 0.0054 16.0 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Yip1 PF04893.17 KFP10106.1 - 1.9e-10 40.7 16.5 2.6e-10 40.3 16.5 1.3 1 0 0 1 1 1 1 Yip1 domain GCR PF02155.15 KFP10107.1 - 4.1e-182 605.3 2.6 5.2e-182 604.9 2.6 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.30 KFP10107.1 - 2.3e-29 102.4 4.9 2.3e-29 102.4 4.9 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP10107.1 - 2.9e-28 98.1 13.0 5.6e-28 97.2 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) BAR_3 PF16746.5 KFP10108.1 - 1.3e-65 221.5 10.2 2.4e-65 220.6 10.2 1.5 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 KFP10108.1 - 7.2e-41 139.5 1.3 2e-40 138.1 0.6 2.0 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 KFP10108.1 - 1.1e-08 34.8 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP10108.1 - 1.4e-06 27.8 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFP10108.1 - 0.00016 22.2 0.0 0.00095 19.6 0.0 2.4 2 0 0 2 2 2 1 PH domain IMD PF08397.11 KFP10108.1 - 0.00028 20.3 2.4 0.00089 18.7 2.4 1.9 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_2 PF07653.17 KFP10108.1 - 0.0016 18.1 0.0 0.0045 16.6 0.0 1.9 1 1 0 1 1 1 1 Variant SH3 domain Sld5 PF05916.11 KFP10108.1 - 3.9 8.0 6.0 5.5 7.5 0.7 3.0 2 1 1 3 3 3 0 GINS complex protein FGF PF00167.18 KFP10110.1 - 1.9e-41 141.1 0.0 2.3e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP10110.1 - 0.00074 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Fascin domain DUF2370 PF10176.9 KFP10112.1 - 1.2e-10 41.5 3.2 7.3e-08 32.3 0.1 2.5 1 1 1 3 3 3 2 Protein of unknown function (DUF2370) Comm PF15957.5 KFP10112.1 - 0.015 15.7 0.2 0.027 14.8 0.2 1.4 1 0 0 1 1 1 0 Commissureless Herpes_UL56 PF04534.12 KFP10112.1 - 0.21 11.0 1.1 0.31 10.5 1.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein WBP-1 PF11669.8 KFP10112.1 - 0.41 11.3 0.1 0.41 11.3 0.1 2.7 3 1 1 4 4 4 0 WW domain-binding protein 1 Glucosamine_iso PF01182.20 KFP10113.1 - 2.2e-13 50.6 0.0 3.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RWD PF05773.22 KFP10114.1 - 4.2e-25 88.3 0.0 9.7e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KFP10114.1 - 5.1e-18 65.1 20.4 2.2e-14 53.4 2.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KFP10114.1 - 0.00081 19.3 17.0 0.00081 19.3 17.0 4.3 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP10114.1 - 0.015 15.6 13.7 0.015 15.6 13.7 4.6 3 1 1 4 4 4 0 Ring finger domain TBPIP PF07106.13 KFP10114.1 - 0.13 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain zf-RING_11 PF17123.5 KFP10114.1 - 2.3 8.0 12.9 8.2 6.3 11.5 2.9 2 0 0 2 2 2 0 RING-like zinc finger HSP70 PF00012.20 KFP10115.1 - 9.1e-193 641.7 17.8 5.5e-187 622.6 0.7 3.0 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFP10115.1 - 2.3e-10 39.8 0.0 4.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Clr5 PF14420.6 KFP10115.1 - 0.051 13.8 0.1 0.051 13.8 0.1 3.2 4 0 0 4 4 4 0 Clr5 domain Raco_middle PF17651.1 KFP10115.1 - 0.051 13.2 0.1 6.7 6.4 0.1 2.6 2 0 0 2 2 2 0 RACo middle region F-box-like_2 PF13013.6 KFP10115.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain DUF853 PF05872.12 KFP10115.1 - 3.3 6.2 12.6 0.4 9.2 1.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DDHD PF02862.17 KFP10115.1 - 5 7.2 12.1 0.13 12.4 3.5 2.2 2 0 0 2 2 2 0 DDHD domain Connexin PF00029.19 KFP10115.1 - 7.2 6.3 6.0 24 4.6 6.0 1.9 1 0 0 1 1 1 0 Connexin zf-CCHC_3 PF13917.6 KFP10116.1 - 1.2e-18 66.8 4.3 2.5e-18 65.7 4.3 1.6 1 0 0 1 1 1 1 Zinc knuckle CLIP1_ZNF PF16641.5 KFP10116.1 - 0.061 13.2 1.6 0.092 12.7 1.6 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle PNISR PF15996.5 KFP10116.1 - 0.53 10.5 24.5 0.67 10.2 24.5 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR V_ATPase_I PF01496.19 KFP10116.1 - 2.6 5.8 5.5 2.7 5.8 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Menin PF05053.13 KFP10116.1 - 3.5 5.9 17.2 4.3 5.6 17.2 1.1 1 0 0 1 1 1 0 Menin WDCP PF15390.6 KFP10116.1 - 4 5.7 13.3 4.5 5.5 13.3 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4746 PF15928.5 KFP10116.1 - 4.3 6.7 7.2 5.1 6.4 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 KFP10116.1 - 6.7 4.8 25.5 7.6 4.6 25.5 1.0 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.13 KFP10117.1 - 0 1409.7 141.2 0 1409.5 141.2 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Peptidase_S64 PF08192.11 KFP10117.1 - 0.0017 16.9 18.9 0.0017 16.9 18.9 4.8 3 2 1 4 4 4 1 Peptidase family S64 LEAP-2 PF07359.11 KFP10118.1 - 1.5e-42 143.3 6.7 1.6e-42 143.2 6.7 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.18 KFP10118.1 - 0.002 18.4 0.5 0.002 18.4 0.5 1.2 1 0 0 1 1 1 1 EB module ASD1 PF08688.10 KFP10119.1 - 1.5e-37 129.7 8.6 1.5e-37 129.7 8.6 1.7 2 0 0 2 2 2 1 Apx/Shroom domain ASD1 ASD2 PF08687.11 KFP10120.1 - 8.9e-71 238.8 15.0 1e-70 238.6 15.0 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Sod_Ni PF09055.11 KFP10120.1 - 0.0015 19.1 0.7 0.011 16.3 0.3 2.0 1 1 1 2 2 2 1 Nickel-containing superoxide dismutase DASH_Spc34 PF08657.10 KFP10120.1 - 0.0024 17.7 1.7 0.0032 17.3 1.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 GlgS PF08971.11 KFP10120.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein CorA PF01544.18 KFP10120.1 - 0.066 12.5 3.4 0.059 12.7 0.8 1.8 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Gastrin PF00918.17 KFP10120.1 - 0.066 14.2 0.4 0.095 13.7 0.4 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF5320 PF17253.2 KFP10120.1 - 0.079 14.0 2.9 3.9 8.6 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF2721 PF11026.8 KFP10120.1 - 0.16 11.8 0.4 0.38 10.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) PCRF PF03462.18 KFP10120.1 - 1.3 8.8 6.5 1.1 9.1 4.0 1.8 2 0 0 2 2 2 0 PCRF domain Syntaxin-6_N PF09177.11 KFP10120.1 - 3.3 8.3 7.2 12 6.5 0.6 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Septin PF00735.18 KFP10121.1 - 3.3e-96 321.9 2.3 3.3e-96 321.9 2.3 2.1 2 1 1 3 3 3 1 Septin MMR_HSR1 PF01926.23 KFP10121.1 - 2e-06 27.9 0.8 4.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP10121.1 - 0.00018 21.1 6.2 1.3 8.6 1.0 3.3 3 0 0 3 3 3 3 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP10121.1 - 0.00027 21.4 0.1 0.00097 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFP10121.1 - 0.00046 20.1 7.0 0.0041 17.0 0.0 3.5 3 2 0 3 3 3 1 RsgA GTPase Roc PF08477.13 KFP10121.1 - 0.00049 20.3 0.1 0.0018 18.5 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFP10121.1 - 0.0008 19.7 1.9 0.0013 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 KFP10121.1 - 0.0067 16.0 0.7 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_7 PF12775.7 KFP10121.1 - 0.0071 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Microtub_bd PF16796.5 KFP10121.1 - 0.024 14.6 5.3 0.09 12.7 0.0 2.8 2 0 0 2 2 2 0 Microtubule binding ABC_tran PF00005.27 KFP10121.1 - 0.026 15.1 0.1 0.026 15.1 0.1 2.5 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KFP10121.1 - 0.032 14.6 0.0 0.098 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IMD PF08397.11 KFP10121.1 - 0.057 12.8 13.5 0.11 11.9 13.5 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_24 PF13479.6 KFP10121.1 - 0.1 12.3 1.2 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFP10121.1 - 0.1 13.1 18.1 0.43 11.0 0.4 2.5 2 1 0 2 2 2 0 AAA domain Atg14 PF10186.9 KFP10121.1 - 0.11 11.6 13.4 0.3 10.1 13.4 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_29 PF13555.6 KFP10121.1 - 0.16 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fzo_mitofusin PF04799.13 KFP10121.1 - 0.89 9.1 10.1 0.65 9.5 8.0 1.9 2 0 0 2 2 2 0 fzo-like conserved region DUF87 PF01935.17 KFP10121.1 - 0.91 9.6 0.0 0.91 9.6 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 KFP10121.1 - 3.8 7.0 11.9 7.3 6.1 11.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KFP10121.1 - 6.4 6.5 8.2 23 4.7 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Kinesin PF00225.23 KFP10122.1 - 4.9e-122 407.0 0.1 1.3e-121 405.7 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP10122.1 - 5.7e-27 94.5 0.1 3.7e-26 91.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding CheZ PF04344.13 KFP10122.1 - 0.0038 17.2 6.3 0.0038 17.2 6.3 2.7 3 0 0 3 3 3 1 Chemotaxis phosphatase, CheZ AAA_22 PF13401.6 KFP10122.1 - 0.36 11.1 8.5 1.9 8.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain IL4 PF00727.18 KFP10123.1 - 3.3e-10 40.2 0.3 3.9e-10 39.9 0.3 1.1 1 0 0 1 1 1 1 Interleukin 4 AAA_15 PF13175.6 KFP10124.1 - 1.1e-12 48.4 21.8 1.1e-10 41.7 0.3 5.7 1 1 4 5 5 3 2 AAA ATPase domain Rad50_zn_hook PF04423.14 KFP10124.1 - 1.3e-12 47.3 0.1 1.3e-12 47.3 0.1 5.7 5 0 0 5 5 4 1 Rad50 zinc hook motif AAA_21 PF13304.6 KFP10124.1 - 1.1e-09 38.6 14.2 8.4e-06 25.8 0.0 4.2 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFP10124.1 - 5.1e-09 36.9 182.0 9.6e+03 -3.1 5.4 9.8 2 1 1 3 3 2 0 AAA domain SbcCD_C PF13558.6 KFP10124.1 - 9.3e-07 29.0 0.1 4.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KFP10124.1 - 3.2e-06 26.7 36.7 1.9e-05 24.2 0.1 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFP10124.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2703 PF10865.8 KFP10124.1 - 0.011 15.9 0.5 0.011 15.9 0.5 6.1 6 1 1 7 7 7 0 Domain of unknown function (DUF2703) NPV_P10 PF05531.12 KFP10124.1 - 0.015 15.7 2.0 0.015 15.7 2.0 10.2 6 3 5 11 11 11 0 Nucleopolyhedrovirus P10 protein AAA_16 PF13191.6 KFP10124.1 - 0.48 10.8 0.0 0.48 10.8 0.0 4.7 5 2 0 5 5 5 0 AAA ATPase domain GxGYxYP_C PF14323.6 KFP10124.1 - 9.9 6.0 8.0 0.54 10.1 1.3 2.3 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain IL5 PF02025.15 KFP10125.1 - 2.7e-08 34.1 0.2 3.4e-08 33.7 0.2 1.1 1 0 0 1 1 1 1 Interleukin 5 RIH_assoc PF08454.11 KFP10125.1 - 4.8e-05 23.2 0.4 6.3e-05 22.8 0.4 1.3 1 1 0 1 1 1 1 RyR and IP3R Homology associated DUF1882 PF08966.11 KFP10125.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) IRF PF00605.17 KFP10126.1 - 3e-40 136.7 0.6 5.3e-40 136.0 0.6 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Sugar_tr PF00083.24 KFP10127.1 - 5.5e-27 94.7 19.7 8.2e-27 94.2 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP10127.1 - 1.9e-21 76.4 59.9 4.8e-19 68.5 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP10128.1 - 7.8e-27 94.2 18.7 1.2e-26 93.6 18.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP10128.1 - 3.7e-23 82.0 52.7 2.9e-21 75.8 32.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP10128.1 - 0.0005 18.7 4.0 0.0005 18.7 4.0 4.0 2 2 1 4 4 4 1 MFS/sugar transport protein DUF4749 PF15936.5 KFP10129.1 - 1.4e-20 74.2 0.1 2.6e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) LIM PF00412.22 KFP10129.1 - 8.5e-15 54.7 3.7 1.7e-14 53.8 3.7 1.4 1 0 0 1 1 1 1 LIM domain PDZ PF00595.24 KFP10129.1 - 6.4e-11 42.5 0.1 1.3e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP10129.1 - 2.8e-07 30.3 0.0 5.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP10129.1 - 0.0027 18.0 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain zf-SNAP50_C PF12251.8 KFP10129.1 - 0.26 10.9 2.2 1.4 8.6 0.8 2.2 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal P4Ha_N PF08336.11 KFP10130.1 - 8.2e-40 135.9 0.3 8.2e-40 135.9 0.3 2.1 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFP10130.1 - 6.8e-16 58.9 0.1 1.9e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP10130.1 - 6.6e-06 26.5 0.0 1.6e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KFP10132.1 - 5.5e-109 364.6 0.0 7.6e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP10132.1 - 5.9e-05 24.0 0.0 0.00016 22.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myf5 PF12232.8 KFP10133.1 - 0.29 12.0 6.6 1.7 9.4 1.1 2.6 2 0 0 2 2 2 0 Myogenic determination factor 5 FNIP_M PF14637.6 KFP10134.1 - 4.8e-89 298.2 0.0 8.7e-89 297.4 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFP10134.1 - 7.4e-73 244.2 0.1 1.8e-72 243.0 0.1 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFP10134.1 - 1.7e-25 90.8 12.0 3.8e-25 89.7 2.3 3.8 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus Serpin PF00079.20 KFP10135.1 - 1.6e-114 383.1 2.2 1.8e-114 383.0 2.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.14 KFP10135.1 - 0.044 13.4 0.5 0.075 12.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF1241 PF06840.11 KFP10137.1 - 2.1e-63 212.4 3.2 2.9e-63 212.0 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) FH2 PF02181.23 KFP10137.1 - 0.00077 18.7 2.1 0.00077 18.7 2.1 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain CENP-L PF13092.6 KFP10137.1 - 0.0072 16.5 0.1 0.0088 16.3 0.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 CREPT PF16566.5 KFP10137.1 - 0.018 15.2 0.8 0.032 14.4 0.8 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Med11 PF10280.9 KFP10137.1 - 0.028 14.9 1.1 0.077 13.5 0.4 2.0 1 1 2 3 3 3 0 Mediator complex protein SabA_adhesion PF18304.1 KFP10137.1 - 0.038 13.2 0.6 0.053 12.7 0.6 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain DUF5344 PF17279.2 KFP10137.1 - 0.056 14.0 1.5 0.23 12.0 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF4208 PF13907.6 KFP10137.1 - 0.059 13.8 1.1 20 5.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) SesA PF17107.5 KFP10137.1 - 0.077 13.2 2.4 0.1 12.8 0.9 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases GCN5L1 PF06320.13 KFP10137.1 - 0.083 13.0 2.0 0.42 10.8 0.8 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Syntaxin_2 PF14523.6 KFP10137.1 - 0.11 12.9 5.7 0.39 11.1 5.7 1.9 1 1 0 1 1 1 0 Syntaxin-like protein Sec23_trunk PF04811.15 KFP10137.1 - 0.12 11.9 1.9 1.5 8.3 0.3 2.6 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain TFIIF_beta PF02270.15 KFP10137.1 - 0.12 12.5 0.9 0.39 10.9 0.2 2.2 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain NAAA-beta PF15508.6 KFP10137.1 - 0.19 12.0 0.7 2.8 8.3 0.1 2.7 3 0 0 3 3 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4850 PF16142.5 KFP10139.1 - 0.04 13.4 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4850) AChE_tetra PF08674.10 KFP10140.1 - 5.4e-23 80.4 7.9 1.1e-22 79.5 7.9 1.5 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain COesterase PF00135.28 KFP10140.1 - 0.013 14.4 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DLP_helical PF18709.1 KFP10140.1 - 0.069 12.3 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Kinesin PF00225.23 KFP10141.1 - 1.2e-102 343.3 0.8 4.1e-102 341.5 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 KFP10141.1 - 1e-45 154.2 0.0 2.5e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 KFP10141.1 - 1.8e-14 53.9 0.0 4.4e-11 42.9 0.0 3.2 3 0 0 3 3 3 2 Microtubule binding ADIP PF11559.8 KFP10141.1 - 0.0018 18.4 11.1 0.0018 18.4 11.1 2.1 2 0 0 2 2 1 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFP10141.1 - 0.002 18.1 18.0 0.002 18.1 18.0 2.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.10 KFP10141.1 - 0.092 13.1 4.9 0.61 10.5 0.1 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sec8_exocyst PF04048.14 KFP10141.1 - 0.097 12.6 6.5 0.12 12.2 4.1 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain SpecificRecomb PF10136.9 KFP10141.1 - 0.13 10.5 1.8 0.2 9.9 1.8 1.1 1 0 0 1 1 1 0 Site-specific recombinase GBP_C PF02841.14 KFP10141.1 - 0.28 10.6 15.9 0.59 9.5 15.9 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ERM PF00769.19 KFP10141.1 - 0.52 10.1 19.5 0.024 14.4 12.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FlxA PF14282.6 KFP10141.1 - 0.68 10.0 9.3 2.2 8.3 9.3 1.8 1 0 0 1 1 1 0 FlxA-like protein DUF16 PF01519.16 KFP10141.1 - 0.8 10.2 11.8 0.2 12.1 7.2 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 KFP10141.1 - 1.1 7.1 11.5 1.7 6.5 11.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MBR1 PF17058.5 KFP10141.1 - 1.1 9.5 8.5 5.4 7.3 1.0 3.1 3 0 0 3 3 3 0 Mitochondrial biogenesis regulation protein 1 DUF3847 PF12958.7 KFP10141.1 - 2.1 8.5 14.0 9.2 6.5 5.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) FapA PF03961.13 KFP10141.1 - 3 6.3 11.4 5 5.6 11.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 KFP10141.1 - 4.3 7.6 6.5 3.8 7.8 4.2 2.1 1 1 1 2 2 2 0 Haemolysin XhlA HlyIII PF03006.20 KFP10142.1 - 5.3e-41 140.8 17.6 5.3e-41 140.8 17.6 1.3 2 0 0 2 2 2 1 Haemolysin-III related LRR_9 PF14580.6 KFP10143.1 - 2.2e-19 69.6 0.2 2.7e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP10143.1 - 2.8e-13 49.8 13.3 7.1e-10 39.0 2.0 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP10143.1 - 1.4e-08 34.4 9.3 6.2e-07 29.1 5.1 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFP10143.1 - 2.4e-07 30.3 9.9 0.0025 17.8 0.6 3.9 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFP10143.1 - 5.6e-05 23.1 6.9 0.78 10.5 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat SDA1 PF05285.12 KFP10143.1 - 0.08 12.4 18.7 0.087 12.2 18.7 1.1 1 0 0 1 1 1 0 SDA1 LRR_2 PF07723.13 KFP10143.1 - 0.21 12.3 4.4 11 6.9 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat Mpp10 PF04006.12 KFP10143.1 - 0.97 7.8 21.6 1.1 7.6 21.6 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 KFP10143.1 - 1.1 8.6 17.4 1.3 8.3 17.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.11 KFP10143.1 - 1.8 8.1 17.3 2.8 7.5 17.3 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KFP10143.1 - 5.8 5.0 23.0 6.6 4.8 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family DASH_Dam1 PF08653.10 KFP10145.1 - 0.079 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 Ribosomal_L29 PF00831.23 KFP10146.1 - 0.00054 19.9 0.7 0.00054 19.9 0.7 2.6 2 1 1 3 3 3 1 Ribosomal L29 protein XFP_N PF09364.10 KFP10146.1 - 0.042 12.7 0.0 0.043 12.6 0.0 1.0 1 0 0 1 1 1 0 XFP N-terminal domain SCAI PF12070.8 KFP10147.1 - 1.5e-212 707.3 8.8 4e-212 705.8 8.8 1.6 1 1 0 1 1 1 1 Protein SCAI GRIP PF01465.20 KFP10148.1 - 1.2e-14 53.9 1.8 2.5e-14 52.9 0.5 2.4 2 0 0 2 2 2 1 GRIP domain ABC_tran_CTD PF16326.5 KFP10148.1 - 0.016 15.4 7.7 0.016 15.4 7.7 11.0 2 2 10 12 12 12 0 ABC transporter C-terminal domain Nuc_N PF14448.6 KFP10148.1 - 0.51 10.2 6.1 3.7 7.5 0.1 3.3 3 0 0 3 3 3 0 Nuclease N terminal Spc7 PF08317.11 KFP10148.1 - 1 8.2 145.2 0.66 8.8 28.0 6.2 1 1 5 6 6 6 0 Spc7 kinetochore protein Metallophos PF00149.28 KFP10149.1 - 3.6e-28 99.5 0.1 4.5e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_3 PF13415.6 KFP10150.1 - 1.3e-24 85.9 4.9 1e-06 28.8 0.1 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP10150.1 - 8.5e-21 73.7 6.2 1.8e-07 31.0 0.0 5.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFP10150.1 - 2.2e-20 72.0 0.1 6.3e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KFP10150.1 - 5.6e-20 70.9 2.3 1.3e-06 28.4 0.1 4.0 2 1 2 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KFP10150.1 - 6.3e-20 70.7 4.5 2.1e-05 24.4 0.1 4.8 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 KFP10150.1 - 6.1e-13 48.2 4.2 2.4e-05 24.1 0.0 4.1 4 1 0 4 4 4 3 Kelch motif HSP70 PF00012.20 KFP10151.1 - 3e-262 871.2 10.2 3.4e-262 871.0 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFP10151.1 - 3.5e-17 62.2 0.1 8e-17 61.0 0.1 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KFP10151.1 - 0.004 16.5 0.2 0.013 14.8 0.1 1.9 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 KFP10151.1 - 0.0071 15.4 0.8 0.02 13.9 0.5 1.7 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KFP10151.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RasGAP PF00616.19 KFP10152.1 - 3.9e-35 121.5 0.1 1.2e-34 119.9 0.1 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 KFP10152.1 - 1.2e-28 99.3 0.0 3.9e-28 97.7 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFP10152.1 - 3.1e-12 46.6 0.2 1.1e-11 44.8 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) EF-hand_14 PF17959.1 KFP10152.1 - 0.13 12.6 0.1 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain SURF2 PF05477.11 KFP10152.1 - 0.3 10.7 6.0 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) CRIM PF16978.5 KFP10153.1 - 2.7e-36 124.8 0.0 5.7e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1 PF05422.12 KFP10153.1 - 3.6e-33 115.1 12.0 3.1e-30 105.6 7.5 3.6 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) SIN1_PH PF16979.5 KFP10153.1 - 2.3e-28 98.6 0.3 4.4e-28 97.8 0.3 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology E3_UbLigase_RBR PF18091.1 KFP10153.1 - 0.12 12.5 0.4 0.77 9.9 0.0 2.4 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain PBC PF03792.13 KFP10154.1 - 3.8e-48 163.8 0.0 8.5e-48 162.6 0.0 1.5 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFP10154.1 - 2.3e-19 69.0 1.2 4.4e-19 68.1 1.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP10154.1 - 1.9e-15 56.4 0.0 4.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFP10154.1 - 0.016 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Auxin_canalis PF05703.11 KFP10154.1 - 0.044 13.7 4.4 0.085 12.8 4.4 1.5 1 1 0 1 1 1 0 Auxin canalisation DUF2464 PF10240.9 KFP10155.1 - 1.4e-65 221.4 0.0 1.6e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Multivesicular body subunit 12 Homeodomain PF00046.29 KFP10156.1 - 2.5e-18 65.6 2.5 5.9e-18 64.5 2.5 1.7 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KFP10156.1 - 3.9e-17 62.2 11.3 6.4e-17 61.5 11.3 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 KFP10156.1 - 8.2e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain BTB PF00651.31 KFP10157.1 - 9.1e-27 93.5 0.0 1.6e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP10157.1 - 3.5e-09 36.7 16.1 1.7e-06 28.1 0.5 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP10157.1 - 6.9e-07 29.4 23.9 0.0015 18.8 2.5 4.4 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP10157.1 - 0.00012 22.6 21.4 0.031 15.1 1.8 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFP10157.1 - 0.0032 17.4 2.9 0.0032 17.4 2.9 2.1 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-met PF12874.7 KFP10157.1 - 0.14 12.6 10.8 11 6.5 0.7 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP10157.1 - 0.33 11.3 8.2 0.79 10.1 4.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc ribbon DUF2256 PF10013.9 KFP10157.1 - 2.3 8.4 7.6 1.6 8.9 0.7 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 KFP10157.1 - 3.1 8.0 6.5 8.7 6.6 0.3 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFP10157.1 - 4 7.6 18.4 0.71 9.9 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_Tnp_IS91 PF14319.6 KFP10157.1 - 4 7.5 7.9 0.47 10.5 1.6 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain RasGEF PF00617.19 KFP10158.1 - 4e-51 173.7 3.6 1.5e-50 171.8 0.7 2.1 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 KFP10158.1 - 1.8e-10 41.3 0.0 3.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Fibrinogen_C PF00147.18 KFP10159.1 - 2.6e-74 249.8 12.1 3.6e-74 249.3 12.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fer4_NifH PF00142.18 KFP10159.1 - 0.015 14.7 1.1 0.044 13.2 1.4 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SLATT_5 PF18160.1 KFP10159.1 - 0.39 10.0 3.4 0.94 8.8 3.4 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF16 PF01519.16 KFP10159.1 - 1.5 9.4 11.9 0.97 10.0 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 WD40 PF00400.32 KFP10160.1 - 4.7e-16 58.9 11.3 1.4e-05 25.7 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 KFP10160.1 - 5.1e-08 32.7 4.7 1.7e-07 31.0 3.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFP10160.1 - 1.9e-05 24.4 1.3 7.5e-05 22.5 0.6 2.3 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KFP10160.1 - 0.002 18.4 1.1 5.1 7.5 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KFP10161.1 - 1.2e-67 228.5 0.2 2.2e-67 227.6 0.2 1.5 1 0 0 1 1 1 1 CNH domain Rap_GAP PF02145.15 KFP10161.1 - 2.1e-67 226.3 0.1 4.2e-67 225.3 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP CAP_GLY PF01302.25 KFP10162.1 - 4.4e-25 87.5 2.0 5.5e-25 87.2 2.0 1.1 1 0 0 1 1 1 1 CAP-Gly domain CENP-F_leu_zip PF10473.9 KFP10163.1 - 0.0029 17.6 21.7 0.012 15.7 21.7 1.8 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KFP10163.1 - 0.012 15.7 16.1 0.35 11.0 4.5 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation ADIP PF11559.8 KFP10163.1 - 0.021 14.9 16.0 0.028 14.5 16.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3972 PF13118.6 KFP10163.1 - 0.022 15.2 2.2 0.022 15.2 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Gemin7 PF11095.8 KFP10163.1 - 0.029 14.2 0.0 0.054 13.4 0.0 1.5 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) CCDC-167 PF15188.6 KFP10163.1 - 0.034 14.5 20.2 0.073 13.4 3.5 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Fez1 PF06818.15 KFP10163.1 - 0.056 13.9 15.9 0.071 13.6 15.9 1.1 1 0 0 1 1 1 0 Fez1 Atg14 PF10186.9 KFP10163.1 - 0.072 12.2 12.7 0.08 12.0 12.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MbeD_MobD PF04899.12 KFP10163.1 - 0.074 13.2 8.3 1.2 9.3 0.1 3.0 2 1 1 3 3 3 0 MbeD/MobD like LPP PF04728.13 KFP10163.1 - 0.085 13.3 7.7 1.4 9.4 0.2 2.8 2 2 1 3 3 2 0 Lipoprotein leucine-zipper bZIP_1 PF00170.21 KFP10163.1 - 0.12 12.5 18.6 0.28 11.3 2.7 3.3 2 2 1 3 3 3 0 bZIP transcription factor HOOK PF05622.12 KFP10163.1 - 0.15 10.1 18.5 0.16 10.1 18.5 1.0 1 0 0 1 1 1 0 HOOK protein DUF5082 PF16888.5 KFP10163.1 - 0.16 12.2 12.3 1.2 9.4 6.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Phage_GP20 PF06810.11 KFP10163.1 - 0.25 11.2 15.4 0.03 14.1 5.9 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 CLZ PF16526.5 KFP10163.1 - 0.64 10.4 19.0 0.081 13.3 3.8 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 KFP10163.1 - 0.65 8.8 19.1 2.9 6.7 19.0 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 KFP10163.1 - 0.73 8.6 19.9 0.89 8.4 19.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pepsin-I3 PF06394.13 KFP10163.1 - 0.79 10.0 6.9 0.24 11.6 2.9 2.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain FlxA PF14282.6 KFP10163.1 - 0.88 9.6 14.9 3.6 7.6 9.0 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF2730 PF10805.8 KFP10163.1 - 0.97 9.6 11.0 0.16 12.1 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TMPIT PF07851.13 KFP10163.1 - 1.1 8.4 11.7 1.4 8.1 11.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Nup54 PF13874.6 KFP10163.1 - 1.2 9.2 12.9 1.1 9.3 6.4 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin_2 PF01920.20 KFP10163.1 - 1.3 9.0 21.1 0.058 13.4 2.9 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF641 PF04859.12 KFP10163.1 - 1.5 9.1 14.8 1.9 8.8 6.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PRKG1_interact PF15898.5 KFP10163.1 - 1.6 9.7 17.8 4.5e+02 1.8 17.8 2.3 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 KFP10163.1 - 2.5 8.6 22.4 1.5e+03 -0.3 22.4 2.7 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KFP10163.1 - 2.6 8.2 19.3 1.1 9.4 2.1 3.3 3 0 0 3 3 3 0 Basic region leucine zipper Ax_dynein_light PF10211.9 KFP10163.1 - 2.6 8.0 19.7 0.14 12.1 7.9 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 KFP10163.1 - 2.9 7.2 11.4 3.2 7.0 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 KFP10163.1 - 3.9 6.8 18.1 1 8.7 4.4 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF724 PF05266.14 KFP10163.1 - 4.2 7.2 16.9 19 5.0 16.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 KFP10163.1 - 5.6 7.7 15.7 4 8.1 1.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 KFP10163.1 - 5.6 7.1 14.1 4.7 7.4 0.1 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain FlaC_arch PF05377.11 KFP10163.1 - 7 7.1 12.9 8.6 6.8 2.5 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KFP10163.1 - 7 7.3 15.6 5.3 7.7 0.4 2.6 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 KFP10163.1 - 8.2 6.5 21.6 13 5.8 12.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KFP10163.1 - 8.6 5.6 20.0 2 7.7 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KFP10163.1 - 9.2 6.8 13.0 1.5 9.4 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Iso_dh PF00180.20 KFP10164.1 - 2.4e-42 145.3 0.2 2.7e-42 145.2 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_3 PF07726.11 KFP10164.1 - 0.049 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps16_N PF04841.13 KFP10165.1 - 6.9e-71 239.1 0.0 8.9e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KFP10165.1 - 2.1e-59 201.1 0.6 2.9e-59 200.7 0.6 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region DZR PF12773.7 KFP10165.1 - 0.63 10.1 4.3 18 5.5 0.7 2.8 2 0 0 2 2 2 0 Double zinc ribbon TLV_coat PF00429.19 KFP10167.1 - 0.00092 18.0 0.2 0.00099 17.9 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) BTB PF00651.31 KFP10168.1 - 1.1e-23 83.5 0.4 4.2e-22 78.5 0.2 2.8 2 1 1 3 3 3 1 BTB/POZ domain Ank_2 PF12796.7 KFP10168.1 - 3.2e-19 69.3 0.0 1.2e-09 38.6 0.0 3.7 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP10168.1 - 1.9e-18 64.6 0.1 1.4e-05 25.1 0.0 4.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFP10168.1 - 2e-16 60.1 0.1 0.00032 21.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP10168.1 - 7.5e-16 57.8 0.3 9.7e-07 29.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP10168.1 - 1.7e-12 47.3 0.5 0.006 16.9 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.15 KFP10168.1 - 0.0013 18.8 0.8 0.0053 16.8 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 KFP10168.1 - 0.13 12.4 0.0 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) WD40 PF00400.32 KFP10170.1 - 4.8e-13 49.4 5.9 0.00069 20.4 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10170.1 - 6.4e-06 26.4 0.2 0.0088 16.3 0.2 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain zf_PR_Knuckle PF18445.1 KFP10171.1 - 1.2e-28 98.7 13.4 8.4e-28 95.9 3.6 4.0 3 0 0 3 3 3 2 PR zinc knuckle motif zf-H2C2_2 PF13465.6 KFP10171.1 - 4.6e-26 90.0 54.9 1.3e-07 31.7 0.7 8.3 8 1 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP10171.1 - 7.8e-20 70.2 63.1 1.3e-05 25.4 1.8 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP10171.1 - 6.3e-17 60.8 64.1 0.00093 19.8 1.6 8.8 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP10171.1 - 0.00011 22.4 51.3 0.027 14.7 0.2 8.1 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP10171.1 - 0.00011 22.5 44.0 0.00085 19.6 1.1 7.5 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP10171.1 - 0.0033 17.2 1.2 0.0033 17.2 1.2 6.3 6 1 0 6 6 6 3 C2H2-type zinc-finger domain Mu-like_Com PF10122.9 KFP10171.1 - 0.097 12.1 5.5 0.075 12.5 2.9 2.2 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-C2H2_2 PF12756.7 KFP10171.1 - 1.3 9.4 36.9 7.7 6.9 10.0 5.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) HLH PF00010.26 KFP10172.1 - 9.5e-18 63.9 2.2 1.4e-17 63.4 2.2 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RtcB PF01139.17 KFP10173.1 - 6.2e-146 486.8 0.6 7e-146 486.6 0.6 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cu-oxidase_4 PF02578.15 KFP10173.1 - 0.045 13.4 0.1 0.22 11.1 0.2 1.9 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase LBP_BPI_CETP_C PF02886.17 KFP10174.1 - 6.2e-40 137.1 0.3 7.7e-40 136.8 0.3 1.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP_C PF02886.17 KFP10175.1 - 1.6e-43 148.9 0.6 3.4e-42 144.5 0.2 2.1 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFP10175.1 - 1.1e-24 86.9 0.3 1.2e-23 83.6 0.0 2.3 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain F-box-like PF12937.7 KFP10176.1 - 4.6e-10 39.2 2.4 1.1e-09 38.1 2.4 1.7 1 0 0 1 1 1 1 F-box-like PI31_Prot_N PF11566.8 KFP10176.1 - 6.5e-06 26.1 0.1 2.5e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 PI31 proteasome regulator N-terminal F-box PF00646.33 KFP10176.1 - 1.8e-05 24.5 1.2 3.9e-05 23.4 1.2 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFP10176.1 - 0.023 15.2 0.7 0.048 14.2 0.7 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Synapsin_C PF02750.14 KFP10177.1 - 1e-101 338.7 0.8 1.2e-101 338.4 0.8 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain RimK PF08443.11 KFP10177.1 - 0.00057 19.5 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TIMP PF00965.17 KFP10179.1 - 5.4e-52 176.2 5.0 6e-52 176.1 5.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Synapsin PF02078.16 KFP10180.1 - 1.1e-44 150.8 0.0 1.8e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Synapsin, N-terminal domain Synapsin_C PF02750.14 KFP10180.1 - 2.4e-23 82.7 0.5 4e-23 82.0 0.5 1.4 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin_N PF10581.9 KFP10180.1 - 9.3e-20 70.3 4.3 2e-19 69.2 4.3 1.6 1 0 0 1 1 1 1 Synapsin N-terminal Glyco_transf_49 PF13896.6 KFP10182.1 - 6.8e-58 196.6 4.0 4.8e-45 154.3 1.5 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 KFP10182.1 - 3.2e-19 69.5 0.7 5.7e-19 68.7 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP10182.1 - 8.4e-07 28.7 3.5 1.4e-06 28.0 3.5 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 WD40_alt PF14077.6 KFP10182.1 - 1.3 8.9 3.1 4.2 7.3 3.1 1.9 1 0 0 1 1 1 0 Alternative WD40 repeat motif Homeodomain PF00046.29 KFP10188.1 - 1.4e-23 82.4 4.4 2.2e-23 81.8 4.4 1.3 1 0 0 1 1 1 1 Homeodomain MRP-L20 PF12824.7 KFP10188.1 - 0.0017 18.6 0.3 0.0021 18.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.11 KFP10188.1 - 0.002 18.0 1.2 0.0025 17.7 0.2 1.7 2 0 0 2 2 2 1 Homeobox KN domain DUF4171 PF13775.6 KFP10189.1 - 6.8e-47 159.3 25.3 6.8e-47 159.3 25.3 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4171) HMG_box PF00505.19 KFP10189.1 - 3.2e-15 56.3 2.4 3.2e-15 56.3 2.4 3.6 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP10189.1 - 6.5e-09 36.3 2.0 6.5e-09 36.3 2.0 2.6 2 0 0 2 2 2 1 HMG-box domain VHS PF00790.19 KFP10190.1 - 4.5e-45 153.0 0.0 8.1e-45 152.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFP10190.1 - 1.9e-24 85.8 4.0 4e-24 84.7 4.0 1.5 1 0 0 1 1 1 1 GAT domain Heme_oxygenase PF01126.20 KFP10191.1 - 3.4e-80 268.7 2.9 4.1e-80 268.4 2.9 1.1 1 0 0 1 1 1 1 Heme oxygenase COX5A PF02284.16 KFP10191.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va MCM PF00493.23 KFP10192.1 - 1.8e-100 334.7 0.0 2.9e-100 334.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP10192.1 - 2.9e-40 137.0 0.7 5.6e-40 136.1 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFP10192.1 - 4.1e-24 84.8 0.5 1.4e-23 83.1 0.2 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KFP10192.1 - 3.3e-18 66.2 1.2 8e-18 64.9 1.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFP10192.1 - 1.1e-06 28.2 0.0 0.00045 19.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFP10192.1 - 0.00047 20.2 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFP10192.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrmB PF01978.19 KFP10192.1 - 0.028 14.3 1.3 0.54 10.2 0.4 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma54_activat PF00158.26 KFP10192.1 - 0.032 13.9 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Ras PF00071.22 KFP10194.1 - 4.4e-40 136.9 0.0 6.8e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10194.1 - 5.4e-14 52.4 0.0 9.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP10194.1 - 5.3e-08 32.5 0.0 7.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP10194.1 - 0.00091 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP10194.1 - 0.0034 17.0 0.0 0.01 15.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP10194.1 - 0.027 13.9 0.0 0.097 12.1 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP10194.1 - 0.036 13.5 0.1 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KFP10194.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KFP10194.1 - 0.17 11.8 0.1 2.4 8.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Globin PF00042.22 KFP10195.1 - 9.1e-23 80.9 0.1 1.5e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 Globin AbiJ_NTD5 PF18865.1 KFP10195.1 - 0.05 13.4 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 TPR_8 PF13181.6 KFP10195.1 - 0.085 13.1 0.1 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fox-1_C PF12414.8 KFP10198.1 - 5.7e-26 90.7 6.6 5.7e-26 90.7 6.6 2.6 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFP10198.1 - 1.4e-18 66.5 0.1 2.2e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP10198.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 KFP10199.1 - 1.8e-28 98.5 0.1 2.2e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP10199.1 - 2e-08 34.6 0.1 3.3e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP10199.1 - 8.8e-06 25.8 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KFP10199.1 - 0.00029 20.8 0.1 0.00041 20.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 KFP10199.1 - 0.00042 20.6 0.0 0.043 14.1 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KFP10199.1 - 0.0031 17.4 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DSBA PF01323.20 KFP10199.1 - 0.0076 16.0 0.0 0.23 11.2 0.0 2.0 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.6 KFP10199.1 - 0.013 15.3 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 KFP10199.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Pyr_redox_3 PF13738.6 KFP10201.1 - 1.3e-33 116.6 0.0 5.4e-32 111.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP10201.1 - 9.9e-09 34.8 0.0 2.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFP10201.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFP10201.1 - 4.6e-06 26.5 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP10201.1 - 1.3e-05 25.3 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KFP10201.1 - 1.4e-05 23.8 0.0 3.3e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 KFP10201.1 - 3.9e-05 22.5 0.0 0.013 14.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KFP10201.1 - 0.00014 22.3 0.0 0.043 14.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFP10201.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KFP10201.1 - 0.0046 16.3 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFP10201.1 - 0.005 16.0 0.0 0.032 13.3 0.0 1.9 1 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KFP10201.1 - 0.011 15.0 0.0 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFP10201.1 - 0.083 12.9 0.2 0.34 10.9 0.2 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_C71 PF12386.8 KFP10201.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei YaiA PF16362.5 KFP10201.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 YaiA protein eIF-3_zeta PF05091.12 KFP10202.1 - 1.6e-216 720.3 4.3 1.8e-216 720.1 4.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KFP10202.1 - 0.00037 20.1 0.0 0.0066 16.0 0.0 2.3 1 1 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus UPF0697 PF15117.6 KFP10202.1 - 0.41 10.8 2.5 14 5.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 PMP22_Claudin PF00822.20 KFP10203.1 - 4.6e-37 127.4 0.4 8.6e-37 126.6 0.4 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP10203.1 - 7.5e-15 55.2 0.5 1.5e-14 54.2 0.5 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 KFP10203.1 - 0.037 14.3 2.0 0.1 12.9 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Ras PF00071.22 KFP10204.1 - 2.5e-35 121.5 0.0 2.9e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10204.1 - 1.9e-16 60.4 0.0 4e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP10204.1 - 0.00032 20.3 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFP10204.1 - 0.00034 20.1 0.0 0.0004 19.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP10204.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KFP10204.1 - 0.12 11.8 0.0 0.66 9.4 0.0 2.3 1 1 0 1 1 1 0 Bacterial TniB protein EF-hand_1 PF00036.32 KFP10205.1 - 3.6e-12 44.9 7.3 2.3e-06 26.8 1.1 2.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFP10205.1 - 6e-12 45.8 0.1 8.2e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP10205.1 - 8.5e-12 44.0 1.7 6.1e-05 22.3 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP10205.1 - 6.4e-10 38.1 3.8 1.2e-05 24.9 0.5 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP10205.1 - 3.6e-09 36.3 1.2 1e-05 25.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP10205.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PX PF00787.24 KFP10206.1 - 3.2e-18 65.8 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KFP10206.1 - 7.2e-15 54.7 0.7 5.9e-14 51.8 0.4 2.2 2 0 0 2 2 2 1 PB1 domain SH3_9 PF14604.6 KFP10206.1 - 1.2e-11 44.3 0.0 2.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP10206.1 - 1.6e-11 43.6 0.1 3.5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP10206.1 - 4.4e-11 42.3 0.0 1.8e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain fn3 PF00041.21 KFP10207.1 - 1.1e-12 48.1 7.4 1.6e-07 31.6 0.0 4.6 4 1 2 6 6 6 2 Fibronectin type III domain Tissue_fac PF01108.17 KFP10207.1 - 1.6e-06 27.9 5.9 0.0001 22.1 0.0 3.3 2 1 1 3 3 3 1 Tissue factor IL4Ra_N PF09238.10 KFP10207.1 - 0.00011 22.5 1.3 0.0021 18.4 0.4 3.0 3 0 0 3 3 3 1 Interleukin-4 receptor alpha chain, N-terminal IL2RB_N1 PF18707.1 KFP10207.1 - 0.018 15.6 5.1 0.064 13.8 0.2 3.2 2 1 0 2 2 2 0 Interleukin-2 receptor subunit beta N-terminal domain 1 SusE PF14292.6 KFP10207.1 - 0.02 15.1 0.6 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 SusE outer membrane protein WAPL PF07814.13 KFP10207.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin IL12p40_C PF10420.9 KFP10207.1 - 0.36 11.4 4.1 0.17 12.4 0.5 2.4 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus IL6Ra-bind PF09240.10 KFP10207.1 - 0.81 10.2 12.4 0.076 13.4 1.3 3.4 3 1 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding TEX33 PF15400.6 KFP10208.1 - 9.1e-35 120.2 0.1 9.8e-35 120.1 0.1 1.0 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family Rhodanese PF00581.20 KFP10209.1 - 5.6e-31 107.2 0.0 3.5e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese PF00581.20 KFP10211.1 - 2.8e-31 108.2 0.0 5.2e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain B12D PF06522.11 KFP10211.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BTB_2 PF02214.22 KFP10212.1 - 5.3e-23 81.2 0.0 8.6e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP10212.1 - 0.017 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-RING_9 PF13901.6 KFP10212.1 - 0.064 13.2 1.1 0.99 9.3 0.0 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon SAM_LFY PF01698.16 KFP10212.1 - 0.065 13.2 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Peptidase_M90 PF06167.12 KFP10212.1 - 0.094 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 fn3 PF00041.21 KFP10213.1 - 1.5e-06 28.5 0.9 2.9e-06 27.5 0.9 1.5 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP10213.1 - 0.057 14.0 2.9 0.22 12.1 2.9 2.0 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Ras PF00071.22 KFP10214.1 - 3.8e-54 182.7 0.0 4.3e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10214.1 - 2.7e-22 79.2 0.0 3.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP10214.1 - 2.3e-07 30.5 0.0 3.8e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Sec7 PF01369.20 KFP10215.1 - 2.3e-69 232.7 0.0 3.4e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFP10215.1 - 1.9e-27 95.8 0.1 3.1e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP10215.1 - 3.8e-05 24.0 0.3 0.00014 22.2 0.3 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFP10215.1 - 0.0028 17.9 0.0 0.31 11.3 0.1 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFP10215.1 - 0.019 15.0 0.0 0.055 13.6 0.0 1.8 1 1 0 1 1 1 0 PH domain Pilosulin PF17499.2 KFP10215.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Ant venom peptides LRR_8 PF13855.6 KFP10216.1 - 2.4e-24 84.8 15.7 6.4e-15 54.7 2.1 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 KFP10216.1 - 2.8e-07 30.6 1.1 8.6e-07 29.0 0.5 2.1 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP10216.1 - 1.1e-06 28.9 12.9 0.007 16.8 0.1 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) fn3 PF00041.21 KFP10216.1 - 0.01 16.1 0.1 0.028 14.8 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain LRR_9 PF14580.6 KFP10216.1 - 0.029 13.9 1.2 0.13 11.7 0.6 2.0 1 1 1 2 2 2 0 Leucine-rich repeat CD34_antigen PF06365.12 KFP10216.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family LRR_1 PF00560.33 KFP10216.1 - 1 10.2 6.8 12 6.9 0.4 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Fringe PF02434.16 KFP10217.1 - 7.4e-112 372.9 0.0 9e-112 372.6 0.0 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KFP10217.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase CARD PF00619.21 KFP10218.1 - 2.4e-20 72.4 0.3 1.1e-19 70.2 0.0 2.4 2 0 0 2 2 2 1 Caspase recruitment domain Guanylate_kin PF00625.21 KFP10218.1 - 0.0012 18.6 1.8 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Guanylate kinase WD40_alt PF14077.6 KFP10218.1 - 0.098 12.5 7.6 0.22 11.4 0.1 4.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif APG6_N PF17675.1 KFP10218.1 - 0.36 11.4 55.2 4.4 7.9 13.4 4.3 1 1 1 3 3 3 0 Apg6 coiled-coil region Mit_KHE1 PF10173.9 KFP10218.1 - 0.66 10.0 5.6 0.24 11.4 1.8 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related HAP1_N PF04849.13 KFP10218.1 - 1.1 8.4 41.9 0.26 10.5 27.4 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region BORG_CEP PF14957.6 KFP10219.1 - 1.1e-15 58.8 1.6 1.9e-10 41.9 1.5 2.2 1 1 1 2 2 2 2 Cdc42 effector PBD PF00786.28 KFP10219.1 - 6.1e-06 26.5 0.1 1.1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Gal-bind_lectin PF00337.22 KFP10220.1 - 2.3e-28 98.4 0.0 2.6e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin VHS PF00790.19 KFP10221.1 - 2.2e-37 128.0 1.5 3.8e-36 124.0 0.0 2.5 2 1 0 2 2 2 1 VHS domain GAT PF03127.14 KFP10221.1 - 1.3e-22 79.9 5.9 1.3e-22 79.9 5.9 2.6 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KFP10221.1 - 6.3e-21 73.7 3.7 6.3e-21 73.7 3.7 2.4 3 0 0 3 3 3 1 GGA N-GAT domain Ferritin PF00210.24 KFP10221.1 - 0.0008 19.4 1.2 0.025 14.5 1.0 2.2 2 0 0 2 2 2 1 Ferritin-like domain Elf4 PF07011.11 KFP10221.1 - 0.0028 17.5 5.1 0.079 12.9 1.5 2.4 2 0 0 2 2 2 2 Early Flowering 4 domain DNA_ligase_A_N PF04675.14 KFP10221.1 - 0.0054 17.1 2.5 3.4 8.0 0.3 2.9 2 1 1 3 3 3 2 DNA ligase N terminus DUF1910 PF08928.10 KFP10221.1 - 0.054 13.5 0.8 0.13 12.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) RsbU_N PF08673.10 KFP10221.1 - 0.076 13.1 1.3 0.25 11.5 0.6 2.2 2 1 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain PCRF PF03462.18 KFP10221.1 - 0.093 12.6 4.3 0.18 11.7 4.3 1.5 1 0 0 1 1 1 0 PCRF domain MCPsignal PF00015.21 KFP10221.1 - 0.1 12.4 2.2 0.15 11.9 2.2 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cytochrom_C_2 PF01322.20 KFP10221.1 - 0.11 13.4 0.1 0.26 12.2 0.0 1.7 1 1 0 1 1 1 0 Cytochrome C' DASH_Dad4 PF08650.10 KFP10221.1 - 0.55 10.2 10.1 0.13 12.2 3.4 3.1 3 1 0 3 3 3 0 DASH complex subunit Dad4 DUF3450 PF11932.8 KFP10221.1 - 0.64 9.3 7.8 1.1 8.5 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Gal-bind_lectin PF00337.22 KFP10222.1 - 9e-28 96.5 0.0 1e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin 7tm_1 PF00001.21 KFP10223.1 - 5.9e-28 97.9 3.5 7.1e-28 97.7 3.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ArfGap PF01412.18 KFP10224.1 - 1.2e-37 128.5 0.2 2.5e-37 127.5 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP10224.1 - 2.9e-21 76.0 0.1 4.3e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 KFP10224.1 - 2.6e-06 27.6 0.6 0.029 14.7 0.0 2.9 3 1 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 KFP10224.1 - 3.1e-06 27.6 1.5 0.00094 19.6 0.8 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFP10224.1 - 3e-05 24.1 0.5 0.0056 16.8 0.1 3.2 2 1 0 2 2 2 1 PH domain PH PF00169.29 KFP10226.1 - 8.6e-17 61.6 0.1 3.3e-16 59.7 0.1 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP10226.1 - 0.00075 19.9 5.5 0.0073 16.7 0.9 3.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFP10226.1 - 0.031 14.4 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 PH domain Zn_ribbon_2 PF12674.7 KFP10226.1 - 0.22 12.2 1.2 0.72 10.6 0.1 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain FAD-SLDH PF12318.8 KFP10226.1 - 0.24 11.5 1.2 0.59 10.2 1.2 1.7 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF3322 PF11795.8 KFP10226.1 - 8.6 6.3 12.0 33 4.4 7.5 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Linker_histone PF00538.19 KFP10227.1 - 5.5e-18 65.1 1.4 1.3e-17 63.9 1.4 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 KFP10227.1 - 5.6 6.7 13.2 6 6.6 13.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Aminotran_1_2 PF00155.21 KFP10228.1 - 4.9e-73 246.4 0.0 5.5e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFP10228.1 - 1.7e-07 30.5 0.0 5.6e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFP10228.1 - 8.9e-05 21.2 0.0 0.00013 20.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KFP10228.1 - 0.0068 15.7 0.1 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase ScsC_N PF18312.1 KFP10228.1 - 0.072 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain DegT_DnrJ_EryC1 PF01041.17 KFP10228.1 - 0.11 11.8 0.3 0.6 9.3 0.3 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 KFP10228.1 - 0.19 10.4 0.0 2.1 7.0 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Ank PF00023.30 KFP10229.1 - 7.5e-22 76.8 8.7 3.3e-09 36.8 0.2 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KFP10229.1 - 3.2e-20 72.5 0.4 3.5e-11 43.5 0.1 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10229.1 - 4.1e-20 71.9 0.6 5.4e-08 33.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP10229.1 - 1e-16 59.3 2.8 4.7e-06 26.5 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFP10229.1 - 2.4e-14 53.2 1.8 1.6e-10 41.0 0.4 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF2520 PF10728.9 KFP10229.1 - 0.038 13.8 0.1 0.14 12.0 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2520) Paf67 PF10255.9 KFP10230.1 - 4.5e-177 589.1 10.5 5.2e-177 588.9 10.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KFP10230.1 - 0.002 18.1 0.4 0.046 13.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP10230.1 - 0.011 15.5 0.3 0.45 10.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP10230.1 - 0.022 15.0 0.1 0.064 13.5 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.7 KFP10230.1 - 0.3 11.2 2.4 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF3585 PF12130.8 KFP10231.1 - 3.6e-47 159.9 14.7 6.3e-47 159.1 14.7 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain LIM PF00412.22 KFP10231.1 - 7.8e-08 32.4 4.1 1.5e-07 31.5 4.1 1.5 1 0 0 1 1 1 1 LIM domain CH PF00307.31 KFP10231.1 - 5e-07 29.9 0.0 8.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Roughex PF06020.11 KFP10231.1 - 0.0012 18.0 4.5 0.0012 18.0 4.5 2.0 2 0 0 2 2 2 1 Drosophila roughex protein UPF0193 PF05250.11 KFP10232.1 - 8.7e-68 228.4 9.0 9.7e-68 228.2 9.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) TMPIT PF07851.13 KFP10232.1 - 0.39 9.9 2.6 0.48 9.6 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein RNA_pol_Rpb6 PF01192.22 KFP10233.1 - 4.2e-16 58.6 0.2 7.4e-16 57.8 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Sox_N PF12444.8 KFP10234.1 - 4.2e-31 107.9 0.5 4.2e-31 107.9 0.5 3.0 3 0 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.19 KFP10234.1 - 4.9e-25 87.7 1.5 8.5e-25 87.0 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP10234.1 - 7.7e-10 39.2 0.9 7.7e-10 39.2 0.9 1.8 2 0 0 2 2 2 1 HMG-box domain Arfaptin PF06456.13 KFP10235.1 - 3.1e-84 282.1 1.6 5e-84 281.4 1.6 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.24 KFP10235.1 - 3.8e-11 43.2 0.2 6.5e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP10235.1 - 4.6e-08 32.8 0.1 8.7e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP10235.1 - 7.7e-06 26.1 1.2 1.4e-05 25.3 0.1 2.0 3 0 0 3 3 3 1 PDZ domain BAR_3 PF16746.5 KFP10235.1 - 3.9e-05 23.5 0.9 0.051 13.3 0.1 2.3 2 0 0 2 2 2 2 BAR domain of APPL family BAR PF03114.18 KFP10235.1 - 4.6e-05 23.2 1.2 0.00065 19.4 1.1 2.3 1 1 0 1 1 1 1 BAR domain GRASP55_65 PF04495.14 KFP10235.1 - 0.025 14.9 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain MFS_1 PF07690.16 KFP10236.1 - 4.5e-32 111.3 25.5 6.7e-32 110.8 25.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily IMD PF08397.11 KFP10237.1 - 3.6e-65 219.4 8.8 4.5e-65 219.1 8.8 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFP10237.1 - 3.4e-10 39.6 0.0 5.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP10237.1 - 0.0002 21.0 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP10237.1 - 0.00034 20.2 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.7 KFP10238.1 - 3.6e-43 146.0 8.0 1.8e-09 38.0 0.1 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10238.1 - 2.4e-30 104.5 4.7 1.1e-05 25.8 0.1 6.7 3 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP10238.1 - 3.4e-30 103.1 8.1 0.00015 22.1 0.1 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFP10238.1 - 4.5e-29 100.1 6.3 1e-07 32.0 0.0 7.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP10238.1 - 9.3e-26 87.1 9.1 0.00047 20.4 0.1 8.4 9 1 0 9 9 9 5 Ankyrin repeat Patatin PF01734.22 KFP10238.1 - 9.9e-19 68.3 1.6 6.4e-18 65.7 1.6 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase bZIP_Maf PF03131.17 KFP10239.1 - 1.1e-32 112.4 8.4 1.4e-32 112.0 8.4 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP10239.1 - 0.00031 20.8 12.5 0.0021 18.1 12.5 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP10239.1 - 0.0076 16.3 10.2 0.0099 15.9 8.5 2.1 1 1 2 3 3 3 1 Basic region leucine zipper DUF1192 PF06698.11 KFP10239.1 - 0.02 14.9 0.1 0.02 14.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.15 KFP10239.1 - 0.027 14.2 1.1 0.027 14.2 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Q_salvage PF10343.9 KFP10239.1 - 0.06 12.9 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Cnn_1N PF07989.11 KFP10239.1 - 0.079 13.1 3.6 0.23 11.6 3.6 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Nup54 PF13874.6 KFP10239.1 - 0.093 12.8 4.2 0.13 12.3 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 YabA PF06156.13 KFP10239.1 - 0.65 10.7 4.1 0.55 10.9 0.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Solute_trans_a PF03619.16 KFP10240.1 - 1.3e-92 310.1 22.6 1.6e-92 309.8 22.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pkinase PF00069.25 KFP10241.1 - 8e-21 74.6 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10241.1 - 1.7e-12 47.2 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP10241.1 - 6.3e-10 38.4 0.1 9.8e-10 37.8 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP10241.1 - 0.00022 21.2 0.1 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFP10241.1 - 0.042 12.8 0.1 0.071 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFP10241.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IRK_C PF17655.1 KFP10242.1 - 1.2e-76 256.2 0.0 2e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP10242.1 - 1.4e-62 209.7 2.9 1.9e-62 209.2 2.9 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFP10242.1 - 0.015 15.5 5.2 0.015 15.5 5.2 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFP10242.1 - 0.11 12.5 12.6 0.18 11.8 11.0 2.1 1 1 1 2 2 2 0 Ion channel DUF92 PF01940.16 KFP10242.1 - 0.13 11.7 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 ER_lumen_recept PF00810.18 KFP10243.1 - 3.3e-54 183.7 11.2 5.7e-54 183.0 11.2 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PrgI PF12666.7 KFP10243.1 - 0.0098 16.6 1.0 0.029 15.1 0.2 2.1 1 1 1 2 2 2 1 PrgI family protein PQ-loop PF04193.14 KFP10243.1 - 0.013 15.2 8.9 0.045 13.5 0.6 3.6 2 1 1 3 3 3 0 PQ loop repeat DUF3810 PF12725.7 KFP10243.1 - 9.3 5.5 13.4 71 2.6 13.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DEAD PF00270.29 KFP10244.1 - 3.2e-50 170.3 0.0 1.9e-49 167.8 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP10244.1 - 3.3e-31 107.9 0.0 1e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP10244.1 - 5.3e-05 23.3 0.0 0.00019 21.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 KFP10244.1 - 0.06 13.2 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_19 PF13245.6 KFP10244.1 - 0.065 13.6 0.0 7.8 6.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ferritin PF00210.24 KFP10244.1 - 0.099 12.6 1.0 0.24 11.3 1.0 1.7 1 1 0 1 1 1 0 Ferritin-like domain Microtub_bind PF13931.6 KFP10244.1 - 0.18 12.2 0.1 0.33 11.3 0.1 1.4 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Rad51 PF08423.11 KFP10245.1 - 6.1e-110 366.5 0.0 8e-110 366.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFP10245.1 - 4.8e-11 42.6 0.0 6.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFP10245.1 - 3.6e-06 26.5 0.1 7.6e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFP10245.1 - 5e-06 26.2 0.0 7.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KFP10245.1 - 2.4e-05 24.9 1.1 4.7e-05 23.9 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain NRD1_2 PF01995.16 KFP10245.1 - 0.0022 17.3 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 DnaB_C PF03796.15 KFP10245.1 - 0.035 13.5 0.1 0.13 11.6 0.1 1.8 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain Chibby PF14645.6 KFP10246.1 - 3.8e-36 124.0 2.2 4.3e-36 123.8 2.2 1.0 1 0 0 1 1 1 1 Chibby family Taxilin PF09728.9 KFP10246.1 - 6.5e-05 22.3 2.8 7.9e-05 22.0 2.8 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein JIP_LZII PF16471.5 KFP10246.1 - 0.13 12.5 8.5 0.17 12.1 8.5 1.2 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II LapA_dom PF06305.11 KFP10246.1 - 0.14 12.0 0.2 0.14 12.0 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TSC22 PF01166.18 KFP10246.1 - 1.8 8.9 9.6 0.31 11.4 4.0 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 KFP10246.1 - 2.7 7.8 7.3 1.3 8.9 2.7 2.0 1 1 1 2 2 2 0 Septum formation initiator Josephin PF02099.17 KFP10247.1 - 5.4e-29 101.4 0.5 1.3e-27 96.9 0.5 2.0 1 1 0 1 1 1 1 Josephin AhpC-TSA PF00578.21 KFP10247.1 - 0.12 12.3 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family GTP_EFTU PF00009.27 KFP10248.1 - 1e-23 83.9 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFP10248.1 - 6.1e-07 29.7 0.7 2.2e-06 27.9 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFP10248.1 - 0.00039 20.7 0.3 0.0021 18.3 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFP10248.1 - 0.0014 18.7 0.1 0.0041 17.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFP10248.1 - 0.0019 18.0 0.0 3.2 7.5 0.0 3.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KFP10248.1 - 0.029 14.3 0.1 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KFP10248.1 - 0.11 12.6 0.2 0.69 10.0 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 KFP10248.1 - 0.17 11.4 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Fam20C PF06702.12 KFP10249.1 - 1.8e-68 230.7 0.0 2.5e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 KFP10249.1 - 0.025 13.4 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 FAM198 protein Dynein_light PF01221.18 KFP10250.1 - 7.4e-28 96.7 0.2 9.3e-28 96.4 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.8 KFP10250.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) GARS_A PF01071.19 KFP10250.1 - 0.047 13.4 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pentaxin PF00354.17 KFP10251.1 - 3.1e-34 118.4 0.0 4.3e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family CBX7_C PF17218.3 KFP10251.1 - 2.3e-14 52.8 1.2 4.9e-14 51.8 1.2 1.6 1 0 0 1 1 1 1 CBX family C-terminal motif Laminin_G_3 PF13385.6 KFP10251.1 - 9.3e-13 48.6 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily YPEB PF14620.6 KFP10251.1 - 0.17 11.2 0.4 0.27 10.5 0.4 1.2 1 0 0 1 1 1 0 YpeB sporulation Chromo PF00385.24 KFP10252.1 - 1.4e-11 44.1 0.7 2.7e-11 43.2 0.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 KFP10252.1 - 5.3e-11 42.0 2.1 1e-10 41.1 2.1 1.4 1 0 0 1 1 1 1 CBX family C-terminal motif PDGF PF00341.17 KFP10254.1 - 4.8e-25 87.7 12.9 8.7e-25 86.8 12.9 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.13 KFP10254.1 - 1.7e-12 47.9 0.5 1.7e-12 47.9 0.5 2.2 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region DUF702 PF05142.12 KFP10254.1 - 9.2 6.7 13.4 26 5.3 13.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF702) Ribosomal_L3 PF00297.22 KFP10255.1 - 2.1e-191 635.7 11.1 2.4e-191 635.5 11.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFP10255.1 - 0.021 14.5 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein DUF3903 PF13043.6 KFP10255.1 - 0.2 11.4 0.7 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) Glyco_transf_17 PF04724.13 KFP10257.1 - 3.4e-29 102.0 1.8 2.4e-24 86.1 0.0 3.3 4 0 0 4 4 4 3 Glycosyltransferase family 17 Mab-21 PF03281.14 KFP10258.1 - 1.6e-16 60.5 0.0 2.3e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 Mab-21 protein bZIP_1 PF00170.21 KFP10259.1 - 6.1e-16 58.3 14.8 6.1e-16 58.3 14.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFP10259.1 - 3.4e-07 30.2 12.4 6.5e-07 29.3 12.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Syntaxin_2 PF14523.6 KFP10259.1 - 0.013 15.8 1.7 0.025 14.9 1.7 1.5 1 0 0 1 1 1 0 Syntaxin-like protein ZapB PF06005.12 KFP10259.1 - 0.015 15.7 3.8 0.015 15.7 3.8 2.1 1 1 1 2 2 2 0 Cell division protein ZapB MCU PF04678.13 KFP10259.1 - 0.13 12.4 0.5 0.29 11.2 0.5 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3450 PF11932.8 KFP10259.1 - 0.14 11.5 8.2 0.25 10.6 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 KFP10259.1 - 0.3 11.1 6.1 0.52 10.3 6.1 1.3 1 0 0 1 1 1 0 Laminin Domain II Atg14 PF10186.9 KFP10259.1 - 0.39 9.8 12.3 0.69 8.9 12.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_Maf PF03131.17 KFP10259.1 - 0.47 11.0 9.4 0.83 10.2 9.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Baculo_F PF12259.8 KFP10259.1 - 0.52 8.8 4.9 0.76 8.2 4.9 1.1 1 0 0 1 1 1 0 Baculovirus F protein UPF0242 PF06785.11 KFP10259.1 - 0.78 9.8 8.6 1.2 9.2 8.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KFP10259.1 - 1.2 8.4 7.9 1.7 7.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KFP10259.1 - 1.5 7.4 10.9 1.9 7.0 10.9 1.1 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.6 KFP10259.1 - 1.6 8.2 7.5 2.4 7.7 7.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF724 PF05266.14 KFP10259.1 - 2.1 8.1 12.7 4 7.2 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0449 PF15136.6 KFP10259.1 - 2.5 8.6 7.5 1.3 9.5 5.1 1.7 2 0 0 2 2 1 0 Uncharacterised protein family UPF0449 OmpH PF03938.14 KFP10259.1 - 5.7 7.3 14.1 8.8 6.7 14.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AROS PF15684.5 KFP10260.1 - 4.7e-29 101.6 3.2 6.2e-29 101.2 3.2 1.1 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 FAM83 PF07894.12 KFP10261.1 - 1.5e-77 260.9 0.1 2.2e-77 260.3 0.1 1.3 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFP10261.1 - 4.4e-07 29.9 0.0 7.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain TNRC6-PABC_bdg PF16608.5 KFP10263.1 - 1.4e-106 356.4 26.5 1.4e-106 356.4 26.5 8.4 4 2 6 10 10 10 1 TNRC6-PABC binding domain Ago_hook PF10427.9 KFP10263.1 - 1.4e-05 25.7 34.9 1.4e-05 25.7 34.9 8.8 2 2 4 7 7 7 1 Argonaute hook SUIM_assoc PF16619.5 KFP10263.1 - 9.4e-05 22.4 0.0 0.23 11.5 0.7 3.7 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 RRM_occluded PF16842.5 KFP10263.1 - 0.00013 21.7 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 KFP10263.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.20 KFP10264.1 - 3.6e-26 92.3 0.0 5.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFP10264.1 - 2.4e-18 66.4 0.0 7e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 KFP10264.1 - 0.06 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DUF4089 PF13318.6 KFP10264.1 - 0.074 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) RabGAP-TBC PF00566.18 KFP10265.1 - 5e-50 170.1 1.7 7.2e-50 169.6 1.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 KFP10265.1 - 2.2e-31 108.6 0.1 5.7e-31 107.3 0.1 1.8 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 KFP10265.1 - 5.5e-12 45.1 0.1 1.3e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP10265.1 - 6e-10 38.8 0.0 1.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP10265.1 - 1.3e-09 37.6 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.15 KFP10266.1 - 3.5e-24 83.7 8.7 2.8e-08 33.2 0.1 3.9 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.27 KFP10266.1 - 6.5e-12 44.9 0.5 1.5e-11 43.7 0.5 1.7 1 0 0 1 1 1 1 SAP domain DUF722 PF05263.11 KFP10266.1 - 0.062 13.5 0.8 0.13 12.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) MPS2 PF17060.5 KFP10266.1 - 0.23 10.7 3.3 0.12 11.6 0.5 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 Mito_carr PF00153.27 KFP10267.1 - 5.4e-53 176.9 1.3 2.1e-22 78.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein STI1 PF17830.1 KFP10269.1 - 2.6e-13 49.7 2.9 2.6e-13 49.7 2.9 2.6 3 0 0 3 3 2 1 STI1 domain TPR_1 PF00515.28 KFP10269.1 - 3.3e-12 45.7 1.4 3.2e-05 23.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP10269.1 - 5.4e-11 41.7 7.7 0.0058 16.7 1.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP10269.1 - 3.1e-09 36.4 0.1 0.00033 20.3 0.0 3.2 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 KFP10269.1 - 5.8e-07 30.1 0.1 0.00027 21.5 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP10269.1 - 4.3e-06 26.7 0.1 0.031 14.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP10269.1 - 7e-06 25.9 0.4 0.028 14.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP10269.1 - 1.2e-05 25.3 3.8 1.3e-05 25.3 0.6 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP10269.1 - 7.6e-05 23.2 6.4 0.02 15.6 0.0 4.3 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP10269.1 - 0.038 14.3 4.5 0.21 11.9 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP10269.1 - 0.049 14.1 4.2 0.39 11.3 0.0 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP10269.1 - 0.073 13.7 0.1 77 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP10269.1 - 0.55 10.4 3.3 29 5.0 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat RhoGEF67_u2 PF16614.5 KFP10269.1 - 0.6 10.2 3.6 1.6 8.8 1.9 2.4 3 0 0 3 3 3 0 Unstructured region two on RhoGEF 6 and 7 Rrn6 PF10214.9 KFP10269.1 - 0.69 8.3 6.8 0.41 9.1 5.0 1.3 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor baeRF_family3 PF18845.1 KFP10269.1 - 0.94 9.7 9.4 6.4 7.0 2.6 3.2 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 Peptidase_M24 PF00557.24 KFP10270.1 - 1.7e-57 194.5 0.0 2.3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFP10270.1 - 4.5e-37 126.5 0.0 8.4e-37 125.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain zf-rbx1 PF12678.7 KFP10272.1 - 6.6e-26 90.4 12.9 7.8e-26 90.1 12.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP10272.1 - 1.1e-15 57.5 10.7 1.3e-15 57.2 10.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFP10272.1 - 5.4e-07 29.8 14.9 2.9e-05 24.3 14.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP10272.1 - 2.3e-05 24.1 3.2 2.3e-05 24.1 3.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP10272.1 - 0.00038 20.3 12.2 0.0083 16.0 12.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP10272.1 - 0.031 14.1 11.4 0.17 11.8 5.2 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFP10272.1 - 0.039 13.6 5.3 0.039 13.6 5.3 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFP10272.1 - 0.14 12.4 9.4 0.87 9.8 9.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KFP10272.1 - 0.14 11.9 16.6 17 5.2 16.6 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP10272.1 - 0.17 11.9 8.3 0.71 9.9 8.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP10272.1 - 3.1 8.0 9.4 0.39 10.9 0.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP10272.1 - 3.9 7.5 13.6 40 4.3 13.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 KFP10272.1 - 4.2 7.7 13.0 52 4.3 13.0 2.3 1 1 0 1 1 1 0 RING-like domain MBT PF02820.18 KFP10275.1 - 1.7e-98 323.0 5.0 1.2e-27 96.0 0.2 4.4 4 0 0 4 4 4 4 mbt repeat zf-CCCH PF00642.24 KFP10276.1 - 1.2e-12 47.4 27.7 2.1e-05 24.3 2.4 4.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_1 PF00515.28 KFP10276.1 - 8.3e-06 25.4 1.0 2.6e-05 23.8 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP10276.1 - 0.00015 21.6 1.4 0.0019 18.2 0.8 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP10276.1 - 0.00046 20.4 1.1 0.0017 18.6 0.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-C2H2_2 PF12756.7 KFP10276.1 - 0.0019 18.5 0.8 0.0081 16.5 0.8 2.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-CCCH_4 PF18044.1 KFP10276.1 - 0.021 14.6 0.9 0.021 14.6 0.9 4.5 4 0 0 4 4 4 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP10276.1 - 0.022 14.8 0.8 0.022 14.8 0.8 4.7 4 0 0 4 4 4 0 Zinc finger domain TPR_8 PF13181.6 KFP10276.1 - 0.035 14.3 0.6 0.087 13.1 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.8 KFP10276.1 - 0.58 10.5 12.9 0.065 13.5 7.5 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2043 PF09740.9 KFP10276.1 - 5.8 7.6 11.3 3.9 8.2 1.3 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2043) bZIP_2 PF07716.15 KFP10277.1 - 9.6e-16 57.6 11.9 9.6e-16 57.6 11.9 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP10277.1 - 3.2e-06 27.1 7.9 6.1e-06 26.2 7.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFP10277.1 - 0.011 15.9 0.5 0.026 14.7 0.5 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 KFP10277.1 - 0.037 14.5 5.4 0.087 13.3 5.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor PHF5 PF03660.14 KFP10278.1 - 1.5e-40 137.6 14.1 1.7e-40 137.4 14.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KFP10278.1 - 0.056 11.3 8.0 0.057 11.3 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Aconitase PF00330.20 KFP10279.1 - 1.7e-148 495.5 0.0 2.1e-148 495.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFP10279.1 - 4.6e-46 156.4 0.0 9.1e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RNA_pol_Rbc25 PF08292.12 KFP10280.1 - 5e-44 149.7 0.1 7.7e-44 149.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFP10280.1 - 4.4e-20 71.8 0.1 9.1e-20 70.8 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CSD PF00313.22 KFP10281.1 - 3.5e-14 52.4 0.1 4.4e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFP10281.1 - 0.00087 18.9 0.1 0.0013 18.3 0.1 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain PMM PF03332.13 KFP10282.1 - 3.3e-96 321.3 0.2 3.7e-96 321.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Peptidase_C97 PF05903.14 KFP10283.1 - 2.5e-36 124.8 0.0 2.8e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Ku_N PF03731.15 KFP10284.1 - 5.4e-72 242.1 0.0 9.6e-72 241.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 KFP10284.1 - 2.3e-58 197.3 0.2 3.9e-58 196.5 0.2 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SAP PF02037.27 KFP10284.1 - 1.8e-10 40.3 0.1 3.7e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 KFP10284.1 - 1.4e-08 35.3 0.1 6.6e-08 33.1 0.1 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ribosomal_L7Ae PF01248.26 KFP10285.1 - 5.3e-26 90.2 0.1 6.6e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFP10285.1 - 0.00031 20.8 0.1 0.00035 20.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFP10285.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain ERK-JNK_inhib PF15002.6 KFP10287.1 - 6.4e-63 212.0 0.0 7.7e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor BaffR-Tall_bind PF09256.10 KFP10288.1 - 8e-07 28.7 2.7 2.1e-06 27.4 2.7 1.7 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding COX16 PF14138.6 KFP10288.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 CENP-M PF11111.8 KFP10289.1 - 1.3e-70 236.1 0.1 1.4e-70 236.0 0.1 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Septin PF00735.18 KFP10290.1 - 5.4e-116 386.8 1.6 6.3e-116 386.6 1.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP10290.1 - 3.8e-08 33.4 0.0 6.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP10290.1 - 2.9e-06 27.3 3.7 2.3e-05 24.3 1.4 2.5 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP10290.1 - 2e-05 24.2 0.5 0.013 15.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP10290.1 - 3.7e-05 23.2 0.1 6.8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFP10290.1 - 0.00034 20.7 7.0 0.081 13.0 0.8 3.4 2 2 2 4 4 4 2 Dynamin family AAA_16 PF13191.6 KFP10290.1 - 0.00086 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KFP10290.1 - 0.0012 19.4 0.2 0.0042 17.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 KFP10290.1 - 0.0013 19.0 0.2 0.0029 17.8 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KFP10290.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 KFP10290.1 - 0.0044 16.6 0.2 0.014 15.0 0.1 1.9 1 1 0 2 2 2 1 Ras family AAA_24 PF13479.6 KFP10290.1 - 0.0046 16.7 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFP10290.1 - 0.0065 15.7 0.9 0.0083 15.3 0.2 1.6 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFP10290.1 - 0.0067 15.8 0.8 0.0088 15.4 0.1 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 KFP10290.1 - 0.018 14.7 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFP10290.1 - 0.024 13.8 3.6 0.074 12.2 3.6 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Sigma54_activat PF00158.26 KFP10290.1 - 0.031 14.0 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KFP10290.1 - 0.032 14.0 0.1 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 KFP10290.1 - 0.046 12.8 0.8 0.091 11.8 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 KFP10290.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KFP10290.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KFP10290.1 - 0.097 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFP10290.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFP10290.1 - 0.16 12.1 0.1 0.51 10.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KFP10290.1 - 0.18 11.9 1.0 0.37 10.9 0.2 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain GRAM PF02893.20 KFP10291.1 - 3.3e-14 52.8 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Complex1_LYR PF05347.15 KFP10292.1 - 8.3e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4252 PF14060.6 KFP10292.1 - 0.067 13.1 0.2 0.081 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) p450 PF00067.22 KFP10293.1 - 2.5e-125 418.8 0.1 8.8e-125 417.0 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-HC5HC2H PF13771.6 KFP10294.1 - 7.9e-09 35.7 6.8 2.4e-08 34.1 6.8 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP10294.1 - 2.3e-08 34.2 1.9 6.7e-08 32.7 1.9 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain SH2 PF00017.24 KFP10295.1 - 2.9e-06 27.3 0.0 3.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Abhydrolase_1 PF00561.20 KFP10296.1 - 1.8e-21 76.9 0.3 1.2e-20 74.2 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP10296.1 - 1.6e-17 64.9 0.3 2.1e-17 64.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP10296.1 - 1e-12 47.8 0.0 3.8e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFP10296.1 - 0.013 15.6 0.4 0.23 11.5 0.1 2.3 2 1 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 KFP10296.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFP10296.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KFP10296.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KFP10296.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.8 1 1 0 1 1 1 0 Putative esterase RRP7 PF12923.7 KFP10297.1 - 1.1e-35 122.3 11.1 1.6e-35 121.8 11.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 KFP10297.1 - 0.0025 18.1 0.7 0.0059 16.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5093) RRM_1 PF00076.22 KFP10297.1 - 0.033 14.0 0.1 2.2 8.2 0.0 2.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trans_reg_C PF00486.28 KFP10297.1 - 0.059 13.5 1.4 0.28 11.3 0.7 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Vir_act_alpha_C PF10400.9 KFP10297.1 - 0.17 12.6 0.1 0.17 12.6 0.1 2.5 2 1 0 2 2 2 0 Virulence activator alpha C-term Atg14 PF10186.9 KFP10297.1 - 1.5 7.8 4.9 2 7.4 4.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRM_1 PF00076.22 KFP10298.1 - 1.2e-10 41.1 0.0 3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIEAP PF16026.5 KFP10299.1 - 0.00062 20.0 0.2 0.00075 19.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondria-eating protein DUF807 PF05660.11 KFP10299.1 - 0.063 13.3 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) Globin PF00042.22 KFP10300.1 - 5.7e-31 107.3 0.2 1.1e-30 106.5 0.1 1.4 2 0 0 2 2 2 1 Globin BEN PF10523.9 KFP10300.1 - 0.035 14.3 0.0 0.089 13.0 0.0 1.7 2 0 0 2 2 2 0 BEN domain IL12 PF03039.14 KFP10300.1 - 0.057 12.8 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit LUC7 PF03194.15 KFP10301.1 - 2.1e-70 237.3 13.3 2.1e-70 237.3 13.3 2.1 1 1 1 2 2 2 1 LUC7 N_terminus PAP1 PF08601.10 KFP10301.1 - 0.53 9.9 6.1 0.7 9.6 6.0 1.5 1 1 0 1 1 1 0 Transcription factor PAP1 UBN_AB PF14075.6 KFP10303.1 - 6.4e-82 274.4 4.1 6.4e-82 274.4 4.1 2.4 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KFP10303.1 - 1.7e-19 69.5 0.4 4e-19 68.3 0.4 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain TPR_19 PF14559.6 KFP10304.1 - 4.4e-17 62.4 10.8 2.4e-05 24.8 0.5 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP10304.1 - 7.6e-10 38.9 22.7 0.0014 18.8 0.3 5.3 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP10304.1 - 9.8e-09 34.7 28.1 0.029 14.5 0.3 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP10304.1 - 3.2e-08 33.2 7.3 0.0048 17.0 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP10304.1 - 3.3e-08 33.7 6.6 0.99 10.4 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP10304.1 - 2.4e-06 28.1 5.5 0.14 12.8 0.1 5.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP10304.1 - 4.1e-06 26.9 2.3 0.013 15.6 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP10304.1 - 2.2e-05 24.8 12.4 0.059 14.0 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP10304.1 - 7.2e-05 22.9 5.7 0.019 15.3 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP10304.1 - 0.00015 21.6 10.3 1.2 9.3 0.3 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP10304.1 - 0.00022 20.9 20.4 0.011 15.5 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat PPR PF01535.20 KFP10304.1 - 0.00082 19.5 0.3 5.3 7.5 0.0 4.5 4 0 0 4 4 4 1 PPR repeat TPR_4 PF07721.14 KFP10304.1 - 0.0016 18.8 0.0 24 5.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP10304.1 - 0.0019 18.5 16.1 1 9.7 0.0 6.4 6 2 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP10304.1 - 0.0061 16.2 0.1 0.065 12.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat PyocinActivator PF11112.8 KFP10304.1 - 0.019 15.1 0.1 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 Pyocin activator protein PrtN PPR_2 PF13041.6 KFP10304.1 - 0.022 15.0 0.6 4.9 7.4 0.1 3.5 3 1 1 4 4 4 0 PPR repeat family TPR_10 PF13374.6 KFP10304.1 - 0.51 10.3 14.6 14 5.7 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP10304.1 - 0.76 9.9 5.6 6 7.0 0.2 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Guanylate_cyc PF00211.20 KFP10305.1 - 1.3e-65 220.4 0.0 3.9e-65 218.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFP10305.1 - 1e-34 120.0 0.0 3e-34 118.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP10305.1 - 3.3e-28 98.8 0.1 7e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 KFP10305.1 - 1.4e-05 24.4 0.1 0.00034 19.8 0.0 2.2 2 0 0 2 2 2 1 Receptor family ligand binding region Phospholip_B PF04916.13 KFP10307.1 - 2.9e-186 620.2 2.9 3.2e-186 620.0 2.9 1.0 1 0 0 1 1 1 1 Phospholipase B Nucleo_LEF-12 PF06256.11 KFP10307.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein ATF7IP_BD PF16788.5 KFP10308.1 - 1.6e-75 254.0 6.4 1.6e-75 254.0 6.4 4.7 5 1 1 6 6 6 1 ATF-interacting protein binding domain fn3_4 PF16794.5 KFP10308.1 - 3.6e-40 136.0 0.0 6.8e-40 135.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-III type domain NMDAR2_C PF10565.9 KFP10309.1 - 1.4e-227 757.8 13.6 1.7e-227 757.5 13.6 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.26 KFP10309.1 - 1.3e-33 116.0 0.1 2.1e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP10309.1 - 7.9e-31 106.6 0.1 5.5e-30 103.9 0.1 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP10309.1 - 1.1e-24 87.1 0.0 1.8e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFP10309.1 - 9.2e-11 41.4 0.0 8.3e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region DUF4013 PF13197.6 KFP10309.1 - 3.2 7.5 6.9 3.5 7.4 4.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) 7tm_4 PF13853.6 KFP10311.1 - 1.8e-15 57.4 2.1 2e-15 57.3 2.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP10311.1 - 0.27 10.5 3.0 0.35 10.2 3.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP10312.1 - 3.4e-44 151.7 14.3 3.9e-44 151.5 14.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP10312.1 - 1.9e-29 102.8 15.3 2.6e-29 102.4 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP10312.1 - 0.00033 20.1 10.9 0.00051 19.5 10.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CholecysA-Rec_N PF09193.10 KFP10312.1 - 0.079 13.0 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal Hexapep PF00132.24 KFP10313.1 - 0.00033 20.2 14.1 0.0026 17.4 3.3 4.0 4 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) RRM_1 PF00076.22 KFP10314.1 - 5.8e-12 45.2 0.0 8.9e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIE_beta PF02186.15 KFP10315.1 - 7.1e-22 77.5 0.2 7.1e-22 77.5 0.2 2.3 3 0 0 3 3 3 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 KFP10315.1 - 2.4e-10 40.0 0.1 5.4e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 PDZ PF00595.24 KFP10315.1 - 0.043 14.2 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 PDZ domain EF-hand_11 PF08976.11 KFP10315.1 - 0.045 14.6 0.0 0.081 13.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain DUF4713 PF15831.5 KFP10316.1 - 7.8e-22 77.5 7.2 9.5e-22 77.2 7.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) EVC2_like PF12297.8 KFP10316.1 - 0.074 11.7 0.1 0.075 11.7 0.1 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Helicase_C PF00271.31 KFP10317.1 - 2.7e-18 66.4 0.0 4.9e-17 62.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 KFP10317.1 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 KFP10317.1 - 5.2e-16 58.9 0.0 9.9e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase HTH_40 PF14493.6 KFP10317.1 - 2.9e-12 46.9 0.0 6.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HRDC PF00570.23 KFP10317.1 - 2.4e-11 43.4 0.1 5.2e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 KFP10317.1 - 3.5e-08 34.1 1.5 8.5e-08 32.8 1.5 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFP10317.1 - 0.0004 20.4 0.0 0.00091 19.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MHC_I_3 PF16497.5 KFP10318.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 MHC-I family domain C1-set PF07654.15 KFP10318.1 - 1.4e-15 57.5 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_I PF00129.18 KFP10318.1 - 6.3e-10 38.9 0.0 8.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Ig_3 PF13927.6 KFP10318.1 - 2.5e-05 24.8 0.0 4.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFP10318.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KFP10318.1 - 0.0048 17.2 0.0 0.0098 16.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP10318.1 - 0.068 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 KFP10318.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain BicD PF09730.9 KFP10319.1 - 0 1184.2 69.3 0 1183.8 69.3 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.12 KFP10319.1 - 0.0068 16.5 7.2 0.0068 16.5 7.2 7.0 5 2 2 7 7 7 4 TPR/MLP1/MLP2-like protein DUF1759 PF03564.15 KFP10319.1 - 0.0087 16.0 7.4 0.0087 16.0 7.4 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF1759) NPV_P10 PF05531.12 KFP10319.1 - 0.035 14.6 1.8 0.035 14.6 1.8 7.3 5 4 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Get5_bdg PF16843.5 KFP10319.1 - 0.039 13.5 0.3 2.4 7.7 0.1 3.0 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein ApoO PF09769.9 KFP10319.1 - 0.3 11.0 21.4 0.16 12.0 0.5 4.9 4 3 1 5 5 5 0 Apolipoprotein O Mce4_CUP1 PF11887.8 KFP10319.1 - 4 6.8 9.7 9.7 5.6 1.7 3.4 4 0 0 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF725 PF05267.12 KFP10319.1 - 4.1 7.4 17.0 0.4 10.7 1.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF725) DUF1796 PF08795.10 KFP10319.1 - 6.3 6.7 8.7 1.3 9.0 0.1 3.7 4 0 0 4 4 4 0 Putative papain-like cysteine peptidase (DUF1796) RhoGEF PF00621.20 KFP10320.1 - 1.8e-47 161.9 3.8 2.9e-47 161.3 0.6 2.3 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP10320.1 - 4.5e-23 81.8 0.2 3.1e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 PH domain FYVE PF01363.21 KFP10320.1 - 4.5e-14 52.3 14.7 8.1e-13 48.3 15.4 2.5 2 0 0 2 2 2 1 FYVE zinc finger PH_13 PF16652.5 KFP10320.1 - 0.0003 20.6 1.8 0.073 12.9 2.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFP10320.1 - 0.00033 20.6 1.6 0.00048 20.1 0.5 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP10320.1 - 0.026 14.9 0.4 1.9 8.9 0.1 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 KFP10320.1 - 0.075 12.9 1.2 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 PH domain PH_9 PF15410.6 KFP10320.1 - 0.11 12.9 3.1 7.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain FYVE_2 PF02318.16 KFP10320.1 - 1.2 9.3 23.0 0.061 13.5 13.1 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger Sushi PF00084.20 KFP10322.1 - 1.3e-05 25.7 0.1 2.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF728 PF05304.12 KFP10322.1 - 0.0049 16.7 0.4 0.0072 16.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF728) Shisa PF13908.6 KFP10322.1 - 0.014 15.7 0.4 0.016 15.5 0.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CARD PF00619.21 KFP10323.1 - 1.8e-07 31.0 0.2 2.9e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Cytokin_check_N PF10407.9 KFP10323.1 - 0.017 15.1 1.3 5.8 7.0 0.2 2.5 2 1 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus NADH5_C PF06455.11 KFP10323.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus DUF2732 PF10809.8 KFP10323.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Ninjurin PF04923.12 KFP10324.1 - 4.6e-37 126.1 5.4 5.3e-37 125.9 5.4 1.0 1 0 0 1 1 1 1 Ninjurin DSPc PF00782.20 KFP10330.1 - 3.8e-12 46.2 0.0 9.5e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP10330.1 - 2.7e-08 33.7 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KFP10330.1 - 0.00028 20.6 0.0 0.0013 18.5 0.1 1.9 1 1 1 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KFP10330.1 - 0.0037 17.3 0.0 0.0092 16.0 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family His_Phos_1 PF00300.22 KFP10333.1 - 1.5e-34 119.4 0.0 6.9e-27 94.4 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.21 KFP10334.1 - 1.3e-51 175.5 0.0 2.3e-51 174.8 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 KFP10334.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Development and cell death domain DUF1456 PF07308.13 KFP10334.1 - 0.19 12.1 0.2 1.7 9.0 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) Aldo_ket_red PF00248.21 KFP10335.1 - 4.2e-53 180.5 0.0 6.2e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family UCH PF00443.29 KFP10337.1 - 2.1e-39 135.6 2.5 2.6e-39 135.3 2.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP10337.1 - 1.1e-24 87.6 14.0 2.4e-24 86.5 14.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAN_3 PF08277.12 KFP10337.1 - 0.053 13.3 2.8 2.9 7.8 4.2 2.4 2 0 0 2 2 2 0 PAN-like domain Tubulin PF00091.25 KFP10338.1 - 7.5e-67 225.3 0.0 1.1e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP10338.1 - 3.3e-46 156.5 0.0 5.7e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP10338.1 - 0.0016 18.2 0.0 0.0038 16.9 0.0 1.6 1 1 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KFP10339.1 - 4.7e-66 222.8 0.0 6.1e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP10339.1 - 1.9e-36 125.0 0.0 3.5e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP10339.1 - 0.0018 18.0 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Pex26 PF07163.12 KFP10340.1 - 1.8e-94 316.4 6.5 2.2e-94 316.2 6.5 1.0 1 0 0 1 1 1 1 Pex26 protein CH PF00307.31 KFP10341.1 - 1.4e-20 73.5 0.0 4.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP10341.1 - 6.1e-13 48.4 0.0 1.9e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.22 KFP10341.1 - 8.7e-09 35.5 10.1 1.7e-08 34.6 10.1 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.19 KFP10341.1 - 1.1e-05 24.9 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFP10341.1 - 4.5e-05 22.9 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP10341.1 - 0.00019 20.8 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP10341.1 - 0.00067 18.5 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KFP10341.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KFP10341.1 - 0.003 18.0 0.0 0.01 16.3 0.0 1.9 2 0 0 2 2 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFP10341.1 - 0.0041 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFP10341.1 - 0.0051 17.3 0.0 0.02 15.4 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFP10341.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFP10341.1 - 0.026 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFP10341.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFP10341.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3585 PF12130.8 KFP10342.1 - 2.6e-49 166.8 28.8 6.8e-49 165.5 28.8 1.8 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain BID PF06393.11 KFP10344.1 - 8.1e-71 237.5 1.2 8.9e-71 237.4 1.2 1.0 1 0 0 1 1 1 1 BH3 interacting domain (BID) Bcl-2 PF00452.19 KFP10344.1 - 0.00045 20.8 0.2 0.00069 20.3 0.2 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family DUF3349 PF11829.8 KFP10344.1 - 0.041 14.7 0.6 0.078 13.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) Clathrin-link PF09268.10 KFP10344.1 - 0.056 12.8 1.8 0.094 12.1 0.8 2.0 2 0 0 2 2 2 0 Clathrin, heavy-chain linker DUF2573 PF10835.8 KFP10344.1 - 0.14 12.6 0.1 0.36 11.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) Bcl-2 PF00452.19 KFP10345.1 - 8.9e-12 45.6 0.0 1.5e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family T3SS_needle_E PF08988.10 KFP10345.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.3 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF4549 PF15082.6 KFP10345.1 - 0.045 13.5 2.0 0.13 12.0 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) DUF842 PF05811.13 KFP10345.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) vATP-synt_E PF01991.18 KFP10346.1 - 5.2e-76 254.5 12.0 5.9e-76 254.3 12.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 KFP10346.1 - 0.014 15.8 2.4 0.02 15.3 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Par3_HAL_N_term PF12053.8 KFP10346.1 - 0.018 15.2 2.7 0.93 9.8 0.0 2.8 2 1 1 3 3 3 0 N-terminal of Par3 and HAL proteins ATP-synt_B PF00430.18 KFP10346.1 - 0.045 13.8 15.4 0.11 12.6 0.6 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) NifW PF03206.14 KFP10346.1 - 0.18 12.3 3.5 0.25 11.9 2.4 1.7 1 1 0 1 1 1 0 Nitrogen fixation protein NifW A_deaminase PF00962.22 KFP10347.1 - 1.8e-20 73.6 0.0 2.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KFP10347.1 - 9.3e-16 57.9 0.1 2.9e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal IL17R_fnIII_D1 PF16556.5 KFP10348.1 - 7.3e-61 204.3 1.2 1.5e-60 203.3 1.2 1.6 1 0 0 1 1 1 1 Interleukin-17 receptor, fibronectin-III-like domain 1 SEFIR PF08357.11 KFP10348.1 - 1.5e-43 148.6 0.0 3e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 SEFIR domain IL17R_fnIII_D2 PF16578.5 KFP10348.1 - 1.1e-39 135.1 0.6 3.6e-39 133.5 0.6 1.9 1 0 0 1 1 1 1 Interleukin 17 receptor D VGCC_alpha2 PF08473.11 KFP10352.1 - 6.2e-38 130.7 0.4 9.1e-34 117.0 0.2 2.1 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 KFP10352.1 - 4.2e-37 127.4 0.1 7.6e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 VWA N-terminal VWA_3 PF13768.6 KFP10352.1 - 3.5e-15 56.3 0.0 7.2e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFP10352.1 - 1.1e-12 48.5 0.0 1.8e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFP10352.1 - 1.5e-12 47.9 1.4 4.3e-10 39.8 0.0 3.4 3 1 0 3 3 3 1 Cache domain VWA_2 PF13519.6 KFP10352.1 - 5.4e-11 43.1 0.0 1.1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP10352.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.8 KFP10352.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain LRR_8 PF13855.6 KFP10353.1 - 2.7e-24 84.7 26.3 2e-12 46.7 1.1 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP10353.1 - 1.7e-11 44.2 17.7 0.0013 19.1 2.9 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFP10353.1 - 4.8e-09 35.7 3.3 4.8e-09 35.7 3.3 2.3 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFP10353.1 - 3.4e-08 33.5 0.0 5e-07 29.7 0.0 2.4 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP10353.1 - 5.1e-05 22.8 4.1 0.00032 20.3 3.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP10353.1 - 0.007 16.8 17.7 0.034 14.7 0.7 5.1 4 1 0 4 4 4 1 Leucine Rich Repeat Shisa PF13908.6 KFP10353.1 - 0.0076 16.5 0.3 0.013 15.7 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRR_6 PF13516.6 KFP10353.1 - 2.5 8.4 9.6 52 4.3 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat HlyIII PF03006.20 KFP10354.1 - 2.8e-72 243.1 21.2 3.5e-72 242.8 21.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 KFP10354.1 - 0.29 11.3 1.0 1.5 9.0 1.0 2.2 1 1 0 1 1 1 0 Low psii accumulation1 / Rep27 NOP19 PF10863.8 KFP10355.1 - 0.2 11.5 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleolar protein 19 wnt PF00110.19 KFP10356.1 - 3.2e-114 381.7 19.2 3.6e-114 381.5 19.2 1.0 1 0 0 1 1 1 1 wnt family Cast PF10174.9 KFP10358.1 - 0 1085.1 144.8 0 1085.0 144.8 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.11 KFP10358.1 - 0.002 17.1 16.5 0.002 17.1 16.5 7.5 1 1 7 8 8 8 4 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KFP10358.1 - 0.0022 17.8 0.6 0.0022 17.8 0.6 12.5 14 2 2 16 16 16 3 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_13 PF13166.6 KFP10358.1 - 0.0024 16.6 25.2 0.0024 16.6 25.2 5.3 1 1 3 4 4 4 1 AAA domain Troponin PF00992.20 KFP10358.1 - 0.0058 16.9 20.6 0.0058 16.9 20.6 8.2 2 2 4 7 7 7 1 Troponin Fib_alpha PF08702.10 KFP10358.1 - 0.015 15.5 11.9 0.015 15.5 11.9 8.5 2 2 6 9 9 9 0 Fibrinogen alpha/beta chain family DUF5617 PF18493.1 KFP10358.1 - 0.78 9.9 4.9 0.59 10.3 0.3 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5617) Phage_tail_NK PF16532.5 KFP10358.1 - 4.9 6.8 7.7 8.3 6.0 0.5 3.5 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales Cgr1 PF03879.14 KFP10360.1 - 3.4e-08 33.8 18.1 3.5e-08 33.8 18.1 1.0 1 0 0 1 1 1 1 Cgr1 family TAF4 PF05236.14 KFP10360.1 - 0.17 11.6 12.6 0.18 11.5 12.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ESM4 PF15952.5 KFP10360.1 - 0.39 11.1 5.9 0.45 10.9 5.9 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family US6 PF17616.2 KFP10360.1 - 0.42 10.6 2.0 0.46 10.4 2.0 1.1 1 0 0 1 1 1 0 Viral unique short region 6 Bile_Hydr_Trans PF04775.14 KFP10361.1 - 3.4e-34 117.6 0.0 3.7e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.11 KFP10362.1 - 8.4e-54 182.7 0.0 9.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KFP10362.1 - 1.9e-05 24.4 0.0 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 KFP10362.1 - 0.0051 16.5 0.0 0.023 14.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) COS PF18568.1 KFP10363.1 - 5.8e-24 83.8 0.4 3.1e-23 81.5 0.3 2.1 2 0 0 2 2 2 1 TRIM C-terminal subgroup One Signature domain SPRY PF00622.28 KFP10363.1 - 8.6e-13 48.5 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP10363.1 - 2.1e-07 30.5 0.0 9.2e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 SPRY-associated domain zf-B_box PF00643.24 KFP10363.1 - 2.8e-05 24.2 15.1 0.00058 19.9 0.5 3.0 3 0 0 3 3 3 2 B-box zinc finger CEBP_ZZ PF16366.5 KFP10363.1 - 0.005 17.0 2.9 0.021 15.1 2.9 2.0 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-HC5HC2H_2 PF13832.6 KFP10365.1 - 4.2e-37 126.7 4.5 4.2e-37 126.7 4.5 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP10365.1 - 3.3e-26 91.4 2.9 3.3e-26 91.4 2.9 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFP10365.1 - 2.1e-25 88.6 0.4 5.2e-25 87.3 0.4 1.7 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.9 KFP10365.1 - 1.1e-24 87.6 8.7 1.1e-24 87.6 8.7 3.5 3 2 0 3 3 3 1 Enhancer of polycomb-like PWWP PF00855.17 KFP10365.1 - 4.4e-18 65.5 0.0 2.2e-17 63.2 0.0 2.3 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 KFP10365.1 - 1.9e-13 49.7 4.4 1.9e-13 49.7 4.4 3.0 2 1 0 2 2 2 1 PHD-finger PHD PF00628.29 KFP10365.1 - 6.3e-07 29.2 27.9 2.6e-06 27.2 13.4 2.9 2 0 0 2 2 2 2 PHD-finger AAA_23 PF13476.6 KFP10365.1 - 0.0065 17.0 6.0 0.039 14.5 1.3 2.7 2 0 0 2 2 2 1 AAA domain DUF3439 PF11921.8 KFP10365.1 - 0.075 13.0 1.4 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DNA_topoisoIV PF00521.20 KFP10365.1 - 0.11 11.4 4.1 0.2 10.5 4.1 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A zf-BED PF02892.15 KFP10366.1 - 1.2e-63 210.9 29.5 1.8e-16 59.9 0.4 4.7 4 0 0 4 4 4 4 BED zinc finger Dimer_Tnp_hAT PF05699.14 KFP10366.1 - 8.1e-11 41.6 3.6 1.2e-10 41.0 0.5 2.9 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PyrI_C PF02748.15 KFP10366.1 - 6.9e-05 22.7 5.0 2.5 8.1 0.1 4.5 4 0 0 4 4 4 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_12 PF18658.1 KFP10366.1 - 0.25 10.9 12.4 1.1 8.8 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KFP10366.1 - 5.7 7.3 9.1 41 4.6 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon Glyco_transf_22 PF03901.17 KFP10367.1 - 1e-42 146.9 29.8 1.3e-42 146.6 29.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EGF_CA PF07645.15 KFP10368.1 - 2.9e-14 53.0 33.0 3.7e-11 43.0 11.1 7.2 4 2 2 6 6 6 2 Calcium-binding EGF domain DUF3456 PF11938.8 KFP10368.1 - 4.4e-06 27.3 6.7 0.00026 21.5 1.7 3.1 3 1 1 4 4 4 2 TLR4 regulator and MIR-interacting MSAP cEGF PF12662.7 KFP10368.1 - 0.00016 21.6 10.2 0.001 18.9 2.0 6.8 5 1 0 5 5 5 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 KFP10368.1 - 0.00086 19.6 10.8 0.00086 19.6 10.8 5.6 3 2 1 4 4 4 1 Pvs28 EGF domain VSP PF03302.13 KFP10368.1 - 0.0011 17.9 62.8 0.067 12.0 29.2 3.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein EGF PF00008.27 KFP10368.1 - 0.0018 18.5 0.9 0.0018 18.5 0.9 6.7 8 1 1 9 9 9 2 EGF-like domain hEGF PF12661.7 KFP10368.1 - 0.0022 18.6 0.9 0.0022 18.6 0.9 8.1 7 2 0 7 7 7 1 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 KFP10368.1 - 0.014 15.4 4.4 0.014 15.4 4.4 5.1 4 1 1 5 5 5 0 MSP1 EGF domain 1 DUF1387 PF07139.11 KFP10369.1 - 5.9e-115 384.3 6.5 6.6e-115 384.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) DUF5349 PF17298.2 KFP10369.1 - 0.1 12.3 1.3 0.15 11.8 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) IRK_N PF08466.10 KFP10369.1 - 0.13 12.4 1.3 0.21 11.8 0.3 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal BEN PF10523.9 KFP10370.1 - 2.1e-12 47.1 0.0 4.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 BEN domain bZIP_2 PF07716.15 KFP10370.1 - 0.056 13.5 0.3 0.17 12.0 0.3 1.9 1 0 0 1 1 1 0 Basic region leucine zipper DUF1087 PF06465.13 KFP10370.1 - 0.059 13.4 0.4 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Spectrin PF00435.21 KFP10372.1 - 2.7e-225 731.7 490.2 1.1e-16 61.2 7.7 42.6 40 4 4 44 44 42 33 Spectrin repeat CH PF00307.31 KFP10372.1 - 7.7e-37 125.8 8.7 9.9e-19 67.5 0.0 6.2 6 0 0 6 6 5 2 Calponin homology (CH) domain GAS2 PF02187.17 KFP10372.1 - 2.8e-30 104.2 0.4 1.1e-29 102.3 0.4 2.2 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin_like PF18373.1 KFP10372.1 - 1.2e-29 102.2 1.0 1.2e-29 102.2 1.0 10.0 13 0 0 13 13 9 1 Spectrin like domain SH3_10 PF17902.1 KFP10372.1 - 3.3e-20 71.9 0.2 1.1e-19 70.3 0.2 2.0 1 0 0 1 1 1 1 SH3 domain EF-hand_1 PF00036.32 KFP10372.1 - 8.8e-12 43.7 2.3 0.0001 21.6 0.8 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP10372.1 - 8e-11 41.0 1.6 0.00037 20.2 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFP10372.1 - 9e-10 38.9 8.4 1.2e-09 38.5 1.0 5.4 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP10372.1 - 1.4e-08 34.5 0.6 3.4e-06 26.8 0.1 4.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP10372.1 - 1.4e-07 30.7 4.5 5e-05 22.6 1.1 3.1 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFP10372.1 - 5.8e-06 26.0 0.4 0.0068 16.2 0.0 3.7 3 0 0 3 3 3 1 CAMSAP CH domain Laminin_II PF06009.12 KFP10372.1 - 0.01 15.8 0.3 0.01 15.8 0.3 31.2 21 7 11 36 36 33 0 Laminin Domain II DUF5304 PF17230.2 KFP10372.1 - 0.36 11.0 16.0 0.52 10.5 0.3 7.6 5 1 1 6 6 6 0 Family of unknown function (DUF5304) RapH_N PF18801.1 KFP10372.1 - 5.6 7.1 8.0 11 6.2 1.5 5.2 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DotA PF11388.8 KFP10372.1 - 8.6 6.6 7.2 1.3e+02 2.8 0.1 5.8 5 0 0 5 5 4 0 Phagosome trafficking protein DotA VWA PF00092.28 KFP10373.1 - 1.1e-42 146.3 0.1 1.7e-42 145.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP10373.1 - 6.6e-15 55.7 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.18 KFP10373.1 - 3.5e-10 39.5 32.6 2.3e-09 36.9 32.6 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) VWA_3 PF13768.6 KFP10373.1 - 0.00024 21.1 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_3 PF13385.6 KFP10373.1 - 0.0005 20.2 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFP10373.1 - 0.089 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain C2 PF00168.30 KFP10374.1 - 1e-41 141.4 0.0 4.8e-15 55.7 0.0 5.5 4 1 0 4 4 4 4 C2 domain Ferlin_C PF16165.5 KFP10374.1 - 3.4e-41 140.7 3.8 7.5e-39 133.1 0.1 4.1 2 2 2 4 4 4 2 Ferlin C-terminus FerB PF08150.12 KFP10374.1 - 1.2e-30 105.9 1.3 2.8e-30 104.8 0.1 2.4 3 0 0 3 3 3 1 FerB (NUC096) domain GP41 PF00517.17 KFP10374.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Synaptobrevin PF00957.21 KFP10374.1 - 1.3 8.9 7.1 2.6 7.9 7.1 1.5 1 0 0 1 1 1 0 Synaptobrevin TMEM65 PF10507.9 KFP10376.1 - 3.6e-47 158.8 2.8 4.2e-47 158.6 2.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 Romo1 PF10247.9 KFP10376.1 - 0.047 14.1 1.9 0.19 12.1 0.0 2.2 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2273 PF10031.9 KFP10376.1 - 8.1 6.6 10.7 0.11 12.5 1.6 2.5 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) TRC8_N PF13705.6 KFP10378.1 - 7.1e-172 572.8 42.1 8.3e-172 572.6 42.1 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 KFP10378.1 - 4.8e-09 36.4 8.6 4.8e-09 36.4 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP10378.1 - 7.6e-09 35.3 7.6 7.6e-09 35.3 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP10378.1 - 1.2e-07 31.9 8.3 4.8e-07 30.0 8.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP10378.1 - 1.7e-06 27.8 8.0 1.7e-06 27.8 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP10378.1 - 7.3e-05 22.6 8.0 7.3e-05 22.6 8.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP10378.1 - 7.8e-05 22.6 5.6 0.001 19.1 5.6 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFP10378.1 - 8.5e-05 22.3 5.4 8.5e-05 22.3 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP10378.1 - 8.8e-05 22.3 4.9 0.00022 21.0 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP10378.1 - 0.0005 19.7 6.1 0.0005 19.7 6.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP10378.1 - 0.0021 18.0 7.9 0.006 16.6 7.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KFP10378.1 - 0.078 13.2 8.5 2.2 8.5 8.5 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 KFP10378.1 - 0.3 11.2 3.1 0.71 10.1 3.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KFP10378.1 - 0.56 9.9 5.4 2.3 7.9 5.4 2.1 1 0 0 1 1 1 0 P-11 zinc finger Zf_RING PF16744.5 KFP10378.1 - 0.77 9.9 6.8 0.3 11.2 3.9 1.8 2 0 0 2 2 1 0 KIAA1045 RING finger FYDLN_acid PF09538.10 KFP10378.1 - 1.8 9.3 5.5 3.4 8.4 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_17 PF17120.5 KFP10378.1 - 2.2 8.0 11.7 0.25 11.0 6.7 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TatD_DNase PF01026.21 KFP10379.1 - 3.2e-50 170.9 0.0 3.8e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 KFP10379.1 - 0.19 11.5 0.0 12 5.6 0.0 2.2 1 1 1 2 2 2 0 Amidohydrolase Complex1_LYR PF05347.15 KFP10380.1 - 3.2e-08 33.5 1.4 6.5e-08 32.5 0.2 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) IMD PF08397.11 KFP10382.1 - 1.2e-79 266.7 5.1 1.6e-79 266.4 5.1 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gp58 PF07902.11 KFP10382.1 - 0.035 12.4 0.8 0.046 12.0 0.8 1.1 1 0 0 1 1 1 0 gp58-like protein CK2S PF15011.6 KFP10382.1 - 0.11 12.4 2.8 0.2 11.5 1.7 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate OmpH PF03938.14 KFP10382.1 - 0.4 11.0 8.6 0.86 9.9 8.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SE PF08491.10 KFP10385.1 - 1.1e-111 372.3 0.0 1.5e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KFP10385.1 - 4.3e-20 72.3 0.0 6.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFP10385.1 - 1.7e-10 41.0 0.1 0.00038 20.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFP10385.1 - 0.00017 22.1 0.1 0.00051 20.5 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP10385.1 - 0.00023 20.4 0.1 0.39 9.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFP10385.1 - 0.00024 21.3 0.1 0.00054 20.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFP10385.1 - 0.0017 17.7 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 KFP10385.1 - 0.0021 18.3 0.1 0.0043 17.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KFP10385.1 - 0.0077 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KFP10385.1 - 0.008 15.6 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase 3HCDH_N PF02737.18 KFP10385.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFP10385.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KFP10385.1 - 0.032 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KFP10385.1 - 0.035 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 KFP10385.1 - 0.047 12.5 0.1 2.9 6.7 0.1 2.6 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_2 PF03446.15 KFP10385.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KFP10385.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFP10385.1 - 0.21 12.2 0.0 0.54 10.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Strumpellin PF10266.9 KFP10386.1 - 0 1664.1 20.7 0 1664.0 20.7 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin HTH_43 PF09904.9 KFP10386.1 - 0.072 13.0 0.1 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix EF-hand_9 PF14658.6 KFP10386.1 - 0.14 12.5 0.0 0.72 10.2 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain DUF3106 PF11304.8 KFP10386.1 - 0.23 12.0 1.2 0.9 10.0 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) FAD_SOX PF18371.1 KFP10386.1 - 0.53 10.7 2.1 11 6.4 0.0 4.1 4 0 0 4 4 4 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF3502 PF12010.8 KFP10386.1 - 1.6 9.4 6.0 14 6.3 0.2 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF3502) zf-Nse PF11789.8 KFP10387.1 - 8.4e-20 70.3 2.0 1.4e-19 69.6 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFP10387.1 - 2.1e-08 34.0 0.1 4.6e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KFP10387.1 - 0.00042 19.8 4.2 0.0017 17.8 4.0 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-MIZ PF02891.20 KFP10387.1 - 0.00078 19.1 1.6 0.0018 18.0 1.6 1.7 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger U-box PF04564.15 KFP10387.1 - 0.0025 17.9 0.1 0.007 16.5 0.1 1.8 1 1 0 1 1 1 1 U-box domain HalX PF08663.10 KFP10387.1 - 0.0032 17.8 2.4 0.058 13.7 0.3 2.5 2 0 0 2 2 2 1 HalX domain zf-C3HC4_2 PF13923.6 KFP10387.1 - 0.0097 15.7 1.7 0.027 14.3 0.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP10387.1 - 0.031 14.6 0.6 0.074 13.4 0.6 1.7 1 0 0 1 1 1 0 Ring finger domain Transferase PF02458.15 KFP10387.1 - 0.046 12.4 0.5 0.063 11.9 0.5 1.1 1 0 0 1 1 1 0 Transferase family zf-C3HC4 PF00097.25 KFP10387.1 - 0.58 10.1 3.1 0.29 11.0 0.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ParB PF08775.10 KFP10387.1 - 0.68 10.4 9.9 3.1 8.3 3.8 2.2 1 1 1 2 2 2 0 ParB family Pkinase PF00069.25 KFP10388.1 - 1.4e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRAT PF04970.13 KFP10392.1 - 4.1e-12 46.5 0.1 1.1e-05 25.7 0.0 2.4 1 1 1 2 2 2 2 Lecithin retinol acyltransferase DUF1394 PF07159.12 KFP10401.1 - 4.1e-142 472.9 0.0 4.7e-142 472.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) V-ATPase_H_N PF03224.14 KFP10401.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H ArfGap PF01412.18 KFP10402.1 - 1e-35 122.3 0.0 3e-35 120.8 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFP10402.1 - 3.7e-25 89.0 12.5 7.4e-25 88.0 12.5 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFP10402.1 - 1.5e-10 41.5 0.4 6.1e-10 39.6 0.4 2.1 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFP10402.1 - 1.1e-09 37.8 0.3 2.2e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 SH3 domain Ank_2 PF12796.7 KFP10402.1 - 1.4e-09 38.4 0.1 5.8e-09 36.4 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_9 PF14604.6 KFP10402.1 - 1.4e-09 37.6 0.2 2.9e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.30 KFP10402.1 - 7.4e-09 35.7 0.3 0.00027 21.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat BAR PF03114.18 KFP10402.1 - 3.3e-08 33.5 6.7 7.1e-08 32.4 6.7 1.5 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 KFP10402.1 - 6.1e-07 29.0 0.2 1.4e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KFP10402.1 - 1.9e-06 28.3 0.8 0.00042 20.8 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP10402.1 - 9.5e-06 25.6 0.4 0.054 14.1 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.6 KFP10402.1 - 0.0028 18.0 0.1 0.041 14.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH_3 PF14593.6 KFP10402.1 - 0.039 14.1 0.1 0.14 12.2 0.1 2.0 2 0 0 2 2 1 0 PH domain PH_9 PF15410.6 KFP10402.1 - 0.12 12.8 1.4 5.8 7.3 0.2 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Guanylate_cyc PF00211.20 KFP10404.1 - 4.1e-88 293.8 0.0 3.7e-58 196.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFP10404.1 - 1.1e-34 120.4 5.4 1.1e-34 120.4 5.4 2.4 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFP10404.1 - 2.6e-28 98.6 0.1 6.8e-28 97.3 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) TBK1_ULD PF18396.1 KFP10404.1 - 0.0062 16.4 0.2 0.016 15.1 0.2 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Phospholip_A2_1 PF00068.19 KFP10409.1 - 6.2e-53 178.0 39.4 9.9e-28 96.9 15.7 2.3 2 0 0 2 2 2 2 Phospholipase A2 DUF717 PF05338.12 KFP10409.1 - 0.019 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF717) KCNQ_channel PF03520.14 KFP10411.1 - 2.9e-82 275.1 0.3 4.6e-82 274.5 0.3 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.8 KFP10411.1 - 1.9e-39 134.1 1.7 1.9e-39 134.1 1.7 1.8 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.31 KFP10411.1 - 1.3e-28 99.8 2.3 1.6e-28 99.6 1.2 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 KFP10411.1 - 7.1e-13 48.3 0.3 1.8e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.26 KFP10411.1 - 0.00036 20.4 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel LRR_9 PF14580.6 KFP10413.1 - 8.2e-15 54.7 1.1 1.8e-14 53.6 1.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP10413.1 - 2.4e-09 37.3 6.8 7.6e-05 23.0 2.9 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP10413.1 - 2.2e-05 24.1 5.7 5.6e-05 22.8 3.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KFP10413.1 - 2.2 9.1 5.3 1.8e+02 3.4 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat TMEM71 PF15121.6 KFP10414.1 - 4.6e-50 169.2 0.3 7.8e-50 168.4 0.3 1.3 1 0 0 1 1 1 1 TMEM71 protein family DUF3149 PF11346.8 KFP10414.1 - 0.3 10.7 2.8 0.19 11.3 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3149) HSBP1 PF06825.12 KFP10415.1 - 0.032 14.1 0.8 0.056 13.3 0.3 1.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 SH2 PF00017.24 KFP10416.1 - 8.5e-21 73.9 0.2 2.1e-20 72.6 0.2 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP10416.1 - 5.6e-07 29.1 0.0 1.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain IGFBP PF00219.18 KFP10417.1 - 1.2e-10 41.8 21.5 1.2e-10 41.8 21.5 5.1 4 3 0 4 4 4 1 Insulin-like growth factor binding protein Cys_knot PF00007.22 KFP10417.1 - 3.5e-09 36.9 8.5 3.5e-09 36.9 8.5 3.7 4 2 0 4 4 4 1 Cystine-knot domain VWC PF00093.18 KFP10417.1 - 1.5e-08 34.8 12.0 1.5e-08 34.8 12.0 5.2 4 3 0 4 4 4 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFP10417.1 - 1.2e-05 25.4 5.9 1.2e-05 25.4 5.9 3.8 4 1 0 4 4 4 1 Thrombospondin type 1 domain Ndr PF03096.14 KFP10418.1 - 1.2e-124 414.6 0.0 1.4e-124 414.4 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFP10418.1 - 0.0016 18.1 0.0 0.084 12.5 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP10418.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-H2C2_5 PF13909.6 KFP10423.1 - 1.1e-05 25.0 0.9 1.1e-05 25.0 0.9 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KFP10423.1 - 1.8e-05 24.9 0.5 1.8e-05 24.9 0.5 5.3 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFP10423.1 - 0.0013 19.0 31.0 0.23 12.0 0.1 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP10423.1 - 0.7 10.9 30.2 0.93 10.5 2.2 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFP10423.1 - 1 9.0 10.3 3.6 7.3 0.2 4.6 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Sulfotransfer_1 PF00685.27 KFP10424.1 - 3.3e-38 131.7 0.2 4.5e-38 131.2 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP10424.1 - 2.1e-14 54.4 1.0 5.5e-09 36.7 0.1 2.6 2 1 1 3 3 3 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP10424.1 - 0.0058 16.6 0.5 0.013 15.5 0.1 1.7 2 0 0 2 2 2 1 Sulfotransferase family AKAP2_C PF15304.6 KFP10424.1 - 0.059 12.7 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Ras PF00071.22 KFP10427.1 - 2.5e-33 115.0 0.0 3.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10427.1 - 2.4e-21 76.1 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP10427.1 - 1.3e-07 31.3 0.1 1.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP10427.1 - 0.005 16.2 0.1 0.0062 15.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FtsZ_C PF12327.8 KFP10427.1 - 0.078 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Prothymosin PF03247.14 KFP10428.1 - 0.032 14.7 9.9 0.032 14.7 9.9 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family LAP1C PF05609.12 KFP10428.1 - 2.9 6.9 19.0 3.2 6.7 19.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RRM_7 PF16367.5 KFP10432.1 - 3e-38 129.8 0.0 2.3e-36 123.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFP10432.1 - 5.1e-21 74.7 5.2 1.2e-20 73.4 5.2 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFP10432.1 - 4.4e-12 45.6 0.0 8.1e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFP10432.1 - 0.079 12.7 0.3 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 U1 zinc finger HSP20 PF00011.21 KFP10432.1 - 0.15 12.2 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-B_box PF00643.24 KFP10432.1 - 0.4 10.9 5.9 0.95 9.7 5.9 1.5 1 0 0 1 1 1 0 B-box zinc finger C1q PF00386.21 KFP10434.1 - 8.5e-39 132.7 0.0 1.1e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP10434.1 - 6.4e-15 54.6 60.5 2.3e-08 33.7 32.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP10434.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 BclA C-terminal domain F-box-like PF12937.7 KFP10435.1 - 4.1e-15 55.4 0.1 1.5e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP10435.1 - 1.1e-10 41.1 0.1 1e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KFP10435.1 - 1.3e-10 41.4 2.5 0.0001 22.6 0.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP10435.1 - 3.2e-10 39.2 4.4 0.0078 16.2 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFP10435.1 - 2.6e-06 27.2 1.3 1.4 9.8 0.0 5.4 4 0 0 4 4 4 2 Leucine Rich Repeat Hemerythrin PF01814.23 KFP10435.1 - 1.1e-05 26.1 5.8 0.00029 21.4 0.5 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LRR_8 PF13855.6 KFP10435.1 - 0.00073 19.3 1.1 0.58 10.0 0.1 3.5 2 1 0 2 2 2 2 Leucine rich repeat F-box_4 PF15966.5 KFP10435.1 - 0.013 15.3 0.1 0.061 13.2 0.0 2.2 2 0 0 2 2 2 0 F-box PRANC PF09372.10 KFP10435.1 - 0.043 14.1 0.1 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 PRANC domain FTCD_C PF04961.12 KFP10435.1 - 0.31 10.8 2.6 2 8.2 1.5 2.3 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase Rib_hydrolayse PF02267.17 KFP10436.1 - 8.9e-17 61.3 0.0 9.6e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Rib_hydrolayse PF02267.17 KFP10437.1 - 4.9e-104 347.0 1.1 5.7e-104 346.8 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase FGF-BP1 PF06473.12 KFP10438.1 - 2.9e-62 210.5 17.1 4.9e-62 209.7 17.1 1.3 1 1 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) FGF-BP1 PF06473.12 KFP10439.1 - 5.7e-53 180.1 0.7 6.7e-53 179.9 0.7 1.0 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Prominin PF05478.11 KFP10440.1 - 2.8e-261 869.0 13.8 3.3e-261 868.8 13.8 1.0 1 0 0 1 1 1 1 Prominin Tweety PF04906.13 KFP10440.1 - 0.0012 17.6 19.9 0.0032 16.2 0.3 3.3 2 1 0 3 3 3 2 Tweety Serine_rich PF08824.10 KFP10440.1 - 0.03 14.3 6.4 0.77 9.7 1.0 3.4 2 1 1 3 3 3 0 Serine rich protein interaction domain DUF1218 PF06749.12 KFP10440.1 - 0.073 13.6 12.8 1.1 9.8 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Fusion_gly PF00523.18 KFP10440.1 - 0.095 10.9 14.0 0.0076 14.6 3.4 2.3 2 0 0 2 2 2 0 Fusion glycoprotein F0 Cyt_bd_oxida_II PF02322.15 KFP10440.1 - 0.11 11.9 4.2 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Prefoldin PF02996.17 KFP10440.1 - 0.28 11.1 3.2 17 5.4 0.1 3.5 3 0 0 3 3 3 0 Prefoldin subunit ATP-synt_I PF03899.15 KFP10440.1 - 0.55 10.6 0.1 0.55 10.6 0.1 3.4 3 1 0 3 3 3 0 ATP synthase I chain ALIX_LYPXL_bnd PF13949.6 KFP10440.1 - 0.57 9.4 3.3 0.41 9.9 0.6 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV COG5 PF10392.9 KFP10440.1 - 3.8 7.7 6.8 2.7 8.2 0.3 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF948 PF06103.11 KFP10440.1 - 3.9 7.8 13.0 13 6.1 0.4 5.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Claudin_2 PF13903.6 KFP10440.1 - 5.5 6.7 10.7 11 5.8 4.6 2.6 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF747 PF05346.11 KFP10441.1 - 8.5e-108 360.6 19.5 1.1e-107 360.2 19.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DASH_Dad4 PF08650.10 KFP10441.1 - 0.039 13.9 3.9 0.25 11.4 2.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 LIM_bind PF01803.16 KFP10442.1 - 2e-55 187.9 10.8 4.5e-44 150.8 0.5 2.8 2 1 1 3 3 3 2 LIM-domain binding protein LID PF17916.1 KFP10442.1 - 1.7e-18 65.9 2.5 3.2e-18 65.1 2.5 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) DTHCT PF08070.11 KFP10442.1 - 0.013 16.2 2.9 0.043 14.6 2.9 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region zf-DNL PF05180.12 KFP10442.1 - 0.085 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 DNL zinc finger Coilin_N PF15862.5 KFP10442.1 - 0.19 11.5 2.5 0.38 10.6 2.5 1.5 1 0 0 1 1 1 0 Coilin N-terminus Vpu PF00558.19 KFP10442.1 - 0.52 10.1 1.6 6.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Vpu protein adh_short_C2 PF13561.6 KFP10443.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Peptidase_M17 PF00883.21 KFP10444.1 - 2.2e-111 372.1 0.0 2.9e-111 371.7 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KFP10444.1 - 2.4e-19 69.4 0.0 5.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Med28 PF11594.8 KFP10445.1 - 9.2e-23 80.8 2.1 3.8e-16 59.4 1.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit 28 Filament PF00038.21 KFP10445.1 - 0.00079 19.1 0.8 0.00084 19.0 0.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein HTH_34 PF13601.6 KFP10445.1 - 0.0051 16.9 0.0 0.0089 16.2 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain HU-CCDC81_bac_2 PF18175.1 KFP10445.1 - 0.0087 15.9 0.3 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 ISG65-75 PF11727.8 KFP10445.1 - 0.1 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Sec2p PF06428.11 KFP10445.1 - 0.12 12.3 3.5 0.16 12.0 3.5 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cnd3 PF12719.7 KFP10446.1 - 2.7e-86 289.4 5.7 3.3e-86 289.1 3.1 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KFP10446.1 - 8.6e-09 35.7 5.6 0.02 15.3 0.4 5.1 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KFP10446.1 - 5.6e-07 29.3 7.4 1.1 9.7 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KFP10446.1 - 0.0022 18.5 10.5 3 8.4 0.3 4.9 4 1 1 5 5 5 3 HEAT-like repeat Cnd1 PF12717.7 KFP10446.1 - 3.4 7.7 20.7 0.39 10.7 0.3 5.2 4 2 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF4553 PF15090.6 KFP10447.1 - 4.1e-157 524.0 31.1 4.1e-157 524.0 31.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) Staphostatin_A PF09022.10 KFP10447.1 - 0.037 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Staphostatin A CagZ PF09053.10 KFP10447.1 - 0.061 12.9 0.1 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 CagZ HTH_psq PF05225.16 KFP10448.1 - 1.4e-24 85.6 0.0 4.8e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain DUF2428 PF10350.9 KFP10448.1 - 0.011 15.1 0.8 0.49 9.6 0.0 2.6 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) LRR_8 PF13855.6 KFP10454.1 - 5e-90 295.2 84.3 1.3e-13 50.5 0.0 10.2 4 4 6 10 10 10 10 Leucine rich repeat LRR_5 PF13306.6 KFP10454.1 - 1.4e-32 112.3 10.2 4.3e-09 36.4 0.1 5.1 6 0 0 6 6 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP10454.1 - 1.4e-31 108.0 63.1 3.3e-05 24.1 0.1 12.1 7 5 8 16 16 16 11 Leucine Rich repeats (2 copies) EGF PF00008.27 KFP10454.1 - 2.4e-28 98.1 89.2 4.1e-08 33.4 7.7 8.0 8 0 0 8 8 7 5 EGF-like domain LRR_9 PF14580.6 KFP10454.1 - 1.3e-21 76.9 17.0 6.3e-07 29.1 0.5 4.6 4 1 0 4 4 4 4 Leucine-rich repeat LRRNT PF01462.18 KFP10454.1 - 1.6e-21 75.5 36.4 1.7e-08 33.9 3.3 7.0 6 0 0 6 6 6 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.23 KFP10454.1 - 3.5e-18 66.1 0.0 6.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.24 KFP10454.1 - 1.9e-17 62.3 8.1 0.0026 18.2 0.1 6.0 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain Laminin_G_2 PF02210.24 KFP10454.1 - 9.5e-16 58.5 0.0 1.9e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFP10454.1 - 6.4e-12 45.6 84.1 1.1e-06 29.0 5.7 9.5 10 1 0 10 10 8 5 Human growth factor-like EGF LRR_1 PF00560.33 KFP10454.1 - 1.7e-05 24.7 44.9 2.6 9.0 0.6 14.3 16 2 0 16 16 15 3 Leucine Rich Repeat FXa_inhibition PF14670.6 KFP10454.1 - 0.0007 19.8 4.2 0.0007 19.8 4.2 7.0 4 2 2 6 6 5 3 Coagulation Factor Xa inhibitory site TPKR_C2 PF16920.5 KFP10454.1 - 3.6 7.8 19.4 7.8 6.7 0.5 6.4 6 0 0 6 6 5 0 Tyrosine-protein kinase receptor C2 Ig-like domain ParcG PF10274.9 KFP10456.1 - 7.2e-48 163.1 0.0 9.2e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein EF-hand_7 PF13499.6 KFP10457.1 - 4.3e-25 87.9 4.4 8.5e-19 67.8 0.3 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP10457.1 - 1.1e-22 77.8 7.3 3.2e-08 32.5 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP10457.1 - 1.3e-18 65.3 9.3 5.5e-06 25.9 0.1 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFP10457.1 - 9.1e-18 62.9 3.7 9.2e-06 24.9 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFP10457.1 - 2.1e-13 49.9 10.2 1.6e-05 24.6 0.5 3.9 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP10457.1 - 3.3e-08 33.8 3.5 1.2e-05 25.5 0.4 3.4 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP10457.1 - 0.00011 22.1 2.2 0.0085 16.0 0.1 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP10457.1 - 0.001 19.3 0.3 6.2 7.2 0.1 3.4 2 1 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KFP10457.1 - 0.0031 17.7 0.2 0.19 11.9 0.0 2.4 1 1 1 2 2 2 2 Dockerin type I domain Erg28 PF03694.13 KFP10457.1 - 0.051 14.0 0.2 0.077 13.4 0.2 1.3 1 0 0 1 1 1 0 Erg28 like protein Caleosin PF05042.13 KFP10457.1 - 0.089 12.7 5.6 13 5.6 0.1 3.2 2 1 1 3 3 3 0 Caleosin related protein S10_plectin PF03501.15 KFP10457.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.11 KFP10457.1 - 0.14 12.3 0.3 14 5.9 0.0 2.6 2 1 0 2 2 2 0 EF hand LRR_8 PF13855.6 KFP10459.1 - 7.7e-16 57.6 13.4 7.4e-11 41.7 5.9 2.6 1 1 1 2 2 2 2 Leucine rich repeat 7tm_2 PF00002.24 KFP10459.1 - 1.4e-12 47.5 8.6 2.6e-12 46.6 8.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP10459.1 - 1.3e-07 32.0 0.0 1.3e-07 32.0 0.0 3.2 4 0 0 4 4 3 1 GPCR proteolysis site, GPS, motif I-set PF07679.16 KFP10459.1 - 2.2e-06 27.7 0.0 5.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KFP10459.1 - 8.6e-05 22.8 14.7 0.0011 19.4 1.7 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) ig PF00047.25 KFP10459.1 - 0.00065 19.8 0.2 0.0022 18.1 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain HRM PF02793.22 KFP10459.1 - 0.0011 19.2 1.0 0.003 17.8 1.0 1.8 1 0 0 1 1 1 1 Hormone receptor domain LRR_5 PF13306.6 KFP10459.1 - 0.0028 17.6 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP10459.1 - 0.0085 16.5 4.1 1.4 9.7 0.3 3.8 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_9 PF14580.6 KFP10459.1 - 0.079 12.5 0.3 0.15 11.6 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeat TPKR_C2 PF16920.5 KFP10459.1 - 0.75 10.0 4.0 1.4 9.1 1.3 2.8 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain RRM_1 PF00076.22 KFP10462.1 - 1.1e-06 28.3 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sod_Cu PF00080.20 KFP10464.1 - 3.9e-31 108.1 0.0 4.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2353 PF09789.9 KFP10465.1 - 3.3e-91 305.9 24.1 3.3e-91 305.9 24.1 1.4 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Baculo_VP39 PF04501.12 KFP10465.1 - 0.01 15.4 0.7 0.017 14.6 0.7 1.3 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 Csm1_N PF18504.1 KFP10465.1 - 0.022 15.1 27.2 0.029 14.7 2.1 5.4 5 0 0 5 5 5 0 Csm1 N-terminal domain Peptidase_M27 PF01742.17 KFP10465.1 - 0.042 13.0 0.2 0.066 12.3 0.2 1.2 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease TSC22 PF01166.18 KFP10465.1 - 0.048 14.0 0.1 0.048 14.0 0.1 5.2 5 0 0 5 5 5 0 TSC-22/dip/bun family CorA PF01544.18 KFP10465.1 - 0.059 12.7 17.1 0.011 15.0 8.3 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CALCOCO1 PF07888.11 KFP10465.1 - 0.062 12.2 22.8 0.02 13.8 19.5 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like THP2 PF09432.10 KFP10465.1 - 0.097 12.7 7.4 0.27 11.3 5.3 2.5 2 0 0 2 2 2 0 Tho complex subunit THP2 DUF4482 PF14818.6 KFP10465.1 - 0.11 13.4 19.7 0.87 10.5 2.1 3.8 3 1 1 4 4 3 0 Domain of unknown function (DUF4482) GAS PF13851.6 KFP10465.1 - 0.17 11.2 30.7 0.03 13.7 5.1 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 KFP10465.1 - 0.39 11.1 13.3 0.074 13.4 7.4 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) LPP PF04728.13 KFP10465.1 - 0.4 11.1 9.7 11 6.5 0.2 4.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Tho2 PF11262.8 KFP10465.1 - 0.45 9.7 5.4 0.51 9.5 3.6 2.0 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 COG2 PF06148.11 KFP10465.1 - 0.49 10.5 9.6 1.4 9.0 0.3 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OEP PF02321.18 KFP10465.1 - 0.5 10.1 11.2 1.4 8.6 11.2 1.8 1 0 0 1 1 1 0 Outer membrane efflux protein LMBR1 PF04791.16 KFP10465.1 - 1.3 7.9 6.6 2.2 7.1 6.6 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin-6_N PF09177.11 KFP10465.1 - 1.3 9.6 13.8 9.6 6.8 0.8 4.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4164 PF13747.6 KFP10465.1 - 1.4 9.3 17.7 1 9.7 5.7 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) DivIVA PF05103.13 KFP10465.1 - 1.4 9.0 21.0 0.21 11.7 5.9 3.4 4 0 0 4 4 4 0 DivIVA protein HAP1_N PF04849.13 KFP10465.1 - 1.4 8.0 28.6 0.068 12.4 12.5 3.7 3 1 1 4 4 4 0 HAP1 N-terminal conserved region Chibby PF14645.6 KFP10465.1 - 2.4 8.6 7.4 5.6 7.4 2.6 3.0 2 1 0 2 2 2 0 Chibby family KLRAQ PF10205.9 KFP10465.1 - 2.7 8.3 20.3 10 6.4 9.2 4.0 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein dCache_2 PF08269.11 KFP10465.1 - 2.9 7.0 6.8 0.3 10.2 1.4 2.0 2 0 0 2 2 2 0 Cache domain FapA PF03961.13 KFP10465.1 - 3.3 6.2 17.8 0.55 8.8 4.5 2.9 1 1 1 3 3 3 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 KFP10465.1 - 6.3 7.3 14.8 28 5.2 0.1 5.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 KFP10465.1 - 8.1 6.4 26.9 0.36 10.7 1.1 4.8 4 1 0 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Sec34 PF04136.15 KFP10465.1 - 9.4 6.1 14.9 0.095 12.6 1.4 3.3 3 1 1 4 4 4 0 Sec34-like family SepSecS PF05889.13 KFP10466.1 - 6.5e-178 591.3 0.0 7.5e-178 591.1 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KFP10466.1 - 1.7e-05 24.3 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KFP10466.1 - 0.068 11.9 0.1 1.2 7.8 0.0 2.2 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain PI3_PI4_kinase PF00454.27 KFP10467.1 - 3.3e-67 226.9 0.0 3.9e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase N6-adenineMlase PF10237.9 KFP10468.1 - 2.6e-20 72.8 0.9 4.4e-20 72.1 0.9 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase zf-GRF PF06839.12 KFP10468.1 - 2.9e-13 49.7 2.6 2.9e-13 49.7 2.6 3.1 2 1 0 2 2 2 1 GRF zinc finger DHHC PF01529.20 KFP10468.1 - 1.2 9.2 28.4 1.7 8.8 14.1 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase Na_Pi_cotrans PF02690.15 KFP10469.1 - 1.4e-39 135.4 23.4 1.9e-24 86.3 6.7 2.6 2 1 0 2 2 2 2 Na+/Pi-cotransporter Sel1 PF08238.12 KFP10470.1 - 1.9e-20 72.8 33.3 9.2e-05 23.0 1.0 8.5 8 0 0 8 8 8 6 Sel1 repeat BTD PF09270.10 KFP10472.1 - 1.4e-75 252.7 0.0 2.2e-75 252.0 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFP10472.1 - 2.4e-50 171.1 0.7 5.9e-50 169.8 0.7 1.7 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 KFP10472.1 - 1.6e-05 24.9 1.2 0.00042 20.4 0.0 2.6 2 0 0 2 2 2 1 IPT/TIG domain RHD_dimer PF16179.5 KFP10472.1 - 0.017 15.1 0.0 0.071 13.1 0.0 2.2 1 1 0 1 1 1 0 Rel homology dimerisation domain DUF4462 PF14692.6 KFP10474.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) LRR_8 PF13855.6 KFP10477.1 - 1e-35 121.3 23.0 1.2e-13 50.5 3.9 4.4 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP10477.1 - 8.9e-23 80.0 25.5 1.9e-05 24.9 3.3 6.2 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP10477.1 - 2e-12 46.9 4.7 0.00019 20.9 3.5 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFP10477.1 - 6.5e-11 42.3 2.3 1.4e-05 25.0 0.4 3.1 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFP10477.1 - 5.8e-10 38.6 10.0 6.7e-10 38.4 5.2 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP10477.1 - 0.00072 19.8 17.7 8.3 7.4 0.1 7.8 8 0 0 8 8 8 2 Leucine Rich Repeat GPS2_interact PF15784.5 KFP10477.1 - 0.095 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain FNIP PF05725.12 KFP10477.1 - 0.38 11.0 6.4 17 5.6 1.9 3.4 2 1 0 2 2 2 0 FNIP Repeat LRR_6 PF13516.6 KFP10477.1 - 0.46 10.7 23.6 2.9 8.2 0.2 7.4 7 1 1 8 8 8 0 Leucine Rich repeat LRR_8 PF13855.6 KFP10478.1 - 1.4e-36 124.1 33.9 4.7e-10 39.1 2.4 6.9 3 1 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP10478.1 - 1.6e-25 88.8 38.1 9.3e-07 29.1 2.9 7.4 2 1 7 9 9 9 9 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFP10478.1 - 4.3e-08 32.6 2.5 4.3e-08 32.6 2.5 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP10478.1 - 4.9e-08 32.7 9.7 0.011 15.2 0.4 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFP10478.1 - 3e-07 30.0 28.6 7.3 7.6 0.0 10.6 8 3 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP10478.1 - 1e-06 28.3 34.8 0.085 13.0 0.1 8.4 10 0 0 10 10 10 5 Leucine Rich repeat LRR_5 PF13306.6 KFP10478.1 - 1.6e-06 28.1 4.3 0.003 17.5 0.1 3.5 2 2 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Rota_NS53 PF00981.17 KFP10478.1 - 0.046 12.6 0.1 0.077 11.9 0.1 1.3 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) LRR_8 PF13855.6 KFP10479.1 - 4.6e-32 109.6 34.0 3e-09 36.5 2.7 6.9 3 2 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP10479.1 - 1.4e-19 69.9 30.6 0.00017 21.9 0.5 7.3 4 3 4 8 8 8 8 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFP10479.1 - 2.2e-06 27.1 4.7 6.4e-06 25.7 2.6 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP10479.1 - 4.3e-06 26.4 13.3 0.0025 17.4 6.4 4.2 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KFP10479.1 - 9.3e-06 25.3 21.9 1.1 9.4 0.3 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_5 PF13306.6 KFP10479.1 - 7.6e-05 22.7 3.0 0.0031 17.5 0.6 3.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) CRT10 PF08728.10 KFP10479.1 - 0.019 13.2 0.0 0.029 12.6 0.0 1.2 1 0 0 1 1 1 0 CRT10 LRR_1 PF00560.33 KFP10479.1 - 0.096 13.3 34.6 4.5 8.2 0.4 10.5 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 KFP10481.1 - 9.6e-23 79.7 8.5 3.8e-12 45.8 0.5 3.7 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP10481.1 - 2.3e-09 37.4 15.4 0.0077 16.6 0.2 4.7 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP10481.1 - 1.8e-07 30.8 6.1 1.8e-05 24.3 1.7 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFP10481.1 - 2.4e-06 27.5 0.2 0.0001 22.3 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP10481.1 - 1.2e-05 25.2 8.8 2.3 9.1 1.5 6.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRRNT PF01462.18 KFP10481.1 - 2.6e-05 23.7 3.3 2.6e-05 23.7 3.3 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP10481.1 - 0.007 16.3 7.2 11 6.3 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich repeat Cation_ATPase_C PF00689.21 KFP10486.1 - 6.8e-45 153.0 3.8 6.8e-45 153.0 3.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFP10486.1 - 3.3e-34 118.0 14.6 7.5e-26 90.8 1.5 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFP10486.1 - 1.2e-28 99.4 3.7 2.9e-14 53.3 1.5 2.8 1 1 1 2 2 2 2 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFP10486.1 - 2e-17 63.1 0.0 4.2e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFP10486.1 - 3.2e-16 58.8 0.0 1.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFP10486.1 - 5.4e-14 53.0 0.2 2.2e-12 47.7 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP10486.1 - 1e-05 25.4 5.4 0.00012 21.9 0.4 2.9 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF2201_N PF13203.6 KFP10486.1 - 0.26 10.9 0.6 0.47 10.0 0.6 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DSPc PF00782.20 KFP10487.1 - 1.4e-43 147.9 0.0 2e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP10487.1 - 0.00022 20.9 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP10487.1 - 0.0085 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFP10487.1 - 0.068 13.3 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate SCF PF02404.15 KFP10488.1 - 3.7e-141 469.3 1.8 4.1e-141 469.1 1.8 1.0 1 0 0 1 1 1 1 Stem cell factor CEP209_CC5 PF16574.5 KFP10489.1 - 7e-51 171.7 24.3 7e-51 171.7 24.3 21.6 12 8 7 20 20 20 3 Coiled-coil region of centrosome protein CE290 Tau95_N PF17682.1 KFP10489.1 - 0.79 9.9 11.8 0.021 15.0 0.9 4.5 2 1 0 2 2 2 0 Tau95 Triple barrel domain DUF5565 PF17720.1 KFP10490.1 - 1.3e-160 533.7 0.2 1.4e-160 533.5 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5565) DUF5571 PF17732.1 KFP10491.1 - 1e-15 58.1 7.2 1.3e-15 57.7 7.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5571) zf-CCCH_3 PF15663.5 KFP10491.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger containing family DUF5571 PF17732.1 KFP10492.1 - 1e-15 58.1 7.2 1.3e-15 57.7 7.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5571) zf-CCCH_3 PF15663.5 KFP10492.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger containing family SMP_C2CD2L PF18696.1 KFP10496.1 - 3.5e-39 134.1 1.3 6.5e-39 133.2 1.3 1.5 1 0 0 1 1 1 1 Synaptotagmin-like, mitochondrial and lipid-binding domain Glycos_transf_4 PF00953.21 KFP10497.1 - 2.4e-36 125.1 16.6 2.4e-36 125.1 16.6 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 Gal_mutarotas_2 PF13802.6 KFP10497.1 - 0.0058 16.9 0.6 0.012 15.9 0.6 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like Porphobil_deam PF01379.20 KFP10498.1 - 5.2e-77 258.0 0.0 6.7e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFP10498.1 - 1.7e-19 70.0 0.1 1.9e-18 66.6 0.0 2.4 1 1 1 2 2 2 1 Porphobilinogen deaminase, C-terminal domain CUE PF02845.16 KFP10498.1 - 0.0042 16.8 0.1 0.44 10.3 0.1 2.6 2 0 0 2 2 2 1 CUE domain MGS PF02142.22 KFP10498.1 - 0.03 14.5 0.0 0.087 13.0 0.0 1.8 2 0 0 2 2 2 0 MGS-like domain VPS11_C PF12451.8 KFP10499.1 - 1.1e-19 70.4 2.4 8.7e-19 67.5 0.4 2.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 KFP10499.1 - 8.9e-18 64.5 12.4 1.4e-15 57.4 2.8 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KFP10499.1 - 2.8e-09 36.7 8.2 6.2e-09 35.6 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP10499.1 - 3.2e-08 33.8 8.8 8e-08 32.5 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP10499.1 - 3.5e-05 24.0 6.7 0.00011 22.5 6.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP10499.1 - 0.00014 21.7 8.0 0.0003 20.6 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFP10499.1 - 0.00096 19.1 9.4 0.0024 17.9 9.4 1.7 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 KFP10499.1 - 0.0024 17.8 8.3 0.0061 16.5 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP10499.1 - 0.0086 16.1 9.5 0.026 14.5 9.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP10499.1 - 0.012 15.4 5.2 0.025 14.4 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Paralemmin PF03285.15 KFP10499.1 - 0.033 13.8 0.9 0.058 13.0 0.9 1.4 1 0 0 1 1 1 0 Paralemmin zf-ANAPC11 PF12861.7 KFP10499.1 - 0.04 14.0 2.0 0.14 12.2 2.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DLP_helical PF18709.1 KFP10499.1 - 0.15 11.2 2.6 0.36 10.0 2.6 1.6 1 0 0 1 1 1 0 Dynamin-like helical domain DivIC PF04977.15 KFP10499.1 - 0.16 11.8 4.4 0.51 10.1 4.4 1.9 1 0 0 1 1 1 0 Septum formation initiator zf-C3HC4_4 PF15227.6 KFP10499.1 - 0.16 12.2 9.0 0.43 10.8 9.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KFP10499.1 - 0.21 11.9 7.2 0.69 10.3 7.2 2.0 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 KFP10499.1 - 0.24 11.2 8.5 0.71 9.7 8.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger TPR_11 PF13414.6 KFP10499.1 - 0.29 10.8 4.4 1.6 8.5 0.0 4.0 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 KFP10499.1 - 0.57 10.4 3.2 19 5.7 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 KFP10499.1 - 2.9 7.9 12.0 15 5.6 4.9 3.8 3 0 0 3 3 3 0 Prefoldin subunit Zn_ribbon_17 PF17120.5 KFP10499.1 - 6.3 6.5 10.5 2.1 8.0 6.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DEAD PF00270.29 KFP10500.1 - 1.4e-41 142.2 1.9 2.5e-41 141.4 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP10500.1 - 2.4e-28 98.7 0.7 3.5e-27 94.9 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFP10500.1 - 0.00072 19.0 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFP10500.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ras PF00071.22 KFP10502.1 - 1.6e-59 200.2 0.2 1.8e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10502.1 - 2e-33 115.2 0.1 2.9e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP10502.1 - 4.1e-14 52.4 0.1 4.6e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP10502.1 - 5.9e-06 25.8 0.1 7.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP10502.1 - 0.0002 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP10502.1 - 0.00031 20.7 0.7 0.49 10.3 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP10502.1 - 0.00072 19.1 0.3 0.0017 17.9 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP10502.1 - 0.00082 18.9 0.1 0.0037 16.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFP10502.1 - 0.0052 16.2 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFP10502.1 - 0.014 15.8 0.1 0.029 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AsnC_trans_reg2 PF17805.1 KFP10502.1 - 0.019 15.1 0.2 0.066 13.4 0.1 1.8 2 0 0 2 2 2 0 AsnC-like ligand binding domain Septin PF00735.18 KFP10502.1 - 0.023 14.0 0.2 0.06 12.6 0.2 1.7 1 1 0 1 1 1 0 Septin AAA_22 PF13401.6 KFP10502.1 - 0.049 13.9 0.1 0.18 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFP10502.1 - 0.07 13.6 0.1 0.94 9.9 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFP10502.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFP10502.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.32 KFP10503.1 - 1.2e-31 108.3 21.8 4.6e-08 33.6 1.2 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KFP10503.1 - 3.2e-08 33.3 1.3 6e-08 32.4 1.3 1.4 1 0 0 1 1 1 1 WD40-like domain zf-RING_UBOX PF13445.6 KFP10503.1 - 1.4e-06 28.2 8.4 9.3e-06 25.6 8.4 2.5 1 0 0 1 1 1 1 RING-type zinc-finger Sina PF03145.16 KFP10503.1 - 9.5e-06 25.7 10.0 0.0026 17.7 0.5 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.18 KFP10503.1 - 2.8e-05 24.7 6.0 2.8e-05 24.7 6.0 2.5 2 1 0 2 2 1 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KFP10503.1 - 4.3e-05 23.3 14.3 4.3e-05 23.3 14.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP10503.1 - 4.6e-05 23.2 10.3 4.6e-05 23.2 10.3 3.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP10503.1 - 0.00023 21.2 7.3 0.00023 21.2 7.3 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING PKcGMP_CC PF16808.5 KFP10503.1 - 0.00039 20.2 0.7 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C3HC4_3 PF13920.6 KFP10503.1 - 0.00058 19.7 11.4 0.00058 19.7 11.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.8 KFP10503.1 - 0.00061 18.6 6.7 0.0028 16.4 0.5 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 zf-RING_5 PF14634.6 KFP10503.1 - 0.0087 16.0 13.3 0.0087 16.0 13.3 3.2 3 0 0 3 3 2 1 zinc-RING finger domain DUF16 PF01519.16 KFP10503.1 - 0.013 16.0 0.1 0.027 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Nucleoporin_N PF08801.11 KFP10503.1 - 0.014 14.2 0.9 0.97 8.1 0.0 3.3 1 1 1 3 3 3 0 Nup133 N terminal like KxDL PF10241.9 KFP10503.1 - 0.08 13.2 1.3 0.17 12.2 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein PQQ_3 PF13570.6 KFP10503.1 - 0.08 13.5 2.4 21 5.8 0.1 4.8 5 1 0 5 5 4 0 PQQ-like domain DUF641 PF04859.12 KFP10503.1 - 0.088 13.1 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.10 KFP10503.1 - 0.2 12.0 0.2 0.33 11.3 0.2 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KFP10503.1 - 0.21 12.2 0.4 0.54 10.9 0.4 1.6 1 0 0 1 1 1 0 SlyX HSBP1 PF06825.12 KFP10503.1 - 1.1 9.2 4.7 7.7 6.5 4.7 2.1 1 1 0 1 1 1 0 Heat shock factor binding protein 1 zf-Nse PF11789.8 KFP10503.1 - 2.8 7.8 11.8 2.3 8.1 7.3 2.7 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KFP10503.1 - 8.5 6.8 20.4 0.71 10.2 13.3 3.0 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.32 KFP10505.1 - 1.9e-23 82.2 4.7 2.2e-05 25.1 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10505.1 - 1.5e-09 38.1 0.2 0.0003 21.0 0.1 3.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KFP10505.1 - 0.00085 19.1 0.4 0.078 12.7 0.0 2.6 1 1 2 3 3 3 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KFP10505.1 - 0.0017 17.4 0.1 0.72 8.8 0.0 3.1 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP10505.1 - 0.023 13.3 1.2 5.8 5.4 0.0 3.2 1 1 3 4 4 4 0 Nucleoporin Nup120/160 DUF2415 PF10313.9 KFP10505.1 - 0.062 13.2 0.4 4 7.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Frtz PF11768.8 KFP10505.1 - 0.17 10.2 0.1 0.2 9.9 0.1 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz BRICHOS PF04089.14 KFP10506.1 - 2.6e-19 69.3 0.1 4.3e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 BRICHOS domain PriCT_1 PF08708.11 KFP10506.1 - 0.031 14.0 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) DHHC PF01529.20 KFP10507.1 - 1.9e-32 112.1 14.4 1.9e-32 112.1 14.4 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 KFP10507.1 - 0.41 11.3 5.4 0.77 10.5 5.4 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein OppC_N PF12911.7 KFP10507.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.5 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C FH2 PF02181.23 KFP10508.1 - 1.1e-90 304.4 9.5 1.5e-90 304.0 9.5 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ PF00595.24 KFP10508.1 - 2.9e-13 50.0 0.0 5.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP10508.1 - 5.3e-08 32.6 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP10508.1 - 0.00084 19.6 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RMI1_N PF08585.12 KFP10508.1 - 0.73 9.6 3.1 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 RecQ mediated genome instability protein SSF PF00474.17 KFP10509.1 - 5.6e-146 486.6 20.2 7.9e-146 486.1 20.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family BLUF PF04940.12 KFP10510.1 - 0.0019 18.3 0.0 0.027 14.6 0.0 2.3 2 1 0 2 2 2 1 Sensors of blue-light using FAD BAR PF03114.18 KFP10511.1 - 2.1e-52 178.1 7.0 2.1e-52 178.1 7.0 1.6 2 0 0 2 2 2 1 BAR domain RhoGAP PF00620.27 KFP10511.1 - 4.3e-45 153.2 0.1 3e-44 150.5 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain BAR_2 PF10455.9 KFP10511.1 - 0.00036 19.8 2.1 0.00076 18.7 2.1 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP10511.1 - 0.01 15.6 0.9 0.01 15.6 0.9 1.8 2 1 0 2 2 2 0 BAR domain of APPL family APP_E2 PF12925.7 KFP10511.1 - 0.29 10.8 3.0 8.4 6.1 0.4 3.1 2 1 1 3 3 3 0 E2 domain of amyloid precursor protein LCM PF04072.14 KFP10512.1 - 1.8e-37 129.2 0.0 3.5e-37 128.2 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MIP PF00230.20 KFP10513.1 - 0.00035 20.4 0.0 0.00041 20.1 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 KFP10514.1 - 1.1e-61 208.6 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10514.1 - 5e-38 130.9 0.0 7.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFP10514.1 - 1.1e-26 93.1 0.1 1.8e-26 92.4 0.1 1.3 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KFP10514.1 - 2.7e-19 68.8 17.0 1.4e-17 63.3 5.8 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFP10514.1 - 0.00015 22.4 1.5 0.00035 21.2 1.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP10514.1 - 0.007 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP10514.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CEP76-C2 PF15627.6 KFP10514.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain APH PF01636.23 KFP10514.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PMP22_Claudin PF00822.20 KFP10515.1 - 4.2e-34 117.8 0.4 5.9e-34 117.3 0.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP10515.1 - 4.1e-09 36.5 0.5 7.8e-09 35.6 0.6 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction zf-CCHC_2 PF13696.6 KFP10516.1 - 2.5e-09 36.8 6.8 2.5e-09 36.8 6.8 1.8 2 0 0 2 2 1 1 Zinc knuckle U-box PF04564.15 KFP10516.1 - 3.2e-07 30.4 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 KFP10516.1 - 1.4e-05 24.8 11.3 1.4e-05 24.8 11.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KFP10516.1 - 2.3e-05 24.3 2.7 4.6e-05 23.3 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DWNN PF08783.11 KFP10516.1 - 3e-05 24.2 3.4 5.2e-05 23.4 0.2 2.8 2 0 0 2 2 2 1 DWNN domain zf-C3HC4_3 PF13920.6 KFP10516.1 - 4.3e-05 23.3 9.7 4.3e-05 23.3 9.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP10516.1 - 0.0013 18.6 11.0 0.0032 17.4 11.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP10516.1 - 0.0028 17.9 11.7 0.0054 17.1 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP10516.1 - 0.014 15.5 11.9 0.039 14.1 11.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFP10516.1 - 0.016 15.0 12.2 0.034 14.0 12.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP10516.1 - 0.18 11.9 10.2 0.43 10.7 10.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFP10516.1 - 0.37 10.7 4.5 0.75 9.7 4.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFP10516.1 - 0.41 10.5 10.2 0.87 9.5 10.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFP10516.1 - 2.3 8.3 9.2 2.4 8.2 4.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon TNRC6-PABC_bdg PF16608.5 KFP10517.1 - 1.5e-121 405.7 33.6 1.5e-121 405.7 33.6 7.6 6 2 0 6 6 6 1 TNRC6-PABC binding domain Ago_hook PF10427.9 KFP10517.1 - 3.1e-15 57.1 16.5 3.1e-15 57.1 16.5 11.0 3 2 4 7 7 7 1 Argonaute hook RRM_1 PF00076.22 KFP10517.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP-binding PF00550.25 KFP10518.1 - 8e-13 48.5 0.1 8.4e-13 48.5 0.1 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFP10518.1 - 0.00062 19.9 0.1 0.00062 19.9 0.1 1.0 1 0 0 1 1 1 1 Acyl-carrier PALB2_WD40 PF16756.5 KFP10519.1 - 1.4e-176 586.6 0.4 1.8e-176 586.2 0.4 1.1 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Hexapep PF00132.24 KFP10520.1 - 6.7e-16 57.3 22.7 4.7e-06 26.1 2.9 4.3 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFP10520.1 - 0.00013 21.6 9.5 0.0042 16.8 0.5 3.9 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFP10520.1 - 0.0077 14.4 0.3 0.0092 14.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFP10520.1 - 0.038 12.9 1.7 0.083 11.8 1.3 1.7 1 1 1 2 2 2 0 L-fucokinase Pkinase PF00069.25 KFP10521.1 - 3.7e-40 137.9 0.0 7.4e-40 137.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KFP10521.1 - 2.1e-36 124.9 0.0 3.7e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KFP10521.1 - 4.5e-23 81.8 0.0 1.1e-22 80.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PQQ_2 PF13360.6 KFP10521.1 - 7.5e-08 32.2 0.0 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFP10521.1 - 9.5e-08 31.6 3.0 0.0035 17.2 0.0 3.5 4 0 0 4 4 4 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 KFP10521.1 - 0.00069 18.5 0.0 0.0027 16.6 0.0 1.7 1 1 0 2 2 2 1 Fungal protein kinase PQQ_3 PF13570.6 KFP10521.1 - 0.0011 19.3 0.5 19 5.9 0.0 5.6 5 0 0 5 5 5 0 PQQ-like domain APH PF01636.23 KFP10521.1 - 0.0025 17.8 0.5 0.11 12.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP10521.1 - 0.0047 16.3 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAP_PilO PF06864.12 KFP10521.1 - 0.056 12.3 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF4381 PF14316.6 KFP10521.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ubiquitin PF00240.23 KFP10522.1 - 3.4e-13 49.1 0.0 7.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KFP10522.1 - 0.00052 20.4 0.1 0.0039 17.6 0.0 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KFP10522.1 - 0.0033 17.7 0.1 0.007 16.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain tRNA-synt_1c PF00749.21 KFP10523.1 - 2.7e-80 269.6 0.0 3.8e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Pox_A6 PF04924.12 KFP10523.1 - 0.15 11.0 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein VHS PF00790.19 KFP10524.1 - 1.6e-44 151.2 2.8 1e-43 148.5 0.0 2.6 3 0 0 3 3 3 1 VHS domain GGA_N-GAT PF18308.1 KFP10524.1 - 1.3e-18 66.4 4.3 1.3e-18 66.4 4.3 2.3 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 KFP10524.1 - 1e-16 61.0 3.1 1e-16 61.0 3.1 2.6 1 1 1 2 2 2 1 GAT domain DUF2959 PF11172.8 KFP10524.1 - 0.0056 16.8 3.7 0.0099 16.0 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) PCRF PF03462.18 KFP10524.1 - 0.068 13.0 4.7 0.14 12.0 4.7 1.6 1 0 0 1 1 1 0 PCRF domain SRP_SPB PF02978.19 KFP10524.1 - 0.07 13.8 0.8 0.16 12.6 0.8 1.5 1 0 0 1 1 1 0 Signal peptide binding domain DUF924 PF06041.11 KFP10524.1 - 0.081 13.0 0.5 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Cytochrom_C_2 PF01322.20 KFP10524.1 - 0.1 13.5 0.1 0.36 11.7 0.0 2.0 2 1 0 2 2 2 0 Cytochrome C' DUF4874 PF16173.5 KFP10524.1 - 0.15 11.7 0.8 0.31 10.7 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Flagellin_N PF00669.20 KFP10524.1 - 0.16 12.1 3.3 0.22 11.6 2.9 1.5 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF3837 PF12939.7 KFP10524.1 - 0.24 11.8 2.4 0.66 10.4 1.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3837) CR6_interact PF10147.9 KFP10524.1 - 0.66 9.7 7.5 0.9 9.2 6.8 1.5 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DASH_Dad4 PF08650.10 KFP10524.1 - 0.71 9.9 3.7 3.6 7.6 3.1 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad4 COG7 PF10191.9 KFP10525.1 - 5.6e-302 1003.7 17.1 6.3e-302 1003.5 17.1 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) ICE2 PF08426.10 KFP10525.1 - 0.065 12.3 0.4 0.12 11.5 0.4 1.3 1 0 0 1 1 1 0 ICE2 FlgN PF05130.12 KFP10525.1 - 0.68 10.4 10.2 7.3 7.1 4.4 3.0 2 1 0 2 2 2 0 FlgN protein ASC PF00858.24 KFP10526.1 - 4.5e-113 378.5 5.2 5.5e-113 378.2 5.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Toxin_TOLIP PF00087.21 KFP10526.1 - 0.0018 18.5 1.8 0.0054 17.0 1.8 1.7 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UCH PF00443.29 KFP10527.1 - 1e-39 136.6 0.0 3.1e-39 135.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP10527.1 - 7.4e-11 42.2 0.2 1.1e-05 25.2 0.1 3.1 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_10 PF10058.9 KFP10527.1 - 0.024 14.3 0.4 13 5.6 0.0 2.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 KFP10527.1 - 0.25 11.4 3.2 9.8 6.2 0.0 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-MIZ PF02891.20 KFP10527.1 - 3.5 7.4 9.3 1.5 8.6 5.2 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Sulfotransfer_1 PF00685.27 KFP10528.1 - 3.2e-35 121.9 0.0 3.6e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP10528.1 - 1.4e-11 45.2 0.0 2.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP10528.1 - 0.011 15.7 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase family Peptidase_M13_N PF05649.13 KFP10530.1 - 1.3e-116 390.4 5.4 1.3e-116 390.4 5.4 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP10530.1 - 3.3e-72 242.4 1.3 3.6e-72 242.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.18 KFP10530.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M48 Pox_I5 PF04713.12 KFP10530.1 - 0.062 13.4 0.7 0.13 12.3 0.7 1.4 1 0 0 1 1 1 0 Poxvirus protein I5 HLH PF00010.26 KFP10531.1 - 1.2e-15 57.2 3.2 1.9e-15 56.5 3.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP10531.1 - 3.5e-07 30.3 0.5 6.6e-07 29.4 0.5 1.4 1 0 0 1 1 1 1 Hairy Orange RL10P_insert PF17777.1 KFP10531.1 - 0.17 11.9 0.4 0.68 10.0 0.1 2.0 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P HLH PF00010.26 KFP10532.1 - 3.5e-15 55.7 2.1 6.2e-15 54.9 2.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP10532.1 - 0.0002 21.5 0.1 0.00033 20.8 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFP10533.1 - 8.1e-16 57.7 3.4 1.3e-15 57.0 3.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP10533.1 - 1.2e-09 38.2 0.5 1.8e-09 37.7 0.5 1.3 1 0 0 1 1 1 1 Hairy Orange Fumble PF03630.14 KFP10534.1 - 1.9e-128 428.3 3.3 2.4e-128 428.0 3.3 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KFP10534.1 - 1.7e-56 191.7 0.0 2.7e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 vATP-synt_E PF01991.18 KFP10534.1 - 0.033 13.6 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Lig_chan PF00060.26 KFP10535.1 - 8.1e-40 136.1 0.5 1.2e-39 135.5 0.5 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP10535.1 - 7.2e-37 126.1 0.0 1.3e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP10535.1 - 1.7e-20 73.4 0.0 2.4e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Borrelia_orfA PF02414.15 KFP10535.1 - 0.0048 16.6 0.1 0.0072 16.0 0.1 1.1 1 0 0 1 1 1 1 Borrelia ORF-A Pex2_Pex12 PF04757.14 KFP10536.1 - 3e-34 118.6 2.1 3.8e-34 118.3 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KFP10536.1 - 1.6e-09 37.9 15.8 3.6e-09 36.8 15.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP10536.1 - 2.7e-09 36.7 12.4 5e-09 35.9 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP10536.1 - 9.1e-08 31.8 11.1 9.1e-08 31.8 11.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP10536.1 - 3.4e-07 30.0 14.0 7.5e-07 28.9 14.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP10536.1 - 6.3e-07 29.1 13.5 1.3e-06 28.2 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP10536.1 - 1.7e-05 25.0 11.3 4.7e-05 23.6 11.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP10536.1 - 4.4e-05 23.4 13.3 9.9e-05 22.3 7.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP10536.1 - 8.2e-05 22.5 13.2 0.00018 21.4 13.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF3290 PF11694.8 KFP10536.1 - 0.0034 17.4 0.2 0.0071 16.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) zf-C3HC4_4 PF15227.6 KFP10536.1 - 0.01 16.0 11.7 0.037 14.2 11.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFP10536.1 - 0.019 14.8 3.6 0.036 13.9 3.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KFP10536.1 - 0.03 14.1 4.2 0.49 10.2 3.0 2.7 2 1 0 2 2 2 0 RING-like zinc finger SLATT_3 PF18184.1 KFP10536.1 - 0.12 12.6 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 zf-RING_4 PF14570.6 KFP10536.1 - 0.13 12.1 10.5 0.27 11.0 10.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TMCCDC2 PF15844.5 KFP10536.1 - 0.17 11.8 1.3 0.8 9.6 0.1 2.4 3 0 0 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 zf-ANAPC11 PF12861.7 KFP10536.1 - 0.19 11.8 6.7 0.38 10.8 6.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rer1 PF03248.13 KFP10537.1 - 7.2e-78 260.2 8.2 8.2e-78 260.0 8.2 1.0 1 0 0 1 1 1 1 Rer1 family Bestrophin PF01062.21 KFP10537.1 - 0.013 14.9 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF2208 PF09973.9 KFP10537.1 - 0.84 9.2 8.4 0.14 11.8 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pkinase PF00069.25 KFP10539.1 - 4e-64 216.5 0.0 5.2e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10539.1 - 2.4e-33 115.5 0.0 3.8e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP10539.1 - 1.2e-14 54.0 6.7 2.4e-14 53.0 6.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 KFP10539.1 - 2.7e-11 43.2 0.2 6.8e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.24 KFP10539.1 - 9.6e-06 26.2 1.6 2.4e-05 24.9 1.6 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP10539.1 - 3.3e-05 23.4 0.0 5.9e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP10539.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFP10539.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KFP10539.1 - 0.033 14.5 2.5 0.075 13.4 2.5 1.6 1 0 0 1 1 1 0 C1 domain FTA2 PF13095.6 KFP10539.1 - 0.036 13.7 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP10539.1 - 0.049 13.5 0.1 0.23 11.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DZR PF12773.7 KFP10539.1 - 4.3 7.4 5.5 1.1 9.3 2.2 1.8 2 0 0 2 2 1 0 Double zinc ribbon Neur_chan_LBD PF02931.23 KFP10540.1 - 1.2e-48 165.5 0.1 2e-48 164.7 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP10540.1 - 2.6e-33 116.1 6.3 4.2e-30 105.6 2.4 2.3 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PapD-like PF14874.6 KFP10541.1 - 1.6e-05 25.0 0.0 0.065 13.4 0.0 2.6 2 0 0 2 2 2 2 Flagellar-associated PapD-like ASH PF15780.5 KFP10541.1 - 4.1e-05 23.7 0.0 0.32 11.2 0.0 3.4 3 1 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP10541.1 - 0.0033 17.6 0.0 4.2 7.7 0.0 3.5 3 0 0 3 3 3 1 Transmembrane protein 131-like TMEM52 PF14979.6 KFP10542.1 - 1.2e-29 103.1 1.5 1.3e-29 103.0 1.5 1.0 1 0 0 1 1 1 1 Transmembrane 52 NAD_kinase PF01513.21 KFP10543.1 - 2.8e-66 223.7 0.1 3.4e-66 223.4 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFP10543.1 - 0.046 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TPT PF03151.16 KFP10545.1 - 4.9e-92 308.4 24.0 5.7e-92 308.1 24.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP10545.1 - 4.6e-12 46.3 29.3 6.5e-06 26.4 12.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFP10545.1 - 3.6e-08 33.0 24.9 4.8e-08 32.6 24.9 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFP10545.1 - 0.00065 19.0 9.2 0.00065 19.0 9.2 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF4407 PF14362.6 KFP10547.1 - 1.7 7.9 17.2 2.3 7.5 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JIP_LZII PF16471.5 KFP10547.1 - 3.1 8.0 18.5 0.076 13.2 2.7 3.6 2 2 1 3 3 3 0 JNK-interacting protein leucine zipper II ERG4_ERG24 PF01222.17 KFP10549.1 - 8.5e-66 222.5 0.7 1.1e-65 222.1 0.7 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor PF09465.10 KFP10549.1 - 3.3e-30 103.7 0.4 6.1e-30 102.8 0.4 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Corona_nucleoca PF00937.18 KFP10549.1 - 0.007 15.4 3.0 0.01 14.9 3.0 1.1 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein DUF1325 PF07039.11 KFP10549.1 - 0.05 13.7 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 SGF29 tudor-like domain DUF2207 PF09972.9 KFP10549.1 - 0.091 11.5 0.4 0.18 10.6 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tudor_3 PF18115.1 KFP10549.1 - 0.095 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 KFP10549.1 - 0.15 11.8 0.9 0.39 10.4 0.6 1.9 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain DUF515 PF04415.12 KFP10549.1 - 1.9 6.8 4.5 3.1 6.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) WH1 PF00568.23 KFP10551.1 - 7e-40 135.4 0.2 1e-39 134.9 0.2 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 KFP10551.1 - 4.9e-13 48.4 0.3 1.2e-12 47.1 0.3 1.7 1 0 0 1 1 1 1 VASP tetramerisation domain SRP9-21 PF05486.12 KFP10552.1 - 1.3e-06 28.7 0.1 2.1e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) EHN PF06441.12 KFP10553.1 - 7.3e-32 110.0 0.3 1.3e-31 109.2 0.3 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFP10553.1 - 1.2e-19 71.0 0.0 2.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP10553.1 - 0.0002 22.0 0.2 0.15 12.6 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family RSN1_7TM PF02714.15 KFP10554.1 - 6.5e-59 199.5 27.6 6.5e-59 199.5 27.6 3.2 2 1 1 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFP10554.1 - 5.2e-45 153.8 0.6 8.3e-45 153.2 0.6 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFP10554.1 - 3.6e-22 78.8 0.5 3.6e-22 78.8 0.5 5.0 5 1 0 6 6 6 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KFP10554.1 - 0.0074 16.1 0.0 0.49 10.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGFb_propeptide PF00688.18 KFP10555.1 - 1e-18 68.0 0.9 2.3e-17 63.6 0.2 2.0 2 0 0 2 2 2 2 TGF-beta propeptide Sde2_N_Ubi PF13019.6 KFP10556.1 - 8.9e-24 84.2 1.0 1.1e-23 83.8 1.0 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Tmemb_cc2 PF10267.9 KFP10556.1 - 0.015 14.4 1.6 0.02 14.0 1.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Exonuc_VII_L PF02601.15 KFP10556.1 - 0.021 14.4 1.3 0.024 14.2 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ARGLU PF15346.6 KFP10556.1 - 0.05 13.5 8.2 0.07 13.0 8.2 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Histone PF00125.24 KFP10557.1 - 1.2e-43 148.6 0.4 1.3e-43 148.5 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP10557.1 - 4.4e-05 23.5 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFP10557.1 - 0.00012 22.4 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP10557.1 - 0.028 14.7 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP10557.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GOLD_2 PF13897.6 KFP10558.1 - 6.9e-72 240.4 4.4 6.9e-72 240.4 4.4 3.1 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 KFP10558.1 - 1.2e-13 51.1 0.0 4.4e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Acyl CoA binding protein Merozoite_SPAM PF07133.11 KFP10558.1 - 1.4 8.9 30.9 0.45 10.5 18.2 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) FTCD_C PF04961.12 KFP10558.1 - 9.7 5.9 11.6 6.3 6.5 0.7 2.8 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase DIRP PF06584.13 KFP10559.1 - 2.5e-47 159.4 0.3 7.3e-47 157.9 0.3 1.8 1 0 0 1 1 1 1 DIRP DUF2664 PF10867.8 KFP10559.1 - 0.017 15.5 0.3 0.054 14.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) FTA4 PF13093.6 KFP10559.1 - 0.026 14.4 4.1 0.043 13.7 2.4 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Med30 PF11315.8 KFP10559.1 - 0.33 11.1 4.6 0.17 12.1 1.6 2.1 2 1 0 2 2 2 0 Mediator complex subunit 30 zf-PARP PF00645.18 KFP10560.1 - 3.4e-13 50.3 7.3 6.4e-07 30.1 0.1 2.2 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region IPK PF03770.16 KFP10564.1 - 8.3e-45 153.1 0.0 1.8e-44 152.0 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Retrotrans_gag PF03732.17 KFP10564.1 - 0.016 15.4 1.1 0.51 10.7 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein Presenilin PF01080.17 KFP10565.1 - 1.1e-158 528.2 16.8 8.4e-112 373.8 12.6 2.6 2 1 1 3 3 3 2 Presenilin DUF4643 PF15485.6 KFP10565.1 - 0.031 14.1 1.5 0.055 13.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) ABC1 PF03109.16 KFP10566.1 - 1.2e-33 115.8 0.0 2.2e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family DUF2959 PF11172.8 KFP10566.1 - 0.043 14.0 0.2 0.28 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) CNH PF00780.22 KFP10567.1 - 1.1e-77 261.3 0.1 2.2e-77 260.4 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP10567.1 - 3.1e-55 187.4 0.0 1.2e-54 185.5 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain KELK PF15796.5 KFP10567.1 - 1.3e-32 112.1 20.6 1.3e-32 112.1 20.6 7.5 5 3 2 7 7 6 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFP10567.1 - 3.2e-29 102.0 0.0 9.7e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.10 KFP10567.1 - 2.1e-25 88.6 11.2 2.1e-25 88.6 11.2 9.3 7 4 2 10 10 9 2 DMPK coiled coil domain like C1_1 PF00130.22 KFP10567.1 - 2.2e-11 43.5 8.1 2.2e-11 43.5 8.1 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP10567.1 - 4.8e-07 29.4 0.0 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KFP10567.1 - 7.1e-05 23.4 3.3 9.3e-05 23.0 1.6 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain PBD PF00786.28 KFP10567.1 - 0.011 16.1 0.1 0.075 13.4 0.0 2.6 2 0 0 2 2 2 0 P21-Rho-binding domain Seadorna_VP7 PF07387.11 KFP10567.1 - 0.059 12.4 0.3 0.16 11.0 0.3 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 Calici_MSP PF05752.11 KFP10567.1 - 0.95 9.3 5.1 3.6 7.4 4.6 2.3 1 1 0 1 1 1 0 Calicivirus minor structural protein Ald_Xan_dh_C2 PF02738.18 KFP10569.1 - 9.4e-206 684.5 0.0 1.4e-205 684.0 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFP10569.1 - 1.8e-53 180.7 0.0 3.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KFP10569.1 - 2.3e-37 127.7 0.3 4.2e-37 126.9 0.3 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KFP10569.1 - 4e-33 113.6 0.0 1.1e-32 112.3 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KFP10569.1 - 1.4e-29 101.9 0.1 3.3e-29 100.7 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KFP10569.1 - 7.3e-09 35.5 3.4 8.4e-09 35.3 0.4 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KFP10569.1 - 0.09 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 DUF218 domain DUF5600 PF18150.1 KFP10570.1 - 3.1e-44 149.9 1.8 3.1e-44 149.9 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFP10570.1 - 3.5e-19 68.7 0.2 1.8e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 KFP10570.1 - 2.4e-18 65.7 4.5 5.5e-18 64.6 4.5 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KFP10570.1 - 8.9e-13 48.6 0.0 5.6e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFP10570.1 - 3.5e-09 36.7 0.0 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFP10570.1 - 0.00065 19.1 0.8 0.0025 17.2 0.2 2.4 2 0 0 2 2 1 1 EF hand GTP_EFTU PF00009.27 KFP10570.1 - 0.006 16.1 0.1 0.088 12.3 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFP10570.1 - 0.0079 16.4 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP10570.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AIG1 PF04548.16 KFP10570.1 - 0.014 14.7 0.0 0.081 12.2 0.0 2.2 3 0 0 3 3 3 0 AIG1 family AAA_28 PF13521.6 KFP10570.1 - 0.035 14.3 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 KFP10570.1 - 0.047 14.1 0.2 0.31 11.4 0.0 2.4 2 2 0 2 2 2 0 AAA ATPase domain EF-hand_7 PF13499.6 KFP10570.1 - 0.1 13.1 0.1 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair cobW PF02492.19 KFP10570.1 - 0.14 11.8 0.0 20 4.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KFP10570.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_8 PF13833.6 KFP10570.1 - 0.38 10.6 2.0 0.84 9.5 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain pair Glycos_transf_2 PF00535.26 KFP10571.1 - 9.2e-23 80.9 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP10571.1 - 4.2e-20 72.3 3.2 6.8e-20 71.6 3.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP10571.1 - 3.3e-06 27.2 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFP10571.1 - 0.00041 19.9 0.0 0.0023 17.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP10571.1 - 0.00045 19.8 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Peptidase_C2 PF00648.21 KFP10574.1 - 1.7e-109 365.4 0.0 1.9e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C47 PF05543.13 KFP10574.1 - 0.00036 20.2 0.1 0.00061 19.4 0.1 1.3 1 0 0 1 1 1 1 Staphopain peptidase C47 HflK_N PF12221.8 KFP10574.1 - 0.97 9.5 6.8 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Acyltransferase PF01553.21 KFP10576.1 - 2.9e-23 82.0 0.0 5.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KFP10576.1 - 2.8e-20 72.2 2.9 5.3e-20 71.3 0.1 2.4 2 0 0 2 2 2 1 Acyltransferase C-terminus Lbh PF15317.6 KFP10577.1 - 1.1e-28 100.0 2.2 1.3e-28 99.8 2.2 1.0 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Yippee-Mis18 PF03226.14 KFP10579.1 - 3.6e-14 52.8 0.1 4.3e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFP10579.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 KFP10579.1 - 0.0015 18.8 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I HNH_5 PF14279.6 KFP10579.1 - 0.0031 17.3 0.2 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.15 KFP10579.1 - 0.0082 16.0 0.7 0.042 13.8 0.4 2.0 1 1 1 2 2 2 1 Recombination endonuclease VII HECT_2 PF09814.9 KFP10579.1 - 0.072 11.9 0.9 0.23 10.3 0.0 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Sgf11 PF08209.11 KFP10579.1 - 0.19 11.3 2.4 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Ank_5 PF13857.6 KFP10580.1 - 6.7e-07 29.5 0.0 5.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP10580.1 - 8.2e-07 29.5 0.2 0.00081 19.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP10580.1 - 7.2e-06 26.0 1.0 0.046 14.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFP10580.1 - 3e-05 24.5 0.2 0.033 14.8 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP10580.1 - 0.0026 18.1 0.0 0.0026 18.1 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeat ALMS_repeat PF18727.1 KFP10580.1 - 0.022 14.6 0.5 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Alstrom syndrome repeat CAP_GLY PF01302.25 KFP10582.1 - 1.9e-74 245.6 4.3 2.4e-24 85.1 0.5 3.3 3 0 0 3 3 3 3 CAP-Gly domain Ank_2 PF12796.7 KFP10582.1 - 2e-11 44.3 0.7 8.2e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10582.1 - 2e-06 28.3 0.2 0.0002 21.9 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP10582.1 - 3e-05 24.3 4.6 0.016 15.7 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP10582.1 - 0.00045 20.5 2.2 1.1 10.0 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFP10582.1 - 0.0093 16.3 2.3 1.5 9.2 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Tubulin-binding PF00418.19 KFP10582.1 - 0.04 14.0 0.4 0.11 12.6 0.4 1.8 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat TrkA_C PF02080.21 KFP10582.1 - 0.095 12.5 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain CLASP_N PF12348.8 KFP10583.1 - 4e-18 65.8 1.4 4e-18 65.8 1.4 2.7 3 0 0 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 KFP10583.1 - 1.4e-07 31.7 4.9 0.031 14.5 0.1 3.8 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KFP10583.1 - 3.8e-06 27.2 4.8 0.036 14.4 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KFP10583.1 - 0.00018 21.5 1.8 2.6 8.5 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat UME PF08064.13 KFP10583.1 - 0.0011 18.8 2.0 0.44 10.5 0.3 3.5 3 1 0 3 3 3 1 UME (NUC010) domain Gcn1_N PF12074.8 KFP10583.1 - 0.0052 16.1 0.5 0.024 13.9 0.1 2.3 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 KFP10583.1 - 0.0053 17.2 3.1 12 6.6 0.0 5.1 5 1 1 6 6 6 1 HEAT-like repeat NUC173 PF08161.12 KFP10583.1 - 0.0067 16.1 2.4 0.88 9.2 0.3 2.6 2 0 0 2 2 2 2 NUC173 domain DNA_alkylation PF08713.11 KFP10583.1 - 0.11 12.2 0.6 1.9 8.1 0.0 2.9 2 1 1 3 3 3 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 KFP10583.1 - 0.46 11.1 3.0 41 4.9 0.1 3.7 3 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region Flavoprotein PF02441.19 KFP10584.1 - 0.021 14.6 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Flavoprotein Utp12 PF04003.12 KFP10586.1 - 4.6e-24 84.8 1.6 8.4e-24 83.9 1.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KFP10586.1 - 7.9e-11 42.3 13.4 0.00013 22.7 0.9 4.5 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10586.1 - 1.1e-09 38.5 0.3 0.0051 17.1 0.0 4.0 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP10586.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain UTP15_C PF09384.10 KFP10586.1 - 0.02 14.6 0.2 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 UTP15 C terminal Saw1 PF11561.8 KFP10586.1 - 2 7.9 5.7 1.2 8.6 3.1 1.8 2 0 0 2 2 2 0 Single strand annealing-weakened 1 GCD14 PF08704.10 KFP10587.1 - 1.6e-18 67.3 0.0 2.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFP10587.1 - 4.5e-08 33.1 0.0 6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFP10587.1 - 4.2e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP10587.1 - 1.6e-06 28.8 0.0 3e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFP10587.1 - 0.0002 22.4 0.0 0.0003 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP10587.1 - 0.002 18.7 0.0 0.0038 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP10587.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFP10587.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KFP10587.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 KFP10587.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 KFP10587.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 KFP10587.1 - 0.17 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 KFP10587.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Spy1 PF11357.8 KFP10588.1 - 7.6e-57 191.2 5.2 1e-56 190.8 5.2 1.2 1 0 0 1 1 1 1 Cell cycle regulatory protein Thyroglobulin_1 PF00086.18 KFP10589.1 - 1.3e-10 40.8 3.6 1.3e-10 40.8 3.6 2.1 1 1 1 2 2 2 1 Thyroglobulin type-1 repeat Stevor PF17410.2 KFP10589.1 - 0.0005 19.7 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 KFP10589.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EpCAM_N PF18635.1 KFP10589.1 - 0.13 12.4 7.2 0.46 10.7 7.2 2.0 1 0 0 1 1 1 0 Epithelial cell adhesion molecule N-terminal domain DAG1 PF05454.11 KFP10589.1 - 1.2 8.5 4.0 3.1 7.1 3.6 1.7 1 1 1 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MutS_V PF00488.21 KFP10590.1 - 2e-86 288.9 0.6 3.8e-86 287.9 0.6 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFP10590.1 - 3.2e-37 128.6 1.6 3.2e-37 128.6 1.6 2.5 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 KFP10590.1 - 1.4e-22 80.4 0.3 3.9e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KFP10590.1 - 2.3e-20 72.8 2.3 6.1e-20 71.4 2.3 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KFP10590.1 - 4.3e-05 23.7 0.0 0.00017 21.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 KFP10590.1 - 0.0017 18.0 0.0 0.0056 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF2935 PF11155.8 KFP10590.1 - 0.014 15.7 0.7 6.2 7.2 0.3 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) DUF3800 PF12686.7 KFP10590.1 - 0.37 11.4 1.7 1.6 9.3 1.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Ion_trans_2 PF07885.16 KFP10592.1 - 4.4e-21 74.6 20.1 1.5e-15 56.9 8.5 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFP10592.1 - 0.16 11.2 15.4 0.12 11.6 6.1 2.2 2 0 0 2 2 2 0 Ion transport protein MutS_V PF00488.21 KFP10594.1 - 1.9e-72 243.3 0.1 3.3e-72 242.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFP10594.1 - 4.1e-41 141.3 1.5 7.2e-40 137.3 0.1 3.0 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.20 KFP10594.1 - 5.3e-34 116.8 0.1 1.5e-33 115.4 0.1 1.8 1 0 0 1 1 1 1 MutS domain I PWWP PF00855.17 KFP10594.1 - 9.7e-22 77.2 0.0 3.4e-21 75.5 0.0 2.0 1 0 0 1 1 1 1 PWWP domain MutS_IV PF05190.18 KFP10594.1 - 1e-17 64.2 0.2 3.3e-17 62.6 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KFP10594.1 - 1.2e-13 51.5 1.5 2e-13 50.8 0.1 2.2 2 1 0 2 2 2 1 MutS domain II Beta_helix PF13229.6 KFP10595.1 - 1.9e-78 261.8 69.5 1.1e-27 96.8 11.2 4.8 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 KFP10595.1 - 3.9e-41 140.9 30.0 1.5e-17 63.7 8.8 3.9 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 KFP10595.1 - 6.7e-16 57.9 0.3 1.3e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.20 KFP10595.1 - 4.6e-09 36.3 13.1 4.6e-09 36.3 13.1 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.33 KFP10595.1 - 5.1e-08 32.6 0.3 5.1e-08 32.6 0.3 1.8 2 0 0 2 2 2 1 F-box domain 7tm_1 PF00001.21 KFP10596.1 - 1.6e-36 126.0 21.2 2.2e-36 125.5 21.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 KFP10596.1 - 6.6e-15 54.6 6.8 0.00018 21.2 0.2 4.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFP10596.1 - 7.1e-12 45.4 0.1 6.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) GnHR_trans PF12369.8 KFP10596.1 - 0.0093 16.7 0.5 0.018 15.8 0.5 1.6 1 0 0 1 1 1 1 Gonadotropin hormone receptor transmembrane region LRR_9 PF14580.6 KFP10596.1 - 0.075 12.5 0.2 0.21 11.1 0.2 1.7 1 0 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 KFP10596.1 - 0.14 12.6 10.7 0.11 12.9 0.5 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Laminin_G_2 PF02210.24 KFP10599.1 - 5.2e-112 369.6 6.7 9.8e-29 100.5 0.0 5.1 5 0 0 5 5 5 4 Laminin G domain Laminin_G_1 PF00054.23 KFP10599.1 - 2.1e-76 254.4 1.9 7.5e-25 87.7 0.0 5.4 4 1 0 4 4 4 4 Laminin G domain Laminin_G_3 PF13385.6 KFP10599.1 - 2.2e-14 53.9 1.0 0.03 14.5 0.0 4.3 4 0 0 4 4 4 4 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP10599.1 - 4.8e-09 36.4 17.5 9.6e-06 25.8 6.7 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFP10599.1 - 5.1e-05 23.7 14.7 0.016 15.9 5.3 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF DUF1080 PF06439.11 KFP10599.1 - 0.0019 18.4 0.0 5.5 7.1 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1080) Plasmod_Pvs28 PF06247.11 KFP10599.1 - 4.6 7.6 10.6 0.11 12.8 1.7 2.5 2 0 0 2 2 2 0 Pvs28 EGF domain TNF PF00229.18 KFP10601.1 - 1.5e-26 92.8 0.1 3.3e-26 91.7 0.0 1.5 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family Voltage_CLC PF00654.20 KFP10602.1 - 2.8e-108 362.3 22.0 2.8e-108 362.3 22.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFP10602.1 - 7.3e-15 55.2 2.5 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain RGCC PF15151.6 KFP10603.1 - 1e-45 155.3 0.2 1.2e-45 155.1 0.2 1.0 1 0 0 1 1 1 1 Response gene to complement 32 protein family Mst1_SARAH PF11629.8 KFP10603.1 - 1.5 9.0 6.2 15 5.8 0.3 3.3 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 7tm_1 PF00001.21 KFP10604.1 - 3.7e-38 131.3 11.3 4.5e-38 131.1 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP10604.1 - 0.089 12.5 8.4 0.44 10.2 8.4 1.9 1 1 0 1 1 1 0 Olfactory receptor Mito_carr PF00153.27 KFP10605.1 - 2.1e-47 159.0 0.3 1.1e-21 76.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KFP10606.1 - 2.2e-15 56.2 0.1 3.9e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 KFP10606.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Ras PF00071.22 KFP10607.1 - 1.9e-20 73.1 0.0 2.2e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP10607.1 - 6.6e-07 29.6 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP10607.1 - 0.00048 19.6 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family tRNA-synt_1g PF09334.11 KFP10608.1 - 2.6e-81 273.4 0.0 5e-81 272.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFP10608.1 - 4e-13 48.5 0.0 2.7e-11 42.4 0.0 2.7 1 1 2 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFP10608.1 - 7.4e-06 26.0 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFP10608.1 - 9.4e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HCO3_cotransp PF00955.21 KFP10609.1 - 2.4e-244 811.9 8.4 3.1e-244 811.5 8.4 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP10609.1 - 1.5e-102 343.0 0.1 1.5e-102 343.0 0.1 1.6 2 0 0 2 2 2 1 Band 3 cytoplasmic domain MIP PF00230.20 KFP10610.1 - 1.8e-59 201.3 9.9 3.8e-59 200.2 9.9 1.5 1 1 0 1 1 1 1 Major intrinsic protein DUF2070 PF09843.9 KFP10610.1 - 5.9 5.1 10.1 3.4 5.9 4.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) MIP PF00230.20 KFP10611.1 - 4.2e-74 249.1 11.3 4.8e-74 248.9 11.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein FA_desaturase PF00487.24 KFP10611.1 - 8.4 6.1 8.3 8.9 6.1 0.0 2.6 2 1 0 2 2 2 0 Fatty acid desaturase Bax1-I PF01027.20 KFP10612.1 - 2.7e-12 47.0 13.2 3.1e-12 46.7 13.2 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Bin3 PF06859.12 KFP10613.1 - 2.1e-19 70.1 0.0 2.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 KFP10613.1 - 1.1e-05 26.1 0.0 0.0011 19.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP10613.1 - 1.4e-05 24.9 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP10613.1 - 0.0017 18.9 0.0 0.018 15.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP10613.1 - 0.0049 17.5 0.0 0.037 14.7 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP10613.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Filament PF00038.21 KFP10614.1 - 2.2e-75 254.1 33.0 2.6e-75 253.9 33.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein NSP2-B_epitope PF14757.6 KFP10614.1 - 0.078 12.7 0.8 0.18 11.4 0.1 1.9 1 1 1 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Keratin_2_head PF16208.5 KFP10614.1 - 0.21 11.7 0.0 0.31 11.2 0.0 1.2 1 0 0 1 1 1 0 Keratin type II head V_ATPase_I PF01496.19 KFP10614.1 - 0.49 8.3 22.2 0.28 9.1 3.5 2.9 1 1 1 3 3 3 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KFP10614.1 - 2.4 7.4 31.8 1.8 7.9 5.6 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KFP10614.1 - 3.6 7.7 30.4 0.14 12.2 5.1 4.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 KFP10614.1 - 5.6 7.5 11.7 28 5.3 0.0 4.3 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Dna2 PF08696.11 KFP10614.1 - 8.9 6.1 10.4 0.32 10.8 2.4 2.3 1 1 2 3 3 3 0 DNA replication factor Dna2 Filament PF00038.21 KFP10616.1 - 5.3e-118 394.1 38.1 6.1e-118 393.9 38.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10616.1 - 8.1e-18 65.1 7.4 8.1e-18 65.1 7.4 3.0 2 1 0 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP10616.1 - 8.1e-06 25.9 38.0 0.00057 19.9 2.3 3.9 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KFP10616.1 - 0.0011 17.9 37.4 0.0057 15.6 8.7 3.7 1 1 3 4 4 4 2 Spc7 kinetochore protein CALCOCO1 PF07888.11 KFP10616.1 - 0.0024 16.8 33.1 4.3 6.1 33.1 2.1 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 KFP10616.1 - 0.0037 17.4 28.4 0.076 13.1 4.3 3.8 1 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 KFP10616.1 - 0.0045 17.2 28.0 0.016 15.4 3.5 3.4 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KFP10616.1 - 0.0046 17.0 30.0 0.13 12.3 4.3 3.9 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 KFP10616.1 - 0.028 12.6 25.0 0.41 8.8 6.5 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KFP10616.1 - 0.03 14.6 30.0 0.018 15.3 5.7 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KFP10616.1 - 0.1 11.9 34.4 0.14 11.5 10.1 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding B2 PF11473.8 KFP10616.1 - 0.15 11.9 0.5 3.5 7.5 0.1 2.7 2 0 0 2 2 2 0 RNA binding protein B2 DUF1451 PF07295.11 KFP10616.1 - 0.39 10.7 18.1 0.57 10.2 3.7 2.8 2 1 1 3 3 3 0 Zinc-ribbon containing domain APG6_N PF17675.1 KFP10616.1 - 0.54 10.8 42.3 0.078 13.5 7.8 4.3 1 1 3 4 4 4 0 Apg6 coiled-coil region TraC PF07820.12 KFP10616.1 - 0.75 10.2 13.0 8 6.9 7.5 3.5 3 0 0 3 3 3 0 TraC-like protein YvrJ PF12841.7 KFP10616.1 - 0.91 9.1 3.0 17 5.1 0.0 3.3 4 0 0 4 4 3 0 YvrJ protein family Fib_alpha PF08702.10 KFP10616.1 - 1.3 9.2 23.5 0.071 13.3 1.2 3.9 1 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP10616.1 - 1.5 8.9 15.2 5 7.2 0.9 4.3 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) ERM PF00769.19 KFP10616.1 - 1.6 8.5 34.2 5 6.9 6.8 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DASH_Duo1 PF08651.10 KFP10616.1 - 2 8.3 9.5 3 7.7 1.0 4.0 3 1 1 4 4 4 0 DASH complex subunit Duo1 BRE1 PF08647.11 KFP10616.1 - 2.8 8.1 33.7 0.18 11.9 6.2 4.3 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 KFP10616.1 - 3.5 5.0 32.3 0.95 6.9 14.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 KFP10616.1 - 3.8 6.7 30.7 0.2 11.0 4.3 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) COMP PF11598.8 KFP10616.1 - 5.8 7.5 8.1 7.8 7.1 1.8 3.8 4 0 0 4 4 3 0 Cartilage oligomeric matrix protein ACCA PF03255.14 KFP10616.1 - 6.2 6.7 21.0 2.8 7.8 3.2 4.1 1 1 3 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Rab5-bind PF09311.11 KFP10616.1 - 7.8 5.8 32.4 0.087 12.2 9.2 3.3 1 1 1 2 2 2 0 Rabaptin-like protein Filament PF00038.21 KFP10617.1 - 1.8e-113 379.3 28.4 2.1e-113 379.0 28.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10617.1 - 1.4e-20 74.0 38.4 1.9e-14 54.1 8.8 3.3 2 1 1 3 3 3 2 Keratin type II head ADIP PF11559.8 KFP10617.1 - 0.0023 18.0 4.0 0.0023 18.0 4.0 3.9 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KFP10617.1 - 0.0045 16.2 2.4 0.0045 16.2 2.4 2.8 1 1 1 3 3 3 1 Myosin-like coiled-coil protein Spc7 PF08317.11 KFP10617.1 - 0.006 15.5 24.6 0.24 10.3 11.7 2.8 1 1 1 2 2 2 2 Spc7 kinetochore protein BRE1 PF08647.11 KFP10617.1 - 0.0079 16.2 2.9 0.0079 16.2 2.9 4.3 3 2 1 4 4 4 1 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 KFP10617.1 - 0.0092 16.0 25.7 0.026 14.6 5.6 3.8 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KFP10617.1 - 0.013 15.0 5.6 0.013 15.0 5.6 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 KFP10617.1 - 0.017 15.1 21.5 0.062 13.3 4.1 3.8 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KFP10617.1 - 0.024 14.7 11.5 0.06 13.4 0.7 3.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KFP10617.1 - 0.027 14.6 0.4 0.027 14.6 0.4 3.1 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DHR10 PF18595.1 KFP10617.1 - 0.028 14.5 1.7 0.028 14.5 1.7 3.9 3 2 1 4 4 3 0 Designed helical repeat protein 10 domain CCDC92 PF14916.6 KFP10617.1 - 0.04 13.7 3.4 0.046 13.5 0.0 2.9 4 0 0 4 4 3 0 Coiled-coil domain of unknown function CHDCT2 PF08074.11 KFP10617.1 - 0.076 13.2 11.9 0.055 13.6 1.2 2.7 1 1 1 3 3 3 0 CHDCT2 (NUC038) domain DUF4094 PF13334.6 KFP10617.1 - 0.12 12.8 0.7 0.51 10.8 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Alanine_zipper PF11839.8 KFP10617.1 - 0.14 12.6 5.6 0.5 10.8 5.6 1.9 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein mRNA_decap_C PF16741.5 KFP10617.1 - 0.14 11.5 0.0 6 6.3 0.0 2.5 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus Jnk-SapK_ap_N PF09744.9 KFP10617.1 - 0.2 11.9 19.2 0.096 12.9 0.9 3.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KFP10617.1 - 0.25 11.5 11.1 24 5.2 0.2 4.9 4 1 0 4 4 4 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 KFP10617.1 - 0.32 11.0 14.3 2.7 8.1 1.2 4.1 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) STAT_alpha PF01017.20 KFP10617.1 - 0.79 9.6 13.4 1.4 8.8 2.1 2.9 2 1 1 3 3 3 0 STAT protein, all-alpha domain Tropomyosin_1 PF12718.7 KFP10617.1 - 0.92 9.7 24.0 0.076 13.2 6.2 3.7 2 1 2 4 4 4 0 Tropomyosin like DUF4164 PF13747.6 KFP10617.1 - 1.2 9.4 14.6 1 9.7 0.9 3.8 3 1 1 4 4 3 0 Domain of unknown function (DUF4164) DUF5082 PF16888.5 KFP10617.1 - 1.3 9.3 19.2 0.067 13.5 0.8 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 KFP10617.1 - 1.6 8.8 20.5 0.49 10.5 2.2 3.4 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 KFP10617.1 - 1.6 9.1 8.9 22 5.5 0.3 4.1 3 1 1 4 4 4 0 TSC-22/dip/bun family ZapB PF06005.12 KFP10617.1 - 1.6 9.2 13.6 5 7.6 1.0 4.1 3 2 0 3 3 3 0 Cell division protein ZapB DUF4140 PF13600.6 KFP10617.1 - 1.8 9.1 15.9 33 5.0 3.5 4.8 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.9 KFP10617.1 - 1.8 8.5 22.8 0.18 11.8 2.7 4.3 1 1 1 4 4 4 0 Axonemal dynein light chain TMF_TATA_bd PF12325.8 KFP10617.1 - 1.8 8.8 19.6 2.7 8.2 4.7 4.1 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TRAF_BIRC3_bd PF16673.5 KFP10617.1 - 1.9 8.3 5.8 3.5 7.5 0.5 3.0 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain PRKG1_interact PF15898.5 KFP10617.1 - 2.6 9.0 17.7 7.4 7.5 3.1 4.0 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 KFP10617.1 - 2.8 8.1 17.7 4.7 7.4 1.9 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 KFP10617.1 - 2.8 8.3 13.9 26 5.2 0.3 4.2 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 KFP10617.1 - 3 7.8 18.6 2.8 7.9 1.0 3.6 2 1 0 3 3 3 0 Laminin Domain II ACCA PF03255.14 KFP10617.1 - 3.1 7.6 13.9 5.2 6.9 0.4 3.7 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LPP PF04728.13 KFP10617.1 - 3.7 8.0 15.1 9.5 6.7 3.8 5.1 4 2 0 4 4 4 0 Lipoprotein leucine-zipper Lebercilin PF15619.6 KFP10617.1 - 4.1 7.0 23.7 0.33 10.6 6.0 3.7 1 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.10 KFP10617.1 - 4.9 7.5 19.3 11 6.5 0.7 5.6 3 3 2 5 5 5 0 Tup N-terminal V_ATPase_I PF01496.19 KFP10617.1 - 6.3 4.6 18.0 0.37 8.7 2.3 2.8 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 KFP10617.1 - 6.6 7.3 29.5 0.22 12.1 6.7 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF883 PF05957.13 KFP10617.1 - 7 7.3 15.8 5.2 7.8 4.9 4.2 4 1 1 5 5 4 0 Bacterial protein of unknown function (DUF883) Rota_NSP4 PF01452.16 KFP10617.1 - 7.2 6.3 7.1 3 7.5 0.3 3.2 2 1 2 4 4 4 0 Rotavirus non structural protein TMF_DNA_bd PF12329.8 KFP10617.1 - 7.9 6.6 18.3 0.28 11.2 0.6 4.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Bap31_Bap29_C PF18035.1 KFP10617.1 - 9.5 6.3 7.2 3 7.9 0.1 3.7 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 KFP10618.1 - 5.9e-113 377.6 35.2 6.8e-113 377.3 35.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10618.1 - 1e-26 94.0 58.9 6.1e-26 91.5 31.1 3.2 2 1 0 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP10618.1 - 1.9e-08 34.4 32.4 2e-06 27.9 2.9 3.8 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KFP10618.1 - 8.8e-06 25.9 26.9 0.00027 21.0 2.0 3.8 2 2 1 3 3 3 2 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KFP10618.1 - 0.00026 20.0 34.2 0.011 14.6 13.1 3.2 1 1 2 3 3 3 3 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFP10618.1 - 0.0014 18.6 6.2 0.0014 18.6 6.2 3.7 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 KFP10618.1 - 0.0016 17.7 22.9 0.073 12.2 22.4 2.6 1 1 0 1 1 1 1 Myosin-like coiled-coil protein Tropomyosin_1 PF12718.7 KFP10618.1 - 0.002 18.3 8.9 0.002 18.3 8.9 3.8 2 1 2 4 4 3 1 Tropomyosin like Golgin_A5 PF09787.9 KFP10618.1 - 0.0083 15.6 29.4 0.012 15.1 7.8 2.9 1 1 2 3 3 3 2 Golgin subfamily A member 5 TSNAXIP1_N PF15739.5 KFP10618.1 - 0.016 15.6 0.8 0.016 15.6 0.8 4.2 2 1 3 6 6 6 0 Translin-associated factor X-interacting N-terminus GAS PF13851.6 KFP10618.1 - 0.026 13.9 31.3 0.023 14.1 7.5 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding LPP PF04728.13 KFP10618.1 - 0.031 14.7 0.4 0.031 14.7 0.4 4.5 4 1 1 5 5 4 0 Lipoprotein leucine-zipper Phage_GP20 PF06810.11 KFP10618.1 - 0.033 14.0 23.3 0.026 14.3 4.0 4.0 2 1 2 4 4 4 0 Phage minor structural protein GP20 SlyX PF04102.12 KFP10618.1 - 0.036 14.7 1.2 0.036 14.7 1.2 4.7 4 2 2 6 6 4 0 SlyX Bap31_Bap29_C PF18035.1 KFP10618.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.6 4 1 0 4 4 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Baculo_PEP_C PF04513.12 KFP10618.1 - 0.17 11.9 19.0 0.73 9.9 2.0 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alanine_zipper PF11839.8 KFP10618.1 - 0.2 12.1 7.5 0.37 11.2 6.2 2.2 2 0 0 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein BRE1 PF08647.11 KFP10618.1 - 0.22 11.6 31.3 0.026 14.6 4.3 4.4 2 2 2 4 4 4 0 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 KFP10618.1 - 0.23 11.8 19.9 2.5 8.4 0.3 4.4 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KFP10618.1 - 0.24 11.4 18.1 0.1 12.7 1.0 4.5 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) DUF4988 PF16378.5 KFP10618.1 - 0.25 11.0 9.6 8.9 5.9 0.3 3.7 3 1 1 4 4 4 0 Domain of unknown function DUF3450 PF11932.8 KFP10618.1 - 0.35 10.1 32.4 0.017 14.4 4.8 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KFP10618.1 - 0.36 11.4 38.2 0.042 14.4 5.0 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region COG5 PF10392.9 KFP10618.1 - 0.36 11.0 11.3 0.35 11.0 2.2 2.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF3584 PF12128.8 KFP10618.1 - 0.42 8.1 29.2 1.7 6.1 29.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 KFP10618.1 - 0.52 10.6 26.5 0.42 10.9 5.6 3.5 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 KFP10618.1 - 0.57 10.5 13.2 5.8 7.3 0.3 4.5 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF4407 PF14362.6 KFP10618.1 - 0.61 9.4 25.0 2.2e+03 -2.3 25.0 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GCP_C_terminal PF04130.13 KFP10618.1 - 0.79 9.1 13.6 12 5.2 13.6 2.1 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal RPW8 PF05659.11 KFP10618.1 - 1 9.1 7.3 4.8 6.9 0.4 3.3 2 2 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fib_alpha PF08702.10 KFP10618.1 - 1 9.6 23.9 0.46 10.7 3.5 3.7 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 KFP10618.1 - 1.1 9.5 18.9 2 8.7 0.4 5.1 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II ANAPC4 PF12896.7 KFP10618.1 - 1.2 8.5 8.2 0.61 9.5 0.9 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 SOGA PF11365.8 KFP10618.1 - 1.4 10.1 19.8 0.52 11.5 2.7 3.4 2 1 2 4 4 3 0 Protein SOGA TolA_bind_tri PF16331.5 KFP10618.1 - 1.4 9.0 21.1 2.5 8.3 0.3 5.4 5 1 1 6 6 5 0 TolA binding protein trimerisation PRKG1_interact PF15898.5 KFP10618.1 - 1.7 9.6 24.5 3.1 8.8 3.5 4.0 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain FlaC_arch PF05377.11 KFP10618.1 - 3.1 8.3 17.4 2.7 8.5 0.2 5.4 5 2 1 6 6 5 0 Flagella accessory protein C (FlaC) DHR10 PF18595.1 KFP10618.1 - 3.2 7.9 31.3 0.023 14.8 6.6 4.1 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain CRR7 PF12095.8 KFP10618.1 - 3.3 8.2 11.4 1.2 9.7 0.9 4.0 3 1 1 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF948 PF06103.11 KFP10618.1 - 4 7.8 9.7 3.5 8.0 1.0 3.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1192 PF06698.11 KFP10618.1 - 4 7.6 7.4 18 5.5 0.2 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) YojJ PF10372.9 KFP10618.1 - 6.1 7.0 10.2 5.4 7.2 0.0 3.7 5 0 0 5 5 2 0 Bacterial membrane-spanning protein N-terminus Cob_adeno_trans PF01923.18 KFP10618.1 - 6.3 6.9 12.2 14 5.8 0.5 3.3 1 1 2 3 3 3 0 Cobalamin adenosyltransferase TMF_DNA_bd PF12329.8 KFP10618.1 - 6.4 6.9 27.2 0.045 13.7 2.4 4.8 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Syntaxin-6_N PF09177.11 KFP10618.1 - 6.5 7.4 20.6 6.2 7.4 5.3 4.4 1 1 2 4 4 4 0 Syntaxin 6, N-terminal ZapB PF06005.12 KFP10618.1 - 6.7 7.2 26.9 3.4e+02 1.8 10.3 4.6 2 2 0 2 2 2 0 Cell division protein ZapB FPP PF05911.11 KFP10618.1 - 6.8 4.7 29.8 0.75 7.9 8.6 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Ribosomal_S30AE PF02482.19 KFP10618.1 - 6.8 7.5 8.0 0.76 10.6 1.6 2.5 3 1 0 3 3 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Jnk-SapK_ap_N PF09744.9 KFP10618.1 - 7.2 6.8 29.8 3.2 8.0 6.3 3.5 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 COMP PF11598.8 KFP10618.1 - 7.5 7.1 7.3 28 5.3 0.8 4.0 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein UPF0242 PF06785.11 KFP10618.1 - 7.9 6.5 33.0 0.62 10.1 7.0 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Tup_N PF08581.10 KFP10618.1 - 8.1 6.8 26.5 5.2 7.5 1.4 5.9 1 1 6 7 7 7 0 Tup N-terminal ApoLp-III PF07464.11 KFP10618.1 - 8.7 6.4 20.1 0.14 12.2 2.2 3.6 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Nbl1_Borealin_N PF10444.9 KFP10618.1 - 8.9 6.0 12.5 4.8 6.9 0.0 5.3 6 1 0 6 6 5 0 Nbl1 / Borealin N terminal DUF2203 PF09969.9 KFP10618.1 - 9 7.1 18.0 3.6 8.3 0.4 3.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 KFP10619.1 - 3.8e-114 381.5 36.7 4.4e-114 381.3 36.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10619.1 - 3.2e-29 102.1 33.4 3.2e-29 102.1 33.4 3.0 2 1 0 2 2 2 1 Keratin type II head CENP-F_leu_zip PF10473.9 KFP10619.1 - 0.00014 21.9 28.2 0.0044 17.0 8.0 3.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 KFP10619.1 - 0.00028 20.2 24.3 0.0036 16.5 13.7 3.0 1 1 2 3 3 3 2 Myosin-like coiled-coil protein Spc7 PF08317.11 KFP10619.1 - 0.00045 19.2 5.3 0.00045 19.2 5.3 3.2 1 1 1 2 2 2 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFP10619.1 - 0.00091 19.3 35.3 0.0019 18.3 11.4 3.9 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 KFP10619.1 - 0.002 18.3 11.4 0.002 18.3 11.4 3.8 2 1 2 4 4 4 1 Tropomyosin like TSNAXIP1_N PF15739.5 KFP10619.1 - 0.0041 17.5 1.3 0.0041 17.5 1.3 4.0 3 1 2 5 5 5 1 Translin-associated factor X-interacting N-terminus Phage_GP20 PF06810.11 KFP10619.1 - 0.0071 16.2 5.6 0.0071 16.2 5.6 3.5 2 1 1 3 3 3 1 Phage minor structural protein GP20 DHR10 PF18595.1 KFP10619.1 - 0.017 15.2 7.4 0.017 15.2 7.4 4.1 3 1 1 4 4 4 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KFP10619.1 - 0.017 15.1 20.1 0.37 10.8 0.8 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KFP10619.1 - 0.026 14.9 0.3 0.026 14.9 0.3 4.8 6 0 0 6 6 4 0 Lipoprotein leucine-zipper SlyX PF04102.12 KFP10619.1 - 0.03 14.9 0.4 0.03 14.9 0.4 4.5 3 1 1 4 4 4 0 SlyX ApoLp-III PF07464.11 KFP10619.1 - 0.032 14.3 1.0 0.032 14.3 1.0 4.0 2 2 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DivIC PF04977.15 KFP10619.1 - 0.036 13.8 1.1 0.036 13.8 1.1 5.0 3 2 2 5 5 5 0 Septum formation initiator AAA_13 PF13166.6 KFP10619.1 - 0.045 12.4 20.6 0.011 14.4 17.2 1.7 1 1 0 1 1 1 0 AAA domain ADIP PF11559.8 KFP10619.1 - 0.046 13.8 28.8 0.063 13.4 10.3 4.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KFP10619.1 - 0.21 11.0 30.5 0.03 13.8 8.4 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KFP10619.1 - 0.26 11.4 19.4 4.1 7.5 0.1 5.4 4 1 1 5 5 5 0 TolA binding protein trimerisation APG6_N PF17675.1 KFP10619.1 - 0.42 11.1 37.4 0.061 13.8 5.5 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF1451 PF07295.11 KFP10619.1 - 0.77 9.8 13.7 1.6 8.7 3.6 2.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF3450 PF11932.8 KFP10619.1 - 0.78 9.0 29.9 0.08 12.2 4.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF2746 PF10874.8 KFP10619.1 - 0.95 9.9 4.7 1.6 9.2 0.2 3.1 2 1 2 4 4 3 0 Protein of unknown function (DUF2746) BRE1 PF08647.11 KFP10619.1 - 1.4 9.1 30.2 0.026 14.6 4.1 4.4 2 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 KFP10619.1 - 1.7 7.1 5.4 1.3 7.4 4.2 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Alanine_zipper PF11839.8 KFP10619.1 - 1.7 9.1 11.2 0.68 10.3 7.8 2.1 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Atg14 PF10186.9 KFP10619.1 - 1.8 7.6 22.5 0.41 9.7 11.1 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4988 PF16378.5 KFP10619.1 - 1.8 8.2 10.0 1.5 8.5 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function UPF0242 PF06785.11 KFP10619.1 - 2 8.5 30.6 2.6 8.1 10.5 3.5 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 KFP10619.1 - 2.4 8.4 26.8 0.97 9.7 2.2 4.5 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 KFP10619.1 - 3.8 7.7 30.7 0.51 10.6 3.9 3.8 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KFP10619.1 - 4.3 7.8 13.9 1.9 8.9 0.1 5.1 4 2 3 7 7 6 0 Flagella accessory protein C (FlaC) Plk4_PB2 PF18409.1 KFP10619.1 - 4.7 7.9 7.6 3.6 8.3 0.4 3.1 2 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 TSC22 PF01166.18 KFP10619.1 - 5 7.5 18.7 13 6.2 0.4 4.9 3 2 3 6 6 5 0 TSC-22/dip/bun family NPV_P10 PF05531.12 KFP10619.1 - 6.2 7.4 14.4 7.1 7.2 1.2 4.3 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.6 KFP10619.1 - 6.5 7.3 23.4 1.5 9.3 2.9 5.0 2 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) ACCA PF03255.14 KFP10619.1 - 7.6 6.4 17.7 3.3 7.6 1.2 4.3 2 1 3 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GAS PF13851.6 KFP10619.1 - 8.2 5.7 34.6 0.061 12.7 9.1 3.3 1 1 1 3 3 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 KFP10619.1 - 8.4 5.6 26.2 1.4e+03 -1.6 26.2 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KFP10619.1 - 9.7 6.4 24.3 2.6 8.2 3.2 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KFP10620.1 - 1e-113 380.1 35.0 1.2e-113 379.9 35.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10620.1 - 3.1e-40 138.0 46.7 3.1e-40 138.0 46.7 2.5 2 1 0 2 2 1 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP10620.1 - 3.5e-07 30.3 29.8 0.00036 20.6 10.9 3.7 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KFP10620.1 - 0.00023 20.0 14.4 0.00023 20.0 14.4 1.9 1 1 0 1 1 1 1 AAA domain Spc7 PF08317.11 KFP10620.1 - 0.0022 16.9 32.7 0.031 13.2 15.6 3.2 1 1 1 3 3 3 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFP10620.1 - 0.0024 17.9 27.8 0.014 15.4 7.0 3.7 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.11 KFP10620.1 - 0.0038 17.3 1.6 0.0038 17.3 1.6 3.1 2 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) MukF_M PF17192.4 KFP10620.1 - 0.0051 16.6 14.1 0.028 14.2 6.6 2.4 2 0 0 2 2 2 1 MukF middle domain ADIP PF11559.8 KFP10620.1 - 0.0089 16.1 26.6 0.055 13.6 2.6 3.8 2 2 0 3 3 3 2 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 KFP10620.1 - 0.014 15.4 1.4 0.014 15.4 1.4 4.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BRE1 PF08647.11 KFP10620.1 - 0.019 15.0 5.1 0.019 15.0 5.1 4.6 2 1 3 5 5 5 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 KFP10620.1 - 0.024 14.0 18.4 0.041 13.2 3.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) mRNA_decap_C PF16741.5 KFP10620.1 - 0.029 13.7 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus Jnk-SapK_ap_N PF09744.9 KFP10620.1 - 0.056 13.7 27.8 0.049 13.8 3.8 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF1451 PF07295.11 KFP10620.1 - 0.086 12.9 14.5 0.17 11.9 3.5 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain DUF1664 PF07889.12 KFP10620.1 - 0.11 12.5 14.3 2.5 8.2 1.2 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DED PF01335.21 KFP10620.1 - 0.38 11.1 2.6 14 6.1 0.1 2.5 2 0 0 2 2 2 0 Death effector domain COMP PF11598.8 KFP10620.1 - 0.7 10.4 5.0 38 4.9 0.5 4.0 4 0 0 4 4 3 0 Cartilage oligomeric matrix protein DUF5082 PF16888.5 KFP10620.1 - 0.87 9.9 23.5 0.13 12.6 4.6 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) TSC22 PF01166.18 KFP10620.1 - 1.2 9.5 13.5 5 7.5 0.2 4.4 3 2 1 4 4 4 0 TSC-22/dip/bun family Rx_N PF18052.1 KFP10620.1 - 1.4 9.2 10.5 0.95 9.8 2.7 3.0 3 0 0 3 3 3 0 Rx N-terminal domain ACCA PF03255.14 KFP10620.1 - 1.8 8.4 17.9 1.3 8.9 0.4 3.7 1 1 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Golgin_A5 PF09787.9 KFP10620.1 - 2 7.8 30.0 0.16 11.4 8.7 3.4 1 1 3 4 4 4 0 Golgin subfamily A member 5 T2SSM PF04612.12 KFP10620.1 - 2.7 8.0 8.6 0.24 11.5 2.4 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Rootletin PF15035.6 KFP10620.1 - 3 7.8 24.5 0.25 11.4 4.8 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FlxA PF14282.6 KFP10620.1 - 3.5 7.7 20.2 0.2 11.7 3.9 3.9 2 1 1 3 3 3 0 FlxA-like protein DUF883 PF05957.13 KFP10620.1 - 3.9 8.1 20.5 1 10.0 6.4 4.6 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Alanine_zipper PF11839.8 KFP10620.1 - 4.3 7.8 11.5 1.4 9.3 7.7 2.1 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein TMF_TATA_bd PF12325.8 KFP10620.1 - 4.4 7.6 24.3 4.5 7.5 5.1 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding T7SS_ESX_EspC PF10824.8 KFP10620.1 - 5.1 7.6 7.0 1.1 9.8 1.8 2.5 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm YlqD PF11068.8 KFP10620.1 - 7.9 6.9 28.2 0.98 9.8 6.0 4.1 1 1 3 4 4 4 0 YlqD protein DUF948 PF06103.11 KFP10620.1 - 8.4 6.7 10.0 5.6 7.3 0.7 3.6 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KFP10620.1 - 9 6.8 36.4 0.27 11.7 11.4 4.1 1 1 3 4 4 4 0 Apg6 coiled-coil region Bap31_Bap29_C PF18035.1 KFP10620.1 - 9.4 6.3 8.6 1.6 8.8 0.2 3.6 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 KFP10621.1 - 3.9e-112 374.9 32.3 4.5e-112 374.7 32.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10621.1 - 2.6e-29 102.4 44.8 2.6e-29 102.4 44.8 2.8 2 1 0 2 2 2 1 Keratin type II head ATG16 PF08614.11 KFP10621.1 - 7.4e-06 26.3 25.0 0.00012 22.4 6.0 3.1 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KFP10621.1 - 0.00086 19.4 29.0 0.0019 18.3 3.3 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein COG5 PF10392.9 KFP10621.1 - 0.0011 19.1 0.7 0.004 17.3 0.5 2.0 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Spc7 PF08317.11 KFP10621.1 - 0.0013 17.6 28.7 0.0022 17.0 2.2 3.0 1 1 2 3 3 3 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFP10621.1 - 0.0092 16.0 21.8 0.15 12.1 4.6 3.3 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KFP10621.1 - 0.017 15.2 4.8 0.017 15.2 4.8 4.4 2 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 KFP10621.1 - 0.038 14.0 0.4 0.038 14.0 0.4 4.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus mRNA_decap_C PF16741.5 KFP10621.1 - 0.077 12.3 0.1 9.9 5.6 0.0 2.4 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus ADIP PF11559.8 KFP10621.1 - 0.15 12.1 24.6 0.54 10.3 2.9 3.9 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 KFP10621.1 - 0.16 11.7 26.3 0.017 14.8 6.6 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.10 KFP10621.1 - 0.35 11.2 19.4 2.7 8.3 0.1 5.2 2 2 4 6 6 6 0 Tup N-terminal DUF745 PF05335.13 KFP10621.1 - 0.52 10.0 16.8 0.55 9.9 6.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Ribosomal_S30AE PF02482.19 KFP10621.1 - 0.72 10.7 3.1 0.81 10.5 0.8 2.3 2 2 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Tropomyosin_1 PF12718.7 KFP10621.1 - 0.95 9.6 27.9 0.073 13.2 8.1 3.4 2 1 2 4 4 4 0 Tropomyosin like ApoLp-III PF07464.11 KFP10621.1 - 2.5 8.2 12.9 0.33 11.0 1.2 3.5 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.10 KFP10621.1 - 3.2 8.0 20.3 0.53 10.5 1.2 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family SPATA1_C PF15743.5 KFP10621.1 - 3.7 7.6 21.0 0.31 11.1 5.9 2.8 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Nbl1_Borealin_N PF10444.9 KFP10621.1 - 4 7.1 10.1 4.7 6.9 0.0 4.5 4 1 0 4 4 4 0 Nbl1 / Borealin N terminal DUF5082 PF16888.5 KFP10621.1 - 6.1 7.1 20.5 1.8 8.8 1.9 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) COMP PF11598.8 KFP10621.1 - 6.7 7.3 7.2 34 5.0 0.4 3.4 4 0 0 4 4 3 0 Cartilage oligomeric matrix protein DUF3450 PF11932.8 KFP10621.1 - 8.8 5.6 24.8 1.3 8.2 1.7 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Filament PF00038.21 KFP10622.1 - 8.2e-107 357.4 39.9 9.6e-107 357.2 39.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10622.1 - 1.9e-24 86.6 77.1 1.9e-24 86.6 77.1 4.1 2 2 2 4 4 2 1 Keratin type II head ATG16 PF08614.11 KFP10622.1 - 0.0003 21.1 31.3 0.0043 17.3 4.3 2.6 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFP10622.1 - 0.0012 17.8 12.3 0.0012 17.8 12.3 3.0 1 1 2 3 3 3 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFP10622.1 - 0.0022 18.1 42.0 0.014 15.4 1.6 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KFP10622.1 - 0.0026 16.5 19.3 0.0026 16.5 19.3 1.8 1 1 0 1 1 1 1 AAA domain JIP_LZII PF16471.5 KFP10622.1 - 0.1 12.7 23.0 0.16 12.2 0.7 4.9 4 2 1 5 5 5 0 JNK-interacting protein leucine zipper II Tropomyosin_1 PF12718.7 KFP10622.1 - 0.15 12.2 28.9 0.22 11.7 0.6 3.4 3 0 0 3 3 3 0 Tropomyosin like Taxilin PF09728.9 KFP10622.1 - 0.63 9.2 28.0 1.2 8.3 24.8 2.4 1 1 1 2 2 2 0 Myosin-like coiled-coil protein FPP PF05911.11 KFP10622.1 - 0.83 7.8 27.7 1.7 6.7 27.7 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KFP10622.1 - 0.83 9.7 34.9 0.57 10.2 14.9 3.6 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KFP10622.1 - 1.1 9.3 20.5 7.1 6.7 2.9 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 KFP10622.1 - 1.3 7.5 28.6 0.85 8.2 5.7 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A ADIP PF11559.8 KFP10622.1 - 1.4 9.0 35.3 0.095 12.8 13.1 3.6 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.13 KFP10622.1 - 1.9 9.2 19.0 1.8 9.2 6.8 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) LPP PF04728.13 KFP10622.1 - 2.8 8.4 13.5 0.092 13.1 0.9 4.2 5 0 0 5 5 4 0 Lipoprotein leucine-zipper AKNA PF12443.8 KFP10622.1 - 2.8 8.6 8.8 1.2 9.9 2.4 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF4618 PF15397.6 KFP10622.1 - 3.7 6.9 34.0 0.47 9.8 17.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 KFP10622.1 - 4.9 7.3 30.5 0.062 13.5 3.5 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KFP10622.1 - 9.4 5.5 25.6 1.8e+04 -6.5 25.7 2.7 1 1 0 1 1 0 0 Domain of unknown function (DUF4407) Rx_N PF18052.1 KFP10622.1 - 9.8 6.5 12.0 11 6.4 3.2 3.2 3 1 0 3 3 3 0 Rx N-terminal domain Filament PF00038.21 KFP10623.1 - 1.2e-114 383.1 30.7 1.4e-114 382.9 30.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Keratin_2_head PF16208.5 KFP10623.1 - 3.8e-36 124.7 44.8 3.8e-36 124.7 44.8 2.4 2 0 0 2 2 2 1 Keratin type II head TPR_MLP1_2 PF07926.12 KFP10623.1 - 1.7e-06 28.1 32.5 0.00061 19.9 2.2 3.8 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 KFP10623.1 - 6.6e-05 22.2 17.6 0.00011 21.5 17.3 1.6 1 1 0 1 1 1 1 Myosin-like coiled-coil protein AAA_13 PF13166.6 KFP10623.1 - 0.00055 18.7 15.1 0.00055 18.7 15.1 1.6 2 1 0 2 2 1 1 AAA domain DHR10 PF18595.1 KFP10623.1 - 0.003 17.6 4.2 0.003 17.6 4.2 4.5 3 2 1 4 4 4 1 Designed helical repeat protein 10 domain ATG16 PF08614.11 KFP10623.1 - 0.0054 17.0 27.2 0.045 14.0 12.0 3.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 KFP10623.1 - 0.0057 16.9 6.3 0.0057 16.9 6.3 3.3 2 1 0 3 3 3 1 JNK_SAPK-associated protein-1 MscS_porin PF12795.7 KFP10623.1 - 0.0057 16.2 9.5 0.0057 16.2 9.5 2.8 3 1 0 3 3 2 1 Mechanosensitive ion channel porin domain Spc7 PF08317.11 KFP10623.1 - 0.0066 15.4 6.0 0.0066 15.4 6.0 3.4 1 1 2 4 4 4 3 Spc7 kinetochore protein COG5 PF10392.9 KFP10623.1 - 0.0069 16.6 1.3 0.0069 16.6 1.3 2.7 2 1 1 3 3 3 1 Golgi transport complex subunit 5 DUF4407 PF14362.6 KFP10623.1 - 0.0087 15.4 17.9 1.7e+02 1.3 17.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KFP10623.1 - 0.017 15.2 5.8 0.017 15.2 5.8 4.1 3 1 0 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KFP10623.1 - 0.026 14.5 18.0 0.3 11.1 0.9 4.3 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 KFP10623.1 - 0.029 14.5 1.5 0.029 14.5 1.5 4.0 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 KFP10623.1 - 0.034 13.6 31.9 0.023 14.2 7.9 3.4 1 1 1 3 3 3 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KFP10623.1 - 0.045 13.8 13.7 0.096 12.7 2.5 4.1 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AKNA PF12443.8 KFP10623.1 - 0.057 14.1 2.3 0.79 10.4 0.3 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF812 PF05667.11 KFP10623.1 - 0.066 12.1 28.0 0.024 13.6 10.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF812) SlyX PF04102.12 KFP10623.1 - 0.066 13.8 0.9 0.066 13.8 0.9 4.7 4 2 1 5 5 5 0 SlyX KxDL PF10241.9 KFP10623.1 - 0.075 13.3 0.4 0.075 13.3 0.4 4.5 3 1 3 6 6 5 0 Uncharacterized conserved protein Bap31_Bap29_C PF18035.1 KFP10623.1 - 0.095 12.7 0.3 0.095 12.7 0.3 4.2 4 2 0 4 4 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Phage_GP20 PF06810.11 KFP10623.1 - 0.11 12.3 26.4 0.065 13.0 7.3 3.9 3 1 0 3 3 2 0 Phage minor structural protein GP20 DUF3584 PF12128.8 KFP10623.1 - 0.14 9.7 23.6 0.21 9.1 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 KFP10623.1 - 0.26 11.3 35.5 0.72 9.9 8.7 4.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 KFP10623.1 - 0.29 11.2 32.2 0.034 14.2 3.7 4.5 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KFP10623.1 - 0.61 10.6 40.0 7.8 7.0 10.9 4.5 2 1 2 4 4 4 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 KFP10623.1 - 0.8 9.9 34.8 0.13 12.4 8.9 4.1 2 1 2 4 4 4 0 Tropomyosin like JIP_LZII PF16471.5 KFP10623.1 - 0.87 9.8 24.3 0.77 10.0 0.5 5.2 5 1 0 5 5 5 0 JNK-interacting protein leucine zipper II STAT_alpha PF01017.20 KFP10623.1 - 0.99 9.3 19.8 0.98 9.3 3.5 3.0 3 0 0 3 3 3 0 STAT protein, all-alpha domain DUF948 PF06103.11 KFP10623.1 - 1.2 9.5 8.0 0.65 10.3 0.5 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 KFP10623.1 - 1.3 9.1 22.3 0.26 11.4 1.1 4.5 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 KFP10623.1 - 1.3 8.3 34.7 0.12 11.7 8.5 3.9 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Rx_N PF18052.1 KFP10623.1 - 1.4 9.3 9.2 0.75 10.1 1.5 3.2 3 1 0 3 3 3 0 Rx N-terminal domain Virulence_fact PF13769.6 KFP10623.1 - 1.5 9.1 5.5 0.29 11.4 0.2 2.5 3 0 0 3 3 1 0 Virulence factor UPF0242 PF06785.11 KFP10623.1 - 1.6 8.8 28.3 1.1 9.3 3.3 3.9 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus She9_MDM33 PF05546.11 KFP10623.1 - 1.8 8.3 12.7 1 9.1 0.4 2.9 2 2 0 2 2 2 0 She9 / Mdm33 family FapA PF03961.13 KFP10623.1 - 2.6 6.5 19.7 1.1 7.8 6.0 2.4 1 1 0 2 2 2 0 Flagellar Assembly Protein A FUSC PF04632.12 KFP10623.1 - 2.6 6.4 4.8 3.7 6.0 3.7 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Plk4_PB2 PF18409.1 KFP10623.1 - 3.4 8.4 5.4 20 5.9 0.7 3.2 2 1 1 3 3 2 0 Polo-like Kinase 4 Polo Box 2 LPP PF04728.13 KFP10623.1 - 3.4 8.1 12.3 2.9 8.4 0.2 4.2 5 0 0 5 5 4 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 KFP10623.1 - 3.6 7.9 22.4 1.2 9.4 6.7 4.1 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DASH_Duo1 PF08651.10 KFP10623.1 - 4.1 7.3 7.5 0.96 9.3 0.6 3.4 4 0 0 4 4 4 0 DASH complex subunit Duo1 DUF4140 PF13600.6 KFP10623.1 - 4.1 7.9 23.0 0.32 11.5 0.9 5.1 3 2 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) Syntaxin-6_N PF09177.11 KFP10623.1 - 4.2 8.0 14.5 6.4 7.4 4.3 4.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 KFP10623.1 - 4.5 7.8 13.3 5.7 7.5 0.4 4.1 3 2 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.11 KFP10623.1 - 5 7.4 28.7 1.7 8.9 1.4 4.8 3 2 1 4 4 4 0 Spc24 subunit of Ndc80 CRR7 PF12095.8 KFP10623.1 - 5.1 7.6 9.1 1.4 9.5 0.5 3.6 3 1 1 4 4 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1451 PF07295.11 KFP10623.1 - 5.1 7.1 16.4 1.1 9.3 1.8 3.1 2 1 1 3 3 3 0 Zinc-ribbon containing domain CHDCT2 PF08074.11 KFP10623.1 - 5.6 7.1 11.2 1.2 9.3 0.3 2.9 2 1 2 4 4 3 0 CHDCT2 (NUC038) domain V_ATPase_I PF01496.19 KFP10623.1 - 5.7 4.7 17.4 2.6 5.8 3.5 2.4 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family PRKG1_interact PF15898.5 KFP10623.1 - 5.9 7.9 26.1 1.2 10.1 0.6 4.1 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF883 PF05957.13 KFP10623.1 - 8.6 7.0 16.3 4.3 8.0 6.4 4.0 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.9 KFP10623.1 - 9 5.3 20.2 3.8 6.5 9.6 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAPEG PF01124.18 KFP10625.1 - 9.8e-16 57.8 1.0 1.2e-15 57.6 1.0 1.1 1 0 0 1 1 1 1 MAPEG family TPPK_C PF12555.8 KFP10625.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal MORN PF02493.20 KFP10626.1 - 4.2e-13 48.3 21.8 0.0015 18.3 0.9 6.7 7 0 0 7 7 7 4 MORN repeat SET PF00856.28 KFP10626.1 - 1.1e-06 29.1 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 SET domain MORN_2 PF07661.13 KFP10626.1 - 0.34 11.3 8.9 0.4 11.1 0.0 4.9 6 0 0 6 6 6 0 MORN repeat variant CD20 PF04103.15 KFP10627.1 - 2.4e-17 63.5 15.0 1.4e-16 61.0 15.0 1.9 1 1 0 1 1 1 1 CD20-like family DUF5518 PF17647.1 KFP10627.1 - 0.017 15.2 7.5 0.038 14.1 3.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5518) UPF0220 PF05255.11 KFP10627.1 - 0.048 13.2 1.8 0.074 12.6 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF2919 PF11143.8 KFP10627.1 - 0.17 12.2 1.2 0.41 11.0 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2919) NARP1 PF12569.8 KFP10628.1 - 3.6e-219 729.0 21.0 3.6e-219 729.0 21.0 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFP10628.1 - 1.7e-15 55.8 25.0 0.0005 20.0 0.1 9.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP10628.1 - 1.3e-13 50.5 7.8 0.039 14.8 0.0 9.2 7 3 3 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP10628.1 - 5.4e-12 46.1 19.7 0.0035 17.8 0.3 7.7 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP10628.1 - 4.3e-11 42.1 26.8 0.00037 20.5 0.1 8.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP10628.1 - 1.4e-10 41.6 7.1 0.1 13.3 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP10628.1 - 1.5e-09 37.2 25.2 0.0024 17.6 0.2 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP10628.1 - 5.3e-08 33.0 27.0 0.00067 19.8 0.8 6.3 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KFP10628.1 - 1.5e-07 30.9 9.5 0.00025 20.7 0.1 5.4 7 0 0 7 7 7 2 TPR repeat TPR_9 PF13371.6 KFP10628.1 - 2.7e-06 27.4 5.1 0.3 11.2 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP10628.1 - 3.8e-06 27.1 20.8 0.7 10.2 0.1 7.3 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFP10628.1 - 9.4e-05 22.7 0.1 5 8.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP10628.1 - 0.00069 19.5 14.7 1.1 9.4 0.1 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP10628.1 - 0.0011 18.2 3.2 0.0011 18.2 3.2 4.0 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP10628.1 - 0.0021 18.5 11.0 12 6.8 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFP10628.1 - 0.065 13.3 1.8 18 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat F-protein PF00469.20 KFP10628.1 - 0.19 11.3 4.3 0.22 11.1 2.5 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef MIT PF04212.18 KFP10628.1 - 0.47 10.6 12.4 1.8 8.7 0.1 6.5 7 2 2 9 9 7 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KFP10628.1 - 0.76 9.9 10.5 23 5.2 0.1 5.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFP10628.1 - 1.4 8.9 13.5 1.4e+02 2.5 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KFP10628.1 - 5.1 7.6 9.9 6.4 7.3 0.0 5.9 7 0 0 7 7 6 0 PPR repeat ETC_C1_NDUFA4 PF04800.12 KFP10630.1 - 1.2e-38 131.2 2.1 1.2e-38 131.2 2.1 1.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF1775 PF07987.11 KFP10630.1 - 0.013 15.7 0.7 2.8 8.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unkown function (DUF1775) DUF2188 PF09954.9 KFP10630.1 - 0.017 15.2 0.3 0.041 14.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Arf PF00025.21 KFP10631.1 - 1.3e-29 102.8 0.0 1.6e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP10631.1 - 4.9e-09 36.4 0.0 6.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP10631.1 - 1.1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFP10631.1 - 1.4e-06 28.0 0.0 1.5e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP10631.1 - 0.00018 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP10631.1 - 0.00076 18.7 0.8 0.066 12.4 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP10631.1 - 0.00085 19.4 0.0 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KFP10631.1 - 0.0024 18.3 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP10631.1 - 0.0091 16.4 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFP10631.1 - 0.012 15.7 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFP10631.1 - 0.013 15.1 0.0 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KFP10631.1 - 0.014 15.7 0.0 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP10631.1 - 0.019 15.5 0.3 0.17 12.4 0.3 2.0 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFP10631.1 - 0.022 14.7 0.1 0.34 10.8 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KFP10631.1 - 0.053 13.6 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP10631.1 - 0.059 12.9 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFP10631.1 - 0.096 12.4 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KFP10631.1 - 0.098 13.0 0.1 0.25 11.8 0.1 1.7 1 1 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KFP10631.1 - 0.1 12.4 0.0 4.6 6.9 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HSP20 PF00011.21 KFP10632.1 - 2.7e-15 56.3 0.1 5.7e-15 55.3 0.0 1.5 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFP10632.1 - 0.006 16.1 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HrpB1_HrpK PF09613.10 KFP10632.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) IGFBP PF00219.18 KFP10633.1 - 7.3e-09 36.2 20.8 7.3e-09 36.2 20.8 2.4 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Trypsin PF00089.26 KFP10634.1 - 1.1e-65 221.5 0.6 1.3e-65 221.4 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP10634.1 - 2.4e-06 28.5 0.0 3.9e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP10634.1 - 0.0054 17.1 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) WD40 PF00400.32 KFP10635.1 - 0.00022 21.9 0.8 0.18 12.7 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10635.1 - 0.001 19.3 0.0 0.88 9.9 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain GSHPx PF00255.19 KFP10636.1 - 2.2e-36 123.7 0.0 3e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFP10636.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family DUF1146 PF06612.11 KFP10636.1 - 0.055 13.5 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) rRNA_proc-arch PF13234.6 KFP10637.1 - 3.7e-88 296.0 1.8 6.5e-88 295.2 1.8 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFP10637.1 - 5.7e-59 198.5 0.8 1.2e-58 197.5 0.8 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KFP10637.1 - 1.1e-16 61.1 0.0 2.8e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP10637.1 - 1.7e-07 31.5 0.0 1.8e-06 28.2 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFP10637.1 - 0.027 14.7 0.0 0.19 12.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFP10637.1 - 0.051 13.9 0.1 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3379 PF11859.8 KFP10637.1 - 0.056 12.8 0.1 0.19 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) PAP2 PF01569.21 KFP10638.1 - 3.2e-28 98.2 1.7 3.2e-28 98.2 1.7 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFP10638.1 - 0.0074 16.8 2.8 0.0074 16.8 2.8 2.4 2 1 0 2 2 2 1 PAP2 superfamily C-terminal COX4 PF02936.14 KFP10638.1 - 0.029 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Aa_trans PF01490.18 KFP10639.1 - 3.9e-25 88.4 34.0 3.2e-15 55.8 7.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pox_A14 PF05767.12 KFP10639.1 - 0.38 10.9 0.0 0.38 10.9 0.0 3.2 4 1 1 5 5 5 0 Poxvirus virion envelope protein A14 DEAD PF00270.29 KFP10640.1 - 1.4e-49 168.3 0.0 2.3e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP10640.1 - 6.5e-32 110.2 0.1 1.2e-30 106.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP10640.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFP10640.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain fn3 PF00041.21 KFP10641.1 - 8e-24 83.8 6.8 1.9e-09 37.7 0.1 4.1 4 0 0 4 4 4 3 Fibronectin type III domain Big_5 PF13205.6 KFP10641.1 - 0.00074 20.2 3.3 0.015 16.0 0.2 2.5 2 0 0 2 2 2 2 Bacterial Ig-like domain Pur_ac_phosph_N PF16656.5 KFP10641.1 - 0.011 16.3 13.0 3.8 8.2 0.0 4.1 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Ank_2 PF12796.7 KFP10642.1 - 1.6e-42 144.0 5.9 4.7e-10 39.9 0.4 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10642.1 - 1.8e-34 117.6 7.2 8.7e-09 35.8 0.0 6.8 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP10642.1 - 5.1e-29 99.4 8.4 2.4e-05 24.5 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFP10642.1 - 8.2e-28 93.4 3.6 0.00068 19.9 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KFP10642.1 - 1.2e-27 95.5 7.9 2.1e-07 31.1 0.0 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Pkinase PF00069.25 KFP10643.1 - 2.7e-67 226.9 0.0 1.5e-66 224.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10643.1 - 3.9e-41 141.1 0.1 6.2e-40 137.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP10643.1 - 9.7e-09 34.9 0.3 0.00014 21.3 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFP10643.1 - 1.9e-06 26.9 0.5 6.5e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase zf-RING_2 PF13639.6 KFP10643.1 - 2e-05 24.8 11.8 2e-05 24.8 11.8 2.3 2 0 0 2 2 1 1 Ring finger domain SWIM PF04434.17 KFP10643.1 - 6.5e-05 22.5 0.2 0.00013 21.5 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 KFP10643.1 - 0.018 15.0 8.8 0.044 13.7 8.8 1.8 1 0 0 1 1 1 0 PHD-finger Phostensin_N PF13916.6 KFP10643.1 - 0.036 14.4 0.4 0.15 12.4 0.3 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal APH PF01636.23 KFP10643.1 - 0.037 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FANCL_C PF11793.8 KFP10643.1 - 0.11 12.7 7.7 0.34 11.1 7.7 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFP10643.1 - 0.2 11.7 4.7 0.52 10.4 4.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 KFP10643.1 - 0.55 10.6 5.8 4.2 7.8 2.1 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SET PF00856.28 KFP10644.1 - 0.00013 22.4 0.1 0.00022 21.6 0.1 1.6 1 1 0 1 1 1 1 SET domain ELM2 PF01448.24 KFP10645.1 - 4.9e-11 43.2 0.2 1.5e-10 41.7 0.2 1.8 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP10645.1 - 5e-06 26.6 0.1 1.1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP10645.1 - 0.0044 16.9 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Vasculin PF15337.6 KFP10646.1 - 1.6e-41 141.1 3.9 1.6e-41 141.1 3.9 2.6 2 1 1 3 3 3 1 Vascular protein family Vasculin-like 1 Neural_ProG_Cyt PF06567.11 KFP10646.1 - 0.075 13.3 3.5 0.32 11.2 3.5 2.2 1 1 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Pkinase PF00069.25 KFP10647.1 - 4.8e-69 232.7 0.0 7.5e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10647.1 - 1e-36 126.6 0.0 1.6e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KFP10647.1 - 4.9e-35 119.5 1.9 2.3e-16 59.7 0.5 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 KFP10647.1 - 4.3e-06 25.8 0.1 7.9e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP10647.1 - 0.00089 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like 7tm_4 PF13853.6 KFP10648.1 - 3.7e-35 122.0 4.8 4.1e-35 121.9 4.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP10648.1 - 3.2e-14 52.9 6.6 4.4e-14 52.4 6.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP10648.1 - 0.037 13.4 2.8 0.091 12.1 2.8 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP10649.1 - 2.9e-43 148.6 15.5 3.5e-43 148.3 15.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP10649.1 - 1.1e-27 97.0 16.8 1.5e-27 96.6 16.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP10649.1 - 7.4e-05 22.2 13.2 0.00012 21.6 13.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP10649.1 - 0.016 14.8 13.3 0.045 13.4 13.3 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TMEMspv1-c74-12 PF11044.8 KFP10649.1 - 2.5 8.2 6.3 0.17 11.9 0.6 1.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sugar_tr PF00083.24 KFP10650.1 - 9.4e-158 525.8 24.3 1.2e-157 525.5 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP10650.1 - 1.3e-19 70.3 32.7 6.6e-18 64.7 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFP10650.1 - 0.14 10.5 8.3 0.016 13.7 3.2 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pox_EPC_I2-L1 PF12575.8 KFP10650.1 - 0.22 11.8 3.0 0.97 9.7 3.0 2.2 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF2127 PF09900.9 KFP10650.1 - 0.4 10.9 5.1 0.089 13.0 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) Phage_holin_3_2 PF04550.12 KFP10650.1 - 8.6 7.0 9.6 1.9 9.1 3.3 2.9 2 0 0 2 2 2 0 Phage holin family 2 TPR_12 PF13424.6 KFP10651.1 - 2.4e-15 56.6 9.8 0.00032 20.9 0.8 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP10651.1 - 1e-05 25.2 10.0 0.14 12.3 0.2 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP10651.1 - 1.4e-05 24.7 3.8 0.00033 20.1 0.6 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KFP10651.1 - 0.00077 19.3 3.4 0.66 9.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP10651.1 - 0.034 14.8 3.0 13 6.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP10651.1 - 0.039 13.8 5.9 46 4.1 0.7 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP10651.1 - 0.072 13.3 7.0 4.8 7.6 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP10651.1 - 1.9 9.1 6.6 13 6.4 0.1 3.7 2 2 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP10651.1 - 5.7 7.7 12.7 3 8.6 0.7 4.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFP10651.1 - 9.1 7.2 13.6 26 5.8 1.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4686 PF15742.5 KFP10652.1 - 6.2e-89 298.8 99.0 2.4e-87 293.6 97.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4686) CD34_antigen PF06365.12 KFP10653.1 - 5.2e-05 22.9 0.2 6.7e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 KFP10653.1 - 0.006 16.5 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family MSA-2c PF12238.8 KFP10653.1 - 0.0079 16.2 0.1 0.0081 16.2 0.1 1.1 1 0 0 1 1 1 1 Merozoite surface antigen 2c LapA_dom PF06305.11 KFP10653.1 - 0.0093 15.8 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain 7tm_1 PF00001.21 KFP10653.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4834 PF16118.5 KFP10653.1 - 0.016 16.2 0.0 0.023 15.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3169 PF11368.8 KFP10653.1 - 0.022 14.3 0.0 0.028 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) TssO PF17561.2 KFP10653.1 - 0.025 14.7 0.7 0.034 14.3 0.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO OSTbeta PF15048.6 KFP10653.1 - 0.029 14.5 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein OAD_gamma PF04277.13 KFP10653.1 - 0.031 14.9 0.0 0.082 13.5 0.0 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3328 PF11807.8 KFP10653.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2663 PF10864.8 KFP10653.1 - 0.041 14.3 0.2 0.054 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Tmemb_9 PF05434.11 KFP10653.1 - 0.042 13.7 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 TMEM9 EphA2_TM PF14575.6 KFP10653.1 - 0.043 14.7 0.0 0.063 14.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KFP10653.1 - 0.061 13.2 0.3 0.083 12.7 0.3 1.2 1 1 0 1 1 1 0 Transmembrane protein 51 ATP-synt_8 PF00895.20 KFP10653.1 - 0.11 13.0 0.3 0.22 12.0 0.3 1.5 1 0 0 1 1 1 0 ATP synthase protein 8 Afaf PF15339.6 KFP10653.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2207 PF09972.9 KFP10653.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Brr6_like_C_C PF10104.9 KFP10653.1 - 0.96 9.2 6.0 1.2 8.9 4.6 1.7 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain RNase_Zc3h12a PF11977.8 KFP10656.1 - 2.1e-66 222.5 0.0 2.8e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP10656.1 - 2.4e-20 72.2 1.9 4.5e-20 71.3 1.9 1.5 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFP10656.1 - 9.9e-05 22.1 7.0 0.00017 21.3 7.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Omega-toxin PF06357.11 KFP10656.1 - 0.011 15.5 4.8 0.021 14.6 4.8 1.3 1 0 0 1 1 1 0 Omega-atracotoxin PRORP PF16953.5 KFP10656.1 - 0.068 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 KFP10656.1 - 1.1 9.8 9.6 2.6 8.7 9.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFP10656.1 - 1.2 9.2 8.3 9 6.3 8.3 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RHH_7 PF16777.5 KFP10657.1 - 0.0068 16.8 0.2 0.027 14.9 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulator, RHH-like, CopG RhoGAP PF00620.27 KFP10658.1 - 2.6e-40 137.7 0.0 3.3e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 KFP10658.1 - 5.4e-07 29.9 0.1 3.9e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 DUF2183 PF09949.9 KFP10658.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) RA PF00788.23 KFP10659.1 - 3.5e-13 50.0 0.0 1.2e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IQ_SEC7_PH PF16453.5 KFP10659.1 - 0.004 17.1 0.2 0.021 14.8 0.1 2.2 2 1 1 3 3 3 1 PH domain Ras_bdg_2 PF14847.6 KFP10659.1 - 0.029 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PH_16 PF17838.1 KFP10659.1 - 0.063 13.1 0.8 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 PH domain TUDOR PF00567.24 KFP10662.1 - 6.3e-91 300.7 10.8 7.8e-21 74.4 0.1 7.8 7 1 0 7 7 7 5 Tudor domain Agenet PF05641.12 KFP10662.1 - 1.5e-10 41.4 1.3 0.23 12.0 0.0 5.6 5 0 0 5 5 5 3 Agenet domain Tudor-knot PF11717.8 KFP10662.1 - 0.0047 16.8 1.0 6 6.9 0.0 4.2 5 0 0 5 5 5 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFP10662.1 - 0.011 15.3 0.4 1.1 9.0 0.0 3.3 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain FtsK_SpoIIIE PF01580.18 KFP10662.1 - 0.19 11.1 0.1 0.4 10.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Tcp10_C PF07202.13 KFP10664.1 - 3e-86 287.8 7.7 3.3e-86 287.7 6.9 1.4 1 1 0 1 1 1 1 T-complex protein 10 C-terminus DUF4520 PF15016.6 KFP10664.1 - 0.00056 19.9 0.0 0.7 10.0 0.1 3.7 1 1 3 4 4 4 1 Domain of unknown function (DUF4520) MORN_2 PF07661.13 KFP10664.1 - 0.001 19.0 3.1 1e+02 3.7 0.0 6.8 7 1 1 8 8 8 0 MORN repeat variant Plant_vir_prot PF01307.17 KFP10664.1 - 0.0061 16.8 0.2 2.6 8.3 0.0 2.7 1 1 2 3 3 3 2 Plant viral movement protein PepSY_like PF11396.8 KFP10664.1 - 0.048 14.2 0.9 0.27 11.8 0.2 2.5 1 1 2 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like SH3_15 PF18346.1 KFP10664.1 - 0.048 14.0 1.0 13 6.2 0.0 3.7 2 2 1 3 3 3 0 Mind bomb SH3 repeat domain Ank_2 PF12796.7 KFP10665.1 - 1.1e-19 70.8 1.2 9.8e-11 42.1 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP10665.1 - 1.2e-18 66.9 0.2 1.2e-09 38.2 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP10665.1 - 7.1e-17 61.5 0.5 1.3e-06 28.9 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP10665.1 - 6e-13 47.7 0.6 4.2e-05 23.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFP10665.1 - 1.6e-09 37.8 0.7 0.00032 21.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Chromo PF00385.24 KFP10665.1 - 2.5e-09 36.9 0.7 9.9e-09 35.0 0.7 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-FCS PF06467.14 KFP10667.1 - 9.1e-68 223.9 116.3 5.4e-10 39.1 3.9 10.6 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.8 KFP10667.1 - 6.2e-63 211.6 1.5 1.8e-62 210.1 1.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Arc_trans_TRASH PF08394.10 KFP10667.1 - 0.00035 20.8 4.6 0.00035 20.8 4.6 7.8 10 0 0 10 10 10 1 Archaeal TRASH domain YHS PF04945.13 KFP10667.1 - 0.00044 20.3 3.1 0.0046 17.0 0.2 9.5 10 0 0 10 10 10 3 YHS domain NosL PF05573.12 KFP10667.1 - 0.051 13.9 4.9 6.8 7.0 0.0 4.0 3 1 1 4 4 4 0 NosL Ribosomal_L24e PF01246.20 KFP10667.1 - 4.3 7.6 31.5 0.056 13.7 0.5 6.8 5 1 1 6 6 6 0 Ribosomal protein L24e Connexin PF00029.19 KFP10669.1 - 1e-86 290.5 11.4 6.7e-85 284.6 11.4 2.0 1 1 0 1 1 1 1 Connexin Connexin PF00029.19 KFP10670.1 - 2.1e-87 292.7 12.3 2.1e-87 292.7 12.3 2.5 2 1 0 2 2 2 1 Connexin Sema PF01403.19 KFP10673.1 - 5e-57 193.6 0.0 6.5e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Sema domain ATP-grasp_2 PF08442.10 KFP10675.1 - 1.4e-76 256.6 1.6 2.6e-76 255.7 1.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFP10675.1 - 2.3e-28 98.9 0.2 5e-28 97.9 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFP10675.1 - 2.2e-10 40.4 0.5 4.9e-10 39.3 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFP10675.1 - 0.00096 19.0 0.1 0.0022 17.8 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF4462 PF14692.6 KFP10676.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) MFS_1 PF07690.16 KFP10678.1 - 1.8e-44 152.1 21.5 7.7e-38 130.3 24.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP10678.1 - 1.8e-08 33.7 2.0 0.0083 15.0 0.0 3.8 1 1 1 3 3 3 3 MFS_1 like family BACK PF07707.15 KFP10679.1 - 6.1e-32 109.8 1.5 5.2e-31 106.8 0.5 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KFP10679.1 - 5.3e-30 102.7 11.2 2.4e-11 43.0 1.0 5.5 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 KFP10679.1 - 1.2e-28 99.5 0.2 3.5e-28 98.1 0.3 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 KFP10679.1 - 9.1e-21 73.4 6.1 4.2e-05 23.7 0.1 5.9 4 2 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KFP10679.1 - 3.9e-12 45.6 6.3 7.6e-06 25.7 0.3 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KFP10679.1 - 5.5e-11 42.3 0.6 0.0064 16.5 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP10679.1 - 8.1e-10 38.8 1.1 0.0026 18.0 0.0 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain DUF3342 PF11822.8 KFP10679.1 - 0.008 16.4 1.4 0.047 13.9 0.0 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3342) DUF4262 PF14081.6 KFP10679.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Kelch_5 PF13854.6 KFP10679.1 - 0.42 10.7 5.0 40 4.4 0.0 4.1 4 0 0 4 4 4 0 Kelch motif LRR_8 PF13855.6 KFP10680.1 - 5.6e-86 282.3 71.3 2.2e-15 56.1 5.2 7.6 3 2 6 9 9 9 9 Leucine rich repeat I-set PF07679.16 KFP10680.1 - 4.8e-53 177.2 0.0 3.6e-21 75.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP10680.1 - 3.6e-48 162.1 0.0 4.1e-17 62.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain LRR_4 PF12799.7 KFP10680.1 - 1.1e-37 127.5 47.5 3.8e-05 24.0 0.0 9.3 4 2 5 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 KFP10680.1 - 3.4e-34 117.0 0.0 6.1e-12 45.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP10680.1 - 3.3e-31 107.3 0.0 5.8e-12 45.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.6 KFP10680.1 - 7.2e-29 100.3 0.0 3.1e-09 36.9 0.0 3.9 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP10680.1 - 1.1e-18 67.4 6.3 0.00014 21.5 0.1 5.4 1 1 4 5 5 5 5 Leucine-rich repeat V-set PF07686.17 KFP10680.1 - 8.6e-18 64.5 2.1 7e-05 23.0 0.0 5.6 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP10680.1 - 5.3e-11 42.4 0.0 0.00056 19.9 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_1 PF00560.33 KFP10680.1 - 5.4e-09 35.4 33.4 7.9 7.5 0.1 13.9 15 0 0 15 15 15 1 Leucine Rich Repeat Ig_5 PF16681.5 KFP10680.1 - 1.8e-07 31.4 0.0 0.11 13.0 0.0 4.0 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP10680.1 - 4.2e-06 26.2 0.0 0.74 9.4 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP10680.1 - 1.7e-05 24.8 1.5 0.55 10.3 0.0 4.0 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP10680.1 - 0.00058 19.8 0.0 2 8.5 0.0 3.1 3 0 0 3 3 3 2 C17orf99 Ig domain LRRCT PF01463.24 KFP10680.1 - 0.0011 19.4 0.0 0.0053 17.2 0.0 2.3 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Ig_4 PF16680.5 KFP10680.1 - 0.0019 18.4 0.0 0.29 11.4 0.0 3.6 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KFP10680.1 - 0.019 15.2 0.0 0.99 9.6 0.0 2.9 3 0 0 3 3 2 0 Natural killer cell receptor 2B4 C2-set PF05790.15 KFP10680.1 - 0.023 14.9 0.0 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF2201 PF09967.9 KFP10680.1 - 0.031 14.4 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 VWA-like domain (DUF2201) LRR_6 PF13516.6 KFP10680.1 - 0.31 11.2 0.1 0.31 11.2 0.1 13.0 15 0 0 15 15 15 0 Leucine Rich repeat TPKR_C2 PF16920.5 KFP10680.1 - 8.5 6.6 6.4 57 4.0 2.7 3.4 3 0 0 3 3 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Mito_carr PF00153.27 KFP10681.1 - 3.9e-51 171.0 6.2 2.1e-21 75.6 0.6 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KFP10681.1 - 0.057 12.6 2.1 0.56 9.3 0.0 2.6 2 1 0 3 3 3 0 Gammaproteobacterial serine protease zf-HC5HC2H PF13771.6 KFP10682.1 - 1.7e-15 57.0 4.7 1.7e-15 57.0 4.7 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP10682.1 - 1.2e-10 41.6 5.3 1.2e-10 41.6 5.3 2.9 2 1 1 3 3 3 2 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KFP10682.1 - 0.00015 22.1 11.3 0.00015 22.1 11.3 4.2 4 2 0 4 4 4 2 Ring finger domain zf-RING_11 PF17123.5 KFP10682.1 - 0.0041 16.8 3.0 0.0041 16.8 3.0 3.2 2 0 0 2 2 2 1 RING-like zinc finger PhnA_Zn_Ribbon PF08274.12 KFP10682.1 - 0.39 10.7 15.9 1.2 9.1 0.2 4.6 3 1 1 4 4 4 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 KFP10682.1 - 1 9.4 10.3 3 7.8 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_4 PF14570.6 KFP10682.1 - 2.8 7.8 18.7 0.36 10.7 1.0 4.7 5 0 0 5 5 5 0 RING/Ubox like zinc-binding domain RPN7 PF10602.9 KFP10686.1 - 9.6e-63 211.0 2.4 1.4e-62 210.5 2.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFP10686.1 - 3.5e-18 66.0 0.2 9.5e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPW8 PF05659.11 KFP10686.1 - 0.0068 16.1 2.6 0.53 10.0 0.3 3.2 3 0 0 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF1732 PF08340.11 KFP10686.1 - 0.042 13.8 1.8 5.7 7.0 0.6 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1732) SCA7 PF08313.12 KFP10687.1 - 5.4e-26 90.3 1.9 5.4e-26 90.3 1.9 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain OrsD PF12013.8 KFP10687.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.8 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D THOC7 PF05615.13 KFP10689.1 - 3.1e-38 131.0 9.4 4.6e-38 130.5 0.8 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 UPF0193 PF05250.11 KFP10689.1 - 0.0012 18.7 3.9 0.0012 18.7 3.9 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) PMEI PF04043.15 KFP10689.1 - 0.13 12.6 0.7 0.24 11.8 0.2 1.6 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DASH_Dad2 PF08654.10 KFP10689.1 - 0.21 12.0 8.0 0.41 11.1 6.8 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad2 COG2 PF06148.11 KFP10689.1 - 0.22 11.6 11.0 0.052 13.6 1.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KFP10689.1 - 0.36 9.7 18.6 0.072 12.0 3.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 KFP10689.1 - 3 8.4 13.8 0.19 12.2 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 EP400_N PF15790.5 KFP10689.1 - 3.3 6.5 6.9 4.1 6.1 6.9 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal AATF-Che1 PF13339.6 KFP10689.1 - 3.7 8.2 13.6 2.3 8.9 6.2 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.6 KFP10689.1 - 4.1 6.7 8.5 0.19 11.0 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Med9 PF07544.13 KFP10689.1 - 4.2 7.5 19.3 2.1 8.5 4.9 3.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 KFP10689.1 - 4.8 5.0 13.1 5.8 4.7 13.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KFP10689.1 - 5.7 7.0 9.4 13 5.9 4.5 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) EF-hand_7 PF13499.6 KFP10690.1 - 0.00053 20.4 0.0 0.0009 19.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP10690.1 - 0.0017 18.2 0.0 0.076 12.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair S_100 PF01023.19 KFP10690.1 - 0.0034 17.0 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain MARVEL PF01284.23 KFP10691.1 - 1.1e-37 129.2 6.4 1.5e-37 128.9 6.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 KFP10691.1 - 0.001 18.8 1.2 0.0016 18.2 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) ECF_trnsprt PF12822.7 KFP10691.1 - 0.01 16.0 0.4 0.032 14.3 0.4 1.7 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Frizzled PF01534.17 KFP10691.1 - 0.014 14.5 0.4 0.014 14.5 0.4 2.0 1 1 0 2 2 2 0 Frizzled/Smoothened family membrane region DUF1129 PF06570.11 KFP10691.1 - 0.16 11.5 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3278 PF11683.8 KFP10691.1 - 0.17 11.9 1.6 0.46 10.6 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) DUF4570 PF15134.6 KFP10693.1 - 3.4e-31 107.5 5.8 7.3e-30 103.2 5.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4570) Angiomotin_C PF12240.8 KFP10693.1 - 0.0049 16.4 0.6 0.0064 16.1 0.6 1.1 1 0 0 1 1 1 1 Angiomotin C terminal CRR7 PF12095.8 KFP10693.1 - 0.07 13.6 0.3 0.13 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF667 PF05018.13 KFP10694.1 - 2e-36 125.4 0.0 3.2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) OCRE PF17780.1 KFP10694.1 - 0.015 15.4 0.2 0.033 14.2 0.2 1.6 1 0 0 1 1 1 0 OCRE domain Whirly PF08536.11 KFP10694.1 - 0.065 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Whirly transcription factor ILEI PF15711.5 KFP10695.1 - 1.4e-26 92.8 0.1 2.4e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Interleukin-like EMT inducer DUF1151 PF06625.11 KFP10696.1 - 2.1e-43 146.9 20.5 2.5e-43 146.6 20.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) TOPRIM_C PF16898.5 KFP10696.1 - 0.012 15.9 1.0 0.015 15.6 1.0 1.1 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Synaptobrevin PF00957.21 KFP10696.1 - 0.59 10.0 2.3 0.84 9.5 2.3 1.4 1 0 0 1 1 1 0 Synaptobrevin ACOX PF01756.19 KFP10697.1 - 5.4e-66 221.6 1.5 6.7e-64 214.8 0.3 2.3 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFP10697.1 - 2e-27 96.2 0.1 4.2e-27 95.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFP10697.1 - 1.4e-07 31.7 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFP10697.1 - 1.3e-05 25.4 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4313 PF14190.6 KFP10697.1 - 0.15 12.0 0.3 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) BTB_2 PF02214.22 KFP10698.1 - 7.6e-22 77.5 0.1 2e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFP10698.1 - 0.0004 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Transket_pyr PF02779.24 KFP10699.1 - 1.2e-44 152.1 0.0 2.7e-44 150.9 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFP10699.1 - 5.6e-34 116.7 0.0 9.6e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Hanta_G2 PF01561.16 KFP10699.1 - 0.11 11.1 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 MaoC_dehydratas PF01575.19 KFP10700.1 - 9.5e-19 67.2 0.0 1.2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KFP10700.1 - 4.7e-06 26.8 0.0 8.9e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KFP10700.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase superfamily RNase_P_Rpp14 PF01900.19 KFP10701.1 - 3.9e-06 27.0 0.0 4.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family cNMP_binding PF00027.29 KFP10702.1 - 2.2e-42 143.0 0.1 4.9e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Mito_carr PF00153.27 KFP10703.1 - 4.5e-61 202.8 0.1 5.6e-24 83.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein IBR PF01485.21 KFP10704.1 - 1.7e-20 73.0 45.3 8.3e-13 48.4 6.4 3.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFP10704.1 - 0.0012 18.6 6.2 0.0012 18.6 6.2 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP10704.1 - 0.0018 18.1 9.8 0.0018 18.1 9.8 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP10704.1 - 0.01 16.1 46.7 0.037 14.4 9.9 4.1 2 1 1 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 KFP10704.1 - 0.022 14.8 3.2 0.022 14.8 3.2 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP10704.1 - 0.026 14.7 4.9 0.026 14.7 4.9 4.5 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Fz PF01392.22 KFP10706.1 - 4.1e-27 95.0 4.8 4.1e-27 95.0 4.8 1.7 2 0 0 2 2 2 1 Fz domain 2OG-FeII_Oxy_3 PF13640.6 KFP10707.1 - 1.4e-14 54.8 0.1 3.5e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_7 PF13499.6 KFP10707.1 - 8e-09 35.8 0.0 2.9e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP10707.1 - 8.1e-08 31.3 0.0 0.0048 16.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP10707.1 - 3.8e-06 26.4 1.4 0.018 14.9 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP10707.1 - 2.2e-05 23.7 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP10707.1 - 0.00021 21.1 0.0 0.11 12.3 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFP10707.1 - 0.078 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain TruB_C PF09142.11 KFP10707.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal DALR_1 PF05746.15 KFP10708.1 - 1e-19 70.8 0.0 2.3e-19 69.7 0.0 1.6 1 1 0 1 1 1 1 DALR anticodon binding domain DUF3504 PF12012.8 KFP10709.1 - 2.4e-62 209.7 1.3 2.4e-62 209.7 1.3 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3504) CARD PF00619.21 KFP10709.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain PCNA_C PF02747.15 KFP10709.1 - 0.066 13.4 0.8 0.17 12.0 0.8 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain tRNA-synt_1c PF00749.21 KFP10710.1 - 2.4e-112 374.9 0.0 3.1e-112 374.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFP10710.1 - 3e-49 167.2 0.0 6.2e-49 166.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KFP10710.1 - 4.9e-30 104.3 1.6 8.4e-30 103.6 1.6 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SNF PF00209.18 KFP10711.1 - 3.1e-170 567.3 14.5 4.1e-170 566.9 14.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family CCDC71L PF15374.6 KFP10712.1 - 7.1e-176 585.3 19.3 8e-176 585.1 19.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L Kelch_1 PF01344.25 KFP10714.1 - 6.3e-38 128.1 1.0 4e-09 35.9 0.0 7.6 8 0 0 8 8 8 7 Kelch motif Kelch_6 PF13964.6 KFP10714.1 - 1.9e-26 91.4 5.0 2.5e-05 24.4 0.0 7.2 4 2 3 7 7 7 6 Kelch motif Kelch_3 PF13415.6 KFP10714.1 - 9.8e-22 76.7 2.1 2.9e-05 24.2 0.1 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP10714.1 - 5.6e-19 67.9 3.5 0.009 16.0 0.2 7.4 6 2 1 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP10714.1 - 1.8e-13 49.9 0.4 0.056 13.4 0.0 7.6 7 1 0 7 7 7 2 Kelch motif Kelch_5 PF13854.6 KFP10714.1 - 1.8e-09 37.4 0.4 0.0012 18.8 0.0 5.5 6 0 0 6 6 6 2 Kelch motif HEAT_PBS PF03130.16 KFP10714.1 - 1.1 10.1 3.5 4.1 8.4 0.0 3.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat IHO1 PF15771.5 KFP10715.1 - 1.1e-23 83.9 5.0 1.2e-23 83.7 5.0 1.0 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 Jagunal PF07086.12 KFP10716.1 - 4.2e-43 147.6 6.3 5.2e-43 147.3 6.3 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF3810 PF12725.7 KFP10716.1 - 0.15 11.3 1.9 0.18 11.1 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TTL PF03133.15 KFP10717.1 - 4.2e-60 203.4 0.0 1.1e-59 202.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ARPC4 PF05856.12 KFP10718.1 - 2.8e-45 153.9 3.6 3e-45 153.8 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Ada3 PF10198.9 KFP10719.1 - 3.3e-06 27.3 3.3 1.1e-05 25.6 3.3 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF4194 PF13835.6 KFP10719.1 - 0.12 12.1 2.1 0.29 10.9 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) Pkinase PF00069.25 KFP10720.1 - 3e-48 164.5 0.1 3.4e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10720.1 - 3.5e-27 95.3 0.1 4.1e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP10720.1 - 0.0002 20.8 0.1 0.00032 20.1 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP10720.1 - 0.00091 19.2 0.0 0.053 13.4 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KFP10720.1 - 0.0015 18.2 0.2 0.0019 17.8 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFP10720.1 - 0.0031 16.9 0.0 0.0084 15.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP10720.1 - 0.0055 15.5 0.0 0.0089 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP10720.1 - 0.011 15.4 0.1 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFP10720.1 - 0.03 13.8 0.1 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-HC5HC2H_2 PF13832.6 KFP10721.1 - 1.9e-37 127.8 7.4 1.9e-37 127.8 7.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFP10721.1 - 1e-34 120.2 8.8 1e-34 120.2 8.8 3.1 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFP10721.1 - 7.1e-26 90.3 6.1 7.1e-26 90.3 6.1 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFP10721.1 - 1.5e-22 79.4 1.0 3.5e-22 78.3 1.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KFP10721.1 - 1e-14 53.8 3.2 1e-14 53.8 3.2 2.9 2 1 1 3 3 3 1 PHD-finger PHD PF00628.29 KFP10721.1 - 1.2e-08 34.7 27.0 3.3e-07 30.1 12.5 2.9 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.17 KFP10721.1 - 1.5e-08 34.9 2.6 1.7e-08 34.7 0.0 2.6 2 0 0 2 2 2 1 PWWP domain BAG PF02179.16 KFP10721.1 - 5.8 7.4 10.1 0.62 10.5 3.8 2.4 2 0 0 2 2 2 0 BAG domain C1_2 PF03107.16 KFP10721.1 - 8.4 6.8 23.6 3 8.2 5.0 3.1 3 0 0 3 3 3 0 C1 domain Copine PF07002.16 KFP10722.1 - 1.4e-86 289.5 0.0 1.8e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP10722.1 - 1.9e-28 98.8 0.2 2.6e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP10722.1 - 7.3e-07 29.5 0.0 1.8e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 vWA found in TerF C terminus VCBS PF13517.6 KFP10722.1 - 0.011 16.4 0.4 0.049 14.2 0.4 2.2 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Myotub-related PF06602.14 KFP10723.1 - 0.00035 19.6 0.5 0.00082 18.4 0.5 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KFP10723.1 - 0.0004 20.4 0.0 0.00068 19.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFP10723.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KFP10723.1 - 0.17 11.7 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain L_HMGIC_fpl PF10242.9 KFP10724.1 - 1.8e-37 129.3 7.0 2e-37 129.1 7.0 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 KFP10724.1 - 0.034 14.0 1.1 0.048 13.5 1.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SLATT_fungal PF18142.1 KFP10724.1 - 0.054 13.5 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Atthog PF18800.1 KFP10724.1 - 0.071 13.0 1.7 0.09 12.7 1.7 1.2 1 0 0 1 1 1 0 Attenuator of Hedgehog Claudin_2 PF13903.6 KFP10724.1 - 0.078 12.7 1.8 0.098 12.4 1.8 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.9 KFP10724.1 - 0.13 11.0 0.2 0.14 10.9 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SET PF00856.28 KFP10725.1 - 2.5e-07 31.3 0.1 2.5e-07 31.3 0.1 3.1 3 1 0 3 3 3 1 SET domain Pkinase PF00069.25 KFP10726.1 - 7.2e-38 130.5 0.0 2e-37 129.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10726.1 - 3e-14 53.0 0.0 1.4e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP10726.1 - 0.0084 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KFP10726.1 - 0.084 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KFP10726.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Plexin_cytopl PF08337.12 KFP10727.1 - 1e-232 773.7 0.0 1.4e-232 773.3 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFP10727.1 - 1.4e-58 198.8 0.0 1.9e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Sema domain TIG PF01833.24 KFP10727.1 - 2.1e-33 114.3 1.9 8.9e-11 41.7 0.9 6.5 6 1 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 KFP10727.1 - 1.7e-24 86.2 0.4 1.7e-22 79.9 0.2 3.1 3 0 0 3 3 3 1 TIG domain found in plexin TIG_plexin PF17960.1 KFP10727.1 - 3.2e-20 71.9 3.6 1.4e-19 69.8 0.0 3.5 4 0 0 4 4 4 1 TIG domain PSI PF01437.25 KFP10727.1 - 8.1e-18 64.7 45.1 1.9e-09 37.9 13.7 3.6 3 0 0 3 3 3 3 Plexin repeat Laminin_II PF06009.12 KFP10728.1 - 0.052 13.6 8.4 4.1 7.4 5.3 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF2730 PF10805.8 KFP10728.1 - 0.79 9.9 4.1 0.87 9.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) CorA PF01544.18 KFP10728.1 - 2.8 7.2 8.8 4.7 6.4 1.2 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4078 PF13300.6 KFP10729.1 - 2.5e-27 95.0 11.0 2.5e-27 95.0 11.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Abhydrolase_1 PF00561.20 KFP10730.1 - 1.2e-07 31.6 0.1 4.9e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP10730.1 - 5.3e-07 30.5 0.1 6.3e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP10730.1 - 4.5e-05 22.8 0.0 0.00027 20.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFP10730.1 - 0.0058 15.7 0.0 0.0081 15.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Adaptin_N PF01602.20 KFP10731.1 - 3.2e-137 458.3 9.3 3.9e-137 458.0 9.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFP10731.1 - 2.3e-62 209.6 0.1 5.2e-62 208.5 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFP10731.1 - 2.6e-40 137.1 0.0 6.9e-40 135.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFP10731.1 - 8.6e-17 61.3 0.2 8.3e-09 35.7 0.0 5.2 3 2 4 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KFP10731.1 - 1.1e-10 41.9 14.5 0.002 18.2 0.5 4.9 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP10731.1 - 2e-08 34.6 3.8 0.00044 20.7 0.3 4.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFP10731.1 - 7.1e-06 25.8 7.2 0.49 10.8 0.1 6.2 6 0 0 6 6 6 2 HEAT repeat MOR2-PAG1_C PF14225.6 KFP10731.1 - 0.012 15.5 0.1 0.042 13.7 0.1 1.9 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HEAT_PBS PF03130.16 KFP10731.1 - 0.046 14.4 1.7 2.9 8.8 0.1 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KFP10731.1 - 0.056 13.4 3.3 0.31 11.0 0.3 3.4 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central Cnd3 PF12719.7 KFP10731.1 - 0.072 12.3 3.8 2.2 7.4 0.0 3.2 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain UvrD_C PF13361.6 KFP10732.1 - 1.1e-14 54.6 0.5 2.9e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KFP10732.1 - 2.3e-13 50.4 3.5 5e-08 32.8 3.5 2.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KFP10732.1 - 4.8e-13 49.7 0.0 1.2e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain F-box-like PF12937.7 KFP10732.1 - 3.3e-11 42.9 1.0 1.6e-10 40.7 1.0 2.2 2 0 0 2 2 2 1 F-box-like UvrD_C_2 PF13538.6 KFP10732.1 - 1.8e-10 40.4 0.4 2.5e-09 36.8 0.4 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain F-box PF00646.33 KFP10732.1 - 3.2e-10 39.6 0.6 1.1e-09 37.9 0.6 2.0 1 0 0 1 1 1 1 F-box domain Viral_helicase1 PF01443.18 KFP10732.1 - 2.6e-07 30.6 1.5 0.022 14.5 0.0 4.3 4 1 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KFP10732.1 - 1.1e-06 28.4 0.2 0.00034 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFP10732.1 - 3.2e-06 27.0 0.0 0.04 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KFP10732.1 - 0.0021 17.6 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KFP10732.1 - 0.014 15.2 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain F-box_4 PF15966.5 KFP10732.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box ResIII PF04851.15 KFP10732.1 - 0.053 13.5 1.6 0.12 12.3 1.6 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ank_2 PF12796.7 KFP10733.1 - 3.1e-58 194.3 8.8 4.4e-12 46.4 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10733.1 - 5.3e-58 192.7 13.6 8.8e-12 45.3 0.1 5.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP10733.1 - 1.6e-45 147.8 5.8 7.3e-05 22.9 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFP10733.1 - 2.5e-44 147.9 9.7 1.3e-06 28.5 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFP10733.1 - 9.8e-41 137.3 11.3 2.5e-08 34.0 0.0 8.3 2 1 7 9 9 9 9 Ankyrin repeats (many copies) DUF249 PF03158.13 KFP10733.1 - 0.051 13.3 0.1 5 6.8 0.0 3.1 3 1 0 3 3 3 0 Multigene family 530 protein GDI PF00996.18 KFP10734.1 - 2.8e-226 751.1 0.1 3.3e-226 750.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 KFP10734.1 - 0.035 14.2 1.9 3.3 7.8 0.3 3.0 2 1 0 2 2 2 0 Dda helicase SH3 domain Myc_N PF01056.18 KFP10734.1 - 0.041 13.8 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Amino_oxidase PF01593.24 KFP10734.1 - 0.057 12.7 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF3715 PF12509.8 KFP10735.1 - 5.3e-05 23.2 0.2 0.00012 22.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) DUF4462 PF14692.6 KFP10737.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ank_2 PF12796.7 KFP10738.1 - 4.8e-53 177.7 16.0 1.5e-15 57.5 3.2 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP10738.1 - 8.8e-40 134.6 9.1 2.1e-10 40.9 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP10738.1 - 6.1e-37 124.5 12.1 9.3e-07 29.0 0.1 7.1 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFP10738.1 - 5.3e-27 90.9 5.5 0.00015 22.0 0.0 7.0 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP10738.1 - 6e-25 87.0 4.6 3e-06 27.4 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP10738.1 - 1.3e-09 38.3 0.6 2.1e-09 37.5 0.6 1.4 1 0 0 1 1 1 1 SOCS box RhoGEF PF00621.20 KFP10739.1 - 1e-36 126.9 0.0 1.7e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFP10739.1 - 1.4e-08 34.8 0.1 1.4e-07 31.4 0.1 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_5 PF15405.6 KFP10739.1 - 4.4e-08 33.3 0.2 2.7e-07 30.7 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP10739.1 - 3.7e-07 30.6 0.0 6.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KFP10739.1 - 0.0057 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 PH domain Tubulin PF00091.25 KFP10740.1 - 9.8e-68 228.2 0.0 1.3e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP10740.1 - 3.4e-26 91.9 0.0 6.1e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP10740.1 - 0.00097 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain CRF PF00473.17 KFP10742.1 - 2.2e-14 53.2 3.3 9.1e-14 51.2 1.3 2.3 2 0 0 2 2 2 1 Corticotropin-releasing factor family Phage_clamp_A PF16790.5 KFP10742.1 - 0.029 14.8 0.1 0.04 14.4 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit UAA PF08449.11 KFP10743.1 - 9.5e-106 353.4 21.8 1.1e-105 353.2 21.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KFP10743.1 - 4.5e-05 23.0 15.4 0.00014 21.3 4.7 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KFP10743.1 - 0.092 12.9 30.4 0.14 12.3 14.8 2.9 2 1 0 2 2 2 0 EamA-like transporter family Guanylate_kin PF00625.21 KFP10744.1 - 1.5e-24 86.7 0.0 2.9e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.7 KFP10744.1 - 2.8e-21 75.3 32.0 1.7e-06 28.3 2.4 5.6 3 2 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP10744.1 - 2.2e-16 59.9 10.2 5.5e-14 52.0 3.1 3.0 1 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFP10744.1 - 1.8e-14 53.2 32.0 0.00017 21.3 8.6 5.3 2 1 3 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 KFP10744.1 - 2e-07 30.5 23.3 0.44 10.7 0.1 7.4 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 KFP10744.1 - 0.041 14.4 19.1 61 4.8 2.8 7.4 5 3 0 5 5 5 0 Leucine Rich Repeat Sec8_exocyst PF04048.14 KFP10748.1 - 3.7e-19 69.0 4.1 5.1e-19 68.6 1.4 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Zw10 PF06248.13 KFP10748.1 - 5.5e-06 25.2 7.4 5.5e-06 25.2 7.4 2.0 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 KFP10748.1 - 0.00031 20.1 6.6 0.00031 20.1 6.6 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 KFP10748.1 - 0.0016 18.6 2.4 0.0016 18.6 2.4 3.3 2 1 2 4 4 4 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KFP10748.1 - 0.011 14.5 11.3 0.014 14.1 6.8 2.1 2 0 0 2 2 2 0 Dor1-like family EzrA PF06160.12 KFP10748.1 - 0.02 13.1 7.0 0.019 13.2 3.0 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_14 PF13173.6 KFP10748.1 - 0.061 13.4 0.8 0.66 10.0 0.1 2.6 1 1 2 3 3 3 0 AAA domain PEP-utilisers_N PF05524.13 KFP10748.1 - 0.089 13.0 0.6 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal T3SS_needle_E PF08988.10 KFP10748.1 - 0.095 12.9 2.1 2.3 8.4 0.2 3.1 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Ead_Ea22 PF13935.6 KFP10748.1 - 0.13 12.9 3.5 0.44 11.2 1.3 2.6 2 1 1 3 3 3 0 Ead/Ea22-like protein Vps51 PF08700.11 KFP10748.1 - 0.56 10.3 7.9 1.7 8.7 1.3 2.9 3 0 0 3 3 3 0 Vps51/Vps67 DASH_Duo1 PF08651.10 KFP10748.1 - 0.75 9.6 6.7 2.2 8.1 0.5 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 ResIII PF04851.15 KFP10748.1 - 0.84 9.6 4.5 0.32 11.0 1.1 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit YojJ PF10372.9 KFP10748.1 - 0.89 9.7 4.8 1.4 9.1 0.1 3.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus 5_3_exonuc PF01367.20 KFP10748.1 - 2.6 8.7 6.1 25 5.6 0.0 3.6 3 1 1 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold Prominin PF05478.11 KFP10748.1 - 4.1 5.2 12.3 2.5 5.9 5.4 2.0 1 1 1 2 2 2 0 Prominin Exonuc_VII_L PF02601.15 KFP10748.1 - 5.3 6.5 9.5 49 3.3 9.5 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF737 PF05300.11 KFP10749.1 - 1.5e-36 126.7 26.7 1.5e-36 126.7 26.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF737) CHCH PF06747.13 KFP10749.1 - 0.0029 17.7 2.2 0.0056 16.8 2.2 1.5 1 0 0 1 1 1 1 CHCH domain DNA_photolyase PF00875.18 KFP10749.1 - 0.32 11.0 5.8 0.13 12.2 3.3 1.6 1 1 0 1 1 1 0 DNA photolyase ECH_2 PF16113.5 KFP10749.1 - 0.62 9.5 5.0 0.71 9.3 5.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Exonuc_VII_L PF02601.15 KFP10749.1 - 0.94 9.0 13.5 1.2 8.7 13.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit C_GCAxxG_C_C PF09719.10 KFP10749.1 - 1.1 9.6 4.0 1.7 9.0 4.0 1.7 1 1 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Jnk-SapK_ap_N PF09744.9 KFP10749.1 - 1.8 8.8 23.6 4 7.6 23.6 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ZnuA PF01297.17 KFP10749.1 - 4.1 6.7 5.8 11 5.3 5.7 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF2570 PF10828.8 KFP10749.1 - 7 6.5 12.9 0.22 11.4 3.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) Sema PF01403.19 KFP10753.1 - 5.1e-62 210.1 0.0 6.2e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.12 KFP10756.1 - 1.6e-262 872.1 2.7 2e-262 871.8 2.7 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFP10756.1 - 7.2e-44 147.8 5.0 1.4e-13 50.7 0.1 6.1 6 0 0 6 6 6 4 IPT/TIG domain TIG_2 PF18020.1 KFP10756.1 - 2.8e-35 120.8 0.4 3.9e-34 117.2 0.1 2.8 2 0 0 2 2 2 1 TIG domain found in plexin PSI PF01437.25 KFP10756.1 - 5.7e-23 81.2 56.9 1.9e-10 41.1 15.3 3.6 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 KFP10756.1 - 6.4e-22 77.4 10.6 1.3e-20 73.2 0.1 5.1 6 0 0 6 6 6 2 TIG domain PSI_integrin PF17205.3 KFP10756.1 - 0.00067 19.3 49.7 0.0012 18.6 13.8 3.6 3 0 0 3 3 3 3 Integrin plexin domain RasGAP PF00616.19 KFP10756.1 - 0.0022 17.7 1.0 0.46 10.2 0.9 2.7 2 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase Muskelin_N PF06588.11 KFP10759.1 - 6e-89 297.2 0.3 9.4e-89 296.6 0.3 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 KFP10759.1 - 2.6e-21 75.4 4.8 2.7e-10 40.3 0.0 5.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KFP10759.1 - 6.1e-18 64.1 18.5 1.4e-06 27.7 0.3 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KFP10759.1 - 4.2e-16 58.6 5.4 0.0053 17.0 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFP10759.1 - 3.3e-15 55.8 9.3 5.8e-05 23.0 0.1 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP10759.1 - 1.1e-14 54.0 11.8 0.00032 20.6 0.2 6.6 6 1 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.25 KFP10759.1 - 2.4e-07 30.9 0.0 5.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.15 KFP10759.1 - 1.4e-05 24.9 12.3 0.1 12.6 0.1 6.1 6 1 1 7 7 7 2 Kelch motif Sad1_UNC PF07738.13 KFP10759.1 - 0.029 14.4 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Endonuclease_NS PF01223.23 KFP10760.1 - 8.5e-31 107.5 2.6 4.1e-30 105.3 2.6 1.8 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KFP10760.1 - 0.01 15.9 2.0 0.023 14.8 1.7 1.8 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Sushi PF00084.20 KFP10761.1 - 1.1e-08 35.5 1.4 1.3e-08 35.3 1.4 1.1 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) G-patch PF01585.23 KFP10762.1 - 3.4e-13 49.3 1.5 7.6e-13 48.1 1.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KFP10762.1 - 5.3e-05 23.0 0.1 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.11 KFP10762.1 - 2.7 6.7 5.4 3.6 6.3 5.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KFP10762.1 - 8.9 4.5 6.7 13 3.9 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein 6PF2K PF01591.18 KFP10763.1 - 6.9e-103 342.7 0.4 1.1e-102 342.0 0.4 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFP10763.1 - 2.8e-43 147.9 0.0 4e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFP10763.1 - 2.1e-07 31.2 0.0 5.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFP10763.1 - 0.00084 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KFP10763.1 - 0.036 14.5 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 KFP10763.1 - 0.051 12.9 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Arf PF00025.21 KFP10763.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family HMG_box_2 PF09011.10 KFP10763.1 - 0.3 11.7 1.4 2.6 8.7 0.3 2.4 2 0 0 2 2 2 0 HMG-box domain Pkinase PF00069.25 KFP10764.1 - 3.9e-42 144.4 0.0 6.9e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KFP10764.1 - 2.3e-32 110.7 22.1 3.2e-17 62.2 6.7 2.9 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 KFP10764.1 - 1.4e-26 93.3 2.3 1.7e-26 93.0 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase C1_2 PF03107.16 KFP10764.1 - 0.00011 22.4 17.1 0.026 14.8 5.9 2.8 2 0 0 2 2 2 2 C1 domain zf-RING_9 PF13901.6 KFP10764.1 - 0.00015 21.8 16.1 0.0015 18.6 5.7 2.5 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KFP10764.1 - 0.005 16.9 2.5 0.005 16.9 2.5 2.5 2 0 0 2 2 2 1 KIAA1045 RING finger PHD PF00628.29 KFP10764.1 - 0.0083 16.0 21.1 0.087 12.7 6.6 2.9 2 0 0 2 2 2 2 PHD-finger Haspin_kinase PF12330.8 KFP10764.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFP10764.1 - 0.024 13.9 0.1 0.72 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KFP10764.1 - 0.039 13.9 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING-like PF08746.11 KFP10764.1 - 0.07 13.4 23.8 0.13 12.6 8.1 3.0 2 0 0 2 2 2 0 RING-like domain DUF2318 PF10080.9 KFP10764.1 - 0.094 12.8 10.9 0.046 13.8 1.3 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) PHD_2 PF13831.6 KFP10764.1 - 0.32 10.6 11.4 1 9.0 1.9 3.0 2 0 0 2 2 2 0 PHD-finger DZR PF12773.7 KFP10764.1 - 0.4 10.7 19.7 0.037 14.0 3.1 3.0 3 0 0 3 3 2 0 Double zinc ribbon FYVE PF01363.21 KFP10764.1 - 1 9.6 14.3 3.2 8.0 2.7 2.6 2 0 0 2 2 2 0 FYVE zinc finger GFA PF04828.14 KFP10764.1 - 2.6 8.4 11.8 0.16 12.3 0.6 3.7 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf-ACC PF17848.1 KFP10764.1 - 3.2 7.9 8.8 42 4.3 1.8 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain MBT PF02820.18 KFP10765.1 - 4.4e-93 305.7 6.2 1.2e-23 83.2 0.1 4.7 5 0 0 5 5 5 4 mbt repeat SLED PF12140.8 KFP10765.1 - 7.2e-39 132.8 0.1 1.6e-38 131.7 0.1 1.6 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFP10765.1 - 2.6e-08 34.2 0.0 5.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP10765.1 - 2.8e-05 24.0 0.0 9.4e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 KFP10765.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFP10765.1 - 0.0032 17.7 1.0 0.012 15.8 0.1 2.3 1 1 1 2 2 2 1 Ste50p, sterile alpha motif STIMATE PF12400.8 KFP10766.1 - 1.1e-33 116.4 10.3 1.6e-33 115.9 10.3 1.2 1 0 0 1 1 1 1 STIMATE family Vpu PF00558.19 KFP10766.1 - 0.05 13.4 0.7 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Vpu protein TMEM154 PF15102.6 KFP10766.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family ITI_HC_C PF06668.12 KFP10767.1 - 3.1e-71 238.9 0.1 6.8e-71 237.8 0.1 1.6 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.10 KFP10767.1 - 2.2e-29 101.9 1.2 4.5e-29 100.9 1.2 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFP10767.1 - 7e-21 75.2 0.2 1.3e-20 74.4 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP10767.1 - 5e-18 65.5 0.0 7.9e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP10767.1 - 2.5e-12 47.4 0.1 8.7e-12 45.6 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP10767.1 - 0.00021 20.8 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Kin17_mid PF10357.9 KFP10768.1 - 1.2e-50 170.7 3.2 1.2e-50 170.7 3.2 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KFP10768.1 - 9.9e-23 80.0 5.9 5.5e-22 77.6 6.4 1.9 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 KFP10768.1 - 0.00049 19.9 3.7 0.001 18.9 0.0 3.1 2 1 1 3 3 3 1 KOW motif SecM PF06558.12 KFP10768.1 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Secretion monitor precursor protein (SecM) Caskin-tail PF16632.5 KFP10768.1 - 0.099 13.1 0.3 0.45 11.0 0.3 2.1 1 0 0 1 1 1 0 C-terminal region of Caskin ATP-synt PF00231.19 KFP10769.1 - 1.6e-76 257.7 5.2 1.8e-76 257.6 5.2 1.0 1 0 0 1 1 1 1 ATP synthase PHD PF00628.29 KFP10770.1 - 1e-10 41.3 7.1 2.4e-10 40.1 7.1 1.7 1 0 0 1 1 1 1 PHD-finger RNA_pol_Rpc4 PF05132.14 KFP10770.1 - 0.0035 17.8 13.8 0.0035 17.8 13.8 5.8 5 1 0 5 5 5 1 RNA polymerase III RPC4 PHD_2 PF13831.6 KFP10770.1 - 0.0054 16.3 1.8 0.0054 16.3 1.8 2.1 2 0 0 2 2 2 1 PHD-finger DUF4471 PF14740.6 KFP10770.1 - 0.062 12.5 0.0 0.062 12.5 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4471) GATA PF00320.27 KFP10771.1 - 1.1e-29 101.7 19.4 8.1e-15 54.1 5.2 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFP10771.1 - 9.9e-06 25.0 7.9 0.017 14.6 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KFP10771.1 - 0.0045 17.1 5.1 1.8 8.8 0.6 3.3 1 1 2 3 3 3 1 Probable metal-binding protein (DUF2387) ArfGap PF01412.18 KFP10771.1 - 0.027 14.6 8.3 0.071 13.2 0.4 2.5 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 KFP10771.1 - 0.031 14.4 4.3 1.8 8.8 0.1 2.9 3 1 0 3 3 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KFP10771.1 - 0.048 13.8 5.2 0.89 9.8 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TDP43_N PF18694.1 KFP10771.1 - 0.18 11.7 0.2 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Prim_Zn_Ribbon PF08273.12 KFP10771.1 - 0.76 10.1 10.9 0.27 11.5 2.1 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.7 KFP10771.1 - 1.2 9.2 13.4 4.8 7.3 2.4 3.1 1 1 2 3 3 3 0 Double zinc ribbon Elf1 PF05129.13 KFP10771.1 - 2.6 8.1 7.8 8.1 6.6 0.3 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 KFP10771.1 - 3.5 7.6 13.1 5.5 7.0 2.7 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KFP10771.1 - 3.8 7.4 8.9 12 5.9 1.2 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.5 KFP10771.1 - 4.3 6.8 8.7 0.94 8.9 0.4 3.0 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Miga PF10265.9 KFP10773.1 - 2.3e-255 848.7 4.2 2.6e-255 848.5 4.2 1.0 1 0 0 1 1 1 1 Mitoguardin I-set PF07679.16 KFP10774.1 - 2.4e-18 66.0 0.0 7.7e-18 64.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP10774.1 - 2.2e-10 41.0 0.0 6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP10774.1 - 8.1e-07 29.1 0.1 3.5e-06 27.1 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP10774.1 - 0.0051 17.1 0.0 0.009 16.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain COMM_domain PF07258.14 KFP10774.1 - 0.58 10.3 4.8 2.2 8.4 4.8 2.0 1 0 0 1 1 1 0 COMM domain KH_1 PF00013.29 KFP10775.1 - 4e-65 215.6 16.9 2.1e-18 65.9 0.1 4.5 4 1 0 4 4 4 4 KH domain KH_2 PF07650.17 KFP10775.1 - 1.1e-18 66.8 10.3 3.3e-05 23.6 0.3 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KFP10775.1 - 6.4e-13 47.9 20.7 1.1e-06 28.0 6.9 3.8 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.6 KFP10775.1 - 5.7e-06 26.1 8.4 0.17 11.8 0.1 4.2 4 0 0 4 4 4 3 KH domain Secretin_N PF03958.17 KFP10775.1 - 0.00077 19.8 1.0 0.094 13.1 0.7 3.3 3 1 1 4 4 4 1 Bacterial type II/III secretion system short domain KH_5 PF13184.6 KFP10775.1 - 0.91 9.7 9.7 4.5 7.4 0.1 3.6 4 0 0 4 4 4 0 NusA-like KH domain DnaJ_C PF01556.18 KFP10776.1 - 7e-44 149.5 0.1 9.2e-44 149.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP10776.1 - 3.2e-28 97.6 2.9 5.8e-28 96.8 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain PDZ PF00595.24 KFP10777.1 - 1.9e-07 31.3 0.0 3.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP10777.1 - 0.0088 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Vitellogenin_N PF01347.22 KFP10778.1 - 1.1e-151 506.3 0.7 1.1e-151 506.3 0.7 3.9 2 1 0 2 2 2 1 Lipoprotein amino terminal region DUF1944 PF09175.10 KFP10778.1 - 8.5e-58 194.9 0.6 2.1e-57 193.6 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) DUF1943 PF09172.11 KFP10778.1 - 1.7e-57 195.0 0.2 1.7e-57 195.0 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1943) VWD PF00094.25 KFP10778.1 - 4.8e-24 85.4 1.8 4.8e-24 85.4 1.8 2.6 3 0 0 3 3 3 1 von Willebrand factor type D domain Utp14 PF04615.13 KFP10778.1 - 5.1 5.6 39.5 8.9 4.7 39.5 1.3 1 0 0 1 1 1 0 Utp14 protein 7tm_2 PF00002.24 KFP10779.1 - 2.6e-58 197.2 27.9 4.9e-58 196.3 27.9 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFP10779.1 - 1.1e-43 149.2 6.6 1.4e-43 148.8 6.6 1.1 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain EGF_CA PF07645.15 KFP10779.1 - 8.9e-16 57.8 46.8 1.2e-08 35.0 10.5 3.8 3 1 0 3 3 3 3 Calcium-binding EGF domain GPS PF01825.21 KFP10779.1 - 2.7e-15 56.6 6.6 2.7e-15 56.6 6.6 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif cEGF PF12662.7 KFP10779.1 - 8.2e-12 44.8 23.1 5.3e-08 32.7 0.9 3.8 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP10779.1 - 4.3e-11 42.8 56.1 1.4e-05 25.2 7.7 5.1 5 0 0 5 5 5 3 EGF domain Plasmod_Pvs28 PF06247.11 KFP10779.1 - 0.00026 21.3 46.9 0.0041 17.4 4.7 5.0 5 0 0 5 5 4 3 Pvs28 EGF domain hEGF PF12661.7 KFP10779.1 - 0.00096 19.7 5.6 0.00096 19.7 5.6 5.0 6 0 0 6 6 4 2 Human growth factor-like EGF FXa_inhibition PF14670.6 KFP10779.1 - 0.0011 19.2 6.2 0.0011 19.2 6.2 4.1 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP10779.1 - 0.0038 17.5 50.9 0.017 15.5 6.7 5.1 5 2 0 5 5 4 3 EGF-like domain DUF2371 PF10177.9 KFP10779.1 - 0.19 11.9 1.9 0.51 10.5 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Pox_A14 PF05767.12 KFP10779.1 - 1.7 8.9 9.4 0.74 10.0 3.4 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Latrophilin PF02354.16 KFP10781.1 - 7.5e-174 578.1 13.4 1e-173 577.7 13.4 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.16 KFP10781.1 - 5.9e-85 284.8 5.4 1.1e-84 283.9 5.4 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.24 KFP10781.1 - 1.9e-68 230.4 17.9 2.8e-68 229.9 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFP10781.1 - 2.3e-54 184.0 0.6 3.5e-54 183.4 0.6 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFP10781.1 - 1.1e-23 83.5 0.7 3e-23 82.1 0.7 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.21 KFP10781.1 - 2.9e-15 56.5 5.8 8.1e-15 55.1 5.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFP10781.1 - 8.8e-09 35.5 1.3 2.3e-08 34.2 1.3 1.8 1 0 0 1 1 1 1 Hormone receptor domain DUF5074 PF16819.5 KFP10781.1 - 0.75 9.9 5.3 1.5 8.9 0.8 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5074) zf-C2HCIx2C PF10782.9 KFP10781.1 - 0.92 9.5 4.8 2.1 8.3 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger Keratin_assoc PF09775.9 KFP10782.1 - 5.2e-56 187.8 6.2 5.9e-56 187.6 6.2 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 FNIP PF05725.12 KFP10782.1 - 0.097 12.8 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 FNIP Repeat DUF5408 PF17402.2 KFP10782.1 - 0.37 10.7 3.0 0.25 11.3 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5408) EptA_B_N PF08019.12 KFP10782.1 - 0.77 9.6 7.1 6 6.7 2.8 2.1 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB DUF3328 PF11807.8 KFP10783.1 - 0.005 16.6 0.1 0.0054 16.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TMEM52 PF14979.6 KFP10783.1 - 0.008 16.1 0.5 0.0086 16.0 0.5 1.1 1 0 0 1 1 1 1 Transmembrane 52 DUF5527 PF17665.1 KFP10783.1 - 0.0097 15.4 0.3 0.012 15.1 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5527) EphA2_TM PF14575.6 KFP10783.1 - 0.015 16.2 0.0 0.017 16.0 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KFP10783.1 - 0.021 15.3 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Ninjurin PF04923.12 KFP10783.1 - 0.068 13.1 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Ninjurin Glyco_hydro_30 PF02055.16 KFP10784.1 - 4.2e-169 562.0 0.4 4.9e-169 561.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KFP10784.1 - 3e-08 33.8 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFP10784.1 - 6.1e-08 32.2 0.1 9.8e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 CD20 PF04103.15 KFP10785.1 - 2.1e-18 66.9 16.3 6.4e-18 65.3 16.3 1.7 1 1 0 1 1 1 1 CD20-like family DUF5472 PF17566.2 KFP10785.1 - 0.041 13.8 0.8 0.075 13.0 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5472) DUF3040 PF11239.8 KFP10785.1 - 0.42 10.9 4.7 1.5 9.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Pkinase PF00069.25 KFP10786.1 - 2.3e-51 174.7 0.1 2.9e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10786.1 - 4.3e-21 75.4 0.1 1.5e-20 73.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ion_trans PF00520.31 KFP10787.1 - 1.1e-23 83.7 13.3 1.8e-23 83.0 13.3 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFP10787.1 - 2.1e-18 66.2 0.0 4.3e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP10787.1 - 6.1e-05 22.9 0.1 0.00021 21.2 0.1 1.9 2 0 0 2 2 2 1 Ion channel RUN PF02759.19 KFP10788.1 - 4.8e-18 65.4 0.0 1e-17 64.4 0.0 1.5 2 0 0 2 2 2 1 RUN domain SH3_1 PF00018.28 KFP10788.1 - 7e-09 35.2 0.0 1.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP10788.1 - 1.8e-07 30.9 0.0 5.8e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP10788.1 - 2e-07 30.6 0.0 9.6e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain DAP3 PF10236.9 KFP10789.1 - 6.5e-77 258.8 0.0 8.1e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 KFP10789.1 - 0.038 13.5 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFP10789.1 - 0.039 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFP10789.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFP10789.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KFP10789.1 - 0.06 13.4 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KFP10789.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PAH PF02671.21 KFP10790.1 - 2.5e-11 43.5 3.0 1.5e-06 28.3 0.1 3.4 3 0 0 3 3 3 2 Paired amphipathic helix repeat Myb_DNA-bind_6 PF13921.6 KFP10790.1 - 0.00035 20.8 0.1 0.015 15.6 0.1 3.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFP10790.1 - 0.0052 17.0 0.4 0.039 14.2 0.0 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Proteasom_Rpn13 PF04683.13 KFP10790.1 - 0.084 13.4 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor C2 PF00168.30 KFP10791.1 - 8.5e-46 154.5 0.1 2.1e-21 76.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFP10791.1 - 0.00031 20.4 0.0 0.1 12.2 0.0 2.6 2 1 0 2 2 2 2 CEP76 C2 domain PTEN_C2 PF10409.9 KFP10791.1 - 0.016 14.9 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein CoatB PF10389.9 KFP10791.1 - 0.36 10.7 4.0 0.75 9.7 4.0 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B RVT_1 PF00078.27 KFP10792.1 - 0.0027 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2756 PF10956.8 KFP10793.1 - 0.049 14.1 3.5 0.22 12.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) GCN5L1 PF06320.13 KFP10794.1 - 0.0074 16.4 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Calc_CGRP_IAPP PF00214.19 KFP10794.1 - 0.1 12.9 0.5 0.29 11.5 0.5 1.7 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family GPP34 PF05719.11 KFP10795.1 - 5.6e-50 170.2 0.8 6.4e-50 170.0 0.8 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Endosulfine PF04667.17 KFP10796.1 - 8.2e-11 41.9 1.4 1.1e-10 41.5 1.4 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox30 PF15532.6 KFP10796.1 - 0.06 13.7 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 30 Bcl-2 PF00452.19 KFP10797.1 - 2.5e-18 66.6 0.3 3.6e-18 66.1 0.3 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BALF1 PF06861.11 KFP10797.1 - 0.022 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 BALF1 protein 7tm_1 PF00001.21 KFP10798.1 - 1e-36 126.6 22.8 1.3e-36 126.3 22.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP10798.1 - 0.00093 19.0 19.0 0.021 14.6 19.0 2.6 1 1 0 1 1 1 1 Olfactory receptor Corona_NSP4_C PF16348.5 KFP10798.1 - 0.0082 16.9 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Coronavirus nonstructural protein 4 C-terminus DUF778 PF05608.12 KFP10799.1 - 8.9e-43 146.9 5.7 2.1e-21 77.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) WD40 PF00400.32 KFP10801.1 - 1.4e-23 82.7 5.6 2e-06 28.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat TPR_19 PF14559.6 KFP10801.1 - 2.4e-07 31.2 1.8 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KFP10801.1 - 5e-06 26.7 0.1 0.0064 16.8 0.2 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KFP10801.1 - 6.2e-06 25.9 8.4 0.051 13.7 0.4 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP10801.1 - 1.5e-05 25.0 2.2 0.032 14.6 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP10801.1 - 1.5e-05 24.6 10.4 0.14 12.0 1.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP10801.1 - 2.7e-05 24.3 4.7 5.3e-05 23.4 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFP10801.1 - 3.2e-05 24.4 0.8 0.35 11.8 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP10801.1 - 3.9e-05 23.2 1.4 0.00023 20.8 0.9 2.2 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 KFP10801.1 - 0.00041 20.8 0.3 0.31 11.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP10801.1 - 0.058 14.1 2.8 8.9 7.1 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP10801.1 - 0.23 11.6 0.6 1.6 8.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP10801.1 - 0.3 11.4 1.1 9.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 KFP10802.1 - 5.4e-85 285.5 43.8 6.9e-85 285.1 43.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family OprF PF05736.11 KFP10802.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 OprF membrane domain NTP_transf_7 PF07984.12 KFP10803.1 - 1.1e-143 478.3 0.9 1.2e-143 478.1 0.9 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase DUF4656 PF15551.6 KFP10804.1 - 4.3e-194 645.0 14.9 4.9e-194 644.8 14.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4656) CS PF04969.16 KFP10805.1 - 8.4e-20 71.6 0.4 3.5e-19 69.6 0.1 2.2 2 0 0 2 2 2 1 CS domain NuDC PF16273.5 KFP10805.1 - 2.6e-18 66.3 21.2 2.6e-18 66.3 21.2 3.2 2 2 1 3 3 3 1 Nuclear distribution C domain Nudc_N PF14050.6 KFP10805.1 - 2.8e-05 24.0 3.0 2.8e-05 24.0 3.0 2.0 2 1 0 2 2 2 1 N-terminal conserved domain of Nudc. Hormone_recep PF00104.30 KFP10806.1 - 2.8e-24 85.8 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor G-patch PF01585.23 KFP10807.1 - 7.4e-09 35.4 1.1 1.4e-08 34.5 1.1 1.5 1 0 0 1 1 1 1 G-patch domain 14-3-3 PF00244.20 KFP10808.1 - 1.1e-102 342.2 6.9 1.3e-102 342.0 6.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Anticodon_1 PF08264.13 KFP10808.1 - 0.028 14.4 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Peptidase_C98 PF15499.6 KFP10808.1 - 0.034 13.6 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FliM PF02154.15 KFP10808.1 - 0.1 12.4 0.2 0.33 10.8 0.0 1.8 2 1 1 3 3 3 0 Flagellar motor switch protein FliM DHHC PF01529.20 KFP10809.1 - 4.5e-36 123.9 10.9 4.5e-36 123.9 10.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.6 KFP10809.1 - 2.3 7.8 4.3 4.6 6.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Mannosyl_trans2 PF04188.13 KFP10810.1 - 6.3e-126 421.3 3.0 5.5e-100 335.8 0.9 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) BAF250_C PF12031.8 KFP10811.1 - 6.6e-120 399.2 0.0 1.2e-119 398.3 0.0 1.5 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFP10811.1 - 3.2e-14 53.3 0.0 7.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 KFP10812.1 - 3e-144 479.2 0.0 8.7e-76 254.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10812.1 - 4.8e-73 245.6 0.0 6.6e-37 127.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP10812.1 - 1.4e-11 44.2 0.0 0.00021 20.7 0.0 3.3 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KFP10812.1 - 3.5e-11 42.9 0.0 2e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP10812.1 - 3.6e-09 35.9 0.0 0.00047 19.1 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 KFP10812.1 - 1.2e-06 27.7 0.2 0.027 13.4 0.1 2.3 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KFP10812.1 - 5.3e-05 23.3 0.0 0.29 11.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFP10812.1 - 0.00017 21.3 0.1 3.3 7.3 0.0 3.4 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KFP10812.1 - 0.001 18.7 0.0 0.27 10.7 0.0 2.8 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL tRNA-synt_1f PF01921.18 KFP10812.1 - 0.0034 16.4 0.0 0.0067 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) Pkinase_C PF00433.24 KFP10812.1 - 0.014 16.0 0.0 0.054 14.2 0.0 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.22 KFP10812.1 - 0.028 14.0 0.0 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KFP10812.1 - 0.043 13.1 0.0 24 4.1 0.0 3.1 3 0 0 3 3 3 0 Ecdysteroid kinase HMG14_17 PF01101.18 KFP10813.1 - 1e-25 90.5 20.3 1.2e-25 90.3 20.3 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 Prenyltransf PF01255.19 KFP10814.1 - 4.6e-77 258.5 0.0 6.1e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AATase PF07247.12 KFP10814.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase CSD PF00313.22 KFP10815.1 - 2e-06 27.6 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Rsm22 PF09243.10 KFP10815.1 - 0.063 12.5 0.5 0.071 12.4 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CusF_Ec PF11604.8 KFP10815.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF zf-CCHC PF00098.23 KFP10815.1 - 0.32 11.2 3.0 0.24 11.5 1.0 1.8 2 0 0 2 2 2 0 Zinc knuckle SEP PF08059.13 KFP10816.1 - 1.7e-21 76.5 0.3 6e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFP10816.1 - 5.2e-10 39.4 0.0 2.1e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 UBX domain TMPIT PF07851.13 KFP10816.1 - 0.0041 16.4 1.5 0.006 15.9 1.5 1.1 1 0 0 1 1 1 1 TMPIT-like protein DivIC PF04977.15 KFP10816.1 - 0.024 14.4 2.3 0.072 12.9 2.3 1.8 1 0 0 1 1 1 0 Septum formation initiator Csm1_N PF18504.1 KFP10816.1 - 0.037 14.4 2.5 0.1 13.0 2.5 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain CC2-LZ PF16516.5 KFP10816.1 - 0.098 13.0 3.9 0.22 11.9 3.9 1.6 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BRE1 PF08647.11 KFP10816.1 - 0.13 12.4 4.6 0.35 11.0 4.6 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 KFP10816.1 - 0.14 11.2 0.7 0.2 10.7 0.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 KFP10816.1 - 0.15 12.6 4.8 0.42 11.1 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_lid_8 PF17868.1 KFP10816.1 - 0.19 11.7 0.4 0.48 10.4 0.4 1.7 1 0 0 1 1 1 0 AAA lid domain XLF PF09302.11 KFP10816.1 - 0.23 11.6 3.8 1.1 9.4 2.6 2.3 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FAM76 PF16046.5 KFP10816.1 - 0.35 10.2 4.7 0.54 9.6 4.7 1.2 1 0 0 1 1 1 0 FAM76 protein XhlA PF10779.9 KFP10816.1 - 0.74 10.1 3.4 2.3 8.5 3.4 1.8 1 0 0 1 1 1 0 Haemolysin XhlA KASH_CCD PF14662.6 KFP10816.1 - 1.1 9.1 11.1 1 9.1 7.6 2.4 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH SH3BGR PF04908.15 KFP10817.1 - 5.3e-31 106.7 0.1 5.9e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFP10817.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KFP10817.1 - 0.079 13.4 0.0 0.093 13.2 0.0 1.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PI_PP_I PF18363.1 KFP10818.1 - 1.3 9.3 6.1 3.2 8.0 0.1 3.3 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain ATP-synt_Eps PF04627.13 KFP10818.1 - 3.3 7.8 4.3 2.4 8.2 0.8 2.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Pkinase PF00069.25 KFP10820.1 - 3.8e-52 177.2 0.0 1.5e-51 175.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10820.1 - 3.2e-32 111.9 0.5 4.4e-28 98.3 0.5 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP10820.1 - 0.0021 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP10820.1 - 0.0083 16.1 0.2 0.064 13.2 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP10820.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP10820.1 - 0.032 13.5 0.0 0.075 12.3 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KFP10820.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFP10820.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING_UBOX PF13445.6 KFP10821.1 - 1.4e-10 41.0 3.6 4.4e-10 39.4 3.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP10821.1 - 1.8e-08 34.1 2.7 1.8e-08 34.1 2.7 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP10821.1 - 7.1e-08 32.2 3.4 7.1e-08 32.2 3.4 2.9 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP10821.1 - 2.8e-07 30.4 4.9 2.8e-07 30.4 4.9 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP10821.1 - 9.7e-07 29.0 5.4 9.7e-07 29.0 5.4 3.0 2 1 0 2 2 1 1 Ring finger domain zf-B_box PF00643.24 KFP10821.1 - 1.4e-06 28.4 6.5 1.4e-06 28.4 6.5 3.7 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_3 PF13920.6 KFP10821.1 - 3.1e-06 26.9 7.1 3.1e-06 26.9 7.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP10821.1 - 5.9e-06 26.3 6.6 5.9e-06 26.3 6.6 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFP10821.1 - 0.00011 21.9 0.2 0.00011 21.9 0.2 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF745 PF05335.13 KFP10821.1 - 0.0012 18.6 2.7 0.1 12.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) SHE3 PF17078.5 KFP10821.1 - 0.0098 15.6 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Zn-C2H2_12 PF18112.1 KFP10821.1 - 0.84 10.2 5.1 0.7 10.4 1.3 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_11 PF17123.5 KFP10821.1 - 1.8 8.4 10.5 0.99 9.2 6.2 2.7 2 0 0 2 2 2 0 RING-like zinc finger Cation_efflux PF01545.21 KFP10822.1 - 8.8e-27 94.1 7.9 1e-26 93.9 5.9 1.8 2 0 0 2 2 2 1 Cation efflux family Ocular_alb PF02101.15 KFP10822.1 - 0.011 14.7 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 0 Ocular albinism type 1 protein Oxidored_q5_N PF01059.17 KFP10822.1 - 0.79 9.8 3.9 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Stathmin PF00836.19 KFP10823.1 - 1.8e-47 160.7 22.7 2.9e-47 160.0 22.7 1.3 1 1 0 1 1 1 1 Stathmin family Ribonuc_2-5A PF06479.12 KFP10823.1 - 0.22 11.7 3.2 0.35 11.1 3.2 1.5 1 1 0 1 1 1 0 Ribonuclease 2-5A COX16 PF14138.6 KFP10823.1 - 5 7.7 7.9 9.8 6.8 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Mito_fiss_reg PF05308.11 KFP10824.1 - 7e-73 245.8 1.6 8.4e-73 245.5 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator EF-hand_7 PF13499.6 KFP10826.1 - 0.0018 18.7 0.0 0.0056 17.1 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair DUF1322 PF07032.11 KFP10826.1 - 0.058 13.9 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) SPARC_Ca_bdg PF10591.9 KFP10826.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Macoilin PF09726.9 KFP10828.1 - 0 1060.9 18.5 0 1060.7 18.5 1.0 1 0 0 1 1 1 1 Macoilin family DUF812 PF05667.11 KFP10828.1 - 0.0011 18.0 40.5 0.0011 18.0 40.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF812) HU-CCDC81_bac_2 PF18175.1 KFP10828.1 - 0.098 12.5 3.6 1.2 9.0 0.1 3.6 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 FPP PF05911.11 KFP10828.1 - 1.1 7.4 49.9 0.33 9.1 27.8 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Mto2_bdg PF12808.7 KFP10828.1 - 3.5 8.0 19.1 2.9 8.3 1.6 4.1 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GLE1 PF07817.13 KFP10828.1 - 4.5 6.4 18.2 0.36 10.0 0.3 2.6 3 0 0 3 3 3 0 GLE1-like protein DUF1974 PF09317.11 KFP10828.1 - 7.7 6.0 16.8 0.81 9.2 10.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1974) Ammonium_transp PF00909.21 KFP10829.1 - 1.6e-48 165.4 20.2 2.2e-48 164.9 20.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3742 PF12553.8 KFP10829.1 - 0.37 10.9 2.6 33 4.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) UPF0220 PF05255.11 KFP10830.1 - 4e-47 159.9 5.2 4.4e-47 159.7 5.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RSRP PF17069.5 KFP10831.1 - 3.1e-54 184.6 84.7 4.2e-54 184.2 84.7 1.2 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 Pol_alpha_B_N PF08418.10 KFP10831.1 - 6 6.8 10.8 1.5 8.8 6.3 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal SYF2 PF08231.12 KFP10832.1 - 7.2e-57 192.2 11.1 7.2e-57 192.2 11.1 1.6 2 0 0 2 2 2 1 SYF2 splicing factor FUSC-like PF12805.7 KFP10832.1 - 0.0058 15.7 0.2 0.0082 15.3 0.2 1.2 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS rve_3 PF13683.6 KFP10832.1 - 0.022 14.6 0.2 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain ARD PF03079.14 KFP10832.1 - 7.2 6.8 9.4 0.58 10.3 0.7 2.4 1 1 2 3 3 3 0 ARD/ARD' family Runt PF00853.19 KFP10833.1 - 2.3e-53 179.2 0.7 3.5e-53 178.6 0.7 1.3 1 0 0 1 1 1 1 Runt domain RunxI PF08504.11 KFP10833.1 - 3.9e-45 152.6 5.9 1.1e-44 151.2 5.9 1.8 1 0 0 1 1 1 1 Runx inhibition domain GST_C_2 PF13410.6 KFP10835.1 - 3.1e-07 30.3 0.0 6.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP10835.1 - 3.7e-05 24.1 0.0 6.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFP10835.1 - 4e-05 23.8 0.0 8.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP10835.1 - 0.0047 17.1 0.2 0.03 14.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SKG6 PF08693.10 KFP10836.1 - 0.00058 19.2 1.0 0.001 18.5 1.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2207 PF09972.9 KFP10836.1 - 0.0023 16.8 0.0 0.0026 16.6 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RIFIN PF02009.16 KFP10836.1 - 0.0043 17.0 0.3 0.0055 16.7 0.3 1.1 1 0 0 1 1 1 1 Rifin Glycophorin_A PF01102.18 KFP10836.1 - 0.005 17.1 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 Glycophorin A Amnionless PF14828.6 KFP10836.1 - 0.0089 14.9 0.1 0.0096 14.8 0.1 1.0 1 0 0 1 1 1 1 Amnionless DUF2976 PF11190.8 KFP10836.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) TMEM154 PF15102.6 KFP10836.1 - 0.011 15.7 0.2 0.013 15.4 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 KFP10836.1 - 0.018 14.4 0.3 0.023 14.1 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MscL PF01741.18 KFP10836.1 - 0.019 15.3 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Presenilin PF01080.17 KFP10836.1 - 0.027 13.2 0.3 0.034 12.9 0.3 1.1 1 0 0 1 1 1 0 Presenilin EphA2_TM PF14575.6 KFP10836.1 - 0.034 15.0 0.0 0.055 14.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain m04gp34like PF12216.8 KFP10836.1 - 0.038 13.5 0.1 0.049 13.2 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein Adeno_E3_CR2 PF02439.15 KFP10836.1 - 0.044 13.5 2.5 0.064 13.0 2.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM51 PF15345.6 KFP10836.1 - 0.047 13.5 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 UL45 PF05473.12 KFP10836.1 - 0.049 13.3 0.7 0.068 12.8 0.3 1.5 1 1 1 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Shisa PF13908.6 KFP10836.1 - 0.057 13.7 0.2 0.069 13.4 0.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RCR PF12273.8 KFP10836.1 - 0.078 13.6 0.8 0.079 13.6 0.1 1.4 2 0 0 2 2 1 0 Chitin synthesis regulation, resistance to Congo red Syndecan PF01034.20 KFP10836.1 - 0.08 12.9 1.3 0.12 12.3 1.3 1.3 1 0 0 1 1 1 0 Syndecan domain Calcipressin PF04847.12 KFP10837.1 - 2.4e-61 206.7 0.7 3.3e-61 206.3 0.7 1.2 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 KFP10837.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP10837.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mg_trans_NIPA PF05653.14 KFP10838.1 - 1.1e-71 241.4 21.0 1.3e-71 241.1 21.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA 7TMR-DISM_7TM PF07695.11 KFP10838.1 - 0.27 11.1 34.2 0.2 11.5 18.8 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2663 PF10864.8 KFP10838.1 - 7.8 6.9 6.3 0.96 9.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) CP2 PF04516.15 KFP10839.1 - 2.9e-86 288.5 0.1 3.9e-86 288.1 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tissue_fac PF01108.17 KFP10840.1 - 3.6e-24 84.7 0.1 6.4e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP10840.1 - 1.4e-08 35.0 0.1 3.9e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP10840.1 - 7.9e-05 22.9 1.0 0.00069 19.9 0.2 2.5 2 1 0 2 2 2 1 Fibronectin type III domain IL6Ra-bind PF09240.10 KFP10840.1 - 0.0047 17.3 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Calici_coat_C PF08435.11 KFP10840.1 - 0.095 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Tissue_fac PF01108.17 KFP10841.1 - 3e-24 84.9 0.3 3.2e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Tissue factor fn3 PF00041.21 KFP10842.1 - 1.9e-86 284.5 0.2 8.6e-18 64.5 0.0 6.0 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFP10842.1 - 1.1e-63 211.2 5.1 9.9e-18 64.0 0.2 7.9 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP10842.1 - 4.4e-46 155.4 0.7 4.7e-10 39.9 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFP10842.1 - 2.1e-27 95.1 6.7 0.00018 21.6 0.1 7.6 7 0 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 KFP10842.1 - 8.6e-27 93.3 2.2 4.5e-06 26.9 0.0 6.5 6 0 0 6 6 6 4 Immunoglobulin domain V-set PF07686.17 KFP10842.1 - 2.5e-15 56.6 19.9 0.098 12.8 0.1 10.6 7 4 1 8 8 8 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP10842.1 - 4.4e-10 40.0 1.1 0.082 13.5 0.0 6.8 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFP10842.1 - 3.4e-07 30.1 0.1 1.5 8.7 0.0 5.5 5 0 0 5 5 5 3 Tissue factor C2-set_2 PF08205.12 KFP10842.1 - 2.1e-06 27.7 0.2 0.22 11.6 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 KFP10842.1 - 0.00027 21.0 0.0 0.049 13.8 0.0 3.1 2 0 0 2 2 2 1 Fibronectin type III domain Receptor_2B4 PF11465.8 KFP10842.1 - 0.0013 18.9 5.4 12 6.1 0.0 6.0 6 0 0 6 6 6 1 Natural killer cell receptor 2B4 DUF4926 PF16277.5 KFP10842.1 - 0.0066 15.8 0.3 1.1 8.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4926) NOD2_WH PF17779.1 KFP10842.1 - 0.16 12.3 0.0 90 3.5 0.0 3.6 3 0 0 3 3 3 0 NOD2 winged helix domain Lipocalin_7 PF14651.6 KFP10843.1 - 3.1e-32 111.2 1.8 3.4e-32 111.1 1.8 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFP10843.1 - 1.7e-17 63.9 2.2 1.9e-17 63.8 2.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family RRM_1 PF00076.22 KFP10844.1 - 1.3e-10 40.9 0.0 3e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PipA PF07108.11 KFP10844.1 - 0.0027 17.3 0.1 0.004 16.7 0.1 1.2 1 0 0 1 1 1 1 PipA protein PNRC PF15365.6 KFP10845.1 - 3.6e-07 29.8 6.7 3.6e-07 29.8 6.7 1.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Ribosomal_S20p PF01649.18 KFP10845.1 - 0.022 15.4 2.2 0.031 14.9 2.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 7tm_1 PF00001.21 KFP10846.1 - 1.4e-39 136.0 22.5 1.8e-39 135.7 22.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP10846.1 - 1.6e-11 44.4 16.2 4.6e-11 43.0 16.2 1.7 1 1 0 1 1 1 1 Olfactory receptor Abhydrolase_9_N PF15420.6 KFP10846.1 - 2.7 7.9 7.5 6.6 6.7 7.3 1.8 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus WBP-1 PF11669.8 KFP10846.1 - 4 8.1 6.8 1.2 9.8 3.0 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 Alpha_L_fucos PF01120.17 KFP10847.1 - 4.4e-90 302.6 0.3 5.1e-90 302.4 0.3 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFP10847.1 - 1.2e-20 73.9 0.1 3.6e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain HMGL-like PF00682.19 KFP10848.1 - 2.4e-64 217.5 0.1 2.6e-64 217.3 0.1 1.0 1 0 0 1 1 1 1 HMGL-like AnfO_nitrog PF09582.10 KFP10848.1 - 0.092 12.1 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) GDP_Man_Dehyd PF16363.5 KFP10849.1 - 3.9e-56 190.8 0.0 4.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFP10849.1 - 1.9e-49 168.3 0.0 2.3e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFP10849.1 - 6.2e-18 64.8 0.0 1.6e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFP10849.1 - 2.8e-14 52.9 0.0 1.6e-11 43.9 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFP10849.1 - 4.4e-11 42.4 0.0 8.3e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFP10849.1 - 5.2e-06 25.8 0.0 0.00029 20.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KFP10849.1 - 1.5e-05 24.5 0.0 7.9e-05 22.2 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFP10849.1 - 1.9e-05 24.6 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFP10849.1 - 0.0002 21.3 0.0 0.00062 19.7 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFP10849.1 - 0.00071 19.2 0.1 0.34 10.4 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family Methyltransf_31 PF13847.6 KFP10849.1 - 0.087 12.6 0.0 7.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain L27 PF02828.16 KFP10849.1 - 0.2 11.5 0.2 0.36 10.6 0.2 1.4 1 0 0 1 1 1 0 L27 domain Abhydrolase_2 PF02230.16 KFP10850.1 - 3.7e-88 295.0 0.0 4.1e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP10850.1 - 3.3e-07 30.4 0.0 5.1e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP10850.1 - 1.3e-06 27.9 0.0 0.024 13.9 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP10850.1 - 6e-06 27.0 0.0 7.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFP10850.1 - 3.8e-05 23.3 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFP10850.1 - 0.00018 21.3 0.3 0.016 14.8 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KFP10850.1 - 0.00038 20.2 0.0 0.0045 16.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KFP10850.1 - 0.00064 19.3 0.1 0.091 12.2 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.22 KFP10850.1 - 0.0026 17.7 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Cutinase DUF2974 PF11187.8 KFP10850.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Palm_thioest PF02089.15 KFP10850.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AXE1 PF05448.12 KFP10850.1 - 0.21 10.2 0.0 0.36 9.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PITH PF06201.13 KFP10851.1 - 2.4e-30 105.8 0.0 3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain BLOC1S3 PF15753.5 KFP10851.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Elongin_A PF06881.11 KFP10852.1 - 9.2e-25 87.2 0.0 9.2e-25 87.2 0.0 2.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 KFP10852.1 - 3.1e-13 49.5 0.6 7.6e-13 48.3 0.6 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Kelch_6 PF13964.6 KFP10853.1 - 6.5e-34 115.1 0.4 1e-06 28.8 0.0 5.8 3 1 2 5 5 5 5 Kelch motif Kelch_1 PF01344.25 KFP10853.1 - 9.1e-34 114.8 11.1 4.6e-11 42.1 0.0 7.7 6 2 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP10853.1 - 8.5e-25 86.8 0.0 1.8e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFP10853.1 - 3.5e-21 75.5 0.8 6.2e-21 74.7 0.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFP10853.1 - 3.3e-20 71.9 11.5 3.9e-06 27.0 0.1 5.2 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP10853.1 - 6.2e-14 51.3 1.2 0.0011 18.9 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFP10853.1 - 4.4e-10 39.4 1.7 0.0076 16.2 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP10853.1 - 8.3e-08 32.1 0.2 0.33 11.0 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Ribosomal_L5 PF00281.19 KFP10854.1 - 7.4e-23 80.7 0.0 5.2e-21 74.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KFP10854.1 - 2.9e-21 75.4 0.0 4.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Palm_thioest PF02089.15 KFP10855.1 - 1.6e-75 254.1 0.0 1.8e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase CAP_N PF01213.19 KFP10856.1 - 3.6e-82 276.4 10.9 8.5e-78 262.0 1.1 2.8 2 2 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFP10856.1 - 5e-65 217.9 3.9 7e-65 217.4 3.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KFP10856.1 - 0.00011 21.9 2.1 0.0003 20.5 2.1 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C IPPT PF01715.17 KFP10857.1 - 1.9e-64 217.6 0.1 2.7e-64 217.1 0.1 1.2 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.8 KFP10857.1 - 5.7e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP10857.1 - 0.02 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF1394 PF07159.12 KFP10859.1 - 3.9e-101 338.3 3.1 4.4e-101 338.1 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) EF-hand_7 PF13499.6 KFP10860.1 - 9.9e-24 83.6 2.4 4.2e-14 52.7 0.3 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP10860.1 - 2.3e-23 80.0 14.9 9.3e-08 31.1 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP10860.1 - 2e-22 77.2 4.9 2.2e-07 30.3 0.1 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFP10860.1 - 1.3e-15 56.1 13.9 5.5e-06 25.6 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP10860.1 - 2.4e-12 46.5 10.6 4e-05 23.4 0.3 4.0 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP10860.1 - 0.0002 21.7 2.5 3.2 8.1 0.0 3.3 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP10860.1 - 0.0004 20.5 0.0 0.064 13.5 0.0 2.5 2 0 0 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 KFP10860.1 - 0.00064 19.7 3.0 0.068 13.1 3.0 3.2 1 1 0 1 1 1 1 Caleosin related protein p25-alpha PF05517.12 KFP10860.1 - 0.011 15.8 1.1 0.4 10.9 0.3 2.2 2 0 0 2 2 2 0 p25-alpha EF-hand_4 PF12763.7 KFP10860.1 - 0.021 14.8 6.1 2.7 8.0 0.3 3.5 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand YxiJ PF14176.6 KFP10860.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 YxiJ-like protein NETI PF14044.6 KFP10860.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NETI protein Beta-lactamase PF00144.24 KFP10860.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase 5-nucleotidase PF06189.12 KFP10861.1 - 2.4e-106 354.5 0.0 2.3e-105 351.3 0.0 1.9 1 1 1 2 2 2 2 5'-nucleotidase Hairy_orange PF07527.13 KFP10862.1 - 5.2e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFP10862.1 - 6e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pro_isomerase PF00160.21 KFP10863.1 - 7.3e-17 62.1 0.0 1e-16 61.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spectrin PF00435.21 KFP10865.1 - 8.6e-223 723.7 403.8 1.6e-17 63.9 5.0 41.7 40 2 2 42 42 42 34 Spectrin repeat CH PF00307.31 KFP10865.1 - 6.2e-45 151.9 9.8 1.5e-21 76.6 0.5 6.1 5 0 0 5 5 5 2 Calponin homology (CH) domain GAS2 PF02187.17 KFP10865.1 - 8.8e-33 112.2 0.5 3.1e-32 110.5 0.5 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin_like PF18373.1 KFP10865.1 - 7.8e-26 90.0 4.2 7.8e-26 90.0 4.2 7.9 8 0 0 8 8 8 1 Spectrin like domain SH3_10 PF17902.1 KFP10865.1 - 2.9e-20 72.1 0.3 8.6e-20 70.6 0.3 1.9 1 0 0 1 1 1 1 SH3 domain EF-hand_1 PF00036.32 KFP10865.1 - 1.2e-11 43.3 3.4 9.6e-05 21.7 0.7 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFP10865.1 - 3.1e-10 40.4 6.0 1.2e-09 38.5 0.9 4.3 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP10865.1 - 8e-10 37.9 6.1 0.00042 20.0 0.4 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFP10865.1 - 2.7e-08 33.5 0.6 2.5e-07 30.4 0.1 3.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP10865.1 - 2.7e-07 29.8 6.2 4.8e-05 22.6 1.1 3.4 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 KFP10865.1 - 1.1e-05 25.1 0.1 0.0078 16.0 0.0 3.2 2 0 0 2 2 2 1 CAMSAP CH domain Laminin_II PF06009.12 KFP10865.1 - 0.0003 20.8 4.3 0.0003 20.8 4.3 23.4 21 6 6 27 27 27 2 Laminin Domain II DUF1959 PF09218.10 KFP10865.1 - 1.2 9.3 5.1 1.7 8.8 0.1 3.8 3 0 0 3 3 2 0 Domain of unknown function (DUF1959) Zmiz1_N PF18028.1 KFP10865.1 - 1.3 9.4 11.6 1.8 8.9 0.1 6.2 5 0 0 5 5 5 0 Zmiz1 N-terminal tetratricopeptide repeat domain DUF2877 PF11392.8 KFP10865.1 - 2.5 8.8 4.9 33 5.2 0.2 4.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Orn_Arg_deC_N PF02784.16 KFP10867.1 - 1.2e-68 231.2 0.0 1.4e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFP10867.1 - 6.2e-07 29.6 0.0 2e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ADK PF00406.22 KFP10868.1 - 4.1e-52 176.3 0.0 4.8e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFP10868.1 - 3.2e-16 59.0 0.0 7.9e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFP10868.1 - 1.9e-15 57.5 0.0 4.1e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain IBR PF01485.21 KFP10869.1 - 5e-09 36.3 27.9 5.9e-08 32.8 9.6 3.4 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain EF-hand_7 PF13499.6 KFP10870.1 - 2.7e-27 95.0 3.0 6.5e-18 65.0 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP10870.1 - 1.1e-26 90.3 6.2 3e-07 29.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP10870.1 - 1e-23 81.2 1.2 5.5e-07 29.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP10870.1 - 3.5e-23 80.0 4.8 3.5e-07 29.4 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP10870.1 - 2.1e-19 69.1 4.3 6e-07 29.2 0.2 3.5 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP10870.1 - 2.3e-07 31.1 0.2 0.0031 17.8 0.1 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP10870.1 - 7.6e-07 29.0 0.8 0.28 11.2 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KFP10870.1 - 0.00074 19.3 0.1 1.7 8.5 0.0 3.1 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFP10870.1 - 0.0049 17.0 0.3 5.9 7.2 0.2 2.9 2 1 0 2 2 2 2 Dockerin type I domain DUF832 PF05734.11 KFP10870.1 - 0.083 12.4 0.2 2.2 7.7 0.2 2.0 1 1 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) tRNA-synt_1b PF00579.25 KFP10871.1 - 4.7e-76 255.9 0.0 6.1e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 KFP10871.1 - 1.3e-32 111.8 0.1 3.1e-32 110.5 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain Filament PF00038.21 KFP10874.1 - 2.3e-19 70.1 32.5 3.7e-19 69.4 32.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 KFP10874.1 - 1.2e-05 24.4 31.4 0.00031 19.7 13.7 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein CENP-H PF05837.12 KFP10874.1 - 0.0005 20.4 8.4 0.0005 20.4 8.4 3.4 2 2 1 3 3 3 1 Centromere protein H (CENP-H) Laminin_II PF06009.12 KFP10874.1 - 0.0024 17.9 19.1 0.084 12.9 4.8 3.2 2 1 1 3 3 3 2 Laminin Domain II Jnk-SapK_ap_N PF09744.9 KFP10874.1 - 0.0055 16.9 17.9 0.0055 16.9 17.9 2.7 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KFP10874.1 - 0.015 15.3 36.6 0.34 11.0 10.8 4.7 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Zein-binding PF04576.15 KFP10874.1 - 0.015 15.5 3.8 0.015 15.5 3.8 3.5 3 1 0 3 3 2 0 Zein-binding Cob_adeno_trans PF01923.18 KFP10874.1 - 0.016 15.4 10.7 0.018 15.2 1.1 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF1664 PF07889.12 KFP10874.1 - 0.033 14.2 16.9 1.5 8.8 4.0 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Peptidase_M26_C PF07580.14 KFP10874.1 - 0.065 11.7 0.3 0.15 10.5 0.2 1.6 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region NPV_P10 PF05531.12 KFP10874.1 - 0.098 13.1 5.7 31 5.1 0.6 4.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 KFP10874.1 - 0.1 12.7 27.5 0.65 10.1 0.3 5.8 5 1 1 6 6 6 0 bZIP transcription factor BRE1 PF08647.11 KFP10874.1 - 0.11 12.5 25.9 0.045 13.8 7.7 3.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 KFP10874.1 - 0.12 13.0 29.5 0.22 12.2 3.7 4.9 2 2 2 4 4 4 0 Initiation control protein YabA DUF4972 PF16342.5 KFP10874.1 - 0.16 11.7 3.7 0.32 10.7 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) CENP-F_leu_zip PF10473.9 KFP10874.1 - 0.18 11.8 45.6 0.17 11.9 10.5 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 KFP10874.1 - 0.22 11.0 32.8 0.058 12.9 10.2 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 KFP10874.1 - 0.46 10.5 8.8 11 6.1 0.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DinB_2 PF12867.7 KFP10874.1 - 0.48 10.9 4.5 2.3 8.7 0.7 2.8 2 2 0 2 2 2 0 DinB superfamily Cauli_AT PF03233.13 KFP10874.1 - 0.48 10.3 9.1 0.7 9.8 1.0 2.7 3 0 0 3 3 2 0 Aphid transmission protein Occludin_ELL PF07303.13 KFP10874.1 - 0.66 10.7 19.2 0.44 11.3 2.1 3.5 2 2 0 3 3 3 0 Occludin homology domain GAS PF13851.6 KFP10874.1 - 0.91 8.8 36.2 0.39 10.0 14.1 3.0 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KFP10874.1 - 1.6 9.2 33.7 1.7 9.0 13.0 2.3 1 1 0 2 2 2 0 Fez1 Bacillus_HBL PF05791.11 KFP10874.1 - 1.9 8.3 11.4 4.5 7.1 1.0 3.4 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) THOC7 PF05615.13 KFP10874.1 - 1.9 8.8 34.5 1.3 9.3 7.6 3.3 2 1 1 3 3 3 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 KFP10874.1 - 2 8.7 38.5 1.3 9.3 9.4 3.6 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TEX13 PF15186.6 KFP10874.1 - 2 8.1 27.4 0.38 10.4 2.9 3.9 3 1 1 4 4 4 0 Testis-expressed sequence 13 protein family Golgin_A5 PF09787.9 KFP10874.1 - 2.1 7.8 38.9 0.58 9.6 8.2 2.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 KFP10874.1 - 2.3 8.5 27.8 1.5 9.1 8.4 3.7 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 KFP10874.1 - 2.3 7.4 20.0 0.12 11.6 3.7 2.8 2 2 1 3 3 3 0 TMPIT-like protein UPF0242 PF06785.11 KFP10874.1 - 2.3 8.3 39.5 1.6 8.8 15.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MAD PF05557.13 KFP10874.1 - 2.7 6.2 37.7 21 3.3 14.4 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF3450 PF11932.8 KFP10874.1 - 3.1 7.1 29.6 1.5 8.1 1.4 3.8 2 2 3 5 5 5 0 Protein of unknown function (DUF3450) COG2 PF06148.11 KFP10874.1 - 4.2 7.5 21.4 14 5.8 2.5 4.0 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ATG16 PF08614.11 KFP10874.1 - 6.4 6.9 40.5 1.6 8.9 2.7 3.9 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 KFP10874.1 - 6.7 6.4 33.2 4 7.1 4.9 5.0 2 2 1 4 4 4 0 Domain of unknown function (DUF4201) Prp19 PF08606.11 KFP10874.1 - 9.4 6.3 17.2 0.049 13.6 3.1 3.8 3 1 0 3 3 3 0 Prp19/Pso4-like Prominin PF05478.11 KFP10874.1 - 9.5 4.0 19.4 0.51 8.2 7.5 2.2 1 1 1 2 2 2 0 Prominin CAF1C_H4-bd PF12265.8 KFP10875.1 - 2.5e-28 98.1 0.8 3.6e-27 94.4 0.2 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFP10875.1 - 1.1e-26 92.6 14.7 3.2e-07 30.9 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10875.1 - 6.4e-05 23.2 1.2 0.013 15.8 0.0 3.6 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP10875.1 - 0.00014 21.8 0.6 0.024 14.5 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.12 KFP10875.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Archease PF01951.16 KFP10876.1 - 7.6e-45 152.5 0.1 9e-45 152.3 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) BTB PF00651.31 KFP10877.1 - 8.7e-26 90.3 0.5 1.8e-25 89.4 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP10877.1 - 1e-08 35.2 2.6 1e-08 35.2 2.6 3.8 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.8 KFP10877.1 - 1.6e-05 25.0 0.1 3.6e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFP10877.1 - 0.00026 21.3 1.5 0.00026 21.3 1.5 3.9 5 0 0 5 5 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP10877.1 - 0.00084 19.0 3.6 0.00084 19.0 3.6 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 KFP10877.1 - 0.0016 18.8 2.2 0.06 13.8 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP10877.1 - 0.0023 18.6 1.2 0.0023 18.6 1.2 4.0 4 0 0 4 4 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP10877.1 - 0.019 15.1 0.8 0.019 15.1 0.8 3.2 3 0 0 3 3 3 0 Zinc ribbon domain BTB_2 PF02214.22 KFP10877.1 - 0.027 14.8 0.3 0.065 13.6 0.0 1.8 2 0 0 2 2 1 0 BTB/POZ domain zf-C2H2_jaz PF12171.8 KFP10877.1 - 0.038 14.3 1.5 0.76 10.1 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3212 PF11486.8 KFP10877.1 - 0.058 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) Trm112p PF03966.16 KFP10877.1 - 0.067 13.8 1.8 0.21 12.2 1.8 1.8 1 0 0 1 1 1 0 Trm112p-like protein Prim_Zn_Ribbon PF08273.12 KFP10877.1 - 0.12 12.6 0.4 0.12 12.6 0.4 2.2 2 0 0 2 2 1 0 Zinc-binding domain of primase-helicase PHF5 PF03660.14 KFP10877.1 - 0.37 11.0 6.5 6.2 7.1 0.9 2.6 1 1 0 2 2 2 0 PHF5-like protein zf-Di19 PF05605.12 KFP10877.1 - 0.39 11.0 11.0 0.24 11.7 6.9 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_10 PF10058.9 KFP10877.1 - 3.7 7.3 10.6 4.6 7.0 1.7 2.9 3 0 0 3 3 2 0 Predicted integral membrane zinc-ribbon metal-binding protein BTB PF00651.31 KFP10879.1 - 9.5e-27 93.4 0.3 1.5e-26 92.8 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP10879.1 - 1.3e-08 34.9 2.4 1.3e-08 34.9 2.4 3.8 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.8 KFP10879.1 - 5.2e-06 26.6 0.1 1.4e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.26 KFP10879.1 - 0.00018 21.8 1.7 0.00018 21.8 1.7 3.8 4 0 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP10879.1 - 0.00022 20.9 2.9 0.00022 20.9 2.9 2.5 4 0 0 4 4 3 1 C2H2-type zinc-finger domain BTB_2 PF02214.22 KFP10879.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP10879.1 - 0.0021 18.8 1.5 0.0021 18.8 1.5 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KFP10879.1 - 0.012 16.0 2.4 0.17 12.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP10879.1 - 7.9 6.9 13.3 0.42 11.0 6.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFP10879.1 - 9.3 6.4 9.2 6.6 6.9 6.4 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KFP10879.1 - 9.7 6.8 13.1 13 6.3 11.8 2.0 1 1 0 1 1 1 0 CHY zinc finger BTB PF00651.31 KFP10880.1 - 3.9e-26 91.5 0.2 7e-26 90.6 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP10880.1 - 1.4e-05 25.3 1.4 1.4e-05 25.3 1.4 3.8 4 0 0 4 4 4 1 Zinc finger, C2H2 type DUF3342 PF11822.8 KFP10880.1 - 1.8e-05 24.8 0.0 5.4e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_4 PF13894.6 KFP10880.1 - 0.0046 17.7 1.4 0.0046 17.7 1.4 4.3 5 0 0 5 5 5 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP10880.1 - 0.01 16.2 12.3 0.13 12.8 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KFP10880.1 - 0.021 15.2 0.1 0.021 15.2 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Herpes_ori_bp PF02399.15 KFP10880.1 - 0.077 11.0 0.4 0.14 10.2 0.4 1.3 1 0 0 1 1 1 0 Origin of replication binding protein Zn-ribbon_8 PF09723.10 KFP10880.1 - 5.4 7.2 8.9 0.47 10.6 0.5 2.9 2 1 0 2 2 2 0 Zinc ribbon domain BSD PF03909.17 KFP10881.1 - 2.6e-18 65.8 0.3 4.1e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 BSD domain Arm PF00514.23 KFP10882.1 - 3.1e-90 293.8 21.9 1.2e-13 50.5 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP10882.1 - 4.4e-25 88.0 1.5 4.4e-25 88.0 1.5 1.8 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 KFP10882.1 - 1.1e-22 79.3 3.0 2.1e-22 78.4 1.9 2.1 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_2 PF13646.6 KFP10882.1 - 3.8e-21 75.3 0.0 2.5e-07 31.0 0.0 5.0 3 2 2 5 5 4 4 HEAT repeats HEAT_EZ PF13513.6 KFP10882.1 - 7e-21 74.3 6.2 7.2e-07 29.6 0.0 6.2 5 2 2 7 7 7 3 HEAT-like repeat HEAT PF02985.22 KFP10882.1 - 8.6e-14 50.5 8.3 0.0031 17.6 0.0 7.8 9 0 0 9 9 9 2 HEAT repeat V-ATPase_H_C PF11698.8 KFP10882.1 - 3.6e-06 27.1 0.0 0.24 11.5 0.0 4.3 3 2 1 4 4 4 2 V-ATPase subunit H RICTOR_V PF14668.6 KFP10882.1 - 4.7e-06 26.7 1.4 0.71 10.1 0.0 4.8 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KFP10882.1 - 1.5e-05 24.6 0.1 0.1 12.1 0.0 2.8 1 1 1 2 2 2 2 Armadillo-like HEAT_PBS PF03130.16 KFP10882.1 - 0.00052 20.4 0.2 8.7 7.3 0.0 4.9 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat CTNNBL PF08216.11 KFP10882.1 - 0.014 15.6 0.0 3.2 8.0 0.0 3.9 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear SEN1_N PF12726.7 KFP10882.1 - 0.039 12.2 0.0 4.6 5.3 0.0 2.7 2 1 1 3 3 3 0 SEN1 N terminal NUSAP PF16006.5 KFP10882.1 - 1.5 8.5 6.1 2.1 8.0 6.1 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein PAH PF02671.21 KFP10882.1 - 5.7 7.2 5.5 1.3 9.2 0.7 2.5 2 1 1 3 3 3 0 Paired amphipathic helix repeat Taxilin PF09728.9 KFP10883.1 - 1e-116 389.5 79.7 1.1e-116 389.3 79.7 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HOOK PF05622.12 KFP10883.1 - 1.4 7.0 67.2 0.31 9.1 60.8 2.8 1 1 1 2 2 2 0 HOOK protein Phage_GPL PF05926.11 KFP10883.1 - 1.9 8.5 11.5 0.12 12.4 3.2 2.8 2 2 0 2 2 2 0 Phage head completion protein (GPL) FlaC_arch PF05377.11 KFP10883.1 - 5.5 7.5 28.1 0.19 12.2 1.0 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) IQ PF00612.27 KFP10884.1 - 0.12 12.3 0.5 0.12 12.3 0.5 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif DCX PF03607.17 KFP10885.1 - 3.7e-22 78.2 0.0 4.6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Doublecortin DCX PF03607.17 KFP10886.1 - 4.7e-15 55.4 0.0 6.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Doublecortin WD40 PF00400.32 KFP10887.1 - 1.9e-26 91.8 2.5 1.4e-06 28.9 2.6 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10887.1 - 5.1e-12 45.9 0.0 0.15 12.3 0.0 5.1 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP10887.1 - 0.0008 18.5 0.4 0.62 9.0 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ISN1 PF06437.11 KFP10887.1 - 0.0063 15.5 0.1 0.69 8.7 0.0 2.0 2 0 0 2 2 2 2 IMP-specific 5'-nucleotidase Nup160 PF11715.8 KFP10887.1 - 0.026 13.2 0.3 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 KFP10888.1 - 9.9e-97 323.3 0.0 1.2e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP10888.1 - 2.4e-50 171.3 0.0 3.1e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 KFP10888.1 - 5.8e-15 54.6 0.1 1.4e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH2 PF00017.24 KFP10888.1 - 6.6e-14 51.8 0.6 2e-12 47.0 0.6 2.4 1 1 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP10888.1 - 4.3e-10 39.3 0.0 9e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP10888.1 - 6.3e-08 32.2 0.0 1.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP10888.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP10888.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.11 KFP10888.1 - 0.071 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Hist_deacetyl PF00850.19 KFP10889.1 - 1.5e-85 287.4 0.1 2.3e-85 286.7 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Tmp39 PF10271.9 KFP10890.1 - 4.4e-210 698.1 19.1 5.1e-210 698.0 19.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein Sam68-YY PF16568.5 KFP10891.1 - 2.7e-15 56.8 36.2 4.8e-15 56.1 36.2 1.4 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFP10891.1 - 2.5e-11 43.2 0.0 4.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Qua1 PF16274.5 KFP10891.1 - 1.2e-10 41.1 0.6 1.2e-10 41.1 0.6 1.9 2 0 0 2 2 2 1 Qua1 domain KH_5 PF13184.6 KFP10891.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 NusA-like KH domain VIR_N PF15912.5 KFP10891.1 - 1.5 8.3 5.7 3.5 7.1 4.5 1.9 2 0 0 2 2 2 0 Virilizer, N-terminal Y_phosphatase PF00102.27 KFP10892.1 - 1.2e-07 31.6 0.0 3.8e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP10892.1 - 2e-07 30.9 0.0 3.2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP10892.1 - 0.18 11.8 0.2 0.33 10.9 0.2 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family AMP-binding PF00501.28 KFP10893.1 - 7e-97 324.7 0.0 7.3e-74 248.9 0.0 2.6 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFP10893.1 - 8.3e-06 26.6 0.2 1.5e-05 25.8 0.2 1.4 1 0 0 1 1 1 1 DMAP1-binding Domain Bromodomain PF00439.25 KFP10894.1 - 1.4e-10 41.1 0.9 2.6e-10 40.2 0.2 1.9 2 0 0 2 2 2 1 Bromodomain PWWP PF00855.17 KFP10894.1 - 3.9e-10 40.0 0.3 3.9e-10 40.0 0.3 3.7 3 1 0 3 3 3 1 PWWP domain zf-MYND PF01753.18 KFP10894.1 - 0.016 15.3 22.1 0.016 15.3 22.1 4.0 3 1 0 3 3 3 0 MYND finger 7tm_2 PF00002.24 KFP10895.1 - 1.8e-86 289.4 12.2 2.3e-86 289.1 12.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP10895.1 - 2e-21 76.0 2.7 2e-21 76.0 2.7 2.2 2 0 0 2 2 2 1 Hormone receptor domain DUF1129 PF06570.11 KFP10895.1 - 0.21 11.0 1.3 0.69 9.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) WD40 PF00400.32 KFP10896.1 - 4.3e-05 24.2 0.9 0.0045 17.8 0.3 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10896.1 - 0.074 13.4 0.0 4.2 7.7 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SMP_LBD PF17047.5 KFP10897.1 - 3.5e-121 401.3 0.7 5.3e-121 400.7 0.7 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KFP10897.1 - 3.1e-53 178.4 0.0 5.8e-21 74.7 0.0 3.7 3 0 0 3 3 3 3 C2 domain Condensin2nSMC PF12422.8 KFP10898.1 - 9.8e-57 191.3 1.5 9.8e-57 191.3 1.5 3.9 3 1 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 KFP10898.1 - 7.6e-09 35.1 0.1 2.2 8.7 0.0 5.5 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 KFP10898.1 - 1.6e-05 25.0 2.5 0.026 14.6 0.0 4.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP10898.1 - 0.00029 21.2 0.0 0.59 10.6 0.0 3.2 1 1 2 3 3 3 2 HEAT repeats Adaptin_N PF01602.20 KFP10898.1 - 0.0011 17.6 0.2 0.0011 17.6 0.2 2.0 2 1 0 2 2 2 1 Adaptin N terminal region DUF577 PF04510.12 KFP10898.1 - 0.0012 18.8 2.9 0.27 11.1 0.0 4.3 4 0 0 4 4 4 1 Family of unknown function (DUF577) DUF5389 PF17364.2 KFP10898.1 - 0.02 14.9 0.0 0.077 13.0 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5389) TIP120 PF08623.10 KFP10898.1 - 0.03 14.1 2.8 0.076 12.8 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.7 KFP10898.1 - 0.046 14.3 0.0 1 10.0 0.0 3.4 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF3517 PF12030.8 KFP10898.1 - 0.051 12.5 0.8 0.29 10.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) Ig_3 PF13927.6 KFP10899.1 - 4.1e-74 245.2 11.0 2.4e-14 53.7 0.1 7.1 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFP10899.1 - 1.4e-62 207.8 0.1 5.2e-13 48.9 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP10899.1 - 1.5e-52 175.9 6.0 8.1e-09 35.7 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFP10899.1 - 4.2e-49 164.7 3.0 3.6e-10 39.9 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain MAM PF00629.23 KFP10899.1 - 5.1e-39 133.8 0.0 1.1e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu V-set PF07686.17 KFP10899.1 - 2.8e-18 66.1 24.7 0.01 16.0 0.3 11.6 8 6 2 10 10 10 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP10899.1 - 1.3e-13 50.8 2.8 0.0019 18.2 0.0 6.3 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP10899.1 - 8e-08 32.4 0.1 2.8 8.3 0.0 6.1 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP10899.1 - 1.1e-06 28.1 1.3 0.52 9.9 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP10899.1 - 1.1e-05 25.4 0.1 2.1 8.5 0.0 5.0 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP10899.1 - 0.00034 20.9 0.1 0.68 10.3 0.0 4.7 5 0 0 5 5 5 1 Immunoglobulin C1-set domain BiPBP_C PF06832.12 KFP10899.1 - 0.023 14.8 0.0 0.097 12.7 0.0 2.1 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Marek_A PF02124.15 KFP10899.1 - 0.033 14.0 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 Marek's disease glycoprotein A LRR_4 PF12799.7 KFP10905.1 - 2.8e-15 56.2 14.4 4.1e-07 30.2 1.5 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP10905.1 - 4.3e-15 55.2 13.6 8.5e-07 28.7 1.8 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KFP10905.1 - 0.00056 19.7 8.1 0.4 10.9 0.2 4.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KFP10905.1 - 0.022 15.2 24.9 0.43 11.3 0.0 7.4 7 1 0 7 7 7 0 Leucine Rich Repeat zf-RING_14 PF17978.1 KFP10906.1 - 0.099 13.1 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DNA_pol_E_B PF04042.16 KFP10907.1 - 5.4e-52 176.2 0.7 7.9e-52 175.7 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 KFP10907.1 - 4.1e-18 65.5 0.5 7.7e-18 64.6 0.5 1.5 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Kelch_4 PF13418.6 KFP10908.1 - 6.9e-27 93.2 18.7 1.1e-07 31.8 0.4 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP10908.1 - 6.4e-25 86.9 14.5 4.1e-08 33.3 0.1 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFP10908.1 - 1.4e-23 82.3 19.6 5.4e-06 26.5 0.3 6.7 3 2 3 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KFP10908.1 - 6.3e-19 67.3 10.8 7e-06 25.5 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFP10908.1 - 1.1e-17 63.2 17.6 2.1e-06 27.5 0.0 6.1 5 2 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP10908.1 - 3.1e-17 62.2 6.7 0.00082 19.3 0.1 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFP10909.1 - 1.8e-25 88.5 14.3 1.5e-05 24.9 0.1 7.3 7 1 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 KFP10909.1 - 1.6e-24 85.6 23.7 2.4e-09 37.1 0.1 7.6 5 2 2 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KFP10909.1 - 9.4e-24 82.7 16.3 1.1e-06 28.1 0.3 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KFP10909.1 - 5.6e-19 68.0 17.8 4.3e-07 30.1 0.2 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFP10909.1 - 5.9e-18 64.5 15.3 4.8e-06 26.6 0.1 6.3 6 1 1 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KFP10909.1 - 1.3e-15 56.6 15.5 0.00019 21.3 0.0 7.0 6 2 0 6 6 6 5 Kelch motif DUF4462 PF14692.6 KFP10910.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) FbpA PF05833.11 KFP10911.1 - 3.5e-34 118.4 23.5 1e-33 116.8 23.4 1.9 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KFP10911.1 - 9.3e-34 116.4 0.6 1.2e-32 112.8 0.0 2.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KFP10911.1 - 2.4e-11 43.5 0.0 2.4e-11 43.5 0.0 3.8 5 1 0 5 5 5 1 NFACT protein C-terminal domain Rubella_Capsid PF05750.11 KFP10911.1 - 0.67 9.5 5.1 1.7 8.2 5.1 1.6 1 0 0 1 1 1 0 Rubella capsid protein TetR_C_21 PF17926.1 KFP10911.1 - 1.3 9.1 6.0 0.65 10.2 1.2 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF948 PF06103.11 KFP10911.1 - 3.4 8.0 4.9 2.3 8.5 1.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Arf PF00025.21 KFP10912.1 - 4e-77 257.6 0.0 4.5e-77 257.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP10912.1 - 3e-15 56.5 0.0 4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP10912.1 - 1.9e-14 53.6 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP10912.1 - 3e-13 49.6 0.0 3.7e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP10912.1 - 2e-12 46.9 1.0 4e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP10912.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP10912.1 - 9.5e-05 22.5 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFP10912.1 - 0.01 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SpoOE-like PF09388.10 KFP10912.1 - 0.021 14.7 1.2 0.038 13.9 1.2 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein CRISPR_Cas2 PF09827.9 KFP10912.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Methyltransf_16 PF10294.9 KFP10913.1 - 1.4e-28 99.8 0.0 1.6e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP10913.1 - 0.036 13.9 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain RasGEF PF00617.19 KFP10914.1 - 6.6e-50 169.8 0.4 1.4e-49 168.7 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFP10914.1 - 1.7e-31 108.5 0.3 1e-30 106.1 0.1 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif RhoGEF PF00621.20 KFP10914.1 - 1.7e-12 47.9 0.5 1.7e-12 47.9 0.5 2.7 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFP10914.1 - 4.4e-11 43.2 2.1 8.7e-11 42.3 0.1 2.5 3 0 0 3 3 3 1 PH domain Histone PF00125.24 KFP10914.1 - 5.6e-10 39.7 0.0 1.4e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 IQ_SEC7_PH PF16453.5 KFP10914.1 - 0.00017 21.5 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFP10914.1 - 0.0043 16.9 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 KFP10914.1 - 0.017 15.4 0.2 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 KFP10914.1 - 0.055 13.8 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DAO PF01266.24 KFP10915.1 - 7e-56 190.3 0.0 9.8e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase LRR_4 PF12799.7 KFP10916.1 - 0.081 13.4 3.3 0.16 12.5 1.0 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KFP10917.1 - 2.5e-62 210.7 0.0 2.9e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10917.1 - 1e-26 93.8 0.1 8.2e-26 90.8 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP10917.1 - 0.0002 20.4 0.0 0.00027 20.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP10917.1 - 0.066 13.1 0.2 0.34 10.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFP10917.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CNH PF00780.22 KFP10918.1 - 1.1e-76 258.1 0.8 2e-76 257.2 0.8 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP10918.1 - 1.1e-55 188.9 0.0 1.7e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10918.1 - 1.9e-34 119.1 0.0 3.7e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP10918.1 - 9.6e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP10918.1 - 0.008 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GBP PF02263.19 KFP10919.1 - 3.1e-101 338.0 0.1 4.1e-101 337.6 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 KFP10919.1 - 3.5e-06 26.7 0.1 5.4e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tiam_CC_Ex PF18385.1 KFP10919.1 - 0.0065 16.8 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain WW PF00397.26 KFP10921.1 - 2.9e-14 52.9 14.4 5.1e-10 39.3 4.3 3.5 3 0 0 3 3 3 2 WW domain Suppressor_APC PF11414.8 KFP10921.1 - 0.62 10.2 6.4 0.97 9.5 2.8 2.4 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein BST2 PF16716.5 KFP10922.1 - 0.0015 19.1 8.3 0.002 18.7 8.3 1.1 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 UPF0240 PF06784.11 KFP10922.1 - 0.026 14.6 4.3 0.032 14.3 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) GAS PF13851.6 KFP10922.1 - 0.035 13.5 14.6 0.49 9.7 7.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ISG65-75 PF11727.8 KFP10922.1 - 0.058 12.6 5.2 0.064 12.5 5.2 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein TMEM237 PF15383.6 KFP10922.1 - 0.079 12.1 0.8 0.08 12.0 0.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 Jnk-SapK_ap_N PF09744.9 KFP10922.1 - 0.32 11.2 12.0 1.4 9.1 2.4 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KIAA1430 PF13879.6 KFP10922.1 - 0.55 11.0 10.6 2 9.2 10.6 1.9 1 1 0 1 1 1 0 KIAA1430 homologue XhlA PF10779.9 KFP10922.1 - 0.85 9.9 10.5 3.7 7.8 0.7 2.6 2 1 1 3 3 3 0 Haemolysin XhlA GTP-bdg_M PF16360.5 KFP10922.1 - 1.5 9.4 7.4 0.56 10.9 1.0 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF1664 PF07889.12 KFP10922.1 - 1.9 8.5 7.3 4.1 7.5 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KFP10922.1 - 6.5 7.5 11.6 11 6.7 11.6 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Occludin_ELL PF07303.13 KFP10922.1 - 7.4 7.4 11.2 7.8 7.3 6.2 2.0 1 1 1 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 KFP10923.1 - 0.048 13.7 0.0 0.048 13.7 0.0 6.8 4 3 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DoxA PF07680.11 KFP10923.1 - 0.081 12.8 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 TQO small subunit DoxA Hydrolase_4 PF12146.8 KFP10924.1 - 0.00082 18.7 0.2 0.012 14.9 0.0 2.4 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFP10924.1 - 0.11 12.3 0.0 17 5.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NeuB PF03102.14 KFP10925.1 - 2e-78 263.2 0.0 2.3e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 KFP10925.1 - 9.5e-06 26.2 0.1 1.9e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 SAF domain ChapFlgA PF13144.6 KFP10925.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Opiods_neuropep PF01160.18 KFP10925.1 - 0.6 10.2 0.0 0.6 10.2 0.0 2.9 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide zf-RING_11 PF17123.5 KFP10926.1 - 4.1e-08 32.8 6.0 9.6e-08 31.6 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFP10926.1 - 5.7e-08 33.0 4.3 5.7e-08 33.0 4.3 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KFP10926.1 - 6.9e-05 22.6 3.5 0.00013 21.7 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP10926.1 - 9.5e-05 22.2 4.5 0.00021 21.1 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP10926.1 - 0.00034 20.8 3.9 0.00034 20.8 3.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP10926.1 - 0.0087 16.0 3.1 0.019 14.9 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP10926.1 - 0.011 15.7 2.7 0.031 14.3 2.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFP10926.1 - 0.13 11.9 4.0 0.25 11.0 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFP10926.1 - 0.24 11.6 2.9 0.53 10.5 2.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFP10926.1 - 3.4 7.8 8.3 0.09 12.8 1.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SH2 PF00017.24 KFP10927.1 - 3.8e-18 65.4 0.1 5.3e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 SH2 domain RIO1 PF01163.22 KFP10930.1 - 5.2e-54 182.7 1.9 1.2e-53 181.5 1.9 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KFP10930.1 - 2.6e-24 85.3 1.0 7.2e-24 83.8 0.1 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KFP10930.1 - 1.2e-08 35.2 4.7 8.3e-05 22.6 1.8 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFP10930.1 - 1.5e-06 27.7 5.8 4.2e-06 26.3 2.7 2.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KFP10930.1 - 0.0043 16.7 0.1 0.0074 15.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.8 KFP10930.1 - 0.097 12.3 0.6 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 DHH PF01368.20 KFP10930.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 DHH family RGM_C PF06534.13 KFP10931.1 - 5.4e-70 234.4 0.0 7.6e-70 233.9 0.0 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 KFP10931.1 - 2.5e-62 209.9 1.2 3.6e-62 209.4 1.2 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus SNF2_N PF00176.23 KFP10932.1 - 2e-68 230.7 0.7 4.1e-68 229.7 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFP10932.1 - 3.7e-33 114.0 0.0 3.7e-33 114.0 0.0 5.3 4 1 0 4 4 4 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFP10932.1 - 9.1e-29 99.1 9.5 3.2e-18 65.4 0.1 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFP10932.1 - 3.2e-27 94.8 2.2 3.2e-27 94.8 2.2 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFP10932.1 - 6.7e-20 71.5 0.0 1.8e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CHDCT2 PF08074.11 KFP10932.1 - 0.015 15.5 0.0 0.015 15.5 0.0 2.9 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Glyco_transf_29 PF00777.18 KFP10936.1 - 3.3e-77 259.5 0.0 4.1e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) OATP PF03137.20 KFP10941.1 - 6.1e-27 94.1 0.2 6.1e-27 94.1 0.2 1.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Cu2_monoox_C PF03712.15 KFP10942.1 - 2.8e-44 150.4 0.2 4.8e-44 149.6 0.2 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFP10942.1 - 4e-25 88.5 0.0 8.7e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KFP10942.1 - 6.2e-19 67.0 8.3 2.6e-05 24.0 0.1 6.1 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 KFP10942.1 - 0.0068 16.0 0.0 2.8 7.4 0.0 2.8 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF2207 PF09972.9 KFP10942.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Integrase_H2C2 PF17921.1 KFP10943.1 - 1.1e-15 57.4 1.0 2.6e-15 56.2 1.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KFP10943.1 - 2.6e-08 34.1 0.1 2e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 KFP10943.1 - 4.8e-05 23.5 0.9 0.00012 22.2 0.9 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Pox_A3L PF05288.11 KFP10943.1 - 0.31 11.1 1.6 0.64 10.0 0.1 2.3 3 0 0 3 3 3 0 Poxvirus A3L Protein His_Phos_2 PF00328.22 KFP10944.1 - 3.4e-137 457.9 1.3 4.6e-137 457.5 1.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFP10944.1 - 9e-43 144.4 0.4 2.3e-42 143.1 0.4 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFP10944.1 - 0.0021 17.7 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain UNC119_bdg PF15435.6 KFP10945.1 - 9.4e-111 368.0 0.8 1.1e-110 367.9 0.8 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue PH PF00169.29 KFP10946.1 - 1.1e-29 103.1 0.9 2.5e-17 63.3 0.2 2.6 3 0 0 3 3 3 2 PH domain PDZ PF00595.24 KFP10946.1 - 3e-14 53.1 0.0 5.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP10946.1 - 2.3e-12 46.6 0.2 4e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFP10946.1 - 2.9e-10 40.5 11.8 0.00011 22.6 7.0 4.3 2 2 1 3 3 3 3 Pleckstrin homology domain PDZ_2 PF13180.6 KFP10946.1 - 2.9e-07 30.7 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_8 PF15409.6 KFP10946.1 - 6.9e-07 29.5 1.4 3e-05 24.2 1.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KFP10946.1 - 0.0089 16.4 0.6 5.4 7.4 0.1 3.5 2 2 1 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 KFP10946.1 - 0.012 15.7 0.2 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 PH domain PH_15 PF17339.2 KFP10946.1 - 0.1 12.5 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 PH domain NUDIX PF00293.28 KFP10947.1 - 4.2e-19 68.9 0.2 1.1e-17 64.3 0.0 2.8 3 1 0 3 3 3 1 NUDIX domain Ank_2 PF12796.7 KFP10947.1 - 9.1e-11 42.2 0.2 2.9e-10 40.6 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP10947.1 - 4.5e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.11 KFP10947.1 - 6.1e-08 32.2 0.6 1e-07 31.5 0.6 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 KFP10947.1 - 1.5e-07 32.0 0.0 3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank_4 PF13637.6 KFP10947.1 - 2.9e-07 30.9 0.6 1.4e-05 25.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP10947.1 - 2.2e-05 24.7 0.4 0.00015 22.0 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KFP10947.1 - 0.00027 21.1 0.7 0.0024 18.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat DNA_ligase_ZBD PF03119.16 KFP10947.1 - 0.2 11.7 0.8 0.54 10.3 0.8 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain RVT_1 PF00078.27 KFP10952.1 - 0.0028 17.2 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP10954.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ephrin PF00812.17 KFP10955.1 - 3.6e-32 111.2 0.1 4.6e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Ephrin LRR_6 PF13516.6 KFP10956.1 - 2.7e-14 51.9 8.8 0.067 13.3 0.0 10.3 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 KFP10956.1 - 6e-07 29.7 5.8 0.67 10.5 2.3 6.1 4 2 5 9 9 9 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFP10956.1 - 1.6e-06 27.9 2.9 1.6e-06 27.9 2.9 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFP10956.1 - 0.0033 17.3 5.6 0.0033 17.3 2.3 2.8 3 1 0 3 3 3 1 F-box domain DUF3885 PF13021.6 KFP10956.1 - 0.15 12.2 0.1 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) LRR_1 PF00560.33 KFP10956.1 - 3.2 8.7 8.7 1e+02 4.1 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 KFP10957.1 - 1.3e-102 342.5 0.2 5e-102 340.6 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 KFP10957.1 - 2.3e-50 171.4 0.0 9.3e-50 169.4 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP10957.1 - 1.1e-21 76.7 0.0 4e-21 74.9 0.0 2.1 1 0 0 1 1 1 1 SH2 domain FCH PF00611.23 KFP10957.1 - 1.8e-11 44.1 2.4 1.8e-11 44.1 2.4 3.2 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain ABC1 PF03109.16 KFP10957.1 - 0.56 10.4 4.7 1.2 9.3 0.0 3.7 4 0 0 4 4 4 0 ABC1 family zf-RING_2 PF13639.6 KFP10958.1 - 4.6e-10 39.7 15.0 1.2e-09 38.4 15.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFP10958.1 - 2.6e-06 27.2 11.5 7.6e-06 25.7 11.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP10958.1 - 1.5e-05 25.2 12.0 4e-05 23.8 12.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP10958.1 - 7.8e-05 22.3 9.9 0.00024 20.8 9.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP10958.1 - 0.00032 20.6 7.1 0.00032 20.6 7.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP10958.1 - 0.00036 20.3 14.9 0.00036 20.3 14.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP10958.1 - 0.0029 17.5 13.5 0.0068 16.3 13.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP10958.1 - 0.003 17.4 11.8 0.0065 16.3 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Amidase PF01425.21 KFP10958.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Amidase zf-ANAPC11 PF12861.7 KFP10958.1 - 0.011 15.8 7.0 0.024 14.7 7.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP10958.1 - 0.29 10.8 12.3 1.6 8.4 12.2 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mito_carr PF00153.27 KFP10960.1 - 6.1e-20 71.0 0.1 2e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Utp21 PF04192.12 KFP10961.1 - 2e-64 217.3 0.0 3.4e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFP10961.1 - 7.6e-19 67.7 16.4 1.6e-09 38.2 0.6 8.9 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10961.1 - 5.4e-11 42.7 0.3 0.0029 17.9 0.0 6.6 4 3 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFP10961.1 - 0.0022 18.3 0.6 0.0046 17.2 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family SGL PF08450.12 KFP10961.1 - 0.057 13.0 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 KFP10961.1 - 0.099 11.6 0.0 0.74 8.7 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 KFP10963.1 - 1.7e-46 158.7 0.0 1.9e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP10963.1 - 2.5e-15 56.5 0.0 2.8e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP10963.1 - 0.00028 20.3 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like START PF01852.19 KFP10964.1 - 1.6e-18 66.9 0.0 1.8e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 START domain Alveol-reg_P311 PF11092.8 KFP10966.1 - 1.2e-35 121.5 0.1 1.3e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) FERM_M PF00373.18 KFP10968.1 - 2.4e-19 69.8 1.2 4.6e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFP10968.1 - 3.8e-18 65.7 0.7 7.6e-18 64.7 0.7 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP10968.1 - 7.3e-15 54.7 0.0 1.7e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 KFP10968.1 - 2.2e-14 53.2 2.1 2.2e-14 53.2 2.1 3.4 4 0 0 4 4 4 1 FERM adjacent (FA) Arm_APC_u3 PF16629.5 KFP10969.1 - 3.9e-175 581.4 19.9 3.9e-175 581.4 19.9 3.8 3 0 0 3 3 3 1 Armadillo-associated region on APC APC_basic PF05956.11 KFP10969.1 - 2.3e-100 336.4 73.5 2.3e-100 336.4 73.5 8.9 10 1 0 10 10 4 1 APC basic domain EB1_binding PF05937.11 KFP10969.1 - 9.1e-93 309.7 21.8 9.1e-93 309.7 21.8 8.5 9 2 1 10 10 2 1 EB-1 Binding Domain APC_r PF05923.12 KFP10969.1 - 9.2e-72 235.5 45.2 1.6e-11 43.6 1.7 9.0 8 0 0 8 8 8 7 APC repeat APC_u5 PF16630.5 KFP10969.1 - 5.9e-54 181.3 6.9 5.9e-54 181.3 6.9 5.0 4 1 0 4 4 1 1 Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 PF16633.5 KFP10969.1 - 8.7e-43 145.3 10.6 8.7e-43 145.3 10.6 5.0 3 0 0 3 3 1 1 Unstructured region on APC between 1st two creatine-rich regions APC_u14 PF16635.5 KFP10969.1 - 1.6e-39 134.3 10.5 1.6e-39 134.3 10.5 4.7 5 0 0 5 5 1 1 Unstructured region on APC between SAMP and APC_crr APC_rep PF18797.1 KFP10969.1 - 1e-37 128.9 0.9 1e-37 128.9 0.9 4.5 5 0 0 5 5 2 1 Adenomatous polyposis coli (APC) repeat APC_u15 PF16636.5 KFP10969.1 - 4.2e-32 110.4 7.7 4.2e-32 110.4 7.7 8.0 9 1 0 9 9 4 1 Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC PF16689.5 KFP10969.1 - 1.8e-28 98.3 7.3 1.8e-28 98.3 7.3 3.9 4 0 0 4 4 3 1 Coiled-coil N-terminus of APC, dimerisation domain Arm PF00514.23 KFP10969.1 - 1.3e-27 95.0 14.1 9.1e-07 28.7 0.4 6.8 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat SAMP PF05924.11 KFP10969.1 - 1.8e-27 93.8 15.1 4.3e-10 38.5 1.8 3.9 3 0 0 3 3 3 3 SAMP Motif APC_u13 PF16634.5 KFP10969.1 - 1.7e-26 91.8 2.5 1.7e-26 91.8 2.5 3.0 2 0 0 2 2 2 1 Unstructured region on APC between APC_crr and SAMP APC_15aa PF05972.11 KFP10969.1 - 2.6e-22 77.6 28.4 5.1e-06 26.4 0.3 5.7 6 0 0 6 6 5 4 APC 15 residue motif Suppressor_APC PF11414.8 KFP10969.1 - 2e-21 75.8 4.5 2e-21 75.8 4.5 3.5 3 0 0 3 3 3 1 Adenomatous polyposis coli tumour suppressor protein JIP_LZII PF16471.5 KFP10969.1 - 0.065 13.4 10.8 0.069 13.3 3.3 3.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Sec7_N PF12783.7 KFP10969.1 - 0.18 11.7 0.1 0.42 10.5 0.1 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal bZIP_1 PF00170.21 KFP10969.1 - 0.2 11.8 3.2 1.4 9.0 3.2 2.6 1 0 0 1 1 1 0 bZIP transcription factor SRP19 PF01922.17 KFP10971.1 - 6.8e-26 91.1 0.0 8.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein TB2_DP1_HVA22 PF03134.19 KFP10972.1 - 1.3e-29 102.0 1.9 1.5e-29 101.7 1.9 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DCP2 PF05026.13 KFP10973.1 - 2.9e-24 85.2 0.1 8.6e-23 80.5 0.1 2.4 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 KFP10973.1 - 5.8e-16 58.7 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain MCC-bdg_PDZ PF10506.9 KFP10974.1 - 2.1e-43 146.2 21.4 5.8e-28 96.7 7.3 7.5 6 2 3 9 9 9 2 PDZ domain of MCC-2 bdg protein for Usher syndrome Spc7 PF08317.11 KFP10974.1 - 0.00028 19.9 2.9 0.00028 19.9 2.9 5.8 4 1 3 7 7 7 3 Spc7 kinetochore protein Mod_r PF07200.13 KFP10974.1 - 0.00029 21.0 0.6 0.00029 21.0 0.6 6.6 5 1 1 6 6 6 2 Modifier of rudimentary (Mod(r)) protein FAM76 PF16046.5 KFP10974.1 - 0.0036 16.7 4.4 0.0036 16.7 4.4 5.0 2 2 3 5 5 5 1 FAM76 protein APG6_N PF17675.1 KFP10974.1 - 0.014 15.9 4.6 0.014 15.9 4.6 7.7 3 2 4 7 7 7 0 Apg6 coiled-coil region SHE3 PF17078.5 KFP10974.1 - 0.017 14.8 1.7 0.017 14.8 1.7 6.2 4 1 1 5 5 5 0 SWI5-dependent HO expression protein 3 ERM PF00769.19 KFP10974.1 - 2.5 7.9 88.1 0.018 14.9 11.4 4.9 3 2 1 4 4 4 0 Ezrin/radixin/moesin family DUF1359 PF07097.11 KFP10974.1 - 4.4 7.6 6.5 13 6.1 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1359) Occludin_ELL PF07303.13 KFP10976.1 - 2.9e-30 104.9 10.3 2.9e-30 104.9 10.3 1.6 2 0 0 2 2 2 1 Occludin homology domain MARVEL PF01284.23 KFP10976.1 - 1.4e-16 60.9 10.8 1.8e-16 60.5 10.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Sec34 PF04136.15 KFP10976.1 - 0.0033 17.3 1.7 0.0038 17.1 0.2 1.8 2 0 0 2 2 2 1 Sec34-like family Tex_N PF09371.10 KFP10976.1 - 0.027 14.1 2.2 0.048 13.3 2.2 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF1241 PF06840.11 KFP10976.1 - 0.071 12.8 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Ssl1 PF04056.14 KFP10978.1 - 3.5e-89 297.7 0.1 4.8e-89 297.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KFP10978.1 - 5e-13 49.6 0.0 1.1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 KFP10978.1 - 2.9e-10 40.2 25.5 3.4e-09 36.8 18.7 2.9 2 1 0 2 2 2 2 TFIIH C1-like domain VWA PF00092.28 KFP10978.1 - 7.5e-05 23.0 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HscB_4_cys PF18256.1 KFP10978.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.5 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif IBR PF01485.21 KFP10978.1 - 0.12 12.6 17.1 0.066 13.4 9.3 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 KFP10978.1 - 3.7 7.4 23.0 5.6 6.9 14.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SMN PF06003.12 KFP10979.1 - 6e-125 415.8 6.9 6.8e-125 415.6 6.9 1.0 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFP10979.1 - 0.0014 18.6 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Tudor domain 4F5 PF04419.14 KFP10980.1 - 2.5e-08 34.7 8.5 2.5e-08 34.7 8.5 2.1 2 0 0 2 2 2 1 4F5 protein family Myb_DNA-bind_7 PF15963.5 KFP10981.1 - 8.6e-22 76.9 1.6 8.6e-22 76.9 1.6 3.1 3 1 1 4 4 4 1 Myb DNA-binding like CobT PF06213.12 KFP10981.1 - 5.5 6.3 22.6 4.1 6.7 9.2 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 KFP10981.1 - 5.7 7.4 15.8 6.9 7.2 1.4 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CNDH2_C PF16858.5 KFP10981.1 - 6.1 6.6 21.6 6.4 6.6 2.4 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CSRNP_N PF16019.5 KFP10981.1 - 9.1 6.1 16.5 6.9 6.5 9.5 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus PNP_UDP_1 PF01048.20 KFP10982.1 - 5.1e-47 160.1 0.0 5.6e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily RIG-I_C PF18119.1 KFP10984.1 - 4.3e-36 124.0 2.1 4.3e-36 124.0 2.1 2.2 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain RIG-I_C-RD PF11648.8 KFP10984.1 - 8e-33 113.1 5.0 8e-33 113.1 5.0 2.4 2 0 0 2 2 2 1 C-terminal domain of RIG-I CARD_2 PF16739.5 KFP10984.1 - 9.2e-21 73.6 0.2 9.2e-21 73.6 0.2 2.8 3 0 0 3 3 3 1 Caspase recruitment domain DEAD PF00270.29 KFP10984.1 - 3.4e-18 66.0 0.1 9.8e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFP10984.1 - 1.9e-17 63.8 1.4 1.8e-15 57.4 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP10984.1 - 1.5e-14 54.3 0.0 7.1e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_25 PF13481.6 KFP10984.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFP10984.1 - 0.024 15.0 1.7 0.21 11.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP10984.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFP10984.1 - 0.12 11.9 2.6 1.6 8.2 0.0 2.6 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1474 PF07342.11 KFP10984.1 - 0.6 10.7 4.1 8.9 6.9 0.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1474) Aconitase PF00330.20 KFP10985.1 - 1.5e-179 597.8 0.0 1.9e-179 597.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFP10985.1 - 3.8e-46 156.7 0.0 5.2e-45 153.0 0.0 2.2 2 0 0 2 2 2 1 Aconitase C-terminal domain DAGK_acc PF00609.19 KFP10986.1 - 4.1e-50 170.2 0.0 1.1e-49 168.8 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP10986.1 - 6.1e-23 80.8 0.0 1.5e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.23 KFP10986.1 - 8.7e-18 64.8 0.9 1.3e-10 41.7 0.2 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 KFP10986.1 - 1.7e-15 56.6 40.3 1.3e-11 44.2 5.7 3.8 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFP10986.1 - 0.011 16.0 4.0 0.011 16.0 4.0 3.9 3 1 1 4 4 4 0 C1 domain Aldo_ket_red PF00248.21 KFP10988.1 - 3.9e-54 183.9 0.0 7e-54 183.0 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Y_phosphatase PF00102.27 KFP10991.1 - 5.9e-84 281.3 1.6 1.7e-83 279.8 1.6 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 KFP10991.1 - 2.3e-28 98.4 19.9 1.9e-08 34.5 0.7 6.3 6 0 0 6 6 6 5 Fibronectin type III domain Y_phosphatase3 PF13350.6 KFP10991.1 - 7.4e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFP10991.1 - 0.00014 21.6 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP10991.1 - 0.00069 19.8 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 KFP10991.1 - 0.0035 17.9 12.7 0.84 10.2 0.5 4.5 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain SIT PF15330.6 KFP10991.1 - 4 7.9 6.2 1.2e+02 3.1 1.2 3.9 4 0 0 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT PTB PF08416.13 KFP10992.1 - 1.1e-53 180.8 1.4 2.4e-53 179.8 1.4 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SAM_3 PF18016.1 KFP10992.1 - 8e-23 80.0 0.0 1.9e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KFP10992.1 - 1e-09 37.9 0.1 2.3e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain PID PF00640.23 KFP10992.1 - 1.9e-06 27.9 1.9 2.8e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 KFP10992.1 - 3.2e-06 26.9 0.0 7.7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP10992.1 - 1.8e-05 24.3 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP10992.1 - 0.001 19.3 0.1 0.0027 17.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 KFP10992.1 - 0.0093 16.0 0.1 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain WD40 PF00400.32 KFP10993.1 - 8.4e-31 105.6 2.2 5.7e-10 39.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP10993.1 - 2.1e-08 34.4 0.0 0.15 12.4 0.0 4.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP10993.1 - 0.007 15.4 0.0 0.19 10.6 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP10993.1 - 0.025 13.9 0.0 0.26 10.6 0.1 2.2 1 1 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 KFP10993.1 - 0.03 12.9 0.1 0.78 8.2 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 KFP10993.1 - 0.049 12.5 0.2 1.7 7.5 0.1 2.8 2 2 1 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Frtz PF11768.8 KFP10993.1 - 0.062 11.6 0.0 4.8 5.4 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DeoC PF01791.9 KFP10994.1 - 1.8e-26 93.2 0.0 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PTR2 PF00854.21 KFP10995.1 - 9.4e-43 146.5 10.8 1.3e-42 146.0 10.8 1.1 1 0 0 1 1 1 1 POT family MAPEG PF01124.18 KFP10997.1 - 1.1e-25 90.0 0.8 1.3e-25 89.8 0.8 1.0 1 0 0 1 1 1 1 MAPEG family Anoctamin PF04547.12 KFP10997.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel LIM PF00412.22 KFP10998.1 - 4.1e-25 87.8 19.0 2e-15 56.7 8.1 2.0 2 0 0 2 2 2 2 LIM domain Siva PF05458.12 KFP10998.1 - 1.1 8.9 11.0 0.28 10.8 3.1 2.0 1 1 1 2 2 2 0 Cd27 binding protein (Siva) Ras PF00071.22 KFP11002.1 - 2.2e-19 69.6 0.0 3e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Ras family PI-PLC-X PF00388.19 KFP11005.1 - 2.6e-62 208.7 0.0 4.2e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP11005.1 - 6.5e-43 145.7 0.2 1.3e-42 144.7 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFP11005.1 - 1.5e-21 76.6 0.3 4.1e-21 75.3 0.3 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP11005.1 - 7.1e-15 55.2 0.0 1.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFP11005.1 - 0.0097 16.3 0.7 0.1 13.0 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair PH PF00169.29 KFP11008.1 - 3.2e-19 69.4 0.6 7.5e-18 65.0 0.1 3.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP11008.1 - 0.00071 20.0 5.5 0.017 15.5 5.5 3.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFP11008.1 - 0.003 17.6 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFP11008.1 - 0.058 13.8 0.2 1.1 9.6 0.2 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 KFP11008.1 - 0.084 13.2 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2 PF00096.26 KFP11010.1 - 6.6e-08 32.6 14.2 0.13 12.7 0.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11010.1 - 1.4e-05 25.5 13.9 0.11 13.3 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP11010.1 - 0.00044 20.5 0.0 0.00044 20.5 0.0 3.3 4 0 0 4 4 4 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 KFP11010.1 - 0.005 17.3 0.0 0.66 10.5 0.0 2.6 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain DUF4764 PF15961.5 KFP11010.1 - 0.007 15.1 0.3 0.0087 14.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 KFP11010.1 - 0.01 15.6 13.2 0.76 9.6 0.0 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KFP11010.1 - 0.17 12.0 2.0 3 7.9 0.0 2.4 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFP11010.1 - 0.25 11.6 3.5 3.3 8.1 0.3 2.4 1 1 3 4 4 4 0 C2H2-type zinc ribbon RVT_1 PF00078.27 KFP11012.1 - 0.0026 17.3 0.0 0.0064 16.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OATP PF03137.20 KFP11013.1 - 2.3e-168 560.9 12.5 3e-168 560.5 12.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFP11013.1 - 1.7e-20 73.3 15.4 2.6e-16 59.5 1.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.15 KFP11013.1 - 7.8e-11 41.9 9.6 2e-10 40.6 9.6 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP11013.1 - 3.8e-05 23.6 3.5 0.00011 22.2 3.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.20 KFP11015.1 - 1.6e-164 548.2 17.6 1.8e-164 548.1 17.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFP11015.1 - 8.1e-22 77.6 28.6 8.5e-20 71.0 9.8 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFP11015.1 - 7.9e-12 45.1 7.1 1.9e-11 43.9 7.1 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP11015.1 - 0.0038 17.2 5.3 0.0093 16.0 5.3 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain TauE PF01925.19 KFP11015.1 - 2.2 7.8 20.8 0.22 11.1 1.4 3.8 4 0 0 4 4 4 0 Sulfite exporter TauE/SafE Calc_CGRP_IAPP PF00214.19 KFP11016.1 - 4.6e-29 101.2 0.1 5.3e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family Pyr_redox_2 PF07992.14 KFP11017.1 - 2.3e-23 82.9 0.0 1.5e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KFP11017.1 - 1.1e-07 31.7 0.5 6.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 KFP11017.1 - 0.0069 15.7 0.3 0.5 9.6 0.0 3.2 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.31 KFP11018.1 - 9.1e-18 64.6 0.0 5.4e-16 58.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP11018.1 - 5.3e-17 62.1 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFP11018.1 - 4.4e-13 49.8 5.8 1.9e-12 47.7 5.8 2.2 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFP11018.1 - 0.00019 21.5 0.0 0.00063 19.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RQC PF09382.10 KFP11018.1 - 0.00027 20.7 0.0 0.0041 16.9 0.0 2.7 1 1 0 1 1 1 1 RQC domain KOW PF00467.29 KFP11018.1 - 0.058 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 KOW motif NinF PF05810.12 KFP11018.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.2 2 0 0 2 2 2 0 NinF protein Osmo_CC PF08946.10 KFP11018.1 - 2.4 8.5 4.9 6.8 7.0 4.9 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Got1 PF04178.12 KFP11019.1 - 1e-17 64.6 16.1 1.2e-17 64.3 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Ac81 PF05820.11 KFP11019.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 Fzo_mitofusin PF04799.13 KFP11019.1 - 0.27 10.8 0.0 0.37 10.3 0.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF3185 PF11381.8 KFP11019.1 - 2.5 8.2 15.6 0.29 11.2 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Aminotran_4 PF01063.19 KFP11020.1 - 1.3e-33 116.8 0.0 1.6e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HMG_box PF00505.19 KFP11022.1 - 2.5e-22 79.1 3.8 2.5e-22 79.1 3.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP11022.1 - 5.7e-09 36.4 1.1 5.7e-09 36.4 1.1 3.5 4 0 0 4 4 4 1 HMG-box domain DUF2347 PF09804.9 KFP11022.1 - 0.055 13.1 0.3 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) MPS2 PF17060.5 KFP11022.1 - 0.81 8.9 9.5 1.7 7.9 9.5 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 Prominin PF05478.11 KFP11022.1 - 1.1 7.1 5.1 1.9 6.4 5.1 1.3 1 0 0 1 1 1 0 Prominin DivIVA PF05103.13 KFP11022.1 - 1.4 9.0 18.0 0.55 10.3 12.8 2.4 2 0 0 2 2 2 0 DivIVA protein AAA_23 PF13476.6 KFP11022.1 - 7.8 6.9 15.7 44 4.5 13.2 2.5 2 0 0 2 2 2 0 AAA domain Choline_kinase PF01633.20 KFP11025.1 - 1e-62 211.5 0.1 1.6e-62 210.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFP11025.1 - 9.2e-14 51.9 0.0 1.4e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP11025.1 - 0.00017 21.0 0.6 0.00024 20.5 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase C2 PF00168.30 KFP11026.1 - 3.8e-15 56.0 0.0 7.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 KFP11026.1 - 0.00017 22.2 5.1 0.028 15.1 0.0 4.7 4 1 0 4 4 4 1 Putative heavy-metal-binding Glyco_transf_29 PF00777.18 KFP11027.1 - 1.7e-78 263.8 0.0 1.9e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Flavi_glycop_C PF02832.16 KFP11027.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Sulfotransfer_1 PF00685.27 KFP11029.1 - 7.6e-68 228.9 3.7 3.6e-65 220.1 3.7 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11029.1 - 0.00017 22.0 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family CTP_transf_3 PF02348.19 KFP11030.1 - 1.4e-34 119.9 0.0 2e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Hydrolase_3 PF08282.12 KFP11030.1 - 4.6e-06 26.5 0.4 8.8e-05 22.4 0.0 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP11030.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_membrane PF00664.23 KFP11031.1 - 1.1e-64 218.8 26.8 2.8e-32 112.5 4.9 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP11031.1 - 2.8e-52 176.9 0.2 1.3e-24 87.3 0.0 3.3 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.19 KFP11031.1 - 3e-07 30.1 7.2 0.024 14.1 0.1 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFP11031.1 - 8.9e-06 25.7 2.2 1.1 8.9 0.1 3.7 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP11031.1 - 2.5e-05 24.2 0.1 0.023 14.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFP11031.1 - 0.00016 21.3 1.5 0.079 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFP11031.1 - 0.0015 18.6 0.1 1.7 8.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP11031.1 - 0.0043 17.3 0.1 2.1 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KFP11031.1 - 0.0058 16.4 0.2 5.3 6.7 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFP11031.1 - 0.013 14.8 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFP11031.1 - 0.014 14.9 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 KFP11031.1 - 0.016 14.0 0.8 7.3 5.3 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 KFP11031.1 - 0.021 15.2 0.1 0.6 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KFP11031.1 - 0.032 13.8 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFP11031.1 - 0.044 12.9 0.0 4.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP11031.1 - 0.072 12.8 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFP11031.1 - 0.072 12.8 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KFP11031.1 - 0.29 10.4 1.2 10 5.4 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA_15 PF13175.6 KFP11031.1 - 0.32 10.7 2.9 3.2 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 KFP11031.1 - 0.55 10.3 2.7 1.9 8.6 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 KFP11031.1 - 0.8 10.2 13.2 15 6.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain IRK_C PF17655.1 KFP11032.1 - 2.2e-71 239.0 0.0 3.1e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP11032.1 - 6e-59 197.9 4.5 8.8e-59 197.4 4.5 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DOR PF14839.6 KFP11032.1 - 0.12 12.3 1.2 0.19 11.7 1.2 1.2 1 0 0 1 1 1 0 DOR family EI24 PF07264.11 KFP11032.1 - 0.12 12.6 3.6 0.19 11.9 3.6 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Ldh_1_N PF00056.23 KFP11033.1 - 1.1e-41 142.2 0.1 1.7e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFP11033.1 - 2.1e-21 76.6 0.0 3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KFP11033.1 - 0.00031 20.4 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glycogen_syn PF05693.13 KFP11035.1 - 0 1166.7 0.0 0 1166.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KFP11035.1 - 2.3e-05 24.0 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFP11035.1 - 2.9e-05 24.1 0.1 6.1e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFP11035.1 - 3.4e-05 24.3 0.0 0.0058 17.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Spexin PF15171.6 KFP11036.1 - 2.2e-45 152.7 0.8 2.2e-45 152.7 0.8 1.4 2 0 0 2 2 2 1 Neuropeptide secretory protein family, NPQ, spexin MRVI1 PF05781.12 KFP11038.1 - 1.7e-148 495.6 9.8 1.9e-148 495.5 9.8 1.0 1 0 0 1 1 1 1 MRVI1 protein KorB PF08535.10 KFP11038.1 - 0.029 14.4 0.2 0.067 13.2 0.2 1.7 1 0 0 1 1 1 0 KorB domain DUF919 PF06034.11 KFP11038.1 - 0.54 10.1 4.9 0.35 10.7 2.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Fib_alpha PF08702.10 KFP11038.1 - 0.73 10.0 6.4 1.5 9.0 6.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Casc1_N PF15927.5 KFP11039.1 - 1.5e-59 201.1 14.8 1.5e-59 201.1 14.8 2.4 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus PYC_OADA PF02436.18 KFP11039.1 - 8.2 6.1 7.5 0.97 9.1 0.5 2.6 2 0 0 2 2 2 0 Conserved carboxylase domain Complex1_LYR PF05347.15 KFP11040.1 - 1.9e-15 56.7 0.1 2.9e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP11040.1 - 5.9e-08 33.3 0.6 7.9e-08 32.9 0.6 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Ras PF00071.22 KFP11041.1 - 1.3e-58 197.2 0.0 1.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11041.1 - 6.5e-22 78.0 0.0 1.3e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11041.1 - 9.5e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP11041.1 - 2.4e-07 30.5 0.5 2.3e-06 27.3 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP11041.1 - 2.5e-06 27.5 0.0 0.017 15.1 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP11041.1 - 1.2e-05 25.4 0.1 3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 KFP11041.1 - 0.0015 17.6 0.2 0.022 13.7 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 KFP11041.1 - 0.0023 17.2 0.3 0.091 11.9 0.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 KFP11041.1 - 0.0024 17.4 0.0 0.022 14.3 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KFP11041.1 - 0.019 14.8 0.7 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KFP11041.1 - 0.024 13.9 0.3 0.054 12.8 0.0 1.9 2 1 0 2 2 2 0 Septin AAA_25 PF13481.6 KFP11041.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.7 2 1 1 3 3 3 0 AAA domain CD20 PF04103.15 KFP11043.1 - 3.8e-24 85.5 15.4 5e-24 85.2 15.4 1.1 1 0 0 1 1 1 1 CD20-like family TcpE PF12648.7 KFP11043.1 - 0.79 10.3 10.0 0.045 14.3 2.6 2.2 2 1 0 2 2 2 0 TcpE family DUF2371 PF10177.9 KFP11043.1 - 3.2 7.9 5.7 14 5.9 0.8 3.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) MIR PF02815.19 KFP11044.1 - 2.6e-70 236.1 1.5 3.5e-67 225.9 0.1 3.0 2 0 0 2 2 2 2 MIR domain RYDR_ITPR PF01365.21 KFP11044.1 - 2.5e-69 232.8 28.9 3.2e-60 203.0 1.3 4.9 5 1 0 5 5 5 2 RIH domain Ins145_P3_rec PF08709.11 KFP11044.1 - 3.5e-66 222.4 0.5 3.2e-65 219.3 0.5 2.4 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 KFP11044.1 - 3.9e-33 113.3 27.7 1e-31 108.8 4.8 5.2 5 0 0 5 5 5 2 RyR and IP3R Homology associated Ion_trans PF00520.31 KFP11044.1 - 6.6e-17 61.6 11.2 2.1e-16 59.9 11.2 1.9 1 0 0 1 1 1 1 Ion transport protein DUF2207 PF09972.9 KFP11044.1 - 0.035 12.9 0.6 1.6 7.4 0.0 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sec2p PF06428.11 KFP11044.1 - 0.072 13.1 6.3 0.38 10.8 6.3 2.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p a_DG1_N2 PF18424.1 KFP11046.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-Dystroglycan N-terminal domain 2 DUF2151 PF10221.9 KFP11047.1 - 4.8e-303 1007.1 5.0 5.5e-303 1006.9 5.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator Plk4_PB2 PF18409.1 KFP11047.1 - 0.065 13.9 0.1 0.63 10.8 0.1 2.6 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 SIKE PF05769.11 KFP11048.1 - 7.8e-74 247.5 26.8 9.1e-74 247.3 26.8 1.0 1 0 0 1 1 1 1 SIKE family Tho2 PF11262.8 KFP11048.1 - 0.0011 18.3 5.9 0.0011 18.3 5.9 2.0 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 TPR_8 PF13181.6 KFP11048.1 - 0.22 11.8 1.1 10 6.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CHD5 PF04420.14 KFP11048.1 - 0.37 10.6 4.6 1.3 8.8 4.6 1.9 1 1 0 1 1 1 0 CHD5-like protein DUF5094 PF17015.5 KFP11048.1 - 0.43 10.7 16.6 1.2 9.2 3.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5094) NYD-SP28_assoc PF14775.6 KFP11048.1 - 0.55 10.4 15.2 0.98 9.6 1.9 3.6 3 1 0 3 3 3 0 Sperm tail C-terminal domain CotJB PF12652.7 KFP11048.1 - 0.68 10.2 3.4 4.2 7.7 0.1 2.8 3 0 0 3 3 3 0 CotJB protein DUF3829 PF12889.7 KFP11048.1 - 0.83 9.1 12.9 0.067 12.7 1.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) BST2 PF16716.5 KFP11048.1 - 1 10.0 19.8 2.9 8.5 2.4 3.7 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 bZIP_1 PF00170.21 KFP11048.1 - 1.7 8.8 21.5 1.9 8.7 0.6 4.4 2 2 1 4 4 4 0 bZIP transcription factor DUF775 PF05603.12 KFP11048.1 - 2.3 7.7 6.4 3.4 7.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF775) Mto2_bdg PF12808.7 KFP11048.1 - 2.8 8.3 16.0 2.1 8.7 0.6 3.4 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DASH_Dam1 PF08653.10 KFP11048.1 - 3.9 7.4 5.0 1.5 8.7 0.2 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 FIN1 PF17300.2 KFP11048.1 - 4.9 6.6 14.8 0.18 11.3 8.8 1.6 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 Wtap PF17098.5 KFP11048.1 - 4.9 7.1 22.3 3.9 7.4 12.1 3.4 2 2 0 2 2 2 0 WTAP/Mum2p family Mgr1 PF08602.10 KFP11048.1 - 4.9 5.9 10.2 3.2 6.5 7.6 1.9 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Sec20 PF03908.13 KFP11048.1 - 5.6 6.9 13.7 8.6 6.4 0.3 3.4 1 1 3 4 4 4 0 Sec20 UPF0242 PF06785.11 KFP11048.1 - 7.5 6.6 29.7 2.8 8.0 15.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFP11048.1 - 9.2 4.7 13.3 8.8 4.7 11.9 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family GAS PF13851.6 KFP11048.1 - 9.7 5.5 30.6 3.3 7.0 2.3 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4203 PF13886.6 KFP11049.1 - 2.3e-40 138.4 36.6 3.2e-40 138.0 36.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Med21 PF11221.8 KFP11050.1 - 2.7e-18 66.6 1.3 6.6e-18 65.4 1.3 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.11 KFP11050.1 - 0.0006 19.0 0.3 0.00071 18.7 0.3 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) F420_ligase PF01996.16 KFP11050.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 F420-0:Gamma-glutamyl ligase DUF2730 PF10805.8 KFP11050.1 - 0.073 13.2 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Pkinase PF00069.25 KFP11051.1 - 7.9e-61 205.7 0.1 3.3e-60 203.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11051.1 - 2.3e-27 95.9 2.0 7.2e-19 68.1 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFP11051.1 - 7.1e-08 33.0 1.6 1.3e-07 32.2 0.9 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 KFP11051.1 - 0.00096 18.6 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP11051.1 - 0.0011 18.0 0.1 0.0016 17.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP11051.1 - 0.0015 18.5 0.7 0.24 11.3 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP11051.1 - 0.0025 17.2 0.4 0.08 12.2 0.0 2.5 2 1 0 2 2 2 1 Kinase-like SAM_1 PF00536.30 KFP11053.1 - 5.7e-39 132.4 9.8 3.7e-17 62.5 0.7 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP11053.1 - 1.7e-33 114.6 8.2 2.4e-14 53.2 0.0 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) DUF16 PF01519.16 KFP11053.1 - 0.00054 20.4 12.7 0.00061 20.2 1.5 2.8 2 0 0 2 2 2 1 Protein of unknown function DUF16 SAM_PNT PF02198.16 KFP11053.1 - 0.0091 15.9 5.6 0.45 10.5 0.9 3.5 3 1 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain DUF4407 PF14362.6 KFP11053.1 - 0.092 12.1 11.7 0.046 13.1 4.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LRS4 PF10422.9 KFP11053.1 - 0.11 12.1 14.3 0.23 11.0 9.7 2.7 3 0 0 3 3 3 0 Monopolin complex subunit LRS4 DUF1640 PF07798.11 KFP11053.1 - 0.18 11.9 16.7 0.42 10.7 16.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) HMMR_N PF15905.5 KFP11053.1 - 0.43 10.0 24.5 0.9 8.9 24.5 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KFP11053.1 - 4.7 7.3 22.0 8.3 6.5 7.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 KFP11053.1 - 5.2 7.1 25.2 1.5 8.9 11.0 3.2 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain ADIP PF11559.8 KFP11053.1 - 6 6.9 23.8 9.3 6.3 9.8 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Rab15_effector PF15208.6 KFP11054.1 - 1.5e-122 407.5 0.3 1.6e-122 407.3 0.3 1.0 1 0 0 1 1 1 1 Rab15 effector FAD_binding_6 PF00970.24 KFP11055.1 - 1.4e-36 124.8 0.0 2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFP11055.1 - 1.2e-35 122.4 0.0 1.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFP11055.1 - 1.4e-05 25.2 0.0 0.00062 19.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain XendoU PF09412.10 KFP11056.1 - 1.1e-102 342.9 0.1 1.2e-102 342.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 KFP11056.1 - 0.0065 16.8 0.0 0.055 13.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial EndoU nuclease YqfQ PF14181.6 KFP11056.1 - 0.055 13.7 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Gb3_synth PF04572.12 KFP11057.1 - 1.9e-43 147.7 0.7 3.1e-43 147.1 0.7 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFP11057.1 - 2.4e-20 73.0 0.0 8e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFP11057.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.12 KFP11058.1 - 1.7e-43 147.9 0.7 2.7e-43 147.2 0.7 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFP11058.1 - 2.1e-20 73.2 0.0 7.1e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFP11058.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.12 KFP11059.1 - 2.3e-48 163.6 1.9 3.4e-48 163.1 1.9 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFP11059.1 - 6.2e-23 81.3 0.0 2.1e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFP11059.1 - 0.05 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain HEPN-like_int PF18867.1 KFP11059.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 HEPN-like integron domain ArfGap PF01412.18 KFP11060.1 - 3.1e-28 98.2 6.9 1.1e-27 96.5 1.2 2.7 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf FCH PF00611.23 KFP11061.1 - 9.7e-16 57.8 0.3 9.7e-16 57.8 0.3 3.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP11061.1 - 1.9e-15 56.2 0.1 4.1e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP11061.1 - 4.4e-15 55.3 0.2 4.4e-15 55.3 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP11061.1 - 2.8e-08 33.3 0.0 6.5e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain NPF PF16601.5 KFP11061.1 - 1.1e-05 26.0 8.3 1.1e-05 26.0 8.3 1.8 2 0 0 2 2 2 1 Rabosyn-5 repeating NPF sequence-motif SH3_10 PF17902.1 KFP11061.1 - 0.13 12.3 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 SH3 domain LIN52 PF10044.9 KFP11061.1 - 0.24 12.1 2.6 0.87 10.3 0.8 2.6 2 0 0 2 2 2 0 Retinal tissue protein DegS PF05384.11 KFP11061.1 - 6.8 6.2 18.3 0.083 12.4 8.0 2.7 3 1 0 3 3 3 0 Sensor protein DegS TTL PF03133.15 KFP11062.1 - 6.2e-114 380.1 0.7 8.3e-114 379.7 0.7 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFP11062.1 - 6.5e-08 32.1 0.0 0.00028 20.2 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFP11062.1 - 2.4e-05 23.7 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp bcl-2I13 PF12201.8 KFP11063.1 - 9.1e-07 28.9 0.0 1.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Bclx_interact PF08945.10 KFP11063.1 - 0.024 14.4 0.0 0.07 12.9 0.0 1.8 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain TspO_MBR PF03073.15 KFP11064.1 - 2.2e-49 167.0 13.2 2.5e-49 166.8 13.2 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1358 PF07096.11 KFP11064.1 - 3.1 7.8 5.8 0.55 10.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) TTL PF03133.15 KFP11065.1 - 2.8e-72 243.3 0.1 4e-72 242.8 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FXa_inhibition PF14670.6 KFP11066.1 - 3.3e-64 212.9 177.3 1.3e-12 47.7 9.1 12.1 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP11066.1 - 3.5e-45 151.5 86.7 2.1e-09 37.2 1.1 12.2 11 1 0 11 11 11 9 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 KFP11066.1 - 6.1e-35 118.7 35.3 4.2e-15 55.2 8.4 6.6 7 1 0 7 7 7 3 Putative ephrin-receptor like EGF_CA PF07645.15 KFP11066.1 - 1.8e-29 101.6 171.1 2.7e-09 37.1 8.5 11.9 12 0 0 12 12 12 7 Calcium-binding EGF domain EGF_3 PF12947.7 KFP11066.1 - 8.6e-22 77.1 141.0 2.7e-10 40.3 9.5 11.5 10 1 0 10 10 10 8 EGF domain CUB PF00431.20 KFP11066.1 - 4.3e-17 62.4 0.0 4.3e-17 62.4 0.0 2.5 3 0 0 3 3 3 1 CUB domain EGF PF00008.27 KFP11066.1 - 6.5e-16 58.3 137.0 9e-06 25.9 5.4 12.1 10 1 2 12 12 12 8 EGF-like domain hEGF PF12661.7 KFP11066.1 - 9.9e-05 22.8 12.6 0.00015 22.2 1.9 12.6 11 1 0 11 11 11 6 Human growth factor-like EGF DUF4375 PF14300.6 KFP11066.1 - 0.15 12.3 0.2 20 5.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) DUF5398 PF17376.2 KFP11066.1 - 0.17 12.5 0.5 0.47 11.1 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Metallophos PF00149.28 KFP11067.1 - 2.1e-11 44.7 0.6 3.2e-11 44.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP11067.1 - 2.1e-07 31.3 0.0 4.9e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfotransfer_1 PF00685.27 KFP11069.1 - 9.9e-50 169.5 0.2 1.4e-49 169.0 0.2 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11069.1 - 7.7e-09 36.2 0.1 1.1e-08 35.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_C92 PF05708.12 KFP11069.1 - 0.0067 16.5 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF758 PF05527.11 KFP11069.1 - 0.042 13.8 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Sulfotransfer_4 PF17784.1 KFP11069.1 - 0.055 13.3 0.2 0.15 11.9 0.2 1.5 1 1 0 1 1 1 0 Sulfotransferase domain NPA PF16469.5 KFP11069.1 - 0.063 13.9 0.1 0.16 12.6 0.1 1.6 1 1 0 1 1 1 0 Nematode polyprotein allergen ABA-1 FdsD PF11390.8 KFP11069.1 - 0.19 12.1 1.4 2.6 8.4 1.5 2.3 1 1 1 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Patatin PF01734.22 KFP11070.1 - 1.9e-06 28.2 0.0 3.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Bac_surface_Ag PF01103.23 KFP11071.1 - 1.1e-61 209.2 4.4 1.3e-61 208.9 4.4 1.0 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KFP11071.1 - 0.0029 18.1 0.0 0.0047 17.5 0.0 1.3 1 0 0 1 1 1 1 Surface antigen variable number repeat CH PF00307.31 KFP11072.1 - 3.1e-28 98.1 1.9 8.4e-18 64.5 1.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CH_2 PF06294.11 KFP11072.1 - 0.0016 18.5 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KFP11072.1 - 0.0016 18.2 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain ACT PF01842.25 KFP11072.1 - 0.1 12.4 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 ACT domain CH PF00307.31 KFP11073.1 - 4.5e-22 78.3 2.2 2.3e-14 53.5 1.8 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP11073.1 - 0.0012 18.6 0.1 0.55 10.1 0.1 2.5 2 1 0 2 2 2 2 CAMSAP CH domain DUF3130 PF11328.8 KFP11073.1 - 0.1 12.9 0.3 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Shisa PF13908.6 KFP11074.1 - 3.6e-07 30.6 5.7 3.6e-07 30.6 5.7 2.2 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator HbrB PF08539.11 KFP11077.1 - 7.4e-16 58.6 0.6 2.7e-14 53.5 0.1 2.3 1 1 1 2 2 2 2 HbrB-like CRAL_TRIO_2 PF13716.6 KFP11080.1 - 4.3e-38 130.6 3.5 7.7e-38 129.8 3.5 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KFP11080.1 - 5.9e-27 94.4 0.2 3.6e-18 65.9 0.0 2.7 2 1 1 3 3 3 2 RhoGAP domain CRAL_TRIO PF00650.20 KFP11080.1 - 9.7e-13 48.1 0.5 2e-12 47.1 0.5 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain YvbH_ext PF11724.8 KFP11080.1 - 1.1 9.7 4.8 2.3 8.6 0.4 2.5 1 1 1 2 2 2 0 YvbH-like oligomerisation region PHD PF00628.29 KFP11081.1 - 7e-08 32.2 6.8 1.5e-07 31.1 6.8 1.6 1 0 0 1 1 1 1 PHD-finger SH2_2 PF14633.6 KFP11081.1 - 0.079 12.4 0.4 0.18 11.2 0.4 1.5 1 0 0 1 1 1 0 SH2 domain Zf_RING PF16744.5 KFP11081.1 - 0.8 9.9 7.1 3.9 7.6 7.1 2.2 1 1 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KFP11081.1 - 2.7 8.3 9.4 6.7 7.1 9.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain NUP50 PF08911.11 KFP11082.1 - 5.9e-22 78.1 1.4 5.9e-22 78.1 1.4 3.6 4 1 1 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KFP11082.1 - 1.4e-10 41.5 0.0 2.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF2045 PF09741.9 KFP11083.1 - 1.1e-96 322.7 1.3 1.4e-96 322.4 1.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) RIB43A PF05914.12 KFP11085.1 - 2.2e-128 428.2 54.9 2.5e-128 428.0 54.9 1.0 1 0 0 1 1 1 1 RIB43A Herpes_UL35 PF04496.12 KFP11085.1 - 0.024 14.9 0.2 0.024 14.9 0.2 1.7 2 0 0 2 2 2 0 Herpesvirus UL35 family EGF_CA PF07645.15 KFP11086.1 - 1.8e-67 223.3 142.1 3.1e-11 43.3 5.1 10.7 11 1 0 11 11 11 9 Calcium-binding EGF domain cEGF PF12662.7 KFP11086.1 - 8.3e-58 191.9 66.5 2.5e-09 36.9 0.8 10.1 9 0 0 9 9 9 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP11086.1 - 1.2e-22 79.9 148.6 1.4e-06 28.5 8.5 11.5 12 0 0 12 12 12 7 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP11086.1 - 1e-11 44.8 117.4 0.00017 21.7 6.1 10.6 10 0 0 10 10 10 9 EGF domain ANATO PF01821.18 KFP11086.1 - 4.7e-05 24.2 19.7 0.00024 21.9 5.7 9.5 9 2 1 10 10 10 2 Anaphylotoxin-like domain EGF PF00008.27 KFP11086.1 - 0.00061 20.0 122.0 0.0052 17.0 8.3 11.4 10 0 0 10 10 10 7 EGF-like domain hEGF PF12661.7 KFP11086.1 - 0.011 16.3 6.7 0.011 16.3 6.7 12.6 12 1 0 12 12 12 0 Human growth factor-like EGF GBP_PSP PF02425.15 KFP11086.1 - 0.41 10.3 14.6 0.48 10.1 1.4 4.3 4 0 0 4 4 4 0 Paralytic/GBP/PSP peptide Atx10homo_assoc PF09759.9 KFP11087.1 - 8e-40 134.9 9.3 2.1e-38 130.3 0.7 3.9 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain wnt PF00110.19 KFP11090.1 - 9.4e-125 416.3 26.3 1.1e-124 416.1 26.3 1.0 1 0 0 1 1 1 1 wnt family zf-C4 PF00105.18 KFP11093.1 - 1.4e-28 99.2 15.9 2.6e-28 98.3 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP11093.1 - 5.4e-16 58.8 0.2 1.2e-15 57.7 0.2 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-BED PF02892.15 KFP11093.1 - 9.4 6.4 12.9 19 5.4 0.0 3.3 3 0 0 3 3 3 0 BED zinc finger C6_DPF PF10170.9 KFP11094.1 - 7.8e-41 138.4 3.5 9.5e-41 138.1 3.5 1.1 1 0 0 1 1 1 1 Cysteine-rich domain SpmSyn_N PF17950.1 KFP11096.1 - 2.3e-51 172.0 0.1 4e-51 171.2 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase N -terminal Spermine_synth PF01564.17 KFP11096.1 - 9.3e-45 152.3 0.1 1.4e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFP11096.1 - 3e-18 65.5 0.0 6e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Citrate_bind PF16114.5 KFP11096.1 - 0.055 13.0 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding Chisel PF15355.6 KFP11097.1 - 1.3e-40 137.5 2.7 1.4e-40 137.4 2.7 1.0 1 0 0 1 1 1 1 Stretch-responsive small skeletal muscle X protein, Chisel Kelch_1 PF01344.25 KFP11098.1 - 4.4e-37 125.4 0.4 6.1e-10 38.5 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP11098.1 - 1.8e-32 110.5 2.0 1.5e-08 34.6 0.0 6.3 2 2 4 6 6 6 4 Kelch motif BTB PF00651.31 KFP11098.1 - 2.2e-26 92.2 1.9 2.7e-26 92.0 1.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFP11098.1 - 3.9e-26 90.8 2.3 2.2e-08 33.9 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP11098.1 - 3.1e-17 62.4 0.6 0.028 14.7 0.0 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP11098.1 - 2e-15 56.1 2.6 2.2e-05 24.3 0.1 5.2 5 1 0 5 5 5 3 Kelch motif BACK PF07707.15 KFP11098.1 - 5.8e-11 42.4 0.1 1.4e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KFP11098.1 - 3.1e-09 36.6 3.9 0.01 15.8 0.0 5.8 6 0 0 6 6 6 2 Kelch motif DUF1170 PF06663.13 KFP11099.1 - 2e-62 210.7 12.2 5.1e-62 209.3 9.2 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFP11099.1 - 2.3e-39 133.4 0.5 7.9e-39 131.7 0.1 2.2 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFP11099.1 - 2e-15 56.9 1.8 7.3e-15 55.2 0.3 2.7 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFP11099.1 - 6.9e-15 55.4 5.7 1.5e-14 54.3 4.2 2.3 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 KFP11099.1 - 4.8e-10 39.4 0.7 3.2e-09 36.7 0.3 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KFP11099.1 - 5e-09 36.4 0.1 1.5e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP11099.1 - 3.7e-08 33.1 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 KFP11099.1 - 0.00058 20.2 2.3 0.15 12.4 2.9 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.6 KFP11099.1 - 0.002 18.4 0.2 0.033 14.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PH_13 PF16652.5 KFP11099.1 - 0.37 10.6 3.6 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Adaptin_binding PF10199.9 KFP11099.1 - 0.79 10.3 6.9 42 4.8 0.0 3.0 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 Opi1 PF08618.10 KFP11099.1 - 1.3 8.1 7.0 0.16 11.2 2.3 1.8 2 0 0 2 2 2 0 Transcription factor Opi1 PH_11 PF15413.6 KFP11099.1 - 2.5 8.5 19.3 0.11 13.0 10.6 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain ATG11 PF10377.9 KFP11099.1 - 4.4 7.4 8.4 0.077 13.1 0.7 2.0 2 0 0 2 2 1 0 Autophagy-related protein 11 eIF-1a PF01176.19 KFP11103.1 - 1.4e-21 76.0 0.1 1.8e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 MAP7 PF05672.11 KFP11105.1 - 1.9e-47 161.0 88.5 1.9e-47 161.0 88.5 3.3 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family THRAP3_BCLAF1 PF15440.6 KFP11106.1 - 2.8e-74 251.4 9.8 3.3e-74 251.1 9.8 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family PDCD7 PF16021.5 KFP11106.1 - 0.038 13.1 0.4 0.049 12.8 0.4 1.1 1 0 0 1 1 1 0 Programmed cell death protein 7 TMEM214 PF10151.9 KFP11106.1 - 0.043 12.3 0.0 0.37 9.2 0.1 1.9 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator SH3_9 PF14604.6 KFP11107.1 - 2.5e-54 180.9 2.9 4.2e-17 61.8 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFP11107.1 - 2.1e-43 145.7 7.7 3.8e-15 55.2 0.4 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFP11107.1 - 1.3e-42 143.2 4.0 3e-13 49.2 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.15 KFP11107.1 - 0.00025 20.8 0.0 1.8 8.2 0.0 3.2 2 1 0 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Tmemb_cc2 PF10267.9 KFP11107.1 - 0.0029 16.8 0.6 0.0045 16.2 0.6 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein TrkA_C PF02080.21 KFP11107.1 - 0.3 10.9 1.8 5.2 7.0 0.1 3.0 3 0 0 3 3 3 0 TrkA-C domain COG2 PF06148.11 KFP11107.1 - 0.35 10.9 3.4 0.7 10.0 3.4 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4071 PF13281.6 KFP11110.1 - 9.6e-166 551.4 1.3 9.6e-166 551.4 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 KFP11110.1 - 4.4e-65 219.7 0.0 9e-65 218.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11110.1 - 2.7e-42 144.8 0.0 5.3e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP11110.1 - 0.0016 17.9 0.0 0.0048 16.2 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP11110.1 - 0.004 16.0 0.0 0.0077 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TPD52 PF04201.15 KFP11110.1 - 0.8 9.3 6.8 0.43 10.2 1.2 2.9 3 0 0 3 3 3 0 Tumour protein D52 family RICH PF05062.12 KFP11110.1 - 7.1 7.1 11.2 5.5 7.4 2.0 3.2 3 0 0 3 3 3 0 RICH domain E1_dh PF00676.20 KFP11111.1 - 8.9e-122 405.7 0.0 1.1e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFP11111.1 - 0.014 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase 7tm_2 PF00002.24 KFP11113.1 - 3.8e-56 190.1 24.4 6.6e-56 189.3 24.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP11113.1 - 1.3e-17 64.0 5.0 3.8e-17 62.5 5.0 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF1980 PF09323.10 KFP11113.1 - 3.3 7.6 5.4 0.81 9.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Glyco_hydro_15 PF00723.21 KFP11114.1 - 7.9e-182 605.0 0.0 9.4e-182 604.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 F5_F8_type_C PF00754.25 KFP11115.1 - 1.6e-30 105.9 0.7 1.6e-30 105.9 0.7 1.4 2 0 0 2 2 2 1 F5/8 type C domain KorB_C PF06613.11 KFP11115.1 - 0.00097 19.1 0.3 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 KorB C-terminal beta-barrel domain Pkinase PF00069.25 KFP11116.1 - 3.1e-74 249.7 0.0 4.9e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11116.1 - 2e-34 119.1 0.0 3.4e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP11116.1 - 9.3e-05 21.5 0.5 0.00021 20.4 0.5 1.6 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFP11116.1 - 0.0018 18.0 0.3 1.2 8.7 0.0 2.6 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFP11116.1 - 0.0058 16.2 0.8 0.012 15.2 0.8 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFP11116.1 - 0.4 9.4 0.0 0.4 9.4 0.0 2.7 3 0 0 3 3 3 0 Fungal protein kinase zf-C4 PF00105.18 KFP11118.1 - 4.2e-28 97.6 17.9 8.2e-28 96.7 17.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP11118.1 - 1e-16 61.1 4.1 1.9e-12 47.2 0.5 2.4 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor 7tm_2 PF00002.24 KFP11119.1 - 9.3e-48 162.7 23.6 1.5e-47 161.9 23.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.17 KFP11119.1 - 1.3e-25 90.2 0.0 2.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP11119.1 - 2.1e-11 44.2 0.1 3.5e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 KFP11119.1 - 2.3e-09 37.6 1.0 2.3e-09 37.6 1.0 2.8 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif GAIN PF16489.5 KFP11119.1 - 1.7e-05 24.3 0.4 4.4e-05 23.0 0.3 1.7 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Tex_N PF09371.10 KFP11119.1 - 0.00011 22.0 0.3 0.00024 20.8 0.0 1.7 2 0 0 2 2 2 1 Tex-like protein N-terminal domain Dicty_CAR PF05462.11 KFP11119.1 - 0.00017 20.8 10.4 0.00027 20.2 10.4 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Lectin_C PF00059.21 KFP11119.1 - 0.0096 16.6 0.2 0.32 11.8 0.0 2.9 3 0 0 3 3 3 1 Lectin C-type domain Laminin_G_2 PF02210.24 KFP11119.1 - 0.13 12.8 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Proteasome PF00227.26 KFP11120.1 - 4.9e-46 156.6 0.1 6.3e-46 156.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFP11120.1 - 9.5e-14 50.5 0.4 1.7e-13 49.7 0.4 1.4 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Pkinase PF00069.25 KFP11121.1 - 1.7e-64 217.8 0.0 2.1e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11121.1 - 2.1e-46 158.3 0.0 2.5e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP11121.1 - 2.4e-05 23.5 0.2 5e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP11121.1 - 0.0011 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP11121.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP11121.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RecG_N PF17190.4 KFP11121.1 - 0.045 14.5 0.3 0.25 12.1 0.2 2.2 3 0 0 3 3 3 0 RecG N-terminal helical domain PIP49_C PF12260.8 KFP11121.1 - 0.077 12.6 0.2 4.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Gln_deamidase_2 PF18626.1 KFP11121.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutaminase DENN PF02141.21 KFP11122.1 - 9e-47 159.4 2.8 9e-47 159.4 2.8 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KFP11122.1 - 7.3e-11 42.7 0.7 7.3e-11 42.7 0.7 2.6 3 0 0 3 3 3 1 uDENN domain dDENN PF03455.19 KFP11122.1 - 1.7e-10 40.7 2.0 3.9e-10 39.5 2.0 1.7 1 0 0 1 1 1 1 dDENN domain DZF PF07528.14 KFP11123.1 - 4.2e-79 265.7 0.0 6.6e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 KFP11123.1 - 4.2e-26 91.5 0.0 1.8e-13 51.0 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif SGP PF17228.2 KFP11123.1 - 0.0015 19.3 2.1 0.0015 19.3 2.1 1.9 2 0 0 2 2 2 1 Sulphur globule protein DND1_DSRM PF14709.7 KFP11123.1 - 0.2 11.9 8.3 4.1 7.7 0.1 3.8 4 2 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 JIP_LZII PF16471.5 KFP11123.1 - 0.32 11.2 2.2 0.38 11.0 0.3 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II RabGAP-TBC PF00566.18 KFP11124.1 - 2.7e-57 193.9 1.6 2.7e-57 193.9 1.6 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 KFP11124.1 - 3e-32 112.4 0.1 3e-32 112.4 0.1 2.8 3 1 0 3 3 3 1 Kinesin protein PID PF00640.23 KFP11124.1 - 8e-06 25.9 4.3 2e-05 24.6 0.0 3.1 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP11124.1 - 0.002 18.3 0.2 0.0073 16.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine-binding domain UPF0242 PF06785.11 KFP11124.1 - 0.0072 16.4 9.0 0.0072 16.4 9.0 3.4 1 1 2 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 KFP11124.1 - 0.1 12.4 54.7 0.02 14.7 48.6 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3452 PF11934.8 KFP11124.1 - 1.3 8.6 12.5 1.2 8.7 0.7 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) Lebercilin PF15619.6 KFP11124.1 - 3.6 7.2 45.9 4.9 6.8 36.3 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BTB PF00651.31 KFP11125.1 - 4.3e-18 65.6 0.1 1.4e-17 63.9 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP11125.1 - 5.2e-18 64.4 38.8 1.2e-05 25.5 2.6 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP11125.1 - 1.2e-16 60.3 19.0 3.7e-07 30.3 0.7 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP11125.1 - 1.7e-12 47.1 36.9 0.00017 22.2 2.7 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP11125.1 - 0.00019 21.1 21.4 0.0029 17.3 2.4 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-met PF12874.7 KFP11125.1 - 0.00026 21.3 22.6 0.015 15.6 1.8 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP11125.1 - 0.00036 20.2 23.9 0.0053 16.5 2.3 4.3 4 0 0 4 4 4 3 zinc-finger C2H2-type DUF899 PF05988.12 KFP11125.1 - 0.0011 18.5 0.1 0.0011 18.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF899) zf-C2H2_2 PF12756.7 KFP11125.1 - 0.0041 17.4 25.0 0.43 10.9 1.0 5.3 1 1 4 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 KFP11125.1 - 0.12 12.4 4.2 0.15 12.1 0.1 2.7 3 0 0 3 3 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 KFP11125.1 - 0.14 12.5 19.2 2.3 8.6 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KFP11125.1 - 0.4 10.6 3.4 9.1 6.3 0.0 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 KFP11125.1 - 0.42 10.4 8.3 27 4.7 0.1 4.2 1 1 3 4 4 4 0 GAGA factor AHH PF14412.6 KFP11125.1 - 0.58 10.2 7.0 88 3.2 7.0 2.8 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH zf-C2H2_6 PF13912.6 KFP11125.1 - 1.6 8.8 29.4 1.2 9.2 2.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Dof PF02701.15 KFP11125.1 - 2.2 8.5 8.0 0.094 12.9 0.8 2.4 1 1 1 2 2 2 0 Dof domain, zinc finger FYVE PF01363.21 KFP11125.1 - 3.4 7.9 21.3 23 5.2 14.7 3.4 1 1 1 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFP11125.1 - 4 7.6 9.0 29 4.9 2.3 3.8 2 1 0 3 3 3 0 Zinc ribbon domain BTB PF00651.31 KFP11126.1 - 6.2e-20 71.5 2.0 6.2e-20 71.5 2.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP11126.1 - 2.6e-14 52.9 22.8 5e-08 33.0 0.1 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP11126.1 - 4.6e-14 52.0 34.4 2.2e-05 24.7 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11126.1 - 5.8e-11 42.3 32.6 0.001 19.7 0.6 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFP11126.1 - 3.9e-07 30.2 18.2 0.0027 18.1 0.6 3.9 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Chordopox_E11 PF06138.12 KFP11126.1 - 0.004 17.5 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 Chordopoxvirus E11 protein zf-C2H2_11 PF16622.5 KFP11126.1 - 0.016 15.0 18.4 0.024 14.4 0.5 4.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP11126.1 - 0.058 13.7 20.8 0.33 11.3 8.2 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFP11126.1 - 0.12 12.7 23.4 1.4 9.3 4.7 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFP11126.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.3 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger Sprouty PF05210.13 KFP11126.1 - 0.2 12.0 7.1 0.065 13.6 3.3 2.1 2 0 0 2 2 2 0 Sprouty protein (Spry) zf-C2H2_8 PF15909.5 KFP11126.1 - 0.27 11.6 16.6 0.58 10.5 3.2 3.8 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-UBP PF02148.19 KFP11126.1 - 0.35 11.2 10.1 3.4 8.0 10.1 2.5 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_3rep PF18868.1 KFP11126.1 - 0.36 11.5 10.1 2.5 8.8 2.6 3.1 2 2 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KFP11126.1 - 0.39 10.5 27.2 0.63 9.9 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain ROS_MUCR PF05443.11 KFP11126.1 - 1 9.4 4.7 1.5 8.9 0.3 2.6 1 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-MYST PF17772.1 KFP11126.1 - 5.4 6.7 9.7 6.8 6.4 0.4 3.6 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2HE PF16278.5 KFP11126.1 - 8.1 7.0 23.9 11 6.6 5.1 3.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger ROQ_II PF18386.1 KFP11127.1 - 1.4e-33 114.5 1.5 4.2e-33 112.9 0.6 2.1 2 0 0 2 2 2 1 Roquin II domain zf-CCCH PF00642.24 KFP11127.1 - 2e-06 27.6 1.9 2e-06 27.6 1.9 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 KFP11127.1 - 1.1e-05 25.3 7.5 1.1e-05 25.3 7.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP11127.1 - 1.2e-05 25.5 7.4 1.2e-05 25.5 7.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP11127.1 - 1.5e-05 24.8 7.8 3.7e-05 23.6 7.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP11127.1 - 9e-05 22.3 4.5 9e-05 22.3 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP11127.1 - 0.00023 20.9 11.5 0.0049 16.7 8.0 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP11127.1 - 0.002 18.2 6.6 0.002 18.2 6.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 KFP11127.1 - 0.002 18.1 1.4 0.0049 16.9 1.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFP11127.1 - 0.0025 17.6 1.0 0.0047 16.7 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 KFP11127.1 - 0.0027 17.6 8.4 0.007 16.2 8.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Xin PF08043.12 KFP11127.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Xin repeat zf-C3HC4_2 PF13923.6 KFP11127.1 - 0.0084 15.9 7.8 0.026 14.4 7.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFP11127.1 - 0.79 9.9 8.0 0.29 11.3 5.0 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFP11127.1 - 1.3 8.8 5.6 2.8 7.8 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 KFP11127.1 - 1.8 8.5 5.0 4.2 7.3 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phosducin PF02114.16 KFP11128.1 - 9.1e-32 110.0 3.1 9.7e-32 109.9 3.1 1.0 1 0 0 1 1 1 1 Phosducin An_peroxidase PF03098.15 KFP11129.1 - 7.8e-39 133.6 0.0 1.3e-30 106.6 0.0 2.9 2 1 0 2 2 2 2 Animal haem peroxidase EGF PF00008.27 KFP11129.1 - 0.00013 22.2 12.4 0.00034 20.9 12.4 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP11129.1 - 0.15 12.7 5.4 0.37 11.5 5.4 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF RRF PF01765.19 KFP11130.1 - 5.8e-44 149.9 6.2 8.5e-44 149.4 6.2 1.3 1 0 0 1 1 1 1 Ribosome recycling factor DUF2072 PF09845.9 KFP11130.1 - 0.028 14.7 1.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF951 PF06107.11 KFP11130.1 - 0.05 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DUF3810 PF12725.7 KFP11130.1 - 0.64 9.3 5.7 0.2 10.9 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF883 PF05957.13 KFP11130.1 - 2.7 8.6 9.6 0.84 10.3 4.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KFP11130.1 - 3.2 8.3 9.7 3.5 8.2 5.7 2.4 2 1 0 2 2 2 0 YtxH-like protein TRIQK PF15168.6 KFP11130.1 - 4.1 7.4 5.6 0.83 9.6 1.5 1.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family RRM_1 PF00076.22 KFP11131.1 - 5.2e-12 45.4 0.1 8.2e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFP11131.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Y_Y_Y PF07495.13 KFP11132.1 - 0.061 13.3 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Y_Y_Y domain CHCH PF06747.13 KFP11133.1 - 1.3e-08 34.7 1.4 1.7e-08 34.4 1.4 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFP11133.1 - 0.036 14.1 1.9 0.11 12.5 2.0 1.7 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 KFP11133.1 - 0.054 13.7 1.7 0.075 13.3 1.7 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 KFP11133.1 - 0.06 13.4 0.7 0.081 12.9 0.7 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like TTL PF03133.15 KFP11136.1 - 1.5e-66 224.5 0.0 2.3e-66 223.9 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFP11136.1 - 1.9e-08 33.9 0.0 0.0001 21.6 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFP11136.1 - 5e-06 25.9 0.0 0.0082 15.4 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.11 KFP11136.1 - 0.0092 15.6 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFP11136.1 - 0.023 14.7 0.0 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Band_7 PF01145.25 KFP11137.1 - 2.5e-35 122.1 0.8 3e-35 121.8 0.8 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFP11137.1 - 0.00035 20.3 0.2 0.00054 19.7 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KFP11137.1 - 0.13 12.6 0.1 0.33 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage protein Gp68 Gelsolin PF00626.22 KFP11138.1 - 5.8e-105 343.3 0.2 1e-19 70.2 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat Lipoprotein_Ltp PF07553.11 KFP11138.1 - 0.0072 16.6 0.1 2.1 8.6 0.1 2.4 2 0 0 2 2 2 2 Host cell surface-exposed lipoprotein CutA1 PF03091.15 KFP11138.1 - 0.062 13.2 0.5 4.9 7.1 0.0 3.2 4 0 0 4 4 4 0 CutA1 divalent ion tolerance protein Ras PF00071.22 KFP11139.1 - 8.6e-61 204.3 0.1 9.9e-61 204.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11139.1 - 2.5e-32 111.6 0.0 3.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11139.1 - 1.7e-12 47.2 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP11139.1 - 2.8e-05 23.7 0.0 0.0013 18.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP11139.1 - 4.9e-05 23.4 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP11139.1 - 0.00031 20.7 0.1 0.64 9.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFP11139.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFP11139.1 - 0.0027 17.5 0.0 0.065 13.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KFP11139.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1863 PF08937.11 KFP11139.1 - 0.055 13.8 0.0 0.096 13.0 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Septin PF00735.18 KFP11139.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 KFP11139.1 - 0.11 12.9 0.0 0.47 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP11139.1 - 0.14 12.4 0.1 0.47 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain LRR_9 PF14580.6 KFP11140.1 - 1.1e-19 70.6 1.2 1.1e-19 70.6 1.2 4.1 3 1 1 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 KFP11140.1 - 1.1e-12 47.9 20.0 3.5e-06 27.3 0.3 6.0 2 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP11140.1 - 1.6e-11 43.8 19.5 1.2e-06 28.2 2.7 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KFP11140.1 - 2.9e-06 26.9 10.5 0.3 11.2 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 KFP11140.1 - 0.012 16.0 10.6 29 5.8 0.0 6.1 5 0 0 5 5 5 0 Leucine Rich Repeat DUF1380 PF07128.12 KFP11140.1 - 0.028 14.6 4.0 0.19 11.9 4.0 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) TRAF_BIRC3_bd PF16673.5 KFP11141.1 - 4.8e-21 74.3 3.0 1e-20 73.2 3.0 1.5 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain zf-TRAF PF02176.18 KFP11141.1 - 3.3e-07 30.9 6.9 3.3e-07 30.9 6.9 3.4 3 1 0 3 3 3 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFP11141.1 - 0.00061 19.6 10.8 0.00061 19.6 10.8 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP11141.1 - 0.0089 16.0 3.1 0.0089 16.0 3.1 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf_UBZ PF18439.1 KFP11141.1 - 0.021 14.4 8.6 0.064 12.9 0.6 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PhyH PF05721.13 KFP11141.1 - 0.17 12.1 0.2 3.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) DUF641 PF04859.12 KFP11141.1 - 0.54 10.6 4.2 2.9 8.3 1.0 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) zf-ACC PF17848.1 KFP11141.1 - 2.6 8.2 0.0 2.6 8.2 0.0 4.7 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain PHD PF00628.29 KFP11142.1 - 2.9e-15 55.9 17.7 5e-10 39.1 1.8 2.4 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 KFP11142.1 - 2.7e-14 52.6 0.2 6e-14 51.4 0.2 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PHD_2 PF13831.6 KFP11142.1 - 0.00017 21.1 3.4 0.00017 21.1 3.4 3.7 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 KFP11142.1 - 0.0012 18.8 1.7 0.0012 18.8 1.7 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 DUF4537 PF15057.6 KFP11142.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.22 KFP11142.1 - 0.0062 16.4 0.7 0.0062 16.4 0.7 3.8 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LBR_tudor PF09465.10 KFP11142.1 - 0.12 12.2 0.3 0.21 11.4 0.3 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain C1_2 PF03107.16 KFP11142.1 - 1.5 9.2 17.9 0.22 11.9 0.5 3.9 4 0 0 4 4 4 0 C1 domain Mtf2_C PF14061.6 KFP11143.1 - 2.9e-27 94.6 0.1 4.8e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Chromo PF00385.24 KFP11143.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CutA1 PF03091.15 KFP11144.1 - 4.6e-33 113.0 0.0 5.9e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Proteasom_PSMB PF10508.9 KFP11145.1 - 8.5e-180 598.5 0.0 9.5e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 KFP11145.1 - 6.4e-06 26.3 0.2 0.67 10.2 0.1 4.1 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 KFP11145.1 - 4.7e-05 23.7 0.0 0.069 13.5 0.0 4.1 4 2 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 KFP11145.1 - 0.00029 19.6 0.0 0.00084 18.0 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFP11145.1 - 0.002 18.2 0.1 3.6 7.6 0.1 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KFP11145.1 - 0.022 14.9 0.1 6.9 6.8 0.0 3.3 3 0 0 3 3 3 0 V-ATPase subunit H STAG PF08514.11 KFP11145.1 - 0.036 14.0 0.0 0.3 11.0 0.1 2.4 2 0 0 2 2 2 0 STAG domain Neurochondrin PF05536.11 KFP11145.1 - 0.071 11.5 0.5 1.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Neurochondrin RTTN_N PF14726.6 KFP11145.1 - 0.13 13.1 0.0 18 6.2 0.0 3.4 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Galactosyl_T PF01762.21 KFP11146.1 - 8.7e-39 133.4 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFP11146.1 - 2.3e-05 23.9 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fringe-like rve PF00665.26 KFP11148.1 - 1.9e-20 73.2 0.1 3.8e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP11148.1 - 5.9e-11 42.1 0.2 5.9e-11 42.1 0.2 2.3 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.24 KFP11148.1 - 1.8e-05 24.9 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.6 KFP11148.1 - 0.085 13.1 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 DDE domain rve_3 PF13683.6 KFP11148.1 - 0.1 12.4 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain zf-TFIIB PF13453.6 KFP11148.1 - 0.15 11.4 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Isochorismatase PF00857.20 KFP11149.1 - 3.9e-26 92.3 0.0 6.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family ADAM_spacer1 PF05986.14 KFP11151.1 - 9.9e-30 102.9 0.0 2.2e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP11151.1 - 7.9e-22 77.2 96.1 3.8e-08 33.4 12.4 7.3 7 2 0 7 7 6 5 Thrombospondin type 1 domain Pep_M12B_propep PF01562.19 KFP11151.1 - 4.3e-21 75.6 0.0 8.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KFP11151.1 - 3.5e-20 72.3 19.2 9.9e-20 70.8 9.5 5.9 6 1 1 7 7 4 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP11151.1 - 1.5e-19 70.7 1.8 1.5e-19 70.7 1.8 3.4 3 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFP11151.1 - 1.2e-12 48.4 0.6 3.4e-12 46.9 0.6 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP11151.1 - 3.8e-10 40.3 0.1 8.4e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP11151.1 - 1.7e-06 28.0 0.1 4.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP11151.1 - 1.8e-05 24.5 0.6 0.00015 21.5 0.6 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFP11151.1 - 0.00037 21.2 7.0 0.0032 18.2 7.0 2.9 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFP11151.1 - 0.0009 19.1 0.3 0.0016 18.3 0.3 1.3 1 0 0 1 1 1 1 Matrixin DUF3810 PF12725.7 KFP11151.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) UPF0258 PF06789.12 KFP11154.1 - 2.2e-45 154.5 1.0 2.4e-45 154.4 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) DUF3377 PF11857.8 KFP11154.1 - 0.011 15.6 0.4 0.017 15.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CHGN PF05679.16 KFP11156.1 - 3.1e-176 587.2 0.1 3.5e-176 587.0 0.1 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP11156.1 - 3.8e-10 39.3 0.1 9.2e-10 38.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP11156.1 - 2.4e-06 27.2 0.0 1.7e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFP11156.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 CLTH PF10607.9 KFP11159.1 - 6.3e-29 100.8 0.4 1.1e-28 100.0 0.4 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Mic1 PF07035.12 KFP11159.1 - 0.00061 19.5 1.3 0.0017 18.1 0.1 2.1 3 0 0 3 3 3 1 Colon cancer-associated protein Mic1-like zf-RING_UBOX PF13445.6 KFP11159.1 - 0.0042 17.1 0.4 0.33 11.0 0.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger TFIID_NTD2 PF04494.15 KFP11159.1 - 0.063 13.5 0.3 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain LisH PF08513.11 KFP11159.1 - 0.22 11.5 0.7 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 LisH 2-Hacid_dh_C PF02826.19 KFP11160.1 - 2.5e-57 193.1 0.0 3.6e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP11160.1 - 5.6e-29 100.5 0.0 6.9e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP11160.1 - 1.5e-05 25.3 0.0 3.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KFP11160.1 - 0.053 14.0 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Cellsynth_D PF03500.13 KFP11160.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Cellulose synthase subunit D F420_oxidored PF03807.17 KFP11160.1 - 0.13 12.9 0.0 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Spond_N PF06468.13 KFP11161.1 - 4.4e-77 258.6 0.5 5.9e-77 258.1 0.5 1.2 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.19 KFP11161.1 - 0.0096 16.1 3.5 0.018 15.2 3.5 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain EMP24_GP25L PF01105.24 KFP11162.1 - 7.7e-42 143.3 0.5 8.6e-42 143.1 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4665 PF15679.5 KFP11162.1 - 0.049 14.3 1.0 0.075 13.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) zf-RING_5 PF14634.6 KFP11163.1 - 2.9e-09 36.8 12.4 2.9e-09 36.8 12.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP11163.1 - 0.0028 17.5 14.8 0.022 14.6 14.6 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Flp_N PF03930.14 KFP11163.1 - 0.018 15.0 0.5 0.026 14.5 0.5 1.2 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus zf-C3HC4 PF00097.25 KFP11163.1 - 0.02 14.8 10.3 0.02 14.8 10.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP11163.1 - 0.051 13.6 12.0 0.23 11.5 11.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFP11163.1 - 0.075 13.4 12.4 0.25 11.7 12.4 2.0 1 0 0 1 1 1 0 Ring finger domain ADPrib_exo_Tox PF03496.14 KFP11163.1 - 0.087 12.2 0.5 0.28 10.5 0.5 1.8 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme zf-C3HC4_2 PF13923.6 KFP11163.1 - 0.36 10.7 13.8 4.4 7.2 13.8 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4653 PF15546.6 KFP11163.1 - 2.7 7.5 6.8 1.3 8.6 3.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4653) Rtf2 PF04641.12 KFP11163.1 - 3.5 6.9 9.4 6.3 6.1 9.4 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger I-set PF07679.16 KFP11165.1 - 5.3e-47 157.8 0.0 3.2e-17 62.4 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP11165.1 - 5e-41 139.2 0.1 2.8e-14 53.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP11165.1 - 1.2e-29 102.3 0.1 9.9e-11 41.7 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP11165.1 - 8.6e-27 93.3 0.0 4.2e-11 43.0 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP11165.1 - 3.3e-19 69.1 0.8 0.00015 21.9 0.1 5.2 3 2 0 4 4 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP11165.1 - 1.5e-10 40.4 0.1 0.041 13.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFP11165.1 - 4.5e-08 33.2 0.3 0.0075 16.5 0.1 3.7 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP11165.1 - 7.8e-07 29.4 0.0 0.062 13.7 0.0 3.5 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP11165.1 - 3e-05 24.0 0.2 0.0046 17.0 0.0 3.0 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP11165.1 - 5e-05 23.3 0.1 1.6 8.9 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFP11165.1 - 8.9e-05 22.6 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 G6B PF15096.6 KFP11165.1 - 0.024 14.4 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 G6B family zf-RRN7 PF11781.8 KFP11165.1 - 0.029 14.1 0.2 8.3 6.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 V-set_CD47 PF08204.11 KFP11165.1 - 0.15 12.0 0.2 2 8.4 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HLH PF00010.26 KFP11168.1 - 6.8e-06 25.9 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_29 PF00777.18 KFP11169.1 - 9.9e-77 258.0 0.0 1.2e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) RNA_pol_Rpb1_5 PF04998.17 KFP11170.1 - 5.5e-103 344.0 0.0 1.1e-102 343.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFP11170.1 - 6.5e-70 234.7 0.0 1.8e-69 233.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFP11170.1 - 1.1e-38 132.6 0.0 3.8e-38 130.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFP11170.1 - 1.5e-24 86.0 0.0 1e-23 83.3 0.0 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 KFP11170.1 - 9.7e-20 71.1 13.4 1.2e-16 61.0 2.2 4.4 4 0 0 4 4 4 3 RNA polymerase Rpb1, domain 1 Pox_C7_F8A PF03287.14 KFP11170.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus C7/F8A protein SDA1 PF05285.12 KFP11170.1 - 0.074 12.5 16.1 0.16 11.4 16.1 1.5 1 0 0 1 1 1 0 SDA1 RP-C_C PF11800.8 KFP11170.1 - 0.3 11.1 3.3 0.75 9.9 3.3 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region zf-RING_4 PF14570.6 KFP11170.1 - 0.39 10.5 3.9 1.5 8.6 3.9 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BUD22 PF09073.10 KFP11170.1 - 5.2 6.3 21.0 10 5.3 21.0 1.4 1 0 0 1 1 1 0 BUD22 PPR_2 PF13041.6 KFP11171.1 - 4.9e-19 68.3 5.3 1.2e-07 31.8 0.1 7.4 8 0 0 8 8 8 3 PPR repeat family PPR_3 PF13812.6 KFP11171.1 - 5.3e-12 45.6 0.0 7.6e-06 25.9 0.0 4.0 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFP11171.1 - 8.2e-07 28.6 0.1 0.00013 21.4 0.0 3.7 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFP11171.1 - 6.6e-05 22.5 0.0 13 5.6 0.0 5.6 7 0 0 7 7 7 2 PPR repeat PPR PF01535.20 KFP11171.1 - 0.00017 21.6 8.3 0.17 12.2 0.1 8.3 11 1 0 11 11 11 1 PPR repeat ECSIT PF06239.11 KFP11171.1 - 0.086 12.0 0.1 1.1 8.4 0.2 2.4 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Pep1_7 PF17232.2 KFP11171.1 - 3.9 8.0 8.0 0.13 12.7 1.1 2.2 2 0 0 2 2 2 0 Elicitor peptide 1-7 Mitofilin PF09731.9 KFP11172.1 - 2.7e-211 703.7 42.6 3.2e-211 703.5 42.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Clr5 PF14420.6 KFP11172.1 - 4.1 7.7 5.0 4 7.7 1.3 2.7 2 0 0 2 2 2 0 Clr5 domain Baculo_PEP_C PF04513.12 KFP11172.1 - 7.8 6.5 18.3 16 5.5 1.6 4.6 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L35p PF01632.19 KFP11173.1 - 1.1e-14 54.6 6.7 1.6e-14 54.2 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 IL33 PF15095.6 KFP11173.1 - 0.16 11.4 1.3 0.16 11.4 1.3 1.1 1 0 0 1 1 1 0 Interleukin 33 TB2_DP1_HVA22 PF03134.19 KFP11174.1 - 8e-27 93.0 10.9 1.1e-26 92.5 10.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFP11174.1 - 0.044 14.0 0.6 0.075 13.2 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) MHCassoc_trimer PF08831.10 KFP11174.1 - 0.069 13.2 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Snf7 PF03357.21 KFP11175.1 - 8.1e-42 142.7 17.7 8.1e-42 142.7 17.7 1.3 2 0 0 2 2 2 1 Snf7 zf-ZPR1 PF03367.13 KFP11175.1 - 0.021 14.7 0.9 0.021 14.7 0.9 1.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain AAA_6 PF12774.7 KFP11175.1 - 0.026 13.5 1.2 0.034 13.1 1.2 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Cauli_AT PF03233.13 KFP11175.1 - 0.95 9.4 6.0 0.16 11.9 0.5 2.1 1 1 0 2 2 2 0 Aphid transmission protein zf-RING_11 PF17123.5 KFP11176.1 - 2.5e-09 36.7 4.7 5.5e-09 35.6 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFP11176.1 - 5e-08 33.1 6.3 5e-08 33.1 6.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP11176.1 - 1.5e-06 28.0 5.9 3.3e-06 26.8 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP11176.1 - 8e-06 25.8 5.2 1.9e-05 24.6 5.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP11176.1 - 0.00075 19.3 4.7 0.002 18.0 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP11176.1 - 0.002 18.4 9.0 0.002 18.4 9.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP11176.1 - 0.0062 16.5 5.5 0.018 15.0 5.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP11176.1 - 0.076 12.9 8.8 0.16 11.8 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP11176.1 - 0.12 12.5 6.4 0.36 10.9 6.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP11176.1 - 1.6 8.4 13.1 3.7 7.3 13.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CLTH PF10607.9 KFP11177.1 - 3.6e-32 111.3 0.0 1e-31 109.8 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KFP11177.1 - 6.5e-06 26.1 0.2 1.5e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP11177.1 - 0.015 15.6 1.7 0.018 15.4 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 KFP11177.1 - 0.031 14.1 1.5 0.69 9.8 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SnoaL_4 PF13577.6 KFP11177.1 - 0.18 12.0 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-RING_5 PF14634.6 KFP11177.1 - 1.2 9.1 3.9 0.54 10.3 1.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain V-set PF07686.17 KFP11178.1 - 4e-20 72.0 0.4 5.1e-20 71.7 0.4 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP11178.1 - 2.3e-06 27.7 1.0 4.8e-06 26.7 1.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP11178.1 - 6.6e-06 26.6 0.3 1.4e-05 25.6 0.3 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP11178.1 - 8.5e-05 22.6 0.2 0.00015 21.8 0.2 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP11178.1 - 0.019 15.3 2.5 0.1 13.0 2.5 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFP11178.1 - 0.22 11.6 1.0 1.6 8.9 0.4 2.2 1 1 1 2 2 2 0 Izumo-like Immunoglobulin domain zf-met PF12874.7 KFP11180.1 - 9.7e-33 111.6 18.4 5.5e-09 36.1 0.3 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP11180.1 - 2.8e-16 59.3 13.5 0.00013 22.1 0.1 4.6 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFP11180.1 - 4.1e-07 29.6 14.0 0.036 13.8 0.2 4.4 4 0 0 4 4 4 3 U1 zinc finger zf-C2H2_2 PF12756.7 KFP11180.1 - 3.1e-05 24.2 13.2 0.013 15.9 0.1 4.2 1 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFP11180.1 - 0.01 16.6 18.0 0.11 13.4 0.0 4.9 5 0 0 5 5 4 0 C2H2-type zinc finger zinc-ribbon_6 PF10005.9 KFP11180.1 - 0.049 14.3 0.8 0.049 14.3 0.8 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 KFP11180.1 - 0.05 14.1 0.2 0.05 14.1 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type DZR PF12773.7 KFP11180.1 - 0.099 12.7 9.3 3.8 7.6 0.1 3.4 2 2 1 3 3 3 0 Double zinc ribbon zf-C2H2_9 PF16293.5 KFP11180.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.6 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 KFP11180.1 - 0.48 10.0 0.1 0.48 10.0 0.1 2.7 3 0 0 3 3 2 0 TFIIB zinc-binding zf-SCNM1 PF15803.5 KFP11180.1 - 0.94 9.2 8.6 22 4.8 0.3 4.3 4 1 0 4 4 4 0 Zinc-finger of sodium channel modifier 1 zf-DBF PF07535.12 KFP11180.1 - 1.3 9.2 9.7 53 4.0 0.5 4.2 4 0 0 4 4 4 0 DBF zinc finger SET PF00856.28 KFP11181.1 - 2.7e-13 50.7 0.0 4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFP11181.1 - 8.9e-10 38.5 17.7 8.9e-10 38.5 17.7 2.3 2 0 0 2 2 2 1 MYND finger DUF2315 PF10231.9 KFP11181.1 - 0.056 13.5 0.0 0.89 9.7 0.0 2.1 2 0 0 2 2 2 0 Apoptogenic protein 1 DAO PF01266.24 KFP11182.1 - 3.4e-44 151.9 0.0 6.3e-44 151.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFP11182.1 - 7.7e-42 142.1 0.1 1.5e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 KFP11182.1 - 1.1e-11 45.0 0.5 2.3e-11 44.0 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP11182.1 - 2e-10 39.5 0.7 0.00016 21.0 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP11182.1 - 1.7e-09 36.8 0.4 0.00018 21.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain FAD_binding_2 PF00890.24 KFP11182.1 - 6.8e-09 35.3 0.0 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KFP11182.1 - 5.5e-06 26.0 0.0 2.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KFP11182.1 - 7.9e-06 25.2 0.0 0.00072 18.7 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A EF-hand_5 PF13202.6 KFP11182.1 - 7.1e-05 22.1 1.5 0.098 12.2 0.1 2.6 2 0 0 2 2 2 2 EF hand Pyr_redox_2 PF07992.14 KFP11182.1 - 7.7e-05 22.1 0.6 0.0017 17.7 0.1 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 KFP11182.1 - 8e-05 22.4 0.0 0.00023 20.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 KFP11182.1 - 0.00093 19.5 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain NAD_binding_8 PF13450.6 KFP11182.1 - 0.0022 18.2 0.2 0.011 15.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFP11182.1 - 0.0036 16.1 0.0 0.0059 15.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFP11182.1 - 0.015 14.6 0.0 0.091 12.0 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFP11182.1 - 0.032 13.5 0.0 0.098 11.9 0.0 1.8 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KFP11182.1 - 0.095 13.3 1.0 0.31 11.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP11182.1 - 0.097 11.9 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Gly_acyl_tr_N PF06021.11 KFP11182.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Hormone_recep PF00104.30 KFP11183.1 - 2.1e-24 86.3 0.0 3.6e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor Glycos_transf_2 PF00535.26 KFP11184.1 - 4.6e-36 124.2 0.0 7.7e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP11184.1 - 3.3e-16 59.7 3.0 6.5e-15 55.5 3.2 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP11184.1 - 8.5e-08 32.4 0.0 1.6e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP11184.1 - 8.4e-06 25.4 0.1 1.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP11184.1 - 8.9e-06 25.4 0.0 2.6e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP11184.1 - 0.0034 18.1 0.0 3.3 8.5 0.0 2.6 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like BTB PF00651.31 KFP11185.1 - 5e-22 78.2 0.0 5.7e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain Tubulin PF00091.25 KFP11186.1 - 2.7e-59 200.7 0.0 4.2e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP11186.1 - 8.3e-43 145.6 0.1 1.3e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP11186.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFP11186.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin like 7tm_3 PF00003.22 KFP11187.1 - 3.1e-52 177.7 8.2 5.4e-52 176.9 8.2 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFP11187.1 - 6.7e-21 74.8 0.0 2.5e-15 56.5 0.0 2.5 1 1 1 3 3 3 2 Receptor family ligand binding region DUF3995 PF13160.6 KFP11187.1 - 0.02 15.2 0.5 0.02 15.2 0.5 3.1 2 1 1 4 4 4 0 Protein of unknown function (DUF3995) Kei1 PF08552.11 KFP11187.1 - 0.022 14.7 1.2 1.8 8.4 0.1 2.9 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 LRRC37AB_C PF14914.6 KFP11187.1 - 0.043 13.7 0.4 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain TctB PF07331.11 KFP11187.1 - 0.78 10.0 16.8 0.56 10.5 0.2 3.4 1 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF1700 PF08006.11 KFP11187.1 - 8.7 5.8 9.3 1.3 8.5 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) zf-C2H2 PF00096.26 KFP11188.1 - 2.2e-11 43.6 6.6 1.7e-05 25.0 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP11188.1 - 9.6e-10 38.4 11.6 2.6e-06 27.6 1.7 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP11188.1 - 3.8e-08 33.5 6.5 0.00039 21.0 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP11188.1 - 7.2e-05 22.5 4.3 0.0026 17.5 0.5 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP11188.1 - 0.00065 19.6 5.6 0.018 15.0 0.2 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger XPA_N PF01286.18 KFP11188.1 - 0.001 19.1 0.3 0.092 12.8 0.1 2.2 2 0 0 2 2 2 1 XPA protein N-terminal zf-LYAR PF08790.11 KFP11188.1 - 0.0013 18.6 6.4 0.081 12.8 1.8 2.8 2 1 0 2 2 2 2 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KFP11188.1 - 0.0016 18.5 4.9 0.22 11.7 3.9 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-UBP PF02148.19 KFP11188.1 - 0.0021 18.4 1.4 0.015 15.6 1.4 1.9 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-trcl PF13451.6 KFP11188.1 - 0.0021 17.9 1.6 0.35 10.8 0.2 2.1 2 0 0 2 2 2 2 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFP11188.1 - 0.0024 17.4 0.3 0.47 10.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP11188.1 - 0.0026 17.8 0.8 0.024 14.7 0.8 2.0 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP11188.1 - 0.0035 17.6 0.4 2.9 8.3 0.1 2.4 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFP11188.1 - 0.0049 17.1 0.3 0.0063 16.7 0.3 1.2 1 0 0 1 1 1 1 TFIIH C1-like domain zf-met PF12874.7 KFP11188.1 - 0.0093 16.3 2.0 1.2 9.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type ADK_lid PF05191.14 KFP11188.1 - 0.01 15.8 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid GATA PF00320.27 KFP11188.1 - 0.014 15.0 1.6 0.11 12.2 1.6 2.2 1 1 0 1 1 1 0 GATA zinc finger DUF2321 PF10083.9 KFP11188.1 - 0.018 14.6 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HE PF16278.5 KFP11188.1 - 0.021 15.2 3.0 0.95 10.0 0.7 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger YhfH PF14149.6 KFP11188.1 - 0.023 14.6 0.4 7 6.7 0.1 2.1 2 0 0 2 2 2 0 YhfH-like protein C1_1 PF00130.22 KFP11188.1 - 0.048 13.5 3.6 0.14 12.1 0.6 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.22 KFP11188.1 - 0.055 13.7 1.5 0.24 11.6 1.5 1.8 1 1 0 1 1 1 0 LIM domain TFIIS_C PF01096.18 KFP11188.1 - 0.057 13.3 2.4 3.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) CpXC PF14353.6 KFP11188.1 - 0.062 13.3 0.1 7.8 6.6 0.0 2.0 1 1 1 2 2 2 0 CpXC protein DUF2197 PF09963.9 KFP11188.1 - 0.15 12.4 1.3 0.21 11.9 1.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-AN1 PF01428.16 KFP11188.1 - 0.44 10.8 3.7 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-CCHC_5 PF14787.6 KFP11188.1 - 0.72 9.6 0.1 0.72 9.6 0.1 2.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-H2C2_2 PF13465.6 KFP11189.1 - 6.2e-90 292.0 85.0 1.7e-09 37.7 0.8 12.6 13 0 0 13 13 12 12 Zinc-finger double domain zf-C2H2 PF00096.26 KFP11189.1 - 1.2e-64 211.4 88.5 5.4e-07 29.7 1.9 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11189.1 - 4.7e-38 126.6 83.1 0.00046 20.8 2.1 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP11189.1 - 3.2e-19 68.8 44.7 0.00017 21.6 0.3 8.2 3 1 6 9 9 9 8 Zinc ribbon domain zf-LYAR PF08790.11 KFP11189.1 - 7.5e-12 44.9 49.6 0.097 12.6 0.5 11.8 12 0 0 12 12 12 5 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KFP11189.1 - 1.8e-11 44.0 38.4 0.23 11.8 0.0 11.5 12 1 1 13 13 13 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP11189.1 - 2.1e-11 43.2 44.4 0.14 11.7 0.1 12.0 12 0 0 12 12 12 3 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFP11189.1 - 5.8e-10 38.7 62.1 4.5e-05 23.1 0.8 11.7 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP11189.1 - 1.4e-08 34.5 74.9 0.0086 16.1 1.0 11.8 12 0 0 12 12 12 5 C2H2-type zinc finger FYDLN_acid PF09538.10 KFP11189.1 - 1.9e-08 34.9 23.9 1.9 9.2 2.2 10.9 1 1 10 11 11 11 1 Protein of unknown function (FYDLN_acid) XPA_N PF01286.18 KFP11189.1 - 9.7e-08 31.9 47.0 5.7 7.1 0.0 11.9 12 0 0 12 12 12 0 XPA protein N-terminal Zn_ribbon_SprT PF17283.2 KFP11189.1 - 2.4e-06 27.3 49.5 0.0077 16.1 2.5 9.3 8 2 0 8 8 7 2 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFP11189.1 - 3.6e-06 27.6 33.7 0.41 11.4 0.1 6.3 2 2 3 6 6 6 3 zinc-ribbon family HypA PF01155.19 KFP11189.1 - 5e-06 26.5 34.6 0.9 9.6 1.6 6.6 1 1 6 7 7 7 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3268 PF11672.8 KFP11189.1 - 6.2e-06 26.5 29.2 0.22 11.9 0.2 6.6 4 2 3 7 7 7 2 zinc-finger-containing domain ADK_lid PF05191.14 KFP11189.1 - 4.8e-05 23.2 35.2 0.68 10.0 0.7 8.8 2 2 8 10 10 10 3 Adenylate kinase, active site lid CpXC PF14353.6 KFP11189.1 - 7.1e-05 22.8 43.4 0.78 9.8 0.3 11.2 4 3 4 10 10 10 1 CpXC protein C1_4 PF07975.12 KFP11189.1 - 8.5e-05 22.7 44.0 0.013 15.7 0.3 7.8 2 1 8 10 10 10 5 TFIIH C1-like domain zf-trcl PF13451.6 KFP11189.1 - 0.00035 20.4 46.3 10 6.1 0.1 11.5 11 1 0 11 11 11 0 Probable zinc-ribbon domain Chordopox_RPO7 PF05864.12 KFP11189.1 - 0.027 14.7 8.2 12 6.2 0.0 5.4 6 0 0 6 6 4 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DNA_RNApol_7kD PF03604.13 KFP11189.1 - 0.027 14.2 45.6 1.3 8.8 0.3 11.4 12 0 0 12 12 12 0 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.18 KFP11189.1 - 0.03 14.2 55.0 1.3 9.0 0.2 11.9 12 0 0 12 12 12 0 Transcription factor S-II (TFIIS) zf_C2H2_ZHX PF18387.1 KFP11189.1 - 0.04 13.6 50.1 1.4 8.6 0.3 10.4 1 1 9 11 11 11 0 Zinc-fingers and homeoboxes C2H2 finger domain YhfH PF14149.6 KFP11189.1 - 0.065 13.2 47.0 10 6.2 0.0 11.0 11 0 0 11 11 11 0 YhfH-like protein zf-AN1 PF01428.16 KFP11189.1 - 0.076 13.2 63.5 8.3 6.7 0.2 12.1 10 2 2 12 12 12 0 AN1-like Zinc finger FAM178 PF14816.6 KFP11189.1 - 0.076 12.0 1.2 9 5.2 0.0 3.7 3 2 1 4 4 4 0 Family of unknown function, FAM178 DNA_ligase_OB_2 PF14743.6 KFP11189.1 - 0.09 12.8 0.6 8.7 6.5 0.0 3.6 3 1 1 4 4 3 0 DNA ligase OB-like domain LIM PF00412.22 KFP11189.1 - 0.13 12.5 47.9 6.2 7.1 0.8 9.6 1 1 10 11 11 11 0 LIM domain zf-Di19 PF05605.12 KFP11189.1 - 0.37 11.1 47.9 3.3 8.1 4.9 8.2 2 2 5 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding C1-set PF07654.15 KFP11189.1 - 0.4 11.1 4.2 19 5.7 0.1 4.3 2 2 3 5 5 5 0 Immunoglobulin C1-set domain zinc_ribbon_9 PF14369.6 KFP11189.1 - 0.67 10.3 49.0 4.3 7.7 0.1 10.5 10 2 1 11 11 11 0 zinc-ribbon zf-met PF12874.7 KFP11189.1 - 0.8 10.2 0.1 0.8 10.2 0.1 10.6 12 0 0 12 12 11 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 KFP11189.1 - 1.3 9.0 45.0 15 5.6 0.0 10.7 8 4 1 9 9 9 0 zinc-ribbon domain DUF3797 PF12677.7 KFP11189.1 - 2.6 8.0 0.0 2.6 8.0 0.0 6.6 10 0 0 10 10 7 0 Domain of unknown function (DUF3797) Zn-C2H2_12 PF18112.1 KFP11189.1 - 9.7 6.8 24.2 16 6.0 0.3 6.7 8 0 0 8 8 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 KFP11190.1 - 6.4e-17 61.0 9.5 4.7e-08 33.1 2.9 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP11190.1 - 1.5e-14 53.6 12.6 2.1e-10 40.6 1.1 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP11190.1 - 3.7e-11 42.9 8.6 1.2e-05 25.7 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP11190.1 - 3.7e-09 36.6 0.4 0.00043 20.5 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP11190.1 - 2e-06 28.0 3.0 0.0028 18.0 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFP11190.1 - 5.5e-06 25.9 1.6 0.024 14.2 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP11190.1 - 1.1e-05 25.4 1.2 2.5e-05 24.3 1.3 1.6 1 1 0 1 1 1 1 Zinc ribbon domain XPA_N PF01286.18 KFP11190.1 - 5.1e-05 23.2 1.7 0.087 12.9 0.2 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-BED PF02892.15 KFP11190.1 - 0.0003 20.8 4.4 0.24 11.4 1.5 2.1 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.6 KFP11190.1 - 0.00048 20.1 11.5 0.1 12.7 3.5 2.5 2 2 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFP11190.1 - 0.0011 18.8 1.9 0.14 12.1 0.1 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DZR PF12773.7 KFP11190.1 - 0.0012 18.8 0.4 0.0016 18.4 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_4 PF07975.12 KFP11190.1 - 0.0014 18.8 0.9 0.0034 17.6 0.9 1.6 1 1 0 1 1 1 1 TFIIH C1-like domain ADK_lid PF05191.14 KFP11190.1 - 0.0046 16.9 0.4 0.19 11.7 0.6 2.2 1 1 1 2 2 2 2 Adenylate kinase, active site lid zf-C2H2_8 PF15909.5 KFP11190.1 - 0.0055 17.0 1.1 0.014 15.7 1.1 1.6 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KFP11190.1 - 0.0057 16.3 3.3 0.27 10.9 0.5 2.1 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain YhfH PF14149.6 KFP11190.1 - 0.0059 16.5 1.0 2 8.4 0.1 2.2 2 0 0 2 2 2 1 YhfH-like protein CpXC PF14353.6 KFP11190.1 - 0.0064 16.5 0.8 0.6 10.2 0.1 2.0 1 1 1 2 2 2 1 CpXC protein DNA_RNApol_7kD PF03604.13 KFP11190.1 - 0.0082 15.8 0.9 3 7.6 0.1 2.2 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit zf-Di19 PF05605.12 KFP11190.1 - 0.01 16.1 2.5 0.049 13.9 0.1 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TFIIS_C PF01096.18 KFP11190.1 - 0.011 15.6 2.6 1.5 8.8 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-HIT PF04438.16 KFP11190.1 - 0.011 15.6 4.2 0.19 11.6 0.5 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_11 PF16622.5 KFP11190.1 - 0.011 15.4 5.5 0.4 10.5 1.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Prok-RING_1 PF14446.6 KFP11190.1 - 0.012 15.5 0.3 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 KFP11190.1 - 0.014 14.9 1.3 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KFP11190.1 - 0.016 14.6 2.1 0.088 12.3 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Yippee-Mis18 PF03226.14 KFP11190.1 - 0.023 14.9 0.4 5.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-C2H2_12 PF18112.1 KFP11190.1 - 0.026 15.0 1.1 0.35 11.4 0.1 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_ZIC PF18366.1 KFP11190.1 - 0.029 14.5 0.7 5.4 7.2 0.1 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain Zn_ribbon_SprT PF17283.2 KFP11190.1 - 0.03 14.2 3.6 0.64 10.0 3.6 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DUF2072 PF09845.9 KFP11190.1 - 0.036 14.3 1.2 1.4 9.2 0.1 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF2256 PF10013.9 KFP11190.1 - 0.037 14.1 0.6 3 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.19 KFP11190.1 - 0.04 14.0 0.5 0.044 13.8 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 KFP11190.1 - 0.044 14.0 1.0 6.7 7.0 0.1 2.0 1 1 0 1 1 1 0 LIM domain FYDLN_acid PF09538.10 KFP11190.1 - 0.052 14.2 0.4 0.42 11.3 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.7 KFP11190.1 - 0.1 13.0 1.9 2.6 8.4 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 KFP11190.1 - 0.1 12.6 1.5 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.8 KFP11190.1 - 0.14 11.6 1.4 5.7 6.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) zf-AN1 PF01428.16 KFP11190.1 - 0.24 11.6 5.3 0.7 10.1 0.4 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.7 KFP11190.1 - 0.24 11.4 3.8 0.49 10.4 0.2 2.1 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 KFP11190.1 - 0.27 11.0 4.2 5.6 6.8 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Desulfoferrod_N PF06397.12 KFP11190.1 - 0.31 10.7 3.8 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_9 PF14369.6 KFP11190.1 - 0.59 10.4 2.8 7.5 6.9 2.8 2.1 1 1 0 1 1 1 0 zinc-ribbon zf-Mss51 PF13824.6 KFP11190.1 - 0.79 9.9 4.4 1.3 9.1 0.8 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2HE PF16278.5 KFP11190.1 - 1.5 9.3 4.6 8.4 6.9 0.5 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Gly-zipper_Omp PF13488.6 KFP11191.1 - 2.3 8.3 24.1 0.15 12.1 7.9 3.0 3 1 0 3 3 3 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KFP11191.1 - 2.3 8.0 22.1 0.53 10.1 6.3 2.9 3 0 0 3 3 3 0 YMGG-like Gly-zipper Se-cys_synth_N PF12390.8 KFP11191.1 - 3.4 8.0 10.9 0.58 10.4 0.6 3.8 3 1 0 3 3 3 0 Selenocysteine synthase N terminal zf-C2H2 PF00096.26 KFP11192.1 - 5.3e-13 48.6 8.1 4.2e-06 26.9 0.7 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11192.1 - 1.4e-08 34.8 5.5 0.00029 21.4 0.5 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP11192.1 - 1.5e-08 34.7 0.5 1.5e-08 34.7 0.5 2.4 3 0 0 3 3 2 1 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KFP11192.1 - 3.1e-05 24.0 0.1 4.7e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 KFP11192.1 - 0.00012 22.0 8.8 0.0006 19.7 0.2 2.3 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP11192.1 - 0.00077 19.2 4.6 0.25 11.1 0.2 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KFP11192.1 - 0.00093 18.7 0.5 0.17 11.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 KFP11192.1 - 0.0015 18.5 2.1 0.31 11.1 0.3 2.5 2 1 1 3 3 3 1 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.6 KFP11192.1 - 0.0022 17.9 2.7 0.0097 15.8 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2H2_jaz PF12171.8 KFP11192.1 - 0.0023 18.2 0.0 2.3 8.6 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFP11192.1 - 0.0033 17.3 0.5 1.1 9.2 0.1 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger DZR PF12773.7 KFP11192.1 - 0.0066 16.5 0.5 0.0081 16.2 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon CpXC PF14353.6 KFP11192.1 - 0.0075 16.3 0.1 0.2 11.7 0.1 2.0 1 1 1 2 2 2 1 CpXC protein zf-Mss51 PF13824.6 KFP11192.1 - 0.0086 16.1 1.8 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_5 PF13719.6 KFP11192.1 - 0.015 15.0 0.8 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFP11192.1 - 0.02 15.4 3.9 1.9 9.1 0.3 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF3268 PF11672.8 KFP11192.1 - 0.023 15.0 0.3 0.026 14.9 0.3 1.0 1 0 0 1 1 1 0 zinc-finger-containing domain HypA PF01155.19 KFP11192.1 - 0.043 13.8 0.4 0.05 13.6 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 KFP11192.1 - 0.052 13.8 0.2 0.057 13.7 0.2 1.1 1 0 0 1 1 1 0 TFIIH C1-like domain TF_Zn_Ribbon PF08271.12 KFP11192.1 - 0.072 12.6 2.1 0.3 10.6 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-AN1 PF01428.16 KFP11192.1 - 0.074 13.2 4.2 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger Zn_ribbon_SprT PF17283.2 KFP11192.1 - 0.079 12.9 0.8 0.079 12.9 0.8 2.4 2 1 0 2 2 2 0 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 KFP11192.1 - 0.12 13.1 0.6 1 10.1 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.6 KFP11192.1 - 0.13 12.2 3.3 2.7 8.0 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_2 PF13240.6 KFP11192.1 - 0.13 12.0 3.3 0.52 10.1 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 KFP11192.1 - 0.13 12.2 2.1 3.2 7.8 0.2 2.1 2 0 0 2 2 2 0 YhfH-like protein TFIIS_C PF01096.18 KFP11192.1 - 0.17 11.8 2.9 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_3 PF13878.6 KFP11192.1 - 0.25 11.2 2.1 8.3 6.3 0.4 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO DNA_RNApol_7kD PF03604.13 KFP11192.1 - 0.31 10.8 5.2 1.4 8.7 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2HC_2 PF13913.6 KFP11192.1 - 0.59 10.1 6.9 7.4 6.6 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rubredoxin_2 PF18073.1 KFP11192.1 - 0.88 9.4 5.4 5.9 6.7 0.4 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-HYPF PF07503.12 KFP11192.1 - 1.1 9.0 5.3 8.1 6.3 5.3 2.2 1 1 0 1 1 1 0 HypF finger zf-C2H2 PF00096.26 KFP11193.1 - 1.7e-07 31.3 12.4 0.00051 20.4 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP11193.1 - 7.8e-07 29.2 12.6 0.0053 17.1 0.2 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP11193.1 - 0.00041 20.9 11.4 0.075 13.9 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger XPA_N PF01286.18 KFP11193.1 - 0.0096 15.9 1.9 0.4 10.7 1.0 2.3 2 0 0 2 2 2 1 XPA protein N-terminal zf-LYAR PF08790.11 KFP11193.1 - 0.019 14.8 3.0 1.7 8.6 0.5 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFP11193.1 - 0.066 12.8 0.7 2 8.1 0.1 2.7 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFP11193.1 - 0.23 11.5 15.2 0.3 11.1 0.7 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KFP11193.1 - 0.77 10.2 10.6 5.9 7.4 2.7 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFP11194.1 - 3.9e-75 245.2 87.6 1.3e-08 34.8 2.4 13.1 13 0 0 13 13 13 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFP11194.1 - 3.1e-72 235.2 92.8 1.7e-08 34.5 2.2 12.1 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11194.1 - 7.9e-38 125.8 82.2 0.00066 20.3 5.4 12.1 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP11194.1 - 1.7e-19 69.2 61.8 0.0027 17.4 1.7 12.1 12 0 0 12 12 12 7 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFP11194.1 - 1.4e-14 53.9 61.8 0.00056 20.0 1.0 8.4 3 3 7 10 10 10 8 Zinc ribbon domain zf_UBZ PF18439.1 KFP11194.1 - 1.7e-13 49.9 55.3 0.49 10.0 0.1 12.1 12 0 0 12 12 12 8 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 KFP11194.1 - 4.8e-10 39.2 54.0 0.14 12.0 1.6 11.4 9 3 0 9 9 9 3 Probable zinc-ribbon domain zf-C2H2_6 PF13912.6 KFP11194.1 - 2.4e-09 37.0 89.8 0.007 16.3 0.4 12.6 12 1 0 12 12 12 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP11194.1 - 4.3e-09 36.4 38.8 0.76 10.1 0.0 11.0 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KFP11194.1 - 3.4e-08 33.3 42.2 0.0068 16.4 3.3 8.3 5 2 4 9 9 9 4 Adenylate kinase, active site lid zf-Di19 PF05605.12 KFP11194.1 - 6.7e-06 26.3 36.5 0.00099 19.4 1.8 6.0 6 1 0 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding DNA_RNApol_7kD PF03604.13 KFP11194.1 - 8.7e-06 25.3 55.0 0.41 10.4 0.1 11.9 12 0 0 12 12 12 4 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 KFP11194.1 - 0.00014 21.7 58.8 0.0062 16.4 2.2 10.3 9 1 1 10 10 10 3 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 KFP11194.1 - 0.00018 22.1 30.6 2.7 8.7 1.2 9.8 1 1 6 8 8 8 1 Protein of unknown function (FYDLN_acid) XPA_N PF01286.18 KFP11194.1 - 0.00029 20.8 58.0 10 6.3 0.2 12.0 12 0 0 12 12 12 0 XPA protein N-terminal zf-LYAR PF08790.11 KFP11194.1 - 0.00044 20.1 50.7 1.7 8.6 0.2 11.1 12 0 0 12 12 11 1 LYAR-type C2HC zinc finger DUF3268 PF11672.8 KFP11194.1 - 0.00055 20.3 39.8 0.011 16.0 1.3 6.1 2 2 3 7 7 7 3 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 KFP11194.1 - 0.00061 20.5 46.4 0.52 11.1 0.5 6.7 1 1 3 7 7 7 4 zinc-ribbon family C1_4 PF07975.12 KFP11194.1 - 0.00068 19.8 45.8 0.31 11.3 0.7 8.6 3 2 5 9 9 9 4 TFIIH C1-like domain HypA PF01155.19 KFP11194.1 - 0.0017 18.4 45.5 0.32 11.0 0.3 6.9 1 1 5 6 6 6 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HalOD2 PF18547.1 KFP11194.1 - 0.031 14.2 53.6 0.6 10.0 1.4 9.8 6 2 4 10 10 10 0 Halobacterial output domain 2 FAM209 PF15206.6 KFP11194.1 - 0.16 11.8 0.2 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 FAM209 family GAGA PF09237.11 KFP11194.1 - 0.84 9.5 23.0 5.8 6.8 0.0 6.2 4 2 2 6 6 6 0 GAGA factor CpXC PF14353.6 KFP11194.1 - 1.1 9.3 48.6 9.7 6.3 0.1 11.0 6 4 3 10 10 10 0 CpXC protein DUF3797 PF12677.7 KFP11194.1 - 1.1 9.1 0.0 1.1 9.1 0.0 7.6 8 4 1 10 10 7 0 Domain of unknown function (DUF3797) BolA PF01722.18 KFP11194.1 - 2.1 8.7 12.1 18 5.7 0.1 4.6 4 1 0 4 4 4 0 BolA-like protein zinc_ribbon_4 PF13717.6 KFP11194.1 - 2.7 8.0 53.8 6.2 6.8 1.0 10.5 8 4 2 10 10 10 0 zinc-ribbon domain zf-AN1 PF01428.16 KFP11194.1 - 3.3 8.0 70.4 7.6 6.8 0.1 12.1 10 1 2 12 12 12 0 AN1-like Zinc finger JAMP PF05571.12 KFP11196.1 - 1.5e-109 366.1 11.4 1.7e-109 366.0 11.4 1.0 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein GTPase_binding PF09027.10 KFP11196.1 - 0.083 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 GTPase binding COG2 PF06148.11 KFP11198.1 - 0.00095 19.3 6.8 0.001 19.1 1.8 2.1 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 KFP11198.1 - 0.0015 18.6 16.6 0.058 13.5 5.4 2.2 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KFP11198.1 - 0.0073 16.4 18.7 0.018 15.1 18.2 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein YtxH PF12732.7 KFP11198.1 - 0.032 14.8 3.9 5.3 7.6 1.6 2.4 2 1 0 2 2 2 0 YtxH-like protein Prefoldin_2 PF01920.20 KFP11198.1 - 0.055 13.4 13.3 0.35 10.9 1.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 KFP11198.1 - 0.076 12.3 9.4 0.097 12.0 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KfrA_N PF11740.8 KFP11198.1 - 0.21 12.3 12.3 1.1 10.0 4.1 2.6 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term GPHR_N PF12537.8 KFP11198.1 - 0.29 11.2 1.1 21 5.3 0.0 2.5 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Phage_GPO PF05929.11 KFP11198.1 - 0.5 9.9 10.0 0.07 12.7 3.2 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.9 KFP11198.1 - 0.53 9.3 15.1 2.9 6.9 15.1 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 KFP11198.1 - 0.77 10.0 11.7 1.5 9.1 11.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 KFP11198.1 - 1.1 8.7 7.5 1.4 8.4 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 KFP11198.1 - 1.5 9.3 16.6 0.68 10.4 4.3 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Gp-FAR-1 PF05823.12 KFP11198.1 - 1.7 9.0 9.3 4.4 7.7 3.0 2.5 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PEP-utilisers_N PF05524.13 KFP11198.1 - 1.7 8.8 11.6 2.9 8.1 2.2 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal FlgM PF04316.13 KFP11198.1 - 2 8.8 7.0 20 5.7 0.1 3.3 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM ZapB PF06005.12 KFP11198.1 - 2.1 8.8 17.5 4.2 7.9 6.4 2.8 1 1 1 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 KFP11198.1 - 2.5 8.2 13.5 4.2 7.4 13.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF883 PF05957.13 KFP11198.1 - 3 8.5 9.5 2.4 8.8 2.5 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MutS_III PF05192.18 KFP11198.1 - 3.3 7.9 7.0 3.9 7.7 7.0 1.1 1 0 0 1 1 1 0 MutS domain III HAUS6_N PF14661.6 KFP11198.1 - 5.4 6.5 12.0 13 5.2 11.4 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YabA PF06156.13 KFP11198.1 - 8.5 7.1 11.4 2.1 9.0 2.1 2.7 1 1 2 3 3 3 0 Initiation control protein YabA Reticulon PF02453.17 KFP11199.1 - 1.8e-46 158.0 7.5 2.6e-46 157.5 7.5 1.2 1 0 0 1 1 1 1 Reticulon DUF4736 PF15883.5 KFP11199.1 - 0.051 13.3 0.1 0.051 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Pecanex_C PF05041.15 KFP11202.1 - 1.1e-25 90.5 0.0 1.8e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) TSP_C PF05735.12 KFP11202.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Thrombospondin C-terminal region YoqO PF14037.6 KFP11202.1 - 4 8.0 8.9 17 6.0 0.2 3.4 3 0 0 3 3 3 0 YoqO-like protein adh_short PF00106.25 KFP11204.1 - 1.5e-48 164.9 0.0 1.8e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP11204.1 - 4.7e-29 101.6 0.0 5.8e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP11204.1 - 4.6e-09 36.4 0.0 7.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KR domain PP2C PF00481.21 KFP11206.1 - 5.2e-68 229.5 0.0 2.1e-61 207.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_C PF07830.13 KFP11206.1 - 1.1e-32 112.3 0.1 2.1e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain S6OS1 PF15676.5 KFP11208.1 - 8.2e-228 757.4 66.0 3.7e-226 752.0 66.0 2.0 1 1 0 1 1 1 1 Six6 opposite strand transcript 1 family T6PP_N PF18572.1 KFP11208.1 - 0.087 12.7 8.2 0.03 14.1 1.7 2.8 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF4825 PF16107.5 KFP11208.1 - 4.7 7.4 8.9 1.7 8.8 1.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4825) DUF3452 PF11934.8 KFP11208.1 - 6.2 6.4 9.1 14 5.2 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) SIX1_SD PF16878.5 KFP11209.1 - 8.6e-37 126.1 2.6 3.9e-36 124.0 0.6 2.0 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP11209.1 - 1.7e-13 50.2 3.4 4.2e-13 48.9 1.1 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP11209.1 - 9.1e-11 41.5 0.8 9.1e-11 41.5 0.8 1.7 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.22 KFP11209.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 KFP11209.1 - 0.035 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez CENP-B_N PF04218.13 KFP11209.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Thioredoxin_8 PF13905.6 KFP11210.1 - 7.6e-24 83.9 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KFP11210.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 KFP11210.1 - 0.00024 21.5 0.0 0.00048 20.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KFP11210.1 - 0.0014 18.5 0.2 0.031 14.1 0.0 2.4 2 1 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin PF00085.20 KFP11210.1 - 0.01 15.8 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin CpXC PF14353.6 KFP11210.1 - 0.03 14.4 0.0 0.083 12.9 0.0 1.8 1 1 0 1 1 1 0 CpXC protein AhpC-TSA PF00578.21 KFP11210.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family NCKAP5 PF15246.6 KFP11212.1 - 0.031 13.9 3.6 0.033 13.8 3.6 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein TPR_MLP1_2 PF07926.12 KFP11212.1 - 0.04 14.0 9.4 0.064 13.3 9.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KFP11212.1 - 0.27 9.1 5.3 0.28 9.1 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KFP11212.1 - 0.44 9.6 8.7 0.56 9.2 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rpr2 PF04032.16 KFP11213.1 - 0.044 14.1 0.2 0.063 13.6 0.2 1.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain 7tm_1 PF00001.21 KFP11214.1 - 6.5e-35 120.7 23.5 8e-35 120.4 23.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11214.1 - 2.6e-11 43.4 23.1 3.2e-11 43.1 23.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11214.1 - 0.0015 18.3 22.9 0.014 15.2 22.9 2.0 1 1 0 1 1 1 1 Olfactory receptor PBC PF03792.13 KFP11215.1 - 3.8e-65 219.2 0.3 7.4e-65 218.3 0.0 1.6 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFP11215.1 - 1.6e-18 66.3 0.5 3.2e-18 65.3 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP11215.1 - 3.9e-15 55.5 0.0 9.1e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 KFP11215.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec15 PF04091.12 KFP11215.1 - 0.029 13.8 0.3 0.046 13.1 0.3 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Eco57I PF07669.11 KFP11215.1 - 0.075 13.5 0.2 21 5.7 0.0 2.6 2 1 0 2 2 2 0 Eco57I restriction-modification methylase YdaS_antitoxin PF15943.5 KFP11215.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT NUC130_3NT PF08158.12 KFP11215.1 - 0.23 11.8 1.0 22 5.4 0.1 3.0 3 0 0 3 3 3 0 NUC130/3NT domain E1-E2_ATPase PF00122.20 KFP11216.1 - 0.023 14.2 0.1 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 E1-E2 ATPase CX9C PF16860.5 KFP11217.1 - 6.2e-21 74.1 3.6 5e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KFP11217.1 - 6.7e-06 26.1 7.1 0.00021 21.3 2.6 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 KFP11217.1 - 1.8e-05 24.7 7.0 0.28 11.3 0.3 3.0 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KFP11217.1 - 0.0003 20.5 0.7 0.0003 20.5 0.7 2.2 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 KFP11217.1 - 0.0024 18.2 4.3 0.14 12.6 1.1 2.2 1 1 1 2 2 2 2 GCK domain DUF1690 PF07956.11 KFP11217.1 - 0.041 14.3 0.3 0.044 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) COX17 PF05051.13 KFP11217.1 - 0.059 13.7 3.3 2.8 8.4 0.8 2.9 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KFP11217.1 - 0.062 13.6 6.6 0.55 10.6 4.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 KFP11217.1 - 0.088 13.1 4.2 1.1 9.6 0.6 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Homeodomain PF00046.29 KFP11218.1 - 2.7e-18 65.6 2.9 5.8e-18 64.5 2.8 1.7 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 KFP11218.1 - 1.4e-16 60.5 6.4 2.2e-16 59.8 6.4 1.3 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 KFP11218.1 - 8.9e-05 22.3 0.6 0.00029 20.7 0.2 2.2 2 0 0 2 2 2 1 Homeobox KN domain Med3 PF11593.8 KFP11218.1 - 0.07 12.3 2.3 0.097 11.9 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_pol_B_palm PF14792.6 KFP11219.1 - 2.1e-39 134.3 0.1 4.5e-39 133.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KFP11219.1 - 2.1e-22 78.7 0.0 4.1e-21 74.5 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFP11219.1 - 2.5e-17 62.8 0.0 5.7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.6 KFP11219.1 - 1.7e-08 34.9 0.1 1.7e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KFP11219.1 - 0.00021 21.5 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_3 PF12836.7 KFP11219.1 - 0.0028 17.9 0.3 0.18 12.1 0.0 3.7 4 1 0 4 4 4 1 Helix-hairpin-helix motif HHH_8 PF14716.6 KFP11219.1 - 0.0079 16.5 0.3 1.2 9.6 0.1 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KFP11219.1 - 0.0084 16.3 0.0 0.029 14.6 0.0 1.9 1 1 0 1 1 1 1 Pathogenicity locus HHH_2 PF12826.7 KFP11219.1 - 0.026 14.6 0.0 9.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif WSN PF02206.18 KFP11219.1 - 0.039 13.9 0.2 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function HHH PF00633.23 KFP11219.1 - 0.047 13.6 1.3 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3900 PF13039.6 KFP11219.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) Porin_3 PF01459.22 KFP11220.1 - 1.5e-74 250.9 8.9 1.7e-74 250.7 8.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin IKBKB_SDD PF18397.1 KFP11221.1 - 7.2e-133 442.1 16.6 1.2e-132 441.3 16.6 1.4 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 KFP11221.1 - 5.6e-40 137.4 0.0 1.3e-39 136.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11221.1 - 1.5e-26 93.2 0.0 4.1e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.8 KFP11221.1 - 4.3e-15 55.4 8.8 4.3e-15 55.4 8.8 2.7 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain Pkinase_fungal PF17667.1 KFP11221.1 - 1.6e-07 30.5 0.0 3.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP11221.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ubiquitin PF00240.23 KFP11221.1 - 0.00028 20.6 0.1 0.001 18.8 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family APH PF01636.23 KFP11221.1 - 0.0013 18.7 0.5 0.0063 16.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFP11221.1 - 0.0092 15.5 0.2 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL TBK1_ULD PF18396.1 KFP11221.1 - 0.041 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Trypsin PF00089.26 KFP11222.1 - 2.3e-68 230.3 0.0 3.7e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP11222.1 - 1.3e-44 150.4 25.0 2.3e-23 82.3 3.8 3.2 3 0 0 3 3 3 2 Kringle domain fn1 PF00039.18 KFP11222.1 - 1.8e-05 24.8 4.3 1.8e-05 24.8 4.3 2.7 2 0 0 2 2 2 1 Fibronectin type I domain Trypsin_2 PF13365.6 KFP11222.1 - 1.9e-05 25.6 0.0 3.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF PF00008.27 KFP11222.1 - 0.002 18.4 9.0 0.002 18.4 9.0 3.9 5 0 0 5 5 5 1 EGF-like domain DUF316 PF03761.15 KFP11222.1 - 0.012 15.2 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 KFP11222.1 - 0.035 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) hEGF PF12661.7 KFP11222.1 - 0.23 12.1 10.6 0.17 12.6 5.9 3.4 2 0 0 2 2 2 0 Human growth factor-like EGF Adap_comp_sub PF00928.21 KFP11223.1 - 4.6e-75 252.4 0.0 5.6e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP11223.1 - 4.1e-05 23.5 0.8 7.6e-05 22.7 0.8 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UPA_2 PF17809.1 KFP11224.1 - 1.9e-07 31.0 0.1 2.5e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 UPA domain Acyltransferase PF01553.21 KFP11225.1 - 3.2e-13 49.5 0.0 6.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Topo_C_assoc PF14370.6 KFP11225.1 - 0.12 12.3 0.1 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 C-terminal topoisomerase domain SLD5_C PF16922.5 KFP11226.1 - 4.7e-09 36.3 0.0 7.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KFP11226.1 - 7.6e-06 26.3 0.3 1.3e-05 25.7 0.2 1.6 1 1 0 1 1 1 1 GINS complex protein HipN PF18253.1 KFP11226.1 - 0.015 15.0 1.4 0.051 13.3 0.0 2.6 4 0 0 4 4 4 0 Hsp70-interacting protein N N-terminal domain Erf4 PF10256.9 KFP11227.1 - 5.3e-22 78.1 0.0 5.9e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TC1 PF15063.6 KFP11228.1 - 3.9e-36 122.7 0.4 4.9e-36 122.5 0.4 1.1 1 0 0 1 1 1 1 Thyroid cancer protein 1 MgtE_N PF03448.17 KFP11228.1 - 0.013 16.1 1.3 0.11 13.1 1.3 2.0 1 1 0 1 1 1 0 MgtE intracellular N domain HEAT_2 PF13646.6 KFP11228.1 - 0.05 14.0 0.2 2.5 8.5 0.2 2.0 1 1 1 2 2 2 0 HEAT repeats Toprim PF01751.22 KFP11228.1 - 0.055 13.7 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Toprim domain IDO PF01231.18 KFP11229.1 - 2.2e-95 320.0 0.0 2.4e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KFP11229.1 - 0.068 11.9 0.0 0.29 9.8 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1864) Reprolysin PF01421.19 KFP11230.1 - 2.6e-67 226.6 0.1 4.5e-67 225.8 0.1 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP11230.1 - 1.9e-35 121.8 5.6 1.9e-35 121.8 5.6 3.7 4 2 1 5 5 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP11230.1 - 6.1e-33 114.0 0.2 1.4e-32 112.9 0.2 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFP11230.1 - 6.3e-21 75.4 0.2 6.3e-21 75.4 0.2 1.9 2 0 0 2 2 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFP11230.1 - 4.6e-19 69.0 28.4 4.6e-19 69.0 28.4 4.9 4 1 1 5 5 4 1 Disintegrin Reprolysin_3 PF13582.6 KFP11230.1 - 5.1e-15 56.1 0.1 1e-14 55.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP11230.1 - 8.8e-12 45.1 0.1 1.4e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP11230.1 - 2.2e-09 37.5 0.5 4.5e-09 36.5 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFP11230.1 - 0.00017 21.8 12.4 0.00017 21.8 12.4 6.2 5 2 1 6 6 3 1 EGF-like domain Peptidase_M57 PF12388.8 KFP11230.1 - 0.008 15.8 1.7 0.014 15.0 1.7 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 KFP11230.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 KFP11230.1 - 0.1 11.5 0.3 0.18 10.7 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 KFP11230.1 - 1.4 8.8 6.5 0.13 12.1 0.2 2.3 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A PH PF00169.29 KFP11231.1 - 5.7e-13 49.3 2.6 2.8e-05 24.6 0.5 2.9 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 KFP11231.1 - 1.7e-07 31.4 2.8 0.0005 20.3 0.2 3.0 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP11231.1 - 6.2e-07 29.8 1.5 0.0012 19.3 0.6 2.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFP11231.1 - 0.0033 17.8 0.5 0.014 15.8 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KFP11231.1 - 0.0057 16.8 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology LETM1 PF07766.13 KFP11232.1 - 7.7e-101 336.9 6.5 9.1e-101 336.7 6.5 1.0 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 KFP11232.1 - 0.0063 16.2 1.9 0.028 14.2 0.4 2.7 2 1 1 3 3 3 1 SAP domain RNA_GG_bind PF10258.9 KFP11233.1 - 2.9e-33 113.8 2.7 4.5e-33 113.1 0.2 2.6 3 0 0 3 3 3 1 PHAX RNA-binding domain FoP_duplication PF13865.6 KFP11233.1 - 0.0027 18.2 6.0 0.0031 18.0 4.5 1.9 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RINGv PF12906.7 KFP11235.1 - 1.2e-15 57.3 9.8 3e-15 56.0 9.8 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFP11235.1 - 0.0017 18.6 9.7 0.0017 18.6 9.7 1.7 2 0 0 2 2 2 1 Ring finger domain Vpu PF00558.19 KFP11235.1 - 0.037 13.8 0.2 0.064 13.0 0.2 1.3 1 0 0 1 1 1 0 Vpu protein zf-C3HC4 PF00097.25 KFP11235.1 - 0.094 12.6 5.9 0.42 10.5 5.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KFP11235.1 - 0.14 12.1 1.8 0.26 11.2 1.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FANCL_C PF11793.8 KFP11235.1 - 5.4 7.3 9.4 1.1 9.5 4.5 2.4 2 1 0 3 3 3 0 FANCL C-terminal domain DUF836 PF05768.14 KFP11236.1 - 1.1e-14 54.6 0.3 1.3e-14 54.3 0.3 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KFP11236.1 - 0.00044 20.4 0.2 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFP11236.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP11236.1 - 0.01 16.0 0.4 0.04 14.1 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin-like Laminin_EGF PF00053.24 KFP11237.1 - 1.3e-44 150.1 328.1 0.00081 19.5 20.6 18.7 5 4 13 18 18 18 15 Laminin EGF domain hEGF PF12661.7 KFP11237.1 - 4.9e-27 93.6 264.0 6.6e-05 23.4 7.0 22.1 22 1 0 22 22 22 16 Human growth factor-like EGF EGF_2 PF07974.13 KFP11237.1 - 4.9e-10 39.6 386.7 0.00037 20.8 18.4 26.1 22 8 4 26 26 26 13 EGF-like domain EGF PF00008.27 KFP11237.1 - 0.00012 22.3 330.3 0.005 17.1 15.6 23.3 24 1 0 24 24 24 12 EGF-like domain Syndecan PF01034.20 KFP11237.1 - 0.02 14.8 1.2 0.039 13.9 1.2 1.4 1 0 0 1 1 1 0 Syndecan domain Baculo_11_kDa PF06143.11 KFP11237.1 - 0.042 13.4 0.8 0.072 12.7 0.8 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Glyoxalase PF00903.25 KFP11240.1 - 6.5e-26 91.0 0.0 7.5e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFP11240.1 - 9e-10 38.8 0.0 3.4e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFP11240.1 - 2e-06 28.5 0.0 2.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFP11240.1 - 0.0073 16.2 0.0 1.5 8.8 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFP11240.1 - 0.045 13.9 0.0 0.15 12.2 0.0 1.9 2 1 0 2 2 2 0 Glyoxalase-like domain BTB PF00651.31 KFP11241.1 - 9.8e-28 96.6 0.3 4.2e-26 91.4 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP11241.1 - 6.2e-24 84.1 0.4 1.5e-22 79.7 0.4 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 KFP11241.1 - 1.6e-22 80.0 0.1 1.1e-10 41.7 0.1 2.2 2 0 0 2 2 2 2 F5/8 type C domain DUF3342 PF11822.8 KFP11241.1 - 0.019 15.1 0.0 0.98 9.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf-AN1 PF01428.16 KFP11242.1 - 1.2e-08 34.9 8.0 2.8e-08 33.8 8.0 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Membr_traf_MHD PF10540.9 KFP11243.1 - 5.9e-55 185.5 3.5 1.6e-54 184.1 3.5 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFP11243.1 - 9.8e-42 141.4 1.2 2e-26 92.3 0.3 3.1 3 0 0 3 3 3 2 C2 domain DUF1041 PF06292.17 KFP11243.1 - 8.1e-25 87.3 1.0 1.8e-23 82.9 0.0 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 KFP11243.1 - 2.6e-11 43.2 6.1 7e-11 41.8 6.1 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Exo70 PF03081.15 KFP11243.1 - 0.0074 15.4 0.8 1.6 7.7 0.5 2.6 2 1 0 2 2 2 2 Exo70 exocyst complex subunit Ank_2 PF12796.7 KFP11244.1 - 3.3e-53 178.2 10.6 1.7e-15 57.3 0.0 6.1 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP11244.1 - 4e-48 161.2 7.1 1.1e-09 38.6 0.0 8.6 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP11244.1 - 2.6e-43 141.0 10.4 0.00011 22.3 0.0 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 KFP11244.1 - 2.5e-30 103.6 15.6 0.0028 18.0 0.0 10.9 9 2 2 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KFP11244.1 - 4.2e-29 100.2 15.0 4e-09 36.5 0.3 8.7 3 2 6 10 10 10 7 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP11244.1 - 1.6e-09 37.9 5.9 3.7e-09 36.8 5.9 1.6 1 0 0 1 1 1 1 SOCS box UIM PF02809.20 KFP11244.1 - 0.073 13.0 3.3 0.15 12.0 3.3 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif LAP1C PF05609.12 KFP11245.1 - 1.1e-92 311.6 0.7 1.2e-92 311.5 0.7 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Stap_Strp_tox_C PF02876.17 KFP11245.1 - 0.022 15.0 0.0 0.061 13.6 0.0 1.7 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain PRIMA1 PF16101.5 KFP11246.1 - 7.9e-42 142.1 20.1 9e-42 141.9 20.1 1.0 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KFP11246.1 - 5.5 7.0 9.9 5.9 6.9 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator UNC-79 PF14776.6 KFP11247.1 - 3.1e-06 26.2 0.1 6.5e-06 25.2 0.1 1.5 1 1 1 2 2 2 1 Cation-channel complex subunit UNC-79 B_solenoid_dext PF18841.1 KFP11248.1 - 3.2 8.1 11.3 40 4.6 0.9 3.6 2 2 0 2 2 2 0 Beta solenoid repeat from Dextranase PHD PF00628.29 KFP11249.1 - 0.00029 20.7 4.2 0.00029 20.7 4.2 3.6 3 1 0 3 3 3 1 PHD-finger TMEM251 PF15190.6 KFP11250.1 - 5.7e-70 233.2 2.5 6.5e-70 233.1 2.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 251 DUF4064 PF13273.6 KFP11250.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AA_permease PF00324.21 KFP11250.1 - 0.013 14.1 0.2 0.017 13.7 0.2 1.2 1 0 0 1 1 1 0 Amino acid permease TctB PF07331.11 KFP11250.1 - 0.092 13.0 2.2 0.62 10.3 2.6 1.8 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.6 KFP11250.1 - 0.1 12.2 3.2 1.2 8.7 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ins134_P3_kin PF05770.11 KFP11251.1 - 2.3e-83 278.7 0.1 3.3e-83 278.1 0.1 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 KFP11251.1 - 5.1e-19 68.5 1.5 2.5e-18 66.2 0.7 2.4 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain RimK PF08443.11 KFP11251.1 - 0.00028 20.6 0.1 0.58 9.7 0.0 2.6 3 0 0 3 3 3 2 RimK-like ATP-grasp domain Granin PF01271.17 KFP11252.1 - 3.5e-40 138.5 92.8 5.1e-20 71.9 54.7 3.1 1 1 2 3 3 3 2 Granin (chromogranin or secretogranin) Golgin_A5 PF09787.9 KFP11254.1 - 6.5e-139 462.6 29.1 6.5e-139 462.6 29.1 3.7 2 1 2 4 4 4 2 Golgin subfamily A member 5 Spc7 PF08317.11 KFP11254.1 - 5.3e-05 22.2 93.4 0.0048 15.8 12.6 5.0 2 1 3 5 5 5 4 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KFP11254.1 - 0.013 15.3 1.0 0.013 15.3 1.0 4.9 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HOOK PF05622.12 KFP11254.1 - 0.11 10.6 91.4 0.069 11.3 27.4 2.5 2 1 0 3 3 3 0 HOOK protein TPR_MLP1_2 PF07926.12 KFP11254.1 - 0.79 9.8 106.0 0.085 12.9 21.1 6.3 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein Peptidase_C13 PF01650.18 KFP11255.1 - 8.2e-117 389.2 2.2 1.4e-116 388.5 2.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family DUF2675 PF11247.8 KFP11255.1 - 0.1 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) VPS9 PF02204.18 KFP11256.1 - 5.8e-28 97.2 1.0 9.2e-28 96.5 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 KFP11256.1 - 8.8e-06 26.3 0.3 3.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.24 KFP11256.1 - 0.025 14.7 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 SH2 domain Lactamase_B_6 PF16661.5 KFP11258.1 - 1.8e-63 213.5 0.0 4.5e-63 212.2 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFP11258.1 - 5e-42 144.0 2.1 2.2e-41 141.9 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFP11258.1 - 1.6e-20 73.5 0.0 3.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFP11258.1 - 2.7e-15 56.0 0.0 5.8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFP11258.1 - 2.1e-06 27.9 0.0 4.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFP11258.1 - 8.8e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFP11258.1 - 0.0018 17.6 0.1 0.018 14.3 0.0 2.4 2 1 0 2 2 2 1 Putative beta-lactamase-like family NADH_oxidored PF08040.11 KFP11259.1 - 2e-36 123.4 0.1 2.2e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 MNLL subunit Josephin PF02099.17 KFP11260.1 - 5.9e-54 182.6 1.4 7.1e-54 182.3 0.0 1.8 2 0 0 2 2 2 1 Josephin SUIM_assoc PF16619.5 KFP11260.1 - 9e-19 67.3 7.4 2.3e-18 66.0 7.4 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 UIM PF02809.20 KFP11260.1 - 3.9e-11 42.1 27.3 5e-05 22.9 0.8 4.7 4 0 0 4 4 4 3 Ubiquitin interaction motif DUF4407 PF14362.6 KFP11261.1 - 0.0017 17.8 11.9 0.0017 17.8 11.9 11.8 3 3 7 10 10 10 2 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KFP11261.1 - 0.0023 18.0 1.1 0.0023 18.0 1.1 20.8 11 7 12 24 24 24 1 TolA binding protein trimerisation DMSP_lyase PF16867.5 KFP11261.1 - 9.7 5.8 11.3 16 5.1 0.3 5.2 3 0 0 3 3 3 0 Dimethlysulfonioproprionate lyase EGF_CA PF07645.15 KFP11262.1 - 1.9e-47 159.2 90.5 2.6e-11 43.5 8.3 7.5 8 1 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.7 KFP11262.1 - 7.3e-37 124.9 54.8 5.3e-12 45.4 3.8 7.9 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP11262.1 - 4.2e-25 87.7 95.9 2.8e-08 33.9 8.0 8.9 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP11262.1 - 5.1e-12 45.8 68.0 1.1e-06 28.7 4.2 7.9 7 1 1 8 8 8 5 EGF domain hEGF PF12661.7 KFP11262.1 - 1.4e-06 28.7 74.1 0.013 16.1 5.1 8.8 7 1 0 7 7 7 4 Human growth factor-like EGF EGF PF00008.27 KFP11262.1 - 0.0002 21.6 40.7 0.0016 18.7 8.2 8.0 8 0 0 8 8 8 4 EGF-like domain RANK_CRD_2 PF18278.1 KFP11262.1 - 1.6 8.9 23.1 2.9 8.1 0.2 6.2 6 0 0 6 6 6 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 C2 PF00168.30 KFP11263.1 - 2e-17 63.3 0.1 1.8e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMK-1 PF04802.15 KFP11264.1 - 4.8e-80 267.9 7.0 4.8e-80 267.9 7.0 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 KFP11264.1 - 0.0004 20.3 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 KFP11264.1 - 0.0069 16.6 0.0 0.025 14.9 0.0 2.0 1 0 0 1 1 1 1 RanBP1 domain Collagen PF01391.18 KFP11264.1 - 0.029 14.1 1.8 0.05 13.4 1.8 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MAGE_N PF12440.8 KFP11264.1 - 0.85 10.3 5.0 2.2 9.0 2.6 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF4392 PF14336.6 KFP11265.1 - 2.6e-117 391.5 0.0 3.5e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.12 KFP11265.1 - 1.3e-63 213.2 0.1 2.2e-63 212.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Pkinase PF00069.25 KFP11266.1 - 1.6e-141 470.3 0.4 3.6e-72 242.9 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11266.1 - 3.7e-67 226.3 0.1 2.1e-33 115.7 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KFP11266.1 - 4.9e-13 48.9 1.3 2.1e-09 37.1 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP11266.1 - 9.1e-13 48.7 3.3 0.00017 21.6 0.0 4.2 2 2 2 4 4 4 3 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP11266.1 - 1.8e-12 47.2 0.0 2.9e-05 23.5 0.0 3.0 2 2 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFP11266.1 - 2.6e-09 36.4 7.7 5e-06 25.5 0.2 3.1 3 0 0 3 3 3 2 Fungal protein kinase Haspin_kinase PF12330.8 KFP11266.1 - 5.6e-08 32.1 2.7 0.0041 16.1 0.5 2.4 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_C PF00433.24 KFP11266.1 - 8.9e-08 32.7 1.1 8.9e-08 32.7 1.1 2.1 2 0 0 2 2 1 1 Protein kinase C terminal domain RIO1 PF01163.22 KFP11266.1 - 6.2e-07 29.2 1.4 8.4e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 RIO1 family FTA2 PF13095.6 KFP11266.1 - 2e-06 27.6 1.3 1.2 8.7 0.0 3.6 3 1 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KFP11266.1 - 0.0019 17.8 2.2 0.014 14.9 0.0 2.9 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KFP11266.1 - 0.09 12.3 2.7 0.81 9.2 0.1 2.8 2 2 1 3 3 3 0 PhoP regulatory network protein YrbL SR-25 PF10500.9 KFP11266.1 - 0.092 12.3 7.0 0.2 11.3 7.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CaMBD PF02888.16 KFP11266.1 - 0.36 11.0 2.1 5.9 7.1 0.4 2.4 2 0 0 2 2 2 0 Calmodulin binding domain ANAPC3 PF12895.7 KFP11267.1 - 4.3e-12 46.1 11.2 1.6e-06 28.2 2.1 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP11267.1 - 2.3e-10 39.8 16.8 0.042 14.0 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP11267.1 - 1.3e-09 38.0 17.7 0.0012 19.5 0.1 7.6 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP11267.1 - 8.3e-08 32.6 12.2 0.0029 18.1 1.9 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP11267.1 - 2.5e-05 24.6 7.6 4.9 8.0 0.0 6.3 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP11267.1 - 2.5e-05 24.3 5.9 0.0025 17.9 0.1 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP11267.1 - 0.00016 22.3 10.1 4.2 8.1 0.0 5.4 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFP11267.1 - 0.0005 20.3 7.1 3.5 8.0 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP11267.1 - 0.001 19.3 8.5 0.36 11.3 0.3 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP11267.1 - 0.0011 18.2 4.8 0.17 11.1 1.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP11267.1 - 0.0028 17.8 13.5 0.0032 17.6 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP11267.1 - 0.0046 17.2 21.6 0.16 12.2 5.0 6.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP11267.1 - 0.0096 15.6 9.8 0.97 9.2 0.0 5.3 5 0 0 5 5 5 1 TPR repeat TPR_1 PF00515.28 KFP11267.1 - 0.019 14.8 21.6 6.6 6.7 0.3 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat ChAPs PF09295.10 KFP11267.1 - 0.14 11.1 0.3 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 KFP11267.1 - 0.18 11.4 1.3 0.71 9.5 0.1 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 KFP11267.1 - 0.25 11.3 9.0 0.31 11.0 0.6 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP11267.1 - 0.61 10.2 14.8 22 5.4 0.1 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Neur_chan_LBD PF02931.23 KFP11268.1 - 2.2e-49 167.9 2.8 3.4e-49 167.2 2.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP11268.1 - 3.2e-32 112.5 0.0 4.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.29 KFP11269.1 - 3.6e-49 167.6 0.0 5.9e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP11269.1 - 0.037 13.6 7.6 0.091 12.3 1.5 3.6 2 2 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF3322 PF11795.8 KFP11269.1 - 0.3 11.1 0.0 0.3 11.1 0.0 3.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) UBA_4 PF14555.6 KFP11269.1 - 0.98 9.3 3.1 0.57 10.0 0.4 2.1 2 0 0 2 2 2 0 UBA-like domain Ufd2P_core PF10408.9 KFP11270.1 - 3.5e-161 537.9 12.8 5.4e-161 537.3 12.8 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFP11270.1 - 2.1e-32 111.1 0.6 5.9e-32 109.7 0.6 1.8 1 0 0 1 1 1 1 U-box domain CK2S PF15011.6 KFP11270.1 - 3.3 7.6 8.1 9.3 6.1 1.1 3.8 4 0 0 4 4 4 0 Casein Kinase 2 substrate IFT46_B_C PF12317.8 KFP11272.1 - 1.4e-99 332.1 0.6 1.6e-99 331.9 0.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF1232 PF06803.12 KFP11272.1 - 0.44 10.4 3.3 0.84 9.5 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Adap_comp_sub PF00928.21 KFP11273.1 - 3.2e-35 121.8 0.4 4.5e-35 121.3 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP11273.1 - 5.8e-06 26.3 0.3 1e-05 25.5 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Dermcidin PF15291.6 KFP11273.1 - 0.1 13.2 0.2 0.18 12.3 0.2 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide MFS_1 PF07690.16 KFP11274.1 - 3.1e-38 131.6 34.4 5.1e-38 130.9 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5438 PF17506.2 KFP11274.1 - 0.17 12.2 0.8 29 5.1 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5438) Ribosomal_S25 PF03297.15 KFP11275.1 - 5.6e-42 142.0 0.3 6.4e-42 141.9 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TrmB PF01978.19 KFP11275.1 - 0.041 13.8 0.2 0.074 12.9 0.1 1.5 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 KFP11275.1 - 0.041 14.1 0.1 0.061 13.5 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RNA_pol_Rpc34 PF05158.12 KFP11275.1 - 0.046 13.1 0.0 0.05 13.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 KFP11275.1 - 0.055 13.4 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 KFP11275.1 - 0.06 12.9 0.5 0.11 12.1 0.2 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding CCDC84 PF14968.6 KFP11276.1 - 1.3e-45 156.6 4.9 1.5e-45 156.4 4.9 1.0 1 0 0 1 1 1 1 Coiled coil protein 84 7tm_4 PF13853.6 KFP11277.1 - 1.8e-48 165.7 13.1 2.1e-48 165.5 13.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11277.1 - 8.1e-29 100.8 14.6 1.3e-28 100.0 14.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11277.1 - 2.8e-05 23.6 11.6 4.2e-05 23.1 11.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Baculo_11_kDa PF06143.11 KFP11277.1 - 0.094 12.3 1.7 0.25 10.9 1.7 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3989 PF13150.6 KFP11277.1 - 0.16 11.8 0.4 0.3 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) TMEMspv1-c74-12 PF11044.8 KFP11277.1 - 1.3 9.0 2.7 3.3 7.8 2.7 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DED PF01335.21 KFP11278.1 - 0.00097 19.4 0.0 0.0036 17.6 0.0 2.0 2 0 0 2 2 2 1 Death effector domain Tim54 PF11711.8 KFP11279.1 - 0.034 12.9 2.1 0.045 12.5 2.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Lin-8 PF03353.15 KFP11279.1 - 0.27 10.8 8.4 0.34 10.4 8.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 KFP11279.1 - 1.5 8.2 19.9 1.9 7.8 19.9 1.1 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.12 KFP11279.1 - 1.7 6.8 9.8 2.3 6.4 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 KFP11279.1 - 2.1 6.5 15.1 2.6 6.2 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KFP11279.1 - 2.8 7.1 4.3 3.7 6.7 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KFP11279.1 - 3.8 6.2 8.8 4.8 5.8 8.8 1.1 1 0 0 1 1 1 0 Presenilin Pkinase_Tyr PF07714.17 KFP11280.1 - 3.3e-146 485.4 0.0 6.5e-86 287.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP11280.1 - 1.5e-74 250.7 0.0 2.5e-51 174.6 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain FERM_F2 PF18377.1 KFP11280.1 - 8.8e-44 148.6 0.1 2.2e-43 147.3 0.1 1.7 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain FERM_F1 PF18379.1 KFP11280.1 - 1.8e-39 133.7 0.6 1.8e-39 133.7 0.6 2.1 2 0 0 2 2 2 1 FERM F1 ubiquitin-like domain Jak1_Phl PF17887.1 KFP11280.1 - 3.3e-19 69.3 0.6 1.1e-18 67.6 0.2 2.0 1 1 1 2 2 2 1 Jak1 pleckstrin homology-like domain Kdo PF06293.14 KFP11280.1 - 3e-06 26.7 0.6 0.014 14.7 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP11280.1 - 8.8e-05 21.9 0.0 0.008 15.5 0.0 2.7 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFP11280.1 - 0.0017 18.0 1.3 0.23 11.0 0.1 2.5 2 0 0 2 2 2 2 RIO1 family FERM_M PF00373.18 KFP11280.1 - 0.0033 17.8 0.1 0.0085 16.5 0.1 1.8 1 0 0 1 1 1 1 FERM central domain APH PF01636.23 KFP11280.1 - 0.018 15.0 0.0 1 9.2 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RTC PF01137.21 KFP11281.1 - 1.8e-43 148.3 0.0 2.1e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFP11281.1 - 6.4e-36 123.0 0.0 1e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ank_2 PF12796.7 KFP11282.1 - 1e-41 141.4 12.8 3.2e-10 40.4 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP11282.1 - 3.5e-38 129.5 18.5 7e-10 39.2 0.1 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP11282.1 - 5.1e-38 128.6 11.7 3.3e-10 40.0 0.1 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP11282.1 - 6.8e-36 121.2 20.8 7.8e-08 32.4 0.7 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KFP11282.1 - 3.1e-31 103.9 8.3 1.4e-05 25.1 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat EccE PF11203.8 KFP11282.1 - 0.017 15.4 2.7 3.7 7.9 0.3 3.0 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Phasin PF05597.11 KFP11282.1 - 0.033 14.2 7.0 0.51 10.3 1.4 3.2 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5320 PF17253.2 KFP11282.1 - 0.27 12.3 1.7 0.89 10.7 1.7 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CLZ PF16526.5 KFP11282.1 - 5.9 7.3 13.6 2 8.8 2.5 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 KFP11282.1 - 6.8 7.1 11.3 2.5 8.5 2.6 2.8 2 0 0 2 2 2 0 Syntaxin-like protein Complex1_LYR PF05347.15 KFP11283.1 - 1e-18 67.1 1.0 1.2e-18 66.8 1.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP11283.1 - 2.2e-08 34.7 0.7 2.5e-08 34.5 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFP11283.1 - 0.0003 21.3 0.2 0.00034 21.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like AAA_5 PF07728.14 KFP11284.1 - 2.6e-122 403.2 0.0 6.7e-25 87.7 0.0 8.8 7 1 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFP11284.1 - 2.2e-64 214.3 3.7 2.4e-26 92.0 0.1 6.3 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KFP11284.1 - 3.9e-32 110.5 0.0 2.2e-31 108.1 0.0 2.5 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 KFP11284.1 - 8.9e-25 87.6 0.6 0.00094 19.6 0.1 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KFP11284.1 - 1.7e-23 82.9 0.0 2.1e-07 30.8 0.0 7.2 7 0 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFP11284.1 - 4.3e-22 78.5 2.6 0.00016 21.3 0.0 6.8 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 KFP11284.1 - 9.6e-22 78.2 26.6 0.001 19.5 0.0 10.3 10 2 0 11 11 9 6 AAA ATPase domain AAA_22 PF13401.6 KFP11284.1 - 3.6e-16 59.7 6.4 0.0038 17.5 0.0 8.5 8 0 0 8 8 6 4 AAA domain TsaE PF02367.17 KFP11284.1 - 3.9e-16 59.2 2.9 0.58 10.2 0.0 7.0 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynein_heavy PF03028.15 KFP11284.1 - 1.1e-15 57.8 0.0 0.0017 18.5 0.0 7.5 7 0 0 7 7 7 3 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 KFP11284.1 - 2.2e-15 57.4 10.7 0.14 12.8 0.0 9.5 10 0 0 10 10 7 4 AAA domain AAA_14 PF13173.6 KFP11284.1 - 4e-15 56.0 0.0 0.011 15.8 0.0 7.3 6 1 1 7 7 7 3 AAA domain Sigma54_activat PF00158.26 KFP11284.1 - 2.5e-14 53.3 0.4 0.8 9.4 0.0 7.1 7 0 0 7 7 7 4 Sigma-54 interaction domain ABC_tran PF00005.27 KFP11284.1 - 7.9e-14 52.3 7.5 0.02 15.4 0.0 8.1 7 0 0 7 7 6 2 ABC transporter Sigma54_activ_2 PF14532.6 KFP11284.1 - 3.7e-12 46.5 1.7 0.0033 17.5 0.0 7.0 7 0 0 7 7 6 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFP11284.1 - 6.9e-12 45.2 1.8 1.3 8.4 0.0 8.1 7 2 0 7 7 6 2 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 KFP11284.1 - 3e-11 42.9 0.9 0.2 10.6 0.0 6.4 6 0 0 6 6 6 2 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 KFP11284.1 - 1.5e-09 38.0 6.3 2 8.3 0.0 7.2 7 0 0 7 7 6 2 NACHT domain RsgA_GTPase PF03193.16 KFP11284.1 - 4e-09 36.6 4.9 3.2 7.7 0.0 6.8 6 0 0 6 6 6 1 RsgA GTPase Roc PF08477.13 KFP11284.1 - 8.2e-09 35.7 0.9 4.3 7.6 0.0 6.8 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KFP11284.1 - 1.9e-08 34.6 1.3 0.36 11.0 0.0 6.6 6 0 0 6 6 6 2 AAA domain DUF815 PF05673.13 KFP11284.1 - 2.4e-08 33.5 1.8 0.26 10.4 0.0 5.8 6 0 0 6 6 6 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KFP11284.1 - 3.6e-08 33.7 0.5 5.5 7.4 0.0 6.9 6 0 0 6 6 6 0 RNA helicase AAA_8 PF12780.7 KFP11284.1 - 5.6e-07 29.1 0.5 0.42 9.9 0.0 5.6 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 AAA_28 PF13521.6 KFP11284.1 - 7.1e-07 29.6 6.2 3 8.0 0.0 7.4 7 0 0 7 7 6 1 AAA domain Rad17 PF03215.15 KFP11284.1 - 8.6e-07 29.1 1.4 13 5.6 0.0 5.9 5 0 0 5 5 5 0 Rad17 P-loop domain PduV-EutP PF10662.9 KFP11284.1 - 9.7e-07 28.6 3.8 0.33 10.7 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 KFP11284.1 - 1.5e-06 28.0 3.7 5.3 6.8 0.0 6.2 6 0 0 6 6 6 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KFP11284.1 - 1.6e-06 27.8 0.6 13 5.6 0.0 6.3 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KFP11284.1 - 2.2e-06 28.1 1.6 3.8 7.8 0.0 5.9 5 0 0 5 5 5 0 AAA domain SRP54 PF00448.22 KFP11284.1 - 4e-06 26.6 0.8 6.1 6.4 0.0 5.2 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KFP11284.1 - 1.3e-05 24.9 7.1 1.4 8.5 0.0 5.7 6 0 0 6 6 5 1 AAA domain MMR_HSR1 PF01926.23 KFP11284.1 - 1.3e-05 25.2 0.5 12 6.1 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KFP11284.1 - 0.00013 21.8 2.4 5.3 6.7 0.0 5.9 6 0 0 6 6 6 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KFP11284.1 - 0.00016 21.7 0.0 10 5.9 0.0 5.4 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 KFP11284.1 - 0.00022 20.7 2.0 17 4.8 0.0 5.7 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP11284.1 - 0.00022 20.7 0.3 1.1 8.6 0.0 5.0 6 0 0 6 6 5 1 Bacterial TniB protein T2SSE PF00437.20 KFP11284.1 - 0.00023 20.3 5.0 9.4 5.2 0.0 5.9 6 0 0 6 6 6 0 Type II/IV secretion system protein CPT PF07931.12 KFP11284.1 - 0.00043 20.2 1.8 13 5.5 0.0 5.9 6 0 0 6 6 6 0 Chloramphenicol phosphotransferase-like protein MCM PF00493.23 KFP11284.1 - 0.00051 19.2 0.0 0.52 9.4 0.0 4.4 5 0 0 5 5 4 1 MCM P-loop domain DEAD PF00270.29 KFP11284.1 - 0.001 18.9 0.1 4 7.2 0.0 4.3 4 0 0 4 4 4 0 DEAD/DEAH box helicase dNK PF01712.19 KFP11284.1 - 0.0012 18.8 3.4 2.9 7.7 0.0 5.4 5 0 0 5 5 5 1 Deoxynucleoside kinase ATPase PF06745.13 KFP11284.1 - 0.011 15.1 0.6 3 7.1 0.0 3.8 3 0 0 3 3 3 0 KaiC CbiA PF01656.23 KFP11284.1 - 0.026 14.6 0.1 58 3.8 0.0 4.8 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_ab PF00006.25 KFP11284.1 - 0.062 13.0 0.0 9.6 5.8 0.0 3.5 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Ras PF00071.22 KFP11284.1 - 0.52 9.9 4.7 24 4.5 0.0 4.5 5 0 0 5 5 5 0 Ras family ATP_bind_1 PF03029.17 KFP11284.1 - 1.1 9.0 4.8 67 3.1 0.1 4.9 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 KFP11284.1 - 1.3 8.7 5.7 23 4.6 0.0 4.5 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KFP11284.1 - 2.1 7.9 5.5 37 3.9 0.0 4.3 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain FNIP_M PF14637.6 KFP11284.1 - 5 7.1 9.1 0.55 10.2 0.2 3.5 3 1 0 3 3 3 0 Folliculin-interacting protein middle domain NTPase_1 PF03266.15 KFP11284.1 - 9.6 6.1 6.9 98 2.8 0.0 4.6 6 0 0 6 6 4 0 NTPase HTH_AsnC-type PF13404.6 KFP11285.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Tachystatin_A PF11406.8 KFP11285.1 - 0.39 10.8 1.8 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A Connexin PF00029.19 KFP11286.1 - 4.2e-89 298.3 0.0 4.6e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Connexin BTB PF00651.31 KFP11287.1 - 3.8e-28 97.9 0.3 6.4e-28 97.2 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.17 KFP11287.1 - 4.6e-13 49.5 2.5 1.1e-12 48.3 2.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFP11287.1 - 1.3e-09 38.0 6.7 2.4e-09 37.1 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP11287.1 - 1.8e-05 24.7 7.5 3e-05 24.0 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF3342 PF11822.8 KFP11287.1 - 0.038 14.2 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase_Tyr PF07714.17 KFP11289.1 - 2.6e-59 200.6 0.0 4.3e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11289.1 - 8.2e-55 186.0 0.0 2.3e-54 184.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KFP11289.1 - 0.0052 16.7 0.3 0.014 15.4 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Lectin_N PF03954.14 KFP11289.1 - 2.9 7.6 7.6 0.11 12.2 0.7 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4462 PF14692.6 KFP11291.1 - 0.34 10.4 1.0 0.61 9.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Pkinase_Tyr PF07714.17 KFP11294.1 - 1.7e-97 325.8 0.0 2.6e-97 325.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP11294.1 - 7.3e-72 241.1 0.3 1.3e-71 240.3 0.3 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP11294.1 - 4.7e-46 157.3 0.0 7.8e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP11294.1 - 1.6e-29 102.1 8.1 1.9e-15 57.0 1.3 3.7 4 0 0 4 4 4 2 Fibronectin type III domain SAM_1 PF00536.30 KFP11294.1 - 3e-22 78.8 0.0 5.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP11294.1 - 4.8e-21 74.6 0.0 9.2e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFP11294.1 - 2.7e-20 73.0 0.0 6.1e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KFP11294.1 - 9.1e-06 25.3 10.4 9.1e-06 25.3 10.4 2.6 2 0 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFP11294.1 - 0.00024 21.6 2.9 0.00058 20.4 0.7 2.6 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFP11294.1 - 0.004 17.3 0.8 2.5 8.3 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Tissue_fac PF01108.17 KFP11294.1 - 0.0043 16.9 0.2 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 Tissue factor DUF2318 PF10080.9 KFP11294.1 - 0.009 16.1 1.9 0.033 14.3 1.9 1.9 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) Interfer-bind PF09294.10 KFP11294.1 - 0.0094 16.3 0.3 0.17 12.2 0.1 2.7 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF4998 PF16389.5 KFP11294.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Haspin_kinase PF12330.8 KFP11294.1 - 0.012 14.6 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Y_Y_Y PF07495.13 KFP11294.1 - 0.043 13.8 0.4 0.91 9.5 0.6 2.5 2 0 0 2 2 2 0 Y_Y_Y domain SusE PF14292.6 KFP11294.1 - 0.045 14.0 0.1 9.4 6.5 0.1 2.5 2 0 0 2 2 2 0 SusE outer membrane protein Kdo PF06293.14 KFP11294.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPI-anchored PF10342.9 KFP11294.1 - 0.12 13.2 0.1 1.2 9.9 0.2 2.4 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase_fungal PF17667.1 KFP11294.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PRIMA1 PF16101.5 KFP11294.1 - 1.5 8.8 5.1 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 EGF_MSP1_1 PF12946.7 KFP11294.1 - 2.5 8.2 6.6 0.36 10.9 1.7 2.1 2 0 0 2 2 2 0 MSP1 EGF domain 1 Glyco_hydro_99 PF16317.5 KFP11300.1 - 5.2e-170 565.1 11.2 6.1e-170 564.9 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 E3_UFM1_ligase PF09743.9 KFP11304.1 - 2.5e-106 355.3 0.1 2.5e-106 355.3 0.1 2.4 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 Tn7_Tnp_TnsA_C PF08721.11 KFP11304.1 - 0.55 10.9 4.4 1.2 9.9 0.0 3.7 4 1 1 5 5 5 0 TnsA endonuclease C terminal CelTOS PF18659.1 KFP11304.1 - 2.1 8.8 10.1 13 6.3 0.0 4.4 3 2 0 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites DUF3510 PF12022.8 KFP11304.1 - 7.8 6.9 7.0 91 3.4 3.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3510) LIM PF00412.22 KFP11305.1 - 3e-48 161.9 63.7 4.1e-12 46.1 5.9 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.21 KFP11307.1 - 4.1e-50 170.6 23.8 6e-50 170.0 23.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11307.1 - 4.7e-07 29.5 25.4 7.8e-07 28.7 25.4 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11307.1 - 0.0014 18.4 9.4 0.0014 18.4 9.4 3.0 3 0 0 3 3 3 1 Olfactory receptor DUF5527 PF17665.1 KFP11307.1 - 0.01 15.4 0.7 0.03 13.9 0.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5527) UPF0240 PF06784.11 KFP11309.1 - 9.7e-37 126.7 0.4 1.1e-36 126.5 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) RVT_1 PF00078.27 KFP11317.1 - 0.0034 16.9 0.0 0.0094 15.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.7 KFP11319.1 - 6.3e-09 36.0 16.2 0.0058 17.0 0.0 7.1 5 1 4 9 9 9 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KFP11319.1 - 4e-08 32.9 0.4 4e-08 32.9 0.4 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFP11319.1 - 6.8e-08 32.3 2.8 2.6e-07 30.4 2.8 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KFP11319.1 - 0.00034 20.4 7.7 3.7 7.8 0.1 6.3 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 KFP11319.1 - 0.00054 19.5 0.2 0.48 9.9 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFP11319.1 - 0.00095 18.9 5.5 0.6 9.9 0.0 4.7 3 2 2 5 5 5 3 Leucine rich repeat F-box_4 PF15966.5 KFP11319.1 - 0.0021 17.9 0.1 0.007 16.2 0.1 1.8 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 KFP11319.1 - 0.0054 17.1 17.9 2.3 9.1 0.2 7.3 7 1 0 7 7 7 2 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 KFP11319.1 - 0.26 11.1 0.9 0.5 10.2 0.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_N_4 PF17172.4 KFP11321.1 - 5.4e-31 107.3 0.0 9.7e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFP11321.1 - 4.2e-19 68.1 0.0 7.5e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP11321.1 - 4.6e-14 52.8 0.1 1.3e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KFP11321.1 - 5.6e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP11321.1 - 0.001 19.5 0.0 0.016 15.6 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.6 KFP11322.1 - 1.4e-20 73.7 0.0 1.8e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP11322.1 - 1.1e-19 70.9 0.0 6.4e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP11322.1 - 1.2e-15 58.1 0.0 1.9e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP11322.1 - 1.1e-14 54.9 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP11322.1 - 3.3e-13 49.7 0.0 4.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFP11322.1 - 1.5e-08 34.2 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KFP11322.1 - 8.6e-07 28.6 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KFP11322.1 - 8.3e-06 25.6 0.0 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KFP11322.1 - 1.5e-05 24.4 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFP11322.1 - 3.5e-05 23.4 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFP11322.1 - 0.00055 19.0 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KFP11322.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 KFP11322.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_PK PF05891.12 KFP11322.1 - 0.0073 15.9 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 KFP11322.1 - 0.057 13.4 0.1 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PNISR PF15996.5 KFP11323.1 - 9.5e-54 182.8 25.5 9.5e-54 182.8 25.5 5.8 2 2 3 5 5 5 1 Arginine/serine-rich protein PNISR UCH PF00443.29 KFP11324.1 - 1e-45 156.3 2.1 1.5e-45 155.7 2.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP11324.1 - 1.1e-17 64.1 8.8 1.1e-17 64.1 8.8 2.7 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein THOC7 PF05615.13 KFP11324.1 - 0.04 14.2 1.9 0.099 12.9 0.4 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 zf-4CXXC_R1 PF10497.9 KFP11324.1 - 0.41 10.9 10.6 0.053 13.7 3.2 2.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zinc_ribbon_9 PF14369.6 KFP11324.1 - 4.6 7.6 6.6 2.8 8.3 0.8 3.2 3 0 0 3 3 3 0 zinc-ribbon Rhodanese PF00581.20 KFP11325.1 - 2.8e-07 31.0 0.0 3.1e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain HK PF02110.15 KFP11325.1 - 0.095 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Cyclin_N PF00134.23 KFP11326.1 - 2.4e-14 53.2 3.7 7.9e-13 48.3 0.7 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFP11326.1 - 5.9e-07 29.8 0.3 2.2e-06 28.0 0.3 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 KFP11326.1 - 0.007 16.4 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KFP11326.1 - 0.0081 16.2 0.7 0.065 13.3 0.1 2.5 2 1 1 3 3 3 1 Cyclin, C-terminal domain SET PF00856.28 KFP11327.1 - 0.00027 21.4 0.0 0.00045 20.7 0.0 1.3 1 1 0 1 1 1 1 SET domain 7tm_1 PF00001.21 KFP11329.1 - 3.7e-46 157.6 21.1 4.4e-46 157.3 21.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11329.1 - 5e-07 29.7 13.2 5.5e-06 26.3 13.2 2.4 1 1 0 1 1 1 1 Olfactory receptor DUF3671 PF12420.8 KFP11329.1 - 0.21 11.7 0.0 0.21 11.7 0.0 3.6 2 2 1 3 3 3 0 Protein of unknown function Sec63 PF02889.16 KFP11331.1 - 7.6e-155 513.5 0.3 5.5e-83 278.1 0.1 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFP11331.1 - 5.6e-53 179.3 3.1 9e-27 94.0 0.5 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KFP11331.1 - 8.7e-26 90.9 0.0 1.3e-11 44.8 0.1 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP11331.1 - 4.5e-14 52.7 0.1 4.5e-07 30.2 0.0 3.7 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFP11331.1 - 1.2e-05 25.6 3.5 0.063 13.6 0.1 3.9 3 1 0 3 3 3 2 AAA domain Helicase_PWI PF18149.1 KFP11331.1 - 0.00013 22.1 0.0 0.00087 19.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain T2SSE PF00437.20 KFP11331.1 - 0.00022 20.4 0.0 0.91 8.5 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA PF00004.29 KFP11331.1 - 0.0011 19.4 0.6 0.83 10.1 0.0 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFP11331.1 - 0.0011 19.3 0.5 0.097 13.0 0.2 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KFP11331.1 - 0.0019 17.7 0.1 1.3 8.5 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 KFP11331.1 - 0.0066 16.0 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP11331.1 - 0.036 13.8 0.8 0.39 10.4 0.0 3.0 4 0 0 4 4 4 0 IstB-like ATP binding protein U62_UL91 PF17442.2 KFP11331.1 - 0.18 11.8 0.7 9.4 6.3 0.3 3.5 4 0 0 4 4 4 0 Functional domain of U62 and UL91 proteins AAA_23 PF13476.6 KFP11331.1 - 0.33 11.4 5.1 17 5.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain ANF_receptor PF01094.28 KFP11332.1 - 3.5e-82 276.3 0.0 5e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP11332.1 - 3.5e-55 186.0 0.2 5.4e-55 185.3 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP11332.1 - 8.6e-47 158.1 0.0 4.7e-46 155.7 0.0 2.3 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP11332.1 - 1e-17 64.3 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP11332.1 - 5.7e-09 36.1 0.0 1.4e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein TLV_coat PF00429.19 KFP11337.1 - 0.0034 16.1 0.1 0.0035 16.1 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) tRNA_U5-meth_tr PF05958.11 KFP11340.1 - 2.1e-12 46.7 0.1 9.5e-11 41.3 0.1 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KFP11340.1 - 1.4e-11 44.4 0.0 2.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP11340.1 - 4.1e-08 33.8 0.0 1.1e-07 32.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP11340.1 - 3.6e-06 26.6 0.0 7.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFP11340.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KFP11340.1 - 0.0031 16.9 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KFP11340.1 - 0.0044 17.0 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP11340.1 - 0.0047 17.5 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP11340.1 - 0.0077 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KFP11340.1 - 0.0097 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 KFP11340.1 - 0.017 14.9 0.0 0.067 13.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 KFP11340.1 - 0.022 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_12 PF08242.12 KFP11340.1 - 0.027 15.2 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 KFP11340.1 - 0.029 13.9 0.0 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 RRNA methyltransferase AviRa UPF0020 PF01170.18 KFP11340.1 - 0.085 12.5 0.3 0.25 11.0 0.3 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 KFP11340.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 KFP11340.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DoxX_2 PF13564.6 KFP11341.1 - 2.1e-07 31.0 2.0 3.3e-07 30.4 2.0 1.3 1 0 0 1 1 1 1 DoxX-like family DUF4131 PF13567.6 KFP11341.1 - 0.0068 16.1 0.7 0.2 11.3 0.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) SID-1_RNA_chan PF13965.6 KFP11341.1 - 0.018 13.5 0.6 0.023 13.1 0.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ac76 PF05814.11 KFP11341.1 - 0.16 12.0 1.7 0.18 11.8 0.2 1.8 2 0 0 2 2 2 0 Orf76 (Ac76) TPR_2 PF07719.17 KFP11342.1 - 4.7e-05 23.2 4.5 0.032 14.3 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP11342.1 - 0.023 14.4 2.6 1.8 8.3 0.2 2.7 3 0 0 3 3 3 0 TPR repeat TAFII55_N PF04658.13 KFP11343.1 - 9e-57 191.3 1.4 9e-57 191.3 1.4 2.2 2 1 0 2 2 2 1 TAFII55 protein conserved region CDO_I PF05995.12 KFP11343.1 - 1.2 8.4 0.0 1.2 8.4 0.0 2.9 4 0 0 4 4 4 0 Cysteine dioxygenase type I CHIP_TPR_N PF18391.1 KFP11343.1 - 1.7 9.5 22.1 14 6.6 2.5 3.8 2 1 1 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain Rep_4 PF05797.11 KFP11343.1 - 3.5 6.7 11.7 5.1 6.1 11.7 1.3 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) LMBR1 PF04791.16 KFP11343.1 - 6.8 5.5 6.8 7.1 5.4 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mg_trans_NIPA PF05653.14 KFP11344.1 - 3.8e-123 410.3 16.1 4.2e-123 410.2 16.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP11344.1 - 3.1e-07 30.6 6.2 3.1e-07 30.6 6.2 3.1 2 1 0 2 2 2 1 EamA-like transporter family COX6C PF02937.15 KFP11344.1 - 0.099 12.8 0.2 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc Multi_Drug_Res PF00893.19 KFP11344.1 - 2.2 9.0 11.8 0.22 12.2 1.9 3.4 1 1 1 3 3 3 0 Small Multidrug Resistance protein DUF4064 PF13273.6 KFP11344.1 - 5.9 7.2 23.2 0.31 11.3 7.7 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) Pkinase_Tyr PF07714.17 KFP11345.1 - 7.3e-88 294.2 0.0 9.8e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11345.1 - 1.5e-43 149.1 0.0 1.9e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP11345.1 - 3.9e-23 81.3 0.1 8.2e-23 80.3 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP11345.1 - 2e-13 49.7 0.0 4.5e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFP11345.1 - 2e-13 50.7 0.3 5.5e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFP11345.1 - 1e-10 41.2 2.7 2.6e-10 39.9 2.7 1.7 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.6 KFP11345.1 - 2.9e-07 30.2 0.1 6.4e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP11345.1 - 1.3e-05 24.8 0.0 3.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 KFP11345.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_3 PF14593.6 KFP11345.1 - 0.003 17.6 0.7 0.0085 16.2 0.4 1.9 2 1 0 2 2 1 1 PH domain Pkinase_fungal PF17667.1 KFP11345.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP11345.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SH3_3 PF08239.11 KFP11345.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain APH PF01636.23 KFP11345.1 - 0.041 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP11345.1 - 0.05 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_10 PF17902.1 KFP11345.1 - 0.067 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Ribosomal_L44 PF00935.19 KFP11346.1 - 4.2e-39 132.9 9.3 4.2e-39 132.9 9.3 1.6 1 1 1 2 2 2 1 Ribosomal protein L44 SVWC PF15430.6 KFP11346.1 - 0.046 14.0 1.6 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Single domain von Willebrand factor type C Melibiase_2 PF16499.5 KFP11347.1 - 1.4e-133 444.4 2.8 2.8e-133 443.4 2.8 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 KFP11347.1 - 2.6e-28 98.1 0.0 4.3e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 KFP11347.1 - 2.3e-05 23.6 0.0 4.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_C PF17801.1 KFP11347.1 - 0.00013 22.0 0.4 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Myelin_PLP PF01275.19 KFP11348.1 - 1.1e-104 349.5 13.2 1.4e-104 349.2 13.2 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Comm PF15957.5 KFP11348.1 - 0.087 13.2 0.2 0.22 11.9 0.2 1.6 1 0 0 1 1 1 0 Commissureless Ras PF00071.22 KFP11349.1 - 1.5e-56 190.5 0.0 2e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11349.1 - 3.3e-30 104.8 0.0 5e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11349.1 - 7.2e-10 38.6 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP11349.1 - 2.6e-06 27.5 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP11349.1 - 1.4e-05 24.6 0.0 2.2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP11349.1 - 1.5e-05 24.9 0.1 0.012 15.5 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP11349.1 - 0.00017 21.2 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP11349.1 - 0.0067 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KFP11349.1 - 0.035 14.5 0.0 0.055 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFP11349.1 - 0.097 11.8 1.3 3 6.9 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 KFP11349.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Pribosyltran_N PF13793.6 KFP11350.1 - 1.7e-48 163.4 0.5 6e-48 161.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFP11350.1 - 1.1e-44 152.6 2.5 7.8e-38 130.3 1.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFP11350.1 - 1.3e-13 50.8 2.4 1.9e-13 50.2 0.5 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFP11350.1 - 0.00038 20.0 0.1 0.00065 19.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Lar_N PF09861.9 KFP11350.1 - 0.12 11.5 1.0 0.39 9.8 0.0 2.2 3 0 0 3 3 3 0 Lactate racemase N-terminal domain FERM_N PF09379.10 KFP11352.1 - 6e-05 22.9 0.0 8.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FERM N-terminal domain FERM_f0 PF16511.5 KFP11352.1 - 0.02 15.2 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM PIH1_CS PF18201.1 KFP11353.1 - 2e-11 44.1 0.0 2.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 PIH1 CS-like domain 7tm_1 PF00001.21 KFP11354.1 - 3.8e-55 187.1 18.5 3.8e-55 187.1 18.5 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11354.1 - 4e-05 23.1 25.2 0.0068 15.8 5.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11354.1 - 9.5e-05 22.3 14.9 0.00017 21.5 14.9 1.3 1 0 0 1 1 1 1 Olfactory receptor CBP_BcsG PF11658.8 KFP11354.1 - 0.032 12.6 0.4 0.056 11.8 0.4 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pyr_redox_2 PF07992.14 KFP11355.1 - 2.2e-49 168.3 0.2 4.3e-49 167.3 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP11355.1 - 4.7e-35 120.2 0.5 8.3e-35 119.4 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP11355.1 - 1.9e-18 66.8 0.0 4.2e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP11355.1 - 6.5e-09 35.5 0.0 9.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP11355.1 - 0.0067 15.6 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Metallophos PF00149.28 KFP11356.1 - 2.5e-35 122.8 0.6 3.8e-35 122.3 0.5 1.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFP11356.1 - 0.017 14.7 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KFP11356.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) PurA PF04845.13 KFP11357.1 - 1.4e-97 325.4 0.6 3e-97 324.2 0.6 1.5 1 1 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 KFP11357.1 - 0.0069 16.5 2.6 4 7.6 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) NYAP_N PF15439.6 KFP11358.1 - 5e-136 454.0 38.2 5e-136 454.0 38.2 3.9 2 2 1 3 3 3 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NYAP_C PF15452.6 KFP11358.1 - 4.4e-42 144.8 14.5 1.3e-41 143.3 14.5 1.8 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DHR-2 PF06920.13 KFP11359.1 - 2.4e-209 696.4 11.2 2.4e-209 696.4 11.2 2.4 3 0 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP11359.1 - 5.1e-56 189.6 0.7 2.3e-55 187.5 0.4 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFP11359.1 - 5.8e-36 123.3 1.2 1.8e-35 121.7 1.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 KFP11359.1 - 3.5e-13 50.0 0.6 2e-12 47.5 0.6 2.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFP11359.1 - 0.0047 17.3 0.1 0.04 14.3 0.1 2.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 KFP11359.1 - 0.025 14.8 0.0 0.083 13.2 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Cullin PF00888.22 KFP11360.1 - 2e-227 756.7 9.5 2.4e-227 756.4 9.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP11360.1 - 1.7e-27 95.2 1.1 1.7e-27 95.2 1.1 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_antitermQ PF06530.12 KFP11360.1 - 0.0087 16.0 0.2 0.05 13.5 0.1 2.4 2 0 0 2 2 2 1 Phage antitermination protein Q RhgB_N PF09284.10 KFP11360.1 - 0.047 13.2 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Phage_TAC_12 PF12363.8 KFP11360.1 - 0.055 13.9 0.8 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC RuvB_C PF05491.13 KFP11360.1 - 0.83 9.6 2.7 1e+02 2.9 0.0 4.4 4 0 0 4 4 4 0 RuvB C-terminal winged helix domain Glyco_hydro_4C PF11975.8 KFP11360.1 - 1.6 8.8 8.8 1.8 8.6 1.6 3.6 3 1 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain WAC_Acf1_DNA_bd PF10537.9 KFP11360.1 - 2.4 8.7 7.1 0.93 10.1 0.3 3.4 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal FAM124 PF15067.6 KFP11361.1 - 8.3e-107 356.2 0.2 9.2e-107 356.0 0.2 1.0 1 0 0 1 1 1 1 FAM124 family TPR_7 PF13176.6 KFP11361.1 - 0.069 13.2 0.1 0.37 10.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Serpin PF00079.20 KFP11362.1 - 5.9e-110 368.1 0.0 6.7e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FYVE PF01363.21 KFP11363.1 - 2.5e-14 53.2 7.6 2.5e-14 53.2 7.6 1.8 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 KFP11363.1 - 4.3e-14 52.7 21.4 4.8e-06 27.2 1.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11363.1 - 3.1e-05 24.2 0.4 0.22 11.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP11363.1 - 0.00036 19.4 1.4 1.1 7.9 0.3 3.4 2 1 1 3 3 3 2 Nup133 N terminal like ELYS-bb PF16687.5 KFP11363.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin IBR PF01485.21 KFP11363.1 - 0.89 9.8 12.1 4.8 7.5 0.6 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 KFP11363.1 - 1.3 9.3 8.2 3.8 7.7 8.2 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger Clat_adaptor_s PF01217.20 KFP11364.1 - 6.8e-43 146.0 2.1 7.4e-43 145.9 2.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Granin PF01271.17 KFP11365.1 - 3.4e-121 406.0 33.4 3.8e-121 405.9 33.4 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) IF2_N PF04760.15 KFP11365.1 - 0.0026 17.5 0.7 1.3 8.9 0.1 3.3 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region ISK_Channel PF02060.15 KFP11366.1 - 2.3e-10 40.2 0.1 3e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Slow voltage-gated potassium channel AMP-binding PF00501.28 KFP11367.1 - 2.8e-102 342.5 0.2 3.7e-102 342.1 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP11367.1 - 5.7e-06 27.2 0.1 2.2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DAGAT PF03982.13 KFP11368.1 - 4.5e-121 403.3 0.2 5.7e-121 403.0 0.2 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase tRNA_synthFbeta PF17759.1 KFP11369.1 - 5.3e-52 176.4 0.0 7.6e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 KFP11369.1 - 9.2e-28 97.1 0.1 1.7e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 KFP11369.1 - 4.6e-25 87.6 1.0 3.8e-24 84.7 0.5 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KFP11369.1 - 1.1e-15 57.7 0.0 4.6e-13 49.3 0.0 3.5 4 0 0 4 4 4 1 tRNA synthetase B5 domain Glyco_hydro_77 PF02446.17 KFP11369.1 - 0.26 10.1 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase PAP2 PF01569.21 KFP11370.1 - 7.5e-15 54.9 4.6 7.5e-15 54.9 4.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFP11370.1 - 5.5e-05 23.0 6.3 0.00011 22.0 5.9 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KFP11370.1 - 0.03 14.4 2.1 0.1 12.7 0.3 2.3 1 1 1 2 2 2 0 Divergent PAP2 family PAX PF00292.18 KFP11371.1 - 9.4e-37 125.7 0.4 1.6e-36 125.0 0.4 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax7 PF12360.8 KFP11371.1 - 1.8e-25 88.9 6.8 3.7e-25 87.9 6.8 1.6 1 0 0 1 1 1 1 Paired box protein 7 Homeodomain PF00046.29 KFP11371.1 - 6.9e-23 80.3 6.9 1.3e-22 79.3 6.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP11371.1 - 0.00021 21.1 1.4 0.00056 19.8 0.7 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 KFP11371.1 - 0.09 12.6 2.2 0.38 10.6 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KFP11371.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 InsA C-terminal domain Pkinase_Tyr PF07714.17 KFP11372.1 - 2.9e-97 325.0 0.0 3.3e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11372.1 - 3.7e-46 157.6 0.0 4.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP11372.1 - 1e-14 55.2 1.1 1.8e-14 54.3 1.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP11372.1 - 0.0048 15.9 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP11372.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 KFP11373.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP11373.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFP11374.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) His_Phos_2 PF00328.22 KFP11375.1 - 1.2e-31 110.4 0.0 3.1e-31 109.1 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-C3HC4_5 PF17121.5 KFP11375.1 - 0.11 12.4 2.3 0.18 11.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.28 KFP11376.1 - 1.2e-18 67.4 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFP11376.1 - 8.6e-10 38.8 3.4 1.7e-09 37.8 3.4 1.5 1 0 0 1 1 1 1 SOCS box HELP PF03451.14 KFP11376.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 HELP motif fn3 PF00041.21 KFP11378.1 - 2.5e-08 34.1 0.1 4.6e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-B_box PF00643.24 KFP11378.1 - 3.7e-07 30.2 5.2 3.7e-07 30.2 5.2 7.6 7 2 0 7 7 7 3 B-box zinc finger AbiGii_2 PF16873.5 KFP11378.1 - 0.00041 19.2 2.2 0.00065 18.5 2.2 1.3 1 0 0 1 1 1 1 Putative abortive phage resistance protein AbiGii toxin Pur_ac_phosph_N PF16656.5 KFP11378.1 - 0.039 14.5 0.1 0.08 13.5 0.1 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Cadherin PF00028.17 KFP11379.1 - 8.9e-16 58.1 0.2 4.2e-10 39.9 0.5 2.7 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFP11379.1 - 0.0004 20.6 0.0 0.00068 19.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily V_ATPase_I PF01496.19 KFP11379.1 - 0.00057 18.0 1.9 0.00092 17.3 1.9 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM132D_C PF15706.5 KFP11379.1 - 0.0035 17.1 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SpoIIIAH PF12685.7 KFP11379.1 - 0.005 16.7 4.2 0.0084 16.0 4.2 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein SID-1_RNA_chan PF13965.6 KFP11379.1 - 0.019 13.4 1.6 0.027 12.9 1.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Myc_N PF01056.18 KFP11379.1 - 0.022 14.7 7.5 0.034 14.0 7.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Chordopox_A13L PF05961.11 KFP11379.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Zip PF02535.22 KFP11379.1 - 1.4 8.1 5.4 2.1 7.5 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 KFP11379.1 - 3 7.0 7.9 5.5 6.1 7.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Lipocalin PF00061.23 KFP11380.1 - 6.8e-18 65.3 0.3 8.1e-18 65.0 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP11380.1 - 2.5e-05 24.2 0.2 3.1e-05 23.9 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFP11381.1 - 1.3e-19 70.9 5.2 1.4e-19 70.7 5.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP11381.1 - 3.6e-08 33.4 1.0 4.4e-08 33.1 1.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Coatomer_WDAD PF04053.14 KFP11382.1 - 2.1e-170 567.6 0.0 3.6e-170 566.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KFP11382.1 - 3.4e-41 138.5 8.1 1.3e-09 38.5 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11382.1 - 6.7e-07 29.5 0.6 0.63 10.4 0.1 6.1 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain MetallophosC PF16370.5 KFP11382.1 - 0.07 13.4 0.0 0.6 10.3 0.0 2.2 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Forkhead PF00250.18 KFP11383.1 - 7.8e-40 135.0 0.0 9e-40 134.8 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain PI3Ka PF00613.20 KFP11384.1 - 3.9e-62 208.9 1.1 8.3e-62 207.9 1.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP11384.1 - 1.8e-59 201.6 0.0 4.2e-59 200.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 KFP11384.1 - 1.3e-33 114.6 0.1 4.4e-33 112.8 0.1 2.0 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 KFP11384.1 - 3.5e-31 107.5 0.1 8.9e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFP11384.1 - 1.8e-19 70.1 0.0 3.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP11384.1 - 0.034 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RWD PF05773.22 KFP11384.1 - 0.058 13.7 0.9 17 5.7 0.1 3.0 3 0 0 3 3 3 0 RWD domain Period_C PF12114.8 KFP11386.1 - 4.1e-93 310.4 6.4 4.1e-93 310.4 6.4 4.2 4 0 0 4 4 4 1 Period protein 2/3C-terminal region PAS_3 PF08447.12 KFP11386.1 - 1.7e-12 47.4 0.0 5.2e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KFP11386.1 - 1.4e-08 34.9 0.0 5.7e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KFP11386.1 - 8.7e-06 25.7 0.0 0.00038 20.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold Hairy_orange PF07527.13 KFP11387.1 - 1.5e-11 44.3 0.1 3e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Hairy Orange HLH PF00010.26 KFP11387.1 - 5.2e-11 42.3 0.0 2.3e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mo25 PF08569.11 KFP11388.1 - 1e-142 475.3 16.6 1.2e-142 475.2 16.6 1.0 1 0 0 1 1 1 1 Mo25-like BRICHOS PF04089.14 KFP11389.1 - 3e-22 78.7 0.0 4.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain CDC50 PF03381.15 KFP11389.1 - 0.2 11.2 0.3 0.34 10.4 0.3 1.3 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family 7tm_1 PF00001.21 KFP11390.1 - 1.6e-32 112.9 20.9 1.9e-32 112.7 20.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CAML PF14963.6 KFP11390.1 - 0.86 9.7 2.9 1.4 8.9 2.9 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand 7tm_1 PF00001.21 KFP11391.1 - 4e-31 108.3 19.5 4.9e-31 108.0 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0542 PF15086.6 KFP11391.1 - 1.2 9.1 5.3 1.8 8.5 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 7tm_1 PF00001.21 KFP11392.1 - 2.6e-31 108.9 24.6 3.1e-31 108.7 24.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11392.1 - 0.00032 20.2 24.2 0.00038 19.9 24.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP11392.1 - 6.9 6.2 30.5 0.17 11.5 20.6 2.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFP11393.1 - 1.9e-22 79.9 10.1 2.3e-22 79.6 10.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11393.1 - 0.0001 21.8 4.8 0.00014 21.3 4.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP11393.1 - 0.00098 18.8 9.8 0.0014 18.3 9.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFP11394.1 - 4.4e-28 98.3 7.8 4.9e-28 98.2 7.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.12 KFP11394.1 - 5.2 7.3 9.1 4.9 7.4 0.0 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF1201 PF06716.11 KFP11394.1 - 7 6.8 13.3 0.15 12.1 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Glyco_transf_29 PF00777.18 KFP11395.1 - 2.6e-38 132.0 0.0 4.9e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) C1q PF00386.21 KFP11396.1 - 1.3e-40 138.6 0.5 1.6e-40 138.3 0.5 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP11396.1 - 1.1e-10 41.1 32.2 1.2e-09 37.8 32.2 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP11396.1 - 0.0047 16.8 0.0 0.0067 16.3 0.0 1.1 1 0 0 1 1 1 1 BclA C-terminal domain OTOS PF15182.6 KFP11397.1 - 6.8e-27 93.2 2.5 7.2e-27 93.1 2.5 1.0 1 0 0 1 1 1 1 Otospiralin DUF3330 PF11809.8 KFP11397.1 - 0.015 15.3 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Glypican PF01153.19 KFP11398.1 - 6.4e-109 365.3 2.2 7.2e-109 365.1 2.2 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFP11398.1 - 0.062 13.9 0.3 0.062 13.9 0.3 2.1 2 0 0 2 2 2 0 Fz domain Spore_III_AB PF09548.10 KFP11398.1 - 0.22 11.6 2.1 3.2 7.8 0.5 2.6 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DSPc PF00782.20 KFP11400.1 - 3.7e-29 101.2 0.0 4e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFP11400.1 - 0.068 13.5 0.0 0.098 13.0 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain DSPn PF14671.6 KFP11400.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PMP22_Claudin PF00822.20 KFP11401.1 - 2.3e-35 121.9 12.2 2.9e-35 121.6 12.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP11401.1 - 4.7e-10 39.5 12.1 9.1e-09 35.3 12.1 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP11401.1 - 1.6 8.6 12.7 0.17 11.7 5.5 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein Rhomboid PF01694.22 KFP11402.1 - 3.2e-27 95.4 17.0 1.2e-26 93.5 15.2 2.1 2 0 0 2 2 2 1 Rhomboid family Caps_synth_CapC PF14102.6 KFP11402.1 - 0.63 10.5 6.3 0.21 12.0 3.3 1.8 2 0 0 2 2 2 0 Capsule biosynthesis CapC Kelch_1 PF01344.25 KFP11403.1 - 2.1e-44 148.8 24.5 8e-14 51.0 0.1 7.2 7 1 0 7 7 7 6 Kelch motif BACK PF07707.15 KFP11403.1 - 2.2e-32 111.2 0.8 2.2e-32 111.2 0.8 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP11403.1 - 6.9e-29 99.2 8.7 1.8e-05 24.9 0.0 6.6 3 1 3 6 6 6 6 Kelch motif BTB PF00651.31 KFP11403.1 - 7.9e-29 100.1 1.5 1.7e-28 99.0 0.8 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 KFP11403.1 - 8.6e-26 89.7 3.6 5.2e-05 23.4 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP11403.1 - 3.2e-21 75.1 1.4 0.00031 20.7 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP11403.1 - 9.9e-21 72.9 12.5 1.3e-05 24.9 0.1 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP11403.1 - 2.6e-08 33.7 9.0 0.094 12.7 0.1 5.8 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFP11403.1 - 0.012 15.7 0.6 0.034 14.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) Kelch_1 PF01344.25 KFP11404.1 - 1.3e-36 123.9 6.5 6.1e-12 44.9 0.1 6.9 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP11404.1 - 1.1e-31 109.0 0.3 2.4e-31 107.9 0.3 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP11404.1 - 6.1e-29 99.3 0.1 6.8e-06 26.2 0.0 6.1 3 2 3 6 6 6 5 Kelch motif BTB PF00651.31 KFP11404.1 - 1e-27 96.5 5.0 4.2e-27 94.6 2.4 2.6 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP11404.1 - 4.5e-27 93.0 1.0 1.5e-05 24.7 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP11404.1 - 2.8e-14 52.8 0.3 0.1 12.6 0.0 6.5 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP11404.1 - 4.6e-14 52.3 1.8 0.0051 17.1 0.0 6.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP11404.1 - 9.7e-11 41.4 1.6 0.00055 19.8 0.1 5.6 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 KFP11404.1 - 0.00022 21.3 3.2 0.0018 18.5 0.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) 7tm_1 PF00001.21 KFP11405.1 - 2e-07 30.6 27.9 5.5e-07 29.2 27.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11405.1 - 0.0034 17.2 21.7 0.007 16.1 21.7 1.6 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP11405.1 - 3.3 7.3 32.1 0.058 13.0 16.5 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP11405.1 - 4.1 6.7 30.7 16 4.8 30.8 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx RhoGEF PF00621.20 KFP11406.1 - 9e-47 159.7 6.3 9e-47 159.7 6.3 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP11406.1 - 7.4e-11 42.5 0.7 1.6e-10 41.5 0.7 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFP11406.1 - 3.7e-10 39.2 1.9 6.8e-10 38.4 1.9 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP11406.1 - 3.6e-09 36.3 0.1 6.7e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP11406.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Cor1 PF04803.12 KFP11406.1 - 0.84 9.8 8.5 0.62 10.3 0.8 3.1 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region TCRP1 PF14944.6 KFP11408.1 - 1.4e-108 362.5 66.0 4.7e-87 292.0 44.1 2.0 1 1 1 2 2 2 2 Tongue Cancer Chemotherapy Resistant Protein 1 PH PF00169.29 KFP11409.1 - 1.1e-10 42.0 0.3 1.4e-10 41.6 0.3 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP11409.1 - 0.0019 18.6 0.4 0.0052 17.2 0.4 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain APS_kinase PF01583.20 KFP11411.1 - 5.6e-75 250.6 0.0 8.7e-75 249.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFP11411.1 - 2.3e-70 236.4 0.1 3.3e-70 235.9 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFP11411.1 - 4.1e-50 169.6 0.0 7.5e-50 168.7 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFP11411.1 - 2.2e-07 31.1 0.0 5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP11411.1 - 0.00036 21.1 0.0 0.0016 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 KFP11411.1 - 0.032 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase KTI12 PF08433.10 KFP11411.1 - 0.039 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 KFP11411.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.6 KFP11411.1 - 0.045 14.0 0.1 0.56 10.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.20 KFP11411.1 - 0.046 12.4 0.1 0.63 8.6 0.1 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Zeta_toxin PF06414.12 KFP11411.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 KFP11411.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PAP2_C PF14360.6 KFP11413.1 - 8.5e-28 96.7 14.3 8.5e-28 96.7 14.3 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KFP11413.1 - 2.9e-05 23.9 12.7 2.9e-05 23.9 12.7 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFP11413.1 - 0.29 10.8 16.6 0.2 11.3 12.1 2.3 2 1 0 2 2 2 0 PAP2 superfamily p450 PF00067.22 KFP11414.1 - 9.5e-106 354.3 0.2 1.1e-105 354.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.18 KFP11415.1 - 4.6e-53 179.8 3.6 6.1e-53 179.4 3.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFP11415.1 - 2.2e-35 121.1 0.0 5.1e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain CTNNB1_binding PF08347.11 KFP11416.1 - 5.1e-52 177.0 8.2 5.1e-52 177.0 8.2 2.1 2 0 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFP11416.1 - 5.3e-22 78.0 0.7 5.3e-22 78.0 0.7 2.5 3 1 1 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP11416.1 - 6e-09 36.4 0.8 1.8e-08 34.9 0.8 1.8 1 0 0 1 1 1 1 HMG-box domain Ribosomal_L34e PF01199.18 KFP11417.1 - 6e-43 145.1 7.3 7.6e-43 144.8 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e OST3_OST6 PF04756.13 KFP11418.1 - 0.00033 20.1 0.1 0.00039 19.9 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family MCU PF04678.13 KFP11422.1 - 1.9e-64 217.0 3.3 2.5e-64 216.6 3.3 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Peptidase_C14 PF00656.22 KFP11423.1 - 6.3e-55 186.8 0.1 7.6e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 Caspase domain PLA2G12 PF06951.11 KFP11424.1 - 5.2e-61 205.7 10.0 5.7e-61 205.6 10.0 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_2 PF05826.12 KFP11424.1 - 2.9 8.2 16.5 1.4 9.2 2.4 2.5 1 1 2 3 3 3 0 Phospholipase A2 Trypsin PF00089.26 KFP11425.1 - 1e-58 198.7 1.2 2e-58 197.8 1.2 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFP11425.1 - 9.3e-15 54.6 28.9 1.4e-08 34.8 13.0 4.5 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A SRCR PF00530.18 KFP11425.1 - 2.3e-10 40.9 2.9 2.3e-10 40.9 2.9 3.6 3 1 1 4 4 4 1 Scavenger receptor cysteine-rich domain Kazal_2 PF07648.15 KFP11425.1 - 5.2e-07 29.7 5.1 5.2e-07 29.7 5.1 2.9 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Trypsin_2 PF13365.6 KFP11425.1 - 2.4e-05 25.3 0.0 4.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain SRCR_2 PF15494.6 KFP11425.1 - 0.00017 22.1 3.6 0.00017 22.1 3.6 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Gar1 PF04410.14 KFP11426.1 - 3.2e-38 130.9 0.0 3.9e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.21 KFP11427.1 - 2e-42 145.3 16.1 2.4e-42 145.1 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11427.1 - 5.3e-11 42.4 13.8 6.5e-11 42.1 13.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx NOT2_3_5 PF04153.18 KFP11427.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family TMEM223 PF14640.6 KFP11427.1 - 0.18 12.0 3.5 0.39 10.9 0.9 2.4 2 1 0 2 2 2 0 Transmembrane protein 223 FtsK_4TM PF13491.6 KFP11427.1 - 1.1 9.0 6.6 0.53 10.0 3.8 1.9 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE LRR_8 PF13855.6 KFP11428.1 - 4.3e-25 87.3 10.7 1.7e-10 40.5 0.5 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP11428.1 - 7.9e-15 54.7 5.8 5.6e-10 39.3 1.4 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 KFP11428.1 - 2.5e-14 53.6 0.4 6.4e-14 52.3 0.4 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP11428.1 - 4.4e-11 42.7 0.0 9.2e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP11428.1 - 6.1e-10 39.3 0.4 2.8e-09 37.2 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFP11428.1 - 3.1e-07 30.0 2.4 0.49 11.1 0.1 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 KFP11428.1 - 2.7e-06 27.4 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFP11428.1 - 2.1e-05 24.6 0.2 5.7e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.6 KFP11428.1 - 0.00052 19.6 0.1 0.019 14.5 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.17 KFP11428.1 - 0.00061 19.9 0.1 0.012 15.8 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRRNT PF01462.18 KFP11428.1 - 0.014 15.0 5.1 0.33 10.7 1.7 3.3 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain C2-set_2 PF08205.12 KFP11428.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain LRR_6 PF13516.6 KFP11428.1 - 0.19 11.8 0.2 0.19 11.8 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Ldl_recept_b PF00058.17 KFP11429.1 - 1.1e-44 150.6 11.3 6.5e-09 36.1 0.0 8.9 10 0 0 10 10 10 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP11429.1 - 4.5e-36 122.8 149.7 8.7e-09 35.5 6.8 11.6 11 0 0 11 11 11 7 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP11429.1 - 3.1e-34 116.5 77.1 1.7e-05 24.7 4.2 11.4 11 0 0 11 11 11 9 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP11429.1 - 3.5e-20 71.9 52.4 2.7e-07 30.7 9.7 11.6 10 1 1 11 11 11 5 Calcium-binding EGF domain EGF PF00008.27 KFP11429.1 - 1e-19 70.4 122.7 3e-05 24.2 6.7 11.3 11 0 0 11 11 11 7 EGF-like domain EGF_3 PF12947.7 KFP11429.1 - 4.4e-14 52.4 130.3 3.9e-06 26.9 11.2 10.9 10 0 0 10 10 10 6 EGF domain DUF5050 PF16472.5 KFP11429.1 - 7.1e-10 38.6 0.0 3.9e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) SGL PF08450.12 KFP11429.1 - 3.9e-06 26.6 0.1 1.1 8.8 0.0 4.7 3 1 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 KFP11429.1 - 0.0012 19.4 98.3 0.026 15.2 6.8 10.9 9 0 0 9 9 9 4 Human growth factor-like EGF ELO PF01151.18 KFP11430.1 - 6.4e-68 229.0 23.0 7.5e-68 228.8 23.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_M1 PF01433.20 KFP11432.1 - 1.6e-89 299.2 1.5 2.7e-89 298.5 1.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFP11432.1 - 1.4e-82 277.8 5.8 1.4e-82 277.8 5.8 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFP11432.1 - 2.7e-55 187.4 1.3 4.3e-55 186.8 0.8 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF1570 PF07607.11 KFP11432.1 - 0.021 15.1 0.1 0.082 13.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) PetM PF08041.11 KFP11432.1 - 2.4 7.8 5.1 4.4 7.0 5.1 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 OAR PF03826.17 KFP11434.1 - 4.4e-09 35.9 1.2 1e-08 34.7 1.2 1.7 1 0 0 1 1 1 1 OAR domain Homeodomain PF00046.29 KFP11434.1 - 0.084 12.7 7.7 0.14 12.0 7.7 1.4 1 0 0 1 1 1 0 Homeodomain DUF4605 PF15378.6 KFP11435.1 - 1.4e-25 88.9 6.3 1.9e-25 88.4 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) PHO4 PF01384.20 KFP11436.1 - 2.6e-139 464.0 8.4 3.3e-139 463.6 8.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Vpu PF00558.19 KFP11436.1 - 0.0098 15.6 0.3 0.0098 15.6 0.3 2.1 2 0 0 2 2 2 1 Vpu protein Pkinase_Tyr PF07714.17 KFP11438.1 - 1.6e-09 37.5 0.1 2.5e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11438.1 - 2.5e-06 27.1 0.0 9e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain PIP49_C PF12260.8 KFP11438.1 - 0.0027 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFP11438.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 TPR_19 PF14559.6 KFP11439.1 - 0.15 12.6 0.2 0.41 11.2 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CHGN PF05679.16 KFP11440.1 - 3.6e-80 270.2 1.0 4.7e-80 269.9 1.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP11440.1 - 3.9e-09 36.1 1.2 8.6e-09 34.9 1.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP11440.1 - 5.9e-05 22.7 0.6 0.00021 20.8 0.6 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFP11440.1 - 0.0024 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cnn_1N PF07989.11 KFP11440.1 - 1.2 9.4 5.3 0.92 9.7 0.6 2.7 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 KFP11440.1 - 1.2 9.5 4.1 0.84 10.0 1.1 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain SH2 PF00017.24 KFP11441.1 - 1.4e-13 50.7 0.1 2.7e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 SH2 domain Glyco_trans_1_2 PF13524.6 KFP11441.1 - 7.9 7.0 6.2 7.6 7.0 0.4 3.1 3 0 0 3 3 3 0 Glycosyl transferases group 1 Sulfotransfer_1 PF00685.27 KFP11442.1 - 1.6e-91 306.5 0.3 1.8e-91 306.3 0.3 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11442.1 - 1.4e-12 48.4 0.0 5.9e-09 36.6 0.0 2.4 1 1 0 2 2 2 2 Sulfotransferase family HTH_Tnp_Tc3_2 PF01498.18 KFP11442.1 - 0.0082 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Transposase Sulphotransf PF09037.10 KFP11442.1 - 0.033 13.7 0.2 0.3 10.6 0.1 2.3 3 0 0 3 3 3 0 Stf0 sulphotransferase DUF4576 PF15144.6 KFP11442.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) UCR_14kD PF02271.16 KFP11442.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Sulfotransfer_1 PF00685.27 KFP11443.1 - 2.1e-84 283.2 0.0 2.4e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11443.1 - 8.4e-06 26.3 0.2 0.0072 16.7 0.1 2.4 1 1 0 2 2 2 2 Sulfotransferase family YTH PF04146.15 KFP11444.1 - 2.3e-41 141.5 0.1 2.3e-41 141.5 0.1 3.8 2 2 0 2 2 2 1 YT521-B-like domain ThiF PF00899.21 KFP11445.1 - 2.3e-96 321.9 0.0 3.2e-64 216.6 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFP11445.1 - 1.5e-80 270.8 2.8 2.2e-80 270.2 2.8 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFP11445.1 - 7.6e-26 90.1 0.0 1.8e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KFP11445.1 - 1.7e-15 56.9 0.8 6e-15 55.2 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 KFP11445.1 - 4e-14 53.1 0.0 1.1e-13 51.6 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain SH2 PF00017.24 KFP11446.1 - 1.7e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFP11446.1 - 6e-05 23.5 0.2 0.00022 21.7 0.1 1.9 1 1 1 2 2 2 1 PH domain PH_11 PF15413.6 KFP11446.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 KFP11447.1 - 7.1e-100 333.6 0.0 8.3e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11447.1 - 1.7e-49 168.6 0.0 2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP11447.1 - 1.3e-15 58.0 0.3 2.4e-15 57.2 0.3 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP11447.1 - 0.0033 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP11447.1 - 0.0097 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP11447.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Steroid_dh PF02544.16 KFP11448.1 - 2.2e-19 69.9 6.7 2.2e-19 69.9 6.7 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase RVT_1 PF00078.27 KFP11450.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SKI PF01202.22 KFP11452.1 - 0.0002 21.5 0.0 0.00082 19.5 0.0 1.8 1 1 0 1 1 1 1 Shikimate kinase ubiquitin PF00240.23 KFP11453.1 - 5e-13 48.6 0.4 9e-13 47.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KFP11453.1 - 5.4e-10 39.0 61.1 0.00013 21.9 10.2 6.5 3 2 3 6 6 6 5 STI1 domain UBA PF00627.31 KFP11453.1 - 7.6e-08 32.1 0.3 2.3e-07 30.6 0.3 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFP11453.1 - 0.0021 17.9 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RasGAP PF00616.19 KFP11453.1 - 0.0099 15.6 0.8 0.096 12.4 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Rad60-SLD_2 PF13881.6 KFP11453.1 - 0.014 15.5 0.2 0.029 14.5 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SpoIIIAH PF12685.7 KFP11453.1 - 0.028 14.2 1.1 1.6 8.5 0.1 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein CUE PF02845.16 KFP11453.1 - 0.07 12.8 1.5 0.23 11.2 0.0 2.6 2 0 0 2 2 2 0 CUE domain HOIP-UBA PF16678.5 KFP11453.1 - 0.13 12.2 0.7 0.29 11.1 0.2 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair DUF2407 PF10302.9 KFP11453.1 - 0.15 12.6 0.1 0.67 10.5 0.1 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Clathrin-link PF09268.10 KFP11453.1 - 1.8 8.0 15.9 6.5 6.2 0.1 5.2 5 0 0 5 5 5 0 Clathrin, heavy-chain linker Herpes_pp85 PF04637.12 KFP11453.1 - 9.3 4.5 10.2 0.34 9.3 1.8 2.1 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Kinesin PF00225.23 KFP11454.1 - 3e-109 365.0 3.0 3e-109 365.0 3.0 3.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP11454.1 - 5.7e-24 84.7 3.5 6.8e-24 84.5 0.0 3.1 2 0 0 2 2 2 1 Microtubule binding Tropomyosin_1 PF12718.7 KFP11454.1 - 0.0063 16.7 3.2 0.0063 16.7 3.2 8.4 5 1 3 8 8 8 1 Tropomyosin like Pox_A_type_inc PF04508.12 KFP11454.1 - 0.036 13.9 7.8 0.069 13.0 1.6 4.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Q_salvage PF10343.9 KFP11455.1 - 1.1e-90 304.1 0.1 1.2e-90 303.9 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family RMI1_N PF08585.12 KFP11456.1 - 3.4e-56 190.4 0.1 6.2e-56 189.6 0.1 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein RMI1_C PF16099.5 KFP11456.1 - 8.2e-46 155.4 0.0 2.2e-45 154.0 0.0 1.8 2 0 0 2 2 2 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Nucleos_tra2_C PF07662.13 KFP11458.1 - 8.8e-77 257.6 5.0 8.8e-77 257.6 5.0 2.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFP11458.1 - 8.8e-23 80.7 3.1 8.8e-23 80.7 3.1 4.1 5 1 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KFP11458.1 - 8.1e-08 32.5 7.3 8.1e-08 32.5 7.3 3.7 4 0 0 4 4 4 1 Nucleoside recognition S_4TM PF18159.1 KFP11458.1 - 6.6 5.9 7.2 11 5.2 1.8 2.5 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Pkinase_Tyr PF07714.17 KFP11460.1 - 1e-96 323.2 0.0 1.4e-96 322.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11460.1 - 1.9e-48 165.1 0.0 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFP11460.1 - 9.1e-23 80.2 0.1 1.5e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP11460.1 - 1.7e-16 60.6 4.5 1.1e-10 41.9 1.5 2.6 2 0 0 2 2 2 2 Immunoglobulin domain TPKR_C2 PF16920.5 KFP11460.1 - 1.9e-13 50.3 1.0 5.1e-13 48.9 0.4 2.1 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain ig PF00047.25 KFP11460.1 - 1.7e-11 44.1 0.4 1.1e-07 31.9 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP11460.1 - 1.9e-11 44.1 2.9 4.6e-08 33.3 0.5 2.7 2 0 0 2 2 2 2 Immunoglobulin domain LRR_8 PF13855.6 KFP11460.1 - 4.3e-09 36.0 2.2 1.2e-08 34.6 2.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat Ig_C17orf99 PF17736.1 KFP11460.1 - 0.0013 18.7 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 C17orf99 Ig domain V-set PF07686.17 KFP11460.1 - 0.0026 17.9 0.4 1.6 9.0 0.0 3.2 1 1 2 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP11460.1 - 0.0036 17.3 0.3 2 8.6 0.1 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain TMEM154 PF15102.6 KFP11460.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Haspin_kinase PF12330.8 KFP11460.1 - 0.034 13.1 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LRR_1 PF00560.33 KFP11460.1 - 0.23 12.1 1.5 1.4 9.8 1.5 2.4 1 0 0 1 1 1 0 Leucine Rich Repeat LRR_4 PF12799.7 KFP11460.1 - 9.6 6.8 8.9 1.2 9.6 1.6 3.1 2 1 1 3 3 2 0 Leucine Rich repeats (2 copies) TLE_N PF03920.15 KFP11461.1 - 0.92 9.6 11.9 0.19 11.8 7.8 2.0 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain SpecificRecomb PF10136.9 KFP11461.1 - 7.3 4.8 8.7 2.7 6.2 2.8 2.2 1 1 1 2 2 2 0 Site-specific recombinase Helicase_IV_N PF12462.8 KFP11461.1 - 8.6 6.3 11.8 2.4 8.1 2.5 2.3 1 1 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Fe-S_biosyn PF01521.20 KFP11462.1 - 8.4e-19 67.8 0.0 9.3e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TUTF7_u4 PF16631.5 KFP11463.1 - 6.3e-37 126.1 24.5 6.3e-37 126.1 24.5 3.1 4 0 0 4 4 1 1 Unstructured region 4 on terminal uridylyltransferase 7 PAP_assoc PF03828.19 KFP11463.1 - 3.8e-27 94.3 0.1 2.2e-14 53.4 0.2 3.1 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFP11463.1 - 5.5e-13 48.3 24.3 3.3e-05 23.7 2.3 4.1 4 0 0 4 4 4 3 Zinc knuckle NTP_transf_2 PF01909.23 KFP11463.1 - 1.7e-05 25.0 0.0 0.00014 22.1 0.0 2.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_2 PF13696.6 KFP11463.1 - 0.00014 21.6 33.4 0.011 15.5 5.7 4.9 5 0 0 5 5 5 3 Zinc knuckle tRNA_NucTransf2 PF09249.11 KFP11463.1 - 0.0003 21.0 0.0 1.3 9.3 0.0 2.9 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain zf-CCHC_4 PF14392.6 KFP11463.1 - 0.00087 19.0 13.3 0.23 11.2 0.3 3.7 3 0 0 3 3 3 2 Zinc knuckle Polbeta PF18765.1 KFP11463.1 - 0.0039 17.2 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Spt46 PF17734.1 KFP11463.1 - 0.017 15.0 0.2 0.5 10.1 0.0 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 zf-C2H2_jaz PF12171.8 KFP11463.1 - 0.037 14.3 3.2 0.14 12.5 3.2 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP11463.1 - 0.049 14.0 4.9 0.081 13.3 0.8 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KFP11463.1 - 2.5 8.3 5.7 12 6.1 0.1 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CCHC_5 PF14787.6 KFP11463.1 - 6.6 6.5 18.7 3.6 7.4 0.2 3.8 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger SSB PF00436.25 KFP11464.1 - 1.1e-31 109.0 0.4 1.3e-31 108.7 0.4 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Pkinase PF00069.25 KFP11465.1 - 2.8e-53 181.0 0.0 3.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11465.1 - 3.1e-23 82.4 0.0 5e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2347 PF09804.9 KFP11466.1 - 1.5e-72 244.6 0.0 1.9e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KFP11466.1 - 1.8e-13 50.4 0.0 3.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFP11466.1 - 2.4e-09 36.4 1.8 0.00036 19.4 0.1 3.2 2 1 0 2 2 2 2 Transport protein Avl9 Baculo_LEF-11 PF06385.12 KFP11466.1 - 0.065 13.7 0.8 0.12 12.8 0.8 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein DAGK_cat PF00781.24 KFP11467.1 - 1.6e-19 69.7 0.2 6.8e-19 67.7 0.2 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KFP11467.1 - 0.00027 20.2 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase GATase PF00117.28 KFP11467.1 - 0.052 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Claudin_2 PF13903.6 KFP11468.1 - 1.6e-10 41.0 5.4 2e-10 40.7 5.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP11468.1 - 0.00016 21.6 4.5 0.00025 21.0 4.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family RVT_1 PF00078.27 KFP11469.1 - 0.013 15.1 0.0 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) MRP-S33 PF08293.11 KFP11470.1 - 5.5e-26 90.6 3.4 7e-26 90.3 3.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Pkinase_Tyr PF07714.17 KFP11472.1 - 1.5e-63 214.5 0.0 2.2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11472.1 - 1e-58 198.8 0.0 1.4e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KFP11472.1 - 1.5e-26 92.2 0.0 3.6e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFP11472.1 - 3.3e-12 46.1 7.1 6.4e-12 45.2 7.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP11472.1 - 1.1e-08 34.7 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.11 KFP11472.1 - 7.8e-05 22.9 2.7 0.00021 21.5 2.7 1.7 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFP11472.1 - 0.0031 17.8 3.6 0.007 16.7 3.6 1.6 1 0 0 1 1 1 1 C1 domain Pkinase_fungal PF17667.1 KFP11472.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP11472.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP11472.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DENN PF02141.21 KFP11473.1 - 4.8e-57 192.9 1.1 1e-56 191.9 1.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP11473.1 - 4.8e-16 59.3 0.2 1e-15 58.2 0.2 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP11473.1 - 9e-12 44.8 0.7 2.7e-11 43.3 0.7 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 KFP11473.1 - 0.19 11.7 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Uds1 PF15456.6 KFP11473.1 - 9.2 6.4 11.4 10 6.3 1.0 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Indigoidine_A PF04227.12 KFP11474.1 - 5.3e-133 442.8 1.9 1.2e-132 441.7 1.7 1.6 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 KFP11474.1 - 1.7e-19 70.3 0.0 3.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPP_enzyme_N PF02776.18 KFP11474.1 - 0.11 12.1 0.2 1.2 8.8 0.0 2.8 3 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MKRN1_C PF15815.5 KFP11475.1 - 3e-33 114.1 3.9 8.4e-33 112.6 3.9 1.7 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-CCCH_4 PF18044.1 KFP11475.1 - 1e-27 95.4 40.4 8.6e-08 31.8 8.1 4.7 4 0 0 4 4 4 4 CCCH-type zinc finger Torus PF16131.5 KFP11475.1 - 3.9e-17 62.9 16.5 2.4e-06 28.2 1.3 4.4 3 1 1 4 4 4 4 Torus domain zf-CCCH PF00642.24 KFP11475.1 - 5.4e-15 54.9 35.6 1.4e-05 24.8 0.1 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP11475.1 - 5.9e-14 51.6 41.7 2.3e-05 24.3 2.4 5.0 4 1 0 4 4 4 3 Zinc finger domain zf-C3HC4 PF00097.25 KFP11475.1 - 6.6e-07 29.1 7.1 6.6e-07 29.1 7.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP11475.1 - 8.7e-06 25.7 3.0 2.5e-05 24.2 3.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP11475.1 - 3.5e-05 23.7 6.1 3.5e-05 23.7 6.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP11475.1 - 6e-05 23.3 6.2 6e-05 23.3 6.2 3.0 4 1 0 4 4 1 1 Ring finger domain zf-CCCH_3 PF15663.5 KFP11475.1 - 0.00017 21.8 5.8 0.00017 21.8 5.8 3.2 3 1 0 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFP11475.1 - 0.0002 21.7 30.9 0.93 10.1 1.3 5.0 4 1 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 KFP11475.1 - 0.00098 19.4 5.0 0.00098 19.4 5.0 3.1 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP11475.1 - 0.0011 19.0 3.7 0.0011 19.0 3.7 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFP11475.1 - 0.0036 17.4 4.0 0.0036 17.4 4.0 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFP11475.1 - 0.013 15.2 2.4 0.055 13.2 2.4 2.2 1 0 0 1 1 1 0 RING-like zinc finger DUF4929 PF16283.5 KFP11475.1 - 0.21 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) zf-C3HC4_2 PF13923.6 KFP11475.1 - 0.57 10.1 15.7 0.51 10.2 10.1 3.7 3 1 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KFP11475.1 - 3.4 7.9 10.6 2.1 8.6 5.9 2.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 Ras PF00071.22 KFP11476.1 - 9.6e-56 187.9 0.7 1.1e-55 187.7 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11476.1 - 4.5e-36 123.7 0.4 6.8e-36 123.1 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11476.1 - 4.1e-15 55.7 0.1 5.1e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP11476.1 - 1.7e-05 24.4 0.7 7.4e-05 22.4 0.7 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP11476.1 - 3.8e-05 23.7 0.1 5.7e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP11476.1 - 0.00023 20.6 0.2 0.00031 20.2 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP11476.1 - 0.00038 19.9 0.1 0.00064 19.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFP11476.1 - 0.0011 18.5 0.6 0.058 12.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 KFP11476.1 - 0.0019 17.7 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial TniB protein PduV-EutP PF10662.9 KFP11476.1 - 0.013 15.3 0.6 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFP11476.1 - 0.043 13.5 0.0 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFP11476.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Septin MFS_1 PF07690.16 KFP11477.1 - 9.6e-40 136.6 28.7 2.3e-36 125.4 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP11477.1 - 7.6e-05 21.7 31.8 0.0036 16.2 10.1 3.1 2 2 0 2 2 2 2 Sugar (and other) transporter Gly-zipper_YMGG PF13441.6 KFP11477.1 - 3.6 7.4 0.0 3.6 7.4 0.0 3.5 4 1 0 4 4 4 0 YMGG-like Gly-zipper JHD PF17811.1 KFP11478.1 - 4.5e-43 146.0 0.0 1.3e-42 144.5 0.0 1.9 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KFP11478.1 - 2.9e-11 43.8 2.1 5.6e-10 39.7 2.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFP11478.1 - 2.4e-08 34.0 0.3 2.4e-08 34.0 0.3 2.9 2 2 0 2 2 2 1 Cupin-like domain AA_permease_2 PF13520.6 KFP11479.1 - 4e-51 174.2 35.0 4.7e-51 174.0 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP11479.1 - 3.1e-25 88.7 32.3 7.6e-25 87.4 32.4 1.6 1 1 0 1 1 1 1 Amino acid permease FUSC-like PF12805.7 KFP11479.1 - 0.14 11.2 0.1 0.14 11.2 0.1 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS PARP PF00644.20 KFP11480.1 - 2.6e-40 138.1 0.5 3.6e-39 134.4 0.5 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain HJURP_C PF12347.8 KFP11480.1 - 0.015 15.3 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Bromodomain PF00439.25 KFP11481.1 - 1e-23 83.2 0.2 2.8e-23 81.8 0.2 1.8 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.24 KFP11481.1 - 2.7e-11 43.4 22.5 1.9e-09 37.5 7.7 4.7 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.29 KFP11481.1 - 3.2e-08 33.3 10.1 3.2e-08 33.3 10.1 4.5 4 1 0 4 4 4 1 PHD-finger MFS_1 PF07690.16 KFP11482.1 - 2e-28 99.3 47.2 6.9e-22 77.8 23.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP11482.1 - 9e-23 80.8 33.6 6.3e-19 68.2 10.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter V_ATPase_I PF01496.19 KFP11483.1 - 0 1111.9 4.6 0 1111.7 4.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.11 KFP11483.1 - 0.23 11.3 2.6 0.38 10.6 1.7 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PspA_IM30 PF04012.12 KFP11483.1 - 0.25 10.9 1.9 0.89 9.1 0.0 2.1 2 0 0 2 2 2 0 PspA/IM30 family TMEM213 PF15192.6 KFP11484.1 - 3.3e-32 110.3 1.2 3.5e-32 110.2 1.2 1.0 1 0 0 1 1 1 1 TMEM213 family p450 PF00067.22 KFP11487.1 - 7.7e-92 308.4 1.0 6.3e-72 242.8 0.2 2.0 2 0 0 2 2 2 2 Cytochrome P450 PARP PF00644.20 KFP11488.1 - 8.6e-39 133.1 2.2 2.8e-38 131.5 2.2 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ets PF00178.22 KFP11489.1 - 4.2e-23 81.6 0.4 7.2e-23 80.9 0.4 1.4 1 0 0 1 1 1 1 Ets-domain I-set PF07679.16 KFP11490.1 - 2.4e-95 312.8 3.8 7.4e-20 70.8 0.0 7.7 8 0 0 8 8 8 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP11490.1 - 5.9e-62 206.2 1.3 1.8e-14 54.0 0.1 7.6 7 0 0 7 7 7 7 Immunoglobulin domain fn3 PF00041.21 KFP11490.1 - 1.6e-43 146.9 0.1 1.5e-13 50.9 0.0 4.8 4 0 0 4 4 4 3 Fibronectin type III domain Ig_2 PF13895.6 KFP11490.1 - 1.7e-40 137.2 0.9 1.4e-09 38.1 0.1 7.6 7 1 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFP11490.1 - 2.5e-36 123.7 2.8 4.1e-10 39.7 0.0 7.6 8 0 0 8 8 8 6 Immunoglobulin domain THB PF18362.1 KFP11490.1 - 2.3e-21 75.1 0.4 9.4e-21 73.1 0.0 2.1 2 0 0 2 2 2 1 Tri-helix bundle domain V-set PF07686.17 KFP11490.1 - 1.6e-17 63.6 6.2 0.023 14.9 0.1 9.5 7 3 0 7 7 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP11490.1 - 5.2e-11 42.5 0.3 0.049 13.7 0.0 6.0 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP11490.1 - 3.2e-07 30.7 2.6 1.3 9.5 0.1 6.2 7 0 0 7 7 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFP11490.1 - 7.8e-06 26.2 9.2 0.83 10.1 0.0 6.4 7 0 0 7 7 7 1 Immunoglobulin C1-set domain DUF4251 PF14059.6 KFP11490.1 - 0.0069 16.3 2.3 6.6 6.7 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4251) Ig_4 PF16680.5 KFP11490.1 - 0.018 15.3 12.2 0.41 10.9 0.1 5.5 6 1 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain LIFR_D2 PF17971.1 KFP11490.1 - 0.042 14.0 0.2 0.42 10.8 0.0 2.6 3 0 0 3 3 2 0 Leukemia inhibitory factor receptor D2 domain V-set_CD47 PF08204.11 KFP11490.1 - 0.076 13.0 0.8 14 5.7 0.0 3.5 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain fn3_2 PF16893.5 KFP11490.1 - 0.1 12.8 0.0 23 5.2 0.0 2.9 2 0 0 2 2 2 0 Fibronectin type III domain CDP-OH_P_transf PF01066.21 KFP11491.1 - 7.5e-12 45.8 5.7 1.3e-11 45.1 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Methyltransf_9 PF08003.11 KFP11491.1 - 0.2 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PspC PF04024.12 KFP11491.1 - 3.2 7.6 7.3 19 5.2 1.5 3.7 3 1 0 3 3 3 0 PspC domain Stealth_CR2 PF11380.8 KFP11492.1 - 7.8e-46 154.7 2.4 2.2e-45 153.3 0.4 2.6 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 GlcNAc-1_reg PF18440.1 KFP11492.1 - 1.5e-44 150.1 0.1 5.2e-44 148.4 0.1 2.0 1 0 0 1 1 1 1 Putative GlcNAc-1 phosphotransferase regulatory domain Stealth_CR4 PF17103.5 KFP11492.1 - 3.7e-24 84.4 3.0 9e-24 83.1 1.7 2.2 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 KFP11492.1 - 7.4e-19 67.4 7.0 1.9e-18 66.1 7.0 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 KFP11492.1 - 1.6e-15 57.2 31.9 5.1e-09 36.4 12.6 2.4 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 KFP11492.1 - 8.3e-12 44.6 0.0 1.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DMAP_binding PF06464.11 KFP11492.1 - 2.4e-11 44.4 0.3 6.6e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain EF-hand_1 PF00036.32 KFP11492.1 - 0.025 14.1 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KFP11492.1 - 0.12 12.9 0.1 0.82 10.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFP11492.1 - 0.15 11.6 0.1 0.42 10.2 0.1 1.8 1 0 0 1 1 1 0 EF hand Frag1 PF10277.9 KFP11494.1 - 2e-39 135.4 15.6 2.3e-39 135.2 15.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CCDC53 PF10152.9 KFP11495.1 - 2e-49 167.9 0.3 2.5e-49 167.6 0.3 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex WD40 PF00400.32 KFP11496.1 - 2e-14 53.7 0.9 7.8e-05 23.4 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11496.1 - 0.00047 20.4 0.0 0.0069 16.7 0.0 2.7 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4178 PF13785.6 KFP11496.1 - 0.13 12.4 0.4 1.4 9.0 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4178) UvrD_C PF13361.6 KFP11497.1 - 0.0039 16.6 0.1 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Pro-MCH PF05824.12 KFP11498.1 - 1.5e-48 162.6 0.0 2.3e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) Insulin PF00049.18 KFP11499.1 - 4.9e-15 56.3 5.9 2.6e-12 47.6 5.9 2.2 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFP11499.1 - 0.12 12.4 2.0 5.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Biopterin_H PF00351.21 KFP11500.1 - 3.1e-172 572.1 0.9 3.8e-172 571.8 0.9 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase YfdX PF10938.8 KFP11500.1 - 0.091 12.7 0.3 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 YfdX protein Biopterin_H PF00351.21 KFP11501.1 - 5e-177 587.9 0.0 6.8e-177 587.4 0.0 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFP11501.1 - 5.7e-10 38.8 0.0 1.2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KFP11501.1 - 0.00024 21.6 0.1 0.0011 19.6 0.0 1.9 2 0 0 2 2 2 1 ACT domain Rep_4 PF05797.11 KFP11502.1 - 0.044 12.9 0.1 0.044 12.9 0.1 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) NOA36 PF06524.12 KFP11502.1 - 0.12 11.7 3.9 0.12 11.6 3.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KFP11502.1 - 1.1 7.2 8.3 1.2 7.1 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_Tyr PF07714.17 KFP11503.1 - 1.8e-93 312.6 0.0 2.8e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.13 KFP11503.1 - 5.7e-56 188.2 3.2 1.4e-55 186.9 3.2 1.7 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.25 KFP11503.1 - 6.5e-46 156.8 0.0 1.6e-45 155.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain FERM_N_2 PF18038.1 KFP11503.1 - 4.7e-44 149.2 0.2 1.4e-43 147.6 0.2 1.9 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KFP11503.1 - 1.8e-11 44.5 0.1 1.8e-11 44.5 0.1 2.4 3 0 0 3 3 3 1 FERM central domain Haspin_kinase PF12330.8 KFP11503.1 - 0.0013 17.8 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP11503.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FERM_F2 PF18377.1 KFP11503.1 - 0.019 14.9 0.3 0.052 13.5 0.3 1.8 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain uDENN PF03456.18 KFP11504.1 - 2.5e-06 28.1 0.0 6.3e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 uDENN domain DENN PF02141.21 KFP11504.1 - 0.044 13.7 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 DENN (AEX-3) domain dDENN PF03455.19 KFP11505.1 - 2.4e-06 27.4 0.7 6.8e-06 26.0 0.7 1.8 1 0 0 1 1 1 1 dDENN domain bPH_3 PF14470.6 KFP11505.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain MFS_1 PF07690.16 KFP11506.1 - 4.9e-17 61.9 12.0 8.1e-11 41.4 0.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KFP11506.1 - 2.2e-08 33.1 1.0 2.2e-08 33.1 1.0 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.20 KFP11506.1 - 0.012 13.9 4.9 0.25 9.6 0.1 3.0 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family 7tm_1 PF00001.21 KFP11507.1 - 4.3e-30 104.9 36.4 7e-30 104.2 36.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5412 PF17428.2 KFP11507.1 - 0.041 13.7 0.1 0.041 13.7 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5412) DNA_methylase PF00145.17 KFP11510.1 - 1e-37 130.3 0.0 1.5e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Filament PF00038.21 KFP11511.1 - 4.8e-78 262.9 29.1 5.7e-78 262.6 29.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 KFP11511.1 - 0.00084 19.4 1.3 0.00084 19.4 1.3 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KFP11511.1 - 0.00091 19.6 26.4 0.0061 16.9 16.4 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4200) Phage_GP20 PF06810.11 KFP11511.1 - 0.0032 17.3 5.2 0.0032 17.3 5.2 3.0 2 1 0 3 3 2 1 Phage minor structural protein GP20 DUF1759 PF03564.15 KFP11511.1 - 0.0061 16.5 7.1 0.41 10.6 0.6 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF1759) TolA_bind_tri PF16331.5 KFP11511.1 - 0.014 15.4 3.9 0.014 15.4 3.9 4.4 2 1 2 4 4 4 0 TolA binding protein trimerisation EspB PF05802.11 KFP11511.1 - 0.021 14.8 8.1 0.034 14.1 6.4 1.9 1 1 1 2 2 2 0 Enterobacterial EspB protein HGTP_anticodon PF03129.20 KFP11511.1 - 0.024 14.8 3.1 2.5 8.3 0.1 2.8 2 0 0 2 2 2 0 Anticodon binding domain DUF4515 PF14988.6 KFP11511.1 - 0.026 14.4 25.6 0.016 15.0 12.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) HMMR_N PF15905.5 KFP11511.1 - 0.037 13.5 20.5 0.47 9.9 20.5 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 KFP11511.1 - 0.047 12.6 25.0 0.33 9.8 14.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein MdcG PF10620.9 KFP11511.1 - 0.052 13.3 2.3 0.089 12.6 0.4 2.1 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG BRE1 PF08647.11 KFP11511.1 - 0.056 13.5 25.0 1.5 8.9 7.6 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF5082 PF16888.5 KFP11511.1 - 0.071 13.4 16.7 0.29 11.4 0.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4795 PF16043.5 KFP11511.1 - 0.089 12.4 20.6 0.022 14.4 9.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) RBD-FIP PF09457.10 KFP11511.1 - 0.11 12.5 0.6 0.11 12.5 0.6 2.4 2 0 0 2 2 1 0 FIP domain Baculo_PEP_C PF04513.12 KFP11511.1 - 0.11 12.5 6.7 0.33 11.0 2.5 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KFP11511.1 - 0.19 12.1 18.0 0.046 14.0 4.1 3.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KFP11511.1 - 0.2 11.9 4.6 19 5.6 0.1 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 KFP11511.1 - 0.3 11.4 21.5 0.54 10.6 5.9 4.3 1 1 2 3 3 3 0 Tup N-terminal Prefoldin PF02996.17 KFP11511.1 - 0.32 10.9 19.4 0.069 13.1 2.4 4.2 2 1 2 4 4 4 0 Prefoldin subunit HALZ PF02183.18 KFP11511.1 - 0.34 11.2 0.1 0.34 11.2 0.1 5.1 6 1 0 6 6 3 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 KFP11511.1 - 0.35 10.9 22.5 0.034 14.2 9.0 2.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 KFP11511.1 - 0.38 10.5 24.8 1.1 9.0 3.1 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF600 PF04634.12 KFP11511.1 - 0.42 10.7 3.7 0.28 11.2 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function, DUF600 Prominin PF05478.11 KFP11511.1 - 0.46 8.4 10.7 0.64 7.9 10.7 1.2 1 0 0 1 1 1 0 Prominin DUF4404 PF14357.6 KFP11511.1 - 0.51 11.0 12.8 0.56 10.9 2.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) T2SSF PF00482.23 KFP11511.1 - 0.53 10.3 4.1 0.58 10.1 2.4 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F CLZ PF16526.5 KFP11511.1 - 0.55 10.6 15.8 0.3 11.5 1.9 3.8 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 KFP11511.1 - 0.56 10.0 16.7 1.5 8.6 8.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.8 KFP11511.1 - 0.57 10.4 23.1 0.49 10.6 8.6 3.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding ApoLp-III PF07464.11 KFP11511.1 - 0.57 10.3 13.4 5 7.2 0.3 2.9 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 KFP11511.1 - 0.6 9.5 24.9 0.65 9.4 12.0 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 AAA_13 PF13166.6 KFP11511.1 - 0.66 8.6 15.9 0.88 8.1 15.9 1.2 1 0 0 1 1 1 0 AAA domain PI3K_P85_iSH2 PF16454.5 KFP11511.1 - 0.85 9.2 21.2 1.6 8.3 3.9 3.1 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3450 PF11932.8 KFP11511.1 - 0.89 8.8 26.1 0.92 8.8 1.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) LPP PF04728.13 KFP11511.1 - 1 9.8 16.1 1.5 9.3 1.4 4.8 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Jnk-SapK_ap_N PF09744.9 KFP11511.1 - 1.1 9.5 24.2 0.5 10.6 13.4 3.0 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_CLD_2 PF14197.6 KFP11511.1 - 1.1 9.4 19.2 3.4 7.8 5.6 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 KFP11511.1 - 1.2 9.2 28.7 0.22 11.6 17.5 3.3 1 1 2 3 3 2 0 TPR/MLP1/MLP2-like protein DUF4085 PF13315.6 KFP11511.1 - 1.2 8.7 11.8 1.5 8.4 0.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) ACCA PF03255.14 KFP11511.1 - 1.2 9.0 16.0 0.19 11.6 1.2 3.1 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit WXG100 PF06013.12 KFP11511.1 - 1.3 9.3 13.8 5.5 7.3 0.3 3.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG PRKG1_interact PF15898.5 KFP11511.1 - 1.3 10.0 20.5 0.079 13.9 9.0 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 KFP11511.1 - 1.3 9.2 15.8 1.8 8.7 1.8 4.0 2 1 2 4 4 3 0 bZIP transcription factor CENP-H PF05837.12 KFP11511.1 - 1.3 9.4 20.8 4.9 7.6 8.3 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF5344 PF17279.2 KFP11511.1 - 1.3 9.6 11.9 2 9.0 2.1 3.4 2 2 1 3 3 3 0 Family of unknown function (DUF5344) KASH_CCD PF14662.6 KFP11511.1 - 1.4 8.7 26.6 0.55 10.0 8.5 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 KFP11511.1 - 2.4 7.1 15.3 4.1 6.4 15.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC92 PF14916.6 KFP11511.1 - 2.5 7.9 10.6 2.3 8.0 5.3 3.3 2 2 1 3 3 3 0 Coiled-coil domain of unknown function Phlebovirus_NSM PF07246.11 KFP11511.1 - 2.6 7.4 12.5 0.94 8.8 1.0 2.2 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 KFP11511.1 - 2.8 7.2 18.0 3 7.1 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) KLRAQ PF10205.9 KFP11511.1 - 3.3 8.0 22.3 5.7 7.2 1.3 4.4 2 1 2 4 4 4 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 KFP11511.1 - 4 7.9 11.1 4.8 7.7 0.4 4.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 KFP11511.1 - 4.3 7.6 20.1 3.5 7.9 1.8 4.4 1 1 4 5 5 5 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 KFP11511.1 - 5.2 6.2 14.5 0.75 9.0 8.0 2.3 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 KFP11511.1 - 5.5 7.5 30.6 0.13 12.8 6.8 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 KFP11511.1 - 5.5 7.0 26.6 1.1 9.3 13.5 3.0 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Phage_Mu_Gam PF07352.12 KFP11511.1 - 5.6 6.8 22.0 4.3 7.2 3.5 3.4 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.10 KFP11511.1 - 6 7.1 17.1 2.7 8.2 6.7 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3391 PF11871.8 KFP11511.1 - 6.6 7.3 11.4 0.88 10.1 6.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Rho_Binding PF08912.11 KFP11511.1 - 7.4 7.5 24.8 4.4 8.2 2.4 4.7 1 1 4 5 5 5 0 Rho Binding BST2 PF16716.5 KFP11511.1 - 8.4 7.1 19.5 10 6.8 1.0 3.5 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Glyco_transf_29 PF00777.18 KFP11512.1 - 9.1e-81 271.2 0.0 1.4e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PTPLA PF04387.14 KFP11514.1 - 4e-59 199.0 13.4 4.7e-59 198.8 13.4 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA VHS PF00790.19 KFP11515.1 - 2.2e-44 150.8 1.4 3.5e-44 150.1 0.1 2.0 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KFP11515.1 - 4.2e-16 58.3 0.1 7.9e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP11515.1 - 1.7e-12 46.9 0.0 2.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP11515.1 - 1.6e-11 43.8 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KFP11515.1 - 7.6e-05 22.4 1.7 0.0002 21.1 1.7 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif GAT PF03127.14 KFP11515.1 - 0.014 15.7 3.4 0.036 14.4 3.4 1.8 1 0 0 1 1 1 0 GAT domain SH3_10 PF17902.1 KFP11515.1 - 0.039 14.0 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 SH3 domain HEAT PF02985.22 KFP11515.1 - 0.45 10.9 1.5 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.21 KFP11516.1 - 1.1e-75 251.3 8.8 1.3e-24 87.0 0.2 4.9 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.19 KFP11516.1 - 9.3e-15 54.6 12.9 1.2e-14 54.3 10.5 2.5 2 0 0 2 2 2 1 Fibronectin type II domain Ricin_B_lectin PF00652.22 KFP11516.1 - 9.3e-09 35.6 0.2 2.1e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain UL45 PF05473.12 KFP11516.1 - 3.8e-08 33.2 0.2 1.1e-05 25.2 0.0 3.3 3 0 0 3 3 3 1 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFP11516.1 - 2.2e-06 27.9 3.0 0.37 11.2 0.3 5.0 4 1 0 4 4 4 2 Extracellular link domain Chordopox_A33R PF05966.12 KFP11516.1 - 0.00067 19.0 0.6 0.036 13.3 0.1 2.9 3 0 0 3 3 3 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 KFP11517.1 - 5.5e-81 268.4 14.5 1.5e-26 93.2 0.7 5.0 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.19 KFP11517.1 - 3.1e-17 62.5 7.6 3.1e-17 62.5 7.6 2.7 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFP11517.1 - 1.9e-13 50.6 2.7 3.9e-06 26.7 0.0 3.9 3 1 1 4 4 4 3 UL45 protein, carbohydrate-binding C-type lectin-like Ricin_B_lectin PF00652.22 KFP11517.1 - 3.5e-09 37.0 1.0 3.5e-09 37.0 1.0 2.7 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Xlink PF00193.17 KFP11517.1 - 2.1e-07 31.2 7.0 0.32 11.4 0.2 5.9 5 1 1 6 6 6 3 Extracellular link domain Chordopox_A33R PF05966.12 KFP11517.1 - 9.6e-05 21.7 6.5 0.57 9.4 0.0 3.9 5 0 0 5 5 5 3 Chordopoxvirus A33R protein Adeno_E3_CR1 PF02440.15 KFP11517.1 - 0.3 10.9 6.4 0.34 10.7 0.4 3.7 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Lectin_C PF00059.21 KFP11518.1 - 1.3e-18 67.7 0.9 2e-18 67.1 0.9 1.3 1 0 0 1 1 1 1 Lectin C-type domain DUF4271 PF14093.6 KFP11518.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF4366 PF14283.6 KFP11518.1 - 0.014 15.4 0.1 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) 7tm_2 PF00002.24 KFP11518.1 - 0.034 13.4 0.1 0.049 12.9 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Orf78 PF06024.12 KFP11518.1 - 0.091 13.1 0.3 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 Orf78 (ac78) LapA_dom PF06305.11 KFP11518.1 - 0.1 12.4 0.5 0.18 11.6 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Lectin_C PF00059.21 KFP11519.1 - 8.9e-158 515.4 57.4 1.3e-24 87.0 0.0 9.2 9 1 1 10 10 10 8 Lectin C-type domain fn2 PF00040.19 KFP11519.1 - 2.2e-16 59.8 1.7 1.1e-15 57.6 1.7 2.4 1 0 0 1 1 1 1 Fibronectin type II domain UL45 PF05473.12 KFP11519.1 - 3.7e-14 52.8 11.3 0.0022 17.7 0.0 7.8 6 2 2 8 8 8 4 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFP11519.1 - 6.8e-10 39.2 9.3 0.22 11.9 0.2 8.9 8 0 0 8 8 8 2 Extracellular link domain Ricin_B_lectin PF00652.22 KFP11519.1 - 1.8e-08 34.7 1.3 1.8e-08 34.7 1.3 2.6 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.12 KFP11519.1 - 0.012 14.9 8.0 9.2 5.5 0.0 6.0 7 0 0 7 7 7 0 Chordopoxvirus A33R protein Intimin_C PF07979.11 KFP11519.1 - 0.021 15.3 14.7 26 5.3 0.0 8.0 9 0 0 9 9 9 0 Intimin C-type lectin domain CdiI_N PF18228.1 KFP11519.1 - 0.049 13.5 0.1 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 CdiI N-terminal domain DUF3301 PF11743.8 KFP11519.1 - 0.53 10.0 3.0 6.9 6.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3301) DUF1737 PF08410.10 KFP11519.1 - 6.7 6.7 5.7 1.1e+02 2.8 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1737) Guanylate_kin PF00625.21 KFP11523.1 - 3.2e-50 170.3 0.2 6.8e-50 169.3 0.2 1.6 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFP11523.1 - 5.3e-23 80.8 6.6 5.3e-23 80.8 6.6 2.9 3 0 0 3 3 3 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFP11523.1 - 0.0017 17.9 0.1 0.0064 16.1 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP11523.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Methyltr_RsmB-F PF01189.17 KFP11524.1 - 6.3e-46 156.5 0.0 9.8e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KFP11524.1 - 1.7e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFP11524.1 - 3.7e-07 30.4 0.0 7.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2431 PF10354.9 KFP11524.1 - 0.0011 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PCMT PF01135.19 KFP11524.1 - 0.002 17.9 0.1 0.0046 16.7 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PUA PF01472.20 KFP11524.1 - 0.0042 17.0 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 PUA domain Methyltransf_15 PF09445.10 KFP11524.1 - 0.005 16.4 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KFP11524.1 - 0.018 15.7 0.0 0.055 14.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFP11524.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Arf PF00025.21 KFP11525.1 - 4.4e-65 218.4 0.2 4.8e-65 218.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP11525.1 - 7.4e-16 58.4 0.1 9.7e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP11525.1 - 3.2e-14 52.8 0.1 3.6e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP11525.1 - 6.8e-13 48.4 0.1 9.2e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP11525.1 - 5.1e-09 35.8 0.4 3e-06 26.7 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP11525.1 - 2.9e-07 30.6 0.1 4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP11525.1 - 3.6e-07 29.8 0.2 4.2e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP11525.1 - 0.0019 17.8 0.1 0.027 14.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFP11525.1 - 0.013 15.5 0.1 0.038 14.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 KFP11525.1 - 0.085 12.4 0.6 0.35 10.4 0.5 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B Peptidase_M10 PF00413.24 KFP11526.1 - 1.4e-62 210.3 0.2 2.7e-62 209.3 0.2 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP11526.1 - 2e-54 181.3 20.2 9.1e-16 57.5 0.9 4.5 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.8 KFP11526.1 - 2.6e-29 101.0 1.8 4.1e-29 100.3 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.18 KFP11526.1 - 3.6e-11 43.1 0.1 7.4e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP11526.1 - 0.0002 21.0 1.4 0.43 10.2 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4293 PF14126.6 KFP11526.1 - 0.0027 17.9 0.1 0.0048 17.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) Peptidase_M66 PF10462.9 KFP11526.1 - 0.04 12.9 0.4 0.066 12.2 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 KFP11526.1 - 0.048 12.3 0.1 0.071 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 KFP11526.1 - 0.058 13.9 0.2 0.18 12.3 0.3 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFP11526.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KFP11526.1 - 0.093 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_4 PF13583.6 KFP11526.1 - 0.26 10.9 0.1 0.49 10.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like eIF-6 PF01912.18 KFP11527.1 - 7.8e-50 169.0 0.0 1.4e-49 168.1 0.0 1.3 2 0 0 2 2 2 1 eIF-6 family FAM83 PF07894.12 KFP11528.1 - 2.1e-101 339.1 0.2 4.9e-101 337.9 0.0 1.7 2 1 1 3 3 3 1 FAM83 A-H PLDc_2 PF13091.6 KFP11528.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 1 0 1 1 1 1 PLD-like domain SPACA9 PF15120.6 KFP11528.1 - 0.091 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Ubiq_cyt_C_chap PF03981.12 KFP11529.1 - 4.3e-42 143.5 0.1 6e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Chlorophyllase PF07224.11 KFP11529.1 - 0.095 11.7 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 Chlorophyllase TGF_beta PF00019.20 KFP11530.1 - 3.5e-33 114.7 0.7 6.8e-33 113.8 0.7 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP11530.1 - 1.9e-18 67.1 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide Bromo_TP PF07524.13 KFP11531.1 - 7e-22 77.2 0.3 1.4e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated MAGE_N PF12440.8 KFP11531.1 - 0.81 10.4 5.2 7.4 7.3 0.1 2.6 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal Dicer_dimer PF03368.14 KFP11532.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 KFP11532.1 - 0.0039 17.9 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribosomal_L33 PF00471.20 KFP11534.1 - 0.011 16.1 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L33 PfkB PF00294.24 KFP11535.1 - 7.4e-60 202.8 0.1 8.1e-60 202.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFP11535.1 - 2.3e-06 27.2 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CoA_binding_2 PF13380.6 KFP11535.1 - 0.0027 18.2 0.1 0.02 15.4 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain BRE PF06113.12 KFP11536.1 - 5.5e-140 465.7 0.0 6.3e-140 465.5 0.0 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.26 KFP11536.1 - 0.012 15.3 2.5 1.5 8.4 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-conjugating enzyme Ank PF00023.30 KFP11536.1 - 0.09 13.3 0.1 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat UL17 PF17640.2 KFP11536.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized UL17 bZIP_1 PF00170.21 KFP11537.1 - 5.4e-09 36.0 19.7 8.9e-09 35.3 19.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP11537.1 - 1.1e-05 25.4 19.3 1.9e-05 24.6 19.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP11537.1 - 2.8e-05 24.5 14.1 4.8e-05 23.8 14.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 KFP11537.1 - 0.00053 19.6 0.9 0.00071 19.2 0.9 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 UPF0242 PF06785.11 KFP11537.1 - 0.033 14.3 5.8 0.049 13.7 5.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5320 PF17253.2 KFP11537.1 - 0.41 11.7 2.0 0.69 11.0 2.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) APG6_N PF17675.1 KFP11537.1 - 1.5 9.4 13.9 2.8 8.5 13.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region PEHE PF15275.6 KFP11537.1 - 1.7 9.3 8.5 0.22 12.1 4.0 1.9 2 0 0 2 2 2 0 PEHE domain Spc7 PF08317.11 KFP11537.1 - 2.5 6.9 10.6 3.6 6.4 10.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_G5 PF04599.12 KFP11537.1 - 4.5 6.2 4.3 6.1 5.7 4.3 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Lipase_GDSL PF00657.22 KFP11538.1 - 5.2e-78 261.6 0.0 1.9e-26 93.3 0.0 3.2 3 0 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFP11538.1 - 2.7e-27 96.3 3.1 1.7e-08 35.1 0.4 4.5 3 3 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family DUF4278 PF14105.6 KFP11538.1 - 0.0048 17.3 1.2 4.3 7.8 0.1 4.1 3 2 0 3 3 3 1 Domain of unknown function (DUF4278) RecR PF02132.15 KFP11538.1 - 0.16 11.6 1.8 46 3.7 0.1 3.7 3 0 0 3 3 3 0 RecR protein Metallophos PF00149.28 KFP11539.1 - 1.4e-39 136.7 0.1 1.8e-39 136.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFP11539.1 - 3.3e-17 62.6 0.8 5.6e-17 61.9 0.4 1.6 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain EF-hand_1 PF00036.32 KFP11540.1 - 5.9e-44 144.4 9.7 3.8e-10 38.6 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP11540.1 - 5.9e-37 126.0 3.0 2.1e-19 69.7 0.8 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP11540.1 - 4.7e-35 119.2 9.9 4.2e-15 55.3 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFP11540.1 - 6e-32 106.8 5.0 1.1e-09 37.4 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP11540.1 - 7.3e-28 94.8 6.8 1.1e-06 27.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFP11540.1 - 5.6e-16 58.6 0.2 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP11540.1 - 1.5e-09 37.7 0.5 4.3e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP11540.1 - 5.4e-08 33.2 0.0 0.003 17.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFP11540.1 - 2.1e-06 28.5 0.0 0.0008 20.3 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFP11540.1 - 9.8e-06 25.5 0.0 0.037 14.0 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFP11540.1 - 2.1e-05 24.5 0.2 6.9e-05 22.9 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFP11540.1 - 0.00015 21.8 4.3 0.026 14.7 0.3 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 KFP11540.1 - 0.00074 19.2 1.6 0.00087 19.0 1.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KFP11540.1 - 0.00078 19.4 0.8 0.65 9.9 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 KFP11540.1 - 0.0018 18.2 0.4 0.49 10.4 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFP11540.1 - 0.0039 17.5 1.2 1.5 9.2 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 KFP11540.1 - 0.0052 15.4 0.0 0.0053 15.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFP11540.1 - 0.0062 16.4 0.7 0.33 10.8 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain Poly_export PF02563.16 KFP11540.1 - 0.0089 16.2 0.1 0.55 10.5 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KFP11540.1 - 0.011 16.2 0.0 0.78 10.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) EF-hand_14 PF17959.1 KFP11540.1 - 0.019 15.3 0.1 8 6.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFP11540.1 - 0.043 13.6 0.3 0.65 9.8 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 KFP11540.1 - 0.047 13.8 0.4 0.78 9.9 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.14 KFP11540.1 - 0.063 12.9 0.5 0.25 11.0 0.5 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 KFP11540.1 - 0.066 13.2 0.1 6.8 6.8 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain dCache_2 PF08269.11 KFP11540.1 - 0.079 12.1 0.1 6.2 5.9 0.1 2.4 1 1 1 2 2 2 0 Cache domain RuvA_C PF07499.13 KFP11540.1 - 0.1 13.1 0.1 11 6.5 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFP11540.1 - 0.18 11.8 0.1 6.2 7.0 0.0 2.5 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family LSM PF01423.22 KFP11541.1 - 5.7e-14 51.6 0.0 9.1e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain PDEase_I PF00233.19 KFP11542.1 - 4.1e-92 308.2 4.9 5.7e-92 307.7 4.9 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KFP11542.1 - 1.2e-06 29.1 0.5 2.8e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) DUF4474 PF14751.6 KFP11542.1 - 0.19 11.1 0.4 4.2 6.7 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4474) Ras PF00071.22 KFP11543.1 - 6.1e-52 175.5 0.3 7.1e-52 175.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11543.1 - 5.8e-34 116.9 0.5 7.2e-34 116.6 0.5 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11543.1 - 3.5e-14 52.6 0.1 4.4e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP11543.1 - 2.7e-05 23.7 0.0 3.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP11543.1 - 8.1e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP11543.1 - 0.00049 19.5 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP11543.1 - 0.0037 16.8 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KFP11543.1 - 0.0087 15.8 0.6 0.019 14.7 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP11543.1 - 0.058 13.8 0.0 0.089 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFP11543.1 - 0.058 12.5 0.3 3 6.9 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Mpv17_PMP22 PF04117.12 KFP11544.1 - 5.1e-32 109.9 0.7 8.4e-32 109.2 0.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family PI3K_P85_iSH2 PF16454.5 KFP11545.1 - 1.1e-60 203.9 22.3 1.6e-60 203.3 22.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFP11545.1 - 6e-41 138.4 0.1 8.6e-20 70.6 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFP11545.1 - 1e-25 90.4 0.9 1e-24 87.1 0.0 2.7 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 KFP11545.1 - 9e-05 22.0 1.1 0.0071 15.9 0.0 3.4 4 0 0 4 4 4 1 SH3 domain SH3_9 PF14604.6 KFP11545.1 - 0.00065 19.5 0.2 0.0023 17.7 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain ATG11 PF10377.9 KFP11545.1 - 0.022 14.8 0.8 0.022 14.8 0.8 2.0 2 0 0 2 2 2 0 Autophagy-related protein 11 BRE1 PF08647.11 KFP11545.1 - 3.2 7.9 15.4 0.14 12.2 6.7 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1908 PF08926.11 KFP11546.1 - 1.2e-132 441.3 0.6 1.2e-132 441.3 0.6 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFP11546.1 - 7.8e-58 195.9 0.2 2.1e-57 194.5 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11546.1 - 7.9e-23 81.1 0.0 2e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFP11546.1 - 2.4e-11 43.3 0.1 4.9e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP11546.1 - 2.5e-08 34.1 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP11546.1 - 2.2e-06 27.9 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.6 KFP11546.1 - 0.00038 19.9 0.0 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP11546.1 - 0.0025 17.8 0.0 0.064 13.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.6 KFP11546.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFP11546.1 - 0.018 14.0 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP11546.1 - 0.093 11.5 0.0 0.093 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RhoGAP PF00620.27 KFP11547.1 - 9.8e-36 122.9 0.4 9.8e-36 122.9 0.4 1.7 2 0 0 2 2 2 1 RhoGAP domain NUC173 PF08161.12 KFP11548.1 - 1.6e-43 148.8 0.3 2.6e-39 135.0 0.0 3.5 3 1 0 3 3 3 2 NUC173 domain NAM-associated PF14303.6 KFP11548.1 - 1.5 9.6 9.6 0.061 14.0 3.5 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Ribosomal_L37 PF08561.10 KFP11548.1 - 6.1 7.4 9.4 0.7 10.4 4.3 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 GAS2 PF02187.17 KFP11549.1 - 1.1e-27 96.0 0.1 1.8e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFP11549.1 - 3.4e-14 52.9 0.0 5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Anoctamin PF04547.12 KFP11551.1 - 9.3e-167 555.4 21.3 1.1e-166 555.1 21.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP11551.1 - 2.5e-66 223.6 0.1 3.9e-66 223.0 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ctr PF04145.15 KFP11551.1 - 0.6 10.7 5.8 0.31 11.6 0.4 2.9 3 0 0 3 3 3 0 Ctr copper transporter family HSP70 PF00012.20 KFP11552.1 - 7.4e-173 576.0 10.4 8.6e-165 549.3 0.3 2.7 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFP11552.1 - 1.4e-08 33.9 0.0 2.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Presenilin PF01080.17 KFP11552.1 - 3 6.5 6.2 5.8 5.6 6.2 1.5 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KFP11553.1 - 2.1e-38 132.1 26.9 3.8e-31 108.3 15.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP11553.1 - 7.8e-10 38.2 9.5 7.8e-10 38.2 9.5 3.6 3 1 0 3 3 3 3 Sugar (and other) transporter SLATT_5 PF18160.1 KFP11553.1 - 0.17 11.2 1.0 0.53 9.6 1.0 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Pam17 PF08566.10 KFP11553.1 - 0.44 10.4 4.2 3.9 7.3 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 zf-HC5HC2H_2 PF13832.6 KFP11554.1 - 1.2e-32 112.4 2.8 1.2e-32 112.4 2.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP11554.1 - 4e-28 97.5 2.1 4e-28 97.5 2.1 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP11554.1 - 7.9e-13 47.7 6.4 7.9e-13 47.7 6.4 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 KFP11554.1 - 9.7e-12 44.6 23.2 2.2e-10 40.3 8.7 3.2 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFP11554.1 - 3.5e-06 27.5 0.1 3.5e-06 27.5 0.1 3.5 3 1 0 3 3 3 1 Enhancer of polycomb-like C1_1 PF00130.22 KFP11554.1 - 0.0016 18.3 3.0 0.0016 18.3 3.0 3.2 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFP11554.1 - 0.0062 16.8 18.7 0.14 12.5 4.8 3.6 3 0 0 3 3 3 2 C1 domain zf-RING-like PF08746.11 KFP11554.1 - 0.021 15.1 4.6 0.021 15.1 4.6 3.2 2 0 0 2 2 2 0 RING-like domain FidL_like PF15941.5 KFP11554.1 - 0.06 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 FidL-like putative membrane protein Prok-RING_1 PF14446.6 KFP11554.1 - 2.2 8.3 17.8 0.83 9.6 7.4 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFP11554.1 - 8.1 6.9 21.3 0.29 11.5 2.1 3.0 2 1 0 2 2 2 0 Ring finger domain HpcH_HpaI PF03328.14 KFP11555.1 - 4.1e-49 166.7 0.0 5.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KFP11555.1 - 1.3e-10 40.9 0.0 7.9e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold zf_ZIC PF18366.1 KFP11556.1 - 6.9e-26 90.1 1.3 6.9e-26 90.1 1.3 3.9 4 1 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFP11556.1 - 3.9e-23 80.5 29.6 4.4e-06 26.9 0.2 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP11556.1 - 1.9e-16 59.7 18.6 6.5e-08 32.7 0.3 6.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP11556.1 - 5.4e-09 36.1 41.2 0.0055 17.4 0.2 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP11556.1 - 1.7e-06 28.1 16.3 0.059 13.7 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP11556.1 - 6.2e-05 23.2 13.3 0.0013 19.0 0.7 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP11556.1 - 0.0073 16.6 12.8 0.078 13.3 1.7 3.0 1 1 2 3 3 3 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFP11556.1 - 0.73 10.5 15.0 14 6.4 0.0 5.0 2 2 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFP11556.1 - 0.82 9.7 22.7 0.74 9.9 1.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP11556.1 - 5.4 6.9 20.9 5.6 6.8 0.0 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain CPSase_L_D2 PF02786.17 KFP11557.1 - 6.7e-81 270.8 0.0 1.1e-80 270.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFP11557.1 - 7.3e-37 125.8 0.0 1.4e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFP11557.1 - 1.2e-29 103.1 0.6 4.1e-29 101.3 0.3 2.1 2 1 0 2 2 2 1 Biotin carboxylase, N-terminal domain PCC_BT PF18140.1 KFP11557.1 - 3e-18 66.4 0.0 9.6e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 KFP11557.1 - 3.5e-07 30.0 0.1 1.5e-06 27.9 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFP11557.1 - 3.1e-06 26.9 0.1 9.1e-06 25.3 0.1 1.8 1 1 1 2 2 2 1 ATP-grasp domain RimK PF08443.11 KFP11557.1 - 3.3e-05 23.6 0.0 7.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain SLT_beta PF02258.16 KFP11557.1 - 0.0074 16.3 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Shiga-like toxin beta subunit ATP-grasp_5 PF13549.6 KFP11557.1 - 0.013 14.9 0.1 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KFP11557.1 - 0.067 12.4 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KFP11557.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain EF-hand_1 PF00036.32 KFP11558.1 - 9e-44 143.8 9.7 4.2e-10 38.4 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP11558.1 - 3.8e-37 126.6 2.5 2.5e-19 69.5 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP11558.1 - 4.5e-35 119.3 9.8 4.8e-15 55.1 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFP11558.1 - 8.5e-32 106.4 4.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP11558.1 - 1.1e-27 94.3 6.8 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFP11558.1 - 7.5e-16 58.2 0.2 2.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP11558.1 - 2.5e-10 40.2 0.4 5.1e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP11558.1 - 3.7e-08 33.7 0.0 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KFP11558.1 - 2e-06 28.6 0.0 0.00083 20.2 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFP11558.1 - 1.1e-05 25.3 0.0 0.042 13.9 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFP11558.1 - 1.5e-05 25.0 1.0 8.1e-05 22.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KFP11558.1 - 0.00024 21.2 4.5 0.036 14.2 0.3 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF1103 PF06513.11 KFP11558.1 - 0.00071 19.3 1.4 0.00082 19.0 1.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KFP11558.1 - 0.00084 19.3 0.8 0.83 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 KFP11558.1 - 0.0013 19.5 0.5 2.3 9.1 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 KFP11558.1 - 0.002 18.6 0.0 0.88 10.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 KFP11558.1 - 0.0024 17.9 0.8 0.57 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFP11558.1 - 0.0031 17.8 0.7 1.7 9.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 KFP11558.1 - 0.0056 15.3 0.0 0.0056 15.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KFP11558.1 - 0.0074 16.2 0.8 0.39 10.6 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain Poly_export PF02563.16 KFP11558.1 - 0.011 15.9 0.1 0.56 10.5 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 KFP11558.1 - 0.024 15.0 0.1 9.1 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 KFP11558.1 - 0.043 13.6 0.4 0.56 10.0 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 KFP11558.1 - 0.044 13.4 0.8 0.19 11.3 0.8 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 KFP11558.1 - 0.052 13.7 0.3 0.95 9.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KFP11558.1 - 0.077 12.2 0.2 6.8 5.8 0.1 2.4 1 1 1 2 2 2 0 Cache domain TetR_C_7 PF14246.6 KFP11558.1 - 0.083 12.9 0.1 7.2 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 KFP11558.1 - 0.13 12.8 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain CMD PF02627.20 KFP11558.1 - 0.29 11.2 1.0 7 6.8 0.0 2.8 2 2 1 4 4 3 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 KFP11558.1 - 0.37 10.9 1.6 27 4.9 0.0 3.4 4 0 0 4 4 4 0 Saposin-like type B, region 1 NRDE-2 PF08424.10 KFP11559.1 - 2.9e-107 358.5 2.9 2.9e-107 358.5 2.9 3.9 5 1 1 6 6 6 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KFP11559.1 - 1.4e-09 38.0 1.2 0.28 12.1 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP11559.1 - 0.00041 20.8 0.1 0.97 10.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat BshC PF10079.9 KFP11559.1 - 0.021 13.6 0.0 0.057 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Dsh_C PF12316.8 KFP11559.1 - 0.83 10.0 5.2 1.6 9.1 5.2 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal TPR_2 PF07719.17 KFP11559.1 - 1.9 8.8 8.2 4.3 7.7 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP11559.1 - 2.4 9.0 4.6 57 4.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Coilin_N PF15862.5 KFP11559.1 - 7.7 6.3 13.8 10 5.9 9.5 2.7 2 0 0 2 2 2 0 Coilin N-terminus AAA PF00004.29 KFP11560.1 - 1e-32 113.3 0.1 1.4e-30 106.4 0.1 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP11560.1 - 5.3e-11 42.1 0.6 9.9e-11 41.3 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KFP11560.1 - 5e-10 39.2 0.2 9.8e-10 38.2 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KFP11560.1 - 7.5e-07 29.4 0.1 2.4e-06 27.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFP11560.1 - 2.1e-05 23.8 0.0 3.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFP11560.1 - 4.3e-05 23.8 0.1 0.0023 18.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP11560.1 - 5.4e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFP11560.1 - 6.7e-05 23.3 0.1 0.0028 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFP11560.1 - 0.00013 22.0 0.2 0.00073 19.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 KFP11560.1 - 0.002 17.5 0.2 0.25 10.7 0.0 2.5 2 1 1 3 3 3 1 KaiC IstB_IS21 PF01695.17 KFP11560.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFP11560.1 - 0.0035 17.5 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFP11560.1 - 0.0055 16.6 0.1 0.098 12.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFP11560.1 - 0.0056 16.3 0.3 0.33 10.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 KFP11560.1 - 0.0057 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFP11560.1 - 0.0065 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KFP11560.1 - 0.0077 16.8 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFP11560.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFP11560.1 - 0.013 15.5 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFP11560.1 - 0.015 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KFP11560.1 - 0.018 14.7 0.1 0.056 13.1 0.0 1.9 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain AAA_7 PF12775.7 KFP11560.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFP11560.1 - 0.032 14.0 0.3 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFP11560.1 - 0.034 14.1 0.1 0.56 10.1 0.0 2.6 2 1 1 3 3 3 0 NACHT domain PhoH PF02562.16 KFP11560.1 - 0.036 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.22 KFP11560.1 - 0.043 13.9 0.0 9.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.6 KFP11560.1 - 0.052 13.3 1.3 0.084 12.6 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFP11560.1 - 0.06 13.1 0.2 0.15 11.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain DivIC PF04977.15 KFP11560.1 - 0.061 13.1 0.1 2 8.2 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator ABC_tran PF00005.27 KFP11560.1 - 0.061 13.8 0.1 0.23 12.0 0.1 2.1 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KFP11560.1 - 0.067 13.1 0.8 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFP11560.1 - 0.07 12.3 0.2 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KFP11560.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KFP11560.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ion_trans_2 PF07885.16 KFP11561.1 - 6.4e-19 67.7 23.2 1e-14 54.2 8.3 2.3 2 0 0 2 2 2 2 Ion channel LPG_synthase_TM PF03706.13 KFP11561.1 - 0.066 12.7 1.6 0.11 12.0 1.6 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Ion_trans PF00520.31 KFP11561.1 - 0.27 10.4 16.4 0.061 12.5 5.2 2.2 2 0 0 2 2 2 0 Ion transport protein Tyr-DNA_phospho PF06087.12 KFP11562.1 - 7.6e-138 460.0 0.0 9.4e-138 459.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase FAM60A PF15396.6 KFP11563.1 - 8.6e-83 277.5 10.4 1.1e-82 277.2 10.4 1.1 1 0 0 1 1 1 1 Protein Family FAM60A DENN PF02141.21 KFP11564.1 - 4.6e-63 212.5 5.4 1.5e-62 210.9 3.8 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.19 KFP11564.1 - 4.1e-41 140.1 6.0 3e-20 72.6 3.3 2.9 3 0 0 3 3 3 2 RUN domain dDENN PF03455.19 KFP11564.1 - 6.3e-18 64.5 2.9 6.3e-18 64.5 2.9 2.3 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 KFP11564.1 - 5.7e-14 52.6 0.0 1.6e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 uDENN domain PLAT PF01477.23 KFP11564.1 - 1.7e-11 44.7 0.0 3.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain PrmA PF06325.13 KFP11565.1 - 2.5e-10 40.2 0.1 3.6e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KFP11565.1 - 5.3e-09 36.0 0.0 1.6e-08 34.5 0.0 1.7 2 1 0 2 2 2 1 Lysine methyltransferase Met_10 PF02475.16 KFP11565.1 - 0.00024 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KFP11565.1 - 0.0037 16.8 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KFP11565.1 - 0.044 13.4 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFP11565.1 - 0.11 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LRR_6 PF13516.6 KFP11566.1 - 5.8e-12 44.6 11.2 0.29 11.3 0.0 7.2 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KFP11566.1 - 2.4e-05 24.6 5.4 0.0053 17.2 1.1 4.3 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP11566.1 - 0.0019 18.5 3.5 89 4.3 0.1 5.3 4 2 0 4 4 4 0 Leucine Rich Repeat DUF4617 PF15395.6 KFP11568.1 - 0 1054.2 105.8 0 1054.2 105.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4617) BicD PF09730.9 KFP11569.1 - 0 1142.0 63.1 0 1141.8 63.1 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Med4 PF10018.9 KFP11569.1 - 0.00061 19.5 1.3 0.00061 19.5 1.3 5.4 4 2 1 5 5 5 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1759 PF03564.15 KFP11569.1 - 0.0019 18.2 6.0 0.0019 18.2 6.0 5.2 4 1 0 5 5 5 1 Protein of unknown function (DUF1759) ADIP PF11559.8 KFP11569.1 - 0.0074 16.4 7.1 0.0074 16.4 7.1 6.4 4 2 2 7 7 7 2 Afadin- and alpha -actinin-Binding ApoO PF09769.9 KFP11569.1 - 0.047 13.7 0.5 0.047 13.7 0.5 3.8 3 2 0 3 3 3 0 Apolipoprotein O Spc7 PF08317.11 KFP11569.1 - 5.7 5.7 85.3 0.25 10.2 8.1 5.7 4 2 0 4 4 4 0 Spc7 kinetochore protein 7tm_4 PF13853.6 KFP11571.1 - 2.8e-45 155.2 14.3 3.2e-45 155.0 14.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11571.1 - 2e-30 106.0 14.3 3.3e-30 105.3 14.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11571.1 - 8.1e-05 22.1 12.6 0.00013 21.4 12.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PqiA PF04403.13 KFP11571.1 - 0.55 10.1 11.1 0.029 14.2 4.9 2.0 3 0 0 3 3 3 0 Paraquat-inducible protein A DUF1980 PF09323.10 KFP11571.1 - 5.9 6.8 5.7 1.8 8.4 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) 7tm_4 PF13853.6 KFP11572.1 - 6.3e-24 85.2 6.7 7.2e-24 85.0 6.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11572.1 - 1.1e-06 28.2 10.1 1.5e-06 27.7 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2417 PF10329.9 KFP11572.1 - 0.41 10.0 6.1 0.47 9.8 6.1 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF1980 PF09323.10 KFP11572.1 - 0.52 10.2 3.1 0.37 10.7 1.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4519 PF15012.6 KFP11572.1 - 0.92 9.7 0.0 0.92 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) DUF2633 PF11119.8 KFP11572.1 - 1.2 9.0 3.7 2.5 8.1 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) 7tm_4 PF13853.6 KFP11573.1 - 1.6e-23 83.8 15.6 7.4e-16 58.7 8.4 2.1 1 1 1 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFP11573.1 - 8e-11 41.8 14.9 4.8e-05 22.8 0.2 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11574.1 - 1e-47 163.2 10.8 1.2e-47 163.0 10.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11574.1 - 3.9e-31 108.4 12.5 5.8e-31 107.8 12.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11574.1 - 0.0014 18.1 8.9 0.0031 16.9 8.6 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP11574.1 - 0.02 14.5 9.4 0.073 12.7 9.4 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx CholecysA-Rec_N PF09193.10 KFP11574.1 - 0.064 13.3 0.2 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFP11575.1 - 6.5e-43 147.4 14.5 7.8e-43 147.2 14.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11575.1 - 1.8e-28 99.6 14.0 2.6e-28 99.1 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11575.1 - 0.0019 17.6 11.9 0.0029 17.0 11.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Rax2 PF12768.7 KFP11575.1 - 0.17 11.3 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity 7tm_4 PF13853.6 KFP11576.1 - 2.3e-45 155.5 6.6 2.6e-45 155.4 6.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11576.1 - 6.2e-23 81.5 11.9 1.1e-22 80.7 11.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rax2 PF12768.7 KFP11576.1 - 0.032 13.7 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Stevor PF17410.2 KFP11576.1 - 0.22 11.0 0.4 0.47 9.9 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame 7tm_4 PF13853.6 KFP11577.1 - 1.8e-45 155.8 13.2 2.1e-45 155.6 13.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11577.1 - 8.6e-32 110.5 15.2 1.2e-31 110.0 15.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11577.1 - 7.9e-05 22.2 12.0 0.00014 21.4 11.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11578.1 - 2.3e-49 168.6 13.4 2.6e-49 168.4 13.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11578.1 - 4e-28 98.5 14.9 5.3e-28 98.1 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11578.1 - 0.00095 18.6 14.4 0.0015 18.0 14.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CholecysA-Rec_N PF09193.10 KFP11578.1 - 0.14 12.2 0.3 1.7 8.7 0.0 2.5 3 0 0 3 3 3 0 Cholecystokinin A receptor, N-terminal UL41A PF17591.2 KFP11578.1 - 0.29 11.3 2.4 0.76 9.9 2.4 1.7 1 0 0 1 1 1 0 Herpesvirus UL41A 7tm_4 PF13853.6 KFP11579.1 - 4.3e-47 161.2 13.9 5.1e-47 160.9 13.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11579.1 - 2.8e-28 99.0 12.8 4.1e-28 98.4 12.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11579.1 - 0.00032 20.2 9.4 0.00052 19.5 9.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11580.1 - 1.4e-48 166.0 8.4 1.7e-48 165.8 8.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11580.1 - 7.9e-29 100.8 12.0 1e-28 100.4 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11580.1 - 1.4e-05 24.6 3.8 1.4e-05 24.6 3.8 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP11580.1 - 0.00057 19.6 2.3 0.00057 19.6 2.3 1.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Adipogenin PF15202.6 KFP11580.1 - 4.3 7.4 8.1 1.7 8.7 1.4 2.8 2 1 0 2 2 2 0 Adipogenin Pkinase PF00069.25 KFP11581.1 - 1e-72 244.7 0.0 1.5e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11581.1 - 1.6e-45 155.5 0.0 2.5e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP11581.1 - 1.2e-23 83.2 0.0 3.3e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP11581.1 - 1.5e-07 31.0 0.1 0.00034 20.0 0.0 2.6 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFP11581.1 - 1.8e-06 27.0 0.9 5e-06 25.6 0.9 1.9 1 1 0 1 1 1 1 Fungal protein kinase Spt5_N PF11942.8 KFP11581.1 - 0.00095 20.1 2.3 0.0022 18.9 2.3 1.6 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal APH PF01636.23 KFP11581.1 - 0.0057 16.6 0.1 0.068 13.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.12 KFP11581.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 KFP11581.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP11581.1 - 0.71 8.7 2.8 0.72 8.7 0.4 2.1 2 1 0 2 2 2 0 Haspin like kinase domain Peptidase_C2 PF00648.21 KFP11582.1 - 2.5e-119 397.7 0.4 3.7e-119 397.2 0.4 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP11582.1 - 2.2e-32 112.3 0.0 3.6e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 KFP11582.1 - 8.3e-13 48.5 0.1 3e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 C2 domain DCX PF03607.17 KFP11583.1 - 2.3e-43 146.1 0.1 4e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Doublecortin MGC-24 PF05283.11 KFP11583.1 - 0.081 13.4 4.9 0.095 13.2 1.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2457 PF10446.9 KFP11583.1 - 3.4 6.7 11.4 0.21 10.7 6.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Glyco_tran_28_C PF04101.16 KFP11584.1 - 1.6e-10 41.2 0.0 1.6e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3939 PF13075.6 KFP11584.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3939) Ion_trans PF00520.31 KFP11585.1 - 1e-29 103.5 11.8 1.5e-29 102.9 11.8 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFP11585.1 - 8.6e-29 99.6 0.3 1.9e-28 98.5 0.3 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 KFP11585.1 - 1.4e-10 41.6 1.1 4e-06 27.3 0.5 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP11585.1 - 1.3e-07 32.0 0.0 0.022 15.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP11585.1 - 3.7e-06 26.9 3.3 0.23 12.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFP11585.1 - 0.00019 21.8 1.8 0.099 13.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP11585.1 - 0.00042 20.5 0.4 1.1 9.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KFP11585.1 - 0.0005 18.9 13.0 0.0084 14.8 13.0 2.6 1 1 0 1 1 1 1 Polycystin cation channel Gp-FAR-1 PF05823.12 KFP11585.1 - 0.11 12.8 12.2 1.1 9.7 1.1 3.4 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PGK PF00162.19 KFP11586.1 - 2.1e-143 477.9 1.2 2.3e-143 477.7 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HMA PF00403.26 KFP11587.1 - 3.7e-87 286.7 19.9 7.5e-16 58.3 0.2 7.6 7 0 0 7 7 7 7 Heavy-metal-associated domain Hydrolase PF00702.26 KFP11587.1 - 7.2e-60 202.9 0.2 1.6e-59 201.8 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP11587.1 - 3.1e-40 137.6 3.0 3.1e-40 137.6 3.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP11587.1 - 1e-05 25.4 1.5 0.00062 19.6 0.8 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 KFP11587.1 - 0.0045 17.0 0.1 1.2e+02 2.8 0.0 5.4 6 0 0 6 6 6 0 RNA binding motif Hydrolase_6 PF13344.6 KFP11587.1 - 0.014 15.4 0.2 0.089 12.9 0.1 2.5 2 0 0 2 2 1 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP11587.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RRM_occluded PF16842.5 KFP11587.1 - 0.82 9.6 3.6 0.93 9.4 0.1 2.9 4 0 0 4 4 4 0 Occluded RNA-recognition motif DUF2997 PF11211.8 KFP11587.1 - 2.9 7.7 17.4 0.98 9.3 0.2 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2997) Germane PF10646.9 KFP11587.1 - 3.9 8.3 4.9 46 4.9 0.0 4.2 4 1 0 4 4 4 0 Sporulation and spore germination Spore_YhcN_YlaJ PF09580.10 KFP11587.1 - 5.3 7.1 8.2 23 5.0 0.1 3.6 4 0 0 4 4 4 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) COX7B PF05392.11 KFP11588.1 - 1.1e-39 133.9 0.0 1.2e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB FGF PF00167.18 KFP11589.1 - 4.8e-34 117.2 0.1 5.4e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor MecA PF05389.12 KFP11589.1 - 0.18 11.4 0.1 0.21 11.2 0.1 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DHHC PF01529.20 KFP11590.1 - 4e-13 49.6 14.1 5.5e-13 49.2 12.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase TLV_coat PF00429.19 KFP11591.1 - 0.019 13.7 0.2 0.021 13.5 0.2 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) 7tm_4 PF13853.6 KFP11592.1 - 8.8e-48 163.4 9.4 1.1e-47 163.2 9.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11592.1 - 7.8e-29 100.8 10.7 1.1e-28 100.4 10.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11593.1 - 5.9e-47 160.7 9.5 6.9e-47 160.5 9.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11593.1 - 1.4e-29 103.2 7.8 2e-29 102.7 7.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP11593.1 - 0.013 15.2 3.5 0.013 15.2 3.5 1.7 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP11593.1 - 0.025 13.9 8.2 0.017 14.5 4.9 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11594.1 - 4.1e-42 144.8 12.9 5.1e-42 144.5 12.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11594.1 - 1.7e-27 96.4 14.6 3.1e-27 95.6 14.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11595.1 - 2.4e-43 148.9 14.7 2.9e-43 148.6 14.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11595.1 - 6.5e-31 107.6 14.0 9.7e-31 107.0 14.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11596.1 - 6.2e-40 137.7 13.8 7.3e-40 137.5 13.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11596.1 - 4.1e-31 108.3 13.9 5.5e-31 107.8 13.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1980 PF09323.10 KFP11596.1 - 7.1 6.5 6.1 2.8 7.8 1.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) 7tm_4 PF13853.6 KFP11597.1 - 7.2e-44 150.6 22.3 8.7e-44 150.3 22.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11597.1 - 1.4e-23 83.6 22.9 1.9e-23 83.1 22.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11597.1 - 6.2e-07 29.0 13.7 6.2e-07 29.0 13.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11598.1 - 2.2e-46 158.9 13.0 2.6e-46 158.6 13.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP11598.1 - 1e-29 103.7 14.5 1.4e-29 103.3 14.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 KFP11599.1 - 2.2e-76 256.7 0.0 3.4e-76 256.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11599.1 - 3.4e-40 138.0 0.0 1.6e-39 135.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP11599.1 - 7.8e-06 25.4 1.5 8e-05 22.1 0.0 2.5 2 1 1 3 3 3 1 Kinase-like RIO1 PF01163.22 KFP11599.1 - 0.00054 19.6 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFP11599.1 - 0.00081 18.4 0.0 0.00081 18.4 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFP11599.1 - 0.001 18.5 0.1 0.0024 17.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP11599.1 - 0.025 14.5 0.0 0.28 11.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family AP1AR PF15745.5 KFP11600.1 - 6.7e-151 501.5 16.6 7.5e-151 501.4 16.6 1.0 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein PA26 PF04636.13 KFP11600.1 - 9 5.1 9.2 2.4 7.0 6.0 1.5 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) FHA PF00498.26 KFP11601.1 - 0.0005 20.4 0.0 0.00069 19.9 0.0 1.2 1 0 0 1 1 1 1 FHA domain Alpha_kinase PF02816.18 KFP11602.1 - 2e-46 158.4 1.2 4.4e-46 157.3 1.2 1.6 1 0 0 1 1 1 1 Alpha-kinase family AAA_12 PF13087.6 KFP11603.1 - 6.9e-53 179.2 0.1 2.5e-52 177.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP11603.1 - 7.4e-26 91.5 0.0 1.7e-18 67.4 0.3 2.4 1 1 1 2 2 2 2 AAA domain zf-GRF PF06839.12 KFP11603.1 - 3e-15 56.0 0.4 7e-15 54.8 0.4 1.7 1 0 0 1 1 1 1 GRF zinc finger Viral_helicase1 PF01443.18 KFP11603.1 - 3.8e-08 33.4 0.1 0.037 13.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFP11603.1 - 0.0019 18.0 0.0 0.023 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP11603.1 - 0.0076 16.6 0.0 0.026 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFP11603.1 - 0.11 12.3 0.1 0.35 10.7 0.1 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 KFP11603.1 - 0.15 11.4 0.0 15 4.8 0.2 2.5 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF2439 PF10382.9 KFP11604.1 - 8.3e-17 61.3 0.2 2.2e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) RRM_3 PF08777.11 KFP11605.1 - 1e-27 96.1 0.2 1e-27 96.1 0.2 3.8 5 0 0 5 5 5 2 RNA binding motif La PF05383.17 KFP11605.1 - 7.3e-21 74.0 0.7 2.2e-20 72.4 0.1 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 KFP11605.1 - 4.2e-20 71.3 0.1 6.2e-17 61.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP11605.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ADK PF00406.22 KFP11606.1 - 6.7e-51 172.3 0.0 8e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFP11606.1 - 2.5e-21 76.5 0.0 4.6e-21 75.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KFP11606.1 - 5.5e-17 61.4 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFP11606.1 - 1.9e-06 28.4 0.0 3.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP11606.1 - 0.00018 21.7 0.0 0.00077 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KFP11606.1 - 0.0032 17.2 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 KFP11606.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CDC37_M PF08565.11 KFP11607.1 - 7.5e-20 71.0 0.1 1.5e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain LUC7 PF03194.15 KFP11608.1 - 3.7e-72 243.0 13.5 3.7e-72 243.0 13.5 2.2 1 1 1 2 2 2 1 LUC7 N_terminus TSC22 PF01166.18 KFP11608.1 - 0.49 10.8 3.8 8.8 6.7 0.2 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family PQQ_2 PF13360.6 KFP11609.1 - 4.3e-07 29.8 0.4 0.00017 21.3 0.0 2.9 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KFP11609.1 - 0.0024 17.7 0.0 0.75 9.8 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat FG-GAP PF01839.23 KFP11609.1 - 0.087 13.0 0.7 0.43 10.7 0.3 2.3 2 0 0 2 2 2 0 FG-GAP repeat DUF3413 PF11893.8 KFP11609.1 - 0.11 11.7 0.3 0.16 11.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) VCBS PF13517.6 KFP11609.1 - 0.14 12.7 1.0 1.6 9.4 0.2 2.6 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DIX PF00778.17 KFP11610.1 - 2.6e-31 107.3 1.1 4.6e-31 106.5 1.1 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 KFP11610.1 - 1.4e-27 96.3 0.4 2.8e-27 95.3 0.4 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain AXIN1_TNKS_BD PF16646.5 KFP11610.1 - 2e-25 89.5 3.6 1.3e-24 86.9 3.6 2.6 1 0 0 1 1 1 1 Axin-1 tankyrase binding domain Axin_b-cat_bind PF08833.10 KFP11610.1 - 8e-11 41.9 0.0 3e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 Axin beta-catenin binding domain Cwf_Cwc_15 PF04889.12 KFP11610.1 - 0.8 9.4 5.7 0.44 10.2 1.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3522 PF12036.8 KFP11611.1 - 9.2e-65 218.5 19.3 1.8e-64 217.5 19.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF456 PF04306.13 KFP11611.1 - 0.44 10.8 5.7 0.72 10.1 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF2157 PF09925.9 KFP11611.1 - 4.2 7.1 8.8 2.4 7.9 3.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Globin PF00042.22 KFP11612.1 - 7.3e-28 97.3 0.2 9.5e-28 97.0 0.2 1.1 1 0 0 1 1 1 1 Globin Globin PF00042.22 KFP11614.1 - 4.4e-30 104.5 0.0 6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Globin Pur_DNA_glyco PF02245.16 KFP11615.1 - 6.5e-60 201.6 0.0 7.9e-60 201.3 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Rhomboid_SP PF12595.8 KFP11616.1 - 5.1e-113 375.7 1.7 7.7e-113 375.2 1.7 1.3 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.22 KFP11616.1 - 8.6e-28 97.2 9.1 8.6e-28 97.2 9.1 1.8 2 0 0 2 2 2 1 Rhomboid family Herpes_UL56 PF04534.12 KFP11616.1 - 0.029 13.8 1.2 0.037 13.5 0.2 1.7 2 0 0 2 2 2 0 Herpesvirus UL56 protein DUF4457 PF14652.6 KFP11617.1 - 1.2e-187 622.9 1.4 1.4e-142 474.8 0.0 3.5 3 1 0 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 KFP11617.1 - 4.4e-05 23.5 0.0 6.1 6.9 0.0 4.5 4 0 0 4 4 4 2 Sad1 / UNC-like C-terminal GSG-1 PF07803.11 KFP11618.1 - 5.2e-51 171.4 0.5 9.7e-51 170.6 0.5 1.5 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFP11618.1 - 1.9e-08 34.4 10.6 1.2e-05 25.2 10.6 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP11618.1 - 4.1e-06 26.7 10.9 1.4e-05 24.9 10.8 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tissue_fac PF01108.17 KFP11619.1 - 1.2e-21 76.5 0.1 6.9e-21 74.1 0.0 2.2 3 0 0 3 3 3 1 Tissue factor Interfer-bind PF09294.10 KFP11619.1 - 5.5e-11 42.7 0.6 2.8e-10 40.4 0.6 1.9 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP11619.1 - 0.00086 19.6 0.2 1.2 9.5 0.1 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Ion_trans PF00520.31 KFP11620.1 - 3.8e-256 845.0 80.3 7.3e-78 261.2 17.6 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFP11620.1 - 4.4e-17 61.9 81.9 2.7e-09 36.2 1.8 9.8 5 4 4 9 9 9 6 Polycystin cation channel Shisa PF13908.6 KFP11620.1 - 0.058 13.6 0.8 44 4.2 0.0 4.7 5 1 0 5 5 5 0 Wnt and FGF inhibitory regulator MscL PF01741.18 KFP11620.1 - 0.073 13.4 3.7 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Large-conductance mechanosensitive channel, MscL UPF0542 PF15086.6 KFP11620.1 - 0.19 11.7 15.5 2.8 8.0 0.1 4.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0542 SieB PF14163.6 KFP11620.1 - 8.1 5.9 17.0 0.95 8.9 0.0 4.9 5 0 0 5 5 5 0 Super-infection exclusion protein B NicO PF03824.16 KFP11620.1 - 8.2 5.7 16.1 22 4.3 0.0 3.8 2 1 0 2 2 2 0 High-affinity nickel-transport protein B9-C2 PF07162.11 KFP11621.1 - 2.4e-48 164.5 0.2 2.7e-48 164.3 0.2 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein ENTH PF01417.20 KFP11622.1 - 9.2e-54 180.8 0.2 2.2e-53 179.6 0.2 1.7 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFP11622.1 - 3.6e-06 26.2 0.1 5.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFP11622.1 - 7.6e-05 22.6 0.9 0.00014 21.7 0.3 1.7 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 KFP11622.1 - 1.6 8.9 14.3 0.21 11.6 5.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif SH2 PF00017.24 KFP11623.1 - 4.3e-24 84.4 0.5 6.3e-24 83.9 0.5 1.2 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP11623.1 - 2.1e-13 49.7 0.1 3.7e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP11623.1 - 7.5e-13 48.0 0.0 2.5e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFP11623.1 - 2.9e-11 43.0 0.1 5e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain LydB PF16084.5 KFP11623.1 - 0.039 13.8 0.0 0.83 9.5 0.0 2.1 1 1 0 2 2 2 0 LydA-holin antagonist SSF PF00474.17 KFP11624.1 - 1.3e-122 409.6 16.0 1.3e-122 409.6 16.0 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2569 PF10754.9 KFP11624.1 - 0.069 13.6 0.6 0.069 13.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) T2SSM PF04612.12 KFP11624.1 - 0.18 11.9 0.5 0.4 10.7 0.5 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Pribosyl_synth PF14572.6 KFP11625.1 - 3.7e-101 336.7 1.5 5.7e-101 336.1 1.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP11625.1 - 1.3e-39 134.7 0.5 3.2e-39 133.5 0.5 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP11625.1 - 2.4e-08 33.6 0.1 3e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain RelB PF04221.12 KFP11625.1 - 0.036 14.0 0.1 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RelB antitoxin UN_NPL4 PF11543.8 KFP11625.1 - 0.039 14.4 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 SWC7 PF17330.2 KFP11625.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 7tm_1 PF00001.21 KFP11626.1 - 7.2e-44 150.1 19.3 1.1e-43 149.5 19.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP11626.1 - 0.0016 18.2 11.7 0.0016 18.2 11.7 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TraL PF07178.11 KFP11626.1 - 0.17 12.4 4.3 0.24 11.9 0.1 2.7 2 0 0 2 2 2 0 TraL protein Synaptobrevin PF00957.21 KFP11626.1 - 1.4 8.8 4.6 12 5.8 0.1 2.9 2 1 1 3 3 3 0 Synaptobrevin SHMT PF00464.19 KFP11627.1 - 1.1e-206 686.1 0.0 1.3e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 KFP11627.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Folliculin PF11704.8 KFP11628.1 - 2.1e-08 34.3 0.1 4.1e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Topoisom_bac PF01131.20 KFP11629.1 - 3.1e-116 388.8 0.0 9e-116 387.3 0.0 1.7 2 0 0 2 2 2 1 DNA topoisomerase zf-GRF PF06839.12 KFP11629.1 - 4.1e-37 126.0 21.5 6.7e-20 70.9 5.7 3.5 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 KFP11629.1 - 1.3e-17 63.9 0.0 1.3e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 KFP11629.1 - 2.6e-12 46.3 1.7 2.6e-12 46.3 1.7 3.6 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-C2H2_10 PF16588.5 KFP11629.1 - 0.00041 20.0 2.4 0.0012 18.5 2.4 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KFP11629.1 - 0.011 15.5 5.0 0.048 13.5 5.0 2.2 1 0 0 1 1 1 0 Zinc knuckle Gelsolin PF00626.22 KFP11630.1 - 2.2e-61 203.7 1.3 2.7e-15 56.0 0.0 6.9 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.6 KFP11630.1 - 3.8e-38 129.1 40.0 3.9e-09 36.1 9.4 6.6 5 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP11630.1 - 3e-20 71.9 58.2 3.2e-06 27.4 4.9 8.5 2 1 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP11630.1 - 0.00083 18.9 20.9 0.11 12.0 1.1 4.2 1 1 3 4 4 4 3 Leucine-rich repeat SRP-alpha_N PF04086.13 KFP11630.1 - 0.0074 16.2 0.6 0.0074 16.2 0.6 1.9 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal LRR_1 PF00560.33 KFP11630.1 - 0.027 15.0 46.2 2.1 9.2 0.2 11.8 12 1 0 12 12 12 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 KFP11631.1 - 7.9e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ApoO PF09769.9 KFP11631.1 - 0.095 12.7 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O RRM_1 PF00076.22 KFP11638.1 - 9.4e-52 172.7 0.0 6.4e-18 64.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFP11638.1 - 2.1e-10 40.5 0.0 0.089 12.8 0.0 4.0 3 1 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 KFP11638.1 - 6e-05 23.1 0.1 0.35 11.0 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFP11638.1 - 0.00087 19.6 3.0 0.71 10.1 0.1 4.2 3 1 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter RabGAP-TBC PF00566.18 KFP11641.1 - 1.5e-42 145.7 5.7 1.5e-42 145.7 5.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ECH_1 PF00378.20 KFP11643.1 - 1.8e-53 181.4 0.0 2e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP11643.1 - 7.2e-33 114.5 0.0 3e-30 105.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SARG PF15385.6 KFP11644.1 - 5.4e-16 59.0 33.6 4.4e-09 36.1 1.1 3.9 1 1 1 3 3 3 3 Specifically androgen-regulated gene protein MIF4G PF02854.19 KFP11645.1 - 2.3e-75 252.9 26.8 2.9e-43 148.0 0.0 3.9 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 KFP11645.1 - 1e-33 116.9 2.3 1e-33 116.9 2.3 5.7 3 3 1 4 4 4 1 Up-frameshift suppressor 2 Transket_pyr PF02779.24 KFP11646.1 - 8.8e-63 211.2 0.0 1.5e-62 210.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KFP11646.1 - 2.2e-46 157.3 0.0 3.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KFP11646.1 - 1.7e-44 152.0 0.0 3.7e-44 150.9 0.0 1.5 1 1 0 1 1 1 1 Dehydrogenase E1 component SecY PF00344.20 KFP11647.1 - 5.3e-74 249.2 11.4 7.2e-74 248.8 11.4 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFP11647.1 - 8e-19 67.2 0.2 2.3e-18 65.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p D123 PF07065.14 KFP11648.1 - 1.4e-99 333.2 0.2 1.6e-99 333.0 0.2 1.0 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 KFP11648.1 - 0.041 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 ATPgrasp_YheCD PF14398.6 KFP11648.1 - 0.14 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp Pkinase PF00069.25 KFP11650.1 - 2.4e-77 259.9 0.0 2.9e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11650.1 - 2.9e-35 121.8 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP11650.1 - 4.6e-09 36.0 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP11650.1 - 0.00015 21.2 0.1 0.00029 20.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP11650.1 - 0.00017 20.5 0.0 0.00032 19.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFP11650.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFP11650.1 - 0.0014 18.6 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family 5_nucleotid PF05761.14 KFP11650.1 - 0.037 12.9 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family Pox_ser-thr_kin PF05445.11 KFP11650.1 - 0.081 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YscO PF07321.12 KFP11652.1 - 2.3e-06 27.6 8.5 3.6e-06 27.0 8.5 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO ATG16 PF08614.11 KFP11652.1 - 0.00015 22.1 5.4 0.00017 21.9 5.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KFP11652.1 - 0.00026 20.0 4.3 0.00034 19.6 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_1 PF00170.21 KFP11652.1 - 0.00057 19.9 3.8 0.00057 19.9 3.8 1.9 1 1 1 2 2 2 1 bZIP transcription factor Fib_alpha PF08702.10 KFP11652.1 - 0.00086 19.5 3.0 0.0013 19.0 3.0 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 KFP11652.1 - 0.0012 19.1 8.6 0.0018 18.5 8.6 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 KFP11652.1 - 0.0026 17.8 2.2 0.0037 17.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KFP11652.1 - 0.0033 17.6 8.9 0.0044 17.2 8.9 1.1 1 0 0 1 1 1 1 Tropomyosin like FlaC_arch PF05377.11 KFP11652.1 - 0.004 17.5 2.2 0.011 16.2 2.2 1.8 1 1 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KFP11652.1 - 0.0045 16.3 4.0 0.0052 16.1 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMCO5 PF14992.6 KFP11652.1 - 0.005 16.5 4.2 0.0061 16.2 4.2 1.1 1 0 0 1 1 1 1 TMCO5 family BLOC1_2 PF10046.9 KFP11652.1 - 0.005 17.1 2.3 0.009 16.3 2.3 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ax_dynein_light PF10211.9 KFP11652.1 - 0.0084 16.1 9.2 0.011 15.7 9.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF489 PF04356.12 KFP11652.1 - 0.0087 16.1 1.5 0.011 15.8 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Occludin_ELL PF07303.13 KFP11652.1 - 0.0096 16.6 4.9 0.016 16.0 4.9 1.3 1 0 0 1 1 1 1 Occludin homology domain DegS PF05384.11 KFP11652.1 - 0.01 15.3 4.6 0.016 14.7 4.6 1.4 1 0 0 1 1 1 0 Sensor protein DegS Laminin_II PF06009.12 KFP11652.1 - 0.012 15.6 4.1 0.016 15.2 4.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Herpes_UL6 PF01763.16 KFP11652.1 - 0.014 13.9 2.8 0.015 13.8 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like UPF0242 PF06785.11 KFP11652.1 - 0.015 15.4 3.2 0.019 15.1 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uso1_p115_C PF04871.13 KFP11652.1 - 0.019 15.3 5.6 0.03 14.7 5.6 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 KFP11652.1 - 0.023 12.7 1.4 0.024 12.6 1.4 1.1 1 0 0 1 1 1 0 Prominin DUF745 PF05335.13 KFP11652.1 - 0.029 14.1 2.9 0.038 13.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TMPIT PF07851.13 KFP11652.1 - 0.03 13.6 2.5 0.032 13.5 2.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KFP11652.1 - 0.033 13.1 0.4 0.031 13.2 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 KFP11652.1 - 0.033 13.3 6.3 0.035 13.2 6.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 KFP11652.1 - 0.037 14.5 8.7 0.064 13.7 8.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Rho_Binding PF08912.11 KFP11652.1 - 0.04 14.7 5.8 0.04 14.7 5.8 1.6 1 1 0 1 1 1 0 Rho Binding PRKCSH-like PF12999.7 KFP11652.1 - 0.045 13.6 1.4 0.054 13.3 1.4 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like TMF_DNA_bd PF12329.8 KFP11652.1 - 0.051 13.6 9.9 0.089 12.8 9.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KFP11652.1 - 0.058 14.0 4.9 0.14 12.8 4.8 1.7 1 1 0 1 1 1 0 SlyX NPV_P10 PF05531.12 KFP11652.1 - 0.074 13.5 2.3 2.7 8.5 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 KFP11652.1 - 0.076 12.8 7.9 0.12 12.1 7.7 1.5 1 1 0 1 1 1 0 Septum formation initiator GrpE PF01025.19 KFP11652.1 - 0.077 12.7 6.0 0.1 12.2 6.0 1.2 1 0 0 1 1 1 0 GrpE DUF4988 PF16378.5 KFP11652.1 - 0.087 12.5 0.7 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function ADIP PF11559.8 KFP11652.1 - 0.089 12.9 10.5 0.13 12.4 10.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3552 PF12072.8 KFP11652.1 - 0.089 12.2 8.4 0.11 11.9 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) EMP24_GP25L PF01105.24 KFP11652.1 - 0.091 12.7 4.7 0.12 12.4 4.7 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD P4Ha_N PF08336.11 KFP11652.1 - 0.094 12.7 3.6 0.15 12.1 3.6 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region XhlA PF10779.9 KFP11652.1 - 0.13 12.4 4.3 0.21 11.8 3.7 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Exonuc_VII_L PF02601.15 KFP11652.1 - 0.14 11.7 5.1 0.15 11.6 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF773 PF05600.12 KFP11652.1 - 0.15 10.7 9.3 0.2 10.4 9.3 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 YabA PF06156.13 KFP11652.1 - 0.16 12.6 5.9 0.27 11.9 5.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DASH_Dam1 PF08653.10 KFP11652.1 - 0.2 11.5 1.3 6.9 6.6 0.2 2.4 1 1 1 2 2 2 0 DASH complex subunit Dam1 GIT_CC PF16559.5 KFP11652.1 - 0.24 11.3 10.5 0.36 10.7 2.1 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3251 PF11622.8 KFP11652.1 - 0.26 10.9 2.7 0.4 10.3 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) DUF4446 PF14584.6 KFP11652.1 - 0.35 10.8 4.0 0.65 10.0 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TFR_dimer PF04253.15 KFP11652.1 - 0.71 10.0 4.3 2.6 8.2 3.3 1.9 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain betaPIX_CC PF16523.5 KFP11652.1 - 5.7 6.8 11.9 18 5.2 11.9 1.8 1 1 0 1 1 1 0 betaPIX coiled coil CC2-LZ PF16516.5 KFP11653.1 - 1.5e-30 105.5 15.5 1.5e-30 105.5 15.5 5.5 3 2 0 4 4 4 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator NEMO PF11577.8 KFP11653.1 - 1.1e-29 102.3 14.0 1.1e-29 102.3 14.0 5.8 6 1 0 6 6 6 1 NF-kappa-B essential modulator NEMO zf_C2H2_10 PF18414.1 KFP11653.1 - 2.3e-16 59.0 4.5 4.9e-16 57.9 4.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger MLD PF11647.8 KFP11653.1 - 0.019 15.2 3.9 2.3 8.6 0.1 3.5 2 1 1 3 3 3 0 Membrane Localization Domain FGAR-AT_N PF18076.1 KFP11653.1 - 0.12 12.3 3.7 0.78 9.7 3.7 2.5 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal DUF3973 PF13119.6 KFP11653.1 - 0.86 9.7 2.9 16 5.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Mcm10 PF09332.11 KFP11654.1 - 1.3e-150 501.7 11.8 1.3e-150 501.7 11.8 2.8 3 1 1 4 4 4 1 Mcm10 replication factor zf-primase PF09329.11 KFP11654.1 - 1.6e-17 63.0 1.9 4.8e-17 61.5 1.9 1.9 1 0 0 1 1 1 1 Primase zinc finger PhyH PF05721.13 KFP11656.1 - 3.1e-41 142.0 0.0 3.9e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AIRS_C PF02769.22 KFP11657.1 - 5.6e-31 107.8 0.1 8.5e-31 107.2 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFP11657.1 - 9.6e-11 42.2 0.2 2.5e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain BEN PF10523.9 KFP11658.1 - 7.9e-18 64.5 0.1 2.2e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 BEN domain Prp18 PF02840.15 KFP11659.1 - 1.3e-62 210.0 0.1 2.5e-62 209.2 0.1 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 KFP11659.1 - 1.2e-13 50.3 3.5 1.2e-13 50.3 3.5 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like AbiJ_NTD5 PF18865.1 KFP11659.1 - 0.022 14.5 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Phage_int_SAM_4 PF13495.6 KFP11659.1 - 0.12 12.9 0.2 20 5.7 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF1151 PF06625.11 KFP11665.1 - 2.6e-43 146.6 23.6 3.1e-43 146.3 23.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) Hormone_recep PF00104.30 KFP11669.1 - 4.8e-28 98.1 7.0 7.7e-28 97.5 7.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP11669.1 - 1.1e-26 93.0 15.7 1.1e-26 93.0 15.7 1.6 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Prog_receptor PF02161.15 KFP11669.1 - 0.0036 16.1 1.0 0.0047 15.7 1.0 1.1 1 0 0 1 1 1 1 Progesterone receptor DUF1422 PF07226.11 KFP11669.1 - 0.12 12.4 0.2 17 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Pkinase PF00069.25 KFP11671.1 - 1.8e-77 260.3 0.0 2.6e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11671.1 - 5.3e-44 150.5 0.0 8e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP11671.1 - 3.5e-06 26.6 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP11671.1 - 9.8e-06 25.1 0.4 2.1e-05 24.0 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP11671.1 - 2.3e-05 23.5 1.7 3.9e-05 22.8 1.7 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP11671.1 - 3.8e-05 23.4 0.9 6.6e-05 22.6 0.9 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP11671.1 - 0.18 11.7 0.1 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP11671.1 - 0.26 10.9 1.3 2.1 7.9 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Fib_alpha PF08702.10 KFP11672.1 - 2.7e-05 24.4 41.1 0.2 11.8 5.9 5.2 1 1 2 5 5 5 4 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KFP11672.1 - 0.00044 19.2 46.7 0.032 13.1 7.8 4.5 1 1 3 5 5 5 5 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KFP11672.1 - 0.0013 18.9 16.6 0.0013 18.9 16.6 4.6 2 1 2 4 4 4 1 Tropomyosin like Baculo_PEP_C PF04513.12 KFP11672.1 - 0.0015 18.6 26.9 0.53 10.3 1.0 5.2 1 1 4 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.13 KFP11672.1 - 0.0048 16.0 4.6 0.0048 16.0 4.6 3.5 1 1 3 4 4 4 1 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 KFP11672.1 - 0.0078 16.3 5.2 0.0078 16.3 5.2 4.9 2 1 3 5 5 5 2 TPR/MLP1/MLP2-like protein HsbA PF12296.8 KFP11672.1 - 0.013 15.9 14.4 3.5 8.1 1.3 5.3 1 1 4 5 5 5 0 Hydrophobic surface binding protein A Tropomyosin PF00261.20 KFP11672.1 - 0.019 14.4 42.6 0.036 13.4 5.4 5.0 2 1 2 4 4 4 0 Tropomyosin Fez1 PF06818.15 KFP11672.1 - 0.019 15.4 38.4 0.79 10.1 21.0 4.1 1 1 2 3 3 3 0 Fez1 EzrA PF06160.12 KFP11672.1 - 0.029 12.5 41.5 1.2 7.2 25.7 4.6 1 1 2 4 4 4 0 Septation ring formation regulator, EzrA DUF3584 PF12128.8 KFP11672.1 - 0.045 11.3 35.1 0.0039 14.8 19.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.6 KFP11672.1 - 0.059 12.7 44.9 0.62 9.4 11.5 4.7 2 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KFP11672.1 - 0.11 12.6 46.0 0.71 10.0 5.4 6.4 4 2 2 6 6 6 0 BRE1 E3 ubiquitin ligase KxDL PF10241.9 KFP11672.1 - 0.13 12.6 35.9 3.3 8.1 0.1 7.7 2 2 4 8 8 8 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFP11672.1 - 0.14 12.2 42.0 2.8 8.0 0.5 7.4 1 1 6 7 7 7 0 Protein of unknown function (DUF1664) E2R135 PF11570.8 KFP11672.1 - 0.14 12.5 12.2 0.089 13.1 3.1 3.8 3 2 1 4 4 4 0 Coiled-coil receptor-binding R-domain of colicin E2 Laminin_I PF06008.14 KFP11672.1 - 0.16 11.7 38.6 0.49 10.1 7.0 5.2 1 1 1 4 4 4 0 Laminin Domain I TFR_dimer PF04253.15 KFP11672.1 - 0.17 12.0 0.1 0.17 12.0 0.1 4.8 3 1 1 4 4 3 0 Transferrin receptor-like dimerisation domain Atg14 PF10186.9 KFP11672.1 - 0.49 9.4 30.9 0.12 11.4 2.8 4.6 1 1 4 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KFP11672.1 - 0.5 10.4 38.3 0.14 12.2 0.8 5.3 1 1 5 6 6 6 0 Laminin Domain II TMPIT PF07851.13 KFP11672.1 - 0.53 9.5 34.9 0.18 11.0 7.6 4.2 1 1 1 4 4 4 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 KFP11672.1 - 0.85 9.6 52.0 1.4 8.9 0.3 5.4 2 1 3 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cob_adeno_trans PF01923.18 KFP11672.1 - 0.9 9.7 19.2 2 8.5 0.6 4.7 1 1 1 4 4 4 0 Cobalamin adenosyltransferase HrpB7 PF09486.10 KFP11672.1 - 0.91 9.9 16.7 9.4 6.6 0.3 4.8 2 1 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) HMMR_N PF15905.5 KFP11672.1 - 1.2 8.5 47.6 2.2 7.6 4.2 4.4 1 1 4 5 5 5 0 Hyaluronan mediated motility receptor N-terminal PCRF PF03462.18 KFP11672.1 - 1.6 8.6 32.8 1.8 8.4 7.1 4.5 2 1 0 4 4 4 0 PCRF domain FlaC_arch PF05377.11 KFP11672.1 - 2.4 8.6 46.8 2.4 8.6 3.2 9.2 5 2 4 9 9 9 0 Flagella accessory protein C (FlaC) THOC7 PF05615.13 KFP11672.1 - 2.5 8.4 36.4 0.24 11.7 8.2 5.3 1 1 3 5 5 5 0 Tho complex subunit 7 LPP PF04728.13 KFP11672.1 - 2.7 8.5 26.2 12 6.4 0.2 7.5 6 2 1 7 7 7 0 Lipoprotein leucine-zipper DUF16 PF01519.16 KFP11672.1 - 3.7 8.1 41.6 0.044 14.3 2.5 5.7 1 1 2 4 4 3 0 Protein of unknown function DUF16 APG6_N PF17675.1 KFP11672.1 - 4.6 7.8 45.0 15 6.1 0.1 4.7 2 1 1 3 3 3 0 Apg6 coiled-coil region COG2 PF06148.11 KFP11672.1 - 7.6 6.6 40.8 0.43 10.7 3.2 6.0 2 1 4 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.6 KFP11672.1 - 8.2 6.9 41.9 12 6.3 10.2 5.1 2 1 2 5 5 5 0 Domain of unknown function (DUF4200) ADIP PF11559.8 KFP11672.1 - 8.6 6.4 40.1 0.17 11.9 5.5 5.4 1 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding RNA_pol_Rpb2_6 PF00562.28 KFP11673.1 - 3.6e-128 428.0 0.0 1.2e-127 426.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFP11673.1 - 1.3e-54 184.8 0.7 2.2e-54 184.1 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFP11673.1 - 5.9e-35 119.5 0.7 1.7e-34 118.0 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFP11673.1 - 7.2e-28 97.5 1.6 8.2e-28 97.3 0.5 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KFP11673.1 - 5.3e-27 93.9 1.1 1.4e-26 92.5 1.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFP11673.1 - 3.7e-21 75.1 0.0 9.1e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFP11673.1 - 6.5e-10 39.4 3.1 6.5e-10 39.4 3.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 5 RFX_DNA_binding PF02257.15 KFP11674.1 - 1.4e-34 118.5 0.0 4.3e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFP11674.1 - 5.8e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like Ric8 PF10165.9 KFP11675.1 - 3.4e-131 438.5 2.0 3.9e-131 438.2 2.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KFP11675.1 - 0.0044 16.1 0.3 0.0091 15.0 0.3 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal UPF0444 PF15475.6 KFP11676.1 - 3.4e-46 155.4 14.0 3.8e-46 155.3 14.0 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 mTERF PF02536.14 KFP11677.1 - 4.6e-28 98.1 7.6 5.6e-28 97.8 7.6 1.1 1 0 0 1 1 1 1 mTERF K-box PF01486.17 KFP11677.1 - 0.077 13.2 5.6 1.1 9.4 0.0 3.5 4 0 0 4 4 4 0 K-box region RRF_GI PF12614.8 KFP11677.1 - 0.077 13.1 3.3 0.15 12.2 0.4 2.6 2 1 1 3 3 3 0 Ribosome recycling factor FAD_binding_7 PF03441.14 KFP11678.1 - 8.2e-80 267.0 0.4 1.4e-79 266.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFP11678.1 - 1.9e-25 89.8 0.0 3.7e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase LRR_8 PF13855.6 KFP11679.1 - 3.8e-38 129.1 41.5 1.7e-12 46.9 3.3 3.5 1 1 3 4 4 4 4 Leucine rich repeat I-set PF07679.16 KFP11679.1 - 6.2e-15 55.0 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KFP11679.1 - 2.2e-13 50.1 22.9 5.6e-06 26.6 1.6 4.7 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 KFP11679.1 - 2.8e-13 50.3 0.1 1.1e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain LRR_5 PF13306.6 KFP11679.1 - 1.5e-11 44.4 0.0 1.3e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) ig PF00047.25 KFP11679.1 - 8e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP11679.1 - 1.6e-07 31.5 0.2 1.2e-06 28.8 0.0 2.5 2 1 0 2 2 2 1 Fibronectin type III domain LRR_9 PF14580.6 KFP11679.1 - 9.4e-07 28.5 5.9 0.0002 20.9 0.6 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 KFP11679.1 - 8.7e-06 26.0 0.2 5.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KFP11679.1 - 0.00019 21.5 17.1 1.9 9.3 0.7 6.8 6 1 1 7 7 6 2 Leucine Rich Repeat Ig_C17orf99 PF17736.1 KFP11679.1 - 0.0013 18.8 0.1 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 C17orf99 Ig domain LRRCT PF01463.24 KFP11679.1 - 0.038 14.5 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain zf-CXXC PF02008.20 KFP11681.1 - 1.6e-07 31.2 23.5 2.5e-07 30.6 23.5 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain TCO89 PF10452.9 KFP11681.1 - 0.032 13.2 5.8 0.047 12.7 5.8 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 Striatin PF08232.12 KFP11681.1 - 0.071 13.7 1.4 0.12 13.0 1.4 1.3 1 0 0 1 1 1 0 Striatin family QueC PF06508.13 KFP11681.1 - 2.9 7.3 10.9 1.7 8.1 0.8 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC Sec7 PF01369.20 KFP11682.1 - 7.1e-43 146.4 0.6 1.5e-42 145.4 0.1 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KFP11682.1 - 3.7e-38 130.6 3.7 8.6e-38 129.4 0.1 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KFP11682.1 - 9e-14 51.9 0.1 2.2e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 PH domain COBRA1 PF06209.13 KFP11682.1 - 0.0093 14.9 0.7 0.049 12.5 0.0 2.0 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) PH_11 PF15413.6 KFP11682.1 - 0.024 15.1 0.2 0.1 13.0 0.2 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain NADPH_Ox PF08414.10 KFP11682.1 - 0.082 13.2 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase PurA PF04845.13 KFP11683.1 - 1e-18 67.5 0.1 1.1e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein EGF PF00008.27 KFP11685.1 - 7.5e-06 26.1 5.0 1.5e-05 25.1 5.0 1.6 1 0 0 1 1 1 1 EGF-like domain Ninjurin PF04923.12 KFP11685.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Ninjurin CD34_antigen PF06365.12 KFP11685.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family EGF_2 PF07974.13 KFP11685.1 - 3.3 8.2 8.3 0.61 10.5 4.6 1.8 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 KFP11685.1 - 4.2 8.2 8.0 2 9.2 4.2 2.5 2 1 0 2 2 2 0 Human growth factor-like EGF PID PF00640.23 KFP11686.1 - 4.7e-18 65.6 0.0 5.6e-09 36.2 0.0 2.6 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.26 KFP11686.1 - 9.7e-07 28.8 4.9 2.5e-06 27.4 4.9 1.8 1 0 0 1 1 1 1 WW domain DUF4462 PF14692.6 KFP11687.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) AA_permease_2 PF13520.6 KFP11688.1 - 3.6e-48 164.5 39.8 1.6e-39 136.0 25.6 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFP11688.1 - 7.8e-23 80.8 26.6 7.8e-23 80.8 26.6 2.2 2 1 0 2 2 2 2 Amino acid permease DoxX_2 PF13564.6 KFP11688.1 - 0.28 11.3 6.9 1.3 9.2 0.2 3.8 2 1 1 3 3 3 0 DoxX-like family Exo_endo_phos PF03372.23 KFP11689.1 - 5e-23 81.8 0.0 6.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFP11689.1 - 0.0025 17.7 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase E3_UbLigase_EDD PF11547.8 KFP11689.1 - 0.088 12.5 0.7 2.5 7.9 0.1 2.7 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD PKD PF00801.20 KFP11695.1 - 9.9e-07 28.5 0.9 0.097 12.5 0.0 3.6 4 0 0 4 4 4 2 PKD domain Pentaxin PF00354.17 KFP11697.1 - 4e-33 114.8 0.0 5.6e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP11697.1 - 3.8e-14 53.1 0.0 5.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SlyX PF04102.12 KFP11697.1 - 0.00059 20.4 8.4 0.27 11.9 0.1 3.9 3 1 0 3 3 3 2 SlyX LIAS_N PF16881.5 KFP11697.1 - 0.011 16.2 0.2 0.038 14.4 0.1 2.0 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Sun2_CC2 PF18580.1 KFP11697.1 - 0.02 15.1 2.9 0.14 12.4 0.9 2.5 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 GOLGA2L5 PF15070.6 KFP11697.1 - 0.06 12.0 7.1 0.079 11.6 7.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Apolipoprotein PF01442.18 KFP11697.1 - 0.06 13.2 9.3 0.28 11.0 9.4 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain bZIP_1 PF00170.21 KFP11697.1 - 0.074 13.2 6.1 1.2 9.2 1.2 3.2 2 1 1 3 3 3 0 bZIP transcription factor T3SS_basalb_I PF17001.5 KFP11697.1 - 0.076 13.6 0.6 0.2 12.3 0.2 1.9 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Laminin_G_2 PF02210.24 KFP11697.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain DUF668 PF05003.12 KFP11697.1 - 0.17 12.4 0.2 0.4 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) JIP_LZII PF16471.5 KFP11697.1 - 0.3 11.3 8.6 0.71 10.1 4.1 2.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II K-box PF01486.17 KFP11697.1 - 0.45 10.7 6.5 1.1 9.5 6.5 1.6 1 0 0 1 1 1 0 K-box region DUF1664 PF07889.12 KFP11697.1 - 0.49 10.5 2.4 37 4.4 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFP11697.1 - 0.53 10.3 2.4 1.9 8.5 2.4 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.19 KFP11697.1 - 0.66 9.6 4.5 1.8 8.2 4.5 1.8 1 1 0 1 1 1 0 GrpE CorA PF01544.18 KFP11697.1 - 1.2 8.4 5.1 2.1 7.6 5.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC_tran_CTD PF16326.5 KFP11697.1 - 1.2 9.4 10.8 0.4 11.0 0.8 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain PspB PF06667.12 KFP11697.1 - 2.5 8.2 4.6 0.81 9.8 0.1 2.3 2 1 0 2 2 2 0 Phage shock protein B CLZ PF16526.5 KFP11697.1 - 2.6 8.5 8.3 2.6 8.5 0.0 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CCDC-167 PF15188.6 KFP11697.1 - 7.3 7.0 8.1 44 4.5 8.0 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pox_A_type_inc PF04508.12 KFP11697.1 - 9.3 6.3 16.6 6.5 6.8 0.3 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat IMD PF08397.11 KFP11698.1 - 3.7e-62 209.6 4.2 4.7e-62 209.2 4.2 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.6 KFP11698.1 - 3.8e-11 42.7 0.0 7.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP11698.1 - 1.9e-07 30.7 0.0 3.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP11698.1 - 7.5e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR_3 PF16746.5 KFP11698.1 - 0.0011 18.7 9.7 0.0047 16.7 9.7 1.8 1 1 0 1 1 1 1 BAR domain of APPL family Rhabdo_M1 PF03342.13 KFP11698.1 - 0.047 13.1 1.1 0.12 11.8 0.7 1.8 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) OrfB_IS605 PF01385.19 KFP11698.1 - 0.35 11.1 0.1 0.35 11.1 0.1 2.5 1 1 1 2 2 2 0 Probable transposase LMBR1 PF04791.16 KFP11698.1 - 0.92 8.3 2.5 1.2 7.9 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2367 PF10164.9 KFP11699.1 - 1.2e-37 128.5 6.0 1.3e-37 128.5 6.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF4126 PF13548.6 KFP11699.1 - 0.028 14.1 1.2 0.031 14.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) zf-RING_4 PF14570.6 KFP11699.1 - 0.035 13.9 1.0 4.8 7.0 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 KFP11699.1 - 0.12 11.9 0.2 0.12 11.9 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KFP11699.1 - 0.13 12.0 3.3 7.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_Rg PF17915.1 KFP11699.1 - 0.18 11.2 4.5 1.1 8.7 0.3 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger DUF1936 PF09151.10 KFP11699.1 - 0.45 10.5 0.4 0.45 10.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Hyd_WA PF06462.12 KFP11700.1 - 5.4e-66 218.2 59.3 1.2e-11 44.3 3.2 10.7 12 0 0 12 12 12 8 Propeller Pex24p PF06398.11 KFP11700.1 - 7e-22 77.9 20.2 3.7e-12 45.9 4.1 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin PH PF00169.29 KFP11700.1 - 0.0027 18.2 0.4 0.0075 16.8 0.4 1.8 1 0 0 1 1 1 1 PH domain HLH PF00010.26 KFP11701.1 - 2.9e-17 62.3 4.1 6.9e-17 61.1 4.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RepB PF07506.11 KFP11701.1 - 0.084 13.0 2.5 0.11 12.5 2.5 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein Pkinase_Tyr PF07714.17 KFP11702.1 - 8.4e-55 185.8 0.0 1.2e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP11702.1 - 5.8e-27 94.7 0.0 9.9e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 KFP11703.1 - 3.5e-13 48.1 2.1 6.6e-06 25.3 0.6 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP11703.1 - 9.3e-13 48.4 0.1 1.3e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP11703.1 - 2.7e-12 45.5 0.6 4.8e-06 26.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP11703.1 - 1.7e-11 43.1 3.2 2.8e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP11703.1 - 3e-06 27.0 0.5 4.1e-05 23.3 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP11703.1 - 0.0064 16.8 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Skp1 PF01466.19 KFP11703.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Skp1 family, dimerisation domain RuvC PF02075.17 KFP11703.1 - 0.031 14.2 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC EFhand_Ca_insen PF08726.10 KFP11703.1 - 0.13 12.4 0.3 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 KFP11704.1 - 2e-05 24.2 0.2 5.3e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFP11704.1 - 7.2e-05 23.2 0.0 7.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP11704.1 - 8.8e-05 21.8 0.5 0.00015 21.1 0.5 1.4 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KFP11704.1 - 0.004 16.6 0.7 0.0063 16.0 0.7 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFP11705.1 - 9.1e-15 54.9 0.6 1.3e-14 54.4 0.6 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP11705.1 - 3e-14 51.4 2.5 5.8e-07 28.6 0.7 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP11705.1 - 3.3e-12 45.3 2.3 4.7e-06 26.1 0.7 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP11705.1 - 4.2e-11 41.8 2.3 1.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP11705.1 - 2.1e-06 27.5 0.1 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP11705.1 - 0.037 14.3 0.1 0.064 13.6 0.1 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.6 KFP11705.1 - 0.04 14.3 0.0 8 7.0 0.0 2.1 1 1 1 2 2 2 0 Toprim-like EF-hand_10 PF14788.6 KFP11705.1 - 0.23 11.3 2.7 0.58 10.1 0.6 2.4 2 1 0 2 2 2 0 EF hand DUF1712 PF08217.11 KFP11706.1 - 2.4e-95 320.3 8.2 1.4e-85 288.0 1.3 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) MORN PF02493.20 KFP11707.1 - 4.5e-18 64.0 32.8 2.6e-07 30.1 1.0 5.3 5 1 0 5 5 5 5 MORN repeat Tudor_2 PF18104.1 KFP11707.1 - 0.015 15.0 0.2 3.3 7.5 0.1 2.8 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain MutL_C PF08676.11 KFP11708.1 - 1.2e-31 109.5 0.0 3.5e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFP11708.1 - 6.8e-24 83.8 0.5 4.9e-23 81.1 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFP11708.1 - 7.1e-12 45.3 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFP11708.1 - 6.9e-06 26.5 0.2 2.1e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin_16 PF18569.1 KFP11709.1 - 3.5e-36 123.2 0.3 6e-36 122.5 0.3 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain GST_C PF00043.25 KFP11709.1 - 1e-07 32.1 0.1 2.2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP11709.1 - 2.2e-06 27.6 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP11709.1 - 9.6e-06 25.7 0.0 5.6e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFP11709.1 - 0.00087 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 KFP11710.1 - 4.2e-46 157.5 0.7 5.5e-29 101.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11710.1 - 4.6e-25 88.4 0.5 1e-17 64.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SlyX PF04102.12 KFP11710.1 - 0.0098 16.5 2.1 0.029 15.0 2.1 1.8 1 0 0 1 1 1 1 SlyX DUF641 PF04859.12 KFP11710.1 - 0.01 16.1 1.5 0.01 16.1 1.5 2.2 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Kdo PF06293.14 KFP11710.1 - 0.028 13.8 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family P4Ha_N PF08336.11 KFP11710.1 - 0.031 14.3 1.3 0.074 13.1 1.3 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FTA2 PF13095.6 KFP11710.1 - 0.039 13.6 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF16 PF01519.16 KFP11710.1 - 0.059 13.9 0.8 0.059 13.9 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 Csm1_N PF18504.1 KFP11710.1 - 0.22 11.9 2.9 0.64 10.4 2.9 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain APH PF01636.23 KFP11710.1 - 1.1 9.1 4.2 0.28 11.1 0.3 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family DivIC PF04977.15 KFP11710.1 - 1.4 8.8 5.6 1.1 9.1 3.5 1.9 2 0 0 2 2 2 0 Septum formation initiator UCH PF00443.29 KFP11711.1 - 1e-48 166.1 1.5 1e-48 166.1 1.5 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP11711.1 - 5.1e-19 69.0 4.1 5.1e-19 69.0 4.1 3.6 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Sec7 PF01369.20 KFP11712.1 - 1.4e-73 246.5 0.2 1.8e-73 246.1 0.2 1.1 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KFP11712.1 - 1.8e-28 99.1 0.1 3.7e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP11712.1 - 4e-05 24.0 1.9 7e-05 23.2 0.2 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFP11712.1 - 0.022 14.8 0.0 0.085 13.0 0.0 2.1 1 1 0 1 1 1 0 PH domain PH_8 PF15409.6 KFP11712.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain GPS2_interact PF15784.5 KFP11712.1 - 0.54 10.7 4.5 0.58 10.6 3.0 1.8 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Ras PF00071.22 KFP11714.1 - 1.9e-50 170.6 0.0 2.2e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11714.1 - 6.3e-19 68.4 0.0 8.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11714.1 - 2.5e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP11714.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CagD PF16567.5 KFP11714.1 - 0.029 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity island component CagD Lipase_3 PF01764.25 KFP11715.1 - 2.4e-10 40.5 0.0 7.7e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Frag1 PF10277.9 KFP11715.1 - 0.067 12.7 4.1 0.13 11.8 4.1 1.4 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Abhydrolase_6 PF12697.7 KFP11715.1 - 0.12 12.9 0.0 0.5 10.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family ER_lumen_recept PF00810.18 KFP11716.1 - 4e-54 183.4 9.1 4e-54 183.4 9.1 1.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFP11716.1 - 0.031 14.1 1.3 0.031 14.1 1.3 2.8 3 2 2 5 5 5 0 PQ loop repeat Mesothelin PF06060.12 KFP11717.1 - 1.6e-16 59.7 1.0 2.1e-16 59.3 0.1 1.6 2 0 0 2 2 2 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Ribosomal_L27_C PF18471.1 KFP11717.1 - 0.042 13.3 1.4 2.4 7.5 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L27 protein C-terminal domain PYRIN PF02758.16 KFP11717.1 - 0.06 13.5 0.2 3.7 7.8 0.0 3.7 2 1 1 3 3 3 0 PAAD/DAPIN/Pyrin domain NuA4 PF09340.10 KFP11717.1 - 0.13 12.1 0.4 0.66 9.9 0.1 2.3 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DREV PF05219.12 KFP11718.1 - 1.1e-130 434.4 0.1 1.3e-130 434.3 0.1 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KFP11718.1 - 2.1e-11 43.9 0.0 3.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP11718.1 - 9.5e-09 35.9 0.0 1.5e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP11718.1 - 7.5e-06 26.5 0.0 3e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP11718.1 - 4.8e-05 24.0 0.0 0.00017 22.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP11718.1 - 0.1 12.1 0.0 3.2 7.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFP11718.1 - 0.11 12.3 0.0 0.44 10.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain V-set PF07686.17 KFP11719.1 - 2.9e-05 24.2 0.4 0.0001 22.4 0.4 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP11719.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP11719.1 - 0.043 14.4 0.1 0.095 13.3 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin domain MFS_2 PF13347.6 KFP11720.1 - 7e-36 123.7 21.8 8.9e-36 123.4 21.8 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein ZapB PF06005.12 KFP11721.1 - 0.0074 16.7 2.0 0.0074 16.7 2.0 6.2 4 3 2 6 6 6 2 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 KFP11721.1 - 0.016 15.4 17.3 0.016 15.4 17.3 3.9 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 KFP11721.1 - 0.02 14.7 0.6 0.02 14.7 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF724) DUF4618 PF15397.6 KFP11721.1 - 0.16 11.4 36.6 0.078 12.4 14.5 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) ATG16 PF08614.11 KFP11721.1 - 0.26 11.5 38.3 0.27 11.4 5.3 3.6 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) APC_N_CC PF16689.5 KFP11721.1 - 0.27 11.3 12.4 2.1 8.5 0.3 5.0 4 1 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain GIT_CC PF16559.5 KFP11721.1 - 0.33 10.9 22.9 1.1 9.2 1.0 4.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 KFP11721.1 - 1.4 9.0 43.0 4.4 7.4 15.9 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_IE-1 PF05290.11 KFP11721.1 - 4.7 7.2 9.3 9.4 6.2 0.7 3.3 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) NPV_P10 PF05531.12 KFP11721.1 - 5.3 7.6 14.4 2 8.9 0.1 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KFP11721.1 - 7.8 4.9 5.8 14 4.1 5.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Taxilin PF09728.9 KFP11721.1 - 9.8 5.2 42.5 0.27 10.4 13.5 3.6 3 1 0 3 3 3 0 Myosin-like coiled-coil protein Sin_N PF04801.13 KFP11722.1 - 4.8e-151 503.8 2.6 4.8e-151 503.8 2.6 2.4 3 0 0 3 3 3 1 Sin-like protein conserved region ATG13 PF10033.9 KFP11722.1 - 0.43 10.2 2.8 0.16 11.6 0.2 1.6 2 0 0 2 2 2 0 Autophagy-related protein 13 Alpha_kinase PF02816.18 KFP11723.1 - 2.6e-60 203.7 0.2 4.2e-60 203.0 0.2 1.4 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 KFP11723.1 - 4e-06 27.3 7.0 2 9.2 0.0 5.1 5 0 0 5 5 5 3 Sel1 repeat 3Beta_HSD PF01073.19 KFP11725.1 - 1.5e-66 224.3 0.0 1.9e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP11725.1 - 2.9e-26 92.4 0.0 3.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP11725.1 - 4.2e-13 49.4 0.0 1e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFP11725.1 - 3.8e-09 36.1 0.0 5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFP11725.1 - 7.8e-08 31.8 0.6 3.8e-07 29.5 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFP11725.1 - 1.7e-07 31.3 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFP11725.1 - 3.4e-07 29.7 0.0 8.8e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KFP11725.1 - 8.4e-05 22.2 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFP11725.1 - 0.0046 16.4 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase VWA_3 PF13768.6 KFP11726.1 - 5e-55 185.7 0.2 9.1e-21 74.4 0.0 3.6 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 KFP11726.1 - 3.6e-15 56.6 0.0 2e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP11726.1 - 2.5e-10 40.9 0.0 0.00018 22.1 0.0 3.7 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP11726.1 - 0.0036 16.7 0.1 0.079 12.3 0.0 2.4 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Atthog PF18800.1 KFP11728.1 - 3.2e-62 208.6 4.1 3.5e-62 208.4 4.1 1.0 1 0 0 1 1 1 1 Attenuator of Hedgehog 7tm_3 PF00003.22 KFP11728.1 - 5.1e-05 23.1 4.7 5.6e-05 23.0 4.7 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cyt_bd_oxida_I PF01654.17 KFP11728.1 - 0.00017 20.3 4.0 0.00021 20.1 4.0 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I LtrA PF06772.11 KFP11728.1 - 0.0015 17.8 0.5 0.0018 17.6 0.5 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF423 PF04241.15 KFP11728.1 - 0.057 13.6 0.9 0.057 13.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF998 PF06197.13 KFP11728.1 - 0.073 12.7 7.1 0.2 11.2 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) L_HMGIC_fpl PF10242.9 KFP11728.1 - 0.094 12.9 5.8 0.15 12.2 5.5 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein TctB PF07331.11 KFP11728.1 - 0.28 11.5 10.9 0.95 9.7 10.9 1.8 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3784 PF12650.7 KFP11728.1 - 0.9 9.8 11.7 2.6 8.3 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2721 PF11026.8 KFP11728.1 - 1.5 8.7 10.3 1.7 8.6 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF456 PF04306.13 KFP11728.1 - 2.4 8.4 11.4 16 5.7 11.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Peptidase_M16 PF00675.20 KFP11729.1 - 6.4e-32 110.6 0.0 1.1e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP11729.1 - 1.5e-23 83.7 0.1 7.9e-23 81.4 0.0 2.2 3 0 0 3 3 3 1 Peptidase M16 inactive domain OCD_Mu_crystall PF02423.15 KFP11730.1 - 4.6e-92 308.3 0.3 5.1e-92 308.2 0.3 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFP11730.1 - 3.2e-09 37.0 0.0 5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KFP11730.1 - 0.00017 21.8 0.7 0.0023 18.1 0.4 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFP11730.1 - 0.00029 21.3 0.0 0.00076 20.0 0.0 1.8 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OTCace PF00185.24 KFP11730.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ank_2 PF12796.7 KFP11731.1 - 3.8e-16 59.5 0.3 7.1e-15 55.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP11731.1 - 7.6e-16 58.0 4.2 4.7e-07 29.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP11731.1 - 1.6e-14 54.0 0.8 1.4e-05 25.5 0.1 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP11731.1 - 4e-10 39.7 1.3 5.4e-08 32.9 0.4 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFP11731.1 - 2.1e-09 36.8 0.4 6.1e-05 23.1 0.2 3.9 3 0 0 3 3 3 1 Ankyrin repeat SAM_1 PF00536.30 KFP11731.1 - 5.4e-07 30.0 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP11731.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_S18 PF01084.20 KFP11731.1 - 0.019 15.2 0.7 0.054 13.7 0.3 1.9 2 0 0 2 2 2 0 Ribosomal protein S18 Presenilin PF01080.17 KFP11731.1 - 7.1 5.3 6.6 9.4 4.9 6.6 1.2 1 0 0 1 1 1 0 Presenilin Zona_pellucida PF00100.23 KFP11732.1 - 1.2e-48 166.2 0.1 2.7e-47 161.8 0.0 2.4 2 0 0 2 2 2 2 Zona pellucida-like domain Promethin PF16015.5 KFP11733.1 - 3.3e-23 81.6 12.7 3.9e-23 81.4 12.7 1.1 1 0 0 1 1 1 1 Promethin CcmH PF03918.14 KFP11733.1 - 0.086 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Complex1_LYR PF05347.15 KFP11734.1 - 1.1e-11 44.6 0.1 1.7e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP11734.1 - 0.06 14.1 0.3 0.082 13.7 0.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like DUF2312 PF10073.9 KFP11734.1 - 0.18 11.5 2.8 0.27 10.9 2.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Cullin_binding PF03556.15 KFP11735.1 - 5.2e-33 114.0 0.2 9e-33 113.3 0.2 1.3 1 0 0 1 1 1 1 Cullin binding RRM_1 PF00076.22 KFP11736.1 - 1.5e-19 69.5 0.0 5.9e-11 42.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KFP11736.1 - 1.5e-06 28.8 0.0 5.3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Exonuclease TMF_DNA_bd PF12329.8 KFP11736.1 - 1.4 9.0 8.7 0.049 13.6 2.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RNase_T PF00929.24 KFP11737.1 - 8e-25 88.3 0.0 1.1e-24 87.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease HSDR_N PF04313.14 KFP11737.1 - 0.069 13.1 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) AMP-binding PF00501.28 KFP11738.1 - 1.2e-82 277.7 0.0 1.5e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP11738.1 - 7.5e-24 84.5 1.4 1.4e-23 83.6 1.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_9 PF14604.6 KFP11738.1 - 0.29 11.0 1.0 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 Variant SH3 domain SRI PF08236.11 KFP11738.1 - 0.65 10.2 2.6 0.51 10.5 0.7 1.9 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain THUMP PF02926.17 KFP11739.1 - 3.4e-24 85.6 0.6 6.4e-24 84.7 0.4 1.5 1 1 0 1 1 1 1 THUMP domain AMP-binding PF00501.28 KFP11740.1 - 5.1e-77 259.3 0.0 6.2e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP11740.1 - 3e-23 82.6 0.5 5.5e-23 81.7 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thioredoxin_6 PF13848.6 KFP11741.1 - 3.6e-35 121.5 4.4 3.6e-32 111.8 1.8 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFP11741.1 - 3.5e-12 46.2 0.2 6.5e-09 35.7 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin OST3_OST6 PF04756.13 KFP11741.1 - 4e-09 36.2 0.4 2e-05 24.1 0.1 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFP11741.1 - 0.024 15.0 0.2 6.2 7.2 0.0 3.7 3 1 0 4 4 4 0 Thioredoxin-like 7tm_1 PF00001.21 KFP11743.1 - 4e-23 82.1 28.6 5.3e-23 81.7 28.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP11743.1 - 5.5e-09 35.7 29.0 6.8e-05 22.3 13.0 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFP11743.1 - 7.7e-08 32.3 28.2 7.7e-08 32.3 28.2 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SMAP PF15477.6 KFP11744.1 - 2e-13 51.1 1.1 2e-13 51.1 1.1 2.4 2 1 0 2 2 2 1 Small acidic protein family INTS5_N PF14837.6 KFP11745.1 - 0.031 13.9 0.3 2.2 7.8 0.0 3.1 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus CytochromB561_N PF09786.9 KFP11745.1 - 0.22 10.5 4.5 0.39 9.7 4.5 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF4698 PF15769.5 KFP11745.1 - 0.3 10.1 3.8 0.61 9.1 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) HSCB_C PF07743.13 KFP11745.1 - 0.53 10.8 5.2 0.15 12.6 1.4 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain CALM_bind PF16025.5 KFP11746.1 - 1.2e-18 67.4 0.7 1.2e-18 67.4 0.7 4.6 4 1 1 5 5 5 2 Calcium-dependent calmodulin binding DUF2797 PF10977.8 KFP11746.1 - 0.15 12.0 4.7 0.056 13.3 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) GDPD PF03009.17 KFP11750.1 - 1.6e-22 80.5 0.0 3.8e-22 79.3 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TMC PF07810.13 KFP11751.1 - 5.7e-39 133.1 1.4 5.7e-39 133.1 1.4 3.3 3 1 0 3 3 3 1 TMC domain TMC PF07810.13 KFP11753.1 - 4.9e-47 159.1 2.0 4.9e-47 159.1 2.0 3.4 4 0 0 4 4 4 1 TMC domain COQ7 PF03232.13 KFP11754.1 - 1.1e-71 240.1 0.0 1.2e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KFP11754.1 - 0.00033 21.0 0.1 0.01 16.3 0.1 2.1 1 1 1 2 2 2 2 Rubrerythrin Muraidase PF11860.8 KFP11754.1 - 0.056 13.7 0.1 0.96 9.6 0.0 2.2 2 1 0 2 2 2 0 N-acetylmuramidase Ferritin_2 PF13668.6 KFP11754.1 - 0.077 13.2 0.2 15 5.8 0.0 2.2 1 1 1 2 2 2 0 Ferritin-like domain C2 PF00168.30 KFP11755.1 - 1.1e-42 144.5 0.1 1.4e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 C2 domain Lectin_C PF00059.21 KFP11757.1 - 1.6e-18 67.4 0.2 2e-18 67.1 0.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain Reticulon PF02453.17 KFP11758.1 - 0.0017 18.4 4.2 0.0024 17.9 4.2 1.1 1 0 0 1 1 1 1 Reticulon BCL_N PF04714.13 KFP11758.1 - 0.44 10.6 0.1 0.44 10.6 0.1 2.5 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Ribosomal_S8 PF00410.19 KFP11759.1 - 1.9e-22 79.6 0.0 2.6e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 NAC PF01849.18 KFP11761.1 - 1.8e-23 82.2 0.3 4.1e-23 81.1 0.2 1.7 2 0 0 2 2 2 1 NAC domain Ribosomal_L30 PF00327.20 KFP11761.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e CCM2_C PF16545.5 KFP11762.1 - 2.1e-47 159.8 0.3 3.6e-47 159.0 0.3 1.4 1 0 0 1 1 1 1 Cerebral cavernous malformation protein, harmonin-homology PID PF00640.23 KFP11762.1 - 0.0056 16.7 0.0 0.022 14.8 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF1722 PF08349.11 KFP11762.1 - 0.029 14.6 0.1 0.079 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Inv-AAD PF18785.1 KFP11762.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase HTH_48 PF17906.1 KFP11762.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase ELP6 PF09807.9 KFP11763.1 - 6.1e-103 343.6 0.6 6.8e-103 343.5 0.6 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 Ras PF00071.22 KFP11764.1 - 4e-50 169.6 0.0 4e-50 169.6 0.0 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFP11764.1 - 2.8e-30 105.0 0.0 6.8e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11764.1 - 7e-15 54.9 1.2 8.9e-15 54.6 0.0 1.8 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP11764.1 - 1.5e-08 34.7 0.0 5.6e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP11764.1 - 0.0047 16.5 0.0 0.0047 16.5 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KFP11764.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.4 4 1 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 KFP11764.1 - 0.5 10.3 4.2 6.7 6.6 0.0 3.4 3 1 2 5 5 5 0 RsgA GTPase DUF2514 PF10721.9 KFP11764.1 - 1.1 9.3 8.0 3.1 7.8 8.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TTKRSYEDQ PF10212.9 KFP11764.1 - 1.6 7.6 22.5 0.59 9.1 19.4 1.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein GIT_CC PF16559.5 KFP11764.1 - 6 6.8 16.1 7.5 6.5 0.2 4.1 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor FUSC-like PF12805.7 KFP11764.1 - 7.7 5.5 9.2 0.15 11.1 1.9 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS ECH_2 PF16113.5 KFP11764.1 - 9.3 5.6 9.2 16 4.9 9.2 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase FERM_M PF00373.18 KFP11765.1 - 4.6e-19 69.0 0.3 1.1e-18 67.8 0.0 1.7 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFP11765.1 - 7.6e-17 61.5 0.5 1.5e-16 60.6 0.5 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFP11765.1 - 3.6e-14 52.6 2.2 7.3e-14 51.6 2.2 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) Kinesin PF00225.23 KFP11767.1 - 1.7e-101 339.5 0.0 1.7e-101 339.5 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP11767.1 - 5.7e-18 65.3 0.0 3e-15 56.5 0.0 2.9 2 0 0 2 2 2 2 Microtubule binding PIN_12 PF16289.5 KFP11767.1 - 0.61 10.6 9.3 1.3 9.5 8.1 2.2 2 0 0 2 2 2 0 PIN domain DUF4924 PF16271.5 KFP11767.1 - 0.62 10.1 11.9 1.4 8.9 11.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) CARM1 PF11531.8 KFP11767.1 - 1.4 9.1 4.0 1.2 9.3 0.1 2.8 3 0 0 3 3 3 0 Coactivator-associated arginine methyltransferase 1 N terminal Glyco_transf_7C PF02709.14 KFP11768.1 - 3.9e-26 90.5 0.2 7.3e-26 89.6 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KFP11768.1 - 1.8e-21 76.2 0.1 2.8e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KFP11768.1 - 0.051 13.0 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Lectin_leg-like PF03388.13 KFP11769.1 - 1.5e-91 305.9 0.0 1.8e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFP11769.1 - 1.7e-07 31.5 0.0 2.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin UL42 PF17638.2 KFP11769.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 HCMV UL42 Arf PF00025.21 KFP11770.1 - 2.8e-67 225.5 0.0 3.2e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP11770.1 - 7.8e-14 51.9 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP11770.1 - 3e-13 49.6 0.0 3.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFP11770.1 - 7.2e-13 48.4 0.0 8.4e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP11770.1 - 3.6e-09 36.3 0.0 4.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP11770.1 - 3.6e-09 36.7 0.0 5.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFP11770.1 - 4.6e-09 35.9 0.0 3.1e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 KFP11770.1 - 1.7e-05 24.4 0.0 0.0022 17.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KFP11770.1 - 0.0029 18.2 0.0 0.0048 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFP11770.1 - 0.0052 16.7 0.1 2.1 8.2 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFP11770.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KFP11770.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KFP11770.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFP11770.1 - 0.027 14.0 0.0 7.8 6.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFP11770.1 - 0.13 12.2 0.1 0.23 11.4 0.0 1.4 1 1 0 1 1 1 0 NTPase ABC_tran PF00005.27 KFP11770.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFP11770.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KFP11770.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.25 KFP11771.1 - 2.9e-68 230.1 0.0 4.4e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11771.1 - 2.2e-35 122.2 0.0 3.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP11771.1 - 1.2e-20 74.0 0.5 3.2e-20 72.6 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 KFP11771.1 - 2.6e-05 23.2 0.0 5.1e-05 22.2 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFP11771.1 - 0.0001 21.8 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HTH_51 PF18558.1 KFP11771.1 - 0.099 12.5 0.1 0.64 9.9 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Cofilin_ADF PF00241.20 KFP11772.1 - 2.6e-10 40.1 0.0 5.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Spem1 PF15670.5 KFP11772.1 - 9.3 5.7 8.6 14 5.1 8.6 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 DEAD PF00270.29 KFP11773.1 - 1.7e-44 151.7 0.0 7.8e-44 149.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP11773.1 - 3.9e-32 110.9 0.0 3.8e-30 104.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 KFP11773.1 - 0.0013 18.7 1.5 0.0025 17.8 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle ResIII PF04851.15 KFP11773.1 - 0.016 15.2 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KFP11773.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain UTP25 PF06862.12 KFP11773.1 - 0.11 11.2 0.0 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KFP11773.1 - 0.23 10.8 2.0 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KFP11773.1 - 0.27 10.4 0.0 0.27 10.4 0.0 2.2 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase PRELI PF04707.14 KFP11776.1 - 1.6e-33 115.8 0.1 2.5e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 PRELI-like family SWIRM-assoc_2 PF16496.5 KFP11777.1 - 2e-151 504.5 20.7 6.5e-151 502.9 20.7 1.7 1 1 0 1 1 1 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KFP11777.1 - 2.1e-31 108.1 0.1 4.5e-31 107.0 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_3 PF16498.5 KFP11777.1 - 2.5e-31 107.7 1.3 5.6e-31 106.6 1.3 1.7 1 0 0 1 1 1 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 KFP11777.1 - 9.7e-13 48.1 0.2 2e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP11777.1 - 8.7e-08 32.3 0.0 3.1e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Chromo PF00385.24 KFP11777.1 - 0.043 13.7 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2618 PF10940.8 KFP11777.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) CD99L2 PF12301.8 KFP11777.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.6 2 1 0 2 2 2 0 CD99 antigen like protein 2 DUF4462 PF14692.6 KFP11778.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Arb2 PF09757.9 KFP11779.1 - 1.5e-09 37.3 1.5 9.2e-07 28.2 1.5 2.2 1 1 0 1 1 1 1 Arb2 domain Hydrolase_4 PF12146.8 KFP11779.1 - 0.00053 19.3 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 WGG PF10273.9 KFP11779.1 - 0.0011 19.6 0.0 0.82 10.4 0.0 2.6 2 0 0 2 2 2 2 Pre-rRNA-processing protein TSR2 Ser_hydrolase PF06821.13 KFP11779.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_6 PF12697.7 KFP11779.1 - 0.21 12.1 0.0 1.1 9.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4495 PF14906.6 KFP11780.1 - 3.3e-140 466.6 16.2 3.3e-140 466.6 16.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4495) HAD_SAK_1 PF10307.9 KFP11780.1 - 0.039 13.8 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins RTT107_BRCT_5 PF16770.5 KFP11782.1 - 1.6e-09 37.5 0.1 2.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KFP11782.1 - 0.0051 17.2 0.1 0.15 12.5 0.1 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFP11782.1 - 0.011 16.0 0.0 3.6 7.9 0.0 2.2 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 KFP11782.1 - 0.11 12.9 0.1 2.3 8.7 0.1 2.2 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Ank_2 PF12796.7 KFP11783.1 - 1e-18 67.7 0.1 2e-14 53.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP11783.1 - 7.3e-17 59.8 0.1 4.1e-05 23.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFP11783.1 - 4.8e-15 55.7 1.0 3.6e-07 30.6 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP11783.1 - 2.6e-14 53.1 0.1 3.1e-06 27.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP11783.1 - 3.9e-14 52.4 0.2 0.0011 19.3 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat ParcG PF10274.9 KFP11783.1 - 0.042 14.0 0.1 0.7 10.0 0.0 2.7 3 0 0 3 3 3 0 Parkin co-regulated protein C2 PF00168.30 KFP11784.1 - 1.4e-68 227.7 0.1 1.9e-25 89.1 0.0 3.3 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.10 KFP11784.1 - 7e-08 32.4 4.6 2.7e-07 30.5 0.1 2.4 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.11 KFP11784.1 - 2.3e-05 23.6 2.2 4.2e-05 22.7 2.2 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CEP76-C2 PF15627.6 KFP11784.1 - 0.00071 19.2 0.0 0.15 11.6 0.0 3.0 3 0 0 3 3 3 1 CEP76 C2 domain DUF639 PF04842.12 KFP11784.1 - 0.0068 15.8 1.0 0.02 14.3 1.0 1.6 1 1 0 1 1 1 1 Plant protein of unknown function (DUF639) 2OG-FeII_Oxy_4 PF13661.6 KFP11784.1 - 0.0075 16.9 0.1 0.058 14.1 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tom22 PF04281.13 KFP11784.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 E7 PF00527.18 KFP11784.1 - 0.16 12.2 0.3 0.44 10.8 0.3 1.7 1 0 0 1 1 1 0 E7 protein, Early protein TPR_19 PF14559.6 KFP11785.1 - 4.2e-39 132.9 45.4 0.0014 19.1 0.8 16.0 16 1 1 17 17 15 10 Tetratricopeptide repeat TPR_1 PF00515.28 KFP11785.1 - 7.7e-39 130.0 73.8 0.00026 20.7 0.0 24.0 26 1 0 26 26 25 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFP11785.1 - 5e-33 111.0 45.4 0.00035 21.2 0.4 21.1 15 6 7 22 22 20 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP11785.1 - 2.3e-32 108.5 91.1 0.00071 19.5 0.2 26.2 28 2 2 30 30 26 8 Tetratricopeptide repeat TPR_16 PF13432.6 KFP11785.1 - 4e-27 94.6 34.0 1e-07 32.5 0.2 13.7 12 5 6 18 18 16 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFP11785.1 - 1.3e-25 89.5 57.5 0.0002 21.6 0.2 16.1 14 4 3 17 17 14 8 Tetratricopeptide repeat TPR_17 PF13431.6 KFP11785.1 - 1.6e-24 84.5 46.8 0.0011 19.2 0.2 20.1 21 0 0 21 21 19 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP11785.1 - 2.5e-23 81.5 58.0 0.0011 18.7 0.0 18.2 19 3 3 22 22 20 7 TPR repeat TPR_8 PF13181.6 KFP11785.1 - 1.3e-20 71.8 79.9 0.0028 17.7 0.3 21.8 26 0 0 26 26 21 6 Tetratricopeptide repeat TPR_9 PF13371.6 KFP11785.1 - 9.3e-14 51.3 9.5 0.0007 19.7 0.1 8.9 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP11785.1 - 5.5e-09 35.4 43.6 0.58 10.3 0.1 15.6 20 1 0 20 20 14 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFP11785.1 - 2.8e-08 33.3 50.6 3.4e-07 29.8 1.7 9.0 8 3 2 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP11785.1 - 1.3e-07 31.7 48.9 0.0045 17.2 0.4 11.1 7 4 4 11 11 11 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP11785.1 - 2.2e-07 31.1 44.7 1.4 9.7 0.0 15.6 18 0 0 18 18 14 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KFP11785.1 - 0.00083 18.5 7.1 0.063 12.3 0.0 4.2 4 2 1 5 5 5 2 Coatomer WD associated region BTAD PF03704.17 KFP11785.1 - 0.0057 17.1 0.1 0.0057 17.1 0.1 5.5 5 1 2 7 7 6 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 KFP11785.1 - 0.011 16.3 0.7 27 5.8 0.0 5.5 6 0 0 6 6 3 0 Tetratricopeptide repeat TolB_N PF04052.13 KFP11785.1 - 0.014 15.5 0.1 0.065 13.4 0.1 2.1 2 0 0 2 2 2 0 TolB amino-terminal domain RPN7 PF10602.9 KFP11785.1 - 0.025 14.3 14.6 1.4 8.6 3.1 7.5 5 2 0 6 6 5 0 26S proteasome subunit RPN7 ChAPs PF09295.10 KFP11785.1 - 0.043 12.8 8.7 23 3.8 0.2 6.1 6 0 0 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) Imm71 PF15602.6 KFP11785.1 - 0.056 13.5 1.9 0.51 10.4 0.1 3.1 2 0 0 2 2 2 0 Immunity protein 71 FlbT PF07378.11 KFP11785.1 - 0.25 11.4 2.4 3.1 7.9 0.4 3.6 2 0 0 2 2 2 0 Flagellar protein FlbT TPR_10 PF13374.6 KFP11785.1 - 0.66 9.9 28.1 23 5.0 0.0 11.6 13 0 0 13 13 10 0 Tetratricopeptide repeat Lipoprotein_3 PF00938.17 KFP11785.1 - 0.67 10.2 2.8 1.4 9.2 0.3 2.8 2 0 0 2 2 2 0 Lipoprotein TPR_20 PF14561.6 KFP11785.1 - 0.76 10.1 0.0 0.76 10.1 0.0 7.7 9 1 1 10 10 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP11785.1 - 0.88 9.7 14.7 0.1 12.7 0.5 5.5 6 0 0 6 6 3 0 Fis1 C-terminal tetratricopeptide repeat Retrotran_gag_2 PF14223.6 KFP11785.1 - 1.3 8.7 11.1 0.23 11.1 0.1 4.1 3 1 0 4 4 4 0 gag-polypeptide of LTR copia-type HemY_N PF07219.13 KFP11785.1 - 8.7 6.6 12.6 77 3.5 0.0 6.7 6 1 1 7 7 7 0 HemY protein N-terminus DUF3856 PF12968.7 KFP11785.1 - 10 6.2 11.1 56 3.8 0.1 5.8 4 4 1 5 5 5 0 Domain of Unknown Function (DUF3856) Sulfatase PF00884.23 KFP11786.1 - 7.7e-42 143.7 0.0 1.6e-41 142.7 0.0 1.5 1 1 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 KFP11786.1 - 5.7e-06 26.2 0.2 0.00023 21.0 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function DUF229 PF02995.17 KFP11786.1 - 1.5e-05 23.8 0.1 0.00017 20.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KFP11786.1 - 2.3e-05 24.6 0.0 6.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 KFP11786.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KFP11786.1 - 0.0024 17.6 0.1 0.0094 15.6 0.0 2.0 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KFP11786.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) COX_ARM PF06481.14 KFP11786.1 - 0.086 12.8 0.5 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 COX Aromatic Rich Motif Rieske_2 PF13806.6 KFP11787.1 - 2.7e-06 27.2 0.0 6.6e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KFP11787.1 - 4.7e-05 23.2 0.1 0.00027 20.8 0.1 2.0 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rogdi_lz PF10259.9 KFP11789.1 - 9e-52 176.2 0.4 1.1e-51 175.9 0.4 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NAD_binding_2 PF03446.15 KFP11790.1 - 6.6e-39 133.6 0.0 1.4e-38 132.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFP11790.1 - 7e-23 81.2 1.1 1.3e-22 80.3 1.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 KFP11790.1 - 3.5e-14 53.0 0.6 1.1e-13 51.3 0.6 1.9 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.17 KFP11790.1 - 9.6e-08 32.5 0.0 2.6e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFP11790.1 - 9.4e-05 21.8 0.0 0.00086 18.7 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFP11790.1 - 0.00026 21.1 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KFP11790.1 - 0.00039 20.1 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFP11790.1 - 0.0077 16.1 0.0 0.0077 16.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFP11790.1 - 0.032 14.5 0.0 0.072 13.4 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KFP11790.1 - 0.16 11.9 0.3 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AT_hook PF02178.19 KFP11790.1 - 4.3 7.5 11.9 0.1 12.5 4.1 2.6 2 0 0 2 2 2 0 AT hook motif JUPITER PF17054.5 KFP11791.1 - 9e-08 32.0 7.0 3e-05 23.7 0.1 3.6 2 1 2 4 4 4 3 Microtubule-Associated protein Jupiter MBDa PF16564.5 KFP11791.1 - 0.0043 17.2 0.1 0.076 13.2 0.0 2.2 2 0 0 2 2 2 1 p55-binding region of Methyl-CpG-binding domain proteins MBD Myb_DNA-bind_7 PF15963.5 KFP11792.1 - 0.005 16.7 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KFP11792.1 - 0.021 15.0 0.1 0.087 13.0 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain ANAPC4_WD40 PF12894.7 KFP11793.1 - 1.2e-12 47.9 2.5 1.1e-05 25.7 0.1 5.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFP11793.1 - 1.4e-06 27.7 26.0 0.022 13.8 5.5 5.5 2 1 3 6 6 6 3 Coatomer WD associated region TPR_7 PF13176.6 KFP11793.1 - 0.00017 21.4 20.9 0.34 11.0 0.1 9.7 9 2 2 11 11 11 1 Tetratricopeptide repeat Clathrin PF00637.20 KFP11793.1 - 0.00027 20.8 28.0 0.72 9.7 5.6 7.0 3 1 5 8 8 8 3 Region in Clathrin and VPS WD40 PF00400.32 KFP11793.1 - 0.026 15.4 12.0 7.4 7.6 0.3 5.6 6 0 0 6 6 5 0 WD domain, G-beta repeat RNase_HII PF01351.18 KFP11793.1 - 0.029 14.2 0.4 0.067 13.0 0.4 1.6 1 0 0 1 1 1 0 Ribonuclease HII DUF2524 PF10732.9 KFP11793.1 - 0.13 12.5 1.6 1.3 9.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) TPR_2 PF07719.17 KFP11793.1 - 0.35 11.1 40.5 0.74 10.1 0.1 10.7 11 2 2 13 13 13 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 KFP11793.1 - 1.7 8.9 8.2 2.4 8.4 1.6 4.0 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 TPR_12 PF13424.6 KFP11793.1 - 7 7.0 33.9 0.34 11.2 1.7 7.9 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP11793.1 - 7.3 7.2 25.2 9.2 6.9 1.8 7.7 6 4 2 9 9 9 0 Tetratricopeptide repeat L_HMGIC_fpl PF10242.9 KFP11794.1 - 3.7e-05 24.0 1.4 3.7e-05 24.0 1.4 2.3 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 KFP11794.1 - 0.0004 19.9 0.1 0.0004 19.9 0.1 2.1 2 1 1 3 3 3 1 Clc-like Claudin_3 PF06653.11 KFP11794.1 - 0.00076 19.5 4.5 0.21 11.5 0.1 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Claudin_2 PF13903.6 KFP11794.1 - 0.0012 18.7 8.5 0.02 14.6 8.5 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4418 PF14387.6 KFP11794.1 - 0.0065 16.7 1.4 0.0065 16.7 1.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4418) SUR7 PF06687.12 KFP11794.1 - 0.1 12.2 3.0 0.3 10.7 3.0 1.9 1 1 0 1 1 1 0 SUR7/PalI family PulG PF11773.8 KFP11794.1 - 0.1 12.4 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Virul_fac_BrkB PF03631.15 KFP11794.1 - 0.1 12.2 7.5 0.04 13.5 4.2 1.8 2 0 0 2 2 2 0 Virulence factor BrkB Neurensin PF14927.6 KFP11794.1 - 1.6 8.4 4.9 0.9 9.2 0.5 2.5 1 1 1 2 2 2 0 Neurensin Telomere_reg-2 PF10193.9 KFP11795.1 - 2.6e-35 121.2 0.7 9.3e-35 119.4 0.2 2.2 2 0 0 2 2 2 1 Telomere length regulation protein RIX1 PF08167.12 KFP11795.1 - 9.1e-05 22.3 0.1 0.48 10.1 0.0 3.3 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis RRM_1 PF00076.22 KFP11796.1 - 2.7e-20 72.0 0.0 4.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP11796.1 - 0.00038 20.5 0.0 0.00097 19.2 0.0 1.7 1 0 0 1 1 1 1 Limkain b1 SPX PF03105.19 KFP11796.1 - 0.00078 19.5 29.6 0.00092 19.2 29.6 1.1 1 0 0 1 1 1 1 SPX domain RRM_3 PF08777.11 KFP11796.1 - 0.0012 18.8 0.0 0.0038 17.3 0.0 1.8 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFP11796.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFP11796.1 - 0.0034 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 KFP11796.1 - 0.0039 15.8 26.3 0.0047 15.5 26.3 1.1 1 0 0 1 1 1 1 Macoilin family RRM_7 PF16367.5 KFP11796.1 - 0.0039 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFP11796.1 - 0.0049 16.7 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif LAP1C PF05609.12 KFP11796.1 - 0.064 12.3 18.5 0.085 11.9 18.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 KFP11796.1 - 2.3 7.5 36.5 3.1 7.0 36.5 1.1 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 KFP11796.1 - 3 5.5 20.4 3.7 5.2 20.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_S64 PF08192.11 KFP11796.1 - 3.3 6.1 22.4 3.8 5.9 22.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 LTD PF00932.19 KFP11797.1 - 2.5e-11 43.9 0.0 1.5e-07 31.8 0.0 2.8 2 1 0 2 2 2 2 Lamin Tail Domain PX PF00787.24 KFP11798.1 - 0.028 14.4 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 PX domain SelP_N PF04592.14 KFP11798.1 - 0.34 10.3 7.8 0.39 10.1 7.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4615 PF15393.6 KFP11799.1 - 2.3e-44 151.4 2.8 2.3e-44 151.4 2.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) NopRA1 PF16201.5 KFP11799.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Zip PF02535.22 KFP11799.1 - 0.72 9.0 2.0 0.76 8.9 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PDE4_UCR PF18100.1 KFP11799.1 - 0.97 10.1 6.4 1.3 9.7 4.6 2.2 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Amidohydro_1 PF01979.20 KFP11800.1 - 5.1e-18 65.5 0.1 7.7e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP11800.1 - 3.2e-06 26.9 0.3 9.5e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family ATP-synt_C PF00137.21 KFP11801.1 - 2.9e-35 120.4 32.3 1.2e-22 80.0 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TLD PF07534.16 KFP11802.1 - 6.6e-28 97.7 0.0 1.2e-13 51.4 0.0 2.3 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.18 KFP11802.1 - 1.8e-25 89.9 0.0 2.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Laminin_N PF00055.17 KFP11803.1 - 2.9e-62 210.3 4.2 1.7e-61 207.8 0.0 3.1 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) NTR PF01759.21 KFP11803.1 - 2.4e-29 101.3 1.6 4.4e-29 100.4 1.6 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.24 KFP11803.1 - 1e-07 32.0 5.8 1e-07 32.0 5.8 4.3 4 1 1 5 5 5 1 Laminin EGF domain Cadherin PF00028.17 KFP11805.1 - 1.9e-82 271.9 1.9 4.3e-16 59.1 0.0 6.5 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFP11805.1 - 9.7e-14 51.0 1.7 1.4e-12 47.3 0.1 3.5 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 KFP11805.1 - 2.8e-06 27.3 7.1 0.29 11.1 0.2 5.2 4 1 1 5 5 5 2 Cadherin-like Cadherin_C_2 PF16492.5 KFP11805.1 - 0.00083 20.1 2.7 0.0035 18.0 0.8 3.0 2 1 0 2 2 2 1 Cadherin cytoplasmic C-terminal VEGF_C PF14554.6 KFP11805.1 - 0.073 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 VEGF heparin-binding domain Syndecan PF01034.20 KFP11805.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain SCP2 PF02036.17 KFP11806.1 - 1.5e-23 83.2 0.1 1.8e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFP11806.1 - 0.05 13.9 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFP11806.1 - 0.097 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain DUF3504 PF12012.8 KFP11807.1 - 1.3e-14 54.5 0.4 4.3e-14 52.8 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) Phage_int_SAM_5 PF13102.6 KFP11807.1 - 0.0021 18.4 0.3 0.0058 17.0 0.3 1.7 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 KFP11807.1 - 0.096 13.2 0.2 0.35 11.4 0.1 2.0 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KFP11807.1 - 0.12 12.7 0.5 19 5.6 0.1 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain SOSSC PF15925.5 KFP11808.1 - 5e-23 82.3 0.8 3.5e-22 79.6 0.8 1.9 1 1 0 1 1 1 1 SOSS complex subunit C PX PF00787.24 KFP11809.1 - 7.8e-24 83.8 1.8 1.6e-23 82.8 1.8 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFP11809.1 - 1.5e-09 37.7 1.9 8.9e-05 22.1 0.0 2.5 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.18 KFP11809.1 - 1.7e-07 31.1 0.3 1.7e-07 31.1 0.3 1.6 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.9 KFP11809.1 - 0.0034 16.9 0.1 0.0066 15.9 0.1 1.4 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein MFS_1 PF07690.16 KFP11810.1 - 9.5e-09 34.6 35.2 9.5e-09 34.6 35.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily AKAP2_C PF15304.6 KFP11811.1 - 5.6e-14 52.2 14.3 5.6e-14 52.2 14.3 3.2 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Misat_Tub_SegII PF10644.9 KFP11811.1 - 0.045 14.1 0.4 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain Paralemmin PF03285.15 KFP11812.1 - 1.4e-92 310.7 20.2 3.7e-92 309.3 20.2 1.6 1 1 0 1 1 1 1 Paralemmin Sulfotransfer_1 PF00685.27 KFP11813.1 - 1.1e-32 113.6 0.0 1.3e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11813.1 - 8.8e-11 42.6 0.0 1.3e-10 42.1 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP11813.1 - 0.0051 16.8 0.0 0.084 12.8 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family UDPGT PF00201.18 KFP11814.1 - 6.6e-81 272.6 0.3 7.2e-81 272.5 0.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP11814.1 - 3.4e-07 30.4 0.0 5.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 KFP11814.1 - 0.027 14.9 0.0 0.041 14.3 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Clusterin PF01093.17 KFP11815.1 - 6.4e-89 299.0 8.4 1.7e-85 287.6 8.4 2.0 1 1 0 1 1 1 1 Clusterin DUF4398 PF14346.6 KFP11815.1 - 0.1 13.2 5.2 0.15 12.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF1664 PF07889.12 KFP11816.1 - 0.0012 18.8 13.0 1.7 8.7 0.1 5.0 1 1 5 6 6 6 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFP11816.1 - 0.0041 17.6 8.6 0.76 10.3 0.9 5.1 2 1 2 4 4 4 1 Nucleopolyhedrovirus P10 protein WEMBL PF05701.11 KFP11816.1 - 0.0088 14.8 1.6 0.018 13.7 1.6 1.5 1 0 0 1 1 1 1 Weak chloroplast movement under blue light T3SSipB PF16535.5 KFP11816.1 - 0.021 15.3 0.9 0.2 12.1 0.1 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB ABC_tran_CTD PF16326.5 KFP11816.1 - 0.042 14.1 7.0 0.64 10.3 0.2 3.9 4 0 0 4 4 4 0 ABC transporter C-terminal domain BORCS7 PF16088.5 KFP11816.1 - 0.043 14.1 5.5 0.21 11.8 1.2 3.2 3 0 0 3 3 2 0 BLOC-1-related complex sub-unit 7 CotJB PF12652.7 KFP11816.1 - 0.047 13.9 0.3 0.34 11.2 0.2 2.5 2 0 0 2 2 2 0 CotJB protein MCPsignal PF00015.21 KFP11816.1 - 0.05 13.4 5.9 0.53 10.1 0.2 2.9 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ADIP PF11559.8 KFP11816.1 - 0.064 13.3 0.3 0.064 13.3 0.3 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.9 KFP11816.1 - 0.07 13.9 3.6 2.3 9.0 0.2 3.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fez1 PF06818.15 KFP11816.1 - 0.079 13.4 7.4 12 6.3 4.7 3.1 1 1 2 3 3 3 0 Fez1 DUF948 PF06103.11 KFP11816.1 - 0.22 11.8 12.9 17 5.8 0.2 5.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) LRRFIP PF09738.9 KFP11816.1 - 0.39 10.2 6.0 0.14 11.6 3.2 1.6 1 1 0 1 1 1 0 LRRFIP family Lebercilin PF15619.6 KFP11816.1 - 0.87 9.2 9.7 33 4.1 6.3 3.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SPATA1_C PF15743.5 KFP11816.1 - 1 9.4 4.8 1.3 9.1 0.4 2.9 3 1 0 3 3 2 0 Spermatogenesis-associated C-terminus FlaC_arch PF05377.11 KFP11816.1 - 1.4 9.3 10.3 18 5.8 0.0 5.6 7 0 0 7 7 5 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 KFP11816.1 - 1.5 9.2 6.1 20 5.6 0.4 3.8 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 Myosin_tail_1 PF01576.19 KFP11816.1 - 1.5 6.5 8.0 0.16 9.7 0.8 2.3 2 1 0 3 3 3 0 Myosin tail UPF0184 PF03670.13 KFP11816.1 - 1.9 8.9 5.1 6.2 7.3 0.2 3.7 3 1 2 5 5 5 0 Uncharacterised protein family (UPF0184) DUF2703 PF10865.8 KFP11816.1 - 2.2 8.5 5.9 0.33 11.1 0.4 2.5 3 0 0 3 3 1 0 Domain of unknown function (DUF2703) TolA_bind_tri PF16331.5 KFP11816.1 - 3.9 7.6 16.6 0.95 9.6 1.9 3.9 2 1 2 4 4 4 0 TolA binding protein trimerisation ATG16 PF08614.11 KFP11816.1 - 4.7 7.4 9.5 2.6 8.2 3.6 3.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Exostosin PF03016.15 KFP11817.1 - 0.00031 20.0 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Exostosin family PBSX_XtrA PF17356.2 KFP11817.1 - 0.014 15.3 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Flg_bbr_C PF06429.13 KFP11817.1 - 0.028 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal PP2C PF00481.21 KFP11820.1 - 3.7e-27 95.6 0.0 4.5e-12 46.1 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 KFP11820.1 - 0.00014 21.9 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFP11820.1 - 0.019 14.6 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 0 Protein phosphatase 2C Mon2_C PF16206.5 KFP11822.1 - 0 1340.0 5.6 0 1338.8 4.0 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DCB PF16213.5 KFP11822.1 - 3e-57 193.1 5.9 3e-57 193.1 5.9 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFP11822.1 - 7.3e-55 185.2 2.4 7.3e-55 185.2 2.4 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFP11822.1 - 6.3e-18 64.4 0.4 1.4e-15 56.9 0.0 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KFP11822.1 - 4.6e-05 23.3 1.3 14 6.3 0.0 5.5 4 0 0 4 4 4 1 HEAT repeat Keratin_assoc PF09775.9 KFP11822.1 - 0.016 14.9 0.1 0.66 9.6 0.1 2.7 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 SelK_SelG PF10961.8 KFP11822.1 - 0.87 10.2 3.4 0.6 10.8 0.9 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG UCH PF00443.29 KFP11824.1 - 8.3e-85 284.4 0.1 1.2e-84 283.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 KFP11824.1 - 2.6e-40 136.3 0.1 5.3e-40 135.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUSP PF06337.12 KFP11824.1 - 1.1e-19 70.9 0.9 1.1e-19 70.9 0.9 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KFP11824.1 - 2.4e-15 56.9 0.0 2.5e-08 33.9 0.0 3.5 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KFP11824.1 - 7.2e-09 35.7 0.5 2.8e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 KFP11824.1 - 0.00037 19.9 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 CW_binding_1 PF01473.20 KFP11824.1 - 0.058 13.7 4.7 0.32 11.4 4.7 2.3 1 0 0 1 1 1 0 Putative cell wall binding repeat TAFA PF12020.8 KFP11826.1 - 1.1e-32 112.3 9.0 1.5e-32 111.9 9.0 1.1 1 0 0 1 1 1 1 TAFA family Ras PF00071.22 KFP11828.1 - 2.6e-44 150.7 0.2 2.7e-44 150.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11828.1 - 2.9e-21 75.9 0.0 4.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11828.1 - 1.1e-09 38.0 0.0 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP11828.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP11828.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MCR_beta PF02241.18 KFP11828.1 - 0.063 12.9 0.1 0.068 12.8 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Sulfatase PF00884.23 KFP11829.1 - 2.5e-45 155.2 0.1 3.7e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP11829.1 - 3.3e-05 24.6 0.0 8.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Ets PF00178.22 KFP11830.1 - 2.1e-33 114.6 2.5 3.1e-33 114.1 2.5 1.2 1 0 0 1 1 1 1 Ets-domain Bromodomain PF00439.25 KFP11831.1 - 6.3e-33 112.7 1.0 3.1e-18 65.6 0.0 3.6 3 0 0 3 3 3 2 Bromodomain WD40 PF00400.32 KFP11831.1 - 3.6e-30 103.5 17.0 5.8e-06 26.9 0.2 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11831.1 - 7.8e-06 26.1 0.2 0.25 11.7 0.1 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP11831.1 - 0.0027 16.7 0.8 0.92 8.4 0.0 4.3 3 2 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Auxin_resp PF06507.13 KFP11831.1 - 0.05 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Auxin response factor NTP_transf_7 PF07984.12 KFP11832.1 - 1.2e-158 527.4 3.4 1.4e-158 527.2 3.4 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Snf7 PF03357.21 KFP11833.1 - 3.7e-16 59.2 17.7 4.4e-16 59.0 17.7 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 KFP11833.1 - 3.2e-05 23.9 7.6 4.4e-05 23.5 7.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway FlxA PF14282.6 KFP11833.1 - 0.037 14.0 7.4 0.04 13.9 0.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Mu-like_Pro PF10123.9 KFP11833.1 - 0.047 13.2 9.1 0.059 12.9 9.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DMSP_lyase PF16867.5 KFP11833.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF948 PF06103.11 KFP11833.1 - 0.16 12.3 8.8 0.054 13.7 4.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.12 KFP11833.1 - 0.23 11.3 10.1 0.4 10.5 0.6 2.6 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GrpE PF01025.19 KFP11833.1 - 0.64 9.7 10.6 1.1 8.9 10.5 1.4 1 1 0 1 1 1 0 GrpE T-box PF00907.22 KFP11834.1 - 1.4e-41 142.8 0.6 2.8e-23 83.2 0.0 2.3 1 1 0 2 2 2 2 T-box BRICHOS PF04089.14 KFP11835.1 - 2.6e-18 66.0 0.0 7.4e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 BRICHOS domain 7tm_1 PF00001.21 KFP11836.1 - 2.4e-40 138.5 22.7 3.2e-40 138.1 22.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP11836.1 - 0.00027 20.3 20.2 0.00048 19.5 3.3 2.5 1 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF3318 PF11780.8 KFP11836.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) 7tm_1 PF00001.21 KFP11837.1 - 1.9e-36 125.7 19.7 2.6e-36 125.3 19.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP11837.1 - 5e-05 22.7 14.6 5.5e-05 22.6 1.1 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KFP11838.1 - 1.5e-52 178.5 25.2 1.7e-52 178.4 24.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP11838.1 - 3.9e-08 33.0 26.5 5.4e-08 32.5 26.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.15 KFP11838.1 - 0.12 12.3 17.4 0.034 14.1 2.7 2.7 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 KFP11838.1 - 0.49 10.0 34.3 1.5 8.4 32.4 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KFP11839.1 - 4.4e-06 26.2 12.2 5.8e-06 25.8 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP11839.1 - 0.1 12.2 10.9 0.21 11.2 10.9 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx TFIID-31kDa PF02291.15 KFP11840.1 - 4.2e-32 110.8 0.0 6.7e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFP11840.1 - 0.018 15.4 0.1 0.04 14.3 0.1 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFP11840.1 - 0.02 15.2 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein CENP-T_C PF15511.6 KFP11840.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Kinesin PF00225.23 KFP11841.1 - 4.7e-102 341.3 0.3 4.7e-102 341.3 0.3 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP11841.1 - 3.1e-15 56.4 0.0 3.1e-15 56.4 0.0 3.6 4 0 0 4 4 4 1 Microtubule binding TCR PF03638.15 KFP11841.1 - 4.4 7.7 19.3 8.7 6.7 19.3 1.5 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain PDZ PF00595.24 KFP11842.1 - 2.3e-17 63.1 0.2 2.7e-17 62.9 0.2 1.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP11842.1 - 2.7e-10 39.9 0.1 4.5e-10 39.2 0.0 1.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP11842.1 - 3.2e-08 33.8 0.0 3.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 KFP11843.1 - 3.3e-54 182.9 0.3 4e-54 182.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP11843.1 - 8.4e-32 109.9 0.2 1.5e-31 109.1 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP11843.1 - 9.2e-12 44.8 0.3 1e-11 44.6 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP11843.1 - 1.7e-05 24.4 0.1 3.6e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP11843.1 - 0.0016 17.9 0.1 0.0024 17.3 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP11843.1 - 0.0092 16.1 0.1 0.018 15.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP11843.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B Arrestin_N PF00339.29 KFP11844.1 - 9.5e-41 139.3 0.0 5.4e-37 127.1 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFP11844.1 - 2.9e-25 89.3 0.8 4.6e-25 88.6 0.8 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain BatD PF13584.6 KFP11844.1 - 0.032 13.0 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance CBM49 PF09478.10 KFP11844.1 - 0.22 11.8 1.0 0.39 11.0 1.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Pec_lyase_N PF04431.13 KFP11844.1 - 0.43 10.9 1.5 0.93 9.8 1.5 1.6 1 1 0 1 1 1 0 Pectate lyase, N terminus TAP42 PF04177.12 KFP11846.1 - 8.2e-75 251.9 0.2 9.3e-75 251.7 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family PBSX_XtrA PF17356.2 KFP11846.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Phage_prot_Gp6 PF05133.14 KFP11846.1 - 0.13 11.4 1.7 0.19 10.8 1.7 1.3 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Ribosomal_60s PF00428.19 KFP11846.1 - 0.64 10.6 4.6 1.8 9.2 0.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein TFIIS_M PF07500.14 KFP11846.1 - 2.7 8.5 6.3 0.26 11.8 1.6 1.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain wnt PF00110.19 KFP11847.1 - 4.8e-113 377.8 10.1 5.5e-113 377.6 10.1 1.0 1 0 0 1 1 1 1 wnt family LRR_8 PF13855.6 KFP11848.1 - 4.2e-61 202.6 45.1 1.2e-11 44.2 2.9 10.5 6 2 5 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 KFP11848.1 - 2.8e-45 151.5 42.5 1.6e-06 28.3 0.0 10.4 9 1 0 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP11848.1 - 8.1e-16 56.1 56.1 0.71 10.7 0.2 17.9 17 3 0 17 17 17 6 Leucine Rich Repeat LRR_9 PF14580.6 KFP11848.1 - 8e-10 38.5 8.3 0.018 14.6 0.1 6.3 4 2 2 7 7 7 3 Leucine-rich repeat LRR_6 PF13516.6 KFP11848.1 - 8.5e-09 34.8 56.0 4.8 7.5 0.1 16.8 18 0 0 18 18 18 5 Leucine Rich repeat LRR_5 PF13306.6 KFP11848.1 - 5e-05 23.3 0.0 0.094 12.7 0.0 3.0 4 0 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFP11848.1 - 0.037 13.7 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain TNF PF00229.18 KFP11849.1 - 3.7e-09 36.6 0.4 1.7e-08 34.4 0.4 1.9 1 1 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.18 KFP11849.1 - 1.4e-07 31.1 45.9 0.00012 21.8 45.9 2.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) OCRL_clath_bd PF16726.5 KFP11850.1 - 2.1e-32 111.4 0.3 5e-32 110.2 0.3 1.7 1 0 0 1 1 1 1 Inositol polyphosphate 5-phosphatase clathrin binding domain RhoGAP PF00620.27 KFP11850.1 - 5.3e-24 84.8 0.2 1e-23 83.9 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFP11850.1 - 1.1e-13 51.2 0.0 1.8e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AbbA_antirepres PF14156.6 KFP11850.1 - 0.095 12.6 0.2 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Antirepressor AbbA SNF2_N PF00176.23 KFP11851.1 - 4.5e-50 170.3 0.1 5.1e-48 163.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP11851.1 - 2.5e-20 72.9 0.1 3.6e-19 69.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP11851.1 - 7.1e-13 48.9 0.0 2.9e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KFP11851.1 - 5.1e-05 22.3 0.0 7.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SWI2_SNF2 PF18766.1 KFP11851.1 - 0.0002 21.1 0.0 0.00079 19.2 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KFP11851.1 - 0.00021 20.6 0.0 0.00036 19.8 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KFP11851.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KFP11851.1 - 0.017 14.7 0.1 0.071 12.7 0.0 2.0 2 0 0 2 2 2 0 DEAD_2 DUF2785 PF10978.8 KFP11851.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) TK PF00265.18 KFP11851.1 - 0.21 11.5 0.2 32 4.3 0.0 2.6 3 0 0 3 3 3 0 Thymidine kinase UCH PF00443.29 KFP11852.1 - 3e-26 92.5 1.0 3.5e-26 92.2 1.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP11852.1 - 0.0004 20.1 0.1 0.00055 19.6 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Gag_p30 PF02093.16 KFP11853.1 - 2.8e-28 98.9 0.0 3.5e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein DUF1743 PF08489.11 KFP11853.1 - 0.0054 16.8 0.0 0.12 12.5 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF1743) Gag_p24 PF00607.20 KFP11853.1 - 0.038 13.8 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) zf-C3Hc3H PF13891.6 KFP11854.1 - 2.1e-15 56.8 7.5 3.2e-15 56.2 7.5 1.3 1 0 0 1 1 1 1 Potential DNA-binding domain zf-C3Hc3H PF13891.6 KFP11855.1 - 4e-17 62.3 5.1 7.7e-17 61.4 5.1 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 KFP11855.1 - 0.033 14.0 11.8 0.43 10.4 0.1 3.6 3 1 0 3 3 3 0 CCCH zinc finger in TRM13 protein WRC PF08879.10 KFP11855.1 - 0.1 12.3 0.8 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 WRC CxC6 PF18721.1 KFP11855.1 - 4.4 7.7 6.8 9.2 6.6 2.9 2.3 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Cyclin_N PF00134.23 KFP11856.1 - 3.9e-16 59.0 1.0 8.4e-13 48.2 0.2 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain UPF0253 PF06786.12 KFP11856.1 - 0.11 12.7 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) DUF3510 PF12022.8 KFP11856.1 - 0.13 12.6 0.7 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Metallophos PF00149.28 KFP11857.1 - 2.1e-15 57.8 0.0 2.6e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_C14 PF00656.22 KFP11858.1 - 2.2e-27 96.6 0.0 2.5e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Hormone_recep PF00104.30 KFP11859.1 - 6.3e-46 156.6 0.8 1.1e-45 155.7 0.8 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP11859.1 - 5.5e-32 110.0 16.3 1.1e-31 109.1 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FAA_hydro_N_2 PF18288.1 KFP11859.1 - 0.044 14.2 0.9 0.55 10.7 0.1 3.1 2 2 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DASH_Spc19 PF08287.11 KFP11860.1 - 0.026 14.4 1.0 0.035 14.0 1.0 1.1 1 0 0 1 1 1 0 Spc19 NPF PF16601.5 KFP11861.1 - 1.1e-54 185.8 18.1 2.3e-54 184.7 18.1 1.6 1 0 0 1 1 1 1 Rabosyn-5 repeating NPF sequence-motif Rbsn PF11464.8 KFP11861.1 - 1.8e-27 94.8 16.5 1.8e-15 56.4 4.0 3.1 3 0 0 3 3 3 2 Rabenosyn Rab binding domain FYVE PF01363.21 KFP11861.1 - 5.1e-18 65.0 6.1 1.6e-17 63.4 6.1 1.9 1 0 0 1 1 1 1 FYVE zinc finger TerY_C PF15616.6 KFP11861.1 - 0.029 14.5 0.1 0.12 12.5 0.1 2.1 1 0 0 1 1 1 0 TerY-C metal binding domain RNA_POL_M_15KD PF02150.16 KFP11861.1 - 0.036 13.9 5.9 0.037 13.9 1.2 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-Di19 PF05605.12 KFP11861.1 - 0.072 13.4 0.1 0.072 13.4 0.1 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_12 PF11331.8 KFP11861.1 - 0.51 10.2 3.2 0.32 10.8 0.2 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_9 PF14369.6 KFP11861.1 - 0.55 10.5 6.6 0.25 11.6 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon IBR PF01485.21 KFP11861.1 - 0.91 9.8 8.4 0.17 12.1 2.9 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-AD PF07776.15 KFP11861.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.1 3 1 2 5 5 4 0 Zinc-finger associated domain (zf-AD) C1_1 PF00130.22 KFP11861.1 - 3.4 7.6 9.7 0.88 9.5 3.6 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 KFP11861.1 - 3.8 7.6 10.1 0.55 10.3 0.4 3.2 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KFP11861.1 - 6.8 6.8 11.7 0.47 10.5 2.7 3.0 3 0 0 3 3 3 0 Double zinc ribbon TRH PF05438.12 KFP11862.1 - 8.2e-96 320.0 9.7 6.7e-93 310.5 5.4 2.0 2 0 0 2 2 2 2 Thyrotropin-releasing hormone (TRH) Chal_sti_synt_C PF02797.15 KFP11862.1 - 0.046 13.7 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Prothymosin PF03247.14 KFP11862.1 - 3.1 8.3 10.6 0.62 10.5 3.7 2.6 2 1 0 2 2 2 0 Prothymosin/parathymosin family Tmemb_cc2 PF10267.9 KFP11863.1 - 3.7e-170 566.4 15.0 3.7e-170 566.4 15.0 1.8 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein LMBR1 PF04791.16 KFP11863.1 - 0.0012 17.8 0.8 0.0012 17.8 0.8 2.2 2 0 0 2 2 2 1 LMBR1-like membrane protein CbiA PF01656.23 KFP11863.1 - 0.017 15.2 0.3 0.086 12.9 0.0 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0565 PF10561.9 KFP11863.1 - 0.072 12.3 5.0 0.053 12.7 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Exonuc_VII_L PF02601.15 KFP11863.1 - 0.82 9.2 24.1 1.1 8.8 9.4 3.1 3 0 0 3 3 3 0 Exonuclease VII, large subunit 7tm_1 PF00001.21 KFP11864.1 - 2.8e-45 154.7 15.0 3.5e-45 154.4 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.9 KFP11864.1 - 2e-26 91.5 1.7 2e-26 91.5 1.7 2.1 2 0 0 2 2 2 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srv PF10323.9 KFP11864.1 - 4.8e-09 36.0 18.3 6.4e-09 35.6 18.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFP11864.1 - 4e-08 32.9 15.3 1.3e-07 31.2 15.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFP11864.1 - 5.3e-08 32.6 16.3 6.8e-08 32.2 16.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11864.1 - 0.019 14.7 16.6 0.15 11.8 16.6 1.9 1 1 0 1 1 1 0 Olfactory receptor WD40 PF00400.32 KFP11865.1 - 2.1e-15 56.8 15.7 2.9e-06 27.9 0.0 7.5 7 1 0 7 7 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11865.1 - 1.2e-11 44.7 0.8 0.015 15.6 0.1 5.1 5 1 0 5 5 4 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFP11865.1 - 3.7e-05 23.0 8.8 0.005 15.9 0.3 5.0 5 1 0 5 5 5 2 Coatomer WD associated region eIF2A PF08662.11 KFP11865.1 - 0.0015 18.4 0.8 0.32 10.9 0.0 3.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.6 KFP11865.1 - 0.011 15.7 9.2 0.054 13.5 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP11865.1 - 0.014 15.6 10.1 0.19 12.0 0.3 3.9 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Prok-RING_4 PF14447.6 KFP11865.1 - 0.016 15.0 2.2 0.068 13.0 2.2 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ge1_WD40 PF16529.5 KFP11865.1 - 0.019 13.9 0.9 0.25 10.3 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Clathrin PF00637.20 KFP11865.1 - 0.026 14.4 3.6 0.27 11.1 0.1 3.5 1 1 3 4 4 4 0 Region in Clathrin and VPS TPR_2 PF07719.17 KFP11865.1 - 0.15 12.3 20.8 0.18 12.0 0.8 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP11865.1 - 0.69 10.2 9.5 1 9.7 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP11865.1 - 4.3 8.4 9.3 41 5.4 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KFP11865.1 - 7.3 6.5 10.0 11 5.9 2.5 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HhH-GPD PF00730.25 KFP11866.1 - 5.5e-05 23.6 0.0 6.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L32e PF01655.18 KFP11867.1 - 5.1e-58 194.2 3.4 6e-58 193.9 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 WD40 PF00400.32 KFP11868.1 - 4.2e-23 81.2 21.2 0.00053 20.7 0.2 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11868.1 - 1.4e-07 31.7 4.9 0.014 15.7 0.1 4.7 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP11868.1 - 0.018 14.1 1.4 0.91 8.4 0.0 2.8 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VHL PF01847.16 KFP11869.1 - 1.3e-37 127.6 0.1 2.1e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 VHL beta domain VHL_C PF17211.3 KFP11869.1 - 5e-30 103.3 2.8 7.6e-30 102.7 2.8 1.3 1 0 0 1 1 1 1 VHL box domain STAT2_C PF12188.8 KFP11869.1 - 0.23 11.4 0.6 0.82 9.6 0.3 2.0 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal UPF0020 PF01170.18 KFP11870.1 - 1.8e-48 164.8 0.0 2.8e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 KFP11870.1 - 2.8e-13 50.2 0.3 1e-11 45.1 0.0 2.4 2 0 0 2 2 2 1 THUMP domain Methyltransf_25 PF13649.6 KFP11870.1 - 0.0001 22.9 0.0 0.00034 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KFP11870.1 - 0.0016 18.0 0.4 0.0048 16.4 0.0 2.0 2 1 1 3 3 3 1 RRNA methyltransferase AviRa MTS PF05175.14 KFP11870.1 - 0.015 14.9 0.0 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KFP11870.1 - 0.043 14.5 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Fer4_NifH PF00142.18 KFP11870.1 - 0.091 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family BSP_II PF05432.11 KFP11870.1 - 0.095 12.4 19.3 0.14 11.9 19.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RhoGAP PF00620.27 KFP11871.1 - 1.6e-48 164.4 0.0 5.6e-48 162.6 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KFP11871.1 - 2.7e-19 69.2 5.0 1.1e-18 67.2 5.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP11871.1 - 3.1e-11 42.7 0.0 1.3e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP11871.1 - 1.9e-10 40.3 0.0 4.8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP11871.1 - 1.2e-09 37.9 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flg_hook PF02120.16 KFP11871.1 - 0.074 12.9 0.3 0.19 11.6 0.3 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK FlaC_arch PF05377.11 KFP11871.1 - 1.7 9.1 8.7 0.19 12.1 0.6 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Dad3 PF08656.10 KFP11871.1 - 2.1 8.5 5.9 4.6 7.4 1.1 3.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 TolA_bind_tri PF16331.5 KFP11871.1 - 4.4 7.5 10.9 1.9 8.6 2.6 3.3 2 0 0 2 2 2 0 TolA binding protein trimerisation SAP PF02037.27 KFP11872.1 - 6.9e-11 41.6 0.4 1.4e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 KFP11872.1 - 6.1e-09 35.6 8.8 6.1e-09 35.6 8.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP11872.1 - 4.5e-07 29.6 10.2 4.5e-07 29.6 10.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP11872.1 - 1.5e-05 24.7 10.2 1.7e-05 24.6 5.9 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KFP11872.1 - 5.8e-05 22.9 9.3 5.8e-05 22.9 9.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP11872.1 - 0.0001 22.5 16.8 0.00017 21.9 12.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP11872.1 - 0.0018 18.3 10.4 0.0018 18.3 10.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP11872.1 - 0.0025 17.7 13.3 0.0025 17.7 13.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain AKAP95 PF04988.12 KFP11872.1 - 0.0077 16.5 13.1 0.041 14.1 2.0 2.9 1 1 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-WRNIP1_ubi PF18279.1 KFP11872.1 - 0.0087 16.6 4.4 0.019 15.5 0.0 2.9 2 0 0 2 2 2 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-rbx1 PF12678.7 KFP11872.1 - 0.02 15.1 8.0 0.02 15.1 8.0 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain GAT PF03127.14 KFP11872.1 - 0.1 12.9 5.8 0.23 11.8 0.0 3.1 4 0 0 4 4 4 0 GAT domain Imm63 PF15599.6 KFP11872.1 - 0.11 12.9 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 63 HSR PF03172.13 KFP11872.1 - 0.12 12.5 1.0 0.49 10.6 0.2 2.3 2 1 1 3 3 3 0 HSR domain SPT16 PF08644.11 KFP11872.1 - 2.4 8.3 6.6 0.37 11.0 2.3 1.9 2 0 0 2 2 1 0 FACT complex subunit (SPT16/CDC68) zf-C3HC4_4 PF15227.6 KFP11872.1 - 5.2 7.3 20.6 0.64 10.2 14.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFP11872.1 - 6.1 7.1 14.7 0.048 13.8 5.8 2.2 3 0 0 3 3 3 0 zinc RING finger of MSL2 Caveolin PF01146.17 KFP11873.1 - 1.1e-36 125.7 0.1 1.2e-36 125.6 0.1 1.0 1 0 0 1 1 1 1 Caveolin CCDC117 PF15810.5 KFP11873.1 - 0.056 13.7 0.6 0.072 13.4 0.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 cwf18 PF08315.12 KFP11873.1 - 0.18 12.5 0.2 0.2 12.3 0.2 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor PET PF06297.14 KFP11874.1 - 2.2e-17 63.1 2.4 8.3e-09 35.6 0.1 2.7 2 1 1 3 3 3 2 PET Domain LIM PF00412.22 KFP11874.1 - 3.3e-08 33.6 0.2 3.3e-08 33.6 0.2 2.3 2 1 0 2 2 2 1 LIM domain ANF_receptor PF01094.28 KFP11875.1 - 1.5e-64 218.3 0.0 2.6e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP11875.1 - 2.1e-61 207.7 14.9 2.9e-61 207.2 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP11875.1 - 2.6e-13 49.7 11.1 5e-13 48.8 11.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP11875.1 - 0.0019 17.9 0.0 0.0089 15.7 0.0 1.9 1 1 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KFP11876.1 - 1.4e-21 77.0 0.0 1.5e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Haem_degrading PF03928.14 KFP11876.1 - 0.063 13.3 0.1 0.093 12.8 0.0 1.4 2 0 0 2 2 2 0 Haem-degrading EamA PF00892.20 KFP11877.1 - 8e-16 58.4 29.8 3.2e-08 33.8 6.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family LGFP PF08310.11 KFP11877.1 - 0.13 12.8 0.0 9 6.9 0.0 2.4 2 0 0 2 2 2 0 LGFP repeat STAG PF08514.11 KFP11878.1 - 6.8e-40 135.5 0.1 7.6e-40 135.3 0.1 1.0 1 0 0 1 1 1 1 STAG domain SRCR PF00530.18 KFP11879.1 - 7.4e-128 417.9 42.6 1.1e-32 112.5 3.6 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP11879.1 - 2.8e-19 69.5 13.6 0.00037 21.0 0.1 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP11879.1 - 2.4e-07 31.2 7.6 0.41 11.2 0.1 4.4 4 0 0 4 4 4 4 Hepsin, SRCR domain PEP-utilizers PF00391.23 KFP11879.1 - 0.089 12.5 0.0 6.5 6.6 0.0 3.1 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain TYW3 PF02676.14 KFP11879.1 - 1 8.6 8.9 27 4.0 0.1 4.0 4 0 0 4 4 4 0 Methyltransferase TYW3 M-inducer_phosp PF06617.13 KFP11880.1 - 4.2e-66 223.0 9.6 4.2e-66 223.0 9.6 1.5 2 0 0 2 2 2 1 M-phase inducer phosphatase Rhodanese PF00581.20 KFP11880.1 - 5.3e-13 49.4 0.0 1.5e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain CAF20 PF17052.5 KFP11880.1 - 0.085 13.0 2.5 4.4 7.4 0.1 2.8 3 0 0 3 3 3 0 Cap associated factor Tubulin-binding PF00418.19 KFP11883.1 - 6.7e-50 166.8 22.7 2.2e-17 62.8 4.8 3.1 3 0 0 3 3 3 3 Tau and MAP protein, tubulin-binding repeat HA2 PF04408.23 KFP11884.1 - 3e-14 53.2 0.0 8.7e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFP11884.1 - 2.1e-13 50.6 0.0 4.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KFP11884.1 - 4.2e-11 43.4 2.3 8e-06 26.5 0.6 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KFP11884.1 - 6.2e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFP11884.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 KFP11884.1 - 9.4e-05 22.5 0.3 0.026 14.7 0.1 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain AAA_19 PF13245.6 KFP11884.1 - 0.029 14.7 0.0 0.091 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFP11884.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFP11884.1 - 0.06 12.8 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KFP11884.1 - 0.16 12.5 0.0 0.61 10.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF5343 PF17278.2 KFP11884.1 - 0.18 11.9 0.0 28 4.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5343) AAA_23 PF13476.6 KFP11884.1 - 0.23 11.9 0.0 0.48 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain GHBP PF12772.7 KFP11885.1 - 3.2e-134 447.2 9.7 3.9e-134 446.9 9.7 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.10 KFP11885.1 - 1.7e-12 47.4 2.9 1.7e-12 47.4 2.9 2.7 4 0 0 4 4 4 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFP11885.1 - 5.9e-07 29.7 0.2 1.3e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Nab6_mRNP_bdg PF10567.9 KFP11885.1 - 0.075 12.5 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 RNA-recognition motif SelP_N PF04592.14 KFP11886.1 - 4.8e-44 150.5 14.8 5.2e-44 150.4 14.8 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Macoilin PF09726.9 KFP11886.1 - 0.2 10.1 5.4 0.23 10.0 5.4 1.0 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 KFP11886.1 - 2.1 7.5 5.9 2 7.5 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.7 KFP11886.1 - 7.7 5.9 19.1 8.3 5.8 19.1 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family BTB PF00651.31 KFP11887.1 - 1.7e-24 86.2 0.5 4.5e-24 84.8 0.5 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP11887.1 - 8.5e-15 54.4 50.5 2.7e-07 30.7 6.2 7.5 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP11887.1 - 2.3e-11 43.5 53.7 0.017 15.6 0.2 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11887.1 - 1.3e-10 41.2 61.0 0.022 15.6 0.3 7.0 7 0 0 7 7 6 6 C2H2-type zinc finger zf-met PF12874.7 KFP11887.1 - 1.9e-06 28.1 5.6 0.00028 21.2 0.9 6.6 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP11887.1 - 0.00025 21.0 46.4 0.0083 16.1 1.8 6.7 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP11887.1 - 0.0064 16.7 0.4 0.0064 16.7 0.4 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFP11887.1 - 0.013 15.3 1.8 2.5 8.0 0.0 3.7 3 0 0 3 3 3 0 GAGA factor zf_UBZ PF18439.1 KFP11887.1 - 0.3 10.7 23.4 2.7 7.6 0.1 5.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-AD PF07776.15 KFP11887.1 - 0.76 10.1 14.0 1.7 8.9 0.1 4.3 5 0 0 5 5 4 0 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.10 KFP11887.1 - 0.93 9.7 25.3 1.7 8.8 3.6 4.7 3 2 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KFP11887.1 - 1.1 10.1 20.1 10 6.9 2.3 3.9 2 1 1 3 3 3 0 zinc-ribbon family zf-C2H2_2 PF12756.7 KFP11887.1 - 5.2 7.5 36.4 4.3 7.7 2.2 6.5 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 KFP11888.1 - 3.3e-70 236.5 0.0 4.6e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11888.1 - 1.6e-39 135.7 0.0 2.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP11888.1 - 7.9e-10 38.5 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP11888.1 - 0.00046 19.9 0.1 0.00075 19.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP11888.1 - 0.0039 16.6 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IFN-gamma PF00714.17 KFP11888.1 - 0.077 12.8 0.4 0.43 10.4 0.0 2.2 1 1 1 2 2 2 0 Interferon gamma FlgM PF04316.13 KFP11888.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM HMG_CoA_synt_C PF08540.10 KFP11889.1 - 1.1e-126 422.2 0.4 1.4e-126 421.8 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFP11889.1 - 3.7e-108 359.1 0.5 5.1e-108 358.6 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 KFP11889.1 - 0.003 17.4 0.1 0.0083 16.0 0.1 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Phage_holin_7_1 PF16081.5 KFP11889.1 - 0.04 14.1 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family YdjM PF04307.14 KFP11890.1 - 0.00035 19.9 9.0 0.0011 18.3 9.2 1.7 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF4520 PF15016.6 KFP11891.1 - 1.2e-34 118.3 0.0 3e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) DUF4524 PF15025.6 KFP11891.1 - 1.6e-29 102.6 0.0 2.7e-28 98.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4964 PF16334.5 KFP11891.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) MIF4G PF02854.19 KFP11892.1 - 1.9e-30 106.1 0.3 2.3e-30 105.8 0.3 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 KFP11892.1 - 0.0066 16.1 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region YebG PF07130.12 KFP11892.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 YebG protein FGF PF00167.18 KFP11893.1 - 5.8e-47 158.9 4.7 7.3e-47 158.6 4.7 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP11893.1 - 0.0002 21.5 0.1 0.00041 20.5 0.1 1.6 1 1 0 1 1 1 1 Fascin domain SR-25 PF10500.9 KFP11893.1 - 0.0039 16.8 1.5 0.0039 16.8 1.5 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PDCD9 PF07147.12 KFP11894.1 - 1.7e-132 442.8 0.0 1.9e-132 442.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) SpoU_methylase PF00588.19 KFP11895.1 - 8.4e-32 110.3 0.0 1.1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFP11895.1 - 2.2e-13 50.3 0.0 3.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding adh_short PF00106.25 KFP11896.1 - 1.8e-32 112.4 0.0 2.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP11896.1 - 2.5e-30 105.7 0.0 3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP11896.1 - 0.0029 17.6 0.0 0.0036 17.2 0.0 1.3 1 1 0 1 1 1 1 KR domain AP3D1 PF06375.11 KFP11897.1 - 0.48 10.7 12.5 0.93 9.7 2.0 2.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 GWT1 PF06423.12 KFP11898.1 - 1.4e-34 119.4 1.1 1.4e-34 119.4 1.1 2.5 3 0 0 3 3 3 1 GWT1 Myosin_head PF00063.21 KFP11899.1 - 3.7e-200 666.6 1.3 5e-200 666.2 1.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFP11899.1 - 0.00039 20.0 13.8 0.002 17.7 1.7 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP11899.1 - 0.0012 19.1 0.1 0.013 15.8 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP11899.1 - 0.0055 17.1 0.3 0.35 11.3 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain Microtub_bd PF16796.5 KFP11899.1 - 0.028 14.4 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding RecX PF02631.16 KFP11899.1 - 0.36 11.3 2.4 1 9.8 2.4 1.7 1 0 0 1 1 1 0 RecX family 7tm_1 PF00001.21 KFP11900.1 - 6.1e-27 94.6 18.6 7.1e-27 94.4 18.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MTABC_N PF16185.5 KFP11900.1 - 0.018 14.5 1.0 0.018 14.5 1.0 2.1 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF2418 PF10332.9 KFP11900.1 - 2.7 8.6 5.1 1.3 9.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Carb_anhydrase PF00194.21 KFP11901.1 - 6.6e-91 304.4 2.1 7.5e-91 304.2 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase UCH PF00443.29 KFP11902.1 - 4.9e-85 285.1 0.0 8.1e-85 284.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFP11902.1 - 4e-26 91.5 0.0 1.9e-25 89.3 0.0 2.3 1 1 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KFP11902.1 - 1.5e-14 54.3 0.0 8.1e-08 32.2 0.0 3.5 2 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.32 KFP11902.1 - 4.9e-09 35.1 1.4 0.00059 19.2 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP11902.1 - 5e-09 35.4 1.2 0.024 14.5 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFP11902.1 - 5.5e-09 36.4 1.1 3.8e-06 27.3 0.3 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP11902.1 - 1.8e-08 33.5 3.4 0.00014 21.2 0.1 2.7 2 0 0 2 2 2 2 EF hand Ubiquitin_3 PF14836.6 KFP11902.1 - 1.4e-05 24.9 0.2 3.4e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KFP11902.1 - 7.7e-05 23.1 1.5 0.003 18.0 0.3 2.8 2 0 0 2 2 2 1 Ubiquitin-like domain EF-hand_8 PF13833.6 KFP11902.1 - 0.00011 21.9 6.3 0.26 11.2 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair TPR_10 PF13374.6 KFP11903.1 - 5e-24 83.4 4.9 1.4e-08 34.3 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP11903.1 - 3.3e-23 81.7 22.1 5.7e-10 39.3 0.8 7.1 4 3 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFP11903.1 - 7.8e-09 35.0 2.6 0.0018 18.2 0.1 5.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP11903.1 - 3.4e-06 26.6 22.1 0.00035 20.3 0.2 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP11903.1 - 4.7e-05 23.3 17.3 0.042 14.1 0.3 7.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP11903.1 - 5.3e-05 23.0 13.4 7.8 6.9 0.3 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP11903.1 - 0.0011 18.4 10.6 0.087 12.2 2.1 3.3 1 1 2 3 3 3 3 MalT-like TPR region PP2C PF00481.21 KFP11904.1 - 8e-61 205.9 0.0 1.2e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP11904.1 - 0.16 11.6 0.0 1.1 8.9 0.0 2.1 2 1 0 2 2 2 0 Protein phosphatase 2C BCAS3 PF12490.8 KFP11905.1 - 2.2e-29 102.7 0.0 3.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 KFP11905.1 - 0.0001 23.0 1.3 0.02 15.7 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat CTP_transf_1 PF01148.20 KFP11905.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family T-box PF00907.22 KFP11906.1 - 1.7e-17 64.3 0.1 2.7e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 T-box Helicase_C_2 PF13307.6 KFP11907.1 - 8.4e-54 182.3 0.0 1.9e-53 181.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFP11907.1 - 2.7e-49 167.1 0.2 2.7e-49 167.1 0.2 2.9 3 0 0 3 3 3 1 DEAD_2 DEAD PF00270.29 KFP11907.1 - 1.7e-06 27.9 0.0 6.6e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase HBB PF06777.11 KFP11907.1 - 0.00032 20.4 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 KFP11907.1 - 0.00045 20.3 0.1 0.15 12.1 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit INTS2 PF14750.6 KFP11908.1 - 0 1418.1 18.5 0 1417.9 18.5 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Vitellogenin_N PF01347.22 KFP11908.1 - 0.0023 16.4 0.0 0.0037 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region Med13_C PF06333.12 KFP11909.1 - 1.5e-117 392.5 0.1 1.5e-117 392.5 0.1 4.3 5 1 1 6 6 6 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KFP11909.1 - 6.5e-98 327.4 4.0 6.5e-98 327.4 4.0 3.2 3 1 0 3 3 3 1 MID domain of medPIWI Med13_N PF11597.8 KFP11909.1 - 2.6e-25 89.5 0.0 6.9e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal zf-C3HC4_3 PF13920.6 KFP11910.1 - 2e-10 40.3 7.1 3.6e-10 39.5 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP11910.1 - 1.5e-09 38.0 11.0 3.5e-09 36.8 11.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP11910.1 - 4.7e-09 35.9 10.6 8.7e-09 35.1 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP11910.1 - 6.2e-09 35.7 7.7 1.3e-08 34.7 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP11910.1 - 5e-08 32.7 11.2 1.1e-07 31.6 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP11910.1 - 2.4e-07 30.5 8.5 4.3e-07 29.7 8.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP11910.1 - 3e-07 30.3 9.3 7.2e-07 29.1 9.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP11910.1 - 4.6e-07 30.0 10.0 1e-06 28.9 10.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP11910.1 - 1.2e-05 25.4 10.9 2.4e-05 24.4 10.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFP11910.1 - 0.002 18.0 3.2 0.0043 16.9 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFP11910.1 - 0.023 14.8 7.6 0.57 10.3 7.6 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP11910.1 - 0.091 12.4 5.7 0.18 11.4 5.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type GAGA PF09237.11 KFP11910.1 - 0.18 11.6 1.5 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 GAGA factor zf-RING_11 PF17123.5 KFP11910.1 - 1.6 8.5 8.5 4 7.3 8.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 KFP11910.1 - 1.9 8.3 7.5 3.5 7.5 7.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CTU2 PF10288.9 KFP11910.1 - 2.5 8.4 5.7 49 4.2 5.7 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DZR PF12773.7 KFP11910.1 - 2.7 8.1 8.0 6.5 6.9 8.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon Macoilin PF09726.9 KFP11910.1 - 4 5.9 8.3 5.7 5.4 8.3 1.1 1 0 0 1 1 1 0 Macoilin family zf-C3HC4_5 PF17121.5 KFP11910.1 - 5.6 6.9 9.4 97 3.0 9.4 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFP11910.1 - 8.5 6.3 10.6 45 3.9 10.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 KFP11911.1 - 7.2e-70 235.4 0.0 1.3e-69 234.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11911.1 - 5.2e-37 127.5 0.0 6.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFP11911.1 - 3e-10 40.6 3.7 7.4e-10 39.4 3.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP11911.1 - 2e-07 30.6 0.0 6.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP11911.1 - 0.00018 20.4 0.1 0.00028 19.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP11911.1 - 0.036 13.7 0.1 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP11911.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP11911.1 - 0.19 10.6 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFP11911.1 - 0.25 10.7 0.2 0.4 10.0 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTH2 PF01981.16 KFP11912.1 - 1.6e-48 163.8 0.0 1.9e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2000 PF09391.10 KFP11912.1 - 0.038 13.9 0.3 0.7 9.8 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) Clathrin PF00637.20 KFP11913.1 - 1.3e-208 683.2 39.9 1.8e-34 118.7 1.4 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFP11913.1 - 3e-50 166.2 3.1 3.1e-08 33.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFP11913.1 - 1.1e-32 111.7 0.4 7.1e-32 109.1 0.3 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 KFP11913.1 - 1e-14 53.5 0.7 3.1e-14 52.0 0.7 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFP11913.1 - 1.6e-07 30.8 4.8 1.4e-05 24.4 0.3 4.0 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.6 KFP11913.1 - 0.00011 22.0 11.4 1.5 9.1 0.1 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP11913.1 - 0.00045 20.7 3.9 4.1 8.0 0.1 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP11913.1 - 0.00097 18.9 7.2 0.27 11.1 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP11913.1 - 0.0049 16.9 8.9 4.5 7.6 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP11913.1 - 0.016 16.0 22.5 24 6.1 0.0 9.2 8 1 1 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP11913.1 - 0.04 14.1 3.1 12 6.2 0.1 5.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Ovate PF04844.13 KFP11913.1 - 0.28 11.2 1.6 1.4 9.0 0.0 2.9 3 0 0 3 3 3 0 Transcriptional repressor, ovate HA2 PF04408.23 KFP11914.1 - 6.6e-15 55.3 0.0 1.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP11914.1 - 5.4e-14 52.3 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP11914.1 - 1.8e-12 47.6 0.0 3.9e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4685 PF15737.5 KFP11914.1 - 8.8e-05 22.9 1.0 0.1 13.1 0.3 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4685) DEAD PF00270.29 KFP11914.1 - 0.00054 19.8 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SesA PF17107.5 KFP11914.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Vicilin_N PF04702.12 KFP11914.1 - 0.15 11.9 1.8 0.33 10.8 1.8 1.4 1 0 0 1 1 1 0 Vicilin N terminal region Yippee-Mis18 PF03226.14 KFP11915.1 - 1.1e-12 48.0 0.2 1.5e-12 47.7 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.6 KFP11915.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp RIG-I_C-RD PF11648.8 KFP11915.1 - 0.034 14.4 0.4 0.069 13.4 0.4 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.13 KFP11915.1 - 0.072 13.6 2.4 0.26 11.8 0.5 2.0 1 1 0 2 2 2 0 Erv1 / Alr family zf-CHY PF05495.12 KFP11915.1 - 0.094 13.2 7.3 0.41 11.2 7.3 1.9 1 1 0 1 1 1 0 CHY zinc finger Elf1 PF05129.13 KFP11915.1 - 0.1 12.7 0.9 4.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like GDPD PF03009.17 KFP11916.1 - 1.2e-29 103.8 0.3 3.8e-22 79.3 0.1 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KFP11916.1 - 0.0042 17.5 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 KFP11916.1 - 0.013 15.1 0.1 0.068 12.8 0.1 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain DUF4954 PF16314.5 KFP11916.1 - 0.1 10.7 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Smg8_Smg9 PF10220.9 KFP11917.1 - 0 1056.6 0.0 0 1056.5 0.0 1.0 1 0 0 1 1 1 1 Smg8_Smg9 SKA2 PF16740.5 KFP11919.1 - 1.6e-29 101.8 2.2 1.8e-29 101.7 2.2 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 zf-B_box PF00643.24 KFP11920.1 - 6.3e-09 35.8 8.7 6.3e-09 35.8 8.7 2.9 2 1 1 3 3 2 1 B-box zinc finger MATH PF00917.26 KFP11920.1 - 2.7e-08 33.9 0.0 8.3e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 KFP11920.1 - 1.8e-05 24.5 15.1 1.8e-05 24.5 15.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP11920.1 - 0.0032 17.3 17.1 0.0032 17.3 17.1 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) HlyD_2 PF12700.7 KFP11920.1 - 0.01 14.6 4.7 0.019 13.7 4.7 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Baculo_PEP_C PF04513.12 KFP11920.1 - 0.052 13.6 5.1 0.99 9.4 2.0 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFP11920.1 - 0.12 10.8 2.8 0.24 9.9 2.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family MRFAP1 PF15155.6 KFP11920.1 - 0.16 12.5 3.6 0.15 12.6 1.4 2.1 2 0 0 2 2 2 0 MORF4 family-associated protein1 HTH_1 PF00126.27 KFP11920.1 - 0.41 10.6 1.7 4.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF148 PF02520.17 KFP11920.1 - 0.45 10.6 8.6 0.73 10.0 2.0 3.1 3 1 0 3 3 3 0 Domain of unknown function DUF148 PIN_8 PF18476.1 KFP11920.1 - 0.73 9.6 8.0 0.1 12.4 1.4 2.6 3 0 0 3 3 3 0 PIN like domain DUF2203 PF09969.9 KFP11920.1 - 1.1 10.0 4.8 31 5.3 2.9 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5071 PF16804.5 KFP11920.1 - 2.2 8.6 5.2 2.2 8.6 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5071) Spc7 PF08317.11 KFP11920.1 - 2.5 6.9 14.4 32 3.3 11.5 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFP11920.1 - 8.8 6.4 11.3 11 6.0 4.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PP2C PF00481.21 KFP11921.1 - 5.7e-64 216.2 0.2 7.2e-64 215.9 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP11921.1 - 0.0019 17.9 0.2 0.0058 16.3 0.2 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFP11921.1 - 0.0058 16.6 0.9 0.93 9.4 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Rad51 PF08423.11 KFP11922.1 - 3.4e-45 154.3 0.0 6e-45 153.5 0.0 1.3 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFP11922.1 - 2.1e-07 30.7 0.1 5.7e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFP11922.1 - 5.5e-05 22.6 0.1 0.00011 21.7 0.1 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 KFP11922.1 - 0.00011 21.8 0.2 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFP11922.1 - 0.00099 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFP11922.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP11922.1 - 0.013 16.0 0.1 0.036 14.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFP11922.1 - 0.04 14.2 0.2 0.52 10.6 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 KFP11922.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KFP11922.1 - 0.095 12.6 0.1 0.22 11.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KFP11922.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFP11922.1 - 0.17 12.3 0.0 0.48 10.8 0.0 1.7 2 0 0 2 2 2 0 RNA helicase 7tm_1 PF00001.21 KFP11923.1 - 2.4e-45 154.9 11.6 3.1e-45 154.6 11.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11923.1 - 6.1e-08 32.7 5.8 8.9e-05 22.3 1.0 2.1 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP11923.1 - 2.8e-07 30.2 10.4 3.9e-07 29.7 10.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP11923.1 - 3.5e-06 26.6 9.7 0.003 17.0 0.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP11923.1 - 0.0003 20.2 5.5 0.0003 20.2 5.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF4407 PF14362.6 KFP11923.1 - 1.9 7.8 3.8 12 5.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF2569 PF10754.9 KFP11923.1 - 5.8 7.4 12.6 12 6.3 4.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) FAM101 PF15068.6 KFP11924.1 - 2e-71 240.2 3.1 2.2e-71 240.1 3.1 1.0 1 0 0 1 1 1 1 FAM101 family Vps53_N PF04100.12 KFP11925.1 - 2.6e-171 569.7 0.4 4.5e-171 569.0 0.4 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KFP11925.1 - 1.7e-07 30.8 1.8 1.7e-07 30.8 1.8 2.1 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 KFP11925.1 - 4.2e-05 22.6 3.5 9.3e-05 21.5 3.5 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein VPS53_C PF16854.5 KFP11925.1 - 0.00052 19.9 5.2 0.001 19.0 0.0 3.0 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Laminin_II PF06009.12 KFP11925.1 - 0.0038 17.3 4.8 0.007 16.4 3.4 2.1 2 0 0 2 2 2 1 Laminin Domain II Sec8_exocyst PF04048.14 KFP11925.1 - 0.012 15.5 2.5 0.015 15.2 1.0 2.0 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 KFP11925.1 - 0.015 15.1 1.6 0.021 14.6 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function C-terminus (DUF2451) DUF4413 PF14372.6 KFP11925.1 - 0.017 15.5 0.2 0.19 12.1 0.0 2.9 3 1 0 3 3 2 0 Domain of unknown function (DUF4413) NBD94 PF16830.5 KFP11925.1 - 0.023 15.1 3.9 0.068 13.6 3.9 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH LXG PF04740.12 KFP11925.1 - 0.039 13.7 2.8 0.13 12.0 2.8 1.8 1 1 0 1 1 1 0 LXG domain of WXG superfamily Vps51 PF08700.11 KFP11925.1 - 0.043 13.9 5.6 0.086 12.9 1.5 3.3 2 1 1 3 3 2 0 Vps51/Vps67 GrpE PF01025.19 KFP11925.1 - 0.046 13.4 2.1 0.14 11.8 2.1 1.9 1 0 0 1 1 1 0 GrpE MCPsignal PF00015.21 KFP11925.1 - 0.086 12.7 1.0 0.31 10.9 1.0 1.9 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 KFP11925.1 - 0.089 12.7 2.4 0.31 10.9 1.6 2.3 2 0 0 2 2 2 0 Sec34-like family ATG16 PF08614.11 KFP11925.1 - 0.11 12.7 1.6 0.41 10.9 1.6 2.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KFP11925.1 - 0.13 12.3 11.0 4.3 7.4 6.0 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KFP11925.1 - 0.21 11.6 4.5 0.77 9.9 4.5 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.20 KFP11925.1 - 0.24 10.8 6.5 0.049 13.0 1.4 2.3 3 0 0 3 3 3 0 Tropomyosin COG5 PF10392.9 KFP11925.1 - 0.26 11.5 2.6 0.32 11.2 0.9 2.1 2 0 0 2 2 1 0 Golgi transport complex subunit 5 Syntaxin_2 PF14523.6 KFP11925.1 - 0.47 10.9 5.7 8.1 6.9 5.8 3.0 1 1 0 1 1 1 0 Syntaxin-like protein BLOC1_2 PF10046.9 KFP11925.1 - 0.56 10.5 5.6 1.8 8.9 2.3 3.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 KFP11925.1 - 0.62 10.3 10.4 0.058 13.6 2.7 2.9 3 0 0 3 3 2 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 KFP11925.1 - 0.68 10.2 8.3 0.27 11.5 3.1 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CREPT PF16566.5 KFP11925.1 - 1.5 9.0 7.2 1.8 8.7 1.5 3.4 3 1 1 4 4 3 0 Cell-cycle alteration and expression-elevated protein in tumour COG2 PF06148.11 KFP11925.1 - 1.5 8.9 5.8 2.4 8.2 2.9 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Snf7 PF03357.21 KFP11925.1 - 1.9 8.1 10.4 0.51 9.9 5.6 2.5 2 0 0 2 2 2 0 Snf7 ING PF12998.7 KFP11925.1 - 2.7 8.6 9.9 0.26 11.9 4.2 2.4 3 0 0 3 3 1 0 Inhibitor of growth proteins N-terminal histone-binding Prefoldin PF02996.17 KFP11925.1 - 3.1 7.8 7.5 18 5.3 1.5 3.6 2 1 2 4 4 4 0 Prefoldin subunit TRAM_LAG1_CLN8 PF03798.16 KFP11926.1 - 1.5e-40 139.0 16.1 1.7e-40 138.9 16.1 1.0 1 0 0 1 1 1 1 TLC domain Glyoxalase PF00903.25 KFP11928.1 - 0.00074 19.7 0.0 0.0051 17.0 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFP11928.1 - 0.005 17.6 0.0 5.5 7.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFP11928.1 - 0.079 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SpoU_methylase PF00588.19 KFP11929.1 - 7.5e-22 78.0 0.0 3.1e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFP11929.1 - 0.005 17.1 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Thioredoxin_8 PF13905.6 KFP11930.1 - 4e-33 113.6 0.0 8.3e-29 99.8 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP11930.1 - 1.2e-11 45.0 0.0 2.9e-08 34.1 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFP11930.1 - 1.3e-08 34.8 0.0 6.8e-05 22.8 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KFP11930.1 - 4.8e-08 33.1 0.0 4.2e-07 30.1 0.0 2.4 4 0 0 4 4 4 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFP11930.1 - 6.4e-08 32.6 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP11930.1 - 2.1e-06 27.5 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KFP11930.1 - 2.8e-05 24.2 0.0 0.00058 20.0 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like SCO1-SenC PF02630.14 KFP11930.1 - 4.5e-05 23.4 0.0 0.00023 21.1 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC HyaE PF07449.11 KFP11930.1 - 0.00024 21.0 0.1 2.8 7.9 0.0 3.9 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KFP11930.1 - 0.00057 20.0 0.0 0.0065 16.7 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin MatE PF01554.18 KFP11931.1 - 2.1e-53 180.3 28.9 2.7e-28 98.7 10.1 2.3 2 0 0 2 2 2 2 MatE MatE PF01554.18 KFP11932.1 - 6.4e-55 185.2 33.0 3.5e-29 101.5 9.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFP11932.1 - 3.1e-05 24.1 26.3 8.1e-05 22.7 13.8 3.5 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Aldedh PF00171.22 KFP11933.1 - 8.6e-86 288.3 0.0 9.9e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 KFP11934.1 - 2.1e-64 217.4 0.2 6e-64 216.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP11934.1 - 5.4e-44 150.4 0.0 9.7e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KFP11934.1 - 2e-25 89.7 3.1 3.7e-25 88.8 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 KFP11934.1 - 2.4e-07 30.3 0.0 6.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP11934.1 - 7.6e-05 22.4 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFP11934.1 - 0.00031 19.6 0.0 0.00052 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP11934.1 - 0.0045 16.3 0.0 0.019 14.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFP11934.1 - 0.0072 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 KFP11935.1 - 7.6e-58 191.1 27.4 5.3e-09 36.6 0.3 9.0 7 2 1 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP11935.1 - 1e-20 73.8 4.6 3.5e-06 27.2 0.1 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFP11935.1 - 7.2e-06 25.8 2.2 0.2 11.7 0.1 5.4 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KFP11935.1 - 2.4e-05 24.3 0.1 0.35 10.7 0.0 3.5 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP11935.1 - 0.0023 16.9 0.0 2.5 7.0 0.0 4.2 2 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP11935.1 - 0.0092 14.7 1.7 19 3.7 0.0 3.8 1 1 3 4 4 4 0 Nucleoporin Nup120/160 Frtz PF11768.8 KFP11935.1 - 0.016 13.5 0.0 3.4 5.9 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KFP11935.1 - 0.024 13.6 3.1 0.11 11.4 0.2 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KFP11935.1 - 0.038 12.7 0.6 8.2 5.0 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.6 KFP11935.1 - 0.071 12.4 0.9 24 4.1 0.1 4.0 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KFP11935.1 - 0.15 11.4 0.0 28 3.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain VID27 PF08553.10 KFP11935.1 - 0.2 10.7 0.0 8.6 5.3 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain RGS PF00615.19 KFP11936.1 - 4.7e-31 107.5 2.0 2.9e-12 46.9 0.1 3.5 3 0 0 3 3 3 3 Regulator of G protein signaling domain L_HMGIC_fpl PF10242.9 KFP11937.1 - 4.6e-14 53.0 0.5 5.7e-14 52.7 0.5 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF1240 PF06836.12 KFP11937.1 - 0.069 13.7 0.2 0.086 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Claudin_2 PF13903.6 KFP11937.1 - 0.088 12.6 0.4 0.097 12.4 0.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction AstE_AspA PF04952.14 KFP11938.1 - 2.9e-61 207.1 0.0 3.3e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Ank_2 PF12796.7 KFP11939.1 - 6.5e-19 68.3 5.6 1.3e-08 35.3 0.8 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP11939.1 - 7.8e-12 44.3 0.1 0.0058 17.0 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFP11939.1 - 1.2e-11 44.5 0.0 0.029 14.8 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP11939.1 - 1.8e-09 37.6 0.0 0.073 13.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP11939.1 - 6.3e-09 36.2 0.1 0.029 15.0 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFP11939.1 - 1.8e-08 33.9 18.2 3.1e-08 33.1 18.2 1.4 1 0 0 1 1 1 1 Ion transport protein DUF2070 PF09843.9 KFP11939.1 - 5.3 5.2 16.9 7.7 4.7 16.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FGGY_N PF00370.21 KFP11940.1 - 5e-22 78.7 0.2 2.1e-10 40.6 0.2 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFP11940.1 - 0.0055 16.2 0.0 0.009 15.5 0.0 1.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PQ-loop PF04193.14 KFP11941.1 - 1.3e-40 136.9 13.3 1.1e-20 73.1 1.7 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF4929 PF16283.5 KFP11941.1 - 0.015 14.3 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) FixG_C PF11614.8 KFP11941.1 - 0.074 13.3 0.3 1.7 8.9 0.1 2.1 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PDZ PF00595.24 KFP11942.1 - 3.5e-20 72.1 0.2 4.4e-20 71.8 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP11942.1 - 1.8e-11 44.2 0.3 2.5e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP11942.1 - 3.9e-11 42.6 0.1 7.2e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFP11942.1 - 0.13 12.6 0.1 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Rab5ip PF07019.12 KFP11943.1 - 8.7e-14 51.9 5.8 9.7e-14 51.7 5.8 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DMT_YdcZ PF04657.13 KFP11943.1 - 0.032 14.5 2.1 0.036 14.4 2.1 1.1 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ P2X_receptor PF00864.19 KFP11944.1 - 6e-165 548.8 0.2 6.9e-165 548.6 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor Ank_2 PF12796.7 KFP11945.1 - 9.6e-22 77.4 0.8 8.9e-11 42.2 0.1 4.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP11945.1 - 2.6e-13 48.8 0.2 7.2e-05 22.9 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KFP11945.1 - 3.1e-12 46.5 0.4 4.3e-05 23.7 0.1 4.5 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP11945.1 - 1.3e-11 44.7 0.2 0.0012 19.4 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFP11945.1 - 1.6e-10 40.6 23.1 2.7e-10 39.9 23.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 KFP11945.1 - 1.7e-10 40.9 0.2 0.00028 21.2 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat PKD_channel PF08016.12 KFP11945.1 - 0.0088 14.8 14.6 0.015 14.0 14.3 1.5 1 1 0 1 1 1 1 Polycystin cation channel NQRA_SLBB PF11973.8 KFP11946.1 - 2.6e-05 24.8 0.0 47 4.7 0.0 4.3 4 0 0 4 4 4 0 NQRA C-terminal domain Glyco_hydro_65C PF03633.15 KFP11946.1 - 8.6e-05 22.4 0.0 36 4.4 0.0 4.1 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain GATase1_like PF07090.11 KFP11946.1 - 0.1 12.0 0.1 1.6e+02 1.6 0.0 3.7 4 0 0 4 4 4 0 Putative glutamine amidotransferase VirB7 PF17413.2 KFP11946.1 - 0.19 11.1 1.5 1.8e+02 1.5 0.0 4.1 4 0 0 4 4 4 0 Outer membrane lipoprotein virB7 Aminotran_4 PF01063.19 KFP11946.1 - 6.9 6.5 5.0 2.9e+02 1.2 0.1 3.7 4 0 0 4 4 4 0 Amino-transferase class IV ubiquitin PF00240.23 KFP11947.1 - 1.2e-122 399.8 8.9 2.9e-31 107.0 0.1 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KFP11947.1 - 1.9e-54 181.4 9.5 2e-13 49.9 0.1 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFP11947.1 - 1.6e-23 82.9 2.1 0.00061 20.2 0.0 5.5 4 3 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KFP11947.1 - 4.4e-16 58.6 0.6 0.045 13.7 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFP11947.1 - 8.4e-11 42.1 1.7 0.41 11.0 0.0 4.1 4 0 0 4 4 4 3 Ubiquitin-like domain DUF2407 PF10302.9 KFP11947.1 - 4.5e-10 40.0 0.0 1.9 9.1 0.0 4.1 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 KFP11947.1 - 3.5e-08 33.0 0.1 0.44 9.8 0.0 3.1 3 0 0 3 3 3 3 RNA methyltransferase Sde2_N_Ubi PF13019.6 KFP11947.1 - 9.1e-08 32.1 0.0 0.84 9.4 0.0 3.7 1 1 3 4 4 4 3 Silencing defective 2 N-terminal ubiquitin domain Rad60-SLD_2 PF13881.6 KFP11947.1 - 1.1e-07 31.9 0.2 7.2 6.8 0.0 5.0 4 4 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like DUF3861 PF12977.7 KFP11947.1 - 5.2e-06 26.5 1.0 18 5.5 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 KFP11947.1 - 6.2e-06 26.3 0.7 6.1 7.0 0.0 3.9 4 0 0 4 4 4 3 UDP-glucose:Glycoprotein Glucosyltransferase RBD PF02196.15 KFP11947.1 - 1.5e-05 25.0 0.0 28 4.9 0.0 4.3 4 0 0 4 4 4 0 Raf-like Ras-binding domain TraK PF06586.11 KFP11947.1 - 3.8e-05 23.5 0.7 12 5.5 0.0 4.1 4 0 0 4 4 4 0 TraK protein GDYXXLXY PF14345.6 KFP11947.1 - 5.8e-05 22.9 0.6 23 4.7 0.0 4.2 4 0 0 4 4 4 0 GDYXXLXY protein DUF2170 PF09938.9 KFP11947.1 - 0.00027 20.6 0.1 12 5.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2170) DUF2870 PF11069.8 KFP11947.1 - 0.0019 18.5 0.0 1e+02 3.4 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 KFP11947.1 - 0.0022 18.0 14.3 72 3.5 0.0 7.0 7 1 1 8 8 7 0 Ubiquitin-like domain SQAPI PF16845.5 KFP11947.1 - 0.019 15.3 0.1 72 3.8 0.0 3.2 3 0 0 3 3 3 0 Aspartic acid proteinase inhibitor CorA PF01544.18 KFP11947.1 - 0.025 13.9 0.4 89 2.2 0.0 3.8 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein FlgD_ig PF13860.6 KFP11947.1 - 0.033 14.1 3.4 1.1e+02 2.8 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain TOBE_2 PF08402.10 KFP11947.1 - 0.06 13.5 0.0 1.3e+02 2.8 0.0 3.7 4 0 0 4 4 4 0 TOBE domain ProRS-C_2 PF09181.10 KFP11947.1 - 0.075 13.2 3.2 1.5e+02 2.6 0.0 4.0 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Lac_bphage_repr PF06543.12 KFP11947.1 - 0.13 12.3 0.2 3.2e+02 1.4 0.0 4.2 4 0 0 4 4 4 0 Lactococcus bacteriophage repressor Pullulanase_N2 PF17967.1 KFP11947.1 - 0.15 12.9 0.0 2.1e+02 2.8 0.0 3.3 3 0 0 3 3 3 0 Pullulanase N2 domain Big_7 PF17957.1 KFP11947.1 - 0.17 12.7 0.2 3.9e+02 1.9 0.0 3.8 4 0 0 4 4 4 0 Bacterial Ig domain LBP_C PF17386.2 KFP11947.1 - 1.1 9.3 2.8 2.8e+02 1.5 0.0 3.9 4 0 0 4 4 4 0 Lacto-N-biose phosphorylase C-terminal domain PI3K_p85B PF02192.16 KFP11947.1 - 6.6 6.6 6.9 2e+02 1.8 0.1 4.0 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain GFA PF04828.14 KFP11948.1 - 7e-10 39.1 1.3 7e-10 39.1 1.3 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme ASFV_p27 PF06556.11 KFP11948.1 - 0.052 13.7 0.2 0.084 13.0 0.2 1.3 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus PIG-L PF02585.17 KFP11949.1 - 6.2e-11 43.0 0.0 1.7e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase GPS2_interact PF15784.5 KFP11950.1 - 9.1e-36 122.2 4.9 9.1e-36 122.2 4.9 6.7 8 0 0 8 8 8 1 G-protein pathway suppressor 2-interacting domain Myb_DNA-binding PF00249.31 KFP11950.1 - 6.6e-17 61.4 0.3 2.1e-12 47.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP11950.1 - 0.0025 18.0 2.3 0.065 13.5 0.3 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_12 PF13424.6 KFP11951.1 - 1.2e-20 73.6 16.1 1.5e-12 47.6 0.5 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFP11951.1 - 3.4e-11 42.6 12.7 0.033 14.1 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP11951.1 - 7.6e-11 41.3 16.5 0.0033 17.4 0.4 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFP11951.1 - 8.8e-09 34.8 17.7 0.0054 16.5 0.6 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP11951.1 - 2.3e-08 33.6 14.1 0.034 14.3 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP11951.1 - 1.5e-07 31.1 12.8 7.2e-06 25.6 5.9 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 KFP11951.1 - 1.3e-06 28.7 12.1 0.33 11.9 0.4 5.3 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP11951.1 - 3.2e-06 26.8 9.5 0.029 14.4 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ComR_TPR PF18710.1 KFP11951.1 - 4.6e-06 26.3 5.0 4.6e-06 26.3 5.0 2.1 2 1 0 2 2 2 1 ComR tetratricopeptide TPR_19 PF14559.6 KFP11951.1 - 1.8e-05 25.1 17.9 0.0085 16.6 0.4 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP11951.1 - 6.8e-05 23.4 8.7 0.012 16.3 1.2 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP11951.1 - 0.0018 18.4 0.8 0.11 12.7 0.1 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP11951.1 - 0.0038 17.5 12.0 1.4 9.5 0.1 5.8 5 2 0 5 5 5 2 Tetratricopeptide repeat ANAPC5 PF12862.7 KFP11951.1 - 0.01 15.8 4.4 0.63 10.1 1.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_21 PF09976.9 KFP11951.1 - 0.022 14.5 15.2 0.45 10.2 7.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KFP11951.1 - 0.045 14.4 0.0 2.4 9.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 KFP11951.1 - 0.13 11.7 14.5 0.079 12.4 3.2 2.4 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP LsmAD PF06741.13 KFP11951.1 - 0.28 11.8 1.7 2.2 8.9 0.0 2.6 2 0 0 2 2 2 0 LsmAD domain Complex1_LYR_2 PF13233.6 KFP11951.1 - 2.3 9.0 5.9 6.2 7.7 5.8 1.9 1 1 0 1 1 1 0 Complex1_LYR-like 7tm_1 PF00001.21 KFP11953.1 - 9.6e-53 179.2 19.6 1.2e-52 178.9 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP11953.1 - 5e-13 49.4 19.7 6.6e-13 49.0 19.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP11953.1 - 6e-13 48.8 21.5 1.8e-11 43.9 21.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP11953.1 - 2.1e-06 27.6 18.3 2.1e-06 27.6 18.3 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GPR_Gpa2_C PF11970.8 KFP11953.1 - 0.0027 17.7 0.4 0.01 15.9 0.4 2.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term CH PF00307.31 KFP11954.1 - 7.2e-22 77.6 0.0 2.4e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP11954.1 - 6.1e-06 26.0 0.1 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain DUF5475 PF17569.2 KFP11954.1 - 0.0037 17.6 0.5 0.0097 16.2 0.5 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5475) DUF641 PF04859.12 KFP11954.1 - 0.029 14.7 0.6 0.029 14.7 0.6 6.7 4 2 3 7 7 7 0 Plant protein of unknown function (DUF641) Tim17 PF02466.19 KFP11955.1 - 3e-27 95.2 3.5 3.5e-27 95.0 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RhoGAP PF00620.27 KFP11956.1 - 2.8e-33 114.9 0.0 5.4e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFP11956.1 - 1.5e-10 41.5 3.0 1.1e-09 38.7 1.9 2.7 2 1 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFP11956.1 - 1.3e-09 38.6 1.0 1.8e-09 38.1 0.1 1.7 2 0 0 2 2 2 1 RhoGEF domain C2 PF00168.30 KFP11956.1 - 0.0028 17.9 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Phage_antiter_Q PF06323.11 KFP11956.1 - 0.0089 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Phage antitermination protein Q IQ_SEC7_PH PF16453.5 KFP11956.1 - 0.066 13.2 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 PH domain Tox-PL-2 PF15643.6 KFP11956.1 - 0.11 12.6 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Papain fold toxin 2 PH_10 PF15411.6 KFP11956.1 - 0.32 11.3 0.1 0.32 11.3 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain V-SNARE_C PF12352.8 KFP11957.1 - 6.6e-22 77.6 3.6 6.6e-22 77.6 3.6 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFP11957.1 - 0.0046 16.8 0.9 0.031 14.2 0.2 2.2 2 0 0 2 2 2 1 Sec20 DUF1664 PF07889.12 KFP11957.1 - 0.12 12.4 1.7 0.21 11.6 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Muted PF14942.6 KFP11957.1 - 0.21 11.9 4.8 1.6 9.1 2.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_M14 PF00246.24 KFP11958.1 - 8.5e-175 580.4 0.0 7.1e-85 285.3 0.0 3.1 3 0 0 3 3 3 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFP11958.1 - 2.6e-37 126.9 9.1 6.1e-13 48.9 0.5 3.4 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP11958.1 - 8.2e-21 73.8 2.8 3.5e-08 33.3 0.1 3.4 3 0 0 3 3 3 3 CarboxypepD_reg-like domain PEGA PF08308.11 KFP11958.1 - 7.3e-06 25.8 0.2 0.055 13.4 0.0 3.4 3 0 0 3 3 3 2 PEGA domain AstE_AspA PF04952.14 KFP11958.1 - 0.00079 18.6 0.1 0.024 13.7 0.0 2.5 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF3823 PF12866.7 KFP11958.1 - 0.0041 17.4 0.1 0.51 10.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3823) N-terminal domain fn3_3 PF14686.6 KFP11958.1 - 0.15 11.8 0.8 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II Ig_3 PF13927.6 KFP11959.1 - 4.6e-19 68.8 5.2 2e-14 54.0 1.6 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP11959.1 - 1.8e-18 66.5 3.8 7e-12 45.4 1.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP11959.1 - 5.7e-18 65.0 2.0 2.1e-12 47.2 0.5 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP11959.1 - 3.4e-16 59.1 1.3 1.7e-15 56.8 0.2 2.2 2 1 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.17 KFP11959.1 - 3.8e-11 43.1 6.6 6.7e-09 35.9 2.1 3.8 2 2 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP11959.1 - 9.4e-07 28.8 4.1 0.00016 21.6 0.9 3.0 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP11959.1 - 2.7e-05 24.4 4.5 0.0054 17.0 2.3 2.7 2 1 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP11959.1 - 0.00023 20.6 0.1 1 8.9 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP11959.1 - 0.0005 20.1 0.4 0.0056 16.7 0.2 2.2 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFP11959.1 - 0.0016 18.8 3.8 0.0099 16.3 1.1 2.8 2 2 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFP11959.1 - 0.023 14.7 0.1 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 C17orf99 Ig domain IgGFc_binding PF17517.2 KFP11959.1 - 0.038 13.3 2.1 0.57 9.4 0.9 2.1 1 1 1 2 2 2 0 IgGFc binding protein Adeno_E3_CR1 PF02440.15 KFP11959.1 - 0.062 13.1 3.9 0.11 12.3 2.6 2.0 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 Peptidase_C1_2 PF03051.15 KFP11960.1 - 1.7e-185 617.0 3.4 1.9e-185 616.8 3.4 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFP11960.1 - 0.00036 20.7 1.6 0.0067 16.5 0.2 2.8 3 0 0 3 3 3 1 Papain family cysteine protease SNF PF00209.18 KFP11961.1 - 4.1e-228 758.3 36.6 4.7e-228 758.1 36.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 5HT_transport_N PF03491.13 KFP11961.1 - 4.8e-06 26.7 1.9 1e-05 25.6 1.9 1.5 1 0 0 1 1 1 1 Serotonin (5-HT) neurotransmitter transporter, N-terminus PRONE PF03759.13 KFP11961.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) DUF2040 PF09745.9 KFP11962.1 - 5.2e-38 129.8 24.2 5.2e-38 129.8 24.2 5.7 2 1 4 6 6 6 1 Coiled-coil domain-containing protein 55 (DUF2040) DSPc PF00782.20 KFP11963.1 - 2.3e-34 118.0 0.0 9.1e-34 116.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 KFP11963.1 - 5.2e-11 42.3 5.1 1e-10 41.3 5.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 KFP11963.1 - 0.025 14.2 0.0 0.084 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HTH_Tnp_Tc5 PF03221.16 KFP11965.1 - 9.5e-18 64.0 0.4 1.9e-17 63.1 0.4 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KFP11965.1 - 8.2e-15 54.9 0.0 5.9e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 KFP11965.1 - 4.1e-06 26.3 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 KFP11965.1 - 0.00074 19.6 2.9 0.0017 18.5 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KFP11965.1 - 0.049 13.4 2.1 0.25 11.2 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KFP11965.1 - 0.075 13.4 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Transposase DARPP-32 PF05395.12 KFP11965.1 - 0.48 10.6 3.2 0.84 9.8 3.2 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 P5CR_dimer PF14748.6 KFP11966.1 - 1.2e-35 121.9 2.2 2e-35 121.1 2.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFP11966.1 - 2.3e-08 34.5 0.0 1.4e-07 32.0 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KFP11966.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KFP11966.1 - 0.054 13.1 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Keratin PF02422.16 KFP11968.1 - 1.3e-31 108.1 9.9 1.4e-31 108.0 9.9 1.0 1 0 0 1 1 1 1 Keratin CALCOCO1 PF07888.11 KFP11968.1 - 0.17 10.7 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tcp10_C PF07202.13 KFP11969.1 - 1.3e-86 289.0 6.7 1.4e-86 288.9 6.7 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DUF4176 PF13780.6 KFP11969.1 - 0.0079 16.2 0.2 0.12 12.4 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4176) GSHPx PF00255.19 KFP11969.1 - 0.045 13.3 0.1 0.098 12.2 0.1 1.6 1 1 0 1 1 1 0 Glutathione peroxidase Big_11 PF18200.1 KFP11969.1 - 0.077 12.9 1.6 1.2 9.1 0.3 2.8 1 1 2 3 3 3 0 Bacterial Ig-like domain potato_inhibit PF00280.18 KFP11969.1 - 0.18 12.5 1.2 32 5.3 0.0 3.4 3 1 1 4 4 4 0 Potato inhibitor I family UNC-93 PF05978.16 KFP11970.1 - 7.8e-11 41.9 9.5 7.8e-11 41.9 9.5 3.6 2 2 1 3 3 3 3 Ion channel regulatory protein UNC-93 RA PF00788.23 KFP11974.1 - 1.3e-46 157.1 0.0 2.1e-23 82.7 0.0 3.0 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 KFP11974.1 - 1.8e-30 105.3 4.1 2e-30 105.1 1.6 2.4 2 0 0 2 2 2 1 DIL domain PDZ PF00595.24 KFP11974.1 - 4.8e-17 62.1 0.6 1.1e-16 60.9 0.6 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP11974.1 - 2.3e-08 33.7 0.4 5.4e-08 32.6 0.4 1.7 1 0 0 1 1 1 1 PDZ domain FHA PF00498.26 KFP11974.1 - 1.3e-06 28.6 0.0 3.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain PDZ_2 PF13180.6 KFP11974.1 - 5e-05 23.5 0.4 0.00018 21.8 0.4 1.9 1 0 0 1 1 1 1 PDZ domain Yop-YscD_cpl PF16697.5 KFP11974.1 - 0.0085 16.4 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4477 PF14780.6 KFP11974.1 - 0.032 13.8 0.2 0.1 12.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Kinesin PF00225.23 KFP11975.1 - 1e-82 277.8 0.1 4.2e-47 160.7 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KFP11975.1 - 1.4e-41 141.9 0.0 4e-41 140.4 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding EBP50_C PF09007.11 KFP11975.1 - 0.3 12.1 7.7 2.8 8.9 0.4 2.4 2 0 0 2 2 2 0 EBP50, C-terminal Tup_N PF08581.10 KFP11975.1 - 1.3 9.4 6.8 2.4 8.5 5.6 2.1 1 1 1 2 2 2 0 Tup N-terminal Sulfotransfer_1 PF00685.27 KFP11978.1 - 3.1e-42 144.9 0.5 3.5e-42 144.7 0.5 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11978.1 - 1.9e-05 25.2 0.0 3.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Thyroglobulin_1 PF00086.18 KFP11979.1 - 1.2e-37 127.4 18.8 3e-19 68.4 4.5 2.9 2 0 0 2 2 2 2 Thyroglobulin type-1 repeat Thyroglob_assoc PF16597.5 KFP11979.1 - 3e-24 85.1 2.1 6.3e-24 84.1 2.1 1.6 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain SPARC_Ca_bdg PF10591.9 KFP11979.1 - 1.1e-11 45.1 0.1 3.1e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFP11979.1 - 1.8e-07 31.2 4.2 1.8e-07 31.2 4.2 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP11979.1 - 9.9e-06 25.9 0.1 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP11979.1 - 5.9e-05 22.3 0.2 1.4 8.7 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP11979.1 - 0.00014 21.5 0.3 1.5 9.0 0.1 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KFP11979.1 - 0.018 14.5 2.0 0.13 11.9 0.0 3.2 4 0 0 4 4 4 0 EF hand HSNSD PF12062.8 KFP11981.1 - 1.3e-248 825.7 0.1 1.7e-248 825.2 0.1 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFP11981.1 - 1.8e-42 145.7 0.0 2.9e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP11981.1 - 1.4e-08 35.5 0.1 0.00074 20.0 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family MT-A70 PF05063.14 KFP11982.1 - 2.9e-63 212.9 0.0 3.9e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 PDZ_6 PF17820.1 KFP11983.1 - 1.9e-07 30.8 0.0 4.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.11 KFP11983.1 - 6.3e-06 25.9 6.0 0.044 13.3 0.1 2.8 2 1 0 2 2 2 2 Calcineurin-binding protein (Calsarcin) PDZ PF00595.24 KFP11983.1 - 4e-05 23.9 0.0 8.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP11983.1 - 0.0063 16.8 0.0 0.042 14.2 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Calsarcin PF05556.11 KFP11984.1 - 2.3e-78 263.3 0.4 6.8e-78 261.7 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) UCH PF00443.29 KFP11985.1 - 4.9e-20 72.1 0.2 1.2e-19 70.8 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP11985.1 - 5.2e-08 32.9 5.2 5.2e-08 32.9 5.2 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Lipocalin PF00061.23 KFP11986.1 - 6.2e-17 62.1 1.7 6.6e-17 62.1 1.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP11986.1 - 2e-11 43.9 1.9 2.3e-11 43.7 1.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_4 PF13648.6 KFP11986.1 - 0.036 15.0 3.0 0.064 14.2 3.0 1.5 1 1 0 1 1 1 0 Lipocalin-like domain PDEase_I PF00233.19 KFP11987.1 - 3.7e-76 256.0 1.8 3.7e-76 256.0 1.8 2.4 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFP11987.1 - 1.5e-31 109.8 0.0 3.6e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFP11987.1 - 3e-07 30.8 0.0 0.0042 17.4 0.0 2.7 2 1 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFP11987.1 - 0.00083 19.7 0.1 5.4 7.4 0.0 4.5 4 2 0 4 4 4 1 GAF domain UTP15_C PF09384.10 KFP11987.1 - 0.013 15.2 0.3 0.79 9.4 0.1 2.7 2 0 0 2 2 2 0 UTP15 C terminal ATLF PF07737.11 KFP11987.1 - 0.092 12.0 2.5 0.13 11.5 1.2 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain zf_ZIC PF18366.1 KFP11987.1 - 0.31 11.2 2.7 40 4.4 0.2 3.6 3 1 1 4 4 4 0 Zic proteins zinc finger domain Ribosomal_L30 PF00327.20 KFP11988.1 - 5.6e-13 48.5 1.2 5.6e-13 48.5 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 KFP11988.1 - 5.3e-08 33.0 0.1 5.3e-08 33.0 0.1 2.1 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain HORMA PF02301.18 KFP11989.1 - 9e-11 41.8 0.1 1.6e-10 40.9 0.1 1.3 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KFP11989.1 - 0.032 14.2 0.5 0.078 13.0 0.1 1.7 2 0 0 2 2 2 0 Autophagy-related protein 101 ATG13 PF10033.9 KFP11989.1 - 0.042 13.5 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 DUF2791 PF10923.8 KFP11989.1 - 0.061 12.2 0.1 0.074 11.9 0.1 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) zf-H2C2_2 PF13465.6 KFP11990.1 - 9.4e-73 237.6 116.8 2.3e-10 40.4 0.6 17.0 17 0 0 17 17 17 13 Zinc-finger double domain zf-C2H2 PF00096.26 KFP11990.1 - 4.8e-72 234.6 109.6 1.6e-06 28.2 0.6 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP11990.1 - 9e-59 191.0 112.5 0.00018 22.1 0.2 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP11990.1 - 4.4e-36 122.4 96.5 7.5e-06 26.1 1.2 16.2 16 0 0 16 16 16 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP11990.1 - 3.8e-32 109.7 92.1 3.3e-05 24.1 2.4 15.7 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP11990.1 - 6.3e-27 93.0 105.8 0.001 19.0 0.6 16.7 15 2 1 16 16 16 11 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP11990.1 - 2.3e-19 68.8 60.6 0.0035 17.1 0.1 14.2 15 0 0 15 15 15 7 zinc-finger C2H2-type zf-Di19 PF05605.12 KFP11990.1 - 9.3e-11 41.9 80.8 0.0029 17.9 1.9 9.4 5 3 3 9 9 9 7 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP11990.1 - 1.2e-05 25.5 65.8 0.0006 20.1 2.0 8.7 1 1 7 9 9 9 3 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFP11990.1 - 3.5e-05 23.5 5.3 0.0026 17.5 0.3 14.6 15 2 0 15 15 14 3 C2H2-type zinc-finger domain zf_UBZ PF18439.1 KFP11990.1 - 0.00063 19.3 68.8 0.2 11.3 0.2 14.8 16 0 0 16 16 16 2 Ubiquitin-Binding Zinc Finger Trm112p PF03966.16 KFP11990.1 - 0.0025 18.4 13.5 0.091 13.4 0.2 5.5 3 2 1 4 4 3 1 Trm112p-like protein zf-C2H2_2 PF12756.7 KFP11990.1 - 0.0031 17.8 91.9 0.83 10.0 2.4 13.4 1 1 11 14 14 14 4 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP11990.1 - 0.0056 17.4 9.0 0.0056 17.4 9.0 8.0 1 1 5 6 6 6 1 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 KFP11990.1 - 0.015 15.6 23.1 5.4 7.4 0.1 7.4 4 3 2 7 7 7 0 BolA-like protein zf_C2H2_10 PF18414.1 KFP11990.1 - 0.086 12.4 12.0 2.5 7.7 0.0 5.6 5 0 0 5 5 5 0 C2H2 type zinc-finger FerB PF08150.12 KFP11990.1 - 0.24 12.0 0.6 2.3 8.9 0.3 2.9 1 1 1 2 2 2 0 FerB (NUC096) domain TRAF6_Z2 PF18048.1 KFP11990.1 - 0.38 10.9 0.1 0.38 10.9 0.1 7.6 9 0 0 9 9 8 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_15 PF17032.5 KFP11990.1 - 0.81 10.5 76.5 1.1 10.0 2.1 8.8 2 1 7 9 9 8 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFP11990.1 - 1.4 9.1 82.2 0.19 11.8 1.5 11.6 8 3 5 13 13 13 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KFP11990.1 - 2.9 8.2 45.5 3.4 8.0 0.1 11.1 12 1 0 12 12 12 0 zinc-ribbon zf-C2HC_2 PF13913.6 KFP11990.1 - 5.8 6.9 69.8 0.099 12.6 2.5 12.6 14 0 0 14 14 12 0 zinc-finger of a C2HC-type CC2-LZ PF16516.5 KFP11991.1 - 8.5e-14 51.7 13.6 8.5e-14 51.7 13.6 3.2 1 1 2 3 3 3 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KxDL PF10241.9 KFP11991.1 - 0.00036 20.7 4.7 0.00036 20.7 4.7 3.6 3 1 0 3 3 3 1 Uncharacterized conserved protein FlxA PF14282.6 KFP11991.1 - 0.0032 17.4 5.6 0.0032 17.4 5.6 3.0 2 1 1 3 3 3 1 FlxA-like protein HAUS-augmin3 PF14932.6 KFP11991.1 - 0.011 15.3 7.8 0.011 15.3 7.8 3.0 1 1 1 2 2 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 KFP11991.1 - 0.043 13.2 19.7 6.4 6.0 19.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KFP11991.1 - 0.13 12.7 3.5 2.9 8.4 0.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 KFP11991.1 - 0.44 10.3 40.4 1.6 8.5 40.4 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF2353 PF09789.9 KFP11991.1 - 0.98 8.7 32.7 1.5 8.1 32.5 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4047 PF13256.6 KFP11991.1 - 2.3 8.5 16.4 0.75 10.0 2.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) TPR_MLP1_2 PF07926.12 KFP11991.1 - 5.2 7.2 41.7 0.44 10.6 8.4 3.2 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KFP11991.1 - 6.3 6.8 44.6 36 4.4 12.5 3.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 7tm_1 PF00001.21 KFP11992.1 - 2.8e-51 174.4 22.1 3.7e-51 174.0 22.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP11992.1 - 4e-05 23.4 17.1 4e-05 23.4 17.1 2.4 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP11992.1 - 0.0011 18.4 25.5 0.0032 16.9 25.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP11992.1 - 0.014 15.1 23.3 0.12 12.0 23.3 2.2 1 1 0 1 1 1 0 Olfactory receptor Herpes_US9 PF06072.11 KFP11992.1 - 0.025 14.5 0.5 0.025 14.5 0.5 3.4 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 T4SS_CagC PF16943.5 KFP11992.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.7 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system CitMHS PF03600.16 KFP11992.1 - 0.52 9.5 13.8 1.9 7.6 13.5 1.9 1 1 1 2 2 2 0 Citrate transporter SBF2 PF12335.8 KFP11993.1 - 0.00012 21.8 2.3 0.00021 21.0 0.2 2.2 2 1 0 2 2 2 1 Myotubularin protein DUF1754 PF08555.10 KFP11993.1 - 1.5 9.6 10.9 0.089 13.6 2.1 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF3506 PF12014.8 KFP11994.1 - 0.00024 21.1 3.2 0.16 12.0 0.1 3.8 2 1 1 4 4 4 2 Domain of unknown function (DUF3506) Atg8 PF02991.16 KFP11995.1 - 1e-43 147.8 0.2 1.1e-43 147.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFP11995.1 - 1.8e-06 28.3 0.0 2.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad60-SLD PF11976.8 KFP11995.1 - 0.076 12.9 0.1 0.62 9.9 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_B559a PF00284.20 KFP11995.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit MORN PF02493.20 KFP11996.1 - 1.2e-41 138.2 67.9 9.1e-10 37.9 0.9 8.6 8 0 0 8 8 8 8 MORN repeat DUF4701 PF15773.5 KFP11999.1 - 1.6e-14 53.8 11.5 1.7e-14 53.7 11.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4701) Type2_restr_D3 PF16902.5 KFP11999.1 - 0.17 11.8 0.3 20 5.2 0.2 2.4 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Ank_2 PF12796.7 KFP12000.1 - 1.2e-34 118.7 0.5 8e-14 52.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP12000.1 - 4.4e-29 99.6 2.0 1.2e-05 25.6 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KFP12000.1 - 1.7e-27 92.4 0.2 4.9e-05 23.4 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 KFP12000.1 - 3.9e-23 81.2 0.6 3.2e-08 33.7 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP12000.1 - 4.3e-23 81.4 0.0 1.6e-08 34.9 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFP12000.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP12000.1 - 4.3e-12 46.0 0.0 9.2e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KFP12000.1 - 0.06 13.5 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 IGR protein motif YlqD PF11068.8 KFP12000.1 - 0.096 13.1 3.8 0.17 12.2 3.8 1.3 1 0 0 1 1 1 0 YlqD protein FH2 PF02181.23 KFP12000.1 - 0.33 10.0 1.7 0.56 9.3 1.7 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Cluap1 PF10234.9 KFP12001.1 - 1.3e-78 264.1 17.6 2e-78 263.5 17.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.12 KFP12001.1 - 3.4e-05 23.6 2.3 4.8e-05 23.1 2.3 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF4349 PF14257.6 KFP12001.1 - 0.19 11.1 5.9 0.39 10.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) RasGAP_C PF03836.15 KFP12001.1 - 0.28 11.3 11.2 0.76 9.9 11.2 1.8 1 1 0 1 1 1 0 RasGAP C-terminus LRR_6 PF13516.6 KFP12002.1 - 5.2e-52 169.5 30.0 1.9e-05 24.4 0.0 13.9 13 0 0 13 13 13 13 Leucine Rich repeat NACHT PF05729.12 KFP12002.1 - 1.3e-30 106.5 0.0 3.3e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KFP12002.1 - 4.6e-25 88.6 0.4 4.6e-25 88.6 0.4 2.2 2 0 0 2 2 2 1 NLRC4 helical domain HD2 NOD2_WH PF17779.1 KFP12002.1 - 1e-15 57.8 2.4 1.8e-15 57.0 1.1 2.3 2 0 0 2 2 2 1 NOD2 winged helix domain LRR_1 PF00560.33 KFP12002.1 - 1e-06 28.4 7.1 30 5.7 0.0 9.2 9 1 0 9 9 8 0 Leucine Rich Repeat LRR_4 PF12799.7 KFP12002.1 - 0.00098 19.5 36.0 0.35 11.4 0.2 8.7 6 2 6 12 12 12 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP12002.1 - 0.0021 17.8 38.5 0.018 14.8 0.9 8.3 4 3 4 8 8 8 4 Leucine rich repeat FISNA PF14484.6 KFP12002.1 - 0.0037 17.5 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 Fish-specific NACHT associated domain FAM25 PF15825.5 KFP12002.1 - 0.59 10.5 2.7 15 6.0 0.0 3.8 4 0 0 4 4 3 0 FAM25 family ABC_tran PF00005.27 KFP12002.1 - 0.89 10.1 8.2 1.8 9.1 0.0 4.3 5 0 0 5 5 5 0 ABC transporter LRR_12 PF18837.1 KFP12002.1 - 1.3 8.7 16.0 0.43 10.3 0.1 6.1 7 0 0 7 7 7 0 Leucine-rich repeat AAA_16 PF13191.6 KFP12002.1 - 4.4 7.7 6.8 2.1 8.7 0.0 3.3 2 2 1 4 4 4 0 AAA ATPase domain DnaJ_C PF01556.18 KFP12003.1 - 3e-26 92.3 0.2 4.2e-26 91.8 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP12003.1 - 3.8e-15 55.7 2.5 6.1e-15 55.1 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFP12003.1 - 2.8e-11 43.6 16.2 6.6e-11 42.4 16.2 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFP12003.1 - 0.061 13.3 14.1 0.2 11.6 4.0 3.2 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein RseC_MucC PF04246.12 KFP12003.1 - 2.6 8.0 4.4 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2318 PF10080.9 KFP12003.1 - 4.9 7.3 7.6 6.6 6.9 1.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 KFP12003.1 - 8.5 6.4 9.5 2.4 8.2 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WD40 PF00400.32 KFP12004.1 - 6.5e-12 45.8 0.9 1.6e-05 25.6 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP12004.1 - 9e-06 25.9 0.0 0.00018 21.7 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 KFP12004.1 - 0.0024 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Pam16 PF03656.13 KFP12005.1 - 7.2e-54 181.2 2.8 7.9e-54 181.1 2.8 1.0 1 0 0 1 1 1 1 Pam16 Integrase_Zn PF02022.19 KFP12005.1 - 0.19 11.7 3.2 5.7 7.0 0.3 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain CEP19 PF14933.6 KFP12006.1 - 0.017 15.4 2.2 0.017 15.4 2.2 1.6 2 0 0 2 2 2 0 CEP19-like protein APH PF01636.23 KFP12006.1 - 0.5 10.2 3.7 0.74 9.7 3.7 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SlyX PF04102.12 KFP12006.1 - 4.9 7.9 18.7 7.4 7.3 6.8 3.2 3 0 0 3 3 3 0 SlyX Dynamin_N PF00350.23 KFP12007.1 - 1.3e-10 41.6 0.0 6.6e-09 36.0 0.0 2.5 2 1 0 2 2 2 1 Dynamin family EHD_N PF16880.5 KFP12007.1 - 4.5e-10 39.2 0.0 9.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 KFP12007.1 - 7.5e-09 35.7 0.0 1.9e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP12007.1 - 0.001 19.0 0.0 0.22 11.4 0.0 3.4 4 0 0 4 4 4 1 RsgA GTPase Guanylate_cyc PF00211.20 KFP12008.1 - 8.9e-63 211.2 0.2 1.2e-62 210.7 0.2 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF512 PF04459.12 KFP12008.1 - 0.025 13.9 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF2207 PF09972.9 KFP12008.1 - 0.11 11.2 1.3 2.1 7.0 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) AC_N PF16214.5 KFP12008.1 - 0.35 10.0 0.0 0.35 10.0 0.0 3.1 4 0 0 4 4 4 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2157 PF09925.9 KFP12008.1 - 7.9 6.3 8.7 69 3.2 8.6 2.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Guanylate_cyc PF00211.20 KFP12009.1 - 2.5e-52 177.2 0.0 3.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAT_KAT11 PF08214.11 KFP12010.1 - 1.1e-68 232.2 0.5 1.1e-68 232.2 0.5 1.7 2 0 0 2 2 2 1 Histone acetylation protein KIX PF02172.16 KFP12010.1 - 3e-40 136.3 0.8 9.6e-40 134.7 0.8 1.9 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.16 KFP12010.1 - 1.9e-28 98.7 70.6 9.3e-19 67.7 20.6 3.6 3 0 0 3 3 3 2 TAZ zinc finger DUF902 PF06001.13 KFP12010.1 - 4.2e-22 78.3 9.2 4.2e-22 78.3 9.2 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Creb_binding PF09030.10 KFP12010.1 - 2.9e-21 76.2 14.1 2.9e-21 76.2 14.1 13.8 8 4 6 14 14 14 1 Creb binding Bromodomain PF00439.25 KFP12010.1 - 6.3e-17 61.4 0.0 1.6e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 KFP12010.1 - 1.6e-15 56.6 14.6 1.6e-15 56.6 14.6 3.3 3 0 0 3 3 3 1 Zinc finger, ZZ type KIX_2 PF16987.5 KFP12010.1 - 2e-05 24.5 0.2 9.6e-05 22.3 0.2 2.3 1 0 0 1 1 1 1 KIX domain HSP90 PF00183.18 KFP12011.1 - 2.9e-101 339.9 5.9 5.2e-96 322.6 2.0 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KFP12011.1 - 2.3e-11 43.7 0.0 8.2e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFP12011.1 - 3.7e-08 33.9 0.1 6.9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BDV_P10 PF06515.11 KFP12011.1 - 0.17 11.9 0.2 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Borna disease virus P10 protein Slx4 PF09494.10 KFP12012.1 - 5e-16 58.4 0.1 8e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 Slx4 endonuclease zf-H2C2_2 PF13465.6 KFP12013.1 - 2.5e-53 176.2 35.9 1.4e-10 41.1 0.7 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP12013.1 - 2.2e-37 125.4 41.2 9.7e-08 32.1 0.5 7.3 7 1 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP12013.1 - 1.1e-22 78.7 40.1 0.0011 19.6 0.7 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf_UBZ PF18439.1 KFP12013.1 - 2.3e-12 46.2 15.0 0.042 13.5 0.1 6.3 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KFP12013.1 - 3.1e-10 39.9 15.2 0.64 10.1 0.3 6.2 6 0 0 6 6 6 4 XPA protein N-terminal zf-C2H2_jaz PF12171.8 KFP12013.1 - 9.1e-10 38.6 4.4 0.061 13.6 0.1 5.7 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP12013.1 - 8.4e-09 35.2 44.0 0.0002 21.3 0.6 7.9 7 2 0 7 7 6 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP12013.1 - 2.1e-08 34.1 25.7 0.12 12.5 6.4 5.6 1 1 4 5 5 5 4 Zinc ribbon domain zf-LYAR PF08790.11 KFP12013.1 - 8e-08 32.1 16.6 0.31 11.0 0.1 6.3 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFP12013.1 - 8.2e-08 31.9 35.7 0.14 11.9 0.1 7.0 7 0 0 7 7 7 4 zinc-finger C2H2-type zf-trcl PF13451.6 KFP12013.1 - 1.1e-07 31.6 15.1 1.6 8.7 0.2 6.1 6 0 0 6 6 6 1 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 KFP12013.1 - 1.9e-06 27.7 10.1 1.3 9.0 0.7 5.8 4 1 1 5 5 5 2 zinc-ribbon domain FYDLN_acid PF09538.10 KFP12013.1 - 2.4e-06 28.1 5.9 9.2 7.0 0.0 5.8 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.13 KFP12013.1 - 2.6e-06 27.0 17.9 2.7 7.7 0.1 6.2 6 0 0 6 6 6 1 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.6 KFP12013.1 - 2.5e-05 24.3 12.3 8.7 6.4 0.1 5.9 2 2 4 6 6 6 0 CpXC protein zinc_ribbon_15 PF17032.5 KFP12013.1 - 2.6e-05 24.9 10.8 0.18 12.6 2.0 3.1 2 1 1 3 3 3 2 zinc-ribbon family YhfH PF14149.6 KFP12013.1 - 4.5e-05 23.3 19.6 2.4 8.2 0.2 6.1 6 0 0 6 6 6 1 YhfH-like protein TFIIS_C PF01096.18 KFP12013.1 - 6.7e-05 22.7 19.8 7.7 6.5 0.1 6.1 5 1 0 5 5 5 0 Transcription factor S-II (TFIIS) DZR PF12773.7 KFP12013.1 - 0.00019 21.4 18.7 1.9e+03 -1.0 18.7 3.6 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.12 KFP12013.1 - 0.00033 20.8 18.3 0.062 13.5 2.8 4.2 1 1 2 4 4 4 2 TFIIH C1-like domain ADK_lid PF05191.14 KFP12013.1 - 0.00099 19.0 7.3 4.4 7.4 0.4 5.1 1 1 4 5 5 5 0 Adenylate kinase, active site lid Zn_ribbon_recom PF13408.6 KFP12013.1 - 0.003 18.1 15.8 15 6.2 0.1 5.9 1 1 6 7 7 7 0 Recombinase zinc beta ribbon domain DUF3268 PF11672.8 KFP12013.1 - 0.0036 17.6 12.0 0.34 11.3 0.2 3.8 2 2 3 5 5 5 2 zinc-finger-containing domain zf_C2H2_ZHX PF18387.1 KFP12013.1 - 0.0039 16.8 27.0 0.17 11.6 0.3 6.2 1 1 5 6 6 6 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-AN1 PF01428.16 KFP12013.1 - 0.0043 17.2 22.1 8 6.7 0.7 6.3 5 1 1 6 6 6 0 AN1-like Zinc finger zf-UBR PF02207.20 KFP12013.1 - 0.0056 16.8 18.4 1.1e+03 -0.1 18.4 4.0 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) LIM PF00412.22 KFP12013.1 - 0.0059 16.8 18.5 1.4 9.2 2.6 4.8 1 1 4 5 5 5 3 LIM domain DUF2256 PF10013.9 KFP12013.1 - 0.0069 16.5 13.6 1.7 8.8 0.3 5.8 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 KFP12013.1 - 0.014 16.1 14.6 8.1 7.1 0.6 4.7 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FAM178 PF14816.6 KFP12013.1 - 0.03 13.3 0.3 27 3.6 0.1 3.4 1 1 1 4 4 4 0 Family of unknown function, FAM178 zf-C2HE PF16278.5 KFP12013.1 - 0.041 14.3 21.7 5.1 7.6 0.8 5.9 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zinc-ribbons_6 PF07191.12 KFP12013.1 - 0.053 13.5 15.0 45 4.1 5.8 4.6 1 1 1 2 2 2 0 zinc-ribbons Elf1 PF05129.13 KFP12013.1 - 0.11 12.5 13.2 0.83 9.7 1.2 4.0 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like DUF4303 PF14136.6 KFP12013.1 - 0.16 11.7 0.0 27 4.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4303) zf-Mss51 PF13824.6 KFP12013.1 - 0.18 11.9 29.9 0.92 9.7 0.9 6.0 1 1 4 5 5 5 0 Zinc-finger of mitochondrial splicing suppressor 51 Pombe_5TM PF09437.10 KFP12013.1 - 0.21 11.2 0.3 22 4.6 0.0 2.6 1 1 1 2 2 2 0 Pombe specific 5TM protein HNH PF01844.23 KFP12013.1 - 0.41 10.9 22.2 3.5 7.9 0.1 6.0 6 0 0 6 6 6 0 HNH endonuclease Zn_ribbon_SprT PF17283.2 KFP12013.1 - 0.53 10.2 20.3 5.7 6.9 1.4 5.2 4 2 0 4 4 4 0 SprT-like zinc ribbon domain DUF2072 PF09845.9 KFP12013.1 - 0.62 10.3 16.1 35 4.7 0.1 5.5 5 1 1 6 6 6 0 Zn-ribbon containing protein Yippee-Mis18 PF03226.14 KFP12013.1 - 0.83 9.9 11.8 1.3 9.2 2.0 3.9 2 1 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1595 PF12760.7 KFP12013.1 - 0.91 9.6 30.2 7.3 6.7 5.1 4.9 1 1 5 6 6 6 0 Transposase zinc-ribbon domain zf-Paramyx-P PF13008.7 KFP12013.1 - 1.3 8.5 17.1 16 5.1 0.1 5.7 6 0 0 6 6 6 0 Zinc-binding domain of Paramyxoviridae V protein zinc_ribbon_9 PF14369.6 KFP12013.1 - 1.9 8.8 18.9 8.6 6.7 0.1 5.7 5 1 1 6 6 6 0 zinc-ribbon Ribosomal_L44 PF00935.19 KFP12013.1 - 2.6 8.6 14.9 45 4.6 0.1 5.3 5 1 1 6 6 5 0 Ribosomal protein L44 FYVE PF01363.21 KFP12013.1 - 4.8 7.4 25.8 4.3 7.6 3.0 4.8 1 1 3 4 4 3 0 FYVE zinc finger zf-DNL PF05180.12 KFP12013.1 - 5.6 7.0 11.9 1.5 8.8 0.3 3.3 3 0 0 3 3 3 0 DNL zinc finger zf-met PF12874.7 KFP12013.1 - 5.9 7.4 22.8 6.3 7.3 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Rubredoxin_2 PF18073.1 KFP12013.1 - 7 6.5 31.1 4.8 7.0 0.5 6.1 6 0 0 6 6 6 0 Rubredoxin metal binding domain Heme_oxygenase PF01126.20 KFP12014.1 - 6.7e-83 277.5 5.3 7.8e-83 277.3 5.3 1.0 1 0 0 1 1 1 1 Heme oxygenase zf-LITAF-like PF10601.9 KFP12015.1 - 8.4e-24 83.6 16.9 1.4e-23 82.9 16.9 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain COMP PF11598.8 KFP12016.1 - 0.028 14.9 3.0 1 9.9 0.9 2.3 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Sec8_exocyst PF04048.14 KFP12016.1 - 0.08 12.8 1.7 0.088 12.7 1.7 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF4507 PF14964.6 KFP12017.1 - 5.6e-112 374.2 1.9 6.6e-112 374.0 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Exo_endo_phos PF03372.23 KFP12018.1 - 9.8e-12 44.9 0.1 1.1e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 KFP12019.1 - 2.5e-09 37.0 0.1 3.2e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ECH_1 PF00378.20 KFP12020.1 - 5.8e-77 258.4 0.0 7.3e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP12020.1 - 2.1e-11 43.9 0.0 2.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase YwhD PF08741.10 KFP12020.1 - 0.034 13.8 0.3 0.057 13.1 0.3 1.3 1 0 0 1 1 1 0 YwhD family Voltage_CLC PF00654.20 KFP12021.1 - 8.7e-97 324.5 27.2 3.6e-96 322.5 24.8 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFP12021.1 - 3.7e-14 52.9 0.1 2.4e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF1077 PF06417.12 KFP12022.1 - 1.1e-23 83.5 0.5 1.2e-23 83.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Tropomodulin PF03250.14 KFP12023.1 - 2.3e-06 27.7 16.8 2.3e-06 27.7 16.8 3.8 2 1 1 3 3 3 1 Tropomodulin WH2 PF02205.20 KFP12023.1 - 0.0004 20.1 1.1 0.0013 18.5 1.1 2.0 1 0 0 1 1 1 1 WH2 motif LRR_6 PF13516.6 KFP12023.1 - 0.013 15.5 1.7 0.045 13.8 0.2 2.5 2 0 0 2 2 2 0 Leucine Rich repeat Tim17 PF02466.19 KFP12024.1 - 1.7e-31 108.9 5.1 2e-31 108.6 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HlyIII PF03006.20 KFP12025.1 - 2.4e-73 246.6 19.6 2.9e-73 246.3 19.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4405 PF14358.6 KFP12025.1 - 0.011 16.3 3.3 0.011 16.3 3.3 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) DUF962 PF06127.11 KFP12025.1 - 1.4 9.1 9.1 0.051 13.7 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) UQ_con PF00179.26 KFP12026.1 - 2.6e-39 134.1 0.0 2.9e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP12026.1 - 0.0055 17.0 0.2 0.0063 16.8 0.2 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP12026.1 - 0.0073 16.0 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP12026.1 - 0.0086 15.9 0.1 0.018 14.9 0.1 1.6 1 1 0 1 1 1 1 UEV domain LRIF1 PF15741.5 KFP12027.1 - 6.3e-176 587.1 34.2 2e-174 582.2 34.2 2.7 1 1 0 1 1 1 1 Ligand-dependent nuclear receptor-interacting factor 1 Thioredoxin_9 PF14595.6 KFP12027.1 - 0.065 13.0 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Frag1 PF10277.9 KFP12028.1 - 1.9e-46 158.3 17.9 2.3e-46 158.1 17.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TMEM70 PF06979.12 KFP12028.1 - 0.043 14.2 4.4 0.077 13.4 1.0 2.4 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex TssN PF17555.2 KFP12028.1 - 0.37 10.1 11.8 0.33 10.3 10.8 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF3989 PF13150.6 KFP12028.1 - 4.5 7.1 6.2 14 5.5 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) CDP-OH_P_transf PF01066.21 KFP12029.1 - 1.2e-18 67.6 0.1 1.2e-18 67.6 0.1 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DENN PF02141.21 KFP12030.1 - 3.4e-57 193.4 2.1 6.5e-57 192.5 2.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP12030.1 - 1.9e-15 57.3 0.0 3.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP12030.1 - 7.9e-10 38.6 2.3 1.6e-09 37.6 2.3 1.5 1 0 0 1 1 1 1 dDENN domain 7tm_6 PF02949.20 KFP12030.1 - 0.05 12.7 0.3 0.13 11.3 0.1 1.7 1 1 0 1 1 1 0 7tm Odorant receptor SPA PF08616.10 KFP12030.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis SAM_1 PF00536.30 KFP12031.1 - 6.3e-27 93.8 1.4 3.7e-13 49.7 0.2 3.9 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP12031.1 - 2.2e-25 88.5 1.1 6.4e-11 42.2 0.1 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) CREPT PF16566.5 KFP12031.1 - 0.0037 17.4 10.3 0.0037 17.4 10.3 5.6 3 2 2 5 5 5 1 Cell-cycle alteration and expression-elevated protein in tumour DUF2576 PF10845.8 KFP12031.1 - 0.091 12.4 0.2 0.36 10.5 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) F-box-like PF12937.7 KFP12032.1 - 0.044 13.7 2.6 0.092 12.7 2.6 1.5 1 0 0 1 1 1 0 F-box-like Tmemb_9 PF05434.11 KFP12033.1 - 1.8e-53 180.4 0.1 2.7e-53 179.8 0.1 1.3 1 0 0 1 1 1 1 TMEM9 Metal_resist PF13801.6 KFP12033.1 - 0.022 15.0 1.2 0.036 14.3 1.2 1.2 1 0 0 1 1 1 0 Heavy-metal resistance fn3 PF00041.21 KFP12034.1 - 1.7e-59 198.1 9.8 9.6e-16 57.9 0.0 4.7 4 0 0 4 4 4 4 Fibronectin type III domain I-set PF07679.16 KFP12034.1 - 2.2e-56 187.9 0.5 7e-19 67.7 0.0 6.0 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12034.1 - 1.8e-36 124.6 6.6 1.7e-14 54.1 0.0 6.6 8 1 0 8 8 8 4 Immunoglobulin domain Ig_2 PF13895.6 KFP12034.1 - 5.3e-18 65.1 0.0 2.2e-08 34.3 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFP12034.1 - 1.7e-16 60.1 4.4 0.00076 19.6 0.0 5.7 7 0 0 7 7 6 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP12034.1 - 5.7e-13 49.2 6.6 0.034 14.7 1.0 5.8 4 1 1 5 5 5 3 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFP12034.1 - 3.5e-11 42.9 0.3 0.017 15.0 0.0 4.4 4 0 0 4 4 4 3 Tissue factor V-set PF07686.17 KFP12034.1 - 5.1e-09 36.3 1.6 0.38 10.9 0.0 6.5 5 3 1 6 6 5 2 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 KFP12034.1 - 1.1e-08 35.3 0.0 0.069 13.4 0.0 4.1 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 KFP12034.1 - 1.5e-06 28.2 0.1 0.0091 16.0 0.0 3.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain DUF2369 PF10179.9 KFP12034.1 - 3.2e-05 24.2 0.2 10 6.6 0.1 4.7 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 KFP12034.1 - 0.00014 22.4 0.0 0.1 13.1 0.0 3.9 4 0 0 4 4 4 1 PhoD-like phosphatase, N-terminal domain SusE PF14292.6 KFP12034.1 - 0.00078 19.6 3.9 0.12 12.6 0.1 3.8 3 2 1 4 4 4 1 SusE outer membrane protein DUF4945 PF16303.5 KFP12034.1 - 0.046 13.7 0.1 2 8.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) PH_RBD PF12068.8 KFP12034.1 - 0.067 12.7 0.2 0.61 9.5 0.0 2.3 2 0 0 2 2 2 0 Rab-binding domain (RBD) Lectin_like PF18560.1 KFP12034.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Lectin like domain Top6b_C PF18000.1 KFP12034.1 - 0.1 12.8 0.3 7.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Arm PF00514.23 KFP12035.1 - 7.1e-28 95.8 5.5 2.2e-09 37.0 0.0 7.6 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP12035.1 - 1.5e-06 28.6 3.1 0.06 13.9 0.1 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 KFP12035.1 - 0.0027 18.1 0.4 0.18 12.2 0.1 3.0 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 KFP12035.1 - 0.004 17.3 1.7 1.9 8.9 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat V-ATPase_H_C PF11698.8 KFP12035.1 - 0.0081 16.3 0.0 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Adaptin_N PF01602.20 KFP12035.1 - 0.021 13.4 0.4 5.7 5.4 0.0 2.5 1 1 0 2 2 2 0 Adaptin N terminal region Mo25 PF08569.11 KFP12035.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 Mo25-like Troponin PF00992.20 KFP12036.1 - 2.4e-37 128.2 47.0 1.1e-33 116.4 36.9 2.0 1 1 1 2 2 2 2 Troponin DUF4250 PF14056.6 KFP12036.1 - 0.025 14.5 0.8 0.063 13.2 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) UCR_TM PF02921.14 KFP12036.1 - 2.7 8.6 3.8 1.8 9.1 0.1 2.6 1 1 1 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Troponin PF00992.20 KFP12037.1 - 2.6e-49 167.0 7.3 3.6e-49 166.5 7.3 1.2 1 0 0 1 1 1 1 Troponin Tup_N PF08581.10 KFP12037.1 - 0.021 15.1 2.6 0.032 14.5 0.1 2.3 2 0 0 2 2 2 0 Tup N-terminal XkdW PF09636.10 KFP12037.1 - 0.084 13.0 2.2 0.47 10.6 2.2 2.2 1 1 0 1 1 1 0 XkdW protein DUF2951 PF11166.8 KFP12037.1 - 0.37 11.0 5.0 1 9.6 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) Med9 PF07544.13 KFP12037.1 - 1 9.5 6.9 15 5.7 0.1 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PH_15 PF17339.2 KFP12038.1 - 2.8e-06 27.2 0.1 4.6e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 PH domain PH PF00169.29 KFP12038.1 - 9.3e-06 26.1 0.1 1.1e-05 25.8 0.1 1.1 1 0 0 1 1 1 1 PH domain LIM PF00412.22 KFP12039.1 - 1.6e-29 101.9 21.6 1.2e-16 60.7 2.4 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KFP12039.1 - 0.064 12.9 10.2 1.1 8.9 0.3 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KFP12039.1 - 0.41 10.8 0.2 0.41 10.8 0.2 4.6 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain Dynactin_p62 PF05502.13 KFP12039.1 - 1.2 7.8 8.7 3.7 6.2 0.4 2.1 2 0 0 2 2 2 0 Dynactin p62 family zf-C3HC4_3 PF13920.6 KFP12039.1 - 3.9 7.4 15.5 0.74 9.7 2.8 3.9 3 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_12 PF18658.1 KFP12039.1 - 7.4 6.2 9.1 3.8 7.2 1.7 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type PRKG1_interact PF15898.5 KFP12040.1 - 4.3e-35 120.7 21.4 4.3e-35 120.7 21.4 5.9 7 2 0 7 7 7 1 cGMP-dependent protein kinase interacting domain Ank_4 PF13637.6 KFP12040.1 - 2.2e-27 95.1 0.8 1.2e-12 48.1 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP12040.1 - 2.4e-25 88.9 0.4 1.3e-12 48.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP12040.1 - 6e-24 83.8 1.7 2e-09 37.5 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP12040.1 - 1.1e-20 73.1 4.3 3.8e-06 27.1 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KFP12040.1 - 1.2e-17 62.2 1.5 0.00059 20.1 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat C2 PF00168.30 KFP12041.1 - 2.6e-55 185.1 0.2 1.5e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 KFP12041.1 - 2.7e-05 23.8 0.0 0.096 12.2 0.0 2.4 1 1 1 2 2 2 2 CEP76 C2 domain MAP17 PF15807.5 KFP12041.1 - 0.0001 22.5 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM52 PF14979.6 KFP12041.1 - 0.0005 20.0 1.5 0.00093 19.1 1.5 1.4 1 0 0 1 1 1 1 Transmembrane 52 DOCK-C2 PF14429.6 KFP12041.1 - 0.00071 19.4 0.0 0.78 9.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 KFP12041.1 - 0.0008 19.3 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 FAM176 PF14851.6 KFP12041.1 - 0.0095 15.6 0.4 0.018 14.7 0.4 1.4 1 0 0 1 1 1 1 FAM176 family EphA2_TM PF14575.6 KFP12041.1 - 0.011 16.7 0.0 0.024 15.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 KFP12041.1 - 0.021 15.2 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Commissureless Transglut_C PF00927.22 KFP12041.1 - 0.04 14.1 0.8 6.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Peptidase_M1 PF01433.20 KFP12042.1 - 7.8e-49 166.2 0.0 1.6e-48 165.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFP12042.1 - 5.7e-32 110.2 0.3 9.3e-32 109.5 0.3 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFP12042.1 - 2.3e-14 54.0 1.9 4.2e-14 53.2 1.9 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KFP12042.1 - 0.039 13.6 0.2 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Sec7 PF01369.20 KFP12042.1 - 0.04 13.6 0.1 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Sec7 domain Kelch_3 PF13415.6 KFP12043.1 - 1.1e-41 140.4 1.5 9.8e-06 25.7 0.1 8.1 8 0 0 8 8 8 7 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP12043.1 - 4.1e-35 119.5 6.6 1.3e-08 34.7 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFP12043.1 - 1.7e-33 115.2 6.4 5.7e-21 74.8 0.0 4.8 2 2 2 4 4 4 3 BTB/POZ domain Kelch_1 PF01344.25 KFP12043.1 - 6.1e-32 109.0 5.2 1.9e-08 33.7 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP12043.1 - 8.3e-31 105.5 4.6 4.6e-07 29.7 0.3 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP12043.1 - 2.1e-26 91.3 9.4 4.3e-09 36.3 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFP12043.1 - 2.6e-19 68.4 2.0 1.8e-06 27.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif RAG2 PF03089.14 KFP12043.1 - 0.001 18.1 0.0 0.0082 15.2 0.0 2.2 2 0 0 2 2 2 1 Recombination activating protein 2 BACK PF07707.15 KFP12043.1 - 0.0015 18.6 12.4 0.0059 16.7 1.1 4.7 4 1 1 5 5 5 1 BTB And C-terminal Kelch PLU-1 PF08429.11 KFP12044.1 - 4.8e-95 318.6 11.7 4e-91 305.7 5.1 3.9 4 0 0 4 4 4 3 PLU-1-like protein JmjC PF02373.22 KFP12044.1 - 6.8e-45 152.2 0.7 1.5e-44 151.0 0.7 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KFP12044.1 - 6.4e-25 86.8 38.1 1.1e-11 44.5 4.1 4.2 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KFP12044.1 - 1.1e-17 64.5 0.0 2.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KFP12044.1 - 1.9e-13 50.6 12.1 1.9e-13 50.6 12.1 3.6 3 0 0 3 3 3 1 C5HC2 zinc finger PHD_2 PF13831.6 KFP12044.1 - 0.07 12.7 27.8 0.3 10.7 2.6 4.0 4 0 0 4 4 4 0 PHD-finger Lipoprotein_20 PF13942.6 KFP12044.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.3 3 0 0 3 3 3 0 YfhG lipoprotein FYVE_2 PF02318.16 KFP12044.1 - 3.4 7.9 24.3 2.4 8.4 1.0 4.9 4 0 0 4 4 4 0 FYVE-type zinc finger Zf_RING PF16744.5 KFP12044.1 - 3.8 7.7 11.4 1.4 9.1 1.0 3.5 3 0 0 3 3 3 0 KIAA1045 RING finger Tubulin PF00091.25 KFP12045.1 - 4.4e-68 229.4 0.0 5.9e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP12045.1 - 5.8e-49 165.4 0.0 8.9e-49 164.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP12045.1 - 0.0055 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain NUDIX_5 PF16705.5 KFP12045.1 - 0.08 12.7 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Kelch_1 PF01344.25 KFP12046.1 - 2.9e-80 263.6 18.5 1.1e-14 53.7 0.2 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFP12046.1 - 6e-45 150.1 13.3 4.2e-10 39.5 0.0 6.2 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFP12046.1 - 1.2e-34 118.4 0.8 2.5e-34 117.5 0.8 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP12046.1 - 5.9e-30 102.1 4.3 7e-05 22.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP12046.1 - 1.5e-27 95.2 11.4 1.4e-07 31.6 0.7 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP12046.1 - 8.9e-25 86.5 9.8 0.0004 20.3 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP12046.1 - 2.7e-13 49.6 10.0 0.02 14.9 0.1 6.1 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 KFP12046.1 - 3.7e-11 43.2 0.5 6.9e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Glu_cyclase_2 PF05096.12 KFP12046.1 - 0.11 12.0 0.0 0.41 10.0 0.0 1.9 1 1 0 1 1 1 0 Glutamine cyclotransferase LRR_8 PF13855.6 KFP12047.1 - 4.1e-68 225.0 39.7 2.8e-16 59.0 0.3 7.2 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP12047.1 - 1.8e-35 120.3 22.4 6.7e-06 26.4 0.1 8.8 5 1 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP12047.1 - 4e-19 68.8 0.0 1.1e-07 31.9 0.0 3.4 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP12047.1 - 1.1e-13 51.1 8.5 0.00014 21.4 0.1 4.4 1 1 4 5 5 5 5 Leucine-rich repeat 7tm_1 PF00001.21 KFP12047.1 - 1.3e-07 31.3 14.6 2.9e-07 30.1 14.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_1 PF00560.33 KFP12047.1 - 1.6e-07 30.9 25.6 5.6 7.9 0.0 10.3 10 2 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 KFP12047.1 - 0.042 13.9 31.1 0.31 11.2 0.0 8.4 10 0 0 10 10 10 0 Leucine Rich repeat Arf PF00025.21 KFP12048.1 - 8e-30 103.6 0.2 1.7e-29 102.5 0.2 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP12048.1 - 6e-07 29.2 0.0 4.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFP12048.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase 7tm_1 PF00001.21 KFP12049.1 - 8.2e-23 81.1 16.5 1.2e-22 80.5 16.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.12 KFP12049.1 - 0.017 15.0 3.1 0.3 11.0 0.1 2.7 2 0 0 2 2 2 0 CDR ABC transporter COX7C PF02935.16 KFP12049.1 - 0.11 12.8 1.1 18 5.7 0.0 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Ets PF00178.22 KFP12050.1 - 8.5e-31 106.3 1.3 1.5e-30 105.4 1.3 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP12050.1 - 1.3e-17 63.5 0.0 4.9e-17 61.7 0.0 2.0 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain AT_hook PF02178.19 KFP12050.1 - 0.15 12.0 5.1 0.36 10.8 5.1 1.7 1 0 0 1 1 1 0 AT hook motif CH PF00307.31 KFP12050.1 - 0.19 11.9 0.2 0.51 10.5 0.1 1.7 2 0 0 2 2 2 0 Calponin homology (CH) domain Kinesin PF00225.23 KFP12051.1 - 1.3e-102 343.2 0.0 1.3e-102 343.2 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain WD40 PF00400.32 KFP12051.1 - 3.2e-28 97.4 8.2 0.00055 20.7 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Microtub_bd PF16796.5 KFP12051.1 - 3.6e-19 69.2 1.2 6.2e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Nup160 PF11715.8 KFP12051.1 - 0.00021 20.1 1.6 6.4 5.3 0.0 5.1 3 1 2 5 5 5 1 Nucleoporin Nup120/160 TPR_MLP1_2 PF07926.12 KFP12051.1 - 0.011 15.8 1.9 0.011 15.8 1.9 6.4 5 2 1 6 6 6 0 TPR/MLP1/MLP2-like protein ANAPC4_WD40 PF12894.7 KFP12051.1 - 0.022 15.1 0.0 18 5.7 0.0 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4094 PF13334.6 KFP12051.1 - 0.092 13.2 0.1 0.092 13.2 0.1 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4094) AAA_25 PF13481.6 KFP12051.1 - 4.8 6.7 6.7 2.9 7.4 0.1 3.2 3 0 0 3 3 3 0 AAA domain OTU PF02338.19 KFP12052.1 - 3.7e-11 43.6 0.0 1.2e-10 41.9 0.0 2.0 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 KFP12052.1 - 0.03 14.1 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Mut7-C PF01927.16 KFP12052.1 - 0.095 12.8 0.1 3.3 7.8 0.1 2.6 2 0 0 2 2 2 0 Mut7-C RNAse domain P120R PF08062.11 KFP12052.1 - 4.7 7.7 7.4 0.45 10.9 1.6 2.4 2 0 0 2 2 2 0 P120R (NUC006) repeat Cmyb_C PF09316.10 KFP12053.1 - 1.1e-79 265.9 2.5 2.4e-79 264.7 2.5 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFP12053.1 - 5.6e-52 173.7 17.5 4e-18 65.3 2.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP12053.1 - 1.6e-39 133.9 17.7 6.8e-18 64.7 2.2 4.2 2 1 2 4 4 4 3 Myb-like DNA-binding domain LMSTEN PF07988.12 KFP12053.1 - 5.7e-26 89.7 0.5 1.2e-25 88.7 0.5 1.6 1 0 0 1 1 1 1 LMSTEN motif Myb_DNA-bind_7 PF15963.5 KFP12053.1 - 6.7e-08 32.3 5.3 0.00035 20.4 0.1 3.8 1 1 2 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KFP12053.1 - 2.2e-06 27.6 6.3 0.75 9.8 0.2 4.5 2 1 2 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 KFP12053.1 - 0.021 15.0 7.0 1.2 9.3 0.0 3.8 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KFP12053.1 - 0.19 11.8 9.7 30 4.8 5.9 4.2 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 KFP12053.1 - 0.64 10.1 3.1 1.2 9.2 0.1 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Fe-ADH PF00465.19 KFP12055.1 - 1.3e-99 333.5 0.0 1.5e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFP12055.1 - 3.4e-15 56.4 0.0 2.5e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DnaJ PF00226.31 KFP12056.1 - 3.7e-26 91.0 2.7 6.3e-26 90.3 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 KFP12056.1 - 0.065 11.7 2.0 0.084 11.3 2.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CCER1 PF15482.6 KFP12056.1 - 1.1 9.1 6.8 1.5 8.7 6.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Mito_fiss_reg PF05308.11 KFP12057.1 - 3.4e-81 273.0 3.9 4.9e-81 272.5 3.9 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator VIR_N PF15912.5 KFP12057.1 - 0.95 9.0 6.2 1.9 8.0 6.2 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 KFP12057.1 - 1.4 9.0 10.4 3.4 7.7 10.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Arm PF00514.23 KFP12058.1 - 3.7e-05 23.6 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.26 KFP12058.1 - 0.0017 18.7 0.1 0.0032 17.9 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain p450 PF00067.22 KFP12061.1 - 9.3e-49 166.4 0.2 1.3e-48 165.9 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4462 PF14692.6 KFP12064.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) YTH PF04146.15 KFP12065.1 - 1.2e-39 135.9 0.5 1.2e-39 135.9 0.5 2.3 2 1 0 2 2 2 1 YT521-B-like domain TFIIA PF03153.13 KFP12065.1 - 0.021 14.9 10.9 0.033 14.2 10.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRAL_TRIO PF00650.20 KFP12066.1 - 2.3e-32 111.9 0.0 2.9e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain DUF5007 PF16398.5 KFP12066.1 - 0.18 11.4 0.0 0.36 10.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5007) Peptidase_C26 PF07722.13 KFP12067.1 - 5.4e-22 78.6 0.0 2.4e-21 76.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 KFP12067.1 - 5.5e-09 36.1 0.0 8.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_M1 PF01433.20 KFP12069.1 - 1.5e-81 273.1 0.7 4.1e-81 271.7 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFP12069.1 - 8.1e-71 239.1 1.0 1.2e-70 238.5 1.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFP12069.1 - 8.2e-34 117.4 0.1 2e-33 116.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF1570 PF07607.11 KFP12069.1 - 0.094 13.0 0.3 0.42 10.9 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) Calpain_inhib PF00748.19 KFP12070.1 - 2.3e-121 400.6 104.9 3.2e-36 124.8 8.6 6.8 5 1 2 7 7 7 5 Calpain inhibitor Peptidase_S8 PF00082.22 KFP12071.1 - 1.3e-46 159.2 1.9 2e-46 158.7 1.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP12071.1 - 3.8e-30 103.8 0.4 7.5e-30 102.8 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Proho_convert PF12177.8 KFP12071.1 - 8.4e-22 76.9 4.4 9e-22 76.8 2.5 2.1 2 0 0 2 2 2 1 Prohormone convertase enzyme S8_pro-domain PF16470.5 KFP12071.1 - 2.7e-13 50.5 3.5 7.1e-13 49.1 3.5 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFP12071.1 - 0.0034 17.9 0.9 0.01 16.4 0.9 1.8 1 0 0 1 1 1 1 N-terminal of Subtilase family TPD PF14811.6 KFP12072.1 - 2.9e-55 185.9 0.3 5.7e-55 184.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif Sec34 PF04136.15 KFP12072.1 - 0.015 15.2 0.4 0.023 14.6 0.4 1.3 1 0 0 1 1 1 0 Sec34-like family PRP9_N PF16958.5 KFP12072.1 - 0.14 12.2 2.7 0.24 11.4 2.7 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus CtsR PF05848.11 KFP12072.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 CtsR N-terminal HTH domain Meis_PKNOX_N PF16493.5 KFP12073.1 - 4.8e-27 94.1 0.8 7.4e-27 93.5 0.8 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFP12073.1 - 9e-21 73.5 1.0 1.6e-20 72.7 1.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP12073.1 - 1.7e-08 34.2 0.4 3.1e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 Homeodomain DUF2465 PF10239.9 KFP12075.1 - 6.7e-131 436.3 0.3 7.7e-131 436.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DotA PF11388.8 KFP12075.1 - 0.0095 16.1 0.1 0.066 13.4 0.0 2.1 2 0 0 2 2 2 1 Phagosome trafficking protein DotA Baculo_p24 PF05073.12 KFP12075.1 - 0.094 12.5 0.3 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein RasGEF PF00617.19 KFP12076.1 - 2.1e-44 151.8 1.4 2.6e-44 151.5 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain C1_1 PF00130.22 KFP12076.1 - 3.3e-15 55.7 7.9 7.1e-15 54.6 7.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.20 KFP12076.1 - 5.1e-08 33.1 3.5 5.5e-08 33.0 1.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_7 PF13499.6 KFP12076.1 - 9.9e-07 29.1 3.5 0.00093 19.6 0.4 3.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP12076.1 - 6.6e-06 25.3 0.4 3.9e-05 22.9 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP12076.1 - 9.7e-06 25.1 0.1 5.4e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFP12076.1 - 7.3e-05 22.1 0.1 0.00032 20.0 0.1 2.2 2 0 0 2 2 2 1 EF hand ACDC PF14733.6 KFP12076.1 - 0.00081 19.7 1.9 0.0018 18.5 0.5 2.3 2 0 0 2 2 2 1 AP2-coincident C-terminal EF-hand_8 PF13833.6 KFP12076.1 - 0.013 15.4 0.1 0.051 13.4 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair UvrD_C PF13361.6 KFP12076.1 - 0.043 13.2 0.6 0.075 12.4 0.6 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain bZIP_1 PF00170.21 KFP12076.1 - 0.063 13.4 2.1 0.24 11.5 2.1 2.1 1 0 0 1 1 1 0 bZIP transcription factor RhoGAP PF00620.27 KFP12077.1 - 1.1e-31 109.7 0.3 2.6e-31 108.5 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain Secretogranin_V PF05281.11 KFP12078.1 - 1.1e-05 25.2 0.5 0.012 15.3 0.1 2.1 1 1 1 2 2 2 2 Neuroendocrine protein 7B2 precursor (Secretogranin V) DAN PF03045.15 KFP12080.1 - 8.5e-37 125.7 5.6 1.3e-36 125.1 5.6 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP12080.1 - 0.0034 17.6 4.7 0.0047 17.2 4.7 1.2 1 0 0 1 1 1 1 Cystine-knot domain zf-C2HCIx2C PF10782.9 KFP12080.1 - 1.5 8.8 8.4 2.7 8.0 2.3 2.3 1 1 1 2 2 2 0 Zinc-finger FH2 PF02181.23 KFP12081.1 - 4.2e-98 328.9 6.1 4.2e-98 328.9 6.1 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain DUF2012 PF09430.10 KFP12086.1 - 5.3e-30 104.1 0.1 7e-30 103.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Katanin_con80 PF13925.6 KFP12087.1 - 4.7e-35 121.0 0.1 7.9e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 con80 domain of Katanin TSP_C PF05735.12 KFP12089.1 - 3.7e-69 232.6 0.7 5.3e-69 232.1 0.7 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFP12089.1 - 1.4e-57 191.0 156.8 2.6e-12 46.2 13.6 10.4 9 2 2 11 11 11 9 Thrombospondin type 3 repeat TSP_1 PF00090.19 KFP12089.1 - 1.3e-40 137.3 46.5 1e-16 60.8 8.0 5.1 6 0 0 6 6 6 3 Thrombospondin type 1 domain VWC PF00093.18 KFP12089.1 - 1.3e-12 47.9 17.8 1.3e-12 47.9 17.8 6.6 4 3 1 5 5 5 1 von Willebrand factor type C domain EGF_3 PF12947.7 KFP12089.1 - 1.4e-06 28.4 10.5 1.4e-06 28.4 10.5 6.1 5 0 0 5 5 5 2 EGF domain cEGF PF12662.7 KFP12089.1 - 2e-06 27.6 1.2 2e-06 27.6 1.2 5.0 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP12089.1 - 1.4e-05 25.2 1.6 1.4e-05 25.2 1.6 5.9 5 0 0 5 5 5 3 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFP12089.1 - 0.00011 22.4 0.6 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP12089.1 - 0.0013 19.0 11.8 0.0013 19.0 11.8 7.0 6 1 1 7 7 7 2 EGF-like domain Laminin_G_2 PF02210.24 KFP12089.1 - 0.0039 17.8 0.2 0.0086 16.6 0.2 1.5 1 0 0 1 1 1 1 Laminin G domain FSIP1 PF15554.6 KFP12091.1 - 5.2e-31 108.1 6.6 7.3e-31 107.7 6.6 1.2 1 0 0 1 1 1 1 FSIP1 family SGT1 PF07093.11 KFP12091.1 - 0.18 10.2 3.2 0.2 10.1 3.2 1.1 1 0 0 1 1 1 0 SGT1 protein 7tm_1 PF00001.21 KFP12092.1 - 1.2e-30 106.7 28.4 1.5e-30 106.4 28.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 KFP12093.1 - 4.1e-79 265.7 11.7 3.3e-36 125.0 0.0 4.8 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12093.1 - 1e-44 152.8 10.2 2.6e-19 69.5 0.3 5.3 4 2 0 4 4 4 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 KFP12093.1 - 5.7e-17 62.1 0.5 5.7e-17 62.1 0.5 2.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 KFP12093.1 - 8.9e-15 54.7 0.2 1.8e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KFP12093.1 - 2.9e-14 53.3 1.0 9.7e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 RWD domain Kinase-like PF14531.6 KFP12093.1 - 1.7e-05 24.3 0.0 0.11 11.8 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KFP12093.1 - 0.00057 19.3 0.4 0.43 9.9 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP12093.1 - 0.042 13.8 0.1 0.042 13.8 0.1 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Goodbye PF17109.5 KFP12093.1 - 1.7 9.1 6.8 29 5.1 6.4 2.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain SRP14 PF02290.15 KFP12094.1 - 9.9e-25 86.7 0.1 9.9e-25 86.7 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF3509 PF12021.8 KFP12094.1 - 0.093 12.5 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) BMF PF15185.6 KFP12095.1 - 1.8e-115 383.4 1.2 2.1e-115 383.2 1.2 1.0 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis MoCF_biosynth PF00994.24 KFP12096.1 - 3e-67 224.7 0.0 3e-39 133.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KFP12096.1 - 6.1e-42 143.1 1.4 1.2e-41 142.1 0.5 1.9 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KFP12096.1 - 2.2e-23 82.2 0.0 5.8e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Tubulin-binding PF00418.19 KFP12096.1 - 0.18 11.9 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat DUF3699 PF12480.8 KFP12099.1 - 1.2e-21 76.7 1.4 2.1e-21 75.9 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3699) Guanylate_kin PF00625.21 KFP12100.1 - 6.7e-52 175.8 0.0 1.5e-51 174.7 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase L27_N PF09060.10 KFP12100.1 - 3e-25 88.0 3.3 9.4e-25 86.4 3.3 1.9 1 0 0 1 1 1 1 L27_N SH3_2 PF07653.17 KFP12100.1 - 2.1e-12 46.5 0.0 4.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KFP12100.1 - 1.2e-11 44.8 0.6 2.4e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KFP12100.1 - 1.6e-09 37.4 1.5 1.6e-09 37.4 1.5 2.1 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 KFP12100.1 - 2.4e-09 36.9 0.0 6.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFP12100.1 - 2e-06 27.3 0.3 7.1e-06 25.5 0.3 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.6 KFP12100.1 - 6.1e-06 26.5 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFP12100.1 - 0.0003 20.6 0.1 0.00067 19.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.23 KFP12100.1 - 0.03 14.4 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SpoU_sub_bind PF08032.12 KFP12100.1 - 7.2 7.0 6.1 16 5.8 0.0 3.9 4 1 1 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding ATP-synt_D PF01813.17 KFP12101.1 - 2.2e-76 256.1 7.9 2.6e-76 255.8 7.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF4249 PF14054.6 KFP12101.1 - 0.01 15.5 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) EIF_2_alpha PF07541.12 KFP12102.1 - 1.1e-36 125.4 0.0 2.2e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFP12102.1 - 1.1e-15 57.7 0.7 2.7e-15 56.5 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain SoDot-IcmSS PF16848.5 KFP12102.1 - 0.069 13.1 0.5 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 Substrate of the Dot/Icm secretion system, putative DUF4453 PF14627.6 KFP12102.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) PH PF00169.29 KFP12103.1 - 1.7e-35 121.7 0.1 1.4e-17 64.1 0.1 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.21 KFP12103.1 - 4.1e-17 62.0 0.0 1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.6 KFP12103.1 - 4.6e-08 33.4 3.9 0.026 15.0 0.0 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 KFP12103.1 - 2.1e-07 31.3 0.7 0.049 14.0 0.0 3.4 3 2 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 KFP12103.1 - 0.00048 20.3 0.7 0.21 11.9 0.3 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KFP12103.1 - 0.0028 17.9 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFP12103.1 - 0.0083 16.5 0.0 7.3 7.0 0.0 2.7 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_4 PF15404.6 KFP12103.1 - 0.028 14.2 0.2 7.9 6.2 0.0 3.4 4 0 0 4 4 4 0 Pleckstrin homology domain Gal-bind_lectin PF00337.22 KFP12104.1 - 1.9e-32 111.6 0.0 2.1e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin SBD PF17882.1 KFP12105.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 OAA-family lectin sugar binding domain FYVE PF01363.21 KFP12106.1 - 7.5e-16 58.0 19.1 1.5e-15 57.1 19.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger MerR-DNA-bind PF09278.11 KFP12106.1 - 0.061 13.9 0.0 0.24 12.0 0.0 2.1 1 0 0 1 1 1 0 MerR, DNA binding FYVE_2 PF02318.16 KFP12106.1 - 0.59 10.4 13.6 1.6 9.0 13.6 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger TPR_2 PF07719.17 KFP12107.1 - 0.00048 20.0 0.6 0.0024 17.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat adh_short PF00106.25 KFP12108.1 - 8.3e-31 107.0 0.1 6e-30 104.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP12108.1 - 1.4e-17 64.1 0.2 3.4e-17 62.8 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP12108.1 - 1e-07 32.0 0.2 1.5e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFP12108.1 - 0.00042 20.6 0.4 0.00074 19.8 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFP12108.1 - 0.022 14.2 0.2 0.051 13.0 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family V-SNARE_C PF12352.8 KFP12109.1 - 3.3e-20 72.1 7.9 3.3e-20 72.1 7.9 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFP12109.1 - 5.6e-13 49.1 5.8 5.6e-13 49.1 5.8 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KFP12109.1 - 1.3e-05 25.0 1.2 1.3e-05 25.0 1.2 1.8 2 0 0 2 2 2 1 Sec20 YqjK PF13997.6 KFP12109.1 - 0.0093 16.2 3.3 0.71 10.2 0.0 2.5 3 0 0 3 3 3 2 YqjK-like protein DUF745 PF05335.13 KFP12109.1 - 0.022 14.5 4.1 0.39 10.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fusion_gly PF00523.18 KFP12109.1 - 0.039 12.2 2.8 0.068 11.4 2.8 1.4 1 1 0 1 1 1 0 Fusion glycoprotein F0 Laminin_II PF06009.12 KFP12109.1 - 0.043 13.8 4.6 0.069 13.2 0.7 2.3 2 1 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.6 KFP12109.1 - 0.055 13.9 10.9 0.091 13.2 1.2 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF3958 PF13125.6 KFP12109.1 - 0.61 10.3 10.6 0.11 12.7 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) HalX PF08663.10 KFP12109.1 - 0.84 10.0 8.3 4.4 7.7 2.1 2.4 2 0 0 2 2 2 0 HalX domain RSS_P20 PF11757.8 KFP12109.1 - 0.9 10.0 6.9 0.31 11.5 1.1 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain KxDL PF10241.9 KFP12109.1 - 3.5 8.0 10.1 4.1 7.8 1.3 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein UPF0242 PF06785.11 KFP12109.1 - 5.1 7.2 12.3 4.5 7.3 1.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Arginase PF00491.21 KFP12110.1 - 8.6e-67 225.6 0.0 1e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family PIG-H PF10181.9 KFP12111.1 - 4.5e-10 39.2 0.1 7.3e-10 38.6 0.1 1.4 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ABC_trans_CmpB PF06541.11 KFP12112.1 - 3.6e-09 37.0 9.6 4.4e-09 36.7 9.6 1.1 1 0 0 1 1 1 1 Putative ABC-transporter type IV Rad51 PF08423.11 KFP12113.1 - 4.9e-38 130.9 0.0 5.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFP12113.1 - 1.8e-10 40.7 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFP12113.1 - 3.2e-07 29.9 1.5 5.1e-06 26.0 1.5 2.3 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFP12113.1 - 2.5e-05 23.9 0.1 0.013 14.9 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 KFP12113.1 - 3.4e-05 23.3 0.1 0.00071 19.0 0.1 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain DUF5522 PF17653.1 KFP12113.1 - 0.033 14.1 0.2 0.082 12.9 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5522) PAXNEB PF05625.11 KFP12113.1 - 0.051 12.7 0.1 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein AAA_24 PF13479.6 KFP12113.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFP12113.1 - 0.12 12.8 0.2 0.41 11.1 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRM_1 PF00076.22 KFP12118.1 - 5.5e-34 115.8 0.1 1.6e-16 59.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP12118.1 - 2e-08 34.2 0.3 9.2e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 KFP12118.1 - 6.7e-06 25.7 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP12118.1 - 9.5e-05 22.2 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFP12118.1 - 0.0073 16.3 0.2 0.066 13.2 0.1 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KFP12118.1 - 0.037 14.0 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain SET_assoc PF11767.8 KFP12118.1 - 0.098 12.3 0.2 1 9.1 0.1 2.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Presenilin PF01080.17 KFP12118.1 - 2.3 6.9 8.5 2.7 6.6 8.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KFP12118.1 - 2.3 6.4 14.0 2.7 6.2 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Spectrin PF00435.21 KFP12119.1 - 1.3e-74 247.4 25.4 1.1e-25 90.2 6.9 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFP12119.1 - 2e-50 169.5 0.1 4.4e-25 88.0 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFP12119.1 - 8.2e-27 93.1 0.0 3.4e-26 91.1 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFP12119.1 - 2.4e-07 29.8 1.0 0.0097 15.4 0.2 3.3 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 KFP12119.1 - 9.2e-07 28.6 0.0 5e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.6 KFP12119.1 - 2e-06 28.1 0.1 1.6e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP12119.1 - 6.6e-05 22.7 1.1 0.002 18.0 0.4 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP12119.1 - 0.0003 20.5 1.8 0.03 14.2 0.1 3.8 4 0 0 4 4 3 1 EF-hand domain XisI PF08869.11 KFP12119.1 - 0.0092 16.3 0.9 0.033 14.5 0.9 2.0 1 0 0 1 1 1 1 XisI protein EF-hand_11 PF08976.11 KFP12119.1 - 0.078 13.9 0.2 0.34 11.8 0.1 2.2 2 0 0 2 2 1 0 EF-hand domain Uds1 PF15456.6 KFP12119.1 - 0.29 11.3 11.0 0.16 12.1 2.4 3.5 3 0 0 3 3 3 0 Up-regulated During Septation U3_assoc_6 PF08640.11 KFP12119.1 - 0.81 9.8 4.0 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 WD40 PF00400.32 KFP12120.1 - 1.1e-12 48.2 10.4 0.0047 17.7 0.1 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Frtz PF11768.8 KFP12120.1 - 0.059 11.7 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DNA_pol_A_exo1 PF01612.20 KFP12121.1 - 5.6e-16 58.8 0.0 9.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease RRXRR PF14239.6 KFP12121.1 - 0.011 15.7 0.0 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 RRXRR protein Glycos_transf_2 PF00535.26 KFP12122.1 - 2.1e-22 79.7 0.0 3.4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP12122.1 - 1.5e-17 64.1 2.5 2.6e-17 63.3 2.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP12122.1 - 2e-07 31.1 0.0 4.2e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFP12122.1 - 2.8e-06 27.0 0.1 1.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP12122.1 - 9.1e-06 25.2 0.1 1.8e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4227 PF14004.6 KFP12122.1 - 0.09 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF4897 PF16238.5 KFP12122.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) ER PF01133.17 KFP12123.1 - 5.9e-46 154.5 0.2 6.7e-46 154.3 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary BA14K PF07886.11 KFP12123.1 - 0.11 12.4 1.2 0.25 11.3 1.2 1.6 1 0 0 1 1 1 0 BA14K-like protein Zip PF02535.22 KFP12124.1 - 5.1e-40 137.7 18.3 6e-29 101.3 11.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter 7TM-7TMR_HD PF07698.11 KFP12124.1 - 1.2 8.8 12.1 0.18 11.6 4.8 2.5 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF996 PF06195.13 KFP12124.1 - 5.8 7.2 9.9 0.75 10.1 2.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF996) PH PF00169.29 KFP12126.1 - 5.9e-08 33.2 0.0 1.6e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Glyco_trans_1_2 PF13524.6 KFP12126.1 - 0.29 11.5 3.4 2.6 8.5 0.2 2.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Baculo_PEP_C PF04513.12 KFP12126.1 - 4.2 7.4 10.9 3.9 7.5 2.3 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.19 KFP12126.1 - 4.7 7.0 70.5 0.015 15.2 28.4 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family NAPRTase_N PF17767.1 KFP12126.1 - 6.3 7.2 14.9 1.4 9.3 3.1 3.4 3 2 1 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Lebercilin PF15619.6 KFP12126.1 - 7.8 6.1 60.7 2.6 7.6 26.9 2.5 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4659 PF15558.6 KFP12127.1 - 9.3e-127 422.9 127.5 1.1e-126 422.7 127.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4659) Sushi PF00084.20 KFP12128.1 - 2.9e-07 31.0 6.3 4.8e-07 30.3 6.3 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) RRM_1 PF00076.22 KFP12130.1 - 2.1e-28 97.9 0.2 2.7e-13 49.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP12130.1 - 2.6e-06 27.4 0.2 0.00085 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFP12130.1 - 3.2e-05 23.8 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFP12130.1 - 0.0021 17.7 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP12130.1 - 0.0021 17.9 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DbpA PF03880.15 KFP12130.1 - 0.012 15.6 0.0 8.4 6.5 0.0 2.6 3 0 0 3 3 3 0 DbpA RNA binding domain ALMT PF11744.8 KFP12130.1 - 1.1 8.0 5.5 1.3 7.7 5.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Thyroglobulin_1 PF00086.18 KFP12131.1 - 1.6e-36 123.8 24.5 7.5e-20 70.4 4.8 3.2 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat Thyroglob_assoc PF16597.5 KFP12131.1 - 1.7e-26 92.3 1.0 4.2e-26 91.0 1.0 1.7 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain SPARC_Ca_bdg PF10591.9 KFP12131.1 - 1.2e-10 41.7 0.0 2.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.15 KFP12131.1 - 1.5e-07 31.4 7.2 1.5e-07 31.4 7.2 4.6 4 1 1 5 5 5 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP12131.1 - 0.00013 22.4 0.3 0.00028 21.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair Kazal_1 PF00050.21 KFP12131.1 - 0.0017 18.3 4.3 0.0017 18.3 4.3 3.4 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.6 KFP12131.1 - 0.0055 16.5 0.1 0.99 9.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP12131.1 - 0.016 14.8 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 KFP12131.1 - 0.042 13.3 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 EF hand Defensin_beta PF00711.19 KFP12131.1 - 8.6 6.5 9.4 9.8 6.3 0.5 3.7 3 0 0 3 3 3 0 Beta defensin Calx-beta PF03160.14 KFP12132.1 - 2.2e-62 207.5 9.0 8.6e-31 106.1 0.2 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.24 KFP12132.1 - 2.7e-58 196.2 35.8 3.1e-33 114.9 13.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KFP12132.1 - 2.2e-54 183.3 5.1 5e-54 182.2 5.1 1.6 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Acyl_transf_3 PF01757.22 KFP12132.1 - 0.52 9.3 26.3 0.28 10.2 12.2 2.5 2 0 0 2 2 2 0 Acyltransferase family Peptidase_C97 PF05903.14 KFP12134.1 - 1.2e-41 142.0 0.0 1.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3670 PF12419.8 KFP12134.1 - 0.21 11.4 0.0 0.61 9.9 0.0 1.7 2 0 0 2 2 2 0 SNF2 Helicase protein PDZ PF00595.24 KFP12135.1 - 4.3e-20 71.9 0.3 5.9e-20 71.4 0.0 1.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP12135.1 - 3.1e-10 39.7 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP12135.1 - 6.7e-08 32.8 0.1 7.9e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFP12135.1 - 0.042 13.8 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain Med6 PF04934.14 KFP12136.1 - 4.4e-44 149.5 0.1 5.9e-44 149.1 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Peptidase_M15 PF01427.17 KFP12136.1 - 0.0051 16.6 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 D-ala-D-ala dipeptidase SAM_decarbox PF01536.16 KFP12136.1 - 0.043 12.8 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Ten1_2 PF15490.6 KFP12136.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.4 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit Tim44 PF04280.15 KFP12137.1 - 4e-32 111.3 0.0 5.4e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 KFP12137.1 - 0.0026 16.9 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein ChaB PF06150.12 KFP12137.1 - 0.055 14.0 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 ChaB Peptidase_M1 PF01433.20 KFP12138.1 - 1.9e-92 308.7 0.5 3.1e-92 308.1 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFP12138.1 - 1.2e-86 291.2 0.0 7.1e-86 288.6 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFP12138.1 - 1.8e-51 175.0 0.2 3.3e-51 174.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT PF02985.22 KFP12139.1 - 3.4e-18 64.2 6.5 4.1e-05 23.5 0.0 9.3 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFP12139.1 - 1.1e-15 57.8 4.1 2.5e-11 43.8 0.0 6.4 7 1 1 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 KFP12139.1 - 1.5e-10 40.8 0.6 1.8e-09 37.4 0.0 3.0 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KFP12139.1 - 1.7e-08 34.7 0.2 0.00079 19.8 0.0 5.3 2 2 3 5 5 5 3 HEAT repeats Arm PF00514.23 KFP12139.1 - 1.3e-07 31.4 6.4 0.0031 17.5 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFP12139.1 - 2.2e-05 24.5 3.8 0.014 15.5 0.0 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFP12139.1 - 5.6e-05 22.8 3.4 0.48 9.9 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal V-ATPase_H_C PF11698.8 KFP12139.1 - 0.12 12.4 5.3 0.6 10.2 0.3 3.4 3 0 0 3 3 3 0 V-ATPase subunit H 7tm_4 PF13853.6 KFP12140.1 - 1.3e-50 172.7 10.8 1.6e-50 172.4 10.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12140.1 - 2.7e-28 99.1 13.8 3.9e-28 98.5 13.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12140.1 - 0.0029 17.0 12.7 0.0045 16.4 12.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP12141.1 - 1.5e-22 80.7 1.0 1.6e-22 80.5 1.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12141.1 - 1.8e-05 24.2 4.5 2.4e-05 23.8 4.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Interferon PF00143.19 KFP12142.1 - 2.2e-37 128.7 0.0 2.5e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain Creb_binding PF09030.10 KFP12142.1 - 0.0027 18.4 0.8 0.004 17.8 0.8 1.4 1 0 0 1 1 1 1 Creb binding HTH_IclR PF09339.10 KFP12142.1 - 1.6 8.6 5.5 6 6.7 0.3 2.9 3 0 0 3 3 3 0 IclR helix-turn-helix domain UQ_con PF00179.26 KFP12143.1 - 6.9e-30 103.5 0.3 8.7e-30 103.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nrap_D4 PF17405.2 KFP12144.1 - 1.8e-54 184.3 0.0 3.4e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KFP12144.1 - 1.1e-51 174.8 0.7 2.5e-50 170.4 0.2 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 KFP12144.1 - 1.5e-48 164.7 0.1 3.1e-48 163.7 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 KFP12144.1 - 1.6e-43 148.1 1.5 8.1e-41 139.3 0.3 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KFP12144.1 - 2.2e-40 138.4 0.0 3.7e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KFP12144.1 - 3.5e-32 111.4 0.0 7.5e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 MIP PF00230.20 KFP12145.1 - 3.7e-52 177.3 13.1 4.6e-52 177.0 13.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 KFP12146.1 - 1.8e-43 148.9 10.9 2.3e-43 148.5 10.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3172 PF11371.8 KFP12146.1 - 0.035 13.8 0.8 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) RRM_1 PF00076.22 KFP12148.1 - 2.7e-37 126.4 0.0 1.5e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP12148.1 - 0.00038 20.0 0.0 0.26 10.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP12148.1 - 0.0036 17.3 0.0 0.14 12.1 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFP12148.1 - 0.013 15.5 0.0 1.8 8.6 0.0 2.9 2 1 0 2 2 2 0 RNA binding domain RRM_3 PF08777.11 KFP12148.1 - 0.024 14.7 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 KFP12148.1 - 0.03 14.5 0.0 11 6.2 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KFP12148.1 - 0.25 11.5 1.0 17 5.6 0.1 2.9 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TF_Otx PF03529.13 KFP12148.1 - 0.44 11.0 14.5 0.31 11.4 3.1 2.5 2 0 0 2 2 2 0 Otx1 transcription factor DUF3421 PF11901.8 KFP12149.1 - 3.5e-13 49.5 0.0 3.4e-11 43.1 0.0 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) zf-B_box PF00643.24 KFP12150.1 - 8.7e-11 41.8 7.5 1.1e-10 41.5 7.5 1.1 1 0 0 1 1 1 1 B-box zinc finger Eapp_C PF10238.9 KFP12150.1 - 0.016 15.3 2.3 0.018 15.1 2.3 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein IBR PF01485.21 KFP12150.1 - 0.21 11.8 4.8 0.41 10.9 4.8 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ank_2 PF12796.7 KFP12151.1 - 6e-34 116.5 2.7 3.6e-15 56.3 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP12151.1 - 2.1e-21 73.7 0.4 2.7e-06 27.3 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFP12151.1 - 9.9e-20 70.0 2.0 4.5e-07 30.0 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP12151.1 - 2e-18 66.2 1.3 3.8e-08 33.5 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP12151.1 - 2.1e-18 66.5 2.4 4.7e-11 43.0 0.4 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA_23 PF13476.6 KFP12151.1 - 0.027 15.0 1.3 0.043 14.3 1.3 1.4 1 0 0 1 1 1 0 AAA domain FA_desaturase PF00487.24 KFP12152.1 - 4.6e-33 115.1 24.1 1.2e-32 113.7 20.9 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 KFP12152.1 - 1.1e-21 76.7 0.0 2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHDNT PF08073.12 KFP12152.1 - 0.056 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 CHDNT (NUC034) domain Ets PF00178.22 KFP12153.1 - 9.6e-34 115.7 3.8 3.5e-33 113.9 0.6 2.5 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KFP12153.1 - 5.1e-25 87.2 3.1 8e-25 86.6 2.4 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Acetyltransf_2 PF00797.17 KFP12153.1 - 0.015 15.1 0.2 0.072 12.9 0.2 2.1 1 1 0 1 1 1 0 N-acetyltransferase fn3 PF00041.21 KFP12156.1 - 4e-89 293.1 13.3 7.6e-19 67.8 0.1 6.2 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.16 KFP12156.1 - 1.3e-64 214.3 9.5 2.9e-20 72.1 0.0 8.3 9 0 0 9 9 9 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12156.1 - 1.8e-46 156.6 1.3 1.8e-12 47.7 0.0 8.2 8 0 0 8 8 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFP12156.1 - 6e-31 106.6 1.6 1.5e-07 31.7 0.0 7.2 7 0 0 7 7 7 4 Immunoglobulin domain ig PF00047.25 KFP12156.1 - 3.9e-23 81.4 9.8 1.8e-08 34.4 0.0 8.1 8 0 0 8 8 8 5 Immunoglobulin domain V-set PF07686.17 KFP12156.1 - 3.1e-17 62.7 13.4 0.016 15.4 0.2 10.6 7 4 1 8 8 8 4 Immunoglobulin V-set domain Tissue_fac PF01108.17 KFP12156.1 - 3.4e-12 46.2 0.5 0.024 14.5 0.0 5.5 6 0 0 6 6 6 4 Tissue factor Pur_ac_phosph_N PF16656.5 KFP12156.1 - 1.1e-10 42.0 10.7 0.02 15.4 0.8 7.5 7 0 0 7 7 7 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP12156.1 - 4.1e-06 26.8 0.2 0.12 12.4 0.0 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 KFP12156.1 - 8e-06 26.0 0.5 0.24 11.6 0.0 4.8 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 fn3_2 PF16893.5 KFP12156.1 - 0.00099 19.2 0.3 8.1 6.7 0.0 4.2 3 1 0 3 3 3 2 Fibronectin type III domain Cadherin-like PF12733.7 KFP12156.1 - 0.067 13.7 1.4 10 6.7 0.1 3.4 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain GBP_C PF02841.14 KFP12156.1 - 1.4 8.2 6.1 2.3 7.6 6.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RhoGEF PF00621.20 KFP12159.1 - 1.5e-39 136.1 0.4 4.4e-39 134.6 0.4 1.9 1 0 0 1 1 1 1 RhoGEF domain GKAP PF03359.13 KFP12160.1 - 2.5e-160 533.7 1.1 2.5e-160 533.7 1.1 2.6 3 0 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein Pollen_allerg_2 PF01620.16 KFP12160.1 - 0.12 12.6 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) TraD PF06412.11 KFP12164.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Conjugal transfer protein TraD TDRP PF15683.5 KFP12166.1 - 1.4e-73 245.7 8.9 1.6e-73 245.5 8.9 1.0 1 0 0 1 1 1 1 Testis development-related protein Elongin_A PF06881.11 KFP12167.1 - 0.00024 21.6 0.1 0.00024 21.6 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 KFP12167.1 - 0.0034 17.2 0.1 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain FAM110_C PF14160.6 KFP12168.1 - 7.3e-36 123.7 0.6 7.3e-36 123.7 0.6 2.1 3 0 0 3 3 3 1 Centrosome-associated C terminus FAM110_N PF14161.6 KFP12168.1 - 1.5e-18 67.0 0.1 4.8e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Centrosome-associated N terminus LMWPc PF01451.21 KFP12169.1 - 5.3e-47 159.8 0.1 5.9e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TMEM206 PF15122.6 KFP12169.1 - 0.024 13.8 0.1 0.033 13.4 0.1 1.1 1 0 0 1 1 1 0 TMEM206 protein family FAM150 PF15129.6 KFP12170.1 - 5.8e-60 200.9 0.7 6.9e-60 200.6 0.7 1.1 1 0 0 1 1 1 1 FAM150 family TMEM18 PF14770.6 KFP12173.1 - 2.8e-46 156.4 5.4 3.2e-46 156.2 5.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 PDZ PF00595.24 KFP12177.1 - 9.8e-17 61.1 1.2 1.7e-16 60.3 1.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP12177.1 - 9.9e-10 38.1 0.2 2.4e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFP12177.1 - 5e-07 30.2 0.0 0.045 14.2 0.0 2.8 2 1 0 2 2 2 2 PH domain PDZ_2 PF13180.6 KFP12177.1 - 2.8e-05 24.3 0.1 7.4e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PH_17 PF18012.1 KFP12177.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Tricorn_PDZ PF14685.6 KFP12177.1 - 0.041 13.9 0.5 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain An_peroxidase PF03098.15 KFP12179.1 - 9.9e-188 625.0 0.0 1.2e-187 624.7 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_CA PF07645.15 KFP12179.1 - 2.7e-09 37.1 6.2 2.7e-09 37.1 6.2 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP12179.1 - 6e-06 26.4 6.8 6e-06 26.4 6.8 2.9 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP12179.1 - 2.9e-05 24.2 6.3 2.9e-05 24.2 6.3 2.3 2 0 0 2 2 2 1 EGF domain Sushi PF00084.20 KFP12179.1 - 8.5e-05 23.1 6.5 0.00028 21.4 6.5 2.0 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) cEGF PF12662.7 KFP12179.1 - 0.00089 19.1 7.0 0.046 13.7 0.5 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 KFP12179.1 - 0.012 15.9 4.4 0.012 15.9 4.4 3.0 3 0 0 3 3 3 0 EGF-like domain DNA_RNApol_7kD PF03604.13 KFP12179.1 - 0.3 10.8 2.0 0.52 10.0 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit hEGF PF12661.7 KFP12179.1 - 1.2 9.9 7.4 0.2 12.3 1.5 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF An_peroxidase PF03098.15 KFP12180.1 - 2.5e-195 650.1 0.0 4.3e-195 649.3 0.0 1.4 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 KFP12180.1 - 1.4e-87 287.8 0.5 1.2e-20 73.3 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12180.1 - 2e-77 255.8 6.3 4.4e-20 72.1 0.2 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP12180.1 - 3.8e-50 168.1 3.1 9.7e-12 45.1 0.1 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFP12180.1 - 3.9e-43 145.5 1.4 2.9e-13 49.8 0.1 4.7 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.6 KFP12180.1 - 5e-37 125.5 22.1 1.8e-17 62.9 3.6 3.7 1 1 2 3 3 3 3 Leucine rich repeat V-set PF07686.17 KFP12180.1 - 2.8e-23 82.2 12.4 0.0007 19.7 0.1 8.2 4 4 1 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP12180.1 - 3.2e-19 68.8 2.1 0.0011 19.0 0.0 4.7 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP12180.1 - 3.1e-16 59.6 0.3 0.0011 19.4 0.1 5.2 5 0 0 5 5 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_4 PF12799.7 KFP12180.1 - 1.7e-15 56.8 22.0 1.1e-06 28.8 3.0 5.4 4 1 4 8 8 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP12180.1 - 1.1e-10 41.6 1.6 2.5e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP12180.1 - 1.8e-10 40.6 2.5 3.6e-05 23.3 0.6 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Ig_6 PF18452.1 KFP12180.1 - 4.8e-10 38.8 0.0 0.45 10.1 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain Ig_4 PF16680.5 KFP12180.1 - 6.2e-10 39.2 0.0 0.013 15.8 0.1 4.9 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain VWC PF00093.18 KFP12180.1 - 5.5e-09 36.2 18.5 5.5e-09 36.2 18.5 2.9 3 0 0 3 3 2 1 von Willebrand factor type C domain Ig_C17orf99 PF17736.1 KFP12180.1 - 2.3e-07 30.7 0.0 0.16 12.0 0.0 4.1 4 0 0 4 4 4 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP12180.1 - 8.9e-06 25.7 0.4 5.8 7.0 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain PSP94 PF05825.11 KFP12180.1 - 0.00076 20.0 8.5 0.0022 18.5 8.5 1.7 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) LRR_1 PF00560.33 KFP12180.1 - 0.0025 18.1 9.9 9.6 7.2 0.2 5.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRRCT PF01463.24 KFP12180.1 - 0.0033 17.9 0.1 0.033 14.7 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain Amnionless PF14828.6 KFP12180.1 - 0.0067 15.3 9.5 0.011 14.6 9.5 1.2 1 0 0 1 1 1 1 Amnionless TILa PF12714.7 KFP12180.1 - 0.0086 16.0 11.1 0.0086 16.0 11.1 2.3 2 0 0 2 2 1 1 TILa domain CFC PF09443.10 KFP12180.1 - 0.11 12.4 4.2 0.37 10.7 4.2 2.0 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) DUF3573 PF12097.8 KFP12180.1 - 0.3 9.9 0.6 0.46 9.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) fn1 PF00039.18 KFP12180.1 - 1.6 9.0 6.3 6.8 7.0 6.3 2.2 1 0 0 1 1 1 0 Fibronectin type I domain WD40 PF00400.32 KFP12182.1 - 2.7e-16 59.7 7.7 1.5e-05 25.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat TPR_2 PF07719.17 KFP12184.1 - 1.5e-12 46.6 0.0 0.0046 17.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP12184.1 - 1e-11 44.1 0.1 0.0024 17.6 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP12184.1 - 8.7e-09 35.5 0.3 0.00019 21.7 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP12184.1 - 2.1e-06 28.2 0.0 0.017 15.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP12184.1 - 1.2e-05 25.8 0.0 0.047 14.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP12184.1 - 2.7e-05 24.5 0.1 0.004 17.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP12184.1 - 0.0016 18.7 0.8 0.99 9.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP12184.1 - 0.0032 17.6 0.0 4.7 7.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFP12184.1 - 0.0071 15.8 0.3 0.016 14.6 0.1 1.6 2 0 0 2 2 2 1 Coatomer epsilon subunit ANAPC3 PF12895.7 KFP12184.1 - 0.02 15.1 0.7 0.54 10.5 0.1 2.8 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KFP12184.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 MalT-like TPR region HrpB1_HrpK PF09613.10 KFP12184.1 - 0.078 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 KFP12184.1 - 0.093 13.6 0.0 59 4.9 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP12184.1 - 0.096 12.8 0.0 12 6.3 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Herpes_BBRF1 PF04793.12 KFP12184.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 BRRF1-like protein ARD PF03079.14 KFP12185.1 - 1.2e-48 165.3 0.3 1.3e-48 165.1 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KFP12185.1 - 1.2e-08 34.6 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KFP12185.1 - 1.7e-05 24.7 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.6 KFP12185.1 - 0.0053 16.5 0.0 0.056 13.2 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 KFP12185.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KFP12185.1 - 0.054 13.2 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_H PF00075.24 KFP12186.1 - 2.3e-46 157.5 0.0 3.4e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFP12186.1 - 0.00031 20.5 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like MafB19-deam PF14437.6 KFP12186.1 - 0.086 12.6 0.8 0.14 11.9 0.3 1.7 1 1 1 2 2 2 0 MafB19-like deaminase Ribosomal_S7e PF01251.18 KFP12187.1 - 4.5e-94 313.4 4.1 5.1e-94 313.2 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Lectin_C PF00059.21 KFP12188.1 - 1.5e-17 64.3 0.0 2.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.18 KFP12188.1 - 1.1e-14 53.9 53.2 1e-08 34.8 23.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) HMG_box PF00505.19 KFP12193.1 - 2.2e-26 92.1 3.5 4.3e-26 91.1 3.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP12193.1 - 6e-09 36.4 0.6 1.5e-08 35.1 0.6 1.7 1 0 0 1 1 1 1 HMG-box domain DUF3275 PF11679.8 KFP12193.1 - 0.36 10.8 2.5 0.33 10.9 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) Folate_rec PF03024.14 KFP12194.1 - 1.5e-63 213.7 26.5 1.9e-63 213.4 26.5 1.1 1 0 0 1 1 1 1 Folate receptor family Globin PF00042.22 KFP12195.1 - 2.7e-30 105.1 0.0 4.8e-30 104.3 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.22 KFP12196.1 - 2.3e-29 102.1 0.0 2.6e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Globin Big_8 PF17961.1 KFP12196.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig domain Globin PF00042.22 KFP12197.1 - 4.6e-30 104.4 0.0 9.8e-30 103.4 0.0 1.5 2 0 0 2 2 2 1 Globin Big_8 PF17961.1 KFP12197.1 - 0.021 15.0 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig domain DUF2690 PF10901.8 KFP12197.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) Globin PF00042.22 KFP12198.1 - 4.9e-29 101.1 0.0 7.5e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Globin 7tm_4 PF13853.6 KFP12199.1 - 3.2e-118 394.5 24.5 3.6e-118 394.3 24.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12199.1 - 2.6e-23 82.7 20.1 3.3e-23 82.4 20.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12199.1 - 3.6e-08 33.1 21.8 7e-08 32.2 21.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Sh_2 PF17512.2 KFP12199.1 - 0.63 9.8 4.0 0.24 11.2 1.3 1.7 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein DUF2208 PF09973.9 KFP12199.1 - 1.7 8.2 9.7 0.057 13.0 1.5 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) Ribonuc_red_lgC PF02867.15 KFP12200.1 - 2e-171 571.1 0.0 2.5e-171 570.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFP12200.1 - 1e-22 79.9 0.0 2.6e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFP12200.1 - 1.6e-13 51.0 0.0 3.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain RhoGAP PF00620.27 KFP12201.1 - 1.2e-46 158.3 0.4 1.3e-45 155.0 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KFP12201.1 - 3.7e-17 62.4 6.5 8.3e-17 61.2 5.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP12201.1 - 4.9e-10 38.8 0.0 9.2e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP12201.1 - 7.8e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP12201.1 - 1.1e-08 34.7 0.0 2.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DASH_Dad3 PF08656.10 KFP12201.1 - 0.38 10.9 3.3 12 6.1 1.4 3.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 FlaC_arch PF05377.11 KFP12201.1 - 0.58 10.6 6.1 0.2 12.1 1.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) C12orf66_like PF09404.10 KFP12202.1 - 1.4e-206 686.6 7.8 1.5e-206 686.4 7.7 1.0 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like DUF5311 PF17238.2 KFP12202.1 - 0.043 13.7 0.3 0.07 13.0 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) RNase_3_N PF18497.1 KFP12202.1 - 0.053 13.7 1.6 1.1 9.5 0.1 2.7 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain Urb2 PF10441.9 KFP12202.1 - 0.057 13.3 0.6 0.13 12.2 0.3 1.6 1 1 0 1 1 1 0 Urb2/Npa2 family Pox_I1 PF03289.13 KFP12202.1 - 0.06 12.5 0.5 0.48 9.5 0.1 2.1 2 0 0 2 2 2 0 Poxvirus protein I1 DUF3867 PF12983.7 KFP12202.1 - 0.079 13.0 0.2 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Ribosomal_L18A PF01775.17 KFP12203.1 - 1.1e-56 190.1 0.0 1.4e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Xpo1 PF08389.12 KFP12204.1 - 2.9e-38 131.3 7.5 8e-37 126.6 1.1 4.2 3 1 0 3 3 3 2 Exportin 1-like protein HEAT PF02985.22 KFP12204.1 - 0.02 15.1 0.2 5 7.6 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Csm2_III-A PF03750.13 KFP12204.1 - 0.076 13.9 1.1 3.3 8.6 0.1 3.7 3 1 0 3 3 3 0 Csm2 Type III-A Phage_min_cap2 PF06152.11 KFP12204.1 - 0.39 9.6 1.6 0.62 8.9 0.3 1.8 2 0 0 2 2 2 0 Phage minor capsid protein 2 TBK1_CCD1 PF18394.1 KFP12205.1 - 1.8e-120 401.3 4.6 2.6e-120 400.8 4.6 1.3 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase PF00069.25 KFP12205.1 - 1.4e-45 155.8 0.0 2.8e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TBK1_ULD PF18396.1 KFP12205.1 - 1.5e-37 127.4 4.2 2.7e-37 126.6 1.6 2.4 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Pkinase_Tyr PF07714.17 KFP12205.1 - 5.6e-26 91.4 0.0 1.3e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP12205.1 - 9.8e-07 27.9 0.0 4.7e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFP12205.1 - 0.00012 21.5 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like ubiquitin PF00240.23 KFP12205.1 - 0.0023 17.6 0.4 0.0062 16.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family NPV_P10 PF05531.12 KFP12205.1 - 0.0038 17.7 0.2 0.91 10.0 0.1 2.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Dynactin PF12455.8 KFP12205.1 - 0.013 14.8 0.4 0.24 10.6 0.0 2.3 2 0 0 2 2 2 0 Dynein associated protein C1_1 PF00130.22 KFP12207.1 - 0.054 13.4 5.3 0.077 12.9 5.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 KFP12208.1 - 5.2e-22 78.3 0.2 4.3e-21 75.4 0.2 2.1 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFP12208.1 - 9e-16 57.5 3.4 9e-16 57.5 3.4 1.9 2 0 0 2 2 2 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Ras_bdg_2 PF14847.6 KFP12208.1 - 0.029 14.7 0.1 0.058 13.7 0.1 1.7 1 1 0 1 1 1 0 Ras-binding domain of Byr2 Mst1_SARAH PF11629.8 KFP12208.1 - 0.068 13.3 1.0 0.14 12.2 1.0 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Sulfatase PF00884.23 KFP12209.1 - 3.5e-62 210.6 0.2 4.3e-62 210.3 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP12209.1 - 3e-07 30.4 0.0 0.0032 17.1 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFP12209.1 - 1.8e-05 25.0 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) DUF4682 PF15733.5 KFP12210.1 - 6.9e-44 149.5 3.2 6.9e-44 149.5 3.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4682) RabGAP-TBC PF00566.18 KFP12210.1 - 1.5e-36 126.1 1.2 2e-36 125.7 0.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain 60KD_IMP PF02096.20 KFP12210.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.8 4 0 0 4 4 4 0 60Kd inner membrane protein EGF_2 PF07974.13 KFP12211.1 - 1.6e-19 69.9 92.2 0.00031 21.1 5.1 5.3 5 0 0 5 5 5 5 EGF-like domain WIF PF02019.18 KFP12211.1 - 5.2e-15 55.3 0.0 7.2e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 WIF domain hEGF PF12661.7 KFP12211.1 - 1.8e-12 47.4 65.6 0.00039 20.9 6.5 6.3 5 1 0 5 5 5 5 Human growth factor-like EGF EGF PF00008.27 KFP12211.1 - 3.4e-11 43.2 88.1 0.00036 20.7 8.6 5.5 5 0 0 5 5 5 4 EGF-like domain DSL PF01414.19 KFP12211.1 - 0.041 14.2 9.1 0.041 14.2 9.1 3.9 2 2 1 3 3 3 0 Delta serrate ligand Laminin_EGF PF00053.24 KFP12211.1 - 3.4 7.9 72.3 4.3 7.5 9.3 5.3 1 1 4 5 5 5 0 Laminin EGF domain SelR PF01641.18 KFP12212.1 - 7.8e-54 180.9 0.2 9.9e-54 180.6 0.2 1.1 1 0 0 1 1 1 1 SelR domain zf-ribbon_3 PF13248.6 KFP12212.1 - 0.0048 16.3 1.0 0.49 9.9 0.1 2.8 2 0 0 2 2 2 1 zinc-ribbon domain Yippee-Mis18 PF03226.14 KFP12212.1 - 0.022 15.0 0.1 0.059 13.6 0.1 1.8 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KFP12212.1 - 0.036 14.1 0.3 0.35 10.9 0.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 KFP12212.1 - 0.041 13.8 1.0 0.56 10.2 1.0 2.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 KFP12212.1 - 0.066 13.3 3.3 0.21 11.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.14 KFP12212.1 - 0.073 13.4 1.4 1.4 9.3 0.4 2.4 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 KFP12212.1 - 0.099 12.4 0.8 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_2 PF13240.6 KFP12212.1 - 0.69 9.7 4.1 8 6.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-tcix PF14952.6 KFP12212.1 - 1.1 8.9 6.5 25 4.6 0.2 3.3 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding AT_hook PF02178.19 KFP12217.1 - 0.0079 16.0 27.1 0.079 12.9 7.2 3.2 3 1 0 3 3 3 2 AT hook motif RRM_1 PF00076.22 KFP12218.1 - 8.9e-67 220.9 7.5 3.2e-17 62.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KFP12218.1 - 0.00015 21.6 0.8 0.18 11.6 0.1 3.9 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KFP12218.1 - 0.0016 18.5 0.0 6 7.1 0.0 3.8 3 0 0 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 KFP12218.1 - 0.0018 18.3 1.3 1.8 8.7 0.0 4.0 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 KFP12218.1 - 0.0023 17.8 0.3 0.7 9.8 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif DbpA PF03880.15 KFP12218.1 - 0.02 14.8 0.2 0.64 10.0 0.0 3.1 4 0 0 4 4 4 0 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 KFP12218.1 - 0.057 13.4 0.1 2.6 8.1 0.1 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KFP12218.1 - 0.088 12.5 0.0 20 4.9 0.0 3.0 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated GMP_PDE_delta PF05351.11 KFP12219.1 - 6.1e-44 149.9 0.1 1e-43 149.1 0.1 1.3 1 1 0 1 1 1 1 GMP-PDE, delta subunit CSN7a_helixI PF18392.1 KFP12221.1 - 6e-23 80.5 2.6 1.1e-22 79.6 2.6 1.5 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFP12221.1 - 1.2e-09 38.6 3.4 3.1e-09 37.3 0.3 2.2 2 0 0 2 2 2 1 PCI domain Band_3_cyto PF07565.13 KFP12221.1 - 0.03 14.1 5.2 0.057 13.2 5.2 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RNB PF00773.19 KFP12223.1 - 1.8e-99 333.2 0.0 2.4e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFP12223.1 - 9.7e-26 89.6 0.0 3.1e-25 88.0 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KFP12223.1 - 2.6e-25 88.6 0.0 5.2e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 KFP12223.1 - 1.4e-07 31.3 0.0 1.2e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Rrp44-like cold shock domain CSD2 PF17876.1 KFP12223.1 - 5.5e-05 23.3 0.0 0.041 14.0 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 KFP12223.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Trypsin PF00089.26 KFP12224.1 - 1e-43 149.7 0.0 1.1e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP12224.1 - 0.0058 17.5 0.1 0.011 16.7 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Neur_chan_LBD PF02931.23 KFP12225.1 - 1.3e-71 240.5 3.8 1.9e-71 239.9 3.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP12225.1 - 2.3e-70 237.4 0.3 2.9e-70 237.0 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region IF4E PF01652.18 KFP12226.1 - 2.7e-60 202.8 0.1 3.3e-60 202.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.22 KFP12228.1 - 3.9e-119 398.4 0.0 4.5e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP12229.1 - 3.9e-122 408.3 0.2 4.4e-122 408.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_10 PF05176.14 KFP12229.1 - 0.0076 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein MCM6_C PF18263.1 KFP12229.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Peptidase_C2 PF00648.21 KFP12230.1 - 2.3e-80 269.8 0.0 3.3e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP12230.1 - 1.2e-44 151.9 0.0 4e-22 79.0 0.0 2.6 2 1 0 2 2 2 2 Calpain large subunit, domain III W2 PF02020.18 KFP12231.1 - 5.9e-19 68.0 2.3 5.9e-19 68.0 2.3 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFP12231.1 - 4.6e-12 45.2 7.1 0.00044 19.9 0.5 3.8 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFP12231.1 - 0.0079 14.4 0.6 0.013 13.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFP12231.1 - 0.028 13.4 0.6 0.052 12.5 0.6 1.4 1 0 0 1 1 1 0 L-fucokinase DUF4007 PF13182.6 KFP12231.1 - 0.038 13.1 0.3 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) VIR_N PF15912.5 KFP12231.1 - 0.083 12.5 3.2 0.14 11.7 3.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Hexapep_2 PF14602.6 KFP12231.1 - 1.6 8.5 11.6 4.3 7.2 0.2 3.8 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dsh_C PF12316.8 KFP12232.1 - 4e-80 269.1 33.4 4e-80 269.1 33.4 2.6 2 1 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.15 KFP12232.1 - 6.4e-67 225.0 22.5 6.4e-67 225.0 22.5 2.6 3 0 0 3 3 3 1 Dishevelled specific domain PDZ PF00595.24 KFP12232.1 - 8.8e-19 67.6 0.3 1.5e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 KFP12232.1 - 3.3e-17 62.3 0.0 7.1e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DIX PF00778.17 KFP12232.1 - 7.9e-06 25.6 0.1 3.3e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 DIX domain PDZ_6 PF17820.1 KFP12232.1 - 4.4e-05 23.2 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP12232.1 - 0.0061 16.9 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFP12232.1 - 0.029 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Adap_comp_sub PF00928.21 KFP12233.1 - 7.3e-82 274.7 0.1 9.4e-82 274.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP12233.1 - 7.1e-06 26.0 0.5 1.2e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFP12233.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ABC_tran PF00005.27 KFP12234.1 - 2.9e-43 147.7 0.2 1.5e-20 74.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KFP12234.1 - 1.5e-23 82.6 5.5 1.5e-23 82.6 5.5 2.6 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KFP12234.1 - 1.6e-15 57.7 2.6 0.0013 18.6 0.0 4.9 5 1 1 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP12234.1 - 5.5e-13 48.9 0.1 0.00013 21.5 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFP12234.1 - 5.8e-08 32.8 0.6 0.0037 17.0 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KFP12234.1 - 5.1e-06 26.8 1.3 0.027 14.7 0.0 3.3 3 2 0 3 3 2 2 AAA domain AAA PF00004.29 KFP12234.1 - 1.4e-05 25.6 0.7 0.2 12.1 0.0 3.5 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFP12234.1 - 1.4e-05 25.1 0.1 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KFP12234.1 - 2.7e-05 24.8 6.0 0.39 11.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 KFP12234.1 - 4.1e-05 23.6 0.1 0.043 13.9 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFP12234.1 - 8.1e-05 22.3 0.1 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP12234.1 - 0.00012 22.0 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KFP12234.1 - 0.00027 20.7 0.0 0.99 9.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KFP12234.1 - 0.00035 21.0 0.2 0.72 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KFP12234.1 - 0.0015 18.3 0.2 1 9.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 KFP12234.1 - 0.0017 18.5 3.7 0.29 11.2 0.0 3.4 4 0 0 4 4 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 KFP12234.1 - 0.0028 18.0 0.0 0.59 10.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KFP12234.1 - 0.0038 16.4 0.0 0.5 9.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 KFP12234.1 - 0.0059 16.7 1.6 0.071 13.2 0.0 3.0 2 1 0 2 2 2 1 Dynamin family Roc PF08477.13 KFP12234.1 - 0.006 16.8 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KFP12234.1 - 0.01 16.1 0.6 11 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KFP12234.1 - 0.013 15.5 0.3 3.3 7.8 0.0 3.5 3 1 1 4 4 4 0 AAA domain MobB PF03205.14 KFP12234.1 - 0.015 15.2 0.1 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFP12234.1 - 0.016 15.1 0.0 7.5 6.4 0.0 2.9 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 KFP12234.1 - 0.017 15.3 0.5 2.1 8.7 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 KFP12234.1 - 0.018 15.0 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFP12234.1 - 0.018 15.6 1.4 1.5 9.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_13 PF13166.6 KFP12234.1 - 0.025 13.3 0.7 3.2 6.3 0.0 3.1 2 1 1 3 3 3 0 AAA domain Septin PF00735.18 KFP12234.1 - 0.027 13.8 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Septin DUF1672 PF07901.11 KFP12234.1 - 0.045 13.1 0.9 0.076 12.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Arf PF00025.21 KFP12234.1 - 0.065 12.7 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 KFP12234.1 - 0.076 12.8 0.1 9.1 6.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP12234.1 - 0.078 12.5 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KFP12234.1 - 0.086 11.8 0.0 2 7.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KFP12234.1 - 0.13 11.9 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KFP12234.1 - 0.14 11.8 0.1 8.6 5.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KFP12234.1 - 0.23 11.6 4.5 3.1 7.9 0.0 3.3 4 1 0 4 4 2 0 AAA domain VIT_2 PF13757.6 KFP12235.1 - 2e-29 101.3 0.0 2.2e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT PF08487.10 KFP12235.1 - 6.3e-05 23.2 0.0 7.1e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KFP12236.1 - 6.8e-08 32.6 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP12236.1 - 0.0014 19.2 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFP12236.1 - 0.0041 17.4 0.0 0.0058 16.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP12237.1 - 3.5e-05 23.8 0.0 6.5e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 von Willebrand factor type A domain ALG3 PF05208.13 KFP12238.1 - 6.4e-115 384.4 14.5 7.3e-115 384.2 14.5 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.6 KFP12238.1 - 8.2e-05 22.1 18.3 8.2e-05 22.1 18.3 1.6 1 1 0 2 2 2 1 EpsG family Peptidase_M13_N PF05649.13 KFP12240.1 - 1.9e-106 357.0 0.4 3.1e-75 254.2 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 KFP12240.1 - 1.5e-34 119.4 1.3 1.6e-34 119.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.18 KFP12240.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 RPN1_RPN2_N PF17781.1 KFP12241.1 - 9.6e-94 314.2 0.2 9.6e-94 314.2 0.2 2.3 3 1 0 3 3 3 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFP12241.1 - 2.5e-32 110.7 0.3 5.2e-32 109.7 0.3 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFP12241.1 - 3.2e-24 84.1 25.6 1.1e-06 28.7 0.1 8.8 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFP12241.1 - 1.8e-05 25.0 0.0 0.11 12.9 0.0 3.7 3 1 1 4 4 4 2 HEAT repeats THAP PF05485.12 KFP12241.1 - 0.028 15.3 0.6 0.061 14.3 0.6 1.4 1 0 0 1 1 1 0 THAP domain MIF4G PF02854.19 KFP12242.1 - 2.2e-68 230.0 9.6 2.2e-68 230.0 9.6 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KFP12242.1 - 1.5e-28 99.0 0.5 7.3e-28 96.8 0.2 2.4 2 1 0 2 2 2 1 MA3 domain CHRD PF07452.12 KFP12243.1 - 6.3e-06 27.2 0.0 6.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 CHRD domain CHRD PF07452.12 KFP12244.1 - 8.9e-29 100.8 0.2 2.5e-13 51.0 0.1 3.1 3 0 0 3 3 3 3 CHRD domain VWC PF00093.18 KFP12244.1 - 0.25 11.7 7.9 0.43 10.9 7.9 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain Amnionless PF14828.6 KFP12244.1 - 0.82 8.4 11.2 1.4 7.6 11.2 1.3 1 0 0 1 1 1 0 Amnionless EPO_TPO PF00758.18 KFP12245.1 - 3.8e-25 88.8 0.4 4.5e-25 88.5 0.4 1.1 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin RNA_pol_Rpb8 PF03870.15 KFP12246.1 - 8.4e-44 149.1 0.1 9.4e-44 149.0 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KFP12246.1 - 0.00037 20.5 0.0 0.031 14.3 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G RVT_1 PF00078.27 KFP12248.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C48 PF02902.19 KFP12249.1 - 6.5e-43 147.1 1.6 1.2e-42 146.2 1.6 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.11 KFP12249.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain Cystatin PF00031.21 KFP12250.1 - 1e-16 60.9 0.0 8.7e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Cystatin domain Cystatin PF00031.21 KFP12252.1 - 2.8e-41 139.7 0.8 5.4e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.17 KFP12252.1 - 8e-13 48.6 1.9 1.2e-06 28.8 0.2 2.1 2 0 0 2 2 2 2 Cathelicidin SQAPI PF16845.5 KFP12252.1 - 0.00011 22.4 0.0 0.00045 20.5 0.0 1.9 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Spp-24 PF07448.11 KFP12252.1 - 0.00053 20.1 1.0 0.065 13.4 0.1 2.3 2 0 0 2 2 2 2 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain CD45 PF12567.8 KFP12252.1 - 0.75 9.8 3.7 2.8 8.0 0.1 2.7 2 1 0 2 2 2 0 Leukocyte receptor CD45 Glyco_transf_8 PF01501.20 KFP12253.1 - 1.8e-19 70.3 0.2 2.1e-09 37.3 0.0 2.4 2 1 1 3 3 3 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFP12253.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 KFP12253.1 - 0.01 15.8 0.1 0.021 14.8 0.1 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase SNF2_N PF00176.23 KFP12254.1 - 1.2e-83 280.7 0.1 1.8e-83 280.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFP12254.1 - 1.6e-19 69.6 0.0 3.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFP12254.1 - 8.6e-14 51.8 0.0 3.6e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KFP12254.1 - 2.1e-08 33.9 8.9 6.2e-08 32.3 8.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP12254.1 - 2.5e-08 33.7 9.0 7e-08 32.2 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP12254.1 - 9.4e-08 31.8 7.1 2.5e-07 30.4 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP12254.1 - 3.8e-07 30.0 8.2 1.3e-06 28.3 8.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP12254.1 - 2.4e-06 27.4 7.6 7.1e-06 25.9 7.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP12254.1 - 3e-06 27.5 8.8 3e-06 27.5 8.8 2.4 2 0 0 2 2 2 1 Ring finger domain ResIII PF04851.15 KFP12254.1 - 4e-06 26.9 0.0 0.0091 16.0 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KFP12254.1 - 2e-05 24.4 8.3 5e-05 23.1 8.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP12254.1 - 3e-05 24.1 10.0 7.7e-05 22.8 10.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFP12254.1 - 0.00019 21.4 0.9 0.00054 20.0 0.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFP12254.1 - 0.00059 20.1 3.0 0.0023 18.2 3.0 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KFP12254.1 - 0.0067 16.2 4.7 0.023 14.5 4.7 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit AAA_34 PF13872.6 KFP12254.1 - 0.075 11.9 0.0 10 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 zf-RING_4 PF14570.6 KFP12254.1 - 0.21 11.4 3.3 0.52 10.2 3.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFP12254.1 - 0.24 11.2 5.5 0.62 9.8 5.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 KFP12254.1 - 2.8 7.9 6.4 0.88 9.5 3.1 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Tubulin PF00091.25 KFP12255.1 - 9.1e-68 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP12255.1 - 1e-51 174.4 0.0 1.6e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP12255.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Cu-oxidase_3 PF07732.15 KFP12257.1 - 1.4e-29 102.5 2.0 3.4e-09 36.7 0.0 5.2 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFP12257.1 - 6.8e-27 93.9 12.3 5.9e-15 55.2 3.6 6.2 6 1 0 6 6 6 4 Multicopper oxidase Cu-oxidase PF00394.22 KFP12257.1 - 1.6e-12 47.8 0.2 2.5e-06 27.7 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase VitD-bind_III PF09164.10 KFP12257.1 - 0.11 12.4 2.6 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 Vitamin D binding protein, domain III L6_membrane PF05805.12 KFP12258.1 - 2.7e-54 183.6 16.5 3e-54 183.5 16.5 1.0 1 0 0 1 1 1 1 L6 membrane protein L6_membrane PF05805.12 KFP12259.1 - 6.2e-70 234.7 17.5 7e-70 234.5 17.5 1.0 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.17 KFP12259.1 - 0.73 9.5 9.5 0.028 14.1 1.9 2.1 2 0 0 2 2 2 0 Yip1 domain L6_membrane PF05805.12 KFP12260.1 - 4.6e-75 251.4 16.9 5.3e-75 251.2 16.9 1.0 1 0 0 1 1 1 1 L6 membrane protein TFIIA PF03153.13 KFP12261.1 - 3.7 7.5 14.5 4.4 7.2 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COMM_domain PF07258.14 KFP12262.1 - 2.2e-18 66.1 1.6 4.9e-18 65.0 1.6 1.6 1 0 0 1 1 1 1 COMM domain HTH_1 PF00126.27 KFP12262.1 - 0.024 14.6 0.4 0.093 12.7 0.1 1.9 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SOCS PF12610.8 KFP12262.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Suppressor of cytokine signalling DUF5057 PF16480.5 KFP12262.1 - 0.11 11.8 0.3 0.24 10.7 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5057) Profilin PF00235.19 KFP12263.1 - 4.4e-13 49.6 0.0 4.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Profilin TSC22 PF01166.18 KFP12264.1 - 4.9e-27 94.0 5.8 5.8e-27 93.8 5.8 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family K-box PF01486.17 KFP12264.1 - 0.0018 18.4 1.0 0.0024 18.0 1.0 1.2 1 0 0 1 1 1 1 K-box region YabA PF06156.13 KFP12264.1 - 0.002 18.7 3.1 0.0021 18.6 3.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA DivIC PF04977.15 KFP12264.1 - 0.0055 16.4 3.1 0.0061 16.3 2.6 1.4 1 1 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFP12264.1 - 0.089 13.3 6.6 0.13 12.7 6.6 1.5 1 1 0 1 1 1 0 Cell division protein ZapB eIF2A PF08662.11 KFP12265.1 - 6.8e-78 261.0 1.2 1.2e-75 253.6 0.1 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A CRT10 PF08728.10 KFP12265.1 - 1.3 7.1 3.5 2 6.5 3.5 1.2 1 0 0 1 1 1 0 CRT10 SR-25 PF10500.9 KFP12265.1 - 1.9 8.1 13.9 2.8 7.5 13.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 KFP12265.1 - 9.1 6.7 10.7 16 6.0 10.7 1.3 1 0 0 1 1 1 0 AAA domain Rdx PF10262.9 KFP12266.1 - 3.2e-11 43.2 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family FAM194 PF14977.6 KFP12267.1 - 6.9e-58 195.3 0.0 8.3e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein Sina PF03145.16 KFP12268.1 - 5.3e-73 245.2 0.1 5.3e-73 245.2 0.1 1.3 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 KFP12268.1 - 0.022 14.6 11.2 0.079 12.8 11.2 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP12268.1 - 0.58 10.1 11.5 12 5.9 11.8 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP12268.1 - 0.79 9.6 9.9 2.5 8.1 9.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP12268.1 - 8.7 6.6 14.9 0.7 10.1 8.8 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4205 PF13898.6 KFP12269.1 - 2.1e-36 125.6 0.0 2.3e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Synaptobrevin PF00957.21 KFP12270.1 - 0.081 12.7 2.2 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF3671 PF12420.8 KFP12270.1 - 1.6 8.8 4.7 0.89 9.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function Med12-LCEWAV PF12145.8 KFP12271.1 - 1.9e-182 607.4 0.6 3e-182 606.7 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 KFP12271.1 - 9.1e-15 54.7 0.2 2.2e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 CNOT1_HEAT PF16418.5 KFP12271.1 - 0.16 12.0 3.7 8.7 6.4 0.1 4.2 5 0 0 5 5 5 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Cortex-I_coil PF09304.10 KFP12271.1 - 7.5 6.8 7.6 1.4 9.2 2.4 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil 7tm_1 PF00001.21 KFP12272.1 - 5.1e-30 104.7 22.3 6.1e-30 104.4 22.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP12272.1 - 6.5e-09 35.8 22.6 6.5e-09 35.8 22.6 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ni_hydr_CYTB PF01292.20 KFP12272.1 - 0.019 14.6 2.2 0.031 13.9 0.7 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 YtpI PF14007.6 KFP12272.1 - 0.037 14.2 10.6 0.82 9.9 0.1 3.9 2 1 1 3 3 3 0 YtpI-like protein DUF948 PF06103.11 KFP12272.1 - 0.13 12.6 0.0 1.6 9.0 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) OAD_gamma PF04277.13 KFP12272.1 - 0.17 12.5 0.3 0.17 12.5 0.3 2.7 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain SARAF PF06682.12 KFP12272.1 - 0.2 11.3 0.7 2.3 7.8 0.7 2.1 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Colicin_V PF02674.16 KFP12272.1 - 1 9.3 11.3 0.9 9.5 0.4 2.8 3 0 0 3 3 3 0 Colicin V production protein 7tm_1 PF00001.21 KFP12273.1 - 3e-34 118.6 17.9 3.6e-34 118.3 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1129 PF06570.11 KFP12273.1 - 5.9 6.3 7.7 2 7.8 4.6 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4064 PF13273.6 KFP12273.1 - 7.6 6.9 9.4 3.6 7.9 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.21 KFP12274.1 - 7e-43 146.8 20.3 1.1e-42 146.3 20.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pet100 PF09803.9 KFP12274.1 - 0.18 12.4 0.9 0.46 11.0 0.9 1.7 1 0 0 1 1 1 0 Pet100 7TM_GPCR_Srx PF10328.9 KFP12274.1 - 1.3 8.6 26.2 1 8.9 21.3 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx HA2 PF04408.23 KFP12278.1 - 9.1e-21 74.2 0.0 2.8e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP12278.1 - 2.1e-17 63.2 0.0 4.8e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP12278.1 - 1.3e-16 60.9 0.1 3.2e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP12278.1 - 9.9e-15 54.7 0.1 3.1e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP12278.1 - 1.1e-05 25.8 0.1 3.1e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP12278.1 - 0.0011 19.4 0.0 0.0052 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KFP12278.1 - 0.003 16.9 0.0 0.0085 15.5 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.6 KFP12278.1 - 0.016 15.3 0.5 0.38 10.8 0.5 2.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFP12278.1 - 0.025 15.1 0.1 0.025 15.1 0.1 2.6 1 1 1 2 2 1 0 AAA domain PhoH PF02562.16 KFP12278.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 KFP12278.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KFP12278.1 - 0.15 11.9 0.3 0.76 9.7 0.3 2.4 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFP12278.1 - 0.16 12.4 0.8 0.66 10.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 KFP12278.1 - 0.34 11.4 1.5 0.98 9.9 0.2 2.4 2 1 1 3 3 3 0 ABC transporter Peptidase_M13_N PF05649.13 KFP12280.1 - 1.1e-119 400.6 3.0 1.7e-119 399.9 3.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP12280.1 - 7.5e-72 241.2 0.1 1.2e-71 240.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 LCIB_C_CA PF18599.1 KFP12280.1 - 0.11 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases AAA_23 PF13476.6 KFP12280.1 - 0.57 10.6 8.6 0.069 13.6 3.0 2.0 2 0 0 2 2 2 0 AAA domain PI-PLC-X PF00388.19 KFP12281.1 - 1.9e-63 212.4 0.0 5.4e-63 210.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP12281.1 - 1.8e-40 137.9 0.9 6.1e-40 136.2 0.3 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KFP12281.1 - 4.8e-18 65.4 0.6 1.3e-17 64.0 0.1 2.2 2 0 0 2 2 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP12281.1 - 1e-15 57.9 0.0 2.7e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFP12281.1 - 1e-10 41.9 2.2 4.7e-10 39.8 0.4 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP12281.1 - 1.8e-09 36.4 2.1 3.9e-05 22.9 0.0 3.5 3 0 0 3 3 3 2 EF hand PH_12 PF16457.5 KFP12281.1 - 5.9e-07 30.1 0.0 2.4e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_10 PF14788.6 KFP12281.1 - 9.7e-07 28.6 3.3 3.3e-06 26.9 0.2 3.2 3 1 1 4 4 4 1 EF hand EF-hand_6 PF13405.6 KFP12281.1 - 1.6e-06 27.5 1.0 0.021 14.7 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP12281.1 - 1.8e-05 24.0 2.5 0.00045 19.6 0.1 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFP12281.1 - 7.5e-05 22.5 0.4 0.1 12.5 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair PH PF00169.29 KFP12281.1 - 0.0015 19.0 0.0 0.0041 17.6 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_4 PF12763.7 KFP12281.1 - 0.043 13.8 0.1 0.15 12.0 0.1 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP12281.1 - 0.053 13.8 0.1 0.22 11.8 0.1 2.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region GATase PF00117.28 KFP12282.1 - 6.5e-40 136.9 0.0 3.2e-39 134.7 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KFP12282.1 - 3.6e-18 65.4 0.0 9.9e-11 41.5 0.0 3.1 2 1 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.17 KFP12282.1 - 1.1e-12 47.7 0.1 8e-09 35.0 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KFP12282.1 - 4.1e-12 46.3 0.1 1.5e-11 44.4 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KFP12282.1 - 2.7e-08 33.6 0.1 2.7e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFP12282.1 - 3.7e-06 26.0 0.1 1.4e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 KFP12282.1 - 0.00028 20.7 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 KFP12282.1 - 0.00029 20.7 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 KFP12282.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 KFP12282.1 - 0.00092 18.8 0.1 0.0024 17.5 0.1 1.7 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 KFP12282.1 - 0.0022 17.4 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase rve PF00665.26 KFP12282.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain TRAP-gamma PF07074.12 KFP12283.1 - 1.7e-64 216.4 6.1 1.9e-64 216.3 6.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Renin_r PF07850.14 KFP12283.1 - 0.014 16.0 1.1 0.021 15.4 0.3 1.7 1 1 0 2 2 2 0 Renin receptor-like protein SPC25 PF06703.11 KFP12283.1 - 0.11 12.3 3.8 0.063 13.1 1.6 1.7 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CENP-F_leu_zip PF10473.9 KFP12284.1 - 0.0065 16.5 10.1 0.0065 16.5 10.1 2.8 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ly49 PF08391.10 KFP12284.1 - 0.022 15.1 5.6 0.022 15.1 5.6 2.8 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region T3SSipB PF16535.5 KFP12284.1 - 0.056 13.9 10.0 0.2 12.1 0.7 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB Fib_alpha PF08702.10 KFP12284.1 - 0.1 12.8 19.5 0.06 13.5 5.8 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KFP12284.1 - 0.31 9.9 28.5 0.14 11.0 9.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KFP12284.1 - 0.32 11.1 24.4 1.5 8.9 6.7 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 KFP12284.1 - 0.38 10.1 31.6 0.1 11.9 12.8 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KFP12284.1 - 0.43 10.0 29.5 0.048 13.1 21.1 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Mod_r PF07200.13 KFP12284.1 - 0.71 10.0 24.8 2.4 8.3 7.3 2.7 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 KFP12284.1 - 0.74 10.3 7.9 27 5.3 0.0 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KFP12284.1 - 3.2 8.4 23.4 5 7.8 2.4 3.7 1 1 1 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 KFP12284.1 - 4.2 7.4 14.6 1.9 8.5 2.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFP12284.1 - 4.5 7.7 23.7 7 7.1 7.2 2.5 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 KFP12284.1 - 5.9 7.4 26.9 0.41 11.2 9.4 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region RNR_Alpha PF17975.1 KFP12285.1 - 0.1 13.1 0.5 0.1 13.1 0.5 3.1 3 1 0 3 3 3 0 Ribonucleotide reductase alpha domain GAS PF13851.6 KFP12285.1 - 5.3 6.3 59.8 6.6 6.0 24.6 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFP12285.1 - 9.7 6.2 29.4 2.1 8.4 4.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Cyclin_N PF00134.23 KFP12287.1 - 1.3e-11 44.4 0.3 8.2e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP12287.1 - 9.7e-06 25.7 0.1 9.7e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFP12287.1 - 0.00041 20.3 0.4 0.24 11.5 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KFP12287.1 - 0.0055 17.1 0.1 0.02 15.3 0.1 1.8 1 1 0 1 1 1 1 Cyclin C-terminal domain PH PF00169.29 KFP12288.1 - 1.9e-12 47.6 0.6 5.6e-12 46.1 0.6 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP12288.1 - 0.0018 18.7 3.0 0.0095 16.3 3.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain TyrRSs_C PF16714.5 KFP12288.1 - 0.056 13.2 0.7 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain Pentaxin PF00354.17 KFP12289.1 - 3.3e-28 98.7 0.0 6.3e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP12289.1 - 1e-16 61.5 0.0 1.6e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PQ-loop PF04193.14 KFP12290.1 - 1e-17 63.6 0.8 1e-17 63.6 0.8 2.4 3 0 0 3 3 3 1 PQ loop repeat DUF2427 PF10348.9 KFP12290.1 - 0.06 13.2 1.0 0.34 10.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) MtN3_slv PF03083.16 KFP12290.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.5 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Mlf1IP PF10248.9 KFP12293.1 - 1.5e-75 253.0 9.6 1.7e-75 252.7 9.6 1.0 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein GTP_EFTU PF00009.27 KFP12294.1 - 1.9e-63 213.5 0.0 2.8e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFP12294.1 - 1e-35 122.2 0.2 3.1e-35 120.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KFP12294.1 - 1.6e-31 108.2 0.0 3.6e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFP12294.1 - 2e-24 85.4 0.1 5.1e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFP12294.1 - 1.9e-15 57.0 0.2 6.1e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFP12294.1 - 1.2e-07 31.6 0.0 5.1e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFP12294.1 - 0.0019 18.3 0.1 0.0039 17.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFP12294.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 KFP12294.1 - 0.13 11.7 0.0 0.46 9.9 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Latexin PF06907.12 KFP12295.1 - 2.9e-70 236.1 1.6 3.2e-70 236.0 1.6 1.0 1 0 0 1 1 1 1 Latexin Latexin PF06907.12 KFP12296.1 - 7e-72 241.4 0.1 7.9e-72 241.3 0.1 1.0 1 0 0 1 1 1 1 Latexin MFS_1 PF07690.16 KFP12297.1 - 6.6e-41 140.4 67.1 2.2e-29 102.5 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP12297.1 - 5.7e-07 28.4 19.7 5.7e-07 28.4 19.7 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein IQCJ-SCHIP1 PF15157.6 KFP12298.1 - 3.6e-56 189.2 3.0 4.1e-56 189.1 3.0 1.0 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif CENP-Q PF13094.6 KFP12298.1 - 0.0011 19.1 0.7 0.0014 18.8 0.7 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IQ PF00612.27 KFP12298.1 - 0.0073 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Plasmid_RAQPRD PF09686.10 KFP12298.1 - 0.04 14.1 1.2 0.054 13.7 1.2 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SCHIP-1 PF10148.9 KFP12299.1 - 1.2e-89 299.9 13.3 1.4e-89 299.8 13.3 1.0 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 FEZ PF07763.13 KFP12299.1 - 0.00022 21.0 9.3 0.00039 20.2 9.3 1.5 1 1 0 1 1 1 1 FEZ-like protein DUF5102 PF17104.5 KFP12299.1 - 0.0091 16.1 6.8 0.012 15.6 6.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) EURL PF06937.11 KFP12299.1 - 0.16 11.4 7.0 0.2 11.0 1.6 2.0 1 1 0 2 2 2 0 EURL protein ABC_tran_Xtn PF12848.7 KFP12299.1 - 5 7.2 7.4 2.1 8.4 3.8 1.9 2 0 0 2 2 2 0 ABC transporter FIIND PF13553.6 KFP12300.1 - 1.1e-26 93.8 0.0 1.2e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Function to find SMC_N PF02463.19 KFP12303.1 - 3.7e-71 239.1 29.0 2e-70 236.7 29.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFP12303.1 - 1.7e-19 70.2 2.0 3.7e-19 69.2 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFP12303.1 - 2.1e-11 44.2 5.7 3.7e-05 23.7 0.0 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFP12303.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KFP12303.1 - 0.0014 18.4 50.3 0.0014 18.4 50.3 4.6 2 2 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFP12303.1 - 0.44 11.1 0.0 0.44 11.1 0.0 6.1 3 2 1 4 4 4 0 ABC transporter Vac_Fusion PF02346.16 KFP12303.1 - 2.1 8.0 17.2 0.2 11.3 0.1 5.2 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 zf-RING_UBOX PF13445.6 KFP12304.1 - 5.5e-11 42.3 6.1 5.5e-11 42.3 6.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.24 KFP12304.1 - 2.7e-08 33.8 1.3 2.7e-08 33.8 1.3 3.3 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4_2 PF13923.6 KFP12304.1 - 1e-07 31.7 1.9 1e-07 31.7 1.9 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP12304.1 - 1.2e-07 31.4 6.1 1.2e-07 31.4 6.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP12304.1 - 6.9e-07 29.5 7.5 6.9e-07 29.5 7.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP12304.1 - 1.8e-06 28.0 5.3 1.8e-06 28.0 5.3 3.0 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP12304.1 - 4.7e-06 26.5 4.9 4.7e-06 26.5 4.9 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP12304.1 - 7.3e-06 25.7 5.9 7.3e-06 25.7 5.9 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP12304.1 - 0.00019 21.2 4.7 0.00019 21.2 4.7 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 KFP12304.1 - 0.0028 17.8 0.1 0.032 14.4 0.1 2.4 1 1 0 1 1 1 1 U-box domain zf-RING_6 PF14835.6 KFP12304.1 - 0.013 15.4 2.1 0.013 15.4 2.1 2.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein LuxT_C PF18285.1 KFP12304.1 - 0.033 14.7 0.1 0.084 13.4 0.1 1.7 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain DUF349 PF03993.12 KFP12304.1 - 0.069 13.4 2.7 0.1 12.9 1.5 2.0 2 0 0 2 2 1 0 Domain of Unknown Function (DUF349) DUF1633 PF07794.11 KFP12304.1 - 0.096 10.8 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DASH_Dad3 PF08656.10 KFP12304.1 - 0.2 11.8 2.8 0.13 12.4 0.6 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 zf-RING_4 PF14570.6 KFP12304.1 - 0.24 11.2 4.5 1.3 8.8 4.5 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain HalX PF08663.10 KFP12304.1 - 0.35 11.2 1.7 0.75 10.2 1.7 1.5 1 0 0 1 1 1 0 HalX domain zinc_ribbon_12 PF11331.8 KFP12304.1 - 0.49 10.2 8.6 1.1 9.1 0.3 3.4 3 0 0 3 3 3 0 Probable zinc-ribbon domain DZR PF12773.7 KFP12304.1 - 1.5 8.9 6.5 0.23 11.5 0.5 2.6 3 1 0 3 3 3 0 Double zinc ribbon zf-RING_11 PF17123.5 KFP12304.1 - 2 8.3 13.1 0.065 13.0 5.7 2.5 2 0 0 2 2 2 0 RING-like zinc finger Arm PF00514.23 KFP12305.1 - 1.1e-91 298.4 19.0 2.9e-13 49.3 0.2 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFP12305.1 - 3.4e-25 87.3 3.1 2.6e-23 81.3 3.2 2.5 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFP12305.1 - 4.3e-22 78.2 1.8 4.5e-09 36.6 0.1 6.0 5 1 1 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 KFP12305.1 - 1.7e-19 70.0 0.6 2.8e-06 27.6 0.0 6.7 2 2 6 9 9 9 5 HEAT repeats HEAT PF02985.22 KFP12305.1 - 1.1e-17 62.6 5.1 0.0034 17.5 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat IBB PF01749.20 KFP12305.1 - 2.6e-16 59.8 2.6 7.2e-16 58.4 2.6 1.8 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.20 KFP12305.1 - 7.8e-08 31.3 1.9 5.6e-07 28.5 1.9 2.2 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFP12305.1 - 3.8e-07 30.2 1.0 0.1 12.7 0.1 4.4 4 1 1 5 5 5 3 V-ATPase subunit H Cnd1 PF12717.7 KFP12305.1 - 2.1e-06 27.9 1.6 0.07 13.2 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFP12305.1 - 1.1e-05 24.9 1.4 0.00065 19.1 0.5 2.6 1 1 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 KFP12305.1 - 8.6e-05 22.1 1.2 0.16 11.4 0.3 3.5 2 1 2 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 KFP12305.1 - 0.00038 20.4 1.2 0.55 10.3 0.0 4.8 3 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DRIM PF07539.12 KFP12305.1 - 0.0048 15.3 0.8 0.78 8.0 0.1 2.4 1 1 1 2 2 2 2 Down-regulated in metastasis RasGEF_N_2 PF14663.6 KFP12305.1 - 0.011 16.1 0.5 14 6.1 0.0 3.9 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 KFP12305.1 - 0.046 13.1 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Mo25-like CTNNBL PF08216.11 KFP12305.1 - 0.093 12.9 4.3 6.9 6.9 0.1 3.9 4 1 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear MMS19_N PF14500.6 KFP12305.1 - 0.13 11.9 0.0 0.9 9.1 0.0 2.2 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF4042 PF13251.6 KFP12305.1 - 0.29 10.8 1.8 2.3 7.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) PP2C PF00481.21 KFP12306.1 - 1.1e-57 195.6 0.0 1.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP12306.1 - 6.3e-08 32.5 0.0 2.4e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFP12306.1 - 0.0021 18.0 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) SPT_ssu-like PF11779.8 KFP12307.1 - 1.5e-16 59.8 9.0 1.9e-16 59.4 9.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like NMD3 PF04981.13 KFP12308.1 - 1.4e-80 270.2 6.6 2.1e-80 269.7 6.6 1.2 1 0 0 1 1 1 1 NMD3 family TMEM37 PF15108.6 KFP12308.1 - 0.016 15.1 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF1289 PF06945.13 KFP12308.1 - 0.2 11.5 3.2 6.1 6.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DZR PF12773.7 KFP12308.1 - 2.1 8.4 12.1 50 4.0 12.1 2.9 1 1 0 1 1 1 0 Double zinc ribbon RVT_1 PF00078.27 KFP12314.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PX PF00787.24 KFP12321.1 - 2.7e-19 69.2 1.0 3.8e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF641 PF04859.12 KFP12321.1 - 0.001 19.4 1.0 0.0072 16.7 0.6 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF4600 PF15372.6 KFP12321.1 - 0.091 13.2 3.3 0.23 11.9 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) LRRFIP PF09738.9 KFP12321.1 - 2.9 7.3 10.4 0.025 14.1 2.0 1.8 2 0 0 2 2 2 0 LRRFIP family DUF1635 PF07795.11 KFP12321.1 - 7.2 6.4 13.3 0.14 12.0 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Snf7 PF03357.21 KFP12322.1 - 3e-43 147.4 10.5 4.4e-43 146.9 10.5 1.2 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.12 KFP12322.1 - 0.0011 19.3 3.4 0.0014 19.0 2.8 1.4 1 1 0 1 1 1 1 SYF2 splicing factor DDE_Tnp_ISAZ013 PF07592.11 KFP12322.1 - 0.038 13.0 0.9 0.05 12.6 0.9 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain ABC_tran_CTD PF16326.5 KFP12322.1 - 0.12 12.6 10.7 2.7 8.3 0.4 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Enkurin PF13864.6 KFP12322.1 - 7.1 7.1 10.0 0.99 9.9 0.2 3.2 1 1 1 2 2 2 0 Calmodulin-binding zf-AN1 PF01428.16 KFP12323.1 - 1.2e-21 76.5 26.0 7.6e-13 48.4 12.4 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger EndoU_bacteria PF14436.6 KFP12323.1 - 0.079 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial EndoU nuclease Transp_Tc5_C PF04236.15 KFP12323.1 - 3.8 7.9 12.6 0.26 11.7 3.9 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.21 KFP12323.1 - 8.3 6.7 17.4 14 6.0 10.2 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Inositol_P PF00459.25 KFP12324.1 - 4.7e-87 292.0 0.1 5.7e-87 291.7 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Lipocalin PF00061.23 KFP12325.1 - 2.2e-26 92.8 4.5 2.4e-26 92.7 4.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP12325.1 - 0.00043 20.2 2.9 0.00055 19.9 2.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SCVP PF17619.2 KFP12325.1 - 0.033 15.0 3.1 1.1 10.2 3.0 2.7 2 1 0 2 2 2 0 Secreted clade V proteins Lipocalin PF00061.23 KFP12326.1 - 2.3e-24 86.2 1.1 2.6e-24 86.1 1.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP12326.1 - 9.1e-06 25.6 1.4 1.4e-05 25.1 1.4 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family SCVP PF17619.2 KFP12326.1 - 0.018 15.9 0.4 0.16 12.8 0.5 2.3 2 1 0 2 2 2 0 Secreted clade V proteins Lipocalin PF00061.23 KFP12327.1 - 3.9e-16 59.5 1.5 4.3e-16 59.4 1.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PhnA PF03831.14 KFP12327.1 - 0.019 14.8 0.8 0.13 12.2 0.1 2.1 1 1 0 2 2 2 0 PhnA domain MRP_L53 PF10780.9 KFP12328.1 - 1.1e-17 64.0 0.0 1.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 zf-C2H2 PF00096.26 KFP12330.1 - 0.0085 16.5 0.6 0.02 15.3 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type TPD52 PF04201.15 KFP12332.1 - 9e-76 253.0 7.9 1e-75 252.8 7.9 1.0 1 0 0 1 1 1 1 Tumour protein D52 family PEP-utilisers_N PF05524.13 KFP12332.1 - 0.0031 17.7 2.1 0.0053 16.9 2.1 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Occludin_ELL PF07303.13 KFP12332.1 - 0.0031 18.2 2.9 0.2 12.4 0.2 2.3 1 1 1 2 2 2 1 Occludin homology domain Cob_adeno_trans PF01923.18 KFP12332.1 - 0.015 15.5 2.9 0.022 14.9 2.7 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Uds1 PF15456.6 KFP12332.1 - 0.016 15.4 9.8 0.032 14.4 9.9 1.6 1 1 0 1 1 1 0 Up-regulated During Septation WXG100 PF06013.12 KFP12332.1 - 0.017 15.3 5.8 0.52 10.6 0.4 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG CHGN PF05679.16 KFP12332.1 - 0.051 12.4 1.0 0.061 12.1 1.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase AAA_13 PF13166.6 KFP12332.1 - 0.056 12.1 8.6 0.28 9.8 8.6 1.7 1 1 0 1 1 1 0 AAA domain HsbA PF12296.8 KFP12332.1 - 0.072 13.5 7.3 0.32 11.4 0.8 2.6 1 1 2 3 3 3 0 Hydrophobic surface binding protein A Atg14 PF10186.9 KFP12332.1 - 0.077 12.1 4.5 0.1 11.7 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 KFP12332.1 - 0.13 12.6 4.9 8 6.8 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein GvpK PF05121.12 KFP12332.1 - 0.13 12.3 2.6 1.7 8.8 3.3 2.3 2 1 1 3 3 3 0 Gas vesicle protein K Wx5_PLAF3D7 PF09688.10 KFP12332.1 - 0.14 12.2 5.3 0.11 12.5 3.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) SlyX PF04102.12 KFP12332.1 - 0.15 12.7 4.7 7.9 7.2 6.6 2.7 2 1 0 2 2 1 0 SlyX OmpH PF03938.14 KFP12332.1 - 0.26 11.6 9.9 0.35 11.2 8.6 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ada3 PF10198.9 KFP12332.1 - 0.31 11.2 4.9 0.33 11.1 4.9 1.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 TBCC_N PF16752.5 KFP12332.1 - 0.35 11.3 7.8 0.069 13.6 2.4 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF4795 PF16043.5 KFP12332.1 - 0.42 10.2 7.4 0.75 9.4 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 KFP12332.1 - 0.44 10.6 15.6 0.12 12.3 7.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 KFP12332.1 - 0.6 10.3 11.0 0.14 12.3 5.8 2.5 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 TMPIT PF07851.13 KFP12332.1 - 0.62 9.3 6.0 0.86 8.8 6.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 KFP12332.1 - 0.82 10.1 5.1 8.6 6.8 1.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 KFP12332.1 - 0.91 9.6 6.5 1.8 8.7 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) End3 PF12761.7 KFP12332.1 - 2.2 8.4 9.6 0.57 10.3 2.3 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 KFP12332.1 - 3.9 8.1 8.3 7.5 7.2 5.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 KFP12332.1 - 4.9 7.2 13.7 4 7.4 8.6 2.6 1 1 1 2 2 2 0 Prefoldin subunit MRP-S35 PF10246.9 KFP12333.1 - 5.4e-54 180.6 0.1 6.2e-54 180.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.23 KFP12333.1 - 0.051 13.9 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain HLH PF00010.26 KFP12335.1 - 3.5e-17 62.1 1.1 5.5e-17 61.5 1.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP12335.1 - 1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.11 KFP12335.1 - 0.046 12.9 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 Cache domain Stathmin PF00836.19 KFP12336.1 - 5e-57 191.7 24.9 6.3e-57 191.3 24.9 1.1 1 0 0 1 1 1 1 Stathmin family CCDC84 PF14968.6 KFP12336.1 - 0.054 13.1 4.4 0.054 13.1 4.4 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 FmdE PF02663.14 KFP12336.1 - 0.37 10.8 6.4 2.2 8.3 6.4 2.0 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Type2_restr_D3 PF16902.5 KFP12336.1 - 1.5 8.8 4.9 9.5 6.2 0.2 2.5 1 1 0 2 2 2 0 Type-2 restriction enzyme D3 domain Exonuc_VII_L PF02601.15 KFP12336.1 - 3.2 7.2 10.3 3.7 7.0 10.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2HC_2 PF13913.6 KFP12339.1 - 5.2e-14 51.7 7.0 1.3e-08 34.6 0.7 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFP12339.1 - 0.0025 17.9 0.8 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 KIAA1045 RING finger DZR PF12773.7 KFP12339.1 - 0.025 14.6 12.0 0.094 12.8 2.6 3.1 3 0 0 3 3 3 0 Double zinc ribbon TRAF6_Z2 PF18048.1 KFP12339.1 - 0.11 12.6 2.0 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2 PF00096.26 KFP12339.1 - 0.28 11.7 14.8 0.74 10.4 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2321 PF10083.9 KFP12339.1 - 0.84 9.3 3.0 3.5 7.3 3.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_4 PF13894.6 KFP12339.1 - 1.3 10.0 0.1 0.55 11.2 0.6 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger HypA PF01155.19 KFP12339.1 - 1.7 8.7 9.0 4.3 7.4 1.8 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rod_cone_degen PF15201.6 KFP12339.1 - 2 8.6 4.6 0.68 10.1 1.1 2.0 2 0 0 2 2 2 0 Progressive rod-cone degeneration UL42 PF17638.2 KFP12339.1 - 5.7 6.9 9.2 0.25 11.3 0.9 2.7 4 0 0 4 4 4 0 HCMV UL42 PKI PF02827.16 KFP12340.1 - 1.2e-29 102.3 0.3 1.4e-29 102.1 0.3 1.1 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Yae1_N PF09811.9 KFP12342.1 - 6.5e-13 48.1 48.4 1.8e+04 -13.3 48.4 4.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RVT_1 PF00078.27 KFP12344.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pex2_Pex12 PF04757.14 KFP12348.1 - 6.6e-39 133.8 6.4 8.7e-39 133.4 6.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 KFP12348.1 - 5.1e-08 32.7 8.8 5.1e-08 32.7 8.8 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP12348.1 - 0.00034 20.4 5.9 0.00072 19.4 5.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP12348.1 - 0.00066 19.7 7.6 0.00066 19.7 7.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP12348.1 - 0.0016 18.2 9.1 0.0034 17.2 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP12348.1 - 0.0017 18.1 9.4 0.0017 18.1 9.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP12348.1 - 0.0044 17.2 11.9 0.013 15.6 11.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP12348.1 - 0.015 15.2 11.8 0.015 15.2 11.8 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFP12348.1 - 0.039 14.3 8.6 0.039 14.3 8.6 2.1 2 0 0 2 2 2 0 Ring finger domain RDD PF06271.12 KFP12348.1 - 0.056 13.6 0.8 0.27 11.4 0.4 1.9 1 1 1 2 2 2 0 RDD family zinc-ribbons_6 PF07191.12 KFP12348.1 - 3.9 7.5 11.4 0.22 11.5 5.6 1.8 2 0 0 2 2 2 0 zinc-ribbons Homeodomain PF00046.29 KFP12350.1 - 1.3e-68 226.7 20.5 4.2e-18 64.9 0.4 5.1 4 0 0 4 4 4 4 Homeodomain zf-C2H2_4 PF13894.6 KFP12350.1 - 1.2e-15 56.8 135.0 0.13 13.2 0.4 22.9 23 0 0 23 23 23 11 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP12350.1 - 4.4e-14 52.1 152.4 0.0027 18.0 0.2 22.8 24 0 0 24 24 24 11 Zinc finger, C2H2 type Homeobox_KN PF05920.11 KFP12350.1 - 2.1e-13 49.9 3.1 0.023 14.6 0.1 4.9 4 0 0 4 4 4 4 Homeobox KN domain zf-met PF12874.7 KFP12350.1 - 1.4e-08 34.8 103.4 0.00038 20.8 0.9 16.4 17 0 0 17 17 17 8 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP12350.1 - 5.3e-06 26.1 82.4 0.0005 19.8 0.8 11.8 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFP12350.1 - 0.00048 20.4 8.2 0.00048 20.4 8.2 11.6 12 2 0 12 12 11 4 Drought induced 19 protein (Di19), zinc-binding MerR_1 PF13411.6 KFP12350.1 - 0.0026 17.8 0.2 0.047 13.8 0.0 3.1 3 0 0 3 3 3 1 MerR HTH family regulatory protein zf-C2H2_6 PF13912.6 KFP12350.1 - 0.0061 16.5 0.3 0.0061 16.5 0.3 13.9 17 0 0 17 17 17 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP12350.1 - 0.0077 16.6 127.5 1.1 9.7 2.6 20.4 16 6 5 21 21 21 5 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFP12350.1 - 0.24 11.7 115.4 0.15 12.4 0.2 18.1 19 0 0 19 19 19 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFP12350.1 - 0.47 10.3 23.2 14 5.6 1.4 6.5 6 0 0 6 6 6 0 GAGA factor RVT_1 PF00078.27 KFP12351.1 - 3e-12 46.6 0.0 4.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP12351.1 - 0.003 17.6 0.0 0.012 15.6 0.0 2.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Arg_repressor PF01316.21 KFP12351.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Hormone_recep PF00104.30 KFP12353.1 - 2.8e-42 144.6 0.1 4.8e-42 143.9 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP12353.1 - 2.1e-27 95.4 17.9 3.9e-27 94.5 17.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RVT_1 PF00078.27 KFP12354.1 - 0.002 17.7 0.0 0.004 16.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LCCL PF03815.19 KFP12356.1 - 6.4e-51 170.4 16.8 1e-26 92.9 0.7 3.2 3 0 0 3 3 3 2 LCCL domain CAP PF00188.26 KFP12356.1 - 3.5e-20 73.1 1.4 3.5e-20 73.1 1.4 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Rxt3 PF08642.10 KFP12356.1 - 0.0017 19.2 1.8 0.057 14.2 0.0 3.1 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 DUF2889 PF11136.8 KFP12356.1 - 0.064 13.6 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) CAP PF00188.26 KFP12357.1 - 2.6e-25 89.7 2.2 3.8e-25 89.2 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GST_N_3 PF13417.6 KFP12359.1 - 3.9e-11 43.2 0.0 8.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFP12359.1 - 2.2e-10 40.7 0.1 5.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP12359.1 - 2.4e-09 37.1 0.0 4.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP12359.1 - 1.8e-08 34.5 0.1 5e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP12359.1 - 3.2e-08 33.7 0.0 8.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP12359.1 - 5.2e-07 29.8 0.0 2.7e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP12359.1 - 0.0022 18.3 0.0 0.0061 16.9 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KFP12359.1 - 0.024 15.4 0.0 0.049 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF3206 PF11472.8 KFP12359.1 - 0.03 14.3 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF1617 PF07761.12 KFP12359.1 - 0.032 14.3 0.9 0.057 13.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Fmp27_WPPW PF10359.9 KFP12359.1 - 0.049 12.5 0.1 0.067 12.0 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MCR_C PF04609.12 KFP12359.1 - 0.12 11.4 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C CCDC-167 PF15188.6 KFP12359.1 - 5.7 7.3 7.7 13 6.2 0.2 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 TMEM70 PF06979.12 KFP12361.1 - 1.5e-57 193.7 8.9 1.8e-57 193.4 8.9 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Skp1_POZ PF03931.15 KFP12362.1 - 3.1e-11 43.3 0.0 4.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PTAC PF06130.12 KFP12362.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphate propanoyltransferase UQ_con PF00179.26 KFP12363.1 - 8.4e-34 116.2 0.2 9.1e-34 116.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFP12363.1 - 0.015 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain Prok-E2_A PF14457.6 KFP12363.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A dsrm PF00035.26 KFP12365.1 - 2.7e-50 169.0 2.6 2.6e-13 50.5 0.1 4.8 4 0 0 4 4 4 4 Double-stranded RNA binding motif Staufen_C PF16482.5 KFP12365.1 - 1.1e-20 73.8 0.4 2.9e-16 59.6 0.3 5.2 5 1 0 5 5 5 1 Staufen C-terminal domain DND1_DSRM PF14709.7 KFP12365.1 - 2.2e-07 31.0 5.2 0.16 12.3 0.1 5.3 4 2 0 4 4 4 2 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 KFP12365.1 - 0.014 15.6 1.7 55 4.0 0.0 4.4 4 0 0 4 4 4 0 Dicer dimerisation domain Ribosomal_L30_N PF08079.12 KFP12367.1 - 1.3e-27 95.8 16.2 2.5e-27 94.9 16.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFP12367.1 - 1.6e-25 88.8 1.2 4.1e-25 87.4 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e TSP_1 PF00090.19 KFP12368.1 - 1.8e-06 28.1 2.4 1.8e-06 28.1 2.4 2.7 2 1 1 3 3 3 1 Thrombospondin type 1 domain TRF PF08558.10 KFP12369.1 - 6.5e-25 88.1 3.3 1.1e-24 87.4 3.3 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFP12369.1 - 7.7e-09 35.6 0.4 7.7e-09 35.6 0.4 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP12369.1 - 0.0011 19.2 0.5 0.0023 18.2 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_14 PF13428.6 KFP12369.1 - 0.025 15.4 0.0 0.068 14.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP12369.1 - 0.046 13.7 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 KFP12370.1 - 2.9e-95 313.0 32.8 9.9e-13 48.5 0.0 8.0 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP12370.1 - 1.6e-59 197.5 14.8 1.8e-08 34.8 0.0 10.6 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KFP12370.1 - 1.4e-57 189.7 18.0 1.1e-06 28.8 0.0 14.6 13 1 1 14 14 14 13 Ankyrin repeat Ank_3 PF13606.6 KFP12370.1 - 2.7e-57 184.0 15.9 0.00017 21.7 0.0 15.9 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 KFP12370.1 - 5e-50 166.9 12.2 8.7e-07 29.1 0.0 12.0 3 3 8 12 12 12 10 Ankyrin repeats (many copies) Ion_trans PF00520.31 KFP12370.1 - 1e-15 57.6 18.7 1.6e-15 57.0 18.7 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFP12370.1 - 2.7e-05 23.0 18.6 0.0027 16.4 12.1 2.3 1 1 1 2 2 2 2 Polycystin cation channel SchA_CurD PF04486.12 KFP12370.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 SchA/CurD like domain GON PF08685.11 KFP12372.1 - 0.22 11.4 0.0 0.23 11.3 0.0 1.0 1 0 0 1 1 1 0 GON domain XK-related PF09815.9 KFP12374.1 - 2.7e-92 309.5 28.8 3.1e-92 309.3 28.8 1.0 1 0 0 1 1 1 1 XK-related protein TRAM_LAG1_CLN8 PF03798.16 KFP12375.1 - 3.6e-26 92.1 18.8 3.6e-26 92.1 18.8 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFP12375.1 - 2.1e-22 78.5 2.6 2.6e-22 78.3 0.7 2.2 2 0 0 2 2 2 1 TRAM1-like protein DUF3382 PF11862.8 KFP12375.1 - 0.036 14.3 0.1 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3671 PF12420.8 KFP12375.1 - 1.3 9.1 10.5 0.17 12.0 3.5 2.8 2 1 1 3 3 3 0 Protein of unknown function zf-H2C2_2 PF13465.6 KFP12377.1 - 7.9e-22 76.7 53.4 2.6e-09 37.1 0.7 6.7 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP12377.1 - 2.3e-19 68.7 56.6 3.2e-07 30.4 3.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP12377.1 - 7.4e-18 63.7 53.7 0.00013 22.5 3.1 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP12377.1 - 5.9e-09 36.0 31.2 0.0035 17.6 0.6 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP12377.1 - 3.2e-06 27.0 41.9 0.00023 21.0 3.5 6.9 7 1 0 7 7 6 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP12377.1 - 4.8e-05 23.1 29.0 0.065 13.2 2.8 6.4 6 0 0 6 6 6 3 zinc-finger of a C2HC-type SET PF00856.28 KFP12377.1 - 8.7e-05 23.0 0.1 0.0036 17.7 0.1 2.4 1 1 0 1 1 1 1 SET domain zf-met PF12874.7 KFP12377.1 - 0.00072 19.9 33.4 0.28 11.6 2.5 6.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFP12377.1 - 0.0022 18.7 21.9 0.082 13.7 1.4 3.7 1 1 2 3 3 3 2 zinc-ribbon family zf_UBZ PF18439.1 KFP12377.1 - 0.0033 17.0 28.2 0.69 9.6 0.2 6.5 6 1 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KFP12377.1 - 0.0068 16.1 2.8 0.0068 16.1 2.8 6.3 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP12377.1 - 0.019 15.3 35.4 0.46 10.8 2.2 5.7 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KFP12377.1 - 0.025 14.9 34.2 0.31 11.4 5.5 3.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding YhfH PF14149.6 KFP12377.1 - 0.027 14.4 12.1 6.5 6.8 1.1 4.6 4 0 0 4 4 4 0 YhfH-like protein Zn-ribbon_8 PF09723.10 KFP12377.1 - 0.068 13.3 25.3 0.86 9.8 1.5 4.9 3 2 2 5 5 5 0 Zinc ribbon domain PyrI_C PF02748.15 KFP12377.1 - 0.19 11.7 24.8 0.29 11.1 0.2 5.9 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HypA PF01155.19 KFP12377.1 - 0.9 9.6 19.2 5 7.2 3.2 3.7 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Sec23_Sec24 PF04810.15 KFP12377.1 - 1.8 8.6 17.7 34 4.6 0.4 5.4 4 2 1 5 5 5 0 Sec23/Sec24 zinc finger LIM PF00412.22 KFP12377.1 - 2.1 8.6 26.4 8.2 6.7 2.7 4.8 2 1 2 4 4 4 0 LIM domain HNH_5 PF14279.6 KFP12377.1 - 2.2 8.2 20.7 5.4 7.0 0.1 5.4 5 1 0 5 5 5 0 HNH endonuclease zf-BED PF02892.15 KFP12377.1 - 4.1 7.5 39.2 1.1 9.3 0.5 6.2 1 1 4 6 6 6 0 BED zinc finger DUF2256 PF10013.9 KFP12377.1 - 4.3 7.5 21.9 12 6.1 0.1 6.1 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-AN1 PF01428.16 KFP12377.1 - 5.8 7.2 34.8 3.3 8.0 2.5 6.7 6 0 0 6 6 6 0 AN1-like Zinc finger zf-CHCC PF10276.9 KFP12377.1 - 7.3 6.7 16.8 8.4 6.5 0.0 5.1 5 0 0 5 5 5 0 Zinc-finger domain DUF3740 PF12548.8 KFP12379.1 - 5.2e-61 205.4 13.0 1.9e-53 180.9 1.5 2.6 2 0 0 2 2 2 2 Sulfatase protein Sulfatase PF00884.23 KFP12379.1 - 3.9e-47 161.2 2.2 4e-47 161.1 0.7 1.8 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFP12379.1 - 0.053 13.1 1.6 0.33 10.5 0.2 2.7 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5586 PF17824.1 KFP12383.1 - 1.4e-196 653.4 13.2 1.6e-196 653.3 13.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5586) DEAD_assoc PF08494.11 KFP12383.1 - 0.094 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 DEAD/H associated DEP PF00610.21 KFP12385.1 - 3.2e-40 136.0 0.1 1.6e-22 79.3 0.0 3.1 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.20 KFP12385.1 - 1.3e-37 129.8 2.0 1.3e-37 129.8 2.0 2.2 2 0 0 2 2 2 1 RhoGEF domain PDZ_6 PF17820.1 KFP12385.1 - 3e-12 46.2 0.1 1.5e-05 24.7 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFP12385.1 - 7.6e-11 42.2 0.1 7.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP12385.1 - 5.5e-05 23.4 0.0 0.46 10.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 KFP12385.1 - 0.0015 19.0 0.5 0.007 16.9 0.5 2.2 1 0 0 1 1 1 1 PH domain Lge1 PF11488.8 KFP12385.1 - 6.2 7.1 7.2 11 6.3 0.3 3.6 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Peptidase_M14 PF00246.24 KFP12387.1 - 1.2e-88 297.7 0.1 1.4e-88 297.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP12387.1 - 6.6e-11 42.4 0.1 1.5e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Sec7 PF01369.20 KFP12388.1 - 2.4e-75 252.2 0.6 6.8e-75 250.8 0.6 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFP12388.1 - 1.6e-49 167.9 3.4 1.6e-49 167.9 3.4 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFP12388.1 - 8e-40 136.4 0.1 8e-40 136.4 0.1 3.5 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFP12388.1 - 8.3e-36 121.7 0.2 8.3e-36 121.7 0.2 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Sec23_helical PF04815.15 KFP12388.1 - 0.36 10.7 1.8 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Sec23/Sec24 helical domain JAB PF01398.21 KFP12389.1 - 4.1e-34 117.1 0.0 6.4e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFP12389.1 - 1.5e-24 86.7 0.6 2.4e-24 86.1 0.6 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFP12389.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFP12389.1 - 0.0034 17.4 0.1 0.007 16.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.7 KFP12390.1 - 1.3e-22 79.5 27.2 9.1e-08 32.3 3.2 5.2 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP12390.1 - 1.3e-18 67.1 16.8 8.1e-10 38.5 1.7 2.7 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 KFP12390.1 - 1.4e-15 56.8 21.2 4.4e-06 26.4 1.5 5.3 3 1 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 KFP12390.1 - 5.1e-10 38.5 22.1 0.33 11.7 0.0 7.3 6 1 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 KFP12390.1 - 0.00011 22.0 18.2 2.9 8.2 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat FNIP PF05725.12 KFP12390.1 - 0.4 10.9 5.9 1.4 9.1 1.8 3.5 2 1 0 2 2 2 0 FNIP Repeat HLH PF00010.26 KFP12392.1 - 2.5e-13 49.8 0.0 3.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5437 PF17505.2 KFP12392.1 - 0.23 11.5 1.3 1.3 9.1 1.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5437) MCM_lid PF17855.1 KFP12393.1 - 5e-11 42.9 0.3 9.4e-11 42.0 0.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 KFP12393.1 - 4e-05 22.8 0.0 8.2e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain Pkinase PF00069.25 KFP12394.1 - 7.2e-68 228.8 0.0 8.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12394.1 - 8.7e-35 120.2 0.0 1e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP12394.1 - 2.2e-05 23.9 0.0 7.9e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KFP12394.1 - 0.00025 21.7 0.1 0.0005 20.7 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KFP12394.1 - 0.0011 18.6 0.1 0.21 11.2 0.1 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP12394.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP12394.1 - 0.068 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain 7tm_1 PF00001.21 KFP12395.1 - 7.1e-53 179.6 22.4 9.5e-53 179.2 22.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12395.1 - 1.7e-15 57.1 21.7 2.1e-15 56.8 21.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP12395.1 - 7.9e-05 22.5 18.2 0.00012 21.9 18.2 1.3 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12396.1 - 1.3e-52 178.7 27.4 7.2e-52 176.3 28.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12396.1 - 1.9e-14 53.7 26.6 2.4e-14 53.3 26.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP12396.1 - 0.00034 20.4 15.3 0.00041 20.2 14.5 1.6 1 1 0 1 1 1 1 Olfactory receptor Cu-oxidase_2 PF07731.14 KFP12397.1 - 2.4e-31 108.3 15.6 1.7e-13 50.5 1.9 6.4 6 1 0 6 6 6 5 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFP12397.1 - 1.4e-26 92.9 1.6 4.7e-08 33.1 0.0 5.4 5 0 0 5 5 5 3 Multicopper oxidase RhoGAP PF00620.27 KFP12398.1 - 1.5e-35 122.3 0.0 8.9e-35 119.8 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 KFP12398.1 - 3e-06 27.8 0.0 7.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFP12398.1 - 1.2e-05 25.8 0.1 3.9e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 PH domain Ras_bdg_2 PF14847.6 KFP12398.1 - 0.00033 20.9 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 Ras-binding domain of Byr2 YhfZ_C PF14503.6 KFP12398.1 - 0.046 13.3 0.2 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 YhfZ C-terminal domain Fer2 PF00111.27 KFP12399.1 - 1.1e-07 31.7 0.7 1.6e-07 31.2 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zf_RING PF16744.5 KFP12399.1 - 0.038 14.1 0.3 0.27 11.4 0.4 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger DUF3856 PF12968.7 KFP12399.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) ERM PF00769.19 KFP12400.1 - 1.6e-72 244.3 73.4 1.6e-72 244.3 73.4 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFP12400.1 - 9.7e-28 96.4 0.0 3.6e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP12400.1 - 2e-27 95.9 0.4 2e-27 95.9 0.4 3.8 2 1 0 3 3 3 1 FERM central domain FERM_N PF09379.10 KFP12400.1 - 4e-15 55.5 0.4 6.3e-14 51.7 0.1 2.6 2 0 0 2 2 2 1 FERM N-terminal domain Las1 PF04031.13 KFP12401.1 - 5.8e-32 110.9 0.0 7.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Las1-like DnaB_C PF03796.15 KFP12401.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain LAX PF15681.5 KFP12402.1 - 0.053 12.3 0.3 0.069 12.0 0.3 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X RNase_Zc3h12a PF11977.8 KFP12403.1 - 4.7e-66 221.4 0.0 6.2e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP12403.1 - 3.6e-19 68.4 0.2 9e-19 67.1 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFP12403.1 - 7.5e-05 22.4 7.0 0.00018 21.3 7.0 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger PRORP PF16953.5 KFP12403.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P Omega-toxin PF06357.11 KFP12403.1 - 0.89 9.4 7.8 0.083 12.7 3.0 1.7 2 0 0 2 2 2 0 Omega-atracotoxin zf-CCCH_2 PF14608.6 KFP12403.1 - 1.1 9.9 9.6 2.6 8.6 9.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFP12403.1 - 1.1 9.3 8.3 9.3 6.3 8.3 2.2 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C4H2 PF10146.9 KFP12404.1 - 2.2e-76 256.9 19.9 2.4e-76 256.8 19.9 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 KFP12404.1 - 0.0062 16.5 0.8 0.011 15.7 0.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon Sec20 PF03908.13 KFP12404.1 - 0.0064 16.4 0.7 0.012 15.5 0.2 1.7 1 1 1 2 2 2 1 Sec20 DUF16 PF01519.16 KFP12404.1 - 0.017 15.6 2.1 0.026 15.0 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 Spc7 PF08317.11 KFP12404.1 - 0.052 12.4 12.6 0.064 12.1 12.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C3HC4_3 PF13920.6 KFP12404.1 - 0.06 13.2 4.2 0.1 12.5 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tup_N PF08581.10 KFP12404.1 - 0.068 13.5 8.9 0.24 11.7 8.1 2.1 1 1 1 2 2 2 0 Tup N-terminal zf-P11 PF03854.14 KFP12404.1 - 0.078 12.7 2.2 0.15 11.7 2.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF3365 PF11845.8 KFP12404.1 - 0.086 13.2 3.1 0.11 12.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) zf-RING_4 PF14570.6 KFP12404.1 - 0.1 12.4 2.7 0.2 11.5 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Fez1 PF06818.15 KFP12404.1 - 0.12 12.8 10.3 0.19 12.1 10.3 1.4 1 0 0 1 1 1 0 Fez1 BLOC1_2 PF10046.9 KFP12404.1 - 0.13 12.6 8.2 3.9 7.8 2.3 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KFP12404.1 - 0.29 10.4 12.3 1.4 8.2 7.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KFP12404.1 - 0.42 10.7 4.3 1 9.4 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KFP12404.1 - 1.3 7.5 5.7 2.1 6.8 5.6 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KFP12404.1 - 1.8 6.4 6.2 2 6.2 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 KFP12404.1 - 3.6 7.8 16.1 5 7.4 6.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding LMBR1 PF04791.16 KFP12404.1 - 3.9 6.3 3.8 4.3 6.1 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DASH_Dad1 PF08649.10 KFP12404.1 - 5.3 7.3 6.6 1.1 9.5 0.5 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 YabA PF06156.13 KFP12404.1 - 5.4 7.7 12.6 1 10.1 3.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 KFP12404.1 - 7.2 5.1 7.9 9.2 4.7 7.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KFP12404.1 - 8.1 5.9 9.3 8.2 5.9 8.8 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit PI31_Prot_N PF11566.8 KFP12405.1 - 1.4e-16 60.7 0.0 1.8e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KFP12405.1 - 6.7e-07 30.4 15.3 1.7e-06 29.1 15.3 1.8 1 1 0 1 1 1 1 PI31 proteasome regulator Rad21_Rec8_N PF04825.13 KFP12406.1 - 4.3e-38 129.9 0.3 2.2e-37 127.6 0.0 2.1 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein AIP3 PF03915.13 KFP12407.1 - 3.6e-12 46.1 11.4 2.2e-09 36.9 0.0 6.3 6 2 0 8 8 8 4 Actin interacting protein 3 Pribosyltran PF00156.27 KFP12408.1 - 9.2e-15 54.5 0.0 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Enkurin PF13864.6 KFP12409.1 - 2.5e-26 92.0 9.6 2.5e-26 92.0 9.6 2.3 3 0 0 3 3 3 1 Calmodulin-binding AAA_9 PF12781.7 KFP12409.1 - 0.025 13.7 0.1 0.046 12.8 0.1 1.4 1 0 0 1 1 1 0 ATP-binding dynein motor region SKI PF01202.22 KFP12410.1 - 1.5e-34 119.4 0.0 3e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.6 KFP12410.1 - 2.5e-14 53.2 0.0 6.7e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus AAA_18 PF13238.6 KFP12410.1 - 1.9e-07 31.7 0.0 6.8e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain PALP PF00291.25 KFP12410.1 - 1.3e-05 24.8 0.0 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 KFP12410.1 - 2.5e-05 24.7 0.0 0.00038 20.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFP12410.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KFP12410.1 - 0.0025 18.2 0.1 0.037 14.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KFP12410.1 - 0.0037 17.0 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP12410.1 - 0.0051 17.0 0.0 0.018 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP12410.1 - 0.012 15.9 0.1 0.042 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Acid_PPase PF12689.7 KFP12410.1 - 0.034 14.0 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 Acid Phosphatase Zeta_toxin PF06414.12 KFP12410.1 - 0.04 13.2 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Par3_HAL_N_term PF12053.8 KFP12410.1 - 0.044 14.0 0.1 0.79 10.0 0.0 2.8 3 0 0 3 3 2 0 N-terminal of Par3 and HAL proteins IstB_IS21 PF01695.17 KFP12410.1 - 0.046 13.5 0.2 0.31 10.8 0.1 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KFP12410.1 - 0.079 12.7 0.1 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 KFP12410.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 KFP12410.1 - 0.16 12.1 0.0 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase AAA_16 PF13191.6 KFP12410.1 - 0.18 12.1 0.0 1.6 9.1 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain 7tm_3 PF00003.22 KFP12411.1 - 5.4e-33 114.7 22.2 8.2e-33 114.1 22.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Myosin_head PF00063.21 KFP12412.1 - 1.1e-198 661.7 6.7 4.7e-198 659.6 6.7 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 KFP12412.1 - 5e-61 206.4 0.0 9.6e-61 205.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12412.1 - 8.4e-44 149.8 0.0 1.6e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 KFP12412.1 - 6.9e-24 81.4 21.0 1e-05 24.9 0.2 5.7 5 0 0 5 5 5 5 IQ calmodulin-binding motif Kinase-like PF14531.6 KFP12412.1 - 0.00042 19.7 0.3 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP12412.1 - 0.0011 19.0 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Hs1pro-1_N PF07231.12 KFP12412.1 - 0.035 13.9 1.6 0.039 13.7 0.1 1.8 2 0 0 2 2 2 0 Hs1pro-1 N-terminus AAA_22 PF13401.6 KFP12412.1 - 0.096 13.0 0.0 0.47 10.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Pyridoxal_deC PF00282.19 KFP12413.1 - 3.7e-136 453.7 0.0 4.4e-136 453.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFP12413.1 - 4.9e-05 22.4 0.0 0.0003 19.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP12413.1 - 0.00096 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TNFR_c6 PF00020.18 KFP12414.1 - 1.5e-06 28.5 10.1 3.2e-06 27.4 10.1 1.6 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region Aspzincin_M35 PF14521.6 KFP12414.1 - 0.082 13.5 1.1 0.1 13.2 1.1 1.2 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase RA PF00788.23 KFP12415.1 - 1.3e-12 48.1 1.8 3.9e-12 46.7 0.7 2.2 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFP12415.1 - 1.8e-12 47.7 0.2 4.8e-12 46.3 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP12415.1 - 0.002 18.5 0.2 0.0061 17.0 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain UPF0061 PF02696.14 KFP12416.1 - 1e-91 308.1 0.0 1.2e-91 307.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family polyprenyl_synt PF00348.17 KFP12417.1 - 7.6e-71 238.2 0.0 9.6e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFP12417.1 - 0.00096 18.8 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Abi_HHR PF07815.14 KFP12418.1 - 1.3e-34 118.2 0.4 2.7e-34 117.2 0.4 1.6 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 KFP12418.1 - 3.8e-09 36.0 0.6 6.4e-09 35.3 0.6 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP12418.1 - 3.8e-06 26.7 0.1 9.4e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain CNTF PF01110.17 KFP12418.1 - 0.013 14.8 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Ciliary neurotrophic factor SH3_2 PF07653.17 KFP12418.1 - 0.042 13.5 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain ACBP PF00887.19 KFP12419.1 - 3e-23 81.8 0.1 6.7e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Pkinase PF00069.25 KFP12420.1 - 2.7e-51 174.5 0.1 1.8e-30 106.2 0.9 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12420.1 - 1.2e-25 90.3 0.2 3.5e-18 65.8 1.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP12420.1 - 0.00061 18.8 0.1 0.0012 17.8 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP12420.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP12420.1 - 0.007 15.7 0.4 0.014 14.8 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP12420.1 - 0.0079 15.5 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFP12420.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Patched PF02460.18 KFP12421.1 - 1.5e-155 519.5 20.5 1.7e-155 519.3 20.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFP12421.1 - 1.8e-38 131.8 3.5 1.8e-38 131.8 3.5 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation zf-C2H2 PF00096.26 KFP12422.1 - 1e-14 54.1 41.0 0.00018 21.8 1.3 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP12422.1 - 1.2e-13 50.6 39.9 0.0035 18.0 0.8 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP12422.1 - 8.6e-08 32.3 46.1 0.00033 20.9 1.1 7.1 7 1 0 7 7 7 4 Zinc-finger double domain zf-AD PF07776.15 KFP12422.1 - 0.00031 20.9 0.4 0.00031 20.9 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger associated domain (zf-AD) Zn-ribbon_8 PF09723.10 KFP12422.1 - 0.00044 20.3 16.3 0.16 12.1 0.0 4.3 4 0 0 4 4 4 2 Zinc ribbon domain CpXC PF14353.6 KFP12422.1 - 0.00073 19.6 13.9 0.088 12.9 0.2 4.3 2 1 2 4 4 4 2 CpXC protein zf-C2H2_aberr PF17017.5 KFP12422.1 - 0.0097 16.1 2.5 0.0097 16.1 2.5 2.4 1 1 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFP12422.1 - 0.01 15.8 0.3 0.01 15.8 0.3 5.4 6 0 0 6 6 6 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFP12422.1 - 0.23 11.1 15.5 1.1 8.9 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_10 PF10058.9 KFP12422.1 - 1.2 9.0 9.0 1.6 8.5 0.0 3.8 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein YL1 PF05764.13 KFP12422.1 - 1.5 8.9 12.0 0.78 9.8 5.8 2.3 2 1 0 2 2 2 0 YL1 nuclear protein IBR PF01485.21 KFP12422.1 - 3.3 8.0 24.8 2.6 8.3 0.5 4.8 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain GAGA PF09237.11 KFP12422.1 - 4.4 7.2 8.0 6.7 6.6 0.4 3.7 3 2 1 4 4 3 0 GAGA factor RbpA PF13397.6 KFP12422.1 - 6.9 7.3 7.2 13 6.4 0.8 3.3 3 0 0 3 3 3 0 RNA polymerase-binding protein Snf7 PF03357.21 KFP12423.1 - 2.3e-11 43.6 15.6 2.9e-11 43.3 15.6 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KFP12423.1 - 0.06 13.0 0.4 0.1 12.3 0.4 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Wbp11 PF09429.10 KFP12423.1 - 0.49 10.8 0.1 0.49 10.8 0.1 2.8 2 1 1 3 3 3 0 WW domain binding protein 11 DUF1843 PF08898.10 KFP12423.1 - 0.54 10.8 5.5 1.9 9.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Enkurin PF13864.6 KFP12423.1 - 0.75 10.3 4.9 1.4 9.4 2.8 2.3 1 1 1 2 2 2 0 Calmodulin-binding Fes1 PF08609.10 KFP12423.1 - 1.4 9.8 7.3 0.69 10.8 2.7 2.5 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Sulfotransfer_1 PF00685.27 KFP12424.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.3 1 1 0 1 1 1 0 Sulfotransferase domain Ribosomal_L13e PF01294.18 KFP12425.1 - 2.6e-67 226.2 4.9 3.5e-67 225.7 4.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ank_2 PF12796.7 KFP12426.1 - 1.9e-18 66.8 0.2 2.7e-09 37.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP12426.1 - 6.8e-18 64.2 0.4 0.00016 21.9 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP12426.1 - 1.4e-17 63.5 0.3 3.4e-08 33.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP12426.1 - 2.7e-14 53.3 0.2 3.5e-06 27.5 0.1 3.2 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP12426.1 - 6.9e-14 50.6 0.1 0.00066 19.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat YcbB PF08664.10 KFP12427.1 - 0.021 14.9 1.8 0.021 14.9 1.8 2.8 4 0 0 4 4 4 0 YcbB domain IL32 PF15225.6 KFP12427.1 - 3 8.2 4.7 1 9.7 0.1 2.6 3 0 0 3 3 3 0 Interleukin 32 Longin PF13774.6 KFP12428.1 - 4.2e-16 58.8 0.1 7.1e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SCAMP PF04144.13 KFP12428.1 - 0.036 14.4 4.6 0.075 13.3 4.6 1.5 1 0 0 1 1 1 0 SCAMP family GDPD PF03009.17 KFP12430.1 - 6.8e-21 75.2 0.0 5.6e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KFP12430.1 - 0.11 13.0 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Ribosomal_S3_C PF00189.20 KFP12431.1 - 2.8e-23 82.2 0.1 1e-22 80.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFP12431.1 - 8.8e-12 44.7 0.1 1.4e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 KH domain SH3_1 PF00018.28 KFP12432.1 - 1e-25 89.1 1.4 2.5e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP12432.1 - 1.1e-24 86.0 1.8 2.5e-13 49.7 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP12432.1 - 3.4e-21 74.7 0.2 6.6e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KFP12432.1 - 0.00011 22.4 0.2 0.00011 22.4 0.2 3.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain hSH3 PF14603.6 KFP12432.1 - 0.0014 19.0 0.1 0.0078 16.6 0.0 2.3 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFP12432.1 - 0.003 17.8 0.5 0.0069 16.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain H-kinase_dim PF02895.14 KFP12432.1 - 0.12 12.7 2.6 6.3 7.3 0.1 3.4 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain OmpH PF03938.14 KFP12432.1 - 0.43 10.9 13.7 1.3 9.3 1.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cob_adeno_trans PF01923.18 KFP12432.1 - 1.2 9.2 4.9 2.4 8.3 0.5 2.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Med21 PF11221.8 KFP12432.1 - 6.5 7.0 12.8 3.4 7.9 3.8 2.6 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SseC PF04888.12 KFP12432.1 - 9.7 5.7 8.8 11 5.5 0.9 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Pentapeptide_4 PF13599.6 KFP12433.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.6 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) RhoGEF PF00621.20 KFP12434.1 - 1.6e-43 149.1 3.1 2.9e-43 148.2 3.1 1.5 1 0 0 1 1 1 1 RhoGEF domain BBS2_Mid PF14783.6 KFP12434.1 - 0.0044 17.1 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PIN_5 PF08745.11 KFP12434.1 - 0.17 11.2 0.6 0.4 10.1 0.6 1.5 1 0 0 1 1 1 0 PINc domain ribonuclease DUF3664 PF12406.8 KFP12434.1 - 3.9 8.2 9.0 0.21 12.2 0.3 3.1 3 0 0 3 3 3 0 Surface protein RELT PF12606.8 KFP12435.1 - 5.1e-19 67.0 0.2 8.1e-19 66.3 0.2 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 TCRP1 PF14944.6 KFP12436.1 - 3.4e-97 325.2 42.8 4e-97 325.0 42.8 1.1 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 PH PF00169.29 KFP12437.1 - 6.9e-10 39.4 0.1 7.9e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP12437.1 - 6.5e-05 23.3 0.9 0.00013 22.4 0.9 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFP12437.1 - 0.0016 18.7 0.1 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_15 PF17339.2 KFP12437.1 - 0.036 14.0 0.0 0.064 13.2 0.0 1.4 1 1 0 1 1 1 0 PH domain Phage_head_chap PF11113.8 KFP12437.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Head assembly gene product Ras PF00071.22 KFP12438.1 - 1.9e-53 180.4 1.2 2.2e-53 180.2 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP12438.1 - 4.9e-32 110.7 0.3 7.8e-32 110.0 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP12438.1 - 6.4e-12 45.3 0.7 7.2e-12 45.1 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP12438.1 - 1.1e-05 25.1 0.6 2.1e-05 24.1 0.6 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP12438.1 - 0.00039 19.9 0.1 0.00051 19.5 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP12438.1 - 0.003 17.6 0.1 0.0056 16.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP12438.1 - 0.0043 17.0 0.1 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase Ribosomal_S10 PF00338.22 KFP12439.1 - 2.8e-11 43.5 0.3 2.3e-10 40.5 0.0 2.3 2 1 0 2 2 2 1 Ribosomal protein S10p/S20e WD40 PF00400.32 KFP12440.1 - 2.4e-18 66.2 10.1 1.8e-05 25.4 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KFP12440.1 - 0.0024 16.7 0.0 1.4 7.6 0.0 2.5 2 1 1 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KFP12440.1 - 0.025 14.9 0.1 17 5.8 0.0 3.6 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP12440.1 - 0.045 13.1 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain ClpB_D2-small PF10431.9 KFP12441.1 - 6.2e-10 39.0 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.14 KFP12441.1 - 3.4e-08 33.8 0.3 9.3e-08 32.4 0.3 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Glypican PF01153.19 KFP12442.1 - 4.3e-207 689.3 0.0 5.1e-207 689.1 0.0 1.0 1 0 0 1 1 1 1 Glypican Fz PF01392.22 KFP12442.1 - 0.059 14.0 0.3 0.13 12.9 0.3 1.5 1 0 0 1 1 1 0 Fz domain Tyrosinase PF00264.20 KFP12443.1 - 8.9e-17 62.1 0.1 2.8e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase GpcrRhopsn4 PF10192.9 KFP12444.1 - 4.9e-81 271.9 5.6 6e-81 271.6 5.6 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KFP12444.1 - 2.8e-08 33.4 4.0 4.8e-08 32.6 3.7 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor PLAC8 PF04749.17 KFP12444.1 - 0.0077 17.2 1.4 0.0077 17.2 1.4 2.4 3 0 0 3 3 3 1 PLAC8 family DUF1146 PF06612.11 KFP12444.1 - 0.031 14.3 0.3 0.12 12.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) WHIM1 PF15612.6 KFP12444.1 - 0.035 13.7 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 MraZ PF02381.18 KFP12444.1 - 0.047 13.7 0.5 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like ABC_membrane PF00664.23 KFP12445.1 - 1.2e-77 261.3 38.7 1.6e-46 159.1 13.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP12445.1 - 8.9e-40 136.4 0.0 2.2e-19 70.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFP12445.1 - 5.6e-10 39.0 2.9 0.54 9.6 0.0 4.3 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFP12445.1 - 1.2e-07 32.3 0.6 0.0031 17.9 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KFP12445.1 - 2.7e-07 30.9 0.2 0.12 12.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KFP12445.1 - 4.8e-07 29.9 0.1 0.0054 16.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KFP12445.1 - 1.1e-06 28.3 0.0 0.038 13.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP12445.1 - 5e-06 26.5 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KFP12445.1 - 1.6e-05 25.1 0.0 0.025 14.6 0.0 2.9 3 0 0 3 3 2 2 Dynamin family AAA_21 PF13304.6 KFP12445.1 - 4.7e-05 23.3 1.5 0.086 12.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFP12445.1 - 0.0004 19.9 0.0 0.9 9.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP12445.1 - 0.0006 19.6 0.2 1.5 8.5 0.0 3.5 3 1 1 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFP12445.1 - 0.00083 19.9 0.0 0.37 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFP12445.1 - 0.0027 16.8 0.0 0.068 12.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KFP12445.1 - 0.018 14.8 0.0 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFP12445.1 - 0.026 14.1 0.2 2.6 7.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KFP12445.1 - 0.029 14.5 2.3 0.24 11.5 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain DUF815 PF05673.13 KFP12445.1 - 0.052 12.7 0.2 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KFP12445.1 - 0.098 11.9 0.2 8.9 5.5 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin Guanylate_kin PF00625.21 KFP12445.1 - 0.11 12.2 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_27 PF13514.6 KFP12445.1 - 0.13 11.8 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KFP12445.1 - 0.16 12.2 0.3 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KFP12445.1 - 0.17 11.5 0.8 6 6.4 0.1 3.1 2 1 1 3 3 3 0 AAA domain MeaB PF03308.16 KFP12445.1 - 0.19 10.7 0.2 6.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dzip-like_N PF13815.6 KFP12446.1 - 2.3e-14 53.4 2.4 2.3e-14 53.4 2.4 6.6 4 2 2 6 6 6 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 KFP12446.1 - 0.029 14.8 4.1 0.073 13.6 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Herpes_glycoH_C PF17488.2 KFP12446.1 - 0.035 13.9 0.2 0.08 12.7 0.2 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain zf-C2H2_4 PF13894.6 KFP12446.1 - 0.035 14.9 3.8 0.14 13.1 3.8 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF384 PF04064.13 KFP12446.1 - 0.61 10.0 2.9 3.7 7.5 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF384) zf-C2H2_3rep PF18868.1 KFP12446.1 - 7 7.3 13.0 0.22 12.2 4.2 3.0 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Pentapeptide_4 PF13599.6 KFP12447.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF2924 PF11149.8 KFP12447.1 - 0.62 10.4 3.9 3.2 8.1 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) TPR_2 PF07719.17 KFP12448.1 - 6.9e-29 97.6 20.3 0.00015 21.7 0.0 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 KFP12448.1 - 4.1e-28 97.7 13.8 3.4e-07 30.7 1.1 6.3 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP12448.1 - 8.3e-28 95.0 20.4 4.4e-07 29.4 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFP12448.1 - 1.2e-22 80.3 6.8 0.00014 22.4 0.8 6.0 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFP12448.1 - 2.3e-21 75.2 12.7 0.00016 21.3 0.3 7.4 5 2 3 8 8 8 6 TPR repeat TPR_8 PF13181.6 KFP12448.1 - 6.4e-21 72.8 21.8 8.1e-05 22.5 0.1 8.4 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP12448.1 - 5.9e-19 67.1 8.9 0.01 16.6 0.0 8.0 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 KFP12448.1 - 9.8e-16 57.7 2.5 0.00051 20.1 0.4 5.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFP12448.1 - 2.2e-13 49.9 11.2 0.3 11.8 0.2 8.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP12448.1 - 8.3e-13 47.8 9.1 0.00077 19.7 0.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP12448.1 - 2.3e-12 47.0 21.0 0.011 16.0 0.1 7.1 2 1 4 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP12448.1 - 7.9e-12 45.2 19.0 4.7e-05 23.5 0.6 5.1 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KFP12448.1 - 1.3e-10 41.4 11.9 4.9e-07 29.7 4.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KFP12448.1 - 1.4e-09 37.3 10.3 2.8 8.2 0.0 8.2 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFP12448.1 - 3.2e-09 37.0 19.3 0.15 12.4 0.0 6.9 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFP12448.1 - 1.5e-06 27.6 7.7 0.12 11.6 0.9 4.8 1 1 4 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP12448.1 - 6.9e-06 26.0 10.2 0.28 11.3 0.8 5.8 5 1 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFP12448.1 - 0.00035 20.3 8.4 1.6 8.7 0.0 6.2 7 1 0 7 7 5 1 Tetratricopeptide repeat COPI_C PF06957.11 KFP12448.1 - 0.0004 19.3 2.2 0.19 10.5 0.0 3.3 1 1 0 3 3 3 2 Coatomer (COPI) alpha subunit C-terminus NARP1 PF12569.8 KFP12448.1 - 0.00051 19.1 13.8 0.0025 16.8 2.7 3.1 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KFP12448.1 - 0.0015 18.9 7.9 0.73 10.6 0.0 5.8 8 0 0 8 8 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFP12448.1 - 0.0045 17.4 10.4 0.99 9.9 0.8 4.6 2 1 2 5 5 5 1 Alkyl sulfatase dimerisation Virulence_fact PF13769.6 KFP12448.1 - 0.037 14.3 0.7 0.15 12.3 0.1 2.4 3 0 0 3 3 1 0 Virulence factor 4HB_MCP_1 PF12729.7 KFP12448.1 - 0.047 13.2 2.9 5.8 6.4 0.1 2.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction PknG_TPR PF16918.5 KFP12448.1 - 0.058 12.1 1.0 0.71 8.5 0.1 2.8 1 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat DUF4363 PF14276.6 KFP12448.1 - 0.099 12.8 0.2 0.099 12.8 0.2 3.9 2 1 1 3 3 2 0 Domain of unknown function (DUF4363) MAS20 PF02064.15 KFP12448.1 - 0.13 12.4 8.0 5.1 7.2 0.0 4.1 4 1 1 5 5 4 0 MAS20 protein import receptor Vta1_C PF18097.1 KFP12448.1 - 2.6 7.8 7.5 0.2 11.4 0.6 2.9 3 0 0 3 3 3 0 Vta1 C-terminal domain TPR_3 PF07720.12 KFP12448.1 - 3.7 7.7 7.1 1.8 8.6 0.3 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KFP12449.1 - 1.3e-08 34.6 1.5 4.4e-08 32.9 1.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP12449.1 - 7.3e-08 32.1 0.6 3e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain Arf PF00025.21 KFP12449.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family PRANC PF09372.10 KFP12449.1 - 0.065 13.6 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 PRANC domain Peptidase_C1 PF00112.23 KFP12450.1 - 7.4e-79 264.9 1.0 8.2e-79 264.7 1.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFP12450.1 - 1.8e-05 23.7 0.4 0.0078 15.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DEAD PF00270.29 KFP12451.1 - 1.1e-21 77.3 0.0 2.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase BDHCT PF08072.11 KFP12451.1 - 8.4e-21 73.8 2.5 1.9e-20 72.6 2.5 1.7 1 0 0 1 1 1 1 BDHCT (NUC031) domain BDHCT_assoc PF16204.5 KFP12451.1 - 1.7e-18 67.1 3.0 4.3e-18 65.8 3.0 1.6 1 0 0 1 1 1 1 BDHCT-box associated domain on Bloom syndrome protein RecQ_Zn_bind PF16124.5 KFP12451.1 - 8.3e-18 64.9 1.7 8.3e-18 64.9 1.7 2.4 2 0 0 2 2 1 1 RecQ zinc-binding Helicase_C PF00271.31 KFP12451.1 - 5.9e-16 58.8 0.0 2.1e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 KFP12451.1 - 8.5e-13 48.1 0.0 2.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain RQC PF09382.10 KFP12451.1 - 9.8e-13 47.9 0.1 2e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KFP12451.1 - 0.00072 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFP12451.1 - 0.0082 14.9 0.0 0.12 11.0 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain BLM_N PF16202.5 KFP12451.1 - 0.022 13.9 9.3 0.023 13.8 4.5 2.6 2 0 0 2 2 2 0 N-terminal region of Bloom syndrome protein HTH_35 PF13693.6 KFP12451.1 - 0.1 12.6 0.7 77 3.4 0.0 3.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding WD40 PF00400.32 KFP12452.1 - 0.00091 20.0 7.9 1.7 9.6 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 KFP12452.1 - 0.0022 16.7 0.2 0.0045 15.7 0.2 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KFP12452.1 - 0.33 11.5 1.0 35 5.0 0.2 3.1 3 0 0 3 3 3 0 PQQ-like domain SlyX PF04102.12 KFP12453.1 - 4.6 7.9 13.0 5.6 7.7 4.1 3.1 1 1 1 2 2 2 0 SlyX FAM76 PF16046.5 KFP12453.1 - 5.1 6.4 17.7 0.11 11.8 9.7 2.1 2 1 0 2 2 2 0 FAM76 protein V_ATPase_I PF01496.19 KFP12453.1 - 6.2 4.6 7.6 11 3.8 7.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NIF PF03031.18 KFP12454.1 - 1.6e-55 187.2 1.0 3.2e-55 186.2 1.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase eIF3_subunit PF08597.10 KFP12455.1 - 5.8e-54 183.6 24.4 6.6e-54 183.4 24.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4462 PF14692.6 KFP12456.1 - 0.18 11.3 0.4 0.84 9.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) DUF4589 PF15252.6 KFP12457.1 - 8.1e-80 268.4 5.2 9.1e-80 268.2 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) MaoC_dehydratas PF01575.19 KFP12459.1 - 2.6e-39 133.6 0.0 4.8e-39 132.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain adh_short PF00106.25 KFP12459.1 - 5.3e-34 117.4 0.0 1.2e-33 116.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP12459.1 - 9.3e-33 113.7 0.0 2.3e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 KFP12459.1 - 8.9e-25 87.1 0.4 1.8e-24 86.1 0.4 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 KFP12459.1 - 4.2e-11 43.1 0.0 7.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.6 KFP12459.1 - 3.7e-08 33.6 0.0 4.1e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.6 KFP12459.1 - 1.4e-06 28.6 0.1 3.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ApoC-I PF04691.12 KFP12459.1 - 0.039 13.9 0.1 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF758 PF05527.11 KFP12460.1 - 1.7e-77 259.5 8.5 1.9e-77 259.4 8.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Pico_P2B PF01552.17 KFP12460.1 - 0.0021 18.2 0.8 0.0042 17.2 0.4 1.9 2 1 0 2 2 2 1 Picornavirus 2B protein NAD_binding_4 PF07993.12 KFP12460.1 - 0.024 13.8 0.1 0.037 13.2 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Nup54 PF13874.6 KFP12460.1 - 0.027 14.6 1.7 0.03 14.4 0.7 1.7 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2408 PF10303.9 KFP12460.1 - 0.032 14.8 4.0 0.058 13.9 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF4771 PF15995.5 KFP12460.1 - 0.039 14.2 0.9 0.05 13.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) HD_3 PF13023.6 KFP12460.1 - 0.045 13.7 0.7 0.098 12.6 0.8 1.5 2 0 0 2 2 2 0 HD domain DUF459 PF04311.13 KFP12460.1 - 0.045 12.8 0.2 0.06 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Peptidase_S46 PF10459.9 KFP12460.1 - 0.11 11.2 1.1 0.13 10.9 1.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Rav1p_C PF12234.8 KFP12462.1 - 4.5e-84 283.1 0.0 5e-74 249.9 0.0 2.6 2 1 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 KFP12462.1 - 2.9e-14 53.2 28.3 0.0091 16.8 0.0 12.4 14 0 0 14 14 14 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP12462.1 - 4.1e-05 23.8 0.0 9.4 6.6 0.0 4.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP12462.1 - 0.15 11.0 0.7 11 4.9 0.0 3.6 5 0 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RVT_1 PF00078.27 KFP12463.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DTW PF03942.15 KFP12465.1 - 5.4e-42 143.7 0.4 6.5e-42 143.5 0.4 1.1 1 0 0 1 1 1 1 DTW domain Sema PF01403.19 KFP12469.1 - 1.7e-134 448.8 0.1 2.6e-134 448.2 0.1 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP12469.1 - 7.1e-07 29.7 3.8 1.9e-06 28.3 3.8 1.7 1 0 0 1 1 1 1 Plexin repeat DUF3481 PF11980.8 KFP12469.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein COMM_domain PF07258.14 KFP12471.1 - 8.5e-06 25.8 3.2 2.2e-05 24.5 0.1 2.4 2 1 0 2 2 2 1 COMM domain ARF7EP_C PF14949.6 KFP12472.1 - 6.7e-37 126.3 12.1 7.6e-37 126.1 12.1 1.0 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Peptidase_M1 PF01433.20 KFP12473.1 - 5.2e-59 199.5 0.3 1.4e-58 198.0 0.3 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFP12473.1 - 2.4e-53 181.7 2.2 3.4e-53 181.2 2.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFP12473.1 - 3.6e-24 86.0 0.5 6.5e-24 85.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Clat_adaptor_s PF01217.20 KFP12475.1 - 1.3e-41 141.9 2.9 1.6e-41 141.6 2.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDO_I PF05995.12 KFP12476.1 - 7.4e-73 243.4 0.1 8.3e-73 243.2 0.1 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KFP12476.1 - 1.5e-05 24.5 0.3 8.5e-05 22.1 0.2 1.9 1 1 0 1 1 1 1 PCO_ADO MFS_1 PF07690.16 KFP12477.1 - 5.2e-22 78.2 23.1 6.3e-22 78.0 23.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.22 KFP12477.1 - 0.03 13.5 2.3 0.44 9.7 1.3 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter RAWUL PF16207.5 KFP12479.1 - 4.1e-16 59.4 0.8 1.1e-15 58.1 0.3 2.0 2 1 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP12479.1 - 8.7e-12 44.7 8.1 2.1e-11 43.5 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP12479.1 - 4e-09 36.2 9.3 4e-09 36.2 9.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP12479.1 - 1e-07 32.1 8.0 1e-07 32.1 8.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP12479.1 - 2.9e-06 27.1 8.4 2.9e-06 27.1 8.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP12479.1 - 2.5e-05 24.2 4.7 2.5e-05 24.2 4.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP12479.1 - 2.7e-05 24.0 9.5 2.7e-05 24.0 9.5 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP12479.1 - 6.4e-05 23.2 4.9 6.4e-05 23.2 4.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP12479.1 - 0.00059 19.9 8.6 0.00059 19.9 8.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP12479.1 - 0.01 15.6 9.4 0.014 15.2 6.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFP12479.1 - 0.021 14.6 3.3 0.038 13.8 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KFP12479.1 - 0.029 14.2 9.8 0.029 14.2 9.8 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 GAGA PF09237.11 KFP12479.1 - 0.031 14.1 0.1 0.099 12.5 0.1 1.8 1 0 0 1 1 1 0 GAGA factor DUF3337 PF11816.8 KFP12479.1 - 0.032 14.1 5.5 0.035 14.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) zf-RING_10 PF16685.5 KFP12479.1 - 0.17 12.0 10.4 0.092 12.9 5.9 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KFP12479.1 - 0.81 9.8 9.8 0.93 9.6 5.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 KFP12479.1 - 1.1 9.5 9.4 0.77 9.9 6.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Synaphin PF05835.12 KFP12481.1 - 1.1e-34 119.7 15.6 1.3e-34 119.6 15.6 1.0 1 0 0 1 1 1 1 Synaphin protein VIT1 PF01988.19 KFP12481.1 - 5.7 6.7 4.4 6.3 6.6 4.4 1.1 1 0 0 1 1 1 0 VIT family ATG101 PF07855.12 KFP12483.1 - 4.9e-35 120.8 0.0 6.6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 101 tRNA_lig_CPD PF08302.11 KFP12483.1 - 0.09 12.2 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Pkinase_Tyr PF07714.17 KFP12484.1 - 3.3e-13 49.5 0.0 3.7e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12484.1 - 3.8e-12 46.1 0.0 4.5e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP12484.1 - 0.00057 19.3 0.8 0.0013 18.2 0.8 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif FTA2 PF13095.6 KFP12484.1 - 0.023 14.3 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SLH PF00395.20 KFP12485.1 - 0.0073 16.3 1.1 2 8.5 0.0 2.3 1 1 1 2 2 2 2 S-layer homology domain Plasmid_RAQPRD PF09686.10 KFP12485.1 - 0.084 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TLV_coat PF00429.19 KFP12486.1 - 0.00056 18.7 0.2 0.00061 18.6 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Epimerase_2 PF02350.19 KFP12487.1 - 1.8e-67 227.7 0.1 2.8e-67 227.1 0.1 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ROK PF00480.20 KFP12487.1 - 5e-56 190.3 2.4 8.5e-56 189.6 2.4 1.4 1 0 0 1 1 1 1 ROK family Hexokinase_1 PF00349.21 KFP12487.1 - 0.0004 20.3 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DRTGG PF07085.12 KFP12487.1 - 0.0016 18.2 0.2 0.0051 16.6 0.2 1.9 1 0 0 1 1 1 1 DRTGG domain FGGY_N PF00370.21 KFP12487.1 - 0.0051 16.4 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFP12487.1 - 0.0091 15.5 1.3 2.9 7.3 0.3 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Glucokinase PF02685.16 KFP12487.1 - 0.16 10.9 2.3 0.29 10.1 0.0 2.4 3 0 0 3 3 3 0 Glucokinase Arf PF00025.21 KFP12488.1 - 1.3e-30 106.1 0.5 1.5e-30 105.9 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP12488.1 - 8.8e-07 29.2 0.1 1.1e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP12488.1 - 7.8e-06 25.4 0.1 8.7e-06 25.3 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP12488.1 - 2e-05 24.0 0.7 0.017 14.3 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFP12488.1 - 4.6e-05 23.1 0.2 5.5e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP12488.1 - 9.4e-05 21.9 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 KFP12488.1 - 0.0031 16.9 0.2 0.0032 16.8 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 KFP12488.1 - 0.024 14.7 0.1 0.036 14.2 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KFP12488.1 - 0.21 11.7 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain PHR PF08005.12 KFP12490.1 - 1.3e-43 149.3 2.1 1.4e-43 149.2 0.9 1.7 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 KFP12490.1 - 5.1e-24 84.6 0.0 3.2e-23 82.1 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP12490.1 - 9.3e-08 32.1 3.5 1.1e-07 31.8 1.4 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch Aminotran_1_2 PF00155.21 KFP12491.1 - 1.7e-58 198.6 0.0 2e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFP12491.1 - 6.6e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFP12491.1 - 0.00071 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Raf1_HTH PF18579.1 KFP12491.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Cyd_oper_YbgE PF09600.10 KFP12491.1 - 0.15 12.4 0.1 35 4.9 0.0 2.5 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) AMOP PF03782.17 KFP12492.1 - 1.2e-24 87.0 5.1 1.2e-24 87.0 5.1 2.0 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.19 KFP12492.1 - 9.2e-07 29.0 12.1 9.2e-07 29.0 12.1 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain Asparaginase_2 PF01112.18 KFP12493.1 - 9.5e-50 169.4 0.3 1.9e-49 168.3 0.3 1.5 1 0 0 1 1 1 1 Asparaginase NUC153 PF08159.12 KFP12494.1 - 2.3e-11 43.3 11.0 6.3e-11 41.9 1.1 3.3 3 0 0 3 3 3 2 NUC153 domain Methyltransf_11 PF08241.12 KFP12495.1 - 8.9e-22 77.6 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP12495.1 - 1.2e-16 61.2 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP12495.1 - 3.9e-15 56.1 0.0 5.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP12495.1 - 4.9e-12 45.9 0.0 8.8e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP12495.1 - 1.4e-11 45.0 0.0 2.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP12495.1 - 3.8e-09 36.2 0.0 6.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KFP12495.1 - 3.7e-05 22.5 0.0 5.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KFP12495.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KFP12495.1 - 0.0015 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KFP12495.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_18 PF12847.7 KFP12495.1 - 0.04 13.8 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KFP12495.1 - 0.051 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Pox_MCEL PF03291.16 KFP12495.1 - 0.12 11.4 0.0 3.1 6.8 0.0 2.0 1 1 1 2 2 2 0 mRNA capping enzyme Methyltransf_7 PF03492.15 KFP12495.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase LRR_8 PF13855.6 KFP12496.1 - 1.1e-30 105.2 40.4 1.9e-13 49.9 4.8 6.1 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFP12496.1 - 1.9e-14 53.5 42.0 0.0055 17.1 0.7 6.8 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP12496.1 - 7.2e-09 35.4 9.9 0.00044 19.8 1.6 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KFP12496.1 - 3.9e-08 33.3 0.1 0.00013 21.9 0.0 3.6 1 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFP12496.1 - 0.00088 18.9 4.7 0.0027 17.3 3.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 KFP12496.1 - 0.003 18.0 0.0 0.0094 16.4 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain fn3 PF00041.21 KFP12496.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain TPKR_C2 PF16920.5 KFP12496.1 - 0.14 12.3 0.9 0.45 10.7 0.2 2.3 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain Kinesin PF00225.23 KFP12497.1 - 4.4e-111 371.0 0.7 4.4e-111 371.0 0.7 3.9 3 1 2 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 KFP12497.1 - 1.7e-24 86.5 0.1 1.7e-24 86.5 0.1 3.1 3 0 0 3 3 3 1 Microtubule binding PX PF00787.24 KFP12497.1 - 3.4e-16 59.2 0.6 3.4e-16 59.2 0.6 3.5 3 1 0 3 3 3 1 PX domain Kinesin_assoc PF16183.5 KFP12497.1 - 2.9e-09 37.3 3.8 1.1e-05 25.6 0.3 6.4 2 2 4 6 6 6 2 Kinesin-associated Yop-YscD_cpl PF16697.5 KFP12497.1 - 1e-05 25.7 1.1 9.7e-05 22.6 0.0 3.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF2326 PF10088.9 KFP12497.1 - 0.0048 16.6 0.0 0.0048 16.6 0.0 3.5 4 0 0 4 4 4 1 Uncharacterised protein conserved in bacteria (DUF2326) AAA_16 PF13191.6 KFP12497.1 - 3.4 8.0 0.0 3.4 8.0 0.0 4.5 3 2 0 3 3 3 0 AAA ATPase domain RRM_1 PF00076.22 KFP12498.1 - 2.4e-26 91.4 0.1 6.3e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP12498.1 - 1.1e-07 31.5 0.1 0.0079 15.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP12498.1 - 1.4e-05 24.9 0.0 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif KH_dom-like PF14714.6 KFP12498.1 - 0.043 14.1 0.1 0.37 11.1 0.1 2.4 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SH3_2 PF07653.17 KFP12499.1 - 2.4e-19 68.7 0.0 3.4e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP12499.1 - 0.0024 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S8 PF00082.22 KFP12500.1 - 1.9e-42 145.6 2.4 2.4e-42 145.2 2.4 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP12500.1 - 1.1e-25 89.5 0.1 2.7e-25 88.2 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFP12500.1 - 1.8e-08 35.0 1.9 3.4e-08 34.2 1.9 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFP12500.1 - 0.028 14.9 0.0 0.058 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family 7tm_1 PF00001.21 KFP12501.1 - 1.2e-46 159.2 24.0 1.5e-46 158.9 24.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12501.1 - 1.3e-05 24.7 27.5 1.8e-05 24.3 27.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FTCD_N PF07837.12 KFP12502.1 - 2.3e-71 239.2 0.0 3.8e-71 238.5 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 KFP12502.1 - 9.1e-69 230.1 0.0 2e-68 229.0 0.0 1.6 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 KFP12502.1 - 1.3e-66 223.9 1.6 1.9e-66 223.3 1.6 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase VWA PF00092.28 KFP12503.1 - 2.3e-82 275.5 4.1 1.6e-28 100.1 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.18 KFP12503.1 - 9.2e-52 172.7 207.1 9.9e-10 38.0 25.2 7.3 1 1 4 5 5 5 3 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFP12503.1 - 1.5e-36 125.3 0.5 2.3e-12 47.5 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain KH_1 PF00013.29 KFP12504.1 - 1.8e-46 155.8 12.2 3.1e-19 68.6 0.5 3.7 3 1 0 3 3 3 3 KH domain KH_2 PF07650.17 KFP12504.1 - 3.9e-11 42.6 1.2 5.5e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 KFP12504.1 - 7.6e-06 25.7 1.1 1.1 9.2 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFP12504.1 - 0.00012 22.1 2.2 0.32 11.1 0.2 2.7 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KFP12504.1 - 0.00044 20.2 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain DUF370 PF04025.12 KFP12504.1 - 0.14 12.3 0.3 0.83 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) PAS_3 PF08447.12 KFP12505.1 - 4.1e-16 59.0 0.2 3.6e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP12505.1 - 1.4e-11 44.6 0.4 8.3e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFP12505.1 - 1.8e-10 40.8 0.0 2.2e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFP12505.1 - 8.3e-05 22.8 0.0 0.065 13.5 0.0 2.4 2 0 0 2 2 2 2 PAS domain dNK PF01712.19 KFP12506.1 - 4e-34 118.3 0.0 5.1e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase SKI PF01202.22 KFP12506.1 - 0.0009 19.4 0.1 0.19 11.8 0.1 2.8 3 0 0 3 3 3 2 Shikimate kinase Thymidylate_kin PF02223.17 KFP12506.1 - 0.0018 18.0 0.2 0.0049 16.6 0.2 1.9 1 1 0 1 1 1 1 Thymidylate kinase Cytidylate_kin PF02224.18 KFP12506.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 KFP12506.1 - 0.094 13.1 0.0 19 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 KFP12507.1 - 9.4e-84 281.5 6.5 4.6e-83 279.2 0.0 2.5 2 0 0 2 2 2 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFP12507.1 - 7.8e-35 118.9 46.0 7.8e-35 118.9 46.0 3.5 2 1 0 2 2 2 1 Glutamine rich N terminal domain of histone deacetylase 4 HLH PF00010.26 KFP12508.1 - 1.4e-15 56.9 0.6 3e-15 55.9 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP12508.1 - 0.0033 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 KFP12508.1 - 0.019 13.7 0.8 0.023 13.4 0.8 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 GDH_N PF12466.8 KFP12508.1 - 0.05 13.8 0.1 0.076 13.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal L27 PF02828.16 KFP12508.1 - 0.1 12.4 0.3 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 L27 domain Ank_2 PF12796.7 KFP12509.1 - 2.6e-23 82.4 0.0 2e-12 47.5 0.0 3.7 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP12509.1 - 9.2e-19 65.6 4.2 0.00081 19.7 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFP12509.1 - 1.9e-18 66.2 0.4 3.3e-07 30.5 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP12509.1 - 3.5e-18 65.2 5.5 0.00036 20.8 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 KFP12509.1 - 7.2e-14 52.0 0.6 2.7e-07 31.0 0.0 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP12509.1 - 9.6e-08 32.3 4.3 2.2e-07 31.1 4.3 1.5 1 0 0 1 1 1 1 SOCS box UCH PF00443.29 KFP12510.1 - 1.5e-39 136.0 0.5 8e-34 117.3 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP12510.1 - 3.1e-18 66.5 0.1 4.4e-17 62.7 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UDPGT PF00201.18 KFP12511.1 - 7.3e-41 140.5 0.1 8e-41 140.4 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP12512.1 - 1.3e-41 143.0 0.0 1.4e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP12513.1 - 1.2e-42 146.4 0.0 1.3e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase CRM1_C PF08767.11 KFP12513.1 - 0.075 12.2 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 CRM1 C terminal UDPGT PF00201.18 KFP12514.1 - 1.8e-41 142.5 0.0 2e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP12515.1 - 4e-43 147.9 0.1 4.4e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KFP12516.1 - 7.6e-212 704.5 0.0 8.8e-212 704.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP12516.1 - 0.00021 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 KFP12516.1 - 0.13 12.3 0.0 0.57 10.2 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Pro_3_hydrox_C PF05373.11 KFP12516.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal SH3_2 PF07653.17 KFP12517.1 - 8.8e-23 79.8 0.1 4.6e-11 42.2 0.2 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFP12517.1 - 1.4e-10 40.6 0.6 2.6e-09 36.6 0.0 2.9 2 1 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP12517.1 - 2.6e-10 40.0 0.2 2.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain ZU5 PF00791.20 KFP12517.1 - 1.1e-08 35.2 0.3 2.4e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP12517.1 - 0.0016 18.5 2.0 0.72 10.0 0.1 3.5 2 1 1 3 3 3 2 Death domain IR1-M PF12185.8 KFP12517.1 - 0.038 13.9 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain NIF PF03031.18 KFP12518.1 - 1.7e-30 105.8 0.2 2.6e-30 105.2 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KFP12518.1 - 7e-08 32.1 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF705 PF05152.12 KFP12518.1 - 0.0017 17.9 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Ubiquitin_2 PF14560.6 KFP12518.1 - 0.013 16.0 0.1 0.034 14.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain TRC8_N PF13705.6 KFP12519.1 - 3.4e-154 514.5 46.6 4e-154 514.2 46.6 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.6 KFP12519.1 - 5.4e-10 39.4 7.2 5.4e-10 39.4 7.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP12519.1 - 3.4e-09 36.4 7.2 9.5e-09 35.0 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP12519.1 - 5e-08 33.1 6.6 1.3e-07 31.8 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP12519.1 - 1.3e-06 28.3 1.2 1.3e-06 28.3 1.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP12519.1 - 4.2e-06 26.5 6.5 4.2e-06 26.5 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP12519.1 - 7.7e-06 25.7 8.7 7.7e-06 25.7 8.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP12519.1 - 3.8e-05 23.5 8.7 3.8e-05 23.5 8.7 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP12519.1 - 0.00018 21.1 4.4 0.00018 21.1 4.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFP12519.1 - 0.0025 17.8 10.4 0.0025 17.8 10.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP12519.1 - 0.016 15.2 6.9 0.041 13.9 6.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP12519.1 - 0.55 9.9 14.8 0.11 12.1 8.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KFP12519.1 - 0.9 9.3 7.7 3.3 7.5 7.7 2.0 1 0 0 1 1 1 0 P-11 zinc finger COE1_HLH PF16423.5 KFP12520.1 - 5.4e-37 125.2 3.0 3.8e-30 103.3 0.4 2.4 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain COE1_DBD PF16422.5 KFP12520.1 - 7.6e-34 117.2 2.5 1e-33 116.7 2.5 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain TIG PF01833.24 KFP12520.1 - 3.2e-12 46.4 0.3 3.2e-12 46.4 0.3 2.5 3 0 0 3 3 3 1 IPT/TIG domain HLH PF00010.26 KFP12520.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ENTH PF01417.20 KFP12521.1 - 2.5e-45 153.6 0.6 4.1e-45 152.8 0.0 1.7 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 KFP12521.1 - 3.2e-05 23.1 0.0 6.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 ANTH domain LSM PF01423.22 KFP12522.1 - 6.3e-10 38.6 0.1 5.7e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 LSM domain Thg1C PF14413.6 KFP12523.1 - 1e-49 167.8 0.2 1.8e-49 167.0 0.2 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KFP12523.1 - 3.1e-35 120.9 0.6 4.9e-35 120.3 0.6 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase HMG_box PF00505.19 KFP12524.1 - 4.4e-23 81.5 1.3 7.4e-23 80.8 1.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP12524.1 - 1.5e-10 41.5 0.5 2.5e-10 40.8 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain Mg_trans_NIPA PF05653.14 KFP12525.1 - 9.7e-132 438.5 16.9 1.1e-131 438.3 16.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP12525.1 - 8.1e-08 32.5 4.4 8.1e-08 32.5 4.4 3.7 3 1 0 3 3 3 1 EamA-like transporter family K1 PF02960.14 KFP12525.1 - 0.29 11.3 9.4 0.065 13.4 2.9 2.7 3 1 0 3 3 3 0 K1 glycoprotein FragX_IP PF05994.11 KFP12526.1 - 0 1330.5 0.1 0 1330.5 0.1 1.4 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KFP12526.1 - 3.4e-09 36.4 4.1 3.4e-09 36.4 4.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1394) zf-CW PF07496.15 KFP12526.1 - 0.05 13.6 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger fn3 PF00041.21 KFP12527.1 - 2.8e-05 24.4 0.3 4.1e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP12527.1 - 0.029 14.9 0.2 0.054 14.1 0.2 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain TLD PF07534.16 KFP12527.1 - 0.098 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TLD Pkinase_Tyr PF07714.17 KFP12528.1 - 9e-92 307.0 0.0 1.2e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12528.1 - 9e-51 172.7 0.0 1.4e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP12528.1 - 1.9e-21 75.9 0.0 4e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP12528.1 - 3.9e-15 55.2 0.3 8.2e-15 54.2 0.3 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFP12528.1 - 1.8e-13 50.9 0.5 5.1e-13 49.4 0.5 1.8 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KFP12528.1 - 3.5e-13 49.2 0.4 7.7e-13 48.1 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain BTK PF00779.19 KFP12528.1 - 8.9e-13 47.8 3.4 1.6e-12 47.0 3.4 1.5 1 0 0 1 1 1 1 BTK motif SH3_2 PF07653.17 KFP12528.1 - 7.3e-07 28.8 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP12528.1 - 6.1e-05 23.2 0.3 0.00019 21.7 0.3 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 KFP12528.1 - 0.00011 22.1 0.0 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PH_8 PF15409.6 KFP12528.1 - 0.00096 19.4 0.4 0.0038 17.5 0.4 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_4 PF06347.13 KFP12528.1 - 0.019 14.8 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RFC1 PF08519.12 KFP12528.1 - 0.073 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Kinase-like PF14531.6 KFP12528.1 - 0.086 12.1 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like PH_11 PF15413.6 KFP12528.1 - 2.3 8.7 4.8 2.7 8.5 2.0 2.6 2 1 0 2 2 1 0 Pleckstrin homology domain Med7 PF05983.11 KFP12529.1 - 3.9e-46 157.5 7.7 3.1e-45 154.6 7.7 1.9 1 1 0 1 1 1 1 MED7 protein DotU PF09850.9 KFP12529.1 - 0.03 14.0 0.5 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU V-set PF07686.17 KFP12530.1 - 4.3e-13 49.4 0.9 8.1e-13 48.5 0.4 1.7 1 1 1 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFP12530.1 - 1.8e-05 24.8 0.1 0.0003 20.9 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12530.1 - 0.0013 18.8 0.1 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12530.1 - 0.0075 16.9 3.4 0.0095 16.5 0.9 2.3 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12530.1 - 0.013 15.8 7.0 0.038 14.3 2.4 2.9 1 1 1 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP12530.1 - 0.042 14.0 0.1 0.33 11.2 0.0 2.3 2 1 1 3 3 3 0 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFP12530.1 - 0.072 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP12531.1 - 4.7e-18 65.3 0.1 7.8e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP12531.1 - 3.1e-05 24.1 0.2 0.0012 19.0 0.1 2.5 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP12531.1 - 0.0052 16.8 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP12531.1 - 0.006 16.9 0.4 0.034 14.5 0.4 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP12531.1 - 0.0068 17.0 0.6 0.055 14.1 0.6 2.5 1 1 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP12531.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFP12531.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Sarcoglycan_1 PF04790.13 KFP12532.1 - 6.7e-80 268.2 0.0 7.6e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFP12532.1 - 0.00021 21.2 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF1523 PF07509.11 KFP12532.1 - 0.084 12.2 0.1 0.19 11.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) Ribosomal_L22 PF00237.19 KFP12533.1 - 2.7e-23 82.2 0.7 4.1e-23 81.6 0.5 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e ANAPC4_WD40 PF12894.7 KFP12534.1 - 2.5e-21 75.8 0.7 9.5e-07 29.0 0.0 6.3 5 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP12534.1 - 1.3e-13 51.2 29.0 0.00051 20.8 0.1 10.4 12 0 0 12 12 12 6 WD domain, G-beta repeat CAF1 PF04857.20 KFP12535.1 - 1.5e-23 83.5 1.6 1.1e-11 44.5 0.1 2.4 1 1 0 2 2 2 2 CAF1 family ribonuclease FA_hydroxylase PF04116.13 KFP12536.1 - 3.8e-21 75.8 16.2 3.8e-21 75.8 16.2 2.7 3 1 1 4 4 4 1 Fatty acid hydroxylase superfamily La PF05383.17 KFP12537.1 - 1.4e-21 76.3 0.8 3.5e-21 75.0 0.2 2.1 2 0 0 2 2 2 1 La domain DUF5320 PF17253.2 KFP12537.1 - 0.029 15.4 2.5 0.095 13.8 0.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) SGP PF17228.2 KFP12537.1 - 5.6 7.9 12.6 0.28 12.0 6.2 2.1 2 0 0 2 2 2 0 Sulphur globule protein SAP30_Sin3_bdg PF13867.6 KFP12538.1 - 3.5e-26 91.3 0.7 6.5e-26 90.4 0.7 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 KFP12538.1 - 6.8e-13 48.5 2.0 6.8e-13 48.5 2.0 1.7 2 0 0 2 2 2 1 SAP30 zinc-finger AMOP PF03782.17 KFP12540.1 - 1.2e-51 174.6 6.7 2.8e-51 173.4 6.7 1.7 1 0 0 1 1 1 1 AMOP domain VWD PF00094.25 KFP12540.1 - 1.7e-16 60.9 0.2 5e-16 59.4 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type D domain Sushi PF00084.20 KFP12540.1 - 1.5e-08 35.1 0.7 6.5e-08 33.1 0.7 2.2 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) Somatomedin_B PF01033.17 KFP12540.1 - 2e-06 28.1 12.5 2e-06 28.1 12.5 2.4 2 0 0 2 2 2 1 Somatomedin B domain Porin_7 PF16956.5 KFP12540.1 - 0.051 13.2 0.7 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Putative general bacterial porin CUB PF00431.20 KFP12541.1 - 4.3e-20 72.1 0.0 1e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 CUB domain Kringle PF00051.18 KFP12541.1 - 2.7e-19 69.3 7.2 6.7e-19 68.0 7.2 1.7 1 0 0 1 1 1 1 Kringle domain WSC PF01822.19 KFP12541.1 - 2.5e-17 62.8 9.4 2.5e-17 62.8 9.4 1.8 2 0 0 2 2 2 1 WSC domain ZNRF_3_ecto PF18212.1 KFP12542.1 - 5e-47 158.2 0.0 8.8e-47 157.4 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 KFP12542.1 - 1.3e-11 44.6 9.5 1.3e-11 44.6 9.5 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 KFP12542.1 - 2.7e-11 43.0 3.4 1.3e-10 40.8 2.5 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP12542.1 - 7.5e-08 32.1 9.1 7.5e-08 32.1 9.1 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP12542.1 - 3.4e-06 26.8 8.7 3.4e-06 26.8 8.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP12542.1 - 5.3e-05 23.0 6.5 0.00025 20.8 6.5 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP12542.1 - 9.6e-05 22.3 7.7 0.00044 20.2 7.7 2.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP12542.1 - 0.00044 20.2 7.4 0.00078 19.4 5.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP12542.1 - 0.00074 19.3 6.7 0.00074 19.3 6.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP12542.1 - 0.00087 19.5 12.7 0.00087 19.5 12.7 2.8 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP12542.1 - 0.022 14.8 3.3 0.092 12.8 3.3 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PA PF02225.22 KFP12542.1 - 0.045 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 1 0 PA domain Cadherin_C_2 PF16492.5 KFP12542.1 - 0.18 12.6 2.2 0.19 12.5 0.2 2.1 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal Baculo_RING PF05883.11 KFP12542.1 - 0.21 11.5 1.1 0.88 9.6 0.3 2.2 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain CCDC117 PF15810.5 KFP12543.1 - 6.4e-60 201.6 0.7 8.4e-60 201.2 0.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 Sugar_tr PF00083.24 KFP12544.1 - 1.1e-96 324.5 20.9 1.3e-96 324.2 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP12544.1 - 1.6e-19 70.1 32.0 8.4e-19 67.7 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.10 KFP12544.1 - 0.035 14.4 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Romo1 PF10247.9 KFP12544.1 - 5.3 7.5 17.1 0.7 10.3 0.4 3.8 3 1 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Pkinase PF00069.25 KFP12545.1 - 3.8e-75 252.7 0.0 4.8e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12545.1 - 2e-32 112.5 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFP12545.1 - 4.1e-13 49.5 0.0 8.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFP12545.1 - 2.2e-08 33.8 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP12545.1 - 0.0057 15.5 0.1 0.011 14.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFP12545.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP12545.1 - 0.011 14.8 0.1 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 KFP12545.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KFP12545.1 - 0.22 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.6 KFP12546.1 - 7e-104 340.3 109.5 7.4e-13 48.6 0.4 16.0 12 2 6 18 18 18 15 Tetratricopeptide repeat TPR_7 PF13176.6 KFP12546.1 - 1.1e-90 291.3 88.9 2e-07 30.5 0.8 25.2 25 0 0 25 25 25 18 Tetratricopeptide repeat TPR_1 PF00515.28 KFP12546.1 - 2.1e-75 245.7 100.2 2.3e-07 30.3 1.0 23.0 23 0 0 23 23 23 18 Tetratricopeptide repeat CHAT PF12770.7 KFP12546.1 - 6.6e-75 252.2 0.2 1.4e-74 251.2 0.2 1.6 1 0 0 1 1 1 1 CHAT domain TPR_8 PF13181.6 KFP12546.1 - 8.5e-48 156.6 83.0 1.2e-07 31.4 0.5 24.6 25 2 2 27 27 26 11 Tetratricopeptide repeat TPR_2 PF07719.17 KFP12546.1 - 6.6e-43 141.4 101.6 1.3e-06 28.0 1.7 23.9 26 0 0 26 26 23 10 Tetratricopeptide repeat TPR_10 PF13374.6 KFP12546.1 - 4.3e-36 121.8 83.5 7.8e-05 22.4 0.2 22.8 23 1 0 24 24 23 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP12546.1 - 2.3e-24 86.4 66.3 2.7e-09 36.9 6.6 9.5 3 1 5 9 9 9 5 MalT-like TPR region TPR_14 PF13428.6 KFP12546.1 - 7.9e-16 57.4 59.8 0.11 13.4 0.6 20.7 20 5 5 25 25 21 3 Tetratricopeptide repeat Rapsyn_N PF10579.9 KFP12546.1 - 6.8e-12 45.3 20.3 0.051 13.7 0.1 10.9 9 2 3 12 12 11 2 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.14 KFP12546.1 - 8.3e-10 38.3 31.8 2 9.3 0.8 14.1 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP12546.1 - 2.3e-07 31.2 56.6 0.11 13.0 0.9 11.6 10 2 2 12 12 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP12546.1 - 9.2e-07 28.4 58.0 0.0054 16.4 0.0 15.9 14 4 1 15 15 15 3 TPR repeat RPN7 PF10602.9 KFP12546.1 - 1.5e-06 28.1 29.4 0.05 13.3 1.4 7.8 5 2 1 6 6 6 2 26S proteasome subunit RPN7 TPR_17 PF13431.6 KFP12546.1 - 1e-05 25.6 45.6 0.75 10.3 0.5 14.8 16 0 0 16 16 15 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP12546.1 - 8.3e-05 23.1 63.0 0.0043 17.7 0.1 12.1 13 2 1 14 14 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP12546.1 - 0.00017 21.6 45.7 0.015 15.4 0.1 11.0 10 3 0 11 11 10 3 Tetratricopeptide repeat ANAPC5 PF12862.7 KFP12546.1 - 0.007 16.4 22.0 0.18 11.9 0.0 8.2 8 1 0 9 9 8 1 Anaphase-promoting complex subunit 5 PUB PF09409.10 KFP12546.1 - 0.017 15.0 0.0 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 PUB domain TPR_6 PF13174.6 KFP12546.1 - 0.062 14.0 0.1 0.062 14.0 0.1 14.8 19 0 0 19 19 13 0 Tetratricopeptide repeat HisKA_3 PF07730.13 KFP12546.1 - 2.3 8.8 7.0 3.9 8.1 0.0 4.7 4 0 0 4 4 3 0 Histidine kinase IP_trans PF02121.18 KFP12547.1 - 1.1e-108 362.4 2.4 1.3e-108 362.3 2.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Crystall PF00030.19 KFP12548.1 - 2e-39 133.7 0.4 2.9e-28 97.9 0.2 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFP12548.1 - 4.2e-06 26.6 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KFP12548.1 - 0.00039 20.5 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFP12548.1 - 0.0086 16.3 0.0 28 5.0 0.0 3.1 1 1 1 3 3 3 2 Interleukin-4 inducing immunoglobulin-binding domain Sulfotransfer_3 PF13469.6 KFP12549.1 - 2.1e-54 185.2 0.0 3.6e-54 184.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFP12549.1 - 3.9e-07 29.8 0.1 3.1e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain GCFC PF07842.12 KFP12550.1 - 1.3e-98 330.0 18.2 4.6e-98 328.2 15.7 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFP12550.1 - 1.3e-16 60.2 4.3 2.4e-16 59.4 4.3 1.5 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KFP12550.1 - 3.3e-05 24.2 1.5 3.3e-05 24.2 1.5 2.2 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KFP12550.1 - 0.00016 21.7 1.1 0.00048 20.2 1.1 1.8 1 0 0 1 1 1 1 G-patch domain Asp_Arg_Hydrox PF05118.15 KFP12551.1 - 3.4e-25 88.7 0.0 5.4e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Zip PF02535.22 KFP12555.1 - 5.5e-67 226.3 5.1 6.9e-67 226.0 5.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4271 PF14093.6 KFP12555.1 - 0.0028 17.6 4.3 0.0028 17.6 4.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4271) TIR_3 PF18567.1 KFP12556.1 - 2.4e-46 157.0 0.3 4.2e-46 156.2 0.3 1.4 1 0 0 1 1 1 1 Toll/interleukin-1 receptor domain DBB PF14545.6 KFP12556.1 - 1.3e-40 138.5 0.0 2.1e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Ank_2 PF12796.7 KFP12556.1 - 0.0025 18.4 0.0 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Metallophos PF00149.28 KFP12558.1 - 1.8e-38 133.1 0.0 2.9e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Endomucin PF07010.12 KFP12561.1 - 4e-31 108.9 0.1 4.8e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 Endomucin Pilin_N PF07790.11 KFP12561.1 - 0.097 13.6 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal ECSCR PF15820.5 KFP12561.1 - 0.42 10.4 2.1 0.82 9.5 2.1 1.5 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Sel1 PF08238.12 KFP12562.1 - 3.8e-09 36.9 0.5 7.8e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 Sel1 repeat DUF3390 PF11870.8 KFP12562.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Histone PF00125.24 KFP12563.1 - 1.8e-19 70.4 0.0 2e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP12563.1 - 0.003 17.8 0.0 0.0042 17.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KFP12563.1 - 0.0056 16.4 0.2 0.014 15.1 0.2 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A MAPKK1_Int PF08923.10 KFP12564.1 - 6.4e-46 155.0 0.0 7.1e-46 154.9 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting SH2 PF00017.24 KFP12565.1 - 6.3e-20 71.1 0.5 1.1e-19 70.2 0.5 1.4 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFP12565.1 - 7.5e-19 68.2 0.7 1.5e-18 67.3 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP12565.1 - 0.00038 20.8 1.5 0.0017 18.7 1.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Vitellogenin_N PF01347.22 KFP12567.1 - 2e-65 221.4 7.5 2.4e-65 221.1 7.5 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region HEAT_2 PF13646.6 KFP12567.1 - 0.038 14.4 0.3 6 7.3 0.1 2.5 2 0 0 2 2 2 0 HEAT repeats tRNA_m1G_MT PF01746.21 KFP12568.1 - 2.2e-29 102.5 0.4 3.9e-29 101.7 0.4 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase ASC PF00858.24 KFP12568.1 - 0.013 14.5 1.6 0.016 14.2 1.6 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel FRG2 PF15315.6 KFP12568.1 - 0.061 13.5 9.8 0.099 12.8 9.8 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 NARP1 PF12569.8 KFP12568.1 - 0.16 10.8 11.0 0.24 10.3 11.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 KFP12568.1 - 1.3 7.2 10.3 1.8 6.8 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFP12568.1 - 1.7 7.4 2.6 1.5 7.5 2.6 1.1 1 0 0 1 1 1 0 Presenilin SPATIAL PF15256.6 KFP12569.1 - 2e-21 77.3 0.7 2.3e-21 77.0 0.7 1.0 1 0 0 1 1 1 1 SPATIAL ADH_zinc_N PF00107.26 KFP12570.1 - 1.3e-26 93.1 0.1 2.4e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP12570.1 - 3.7e-25 87.9 3.8 4.6e-25 87.6 1.9 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.14 KFP12570.1 - 0.0074 15.9 0.3 0.013 15.1 0.3 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IGFBP PF00219.18 KFP12570.1 - 0.0088 16.7 0.2 0.026 15.2 0.2 1.8 1 0 0 1 1 1 1 Insulin-like growth factor binding protein 2-Hacid_dh_C PF02826.19 KFP12570.1 - 0.028 13.8 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KFP12570.1 - 0.11 13.5 0.0 0.2 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KFP12570.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N PF08240.12 KFP12571.1 - 2.3e-25 88.6 0.3 4.9e-25 87.5 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFP12571.1 - 4.9e-25 88.0 0.1 8.6e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFP12571.1 - 9.5e-05 22.0 0.4 0.0006 19.4 0.2 2.1 2 1 1 3 3 3 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KFP12571.1 - 0.023 14.3 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KFP12571.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KFP12571.1 - 0.11 11.9 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 KFP12572.1 - 5.8e-53 179.7 0.4 7.3e-53 179.4 0.4 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFP12572.1 - 0.0043 17.3 1.1 0.0043 17.3 1.1 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Pyr_redox_dim PF02852.22 KFP12572.1 - 0.015 15.6 0.2 0.027 14.7 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain ATP-cone PF03477.16 KFP12572.1 - 0.17 12.5 0.0 2 9.0 0.0 2.2 2 0 0 2 2 2 0 ATP cone domain IF4E PF01652.18 KFP12573.1 - 2.9e-56 189.7 0.2 3.4e-56 189.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tetraspanin PF00335.20 KFP12574.1 - 3e-62 210.3 9.7 3.5e-62 210.1 9.7 1.0 1 0 0 1 1 1 1 Tetraspanin family Pkinase_Tyr PF07714.17 KFP12576.1 - 9.6e-38 129.9 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12576.1 - 3.9e-36 124.8 0.0 6.3e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP12576.1 - 4.3e-16 58.1 0.5 9.1e-16 57.1 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KFP12576.1 - 6.5e-10 40.0 2.1 7.5e-10 39.8 0.8 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain FTA2 PF13095.6 KFP12576.1 - 0.008 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 LRRC37AB_C PF14914.6 KFP12576.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Haspin_kinase PF12330.8 KFP12576.1 - 0.079 11.9 0.1 0.13 11.1 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP12576.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP12576.1 - 0.28 10.7 0.7 26 4.3 0.1 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase LIM PF00412.22 KFP12577.1 - 7.5e-40 135.0 28.2 5.4e-14 52.2 4.3 3.4 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 KFP12577.1 - 1.4e-12 47.7 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 KFP12577.1 - 1.2e-07 32.7 4.4 5.5e-07 30.6 4.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_6 PF17820.1 KFP12577.1 - 9.8e-05 22.1 0.1 0.00022 21.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP12577.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain 7tm_1 PF00001.21 KFP12579.1 - 2.2e-54 184.6 17.5 2.7e-54 184.3 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12579.1 - 8.2e-17 61.4 14.6 1e-16 61.1 14.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP12579.1 - 1.9e-14 53.9 17.8 3e-14 53.3 17.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP12579.1 - 3.4e-07 30.3 5.1 3.4e-07 30.3 5.1 2.5 2 1 0 2 2 2 1 Olfactory receptor Git3 PF11710.8 KFP12579.1 - 0.0034 17.2 12.0 0.0034 17.2 12.0 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 CcmH PF03918.14 KFP12579.1 - 0.094 12.0 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein SNARE PF05739.19 KFP12579.1 - 0.68 10.0 3.4 12 6.0 0.4 2.7 2 0 0 2 2 2 0 SNARE domain DUF4282 PF14110.6 KFP12579.1 - 0.82 10.4 10.0 0.17 12.6 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) Baculo_11_kDa PF06143.11 KFP12579.1 - 5.9 6.5 6.7 1.1 8.9 0.3 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family GST_C_3 PF14497.6 KFP12580.1 - 3.3e-17 62.5 0.0 5.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP12580.1 - 4.6e-12 46.1 0.0 9.5e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP12580.1 - 2.9e-06 27.4 0.1 4.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP12580.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KFP12580.1 - 0.0021 18.8 0.0 0.0036 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 KFP12580.1 - 0.0043 17.3 0.0 0.0084 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP12580.1 - 0.024 14.7 0.5 0.1 12.6 0.5 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KFP12580.1 - 0.024 14.4 0.1 0.069 13.0 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 KFP12582.1 - 1.8e-58 197.9 1.5 3e-58 197.2 1.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP12582.1 - 3.8e-18 65.8 0.3 2.1e-17 63.5 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP12582.1 - 9.6e-09 35.5 0.0 4.9e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFP12582.1 - 2.3e-06 27.0 0.1 8e-06 25.2 0.1 1.9 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CUE PF02845.16 KFP12582.1 - 6.3e-05 22.6 0.4 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 CUE domain HHH_3 PF12836.7 KFP12582.1 - 0.0072 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pre-PUA PF17832.1 KFP12582.1 - 0.055 14.2 2.0 28 5.5 0.0 3.8 3 0 0 3 3 3 0 Pre-PUA-like domain RGS PF00615.19 KFP12583.1 - 1.8e-35 121.8 1.2 2.1e-35 121.5 1.2 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain TFIIS_M PF07500.14 KFP12584.1 - 2.8e-38 130.8 3.7 2.8e-38 130.8 3.7 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFP12584.1 - 1.6e-18 66.2 8.0 3.4e-18 65.2 8.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFP12584.1 - 7.1e-16 58.0 1.3 7.1e-16 58.0 1.3 2.3 3 0 0 3 3 3 1 TFIIS helical bundle-like domain DBD_Tnp_Mut PF03108.15 KFP12584.1 - 0.0028 17.6 0.2 0.0058 16.6 0.2 1.5 1 0 0 1 1 1 1 MuDR family transposase AIM3 PF17096.5 KFP12584.1 - 0.11 13.5 2.5 0.27 12.2 2.5 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Talin_middle PF09141.10 KFP12584.1 - 0.14 12.2 3.4 1.6 8.7 0.1 2.6 2 1 0 3 3 3 0 Talin, middle domain HMA PF00403.26 KFP12584.1 - 0.15 12.5 3.5 0.23 11.9 0.0 2.9 3 0 0 3 3 3 0 Heavy-metal-associated domain PRP1_N PF06424.12 KFP12585.1 - 2e-47 161.3 9.5 4.9e-47 160.1 9.5 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KFP12585.1 - 7.4e-31 104.2 26.4 0.0019 18.9 0.1 13.6 6 3 9 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFP12585.1 - 3.7e-24 85.0 10.5 9.3e-07 29.3 0.1 9.1 7 2 4 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFP12585.1 - 3.7e-12 45.7 0.7 0.14 12.6 0.0 8.9 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP12585.1 - 8.8e-10 39.1 12.8 0.00081 20.0 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP12585.1 - 1e-09 37.7 12.3 0.079 13.1 0.0 10.0 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP12585.1 - 1.1e-07 31.5 0.1 0.34 11.2 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 KFP12585.1 - 2.9e-07 30.8 1.4 0.098 12.6 0.0 5.5 6 0 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 KFP12585.1 - 2.3e-05 24.0 0.6 0.37 10.7 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat FAT PF02259.23 KFP12585.1 - 9.7e-05 21.7 15.4 0.1 11.8 1.0 4.6 1 1 3 4 4 4 2 FAT domain TPR_9 PF13371.6 KFP12585.1 - 0.00013 22.1 2.5 19 5.5 0.0 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFP12585.1 - 0.0055 16.4 7.9 0.29 10.8 1.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 KFP12585.1 - 0.012 15.9 6.7 29 5.1 0.1 6.3 5 1 0 6 6 6 0 Tetratricopeptide repeat SURF2 PF05477.11 KFP12585.1 - 0.76 9.4 6.2 48 3.5 0.0 2.4 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) zf-C2H2_4 PF13894.6 KFP12586.1 - 1.2e-10 41.3 46.3 0.038 14.8 0.8 8.3 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP12586.1 - 2.6e-09 37.0 40.3 0.004 17.5 0.6 8.0 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP12586.1 - 8.2e-09 35.5 20.6 0.034 14.4 0.3 5.8 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 KFP12586.1 - 1.6e-05 23.7 11.1 0.49 8.8 0.8 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF629) zf-BED PF02892.15 KFP12586.1 - 6.9e-05 22.8 32.4 0.46 10.5 0.3 6.4 5 1 1 6 6 6 4 BED zinc finger zf-C2H2_2 PF12756.7 KFP12586.1 - 0.00038 20.7 27.2 0.22 11.9 0.2 6.3 4 2 2 6 6 6 3 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 KFP12586.1 - 0.00073 19.6 14.8 0.3 11.1 0.2 4.6 3 1 1 4 4 4 2 CpXC protein zf-met PF12874.7 KFP12586.1 - 0.001 19.4 24.7 0.86 10.1 0.3 6.0 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP12586.1 - 0.0012 18.6 19.5 0.42 10.4 0.1 5.5 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KFP12586.1 - 0.0016 18.6 29.9 0.076 13.2 0.4 5.3 4 1 1 5 5 5 3 Aberrant zinc-finger zf-FCS PF06467.14 KFP12586.1 - 0.026 14.4 7.9 0.2 11.6 0.2 4.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 KFP12586.1 - 0.034 14.8 16.1 0.088 13.5 0.3 4.7 3 2 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats DUF1610 PF07754.11 KFP12586.1 - 0.088 12.8 0.4 0.088 12.8 0.4 2.6 2 0 0 2 2 1 0 Domain of unknown function (DUF1610) zf-Di19 PF05605.12 KFP12586.1 - 0.45 10.8 27.2 0.13 12.5 0.9 5.4 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_7 PF02591.15 KFP12586.1 - 0.54 10.5 8.8 9.3 6.5 0.1 4.3 5 0 0 5 5 4 0 C4-type zinc ribbon domain zinc_ribbon_9 PF14369.6 KFP12586.1 - 2.2 8.6 8.2 31 4.9 0.3 4.4 4 0 0 4 4 4 0 zinc-ribbon zf-AN1 PF01428.16 KFP12586.1 - 3.2 8.0 23.0 4.5 7.5 1.1 4.9 4 0 0 4 4 4 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFP12586.1 - 3.3 7.9 22.2 6.1 7.1 2.0 5.7 5 0 0 5 5 5 0 Zinc ribbon domain DnaJ PF00226.31 KFP12587.1 - 5.1e-28 97.0 2.5 8.4e-28 96.3 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 KFP12587.1 - 0.82 8.1 7.0 0.91 7.9 7.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TPD52 PF04201.15 KFP12588.1 - 9.8e-68 226.8 5.4 3.9e-38 130.6 0.4 2.0 1 1 1 2 2 2 2 Tumour protein D52 family Lzipper-MIP1 PF14389.6 KFP12588.1 - 0.054 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 HIP1_clath_bdg PF16515.5 KFP12588.1 - 0.18 12.4 3.8 5.6 7.6 0.5 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 G-patch PF01585.23 KFP12589.1 - 3e-12 46.2 0.4 7.2e-12 45.0 0.4 1.6 1 0 0 1 1 1 1 G-patch domain zf-CCCH_4 PF18044.1 KFP12589.1 - 2.4e-05 24.0 4.6 3.8e-05 23.4 4.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP12589.1 - 0.00034 20.6 3.0 0.00062 19.7 3.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Agenet PF05641.12 KFP12589.1 - 0.0035 17.8 0.1 0.012 16.1 0.1 1.9 1 0 0 1 1 1 1 Agenet domain Tudor_2 PF18104.1 KFP12589.1 - 0.0049 16.5 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain G-patch_2 PF12656.7 KFP12589.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 G-patch domain Med21 PF11221.8 KFP12589.1 - 0.3 11.3 10.1 0.046 14.0 0.9 3.0 2 2 0 2 2 2 0 Subunit 21 of Mediator complex zf-CCCH_2 PF14608.6 KFP12589.1 - 0.41 11.2 6.1 0.69 10.5 6.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KFP12589.1 - 0.47 10.4 2.7 0.83 9.6 2.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MCD_N PF17408.2 KFP12589.1 - 0.69 10.1 2.9 0.72 10.0 0.3 2.3 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain NOA36 PF06524.12 KFP12589.1 - 2.3 7.5 11.6 5 6.4 11.6 1.5 1 0 0 1 1 1 0 NOA36 protein Arf PF00025.21 KFP12590.1 - 1.5e-46 158.0 0.1 2e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP12590.1 - 1.4e-14 54.0 0.1 1.7e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP12590.1 - 6.1e-14 52.3 0.1 8.2e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFP12590.1 - 4.5e-11 42.5 0.2 9.4e-07 28.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFP12590.1 - 5.1e-10 39.1 0.0 6.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP12590.1 - 5.9e-08 32.8 0.0 8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP12590.1 - 4.8e-07 29.4 0.0 5.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 KFP12590.1 - 0.031 14.8 0.1 0.052 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain Stathmin PF00836.19 KFP12591.1 - 2.2e-49 166.9 15.1 2.7e-49 166.6 15.1 1.1 1 0 0 1 1 1 1 Stathmin family HrpF PF06266.12 KFP12591.1 - 0.11 12.8 0.4 0.19 12.0 0.4 1.4 1 0 0 1 1 1 0 HrpF protein UPF0242 PF06785.11 KFP12591.1 - 0.39 10.8 10.0 0.43 10.6 10.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KNOX2 PF03791.13 KFP12591.1 - 3.8 7.1 7.8 1.1 8.9 0.1 2.8 2 1 1 3 3 3 0 KNOX2 domain DUF5581 PF17744.1 KFP12592.1 - 4.9e-112 374.3 6.6 5.4e-112 374.2 6.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5581) fn3 PF00041.21 KFP12592.1 - 7e-05 23.1 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP12592.1 - 0.084 13.5 0.2 0.15 12.7 0.2 1.4 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Cypo_polyhedrin PF05865.11 KFP12592.1 - 0.14 11.5 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Cypovirus polyhedrin protein C1-set PF07654.15 KFP12593.1 - 5.3e-21 74.8 4.2 5.3e-15 55.6 0.1 4.2 3 1 2 5 5 4 2 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFP12593.1 - 1.3e-15 57.8 12.6 4.8e-07 30.3 0.0 4.6 4 1 1 5 5 5 2 Immunoglobulin domain ig PF00047.25 KFP12593.1 - 1.2e-13 51.1 1.9 6.9e-06 26.1 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP12593.1 - 1.7e-12 47.2 7.0 6.4e-08 32.6 0.4 4.3 4 1 1 5 5 5 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP12593.1 - 2.7e-12 46.8 0.6 1.8e-09 37.7 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.16 KFP12593.1 - 1.2e-11 44.5 2.0 0.00035 20.6 0.0 4.4 5 0 0 5 5 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP12593.1 - 3.4e-10 40.1 5.1 0.0016 18.8 0.2 4.9 3 1 2 5 5 5 2 Immunoglobulin domain SIT PF15330.6 KFP12593.1 - 6.3e-05 23.4 0.9 0.00017 22.0 0.7 1.9 1 1 1 2 2 2 2 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 KFP12593.1 - 0.00057 19.8 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family MerB PF03243.15 KFP12593.1 - 0.0059 16.7 0.9 0.69 10.1 0.0 2.7 3 0 0 3 3 2 1 Alkylmercury lyase Insulin_TMD PF17870.1 KFP12593.1 - 0.0077 16.3 0.7 0.018 15.1 0.7 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Amnionless PF14828.6 KFP12593.1 - 0.017 14.0 0.1 0.023 13.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KFP12593.1 - 0.05 14.5 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4987 PF16377.5 KFP12593.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Orf78 PF06024.12 KFP12593.1 - 0.12 12.6 2.2 0.14 12.5 0.7 1.8 1 1 1 2 2 2 0 Orf78 (ac78) OAD_gamma PF04277.13 KFP12593.1 - 0.13 12.9 0.0 0.36 11.4 0.0 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CD225 PF04505.12 KFP12593.1 - 0.14 12.3 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein TMEM72 PF16054.5 KFP12593.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 Sun2_CC2 PF18580.1 KFP12593.1 - 0.19 12.0 0.2 18 5.6 0.0 2.5 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 DUF4349 PF14257.6 KFP12593.1 - 0.51 9.8 0.0 0.51 9.8 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) V-set PF07686.17 KFP12594.1 - 2.6e-15 56.5 0.1 4.6e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12594.1 - 1e-12 48.5 0.2 2.1e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP12594.1 - 3.4e-11 43.2 0.3 6e-11 42.4 0.3 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12594.1 - 6.8e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP12594.1 - 1.2e-06 28.7 0.0 2.9e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain BatD PF13584.6 KFP12594.1 - 0.00094 18.1 0.1 0.34 9.7 0.0 2.1 2 0 0 2 2 2 2 Oxygen tolerance DAG1 PF05454.11 KFP12594.1 - 0.036 13.4 0.1 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CcmD PF04995.14 KFP12594.1 - 0.043 13.9 1.5 0.066 13.3 1.5 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) C2-set_2 PF08205.12 KFP12594.1 - 0.053 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP12594.1 - 0.091 12.3 0.3 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Syndecan PF01034.20 KFP12594.1 - 0.2 11.6 0.2 0.36 10.8 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain LST1 PF05083.13 KFP12594.1 - 2.7 8.3 5.6 10 6.5 0.1 2.6 3 0 0 3 3 3 0 LST-1 protein SEP PF08059.13 KFP12595.1 - 8.3e-27 93.6 0.3 2.5e-26 92.0 0.1 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFP12595.1 - 1e-19 70.5 0.1 2e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 UBX domain FKBP_C PF00254.28 KFP12596.1 - 3.4e-27 94.6 0.0 3.7e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pyridoxal_deC PF00282.19 KFP12597.1 - 4.5e-18 65.1 0.0 7.6e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFP12597.1 - 7.5e-14 51.5 0.0 4.8e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP12597.1 - 0.0095 15.2 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 KFP12597.1 - 0.035 12.8 0.0 0.09 11.4 0.0 1.7 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 KFP12597.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pterin_4a PF01329.19 KFP12598.1 - 4e-31 107.0 0.0 4.4e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase UPA PF17217.3 KFP12599.1 - 1.5e-63 212.9 0.0 2.5e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KFP12599.1 - 2e-30 105.0 0.0 4.3e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 KFP12599.1 - 2.7e-11 43.9 0.0 1.4e-07 32.0 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.19 KFP12599.1 - 9.2e-11 41.8 25.8 1.6e-07 31.4 9.9 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain I-set PF07679.16 KFP12599.1 - 1.1e-10 41.4 0.0 3.6e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KFP12599.1 - 1.2e-06 28.6 0.0 3.4e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12599.1 - 1.3e-05 25.5 0.0 0.00034 20.9 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Nucleoside_tran PF01733.18 KFP12600.1 - 2.7e-59 201.1 10.2 2.7e-59 201.1 10.2 2.6 1 1 1 2 2 2 1 Nucleoside transporter DUF4191 PF13829.6 KFP12600.1 - 4.2 6.6 4.7 40 3.5 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Mnd1 PF03962.15 KFP12602.1 - 8.6e-30 102.8 1.5 1.3e-29 102.3 0.2 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain Penicillinase_R PF03965.16 KFP12602.1 - 9.1e-07 29.2 0.4 1.3e-06 28.7 0.3 1.3 1 1 0 1 1 1 1 Penicillinase repressor DivIC PF04977.15 KFP12602.1 - 1.1e-06 28.3 10.7 4e-05 23.3 1.7 2.3 1 1 1 2 2 2 2 Septum formation initiator Seryl_tRNA_N PF02403.22 KFP12602.1 - 0.017 15.4 6.0 0.031 14.5 6.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DsrD PF08679.11 KFP12602.1 - 0.055 13.7 0.1 0.055 13.7 0.1 2.1 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) TrmB PF01978.19 KFP12602.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DASH_Spc19 PF08287.11 KFP12602.1 - 0.088 12.7 9.1 0.14 12.0 9.1 1.4 1 0 0 1 1 1 0 Spc19 FapA PF03961.13 KFP12602.1 - 0.13 10.8 4.7 0.19 10.3 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3896 PF13035.6 KFP12602.1 - 0.22 11.7 2.2 0.97 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) AAA_23 PF13476.6 KFP12602.1 - 0.57 10.7 8.8 0.8 10.2 8.8 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran_CTD PF16326.5 KFP12602.1 - 0.61 10.4 12.0 1.4 9.2 12.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Spc7 PF08317.11 KFP12602.1 - 1.1 8.1 15.8 0.31 9.9 1.3 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4140 PF13600.6 KFP12602.1 - 1.9 9.0 9.4 5.1 7.6 0.6 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KFP12602.1 - 3.1 8.4 14.1 5.9 7.4 14.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KFP12602.1 - 3.4 8.2 13.0 3.5 8.1 2.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB NHL PF01436.21 KFP12603.1 - 4.9e-52 171.5 19.8 8.9e-10 38.1 0.2 6.6 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 KFP12603.1 - 1.2e-19 70.6 8.7 1.2e-08 34.5 0.4 4.1 2 2 1 3 3 3 3 6-bladed beta-propeller Filamin PF00630.19 KFP12603.1 - 1e-17 64.8 0.0 3.9e-17 63.0 0.0 2.1 2 0 0 2 2 1 1 Filamin/ABP280 repeat SGL PF08450.12 KFP12603.1 - 6.4e-12 45.6 3.4 0.00011 21.9 0.1 5.6 1 1 4 6 6 6 3 SMP-30/Gluconolactonase/LRE-like region zf-B_box PF00643.24 KFP12603.1 - 9.3e-11 41.7 3.3 9.3e-11 41.7 3.3 2.9 3 1 0 3 3 1 1 B-box zinc finger zf-RING_UBOX PF13445.6 KFP12603.1 - 5.9e-10 39.0 5.8 5.9e-10 39.0 5.8 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP12603.1 - 2e-08 33.9 10.0 2e-08 33.9 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP12603.1 - 5.1e-08 32.6 10.2 5.1e-08 32.6 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP12603.1 - 1.2e-07 31.4 7.8 1.2e-07 31.4 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP12603.1 - 5.2e-07 29.5 8.5 5.2e-07 29.5 8.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP12603.1 - 7e-07 29.5 9.6 7e-07 29.5 9.6 2.7 2 0 0 2 2 2 1 Ring finger domain DUF4934 PF16288.5 KFP12603.1 - 1.7e-06 27.8 2.0 0.053 13.4 0.4 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4934) Prok-RING_4 PF14447.6 KFP12603.1 - 1.5e-05 24.7 8.8 1.5e-05 24.7 8.8 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP12603.1 - 0.0001 22.4 11.1 0.0001 22.4 11.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KFP12603.1 - 0.0066 16.5 1.4 0.017 15.2 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SBBP PF06739.11 KFP12603.1 - 0.0076 16.2 1.7 0.5 10.4 0.3 3.4 4 0 0 4 4 3 1 Beta-propeller repeat Caskin-tail PF16632.5 KFP12603.1 - 0.011 16.2 0.5 0.024 15.0 0.5 1.6 1 0 0 1 1 1 0 C-terminal region of Caskin Invasin_D3 PF09134.10 KFP12603.1 - 0.013 15.7 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Invasin, domain 3 Ldl_recept_b PF00058.17 KFP12603.1 - 0.026 15.0 0.0 28 5.3 0.0 3.9 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B zf-RING_11 PF17123.5 KFP12603.1 - 0.032 14.0 3.9 0.089 12.6 3.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger Cadherin_5 PF17892.1 KFP12603.1 - 0.22 11.5 0.9 0.48 10.4 0.0 2.1 2 0 0 2 2 1 0 Cadherin-like domain NPV_P10 PF05531.12 KFP12603.1 - 0.8 10.2 2.9 1.5 9.3 1.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein VCBS PF13517.6 KFP12603.1 - 3 8.5 9.0 27 5.4 0.1 4.5 2 1 3 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_10 PF16685.5 KFP12603.1 - 3.2 8.0 11.7 4.4 7.5 4.7 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 FH2 PF02181.23 KFP12605.1 - 1.1e-92 311.0 9.2 1.6e-92 310.5 9.2 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Arfaptin PF06456.13 KFP12606.1 - 8.1e-81 270.9 10.3 1.1e-80 270.5 10.3 1.1 1 0 0 1 1 1 1 Arfaptin-like domain TPR_MLP1_2 PF07926.12 KFP12606.1 - 0.039 14.0 5.5 2.5 8.2 1.0 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 KFP12606.1 - 3.6 7.7 12.2 0.34 11.0 1.1 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 KFP12606.1 - 8.3 6.9 9.7 13 6.4 2.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DDE_1 PF03184.19 KFP12607.1 - 3.2e-36 124.6 0.1 5e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFP12607.1 - 1.8e-18 66.3 0.0 3.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KFP12607.1 - 4.7e-11 42.1 2.2 8.6e-11 41.3 2.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_3 PF13358.6 KFP12607.1 - 0.0045 16.8 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 KFP12607.1 - 0.0062 16.3 0.0 0.079 12.8 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KFP12607.1 - 0.062 13.6 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Transposase CENP-B_dimeris PF09026.10 KFP12607.1 - 0.11 12.9 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PAF-AH_p_II PF03403.13 KFP12607.1 - 0.14 10.7 0.1 0.25 9.8 0.1 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II UPF0122 PF04297.14 KFP12607.1 - 0.14 12.4 0.2 0.31 11.3 0.2 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TMEM154 PF15102.6 KFP12608.1 - 3.3e-39 134.0 2.9 4e-39 133.8 2.9 1.1 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 KFP12608.1 - 0.0032 17.7 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) CcmH PF03918.14 KFP12608.1 - 0.005 16.1 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF3377 PF11857.8 KFP12608.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) CD34_antigen PF06365.12 KFP12608.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family RIFIN PF02009.16 KFP12608.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Rifin DUF4448 PF14610.6 KFP12608.1 - 0.023 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 KFP12608.1 - 0.026 15.4 0.0 0.032 15.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 KFP12608.1 - 0.033 14.2 0.5 0.055 13.6 0.5 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SIT PF15330.6 KFP12608.1 - 0.038 14.5 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF5305 PF17231.2 KFP12608.1 - 0.054 12.9 0.5 0.078 12.4 0.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4010 PF13194.6 KFP12608.1 - 0.058 13.1 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) ODV-E18 PF10717.9 KFP12608.1 - 0.062 13.2 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.9 KFP12608.1 - 0.066 12.0 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ac76 PF05814.11 KFP12608.1 - 0.072 13.1 0.5 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) DUF5385 PF17359.2 KFP12608.1 - 0.078 12.5 0.3 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5385) RseC_MucC PF04246.12 KFP12608.1 - 0.18 11.8 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SH3_1 PF00018.28 KFP12612.1 - 1.4e-57 191.1 2.2 1.2e-15 56.8 0.0 4.5 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 KFP12612.1 - 7.5e-51 169.8 1.5 2.9e-13 49.4 0.0 5.8 6 0 0 6 6 6 5 Variant SH3 domain SH3_2 PF07653.17 KFP12612.1 - 9.8e-39 130.8 1.2 1.1e-07 31.5 0.0 5.5 5 0 0 5 5 5 4 Variant SH3 domain TUDOR PF00567.24 KFP12612.1 - 0.0036 17.3 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Tudor domain DUF5348 PF17295.2 KFP12612.1 - 0.0054 16.6 2.7 1.1 9.2 0.1 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF5348) DUF3850 PF12961.7 KFP12612.1 - 0.028 14.5 0.3 4.8 7.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3850) Ribosomal_S3Ae PF01015.18 KFP12613.1 - 1.5e-99 331.6 7.0 1.8e-99 331.4 7.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KFP12613.1 - 0.0048 16.5 0.2 0.026 14.1 0.1 2.2 1 1 1 2 2 2 1 Partial alpha/beta-hydrolase lipase region NLRC4_HD2 PF17776.1 KFP12613.1 - 0.01 16.4 0.2 0.014 15.9 0.2 1.2 1 0 0 1 1 1 0 NLRC4 helical domain HD2 RnaseA PF00074.20 KFP12614.1 - 0.0018 18.7 0.0 0.0021 18.5 0.0 1.1 1 0 0 1 1 1 1 Pancreatic ribonuclease MBOAT PF03062.19 KFP12615.1 - 4.4e-12 46.0 10.1 2.3e-10 40.4 4.8 2.4 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family TFIIIC_delta PF12657.7 KFP12615.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term PMP22_Claudin PF00822.20 KFP12617.1 - 9.8e-17 61.3 0.3 1.3e-16 61.0 0.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFP12617.1 - 0.00083 19.6 2.7 0.0012 19.1 2.7 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF1282 PF06930.12 KFP12617.1 - 0.006 16.4 0.1 0.006 16.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1282) Clc-like PF07062.12 KFP12617.1 - 0.022 14.2 0.5 0.056 12.9 0.1 1.8 2 0 0 2 2 2 0 Clc-like Claudin_2 PF13903.6 KFP12617.1 - 0.036 13.8 14.8 0.068 12.9 10.6 2.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.15 KFP12617.1 - 0.87 10.1 8.2 3.4 8.2 2.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Ldl_recept_a PF00057.18 KFP12618.1 - 1.4e-50 169.2 90.1 1.9e-10 40.8 5.4 7.0 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFP12618.1 - 5.9e-19 68.3 6.1 2e-09 37.8 0.0 5.9 5 1 0 5 5 5 3 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP12618.1 - 1e-12 48.1 24.5 3.6e-08 33.5 6.9 7.3 5 1 1 6 6 6 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP12618.1 - 2.1e-09 37.1 7.2 2.4e-06 27.4 0.4 4.6 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP12618.1 - 3.7e-07 30.3 2.8 3.7e-07 30.3 2.8 7.8 4 2 3 7 7 7 1 Calcium-binding EGF domain CBM_21 PF03370.13 KFP12619.1 - 9.4e-32 109.5 0.3 1.6e-31 108.8 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP12619.1 - 1.2e-12 48.2 0.2 2.4e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) RNase_T PF00929.24 KFP12620.1 - 1.4e-29 103.8 0.0 3.1e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 Exonuclease SAP PF02037.27 KFP12620.1 - 6e-08 32.3 0.7 1.2e-07 31.3 0.7 1.5 1 0 0 1 1 1 1 SAP domain LRR_8 PF13855.6 KFP12621.1 - 3e-15 55.7 8.2 2.4e-08 33.6 0.7 2.9 3 0 0 3 3 3 2 Leucine rich repeat COR PF16095.5 KFP12621.1 - 1.9e-13 50.6 0.0 5.9e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 KFP12621.1 - 8.4e-13 48.3 17.0 9.7e-07 29.0 1.8 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Roc PF08477.13 KFP12621.1 - 4.9e-05 23.5 0.0 0.0043 17.2 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_9 PF14580.6 KFP12621.1 - 0.00032 20.3 2.0 0.053 13.0 0.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP12621.1 - 0.00053 20.2 10.2 0.85 10.4 0.8 5.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP12621.1 - 0.11 12.6 2.6 37 4.7 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KFP12621.1 - 0.14 12.3 0.1 17 5.5 0.0 2.8 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain Ank_5 PF13857.6 KFP12622.1 - 4.2e-106 345.6 41.3 4.2e-13 49.2 0.3 14.4 6 5 9 15 15 15 13 Ankyrin repeats (many copies) Ank PF00023.30 KFP12622.1 - 2.1e-102 331.5 49.6 8.9e-08 32.2 0.1 17.6 17 0 0 17 17 17 15 Ankyrin repeat Ank_2 PF12796.7 KFP12622.1 - 2.9e-99 325.8 30.2 7.6e-15 55.3 0.2 10.4 5 2 5 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP12622.1 - 5.5e-98 320.2 40.9 3.3e-13 49.9 0.2 14.5 8 6 9 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP12622.1 - 2.7e-86 273.1 30.9 7.8e-07 28.9 0.1 18.0 19 0 0 19 19 19 14 Ankyrin repeat PARP PF00644.20 KFP12622.1 - 6.8e-27 94.3 4.8 1.6e-24 86.6 4.8 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFP12622.1 - 8.5e-15 54.6 0.4 1.9e-14 53.5 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP12622.1 - 3.1e-12 46.8 0.6 7e-12 45.6 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vps39_1 PF10366.9 KFP12622.1 - 0.047 14.0 3.1 15 5.9 0.1 4.3 5 0 0 5 5 5 0 Vacuolar sorting protein 39 domain 1 DSPc PF00782.20 KFP12623.1 - 3.8e-38 130.3 0.3 5.2e-38 129.9 0.3 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP12623.1 - 4.7e-06 26.3 0.1 6.1e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KFP12623.1 - 0.045 13.4 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KFP12623.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1610 PF07754.11 KFP12623.1 - 0.49 10.4 0.2 0.49 10.4 0.2 2.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1610) Kazal_1 PF00050.21 KFP12624.1 - 3.1e-14 52.7 4.8 3.3e-14 52.6 4.8 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP12624.1 - 3.3e-10 39.9 2.8 3.9e-10 39.7 2.8 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Homeodomain PF00046.29 KFP12625.1 - 1.5e-09 37.5 0.1 1.8e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Colicin_Pyocin PF01320.18 KFP12625.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein GlgS PF08971.11 KFP12625.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthesis protein Homez PF11569.8 KFP12625.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Arf PF00025.21 KFP12626.1 - 4.6e-38 130.4 0.0 5.1e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP12626.1 - 2e-12 46.9 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP12626.1 - 2.1e-10 40.9 0.0 3.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP12626.1 - 2.1e-09 37.2 0.0 2.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP12626.1 - 1e-05 25.0 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP12626.1 - 0.00059 19.1 0.1 0.03 13.5 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 KFP12626.1 - 0.001 19.3 0.2 0.0081 16.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFP12626.1 - 0.0012 18.9 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP12626.1 - 0.0033 17.8 0.1 0.0063 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFP12626.1 - 0.015 15.7 0.1 0.067 13.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP12626.1 - 0.045 14.3 0.1 0.064 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KFP12626.1 - 0.051 13.4 0.2 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KFP12626.1 - 0.066 12.8 0.1 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 KFP12626.1 - 0.084 12.5 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 KFP12626.1 - 0.087 12.6 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) NACHT PF05729.12 KFP12626.1 - 0.15 12.0 0.6 1.8 8.5 0.6 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFP12626.1 - 0.15 12.6 0.1 0.34 11.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter SRP72 PF08492.12 KFP12627.1 - 2.6e-22 79.0 10.3 2.6e-22 79.0 10.3 3.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 KFP12627.1 - 1.1e-20 73.8 3.4 1.1e-20 73.8 3.4 3.3 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_2 PF07719.17 KFP12627.1 - 3.2e-15 54.9 15.7 0.0063 16.5 0.0 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP12627.1 - 3.5e-15 56.3 13.5 0.0045 17.5 0.1 7.1 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP12627.1 - 1.4e-13 50.4 4.8 0.38 11.7 0.0 7.7 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP12627.1 - 9.5e-11 41.0 9.9 0.026 14.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP12627.1 - 1.5e-09 38.0 21.4 8.9e-05 22.6 2.6 6.4 4 3 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFP12627.1 - 3.6e-08 33.0 13.3 0.14 12.4 0.9 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP12627.1 - 3.3e-07 30.5 22.7 0.00024 21.3 0.9 6.9 7 3 1 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP12627.1 - 1.6e-06 28.4 19.8 0.51 11.1 0.1 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat BTAD PF03704.17 KFP12627.1 - 6.6e-06 26.6 8.8 0.054 13.9 0.3 4.8 4 2 0 4 4 4 2 Bacterial transcriptional activator domain TPR_11 PF13414.6 KFP12627.1 - 1.9e-05 24.2 11.3 0.18 11.5 0.0 5.9 7 0 0 7 7 6 2 TPR repeat TPR_16 PF13432.6 KFP12627.1 - 9.8e-05 22.9 1.8 14 6.5 0.4 6.4 6 1 2 8 8 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFP12627.1 - 0.00018 21.1 5.2 0.006 16.2 0.5 4.7 5 2 0 6 6 6 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 KFP12627.1 - 0.00024 21.2 2.3 1.7 8.8 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 KFP12627.1 - 0.00044 20.3 0.1 25 5.4 0.0 5.3 6 0 0 6 6 5 0 PPR repeat TPR_7 PF13176.6 KFP12627.1 - 0.00065 19.5 6.3 32 4.9 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat CorA PF01544.18 KFP12627.1 - 0.018 14.4 0.4 0.049 12.9 0.4 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PMEI PF04043.15 KFP12627.1 - 0.034 14.5 9.0 0.13 12.6 0.5 3.8 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor ATP13 PF12921.7 KFP12627.1 - 0.04 13.8 0.2 3.4 7.6 0.0 3.3 2 1 1 3 3 3 0 Mitochondrial ATPase expression PPR_2 PF13041.6 KFP12627.1 - 0.05 13.8 0.2 87 3.4 0.0 4.5 5 0 0 5 5 4 0 PPR repeat family HemY_N PF07219.13 KFP12627.1 - 0.11 12.8 4.5 33 4.7 0.0 4.5 4 0 0 4 4 4 0 HemY protein N-terminus DUF4919 PF16266.5 KFP12627.1 - 0.11 12.5 3.5 0.51 10.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) TPR_17 PF13431.6 KFP12627.1 - 0.17 12.4 1.9 2.1e+02 2.6 0.0 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat ASL_C PF08328.11 KFP12627.1 - 0.57 10.3 4.6 17 5.5 0.1 4.1 3 2 1 4 4 4 0 Adenylosuccinate lyase C-terminal TPR_10 PF13374.6 KFP12627.1 - 0.97 9.4 5.9 36 4.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC-167 PF15188.6 KFP12627.1 - 9.9 6.6 8.0 0.64 10.4 0.5 2.8 4 0 0 4 4 3 0 Coiled-coil domain-containing protein 167 Vps55 PF04133.14 KFP12628.1 - 6e-40 135.8 6.2 6.8e-40 135.7 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 KFP12628.1 - 0.061 13.8 0.4 0.11 12.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) YwiC PF14256.6 KFP12628.1 - 0.065 13.6 6.3 0.14 12.5 6.3 1.5 1 1 0 1 1 1 0 YwiC-like protein SARAF PF06682.12 KFP12629.1 - 4.2e-84 283.0 1.0 4.8e-84 282.9 1.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis UPF0114 PF03350.16 KFP12629.1 - 0.038 14.2 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 zf-H2C2_2 PF13465.6 KFP12630.1 - 2.7e-29 100.2 67.4 3.4e-08 33.5 1.3 11.3 11 1 0 11 11 11 7 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP12630.1 - 8.1e-28 95.8 64.1 1.4e-06 28.0 4.3 8.7 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP12630.1 - 3.2e-18 65.1 78.7 0.00037 20.8 4.0 9.7 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP12630.1 - 6.4e-12 45.2 72.4 0.049 14.5 0.8 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP12630.1 - 0.013 15.8 0.9 0.013 15.8 0.9 7.4 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP12630.1 - 1 9.8 42.6 0.74 10.2 8.0 6.1 2 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpb2_6 PF00562.28 KFP12631.1 - 2.5e-128 428.5 0.2 3.6e-128 427.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFP12631.1 - 3e-68 229.3 0.1 6.6e-68 228.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFP12631.1 - 3e-56 190.1 0.0 8.9e-56 188.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KFP12631.1 - 4e-34 116.9 1.5 7.6e-34 116.0 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KFP12631.1 - 3e-24 85.1 0.8 7.6e-24 83.8 0.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFP12631.1 - 6.4e-24 83.9 0.0 1.6e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFP12631.1 - 7.8e-19 68.0 0.5 1.9e-18 66.7 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Amidoligase_2 PF12224.8 KFP12631.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme HECT PF00632.25 KFP12632.1 - 3.1e-35 122.2 0.0 3.4e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 KFP12633.1 - 5.1e-85 279.9 31.0 4.6e-14 52.8 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KFP12633.1 - 1.1e-81 274.7 0.4 1.6e-81 274.2 0.4 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 KFP12633.1 - 5e-48 160.0 42.9 5.6e-10 38.8 0.1 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KFP12633.1 - 0.058 13.2 0.1 0.73 9.7 0.0 2.8 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain RhoGAP PF00620.27 KFP12634.1 - 9e-45 152.2 0.5 5.8e-44 149.6 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain DUF4314 PF14192.6 KFP12634.1 - 0.13 12.2 0.6 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) DUF1192 PF06698.11 KFP12634.1 - 3.3 7.8 6.2 33 4.6 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HBM PF16591.5 KFP12634.1 - 4.1 6.7 11.0 0.46 9.9 0.4 3.2 3 0 0 3 3 3 0 Helical bimodular sensor domain Dsh_C PF12316.8 KFP12634.1 - 4.1 7.7 8.8 12 6.2 8.8 1.7 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Synuclein PF01387.17 KFP12636.1 - 1.2e-55 187.4 17.3 1.4e-55 187.1 17.3 1.0 1 0 0 1 1 1 1 Synuclein C1q PF00386.21 KFP12639.1 - 1.3e-25 90.0 0.2 1.5e-24 86.6 0.0 2.9 2 0 0 2 2 2 1 C1q domain EMI PF07546.13 KFP12639.1 - 1.8e-12 47.8 3.1 1.8e-12 47.8 3.1 2.1 2 0 0 2 2 2 1 EMI domain EGF PF00008.27 KFP12639.1 - 9.2e-06 25.9 7.2 9.2e-06 25.9 7.2 1.7 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 KFP12639.1 - 0.014 16.0 5.7 0.038 14.6 5.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF BclA_C PF18573.1 KFP12639.1 - 0.065 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 BclA C-terminal domain Topo-VIb_trans PF09239.11 KFP12639.1 - 0.068 13.0 0.8 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer FOP_dimer PF09398.10 KFP12639.1 - 0.12 12.6 2.1 0.9 9.8 0.8 2.8 2 0 0 2 2 2 0 FOP N terminal dimerisation domain EGF_CA PF07645.15 KFP12639.1 - 0.13 12.5 6.1 0.48 10.7 6.1 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain Laminin_II PF06009.12 KFP12639.1 - 0.42 10.6 43.5 0.16 12.0 0.6 7.8 5 3 3 8 8 8 0 Laminin Domain II Baculo_PEP_C PF04513.12 KFP12639.1 - 0.46 10.5 42.9 0.031 14.3 1.9 6.6 4 3 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus ANF_receptor PF01094.28 KFP12643.1 - 0.0039 16.4 0.0 0.0039 16.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region COE1_DBD PF16422.5 KFP12658.1 - 7.9e-111 369.1 4.9 2.6e-108 360.8 4.7 2.2 1 1 1 2 2 2 2 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 KFP12658.1 - 1.1e-35 121.1 3.0 5e-29 99.7 0.4 2.4 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 KFP12658.1 - 9.8e-13 48.0 0.1 9.8e-13 48.0 0.1 2.0 3 0 0 3 3 3 1 IPT/TIG domain DNA_binding_1 PF01035.20 KFP12659.1 - 1.4e-26 92.4 0.0 1.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KFP12659.1 - 0.16 12.8 0.1 0.25 12.2 0.1 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain KI67R PF08065.12 KFP12662.1 - 1e-21 77.6 9.7 2.6e-09 37.6 0.5 2.9 1 1 2 3 3 3 3 KI67R (NUC007) repeat HTH_49 PF18010.1 KFP12662.1 - 3e-05 23.7 0.3 54 3.8 0.0 5.1 5 0 0 5 5 5 0 Cry35Ab1 HTH C-terminal domain Sybindin PF04099.12 KFP12662.1 - 0.0017 18.3 0.0 0.25 11.3 0.0 2.3 1 1 0 1 1 1 1 Sybindin-like family PI_PP_C PF18365.1 KFP12662.1 - 0.039 13.9 0.4 9.1 6.3 0.1 2.4 1 1 1 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Clusterin PF01093.17 KFP12662.1 - 0.11 11.5 0.6 0.17 10.9 0.4 1.4 1 1 1 2 2 2 0 Clusterin APC1_C PF18122.1 KFP12663.1 - 0.00015 21.7 3.1 3.8 7.4 0.0 4.5 1 1 1 2 2 2 2 Anaphase-promoting complex sub unit 1 C-terminal domain CHS5_N PF16892.5 KFP12663.1 - 0.00044 20.2 0.0 54 3.8 0.0 4.9 4 1 1 5 5 5 0 Chitin biosynthesis protein CHS5 N-terminus DUF5568 PF17724.1 KFP12663.1 - 0.0043 16.9 8.6 2 8.2 0.3 3.4 1 1 4 5 5 5 5 Family of unknown function (DUF5568) Chromadorea_ALT PF05535.12 KFP12663.1 - 0.016 15.4 2.7 5.7 7.2 0.1 3.1 1 1 3 4 4 4 0 Chromadorea ALT protein Prim_Zn_Ribbon PF08273.12 KFP12663.1 - 0.21 11.9 8.8 1.3e+02 3.0 0.0 5.5 6 0 0 6 6 6 0 Zinc-binding domain of primase-helicase DAN PF03045.15 KFP12663.1 - 1.3 9.1 13.1 26 4.9 2.0 4.2 1 1 2 3 3 3 0 DAN domain Herpes_US9 PF06072.11 KFP12663.1 - 1.7 8.6 9.2 3.4 7.6 0.7 3.1 2 1 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Romo1 PF10247.9 KFP12663.1 - 3.9 7.9 14.5 21 5.6 0.5 3.7 2 2 2 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 FAM35_C PF15793.5 KFP12664.1 - 0.18 11.2 0.1 0.31 10.4 0.0 1.4 2 0 0 2 2 2 0 Protein family FAM35, C-terminal PP1_bind PF15276.6 KFP12665.1 - 5.8e-23 81.0 0.8 7.5e-23 80.6 0.8 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 binding FHA PF00498.26 KFP12666.1 - 6e-13 48.9 0.0 8.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP12666.1 - 1.6e-09 37.9 0.0 2.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KFP12666.1 - 0.00085 19.5 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 FHA domain CD34_antigen PF06365.12 KFP12668.1 - 0.13 11.9 0.4 0.8 9.2 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF4179 PF13786.6 KFP12668.1 - 0.34 11.4 2.7 9.6 6.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF2207 PF09972.9 KFP12668.1 - 0.69 8.6 7.1 0.16 10.7 3.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF898 PF05987.13 KFP12668.1 - 2.5 7.1 9.6 8.8 5.3 9.6 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) zf-LITAF-like PF10601.9 KFP12668.1 - 6.9 7.0 7.5 64 3.9 0.7 3.6 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Neuropeptide_S PF14993.6 KFP12670.1 - 1.2e-34 118.0 0.6 1.2e-34 117.9 0.6 1.0 1 0 0 1 1 1 1 Neuropeptide S precursor protein DHR-2 PF06920.13 KFP12671.1 - 2.4e-81 274.0 3.8 2.9e-81 273.7 3.8 1.1 1 0 0 1 1 1 1 Dock homology region 2 SR-25 PF10500.9 KFP12671.1 - 0.033 13.8 10.3 0.054 13.1 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM196 PF15265.6 KFP12673.1 - 4.3e-192 640.0 25.3 2.2e-116 390.3 11.3 2.0 1 1 1 2 2 2 2 FAM196 family CX PF01705.19 KFP12673.1 - 0.14 12.8 0.9 11 6.6 0.0 2.7 2 0 0 2 2 2 0 CX module Flu_C_NS2 PF03555.14 KFP12674.1 - 0.16 12.1 0.2 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) DOCK-C2 PF14429.6 KFP12675.1 - 2.4e-38 131.9 0.0 3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFP12675.1 - 4.5e-14 52.2 0.0 6.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus Centro_C10orf90 PF17730.1 KFP12678.1 - 2e-236 785.8 21.9 2.5e-236 785.5 21.9 1.1 1 0 0 1 1 1 1 Centrosomal C10orf90 ALMS_motif PF15309.6 KFP12678.1 - 9.7e-16 58.5 1.4 9.7e-16 58.5 1.4 2.4 1 1 1 2 2 2 1 ALMS motif Reprolysin PF01421.19 KFP12679.1 - 1.4e-73 247.1 0.0 1.4e-73 247.1 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP12679.1 - 4.4e-33 114.1 4.3 4.4e-33 114.1 4.3 3.4 3 1 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP12679.1 - 1.8e-28 99.5 0.2 4e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFP12679.1 - 4.4e-21 75.9 0.0 1.1e-20 74.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFP12679.1 - 7.2e-19 68.4 27.6 7.2e-19 68.4 27.6 4.3 3 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KFP12679.1 - 1.4e-14 54.7 0.0 2.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP12679.1 - 2.2e-14 53.6 0.0 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP12679.1 - 2.2e-13 50.6 0.0 3.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFP12679.1 - 0.062 12.2 0.2 0.1 11.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Zincin_1 PF06262.11 KFP12679.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase APH PF01636.23 KFP12680.1 - 8e-39 134.0 0.1 1.2e-38 133.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.6 KFP12680.1 - 2e-10 41.0 0.0 6e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP12680.1 - 1.9e-07 31.6 0.0 3.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kdo PF06293.14 KFP12680.1 - 0.0015 17.9 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KFP12680.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFP12680.1 - 0.013 15.1 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family BRAP2 PF07576.12 KFP12681.1 - 5.1e-36 122.9 0.8 1.1e-35 121.8 0.8 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KFP12681.1 - 2.9e-20 72.3 8.8 2.9e-20 72.3 8.8 2.3 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KFP12681.1 - 1.3e-08 35.0 7.0 1.3e-08 35.0 7.0 2.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP12681.1 - 8e-08 32.0 6.1 8e-08 32.0 6.1 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP12681.1 - 7.1e-06 26.2 4.7 7.1e-06 26.2 4.7 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP12681.1 - 9.7e-06 25.2 1.8 9.7e-06 25.2 1.8 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFP12681.1 - 2.2e-05 24.3 5.7 2.2e-05 24.3 5.7 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP12681.1 - 2.7e-05 24.1 0.3 2.7e-05 24.1 0.3 2.9 1 1 1 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP12681.1 - 6.3e-05 22.8 6.2 6.3e-05 22.8 6.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFP12681.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ANAPC11 PF12861.7 KFP12681.1 - 0.0041 17.1 3.0 0.016 15.3 3.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFP12681.1 - 0.0043 16.9 18.3 0.027 14.3 7.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) KASH_CCD PF14662.6 KFP12681.1 - 0.0049 16.7 26.2 0.0089 15.9 26.2 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-C3H2C3 PF17122.5 KFP12681.1 - 0.031 14.3 4.2 0.15 12.1 4.2 2.4 1 0 0 1 1 1 0 Zinc-finger FXMRP1_C_core PF12235.8 KFP12681.1 - 0.082 13.5 0.6 0.082 13.5 0.6 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Zn_ribbon_17 PF17120.5 KFP12681.1 - 0.15 11.7 15.3 0.18 11.4 5.6 2.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF2935 PF11155.8 KFP12681.1 - 0.17 12.2 4.2 0.22 11.9 2.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) FapA PF03961.13 KFP12681.1 - 0.17 10.4 14.6 0.25 9.9 14.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vac_Fusion PF02346.16 KFP12681.1 - 0.19 11.3 3.7 0.8 9.4 0.8 2.9 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Atg14 PF10186.9 KFP12681.1 - 0.23 10.5 18.0 0.48 9.5 18.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_S46 PF10459.9 KFP12681.1 - 0.31 9.6 8.9 0.45 9.1 8.9 1.2 1 0 0 1 1 1 0 Peptidase S46 V_ATPase_I PF01496.19 KFP12681.1 - 0.31 8.9 17.9 0.79 7.6 13.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 KFP12681.1 - 0.42 9.1 0.9 0.59 8.6 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prok-RING_4 PF14447.6 KFP12681.1 - 0.59 10.0 18.1 0.21 11.5 7.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Baculo_PEP_C PF04513.12 KFP12681.1 - 0.87 9.6 11.7 0.14 12.2 6.5 2.2 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 KFP12681.1 - 0.92 9.6 24.2 1.7 8.7 24.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 KFP12681.1 - 1.1 9.8 8.8 7 7.2 5.6 3.3 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KFP12681.1 - 1.8 8.1 10.9 2.9 7.4 10.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF3_N PF09440.10 KFP12681.1 - 1.9 8.9 14.2 1.4 9.3 11.0 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain CREPT PF16566.5 KFP12681.1 - 2 8.6 19.8 1.2 9.3 11.9 3.1 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour KELK PF15796.5 KFP12681.1 - 3 8.4 21.4 1.7 9.2 6.2 3.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMPIT PF07851.13 KFP12681.1 - 3.2 6.9 12.9 5.6 6.1 12.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein GBP_C PF02841.14 KFP12681.1 - 5.3 6.3 25.5 0.082 12.3 18.2 1.6 2 0 0 2 2 1 0 Guanylate-binding protein, C-terminal domain Spc7 PF08317.11 KFP12681.1 - 9.4 5.0 28.6 0.41 9.5 14.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein SM-ATX PF14438.6 KFP12682.1 - 3.1e-21 75.3 0.1 8.1e-21 74.0 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.13 KFP12682.1 - 1.2e-15 57.8 4.9 3e-15 56.5 4.9 1.8 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 KFP12682.1 - 3.5e-06 26.3 1.0 3.5e-06 26.3 1.0 2.0 2 0 0 2 2 2 1 Ataxin-2 C-terminal region LSM PF01423.22 KFP12682.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 LSM domain Phe_ZIP PF08916.11 KFP12683.1 - 4.1e-21 75.4 5.2 7.7e-21 74.6 5.2 1.5 1 0 0 1 1 1 1 Phenylalanine zipper SH2 PF00017.24 KFP12683.1 - 8.9e-10 38.5 0.1 1.7e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 KFP12684.1 - 9.6e-21 74.3 0.0 1.4e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP12684.1 - 4.3e-06 26.9 0.0 6.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP12684.1 - 0.00042 20.7 1.0 0.037 14.5 1.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFP12684.1 - 0.0029 17.9 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFP12684.1 - 0.023 14.5 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 KFP12684.1 - 0.048 13.5 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CUT PF02376.15 KFP12685.1 - 1.4e-78 259.0 0.2 1.5e-25 89.1 0.0 3.4 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 KFP12685.1 - 4.8e-12 45.6 0.7 3.5e-11 42.8 0.3 2.7 2 0 0 2 2 2 1 Homeodomain HNF-1_N PF04814.13 KFP12685.1 - 2e-05 25.3 0.1 0.8 10.3 0.0 3.6 3 0 0 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox_KN PF05920.11 KFP12685.1 - 0.019 14.9 0.3 0.019 14.9 0.3 3.6 3 0 0 3 3 3 0 Homeobox KN domain DUF5572 PF17733.1 KFP12685.1 - 0.028 14.2 3.7 30 4.5 0.0 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5572) Phage_connect_1 PF05135.13 KFP12685.1 - 0.063 13.8 0.0 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein SlyX PF04102.12 KFP12685.1 - 0.097 13.3 3.7 1.5 9.5 1.7 3.1 2 0 0 2 2 2 0 SlyX EntA_Immun PF08951.10 KFP12685.1 - 0.11 12.9 0.3 15 6.1 0.0 3.3 3 0 0 3 3 3 0 Enterocin A Immunity Csm1_N PF18504.1 KFP12685.1 - 0.25 11.7 8.6 4.3 7.8 0.8 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 KFP12685.1 - 0.47 10.6 7.0 11 6.2 0.1 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation EF-hand_1 PF00036.32 KFP12686.1 - 2e-13 48.9 1.1 5.1e-06 25.7 0.9 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP12686.1 - 4.3e-09 35.6 1.4 2e-06 27.2 0.8 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KFP12686.1 - 1.6e-08 34.3 1.9 0.0024 17.7 0.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.6 KFP12686.1 - 7e-08 32.8 0.8 1.8e-05 25.1 0.7 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP12686.1 - 0.0017 17.7 1.0 0.0017 17.7 1.0 2.4 2 0 0 2 2 2 1 EF hand Caleosin PF05042.13 KFP12686.1 - 0.054 13.4 0.2 9.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein DUF488 PF04343.13 KFP12687.1 - 0.073 13.7 0.3 0.073 13.7 0.3 3.6 3 2 0 3 3 3 0 Protein of unknown function, DUF488 HP0268 PF18618.1 KFP12687.1 - 0.11 12.9 0.2 0.11 12.9 0.2 3.7 4 0 0 4 4 4 0 HP0268 PI_PP_I PF18363.1 KFP12687.1 - 0.89 9.8 8.6 0.86 9.8 1.2 2.9 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain FlaC_arch PF05377.11 KFP12687.1 - 4.7 7.7 21.7 0.083 13.3 1.0 4.9 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Metallophos PF00149.28 KFP12688.1 - 4.6e-41 141.6 0.1 5.7e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFP12688.1 - 5.1e-17 62.0 0.9 1.2e-16 60.9 0.5 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain VGPC1_C PF16799.5 KFP12689.1 - 4.5e-25 87.4 9.5 7.4e-25 86.7 9.5 1.4 1 0 0 1 1 1 1 C-terminal membrane-localisation domain of ion-channel, VCN1 Ion_trans PF00520.31 KFP12689.1 - 1.5e-06 27.6 6.4 2.2e-06 27.1 6.4 1.2 1 0 0 1 1 1 1 Ion transport protein PLDc_2 PF13091.6 KFP12689.1 - 0.03 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 PLD-like domain TMF_DNA_bd PF12329.8 KFP12689.1 - 0.21 11.6 6.0 0.4 10.7 6.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1619 PF07773.11 KFP12690.1 - 2.4e-83 280.7 7.1 4.7e-81 273.2 3.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) SpoIIE PF07228.12 KFP12691.1 - 9.7e-15 55.0 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFP12691.1 - 4.1e-06 26.6 0.8 4e-05 23.4 0.8 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFP12691.1 - 4.6e-05 23.2 0.2 0.0083 15.8 0.1 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C Metallophos_2 PF12850.7 KFP12692.1 - 4.9e-22 78.9 0.1 5.7e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFP12692.1 - 3.2e-05 24.5 1.3 0.12 12.8 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Rod_C PF10493.9 KFP12693.1 - 3.3e-259 860.9 9.1 3.3e-259 860.9 9.1 2.2 3 0 0 3 3 3 1 Rough deal protein C-terminal region MRP-S22 PF10245.9 KFP12693.1 - 0.0076 16.0 0.4 0.022 14.5 0.4 1.7 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 PSP PF04046.16 KFP12694.1 - 1.3e-17 63.4 0.2 2.8e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 KFP12694.1 - 3.1e-05 23.9 4.0 5.3e-05 23.1 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle CAP_GLY PF01302.25 KFP12695.1 - 8.8e-48 160.2 3.4 2.7e-24 85.0 0.5 2.3 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 KFP12695.1 - 7.2e-15 54.4 20.7 7.1e-09 35.3 4.3 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle Fungal_TACC PF12709.7 KFP12695.1 - 5.4e-05 23.6 6.1 5.4e-05 23.6 6.1 15.7 6 4 6 15 15 15 2 Fungal Transforming acidic coiled-coil (TACC) proteins zf-CCHC_4 PF14392.6 KFP12695.1 - 1.9 8.3 6.7 3.9 7.3 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle Sec1 PF00995.23 KFP12696.1 - 3.6e-117 393.0 0.0 4.1e-117 392.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1629 PF07791.11 KFP12696.1 - 0.041 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) Phage_HK97_TLTM PF06120.11 KFP12696.1 - 0.14 11.3 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Smac_DIABLO PF09057.10 KFP12697.1 - 7.6e-96 319.8 5.7 8.7e-96 319.6 5.7 1.0 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases LRR_9 PF14580.6 KFP12698.1 - 1.2e-09 38.0 0.1 1.8e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFP12698.1 - 8.1e-08 31.9 13.6 0.028 14.2 0.0 4.1 3 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP12698.1 - 3.8e-06 27.1 17.7 0.0047 17.3 0.3 4.2 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP12698.1 - 0.00061 19.6 5.7 1.4 9.1 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 KFP12698.1 - 0.005 17.2 10.7 10 7.1 0.4 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat HLH PF00010.26 KFP12699.1 - 4.1e-07 29.9 0.6 4.1e-07 29.9 0.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 KFP12699.1 - 0.0029 18.0 1.9 0.0073 16.7 1.9 1.6 1 0 0 1 1 1 1 Cell division protein ZapB ATG16 PF08614.11 KFP12699.1 - 0.0074 16.5 1.8 0.014 15.6 1.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HMMR_C PF15908.5 KFP12699.1 - 0.0091 16.3 0.6 0.019 15.2 0.6 1.5 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal DivIC PF04977.15 KFP12699.1 - 0.017 14.9 1.1 0.033 13.9 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Troponin PF00992.20 KFP12699.1 - 0.03 14.6 0.7 0.054 13.8 0.7 1.4 1 0 0 1 1 1 0 Troponin DUF4416 PF14385.6 KFP12699.1 - 0.06 13.3 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) RNA_pol_Rpb1_6 PF04992.14 KFP12699.1 - 0.077 12.8 0.7 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 RasGAP_C PF03836.15 KFP12699.1 - 0.079 13.1 0.9 0.17 12.0 0.9 1.6 1 0 0 1 1 1 0 RasGAP C-terminus Seryl_tRNA_N PF02403.22 KFP12699.1 - 0.11 12.7 2.1 0.22 11.7 2.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TolA_bind_tri PF16331.5 KFP12699.1 - 0.14 12.2 3.5 0.27 11.3 3.5 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation bZIP_1 PF00170.21 KFP12699.1 - 0.54 10.4 3.3 1.1 9.4 3.0 1.7 1 1 0 1 1 1 0 bZIP transcription factor BCL_N PF04714.13 KFP12700.1 - 1.7e-10 40.8 1.7 4.4e-10 39.5 1.7 1.7 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Defensin_propep PF00879.18 KFP12700.1 - 0.14 12.4 2.2 0.35 11.2 2.2 1.7 1 0 0 1 1 1 0 Defensin propeptide WD40 PF00400.32 KFP12701.1 - 8.3e-25 86.6 11.8 0.00058 20.6 0.2 9.3 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP12701.1 - 1.7e-05 25.0 0.0 0.023 15.0 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP12701.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain UPF0154 PF03672.13 KFP12701.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PDZ_2 PF13180.6 KFP12702.1 - 2.9e-10 40.3 0.1 4e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP12702.1 - 4.7e-08 32.8 0.2 8e-08 32.0 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP12702.1 - 8e-07 29.3 0.2 1.2e-06 28.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain Nas2_N PF18265.1 KFP12702.1 - 4.4e-05 23.3 1.0 9.5e-05 22.2 1.0 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 KFP12702.1 - 0.0001 22.7 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain RdgC PF04381.12 KFP12702.1 - 0.18 11.1 1.9 0.2 10.9 1.2 1.3 2 0 0 2 2 2 0 Putative exonuclease, RdgC Glyoxalase PF00903.25 KFP12703.1 - 1.2e-20 74.0 0.6 1.1e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFP12703.1 - 5.4e-11 42.7 0.1 0.00017 21.8 0.1 3.0 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFP12703.1 - 0.00025 21.2 0.0 0.46 10.6 0.0 2.6 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KFP12703.1 - 0.0018 18.5 0.1 0.0053 16.9 0.1 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ras PF00071.22 KFP12704.1 - 1.4e-38 132.1 0.1 1.6e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP12704.1 - 6.2e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP12704.1 - 0.00081 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP12704.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain KR PF08659.10 KFP12704.1 - 0.039 13.9 0.1 0.77 9.6 0.2 2.0 1 1 1 2 2 2 0 KR domain TMPIT PF07851.13 KFP12705.1 - 3.4e-150 499.7 16.5 3.9e-150 499.5 16.5 1.0 1 0 0 1 1 1 1 TMPIT-like protein Snapin_Pallidin PF14712.6 KFP12705.1 - 0.99 9.9 5.3 8 7.0 1.9 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Sugar_tr PF00083.24 KFP12706.1 - 1.2e-20 73.9 4.0 2.4e-20 72.8 4.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP12706.1 - 0.00016 20.7 12.3 0.0043 16.0 10.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 KFP12706.1 - 1.2 9.3 11.6 2.4 8.3 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 KFP12707.1 - 5.6e-49 167.2 0.6 6.6e-49 167.0 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP12707.1 - 4.7e-20 71.8 3.9 6.2e-20 71.4 3.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DER1 PF04511.15 KFP12708.1 - 1.6e-66 223.9 13.2 1.8e-66 223.7 13.2 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 KFP12708.1 - 0.18 11.6 2.4 0.31 10.8 0.0 2.1 1 1 1 2 2 2 0 Oleosin SNF5 PF04855.12 KFP12709.1 - 9.6e-57 192.5 0.7 9.1e-30 104.2 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.11 KFP12709.1 - 0.0038 16.1 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) V-set PF07686.17 KFP12710.1 - 2.7e-19 69.3 0.0 3.1e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12710.1 - 3e-08 34.2 0.1 5.6e-08 33.3 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP12710.1 - 3.8e-06 27.0 0.0 1.6e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12710.1 - 8.3e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP12710.1 - 3.7e-05 24.0 0.4 0.00014 22.1 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP12710.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Metallophos_2 PF12850.7 KFP12711.1 - 4.3e-21 75.8 0.0 5.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFP12711.1 - 3.5e-05 24.4 0.5 0.012 16.1 0.5 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase V-set PF07686.17 KFP12712.1 - 7.1e-15 55.1 0.1 7.7e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12712.1 - 1.9e-07 31.6 0.9 6.2e-07 29.9 0.9 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12712.1 - 0.00014 21.9 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12712.1 - 0.0029 17.7 0.2 0.013 15.6 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain BACON PF13004.7 KFP12712.1 - 0.7 9.9 3.9 44 4.2 0.4 3.0 2 1 0 2 2 2 0 Putative binding domain, N-terminal V-set PF07686.17 KFP12713.1 - 1.6e-14 54.0 0.1 1.7e-14 53.9 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12713.1 - 1.3e-06 28.9 0.5 4e-06 27.3 0.5 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12713.1 - 0.00018 21.5 0.0 0.0028 17.7 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12713.1 - 0.0014 18.7 0.1 0.0028 17.8 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP12714.1 - 1.2e-14 54.4 0.1 1.3e-14 54.3 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12714.1 - 9.2e-08 32.6 0.3 1.8e-07 31.6 0.3 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12714.1 - 2.4e-05 24.3 0.0 0.00026 21.0 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12714.1 - 0.004 17.3 0.1 0.016 15.4 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12714.1 - 0.045 14.1 0.2 0.077 13.3 0.2 1.5 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP12715.1 - 8.6e-15 54.8 0.1 9.4e-15 54.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12715.1 - 4.4e-07 30.4 0.8 1.4e-06 28.8 0.8 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12715.1 - 0.00035 20.6 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12715.1 - 0.0011 19.1 0.3 0.0051 17.0 0.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain BACON PF13004.7 KFP12715.1 - 0.83 9.7 3.7 63 3.7 0.1 3.0 2 1 1 3 3 3 0 Putative binding domain, N-terminal V-set PF07686.17 KFP12716.1 - 6e-15 55.4 0.1 6.5e-15 55.2 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12716.1 - 1.8e-09 38.1 0.6 3.3e-09 37.2 0.6 1.4 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12716.1 - 8.1e-06 25.8 0.0 8.7e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12716.1 - 0.00018 21.6 0.1 0.00034 20.7 0.1 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12716.1 - 0.0018 18.6 0.4 0.0072 16.6 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP12717.1 - 3.7e-07 30.3 0.1 4e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12717.1 - 0.0042 17.6 0.5 0.0068 17.0 0.5 1.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP12717.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP12718.1 - 4.4e-15 55.8 0.1 4.7e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12718.1 - 2.3e-08 34.5 0.2 3.4e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12718.1 - 1.4e-05 25.1 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12718.1 - 0.0014 18.7 0.3 0.0064 16.6 0.3 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12718.1 - 0.012 16.0 0.2 0.024 15.0 0.2 1.5 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP12719.1 - 1.2e-13 51.2 0.1 1.3e-13 51.1 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12719.1 - 3.2e-07 30.9 0.6 6.6e-07 29.8 0.6 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP12719.1 - 0.00059 19.9 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP12719.1 - 0.0012 19.0 0.1 0.0022 18.2 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.21 KFP12720.1 - 8.4e-21 74.7 0.7 1.4e-20 74.0 0.7 1.4 1 0 0 1 1 1 1 Lectin C-type domain Ldl_recept_a PF00057.18 KFP12720.1 - 3.9e-11 43.0 8.4 3.9e-11 43.0 8.4 3.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A UL45 PF05473.12 KFP12720.1 - 0.0012 18.5 0.4 0.0028 17.3 0.0 1.7 2 0 0 2 2 2 1 UL45 protein, carbohydrate-binding C-type lectin-like Es2 PF09751.9 KFP12721.1 - 2.5e-69 235.1 5.6 2.5e-69 235.1 5.6 2.4 1 1 1 2 2 2 1 Nuclear protein Es2 RED_C PF07807.11 KFP12721.1 - 0.25 11.8 0.2 0.25 11.8 0.2 2.1 3 0 0 3 3 3 0 RED-like protein C-terminal region Homeodomain PF00046.29 KFP12722.1 - 6.9e-23 80.3 4.7 1.2e-22 79.5 4.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP12722.1 - 0.0074 16.2 0.1 0.03 14.2 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain DUF3437 PF11919.8 KFP12722.1 - 0.32 11.0 1.4 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) TSP_1 PF00090.19 KFP12724.1 - 5.5e-10 39.3 5.2 5.5e-10 39.3 5.2 2.4 2 1 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KFP12724.1 - 1.4e-05 25.4 22.6 1.4e-05 25.4 22.6 2.3 2 1 0 2 2 2 1 Somatomedin B domain Lectin_C PF00059.21 KFP12725.1 - 5.4e-13 49.6 0.8 5.4e-13 49.6 0.8 1.4 1 1 1 2 2 2 1 Lectin C-type domain Ribosomal_L13 PF00572.18 KFP12725.1 - 0.047 13.9 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L13 UL45 PF05473.12 KFP12725.1 - 0.12 12.0 0.2 0.14 11.8 0.2 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 KFP12726.1 - 1.3e-17 64.5 1.3 1.3e-17 64.4 0.7 1.4 1 1 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFP12726.1 - 0.16 11.6 0.9 0.36 10.5 0.6 1.9 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1681 PF07933.14 KFP12727.1 - 6.6e-54 181.6 0.0 8.4e-54 181.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Sugar_tr PF00083.24 KFP12728.1 - 3e-160 534.0 26.9 3.4e-160 533.8 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP12728.1 - 7.1e-21 74.5 32.4 3.6e-19 68.9 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KFP12728.1 - 2.4 8.0 5.6 3.6 7.4 0.6 2.9 1 1 1 2 2 2 0 Bacteriophage holin family HP1 Homeodomain PF00046.29 KFP12729.1 - 3.5e-22 78.0 5.3 5.3e-22 77.4 5.3 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP12729.1 - 0.00058 19.3 0.4 0.0011 18.4 0.4 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP12729.1 - 0.0027 17.6 2.0 0.0048 16.8 0.1 2.2 3 0 0 3 3 3 1 Homeobox KN domain Pro-kuma_activ PF09286.11 KFP12729.1 - 0.0047 17.2 0.2 0.0061 16.9 0.2 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Antimicrobial21 PF14861.6 KFP12729.1 - 0.026 14.2 1.8 0.056 13.2 1.8 1.5 1 0 0 1 1 1 0 Plant antimicrobial peptide YdaS_antitoxin PF15943.5 KFP12729.1 - 0.032 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_28 PF13518.6 KFP12729.1 - 0.086 13.0 0.1 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MerR_1 PF13411.6 KFP12729.1 - 0.13 12.4 0.1 0.81 9.8 0.1 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein Homeodomain PF00046.29 KFP12730.1 - 2.9e-21 75.0 5.2 4.9e-21 74.3 5.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP12730.1 - 0.00054 19.8 0.8 0.003 17.4 0.1 2.5 3 0 0 3 3 3 1 Homeobox KN domain Pro-kuma_activ PF09286.11 KFP12730.1 - 0.0017 18.6 0.2 0.0033 17.7 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Homez PF11569.8 KFP12730.1 - 0.0061 16.0 0.5 0.013 15.0 0.5 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFP12730.1 - 0.037 13.9 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 2Fe-2S_thioredx PF01257.19 KFP12730.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin APOBEC4_like PF18774.1 KFP12732.1 - 1.1e-56 190.4 0.5 1.3e-56 190.2 0.5 1.0 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 KFP12732.1 - 5.2e-50 167.8 1.8 8e-50 167.3 1.8 1.3 1 0 0 1 1 1 1 APOBEC1 SNAD4 PF18750.1 KFP12732.1 - 4.4e-37 126.7 1.0 5.2e-37 126.5 1.0 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFP12732.1 - 4.5e-33 114.8 0.8 4.9e-33 114.7 0.8 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KFP12732.1 - 6.6e-27 94.7 0.4 7.3e-27 94.5 0.4 1.0 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 KFP12732.1 - 2.5e-23 83.1 1.1 2.9e-23 82.9 1.1 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC4 PF18775.1 KFP12732.1 - 4.4e-23 81.2 0.1 8.4e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 APOBEC4 APOBEC_N PF08210.11 KFP12732.1 - 3.6e-21 75.9 0.2 4.1e-21 75.7 0.2 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 KFP12732.1 - 2.3e-20 73.1 0.8 2.6e-20 73.0 0.8 1.0 1 0 0 1 1 1 1 APOBEC3 APOBEC_C PF05240.14 KFP12732.1 - 9.8e-14 51.1 1.5 1.2e-13 50.7 0.1 1.8 2 0 0 2 2 2 1 APOBEC-like C-terminal domain dCMP_cyt_deam_1 PF00383.23 KFP12732.1 - 5.3e-05 23.0 0.0 6.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFP12732.1 - 0.034 13.9 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase APOBEC2 PF18772.1 KFP12733.1 - 8.9e-70 234.3 1.5 1e-69 234.1 1.5 1.0 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KFP12733.1 - 2.9e-68 229.4 1.3 3.3e-68 229.2 1.3 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KFP12733.1 - 1.4e-60 204.3 0.7 1.6e-60 204.1 0.7 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 KFP12733.1 - 1.8e-58 197.6 4.7 2.1e-58 197.4 4.7 1.0 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 SNAD4 PF18750.1 KFP12733.1 - 6.3e-37 126.2 0.1 8.7e-37 125.7 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KFP12733.1 - 3e-35 121.3 0.2 3.9e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 APOBEC3 APOBEC_C PF05240.14 KFP12733.1 - 2.6e-29 101.0 0.1 4.5e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain APOBEC4_like PF18774.1 KFP12733.1 - 2.1e-25 89.2 0.2 2.7e-25 88.8 0.2 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC4 PF18775.1 KFP12733.1 - 2.7e-21 75.5 0.0 4.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 APOBEC4 APOBEC1 PF18769.1 KFP12733.1 - 3e-19 69.2 0.0 4.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 APOBEC1 DUF2599 PF10783.9 KFP12733.1 - 0.057 14.1 0.1 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) Toxin-deaminase PF14424.6 KFP12733.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RcbX PF02341.15 KFP12733.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 RbcX protein MAGP PF05507.11 KFP12734.1 - 3.7e-29 101.8 9.6 3.7e-29 101.8 9.6 1.6 2 0 0 2 2 2 1 Microfibril-associated glycoprotein (MAGP) SVWC PF15430.6 KFP12734.1 - 0.033 14.4 3.8 0.11 12.7 0.4 2.4 1 1 1 2 2 2 0 Single domain von Willebrand factor type C RimK PF08443.11 KFP12735.1 - 1.2e-42 145.6 0.0 2.1e-42 144.8 0.0 1.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 KFP12735.1 - 1.1e-11 44.4 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 KFP12735.1 - 6.3e-08 32.2 1.7 0.0054 16.0 0.4 3.1 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KFP12735.1 - 1.1e-07 32.0 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Synapsin_C PF02750.14 KFP12735.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Rimk_N PF18030.1 KFP12735.1 - 0.00023 21.5 0.0 0.00042 20.6 0.0 1.4 1 0 0 1 1 1 1 RimK PreATP-grasp domain ATP-grasp PF02222.22 KFP12735.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KFP12735.1 - 0.0013 18.0 0.0 0.91 8.7 0.0 3.0 1 1 1 2 2 2 2 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KFP12735.1 - 0.0057 16.2 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KFP12735.1 - 0.042 13.3 0.0 0.21 11.0 0.0 2.0 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PHC2_SAM_assoc PF16616.5 KFP12736.1 - 6.6e-28 97.9 5.1 6.6e-28 97.9 5.1 5.9 5 2 1 6 6 6 1 Unstructured region on Polyhomeotic-like protein 1 and 2 SAM_1 PF00536.30 KFP12736.1 - 1.4e-16 60.7 0.0 2.7e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP12736.1 - 6.4e-10 39.0 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP12736.1 - 0.0044 17.0 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain zf-FCS PF06467.14 KFP12736.1 - 0.2 11.6 4.4 0.84 9.6 4.4 2.1 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CGNR PF11706.8 KFP12736.1 - 0.28 11.0 3.6 0.69 9.8 3.6 1.6 1 0 0 1 1 1 0 CGNR zinc finger Man-6-P_recep PF02157.15 KFP12737.1 - 1.3e-127 424.2 0.0 1.5e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KFP12737.1 - 1.2e-13 51.6 0.1 2.4e-13 50.5 0.1 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KFP12737.1 - 5.3e-05 23.3 0.1 0.015 15.4 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 KFP12737.1 - 0.055 13.2 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF5639 PF18690.1 KFP12737.1 - 0.16 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) TED_complement PF07678.14 KFP12738.1 - 2.1e-118 394.9 0.0 3.1e-118 394.3 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP12738.1 - 1.7e-34 119.2 0.8 2.4e-31 108.9 0.0 3.5 3 0 0 3 3 3 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFP12738.1 - 3.9e-31 106.8 0.3 1.4e-30 105.0 0.3 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFP12738.1 - 3.9e-27 94.8 1.9 2.3e-26 92.3 1.1 2.8 2 0 0 2 2 2 1 A-macroglobulin receptor binding domain MG3 PF17791.1 KFP12738.1 - 2e-24 85.6 3.2 3.6e-24 84.8 0.7 2.8 3 0 0 3 3 3 1 Macroglobulin domain MG3 MG4 PF17789.1 KFP12738.1 - 2.2e-22 79.0 0.0 1.3e-21 76.6 0.0 2.5 1 0 0 1 1 1 1 Macroglobulin domain MG4 MG2 PF01835.19 KFP12738.1 - 1.3e-14 54.4 0.0 7.1e-14 52.0 0.0 2.4 1 0 0 1 1 1 1 MG2 domain SVA PF05326.11 KFP12738.1 - 0.00036 20.5 0.1 0.002 18.1 0.1 2.3 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.6 KFP12738.1 - 0.00061 20.0 1.0 0.008 16.4 0.1 3.3 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KFP12738.1 - 0.0022 17.9 0.3 0.018 15.0 0.0 2.7 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) MG1 PF17790.1 KFP12738.1 - 0.071 13.5 0.3 2.1 8.8 0.0 3.1 2 0 0 2 2 2 0 Macroglobulin domain MG1 TED_complement PF07678.14 KFP12739.1 - 8e-116 386.4 0.4 1.2e-115 385.9 0.4 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP12739.1 - 5.8e-32 110.9 3.4 2.3e-29 102.5 0.1 3.5 3 0 0 3 3 3 2 Alpha-2-macroglobulin bait region domain A2M PF00207.22 KFP12739.1 - 4e-28 97.1 0.0 1.6e-27 95.2 0.0 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFP12739.1 - 3.8e-26 91.6 1.7 1.1e-25 90.2 1.7 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 KFP12739.1 - 7.3e-25 87.1 2.9 1.5e-24 86.1 0.7 2.7 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 KFP12739.1 - 2.3e-21 75.7 1.0 5.3e-20 71.4 0.0 3.7 4 0 0 4 4 4 1 Macroglobulin domain MG4 MG2 PF01835.19 KFP12739.1 - 5.9e-19 68.3 0.1 4.1e-18 65.6 0.0 2.6 3 0 0 3 3 2 1 MG2 domain SVA PF05326.11 KFP12739.1 - 0.0018 18.2 1.9 0.0039 17.2 0.0 2.5 3 0 0 3 3 3 1 Seminal vesicle autoantigen (SVA) MG1 PF17790.1 KFP12739.1 - 0.0044 17.4 0.0 0.024 15.1 0.0 2.4 1 0 0 1 1 1 1 Macroglobulin domain MG1 Big_1 PF02369.16 KFP12739.1 - 0.011 15.7 1.9 0.032 14.2 0.6 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Prenyltrans PF00432.21 KFP12739.1 - 0.25 11.1 1.9 0.63 9.8 0.3 2.6 2 1 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat DUF1433 PF07252.11 KFP12739.1 - 0.27 11.5 2.9 0.39 11.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) UPF0767 PF15990.5 KFP12741.1 - 3.2e-28 97.7 0.0 3.6e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 UPF0767 family Connexin PF00029.19 KFP12742.1 - 3.3e-98 328.1 2.0 4e-98 327.8 2.0 1.1 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.13 KFP12742.1 - 0.24 11.0 4.0 0.51 9.9 4.0 1.5 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) TssO PF17561.2 KFP12742.1 - 0.62 10.2 0.1 0.62 10.2 0.1 2.1 3 0 0 3 3 3 0 Type VI secretion system, TssO Connexin PF00029.19 KFP12743.1 - 3e-46 158.1 8.2 7e-26 91.4 0.2 2.1 1 1 1 2 2 2 2 Connexin 7tm_1 PF00001.21 KFP12743.1 - 0.039 13.3 4.3 0.13 11.6 4.3 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) stn_TNFRSF12A PF12191.8 KFP12743.1 - 0.04 14.1 0.1 0.058 13.6 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SCIMP PF15050.6 KFP12743.1 - 0.069 13.6 0.4 0.11 12.9 0.4 1.3 1 0 0 1 1 1 0 SCIMP protein COX14 PF14880.6 KFP12743.1 - 0.15 11.9 0.3 0.15 11.9 0.3 1.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4688 PF15752.5 KFP12744.1 - 3.1e-40 138.6 21.0 3.3e-40 138.5 21.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4688) DUF4688 PF15752.5 KFP12745.1 - 3.5e-11 43.0 1.1 2.4e-10 40.2 1.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4688) CUB PF00431.20 KFP12746.1 - 1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 KFP12746.1 - 5.9e-09 36.4 0.2 9.7e-09 35.7 0.2 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) ArfGap PF01412.18 KFP12747.1 - 1.8e-32 111.9 0.1 3.5e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 KFP12748.1 - 1.3e-16 60.8 0.0 2.2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain CBFD_NFYB_HMF PF00808.23 KFP12749.1 - 1.1e-21 76.9 2.4 3.8e-21 75.1 1.6 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP12749.1 - 1.5e-15 57.7 1.1 1.5e-15 57.7 1.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFP12749.1 - 0.043 14.1 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X KCNQ_channel PF03520.14 KFP12750.1 - 1.5e-89 298.9 0.1 2e-89 298.5 0.1 1.1 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel 7tm_4 PF13853.6 KFP12751.1 - 4.7e-47 161.0 10.7 5.7e-47 160.8 10.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12751.1 - 1.8e-29 102.9 12.2 2.7e-29 102.3 12.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP12751.1 - 0.015 14.9 10.6 0.044 13.4 10.6 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Rax2 PF12768.7 KFP12751.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity 7tm_4 PF13853.6 KFP12752.1 - 2.8e-42 145.4 12.6 3.4e-42 145.1 12.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12752.1 - 1.8e-30 106.1 13.7 2.5e-30 105.7 13.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12752.1 - 0.00015 21.2 9.6 0.00016 21.2 8.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEMspv1-c74-12 PF11044.8 KFP12752.1 - 0.0075 16.2 1.8 0.0075 16.2 1.8 2.4 2 0 0 2 2 2 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein 7tm_4 PF13853.6 KFP12753.1 - 7.9e-43 147.2 13.9 9.2e-43 147.0 13.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12753.1 - 4.6e-27 95.0 17.5 7.7e-27 94.3 17.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.6 KFP12753.1 - 0.17 12.1 0.5 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 7tm_4 PF13853.6 KFP12754.1 - 9.6e-35 120.7 4.9 1.1e-34 120.5 4.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12754.1 - 4.2e-17 62.3 11.3 6.3e-17 61.8 11.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP12755.1 - 3.4e-49 168.1 13.2 4e-49 167.8 13.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP12755.1 - 2.2e-27 96.1 14.0 3.5e-27 95.4 14.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12755.1 - 0.00024 20.6 10.9 0.00035 20.0 10.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx adh_short PF00106.25 KFP12756.1 - 2.6e-54 183.6 0.0 3.4e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP12756.1 - 7.1e-31 107.6 0.0 9.5e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP12756.1 - 1.7e-13 50.9 0.0 2.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFP12756.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFP12756.1 - 0.0017 18.6 0.1 0.0031 17.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 KFP12756.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) ApbA PF02558.16 KFP12756.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Vps4_C PF09336.10 KFP12757.1 - 8.6e-30 102.5 0.2 1.4e-29 101.9 0.2 1.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFP12757.1 - 5.8e-09 35.6 0.0 2.3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KFP12757.1 - 0.0002 21.8 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFP12758.1 - 2.4e-31 108.9 0.0 2.9e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFP12758.1 - 2.2e-06 27.1 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFP12758.1 - 2.2e-06 27.5 0.0 3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFP12758.1 - 2.5e-06 27.8 0.1 0.0021 18.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KFP12758.1 - 2.5e-06 28.0 0.0 0.00073 20.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFP12758.1 - 1e-05 25.4 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFP12758.1 - 1.4e-05 25.1 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFP12758.1 - 1.7e-05 24.9 0.0 4e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFP12758.1 - 6.6e-05 23.5 0.0 0.00011 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFP12758.1 - 9.7e-05 22.0 0.1 0.32 10.5 0.1 2.1 1 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 KFP12758.1 - 0.00011 21.5 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 KFP12758.1 - 0.00024 21.3 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFP12758.1 - 0.00093 19.4 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KFP12758.1 - 0.0016 17.8 0.1 0.78 9.0 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_24 PF13479.6 KFP12758.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFP12758.1 - 0.0024 18.2 0.0 0.0036 17.7 0.0 1.3 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 KFP12758.1 - 0.0027 17.6 0.0 0.068 13.1 0.0 2.1 1 1 1 2 2 2 1 NACHT domain TniB PF05621.11 KFP12758.1 - 0.0031 17.0 0.0 1.4 8.3 0.0 2.1 1 1 1 2 2 2 2 Bacterial TniB protein AAA_7 PF12775.7 KFP12758.1 - 0.0037 16.8 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFP12758.1 - 0.0065 15.9 0.1 0.015 14.7 0.0 1.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFP12758.1 - 0.0071 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Sigma54_activat PF00158.26 KFP12758.1 - 0.0094 15.7 0.0 0.042 13.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 KFP12758.1 - 0.018 14.4 0.0 0.57 9.4 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KFP12758.1 - 0.022 14.7 0.0 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 KFP12758.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_30 PF13604.6 KFP12758.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFP12758.1 - 0.038 14.4 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KFP12758.1 - 0.049 13.7 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Torsin ResIII PF04851.15 KFP12758.1 - 0.049 13.6 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KFP12758.1 - 0.053 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 KFP12758.1 - 0.054 12.7 0.1 0.37 10.0 0.1 1.9 1 1 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KFP12758.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KFP12758.1 - 0.061 13.4 0.0 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Parvo_NS1 PF01057.17 KFP12758.1 - 0.067 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFP12758.1 - 0.075 13.3 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP12758.1 - 0.095 13.2 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.21 KFP12758.1 - 0.099 12.3 0.0 0.28 10.8 0.0 1.7 1 1 0 2 2 2 0 Guanylate kinase AFG1_ATPase PF03969.16 KFP12758.1 - 0.1 11.5 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_29 PF13555.6 KFP12758.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFP12758.1 - 0.12 12.2 0.5 11 5.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Serpin PF00079.20 KFP12759.1 - 7.9e-101 338.0 7.2 8.9e-101 337.9 7.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Toprim_Crpt PF13342.6 KFP12759.1 - 0.016 15.2 0.9 0.44 10.5 0.3 3.1 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase E2_bind PF08825.10 KFP12759.1 - 0.25 11.5 2.6 16 5.8 0.5 2.5 2 0 0 2 2 2 0 E2 binding domain Serpin PF00079.20 KFP12760.1 - 4.4e-80 269.8 0.6 4.9e-80 269.6 0.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF5605 PF18310.1 KFP12760.1 - 0.13 12.2 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) Serpin PF00079.20 KFP12761.1 - 3.9e-79 266.6 0.2 4.4e-79 266.5 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFP12761.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 Serpin PF00079.20 KFP12762.1 - 3.6e-78 263.5 0.2 4e-78 263.3 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFP12762.1 - 0.02 15.1 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 DNA_pol3_beta PF00712.19 KFP12762.1 - 0.1 12.8 0.2 0.29 11.3 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain Serpin PF00079.20 KFP12763.1 - 2.8e-76 257.3 0.1 3.1e-76 257.1 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Sec-ASP3 PF15432.6 KFP12763.1 - 0.095 12.8 0.2 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 EF1_GNE PF00736.19 KFP12763.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain Serpin PF00079.20 KFP12764.1 - 7.4e-128 427.0 2.2 8.3e-128 426.8 2.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFP12765.1 - 1.5e-134 449.0 7.0 1.7e-134 448.9 7.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFP12766.1 - 6.2e-135 450.3 1.7 7e-135 450.1 1.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4393 PF14337.6 KFP12766.1 - 0.031 14.1 1.2 0.062 13.1 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) bacHORMA_2 PF18173.1 KFP12766.1 - 0.042 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial HORMA domain 2 TetR_C_26 PF17934.1 KFP12766.1 - 0.046 14.1 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Serpin PF00079.20 KFP12767.1 - 5e-130 434.1 0.2 5.8e-130 433.9 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MgsA_C PF12002.8 KFP12768.1 - 6.5e-59 198.6 0.0 2.1e-58 196.9 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KFP12768.1 - 1.9e-25 89.0 0.0 4.7e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFP12768.1 - 2.9e-09 37.4 0.4 5.2e-09 36.6 0.4 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP12768.1 - 5.5e-05 23.0 0.2 0.00014 21.6 0.2 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KFP12768.1 - 0.0046 16.7 0.0 0.017 14.9 0.0 1.8 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KFP12768.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KFP12768.1 - 0.07 12.9 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.15 KFP12768.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GDP_Man_Dehyd PF16363.5 KFP12769.1 - 5.6e-158 525.6 0.0 6.2e-158 525.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFP12769.1 - 6.4e-69 232.1 0.0 8.8e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFP12769.1 - 0.0004 19.6 0.0 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Sec5 PF15469.6 KFP12770.1 - 4.5e-55 186.4 0.8 1.7e-54 184.5 0.1 2.5 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.24 KFP12770.1 - 1.7e-08 34.4 0.6 3.4e-08 33.5 0.6 1.5 1 0 0 1 1 1 1 IPT/TIG domain SAM_2 PF07647.17 KFP12770.1 - 0.013 15.6 0.1 0.066 13.3 0.1 2.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) IRF-3 PF10401.9 KFP12771.1 - 3.4e-65 219.2 0.1 4.5e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFP12771.1 - 1.9e-42 143.8 0.2 2.9e-42 143.2 0.2 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KFP12771.1 - 0.005 17.1 0.0 0.0076 16.5 0.0 1.2 1 0 0 1 1 1 1 MH2 domain DSPc PF00782.20 KFP12772.1 - 4.5e-26 91.2 0.4 7.9e-25 87.2 0.1 2.2 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP12772.1 - 0.00064 19.4 0.6 0.0008 19.0 0.1 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Complex1_LYR PF05347.15 KFP12772.1 - 0.0041 17.1 1.1 0.012 15.6 1.1 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Flavodoxin_2 PF02525.17 KFP12773.1 - 5.5e-51 173.1 0.0 6.6e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KFP12773.1 - 1.7e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 KFP12773.1 - 0.0046 16.7 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Pkinase_Tyr PF07714.17 KFP12774.1 - 9.7e-51 172.5 0.1 1.4e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12774.1 - 3.8e-50 170.7 0.3 7e-50 169.8 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Death PF00531.22 KFP12774.1 - 1.8e-20 72.9 0.7 1.4e-19 70.0 0.3 2.6 2 0 0 2 2 2 1 Death domain RHIM PF12721.7 KFP12774.1 - 3e-09 37.2 4.1 1e-08 35.5 4.1 2.0 1 0 0 1 1 1 1 RIP homotypic interaction motif RIO1 PF01163.22 KFP12774.1 - 0.003 17.2 0.1 0.0056 16.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP12774.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP12774.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RecG_wedge PF17191.4 KFP12774.1 - 0.11 12.1 0.1 4.7 6.8 0.0 2.9 3 0 0 3 3 3 0 RecG wedge domain APH PF01636.23 KFP12774.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 KFP12775.1 - 4.2e-21 75.7 0.0 3.5e-16 59.6 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP12775.1 - 6.4e-13 48.5 0.0 2.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP12775.1 - 2.5e-08 34.8 0.0 3.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFP12775.1 - 0.0009 18.9 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFP12775.1 - 0.0032 17.1 0.1 0.02 14.6 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KFP12775.1 - 0.004 17.1 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KFP12775.1 - 0.013 15.0 0.0 0.18 11.3 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KFP12775.1 - 0.047 13.3 0.2 0.14 11.8 0.2 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 KFP12775.1 - 0.094 12.5 0.0 9.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PARP PF00644.20 KFP12776.1 - 3.9e-32 111.4 0.0 4.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 KFP12776.1 - 0.0011 19.2 0.1 0.0023 18.1 0.1 1.6 1 0 0 1 1 1 1 ARTD15 N-terminal domain SdpI PF13630.6 KFP12776.1 - 0.028 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family Ig_3 PF13927.6 KFP12777.1 - 2.9e-12 47.0 0.0 1.1e-11 45.2 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12777.1 - 3.3e-11 43.4 0.0 7.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain CarbopepD_reg_2 PF13715.6 KFP12777.1 - 1.7e-10 40.7 0.1 1.9e-05 24.6 0.0 2.9 2 0 0 2 2 2 2 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 KFP12777.1 - 2.9e-09 37.1 0.6 7.4e-08 32.6 0.0 2.9 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain I-set PF07679.16 KFP12777.1 - 1.3e-07 31.6 0.0 3.5e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain TSP_1 PF00090.19 KFP12777.1 - 2.7e-06 27.5 10.6 2.7e-06 27.5 10.6 3.2 3 0 0 3 3 3 1 Thrombospondin type 1 domain ig PF00047.25 KFP12777.1 - 3.8e-06 27.0 0.0 1.6e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain DUF1533 PF07550.11 KFP12777.1 - 0.076 12.9 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) bMG3 PF11974.8 KFP12777.1 - 0.085 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Formyl_trans_N PF00551.19 KFP12778.1 - 4e-24 85.3 0.0 6.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFP12778.1 - 1.4e-10 41.3 0.1 4.4e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain OSTbeta PF15048.6 KFP12779.1 - 9e-34 116.2 0.1 1.1e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein Saf_2TM PF18303.1 KFP12779.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain DUF5472 PF17566.2 KFP12779.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5472) MHYT PF03707.16 KFP12779.1 - 0.056 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF3098 PF11297.8 KFP12779.1 - 0.088 12.4 0.3 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) CENP-O PF09496.10 KFP12779.1 - 0.099 12.6 0.3 0.14 12.1 0.4 1.3 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Ras PF00071.22 KFP12780.1 - 5.1e-14 52.2 0.0 6.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Ras family UBA PF00627.31 KFP12781.1 - 9e-05 22.3 0.8 0.018 15.0 0.1 2.3 2 0 0 2 2 2 2 UBA/TS-N domain Sigma54_CBD PF04963.13 KFP12781.1 - 0.011 15.7 0.4 0.011 15.6 0.4 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain WIYLD PF10440.9 KFP12781.1 - 0.018 14.8 0.0 2.2 8.1 0.0 2.7 1 1 2 3 3 3 0 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 KFP12781.1 - 0.035 13.9 1.1 0.9 9.4 0.7 2.5 2 1 0 2 2 2 0 Fungal ubiquitin-associated domain Raf1_HTH PF18579.1 KFP12781.1 - 0.097 12.4 0.3 2.9 7.7 0.0 2.1 1 1 1 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain PDCD7 PF16021.5 KFP12783.1 - 6.6e-85 284.9 7.2 7.3e-85 284.8 7.2 1.0 1 0 0 1 1 1 1 Programmed cell death protein 7 CENP-Q PF13094.6 KFP12783.1 - 0.058 13.6 13.8 0.27 11.4 8.7 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_2 PF07724.14 KFP12784.1 - 1.9e-41 142.0 0.0 3.2e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KFP12784.1 - 4e-15 55.6 0.0 9.6e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFP12784.1 - 1.1e-13 51.7 0.0 2.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP12784.1 - 1.2e-05 25.3 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFP12784.1 - 2.4e-05 24.1 0.0 0.0002 21.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 KFP12784.1 - 6.9e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFP12784.1 - 9.2e-05 21.9 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFP12784.1 - 0.00028 21.2 0.1 0.001 19.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP12784.1 - 0.0026 18.2 0.0 0.0075 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFP12784.1 - 0.0058 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP12784.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KFP12784.1 - 0.0069 16.5 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KFP12784.1 - 0.0079 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 KFP12784.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 KFP12784.1 - 0.022 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFP12784.1 - 0.026 14.5 0.3 0.074 13.0 0.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KFP12784.1 - 0.057 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP12784.1 - 0.061 13.8 0.1 0.17 12.4 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 KFP12784.1 - 0.065 13.8 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFP12784.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain PduV-EutP PF10662.9 KFP12784.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KFP12784.1 - 0.17 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KFP12784.1 - 0.17 11.0 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 KFP12784.1 - 0.18 11.3 0.0 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain zinc_ribbon_4 PF13717.6 KFP12784.1 - 0.21 11.6 4.9 9.1 6.3 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFP12784.1 - 0.47 10.5 4.4 0.91 9.6 4.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.17 KFP12784.1 - 0.7 9.6 4.3 2.4 8.0 3.9 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 Abhydrolase_1 PF00561.20 KFP12785.1 - 2.5e-08 33.9 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP12785.1 - 1.3e-06 29.2 0.0 1.6e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP12785.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFP12785.1 - 0.0038 16.0 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 KFP12785.1 - 0.0072 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KFP12785.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFP12785.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_trans_4_4 PF13579.6 KFP12785.1 - 0.22 12.0 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Ank_4 PF13637.6 KFP12786.1 - 1.9e-46 155.9 17.7 5.3e-11 42.8 0.2 6.1 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP12786.1 - 1e-45 154.2 12.1 2.2e-17 63.4 2.0 3.7 1 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP12786.1 - 1e-44 150.0 13.5 4.6e-11 42.7 0.0 8.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP12786.1 - 4.2e-34 112.7 11.9 4.9e-05 23.4 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KFP12786.1 - 5.4e-32 108.8 14.1 1.2e-08 34.9 0.1 9.0 9 0 0 9 9 9 8 Ankyrin repeat Death PF00531.22 KFP12786.1 - 0.0094 16.1 0.4 0.028 14.6 0.4 1.8 1 0 0 1 1 1 1 Death domain VWA_3_C PF18571.1 KFP12786.1 - 0.094 12.6 0.5 1.1 9.2 0.1 3.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Peptidase_S8 PF00082.22 KFP12787.1 - 1e-49 169.4 0.3 1.5e-49 168.9 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP12787.1 - 3.6e-32 110.2 0.1 5.9e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.6 KFP12787.1 - 5.4e-14 52.1 53.2 2.3e-10 40.4 31.9 4.0 1 1 3 4 4 4 3 Growth factor receptor domain IV S8_pro-domain PF16470.5 KFP12787.1 - 1.3e-13 51.5 1.3 2.7e-13 50.5 1.3 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 KFP12787.1 - 7.1e-12 45.4 61.2 3.9e-06 27.0 18.2 4.1 2 2 1 3 3 3 3 Furin-like repeat, cysteine-rich PLAC PF08686.11 KFP12787.1 - 1.5e-06 28.8 10.1 1.5e-06 28.8 10.1 3.2 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain VSP PF03302.13 KFP12787.1 - 0.45 9.3 59.4 0.15 10.9 11.6 4.4 1 1 3 4 4 4 0 Giardia variant-specific surface protein LRR_9 PF14580.6 KFP12788.1 - 2.3e-78 261.7 1.4 2.8e-78 261.4 1.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP12788.1 - 9.9e-08 32.2 8.1 0.00048 20.5 2.3 2.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP12788.1 - 2.5e-05 23.9 5.4 0.00013 21.6 4.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat Selenoprotein_S PF06936.11 KFP12789.1 - 3.5e-60 203.1 8.0 3.9e-60 203.0 8.0 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Trp_oprn_chp PF09534.10 KFP12789.1 - 0.35 10.7 2.1 0.56 10.0 2.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CHGN PF05679.16 KFP12790.1 - 7e-202 671.8 1.6 8.1e-202 671.6 1.6 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFP12790.1 - 6.5e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 KFP12790.1 - 1.5e-09 37.3 0.2 3.8e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP12790.1 - 4.6e-06 26.3 0.6 0.00016 21.2 0.1 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 KFP12790.1 - 0.00024 21.0 0.1 0.0049 16.7 0.1 2.9 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.6 KFP12790.1 - 0.014 14.9 0.0 0.23 10.9 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 21 Pkinase PF00069.25 KFP12792.1 - 3.6e-38 131.5 0.0 1.4e-37 129.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12792.1 - 2.8e-36 125.2 0.0 4.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KFP12792.1 - 2.6e-26 91.1 21.4 3e-07 30.1 2.2 6.3 6 0 0 6 6 6 5 Leucine rich repeat COR PF16095.5 KFP12792.1 - 1.1e-24 87.4 0.1 2.3e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 KFP12792.1 - 1.4e-22 80.2 0.0 5.2e-22 78.3 0.0 2.1 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 KFP12792.1 - 2.4e-22 78.6 30.6 1.1e-05 25.7 1.1 8.1 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KFP12792.1 - 4.7e-13 49.5 0.5 3.5e-05 24.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP12792.1 - 7.4e-07 29.6 0.2 0.0059 17.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP12792.1 - 1.7e-06 27.9 0.9 0.34 11.6 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat Ras PF00071.22 KFP12792.1 - 2.8e-06 27.0 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP12792.1 - 7.3e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_5 PF13857.6 KFP12792.1 - 0.00047 20.4 2.7 3.5 8.1 0.0 4.5 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP12792.1 - 0.00061 20.1 0.5 1.9 9.1 0.1 3.9 3 1 0 3 3 3 1 Ankyrin repeat LRR_1 PF00560.33 KFP12792.1 - 0.00099 19.3 21.9 12 6.9 0.0 9.7 8 1 1 9 9 9 0 Leucine Rich Repeat MMR_HSR1 PF01926.23 KFP12792.1 - 0.036 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP12792.1 - 0.038 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region malic PF00390.19 KFP12792.1 - 0.07 12.9 0.2 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain TniB PF05621.11 KFP12792.1 - 0.071 12.5 0.2 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial TniB protein LRR_6 PF13516.6 KFP12792.1 - 5.7 7.3 25.4 2.6 8.3 0.3 8.1 8 0 0 8 8 8 0 Leucine Rich repeat Aldedh PF00171.22 KFP12793.1 - 3.3e-184 612.7 0.0 3.7e-184 612.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFP12793.1 - 0.007 15.8 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LINES_N PF14694.6 KFP12794.1 - 6.7e-139 463.2 9.1 1.3e-138 462.2 9.1 1.5 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 KFP12794.1 - 1.2e-17 63.0 1.2 3e-17 61.7 1.2 1.7 1 0 0 1 1 1 1 Lines C-terminus GON PF08685.11 KFP12795.1 - 0.19 11.6 0.0 0.19 11.6 0.0 1.0 1 0 0 1 1 1 0 GON domain TSP_1 PF00090.19 KFP12797.1 - 4.9e-25 87.5 86.3 1.5e-10 41.1 10.3 7.2 6 1 0 6 6 5 4 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KFP12797.1 - 1.2e-22 80.1 12.5 9.2e-21 74.1 6.6 7.4 6 2 1 7 7 5 2 ADAM cysteine-rich domain ADAM_spacer1 PF05986.14 KFP12797.1 - 5.7e-21 74.7 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 KFP12797.1 - 7.1e-21 75.0 0.7 8.9e-16 58.4 0.2 2.7 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFP12797.1 - 2.8e-13 50.5 0.5 8.9e-13 48.8 0.5 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP12797.1 - 2e-10 41.2 0.0 4.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP12797.1 - 3e-07 30.6 0.7 9.8e-07 28.8 0.7 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP12797.1 - 3.7e-05 23.5 1.9 7.6e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFP12797.1 - 0.0026 18.5 9.4 0.0026 18.5 9.4 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFP12797.1 - 0.0051 16.7 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KFP12797.1 - 0.13 11.2 0.2 0.27 10.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 SRF-TF PF00319.18 KFP12800.1 - 5.7e-24 83.3 0.4 9.6e-24 82.6 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFP12800.1 - 3.6e-07 30.1 0.0 3.6e-07 30.1 0.0 3.0 4 0 0 4 4 4 1 Holliday junction regulator protein family C-terminal repeat GHD PF17834.1 KFP12800.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Filament PF00038.21 KFP12803.1 - 3.8e-07 30.0 2.5 3.8e-07 30.0 2.5 2.5 3 0 0 3 3 3 1 Intermediate filament protein BET PF17035.5 KFP12803.1 - 0.095 12.9 2.1 0.38 11.0 0.9 2.7 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Pkinase_Tyr PF07714.17 KFP12804.1 - 3.2e-95 318.3 0.0 4.7e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12804.1 - 2.4e-40 138.6 0.0 3.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFP12804.1 - 8.5e-33 113.3 34.2 8.5e-33 113.3 34.2 2.1 2 0 0 2 2 2 1 Furin-like cysteine rich region Recep_L_domain PF01030.24 KFP12804.1 - 5.9e-30 103.7 0.7 1.1e-29 102.8 0.7 1.5 1 0 0 1 1 1 1 Receptor L domain fn3 PF00041.21 KFP12804.1 - 2.4e-19 69.4 6.3 2.3e-06 27.9 0.1 4.7 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.6 KFP12804.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Insulin_TMD PF17870.1 KFP12804.1 - 0.19 11.8 0.4 0.46 10.6 0.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Peptidase_C15 PF01470.17 KFP12806.1 - 7.4e-18 65.5 0.0 9.3e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 KFP12806.1 - 2.6e-05 24.0 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 Acetyltransf_7 PF13508.7 KFP12807.1 - 0.0059 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFP12807.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFP12807.1 - 0.028 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 KFP12807.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Arrestin_C PF02752.22 KFP12809.1 - 1e-22 81.0 0.1 3.1e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFP12809.1 - 1.2e-19 70.8 0.0 3e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KFP12809.1 - 0.04 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Rgp1 Vps26 PF03643.15 KFP12809.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Hormone_recep PF00104.30 KFP12811.1 - 1.6e-39 135.6 0.1 2.4e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP12811.1 - 8.4e-31 106.2 17.1 8.4e-31 106.2 17.1 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) C2 PF00168.30 KFP12814.1 - 6.1e-32 110.0 0.1 1.9e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 C2 domain cPLA2_C2 PF18695.1 KFP12814.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain DUF4497 PF14924.6 KFP12814.1 - 0.025 15.1 0.0 2 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) 2OG-FeII_Oxy_4 PF13661.6 KFP12814.1 - 0.06 14.0 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4628 PF15429.6 KFP12815.1 - 0.0057 16.4 0.2 0.0072 16.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) RGM_C PF06534.13 KFP12817.1 - 2.4e-73 245.3 0.0 3.5e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.12 KFP12817.1 - 2.8e-72 242.3 1.6 4.2e-72 241.7 1.6 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus C8 PF08742.11 KFP12817.1 - 1.3 9.5 6.0 2.5 8.6 0.0 3.0 3 0 0 3 3 3 0 C8 domain SNF2_N PF00176.23 KFP12818.1 - 4.8e-67 226.1 0.3 9.6e-67 225.2 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDH1_2_SANT_HL1 PF18375.1 KFP12818.1 - 4.2e-34 117.1 0.0 4.2e-34 117.1 0.0 5.7 5 1 0 5 5 5 1 CDH1/2 SANT-Helical linker 1 Chromo PF00385.24 KFP12818.1 - 4.9e-32 109.6 11.5 3.2e-21 75.0 0.0 3.8 3 1 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFP12818.1 - 4.2e-25 88.0 0.9 4.2e-25 88.0 0.9 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFP12818.1 - 6.8e-20 71.5 0.0 2.7e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP12818.1 - 2.7e-08 34.0 0.0 2.7e-08 34.0 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 KFP12818.1 - 0.00041 20.6 0.1 0.022 14.9 0.0 3.3 2 1 0 2 2 2 1 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.31 KFP12818.1 - 0.0028 17.8 0.1 0.053 13.7 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1180 PF06679.12 KFP12819.1 - 5.7e-19 69.1 1.1 6e-19 69.1 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) OATP PF03137.20 KFP12822.1 - 1.3e-175 584.8 7.6 1.6e-175 584.6 7.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFP12822.1 - 3.3e-26 92.0 9.1 3.3e-26 92.0 9.1 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KFP12822.1 - 7.9e-07 29.1 14.0 1.3e-06 28.4 10.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP12822.1 - 0.01 15.8 8.8 0.049 13.7 8.8 2.1 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain PUCC PF03209.15 KFP12822.1 - 0.19 10.7 13.4 0.27 10.2 0.1 3.8 4 0 0 4 4 4 0 PUCC protein D_CNTX PF17492.2 KFP12822.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.4 4 0 0 4 4 4 0 Delta Ctenitoxins MFS_1 PF07690.16 KFP12823.1 - 4.2e-38 131.2 27.8 4e-25 88.5 16.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP12823.1 - 1.8e-34 119.4 19.2 3.3e-30 105.3 7.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFP12823.1 - 2.8e-08 33.8 4.8 4.8e-08 33.1 4.8 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFP12823.1 - 0.00071 19.0 9.7 0.00071 19.0 9.7 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KFP12823.1 - 0.00094 18.1 6.5 0.043 12.7 1.0 2.5 2 1 0 2 2 2 2 MFS_1 like family Pentapeptide_3 PF13576.6 KFP12823.1 - 0.0018 18.4 3.2 0.055 13.6 2.2 2.9 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) MFS_3 PF05977.13 KFP12823.1 - 0.025 13.0 6.8 0.27 9.6 1.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Ank_2 PF12796.7 KFP12824.1 - 0.008 16.7 0.0 0.027 15.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH_16 PF17838.1 KFP12825.1 - 4.2e-40 136.5 1.5 6.3e-40 135.9 0.4 2.0 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.20 KFP12825.1 - 5e-31 108.3 6.9 5e-31 108.3 6.9 3.0 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFP12825.1 - 2.9e-05 24.5 1.3 0.0001 22.8 0.0 2.7 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 KFP12825.1 - 5.2e-05 23.0 7.7 0.00011 22.0 7.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFP12825.1 - 0.018 15.4 4.1 0.042 14.2 4.1 1.6 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 KFP12825.1 - 0.17 11.8 6.2 0.41 10.6 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFP12825.1 - 0.22 11.2 6.0 0.45 10.2 6.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CBF PF03914.17 KFP12825.1 - 2.2 8.3 6.9 0.39 10.7 0.1 3.1 3 0 0 3 3 3 0 CBF/Mak21 family DZR PF12773.7 KFP12825.1 - 3.7 7.6 6.4 13 5.9 6.4 1.9 1 0 0 1 1 1 0 Double zinc ribbon Kelch_1 PF01344.25 KFP12826.1 - 2.8e-51 170.9 9.7 2e-11 43.3 0.1 6.0 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP12826.1 - 1.6e-33 114.8 3.5 1.8e-33 114.7 2.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP12826.1 - 1.3e-30 104.7 4.3 4.3e-06 26.8 0.0 6.2 3 2 3 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFP12826.1 - 1.5e-28 98.5 2.0 9.4e-06 25.8 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFP12826.1 - 6e-26 90.9 0.3 1.2e-25 89.8 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP12826.1 - 2.1e-25 87.7 5.7 0.00019 21.3 0.1 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP12826.1 - 1.5e-23 82.5 1.1 6.8e-08 32.4 0.0 5.7 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP12826.1 - 1.3e-13 50.6 3.0 1.3e-06 28.3 0.0 5.5 5 0 0 5 5 5 2 Kelch motif DUF1668 PF07893.13 KFP12826.1 - 0.0072 15.7 0.2 0.035 13.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) DUF3342 PF11822.8 KFP12826.1 - 0.0083 16.3 0.0 0.035 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Root_cap PF06830.11 KFP12826.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Root cap Pepdidase_M14_N PF18027.1 KFP12827.1 - 1.1e-11 45.0 0.4 2.4e-11 43.9 0.4 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KFP12827.1 - 4.2e-11 43.2 0.0 7.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KFP12827.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Neurochondrin PF05536.11 KFP12827.1 - 0.17 10.3 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin Cohesin_load PF10345.9 KFP12828.1 - 3.7e-108 362.6 11.4 4.4e-108 362.3 11.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_2 PF07719.17 KFP12828.1 - 1.7e-07 30.8 5.4 0.22 11.7 0.2 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP12828.1 - 3e-07 30.6 13.6 0.0016 18.7 0.0 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP12828.1 - 4.9e-05 22.9 14.5 0.0061 16.0 0.1 3.8 2 1 1 4 4 4 2 MalT-like TPR region TPR_8 PF13181.6 KFP12828.1 - 9.6e-05 22.3 5.8 1.3 9.4 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP12828.1 - 0.00088 19.1 0.1 3.6 7.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP12828.1 - 0.0028 17.4 5.1 1.7 8.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat HemY_N PF07219.13 KFP12828.1 - 0.0058 16.8 1.2 0.083 13.1 0.0 3.0 3 0 0 3 3 3 1 HemY protein N-terminus TPR_19 PF14559.6 KFP12828.1 - 0.066 13.7 4.7 1.8 9.1 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP12828.1 - 0.09 12.5 0.1 6.5 6.5 0.0 3.3 3 0 0 3 3 3 0 TPR repeat DUF4110 PF13422.6 KFP12828.1 - 0.12 12.5 0.0 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) ANAPC3 PF12895.7 KFP12828.1 - 0.77 10.0 8.6 6 7.2 0.6 4.1 3 2 2 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Surp PF01805.20 KFP12829.1 - 1.6e-28 98.5 3.3 2.6e-15 56.1 0.1 2.9 2 0 0 2 2 2 2 Surp module G-patch PF01585.23 KFP12829.1 - 2.6e-14 52.8 3.3 7.6e-14 51.3 3.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP12829.1 - 5.7e-07 29.5 1.1 9.9e-06 25.6 0.2 2.9 2 0 0 2 2 2 1 G-patch domain RtcB PF01139.17 KFP12829.1 - 0.016 14.4 0.3 0.029 13.5 0.3 1.4 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Tuberculin PF12198.8 KFP12829.1 - 0.045 13.9 0.0 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein Pannexin_like PF12534.8 KFP12830.1 - 1.2e-149 498.2 4.2 1.6e-149 497.8 4.2 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFP12830.1 - 2e-29 101.1 34.1 4.8e-10 39.1 1.1 7.6 3 2 4 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KFP12830.1 - 1.4e-20 73.1 41.9 0.00027 21.3 0.2 9.8 7 3 3 11 11 11 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP12830.1 - 3.4e-09 36.7 9.4 3.8e-05 23.7 0.4 4.3 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP12830.1 - 8.3e-05 22.2 13.0 0.18 11.3 0.4 4.2 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 KFP12830.1 - 0.023 14.7 22.8 0.78 9.9 0.1 8.5 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 KFP12830.1 - 0.2 12.3 34.8 6 7.8 0.0 11.2 11 0 0 11 11 11 0 Leucine Rich Repeat Pannexin_like PF12534.8 KFP12831.1 - 3.7e-126 421.0 15.5 4.8e-126 420.6 15.5 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFP12831.1 - 1.5e-26 91.9 48.9 7.3e-11 41.7 3.8 7.6 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 KFP12831.1 - 1.8e-15 56.8 64.1 2.6e-05 24.5 0.2 9.7 5 2 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP12831.1 - 1.4e-08 34.8 18.4 0.00018 21.5 2.4 3.9 1 1 4 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP12831.1 - 6.5e-07 29.0 19.7 0.016 14.7 1.0 3.8 1 1 2 3 3 3 3 Leucine-rich repeat Aminotran_1_2 PF00155.21 KFP12832.1 - 3e-50 171.4 0.0 3.4e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFP12832.1 - 0.00017 20.3 0.0 0.00027 19.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SLC35F PF06027.12 KFP12832.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Solute carrier family 35 DUF4462 PF14692.6 KFP12833.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) TFIIB PF00382.19 KFP12834.1 - 7e-53 176.6 2.1 1.1e-25 89.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFP12834.1 - 2e-14 52.8 0.3 3.2e-14 52.2 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KFP12834.1 - 2.8e-09 36.8 0.0 7.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP12834.1 - 0.0016 18.5 0.4 0.07 13.2 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 KFP12834.1 - 0.0028 17.7 0.1 0.0079 16.2 0.1 1.7 1 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Sigma70_r4 PF04545.16 KFP12834.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Pkinase PF00069.25 KFP12835.1 - 1.2e-60 205.1 0.0 2.3e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12835.1 - 9.1e-39 133.3 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFP12835.1 - 9.2e-33 112.2 16.2 3.6e-17 62.2 8.0 2.4 2 0 0 2 2 2 2 Hr1 repeat Kinase-like PF14531.6 KFP12835.1 - 4.5e-07 29.5 0.0 3.4e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP12835.1 - 7.7e-05 21.8 0.1 0.00049 19.2 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Uds1 PF15456.6 KFP12835.1 - 0.0004 20.6 7.2 0.016 15.4 1.9 2.6 1 1 1 2 2 2 2 Up-regulated During Septation C2 PF00168.30 KFP12835.1 - 0.0091 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain PL48 PF15903.5 KFP12835.1 - 0.19 10.7 2.0 1.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 Fib_alpha PF08702.10 KFP12835.1 - 0.66 10.2 5.7 0.23 11.6 1.8 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LIM PF00412.22 KFP12837.1 - 4.6e-07 30.0 0.7 5.5e-07 29.7 0.7 1.1 1 0 0 1 1 1 1 LIM domain Sulfotransfer_2 PF03567.14 KFP12838.1 - 2.1e-41 142.5 0.5 2.7e-41 142.2 0.5 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KFP12838.1 - 0.00038 19.5 0.0 0.00054 19.0 0.0 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 KFP12838.1 - 0.0061 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain RAP PF08373.10 KFP12838.1 - 0.041 14.0 0.2 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 RAP domain DICT PF10069.9 KFP12838.1 - 0.074 12.8 0.5 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF2129 PF09902.9 KFP12838.1 - 0.19 11.8 1.5 0.31 11.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Sep15_SelM PF08806.11 KFP12840.1 - 1.3e-12 47.6 0.0 1.4e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain BAR PF03114.18 KFP12841.1 - 4.7e-70 235.9 4.6 6.7e-70 235.4 4.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFP12841.1 - 8.4e-11 41.6 0.0 2.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.9 KFP12841.1 - 2.7e-09 36.6 0.1 4.2e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP12841.1 - 3.4e-08 33.5 1.7 4.7e-08 33.0 1.7 1.3 1 1 0 1 1 1 1 BAR domain of APPL family SH3_2 PF07653.17 KFP12841.1 - 7.8e-08 31.9 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP12841.1 - 8e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain CLCA PF08434.11 KFP12842.1 - 4.4e-114 380.3 6.4 6.7e-114 379.7 6.4 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 KFP12842.1 - 3.8e-16 59.8 0.0 8.3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP12842.1 - 2.5e-14 53.8 0.0 5.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP12842.1 - 2e-10 40.9 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP12842.1 - 0.00012 21.6 0.2 0.00026 20.5 0.2 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CelD_N PF02927.14 KFP12842.1 - 0.13 13.2 0.1 9.9 7.1 0.1 2.8 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain CVNH PF08881.10 KFP12845.1 - 0.058 14.1 1.6 5.5 7.7 0.2 3.5 2 2 1 4 4 4 0 CVNH domain FPP PF05911.11 KFP12845.1 - 5.6 5.0 97.4 0.16 10.1 37.7 3.5 1 1 3 4 4 4 0 Filament-like plant protein, long coiled-coil zf-HIT PF04438.16 KFP12847.1 - 4.2e-05 23.3 13.5 4.2e-05 23.3 13.5 1.9 3 0 0 3 3 3 1 HIT zinc finger zf-B_box PF00643.24 KFP12847.1 - 1.9 8.7 9.3 4.8 7.4 9.3 1.7 1 0 0 1 1 1 0 B-box zinc finger Cys_knot PF00007.22 KFP12848.1 - 2.9e-16 59.6 13.0 2.9e-16 59.6 13.0 3.0 3 0 0 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFP12848.1 - 2e-10 40.8 12.5 2e-10 40.8 12.5 4.6 3 1 0 3 3 3 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFP12848.1 - 3.9e-05 23.8 7.4 3.9e-05 23.8 7.4 3.8 5 1 0 5 5 5 1 Thrombospondin type 1 domain Sclerostin PF05463.11 KFP12848.1 - 0.00019 21.2 4.5 0.00038 20.2 4.5 1.5 1 0 0 1 1 1 1 Sclerostin (SOST) Amidinotransf PF02274.17 KFP12849.1 - 6.5e-05 22.2 0.0 0.00014 21.0 0.0 1.6 1 1 0 1 1 1 1 Amidinotransferase DUF585 PF04522.12 KFP12849.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF585) TTRAP PF14203.6 KFP12849.1 - 0.56 10.2 3.0 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein CARD PF00619.21 KFP12851.1 - 7.1e-16 58.0 0.3 1.1e-15 57.4 0.3 1.2 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFP12851.1 - 0.003 17.5 0.1 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain TetR_C_8 PF14278.6 KFP12851.1 - 0.1 12.7 0.1 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region WD40 PF00400.32 KFP12852.1 - 0.00032 21.4 7.6 0.62 11.0 0.0 5.3 4 1 0 4 4 4 2 WD domain, G-beta repeat PKD_channel PF08016.12 KFP12853.1 - 2.7e-11 42.8 12.8 2.7e-11 42.8 12.8 1.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFP12853.1 - 0.0043 16.3 25.4 0.018 14.3 25.5 1.9 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFP12854.1 - 7.8e-11 41.3 10.1 1.2e-10 40.7 10.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFP12854.1 - 0.00023 20.5 18.9 0.00052 19.3 18.9 1.5 1 1 0 1 1 1 1 Ion transport protein DUF4522 PF15022.6 KFP12854.1 - 0.01 16.1 0.1 0.025 14.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Claudin_3 PF06653.11 KFP12854.1 - 5.6 6.9 19.0 7.9 6.4 0.1 3.4 3 0 0 3 3 3 0 Tight junction protein, Claudin-like 7tm_1 PF00001.21 KFP12855.1 - 6.2e-35 120.8 23.5 1e-34 120.1 23.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP12855.1 - 0.0018 18.1 16.7 0.0063 16.3 16.7 1.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP12855.1 - 0.0028 17.3 23.7 0.0053 16.4 22.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TMEM192 PF14802.6 KFP12855.1 - 0.36 9.9 5.0 0.11 11.6 1.7 1.7 2 0 0 2 2 2 0 TMEM192 family ADIP PF11559.8 KFP12857.1 - 1.5e-39 135.5 19.1 1.5e-39 135.5 19.1 4.2 2 1 3 5 5 5 1 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.11 KFP12857.1 - 0.09 12.7 0.9 14 5.6 0.0 2.9 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Sulfatase_C PF14707.6 KFP12857.1 - 0.17 12.6 0.2 0.17 12.6 0.2 3.2 2 1 2 4 4 4 0 C-terminal region of aryl-sulfatase DUF3775 PF12616.8 KFP12857.1 - 1.4 8.9 4.8 0.41 10.7 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3775) Glyco_hydro_18 PF00704.28 KFP12858.1 - 1.6e-34 120.1 0.4 2.1e-34 119.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SPATA1_C PF15743.5 KFP12859.1 - 2.4e-52 177.1 27.9 2.4e-52 177.1 27.9 2.0 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus DUF5133 PF17196.4 KFP12859.1 - 0.093 12.9 0.8 13 6.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF5133) Crl PF07417.12 KFP12859.1 - 0.28 11.2 3.1 0.62 10.1 1.9 2.2 1 1 1 2 2 2 0 Sigma factor-binding transcriptional regulator Crl G-gamma PF00631.22 KFP12862.1 - 3.9e-09 36.4 0.0 4.1e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain Brix PF04427.18 KFP12863.1 - 7.7e-24 84.9 0.1 9.5e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain DNase_II PF03265.15 KFP12864.1 - 3.4e-107 358.5 0.3 3.9e-107 358.3 0.3 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Uricase PF01014.18 KFP12865.1 - 4.6e-45 153.1 0.0 4.1e-26 91.8 0.0 2.0 2 0 0 2 2 2 2 Uricase zf-SCNM1 PF15803.5 KFP12865.1 - 0.0087 15.7 0.0 0.024 14.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 SAM_1 PF00536.30 KFP12866.1 - 8.6e-10 38.9 0.0 1.1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP12866.1 - 4.8e-05 23.4 0.0 7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP12866.1 - 8.2e-05 22.5 0.0 9.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.25 KFP12867.1 - 2.3e-73 246.8 0.0 2.9e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12867.1 - 5.7e-35 120.9 0.0 7.8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP12867.1 - 1.2e-08 34.7 0.0 2.8e-08 33.4 0.0 1.5 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP12867.1 - 0.021 13.8 0.3 0.053 12.5 0.1 1.6 1 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFP12867.1 - 0.067 13.1 0.1 1.9 8.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family TTL PF03133.15 KFP12868.1 - 3.2e-79 266.1 0.4 3.2e-79 266.1 0.4 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KFP12868.1 - 2.1e-07 30.5 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KFP12868.1 - 6e-07 29.0 3.6 0.001 18.3 0.0 3.4 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 KFP12868.1 - 0.00086 19.4 0.0 0.0033 17.5 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain GTP-bdg_M PF16360.5 KFP12868.1 - 0.07 13.7 8.5 0.039 14.6 4.6 2.6 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region RimK PF08443.11 KFP12868.1 - 0.097 12.3 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF4462 PF14692.6 KFP12870.1 - 0.2 11.2 0.4 0.54 9.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) DnaJ_C PF01556.18 KFP12874.1 - 8.7e-45 152.4 0.0 1.1e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFP12874.1 - 2.6e-12 46.9 17.9 4.6e-12 46.1 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KFP12874.1 - 0.013 15.5 7.1 0.15 12.1 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L32p PF01783.23 KFP12874.1 - 0.35 11.2 6.9 5.5 7.3 0.5 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 KFP12874.1 - 0.9 9.6 8.0 0.75 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons Anti-TRAP PF15777.5 KFP12874.1 - 2.8 8.0 14.9 6.7 6.7 1.7 3.5 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Filament PF00038.21 KFP12875.1 - 2.4e-36 125.9 37.3 2.9e-36 125.7 37.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 KFP12875.1 - 0.0087 15.4 15.1 0.0087 15.4 15.1 3.1 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 KFP12875.1 - 0.15 12.2 0.3 0.15 12.2 0.3 5.5 4 1 1 5 5 5 0 Basic region leucine zipper Peptidase_C58 PF03543.14 KFP12875.1 - 0.36 10.5 13.8 0.14 11.9 2.1 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF3037 PF11236.8 KFP12875.1 - 0.69 10.4 12.1 0.28 11.6 2.9 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3037) DUF3708 PF12501.8 KFP12875.1 - 3.5 7.4 5.8 1.2 8.9 1.1 2.0 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter YlqD PF11068.8 KFP12875.1 - 3.6 8.0 38.7 4.6 7.6 0.0 4.4 2 2 2 4 4 4 0 YlqD protein DUF4472 PF14739.6 KFP12875.1 - 3.8 8.3 38.0 3.4 8.4 5.8 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 KFP12875.1 - 4.3 7.4 15.3 2 8.5 0.0 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFP12875.1 - 7 5.9 23.0 5.4 6.3 10.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ammonium_transp PF00909.21 KFP12876.1 - 2.4e-49 168.1 16.7 3e-49 167.8 16.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1003 PF06210.11 KFP12876.1 - 0.0054 16.8 2.4 0.0054 16.8 2.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) Pkinase PF00069.25 KFP12877.1 - 8.2e-74 248.3 0.2 2.7e-73 246.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12877.1 - 1.3e-33 116.4 0.0 3.2e-33 115.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP12877.1 - 2.6e-07 29.9 0.1 2.6e-07 29.9 0.1 2.7 3 0 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 KFP12877.1 - 0.00029 20.2 0.0 0.0026 17.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Med1 PF10744.9 KFP12878.1 - 5.3e-65 220.1 0.0 2.6e-64 217.8 0.0 2.3 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 LRR_4 PF12799.7 KFP12879.1 - 2.2e-20 72.4 11.4 0.0075 16.7 0.4 6.5 6 0 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP12879.1 - 5.3e-19 66.6 24.5 0.0031 17.4 0.1 10.9 11 0 0 11 11 11 5 Leucine Rich repeat F-box-like PF12937.7 KFP12879.1 - 2.8e-13 49.5 0.6 1.1e-12 47.6 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP12879.1 - 2.7e-08 33.5 0.7 1.5e-07 31.1 0.7 2.4 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 KFP12879.1 - 1.8e-05 24.4 6.2 0.1 12.4 1.4 5.2 3 2 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 KFP12879.1 - 2.3e-05 24.3 24.1 8.5 7.4 0.2 9.8 10 2 0 10 10 10 3 Leucine Rich Repeat F-box_4 PF15966.5 KFP12879.1 - 0.0017 18.3 0.4 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 F-box Ribosomal_L19e PF01280.20 KFP12880.1 - 1e-65 220.2 12.9 1e-65 220.2 12.9 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e DUF1682 PF07946.14 KFP12880.1 - 4.6 6.4 15.4 5.8 6.0 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RAMP PF04901.13 KFP12881.1 - 4.2e-45 152.3 3.1 4.8e-45 152.1 3.1 1.0 1 0 0 1 1 1 1 Receptor activity modifying family DUF761 PF05553.11 KFP12881.1 - 0.12 11.9 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Cotton fibre expressed protein Longin PF13774.6 KFP12882.1 - 2.6e-13 49.8 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RVT_1 PF00078.27 KFP12883.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANKH PF07260.11 KFP12884.1 - 1.2e-200 665.9 5.1 1.7e-200 665.4 5.1 1.2 1 0 0 1 1 1 1 Progressive ankylosis protein (ANKH) UCR_Fe-S_N PF10399.9 KFP12884.1 - 0.85 9.0 0.0 0.85 9.0 0.0 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_C101 PF16218.5 KFP12885.1 - 5.2e-129 429.2 0.6 6e-129 429.0 0.6 1.0 1 0 0 1 1 1 1 Peptidase family C101 Peptidase_C65 PF10275.9 KFP12885.1 - 0.002 17.6 1.3 0.009 15.5 1.3 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C101 PF16218.5 KFP12886.1 - 2.8e-115 384.1 1.5 3.4e-115 383.9 1.5 1.1 1 0 0 1 1 1 1 Peptidase family C101 DHC_N1 PF08385.12 KFP12887.1 - 8e-178 592.6 14.7 8e-178 592.6 14.7 4.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFP12887.1 - 9.4e-146 484.9 0.0 1.2e-144 481.4 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP12887.1 - 3.2e-124 415.1 8.4 3.2e-124 415.1 8.4 4.0 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFP12887.1 - 2.5e-97 325.8 0.4 2.6e-96 322.5 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFP12887.1 - 1.3e-94 316.4 0.0 4.9e-94 314.5 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFP12887.1 - 2e-85 285.4 1.7 2e-85 285.4 1.7 4.3 6 0 0 6 6 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFP12887.1 - 1.1e-70 236.8 0.1 1.1e-63 214.0 0.0 3.9 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFP12887.1 - 3.7e-55 186.2 0.3 9.8e-55 184.8 0.3 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFP12887.1 - 3.6e-44 151.2 13.4 9.9e-44 149.8 13.4 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFP12887.1 - 1.2e-42 144.7 1.1 1.2e-40 138.3 0.0 3.8 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KFP12887.1 - 1.3e-21 77.1 0.0 1.4e-06 28.3 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFP12887.1 - 1.7e-19 69.9 0.0 7.8e-19 67.7 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KFP12887.1 - 6.6e-19 68.3 0.1 1.4e-17 64.0 0.1 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KFP12887.1 - 7.4e-06 26.4 0.0 2.4 8.6 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP12887.1 - 0.00014 22.3 0.3 3.1 8.2 0.0 5.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KFP12887.1 - 0.00066 20.0 0.6 19 5.5 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFP12887.1 - 0.067 12.9 4.5 21 4.8 0.3 4.2 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KFP12887.1 - 0.097 12.0 0.1 0.79 9.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KFP12887.1 - 0.16 12.2 0.0 6.4 6.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain LOH1CR12 PF10158.9 KFP12887.1 - 1 9.4 6.2 2.5 8.1 0.3 4.0 3 0 0 3 3 2 0 Tumour suppressor protein AAA_19 PF13245.6 KFP12887.1 - 3.4 8.0 10.2 49 4.2 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KFP12887.1 - 5.6 7.5 10.3 14 6.2 0.0 4.6 5 0 0 5 5 3 0 ABC transporter zf-H2C2_2 PF13465.6 KFP12888.1 - 4.7e-44 146.9 41.8 8.1e-10 38.7 0.9 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP12888.1 - 2.6e-37 125.2 42.8 1.2e-06 28.6 0.5 8.1 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP12888.1 - 2.2e-21 74.7 38.1 0.00026 21.5 0.4 7.1 7 0 0 7 7 6 6 C2H2-type zinc finger zf_UBZ PF18439.1 KFP12888.1 - 1.2e-14 53.5 12.9 0.036 13.7 0.0 6.2 6 0 0 6 6 6 6 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP12888.1 - 1.5e-10 41.0 19.6 0.00086 19.4 1.0 4.7 3 2 2 5 5 5 3 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP12888.1 - 7.8e-10 38.8 5.2 0.0096 16.2 0.1 6.0 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP12888.1 - 1.1e-08 34.8 33.7 0.00011 22.1 0.2 7.0 7 0 0 7 7 6 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFP12888.1 - 4.5e-08 32.9 15.5 0.13 12.2 0.2 6.0 6 0 0 6 6 6 2 LYAR-type C2HC zinc finger zinc_ribbon_15 PF17032.5 KFP12888.1 - 2.9e-07 31.1 8.3 0.12 13.1 0.5 3.3 1 1 2 3 3 3 3 zinc-ribbon family zf-C2H2_11 PF16622.5 KFP12888.1 - 7.5e-07 28.8 14.8 1.5 8.7 0.1 6.3 6 0 0 6 6 6 2 zinc-finger C2H2-type DZR PF12773.7 KFP12888.1 - 8.5e-07 28.9 14.8 50 4.0 14.8 3.8 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.12 KFP12888.1 - 8.6e-07 29.1 15.0 0.037 14.2 1.8 5.0 1 1 5 6 6 6 3 TFIIH C1-like domain CpXC PF14353.6 KFP12888.1 - 1.9e-06 27.9 12.7 0.6 10.2 0.0 5.7 2 1 3 6 6 6 2 CpXC protein HypA PF01155.19 KFP12888.1 - 5.8e-06 26.3 8.5 0.24 11.4 1.2 3.4 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 KFP12888.1 - 2e-05 24.8 15.7 1.1 9.8 0.0 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type XPA_N PF01286.18 KFP12888.1 - 2.9e-05 24.0 17.7 2 8.5 0.3 6.0 6 0 0 6 6 6 2 XPA protein N-terminal zinc_ribbon_4 PF13717.6 KFP12888.1 - 3.7e-05 23.5 12.3 4.9 7.2 0.1 6.0 6 0 0 6 6 6 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KFP12888.1 - 5.6e-05 23.0 22.0 0.001 18.9 0.7 4.6 4 1 0 4 4 3 2 SprT-like zinc ribbon domain zf-AN1 PF01428.16 KFP12888.1 - 0.00013 22.0 21.0 2.9 8.1 0.1 6.3 6 0 0 6 6 6 1 AN1-like Zinc finger zf-trcl PF13451.6 KFP12888.1 - 0.00016 21.5 15.0 3.7 7.5 0.1 6.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain Zn_ribbon_recom PF13408.6 KFP12888.1 - 0.00034 21.1 22.9 0.74 10.4 0.7 5.4 2 2 4 6 6 6 1 Recombinase zinc beta ribbon domain FYDLN_acid PF09538.10 KFP12888.1 - 0.00045 20.8 11.0 3.4 8.4 0.1 5.3 2 2 3 5 5 5 1 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.13 KFP12888.1 - 0.00096 18.8 24.9 2.5 7.8 0.1 6.2 6 0 0 6 6 6 2 DNA directed RNA polymerase, 7 kDa subunit zf-Di19 PF05605.12 KFP12888.1 - 0.0034 17.6 15.2 0.3 11.4 0.2 4.1 1 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding YhfH PF14149.6 KFP12888.1 - 0.0054 16.7 19.8 3.8 7.6 0.1 6.0 6 0 0 6 6 6 0 YhfH-like protein Evr1_Alr PF04777.13 KFP12888.1 - 0.012 16.1 14.1 2.1 8.9 0.9 4.9 1 1 2 4 4 4 0 Erv1 / Alr family ADK_lid PF05191.14 KFP12888.1 - 0.03 14.3 19.0 0.49 10.4 2.1 5.4 3 2 2 5 5 5 0 Adenylate kinase, active site lid Yippee-Mis18 PF03226.14 KFP12888.1 - 0.075 13.3 4.1 12 6.2 2.2 3.4 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_5 PF13719.6 KFP12888.1 - 0.15 11.8 15.6 22 4.9 0.0 5.9 6 0 0 6 6 6 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFP12888.1 - 0.15 12.0 15.4 41 4.3 3.9 4.7 1 1 1 2 2 2 0 zinc-ribbons zf-RING_5 PF14634.6 KFP12888.1 - 0.25 11.3 14.1 7 6.7 1.1 4.6 3 2 1 4 4 4 0 zinc-RING finger domain ArfGap PF01412.18 KFP12888.1 - 0.3 11.2 7.6 2.1 8.5 1.0 4.0 3 1 1 4 4 4 0 Putative GTPase activating protein for Arf zinc_ribbon_9 PF14369.6 KFP12888.1 - 0.33 11.2 19.0 9.1 6.6 0.1 5.5 6 0 0 6 6 6 0 zinc-ribbon DUF3268 PF11672.8 KFP12888.1 - 0.48 10.8 13.6 2.5 8.4 0.3 4.0 1 1 3 5 5 5 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 KFP12888.1 - 0.66 10.0 0.1 0.66 10.0 0.1 4.6 4 2 0 4 4 4 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KFP12888.1 - 0.8 9.8 6.2 4.7 7.3 0.8 3.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain GAGA PF09237.11 KFP12888.1 - 0.85 9.5 8.0 1.5 8.7 0.5 3.4 2 2 2 4 4 4 0 GAGA factor TFIIS_C PF01096.18 KFP12888.1 - 1 9.2 27.3 6.3 6.7 0.1 6.6 7 0 0 7 7 7 0 Transcription factor S-II (TFIIS) Ribosomal_L37ae PF01780.19 KFP12888.1 - 1.2 9.2 16.5 28 4.9 0.3 5.0 2 2 2 5 5 5 0 Ribosomal L37ae protein family LIM PF00412.22 KFP12888.1 - 1.3 9.3 21.9 14 6.0 0.6 5.3 1 1 5 6 6 6 0 LIM domain zf-C2H2_3rep PF18868.1 KFP12888.1 - 1.6 9.4 13.4 6 7.6 0.7 4.5 1 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFP12888.1 - 2 8.3 6.2 2.2e+02 1.8 0.0 4.7 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFP12888.1 - 2.1 8.9 8.1 11 6.6 0.0 3.9 5 0 0 5 5 2 0 Autophagy receptor zinc finger-C2H2 domain zf-HYPF PF07503.12 KFP12888.1 - 2.9 7.7 20.7 4.3 7.2 1.8 5.4 5 1 0 5 5 5 0 HypF finger IBR PF01485.21 KFP12888.1 - 3.8 7.8 20.4 2.8 8.3 1.2 4.1 1 1 3 4 4 4 0 IBR domain, a half RING-finger domain DUF2321 PF10083.9 KFP12888.1 - 4 7.1 14.2 0.089 12.4 0.7 3.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Rubredoxin_2 PF18073.1 KFP12888.1 - 6.1 6.7 34.5 0.76 9.6 2.2 6.5 6 0 0 6 6 6 0 Rubredoxin metal binding domain zf-Mss51 PF13824.6 KFP12888.1 - 6.3 7.0 33.6 1.1 9.4 0.7 5.9 2 2 2 4 4 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_7 PF02591.15 KFP12888.1 - 7.3 6.9 22.3 12 6.2 0.1 5.4 6 0 0 6 6 5 0 C4-type zinc ribbon domain zf_C2H2_13 PF18508.1 KFP12888.1 - 9 6.0 13.8 44 3.8 0.0 5.4 6 0 0 6 6 6 0 Zinc finger domain DNA_topoisoIV PF00521.20 KFP12889.1 - 6.9e-134 446.9 0.3 1.3e-133 446.0 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFP12889.1 - 2.4e-49 166.9 4.5 2.4e-49 166.9 4.5 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DTHCT PF08070.11 KFP12889.1 - 1.2e-27 96.7 17.5 1.2e-27 96.7 17.5 6.5 4 1 2 6 6 6 1 DTHCT (NUC029) region DNA_gyraseB PF00204.25 KFP12889.1 - 2.1e-24 85.9 0.6 5.4e-24 84.6 0.6 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFP12889.1 - 3.7e-15 56.4 0.0 1.5e-14 54.5 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFP12889.1 - 3.6e-09 36.8 0.0 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain PAW PF04721.17 KFP12890.1 - 6.7e-72 241.4 1.0 1.3e-71 240.5 1.0 1.5 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Transglut_core PF01841.19 KFP12890.1 - 3.3e-16 59.7 0.9 9.2e-16 58.3 0.9 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily PUB PF09409.10 KFP12890.1 - 2.2e-14 53.1 0.8 1e-13 51.0 0.0 2.7 3 0 0 3 3 3 1 PUB domain Rad4 PF03835.15 KFP12890.1 - 6.4e-11 42.1 0.6 1.3e-10 41.2 0.6 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain FTCD_N PF07837.12 KFP12890.1 - 0.033 14.0 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain ketoacyl-synt PF00109.26 KFP12891.1 - 2.5e-55 187.8 2.1 2.5e-55 187.8 2.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFP12891.1 - 4e-38 130.1 0.1 8.2e-38 129.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFP12891.1 - 2.2e-05 24.0 0.1 7.8e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFP12891.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension LRR_8 PF13855.6 KFP12892.1 - 2.2e-17 62.5 3.3 1.7e-11 43.7 0.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 KFP12892.1 - 6.2e-09 35.3 3.0 6.2e-09 35.3 3.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KFP12892.1 - 5.5e-08 33.0 8.5 2.5e-05 24.5 0.6 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP12892.1 - 2.7e-06 27.4 0.1 4.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KFP12892.1 - 0.00029 20.6 2.2 0.2 11.8 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KFP12892.1 - 0.00038 20.6 8.3 0.23 12.1 0.2 4.4 4 2 0 4 4 4 2 Leucine Rich Repeat Pkinase PF00069.25 KFP12893.1 - 3.9e-30 105.1 1.0 3.9e-30 105.1 1.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP12893.1 - 3.7e-21 75.6 0.2 6.5e-21 74.8 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP12893.1 - 0.00021 21.3 0.1 0.0011 18.9 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Arm PF00514.23 KFP12893.1 - 0.00055 19.9 11.4 0.02 14.9 0.5 4.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat RIO1 PF01163.22 KFP12893.1 - 0.0009 18.9 0.1 0.0019 17.8 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFP12893.1 - 0.0031 16.3 0.1 0.0031 16.3 0.1 2.2 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP12893.1 - 0.0049 15.9 1.6 0.0049 15.9 1.6 1.8 2 0 0 2 2 2 1 Haspin like kinase domain TraD PF06412.11 KFP12893.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TraD FOXO_KIX_bdg PF16675.5 KFP12893.1 - 0.15 12.4 1.5 0.46 10.8 1.5 1.8 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 HCO3_cotransp PF00955.21 KFP12894.1 - 3.6e-206 685.9 5.6 4.2e-206 685.7 5.6 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP12894.1 - 1.5e-107 359.4 0.0 2.5e-107 358.7 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain NO_synthase PF02898.15 KFP12894.1 - 0.13 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain Rab5ip PF07019.12 KFP12894.1 - 2.5 8.7 6.7 8 7.1 0.4 3.0 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) T-box_assoc PF16176.5 KFP12895.1 - 9.6e-110 366.0 2.5 1.2e-109 365.6 2.5 1.1 1 0 0 1 1 1 1 T-box transcription factor-associated T-box PF00907.22 KFP12895.1 - 9.5e-63 211.8 0.2 1.6e-62 211.0 0.2 1.4 1 0 0 1 1 1 1 T-box Cmc1 PF08583.10 KFP12896.1 - 7.1e-16 58.0 5.0 9.5e-16 57.6 5.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Colipase PF01114.18 KFP12896.1 - 0.018 14.7 1.4 0.028 14.1 1.4 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain NDUF_B7 PF05676.13 KFP12896.1 - 0.038 13.7 1.3 0.038 13.7 1.3 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 KFP12896.1 - 0.22 12.0 5.2 0.37 11.2 5.0 1.5 1 1 0 1 1 1 0 GCK domain CHCH PF06747.13 KFP12896.1 - 1.7 8.9 8.9 8.2 6.7 1.8 2.6 3 0 0 3 3 3 0 CHCH domain TBD PF12845.7 KFP12897.1 - 4.7e-17 61.6 0.1 4.7e-17 61.6 0.1 3.7 4 0 0 4 4 4 1 TBD domain Speriolin_N PF15058.6 KFP12897.1 - 0.019 15.0 1.6 0.038 14.1 1.6 1.6 1 0 0 1 1 1 0 Speriolin N terminus RRM_Rrp7 PF17799.1 KFP12897.1 - 0.089 12.6 8.2 1.1 9.1 7.5 2.9 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Cob_adeno_trans PF01923.18 KFP12897.1 - 0.22 11.6 7.0 0.1 12.7 4.2 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF3037 PF11236.8 KFP12897.1 - 0.84 10.1 5.6 5.1 7.5 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) FUSC-like PF12805.7 KFP12897.1 - 0.85 8.6 8.5 1.4 8.0 8.5 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DivIC PF04977.15 KFP12897.1 - 0.95 9.3 0.0 0.95 9.3 0.0 4.5 4 1 1 5 5 5 0 Septum formation initiator Cnn_1N PF07989.11 KFP12897.1 - 2.3 8.4 28.8 2.6 8.3 11.6 4.1 1 1 1 2 2 1 0 Centrosomin N-terminal motif 1 DUF3800 PF12686.7 KFP12897.1 - 4 8.1 8.0 1.5e+02 3.0 8.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Prefoldin_2 PF01920.20 KFP12897.1 - 5 7.1 34.8 2 8.4 7.6 4.0 3 1 1 4 4 4 0 Prefoldin subunit Neur_chan_memb PF02932.16 KFP12897.1 - 6.2 6.8 7.7 11 6.0 7.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.14 KFP12897.1 - 9.3 6.6 31.0 1.3 9.3 12.5 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 KFP12898.1 - 2.1e-32 110.8 0.0 1.9e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP12898.1 - 0.015 15.5 0.0 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_7 PF16367.5 KFP12898.1 - 0.019 15.1 0.0 9.7 6.4 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Es2 PF09751.9 KFP12898.1 - 0.052 13.3 0.1 0.052 13.3 0.1 2.2 2 0 0 2 2 2 0 Nuclear protein Es2 ecTbetaR2 PF08917.10 KFP12899.1 - 1.4e-42 144.1 16.0 3.8e-42 142.7 16.0 1.7 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr PF07714.17 KFP12899.1 - 6.6e-36 123.9 0.0 1.2e-35 123.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12899.1 - 1.7e-33 116.1 0.0 2.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFP12899.1 - 0.015 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP12899.1 - 0.02 13.9 0.9 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFP12899.1 - 0.02 14.8 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FixQ PF05545.11 KFP12899.1 - 0.086 12.8 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Sigma_reg_N PF13800.6 KFP12899.1 - 0.16 12.2 0.2 0.42 10.9 0.2 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Pyridoxal_deC PF00282.19 KFP12900.1 - 1.6e-116 389.1 0.0 1.9e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFP12900.1 - 1.6e-06 27.4 0.0 9.1e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP12900.1 - 0.0002 20.8 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 KFP12900.1 - 0.028 13.1 0.0 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS STT3 PF02516.14 KFP12901.1 - 2.2e-135 452.4 38.8 4.8e-132 441.3 33.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit TMEM220 PF15071.6 KFP12901.1 - 0.32 11.8 0.1 0.32 11.8 0.1 3.5 3 2 0 3 3 3 0 Transmembrane family 220, helix Oxysterol_BP PF01237.18 KFP12902.1 - 4e-85 285.9 3.4 2.1e-83 280.2 3.4 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KFP12902.1 - 2e-08 34.4 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP12902.1 - 2.7e-07 31.1 0.0 7.9e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 KFP12902.1 - 0.0076 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 KFP12902.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 PH domain PH_13 PF16652.5 KFP12902.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain NAD_Gly3P_dh_C PF07479.14 KFP12903.1 - 1.2e-50 171.5 0.4 2.4e-50 170.5 0.4 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFP12903.1 - 8.1e-46 155.8 0.6 1.3e-45 155.1 0.2 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MARVEL PF01284.23 KFP12904.1 - 1.1e-14 54.7 18.9 1.2e-14 54.5 18.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF5367 PF17329.2 KFP12904.1 - 0.14 12.3 7.6 0.21 11.8 7.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5367) TMEM138 PF14935.6 KFP12904.1 - 0.15 12.7 9.9 0.68 10.6 2.5 2.0 1 1 1 2 2 2 0 Transmembrane protein 138 Retrotran_gag_3 PF14244.6 KFP12904.1 - 0.22 11.3 1.3 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type HRG PF16954.5 KFP12904.1 - 7.3 7.1 21.5 0.35 11.3 7.1 3.1 2 1 1 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene MARVEL PF01284.23 KFP12905.1 - 2.4e-08 34.1 14.4 4.7e-08 33.2 14.4 1.5 1 1 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.11 KFP12905.1 - 9.2 5.3 8.5 9.8 5.3 8.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PhoR PF11808.8 KFP12905.1 - 9.6 6.7 8.7 38 4.8 0.1 2.6 1 1 2 3 3 3 0 Phosphate regulon sensor protein PhoR DLIC PF05783.11 KFP12906.1 - 5.1e-245 813.6 0.0 6e-245 813.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 KFP12906.1 - 0.04 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TPR_1 PF00515.28 KFP12907.1 - 6.4e-15 54.3 15.3 2.1e-05 24.2 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP12907.1 - 1.5e-13 49.7 25.6 0.00097 19.1 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP12907.1 - 3.5e-08 33.6 16.4 0.024 14.9 0.3 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP12907.1 - 9.5e-07 29.2 17.2 1.5 9.4 0.0 9.1 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP12907.1 - 3.7e-06 26.7 12.1 0.001 19.1 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP12907.1 - 1.4e-05 24.8 2.3 0.024 14.6 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP12907.1 - 1.4e-05 25.5 5.2 12 7.1 0.0 7.4 8 1 1 9 9 8 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFP12907.1 - 2.4e-05 24.3 4.1 0.059 13.4 0.3 3.7 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_17 PF13431.6 KFP12907.1 - 0.00065 19.9 11.1 4.7 7.8 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP12907.1 - 0.001 18.9 2.9 1.3 9.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP12907.1 - 0.0019 18.4 25.5 3.1 8.1 0.4 7.5 7 2 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KFP12907.1 - 0.015 14.7 4.4 1 8.7 0.0 3.0 3 0 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 KFP12907.1 - 0.03 15.0 0.2 5.3 7.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat BLOC1_2 PF10046.9 KFP12907.1 - 0.081 13.2 2.9 0.57 10.5 2.9 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KFP12907.1 - 0.23 11.7 1.3 0.89 9.9 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_11 PF13414.6 KFP12907.1 - 0.76 9.5 5.3 8.7 6.1 0.0 4.8 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 KFP12907.1 - 0.93 10.3 8.9 28 5.6 0.0 6.0 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF4461 PF14688.6 KFP12908.1 - 3.6e-124 414.6 1.3 6e-124 413.8 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 KFP12908.1 - 5e-39 132.8 0.1 1.5e-38 131.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) YkyA PF10368.9 KFP12908.1 - 0.057 13.1 0.9 0.22 11.2 0.9 2.0 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Asp_Glu_race_2 PF14669.6 KFP12909.1 - 2.1e-93 310.8 0.1 5.8e-93 309.4 0.1 1.8 1 0 0 1 1 1 1 Putative aspartate racemase PPR PF01535.20 KFP12909.1 - 0.012 15.8 1.4 27 5.3 0.0 5.8 8 0 0 8 8 8 0 PPR repeat Bunya_RdRp PF04196.12 KFP12910.1 - 0.0089 14.5 0.6 0.0099 14.3 0.6 1.0 1 0 0 1 1 1 1 Bunyavirus RNA dependent RNA polymerase Asp PF00026.23 KFP12911.1 - 3e-88 296.3 3.1 1e-69 235.4 2.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP12911.1 - 2.3e-17 63.8 1.4 2.4e-15 57.2 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFP12911.1 - 0.097 12.4 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Mod_r PF07200.13 KFP12912.1 - 1.1e-34 119.7 21.1 1.6e-34 119.1 21.1 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RNA_pol_Rpb2_3 PF04565.16 KFP12912.1 - 0.019 15.1 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 Methyltransf_14 PF08484.11 KFP12912.1 - 0.054 13.3 0.2 0.089 12.6 0.1 1.4 1 1 0 1 1 1 0 C-methyltransferase C-terminal domain zf-C4H2 PF10146.9 KFP12912.1 - 0.089 13.1 5.8 0.11 12.8 5.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2703 PF10865.8 KFP12912.1 - 1.9 8.7 5.6 0.27 11.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Atg14 PF10186.9 KFP12912.1 - 7 5.6 12.2 8.9 5.3 12.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Methyltransf_15 PF09445.10 KFP12913.1 - 9.9e-37 126.1 0.1 1.7e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KFP12913.1 - 9.8e-08 32.6 0.0 2.8e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFP12913.1 - 3.8e-07 30.1 0.0 7.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 KFP12913.1 - 4.4e-07 29.8 1.1 1.5e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 KFP12913.1 - 1.7e-06 27.9 0.1 4.9e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP12913.1 - 6.9e-05 23.4 0.1 0.00018 22.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP12913.1 - 0.0025 17.5 1.8 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KFP12913.1 - 0.0039 17.1 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFP12913.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 KFP12913.1 - 0.0066 16.2 0.0 0.0066 16.2 0.0 2.7 2 2 0 2 2 2 1 DNA methylase PrmA PF06325.13 KFP12913.1 - 0.014 14.8 0.3 0.014 14.8 0.3 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) WASH-7_mid PF14744.6 KFP12913.1 - 8.2 5.4 7.8 2.9 6.9 0.6 2.1 2 0 0 2 2 2 0 WASH complex subunit 7 Acyltransferase PF01553.21 KFP12914.1 - 0.042 13.5 0.0 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Acyltransferase DUF1356 PF07092.12 KFP12914.1 - 0.58 9.4 2.6 0.81 8.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) HIT PF01230.23 KFP12915.1 - 1.6e-16 60.8 0.0 1.9e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFP12915.1 - 0.0079 16.7 0.0 0.01 16.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.7 KFP12917.1 - 6.7e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like BTK PF00779.19 KFP12917.1 - 0.0025 17.6 1.2 0.0025 17.6 1.2 1.9 2 0 0 2 2 2 1 BTK motif F-box PF00646.33 KFP12917.1 - 0.0095 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain Gal-bind_lectin PF00337.22 KFP12918.1 - 3.8e-36 123.6 0.0 5e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin MISS PF15822.5 KFP12919.1 - 1.1e-98 329.9 118.3 1.2e-98 329.7 118.3 1.0 1 0 0 1 1 1 1 MAPK-interacting and spindle-stabilising protein-like DUF4462 PF14692.6 KFP12920.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) SOCS PF12610.8 KFP12921.1 - 5.9e-20 71.4 2.7 1.7e-19 70.0 2.7 1.8 1 0 0 1 1 1 1 Suppressor of cytokine signalling SOCS_box PF07525.16 KFP12921.1 - 1.2e-10 41.5 0.1 2.4e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.24 KFP12921.1 - 2.5e-08 33.9 0.0 7.7e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 SH2 domain Mcl1_mid PF12341.8 KFP12922.1 - 5.9e-98 327.9 0.0 1.4e-97 326.6 0.0 1.7 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFP12922.1 - 3.2e-21 75.2 8.7 4.2e-07 30.5 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP12922.1 - 2.5e-10 40.5 0.8 0.00015 22.0 0.1 4.4 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HMG_box PF00505.19 KFP12922.1 - 2.8e-08 34.0 0.0 7.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box eIF2A PF08662.11 KFP12922.1 - 3.6e-05 23.7 0.0 0.0011 18.9 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HMG_box_2 PF09011.10 KFP12922.1 - 0.0016 19.0 0.1 0.0055 17.3 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain Hira PF07569.11 KFP12922.1 - 0.077 12.7 0.3 21 4.8 0.1 2.9 2 0 0 2 2 2 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KFP12922.1 - 0.32 9.9 2.7 12 4.7 0.1 3.4 3 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3734 PF12536.8 KFP12922.1 - 2.8 8.3 4.7 2.4 8.5 0.9 2.7 3 0 0 3 3 3 0 Patatin phospholipase GTP_cyclohydroI PF01227.22 KFP12923.1 - 1.1e-63 214.0 0.5 1.2e-63 213.7 0.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFP12923.1 - 0.00066 19.8 0.0 0.0014 18.8 0.0 1.5 1 1 0 1 1 1 1 QueF-like protein MAPKK1_Int PF08923.10 KFP12923.1 - 0.038 13.8 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting SAM_1 PF00536.30 KFP12924.1 - 7.6e-09 35.9 0.1 1.5e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHAT PF09246.10 KFP12924.1 - 0.00011 22.0 0.1 0.074 12.9 0.0 3.0 3 0 0 3 3 3 2 PHAT SAM_2 PF07647.17 KFP12924.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 KFP12925.1 - 9.9e-12 44.5 10.9 2.5e-11 43.3 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP12925.1 - 0.00013 21.8 10.7 0.00041 20.2 10.7 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DUF4462 PF14692.6 KFP12926.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) CDKN3 PF05706.12 KFP12927.1 - 7.6e-83 276.2 0.4 8.9e-83 276.0 0.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KFP12927.1 - 6.8e-07 29.1 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP12927.1 - 4.8e-05 23.2 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ANF_receptor PF01094.28 KFP12927.1 - 0.047 12.8 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region PTPlike_phytase PF14566.6 KFP12927.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate TGFb_propeptide PF00688.18 KFP12928.1 - 6.7e-54 183.2 0.9 9e-54 182.8 0.9 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP12928.1 - 6.2e-34 117.1 0.5 1.3e-33 116.1 0.5 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Tnp_DNA_bind PF14706.6 KFP12928.1 - 0.048 13.5 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Transposase DNA-binding DDHD PF02862.17 KFP12930.1 - 2.2e-49 168.6 0.0 4.9e-49 167.5 0.0 1.6 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 KFP12930.1 - 0.078 12.5 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF4462 PF14692.6 KFP12931.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP12932.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ig_3 PF13927.6 KFP12933.1 - 5e-28 97.5 3.7 3.7e-13 49.9 0.0 3.6 4 0 0 4 4 3 3 Immunoglobulin domain I-set PF07679.16 KFP12933.1 - 1.4e-23 82.7 0.0 1.2e-10 41.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP12933.1 - 1.7e-21 76.4 0.1 3.9e-09 36.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP12933.1 - 3.9e-21 75.0 0.1 9.8e-08 32.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFP12933.1 - 1.6e-16 60.1 3.6 4.6e-15 55.4 0.0 2.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP12933.1 - 9e-14 51.6 0.3 0.0034 17.5 0.0 4.2 3 1 1 4 4 4 3 Immunoglobulin V-set domain C1-set PF07654.15 KFP12933.1 - 4.1e-10 39.9 0.1 4.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFP12933.1 - 5.9e-07 29.8 0.0 0.027 14.8 0.0 3.2 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP12933.1 - 8.1e-06 26.0 0.0 0.051 13.8 0.0 3.5 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP12933.1 - 0.00028 20.9 0.0 1.8 8.7 0.0 3.2 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain BPD_transp_1 PF00528.22 KFP12933.1 - 0.096 12.4 1.6 0.14 11.9 1.6 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Vg_Tdu PF07545.14 KFP12934.1 - 3.5e-20 71.5 0.4 5.2e-20 70.9 0.4 1.3 1 0 0 1 1 1 1 Vestigial/Tondu family HNOB PF07700.15 KFP12934.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding Snf7 PF03357.21 KFP12935.1 - 1.3e-43 148.5 29.1 1.3e-43 148.5 29.1 1.4 2 0 0 2 2 2 1 Snf7 DnaJ-X PF14308.6 KFP12935.1 - 0.00024 20.6 13.5 0.00024 20.6 13.5 1.6 1 1 1 2 2 2 1 X-domain of DnaJ-containing UCH PF00443.29 KFP12935.1 - 0.078 12.5 4.5 0.094 12.2 4.5 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3585 PF12130.8 KFP12935.1 - 0.4 10.8 13.4 1.2 9.3 13.3 1.9 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Imm42 PF15593.6 KFP12935.1 - 4.4 7.8 8.1 25 5.3 8.1 2.0 1 1 0 1 1 1 0 Immunity protein 42 SICA_beta PF12878.7 KFP12935.1 - 5.2 7.2 14.2 16 5.7 14.2 1.8 1 1 0 1 1 1 0 SICA extracellular beta domain Pou PF00157.17 KFP12936.1 - 1.1e-34 118.3 3.3 7.9e-34 115.5 0.4 3.1 3 0 0 3 3 3 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP12936.1 - 1e-17 63.7 2.1 1e-17 63.7 2.1 1.8 2 0 0 2 2 2 1 Homeodomain HTH_31 PF13560.6 KFP12936.1 - 0.059 13.7 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 KFP12936.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain Lsr2 PF11774.8 KFP12936.1 - 0.18 12.0 0.9 0.32 11.1 0.2 1.7 2 0 0 2 2 2 0 Lsr2 7tm_1 PF00001.21 KFP12937.1 - 4.5e-76 255.6 10.0 6.2e-76 255.2 10.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP12937.1 - 1.2e-07 31.4 16.3 6.3e-07 29.0 16.3 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP12937.1 - 4.1e-05 23.3 14.0 4.1e-05 23.3 14.0 2.2 2 2 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx PDZ PF00595.24 KFP12938.1 - 5.3e-55 183.7 9.5 8.4e-14 51.7 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP12938.1 - 1.7e-49 165.5 9.4 1.5e-13 50.3 0.5 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP12938.1 - 4e-34 116.8 8.3 1.5e-08 34.9 0.4 4.3 4 0 0 4 4 4 4 PDZ domain GRASP55_65 PF04495.14 KFP12938.1 - 4.7e-10 39.9 1.2 0.038 14.3 0.0 4.1 3 1 1 4 4 4 3 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 KFP12938.1 - 5e-07 29.6 4.2 0.02 14.8 0.1 4.4 4 0 0 4 4 4 2 Tricorn protease PDZ domain DUF3394 PF11874.8 KFP12938.1 - 0.00029 20.5 0.6 8.3 6.0 0.0 4.2 3 2 0 4 4 4 2 Domain of unknown function (DUF3394) DUF4265 PF14085.6 KFP12938.1 - 0.0032 17.4 0.2 0.012 15.6 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4265) DUF1450 PF07293.11 KFP12938.1 - 0.16 11.8 2.7 9.8 6.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1450) DUF4154 PF13689.6 KFP12938.1 - 0.2 11.9 0.8 0.63 10.3 0.1 2.2 3 0 0 3 3 3 0 YfiR/HmsC-like DUF5354 PF17305.2 KFP12938.1 - 0.25 11.6 4.8 0.37 11.0 0.0 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5354) ABA_GPCR PF12430.8 KFP12939.1 - 5.1e-42 143.7 12.4 5.1e-42 143.7 12.4 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFP12939.1 - 7.9e-29 99.5 0.4 2.1e-28 98.2 0.1 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal NPCC PF08058.11 KFP12939.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.4 3 1 0 3 3 3 0 Nuclear pore complex component DUF1772 PF08592.11 KFP12939.1 - 9.3 6.6 7.0 10 6.4 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Connexin PF00029.19 KFP12940.1 - 5.1e-101 337.3 0.1 5.1e-101 337.3 0.1 1.9 2 0 0 2 2 2 1 Connexin Connexin50 PF03509.14 KFP12940.1 - 1e-29 103.1 2.4 2.7e-29 101.8 0.3 2.5 2 0 0 2 2 2 1 Gap junction alpha-8 protein (Cx50) His_Phos_2 PF00328.22 KFP12941.1 - 9.3e-20 71.3 0.1 1e-18 67.9 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BCL9 PF11502.8 KFP12942.1 - 1.6e-20 72.6 2.0 6.2e-20 70.7 2.0 2.1 1 0 0 1 1 1 1 B-cell lymphoma 9 protein Glyco_transf_90 PF05686.12 KFP12943.1 - 1.9e-113 379.4 1.1 2.3e-113 379.1 1.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KFP12943.1 - 0.045 14.2 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 GST_C PF00043.25 KFP12943.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tim17 PF02466.19 KFP12944.1 - 9.7e-09 35.6 2.5 1.5e-08 35.0 2.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 KFP12944.1 - 3.4 7.9 9.6 6.4 7.0 8.5 2.0 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide V-set PF07686.17 KFP12946.1 - 1.9e-09 37.7 0.8 3.1e-09 37.0 0.1 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP12946.1 - 7.5e-09 35.6 0.3 1.5e-08 34.6 0.1 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFP12946.1 - 2.8e-06 27.8 3.7 0.0014 19.2 0.1 3.2 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP12946.1 - 0.00059 19.9 0.0 0.0031 17.6 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP12946.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP12946.1 - 0.0025 17.9 0.1 0.017 15.3 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP12946.1 - 0.0027 18.0 3.7 0.31 11.4 0.1 3.4 2 2 1 3 3 3 1 Immunoglobulin domain SPT_ssu-like PF11779.8 KFP12946.1 - 0.0044 16.6 0.2 0.0093 15.6 0.2 1.6 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DC_STAMP PF07782.13 KFP12946.1 - 0.037 13.8 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein ADP_ribosyl_GH PF03747.14 KFP12947.1 - 2e-55 188.6 1.4 2.3e-55 188.4 1.4 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase V-set PF07686.17 KFP12948.1 - 6.9e-62 206.4 4.9 2.1e-10 40.7 0.0 8.6 8 1 0 8 8 8 8 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12948.1 - 1.3e-50 169.9 7.5 6.3e-07 29.9 0.1 10.0 9 1 0 9 9 9 8 Immunoglobulin domain I-set PF07679.16 KFP12948.1 - 1.2e-36 124.6 4.3 8.2e-05 22.6 0.0 10.3 8 3 0 8 8 8 7 Immunoglobulin I-set domain ig PF00047.25 KFP12948.1 - 6.6e-29 99.9 9.9 0.00055 20.0 0.0 10.0 9 3 0 9 9 9 7 Immunoglobulin domain Ig_2 PF13895.6 KFP12948.1 - 3.6e-18 65.7 22.6 0.053 13.9 0.1 13.4 9 6 0 10 10 10 4 Immunoglobulin domain Ig_6 PF18452.1 KFP12948.1 - 4.3e-07 29.4 0.0 4.4 7.0 0.0 6.1 6 0 0 6 6 6 1 Immunoglobulin domain DUF3821 PF12863.7 KFP12948.1 - 0.0045 16.9 0.1 1.4 8.7 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3821) C2-set PF05790.15 KFP12948.1 - 0.0049 17.0 0.3 8.3 6.7 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Herpes_gI PF01688.17 KFP12948.1 - 0.071 13.0 0.0 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I V-set PF07686.17 KFP12949.1 - 4e-67 223.3 8.1 5.8e-13 49.0 0.0 7.2 7 0 0 7 7 7 7 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12949.1 - 1.3e-50 169.9 6.5 1.6e-06 28.6 0.0 8.2 7 2 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFP12949.1 - 1.5e-35 121.1 2.8 0.00016 21.6 0.0 10.0 7 5 0 7 7 7 7 Immunoglobulin I-set domain ig PF00047.25 KFP12949.1 - 4.4e-30 103.7 5.3 2.2e-05 24.5 0.0 9.1 8 4 0 8 8 8 6 Immunoglobulin domain Ig_2 PF13895.6 KFP12949.1 - 1.1e-23 83.3 11.2 0.011 16.0 0.0 11.5 8 6 0 8 8 8 6 Immunoglobulin domain Izumo-Ig PF16706.5 KFP12949.1 - 3e-10 40.0 1.1 0.032 14.3 0.0 6.8 7 0 0 7 7 7 3 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP12949.1 - 2.1e-06 27.2 0.0 3.2 7.4 0.0 5.5 6 0 0 6 6 6 1 Immunoglobulin domain Ig_4 PF16680.5 KFP12949.1 - 7.3e-05 23.0 0.2 8 6.8 0.0 6.5 7 0 0 7 7 7 1 T-cell surface glycoprotein CD3 delta chain Big_2 PF02368.18 KFP12949.1 - 0.064 13.2 1.5 0.61 10.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) V-set PF07686.17 KFP12950.1 - 1.7e-31 108.6 10.8 5.8e-08 32.9 0.1 5.8 5 0 0 5 5 5 5 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP12950.1 - 7.2e-30 103.4 8.0 1.8e-06 28.4 0.0 6.9 6 2 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KFP12950.1 - 8.6e-21 73.8 2.4 9.5e-05 22.4 0.0 7.6 7 2 1 8 8 8 5 Immunoglobulin I-set domain ig PF00047.25 KFP12950.1 - 2.8e-18 65.9 12.5 0.00041 20.5 0.0 7.8 7 4 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 KFP12950.1 - 1.3e-14 54.2 11.5 0.009 16.3 0.1 8.8 6 4 0 6 6 6 4 Immunoglobulin domain Izumo-Ig PF16706.5 KFP12950.1 - 5.9e-05 23.1 0.1 1.7 8.7 0.0 5.1 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP12950.1 - 0.00081 18.9 0.7 5.5 6.6 0.0 4.5 5 0 0 5 5 5 1 Immunoglobulin domain Ig_5 PF16681.5 KFP12950.1 - 0.016 15.6 0.4 10 6.6 0.0 4.7 5 1 0 5 5 5 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain adh_short PF00106.25 KFP12951.1 - 4.7e-34 117.6 0.3 7.6e-34 116.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP12951.1 - 1e-27 97.2 0.5 1.4e-27 96.7 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP12951.1 - 0.0002 21.3 0.2 0.00029 20.8 0.2 1.2 1 0 0 1 1 1 1 KR domain RRM_5 PF13893.6 KFP12952.1 - 9.8e-56 186.7 0.6 3.8e-42 142.8 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFP12952.1 - 5.2e-31 106.3 0.6 1.9e-09 37.2 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFP12952.1 - 1.6e-12 47.5 0.0 7e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFP12952.1 - 2.6e-08 33.6 0.1 1.2 9.1 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif Cys_Met_Meta_PP PF01053.20 KFP12952.1 - 0.084 11.4 0.2 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_transf_21 PF13506.6 KFP12953.1 - 1.1e-59 200.8 0.0 1.5e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFP12953.1 - 5.7e-24 85.3 0.0 6.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFP12953.1 - 1e-12 48.4 5.1 1.3e-12 48.0 5.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFP12953.1 - 0.00037 20.3 0.0 0.00083 19.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 G-gamma PF00631.22 KFP12954.1 - 1e-09 38.2 0.0 1.1e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain L31 PF09784.9 KFP12955.1 - 0.058 13.8 2.4 0.17 12.3 2.4 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Gag_p30 PF02093.16 KFP12956.1 - 5.5e-28 97.9 0.0 6.7e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein DUF1743 PF08489.11 KFP12956.1 - 0.0014 18.7 0.0 0.02 14.9 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1743) Gag_p24 PF00607.20 KFP12956.1 - 0.077 12.8 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) ADH_N_2 PF16884.5 KFP12957.1 - 2.9e-36 123.6 0.0 5.4e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFP12957.1 - 6.4e-24 84.4 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP12957.1 - 6.6e-11 43.4 0.0 1.4e-10 42.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PetL PF05115.14 KFP12957.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Thioredoxin PF00085.20 KFP12958.1 - 6.4e-30 103.2 1.1 7e-30 103.1 1.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFP12958.1 - 1.2e-05 25.5 0.2 1.7e-05 25.0 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP12958.1 - 0.00013 22.4 0.5 0.00033 21.1 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP12958.1 - 0.00052 20.1 0.2 0.00087 19.4 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFP12958.1 - 0.0011 18.4 0.3 0.0012 18.3 0.3 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFP12958.1 - 0.002 18.1 0.3 0.0026 17.7 0.3 1.2 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 KFP12958.1 - 0.0034 17.2 0.1 0.0037 17.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 KFP12958.1 - 0.0055 16.9 0.8 0.0097 16.1 0.8 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 KFP12958.1 - 0.019 14.7 0.1 0.023 14.5 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin Pkinase_Tyr PF07714.17 KFP12959.1 - 6.8e-94 314.0 0.0 9.3e-94 313.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 KFP12959.1 - 1.9e-45 152.9 0.0 3.3e-20 72.0 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12959.1 - 4e-42 142.7 0.4 2.1e-16 60.3 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Pkinase PF00069.25 KFP12959.1 - 1.3e-39 136.2 0.0 2.5e-39 135.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.6 KFP12959.1 - 2.2e-27 95.2 0.1 1.2e-10 41.6 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Kringle PF00051.18 KFP12959.1 - 2.4e-25 88.7 6.0 5.8e-25 87.4 6.0 1.7 1 0 0 1 1 1 1 Kringle domain ig PF00047.25 KFP12959.1 - 1.9e-18 66.4 0.0 1.5e-08 34.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Fz PF01392.22 KFP12959.1 - 1.1e-15 58.2 4.4 2.7e-15 56.9 4.4 1.7 1 0 0 1 1 1 1 Fz domain C2-set_2 PF08205.12 KFP12959.1 - 2.9e-10 40.1 0.1 0.0071 16.4 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP12959.1 - 3.4e-09 36.8 2.5 0.026 14.7 0.0 4.8 4 2 1 5 5 4 3 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP12959.1 - 1.1e-05 24.8 0.0 0.22 11.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.16 KFP12959.1 - 0.00029 19.7 0.0 0.43 9.3 0.0 2.9 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E Ig_4 PF16680.5 KFP12959.1 - 0.0015 18.7 0.0 2.5 8.4 0.0 3.9 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 KFP12959.1 - 0.0026 17.5 0.1 0.94 9.3 0.0 2.9 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 CD34_antigen PF06365.12 KFP12959.1 - 0.01 15.4 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Izumo-Ig PF16706.5 KFP12959.1 - 0.011 15.7 0.1 0.58 10.2 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Haspin_kinase PF12330.8 KFP12959.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sterol-sensing PF12349.8 KFP12959.1 - 2.7 7.8 4.2 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation 7tm_1 PF00001.21 KFP12960.1 - 2.5e-39 135.2 23.3 3.2e-39 134.8 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP12960.1 - 1.7e-05 24.7 16.6 0.00032 20.5 16.6 2.1 1 1 0 1 1 1 1 Olfactory receptor Guanylate_cyc PF00211.20 KFP12961.1 - 3.7e-65 219.0 0.3 2.9e-64 216.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KFP12961.1 - 2.3e-42 145.1 0.0 3.5e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12961.1 - 6.2e-34 117.6 0.0 1.1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFP12961.1 - 1.3e-06 28.0 1.5 2.1e-06 27.4 1.5 1.3 1 0 0 1 1 1 1 Heme NO binding associated TMEM215 PF15746.5 KFP12962.1 - 2.9e-121 403.0 0.8 3.2e-121 402.9 0.8 1.0 1 0 0 1 1 1 1 TMEM215 family zf-C3HC4_2 PF13923.6 KFP12963.1 - 1.3e-10 40.9 7.9 1.3e-10 40.9 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP12963.1 - 1.3e-09 37.8 5.5 1.3e-09 37.8 5.5 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP12963.1 - 3.8e-09 36.3 7.1 3.8e-09 36.3 7.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP12963.1 - 1e-08 35.4 9.0 1e-08 35.4 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP12963.1 - 3e-07 30.3 1.8 3e-07 30.3 1.8 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP12963.1 - 2.1e-05 24.4 8.2 2.1e-05 24.4 8.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP12963.1 - 3.3e-05 24.0 7.7 3.3e-05 24.0 7.7 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFP12963.1 - 5.5e-05 23.4 5.5 5.5e-05 23.4 5.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP12963.1 - 0.0013 18.5 9.9 0.02 14.7 9.5 2.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP12963.1 - 0.0043 17.1 3.1 0.013 15.5 3.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFP12963.1 - 3 7.7 14.7 0.5 10.2 9.4 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KFP12964.1 - 3.3e-67 222.3 0.1 2e-21 75.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP12964.1 - 8.3e-12 44.8 0.0 0.00013 21.6 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP12964.1 - 0.0001 22.5 0.0 0.49 10.6 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 KFP12964.1 - 0.00032 20.5 0.0 0.97 9.3 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP12964.1 - 0.00048 20.1 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 KFP12964.1 - 0.00051 20.1 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_2 PF04059.12 KFP12964.1 - 0.039 14.2 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 RNA_bind PF08675.11 KFP12964.1 - 0.099 12.7 0.0 2.6 8.1 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain CAAP1 PF15335.6 KFP12965.1 - 7e-29 100.2 9.4 1.1e-28 99.5 9.4 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 Rb_C PF08934.10 KFP12965.1 - 0.12 12.2 0.7 0.18 11.6 0.7 1.3 1 0 0 1 1 1 0 Rb C-terminal domain PUL PF08324.11 KFP12966.1 - 1.7e-65 221.0 5.6 2.3e-65 220.6 5.6 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KFP12966.1 - 5e-40 136.3 0.2 9.3e-40 135.4 0.2 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFP12966.1 - 9.9e-36 121.2 8.8 7.4e-06 26.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40_like PF17005.5 KFP12966.1 - 0.00014 21.3 0.0 0.12 11.7 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 KFP12966.1 - 0.0017 18.4 0.0 2 8.5 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ComR_TPR PF18710.1 KFP12966.1 - 0.13 11.8 1.6 1.6 8.2 0.8 2.1 2 0 0 2 2 2 0 ComR tetratricopeptide OmpH PF03938.14 KFP12967.1 - 0.0048 17.2 10.0 0.0048 17.2 10.0 5.8 1 1 3 4 4 4 2 Outer membrane protein (OmpH-like) Pkinase_Tyr PF07714.17 KFP12968.1 - 4.7e-92 307.9 0.0 6.9e-92 307.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP12968.1 - 2.9e-44 151.4 0.0 4.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_Tie2_1 PF10430.9 KFP12968.1 - 5.8e-40 135.6 0.2 1.5e-39 134.3 0.2 1.7 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 fn3 PF00041.21 KFP12968.1 - 2.8e-25 88.5 4.4 2e-11 44.1 0.7 4.3 3 1 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP12968.1 - 2.3e-09 37.7 1.0 0.0029 18.1 0.2 4.5 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain I-set PF07679.16 KFP12968.1 - 5.4e-07 29.6 0.0 0.00089 19.3 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12968.1 - 6.1e-07 30.0 0.1 0.054 14.1 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin domain EGF_2 PF07974.13 KFP12968.1 - 4e-06 27.1 58.9 9.1e-05 22.7 13.2 5.0 4 1 1 5 5 5 2 EGF-like domain fn3_2 PF16893.5 KFP12968.1 - 3.8e-05 23.8 0.2 0.016 15.3 0.1 3.6 3 0 0 3 3 3 1 Fibronectin type III domain ig PF00047.25 KFP12968.1 - 0.00076 19.6 0.0 0.03 14.5 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain APH PF01636.23 KFP12968.1 - 0.0016 18.4 0.0 0.14 12.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family hEGF PF12661.7 KFP12968.1 - 0.0024 18.4 7.3 0.0024 18.4 7.3 4.7 4 0 0 4 4 3 2 Human growth factor-like EGF Interfer-bind PF09294.10 KFP12968.1 - 0.0045 17.3 0.1 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Laminin_EGF PF00053.24 KFP12968.1 - 0.0063 16.6 48.6 1.5 9.0 17.4 4.3 2 1 2 4 4 4 2 Laminin EGF domain V-set PF07686.17 KFP12968.1 - 0.0094 16.1 0.0 0.68 10.1 0.0 3.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP12968.1 - 0.028 14.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Haspin_kinase PF12330.8 KFP12968.1 - 0.04 12.8 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_36C PF16874.5 KFP12968.1 - 0.047 14.2 0.0 1.1 9.8 0.0 3.0 3 0 0 3 3 2 0 Glycosyl hydrolase family 36 C-terminal domain DUF4702 PF15774.5 KFP12968.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Pkinase_fungal PF17667.1 KFP12968.1 - 0.16 10.7 0.4 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase EGF PF00008.27 KFP12968.1 - 5.5 7.4 50.6 0.13 12.6 12.9 4.6 4 0 0 4 4 4 0 EGF-like domain RVT_1 PF00078.27 KFP12969.1 - 0.0022 17.6 0.0 0.004 16.7 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mob1_phocein PF03637.17 KFP12970.1 - 1.7e-81 272.2 0.2 2e-81 272.0 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family C9orf72-like PF15019.6 KFP12971.1 - 2.2e-97 325.5 0.0 3.2e-97 324.9 0.0 1.3 1 0 0 1 1 1 1 C9orf72-like protein family LRR_8 PF13855.6 KFP12972.1 - 1.6e-59 197.5 57.7 6.9e-14 51.4 0.7 6.3 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP12972.1 - 2.8e-26 92.0 0.0 1.6e-10 41.1 0.0 3.2 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP12972.1 - 3.1e-21 75.1 31.9 0.0001 22.6 1.2 7.5 3 2 7 10 10 10 8 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP12972.1 - 2.2e-17 62.9 0.0 3.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP12972.1 - 1.6e-14 54.2 0.0 4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP12972.1 - 1.2e-09 38.2 0.0 2.8e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP12972.1 - 1.6e-09 37.0 23.5 2.9 8.8 0.0 11.7 11 1 0 11 11 11 1 Leucine Rich Repeat Ig_2 PF13895.6 KFP12972.1 - 1.7e-06 28.3 1.0 2.1e-06 28.0 0.0 1.7 2 0 0 2 2 1 1 Immunoglobulin domain LRRNT PF01462.18 KFP12972.1 - 2.8e-05 23.6 2.6 2.8e-05 23.6 2.6 3.2 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP12972.1 - 3.9e-05 23.2 13.9 0.025 14.1 4.3 3.3 2 1 1 3 3 3 3 Leucine-rich repeat V-set PF07686.17 KFP12972.1 - 0.00096 19.3 0.6 0.016 15.3 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFP12972.1 - 0.014 15.4 0.0 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 C17orf99 Ig domain LRRCT PF01463.24 KFP12972.1 - 0.064 13.8 0.1 6.9 7.5 0.0 3.2 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain Ig_6 PF18452.1 KFP12972.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFP12972.1 - 0.078 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain HTH_Tnp_IS630 PF01710.16 KFP12972.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase RVT_1 PF00078.27 KFP12973.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP12975.1 - 0.048 13.2 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Tetraspanin PF00335.20 KFP12976.1 - 5.7e-24 85.1 4.8 6.4e-24 84.9 4.8 1.0 1 0 0 1 1 1 1 Tetraspanin family YfhO PF09586.10 KFP12976.1 - 0.11 10.7 2.1 0.15 10.2 2.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1899 PF08953.11 KFP12977.1 - 1.9e-29 101.3 0.1 3.8e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KFP12977.1 - 2.5e-20 72.1 0.0 4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KFP12977.1 - 7.3e-18 64.6 4.8 8.5e-06 26.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP12977.1 - 4.6e-10 39.6 0.0 9.6e-06 25.8 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Calpain_III PF01067.22 KFP12977.1 - 0.054 13.7 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Calpain large subunit, domain III SGL PF08450.12 KFP12977.1 - 0.055 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 KFP12977.1 - 0.085 11.8 0.1 1.3 7.9 0.1 2.3 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sacchrp_dh_NADP PF03435.18 KFP12977.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DnaJ_C PF01556.18 KFP12978.1 - 2.7e-44 150.8 0.4 3.7e-44 150.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP12978.1 - 5.9e-27 93.6 2.3 1.1e-26 92.8 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFP12978.1 - 5.8e-15 55.4 20.7 1e-14 54.6 20.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFP12978.1 - 0.044 13.8 11.8 0.52 10.3 4.5 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFP12978.1 - 0.075 13.1 7.7 0.84 9.7 0.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WD40 PF00400.32 KFP12979.1 - 1.2e-40 136.7 8.9 7.6e-08 32.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP12979.1 - 5.5e-18 65.1 0.2 1.2e-05 25.5 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFP12979.1 - 1.2e-13 50.4 0.2 2.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 KFP12979.1 - 1.3e-13 50.6 0.6 0.0025 16.8 0.1 3.6 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP12979.1 - 4.2e-09 35.6 0.3 0.00087 18.1 0.1 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KFP12979.1 - 0.0015 18.4 1.3 1.2 8.9 0.2 3.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KFP12979.1 - 0.0033 17.2 1.7 1.6 8.4 0.0 4.4 5 0 0 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.12 KFP12979.1 - 0.018 14.9 0.0 0.7 9.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LisH PF08513.11 KFP12979.1 - 0.022 14.7 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 LisH Glyco_transf_7C PF02709.14 KFP12980.1 - 2.7e-32 110.2 0.3 5e-32 109.4 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KFP12980.1 - 1.1e-20 73.6 0.6 1.7e-20 73.0 0.6 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KFP12980.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Mito_carr PF00153.27 KFP12981.1 - 1.2e-50 169.4 7.2 3e-16 59.1 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Nnf1 PF03980.14 KFP12982.1 - 3.1e-23 82.2 1.5 4.6e-23 81.7 1.5 1.3 1 0 0 1 1 1 1 Nnf1 DNA_pol3_tau_4 PF12168.8 KFP12982.1 - 0.072 13.6 0.9 2.5 8.7 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Tuberin PF03542.16 KFP12982.1 - 0.082 12.0 0.0 0.19 10.8 0.0 1.6 1 1 0 1 1 1 0 Tuberin Peptidase_M3_N PF08439.10 KFP12982.1 - 0.34 11.2 3.8 0.25 11.6 0.8 2.2 2 0 0 2 2 2 0 Oligopeptidase F EST1 PF10374.9 KFP12983.1 - 7.9e-25 88.1 1.3 7.9e-25 88.1 1.3 2.3 3 0 0 3 3 3 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KFP12983.1 - 3.8e-21 75.8 0.8 5e-21 75.4 0.8 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Cpn60_TCP1 PF00118.24 KFP12984.1 - 9e-73 245.6 1.7 1e-72 245.4 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAP_beta PF05753.14 KFP12985.1 - 1.8e-50 170.8 0.0 2.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Tropomyosin PF00261.20 KFP12986.1 - 1.8e-103 345.1 88.5 3e-98 327.9 61.9 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP12986.1 - 5e-38 130.5 76.4 7.8e-34 116.9 44.4 3.1 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFP12986.1 - 1.4e-08 34.9 34.3 1e-05 25.6 7.2 3.8 1 1 3 4 4 4 3 Laminin Domain II CLZ PF16526.5 KFP12986.1 - 2.4e-07 31.0 51.7 3.8e-06 27.2 12.4 5.0 2 2 2 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ERM PF00769.19 KFP12986.1 - 0.00064 19.6 77.0 0.15 11.9 47.3 2.4 1 1 1 2 2 2 2 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 KFP12986.1 - 0.00087 19.2 9.3 0.00087 19.2 9.3 6.1 2 2 4 6 6 6 2 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 KFP12986.1 - 0.002 18.3 3.4 0.002 18.3 3.4 6.6 1 1 4 6 6 6 2 Haemolysin XhlA DUF745 PF05335.13 KFP12986.1 - 0.0067 16.2 51.0 0.17 11.6 9.6 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 KFP12986.1 - 0.0082 16.2 30.3 0.0082 16.2 30.3 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KFP12986.1 - 0.012 15.9 64.1 0.012 15.8 23.7 3.3 1 1 2 3 3 2 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 KFP12986.1 - 0.014 15.8 55.9 0.016 15.6 17.9 4.6 1 1 4 5 5 5 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 KFP12986.1 - 0.016 15.3 16.4 0.016 15.3 16.4 4.3 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KFP12986.1 - 0.027 15.1 0.6 0.027 15.1 0.6 5.3 1 1 5 6 6 6 0 SlyX DUF1664 PF07889.12 KFP12986.1 - 0.033 14.2 33.9 0.21 11.6 2.9 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFP12986.1 - 0.05 13.1 57.0 1.2 8.5 21.5 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 MscS_porin PF12795.7 KFP12986.1 - 0.063 12.8 53.6 0.99 8.9 8.6 3.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1794 PF08768.11 KFP12986.1 - 0.22 11.4 5.2 4.2 7.3 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1794) AAA_13 PF13166.6 KFP12986.1 - 0.26 9.9 50.8 0.45 9.1 13.3 2.1 1 1 1 2 2 2 0 AAA domain Laminin_I PF06008.14 KFP12986.1 - 0.29 10.8 58.1 0.58 9.8 20.5 3.3 1 1 2 3 3 3 0 Laminin Domain I Lebercilin PF15619.6 KFP12986.1 - 0.33 10.6 65.5 1.2 8.8 29.2 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 KFP12986.1 - 0.43 10.7 52.3 1.6 8.8 14.2 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 KFP12986.1 - 0.61 8.4 60.2 1.1 7.5 25.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF16 PF01519.16 KFP12986.1 - 0.72 10.4 40.8 0.37 11.3 0.4 4.5 1 1 3 4 4 4 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KFP12986.1 - 0.94 10.0 16.0 2.7 8.5 0.7 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KFP12986.1 - 0.97 9.6 33.0 0.24 11.6 7.3 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KFP12986.1 - 1.3 8.5 38.0 7.7 6.0 13.4 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit EzrA PF06160.12 KFP12986.1 - 1.4 7.0 58.3 0.28 9.3 7.6 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 KFP12986.1 - 2 8.4 16.7 9.4 6.3 3.7 3.8 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 KFP12986.1 - 2.9 6.3 22.8 2.7 6.4 1.2 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family TTKRSYEDQ PF10212.9 KFP12986.1 - 4.8 6.0 39.1 1.1 8.2 15.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3450 PF11932.8 KFP12986.1 - 5 6.4 52.6 0.013 14.8 10.2 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) GAS PF13851.6 KFP12986.1 - 5.2 6.4 66.8 0.63 9.4 16.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 KFP12986.1 - 6.6 4.8 62.7 0.89 7.7 20.5 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Fmp27_WPPW PF10359.9 KFP12986.1 - 6.7 5.4 40.0 0.26 10.1 10.2 2.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain BST2 PF16716.5 KFP12986.1 - 7 7.3 50.2 0.11 13.1 8.8 4.9 1 1 6 7 7 7 0 Bone marrow stromal antigen 2 HOOK PF05622.12 KFP12986.1 - 7.2 4.6 60.5 0.013 13.7 16.1 2.2 1 1 1 2 2 2 0 HOOK protein SNARE PF05739.19 KFP12986.1 - 7.7 6.6 15.8 2.3 8.3 0.1 5.1 5 0 0 5 5 5 0 SNARE domain T3SSipB PF16535.5 KFP12986.1 - 9 6.8 49.9 6.5 7.2 7.4 4.6 1 1 3 4 4 4 0 Type III cell invasion protein SipB LSM PF01423.22 KFP12990.1 - 8.4e-21 73.4 0.6 9.2e-21 73.3 0.6 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFP12990.1 - 0.078 13.1 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KFP12990.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain Avl9 PF09794.9 KFP12991.1 - 5.2e-135 450.0 0.0 6.4e-135 449.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KFP12991.1 - 7.8e-10 38.8 3.0 1.9e-06 27.7 2.5 3.3 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KFP12991.1 - 9.1e-07 28.8 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 KFP12991.1 - 0.11 13.0 0.5 0.41 11.1 0.0 2.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 KFP12991.1 - 0.24 11.3 2.4 1.5 8.7 0.1 2.5 3 0 0 3 3 3 0 DENN (AEX-3) domain BACK PF07707.15 KFP12992.1 - 1.4e-20 73.3 1.5 2.6e-20 72.5 1.5 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP12992.1 - 1.3e-18 66.5 1.9 0.00011 22.4 0.0 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KFP12992.1 - 5.4e-18 64.3 23.5 1.4e-09 37.4 0.1 7.3 5 3 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KFP12992.1 - 5.7e-09 35.6 4.8 0.037 14.0 0.0 5.1 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFP12992.1 - 4.6e-06 26.5 11.2 0.05 13.6 0.0 5.3 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP12992.1 - 4.8e-05 23.5 4.9 0.25 11.7 0.1 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain baeRF_family5 PF18846.1 KFP12992.1 - 0.11 12.7 0.3 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 5 Kelch_5 PF13854.6 KFP12992.1 - 0.14 12.2 4.2 7.1 6.7 0.1 3.8 4 0 0 4 4 4 0 Kelch motif WYL_2 PF10902.8 KFP12992.1 - 0.24 11.8 2.7 23 5.4 0.0 3.6 4 0 0 4 4 4 0 WYL_2, Sm-like SH3 beta-barrel fold CENP-B_dimeris PF09026.10 KFP12993.1 - 0.02 15.3 3.2 0.063 13.7 3.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3727 PF12527.8 KFP12993.1 - 0.55 10.5 3.3 1.6 9.0 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) zf-CCHC_6 PF15288.6 KFP12994.1 - 0.0098 15.7 0.7 0.021 14.7 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle FKBP_C PF00254.28 KFP12996.1 - 1.6e-102 336.0 0.0 1.2e-26 92.8 0.0 5.1 5 0 0 5 5 5 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KFP12996.1 - 1.2e-09 37.0 0.9 0.00049 19.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP12996.1 - 2.1e-06 28.1 1.0 1.9e-05 25.0 1.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP12996.1 - 9.2e-06 24.9 0.5 0.082 12.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP12996.1 - 1.2e-05 24.8 0.5 0.083 12.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP12996.1 - 9.8e-05 22.1 0.1 0.37 10.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair DUF2895 PF11444.8 KFP12996.1 - 0.0083 15.5 0.0 3.2 7.1 0.0 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2895) DUF1702 PF08012.11 KFP12996.1 - 0.12 11.2 0.1 7.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1702) UMPH-1 PF05822.12 KFP12997.1 - 3.8e-121 403.2 5.9 4.4e-121 403.0 5.9 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFP12997.1 - 0.00015 22.2 0.1 0.00031 21.2 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_7 PF13840.6 KFP12997.1 - 0.0013 18.5 0.4 5.1 7.0 0.1 3.3 3 0 0 3 3 3 2 ACT domain CIDE-N PF02017.15 KFP12997.1 - 0.012 15.7 0.1 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 CIDE-N domain NIF PF03031.18 KFP12997.1 - 0.022 14.5 0.2 1.4 8.7 0.0 2.7 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase PHTB1_N PF14727.6 KFP12999.1 - 1.5e-167 558.2 0.0 1.9e-167 557.8 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KFP12999.1 - 1.5e-155 517.9 3.4 2e-155 517.5 3.4 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus VWD PF00094.25 KFP13000.1 - 1.1e-36 126.5 0.1 2.2e-36 125.5 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.18 KFP13000.1 - 3e-23 81.9 147.6 8.8e-10 38.8 14.8 7.9 6 1 0 6 6 6 5 von Willebrand factor type C domain C8 PF08742.11 KFP13000.1 - 5.7e-15 55.5 14.8 5.7e-15 55.5 14.8 5.0 5 1 1 6 6 6 1 C8 domain TIL PF01826.17 KFP13000.1 - 1.5e-10 41.2 14.3 1.5e-10 41.2 14.3 9.2 4 2 2 6 6 6 1 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFP13000.1 - 0.0039 17.1 12.4 0.0039 17.1 12.4 9.0 6 3 3 9 9 9 4 TILa domain PilI PF10623.9 KFP13000.1 - 2.1 8.5 8.4 4.2 7.6 0.1 3.5 3 0 0 3 3 3 0 Plasmid conjugative transfer protein PilI 7tm_1 PF00001.21 KFP13001.1 - 7.8e-44 150.0 14.2 1e-43 149.6 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP13001.1 - 0.043 13.5 13.7 0.32 10.7 13.7 2.1 1 1 0 1 1 1 0 Olfactory receptor PH PF00169.29 KFP13002.1 - 2.1e-19 70.0 0.6 1.2e-16 61.1 0.3 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP13002.1 - 0.003 18.0 8.4 0.011 16.1 3.1 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain OmpH PF03938.14 KFP13002.1 - 0.0058 17.0 11.9 0.0058 17.0 11.9 4.7 3 1 0 4 4 4 2 Outer membrane protein (OmpH-like) Folliculin_C PF16692.5 KFP13003.1 - 4.8e-91 304.5 0.1 8.3e-91 303.7 0.1 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 KFP13003.1 - 1.3e-51 175.1 0.0 2.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF5357 PF17310.2 KFP13003.1 - 0.03 12.9 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) PCI PF01399.27 KFP13004.1 - 1.3e-19 70.7 1.0 5.2e-19 68.7 0.2 2.3 2 0 0 2 2 2 1 PCI domain RasGEF PF00617.19 KFP13004.1 - 0.0054 17.0 1.0 0.49 10.6 0.1 2.9 3 0 0 3 3 3 1 RasGEF domain TPR_1 PF00515.28 KFP13004.1 - 0.0078 16.0 2.5 0.017 15.0 0.9 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP13004.1 - 0.046 13.9 2.1 1.4 9.3 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.15 KFP13004.1 - 0.051 13.7 0.2 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Sel1 PF08238.12 KFP13004.1 - 0.067 13.9 1.0 0.18 12.6 1.0 1.8 1 0 0 1 1 1 0 Sel1 repeat TPR_10 PF13374.6 KFP13004.1 - 0.068 13.1 0.3 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP13004.1 - 0.074 13.2 2.3 0.16 12.1 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP13004.1 - 0.11 12.8 0.1 2.5 8.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NT5C PF06941.12 KFP13005.1 - 2.7e-26 92.6 0.0 3.1e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Med9 PF07544.13 KFP13006.1 - 9.3e-20 70.5 4.0 1e-19 70.4 4.0 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KFP13006.1 - 1.5e-08 35.0 2.4 1.8e-08 34.8 2.4 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex APG17 PF04108.12 KFP13006.1 - 0.0025 17.0 0.3 0.0027 16.9 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 PHA_synth_III_E PF09712.10 KFP13006.1 - 0.0028 16.8 0.6 0.003 16.7 0.6 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) HSBP1 PF06825.12 KFP13006.1 - 0.015 15.2 0.7 0.015 15.2 0.7 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DASH_Duo1 PF08651.10 KFP13006.1 - 0.016 15.0 0.3 0.024 14.4 0.3 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 4HB_MCP_1 PF12729.7 KFP13006.1 - 0.02 14.5 0.2 0.022 14.3 0.2 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ELK PF03789.13 KFP13006.1 - 0.027 14.6 1.8 0.13 12.4 0.5 2.3 2 0 0 2 2 2 0 ELK domain GrpE PF01025.19 KFP13006.1 - 0.039 13.6 0.6 0.041 13.5 0.6 1.1 1 0 0 1 1 1 0 GrpE FapA PF03961.13 KFP13006.1 - 0.054 12.1 2.3 0.062 11.9 2.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A XPC-binding PF09280.11 KFP13006.1 - 0.076 12.8 7.1 4.5 7.1 3.9 2.5 2 1 0 2 2 2 0 XPC-binding domain DUF3452 PF11934.8 KFP13006.1 - 0.078 12.5 0.8 0.11 12.1 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Enkurin PF13864.6 KFP13006.1 - 0.16 12.5 5.3 0.53 10.8 0.6 2.0 1 1 1 2 2 2 0 Calmodulin-binding DUF2232 PF09991.9 KFP13006.1 - 0.17 11.0 1.0 0.2 10.8 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ras PF00071.22 KFP13007.1 - 3.8e-37 127.4 0.0 5.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13007.1 - 7.3e-13 48.8 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP13007.1 - 4e-07 29.6 0.0 7.7e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP13007.1 - 0.00032 20.3 0.0 0.0022 17.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP13007.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP13007.1 - 0.046 13.1 0.0 0.16 11.3 0.0 1.9 2 1 0 2 2 2 0 Bacterial TniB protein GAPT PF11770.8 KFP13007.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MMR_HSR1 PF01926.23 KFP13007.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PEMT PF04191.13 KFP13008.1 - 1.6e-20 73.5 3.9 1.6e-20 73.5 3.9 1.9 2 1 0 2 2 2 1 Phospholipid methyltransferase Herpes_UL74 PF07982.12 KFP13008.1 - 0.061 12.3 0.1 0.082 11.8 0.1 1.1 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Nup_retrotrp_bd PF10599.9 KFP13009.1 - 0.38 11.4 4.3 0.54 11.0 1.9 2.5 2 0 0 2 2 2 0 Retro-transposon transporting motif SPARC_Ca_bdg PF10591.9 KFP13010.1 - 3.4e-34 117.5 2.0 6e-34 116.8 2.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFP13010.1 - 4.8e-18 64.6 6.7 4.8e-18 64.6 6.7 3.2 3 1 0 3 3 3 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFP13010.1 - 2.7e-13 49.8 16.4 1.8e-12 47.1 10.6 3.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP13010.1 - 5.5e-06 26.3 7.6 5.5e-06 26.3 7.6 3.6 3 1 0 3 3 3 1 Kazal-type serine protease inhibitor domain TFIIA PF03153.13 KFP13010.1 - 4.5 7.2 10.0 5.9 6.8 10.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Annexin PF00191.20 KFP13011.1 - 6.1e-82 269.7 8.7 1.8e-21 75.9 0.2 4.0 4 0 0 4 4 4 4 Annexin PIN_2 PF10130.9 KFP13012.1 - 0.037 14.3 0.3 0.081 13.2 0.2 1.6 1 1 0 1 1 1 0 PIN domain zf-B_box PF00643.24 KFP13012.1 - 1.8 8.8 5.9 0.22 11.7 0.8 2.0 2 0 0 2 2 2 0 B-box zinc finger DEAD PF00270.29 KFP13013.1 - 3.3e-18 66.0 0.1 1.5e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFP13013.1 - 1.8e-14 54.1 2.3 1.2e-11 44.9 0.0 4.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP13013.1 - 2e-06 28.1 0.0 1.1e-05 25.8 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TAtT PF16811.5 KFP13013.1 - 0.019 14.3 0.6 0.055 12.8 0.6 1.7 1 0 0 1 1 1 0 TRAP transporter T-component SpvD PF05563.12 KFP13013.1 - 0.02 14.5 0.3 0.058 13.0 0.3 1.8 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD Ribosomal_L18p PF00861.22 KFP13013.1 - 0.053 13.9 0.7 0.18 12.2 0.7 1.9 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast BNIP2 PF12496.8 KFP13013.1 - 0.14 12.6 0.3 0.48 10.9 0.3 1.9 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Bacillus_HBL PF05791.11 KFP13013.1 - 2.3 8.0 7.1 3.3 7.5 0.0 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ThiD2 PF17792.1 KFP13013.1 - 8 6.9 7.8 1.3 9.5 2.2 2.5 3 0 0 3 3 3 0 ThiD2 family I-set PF07679.16 KFP13014.1 - 3.5e-103 337.9 0.0 6.1e-22 77.5 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13014.1 - 3.8e-69 229.3 0.0 2.1e-15 57.1 0.0 6.9 6 1 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 KFP13014.1 - 1.9e-49 165.9 0.1 6.5e-10 39.2 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP13014.1 - 3.9e-49 164.8 0.2 9.2e-10 38.6 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFP13014.1 - 2.2e-18 66.4 5.8 0.056 13.6 0.0 8.6 5 4 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP13014.1 - 7.2e-15 54.8 0.2 0.027 14.5 0.0 6.5 5 1 0 5 5 5 5 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP13014.1 - 1.8e-05 25.1 0.0 1.4 9.3 0.0 4.6 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFP13014.1 - 2.9e-05 24.0 0.0 1.3 9.1 0.0 5.1 5 0 0 5 5 5 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFP13014.1 - 4.9e-05 23.5 0.0 0.23 11.7 0.0 4.4 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFP13014.1 - 0.0003 20.3 0.1 0.2 11.3 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain adh_short_C2 PF13561.6 KFP13015.1 - 3.6e-61 206.7 0.9 4.4e-61 206.4 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP13015.1 - 1.1e-55 188.1 2.9 1.3e-55 187.9 2.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP13015.1 - 2.7e-17 63.2 2.1 1.4e-16 61.0 1.5 1.9 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KFP13015.1 - 0.0021 18.0 0.2 0.0027 17.6 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFP13015.1 - 0.011 16.0 0.4 0.033 14.4 0.1 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFP13015.1 - 0.014 14.8 0.1 0.035 13.5 0.2 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFP13015.1 - 0.044 13.8 0.4 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SH3_9 PF14604.6 KFP13017.1 - 4.9e-54 180.0 1.3 5.1e-15 55.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 KFP13017.1 - 3.9e-50 167.2 1.8 3.7e-12 45.7 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 KFP13017.1 - 1.9e-35 120.3 1.8 5.3e-09 35.6 0.1 4.3 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4 PF00097.25 KFP13017.1 - 4.1e-09 36.2 7.0 7.9e-09 35.2 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP13017.1 - 5.6e-09 35.9 5.5 1.4e-08 34.7 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP13017.1 - 7.2e-09 35.4 7.4 1.6e-08 34.3 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP13017.1 - 1.8e-08 34.6 7.6 4e-08 33.5 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP13017.1 - 1.3e-06 28.2 6.6 2.4e-06 27.4 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP13017.1 - 1.9e-06 27.6 8.8 3.4e-06 26.8 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP13017.1 - 0.00011 22.3 7.6 0.00021 21.4 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP13017.1 - 0.00044 20.0 5.0 0.00044 20.0 5.0 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP13017.1 - 0.00076 19.3 8.2 0.0053 16.6 8.6 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KFP13017.1 - 0.007 16.1 2.8 0.02 14.6 2.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 KFP13017.1 - 0.12 12.2 2.4 0.3 11.0 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KFP13017.1 - 0.12 12.1 5.2 0.25 11.1 5.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 KFP13017.1 - 0.33 11.3 3.7 0.86 9.9 3.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Trm112p PF03966.16 KFP13017.1 - 1.7 9.3 5.9 5.3 7.7 5.9 1.9 1 0 0 1 1 1 0 Trm112p-like protein DZR PF12773.7 KFP13017.1 - 9.9 6.3 7.5 30 4.8 7.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon Voltage_CLC PF00654.20 KFP13018.1 - 1.5e-105 353.4 20.5 2.2e-105 352.8 20.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KFP13018.1 - 9.3e-14 51.6 0.8 7.1e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF2228 PF10228.9 KFP13019.1 - 2e-99 332.4 0.1 2.3e-99 332.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) RVT_1 PF00078.27 KFP13020.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP13020.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase LRR_8 PF13855.6 KFP13025.1 - 1.9e-38 130.0 35.8 2.2e-13 49.8 5.4 7.0 2 1 5 7 7 7 6 Leucine rich repeat LRR_5 PF13306.6 KFP13025.1 - 5.9e-21 74.8 0.2 7.9e-09 35.6 0.0 3.7 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP13025.1 - 2.2e-18 66.0 48.8 0.0023 18.3 4.4 7.8 5 2 1 8 8 7 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP13025.1 - 5.3e-13 48.9 0.0 1.9e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13025.1 - 2.2e-12 47.4 0.0 5.8e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFP13025.1 - 7.5e-10 38.6 25.3 7.7e-05 22.3 0.7 4.5 1 1 4 5 5 5 5 Leucine-rich repeat ig PF00047.25 KFP13025.1 - 3.1e-08 33.7 0.0 6.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP13025.1 - 2.4e-07 31.0 0.1 5e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Ig_2 PF13895.6 KFP13025.1 - 2.5e-06 27.7 0.0 6.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.24 KFP13025.1 - 0.002 18.5 0.1 0.0048 17.3 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain V-set PF07686.17 KFP13025.1 - 0.0031 17.7 0.2 0.38 11.0 0.2 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP13025.1 - 0.01 16.4 0.1 0.027 15.0 0.1 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain LRRNT PF01462.18 KFP13025.1 - 0.49 10.1 7.4 0.07 12.8 1.1 3.0 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain DHR-2 PF06920.13 KFP13027.1 - 1.6e-110 370.3 7.8 9.6e-110 367.7 7.8 2.1 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 KFP13027.1 - 8.5e-102 340.9 0.0 1.7e-101 339.9 0.0 1.6 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFP13027.1 - 1.3e-53 181.7 0.0 3e-52 177.3 0.0 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KFP13027.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP13027.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain zf-C2H2_2 PF12756.7 KFP13028.1 - 3.9e-43 145.9 25.2 1.2e-22 80.1 7.5 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFP13028.1 - 4.5e-10 39.5 21.6 0.0013 19.4 0.4 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP13028.1 - 8.2e-05 22.8 2.4 8.2e-05 22.8 2.4 4.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFP13028.1 - 0.00049 20.4 1.6 0.00049 20.4 1.6 5.5 5 2 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.15 KFP13028.1 - 0.0086 16.1 0.2 0.0086 16.1 0.2 5.0 5 0 0 5 5 5 2 BED zinc finger zf-C2H2_11 PF16622.5 KFP13028.1 - 0.038 13.8 12.6 0.61 9.9 0.4 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFP13028.1 - 0.078 13.4 1.3 0.078 13.4 1.3 3.9 4 1 0 4 4 4 0 Zinc-finger of C2H2 type YokU PF14122.6 KFP13028.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.0 5 0 0 5 5 5 0 YokU-like protein, putative antitoxin zf-DBF PF07535.12 KFP13028.1 - 0.22 11.7 8.8 1.1 9.4 0.5 2.9 2 0 0 2 2 2 0 DBF zinc finger IFRD PF05004.13 KFP13030.1 - 6.6e-111 370.3 6.0 7.9e-111 370.0 6.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KFP13030.1 - 3.3e-24 85.2 0.7 3.3e-24 85.2 0.7 2.1 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT PF02985.22 KFP13030.1 - 0.025 14.8 0.5 18 5.9 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat DUF4577 PF15145.6 KFP13031.1 - 3.1e-46 156.6 1.0 3.3e-46 156.5 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) MscL PF01741.18 KFP13031.1 - 0.0065 16.8 0.1 0.0069 16.7 0.1 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Tetraspanin PF00335.20 KFP13031.1 - 0.007 16.1 0.4 0.0097 15.6 0.4 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF948 PF06103.11 KFP13031.1 - 0.042 14.1 0.5 0.08 13.2 0.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COX7a PF02238.15 KFP13032.1 - 2 8.9 5.1 5.7 7.4 0.3 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII CrgA PF06781.12 KFP13032.1 - 9.8 6.3 13.9 0.83 9.7 4.0 3.3 2 1 0 2 2 2 0 Cell division protein CrgA Bmt2 PF11968.8 KFP13033.1 - 5.8e-08 32.8 0.3 3e-05 24.0 0.3 2.1 1 1 1 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF4730 PF15873.5 KFP13034.1 - 7.3e-21 74.2 4.4 8.7e-21 73.9 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) Sterol-sensing PF12349.8 KFP13034.1 - 0.026 14.4 0.1 0.026 14.4 0.1 1.0 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation RseC_MucC PF04246.12 KFP13034.1 - 0.085 12.8 0.7 0.089 12.7 0.7 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FixS PF03597.15 KFP13034.1 - 0.4 10.4 4.2 3.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Antimicrobial10 PF08105.11 KFP13034.1 - 1.9 8.7 4.6 0.85 9.7 1.2 1.9 1 1 1 2 2 2 0 Metchnikowin family TRAPP PF04051.16 KFP13035.1 - 3.2e-37 127.5 0.0 3.6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ADP_ribosyl_GH PF03747.14 KFP13036.1 - 6.9e-56 190.1 0.0 7.9e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CxC7 PF18866.1 KFP13036.1 - 0.42 10.8 1.5 0.94 9.7 0.2 2.2 2 1 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases Tektin PF03148.14 KFP13037.1 - 8.4e-134 446.1 43.1 9.5e-134 445.9 43.1 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.12 KFP13037.1 - 1.6e-05 25.0 15.1 0.12 12.4 1.4 4.5 3 2 1 4 4 4 3 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFP13037.1 - 0.039 14.2 8.6 0.81 10.0 0.3 4.2 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KFP13037.1 - 0.21 12.0 7.1 3.4 8.2 0.1 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KFP13037.1 - 0.4 11.0 24.8 0.64 10.3 7.2 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) COG5 PF10392.9 KFP13037.1 - 0.62 10.2 15.2 6.5 6.9 0.2 4.3 2 2 2 4 4 4 0 Golgi transport complex subunit 5 Pox_A_type_inc PF04508.12 KFP13037.1 - 0.68 9.9 6.2 0.5 10.3 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Bap31_Bap29_C PF18035.1 KFP13037.1 - 1.4 9.0 5.4 33 4.6 0.1 3.8 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1043 PF06295.12 KFP13037.1 - 2.6 8.1 15.7 2.3 8.2 0.3 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1043) LPP PF04728.13 KFP13037.1 - 4.7 7.7 13.7 9.3 6.7 0.0 4.7 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Prefoldin PF02996.17 KFP13037.1 - 6.4 6.7 16.2 7.5 6.5 0.2 4.4 4 0 0 4 4 4 0 Prefoldin subunit COG2 PF06148.11 KFP13037.1 - 8.3 6.5 20.0 2 8.5 2.3 4.4 2 2 4 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 Piwi PF02171.17 KFP13038.1 - 7.5e-114 380.0 0.0 1.1e-113 379.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFP13038.1 - 1e-32 112.2 0.4 3.5e-32 110.5 0.1 2.2 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 KFP13038.1 - 8e-29 100.2 0.8 1.3e-28 99.5 0.8 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFP13038.1 - 4.2e-26 92.2 0.0 1.2e-25 90.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFP13038.1 - 1.4e-22 79.1 0.0 3.2e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFP13038.1 - 3.4e-08 33.7 0.1 1.1e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain Piwi PF02171.17 KFP13039.1 - 2.9e-105 351.9 0.0 4.5e-105 351.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFP13039.1 - 4e-33 113.5 0.4 1.4e-32 111.8 0.1 2.2 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 KFP13039.1 - 3.5e-30 105.4 0.0 9e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFP13039.1 - 4.3e-28 97.8 1.9 7.4e-28 97.1 1.9 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 KFP13039.1 - 1.2e-22 79.3 0.1 2.8e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFP13039.1 - 3.4e-15 56.1 0.0 7.8e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Proteasome PF00227.26 KFP13041.1 - 6.3e-35 120.4 0.0 6.9e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Neurochondrin PF05536.11 KFP13042.1 - 1.1e-225 750.7 0.0 1.2e-225 750.5 0.0 1.0 1 0 0 1 1 1 1 Neurochondrin Y_Y_Y PF07495.13 KFP13043.1 - 4e-13 49.1 1.3 0.0024 17.8 0.1 5.0 5 0 0 5 5 5 3 Y_Y_Y domain PKD PF00801.20 KFP13043.1 - 4.1e-12 45.8 8.4 0.0068 16.2 0.1 5.0 4 0 0 4 4 4 4 PKD domain DUF4625 PF15418.6 KFP13043.1 - 5.1e-11 42.9 0.3 0.26 11.5 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) Big_9 PF17963.1 KFP13043.1 - 1e-10 42.2 33.7 0.00046 20.9 1.7 5.5 5 0 0 5 5 5 4 Bacterial Ig domain He_PIG PF05345.12 KFP13043.1 - 8.9e-06 25.8 7.2 0.34 11.1 0.0 5.2 6 0 0 6 6 5 2 Putative Ig domain DUF4998 PF16389.5 KFP13043.1 - 1.2e-05 25.0 1.6 0.5 9.9 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function PKD_2 PF16407.5 KFP13043.1 - 1.7e-05 25.1 1.6 0.5 10.5 0.0 4.2 2 1 2 4 4 4 1 PKD-like family DUF5013 PF16405.5 KFP13043.1 - 4.4e-05 23.8 0.9 0.097 12.9 0.1 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF5013) Wzt_C PF14524.6 KFP13043.1 - 0.001 19.1 0.0 11 6.0 0.0 4.1 4 0 0 4 4 4 1 Wzt C-terminal domain AMPK1_CBM PF16561.5 KFP13043.1 - 0.0016 18.6 0.3 12 6.2 0.0 5.1 6 0 0 6 6 6 0 Glycogen recognition site of AMP-activated protein kinase fn3 PF00041.21 KFP13043.1 - 0.003 17.9 0.4 0.26 11.7 0.0 3.6 3 0 0 3 3 3 1 Fibronectin type III domain Cadherin_5 PF17892.1 KFP13043.1 - 0.023 14.7 5.2 5.3 7.1 0.1 4.4 4 0 0 4 4 4 0 Cadherin-like domain DUF5011 PF16403.5 KFP13043.1 - 0.093 12.9 10.2 30 4.8 0.1 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF5011) TMEM154 PF15102.6 KFP13043.1 - 0.22 11.4 3.1 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family PAN_4 PF14295.6 KFP13043.1 - 1.9 8.4 10.8 11 6.1 5.6 2.5 2 0 0 2 2 2 0 PAN domain EGF_2 PF07974.13 KFP13043.1 - 3.1 8.2 13.3 0.058 13.8 4.8 2.4 2 0 0 2 2 2 0 EGF-like domain DUF3504 PF12012.8 KFP13044.1 - 4.1e-65 218.7 2.0 4.1e-65 218.7 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) zf-FCS PF06467.14 KFP13044.1 - 8.9e-53 176.0 101.3 6e-09 35.7 5.0 10.7 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 KFP13044.1 - 0.049 13.1 0.1 0.049 13.1 0.1 9.1 7 2 2 9 9 9 0 zinc-finger of the FCS-type, C2-C2 YHS PF04945.13 KFP13044.1 - 0.12 12.5 45.1 0.15 12.2 0.9 9.0 10 0 0 10 10 10 0 YHS domain RRM_1 PF00076.22 KFP13045.1 - 1.5e-30 104.8 0.1 7.3e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFP13045.1 - 5.6e-29 100.1 1.5 1.4e-28 98.8 1.5 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFP13045.1 - 0.0015 18.6 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif AAA_21 PF13304.6 KFP13045.1 - 0.08 12.7 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RVT_1 PF00078.27 KFP13046.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 KFP13047.1 - 2.6e-50 168.0 49.9 3.3e-12 46.0 5.2 7.0 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP13047.1 - 2.1e-15 56.8 0.0 6.9e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP13047.1 - 3.4e-14 52.7 45.0 0.011 16.2 2.6 9.1 3 2 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP13047.1 - 6.3e-07 29.1 16.0 0.0088 15.6 0.4 4.3 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP13047.1 - 3.7e-05 23.7 31.7 7.8 7.5 0.7 10.7 11 1 0 11 11 11 2 Leucine Rich Repeat LRRNT PF01462.18 KFP13047.1 - 0.47 10.2 16.3 0.036 13.7 3.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain MIF4G PF02854.19 KFP13048.1 - 7.5e-58 195.6 1.7 7.5e-58 195.6 1.7 2.2 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.18 KFP13048.1 - 1.2e-20 73.4 1.6 3.5e-20 71.9 1.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.17 KFP13048.1 - 4.1e-13 49.3 0.2 4.1e-13 49.3 0.2 3.1 3 0 0 3 3 3 1 MA3 domain TPR_19 PF14559.6 KFP13049.1 - 1.5e-37 127.9 13.9 2.8e-05 24.5 0.0 10.2 8 1 3 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFP13049.1 - 2.4e-37 125.2 40.0 8.4e-05 22.2 0.1 13.4 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP13049.1 - 8.4e-36 119.2 47.6 9.4e-05 22.2 0.0 15.5 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 KFP13049.1 - 1.8e-30 102.6 32.5 0.00041 20.3 0.0 13.4 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFP13049.1 - 3.2e-30 102.2 16.5 0.004 17.9 0.0 13.7 8 3 5 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFP13049.1 - 1.7e-27 95.8 19.2 8.2e-06 26.4 0.1 10.8 8 3 3 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP13049.1 - 3.9e-24 84.7 35.7 1.6e-06 28.3 0.3 10.6 7 4 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFP13049.1 - 9.1e-23 79.0 28.6 0.077 13.4 0.4 14.5 16 1 1 17 17 16 7 Tetratricopeptide repeat TPR_10 PF13374.6 KFP13049.1 - 2.9e-16 58.7 28.2 0.088 12.7 0.2 12.2 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFP13049.1 - 3e-15 55.8 33.2 0.0058 17.2 0.0 13.1 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP13049.1 - 5.5e-13 48.4 26.5 2.5e-05 23.9 0.0 11.5 11 3 2 13 13 13 3 TPR repeat TPR_7 PF13176.6 KFP13049.1 - 7.4e-13 47.6 31.3 0.024 14.7 0.1 11.9 13 0 0 13 13 12 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP13049.1 - 6.3e-08 32.7 30.8 0.036 14.3 0.2 7.1 5 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFP13049.1 - 2e-05 24.7 3.5 2.8 8.2 0.1 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KFP13049.1 - 0.00045 19.1 2.0 0.59 8.8 0.2 4.2 3 1 1 4 4 4 1 Protein kinase G tetratricopeptide repeat TPPII_N PF12583.8 KFP13049.1 - 0.039 14.5 12.5 0.2 12.2 0.2 4.8 5 0 0 5 5 4 0 Tripeptidyl peptidase II N terminal Rapsyn_N PF10579.9 KFP13049.1 - 0.64 10.2 11.4 2.6 8.2 0.0 5.0 5 1 0 5 5 4 0 Rapsyn N-terminal myristoylation and linker region DUF4810 PF16068.5 KFP13049.1 - 3 8.5 10.0 12 6.6 0.0 4.4 4 0 0 4 4 2 0 Domain of unknown function (DUF4810) Complex1_LYR_2 PF13233.6 KFP13049.1 - 6.9 7.5 14.9 18 6.2 0.0 4.8 5 0 0 5 5 4 0 Complex1_LYR-like TPR_3 PF07720.12 KFP13049.1 - 8.5 6.5 22.3 5.9 7.0 5.3 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MRVI1 PF05781.12 KFP13050.1 - 3.2e-219 729.1 14.2 4.3e-219 728.7 14.2 1.2 1 0 0 1 1 1 1 MRVI1 protein Gastrin PF00918.17 KFP13050.1 - 0.16 12.9 2.6 2 9.4 0.0 3.1 2 0 0 2 2 2 0 Gastrin/cholecystokinin family PEP-utilisers_N PF05524.13 KFP13050.1 - 0.86 9.8 4.0 2.3 8.4 2.4 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Xlink PF00193.17 KFP13051.1 - 3.6e-21 75.4 0.2 8.1e-21 74.2 0.2 1.6 1 0 0 1 1 1 1 Extracellular link domain Comm PF15957.5 KFP13051.1 - 0.0025 18.2 0.2 0.0065 16.8 0.1 1.8 1 1 1 2 2 2 1 Commissureless MGC-24 PF05283.11 KFP13051.1 - 0.0025 18.3 0.1 0.0025 18.3 0.1 2.1 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4834 PF16118.5 KFP13051.1 - 0.0041 18.1 0.1 0.0077 17.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4446 PF14584.6 KFP13051.1 - 0.0055 16.7 0.3 0.0096 15.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) OSTbeta PF15048.6 KFP13051.1 - 0.014 15.5 0.6 0.028 14.5 0.2 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein MFS_Mycoplasma PF07672.13 KFP13051.1 - 0.028 13.7 0.2 0.037 13.3 0.2 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter vMSA PF00695.19 KFP13051.1 - 0.043 12.9 0.2 0.057 12.5 0.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus STT3 PF02516.14 KFP13051.1 - 0.057 12.3 0.1 0.073 12.0 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit DcuC PF03606.15 KFP13051.1 - 0.064 11.7 0.0 0.13 10.6 0.0 1.4 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Nucleoside_tran PF01733.18 KFP13051.1 - 0.066 12.6 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Nucleoside transporter Phage_holin_3_6 PF07332.11 KFP13051.1 - 0.098 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4330 PF14221.6 KFP13051.1 - 0.1 12.8 0.2 9 6.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) PsbR PF04725.12 KFP13051.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR zf-C3HC4_3 PF13920.6 KFP13052.1 - 7.8e-11 41.7 11.8 1.3e-10 41.0 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP13052.1 - 2.6e-09 37.2 15.2 4.9e-09 36.4 15.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP13052.1 - 4.3e-09 36.1 14.7 7.5e-09 35.3 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP13052.1 - 1.6e-07 31.1 11.7 3.3e-07 30.1 11.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP13052.1 - 1.1e-06 28.4 13.9 2.1e-06 27.5 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP13052.1 - 5.3e-06 26.4 12.0 1.2e-05 25.2 12.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP13052.1 - 0.00012 21.9 14.3 0.00052 19.9 13.9 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP13052.1 - 0.00035 20.8 13.7 0.00088 19.5 13.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP13052.1 - 0.0055 16.8 10.6 0.015 15.4 10.6 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Gp138_N PF18352.1 KFP13052.1 - 0.041 13.9 0.3 2 8.6 0.2 2.4 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain Sulfotransfer_2 PF03567.14 KFP13052.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.6 1 1 1 2 2 2 0 Sulfotransferase family zf-ANAPC11 PF12861.7 KFP13052.1 - 0.17 12.0 9.1 0.36 10.9 9.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFP13052.1 - 0.24 11.2 12.7 0.52 10.2 12.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFP13052.1 - 1.8 8.4 15.8 0.94 9.3 12.6 2.2 2 1 0 2 2 2 0 RING-like zinc finger A_deaminase PF00962.22 KFP13053.1 - 2.4e-124 414.9 0.1 8.1e-124 413.2 0.1 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase PH PF00169.29 KFP13054.1 - 3.6e-18 66.0 1.3 8.3e-18 64.8 1.3 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP13054.1 - 0.0014 19.0 5.0 0.0014 19.0 5.0 3.3 3 1 0 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.10 KFP13054.1 - 0.071 13.5 4.0 0.11 12.8 0.0 3.0 2 1 1 3 3 3 0 Plant pleckstrin homology-like region Pkinase PF00069.25 KFP13055.1 - 3.8e-54 183.8 0.0 5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP13055.1 - 2.3e-21 76.3 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M74 PF03411.13 KFP13055.1 - 0.11 12.1 0.3 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Penicillin-insensitive murein endopeptidase zf-H2C2_2 PF13465.6 KFP13056.1 - 1e-35 120.6 49.8 9.4e-08 32.2 0.5 7.6 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP13056.1 - 3.1e-30 102.9 47.6 2.3e-06 27.7 1.2 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP13056.1 - 2.6e-19 68.2 43.6 0.0029 18.3 0.6 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger CopK PF11525.8 KFP13056.1 - 5.9e-07 29.0 3.5 1.7 8.4 0.0 6.0 4 2 2 6 6 6 2 Copper resistance protein K zf-C2H2_8 PF15909.5 KFP13056.1 - 2.5e-06 27.7 15.9 0.013 15.8 4.1 3.5 1 1 3 4 4 4 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP13056.1 - 3.5e-05 24.0 16.7 1.2 9.5 0.5 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP13056.1 - 9.3e-05 22.6 24.8 0.11 12.7 0.4 6.1 1 1 4 6 6 6 3 Aberrant zinc-finger FOXP-CC PF16159.5 KFP13056.1 - 0.0011 19.6 17.3 0.28 11.8 0.8 7.0 4 2 4 8 8 8 1 FOXP coiled-coil domain FecR PF04773.13 KFP13056.1 - 0.0047 17.5 2.9 0.46 11.2 0.0 4.0 2 1 1 3 3 3 1 FecR protein zf-TRAF PF02176.18 KFP13056.1 - 0.019 15.6 1.4 0.019 15.6 1.4 3.8 2 2 2 4 4 4 0 TRAF-type zinc finger SNARE_assoc PF09335.11 KFP13057.1 - 2.8e-22 79.4 6.1 2.8e-22 79.4 6.1 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF5305 PF17231.2 KFP13057.1 - 0.17 11.3 0.2 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TMEM208_SND2 PF05620.11 KFP13057.1 - 0.22 11.3 5.6 0.36 10.6 0.6 2.6 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Oleosin PF01277.17 KFP13057.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.8 2 1 1 3 3 3 0 Oleosin FXa_inhibition PF14670.6 KFP13059.1 - 2e-62 207.2 175.7 2.1e-11 43.9 9.9 11.5 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP13059.1 - 9.4e-39 131.0 75.9 2.6e-08 33.6 1.0 11.4 11 0 0 11 11 11 7 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 KFP13059.1 - 4.1e-26 90.5 31.3 1.3e-14 53.7 8.3 4.4 4 0 0 4 4 4 2 Putative ephrin-receptor like EGF_CA PF07645.15 KFP13059.1 - 5.5e-25 87.3 166.6 2.3e-07 30.9 5.3 11.7 12 0 0 12 12 12 6 Calcium-binding EGF domain EGF_3 PF12947.7 KFP13059.1 - 2.1e-22 79.0 136.0 4e-09 36.5 6.9 10.7 9 1 0 9 9 9 8 EGF domain CUB PF00431.20 KFP13059.1 - 5.6e-20 71.7 0.2 3.6e-19 69.1 0.0 2.4 2 0 0 2 2 2 1 CUB domain EGF PF00008.27 KFP13059.1 - 6.5e-17 61.5 132.5 0.00026 21.2 4.0 11.7 10 1 1 11 11 11 8 EGF-like domain DUF4375 PF14300.6 KFP13059.1 - 0.0028 17.9 0.3 5.6 7.3 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4375) Plasmod_Pvs28 PF06247.11 KFP13059.1 - 0.0031 17.8 19.9 0.0067 16.7 4.0 10.6 10 0 0 10 10 10 3 Pvs28 EGF domain hEGF PF12661.7 KFP13059.1 - 0.0094 16.6 13.8 0.017 15.8 5.3 12.5 10 1 0 10 10 10 4 Human growth factor-like EGF Asp_protease PF09668.10 KFP13060.1 - 1.2e-09 38.1 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFP13060.1 - 2.5e-08 34.3 0.0 5.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFP13060.1 - 3e-06 27.8 0.0 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 KFP13060.1 - 0.04 13.7 0.0 0.052 13.3 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease Tmemb_9 PF05434.11 KFP13061.1 - 9.7e-50 168.2 0.4 1.2e-49 168.0 0.4 1.1 1 0 0 1 1 1 1 TMEM9 HLH PF00010.26 KFP13062.1 - 6.4e-17 61.3 3.1 8.2e-17 60.9 3.1 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cas9-BH PF16593.5 KFP13062.1 - 0.016 14.9 0.4 0.038 13.7 0.4 1.5 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF4537 PF15057.6 KFP13063.1 - 8.7e-28 96.8 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DENN PF02141.21 KFP13064.1 - 6.9e-59 198.9 0.7 1.8e-58 197.6 0.7 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP13064.1 - 7.3e-17 61.9 0.1 2.2e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP13064.1 - 2.3e-12 46.7 3.2 6.7e-12 45.2 3.2 1.9 1 0 0 1 1 1 1 dDENN domain Ribosomal_L27A PF00828.19 KFP13065.1 - 1.7e-25 90.1 0.0 2e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A LIM PF00412.22 KFP13066.1 - 2.4e-30 104.5 21.9 3.8e-15 55.9 8.1 2.0 2 0 0 2 2 2 2 LIM domain RIC3 PF15361.6 KFP13067.1 - 4.4e-32 111.5 0.0 1.4e-31 109.8 0.0 1.9 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 GON PF08685.11 KFP13068.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 GON domain Tub PF01167.18 KFP13069.1 - 2.8e-96 322.0 0.4 1.7e-95 319.4 0.0 2.1 2 1 0 2 2 2 1 Tub family Tub_N PF16322.5 KFP13069.1 - 1.9e-62 211.4 26.8 2.6e-62 210.9 26.8 1.2 1 0 0 1 1 1 1 Tubby N-terminal UpxZ PF06603.11 KFP13069.1 - 0.17 12.2 0.8 10 6.5 0.1 2.9 2 2 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Ras PF00071.22 KFP13070.1 - 1.9e-48 164.1 0.3 2.2e-48 163.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13070.1 - 4.6e-12 46.2 0.0 1.6e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP13070.1 - 2.2e-06 27.3 0.0 2.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFP13070.1 - 7.8e-06 25.4 0.1 9.3e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KFP13070.1 - 0.0087 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Adaptin_N PF01602.20 KFP13071.1 - 1.5e-122 409.9 8.4 2.2e-122 409.3 8.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFP13071.1 - 7.7e-61 204.1 0.3 1.6e-60 203.1 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFP13071.1 - 2.9e-60 201.9 0.1 1.6e-59 199.5 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFP13071.1 - 4.1e-08 33.4 12.3 3.2e-05 24.0 0.1 4.2 2 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP13071.1 - 8.7e-08 31.8 0.2 0.035 14.4 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFP13071.1 - 1.5e-07 31.7 4.2 0.033 14.6 0.0 6.0 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 KFP13071.1 - 5.2e-06 26.8 0.4 1.1 9.8 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 KFP13071.1 - 0.00023 21.1 0.1 1.7 8.8 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 KFP13071.1 - 0.00029 20.5 2.0 0.0053 16.4 0.0 3.4 2 1 2 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF5578 PF17741.1 KFP13071.1 - 0.0068 15.9 4.9 0.95 8.8 0.2 3.3 1 1 2 3 3 3 2 Family of unknown function (DUF5578) PDEase_I PF00233.19 KFP13073.1 - 8.1e-67 225.4 0.4 4.6e-62 209.9 0.0 2.6 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Sigma70_ner PF04546.13 KFP13073.1 - 0.00055 19.9 0.6 0.00055 19.9 0.6 1.9 3 0 0 3 3 3 1 Sigma-70, non-essential region p450 PF00067.22 KFP13074.1 - 3.2e-116 388.8 0.0 3.6e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Calc_CGRP_IAPP PF00214.19 KFP13075.1 - 2.2e-42 144.3 0.3 2.4e-42 144.1 0.3 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family TA_inhibitor PF17574.2 KFP13075.1 - 0.072 13.1 0.1 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) DUF1615 PF07759.12 KFP13075.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) INSC_LBD PF16748.5 KFP13076.1 - 9.3e-28 95.4 5.0 2e-27 94.3 5.0 1.5 1 0 0 1 1 1 1 Inscuteable LGN-binding domain Arm PF00514.23 KFP13076.1 - 0.0071 16.4 0.3 0.0071 16.4 0.3 5.2 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat CMS1 PF14617.6 KFP13076.1 - 0.65 9.3 3.4 2.7 7.2 0.0 3.2 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit SPOB_ab PF14682.6 KFP13076.1 - 2.6 8.1 9.3 2.3 8.4 2.6 3.0 2 1 1 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal HMG_box PF00505.19 KFP13078.1 - 1.5e-22 79.8 4.5 5.5e-22 78.0 4.5 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP13078.1 - 2e-09 37.9 1.1 2e-09 37.9 1.1 3.4 3 0 0 3 3 3 1 HMG-box domain MPS2 PF17060.5 KFP13078.1 - 2.5 7.3 17.1 0.11 11.7 11.3 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 DivIVA PF05103.13 KFP13078.1 - 9.8 6.3 18.7 11 6.1 13.6 2.5 2 0 0 2 2 2 0 DivIVA protein SMAP PF15477.6 KFP13081.1 - 0.00026 21.9 0.6 0.00026 21.9 0.6 2.4 2 1 0 2 2 2 1 Small acidic protein family PNISR PF15996.5 KFP13081.1 - 0.2 11.9 13.7 0.24 11.7 13.7 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RNA_polI_A34 PF08208.11 KFP13081.1 - 1 9.4 12.3 1.4 9.0 12.3 1.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.17 KFP13081.1 - 1.3 9.2 6.7 1.5 8.9 6.7 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.12 KFP13081.1 - 1.7 6.8 15.9 2 6.5 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 KFP13081.1 - 2.5 7.0 17.9 2.7 6.9 17.9 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 KFP13081.1 - 2.6 6.2 13.2 2.9 6.1 13.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1980 PF09323.10 KFP13081.1 - 3 7.7 4.6 3.7 7.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spore_coat_CotO PF14153.6 KFP13081.1 - 3.2 7.7 11.0 4.2 7.3 11.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 KFP13081.1 - 9.3 4.9 11.2 11 4.6 11.2 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_S13_N PF08069.12 KFP13083.1 - 7.1e-26 90.0 0.1 1.3e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFP13083.1 - 4.2e-15 55.7 1.2 7.2e-15 55.0 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KFP13083.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain EF-hand_7 PF13499.6 KFP13084.1 - 2e-11 44.1 3.4 2e-11 44.1 3.4 3.9 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP13084.1 - 1.1e-08 34.0 5.2 0.00021 20.6 0.4 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP13084.1 - 2.6e-07 30.0 3.1 1.3e-05 24.7 0.2 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFP13084.1 - 0.00042 19.7 3.6 0.0097 15.4 0.4 4.1 4 0 0 4 4 4 1 EF hand Histone_HNS PF00816.21 KFP13084.1 - 0.04 14.7 0.4 0.04 14.7 0.4 3.5 2 1 0 3 3 3 0 H-NS histone family EF-hand_8 PF13833.6 KFP13084.1 - 0.078 12.8 1.8 3 7.8 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain pair DivIC PF04977.15 KFP13084.1 - 2.8 7.8 11.0 13 5.7 11.0 2.1 1 0 0 1 1 1 0 Septum formation initiator MctB PF11382.8 KFP13084.1 - 3.8 7.1 6.8 7.5 6.2 6.8 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB IRK_C PF17655.1 KFP13085.1 - 2.9e-69 232.1 0.0 3.8e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP13085.1 - 1.1e-56 190.6 0.4 1.7e-56 190.0 0.4 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain EI24 PF07264.11 KFP13085.1 - 0.037 14.3 2.1 0.057 13.7 2.1 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Cupin_2 PF07883.11 KFP13085.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Ion_trans_2 PF07885.16 KFP13085.1 - 0.36 10.8 6.2 0.052 13.5 1.1 2.0 2 0 0 2 2 2 0 Ion channel ABC_membrane PF00664.23 KFP13086.1 - 2.9e-76 256.7 37.0 7.6e-42 143.8 3.6 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP13086.1 - 4.9e-52 176.1 0.1 2.2e-24 86.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KFP13086.1 - 6.7e-11 42.0 1.9 0.00041 19.9 0.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFP13086.1 - 4.7e-05 23.4 3.6 1 9.1 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP13086.1 - 0.00028 20.8 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFP13086.1 - 0.0003 20.5 0.6 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KFP13086.1 - 0.00033 19.6 1.0 0.066 12.0 0.0 3.0 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KFP13086.1 - 0.0016 18.1 0.0 0.084 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFP13086.1 - 0.0021 18.2 0.2 0.71 10.0 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KFP13086.1 - 0.0027 17.5 0.4 0.87 9.3 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_23 PF13476.6 KFP13086.1 - 0.0063 17.0 4.8 0.69 10.4 1.8 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP13086.1 - 0.021 15.1 0.7 4.2 7.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KFP13086.1 - 0.023 14.4 0.1 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KFP13086.1 - 0.051 12.9 0.2 8.6 5.6 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 KFP13086.1 - 0.058 12.9 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KFP13086.1 - 0.07 12.8 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 KFP13086.1 - 0.079 12.0 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFP13086.1 - 0.09 12.0 0.1 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KFP13086.1 - 0.11 12.2 0.6 0.52 10.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFP13086.1 - 0.13 12.7 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KFP13086.1 - 0.28 11.2 5.2 0.38 10.8 0.0 2.8 3 0 0 3 3 3 0 Dynamin family VWD PF00094.25 KFP13087.1 - 7.6e-79 263.5 9.5 1.1e-35 123.3 0.4 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 KFP13087.1 - 1.9e-41 140.3 58.1 1.1e-15 57.8 5.8 9.5 9 0 0 9 9 9 4 C8 domain TIL PF01826.17 KFP13087.1 - 2.1e-13 50.3 81.0 1e-10 41.7 20.5 16.7 15 2 2 17 17 17 5 Trypsin Inhibitor like cysteine rich domain AbfB PF05270.13 KFP13087.1 - 7.4e-08 32.5 0.1 1.5e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain VWC PF00093.18 KFP13087.1 - 0.0018 18.5 3.1 0.0018 18.5 3.1 17.7 12 3 6 18 18 18 3 von Willebrand factor type C domain Ferritin PF00210.24 KFP13088.1 - 6.5e-14 52.1 0.1 9.8e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ion_trans PF00520.31 KFP13090.1 - 8.1e-45 153.0 12.8 1e-44 152.6 12.8 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP13090.1 - 6.1e-26 90.6 0.0 1.5e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP13090.1 - 2.7e-11 43.3 2.6 2.7e-11 43.3 2.6 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFP13090.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain RCC1 PF00415.18 KFP13091.1 - 3.2e-52 174.9 18.3 7.2e-11 42.5 0.1 6.7 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP13091.1 - 5.1e-34 115.4 37.0 9.8e-10 38.0 0.3 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 KFP13091.1 - 0.079 13.3 2.0 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Biopterin_H PF00351.21 KFP13092.1 - 2.7e-177 588.7 0.0 3.3e-177 588.5 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KFP13092.1 - 1.1e-06 28.3 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain Seryl_tRNA_N PF02403.22 KFP13092.1 - 0.031 14.5 0.7 7.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5370 PF17340.2 KFP13092.1 - 0.033 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5370) IKKbetaNEMObind PF12179.8 KFP13093.1 - 0.21 11.6 1.6 0.37 10.9 0.6 1.9 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain SAA PF00277.18 KFP13094.1 - 1e-45 154.3 8.1 1.1e-45 154.2 8.1 1.0 1 0 0 1 1 1 1 Serum amyloid A protein ANAPC4_WD40 PF12894.7 KFP13095.1 - 0.016 15.5 0.2 0.073 13.4 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PH_TFIIH PF08567.11 KFP13096.1 - 4.8e-25 87.7 0.0 9.2e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KFP13096.1 - 3.4e-23 81.4 3.3 1.2e-16 60.5 0.0 3.3 3 0 0 3 3 3 2 BSD domain Ldh_1_N PF00056.23 KFP13098.1 - 4e-47 159.8 0.2 5.7e-47 159.4 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFP13098.1 - 1.4e-21 77.2 0.0 4.4e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KFP13098.1 - 0.013 15.1 0.2 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase UEV PF05743.13 KFP13099.1 - 4.5e-48 162.1 1.8 2.2e-47 159.9 0.3 2.2 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.10 KFP13099.1 - 3.8e-28 97.2 0.1 6.7e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain DUF3450 PF11932.8 KFP13099.1 - 0.00068 19.0 8.4 0.0012 18.2 8.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) UQ_con PF00179.26 KFP13099.1 - 0.00074 19.2 0.3 0.00074 19.2 0.3 2.1 2 0 0 2 2 1 1 Ubiquitin-conjugating enzyme Macoilin PF09726.9 KFP13099.1 - 0.017 13.8 3.6 0.022 13.3 3.6 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 KFP13099.1 - 0.019 15.5 11.8 0.019 15.5 11.8 1.6 2 0 0 2 2 1 0 Apg6 coiled-coil region GPS2_interact PF15784.5 KFP13099.1 - 0.026 15.0 9.0 0.096 13.1 9.0 1.9 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF1640 PF07798.11 KFP13099.1 - 0.027 14.5 7.1 0.027 14.5 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ERM PF00769.19 KFP13099.1 - 0.052 13.3 13.9 0.092 12.5 13.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fzo_mitofusin PF04799.13 KFP13099.1 - 0.061 12.9 4.5 0.12 11.9 4.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region Exonuc_VII_L PF02601.15 KFP13099.1 - 0.075 12.6 1.5 0.096 12.2 1.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFP13099.1 - 0.082 11.5 5.0 0.11 11.0 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 KFP13099.1 - 0.11 10.5 2.1 0.15 10.0 2.1 1.1 1 0 0 1 1 1 0 Prominin SlyX PF04102.12 KFP13099.1 - 0.15 12.7 12.7 0.14 12.8 3.4 3.2 2 1 1 3 3 3 0 SlyX DUF3552 PF12072.8 KFP13099.1 - 0.17 11.3 10.2 0.26 10.7 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KFP13099.1 - 0.18 10.7 10.4 0.26 10.1 10.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3782 PF12644.7 KFP13099.1 - 0.36 11.0 5.9 5 7.4 0.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3782) TMPIT PF07851.13 KFP13099.1 - 0.45 9.7 3.6 0.65 9.2 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 KFP13099.1 - 0.51 10.6 12.7 0.81 10.0 5.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KFP13099.1 - 0.56 10.4 5.0 1 9.5 5.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP13099.1 - 0.6 10.2 4.8 1.1 9.3 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFP13099.1 - 0.61 10.5 11.8 1 9.8 0.8 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 KFP13099.1 - 0.96 9.3 8.1 0.79 9.5 5.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF724 PF05266.14 KFP13099.1 - 0.98 9.2 9.5 1.7 8.4 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFP13099.1 - 1 7.2 3.0 1.3 6.8 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_III_AB PF09548.10 KFP13099.1 - 1.4 9.0 4.9 2.1 8.4 4.9 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NPV_P10 PF05531.12 KFP13099.1 - 1.6 9.3 5.7 4.1 7.9 3.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PCRF PF03462.18 KFP13099.1 - 2.2 8.1 6.4 4.1 7.2 6.4 1.4 1 0 0 1 1 1 0 PCRF domain Atg14 PF10186.9 KFP13099.1 - 2.6 7.1 5.6 4 6.4 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KFP13099.1 - 2.8 7.8 14.2 1.9 8.3 2.2 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 KFP13099.1 - 3.2 8.3 7.9 27 5.3 7.1 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 KFP13099.1 - 3.7 7.6 8.3 9.9 6.2 5.6 2.2 2 0 0 2 2 2 0 Laminin Domain II Prefoldin PF02996.17 KFP13099.1 - 5.1 7.0 10.3 5 7.1 2.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit BRE1 PF08647.11 KFP13099.1 - 5.7 7.1 17.7 3.1 7.9 13.9 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Prefoldin_2 PF01920.20 KFP13099.1 - 6.7 6.7 15.0 5.5 7.0 2.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 KFP13099.1 - 7.8 6.6 18.1 9.9 6.2 15.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UEV PF05743.13 KFP13100.1 - 3.2e-42 143.2 0.1 5.1e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 UEV domain Ldh_1_N PF00056.23 KFP13100.1 - 3.4e-22 79.1 0.4 5.7e-22 78.3 0.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFP13100.1 - 1.4e-11 44.6 0.1 2.5e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3HCDH_N PF02737.18 KFP13100.1 - 0.11 12.3 0.5 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFP13100.1 - 0.19 12.3 1.4 0.95 10.1 0.3 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SPT2 PF08243.11 KFP13101.1 - 4.5e-22 78.7 22.5 4.5e-22 78.7 22.5 4.0 4 1 0 4 4 4 1 SPT2 chromatin protein YhhN PF07947.14 KFP13102.1 - 9.9e-46 155.7 23.6 9.9e-46 155.7 23.6 1.3 1 1 0 1 1 1 1 YhhN family YtpI PF14007.6 KFP13102.1 - 1.2 9.3 7.2 0.26 11.4 0.3 2.9 2 1 1 3 3 3 0 YtpI-like protein Y_phosphatase PF00102.27 KFP13103.1 - 1.9e-73 246.9 1.0 3.6e-73 246.0 1.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP13103.1 - 1.1e-06 28.5 0.0 3.6e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP13103.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family YccF PF03733.13 KFP13103.1 - 0.0069 17.1 1.0 0.028 15.1 1.0 2.1 1 0 0 1 1 1 1 Inner membrane component domain PTPlike_phytase PF14566.6 KFP13103.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CPSase_L_D2 PF02786.17 KFP13103.1 - 0.16 11.5 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Oxysterol_BP PF01237.18 KFP13104.1 - 2.5e-84 283.3 5.3 2e-82 277.0 5.3 2.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFP13104.1 - 1.3e-10 41.7 0.2 4.3e-09 36.8 0.0 3.0 2 0 0 2 2 2 1 PH domain TNFR_c6 PF00020.18 KFP13105.1 - 9.2e-12 45.2 28.1 1.3e-11 44.7 6.7 3.5 2 1 0 3 3 3 3 TNFR/NGFR cysteine-rich region tRNA-synt_1e PF01406.19 KFP13106.1 - 8.9e-129 429.1 0.3 8.9e-129 429.1 0.3 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFP13106.1 - 3.3e-07 29.4 2.1 0.00042 19.2 0.2 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFP13106.1 - 0.003 15.9 1.0 0.011 14.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) WGG PF10273.9 KFP13106.1 - 0.12 13.0 0.8 0.51 11.0 0.2 2.4 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 NAP PF00956.18 KFP13107.1 - 8.2e-107 356.4 5.1 8.2e-107 356.4 5.1 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Muted PF14942.6 KFP13107.1 - 0.0076 16.6 5.9 0.046 14.1 0.9 2.5 1 1 1 2 2 2 2 Organelle biogenesis, Muted-like protein ING PF12998.7 KFP13107.1 - 0.2 12.2 2.0 1.4 9.5 0.0 2.8 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF3450 PF11932.8 KFP13107.1 - 5.5 6.2 7.3 2.8 7.2 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MFS_1 PF07690.16 KFP13109.1 - 3.5e-29 101.8 42.9 5.5e-19 68.3 15.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP13109.1 - 5e-06 25.6 25.8 0.0012 17.7 11.4 3.0 2 1 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 KFP13109.1 - 0.0007 18.1 18.5 0.095 11.1 7.2 3.7 1 1 1 3 3 3 3 Transmembrane secretion effector Ion_trans PF00520.31 KFP13114.1 - 2.5e-26 92.4 10.4 3.2e-26 92.1 10.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP13114.1 - 9.7e-12 44.7 6.0 9.7e-12 44.7 6.0 2.3 2 1 1 3 3 3 1 Ion channel CD225 PF04505.12 KFP13114.1 - 0.025 14.7 0.2 0.51 10.5 0.1 2.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein LSDAT_euk PF18139.1 KFP13115.1 - 1.3e-51 175.5 0.0 3e-51 174.4 0.0 1.5 2 0 0 2 2 2 1 SLOG in TRPM LSDAT_prok PF18171.1 KFP13115.1 - 1.7e-14 53.5 0.0 3.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFP13115.1 - 2.8e-11 43.1 22.7 1.2e-10 41.1 22.7 2.0 1 1 0 1 1 1 1 Ion transport protein TSSC4 PF15264.6 KFP13116.1 - 1.3e-27 96.6 0.2 2.7e-27 95.5 0.2 1.6 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 MAM PF00629.23 KFP13118.1 - 2.1e-131 434.0 0.0 4.2e-43 147.0 0.0 4.0 4 0 0 4 4 4 4 MAM domain, meprin/A5/mu PPTA PF01239.22 KFP13119.1 - 2.3e-23 81.1 11.4 1.8e-07 30.6 0.2 6.4 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat PID PF00640.23 KFP13120.1 - 5.3e-52 175.6 0.7 1.2e-51 174.4 0.7 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFP13120.1 - 7e-28 96.8 10.3 2e-15 56.9 1.0 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFP13120.1 - 1.9e-16 59.6 0.3 4.2e-08 32.9 0.1 3.2 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 KFP13120.1 - 5.1e-07 29.9 0.1 6.6e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 PDZ domain NRho PF16733.5 KFP13120.1 - 0.066 13.3 0.2 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Rhomboid N-terminal domain Flavokinase PF01687.17 KFP13121.1 - 1.3e-25 89.8 0.0 1.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase BNIP2 PF12496.8 KFP13122.1 - 7.4e-43 146.2 3.5 9.8e-43 145.8 3.5 1.1 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFP13122.1 - 4e-31 108.0 0.3 6.7e-31 107.3 0.3 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFP13122.1 - 5.2e-10 39.3 0.5 9.5e-10 38.4 0.5 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain DHHA2 PF02833.14 KFP13123.1 - 0.0031 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DUF1048 PF06304.11 KFP13125.1 - 0.049 14.1 5.4 0.1 13.0 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1048) PRMT5 PF05185.16 KFP13125.1 - 2.8 7.8 6.0 4.5 7.1 5.8 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase SLBP_RNA_bind PF15247.6 KFP13125.1 - 6.9 6.9 7.7 7.5 6.8 0.4 2.8 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain GON PF08685.11 KFP13127.1 - 0.27 11.1 0.0 0.29 11.0 0.0 1.0 1 0 0 1 1 1 0 GON domain NMDAR2_C PF10565.9 KFP13129.1 - 1.2e-270 900.2 33.4 1.4e-270 899.9 33.4 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.26 KFP13129.1 - 1.9e-34 118.7 0.1 1.9e-34 118.7 0.1 2.1 3 0 0 3 3 3 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP13129.1 - 7.7e-31 106.7 0.1 4.2e-30 104.3 0.1 2.1 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP13129.1 - 7.1e-21 74.7 0.0 2.4e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFP13129.1 - 7.9e-09 35.1 0.1 4.8e-08 32.5 0.1 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region PMP22_Claudin PF00822.20 KFP13134.1 - 3.5e-49 166.9 15.2 4e-49 166.7 15.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP13134.1 - 1.6e-11 44.3 7.3 1.6e-11 44.3 7.3 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP13134.1 - 0.00069 19.5 11.9 0.0013 18.6 11.8 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 KFP13134.1 - 0.0022 17.7 13.9 0.0022 17.7 13.9 3.2 1 1 0 2 2 2 1 SUR7/PalI family Claudin_3 PF06653.11 KFP13134.1 - 0.0024 17.8 15.9 0.007 16.3 15.9 1.7 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF2721 PF11026.8 KFP13134.1 - 0.021 14.7 1.8 0.021 14.7 1.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Trp_oprn_chp PF09534.10 KFP13134.1 - 0.059 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2339 PF10101.9 KFP13134.1 - 0.12 11.0 6.5 0.16 10.5 6.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) HisKA_7TM PF16927.5 KFP13134.1 - 0.4 10.7 10.3 0.79 9.7 10.3 1.6 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF3852 PF12963.7 KFP13134.1 - 1.2 9.5 7.7 0.071 13.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) DUF202 PF02656.15 KFP13134.1 - 1.5 9.4 8.7 2.9 8.4 0.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) 7TMR-DISM_7TM PF07695.11 KFP13134.1 - 2 8.3 18.3 17 5.3 18.1 2.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4064 PF13273.6 KFP13134.1 - 3.7 7.9 15.6 0.2 12.0 1.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ParA PF10609.9 KFP13136.1 - 5.3e-86 288.1 0.0 5.9e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_26 PF13500.6 KFP13136.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KFP13136.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PcrB PF01884.17 KFP13136.1 - 0.067 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PcrB family Fer4_NifH PF00142.18 KFP13136.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TF_Zn_Ribbon PF08271.12 KFP13136.1 - 0.11 12.0 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Pam16 PF03656.13 KFP13139.1 - 0.088 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Pam16 NACHT PF05729.12 KFP13140.1 - 4.9e-25 88.4 0.0 1.3e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 KFP13140.1 - 3.5e-16 57.8 7.6 0.00011 22.0 0.1 5.3 5 0 0 5 5 5 4 Leucine Rich repeat NLRC4_HD2 PF17776.1 KFP13140.1 - 5.3e-12 46.4 1.5 5.3e-12 46.4 1.5 2.3 2 0 0 2 2 2 1 NLRC4 helical domain HD2 LRR_4 PF12799.7 KFP13140.1 - 7.6e-11 42.1 6.2 3.8e-06 27.2 0.6 4.7 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP13140.1 - 3.2e-06 26.8 0.3 0.0083 15.6 0.1 3.1 1 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFP13140.1 - 3.9e-06 26.5 6.2 0.003 17.3 2.1 4.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KFP13140.1 - 0.00027 21.0 0.8 45 5.2 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat Dexa_ind PF15198.6 KFP13141.1 - 2.3e-43 146.2 10.7 2.5e-43 146.0 10.7 1.0 1 0 0 1 1 1 1 Dexamethasone-induced FPL PF09758.9 KFP13142.1 - 1.6e-61 206.6 12.2 3.2e-61 205.7 12.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF4462 PF14692.6 KFP13143.1 - 0.12 11.9 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) SH2 PF00017.24 KFP13145.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.5 2 0 0 2 2 2 1 SH2 domain SH2_2 PF14633.6 KFP13145.1 - 0.22 10.9 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Spp-24 PF07448.11 KFP13148.1 - 9.7e-20 70.5 0.2 1.5e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Cathelicidins PF00666.17 KFP13148.1 - 8e-08 32.5 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Cathelicidin Cystatin PF00031.21 KFP13148.1 - 0.0045 17.2 0.0 0.0066 16.7 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain LSDAT_euk PF18139.1 KFP13150.1 - 7.4e-62 209.1 0.0 1.2e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFP13150.1 - 1.8e-15 56.7 0.0 3.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFP13150.1 - 1.2e-14 54.2 21.2 1.2e-14 54.2 21.2 2.3 2 1 0 2 2 2 1 Ion transport protein ArfGap PF01412.18 KFP13154.1 - 2.8e-40 137.0 0.1 6.6e-40 135.8 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 KFP13154.1 - 3.1e-18 65.9 0.0 5.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 KFP13154.1 - 1.5e-11 44.7 0.1 2.9e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH PF00169.29 KFP13154.1 - 4.9e-11 43.1 3.0 9.9e-05 22.8 0.1 3.5 3 0 0 3 3 3 2 PH domain Ank PF00023.30 KFP13154.1 - 6.4e-10 39.0 0.1 4.1e-06 27.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP13154.1 - 2.9e-09 37.0 0.3 8.5e-09 35.5 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP13154.1 - 5.4e-08 33.2 0.1 6.5e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP13154.1 - 1.4e-05 25.1 0.3 0.00048 20.4 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeat Roc PF08477.13 KFP13154.1 - 0.00042 20.5 0.0 0.0023 18.2 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PH_6 PF15406.6 KFP13154.1 - 0.0036 17.6 0.3 0.0036 17.6 0.3 1.8 2 0 0 2 2 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP13154.1 - 0.037 14.4 7.9 0.72 10.3 0.3 3.4 4 0 0 4 4 3 0 Pleckstrin homology domain MAGI_u1 PF16663.5 KFP13154.1 - 0.046 13.8 1.1 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Unstructured region on MAGI PH_8 PF15409.6 KFP13154.1 - 0.087 13.1 0.5 8.1 6.8 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain AAA PF00004.29 KFP13155.1 - 1.7e-14 54.3 0.0 4.7e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 KFP13155.1 - 5.6e-06 25.7 0.0 1.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3135 PF11333.8 KFP13155.1 - 9.4 6.6 9.8 0.21 11.9 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) RVT_1 PF00078.27 KFP13157.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CSN8_PSD8_EIF3K PF10075.9 KFP13158.1 - 2.6e-36 124.7 0.0 3.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 KFP13158.1 - 0.035 14.6 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 PCI domain Ras PF00071.22 KFP13159.1 - 3.2e-42 143.9 0.0 3.7e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13159.1 - 3.4e-20 72.5 0.0 5.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP13159.1 - 4.2e-10 39.4 0.0 5.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family LRRFIP PF09738.9 KFP13161.1 - 1.9e-76 257.4 89.3 3.5e-44 151.5 24.4 6.0 2 1 2 4 4 4 3 LRRFIP family BRE1 PF08647.11 KFP13161.1 - 0.0017 18.4 10.1 0.0017 18.4 10.1 5.8 4 2 1 5 5 5 1 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KFP13161.1 - 0.012 16.1 11.1 0.012 16.1 11.1 5.1 2 1 3 5 5 5 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KFP13161.1 - 0.013 15.7 5.7 0.013 15.7 5.7 6.0 4 2 2 6 6 6 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 KFP13161.1 - 0.014 15.5 11.8 0.014 15.5 11.8 5.5 3 2 0 4 4 4 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KFP13161.1 - 0.082 13.1 25.2 0.88 9.8 0.9 5.8 5 1 0 5 5 5 0 Homeobox associated leucine zipper DUF3584 PF12128.8 KFP13161.1 - 0.77 7.2 48.0 0.005 14.4 16.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Tweety PF04906.13 KFP13161.1 - 1.5 7.4 18.4 0.35 9.5 3.3 3.9 2 2 3 5 5 5 0 Tweety UQ_con PF00179.26 KFP13163.1 - 2e-28 98.8 0.0 2.3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Methyltransf_11 PF08241.12 KFP13164.1 - 6.5e-25 87.6 0.0 1.6e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP13164.1 - 1.7e-22 79.9 0.0 3.8e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP13164.1 - 2.2e-15 56.8 0.0 3.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP13164.1 - 2.3e-12 46.8 0.0 3.9e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFP13164.1 - 7.6e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP13164.1 - 1.4e-11 44.6 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP13164.1 - 1.2e-07 31.8 0.0 3.1e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KFP13164.1 - 7.5e-06 24.8 0.0 9.7e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 KFP13164.1 - 8.9e-06 25.5 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KFP13164.1 - 5.5e-05 22.6 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KFP13164.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KFP13164.1 - 0.0017 17.4 0.0 0.0022 17.1 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 KFP13164.1 - 0.0017 17.9 0.0 0.0045 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KFP13164.1 - 0.0028 17.5 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 KFP13164.1 - 0.0038 16.7 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_N4_Mtase PF01555.18 KFP13164.1 - 0.007 16.1 0.0 3.3 7.4 0.0 2.5 2 1 0 2 2 2 2 DNA methylase Methyltransf_33 PF10017.9 KFP13164.1 - 0.016 14.4 0.0 0.029 13.5 0.0 1.6 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DREV PF05219.12 KFP13164.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 KFP13164.1 - 0.031 14.4 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 KFP13164.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase NodS PF05401.11 KFP13164.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MREG PF15812.5 KFP13165.1 - 2e-70 235.9 4.0 2.3e-70 235.7 4.0 1.0 1 0 0 1 1 1 1 Melanoregulin AIP3 PF03915.13 KFP13165.1 - 0.011 14.9 0.2 0.013 14.6 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 COG5 PF10392.9 KFP13165.1 - 0.038 14.2 0.3 0.053 13.7 0.3 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Lipoprotein_6 PF01441.19 KFP13165.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 Lipoprotein Kinesin PF00225.23 KFP13170.1 - 2.1e-95 319.5 0.3 3.3e-95 318.8 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP13170.1 - 2.7e-22 79.3 0.0 8.1e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 KFP13170.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KFP13170.1 - 0.033 13.9 0.3 0.33 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP13170.1 - 0.04 14.2 0.8 0.23 11.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KFP13170.1 - 0.068 13.2 6.0 0.21 11.5 0.2 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SKA2 PF16740.5 KFP13170.1 - 0.57 10.0 4.4 3.3 7.5 0.3 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 SRPRB PF09439.10 KFP13170.1 - 1.7 8.0 5.2 8.1 5.8 0.7 3.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit Mvb12 PF09452.10 KFP13170.1 - 1.8 9.0 5.2 0.72 10.3 0.4 2.7 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 SOAR PF16533.5 KFP13170.1 - 6.2 6.8 8.6 0.67 10.0 0.6 3.0 3 0 0 3 3 3 0 STIM1 Orai1-activating region SET PF00856.28 KFP13171.1 - 2e-18 67.4 0.1 2e-18 67.4 0.1 3.9 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KFP13171.1 - 1.8e-12 47.1 5.1 4.4e-12 45.8 5.1 1.7 1 0 0 1 1 1 1 AWS domain SRI PF08236.11 KFP13171.1 - 1.3e-11 44.4 1.4 6.3e-11 42.3 1.4 2.2 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 KFP13171.1 - 2.4e-11 43.5 3.6 6.8e-11 42.1 3.6 1.9 1 0 0 1 1 1 1 WW domain DUF3592 PF12158.8 KFP13171.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF3592) Glyco_hydro_38N PF01074.22 KFP13172.1 - 2.1e-81 273.5 5.4 3.6e-81 272.7 5.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFP13172.1 - 9e-27 94.5 0.8 1.6e-26 93.7 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFP13172.1 - 3.8e-18 65.4 0.0 9.3e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFP13172.1 - 2.1e-07 30.9 0.0 5.3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain WD40 PF00400.32 KFP13175.1 - 2.1e-07 31.5 4.7 1.6 9.7 0.1 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13175.1 - 0.0013 18.9 0.0 17 5.8 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain JAKMIP_CC3 PF16034.5 KFP13176.1 - 1.7e-85 286.0 20.8 1.7e-85 286.0 20.8 6.7 5 2 1 6 6 6 1 JAKMIP CC3 domain ADIP PF11559.8 KFP13176.1 - 0.0044 17.1 13.1 0.0044 17.1 13.1 8.5 5 4 5 10 10 10 2 Afadin- and alpha -actinin-Binding DUF1654 PF07867.11 KFP13176.1 - 0.025 14.3 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Amidohydro_1 PF01979.20 KFP13178.1 - 1.9e-33 116.3 0.0 2.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP13178.1 - 3.8e-10 39.8 0.0 3.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFP13178.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase BAG6 PF12057.8 KFP13179.1 - 0.041 13.6 7.5 0.74 9.5 0.2 2.9 2 0 0 2 2 2 0 BCL2-associated athanogene 6 PRESAN PF09687.10 KFP13179.1 - 0.98 10.0 22.2 0.76 10.3 2.4 3.7 3 0 0 3 3 3 0 Plasmodium RESA N-terminal EVC2_like PF12297.8 KFP13180.1 - 2.7e-182 606.2 27.6 2.7e-182 606.2 27.6 3.8 4 0 0 4 4 4 1 Ellis van Creveld protein 2 like protein Claudin_2 PF13903.6 KFP13180.1 - 0.06 13.1 2.8 0.36 10.5 0.6 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SAUGI PF06106.11 KFP13180.1 - 0.09 13.3 1.7 1.8 9.1 0.1 2.9 2 0 0 2 2 2 0 S. aureus uracil DNA glycosylase inhibitor Frag1 PF10277.9 KFP13180.1 - 1.1 8.8 5.1 0.22 11.1 0.6 1.9 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family IBV_3A PF03617.13 KFP13180.1 - 1.5 8.9 5.9 7.9 6.6 0.6 3.2 2 0 0 2 2 2 0 IBV 3A protein CYTL1 PF15153.6 KFP13181.1 - 9.5e-58 193.7 3.5 1.2e-57 193.4 3.5 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 DUF1599 PF07659.11 KFP13181.1 - 0.032 14.7 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 Myosin_head PF00063.21 KFP13182.1 - 6.7e-273 907.0 0.7 6.7e-273 907.0 0.7 3.6 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP13182.1 - 2.2e-153 512.6 279.0 2.7e-153 512.3 279.0 1.1 1 0 0 1 1 1 1 Myosin tail IQ PF00612.27 KFP13182.1 - 0.023 14.4 3.0 0.13 12.1 1.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP13182.1 - 0.066 13.5 0.0 0.066 13.5 0.0 6.1 3 2 1 5 5 5 0 AAA domain ATP-synt_ab PF00006.25 KFP13182.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Homeodomain PF00046.29 KFP13185.1 - 1.5e-20 72.8 5.1 2.2e-20 72.3 5.1 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP13185.1 - 0.2 11.1 0.5 0.91 9.0 0.2 2.0 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF2457 PF10446.9 KFP13185.1 - 9.5 5.2 7.8 11 5.0 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Syntaxin-18_N PF10496.9 KFP13188.1 - 1.4e-09 38.0 0.4 1.4e-09 38.0 0.4 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Phage_Integr_2 PF13009.6 KFP13188.1 - 0.00038 19.7 0.7 0.0006 19.0 0.7 1.3 1 0 0 1 1 1 1 Putative phage integrase CHIP_TPR_N PF18391.1 KFP13188.1 - 2.9 8.7 6.6 4.6 8.1 2.0 3.0 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Calcyon PF06387.11 KFP13189.1 - 5.5e-88 293.7 0.1 6.3e-88 293.5 0.1 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) MgsA_C PF12002.8 KFP13189.1 - 0.05 13.5 0.3 0.088 12.7 0.3 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF2448 PF10476.9 KFP13189.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) zf-LITAF-like PF10601.9 KFP13189.1 - 0.3 11.4 1.4 0.35 11.2 0.2 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.6 KFP13191.1 - 1.4e-44 148.6 49.4 7.3e-09 35.7 3.8 8.4 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP13191.1 - 1.3e-32 110.4 50.7 5.4e-06 26.6 1.1 8.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type BTB PF00651.31 KFP13191.1 - 2e-25 89.2 0.8 4.3e-25 88.1 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP13191.1 - 8.6e-24 82.2 46.8 0.00085 20.0 0.9 8.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP13191.1 - 1.9e-12 46.9 51.5 6.8e-05 22.8 0.3 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP13191.1 - 1.8e-11 44.0 37.0 0.0032 17.7 0.7 8.4 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP13191.1 - 5.1e-08 33.0 45.0 0.0052 17.1 0.6 8.8 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFP13191.1 - 3.2e-06 26.6 25.2 1 9.0 0.1 7.5 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFP13191.1 - 0.00071 19.3 16.8 0.16 11.8 0.1 5.5 2 2 4 6 6 6 3 GAGA factor Zn-ribbon_8 PF09723.10 KFP13191.1 - 0.00083 19.4 24.4 0.51 10.5 1.8 5.3 3 2 0 4 4 4 3 Zinc ribbon domain ADK_lid PF05191.14 KFP13191.1 - 0.033 14.2 16.5 7.5 6.6 0.0 5.2 3 1 1 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_3rep PF18868.1 KFP13191.1 - 0.091 13.4 23.0 0.31 11.7 0.4 6.0 2 1 2 5 5 4 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 KFP13191.1 - 0.1 12.8 37.0 0.091 12.9 11.9 5.4 1 1 3 4 4 4 0 FYVE zinc finger zf-MYST PF17772.1 KFP13191.1 - 0.11 12.1 15.3 23 4.7 0.1 5.7 5 1 0 5 5 5 0 MYST family zinc finger domain zf-RING_7 PF02591.15 KFP13191.1 - 0.9 9.8 0.0 0.9 9.8 0.0 5.1 6 1 0 6 6 6 0 C4-type zinc ribbon domain CpXC PF14353.6 KFP13191.1 - 1.7 8.7 10.9 4.2 7.4 0.1 4.5 5 0 0 5 5 5 0 CpXC protein DUF3268 PF11672.8 KFP13191.1 - 3.2 8.1 18.3 3.4 8.0 0.4 4.4 2 2 1 4 4 4 0 zinc-finger-containing domain zf-C2HC_2 PF13913.6 KFP13191.1 - 3.7 7.5 37.0 0.47 10.4 0.5 7.4 8 0 0 8 8 8 0 zinc-finger of a C2HC-type Otopetrin PF03189.13 KFP13193.1 - 2.1e-48 165.3 23.0 2.7e-20 72.6 8.1 3.8 2 1 0 3 3 3 3 Otopetrin FixQ PF05545.11 KFP13193.1 - 1.4 9.0 3.7 45 4.1 0.1 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ 7tm_1 PF00001.21 KFP13194.1 - 1.7e-74 250.5 16.0 2.1e-74 250.2 16.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP13194.1 - 1.3e-12 47.6 12.7 1.7e-11 44.0 12.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP13194.1 - 2.5e-06 27.3 19.7 3e-06 27.1 12.8 2.7 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-LITAF-like PF10601.9 KFP13194.1 - 7.5 6.9 11.2 0.47 10.8 2.7 3.0 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Sugar_tr PF00083.24 KFP13195.1 - 5.7e-110 368.3 25.0 6.9e-110 368.0 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP13195.1 - 1.8e-31 109.3 45.8 7.4e-24 84.3 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec63 PF02889.16 KFP13196.1 - 6.7e-70 235.2 0.3 2.9e-69 233.1 0.3 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KFP13196.1 - 2.1e-52 177.5 0.1 1e-24 87.3 0.0 3.0 3 0 0 3 3 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KFP13196.1 - 9.3e-38 128.8 1.0 2.8e-37 127.3 1.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KFP13196.1 - 6.7e-26 91.3 0.0 1.2e-11 45.0 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP13196.1 - 1.7e-08 34.7 0.0 9.7e-07 29.1 0.0 3.8 3 2 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFP13196.1 - 2.2e-08 34.0 0.0 0.0043 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFP13196.1 - 1.7e-07 31.6 0.0 0.017 15.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KFP13196.1 - 0.00013 21.5 0.0 0.081 12.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein T2SSE PF00437.20 KFP13196.1 - 0.00032 19.9 0.0 1 8.4 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 KFP13196.1 - 0.0049 16.6 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_16 PF13191.6 KFP13196.1 - 0.011 16.1 0.0 4.4 7.7 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain UvrD-helicase PF00580.21 KFP13196.1 - 0.029 13.9 0.0 7.2 6.0 0.0 2.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Sigma54_activ_2 PF14532.6 KFP13196.1 - 0.038 14.1 0.1 2 8.5 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFP13196.1 - 0.066 12.7 0.0 6.8 6.2 0.0 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP13196.1 - 0.067 12.9 0.2 2.1 8.1 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 KFP13196.1 - 0.12 12.2 1.4 2.9 7.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain Sec63 PF02889.16 KFP13197.1 - 1.2e-24 86.8 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF603 PF04645.12 KFP13197.1 - 0.00025 20.8 0.1 0.00029 20.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF603 Peptidase_C39 PF03412.15 KFP13197.1 - 0.044 13.6 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase C39 family TFX_C PF14601.6 KFP13197.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 DNA_binding protein, TFX, C-term DUF975 PF06161.11 KFP13198.1 - 0.11 12.2 0.2 0.15 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) START PF01852.19 KFP13199.1 - 1.3e-18 67.2 0.3 1.8e-18 66.7 0.3 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 KFP13199.1 - 0.098 12.6 0.9 0.25 11.3 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) EMP24_GP25L PF01105.24 KFP13200.1 - 9e-17 61.6 0.0 9.7e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoLip_ATPase_C PF16212.5 KFP13201.1 - 1.3e-77 260.9 37.5 1.3e-77 260.9 37.5 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP13201.1 - 1.7e-22 78.9 1.8 9.5e-22 76.5 1.8 2.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP13201.1 - 4.1e-13 50.1 0.9 1.7e-07 31.7 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP13201.1 - 2.6e-10 40.2 0.0 2e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP13201.1 - 1.9e-09 37.3 0.4 1.9e-09 37.3 0.4 3.1 2 2 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP13201.1 - 0.00019 21.2 0.0 0.0073 16.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase U3_assoc_6 PF08640.11 KFP13201.1 - 0.039 14.0 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 HAD PF12710.7 KFP13201.1 - 0.11 12.9 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cullin_binding PF03556.15 KFP13202.1 - 1.4e-37 128.8 0.9 1.4e-37 128.8 0.9 2.1 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFP13202.1 - 1.1e-09 38.0 3.0 1.3e-09 37.7 0.1 2.7 3 0 0 3 3 3 1 UBA-like domain TAP_C PF03943.13 KFP13202.1 - 0.0026 17.3 0.5 0.024 14.3 0.2 2.7 3 0 0 3 3 3 1 TAP C-terminal domain CPSase_L_D2 PF02786.17 KFP13203.1 - 5.1e-78 261.4 0.2 9.3e-78 260.5 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFP13203.1 - 3.8e-48 162.6 1.6 8.6e-47 158.3 0.2 2.9 3 0 0 3 3 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFP13203.1 - 7.3e-36 122.6 0.0 4.1e-35 120.1 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFP13203.1 - 5.9e-15 54.9 0.3 2.5e-14 52.9 0.3 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFP13203.1 - 4.5e-14 52.5 0.1 1.1e-13 51.1 0.1 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFP13203.1 - 2.1e-10 40.5 0.2 4.6e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFP13203.1 - 4.1e-06 26.5 0.0 1.3e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFP13203.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KFP13203.1 - 0.00015 22.4 0.2 0.42 11.3 0.0 3.0 3 0 0 3 3 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KFP13203.1 - 0.00035 20.3 3.4 0.0085 15.9 0.0 3.0 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KFP13203.1 - 0.00085 18.6 0.1 0.95 8.6 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 KFP13203.1 - 0.0021 17.8 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KFP13203.1 - 0.0023 17.3 0.2 0.36 10.0 0.0 2.8 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KFP13203.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 KFP13203.1 - 0.097 12.6 0.6 0.28 11.1 0.2 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Lamp PF01299.17 KFP13204.1 - 3.2e-19 69.2 0.0 3.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) EBP50_C PF09007.11 KFP13205.1 - 0.34 11.9 9.2 0.069 14.2 5.3 1.9 1 1 0 2 2 2 0 EBP50, C-terminal RhoGEF PF00621.20 KFP13206.1 - 8.9e-36 123.8 4.5 8.9e-36 123.8 4.5 2.6 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFP13206.1 - 5.9e-09 36.4 2.5 6.9e-09 36.2 1.1 1.9 2 0 0 2 2 2 1 PH domain CRAL_TRIO_2 PF13716.6 KFP13206.1 - 1.8e-06 28.1 0.0 4.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFP13206.1 - 1.2e-05 25.8 18.4 2.5e-05 24.7 0.6 4.7 3 1 2 5 5 5 2 Spectrin repeat PH_10 PF15411.6 KFP13206.1 - 6.9e-05 23.1 0.5 6.9e-05 23.1 0.5 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain CRAL_TRIO PF00650.20 KFP13206.1 - 0.086 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO domain Goodbye PF17109.5 KFP13206.1 - 0.31 11.5 2.7 1.7 9.1 0.1 3.5 4 0 0 4 4 4 0 fungal STAND N-terminal Goodbye domain Galactosyl_T PF01762.21 KFP13207.1 - 1e-46 159.2 0.0 1.5e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KFP13207.1 - 0.00031 20.3 0.0 0.0007 19.1 0.0 1.7 1 1 0 1 1 1 1 Fringe-like DUF3271 PF11675.8 KFP13207.1 - 0.15 11.3 1.3 0.22 10.7 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3271) Rep_fac_C PF08542.11 KFP13208.1 - 4.4e-20 71.9 0.3 9.1e-20 70.9 0.3 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFP13208.1 - 1.1e-17 64.6 0.0 4.1e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFP13208.1 - 3.1e-12 46.6 0.0 2.7e-10 40.3 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KFP13208.1 - 5e-06 26.8 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KFP13208.1 - 5.5e-06 26.9 0.0 0.0032 17.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KFP13208.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KFP13208.1 - 2e-05 24.4 0.0 5.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP13208.1 - 8.6e-05 22.5 0.2 0.00032 20.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP13208.1 - 0.0001 22.6 0.0 0.0063 16.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFP13208.1 - 0.00019 20.7 0.0 0.00039 19.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFP13208.1 - 0.00053 19.8 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KFP13208.1 - 0.0012 18.6 0.1 0.0029 17.4 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KFP13208.1 - 0.0014 18.0 0.0 0.047 13.1 0.0 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFP13208.1 - 0.0023 18.3 0.1 0.014 15.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP13208.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFP13208.1 - 0.019 15.0 0.0 0.11 12.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KFP13208.1 - 0.021 14.6 0.1 0.74 9.5 0.1 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49_C PF17856.1 KFP13208.1 - 0.021 14.9 0.1 0.065 13.4 0.1 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_23 PF13476.6 KFP13208.1 - 0.034 14.7 0.0 0.084 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP13208.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFP13208.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFP13208.1 - 0.078 13.0 0.0 0.53 10.3 0.0 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KFP13208.1 - 0.083 12.3 0.0 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 KFP13208.1 - 0.083 12.6 0.2 1.7 8.4 0.0 2.6 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KFP13208.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 KFP13209.1 - 9.5e-44 149.2 0.3 1.7e-43 148.4 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP13209.1 - 2.6e-32 111.5 0.5 8.5e-31 106.6 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP13209.1 - 1.6e-07 31.5 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFP13209.1 - 5.5e-05 23.5 0.3 0.00021 21.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP13209.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFP13209.1 - 0.071 13.1 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KFP13209.1 - 0.072 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 KFP13209.1 - 0.081 12.2 0.1 0.25 10.6 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 KFP13209.1 - 0.1 12.8 0.4 1.2 9.5 0.4 2.4 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFP13209.1 - 0.14 11.6 0.2 0.24 10.9 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Fanconi_A PF03511.14 KFP13209.1 - 0.16 11.9 0.0 27 4.8 0.0 2.4 2 0 0 2 2 2 0 Fanconi anaemia group A protein LRR_8 PF13855.6 KFP13210.1 - 3.9e-37 125.8 29.1 4.2e-14 52.1 12.2 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP13210.1 - 1.8e-17 63.2 17.3 8.7e-06 26.0 0.1 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP13210.1 - 1.7e-15 56.8 0.0 3.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.6 KFP13210.1 - 2.7e-15 56.5 0.1 1e-14 54.6 0.1 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KFP13210.1 - 2.1e-13 50.6 0.0 5.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP13210.1 - 9e-10 38.6 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP13210.1 - 1.1e-09 37.5 8.5 0.95 10.3 0.0 6.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP13210.1 - 6.6e-09 35.5 5.7 5.6e-05 22.7 3.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Ig_2 PF13895.6 KFP13210.1 - 8.7e-07 29.2 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP13210.1 - 0.00047 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain C2-set_2 PF08205.12 KFP13210.1 - 0.0095 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain LSR PF05624.14 KFP13210.1 - 0.019 15.0 1.5 0.019 15.0 1.5 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFP13210.1 - 0.025 14.7 0.0 6.5 7.0 0.0 2.5 1 1 1 2 2 2 0 Immunoglobulin V-set domain DUF240 PF03086.14 KFP13210.1 - 0.12 12.3 4.6 0.2 11.6 3.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF240) Cast PF10174.9 KFP13211.1 - 0.00021 19.7 9.7 0.00024 19.5 9.7 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone KASH_CCD PF14662.6 KFP13211.1 - 0.00022 21.1 14.9 0.0003 20.7 14.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KFP13211.1 - 0.00049 20.1 16.2 0.0045 17.0 0.5 3.5 2 1 1 3 3 3 2 bZIP transcription factor DUF4200 PF13863.6 KFP13211.1 - 0.0019 18.6 18.1 0.02 15.3 18.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) HAUS-augmin3 PF14932.6 KFP13211.1 - 0.0027 17.4 8.1 0.0037 16.9 8.1 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Fmp27_WPPW PF10359.9 KFP13211.1 - 0.0087 15.0 7.9 0.0099 14.8 7.9 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain MPS2 PF17060.5 KFP13211.1 - 0.012 14.9 7.5 0.014 14.7 7.5 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4686 PF15742.5 KFP13211.1 - 0.015 14.5 16.7 0.021 14.0 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Exonuc_VII_L PF02601.15 KFP13211.1 - 0.026 14.1 6.9 0.03 13.9 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 KFP13211.1 - 0.03 12.3 1.8 0.032 12.2 1.8 1.1 1 0 0 1 1 1 0 Prominin DUF2937 PF11157.8 KFP13211.1 - 0.03 14.0 4.3 0.051 13.3 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) SlyX PF04102.12 KFP13211.1 - 0.034 14.8 6.3 0.034 14.8 6.3 3.2 1 1 1 3 3 3 0 SlyX CALCOCO1 PF07888.11 KFP13211.1 - 0.039 12.8 17.0 0.05 12.5 17.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like VirC1 PF07015.11 KFP13211.1 - 0.039 13.3 0.5 0.05 12.9 0.5 1.1 1 0 0 1 1 1 0 VirC1 protein LCD1 PF09798.9 KFP13211.1 - 0.047 12.2 5.2 0.067 11.7 5.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Jnk-SapK_ap_N PF09744.9 KFP13211.1 - 0.05 13.8 17.7 1.6 9.0 3.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SpoIISA_toxin PF14171.6 KFP13211.1 - 0.05 13.3 0.7 0.062 13.0 0.7 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Aminopep PF10023.9 KFP13211.1 - 0.059 12.7 2.4 0.073 12.4 2.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase FapA PF03961.13 KFP13211.1 - 0.064 11.9 6.8 0.081 11.5 6.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KFP13211.1 - 0.064 12.1 15.3 0.083 11.8 15.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFP13211.1 - 0.077 12.3 4.4 0.089 12.1 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 KFP13211.1 - 0.1 12.7 0.9 0.1 12.7 0.9 3.6 3 2 0 3 3 3 0 Basic region leucine zipper DUF4988 PF16378.5 KFP13211.1 - 0.1 12.2 3.4 3.9 7.1 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function DNA_primase_lrg PF04104.14 KFP13211.1 - 0.11 11.8 2.1 0.13 11.6 2.1 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DHR10 PF18595.1 KFP13211.1 - 0.16 12.1 20.3 0.28 11.2 15.9 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF737 PF05300.11 KFP13211.1 - 0.21 11.9 14.5 0.29 11.4 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ADIP PF11559.8 KFP13211.1 - 0.23 11.5 15.0 1.1 9.3 11.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KFP13211.1 - 0.24 11.6 16.7 0.21 11.8 14.6 1.7 1 1 0 1 1 1 0 Tropomyosin like HMMR_N PF15905.5 KFP13211.1 - 0.31 10.5 15.2 0.36 10.3 15.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CREPT PF16566.5 KFP13211.1 - 0.32 11.1 10.7 0.46 10.6 10.7 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour UPF0515 PF15135.6 KFP13211.1 - 0.4 10.0 2.7 0.48 9.7 2.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 CLZ PF16526.5 KFP13211.1 - 0.42 11.0 18.1 4.4 7.7 11.2 3.1 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KFP13211.1 - 0.44 10.6 9.2 1.4 9.0 9.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KFP13211.1 - 0.45 10.6 11.1 0.32 11.1 8.5 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 KFP13211.1 - 0.52 10.3 19.1 0.82 9.7 9.2 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 KFP13211.1 - 0.56 8.1 8.2 0.67 7.8 8.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 KFP13211.1 - 0.6 10.3 9.7 0.6 10.3 7.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KFP13211.1 - 0.75 9.6 12.9 1.2 9.0 12.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 KFP13211.1 - 0.98 8.4 14.0 1.4 7.9 14.0 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 KFP13211.1 - 1.1 9.8 10.4 1.5 9.4 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Hemerythrin PF01814.23 KFP13211.1 - 1.1 9.9 10.8 3.9 8.1 1.1 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain AKNA PF12443.8 KFP13211.1 - 1.2 9.8 7.6 1.2 9.8 4.8 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor Sec2p PF06428.11 KFP13211.1 - 1.2 9.1 15.0 0.23 11.4 3.7 3.2 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Occludin_ELL PF07303.13 KFP13211.1 - 1.3 9.7 7.0 1.1 10.0 5.2 1.8 1 1 1 2 2 2 0 Occludin homology domain DUF4618 PF15397.6 KFP13211.1 - 1.4 8.3 15.7 2.3 7.5 15.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) GrpE PF01025.19 KFP13211.1 - 1.4 8.6 13.1 2.8 7.6 5.1 2.6 1 1 2 3 3 3 0 GrpE FAM76 PF16046.5 KFP13211.1 - 1.5 8.1 12.4 3.3 7.0 12.4 1.6 1 1 0 1 1 1 0 FAM76 protein ATG16 PF08614.11 KFP13211.1 - 1.6 8.9 18.4 0.73 10.0 10.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CCDC-167 PF15188.6 KFP13211.1 - 1.6 9.1 17.5 0.9 9.9 3.5 3.0 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF1192 PF06698.11 KFP13211.1 - 1.7 8.8 13.8 5.1 7.2 0.4 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF1192) DUF445 PF04286.12 KFP13211.1 - 1.7 8.4 10.0 2 8.2 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF848 PF05852.11 KFP13211.1 - 1.8 8.7 11.7 0.29 11.2 3.6 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4795 PF16043.5 KFP13211.1 - 1.9 8.1 16.4 9.3 5.8 16.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) UPF0242 PF06785.11 KFP13211.1 - 2.1 8.4 15.6 2.9 7.9 15.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CorA PF01544.18 KFP13211.1 - 2.2 7.5 7.3 2.8 7.2 7.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 KFP13211.1 - 2.3 8.2 16.5 2.3 8.2 3.9 3.0 1 1 2 3 3 3 0 Prefoldin subunit YabA PF06156.13 KFP13211.1 - 2.6 8.8 13.7 0.63 10.7 3.9 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF641 PF04859.12 KFP13211.1 - 4.5 7.6 13.4 12 6.2 7.9 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) kleA_kleC PF17383.2 KFP13211.1 - 4.8 7.6 7.7 1.7 9.0 2.1 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A CENP-H PF05837.12 KFP13211.1 - 5.2 7.5 16.5 15 6.0 10.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 KFP13211.1 - 5.9 6.1 14.2 4.6 6.5 10.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 KFP13211.1 - 6.5 5.5 4.6 7.3 5.4 4.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Lzipper-MIP1 PF14389.6 KFP13211.1 - 6.7 7.1 18.2 0.93 9.8 10.8 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Spc29 PF17082.5 KFP13211.1 - 8.7 6.1 11.9 2.5 7.9 7.4 1.9 1 1 1 2 2 2 0 Spindle Pole Component 29 FUSC PF04632.12 KFP13211.1 - 8.7 4.7 5.3 10 4.5 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PX PF00787.24 KFP13212.1 - 2.1e-19 69.6 0.1 4.7e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 PX domain RA PF00788.23 KFP13212.1 - 6e-12 46.0 0.1 2.1e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain USP7_C2 PF14533.6 KFP13212.1 - 0.00061 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal SNX17_FERM_C PF18116.1 KFP13212.1 - 0.0031 17.6 0.1 0.011 15.8 0.1 2.0 1 0 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain PDZ_6 PF17820.1 KFP13212.1 - 0.013 15.4 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 PDZ domain USP8_interact PF08941.10 KFP13214.1 - 2.1e-14 53.7 4.4 3.6e-14 53.0 4.4 1.4 1 0 0 1 1 1 1 USP8 interacting Sina PF03145.16 KFP13214.1 - 3.5e-06 27.1 2.5 4.8e-06 26.7 2.5 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-rbx1 PF12678.7 KFP13214.1 - 4.2e-06 27.0 5.4 4.2e-06 27.0 5.4 2.6 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP13214.1 - 2.6e-05 24.0 3.7 2.6e-05 24.0 3.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP13214.1 - 2.7e-05 24.4 4.6 2.7e-05 24.4 4.6 2.4 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP13214.1 - 0.00012 21.8 5.6 0.00012 21.8 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KFP13214.1 - 0.00023 21.8 3.7 0.036 14.8 2.0 2.7 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 KFP13214.1 - 0.00027 20.8 1.4 0.00027 20.8 1.4 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Trimer_CC PF08954.11 KFP13214.1 - 0.00081 18.9 0.4 0.0037 16.8 0.2 2.1 2 0 0 2 2 2 1 Trimerisation motif zf-RING_5 PF14634.6 KFP13214.1 - 0.0013 18.7 3.6 0.0013 18.7 3.6 2.2 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP13214.1 - 0.0057 16.5 2.1 0.017 15.0 2.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP13214.1 - 0.0063 16.5 2.2 0.016 15.2 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger BLOC1_2 PF10046.9 KFP13214.1 - 0.018 15.4 3.1 0.038 14.3 3.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.12 KFP13214.1 - 0.019 15.3 0.6 0.033 14.5 0.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-RING_UBOX PF13445.6 KFP13214.1 - 0.021 14.9 4.7 0.021 14.9 4.7 2.2 3 0 0 3 3 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 KFP13214.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.0 2 1 1 3 3 2 0 zf-RING of BARD1-type protein Atx10homo_assoc PF09759.9 KFP13214.1 - 0.045 13.8 2.0 0.61 10.1 0.4 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain zf-C3HC4_4 PF15227.6 KFP13214.1 - 0.047 13.8 3.4 0.047 13.8 3.4 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-CCCH_6 PF18585.1 KFP13214.1 - 0.082 12.8 2.5 0.17 11.8 0.1 2.6 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 SlyX PF04102.12 KFP13214.1 - 0.083 13.5 5.5 0.25 12.0 5.4 1.9 1 1 0 1 1 1 0 SlyX zf-TRAF_2 PF15965.5 KFP13214.1 - 0.087 13.3 11.7 0.11 13.0 7.9 2.4 1 1 1 2 2 2 0 TRAF-like zinc-finger DUF1754 PF08555.10 KFP13214.1 - 0.12 13.2 0.3 0.16 12.8 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Zn_ribbon_17 PF17120.5 KFP13214.1 - 0.5 10.0 12.9 0.089 12.4 4.0 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Swi5 PF07061.11 KFP13214.1 - 1.4 9.1 8.2 0.18 11.9 3.3 1.9 2 0 0 2 2 2 0 Swi5 zinc_ribbon_16 PF17034.5 KFP13214.1 - 1.9 8.7 9.0 2.4 8.4 2.8 2.2 2 0 0 2 2 2 0 Zinc-ribbon like family AD PF09793.9 KFP13215.1 - 1.8e-25 88.9 0.6 2.2e-25 88.6 0.6 1.1 1 0 0 1 1 1 1 Anticodon-binding domain FYRC PF05965.14 KFP13216.1 - 1.4e-20 73.2 0.0 2.8e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KFP13216.1 - 1.7e-20 72.6 0.1 4.2e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H_2 PF13832.6 KFP13216.1 - 1.2e-08 35.0 5.3 1.2e-08 35.0 5.3 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP13216.1 - 4.4e-08 33.3 7.0 4.4e-08 33.3 7.0 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain SET PF00856.28 KFP13216.1 - 0.029 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 SET domain 7tm_4 PF13853.6 KFP13217.1 - 2.6e-46 158.6 8.8 3e-46 158.4 8.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP13217.1 - 7e-26 91.1 12.4 9.2e-26 90.7 12.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 KFP13224.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BACK PF07707.15 KFP13225.1 - 2.6e-33 114.2 0.7 7.3e-33 112.8 0.2 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP13225.1 - 8.9e-29 100.0 1.9 1.3e-28 99.4 0.4 2.0 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_M10 PF00413.24 KFP13227.1 - 1.6e-60 203.5 0.0 2.6e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP13227.1 - 1.5e-55 184.9 16.4 1.4e-16 60.1 0.6 4.6 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.8 KFP13227.1 - 4.3e-32 109.9 0.3 7.7e-32 109.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.18 KFP13227.1 - 1e-09 38.4 0.1 3.9e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP13227.1 - 9.4e-05 22.1 0.9 0.33 10.6 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 KFP13227.1 - 0.036 13.0 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 KFP13227.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.8 KFP13227.1 - 0.066 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 KFP13227.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP13227.1 - 0.27 11.4 0.2 0.67 10.1 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Copine PF07002.16 KFP13228.1 - 1.2e-91 306.0 0.0 1.7e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP13228.1 - 6.4e-29 100.3 0.2 5.1e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP13228.1 - 1.8e-05 24.9 0.0 7.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus DUF3211 PF11485.8 KFP13228.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) TPR_17 PF13431.6 KFP13229.1 - 1.4e-07 31.4 1.3 0.26 11.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP13229.1 - 8.7e-07 28.5 10.7 0.18 11.7 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP13229.1 - 8.3e-06 26.2 0.2 0.2 12.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP13229.1 - 1.7e-05 25.2 2.6 16 6.6 0.0 4.8 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP13229.1 - 2.9e-05 23.8 14.5 0.82 9.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP13229.1 - 0.0061 16.2 0.1 0.94 9.2 0.0 3.7 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 KFP13229.1 - 0.1 12.9 8.1 1.4 9.3 0.4 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP13229.1 - 0.23 11.7 6.6 0.87 9.9 0.6 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HECT PF00632.25 KFP13230.1 - 1.6e-97 326.7 0.5 2.3e-97 326.2 0.5 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP13230.1 - 2.9e-50 168.0 31.0 2.1e-13 50.1 1.5 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFP13230.1 - 7e-12 45.6 0.1 2.2e-11 43.9 0.1 1.9 1 0 0 1 1 1 1 C2 domain Carb_anhydrase PF00194.21 KFP13231.1 - 1.5e-92 309.8 0.0 1.6e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFP13232.1 - 5.3e-84 281.7 0.0 5.9e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KFP13233.1 - 1.7e-86 289.9 0.0 1.9e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.21 KFP13234.1 - 1e-62 211.9 16.3 1.4e-62 211.4 16.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP13234.1 - 5.6e-29 99.9 0.5 1.4e-28 98.6 0.5 1.8 1 0 0 1 1 1 1 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFP13234.1 - 5.8e-10 39.4 10.1 5.8e-10 39.4 10.1 1.8 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP13234.1 - 9.5e-09 35.0 22.8 6.4e-08 32.3 22.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Brr6_like_C_C PF10104.9 KFP13234.1 - 7.2 6.4 10.5 0.34 10.7 1.8 3.0 2 2 1 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain RabGAP-TBC PF00566.18 KFP13235.1 - 6e-15 55.5 6.8 1.4e-12 47.8 2.5 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SOAR PF16533.5 KFP13236.1 - 1.2e-40 137.5 3.9 1.2e-40 137.5 3.9 3.0 2 1 1 3 3 3 1 STIM1 Orai1-activating region SAM_2 PF07647.17 KFP13236.1 - 3e-12 46.5 0.1 8.3e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP13236.1 - 3.9e-07 30.4 0.1 1.2e-06 28.8 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4446 PF14584.6 KFP13236.1 - 0.39 10.7 4.9 0.089 12.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) ESSS PF10183.9 KFP13236.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.0 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Orbi_NS3 PF01616.16 KFP13236.1 - 1.1 9.0 3.3 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Orbivirus NS3 L27 PF02828.16 KFP13237.1 - 5.5e-23 80.5 0.3 1.3e-22 79.3 0.2 1.7 2 0 0 2 2 2 1 L27 domain PDZ PF00595.24 KFP13237.1 - 4.7e-21 74.9 0.6 6.9e-21 74.4 0.6 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP13237.1 - 1.3e-13 50.6 0.6 2.6e-13 49.6 0.2 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP13237.1 - 0.0044 17.3 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain His_Phos_2 PF00328.22 KFP13237.1 - 0.084 12.2 0.0 0.091 12.1 0.0 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) NGF PF00243.18 KFP13238.1 - 1.7e-46 157.1 2.4 2.2e-46 156.7 2.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.5 KFP13238.1 - 7.6e-05 23.2 0.9 0.00011 22.7 0.9 1.2 1 0 0 1 1 1 1 Spaetzle Kinesin PF00225.23 KFP13239.1 - 8.8e-115 383.2 0.5 8.8e-115 383.2 0.5 2.9 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP13239.1 - 3.3e-25 88.8 0.1 1.2e-24 87.0 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding DUF2443 PF10398.9 KFP13239.1 - 4.5 7.4 6.9 4.5 7.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) Methyltransf_5 PF01795.19 KFP13240.1 - 4.9e-81 272.6 0.1 3.6e-80 269.8 0.1 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltr_RsmB-F PF01189.17 KFP13240.1 - 0.0017 18.0 0.0 0.0041 16.8 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 KFP13240.1 - 0.0037 17.9 0.0 0.027 15.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP13240.1 - 0.0051 16.6 0.0 3.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFP13240.1 - 0.017 15.8 0.0 0.76 10.5 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 KFP13240.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KFP13240.1 - 0.069 13.9 0.0 2 9.2 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain MTS PF05175.14 KFP13240.1 - 0.15 11.6 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Cys_knot PF00007.22 KFP13241.1 - 7e-31 106.6 17.3 8.4e-31 106.4 17.3 1.1 1 0 0 1 1 1 1 Cystine-knot domain ARF7EP_C PF14949.6 KFP13242.1 - 1.4e-36 125.3 6.7 1.5e-36 125.2 5.4 1.7 2 0 0 2 2 2 1 ARF7 effector protein C-terminus Transposon_TraM PF12508.8 KFP13242.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Conjugative transposon, TraM Metallophos PF00149.28 KFP13243.1 - 2e-11 44.8 0.8 3e-11 44.2 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP13243.1 - 0.00042 20.5 0.0 0.17 12.1 0.0 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.31 KFP13245.1 - 2e-17 63.0 0.4 2.8e-17 62.6 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KFP13245.1 - 1.4e-11 44.0 8.9 2.5e-11 43.1 8.9 1.5 1 0 0 1 1 1 1 CSL zinc finger Peptidase_S24 PF00717.23 KFP13246.1 - 7.2e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFP13246.1 - 1.7e-07 31.1 0.0 0.00059 19.6 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 PAXNEB PF05625.11 KFP13247.1 - 1.5e-92 310.7 0.0 1.6e-92 310.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein PAX PF00292.18 KFP13248.1 - 1.3e-41 141.5 0.2 2.8e-41 140.3 0.2 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFP13248.1 - 6.5e-23 80.4 4.5 1.2e-22 79.5 4.5 1.5 1 0 0 1 1 1 1 Homeodomain HTH_32 PF13565.6 KFP13248.1 - 0.016 15.8 1.9 0.075 13.7 0.0 2.5 2 1 0 2 2 2 0 Homeodomain-like domain Homeobox_KN PF05920.11 KFP13248.1 - 0.13 12.1 1.1 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain EF-hand_1 PF00036.32 KFP13249.1 - 1.3e-17 61.9 18.1 0.00064 19.1 0.1 6.8 6 1 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 KFP13249.1 - 1.7e-16 58.7 14.0 0.00069 19.4 0.1 6.4 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 KFP13249.1 - 1.2e-15 57.7 16.5 2.1e-07 31.3 0.4 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP13249.1 - 5e-09 35.3 24.8 0.024 14.1 0.4 6.7 6 1 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 KFP13249.1 - 5.3e-06 26.2 16.9 0.21 11.5 0.3 6.1 6 2 2 8 8 8 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP13249.1 - 0.0033 17.7 11.2 0.53 10.6 0.2 3.5 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Homez PF11569.8 KFP13249.1 - 0.45 10.0 3.0 4.9 6.7 0.2 3.0 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez EF-hand_4 PF12763.7 KFP13249.1 - 8.2 6.4 12.9 3.9 7.5 0.3 4.4 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand Lipase PF00151.19 KFP13250.1 - 3.2e-120 401.5 0.0 3.9e-120 401.2 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFP13250.1 - 1.1e-18 67.9 1.2 2e-18 67.0 1.2 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFP13250.1 - 0.00048 20.8 0.2 0.0007 20.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP13250.1 - 0.0051 16.5 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sec7 PF01369.20 KFP13251.1 - 4.1e-44 150.4 0.2 6.7e-44 149.8 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFP13251.1 - 1e-40 138.8 1.8 4.9e-40 136.6 0.7 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFP13251.1 - 7.8e-15 55.3 0.2 2.2e-14 53.8 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP13251.1 - 0.0064 16.9 2.5 0.0088 16.4 0.7 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KFP13251.1 - 0.011 16.0 0.3 0.025 15.0 0.3 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region RVT_1 PF00078.27 KFP13253.1 - 2.4e-31 109.0 0.0 3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP13253.1 - 2.9e-16 59.1 0.3 6.4e-16 57.9 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain NIPSNAP PF07978.13 KFP13254.1 - 3.1e-53 178.3 0.5 2.6e-30 104.6 0.1 2.0 2 0 0 2 2 2 2 NIPSNAP Choline_transpo PF04515.12 KFP13255.1 - 8.9e-103 343.9 37.7 8.9e-103 343.9 37.7 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter SPRY PF00622.28 KFP13256.1 - 1.4e-13 51.0 0.8 2.5e-13 50.2 0.2 1.8 2 0 0 2 2 2 1 SPRY domain fn3 PF00041.21 KFP13256.1 - 2.9e-06 27.5 0.0 1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain Helo_like_N PF17111.5 KFP13256.1 - 0.0072 15.7 0.5 0.015 14.7 0.5 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Spc29 PF17082.5 KFP13256.1 - 0.012 15.5 1.0 0.023 14.5 1.0 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 Fib_alpha PF08702.10 KFP13256.1 - 0.051 13.8 4.8 0.11 12.7 4.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Hrs_helical PF12210.8 KFP13256.1 - 0.056 14.0 1.5 0.12 13.0 1.5 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ntox28 PF15605.6 KFP13256.1 - 0.093 13.0 0.8 0.26 11.6 0.3 2.0 2 0 0 2 2 2 0 Bacterial toxin 28 COS PF18568.1 KFP13256.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain DUF148 PF02520.17 KFP13256.1 - 0.21 11.7 4.4 0.4 10.8 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 NPV_P10 PF05531.12 KFP13256.1 - 0.3 11.6 3.4 10 6.7 3.4 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KFP13256.1 - 0.8 9.7 5.3 2.2 8.3 4.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KFP13256.1 - 1.3 9.4 3.8 3.3 8.2 0.3 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) LicD PF04991.13 KFP13257.1 - 4.5e-06 27.0 0.5 1.9e-05 24.9 0.1 2.3 2 1 1 3 3 3 1 LicD family HLH PF00010.26 KFP13258.1 - 1.3e-17 63.5 0.4 1.7e-17 63.1 0.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 KFP13258.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain PMBR PF09373.10 KFP13258.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat TRIC PF05197.13 KFP13259.1 - 1.3e-83 279.3 4.6 1.5e-83 279.1 4.6 1.1 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 KFP13259.1 - 0.0088 15.9 6.5 0.18 11.7 0.1 2.8 2 1 0 2 2 2 2 UPF0126 domain zf-H2C2_5 PF13909.6 KFP13260.1 - 3.1e-16 58.8 28.3 1.2e-07 31.3 1.8 28.6 30 0 0 30 30 30 16 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFP13260.1 - 2e-09 36.9 156.9 0.0082 15.8 1.4 27.0 26 3 4 30 30 30 15 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KFP13260.1 - 0.0073 16.7 6.6 0.0073 16.7 6.6 29.2 34 0 0 34 34 34 11 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP13260.1 - 0.012 16.4 0.2 0.012 16.4 0.2 34.6 35 0 0 35 35 35 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP13260.1 - 0.054 14.0 0.1 0.054 14.0 0.1 32.5 35 0 0 35 35 35 0 Zinc finger, C2H2 type FOP_dimer PF09398.10 KFP13261.1 - 0.011 16.0 0.0 0.079 13.2 0.0 2.5 2 0 0 2 2 2 0 FOP N terminal dimerisation domain CENP-B_dimeris PF09026.10 KFP13261.1 - 0.014 15.8 6.1 0.017 15.5 4.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RPN2_C PF18004.1 KFP13262.1 - 1.6e-49 167.9 10.9 3.8e-49 166.7 10.9 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFP13262.1 - 1.3e-42 142.1 19.5 5e-09 36.1 0.0 7.9 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFP13262.1 - 2.4e-21 75.9 0.4 1.3e-14 54.4 0.0 5.5 4 1 1 6 6 6 2 HEAT repeats RPN1_RPN2_N PF17781.1 KFP13262.1 - 1.5e-08 34.5 0.2 4.1e-08 33.0 0.2 1.8 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain HEAT PF02985.22 KFP13262.1 - 7.3e-06 25.8 1.0 1.3 9.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFP13262.1 - 0.00047 20.6 1.5 0.52 10.9 0.0 5.0 5 1 2 7 7 6 2 HEAT-like repeat HEAT_PBS PF03130.16 KFP13262.1 - 0.0018 18.8 1.6 6.7 7.7 0.0 4.5 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat PA26 PF04636.13 KFP13262.1 - 0.067 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Tim54 PF11711.8 KFP13262.1 - 0.29 9.9 7.7 0.47 9.2 7.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 KFP13262.1 - 0.71 10.2 12.6 3.5 7.9 12.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.8 KFP13262.1 - 4.5 6.1 11.4 10 4.9 11.4 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.10 KFP13262.1 - 4.5 8.2 14.3 11 7.0 14.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) 7tm_1 PF00001.21 KFP13263.1 - 2.5e-65 220.4 13.5 3.5e-65 220.0 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP13263.1 - 1.2e-11 44.5 14.4 4.3e-11 42.7 14.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP13263.1 - 2.2e-07 30.9 8.4 2.4e-07 30.8 4.7 2.2 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP13263.1 - 2e-05 24.4 13.6 2e-05 24.4 13.6 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2385 PF09539.10 KFP13263.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF1385 PF07136.11 KFP13263.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1385) Ribosomal_L35Ae PF01247.18 KFP13264.1 - 1.6e-46 156.4 0.4 1.8e-46 156.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae DUF2080 PF09853.9 KFP13264.1 - 0.024 14.4 0.4 0.1 12.3 0.0 2.2 2 1 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) RimM PF01782.18 KFP13264.1 - 0.081 13.1 0.0 0.97 9.7 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain IQ PF00612.27 KFP13265.1 - 4.2e-05 23.0 0.1 0.0001 21.7 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Baculo_PEP_C PF04513.12 KFP13265.1 - 1.3 9.1 4.9 2.3 8.3 0.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_8 PF13855.6 KFP13266.1 - 4.2e-23 80.9 11.1 2.1e-08 33.8 1.5 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP13266.1 - 2e-17 63.0 19.4 0.00012 22.4 0.1 5.3 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 KFP13266.1 - 6.9e-10 39.1 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_6 PF13516.6 KFP13266.1 - 0.00078 19.3 13.0 0.62 10.3 0.0 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFP13266.1 - 0.0048 17.3 21.9 30 5.7 0.7 8.2 9 0 0 9 9 9 0 Leucine Rich Repeat CAMSAP_CH PF11971.8 KFP13266.1 - 0.02 14.7 0.0 0.065 13.1 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain LRR_9 PF14580.6 KFP13266.1 - 7.3 6.0 7.3 7.3 6.1 2.7 2.7 2 1 2 4 4 4 0 Leucine-rich repeat FYTT PF07078.11 KFP13267.1 - 2.1e-124 414.9 21.3 2.4e-124 414.7 21.3 1.0 1 0 0 1 1 1 1 Forty-two-three protein zf-RING_9 PF13901.6 KFP13268.1 - 2e-70 237.0 14.5 2e-70 237.0 14.5 2.3 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 KFP13268.1 - 4.6e-09 36.3 0.3 1.1e-08 35.1 0.3 1.6 1 0 0 1 1 1 1 RUN domain DNA_photolyase PF00875.18 KFP13269.1 - 2.8e-20 73.0 0.0 5.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 KFP13269.1 - 0.15 11.5 1.3 0.17 11.3 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase NIDO PF06119.14 KFP13270.1 - 1.1e-09 39.1 0.3 2.4e-09 38.0 0.3 1.6 1 0 0 1 1 1 1 Nidogen-like NIDO PF06119.14 KFP13272.1 - 1e-10 42.4 0.3 3.4e-10 40.7 0.2 1.8 2 0 0 2 2 2 1 Nidogen-like Peptidase_M28 PF04389.17 KFP13273.1 - 2.8e-14 53.3 0.0 5.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 KFP13273.1 - 2.2e-09 37.5 0.1 4.4e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KFP13273.1 - 7.1e-08 32.4 0.0 2.5e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 PA domain Solute_trans_a PF03619.16 KFP13274.1 - 2.8e-37 128.7 17.0 3.5e-37 128.4 17.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CTP_transf_like PF01467.26 KFP13275.1 - 5.7e-32 110.9 0.5 1.2e-31 109.9 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF1664 PF07889.12 KFP13275.1 - 0.056 13.5 0.6 0.092 12.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KH_5 PF13184.6 KFP13275.1 - 0.058 13.5 0.5 0.16 12.0 0.5 1.7 1 0 0 1 1 1 0 NusA-like KH domain YtxH PF12732.7 KFP13275.1 - 0.24 11.9 2.5 0.46 11.1 2.5 1.4 1 0 0 1 1 1 0 YtxH-like protein AKNA PF12443.8 KFP13275.1 - 0.39 11.4 2.7 0.54 11.0 0.8 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF3678 PF12435.8 KFP13275.1 - 2.4 7.6 6.2 0.81 9.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Tctex-1 PF03645.13 KFP13276.1 - 3.8e-26 91.3 0.0 4.3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Trans_coact PF16805.5 KFP13276.1 - 0.044 13.9 0.4 0.53 10.4 0.0 2.1 1 1 1 2 2 2 0 Phage late-transcription coactivator V-set PF07686.17 KFP13277.1 - 1.6e-10 41.1 0.0 2.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP13277.1 - 0.0002 21.9 0.0 0.00051 20.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP13277.1 - 0.0034 17.4 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP13277.1 - 0.0048 17.1 0.3 0.013 15.7 0.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP13277.1 - 0.06 13.7 0.8 0.15 12.4 0.8 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Trypsin PF00089.26 KFP13278.1 - 7.5e-57 192.7 0.0 1.1e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFP13278.1 - 2.4e-50 169.5 1.2 5.3e-29 100.8 0.1 2.6 2 0 0 2 2 2 2 CUB domain Sushi PF00084.20 KFP13278.1 - 5e-15 55.8 17.9 4e-09 36.9 0.2 4.8 5 0 0 5 5 5 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 KFP13278.1 - 1e-08 35.3 10.8 5.7e-08 32.9 8.4 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.20 KFP13278.1 - 3.7e-06 26.7 0.2 0.0096 15.7 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain EGF_CA PF07645.15 KFP13278.1 - 2.8e-05 24.2 7.9 2.8e-05 24.2 7.9 2.6 3 0 0 3 3 3 1 Calcium-binding EGF domain Trypsin_2 PF13365.6 KFP13278.1 - 0.00013 22.8 0.1 0.00026 21.9 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.7 KFP13278.1 - 0.00039 20.3 6.5 0.0042 17.0 3.9 3.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like DUF1986 PF09342.11 KFP13278.1 - 0.027 14.9 0.1 0.063 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) HRM PF02793.22 KFP13278.1 - 0.038 14.3 2.2 6.4 7.2 0.2 2.7 2 0 0 2 2 2 0 Hormone receptor domain DUF2244 PF10003.9 KFP13278.1 - 0.21 11.3 0.1 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Somatostatin PF03002.15 KFP13279.1 - 1.1e-12 47.6 8.4 1.5e-12 47.2 8.4 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family BTB PF00651.31 KFP13280.1 - 4.1e-27 94.6 0.3 6.9e-27 93.9 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP13280.1 - 6.3e-23 80.1 53.7 8.3e-07 29.2 0.5 7.1 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP13280.1 - 6.7e-18 64.1 58.3 3.7e-05 23.9 0.3 7.5 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-met PF12874.7 KFP13280.1 - 2.8e-11 43.4 30.9 0.0081 16.5 0.1 7.0 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP13280.1 - 8.6e-11 41.7 56.5 0.012 16.4 1.1 7.6 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP13280.1 - 2.6e-05 24.4 19.9 0.41 11.0 2.0 6.3 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFP13280.1 - 0.021 14.6 0.9 0.021 14.6 0.9 7.3 6 2 0 6 6 6 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFP13280.1 - 0.032 14.3 1.3 0.032 14.3 1.3 5.7 4 3 3 7 7 7 0 Zinc ribbon domain DUF3342 PF11822.8 KFP13280.1 - 0.033 14.4 0.4 0.074 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) zf-C2H2_6 PF13912.6 KFP13280.1 - 0.039 14.0 0.1 0.039 14.0 0.1 6.5 7 0 0 7 7 6 0 C2H2-type zinc finger zf-C2HE PF16278.5 KFP13280.1 - 0.046 14.2 37.3 0.19 12.2 0.3 6.9 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KFP13280.1 - 0.081 12.7 0.3 0.081 12.7 0.3 6.4 7 0 0 7 7 6 0 zinc-finger C2H2-type DUF3268 PF11672.8 KFP13280.1 - 0.89 9.9 14.2 1 9.7 0.3 4.0 3 1 1 4 4 4 0 zinc-finger-containing domain GAGA PF09237.11 KFP13280.1 - 1.3 8.9 17.2 7.2 6.5 0.0 5.1 1 1 4 5 5 5 0 GAGA factor RVT_1 PF00078.27 KFP13281.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2OG-FeII_Oxy_3 PF13640.6 KFP13282.1 - 4.1e-11 43.6 0.0 1.9e-10 41.5 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP13282.1 - 2.5e-09 37.5 0.0 1.8e-08 34.8 0.0 2.4 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KFP13282.1 - 0.0039 17.2 1.6 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFP13282.1 - 0.0072 16.4 6.7 1.6 9.1 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.6 KFP13282.1 - 0.013 15.3 5.1 0.19 11.4 0.1 2.9 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_1 PF00515.28 KFP13282.1 - 0.014 15.2 5.5 1.5 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Oxygenase-NA PF09859.9 KFP13282.1 - 0.037 13.5 0.0 0.51 9.8 0.0 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TPR_7 PF13176.6 KFP13282.1 - 0.04 14.0 3.0 7.7 6.8 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP13282.1 - 0.067 14.0 1.8 1.5 9.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PMP22_Claudin PF00822.20 KFP13283.1 - 7.5e-50 169.1 9.9 8.6e-50 168.9 9.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP13283.1 - 3.7e-10 39.9 12.2 3.1e-09 36.9 11.6 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4134 PF13572.6 KFP13283.1 - 0.0067 16.7 2.3 0.0067 16.7 2.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) DUF981 PF06168.11 KFP13283.1 - 0.012 15.5 4.1 0.18 11.7 4.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF981) CD20 PF04103.15 KFP13283.1 - 0.019 15.1 1.7 0.019 15.1 1.7 2.8 2 1 1 3 3 3 0 CD20-like family Cytochrom_B_C PF00032.17 KFP13283.1 - 0.065 13.5 1.8 0.093 13.0 0.4 1.9 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD OppC_N PF12911.7 KFP13283.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.7 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C SUR7 PF06687.12 KFP13283.1 - 0.26 10.9 6.7 0.085 12.5 3.3 1.8 1 1 1 2 2 2 0 SUR7/PalI family DUF2157 PF09925.9 KFP13283.1 - 0.38 10.5 0.1 0.38 10.5 0.1 3.1 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) HlyIII PF03006.20 KFP13283.1 - 0.96 9.1 4.8 2.2 7.9 3.3 2.1 1 1 1 2 2 2 0 Haemolysin-III related Gram_pos_anchor PF00746.21 KFP13283.1 - 2.6 8.0 7.5 28 4.8 0.4 3.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF4131 PF13567.6 KFP13283.1 - 5.2 6.7 6.3 5 6.7 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF1218 PF06749.12 KFP13283.1 - 6.5 7.4 10.9 1.2 9.7 1.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) PMP22_Claudin PF00822.20 KFP13284.1 - 7.6e-19 68.2 7.6 1e-18 67.8 7.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP13284.1 - 1.9e-06 27.8 12.7 7.4e-06 25.9 12.7 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 KFP13284.1 - 0.02 13.9 2.3 0.034 13.2 2.3 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor Phage_holin_3_6 PF07332.11 KFP13284.1 - 2.8 8.0 9.3 6.3 6.9 2.8 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM52 PF14979.6 KFP13285.1 - 1.5e-05 25.0 14.3 0.0084 16.0 10.2 2.1 1 1 1 2 2 2 2 Transmembrane 52 TMIE PF16038.5 KFP13285.1 - 0.75 9.7 4.3 1.1 9.1 4.3 1.2 1 0 0 1 1 1 0 TMIE protein TIR PF01582.20 KFP13286.1 - 2.7e-26 92.4 0.0 4.8e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 TIR domain Ig_6 PF18452.1 KFP13286.1 - 4e-21 74.3 1.2 3.4e-20 71.3 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KFP13286.1 - 2.4e-17 63.3 1.2 1e-08 35.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP13286.1 - 2.6e-13 49.9 1.2 3.4e-06 27.2 0.1 3.7 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP13286.1 - 1.6e-11 44.4 0.4 0.00085 19.6 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain TIR_2 PF13676.6 KFP13286.1 - 2.7e-10 40.9 0.0 6.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain I-set PF07679.16 KFP13286.1 - 3e-10 40.0 0.1 0.00038 20.5 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain RBD-FIP PF09457.10 KFP13287.1 - 0.0035 17.2 2.8 0.0071 16.2 2.8 1.4 1 0 0 1 1 1 1 FIP domain LRRFIP PF09738.9 KFP13287.1 - 0.18 11.2 3.3 0.27 10.7 3.3 1.2 1 0 0 1 1 1 0 LRRFIP family Musclin PF11037.8 KFP13288.1 - 6.9e-49 165.2 0.1 7.4e-49 165.1 0.1 1.0 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle ANP PF00212.18 KFP13288.1 - 6.7e-05 23.0 0.5 0.26 11.5 0.0 2.4 2 0 0 2 2 2 2 Atrial natriuretic peptide Urotensin_II PF02083.15 KFP13289.1 - 0.00013 21.4 4.8 0.00022 20.7 4.8 1.4 1 0 0 1 1 1 1 Urotensin II Dynactin_p22 PF07426.11 KFP13289.1 - 0.04 13.8 1.2 0.69 9.7 0.3 2.0 2 0 0 2 2 2 0 Dynactin subunit p22 CCDC50_N PF15295.6 KFP13290.1 - 5.9e-48 162.2 39.4 2e-41 141.1 26.2 2.3 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus Latexin PF06907.12 KFP13290.1 - 0.028 13.9 1.4 0.028 13.9 1.4 2.1 1 1 1 2 2 2 0 Latexin CLPTM1 PF05602.12 KFP13290.1 - 3 6.8 9.2 1.9 7.4 7.6 1.3 1 1 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) FGF PF00167.18 KFP13292.1 - 5.4e-38 129.9 0.0 7.4e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor CDtoxinA PF03498.14 KFP13292.1 - 0.062 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Fascin PF06268.13 KFP13292.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 Fascin domain Mab-21 PF03281.14 KFP13293.1 - 1.6e-33 116.3 0.2 2e-33 115.9 0.2 1.2 1 0 0 1 1 1 1 Mab-21 protein UCH PF00443.29 KFP13294.1 - 3.8e-49 167.5 0.6 8.6e-49 166.3 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP13294.1 - 1.3e-38 133.4 1.2 3.3e-38 132.1 1.2 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 KFP13294.1 - 3.7e-08 33.7 0.1 0.11 13.0 0.0 4.2 3 0 0 3 3 3 3 Ubiquitin-like domain ubiquitin PF00240.23 KFP13294.1 - 5.4e-07 29.3 0.1 0.16 11.8 0.0 3.9 3 0 0 3 3 3 2 Ubiquitin family DUF4487 PF14868.6 KFP13294.1 - 0.023 13.5 0.2 0.043 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) Sad1_UNC PF07738.13 KFP13294.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal YukD PF08817.10 KFP13294.1 - 0.057 14.1 0.0 10 6.9 0.0 2.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.8 KFP13294.1 - 0.094 13.2 0.4 19 5.9 0.0 3.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Dickkopf_N PF04706.12 KFP13295.1 - 1.8e-15 57.1 19.8 1.8e-15 57.1 19.8 3.1 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.11 KFP13295.1 - 1.4e-05 25.3 3.3 1.4e-05 25.3 3.3 2.7 1 1 2 3 3 3 1 Prokineticin Conotoxin_I2 PF17557.2 KFP13295.1 - 0.018 15.1 6.4 0.018 15.1 6.4 3.5 3 1 1 4 4 4 0 I2-superfamily conotoxins DUF3585 PF12130.8 KFP13296.1 - 4e-41 140.3 26.8 4e-41 140.3 26.8 2.1 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain IMUP PF15761.5 KFP13296.1 - 0.51 11.0 6.4 0.16 12.7 2.7 2.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein CH PF00307.31 KFP13297.1 - 5e-35 120.0 3.2 2.5e-18 66.2 1.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP13297.1 - 1.3e-05 24.9 0.0 0.066 13.0 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFP13297.1 - 2.4e-05 24.3 0.2 0.041 14.0 0.0 2.5 3 0 0 3 3 3 2 CH-like domain in sperm protein Sfi1 PF08457.10 KFP13297.1 - 0.13 10.7 0.3 0.22 10.0 0.3 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein FlaG PF03646.15 KFP13297.1 - 0.19 11.9 2.9 0.12 12.5 0.7 1.8 2 0 0 2 2 2 0 FlaG protein YBD PF17725.1 KFP13298.1 - 7.5e-100 333.0 1.2 1e-99 332.6 1.2 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFP13298.1 - 2.1e-27 95.0 0.0 4.3e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain PAS_11 PF14598.6 KFP13299.1 - 1.2e-26 93.1 0.4 9.3e-23 80.5 0.2 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFP13299.1 - 5.7e-21 74.6 0.0 2.8e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KFP13299.1 - 6.4e-20 71.2 0.0 8.5e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP13299.1 - 2.5e-16 59.3 0.8 4.4e-16 58.6 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP13299.1 - 1.9e-08 34.5 0.0 7.9e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFP13299.1 - 2.8e-05 24.3 0.0 0.01 16.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFP13299.1 - 0.025 15.3 0.0 0.091 13.4 0.0 1.9 2 0 0 2 2 2 0 PAS fold BTB_3 PF16017.5 KFP13300.1 - 1.5e-50 169.7 0.0 2.8e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KFP13300.1 - 0.00069 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Parathyroid PF01279.17 KFP13301.1 - 1.1e-07 32.4 2.3 1.4e-07 32.1 2.3 1.2 1 0 0 1 1 1 1 Parathyroid hormone family NAD_binding_4 PF07993.12 KFP13302.1 - 5.3e-76 255.2 0.0 6.9e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KFP13302.1 - 1.8e-28 98.6 5.0 1e-27 96.2 5.0 2.2 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFP13302.1 - 5.5e-09 35.8 0.1 3.7e-08 33.1 0.0 2.3 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFP13302.1 - 0.00018 21.9 0.0 0.00039 20.9 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFP13302.1 - 0.00053 19.2 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFP13302.1 - 0.00059 19.3 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFP13302.1 - 0.00062 18.9 0.0 0.055 12.5 0.1 2.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KFP13302.1 - 0.036 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 KFP13302.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFP13302.1 - 0.16 11.9 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding Trypsin PF00089.26 KFP13303.1 - 3.7e-141 468.3 0.1 1.6e-73 247.2 0.0 2.3 2 0 0 2 2 2 2 Trypsin CUB PF00431.20 KFP13303.1 - 1.9e-48 163.4 0.1 1.7e-24 86.2 0.1 2.6 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.11 KFP13303.1 - 4.2e-21 75.5 0.1 7e-11 42.5 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP13303.1 - 1.1e-11 45.8 0.0 0.00025 22.0 0.0 2.8 2 2 0 2 2 2 2 Trypsin-like peptidase domain CUB_2 PF02408.20 KFP13303.1 - 0.00085 19.1 0.0 0.28 11.0 0.0 2.6 2 0 0 2 2 2 2 CUB-like domain HD PF01966.22 KFP13303.1 - 0.087 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 HD domain NAD_binding_1 PF00175.21 KFP13304.1 - 2.8e-36 124.5 0.0 5.3e-36 123.6 0.0 1.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFP13304.1 - 9e-34 115.8 0.0 1.5e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFP13304.1 - 2.4e-06 27.7 0.0 3.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KFP13304.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SAM_1 PF00536.30 KFP13305.1 - 1.2e-40 137.7 6.1 3.3e-18 65.9 0.1 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP13305.1 - 7.7e-39 131.6 3.7 4.4e-15 55.6 0.0 4.0 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Myosin_tail_1 PF01576.19 KFP13305.1 - 0.00035 18.6 30.0 0.00052 18.0 30.0 1.2 1 0 0 1 1 1 1 Myosin tail DUF16 PF01519.16 KFP13305.1 - 0.0087 16.5 1.2 0.0087 16.5 1.2 3.1 2 1 0 2 2 2 1 Protein of unknown function DUF16 HMMR_N PF15905.5 KFP13305.1 - 0.0097 15.4 8.5 0.0097 15.4 8.5 2.3 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 KFP13305.1 - 0.016 15.1 1.7 0.016 15.1 1.7 4.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C4H2 PF10146.9 KFP13305.1 - 0.12 12.6 9.3 0.39 11.0 9.3 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein ADIP PF11559.8 KFP13305.1 - 0.21 11.7 30.4 1.2 9.2 18.4 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KFP13305.1 - 0.8 9.5 21.4 4.3 7.1 16.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF1192 PF06698.11 KFP13305.1 - 1.5 8.9 7.2 1.1 9.3 3.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Atg14 PF10186.9 KFP13305.1 - 4 6.4 30.0 0.2 10.7 19.1 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sortilin-Vps10 PF15902.5 KFP13306.1 - 7.4e-72 242.5 0.1 1.4e-71 241.6 0.0 1.4 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFP13306.1 - 1.6e-37 129.5 2.7 3.5e-37 128.4 2.7 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR_6 PF15899.5 KFP13306.1 - 2.4e-13 48.8 8.6 0.0073 16.3 0.1 5.4 5 0 0 5 5 5 3 BNR-Asp box repeat BNR PF02012.20 KFP13306.1 - 9.3e-07 27.9 4.0 0.89 9.8 0.0 5.4 5 0 0 5 5 5 3 BNR/Asp-box repeat Mo-co_dimer PF03404.16 KFP13306.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain Proteasome PF00227.26 KFP13307.1 - 8.1e-56 188.5 0.0 9.6e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP13307.1 - 1.4e-11 43.9 0.0 2.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Methyltransf_16 PF10294.9 KFP13308.1 - 4.7e-17 62.3 0.1 5.6e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 KFP13308.1 - 0.00039 21.0 0.0 0.00066 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP13308.1 - 0.00042 21.0 0.0 0.00071 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP13308.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.12 KFP13308.1 - 0.0038 16.6 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_12 PF08242.12 KFP13308.1 - 0.0048 17.6 0.1 0.014 16.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP13308.1 - 0.11 12.0 0.3 0.21 11.1 0.3 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Sensor_TM1 PF13755.6 KFP13308.1 - 0.12 12.1 0.1 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Tex_N PF09371.10 KFP13309.1 - 5.6e-48 163.0 0.5 9.7e-48 162.2 0.5 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KFP13309.1 - 7.4e-45 152.5 0.0 2.1e-44 151.0 0.0 1.8 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 KFP13309.1 - 8.6e-25 86.8 0.0 2.3e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KFP13309.1 - 1.2e-09 38.4 0.3 2.4e-09 37.4 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 KFP13309.1 - 4.3e-09 37.1 0.1 1.9e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 HHH domain HHH_7 PF14635.6 KFP13309.1 - 3.3e-06 27.4 0.0 9.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KFP13309.1 - 9.7e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 KFP13309.1 - 0.0082 16.4 0.3 0.074 13.3 0.0 2.7 3 1 1 4 4 4 1 Helix-hairpin-helix motif RuvX PF03652.15 KFP13309.1 - 0.049 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Holliday junction resolvase RVT_1 PF00078.27 KFP13310.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KFP13311.1 - 2.1e-15 56.9 0.0 2.3e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KFP13312.1 - 8.6e-35 118.4 22.9 8e-18 64.1 5.4 2.1 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KFP13312.1 - 0.0027 18.0 17.4 0.094 13.0 3.2 2.5 2 0 0 2 2 2 2 C1 domain Zf_RING PF16744.5 KFP13312.1 - 0.0079 16.3 13.6 0.15 12.2 4.6 2.4 2 0 0 2 2 2 2 KIAA1045 RING finger DZR PF12773.7 KFP13312.1 - 0.022 14.8 2.3 0.022 14.8 2.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon PHD_2 PF13831.6 KFP13312.1 - 0.06 12.9 1.4 0.06 12.9 1.4 4.6 5 0 0 5 5 5 0 PHD-finger PHD PF00628.29 KFP13312.1 - 0.27 11.2 21.9 0.26 11.2 4.9 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 KFP13312.1 - 1.8 8.8 16.2 1.7 8.9 4.5 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger DUF2321 PF10083.9 KFP13312.1 - 6.7 6.3 11.4 1.3 8.6 1.4 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) PAS_3 PF08447.12 KFP13313.1 - 2.1e-27 95.2 0.0 1.3e-20 73.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP13313.1 - 2.3e-22 79.2 0.2 4.9e-19 68.5 0.1 2.5 2 0 0 2 2 2 2 PAS domain HIF-1a_CTAD PF08778.10 KFP13313.1 - 1.7e-19 69.1 0.8 4.7e-19 67.7 0.8 1.8 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.8 KFP13313.1 - 9.2e-18 63.4 2.1 2e-17 62.2 2.1 1.6 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 PAS PF00989.25 KFP13313.1 - 4.4e-14 52.4 0.0 3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFP13313.1 - 2.1e-08 34.3 0.0 0.0074 16.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFP13313.1 - 4.4e-07 30.1 0.0 0.038 14.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP13313.1 - 0.075 13.0 0.4 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Corona_I PF03187.14 KFP13313.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Corona nucleocapsid I protein PIG-F PF06699.11 KFP13314.1 - 1.6e-45 155.5 12.0 2e-45 155.1 12.0 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Cript PF10235.9 KFP13315.1 - 6.6e-25 87.5 0.7 7.3e-25 87.4 0.7 1.0 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT SOCS PF12610.8 KFP13316.1 - 4.2e-15 55.9 2.2 4.2e-15 55.9 2.2 2.7 3 0 0 3 3 3 1 Suppressor of cytokine signalling SOCS_box PF07525.16 KFP13316.1 - 1.9e-09 37.7 0.1 3.8e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 SOCS box SH2 PF00017.24 KFP13316.1 - 5.2e-09 36.1 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain EF-hand_6 PF13405.6 KFP13317.1 - 1.4e-09 37.1 0.3 0.00035 20.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFP13317.1 - 1.7e-08 34.8 2.4 3e-08 34.0 1.2 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP13317.1 - 3.4e-07 29.3 0.2 0.00091 18.6 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP13317.1 - 0.00034 20.0 0.3 0.011 15.2 0.0 2.9 2 1 1 3 3 3 1 EF hand EF-hand_8 PF13833.6 KFP13317.1 - 0.02 14.7 1.2 0.074 12.9 0.2 2.4 2 2 0 2 2 2 0 EF-hand domain pair CLLAC PF15675.5 KFP13317.1 - 1.1 8.9 3.8 0.23 11.1 0.7 1.5 2 0 0 2 2 2 0 CLLAC-motif containing domain RVT_1 PF00078.27 KFP13318.1 - 6.3e-05 22.6 0.0 9.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP13319.1 - 0.0067 16.0 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_B PF00136.21 KFP13320.1 - 3.8e-131 438.0 1.6 5.3e-131 437.5 1.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFP13320.1 - 6.5e-57 193.2 0.0 1.7e-56 191.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 KFP13320.1 - 1.2e-53 181.6 5.3 2.4e-53 180.6 5.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 KFP13320.1 - 4.4e-16 58.7 11.4 4.4e-16 58.7 11.4 3.3 4 0 0 4 4 4 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 KFP13320.1 - 0.00038 19.1 0.3 0.0011 17.6 0.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_2 PF03175.13 KFP13320.1 - 0.0012 17.8 0.0 0.0038 16.2 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral CTP_transf_like PF01467.26 KFP13321.1 - 5.3e-32 111.0 0.4 1e-31 110.1 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like Lipoprotein_6 PF01441.19 KFP13321.1 - 0.073 13.1 1.9 0.12 12.4 1.9 1.2 1 0 0 1 1 1 0 Lipoprotein YtxH PF12732.7 KFP13321.1 - 0.13 12.8 1.9 0.27 11.8 1.9 1.5 1 0 0 1 1 1 0 YtxH-like protein BCDHK_Adom3 PF10436.9 KFP13322.1 - 4.7e-46 156.6 0.0 7e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFP13322.1 - 5.2e-13 49.5 0.0 8.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP13322.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Solute_trans_a PF03619.16 KFP13323.1 - 5.8e-42 144.1 21.4 7.1e-42 143.8 21.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2427 PF10348.9 KFP13323.1 - 4.6 7.1 17.0 0.15 11.8 0.6 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF2427) Zfx_Zfy_act PF04704.13 KFP13324.1 - 6.3e-152 505.4 18.9 6.3e-152 505.4 18.9 1.6 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-C2H2 PF00096.26 KFP13324.1 - 2.2e-42 141.2 117.6 1e-05 25.7 2.1 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP13324.1 - 1e-38 130.0 122.8 2.7e-08 33.9 1.2 13.7 14 0 0 14 14 13 12 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP13324.1 - 1.2e-32 109.8 111.6 0.00016 22.2 0.9 13.4 13 0 0 13 13 13 13 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP13324.1 - 5.8e-24 83.5 111.8 4.4e-07 29.5 5.8 12.8 12 2 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP13324.1 - 4e-12 46.1 76.3 0.028 14.7 0.1 12.4 13 0 0 13 13 12 7 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KFP13324.1 - 6.6e-08 33.2 48.6 0.028 15.2 2.4 7.3 4 2 3 7 7 7 4 zinc-ribbon family zf-C2H2_3rep PF18868.1 KFP13324.1 - 0.0018 19.0 44.8 0.17 12.5 5.7 7.8 3 2 4 7 7 7 3 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KFP13324.1 - 0.0049 16.8 2.5 0.0049 16.8 2.5 10.2 4 3 6 11 11 11 5 BED zinc finger zf-C2H2_11 PF16622.5 KFP13324.1 - 0.021 14.6 0.2 0.021 14.6 0.2 10.1 13 0 0 13 13 13 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP13324.1 - 0.022 14.8 3.3 0.022 14.8 3.3 10.2 11 0 0 11 11 10 0 C2H2-type zinc finger zf-met PF12874.7 KFP13324.1 - 0.15 12.5 0.0 0.15 12.5 0.0 11.4 12 1 0 12 12 11 0 Zinc-finger of C2H2 type BolA PF01722.18 KFP13324.1 - 0.58 10.5 5.4 0.31 11.3 0.9 3.0 4 0 0 4 4 2 0 BolA-like protein zf-RING_7 PF02591.15 KFP13324.1 - 2.5 8.4 11.8 27 5.1 0.1 5.8 5 0 0 5 5 5 0 C4-type zinc ribbon domain eIF2_C PF09173.11 KFP13325.1 - 4.9e-31 106.8 1.4 8.1e-31 106.1 0.2 2.0 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFP13325.1 - 4.2e-23 81.9 1.1 3.8e-22 78.8 1.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFP13325.1 - 6.1e-13 49.0 0.3 1.6e-12 47.6 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KFP13325.1 - 0.0028 17.6 0.4 0.023 14.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFP13325.1 - 0.0029 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KFP13325.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 KFP13325.1 - 0.1 11.7 0.1 0.78 8.8 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 KFP13325.1 - 0.13 12.4 0.3 0.6 10.1 0.1 2.0 1 1 0 2 2 2 0 Dynamin family Kelch_1 PF01344.25 KFP13326.1 - 9.6e-40 133.9 7.4 3.2e-10 39.4 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP13326.1 - 2.6e-33 113.2 4.1 2.5e-07 30.7 0.2 6.2 3 2 2 5 5 5 5 Kelch motif BTB PF00651.31 KFP13326.1 - 1.5e-23 83.2 1.9 1.5e-23 83.2 1.9 2.2 3 0 0 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.6 KFP13326.1 - 7.6e-20 70.7 0.9 0.0049 16.9 0.0 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP13326.1 - 1.8e-17 63.2 0.6 0.00036 20.7 0.1 5.7 5 2 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.15 KFP13326.1 - 5.8e-16 58.5 0.9 8.1e-16 58.0 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP13326.1 - 1.2e-13 50.4 11.0 0.0012 18.8 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFP13326.1 - 1.8e-08 34.1 8.6 0.062 13.3 0.0 5.3 5 0 0 5 5 5 4 Kelch motif ApoO PF09769.9 KFP13327.1 - 2.1e-36 124.8 0.0 2.3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein O Acetyltransf_1 PF00583.25 KFP13328.1 - 9.8e-17 61.3 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFP13328.1 - 6.9e-08 32.8 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFP13328.1 - 3.6e-05 23.7 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP13328.1 - 0.00044 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFP13328.1 - 0.015 16.0 0.0 0.017 15.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 4HBT PF03061.22 KFP13329.1 - 9.8e-09 35.5 0.0 0.0039 17.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily AhpC-TSA PF00578.21 KFP13330.1 - 1.1e-34 119.0 0.0 1.4e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP13330.1 - 1.4e-12 47.6 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFP13330.1 - 8e-11 41.6 0.1 2.2e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Patched PF02460.18 KFP13331.1 - 2.6e-95 320.2 23.0 4.5e-95 319.4 23.0 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFP13331.1 - 2e-19 69.9 1.6 2e-19 69.9 1.6 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Peptidase_M13_N PF05649.13 KFP13332.1 - 3.3e-110 369.4 1.6 4.2e-110 369.0 1.6 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP13332.1 - 5.6e-65 218.8 0.6 7.7e-65 218.3 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M13 DED PF01335.21 KFP13332.1 - 0.087 13.1 0.1 0.32 11.3 0.1 1.9 1 0 0 1 1 1 0 Death effector domain UQ_con PF00179.26 KFP13333.1 - 1.5e-37 128.3 0.0 1.9e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 KFP13333.1 - 0.14 12.5 1.2 0.27 11.6 0.9 1.6 1 1 0 2 2 2 0 Uteroglobin family zf-C3HC PF07967.13 KFP13334.1 - 5.6e-35 120.3 10.3 1.7e-34 118.7 1.4 3.4 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.10 KFP13334.1 - 1.1e-14 54.4 10.2 7.2e-10 38.9 0.2 3.4 3 0 0 3 3 3 2 Rsm1-like Kelch_1 PF01344.25 KFP13335.1 - 4.6e-41 138.2 10.6 3.7e-09 36.0 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP13335.1 - 3.3e-38 128.7 7.0 4.5e-07 29.9 0.0 5.9 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP13335.1 - 9.8e-36 121.5 11.6 4.2e-10 39.5 0.0 5.8 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP13335.1 - 2.4e-32 110.4 7.7 1.3e-05 25.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP13335.1 - 1.8e-31 107.8 13.1 2.1e-07 31.1 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP13335.1 - 7e-26 89.2 14.9 1.6e-06 27.9 0.1 6.8 5 2 1 6 6 6 6 Kelch motif Na_Ca_ex PF01699.24 KFP13336.1 - 6.3e-19 68.4 28.8 3.9e-14 52.9 15.4 3.9 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KFP13336.1 - 1.8e-18 67.0 16.2 1.8e-18 67.0 16.2 5.7 5 1 1 6 6 6 2 Inner membrane component domain Peptidase_M14 PF00246.24 KFP13337.1 - 4.4e-84 282.7 0.0 7.1e-84 282.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP13337.1 - 7e-21 74.4 0.4 1.3e-20 73.5 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Phage_min_tail PF05939.13 KFP13337.1 - 0.044 14.2 0.0 14 6.1 0.0 2.7 3 0 0 3 3 3 0 Phage minor tail protein nec1 PF10379.9 KFP13337.1 - 0.2 11.1 1.4 1 8.9 0.4 2.1 2 0 0 2 2 2 0 Virulence protein nec1 Peptidase_M14 PF00246.24 KFP13338.1 - 9.7e-91 304.6 0.1 1.2e-90 304.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP13338.1 - 8e-22 77.4 0.2 1.9e-21 76.2 0.2 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide P_C PF06640.11 KFP13338.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 P protein C-terminus Rhodanese PF00581.20 KFP13339.1 - 1.1e-11 45.2 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Utp14 PF04615.13 KFP13340.1 - 5.1e-153 511.5 47.6 1.3e-84 285.2 33.9 2.0 1 1 1 2 2 2 2 Utp14 protein DUF4752 PF15944.5 KFP13340.1 - 5 7.3 5.9 16 5.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) PUFD PF16553.5 KFP13341.1 - 1.4e-43 147.7 0.3 2.7e-43 146.8 0.3 1.5 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Ank_2 PF12796.7 KFP13341.1 - 3.6e-20 72.3 5.9 1.6e-11 44.6 0.3 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP13341.1 - 1.4e-12 47.9 4.0 6.6e-07 29.8 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP13341.1 - 3.7e-11 42.2 0.4 2.7e-05 24.2 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFP13341.1 - 3.5e-09 36.7 1.3 7.9e-05 22.9 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP13341.1 - 1.4e-08 34.8 2.2 0.00013 22.2 0.4 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) MARVEL PF01284.23 KFP13342.1 - 0.00064 19.8 3.6 0.00089 19.3 3.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain zf-CCHC PF00098.23 KFP13343.1 - 2.3e-06 27.4 2.4 8e-06 25.7 2.4 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KFP13343.1 - 0.21 11.6 1.7 0.49 10.4 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFP13343.1 - 0.25 11.2 2.6 0.56 10.1 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KFP13343.1 - 1.6 8.5 5.1 0.26 11.0 1.1 1.8 2 0 0 2 2 2 0 Zinc knuckle RANK_CRD_2 PF18278.1 KFP13344.1 - 6.8e-28 96.5 7.1 6.8e-28 96.5 7.1 2.6 2 0 0 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 TNFR_c6 PF00020.18 KFP13344.1 - 1.1e-15 57.7 36.9 0.0001 22.6 0.1 4.6 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region HEAT PF02985.22 KFP13345.1 - 3.2e-16 58.0 0.8 0.011 16.0 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KFP13345.1 - 1e-08 35.4 0.1 0.00058 20.2 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KFP13345.1 - 0.00025 21.5 2.3 0.27 11.8 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 KFP13345.1 - 0.036 14.1 0.2 3 7.9 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KFP13345.1 - 0.088 12.7 1.8 0.79 9.6 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Nuc_H_symport PF03825.16 KFP13345.1 - 0.12 11.3 0.1 5.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoside H+ symporter DUF4128 PF13554.6 KFP13345.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function TMF_TATA_bd PF12325.8 KFP13345.1 - 0.35 11.1 5.4 0.59 10.4 0.4 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KFP13345.1 - 1.9 8.3 6.3 1.7 8.5 0.3 2.6 2 0 0 2 2 2 0 Septum formation initiator PigN PF04987.14 KFP13346.1 - 3.1e-137 458.2 47.3 4.1e-137 457.8 47.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KFP13346.1 - 6e-15 55.7 0.7 1.4e-13 51.2 0.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFP13346.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFP13346.1 - 6.5e-05 22.5 0.1 0.00013 21.5 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Cadherin PF00028.17 KFP13347.1 - 3.8e-83 274.1 2.5 2.1e-18 66.6 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP13347.1 - 5.1e-52 176.1 0.2 1.1e-51 175.0 0.2 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP13347.1 - 6.2e-07 29.4 4.7 0.39 10.7 0.0 5.0 5 0 0 5 5 5 3 Cadherin-like Cadherin_2 PF08266.12 KFP13347.1 - 6e-06 26.0 0.0 0.32 10.8 0.0 4.3 4 0 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 KFP13347.1 - 0.044 14.4 15.3 0.28 11.8 0.4 4.5 4 1 0 4 4 4 0 Bacterial cadherin-like domain Invasin_D3 PF09134.10 KFP13347.1 - 2 8.8 5.6 46 4.4 0.0 4.3 6 0 0 6 6 6 0 Invasin, domain 3 7tm_1 PF00001.21 KFP13348.1 - 5.1e-36 124.3 34.3 1.3e-34 119.7 34.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP13348.1 - 5.2e-11 42.8 24.9 1.6e-10 41.2 17.0 2.5 1 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP13348.1 - 1.3e-10 41.1 33.8 2.6e-10 40.1 33.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP13348.1 - 0.00094 18.9 24.6 0.00094 18.9 24.6 2.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0489 PF12640.7 KFP13349.1 - 4.4e-58 196.4 0.1 8.7e-58 195.5 0.1 1.5 1 0 0 1 1 1 1 UPF0489 domain Ribonucleas_3_3 PF14622.6 KFP13350.1 - 5.4e-44 149.5 0.7 4.6e-24 85.0 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFP13350.1 - 1.1e-42 144.9 0.3 1.1e-20 74.2 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 KFP13350.1 - 5.4e-15 55.8 0.0 2.1e-14 54.0 0.0 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cadherin PF00028.17 KFP13351.1 - 1.1e-76 253.3 11.3 4e-19 68.8 0.2 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP13351.1 - 6.8e-59 198.4 0.7 1.4e-58 197.3 0.7 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP13351.1 - 9.6e-08 32.0 7.2 0.079 13.0 0.1 5.5 5 1 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 KFP13351.1 - 1.2e-05 25.8 21.8 0.0052 17.4 2.3 4.9 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFP13351.1 - 6.4e-05 22.7 0.0 1.2 9.0 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like Invasin_D3 PF09134.10 KFP13351.1 - 0.0053 17.0 3.6 9.1 6.7 0.1 4.8 4 0 0 4 4 4 1 Invasin, domain 3 ASFV_J13L PF05568.11 KFP13351.1 - 0.0056 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein Stevor PF17410.2 KFP13351.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srw PF10324.9 KFP13351.1 - 0.1 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Big_9 PF17963.1 KFP13351.1 - 0.99 10.2 21.6 0.36 11.6 1.9 4.7 5 0 0 5 5 5 0 Bacterial Ig domain Leu_zip PF15294.6 KFP13352.1 - 2.2e-125 417.8 31.7 2.5e-125 417.6 31.7 1.0 1 0 0 1 1 1 1 Leucine zipper RBD PF02196.15 KFP13352.1 - 0.094 12.8 0.4 0.43 10.7 0.1 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain HisKA_3 PF07730.13 KFP13352.1 - 0.57 10.7 4.3 23 5.6 0.4 2.9 2 0 0 2 2 2 0 Histidine kinase LSM PF01423.22 KFP13353.1 - 4e-19 68.1 0.7 6.1e-19 67.5 0.7 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFP13353.1 - 0.0093 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Gemin7 PF11095.8 KFP13353.1 - 0.041 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.6 KFP13353.1 - 0.048 13.8 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 KFP13353.1 - 1.7 7.4 3.3 2.2 7.0 3.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Syja_N PF02383.18 KFP13354.1 - 1.2e-94 317.3 0.6 1.5e-94 316.9 0.6 1.1 1 0 0 1 1 1 1 SacI homology domain LIM PF00412.22 KFP13355.1 - 4.9e-33 113.2 34.5 9.3e-13 48.2 5.7 3.2 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 KFP13355.1 - 0.19 11.8 14.3 2.1 8.4 0.8 3.7 2 1 2 4 4 4 0 Mut7-C RNAse domain tRNA-synt_1 PF00133.22 KFP13356.1 - 5.1e-48 163.7 4.7 1.6e-23 82.8 7.9 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFP13356.1 - 2.4e-31 108.9 0.1 1.6e-20 73.3 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFP13356.1 - 1.4e-11 44.5 0.2 3e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KFP13356.1 - 1.3e-08 34.5 0.0 2.5e-06 27.1 0.0 2.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFP13356.1 - 0.00051 19.5 0.0 0.43 9.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KFP13356.1 - 0.02 13.9 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) CUB PF00431.20 KFP13357.1 - 0.00035 20.9 0.0 3 8.2 0.0 3.9 5 0 0 5 5 5 2 CUB domain CYYR1 PF10873.8 KFP13357.1 - 0.19 12.2 5.3 1.7 9.1 0.1 2.6 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Chordopox_A33R PF05966.12 KFP13358.1 - 0.00025 20.4 0.1 0.00031 20.1 0.1 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 KFP13358.1 - 0.00029 21.5 0.0 0.00051 20.8 0.0 1.4 1 0 0 1 1 1 1 Lectin C-type domain DUF333 PF03891.15 KFP13358.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF333) RNase_PH PF01138.21 KFP13359.1 - 2.1e-23 83.3 0.0 3.3e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP13359.1 - 2.3e-11 43.6 0.1 6.5e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DHHC PF01529.20 KFP13360.1 - 3.7e-37 127.4 14.2 3.7e-37 127.4 14.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3615 PF12274.8 KFP13360.1 - 0.0036 17.8 0.9 0.0068 16.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3615) IGFBP PF00219.18 KFP13360.1 - 2.7 8.7 13.6 34 5.2 10.5 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein Transglut_N PF00868.20 KFP13361.1 - 1.9e-32 112.1 0.0 5.4e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP13361.1 - 7.1e-20 71.1 0.4 5.6e-12 45.7 0.1 3.0 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP13361.1 - 4.7e-15 56.0 0.1 9.2e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily APS-reductase_C PF12139.8 KFP13361.1 - 0.025 14.8 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit Kinesin PF00225.23 KFP13362.1 - 2.3e-106 355.5 0.1 2.3e-106 355.5 0.1 4.0 3 1 1 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 KFP13362.1 - 1e-27 96.9 0.4 1.2e-25 90.2 0.0 3.8 2 0 0 2 2 2 1 Microtubule binding HMMR_C PF15908.5 KFP13362.1 - 5.8e-09 36.4 12.8 5.8e-09 36.4 12.8 9.5 5 2 1 9 9 9 1 Hyaluronan mediated motility receptor C-terminal ADIP PF11559.8 KFP13362.1 - 0.0035 17.4 12.8 0.0035 17.4 12.8 12.4 5 3 6 13 13 13 3 Afadin- and alpha -actinin-Binding DUF4604 PF15377.6 KFP13363.1 - 7.6e-28 98.1 13.0 9.6e-28 97.8 13.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Arm PF00514.23 KFP13364.1 - 2e-44 148.3 18.6 9e-08 31.9 0.1 12.3 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFP13364.1 - 1.4e-08 34.9 1.4 0.0058 16.7 0.3 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP13364.1 - 6.2e-07 29.2 2.1 12 6.5 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 KFP13364.1 - 1.5e-06 27.1 2.1 0.00085 18.0 1.1 3.2 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 KFP13364.1 - 1.5e-06 28.5 6.6 0.029 14.8 0.4 5.1 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 KFP13364.1 - 1.7e-05 25.2 8.2 0.64 10.6 0.3 6.3 4 2 2 6 6 6 2 HEAT-like repeat KAP PF05804.12 KFP13364.1 - 0.00013 20.3 1.4 0.033 12.3 0.0 3.4 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) DUF3361 PF11841.8 KFP13364.1 - 0.00056 19.9 2.3 1.7 8.6 0.0 4.7 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFP13364.1 - 0.0016 18.4 2.0 0.018 15.0 0.2 3.5 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KFP13364.1 - 0.005 17.2 6.8 6.2 7.3 0.0 5.0 5 2 1 6 6 5 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm_2 PF04826.13 KFP13364.1 - 0.013 15.0 3.8 0.61 9.5 0.0 3.6 2 1 1 3 3 3 0 Armadillo-like Queuosine_synth PF02547.15 KFP13364.1 - 0.017 14.2 0.5 0.037 13.1 0.1 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein MMS19_N PF14500.6 KFP13365.1 - 0.011 15.3 1.1 0.14 11.7 0.3 2.3 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Sec7_N PF12783.7 KFP13365.1 - 0.24 11.3 8.3 0.99 9.3 3.4 2.7 1 1 2 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 KFP13365.1 - 0.53 10.2 6.8 0.29 11.1 3.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) UBX PF00789.20 KFP13366.1 - 1.7e-21 76.2 0.1 3.8e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 UBX domain Borrelia_P83 PF05262.11 KFP13366.1 - 0.2 10.1 6.5 0.26 9.7 6.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 KFP13366.1 - 0.59 10.6 7.1 0.98 9.9 7.1 1.3 1 0 0 1 1 1 0 AAA domain Mitofilin PF09731.9 KFP13366.1 - 1.1 8.0 13.3 1.6 7.5 13.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RRM_1 PF00076.22 KFP13367.1 - 3.7e-66 218.9 0.1 4.1e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP13367.1 - 8.4e-13 48.0 0.0 3.2e-05 23.5 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP13367.1 - 3.7e-05 23.9 0.0 0.49 10.6 0.0 2.8 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 KFP13367.1 - 0.0003 20.6 0.0 1.1 9.2 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP13367.1 - 0.0026 17.8 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KFP13367.1 - 0.0051 16.9 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RNA_bind PF08675.11 KFP13367.1 - 0.06 13.4 0.0 2.7 8.1 0.0 2.7 2 1 0 2 2 2 0 RNA binding domain RRM_2 PF04059.12 KFP13367.1 - 0.14 12.4 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 Pepdidase_M14_N PF18027.1 KFP13368.1 - 1.9e-06 28.2 0.0 2.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain BEN PF10523.9 KFP13370.1 - 1e-15 57.7 0.1 2.5e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 BEN domain T4SS PF07996.11 KFP13370.1 - 0.0046 17.4 1.3 0.0086 16.5 0.6 1.8 2 0 0 2 2 2 1 Type IV secretion system proteins Sec8_exocyst PF04048.14 KFP13370.1 - 0.026 14.4 2.4 0.074 12.9 2.4 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FAD-SLDH PF12318.8 KFP13370.1 - 0.17 11.9 0.6 0.36 10.9 0.6 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase PIN_12 PF16289.5 KFP13370.1 - 0.28 11.7 4.8 0.054 14.0 0.8 2.0 2 0 0 2 2 2 0 PIN domain TSNAXIP1_N PF15739.5 KFP13370.1 - 1.1 9.6 10.4 0.52 10.7 6.5 2.4 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus SPATA6 PF14909.6 KFP13371.1 - 3.5e-54 182.7 0.1 5.5e-54 182.1 0.1 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 TraB PF01963.17 KFP13372.1 - 7.2e-38 131.0 0.0 8.2e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 TraB family TraB PF01963.17 KFP13373.1 - 7.1e-24 85.1 0.0 7.7e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 TraB family Forkhead PF00250.18 KFP13375.1 - 5.8e-39 132.2 0.0 6.6e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain ADK PF00406.22 KFP13376.1 - 2.3e-33 115.4 0.0 3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFP13376.1 - 1.7e-27 96.5 0.0 2.4e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFP13376.1 - 0.0056 16.4 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KFP13376.1 - 0.015 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain STIL_N PF15253.6 KFP13377.1 - 1.1e-208 693.1 0.0 1.6e-208 692.6 0.0 1.2 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus zf-Tim10_DDP PF02953.15 KFP13378.1 - 4.9e-17 61.3 0.4 6.6e-17 60.9 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger POB3_N PF17292.2 KFP13379.1 - 3.4e-29 101.1 0.5 1.8e-25 89.1 0.2 2.9 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFP13379.1 - 4.6e-28 97.5 0.1 5.6e-27 94.0 0.1 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KFP13379.1 - 5.8e-28 96.6 0.0 1.5e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 KFP13379.1 - 1e-24 86.7 6.0 1e-24 86.7 6.0 2.8 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP13379.1 - 4.8e-13 49.5 5.5 4.8e-13 49.5 5.5 2.9 3 0 0 3 3 3 1 HMG-box domain Tankyrase_bdg_C PF15327.6 KFP13380.1 - 5.4e-52 176.7 10.6 6.3e-52 176.5 10.6 1.0 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain Svs_4_5_6 PF17381.2 KFP13380.1 - 0.028 15.4 0.2 0.045 14.7 0.2 1.4 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 INCENP_ARK-bind PF03941.15 KFP13381.1 - 3.5e-21 74.9 0.3 9.2e-21 73.5 0.3 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Uteroglobin PF01099.17 KFP13382.1 - 1.4e-12 47.8 0.0 1.4e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Uteroglobin family DUF3446 PF11928.8 KFP13384.1 - 4.7e-13 49.2 3.9 4.7e-13 49.2 3.9 1.7 2 0 0 2 2 2 1 Early growth response N-terminal domain BTB PF00651.31 KFP13385.1 - 7.7e-28 96.9 2.1 5.6e-13 49.1 0.0 3.6 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.22 KFP13385.1 - 1.4e-24 86.5 0.0 2.9e-24 85.5 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFP13385.1 - 2.9e-10 40.4 0.0 6.5e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Snf7 PF03357.21 KFP13386.1 - 6.1e-24 84.6 5.8 6.1e-24 84.6 5.8 2.2 1 1 1 2 2 2 1 Snf7 PspA_IM30 PF04012.12 KFP13386.1 - 6.9e-06 25.8 0.4 6.9e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 PspA/IM30 family DUF763 PF05559.11 KFP13386.1 - 0.053 12.7 1.1 0.088 12.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) AAA_27 PF13514.6 KFP13386.1 - 0.059 13.0 0.7 0.3 10.6 0.1 2.3 1 1 2 3 3 3 0 AAA domain Fez1 PF06818.15 KFP13386.1 - 0.072 13.5 10.2 0.7 10.3 10.2 2.2 1 1 0 1 1 1 0 Fez1 LPP PF04728.13 KFP13386.1 - 0.56 10.6 7.1 2.7 8.4 0.2 3.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.18 KFP13386.1 - 0.64 9.9 9.9 5.6 6.8 9.7 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Fmp27_WPPW PF10359.9 KFP13386.1 - 0.67 8.7 4.8 0.88 8.3 3.9 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.11 KFP13386.1 - 0.81 9.2 3.3 12 5.3 0.6 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.6 KFP13386.1 - 0.9 10.0 11.3 0.89 10.0 2.8 3.7 3 1 0 3 3 3 0 Snapin/Pallidin RUN PF02759.19 KFP13386.1 - 1.2 9.1 5.8 7.6 6.5 0.2 3.1 2 1 0 2 2 2 0 RUN domain Not3 PF04065.15 KFP13386.1 - 1.4 8.3 7.0 1.9 7.9 2.0 2.8 2 1 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component RNase_H2-Ydr279 PF09468.10 KFP13386.1 - 3.2 7.9 6.0 1.4e+02 2.6 6.0 2.8 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF2120 PF09893.9 KFP13386.1 - 3.3 7.8 5.6 6.1 7.0 0.5 3.1 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) 7tm_1 PF00001.21 KFP13387.1 - 1.4e-72 244.2 14.1 1.8e-72 243.8 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP13387.1 - 2.2e-08 33.8 13.0 2.9e-07 30.1 13.0 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP13387.1 - 1.1e-06 28.5 10.3 1.1e-06 28.5 10.3 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 KFP13387.1 - 0.51 9.5 16.7 0.033 13.4 11.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF621) R3H PF01424.22 KFP13388.1 - 4.1e-14 52.3 0.1 8.5e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 KFP13388.1 - 7.9e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RgpF PF05045.12 KFP13388.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F GDA1_CD39 PF01150.17 KFP13389.1 - 4.1e-95 319.0 0.0 5.4e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adhesin_E PF16747.5 KFP13389.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Surface-adhesin protein E Mito_carr PF00153.27 KFP13390.1 - 1.7e-53 178.5 4.7 3.3e-21 75.0 0.6 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP13390.1 - 0.043 13.0 1.4 0.082 12.0 0.3 1.9 1 1 1 2 2 2 0 Gammaproteobacterial serine protease Stanniocalcin PF03298.13 KFP13391.1 - 1.2e-100 334.9 5.7 1.4e-100 334.7 5.7 1.0 1 0 0 1 1 1 1 Stanniocalcin family DUF4462 PF14692.6 KFP13392.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP13393.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Filament PF00038.21 KFP13394.1 - 4e-91 305.9 41.3 4e-91 305.9 41.3 2.9 4 0 0 4 4 4 1 Intermediate filament protein DUF1664 PF07889.12 KFP13394.1 - 0.0013 18.8 2.9 0.0013 18.8 2.9 4.4 5 1 1 6 6 6 3 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 KFP13394.1 - 0.0014 18.6 31.9 0.31 11.2 5.2 4.8 3 1 1 4 4 4 3 TolA binding protein trimerisation Spc29 PF17082.5 KFP13394.1 - 0.0039 17.1 3.0 0.0039 17.1 3.0 2.6 1 1 1 2 2 2 1 Spindle Pole Component 29 Lectin_N PF03954.14 KFP13394.1 - 1.1 9.1 8.4 6.6 6.5 2.3 3.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 KFP13394.1 - 1.1 9.8 11.0 0.088 13.3 0.9 3.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DOCK-C2 PF14429.6 KFP13396.1 - 3.4e-36 124.9 0.1 5.8e-36 124.1 0.0 1.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 KFP13396.1 - 4.4e-11 42.3 0.0 5.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus IRK_C PF17655.1 KFP13396.1 - 0.053 13.1 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel C-terminal domain DUF4462 PF14692.6 KFP13397.1 - 0.054 13.0 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DHR-2 PF06920.13 KFP13398.1 - 0.053 12.2 0.4 0.071 11.7 0.1 1.4 2 0 0 2 2 2 0 Dock homology region 2 GnRH PF00446.17 KFP13399.1 - 7.8e-05 22.7 2.1 0.00014 22.0 2.1 1.4 1 0 0 1 1 1 1 Gonadotropin-releasing hormone Pentapeptide PF00805.22 KFP13400.1 - 2.5e-40 135.6 28.7 3.2e-13 49.0 1.9 4.1 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KFP13400.1 - 6.6e-17 61.5 0.5 2e-10 40.7 0.0 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KFP13400.1 - 3.3e-13 49.6 0.0 1.9e-06 27.9 0.0 3.9 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) PP1_bind PF15276.6 KFP13401.1 - 1.9e-19 69.7 0.4 2.3e-19 69.4 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 binding COE1_HLH PF16423.5 KFP13402.1 - 7e-35 118.5 2.0 5.1e-28 96.5 0.3 2.5 2 0 0 2 2 2 2 Transcription factor COE1 helix-loop-helix domain COE1_DBD PF16422.5 KFP13402.1 - 1.6e-33 116.1 1.0 2.1e-33 115.7 1.0 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain TIG PF01833.24 KFP13402.1 - 4.8e-12 45.8 0.1 4.8e-12 45.8 0.1 2.3 3 0 0 3 3 3 1 IPT/TIG domain Pericardin_rpt PF07054.11 KFP13402.1 - 0.2 11.8 1.8 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 Pericardin like repeat WD40 PF00400.32 KFP13403.1 - 1.5e-10 41.5 1.7 2.8 9.0 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13403.1 - 1.9e-05 24.8 0.1 1.5 9.2 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFP13403.1 - 0.038 13.6 0.5 1.2 8.7 0.1 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family BNIP3 PF06553.12 KFP13404.1 - 8.1e-84 280.2 1.9 9e-84 280.0 1.9 1.0 1 0 0 1 1 1 1 BNIP3 Amidohydro_1 PF01979.20 KFP13405.1 - 4.3e-51 174.3 0.1 5.4e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP13405.1 - 1.9e-12 47.4 0.6 1.6e-07 31.2 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family 7tm_1 PF00001.21 KFP13406.1 - 5.6e-81 271.7 4.6 6.5e-81 271.5 4.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP13406.1 - 4.2e-19 68.9 3.3 5.6e-19 68.5 3.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP13406.1 - 1.2e-09 38.2 9.7 2.4e-09 37.2 9.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP13406.1 - 4e-07 29.7 1.0 4e-07 29.7 1.0 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP13406.1 - 0.00019 21.3 5.3 0.003 17.3 4.3 2.3 2 0 0 2 2 2 1 Olfactory receptor DUF4462 PF14692.6 KFP13407.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) LRR_8 PF13855.6 KFP13411.1 - 1.1e-53 178.8 45.9 8.1e-15 54.3 1.2 5.6 2 2 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 KFP13411.1 - 8.3e-21 74.3 1.5 1.2e-09 38.2 0.0 2.6 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP13411.1 - 2.9e-20 72.0 39.0 1.8e-06 28.2 5.9 6.6 2 2 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP13411.1 - 7.8e-13 48.3 8.3 2.4e-05 23.9 0.3 3.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP13411.1 - 1.8e-11 42.9 34.5 0.46 11.2 0.1 10.6 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 KFP13411.1 - 0.00021 21.1 33.2 0.92 9.7 0.6 8.6 9 0 0 9 9 9 4 Leucine Rich repeat LRRNT PF01462.18 KFP13411.1 - 0.025 14.2 3.7 0.04 13.6 1.9 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LSR PF05624.14 KFP13411.1 - 7.9 6.6 7.0 0.55 10.3 1.5 1.9 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) DUF4462 PF14692.6 KFP13414.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) SPACA7 PF15307.6 KFP13417.1 - 0.027 14.7 0.7 0.042 14.1 0.1 1.5 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Y_phosphatase PF00102.27 KFP13420.1 - 5.8e-74 248.6 0.2 8.3e-74 248.1 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP13420.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DnaJ PF00226.31 KFP13421.1 - 8.4e-29 99.5 4.6 1.4e-28 98.8 4.6 1.4 1 0 0 1 1 1 1 DnaJ domain HECT PF00632.25 KFP13422.1 - 2e-96 323.1 0.0 3.5e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFP13422.1 - 0.00036 20.1 0.1 0.00096 18.7 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif MA3 PF02847.17 KFP13423.1 - 2.3e-26 92.0 1.4 2.3e-26 92.0 1.4 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KFP13423.1 - 2.4e-21 76.4 6.4 2.4e-21 76.4 6.4 2.2 2 0 0 2 2 2 1 MIF4G domain CDC45 PF02724.14 KFP13423.1 - 2.5 6.3 9.6 4.7 5.4 9.6 1.4 1 0 0 1 1 1 0 CDC45-like protein LMBR1 PF04791.16 KFP13425.1 - 7.8e-91 305.5 27.0 1.7e-55 188.9 13.7 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein Orf78 PF06024.12 KFP13425.1 - 0.026 14.8 0.3 0.026 14.8 0.3 3.6 4 0 0 4 4 4 0 Orf78 (ac78) Sigma_reg_N PF13800.6 KFP13425.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.5 5 1 0 5 5 5 0 Sigma factor regulator N-terminal zf-RING_2 PF13639.6 KFP13426.1 - 9.8e-15 54.6 23.5 1.3e-08 35.0 5.5 3.4 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KFP13426.1 - 8.2e-12 44.9 23.6 8.5e-07 28.8 6.2 3.0 2 1 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.7 KFP13426.1 - 2.4e-11 43.7 21.5 2.3e-05 24.6 6.7 3.3 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP13426.1 - 2.4e-10 40.3 18.8 7.8e-08 32.2 0.8 3.9 2 2 1 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP13426.1 - 1.3e-09 37.8 19.8 3.2e-06 26.9 6.0 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP13426.1 - 1.8e-09 37.2 17.3 1.3e-05 24.8 3.8 3.7 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFP13426.1 - 2e-09 37.2 17.3 4.3e-05 23.3 4.6 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP13426.1 - 3.9e-09 36.4 13.9 0.00028 20.9 3.7 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFP13426.1 - 1.9e-08 34.0 17.3 0.00013 21.7 4.0 3.6 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 IQ PF00612.27 KFP13426.1 - 1.8e-06 27.3 3.8 6.9e-06 25.4 3.8 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4_2 PF13923.6 KFP13426.1 - 2e-06 27.5 24.4 7.5e-05 22.5 7.0 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFP13426.1 - 0.009 15.6 2.9 0.009 15.6 2.9 3.0 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFP13426.1 - 0.024 14.4 14.6 0.38 10.6 0.8 3.2 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Pellino PF04710.14 KFP13426.1 - 0.049 12.3 5.1 0.096 11.3 0.5 2.2 2 0 0 2 2 2 0 Pellino Zn_Tnp_IS1595 PF12760.7 KFP13426.1 - 0.086 12.8 0.3 0.086 12.8 0.3 3.1 3 0 0 3 3 2 0 Transposase zinc-ribbon domain DUF5318 PF17249.2 KFP13426.1 - 0.34 10.7 3.3 2.6 7.8 0.3 3.3 2 1 2 4 4 4 0 Family of unknown function (DUF5318) zf-C3HC4_4 PF15227.6 KFP13426.1 - 1.8 8.8 24.4 0.22 11.7 1.8 3.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KFP13426.1 - 1.9 8.4 21.3 0.45 10.4 4.5 4.0 3 1 1 4 4 4 0 PHD-finger zf-RING-like PF08746.11 KFP13426.1 - 5.1 7.5 18.1 0.47 10.8 4.5 3.1 3 0 0 3 3 2 0 RING-like domain Zf_RING PF16744.5 KFP13426.1 - 6 7.1 15.4 1.4 9.1 3.5 4.0 2 2 1 3 3 3 0 KIAA1045 RING finger LRR_8 PF13855.6 KFP13429.1 - 2.4e-50 168.1 37.7 4.4e-16 58.4 5.1 6.6 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFP13429.1 - 9e-23 80.0 44.5 3.7e-06 27.2 0.6 8.0 5 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP13429.1 - 5.6e-17 61.9 0.4 3.3e-08 33.5 0.8 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP13429.1 - 1.1e-08 34.8 15.5 0.00014 21.4 0.3 4.4 2 2 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KFP13429.1 - 0.00032 20.8 37.0 0.19 12.4 0.0 10.6 10 2 0 10 10 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFP13429.1 - 0.00044 19.8 3.3 0.00044 19.8 3.3 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain TPKR_C2 PF16920.5 KFP13429.1 - 0.004 17.2 0.4 0.54 10.4 0.1 3.0 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain SOXp PF12336.8 KFP13431.1 - 1.5e-34 118.9 2.2 1.5e-34 118.9 2.2 2.4 2 0 0 2 2 2 1 SOX transcription factor HMG_box PF00505.19 KFP13431.1 - 1.1e-27 96.2 3.2 1.9e-27 95.5 2.4 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP13431.1 - 1.5e-11 44.7 2.0 2.4e-11 44.1 2.0 1.3 1 0 0 1 1 1 1 HMG-box domain Neur_chan_memb PF02932.16 KFP13432.1 - 1.2e-52 179.3 0.0 2e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP13432.1 - 1.3e-36 126.1 0.1 1.8e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFP13433.1 - 9.1e-48 162.6 0.0 1.4e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP13433.1 - 4e-38 131.8 7.3 2e-31 109.9 5.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFP13433.1 - 0.059 12.4 1.6 0.078 12.0 1.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Neur_chan_LBD PF02931.23 KFP13434.1 - 7.5e-37 126.9 1.6 1.1e-36 126.3 1.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP13434.1 - 4.7e-36 125.0 10.7 1e-32 114.1 5.4 2.1 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ion_trans PF00520.31 KFP13435.1 - 3e-28 98.7 8.1 5.2e-28 97.9 8.1 1.4 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFP13435.1 - 2.7e-26 91.7 6.9 6.6e-26 90.5 6.9 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFP13435.1 - 6.6e-19 67.8 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP13435.1 - 0.05 13.6 7.1 0.16 11.9 7.1 2.0 1 1 0 1 1 1 0 Ion channel Miff PF05644.11 KFP13436.1 - 3.4e-17 63.0 0.1 4e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Gla PF00594.20 KFP13437.1 - 5.7e-20 71.2 9.9 1.3e-19 70.1 9.9 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain T2SSM PF04612.12 KFP13437.1 - 0.054 13.5 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TMEM52 PF14979.6 KFP13437.1 - 1.1 9.1 6.5 31 4.5 0.6 3.2 2 1 1 3 3 3 0 Transmembrane 52 SIT PF15330.6 KFP13437.1 - 5.2 7.6 5.0 2.8 8.4 0.2 2.7 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT SKG6 PF08693.10 KFP13437.1 - 8.7 5.8 9.8 17 4.9 9.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PMP22_Claudin PF00822.20 KFP13438.1 - 7.2e-24 84.5 6.4 8.8e-24 84.2 6.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP13438.1 - 1.1e-07 31.8 7.4 2.7e-07 30.6 7.3 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP13438.1 - 0.0087 15.9 5.4 0.0097 15.8 4.9 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF872 PF05915.12 KFP13438.1 - 0.043 14.0 0.3 0.043 14.0 0.3 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DuoxA PF10204.9 KFP13438.1 - 0.14 11.2 1.5 0.14 11.1 0.6 1.5 1 1 0 1 1 1 0 Dual oxidase maturation factor OppC_N PF12911.7 KFP13438.1 - 0.19 11.8 1.3 3.5 7.7 0.1 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ATP-synt_I PF03899.15 KFP13438.1 - 1.4 9.3 8.5 0.054 13.9 1.3 2.1 2 0 0 2 2 2 0 ATP synthase I chain PLDc_2 PF13091.6 KFP13439.1 - 3.5e-14 52.8 0.0 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFP13439.1 - 0.051 13.8 2.0 2.2 8.6 0.2 2.9 2 1 0 2 2 2 0 Phospholipase D Active site motif Phytoreo_Pns PF05451.11 KFP13439.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 HSF_DNA-bind PF00447.17 KFP13440.1 - 1.7e-26 92.6 1.4 2.5e-26 92.1 1.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Ras PF00071.22 KFP13441.1 - 9.6e-59 197.6 0.0 1.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13441.1 - 8.6e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP13441.1 - 1.1e-09 38.0 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP13441.1 - 1.5e-06 27.9 0.2 8.6e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP13441.1 - 6.4e-06 26.2 0.0 0.046 13.6 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP13441.1 - 1.6e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP13441.1 - 0.0037 16.8 0.0 0.032 13.8 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KFP13441.1 - 0.017 14.5 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 KFP13441.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 Septin G-alpha PF00503.20 KFP13441.1 - 0.028 13.6 0.0 1.3 8.1 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KFP13441.1 - 0.032 14.0 0.5 0.72 9.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFP13441.1 - 0.13 12.5 0.1 2.4 8.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain Ldh_1_N PF00056.23 KFP13441.1 - 0.15 12.2 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AAA_25 PF13481.6 KFP13441.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFP13441.1 - 0.2 12.0 0.1 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Carb_anhydrase PF00194.21 KFP13442.1 - 4.8e-88 295.0 0.0 5.3e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase VPS13 PF16908.5 KFP13442.1 - 0.085 12.6 0.0 15 5.3 0.0 2.5 2 1 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal Carb_anhydrase PF00194.21 KFP13443.1 - 5.8e-91 304.5 0.0 6.4e-91 304.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase LRR_4 PF12799.7 KFP13444.1 - 8.2e-16 57.9 15.1 1.4e-06 28.5 2.1 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP13444.1 - 1.3e-11 44.4 0.5 6.1e-08 32.4 0.4 3.7 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFP13444.1 - 3.3e-09 36.4 20.7 7.5e-07 28.8 4.5 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFP13444.1 - 0.00053 19.8 19.5 0.18 11.9 0.5 4.5 3 1 1 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 KFP13444.1 - 0.13 12.9 14.1 1.1 10.1 0.3 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat SelB-wing_1 PF09105.10 KFP13444.1 - 3.5 7.7 6.7 14 5.8 0.1 3.5 3 0 0 3 3 3 0 Elongation factor SelB, winged helix AA_permease_2 PF13520.6 KFP13445.1 - 2.4e-56 191.4 42.2 2.9e-56 191.1 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP13445.1 - 4e-20 71.9 38.4 5.7e-20 71.4 38.4 1.2 1 0 0 1 1 1 1 Amino acid permease Alpha-2-MRAP_C PF06401.11 KFP13446.1 - 0.013 15.5 3.0 0.018 15.0 3.0 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain IES5 PF17335.2 KFP13446.1 - 0.014 15.6 1.2 0.022 15.0 1.2 1.2 1 0 0 1 1 1 0 Ino80 complex subunit 5 SKA2 PF16740.5 KFP13446.1 - 0.018 14.8 2.5 0.025 14.4 2.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Golgin_A5 PF09787.9 KFP13446.1 - 0.019 14.4 5.0 0.024 14.1 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SR-25 PF10500.9 KFP13446.1 - 0.026 14.1 5.5 0.034 13.8 5.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein XhlA PF10779.9 KFP13446.1 - 0.08 13.2 5.2 0.14 12.4 5.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA RP-C_C PF11800.8 KFP13446.1 - 0.13 12.3 2.5 0.18 11.9 2.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region PA26 PF04636.13 KFP13446.1 - 0.19 10.6 1.9 0.24 10.3 1.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4349 PF14257.6 KFP13446.1 - 0.22 10.9 1.7 0.37 10.2 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 KFP13446.1 - 0.34 10.2 3.0 0.43 9.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIEZO PF15917.5 KFP13446.1 - 0.42 10.1 4.8 0.59 9.6 4.8 1.1 1 0 0 1 1 1 0 Piezo DUF4611 PF15387.6 KFP13446.1 - 6.9 7.0 14.4 0.085 13.1 5.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) SDF PF00375.18 KFP13447.1 - 1.3e-131 439.2 28.4 1.5e-131 439.0 28.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Dicty_CTDC PF00526.18 KFP13448.1 - 0.42 10.6 11.1 7.8 6.5 6.7 2.9 3 1 0 3 3 3 0 Dictyostelium (slime mold) repeat SLBP_RNA_bind PF15247.6 KFP13449.1 - 5.1e-29 100.2 3.3 1.3e-28 98.9 3.3 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Carla_C4 PF01623.17 KFP13449.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein SLBP_RNA_bind PF15247.6 KFP13450.1 - 1e-29 102.5 4.0 2.2e-29 101.4 4.0 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Tmpp129 PF10272.9 KFP13451.1 - 4.8e-118 394.5 7.8 5.4e-118 394.4 7.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor C1_4 PF07975.12 KFP13451.1 - 0.02 15.1 2.2 0.02 15.1 2.2 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3577 PF12101.8 KFP13451.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) SNAD4 PF18750.1 KFP13451.1 - 0.63 10.2 8.3 1.4 9.1 0.1 2.4 1 1 1 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 IBR PF01485.21 KFP13451.1 - 5.6 7.3 18.9 2.3 8.5 0.6 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain TACC_C PF05010.14 KFP13452.1 - 8.4e-91 303.2 41.9 1.7e-90 302.2 41.9 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Il13Ra_Ig PF18001.1 KFP13452.1 - 0.034 14.2 0.7 0.11 12.6 0.7 1.9 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain DUF3584 PF12128.8 KFP13452.1 - 1.1 6.7 28.9 1.7 6.0 28.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 KFP13452.1 - 1.6 9.1 7.4 3.8 7.8 0.7 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ZapD PF07072.11 KFP13452.1 - 8.7 6.0 17.0 0.057 13.2 2.2 3.2 2 1 2 4 4 4 0 Cell division protein MMR_HSR1_Xtn PF16897.5 KFP13453.1 - 5.8e-43 145.2 0.0 1.1e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFP13453.1 - 4.9e-24 84.1 0.0 8.9e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFP13453.1 - 9.4e-20 70.8 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP13453.1 - 6.2e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFP13453.1 - 0.023 14.8 0.3 1.5 8.8 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Vac_ImportDeg PF09783.9 KFP13454.1 - 7.9e-55 185.1 5.0 8.9e-55 184.9 5.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein ATP12 PF07542.11 KFP13455.1 - 1.8e-37 128.3 0.3 2.9e-37 127.6 0.3 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein VHS PF00790.19 KFP13456.1 - 7.6e-45 152.2 0.2 2.2e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KFP13456.1 - 9.9e-28 96.3 2.4 2.5e-27 95.0 2.4 1.7 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 KFP13456.1 - 0.0098 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 ENTH domain HEAT_2 PF13646.6 KFP13456.1 - 0.042 14.3 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats Pap_E4 PF02711.14 KFP13456.1 - 0.11 13.5 0.7 0.31 12.0 0.7 1.7 1 0 0 1 1 1 0 E4 protein FAA_hydrolase PF01557.18 KFP13459.1 - 3.4e-57 193.6 0.0 4.4e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFP13459.1 - 6.8e-33 113.1 0.0 1.1e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal zf-A20 PF01754.16 KFP13460.1 - 8.3e-13 48.0 8.7 2.5e-12 46.5 8.7 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFP13460.1 - 3.3e-09 36.8 7.5 3.3e-09 36.8 7.5 2.3 3 1 1 4 4 4 1 AN1-like Zinc finger IQCJ-SCHIP1 PF15157.6 KFP13460.1 - 4.8 7.0 7.2 0.69 9.7 0.5 2.0 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Bcl-2 PF00452.19 KFP13461.1 - 1.1e-21 77.3 0.0 2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family 5-FTHF_cyc-lig PF01812.20 KFP13462.1 - 3.4e-50 170.5 0.0 3.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family UPF0258 PF06789.12 KFP13463.1 - 2.1e-60 203.3 0.2 4.8e-60 202.1 0.2 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) RXT2_N PF08595.11 KFP13463.1 - 0.0067 16.5 0.4 0.0067 16.5 0.4 2.2 2 0 0 2 2 2 1 RXT2-like, N-terminal Frtz PF11768.8 KFP13464.1 - 0.21 9.8 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PEX11 PF05648.14 KFP13465.1 - 3e-63 213.3 0.5 3.4e-63 213.1 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MCC-bdg_PDZ PF10506.9 KFP13465.1 - 0.0047 16.9 0.2 0.015 15.3 0.2 1.8 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Herpes_UL55 PF04537.12 KFP13465.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein P4Ha_N PF08336.11 KFP13465.1 - 0.044 13.8 0.7 2.2 8.3 0.2 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RhoGEF PF00621.20 KFP13465.1 - 0.053 13.8 0.2 0.093 13.0 0.2 1.4 1 0 0 1 1 1 0 RhoGEF domain Perilipin PF03036.16 KFP13466.1 - 5.2e-55 187.1 0.2 5.8e-55 186.9 0.2 1.0 1 0 0 1 1 1 1 Perilipin family Treslin_N PF15292.6 KFP13468.1 - 1.1e-264 880.6 6.6 1.3e-264 880.4 6.6 1.0 1 0 0 1 1 1 1 Treslin N-terminus Ammonium_transp PF00909.21 KFP13469.1 - 3.3e-74 250.0 20.2 3.7e-74 249.8 20.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4293 PF14126.6 KFP13469.1 - 0.15 12.3 1.6 0.39 11.0 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) FANCI_HD2 PF14680.6 KFP13470.1 - 6.5e-98 326.7 1.9 6.5e-98 326.7 1.9 2.5 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S4 PF14678.6 KFP13470.1 - 6.2e-94 313.8 5.6 6.2e-94 313.8 5.6 3.6 4 0 0 4 4 4 1 FANCI solenoid 4 FANCI_S1 PF14675.6 KFP13470.1 - 8.5e-81 270.8 0.7 4.6e-80 268.4 0.7 2.4 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S3 PF14677.6 KFP13470.1 - 1e-77 260.6 5.8 1e-77 260.6 5.8 3.5 4 0 0 4 4 4 1 FANCI solenoid 3 FANCI_S2 PF14676.6 KFP13470.1 - 9e-61 205.0 3.5 4.9e-60 202.6 0.2 3.5 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_HD1 PF14679.6 KFP13470.1 - 1.2e-31 108.5 0.7 6.8e-31 106.1 0.7 2.5 1 0 0 1 1 1 1 FANCI helical domain 1 F5_F8_type_C PF00754.25 KFP13471.1 - 3.2e-60 201.8 2.3 1.1e-31 109.5 2.7 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.27 KFP13471.1 - 2.4e-21 75.7 46.0 8.3e-09 35.6 8.3 3.8 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KFP13471.1 - 6.6e-12 45.6 31.9 0.0002 21.8 6.6 4.2 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 KFP13471.1 - 2.2e-09 37.5 40.8 0.0022 18.3 8.6 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 KFP13471.1 - 0.51 10.6 34.9 0.27 11.4 9.9 4.1 2 1 1 3 3 3 0 EGF domain EGF_CA PF07645.15 KFP13471.1 - 4.3 7.6 38.8 0.055 13.7 8.8 4.1 1 1 2 3 3 3 0 Calcium-binding EGF domain Abhydrolase_1 PF00561.20 KFP13472.1 - 6.9e-28 98.0 0.0 8.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP13472.1 - 7.8e-11 41.7 0.0 2.5e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 KFP13472.1 - 0.0049 16.9 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Cutinase DUF915 PF06028.11 KFP13472.1 - 0.0057 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2637 PF10935.8 KFP13472.1 - 0.0061 16.5 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2637) Abhydrolase_6 PF12697.7 KFP13472.1 - 0.0073 16.9 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFP13472.1 - 0.0082 15.6 0.2 0.56 9.6 0.1 2.8 2 1 1 3 3 3 1 Prolyl oligopeptidase family VirJ PF06057.11 KFP13472.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF5464 PF17552.2 KFP13472.1 - 0.14 12.5 1.2 1.1 9.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5464) Lipase_3 PF01764.25 KFP13472.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KFP13472.1 - 0.18 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Xlink PF00193.17 KFP13473.1 - 5.7e-40 135.6 0.8 2.4e-19 69.5 0.1 3.1 2 1 1 3 3 3 2 Extracellular link domain V-set PF07686.17 KFP13473.1 - 1.4e-12 47.7 0.1 3.1e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFP13473.1 - 1.9e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP13473.1 - 5.2e-06 27.0 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP13473.1 - 0.00028 20.9 0.0 0.00064 19.7 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFP13473.1 - 0.0035 17.4 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFP13473.1 - 0.0076 16.6 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.21 KFP13473.1 - 0.013 16.3 0.1 0.49 11.1 0.1 2.3 2 0 0 2 2 2 0 Lectin C-type domain Xlink PF00193.17 KFP13474.1 - 2.4e-122 399.6 16.1 2e-32 111.4 0.4 5.4 5 1 0 5 5 5 4 Extracellular link domain Lectin_C PF00059.21 KFP13474.1 - 7.2e-22 78.2 15.8 1.3e-19 70.9 2.5 5.1 5 0 0 5 5 5 2 Lectin C-type domain Sushi PF00084.20 KFP13474.1 - 2.3e-09 37.7 1.7 6.8e-09 36.2 1.7 1.9 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) V-set PF07686.17 KFP13474.1 - 2.9e-09 37.1 0.0 6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain CTD PF12815.7 KFP13474.1 - 3.9e-08 33.7 23.7 0.33 11.5 2.0 7.0 1 1 5 6 6 6 6 Spt5 C-terminal nonapeptide repeat binding Spt4 EGF PF00008.27 KFP13474.1 - 6.8e-06 26.3 4.0 2.5e-05 24.5 4.0 2.1 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP13474.1 - 3.7e-05 24.2 1.4 3.7e-05 24.2 1.4 3.0 4 0 0 4 4 4 1 Human growth factor-like EGF Chordopox_A33R PF05966.12 KFP13474.1 - 0.037 13.3 2.1 8.1 5.7 0.1 3.9 4 0 0 4 4 4 0 Chordopoxvirus A33R protein Pentapeptide_4 PF13599.6 KFP13474.1 - 0.072 13.3 0.0 7.9 6.7 0.0 3.9 3 2 1 4 4 4 0 Pentapeptide repeats (9 copies) EGF_CA PF07645.15 KFP13474.1 - 0.086 13.1 8.9 0.17 12.1 7.3 2.5 2 1 0 2 2 2 0 Calcium-binding EGF domain RNase_T PF00929.24 KFP13475.1 - 4.4e-18 66.4 0.0 5.7e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFP13475.1 - 3.3e-05 23.7 0.0 9.4e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Det1 PF09737.9 KFP13476.1 - 7.8e-196 651.0 0.7 9.3e-196 650.8 0.7 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 Ribosomal_S11 PF00411.19 KFP13477.1 - 6.7e-28 97.3 2.5 7.7e-28 97.1 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 MRP-L46 PF11788.8 KFP13478.1 - 0.00022 22.0 1.6 0.00041 21.1 1.6 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KFP13478.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.5 2 0 0 2 2 2 0 NUDIX domain TATR PF03430.13 KFP13478.1 - 0.17 10.2 0.1 0.24 9.7 0.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Kelch_5 PF13854.6 KFP13479.1 - 1.5e-26 91.9 19.1 4.7e-08 32.9 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP13479.1 - 2.3e-20 72.3 7.3 2.2e-05 24.4 0.2 6.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFP13479.1 - 3.5e-20 71.3 15.7 4.8e-05 22.9 0.2 6.6 7 0 0 7 7 7 5 Kelch motif PSI PF01437.25 KFP13479.1 - 4.4e-18 65.6 54.0 1e-12 48.4 9.6 8.3 7 1 0 7 7 6 5 Plexin repeat Kelch_6 PF13964.6 KFP13479.1 - 1.9e-17 62.9 14.4 2.2e-05 24.6 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Lectin_C PF00059.21 KFP13479.1 - 8.6e-16 58.6 0.1 8.6e-16 58.6 0.1 3.3 3 1 0 3 3 1 1 Lectin C-type domain Kelch_3 PF13415.6 KFP13479.1 - 4.8e-13 49.0 10.2 0.00053 20.2 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP13479.1 - 4.1e-12 45.6 8.1 0.013 15.5 0.0 5.6 5 0 0 5 5 5 3 Kelch motif CUB PF00431.20 KFP13479.1 - 2.5e-11 43.9 0.0 7.4e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.13 KFP13479.1 - 9.3e-05 22.7 10.2 9.3e-05 22.7 10.2 8.6 5 2 0 5 5 2 2 EGF-like domain Laminin_EGF PF00053.24 KFP13479.1 - 0.00011 22.3 18.3 0.00011 22.3 18.3 8.4 5 3 2 7 7 4 2 Laminin EGF domain PSI_integrin PF17205.3 KFP13479.1 - 0.0014 18.3 7.7 0.0014 18.3 7.7 6.6 7 0 0 7 7 4 2 Integrin plexin domain TMEM100 PF16311.5 KFP13479.1 - 0.043 13.4 0.6 0.084 12.5 0.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 TruB_N PF01509.18 KFP13480.1 - 1.4e-30 106.6 0.0 2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFP13480.1 - 3.3e-08 33.6 0.0 6.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DMA PF03474.14 KFP13480.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif RAI16-like PF10257.9 KFP13481.1 - 3.9e-140 466.8 3.8 5.1e-140 466.4 3.8 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein AbLIM_anchor PF16182.5 KFP13482.1 - 2.3e-117 393.0 22.1 1.1e-87 295.3 19.7 2.6 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFP13482.1 - 1.4e-44 150.1 42.3 7e-15 55.0 1.7 5.0 4 1 1 5 5 5 4 LIM domain VHP PF02209.19 KFP13482.1 - 1.3e-15 57.1 1.2 2.2e-15 56.4 0.6 1.7 2 0 0 2 2 2 1 Villin headpiece domain PH PF00169.29 KFP13483.1 - 8.7e-22 77.6 2.3 1.2e-09 38.6 0.1 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP13483.1 - 2.1e-08 34.5 3.2 0.0031 17.9 0.1 3.8 3 1 0 3 3 3 2 Pleckstrin homology domain MctB PF11382.8 KFP13483.1 - 0.24 11.0 1.9 0.47 10.1 1.9 1.4 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB UPF0242 PF06785.11 KFP13483.1 - 0.38 10.8 6.7 1.2 9.2 6.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KFP13483.1 - 0.64 10.0 15.2 4.9 7.1 2.5 3.1 2 0 0 2 2 2 0 Prefoldin subunit ATP-synt_B PF00430.18 KFP13483.1 - 0.65 10.1 8.1 0.17 12.0 0.2 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) VWA PF00092.28 KFP13484.1 - 2.2e-92 308.1 0.0 1.2e-35 123.3 0.0 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.6 KFP13484.1 - 1.8e-35 121.8 0.0 1.1e-13 51.8 0.0 3.5 3 0 0 3 3 3 3 von Willebrand factor type A domain EGF PF00008.27 KFP13484.1 - 4.2e-13 49.3 24.9 3.8e-07 30.3 9.2 2.7 2 0 0 2 2 2 2 EGF-like domain VWA_3 PF13768.6 KFP13484.1 - 3.3e-09 36.9 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain hEGF PF12661.7 KFP13484.1 - 2e-07 31.4 18.2 0.00017 22.1 5.3 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF TUDOR PF00567.24 KFP13485.1 - 1.6e-122 402.7 4.8 3e-34 117.7 0.0 4.4 4 0 0 4 4 4 4 Tudor domain SMN PF06003.12 KFP13485.1 - 6.1e-19 68.3 0.1 2.1e-05 23.9 0.0 4.2 4 0 0 4 4 4 4 Survival motor neuron protein (SMN) zf-MYND PF01753.18 KFP13485.1 - 4.5e-10 39.5 14.6 4.5e-10 39.5 14.6 2.6 2 0 0 2 2 2 1 MYND finger Agenet PF05641.12 KFP13485.1 - 1.6e-08 34.9 1.4 0.99 9.9 0.0 5.3 5 0 0 5 5 5 3 Agenet domain DUF4537 PF15057.6 KFP13485.1 - 4.4e-07 29.9 0.0 2.2 8.3 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4537) TDRP PF15683.5 KFP13485.1 - 0.01 15.8 1.3 0.013 15.4 0.1 1.7 2 0 0 2 2 2 0 Testis development-related protein 7TMR-DISMED2 PF07696.11 KFP13485.1 - 0.02 15.0 0.0 0.86 9.7 0.0 2.6 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 PCB_OB PF17092.5 KFP13485.1 - 0.1 13.3 0.0 4.5 8.1 0.0 2.9 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain Tudor_4 PF18358.1 KFP13485.1 - 0.3 10.7 3.0 3.1 7.5 0.0 3.5 4 0 0 4 4 4 0 Histone methyltransferase Tudor domain zf-HIT PF04438.16 KFP13485.1 - 3.5 7.6 14.4 0.28 11.1 8.3 2.5 2 0 0 2 2 2 0 HIT zinc finger Nebulin PF00880.18 KFP13487.1 - 5.3e-217 700.2 162.1 2.6e-09 36.8 0.5 43.5 44 0 0 44 44 44 42 Nebulin repeat LIM PF00412.22 KFP13487.1 - 5.8e-10 39.3 9.4 1.5e-09 38.0 9.4 1.7 1 0 0 1 1 1 1 LIM domain c-SKI_SMAD_bind PF08782.10 KFP13487.1 - 0.048 13.9 1.1 0.2 11.9 1.1 2.1 1 0 0 1 1 1 0 c-SKI Smad4 binding domain DUF1510 PF07423.11 KFP13487.1 - 0.36 11.0 5.7 19 5.5 0.2 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1510) ArfA PF03889.13 KFP13487.1 - 0.64 9.6 4.9 35 4.0 0.0 4.6 5 0 0 5 5 5 0 Alternative ribosome-rescue factor A Trypsin PF00089.26 KFP13488.1 - 4.3e-62 209.8 0.1 5.8e-62 209.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP13488.1 - 2.7e-21 75.6 3.5 2.7e-21 75.6 3.5 2.3 2 0 0 2 2 2 1 Kringle domain EGF PF00008.27 KFP13488.1 - 3.4e-14 52.8 23.4 2.4e-08 34.1 6.8 4.8 5 0 0 5 5 5 2 EGF-like domain hEGF PF12661.7 KFP13488.1 - 0.0025 18.4 14.5 0.0078 16.8 4.3 5.2 6 0 0 6 6 6 2 Human growth factor-like EGF Trypsin_2 PF13365.6 KFP13488.1 - 0.0083 17.0 0.0 0.017 16.0 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP13488.1 - 0.024 15.0 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) EGF_2 PF07974.13 KFP13488.1 - 0.74 10.2 35.6 0.078 13.4 10.1 4.6 4 0 0 4 4 4 0 EGF-like domain Cadherin PF00028.17 KFP13491.1 - 3.1e-85 280.8 1.9 8.5e-18 64.6 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP13491.1 - 4.6e-18 66.0 0.2 1.2e-17 64.6 0.2 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_4 PF17803.1 KFP13491.1 - 2e-08 34.7 10.9 0.0011 19.5 0.1 4.1 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KFP13491.1 - 6.4e-06 25.9 0.0 0.65 9.9 0.0 3.9 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFP13491.1 - 6e-05 23.0 5.0 2.1 8.4 0.1 5.1 5 0 0 5 5 5 1 Cadherin-like Big_9 PF17963.1 KFP13491.1 - 0.014 16.1 11.5 2 9.2 0.2 4.2 3 1 0 3 3 3 0 Bacterial Ig domain Cadherin_pro PF08758.11 KFP13491.1 - 0.026 14.7 0.0 3.6 7.8 0.0 2.8 2 0 0 2 2 2 0 Cadherin prodomain like Invasin_D3 PF09134.10 KFP13491.1 - 0.11 12.8 0.8 3.9 7.8 0.0 3.4 3 1 0 3 3 3 0 Invasin, domain 3 DUF5527 PF17665.1 KFP13491.1 - 0.54 9.8 2.2 1 8.9 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Cadherin PF00028.17 KFP13497.1 - 7.1e-83 273.2 4.1 5e-19 68.5 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP13497.1 - 1.9e-57 193.7 0.1 3.5e-57 192.8 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP13497.1 - 1.5e-07 31.4 4.2 1.2 9.2 0.0 5.7 6 0 0 6 6 6 2 Cadherin-like Cadherin_2 PF08266.12 KFP13497.1 - 4e-05 23.4 0.0 0.066 13.1 0.0 3.6 3 0 0 3 3 3 1 Cadherin-like Cadherin_pro PF08758.11 KFP13497.1 - 0.00079 19.5 0.0 0.56 10.4 0.0 3.4 3 0 0 3 3 3 1 Cadherin prodomain like DUF4286 PF14114.6 KFP13497.1 - 0.019 15.4 0.0 0.071 13.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) ASFV_J13L PF05568.11 KFP13497.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Invasin_D3 PF09134.10 KFP13497.1 - 0.047 14.0 2.8 15 6.0 0.0 4.6 4 1 1 5 5 5 0 Invasin, domain 3 Cadherin_4 PF17803.1 KFP13497.1 - 0.65 10.7 14.6 3.8 8.2 0.2 4.6 5 0 0 5 5 5 0 Bacterial cadherin-like domain Big_9 PF17963.1 KFP13497.1 - 2.6 8.9 10.4 17 6.2 0.1 4.4 5 0 0 5 5 5 0 Bacterial Ig domain DUF4462 PF14692.6 KFP13498.1 - 0.068 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Herpes_UL56 PF04534.12 KFP13502.1 - 0.017 14.6 0.2 0.017 14.6 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus UL56 protein CYYR1 PF10873.8 KFP13502.1 - 0.58 10.6 4.4 1.7 9.1 1.1 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 dNK PF01712.19 KFP13504.1 - 1.8e-25 90.0 1.3 2.1e-25 89.8 1.3 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFP13504.1 - 0.00054 20.5 0.0 0.00074 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP13504.1 - 0.00077 19.6 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFP13504.1 - 0.0012 18.5 0.1 0.002 17.9 0.1 1.3 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.6 KFP13504.1 - 0.0055 17.1 0.1 0.0099 16.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain MARVEL PF01284.23 KFP13505.1 - 6.5e-10 39.2 14.0 1e-09 38.5 14.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain PNTB_4TM PF12769.7 KFP13505.1 - 0.018 15.5 0.2 0.024 15.1 0.2 1.2 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch MARVEL PF01284.23 KFP13506.1 - 7e-14 52.1 14.8 1e-13 51.5 14.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain YfhO PF09586.10 KFP13506.1 - 0.00052 18.4 0.6 0.00059 18.2 0.6 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO YIF1 PF03878.15 KFP13506.1 - 0.24 10.9 5.0 0.42 10.1 4.9 1.3 1 1 0 1 1 1 0 YIF1 DUF373 PF04123.13 KFP13506.1 - 0.64 9.4 3.9 2 7.8 4.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DLIC PF05783.11 KFP13507.1 - 8.3e-254 842.6 0.0 9.5e-254 842.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KFP13507.1 - 0.0019 18.7 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 KFP13507.1 - 0.0094 16.2 0.2 0.043 14.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFP13507.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFP13507.1 - 0.027 14.2 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP13507.1 - 0.034 14.0 0.3 8.8 6.2 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KFP13507.1 - 0.035 14.5 0.1 0.073 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KFP13507.1 - 0.039 13.4 0.2 0.46 9.9 0.0 2.4 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_22 PF13401.6 KFP13507.1 - 0.04 14.2 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFP13507.1 - 0.046 13.5 0.1 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KFP13507.1 - 0.049 13.4 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KFP13507.1 - 0.051 13.1 0.3 9.3 5.7 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Kinesin PF00225.23 KFP13507.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain ATPase PF06745.13 KFP13507.1 - 0.14 11.5 0.2 0.24 10.7 0.2 1.5 1 1 0 1 1 1 0 KaiC G-alpha PF00503.20 KFP13507.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.6 KFP13507.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFP13507.1 - 0.27 10.8 1.0 0.74 9.4 0.4 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Atx10homo_assoc PF09759.9 KFP13509.1 - 0.00019 21.4 7.4 0.0029 17.6 0.5 3.9 3 2 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Drf_GBD PF06371.13 KFP13509.1 - 0.022 14.3 0.6 0.022 14.3 0.6 2.7 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain ThiF PF00899.21 KFP13510.1 - 1e-20 74.2 0.0 3e-20 72.6 0.0 1.8 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KFP13510.1 - 0.0001 22.4 0.0 0.069 13.4 0.0 3.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle Transket_pyr PF02779.24 KFP13510.1 - 0.057 13.1 1.2 0.1 12.2 0.5 1.7 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain UPF0270 PF06794.12 KFP13510.1 - 0.15 12.1 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Carb_anhydrase PF00194.21 KFP13511.1 - 3.8e-99 331.3 0.0 4.3e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.22 KFP13513.1 - 1e-26 93.5 0.1 1.4e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13513.1 - 0.00094 19.4 0.1 0.0019 18.4 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFP13513.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KFP13513.1 - 0.013 15.0 0.2 0.017 14.6 0.2 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family HA1 PF18239.1 KFP13513.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Hemagglutinin I FeS_assembly_P PF01883.19 KFP13515.1 - 1.2e-14 54.3 0.1 2.7e-14 53.1 0.0 1.6 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein COesterase PF00135.28 KFP13516.1 - 5.6e-144 480.8 0.0 9.8e-107 357.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP13516.1 - 1.3e-08 35.0 0.3 4.6e-08 33.2 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFP13516.1 - 0.055 13.1 0.5 0.36 10.4 0.5 2.0 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.28 KFP13517.1 - 3.8e-168 560.5 0.0 4.3e-168 560.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP13517.1 - 8.9e-10 38.8 2.1 4.3e-09 36.5 2.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP13517.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFP13517.1 - 0.025 14.2 0.8 0.068 12.8 0.8 1.5 1 1 0 1 1 1 0 Putative esterase PDCD2_C PF04194.13 KFP13519.1 - 2.6e-47 161.1 0.3 3.5e-47 160.7 0.3 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Hydrophobin_2 PF06766.11 KFP13519.1 - 0.09 12.7 2.1 0.17 11.8 2.1 1.4 1 0 0 1 1 1 0 Fungal hydrophobin ThiF PF00899.21 KFP13520.1 - 6.4e-57 192.7 0.1 9.8e-57 192.1 0.1 1.3 1 0 0 1 1 1 1 ThiF family UBA2_C PF16195.5 KFP13520.1 - 4.9e-26 91.3 12.8 4.9e-26 91.3 12.8 2.2 3 0 0 3 3 3 1 SUMO-activating enzyme subunit 2 C-terminus UAE_UbL PF14732.6 KFP13520.1 - 3.9e-23 81.9 1.1 1.1e-22 80.4 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFP13520.1 - 1.1e-06 28.8 7.5 0.002 18.1 0.5 2.7 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site LIM PF00412.22 KFP13521.1 - 5e-36 122.7 36.5 4e-14 52.6 8.4 3.1 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.16 KFP13521.1 - 9 6.4 20.1 0.072 13.2 2.0 3.2 1 1 3 4 4 4 0 Mut7-C RNAse domain PGI PF00342.19 KFP13522.1 - 6.1e-262 869.4 0.0 6.9e-262 869.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 KFP13522.1 - 0.012 16.1 0.1 0.045 14.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) TINF2_N PF14973.6 KFP13523.1 - 0.047 14.0 0.0 0.069 13.5 0.0 1.3 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF4745 PF15923.5 KFP13524.1 - 2.3e-48 163.5 1.6 6.2e-48 162.2 1.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4745) Myf5 PF12232.8 KFP13524.1 - 0.027 15.2 1.1 0.027 15.2 1.1 4.0 4 0 0 4 4 4 0 Myogenic determination factor 5 Rapsyn_N PF10579.9 KFP13524.1 - 5.7 7.1 0.0 5.7 7.1 0.0 3.2 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region LSM14 PF12701.7 KFP13525.1 - 1.5e-33 114.7 0.0 2.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFP13525.1 - 4.8e-31 107.7 11.2 5e-31 107.7 7.8 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KFP13525.1 - 5.5e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 KFP13525.1 - 1.7 9.4 21.5 11 6.8 0.4 2.6 2 0 0 2 2 2 0 Glycine rich protein family TAF4 PF05236.14 KFP13526.1 - 3.7e-77 259.8 6.9 4.2e-77 259.6 6.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.17 KFP13526.1 - 8e-05 22.7 0.9 0.33 11.2 0.1 2.6 2 0 0 2 2 2 2 TATA box binding protein associated factor (TAF) Presenilin PF01080.17 KFP13526.1 - 0.027 13.2 1.4 0.035 12.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1955 PF09205.10 KFP13526.1 - 0.13 12.0 0.3 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) BTB_2 PF02214.22 KFP13527.1 - 9.5e-17 61.1 0.1 1.5e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfotransfer_2 PF03567.14 KFP13528.1 - 1.2e-56 192.4 3.9 1.5e-56 192.2 3.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_M24 PF00557.24 KFP13531.1 - 9.3e-63 211.7 0.0 1.6e-59 201.2 0.0 3.0 3 0 0 3 3 3 2 Metallopeptidase family M24 AMP_N PF05195.16 KFP13531.1 - 3.1e-28 98.0 0.0 7.3e-28 96.8 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain bZIP_2 PF07716.15 KFP13532.1 - 1.4e-15 57.1 16.9 1.9e-15 56.7 16.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP13532.1 - 2e-05 24.6 12.4 3.6e-05 23.8 12.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF1319 PF07028.11 KFP13532.1 - 0.016 15.4 1.6 0.023 14.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Jnk-SapK_ap_N PF09744.9 KFP13532.1 - 0.036 14.3 6.5 0.049 13.8 6.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.17 KFP13532.1 - 0.044 14.3 7.7 0.077 13.5 7.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Seryl_tRNA_N PF02403.22 KFP13532.1 - 0.049 13.9 6.9 0.079 13.2 6.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KFP13532.1 - 0.12 12.9 6.9 0.18 12.3 6.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 KFP13532.1 - 0.2 11.9 6.4 0.19 12.0 5.2 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF4094 PF13334.6 KFP13532.1 - 0.34 11.3 3.2 0.52 10.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DivIC PF04977.15 KFP13532.1 - 0.38 10.6 7.7 0.38 10.5 6.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Tho2 PF11262.8 KFP13532.1 - 0.93 8.6 6.0 1.1 8.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LAM_C PF12544.8 KFP13532.1 - 1.8 8.7 6.6 11 6.1 6.6 2.2 1 1 0 1 1 1 0 Lysine-2,3-aminomutase AA_permease_2 PF13520.6 KFP13534.1 - 8.9e-61 206.0 41.6 1.1e-60 205.7 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP13534.1 - 7e-33 113.9 36.1 8.6e-33 113.6 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease p53-inducible11 PF14936.6 KFP13534.1 - 0.25 11.4 10.5 2.2 8.3 2.1 2.5 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF5408 PF17402.2 KFP13534.1 - 0.49 10.3 3.7 1.5 8.8 3.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5408) WD40 PF00400.32 KFP13535.1 - 7.5e-38 127.9 26.4 1.4e-07 32.1 0.5 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13535.1 - 2.7e-08 34.0 0.6 0.078 13.3 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KFP13535.1 - 2.4e-07 29.6 0.1 2.6e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 KFP13535.1 - 5.3e-07 28.7 5.0 0.043 12.5 0.1 4.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP13535.1 - 8.9e-07 28.2 1.2 0.005 15.8 0.5 3.4 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KFP13535.1 - 3.8e-05 24.0 0.0 0.43 11.1 0.0 3.4 4 0 0 4 4 4 2 PQQ-like domain eIF2A PF08662.11 KFP13535.1 - 6.1e-05 23.0 1.1 0.0062 16.4 0.2 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KFP13535.1 - 9.1e-05 22.1 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KFP13535.1 - 0.00016 21.4 0.1 0.0077 16.1 0.1 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat Frtz PF11768.8 KFP13535.1 - 0.028 12.7 0.6 0.59 8.4 0.2 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KFP13535.1 - 0.035 12.9 0.6 0.16 10.6 0.2 2.2 1 1 0 2 2 2 0 Nup133 N terminal like DUF1604 PF07713.13 KFP13536.1 - 4.2e-35 119.4 0.3 4.2e-35 119.4 0.3 4.7 6 0 0 6 6 6 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFP13536.1 - 2.7e-07 30.4 0.1 1e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP13536.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 3.4 3 1 0 3 3 3 1 G-patch domain BRO1 PF03097.18 KFP13537.1 - 7.8e-95 317.9 0.1 9.4e-95 317.7 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 KFP13537.1 - 1.5e-13 50.6 4.0 1.5e-13 50.6 4.0 2.4 2 0 0 2 2 2 1 Hr1 repeat PDZ_6 PF17820.1 KFP13537.1 - 3.4e-06 26.8 0.0 9.2e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP13537.1 - 6.6e-06 26.4 0.0 2.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain MutL_C PF08676.11 KFP13537.1 - 0.062 13.1 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 MutL C terminal dimerisation domain TLV_coat PF00429.19 KFP13538.1 - 0.0002 20.2 0.6 0.0002 20.2 0.6 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) RVT_1 PF00078.27 KFP13539.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP13539.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase ANAPC4_WD40 PF12894.7 KFP13540.1 - 1.2e-08 35.1 3.0 0.47 10.8 0.0 6.7 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KFP13540.1 - 0.00087 19.1 0.3 1.4 9.0 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat WD40 PF00400.32 KFP13540.1 - 0.0045 17.8 9.3 7.1 7.7 0.2 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KFP13540.1 - 0.0063 15.8 0.0 0.05 12.9 0.0 2.5 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 KFP13540.1 - 0.092 12.3 0.3 1.1 8.7 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Pkinase_Tyr PF07714.17 KFP13541.1 - 3.5e-105 351.0 0.0 4.7e-105 350.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP13541.1 - 3.9e-45 154.3 0.0 1e-44 152.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain I-set PF07679.16 KFP13541.1 - 2.5e-37 126.8 0.0 3.5e-14 52.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13541.1 - 8e-36 122.5 0.2 1.2e-11 45.0 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP13541.1 - 1.8e-26 92.3 0.3 2.3e-10 40.6 0.2 3.7 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP13541.1 - 1.6e-24 85.9 0.1 6.1e-08 32.7 0.1 4.0 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KFP13541.1 - 1.5e-15 57.3 2.8 0.00029 21.0 0.0 5.8 4 2 1 5 5 5 3 Immunoglobulin V-set domain FGFR3_TM PF18123.1 KFP13541.1 - 4.4e-15 54.9 2.1 4.4e-15 54.9 2.1 1.9 2 0 0 2 2 2 1 Fibroblast growth factor receptor 3 transmembrane domain Ig_5 PF16681.5 KFP13541.1 - 5.9e-07 29.8 0.0 0.13 12.6 0.0 3.8 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP13541.1 - 2.4e-05 23.8 0.1 1.8 8.2 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFP13541.1 - 0.00075 19.7 0.0 0.075 13.3 0.0 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP13541.1 - 0.0035 17.4 0.3 0.59 10.2 0.3 3.8 3 1 1 4 4 4 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP13541.1 - 0.0073 16.7 0.1 0.15 12.5 0.1 2.6 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP13541.1 - 0.0092 16.0 0.1 6.2 7.0 0.0 3.4 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain SMP_2 PF10144.9 KFP13541.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Kinase-like PF14531.6 KFP13541.1 - 0.066 12.5 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Spc110_C PF18520.1 KFP13541.1 - 0.19 11.4 0.1 0.39 10.4 0.1 1.5 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain ATE_C PF04377.15 KFP13542.1 - 1.8e-52 177.5 0.3 1.4e-51 174.7 0.2 2.2 2 1 1 3 3 3 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFP13542.1 - 8.1e-14 51.8 4.2 2.1e-13 50.4 4.2 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Nse4_C PF08743.10 KFP13543.1 - 3.1e-17 62.6 1.3 3.8e-17 62.3 0.1 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KFP13543.1 - 1.5e-15 57.0 1.3 3.5e-15 55.9 1.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plant_tran PF04827.14 KFP13543.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein PH PF00169.29 KFP13545.1 - 2.1e-32 111.8 0.2 5.6e-19 68.6 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 KFP13545.1 - 2.9e-12 46.7 0.1 2.1e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP13545.1 - 1.3e-08 35.2 1.7 3.5e-05 24.2 0.6 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFP13545.1 - 1.5e-07 31.8 0.2 0.029 14.7 0.1 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 KFP13545.1 - 1.5e-06 28.3 0.0 0.0024 18.0 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.6 KFP13545.1 - 4.5e-05 23.5 0.9 0.01 16.0 0.2 2.8 2 2 0 2 2 2 1 PH domain PH_6 PF15406.6 KFP13545.1 - 0.01 16.1 0.0 5.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 KFP13545.1 - 0.014 15.2 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Trypsin_2 PF13365.6 KFP13546.1 - 5e-32 111.9 0.1 7.1e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFP13546.1 - 2e-16 60.5 0.0 2.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KFP13546.1 - 5.8e-13 48.5 0.2 8.3e-12 44.8 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFP13546.1 - 5.2e-10 39.5 0.2 1.6e-09 38.0 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP13546.1 - 5.9e-10 39.3 0.3 2.1e-09 37.6 0.3 2.0 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KFP13546.1 - 1.2e-06 27.6 0.7 0.027 13.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KFP13546.1 - 2e-05 23.9 0.1 0.088 12.0 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 DUF150_C PF17384.2 KFP13546.1 - 0.0037 17.4 0.8 0.58 10.3 0.2 2.6 2 0 0 2 2 2 1 RimP C-terminal SH3 domain LSM PF01423.22 KFP13546.1 - 0.0057 16.3 0.5 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 LSM domain GRASP55_65 PF04495.14 KFP13546.1 - 0.019 15.3 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ROF PF07073.12 KFP13546.1 - 0.2 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) Zona_pellucida PF00100.23 KFP13547.1 - 1.1e-09 38.5 0.0 1.2e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFP13548.1 - 1.1e-27 97.4 3.5 1.2e-27 97.3 3.5 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.18 KFP13549.1 - 1.7e-33 115.1 6.8 1.8e-33 115.0 6.8 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP13549.1 - 0.0033 17.9 1.0 0.0046 17.5 1.0 1.5 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain Annexin PF00191.20 KFP13550.1 - 2.1e-79 261.5 10.3 7.2e-25 86.9 0.3 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFP13550.1 - 0.00012 21.9 1.3 1.9 8.4 0.1 3.3 2 1 1 3 3 3 2 Myb DNA-binding like Acetyltransf_11 PF13720.6 KFP13550.1 - 0.0018 18.7 0.7 2.8 8.4 0.0 2.9 3 1 1 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TSLP PF15216.6 KFP13550.1 - 0.06 13.6 0.5 16 5.8 0.0 3.4 3 1 0 3 3 3 0 Thymic stromal lymphopoietin DUF5343 PF17278.2 KFP13550.1 - 0.063 13.4 2.3 0.39 10.8 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5343) Kelch_1 PF01344.25 KFP13551.1 - 9.1e-40 134.0 0.2 3.4e-10 39.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP13551.1 - 1.4e-32 110.8 0.5 1.2e-05 25.4 0.0 6.7 3 2 4 7 7 7 6 Kelch motif BTB PF00651.31 KFP13551.1 - 3e-26 91.8 1.4 3.5e-26 91.6 0.3 1.8 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP13551.1 - 3.3e-25 88.2 2.1 8.8e-25 86.8 0.5 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFP13551.1 - 2.3e-24 85.1 0.0 0.00079 19.7 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP13551.1 - 3.6e-24 84.5 1.6 2.5e-05 24.2 0.0 6.8 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP13551.1 - 1.4e-21 75.6 0.5 0.00083 19.2 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP13551.1 - 5.7e-12 45.3 1.9 0.15 12.1 0.2 6.3 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.8 KFP13551.1 - 0.0024 18.0 1.5 0.03 14.5 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 KFP13551.1 - 0.022 14.9 0.1 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Elongin_A PF06881.11 KFP13552.1 - 0.00074 20.0 1.6 0.00089 19.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 KFP13552.1 - 0.0024 17.7 0.2 0.0086 16.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like Pox_A8 PF04745.12 KFP13552.1 - 0.012 14.7 0.6 0.017 14.2 0.6 1.3 1 0 0 1 1 1 0 VITF-3 subunit protein F-box PF00646.33 KFP13552.1 - 0.033 14.1 0.5 0.17 11.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Nt_Gln_amidase PF09764.9 KFP13553.1 - 7.3e-63 211.5 0.0 8.2e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase AAA PF00004.29 KFP13555.1 - 1.8e-46 157.8 0.0 5.4e-41 140.1 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KFP13555.1 - 9.9e-19 67.2 0.0 2.7e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KFP13555.1 - 1.5e-12 47.1 0.2 3.9e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFP13555.1 - 5.9e-07 30.0 0.0 0.00016 22.1 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KFP13555.1 - 9.5e-07 28.7 0.0 0.00026 20.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 KFP13555.1 - 3.3e-05 24.2 4.6 0.032 14.5 0.1 5.4 4 2 0 5 5 5 1 AAA domain AAA_2 PF07724.14 KFP13555.1 - 3.8e-05 23.9 0.0 0.00016 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 KFP13555.1 - 0.00033 20.6 0.7 0.41 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KFP13555.1 - 0.0014 18.6 0.0 0.11 12.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFP13555.1 - 0.0036 17.9 3.3 0.049 14.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 KFP13555.1 - 0.0049 16.4 0.0 0.32 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFP13555.1 - 0.0072 16.7 0.0 0.034 14.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KFP13555.1 - 0.0081 15.9 0.0 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KFP13555.1 - 0.019 14.3 0.1 0.05 12.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KFP13555.1 - 0.049 13.8 0.2 0.43 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFP13555.1 - 0.057 12.8 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KFP13555.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KFP13555.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFP13555.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.6 2 1 0 2 2 2 0 NACHT domain IMUP PF15761.5 KFP13555.1 - 0.16 12.7 2.2 0.32 11.7 2.2 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein TIP49 PF06068.13 KFP13555.1 - 0.16 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KFP13555.1 - 0.27 11.5 1.2 0.66 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Poxvirus_B22R_N PF13169.6 KFP13555.1 - 0.67 10.5 4.3 1.5 9.4 0.2 2.5 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal Dehydrin PF00257.19 KFP13555.1 - 1.7 9.2 3.1 4 8.0 3.1 1.5 1 0 0 1 1 1 0 Dehydrin SR-25 PF10500.9 KFP13555.1 - 3.3 7.3 10.4 0.069 12.7 3.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Homeodomain PF00046.29 KFP13556.1 - 2.8e-29 100.7 7.8 1.2e-07 31.5 0.0 4.4 4 0 0 4 4 4 4 Homeodomain zf_C2H2_ZHX PF18387.1 KFP13556.1 - 2.9e-24 84.5 3.8 3.9e-24 84.0 0.6 2.4 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain Homez PF11569.8 KFP13556.1 - 1.2e-18 66.3 1.9 7e-12 44.6 0.3 4.3 4 0 0 4 4 4 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP13556.1 - 9.9e-15 54.2 9.0 0.00085 19.2 0.2 4.9 5 0 0 5 5 5 4 Homeobox KN domain zf-C2H2 PF00096.26 KFP13556.1 - 6 7.5 7.1 15 6.3 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Tristanin_u2 PF16638.5 KFP13556.1 - 9.8 7.0 8.8 2.7 8.8 2.6 3.2 3 0 0 3 3 3 0 Unstructured region on methyltransferase between zinc-fingers DUF5588 PF17826.1 KFP13558.1 - 1e-92 310.8 3.3 1.6e-92 310.2 3.3 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5588) TPR_12 PF13424.6 KFP13558.1 - 0.065 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP13558.1 - 0.072 14.0 0.0 25 6.0 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFP13558.1 - 0.43 11.4 1.3 0.65 10.8 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FAM83 PF07894.12 KFP13559.1 - 4.2e-98 328.2 0.0 5.2e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFP13559.1 - 0.0048 16.8 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain Rad60-SLD PF11976.8 KFP13559.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RabGAP-TBC PF00566.18 KFP13560.1 - 1.3e-09 38.1 4.3 3.9e-09 36.5 4.3 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KFP13560.1 - 2.4e-06 28.1 5.6 3.2 8.8 0.4 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13560.1 - 0.00022 21.4 0.0 2.4 8.5 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFP13560.1 - 0.0077 16.7 0.0 4.6 7.9 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain FAD-SLDH PF12318.8 KFP13560.1 - 0.59 10.2 3.7 0.76 9.8 2.0 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DER1 PF04511.15 KFP13561.1 - 3.8e-57 193.3 9.2 4.4e-57 193.1 9.2 1.0 1 0 0 1 1 1 1 Der1-like family DUF3341 PF11821.8 KFP13561.1 - 0.043 13.5 0.3 0.086 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Glyco_tranf_2_3 PF13641.6 KFP13567.1 - 4.1e-18 66.1 0.0 2.9e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 KFP13567.1 - 5.8e-18 64.8 5.4 1.5e-14 53.6 1.6 3.5 2 2 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 KFP13567.1 - 6.6e-09 35.8 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KFP13567.1 - 2.9e-06 27.3 18.7 3.4e-05 23.8 18.7 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KFP13567.1 - 0.0016 18.0 0.0 0.0038 16.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 RVT_1 PF00078.27 KFP13568.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH_17 PF18012.1 KFP13570.1 - 2e-28 97.9 0.2 7.6e-28 96.0 0.1 2.1 2 0 0 2 2 2 1 PH domain PH PF00169.29 KFP13570.1 - 1.1e-15 58.0 0.0 1.9e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 PH domain MTBP_mid PF14919.6 KFP13571.1 - 1.1e-149 498.3 0.6 1.9e-149 497.5 0.6 1.4 1 0 0 1 1 1 1 MDM2-binding MTBP_C PF14920.6 KFP13571.1 - 5.2e-125 416.3 8.8 9.3e-125 415.5 8.8 1.5 1 0 0 1 1 1 1 MDM2-binding MTBP_N PF14918.6 KFP13571.1 - 1.2e-96 323.1 1.1 2.1e-96 322.3 1.1 1.4 1 0 0 1 1 1 1 MDM2-binding AKAP2_C PF15304.6 KFP13571.1 - 0.002 17.5 3.9 0.0033 16.8 3.9 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus Ribosomal_L13 PF00572.18 KFP13574.1 - 1.1e-07 32.1 0.1 1.4e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 VWA PF00092.28 KFP13575.1 - 2e-111 370.1 0.1 1e-54 185.5 0.2 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain fn3 PF00041.21 KFP13575.1 - 6.6e-94 308.4 7.0 2.2e-13 50.3 0.0 8.3 8 0 0 8 8 8 8 Fibronectin type III domain Collagen PF01391.18 KFP13575.1 - 3.1e-37 126.1 166.5 2.4e-08 33.6 26.0 5.6 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFP13575.1 - 1.6e-31 109.1 0.0 6.1e-17 62.2 0.0 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF2369 PF10179.9 KFP13575.1 - 3.3e-07 30.6 0.2 31 5.0 0.0 6.7 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFP13575.1 - 7.1e-06 26.3 0.0 13 6.2 0.0 6.3 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFP13575.1 - 0.00059 20.1 0.1 0.33 11.3 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4959) DEP PF00610.21 KFP13576.1 - 8.5e-47 157.1 2.1 1.6e-25 88.9 0.4 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFP13576.1 - 2e-06 27.6 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP13576.1 - 0.0098 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Complex1_LYR_2 PF13233.6 KFP13576.1 - 0.012 16.3 1.7 0.041 14.6 1.7 2.0 1 1 0 1 1 1 0 Complex1_LYR-like PDZ PF00595.24 KFP13576.1 - 0.085 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain MCM6_C PF18263.1 KFP13576.1 - 0.32 11.2 2.0 2.1 8.6 0.1 2.6 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Dcc1 PF09724.9 KFP13577.1 - 1.7e-89 300.5 2.1 1.9e-89 300.3 2.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Peptidase_M1_N PF17900.1 KFP13578.1 - 5.6e-06 26.7 0.1 7.9e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KFP13578.1 - 0.0035 16.9 1.7 0.0086 15.7 1.7 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 KFP13578.1 - 0.018 15.4 0.1 0.84 10.1 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.22 KFP13578.1 - 0.46 10.9 3.2 9.6 6.8 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat Phosphodiest PF01663.22 KFP13580.1 - 7.6e-77 259.3 0.0 1.5e-41 143.2 0.3 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFP13580.1 - 1.5e-15 57.3 45.1 1.1e-08 35.3 13.8 3.1 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFP13580.1 - 2.2e-10 40.8 0.0 4.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFP13580.1 - 5.2e-05 22.8 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 Sulfatase MARVEL PF01284.23 KFP13581.1 - 1.1e-09 38.4 12.2 1.3e-09 38.2 12.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain 2-oxoacid_dh PF00198.23 KFP13581.1 - 0.0073 15.8 0.0 0.0092 15.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF1673 PF07895.11 KFP13581.1 - 0.025 14.3 3.4 0.032 13.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3687 PF12459.8 KFP13581.1 - 0.6 9.7 6.9 0.074 12.6 1.4 2.1 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein DUF4227 PF14004.6 KFP13581.1 - 4.6 7.3 7.4 0.31 11.0 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) Lectin_C PF00059.21 KFP13582.1 - 5.3e-18 65.7 0.0 7.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.18 KFP13582.1 - 2.9e-12 46.1 44.4 1.5e-07 31.0 17.9 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNFR_c6 PF00020.18 KFP13584.1 - 4.2e-28 97.5 38.3 3.7e-10 40.0 11.8 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Death PF00531.22 KFP13584.1 - 6.4e-18 64.7 2.2 1.7e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 Death domain TMCCDC2 PF15844.5 KFP13584.1 - 0.0097 15.9 0.3 0.025 14.5 0.3 1.7 1 0 0 1 1 1 1 Transmembrane and coiled-coil domain-containing protein 2 BCDHK_Adom3 PF10436.9 KFP13584.1 - 0.058 13.2 2.5 0.25 11.1 2.5 1.8 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SAM_2 PF07647.17 KFP13585.1 - 1.2e-17 63.8 0.9 1.6e-17 63.3 0.9 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP13585.1 - 1.5e-11 44.5 0.9 2.2e-11 44.0 0.9 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP13585.1 - 8.8e-09 35.2 0.1 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain RVT_1 PF00078.27 KFP13587.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med30 PF11315.8 KFP13594.1 - 1.5e-65 219.9 1.6 1.7e-65 219.7 1.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 MetOD2 PF18548.1 KFP13594.1 - 0.06 13.5 1.5 0.14 12.2 1.5 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 UPF0449 PF15136.6 KFP13594.1 - 0.091 13.2 3.9 0.21 12.0 3.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 NYD-SP28_assoc PF14775.6 KFP13594.1 - 0.27 11.4 4.7 0.56 10.3 4.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cation_efflux PF01545.21 KFP13595.1 - 1.9e-41 142.0 15.8 2.5e-41 141.6 15.8 1.2 1 0 0 1 1 1 1 Cation efflux family DUF1230 PF06799.11 KFP13595.1 - 0.91 9.6 2.7 1.6 8.9 0.4 2.4 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 Rad21_Rec8_N PF04825.13 KFP13598.1 - 1.6e-40 137.6 0.0 3.4e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFP13598.1 - 7.6e-23 79.6 0.2 3.6e-22 77.4 0.1 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KFP13598.1 - 0.0013 18.7 0.1 0.0013 18.7 0.1 1.8 2 0 0 2 2 2 1 Segregation and condensation protein ScpA Fcf1 PF04900.12 KFP13599.1 - 7.3e-24 84.0 0.7 1.6e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Fcf1 Di19_C PF14571.6 KFP13599.1 - 8.2 7.0 10.1 0.87 10.2 0.6 2.3 2 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal JAB PF01398.21 KFP13601.1 - 3.1e-20 72.3 0.3 3.1e-20 72.3 0.3 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-H2C2_5 PF13909.6 KFP13603.1 - 0.0049 16.6 2.3 0.0049 16.6 2.3 8.2 8 1 0 8 8 8 5 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFP13603.1 - 0.017 14.8 39.0 0.15 11.7 1.0 6.7 6 2 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2024 PF09630.10 KFP13603.1 - 0.19 11.6 0.0 0.19 11.6 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF2024) DUF5472 PF17566.2 KFP13603.1 - 0.64 10.0 3.6 27 4.8 0.1 4.2 4 1 1 5 5 5 0 Family of unknown function (DUF5472) Actin_micro PF17003.5 KFP13603.1 - 6.5 5.8 28.8 3.4 6.8 0.2 5.5 5 1 0 5 5 5 0 Putative actin-like family RVT_1 PF00078.27 KFP13607.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP13607.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase HAP1_N PF04849.13 KFP13608.1 - 2.1e-134 447.6 37.2 2.8e-134 447.1 37.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.8 KFP13608.1 - 6.5e-66 221.7 7.8 6.5e-66 221.7 7.8 2.8 3 0 0 3 3 3 1 Kinesin associated protein KASH_CCD PF14662.6 KFP13608.1 - 0.0054 16.6 39.2 0.0091 15.8 12.3 3.4 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KFP13608.1 - 0.23 11.5 16.5 0.23 11.5 1.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BSD PF03909.17 KFP13608.1 - 0.29 11.2 1.4 4.5 7.4 0.1 3.1 2 0 0 2 2 2 0 BSD domain Mod_r PF07200.13 KFP13608.1 - 0.62 10.2 32.4 0.67 10.0 10.1 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.11 KFP13608.1 - 2.2 8.5 35.6 4.5 7.4 22.9 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 KFP13608.1 - 2.2 8.3 38.3 0.24 11.4 7.1 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Shugoshin_N PF07558.11 KFP13608.1 - 2.8 7.9 9.3 3.2 7.7 0.3 3.8 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4226 PF10774.9 KFP13608.1 - 3.7 7.9 8.6 0.27 11.5 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) YabA PF06156.13 KFP13608.1 - 5.9 7.6 30.4 4.7 7.9 3.2 4.4 2 1 2 4 4 4 0 Initiation control protein YabA CorA PF01544.18 KFP13608.1 - 5.9 6.1 17.9 0.75 9.1 8.3 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 KFP13608.1 - 9.2 6.3 34.2 4.4 7.4 18.7 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Gastrin PF00918.17 KFP13609.1 - 1e-50 171.9 0.0 1.1e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Gastrin/cholecystokinin family SUI1 PF01253.22 KFP13610.1 - 2.8e-29 101.4 1.0 3.4e-29 101.2 1.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2729 PF10870.8 KFP13610.1 - 0.38 10.6 4.1 1.3 9.0 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2729) Rab_eff_C PF04698.12 KFP13611.1 - 0 1291.1 25.3 0 1290.9 25.3 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus FYVE_2 PF02318.16 KFP13612.1 - 2e-24 86.1 20.5 2.2e-24 86.0 20.5 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KFP13612.1 - 0.052 13.7 11.5 0.052 13.7 11.5 2.1 1 1 0 2 2 2 0 Piccolo Zn-finger Siva PF05458.12 KFP13612.1 - 0.87 9.3 15.6 0.97 9.1 15.6 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) C1_1 PF00130.22 KFP13612.1 - 4.9 7.1 22.7 1.9 8.5 16.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RVT_1 PF00078.27 KFP13613.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Carb_anhydrase PF00194.21 KFP13615.1 - 2.8e-66 223.7 0.1 3.1e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase VHS PF00790.19 KFP13617.1 - 1.7e-18 66.9 0.2 3.1e-18 66.0 0.2 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFP13617.1 - 1.2e-17 63.9 3.2 1.2e-17 63.9 3.2 1.8 2 0 0 2 2 2 1 GAT domain PilM_2 PF11104.8 KFP13617.1 - 0.052 12.6 0.2 0.08 11.9 0.2 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; CortBP2 PF09727.9 KFP13617.1 - 0.095 12.6 0.3 0.095 12.6 0.3 1.6 2 0 0 2 2 2 0 Cortactin-binding protein-2 CtaG_Cox11 PF04442.14 KFP13618.1 - 5e-58 195.4 0.2 5.6e-58 195.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 WW PF00397.26 KFP13619.1 - 1.9e-11 43.8 0.6 3.2e-11 43.1 0.6 1.4 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 KFP13619.1 - 4.7e-11 42.9 0.1 1.2e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP13619.1 - 4.5e-05 23.2 0.0 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain BORCS6 PF10157.9 KFP13619.1 - 0.036 14.3 3.4 0.29 11.3 0.0 2.5 1 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Pox_A11 PF05061.13 KFP13619.1 - 0.041 13.2 5.7 0.049 12.9 4.0 1.7 1 1 1 2 2 2 0 Poxvirus A11 Protein Rota_NSP4 PF01452.16 KFP13619.1 - 0.13 11.9 1.2 0.29 10.8 1.2 1.6 1 0 0 1 1 1 0 Rotavirus non structural protein LMBR1 PF04791.16 KFP13619.1 - 0.25 10.2 4.9 0.39 9.6 4.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KFP13619.1 - 0.41 9.9 14.0 0.92 8.8 13.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIVA PF05103.13 KFP13619.1 - 0.66 10.1 17.7 2 8.5 16.6 2.4 2 1 0 2 2 2 0 DivIVA protein Golgin_A5 PF09787.9 KFP13619.1 - 0.81 9.1 22.1 0.062 12.8 16.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KFP13619.1 - 1.1 9.3 13.8 0.41 10.7 5.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFP13619.1 - 1.5 8.9 26.8 0.059 13.4 18.2 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2721 PF11026.8 KFP13619.1 - 3.9 7.4 4.8 14 5.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) zf-C4H2 PF10146.9 KFP13619.1 - 8.4 6.6 12.9 2.5 8.4 9.7 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein bZIP_2 PF07716.15 KFP13620.1 - 1.1e-17 63.8 12.7 2.1e-17 62.9 12.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP13620.1 - 7.5e-05 22.8 9.1 0.00015 21.8 9.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFP13620.1 - 0.012 15.7 0.6 0.026 14.7 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 KFP13620.1 - 0.026 15.0 7.9 0.031 14.8 7.1 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor IER PF05760.12 KFP13620.1 - 0.1 12.9 0.7 0.15 12.3 0.3 1.5 1 1 1 2 2 2 0 Immediate early response protein (IER) HlyIII PF03006.20 KFP13621.1 - 1.7e-19 70.4 22.8 2.1e-19 70.1 22.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM100 PF16311.5 KFP13623.1 - 7.2e-67 223.0 0.4 8e-67 222.9 0.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 100 Neurensin PF14927.6 KFP13623.1 - 1.8e-05 24.4 1.2 0.018 14.7 0.3 2.1 1 1 1 2 2 2 2 Neurensin PIRT PF15099.6 KFP13623.1 - 0.00012 21.7 0.1 0.00014 21.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.6 KFP13623.1 - 0.00068 19.4 0.5 0.0007 19.4 0.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2371 PF10177.9 KFP13623.1 - 0.052 13.7 0.6 0.11 12.7 0.6 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Saf_2TM PF18303.1 KFP13623.1 - 0.057 13.0 0.4 0.1 12.2 0.4 1.5 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain UPF0542 PF15086.6 KFP13623.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TMEM252 PF15664.5 KFP13623.1 - 0.36 10.5 1.7 12 5.6 0.4 2.2 1 1 1 2 2 2 0 Transmembrane protein 252 family START PF01852.19 KFP13624.1 - 9.4e-34 116.7 0.0 1.1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 KFP13624.1 - 0.14 12.1 0.1 0.52 10.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) fn3 PF00041.21 KFP13625.1 - 5.8e-13 49.0 0.1 1.3e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.6 KFP13625.1 - 3.4e-07 30.7 0.1 1.5e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP13625.1 - 6.3e-07 29.6 0.1 0.0022 18.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP13625.1 - 9.8e-05 22.9 0.4 0.00059 20.4 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Pur_ac_phosph_N PF16656.5 KFP13625.1 - 0.0034 17.9 0.4 0.011 16.3 0.4 1.9 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Peptidase_M13_N PF05649.13 KFP13625.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M13 AHH PF14412.6 KFP13625.1 - 0.14 12.2 1.3 12 6.0 0.4 2.6 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH SulA PF03846.14 KFP13626.1 - 0.026 14.5 0.9 0.15 12.0 0.2 2.4 2 0 0 2 2 2 0 Cell division inhibitor SulA Hydin_ADK PF17213.3 KFP13626.1 - 0.66 10.2 7.1 0.085 13.1 0.5 2.3 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Noggin PF05806.12 KFP13627.1 - 1e-105 352.4 1.0 1.2e-105 352.2 1.0 1.0 1 0 0 1 1 1 1 Noggin DUF4543 PF15076.6 KFP13628.1 - 7.5e-46 154.2 1.8 9.1e-46 153.9 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) DAGK_acc PF00609.19 KFP13629.1 - 8.3e-51 172.5 0.0 1.4e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP13629.1 - 4.9e-17 61.7 0.2 1.2e-16 60.5 0.2 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KFP13629.1 - 8.8e-08 31.9 39.5 0.00045 20.0 10.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PRY PF13765.6 KFP13630.1 - 1.6e-16 59.7 0.0 4.6e-15 55.0 0.1 2.6 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFP13630.1 - 3.5e-13 49.7 0.3 8.4e-13 48.5 0.3 1.6 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KFP13630.1 - 0.00049 20.2 11.5 0.00049 20.2 11.5 2.7 3 0 0 3 3 3 1 B-box zinc finger AHH PF14412.6 KFP13630.1 - 0.063 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Peptidase_S10 PF00450.22 KFP13632.1 - 2e-85 287.7 0.3 2.3e-85 287.5 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KFP13632.1 - 0.018 14.3 0.2 0.41 9.9 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 UPF0114 PF03350.16 KFP13632.1 - 0.069 13.4 0.0 0.27 11.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein family, UPF0114 RBD-FIP PF09457.10 KFP13633.1 - 1.6e-17 63.1 3.3 1.6e-17 63.1 3.3 3.7 4 0 0 4 4 4 1 FIP domain bZIP_1 PF00170.21 KFP13633.1 - 7.6e-05 22.7 5.1 7.6e-05 22.7 5.1 5.8 3 2 2 5 5 5 2 bZIP transcription factor ZapB PF06005.12 KFP13633.1 - 0.0016 18.8 7.3 0.0016 18.8 7.3 4.9 3 2 1 4 4 4 2 Cell division protein ZapB bZIP_2 PF07716.15 KFP13633.1 - 0.008 16.2 3.9 0.008 16.2 3.9 6.0 5 1 0 5 5 5 1 Basic region leucine zipper DUF682 PF05081.12 KFP13633.1 - 0.04 13.7 1.1 0.1 12.3 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF682) DivIC PF04977.15 KFP13633.1 - 0.072 12.9 29.0 0.031 14.0 2.7 4.9 3 2 2 5 5 5 0 Septum formation initiator Leu_zip PF15294.6 KFP13633.1 - 0.09 12.3 39.3 0.36 10.3 23.6 3.1 2 1 1 3 3 3 0 Leucine zipper HAP1_N PF04849.13 KFP13633.1 - 0.12 11.6 47.6 0.04 13.1 32.6 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region HALZ PF02183.18 KFP13633.1 - 0.14 12.4 20.3 1.6 9.0 1.6 4.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 KFP13633.1 - 0.16 11.9 38.6 1.5 8.7 7.7 3.8 2 2 1 3 3 3 0 Axonemal dynein light chain FlaC_arch PF05377.11 KFP13633.1 - 0.4 11.1 25.0 0.32 11.4 0.9 4.9 5 1 1 6 6 5 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 KFP13633.1 - 0.49 10.3 17.9 0.31 10.9 1.3 4.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region VGPC1_C PF16799.5 KFP13633.1 - 0.52 10.3 15.3 0.32 11.0 1.6 4.3 3 1 1 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 MbeD_MobD PF04899.12 KFP13633.1 - 4.7 7.4 14.2 1.1 9.4 2.7 4.3 3 1 1 5 5 5 0 MbeD/MobD like PikAIV_N PF18605.1 KFP13633.1 - 8.9 6.0 13.5 0.4 10.3 0.8 4.1 4 0 0 4 4 4 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain U3_assoc_6 PF08640.11 KFP13634.1 - 8.4e-15 54.6 5.4 8.4e-15 54.6 5.4 3.6 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KFP13634.1 - 1e-05 25.9 3.0 1.1 10.2 0.2 5.9 4 2 2 6 6 6 2 Tetratricopeptide repeat FadR_C PF07840.12 KFP13634.1 - 0.014 15.3 0.3 0.049 13.5 0.1 2.0 1 1 0 1 1 1 0 FadR C-terminal domain HMGL-like PF00682.19 KFP13634.1 - 0.039 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 HMGL-like vWF_A PF12450.8 KFP13634.1 - 0.072 13.1 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 von Willebrand factor TPR_16 PF13432.6 KFP13634.1 - 0.094 13.4 0.2 8.1 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TnpV PF14198.6 KFP13634.1 - 0.3 11.1 3.5 0.19 11.7 0.6 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV VEFS-Box PF09733.9 KFP13635.1 - 1.5e-54 183.5 2.9 3.2e-54 182.5 2.9 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF2070 PF09843.9 KFP13635.1 - 0.004 15.5 0.0 0.0059 15.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) zf-C2H2 PF00096.26 KFP13635.1 - 7.4 7.2 6.5 28 5.4 6.5 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type fn3 PF00041.21 KFP13636.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain GABP-alpha PF11620.8 KFP13636.1 - 0.29 11.4 1.1 0.57 10.4 0.4 1.9 2 0 0 2 2 2 0 GA-binding protein alpha chain AAA PF00004.29 KFP13637.1 - 2.2e-08 34.6 1.0 2.6e-06 27.9 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP13637.1 - 0.00041 20.8 0.0 0.0017 18.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KFP13637.1 - 0.0027 17.6 12.5 0.075 12.9 0.0 4.1 4 0 0 4 4 4 2 Rad17 P-loop domain AAA_22 PF13401.6 KFP13637.1 - 0.0059 16.9 0.0 0.031 14.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFP13637.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.12 KFP13637.1 - 0.014 15.1 0.0 0.046 13.5 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFP13637.1 - 0.081 12.9 0.0 0.27 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFP13637.1 - 0.096 13.2 0.0 0.096 13.2 0.0 4.0 5 0 0 5 5 5 0 AAA domain ArfGap PF01412.18 KFP13638.1 - 1.1e-25 89.9 0.1 2.1e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP13638.1 - 1.2e-19 70.8 0.3 3.6e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 KFP13638.1 - 2.8e-07 30.7 3.8 0.0044 17.3 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP13638.1 - 7.1e-07 29.6 5.3 0.014 15.8 0.2 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain EF_assoc_2 PF08356.12 KFP13639.1 - 2e-36 123.8 0.0 5.9e-36 122.3 0.0 1.8 2 0 0 2 2 1 1 EF hand associated EF_assoc_1 PF08355.12 KFP13639.1 - 1.5e-29 101.4 0.9 9.9e-29 98.8 0.6 2.2 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 KFP13639.1 - 4.6e-24 84.8 0.1 3.8e-16 59.1 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KFP13639.1 - 3.9e-08 33.5 0.0 6.3e-05 23.2 0.0 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KFP13639.1 - 9.4e-07 27.9 3.2 0.015 14.8 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP13639.1 - 1.9e-06 28.2 0.8 0.011 16.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP13639.1 - 2.9e-06 26.7 2.6 0.003 17.4 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain RsgA_GTPase PF03193.16 KFP13639.1 - 3.9e-05 23.6 2.0 0.26 11.2 0.1 4.0 5 0 0 5 5 5 2 RsgA GTPase EF-hand_8 PF13833.6 KFP13639.1 - 0.00089 19.1 0.6 0.68 9.8 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair Rad4 PF03835.15 KFP13639.1 - 0.0044 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Dynamin_N PF00350.23 KFP13639.1 - 0.025 14.7 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 KFP13639.1 - 0.028 14.5 0.2 4.6 7.4 0.0 3.0 2 2 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KFP13639.1 - 0.091 12.8 0.0 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFP13639.1 - 0.11 13.0 0.0 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter EF-hand_5 PF13202.6 KFP13639.1 - 0.15 11.6 3.2 6.6 6.4 0.1 2.7 2 0 0 2 2 2 0 EF hand PduV-EutP PF10662.9 KFP13639.1 - 0.19 11.5 0.3 1.9 8.2 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF-hand_4 PF12763.7 KFP13639.1 - 0.55 10.2 1.8 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Rhomboid PF01694.22 KFP13640.1 - 5.9e-34 117.2 11.7 5.9e-34 117.2 11.7 1.9 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.6 KFP13640.1 - 3.2e-09 37.1 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP13640.1 - 7.1e-07 29.0 0.0 7.1e-05 22.6 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP13640.1 - 1.3e-06 27.5 0.0 0.0086 15.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 KFP13640.1 - 0.00032 21.5 0.0 0.00055 20.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain DUF5580 PF17743.1 KFP13640.1 - 0.00043 18.9 0.0 0.00054 18.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_6 PF13405.6 KFP13640.1 - 0.00088 19.0 0.1 0.056 13.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF3087 PF11286.8 KFP13640.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF4203 PF13886.6 KFP13640.1 - 2.3 7.8 17.0 2.7 7.6 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) ARL6IP6 PF15062.6 KFP13640.1 - 4 7.6 5.4 1.6 8.9 0.2 2.5 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix Njmu-R1 PF15053.6 KFP13641.1 - 5.9e-180 597.9 0.1 6.6e-180 597.7 0.1 1.0 1 0 0 1 1 1 1 Mjmu-R1-like protein family zf-FCS PF06467.14 KFP13642.1 - 0.59 10.1 10.5 0.4 10.6 1.3 2.8 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 KFP13642.1 - 0.63 11.0 8.1 3.4 8.7 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP13642.1 - 2.6 8.7 7.5 16 6.2 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type AlbA_2 PF04326.14 KFP13643.1 - 0.00083 19.7 0.7 0.0062 16.9 0.4 2.5 2 0 0 2 2 2 1 Putative DNA-binding domain RNA_pol_Rpb2_2 PF04561.14 KFP13643.1 - 0.015 15.0 0.3 0.051 13.2 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 ANAPC3 PF12895.7 KFP13643.1 - 0.095 12.9 0.4 0.28 11.5 0.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFP13643.1 - 2.1 8.9 5.3 0.91 10.1 1.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MMM1 PF10296.9 KFP13644.1 - 0.00098 18.3 4.4 0.0014 17.7 0.0 3.0 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Ig_2 PF13895.6 KFP13645.1 - 3.6e-44 149.0 3.6 7.3e-09 35.8 0.0 6.2 5 1 1 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.6 KFP13645.1 - 8.5e-39 132.0 0.3 2.5e-05 24.8 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFP13645.1 - 3.1e-27 94.6 7.2 0.00023 21.3 0.0 7.5 6 2 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP13645.1 - 5.9e-15 55.1 15.5 0.0081 16.2 0.2 8.0 5 3 1 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.17 KFP13645.1 - 8.8e-14 51.6 10.1 0.45 10.7 0.0 7.9 6 3 3 9 9 9 5 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 KFP13645.1 - 3.4e-11 43.0 0.0 0.011 15.7 0.0 5.1 4 1 1 5 5 5 2 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP13645.1 - 9.4e-09 35.2 5.5 0.11 12.6 0.1 5.8 5 1 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP13645.1 - 1.5e-08 34.1 0.0 0.25 11.0 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 KFP13645.1 - 1.2e-05 25.7 1.6 0.047 14.1 0.0 5.3 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_Tie2_1 PF10430.9 KFP13645.1 - 0.15 12.5 0.4 1.2 9.6 0.0 2.7 3 0 0 3 3 2 0 Tie-2 Ig-like domain 1 ICAM_N PF03921.14 KFP13645.1 - 0.88 9.3 3.1 1.9 8.2 0.2 2.9 3 0 0 3 3 3 0 Intercellular adhesion molecule (ICAM), N-terminal domain Ig_C17orf99 PF17736.1 KFP13646.1 - 1.7e-24 85.7 1.8 1.4e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 C17orf99 Ig domain Ig_3 PF13927.6 KFP13646.1 - 5.2e-23 81.4 0.7 5.5e-11 42.9 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP13646.1 - 2.8e-19 69.2 2.5 1.2e-09 38.3 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP13646.1 - 1.7e-13 50.5 2.4 2.1e-07 31.0 0.3 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP13646.1 - 9.5e-11 41.6 0.0 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP13646.1 - 3.4e-06 27.2 5.9 1.8 8.8 0.1 4.1 2 2 2 4 4 4 4 Immunoglobulin V-set domain Ig_C19orf38 PF17737.1 KFP13646.1 - 2.9e-05 24.3 0.1 0.0023 18.2 0.0 2.4 2 0 0 2 2 2 1 Ig domain in C19orf38 (HIDE1) C2-set_2 PF08205.12 KFP13646.1 - 4e-05 23.6 0.1 0.056 13.5 0.0 2.2 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain MBG_2 PF18676.1 KFP13646.1 - 0.014 16.0 0.6 2 9.1 0.1 2.4 2 0 0 2 2 2 0 MBG domain (YGX type) CHB_HEX_C_1 PF13290.6 KFP13646.1 - 0.11 12.6 0.0 6.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain MG2 PF01835.19 KFP13646.1 - 0.15 12.5 0.0 3.5 8.1 0.0 2.3 2 0 0 2 2 2 0 MG2 domain HGTP_anticodon PF03129.20 KFP13647.1 - 1.7e-11 44.1 0.0 2.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain DEAD PF00270.29 KFP13648.1 - 1e-48 165.4 0.0 7.4e-48 162.6 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP13648.1 - 2.6e-31 108.3 0.0 1e-30 106.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain P68HR PF08061.11 KFP13648.1 - 4.9e-28 97.0 21.0 3.2e-14 52.8 4.6 2.6 2 0 0 2 2 2 2 P68HR (NUC004) repeat ResIII PF04851.15 KFP13648.1 - 9.9e-05 22.4 0.0 0.00097 19.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFP13648.1 - 0.0071 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HECT PF00632.25 KFP13649.1 - 1.9e-102 342.9 0.0 2.5e-102 342.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP13649.1 - 5.6e-30 103.1 9.4 2.4e-11 43.5 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KFP13649.1 - 1.5e-15 57.3 0.0 3.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain HPS3_N PF14761.6 KFP13649.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Arm PF00514.23 KFP13650.1 - 2.9e-81 265.3 4.4 1.6e-10 40.7 0.0 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP13650.1 - 2.9e-30 104.6 6.7 8.8e-30 103.0 6.7 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFP13650.1 - 1.5e-24 85.3 3.7 2.1e-24 84.8 2.1 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFP13650.1 - 1.8e-19 69.8 0.1 2.9e-06 27.7 0.0 5.6 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFP13650.1 - 3e-11 43.5 0.0 0.0088 16.4 0.0 5.4 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 KFP13650.1 - 4.4e-08 32.7 0.9 0.15 12.4 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat UxaC PF02614.14 KFP13650.1 - 0.052 12.4 0.0 5.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Glucuronate isomerase SYCP2_ARLD PF18581.1 KFP13650.1 - 0.06 13.4 0.2 32 4.5 0.0 3.7 3 1 0 4 4 4 0 Synaptonemal complex 2 armadillo-repeat-like domain ECF-ribofla_trS PF07155.12 KFP13650.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component NTR PF01759.21 KFP13652.1 - 0.042 13.7 0.1 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 UNC-6/NTR/C345C module KRAB PF01352.27 KFP13653.1 - 4.7e-19 67.8 0.0 5.8e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 KRAB box zf-tcix PF14952.6 KFP13654.1 - 1e-20 73.0 8.3 2.3e-20 71.9 8.3 1.6 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 KFP13654.1 - 0.0038 16.6 1.7 0.011 15.2 1.7 1.8 1 0 0 1 1 1 1 Mu-like prophage protein Com RRM_1 PF00076.22 KFP13655.1 - 1.6e-66 220.1 0.0 2e-23 82.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP13655.1 - 3.2e-11 42.9 0.0 1.1e-05 25.2 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP13655.1 - 1.7e-07 31.3 0.2 0.33 11.1 0.0 4.3 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP13655.1 - 0.00012 22.0 0.4 0.1 12.6 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP13655.1 - 0.00014 22.2 0.1 4.9 7.4 0.0 3.3 2 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Calcipressin PF04847.12 KFP13655.1 - 0.00019 21.2 0.0 0.067 12.9 0.0 2.6 3 0 0 3 3 3 1 Calcipressin RRM_3 PF08777.11 KFP13655.1 - 0.00046 20.2 0.0 0.97 9.5 0.0 3.1 2 1 1 3 3 3 1 RNA binding motif Nup35_RRM PF05172.13 KFP13655.1 - 0.0028 17.6 0.2 0.16 12.0 0.1 3.0 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KFP13655.1 - 0.0037 17.2 0.0 0.93 9.5 0.0 3.2 3 0 0 3 3 3 1 DbpA RNA binding domain XOO_2897-deam PF14440.6 KFP13655.1 - 0.081 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Cas_Cas2CT1978 PF09707.10 KFP13655.1 - 0.13 12.4 0.0 12 6.1 0.0 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) LSM PF01423.22 KFP13656.1 - 4e-20 71.3 0.2 4.2e-20 71.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain Amelogenin PF02948.15 KFP13657.1 - 6 7.5 22.5 4.3 8.0 10.6 2.2 1 1 1 2 2 2 0 Amelogenin NAPRTase PF04095.16 KFP13658.1 - 9.8e-73 244.7 0.0 1.3e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 KFP13658.1 - 3.5e-36 123.6 2.3 3.5e-36 123.6 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5598) PI3Ka PF00613.20 KFP13661.1 - 1.3e-63 213.7 2.0 1.3e-63 213.7 2.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP13661.1 - 5.5e-57 193.4 0.7 2.2e-56 191.4 0.7 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 KFP13661.1 - 1.9e-27 95.5 6.1 2.9e-26 91.7 0.0 3.6 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFP13661.1 - 8.6e-16 58.1 0.4 2.8e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP13661.1 - 0.0037 16.6 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) BMFP PF04380.13 KFP13661.1 - 0.13 12.8 0.3 0.88 10.1 0.1 2.4 2 0 0 2 2 2 0 Membrane fusogenic activity cNMP_binding PF00027.29 KFP13663.1 - 2.4e-37 126.9 0.1 6.3e-20 71.1 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain AXH PF08517.12 KFP13664.1 - 5.9e-35 120.3 0.0 1.1e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.19 KFP13664.1 - 6.5e-15 55.3 0.9 1.2e-14 54.4 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP13664.1 - 2.6e-09 37.5 1.6 5.2e-09 36.6 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFP13664.1 - 0.0028 17.0 0.2 0.0048 16.2 0.2 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Peptidase_S64 PF08192.11 KFP13664.1 - 0.054 12.0 1.7 0.085 11.3 1.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 COG5 PF10392.9 KFP13665.1 - 3.3e-31 108.2 2.2 3.3e-31 108.2 2.2 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KFP13665.1 - 9.4e-10 38.4 3.4 2.7e-09 37.0 0.3 3.4 2 1 1 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 KFP13665.1 - 0.0003 20.9 0.5 0.0003 20.9 0.5 3.9 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 COMMD1_N PF17221.3 KFP13665.1 - 0.044 14.1 0.1 0.23 11.7 0.1 2.3 1 0 0 1 1 1 0 COMMD1 N-terminal domain FapA PF03961.13 KFP13665.1 - 0.1 11.2 0.3 0.3 9.7 0.0 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 KFP13665.1 - 0.21 11.8 2.8 3.4 7.9 0.3 3.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DLP_helical PF18709.1 KFP13665.1 - 0.75 8.9 4.1 0.25 10.5 0.1 2.2 3 0 0 3 3 3 0 Dynamin-like helical domain Vps54_N PF10475.9 KFP13665.1 - 0.88 8.8 6.5 0.14 11.4 1.4 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Fzo_mitofusin PF04799.13 KFP13665.1 - 8 6.0 7.0 4.4 6.8 0.1 3.4 3 1 0 3 3 3 0 fzo-like conserved region 7tm_1 PF00001.21 KFP13666.1 - 2e-25 89.6 22.5 2.6e-25 89.3 22.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.11 KFP13666.1 - 1.7 7.6 17.3 0.019 14.0 8.5 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF1980 PF09323.10 KFP13666.1 - 3.2 7.6 12.4 2.3 8.1 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) Dus PF01207.17 KFP13667.1 - 1.7e-74 250.7 0.2 2e-74 250.5 0.2 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFP13667.1 - 3.1e-06 26.8 0.5 0.0023 17.5 0.0 1.5 1 1 1 2 2 2 2 Histidine biosynthesis protein TMP-TENI PF02581.17 KFP13667.1 - 0.0059 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 KFP13667.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family ThiG PF05690.14 KFP13667.1 - 0.069 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KFP13667.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Bap31 PF05529.12 KFP13668.1 - 2.7e-45 153.5 5.9 2.7e-45 153.5 5.9 1.7 1 1 1 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFP13668.1 - 8.4e-12 44.9 3.3 8.4e-12 44.9 3.3 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain MPS2 PF17060.5 KFP13668.1 - 0.00021 20.7 4.5 0.00034 20.0 4.5 1.3 1 0 0 1 1 1 1 Monopolar spindle protein 2 ADIP PF11559.8 KFP13668.1 - 0.00099 19.2 9.9 0.0017 18.5 9.9 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HALZ PF02183.18 KFP13668.1 - 0.0025 18.0 8.4 0.12 12.6 0.1 3.0 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF1664 PF07889.12 KFP13668.1 - 0.0038 17.3 2.3 0.0058 16.7 1.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Dynamitin PF04912.14 KFP13668.1 - 0.0083 15.5 6.4 0.011 15.1 6.4 1.1 1 0 0 1 1 1 1 Dynamitin AATF-Che1 PF13339.6 KFP13668.1 - 0.02 15.6 3.7 0.033 14.9 3.7 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Sec34 PF04136.15 KFP13668.1 - 0.021 14.7 7.0 0.059 13.3 1.3 2.9 3 0 0 3 3 3 0 Sec34-like family Syntaxin PF00804.25 KFP13668.1 - 0.023 14.4 7.6 0.032 13.9 7.6 1.2 1 0 0 1 1 1 0 Syntaxin HOOK PF05622.12 KFP13668.1 - 0.029 12.6 11.6 0.033 12.3 11.6 1.0 1 0 0 1 1 1 0 HOOK protein APC_N_CC PF16689.5 KFP13668.1 - 0.034 14.2 4.2 0.055 13.5 2.9 2.0 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain YabA PF06156.13 KFP13668.1 - 0.036 14.7 8.5 1 10.0 3.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA End3 PF12761.7 KFP13668.1 - 0.058 13.6 7.0 0.08 13.1 7.0 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3450 PF11932.8 KFP13668.1 - 0.059 12.7 6.2 0.087 12.1 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mod_r PF07200.13 KFP13668.1 - 0.08 13.0 8.7 0.28 11.3 8.7 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 KFP13668.1 - 0.099 13.1 11.9 0.59 10.6 11.6 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PspA_IM30 PF04012.12 KFP13668.1 - 0.1 12.2 11.3 0.17 11.5 11.3 1.3 1 0 0 1 1 1 0 PspA/IM30 family Cluap1 PF10234.9 KFP13668.1 - 0.11 11.9 10.8 0.15 11.5 10.8 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 APG6_N PF17675.1 KFP13668.1 - 0.12 12.9 11.1 0.21 12.1 11.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region JAKMIP_CC3 PF16034.5 KFP13668.1 - 0.14 12.1 7.6 0.23 11.4 7.6 1.5 1 0 0 1 1 1 0 JAKMIP CC3 domain YkyA PF10368.9 KFP13668.1 - 0.14 11.8 10.1 0.21 11.2 10.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein FlaC_arch PF05377.11 KFP13668.1 - 0.16 12.4 3.3 0.29 11.6 0.1 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.13 KFP13668.1 - 0.16 12.4 5.2 0.14 12.6 3.1 2.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ZnuA PF01297.17 KFP13668.1 - 0.18 11.1 1.5 0.27 10.6 1.5 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Sec2p PF06428.11 KFP13668.1 - 0.22 11.5 9.8 0.091 12.7 4.5 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Fez1 PF06818.15 KFP13668.1 - 0.24 11.8 11.0 0.34 11.4 11.0 1.2 1 0 0 1 1 1 0 Fez1 Selenoprotein_S PF06936.11 KFP13668.1 - 0.32 10.8 5.8 0.31 10.8 4.7 1.5 1 1 1 2 2 2 0 Selenoprotein S (SelS) Exonuc_VII_L PF02601.15 KFP13668.1 - 0.32 10.5 4.1 0.36 10.4 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LPP PF04728.13 KFP13668.1 - 0.62 10.5 4.0 1.3 9.4 0.5 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Cnn_1N PF07989.11 KFP13668.1 - 0.84 9.8 8.8 1.1 9.5 7.5 2.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 WXG100 PF06013.12 KFP13668.1 - 0.87 9.9 4.1 1.4 9.2 0.2 2.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF2508 PF10704.9 KFP13668.1 - 1.1 9.4 6.2 0.62 10.3 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) Nup54_57_C PF18570.1 KFP13668.1 - 1.5 8.5 6.2 2.5 7.8 1.3 2.8 2 1 1 3 3 3 0 NUP57/Nup54 C-terminal domain UPF0449 PF15136.6 KFP13668.1 - 1.7 9.1 8.9 23 5.5 7.5 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TMF_DNA_bd PF12329.8 KFP13668.1 - 2.9 8.0 14.3 2.7 8.0 3.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.6 KFP13668.1 - 4.7 7.4 14.8 1.6 8.9 6.4 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0242 PF06785.11 KFP13668.1 - 7.7 6.6 14.8 1.9 8.5 9.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sulfate_transp PF00916.20 KFP13669.1 - 1.3e-106 356.6 22.7 1.7e-106 356.2 22.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP13669.1 - 1e-33 115.4 0.5 2.2e-33 114.4 0.5 1.6 1 0 0 1 1 1 1 STAS domain zf_Hakai PF18408.1 KFP13670.1 - 2.5e-21 75.0 2.3 5e-21 74.1 2.3 1.5 1 0 0 1 1 1 1 C2H2 Hakai zinc finger domain zf-C3HC4_3 PF13920.6 KFP13670.1 - 2.5e-05 24.0 7.9 5.2e-05 23.0 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP13670.1 - 0.0012 18.7 7.5 0.0027 17.6 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP13670.1 - 0.0012 18.6 8.7 0.0027 17.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP13670.1 - 0.0016 18.3 9.6 0.0066 16.3 9.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP13670.1 - 0.02 14.8 6.5 0.043 13.7 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 KFP13670.1 - 0.043 13.8 7.2 0.21 11.6 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KFP13670.1 - 0.053 13.5 10.4 0.1 12.6 10.4 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_2 PF13639.6 KFP13670.1 - 0.069 13.5 8.5 0.17 12.3 8.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KFP13670.1 - 0.11 12.5 6.8 0.37 10.8 6.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFP13670.1 - 0.77 9.6 8.1 0.1 12.4 3.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 KFP13670.1 - 0.79 9.5 5.6 1.9 8.3 5.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger C1_4 PF07975.12 KFP13670.1 - 5.9 7.2 10.1 7.3 6.9 8.5 2.0 2 1 0 2 2 2 0 TFIIH C1-like domain Pyr_redox_2 PF07992.14 KFP13671.1 - 3.2e-66 223.5 7.7 3.2e-66 223.5 7.7 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP13671.1 - 1.2e-40 138.2 0.2 1.2e-40 138.2 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP13671.1 - 1e-17 64.5 8.4 9.4e-17 61.4 1.3 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP13671.1 - 2.4e-10 40.2 3.4 2.3e-07 30.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFP13671.1 - 4.3e-09 36.2 0.1 4.3e-09 36.2 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFP13671.1 - 5.3e-09 35.6 3.0 9.5e-07 28.2 0.3 3.0 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KFP13671.1 - 2.1e-06 27.1 10.0 4.7e-06 25.9 4.2 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFP13671.1 - 8.6e-06 25.9 7.3 6.5e-05 23.1 0.1 2.7 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFP13671.1 - 7.4e-05 22.0 2.0 0.1 11.8 0.3 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KFP13671.1 - 0.00011 21.6 5.2 0.0068 15.7 0.2 3.5 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.14 KFP13671.1 - 0.00018 20.4 11.4 0.0017 17.2 0.5 3.7 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KFP13671.1 - 0.00019 20.8 8.9 0.034 13.5 0.9 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFP13671.1 - 0.00057 19.2 0.9 0.0013 18.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 KFP13671.1 - 0.0044 16.6 7.9 1.3 8.6 0.2 3.6 4 0 0 4 4 4 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KFP13671.1 - 0.029 13.9 9.9 3.2 7.2 0.1 4.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase UPF0227 PF05728.12 KFP13671.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) 3HCDH_N PF02737.18 KFP13671.1 - 0.13 12.1 5.5 1.3 8.9 1.2 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFP13671.1 - 6.6 6.1 7.0 2.8 7.3 0.2 3.1 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COPIIcoated_ERV PF07970.12 KFP13672.1 - 7.1e-50 169.9 0.3 1e-49 169.4 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFP13672.1 - 1e-24 86.7 0.3 2.3e-24 85.6 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 KFP13673.1 - 5e-41 140.8 0.0 1.4e-40 139.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP13673.1 - 4.2e-40 137.7 0.0 2.3e-39 135.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Roc PF08477.13 KFP13673.1 - 9.7e-31 106.5 0.1 2.9e-30 105.0 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 KFP13673.1 - 1.6e-27 95.0 35.4 3.2e-07 30.0 2.4 6.8 5 1 0 6 6 6 5 Leucine rich repeat COR PF16095.5 KFP13673.1 - 2.5e-26 92.7 0.6 6.1e-25 88.2 0.3 2.5 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 KFP13673.1 - 1.9e-20 72.6 48.1 5.6e-07 29.8 0.2 8.8 4 2 3 9 9 8 6 Leucine Rich repeats (2 copies) Ras PF00071.22 KFP13673.1 - 1.9e-15 56.9 0.0 5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP13673.1 - 2e-07 30.6 0.8 4.8e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_2 PF12796.7 KFP13673.1 - 1.2e-05 25.7 0.6 0.00012 22.6 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) LRR_9 PF14580.6 KFP13673.1 - 0.0001 21.9 11.7 0.02 14.4 1.2 3.6 1 1 3 4 4 4 2 Leucine-rich repeat Gtr1_RagA PF04670.12 KFP13673.1 - 0.00017 21.0 0.1 0.00038 19.9 0.1 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arm PF00514.23 KFP13673.1 - 0.0055 16.7 0.2 0.11 12.6 0.1 3.3 3 0 0 3 3 2 1 Armadillo/beta-catenin-like repeat T2SSE PF00437.20 KFP13673.1 - 0.006 15.7 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.22 KFP13673.1 - 0.014 14.6 0.2 0.038 13.2 0.2 1.8 1 1 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 KFP13673.1 - 0.014 14.6 0.2 0.059 12.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP13673.1 - 0.014 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 KFP13673.1 - 0.018 14.6 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KFP13673.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_4 PF13637.6 KFP13673.1 - 0.027 15.1 0.2 0.49 11.0 0.0 3.3 3 1 1 4 4 3 0 Ankyrin repeats (many copies) ABC_tran PF00005.27 KFP13673.1 - 0.028 14.9 0.1 0.086 13.4 0.1 1.8 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KFP13673.1 - 0.03 14.1 0.3 0.072 12.8 0.3 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFP13673.1 - 0.03 14.2 1.1 0.066 13.1 0.2 2.1 2 0 0 2 2 1 0 NACHT domain AAA_22 PF13401.6 KFP13673.1 - 0.035 14.4 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KFP13673.1 - 0.037 12.9 0.1 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 KFP13673.1 - 0.04 13.3 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.14 KFP13673.1 - 0.045 13.6 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Kdo PF06293.14 KFP13673.1 - 0.056 12.8 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_16 PF13191.6 KFP13673.1 - 0.072 13.5 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFP13673.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KFP13673.1 - 0.085 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_33 PF13671.6 KFP13673.1 - 0.088 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFP13673.1 - 0.74 10.3 6.2 0.53 10.8 0.0 3.3 4 0 0 4 4 3 0 AAA domain LRR_6 PF13516.6 KFP13673.1 - 1.2 9.4 40.1 4.2 7.7 0.1 10.3 11 0 0 11 11 10 0 Leucine Rich repeat Sugar_tr PF00083.24 KFP13674.1 - 1.2e-93 314.4 13.0 9.5e-69 232.4 2.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFP13674.1 - 3.7e-15 55.7 23.5 1.6e-11 43.7 13.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Ral PF11058.8 KFP13674.1 - 0.11 12.1 1.2 0.21 11.2 1.2 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral PSI_integrin PF17205.3 KFP13674.1 - 1.5 8.6 5.7 2.9 7.7 5.7 1.5 1 0 0 1 1 1 0 Integrin plexin domain ABC_membrane_2 PF06472.15 KFP13676.1 - 3.4e-99 331.6 4.0 4.5e-99 331.2 4.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFP13676.1 - 9.3e-19 68.3 0.0 1.8e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFP13676.1 - 9e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFP13676.1 - 0.00075 20.1 0.2 0.0042 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP13676.1 - 0.0041 16.8 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cyto_heme_lyase PF01265.17 KFP13676.1 - 0.0056 16.3 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Rad17 PF03215.15 KFP13676.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 KFP13676.1 - 0.016 14.6 0.1 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 KFP13676.1 - 0.021 13.6 0.1 0.038 12.8 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein SseC PF04888.12 KFP13676.1 - 0.03 13.9 0.0 0.076 12.6 0.0 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ARID PF01388.21 KFP13676.1 - 0.056 14.1 0.1 0.18 12.5 0.1 1.9 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain AAA_16 PF13191.6 KFP13676.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Kinesin PF00225.23 KFP13677.1 - 3e-107 358.4 0.3 3e-107 358.4 0.3 3.3 2 1 1 4 4 4 1 Kinesin motor domain WD40 PF00400.32 KFP13677.1 - 6.5e-30 102.8 6.6 3.6e-05 24.4 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Microtub_bd PF16796.5 KFP13677.1 - 4.1e-23 82.0 0.0 4.1e-23 82.0 0.0 3.0 2 1 0 2 2 2 1 Microtubule binding Csm1_N PF18504.1 KFP13677.1 - 0.018 15.4 1.0 0.018 15.4 1.0 10.1 7 3 4 12 12 12 0 Csm1 N-terminal domain DUF3800 PF12686.7 KFP13677.1 - 2.9 8.6 10.8 11 6.7 0.1 4.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3800) Glyco_hydro_31 PF01055.26 KFP13678.1 - 3.8e-64 217.5 0.4 4.2e-64 217.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Aminotran_MocR PF12897.7 KFP13678.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DIE2_ALG10 PF04922.12 KFP13680.1 - 1.6e-135 452.4 28.2 2e-135 452.1 28.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family CGI-121 PF08617.10 KFP13681.1 - 1e-44 152.5 1.0 1.1e-44 152.4 1.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 TrmB PF01978.19 KFP13681.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Exonuc_VII_S PF02609.16 KFP13681.1 - 0.11 12.5 0.2 0.31 11.1 0.2 1.7 1 0 0 1 1 1 0 Exonuclease VII small subunit GTSE1_N PF15259.6 KFP13683.1 - 4.1e-58 195.7 2.4 4.1e-58 195.7 2.4 2.2 2 0 0 2 2 2 1 G-2 and S-phase expressed 1 tRNA_Me_trans PF03054.16 KFP13684.1 - 3e-125 417.7 0.0 3.5e-125 417.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase Cadherin PF00028.17 KFP13685.1 - 9.3e-156 506.8 11.1 5.7e-23 81.2 0.8 8.8 8 0 0 8 8 8 8 Cadherin domain GAIN PF16489.5 KFP13685.1 - 1.7e-68 230.2 0.2 2.7e-68 229.5 0.2 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Laminin_G_2 PF02210.24 KFP13685.1 - 9.8e-46 155.4 0.2 5e-26 91.7 0.0 3.1 2 0 0 2 2 2 2 Laminin G domain 7tm_2 PF00002.24 KFP13685.1 - 1.4e-38 132.6 16.6 2.3e-38 131.9 16.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_1 PF00054.23 KFP13685.1 - 8.2e-24 84.3 0.6 1.1e-15 58.0 0.0 3.7 2 1 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP13685.1 - 3.8e-19 68.6 111.8 4.8e-07 30.0 8.2 9.0 9 0 0 9 9 7 6 EGF-like domain GPS PF01825.21 KFP13685.1 - 7.5e-15 55.2 3.4 7.5e-15 55.2 3.4 3.2 3 1 0 3 3 1 1 GPCR proteolysis site, GPS, motif Laminin_EGF PF00053.24 KFP13685.1 - 3.9e-08 33.3 13.8 3.9e-08 33.3 13.8 8.8 6 2 3 9 9 7 2 Laminin EGF domain Cadherin_4 PF17803.1 KFP13685.1 - 1.8e-07 31.7 42.2 0.13 12.9 0.0 9.3 9 0 0 9 9 9 4 Bacterial cadherin-like domain hEGF PF12661.7 KFP13685.1 - 4e-07 30.4 85.2 0.00021 21.8 6.5 8.7 8 0 0 8 8 7 4 Human growth factor-like EGF Cadherin_2 PF08266.12 KFP13685.1 - 0.00035 20.3 0.0 35 4.3 0.0 6.0 6 0 0 6 6 6 0 Cadherin-like Histone PF00125.24 KFP13687.1 - 5.6e-26 91.4 0.4 7.2e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP13687.1 - 9.1e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP13687.1 - 0.0034 17.8 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFP13687.1 - 0.0047 17.0 0.3 0.0055 16.7 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein GRAM PF02893.20 KFP13689.1 - 1.7e-22 79.4 0.0 3.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 KFP13689.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Tmemb_cc2 PF10267.9 KFP13689.1 - 0.023 13.8 3.1 0.04 13.1 3.1 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF639 PF04842.12 KFP13689.1 - 0.13 11.6 1.5 0.15 11.4 0.2 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Arrestin_N PF00339.29 KFP13693.1 - 2.6e-33 115.1 0.4 2.2e-31 108.9 0.3 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFP13693.1 - 1.3e-24 87.2 0.0 5.1e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 KFP13693.1 - 0.0059 15.7 0.1 0.09 11.8 0.1 2.6 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 V-set PF07686.17 KFP13696.1 - 1.1e-14 54.5 0.2 4.3e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP13696.1 - 7.4e-12 45.7 0.1 2.6e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP13696.1 - 3.9e-09 36.4 0.3 0.00028 20.9 0.0 2.8 2 2 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP13696.1 - 1.2e-08 35.0 1.8 6.3e-05 23.1 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFP13696.1 - 9.5e-08 32.3 0.2 8e-05 22.9 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_2 PF13895.6 KFP13696.1 - 9.5e-07 29.1 0.3 0.043 14.1 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP13696.1 - 1.1e-05 25.4 0.1 1.9e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFP13696.1 - 7e-05 22.8 0.2 0.00019 21.4 0.1 1.7 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFP13696.1 - 0.04 14.1 0.1 0.096 12.9 0.1 1.6 1 1 0 1 1 1 0 Natural killer cell receptor 2B4 BAR_3 PF16746.5 KFP13697.1 - 2.4e-60 204.2 10.9 4.3e-60 203.4 10.9 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFP13697.1 - 1.3e-08 35.3 0.0 8.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 PH domain PID PF00640.23 KFP13697.1 - 2e-08 34.4 0.3 5.7e-08 32.9 0.3 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP13697.1 - 8.3e-06 26.0 0.2 1.9e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.6 KFP13697.1 - 0.004 17.5 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 KFP13697.1 - 0.0049 17.2 0.0 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 Plant pleckstrin homology-like region DUF3263 PF11662.8 KFP13697.1 - 0.03 14.1 0.2 0.092 12.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) PH_17 PF18012.1 KFP13697.1 - 0.076 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 KFP13697.1 - 0.16 12.3 0.1 3.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain RhoGAP PF00620.27 KFP13698.1 - 2.8e-45 153.8 0.1 6.5e-45 152.7 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain RPEL PF02755.15 KFP13698.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 RPEL repeat PX PF00787.24 KFP13698.1 - 0.055 13.4 0.0 0.24 11.4 0.0 2.2 1 0 0 1 1 1 0 PX domain Cpn10 PF00166.21 KFP13699.1 - 1.5e-16 60.2 0.9 1.6e-16 60.1 0.9 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit C2-set_2 PF08205.12 KFP13700.1 - 7.7e-09 35.5 0.2 1.6e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFP13700.1 - 3.2e-07 30.3 0.1 0.019 15.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13700.1 - 4.1e-05 24.1 3.3 0.097 13.3 0.1 2.8 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFP13700.1 - 0.00049 20.2 0.9 0.0028 17.8 0.1 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain DUF3169 PF11368.8 KFP13700.1 - 0.0048 16.5 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Orf78 PF06024.12 KFP13700.1 - 0.0093 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Orf78 (ac78) ig PF00047.25 KFP13700.1 - 0.019 15.1 3.5 1.5 9.0 0.1 3.2 3 0 0 3 3 3 0 Immunoglobulin domain TMEM154 PF15102.6 KFP13700.1 - 0.048 13.6 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family SH3_9 PF14604.6 KFP13701.1 - 1e-17 63.7 0.0 2.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain His_Phos_1 PF00300.22 KFP13701.1 - 4.1e-17 62.5 0.0 1.2e-16 61.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2_5_RNA_ligase2 PF13563.6 KFP13701.1 - 3.7e-06 26.9 0.9 9e-06 25.7 0.4 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SH3_1 PF00018.28 KFP13701.1 - 4.5e-05 23.0 0.0 9.4e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.16 KFP13701.1 - 5.8e-05 23.2 0.1 0.36 11.0 0.1 2.7 3 0 0 3 3 3 2 LigT like Phosphoesterase His_Phos_2 PF00328.22 KFP13701.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) 7tm_4 PF13853.6 KFP13702.1 - 1e-43 150.1 13.8 1.2e-43 149.9 13.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP13702.1 - 1.8e-29 102.9 12.9 2.4e-29 102.5 12.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF423 PF04241.15 KFP13702.1 - 0.015 15.5 1.9 0.08 13.2 1.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF423) 7TM_GPCR_Srsx PF10320.9 KFP13702.1 - 0.027 13.8 9.8 0.046 13.1 9.8 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx PDZ PF00595.24 KFP13703.1 - 1.6e-45 153.4 6.7 3.8e-16 59.2 0.2 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFP13703.1 - 9.7e-24 83.0 2.9 9.8e-07 28.5 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFP13703.1 - 7.7e-16 58.2 2.1 0.0004 20.6 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 KFP13703.1 - 1.3e-12 47.8 0.1 2.7e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KFP13703.1 - 1.2e-08 34.5 0.5 1.4e-07 31.1 0.0 3.1 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.28 KFP13703.1 - 0.00022 20.8 0.0 0.0032 17.0 0.0 2.9 2 0 0 2 2 2 1 SH3 domain Frataxin_Cyay PF01491.16 KFP13704.1 - 4.4e-37 126.5 0.0 5.3e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain ORF_12_N PF18042.1 KFP13704.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ORF 12 gene product N-terminal PIP5K PF01504.18 KFP13705.1 - 1.8e-92 309.5 0.1 2.3e-92 309.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Flavokinase PF01687.17 KFP13707.1 - 2.3e-23 82.6 0.0 2.6e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF3248 PF11609.8 KFP13707.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Peptidase_S8 PF00082.22 KFP13708.1 - 1e-49 169.4 3.7 1.6e-49 168.8 3.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP13708.1 - 2.8e-31 107.4 0.0 5.3e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.6 KFP13708.1 - 6.7e-14 51.8 90.5 3e-09 36.8 41.5 3.9 1 1 2 3 3 3 3 Growth factor receptor domain IV PLAC PF08686.11 KFP13708.1 - 1.3e-12 48.3 7.4 1.3e-12 48.3 7.4 4.8 5 0 0 5 5 5 1 PLAC (protease and lacunin) domain S8_pro-domain PF16470.5 KFP13708.1 - 3.1e-12 47.1 0.5 6.2e-12 46.1 0.5 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Furin-like_2 PF15913.5 KFP13708.1 - 3.5e-12 46.4 72.1 6.7e-06 26.2 20.2 4.7 1 1 2 3 3 3 3 Furin-like repeat, cysteine-rich VSP PF03302.13 KFP13708.1 - 2.2e-07 30.1 80.3 0.00091 18.2 16.1 5.6 2 1 4 6 6 6 4 Giardia variant-specific surface protein DUF4215 PF13948.6 KFP13708.1 - 0.021 15.2 16.0 0.021 15.2 16.0 7.1 5 2 1 6 6 6 0 Domain of unknown function (DUF4215) Ank_2 PF12796.7 KFP13710.1 - 2.1e-25 89.1 2.9 5.1e-17 62.2 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP13710.1 - 1.8e-22 79.1 6.1 3.1e-09 36.9 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP13710.1 - 2.7e-16 59.7 0.8 9e-08 32.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFP13710.1 - 1e-14 53.8 0.0 2.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 KFP13710.1 - 3.7e-14 52.4 0.4 8.6e-06 26.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat SH3_9 PF14604.6 KFP13710.1 - 1.2e-12 47.5 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP13710.1 - 2.2e-12 46.4 0.0 4.5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KFP13710.1 - 9.7e-11 40.9 0.3 0.012 16.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat AAA_18 PF13238.6 KFP13711.1 - 2e-14 54.2 0.0 6e-14 52.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFP13711.1 - 0.006 16.7 0.0 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 KFP13711.1 - 0.037 13.9 0.3 0.2 11.5 0.3 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 KFP13711.1 - 0.089 12.9 0.1 2.2 8.4 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase N2227 PF07942.12 KFP13712.1 - 4.5e-112 373.7 0.3 5.9e-112 373.3 0.3 1.1 1 0 0 1 1 1 1 N2227-like protein FH2 PF02181.23 KFP13712.1 - 0.0041 16.3 0.1 0.0091 15.2 0.0 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Methyltransf_11 PF08241.12 KFP13712.1 - 0.03 15.0 0.0 0.07 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RhoGAP PF00620.27 KFP13712.1 - 0.031 14.1 1.1 0.89 9.4 0.3 2.3 1 1 1 2 2 2 0 RhoGAP domain Methyltransf_12 PF08242.12 KFP13712.1 - 0.033 14.9 0.0 0.11 13.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFP13712.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LSDAT_euk PF18139.1 KFP13714.1 - 3.3e-120 400.5 0.2 4.6e-120 400.0 0.2 1.2 1 0 0 1 1 1 1 SLOG in TRPM Alpha_kinase PF02816.18 KFP13714.1 - 1.1e-43 149.6 0.0 3.3e-43 148.0 0.0 1.9 1 0 0 1 1 1 1 Alpha-kinase family TRPM_tetra PF16519.5 KFP13714.1 - 6.6e-26 90.2 2.3 6.6e-26 90.2 2.3 2.2 2 0 0 2 2 2 1 Tetramerisation domain of TRPM LSDAT_prok PF18171.1 KFP13714.1 - 1.7e-15 56.8 0.2 3e-15 56.0 0.2 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFP13714.1 - 1.8e-13 50.3 15.8 3.3e-13 49.4 15.8 1.4 1 0 0 1 1 1 1 Ion transport protein Tmemb_18A PF09771.9 KFP13714.1 - 0.089 13.2 2.9 7.2 7.0 0.2 3.3 2 1 1 3 3 3 0 Transmembrane protein 188 zf-C4 PF00105.18 KFP13715.1 - 2.3e-33 114.5 12.3 5.4e-33 113.3 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP13715.1 - 6e-24 84.8 1.9 6e-24 84.8 1.9 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor RVT_1 PF00078.27 KFP13717.1 - 0.002 17.7 0.0 0.0048 16.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4462 PF14692.6 KFP13718.1 - 0.11 12.0 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Annexin PF00191.20 KFP13721.1 - 1.3e-84 278.3 13.9 9.2e-23 80.1 0.7 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFP13721.1 - 0.00063 19.6 2.7 0.66 9.9 0.0 3.5 2 1 1 3 3 3 1 Myb DNA-binding like DrrA_P4M PF14860.6 KFP13721.1 - 0.021 14.6 4.3 2.2 8.2 0.9 3.1 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain GT-D PF08759.11 KFP13721.1 - 0.06 13.0 1.2 0.2 11.3 0.3 2.0 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold Ribosomal_S17 PF00366.20 KFP13721.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S17 TPR_1 PF00515.28 KFP13721.1 - 0.15 12.0 0.5 7.3 6.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_11 PF13720.6 KFP13721.1 - 0.98 9.9 3.1 4.5 7.8 0.3 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_2 PF07719.17 KFP13721.1 - 3.7 7.9 5.9 12 6.3 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Aldedh PF00171.22 KFP13722.1 - 1.9e-178 593.8 0.0 2.1e-178 593.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFP13722.1 - 0.13 11.7 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) zf-A20 PF01754.16 KFP13723.1 - 8.1e-13 48.1 8.7 2.6e-12 46.4 8.7 2.0 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KFP13723.1 - 1.9e-09 37.5 8.2 1.9e-09 37.5 8.2 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger FAM53 PF15242.6 KFP13723.1 - 0.093 12.5 12.1 0.13 12.1 12.1 1.1 1 0 0 1 1 1 0 Family of FAM53 DUF2039 PF10217.9 KFP13724.1 - 1.3e-24 86.4 11.6 1.4e-24 86.2 11.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 KFP13724.1 - 0.0008 19.9 7.1 0.0008 19.9 7.1 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 KFP13724.1 - 0.0017 18.3 8.3 0.0025 17.8 8.3 1.2 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KFP13724.1 - 0.18 11.8 9.5 13 5.9 9.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon Hydrolase_4 PF12146.8 KFP13725.1 - 3.8e-13 49.3 0.0 3.8e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP13725.1 - 6.7e-08 33.4 0.0 4.1e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP13725.1 - 9.4e-08 32.0 0.1 0.0027 17.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP13725.1 - 1.6e-07 31.1 0.0 2.1e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFP13725.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KFP13725.1 - 0.0023 17.9 0.0 0.054 13.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KFP13725.1 - 0.0036 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KFP13725.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Asp2 PF16929.5 KFP13725.1 - 0.0045 16.0 0.0 0.0063 15.5 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter DUF818 PF05677.12 KFP13725.1 - 0.0046 16.0 0.1 0.0064 15.5 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KFP13725.1 - 0.026 14.3 0.0 0.26 11.1 0.0 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ILEI PF15711.5 KFP13726.1 - 4.5e-36 123.2 0.0 2.8e-20 72.6 0.0 3.3 3 0 0 3 3 3 2 Interleukin-like EMT inducer G8 PF10162.9 KFP13726.1 - 5.6e-26 91.0 0.0 1.2e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 G8 domain PADR1 PF08063.12 KFP13726.1 - 0.082 12.7 0.6 12 5.7 0.1 2.9 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-H2C2_2 PF13465.6 KFP13727.1 - 5.3e-48 159.4 128.1 1.9e-06 28.0 2.3 15.7 16 0 0 16 16 16 14 Zinc-finger double domain zf-C2H2 PF00096.26 KFP13727.1 - 4.8e-47 155.9 137.8 0.00013 22.2 1.3 14.8 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP13727.1 - 1.1e-35 119.2 131.8 0.0051 17.5 2.8 14.7 14 0 0 14 14 14 14 C2H2-type zinc finger BTB PF00651.31 KFP13727.1 - 4.9e-21 75.0 0.5 1.3e-20 73.7 0.5 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.7 KFP13727.1 - 7.7e-10 38.8 84.5 0.00045 20.5 1.4 13.9 14 0 0 14 14 14 5 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP13727.1 - 6.5e-08 32.4 118.7 0.019 14.9 2.9 13.7 14 0 0 14 14 14 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP13727.1 - 5e-06 26.7 88.2 0.027 14.8 2.5 13.8 14 0 0 14 14 14 5 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP13727.1 - 0.0064 16.4 8.1 0.01 15.7 2.8 12.3 14 0 0 14 14 13 3 zinc-finger of a C2HC-type GAGA PF09237.11 KFP13727.1 - 0.01 15.7 15.8 4.9 7.0 0.1 6.6 3 2 3 6 6 6 2 GAGA factor zf-C2H2_2 PF12756.7 KFP13727.1 - 0.067 13.5 0.1 0.067 13.5 0.1 13.0 3 1 8 12 12 12 0 C2H2 type zinc-finger (2 copies) SDA1 PF05285.12 KFP13727.1 - 0.074 12.5 15.9 0.19 11.1 15.9 1.7 1 0 0 1 1 1 0 SDA1 BolA PF01722.18 KFP13727.1 - 0.61 10.4 10.9 15 6.0 0.1 5.1 3 2 2 5 5 5 0 BolA-like protein Thioredoxin_2 PF13098.6 KFP13727.1 - 4 7.9 6.7 1 9.9 1.7 2.7 2 0 0 2 2 1 0 Thioredoxin-like domain EGF PF00008.27 KFP13728.1 - 1.8e-90 296.7 278.2 1.5e-07 31.6 7.3 20.1 19 1 0 19 19 19 17 EGF-like domain Laminin_G_2 PF02210.24 KFP13728.1 - 8.6e-51 171.8 0.8 6.5e-21 75.2 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain hEGF PF12661.7 KFP13728.1 - 6.8e-49 162.9 227.3 1.3e-05 25.6 2.1 20.6 20 0 0 20 20 20 17 Human growth factor-like EGF Laminin_G_1 PF00054.23 KFP13728.1 - 6.6e-38 129.9 0.3 2.3e-14 53.8 0.0 3.7 4 0 0 4 4 4 3 Laminin G domain EGF_CA PF07645.15 KFP13728.1 - 6.6e-17 61.4 270.1 1.3e-05 25.2 6.2 20.0 16 3 4 20 20 20 12 Calcium-binding EGF domain EGF_2 PF07974.13 KFP13728.1 - 1.2e-11 44.7 294.9 0.027 14.8 11.7 19.2 18 1 0 18 18 18 13 EGF-like domain Laminin_G_3 PF13385.6 KFP13728.1 - 9.2e-06 25.9 0.0 0.14 12.3 0.0 3.5 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily cEGF PF12662.7 KFP13728.1 - 0.0028 17.5 4.3 0.0028 17.5 4.3 17.7 17 2 1 18 18 18 8 Complement Clr-like EGF-like DENN PF02141.21 KFP13729.1 - 9.2e-49 165.9 3.8 1.5e-48 165.2 3.8 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KFP13729.1 - 3.7e-10 39.6 1.9 7.2e-10 38.7 1.0 2.0 2 0 0 2 2 2 1 dDENN domain Pkinase PF00069.25 KFP13732.1 - 1e-65 221.8 0.0 1.3e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP13732.1 - 3.8e-48 164.0 0.0 4.7e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP13732.1 - 6.7e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP13732.1 - 1.7e-05 23.9 0.0 3.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP13732.1 - 0.00026 19.9 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFP13732.1 - 0.0039 16.9 0.3 0.22 11.1 0.1 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kdo PF06293.14 KFP13732.1 - 0.0052 16.2 0.1 0.0082 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF309 PF03745.14 KFP13732.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Gln_deamidase_2 PF18626.1 KFP13732.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaminase APH PF01636.23 KFP13732.1 - 0.16 11.8 0.0 0.59 10.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family V-ATPase_G PF03179.15 KFP13733.1 - 6.2e-30 103.8 8.1 7e-30 103.7 8.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KFP13733.1 - 0.051 13.0 10.5 0.076 12.4 10.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Wx5_PLAF3D7 PF09688.10 KFP13733.1 - 0.1 12.6 2.9 0.13 12.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) OmpH PF03938.14 KFP13733.1 - 0.33 11.3 7.7 0.41 11.0 7.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Gti1_Pac2 PF09729.9 KFP13733.1 - 0.45 10.6 4.7 0.52 10.4 4.7 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Rib_recp_KP_reg PF05104.12 KFP13733.1 - 4.2 8.4 9.6 4.7 8.2 9.6 1.3 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region Y_phosphatase PF00102.27 KFP13734.1 - 4.9e-159 527.0 1.6 2.8e-82 275.8 0.0 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP13734.1 - 2.1e-07 31.2 10.0 0.00014 22.1 0.6 5.3 5 0 0 5 5 5 2 Fibronectin type III domain Y_phosphatase3 PF13350.6 KFP13734.1 - 1.4e-06 28.4 0.1 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP13734.1 - 0.00018 21.7 0.0 0.52 10.4 0.0 3.7 4 0 0 4 4 4 2 Inositol hexakisphosphate DSPc PF00782.20 KFP13734.1 - 0.0035 17.2 0.0 0.09 12.6 0.0 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KFP13734.1 - 0.024 14.2 0.0 7.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Tissue_fac PF01108.17 KFP13734.1 - 0.026 14.4 0.3 0.026 14.4 0.3 2.7 3 0 0 3 3 3 0 Tissue factor Anti-adapt_IraP PF10796.9 KFP13734.1 - 0.089 13.4 0.1 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein zf-C4 PF00105.18 KFP13739.1 - 2.8e-32 111.0 12.0 4.8e-32 110.2 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP13739.1 - 7e-31 107.4 5.7 1.1e-30 106.7 5.7 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF2431 PF10354.9 KFP13739.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) zf-H2C2_2 PF13465.6 KFP13740.1 - 1.9e-19 69.1 20.9 1.4e-06 28.4 0.2 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP13740.1 - 5.1e-12 45.5 33.4 0.0024 18.2 0.8 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP13740.1 - 9.2e-07 29.2 42.5 0.01 16.6 4.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger FYVE PF01363.21 KFP13740.1 - 3.6e-06 27.0 0.2 0.12 12.6 0.0 3.1 1 1 1 2 2 2 1 FYVE zinc finger DZR PF12773.7 KFP13740.1 - 1.4 9.0 8.0 6.5 6.9 2.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon GAGA PF09237.11 KFP13740.1 - 1.4 8.7 9.6 0.16 11.8 1.8 2.9 1 1 1 3 3 3 0 GAGA factor XPA_N PF01286.18 KFP13740.1 - 2.1 8.5 9.0 9.6 6.3 0.0 4.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_jaz PF12171.8 KFP13740.1 - 3.6 8.0 16.8 2.8 8.3 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 KFP13740.1 - 6 6.6 12.9 0.59 9.8 1.8 3.2 2 1 1 3 3 3 0 MYST family zinc finger domain Kinesin PF00225.23 KFP13741.1 - 1.9e-107 359.0 0.1 1.9e-107 359.0 0.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP13741.1 - 2.8e-25 89.0 3.1 3e-25 88.9 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KFP13741.1 - 1e-13 51.9 7.3 8.8e-12 45.5 1.0 4.3 3 2 1 4 4 4 2 Kinesin-associated FHA PF00498.26 KFP13741.1 - 2.6e-08 34.1 0.2 6.4e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 KFP13741.1 - 0.0057 17.1 1.6 0.064 13.7 0.1 3.0 2 0 0 2 2 2 1 Kinesin protein 1B DUF4951 PF16309.5 KFP13741.1 - 0.051 13.6 0.3 0.19 11.8 0.3 2.0 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) AAA_16 PF13191.6 KFP13741.1 - 0.98 9.8 3.2 4.9 7.5 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain FAM184 PF15665.5 KFP13741.1 - 1.9 8.2 39.8 0.58 9.9 25.4 2.6 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B PID PF00640.23 KFP13741.1 - 2.6 8.1 7.9 1.3 9.1 4.2 2.5 1 1 1 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) DEAD PF00270.29 KFP13742.1 - 8.4e-44 149.4 2.3 1e-43 149.1 0.7 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP13742.1 - 1.6e-21 76.7 0.0 5.4e-20 71.8 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 KFP13742.1 - 4.1e-08 33.0 1.7 6.9e-08 32.2 1.7 1.4 1 0 0 1 1 1 1 HIT zinc finger SecA_DEAD PF07517.14 KFP13742.1 - 0.011 15.1 0.1 0.39 10.0 0.0 2.5 2 0 0 2 2 2 0 SecA DEAD-like domain CMS1 PF14617.6 KFP13742.1 - 0.052 12.9 0.1 0.15 11.4 0.1 1.8 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 KFP13742.1 - 0.06 13.8 0.5 0.31 11.5 0.2 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFP13742.1 - 0.07 12.6 1.4 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Toprim_C_rpt PF13368.6 KFP13742.1 - 0.082 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat CAMSAP_CKK PF08683.11 KFP13743.1 - 3.2e-54 182.2 0.1 6e-54 181.3 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 KFP13743.1 - 2.1e-36 123.6 2.0 5.6e-36 122.2 2.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFP13743.1 - 1.1e-24 86.0 4.9 1.1e-24 86.0 4.9 3.1 3 0 0 3 3 3 1 Spectrin-binding region of Ca2+-Calmodulin CH PF00307.31 KFP13743.1 - 0.034 14.3 0.0 0.18 12.0 0.0 2.3 1 0 0 1 1 1 0 Calponin homology (CH) domain WD40 PF00400.32 KFP13744.1 - 5.2e-28 96.7 15.0 2.7e-05 24.8 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13744.1 - 5.3e-13 49.1 0.0 8.9e-05 22.7 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KFP13744.1 - 4.6e-09 35.8 1.4 2.3e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 LisH-like dimerisation domain Vir_act_alpha_C PF10400.9 KFP13744.1 - 0.19 12.5 5.4 0.44 11.3 5.4 1.6 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF4798 PF16055.5 KFP13744.1 - 1.6 9.0 4.7 22 5.3 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4798) Acetyltransf_1 PF00583.25 KFP13745.1 - 2.7e-11 43.7 0.0 4.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP13745.1 - 7.2e-10 38.9 0.1 9.8e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP13745.1 - 1.1e-08 34.9 0.1 1.5e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFP13745.1 - 4.1e-08 33.5 0.0 5.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP13745.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MutS_V PF00488.21 KFP13746.1 - 1.2e-72 243.9 0.3 2.6e-72 242.8 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFP13746.1 - 3.7e-34 118.6 1.9 1.1e-32 113.8 0.9 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KFP13746.1 - 2.2e-19 70.1 0.3 5.7e-19 68.8 0.3 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFP13746.1 - 1.6e-15 57.2 0.0 4.1e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 KFP13746.1 - 2.1e-05 24.5 1.4 0.00078 19.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP13746.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFP13746.1 - 0.07 13.0 0.5 0.57 10.0 0.5 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KFP13746.1 - 0.091 13.2 1.8 0.18 12.3 0.1 2.4 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 KFP13746.1 - 0.097 12.9 0.1 0.61 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP13746.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KFP13746.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prenyltrans PF00432.21 KFP13747.1 - 1.7e-69 229.2 10.7 5.9e-15 54.7 0.2 5.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFP13747.1 - 0.00047 19.4 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFP13747.1 - 0.024 13.7 0.0 4.3 6.4 0.0 3.3 2 2 2 4 4 4 0 Squalene-hopene cyclase N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFP13748.1 - 5.9e-40 136.9 3.3 8.5e-40 136.4 3.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFP13748.1 - 8.4e-28 96.4 0.0 1.6e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFP13748.1 - 1.3e-26 93.5 0.1 2.5e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFP13748.1 - 3.6e-19 69.4 4.1 5.4e-19 68.8 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFP13748.1 - 5.6e-05 22.9 0.0 0.00021 21.0 0.0 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Choline_transpo PF04515.12 KFP13749.1 - 1.6e-112 375.9 34.7 1.6e-112 375.9 34.7 2.6 3 0 0 3 3 3 2 Plasma-membrane choline transporter TYW3 PF02676.14 KFP13751.1 - 1.6e-30 106.1 0.1 1.7e-30 106.0 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 RRXRR PF14239.6 KFP13751.1 - 0.021 14.7 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 RRXRR protein ADH_zinc_N PF00107.26 KFP13752.1 - 2.2e-22 79.4 0.9 4.5e-22 78.4 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP13752.1 - 4e-17 63.5 0.0 6.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP13752.1 - 2.2e-12 46.8 0.1 1.1e-11 44.5 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFP13752.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF4590 PF15257.6 KFP13753.1 - 5.2e-59 197.1 0.7 1.1e-58 196.1 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) Pkinase_Tyr PF07714.17 KFP13754.1 - 1.7e-57 194.7 0.0 2.6e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KFP13754.1 - 2.4e-53 178.6 21.9 4.8e-17 62.3 0.6 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP13754.1 - 6.1e-49 163.8 29.1 7.9e-11 42.3 0.0 8.1 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KFP13754.1 - 3.3e-47 156.9 30.3 3.1e-07 30.6 0.0 11.2 12 0 0 12 12 11 8 Ankyrin repeat Pkinase PF00069.25 KFP13754.1 - 3.5e-46 157.7 0.0 8.9e-46 156.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_3 PF13606.6 KFP13754.1 - 8.8e-40 130.2 22.2 0.00036 20.8 0.0 11.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KFP13754.1 - 1.3e-33 114.6 12.4 3.8e-06 27.1 0.1 9.1 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Kdo PF06293.14 KFP13754.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP13754.1 - 0.033 13.8 0.9 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KFP13754.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP13754.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SPATA24 PF15175.6 KFP13754.1 - 0.18 11.7 0.4 0.3 11.0 0.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 I-set PF07679.16 KFP13756.1 - 9.3e-35 118.6 0.2 3.9e-12 46.1 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13756.1 - 3.9e-34 117.1 0.6 2e-13 50.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP13756.1 - 6.4e-27 93.7 0.9 2.7e-10 40.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP13756.1 - 6.3e-24 84.0 0.6 2.4e-10 40.5 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 KFP13756.1 - 6.4e-13 48.8 4.1 1.5e-05 25.1 0.1 4.9 3 2 1 4 4 4 3 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP13756.1 - 3.7e-07 30.1 0.8 0.0012 18.8 0.1 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFP13756.1 - 1.2e-06 28.8 0.0 0.21 12.0 0.0 3.3 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP13756.1 - 2.8e-05 24.3 0.1 0.57 10.5 0.0 3.3 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP13756.1 - 0.00054 19.5 0.0 0.45 10.1 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KFP13756.1 - 0.00093 19.2 0.1 0.79 9.8 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFP13756.1 - 0.003 17.3 2.2 0.92 9.3 0.1 3.6 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFP13756.1 - 0.0069 16.4 0.1 0.12 12.4 0.0 2.8 3 1 0 3 3 3 1 C17orf99 Ig domain V-set_CD47 PF08204.11 KFP13756.1 - 0.012 15.6 0.1 7.7 6.5 0.1 2.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain zf-RanBP PF00641.18 KFP13757.1 - 1.7e-09 36.8 19.6 1.5e-06 27.4 9.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF35_N PF12172.8 KFP13757.1 - 0.027 14.3 7.6 1 9.3 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 KFP13757.1 - 4 7.5 8.8 8.3 6.5 2.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.15 KFP13757.1 - 4.8 6.8 7.4 0.8 9.3 1.1 2.3 2 0 0 2 2 2 0 RecR protein 7tm_1 PF00001.21 KFP13758.1 - 8.2e-12 45.0 5.1 1e-11 44.7 5.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cys_Met_Meta_PP PF01053.20 KFP13759.1 - 6.4e-147 489.1 0.0 7.2e-147 488.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFP13759.1 - 1.2e-06 28.0 0.1 1.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFP13759.1 - 3.2e-06 26.3 0.1 4.8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFP13759.1 - 6.5e-06 25.7 0.0 7.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 KFP13759.1 - 0.00027 19.9 0.0 0.00041 19.3 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein GPCR_chapero_1 PF11904.8 KFP13760.1 - 2e-66 224.5 0.5 4.1e-66 223.5 0.5 1.4 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 KFP13760.1 - 1.3e-08 35.3 0.1 2.8e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP13760.1 - 1.7e-08 34.8 0.1 3.2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP13760.1 - 1.8e-08 34.4 0.3 3.3e-06 27.3 0.8 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KFP13760.1 - 6e-08 32.4 0.1 0.0013 19.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFP13760.1 - 5.7e-05 23.3 0.1 0.00011 22.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) LRR_8 PF13855.6 KFP13762.1 - 1.8e-52 174.9 62.4 1.8e-12 46.8 9.7 8.4 5 2 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KFP13762.1 - 6.7e-45 150.3 76.5 1.2e-08 35.1 0.7 11.9 3 3 11 15 15 15 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP13762.1 - 3e-11 43.1 33.9 0.00069 19.2 2.7 6.1 2 2 4 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 KFP13762.1 - 6.6e-11 41.2 54.8 0.15 12.7 0.2 15.6 17 1 0 17 17 17 4 Leucine Rich Repeat LRR_6 PF13516.6 KFP13762.1 - 7.7 6.9 65.0 0.84 9.9 0.9 14.0 17 0 0 17 17 17 0 Leucine Rich repeat LRR_8 PF13855.6 KFP13763.1 - 1.6e-35 120.7 41.5 6.5e-09 35.4 0.7 6.9 2 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP13763.1 - 3.2e-29 100.5 47.8 4.8e-05 23.6 1.7 9.4 8 1 1 9 9 9 9 Leucine Rich repeats (2 copies) PDZ PF00595.24 KFP13763.1 - 1.7e-16 60.3 0.0 3.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP13763.1 - 2.8e-06 27.1 0.0 5.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 KFP13763.1 - 8.6e-06 25.7 1.0 0.018 15.0 0.1 3.9 2 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) PDZ_2 PF13180.6 KFP13763.1 - 4.6e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LRR_1 PF00560.33 KFP13763.1 - 0.077 13.6 39.7 6 7.8 0.1 11.9 11 2 0 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 KFP13763.1 - 0.15 12.2 19.3 2.4 8.5 0.1 7.3 8 1 1 9 9 9 0 Leucine Rich repeat DEP PF00610.21 KFP13765.1 - 8.4e-18 64.2 0.1 3.1e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KFP13765.1 - 0.00013 21.8 7.1 0.15 11.8 0.2 4.0 5 0 0 5 5 5 2 RhoGAP domain Beta_lactamase3 PF17030.5 KFP13765.1 - 0.03 13.6 0.4 0.06 12.6 0.4 1.4 1 0 0 1 1 1 0 Putative beta-lactamase-like family RPE65 PF03055.15 KFP13766.1 - 1.7e-117 393.4 0.2 2e-117 393.3 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MIG-14_Wnt-bd PF06664.12 KFP13767.1 - 9.5e-95 317.2 21.3 1.4e-94 316.6 21.3 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Ras PF00071.22 KFP13768.1 - 5.6e-47 159.4 0.1 6.8e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13768.1 - 2.7e-17 63.1 0.1 5.9e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP13768.1 - 3e-07 30.0 0.0 4.8e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP13768.1 - 3.2e-05 23.9 0.7 0.19 11.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP13768.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP13768.1 - 0.00056 19.4 1.3 0.003 17.0 1.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP13768.1 - 0.0022 17.6 0.1 0.008 15.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFP13768.1 - 0.014 14.4 0.2 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFP13768.1 - 0.016 15.6 0.1 0.023 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFP13768.1 - 0.017 15.4 0.1 0.059 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP13768.1 - 0.029 13.9 0.1 0.18 11.3 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFP13768.1 - 0.036 13.8 0.6 0.11 12.1 0.0 2.1 2 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KFP13768.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KFP13768.1 - 0.082 12.9 0.1 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 KFP13769.1 - 5.6e-47 159.4 0.1 6.8e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP13769.1 - 2.7e-17 63.1 0.1 5.9e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP13769.1 - 3e-07 30.0 0.0 4.8e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP13769.1 - 3.2e-05 23.9 0.7 0.19 11.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP13769.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP13769.1 - 0.00056 19.4 1.3 0.003 17.0 1.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP13769.1 - 0.0022 17.6 0.1 0.008 15.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFP13769.1 - 0.014 14.4 0.2 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFP13769.1 - 0.016 15.6 0.1 0.023 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFP13769.1 - 0.017 15.4 0.1 0.059 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP13769.1 - 0.029 13.9 0.1 0.18 11.3 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFP13769.1 - 0.036 13.8 0.6 0.11 12.1 0.0 2.1 2 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KFP13769.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KFP13769.1 - 0.082 12.9 0.1 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-gamma PF00631.22 KFP13771.1 - 7.7e-18 64.3 0.1 8.9e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 GGL domain CP12 PF02672.15 KFP13771.1 - 0.032 15.0 0.0 0.046 14.5 0.0 1.2 1 0 0 1 1 1 0 CP12 domain HABP4_PAI-RBP1 PF04774.15 KFP13772.1 - 2.6e-32 112.1 11.5 2.6e-32 112.1 11.5 1.9 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family IHABP4_N PF16174.5 KFP13772.1 - 4.4e-07 30.7 9.9 4.4e-07 30.7 9.9 2.5 2 1 0 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal TPT PF03151.16 KFP13775.1 - 1.1e-10 41.4 9.5 1.3e-10 41.2 9.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP13775.1 - 0.00017 21.7 17.7 0.0053 16.9 8.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFP13775.1 - 0.0035 16.3 0.9 0.0035 16.3 0.9 2.1 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF2070 PF09843.9 KFP13775.1 - 0.071 11.4 8.5 0.088 11.1 8.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UAA PF08449.11 KFP13775.1 - 0.099 11.8 15.5 0.13 11.4 15.5 1.2 1 0 0 1 1 1 0 UAA transporter family ELM2 PF01448.24 KFP13776.1 - 8.4e-12 45.7 2.4 9.5e-11 42.3 0.0 3.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP13776.1 - 4.2e-07 30.0 0.1 9.5e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP13776.1 - 0.0049 16.7 0.8 0.02 14.8 0.0 2.5 2 0 0 2 2 2 1 Myb DNA-binding like Insulin PF00049.18 KFP13778.1 - 0.047 14.7 0.0 0.082 13.9 0.0 1.4 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family Tctex-1 PF03645.13 KFP13779.1 - 2.2e-25 88.9 0.0 2.4e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family muHD PF10291.9 KFP13780.1 - 6.8e-67 225.7 0.0 9.4e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 KFP13780.1 - 1.5e-06 27.8 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Atg29_N PF18388.1 KFP13780.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Atg29 N-terminal domain ObR_Ig PF18589.1 KFP13782.1 - 6.7e-75 248.2 11.4 2.9e-39 133.7 3.6 3.2 3 0 0 3 3 3 2 Obesity receptor immunoglobulin like domain Lep_receptor_Ig PF06328.11 KFP13782.1 - 1e-24 86.2 0.4 1e-24 86.2 0.4 2.6 3 0 0 3 3 3 1 Ig-like C2-type domain fn3 PF00041.21 KFP13782.1 - 1.4e-11 44.6 7.9 0.0027 18.0 0.1 4.9 4 0 0 4 4 4 3 Fibronectin type III domain Vps55 PF04133.14 KFP13783.1 - 4.1e-39 133.2 6.6 4.6e-39 133.0 6.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 PTEN_C2 PF10409.9 KFP13784.1 - 3.2e-28 98.2 0.0 6.9e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.31 KFP13784.1 - 2e-06 27.8 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.27 KFP13784.1 - 0.0085 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ADK_lid PF05191.14 KFP13785.1 - 1.5e-16 60.0 0.0 3.2e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Adenylate kinase, active site lid ADK PF00406.22 KFP13785.1 - 2.5e-15 56.9 0.0 3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase RRM_1 PF00076.22 KFP13786.1 - 3.7e-26 90.8 3.8 5.2e-14 51.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP13786.1 - 0.0014 18.4 0.0 2.1 8.3 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP13786.1 - 0.051 13.2 0.7 16 5.1 0.0 3.6 3 1 1 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KFP13786.1 - 0.13 12.2 0.2 10 6.2 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_3 PF08777.11 KFP13786.1 - 0.24 11.5 0.6 2.1 8.5 0.1 2.6 3 0 0 3 3 3 0 RNA binding motif VWA_N PF08399.11 KFP13787.1 - 6.4e-22 78.3 0.1 6.4e-19 68.6 0.0 3.3 2 1 0 2 2 2 1 VWA N-terminal dCache_1 PF02743.18 KFP13787.1 - 1.6e-15 57.5 1.0 3.7e-09 36.7 0.0 3.1 3 0 0 3 3 3 2 Cache domain VWA PF00092.28 KFP13787.1 - 6.2e-07 29.8 1.6 1.2e-06 28.9 1.6 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP13787.1 - 1.2e-05 25.9 0.5 3.3e-05 24.5 0.5 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP13787.1 - 0.06 13.3 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Pkinase_Tyr PF07714.17 KFP13788.1 - 9.5e-92 306.9 0.0 1.2e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP13788.1 - 2.9e-42 144.9 0.0 4.3e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFP13788.1 - 5.2e-23 81.2 4.9 1.3e-22 79.9 4.9 1.8 1 0 0 1 1 1 1 Kringle domain I-set PF07679.16 KFP13788.1 - 1.8e-17 63.2 0.0 3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13788.1 - 2.8e-16 59.9 0.1 6.7e-16 58.7 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 KFP13788.1 - 2.8e-11 44.0 3.7 2.8e-11 44.0 3.7 2.2 2 0 0 2 2 2 1 Fz domain Ig_2 PF13895.6 KFP13788.1 - 1.5e-08 34.8 1.3 2.3e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP13788.1 - 1.3e-07 31.6 0.1 3.2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP13788.1 - 1.2e-05 25.4 0.4 0.00043 20.4 0.4 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Haspin_kinase PF12330.8 KFP13788.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 KFP13788.1 - 0.11 12.4 1.3 0.11 12.3 0.0 1.6 2 0 0 2 2 1 0 TMEM154 protein family C2-set_2 PF08205.12 KFP13788.1 - 1 9.4 3.6 0.39 10.8 0.2 2.1 2 1 0 2 2 1 0 CD80-like C2-set immunoglobulin domain PGM_PMM_I PF02878.16 KFP13789.1 - 7.3e-34 116.4 0.1 1.2e-33 115.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KFP13789.1 - 2e-31 108.5 0.0 3.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFP13789.1 - 7.9e-19 68.2 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFP13789.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain EF-hand_7 PF13499.6 KFP13790.1 - 4.2e-13 49.6 2.2 5.9e-08 33.0 0.4 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP13790.1 - 3.5e-10 38.7 3.7 0.003 17.0 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP13790.1 - 1.1e-08 34.3 3.4 0.00033 20.4 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFP13790.1 - 1.3e-07 31.3 6.7 0.00051 19.8 0.1 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP13790.1 - 8.7e-05 21.9 0.9 0.032 13.7 0.3 2.6 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.10 KFP13790.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF_assoc_2 PF08356.12 KFP13790.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 EF hand associated DUF3085 PF11284.8 KFP13790.1 - 0.043 14.1 0.0 2.3 8.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3085) UPF0154 PF03672.13 KFP13790.1 - 0.061 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 KFP13790.1 - 0.099 12.6 1.1 4.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand CENP-R PF06729.12 KFP13791.1 - 5.5e-61 204.5 5.5 6.5e-61 204.3 5.5 1.0 1 0 0 1 1 1 1 Kinetochore component, CENP-R ORC6 PF05460.13 KFP13791.1 - 1.9 7.7 7.9 4.2 6.5 7.9 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Peptidase_C54 PF03416.19 KFP13792.1 - 9.7e-107 356.5 0.0 1.2e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DHR-2 PF06920.13 KFP13793.1 - 2.4e-212 706.3 4.0 2.4e-212 706.3 4.0 1.5 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP13793.1 - 4e-53 180.2 0.2 7.6e-53 179.2 0.2 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFP13793.1 - 4.3e-36 123.7 0.2 2.4e-34 118.1 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) DOCK_N PF16172.5 KFP13793.1 - 0.01 14.8 1.9 0.015 14.2 0.0 2.2 3 0 0 3 3 3 0 DOCK N-terminus TEA PF01285.18 KFP13793.1 - 0.095 12.8 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 TEA/ATTS domain Fibrinogen_C PF00147.18 KFP13794.1 - 2.1e-54 184.7 0.7 3.3e-54 184.0 0.7 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain UPF0242 PF06785.11 KFP13794.1 - 0.00039 20.6 17.2 0.00061 20.0 17.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KFP13794.1 - 0.042 12.9 5.6 0.059 12.5 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPX2 PF06886.11 KFP13794.1 - 0.35 11.1 2.9 0.85 9.9 2.9 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Med15_fungi PF05397.12 KFP13794.1 - 0.55 10.5 10.2 1.1 9.6 10.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 15 DUF1465 PF07323.12 KFP13794.1 - 0.6 9.9 4.5 0.59 10.0 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Spc29 PF17082.5 KFP13794.1 - 1.2 8.9 13.5 1 9.2 3.8 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 HrpB2 PF09487.10 KFP13794.1 - 1.3 9.5 6.5 1.4 9.4 0.6 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF1664 PF07889.12 KFP13794.1 - 1.8 8.6 12.9 0.26 11.3 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 KFP13794.1 - 4.7 7.0 10.6 5.8 6.7 2.1 2.2 2 0 0 2 2 2 0 USP8 interacting DUF4559 PF15112.6 KFP13794.1 - 8.9 5.9 16.2 14 5.3 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) UCH PF00443.29 KFP13795.1 - 2.2e-43 148.6 0.2 1.9e-37 129.2 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP13795.1 - 2.3e-15 57.0 13.9 8.1e-13 48.6 14.0 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ank_5 PF13857.6 KFP13797.1 - 7.9e-24 83.4 3.1 1.6e-14 53.8 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP13797.1 - 3.3e-23 82.1 1.0 9.2e-08 32.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP13797.1 - 9e-19 67.0 1.4 5.9e-05 23.3 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFP13797.1 - 5e-17 62.0 0.4 4.3e-08 33.5 0.0 3.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP13797.1 - 5.3e-17 60.2 0.4 0.00094 19.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat PDZ PF00595.24 KFP13798.1 - 3e-148 482.5 38.8 7.8e-18 64.6 0.1 10.4 10 0 0 10 10 10 10 PDZ domain PDZ_6 PF17820.1 KFP13798.1 - 4.2e-84 276.3 29.4 1.8e-10 40.5 0.6 10.4 10 0 0 10 10 10 10 PDZ domain PDZ_2 PF13180.6 KFP13798.1 - 3.1e-44 149.2 21.4 0.00021 21.5 0.0 10.7 10 0 0 10 10 10 10 PDZ domain L27_2 PF09045.10 KFP13798.1 - 3.3e-15 55.8 7.4 7.3e-15 54.7 7.4 1.6 1 0 0 1 1 1 1 L27_2 MPDZ_u10 PF16667.5 KFP13798.1 - 1.6e-05 25.7 1.1 1.6e-05 25.7 1.1 3.8 4 0 0 4 4 4 1 Unstructured region 10 on multiple PDZ protein L27_1 PF09058.10 KFP13798.1 - 3.6 7.6 11.3 0.057 13.4 3.1 2.4 3 0 0 3 3 3 0 L27_1 TM2 PF05154.16 KFP13799.1 - 4.5e-17 62.1 5.5 6.6e-17 61.6 5.5 1.2 1 0 0 1 1 1 1 TM2 domain Nitrate_red_gam PF02665.14 KFP13799.1 - 0.027 14.0 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit CTF_NFI PF00859.18 KFP13800.1 - 3.7e-118 394.7 24.6 4.4e-118 394.5 24.6 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Cadherin_3 PF16184.5 KFP13803.1 - 1.4e-10 41.2 0.0 1.4e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 Cadherin-like p450 PF00067.22 KFP13804.1 - 5e-10 38.7 0.5 5.1e-10 38.7 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP13805.1 - 5.6e-41 140.8 0.0 6.2e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP13806.1 - 1.4e-128 429.6 0.3 1.7e-128 429.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 HOOK PF05622.12 KFP13807.1 - 0 1023.2 80.1 0 1023.0 80.1 1.0 1 0 0 1 1 1 1 HOOK protein ATG16 PF08614.11 KFP13807.1 - 5e-06 26.9 90.2 0.23 11.7 13.9 5.4 1 1 4 5 5 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KFP13807.1 - 2.4e-05 23.4 15.2 2.4e-05 23.4 15.2 5.2 1 1 4 5 5 5 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFP13807.1 - 0.0014 18.7 21.8 0.0014 18.7 21.8 6.0 2 2 4 6 6 6 2 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 KFP13807.1 - 0.01 15.7 3.3 0.01 15.7 3.3 7.9 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Nup54 PF13874.6 KFP13807.1 - 0.013 15.7 5.0 0.013 15.7 5.0 5.1 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 YlmH_RBD PF17774.1 KFP13807.1 - 0.038 14.3 0.2 11 6.4 0.0 2.9 2 0 0 2 2 2 0 Putative RNA-binding domain in YlmH GAS PF13851.6 KFP13807.1 - 1.4 8.2 103.8 0.029 13.7 20.3 5.7 1 1 6 7 7 7 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KFP13807.1 - 3 8.2 83.7 7.7 6.9 11.2 4.6 1 1 3 4 4 4 0 Fez1 Laminin_II PF06009.12 KFP13807.1 - 3.7 7.6 55.5 0.44 10.6 3.5 5.7 2 2 2 5 5 5 0 Laminin Domain II zf-C3HC4 PF00097.25 KFP13808.1 - 7.2e-10 38.6 7.3 1.3e-09 37.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP13808.1 - 6.1e-09 35.6 4.0 1e-08 34.9 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP13808.1 - 8e-09 35.4 8.7 2.5e-08 33.8 8.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP13808.1 - 1e-08 35.2 8.5 2.1e-08 34.2 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP13808.1 - 8e-08 32.5 8.8 1.3e-07 31.8 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFP13808.1 - 1.3e-07 31.4 9.7 1.8e-06 27.7 1.6 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFP13808.1 - 6.4e-07 29.1 8.8 1.5e-06 27.9 8.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP13808.1 - 8.1e-06 25.7 7.6 0.00017 21.4 8.4 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 KFP13808.1 - 0.0053 16.6 3.3 0.011 15.5 3.3 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KFP13808.1 - 0.0079 16.2 5.4 0.057 13.5 1.3 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFP13808.1 - 0.11 12.3 5.0 0.37 10.6 2.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4020 PF13212.6 KFP13808.1 - 0.15 11.8 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) HypA PF01155.19 KFP13808.1 - 0.21 11.6 1.8 0.44 10.6 1.8 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_IE-1 PF05290.11 KFP13808.1 - 0.25 11.3 7.1 0.33 10.9 6.9 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Lar_restr_allev PF14354.6 KFP13808.1 - 0.32 11.4 5.0 2.8 8.4 1.0 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.13 KFP13808.1 - 0.37 10.9 6.8 6.9 6.8 5.9 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-rbx1 PF12678.7 KFP13808.1 - 0.41 11.0 12.3 0.11 12.7 9.0 1.8 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-Sec23_Sec24 PF04810.15 KFP13808.1 - 0.78 9.8 6.9 2.4 8.3 0.1 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.12 KFP13808.1 - 1.1 9.6 6.5 34 4.8 6.4 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KFP13808.1 - 2 8.7 6.8 5.7 7.3 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon TerY_C PF15616.6 KFP13808.1 - 2.5 8.2 6.4 8.5 6.5 6.4 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain FGGY_C PF02782.16 KFP13809.1 - 2.4e-47 161.3 0.1 3.6e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFP13809.1 - 1.5e-27 96.8 0.0 2.1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KFP13809.1 - 0.014 14.9 0.1 0.51 9.8 0.0 2.8 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Jun PF03957.13 KFP13810.1 - 7.2e-96 320.5 9.0 1e-95 320.1 9.0 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.21 KFP13810.1 - 7.8e-18 64.3 17.8 1.7e-17 63.2 17.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP13810.1 - 2.4e-09 37.2 14.4 6.2e-09 35.8 14.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP13810.1 - 7.6e-09 36.0 9.3 1.5e-08 35.0 9.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFP13810.1 - 0.00043 20.7 6.2 0.0018 18.7 3.6 2.4 2 0 0 2 2 2 1 Cell division protein ZapB PspA_IM30 PF04012.12 KFP13810.1 - 0.0073 15.9 5.7 0.0073 15.9 5.7 1.4 1 1 0 1 1 1 1 PspA/IM30 family Fib_alpha PF08702.10 KFP13810.1 - 0.01 16.0 1.0 0.017 15.3 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 KFP13810.1 - 0.02 15.1 7.1 0.035 14.3 7.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KFP13810.1 - 0.023 15.1 1.6 0.054 13.9 1.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KFP13810.1 - 0.046 14.0 0.9 0.17 12.2 0.9 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Spc29 PF17082.5 KFP13810.1 - 0.066 13.0 3.3 0.1 12.4 1.6 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF3450 PF11932.8 KFP13810.1 - 0.1 11.9 4.5 0.15 11.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 KFP13810.1 - 0.85 9.9 7.9 1.7 8.9 7.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KFP13810.1 - 1.1 9.3 4.8 1.9 8.5 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KFP13810.1 - 3.9 7.3 8.8 7.2 6.4 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 KFP13810.1 - 4 7.3 8.6 2.1 8.2 5.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Ank_2 PF12796.7 KFP13811.1 - 1.3e-82 272.4 32.7 8.6e-20 71.1 0.2 8.0 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP13811.1 - 1.4e-76 252.0 27.4 2.9e-12 46.9 0.0 12.1 5 3 8 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP13811.1 - 6e-74 235.1 20.7 2.6e-05 24.2 0.2 16.0 16 0 0 16 16 16 14 Ankyrin repeat Ank PF00023.30 KFP13811.1 - 9.4e-70 228.2 46.2 1.8e-06 28.2 1.0 16.0 14 2 2 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 KFP13811.1 - 1.5e-66 219.6 23.5 2e-10 40.7 0.1 12.6 3 2 10 13 13 13 12 Ankyrin repeats (many copies) DUF3447 PF11929.8 KFP13811.1 - 0.0034 17.3 0.0 6.2 6.9 0.0 4.1 6 0 0 6 6 6 1 Domain of unknown function (DUF3447) Mic1 PF07035.12 KFP13811.1 - 0.081 12.6 2.3 3.8 7.2 0.9 3.8 2 2 0 2 2 2 0 Colon cancer-associated protein Mic1-like DUF2520 PF10728.9 KFP13811.1 - 4.8 6.9 14.2 0.6 9.9 3.1 4.0 4 2 1 5 5 5 0 Domain of unknown function (DUF2520) SWIRM PF04433.17 KFP13812.1 - 1.1e-20 73.8 0.0 4.1e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain JAB PF01398.21 KFP13812.1 - 2.9e-12 46.6 0.0 6.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.31 KFP13812.1 - 3.5e-12 46.3 0.2 9.2e-12 45.0 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.6 KFP13812.1 - 1.1e-08 34.8 0.1 3.6e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 KFP13812.1 - 0.00011 22.3 0.6 0.00038 20.7 0.6 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.13 KFP13812.1 - 0.00086 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Myb_DNA-bind_7 PF15963.5 KFP13812.1 - 0.013 15.4 0.4 0.047 13.6 0.4 2.0 1 0 0 1 1 1 0 Myb DNA-binding like Peptidase_M48 PF01435.18 KFP13813.1 - 5.4e-31 107.9 0.0 7.7e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Sulf_transp PF04143.14 KFP13813.1 - 0.17 11.4 2.1 0.12 11.9 0.4 1.5 2 0 0 2 2 2 0 Sulphur transport Peptidase_U49 PF10463.9 KFP13813.1 - 0.35 10.6 2.0 1.3 8.8 2.0 2.0 1 1 0 1 1 1 0 Peptidase U49 PID PF00640.23 KFP13815.1 - 3.2e-08 33.7 0.1 5.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MACPF PF01823.19 KFP13816.1 - 1.6e-37 129.7 0.2 4.4e-37 128.2 0.2 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFP13816.1 - 2.9e-08 33.8 12.9 4.2e-08 33.3 11.0 2.5 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFP13816.1 - 1.5e-07 31.5 36.1 1.3e-05 25.3 10.6 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain MACPF PF01823.19 KFP13817.1 - 1.7e-42 145.9 0.1 5.5e-42 144.2 0.0 1.7 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFP13817.1 - 7e-11 42.2 10.2 7e-11 42.2 10.2 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFP13817.1 - 0.0017 18.5 10.8 0.0017 18.5 10.8 3.8 4 1 0 4 4 4 1 Thrombospondin type 1 domain DUF3655 PF12379.8 KFP13817.1 - 0.18 12.1 5.9 1.6 9.1 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) hSH3 PF14603.6 KFP13819.1 - 3.9e-16 59.3 0.2 1e-15 57.9 0.0 1.7 2 1 1 3 3 3 1 Helically-extended SH3 domain Pkinase PF00069.25 KFP13820.1 - 2.1e-67 227.3 0.0 3.2e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP13820.1 - 7.2e-37 127.1 0.0 1.3e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFP13820.1 - 2.4e-15 57.0 0.1 8.5e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFP13820.1 - 1.3e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP13820.1 - 0.00039 20.1 0.3 0.0017 18.0 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFP13820.1 - 0.0014 18.1 0.4 0.0026 17.2 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP13820.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP13820.1 - 0.032 13.2 0.1 0.032 13.2 0.1 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Peptidase_S8 PF00082.22 KFP13822.1 - 2.1e-23 83.1 1.7 4.7e-23 81.9 1.7 1.5 1 1 0 1 1 1 1 Subtilase family TMEM61 PF15105.6 KFP13823.1 - 5.3e-48 163.4 1.0 6.1e-48 163.2 1.0 1.0 1 0 0 1 1 1 1 TMEM61 protein family TMEM51 PF15345.6 KFP13823.1 - 0.17 11.7 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 CD20 PF04103.15 KFP13823.1 - 0.53 10.4 4.2 3 7.9 4.2 2.0 1 1 0 1 1 1 0 CD20-like family FAD_binding_4 PF01565.23 KFP13824.1 - 1.2e-16 60.7 0.1 2e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_2b PF00587.25 KFP13825.1 - 2e-34 119.1 0.0 3.8e-34 118.2 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFP13825.1 - 2.9e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain TPR_1 PF00515.28 KFP13826.1 - 3.6e-15 55.0 6.1 0.00023 20.8 0.9 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP13826.1 - 5e-12 45.0 5.2 0.0067 16.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP13826.1 - 3e-06 27.0 2.9 0.55 10.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP13826.1 - 0.00014 22.5 0.0 0.048 14.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP13826.1 - 0.00026 21.1 1.7 0.003 17.8 1.3 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP13826.1 - 0.0016 18.7 3.7 6.7 7.1 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP13826.1 - 0.0025 18.3 0.1 0.11 13.0 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP13826.1 - 0.0039 16.8 1.1 0.047 13.4 0.5 2.9 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 KFP13826.1 - 0.042 13.9 2.1 30 5.0 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP13826.1 - 0.077 13.9 0.1 20 6.3 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP13826.1 - 1.4 8.8 4.4 12 5.9 0.3 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat 4HBT PF03061.22 KFP13827.1 - 1.5e-21 76.5 0.1 1.5e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily START PF01852.19 KFP13827.1 - 2.3e-20 72.9 0.3 3.6e-14 52.7 0.0 2.3 1 1 1 2 2 2 2 START domain DUF716 PF04819.12 KFP13828.1 - 6e-29 100.4 7.7 1.1e-28 99.6 7.7 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) TnpB_IS66 PF05717.13 KFP13828.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein DUF1731 PF08338.11 KFP13830.1 - 8.9e-18 63.9 0.0 2.1e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KFP13830.1 - 4.3e-08 32.9 0.0 1.7e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFP13830.1 - 0.00091 19.2 0.3 0.0027 17.6 0.3 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFP13830.1 - 0.058 13.3 0.1 6.5 6.6 0.0 2.2 1 1 1 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 KFP13830.1 - 0.061 12.7 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFP13830.1 - 0.15 11.1 0.1 0.44 9.6 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain PIN_10 PF18478.1 KFP13830.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 PIN like domain rve PF00665.26 KFP13831.1 - 1.3e-21 77.0 0.1 2.5e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP13831.1 - 2e-13 50.1 2.6 2e-13 50.0 0.4 2.3 2 0 0 2 2 2 1 Integrase Zinc binding domain RNase_H PF00075.24 KFP13831.1 - 2.7e-05 24.4 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.18 KFP13832.1 - 3.1e-07 30.4 13.8 6.9e-07 29.3 13.8 1.6 1 0 0 1 1 1 1 MYND finger Ank_3 PF13606.6 KFP13832.1 - 5.7e-06 26.3 0.1 0.0064 16.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFP13832.1 - 0.0001 22.7 0.2 0.023 15.3 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP13832.1 - 0.00026 21.3 3.2 0.01 16.3 0.2 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KFP13832.1 - 0.00034 21.2 0.1 0.0013 19.3 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) MORN PF02493.20 KFP13833.1 - 2.1e-08 33.5 11.3 7.9e-05 22.3 1.8 3.5 3 0 0 3 3 3 3 MORN repeat RVT_1 PF00078.27 KFP13834.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S28 PF05577.12 KFP13835.1 - 3.2e-82 276.6 0.0 3.7e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KFP13835.1 - 1.1e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP13835.1 - 0.00012 22.7 1.4 0.0045 17.6 0.0 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP13835.1 - 0.00026 20.7 0.0 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 KFP13835.1 - 0.0037 16.0 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF2920 PF11144.8 KFP13835.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 KFP13835.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFP13835.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_47 PF01532.20 KFP13836.1 - 6.9e-170 565.9 0.0 8.1e-170 565.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UDPGP PF01704.18 KFP13837.1 - 3.1e-69 233.6 0.0 4.1e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFP13837.1 - 0.00053 20.4 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain GST_C_2 PF13410.6 KFP13838.1 - 1.1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP13838.1 - 0.0017 18.5 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC2_membrane_3 PF12698.7 KFP13839.1 - 7.6e-61 206.1 44.2 2e-43 148.9 13.8 3.5 4 0 0 4 4 4 2 ABC-2 family transporter protein ABC_tran PF00005.27 KFP13839.1 - 8.9e-58 194.7 0.0 1.6e-29 103.2 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KFP13839.1 - 6.3e-19 68.9 0.4 1.3e-06 28.5 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KFP13839.1 - 0.00036 21.2 0.6 0.77 10.5 0.2 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KFP13839.1 - 0.00059 19.6 0.0 1.2 8.7 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KFP13839.1 - 0.0016 19.0 0.9 0.47 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KFP13839.1 - 0.034 13.8 3.1 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KFP13839.1 - 0.15 12.4 0.0 27 5.1 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KFP13839.1 - 0.15 11.9 0.3 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase K_channel_TID PF07941.11 KFP13839.1 - 0.84 10.1 3.7 2.3 8.7 3.7 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_transf_10 PF00852.19 KFP13840.1 - 1.3e-57 194.4 0.7 1.7e-57 194.0 0.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFP13840.1 - 7.3e-32 110.1 0.0 1.4e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal mIF3 PF14877.6 KFP13840.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Pou PF00157.17 KFP13841.1 - 7.9e-37 125.1 1.4 1.4e-36 124.3 0.3 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP13841.1 - 2.7e-19 68.8 0.8 2.1e-18 65.9 0.4 2.3 2 0 0 2 2 2 1 Homeodomain DUF2497 PF10691.9 KFP13841.1 - 0.04 14.4 0.2 15 6.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Homeobox_KN PF05920.11 KFP13841.1 - 0.071 13.0 0.5 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain HTH_31 PF13560.6 KFP13841.1 - 0.14 12.5 0.2 5.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Lipocalin PF00061.23 KFP13842.1 - 0.0021 18.3 0.0 0.0023 18.2 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4926 PF16277.5 KFP13842.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4926) Lipocalin PF00061.23 KFP13843.1 - 3.1e-26 92.3 0.3 2.4e-14 53.8 0.0 2.0 1 1 1 2 2 2 2 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 KFP13843.1 - 0.00076 19.4 0.1 0.0013 18.6 0.1 1.5 1 1 0 1 1 1 1 Triabin Lipocalin_2 PF08212.12 KFP13843.1 - 0.021 14.7 0.2 0.81 9.6 0.0 2.1 1 1 1 2 2 2 0 Lipocalin-like domain VDE PF07137.11 KFP13843.1 - 0.073 12.6 0.1 8.2 5.9 0.1 2.0 1 1 0 2 2 2 0 VDE lipocalin domain Lipocalin PF00061.23 KFP13844.1 - 4.5e-18 65.9 0.0 5.2e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PepSY_2 PF13670.6 KFP13844.1 - 0.015 15.3 0.0 0.85 9.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain WD40 PF00400.32 KFP13845.1 - 3.1e-06 27.8 0.3 3.1e-06 27.8 0.3 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat HTH_3 PF01381.22 KFP13846.1 - 8.3e-13 48.2 0.2 1.2e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 KFP13846.1 - 1.7e-06 28.4 0.4 1.7e-06 28.4 0.4 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 KFP13846.1 - 0.00014 22.1 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KFP13846.1 - 0.021 14.8 0.2 0.029 14.4 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KFP13846.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-MYND PF01753.18 KFP13847.1 - 0.08 13.0 14.7 0.18 11.9 14.7 1.6 1 0 0 1 1 1 0 MYND finger Ras PF00071.22 KFP13848.1 - 8.3e-12 45.0 0.1 1.1e-05 25.1 0.3 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFP13848.1 - 4.1e-07 30.2 1.0 4.1e-07 30.2 1.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP13848.1 - 6.8e-06 25.6 0.1 2.2e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP13848.1 - 0.00014 21.9 0.0 0.00045 20.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFP13848.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Kunitz_BPTI PF00014.23 KFP13849.1 - 6.4e-36 122.4 18.7 5.6e-18 64.9 6.8 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.23 KFP13849.1 - 4e-26 91.9 0.0 5.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Megourin PF17560.2 KFP13849.1 - 0.58 10.4 9.1 1.1 9.6 2.8 2.5 2 0 0 2 2 2 0 Aphid Megourins Ank_2 PF12796.7 KFP13850.1 - 9e-16 58.2 0.0 9.7e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP13850.1 - 1.9e-14 53.5 0.1 2.8e-11 43.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP13850.1 - 7.4e-14 51.9 0.3 3.4e-13 49.8 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP13850.1 - 8.6e-11 41.1 0.0 3.5e-05 23.9 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFP13850.1 - 2.3e-09 37.3 0.1 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat DNA_pol_A_exo1 PF01612.20 KFP13851.1 - 3e-22 79.2 0.0 1.1e-21 77.3 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease Mut7-C PF01927.16 KFP13851.1 - 1.1e-13 51.5 0.2 3.2e-13 50.0 0.2 1.8 1 0 0 1 1 1 1 Mut7-C RNAse domain TPR_2 PF07719.17 KFP13852.1 - 1.1e-07 31.4 0.4 0.0049 16.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP13852.1 - 2.2e-06 27.2 0.1 0.00025 20.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP13852.1 - 0.00015 22.0 1.8 0.4 11.0 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP13852.1 - 0.0052 16.9 0.5 0.72 10.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP13852.1 - 0.016 15.0 0.6 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP13852.1 - 0.051 13.6 0.4 4.9 7.4 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP13852.1 - 0.15 12.8 0.4 4.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP13852.1 - 0.24 11.6 1.4 1.5 9.1 0.5 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GDA1_CD39 PF01150.17 KFP13853.1 - 4.6e-109 364.9 0.0 5.7e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.17 KFP13854.1 - 7.9e-86 288.4 0.0 3.6e-85 286.2 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FAM163 PF15069.6 KFP13854.1 - 0.13 12.7 1.5 0.25 11.8 1.5 1.4 1 0 0 1 1 1 0 FAM163 family Adeno_E3_CR2 PF02439.15 KFP13854.1 - 1.1 9.1 4.4 2.2 8.1 4.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GDA1_CD39 PF01150.17 KFP13855.1 - 3e-98 329.3 0.0 3.7e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family HA2 PF04408.23 KFP13855.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) Tmemb_185A PF10269.9 KFP13856.1 - 3.2e-06 27.0 12.1 7.5e-06 25.8 10.6 1.8 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein FAD_binding_1 PF00667.20 KFP13857.1 - 2.4e-48 164.6 0.0 3.8e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP13857.1 - 3.8e-31 108.2 0.0 5.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFP13857.1 - 1.1e-15 58.1 0.0 2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-RING_2 PF13639.6 KFP13858.1 - 1e-09 38.5 5.3 1.9e-09 37.7 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFP13858.1 - 2.2e-09 37.0 5.0 3.8e-09 36.3 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP13858.1 - 3e-09 36.7 5.2 4.6e-09 36.1 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP13858.1 - 1.5e-08 34.5 1.9 1.5e-08 34.5 1.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP13858.1 - 3.2e-08 33.3 7.3 8.1e-08 32.0 7.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP13858.1 - 6.2e-07 29.5 2.5 1.6e-06 28.2 2.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFP13858.1 - 2.8e-06 27.0 6.6 5.4e-06 26.1 6.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP13858.1 - 3.9e-06 26.6 8.2 0.00011 21.9 8.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP13858.1 - 0.00072 19.8 2.7 0.0014 18.9 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP13858.1 - 0.0019 18.2 1.9 0.0028 17.7 1.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFP13858.1 - 0.003 17.4 10.8 0.038 13.8 11.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP13858.1 - 0.022 14.5 0.5 0.022 14.5 0.5 2.4 3 0 0 3 3 3 0 RING-like zinc finger NMD3 PF04981.13 KFP13858.1 - 0.023 14.2 2.8 0.026 14.0 2.8 1.0 1 0 0 1 1 1 0 NMD3 family zf-P11 PF03854.14 KFP13858.1 - 0.028 14.1 10.0 0.13 11.9 3.8 2.8 1 1 1 2 2 2 0 P-11 zinc finger Gin PF10764.9 KFP13858.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.2 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_10 PF16685.5 KFP13858.1 - 0.21 11.7 6.6 0.5 10.6 6.6 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KFP13858.1 - 0.24 11.4 7.0 3 7.9 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF4428 PF14471.6 KFP13858.1 - 0.3 11.0 6.2 0.46 10.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Zn-C2H2_12 PF18112.1 KFP13858.1 - 0.3 11.6 3.7 3.4 8.2 0.3 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain YacG PF03884.14 KFP13858.1 - 0.59 9.9 7.1 2.9 7.7 1.0 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-WRNIP1_ubi PF18279.1 KFP13858.1 - 0.66 10.8 6.3 0.81 10.5 0.3 2.8 2 1 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Baculo_IE-1 PF05290.11 KFP13858.1 - 0.76 9.7 3.1 1 9.3 3.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_4 PF13894.6 KFP13858.1 - 3.5 8.7 7.5 4.2 8.5 0.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger DUF3090 PF11290.8 KFP13858.1 - 7.8 6.3 7.3 4.7 7.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) zf-Di19 PF05605.12 KFP13858.1 - 10 6.5 8.7 18 5.7 2.2 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 KFP13859.1 - 0.0025 17.7 13.8 0.0025 17.7 13.8 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP13859.1 - 0.0028 17.7 10.6 0.0028 17.7 10.6 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP13859.1 - 0.004 17.5 11.8 0.004 17.5 11.8 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KFP13859.1 - 0.012 15.5 13.8 0.012 15.5 13.8 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 GcpE PF04551.14 KFP13859.1 - 0.3 10.1 5.8 1.1 8.2 5.8 1.8 1 1 0 1 1 1 0 GcpE protein zf-C3HC4 PF00097.25 KFP13859.1 - 4.2 7.3 24.6 0.036 13.9 14.6 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 KFP13859.1 - 5.2 7.1 9.2 0.38 10.8 1.5 2.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.7 KFP13859.1 - 7.8 6.6 15.3 2.6 8.1 2.3 3.0 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-RING_UBOX PF13445.6 KFP13860.1 - 4.8e-08 32.9 5.0 4.8e-08 32.9 5.0 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP13860.1 - 2.8e-07 30.7 10.9 4.7e-07 30.0 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP13860.1 - 1.3e-05 25.1 10.0 2.4e-05 24.2 10.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP13860.1 - 0.00028 21.0 9.4 0.00028 21.0 9.4 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFP13860.1 - 0.00079 19.2 10.3 0.00079 19.2 10.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP13860.1 - 0.0013 18.5 11.7 0.003 17.4 11.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP13860.1 - 0.024 14.4 5.7 0.064 13.0 5.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KFP13860.1 - 0.028 14.3 8.1 0.078 12.8 8.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFP13860.1 - 0.22 11.3 10.4 0.76 9.6 10.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KFP13860.1 - 0.24 11.4 7.8 0.68 10.0 7.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 KFP13860.1 - 0.31 11.2 8.8 0.42 10.8 8.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger Lig_chan PF00060.26 KFP13861.1 - 1.2e-38 132.3 0.1 2e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFP13861.1 - 8.7e-33 113.9 0.0 8.4e-31 107.3 0.0 2.3 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFP13861.1 - 7e-32 110.0 0.1 3.8e-30 104.4 0.0 2.5 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP13861.1 - 2e-19 70.0 0.0 4.4e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CaM_bdg_C0 PF10562.9 KFP13861.1 - 9.6e-14 51.1 3.9 2.2e-13 50.0 3.9 1.7 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ion_trans_2 PF07885.16 KFP13861.1 - 0.023 14.7 0.6 0.063 13.2 0.6 1.7 1 0 0 1 1 1 0 Ion channel Peripla_BP_6 PF13458.6 KFP13861.1 - 0.03 14.0 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein Rieske PF00355.26 KFP13862.1 - 6.2e-15 54.9 0.2 1.2e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFP13862.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-C2H2_4 PF13894.6 KFP13863.1 - 1.3e-09 38.1 23.4 0.028 15.2 2.3 5.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP13863.1 - 1.1e-07 31.9 28.3 0.13 12.8 2.9 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.14 KFP13863.1 - 2.1e-05 24.2 0.2 6.1e-05 22.7 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_3rep PF18868.1 KFP13863.1 - 0.0012 19.5 2.0 0.3 11.8 0.0 3.2 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats DBD_Tnp_Hermes PF10683.9 KFP13863.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF4413 PF14372.6 KFP13863.1 - 0.097 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) zf_UBZ PF18439.1 KFP13863.1 - 0.14 11.8 14.1 0.52 9.9 1.3 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFP13863.1 - 0.52 10.4 23.5 3.1 7.9 3.8 4.9 5 0 0 5 5 5 0 BED zinc finger C1_2 PF03107.16 KFP13863.1 - 7.1 7.0 33.8 1 9.7 4.2 5.2 4 1 1 5 5 5 0 C1 domain RVT_1 PF00078.27 KFP13864.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KFP13867.1 - 6.2e-19 68.2 0.0 8.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 KFP13867.1 - 0.00099 18.7 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain CBFD_NFYB_HMF PF00808.23 KFP13868.1 - 2.8e-07 30.7 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SpoU_methylase PF00588.19 KFP13868.1 - 0.0068 16.6 0.0 0.0085 16.3 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Histone PF00125.24 KFP13868.1 - 0.017 15.5 5.9 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF4746 PF15928.5 KFP13868.1 - 0.061 12.7 8.0 0.062 12.7 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myc_N PF01056.18 KFP13868.1 - 0.077 12.9 6.4 0.073 13.0 6.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BUD22 PF09073.10 KFP13868.1 - 0.079 12.3 15.0 0.086 12.2 15.0 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 KFP13868.1 - 0.11 12.3 10.7 0.12 12.2 10.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KFP13868.1 - 0.22 10.8 11.3 0.22 10.8 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 KFP13868.1 - 0.31 10.4 16.1 0.36 10.2 16.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 KFP13868.1 - 0.35 11.3 12.3 0.49 10.9 12.3 1.3 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 KFP13868.1 - 0.63 8.3 9.8 0.59 8.4 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2956 PF11169.8 KFP13868.1 - 0.89 9.8 8.1 1.4 9.2 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF913 PF06025.12 KFP13868.1 - 1.1 8.2 4.1 0.97 8.3 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 KFP13868.1 - 1.3 6.9 4.2 1.2 7.0 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 KFP13868.1 - 1.3 9.3 14.1 1.5 9.1 14.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 KFP13868.1 - 1.3 8.9 11.9 1.4 8.8 11.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 KFP13868.1 - 1.4 7.6 5.8 1.4 7.6 5.8 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KFP13868.1 - 1.5 8.5 3.7 1.5 8.6 3.7 1.2 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 KFP13868.1 - 1.7 6.7 21.8 2 6.4 21.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 KFP13868.1 - 2.8 6.6 8.0 3.1 6.5 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Histone PF00125.24 KFP13869.1 - 0.039 14.3 4.7 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 BUD22 PF09073.10 KFP13869.1 - 0.043 13.2 14.9 0.044 13.1 14.9 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 KFP13869.1 - 0.16 11.8 11.9 0.16 11.8 11.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 KFP13869.1 - 0.18 11.2 16.1 0.19 11.1 16.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myc_N PF01056.18 KFP13869.1 - 0.28 11.1 8.5 0.27 11.1 8.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 KFP13869.1 - 0.31 10.3 12.4 0.29 10.4 12.4 1.1 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.10 KFP13869.1 - 0.44 10.8 13.6 0.45 10.8 13.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2956 PF11169.8 KFP13869.1 - 0.62 10.3 8.3 0.85 9.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Afi1 PF07792.12 KFP13869.1 - 0.88 10.1 9.5 0.86 10.1 9.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNA_pol_phi PF04931.13 KFP13869.1 - 0.91 7.5 21.8 1 7.4 21.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 KFP13869.1 - 1.4 7.7 7.7 1.3 7.7 7.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPN2_C PF18004.1 KFP13869.1 - 1.8 8.4 13.0 1.8 8.5 13.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 KFP13869.1 - 2 7.7 12.8 2.1 7.7 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 KFP13869.1 - 3.2 6.6 5.9 3 6.7 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 KFP13869.1 - 4.9 4.9 6.8 4.4 5.1 6.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 KFP13869.1 - 5.8 5.1 13.6 5.4 5.2 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFP13869.1 - 5.9 5.5 8.1 5.5 5.6 8.1 1.0 1 0 0 1 1 1 0 Presenilin ALAD PF00490.21 KFP13870.1 - 1.9e-116 388.7 0.0 2.3e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HAD_2 PF13419.6 KFP13871.1 - 2.1e-17 63.8 0.0 3.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP13871.1 - 1.1e-14 55.3 0.0 1.3e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFP13871.1 - 5.5e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like BCLP PF12304.8 KFP13871.1 - 0.19 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-casein like protein WD40 PF00400.32 KFP13872.1 - 2.6e-29 100.9 6.7 2.1e-05 25.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13872.1 - 2.4e-07 30.9 0.1 0.044 14.1 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP13872.1 - 0.00063 18.5 5.5 0.87 8.2 0.2 4.5 1 1 1 4 4 4 3 Nucleoporin Nup120/160 Retrotrans_gag PF03732.17 KFP13872.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Docking PF08990.11 KFP13872.1 - 1.9 8.2 3.9 0.48 10.1 0.7 1.6 2 0 0 2 2 2 0 Erythronolide synthase docking WD40 PF00400.32 KFP13873.1 - 9.2e-42 140.2 19.4 1.2e-08 35.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP13873.1 - 3.7e-15 56.0 0.1 0.0086 16.4 0.0 5.4 2 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KFP13873.1 - 3e-14 52.3 0.7 3e-14 52.3 0.7 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 KFP13873.1 - 0.00019 20.9 0.0 0.00078 18.9 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KFP13873.1 - 0.0003 19.9 0.3 2.7 6.9 0.0 4.0 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP13873.1 - 0.0076 14.9 0.8 2.3 6.8 0.0 3.8 1 1 1 4 4 4 1 Nucleoporin Nup120/160 DUF3776 PF12618.8 KFP13873.1 - 0.4 11.3 1.9 5.4 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) Ctr PF04145.15 KFP13874.1 - 9.3e-32 110.7 6.7 2.2e-31 109.5 6.7 1.6 1 1 0 1 1 1 1 Ctr copper transporter family FKBP_C PF00254.28 KFP13875.1 - 1.8e-24 85.8 0.0 4.5e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 KFP13875.1 - 0.0023 17.9 0.3 0.006 16.5 0.3 1.7 1 0 0 1 1 1 1 WH1 domain FPP PF05911.11 KFP13875.1 - 0.11 10.7 59.2 0.0022 16.3 51.6 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil GAS PF13851.6 KFP13875.1 - 0.3 10.4 75.8 0.036 13.4 35.1 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KFP13875.1 - 1 8.8 67.7 56 3.2 56.6 3.2 1 1 1 2 2 2 0 Intermediate filament protein Ribosomal_L11 PF00298.19 KFP13876.1 - 5.8e-18 65.2 0.2 8e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFP13876.1 - 1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain SHIPPO-rpt PF07004.12 KFP13877.1 - 0.002 18.9 0.2 0.004 18.0 0.2 1.6 1 0 0 1 1 1 1 Sperm-tail PG-rich repeat zf-MYND PF01753.18 KFP13879.1 - 2.6e-07 30.6 15.2 4.4e-07 29.9 15.2 1.5 1 0 0 1 1 1 1 MYND finger HNH_3 PF13392.6 KFP13879.1 - 3.1e-05 23.6 0.2 5.9e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.32 KFP13880.1 - 6.9e-06 26.7 8.0 0.12 13.3 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat MRP-L27 PF09809.9 KFP13881.1 - 1.1e-43 147.7 0.1 1.2e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 cNMP_binding PF00027.29 KFP13882.1 - 1.6e-51 172.3 0.2 4.7e-18 65.1 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFP13882.1 - 4.7e-25 89.0 0.2 8.2e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase FeoB_associated PF12669.7 KFP13882.1 - 0.11 12.9 1.8 0.28 11.6 1.8 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 KFP13882.1 - 0.16 12.9 0.1 0.37 11.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TNFR_16_TM PF18422.1 KFP13882.1 - 0.2 11.6 0.8 0.49 10.4 0.8 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF347 PF03988.12 KFP13882.1 - 0.33 11.2 4.6 8.1 6.7 2.7 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 KFP13882.1 - 4.9 6.6 10.5 13 5.3 10.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4347 PF14252.6 KFP13883.1 - 0.0003 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) IQ PF00612.27 KFP13883.1 - 0.015 15.0 10.3 0.086 12.7 0.2 3.5 4 0 0 4 4 4 0 IQ calmodulin-binding motif Phostensin PF13914.6 KFP13884.1 - 7.7e-44 149.7 8.8 2.2e-43 148.2 0.5 2.9 3 0 0 3 3 3 2 Phostensin PP1-binding and SH3-binding region DUF4770 PF15994.5 KFP13884.1 - 0.24 11.6 2.0 0.51 10.6 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM176 PF14851.6 KFP13884.1 - 0.27 10.9 3.5 1.3 8.7 0.8 2.2 2 0 0 2 2 2 0 FAM176 family Cullin PF00888.22 KFP13885.1 - 1.3e-30 106.7 2.1 1.3e-30 106.7 2.1 2.0 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 KFP13885.1 - 4.7e-24 84.7 1.2 2.6e-23 82.3 0.6 2.7 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cor1 PF04803.12 KFP13885.1 - 0.12 12.5 8.7 2.1 8.5 1.1 3.5 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Torsin PF06309.11 KFP13886.1 - 7.4e-14 51.9 0.0 2.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 KFP13886.1 - 0.00016 22.1 0.0 0.028 14.8 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFP13886.1 - 0.0013 19.0 0.2 0.37 11.1 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFP13886.1 - 0.0092 16.4 0.0 0.064 13.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP13886.1 - 0.01 16.4 0.0 0.035 14.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KFP13886.1 - 0.023 13.9 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 KFP13886.1 - 0.041 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein F5_F8_type_C PF00754.25 KFP13887.1 - 9e-14 51.7 0.1 1.1e-13 51.4 0.1 1.0 1 0 0 1 1 1 1 F5/8 type C domain Pkinase_Tyr PF07714.17 KFP13888.1 - 4.6e-84 281.7 0.0 6.3e-84 281.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP13888.1 - 1.5e-41 142.6 0.0 1.1e-40 139.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 KFP13888.1 - 0.0035 17.2 0.3 0.0061 16.5 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family F5_F8_type_C PF00754.25 KFP13888.1 - 0.0068 16.5 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 KFP13888.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF2062 PF09835.9 KFP13888.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Mid2 PF04478.12 KFP13888.1 - 0.058 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3377 PF11857.8 KFP13888.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Tubulin_C PF03953.17 KFP13889.1 - 1.5e-43 147.9 0.1 2.5e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFP13889.1 - 7.2e-42 143.8 0.0 1.3e-41 143.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFP13889.1 - 0.005 16.5 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFP13889.1 - 0.0098 15.1 0.1 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin like GDA1_CD39 PF01150.17 KFP13890.1 - 8.7e-37 126.8 0.0 1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family COBRA1 PF06209.13 KFP13891.1 - 1.1e-251 835.6 3.7 1.4e-251 835.3 3.7 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Nnf1 PF03980.14 KFP13891.1 - 0.6 10.5 2.7 0.4 11.1 0.3 1.9 2 0 0 2 2 2 0 Nnf1 Gln-synt_C PF00120.24 KFP13892.1 - 1e-15 57.6 0.0 1.3e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFP13892.1 - 1.8e-12 46.8 0.0 3.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Arrestin_C PF02752.22 KFP13893.1 - 6.2e-22 78.5 0.1 4.6e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFP13893.1 - 7.5e-14 52.0 0.1 4.8e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KFP13893.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like Ion_trans PF00520.31 KFP13894.1 - 7.3e-253 834.3 80.3 1.5e-67 227.4 2.3 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 KFP13894.1 - 1.9e-32 111.3 0.0 5.2e-32 109.9 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFP13894.1 - 1.1e-30 105.1 0.2 4.4e-30 103.2 0.3 2.0 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFP13894.1 - 3.7e-08 32.5 86.2 3.4e-06 26.0 10.4 9.5 6 4 2 9 9 9 4 Polycystin cation channel Tmemb_9 PF05434.11 KFP13894.1 - 0.24 11.3 1.5 10 6.0 0.0 3.2 2 0 0 2 2 2 0 TMEM9 Kelch_1 PF01344.25 KFP13895.1 - 3e-88 289.2 25.4 1.2e-16 60.0 1.7 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFP13895.1 - 6.8e-41 137.3 4.2 9.4e-08 32.1 0.0 6.3 4 2 2 6 6 6 6 Kelch motif BTB PF00651.31 KFP13895.1 - 8.6e-32 109.7 0.1 1.9e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFP13895.1 - 1.1e-31 107.6 9.8 1.8e-05 24.5 0.1 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP13895.1 - 1.7e-30 105.2 2.2 7.5e-30 103.1 2.2 2.2 1 1 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFP13895.1 - 2.6e-30 104.1 15.2 8.1e-06 26.0 0.2 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP13895.1 - 1.9e-21 75.8 7.1 0.00057 19.8 0.1 6.3 4 1 2 6 6 6 4 Galactose oxidase, central domain PQQ_3 PF13570.6 KFP13895.1 - 0.00053 20.4 11.5 0.46 11.0 0.0 5.1 5 0 0 5 5 5 2 PQQ-like domain Kelch_5 PF13854.6 KFP13895.1 - 0.00063 19.7 17.3 0.69 10.0 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Glu_cyclase_2 PF05096.12 KFP13895.1 - 0.14 11.6 0.1 6.5 6.1 0.0 2.7 1 1 2 3 3 3 0 Glutamine cyclotransferase FA_hydroxylase PF04116.13 KFP13897.1 - 1e-26 93.8 16.3 1e-26 93.8 16.3 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CLAMP PF14769.6 KFP13897.1 - 0.021 15.3 0.4 0.059 13.8 0.2 1.9 2 1 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF4886 PF16227.5 KFP13897.1 - 0.093 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) QueT PF06177.11 KFP13897.1 - 0.11 12.9 0.8 0.83 10.0 0.0 2.4 2 1 0 2 2 2 0 QueT transporter Peptidase_M14 PF00246.24 KFP13898.1 - 2.8e-61 207.9 0.0 3.4e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFP13898.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP13898.1 - 6.7e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFP13898.1 - 0.014 14.5 0.0 0.039 13.0 0.0 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF4713 PF15831.5 KFP13900.1 - 1 9.9 3.6 1.9 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) CUB PF00431.20 KFP13901.1 - 1.9e-188 614.0 6.6 1.5e-40 137.9 0.2 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFP13901.1 - 3.9e-73 245.1 0.1 9.8e-73 243.9 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFP13901.1 - 1.3e-19 70.2 28.4 1.2e-09 38.3 9.8 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP13901.1 - 2.8e-12 46.6 30.7 4.4e-07 30.0 8.5 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 KFP13901.1 - 1.1e-09 38.0 7.9 4.1e-05 23.4 2.3 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 KFP13901.1 - 3.6e-07 30.4 21.3 0.00065 20.0 6.7 2.9 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.7 KFP13901.1 - 3.4e-05 23.9 24.8 0.00042 20.4 4.8 3.6 2 1 1 3 3 3 2 EGF domain CUB_2 PF02408.20 KFP13901.1 - 8.2e-05 22.4 5.7 0.92 9.3 0.1 4.3 4 0 0 4 4 4 3 CUB-like domain hEGF PF12661.7 KFP13901.1 - 0.00028 21.4 19.9 0.068 13.8 5.5 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 KFP13901.1 - 0.0023 17.8 0.1 0.72 9.7 0.0 2.6 2 0 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 KFP13901.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AWS PF17907.1 KFP13901.1 - 3.4 7.8 10.2 9 6.4 1.2 3.0 2 0 0 2 2 2 0 AWS domain RVT_1 PF00078.27 KFP13902.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP13902.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KFP13903.1 - 0.00094 18.8 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP13907.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FXMRP1_C_core PF12235.8 KFP13908.1 - 2.7e-43 147.9 12.0 2.7e-43 147.9 12.0 2.7 1 1 1 2 2 2 1 Fragile X-related 1 protein core C terminal FXMR_C2 PF16098.5 KFP13908.1 - 1.9e-37 127.6 8.3 1.9e-37 127.6 8.3 2.2 3 0 0 3 3 3 1 Fragile X-related mental retardation protein C-terminal region 2 KH_9 PF17904.1 KFP13908.1 - 2e-37 127.4 1.2 5.7e-37 126.0 1.2 1.8 1 0 0 1 1 1 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 KFP13908.1 - 6.1e-19 67.7 2.3 6.1e-19 67.7 2.3 2.2 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_1 PF00013.29 KFP13908.1 - 1.9e-17 62.9 0.5 2.1e-09 37.0 0.7 2.5 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 KFP13908.1 - 1.6e-08 34.8 1.5 3.4e-06 27.4 0.5 2.9 3 0 0 3 3 3 1 Agenet domain KH_2 PF07650.17 KFP13908.1 - 0.00066 19.5 0.6 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFP13908.1 - 0.044 13.7 1.6 3 7.8 0.3 3.4 2 1 1 3 3 3 0 KH domain FXR_C3 PF16097.5 KFP13908.1 - 1.4 9.7 5.3 1.3 9.8 0.8 2.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 Sulfatase PF00884.23 KFP13909.1 - 6e-49 167.1 0.0 9.6e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP13909.1 - 3.8e-09 36.6 0.0 0.00033 20.4 0.0 2.2 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFP13909.1 - 0.002 16.8 0.0 0.013 14.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KFP13909.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Tmemb_185A PF10269.9 KFP13910.1 - 5e-61 206.5 28.0 6.6e-61 206.2 28.0 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein ASCH PF04266.14 KFP13911.1 - 0.018 15.6 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 ASCH domain Myotub-related PF06602.14 KFP13913.1 - 2.4e-150 500.4 0.0 3.2e-150 499.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP13913.1 - 1.1e-19 70.4 0.0 2.2e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 KFP13913.1 - 0.0004 20.2 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP13913.1 - 0.00063 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 KFP13913.1 - 0.0018 18.0 0.2 0.004 16.9 0.2 1.6 1 0 0 1 1 1 1 Myotubularin-associated protein Y_phosphatase3 PF13350.6 KFP13913.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 KFP13914.1 - 1.9e-149 497.4 0.0 2.3e-149 497.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP13914.1 - 5.5e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 KFP13914.1 - 0.00091 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP13914.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP13914.1 - 0.0015 18.5 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.8 KFP13914.1 - 0.0048 16.6 0.1 0.013 15.2 0.1 1.8 1 0 0 1 1 1 1 Myotubularin-associated protein DUF4441 PF14536.6 KFP13914.1 - 0.2 11.9 1.7 0.43 10.8 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Myb_CC_LHEQLE PF14379.6 KFP13914.1 - 0.83 9.4 3.7 24 4.7 1.0 2.5 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif CD99L2 PF12301.8 KFP13915.1 - 3.3e-47 160.9 1.0 3.5e-47 160.8 1.0 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 ACT_7 PF13840.6 KFP13915.1 - 0.026 14.3 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 ACT domain DUF2953 PF11167.8 KFP13915.1 - 0.087 12.9 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) HMG_box_2 PF09011.10 KFP13916.1 - 2.8e-49 165.6 10.3 5.5e-30 103.8 7.3 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KFP13916.1 - 8.8e-44 147.8 9.8 1e-27 96.3 0.1 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.6 KFP13916.1 - 0.00054 19.9 11.4 0.11 12.5 1.2 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Ribosomal_60s PF00428.19 KFP13916.1 - 0.026 15.1 18.0 0.082 13.5 18.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein YABBY PF04690.13 KFP13916.1 - 0.76 10.3 6.5 0.21 12.1 0.8 2.5 1 1 2 3 3 3 0 YABBY protein 7tm_1 PF00001.21 KFP13917.1 - 6.2e-41 140.5 27.4 7.8e-41 140.1 27.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP13917.1 - 1.3e-09 38.1 24.7 2.3e-09 37.3 24.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFP13917.1 - 0.44 10.3 21.9 0.56 10.0 14.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 RVT_1 PF00078.27 KFP13918.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP13919.1 - 0.006 16.1 0.0 0.015 14.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) VMA21 PF09446.10 KFP13920.1 - 4.5e-23 81.1 7.7 5e-23 81.0 7.7 1.0 1 0 0 1 1 1 1 VMA21-like domain RabGAP-TBC PF00566.18 KFP13921.1 - 2.8e-44 151.4 0.7 7.8e-44 149.9 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 KFP13921.1 - 1.9e-33 114.7 1.4 3.1e-19 68.9 0.2 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 KFP13921.1 - 0.03 13.9 0.6 0.15 11.7 0.1 2.6 2 0 0 2 2 2 0 EF hand zf-RING_2 PF13639.6 KFP13922.1 - 9.2e-12 45.1 7.8 1.6e-11 44.3 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP13922.1 - 1.4e-08 34.9 5.7 3.3e-08 33.7 5.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP13922.1 - 4.6e-08 32.7 3.7 9e-08 31.7 3.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP13922.1 - 4.8e-08 32.7 7.5 8.5e-08 31.9 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP13922.1 - 3.3e-07 30.1 7.9 5.8e-07 29.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KFP13922.1 - 1.9e-06 27.8 0.1 3.6e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KFP13922.1 - 2.4e-06 27.4 8.7 4.1e-06 26.6 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP13922.1 - 3.2e-05 23.8 5.0 6e-05 23.0 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP13922.1 - 0.00028 20.7 7.1 0.00045 20.0 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP13922.1 - 0.00043 20.1 9.0 0.0008 19.2 9.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP13922.1 - 0.0061 16.6 3.0 0.012 15.6 3.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KFP13922.1 - 0.014 15.6 1.7 0.034 14.4 1.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family DUF1251 PF06856.11 KFP13922.1 - 0.015 15.0 0.1 0.053 13.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1251) Zn_ribbon_17 PF17120.5 KFP13922.1 - 0.028 14.0 6.1 0.057 13.0 6.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KFP13922.1 - 0.037 14.1 3.3 0.085 12.9 2.6 2.0 2 0 0 2 2 2 0 Zinc-finger PHD PF00628.29 KFP13922.1 - 0.56 10.1 8.2 1 9.3 8.2 1.5 1 0 0 1 1 1 0 PHD-finger DUF5521 PF17659.1 KFP13923.1 - 1.9e-236 787.0 0.1 2.4e-236 786.6 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5521) DUF5088 PF17008.5 KFP13923.1 - 0.0038 17.0 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 KFP13923.1 - 0.028 14.4 0.0 0.16 12.0 0.0 2.3 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Eryth_link_C PF16915.5 KFP13923.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus Acyltransf_C PF16076.5 KFP13923.1 - 0.52 10.5 3.9 1 9.5 0.5 2.9 2 1 0 2 2 2 0 Acyltransferase C-terminus Pkinase PF00069.25 KFP13924.1 - 1.2e-54 185.5 0.0 2.1e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KFP13924.1 - 6.6e-54 183.4 0.0 1.2e-53 182.5 0.0 1.5 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KFP13924.1 - 6.2e-41 140.4 0.0 1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP13924.1 - 0.00097 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP13924.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family TIR PF01582.20 KFP13925.1 - 7.6e-31 107.3 0.1 2e-30 105.9 0.1 1.7 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.6 KFP13925.1 - 1.1e-21 77.0 0.0 3.2e-08 33.8 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP13925.1 - 1.9e-21 75.4 0.0 5.2e-15 54.7 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP13925.1 - 4.8e-21 74.6 0.1 1e-05 25.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP13925.1 - 1e-19 70.9 0.0 5.9e-06 26.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP13925.1 - 1e-17 64.0 0.1 3e-05 24.1 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP13925.1 - 9.8e-11 41.8 0.4 0.2 11.8 0.0 5.2 3 3 1 4 4 4 3 Immunoglobulin V-set domain TIR_2 PF13676.6 KFP13925.1 - 1.3e-06 29.0 0.0 2.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain Izumo-Ig PF16706.5 KFP13925.1 - 4.8e-05 23.3 0.2 0.15 12.1 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFP13925.1 - 0.0014 18.6 4.0 0.078 13.0 0.1 3.3 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFP13925.1 - 0.021 13.6 0.0 1.1 8.0 0.0 2.7 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E FAM199X PF15814.5 KFP13926.1 - 7.5e-205 679.2 22.4 8.4e-205 679.0 22.4 1.0 1 0 0 1 1 1 1 Protein family FAM199X Macoilin PF09726.9 KFP13926.1 - 0.07 11.7 12.1 0.084 11.4 12.1 1.1 1 0 0 1 1 1 0 Macoilin family COMM_domain PF07258.14 KFP13927.1 - 1.2e-17 63.8 0.3 5e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 COMM domain HOCHOB PF17943.1 KFP13927.1 - 0.071 13.8 0.0 0.72 10.6 0.0 2.1 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox Mito_carr PF00153.27 KFP13930.1 - 8.4e-50 166.7 0.2 2.6e-25 88.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 KFP13930.1 - 0.0016 17.6 0.3 0.0074 15.5 0.0 2.1 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Mito_carr PF00153.27 KFP13931.1 - 2.9e-56 187.4 2.6 2.6e-23 81.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFP13931.1 - 0.018 14.2 0.1 0.09 12.0 0.1 1.9 2 0 0 2 2 2 0 Fuseless GFA PF04828.14 KFP13932.1 - 0.17 12.2 0.2 3.6 8.0 0.0 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4410 PF14366.6 KFP13932.1 - 0.22 11.5 3.1 0.45 10.4 3.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) UQ_con PF00179.26 KFP13933.1 - 1.5e-40 138.1 0.1 1.6e-40 138.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP13933.1 - 0.00011 22.4 0.1 0.00014 22.2 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP13933.1 - 0.0081 15.9 0.0 0.0096 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP13933.1 - 0.0098 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 UEV domain DUF5487 PF17589.2 KFP13933.1 - 0.045 14.0 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5487) DUF2121 PF09894.9 KFP13933.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) R3H PF01424.22 KFP13934.1 - 9e-13 48.0 0.5 2.5e-12 46.6 0.5 1.8 1 0 0 1 1 1 1 R3H domain dsrm PF00035.26 KFP13934.1 - 2.5e-11 44.1 3.7 0.00014 22.5 0.1 4.1 4 0 0 4 4 4 2 Double-stranded RNA binding motif G-patch PF01585.23 KFP13934.1 - 6.1e-05 22.8 3.1 0.00054 19.8 0.8 3.2 2 1 0 2 2 2 1 G-patch domain S8_pro-domain PF16470.5 KFP13934.1 - 0.035 14.9 1.1 0.11 13.3 0.5 2.1 2 0 0 2 2 2 0 Peptidase S8 pro-domain G-patch_2 PF12656.7 KFP13934.1 - 0.047 13.8 0.1 0.21 11.7 0.1 2.1 1 0 0 1 1 1 0 G-patch domain Septin PF00735.18 KFP13935.1 - 9.6e-96 320.4 0.8 9.6e-96 320.4 0.8 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP13935.1 - 6.3e-05 23.0 1.1 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFP13935.1 - 0.0019 18.4 0.0 0.0054 16.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP13935.1 - 0.0021 18.5 0.3 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP13935.1 - 0.0022 18.3 1.1 0.0055 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFP13935.1 - 0.0028 17.2 3.2 1.2 8.7 0.0 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Atg14 PF10186.9 KFP13935.1 - 0.014 14.5 12.6 0.026 13.6 12.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_29 PF13555.6 KFP13935.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fzo_mitofusin PF04799.13 KFP13935.1 - 0.041 13.4 7.5 0.11 12.1 7.5 1.7 1 0 0 1 1 1 0 fzo-like conserved region AAA_7 PF12775.7 KFP13935.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IMD PF08397.11 KFP13935.1 - 0.059 12.7 13.7 0.12 11.8 13.7 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF1890 PF09001.11 KFP13935.1 - 0.1 13.0 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Glucan_synthase PF02364.15 KFP13935.1 - 0.13 10.4 0.0 0.13 10.4 0.0 1.8 2 0 0 2 2 2 0 1,3-beta-glucan synthase component FtsK_SpoIIIE PF01580.18 KFP13935.1 - 0.4 10.0 2.9 4 6.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KFP13935.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.0 3 1 1 4 4 4 0 RsgA GTPase DUF87 PF01935.17 KFP13935.1 - 0.74 9.9 7.6 3 7.9 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 KFP13935.1 - 0.84 9.1 10.0 1.2 8.6 10.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 KFP13935.1 - 3.1 7.8 6.7 25 4.9 0.1 2.6 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 KFP13935.1 - 3.3 8.2 6.2 0.46 11.0 0.2 2.4 2 2 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KFP13935.1 - 6.7 7.2 25.8 4.2e+03 -2.0 25.8 2.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP13935.1 - 8.5 6.1 10.1 14 5.3 10.1 1.3 1 0 0 1 1 1 0 AAA domain Nkap_C PF06047.11 KFP13936.1 - 5.1e-50 167.8 2.0 5.1e-50 167.8 2.0 2.9 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain NKAP PF15692.5 KFP13936.1 - 5.8e-12 46.2 20.4 5.8e-12 46.2 20.4 4.0 2 1 2 4 4 4 1 NF-kappa-B-activating protein SOBP PF15279.6 KFP13936.1 - 0.22 12.1 16.2 0.39 11.3 16.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 KFP13936.1 - 0.58 8.8 12.1 0.65 8.6 12.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BTB PF00651.31 KFP13937.1 - 1.1e-19 70.7 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP13937.1 - 4.1e-06 27.0 10.8 0.00021 21.6 1.9 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP13937.1 - 0.00011 22.7 15.7 0.029 15.2 2.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP13937.1 - 0.021 15.3 16.7 0.44 11.1 1.5 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFP13937.1 - 0.037 14.7 4.8 0.31 11.7 0.3 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KFP13937.1 - 0.072 13.1 12.8 2.7 8.1 0.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger HNH PF01844.23 KFP13937.1 - 0.09 13.0 2.7 6.3 7.1 0.5 2.7 2 0 0 2 2 2 0 HNH endonuclease zf-C2H2_11 PF16622.5 KFP13937.1 - 0.29 10.9 9.5 0.48 10.2 3.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 KFP13937.1 - 0.74 9.8 4.0 1.7 8.7 4.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.7 KFP13937.1 - 4.3 7.7 6.7 13 6.2 0.3 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Na_K-ATPase PF00287.18 KFP13938.1 - 4.3e-93 311.6 0.4 4.9e-93 311.4 0.4 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Lamp PF01299.17 KFP13939.1 - 1.1e-52 177.8 12.7 4.9e-46 156.3 2.2 2.4 2 1 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFP13939.1 - 4.1e-05 23.4 1.0 0.00011 22.0 0.5 1.9 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Cullin PF00888.22 KFP13940.1 - 5.8e-212 705.6 18.5 9.3e-212 705.0 18.5 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP13940.1 - 1.3e-25 89.2 1.6 5.6e-25 87.2 1.6 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KFP13940.1 - 4.2e-05 23.7 0.3 4.2e-05 23.7 0.3 3.2 3 1 0 3 3 3 1 SecA Wing and Scaffold domain PG_binding_4 PF12229.8 KFP13940.1 - 0.35 11.2 2.5 2 8.7 0.1 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Pre-PUA PF17832.1 KFP13941.1 - 1.2e-25 90.0 0.1 1.8e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFP13941.1 - 3.7e-21 74.9 0.1 6.3e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 PUA domain Methyltr_RsmF_N PF17125.5 KFP13941.1 - 0.055 14.0 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF1947 PF09183.10 KFP13941.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) ANF_receptor PF01094.28 KFP13943.1 - 3.5e-61 207.3 1.0 5e-61 206.8 1.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP13943.1 - 5.5e-59 198.3 0.0 1e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP13943.1 - 1.1e-45 154.5 0.0 2.3e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP13943.1 - 2.3e-24 86.1 0.0 4.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2061 PF09834.9 KFP13943.1 - 0.082 13.4 0.2 0.27 11.8 0.2 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) NusG_add PF18298.1 KFP13943.1 - 0.089 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 NusG additional domain Tho2 PF11262.8 KFP13944.1 - 3.7e-104 348.1 2.3 3.7e-104 348.1 2.3 4.5 4 2 1 5 5 5 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 KFP13944.1 - 6.6e-83 279.4 6.2 4.7e-57 194.0 2.9 4.8 3 2 1 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 KFP13944.1 - 3.6e-37 126.3 1.0 3.1e-36 123.3 0.2 2.8 3 0 0 3 3 3 1 Transcription- and export-related complex subunit STAG PF08514.11 KFP13945.1 - 6.2e-39 132.4 0.1 7.1e-39 132.2 0.1 1.0 1 0 0 1 1 1 1 STAG domain Ribosomal_S18 PF01084.20 KFP13946.1 - 1.1e-15 57.5 0.0 2.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Radial_spoke PF04712.12 KFP13947.1 - 6e-13 48.6 0.0 7.5e-05 21.9 0.0 3.2 3 1 0 3 3 3 3 Radial spokehead-like protein EHN PF06441.12 KFP13948.1 - 2e-35 121.4 0.2 3.6e-35 120.6 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFP13948.1 - 2e-23 83.4 0.0 2.5e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP13948.1 - 0.00026 21.6 0.0 0.00076 20.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family p31comet PF06581.12 KFP13949.1 - 7.9e-73 244.9 0.0 9e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding zf_UBZ PF18439.1 KFP13950.1 - 3.9e-12 45.6 2.1 3.9e-12 45.6 2.1 2.0 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KFP13950.1 - 2.5e-09 37.9 0.0 4.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 KFP13950.1 - 3.6e-08 33.6 0.0 2.4e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family Ribosomal_60s PF00428.19 KFP13950.1 - 4.2 8.0 8.9 2.6 8.7 0.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Xpo1 PF08389.12 KFP13951.1 - 9.6e-34 116.6 2.9 2.6e-33 115.2 2.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KFP13951.1 - 3e-05 23.8 0.0 0.00012 21.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain RNA_pol_A_bac PF01000.26 KFP13952.1 - 3.5e-30 104.6 0.0 5.5e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFP13952.1 - 1.4e-19 69.3 0.0 1.8e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain INCENP_N PF12178.8 KFP13952.1 - 0.09 12.8 0.7 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Yip1 PF04893.17 KFP13953.1 - 1.7e-05 24.6 18.9 3e-05 23.8 18.8 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.9 KFP13953.1 - 0.014 15.8 2.4 0.033 14.5 1.9 2.0 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 LRR_6 PF13516.6 KFP13954.1 - 1.7e-10 40.1 4.5 0.11 12.5 0.2 5.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 KFP13954.1 - 5.9e-06 26.1 1.2 3.6 8.5 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 KFP13954.1 - 0.00017 21.9 3.5 6.9 7.2 1.2 4.1 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP13954.1 - 0.25 11.1 6.9 11 5.8 0.4 4.1 3 2 0 3 3 3 0 Leucine rich repeat Pilt PF15453.6 KFP13955.1 - 3e-147 490.8 25.3 7e-116 387.6 17.1 2.5 1 1 1 2 2 2 2 Protein incorporated later into Tight Junctions Spc7 PF08317.11 KFP13955.1 - 0.0074 15.2 13.0 0.011 14.6 11.6 1.9 1 1 1 2 2 2 1 Spc7 kinetochore protein HMMR_N PF15905.5 KFP13955.1 - 0.035 13.6 14.3 0.054 13.0 14.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 KFP13955.1 - 0.25 11.0 17.7 1.8 8.2 17.7 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KFP13955.1 - 0.66 10.2 6.9 1.1 9.5 5.9 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 KFP13955.1 - 0.67 10.3 7.3 0.18 12.1 2.9 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Syntaxin_2 PF14523.6 KFP13955.1 - 1.4 9.4 5.0 0.81 10.1 2.4 2.0 3 0 0 3 3 1 0 Syntaxin-like protein DUF4407 PF14362.6 KFP13955.1 - 1.5 8.1 5.0 1.3 8.3 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KFP13955.1 - 1.6 9.1 11.7 1.1 9.6 9.8 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 KFP13955.1 - 1.6 6.5 5.6 2.3 6.0 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.11 KFP13955.1 - 3 8.5 10.9 0.64 10.6 2.5 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 KFP13955.1 - 3.5 7.1 7.1 5.8 6.4 7.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 KFP13955.1 - 3.6 8.2 15.4 0.37 11.4 10.2 2.1 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin_1 PF12718.7 KFP13955.1 - 4.8 7.3 20.5 8.3 6.6 10.6 2.3 1 1 1 2 2 2 0 Tropomyosin like ATG16 PF08614.11 KFP13955.1 - 6.4 7.0 19.6 0.16 12.2 12.5 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4795 PF16043.5 KFP13955.1 - 8.2 6.0 12.6 6.2 6.4 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ADIP PF11559.8 KFP13955.1 - 9 6.4 17.7 38 4.3 6.1 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Wtap PF17098.5 KFP13955.1 - 9.5 6.1 13.6 8.7 6.3 10.0 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family TMPIT PF07851.13 KFP13955.1 - 9.9 5.3 7.1 2 7.6 2.9 1.7 1 1 0 1 1 1 0 TMPIT-like protein zf-C2H2_jaz PF12171.8 KFP13956.1 - 0.00019 21.6 1.9 0.00019 21.6 1.9 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP13956.1 - 0.019 15.3 2.8 2.1 8.7 0.4 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP13956.1 - 8.6 6.9 15.1 0.43 11.0 1.9 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2465 PF10239.9 KFP13958.1 - 4.2e-131 437.0 0.0 5.5e-131 436.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.19 KFP13959.1 - 3.4e-44 151.1 0.4 5.6e-44 150.4 0.4 1.4 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.22 KFP13959.1 - 2.4e-13 49.7 9.3 5.4e-13 48.6 9.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 KFP13959.1 - 1.2e-09 37.0 5.5 0.00017 20.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP13959.1 - 2.9e-09 36.1 1.4 0.0002 21.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP13959.1 - 5.1e-09 35.2 0.4 0.0048 16.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP13959.1 - 5.3e-09 36.4 3.3 0.00064 20.1 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP13959.1 - 2.8e-05 23.9 1.2 0.086 12.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair RasGEF_N PF00618.20 KFP13959.1 - 0.00015 21.9 0.9 0.018 15.3 0.0 3.3 3 1 0 3 3 3 1 RasGEF N-terminal motif EGF_CA PF07645.15 KFP13960.1 - 1.5e-92 303.5 268.4 2.6e-09 37.1 6.1 18.7 19 2 0 19 19 19 15 Calcium-binding EGF domain TB PF00683.17 KFP13960.1 - 3e-54 180.5 60.7 1.4e-16 60.0 9.9 6.3 5 0 0 5 5 5 4 TB domain cEGF PF12662.7 KFP13960.1 - 1.5e-46 155.9 167.6 2.1e-07 30.7 2.6 18.5 18 1 0 18 18 18 12 Complement Clr-like EGF-like EGF PF00008.27 KFP13960.1 - 4e-34 116.5 256.9 0.00034 20.9 7.1 19.9 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.7 KFP13960.1 - 3.6e-15 55.9 229.9 0.00016 22.1 1.9 20.6 20 1 0 20 20 20 13 Human growth factor-like EGF EGF_3 PF12947.7 KFP13960.1 - 1e-14 54.4 201.1 0.0024 18.0 8.8 19.4 17 1 1 18 18 18 13 EGF domain Plasmod_Pvs28 PF06247.11 KFP13960.1 - 0.00029 21.1 13.1 0.0014 18.9 3.0 17.2 18 1 0 18 18 18 9 Pvs28 EGF domain FXa_inhibition PF14670.6 KFP13960.1 - 0.00049 20.3 24.1 0.00064 19.9 7.3 20.0 19 2 2 21 21 21 13 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 KFP13960.1 - 0.00074 19.5 1.8 0.00074 19.5 1.8 18.8 22 0 0 22 22 22 7 MSP1 EGF domain 1 TPR_2 PF07719.17 KFP13961.1 - 2.6e-16 58.3 19.3 0.00084 19.3 0.0 8.9 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP13961.1 - 7.8e-15 54.0 13.6 0.0031 17.2 0.0 7.8 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP13961.1 - 1.8e-12 46.4 12.3 0.00063 19.8 0.0 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP13961.1 - 1.1e-11 44.7 0.6 4.7e-07 29.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP13961.1 - 2e-11 43.7 8.5 0.17 12.8 0.0 8.1 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP13961.1 - 2.6e-09 36.6 0.0 0.00021 20.9 0.2 5.3 4 1 1 5 5 5 1 TPR repeat TPR_19 PF14559.6 KFP13961.1 - 9.5e-09 35.6 5.2 0.00098 19.6 0.0 7.1 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP13961.1 - 1.9e-08 34.1 3.2 8.4e-05 22.7 0.0 5.6 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP13961.1 - 2.9e-07 31.0 1.9 0.00053 20.6 0.1 4.7 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP13961.1 - 1.8e-05 24.9 16.3 0.0072 16.5 0.2 5.7 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP13961.1 - 1.9e-05 24.9 17.1 0.31 11.4 0.6 7.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP13961.1 - 0.0001 22.1 6.2 8.8 6.6 0.3 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP13961.1 - 0.0034 17.9 9.9 0.88 10.3 0.0 7.0 9 0 0 9 9 8 1 Tetratricopeptide repeat ChAPs PF09295.10 KFP13961.1 - 0.0051 15.9 0.0 1 8.3 0.1 2.6 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 KFP13961.1 - 0.0095 16.4 5.2 0.04 14.4 0.5 3.5 2 2 0 2 2 2 1 Bacterial transcriptional activator domain DSHCT PF08148.12 KFP13961.1 - 0.044 13.4 0.1 0.16 11.6 0.1 1.9 1 0 0 1 1 1 0 DSHCT (NUC185) domain RPN7 PF10602.9 KFP13961.1 - 0.047 13.4 2.7 1.4 8.6 0.0 4.0 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_15 PF13429.6 KFP13961.1 - 0.22 10.7 7.7 0.44 9.7 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP13961.1 - 0.96 9.4 13.0 9.7 6.2 0.2 6.7 7 1 1 8 8 7 0 Tetratricopeptide repeat BIRC6 PF12356.8 KFP13962.1 - 1.5e-67 226.4 3.9 1.5e-67 226.4 3.9 2.4 3 0 0 3 3 3 1 Baculoviral IAP repeat-containing protein 6 UQ_con PF00179.26 KFP13962.1 - 1.6e-29 102.4 0.0 3.5e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.21 KFP13962.1 - 1.1e-20 74.0 3.0 2.8e-20 72.7 3.0 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.13 KFP13962.1 - 0.00038 20.3 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 UEV domain Yip1 PF04893.17 KFP13963.1 - 2.9e-10 40.1 21.4 6.9e-10 38.9 21.1 1.8 1 1 0 1 1 1 1 Yip1 domain UPF0139 PF03669.13 KFP13963.1 - 0.065 13.1 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) CARD PF00619.21 KFP13964.1 - 9.9e-17 60.8 0.1 2.4e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 Caspase recruitment domain LRR_4 PF12799.7 KFP13964.1 - 7.9e-07 29.3 13.0 0.031 14.7 0.1 4.8 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP13964.1 - 3.8e-06 26.6 8.0 0.018 14.8 0.1 4.5 3 2 2 5 5 5 2 Leucine rich repeat HTH_34 PF13601.6 KFP13964.1 - 0.034 14.3 0.2 0.2 11.9 0.0 2.4 3 0 0 3 3 3 0 Winged helix DNA-binding domain LRR_6 PF13516.6 KFP13964.1 - 0.037 14.1 8.7 0.077 13.1 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KFP13964.1 - 0.059 13.9 6.7 4.8 8.1 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat BORG_CEP PF14957.6 KFP13966.1 - 2.2e-33 116.1 2.2 3.1e-33 115.6 2.2 1.2 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.28 KFP13966.1 - 4e-09 36.7 0.0 1.2e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain S6OS1 PF15676.5 KFP13966.1 - 0.017 13.6 0.2 0.025 13.1 0.2 1.2 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family TPR_1 PF00515.28 KFP13967.1 - 6e-05 22.7 8.8 0.014 15.2 2.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP13967.1 - 0.00044 20.2 3.3 0.04 14.1 1.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP13967.1 - 0.0067 16.1 0.3 0.8 9.4 0.0 2.6 2 0 0 2 2 2 1 TPR repeat Sec16_C PF12931.7 KFP13967.1 - 0.013 15.1 0.4 0.022 14.4 0.4 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_2 PF07719.17 KFP13967.1 - 0.027 14.6 13.6 0.035 14.2 1.2 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP13967.1 - 0.027 15.0 0.9 0.11 13.0 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP13967.1 - 0.03 14.7 1.9 3.1 8.4 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CCDC106 PF15794.5 KFP13967.1 - 0.044 13.5 2.0 0.076 12.7 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SKA1 PF07160.12 KFP13967.1 - 0.056 13.3 1.1 0.091 12.6 1.1 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 KFP13967.1 - 0.078 12.3 1.2 0.13 11.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_Ag35 PF03286.14 KFP13967.1 - 0.3 10.9 3.1 0.48 10.2 3.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein POX PF07526.11 KFP13967.1 - 0.4 11.2 4.0 0.85 10.2 4.0 1.6 1 1 0 1 1 1 0 Associated with HOX HAD_2 PF13419.6 KFP13968.1 - 1.5e-23 83.8 0.0 2.1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP13968.1 - 2.8e-13 50.6 0.0 3.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFP13968.1 - 4.7e-12 45.8 0.0 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Pkinase PF00069.25 KFP13970.1 - 2e-52 178.2 0.0 3.2e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP13970.1 - 1.1e-30 106.8 0.0 1.9e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.26 KFP13970.1 - 1.5e-17 64.0 0.2 1.9e-16 60.5 0.1 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif Kinase-like PF14531.6 KFP13970.1 - 4e-05 23.1 0.0 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP13970.1 - 0.0025 17.2 0.1 0.0048 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFP13970.1 - 0.019 14.6 1.0 4.5 6.8 0.1 2.8 1 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP13970.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4187 PF13821.6 KFP13971.1 - 4.4e-21 74.4 1.5 4.4e-21 74.4 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFP13971.1 - 1.4e-14 53.7 1.1 2.6e-14 52.8 1.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP13971.1 - 2.2e-06 27.7 0.5 2.2e-06 27.7 0.5 2.7 2 0 0 2 2 2 1 G-patch domain ALMT PF11744.8 KFP13971.1 - 9 5.0 6.7 2.1 7.1 1.4 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter WD40 PF00400.32 KFP13972.1 - 6.8e-36 121.7 10.0 3e-08 34.2 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.12 KFP13972.1 - 5.3e-27 95.3 3.6 5.3e-27 95.3 3.6 3.0 2 2 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 KFP13972.1 - 7.4e-09 35.8 0.2 0.023 15.0 0.0 5.7 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP13972.1 - 0.0057 15.4 0.0 5.4 5.6 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KFP13972.1 - 0.019 13.7 0.0 3.4 6.2 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 7tm_1 PF00001.21 KFP13973.1 - 1.7e-28 99.6 12.2 2e-28 99.5 12.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP13973.1 - 0.0051 16.6 4.8 0.0065 16.2 4.8 1.3 1 1 0 1 1 1 1 Olfactory receptor Ctr PF04145.15 KFP13974.1 - 2e-14 54.5 4.8 2e-14 54.4 4.8 1.2 1 1 0 1 1 1 1 Ctr copper transporter family PH PF00169.29 KFP13975.1 - 9.6e-06 26.1 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Flp_C PF05202.12 KFP13975.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Recombinase Flp protein Sec1 PF00995.23 KFP13976.1 - 5.1e-96 323.2 2.9 6.1e-96 322.9 2.9 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.6 KFP13976.1 - 0.029 14.6 0.8 0.072 13.4 0.8 1.6 1 0 0 1 1 1 0 Putative coat protein DUF365 PF04033.12 KFP13976.1 - 0.12 12.6 0.2 1.7 9.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF365) Sec1 PF00995.23 KFP13977.1 - 1.1e-15 57.9 0.0 1.2e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PDZ PF00595.24 KFP13978.1 - 3.1e-24 85.1 0.7 6.9e-15 55.2 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP13978.1 - 3.9e-16 58.6 0.6 6e-08 32.4 0.0 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP13978.1 - 2.1e-08 34.4 0.1 0.00017 21.9 0.0 2.8 2 1 0 2 2 2 2 PDZ domain RVT_1 PF00078.27 KFP13979.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-ATPase_G PF03179.15 KFP13981.1 - 3.6e-25 88.5 8.0 4.1e-25 88.3 8.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3924 PF13062.6 KFP13981.1 - 0.067 13.2 0.2 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) OmpH PF03938.14 KFP13981.1 - 0.14 12.5 6.5 0.17 12.2 6.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.19 KFP13981.1 - 0.3 11.0 4.9 0.4 10.6 4.9 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF4481 PF14800.6 KFP13982.1 - 1.4e-49 169.2 5.3 1.5e-49 169.0 5.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) DUF2070 PF09843.9 KFP13982.1 - 0.028 12.7 0.7 0.026 12.8 0.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CDP-OH_P_transf PF01066.21 KFP13982.1 - 0.04 14.7 0.2 0.08 13.7 0.2 1.4 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase TNF PF00229.18 KFP13984.1 - 4.9e-36 123.5 0.1 7.3e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF4457 PF14652.6 KFP13984.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) TNF PF00229.18 KFP13986.1 - 1.7e-13 50.6 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family RVT_1 PF00078.27 KFP13987.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arm PF00514.23 KFP13988.1 - 9.6e-49 162.0 8.5 2.4e-09 36.9 0.1 8.8 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP13988.1 - 2.6e-08 34.1 0.9 0.0061 16.9 0.0 3.3 2 2 1 3 3 3 3 HEAT repeats HEAT PF02985.22 KFP13988.1 - 9.2e-05 22.4 4.8 0.33 11.3 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 KFP13988.1 - 0.0052 15.4 0.0 0.38 9.3 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 KFP13988.1 - 0.0093 16.0 0.8 0.52 10.4 0.0 3.4 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 KFP13988.1 - 0.011 16.2 4.1 28 5.3 0.1 5.0 4 1 1 5 5 5 0 HEAT-like repeat RasGEF_N PF00618.20 KFP14004.1 - 3.4e-13 49.8 0.2 8.9e-12 45.2 0.2 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFP14004.1 - 3.6e-11 43.5 0.0 1.1e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KFP14004.1 - 1.3e-10 41.5 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP14004.1 - 5.6e-10 38.9 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain cNMP_binding PF00027.29 KFP14004.1 - 2e-07 31.0 0.0 0.00015 21.8 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 KFP14004.1 - 8.8e-05 22.8 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain FNIP_M PF14637.6 KFP14005.1 - 2.4e-91 305.8 0.8 4.4e-91 304.9 0.5 1.6 2 0 0 2 2 2 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 KFP14005.1 - 7.1e-73 244.3 0.4 3e-72 242.3 0.4 2.1 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 KFP14005.1 - 1.1e-27 97.9 2.0 1.1e-27 97.9 2.0 4.2 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus Pro_isomerase PF00160.21 KFP14006.1 - 2.7e-46 157.7 0.5 3e-46 157.6 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ETF_QO PF05187.13 KFP14007.1 - 9.5e-49 163.9 0.0 1.6e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KFP14007.1 - 2.5e-09 37.2 1.4 3.5e-05 23.5 0.7 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFP14007.1 - 2e-08 33.7 0.9 2.8e-05 23.4 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFP14007.1 - 3.6e-08 32.9 0.0 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KFP14007.1 - 1.8e-06 28.1 0.1 9.8e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFP14007.1 - 2e-06 27.3 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFP14007.1 - 7e-05 22.0 0.2 9.7e-05 21.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KFP14007.1 - 0.00016 20.5 0.5 0.00024 19.9 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFP14007.1 - 0.00023 21.6 0.0 0.34 11.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFP14007.1 - 0.00024 21.1 0.0 0.0008 19.4 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KFP14007.1 - 0.00024 20.4 0.2 0.00057 19.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KFP14007.1 - 0.0036 16.7 0.2 0.0055 16.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFP14007.1 - 0.0047 15.8 0.0 0.057 12.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KFP14007.1 - 0.0072 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFP14007.1 - 0.017 14.2 0.3 0.028 13.5 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KFP14007.1 - 0.031 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KFP14007.1 - 0.034 13.4 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_7 PF12838.7 KFP14007.1 - 0.085 13.5 0.9 0.29 11.8 0.5 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain LRR_8 PF13855.6 KFP14008.1 - 8.6e-45 150.3 30.6 4.7e-14 51.9 4.9 5.5 2 2 3 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.21 KFP14008.1 - 3.8e-26 92.0 17.7 5.6e-26 91.4 17.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_5 PF13306.6 KFP14008.1 - 2.3e-19 69.6 5.2 3e-09 36.9 1.0 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP14008.1 - 6.2e-19 67.8 31.1 1e-06 28.9 3.3 6.7 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP14008.1 - 1.1e-10 41.3 17.9 0.0026 17.3 0.6 4.2 1 1 3 4 4 4 4 Leucine-rich repeat Ldl_recept_a PF00057.18 KFP14008.1 - 6.4e-07 29.5 5.1 6.4e-07 29.5 5.1 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRRNT PF01462.18 KFP14008.1 - 7.9e-05 22.2 0.2 0.00019 21.0 0.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP14008.1 - 0.0066 16.8 25.9 2 9.3 0.1 9.1 9 1 1 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP14008.1 - 0.25 11.5 13.3 25 5.3 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich repeat TMEM144 PF07857.12 KFP14009.1 - 2.1e-131 437.9 15.6 2.3e-131 437.7 15.6 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 KFP14009.1 - 1.1e-11 44.6 12.6 2.6e-10 40.1 3.1 2.4 2 0 0 2 2 2 2 Sugar transport protein FAM198 PF15051.6 KFP14010.1 - 2.2e-146 486.8 0.9 2.6e-146 486.6 0.9 1.1 1 0 0 1 1 1 1 FAM198 protein Lig_chan PF00060.26 KFP14011.1 - 3.6e-59 198.9 0.1 5.7e-59 198.2 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KFP14011.1 - 2.3e-58 198.0 0.0 4.1e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KFP14011.1 - 6e-46 155.4 0.1 1.2e-45 154.4 0.1 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP14011.1 - 1.1e-24 87.1 0.0 2.1e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP14011.1 - 3.4e-06 26.9 0.0 4.4e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 Periplasmic binding protein Neur_chan_LBD PF02931.23 KFP14013.1 - 4.5e-53 179.9 0.2 5.7e-53 179.5 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP14013.1 - 6.1e-35 121.4 0.1 1.2e-34 120.5 0.1 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3267 PF11667.8 KFP14013.1 - 0.0091 16.3 1.8 0.12 12.7 1.8 2.3 1 1 0 1 1 1 1 Putative zincin peptidase CUB PF00431.20 KFP14015.1 - 1e-17 64.5 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.17 KFP14015.1 - 2.9e-13 49.9 12.0 4.6e-13 49.3 12.0 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain Peptidase_C1 PF00112.23 KFP14017.1 - 3.8e-58 197.1 4.4 4.5e-58 196.9 4.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFP14017.1 - 2.1e-07 30.1 0.1 0.00074 18.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 KFP14017.1 - 0.098 13.1 0.7 0.17 12.3 0.1 1.7 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Trp_dioxygenase PF03301.13 KFP14018.1 - 1.3e-164 547.6 5.0 1.5e-164 547.4 5.0 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase ASC PF00858.24 KFP14019.1 - 4.8e-99 332.3 7.4 5.8e-99 332.0 7.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF2189 PF09955.9 KFP14019.1 - 0.78 10.0 3.2 78 3.5 0.0 2.5 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) Guanylate_cyc PF00211.20 KFP14020.1 - 1.4e-65 220.4 0.0 2e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP14020.1 - 2.8e-57 193.7 0.0 6.3e-57 192.5 0.0 1.6 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFP14020.1 - 7e-46 156.2 0.0 1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KFP14021.1 - 9.7e-63 211.1 0.0 1.6e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP14021.1 - 1.9e-46 158.3 1.8 1.5e-44 152.1 1.8 2.3 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KFP14021.1 - 7e-08 32.6 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding DUF4207 PF13904.6 KFP14022.1 - 2.1 8.0 79.7 0.22 11.2 59.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) 7tm_1 PF00001.21 KFP14023.1 - 1.9e-54 184.7 14.3 2.5e-54 184.4 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14023.1 - 6.3e-15 55.2 13.3 8.8e-15 54.8 13.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP14023.1 - 2.3e-06 27.4 8.0 2.3e-06 27.4 8.0 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP14023.1 - 7.2e-05 22.6 15.0 0.00011 22.1 15.0 1.2 1 0 0 1 1 1 1 Olfactory receptor DUF5409 PF17421.2 KFP14023.1 - 0.72 10.6 0.1 0.72 10.6 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5409) RRM_1 PF00076.22 KFP14026.1 - 1.9e-36 123.7 2.1 7.9e-14 51.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KFP14026.1 - 1.4e-24 86.1 0.0 4e-24 84.7 0.0 1.8 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 KFP14026.1 - 2.4e-06 27.6 2.6 0.035 14.2 0.1 4.0 2 2 1 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFP14026.1 - 0.014 15.0 0.1 5.8 6.5 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AtuA PF07287.11 KFP14027.1 - 6.5e-107 357.3 0.0 7.6e-107 357.1 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fib_alpha PF08702.10 KFP14028.1 - 8.8e-41 139.4 1.9 8.8e-41 139.4 1.9 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family TGF_beta PF00019.20 KFP14028.1 - 0.026 15.5 0.2 0.13 13.3 0.1 2.0 2 0 0 2 2 2 0 Transforming growth factor beta like domain BST2 PF16716.5 KFP14028.1 - 0.032 14.8 3.7 0.84 10.3 0.1 3.5 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 NICE-3 PF07406.11 KFP14028.1 - 0.071 13.1 0.4 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 NICE-3 protein Fibrinogen_C PF00147.18 KFP14029.1 - 4.2e-101 337.4 14.7 5.8e-101 336.9 14.7 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 KFP14029.1 - 2.3e-43 147.8 4.9 3e-43 147.4 4.9 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KFP14029.1 - 0.0023 18.2 8.8 0.0051 17.1 4.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF1465 PF07323.12 KFP14029.1 - 0.0024 17.7 2.0 0.085 12.7 0.5 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1465) PI3K_P85_iSH2 PF16454.5 KFP14029.1 - 0.049 13.2 2.3 0.083 12.5 2.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EF-hand_6 PF13405.6 KFP14029.1 - 0.071 13.1 0.2 0.64 10.1 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain DUF1664 PF07889.12 KFP14029.1 - 0.11 12.5 2.6 0.31 11.1 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 KFP14029.1 - 0.16 11.8 7.9 0.64 9.8 2.3 2.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) WD40 PF00400.32 KFP14030.1 - 1e-40 136.9 20.8 2e-09 37.9 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14030.1 - 1.7e-05 25.0 4.6 0.25 11.7 0.1 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP14030.1 - 9.1e-05 21.4 0.6 0.73 8.5 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.6 KFP14030.1 - 0.0012 18.9 0.1 6 7.0 0.0 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KFP14030.1 - 0.0035 16.1 4.1 0.51 8.9 0.4 3.8 1 1 3 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFP14030.1 - 0.062 12.6 0.0 0.28 10.5 0.0 2.0 2 1 1 3 3 3 0 WD40-like domain Lectin_C PF00059.21 KFP14031.1 - 1.8e-13 51.1 4.9 1.8e-13 51.1 4.9 1.9 2 0 0 2 2 2 1 Lectin C-type domain Ly49 PF08391.10 KFP14031.1 - 0.016 15.6 0.1 0.028 14.8 0.1 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region TMEM52 PF14979.6 KFP14032.1 - 3.4e-61 205.5 0.1 4e-61 205.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane 52 Herpes_LMP2 PF07415.11 KFP14032.1 - 0.082 11.7 0.6 0.13 11.0 0.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein UL42 PF17638.2 KFP14032.1 - 0.16 12.0 1.1 1.1 9.2 0.3 2.1 2 0 0 2 2 2 0 HCMV UL42 DUF2892 PF11127.8 KFP14032.1 - 0.74 9.9 4.2 1.2 9.2 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Atg8 PF02991.16 KFP14033.1 - 2.2e-48 162.7 0.1 2.6e-48 162.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFP14033.1 - 3.9e-08 33.6 0.0 4.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 VitD-bind_III PF09164.10 KFP14033.1 - 0.16 12.0 0.3 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Pkinase_Tyr PF07714.17 KFP14034.1 - 1.4e-66 224.5 0.0 2.2e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP14034.1 - 5.2e-33 114.5 0.0 8.9e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFP14034.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EphA2_TM PF14575.6 KFP14034.1 - 0.045 14.6 0.0 0.092 13.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 KFP14034.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Synaptonemal_3 PF15191.6 KFP14035.1 - 1.2e-34 118.0 5.9 1.3e-34 117.9 5.9 1.0 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 Bap31_Bap29_C PF18035.1 KFP14035.1 - 0.026 14.5 0.3 0.026 14.5 0.3 1.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mis14 PF08641.12 KFP14035.1 - 0.053 13.8 0.4 0.086 13.2 0.1 1.6 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Spore_YhcN_YlaJ PF09580.10 KFP14035.1 - 0.093 12.8 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Pkinase PF00069.25 KFP14036.1 - 5.4e-52 176.8 0.5 1.3e-51 175.5 0.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14036.1 - 7.3e-19 68.1 0.1 9.5e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP14036.1 - 0.00018 21.5 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP14036.1 - 0.0036 16.9 0.0 0.0081 15.8 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFP14036.1 - 0.01 15.4 0.8 0.015 14.8 0.8 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KFP14036.1 - 0.023 14.0 0.1 0.14 11.5 0.0 1.9 1 1 1 2 2 2 0 Kinase-like RAD51_interact PF15696.5 KFP14038.1 - 7.3e-21 74.0 2.9 7.3e-21 74.0 2.9 2.1 3 0 0 3 3 3 1 RAD51 interacting motif DUF2362 PF10154.9 KFP14039.1 - 6.2e-218 724.8 14.9 7.1e-218 724.6 14.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) FGF PF00167.18 KFP14040.1 - 1.5e-41 141.4 0.0 2e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.18 KFP14041.1 - 9e-22 77.5 0.0 1.3e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Cyclin_N PF00134.23 KFP14042.1 - 1.4e-36 125.1 1.1 2.6e-36 124.1 1.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP14042.1 - 2e-21 76.3 0.0 6.8e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 KFP14042.1 - 0.046 14.1 0.0 0.081 13.4 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal SbcD_C PF12320.8 KFP14042.1 - 0.094 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain 3Beta_HSD PF01073.19 KFP14044.1 - 2.8e-11 43.0 0.0 5.1e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP14044.1 - 3e-11 43.2 0.0 9.4e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFP14044.1 - 1.6e-08 34.4 0.0 1.4e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFP14044.1 - 1.4e-07 31.5 0.0 3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFP14044.1 - 4.3e-07 29.3 0.0 3.6e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFP14044.1 - 0.00026 20.2 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KFP14044.1 - 0.032 13.6 0.0 0.17 11.3 0.0 2.0 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase Ion_trans PF00520.31 KFP14045.1 - 1.7e-51 174.8 0.1 2.3e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP14045.1 - 1.2e-12 47.6 7.0 1.2e-12 47.6 7.0 2.6 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP14045.1 - 0.004 15.9 2.6 0.0086 14.8 2.6 1.6 1 1 0 1 1 1 1 Polycystin cation channel DUF423 PF04241.15 KFP14045.1 - 0.83 9.9 3.5 0.84 9.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF973 PF06157.11 KFP14045.1 - 1.4 7.9 8.1 0.11 11.6 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Sigma_reg_N PF13800.6 KFP14045.1 - 3.8 7.9 6.2 7.6 6.9 0.1 3.3 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFP14046.1 - 2.9e-52 177.3 11.1 4.1e-52 176.9 11.1 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP14046.1 - 1.5e-28 99.0 0.3 3.7e-28 97.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP14046.1 - 6.2e-14 51.7 5.2 6.2e-14 51.7 5.2 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP14046.1 - 0.012 14.4 0.5 0.012 14.4 0.5 1.8 1 1 1 2 2 2 0 Polycystin cation channel Sigma_reg_N PF13800.6 KFP14046.1 - 0.16 12.2 8.1 4.6 7.6 0.1 3.8 3 1 0 3 3 3 0 Sigma factor regulator N-terminal DUF423 PF04241.15 KFP14046.1 - 5 7.4 4.9 1.3 9.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) ELO PF01151.18 KFP14047.1 - 1.2e-63 214.9 23.4 1.4e-63 214.8 23.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.8 KFP14047.1 - 0.15 12.0 2.8 0.78 9.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ion_trans PF00520.31 KFP14048.1 - 1.8e-54 184.5 0.3 2.4e-54 184.2 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP14048.1 - 2.6e-23 82.2 0.1 4.6e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP14048.1 - 3.4e-14 52.6 4.1 3.4e-14 52.6 4.1 2.3 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KFP14048.1 - 0.00085 18.1 0.9 0.0019 16.9 0.9 1.5 1 0 0 1 1 1 1 Polycystin cation channel Sigma_reg_N PF13800.6 KFP14048.1 - 0.21 11.9 1.0 7.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal NGF PF00243.18 KFP14049.1 - 8.6e-52 174.1 3.7 1.6e-51 173.3 3.7 1.4 1 0 0 1 1 1 1 Nerve growth factor family Spaetzle PF16077.5 KFP14049.1 - 0.0006 20.3 0.5 0.0006 20.3 0.5 1.7 2 0 0 2 2 2 1 Spaetzle GPAT_N PF14829.6 KFP14049.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Anoctamin PF04547.12 KFP14050.1 - 1.7e-156 521.6 12.2 2.1e-156 521.3 12.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP14050.1 - 1.3e-78 263.8 0.0 1.3e-78 263.8 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin VWD PF00094.25 KFP14051.1 - 6.5e-118 390.4 17.9 8.3e-36 123.6 0.1 4.7 4 0 0 4 4 4 4 von Willebrand factor type D domain VWA PF00092.28 KFP14051.1 - 8.6e-91 302.9 9.3 1.4e-36 126.4 0.4 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain C8 PF08742.11 KFP14051.1 - 1.1e-55 185.9 56.0 1.1e-18 67.5 5.8 9.2 8 0 0 8 8 8 4 C8 domain VWA_2 PF13519.6 KFP14051.1 - 1.7e-30 105.8 1.5 8.4e-11 42.5 0.1 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain TIL PF01826.17 KFP14051.1 - 1.7e-28 98.6 111.3 6.2e-12 45.6 18.3 19.9 18 3 3 21 21 21 5 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFP14051.1 - 2.9e-09 37.1 57.1 9e-06 25.9 14.1 21.0 15 4 5 20 20 20 6 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFP14051.1 - 0.0033 17.1 7.2 0.0033 17.1 7.2 12.6 15 0 0 15 15 15 2 Pacifastin inhibitor (LCMII) MCR_beta_N PF02783.15 KFP14051.1 - 0.039 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Tetraspanin PF00335.20 KFP14052.1 - 4e-37 128.1 12.2 5e-37 127.8 12.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 KFP14052.1 - 0.12 11.1 5.0 0.48 9.1 1.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Homeodomain PF00046.29 KFP14053.1 - 4.1e-23 81.0 2.2 5.6e-23 80.6 2.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP14053.1 - 0.00042 20.2 0.1 0.0011 18.8 0.1 1.7 2 0 0 2 2 2 1 Homeobox KN domain HTH_28 PF13518.6 KFP14053.1 - 0.039 14.1 0.1 0.068 13.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1510 PF07423.11 KFP14053.1 - 0.047 13.8 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) DUF1323 PF07037.11 KFP14053.1 - 0.049 14.0 0.3 0.078 13.4 0.3 1.3 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) DUF4588 PF15251.6 KFP14053.1 - 0.12 12.1 1.5 0.18 11.5 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4588) zf-C2H2 PF00096.26 KFP14054.1 - 6e-06 26.4 1.3 0.0018 18.6 0.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP14054.1 - 0.00017 22.1 1.3 0.094 13.6 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KFP14054.1 - 0.042 13.8 5.8 0.091 12.7 2.8 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 KFP14055.1 - 4.9e-66 216.4 63.1 6.8e-09 35.8 0.6 8.9 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFP14055.1 - 1.6e-52 173.2 77.5 1e-07 32.0 0.5 8.3 9 0 0 9 9 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP14055.1 - 1e-31 106.9 63.8 4e-05 24.1 0.4 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf_UBZ PF18439.1 KFP14055.1 - 1.6e-15 56.4 32.9 0.068 12.8 0.1 8.2 8 0 0 8 8 8 8 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP14055.1 - 1.2e-11 44.5 36.8 0.0058 16.7 1.7 5.8 3 2 3 6 6 6 6 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP14055.1 - 5.3e-10 39.3 30.1 0.074 13.4 0.3 7.3 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KFP14055.1 - 2.8e-08 33.5 36.8 0.21 11.5 0.2 8.3 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 KFP14055.1 - 5.6e-08 32.4 44.8 0.00056 19.6 0.5 8.1 8 0 0 8 8 8 3 zinc-finger C2H2-type C1_1 PF00130.22 KFP14055.1 - 4.8e-07 29.6 30.0 0.19 11.7 0.8 6.4 1 1 7 8 8 8 6 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.6 KFP14055.1 - 1.5e-06 28.0 30.9 2.8 7.9 0.2 8.1 8 0 0 8 8 8 2 Probable zinc-ribbon domain XPA_N PF01286.18 KFP14055.1 - 5.1e-06 26.4 31.1 2.1 8.5 0.3 8.1 8 0 0 8 8 8 3 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFP14055.1 - 6.7e-06 26.8 29.0 0.015 16.0 1.5 4.7 1 1 6 7 7 7 7 zinc-ribbon family DZR PF12773.7 KFP14055.1 - 1.5e-05 24.9 35.9 0.26 11.3 7.1 5.1 1 1 1 2 2 1 1 Double zinc ribbon FYDLN_acid PF09538.10 KFP14055.1 - 2.4e-05 24.9 20.2 5.1 7.8 0.0 7.3 1 1 4 6 6 6 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 KFP14055.1 - 4.6e-05 23.5 32.6 0.23 11.7 3.1 5.8 1 1 4 6 6 6 3 LIM domain DNA_RNApol_7kD PF03604.13 KFP14055.1 - 8.3e-05 22.2 36.4 3 7.6 0.1 8.1 7 1 0 7 7 7 2 DNA directed RNA polymerase, 7 kDa subunit zf-met PF12874.7 KFP14055.1 - 0.00051 20.3 51.3 0.049 14.0 0.6 7.7 8 0 0 8 8 7 4 Zinc-finger of C2H2 type YhfH PF14149.6 KFP14055.1 - 0.00069 19.5 28.3 7.7 6.6 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein MBD PF01429.19 KFP14055.1 - 0.0015 18.2 2.5 3.6 7.4 0.0 3.7 1 1 1 3 3 3 2 Methyl-CpG binding domain HypA PF01155.19 KFP14055.1 - 0.002 18.1 27.0 1.3 9.1 1.6 4.8 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 KFP14055.1 - 0.0031 17.5 29.2 2.8 8.0 0.1 7.7 4 2 4 8 8 8 1 CpXC protein DUF3268 PF11672.8 KFP14055.1 - 0.0047 17.2 25.7 1 9.7 1.7 5.0 2 2 5 7 7 7 4 zinc-finger-containing domain ADK_lid PF05191.14 KFP14055.1 - 0.0056 16.6 36.6 0.21 11.6 2.1 6.4 2 1 4 6 6 6 2 Adenylate kinase, active site lid DUF2256 PF10013.9 KFP14055.1 - 0.0092 16.1 25.1 13 6.0 0.0 7.7 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 KFP14055.1 - 0.01 15.8 46.7 0.23 11.5 3.6 5.7 3 3 4 7 7 7 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 KFP14055.1 - 0.011 16.0 36.2 0.46 10.8 3.3 5.6 1 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFP14055.1 - 0.018 14.7 37.9 0.76 9.5 0.7 7.3 1 1 7 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain Yippee-Mis18 PF03226.14 KFP14055.1 - 0.029 14.6 26.7 1.3 9.2 0.8 5.6 3 2 2 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_6 PF13912.6 KFP14055.1 - 0.031 14.3 0.3 0.031 14.3 0.3 9.1 8 3 0 8 8 8 0 C2H2-type zinc finger OSTMP1 PF09777.9 KFP14055.1 - 0.059 12.8 13.7 0.72 9.2 11.8 2.7 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-AN1 PF01428.16 KFP14055.1 - 0.29 11.3 49.2 1.1 9.4 0.2 8.2 5 2 3 8 8 8 0 AN1-like Zinc finger DUF2072 PF09845.9 KFP14055.1 - 0.35 11.1 33.3 2 8.6 0.5 7.2 5 3 2 7 7 7 0 Zn-ribbon containing protein C1_4 PF07975.12 KFP14055.1 - 0.67 10.2 35.0 0.39 11.0 0.6 6.0 1 1 7 8 8 8 0 TFIIH C1-like domain zf-Paramyx-P PF13008.7 KFP14055.1 - 1.5 8.4 29.3 14 5.3 0.3 7.7 8 0 0 8 8 8 0 Zinc-binding domain of Paramyxoviridae V protein zf_ZIC PF18366.1 KFP14055.1 - 1.7 8.8 21.7 21 5.3 0.4 6.5 3 2 4 7 7 7 0 Zic proteins zinc finger domain TFIIS_C PF01096.18 KFP14055.1 - 2.3 8.1 40.8 6.7 6.7 0.2 8.0 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 KFP14055.1 - 3.1 8.4 43.4 4.5 7.9 3.0 7.0 1 1 6 7 7 7 0 Recombinase zinc beta ribbon domain BolA PF01722.18 KFP14055.1 - 5.8 7.3 9.8 9 6.7 0.2 3.6 3 1 1 4 4 4 0 BolA-like protein DUF3447 PF11929.8 KFP14057.1 - 0.27 11.2 1.9 0.78 9.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DUF5024 PF16427.5 KFP14057.1 - 9.9 6.6 11.5 0.81 10.1 3.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5024) Parathyroid PF01279.17 KFP14059.1 - 2.9e-38 130.8 0.5 6.9e-38 129.6 0.5 1.6 1 0 0 1 1 1 1 Parathyroid hormone family RRP14 PF15459.6 KFP14059.1 - 1.6 9.4 10.9 2.8 8.6 10.9 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Kelch_1 PF01344.25 KFP14060.1 - 2.4e-29 100.6 3.7 1.8e-09 37.0 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KFP14060.1 - 2.4e-24 84.7 3.6 7.7e-08 32.4 0.0 6.1 5 2 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KFP14060.1 - 1.7e-11 43.6 0.6 0.0091 15.9 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KFP14060.1 - 1.9e-11 44.0 2.1 0.00054 20.2 0.0 5.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP14060.1 - 3.6e-11 42.8 1.1 8.6e-05 22.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFP14060.1 - 5.3e-05 23.1 5.4 0.6 10.2 0.0 5.5 5 2 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.31 KFP14060.1 - 0.001 19.3 0.0 0.028 14.7 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP14060.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch BILBO1_N PF18281.1 KFP14060.1 - 0.093 13.2 0.4 30 5.1 0.0 3.8 4 0 0 4 4 4 0 BILBO1 N-terminal domain MANEC PF07502.14 KFP14061.1 - 1.2e-06 28.7 3.3 1.2e-06 28.7 3.3 1.8 2 0 0 2 2 2 1 MANEC domain CiPC PF15800.5 KFP14061.1 - 0.3 10.8 16.0 0.4 10.3 16.0 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian MRP-S28 PF10213.9 KFP14062.1 - 8.9e-19 68.2 0.2 1.4e-18 67.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CDI PF02234.19 KFP14063.1 - 8.5e-22 77.1 5.8 4.1e-21 74.9 3.0 2.4 2 0 0 2 2 2 2 Cyclin-dependent kinase inhibitor CDI PF02234.19 KFP14064.1 - 1.4e-18 66.8 0.6 1.5e-18 66.7 0.6 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Coat_F PF07875.12 KFP14064.1 - 0.038 14.2 0.2 0.055 13.7 0.2 1.2 1 0 0 1 1 1 0 Coat F domain CDI PF02234.19 KFP14065.1 - 1.6e-17 63.4 0.5 1.8e-17 63.2 0.5 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Coat_F PF07875.12 KFP14065.1 - 0.039 14.2 0.2 0.055 13.7 0.2 1.2 1 0 0 1 1 1 0 Coat F domain 7tm_1 PF00001.21 KFP14066.1 - 3.6e-43 147.8 16.3 4.5e-43 147.5 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14066.1 - 2.8e-08 33.5 18.3 3.9e-08 33.0 18.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP14066.1 - 2e-05 24.5 11.9 0.00089 19.1 11.9 2.4 1 1 0 1 1 1 1 Olfactory receptor AGTRAP PF06396.11 KFP14066.1 - 0.13 12.0 2.9 0.17 11.7 0.1 2.3 2 1 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF5083 PF16890.5 KFP14066.1 - 0.8 9.4 8.3 0.71 9.6 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) bZIP_2 PF07716.15 KFP14067.1 - 1.7e-08 34.4 7.8 2.5e-08 33.8 7.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP14067.1 - 7e-05 22.9 6.7 0.00012 22.1 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor DSPc PF00782.20 KFP14068.1 - 8.5e-44 148.6 0.0 1.7e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFP14068.1 - 1.8e-16 60.6 0.0 1e-15 58.2 0.0 2.3 3 0 0 3 3 3 1 Rhodanese-like domain Y_phosphatase PF00102.27 KFP14068.1 - 0.00015 21.4 0.1 0.00039 20.1 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase zf-RING_14 PF17978.1 KFP14068.1 - 0.0093 16.4 0.3 0.18 12.2 0.0 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Init_tRNA_PT PF04179.12 KFP14068.1 - 0.079 13.3 0.5 0.66 10.3 0.0 2.4 2 0 0 2 2 2 0 Rit1 DUSP-like domain LOH1CR12 PF10158.9 KFP14069.1 - 9.8e-57 190.6 1.8 1.2e-56 190.3 1.8 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.12 KFP14069.1 - 0.0024 17.9 1.4 0.0036 17.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RE_Bpu10I PF09549.10 KFP14069.1 - 0.0054 16.4 0.2 0.0071 16.0 0.2 1.2 1 0 0 1 1 1 1 Bpu10I restriction endonuclease BLOC1_2 PF10046.9 KFP14069.1 - 0.029 14.7 0.7 0.056 13.7 0.7 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 POX PF07526.11 KFP14069.1 - 0.45 11.1 4.2 0.72 10.4 4.2 1.5 1 1 0 1 1 1 0 Associated with HOX MANEC PF07502.14 KFP14070.1 - 3.4e-18 65.7 0.6 6.1e-18 64.9 0.6 1.4 1 0 0 1 1 1 1 MANEC domain DUF5585 PF17823.1 KFP14070.1 - 5.7e-06 25.6 0.1 5.7e-06 25.6 0.1 2.6 1 1 1 2 2 2 1 Family of unknown function (DUF5585) PAN_4 PF14295.6 KFP14070.1 - 0.083 12.8 1.7 0.23 11.4 1.7 1.7 1 1 0 1 1 1 0 PAN domain Ldl_recept_b PF00058.17 KFP14071.1 - 8.3e-155 503.1 44.4 1.9e-13 50.7 0.1 20.4 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP14071.1 - 2.6e-40 136.4 64.9 1.9e-11 44.0 5.9 5.7 5 1 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.18 KFP14071.1 - 1.4e-31 108.4 48.4 6.1e-11 42.4 8.3 3.8 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A DUF5050 PF16472.5 KFP14071.1 - 4.3e-20 72.1 0.0 0.00012 21.4 0.0 6.5 4 3 2 7 7 7 5 Domain of unknown function (DUF5050) SGL PF08450.12 KFP14071.1 - 2.5e-17 63.3 19.3 0.019 14.5 0.0 11.9 6 4 5 12 12 12 6 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFP14071.1 - 0.00096 19.0 1.2 0.00096 19.0 1.2 5.2 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.27 KFP14071.1 - 0.22 11.9 69.3 0.096 13.0 7.8 6.3 6 0 0 6 6 6 0 EGF-like domain YoeB_toxin PF06769.14 KFP14071.1 - 0.26 11.4 2.7 43 4.2 0.1 4.2 4 0 0 4 4 4 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Bcl-2 PF00452.19 KFP14072.1 - 3.8e-05 24.3 0.0 0.00011 22.8 0.0 1.9 1 1 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family CF222 PF15661.5 KFP14072.1 - 0.00021 20.3 1.0 0.00036 19.6 1.0 1.3 1 0 0 1 1 1 1 C6orf222, uncharacterised family DUF1779 PF08680.10 KFP14072.1 - 0.01 16.1 0.3 0.021 15.0 0.0 1.6 2 0 0 2 2 2 0 TATA-box binding Ashwin PF15323.6 KFP14072.1 - 0.023 14.8 1.3 0.036 14.1 1.3 1.3 1 0 0 1 1 1 0 Developmental protein BID PF06393.11 KFP14072.1 - 0.031 13.8 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) EcpB_C PF18649.1 KFP14072.1 - 0.07 13.1 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 EcpB C-terminal domain Ets PF00178.22 KFP14073.1 - 2.4e-30 104.8 1.5 5.3e-30 103.7 1.5 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP14073.1 - 6.3e-27 93.4 0.0 1.1e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFP14073.1 - 0.0006 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP14073.1 - 0.12 12.8 0.6 0.38 11.2 0.6 1.9 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) PARP PF00644.20 KFP14074.1 - 5.5e-41 140.3 0.6 1.4e-40 139.0 0.6 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 KFP14074.1 - 3.2e-16 59.7 5.7 4.4e-15 56.0 0.8 2.7 2 0 0 2 2 2 1 WWE domain zf_CCCH_4 PF18345.1 KFP14074.1 - 0.00068 19.6 6.2 0.00068 19.6 6.2 3.8 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_8 PF18633.1 KFP14074.1 - 0.00079 19.5 3.6 0.00079 19.5 3.6 3.0 3 0 0 3 3 3 1 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 zf-CCCH_4 PF18044.1 KFP14074.1 - 0.079 12.8 0.5 0.079 12.8 0.5 3.7 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 KFP14074.1 - 0.21 12.3 9.3 0.24 12.1 0.3 2.9 2 0 0 2 2 2 0 Torus domain TPR_14 PF13428.6 KFP14075.1 - 3.2e-05 24.4 0.2 8.8 7.4 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP14075.1 - 0.00056 19.4 3.3 0.0078 15.6 0.3 3.2 2 1 1 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 KFP14075.1 - 0.0075 16.8 0.2 7.7 7.4 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP14075.1 - 0.014 15.4 9.1 7.1 7.0 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP14075.1 - 0.13 12.2 0.2 2.1 8.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PKD_channel PF08016.12 KFP14076.1 - 7e-115 384.1 11.6 7e-115 384.1 11.6 2.3 2 0 0 2 2 2 1 Polycystin cation channel REJ PF02010.15 KFP14076.1 - 1.7e-89 300.7 0.0 2.6e-89 300.1 0.0 1.2 1 0 0 1 1 1 1 REJ domain PLAT PF01477.23 KFP14076.1 - 3.2e-21 76.1 0.0 9.9e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 PLAT/LH2 domain Ion_trans PF00520.31 KFP14076.1 - 2.3e-07 30.3 22.9 2.3e-07 30.3 22.9 2.5 3 0 0 3 3 3 1 Ion transport protein GPS PF01825.21 KFP14076.1 - 0.11 13.0 2.1 0.29 11.7 2.1 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif RVT_1 PF00078.27 KFP14077.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP14077.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase BUD22 PF09073.10 KFP14078.1 - 9.8e-10 38.3 58.8 5.8e-08 32.5 15.1 2.9 1 1 1 2 2 2 2 BUD22 GTSE1_N PF15259.6 KFP14078.1 - 0.0016 18.7 4.9 0.0016 18.7 4.9 3.0 2 1 0 2 2 2 1 G-2 and S-phase expressed 1 Lysyl_oxidase PF01186.17 KFP14079.1 - 4.9e-93 310.5 4.0 5.5e-93 310.3 4.0 1.0 1 0 0 1 1 1 1 Lysyl oxidase BsuPI PF12690.7 KFP14079.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor zf-C2HC_2 PF13913.6 KFP14080.1 - 3.1e-16 58.8 11.5 1.3e-08 34.5 1.3 2.9 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KFP14080.1 - 0.0016 18.8 2.0 0.54 10.8 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 KFP14080.1 - 0.0046 16.9 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_4 PF13894.6 KFP14080.1 - 0.006 17.3 6.7 2.6 9.1 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger c-SKI_SMAD_bind PF08782.10 KFP14080.1 - 0.015 15.5 1.9 0.03 14.6 0.0 2.0 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Vps36-NZF-N PF16988.5 KFP14080.1 - 0.028 13.8 1.5 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Rad50_zn_hook PF04423.14 KFP14080.1 - 0.044 13.6 0.2 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif IgGFc_binding PF17517.2 KFP14080.1 - 0.087 12.1 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 IgGFc binding protein RNHCP PF12647.7 KFP14080.1 - 0.18 11.8 4.4 1.7 8.6 0.5 2.8 1 1 1 2 2 2 0 RNHCP domain zf_C2H2_13 PF18508.1 KFP14080.1 - 1.8 8.2 5.8 4.9 6.8 1.3 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-C2HC_2 PF13913.6 KFP14081.1 - 4.4e-18 64.7 3.8 1.5e-10 40.7 0.4 2.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KFP14081.1 - 0.0038 17.6 1.8 0.051 14.1 0.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-CpG_bind_C PF12269.8 KFP14081.1 - 0.0066 16.3 0.4 1.1 9.0 0.1 2.0 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain zf-PHD-like PF15446.6 KFP14081.1 - 0.016 14.9 0.3 0.02 14.5 0.3 1.0 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF2318 PF10080.9 KFP14081.1 - 0.016 15.3 0.4 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) c-SKI_SMAD_bind PF08782.10 KFP14081.1 - 0.016 15.4 1.1 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 c-SKI Smad4 binding domain PHD PF00628.29 KFP14081.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.4 2 1 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KFP14081.1 - 0.031 14.4 3.9 0.5 10.5 0.1 2.8 2 1 1 3 3 3 0 PHD-finger zf-C2H2_4 PF13894.6 KFP14081.1 - 0.041 14.7 4.9 0.27 12.2 0.6 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KFP14081.1 - 0.079 13.0 0.7 13 5.9 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger Zf_RING PF16744.5 KFP14081.1 - 0.43 10.7 3.2 1.6 8.9 0.1 2.2 2 1 0 2 2 2 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 KFP14081.1 - 1.6 8.7 7.0 0.76 9.8 0.2 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 SNCAIP_SNCA_bd PF16700.5 KFP14082.1 - 6.1e-25 86.7 8.4 1.9e-24 85.1 8.4 1.9 1 0 0 1 1 1 1 Synphilin-1 alpha-Synuclein-binding domain Ank_2 PF12796.7 KFP14082.1 - 5.8e-24 84.5 5.0 6.2e-12 45.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP14082.1 - 1.3e-15 57.5 0.4 9.1e-07 29.3 0.0 3.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP14082.1 - 6.3e-13 48.7 0.3 0.00029 21.1 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP14082.1 - 1e-06 28.9 2.9 0.00036 20.8 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFP14082.1 - 2.1e-05 24.6 0.6 0.53 11.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Vps5 PF09325.10 KFP14083.1 - 2.9e-84 282.3 18.8 2.9e-84 282.3 18.8 1.4 2 0 0 2 2 1 1 Vps5 C terminal like PX PF00787.24 KFP14083.1 - 4e-30 104.1 0.3 8e-29 99.9 0.1 2.4 2 0 0 2 2 2 1 PX domain Sorting_nexin PF03700.13 KFP14083.1 - 9.2e-17 61.8 2.7 2.6e-16 60.3 2.7 1.8 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain Spc7 PF08317.11 KFP14083.1 - 0.0017 17.3 16.5 0.046 12.6 3.5 2.4 2 0 0 2 2 2 2 Spc7 kinetochore protein BAR_3_WASP_bdg PF10456.9 KFP14083.1 - 0.028 13.9 7.2 0.84 9.1 7.2 2.5 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF4618 PF15397.6 KFP14083.1 - 0.16 11.3 13.4 0.11 11.9 1.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF241 PF03087.14 KFP14083.1 - 0.24 11.2 10.7 0.084 12.7 0.9 2.6 1 1 2 3 3 3 0 Arabidopsis protein of unknown function DUF3138 PF11336.8 KFP14083.1 - 0.26 9.8 4.8 0.42 9.2 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.9 KFP14083.1 - 0.34 11.2 14.4 0.19 12.1 1.0 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3775 PF12616.8 KFP14083.1 - 0.51 10.4 2.9 0.59 10.2 0.0 2.6 3 0 0 3 3 1 0 Protein of unknown function (DUF3775) HMMR_N PF15905.5 KFP14083.1 - 0.61 9.5 17.5 0.064 12.7 0.8 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Csm2_III-A PF03750.13 KFP14083.1 - 1.6 9.6 9.0 1.1 10.1 1.8 3.1 2 1 1 3 3 3 0 Csm2 Type III-A DUF2203 PF09969.9 KFP14083.1 - 1.7 9.4 10.3 4.8 7.9 1.6 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HR1 PF02185.16 KFP14083.1 - 2.1 8.6 13.4 0.89 9.7 0.6 3.5 3 0 0 3 3 3 0 Hr1 repeat Exonuc_VII_L PF02601.15 KFP14083.1 - 2.6 7.5 18.7 0.64 9.5 6.5 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit GrpE PF01025.19 KFP14083.1 - 2.9 7.5 17.5 0.27 10.9 6.1 2.6 2 0 0 2 2 2 0 GrpE Allexi_40kDa PF05549.11 KFP14083.1 - 3.4 7.1 7.9 0.62 9.5 0.7 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.22 KFP14083.1 - 3.4 7.9 15.3 9.2 6.6 3.3 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin PF00261.20 KFP14083.1 - 3.8 6.8 17.3 0.056 12.8 4.3 2.4 2 0 0 2 2 2 0 Tropomyosin DHR10 PF18595.1 KFP14083.1 - 3.9 7.6 20.3 1.6 8.8 4.4 3.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Sec34 PF04136.15 KFP14083.1 - 5.1 7.0 12.9 7.3 6.5 4.5 3.1 2 1 0 2 2 2 0 Sec34-like family Phage_HK97_TLTM PF06120.11 KFP14083.1 - 6.5 5.9 13.1 6.8 5.8 2.2 2.2 2 0 0 2 2 2 0 Tail length tape measure protein FlaC_arch PF05377.11 KFP14083.1 - 6.5 7.2 6.7 52 4.3 0.2 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PX PF00787.24 KFP14084.1 - 4.7e-14 52.3 3.3 1.4e-13 50.8 2.6 1.8 1 1 1 2 2 2 2 PX domain DUF99 PF01949.16 KFP14084.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 Pro_isomerase PF00160.21 KFP14085.1 - 1.3e-47 162.0 0.1 1.5e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 KFP14086.1 - 2.4e-13 49.7 19.6 1.9e-05 24.9 0.1 4.2 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP14086.1 - 6.6e-12 45.2 13.0 0.00012 22.6 1.5 4.4 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP14086.1 - 2.3e-10 40.4 14.7 0.0015 18.9 0.2 4.6 4 0 0 4 4 4 3 Zinc-finger double domain SET PF00856.28 KFP14086.1 - 1.8e-07 31.7 0.1 7.6e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 SET domain zf-C2H2_jaz PF12171.8 KFP14086.1 - 0.00031 20.9 0.3 0.037 14.3 0.0 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFP14086.1 - 0.021 15.3 5.4 2.4 8.7 0.0 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFP14086.1 - 0.033 14.0 1.1 0.033 14.0 1.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain UPF0113_N PF17833.1 KFP14086.1 - 0.13 12.8 0.0 0.49 11.0 0.0 1.9 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain Zn_ribbon_SprT PF17283.2 KFP14086.1 - 0.14 12.1 7.3 0.75 9.8 1.9 3.4 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF629 PF04780.12 KFP14086.1 - 0.2 10.1 11.1 1.6 7.2 3.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 KFP14086.1 - 0.33 10.7 11.0 0.55 10.0 0.1 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFP14086.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFP14086.1 - 0.42 10.5 3.1 3.2 7.7 0.0 3.0 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 KFP14086.1 - 0.56 10.6 4.9 19 5.6 0.0 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KFP14086.1 - 0.67 9.9 5.9 9.9 6.2 0.3 3.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-CHCC PF10276.9 KFP14086.1 - 2.9 8.0 7.2 0.61 10.2 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 KFP14086.1 - 4.3 7.4 10.5 4.9 7.3 0.3 3.6 3 1 1 4 4 4 0 BED zinc finger DUF3668 PF12416.8 KFP14087.1 - 1.2e-92 309.9 0.0 1.2e-92 309.9 0.0 2.6 2 0 0 2 2 2 1 Cep120 protein C2 PF00168.30 KFP14087.1 - 8.4e-09 35.7 0.0 0.0091 16.3 0.0 3.5 3 0 0 3 3 3 3 C2 domain CK1gamma_C PF12605.8 KFP14088.1 - 6.2e-31 107.5 5.0 1e-30 106.8 5.0 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.25 KFP14088.1 - 3.9e-26 92.0 0.0 5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14088.1 - 1.3e-13 50.9 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP14088.1 - 1.2e-07 30.9 1.0 1.3e-07 30.8 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase RVT_1 PF00078.27 KFP14092.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM27 PF15832.5 KFP14094.1 - 1.9 9.1 13.9 2.4 8.7 5.7 3.9 3 0 0 3 3 3 0 FAM27 D and E protein family GRAM PF02893.20 KFP14099.1 - 3.6e-18 65.5 0.1 7.2e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Plasmodium_Vir PF05795.11 KFP14099.1 - 0.026 14.0 0.2 0.042 13.3 0.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Aldedh PF00171.22 KFP14100.1 - 7.1e-127 423.7 0.0 7.9e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KFP14100.1 - 0.073 13.1 0.3 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated zf-RING_UBOX PF13445.6 KFP14106.1 - 2.2e-08 34.0 2.6 2.2e-08 34.0 2.6 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 KFP14106.1 - 4.3e-06 26.8 6.9 4.3e-06 26.8 6.9 4.3 4 1 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 KFP14106.1 - 9.3e-06 25.4 4.5 9.3e-06 25.4 4.5 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP14106.1 - 2e-05 24.7 4.6 2e-05 24.7 4.6 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING fn3 PF00041.21 KFP14106.1 - 8.9e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.6 KFP14106.1 - 0.00029 20.6 4.3 0.00029 20.6 4.3 4.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP14106.1 - 0.0023 17.8 2.7 0.0023 17.8 2.7 4.4 3 1 0 3 3 3 1 zinc-RING finger domain SPRY PF00622.28 KFP14106.1 - 0.0086 16.2 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 SPRY domain zf-CRD PF17979.1 KFP14106.1 - 0.015 15.4 2.0 0.015 15.4 2.0 3.5 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions CaMBD PF02888.16 KFP14107.1 - 7.5e-39 131.8 12.3 1.8e-38 130.6 10.7 2.2 2 0 0 2 2 2 1 Calmodulin binding domain SK_channel PF03530.14 KFP14107.1 - 4.7e-30 103.9 0.7 4.7e-30 103.9 0.7 2.5 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 KFP14107.1 - 8.2e-14 51.3 3.2 3.1e-13 49.5 3.2 2.0 1 0 0 1 1 1 1 Ion channel Med9 PF07544.13 KFP14107.1 - 0.0037 17.3 0.6 0.0037 17.3 0.6 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 IRK PF01007.20 KFP14107.1 - 0.18 11.6 5.0 0.17 11.7 2.4 2.2 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Prefoldin_2 PF01920.20 KFP14107.1 - 1.1 9.2 12.3 13 5.8 7.1 3.3 1 1 1 2 2 2 0 Prefoldin subunit FERM_C PF09380.10 KFP14110.1 - 9.8e-26 90.0 0.3 2.1e-25 88.9 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP14110.1 - 6.8e-15 55.5 0.1 1.3e-14 54.6 0.1 1.5 1 0 0 1 1 1 1 FERM central domain FA PF08736.11 KFP14110.1 - 7.2e-13 48.4 4.7 1.4e-12 47.5 2.4 2.3 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.10 KFP14110.1 - 2.5e-09 36.9 0.0 6.1e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain Pkinase PF00069.25 KFP14111.1 - 2.6e-72 243.3 0.0 3.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14111.1 - 4.4e-54 183.5 0.0 5.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP14111.1 - 2.7e-05 23.1 0.0 4.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP14111.1 - 0.0036 16.7 0.1 0.039 13.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP14111.1 - 0.013 14.5 0.1 0.54 9.1 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP14111.1 - 0.033 14.1 0.0 5.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP14111.1 - 0.065 12.6 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ssDNA_DBD PF18333.1 KFP14111.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain IL6Ra-bind PF09240.10 KFP14112.1 - 1.7e-18 66.9 0.4 3.4e-18 65.8 0.4 1.6 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP14112.1 - 9.8e-08 32.2 0.6 2.8e-07 30.7 0.6 1.7 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.17 KFP14112.1 - 6.5e-05 22.7 6.3 0.01 15.7 0.5 2.6 2 1 0 2 2 2 2 Tissue factor fn3 PF00041.21 KFP14112.1 - 0.00027 21.2 0.1 0.016 15.6 0.0 2.5 2 1 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.10 KFP14112.1 - 0.059 13.7 1.9 1.3 9.4 0.6 2.6 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DHR-2 PF06920.13 KFP14113.1 - 3e-204 679.6 9.3 6e-204 678.6 9.3 1.5 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP14113.1 - 1.7e-56 191.2 0.2 3.2e-55 187.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFP14113.1 - 3.5e-42 143.4 1.9 4.5e-42 143.0 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.29 KFP14113.1 - 1.8e-11 44.5 0.6 7.6e-11 42.5 0.6 2.2 1 0 0 1 1 1 1 PH domain DUF1667 PF07892.11 KFP14113.1 - 0.011 15.7 0.1 0.043 13.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) WD40 PF00400.32 KFP14115.1 - 1.3e-24 86.0 9.1 0.00022 21.9 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14115.1 - 5.3e-06 26.6 0.1 1.7 9.0 0.0 4.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DAO_C PF16901.5 KFP14115.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase BBS2_Mid PF14783.6 KFP14115.1 - 0.089 12.8 0.1 5 7.2 0.0 3.5 2 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Kelch_1 PF01344.25 KFP14117.1 - 3.7e-56 186.5 8.5 1.2e-10 40.8 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP14117.1 - 1.4e-35 120.4 6.3 1e-07 32.0 0.0 7.1 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFP14117.1 - 1.2e-26 92.8 0.0 2.7e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFP14117.1 - 3.1e-24 85.3 0.3 1.2e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP14117.1 - 7.2e-24 82.8 5.3 3.7e-05 23.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFP14117.1 - 1.4e-23 82.6 4.0 3.3e-06 27.2 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP14117.1 - 1e-17 63.8 0.9 0.0015 18.5 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP14117.1 - 9.6e-11 41.4 13.0 0.0052 16.7 0.6 5.7 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFP14117.1 - 0.0062 17.0 5.7 9.5 6.9 0.0 5.0 6 0 0 6 6 6 1 PQQ-like domain DUF1075 PF06388.11 KFP14118.1 - 2e-37 127.9 0.1 2.6e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Pho88 PF10032.9 KFP14118.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphate transport (Pho88) SNF PF00209.18 KFP14119.1 - 2.2e-197 656.9 40.9 2.7e-197 656.6 40.9 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LRR_8 PF13855.6 KFP14120.1 - 8.5e-29 99.1 39.0 3.1e-13 49.3 7.7 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP14120.1 - 7.3e-13 48.5 36.5 4.4e-05 23.7 6.1 4.9 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP14120.1 - 2.7e-11 43.5 2.0 8.9e-11 41.9 0.6 2.0 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP14120.1 - 1.4e-07 31.0 35.8 0.28 11.9 2.7 7.3 7 0 0 7 7 7 6 Leucine Rich Repeat LRR_9 PF14580.6 KFP14120.1 - 8.4e-05 22.1 8.5 0.051 13.1 2.0 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFP14120.1 - 0.066 12.9 1.1 0.066 12.9 1.1 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain CH PF00307.31 KFP14121.1 - 1.6e-84 279.2 2.1 1.1e-25 89.9 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFP14121.1 - 2.5e-09 37.4 0.4 1.1e-08 35.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP14121.1 - 2.1e-07 30.0 2.1 3.8e-05 22.9 0.5 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFP14121.1 - 2.3e-05 24.1 0.1 0.00033 20.4 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_5 PF13202.6 KFP14121.1 - 0.00014 21.2 4.7 0.00066 19.1 0.1 3.8 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KFP14121.1 - 0.0066 16.3 3.4 0.034 14.1 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KFP14121.1 - 0.029 14.2 0.4 0.18 11.7 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair FYTT PF07078.11 KFP14122.1 - 0.0006 19.2 4.7 0.00073 19.0 4.7 1.1 1 0 0 1 1 1 1 Forty-two-three protein LRR_8 PF13855.6 KFP14123.1 - 8.3e-25 86.3 10.1 2.9e-10 39.8 1.3 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP14123.1 - 1.7e-14 53.7 18.1 0.00043 20.6 4.0 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) CH PF00307.31 KFP14123.1 - 4.3e-10 39.7 0.0 8.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFP14123.1 - 0.00024 21.2 18.5 2.8 8.8 0.3 7.7 7 1 0 7 7 7 2 Leucine Rich Repeat CDC24 PF06395.11 KFP14123.1 - 0.0088 16.3 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin LRR_6 PF13516.6 KFP14123.1 - 0.014 15.4 17.7 15 6.0 0.4 6.2 6 0 0 6 6 6 0 Leucine Rich repeat CAMSAP_CH PF11971.8 KFP14123.1 - 0.032 14.1 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain DUF4763 PF15960.5 KFP14123.1 - 0.14 11.4 13.7 0.01 15.2 6.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) LRR_9 PF14580.6 KFP14123.1 - 0.67 9.4 7.9 5.9 6.3 3.1 2.8 1 1 1 3 3 3 0 Leucine-rich repeat 7tm_1 PF00001.21 KFP14124.1 - 1.6e-64 217.8 13.5 2.2e-64 217.3 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14124.1 - 4.2e-13 49.3 14.0 1.1e-12 47.9 14.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP14124.1 - 6e-06 26.2 3.6 6e-06 26.2 3.6 2.3 2 1 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP14124.1 - 6.5e-06 26.0 11.3 6.5e-06 26.0 11.3 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pox_P21 PF05313.12 KFP14124.1 - 0.046 13.3 0.7 0.046 13.3 0.7 3.0 3 0 0 3 3 3 0 Poxvirus P21 membrane protein RseC_MucC PF04246.12 KFP14124.1 - 5.8 6.9 7.7 0.26 11.2 0.3 2.4 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC GDPD PF03009.17 KFP14127.1 - 2.6e-20 73.2 0.0 1e-19 71.3 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family 7TMR-HDED PF07697.11 KFP14127.1 - 0.17 12.0 0.2 0.24 11.5 0.2 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Guanylate_kin PF00625.21 KFP14128.1 - 2.8e-61 206.4 0.1 4.3e-61 205.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFP14128.1 - 5.7e-53 177.2 10.1 7.8e-22 77.4 0.5 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFP14128.1 - 4.1e-30 104.4 3.3 1e-29 103.1 3.3 1.7 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_6 PF17820.1 KFP14128.1 - 3.1e-19 68.6 5.2 6.3e-07 29.2 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFP14128.1 - 4.4e-13 49.3 2.5 8.4e-05 22.8 0.2 3.5 3 0 0 3 3 3 3 PDZ domain MAGUK_N_PEST PF10608.9 KFP14128.1 - 1.3e-10 41.8 0.0 3e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_1 PF00018.28 KFP14128.1 - 1.9e-08 33.8 0.0 4.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP14128.1 - 1.4e-07 31.1 0.1 4.8e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFP14128.1 - 0.00076 19.3 0.1 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SPO22 PF08631.10 KFP14129.1 - 1.4e-82 277.3 26.5 4.7e-79 265.7 5.0 3.3 3 0 0 3 3 3 3 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KFP14129.1 - 3.1e-06 27.6 1.0 0.00082 19.8 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP14129.1 - 2.4e-05 24.1 9.0 0.0064 16.5 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP14129.1 - 6.6e-05 23.1 9.3 0.23 11.8 0.8 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP14129.1 - 0.00031 20.4 7.0 0.033 14.0 0.1 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF493 PF04359.14 KFP14129.1 - 0.085 13.5 0.2 0.28 11.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF493) TPR_8 PF13181.6 KFP14129.1 - 0.093 13.0 1.8 1 9.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP14129.1 - 0.13 12.5 14.7 6.2 7.1 0.3 5.3 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KFP14129.1 - 2.3 9.2 5.3 36 5.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFP14130.1 - 1.5e-18 66.4 0.0 1.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP14130.1 - 0.037 13.9 0.0 0.093 12.6 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP14130.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 KFP14131.1 - 1e-49 169.6 20.1 1e-49 169.6 20.1 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFP14131.1 - 2.4e-34 118.8 20.4 2.4e-34 118.8 20.4 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP14131.1 - 2.8e-22 78.5 6.7 2.8e-22 78.5 6.7 4.0 4 0 0 4 4 4 1 C-terminus of AA_permease Shisa PF13908.6 KFP14131.1 - 2.2 8.5 3.7 11 6.2 1.6 2.4 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PX PF00787.24 KFP14132.1 - 7.7e-22 77.4 0.2 8.5e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 KFP14132.1 - 0.12 10.8 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase PA26 PF04636.13 KFP14133.1 - 1.1e-179 598.0 0.0 1.2e-179 597.8 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFP14133.1 - 0.002 18.2 0.0 0.0059 16.6 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Leptin PF02024.15 KFP14133.1 - 0.016 15.0 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Leptin IL6Ra-bind PF09240.10 KFP14134.1 - 5.1e-20 71.7 0.1 8.7e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP14134.1 - 7.8e-07 29.2 0.1 1.8e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFP14134.1 - 8e-06 26.1 1.2 1.3e-05 25.4 0.4 1.8 1 1 0 1 1 1 1 Fibronectin type III domain COesterase PF00135.28 KFP14135.1 - 6.9e-169 563.0 0.0 5.7e-152 507.2 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP14135.1 - 4.3e-05 23.5 0.2 0.00029 20.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Connexin PF00029.19 KFP14136.1 - 2.7e-84 282.6 17.0 7.5e-83 277.9 17.0 2.0 1 1 0 1 1 1 1 Connexin Ninjurin PF04923.12 KFP14136.1 - 0.21 11.5 2.0 0.47 10.4 0.0 2.4 2 1 0 2 2 2 0 Ninjurin RRM_1 PF00076.22 KFP14137.1 - 8.9e-32 108.7 0.1 8e-16 57.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KFP14137.1 - 5.3e-27 93.7 2.0 1.4e-26 92.4 2.0 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_7 PF16367.5 KFP14137.1 - 9.1e-05 22.5 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KFP14137.1 - 0.0078 16.1 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif Lipoprotein_18 PF06804.11 KFP14137.1 - 0.1 11.6 5.5 0.043 12.9 3.0 1.6 1 1 0 1 1 1 0 NlpB/DapX lipoprotein RRM_5 PF13893.6 KFP14137.1 - 0.11 12.1 0.0 0.5 10.0 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.22 KFP14137.1 - 2.8 6.3 5.1 4 5.8 5.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family GvpL_GvpF PF06386.11 KFP14137.1 - 3.1 7.6 15.9 5 7.0 15.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3523 PF12037.8 KFP14137.1 - 3.4 6.9 28.8 6.1 6.1 28.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CHORD PF04968.12 KFP14138.1 - 3.6e-53 178.1 20.8 3.2e-28 98.2 5.7 2.6 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFP14138.1 - 2.1e-12 47.9 0.3 3.3e-12 47.2 0.3 1.3 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.6 KFP14138.1 - 0.61 9.7 9.6 0.87 9.3 1.0 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding BTK PF00779.19 KFP14138.1 - 1.9 8.4 16.4 0.41 10.5 0.3 3.6 4 1 0 4 4 4 0 BTK motif Ras PF00071.22 KFP14139.1 - 2.1e-56 190.0 0.0 2.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14139.1 - 2.1e-23 82.8 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP14139.1 - 7.3e-10 38.6 0.0 9.6e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP14139.1 - 0.0072 15.9 0.0 0.04 13.5 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP14139.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_transf_41 PF13844.6 KFP14140.1 - 1.1e-256 851.6 0.0 1.5e-256 851.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 KFP14140.1 - 7.5e-98 316.8 28.3 2.5e-10 39.7 0.3 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 KFP14140.1 - 3.3e-90 295.5 36.1 9.1e-11 41.3 0.4 12.8 3 2 10 13 13 13 12 TPR repeat TPR_2 PF07719.17 KFP14140.1 - 1e-73 237.6 28.7 2.5e-08 33.4 0.4 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 KFP14140.1 - 3.5e-68 221.2 29.6 1.9e-05 24.7 0.1 13.7 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 KFP14140.1 - 1.9e-67 217.9 13.3 1.1e-06 28.4 0.1 13.5 14 0 0 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 KFP14140.1 - 7.6e-48 160.7 29.8 5.7e-12 45.8 1.9 9.5 6 2 5 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFP14140.1 - 7.5e-47 154.0 17.4 0.00033 21.2 0.1 12.3 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.6 KFP14140.1 - 9.8e-45 151.0 17.9 2.1e-09 37.9 0.1 7.6 6 1 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFP14140.1 - 1.9e-43 146.8 20.8 2e-07 31.4 0.6 9.2 4 4 5 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 KFP14140.1 - 4.5e-40 132.8 17.6 9.7e-05 22.1 0.1 13.0 13 1 1 14 14 13 9 Tetratricopeptide repeat TPR_10 PF13374.6 KFP14140.1 - 6.7e-36 121.2 47.6 6.9e-07 28.9 0.4 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_9 PF13371.6 KFP14140.1 - 4.2e-18 65.3 14.8 0.00079 19.5 0.4 6.9 5 1 3 8 8 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 KFP14140.1 - 1.2e-15 57.0 15.5 0.47 11.2 0.0 10.8 11 0 0 11 11 10 2 Tetratricopeptide repeat NARP1 PF12569.8 KFP14140.1 - 4.9e-15 55.4 4.7 0.0012 17.8 0.0 5.7 1 1 4 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KFP14140.1 - 5.9e-13 48.1 12.2 1.4 9.7 0.2 9.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP14140.1 - 7.9e-13 48.5 12.5 0.00011 21.7 0.1 4.8 1 1 2 4 4 4 4 MalT-like TPR region TPR_15 PF13429.6 KFP14140.1 - 3.5e-10 39.6 8.3 1.7e-05 24.2 0.5 4.9 1 1 2 5 5 5 2 Tetratricopeptide repeat FAT PF02259.23 KFP14140.1 - 5.9e-08 32.3 0.1 0.21 10.7 0.1 5.7 2 2 1 4 4 4 2 FAT domain MIT PF04212.18 KFP14140.1 - 2e-07 30.9 20.2 0.1 12.7 0.1 8.4 7 1 2 9 9 8 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KFP14140.1 - 2.7e-06 27.3 1.5 1.2 9.2 0.0 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFP14140.1 - 5.6e-06 26.2 11.0 0.17 11.6 0.0 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 KFP14140.1 - 7.7e-05 22.7 12.3 0.0083 16.1 0.2 4.6 5 0 0 5 5 4 1 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.6 KFP14140.1 - 0.00021 20.8 15.8 0.034 13.6 2.6 4.8 1 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP EST1_DNA_bind PF10373.9 KFP14140.1 - 0.00037 20.1 14.6 0.23 10.9 0.1 4.9 5 1 1 6 6 6 2 Est1 DNA/RNA binding domain SHNi-TPR PF10516.9 KFP14140.1 - 0.0015 18.0 2.5 12 5.4 0.0 5.6 7 0 0 7 7 6 0 SHNi-TPR BTAD PF03704.17 KFP14140.1 - 0.0028 18.1 16.0 0.33 11.4 1.4 5.7 3 2 4 7 7 7 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KFP14140.1 - 0.0053 17.0 16.7 0.027 14.7 1.3 5.5 3 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFP14140.1 - 0.027 14.7 5.2 1.8e+02 2.7 0.1 6.9 8 0 0 8 8 6 0 PPR repeat RPN7 PF10602.9 KFP14140.1 - 0.029 14.1 8.3 29 4.3 0.1 6.4 4 2 4 8 8 8 0 26S proteasome subunit RPN7 TOM20_plant PF06552.12 KFP14140.1 - 0.051 13.3 0.3 29 4.3 0.0 3.9 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Mad3_BUB1_I PF08311.12 KFP14140.1 - 0.064 13.2 8.5 91 3.1 0.1 6.8 6 1 1 8 8 8 0 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.6 KFP14140.1 - 0.068 13.2 0.5 1 9.5 0.0 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 KFP14140.1 - 0.098 12.7 3.6 5.2 7.1 0.0 4.6 3 1 2 5 5 4 0 Protein of unknown function (DUF627) Tcf25 PF04910.14 KFP14140.1 - 0.098 11.7 0.1 0.27 10.2 0.0 1.8 2 0 0 2 2 2 0 Transcriptional repressor TCF25 TPR_20 PF14561.6 KFP14140.1 - 0.27 11.6 13.4 1.9 8.9 0.2 6.0 4 2 4 9 9 9 0 Tetratricopeptide repeat DUF5113 PF17140.4 KFP14140.1 - 1 9.1 11.1 28 4.5 0.2 5.5 3 2 4 7 7 7 0 Domain of unknown function (DUF5113) Alkyl_sulf_dimr PF14863.6 KFP14140.1 - 4.2 7.8 5.6 13 6.2 0.3 3.3 4 0 0 4 4 2 0 Alkyl sulfatase dimerisation SprT-like PF10263.9 KFP14142.1 - 1.5e-07 31.2 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 SprT-like family DAAD PF18752.1 KFP14142.1 - 0.11 12.3 2.5 0.14 12.0 2.5 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase zf-C4 PF00105.18 KFP14143.1 - 9.9e-29 99.6 16.0 1.7e-28 98.9 16.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP14143.1 - 4.5e-24 85.2 1.0 2.6e-23 82.7 0.1 2.1 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 KFP14143.1 - 0.062 13.4 3.9 0.12 12.5 3.9 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type UPF0160 PF03690.13 KFP14144.1 - 3.4e-77 260.2 0.0 3.8e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ANAPC4_WD40 PF12894.7 KFP14145.1 - 1.1e-12 48.0 0.1 0.018 15.3 0.0 6.3 3 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP14145.1 - 2.8e-09 37.4 6.1 5e-05 24.0 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 KFP14145.1 - 1.4e-07 31.6 0.1 0.014 15.3 0.0 3.5 1 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFP14145.1 - 0.00034 20.5 0.3 0.38 10.7 0.1 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WDCP PF15390.6 KFP14145.1 - 0.00051 18.6 8.1 0.02 13.3 3.2 2.6 1 1 2 3 3 3 2 WD repeat and coiled-coil-containing protein family wnt PF00110.19 KFP14148.1 - 1.1e-124 416.0 23.7 1.3e-124 415.8 23.7 1.0 1 0 0 1 1 1 1 wnt family COG6 PF06419.11 KFP14148.1 - 0.28 9.4 0.1 0.38 8.9 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Hist_deacetyl PF00850.19 KFP14150.1 - 1.5e-51 175.7 0.0 2e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Phage_head_chap PF11113.8 KFP14150.1 - 0.18 11.9 0.3 0.49 10.5 0.3 1.8 1 1 0 1 1 1 0 Head assembly gene product Big_2 PF02368.18 KFP14152.1 - 7.7e-14 51.3 1.2 6.3e-12 45.2 0.0 6.9 9 0 0 9 9 9 2 Bacterial Ig-like domain (group 2) AlphaC_N PF08829.10 KFP14152.1 - 0.071 13.1 0.0 2.7 8.1 0.0 3.1 2 0 0 2 2 2 0 Alpha C protein N terminal PQQ PF01011.21 KFP14152.1 - 0.13 12.2 0.1 0.47 10.5 0.1 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat bZIP_2 PF07716.15 KFP14153.1 - 0.00087 19.3 2.8 0.0013 18.8 2.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper NRBF2 PF08961.10 KFP14153.1 - 0.0027 17.3 1.0 0.0029 17.2 1.0 1.0 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 KFP14153.1 - 0.0044 17.3 1.1 0.0047 17.2 1.1 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 KFP14153.1 - 0.014 15.5 2.5 0.014 15.4 2.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 KFP14153.1 - 0.02 14.6 1.9 0.022 14.5 1.9 1.1 1 0 0 1 1 1 0 Septum formation initiator Phage_Gp23 PF10669.9 KFP14153.1 - 0.03 14.7 0.2 0.032 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) ORF6C PF10552.9 KFP14153.1 - 0.04 14.0 0.7 0.04 14.0 0.7 1.0 1 0 0 1 1 1 0 ORF6C domain HSBP1 PF06825.12 KFP14153.1 - 0.042 13.7 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 BMFP PF04380.13 KFP14153.1 - 0.051 14.1 1.8 0.065 13.7 1.8 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity IQ_SEC7_PH PF16453.5 KFP14154.1 - 1.8e-67 225.6 2.1 4e-67 224.4 0.0 2.5 3 0 0 3 3 3 1 PH domain Sec7 PF01369.20 KFP14154.1 - 4e-63 212.4 0.1 8.9e-63 211.3 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain CCD48 PF15799.5 KFP14155.1 - 7e-46 156.7 11.5 7.7e-46 156.6 11.5 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 LRRNT PF01462.18 KFP14156.1 - 2.2e-07 30.3 3.3 2.2e-07 30.3 3.3 3.0 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 KFP14156.1 - 2.7e-05 23.8 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFP14156.1 - 0.0028 18.0 0.3 0.037 14.5 0.1 2.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRRCT PF01463.24 KFP14156.1 - 0.015 15.8 0.0 0.062 13.9 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain Ras PF00071.22 KFP14157.1 - 4.1e-36 124.0 0.1 5e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14157.1 - 9.3e-18 64.6 0.0 2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP14157.1 - 1.7e-06 27.6 0.1 2.1e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Hydrolase_6 PF13344.6 KFP14158.1 - 1e-11 44.8 0.0 2.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFP14158.1 - 5.3e-08 32.8 0.0 1.7e-06 28.0 0.0 2.9 1 1 0 1 1 1 1 HAD-hyrolase-like Isy1 PF06246.12 KFP14159.1 - 7.6e-68 228.8 7.1 8.8e-68 228.6 7.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Ebp2 PF05890.12 KFP14159.1 - 0.052 13.1 4.3 0.072 12.6 4.3 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 zf-CCHC PF00098.23 KFP14160.1 - 4.7e-53 175.0 63.9 3.3e-08 33.3 2.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KFP14160.1 - 3.8e-16 58.5 47.7 0.0004 20.0 1.7 7.1 5 1 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFP14160.1 - 7e-13 48.1 46.8 0.02 14.6 0.6 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KFP14160.1 - 1.7e-08 34.2 48.6 0.0024 17.8 0.3 7.0 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 KFP14160.1 - 0.0003 20.5 58.1 0.0037 17.0 1.4 7.2 7 0 0 7 7 7 5 Zinc knuckle Pkinase_Tyr PF07714.17 KFP14162.1 - 6.1e-63 212.5 0.0 8.2e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP14162.1 - 4e-61 206.7 0.0 5.4e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KFP14162.1 - 1.1e-27 95.8 0.1 2.5e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KFP14162.1 - 2.9e-12 46.3 8.5 5.6e-12 45.4 8.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP14162.1 - 4.6e-07 29.4 0.0 7.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP14162.1 - 8.2e-05 21.5 0.1 0.00014 20.8 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase zf-RING-like PF08746.11 KFP14162.1 - 0.00023 21.4 4.4 0.00077 19.7 4.4 1.9 1 0 0 1 1 1 1 RING-like domain C1_2 PF03107.16 KFP14162.1 - 0.036 14.4 4.0 0.073 13.4 4.0 1.5 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 KFP14162.1 - 0.45 10.7 3.6 2.1 8.5 3.6 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_2 PF13923.6 KFP14162.1 - 0.91 9.4 10.1 0.19 11.6 5.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP14162.1 - 6.4 7.2 12.5 0.46 10.9 7.2 1.9 2 0 0 2 2 2 0 Ring finger domain zf-CCCH_4 PF18044.1 KFP14163.1 - 1.4e-23 82.1 34.3 4.3e-07 29.6 3.7 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH PF00642.24 KFP14163.1 - 1.3e-20 72.8 29.6 1.3e-06 28.2 3.6 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP14163.1 - 4.9e-20 70.9 34.7 8.1e-06 25.7 8.3 5.4 4 1 0 4 4 4 4 Zinc finger domain Torus PF16131.5 KFP14163.1 - 2.4e-14 53.9 16.2 0.00026 21.7 0.9 4.5 3 1 1 4 4 4 4 Torus domain zf-CCCH_2 PF14608.6 KFP14163.1 - 1.9e-06 28.1 22.9 0.047 14.2 1.4 5.1 4 1 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP14163.1 - 2e-05 24.8 2.8 2e-05 24.8 2.8 3.0 3 0 0 3 3 3 1 Zinc-finger containing family zf-C3HC4 PF00097.25 KFP14163.1 - 8.8e-05 22.3 10.6 8.8e-05 22.3 10.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP14163.1 - 0.00036 20.5 6.4 0.00036 20.5 6.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP14163.1 - 0.00068 19.9 10.2 0.00068 19.9 10.2 3.8 4 1 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KFP14163.1 - 0.00097 19.1 9.1 0.00097 19.1 9.1 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP14163.1 - 0.0073 16.4 10.1 0.011 15.9 6.5 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING MKRN1_C PF15815.5 KFP14163.1 - 0.048 14.1 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-C3HC4_2 PF13923.6 KFP14163.1 - 0.96 9.3 17.7 0.5 10.2 10.8 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) tRNA_int_endo_N PF02778.14 KFP14164.1 - 1.2e-20 73.0 0.9 3.3e-14 52.3 0.6 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_endo PF01974.17 KFP14164.1 - 2.4e-17 62.7 0.0 5.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PPARgamma_N PF12577.8 KFP14166.1 - 6.8e-35 119.6 1.6 1.6e-34 118.3 1.6 1.7 1 0 0 1 1 1 1 PPAR gamma N-terminal region zf-C4 PF00105.18 KFP14166.1 - 1.5e-27 95.8 15.0 2.9e-27 94.9 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP14166.1 - 5.2e-17 62.1 0.4 1.4e-16 60.7 0.4 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Tmemb_55A PF09788.9 KFP14166.1 - 0.02 14.0 3.8 0.033 13.3 3.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A Synapsin_C PF02750.14 KFP14167.1 - 5.9e-134 444.0 0.9 7.2e-134 443.7 0.9 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 KFP14167.1 - 1.7e-11 44.3 0.1 9.4e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Synapsin, N-terminal domain TIMP PF00965.17 KFP14169.1 - 1.4e-58 197.7 3.9 1.5e-58 197.6 3.9 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.21 KFP14169.1 - 0.034 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module TLV_coat PF00429.19 KFP14171.1 - 0.0017 17.1 0.6 0.0018 17.1 0.6 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Tam41_Mmp37 PF09139.11 KFP14172.1 - 2.7e-87 293.2 0.0 3.2e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial VGLL4 PF15245.6 KFP14174.1 - 4e-106 353.9 5.2 3.6e-105 350.8 7.1 1.6 2 0 0 2 2 2 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.14 KFP14174.1 - 6.1e-05 22.7 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 2 Vestigial/Tondu family DUF3868 PF12984.7 KFP14174.1 - 0.04 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) 7tm_1 PF00001.21 KFP14175.1 - 1.9e-69 233.9 0.2 2.6e-69 233.5 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14175.1 - 2.5e-08 33.6 10.6 1.5e-05 24.6 6.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP14175.1 - 3.3e-07 30.3 12.4 2.5e-05 24.2 8.3 2.8 2 1 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP14175.1 - 5.5e-06 26.2 9.2 5.5e-06 26.2 9.2 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.13 KFP14175.1 - 0.0005 19.3 18.5 0.0019 17.4 2.0 2.8 2 1 0 2 2 2 2 Taste receptor protein (TAS2R) MAR_sialic_bdg PF10564.9 KFP14175.1 - 0.0053 16.8 0.3 0.011 15.7 0.3 1.6 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat Serpentine_r_xa PF03383.15 KFP14175.1 - 0.007 16.3 0.4 0.02 14.9 0.4 1.8 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa S_4TM PF18159.1 KFP14175.1 - 0.078 12.3 0.0 0.078 12.3 0.0 1.9 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain SUR7 PF06687.12 KFP14175.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.5 2 1 1 3 3 3 0 SUR7/PalI family SNF PF00209.18 KFP14176.1 - 8.1e-234 777.1 41.4 9.4e-234 776.9 41.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFP14177.1 - 3.8e-248 824.4 38.6 4.3e-248 824.2 38.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Cation_ATPase_C PF00689.21 KFP14180.1 - 8e-45 152.8 5.4 1.9e-44 151.5 2.6 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFP14180.1 - 8e-34 116.7 14.4 2.9e-25 88.9 1.5 2.9 3 0 0 3 3 3 2 E1-E2 ATPase ATP_Ca_trans_C PF12424.8 KFP14180.1 - 6.7e-27 93.7 0.1 1.9e-26 92.3 0.1 1.9 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Cation_ATPase PF13246.6 KFP14180.1 - 8.8e-18 64.2 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFP14180.1 - 2.7e-15 55.8 0.0 1.5e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFP14180.1 - 9.8e-15 55.4 0.1 1.9e-10 41.4 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP14180.1 - 1.1e-07 31.9 0.5 6.9e-06 26.0 0.2 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Orf78 PF06024.12 KFP14180.1 - 0.25 11.7 0.7 1.2 9.5 0.1 2.5 1 1 1 2 2 2 0 Orf78 (ac78) tRNA-synt_1 PF00133.22 KFP14184.1 - 4.5e-233 774.9 0.0 2.4e-232 772.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFP14184.1 - 4.5e-25 88.4 0.3 1.2e-24 87.0 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFP14184.1 - 2.4e-14 52.9 0.4 0.00033 19.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFP14184.1 - 0.0076 15.6 0.0 0.059 12.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain LRR_8 PF13855.6 KFP14186.1 - 2.8e-19 68.6 2.5 1.3e-07 31.3 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP14186.1 - 1.2e-12 47.8 7.9 0.00015 22.1 0.2 4.1 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP14186.1 - 1.4e-05 25.0 0.4 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP14186.1 - 3.6e-05 23.7 5.2 6.9 7.6 0.0 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP14186.1 - 0.00051 19.9 2.4 1.7 8.9 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 KFP14186.1 - 0.048 13.1 2.1 0.95 8.9 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeat DUF1374 PF07118.11 KFP14186.1 - 0.06 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) LRR_8 PF13855.6 KFP14187.1 - 1.2e-72 239.6 47.1 4.1e-13 48.9 0.8 9.3 7 2 2 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFP14187.1 - 8e-36 121.5 62.0 0.00053 20.3 0.2 12.2 4 3 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP14187.1 - 2.2e-21 76.1 9.5 1.5e-06 28.2 0.0 5.6 2 2 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP14187.1 - 1.1e-14 54.4 30.4 0.00034 20.1 0.4 6.0 3 2 3 6 6 6 5 Leucine-rich repeat LRRNT PF01462.18 KFP14187.1 - 2.9e-11 42.7 21.0 3.5e-07 29.7 3.0 5.9 6 0 0 6 6 6 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP14187.1 - 4.8e-05 23.3 47.1 1.6 9.5 0.1 15.4 14 4 1 15 15 15 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP14187.1 - 0.0045 16.9 43.9 7.1 7.0 0.2 13.2 16 0 0 16 16 16 3 Leucine Rich repeat LRR_8 PF13855.6 KFP14188.1 - 4.3e-50 167.3 20.8 2.2e-16 59.4 0.1 6.6 4 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP14188.1 - 6.3e-30 102.7 26.1 2.5e-05 24.5 1.5 8.7 5 1 3 9 9 9 8 Leucine Rich repeats (2 copies) VWC PF00093.18 KFP14188.1 - 2.8e-10 40.3 13.9 6.2e-10 39.2 13.9 1.6 1 0 0 1 1 1 1 von Willebrand factor type C domain LRR_1 PF00560.33 KFP14188.1 - 3.1e-10 39.1 27.3 10 7.1 0.2 12.0 9 2 1 10 10 10 2 Leucine Rich Repeat LRR_5 PF13306.6 KFP14188.1 - 5.2e-10 39.4 0.8 4.4e-05 23.4 0.0 3.5 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP14188.1 - 8.7e-09 35.1 13.6 5.8e-05 22.7 0.9 5.3 2 1 3 5 5 5 2 Leucine-rich repeat LRR_6 PF13516.6 KFP14188.1 - 8e-07 28.6 21.3 0.059 13.5 0.0 9.5 11 0 0 11 11 11 2 Leucine Rich repeat Amnionless PF14828.6 KFP14188.1 - 0.00023 20.1 7.1 0.00039 19.4 7.1 1.2 1 0 0 1 1 1 1 Amnionless FNIP PF05725.12 KFP14188.1 - 0.00061 19.9 4.6 16 5.8 0.0 4.8 3 1 1 4 4 4 1 FNIP Repeat LRRNT PF01462.18 KFP14188.1 - 0.54 10.0 10.6 0.59 9.9 0.2 3.8 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Ins_P5_2-kin PF06090.12 KFP14189.1 - 9.4e-92 308.0 0.6 1.1e-91 307.8 0.6 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C3HC4 PF00097.25 KFP14189.1 - 0.16 11.9 1.7 0.61 10.0 1.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTG PF07742.12 KFP14190.1 - 4e-28 97.6 0.0 6.5e-28 96.9 0.0 1.3 2 0 0 2 2 2 1 BTG family Shisa PF13908.6 KFP14191.1 - 1.2e-21 77.8 9.8 1.2e-21 77.8 9.8 1.9 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Prominin PF05478.11 KFP14191.1 - 3.3 5.5 8.7 3.8 5.4 8.7 1.0 1 0 0 1 1 1 0 Prominin Corona_S2 PF01601.16 KFP14191.1 - 3.6 6.0 6.4 4.2 5.7 6.4 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein EphA2_TM PF14575.6 KFP14191.1 - 9 7.3 6.5 33 5.4 6.5 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_9 PF14580.6 KFP14192.1 - 1.3e-16 60.6 1.3 1.8e-16 60.1 1.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP14192.1 - 1e-13 51.2 17.0 9.3e-08 32.3 2.9 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP14192.1 - 5.9e-08 32.4 21.0 4.7e-06 26.3 6.7 3.3 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFP14192.1 - 8.5e-06 25.4 6.7 0.095 12.8 0.2 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KFP14192.1 - 0.00021 21.4 9.2 0.79 10.5 0.3 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat SDA1 PF05285.12 KFP14192.1 - 0.47 9.8 30.8 0.59 9.5 30.8 1.3 1 0 0 1 1 1 0 SDA1 AMP-binding PF00501.28 KFP14193.1 - 1e-88 297.8 0.0 1.2e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme La PF05383.17 KFP14194.1 - 8.8e-21 73.7 0.8 1.4e-20 73.1 0.8 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFP14194.1 - 0.0054 16.5 0.0 1.8 8.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNR_N PF08343.10 KFP14194.1 - 0.092 12.8 0.1 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Dus PF01207.17 KFP14195.1 - 3.2e-57 194.0 0.0 4.3e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KFP14195.1 - 2.2e-05 24.1 11.8 3.3e-05 23.6 2.8 3.7 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP14195.1 - 0.0026 17.8 9.0 0.039 14.0 0.7 3.0 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KFP14195.1 - 0.0054 16.6 14.9 0.1 12.6 1.2 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FMN_dh PF01070.18 KFP14195.1 - 0.018 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PEP_mutase PF13714.6 KFP14195.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase CDC45 PF02724.14 KFP14195.1 - 0.89 7.8 2.5 1.2 7.3 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TGF_beta PF00019.20 KFP14196.1 - 6.9e-12 46.3 0.6 1.1e-11 45.6 0.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain BNIP2 PF12496.8 KFP14197.1 - 5.7e-42 143.4 0.3 1.1e-41 142.4 0.3 1.5 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFP14197.1 - 4.1e-28 98.3 0.2 5.4e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFP14197.1 - 1e-05 25.3 0.2 1.5e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain AAA_18 PF13238.6 KFP14198.1 - 0.0044 17.6 0.0 0.0076 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 KFP14199.1 - 4e-76 255.9 0.0 4.5e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14199.1 - 6.2e-37 127.3 0.0 7.3e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP14199.1 - 5.1e-06 26.0 0.2 1.1e-05 24.9 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP14199.1 - 9.8e-06 25.3 0.1 1.4e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFP14199.1 - 2.8e-05 23.1 0.0 4.2e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFP14199.1 - 0.037 13.6 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3847 PF12958.7 KFP14199.1 - 0.044 13.9 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) APH PF01636.23 KFP14199.1 - 0.049 13.6 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP14199.1 - 0.065 12.8 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glycos_trans_3N PF02885.17 KFP14199.1 - 0.1 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain GTP_EFTU PF00009.27 KFP14200.1 - 1.8e-64 216.9 0.0 2.4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFP14200.1 - 2.1e-33 114.7 0.0 8.7e-33 112.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFP14200.1 - 5.5e-23 80.8 0.0 1.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFP14200.1 - 2e-13 50.2 0.0 4.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFP14200.1 - 1.3e-11 44.7 0.1 7.9e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP14200.1 - 4.3e-05 23.6 0.1 8.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PINIT PF14324.6 KFP14201.1 - 1.2e-31 110.0 0.2 2.3e-31 109.1 0.2 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFP14201.1 - 6.9e-22 76.9 5.7 1.8e-21 75.6 5.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KFP14201.1 - 2.9e-05 23.7 0.1 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 KFP14201.1 - 4.9e-05 23.0 1.7 4.9e-05 23.0 1.7 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 KFP14201.1 - 0.31 11.7 2.2 1.9 9.1 2.5 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KFP14201.1 - 7 7.1 8.9 13 6.2 8.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 KFP14202.1 - 4.3e-61 206.6 0.0 6.1e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14202.1 - 2.8e-34 118.6 0.0 1.3e-32 113.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP14202.1 - 8.7e-05 21.5 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP14202.1 - 0.0038 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP14202.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP14202.1 - 0.015 15.3 0.0 0.028 14.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFP14202.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFP14202.1 - 0.2 11.0 0.5 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 KFP14203.1 - 1.5e-12 47.4 15.5 3e-12 46.5 15.2 1.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KFP14203.1 - 1.4e-08 34.7 10.3 1.4e-08 34.7 10.3 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KFP14203.1 - 4.3e-05 24.0 10.2 7.8e-05 23.1 10.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4407 PF14362.6 KFP14203.1 - 0.044 13.1 0.7 0.058 12.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KFP14203.1 - 0.059 13.4 11.7 0.091 12.9 11.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KFP14203.1 - 0.075 13.1 2.0 0.11 12.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KFP14203.1 - 0.15 12.5 9.5 0.043 14.2 6.2 1.8 1 1 1 2 2 2 0 Cell division protein ZapB RNA_polI_A14 PF08203.11 KFP14203.1 - 0.26 12.0 3.4 0.51 11.1 3.4 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF2009 PF09418.10 KFP14203.1 - 0.6 9.1 3.1 0.83 8.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) SOGA PF11365.8 KFP14203.1 - 0.69 11.1 10.1 0.57 11.3 0.6 1.8 1 1 1 2 2 2 0 Protein SOGA DUF724 PF05266.14 KFP14203.1 - 1.4 8.8 7.5 2.1 8.1 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFP14203.1 - 2.7 5.8 4.1 3.4 5.4 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SIR2 PF02146.17 KFP14204.1 - 3.9e-26 92.1 0.0 9.1e-18 64.8 0.0 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 KFP14204.1 - 0.00094 18.9 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain EGF_CA PF07645.15 KFP14205.1 - 0 1005.2 729.7 6.1e-11 42.3 5.1 49.2 48 1 2 50 50 50 44 Calcium-binding EGF domain cEGF PF12662.7 KFP14205.1 - 5.6e-198 640.0 411.6 3.9e-09 36.3 0.2 50.5 50 0 0 50 50 50 43 Complement Clr-like EGF-like TB PF00683.17 KFP14205.1 - 1.6e-117 383.0 156.2 9.7e-16 57.2 10.0 11.3 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFP14205.1 - 2.7e-103 337.7 670.7 0.00041 20.6 5.6 49.3 48 0 0 48 48 48 44 EGF-like domain FXa_inhibition PF14670.6 KFP14205.1 - 3.6e-85 279.9 717.0 2e-08 34.3 11.4 48.7 45 4 3 48 48 48 41 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFP14205.1 - 7.5e-68 223.1 666.8 0.00047 20.7 6.0 52.9 53 0 0 53 53 53 39 Human growth factor-like EGF EGF_3 PF12947.7 KFP14205.1 - 2.7e-36 123.5 616.7 2.7e-09 37.1 5.3 49.9 48 1 0 48 48 48 38 EGF domain Fibrillin_U_N PF18193.1 KFP14205.1 - 5.3e-25 87.2 7.7 5.3e-25 87.2 7.7 11.3 12 0 0 12 12 12 1 Fibrillin 1 unique N-terminal domain Cortexin PF11057.8 KFP14206.1 - 6.7e-40 134.8 0.1 7.6e-40 134.6 0.1 1.1 1 0 0 1 1 1 1 Cortexin of kidney Tim44 PF04280.15 KFP14207.1 - 5.7e-43 146.5 0.3 1.9e-42 144.8 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Kinase-PolyVal PF18762.1 KFP14207.1 - 0.032 14.2 0.2 0.067 13.1 0.2 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF5089 PF17002.5 KFP14207.1 - 0.15 11.9 17.1 1.3 8.8 15.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) DUF3347 PF11827.8 KFP14207.1 - 1.8 8.7 13.8 4.5 7.4 4.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) AIM3 PF17096.5 KFP14207.1 - 2.7 9.0 8.0 0.14 13.1 0.7 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RecG_N PF17190.4 KFP14207.1 - 6 7.7 8.8 9.3 7.1 4.2 3.1 2 1 1 3 3 3 0 RecG N-terminal helical domain PIN_8 PF18476.1 KFP14207.1 - 7.7 6.3 13.3 20 4.9 9.8 2.4 1 1 1 2 2 2 0 PIN like domain RRM_1 PF00076.22 KFP14208.1 - 3.7e-53 177.3 0.1 5.7e-19 67.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M PF11532.8 KFP14208.1 - 4.9e-18 65.0 8.7 1e-17 64.0 8.7 1.6 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Collagen_mid PF15984.5 KFP14208.1 - 2.1e-06 27.7 0.1 6.9e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 Bacterial collagen, middle region RRM_3 PF08777.11 KFP14208.1 - 3.9e-05 23.6 0.3 0.21 11.7 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFP14208.1 - 7e-05 22.8 0.2 0.0044 17.1 0.1 2.6 2 1 0 2 2 2 1 Limkain b1 RRM_5 PF13893.6 KFP14208.1 - 0.0024 17.5 0.0 0.15 11.6 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP14208.1 - 0.0087 15.9 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF3932 PF13068.6 KFP14208.1 - 0.046 14.0 0.0 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) DUF1664 PF07889.12 KFP14208.1 - 0.18 11.8 0.0 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF572 PF04502.13 KFP14209.1 - 1.5e-95 320.6 19.6 1.7e-95 320.5 19.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) BAR PF03114.18 KFP14210.1 - 2.3e-75 253.3 6.6 2.6e-75 253.1 6.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFP14210.1 - 1.2e-12 47.6 5.7 1.6e-10 40.6 2.7 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP14210.1 - 0.00018 21.3 5.8 0.00097 18.9 5.8 2.2 1 1 0 1 1 1 1 BAR domain of APPL family Prefoldin_3 PF13758.6 KFP14210.1 - 0.0023 18.0 3.2 0.065 13.3 2.2 2.3 2 0 0 2 2 2 1 Prefoldin subunit PhnG PF06754.12 KFP14210.1 - 0.11 12.4 1.3 0.38 10.7 0.8 2.1 1 1 0 1 1 1 0 Phosphonate metabolism protein PhnG DUF2570 PF10828.8 KFP14210.1 - 1.8 8.4 4.9 0.59 10.0 0.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) Noelin-1 PF12308.8 KFP14210.1 - 4.2 7.4 6.7 21 5.1 0.8 3.2 3 1 0 3 3 3 0 Neurogenesis glycoprotein Exonuc_VII_L PF02601.15 KFP14210.1 - 5.2 6.5 6.8 8 5.9 6.6 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit CAF1-p150_C2 PF15539.6 KFP14211.1 - 4e-120 400.6 2.0 1.9e-119 398.4 2.0 2.2 1 0 0 1 1 1 1 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.8 KFP14211.1 - 2.7e-65 219.0 69.3 8.1e-65 217.5 69.3 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1-p150_N PF15557.6 KFP14211.1 - 2.8e-30 106.0 7.8 2.8e-30 106.0 7.8 2.7 1 1 0 2 2 2 1 CAF1 complex subunit p150, region binding to PCNA CAF1A PF12253.8 KFP14211.1 - 4.6e-26 90.8 9.5 4.6e-26 90.8 9.5 5.1 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A Sema PF01403.19 KFP14212.1 - 3.5e-121 405.0 0.0 4.3e-121 404.7 0.0 1.0 1 0 0 1 1 1 1 Sema domain zf-U11-48K PF05253.12 KFP14212.1 - 0.23 11.4 1.9 0.42 10.6 0.3 2.2 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger DUF758 PF05527.11 KFP14213.1 - 6.5e-78 260.9 3.1 7.3e-78 260.7 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RPAP3_C PF13877.6 KFP14213.1 - 0.016 15.7 0.9 0.038 14.5 0.3 1.8 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Pico_P2B PF01552.17 KFP14213.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Picornavirus 2B protein DEP PF00610.21 KFP14213.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) UPF0556 PF10572.9 KFP14214.1 - 2.3e-82 274.0 0.0 2.6e-82 273.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 DPPIV_N PF00930.21 KFP14215.1 - 9e-103 343.7 0.0 1.2e-102 343.3 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP14215.1 - 7.4e-55 185.7 0.0 1.4e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFP14215.1 - 1.1e-06 28.5 0.1 2.2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFP14215.1 - 0.008 16.8 0.0 0.019 15.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFP14215.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KFP14215.1 - 0.04 13.5 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFP14215.1 - 0.047 13.3 0.9 0.75 9.4 0.1 2.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF4439 PF14530.6 KFP14215.1 - 0.1 13.3 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) Abhydrolase_2 PF02230.16 KFP14215.1 - 0.19 11.5 0.2 24 4.6 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Ank_2 PF12796.7 KFP14216.1 - 1.5e-44 150.4 0.6 1.2e-17 64.3 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFP14216.1 - 3.5e-35 118.9 10.2 9.7e-06 25.8 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 KFP14216.1 - 2.9e-33 113.8 2.5 1.7e-08 34.8 0.1 6.8 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP14216.1 - 2.7e-31 104.1 4.7 7.4e-05 22.9 0.0 9.3 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFP14216.1 - 1.1e-30 105.3 8.2 3.6e-07 30.3 0.1 7.3 3 1 4 7 7 7 7 Ankyrin repeats (many copies) TPR_12 PF13424.6 KFP14216.1 - 0.00085 19.6 0.1 0.06 13.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP14216.1 - 0.032 14.3 3.4 0.19 11.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP14216.1 - 0.096 12.6 2.5 0.46 10.4 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_Tnp_IS91 PF14319.6 KFP14216.1 - 0.86 9.7 8.1 0.44 10.6 5.5 1.8 2 0 0 2 2 2 0 Transposase zinc-binding domain TRIF-NTD PF17798.1 KFP14217.1 - 6e-55 185.6 3.1 9.4e-55 185.0 3.1 1.3 1 0 0 1 1 1 1 TRIF N-terminal domain TIR_2 PF13676.6 KFP14217.1 - 0.00091 19.8 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR-like PF10137.9 KFP14217.1 - 0.041 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Coleoptericin PF06286.11 KFP14217.1 - 2.5 8.2 4.1 15 5.7 0.4 2.9 3 1 0 3 3 3 0 Coleoptericin Perilipin PF03036.16 KFP14218.1 - 1.1e-143 479.1 18.1 1.2e-143 478.9 18.1 1.0 1 0 0 1 1 1 1 Perilipin family ISG65-75 PF11727.8 KFP14218.1 - 0.0047 16.2 1.7 1.5 8.0 0.1 3.2 3 0 0 3 3 3 1 Invariant surface glycoprotein MAP65_ASE1 PF03999.12 KFP14218.1 - 0.014 14.2 7.0 0.29 9.8 4.7 2.5 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) PHA_gran_rgn PF09650.10 KFP14218.1 - 0.022 15.1 0.3 0.1 12.9 0.3 2.2 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) CRIC_ras_sig PF10534.9 KFP14218.1 - 0.088 13.0 2.4 14 6.0 0.2 2.8 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF883 PF05957.13 KFP14218.1 - 0.2 12.3 10.8 0.12 13.0 2.6 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) UPF0444 PF15475.6 KFP14218.1 - 0.28 11.5 5.9 0.29 11.4 1.5 2.5 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Sec5 PF15469.6 KFP14218.1 - 0.76 9.6 5.2 0.41 10.4 2.4 2.1 2 1 0 2 2 2 0 Exocyst complex component Sec5 TTD PF12148.8 KFP14219.1 - 1.5e-66 223.1 0.5 2.5e-66 222.3 0.5 1.4 1 0 0 1 1 1 1 Tandem tudor domain within UHRF1 SAD_SRA PF02182.17 KFP14219.1 - 1e-56 191.0 0.1 2.5e-56 189.7 0.1 1.7 1 0 0 1 1 1 1 SAD/SRA domain PHD PF00628.29 KFP14219.1 - 3.5e-12 46.0 7.6 3.5e-12 46.0 7.6 3.6 3 1 1 4 4 3 1 PHD-finger zf-C3HC4_2 PF13923.6 KFP14219.1 - 0.00045 20.0 12.1 0.00045 20.0 12.1 3.1 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP14219.1 - 0.00086 19.1 8.7 0.00086 19.1 8.7 3.4 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP14219.1 - 0.0011 18.7 12.3 0.0011 18.7 12.3 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KFP14219.1 - 0.0011 18.4 0.5 0.0011 18.4 0.5 2.9 3 0 0 3 3 2 1 PHD-finger zf-RING_10 PF16685.5 KFP14219.1 - 0.0091 16.1 7.4 0.0091 16.1 7.4 3.0 2 1 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 KFP14219.1 - 0.012 15.6 9.1 0.012 15.6 9.1 2.3 2 0 0 2 2 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFP14219.1 - 0.014 15.7 12.2 0.014 15.7 12.2 3.1 2 1 1 3 3 3 0 Ring finger domain Agenet PF05641.12 KFP14219.1 - 0.028 14.9 0.1 11 6.6 0.1 2.9 2 1 0 2 2 2 0 Agenet domain Tudor-knot PF11717.8 KFP14219.1 - 0.038 13.9 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF3592 PF12158.8 KFP14219.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) JmjC PF02373.22 KFP14220.1 - 2.9e-44 150.1 0.3 7.9e-44 148.7 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFP14220.1 - 5.3e-36 123.1 9.0 5.3e-36 123.1 9.0 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_2 PF18104.1 KFP14220.1 - 8.1e-32 108.6 1.4 1.4e-16 59.9 0.4 2.6 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain zf-HC5HC2H PF13771.6 KFP14220.1 - 3.8e-18 65.5 5.5 3.8e-18 65.5 5.5 3.2 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP14220.1 - 1.6e-13 49.9 15.7 2.1e-13 49.6 6.9 2.9 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 KFP14220.1 - 2.8e-13 49.6 0.0 8.6e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 jmjN domain LBR_tudor PF09465.10 KFP14220.1 - 6.9e-06 25.8 0.7 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain PHD PF00628.29 KFP14220.1 - 9.7e-06 25.4 22.2 4.8e-05 23.2 2.7 3.2 3 0 0 3 3 3 2 PHD-finger Tudor_3 PF18115.1 KFP14220.1 - 0.0087 15.9 0.5 1.1 9.1 0.2 2.5 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KFP14220.1 - 0.018 15.1 0.1 0.14 12.2 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.10 KFP14220.1 - 0.028 14.6 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding SLX9 PF15341.6 KFP14220.1 - 1.5 9.2 8.9 3.6 8.0 8.9 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Y_phosphatase PF00102.27 KFP14221.1 - 7.4e-168 555.9 0.3 1.5e-84 283.2 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP14221.1 - 1.7e-111 364.8 24.4 6.6e-17 61.6 0.1 9.7 9 1 0 9 9 9 8 Fibronectin type III domain I-set PF07679.16 KFP14221.1 - 2.4e-41 139.7 0.0 2.6e-16 59.5 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP14221.1 - 1.4e-37 128.1 4.8 1.8e-11 44.5 0.0 6.1 6 0 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 KFP14221.1 - 3e-25 88.4 0.1 2.8e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 KFP14221.1 - 7.8e-18 64.4 0.0 5.3e-05 23.3 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP14221.1 - 3.2e-16 59.7 16.4 0.14 12.8 0.0 9.6 8 2 0 8 8 8 5 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFP14221.1 - 8.9e-14 51.4 0.0 0.0013 18.8 0.0 7.8 8 0 0 8 8 8 2 Fibronectin type III domain Interfer-bind PF09294.10 KFP14221.1 - 2e-11 44.1 0.0 0.36 11.2 0.0 6.4 7 0 0 7 7 5 2 Interferon-alpha/beta receptor, fibronectin type III DSPc PF00782.20 KFP14221.1 - 6.8e-09 35.6 0.0 0.0045 16.8 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP14221.1 - 6.5e-07 29.6 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family C2-set_2 PF08205.12 KFP14221.1 - 6.4e-06 26.1 0.4 0.35 11.0 0.0 4.0 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP14221.1 - 8e-06 26.0 1.5 4.6 7.5 0.0 6.5 5 2 0 5 5 5 1 Immunoglobulin V-set domain PTPlike_phytase PF14566.6 KFP14221.1 - 1.4e-05 25.2 0.0 0.0098 16.0 0.0 3.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Ig_5 PF16681.5 KFP14221.1 - 0.00046 20.5 0.0 0.61 10.5 0.0 3.7 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF2369 PF10179.9 KFP14221.1 - 0.0026 18.1 0.0 79 3.7 0.0 5.9 7 0 0 7 7 6 0 Uncharacterised conserved protein (DUF2369) fn3_4 PF16794.5 KFP14221.1 - 0.025 14.5 4.2 7.4 6.5 0.0 5.6 7 0 0 7 7 7 0 Fibronectin-III type domain DUF4998 PF16389.5 KFP14221.1 - 0.042 13.4 0.1 1.1 8.8 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function Glyco_hydro_36C PF16874.5 KFP14221.1 - 0.1 13.1 0.0 1.7e+02 2.8 0.0 4.7 4 0 0 4 4 4 0 Glycosyl hydrolase family 36 C-terminal domain Ig_C17orf99 PF17736.1 KFP14221.1 - 0.11 12.5 0.0 16 5.6 0.0 3.9 3 1 0 3 3 3 0 C17orf99 Ig domain Tropomyosin PF00261.20 KFP14222.1 - 1.1e-102 342.4 85.1 1.9e-97 325.3 61.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP14222.1 - 1e-39 135.9 71.9 1.1e-35 122.9 40.1 3.1 1 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFP14222.1 - 6.1e-08 32.8 32.4 0.00026 21.0 7.4 3.3 1 1 2 3 3 3 2 Laminin Domain II CLZ PF16526.5 KFP14222.1 - 2.9e-07 30.7 46.9 4.3e-06 27.0 8.7 5.1 2 2 3 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_I PF06008.14 KFP14222.1 - 2.7e-05 24.0 49.8 0.00011 22.0 13.7 3.2 1 1 2 3 3 3 2 Laminin Domain I ATG16 PF08614.11 KFP14222.1 - 0.00029 21.1 56.8 0.0041 17.4 18.6 3.5 1 1 1 2 2 1 1 Autophagy protein 16 (ATG16) ERM PF00769.19 KFP14222.1 - 0.0021 17.9 68.2 0.28 11.0 23.3 2.7 1 1 1 2 2 2 2 Ezrin/radixin/moesin family BST2 PF16716.5 KFP14222.1 - 0.0022 18.5 7.7 0.0022 18.5 7.7 5.0 1 1 4 5 5 5 1 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 KFP14222.1 - 0.005 16.8 14.2 0.005 16.8 14.2 6.4 1 1 4 6 6 5 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KFP14222.1 - 0.0053 16.8 65.2 0.016 15.2 30.9 2.5 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KFP14222.1 - 0.0072 15.7 8.3 0.0072 15.7 8.3 3.7 1 1 3 4 4 4 1 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KFP14222.1 - 0.0078 14.9 46.5 0.21 10.2 26.2 2.0 1 1 1 2 2 2 2 AAA domain DHR10 PF18595.1 KFP14222.1 - 0.015 15.4 28.3 0.015 15.4 28.3 3.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain XhlA PF10779.9 KFP14222.1 - 0.019 15.2 2.6 0.019 15.2 2.6 6.5 1 1 6 7 7 7 0 Haemolysin XhlA Lebercilin PF15619.6 KFP14222.1 - 0.027 14.1 58.9 0.12 12.0 16.8 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MscS_porin PF12795.7 KFP14222.1 - 0.029 13.9 43.2 0.092 12.3 20.0 3.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain COG2 PF06148.11 KFP14222.1 - 0.048 13.8 1.4 0.048 13.8 1.4 4.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFP14222.1 - 0.073 13.1 31.4 0.079 13.0 4.1 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SNARE PF05739.19 KFP14222.1 - 0.091 12.8 5.9 2.3 8.3 0.1 3.9 3 1 1 4 4 4 0 SNARE domain HrpB7 PF09486.10 KFP14222.1 - 0.094 13.1 50.1 0.046 14.1 13.3 4.4 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF745 PF05335.13 KFP14222.1 - 0.17 11.6 46.4 0.86 9.3 7.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Spc7 PF08317.11 KFP14222.1 - 0.22 10.4 62.6 0.12 11.2 26.9 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 KFP14222.1 - 0.23 12.1 45.1 0.21 12.2 1.2 5.6 1 1 4 5 5 5 0 SlyX FPP PF05911.11 KFP14222.1 - 0.27 9.4 60.1 0.046 11.9 30.6 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KFP14222.1 - 0.3 10.5 53.5 4 6.8 21.5 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 EzrA PF06160.12 KFP14222.1 - 0.31 9.2 54.6 0.24 9.5 6.4 3.2 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 KFP14222.1 - 0.38 10.3 32.9 3.7 7.0 16.8 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KFP14222.1 - 0.47 7.9 54.4 0.41 8.1 23.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 KFP14222.1 - 0.48 10.9 19.3 3.2 8.3 2.3 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KFP14222.1 - 0.8 10.2 39.0 0.54 10.8 6.5 4.4 1 1 3 4 4 4 0 Protein of unknown function DUF16 ADIP PF11559.8 KFP14222.1 - 0.87 9.7 48.3 1.5 8.9 6.9 4.2 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KFP14222.1 - 0.92 9.9 51.1 11 6.4 25.0 3.1 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 KFP14222.1 - 1.3 9.2 30.8 0.25 11.5 6.5 3.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 KFP14222.1 - 1.8 7.6 38.7 0.18 10.9 8.8 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain GAS PF13851.6 KFP14222.1 - 2 7.7 63.5 0.52 9.6 23.3 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Flagellin_N PF00669.20 KFP14222.1 - 2.1 8.5 17.7 2 8.5 5.6 3.8 1 1 3 4 4 4 0 Bacterial flagellin N-terminal helical region FUSC PF04632.12 KFP14222.1 - 2.6 6.5 16.5 4.2 5.8 9.6 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family Uds1 PF15456.6 KFP14222.1 - 2.7 8.2 48.0 0.89 9.7 15.2 5.2 1 1 4 5 5 5 0 Up-regulated During Septation DUF1794 PF08768.11 KFP14222.1 - 2.8 7.9 5.1 28 4.6 0.2 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1794) HemX PF04375.14 KFP14222.1 - 3.1 7.0 35.6 1.1 8.4 13.4 3.2 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase LOH1CR12 PF10158.9 KFP14222.1 - 4.8 7.2 14.3 0.86 9.6 2.2 3.3 1 1 1 3 3 3 0 Tumour suppressor protein T3SSipB PF16535.5 KFP14222.1 - 5.2 7.5 48.1 1.2 9.6 14.2 4.5 1 1 3 4 4 4 0 Type III cell invasion protein SipB DUF2721 PF11026.8 KFP14222.1 - 7.1 6.5 6.3 9.2 6.2 0.2 3.1 2 1 2 4 4 2 0 Protein of unknown function (DUF2721) TTKRSYEDQ PF10212.9 KFP14222.1 - 7.5 5.4 35.5 2.1 7.3 10.8 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ApoO PF09769.9 KFP14222.1 - 7.9 6.5 9.2 8.8 6.3 0.4 3.8 1 1 1 3 3 3 0 Apolipoprotein O SH3BP5 PF05276.14 KFP14222.1 - 8.2 6.2 44.6 1.1 9.0 8.9 4.0 1 1 2 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Ras PF00071.22 KFP14223.1 - 4.9e-51 172.5 0.2 6.3e-51 172.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14223.1 - 2.9e-21 75.9 0.2 5.8e-21 74.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP14223.1 - 2.6e-10 40.0 0.2 3.2e-10 39.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP14223.1 - 0.0012 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP14223.1 - 0.0059 16.0 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3963 PF13124.6 KFP14223.1 - 0.054 13.5 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) EF-hand_7 PF13499.6 KFP14224.1 - 1.8e-15 57.1 3.9 2.5e-12 47.0 0.7 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP14224.1 - 5.7e-12 44.3 6.4 5.7e-05 22.4 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP14224.1 - 4.4e-11 41.8 6.0 0.0015 18.3 0.3 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP14224.1 - 5.9e-05 22.8 4.3 0.0081 16.0 0.4 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP14224.1 - 0.0035 16.8 0.1 0.0035 16.8 0.1 3.3 4 0 0 4 4 4 1 EF hand EF-hand_13 PF17958.1 KFP14224.1 - 0.046 13.5 0.0 16 5.4 0.0 3.2 2 1 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KFP14224.1 - 0.047 14.0 0.4 0.1 13.0 0.4 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP14224.1 - 0.091 13.0 3.1 0.13 12.5 0.7 2.2 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_4 PF12763.7 KFP14224.1 - 0.35 10.8 1.5 0.47 10.4 0.3 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand AAA_10 PF12846.7 KFP14225.1 - 0.0038 16.2 2.7 0.0042 16.1 2.7 1.0 1 0 0 1 1 1 1 AAA-like domain UPF0172 PF03665.13 KFP14225.1 - 0.027 14.5 1.0 0.031 14.3 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF5384 PF17358.2 KFP14225.1 - 0.44 10.6 11.3 0.49 10.4 11.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5384) DUF1754 PF08555.10 KFP14225.1 - 0.6 10.9 19.3 0.56 11.0 15.4 2.5 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF3395 PF11875.8 KFP14225.1 - 4.4 7.2 11.4 0.31 10.9 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DUF1764 PF08576.10 KFP14225.1 - 8.1 7.4 9.9 10 7.1 9.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) zf-C2H2 PF00096.26 KFP14226.1 - 6.8e-13 48.3 25.8 9.4e-06 25.8 4.2 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP14226.1 - 3.9e-09 36.5 15.3 5e-07 29.9 4.3 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP14226.1 - 7.6e-07 29.5 19.2 0.0049 17.6 3.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP14226.1 - 0.028 14.7 4.1 2 8.8 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFP14226.1 - 0.12 12.8 4.4 11 6.5 0.1 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFP14226.1 - 0.33 11.4 9.5 2.5 8.6 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type EF-hand_4 PF12763.7 KFP14227.1 - 1.7e-42 143.6 0.0 1.2e-22 79.8 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFP14227.1 - 1.6e-12 46.0 2.9 0.0026 17.2 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP14227.1 - 9.1e-10 37.7 0.8 0.051 13.5 0.2 5.0 5 0 0 5 5 4 2 EF-hand domain EF-hand_7 PF13499.6 KFP14227.1 - 8.3e-07 29.4 0.5 0.11 12.9 0.1 4.1 3 0 0 3 3 3 2 EF-hand domain pair Macoilin PF09726.9 KFP14227.1 - 1.7e-05 23.7 16.8 2.4e-05 23.1 16.8 1.2 1 0 0 1 1 1 1 Macoilin family BicD PF09730.9 KFP14227.1 - 0.0001 20.9 28.4 0.00015 20.3 28.4 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D EzrA PF06160.12 KFP14227.1 - 0.00055 18.3 40.4 0.0019 16.4 40.5 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA EF-hand_5 PF13202.6 KFP14227.1 - 0.0008 18.8 3.5 0.38 10.3 0.1 2.7 2 0 0 2 2 2 2 EF hand DUF4201 PF13870.6 KFP14227.1 - 0.00083 19.1 15.6 0.00083 19.1 15.6 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) EF-hand_8 PF13833.6 KFP14227.1 - 0.00091 19.0 1.8 0.16 11.9 0.2 3.6 4 0 0 4 4 4 1 EF-hand domain pair CALCOCO1 PF07888.11 KFP14227.1 - 0.0012 17.8 34.4 0.0022 16.9 34.4 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin PF00261.20 KFP14227.1 - 0.0028 17.1 20.5 0.0028 17.1 20.5 2.6 2 1 1 3 3 2 1 Tropomyosin Spc7 PF08317.11 KFP14227.1 - 0.0036 16.2 47.1 0.028 13.3 23.5 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein EF-hand_9 PF14658.6 KFP14227.1 - 0.0051 17.1 0.4 0.38 11.1 0.0 3.5 4 0 0 4 4 2 1 EF-hand domain Atg14 PF10186.9 KFP14227.1 - 0.028 13.5 41.1 0.49 9.4 11.8 3.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 KFP14227.1 - 0.049 13.1 46.4 0.12 11.8 17.5 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4763 PF15960.5 KFP14227.1 - 0.1 11.9 41.6 0.021 14.1 9.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 KFP14227.1 - 0.14 12.2 30.9 0.022 14.8 5.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KFP14227.1 - 0.19 9.6 24.1 0.31 9.0 24.1 1.2 1 0 0 1 1 1 0 Prominin DUF745 PF05335.13 KFP14227.1 - 0.27 10.9 34.0 2.3 7.9 19.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ATG16 PF08614.11 KFP14227.1 - 0.42 10.8 55.4 0.3 11.3 31.8 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 KFP14227.1 - 0.55 9.1 21.0 0.86 8.4 21.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 KFP14227.1 - 0.57 9.4 34.5 1.1 8.4 15.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein AAA_13 PF13166.6 KFP14227.1 - 0.62 8.6 33.6 5.7 5.5 33.6 2.0 1 1 0 1 1 1 0 AAA domain IFT57 PF10498.9 KFP14227.1 - 0.71 8.8 38.1 2 7.3 35.5 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FUSC PF04632.12 KFP14227.1 - 1.1 7.7 6.8 1.7 7.0 6.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 KFP14227.1 - 1.3 9.3 20.5 3.4 8.0 0.5 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) MAD PF05557.13 KFP14227.1 - 1.6 7.0 45.9 4.7 5.5 45.9 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Fez1 PF06818.15 KFP14227.1 - 1.8 9.0 48.2 0.47 10.9 31.0 2.7 2 1 1 3 3 3 0 Fez1 DUF3584 PF12128.8 KFP14227.1 - 2.2 5.7 38.7 0.033 11.7 31.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) zf-C4H2 PF10146.9 KFP14227.1 - 3.4 7.9 37.6 0.035 14.4 12.7 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein Med30 PF11315.8 KFP14227.1 - 3.5 7.8 29.1 1.9 8.7 24.5 2.7 1 1 2 3 3 3 0 Mediator complex subunit 30 APG6_N PF17675.1 KFP14227.1 - 3.9 8.0 61.7 0.34 11.4 29.5 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 KFP14227.1 - 4.1 6.7 45.6 2.6 7.4 18.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CREPT PF16566.5 KFP14227.1 - 4.6 7.4 32.2 7.2 6.8 0.3 3.4 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Filament PF00038.21 KFP14227.1 - 5.8 6.4 42.8 1.3 8.5 11.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein Laminin_II PF06009.12 KFP14227.1 - 6.6 6.7 33.8 2.4 8.2 1.9 3.2 1 1 2 3 3 3 0 Laminin Domain II DUF812 PF05667.11 KFP14227.1 - 9.6 5.0 43.5 38 3.0 19.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Calreticulin PF00262.18 KFP14228.1 - 8e-81 271.7 12.1 7.4e-60 202.7 2.0 2.1 1 1 1 2 2 2 2 Calreticulin family MDM10 PF12519.8 KFP14228.1 - 0.0019 17.2 1.1 0.0025 16.8 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 IATP PF04568.12 KFP14228.1 - 0.17 12.3 3.1 0.34 11.4 3.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4614 PF15391.6 KFP14229.1 - 1.3e-21 77.5 0.3 1.4e-21 77.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) CTD_bind PF04818.13 KFP14230.1 - 3.7e-18 66.1 2.5 4.3e-18 65.9 0.6 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. G-patch PF01585.23 KFP14230.1 - 1.8e-11 43.7 4.6 4e-11 42.6 4.6 1.6 1 0 0 1 1 1 1 G-patch domain Apt1 PF10351.9 KFP14230.1 - 0.11 11.3 13.7 0.18 10.7 13.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPT PF03151.16 KFP14231.1 - 1.3e-68 231.5 15.7 1.5e-68 231.3 15.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP14231.1 - 4e-13 49.7 20.8 1.5e-09 38.1 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFP14231.1 - 0.00011 21.5 16.2 0.00014 21.2 16.2 1.1 1 0 0 1 1 1 1 UAA transporter family YwiC PF14256.6 KFP14231.1 - 0.48 10.8 5.5 0.18 12.1 0.4 2.2 1 1 1 2 2 2 0 YwiC-like protein Med26_C PF15693.5 KFP14232.1 - 3.7e-92 307.5 1.5 4.2e-92 307.3 1.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit 26 C-terminal Pullulanase_N2 PF17967.1 KFP14232.1 - 0.014 16.2 0.0 0.021 15.7 0.0 1.3 1 0 0 1 1 1 0 Pullulanase N2 domain UBD PF16455.5 KFP14232.1 - 0.052 13.8 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding domain SLY PF12485.8 KFP14232.1 - 0.085 13.6 1.3 0.12 13.1 1.3 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Sin3a_C PF16879.5 KFP14233.1 - 4.7e-86 289.0 6.3 4.7e-86 289.0 6.3 2.4 2 1 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KFP14233.1 - 5.1e-42 141.9 0.2 5.1e-42 141.9 0.2 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 KFP14233.1 - 9.5e-42 140.9 9.1 4.7e-17 61.9 0.4 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat 7tm_1 PF00001.21 KFP14234.1 - 9.4e-46 156.3 20.8 2e-45 155.2 20.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP14234.1 - 7.1e-09 35.8 13.4 1.9e-08 34.4 13.4 1.6 1 1 0 1 1 1 1 Olfactory receptor TED_complement PF07678.14 KFP14235.1 - 1.5e-106 356.0 0.3 2.7e-106 355.1 0.3 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 KFP14235.1 - 1e-39 136.1 1.5 2.7e-37 128.2 0.1 4.3 3 1 0 3 3 3 1 Alpha-2-macroglobulin bait region domain Methyltransf_FA PF12248.8 KFP14235.1 - 5.1e-34 116.6 0.5 1.6e-33 115.1 0.5 1.9 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase A2M PF00207.22 KFP14235.1 - 1.3e-30 105.0 3.1 9.9e-30 102.2 0.1 3.7 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_recep PF07677.14 KFP14235.1 - 1.1e-26 93.3 0.0 3.3e-26 91.8 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG4 PF17789.1 KFP14235.1 - 5.9e-12 45.6 1.3 5e-11 42.6 0.0 3.2 3 0 0 3 3 3 1 Macroglobulin domain MG4 MG2 PF01835.19 KFP14235.1 - 3e-11 43.6 0.0 1.5e-10 41.4 0.0 2.3 2 0 0 2 2 2 1 MG2 domain MG3 PF17791.1 KFP14235.1 - 7.4e-11 42.2 0.0 2.5e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG3 Kazal_2 PF07648.15 KFP14235.1 - 4e-07 30.1 6.2 1.3e-06 28.4 6.2 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain MG1 PF17790.1 KFP14235.1 - 0.0002 21.7 0.0 0.0013 19.1 0.0 2.5 1 0 0 1 1 1 1 Macroglobulin domain MG1 Kazal_1 PF00050.21 KFP14235.1 - 0.0022 17.9 6.9 0.0068 16.4 6.9 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Rib PF08428.10 KFP14235.1 - 0.0025 17.8 0.5 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 Rib/alpha-like repeat DLP_helical PF18709.1 KFP14236.1 - 0.011 15.0 0.3 0.011 15.0 0.3 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain QWRF PF04484.12 KFP14236.1 - 0.031 14.0 4.4 0.039 13.7 4.4 1.1 1 0 0 1 1 1 0 QWRF family Pkinase_Tyr PF07714.17 KFP14237.1 - 1.5e-95 319.4 0.0 3.5e-95 318.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFP14237.1 - 1.7e-57 192.4 1.7 1e-28 99.7 0.1 2.4 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KFP14237.1 - 4.2e-40 137.8 0.0 7.4e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFP14237.1 - 3.7e-37 127.5 43.5 1e-36 126.1 43.5 1.8 1 0 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.21 KFP14237.1 - 3.6e-21 75.3 2.0 2.3e-07 31.0 0.1 5.0 4 1 0 4 4 4 4 Fibronectin type III domain Insulin_TMD PF17870.1 KFP14237.1 - 6.1e-21 74.2 2.8 1.2e-20 73.3 2.8 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Kinase-like PF14531.6 KFP14237.1 - 0.00075 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like B2 PF11473.8 KFP14237.1 - 0.092 12.6 0.0 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 RNA binding protein B2 Toxin_29 PF08116.11 KFP14237.1 - 4.4 7.4 17.1 0.12 12.4 9.8 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family PH_16 PF17838.1 KFP14238.1 - 2.6e-41 140.4 0.1 5.7e-41 139.3 0.1 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFP14238.1 - 2.4e-33 115.9 4.0 2.4e-33 115.9 4.0 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP14238.1 - 4.7e-07 30.3 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF5082 PF16888.5 KFP14238.1 - 0.00016 21.9 2.8 0.00016 21.9 2.8 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF5082) PH_13 PF16652.5 KFP14238.1 - 0.00046 20.0 0.3 0.00046 20.0 0.3 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain DUF572 PF04502.13 KFP14238.1 - 0.43 10.1 18.0 1.4 8.5 18.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF572) Kelch_1 PF01344.25 KFP14239.1 - 5.5e-49 163.5 9.3 4e-12 45.5 0.7 5.5 5 0 0 5 5 5 5 Kelch motif BACK PF07707.15 KFP14239.1 - 1.8e-30 105.0 2.0 2.6e-30 104.6 1.2 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP14239.1 - 4.9e-25 86.9 6.7 6.7e-06 26.2 0.4 5.5 1 1 4 5 5 5 5 Kelch motif BTB PF00651.31 KFP14239.1 - 1.1e-24 86.7 0.1 2e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KFP14239.1 - 5.1e-23 80.8 2.6 5.1e-06 26.6 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP14239.1 - 4.2e-20 71.5 0.2 1.6e-06 28.0 0.0 5.4 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP14239.1 - 1.5e-19 69.1 5.0 8.1e-05 22.4 0.2 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KFP14239.1 - 9.8e-13 47.8 6.4 3.7e-05 23.6 0.0 6.4 7 0 0 7 7 7 2 Kelch motif DUF3342 PF11822.8 KFP14239.1 - 0.0015 18.7 0.0 0.0047 17.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFP14239.1 - 0.12 12.9 5.8 0.65 10.6 0.0 3.5 5 0 0 5 5 3 0 PQQ-like domain HTH_12 PF08461.10 KFP14239.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain RRM_1 PF00076.22 KFP14240.1 - 3.1e-13 49.3 0.0 8.7e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP14240.1 - 2.6e-07 30.2 0.0 5.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 KFP14242.1 - 8.2e-30 103.7 0.1 8.5e-29 100.4 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP14242.1 - 4.7e-16 59.1 0.1 5.4e-15 55.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP14242.1 - 0.00041 20.3 0.1 0.42 10.5 0.1 2.2 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 KFP14242.1 - 0.00058 19.3 0.0 0.00079 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) SE PF08491.10 KFP14242.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase RRM_1 PF00076.22 KFP14243.1 - 7e-38 128.3 0.0 3.4e-17 62.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP14243.1 - 0.0067 16.4 0.0 1.5 8.8 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP14243.1 - 0.077 13.2 0.2 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM PF05172.13 KFP14243.1 - 0.19 11.7 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NOP5NT PF08156.13 KFP14243.1 - 0.22 11.9 0.5 52 4.3 0.1 3.1 3 0 0 3 3 3 0 NOP5NT (NUC127) domain Peptidase_M28 PF04389.17 KFP14244.1 - 8.7e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 KFP14244.1 - 1.1e-06 28.2 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Trypsin PF00089.26 KFP14245.1 - 1.3e-58 198.5 0.1 1.5e-58 198.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP14245.1 - 3.4e-05 24.8 0.0 7.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP14245.1 - 0.041 14.3 0.0 0.31 11.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 KFP14246.1 - 2e-27 96.4 0.1 9.2e-20 71.4 0.0 2.0 1 1 1 2 2 2 2 Trypsin DUF1986 PF09342.11 KFP14246.1 - 0.02 15.3 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) G-alpha PF00503.20 KFP14247.1 - 1.1e-108 363.6 1.8 1.2e-108 363.5 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP14247.1 - 5.4e-12 45.5 0.6 2.7e-11 43.2 0.2 2.2 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP14247.1 - 0.11 12.6 0.1 1.6 8.8 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase TLE_N PF03920.15 KFP14248.1 - 2.2e-50 170.1 6.5 2.8e-50 169.8 6.5 1.1 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain FliG_N PF14842.6 KFP14248.1 - 0.011 16.3 0.3 0.017 15.7 0.3 1.4 1 0 0 1 1 1 0 FliG N-terminal domain TLE_N PF03920.15 KFP14249.1 - 1.7e-64 215.7 6.7 2.2e-64 215.4 6.7 1.1 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain Gmx_para_CXXCG PF09535.10 KFP14249.1 - 0.0059 15.9 0.2 0.0092 15.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (Gmx_para_CXXCG) HALZ PF02183.18 KFP14249.1 - 0.037 14.2 0.2 0.071 13.3 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper PAP2 PF01569.21 KFP14250.1 - 4.2e-27 94.6 1.3 4.2e-27 94.6 1.3 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFP14250.1 - 0.003 18.0 2.9 0.003 18.0 2.9 2.3 2 1 0 2 2 2 1 PAP2 superfamily C-terminal Cytochrom_B561 PF03188.16 KFP14250.1 - 0.038 14.1 1.3 0.36 11.0 0.2 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 ELM2 PF01448.24 KFP14251.1 - 2e-10 41.3 2.1 4e-10 40.3 0.1 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP14251.1 - 8.3e-07 29.1 1.9 1.1e-06 28.8 0.6 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2002 PF09400.10 KFP14251.1 - 0.049 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) SMN PF06003.12 KFP14251.1 - 6.9 5.8 15.0 1.6 7.9 0.7 3.4 3 1 1 4 4 4 0 Survival motor neuron protein (SMN) MFS_1 PF07690.16 KFP14253.1 - 7.7e-34 117.2 38.8 1.3e-33 116.4 37.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP14253.1 - 1.2e-11 44.1 23.4 1.6e-08 33.8 23.4 3.2 1 1 0 1 1 1 1 MFS_1 like family UQ_con PF00179.26 KFP14254.1 - 1.3e-28 99.4 0.1 1.7e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ion_trans PF00520.31 KFP14255.1 - 1.3e-19 70.5 8.4 1.2e-15 57.4 7.6 2.3 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 KFP14255.1 - 1.1e-18 67.0 0.0 1.9e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP14255.1 - 0.001 19.0 0.1 0.0052 16.7 0.1 2.2 2 0 0 2 2 2 1 Ion channel RNA_pol PF00940.19 KFP14256.1 - 4.7e-160 533.0 0.1 7.2e-160 532.4 0.1 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFP14256.1 - 4.3e-54 184.1 0.0 6.7e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Exog_C PF18026.1 KFP14256.1 - 0.0031 17.5 0.2 0.097 12.7 0.7 3.2 3 0 0 3 3 3 1 Endo/exonuclease (EXOG) C-terminal domain zf-RING_2 PF13639.6 KFP14257.1 - 6.5e-15 55.2 7.4 8.5e-15 54.8 7.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP14257.1 - 2e-10 40.3 7.1 2.8e-10 39.9 7.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP14257.1 - 1.8e-09 37.2 3.4 1.9e-09 37.1 1.7 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP14257.1 - 6.8e-09 35.6 5.0 6.7e-08 32.4 5.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP14257.1 - 2.6e-08 33.6 6.6 3.9e-08 33.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP14257.1 - 6.7e-08 32.7 10.9 1.8e-07 31.3 10.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP14257.1 - 9.8e-08 31.7 2.9 1.5e-07 31.1 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP14257.1 - 1.2e-07 31.6 5.6 1.5e-07 31.2 5.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP14257.1 - 1.7e-06 27.8 8.6 1.3e-05 24.9 8.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP14257.1 - 1.3e-05 25.1 4.0 2.4e-05 24.3 4.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP14257.1 - 0.0019 17.8 6.4 0.0033 17.0 6.4 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 KFP14257.1 - 0.0024 17.7 1.3 0.095 12.5 0.0 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING-like PF08746.11 KFP14257.1 - 0.0046 17.2 5.2 0.0065 16.8 5.2 1.2 1 0 0 1 1 1 1 RING-like domain Vps39_2 PF10367.9 KFP14257.1 - 0.0066 16.9 2.1 3.4 8.1 0.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 2 DUF983 PF06170.12 KFP14257.1 - 0.0069 16.8 0.4 0.59 10.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF983) zf-Nse PF11789.8 KFP14257.1 - 0.027 14.3 7.7 0.052 13.4 7.7 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFP14257.1 - 0.039 14.1 6.2 0.29 11.3 6.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KFP14257.1 - 0.046 13.9 4.4 0.11 12.7 4.4 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KFP14257.1 - 0.048 13.5 7.3 1.4 8.7 7.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 KFP14257.1 - 0.057 13.6 2.2 0.057 13.6 2.2 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family PHD PF00628.29 KFP14257.1 - 0.063 13.2 5.6 0.21 11.5 5.8 1.8 1 1 1 2 2 2 0 PHD-finger NMD3 PF04981.13 KFP14257.1 - 0.08 12.4 0.9 0.11 12.0 0.9 1.2 1 0 0 1 1 1 0 NMD3 family Prok-RING_1 PF14446.6 KFP14257.1 - 0.14 12.1 4.1 5.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KFP14257.1 - 0.2 11.8 9.6 14 5.9 9.6 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-met PF12874.7 KFP14257.1 - 0.21 12.0 2.8 1.1 9.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C3HC4_5 PF17121.5 KFP14257.1 - 0.22 11.4 5.6 4.4 7.3 1.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 KFP14257.1 - 0.25 11.7 6.9 3.6 8.0 6.9 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding YacG PF03884.14 KFP14257.1 - 0.34 10.7 5.1 5.5 6.8 0.5 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Zn-C2H2_12 PF18112.1 KFP14257.1 - 0.56 10.7 8.4 1.8 9.1 0.4 2.7 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 KFP14257.1 - 1.3 9.6 5.2 15 6.2 0.7 2.4 2 1 0 2 2 2 0 Zinc-finger double domain DUF3797 PF12677.7 KFP14257.1 - 2.4 8.1 6.0 8.4 6.4 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-C3H2C3 PF17122.5 KFP14257.1 - 3.9 7.6 12.8 0.28 11.2 5.3 2.3 2 1 0 2 2 2 0 Zinc-finger zf-C2H2_4 PF13894.6 KFP14257.1 - 7.9 7.6 8.3 24 6.1 0.2 2.9 3 1 0 3 3 2 0 C2H2-type zinc finger zf-RING_2 PF13639.6 KFP14258.1 - 8.5e-14 51.6 7.4 8.5e-14 51.6 7.4 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP14258.1 - 2.7e-09 36.7 7.1 2.7e-09 36.7 7.1 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP14258.1 - 1.1e-08 35.2 5.2 1.1e-08 35.2 5.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP14258.1 - 1.3e-08 34.4 1.7 1.3e-08 34.4 1.7 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP14258.1 - 1.5e-07 31.3 5.1 1.9e-07 31.0 2.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP14258.1 - 3.7e-07 29.9 6.6 3.7e-07 29.9 6.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP14258.1 - 1.5e-06 28.0 5.6 1.5e-06 28.0 5.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP14258.1 - 1.7e-06 27.7 2.9 1.7e-06 27.7 2.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP14258.1 - 7.3e-05 22.7 3.8 0.0002 21.3 3.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFP14258.1 - 0.00012 21.8 8.6 0.00012 21.8 8.6 2.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KFP14258.1 - 0.0023 17.5 4.2 0.0057 16.3 4.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KFP14258.1 - 0.0023 17.7 3.3 0.0048 16.7 3.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 KFP14258.1 - 0.0062 16.8 0.5 0.0062 16.8 0.5 3.1 3 0 0 3 3 3 1 zinc-ribbon Vps39_2 PF10367.9 KFP14258.1 - 0.013 15.9 1.1 2.8 8.4 0.5 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.14 KFP14258.1 - 0.052 13.4 4.4 0.54 10.1 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF983 PF06170.12 KFP14258.1 - 0.1 13.0 0.1 4.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) RINGv PF12906.7 KFP14258.1 - 0.43 10.7 4.5 0.9 9.7 4.5 1.6 1 1 0 1 1 1 0 RING-variant domain DUF3678 PF12435.8 KFP14258.1 - 0.5 9.8 0.0 0.5 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Opy2 PF09463.10 KFP14258.1 - 0.53 10.7 4.5 34 4.9 0.1 3.3 3 0 0 3 3 3 0 Opy2 protein PHD PF00628.29 KFP14258.1 - 1.3 8.9 9.9 1.5 8.7 5.4 2.5 2 0 0 2 2 2 0 PHD-finger zf-H2C2_2 PF13465.6 KFP14258.1 - 2.8 8.5 4.8 35 5.1 0.0 3.0 3 0 0 3 3 2 0 Zinc-finger double domain FANCL_C PF11793.8 KFP14258.1 - 2.9 8.1 8.4 50 4.2 8.4 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFP14258.1 - 3 7.7 11.6 5.6 6.8 0.2 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFP14258.1 - 5.6 7.2 10.9 4.7 7.4 7.3 2.6 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KFP14258.1 - 6.1 7.2 12.8 0.061 13.6 5.2 1.6 2 0 0 2 2 1 0 RING-like domain DUF773 PF05600.12 KFP14259.1 - 6e-39 134.1 0.2 6.9e-39 133.9 0.2 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF3849 PF12960.7 KFP14259.1 - 0.039 14.0 0.0 0.046 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) ATAD4 PF15321.6 KFP14260.1 - 3.9e-21 76.2 0.4 9e-21 75.1 0.4 1.5 1 1 0 1 1 1 1 ATPase family AAA domain containing 4 AA_permease_N PF08403.10 KFP14260.1 - 0.035 13.6 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal zf-C2H2 PF00096.26 KFP14261.1 - 4.1e-14 52.1 21.4 1.8e-05 24.9 0.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP14261.1 - 6.8e-12 45.2 16.7 3.5e-06 27.2 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP14261.1 - 2.2e-08 34.3 19.0 0.011 16.5 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP14261.1 - 0.01 16.1 5.0 0.095 13.0 2.3 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP14261.1 - 0.038 14.3 2.6 9.1 6.7 2.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFP14261.1 - 0.073 13.7 4.0 0.67 10.6 1.5 2.8 2 0 0 2 2 2 0 FOXP coiled-coil domain AAA_7 PF12775.7 KFP14261.1 - 0.092 12.3 0.1 0.38 10.2 0.1 1.9 1 1 1 2 2 2 0 P-loop containing dynein motor region zf-C2H2_6 PF13912.6 KFP14261.1 - 0.43 10.6 14.1 0.69 10.0 3.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 KFP14261.1 - 0.48 10.4 3.2 13 5.8 0.7 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger LRR_4 PF12799.7 KFP14263.1 - 4e-15 55.7 5.5 2.2e-07 31.1 0.5 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP14263.1 - 2.2e-11 43.3 5.7 2.3e-05 24.1 0.9 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFP14263.1 - 4.9e-07 29.3 2.3 0.014 15.4 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 KFP14263.1 - 5.9e-06 25.9 0.7 1.5e-05 24.6 0.4 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFP14263.1 - 0.0088 16.4 10.0 1.3 9.8 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat Ras PF00071.22 KFP14264.1 - 1.6e-61 206.6 0.5 1.9e-61 206.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14264.1 - 2e-35 121.6 0.0 3.5e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP14264.1 - 5.1e-12 45.6 0.1 6.4e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP14264.1 - 0.0001 21.7 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP14264.1 - 0.00017 21.6 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP14264.1 - 0.001 19.0 0.4 0.37 10.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP14264.1 - 0.0034 16.9 0.2 0.01 15.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP14264.1 - 0.028 14.8 0.1 0.043 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KFP14264.1 - 0.1 12.0 0.1 0.33 10.4 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit BrnT_toxin PF04365.13 KFP14264.1 - 0.15 12.4 0.1 0.97 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system PCAF_N PF06466.11 KFP14265.1 - 5.4e-105 350.5 2.7 8e-105 349.9 2.7 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KFP14265.1 - 5.1e-24 84.1 0.6 1.1e-23 83.1 0.6 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFP14265.1 - 3.2e-10 40.3 0.1 8.1e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP14265.1 - 1.1e-07 31.8 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP14265.1 - 5.9e-06 26.6 0.2 1.4e-05 25.4 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chalcone_N PF18232.1 KFP14265.1 - 0.029 14.8 0.8 8.2 6.9 0.2 2.6 2 0 0 2 2 2 0 Chalcone isomerase N-terminal domain Ost5 PF05251.12 KFP14266.1 - 4.2e-18 65.4 0.5 4.5e-18 65.3 0.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Phage_holin_3_3 PF16083.5 KFP14266.1 - 0.00052 20.1 0.1 0.00054 20.0 0.1 1.0 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III MPS-4 PF17523.2 KFP14266.1 - 0.16 12.1 1.4 0.17 12.1 1.4 1.1 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 XPG_N PF00752.17 KFP14267.1 - 8.5e-38 128.9 0.0 2.9e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KFP14267.1 - 6.9e-31 106.5 0.4 1.7e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KFP14267.1 - 1.4e-07 32.0 0.0 9.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 KFP14267.1 - 0.0043 17.0 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 KFP14267.1 - 0.019 15.6 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain V_ATPase_I PF01496.19 KFP14268.1 - 2.4e-33 115.1 2.3 2.7e-33 115.0 2.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3021 PF11457.8 KFP14268.1 - 0.02 15.2 3.4 0.024 15.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) PnpCD_PnpD_N PF18191.1 KFP14268.1 - 0.063 12.9 0.1 0.065 12.8 0.1 1.1 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal MOZART1 PF12554.8 KFP14270.1 - 9e-24 83.0 0.4 1e-23 82.8 0.4 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Rad50_zn_hook PF04423.14 KFP14270.1 - 0.041 13.7 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad50 zinc hook motif CBP_BcsN PF17038.5 KFP14270.1 - 0.09 12.1 0.1 0.094 12.1 0.1 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN BORA_N PF15280.6 KFP14271.1 - 1.9e-68 230.6 4.9 8.2e-68 228.5 4.9 2.0 1 1 0 1 1 1 1 Protein aurora borealis N-terminus Secretin_N PF03958.17 KFP14272.1 - 1.5 9.3 3.8 0.89 10.0 0.2 2.5 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain zf-C2H2 PF00096.26 KFP14273.1 - 9.7e-17 60.4 20.9 5.9e-06 26.5 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP14273.1 - 8.3e-12 45.0 7.5 1.7e-07 31.3 1.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP14273.1 - 7.2e-09 35.8 20.3 0.0016 19.1 2.0 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP14273.1 - 0.00063 20.3 4.6 0.1 13.2 0.1 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 KFP14273.1 - 0.0039 17.5 5.7 0.059 13.8 0.6 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP14273.1 - 0.026 14.5 1.4 0.026 14.5 1.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFP14273.1 - 0.041 14.0 5.0 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KFP14273.1 - 0.13 12.2 0.5 0.38 10.7 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type IBR PF01485.21 KFP14273.1 - 0.73 10.1 6.9 3.4 7.9 6.9 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KFP14273.1 - 2.8 8.3 7.8 2.4 8.5 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFP14273.1 - 9 6.0 6.7 2.3 7.9 0.7 2.9 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain RVT_1 PF00078.27 KFP14274.1 - 0.0018 17.9 0.0 0.004 16.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 KFP14275.1 - 3.4e-16 58.7 23.1 5.3e-06 26.6 2.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP14275.1 - 5.6e-11 42.4 9.5 1.3e-07 31.7 1.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP14275.1 - 1.2e-06 28.9 20.2 0.05 14.5 1.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP14275.1 - 0.07 13.5 2.9 7.7 7.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP14275.1 - 0.077 13.3 3.5 6.2 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP14275.1 - 0.12 12.5 2.8 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFP14275.1 - 0.77 10.4 5.2 5.4 7.7 1.0 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFP14275.1 - 1.3 9.2 9.4 0.99 9.5 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFP14275.1 - 5.8 6.6 5.4 2.7 7.7 0.3 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Ccdc124 PF06244.12 KFP14276.1 - 2.1e-42 144.7 9.2 2.1e-42 144.7 9.2 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KFP14276.1 - 0.0021 18.5 0.8 0.0021 18.5 0.8 2.8 2 1 1 3 3 3 1 HMG (high mobility group) box UPF0240 PF06784.11 KFP14276.1 - 0.15 12.1 13.0 0.028 14.5 9.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) DUF2866 PF11065.8 KFP14276.1 - 0.16 12.0 0.4 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) Asp-B-Hydro_N PF05279.11 KFP14276.1 - 2.2 8.3 23.4 2.6 8.0 23.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMEM214 PF10151.9 KFP14276.1 - 4.4 5.6 12.7 5.3 5.4 12.7 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Pkinase PF00069.25 KFP14277.1 - 3.4e-65 220.0 0.2 5.8e-65 219.3 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14277.1 - 1.2e-38 132.9 0.2 1.6e-38 132.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14277.1 - 8.7e-14 51.5 0.1 1.2e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP14277.1 - 0.00088 18.3 0.6 0.0018 17.3 0.6 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP14277.1 - 0.0022 18.0 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP14277.1 - 0.0032 16.3 1.2 0.0048 15.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DDE_Tnp_4 PF13359.6 KFP14277.1 - 0.048 13.3 0.2 0.092 12.4 0.2 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Endonuclease_5 PF04493.14 KFP14277.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Endonuclease V Lipocalin PF00061.23 KFP14278.1 - 3.9e-18 66.0 0.0 5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFP14278.1 - 8.1e-10 38.8 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.13 KFP14278.1 - 1.4e-05 25.0 0.1 0.00098 19.0 0.0 2.1 2 0 0 2 2 2 2 Triabin PDEase_I PF00233.19 KFP14279.1 - 1.5e-78 263.8 4.7 1.5e-78 263.8 4.7 1.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFP14279.1 - 2.7e-28 99.2 0.0 6.9e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFP14279.1 - 1.2e-10 41.8 0.0 0.00027 21.2 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFP14279.1 - 3.7e-07 30.5 0.0 0.00067 20.0 0.0 2.7 2 1 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFP14279.1 - 4.6e-05 23.5 0.1 0.035 14.1 0.0 3.4 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor Cut12 PF11500.8 KFP14279.1 - 0.011 15.7 0.4 0.025 14.5 0.4 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF4316 PF14195.6 KFP14279.1 - 0.11 12.3 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) SANT_DAMP1_like PF16282.5 KFP14279.1 - 0.52 10.5 0.1 0.52 10.5 0.1 2.8 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF1211 PF06736.11 KFP14280.1 - 2.9e-34 117.4 3.4 3.7e-22 78.6 0.0 3.6 4 1 0 4 4 4 2 Protein of unknown function (DUF1211) S-AdoMet_synt_C PF02773.16 KFP14281.1 - 3.3e-67 224.7 0.0 7.3e-67 223.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFP14281.1 - 1.4e-41 141.5 0.0 4.9e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFP14281.1 - 1.3e-39 134.9 0.5 2.6e-39 133.9 0.5 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Phosphodiest PF01663.22 KFP14282.1 - 1e-12 48.3 0.3 1.1e-08 35.0 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFP14282.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily TraB PF01963.17 KFP14284.1 - 6.6e-38 131.1 0.0 7.6e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 TraB family TraB PF01963.17 KFP14285.1 - 7.6e-23 81.7 0.0 8.4e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 TraB family Neur_chan_LBD PF02931.23 KFP14286.1 - 3.1e-71 239.3 2.2 4.2e-71 238.8 2.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP14286.1 - 4.6e-57 193.8 0.5 5.8e-57 193.5 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TcpE PF12648.7 KFP14286.1 - 1.5 9.4 5.9 0.74 10.4 1.4 2.3 2 0 0 2 2 2 0 TcpE family Histone PF00125.24 KFP14287.1 - 2.1e-20 73.4 0.0 2.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP14287.1 - 0.004 17.4 1.4 0.0042 17.3 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP14287.1 - 0.0095 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Myb_DNA-bind_6 PF13921.6 KFP14288.1 - 8e-16 58.1 10.7 3e-14 53.0 0.8 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFP14288.1 - 3.7e-14 52.6 17.8 1.3e-09 38.1 0.2 3.8 4 1 0 4 4 4 2 Myb-like DNA-binding domain WbqC PF08889.11 KFP14288.1 - 0.0055 16.6 1.5 0.086 12.7 0.0 2.8 2 1 1 3 3 3 1 WbqC-like protein family Poxvirus_B22R_N PF13169.6 KFP14288.1 - 0.0064 16.9 0.3 0.0064 16.9 0.3 2.9 3 0 0 3 3 3 1 Poxvirus B22R protein N-terminal MMTV_SAg PF01054.17 KFP14288.1 - 0.037 13.6 1.5 0.082 12.4 1.5 1.6 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen MIX PF18529.1 KFP14288.1 - 0.1 12.3 0.0 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial membrane-anchored proteins DUF4845 PF16137.5 KFP14288.1 - 0.13 13.1 0.9 9 7.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) DUF4897 PF16238.5 KFP14288.1 - 0.21 11.4 3.3 0.21 11.4 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4897) AAA_11 PF13086.6 KFP14289.1 - 1.5e-64 218.3 3.6 1.5e-64 218.3 3.6 3.4 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KFP14289.1 - 3e-54 183.7 0.0 3e-54 183.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain SEN1_N PF12726.7 KFP14289.1 - 4.6e-14 51.6 1.3 1.4e-13 50.0 1.2 1.8 1 1 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.6 KFP14289.1 - 2.7e-09 37.5 0.0 3e-08 34.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFP14289.1 - 1.2e-07 31.7 0.2 0.0024 17.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KFP14289.1 - 4.5e-07 29.8 0.5 0.17 11.6 0.1 3.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFP14289.1 - 9.5e-05 22.7 1.2 0.00057 20.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KFP14289.1 - 0.00049 20.5 0.0 0.0023 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.21 KFP14289.1 - 0.0037 16.8 1.1 0.0037 16.8 1.1 3.6 2 2 1 3 3 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KFP14289.1 - 0.005 16.9 0.1 0.033 14.2 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KFP14289.1 - 0.071 13.0 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 Helicase RNA_helicase PF00910.22 KFP14289.1 - 0.094 13.1 0.0 0.46 10.9 0.0 2.3 1 0 0 1 1 1 0 RNA helicase DUF4164 PF13747.6 KFP14289.1 - 0.56 10.5 5.2 1.8 8.9 5.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4284 PF14112.6 KFP14289.1 - 4.5 8.2 10.1 4.2 8.3 1.6 3.6 3 0 0 3 3 3 0 Immunity protein 22 Laminin_N PF00055.17 KFP14290.1 - 1.5e-49 168.8 0.0 1.5e-49 168.8 0.0 3.4 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFP14290.1 - 1.3e-20 73.2 69.1 1.2e-08 34.9 14.1 4.7 3 1 1 4 4 4 3 Laminin EGF domain EGF PF00008.27 KFP14290.1 - 0.005 17.1 7.5 0.005 17.1 7.5 6.3 5 2 2 7 7 7 1 EGF-like domain BNR PF02012.20 KFP14290.1 - 0.011 15.6 1.1 1.5 9.2 0.0 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat 7tm_4 PF13853.6 KFP14292.1 - 7.3e-25 88.2 10.1 1.1e-12 48.3 1.4 2.0 1 1 1 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFP14292.1 - 1.8e-13 50.4 8.7 2.5e-11 43.4 3.6 2.2 1 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Rax2 PF12768.7 KFP14292.1 - 0.075 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CholecysA-Rec_N PF09193.10 KFP14292.1 - 0.11 12.6 0.1 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal 7tm_1 PF00001.21 KFP14293.1 - 1.9e-22 79.8 3.7 2.5e-22 79.5 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP14293.1 - 5.1e-20 72.4 4.1 6.1e-20 72.1 4.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP14293.1 - 1.2e-05 24.8 4.0 1.6e-05 24.4 4.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cyclin_N PF00134.23 KFP14294.1 - 6.7e-14 51.7 0.0 6.7e-14 51.7 0.0 2.4 3 0 0 3 3 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP14294.1 - 0.00014 21.9 0.1 0.00014 21.9 0.1 2.3 1 1 1 2 2 1 1 Cyclin, C-terminal domain DAG_kinase_N PF14513.6 KFP14294.1 - 0.0071 16.6 5.9 0.013 15.7 5.9 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus DDHD PF02862.17 KFP14294.1 - 0.017 15.3 4.3 0.03 14.5 4.3 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 KFP14294.1 - 0.12 12.2 10.5 0.18 11.6 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAR2 PF05282.11 KFP14294.1 - 0.51 9.7 6.9 0.72 9.2 6.9 1.1 1 0 0 1 1 1 0 AAR2 protein Lin-8 PF03353.15 KFP14294.1 - 3.1 7.3 16.4 4.6 6.7 16.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 KFP14294.1 - 5.7 6.9 9.6 9.2 6.2 9.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 KFP14294.1 - 5.9 7.9 9.9 11 7.0 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 KFP14294.1 - 7.4 5.2 15.9 11 4.7 15.9 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 KFP14294.1 - 8.1 6.2 9.0 12 5.6 9.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SpoIIP PF07454.11 KFP14294.1 - 9.6 5.6 11.2 14 5.0 11.2 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) GSDH PF07995.11 KFP14295.1 - 2.9e-39 135.3 0.0 3.8e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFP14295.1 - 1e-06 28.7 1.1 1e-06 28.7 1.1 1.6 2 0 0 2 2 2 1 Folate receptor family p450 PF00067.22 KFP14296.1 - 3.7e-90 302.9 0.4 4.7e-90 302.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_2 PF03567.14 KFP14296.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Sulfotransferase family PIP49_C PF12260.8 KFP14297.1 - 2.3e-06 27.4 0.1 4.2e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Nodulin_late PF07127.11 KFP14297.1 - 0.29 11.5 3.6 0.69 10.3 1.3 2.3 2 0 0 2 2 2 0 Late nodulin protein HELP PF03451.14 KFP14298.1 - 1.5e-31 108.0 0.1 3e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KFP14298.1 - 1.2e-27 95.6 41.1 0.00021 22.0 0.8 10.8 10 1 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14298.1 - 2.1e-06 27.9 0.2 0.00065 19.9 0.0 4.6 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PKcGMP_CC PF16808.5 KFP14298.1 - 0.048 13.5 0.2 0.098 12.5 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DPPIV_N PF00930.21 KFP14298.1 - 0.05 12.4 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SlyX PF04102.12 KFP14298.1 - 0.67 10.6 2.5 0.73 10.5 1.3 1.7 2 0 0 2 2 2 0 SlyX FA_desaturase PF00487.24 KFP14299.1 - 1.8e-25 90.3 18.2 3.3e-25 89.4 18.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KFP14299.1 - 4.1e-06 26.2 0.3 1e-05 24.9 0.3 1.8 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2 PF00096.26 KFP14300.1 - 2.9e-19 68.3 23.3 8.9e-06 25.9 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP14300.1 - 1e-16 60.5 21.7 2.5e-07 30.8 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP14300.1 - 3.9e-12 45.9 24.6 0.01 16.6 0.2 4.6 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFP14300.1 - 0.00055 20.1 6.4 1.5 8.9 0.1 3.2 1 1 2 3 3 3 2 Aberrant zinc-finger zf-TRAF PF02176.18 KFP14300.1 - 0.0068 17.1 12.3 2.6 8.8 0.1 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger Transpos_assoc PF13963.6 KFP14300.1 - 0.0078 16.5 5.6 0.29 11.5 0.1 3.3 2 1 1 3 3 3 1 Transposase-associated domain IBR PF01485.21 KFP14300.1 - 0.0087 16.3 1.6 0.0087 16.3 1.6 3.2 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Raffinose_syn PF05691.12 KFP14300.1 - 0.011 13.6 0.0 0.014 13.3 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 CHORD PF04968.12 KFP14300.1 - 0.014 16.1 11.6 4.3 8.1 2.1 3.8 1 1 3 4 4 4 0 CHORD zinc_ribbon_9 PF14369.6 KFP14300.1 - 0.02 15.2 3.1 0.94 9.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon CCAP PF11105.8 KFP14300.1 - 0.022 14.7 4.5 0.39 10.7 0.7 2.3 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf_UBZ PF18439.1 KFP14300.1 - 0.03 13.9 0.9 1.5 8.5 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-CGNR PF11706.8 KFP14300.1 - 0.043 13.7 6.9 3 7.8 0.8 3.4 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_11 PF16622.5 KFP14300.1 - 0.072 12.9 7.2 1.6 8.5 0.4 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type XPA_N PF01286.18 KFP14300.1 - 0.5 10.4 4.6 1.5 9.0 0.1 3.1 4 0 0 4 4 3 0 XPA protein N-terminal FOXP-CC PF16159.5 KFP14300.1 - 2.6 8.7 7.8 11 6.8 1.9 2.9 3 1 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFP14300.1 - 4.1 7.8 20.2 4 7.8 0.4 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.27 KFP14301.1 - 5.3e-62 205.8 2.2 1.3e-22 79.6 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KFP14302.1 - 1.4e-67 223.7 0.6 1.1e-23 82.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1b PF00579.25 KFP14303.1 - 5.9e-23 81.6 0.0 1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 KFP14303.1 - 2.7e-21 75.5 0.1 6.3e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain WD40 PF00400.32 KFP14304.1 - 1.4e-21 76.4 6.5 7.8e-05 23.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14304.1 - 4.1e-12 46.2 0.0 6.2e-05 23.2 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP14304.1 - 1.6e-09 38.0 0.0 0.0012 18.8 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP14304.1 - 0.00088 18.3 0.2 0.011 14.8 0.0 2.4 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP14304.1 - 0.0092 14.7 0.9 0.02 13.6 0.3 1.8 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Rab5-bind PF09311.11 KFP14305.1 - 0.00045 19.7 6.1 0.0011 18.4 6.1 1.6 1 0 0 1 1 1 1 Rabaptin-like protein IFT57 PF10498.9 KFP14305.1 - 0.02 13.9 7.8 0.051 12.5 7.8 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KFP14305.1 - 0.027 13.4 12.2 0.071 12.0 9.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 KFP14305.1 - 0.068 12.8 10.4 0.17 11.5 10.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 KFP14305.1 - 0.14 12.5 5.0 0.32 11.3 5.0 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Homeodomain PF00046.29 KFP14305.1 - 0.45 10.4 2.9 0.55 10.1 1.0 2.2 2 0 0 2 2 2 0 Homeodomain DUF1664 PF07889.12 KFP14305.1 - 0.95 9.5 4.7 1.1 9.3 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 KFP14305.1 - 2 6.9 7.7 3.2 6.3 7.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tup_N PF08581.10 KFP14305.1 - 3.2 8.1 13.0 1.8 8.9 9.9 2.3 2 0 0 2 2 2 0 Tup N-terminal XhlA PF10779.9 KFP14305.1 - 5.3 7.3 5.1 1.1 9.5 1.3 1.9 2 0 0 2 2 2 0 Haemolysin XhlA RVT_1 PF00078.27 KFP14306.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.27 KFP14308.1 - 2.4e-30 104.5 83.8 7.5e-08 32.5 9.0 6.8 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KFP14308.1 - 1.8e-14 53.7 76.6 0.00037 21.0 5.3 7.9 7 0 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 KFP14308.1 - 9.4e-13 48.3 98.4 0.00036 20.8 9.2 6.3 6 0 0 6 6 6 6 EGF-like domain DUF2448 PF10476.9 KFP14308.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Laminin_EGF PF00053.24 KFP14308.1 - 2.2 8.5 69.9 0.13 12.4 7.6 6.5 3 2 3 6 6 6 0 Laminin EGF domain EGF_CA PF07645.15 KFP14308.1 - 5.1 7.4 80.7 0.11 12.7 9.2 6.7 3 2 3 6 6 6 0 Calcium-binding EGF domain T4_deiodinase PF00837.17 KFP14309.1 - 1e-35 123.1 0.0 1.2e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase US22 PF02393.16 KFP14309.1 - 0.16 12.2 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 US22 like T4_deiodinase PF00837.17 KFP14310.1 - 2.9e-54 183.9 0.0 3.3e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase B56 PF01603.20 KFP14311.1 - 1.6e-200 666.4 10.8 2.1e-200 666.0 10.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFP14311.1 - 0.15 12.0 1.8 2.1 8.3 0.3 2.8 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HSP90 PF00183.18 KFP14312.1 - 9.6e-235 780.3 33.7 1.2e-234 780.0 33.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFP14312.1 - 4.3e-14 53.0 0.1 9.9e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP14312.1 - 6.3e-12 45.5 0.1 2e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KFP14312.1 - 0.1 12.6 1.3 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF1198 PF06711.11 KFP14312.1 - 0.21 11.7 0.6 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Zip PF02535.22 KFP14312.1 - 0.25 10.5 0.6 0.54 9.4 0.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KFP14312.1 - 2.9 6.1 14.1 5.7 5.1 14.1 1.4 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 KFP14313.1 - 9.1e-12 45.3 3.7 0.00025 21.8 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14313.1 - 4.2e-08 33.4 0.0 0.61 10.4 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFP14313.1 - 0.00022 21.0 0.2 1 9.4 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFP14313.1 - 0.026 13.5 0.0 0.082 11.9 0.0 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP14313.1 - 0.048 13.5 0.0 0.26 11.1 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 KFP14314.1 - 4.4e-68 229.5 0.0 5.6e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14314.1 - 4.4e-30 104.8 0.0 6.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14314.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP14314.1 - 0.013 14.9 0.1 0.026 13.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFP14314.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF4764 PF15961.5 KFP14315.1 - 5.6e-23 81.6 1.2 6.1e-23 81.5 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) S-antigen PF05756.11 KFP14315.1 - 0.25 11.7 1.7 0.41 11.1 1.7 1.3 1 0 0 1 1 1 0 S-antigen protein AAA_8 PF12780.7 KFP14316.1 - 0.0068 15.8 0.8 0.0083 15.5 0.8 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Hyd_WA PF06462.12 KFP14317.1 - 5.4e-37 125.5 19.0 1e-06 28.6 0.9 8.5 8 0 0 8 8 8 6 Propeller ANAPC4_WD40 PF12894.7 KFP14317.1 - 0.0013 19.0 0.0 0.0043 17.3 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP14317.1 - 0.0019 19.0 0.0 0.066 14.1 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat WD40_like PF17005.5 KFP14317.1 - 0.023 14.0 0.0 0.13 11.5 0.1 1.7 1 1 1 2 2 2 0 WD40-like domain Myb_DNA-binding PF00249.31 KFP14318.1 - 5.5e-17 61.7 0.8 2.3e-09 37.3 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP14318.1 - 8.9e-06 25.5 12.7 0.00094 19.0 0.1 3.3 3 1 0 3 3 3 2 Myb DNA-binding like ELM2 PF01448.24 KFP14318.1 - 7.6e-05 23.4 0.0 7.6e-05 23.4 0.0 2.9 2 1 0 2 2 2 1 ELM2 domain Myb_DNA-bind_6 PF13921.6 KFP14318.1 - 0.00017 21.8 4.1 0.12 12.6 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Arnt_C PF18583.1 KFP14318.1 - 0.0083 15.7 0.5 4 7.1 0.1 2.7 2 0 0 2 2 2 2 Aminoarabinose transferase C-terminal domain Homeobox_KN PF05920.11 KFP14318.1 - 0.064 13.2 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain FAM76 PF16046.5 KFP14318.1 - 0.59 9.4 8.6 1.2 8.5 8.6 1.4 1 0 0 1 1 1 0 FAM76 protein RR_TM4-6 PF06459.12 KFP14318.1 - 2.1 8.1 12.7 0.14 11.9 6.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DivIC PF04977.15 KFP14318.1 - 9.1 6.1 8.3 3.2 7.6 0.7 3.4 4 0 0 4 4 4 0 Septum formation initiator zf-TRAF PF02176.18 KFP14319.1 - 1.5e-25 89.6 24.5 7.5e-16 58.6 9.4 4.4 1 1 3 4 4 3 2 TRAF-type zinc finger Sina PF03145.16 KFP14319.1 - 0.00023 21.2 16.4 0.0014 18.6 6.5 3.7 2 1 2 4 4 3 2 Seven in absentia protein family MPS2 PF17060.5 KFP14319.1 - 0.00073 18.9 6.3 0.0011 18.3 6.3 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 Cast PF10174.9 KFP14319.1 - 0.0027 16.0 11.6 0.0035 15.6 10.7 1.6 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.11 KFP14319.1 - 0.0028 17.9 6.3 0.0028 17.9 6.3 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) zf-C3HC4 PF00097.25 KFP14319.1 - 0.0064 16.3 15.8 0.0064 16.3 15.8 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FliJ PF02050.16 KFP14319.1 - 0.0094 16.2 9.3 0.01 16.0 8.3 1.6 1 1 0 1 1 1 1 Flagellar FliJ protein zf-C3HC4_2 PF13923.6 KFP14319.1 - 0.021 14.7 14.6 0.021 14.7 14.6 3.3 2 1 2 4 4 2 0 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 KFP14319.1 - 0.028 13.3 14.7 0.042 12.7 14.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 KFP14319.1 - 0.072 12.9 6.0 0.041 13.7 3.7 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Tropomyosin_1 PF12718.7 KFP14319.1 - 0.091 12.9 15.5 0.41 10.8 15.5 2.3 1 1 0 1 1 1 0 Tropomyosin like SPATA24 PF15175.6 KFP14319.1 - 0.093 12.6 13.4 0.091 12.6 8.0 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 KxDL PF10241.9 KFP14319.1 - 0.12 12.7 5.7 0.1 12.9 3.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein T3SSipB PF16535.5 KFP14319.1 - 0.13 12.8 3.8 0.11 13.0 2.2 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 KFP14319.1 - 0.13 12.3 5.4 0.24 11.4 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_6 PF14835.6 KFP14319.1 - 0.13 12.1 5.7 0.22 11.4 4.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein BLOC1_2 PF10046.9 KFP14319.1 - 0.14 12.4 8.3 0.21 11.9 3.9 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 KFP14319.1 - 0.17 12.0 15.8 0.077 13.1 10.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 KFP14319.1 - 1.4 8.1 6.8 2.4 7.3 6.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 KFP14319.1 - 1.5 8.3 9.7 2.3 7.7 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KFP14319.1 - 1.5 7.6 4.4 2.2 7.1 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Amnionless PF14828.6 KFP14320.1 - 1.1e-123 413.5 0.0 1.2e-123 413.3 0.0 1.0 1 0 0 1 1 1 1 Amnionless CNH PF00780.22 KFP14321.1 - 3.6e-72 243.3 0.1 6.8e-72 242.4 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP14321.1 - 6.1e-56 189.7 2.5 8.3e-56 189.3 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain KELK PF15796.5 KFP14321.1 - 6.8e-32 109.8 20.1 6.8e-32 109.8 20.1 7.1 6 2 3 9 9 6 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Pkinase_Tyr PF07714.17 KFP14321.1 - 4.3e-29 101.6 0.0 4.3e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DMPK_coil PF08826.10 KFP14321.1 - 3.1e-26 91.2 11.3 3.1e-26 91.2 11.3 9.2 7 2 3 10 10 10 1 DMPK coiled coil domain like C1_1 PF00130.22 KFP14321.1 - 4.6e-10 39.2 5.9 1e-09 38.1 5.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP14321.1 - 5.1e-07 29.3 0.0 1.6e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 KFP14321.1 - 0.00086 19.6 0.2 0.0039 17.5 0.2 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Myosin_tail_1 PF01576.19 KFP14321.1 - 0.00092 17.2 102.8 0.0033 15.3 76.2 3.4 1 1 2 3 3 3 2 Myosin tail Pkinase_C PF00433.24 KFP14321.1 - 0.0015 19.2 0.8 0.0036 18.0 0.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH PF00169.29 KFP14321.1 - 0.014 15.9 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 0 PH domain C1_2 PF03107.16 KFP14321.1 - 0.016 15.5 5.0 0.043 14.1 5.0 1.7 1 0 0 1 1 1 0 C1 domain Filament PF00038.21 KFP14321.1 - 0.17 11.5 83.2 0.018 14.6 2.2 5.2 2 1 3 5 5 5 0 Intermediate filament protein DUF3450 PF11932.8 KFP14321.1 - 0.43 9.8 67.7 0.054 12.8 6.8 5.5 2 1 4 6 6 6 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 KFP14321.1 - 8.9 6.3 17.8 4.6 7.3 0.6 4.2 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lbh PF15317.6 KFP14322.1 - 1.5e-18 67.5 0.4 1.7e-18 67.3 0.4 1.0 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Sec6 PF06046.13 KFP14324.1 - 5.8e-71 239.6 2.5 7.9e-71 239.1 2.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Ribosomal_L18_c PF14204.6 KFP14324.1 - 0.85 10.6 4.9 19 6.3 0.1 3.2 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region Sec6 PF06046.13 KFP14325.1 - 5.9e-78 262.7 5.0 6.7e-78 262.5 5.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 HD_2 PF12917.7 KFP14325.1 - 0.12 12.1 4.8 6.6 6.4 0.1 3.2 3 0 0 3 3 3 0 HD containing hydrolase-like enzyme 7tm_1 PF00001.21 KFP14326.1 - 3.2e-79 266.0 11.8 3.8e-79 265.7 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14326.1 - 3.9e-17 62.5 6.4 7.4e-17 61.6 6.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP14326.1 - 1.4e-06 28.2 14.1 1.1e-05 25.4 7.0 3.0 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP14326.1 - 7.8e-06 25.7 14.1 7.8e-06 25.7 14.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Amino_oxidase PF01593.24 KFP14327.1 - 3.6e-79 267.2 0.0 4.8e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP14327.1 - 5e-15 55.5 0.5 1e-14 54.5 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP14327.1 - 5.3e-06 26.3 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFP14327.1 - 1.6e-05 24.2 1.3 2.5e-05 23.5 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFP14327.1 - 0.00021 21.8 0.8 0.00093 19.7 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP14327.1 - 0.00033 20.0 0.0 0.0008 18.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFP14327.1 - 0.0024 17.0 0.3 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFP14327.1 - 0.003 16.3 0.2 0.0075 15.0 0.2 1.6 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KFP14327.1 - 0.0054 16.1 0.2 0.0075 15.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFP14327.1 - 0.0069 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KFP14327.1 - 0.0072 15.6 1.7 0.011 15.1 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFP14327.1 - 0.0087 15.3 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 KFP14327.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KFP14327.1 - 0.01 15.1 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFP14327.1 - 0.035 13.2 0.5 0.16 11.0 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 KFP14327.1 - 0.055 11.9 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KFP14327.1 - 0.074 13.0 0.6 0.2 11.6 0.3 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 KFP14327.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 KFP14327.1 - 0.21 11.5 0.8 6.4 6.6 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sen15 PF09631.10 KFP14328.1 - 7.9e-27 93.5 0.0 1e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein PCNA_C PF02747.15 KFP14328.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain GON PF08685.11 KFP14329.1 - 0.23 11.3 0.0 0.23 11.3 0.0 1.0 1 0 0 1 1 1 0 GON domain DUF4612 PF15389.6 KFP14330.1 - 9.2e-38 129.8 4.8 1e-37 129.7 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) Glyco_hydro_47 PF01532.20 KFP14331.1 - 4.5e-115 385.2 0.0 8.5e-115 384.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KFP14331.1 - 4.5e-12 45.8 0.1 9.1e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 PA domain Glyco_hydro_127 PF07944.12 KFP14331.1 - 0.13 10.7 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 RAWUL PF16207.5 KFP14333.1 - 6.3e-30 103.7 0.2 1.4e-29 102.6 0.2 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP14333.1 - 4.8e-16 58.3 10.3 8.1e-16 57.6 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP14333.1 - 5.6e-10 38.9 10.4 1e-09 38.1 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP14333.1 - 5.4e-09 36.2 8.5 9.2e-09 35.5 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP14333.1 - 6.2e-08 32.4 7.9 9.3e-08 31.8 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP14333.1 - 5.6e-06 26.3 8.0 1.1e-05 25.3 8.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP14333.1 - 1.6e-05 24.7 8.5 3e-05 23.9 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP14333.1 - 4.9e-05 23.4 7.6 9.6e-05 22.5 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFP14333.1 - 0.00021 21.1 5.5 0.00036 20.3 5.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFP14333.1 - 0.00023 20.9 6.6 0.00048 19.8 6.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFP14333.1 - 0.001 18.9 3.7 0.0018 18.1 3.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KFP14333.1 - 0.0015 18.7 7.1 0.0046 17.2 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 KFP14333.1 - 0.035 14.0 7.1 0.34 10.8 7.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFP14333.1 - 0.042 13.9 1.9 0.14 12.3 1.9 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 KFP14333.1 - 0.066 13.1 8.4 0.9 9.4 8.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP14333.1 - 0.21 11.6 2.5 0.43 10.7 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFP14333.1 - 0.39 10.5 4.6 0.95 9.3 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 KFP14333.1 - 0.76 9.6 6.8 1.5 8.7 6.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C4_Topoisom PF01396.19 KFP14333.1 - 2.1 8.2 5.1 0.27 11.1 0.9 1.7 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger TRM PF02005.16 KFP14334.1 - 9e-63 212.7 3.9 2.7e-51 174.9 0.4 3.2 2 1 0 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KFP14334.1 - 0.0021 17.8 0.2 0.0049 16.6 0.2 1.5 1 0 0 1 1 1 1 Met-10+ like-protein CUB PF00431.20 KFP14335.1 - 0.0072 16.6 0.3 0.02 15.2 0.1 1.7 1 1 1 2 2 2 1 CUB domain DUF953 PF06110.11 KFP14335.1 - 0.02 14.5 0.9 0.11 12.1 0.0 2.0 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) LEF-4 PF05098.12 KFP14335.1 - 0.059 12.2 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 4 (LEF-4) WDCP PF15390.6 KFP14335.1 - 0.061 11.7 1.6 0.072 11.5 1.6 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PIN_4 PF13638.6 KFP14336.1 - 3.2e-31 108.3 0.1 1.1e-30 106.6 0.1 1.9 2 0 0 2 2 2 1 PIN domain PIN_12 PF16289.5 KFP14336.1 - 0.0011 19.5 0.7 0.0079 16.7 0.0 2.4 2 0 0 2 2 2 1 PIN domain PIN_9 PF18477.1 KFP14336.1 - 0.0021 18.3 0.6 0.02 15.2 0.1 2.9 3 1 0 3 3 3 1 PIN like domain Kelch_1 PF01344.25 KFP14337.1 - 7e-86 281.6 12.0 2.3e-15 55.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP14337.1 - 1.3e-48 161.8 2.4 2.4e-10 40.3 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP14337.1 - 2.9e-40 135.8 7.6 1.6e-08 34.6 0.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP14337.1 - 9.9e-37 123.6 1.5 8e-05 22.5 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFP14337.1 - 1.9e-33 114.2 2.1 9.9e-07 28.7 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFP14337.1 - 9.4e-27 93.4 0.5 1.4e-26 92.9 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KFP14337.1 - 2.5e-16 59.3 4.8 0.0014 18.6 0.0 6.1 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP14337.1 - 5.7e-13 48.9 0.1 3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch XPA_C PF05181.12 KFP14337.1 - 0.34 10.9 4.1 38 4.3 0.0 4.3 6 0 0 6 6 6 0 XPA protein C-terminus PQQ_3 PF13570.6 KFP14337.1 - 0.56 10.8 7.4 6.8 7.3 0.1 4.6 5 0 0 5 5 5 0 PQQ-like domain GON PF08685.11 KFP14340.1 - 0.14 12.1 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 GON domain I-set PF07679.16 KFP14341.1 - 0 2252.3 0.0 4.4e-20 71.5 0.1 44.3 44 0 0 44 44 44 44 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP14341.1 - 0 2022.4 88.8 5.2e-17 62.2 0.2 44.6 44 0 0 44 44 44 44 Immunoglobulin domain Ig_2 PF13895.6 KFP14341.1 - 0 1402.6 52.0 1.7e-12 47.5 0.0 44.8 44 1 1 45 45 44 42 Immunoglobulin domain ig PF00047.25 KFP14341.1 - 0 1145.6 2.3 8.9e-11 41.8 0.1 44.9 43 1 1 44 44 44 42 Immunoglobulin domain V-set PF07686.17 KFP14341.1 - 6.7e-138 451.0 102.9 0.0008 19.6 0.1 69.3 48 30 7 56 56 56 29 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP14341.1 - 8.7e-105 343.0 50.6 0.011 15.8 0.0 41.1 42 0 0 42 42 42 24 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP14341.1 - 1.2e-92 303.3 8.9 0.11 12.1 0.0 42.8 47 0 0 47 47 44 18 Immunoglobulin domain Ig_5 PF16681.5 KFP14341.1 - 6.7e-81 266.8 0.0 0.044 14.2 0.0 39.7 43 0 0 43 43 42 12 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain EGF_CA PF07645.15 KFP14341.1 - 9.1e-63 208.2 121.3 1.1e-12 47.9 7.0 10.1 9 0 0 9 9 8 8 Calcium-binding EGF domain Ig_4 PF16680.5 KFP14341.1 - 2.4e-58 194.3 0.0 0.048 13.9 0.0 37.2 40 1 0 40 40 40 8 T-cell surface glycoprotein CD3 delta chain TSP_1 PF00090.19 KFP14341.1 - 1.2e-55 185.5 149.0 1.4e-13 50.8 6.1 8.5 10 0 0 10 10 6 6 Thrombospondin type 1 domain G2F PF07474.12 KFP14341.1 - 1.8e-53 181.0 0.1 3.6e-53 180.1 0.1 1.5 1 0 0 1 1 1 1 G2F domain cEGF PF12662.7 KFP14341.1 - 3.2e-46 154.8 66.5 1.4e-11 44.1 2.7 10.4 9 0 0 9 9 9 8 Complement Clr-like EGF-like Izumo-Ig PF16706.5 KFP14341.1 - 2.3e-42 142.9 12.1 1.2 9.3 0.0 33.8 39 0 0 39 39 38 4 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFP14341.1 - 7.7e-33 112.9 5.1 0.45 10.7 0.0 25.5 33 0 0 33 33 29 3 Natural killer cell receptor 2B4 C1-set PF07654.15 KFP14341.1 - 2.3e-32 111.2 6.5 0.27 11.7 0.0 28.3 34 0 0 34 34 30 2 Immunoglobulin C1-set domain C2-set PF05790.15 KFP14341.1 - 1.6e-18 66.6 0.6 2.5 8.4 0.0 20.7 28 0 0 28 28 23 2 Immunoglobulin C2-set domain FXa_inhibition PF14670.6 KFP14341.1 - 5.6e-10 39.3 147.3 7.9e-06 26.1 11.8 10.6 11 1 1 12 12 8 6 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP14341.1 - 1.1e-05 25.5 113.6 0.00023 21.3 7.8 9.6 9 0 0 9 9 9 5 EGF domain EGF PF00008.27 KFP14341.1 - 0.0019 18.4 7.3 0.0019 18.4 7.3 10.7 8 1 1 9 9 8 5 EGF-like domain Peptidase_S9_N PF02897.15 KFP14341.1 - 0.0036 16.2 0.1 21 3.7 0.0 5.8 6 0 0 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain ANAPC4_WD40 PF12894.7 KFP14341.1 - 0.087 13.1 0.0 6.7 7.1 0.0 4.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_MLP1_2 PF07926.12 KFP14343.1 - 3.1e-33 114.6 31.4 3.1e-33 114.6 31.4 16.1 7 4 9 16 16 16 8 TPR/MLP1/MLP2-like protein GRP PF07172.11 KFP14343.1 - 6 7.6 8.2 77 4.1 8.2 3.1 1 0 0 1 1 1 0 Glycine rich protein family ODR4-like PF14778.6 KFP14344.1 - 4.2e-118 394.5 2.6 5.6e-118 394.1 2.6 1.2 1 0 0 1 1 1 1 Olfactory receptor 4-like Phosducin PF02114.16 KFP14345.1 - 5.2e-114 379.7 2.2 5.6e-114 379.5 2.2 1.0 1 0 0 1 1 1 1 Phosducin An_peroxidase PF03098.15 KFP14346.1 - 9.9e-55 186.1 0.0 3.4e-48 164.5 0.0 2.3 1 1 1 2 2 2 2 Animal haem peroxidase EGF PF00008.27 KFP14346.1 - 2.9e-05 24.3 13.8 6.1e-05 23.2 13.8 1.6 1 0 0 1 1 1 1 EGF-like domain PLA2_B PF01735.18 KFP14347.1 - 3.9e-158 526.9 0.0 4.9e-158 526.6 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.30 KFP14347.1 - 1.6e-16 60.5 0.1 3.2e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain DUF2281 PF10047.9 KFP14347.1 - 0.062 14.0 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) RVT_1 PF00078.27 KFP14348.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1708 PF08101.11 KFP14352.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Zw10 PF06248.13 KFP14354.1 - 6.1e-200 665.4 16.8 9.4e-200 664.8 16.8 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Reovirus_M2 PF05993.12 KFP14354.1 - 0.072 11.2 0.0 0.12 10.4 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Flagellin_C PF00700.21 KFP14354.1 - 0.083 13.3 0.2 0.083 13.3 0.2 2.7 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF4363 PF14276.6 KFP14354.1 - 0.11 12.6 13.0 1.6 8.9 2.2 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) Sec8_exocyst PF04048.14 KFP14354.1 - 0.22 11.4 6.1 0.19 11.6 0.8 3.2 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain MitMem_reg PF13012.6 KFP14354.1 - 0.52 10.7 5.4 5.9 7.4 0.3 3.6 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function Ig_4 PF16680.5 KFP14355.1 - 2.1e-26 92.0 0.0 3.2e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP14355.1 - 1.5e-10 41.3 0.0 2.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ITAM PF02189.15 KFP14355.1 - 1.6e-06 28.2 1.5 2.8e-06 27.5 1.5 1.4 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif Izumo-Ig PF16706.5 KFP14355.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KFP14355.1 - 0.097 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_5 PF16681.5 KFP14356.1 - 6.7e-13 48.9 0.2 9.3e-13 48.4 0.2 1.2 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP14356.1 - 5.3e-09 36.2 0.4 7.4e-09 35.8 0.4 1.2 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain ITAM PF02189.15 KFP14356.1 - 0.0033 17.8 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif V-set PF07686.17 KFP14357.1 - 5.2e-23 81.3 0.2 8.7e-23 80.6 0.1 1.4 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFP14357.1 - 2.9e-08 33.8 0.3 6.1e-08 32.7 0.3 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP14357.1 - 4.3e-07 30.4 0.3 8.3e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP14357.1 - 3.9e-06 26.8 0.1 8.8e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP14357.1 - 5.3e-05 23.5 0.5 0.0024 18.2 0.5 2.2 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.6 KFP14357.1 - 0.027 15.3 0.1 0.044 14.7 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFP14357.1 - 0.035 14.0 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.19 KFP14357.1 - 1.5 8.7 8.7 0.054 13.3 2.7 1.7 2 1 0 2 2 2 0 Vpu protein V-set PF07686.17 KFP14358.1 - 3.3e-15 56.2 0.0 4.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP14358.1 - 1.3e-06 28.4 0.0 3.7e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP14358.1 - 0.0003 21.3 0.0 0.00071 20.1 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP14358.1 - 0.041 14.2 0.0 0.78 10.1 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP14358.1 - 0.15 12.2 0.0 0.44 10.6 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP14359.1 - 1.6e-12 47.5 0.2 2.2e-11 43.9 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP14359.1 - 0.00048 19.6 0.1 0.0023 17.5 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP14359.1 - 0.0076 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP14359.1 - 0.026 15.1 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain DUF4381 PF14316.6 KFP14359.1 - 0.043 14.0 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) I-set PF07679.16 KFP14359.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP14360.1 - 1.9e-21 76.2 0.3 3.5e-21 75.4 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP14360.1 - 5.3e-07 29.7 0.7 5.3e-07 29.7 0.7 2.1 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP14360.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP14360.1 - 7.3e-05 23.3 0.7 0.0003 21.3 0.7 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP14360.1 - 0.00023 21.4 3.3 0.0014 18.9 3.3 2.0 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.6 KFP14360.1 - 0.0033 18.3 0.0 0.0059 17.5 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KFP14360.1 - 0.0077 16.1 0.0 0.065 13.2 0.0 2.3 2 0 0 2 2 2 1 Syndecan domain PALP PF00291.25 KFP14360.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TMEM51 PF15345.6 KFP14360.1 - 0.058 13.2 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Adeno_E3_CR2 PF02439.15 KFP14360.1 - 0.062 13.1 0.3 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAM176 PF14851.6 KFP14360.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family COX14 PF14880.6 KFP14360.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Ig_4 PF16680.5 KFP14360.1 - 0.21 11.8 8.1 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Trypsin PF00089.26 KFP14361.1 - 2.7e-49 168.0 0.0 4.1e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFP14361.1 - 2.9e-13 50.2 2.7 6.8e-11 42.6 0.1 2.5 1 1 1 2 2 2 2 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 KFP14361.1 - 4.2e-07 30.4 0.0 6.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KFP14361.1 - 9.4e-07 29.8 0.0 1.4e-06 29.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Hepsin-SRCR PF09272.10 KFP14361.1 - 4.3e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 Hepsin, SRCR domain SRCR PF00530.18 KFP14361.1 - 0.00087 19.8 0.1 0.002 18.6 0.1 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Tissue_fac PF01108.17 KFP14362.1 - 8.3e-22 77.1 0.0 2e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP14362.1 - 2.1e-06 28.0 1.1 3.6e-06 27.2 0.2 1.8 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP14362.1 - 1.8e-05 25.0 0.6 0.0045 17.3 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain IQ PF00612.27 KFP14363.1 - 0.00011 21.7 0.8 0.00023 20.7 0.8 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif WW PF00397.26 KFP14365.1 - 1.5e-09 37.7 0.4 2.3e-09 37.1 0.4 1.3 1 0 0 1 1 1 1 WW domain Asp PF00026.23 KFP14366.1 - 5.8e-24 85.1 0.0 6.2e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFP14366.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_S8 PF00082.22 KFP14367.1 - 9.4e-44 149.8 0.8 1.3e-43 149.4 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFP14367.1 - 2.3e-27 94.8 0.0 5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFP14367.1 - 6e-16 59.0 0.2 1.2e-15 58.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KFP14367.1 - 0.00088 19.8 0.2 0.0019 18.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal of Subtilase family Lipase_GDSL_2 PF13472.6 KFP14368.1 - 7.7e-16 59.0 0.0 1.1e-15 58.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFP14368.1 - 0.0014 18.7 0.0 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFP14368.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Apolipoprotein PF01442.18 KFP14369.1 - 8.3e-48 162.8 13.1 9.7e-48 162.6 13.1 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KFP14369.1 - 7.2e-09 36.1 5.1 0.02 15.4 2.9 4.3 1 1 2 3 3 3 1 YtxH-like protein DUF883 PF05957.13 KFP14369.1 - 1.1e-06 29.1 9.0 0.28 11.8 1.4 4.0 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KFP14369.1 - 4.4e-05 23.6 1.3 0.3 11.4 0.0 4.1 1 1 3 4 4 4 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KFP14369.1 - 6.1e-05 23.1 0.6 1.1 9.3 0.1 3.1 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KFP14369.1 - 0.00018 21.6 4.8 0.015 15.4 1.4 3.0 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KFP14369.1 - 0.00022 19.4 1.2 0.029 12.4 0.6 2.0 1 1 1 2 2 2 2 Prominin ApoO PF09769.9 KFP14369.1 - 0.00079 19.4 0.9 0.85 9.6 0.3 3.6 1 1 1 2 2 2 1 Apolipoprotein O DUF4456 PF14644.6 KFP14369.1 - 0.00098 18.9 4.3 0.00098 18.9 4.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4456) Exonuc_VII_L PF02601.15 KFP14369.1 - 0.0016 18.1 4.9 0.0023 17.6 4.9 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF5063 PF16702.5 KFP14369.1 - 0.0029 18.0 1.3 0.22 11.9 0.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5063) GldM_N PF12081.8 KFP14369.1 - 0.0029 17.7 2.0 0.42 10.7 0.8 3.1 1 1 2 3 3 3 1 GldM N-terminal domain RRF PF01765.19 KFP14369.1 - 0.0047 16.9 4.7 0.086 12.8 0.2 2.4 1 1 1 2 2 2 1 Ribosome recycling factor ApoA-II PF04711.13 KFP14369.1 - 0.0084 16.2 4.4 0.094 12.9 0.1 3.2 1 1 0 2 2 2 1 Apolipoprotein A-II (ApoA-II) DUF1451 PF07295.11 KFP14369.1 - 0.0085 16.1 7.1 0.054 13.5 1.8 2.5 1 1 1 2 2 2 1 Zinc-ribbon containing domain DUF668 PF05003.12 KFP14369.1 - 0.0086 16.5 4.2 0.23 11.9 0.3 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF668) BORCS6 PF10157.9 KFP14369.1 - 0.011 16.0 0.0 0.73 10.0 0.0 2.5 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 Gp49 PF05973.14 KFP14369.1 - 0.011 15.8 4.2 1.7 8.8 0.2 3.4 2 1 1 3 3 3 0 Phage derived protein Gp49-like (DUF891) KMP11 PF03037.16 KFP14369.1 - 0.013 16.3 4.7 1.5 9.6 0.3 3.2 1 1 1 3 3 3 0 Kinetoplastid membrane protein 11 Cas_DxTHG PF09455.10 KFP14369.1 - 0.024 14.2 7.7 0.11 12.0 5.8 2.0 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family QIL1 PF15884.5 KFP14369.1 - 0.025 15.2 4.0 28 5.4 0.0 4.5 1 1 3 4 4 4 0 MICOS complex subunit MIC13, QIL1 DUF2937 PF11157.8 KFP14369.1 - 0.026 14.2 1.9 0.66 9.7 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) PIN_8 PF18476.1 KFP14369.1 - 0.027 14.3 5.2 0.11 12.3 3.5 2.0 1 1 1 2 2 2 0 PIN like domain Atg14 PF10186.9 KFP14369.1 - 0.031 13.4 4.3 0.039 13.0 4.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APP_E2 PF12925.7 KFP14369.1 - 0.035 13.8 8.9 0.53 10.0 0.1 2.9 1 1 2 3 3 3 0 E2 domain of amyloid precursor protein CHASE6_C PF17150.4 KFP14369.1 - 0.036 14.7 3.5 5.8 7.7 0.3 3.0 1 1 1 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain BshC PF10079.9 KFP14369.1 - 0.042 12.6 9.7 0.054 12.2 6.5 2.0 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC VirE PF05272.11 KFP14369.1 - 0.046 13.4 2.8 0.17 11.6 0.3 2.4 1 1 2 3 3 3 0 Virulence-associated protein E DUF445 PF04286.12 KFP14369.1 - 0.048 13.5 3.8 0.37 10.5 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) BAG6 PF12057.8 KFP14369.1 - 0.055 13.1 3.8 31 4.3 0.0 4.1 2 1 3 5 5 5 0 BCL2-associated athanogene 6 TPD52 PF04201.15 KFP14369.1 - 0.059 13.0 6.2 0.95 9.1 1.9 2.5 1 1 1 2 2 2 0 Tumour protein D52 family NPV_P10 PF05531.12 KFP14369.1 - 0.077 13.5 4.2 0.59 10.6 1.5 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4015 PF13200.6 KFP14369.1 - 0.082 12.0 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain 4HB_MCP_1 PF12729.7 KFP14369.1 - 0.097 12.2 5.0 0.14 11.7 3.6 1.9 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction TPR_MLP1_2 PF07926.12 KFP14369.1 - 0.1 12.7 13.3 0.15 12.1 4.8 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TipAS PF07739.13 KFP14369.1 - 0.11 13.0 6.5 2.8 8.5 6.0 2.9 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF1640 PF07798.11 KFP14369.1 - 0.12 12.4 7.5 6.5 6.8 7.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) FtsK_SpoIIIE PF01580.18 KFP14369.1 - 0.12 11.7 0.6 6.6 6.0 0.2 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family FAM184 PF15665.5 KFP14369.1 - 0.16 11.8 11.9 2.3 7.9 7.0 2.6 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B RapH_N PF18801.1 KFP14369.1 - 0.17 12.0 4.1 1.4 9.1 0.2 3.2 3 1 1 4 4 4 0 response regulator aspartate phosphatase H, N terminal HD_4 PF13328.6 KFP14369.1 - 0.17 11.6 2.0 1.5 8.5 1.1 2.2 1 1 1 2 2 2 0 HD domain Glyco_H_20C_C PF18088.1 KFP14369.1 - 0.18 11.6 7.6 0.52 10.1 2.3 3.3 1 1 1 3 3 3 0 Glycoside Hydrolase 20C C-terminal domain OmpH PF03938.14 KFP14369.1 - 0.24 11.7 12.7 0.64 10.3 5.1 2.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) YojJ PF10372.9 KFP14369.1 - 0.3 11.2 7.7 4.4 7.5 0.1 4.0 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus RB_A PF01858.17 KFP14369.1 - 0.32 10.8 5.1 4.5 7.1 0.2 3.0 1 1 2 3 3 3 0 Retinoblastoma-associated protein A domain Erp_C PF06780.11 KFP14369.1 - 0.33 11.0 5.7 2.3 8.2 0.2 2.5 2 1 0 2 2 2 0 Erp protein C-terminus DUF1043 PF06295.12 KFP14369.1 - 0.33 10.9 10.7 0.47 10.5 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) Ku_C PF03730.14 KFP14369.1 - 0.34 11.6 12.1 0.86 10.3 0.1 3.7 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Atypical_Card PF18461.1 KFP14369.1 - 0.35 11.1 3.5 2.6 8.3 0.7 2.6 2 1 0 2 2 2 0 Atypical caspase recruitment domain DUF1690 PF07956.11 KFP14369.1 - 0.41 11.1 10.3 1 9.8 2.6 3.1 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) TetR_C_37 PF18665.1 KFP14369.1 - 0.43 11.2 4.7 3.8 8.2 0.1 3.4 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain OTU PF02338.19 KFP14369.1 - 0.45 11.0 2.7 22 5.5 0.4 3.1 1 1 0 2 2 2 0 OTU-like cysteine protease Peptidase_S46 PF10459.9 KFP14369.1 - 0.63 8.6 5.0 0.69 8.5 5.0 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2203 PF09969.9 KFP14369.1 - 0.93 10.2 6.9 20 5.9 3.3 3.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4735 PF15882.5 KFP14369.1 - 1 8.7 3.0 5.9 6.2 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) FUSC PF04632.12 KFP14369.1 - 1.2 7.5 5.2 3.1 6.2 5.2 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 KFP14369.1 - 1.3 8.6 5.8 8 6.0 2.9 2.8 1 1 1 2 2 2 0 fzo-like conserved region 7TMR-HDED PF07697.11 KFP14369.1 - 1.4 9.0 7.4 3.7 7.6 7.4 1.8 1 1 0 1 1 1 0 7TM-HD extracellular Phe_tRNA-synt_N PF02912.18 KFP14369.1 - 1.7 8.6 7.1 3.7 7.5 0.1 3.6 3 1 2 5 5 4 0 Aminoacyl tRNA synthetase class II, N-terminal domain Matrilin_ccoil PF10393.9 KFP14369.1 - 1.7 8.5 6.6 29 4.6 0.2 3.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3106 PF11304.8 KFP14369.1 - 1.8 9.1 12.1 1 9.9 5.6 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF3106) Snapin_Pallidin PF14712.6 KFP14369.1 - 2.7 8.5 10.5 27 5.2 4.2 3.4 1 1 1 2 2 2 0 Snapin/Pallidin CENP-H PF05837.12 KFP14369.1 - 4.4 7.8 10.6 11 6.5 7.6 2.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Apolipoprotein PF01442.18 KFP14370.1 - 5.6e-33 114.4 0.0 9.4e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FliT PF05400.13 KFP14370.1 - 0.022 15.6 3.5 4.6 8.1 2.2 2.9 1 1 1 2 2 2 0 Flagellar protein FliT DUF1043 PF06295.12 KFP14370.1 - 0.024 14.7 0.6 0.11 12.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Dynamin_M PF01031.20 KFP14370.1 - 0.051 12.8 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Dynamin central region BAG6 PF12057.8 KFP14370.1 - 0.065 12.9 0.7 1.5 8.6 0.3 2.4 1 1 1 2 2 2 0 BCL2-associated athanogene 6 CorA PF01544.18 KFP14370.1 - 0.074 12.4 0.3 0.089 12.1 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein YtxH PF12732.7 KFP14370.1 - 0.075 13.6 0.0 0.28 11.7 0.0 2.0 1 1 0 1 1 1 0 YtxH-like protein AAA_22 PF13401.6 KFP14370.1 - 0.08 13.2 0.1 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 KFP14370.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4411 PF14367.6 KFP14370.1 - 0.19 11.6 0.0 0.53 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF883 PF05957.13 KFP14370.1 - 0.22 12.1 2.1 0.65 10.6 1.2 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-ZPR1 PF03367.13 KFP14371.1 - 5.9e-85 283.0 0.2 8e-56 188.3 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KFP14371.1 - 0.047 13.7 0.3 0.088 12.8 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KFP14371.1 - 0.097 12.8 0.3 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KFP14371.1 - 0.11 11.9 3.5 6.2 6.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.12 KFP14371.1 - 0.22 11.5 1.1 0.43 10.6 1.1 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Bud13 PF09736.9 KFP14372.1 - 1.7e-48 164.7 16.2 1.7e-48 164.7 16.2 2.6 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex I-set PF07679.16 KFP14373.1 - 2.1e-38 130.2 0.0 5.1e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP14373.1 - 9.1e-29 99.9 0.0 6.5e-13 49.1 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP14373.1 - 1.2e-18 67.2 0.1 1.9e-08 34.5 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP14373.1 - 1.5e-17 63.5 0.0 1.5e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain PH PF00169.29 KFP14373.1 - 5e-09 36.6 0.2 1.7e-08 34.9 0.2 2.0 1 0 0 1 1 1 1 PH domain C2-set_2 PF08205.12 KFP14373.1 - 1.4e-08 34.7 0.2 0.0019 18.2 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP14373.1 - 2.9e-07 30.7 0.2 0.073 13.3 0.1 4.6 2 2 0 2 2 2 2 Immunoglobulin V-set domain RhoGEF PF00621.20 KFP14373.1 - 0.0002 21.7 0.4 0.00045 20.5 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain BiPBP_C PF06832.12 KFP14373.1 - 0.00078 19.4 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family IQ_SEC7_PH PF16453.5 KFP14373.1 - 0.016 15.2 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 PH domain C1-set PF07654.15 KFP14373.1 - 0.095 13.1 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin C1-set domain DUF1722 PF08349.11 KFP14373.1 - 0.14 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Pkinase PF00069.25 KFP14374.1 - 2.7e-47 161.3 0.0 3.3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14374.1 - 6e-28 97.8 0.0 7.4e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14374.1 - 0.00088 18.7 0.1 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFP14374.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HIG_1_N PF04588.13 KFP14375.1 - 1.8e-17 63.3 2.1 1.8e-17 63.3 2.1 1.5 1 1 0 1 1 1 1 Hypoxia induced protein conserved region DUF3848 PF12959.7 KFP14376.1 - 0.022 14.8 1.3 0.022 14.8 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3848) Pox_A_type_inc PF04508.12 KFP14376.1 - 0.032 14.1 9.3 1.1 9.2 0.0 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat MBOAT PF03062.19 KFP14377.1 - 2.1e-13 50.4 14.1 3.6e-13 49.6 14.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Kelch_1 PF01344.25 KFP14378.1 - 5e-35 118.8 0.0 4.8e-10 38.8 0.0 5.7 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 KFP14378.1 - 7e-35 119.6 1.5 1.6e-34 118.5 0.6 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP14378.1 - 6.4e-29 100.1 0.3 2.9e-28 98.0 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP14378.1 - 1.1e-28 98.5 0.0 1.6e-07 31.4 0.0 5.4 2 1 3 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP14378.1 - 8.1e-23 80.2 0.0 5.4e-07 29.5 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP14378.1 - 1.8e-17 63.2 0.1 7.7e-05 22.9 0.0 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP14378.1 - 1.4e-14 53.4 0.6 0.009 16.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KFP14378.1 - 2.4e-14 52.9 0.8 0.0025 17.8 0.1 5.0 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 KFP14378.1 - 0.00026 21.1 0.7 0.19 12.0 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3342) RNase_H2-Ydr279 PF09468.10 KFP14378.1 - 3.1 7.9 5.1 61 3.8 5.1 2.2 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain zf-C2H2 PF00096.26 KFP14379.1 - 4.2e-33 111.9 63.1 9.2e-06 25.8 1.5 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP14379.1 - 1.6e-27 94.7 67.0 1.5e-07 31.5 1.3 9.7 9 1 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP14379.1 - 3.4e-25 86.5 61.7 0.0001 22.9 0.7 9.5 9 0 0 9 9 9 8 C2H2-type zinc finger BTB PF00651.31 KFP14379.1 - 6.4e-23 81.1 1.3 1.2e-22 80.3 1.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.7 KFP14379.1 - 6.7e-09 35.8 49.9 0.0019 18.5 0.1 8.9 9 0 0 9 9 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP14379.1 - 3.2e-07 30.5 49.8 0.049 13.9 0.0 8.6 9 0 0 9 9 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP14379.1 - 3.2e-07 30.2 58.7 0.0082 16.1 0.2 9.5 9 0 0 9 9 9 5 C2H2-type zinc finger zf_UBZ PF18439.1 KFP14379.1 - 0.00041 19.9 33.9 1.2 8.7 0.1 9.1 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFP14379.1 - 0.0055 17.0 1.3 0.0055 17.0 1.3 5.0 4 2 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KFP14379.1 - 0.019 15.1 39.2 0.32 11.1 1.2 7.0 2 2 6 8 8 8 0 Zinc ribbon domain BolA PF01722.18 KFP14379.1 - 0.021 15.1 9.0 2.4 8.5 0.0 4.1 3 1 1 4 4 3 0 BolA-like protein zf-C2H2_2 PF12756.7 KFP14379.1 - 0.029 14.7 49.8 0.8 10.1 2.0 7.4 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP14379.1 - 0.059 14.1 33.8 0.78 10.4 0.1 6.9 1 1 4 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFP14379.1 - 0.16 11.8 0.1 0.11 12.2 0.6 7.3 8 0 0 8 8 7 0 zinc-finger C2H2-type zf-FCS PF06467.14 KFP14379.1 - 0.19 11.7 31.0 0.36 10.8 1.5 7.0 5 1 2 7 7 7 0 MYM-type Zinc finger with FCS sequence motif CDC45 PF02724.14 KFP14379.1 - 0.21 9.9 9.9 0.29 9.4 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-MYST PF17772.1 KFP14379.1 - 0.5 10.0 0.0 0.5 10.0 0.0 6.2 5 3 3 8 8 8 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFP14379.1 - 0.66 10.8 31.5 2.2 9.1 0.8 5.0 2 1 4 6 6 6 0 zinc-ribbon family SDA1 PF05285.12 KFP14379.1 - 0.79 9.1 16.4 1.2 8.5 16.4 1.2 1 0 0 1 1 1 0 SDA1 zf-C2H2_8 PF15909.5 KFP14379.1 - 0.8 10.0 33.8 0.37 11.1 6.4 4.4 1 1 1 4 4 4 0 C2H2-type zinc ribbon DUF3268 PF11672.8 KFP14379.1 - 0.93 9.8 17.8 1.2 9.5 0.8 4.3 3 1 1 4 4 4 0 zinc-finger-containing domain Nop14 PF04147.12 KFP14379.1 - 2.9 6.0 18.9 4.3 5.4 18.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 KFP14379.1 - 3.1 7.2 10.9 4.5 6.6 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PGA2 PF07543.12 KFP14379.1 - 3.7 7.5 11.0 8.6 6.3 11.0 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 zf-C2HC_2 PF13913.6 KFP14379.1 - 5.3 7.1 49.5 0.76 9.7 0.4 8.8 9 0 0 9 9 9 0 zinc-finger of a C2HC-type Cript PF10235.9 KFP14379.1 - 6.4 7.4 36.1 0.15 12.7 2.6 5.5 3 1 2 5 5 4 0 Microtubule-associated protein CRIPT ADK_lid PF05191.14 KFP14379.1 - 7.8 6.6 31.6 0.65 10.0 1.0 5.4 5 1 1 6 6 5 0 Adenylate kinase, active site lid Pro_isomerase PF00160.21 KFP14380.1 - 1.5e-46 158.6 0.1 3.8e-46 157.2 0.1 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 KFP14380.1 - 0.0002 21.0 25.2 0.0002 21.0 25.2 10.1 4 3 4 8 8 8 1 Nuclear RNA-splicing-associated protein Cadherin PF00028.17 KFP14381.1 - 0 1445.3 43.6 8e-21 74.3 0.0 27.4 27 0 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.12 KFP14381.1 - 8e-28 96.1 0.0 0.076 12.9 0.0 16.7 18 0 0 18 18 18 6 Cadherin-like Cadherin_3 PF16184.5 KFP14381.1 - 1.1e-19 70.4 37.4 0.0029 17.6 0.0 18.8 22 0 0 22 22 22 7 Cadherin-like RET_CLD1 PF17756.1 KFP14381.1 - 1.3e-11 44.8 0.0 2 8.7 0.0 9.9 11 0 0 11 11 11 2 RET Cadherin like domain 1 Cadherin_pro PF08758.11 KFP14381.1 - 1.1e-08 35.1 0.0 8 6.7 0.0 9.5 11 0 0 11 11 11 2 Cadherin prodomain like SusE PF14292.6 KFP14381.1 - 3.5 7.9 11.1 3.3 8.0 0.1 5.5 5 0 0 5 5 5 0 SusE outer membrane protein V-set PF07686.17 KFP14382.1 - 5.5e-06 26.5 0.3 7.1e-05 22.9 0.3 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP14382.1 - 9.5e-06 25.7 0.6 0.00028 21.0 0.6 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP14382.1 - 0.00012 22.6 0.2 0.0013 19.3 0.2 2.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP14382.1 - 0.00028 21.1 0.2 0.72 10.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP14382.1 - 0.051 13.6 0.0 4.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin I-set domain FAP PF07174.11 KFP14382.1 - 0.067 12.6 2.7 0.095 12.1 2.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SapB_1 PF05184.15 KFP14383.1 - 4.7e-44 147.9 25.0 1.3e-13 50.6 0.9 5.7 5 0 0 5 5 5 4 Saposin-like type B, region 1 SapB_2 PF03489.17 KFP14383.1 - 2.1e-42 142.9 47.6 1.1e-11 44.6 2.4 6.0 7 0 0 7 7 7 4 Saposin-like type B, region 2 SapA PF02199.15 KFP14383.1 - 9.4e-17 61.0 22.8 3.2e-16 59.3 9.5 4.0 3 0 0 3 3 3 2 Saposin A-type domain TLE_N PF03920.15 KFP14383.1 - 0.067 13.3 5.6 0.66 10.1 0.2 3.4 3 1 1 4 4 4 0 Groucho/TLE N-terminal Q-rich domain Mustang PF15682.5 KFP14383.1 - 0.1 12.7 0.3 0.32 11.1 0.1 1.9 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 DUF4451 PF14616.6 KFP14383.1 - 2.5 8.3 10.2 17 5.7 0.2 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4451) Pyr_redox_2 PF07992.14 KFP14384.1 - 2.9e-40 138.4 2.5 3.4e-40 138.1 2.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP14384.1 - 8.5e-10 39.1 4.5 6.8e-09 36.2 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP14384.1 - 3.7e-08 33.0 1.1 4.3e-08 32.8 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP14384.1 - 5.8e-08 32.2 0.0 1.2e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFP14384.1 - 6e-06 26.3 3.7 0.34 10.9 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 KFP14384.1 - 0.00083 19.0 7.0 0.18 11.3 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KFP14384.1 - 0.0017 17.1 0.5 0.24 10.1 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KFP14384.1 - 0.0037 17.4 2.0 2.7 8.3 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFP14384.1 - 0.0053 15.9 0.7 0.058 12.4 0.2 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 KFP14384.1 - 0.045 12.8 13.7 4.7 6.2 2.2 4.2 3 1 1 4 4 4 0 Glucose inhibited division protein A TrkA_N PF02254.18 KFP14384.1 - 0.051 13.8 0.3 11 6.3 0.1 2.8 3 0 0 3 3 3 0 TrkA-N domain DUF4147 PF13660.6 KFP14384.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) FAD_binding_3 PF01494.19 KFP14384.1 - 0.17 11.1 2.0 1.2 8.4 0.5 2.2 2 0 0 2 2 2 0 FAD binding domain AvrPto PF11592.8 KFP14384.1 - 0.17 11.9 0.0 27 4.8 0.0 2.5 2 0 0 2 2 2 0 Central core of the bacterial effector protein AvrPto NAD_binding_7 PF13241.6 KFP14384.1 - 0.25 11.8 1.4 0.36 11.3 0.3 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KFP14384.1 - 0.6 9.3 4.4 0.25 10.5 0.2 2.3 2 1 1 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 KFP14384.1 - 0.69 8.7 6.0 1 8.1 0.3 2.9 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KFP14384.1 - 2.5 7.1 7.1 3.3 6.7 0.1 2.9 3 0 0 3 3 3 0 FAD binding domain Macro PF01661.21 KFP14385.1 - 7.1e-27 93.8 0.1 1.3e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 KFP14385.1 - 1.6e-16 59.7 0.6 1.6e-16 59.7 0.6 2.6 3 0 0 3 3 3 1 C-terminus of histone H2A Histone PF00125.24 KFP14385.1 - 4.9e-13 49.6 6.1 4.5e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP14385.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.20 KFP14385.1 - 0.068 13.3 0.2 0.49 10.6 0.0 2.5 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component AAR2 PF05282.11 KFP14385.1 - 0.12 11.7 1.0 0.21 11.0 0.6 1.5 2 0 0 2 2 2 0 AAR2 protein DUF1764 PF08576.10 KFP14385.1 - 0.16 12.8 4.8 0.4 11.6 4.8 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Tetraspanin PF00335.20 KFP14386.1 - 6.1e-49 166.8 7.6 7.4e-49 166.5 7.6 1.1 1 0 0 1 1 1 1 Tetraspanin family LMBR1 PF04791.16 KFP14386.1 - 0.021 13.8 1.0 0.021 13.7 0.4 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF2206 PF09971.9 KFP14386.1 - 1.1 8.0 5.5 1.7 7.3 5.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Hexokinase_2 PF03727.16 KFP14388.1 - 2.4e-170 564.1 0.8 2.5e-86 289.0 0.2 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP14388.1 - 4.7e-141 467.3 0.2 3.3e-72 242.6 0.1 2.3 2 0 0 2 2 2 2 Hexokinase CSD PF00313.22 KFP14388.1 - 0.0035 17.2 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain GPS2_interact PF15784.5 KFP14388.1 - 0.14 12.6 0.8 10 6.7 0.1 2.5 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Hexokinase_2 PF03727.16 KFP14389.1 - 1.3e-169 561.6 1.2 1.5e-88 296.3 0.2 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP14389.1 - 2.1e-134 445.6 0.0 3.6e-70 235.9 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Suv3_N PF18114.1 KFP14390.1 - 1.5e-35 121.8 0.4 3.6e-35 120.6 0.4 1.7 1 0 0 1 1 1 1 Suv3 helical N-terminal domain Suv3_C_1 PF18147.1 KFP14390.1 - 5.8e-16 58.1 0.2 1.1e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 KFP14390.1 - 1.4e-15 57.0 0.1 3.4e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KFP14390.1 - 5e-11 42.9 0.0 1.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vps26 PF03643.15 KFP14391.1 - 2.3e-133 443.4 5.2 2.7e-133 443.1 5.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 KFP14391.1 - 0.0011 19.5 0.2 0.02 15.4 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFP14391.1 - 0.013 15.5 0.3 0.45 10.6 0.0 3.0 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Serglycin PF04360.12 KFP14392.1 - 1.6e-26 93.0 0.0 1.6e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Serglycin KBP_C PF12309.8 KFP14393.1 - 3e-128 428.3 11.1 3e-128 428.3 11.1 2.2 2 0 0 2 2 2 1 KIF-1 binding protein C terminal AbiJ_NTD5 PF18865.1 KFP14393.1 - 0.01 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 TPR_1 PF00515.28 KFP14393.1 - 0.044 13.6 0.5 0.044 13.6 0.5 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP14393.1 - 0.062 13.4 11.4 1.8 8.8 0.6 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat RGS PF00615.19 KFP14393.1 - 0.13 12.6 0.3 0.13 12.6 0.3 2.7 3 0 0 3 3 3 0 Regulator of G protein signaling domain TPR_12 PF13424.6 KFP14393.1 - 0.5 10.7 11.8 1 9.7 1.6 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat GUCT PF08152.12 KFP14394.1 - 2.8e-32 110.9 0.0 9.4e-32 109.2 0.0 1.9 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.31 KFP14394.1 - 3.2e-25 88.6 0.0 7.6e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFP14394.1 - 0.0034 16.6 0.0 0.0074 15.5 0.0 1.5 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 KFP14395.1 - 9e-26 90.4 0.0 3.5e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 KFP14395.1 - 9.4e-17 61.1 0.0 1.9e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 KFP14395.1 - 0.0036 16.5 0.0 0.014 14.7 0.0 1.8 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Stork_head PF10264.9 KFP14396.1 - 3.8e-32 110.3 0.1 9.3e-32 109.0 0.1 1.7 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Tet_JBP PF12851.7 KFP14397.1 - 5.2e-74 249.6 0.0 5.2e-74 249.6 0.0 2.7 2 1 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily zf-CXXC PF02008.20 KFP14397.1 - 7.3e-05 22.7 28.8 7.3e-05 22.7 28.8 2.6 2 0 0 2 2 2 1 CXXC zinc finger domain Mito_carr PF00153.27 KFP14398.1 - 5.3e-68 225.0 6.7 3.9e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP14398.1 - 0.0001 21.6 1.3 0.015 14.5 0.1 2.8 2 2 0 2 2 2 2 Gammaproteobacterial serine protease Dna2 PF08696.11 KFP14399.1 - 6.3e-62 209.0 0.1 1.5e-61 207.8 0.1 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KFP14399.1 - 1.5e-47 161.8 4.9 1.6e-31 109.5 0.2 3.0 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 KFP14399.1 - 6.4e-27 95.0 0.7 1.3e-17 64.5 0.1 2.9 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KFP14399.1 - 8.9e-11 41.9 0.0 9.8e-10 38.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KFP14399.1 - 2.6e-09 37.4 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KFP14399.1 - 2.8e-09 37.1 0.3 0.0031 17.3 0.0 3.6 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KFP14399.1 - 4.4e-07 30.3 0.1 4e-05 24.0 0.2 3.0 2 1 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.17 KFP14399.1 - 0.00036 20.7 9.1 0.01 16.0 0.8 3.7 3 1 0 3 3 3 2 Domain of unknown function DUF83 AAA_25 PF13481.6 KFP14399.1 - 0.00095 18.8 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFP14399.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFP14399.1 - 0.0073 15.8 0.0 0.036 13.5 0.0 2.3 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KFP14399.1 - 0.017 15.5 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KFP14399.1 - 0.026 15.0 0.6 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KFP14399.1 - 0.031 14.3 0.2 0.32 11.0 0.1 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KFP14399.1 - 0.042 13.4 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFP14399.1 - 0.13 12.8 0.0 0.5 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KFP14399.1 - 0.15 11.6 0.9 2 7.8 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 KFP14399.1 - 0.18 12.0 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFP14399.1 - 0.19 11.4 0.1 0.48 10.0 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GerD PF17898.1 KFP14399.1 - 2.4 8.1 5.7 2 8.4 1.7 2.5 2 1 0 2 2 2 0 Spore germination GerD central core domain RUN PF02759.19 KFP14401.1 - 3.9e-29 101.3 0.2 7.8e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 RUN domain Trimer_CC PF08954.11 KFP14401.1 - 0.011 15.3 0.2 0.23 11.0 0.0 2.5 2 0 0 2 2 2 0 Trimerisation motif ATG16 PF08614.11 KFP14401.1 - 0.11 12.7 20.2 0.15 12.3 20.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CASP_C PF08172.12 KFP14401.1 - 0.12 11.6 13.7 1.1 8.5 4.6 2.8 2 1 1 3 3 3 0 CASP C terminal COG2 PF06148.11 KFP14401.1 - 0.33 11.0 16.8 0.057 13.5 9.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KFP14401.1 - 1 9.6 6.0 43 4.5 1.8 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Nnf1 PF03980.14 KFP14401.1 - 1.1 9.6 14.8 0.98 9.8 0.1 3.2 2 1 0 2 2 2 0 Nnf1 SlyX PF04102.12 KFP14401.1 - 1.2 9.8 14.8 2.7 8.7 5.1 3.2 2 2 0 2 2 2 0 SlyX Spc7 PF08317.11 KFP14401.1 - 2.9 6.7 23.8 2.1 7.1 11.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.13 KFP14401.1 - 5.5 7.1 21.1 3.7e+03 -2.1 21.1 2.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RRM_1 PF00076.22 KFP14402.1 - 1.1e-21 76.4 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhzC-PhzF PF02567.16 KFP14403.1 - 2e-60 204.7 0.0 2.4e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HLH PF00010.26 KFP14404.1 - 1.2e-18 66.8 0.1 1.7e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DERM PF14704.6 KFP14404.1 - 0.096 13.2 0.2 1.3 9.5 0.1 2.1 1 1 1 2 2 2 0 Dermatopontin DUF1295 PF06966.12 KFP14404.1 - 0.1 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) SIR2 PF02146.17 KFP14405.1 - 2.5e-63 213.2 0.0 4.2e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFP14405.1 - 0.0011 18.7 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KFP14405.1 - 0.0059 16.4 0.2 0.01 15.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) DnaJ PF00226.31 KFP14406.1 - 2e-19 69.5 0.4 4.4e-19 68.4 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain Vinculin PF01044.19 KFP14407.1 - 1e-43 149.8 1.6 1.1e-43 149.7 1.6 1.0 1 0 0 1 1 1 1 Vinculin family HTH_57 PF18679.1 KFP14407.1 - 0.019 15.3 0.5 0.055 13.8 0.1 1.9 2 0 0 2 2 2 0 ThcOx helix turn helix domain PilJ PF13675.6 KFP14407.1 - 0.032 14.2 1.7 0.69 9.9 0.2 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMEM89 PF15098.6 KFP14407.1 - 0.1 12.7 0.2 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 TMEM89 protein family LRR_8 PF13855.6 KFP14408.1 - 8.1e-55 182.4 60.8 2.4e-14 52.8 5.6 5.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 KFP14408.1 - 2.1e-31 108.5 1.5 7.5e-13 48.6 0.2 3.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP14408.1 - 4.8e-19 68.2 39.5 5.5e-05 23.5 3.3 6.5 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP14408.1 - 4.1e-10 39.4 7.6 0.00015 21.3 3.2 3.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFP14408.1 - 7.6e-07 28.8 39.2 1.2 9.9 0.6 10.6 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP14408.1 - 6.9e-06 25.7 30.7 1.1 9.5 0.2 9.6 10 0 0 10 10 10 2 Leucine Rich repeat LRRNT PF01462.18 KFP14408.1 - 3e-05 23.6 0.6 3e-05 23.6 0.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain EphA2_TM PF14575.6 KFP14408.1 - 0.12 13.3 0.2 0.33 11.8 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_2 PF07723.13 KFP14408.1 - 6.1 7.7 12.7 10 7.0 0.2 6.3 7 1 1 8 8 8 0 Leucine Rich Repeat TB2_DP1_HVA22 PF03134.19 KFP14412.1 - 3.8e-27 94.0 10.1 5.9e-27 93.4 10.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.9 KFP14412.1 - 0.059 13.6 0.8 0.1 12.8 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) NRBF2 PF08961.10 KFP14413.1 - 1e-101 338.6 7.0 1e-101 338.6 7.0 1.4 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator NRBF2_MIT PF17169.4 KFP14413.1 - 2.3e-45 152.7 11.1 2.3e-45 152.7 11.1 1.7 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 DivIC PF04977.15 KFP14413.1 - 0.00035 20.3 3.2 0.00035 20.3 3.2 2.2 2 1 0 2 2 2 1 Septum formation initiator YabA PF06156.13 KFP14413.1 - 0.00066 20.3 9.5 0.00099 19.7 0.9 2.2 2 0 0 2 2 2 1 Initiation control protein YabA MIT PF04212.18 KFP14413.1 - 0.001 19.1 6.1 0.0027 17.8 6.0 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain PikAIV_N PF18605.1 KFP14413.1 - 0.0033 17.0 3.6 0.0069 15.9 3.6 1.6 1 0 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 KFP14413.1 - 0.0056 17.1 2.4 0.0056 17.1 2.4 2.5 2 1 1 3 3 2 1 Cell division protein ZapB TSC22 PF01166.18 KFP14413.1 - 0.02 15.2 0.8 0.054 13.8 0.8 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family CtIP_N PF10482.9 KFP14413.1 - 0.042 13.9 0.6 0.042 13.9 0.6 2.6 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF5101 PF17031.5 KFP14413.1 - 0.079 13.1 1.0 0.079 13.1 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) TPR_7 PF13176.6 KFP14413.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ERM PF00769.19 KFP14416.1 - 0.0053 16.6 15.6 0.0068 16.3 15.6 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family RBD-FIP PF09457.10 KFP14416.1 - 0.012 15.5 2.7 0.061 13.3 2.7 2.1 1 1 0 1 1 1 0 FIP domain Chal_sti_synt_N PF00195.19 KFP14416.1 - 0.043 13.2 1.2 0.087 12.2 0.7 1.6 1 1 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Ku_PK_bind PF08785.11 KFP14416.1 - 0.048 13.8 4.5 0.83 9.8 4.5 2.2 1 1 0 1 1 1 0 Ku C terminal domain like VPS53_C PF16854.5 KFP14416.1 - 0.11 12.3 2.4 0.17 11.7 2.4 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus FUSC PF04632.12 KFP14416.1 - 0.13 10.8 7.8 0.17 10.4 7.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family BAF250_C PF12031.8 KFP14416.1 - 0.27 10.5 3.0 0.24 10.7 1.6 1.6 1 1 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa FapA PF03961.13 KFP14416.1 - 0.43 9.1 9.5 0.51 8.9 8.9 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A PMC2NT PF08066.12 KFP14416.1 - 0.49 11.1 3.7 12 6.6 0.0 3.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF641 PF04859.12 KFP14416.1 - 0.53 10.6 13.4 0.61 10.4 3.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Nipped-B_C PF12830.7 KFP14416.1 - 0.56 10.1 6.7 1.1 9.1 6.7 1.5 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus Spc7 PF08317.11 KFP14416.1 - 0.62 8.9 15.8 0.9 8.4 15.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-Q PF13094.6 KFP14416.1 - 1 9.5 18.2 0.3 11.3 9.3 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC-like PF12805.7 KFP14416.1 - 1.2 8.1 4.9 0.6 9.1 2.4 1.6 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS dCache_2 PF08269.11 KFP14416.1 - 1.4 8.0 9.9 0.31 10.2 5.9 1.8 1 1 1 2 2 2 0 Cache domain LMBR1 PF04791.16 KFP14416.1 - 1.4 7.7 4.3 1.9 7.3 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 KFP14416.1 - 1.5 8.3 14.5 4.2 6.8 14.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit ALS2CR8 PF15299.6 KFP14416.1 - 1.6 8.5 8.1 1.8 8.4 2.4 2.3 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 V_ATPase_I PF01496.19 KFP14416.1 - 2.2 6.1 7.7 2.9 5.7 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 KFP14416.1 - 5.1 7.5 14.7 4.7 7.7 10.0 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UPF0449 PF15136.6 KFP14416.1 - 5.3 7.6 9.0 3.3e+02 1.8 9.0 2.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 COG2 PF06148.11 KFP14416.1 - 5.6 7.0 11.2 21 5.2 9.2 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 KFP14416.1 - 7.2 6.7 24.5 1.2 9.3 15.5 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CDC37_N PF03234.14 KFP14416.1 - 8.9 7.2 9.0 66 4.4 9.0 2.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding ZapB PF06005.12 KFP14416.1 - 9.9 6.7 21.0 0.68 10.4 4.5 2.6 2 1 1 3 3 2 0 Cell division protein ZapB Anillin PF08174.11 KFP14417.1 - 1.1e-46 158.8 1.1 1.4e-46 158.4 0.1 1.8 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 KFP14417.1 - 9.1e-08 32.6 0.8 3.3e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KFP14417.1 - 0.0055 17.1 0.0 0.019 15.4 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain HR1 PF02185.16 KFP14417.1 - 0.0081 16.3 0.7 0.027 14.6 0.7 1.9 1 0 0 1 1 1 1 Hr1 repeat ARID PF01388.21 KFP14418.1 - 6.5e-17 62.0 0.0 1.6e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CLAMP PF14769.6 KFP14419.1 - 5.8e-23 81.2 0.0 7.8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Sad1_UNC PF07738.13 KFP14419.1 - 0.012 15.6 0.0 0.092 12.8 0.0 1.9 1 1 0 1 1 1 0 Sad1 / UNC-like C-terminal Tmem26 PF09772.9 KFP14420.1 - 1.3e-100 336.5 6.8 1.5e-100 336.3 6.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 BTB PF00651.31 KFP14421.1 - 2.7e-29 101.6 5.7 4e-17 62.5 0.1 3.9 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.22 KFP14421.1 - 1.3e-23 83.4 0.0 2.5e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14421.1 - 7.4e-11 42.3 0.0 1.9e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF1154 PF06631.11 KFP14421.1 - 0.39 10.8 2.2 1.3 9.1 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) BACK PF07707.15 KFP14421.1 - 1 9.5 4.8 1.8 8.7 0.2 3.1 3 1 0 3 3 3 0 BTB And C-terminal Kelch Ank_2 PF12796.7 KFP14424.1 - 2e-142 464.1 45.8 1.4e-15 57.6 1.0 11.5 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 KFP14424.1 - 8.6e-130 418.1 63.3 2.7e-06 27.6 0.0 23.2 21 1 2 23 23 23 21 Ankyrin repeat Ank_4 PF13637.6 KFP14424.1 - 1.1e-125 408.5 55.5 7.6e-11 42.3 0.3 17.1 3 2 16 20 20 20 20 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP14424.1 - 2.5e-118 384.6 32.6 2.6e-11 43.5 0.0 15.3 4 4 12 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP14424.1 - 1.9e-107 338.0 30.4 0.00013 22.1 0.0 23.6 23 0 0 23 23 23 20 Ankyrin repeat UPA_2 PF17809.1 KFP14424.1 - 2.3e-52 176.3 0.6 6.7e-52 174.8 0.0 2.3 2 0 0 2 2 2 1 UPA domain ZU5 PF00791.20 KFP14424.1 - 2.5e-33 114.3 0.9 8.5e-27 93.4 0.0 3.0 2 0 0 2 2 2 2 ZU5 domain DUF1110 PF06533.12 KFP14424.1 - 0.081 12.9 0.9 0.36 10.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) Death PF00531.22 KFP14425.1 - 3.8e-21 75.1 0.0 7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Death domain PYC_OADA PF02436.18 KFP14425.1 - 0.011 15.5 0.4 0.03 14.1 0.4 1.7 1 0 0 1 1 1 0 Conserved carboxylase domain ubiquitin PF00240.23 KFP14425.1 - 0.041 13.6 0.0 0.83 9.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin family DUF2533 PF10752.9 KFP14425.1 - 0.11 13.0 0.4 3.9 8.0 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) DUF2046 PF09755.9 KFP14426.1 - 5.4e-120 400.2 49.7 6.4e-120 400.0 49.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 KFP14426.1 - 4 7.6 45.9 0.59 10.3 20.5 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MFS_1 PF07690.16 KFP14427.1 - 1.3e-28 100.0 34.9 1.4e-16 60.4 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPW_gp25 PF04965.14 KFP14428.1 - 0.088 12.6 0.4 0.78 9.5 0.0 2.6 3 0 0 3 3 3 0 Gene 25-like lysozyme PilO PF04350.13 KFP14428.1 - 0.38 10.9 4.8 0.16 12.1 0.8 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilO Spectrin PF00435.21 KFP14428.1 - 1.3 9.5 6.8 0.56 10.7 2.5 2.7 2 0 0 2 2 2 0 Spectrin repeat PilJ PF13675.6 KFP14428.1 - 1.9 8.5 4.3 38 4.4 0.1 3.1 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term fn3 PF00041.21 KFP14429.1 - 1.4e-07 31.8 0.2 5.2e-07 29.9 0.1 2.0 2 1 0 2 2 2 1 Fibronectin type III domain fn3_4 PF16794.5 KFP14429.1 - 0.0083 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin-III type domain KH_1 PF00013.29 KFP14430.1 - 2.8e-37 126.3 5.4 1.9e-15 56.4 0.4 5.7 6 0 0 6 6 6 3 KH domain SAM_1 PF00536.30 KFP14430.1 - 2.7e-14 53.3 0.1 5.6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP14430.1 - 4.4e-11 42.7 0.1 1.1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KH_10 PF17905.1 KFP14430.1 - 6.8e-09 36.0 0.2 0.0031 17.9 0.0 3.7 3 0 0 3 3 3 2 GLD-3 KH domain 5 KH_2 PF07650.17 KFP14430.1 - 0.0003 20.5 0.1 0.12 12.2 0.2 2.7 2 0 0 2 2 2 2 KH domain SLS PF14611.6 KFP14430.1 - 0.0013 18.6 1.4 1.7 8.4 0.3 4.0 2 1 2 4 4 4 2 Mitochondrial inner-membrane-bound regulator Alanine_zipper PF11839.8 KFP14430.1 - 0.11 12.9 4.6 0.29 11.5 4.6 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein IGR PF09597.10 KFP14430.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 IGR protein motif DUF2369 PF10179.9 KFP14431.1 - 1.2e-35 121.7 1.5 1.4e-32 111.9 0.4 3.5 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KFP14431.1 - 6.8e-08 32.8 2.4 0.003 17.9 0.1 4.6 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP14431.1 - 0.0013 19.2 3.9 0.12 12.9 0.1 3.3 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain CopK PF11525.8 KFP14431.1 - 0.068 12.8 0.3 17 5.1 0.1 2.8 3 0 0 3 3 3 0 Copper resistance protein K Interfer-bind PF09294.10 KFP14431.1 - 6 7.2 6.6 4.9 7.5 0.0 4.0 5 1 0 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III Nebulin PF00880.18 KFP14438.1 - 5.3e-22 77.3 2.7 1.6e-10 40.7 0.3 2.6 2 0 0 2 2 2 2 Nebulin repeat LIM PF00412.22 KFP14438.1 - 3.9e-07 30.2 7.4 3.9e-07 30.2 7.4 1.8 2 0 0 2 2 2 1 LIM domain SH3_1 PF00018.28 KFP14438.1 - 3e-06 26.7 0.2 5.7e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP14438.1 - 0.00061 19.6 0.1 0.00099 18.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP14438.1 - 0.019 14.6 0.0 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain Ribosomal_L14 PF00238.19 KFP14439.1 - 7.4e-25 87.4 0.0 7.9e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 KFP14439.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal CWC25 PF12542.8 KFP14440.1 - 2e-21 76.8 0.0 2e-21 76.8 0.0 4.7 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFP14440.1 - 1.6e-15 57.0 13.8 1.6e-15 57.0 13.8 6.4 6 1 1 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR PIP5K PF01504.18 KFP14441.1 - 2e-76 256.8 0.1 2.8e-76 256.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Proteasome PF00227.26 KFP14442.1 - 8.4e-29 100.4 0.0 9.4e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MICSWaP PF17018.5 KFP14442.1 - 0.033 13.7 0.0 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Spore wall protein DUF676 PF05057.14 KFP14450.1 - 1.3e-57 194.9 0.0 2.2e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KFP14450.1 - 5.1e-19 68.6 2.8 2.6e-18 66.3 1.2 2.8 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KFP14450.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFP14450.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFP14450.1 - 0.0068 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DIRP PF06584.13 KFP14450.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 DIRP Il13Ra_Ig PF18001.1 KFP14450.1 - 0.2 11.8 3.1 8.9 6.5 0.0 4.1 4 0 0 4 4 4 0 Interleukin-13 receptor subunit alpha Ig-like domain RVT_1 PF00078.27 KFP14452.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP14456.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 KFP14460.1 - 9.2e-38 128.1 16.8 1.8e-18 66.3 8.7 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFP14460.1 - 1.5e-07 30.9 3.9 0.019 14.2 0.0 2.2 1 1 0 2 2 2 2 Ion transport protein CLTH PF10607.9 KFP14460.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain IRK PF01007.20 KFP14460.1 - 0.19 11.5 4.2 0.31 10.9 0.0 2.6 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain TRAPPC9-Trs120 PF08626.11 KFP14462.1 - 0.12 9.7 0.0 0.15 9.4 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 60KD_IMP PF02096.20 KFP14464.1 - 8.6e-13 48.5 0.0 1.4e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein HlyC PF02794.16 KFP14464.1 - 0.02 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 RTX toxin acyltransferase family Pep_M12B_propep PF01562.19 KFP14465.1 - 4e-32 111.4 0.0 8.2e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFP14465.1 - 4.5e-32 110.5 0.0 8.2e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP14465.1 - 7.1e-22 77.4 62.3 2.3e-10 40.5 6.0 6.3 6 0 0 6 6 6 4 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KFP14465.1 - 3.1e-21 75.7 20.0 5.5e-20 71.6 7.0 5.2 5 1 1 6 6 2 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP14465.1 - 4.7e-19 69.1 0.0 4.7e-19 69.1 0.0 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KFP14465.1 - 1.5e-13 51.3 0.6 3.5e-13 50.1 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP14465.1 - 1.2e-09 38.8 0.3 2.5e-09 37.7 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP14465.1 - 1.3e-09 38.2 0.3 2.5e-09 37.3 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP14465.1 - 1.6e-06 27.9 0.2 3.3e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFP14465.1 - 0.00044 20.9 5.6 0.00044 20.9 5.6 2.9 2 0 0 2 2 1 1 PLAC (protease and lacunin) domain Peptidase_M10 PF00413.24 KFP14465.1 - 0.001 18.9 0.1 0.0025 17.7 0.1 1.7 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 KFP14465.1 - 0.1 11.8 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Met-zincin FA_desaturase PF00487.24 KFP14466.1 - 5.7e-33 114.8 31.2 5.7e-33 114.8 31.2 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFP14467.1 - 7.1e-20 70.9 0.2 1.1e-19 70.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KFP14467.1 - 9.8e-13 48.5 4.2 9.8e-13 48.5 4.2 2.0 1 1 1 2 2 2 1 Fatty acid desaturase FA_desaturase PF00487.24 KFP14469.1 - 4.7e-32 111.8 25.1 4.7e-32 111.8 25.1 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Catalase PF00199.19 KFP14470.1 - 1.1e-195 650.2 0.0 1.4e-195 649.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFP14470.1 - 3.9e-20 71.8 1.0 1.1e-19 70.4 0.4 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive BTB PF00651.31 KFP14471.1 - 5.9e-24 84.4 0.5 1.5e-23 83.1 0.5 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 KFP14471.1 - 1.4e-20 73.7 0.0 2.5e-11 44.0 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP14471.1 - 3.4e-16 59.4 0.2 0.00013 22.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP14471.1 - 1.1e-15 56.2 0.9 5.4e-05 23.3 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFP14471.1 - 7.8e-14 51.4 4.4 2.1e-05 24.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP14471.1 - 2.6e-12 46.7 1.5 0.0025 18.1 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) BACK PF07707.15 KFP14471.1 - 0.00078 19.5 0.3 0.0038 17.3 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch LAGLIDADG_2 PF03161.13 KFP14471.1 - 0.16 11.9 0.7 0.35 10.9 0.3 1.7 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family GNAT_acetyltr_2 PF13718.6 KFP14472.1 - 3.7e-100 334.0 0.0 1.9e-99 331.7 0.0 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFP14472.1 - 7.1e-80 268.1 4.7 1.4e-79 267.1 4.7 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFP14472.1 - 8.8e-65 217.9 0.0 3e-64 216.1 0.0 2.0 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 KFP14472.1 - 6.1e-35 119.0 0.1 1.8e-34 117.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KFP14472.1 - 9.1e-05 22.3 0.0 0.34 10.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain Acetyltransf_7 PF13508.7 KFP14472.1 - 0.00052 20.4 0.0 0.0029 18.0 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.6 KFP14472.1 - 0.00077 19.7 0.1 2.3 8.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain Acetyltransf_1 PF00583.25 KFP14472.1 - 0.0026 18.0 0.0 0.0083 16.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP14472.1 - 0.046 13.7 0.0 8.1 6.4 0.0 3.5 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain Focal_AT PF03623.13 KFP14472.1 - 0.048 13.6 3.9 0.053 13.5 1.9 2.1 2 0 0 2 2 2 0 Focal adhesion targeting region Caprin-1_dimer PF18293.1 KFP14473.1 - 1.8e-34 118.7 0.5 1.8e-34 118.7 0.5 1.9 2 0 0 2 2 2 1 Caprin-1 dimerization domain Aida_N PF08910.10 KFP14473.1 - 0.13 12.6 2.0 0.24 11.8 2.0 1.5 1 1 0 1 1 1 0 Aida N-terminus GrpE PF01025.19 KFP14473.1 - 0.26 10.9 6.2 0.32 10.7 6.2 1.3 1 0 0 1 1 1 0 GrpE SKIP_SNW PF02731.15 KFP14473.1 - 3.2 7.4 7.6 5.1 6.7 7.6 1.3 1 0 0 1 1 1 0 SKIP/SNW domain LIM PF00412.22 KFP14474.1 - 1.5e-28 98.7 20.8 1.1e-15 57.6 9.0 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.12 KFP14474.1 - 0.019 15.2 5.4 0.019 15.2 5.4 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain TDH PF03347.13 KFP14474.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF525 PF04379.14 KFP14475.1 - 1.4e-29 102.2 0.1 4.7e-29 100.5 0.1 1.9 2 0 0 2 2 2 1 ApaG domain SMI1_KNR4 PF09346.10 KFP14475.1 - 2.9e-10 40.6 0.0 7e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KFP14475.1 - 0.0022 18.4 0.0 0.0095 16.3 0.0 2.1 1 1 1 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 KFP14475.1 - 0.035 13.8 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall UPAR_LY6 PF00021.21 KFP14476.1 - 0.048 14.4 14.3 0.22 12.3 14.3 2.0 1 1 0 1 1 1 0 u-PAR/Ly-6 domain HS1_rep PF02218.15 KFP14480.1 - 2.3e-110 360.6 68.2 1.2e-21 76.8 3.5 7.4 7 0 0 7 7 7 6 Repeat in HS1/Cortactin SH3_9 PF14604.6 KFP14480.1 - 2.4e-17 62.5 0.2 5.3e-17 61.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP14480.1 - 1.6e-16 59.6 0.2 4.3e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP14480.1 - 1.2e-09 37.7 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 KFP14480.1 - 1.5e-07 31.9 5.5 8.1 6.9 0.0 6.2 1 1 4 6 6 6 3 TMEM210 family AMP-binding_C_2 PF14535.6 KFP14480.1 - 0.23 11.8 5.3 0.45 10.8 0.6 3.2 3 1 0 3 3 3 0 AMP-binding enzyme C-terminal domain Inhibitor_I48 PF10467.9 KFP14480.1 - 0.28 11.0 2.1 1.8 8.4 0.1 2.8 2 1 1 3 3 3 0 Peptidase inhibitor clitocypin Tho2 PF11262.8 KFP14480.1 - 0.64 9.2 7.5 1.3 8.1 7.5 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PV-1 PF06637.11 KFP14480.1 - 1.3 7.8 8.3 2.2 7.0 8.3 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DED PF01335.21 KFP14483.1 - 7.9e-22 77.4 5.8 1.8e-21 76.2 4.5 2.0 2 1 0 2 2 2 1 Death effector domain Death PF00531.22 KFP14483.1 - 2.9e-18 65.8 1.1 1.4e-17 63.6 0.1 2.0 2 0 0 2 2 2 1 Death domain HTH_26 PF13443.6 KFP14483.1 - 0.055 13.9 0.2 0.63 10.5 0.0 2.7 2 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain FGF PF00167.18 KFP14485.1 - 1.1e-32 112.8 0.0 1.3e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Yae1_N PF09811.9 KFP14486.1 - 2.4e-10 39.9 4.7 3.8e-10 39.3 4.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cyclin_N PF00134.23 KFP14487.1 - 3.1e-38 130.4 2.4 3.1e-38 130.4 2.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP14487.1 - 1.6e-20 73.4 2.6 3.5e-20 72.3 0.4 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Ion_trans PF00520.31 KFP14489.1 - 4.9e-46 156.9 52.9 1.9e-23 82.9 17.0 2.2 2 0 0 2 2 2 2 Ion transport protein DUF1331 PF07048.11 KFP14489.1 - 1.1 9.0 3.3 0.72 9.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) CN_hydrolase PF00795.22 KFP14490.1 - 2.7e-42 144.9 0.0 3.6e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFP14490.1 - 6.8e-28 97.4 0.0 1.8e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KFP14490.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ERG4_ERG24 PF01222.17 KFP14491.1 - 3.2e-95 319.4 27.7 3.9e-95 319.1 27.7 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFP14491.1 - 0.011 15.3 3.0 0.011 15.3 3.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) Orf78 PF06024.12 KFP14491.1 - 0.012 15.8 0.0 0.045 14.0 0.0 2.0 1 0 0 1 1 1 0 Orf78 (ac78) ICMT PF04140.14 KFP14491.1 - 0.029 14.8 2.3 0.041 14.3 0.1 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family LIM PF00412.22 KFP14492.1 - 2.5e-29 101.3 24.8 2.1e-16 59.9 4.2 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KFP14492.1 - 0.029 14.0 13.6 0.57 9.8 0.1 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF3718 PF12514.8 KFP14492.1 - 0.05 13.8 0.9 0.079 13.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3718) Zn_ribbon_2 PF12674.7 KFP14492.1 - 0.11 13.2 13.2 0.37 11.5 1.4 2.6 2 1 0 2 2 2 0 Putative zinc ribbon domain zf-ACC PF17848.1 KFP14492.1 - 0.13 12.4 0.4 0.13 12.4 0.4 3.7 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-TFIIB PF13453.6 KFP14492.1 - 0.75 9.2 0.1 0.75 9.2 0.1 3.7 4 1 0 4 4 4 0 Transcription factor zinc-finger DUF2688 PF10892.8 KFP14492.1 - 0.75 9.3 6.0 2.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) zf-C2H2_6 PF13912.6 KFP14492.1 - 0.99 9.5 0.1 0.99 9.5 0.1 4.1 4 1 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP14492.1 - 3.8 7.7 21.1 3.1 8.0 2.6 4.0 3 1 0 3 3 3 0 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KFP14492.1 - 7.2 6.6 15.5 5.3 7.0 0.7 3.9 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS E2F_TDP PF02319.20 KFP14493.1 - 1e-42 144.0 0.3 1.4e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFP14493.1 - 7.6e-05 22.5 0.1 0.00096 19.0 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFP14493.1 - 0.0049 17.0 0.1 2.2 8.5 0.0 2.9 2 1 0 2 2 2 2 B-block binding subunit of TFIIIC Cdc6_C PF09079.11 KFP14493.1 - 0.046 13.7 0.0 6.1 6.9 0.0 2.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain PAXIP1_C PF15364.6 KFP14493.1 - 1.4 9.2 6.2 0.31 11.4 0.2 2.9 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein Homeodomain PF00046.29 KFP14495.1 - 2.5e-21 75.2 3.7 4.4e-21 74.5 3.7 1.4 1 0 0 1 1 1 1 Homeodomain DUF2986 PF11661.8 KFP14495.1 - 0.0087 16.6 1.4 0.0087 16.6 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homeobox_KN PF05920.11 KFP14495.1 - 0.0095 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP14495.1 - 0.079 12.4 0.2 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 KFP14495.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PrmA PF06325.13 KFP14496.1 - 2.5e-11 43.5 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFP14496.1 - 2.5e-10 40.9 0.3 8.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFP14496.1 - 3.4e-09 36.1 0.1 4.5e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 KFP14496.1 - 5.4e-09 36.0 0.0 1.8e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP14496.1 - 2.3e-08 34.5 0.0 8.5e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP14496.1 - 4.3e-07 29.9 0.0 4.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFP14496.1 - 6.1e-06 25.9 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KFP14496.1 - 0.00061 19.6 0.4 0.0016 18.2 0.1 1.8 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_12 PF08242.12 KFP14496.1 - 0.00066 20.4 0.0 0.0017 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFP14496.1 - 0.00075 19.0 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 KFP14496.1 - 0.0008 19.4 0.1 0.0021 18.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFP14496.1 - 0.0008 19.6 0.4 0.006 16.7 0.1 2.2 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KFP14496.1 - 0.0028 17.2 0.1 0.012 15.1 0.2 1.9 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 KFP14496.1 - 0.0058 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATP-synt_B PF00430.18 KFP14496.1 - 0.01 15.9 3.8 0.017 15.2 3.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Cons_hypoth95 PF03602.15 KFP14496.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 KFP14496.1 - 0.039 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KFP14496.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KFP14496.1 - 0.043 14.8 0.0 0.27 12.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PRMT5_C PF17286.2 KFP14496.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PRMT5 PF05185.16 KFP14496.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KFP14496.1 - 0.1 12.6 0.7 0.18 11.7 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain MCM_OB PF17207.3 KFP14496.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 MCM OB domain DUF1707 PF08044.11 KFP14496.1 - 0.17 12.0 1.3 0.35 11.0 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) EGF_CA PF07645.15 KFP14497.1 - 3e-25 88.1 54.8 7.6e-11 42.0 5.3 11.4 10 2 2 12 12 7 4 Calcium-binding EGF domain VWC PF00093.18 KFP14497.1 - 4.9e-20 71.6 78.0 1.5e-10 41.2 15.4 9.8 6 1 1 7 7 5 5 von Willebrand factor type C domain EGF_3 PF12947.7 KFP14497.1 - 3.4e-11 43.1 36.6 1.3e-08 34.9 14.6 10.9 10 1 0 10 10 8 4 EGF domain cEGF PF12662.7 KFP14497.1 - 9.9e-09 35.0 11.9 1.4e-06 28.1 2.7 11.3 11 0 0 11 11 11 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.24 KFP14497.1 - 2.3e-08 34.7 0.0 4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFP14497.1 - 1.5e-06 28.4 0.0 2.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TILa PF12714.7 KFP14497.1 - 6.2e-06 26.1 29.1 1.7e-05 24.6 10.7 11.4 6 3 4 11 11 7 4 TILa domain EGF PF00008.27 KFP14497.1 - 4.9e-05 23.5 36.3 0.0012 19.1 3.0 11.7 13 0 0 13 13 9 4 EGF-like domain Laminin_G_1 PF00054.23 KFP14497.1 - 5.6e-05 23.4 0.0 0.00015 22.0 0.0 1.6 1 1 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFP14497.1 - 0.00052 20.5 28.7 0.0044 17.6 4.0 12.9 12 1 0 12 12 10 5 Human growth factor-like EGF EGF_2 PF07974.13 KFP14497.1 - 0.0016 18.7 13.6 0.0016 18.7 13.6 12.4 10 2 1 11 11 8 2 EGF-like domain Aminotran_5 PF00266.19 KFP14503.1 - 1.8e-62 211.5 0.0 2e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V G-alpha PF00503.20 KFP14505.1 - 1.3e-110 369.9 1.7 1.4e-110 369.8 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP14505.1 - 9.1e-12 44.8 0.2 4.5e-11 42.5 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP14508.1 - 8.8e-108 360.6 4.8 1e-107 360.4 4.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP14508.1 - 1e-12 47.9 2.2 7.1e-11 41.9 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family DHHA2 PF02833.14 KFP14511.1 - 0.00019 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain FUR PF01475.19 KFP14511.1 - 0.0096 16.1 0.3 0.22 11.7 0.0 2.2 1 1 1 2 2 2 1 Ferric uptake regulator family eIF-5_eIF-2B PF01873.17 KFP14513.1 - 1.5e-42 144.2 0.6 1.2e-41 141.2 0.1 2.5 3 0 0 3 3 3 1 Domain found in IF2B/IF5 W2 PF02020.18 KFP14513.1 - 8.6e-22 77.1 1.6 8.6e-22 77.1 1.6 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Elf1 PF05129.13 KFP14513.1 - 1.1 9.3 4.0 9.4 6.4 0.7 2.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF3655 PF12379.8 KFP14513.1 - 4.3 7.7 10.6 4 7.8 2.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3655) Pkinase PF00069.25 KFP14514.1 - 1.5e-75 254.0 0.0 2.4e-75 253.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14514.1 - 2.4e-45 154.8 0.0 4.8e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFP14514.1 - 1e-21 76.5 0.2 1.7e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 KFP14514.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 KFP14514.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 KFP14514.1 - 0.00029 20.5 0.2 0.00059 19.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP14514.1 - 0.0011 18.4 0.2 0.002 17.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.11 KFP14514.1 - 0.0063 16.6 0.3 0.015 15.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Haspin_kinase PF12330.8 KFP14514.1 - 0.05 12.5 0.1 0.05 12.5 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain ATP-gua_Ptrans PF00217.19 KFP14515.1 - 1.8e-83 279.2 0.0 2.4e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFP14515.1 - 1.4e-33 115.1 0.1 2e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain GCD14 PF08704.10 KFP14516.1 - 1.5e-108 362.2 0.0 1.8e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KFP14516.1 - 2.3e-07 30.7 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP14516.1 - 3e-05 23.9 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFP14516.1 - 0.0018 18.9 0.0 0.0035 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFP14516.1 - 0.013 16.5 0.0 0.022 15.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFP14516.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F GCD14_N PF14801.6 KFP14516.1 - 0.049 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term CMAS PF02353.20 KFP14516.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2315 PF10231.9 KFP14517.1 - 6.5e-48 161.9 0.8 7.5e-48 161.7 0.8 1.0 1 0 0 1 1 1 1 Apoptogenic protein 1 Sugarporin_N PF11471.8 KFP14517.1 - 0.08 12.9 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension TPR_12 PF13424.6 KFP14518.1 - 2.8e-69 229.4 23.2 1.2e-20 73.6 2.6 5.8 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFP14518.1 - 3.9e-62 204.6 17.3 1.1e-15 57.0 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFP14518.1 - 4.1e-33 111.0 16.9 3.7e-06 26.6 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP14518.1 - 3e-29 99.6 31.3 1.2e-07 31.2 0.5 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFP14518.1 - 3.4e-21 73.6 27.2 0.00031 20.6 2.7 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFP14518.1 - 3.1e-14 51.9 26.9 0.0013 18.8 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP14518.1 - 4.2e-13 49.6 9.5 2.6e-05 24.6 0.1 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP14518.1 - 5.6e-13 49.0 2.9 5.6e-13 49.0 2.9 3.5 3 1 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 KFP14518.1 - 6.4e-13 49.1 12.9 0.00024 21.7 1.8 6.0 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP14518.1 - 3.2e-11 43.1 9.4 0.77 10.7 0.3 6.9 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP14518.1 - 1.8e-10 40.5 9.9 0.023 15.0 0.2 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFP14518.1 - 8.6e-08 32.1 0.0 8.8 7.3 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP14518.1 - 1.6e-07 31.5 11.1 0.024 14.9 1.3 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFP14518.1 - 0.00011 22.2 2.4 0.11 12.7 0.0 4.7 6 0 0 6 6 4 1 PPR repeat JIP_LZII PF16471.5 KFP14518.1 - 0.007 16.5 7.8 0.007 16.5 7.8 2.8 1 1 0 2 2 2 1 JNK-interacting protein leucine zipper II NUDE_C PF04880.13 KFP14518.1 - 0.017 15.6 3.2 0.032 14.7 3.2 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TMF_TATA_bd PF12325.8 KFP14518.1 - 0.018 15.2 11.0 0.018 15.2 11.0 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding WbqC PF08889.11 KFP14518.1 - 0.023 14.6 7.7 8.8 6.2 0.0 4.1 3 1 1 4 4 4 0 WbqC-like protein family SHNi-TPR PF10516.9 KFP14518.1 - 0.083 12.4 4.9 8.4 5.9 0.1 4.7 5 0 0 5 5 5 0 SHNi-TPR PPR_2 PF13041.6 KFP14518.1 - 0.09 13.0 3.0 2.9 8.2 0.0 3.8 4 0 0 4 4 3 0 PPR repeat family GHL5 PF14872.6 KFP14518.1 - 0.099 10.7 5.9 0.15 10.1 5.9 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 DUF627 PF04781.12 KFP14518.1 - 0.14 12.2 5.5 2.1 8.4 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF627) DUF4919 PF16266.5 KFP14518.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.5 2 2 1 4 4 4 0 Domain of unknown function (DUF4919) TPR_11 PF13414.6 KFP14518.1 - 0.46 10.2 20.2 0.25 11.1 0.7 6.4 6 0 0 6 6 6 0 TPR repeat COG2 PF06148.11 KFP14518.1 - 0.52 10.4 9.5 0.21 11.7 5.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Gly_radical PF01228.21 KFP14518.1 - 1.9 9.1 5.6 50 4.5 0.0 4.3 2 2 3 5 5 5 0 Glycine radical MIT PF04212.18 KFP14518.1 - 3 8.0 17.2 27 4.9 3.2 5.9 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain YabA PF06156.13 KFP14518.1 - 5.8 7.6 19.2 0.084 13.5 5.1 3.7 3 0 0 3 3 3 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 KFP14518.1 - 6.1 7.5 22.2 20 5.9 9.2 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_3 PF07720.12 KFP14518.1 - 6.7 6.8 16.3 3.5 7.7 1.5 5.3 6 1 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.32 KFP14522.1 - 4.4e-11 43.1 9.7 1e-05 26.1 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14522.1 - 0.0019 18.5 0.3 8.1 6.8 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP14522.1 - 0.0021 16.8 0.0 0.0081 14.8 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Lipoprotein_3 PF00938.17 KFP14522.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein DUF775 PF05603.12 KFP14523.1 - 1.2e-42 145.8 0.3 1.7e-42 145.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RVT_1 PF00078.27 KFP14525.1 - 0.01 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ten_N PF06484.12 KFP14537.1 - 1e-31 111.2 6.9 1.1e-31 111.0 6.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region DUF1203 PF06718.11 KFP14537.1 - 0.056 13.7 0.1 0.069 13.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1203) Ten_N PF06484.12 KFP14538.1 - 2.7e-31 109.8 12.4 3.8e-31 109.3 12.4 1.2 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.6 KFP14538.1 - 1.7e-30 104.8 0.7 3.2e-30 103.9 0.7 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 KFP14538.1 - 2.5e-20 72.5 157.7 0.00024 21.4 13.4 9.6 9 0 0 9 9 9 8 EGF-like domain RHS_repeat PF05593.14 KFP14538.1 - 2.7e-15 56.5 27.6 0.00046 20.6 0.0 9.4 8 1 2 10 10 10 5 RHS Repeat NHL PF01436.21 KFP14538.1 - 4.1e-07 29.7 5.4 0.015 15.3 0.0 5.9 6 0 0 6 6 6 2 NHL repeat CarboxypepD_reg PF13620.6 KFP14538.1 - 0.029 14.6 1.6 0.067 13.5 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain NAGLU_N PF12971.7 KFP14538.1 - 0.034 13.9 0.1 1.6 8.6 0.0 3.1 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain hEGF PF12661.7 KFP14538.1 - 2 9.2 118.4 0.027 15.1 7.3 9.6 9 0 0 9 9 9 0 Human growth factor-like EGF I-EGF_1 PF18372.1 KFP14538.1 - 3.5 7.8 113.6 0.1 12.7 5.8 8.9 8 1 0 8 8 8 0 Integrin beta epidermal growth factor like domain 1 tRNA-synt_2 PF00152.20 KFP14539.1 - 1.5e-98 329.8 0.0 1.8e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP14539.1 - 1.7e-08 34.3 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFP14539.1 - 0.00071 19.1 0.9 0.8 9.1 0.5 2.6 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KFP14539.1 - 0.079 12.9 0.2 0.56 10.1 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF4312 PF14189.6 KFP14539.1 - 0.17 11.9 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) PH PF00169.29 KFP14540.1 - 8.5e-19 68.0 0.4 3.9e-18 65.9 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP14540.1 - 8.4e-05 23.0 4.0 0.00019 21.8 1.5 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFP14540.1 - 0.029 14.2 0.3 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 KFP14540.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_3 PF14593.6 KFP14540.1 - 0.21 11.7 0.4 0.69 10.1 0.4 1.8 1 1 0 1 1 1 0 PH domain UCH PF00443.29 KFP14541.1 - 1.7e-43 149.0 0.0 3.8e-43 147.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP14541.1 - 1.3e-24 87.3 0.0 4.4e-24 85.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDR PF08841.10 KFP14541.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain BTB_2 PF02214.22 KFP14542.1 - 2.5e-21 75.8 0.0 5.5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP14542.1 - 6.9e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Alg6_Alg8 PF03155.15 KFP14543.1 - 9.2e-169 562.5 30.1 1.1e-168 562.3 30.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family NDUF_C2 PF06374.11 KFP14544.1 - 7e-25 87.3 0.1 7.6e-25 87.2 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Spot_14 PF07084.12 KFP14545.1 - 1.5e-24 86.8 0.1 1.9e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 ATG16 PF08614.11 KFP14545.1 - 0.048 13.9 0.4 0.062 13.5 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spot_14 PF07084.12 KFP14546.1 - 1.4e-21 77.3 0.1 3e-21 76.2 0.1 1.5 1 1 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 BTB_2 PF02214.22 KFP14547.1 - 7.2e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Phage_Mu_Gam PF07352.12 KFP14547.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein HEAT PF02985.22 KFP14548.1 - 2.7e-19 67.6 6.9 0.021 15.0 0.0 8.5 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KFP14548.1 - 6.8e-15 55.2 6.3 1.2e-05 25.6 0.1 5.2 4 1 2 6 6 6 2 HEAT repeats Adaptin_N PF01602.20 KFP14548.1 - 6.8e-10 38.1 5.1 0.00071 18.3 0.1 3.3 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 KFP14548.1 - 3.1e-09 37.1 5.5 0.0022 18.0 0.5 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFP14548.1 - 4.6e-08 33.5 0.8 0.0005 20.6 0.1 4.5 4 2 1 5 5 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFP14548.1 - 9e-06 25.4 0.6 4.1 6.9 0.1 4.7 2 2 3 5 5 5 2 CLASP N terminal Cnd3 PF12719.7 KFP14548.1 - 0.00031 20.0 4.1 0.096 11.9 0.1 2.8 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KFP14548.1 - 0.0019 18.4 3.1 0.87 9.8 0.1 4.4 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF445 PF04286.12 KFP14548.1 - 0.013 15.3 3.1 0.3 10.8 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Cohesin_HEAT PF12765.7 KFP14548.1 - 0.014 15.7 2.8 0.19 12.0 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.16 KFP14548.1 - 0.12 13.1 0.6 41 5.2 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3338 PF11819.8 KFP14548.1 - 0.12 12.4 0.2 2 8.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Baculo_PEP_C PF04513.12 KFP14548.1 - 0.24 11.4 2.6 7.3 6.6 0.5 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MMS19_N PF14500.6 KFP14548.1 - 0.36 10.4 4.5 5.1 6.6 0.0 3.9 3 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF498 PF04430.14 KFP14550.1 - 1.7e-20 73.1 0.0 1.8e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Indigoidine_A PF04227.12 KFP14550.1 - 0.027 13.8 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Indigoidine synthase A like protein HflK_N PF12221.8 KFP14550.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane protein N terminal EspA PF03433.13 KFP14550.1 - 0.098 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 EspA-like secreted protein WHIM1 PF15612.6 KFP14551.1 - 1.1e-11 44.0 0.1 2.5e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PHD PF00628.29 KFP14551.1 - 1.9e-10 40.5 4.3 7.5e-10 38.5 4.3 2.2 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFP14551.1 - 0.27 11.2 2.5 0.96 9.4 2.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Cupredoxin_1 PF13473.6 KFP14551.1 - 0.38 10.9 2.4 2.4 8.3 2.4 2.4 1 0 0 1 1 1 0 Cupredoxin-like domain PHD_2 PF13831.6 KFP14551.1 - 1.8 8.2 4.5 1.4 8.6 0.2 2.9 3 0 0 3 3 3 0 PHD-finger Voldacs PF03517.13 KFP14553.1 - 1.9e-28 99.3 2.1 2.8e-28 98.8 2.1 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling MIP PF00230.20 KFP14554.1 - 8.1e-09 35.5 7.5 8.4e-09 35.5 4.9 1.8 1 1 1 2 2 2 2 Major intrinsic protein SLATT_5 PF18160.1 KFP14554.1 - 0.032 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 GDPD PF03009.17 KFP14556.1 - 9.8e-17 61.5 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Myosin_head PF00063.21 KFP14557.1 - 2.8e-245 815.7 4.9 3.8e-245 815.3 4.9 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 KFP14557.1 - 4.4e-64 213.7 0.1 4e-32 110.9 0.0 3.3 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 KFP14557.1 - 9.7e-27 93.7 10.3 2e-18 66.9 0.0 4.5 5 0 0 5 5 4 2 FERM central domain IQ PF00612.27 KFP14557.1 - 1.4e-15 55.5 23.2 0.0001 21.7 0.2 6.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif FERM_N PF09379.10 KFP14557.1 - 6.8e-09 35.5 0.2 0.0036 17.2 0.1 2.7 2 0 0 2 2 2 2 FERM N-terminal domain SH3_9 PF14604.6 KFP14557.1 - 0.018 14.9 0.1 0.087 12.7 0.1 2.3 1 0 0 1 1 1 0 Variant SH3 domain PID PF00640.23 KFP14557.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) AAA_22 PF13401.6 KFP14557.1 - 0.04 14.2 3.3 0.18 12.1 0.0 3.6 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.6 KFP14557.1 - 0.046 14.1 0.6 0.36 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain SH3_1 PF00018.28 KFP14557.1 - 0.051 13.2 1.8 0.46 10.1 0.1 2.9 3 0 0 3 3 3 0 SH3 domain SH3_2 PF07653.17 KFP14557.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain DUF3752 PF12572.8 KFP14557.1 - 0.22 12.0 7.9 0.55 10.7 7.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ABC_tran PF00005.27 KFP14557.1 - 0.26 11.8 2.0 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF4407 PF14362.6 KFP14557.1 - 2.5 7.4 7.1 4.4 6.6 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C2 PF00648.21 KFP14558.1 - 3.4e-123 410.4 1.2 4.6e-123 410.0 1.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP14558.1 - 7.8e-38 129.9 0.0 1.3e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 KFP14558.1 - 1.2e-11 44.7 0.0 3.5e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ceramidase PF05875.12 KFP14560.1 - 1e-59 202.1 12.4 1.3e-59 201.8 12.4 1.0 1 0 0 1 1 1 1 Ceramidase DUF5317 PF17248.2 KFP14560.1 - 7.2 6.6 10.9 0.56 10.2 3.1 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5317) LRR_8 PF13855.6 KFP14561.1 - 2.2e-37 126.6 26.5 2.5e-12 46.3 2.2 6.5 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP14561.1 - 4.3e-21 74.7 35.8 5.5e-05 23.5 2.5 7.4 4 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP14561.1 - 7.1e-12 45.4 0.1 1.6e-05 24.8 0.3 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP14561.1 - 4.1e-11 41.8 23.9 0.079 13.5 0.3 9.6 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP14561.1 - 1.3e-05 24.9 27.7 0.75 10.0 0.0 8.8 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.6 KFP14561.1 - 0.0027 17.2 6.2 1 8.9 1.8 3.2 1 1 2 3 3 3 2 Leucine-rich repeat LRRNT PF01462.18 KFP14561.1 - 0.11 12.2 2.6 0.5 10.1 0.6 2.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Guanylate_cyc PF00211.20 KFP14564.1 - 8.5e-66 221.1 0.0 2.3e-65 219.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 KFP14564.1 - 7.2e-65 219.4 0.0 1e-64 218.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.17 KFP14564.1 - 8.8e-37 126.8 0.0 1.4e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP14564.1 - 1.4e-26 93.5 0.0 2.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KFP14564.1 - 1.7e-05 24.4 1.7 3.1e-05 23.5 1.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Catalase_C PF18011.1 KFP14564.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain found in long catalases Kinase-like PF14531.6 KFP14564.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like ENT PF03735.14 KFP14566.1 - 1.2e-24 86.1 0.1 2.2e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 ENT domain MRP_L53 PF10780.9 KFP14566.1 - 0.19 11.9 2.4 0.8 9.9 0.2 3.3 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 DUF4371 PF14291.6 KFP14567.1 - 4.1e-12 46.2 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.14 KFP14567.1 - 3.7e-10 39.4 0.0 9.8e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region THAP PF05485.12 KFP14567.1 - 1.3e-08 35.7 0.4 4.1e-08 34.0 0.4 2.0 1 0 0 1 1 1 1 THAP domain DUF659 PF04937.15 KFP14567.1 - 0.61 9.9 3.0 12 5.8 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF 659) Yae1_N PF09811.9 KFP14570.1 - 4e-17 61.6 61.7 1.8e+04 -26.6 61.7 5.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal wnt PF00110.19 KFP14571.1 - 1.2e-107 360.1 16.0 1.4e-107 359.9 16.0 1.0 1 0 0 1 1 1 1 wnt family DUF4462 PF14692.6 KFP14572.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Atg14 PF10186.9 KFP14573.1 - 2.3e-18 66.4 8.9 5.1e-18 65.2 8.9 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KFP14573.1 - 7e-11 41.7 6.3 1.4e-10 40.7 6.3 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 38 C2 PF00168.30 KFP14573.1 - 0.00031 21.0 0.0 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 C2 domain TPR_MLP1_2 PF07926.12 KFP14573.1 - 0.015 15.4 9.0 0.031 14.4 9.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3367 PF11847.8 KFP14573.1 - 0.28 9.0 0.2 0.39 8.5 0.2 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase DUF3585 PF12130.8 KFP14573.1 - 0.99 9.5 10.7 2.2 8.4 10.7 1.6 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Cnn_1N PF07989.11 KFP14573.1 - 1.1 9.4 9.2 5.9 7.1 8.9 2.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DAGAT PF03982.13 KFP14576.1 - 9.1e-142 471.3 0.0 1.1e-141 471.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 KFP14576.1 - 0.005 16.5 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Nckap1 PF09735.9 KFP14578.1 - 4.3e-32 111.1 0.2 4.7e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein RVT_1 PF00078.27 KFP14579.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP14580.1 - 4.6e-33 114.6 0.0 7.3e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP14580.1 - 3.2e-17 62.1 2.1 6.6e-17 61.1 2.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Strabismus PF06638.11 KFP14581.1 - 1.9e-209 696.5 0.0 6.4e-126 421.0 0.0 2.0 2 0 0 2 2 2 2 Strabismus protein Keratin PF02422.16 KFP14582.1 - 3.3e-25 87.6 4.7 3.6e-25 87.5 4.7 1.0 1 0 0 1 1 1 1 Keratin NEMP PF10225.9 KFP14583.1 - 0.029 14.1 0.6 0.044 13.5 0.6 1.3 1 0 0 1 1 1 0 NEMP family NEMP PF10225.9 KFP14584.1 - 1.9e-22 80.1 0.0 2.1e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 NEMP family DUF945 PF06097.11 KFP14585.1 - 8.3e-10 38.4 0.0 3.1 6.8 0.0 8.3 2 2 3 6 6 6 2 Bacterial protein of unknown function (DUF945) DUF2993 PF11209.8 KFP14585.1 - 2.1e-09 37.9 0.0 6.9 6.9 0.0 9.6 2 1 7 9 9 9 1 Protein of unknown function (DUF2993) DUF211 PF02680.14 KFP14585.1 - 0.00024 21.2 2.6 50 4.2 0.0 8.7 12 0 0 12 12 12 0 Uncharacterized ArCR, COG1888 DUF2125 PF09898.9 KFP14585.1 - 0.0021 17.8 0.0 49 3.4 0.0 5.4 3 2 5 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2125) DNA_pol3_alpha PF07733.12 KFP14585.1 - 0.0074 15.9 6.8 84 2.6 0.0 6.8 8 0 0 8 8 8 0 Bacterial DNA polymerase III alpha NTPase domain ELFV_dehydrog_N PF02812.18 KFP14585.1 - 0.13 12.2 7.6 79 3.1 0.1 6.3 6 0 0 6 6 6 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ZU5 PF00791.20 KFP14585.1 - 0.21 12.0 5.6 1e+02 3.3 0.0 6.6 7 1 0 7 7 7 0 ZU5 domain Gas_vesicle PF00741.18 KFP14585.1 - 5.4 7.2 5.7 51 4.1 0.1 5.3 7 0 0 7 7 7 0 Gas vesicle protein Ntox37 PF15535.6 KFP14585.1 - 9 6.8 39.4 1.2 9.6 0.5 11.3 5 4 6 11 11 11 0 Bacterial toxin 37 DUF945 PF06097.11 KFP14586.1 - 1.4e-11 44.2 0.0 3.4 6.7 0.0 8.0 5 3 2 8 8 8 5 Bacterial protein of unknown function (DUF945) DUF2993 PF11209.8 KFP14586.1 - 3e-06 27.6 0.4 40 4.4 0.0 9.4 3 2 5 10 10 10 0 Protein of unknown function (DUF2993) Ntox37 PF15535.6 KFP14586.1 - 4.7e-05 23.7 44.8 0.67 10.4 0.6 13.6 7 5 5 13 13 13 4 Bacterial toxin 37 DNA_pol3_alpha PF07733.12 KFP14586.1 - 0.00092 18.9 13.2 81 2.7 0.0 9.1 11 0 0 11 11 11 0 Bacterial DNA polymerase III alpha NTPase domain DUF2125 PF09898.9 KFP14586.1 - 0.0014 18.4 0.0 73 2.9 0.0 6.2 8 1 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2125) adh_short PF00106.25 KFP14587.1 - 1.1e-40 139.2 0.0 1.5e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP14587.1 - 7.8e-23 81.2 0.0 1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP14587.1 - 7e-06 26.1 0.0 9.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP14587.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RecA PF00154.21 KFP14587.1 - 0.053 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein GSG-1 PF07803.11 KFP14589.1 - 2.8e-46 156.2 0.4 5.3e-46 155.3 0.4 1.5 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFP14589.1 - 2e-08 34.3 9.0 5.3e-08 32.9 9.1 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP14589.1 - 1.5e-06 28.1 12.7 1.8e-05 24.6 12.7 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 KFP14589.1 - 0.014 15.6 7.6 0.049 13.8 7.6 1.8 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein CD20 PF04103.15 KFP14589.1 - 0.95 9.5 12.4 8.2 6.5 6.8 3.6 3 1 0 3 3 3 0 CD20-like family 7tm_2 PF00002.24 KFP14590.1 - 2.8e-77 259.3 15.0 3.6e-77 259.0 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP14590.1 - 3.3e-14 52.9 3.8 7.8e-14 51.7 3.8 1.7 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.12 KFP14590.1 - 0.018 14.7 0.7 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 SUR7/PalI family DUF1156 PF06634.12 KFP14590.1 - 0.082 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) WW_FCH_linker PF16623.5 KFP14591.1 - 2.3e-33 114.8 0.3 1.1e-32 112.7 0.3 2.2 1 0 0 1 1 1 1 Unstructured linker region between on GAS7 protein FCH PF00611.23 KFP14591.1 - 1.3e-14 54.2 4.2 1.3e-14 54.2 4.2 2.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain WW PF00397.26 KFP14591.1 - 7.3e-13 48.4 3.4 1.4e-12 47.4 3.4 1.5 1 0 0 1 1 1 1 WW domain DUF1664 PF07889.12 KFP14591.1 - 0.021 14.9 4.3 0.021 14.9 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 KFP14591.1 - 1 9.1 5.6 0.36 10.6 2.2 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF2935 PF11155.8 KFP14591.1 - 8.2 6.8 8.8 81 3.6 4.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) 7tm_4 PF13853.6 KFP14598.1 - 6.1e-48 163.9 12.8 7.2e-48 163.7 12.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP14598.1 - 1.3e-28 100.1 13.8 1.7e-28 99.7 13.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP14599.1 - 3.2e-08 33.6 0.9 3.7e-08 33.4 0.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP14599.1 - 2.5e-05 23.7 0.1 4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP14599.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal GCM PF03615.15 KFP14600.1 - 4.2e-72 240.6 1.5 6.6e-72 239.9 1.5 1.3 1 0 0 1 1 1 1 GCM motif protein FixO PF02433.15 KFP14600.1 - 0.047 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO ELO PF01151.18 KFP14601.1 - 6.5e-60 202.8 23.1 7.4e-60 202.6 23.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DKCLD PF08068.12 KFP14602.1 - 4.7e-24 84.2 0.2 2.2e-23 82.1 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KFP14602.1 - 4.1e-22 78.1 0.3 7.8e-22 77.2 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KFP14602.1 - 7.6e-20 71.8 7.0 2.5e-18 66.9 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KFP14602.1 - 4.6e-18 65.0 1.0 1.2e-17 63.6 1.0 1.8 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KFP14602.1 - 0.0028 17.9 0.0 0.0072 16.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 KFP14602.1 - 4.7 7.4 12.9 7.4 6.8 12.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Guanylate_kin PF00625.21 KFP14603.1 - 1.2e-61 207.6 0.1 2.2e-61 206.7 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFP14603.1 - 2.1e-19 69.7 2.6 2.3e-19 69.5 1.1 1.9 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 KFP14603.1 - 1.2e-10 40.9 0.0 3.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP14603.1 - 1.2e-08 34.5 1.0 5.5e-08 32.3 1.0 2.1 1 1 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 KFP14603.1 - 5.4e-06 26.2 0.3 1.7e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 PDZ domain SH3_9 PF14604.6 KFP14603.1 - 2.3e-05 24.2 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KFP14603.1 - 0.00012 22.3 0.2 0.00095 19.5 0.1 2.2 2 0 0 2 2 2 1 PDZ domain RsgA_GTPase PF03193.16 KFP14603.1 - 0.00072 19.5 0.0 0.0072 16.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Tricorn_PDZ PF14685.6 KFP14603.1 - 0.0017 18.3 0.5 0.24 11.4 0.1 3.2 3 1 0 3 3 3 1 Tricorn protease PDZ domain AAA_7 PF12775.7 KFP14603.1 - 0.035 13.6 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KFP14603.1 - 0.036 14.1 0.0 0.093 12.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PDZ_4 PF17816.1 KFP14603.1 - 0.052 14.0 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 PDZ domain FUN14 PF04930.15 KFP14604.1 - 1.4e-26 92.8 2.8 1.7e-26 92.4 2.8 1.1 1 0 0 1 1 1 1 FUN14 family SPC12 PF06645.13 KFP14604.1 - 0.24 11.5 2.2 0.25 11.5 0.3 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MTCP1 PF08991.10 KFP14605.1 - 6.3e-09 35.9 5.5 7.5e-09 35.7 5.5 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Copine PF07002.16 KFP14605.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Copine TCL1_MTCP1 PF01840.17 KFP14606.1 - 1.2e-16 60.4 0.1 1.2e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 TCL1/MTCP1 family Sod_Fe_C PF02777.18 KFP14607.1 - 2.8e-38 130.2 0.0 4.9e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFP14607.1 - 1.7e-33 114.9 3.3 2.6e-33 114.3 3.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Wtap PF17098.5 KFP14608.1 - 1.7e-61 206.7 14.1 1.7e-61 206.7 14.1 2.3 2 0 0 2 2 2 1 WTAP/Mum2p family ADIP PF11559.8 KFP14608.1 - 0.19 11.8 26.4 0.52 10.4 5.8 3.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KFP14608.1 - 0.24 10.5 18.7 1.3 8.1 3.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 KFP14608.1 - 0.37 11.7 22.7 2.3 9.2 5.4 3.5 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Lipoprotein_7 PF01540.16 KFP14608.1 - 0.61 9.3 5.7 0.16 11.2 2.1 1.7 1 1 1 2 2 2 0 Adhesin lipoprotein AAA_13 PF13166.6 KFP14608.1 - 1.4 7.4 13.6 2.1 6.9 13.6 1.3 1 0 0 1 1 1 0 AAA domain DUF1043 PF06295.12 KFP14608.1 - 3.9 7.5 24.0 0.04 13.9 7.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1043) OmpH PF03938.14 KFP14608.1 - 4.1 7.7 38.6 0.31 11.4 5.2 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF2120 PF09893.9 KFP14608.1 - 5.4 7.1 6.2 1.7 8.8 0.2 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Thiolase_N PF00108.23 KFP14609.1 - 8.2e-79 264.6 2.2 1.1e-78 264.2 2.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP14609.1 - 3.6e-50 168.7 0.6 6.9e-50 167.8 0.6 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP14609.1 - 0.00025 20.7 3.6 0.00031 20.4 1.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 KFP14609.1 - 0.0029 17.8 0.1 0.0074 16.5 0.1 1.7 1 0 0 1 1 1 1 Dodecin ACP_syn_III_C PF08541.10 KFP14609.1 - 0.0053 16.9 0.1 0.016 15.3 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cpn60_TCP1 PF00118.24 KFP14610.1 - 1.7e-153 511.8 14.4 2e-153 511.6 14.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CAF1 PF04857.20 KFP14611.1 - 2.3e-57 194.6 0.0 4.9e-56 190.2 0.0 2.0 1 1 0 1 1 1 1 CAF1 family ribonuclease 7tm_1 PF00001.21 KFP14612.1 - 1.8e-17 63.5 28.4 1.8e-17 63.5 28.4 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP14612.1 - 1e-08 35.2 23.4 1e-08 35.2 23.4 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFP14612.1 - 0.0044 17.0 14.0 0.0044 17.0 14.0 2.8 1 1 3 4 4 4 1 Caenorhabditis serpentine receptor-like protein, class xa ISK_Channel PF02060.15 KFP14612.1 - 0.14 11.9 2.0 0.86 9.3 0.0 2.6 2 1 1 3 3 3 0 Slow voltage-gated potassium channel PEN-2 PF10251.9 KFP14612.1 - 9.6 6.7 10.1 2.2 8.7 0.2 3.5 2 1 2 4 4 4 0 Presenilin enhancer-2 subunit of gamma secretase CIMR PF00878.18 KFP14613.1 - 0 1240.1 93.9 1.8e-51 174.0 1.8 16.3 16 0 0 16 16 16 16 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KFP14613.1 - 2.6e-62 211.1 95.0 1.2e-08 35.1 0.6 16.1 3 2 12 15 15 15 13 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KFP14613.1 - 7.9e-48 162.8 39.0 3.7e-10 39.3 1.0 14.0 4 3 10 14 14 14 11 Mannose-6-phosphate receptor fn2 PF00040.19 KFP14613.1 - 2.3e-18 66.2 8.1 1e-17 64.1 8.1 2.3 1 0 0 1 1 1 1 Fibronectin type II domain PRKCSH_1 PF13015.6 KFP14613.1 - 2.1e-07 30.8 41.1 0.015 15.0 0.1 10.7 11 1 1 12 12 12 4 Glucosidase II beta subunit-like protein DUF4448 PF14610.6 KFP14613.1 - 0.00035 20.4 0.6 8.2 6.2 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF4448) Sugar_tr PF00083.24 KFP14614.1 - 6.1e-36 124.2 7.9 6.1e-36 124.2 7.9 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP14614.1 - 1.3e-26 93.4 27.1 1e-24 87.1 13.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFP14614.1 - 0.0025 17.2 0.5 0.0025 17.2 0.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2897 PF11446.8 KFP14614.1 - 6 6.8 5.4 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Kringle PF00051.18 KFP14615.1 - 2e-144 470.3 73.4 1.2e-30 105.6 9.3 5.4 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.26 KFP14615.1 - 2.6e-62 210.5 0.1 4.3e-62 209.8 0.1 1.4 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFP14615.1 - 2.8e-11 43.2 1.6 2.8e-11 43.2 1.6 2.6 2 0 0 2 2 2 1 PAN domain Trypsin_2 PF13365.6 KFP14615.1 - 3e-09 37.9 0.0 6.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP14615.1 - 7.8e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF1137 PF06587.11 KFP14615.1 - 0.24 11.4 0.5 0.47 10.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) KduI PF04962.12 KFP14615.1 - 2.3 7.5 10.6 3.4 6.9 0.1 3.2 3 0 0 3 3 3 0 KduI/IolB family Kringle PF00051.18 KFP14616.1 - 1.2e-144 470.9 64.8 8.2e-31 106.2 6.2 5.5 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.26 KFP14616.1 - 4.9e-45 154.0 0.1 8.4e-45 153.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP14616.1 - 2.6e-11 43.9 0.1 4.7e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PAN_1 PF00024.26 KFP14616.1 - 1.5e-07 31.2 4.8 2.9e-07 30.3 3.3 2.4 2 0 0 2 2 2 1 PAN domain DUF3719 PF12516.8 KFP14616.1 - 9.4 6.0 8.6 36 4.1 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3719) Pkinase PF00069.25 KFP14617.1 - 2.7e-70 236.7 0.0 6e-70 235.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14617.1 - 1.2e-41 142.8 0.0 2.7e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14617.1 - 4.2e-08 32.8 0.0 8.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP14617.1 - 0.0016 17.3 0.0 0.0016 17.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KFP14617.1 - 0.007 16.0 0.1 0.063 12.9 0.0 2.5 2 1 1 3 3 3 1 RIO1 family PLU-1 PF08429.11 KFP14617.1 - 4.5 6.3 9.6 0.21 10.7 0.1 3.2 4 0 0 4 4 4 0 PLU-1-like protein Acyltransf_C PF16076.5 KFP14618.1 - 2.8e-27 94.6 0.2 5.2e-27 93.8 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFP14618.1 - 2.8e-15 56.1 0.0 4.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ubiquitin PF00240.23 KFP14619.1 - 5.1e-08 32.5 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFP14619.1 - 0.0014 19.2 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Sporozoite_P67 PF05642.11 KFP14619.1 - 0.026 12.6 3.1 0.77 7.8 5.4 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Septin PF00735.18 KFP14620.1 - 6.9e-124 412.7 0.2 7.9e-124 412.5 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP14620.1 - 2e-07 31.1 0.0 4.2e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP14620.1 - 4.8e-07 29.8 3.6 0.00014 21.8 0.4 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFP14620.1 - 0.00014 21.3 1.2 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AIG1 PF04548.16 KFP14620.1 - 0.00018 20.9 0.1 0.00053 19.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 KFP14620.1 - 0.00053 19.6 0.6 0.33 10.5 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFP14620.1 - 0.0051 17.3 0.0 0.014 15.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KFP14620.1 - 0.0059 16.9 0.0 0.02 15.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFP14620.1 - 0.0061 16.6 4.2 0.43 10.6 0.3 3.0 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 KFP14620.1 - 0.007 16.8 0.0 0.016 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 KFP14620.1 - 0.0074 15.9 0.1 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 KFP14620.1 - 0.0075 15.5 0.6 4.2 6.4 0.1 2.7 2 1 1 3 3 3 2 G-protein alpha subunit FeoB_N PF02421.18 KFP14620.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KFP14620.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFP14620.1 - 0.035 13.6 0.1 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region HEPPP_synt_1 PF07307.11 KFP14620.1 - 0.049 13.2 0.3 0.079 12.5 0.3 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Roc PF08477.13 KFP14620.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFP14620.1 - 0.092 12.8 0.1 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KFP14620.1 - 0.15 11.2 1.0 0.34 10.1 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain DUF1542 PF07564.11 KFP14620.1 - 0.32 11.1 3.0 1 9.5 3.0 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) HHH_3 PF12836.7 KFP14621.1 - 5.8e-42 141.8 0.2 1.2e-20 73.5 0.1 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 KFP14621.1 - 4.1e-17 61.1 0.1 1.3e-06 27.9 0.0 3.7 3 0 0 3 3 3 3 Helix-hairpin-helix motif HHH_6 PF14579.6 KFP14621.1 - 7.8e-09 35.7 0.0 6e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif T2SSK PF03934.13 KFP14621.1 - 3.9e-08 33.0 0.0 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K Exo_endo_phos PF03372.23 KFP14621.1 - 4.4e-08 32.9 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_2 PF12826.7 KFP14621.1 - 1.4e-07 31.5 0.1 0.022 14.9 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KFP14621.1 - 1.3e-05 25.7 0.2 1.1 9.9 0.1 4.0 3 2 2 5 5 5 4 Helix-hairpin-helix domain PsbU PF06514.11 KFP14621.1 - 0.0061 16.5 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) Exo_endo_phos_2 PF14529.6 KFP14621.1 - 0.03 14.2 0.5 0.09 12.6 0.5 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1704 PF08014.11 KFP14622.1 - 8.4e-16 57.9 0.0 1.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) Anillin PF08174.11 KFP14623.1 - 2.6e-38 131.6 0.1 6.8e-38 130.3 0.1 1.8 1 0 0 1 1 1 1 Cell division protein anillin Anillin_N PF16018.5 KFP14623.1 - 4.2e-38 129.8 10.8 6.6e-34 116.4 0.7 3.9 3 0 0 3 3 3 2 Anillin N-terminus PH PF00169.29 KFP14623.1 - 5.2e-18 65.5 1.3 1.6e-17 63.9 0.2 2.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KFP14623.1 - 0.019 15.4 0.1 0.076 13.4 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Lipase_GDSL PF00657.22 KFP14624.1 - 2.7e-13 50.3 0.0 4.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cu-binding_MopE PF11617.8 KFP14624.1 - 0.0037 17.4 1.9 0.0037 17.4 1.9 2.3 2 1 0 2 2 2 1 Putative metal-binding motif DUF3361 PF11841.8 KFP14625.1 - 6.6e-62 208.0 3.5 1.4e-61 207.0 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFP14625.1 - 1.3e-42 145.9 0.9 2.6e-42 144.9 0.9 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFP14625.1 - 7.8e-39 133.3 0.2 3.2e-38 131.3 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain ZFYVE21_C PF16696.5 KFP14625.1 - 0.067 13.1 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus FERM_N PF09379.10 KFP14625.1 - 0.079 12.9 0.0 0.71 9.9 0.0 2.5 3 0 0 3 3 3 0 FERM N-terminal domain 7tm_1 PF00001.21 KFP14626.1 - 7.3e-09 35.3 26.8 1.6e-08 34.2 26.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Thioredoxin PF00085.20 KFP14627.1 - 1.3e-06 28.3 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KFP14627.1 - 0.0019 18.1 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP14627.1 - 0.002 17.8 0.1 0.0025 17.5 0.1 1.4 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 KFP14627.1 - 0.0099 16.1 0.0 0.017 15.3 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin Ependymin PF00811.18 KFP14628.1 - 3.6e-37 127.5 0.3 4e-37 127.3 0.3 1.0 1 0 0 1 1 1 1 Ependymin Rpn9_C PF18261.1 KFP14628.1 - 0.23 11.1 0.8 8.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Rpn9 C-terminal helix Pkinase PF00069.25 KFP14629.1 - 4e-57 193.6 0.4 6.2e-57 193.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14629.1 - 1.4e-32 113.0 0.0 2.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14629.1 - 1.8e-09 37.3 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP14629.1 - 0.00039 19.3 0.0 0.00081 18.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP14629.1 - 0.0071 15.7 0.3 0.0071 15.7 0.3 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP14629.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP14629.1 - 0.038 12.9 0.2 0.057 12.4 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Cadherin PF00028.17 KFP14633.1 - 2.6e-92 303.5 0.0 1.2e-17 64.1 0.0 6.4 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KFP14633.1 - 2.2e-12 46.6 0.1 1.2e-09 37.8 0.1 4.1 4 0 0 4 4 4 1 Cadherin-like Cadherin_4 PF17803.1 KFP14633.1 - 1.4e-05 25.6 6.4 0.16 12.6 0.0 4.9 4 0 0 4 4 4 2 Bacterial cadherin-like domain Cadherin_C_2 PF16492.5 KFP14633.1 - 2.1e-05 25.2 0.0 7.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal TGF_beta PF00019.20 KFP14640.1 - 7.3e-31 107.2 1.2 1.6e-30 106.2 1.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP14640.1 - 7.5e-09 35.7 1.6 5.8e-08 32.8 1.6 2.2 1 1 0 1 1 1 1 TGF-beta propeptide CoA_transf_3 PF02515.17 KFP14644.1 - 1.5e-63 215.1 0.0 1.7e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Pkinase PF00069.25 KFP14645.1 - 1.8e-74 250.5 0.0 2.8e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14645.1 - 1.9e-35 122.4 0.0 3.1e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP14645.1 - 6.8e-08 31.8 0.3 6.8e-08 31.8 0.3 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFP14645.1 - 1.1e-05 24.9 0.0 9.1e-05 21.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP14645.1 - 0.014 14.7 0.2 0.027 13.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP14645.1 - 0.23 10.2 0.0 0.23 10.2 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase THRAP3_BCLAF1 PF15440.6 KFP14645.1 - 0.76 8.7 21.5 2.3 7.1 21.5 1.9 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Yae1_N PF09811.9 KFP14646.1 - 7.7e-18 63.9 63.5 1.8e+04 -28.3 63.5 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ig_3 PF13927.6 KFP14647.1 - 1.3e-70 234.0 14.4 4.3e-13 49.6 0.3 6.7 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP14647.1 - 2.7e-62 206.8 0.3 9.7e-12 44.8 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain MAM PF00629.23 KFP14647.1 - 3.2e-50 170.2 0.0 8e-50 168.9 0.0 1.7 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Ig_2 PF13895.6 KFP14647.1 - 4.7e-48 161.4 10.1 5.4e-08 33.1 0.3 6.8 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFP14647.1 - 2.2e-47 159.1 5.4 4.8e-09 36.3 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.17 KFP14647.1 - 8.6e-24 83.8 18.2 0.0033 17.6 0.1 11.8 7 5 1 8 8 8 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP14647.1 - 2.1e-10 40.8 0.0 1.8 9.0 0.0 5.9 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP14647.1 - 3.4e-09 36.8 0.2 0.53 10.6 0.0 5.8 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP14647.1 - 3.7e-09 36.5 3.8 0.28 11.3 0.0 5.4 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP14647.1 - 8e-08 31.7 3.7 0.15 11.7 0.0 5.8 6 0 0 6 6 6 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP14647.1 - 0.00043 20.3 0.4 24 5.0 0.0 5.5 6 0 0 6 6 6 0 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP14647.1 - 0.0037 17.6 3.5 1.2 9.6 0.0 4.8 4 2 0 4 4 4 1 Immunoglobulin C1-set domain CCDC-167 PF15188.6 KFP14648.1 - 3.9e-28 97.6 4.2 4.3e-28 97.5 4.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 FtsJ PF01728.19 KFP14649.1 - 6.2e-38 130.7 0.0 1.2e-37 129.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 KFP14649.1 - 8e-13 48.1 2.3 2.2e-12 46.6 2.3 1.8 1 0 0 1 1 1 1 G-patch domain WW PF00397.26 KFP14649.1 - 0.00017 21.6 1.1 0.00073 19.6 0.0 2.3 2 0 0 2 2 2 1 WW domain mRNA_cap_enzyme PF01331.19 KFP14649.1 - 0.0028 17.5 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 KFP14649.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP dependent DNA ligase domain G-patch_2 PF12656.7 KFP14649.1 - 0.046 13.8 2.6 0.09 12.9 1.6 2.0 2 0 0 2 2 2 0 G-patch domain zf-C3HC4_3 PF13920.6 KFP14650.1 - 7.8e-11 41.7 9.7 1.6e-10 40.7 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP14650.1 - 6.4e-10 38.7 14.3 1.3e-09 37.8 12.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP14650.1 - 6.1e-09 35.6 10.2 6.1e-09 35.6 10.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP14650.1 - 1.2e-08 34.9 9.5 3.7e-08 33.4 7.8 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP14650.1 - 2.6e-08 34.1 12.7 4.4e-08 33.3 11.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP14650.1 - 8.5e-08 32.1 7.1 1.4e-07 31.4 3.5 2.4 1 1 1 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 KFP14650.1 - 4.6e-07 29.7 11.4 4.6e-07 29.7 11.4 2.0 3 0 0 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP14650.1 - 6.6e-07 29.1 9.2 1.5e-06 28.0 9.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP14650.1 - 3.2e-05 24.1 11.2 3.2e-05 24.1 11.2 2.9 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP14650.1 - 0.00036 20.5 4.1 0.0011 19.0 4.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KFP14650.1 - 0.00052 19.8 4.7 0.00096 19.0 4.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFP14650.1 - 0.011 15.8 7.6 0.022 14.9 7.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFP14650.1 - 0.21 11.4 10.2 1.2 8.9 10.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 KFP14650.1 - 0.47 10.5 8.7 1.4 8.9 8.7 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-RING_11 PF17123.5 KFP14650.1 - 1.8 8.4 18.3 2.2 8.1 1.0 2.9 2 1 0 2 2 2 0 RING-like zinc finger zf-C2H2_4 PF13894.6 KFP14650.1 - 4.6 8.4 10.0 14 6.8 0.7 3.4 1 1 2 3 3 3 0 C2H2-type zinc finger FHA PF00498.26 KFP14651.1 - 2.5e-16 59.8 0.0 4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP14651.1 - 1.7e-05 25.0 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LURAP PF14854.6 KFP14651.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein tRNA-synt_2c PF01411.19 KFP14652.1 - 2.4e-132 442.3 0.0 3.2e-132 441.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFP14652.1 - 2.2e-08 34.0 0.9 1.4e-07 31.4 0.1 2.7 3 0 0 3 3 3 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFP14652.1 - 5.9e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 DHHA1 domain HbrB PF08539.11 KFP14652.1 - 0.17 11.9 0.1 1.7 8.6 0.0 2.4 3 0 0 3 3 3 0 HbrB-like LRR_6 PF13516.6 KFP14653.1 - 5.7e-22 75.9 25.2 1.1e-05 25.0 0.5 7.9 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 KFP14653.1 - 1.4e-05 25.0 11.9 1.5 9.6 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 KFP14653.1 - 3.5e-05 23.5 7.9 0.0022 17.7 1.3 5.7 2 1 4 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 KFP14653.1 - 0.0014 19.0 22.2 0.015 15.7 2.4 5.8 3 1 2 6 6 6 1 Leucine Rich repeats (2 copies) GnHR_trans PF12369.8 KFP14653.1 - 0.087 13.6 0.3 0.25 12.2 0.0 1.9 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region TMEM151 PF14857.6 KFP14654.1 - 6.2e-216 717.3 19.1 8.3e-216 716.9 19.1 1.1 1 0 0 1 1 1 1 TMEM151 family Ank_2 PF12796.7 KFP14655.1 - 0.0039 17.7 0.0 0.0085 16.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Kelch_1 PF01344.25 KFP14656.1 - 6.8e-50 166.4 7.6 1.5e-11 43.6 0.0 5.6 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP14656.1 - 2e-30 104.9 1.4 6.8e-30 103.2 0.8 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP14656.1 - 4.2e-29 101.0 0.2 8.2e-29 100.1 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP14656.1 - 6.3e-24 83.4 5.6 2.3e-05 24.5 0.0 5.9 2 1 4 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFP14656.1 - 3.6e-21 74.2 2.6 0.00017 21.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KFP14656.1 - 6.5e-20 70.9 0.8 3e-07 30.3 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP14656.1 - 1.4e-19 69.8 4.3 5.1e-05 23.4 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP14656.1 - 1.5e-13 50.4 6.5 8.5e-07 28.8 0.0 5.3 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 KFP14656.1 - 0.00024 21.2 0.0 0.0017 18.5 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) PFU PF09070.11 KFP14656.1 - 0.027 14.7 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Glyco_hydro_20 PF00728.22 KFP14657.1 - 2.6e-90 303.4 0.0 3.5e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFP14657.1 - 5e-05 24.0 0.0 9.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Ribosomal_S8e PF01201.22 KFP14658.1 - 2.5e-53 179.9 0.3 2.5e-53 179.9 0.3 1.8 1 1 1 2 2 2 1 Ribosomal protein S8e Ank_4 PF13637.6 KFP14660.1 - 1.3e-17 63.9 0.5 3.3e-09 37.1 0.0 3.3 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP14660.1 - 3.5e-15 56.3 0.1 3.4e-09 37.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) RAMA PF18755.1 KFP14660.1 - 3.3e-14 53.2 0.2 1.4e-13 51.2 0.1 2.1 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated Ank PF00023.30 KFP14660.1 - 2.1e-13 50.0 0.1 0.00042 20.6 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP14660.1 - 4.8e-12 45.9 0.3 1.4e-07 31.6 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP14660.1 - 4.3e-08 32.8 0.1 0.16 12.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat AIRS_C PF02769.22 KFP14660.1 - 0.0015 18.7 0.1 0.0072 16.5 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain Cation_ATPase PF13246.6 KFP14660.1 - 0.068 13.3 1.4 21 5.3 0.0 3.6 3 0 0 3 3 3 0 Cation transport ATPase (P-type) Ank_5 PF13857.6 KFP14661.1 - 5.5e-16 58.4 2.4 3.2e-07 30.5 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP14661.1 - 1.4e-14 54.2 0.1 0.00016 22.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP14661.1 - 1.5e-13 50.5 0.1 5.2e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFP14661.1 - 7.8e-13 48.8 0.0 3e-11 43.7 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP14661.1 - 5e-11 41.8 0.1 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat HMG-CoA_red PF00368.18 KFP14662.1 - 1.4e-145 484.9 1.2 1.9e-145 484.5 1.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KFP14662.1 - 7.7e-17 61.5 3.5 1.5e-16 60.6 3.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFP14662.1 - 1.4e-08 33.4 2.2 2.1e-08 32.8 2.2 1.2 1 0 0 1 1 1 1 Patched family Med18 PF09637.10 KFP14663.1 - 1.4e-28 100.4 0.0 1.8e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein IMS PF00817.20 KFP14664.1 - 4.3e-43 146.9 0.1 1.5e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFP14664.1 - 4.4e-17 62.9 1.2 8.8e-17 61.9 0.3 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFP14664.1 - 2.3e-08 33.9 0.1 5e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_12 PF18658.1 KFP14664.1 - 2e-05 24.1 1.7 0.16 11.5 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger C2H2-type ATP-cone PF03477.16 KFP14664.1 - 0.027 15.1 2.0 4.6 7.9 0.5 2.6 2 0 0 2 2 2 0 ATP cone domain Cdd1 PF11731.8 KFP14664.1 - 0.053 13.8 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus zf-Di19 PF05605.12 KFP14664.1 - 0.064 13.6 2.8 11 6.4 0.1 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFP14664.1 - 0.19 12.2 0.3 9.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ank_2 PF12796.7 KFP14665.1 - 2.3e-50 169.1 14.2 6.9e-17 61.8 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP14665.1 - 3.6e-35 119.9 13.3 1.7e-08 34.8 0.1 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP14665.1 - 1.7e-31 104.7 5.7 0.00014 22.0 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP14665.1 - 2.4e-31 107.4 6.9 2.4e-09 37.3 0.3 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP14665.1 - 1.8e-25 88.2 11.4 0.00039 20.7 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Death PF00531.22 KFP14665.1 - 0.021 15.0 2.9 0.036 14.2 1.4 2.1 2 0 0 2 2 2 0 Death domain zf-C4H2 PF10146.9 KFP14666.1 - 0.042 14.2 17.1 0.48 10.7 17.0 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein LidA_Long_CC PF18641.1 KFP14666.1 - 0.066 13.3 0.5 0.066 13.3 0.5 3.1 2 2 1 3 3 3 0 LidA long coiled-coil domain Baculo_PEP_C PF04513.12 KFP14666.1 - 0.26 11.4 1.6 1.3 9.1 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3734 PF12536.8 KFP14666.1 - 0.34 11.3 7.5 1.4 9.3 1.7 2.8 1 1 1 2 2 2 0 Patatin phospholipase CENP-F_leu_zip PF10473.9 KFP14666.1 - 0.34 10.9 17.0 1.5 8.8 7.4 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KFP14666.1 - 0.84 9.9 11.1 1.8 8.8 0.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KFP14666.1 - 1.3 9.1 14.2 2.4 8.3 7.9 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF5082 PF16888.5 KFP14666.1 - 1.4 9.2 11.5 2 8.7 2.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 KFP14666.1 - 5.7 6.8 14.9 0.35 10.7 0.8 3.3 2 1 0 3 3 3 0 Septum formation initiator MFS_1 PF07690.16 KFP14667.1 - 4.3e-35 121.3 31.6 7.7e-25 87.5 15.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP14667.1 - 2.3e-32 112.5 17.6 2.7e-29 102.3 3.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFP14667.1 - 1.1e-06 28.7 8.8 2e-06 27.9 8.8 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KFP14667.1 - 0.00025 21.1 4.9 0.00025 21.1 4.9 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) MFS_4 PF06779.14 KFP14667.1 - 0.00097 18.5 9.4 0.00097 18.5 9.4 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KFP14667.1 - 0.003 16.2 11.7 0.003 16.2 11.7 2.5 2 0 0 2 2 2 1 MFS/sugar transport protein Pentapeptide PF00805.22 KFP14667.1 - 0.05 13.3 1.5 0.2 11.4 0.9 2.1 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) Neurensin PF14927.6 KFP14667.1 - 0.087 12.5 0.3 0.84 9.3 0.0 2.4 2 0 0 2 2 2 0 Neurensin MFS_3 PF05977.13 KFP14667.1 - 0.28 9.5 8.0 0.52 8.6 4.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF1897 PF09005.10 KFP14667.1 - 2.2 7.8 4.2 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) RasGAP PF00616.19 KFP14668.1 - 8.7e-56 188.9 1.4 1.7e-55 188.0 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFP14668.1 - 5.5e-38 130.2 14.6 5.5e-38 130.2 14.6 3.0 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 KFP14668.1 - 2.1e-19 67.4 9.3 0.00024 20.6 0.1 5.1 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.31 KFP14668.1 - 2.8e-16 59.6 0.0 2.3e-15 56.7 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain SHD1 PF03983.12 KFP14668.1 - 0.077 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 7tm_1 PF00001.21 KFP14669.1 - 8.4e-40 136.7 38.6 1.8e-38 132.4 38.6 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP14669.1 - 0.00026 20.7 28.1 0.00026 20.7 28.1 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PRRSV_2b PF07069.11 KFP14669.1 - 0.041 14.4 0.4 0.041 14.4 0.4 3.3 3 1 1 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b S_100 PF01023.19 KFP14670.1 - 1.9e-20 72.3 0.4 2.9e-20 71.7 0.4 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFP14670.1 - 1.5e-06 28.5 0.8 2.2e-06 28.0 0.8 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP14670.1 - 1.6e-06 27.3 1.3 1.7e-05 24.0 0.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP14670.1 - 0.00062 19.5 0.6 0.11 12.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP14670.1 - 0.01 15.7 1.7 0.029 14.2 1.7 2.0 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KFP14670.1 - 0.018 14.5 2.8 0.11 12.0 0.7 2.4 2 0 0 2 2 2 0 EF hand DUF826 PF05696.11 KFP14670.1 - 0.091 12.9 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) CRF-BP PF05428.11 KFP14671.1 - 5.1e-175 580.6 0.1 5.8e-175 580.4 0.1 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) OCRE PF17780.1 KFP14672.1 - 3.2e-18 65.5 14.4 3.2e-18 65.5 14.4 2.8 3 0 0 3 3 3 1 OCRE domain G-patch PF01585.23 KFP14672.1 - 2.9e-14 52.7 5.4 5.5e-14 51.8 5.4 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 KFP14672.1 - 2.3e-13 50.3 0.1 6e-13 48.9 0.1 1.8 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 KFP14672.1 - 6.8e-06 26.1 0.9 6.8e-06 26.1 0.9 2.7 3 0 0 3 3 3 1 G-patch domain Yop-YscD_cpl PF16697.5 KFP14672.1 - 4.2e-05 23.8 0.6 0.00033 20.9 0.0 2.6 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain TFIIA PF03153.13 KFP14672.1 - 0.15 12.0 19.1 0.36 10.8 19.1 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4679 PF15728.5 KFP14672.1 - 1 8.3 4.8 1.9 7.5 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) WD40 PF00400.32 KFP14673.1 - 1.5e-17 63.6 9.5 0.00053 20.7 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14673.1 - 5.1e-05 23.5 1.3 3.9 7.8 0.0 4.1 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP14673.1 - 0.0085 14.9 0.0 0.18 10.5 0.0 2.7 3 0 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 KFP14673.1 - 0.018 13.7 0.0 3.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TBCA PF02970.16 KFP14674.1 - 4.3e-25 87.9 14.3 5e-25 87.6 14.3 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Pkip-1 PF06878.11 KFP14674.1 - 0.03 14.4 4.3 0.04 14.0 4.3 1.2 1 0 0 1 1 1 0 Pkip-1 protein SCAMP PF04144.13 KFP14675.1 - 5.5e-73 245.0 17.3 6.7e-73 244.7 17.3 1.1 1 0 0 1 1 1 1 SCAMP family L_HMGIC_fpl PF10242.9 KFP14676.1 - 1.5e-64 217.6 8.4 1.7e-64 217.4 8.4 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KFP14676.1 - 1.7e-05 24.7 6.2 5e-05 23.2 6.2 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleos_tra2_C PF07662.13 KFP14676.1 - 0.0015 18.5 0.7 0.0015 18.5 0.7 1.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Claudin_3 PF06653.11 KFP14676.1 - 0.0064 16.5 5.1 0.0064 16.5 5.1 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 KFP14676.1 - 0.098 12.5 16.0 0.24 11.2 16.0 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Phage_holin_1 PF04531.13 KFP14676.1 - 1.3 9.6 3.9 6.6 7.3 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage holin RVT_1 PF00078.27 KFP14677.1 - 2.3e-18 66.5 0.0 3.8e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP14677.1 - 0.0054 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase GCV_T PF01571.21 KFP14678.1 - 1.8e-70 237.2 0.0 2.6e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFP14678.1 - 1.1e-63 216.0 0.0 1.6e-63 215.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KFP14678.1 - 2.3e-20 72.3 0.0 5.3e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KFP14678.1 - 7.9e-13 48.5 0.1 1.7e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_3 PF13738.6 KFP14678.1 - 1e-07 31.6 0.0 0.00011 21.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 KFP14678.1 - 7.3e-07 29.4 0.0 1.8e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family FAD_binding_2 PF00890.24 KFP14678.1 - 4.8e-05 22.6 0.2 9.8e-05 21.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFP14678.1 - 8.7e-05 22.7 0.9 0.00063 19.9 0.6 2.4 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFP14678.1 - 0.00043 19.6 0.1 0.00079 18.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFP14678.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP14678.1 - 0.0029 16.9 0.3 0.0048 16.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KFP14678.1 - 0.016 14.9 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFP14678.1 - 0.017 14.1 0.1 0.027 13.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KFP14678.1 - 0.022 15.3 0.2 0.069 13.7 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFP14678.1 - 0.053 13.5 0.1 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFP14678.1 - 0.13 11.0 0.1 0.87 8.2 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein S-methyl_trans PF02574.16 KFP14679.1 - 7e-50 170.3 0.0 8.8e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase WH1 PF00568.23 KFP14680.1 - 4.9e-35 119.8 0.3 9.9e-35 118.8 0.3 1.5 1 0 0 1 1 1 1 WH1 domain DUF812 PF05667.11 KFP14680.1 - 0.00059 18.9 20.4 0.00085 18.3 20.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 KFP14680.1 - 0.00061 20.0 18.6 0.00061 20.0 18.6 2.9 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 KFP14680.1 - 0.00099 18.7 23.1 0.00099 18.7 23.1 1.9 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KFP14680.1 - 0.0027 17.1 18.5 0.0027 17.1 18.5 2.6 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KFP14680.1 - 0.0062 16.6 14.7 0.19 11.8 8.3 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFP14680.1 - 0.014 15.7 7.6 0.014 15.7 7.6 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DMPK_coil PF08826.10 KFP14680.1 - 0.018 15.1 5.1 0.018 15.1 5.1 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like APG6_N PF17675.1 KFP14680.1 - 0.021 15.4 21.8 0.021 15.4 21.8 3.2 1 1 2 4 4 3 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 KFP14680.1 - 0.024 14.5 2.7 0.024 14.5 2.7 3.7 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FUSC PF04632.12 KFP14680.1 - 0.044 12.3 6.6 0.061 11.9 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nsp1_C PF05064.13 KFP14680.1 - 0.054 13.3 22.7 0.48 10.2 10.4 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region IFT57 PF10498.9 KFP14680.1 - 0.094 11.7 26.6 0.22 10.5 26.4 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 KFP14680.1 - 0.16 12.1 37.9 1.5 9.0 20.4 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KFP14680.1 - 0.22 12.0 11.9 0.35 11.4 0.8 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 KFP14680.1 - 0.23 9.6 32.4 0.072 11.3 27.3 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 KFP14680.1 - 0.27 11.2 20.5 0.029 14.4 8.2 2.8 2 1 1 3 3 3 0 Laminin Domain II HemX PF04375.14 KFP14680.1 - 0.51 9.6 24.1 0.15 11.3 9.9 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 KFP14680.1 - 0.54 10.6 23.5 0.062 13.6 12.1 3.4 2 1 0 3 3 2 0 Domain of unknown function (DUF4164) DUF641 PF04859.12 KFP14680.1 - 0.57 10.5 20.2 5.6 7.3 10.0 3.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Prominin PF05478.11 KFP14680.1 - 0.58 8.0 10.2 1.1 7.2 10.2 1.5 1 0 0 1 1 1 0 Prominin Phage_GP20 PF06810.11 KFP14680.1 - 0.61 9.9 24.1 2.3 8.0 14.9 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 CALCOCO1 PF07888.11 KFP14680.1 - 0.67 8.7 32.3 0.085 11.7 26.0 2.4 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.11 KFP14680.1 - 0.74 10.3 16.4 8.5 6.9 1.8 4.3 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.9 KFP14680.1 - 0.85 8.4 16.6 1.4 7.6 15.8 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 KFP14680.1 - 0.91 8.8 19.8 2.1 7.6 19.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KFP14680.1 - 1.5 8.6 33.4 0.37 10.6 4.0 4.5 3 2 1 4 4 3 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KFP14680.1 - 1.6 8.8 36.9 0.11 12.5 26.9 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 KFP14680.1 - 1.7 8.2 27.4 0.49 10.0 3.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DHR10 PF18595.1 KFP14680.1 - 2.4 8.2 41.8 0.79 9.8 20.5 3.5 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain FapA PF03961.13 KFP14680.1 - 2.5 6.6 19.5 19 3.7 19.2 2.2 1 1 0 1 1 1 0 Flagellar Assembly Protein A kleA_kleC PF17383.2 KFP14680.1 - 2.5 8.5 8.5 2.4 8.5 1.4 2.9 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF3461 PF11944.8 KFP14680.1 - 2.7 8.1 15.2 0.24 11.5 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF948 PF06103.11 KFP14680.1 - 2.7 8.3 11.5 12 6.3 3.1 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF489 PF04356.12 KFP14680.1 - 3 7.8 10.6 2.4 8.1 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Leu_zip PF15294.6 KFP14680.1 - 3.1 7.2 27.7 1.2 8.6 24.3 2.1 1 1 0 1 1 1 0 Leucine zipper Bacillus_HBL PF05791.11 KFP14680.1 - 3.3 7.5 19.8 0.71 9.7 5.2 2.7 2 1 1 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) Fzo_mitofusin PF04799.13 KFP14680.1 - 4 7.0 19.9 4.1 6.9 11.6 2.9 1 1 2 3 3 3 0 fzo-like conserved region XhlA PF10779.9 KFP14680.1 - 4.8 7.5 18.4 0.69 10.2 3.4 3.5 2 1 0 3 3 3 0 Haemolysin XhlA FTCD_C PF04961.12 KFP14680.1 - 5.6 6.7 9.6 3.1 7.5 3.7 2.5 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase Fib_alpha PF08702.10 KFP14680.1 - 5.6 7.1 20.6 2.1 8.5 11.3 2.7 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 KFP14680.1 - 7.3 7.0 36.8 0.52 10.7 19.2 3.1 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 KFP14680.1 - 8.5 6.4 35.9 0.22 11.6 12.6 2.7 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.9 KFP14680.1 - 9 7.1 17.2 20 5.9 3.7 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 KFP14680.1 - 9 6.6 32.5 0.27 11.6 17.9 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Lsr2 PF11774.8 KFP14680.1 - 9.8 6.4 7.5 48 4.2 0.0 3.3 2 1 1 3 3 3 0 Lsr2 NAM-associated PF14303.6 KFP14680.1 - 9.8 6.9 17.5 2.2e+02 2.5 17.5 2.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Cluap1 PF10234.9 KFP14680.1 - 9.9 5.5 28.4 3.1 7.1 8.7 2.5 1 1 2 3 3 3 0 Clusterin-associated protein-1 PAP_assoc PF03828.19 KFP14681.1 - 2.2e-15 56.6 0.0 5.3e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFP14681.1 - 0.00049 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain INCA1 PF15142.6 KFP14682.1 - 0.083 12.9 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 INCA1 GST_C_6 PF17171.4 KFP14683.1 - 1.4e-24 85.7 0.9 3.1e-24 84.5 0.3 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP14683.1 - 7.8e-23 81.1 1.0 3.6e-22 79.0 1.0 2.0 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KFP14683.1 - 1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFP14683.1 - 3.5e-07 30.9 0.1 1.7e-06 28.7 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KFP14683.1 - 0.01 16.0 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP14683.1 - 0.018 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TSP_C PF05735.12 KFP14684.1 - 1.3e-98 328.8 1.5 1.8e-98 328.3 1.5 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFP14684.1 - 6.8e-57 188.8 129.2 2.3e-13 49.6 14.7 9.5 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.8 KFP14684.1 - 7.3e-20 71.2 2.9 7.3e-20 71.2 2.9 1.8 2 0 0 2 2 2 1 Cartilage oligomeric matrix protein EGF_CA PF07645.15 KFP14684.1 - 5.3e-13 48.9 40.4 1.6e-08 34.6 5.0 5.2 3 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.7 KFP14684.1 - 1.9e-11 43.7 20.7 0.00021 21.1 0.3 4.5 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF PF00008.27 KFP14684.1 - 7.3e-08 32.6 49.7 2.5e-05 24.5 2.7 5.5 4 1 0 4 4 4 3 EGF-like domain EGF_3 PF12947.7 KFP14684.1 - 5.7e-05 23.2 48.8 0.00084 19.5 3.2 6.1 6 1 1 7 7 7 3 EGF domain Serinc PF03348.15 KFP14685.1 - 1.3e-163 544.9 34.1 1.5e-163 544.7 34.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF5336 PF17270.2 KFP14685.1 - 0.5 10.0 4.0 0.97 9.0 2.9 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5336) DUF3593 PF12159.8 KFP14685.1 - 1.2 9.2 13.8 1.4 9.0 0.1 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF3593) Pkinase PF00069.25 KFP14686.1 - 8.2e-71 238.4 0.0 9.4e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14686.1 - 9.9e-29 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14686.1 - 4.6e-05 22.9 0.1 0.00044 19.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFP14686.1 - 0.0001 21.5 0.1 0.0014 17.7 0.1 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 KFP14686.1 - 0.007 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP14686.1 - 0.03 13.3 0.7 0.087 11.8 0.7 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFP14686.1 - 0.031 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFP14686.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase S36_mt PF10937.8 KFP14687.1 - 0.065 14.8 0.0 0.074 14.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial CENP-H PF05837.12 KFP14688.1 - 8.6e-29 100.2 5.5 8.6e-29 100.2 5.5 1.8 1 1 1 2 2 2 1 Centromere protein H (CENP-H) GldM_N PF12081.8 KFP14688.1 - 0.031 14.4 8.8 0.038 14.1 8.8 1.1 1 0 0 1 1 1 0 GldM N-terminal domain fn3_6 PF17766.1 KFP14688.1 - 0.12 12.6 0.5 0.47 10.7 0.2 2.0 1 1 1 2 2 2 0 Fibronectin type-III domain DUF4202 PF13875.6 KFP14688.1 - 0.23 11.4 6.1 0.25 11.2 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4202) DUF4199 PF13858.6 KFP14688.1 - 1.2 9.5 3.7 0.32 11.4 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Cation_efflux PF01545.21 KFP14689.1 - 1.5e-45 155.4 10.5 1.5e-45 155.4 10.5 3.3 4 1 0 4 4 4 1 Cation efflux family DUF2946 PF11162.8 KFP14689.1 - 3.3 8.4 9.5 11 6.7 9.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) RVT_1 PF00078.27 KFP14690.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PI3K_P85_iSH2 PF16454.5 KFP14692.1 - 1.1e-62 210.4 21.9 2.1e-62 209.5 21.9 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFP14692.1 - 6.7e-43 144.7 0.1 7.5e-22 77.2 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFP14692.1 - 1.2e-30 106.3 3.1 1.3e-30 106.3 0.1 2.3 2 1 0 2 2 2 1 RhoGAP domain AAA_13 PF13166.6 KFP14692.1 - 3e-05 22.9 13.0 4.8e-05 22.2 13.0 1.2 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.6 KFP14692.1 - 0.00029 20.6 13.2 0.0013 18.5 1.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Nucleopor_Nup85 PF07575.13 KFP14692.1 - 0.0033 16.1 0.6 0.0033 16.1 0.6 2.1 2 0 0 2 2 2 1 Nup85 Nucleoporin Laminin_I PF06008.14 KFP14692.1 - 0.0036 17.0 9.6 0.007 16.1 9.6 1.4 1 0 0 1 1 1 1 Laminin Domain I Lant_dehydr_C PF14028.6 KFP14692.1 - 0.0045 16.6 0.7 0.0072 15.9 0.7 1.2 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term Mod_r PF07200.13 KFP14692.1 - 0.014 15.5 19.5 0.43 10.7 3.4 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PI_PP_I PF18363.1 KFP14692.1 - 0.22 11.7 5.1 0.49 10.6 2.3 2.9 2 1 0 2 2 1 0 Phosphoinositide phosphatase insertion domain DUF4806 PF16064.5 KFP14692.1 - 0.84 10.0 4.3 4.7 7.6 0.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4806) Transcrip_act PF04949.13 KFP14692.1 - 0.88 9.4 15.2 0.73 9.7 7.1 3.0 1 1 2 3 3 3 0 Transcriptional activator ANAPC4 PF12896.7 KFP14692.1 - 1.1 8.8 5.9 7.8 5.9 5.9 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Occludin_ELL PF07303.13 KFP14692.1 - 2.1 9.1 20.7 9.7 7.0 3.9 2.9 1 1 1 2 2 2 0 Occludin homology domain Bap31_Bap29_C PF18035.1 KFP14692.1 - 2.7 8.0 6.5 0.81 9.7 0.5 3.0 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2203 PF09969.9 KFP14692.1 - 3.2 8.5 10.2 0.92 10.2 1.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BRE1 PF08647.11 KFP14692.1 - 5.4 7.2 15.4 0.28 11.3 4.0 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Tetraspanin PF00335.20 KFP14693.1 - 9.9e-40 136.7 9.8 1.3e-39 136.3 9.8 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4282 PF14110.6 KFP14693.1 - 8.6 7.2 12.6 12 6.7 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Tetraspanin PF00335.20 KFP14694.1 - 7.4e-15 55.3 3.9 9.3e-15 55.0 3.9 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.6 KFP14694.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Biopterin_H PF00351.21 KFP14695.1 - 1e-177 590.1 0.5 1.3e-177 589.8 0.5 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TOH_N PF12549.8 KFP14695.1 - 6e-22 76.8 1.3 4.5e-12 45.4 0.3 2.7 2 0 0 2 2 2 2 Tyrosine hydroxylase N terminal HSDR_N_2 PF13588.6 KFP14695.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Insulin PF00049.18 KFP14696.1 - 2.1e-24 86.3 1.3 2.7e-24 86.0 1.3 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 KFP14696.1 - 0.032 14.2 5.9 0.45 10.6 0.2 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Ribosomal_L23 PF00276.20 KFP14697.1 - 5.2e-13 49.2 0.9 7.7e-13 48.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpc4 PF05132.14 KFP14697.1 - 0.11 12.9 0.7 0.11 12.9 0.7 1.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Troponin PF00992.20 KFP14698.1 - 2.4e-34 118.5 41.6 2.1e-31 109.0 34.7 2.1 1 1 1 2 2 2 2 Troponin Hid1 PF12722.7 KFP14698.1 - 6.7 4.7 13.0 7.9 4.5 13.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 KFP14698.1 - 8.1 5.0 8.9 9.8 4.7 8.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4643 PF15485.6 KFP14700.1 - 3.2e-42 145.5 30.2 7.6e-42 144.2 30.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4643) Troponin PF00992.20 KFP14701.1 - 6.6e-41 139.8 9.8 1.1e-39 135.8 9.8 2.2 1 1 0 1 1 1 1 Troponin DUF2408 PF10303.9 KFP14701.1 - 0.026 15.1 1.1 0.14 12.7 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4456 PF14644.6 KFP14701.1 - 0.028 14.1 4.6 0.045 13.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) FAM167 PF11652.8 KFP14701.1 - 0.35 11.4 3.4 0.4 11.2 0.2 2.3 2 1 0 2 2 2 0 FAM167 5-nucleotidase PF06189.12 KFP14702.1 - 2.4e-90 302.1 0.0 1e-89 300.0 0.0 1.4 1 1 1 2 2 2 2 5'-nucleotidase Asp PF00026.23 KFP14703.1 - 7.5e-129 429.7 0.0 8.5e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP14703.1 - 3.2e-15 56.8 0.1 1e-07 32.3 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFP14703.1 - 0.0001 22.2 0.0 0.00028 20.7 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFP14703.1 - 0.00012 22.6 0.3 2 9.1 0.1 3.3 2 1 0 2 2 2 2 Aspartyl protease CD225 PF04505.12 KFP14704.1 - 3.4e-21 75.1 0.7 5.3e-21 74.5 0.7 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein TMEM237 PF15383.6 KFP14704.1 - 0.032 13.3 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 ScdA_N PF04405.14 KFP14704.1 - 0.18 11.5 0.6 0.75 9.5 0.2 2.0 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) Mob1_phocein PF03637.17 KFP14705.1 - 3e-59 199.8 5.2 3.7e-59 199.5 5.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family CUE PF02845.16 KFP14706.1 - 1.1e-14 53.8 0.2 2.1e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 CUE domain C2 PF00168.30 KFP14706.1 - 4.8e-14 52.5 0.0 6.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain UBA PF00627.31 KFP14706.1 - 0.00037 20.3 0.1 0.0008 19.3 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.19 KFP14706.1 - 0.068 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family VWD PF00094.25 KFP14707.1 - 3.1e-30 105.5 2.4 3.1e-30 105.5 2.4 2.1 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFP14707.1 - 4.9e-18 65.3 17.2 4.9e-18 65.3 17.2 2.5 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 KFP14707.1 - 6.7e-05 23.1 4.9 6.7e-05 23.1 4.9 4.9 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFP14707.1 - 0.00011 22.5 10.3 0.00011 22.5 10.3 4.7 3 2 1 4 4 4 1 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFP14707.1 - 0.0046 16.6 13.4 0.0046 16.6 13.4 3.7 3 1 0 3 3 3 1 Pacifastin inhibitor (LCMII) VWD PF00094.25 KFP14708.1 - 9.8e-33 113.7 2.8 9.8e-33 113.7 2.8 1.8 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFP14708.1 - 4.7e-19 68.6 16.7 4.7e-19 68.6 16.7 2.2 2 0 0 2 2 2 1 C8 domain VWC PF00093.18 KFP14708.1 - 4.3e-05 23.7 7.8 4.3e-05 23.7 7.8 4.6 4 1 1 5 5 5 1 von Willebrand factor type C domain TIL PF01826.17 KFP14708.1 - 0.00056 20.1 5.7 0.00056 20.1 5.7 5.0 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.25 KFP14709.1 - 3.3e-110 365.4 24.3 5.1e-31 108.1 4.2 4.7 4 0 0 4 4 4 4 von Willebrand factor type D domain C8 PF08742.11 KFP14709.1 - 3.4e-48 161.9 58.0 7e-18 64.8 4.9 9.5 9 1 0 9 9 9 4 C8 domain TIL PF01826.17 KFP14709.1 - 5.3e-20 71.4 55.0 3.1e-13 49.8 15.1 18.2 17 3 4 21 21 21 5 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFP14709.1 - 2.3e-07 31.0 45.3 1.5e-05 25.2 6.4 18.0 14 6 5 19 19 19 7 von Willebrand factor type C domain Pox_ATPase-GT PF10640.9 KFP14709.1 - 0.18 10.7 0.1 0.37 9.6 0.1 1.4 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase VWD PF00094.25 KFP14710.1 - 2.2e-30 106.0 1.7 2.2e-30 106.0 1.7 2.0 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.11 KFP14710.1 - 9.9e-18 64.3 15.6 9.9e-18 64.3 15.6 2.7 2 1 1 3 3 3 1 C8 domain Pacifastin_I PF05375.13 KFP14710.1 - 7e-05 22.5 11.2 7e-05 22.5 11.2 4.3 3 2 0 3 3 3 1 Pacifastin inhibitor (LCMII) TIL PF01826.17 KFP14710.1 - 0.0074 16.5 4.2 0.0074 16.5 4.2 4.8 3 2 1 4 4 4 1 Trypsin Inhibitor like cysteine rich domain Crystall PF00030.19 KFP14710.1 - 0.35 11.1 2.8 4.6 7.5 2.8 2.6 1 1 0 1 1 1 0 Beta/Gamma crystallin VWD PF00094.25 KFP14711.1 - 9.1e-28 97.5 0.4 1.5e-27 96.8 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 KFP14711.1 - 5e-16 58.9 9.8 1.1e-15 57.7 9.8 1.6 1 0 0 1 1 1 1 C8 domain VWD PF00094.25 KFP14712.1 - 3.5e-78 261.3 16.2 1.1e-29 103.8 1.1 3.9 4 0 0 4 4 4 3 von Willebrand factor type D domain C8 PF08742.11 KFP14712.1 - 5.8e-38 129.2 37.3 2.2e-17 63.2 12.2 6.0 5 1 1 6 6 6 3 C8 domain TIL PF01826.17 KFP14712.1 - 5.1e-18 65.1 56.7 5.5e-11 42.6 17.6 9.7 9 2 0 9 9 9 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.18 KFP14712.1 - 2.1e-06 27.9 19.9 5.8e-06 26.5 4.2 9.7 7 4 1 8 8 8 3 von Willebrand factor type C domain DUF3544 PF12064.8 KFP14713.1 - 1.2e-96 323.0 20.4 1.2e-96 323.0 20.4 3.4 4 1 0 4 4 4 1 Protein kinase C-binding protein 1 Bromodomain PF00439.25 KFP14713.1 - 1.9e-16 59.9 0.0 5.9e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFP14713.1 - 8.8e-07 28.7 13.1 8.8e-07 28.7 13.1 3.6 3 0 0 3 3 3 1 PHD-finger PWWP PF00855.17 KFP14713.1 - 2.2e-06 28.0 0.4 2.2e-06 28.0 0.4 2.4 2 0 0 2 2 2 1 PWWP domain DUF1640 PF07798.11 KFP14713.1 - 0.00019 21.5 2.6 0.00019 21.5 2.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1640) zf-MYND PF01753.18 KFP14713.1 - 0.0017 18.4 17.1 0.0017 18.4 17.1 4.1 3 1 0 3 3 3 1 MYND finger Hydrolase PF00702.26 KFP14714.1 - 3.6e-07 30.7 0.0 4.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kdo PF06293.14 KFP14715.1 - 2.4e-08 33.6 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFP14715.1 - 7.9e-06 25.4 0.0 9.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFP14715.1 - 0.00012 22.1 0.1 0.031 14.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 KFP14715.1 - 0.00053 19.4 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 KFP14715.1 - 0.0054 16.1 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFP14715.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KFP14715.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 KFP14715.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Na_sulph_symp PF00939.19 KFP14716.1 - 7.1e-95 318.8 11.3 1.1e-92 311.6 7.0 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP14716.1 - 1.1e-32 113.5 28.5 4e-18 65.6 2.3 3.1 2 1 1 3 3 3 3 Citrate transporter DUF2207 PF09972.9 KFP14716.1 - 0.039 12.7 0.2 0.039 12.7 0.2 2.6 2 2 1 3 3 3 0 Predicted membrane protein (DUF2207) DC_STAMP PF07782.13 KFP14717.1 - 3.9e-37 128.0 2.7 3.9e-37 128.0 2.7 1.8 2 1 0 2 2 2 1 DC-STAMP-like protein DNAP_B_exo_N PF08452.10 KFP14717.1 - 0.32 10.5 2.4 0.71 9.3 2.4 1.6 1 0 0 1 1 1 0 DNA polymerase family B exonuclease domain, N-terminal EI24 PF07264.11 KFP14717.1 - 1.8 8.8 13.0 0.57 10.4 4.1 2.6 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF1981 PF09324.10 KFP14717.1 - 2.8 7.9 4.7 0.81 9.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) 7tm_1 PF00001.21 KFP14718.1 - 3.8e-47 160.8 21.3 4.6e-47 160.6 21.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14718.1 - 3.2e-08 33.3 19.0 7.2e-08 32.1 19.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KFP14718.1 - 7.8e-06 25.4 17.7 0.00027 20.3 0.2 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KFP14718.1 - 3.1e-05 23.8 16.5 3.1e-05 23.8 16.5 2.3 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF776 PF05604.11 KFP14719.1 - 2.8e-69 233.1 11.5 2.8e-69 233.1 11.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF776) DUF776 PF05604.11 KFP14720.1 - 9.8e-57 192.3 4.8 9.8e-57 192.3 4.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF776) SIP1 PF04938.12 KFP14720.1 - 0.008 15.9 0.4 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GST_N_3 PF13417.6 KFP14721.1 - 3.8e-11 43.2 0.0 6.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFP14721.1 - 3.3e-08 33.7 0.0 7.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFP14721.1 - 1.2e-07 31.9 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP14721.1 - 3.4e-05 24.0 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP14721.1 - 3.9e-05 23.6 0.0 0.00013 22.0 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP14721.1 - 0.0027 17.9 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP14721.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Scs3p PF10261.9 KFP14722.1 - 2.6e-20 73.0 17.8 1.3e-12 47.7 5.4 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KFP14722.1 - 4.4e-05 23.3 3.0 4.4e-05 23.3 3.0 2.3 1 1 0 2 2 2 1 PAP2 superfamily Plasmo_rep PF12135.8 KFP14722.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Plasmodium repeat family ARL6IP6 PF15062.6 KFP14722.1 - 0.086 13.0 0.6 0.086 13.0 0.6 2.4 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix DHDPS PF00701.22 KFP14722.1 - 0.088 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family CAP PF00188.26 KFP14723.1 - 3.2e-25 89.4 3.7 4e-25 89.1 3.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M24_C PF16188.5 KFP14723.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 Hormone_recep PF00104.30 KFP14724.1 - 1.3e-40 139.3 0.0 1.8e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP14724.1 - 9.2e-26 90.1 13.5 1.6e-25 89.4 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CRAL_TRIO PF00650.20 KFP14725.1 - 4.8e-33 114.1 0.0 6.6e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP14725.1 - 2.9e-07 30.6 0.5 7.5e-07 29.2 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFP14725.1 - 2.9e-05 24.2 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Serinc PF03348.15 KFP14726.1 - 1.1e-176 588.1 21.9 1.2e-176 587.9 21.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MIG-14_Wnt-bd PF06664.12 KFP14726.1 - 0.5 9.5 30.1 0.38 9.9 1.7 3.2 2 1 0 3 3 3 0 Wnt-binding factor required for Wnt secretion PKI PF02827.16 KFP14727.1 - 2.5e-20 72.4 0.2 2.7e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor TC1 PF15063.6 KFP14727.1 - 0.077 12.9 0.0 0.08 12.8 0.0 1.0 1 0 0 1 1 1 0 Thyroid cancer protein 1 A_deaminase PF00962.22 KFP14728.1 - 1.6e-96 323.5 0.0 1.8e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase IGFBP PF00219.18 KFP14729.1 - 3.5e-10 40.4 19.7 3.5e-10 40.4 19.7 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein VWC PF00093.18 KFP14729.1 - 1e-05 25.7 2.9 1e-05 25.7 2.9 2.9 3 1 0 3 3 3 1 von Willebrand factor type C domain Secapin PF17521.2 KFP14729.1 - 0.077 12.8 7.7 0.15 11.9 7.7 1.4 1 0 0 1 1 1 0 Honey bee peptides 7tm_1 PF00001.21 KFP14730.1 - 8.4e-39 133.5 9.5 1.3e-38 132.9 9.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ion_trans_2 PF07885.16 KFP14731.1 - 1.4e-26 92.2 13.4 1.3e-17 63.5 8.2 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KFP14731.1 - 0.011 14.9 10.3 0.019 14.2 10.3 1.4 1 0 0 1 1 1 0 Ion transport protein C2 PF00168.30 KFP14733.1 - 3.5e-15 56.1 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain 14-3-3 PF00244.20 KFP14734.1 - 1.2e-108 361.7 10.4 1.4e-108 361.6 10.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFP14734.1 - 0.02 14.4 0.3 0.035 13.6 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FliM PF02154.15 KFP14734.1 - 0.051 13.5 0.2 0.087 12.7 0.2 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM SF3A2 PF16835.5 KFP14734.1 - 0.12 12.8 0.4 0.34 11.3 0.2 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF4518 PF15008.6 KFP14734.1 - 0.14 11.4 5.4 3.2 6.8 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Virulence_fact PF13769.6 KFP14734.1 - 1.8 8.8 7.7 0.91 9.8 0.7 2.9 2 1 1 3 3 3 0 Virulence factor YabA PF06156.13 KFP14734.1 - 3.2 8.5 6.6 1.2 9.9 2.6 2.2 3 0 0 3 3 3 0 Initiation control protein YabA RRM_1 PF00076.22 KFP14735.1 - 1.6e-85 280.9 0.4 1.3e-20 73.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFP14735.1 - 2.7e-29 101.1 0.2 6.6e-29 99.9 0.2 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 KFP14735.1 - 0.00029 20.8 0.6 13 5.9 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFP14735.1 - 0.0003 20.9 0.4 10 6.3 0.0 5.0 4 3 0 4 4 4 1 RNA recognition motif SET_assoc PF11767.8 KFP14735.1 - 0.00054 19.6 0.5 8.7 6.1 0.0 4.2 4 0 0 4 4 4 2 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 KFP14735.1 - 0.00062 19.8 2.2 0.79 9.8 0.1 3.8 4 1 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 KFP14735.1 - 0.0017 18.1 0.0 6.3 6.7 0.0 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFP14735.1 - 0.0056 16.7 0.4 20 5.4 0.0 4.0 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.11 KFP14735.1 - 0.097 12.4 5.3 16 5.3 0.2 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Pkinase PF00069.25 KFP14736.1 - 1.4e-64 218.0 0.0 2.1e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14736.1 - 1.4e-46 158.9 0.0 2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 KFP14736.1 - 3.8e-27 94.1 2.6 8.7e-27 93.0 2.6 1.7 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Haspin_kinase PF12330.8 KFP14736.1 - 0.0021 17.1 0.2 0.24 10.3 0.2 2.3 1 1 0 1 1 1 1 Haspin like kinase domain DUF1192 PF06698.11 KFP14736.1 - 0.0037 17.3 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Abi_2 PF07751.11 KFP14736.1 - 0.0059 16.9 1.2 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 Abi-like protein Nore1-SARAH PF16517.5 KFP14736.1 - 1.9 8.5 5.8 0.42 10.6 0.8 2.7 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF4611 PF15387.6 KFP14736.1 - 3.6 7.9 12.2 0.046 13.9 1.8 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) VWA PF00092.28 KFP14737.1 - 6.8e-101 335.8 0.2 6.8e-52 176.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP14737.1 - 2.8e-37 127.6 0.3 1.9e-17 63.9 0.1 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFP14737.1 - 2e-26 92.0 57.7 1.3e-07 31.7 9.2 4.5 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP14737.1 - 1.4e-16 60.4 46.9 8e-05 22.8 3.3 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.7 KFP14737.1 - 2.6e-16 59.2 25.5 1.8e-06 27.8 1.4 5.0 4 0 0 4 4 4 4 Complement Clr-like EGF-like Matrilin_ccoil PF10393.9 KFP14737.1 - 4.7e-12 45.6 1.2 1.2e-11 44.2 1.2 1.7 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin EGF PF00008.27 KFP14737.1 - 1.3e-07 31.7 44.9 0.014 15.7 6.7 4.6 4 0 0 4 4 4 4 EGF-like domain VWA_3 PF13768.6 KFP14737.1 - 2.6e-07 30.7 0.1 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain hEGF PF12661.7 KFP14737.1 - 2.2 9.0 34.7 0.13 12.9 1.5 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_3 PF12947.7 KFP14737.1 - 2.8 8.2 45.3 0.18 12.0 8.0 4.7 4 0 0 4 4 4 0 EGF domain BTD PF09270.10 KFP14738.1 - 8.8e-67 224.1 0.0 1.6e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KFP14738.1 - 1.9e-44 151.9 0.5 5.8e-44 150.4 0.5 1.8 1 1 0 1 1 1 1 LAG1, DNA binding TIG PF01833.24 KFP14738.1 - 0.00076 19.5 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Syndecan PF01034.20 KFP14739.1 - 7.5e-25 86.6 0.2 1.2e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.11 KFP14739.1 - 0.065 13.2 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Beta_helix PF13229.6 KFP14739.1 - 0.078 12.8 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 Right handed beta helix region SYS1 PF09801.9 KFP14740.1 - 2.1e-35 122.0 2.9 2.2e-35 121.9 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network NRN1 PF15056.6 KFP14741.1 - 4.2e-25 87.7 1.1 4.6e-25 87.5 1.1 1.0 1 0 0 1 1 1 1 Neuritin protein family FF PF01846.19 KFP14742.1 - 5.1e-21 74.6 11.2 7.9e-11 42.0 0.9 2.4 2 0 0 2 2 2 2 FF domain WW PF00397.26 KFP14742.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 WW domain WD40 PF00400.32 KFP14743.1 - 1.1e-08 35.6 3.6 5.1 8.1 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14743.1 - 0.00048 20.4 0.0 18 5.7 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Y_phosphatase2 PF03162.13 KFP14743.1 - 0.0093 15.6 0.3 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family BNIP3 PF06553.12 KFP14744.1 - 6.4e-83 277.2 2.4 7.5e-83 277.0 2.4 1.0 1 0 0 1 1 1 1 BNIP3 SIR4_SID PF16991.5 KFP14744.1 - 0.051 13.6 1.2 0.074 13.1 1.2 1.2 1 0 0 1 1 1 0 Sir4 SID domain JAKMIP_CC3 PF16034.5 KFP14745.1 - 9.5e-85 283.6 21.5 9.5e-85 283.6 21.5 6.9 4 2 2 6 6 6 1 JAKMIP CC3 domain Coat_F PF07875.12 KFP14745.1 - 0.48 10.7 5.3 0.1 12.9 0.5 2.5 2 0 0 2 2 2 0 Coat F domain Amidohydro_1 PF01979.20 KFP14746.1 - 9.3e-36 123.8 0.1 1.2e-35 123.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFP14746.1 - 3.6e-10 39.9 0.1 1.9e-06 27.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KFP14746.1 - 0.00073 19.4 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase HPS3_N PF14761.6 KFP14746.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Atg8 PF02991.16 KFP14747.1 - 2.9e-45 152.7 0.4 3.2e-45 152.6 0.4 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFP14747.1 - 2.5e-06 27.8 0.0 3.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cytochrom_B559a PF00284.20 KFP14747.1 - 0.13 12.1 0.1 0.38 10.5 0.1 1.8 1 1 1 2 2 2 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Robl_LC7 PF03259.17 KFP14748.1 - 3.6e-26 90.8 0.0 3.9e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KFP14748.1 - 3.7e-05 23.6 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 KFP14748.1 - 0.061 13.7 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain HECT PF00632.25 KFP14749.1 - 4.6e-98 328.5 0.2 6.6e-98 328.0 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP14749.1 - 2.7e-45 152.1 19.5 7.1e-14 51.6 0.9 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KFP14749.1 - 9.4e-14 51.6 0.5 2.5e-13 50.2 0.5 1.7 1 0 0 1 1 1 1 C2 domain ThuA PF06283.11 KFP14749.1 - 0.69 10.1 2.8 15 5.8 0.7 3.0 2 1 0 2 2 2 0 Trehalose utilisation AdoHcyase PF05221.17 KFP14750.1 - 9.1e-136 451.8 0.0 2.4e-72 243.6 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFP14750.1 - 8.9e-86 286.0 3.1 1.4e-85 285.3 3.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFP14750.1 - 1.7e-09 37.3 0.1 3e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFP14750.1 - 5.6e-06 26.0 0.2 9.5e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFP14750.1 - 0.0014 18.8 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KFP14750.1 - 0.0033 17.3 1.1 0.013 15.4 1.1 2.1 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KFP14750.1 - 0.026 14.2 0.2 0.053 13.2 0.2 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 KFP14750.1 - 0.032 13.0 0.1 1.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.6 KFP14750.1 - 0.085 13.3 0.2 0.23 11.9 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Agouti PF05039.12 KFP14751.1 - 2.2e-17 63.6 14.3 2.4e-17 63.4 13.9 1.3 1 1 0 1 1 1 1 Agouti protein Toxin_9 PF02819.15 KFP14751.1 - 0.98 9.7 17.9 0.26 11.6 15.0 1.5 2 0 0 2 2 2 0 Spider toxin eIF-5_eIF-2B PF01873.17 KFP14752.1 - 1.4e-41 141.0 0.2 2.5e-41 140.2 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 KFP14752.1 - 1.8 9.1 6.8 0.13 12.7 1.0 2.1 2 1 0 2 2 2 0 Cytochrome c3 RRM_1 PF00076.22 KFP14753.1 - 1.5e-12 47.1 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP14753.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKA2 PF16740.5 KFP14753.1 - 0.026 14.3 3.6 1.2 8.9 1.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Ph1570 PF09638.10 KFP14753.1 - 0.067 13.0 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Ph1570 protein Phage_GP20 PF06810.11 KFP14753.1 - 0.25 11.1 5.3 0.41 10.4 5.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Perilipin PF03036.16 KFP14754.1 - 2e-49 168.7 3.1 2.2e-49 168.5 3.1 1.0 1 0 0 1 1 1 1 Perilipin family EspB PF05802.11 KFP14754.1 - 0.00049 20.2 1.2 0.00051 20.1 1.2 1.0 1 0 0 1 1 1 1 Enterobacterial EspB protein Snf7 PF03357.21 KFP14755.1 - 8.4e-46 155.7 8.8 8.4e-46 155.7 8.8 1.9 2 0 0 2 2 2 1 Snf7 SYF2 PF08231.12 KFP14755.1 - 0.0028 18.1 4.1 0.0038 17.6 4.1 1.5 1 1 0 1 1 1 1 SYF2 splicing factor Tim17 PF02466.19 KFP14756.1 - 4.3e-11 43.2 0.1 1e-10 42.0 0.1 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family E2F_CC-MB PF16421.5 KFP14757.1 - 1.6e-20 73.2 0.1 2.5e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain EF-hand_5 PF13202.6 KFP14758.1 - 4.5e-07 29.1 4.2 1.5e-05 24.3 0.9 2.4 1 1 1 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFP14758.1 - 5.8e-06 25.5 2.1 1.1e-05 24.7 0.7 2.1 1 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP14758.1 - 5.9e-06 26.0 0.6 0.0002 21.1 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP14758.1 - 0.00032 20.4 2.1 0.0023 17.7 0.7 2.4 1 1 1 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KFP14758.1 - 0.00067 20.1 0.5 0.0032 17.9 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair ABM PF03992.16 KFP14758.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase HMG_box PF00505.19 KFP14759.1 - 6.2e-11 42.6 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP14759.1 - 2.2e-09 37.8 0.0 4.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 KFP14759.1 - 0.012 16.2 0.5 0.02 15.4 0.5 1.6 1 0 0 1 1 1 0 YABBY protein IMUP PF15761.5 KFP14759.1 - 0.028 15.1 9.4 0.028 15.1 9.4 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Mitofilin PF09731.9 KFP14759.1 - 0.23 10.2 4.2 0.29 9.9 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Glyco_hydro_47 PF01532.20 KFP14760.1 - 3.8e-95 319.5 0.0 6.8e-95 318.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3689 PF12463.8 KFP14761.1 - 2.2e-141 470.7 15.5 3.8e-141 469.9 15.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) GSH_synth_ATP PF03917.17 KFP14763.1 - 7.1e-126 420.0 0.0 8e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFP14763.1 - 1.9e-33 115.0 0.2 4.3e-33 113.8 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MerR_1 PF13411.6 KFP14763.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein AMP-binding PF00501.28 KFP14764.1 - 1.1e-96 324.1 0.0 1.3e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP14764.1 - 2.7e-24 85.9 0.0 6.7e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFP14764.1 - 0.0011 18.8 0.2 0.0033 17.3 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Lectin_leg-like PF03388.13 KFP14765.1 - 4.4e-78 261.8 0.0 6.2e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFP14765.1 - 2.9e-08 34.0 1.7 3.9e-08 33.5 0.3 1.8 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 KFP14765.1 - 0.004 16.7 0.0 0.0092 15.5 0.0 1.7 1 1 0 1 1 1 1 Legume lectin domain DUF3086 PF11285.8 KFP14765.1 - 0.045 12.8 3.4 0.31 10.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) ApoLp-III PF07464.11 KFP14765.1 - 0.32 11.1 7.1 11 6.1 2.3 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.6 KFP14765.1 - 0.33 9.5 4.7 0.45 9.1 4.7 1.1 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.15 KFP14765.1 - 0.43 11.0 5.2 0.37 11.2 1.2 2.8 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF4404 PF14357.6 KFP14765.1 - 0.52 11.0 5.7 6 7.6 0.4 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Mis14 PF08641.12 KFP14765.1 - 0.81 10.0 4.7 1.2 9.4 0.6 2.4 2 0 0 2 2 2 0 Kinetochore protein Mis14 like DUF148 PF02520.17 KFP14765.1 - 0.84 9.8 7.4 4.3 7.5 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 DASH_Dad1 PF08649.10 KFP14765.1 - 1.1 9.5 5.0 0.99 9.6 0.8 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad1 SHE3 PF17078.5 KFP14765.1 - 2.2 8.0 6.1 13 5.4 1.3 2.3 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Synaphin PF05835.12 KFP14766.1 - 1.2e-47 161.7 10.6 1.6e-47 161.4 10.6 1.1 1 0 0 1 1 1 1 Synaphin protein Peptidase_S24 PF00717.23 KFP14767.1 - 5.1e-11 42.4 0.2 8e-11 41.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like zf-C2H2 PF00096.26 KFP14768.1 - 1.7e-22 78.5 120.3 0.0025 18.2 0.5 15.5 15 0 0 15 15 15 11 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KFP14768.1 - 4.6e-17 61.5 72.1 2.2e-16 59.3 3.8 10.2 12 0 0 12 12 12 5 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFP14768.1 - 2.7e-16 58.9 111.8 0.0032 18.2 0.3 15.5 15 0 0 15 15 15 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP14768.1 - 8.7e-07 29.1 0.4 0.00028 21.1 0.1 10.5 14 0 0 14 14 14 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP14768.1 - 5e-06 26.4 0.1 5e-06 26.4 0.1 11.1 12 0 0 12 12 12 3 C2H2-type zinc finger zf-met PF12874.7 KFP14768.1 - 0.00096 19.5 3.2 0.018 15.4 0.3 12.2 14 0 0 14 14 14 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFP14768.1 - 0.0011 19.2 88.4 0.036 14.5 3.0 14.3 16 0 0 16 16 16 5 Zinc-finger double domain DUF3079 PF11278.8 KFP14768.1 - 0.077 12.8 1.2 0.28 11.0 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) zf_ZIC PF18366.1 KFP14768.1 - 0.5 10.5 7.7 2.3 8.4 0.9 3.6 2 1 1 3 3 3 0 Zic proteins zinc finger domain Peptidase_C14 PF00656.22 KFP14769.1 - 6.7e-22 78.6 0.0 1.1e-20 74.6 0.0 1.9 1 1 0 1 1 1 1 Caspase domain Trehalose_PPase PF02358.16 KFP14769.1 - 0.067 12.3 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase CIF PF16374.5 KFP14769.1 - 0.085 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Cycle inhibiting factor (CIF) Alpha_kinase PF02816.18 KFP14770.1 - 7.5e-33 114.2 0.0 1.1e-32 113.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Tsg PF04668.12 KFP14770.1 - 0.0049 17.5 0.3 0.0064 17.2 0.3 1.4 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region HECT PF00632.25 KFP14771.1 - 1.5e-102 343.3 0.0 1.9e-102 342.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP14771.1 - 1.2e-50 169.2 28.2 7.2e-13 48.4 2.9 5.3 5 0 0 5 5 5 4 WW domain C2 PF00168.30 KFP14771.1 - 2.8e-20 72.5 0.0 6.9e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain PhoLip_ATPase_C PF16212.5 KFP14772.1 - 7.8e-80 268.2 24.4 7.8e-80 268.2 24.4 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP14772.1 - 1.5e-25 88.6 5.9 1.5e-25 88.6 5.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFP14772.1 - 6.9e-14 51.7 0.1 4.5e-13 49.1 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP14772.1 - 4.9e-10 40.0 0.6 0.00047 20.5 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP14772.1 - 2.2e-09 37.1 0.5 8e-09 35.3 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP14772.1 - 0.00055 19.7 2.1 0.0018 18.1 0.6 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase FimH_man-bind PF09160.10 KFP14772.1 - 0.043 13.5 0.1 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 FimH, mannose binding Saf_2TM PF18303.1 KFP14772.1 - 0.18 11.4 1.4 0.52 9.9 0.1 2.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ATP-synt_8 PF00895.20 KFP14772.1 - 2.5 8.6 9.3 12 6.4 1.3 3.4 3 0 0 3 3 3 0 ATP synthase protein 8 tRNA-synt_2 PF00152.20 KFP14773.1 - 3.2e-112 374.7 0.0 4.6e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP14773.1 - 2.9e-11 43.2 0.0 5.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 KFP14773.1 - 0.054 13.1 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 tRNA_anti-like DUF1565 PF07602.11 KFP14773.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) tRNA-synt_2d PF01409.20 KFP14773.1 - 0.15 11.5 0.1 7.7 5.9 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Ferrochelatase PF00762.19 KFP14774.1 - 1.3e-110 369.4 0.0 1.5e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Homeodomain PF00046.29 KFP14775.1 - 1.6e-11 43.9 1.2 2.3e-11 43.4 1.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP14775.1 - 1.5e-05 24.8 0.4 2.9e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Homeobox KN domain HOCHOB PF17943.1 KFP14775.1 - 0.032 14.9 0.1 0.049 14.3 0.1 1.2 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox PH_3 PF14593.6 KFP14775.1 - 0.065 13.4 0.6 0.08 13.1 0.6 1.1 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 KFP14776.1 - 3.1e-20 72.1 16.4 0.00019 22.2 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14776.1 - 1.1e-08 35.3 0.0 0.047 14.0 0.0 6.4 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP14776.1 - 0.095 11.6 4.8 2.3 7.1 0.0 3.5 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PITH PF06201.13 KFP14777.1 - 9.1e-41 139.6 0.1 1.3e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFP14777.1 - 1.2e-13 50.9 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFP14777.1 - 0.0086 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Sad1_UNC PF07738.13 KFP14777.1 - 0.0089 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4462 PF14692.6 KFP14778.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ras PF00071.22 KFP14780.1 - 5.4e-55 185.4 0.0 6.9e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14780.1 - 2.3e-32 111.7 0.0 3.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP14780.1 - 3.6e-13 49.3 0.0 5.7e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KFP14780.1 - 9.3e-05 22.2 0.1 0.059 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFP14780.1 - 0.00011 22.1 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP14780.1 - 0.00042 20.4 0.0 0.00085 19.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP14780.1 - 0.0036 16.9 0.0 0.011 15.3 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP14780.1 - 0.012 15.4 0.5 0.21 11.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KFP14780.1 - 0.016 14.4 0.3 3.7 6.6 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP14780.1 - 0.059 12.7 0.1 0.15 11.4 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region CENP-M PF11111.8 KFP14780.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_22 PF13401.6 KFP14780.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.6 1 1 1 2 2 2 0 AAA domain DUF4462 PF14692.6 KFP14782.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP14783.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) zf-CCCH_4 PF18044.1 KFP14784.1 - 1.3e-08 34.4 5.2 2e-08 33.8 5.2 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFP14784.1 - 1.8e-05 24.6 7.0 3e-05 23.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFP14784.1 - 0.00035 20.4 3.2 0.00061 19.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFP14784.1 - 0.0046 17.6 0.0 0.0046 17.6 0.0 2.8 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 KFP14784.1 - 0.52 10.9 6.4 0.85 10.2 6.4 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C2H2 PF00096.26 KFP14785.1 - 3.2e-07 30.5 22.8 0.0057 17.0 3.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP14785.1 - 1e-05 25.9 24.9 0.0042 17.8 1.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP14785.1 - 0.0016 18.7 10.9 0.0016 18.7 10.9 2.4 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 KFP14785.1 - 0.052 13.5 2.2 0.16 11.9 2.2 1.9 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-met PF12874.7 KFP14785.1 - 0.37 11.3 10.8 0.071 13.5 1.8 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 KFP14785.1 - 1.4 8.6 17.8 0.71 9.5 1.5 3.7 2 2 2 4 4 4 0 MYST family zinc finger domain Actin_micro PF17003.5 KFP14785.1 - 5.1 6.2 13.0 3.5 6.7 5.0 2.2 1 1 1 2 2 2 0 Putative actin-like family zf-C2HE PF16278.5 KFP14785.1 - 7.4 7.1 18.6 3.1 8.3 2.1 3.6 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger BEN PF10523.9 KFP14786.1 - 1.9e-08 34.4 0.0 1e-06 28.9 0.0 2.5 2 0 0 2 2 2 1 BEN domain Secretin_N_2 PF07655.13 KFP14786.1 - 3.2 8.4 12.4 11 6.6 2.6 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Carb_anhydrase PF00194.21 KFP14787.1 - 5.2e-86 288.3 0.0 6.1e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Tudor_3 PF18115.1 KFP14787.1 - 0.0099 15.7 0.0 0.23 11.3 0.0 2.7 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain Kelch_4 PF13418.6 KFP14788.1 - 3.3e-39 132.7 0.1 1.7e-11 43.9 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP14788.1 - 3.9e-34 116.3 0.5 9e-08 32.2 0.1 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KFP14788.1 - 1.5e-27 94.9 1.9 7.9e-07 29.2 0.0 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP14788.1 - 1.8e-27 94.8 6.4 1.6e-07 31.1 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFP14788.1 - 1.3e-22 78.8 9.0 3.4e-05 23.6 0.0 7.6 6 3 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFP14788.1 - 3.8e-17 61.6 6.6 1.1e-05 24.9 0.0 7.1 6 1 0 6 6 6 4 Kelch motif DUF4110 PF13422.6 KFP14788.1 - 0.00033 20.7 0.1 0.00033 20.7 0.1 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) CDC45 PF02724.14 KFP14788.1 - 3.5 5.8 8.2 7.9 4.6 8.2 1.5 1 0 0 1 1 1 0 CDC45-like protein SH2 PF00017.24 KFP14789.1 - 1.9e-15 56.7 0.2 2.8e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFP14789.1 - 0.041 13.3 0.0 0.043 13.2 0.0 1.0 1 0 0 1 1 1 0 SH2 domain YqfD PF06898.11 KFP14789.1 - 0.11 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD SIT PF15330.6 KFP14790.1 - 2.8e-28 98.7 0.5 2.8e-28 98.7 0.5 1.6 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT EF-hand_1 PF00036.32 KFP14791.1 - 3.5e-21 73.1 9.4 2.2e-06 26.8 0.0 4.4 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFP14791.1 - 6.1e-20 71.5 1.8 5.2e-14 52.4 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP14791.1 - 5.3e-19 66.5 9.9 1.4e-05 24.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP14791.1 - 2.3e-14 52.1 9.9 2.1e-05 23.8 0.2 4.1 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP14791.1 - 3.8e-13 49.1 4.1 1.3e-06 28.1 0.7 3.1 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP14791.1 - 1.9e-06 28.2 1.4 0.00024 21.4 0.1 3.2 2 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP14791.1 - 0.00013 21.9 6.5 0.15 12.0 0.5 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP14791.1 - 0.0084 16.3 0.3 5.6 7.2 0.1 2.6 1 1 1 2 2 2 2 Dockerin type I domain DUF4891 PF16232.5 KFP14791.1 - 0.037 14.5 0.0 2.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4891) Caleosin PF05042.13 KFP14791.1 - 0.098 12.6 2.8 3.3 7.6 0.1 3.1 1 1 2 3 3 3 0 Caleosin related protein HEAT_2 PF13646.6 KFP14792.1 - 4.9e-14 52.5 0.0 5.3e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.16 KFP14792.1 - 3.5e-12 45.8 0.0 6.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 PBS lyase HEAT-like repeat HEAT PF02985.22 KFP14792.1 - 0.003 17.7 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 3 1 HEAT repeat DDE_Tnp_4 PF13359.6 KFP14793.1 - 4.9e-28 97.8 0.0 6.9e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFP14793.1 - 1.5e-11 44.3 0.0 2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 KFP14793.1 - 3.7e-05 23.4 0.0 7.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KFP14793.1 - 0.0037 16.9 0.0 0.025 14.2 0.0 2.0 1 1 0 1 1 1 1 Transposase DDE domain WD40 PF00400.32 KFP14795.1 - 2.3e-15 56.7 6.3 0.00096 19.9 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP14795.1 - 4.1e-10 39.8 1.4 0.00017 21.9 0.1 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP14795.1 - 0.00013 22.0 0.0 0.058 13.3 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP14795.1 - 0.0052 15.5 0.1 0.011 14.4 0.1 1.6 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP14795.1 - 0.013 14.4 0.0 0.12 11.3 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_2 PF13347.6 KFP14796.1 - 2.2e-16 59.4 10.2 5.1e-16 58.2 10.2 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein Cactin_mid PF10312.9 KFP14797.1 - 5.6e-65 218.8 0.1 1.4e-64 217.5 0.1 1.7 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KFP14797.1 - 8.9e-49 164.6 4.7 1.9e-48 163.6 4.7 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PIP5K PF01504.18 KFP14798.1 - 6.9e-94 314.1 0.0 8.6e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Toxin_33 PF08121.11 KFP14798.1 - 0.2 11.5 0.8 0.39 10.6 0.8 1.5 1 0 0 1 1 1 0 Waglerin family PDZ PF00595.24 KFP14799.1 - 5.2e-44 148.5 2.6 3.7e-15 56.1 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFP14799.1 - 4.8e-24 84.0 0.2 2.2e-10 40.2 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFP14799.1 - 2.4e-20 72.7 0.8 3.4e-08 33.7 0.0 3.5 3 0 0 3 3 3 3 PDZ domain SH3_2 PF07653.17 KFP14799.1 - 8e-11 41.5 0.0 2.3e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Guanylate_kin PF00625.21 KFP14799.1 - 6.3e-10 39.0 0.0 4.1e-09 36.4 0.0 2.0 1 1 1 2 2 2 1 Guanylate kinase SH3_1 PF00018.28 KFP14799.1 - 0.00048 19.7 0.0 0.0013 18.3 0.0 1.9 1 0 0 1 1 1 1 SH3 domain Tricorn_PDZ PF14685.6 KFP14799.1 - 0.0026 17.7 0.1 3.1 7.8 0.0 3.0 3 0 0 3 3 3 2 Tricorn protease PDZ domain PID PF00640.23 KFP14800.1 - 1.8e-44 151.1 0.1 2.8e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFP14800.1 - 3.2e-28 97.9 3.6 7.2e-14 51.9 0.1 2.5 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFP14800.1 - 2.5e-16 59.3 1.2 1.2e-07 31.5 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP14800.1 - 5e-06 26.7 0.0 0.001 19.4 0.0 2.4 2 0 0 2 2 2 1 PDZ domain DUF993 PF06187.11 KFP14800.1 - 0.0041 16.1 0.1 0.006 15.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF993) NRho PF16733.5 KFP14800.1 - 0.025 14.6 0.4 0.082 13.0 0.1 1.9 2 0 0 2 2 2 0 Rhomboid N-terminal domain LysM PF01476.20 KFP14800.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 LysM domain DUF1435 PF07256.12 KFP14800.1 - 0.24 11.5 0.7 0.51 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Pkinase_Tyr PF07714.17 KFP14801.1 - 1.5e-87 293.1 0.0 2e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP14801.1 - 1.1e-46 159.4 0.0 1.7e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP14801.1 - 8e-20 70.7 0.0 1.7e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP14801.1 - 3.4e-09 36.1 0.0 6.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP14801.1 - 2.2e-05 24.2 0.0 6.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP14801.1 - 0.00016 21.2 0.0 0.00038 20.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KFP14801.1 - 0.00043 20.3 0.0 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family SH3_3 PF08239.11 KFP14801.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RIO1 PF01163.22 KFP14801.1 - 0.024 14.2 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFP14801.1 - 0.029 13.3 0.0 0.053 12.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFP14801.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFP14801.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 KFP14802.1 - 1.9e-62 207.0 0.1 1.3e-19 69.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP14802.1 - 2.5e-11 43.2 0.0 0.0014 18.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP14802.1 - 1.2e-05 25.4 0.0 0.04 14.1 0.0 2.9 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_3 PF08777.11 KFP14802.1 - 0.00042 20.3 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KFP14802.1 - 0.0022 17.8 0.0 1.2 9.0 0.0 2.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP14802.1 - 0.0042 17.2 0.0 1.5 9.0 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif E2 PF08199.11 KFP14802.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage E2-like protein SET_assoc PF11767.8 KFP14802.1 - 0.12 12.1 0.0 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated SDF PF00375.18 KFP14803.1 - 3.3e-125 418.1 25.9 3.7e-125 418.0 25.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family hSH3 PF14603.6 KFP14804.1 - 5.7e-27 94.0 0.0 6.7e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KFP14804.1 - 0.00032 20.3 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP14804.1 - 0.038 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KFP14804.1 - 0.055 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Citrate_synt PF00285.21 KFP14805.1 - 3.3e-55 187.6 0.0 5.1e-36 124.5 0.0 3.0 3 0 0 3 3 3 3 Citrate synthase, C-terminal domain UCH_1 PF13423.6 KFP14806.1 - 2.7e-104 349.2 0.1 3.8e-104 348.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KFP14806.1 - 6e-08 32.5 0.7 1e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 KFP14806.1 - 6.8e-05 22.3 0.2 0.00012 21.5 0.2 1.3 1 0 0 1 1 1 1 WD40-like domain PH PF00169.29 KFP14807.1 - 9.7e-13 48.6 0.8 1.1e-12 48.4 0.8 1.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP14807.1 - 4.6e-05 23.8 1.0 5.4e-05 23.6 1.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_15 PF17339.2 KFP14807.1 - 0.051 13.5 0.2 0.058 13.3 0.2 1.3 1 1 0 1 1 1 0 PH domain PH_3 PF14593.6 KFP14807.1 - 0.093 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 PH domain Homeodomain PF00046.29 KFP14808.1 - 1.9e-22 78.8 6.6 2.8e-22 78.3 6.6 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP14808.1 - 0.012 15.5 2.3 0.061 13.2 0.6 2.3 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 KFP14810.1 - 3e-22 78.2 8.4 4.4e-22 77.7 8.4 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFP14810.1 - 0.056 13.8 0.1 0.08 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Terminase_5 PF06056.12 KFP14810.1 - 0.058 13.3 0.3 0.87 9.5 0.2 2.2 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Homeobox_KN PF05920.11 KFP14810.1 - 0.06 13.3 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 Homeobox KN domain NTPase_I-T PF01931.18 KFP14811.1 - 4.4e-09 36.4 0.0 7.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF84 SLC12 PF03522.15 KFP14813.1 - 1.3e-162 541.7 0.1 1.7e-162 541.4 0.1 1.1 1 0 0 1 1 1 1 Solute carrier family 12 AA_permease PF00324.21 KFP14813.1 - 2.2e-148 494.8 39.6 2.6e-148 494.6 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease EGF_CA PF07645.15 KFP14814.1 - 0 1047.7 739.3 4.5e-11 42.8 7.9 48.7 47 1 2 49 49 49 44 Calcium-binding EGF domain cEGF PF12662.7 KFP14814.1 - 4.2e-212 685.2 440.2 3.3e-09 36.5 0.4 51.8 53 0 0 53 53 53 44 Complement Clr-like EGF-like TB PF00683.17 KFP14814.1 - 2.1e-118 385.9 151.6 4.5e-16 58.3 10.8 11.3 9 0 0 9 9 9 9 TB domain EGF PF00008.27 KFP14814.1 - 1.7e-115 376.7 708.5 2.9e-05 24.2 8.2 50.0 49 0 0 49 49 49 45 EGF-like domain FXa_inhibition PF14670.6 KFP14814.1 - 7.3e-94 307.7 736.3 3.6e-08 33.5 9.9 49.8 45 5 5 50 50 50 40 Coagulation Factor Xa inhibitory site hEGF PF12661.7 KFP14814.1 - 3.1e-77 252.8 692.5 0.00047 20.7 6.0 53.7 54 0 0 54 54 54 41 Human growth factor-like EGF EGF_3 PF12947.7 KFP14814.1 - 1.1e-38 131.1 648.2 1.9e-09 37.5 12.6 51.1 47 4 3 50 50 50 37 EGF domain Fibrillin_U_N PF18193.1 KFP14814.1 - 5.5e-18 64.8 7.2 5.5e-18 64.8 7.2 9.1 11 0 0 11 11 11 1 Fibrillin 1 unique N-terminal domain Plasmod_Pvs28 PF06247.11 KFP14814.1 - 0.76 10.1 546.1 0.021 15.1 0.9 46.0 42 5 3 45 45 45 0 Pvs28 EGF domain Frizzled PF01534.17 KFP14818.1 - 3.2e-141 470.1 12.5 3.7e-141 469.9 12.5 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region FxsA PF04186.13 KFP14818.1 - 0.056 13.6 2.8 0.86 9.7 0.0 3.4 3 1 1 4 4 4 0 FxsA cytoplasmic membrane protein Cyclin_N PF00134.23 KFP14819.1 - 8.1e-16 57.9 0.2 1.4e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFP14819.1 - 8.9e-11 42.4 0.2 1.2e-10 42.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin Methyltransf_16 PF10294.9 KFP14820.1 - 1.7e-35 122.3 0.0 2.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP14820.1 - 5.9e-05 23.0 0.0 7.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP14820.1 - 0.00012 21.6 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFP14820.1 - 0.00044 19.8 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFP14820.1 - 0.026 15.2 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFP14820.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain pKID PF02173.17 KFP14821.1 - 1.3e-21 75.8 2.5 3.2e-21 74.5 2.5 1.7 1 0 0 1 1 1 1 pKID domain bZIP_1 PF00170.21 KFP14821.1 - 6.8e-19 67.7 13.5 1.1e-18 67.1 12.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFP14821.1 - 3.9e-07 30.0 13.4 3.9e-07 30.0 13.4 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP14821.1 - 0.0038 17.7 5.7 0.013 16.0 5.7 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor Rh5 PF18515.1 KFP14821.1 - 0.053 12.8 1.8 0.076 12.3 1.8 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain DUF4988 PF16378.5 KFP14821.1 - 0.057 13.1 1.2 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function HNF-1A_C PF04813.12 KFP14821.1 - 0.19 12.5 9.7 0.83 10.5 0.2 2.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus zf-H2C2_2 PF13465.6 KFP14822.1 - 2.7e-09 37.0 10.9 1.7e-05 25.0 0.7 3.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP14822.1 - 6.6e-07 29.5 26.5 0.00013 22.3 0.5 4.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP14822.1 - 0.0079 17.0 19.7 0.057 14.3 0.7 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFP14822.1 - 0.035 14.7 3.6 1.4 9.6 0.4 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP14822.1 - 0.45 10.9 5.9 0.17 12.2 2.6 2.1 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KFP14822.1 - 5.9 6.7 23.7 0.3 10.9 2.1 4.4 4 1 0 4 4 4 0 C2H2-type zinc-finger domain FAST_1 PF06743.15 KFP14823.1 - 1.6e-22 79.2 6.2 1e-21 76.6 0.5 4.0 3 2 2 5 5 5 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFP14823.1 - 4.3e-10 39.5 0.0 8.9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RAP domain FAST_2 PF08368.12 KFP14823.1 - 3.3e-08 34.2 0.1 1.2e-07 32.4 0.1 2.1 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 F-box-like_2 PF13013.6 KFP14823.1 - 0.19 11.7 1.5 3 7.9 1.5 2.8 1 1 0 1 1 1 0 F-box-like domain Ldh_1_C PF02866.18 KFP14824.1 - 2.9e-09 37.1 0.0 6.2e-08 32.7 0.0 2.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFP14824.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain EF-hand_3 PF09069.11 KFP14825.1 - 1.9e-17 63.5 0.0 2.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.11 KFP14825.1 - 0.00029 21.0 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 EF hand Reprolysin PF01421.19 KFP14828.1 - 6.6e-65 218.8 0.1 1.5e-64 217.6 0.1 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFP14828.1 - 2.9e-29 102.1 0.1 7.6e-29 100.7 0.1 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.12 KFP14828.1 - 4e-27 94.9 8.0 4e-27 94.9 8.0 3.4 4 0 0 4 4 4 1 ADAM cysteine-rich Disintegrin PF00200.23 KFP14828.1 - 2.1e-15 57.2 24.9 2.1e-15 57.2 24.9 4.4 4 1 0 4 4 4 1 Disintegrin Reprolysin_5 PF13688.6 KFP14828.1 - 9.8e-08 32.4 0.4 4.3e-07 30.3 0.4 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP14828.1 - 2.1e-07 31.5 0.3 7.1e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KFP14828.1 - 0.00039 20.7 10.5 0.00039 20.7 10.5 6.5 4 3 1 5 5 5 1 EGF-like domain zf-DBF PF07535.12 KFP14829.1 - 3.3e-06 27.1 9.8 3.3e-06 27.1 9.8 1.8 2 0 0 2 2 2 1 DBF zinc finger 7tm_1 PF00001.21 KFP14830.1 - 1.4e-43 149.1 21.7 2e-43 148.6 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP14830.1 - 0.00018 20.9 4.5 0.00018 20.9 4.5 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw EF1_GNE PF00736.19 KFP14831.1 - 1.1e-37 128.1 0.6 2e-37 127.2 0.6 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFP14831.1 - 1.8e-13 50.6 9.7 6.7e-13 48.8 9.7 2.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region YL1 PF05764.13 KFP14831.1 - 0.077 13.1 4.1 0.094 12.8 4.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Molybdopterin PF00384.22 KFP14832.1 - 3.4e-75 253.7 0.0 4.2e-74 250.0 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFP14832.1 - 3.8e-18 65.3 0.3 9.4e-18 64.1 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KFP14832.1 - 5.4e-18 65.4 0.0 1.2e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KFP14832.1 - 2.9e-17 61.9 0.1 7.8e-17 60.5 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KFP14832.1 - 1.3e-09 37.9 0.4 1.3e-09 37.9 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFP14832.1 - 0.075 12.8 0.9 9.8 5.9 0.1 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KFP14832.1 - 0.4 10.6 2.4 16 5.5 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C3Hc3H PF13891.6 KFP14833.1 - 1.6e-17 63.6 5.8 1.6e-17 63.6 5.8 2.3 3 0 0 3 3 3 1 Potential DNA-binding domain RNA_polI_A34 PF08208.11 KFP14836.1 - 0.0046 17.1 20.2 0.0047 17.0 20.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 KFP14836.1 - 0.016 14.9 12.9 0.022 14.4 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.13 KFP14836.1 - 0.023 14.8 16.9 0.025 14.7 16.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 KFP14836.1 - 0.5 8.9 23.4 0.64 8.5 23.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 KFP14836.1 - 1.2 8.9 13.8 1.5 8.6 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 KFP14836.1 - 1.2 8.9 16.7 1.3 8.9 16.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Coilin_N PF15862.5 KFP14836.1 - 1.6 8.5 14.7 2.1 8.1 14.7 1.4 1 1 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 KFP14836.1 - 2.5 6.8 7.7 2.9 6.6 7.7 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KFP14836.1 - 6.4 4.8 8.3 7.6 4.5 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 KFP14836.1 - 6.5 6.4 7.2 7.3 6.3 7.2 1.2 1 0 0 1 1 1 0 Connexin Zip PF02535.22 KFP14836.1 - 9.3 5.4 7.8 11 5.1 7.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PDZ PF00595.24 KFP14837.1 - 6.7e-23 80.9 0.2 1.6e-18 66.8 0.1 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP14837.1 - 5e-14 51.9 0.1 4.3e-10 39.3 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP14837.1 - 3.2e-10 40.2 0.0 1.7e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 PDZ domain V-set_2 PF15910.5 KFP14839.1 - 6.7e-37 126.0 1.7 1.1e-36 125.4 1.7 1.3 1 0 0 1 1 1 1 ICOS V-set domain FAM176 PF14851.6 KFP14839.1 - 0.026 14.2 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 FAM176 family V-set PF07686.17 KFP14840.1 - 1e-12 48.2 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set_2 PF15910.5 KFP14840.1 - 1.5e-11 44.4 0.1 1.9e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 ICOS V-set domain Ig_3 PF13927.6 KFP14840.1 - 0.0072 16.9 0.0 0.014 16.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFP14840.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP14840.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set_2 PF15910.5 KFP14841.1 - 2.3e-10 40.5 0.2 2.3e-10 40.5 0.2 1.7 2 0 0 2 2 2 1 ICOS V-set domain V-set PF07686.17 KFP14841.1 - 5.4e-06 26.6 0.3 5.4e-06 26.6 0.3 1.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain RA PF00788.23 KFP14842.1 - 1.7e-13 51.0 2.8 4.1e-13 49.8 0.3 2.6 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFP14842.1 - 4.6e-11 43.2 0.2 1e-10 42.0 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP14842.1 - 0.0031 17.9 0.7 0.0031 17.9 0.7 2.9 3 2 0 3 3 3 1 Pleckstrin homology domain RBD PF02196.15 KFP14842.1 - 0.0042 17.1 0.1 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Raf-like Ras-binding domain FERM_N PF09379.10 KFP14842.1 - 0.018 15.0 0.2 0.048 13.6 0.2 1.8 1 0 0 1 1 1 0 FERM N-terminal domain p450 PF00067.22 KFP14843.1 - 1.3e-47 162.6 0.1 1.7e-47 162.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S51 PF03575.17 KFP14844.1 - 1.1e-57 195.1 0.0 1.2e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 ID PF18543.1 KFP14844.1 - 0.045 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Intracellular delivery domain Beach PF02138.18 KFP14846.1 - 2.2e-123 411.0 0.3 2.5e-123 410.9 0.3 1.0 1 0 0 1 1 1 1 Beige/BEACH domain NYAP_N PF15439.6 KFP14849.1 - 0.054 12.7 4.1 0.27 10.4 3.6 1.8 1 1 1 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Iso_dh PF00180.20 KFP14850.1 - 1.2e-79 268.0 0.0 1.5e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PIP5K PF01504.18 KFP14851.1 - 1.2e-43 149.3 0.7 5.7e-34 117.6 0.5 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KFP14851.1 - 2.4e-32 112.2 0.3 4e-32 111.5 0.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFP14851.1 - 9.4e-16 57.7 14.0 9.4e-16 57.7 14.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 KFP14851.1 - 1.9e-05 24.6 0.0 5.5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Thioredoxin PF00085.20 KFP14852.1 - 5.3e-95 312.2 0.1 2.9e-24 85.0 0.1 6.0 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.31 KFP14852.1 - 2.9e-24 84.9 2.8 6.4e-24 83.9 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_2 PF13098.6 KFP14852.1 - 1.5e-14 54.4 1.4 0.0003 21.2 0.0 6.5 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP14852.1 - 6.2e-13 48.9 1.0 0.073 13.4 0.0 6.1 4 2 2 6 6 6 3 Thioredoxin-like Thioredoxin_6 PF13848.6 KFP14852.1 - 4.3e-12 46.3 0.0 0.0019 18.2 0.0 3.9 2 2 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 KFP14852.1 - 3.2e-10 39.8 0.1 0.014 14.7 0.0 4.5 3 1 1 4 4 4 4 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFP14852.1 - 1.1e-07 32.0 2.7 1.5 9.1 0.0 4.7 4 0 0 4 4 4 3 Thioredoxin-like Redoxin PF08534.10 KFP14852.1 - 2.5e-07 30.5 2.6 0.13 12.0 0.1 3.6 4 0 0 4 4 4 2 Redoxin AhpC-TSA PF00578.21 KFP14852.1 - 3.6e-07 30.1 2.0 0.69 9.8 0.0 4.7 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_9 PF14595.6 KFP14852.1 - 4.7e-05 23.2 2.4 1.8 8.3 0.1 3.7 2 1 0 3 3 3 2 Thioredoxin TraF PF13728.6 KFP14852.1 - 0.0021 17.9 1.0 0.28 11.0 0.0 3.4 4 0 0 4 4 4 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KFP14852.1 - 0.0068 16.4 0.0 3 8.0 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin domain Calsequestrin PF01216.17 KFP14852.1 - 0.034 13.2 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin RMMBL PF07521.12 KFP14852.1 - 0.055 13.4 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Glyco_hydro_31 PF01055.26 KFP14853.1 - 7.7e-26 91.3 0.0 9.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Ras PF00071.22 KFP14854.1 - 2.6e-21 75.9 0.0 3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14854.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP14855.1 - 2.6e-26 92.2 0.0 2.9e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP14855.1 - 0.00036 20.7 0.0 0.00057 20.1 0.0 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L21p PF00829.21 KFP14858.1 - 5.8e-23 81.1 0.2 8.7e-23 80.5 0.0 1.3 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein RVT_1 PF00078.27 KFP14859.1 - 0.0015 18.1 0.0 0.0039 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_11 PF13086.6 KFP14860.1 - 2.4e-57 194.7 0.3 2.4e-57 194.7 0.3 3.4 4 1 0 4 4 2 1 AAA domain AAA_12 PF13087.6 KFP14860.1 - 1e-51 175.4 0.0 2.2e-51 174.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFP14860.1 - 9.7e-15 54.8 2.4 1.5e-10 41.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain R3H PF01424.22 KFP14860.1 - 1.7e-12 47.2 0.0 5.3e-12 45.5 0.0 1.9 2 0 0 2 2 1 1 R3H domain AAA_19 PF13245.6 KFP14860.1 - 9.5e-12 45.5 0.1 7.7e-11 42.5 0.0 2.5 2 1 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 KFP14860.1 - 3.3e-09 36.9 0.2 0.0011 18.8 0.1 3.5 2 1 0 2 2 2 2 Helicase Viral_helicase1 PF01443.18 KFP14860.1 - 1.3e-07 31.6 0.6 0.3 10.8 0.0 3.9 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KFP14860.1 - 1.1e-06 28.7 0.0 3.9e-06 27.0 0.0 1.9 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 KFP14860.1 - 4.1e-06 26.8 10.9 8.3e-06 25.9 10.9 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger AAA_16 PF13191.6 KFP14860.1 - 0.00023 21.6 0.3 0.00089 19.7 0.3 2.1 1 0 0 1 1 1 1 AAA ATPase domain Flavi_DEAD PF07652.14 KFP14860.1 - 0.00023 21.2 0.1 0.0011 18.9 0.0 2.2 2 0 0 2 2 1 1 Flavivirus DEAD domain AAA_22 PF13401.6 KFP14860.1 - 0.00039 20.7 0.1 0.0022 18.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFP14860.1 - 0.00042 19.9 0.0 0.0028 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KFP14860.1 - 0.00046 20.0 0.2 0.0028 17.5 0.1 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFP14860.1 - 0.00048 19.5 0.4 0.04 13.1 0.4 2.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KFP14860.1 - 0.0024 17.4 0.0 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KFP14860.1 - 0.0034 17.8 0.1 0.011 16.2 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFP14860.1 - 0.0035 16.5 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 KFP14860.1 - 0.013 15.6 0.1 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFP14860.1 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C_2 PF13538.6 KFP14860.1 - 0.035 14.0 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KFP14860.1 - 0.039 13.1 0.0 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase VWA_2 PF13519.6 KFP14860.1 - 0.055 14.1 0.3 3.8 8.2 0.1 3.3 3 0 0 3 3 3 0 von Willebrand factor type A domain ABC_tran PF00005.27 KFP14860.1 - 0.064 13.8 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KFP14860.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CobA_CobO_BtuR PF02572.15 KFP14860.1 - 0.088 13.1 0.1 33 4.7 0.0 3.1 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RL PF17797.1 KFP14860.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 RL domain PhoH PF02562.16 KFP14860.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 KFP14860.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFP14860.1 - 0.14 12.0 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 NTPase Herpes_ori_bp PF02399.15 KFP14860.1 - 0.21 9.6 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein DUF4554 PF15091.6 KFP14860.1 - 0.27 10.1 2.7 0.46 9.3 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) C2 PF00168.30 KFP14861.1 - 3.9e-16 59.2 0.2 5e-11 42.8 0.3 2.7 3 1 0 3 3 3 2 C2 domain PSS PF03034.15 KFP14862.1 - 1.2e-103 346.6 15.3 2.2e-103 345.8 15.3 1.4 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3382 PF11862.8 KFP14862.1 - 0.39 11.0 2.8 2.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF4462 PF14692.6 KFP14863.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP14864.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Anoctamin PF04547.12 KFP14865.1 - 2e-125 419.2 4.7 2.9e-125 418.7 4.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP14865.1 - 2.8e-13 50.1 1.0 1.3e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Cir_Bir_Yir PF06022.11 KFP14865.1 - 0.035 13.6 0.1 0.39 10.2 0.1 2.3 2 0 0 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir PPDFL PF15060.6 KFP14866.1 - 3.6e-30 104.7 1.8 3.9e-30 104.6 1.8 1.0 1 0 0 1 1 1 1 Differentiation and proliferation regulator Pkinase_Tyr PF07714.17 KFP14867.1 - 4.2e-94 314.6 0.0 5.3e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP14867.1 - 2.3e-48 164.9 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP14867.1 - 3.1e-23 81.7 0.0 6.9e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP14867.1 - 1.1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP14867.1 - 2.2e-06 27.2 0.0 4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Haspin_kinase PF12330.8 KFP14867.1 - 6.8e-06 25.3 0.1 1.6e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP14867.1 - 0.0004 20.0 0.1 0.00066 19.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFP14867.1 - 0.0031 16.9 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP14867.1 - 0.011 15.1 0.4 0.026 13.9 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_2 PF07653.17 KFP14867.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain Pkinase_fungal PF17667.1 KFP14867.1 - 0.2 10.4 0.2 0.27 10.0 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase An_peroxidase PF03098.15 KFP14868.1 - 1.8e-198 660.4 0.0 2.5e-198 659.9 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 KFP14868.1 - 6.6e-84 276.1 0.0 1e-20 73.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP14868.1 - 1.8e-70 233.5 0.3 5.1e-17 62.2 0.1 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP14868.1 - 2.9e-48 162.1 0.0 2.5e-11 43.7 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFP14868.1 - 6.9e-36 122.3 0.0 9.5e-09 35.3 0.1 4.5 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.6 KFP14868.1 - 2e-35 120.3 26.7 8.1e-17 60.7 5.4 3.5 1 1 2 3 3 3 3 Leucine rich repeat V-set PF07686.17 KFP14868.1 - 5.3e-24 84.5 5.1 0.00046 20.3 0.2 8.0 4 4 0 4 4 4 4 Immunoglobulin V-set domain LRR_4 PF12799.7 KFP14868.1 - 2.3e-15 56.5 23.0 3.3e-06 27.3 0.8 4.6 6 0 0 6 6 3 3 Leucine Rich repeats (2 copies) C2-set_2 PF08205.12 KFP14868.1 - 4.4e-14 52.3 0.1 0.024 14.7 0.0 4.5 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_5 PF13306.6 KFP14868.1 - 4e-13 49.4 1.2 1.1e-12 48.1 1.2 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_5 PF16681.5 KFP14868.1 - 1e-09 38.6 0.0 0.013 15.8 0.0 4.8 5 0 0 5 5 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_9 PF14580.6 KFP14868.1 - 4.3e-09 36.1 5.6 9.5e-05 22.0 2.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Ig_4 PF16680.5 KFP14868.1 - 4.7e-08 33.2 0.0 0.032 14.5 0.1 4.7 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP14868.1 - 2.6e-05 23.7 0.0 0.24 11.0 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP14868.1 - 6e-05 23.0 0.0 1.4 9.0 0.0 4.6 5 0 0 5 5 5 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP14868.1 - 0.00022 21.2 0.1 21 5.3 0.0 4.6 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain DUF1997 PF09366.10 KFP14868.1 - 0.028 14.5 0.1 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) LRRCT PF01463.24 KFP14868.1 - 0.056 14.0 0.0 0.21 12.2 0.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRRNT PF01462.18 KFP14868.1 - 0.16 11.6 3.3 0.56 9.9 3.3 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain MA-Mit PF09245.10 KFP14868.1 - 0.26 10.7 1.6 0.46 9.9 1.6 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen PCMT PF01135.19 KFP14869.1 - 4.2e-26 92.0 0.0 5.8e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFP14869.1 - 4.8e-05 23.6 6.9 0.098 13.0 0.0 2.5 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFP14869.1 - 0.00019 21.0 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFP14869.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFP14869.1 - 0.016 14.9 0.3 0.031 14.0 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KFP14869.1 - 0.024 15.3 0.0 0.13 13.0 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFP14869.1 - 0.032 15.0 1.1 0.08 13.7 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain REV PF00424.18 KFP14869.1 - 0.038 14.0 0.4 0.074 13.1 0.4 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) HicB_lk_antitox PF15919.5 KFP14869.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system 7tm_1 PF00001.21 KFP14870.1 - 4.7e-64 216.2 17.9 7.3e-64 215.6 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP14870.1 - 9.8e-14 51.3 18.9 1.5e-13 50.7 18.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP14870.1 - 3.7e-08 33.1 7.4 3.7e-08 33.1 7.4 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP14870.1 - 7.3e-08 32.5 16.0 5.5e-07 29.6 16.0 1.9 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP14870.1 - 8.7e-07 28.8 17.9 8.7e-07 28.8 17.9 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4381 PF14316.6 KFP14870.1 - 0.25 11.6 0.0 0.52 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CwfJ_C_1 PF04677.15 KFP14871.1 - 3.7e-25 88.1 0.0 6.3e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 IKBKB_SDD PF18397.1 KFP14872.1 - 8.9e-137 454.9 10.2 1.2e-136 454.5 10.2 1.1 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Pkinase PF00069.25 KFP14872.1 - 1.3e-41 142.8 0.0 2.8e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14872.1 - 8.8e-26 90.7 0.0 2e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.8 KFP14872.1 - 8.7e-16 57.7 4.3 8.7e-16 57.7 4.3 2.5 3 0 0 3 3 3 1 I-kappa-kinase-beta NEMO binding domain Pkinase_fungal PF17667.1 KFP14872.1 - 1.1e-05 24.4 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TBK1_ULD PF18396.1 KFP14872.1 - 0.00015 21.6 0.1 0.00041 20.2 0.0 1.8 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Kdo PF06293.14 KFP14872.1 - 0.00038 19.9 0.0 0.001 18.5 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP14872.1 - 0.0077 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PNMA PF14893.6 KFP14872.1 - 0.0096 15.4 0.6 0.021 14.2 0.6 1.4 1 1 0 1 1 1 1 PNMA DUF3887 PF13026.6 KFP14872.1 - 0.068 14.0 0.5 0.17 12.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) YrbL-PhoP_reg PF10707.9 KFP14872.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Reprolysin PF01421.19 KFP14873.1 - 1.9e-63 214.0 0.0 2.7e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFP14873.1 - 3.6e-24 85.6 0.4 5.8e-24 84.9 0.4 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFP14873.1 - 8.3e-17 62.0 0.0 1.4e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP14873.1 - 8e-14 52.2 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR PF08516.12 KFP14873.1 - 5.3e-11 42.9 3.7 1.5e-10 41.5 3.7 1.8 1 0 0 1 1 1 1 ADAM cysteine-rich Disintegrin PF00200.23 KFP14873.1 - 1.9e-09 38.1 3.7 1.9e-09 38.1 3.7 2.9 2 1 0 2 2 2 1 Disintegrin Reprolysin_2 PF13574.6 KFP14873.1 - 2.8e-09 37.2 0.3 5.5e-09 36.2 0.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP14873.1 - 3.6e-07 30.0 0.0 9.2e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP14873.1 - 0.025 14.4 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 KFP14873.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF3810 PF12725.7 KFP14873.1 - 0.3 10.4 0.2 0.46 9.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) GCP_C_terminal PF04130.13 KFP14874.1 - 1.4e-88 297.3 14.3 1.4e-88 297.3 14.3 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP14874.1 - 1.3e-77 261.5 1.1 1.3e-77 261.5 1.1 2.7 2 1 0 3 3 3 1 Gamma tubulin complex component N-terminal zf-Tim10_DDP PF02953.15 KFP14874.1 - 0.11 12.1 5.7 0.038 13.6 2.4 2.0 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Adaptin_binding PF10199.9 KFP14874.1 - 0.14 12.7 2.0 0.29 11.7 0.3 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF629 PF04780.12 KFP14875.1 - 0.14 10.6 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PRAP PF15314.6 KFP14876.1 - 1.7e-11 44.3 9.3 2.2e-11 44.0 9.3 1.1 1 0 0 1 1 1 1 Proline-rich acidic protein 1, pregnancy-specific uterine MMR_HSR1 PF01926.23 KFP14877.1 - 1.1e-12 48.0 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP14877.1 - 2.2e-06 27.7 0.0 0.0078 16.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFP14877.1 - 7e-06 25.7 0.1 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFP14877.1 - 0.0011 19.4 0.5 0.015 15.7 0.1 2.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFP14877.1 - 0.002 18.4 0.0 0.094 13.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFP14877.1 - 0.003 17.6 0.8 0.35 10.9 0.2 2.2 1 1 1 2 2 2 1 Dynamin family IIGP PF05049.13 KFP14877.1 - 0.0058 15.7 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KFP14877.1 - 0.0065 15.8 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 KFP14877.1 - 0.0068 16.2 0.0 4.2 7.1 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KFP14877.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KFP14877.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFP14877.1 - 0.085 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP14877.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KFP14877.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFP14877.1 - 0.28 10.3 0.0 0.46 9.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Abhydrolase_1 PF00561.20 KFP14878.1 - 5e-21 75.5 0.3 6.8e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP14878.1 - 5e-20 70.8 0.0 1.2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP14878.1 - 4.9e-05 22.7 0.0 0.05 12.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Amino_oxidase PF01593.24 KFP14879.1 - 6.5e-09 35.6 0.0 1.1e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KFP14879.1 - 0.08 12.5 0.0 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase PTEN_C2 PF10409.9 KFP14880.1 - 2e-45 153.8 2.7 3.1e-45 153.3 2.7 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KFP14880.1 - 3.6e-08 33.3 0.0 2.2e-07 30.8 0.0 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP14880.1 - 0.00012 21.7 0.0 0.00032 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP14880.1 - 0.0025 17.8 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP14880.1 - 0.0028 17.8 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate AAA PF00004.29 KFP14881.1 - 1.8e-36 125.5 0.0 5.1e-36 124.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP14881.1 - 3.5e-12 45.9 0.1 7.9e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFP14881.1 - 2e-05 24.4 0.0 7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP14881.1 - 3.3e-05 24.2 0.9 0.081 13.2 0.1 2.9 2 1 1 3 3 3 2 AAA domain TniB PF05621.11 KFP14881.1 - 5.3e-05 22.7 0.3 0.35 10.2 0.0 3.5 3 1 1 4 4 4 1 Bacterial TniB protein AAA_16 PF13191.6 KFP14881.1 - 0.00012 22.5 1.0 0.0022 18.4 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFP14881.1 - 0.00014 21.9 0.1 0.0015 18.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFP14881.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KFP14881.1 - 0.00031 20.4 0.1 0.85 9.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 KFP14881.1 - 0.00061 19.8 0.3 0.0057 16.6 0.3 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KFP14881.1 - 0.0039 16.6 0.1 0.038 13.4 0.1 2.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFP14881.1 - 0.0046 17.5 0.1 0.034 14.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KFP14881.1 - 0.0094 15.5 0.1 0.061 12.8 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFP14881.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFP14881.1 - 0.015 15.4 0.0 0.062 13.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KFP14881.1 - 0.018 14.7 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFP14881.1 - 0.019 14.2 0.0 0.051 12.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KFP14881.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 KFP14881.1 - 0.03 14.1 0.3 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TIP49 PF06068.13 KFP14881.1 - 0.033 13.4 0.0 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 KFP14881.1 - 0.038 13.7 0.1 0.083 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KFP14881.1 - 0.043 13.8 0.1 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 KFP14881.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Sigma54_activ_2 PF14532.6 KFP14881.1 - 0.052 13.7 0.1 0.4 10.8 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KFP14881.1 - 0.054 12.9 0.0 0.92 8.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KFP14881.1 - 0.15 12.3 0.8 3 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFP14881.1 - 0.18 11.2 1.1 0.9 8.8 0.0 2.6 3 1 0 4 4 4 0 KaiC ABC_tran PF00005.27 KFP14881.1 - 0.2 12.2 0.3 1.5 9.4 0.0 2.5 3 1 0 3 3 2 0 ABC transporter AAA_17 PF13207.6 KFP14881.1 - 0.43 11.0 0.0 0.43 11.0 0.0 2.3 3 1 1 4 4 2 0 AAA domain APS_kinase PF01583.20 KFP14882.1 - 1.3e-73 246.1 0.0 2.1e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFP14882.1 - 9e-68 227.9 0.0 1.3e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KFP14882.1 - 8.1e-52 175.1 0.0 1.5e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 KFP14882.1 - 3.6e-05 24.0 0.0 7.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP14882.1 - 0.00016 22.2 0.0 0.0012 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KFP14882.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PAP2_C PF14360.6 KFP14883.1 - 5.1e-29 100.6 14.2 5.1e-29 100.6 14.2 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_3 PF18016.1 KFP14883.1 - 7.9e-07 28.8 0.0 1.9e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFP14883.1 - 6.1e-06 26.1 10.1 6.1e-06 26.1 10.1 1.9 2 1 0 2 2 2 1 PAP2 superfamily SAM_1 PF00536.30 KFP14883.1 - 0.00068 20.0 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.6 KFP14883.1 - 0.0012 18.6 11.2 0.0012 18.6 11.2 2.2 1 1 1 2 2 2 1 PAP2 superfamily SAM_2 PF07647.17 KFP14883.1 - 0.016 15.3 0.1 0.035 14.2 0.1 1.6 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP14883.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.8 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Ceramidase_alk PF04734.13 KFP14884.1 - 3.2e-227 755.2 0.0 3.7e-227 755.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFP14884.1 - 1e-50 171.9 0.3 1.5e-50 171.3 0.3 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RRM_1 PF00076.22 KFP14885.1 - 1.8e-40 136.6 1.6 6.1e-17 61.2 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KFP14885.1 - 4.5e-25 87.7 0.1 1.1e-24 86.5 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PHM7_cyt PF14703.6 KFP14885.1 - 5.1e-05 23.6 0.4 0.65 10.2 0.0 3.7 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KFP14885.1 - 7.2e-05 22.8 0.1 0.89 9.7 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 KFP14885.1 - 0.00036 20.1 0.1 0.49 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP14885.1 - 0.0017 18.4 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 KFP14885.1 - 0.0082 16.0 0.1 7.5 6.5 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif BRAP2 PF07576.12 KFP14885.1 - 0.017 15.3 0.1 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 BRCA1-associated protein 2 SET_assoc PF11767.8 KFP14885.1 - 0.033 13.8 0.1 8 6.2 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated dsrm PF00035.26 KFP14885.1 - 0.06 14.1 0.5 3.2 8.5 0.1 2.9 2 1 0 2 2 2 0 Double-stranded RNA binding motif HEPN_AbiU2 PF18734.1 KFP14885.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 AbiU2 Nup35_RRM_2 PF14605.6 KFP14885.1 - 0.39 10.8 1.3 38 4.4 0.1 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KFP14886.1 - 2.3e-71 240.3 0.0 3.2e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14886.1 - 6.5e-36 123.9 0.0 9.8e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KFP14886.1 - 5.7e-34 116.0 0.1 3.8e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KFP14886.1 - 2.7e-05 23.6 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFP14886.1 - 0.012 15.6 0.0 0.22 11.4 0.0 2.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFP14886.1 - 0.03 15.0 3.7 0.072 13.8 3.7 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Cadherin PF00028.17 KFP14889.1 - 4e-125 408.6 22.4 5.7e-17 61.9 0.0 10.7 10 0 0 10 10 10 10 Cadherin domain ECD PF18432.1 KFP14889.1 - 6.7e-53 177.4 1.5 4.1e-51 171.6 1.1 3.6 3 0 0 3 3 3 1 Extracellular Cadherin domain Cadherin_2 PF08266.12 KFP14889.1 - 8.7e-09 35.1 0.0 0.37 10.6 0.0 5.4 4 0 0 4 4 4 3 Cadherin-like RET_CLD1 PF17756.1 KFP14889.1 - 3.2e-08 33.9 0.0 0.21 11.9 0.0 5.0 6 0 0 6 6 6 2 RET Cadherin like domain 1 DUF3149 PF11346.8 KFP14889.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF4462 PF14692.6 KFP14890.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DUF676 PF05057.14 KFP14891.1 - 6.6e-61 205.6 0.0 1.1e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KFP14891.1 - 4.2e-19 68.8 3.7 6.9e-19 68.2 1.8 2.5 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KFP14891.1 - 2.2e-08 34.2 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFP14891.1 - 2.8e-05 24.0 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFP14891.1 - 0.001 18.4 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1674 PF07896.12 KFP14892.1 - 5.4e-19 68.4 5.3 5.4e-19 68.4 5.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) ArfGap PF01412.18 KFP14893.1 - 6e-33 113.4 0.2 6e-33 113.4 0.2 1.9 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF2151 PF10221.9 KFP14893.1 - 0.01 14.5 2.7 0.016 13.8 2.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Roughex PF06020.11 KFP14893.1 - 0.23 10.5 2.3 1.2 8.1 3.0 1.7 2 0 0 2 2 2 0 Drosophila roughex protein Afi1 PF07792.12 KFP14893.1 - 1.5 9.3 8.6 0.5 10.8 5.7 1.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 KFP14893.1 - 1.7 7.3 4.7 2.8 6.6 4.7 1.3 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 KFP14893.1 - 6.1 6.3 8.9 12 5.3 8.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Glyco_transf_43 PF03360.16 KFP14894.1 - 9.9e-37 126.8 0.1 1.1e-36 126.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Asparaginase_2 PF01112.18 KFP14896.1 - 1.9e-117 391.6 4.5 2.3e-117 391.4 4.5 1.0 1 0 0 1 1 1 1 Asparaginase C2 PF00168.30 KFP14898.1 - 1.3e-39 134.6 0.0 5.1e-19 68.5 0.0 2.8 2 0 0 2 2 2 2 C2 domain PDZ PF00595.24 KFP14898.1 - 5.9e-10 39.4 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP14898.1 - 1.5e-09 37.5 0.0 3.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 KFP14898.1 - 1.2e-07 32.0 7.0 3.6e-07 30.4 7.0 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KFP14898.1 - 8 6.7 11.3 25 5.1 11.3 1.9 1 0 0 1 1 1 0 Piccolo Zn-finger KCNQ_channel PF03520.14 KFP14900.1 - 3.8e-94 313.9 1.5 3.8e-94 313.9 1.5 1.6 2 0 0 2 2 2 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 KFP14900.1 - 2.2e-15 56.6 2.4 3.2e-15 56.0 2.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP14900.1 - 3.9e-14 52.4 5.7 7.1e-14 51.5 5.7 1.4 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.12 KFP14900.1 - 0.18 10.5 0.5 0.28 9.8 0.5 1.2 1 0 0 1 1 1 0 Polycystin cation channel LLC1 PF14945.6 KFP14900.1 - 0.45 11.1 2.7 0.46 11.1 0.3 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DEAD PF00270.29 KFP14901.1 - 1.1e-38 132.8 0.0 2.7e-38 131.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP14901.1 - 7.7e-30 103.5 0.0 2.1e-28 98.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.29 KFP14901.1 - 4.5e-10 39.2 0.4 1.1e-09 38.0 0.1 1.8 2 0 0 2 2 2 1 KH domain MOEP19 PF16005.5 KFP14901.1 - 9.6e-07 28.7 0.0 2.5e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 KH-like RNA-binding domain ResIII PF04851.15 KFP14901.1 - 0.00077 19.5 0.1 0.0034 17.4 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit KH_2 PF07650.17 KFP14901.1 - 0.0079 16.0 0.3 0.041 13.7 0.3 2.2 1 0 0 1 1 1 1 KH domain Mab-21 PF03281.14 KFP14902.1 - 4.2e-76 256.1 3.6 4.7e-76 255.9 3.6 1.0 1 0 0 1 1 1 1 Mab-21 protein GIDA PF01134.22 KFP14903.1 - 9.4e-98 327.8 0.0 1.2e-97 327.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFP14903.1 - 2.9e-65 220.4 0.0 4.2e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain CBAH PF02275.18 KFP14904.1 - 1e-07 31.9 0.0 0.00037 20.2 0.0 2.3 2 0 0 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family SDA1 PF05285.12 KFP14905.1 - 2.6e-67 227.7 42.7 7.3e-38 130.9 5.4 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KFP14905.1 - 8.5e-26 90.0 4.2 1.8e-25 89.0 1.4 3.0 3 0 0 3 3 3 1 NUC130/3NT domain Ribosomal_L22 PF00237.19 KFP14905.1 - 0.015 15.5 2.2 0.03 14.5 0.5 2.4 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e DUF5616 PF18481.1 KFP14905.1 - 0.19 12.1 1.8 28 5.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5616) Ig_J_chain PF15097.6 KFP14907.1 - 1.9e-67 225.2 6.5 2.2e-67 225.1 6.5 1.0 1 0 0 1 1 1 1 Immunoglobulin J chain RUN PF02759.19 KFP14908.1 - 3.1e-32 111.4 4.4 4.1e-32 111.0 0.0 2.6 2 1 0 2 2 2 1 RUN domain Trimer_CC PF08954.11 KFP14908.1 - 0.0035 16.9 6.9 0.11 12.1 0.0 3.2 3 0 0 3 3 3 2 Trimerisation motif ATG16 PF08614.11 KFP14908.1 - 0.034 14.4 29.6 0.069 13.4 29.6 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KFP14908.1 - 0.11 12.6 0.4 0.11 12.6 0.4 5.2 3 2 3 6 6 6 0 bZIP transcription factor KASH_CCD PF14662.6 KFP14908.1 - 0.22 11.3 36.5 0.85 9.4 24.0 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF5595 PF18077.1 KFP14908.1 - 0.48 10.5 14.1 0.58 10.3 0.9 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5595) RRM_1 PF00076.22 KFP14909.1 - 3.5e-17 62.0 0.1 2.4e-06 27.3 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP14909.1 - 0.00038 20.5 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif DPRP PF04244.13 KFP14909.1 - 0.0042 17.0 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Deoxyribodipyrimidine photo-lyase-related protein Mob1_phocein PF03637.17 KFP14910.1 - 2.9e-84 281.2 0.1 3.5e-84 281.0 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family dNK PF01712.19 KFP14911.1 - 4.7e-69 232.3 0.9 5.2e-69 232.2 0.9 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 KFP14911.1 - 0.00056 20.2 0.1 0.0021 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFP14911.1 - 0.0021 17.8 0.0 0.025 14.3 0.0 2.2 2 1 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 KFP14911.1 - 0.01 16.4 0.0 0.081 13.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF5066 PF16728.5 KFP14911.1 - 0.031 13.6 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) AAA_33 PF13671.6 KFP14911.1 - 0.037 14.2 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain HCO3_cotransp PF00955.21 KFP14912.1 - 4.9e-240 797.6 6.0 6.3e-240 797.3 6.0 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP14912.1 - 6.3e-99 331.1 0.6 3.9e-98 328.5 0.6 2.0 1 1 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 KFP14912.1 - 0.00018 21.5 0.0 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 zf-C2H2_4 PF13894.6 KFP14913.1 - 4.3e-63 204.5 191.6 0.00036 21.1 1.7 28.2 28 0 0 28 28 28 25 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP14913.1 - 5.8e-55 180.8 192.6 0.0003 21.1 1.4 27.9 28 0 0 28 28 28 20 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP14913.1 - 8.6e-27 92.6 147.7 1.4e-05 24.9 0.9 24.0 23 1 1 24 24 24 12 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP14913.1 - 1.5e-22 79.0 172.5 0.00027 21.2 2.9 27.1 27 0 0 27 27 27 12 Zinc-finger double domain zf-Di19 PF05605.12 KFP14913.1 - 3.3e-22 78.5 161.6 0.00026 21.2 2.5 18.0 15 4 5 20 20 19 12 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP14913.1 - 3.2e-20 71.9 156.8 0.009 16.3 0.8 25.4 25 2 1 26 26 26 13 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP14913.1 - 6.9e-06 26.3 161.4 0.39 11.1 4.3 22.9 7 4 9 19 19 19 7 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP14913.1 - 7.3e-05 23.4 104.4 0.0011 19.6 8.0 15.8 7 5 8 15 15 15 4 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFP14913.1 - 0.00025 21.3 15.8 0.0022 18.3 2.1 21.3 25 0 0 25 25 24 7 Zinc-finger of C2H2 type C1_4 PF07975.12 KFP14913.1 - 0.027 14.7 0.8 0.027 14.7 0.8 18.5 13 3 8 22 22 21 0 TFIIH C1-like domain Zf_RING PF16744.5 KFP14913.1 - 0.027 14.6 0.6 0.027 14.6 0.6 11.9 14 4 4 18 18 15 0 KIAA1045 RING finger zf-C2H2_9 PF16293.5 KFP14913.1 - 0.083 12.7 0.1 0.083 12.7 0.1 15.9 16 3 3 19 19 19 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFP14913.1 - 0.1 13.1 0.2 0.1 13.1 0.2 13.0 13 0 0 13 13 12 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 KFP14913.1 - 0.28 11.7 0.0 0.099 13.1 0.6 20.5 12 4 8 20 20 19 0 C2HE / C2H2 / C2HC zinc-binding finger Tmemb_18A PF09771.9 KFP14915.1 - 2.8e-56 189.0 0.1 3.1e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 DUF418 PF04235.12 KFP14915.1 - 0.029 14.3 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF35_N PF12172.8 KFP14915.1 - 0.1 12.5 0.0 6.3 6.8 0.0 3.1 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF5392 PF17370.2 KFP14915.1 - 0.19 11.8 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) HEAT_EZ PF13513.6 KFP14916.1 - 2.7e-09 37.3 1.2 2.9e-05 24.5 0.1 4.5 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KFP14916.1 - 5.2e-06 26.8 1.4 0.0091 16.4 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFP14916.1 - 8.5e-06 25.6 8.0 0.43 11.0 0.2 5.5 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 KFP14916.1 - 0.0058 16.6 0.1 0.0058 16.6 0.1 5.7 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFP14916.1 - 0.019 15.0 0.3 0.17 11.9 0.3 2.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KFP14916.1 - 0.029 14.7 0.0 0.13 12.6 0.0 2.2 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Flt3_lig PF02947.14 KFP14916.1 - 0.13 12.5 4.3 9 6.5 0.1 3.6 3 0 0 3 3 3 0 flt3 ligand NTP_transf_2 PF01909.23 KFP14917.1 - 1.9e-16 60.1 0.1 4.4e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KFP14917.1 - 4.7e-15 55.5 0.1 1.5e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KFP14917.1 - 0.00053 20.0 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF3512 PF12024.8 KFP14918.1 - 1.4e-85 286.6 0.1 1.4e-85 286.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFP14918.1 - 9.2e-22 76.9 1.6 2.1e-21 75.8 1.6 1.7 1 0 0 1 1 1 1 Bromodomain DUF2796 PF10986.8 KFP14918.1 - 0.86 9.5 9.1 0.031 14.2 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Vfa1 PF08432.10 KFP14918.1 - 9.8 6.5 24.7 4.5 7.6 10.3 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 EF-hand_7 PF13499.6 KFP14921.1 - 0.0016 18.8 0.0 0.0047 17.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP14921.1 - 0.0029 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KFP14921.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 EF hand Nitroreductase PF00881.24 KFP14921.1 - 0.052 13.6 0.1 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Nitroreductase family PX PF00787.24 KFP14922.1 - 8e-18 64.5 3.6 7.8e-17 61.3 3.8 2.4 3 0 0 3 3 3 1 PX domain TPR_12 PF13424.6 KFP14922.1 - 0.0038 17.5 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF627 PF04781.12 KFP14922.1 - 0.009 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF627) zf-C2H2 PF00096.26 KFP14924.1 - 2.8e-34 115.6 72.9 1.4e-05 25.2 0.2 10.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP14924.1 - 4.9e-34 114.1 72.3 8.7e-05 23.0 0.4 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP14924.1 - 1.4e-25 89.0 39.5 0.00017 21.7 1.4 9.4 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP14924.1 - 4.5e-25 87.2 52.2 0.001 19.4 0.6 9.8 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KFP14924.1 - 7.3e-25 86.3 66.5 4.9e-07 29.9 1.1 11.6 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFP14924.1 - 6.7e-08 32.3 67.9 0.12 12.4 2.0 9.6 10 0 0 10 10 9 7 C2H2-type zinc finger IZUMO PF15005.6 KFP14924.1 - 0.00096 19.7 0.1 0.17 12.4 0.0 2.8 2 0 0 2 2 2 1 Izumo sperm-egg fusion, Ig domain-associated BolA PF01722.18 KFP14924.1 - 0.011 16.0 9.9 1.9 8.8 0.0 5.1 5 0 0 5 5 5 0 BolA-like protein DUF3268 PF11672.8 KFP14924.1 - 0.011 16.1 17.3 0.39 11.1 0.3 4.3 4 0 0 4 4 4 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFP14924.1 - 0.031 14.6 46.5 1.3 9.4 1.0 9.1 5 4 5 10 10 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFP14924.1 - 0.033 14.0 5.4 7.7 6.4 0.2 4.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KFP14924.1 - 0.12 12.7 41.2 0.035 14.4 2.3 5.1 6 0 0 6 6 4 0 Drought induced 19 protein (Di19), zinc-binding Hexapep PF00132.24 KFP14924.1 - 0.12 12.1 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) zf-C2HC_2 PF13913.6 KFP14924.1 - 0.15 12.0 44.2 0.58 10.1 0.1 8.3 9 0 0 9 9 8 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KFP14924.1 - 0.67 9.8 0.0 0.67 9.8 0.0 8.9 10 0 0 10 10 8 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFP14924.1 - 1.4 9.2 30.9 0.31 11.4 1.3 5.7 6 1 0 6 6 5 0 C2H2-type zinc ribbon zf_C2HC_14 PF18574.1 KFP14924.1 - 6.3 6.7 6.6 1.9 8.4 1.5 2.8 2 0 0 2 2 2 0 C2HC Zing finger domain HMG_box PF00505.19 KFP14927.1 - 4.4e-18 65.5 0.5 1.2e-17 64.0 0.5 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP14927.1 - 7.5e-12 45.7 0.8 7.5e-12 45.7 0.8 2.6 2 1 0 2 2 2 1 HMG-box domain YABBY PF04690.13 KFP14927.1 - 0.032 14.8 0.9 0.032 14.8 0.9 3.9 1 1 2 3 3 3 0 YABBY protein IMUP PF15761.5 KFP14927.1 - 5.7 7.7 16.8 0.11 13.2 8.5 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein RB_A PF01858.17 KFP14928.1 - 4.1e-72 242.2 1.0 1e-70 237.6 0.3 2.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFP14928.1 - 5.8e-58 194.6 0.2 2.8e-57 192.4 0.0 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFP14928.1 - 2.4e-48 163.2 0.1 2.4e-48 163.2 0.1 2.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3452) Imm-NTF2 PF15655.6 KFP14928.1 - 0.11 12.8 0.5 0.27 11.5 0.3 1.8 2 0 0 2 2 2 0 NTF2 fold immunity protein DUF4317 PF14199.6 KFP14929.1 - 0.01 15.0 0.7 0.01 15.0 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) UQ_con PF00179.26 KFP14930.1 - 1.4e-22 79.8 0.0 2.4e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme C2-C2_1 PF11618.8 KFP14931.1 - 3.8e-67 224.7 6.7 8.9e-58 194.4 0.3 4.8 5 0 0 5 5 5 2 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 KFP14931.1 - 8.8e-58 194.8 1.0 3.6e-57 192.9 0.3 2.5 2 0 0 2 2 2 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 KFP14931.1 - 2.6e-06 27.7 0.1 1.7e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 C2 domain FTO_NTD PF12933.7 KFP14932.1 - 3.7e-124 413.6 0.0 4.8e-124 413.2 0.0 1.1 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.7 KFP14932.1 - 9.4e-42 142.7 9.2 1.7e-41 141.8 9.2 1.5 1 0 0 1 1 1 1 FTO C-terminal domain FTO_CTD PF12934.7 KFP14934.1 - 1.8e-09 37.6 0.2 2e-09 37.5 0.2 1.0 1 0 0 1 1 1 1 FTO C-terminal domain Ribosomal_L31 PF01197.18 KFP14934.1 - 0.052 13.8 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L31 Homeobox_KN PF05920.11 KFP14935.1 - 2.9e-17 62.3 0.4 4.2e-17 61.7 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP14935.1 - 1.9e-08 34.0 0.4 2.4e-08 33.7 0.4 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFP14935.1 - 0.0076 16.8 1.2 0.0087 16.6 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Homez PF11569.8 KFP14935.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 KFP14937.1 - 1.1e-17 63.6 0.3 1.7e-17 63.0 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP14937.1 - 1.1e-08 34.8 1.9 1.4e-08 34.5 1.9 1.1 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 KFP14937.1 - 0.021 15.4 2.1 0.025 15.1 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homez PF11569.8 KFP14937.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Peptidase_M10 PF00413.24 KFP14938.1 - 1.1e-68 230.1 0.0 3.6e-68 228.4 0.0 1.9 1 1 0 1 1 1 1 Matrixin fn2 PF00040.19 KFP14938.1 - 8.3e-51 170.0 42.2 6.1e-18 64.8 4.4 4.1 4 0 0 4 4 4 3 Fibronectin type II domain Hemopexin PF00045.19 KFP14938.1 - 5.4e-42 141.5 9.6 6.6e-13 48.4 0.6 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP14938.1 - 3.4e-08 33.5 0.0 7.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP14938.1 - 0.009 15.6 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP14938.1 - 0.031 14.8 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP14938.1 - 0.054 13.6 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFP14938.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFP14938.1 - 0.11 11.4 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 EF-hand_1 PF00036.32 KFP14939.1 - 8.4e-19 65.7 12.1 9.9e-06 24.8 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP14939.1 - 1.3e-17 62.1 6.4 2.7e-05 23.8 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFP14939.1 - 3.6e-17 62.6 1.3 5.5e-11 42.8 0.8 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP14939.1 - 1.9e-15 56.4 11.5 3e-10 39.8 1.0 4.0 2 2 1 3 3 3 3 EF-hand domain pair Acyltransferase PF01553.21 KFP14939.1 - 2.1e-13 50.1 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EF-hand_5 PF13202.6 KFP14939.1 - 5.9e-12 44.5 11.1 0.00074 18.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 KFP14939.1 - 0.0012 18.8 3.0 0.57 10.2 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP14939.1 - 0.029 14.7 0.2 0.2 12.0 0.2 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Lipl32 PF12103.8 KFP14939.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order SNF PF00209.18 KFP14940.1 - 5.4e-213 708.4 31.1 6.2e-213 708.2 31.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Peptidase_M19 PF01244.21 KFP14941.1 - 3.1e-105 351.9 0.0 3.5e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ProRS-C_2 PF09181.10 KFP14941.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal 7tm_1 PF00001.21 KFP14942.1 - 3.4e-54 183.9 12.6 4e-54 183.7 12.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP14942.1 - 1.7e-07 30.9 14.0 1.6e-06 27.6 14.0 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFP14942.1 - 4.3e-06 26.3 12.2 5.8e-06 25.9 12.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP14942.1 - 0.00036 20.2 15.3 0.00067 19.4 14.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Abhydrolase_9_N PF15420.6 KFP14942.1 - 0.72 9.8 6.2 0.76 9.7 3.4 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus RHD_dimer PF16179.5 KFP14943.1 - 3.1e-25 88.2 0.2 6.2e-25 87.2 0.2 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFP14943.1 - 9.5e-25 87.5 1.2 5.2e-22 78.6 0.2 3.6 3 1 0 3 3 3 2 Rel homology DNA-binding domain TIG PF01833.24 KFP14943.1 - 8.5e-06 25.8 0.1 5.4e-05 23.2 0.1 2.6 1 1 0 1 1 1 1 IPT/TIG domain RRM_1 PF00076.22 KFP14944.1 - 4.5e-13 48.8 0.0 0.0093 15.8 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFP14944.1 - 0.2 11.9 0.0 26 5.0 0.0 3.0 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Biliv-reduc_cat PF09166.10 KFP14945.1 - 3.1e-58 195.0 0.0 5.3e-58 194.2 0.0 1.4 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.22 KFP14945.1 - 1.6e-17 64.5 0.6 4.3e-17 63.0 0.2 1.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold AlaDh_PNT_C PF01262.21 KFP14945.1 - 0.37 10.1 1.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 KFP14946.1 - 8.6e-70 235.1 0.1 1.3e-69 234.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14946.1 - 7.8e-32 110.6 0.1 1.1e-31 110.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP14946.1 - 6.3e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP14946.1 - 0.00014 21.3 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP14946.1 - 0.046 13.3 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family SPOUT_MTase_2 PF14419.6 KFP14946.1 - 0.049 13.0 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP APH PF01636.23 KFP14946.1 - 0.056 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SRA1 PF07304.11 KFP14946.1 - 0.06 13.1 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Pox_ser-thr_kin PF05445.11 KFP14946.1 - 0.091 11.7 0.1 0.17 10.8 0.1 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase HECT PF00632.25 KFP14948.1 - 5.3e-106 354.6 0.0 7.6e-106 354.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 KFP14948.1 - 3.6e-59 197.8 0.6 7.7e-59 196.7 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFP14948.1 - 7.3e-38 128.5 4.4 8.2e-35 118.7 2.7 2.7 2 0 0 2 2 2 2 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFP14948.1 - 2e-17 63.0 0.5 8.8e-10 38.5 0.5 2.7 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFP14948.1 - 4.9e-11 42.8 0.0 2e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain RFXA_RFXANK_bdg PF15289.6 KFP14948.1 - 7.5 6.9 7.7 1.3 9.3 0.1 3.0 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain Ribosomal_L32p PF01783.23 KFP14949.1 - 2.7e-08 33.9 7.3 4.5e-08 33.2 7.3 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 KFP14949.1 - 0.00027 20.4 0.8 0.00047 19.7 0.8 1.3 1 0 0 1 1 1 1 RecR protein zf-ribbon_3 PF13248.6 KFP14949.1 - 0.056 12.9 1.6 0.12 11.8 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KFP14949.1 - 0.064 13.3 1.9 0.22 11.6 1.3 1.8 1 1 1 2 2 2 0 Double zinc ribbon Proteasome PF00227.26 KFP14950.1 - 2e-60 203.6 0.0 2.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP14950.1 - 6.4e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.15 KFP14950.1 - 0.049 14.0 0.0 6.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF5614 PF18474.1 KFP14951.1 - 1.4e-123 410.4 0.5 2.1e-123 409.8 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5614) DUF1308 PF07000.11 KFP14951.1 - 6.6e-71 237.5 0.0 2.3e-70 235.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) PT PF04886.12 KFP14952.1 - 0.0002 20.8 9.3 0.0002 20.8 9.3 1.8 2 0 0 2 2 2 1 PT repeat TSP_1 PF00090.19 KFP14953.1 - 5.1e-52 173.9 88.6 6.8e-14 51.8 7.2 6.4 6 1 0 6 6 6 5 Thrombospondin type 1 domain GAIN PF16489.5 KFP14953.1 - 1.3e-40 139.1 0.2 1.7e-40 138.7 0.2 1.2 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Syntaxin_2 PF14523.6 KFP14957.1 - 1.5e-22 79.9 9.5 1.5e-22 79.9 9.5 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 KFP14957.1 - 4.9e-08 32.9 15.8 2.3e-06 27.5 11.7 2.7 1 1 1 2 2 2 2 Syntaxin Cauli_AT PF03233.13 KFP14957.1 - 0.06 13.3 6.2 0.13 12.1 0.2 2.3 1 1 0 2 2 2 0 Aphid transmission protein DUF1664 PF07889.12 KFP14957.1 - 0.069 13.2 11.9 2.4 8.2 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KFP14957.1 - 0.13 12.5 12.3 2.6 8.3 0.6 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 KFP14957.1 - 0.17 10.4 3.3 0.27 9.7 1.3 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family 4HB_MCP_1 PF12729.7 KFP14957.1 - 0.19 11.3 5.9 0.055 13.0 1.2 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction HsbA PF12296.8 KFP14957.1 - 0.21 12.0 5.2 3.5 8.1 1.0 3.0 3 0 0 3 3 3 0 Hydrophobic surface binding protein A MCPsignal PF00015.21 KFP14957.1 - 0.32 10.8 11.2 1.6 8.5 1.1 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.13 KFP14957.1 - 0.65 9.2 6.3 1.3 8.2 2.4 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF3037 PF11236.8 KFP14957.1 - 0.82 10.1 3.4 0.81 10.1 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) CENP-H PF05837.12 KFP14957.1 - 1.1 9.7 13.2 0.94 9.9 5.6 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 KFP14957.1 - 1.7 7.5 4.1 2 7.2 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Noelin-1 PF12308.8 KFP14957.1 - 2 8.4 7.7 0.31 11.1 0.5 2.6 2 1 1 3 3 3 0 Neurogenesis glycoprotein Syntaxin-6_N PF09177.11 KFP14957.1 - 2.1 9.0 8.3 2 9.0 3.5 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DASH_Dad1 PF08649.10 KFP14957.1 - 2.2 8.5 7.4 4.8 7.5 0.4 2.8 3 0 0 3 3 2 0 DASH complex subunit Dad1 Fib_alpha PF08702.10 KFP14957.1 - 2.3 8.4 13.4 2 8.6 6.9 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 KFP14957.1 - 2.4 8.2 17.7 0.62 10.1 7.8 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain MCU PF04678.13 KFP14957.1 - 7 6.7 5.9 4.2 7.4 1.3 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4446 PF14584.6 KFP14957.1 - 8.2 6.4 7.8 4.6 7.2 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) GKAP PF03359.13 KFP14962.1 - 3.5e-155 516.8 4.3 3.5e-155 516.8 4.3 3.0 3 0 0 3 3 3 2 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.11 KFP14963.1 - 0.0012 18.7 2.3 0.002 18.0 2.3 1.4 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_1 PF00036.32 KFP14964.1 - 1.2e-13 49.6 12.0 1.3e-07 30.7 1.6 4.5 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 KFP14964.1 - 1.4e-13 51.1 6.5 1.1e-07 32.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP14964.1 - 1.8e-11 43.0 9.4 7.6e-08 31.7 0.9 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFP14964.1 - 3.7e-08 33.1 7.1 0.0025 17.6 0.5 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP14964.1 - 1.6e-05 24.2 4.2 1.8e-05 24.0 1.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFP14964.1 - 2.1e-05 25.3 0.2 0.00075 20.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFP14964.1 - 0.0018 18.2 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFP14964.1 - 0.0024 18.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 KFP14964.1 - 0.016 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Syntaxin PF00804.25 KFP14964.1 - 0.016 14.9 0.2 0.44 10.2 0.1 2.0 2 0 0 2 2 2 0 Syntaxin SurA_N_2 PF13623.6 KFP14964.1 - 0.018 14.9 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFP14964.1 - 0.029 14.7 1.1 0.048 14.0 0.5 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFP14964.1 - 0.045 14.0 0.0 8.6 6.7 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2666 PF10869.8 KFP14964.1 - 0.088 13.0 0.0 0.43 10.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DDE_Tnp_IS66_C PF13817.6 KFP14964.1 - 0.13 12.5 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element EF-hand_1 PF00036.32 KFP14965.1 - 1.2e-13 49.6 12.0 1.3e-07 30.7 1.6 4.5 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 KFP14965.1 - 1.4e-13 51.1 6.5 1.1e-07 32.2 0.1 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP14965.1 - 1.8e-11 43.0 9.4 7.6e-08 31.7 0.9 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KFP14965.1 - 3.7e-08 33.1 7.1 0.0025 17.6 0.5 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP14965.1 - 1.6e-05 24.2 4.2 1.8e-05 24.0 1.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 KFP14965.1 - 2.1e-05 25.3 0.2 0.00075 20.3 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KFP14965.1 - 0.0023 17.9 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.6 KFP14965.1 - 0.0024 18.1 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain GPHH PF16905.5 KFP14965.1 - 0.015 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SurA_N_2 PF13623.6 KFP14965.1 - 0.019 14.8 0.1 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFP14965.1 - 0.027 14.8 0.8 0.049 13.9 0.3 1.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2267 PF10025.9 KFP14965.1 - 0.037 14.3 0.0 8.6 6.7 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) DUF2666 PF10869.8 KFP14965.1 - 0.096 12.9 0.0 0.43 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DDE_Tnp_IS66_C PF13817.6 KFP14965.1 - 0.13 12.5 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 IS66 C-terminal element fn3 PF00041.21 KFP14966.1 - 6.9e-78 257.1 0.1 5.2e-16 58.8 0.0 5.7 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFP14966.1 - 1.5e-73 242.9 13.4 1.2e-20 73.4 0.2 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP14966.1 - 8.9e-47 157.6 8.0 6e-11 42.8 0.1 7.3 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFP14966.1 - 1.3e-36 124.7 5.4 8.7e-09 35.6 0.4 7.2 8 0 0 8 8 7 5 Immunoglobulin domain ig PF00047.25 KFP14966.1 - 3.9e-22 78.2 16.0 0.00012 22.1 0.9 7.8 8 0 0 8 8 7 5 Immunoglobulin domain V-set PF07686.17 KFP14966.1 - 1e-15 57.8 23.1 0.081 13.1 0.0 10.1 7 4 0 7 7 7 5 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP14966.1 - 5.1e-12 46.2 1.9 0.091 13.3 0.0 7.0 7 0 0 7 7 6 4 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP14966.1 - 1.9e-10 40.6 1.2 0.0051 16.9 0.0 4.4 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFP14966.1 - 3.8e-05 23.5 0.0 0.96 9.3 0.0 4.6 5 0 0 5 5 5 2 Tissue factor Interfer-bind PF09294.10 KFP14966.1 - 0.057 13.7 0.0 17 5.8 0.0 3.8 4 0 0 4 4 3 0 Interferon-alpha/beta receptor, fibronectin type III Invasin_D3 PF09134.10 KFP14966.1 - 0.26 11.6 5.3 36 4.8 0.5 4.7 5 0 0 5 5 5 0 Invasin, domain 3 LNS2 PF08235.13 KFP14968.1 - 1.5e-103 345.1 0.0 4.3e-103 343.7 0.0 1.7 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFP14968.1 - 7.7e-45 151.0 0.1 1.5e-44 150.1 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFP14968.1 - 4.1e-34 116.8 0.1 1.1e-33 115.3 0.1 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 KFP14968.1 - 0.0022 18.9 0.2 0.0022 18.9 0.2 3.2 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box Tash_PEST PF07708.11 KFP14968.1 - 6.5 7.1 8.9 0.24 11.6 1.3 2.7 3 0 0 3 3 3 0 Tash protein PEST motif HATPase_c_3 PF13589.6 KFP14969.1 - 3.7e-14 52.7 0.0 6.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFP14969.1 - 9.7e-05 22.8 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Neur_chan_LBD PF02931.23 KFP14970.1 - 4e-37 127.8 3.0 5.4e-37 127.3 3.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP14970.1 - 4.5e-37 128.4 13.5 1e-34 120.7 13.5 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 KFP14970.1 - 0.73 8.0 4.5 1 7.6 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YesK PF14150.6 KFP14970.1 - 1.5 9.0 5.2 11 6.3 0.8 3.2 2 1 1 3 3 3 0 YesK-like protein Neur_chan_LBD PF02931.23 KFP14971.1 - 3.1e-49 167.3 0.0 4.4e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP14971.1 - 7.4e-39 134.2 4.2 1.2e-32 113.9 2.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFP14971.1 - 0.00036 19.7 1.2 0.00048 19.3 1.2 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Neur_chan_memb PF02932.16 KFP14972.1 - 9.8e-51 173.1 0.2 1.8e-50 172.2 0.2 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP14972.1 - 1e-36 126.5 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain OAD_gamma PF04277.13 KFP14972.1 - 0.078 13.6 0.1 0.19 12.3 0.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HECT PF00632.25 KFP14973.1 - 1.1e-93 314.1 0.2 2.5e-93 313.0 0.2 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KFP14973.1 - 5.3e-18 65.0 3.5 1.4e-17 63.6 3.5 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A LPD11 PF18824.1 KFP14973.1 - 0.026 14.6 0.0 9.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 Ion_trans PF00520.31 KFP14974.1 - 4.8e-30 104.6 8.7 6.8e-30 104.1 8.7 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFP14974.1 - 2.1e-29 101.7 4.7 2.1e-29 101.7 4.7 2.9 2 1 0 2 2 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFP14974.1 - 5.7e-19 68.0 0.0 9.8e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CDC45 PF02724.14 KFP14974.1 - 4.6e-05 21.9 2.2 4.6e-05 21.9 2.2 1.8 2 0 0 2 2 2 1 CDC45-like protein Connexin PF00029.19 KFP14974.1 - 0.001 18.9 3.7 0.0022 17.8 3.7 1.5 1 0 0 1 1 1 1 Connexin RR_TM4-6 PF06459.12 KFP14974.1 - 0.0011 18.9 11.9 0.0026 17.6 11.9 1.5 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Med19 PF10278.9 KFP14974.1 - 0.0015 18.5 15.3 0.003 17.5 15.3 1.4 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 CPSF100_C PF13299.6 KFP14974.1 - 0.002 18.3 4.8 0.0057 16.9 4.8 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KFP14974.1 - 0.0062 15.3 2.2 0.01 14.7 2.2 1.2 1 0 0 1 1 1 1 Presenilin DDHD PF02862.17 KFP14974.1 - 0.008 16.4 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 DDHD domain SpoIIIAH PF12685.7 KFP14974.1 - 0.01 15.7 6.8 0.01 15.7 6.8 2.2 3 0 0 3 3 3 0 SpoIIIAH-like protein FancD2 PF14631.6 KFP14974.1 - 0.015 12.8 2.5 0.022 12.2 2.5 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ion_trans_2 PF07885.16 KFP14974.1 - 0.023 14.6 3.6 0.076 13.0 3.6 2.0 1 0 0 1 1 1 0 Ion channel DUF913 PF06025.12 KFP14974.1 - 0.024 13.6 1.6 0.041 12.8 1.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 KFP14974.1 - 0.048 13.1 14.8 0.097 12.1 14.8 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 KFP14974.1 - 0.048 12.4 9.6 0.078 11.8 9.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 KFP14974.1 - 0.053 14.0 11.7 0.11 12.9 11.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 KFP14974.1 - 0.07 12.9 23.0 0.037 13.8 17.9 2.4 2 0 0 2 2 2 0 Coilin N-terminus AAA_23 PF13476.6 KFP14974.1 - 0.072 13.6 16.9 0.058 13.9 11.1 2.5 2 0 0 2 2 2 0 AAA domain SAPS PF04499.15 KFP14974.1 - 0.076 11.8 4.9 0.11 11.2 4.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2151 PF10221.9 KFP14974.1 - 0.43 9.1 8.8 0.66 8.5 8.8 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Neur_chan_memb PF02932.16 KFP14974.1 - 0.5 10.4 3.0 1.8 8.6 2.2 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3043 PF11241.8 KFP14974.1 - 0.52 10.3 2.3 1.3 9.0 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CSRNP_N PF16019.5 KFP14974.1 - 0.56 10.1 7.7 1.2 9.0 7.7 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4820 PF16091.5 KFP14974.1 - 0.6 9.4 6.9 1.2 8.5 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM76 PF16046.5 KFP14974.1 - 0.61 9.4 20.9 0.5 9.7 0.2 2.3 2 0 0 2 2 2 0 FAM76 protein DUF2828 PF11443.8 KFP14974.1 - 1.1 7.3 11.3 1.7 6.7 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TMEM214 PF10151.9 KFP14974.1 - 1.2 7.6 14.8 1.8 6.9 14.8 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator PTPRCAP PF15713.5 KFP14974.1 - 1.4 9.2 15.4 3.2 8.0 15.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4614 PF15391.6 KFP14974.1 - 1.4 8.9 8.1 4 7.4 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Tim54 PF11711.8 KFP14974.1 - 1.5 7.5 16.3 2.7 6.7 16.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.12 KFP14974.1 - 1.9 8.7 10.0 0.26 11.5 5.9 1.6 2 0 0 2 2 1 0 GAGA binding protein-like family Zip PF02535.22 KFP14974.1 - 2.2 7.4 6.9 3.6 6.7 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.6 KFP14974.1 - 2.4 7.9 11.4 0.42 10.4 7.1 1.9 2 0 0 2 2 2 0 AAA domain DUF1980 PF09323.10 KFP14974.1 - 4.5 7.1 7.5 21 5.0 7.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CLN3 PF02487.17 KFP14974.1 - 4.5 6.2 5.4 7.9 5.4 5.4 1.3 1 0 0 1 1 1 0 CLN3 protein Afi1 PF07792.12 KFP14974.1 - 6.2 7.3 20.2 3 8.3 16.8 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sec62 PF03839.16 KFP14974.1 - 7.3 6.0 22.8 0.6 9.6 14.6 2.5 2 0 0 2 2 2 0 Translocation protein Sec62 MMU163 PF17119.5 KFP14974.1 - 7.3 5.7 8.8 63 2.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis TRAP_alpha PF03896.16 KFP14974.1 - 8 5.6 12.4 15 4.7 12.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NARP1 PF12569.8 KFP14974.1 - 9.1 5.1 28.9 0.088 11.7 20.2 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 PPL5 PF18168.1 KFP14974.1 - 9.3 5.4 13.0 17 4.6 13.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF5523 PF17661.1 KFP14974.1 - 9.5 5.8 27.0 0.21 11.2 19.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5523) VWA_3 PF13768.6 KFP14975.1 - 0.0068 16.4 0.5 0.0093 15.9 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TMEM131_like PF12371.8 KFP14976.1 - 1e-23 83.4 8.6 2.3e-23 82.2 0.8 4.5 4 0 0 4 4 4 1 Transmembrane protein 131-like ASH PF15780.5 KFP14976.1 - 1.1e-11 44.8 3.2 0.00093 19.4 0.2 7.2 7 0 0 7 7 7 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin C2 PF00168.30 KFP14977.1 - 0.003 17.8 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain NHR2 PF08788.11 KFP14977.1 - 0.0066 16.2 0.5 0.21 11.4 0.2 2.7 2 0 0 2 2 2 1 NHR2 domain like UNC-50 PF05216.13 KFP14978.1 - 4.8e-91 304.2 22.9 5.5e-91 304.0 22.9 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_transf_54 PF04666.13 KFP14979.1 - 4.1e-136 452.5 1.5 5.7e-136 452.1 1.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3775 PF12616.8 KFP14979.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Pkinase PF00069.25 KFP14980.1 - 4e-56 190.3 0.0 5.3e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP14980.1 - 8.5e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP14980.1 - 2.4e-05 23.3 0.0 2.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PB1 PF00564.24 KFP14980.1 - 7e-05 22.7 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFP14980.1 - 0.00032 20.1 0.0 0.00073 18.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP14980.1 - 0.00038 19.5 0.0 0.024 13.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP14980.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Adaptin_binding PF10199.9 KFP14981.1 - 1.7e-19 70.6 2.4 2.4e-19 70.1 2.4 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 KFP14981.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Ras family MH2 PF03166.14 KFP14982.1 - 1.5e-79 266.6 0.1 1.9e-79 266.2 0.1 1.1 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP14982.1 - 9.7e-29 99.6 2.3 2.1e-28 98.6 2.3 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP14982.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH1 PF03165.16 KFP14983.1 - 7.2e-05 22.9 0.7 0.0001 22.5 0.7 1.2 1 0 0 1 1 1 1 MH1 domain MH2 PF03166.14 KFP14984.1 - 1.2e-56 191.8 0.0 1.4e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 MH2 domain Glyco_hydro_31 PF01055.26 KFP14985.1 - 5.1e-206 685.0 2.7 3e-146 488.1 2.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFP14985.1 - 7.1e-65 216.4 3.3 1.9e-32 111.9 0.2 2.5 2 0 0 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KFP14985.1 - 3.4e-15 55.6 16.5 4.2e-08 32.9 2.1 2.7 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KFP14985.1 - 8e-10 38.9 5.8 1.6e-05 25.1 1.2 2.9 2 0 0 2 2 2 2 Galactose mutarotase-like RRM_1 PF00076.22 KFP14986.1 - 4.4e-06 26.4 0.0 9.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP14986.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PRP38_assoc PF12871.7 KFP14986.1 - 8.7 7.0 37.6 1.4 9.6 33.2 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Transmemb_17 PF09799.9 KFP14987.1 - 3.7e-09 37.1 1.6 4.8e-09 36.8 1.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein TMEM138 PF14935.6 KFP14988.1 - 2.6e-20 73.2 11.8 2.6e-20 73.2 11.8 1.5 2 0 0 2 2 2 1 Transmembrane protein 138 MMS1_N PF10433.9 KFP14989.1 - 1.9e-118 396.2 0.0 4.8e-118 394.9 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFP14989.1 - 6.5e-80 268.8 0.1 5.9e-79 265.7 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region Choline_transpo PF04515.12 KFP14990.1 - 9.8e-71 238.6 42.8 4e-52 177.4 15.3 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter PAS_3 PF08447.12 KFP14992.1 - 3.2e-19 69.0 0.1 8e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP14992.1 - 1.2e-14 54.4 0.9 7.5e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KFP14992.1 - 1e-12 48.0 2.7 1.3e-11 44.5 0.0 2.9 3 0 0 3 3 3 1 PAS fold HLH PF00010.26 KFP14992.1 - 6.2e-06 26.1 0.2 1.4e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 KFP14992.1 - 0.0098 16.1 2.5 0.092 13.0 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KFP14992.1 - 0.013 15.7 0.1 0.3 11.4 0.0 2.7 3 0 0 3 3 3 0 PAS domain UPA_2 PF17809.1 KFP14993.1 - 4e-08 33.2 0.1 7.1e-08 32.4 0.1 1.4 2 0 0 2 2 2 1 UPA domain zf-CCCH PF00642.24 KFP14994.1 - 8.9e-11 41.4 24.8 0.00018 21.3 0.7 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP14994.1 - 2.5e-06 27.8 24.8 0.25 11.9 1.5 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP14994.1 - 2.8e-06 27.5 12.9 0.013 15.7 4.2 2.9 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFP14994.1 - 0.0001 22.0 1.4 0.0001 22.0 1.4 5.3 5 2 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 KFP14994.1 - 0.00036 21.2 20.5 0.26 12.0 0.2 4.6 2 2 2 4 4 4 3 Torus domain zf_CCCH_4 PF18345.1 KFP14994.1 - 0.0026 17.8 37.6 0.044 13.9 2.6 7.6 5 4 0 5 5 5 2 Zinc finger domain DUF3138 PF11336.8 KFP14994.1 - 0.18 10.4 3.2 0.26 9.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) 7tm_1 PF00001.21 KFP14995.1 - 5.2e-37 127.6 27.1 6.7e-37 127.2 27.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_9_N PF15420.6 KFP14995.1 - 0.23 11.4 4.7 0.36 10.8 4.7 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus COX2-transmemb PF09125.10 KFP14995.1 - 0.43 10.4 4.0 1.8 8.4 4.0 2.1 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Glyco_transf_24 PF18404.1 KFP14996.1 - 8.6e-148 491.0 4.5 1.9e-147 489.8 4.5 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFP14996.1 - 1.2e-69 234.5 2.9 1.5e-67 227.6 1.7 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KFP14996.1 - 2.3e-63 214.5 2.9 2.9e-59 201.1 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFP14996.1 - 3.4e-42 144.5 0.2 7.7e-42 143.3 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFP14996.1 - 4e-40 136.3 0.0 8.9e-40 135.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFP14996.1 - 3.7e-38 130.5 0.1 2.4e-37 127.9 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFP14996.1 - 4e-07 29.8 1.0 1.5e-06 28.0 1.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 PIP5K PF01504.18 KFP14997.1 - 7.6e-77 258.2 0.1 1e-76 257.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.23 KFP14998.1 - 2.8e-39 132.0 19.4 1.7e-08 34.2 0.0 9.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFP14998.1 - 7.4e-16 56.9 12.6 0.11 12.8 0.0 8.5 9 0 0 9 9 8 4 HEAT repeat HEAT_2 PF13646.6 KFP14998.1 - 2.2e-14 53.6 7.4 0.0013 19.1 0.3 5.5 2 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 KFP14998.1 - 5e-12 46.1 16.5 0.00092 19.7 0.0 6.8 5 2 2 7 7 7 4 HEAT-like repeat Cnd1 PF12717.7 KFP14998.1 - 7.4e-12 45.6 0.8 0.2 11.7 0.2 5.3 1 1 4 5 5 5 4 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 KFP14998.1 - 2.9e-08 33.7 0.0 1.3 8.7 0.0 4.3 2 1 0 4 4 4 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 KFP14998.1 - 2.9e-07 29.4 2.6 0.035 12.7 0.8 3.7 1 1 2 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 KFP14998.1 - 1.9e-06 27.6 0.1 0.023 14.3 0.0 3.7 2 1 0 3 3 3 1 CLASP N terminal CHASE6_C PF17150.4 KFP14998.1 - 3e-06 27.8 0.5 5.5 7.7 0.0 5.9 5 1 0 6 6 6 1 C-terminal domain of two-partite extracellular sensor domain Atx10homo_assoc PF09759.9 KFP14998.1 - 4.4e-05 23.4 0.2 2.3 8.3 0.0 4.9 3 2 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain RTP1_C1 PF10363.9 KFP14998.1 - 0.00041 20.5 0.2 0.035 14.3 0.3 3.2 3 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 KFP14998.1 - 0.0021 16.7 1.9 0.0055 15.3 0.4 2.3 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.16 KFP14998.1 - 0.02 15.5 10.4 0.88 10.4 0.4 5.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 KFP14998.1 - 0.024 14.8 0.2 1.1 9.4 0.1 3.3 3 1 0 4 4 4 0 V-ATPase subunit H Rcd1 PF04078.13 KFP14998.1 - 0.025 13.9 0.2 0.59 9.4 0.1 3.0 2 1 1 3 3 3 0 Cell differentiation family, Rcd1-like Tti2 PF10521.9 KFP14998.1 - 0.032 13.8 0.0 0.92 9.0 0.0 2.3 2 0 0 2 2 2 0 Tti2 family XPC-binding PF09280.11 KFP14998.1 - 0.063 13.0 0.0 49 3.8 0.0 4.1 3 0 0 3 3 3 0 XPC-binding domain DUF3731 PF12531.8 KFP14998.1 - 0.096 12.5 0.5 2.8 7.7 0.1 2.7 3 0 0 3 3 3 0 DNA-K related protein API5 PF05918.11 KFP14998.1 - 0.12 11.1 0.8 3.2 6.5 0.2 2.9 2 1 2 4 4 4 0 Apoptosis inhibitory protein 5 (API5) MMS19_C PF12460.8 KFP14998.1 - 0.34 10.0 4.6 1.2 8.2 0.4 2.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TPR_16 PF13432.6 KFP14998.1 - 0.62 10.8 8.4 3.8 8.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3361 PF11841.8 KFP14998.1 - 0.86 9.5 4.8 1.4 8.8 0.4 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3361) RAWUL PF16207.5 KFP14999.1 - 1.1e-21 77.3 0.6 2.7e-21 76.0 0.6 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP14999.1 - 0.011 15.6 2.5 0.02 14.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP14999.1 - 0.047 13.6 2.7 0.079 12.8 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP14999.1 - 0.088 13.2 2.2 0.18 12.2 2.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KFP14999.1 - 0.24 11.7 1.7 0.53 10.6 1.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP14999.1 - 0.7 9.8 4.9 1.5 8.7 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.31 KFP15001.1 - 1e-17 64.0 1.7 3e-17 62.5 1.7 1.9 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 KFP15001.1 - 4.8e-12 45.9 0.6 4.3e-07 30.0 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP15001.1 - 3.9e-06 27.0 0.1 0.012 15.8 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain HemY_N PF07219.13 KFP15001.1 - 0.048 13.8 0.2 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF4234 PF14018.6 KFP15001.1 - 0.054 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) zf-HC5HC2H_2 PF13832.6 KFP15002.1 - 1.3e-30 105.8 11.3 2.4e-30 104.9 11.3 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP15002.1 - 3.4e-20 72.1 10.6 3.4e-20 72.1 10.6 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP15002.1 - 0.00098 18.6 1.1 0.00098 18.6 1.1 2.7 3 0 0 3 3 3 1 PHD-finger DUF2180 PF09947.9 KFP15002.1 - 1.8 8.6 8.1 3.4 7.7 4.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) EPOP PF15223.6 KFP15003.1 - 2.5e-119 399.4 7.8 3.5e-119 398.9 7.8 1.1 1 0 0 1 1 1 1 Elongin BC and Polycomb repressive complex 2-associated protein Ski_Sno PF02437.17 KFP15003.1 - 4.9e-15 55.2 0.1 1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family Nebulin PF00880.18 KFP15005.1 - 3.5e-32 109.8 1.8 1.4e-12 47.3 0.1 3.3 3 0 0 3 3 3 3 Nebulin repeat SH3_9 PF14604.6 KFP15005.1 - 2.4e-16 59.3 0.1 3.9e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP15005.1 - 3.6e-13 48.9 0.0 7.5e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP15005.1 - 2.1e-05 24.1 0.0 4.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PSI PF01437.25 KFP15006.1 - 8.9e-08 32.6 10.9 1.5e-07 31.8 10.9 1.4 1 0 0 1 1 1 1 Plexin repeat MGC-24 PF05283.11 KFP15006.1 - 0.002 18.6 8.0 0.0059 17.1 8.0 1.7 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KFP15006.1 - 0.097 12.1 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2157 PF09925.9 KFP15006.1 - 0.21 11.4 0.9 0.34 10.7 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PSI_integrin PF17205.3 KFP15006.1 - 1.8 8.3 9.1 3.2 7.6 9.1 1.4 1 0 0 1 1 1 0 Integrin plexin domain PetM PF08041.11 KFP15007.1 - 0.026 14.1 1.5 0.04 13.5 1.5 1.3 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 MAM PF00629.23 KFP15008.1 - 1.2e-23 83.8 1.3 1.3e-23 83.7 1.3 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFP15009.1 - 3.4e-39 134.4 0.0 3.8e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KFP15010.1 - 7.6e-19 68.2 0.6 8.4e-19 68.0 0.6 1.0 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu HIGH_NTase1 PF05636.11 KFP15010.1 - 0.06 12.5 0.0 0.07 12.3 0.0 1.0 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase RRM_1 PF00076.22 KFP15011.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP15011.1 - 0.028 14.3 0.0 0.34 10.8 0.1 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP15011.1 - 0.59 10.2 0.0 0.59 10.2 0.0 4.0 5 1 0 5 5 5 0 RNA binding motif HH_signal PF01085.18 KFP15012.1 - 2.8e-87 290.4 0.0 3.3e-87 290.2 0.0 1.1 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Hint PF01079.20 KFP15012.1 - 7.2e-14 51.8 0.1 9.8e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Hint module Peptidase_M15_3 PF08291.11 KFP15012.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M15 Ribosomal_S6e PF01092.19 KFP15012.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S6e Laminin_EGF PF00053.24 KFP15014.1 - 1.9e-11 43.9 14.6 1.9e-11 43.9 14.6 2.8 3 0 0 3 3 3 1 Laminin EGF domain EGF_2 PF07974.13 KFP15014.1 - 0.01 16.2 6.6 0.01 16.2 6.6 3.6 4 1 1 5 5 5 0 EGF-like domain SNARE PF05739.19 KFP15015.1 - 0.0099 15.9 0.2 0.03 14.3 0.2 1.9 1 0 0 1 1 1 1 SNARE domain HD_assoc PF13286.6 KFP15015.1 - 0.026 15.0 0.4 0.65 10.6 0.1 2.5 2 1 0 2 2 2 0 Phosphohydrolase-associated domain Telomere_reg-2 PF10193.9 KFP15015.1 - 0.079 13.4 3.8 2 8.9 0.4 2.2 2 0 0 2 2 2 0 Telomere length regulation protein ApoLp-III PF07464.11 KFP15015.1 - 0.22 11.6 9.0 0.22 11.6 0.3 2.6 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.6 KFP15015.1 - 0.38 10.1 5.7 0.65 9.3 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 KFP15015.1 - 0.54 9.0 5.6 0.16 10.7 1.9 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter FUSC-like PF12805.7 KFP15015.1 - 5.4 6.0 7.0 1.3 8.1 2.1 2.1 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS LMBR1 PF04791.16 KFP15015.1 - 6.8 5.5 7.3 0.59 9.0 1.5 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF745 PF05335.13 KFP15015.1 - 6.8 6.4 9.0 9.4 5.9 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TLD PF07534.16 KFP15016.1 - 1.7e-27 96.3 0.0 1.9e-14 54.1 0.0 2.5 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.18 KFP15016.1 - 5.9e-24 84.9 0.7 1.1e-23 84.1 0.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KFP15017.1 - 1.6e-33 114.2 24.5 9.1e-05 23.2 0.2 11.6 12 0 0 12 12 12 8 WD domain, G-beta repeat WD40_like PF17005.5 KFP15017.1 - 3e-08 33.4 6.8 0.049 13.0 0.1 4.6 4 1 1 5 5 5 3 WD40-like domain ANAPC4_WD40 PF12894.7 KFP15017.1 - 5.8e-08 32.9 1.2 1 9.7 0.0 6.5 2 2 5 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP15017.1 - 0.071 11.8 1.8 37 2.9 0.1 4.5 3 2 2 5 5 5 0 Nup133 N terminal like PQQ_3 PF13570.6 KFP15017.1 - 0.19 12.3 11.5 7.8 7.1 0.2 5.9 5 1 2 7 7 7 0 PQQ-like domain BAR PF03114.18 KFP15018.1 - 1.6e-57 194.9 6.0 1.6e-57 194.9 6.0 1.6 2 0 0 2 2 2 1 BAR domain RhoGAP PF00620.27 KFP15018.1 - 6.3e-46 156.0 0.1 4e-45 153.3 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain DUF773 PF05600.12 KFP15018.1 - 0.029 13.1 0.6 0.048 12.4 0.6 1.3 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF846 PF05832.12 KFP15019.1 - 4.4e-54 182.3 9.8 5.2e-54 182.1 9.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.6 KFP15019.1 - 0.15 11.1 1.9 0.3 10.2 1.9 1.4 1 0 0 1 1 1 0 TMEM192 family Tektin PF03148.14 KFP15020.1 - 2e-154 514.0 32.6 2.3e-154 513.8 32.6 1.0 1 0 0 1 1 1 1 Tektin family Dna2 PF08696.11 KFP15020.1 - 0.023 14.5 0.8 0.023 14.5 0.8 2.5 2 2 1 3 3 3 0 DNA replication factor Dna2 PKHD_C PF18331.1 KFP15020.1 - 0.028 14.5 0.4 0.32 11.1 0.1 2.9 3 0 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain Baculo_PEP_C PF04513.12 KFP15020.1 - 0.44 10.6 8.1 1.8 8.6 2.9 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sulfotransfer_1 PF00685.27 KFP15022.1 - 3.8e-32 111.8 0.0 4.5e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP15022.1 - 2.5e-11 44.4 0.0 3.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP15022.1 - 0.0079 16.1 0.0 0.072 13.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family UbiA PF01040.18 KFP15023.1 - 4.1e-55 186.8 13.6 6e-55 186.3 13.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Sulfotransfer_1 PF00685.27 KFP15024.1 - 1.7e-31 109.7 0.0 2e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP15024.1 - 1.5e-10 41.9 0.0 2.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP15024.1 - 0.0079 16.1 0.0 0.072 13.0 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family NTR PF01759.21 KFP15025.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.17 KFP15025.1 - 0.073 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase Glycos_transf_2 PF00535.26 KFP15026.1 - 5.8e-21 75.0 0.0 9.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFP15026.1 - 1e-06 28.8 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFP15026.1 - 6.3e-05 23.4 0.0 0.00083 19.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KFP15026.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 TFCD_C PF12612.8 KFP15027.1 - 9.4e-70 234.3 0.4 2.4e-68 229.7 0.0 3.1 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 KFP15027.1 - 5.2e-08 33.2 2.3 0.17 12.4 0.0 6.3 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 KFP15027.1 - 0.00044 20.3 7.9 0.4 11.1 0.0 7.6 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 KFP15027.1 - 0.0055 17.1 0.6 3.6 8.1 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 KFP15027.1 - 0.0067 16.5 0.2 3.3 7.7 0.0 4.7 7 0 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 STAG PF08514.11 KFP15027.1 - 0.037 13.9 0.8 4.8 7.1 0.0 3.1 2 0 0 2 2 2 0 STAG domain HEAT_PBS PF03130.16 KFP15027.1 - 0.33 11.7 2.9 33 5.6 0.0 5.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat zf-C2H2_7 PF15269.6 KFP15028.1 - 1.8e-36 123.9 11.3 5.9e-36 122.3 11.3 1.9 1 0 0 1 1 1 1 Zinc-finger zf-H2C2_5 PF13909.6 KFP15028.1 - 0.15 11.9 5.5 0.34 10.7 5.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP15028.1 - 1.8 9.2 13.3 1.2 9.7 5.9 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fructosamin_kin PF03881.14 KFP15029.1 - 8.5e-74 248.3 0.0 2e-73 247.1 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFP15029.1 - 2.3e-12 47.4 0.0 3.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP15029.1 - 0.0011 18.6 0.0 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KFP15029.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 KFP15030.1 - 2.6e-69 233.6 0.5 1.1e-68 231.6 0.5 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFP15030.1 - 9.3e-08 32.3 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4763 PF15960.5 KFP15030.1 - 0.06 12.6 0.1 0.093 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Ras PF00071.22 KFP15031.1 - 1e-35 122.7 0.0 1.6e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15031.1 - 1.4e-14 54.3 0.0 2.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SOCS_box PF07525.16 KFP15031.1 - 6.6e-07 29.6 1.5 1.4e-06 28.5 1.5 1.6 1 0 0 1 1 1 1 SOCS box Arf PF00025.21 KFP15031.1 - 0.00066 19.2 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family ANAPC4_WD40 PF12894.7 KFP15032.1 - 7.4e-06 26.2 0.0 0.031 14.6 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KFP15032.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) PHTB1_N PF14727.6 KFP15032.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 PTHB1 N-terminus DUF3761 PF12587.8 KFP15032.1 - 0.17 12.3 0.1 0.43 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) WD40 PF00400.32 KFP15032.1 - 0.3 12.0 8.0 0.74 10.8 0.2 4.0 3 2 2 5 5 5 0 WD domain, G-beta repeat Forkhead PF00250.18 KFP15033.1 - 4.8e-41 138.9 0.2 8.1e-41 138.2 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain Fe_hyd_lg_C PF02906.14 KFP15035.1 - 5.7e-70 235.7 0.0 9.2e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KFP15035.1 - 1.9e-08 34.3 0.8 2.8e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 Iron hydrogenase small subunit DUF4564 PF15169.6 KFP15036.1 - 2.6e-84 281.6 0.0 3e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) Glyco_hydro_20 PF00728.22 KFP15037.1 - 4.9e-08 32.8 0.4 1.2e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain DUF3546 PF12066.8 KFP15037.1 - 0.14 12.3 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) 7tm_1 PF00001.21 KFP15038.1 - 3.2e-21 75.8 4.8 3.7e-21 75.6 4.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP15038.1 - 0.00038 19.8 1.6 0.00052 19.4 1.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw O-ag_pol_Wzy PF14296.6 KFP15038.1 - 0.0059 15.3 4.1 0.0097 14.6 3.5 1.6 1 1 1 2 2 2 1 O-antigen polysaccharide polymerase Wzy Anticodon_1 PF08264.13 KFP15038.1 - 0.021 14.8 0.4 0.048 13.6 0.2 1.7 1 1 1 2 2 2 0 Anticodon-binding domain of tRNA DUF443 PF04276.12 KFP15038.1 - 0.025 14.4 0.8 0.04 13.7 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF443) DUF1129 PF06570.11 KFP15038.1 - 0.1 12.1 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2975 PF11188.8 KFP15038.1 - 9.5 6.1 7.1 28 4.6 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) 7tm_1 PF00001.21 KFP15039.1 - 2.1e-46 158.4 24.2 2.8e-46 158.0 24.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP15039.1 - 0.0017 17.7 23.1 0.0051 16.1 1.7 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Man-6-P_recep PF02157.15 KFP15039.1 - 0.12 11.4 0.2 0.25 10.4 0.2 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor V-set PF07686.17 KFP15040.1 - 0.0047 17.1 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain RTA1 PF04479.13 KFP15040.1 - 0.045 13.4 0.0 0.05 13.2 0.0 1.0 1 0 0 1 1 1 0 RTA1 like protein MFS_2 PF13347.6 KFP15040.1 - 0.047 12.3 0.1 0.052 12.1 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Insulin_TMD PF17870.1 KFP15040.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Septin PF00735.18 KFP15041.1 - 7.4e-102 340.4 0.9 8.4e-102 340.2 0.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP15041.1 - 3.2e-10 40.1 0.1 7.1e-10 39.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP15041.1 - 3.4e-07 30.3 1.4 3.2e-06 27.1 0.6 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP15041.1 - 8.3e-06 25.5 1.2 0.00011 21.8 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP15041.1 - 1.1e-05 24.9 0.1 1.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KFP15041.1 - 2.3e-05 24.5 2.1 0.0058 16.7 0.7 2.3 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 KFP15041.1 - 4.5e-05 23.7 0.0 9.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP15041.1 - 8.6e-05 22.2 0.2 0.00033 20.3 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KFP15041.1 - 0.00064 20.1 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KFP15041.1 - 0.0014 17.8 1.4 0.0026 17.0 1.3 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_24 PF13479.6 KFP15041.1 - 0.0016 18.2 0.1 0.0084 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP15041.1 - 0.0017 18.6 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IIGP PF05049.13 KFP15041.1 - 0.0019 17.3 1.0 0.019 14.0 0.0 2.3 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 KFP15041.1 - 0.0029 18.1 1.8 0.005 17.4 1.8 1.7 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KFP15041.1 - 0.0065 15.7 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Gtr1_RagA PF04670.12 KFP15041.1 - 0.01 15.2 0.2 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KFP15041.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KFP15041.1 - 0.011 15.5 1.4 0.018 14.8 1.4 1.2 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KFP15041.1 - 0.012 15.4 0.3 0.16 11.7 0.1 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KFP15041.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFP15041.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP15041.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arf PF00025.21 KFP15041.1 - 0.033 13.7 0.1 0.065 12.7 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 KFP15041.1 - 0.041 13.9 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP15041.1 - 0.046 13.3 0.2 0.13 11.8 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 KFP15041.1 - 0.051 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 KFP15041.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.6 KFP15041.1 - 0.081 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFP15041.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 KFP15041.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KFP15041.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CBM_10 PF02013.16 KFP15042.1 - 3.6 8.1 8.0 5.6 7.5 8.0 1.2 1 0 0 1 1 1 0 Cellulose or protein binding domain TNRC6-PABC_bdg PF16608.5 KFP15043.1 - 3.2e-105 352.0 36.8 2.6e-75 253.8 7.7 8.1 5 3 1 7 7 7 2 TNRC6-PABC binding domain M_domain PF12938.7 KFP15043.1 - 5.7e-67 226.1 42.3 5.7e-67 226.1 42.3 6.6 4 1 3 7 7 7 1 M domain of GW182 Ago_hook PF10427.9 KFP15043.1 - 8.4e-17 62.2 41.7 8.4e-17 62.2 41.7 11.0 3 2 5 9 9 9 1 Argonaute hook UBA PF00627.31 KFP15043.1 - 4.7e-06 26.4 0.1 9.3e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 KFP15043.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP15043.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2748 PF10871.8 KFP15043.1 - 0.51 8.9 4.6 1.5 7.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) THOC7 PF05615.13 KFP15043.1 - 3.1 8.1 8.2 5.9 7.2 8.2 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Ras PF00071.22 KFP15044.1 - 1.5e-29 102.7 0.0 1.8e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15044.1 - 3.5e-16 59.5 0.0 4.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP15044.1 - 9.9e-08 31.6 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP15044.1 - 1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP15044.1 - 3.4e-05 23.9 0.0 4.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP15044.1 - 0.00072 19.5 0.1 0.068 13.1 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP15044.1 - 0.00086 18.9 0.0 0.042 13.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KFP15044.1 - 0.0051 17.1 0.1 0.024 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP15044.1 - 0.0084 16.5 0.1 0.015 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KFP15044.1 - 0.013 15.4 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFP15044.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFP15044.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 KFP15044.1 - 0.035 13.3 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Viral_helicase1 PF01443.18 KFP15044.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PRELI PF04707.14 KFP15045.1 - 2.2e-51 173.8 0.2 3.3e-51 173.2 0.2 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.20 KFP15045.1 - 5e-41 140.1 0.0 8.5e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP15045.1 - 7.8e-06 26.0 0.1 2e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AAA_15 PF13175.6 KFP15045.1 - 0.11 12.2 0.5 0.14 11.8 0.5 1.1 1 0 0 1 1 1 0 AAA ATPase domain Glyco_transf_18 PF15024.6 KFP15048.1 - 1.3e-255 849.3 0.0 1.6e-255 849.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 UNC-93 PF05978.16 KFP15049.1 - 7.4e-52 175.2 14.8 7.4e-52 175.2 14.8 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFP15049.1 - 7e-10 38.3 43.3 1.6e-07 30.6 28.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OCIA PF07051.11 KFP15049.1 - 0.082 12.9 0.7 1.3 9.1 0.0 2.8 2 1 1 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) OAD_gamma PF04277.13 KFP15049.1 - 0.1 13.2 0.2 0.1 13.2 0.2 2.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain RRM_1 PF00076.22 KFP15050.1 - 5.8e-21 74.1 0.0 9.9e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP15050.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFP15050.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 KFP15050.1 - 5.8 6.7 23.6 7.3 6.4 23.6 1.2 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 KFP15050.1 - 6.6 6.4 14.9 7.7 6.1 14.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Methyltransf_16 PF10294.9 KFP15051.1 - 1.5e-12 47.6 0.0 2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase JmjC PF02373.22 KFP15052.1 - 8e-30 103.6 0.0 1.6e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KFP15052.1 - 2e-18 67.0 0.1 4.4e-18 65.9 0.1 1.5 1 1 0 1 1 1 1 Cupin-like domain SR-25 PF10500.9 KFP15052.1 - 0.016 14.8 12.1 0.03 13.9 12.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 KFP15052.1 - 0.13 10.4 14.2 0.17 9.9 14.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_transf_29 PF00777.18 KFP15053.1 - 3.1e-69 233.4 0.0 3.7e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Globin PF00042.22 KFP15054.1 - 3e-24 85.7 0.1 4.4e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 Globin DUF592 PF04574.13 KFP15054.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Acetyltransf_1 PF00583.25 KFP15055.1 - 6.3e-14 52.2 0.0 7.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP15055.1 - 6.6e-08 32.5 0.0 9.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP15055.1 - 3.1e-06 27.5 0.0 4.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP15055.1 - 0.064 13.3 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2811 PF10929.8 KFP15055.1 - 0.15 12.4 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) MobA_MobL PF03389.15 KFP15055.1 - 0.23 11.1 0.1 0.32 10.7 0.1 1.1 1 0 0 1 1 1 0 MobA/MobL family UQ_con PF00179.26 KFP15057.1 - 1.9e-23 82.7 0.0 5.1e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Pribosyl_synth PF14572.6 KFP15058.1 - 3.6e-101 336.8 0.8 3.6e-101 336.8 0.8 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP15058.1 - 1.6e-38 131.2 0.2 3.4e-38 130.2 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP15058.1 - 1.7e-06 27.6 0.1 4.5e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Spc7 PF08317.11 KFP15059.1 - 8.8e-06 24.8 21.3 0.00099 18.1 8.3 2.7 2 1 0 3 3 3 2 Spc7 kinetochore protein DUF4795 PF16043.5 KFP15059.1 - 5.4e-05 22.9 22.6 0.00046 19.8 0.9 3.7 2 2 1 3 3 3 2 Domain of unknown function (DUF4795) DUF948 PF06103.11 KFP15059.1 - 0.00028 21.1 11.9 0.0093 16.2 1.8 3.4 3 1 0 3 3 3 2 Bacterial protein of unknown function (DUF948) Cas_DxTHG PF09455.10 KFP15059.1 - 0.00089 18.9 0.3 0.0011 18.7 0.3 1.1 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family SesA PF17107.5 KFP15059.1 - 0.0019 18.4 12.1 0.0021 18.3 4.4 3.2 2 2 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CorA PF01544.18 KFP15059.1 - 0.0034 16.8 3.6 0.0034 16.8 3.6 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4355 PF14265.6 KFP15059.1 - 0.019 15.2 6.1 0.05 13.8 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) adh_short PF00106.25 KFP15059.1 - 0.035 13.6 1.6 0.056 12.9 0.4 1.9 2 1 0 2 2 2 0 short chain dehydrogenase PCRF PF03462.18 KFP15059.1 - 0.041 13.8 15.3 1 9.2 0.2 3.0 2 1 1 3 3 3 0 PCRF domain T4_baseplate PF12322.8 KFP15059.1 - 0.043 13.3 0.2 0.061 12.8 0.2 1.3 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Lipoprotein_6 PF01441.19 KFP15059.1 - 0.044 13.8 1.1 0.098 12.7 0.2 2.0 2 0 0 2 2 2 0 Lipoprotein TetR_C_11 PF16859.5 KFP15059.1 - 0.049 13.9 4.5 0.51 10.7 0.0 3.2 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain MerR-DNA-bind PF09278.11 KFP15059.1 - 0.054 14.0 4.3 0.054 14.0 4.3 3.6 3 1 1 4 4 3 0 MerR, DNA binding DUF3496 PF12001.8 KFP15059.1 - 0.1 13.0 4.8 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Myb_DNA-bind_4 PF13837.6 KFP15059.1 - 0.11 12.9 0.5 0.27 11.6 0.3 1.8 2 0 0 2 2 1 0 Myb/SANT-like DNA-binding domain PET10 PF17316.2 KFP15059.1 - 0.13 11.8 0.4 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Petite colonies protein 10 DUF445 PF04286.12 KFP15059.1 - 0.21 11.4 4.4 0.32 10.8 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Remorin_C PF03763.13 KFP15059.1 - 0.24 11.3 5.0 0.31 10.9 2.6 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region Spore_III_AB PF09548.10 KFP15059.1 - 0.3 11.2 13.8 0.34 11.0 0.9 2.5 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2383 PF09537.10 KFP15059.1 - 0.3 11.4 10.3 9 6.7 1.6 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF2383) DUF4363 PF14276.6 KFP15059.1 - 0.41 10.8 3.9 3.7 7.7 0.3 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4363) Muted PF14942.6 KFP15059.1 - 0.71 10.2 14.4 0.26 11.6 5.4 3.0 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Syntaxin-6_N PF09177.11 KFP15059.1 - 0.72 10.4 14.5 12 6.5 0.2 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal BshC PF10079.9 KFP15059.1 - 0.79 8.4 13.1 0.21 10.3 6.9 2.5 2 1 1 3 3 3 0 Bacillithiol biosynthesis BshC Occludin_ELL PF07303.13 KFP15059.1 - 0.81 10.4 10.5 16 6.3 1.5 3.7 3 1 0 3 3 3 0 Occludin homology domain FUSC PF04632.12 KFP15059.1 - 0.88 8.0 12.9 0.1 11.1 6.2 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Peptidase_C98 PF15499.6 KFP15059.1 - 0.88 9.0 5.3 3 7.3 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Interferon PF00143.19 KFP15059.1 - 0.93 9.7 10.9 0.18 11.9 2.5 2.9 2 1 1 3 3 3 0 Interferon alpha/beta domain zf-CpG_bind_C PF12269.8 KFP15059.1 - 1.1 9.0 8.4 0.15 11.8 3.6 1.9 2 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF148 PF02520.17 KFP15059.1 - 1.8 8.7 13.0 4.1 7.6 2.2 3.3 3 2 0 3 3 3 0 Domain of unknown function DUF148 YlbD_coat PF14071.6 KFP15059.1 - 2.1 8.6 11.6 2 8.7 0.3 3.1 3 1 0 3 3 3 0 Putative coat protein FAP206 PF12018.8 KFP15059.1 - 2.2 7.7 9.7 5.1 6.5 5.2 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF4407 PF14362.6 KFP15059.1 - 2.4 7.4 12.4 1.5 8.1 9.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 KFP15059.1 - 2.4 8.7 24.5 17 6.0 9.3 4.5 2 1 1 4 4 4 0 Spectrin repeat BLOC1_2 PF10046.9 KFP15059.1 - 2.5 8.4 16.5 3.8 7.9 2.6 4.5 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA2 PF16740.5 KFP15059.1 - 3.5 7.5 20.5 3.1 7.6 4.4 4.3 3 2 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Golgin_A5 PF09787.9 KFP15059.1 - 3.8 6.9 18.9 1.3 8.4 11.7 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Wbp11 PF09429.10 KFP15059.1 - 7.6 7.0 17.9 0.69 10.3 5.7 3.9 2 2 2 4 4 4 0 WW domain binding protein 11 Forkhead PF00250.18 KFP15061.1 - 1.3e-36 124.7 0.1 2.4e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Exo70 PF03081.15 KFP15062.1 - 4e-82 276.3 0.7 4e-82 276.3 0.7 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 KFP15062.1 - 0.0044 16.9 5.0 0.015 15.2 4.4 2.3 2 0 0 2 2 2 1 Sec34-like family Vps52 PF04129.12 KFP15062.1 - 0.024 13.4 8.3 0.081 11.6 3.0 2.3 2 0 0 2 2 2 0 Vps52 / Sac2 family APG17 PF04108.12 KFP15062.1 - 0.047 12.8 4.6 0.17 11.0 4.6 2.0 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4404 PF14357.6 KFP15062.1 - 0.068 13.8 2.0 0.97 10.1 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) MTD PF01993.18 KFP15062.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Sep15_SelM PF08806.11 KFP15062.1 - 0.11 12.6 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 Sep15/SelM redox domain Atg14 PF10186.9 KFP15062.1 - 0.62 9.1 8.0 2.6 7.1 2.9 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GIT1_C PF12205.8 KFP15062.1 - 1.1 9.4 3.9 7.3 6.7 0.0 3.3 2 1 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term COG5 PF10392.9 KFP15062.1 - 1.8 8.7 13.2 0.021 15.0 4.2 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Exonuc_VII_L PF02601.15 KFP15062.1 - 4.9 6.6 7.0 0.95 9.0 2.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Sec20 PF03908.13 KFP15062.1 - 5.4 7.0 6.7 1.1 9.2 1.3 2.8 4 0 0 4 4 4 0 Sec20 SRP68 PF16969.5 KFP15063.1 - 1.2e-154 516.4 12.3 1.3e-154 516.3 12.3 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_6 PF13174.6 KFP15063.1 - 0.0015 19.0 2.4 1.7 9.4 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP15063.1 - 0.0082 15.9 3.3 1.1 9.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat RuvC_III PF18541.1 KFP15063.1 - 0.047 13.6 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 TPR_2 PF07719.17 KFP15063.1 - 0.061 13.5 11.4 0.42 10.9 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5340 PF17275.2 KFP15063.1 - 0.35 11.0 6.7 0.77 9.9 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5340) TPR_12 PF13424.6 KFP15063.1 - 5.2 7.4 8.4 14 6.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Plectin PF00681.20 KFP15064.1 - 1.8e-49 165.3 1.0 7.5e-13 48.1 0.1 7.7 5 1 2 7 7 7 5 Plectin repeat SH3_10 PF17902.1 KFP15064.1 - 2.5e-21 75.5 0.1 8.6e-21 73.8 0.1 2.0 1 0 0 1 1 1 1 SH3 domain Spectrin PF00435.21 KFP15064.1 - 1.2e-05 25.7 7.7 3.5e-05 24.2 3.4 14.3 8 1 2 14 14 14 3 Spectrin repeat Phage_XkdX PF09693.10 KFP15064.1 - 0.019 15.0 0.2 19 5.4 0.0 3.5 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) ADH_N_2 PF16884.5 KFP15064.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase RepA_C PF04796.12 KFP15064.1 - 1.2 9.2 5.6 20 5.2 1.1 3.2 2 0 0 2 2 2 0 Plasmid encoded RepA protein Pkinase PF00069.25 KFP15065.1 - 4.5e-80 268.8 0.0 5.2e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15065.1 - 9.4e-38 130.0 0.0 1.2e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP15065.1 - 3.2e-05 23.0 0.0 0.0016 17.5 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP15065.1 - 0.00014 21.3 0.6 0.031 13.6 0.1 2.3 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 KFP15065.1 - 0.0061 16.5 0.1 0.047 13.6 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP15065.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP15065.1 - 0.048 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2322 PF10084.9 KFP15065.1 - 0.063 13.3 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Ten1_2 PF15490.6 KFP15066.1 - 2.3e-44 149.9 0.0 2.5e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit ACOX PF01756.19 KFP15067.1 - 4.7e-69 231.6 1.2 1.2e-68 230.3 1.1 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFP15067.1 - 9.2e-27 94.1 0.9 4.2e-26 92.0 0.1 2.4 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFP15067.1 - 6.7e-12 45.5 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DGF-1_C PF11040.8 KFP15068.1 - 2 8.5 9.3 14 5.8 0.5 4.0 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PBP PF01161.20 KFP15069.1 - 7.7e-11 42.4 0.1 1.3e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-C3HC4_4 PF15227.6 KFP15070.1 - 3.5e-12 46.3 3.9 4.8e-12 45.8 3.9 1.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFP15070.1 - 4.1e-12 45.9 6.4 5e-12 45.6 6.4 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP15070.1 - 7.7e-10 38.5 5.0 8.6e-10 38.3 5.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP15070.1 - 5.9e-09 35.6 4.7 6.8e-09 35.4 4.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP15070.1 - 2.4e-07 30.5 3.8 2.4e-07 30.5 3.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP15070.1 - 6.5e-07 29.6 5.9 7.4e-07 29.4 5.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 KFP15070.1 - 7.2e-07 29.0 2.2 8.2e-07 28.8 2.2 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KFP15070.1 - 9.9e-07 28.6 5.4 1.2e-06 28.4 5.4 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFP15070.1 - 0.00016 21.3 3.9 0.0005 19.8 3.9 1.8 1 1 0 1 1 1 1 RING-like zinc finger U-box PF04564.15 KFP15070.1 - 0.00017 21.7 0.0 0.0002 21.5 0.0 1.1 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 KFP15070.1 - 0.00079 19.2 5.6 0.001 18.9 5.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFP15070.1 - 0.0053 16.9 4.1 0.0062 16.6 4.1 1.1 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFP15070.1 - 0.58 10.5 8.4 2.8 8.3 8.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain SPRY PF00622.28 KFP15071.1 - 2.2e-05 24.6 0.5 4.8e-05 23.5 0.5 1.6 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP15071.1 - 0.0015 18.2 0.0 0.004 16.7 0.0 1.8 1 0 0 1 1 1 1 SPRY-associated domain TBCC_N PF16752.5 KFP15071.1 - 0.032 14.7 2.4 0.36 11.3 0.1 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain GRAM PF02893.20 KFP15072.1 - 2e-15 56.6 0.0 2.7e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KFP15072.1 - 0.067 13.4 0.0 0.098 12.9 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KFP15072.1 - 0.18 12.2 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain C2 PF00168.30 KFP15073.1 - 4.9e-30 103.9 0.0 4.3e-15 55.9 0.0 4.1 2 1 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.9 KFP15073.1 - 4.3e-14 52.9 15.2 9.7e-09 35.6 0.3 3.6 2 2 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF4795 PF16043.5 KFP15073.1 - 0.011 15.4 9.2 0.024 14.3 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) zf_CCCH_5 PF18384.1 KFP15074.1 - 7.1e-21 74.0 13.3 7.1e-21 74.0 13.3 3.9 3 1 0 3 3 3 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 KFP15074.1 - 7.3e-06 25.8 6.1 4.2e-05 23.3 1.0 7.1 8 1 0 8 8 7 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFP15074.1 - 0.00011 22.0 10.6 0.00011 22.0 10.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.8 KFP15074.1 - 0.0003 20.2 5.4 0.00047 19.5 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) zf_CCCH_4 PF18345.1 KFP15074.1 - 0.00043 20.2 0.5 0.039 14.0 0.0 6.3 6 1 0 6 6 6 2 Zinc finger domain Laminin_II PF06009.12 KFP15074.1 - 0.0054 16.8 1.2 0.01 15.9 1.2 1.4 1 0 0 1 1 1 1 Laminin Domain II THOC7 PF05615.13 KFP15074.1 - 0.009 16.3 0.6 0.009 16.3 0.6 1.6 2 0 0 2 2 1 1 Tho complex subunit 7 Fez1 PF06818.15 KFP15074.1 - 0.0091 16.5 8.8 0.02 15.4 8.8 1.5 1 0 0 1 1 1 1 Fez1 Sds3 PF08598.11 KFP15074.1 - 0.076 13.0 1.9 0.16 12.0 1.9 1.5 1 0 0 1 1 1 0 Sds3-like DUF2205 PF10224.9 KFP15074.1 - 0.39 10.7 4.7 0.18 11.8 1.4 2.2 2 0 0 2 2 2 0 Short coiled-coil protein DUF3560 PF12083.8 KFP15074.1 - 0.64 10.2 5.1 1.1 9.5 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) RRP36 PF06102.12 KFP15074.1 - 0.84 9.6 7.6 0.78 9.7 4.3 2.3 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 Alanine_zipper PF11839.8 KFP15074.1 - 1.4 9.3 7.9 2.7 8.4 7.9 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Ribosomal_S27e PF01667.17 KFP15074.1 - 1.6 8.5 7.3 4.2 7.2 7.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 DUF3584 PF12128.8 KFP15074.1 - 4.4 4.7 12.6 6.1 4.2 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Histone PF00125.24 KFP15075.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP15075.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFP15075.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFP15075.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP15075.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1681 PF07933.14 KFP15076.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) GHMP_kinases_C PF08544.13 KFP15078.1 - 5.2e-15 55.6 0.1 1.3e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFP15078.1 - 3.7e-14 52.7 0.2 1.1e-13 51.2 0.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Integrin_beta PF00362.18 KFP15079.1 - 8.9e-103 343.3 0.0 1.5e-102 342.5 0.0 1.4 1 0 0 1 1 1 1 Integrin beta chain VWA domain fn3 PF00041.21 KFP15079.1 - 1.2e-65 217.9 2.2 2.3e-17 63.1 0.2 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Calx-beta PF03160.14 KFP15079.1 - 1.8e-16 60.1 0.5 4.4e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Calx-beta domain Integrin_B_tail PF07965.12 KFP15079.1 - 4.6e-16 59.1 8.5 4.6e-16 59.1 8.5 2.5 2 0 0 2 2 2 1 Integrin beta tail domain PSI_integrin PF17205.3 KFP15079.1 - 2e-10 40.3 8.0 2e-10 40.3 8.0 3.8 3 0 0 3 3 3 1 Integrin plexin domain I-EGF_1 PF18372.1 KFP15079.1 - 9.5e-10 38.4 4.7 9.5e-10 38.4 4.7 5.5 5 0 0 5 5 5 2 Integrin beta epidermal growth factor like domain 1 Pur_ac_phosph_N PF16656.5 KFP15079.1 - 1.3e-09 38.4 0.0 0.047 14.3 0.0 5.4 4 2 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain EGF_2 PF07974.13 KFP15079.1 - 3e-05 24.3 87.4 0.0011 19.3 11.3 5.6 5 1 0 5 5 5 4 EGF-like domain SEA PF01390.20 KFP15079.1 - 0.00029 20.9 0.0 0.00074 19.6 0.0 1.7 1 0 0 1 1 1 1 SEA domain EGF_Tenascin PF18720.1 KFP15079.1 - 1.2 9.3 45.8 0.5 10.5 2.3 5.0 4 0 0 4 4 4 0 Tenascin EGF domain HCNGP PF07818.13 KFP15080.1 - 1.1e-34 118.9 0.3 1.9e-34 118.2 0.3 1.4 1 0 0 1 1 1 1 HCNGP-like protein Trp_DMAT PF11991.8 KFP15080.1 - 0.029 13.8 0.1 0.041 13.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase RecQ5 PF06959.11 KFP15081.1 - 1e-27 97.5 14.3 2.3e-27 96.3 14.3 1.6 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) DEAD PF00270.29 KFP15081.1 - 3.5e-20 72.5 0.1 7.9e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP15081.1 - 4.9e-16 59.1 0.0 4.2e-12 46.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFP15081.1 - 4.3e-10 40.2 2.3 1.6e-09 38.4 2.3 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFP15081.1 - 0.00012 22.2 0.0 0.00035 20.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SRI PF08236.11 KFP15081.1 - 0.002 18.3 2.3 0.0031 17.6 0.3 2.3 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain TFIIS_M PF07500.14 KFP15081.1 - 0.0057 17.1 0.0 0.025 15.0 0.0 2.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PAT1 PF09770.9 KFP15081.1 - 0.2 9.9 9.8 0.28 9.4 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4713 PF15831.5 KFP15082.1 - 1.5e-23 83.0 12.6 1.7e-23 82.8 12.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) DUF3593 PF12159.8 KFP15082.1 - 0.00089 19.3 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Shisa PF13908.6 KFP15082.1 - 0.0025 18.1 2.2 0.0025 18.1 2.2 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Corona_S2 PF01601.16 KFP15082.1 - 0.02 13.4 4.0 0.02 13.4 4.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.11 KFP15082.1 - 0.41 8.5 6.7 0.4 8.6 6.7 1.1 1 0 0 1 1 1 0 Prominin FAM163 PF15069.6 KFP15082.1 - 1.7 9.1 8.0 2.2 8.7 8.0 1.2 1 0 0 1 1 1 0 FAM163 family MyTH4 PF00784.17 KFP15083.1 - 1.1e-30 106.3 0.4 5e-30 104.2 0.1 2.2 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.18 KFP15083.1 - 7.4e-11 42.5 0.4 7.4e-11 42.5 0.4 2.1 2 0 0 2 2 2 1 FERM central domain FERM_f0 PF16511.5 KFP15083.1 - 0.023 15.0 0.9 0.074 13.4 0.0 2.2 3 0 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM SH3_2 PF07653.17 KFP15084.1 - 6e-11 41.9 0.0 1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP15084.1 - 3.8e-07 29.9 0.0 6.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP15084.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Myosin_head PF00063.21 KFP15085.1 - 1.1e-193 645.2 0.0 1.4e-193 644.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 KFP15085.1 - 8.4e-22 77.7 0.0 3.2e-21 75.9 0.0 2.1 1 0 0 1 1 1 1 MyTH4 domain IQ PF00612.27 KFP15085.1 - 6.4e-07 28.6 9.8 1.2e-05 24.6 1.5 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP15085.1 - 0.00018 22.0 0.1 0.0074 16.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP15085.1 - 0.016 15.5 0.1 0.075 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFP15085.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KFP15085.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KFP15085.1 - 0.077 13.2 0.0 0.3 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP15085.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KFP15085.1 - 0.11 13.0 0.0 0.62 10.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 KFP15085.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vinculin PF01044.19 KFP15085.1 - 0.18 10.0 0.2 0.3 9.3 0.2 1.2 1 0 0 1 1 1 0 Vinculin family LLGL PF08366.13 KFP15086.1 - 1e-07 32.3 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 LLGL2 Lgl_C PF08596.10 KFP15086.1 - 0.016 13.9 0.0 0.061 12.0 0.0 1.9 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal tRNA_int_end_N2 PF12928.7 KFP15087.1 - 1e-15 57.7 1.2 1.5e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term SH3_1 PF00018.28 KFP15089.1 - 6.6e-36 121.7 0.3 8.4e-17 60.5 0.1 2.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFP15089.1 - 3.8e-32 109.9 0.2 1.8e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP15089.1 - 3.1e-28 97.2 0.0 1.1e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 KFP15089.1 - 1.3e-24 86.1 0.0 2.1e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH3_10 PF17902.1 KFP15089.1 - 1.6e-06 28.0 0.0 0.00048 20.2 0.0 2.5 2 1 0 2 2 2 1 SH3 domain SH2_2 PF14633.6 KFP15089.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 SH2 domain hSH3 PF14603.6 KFP15089.1 - 0.0074 16.7 0.0 0.078 13.4 0.0 2.3 2 0 0 2 2 2 1 Helically-extended SH3 domain SH3_3 PF08239.11 KFP15089.1 - 0.0077 16.5 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain DUF5093 PF17011.5 KFP15089.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) SH3_4 PF06347.13 KFP15089.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Mito_carr PF00153.27 KFP15090.1 - 1e-66 220.9 2.6 4.5e-22 77.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mitofilin PF09731.9 KFP15090.1 - 0.37 9.6 0.0 0.48 9.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_S7 PF00177.21 KFP15091.1 - 5.5e-41 139.7 0.3 7.2e-41 139.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF719 PF05334.13 KFP15091.1 - 0.011 16.0 0.4 0.019 15.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF2288 PF10052.9 KFP15091.1 - 0.067 13.3 0.1 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) Tom5 PF10642.9 KFP15091.1 - 1 9.4 3.3 0.86 9.7 1.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase VHS PF00790.19 KFP15092.1 - 8.1e-46 155.4 2.2 2.6e-45 153.8 0.0 2.4 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFP15092.1 - 6.7e-31 106.9 0.0 6.7e-31 106.9 0.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KFP15092.1 - 4.7e-21 74.1 6.7 4.7e-21 74.1 6.7 2.0 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 KFP15092.1 - 1.5e-20 73.3 2.7 1.5e-20 73.3 2.7 2.6 2 0 0 2 2 2 1 GAT domain SesA PF17107.5 KFP15092.1 - 0.038 14.2 0.7 0.096 12.9 0.7 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HD_2 PF12917.7 KFP15092.1 - 0.044 13.5 1.3 0.092 12.5 1.3 1.5 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme HBM PF16591.5 KFP15092.1 - 0.065 12.6 1.6 0.12 11.8 1.6 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain Spc7 PF08317.11 KFP15092.1 - 0.36 9.7 7.0 0.56 9.0 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AP3B1_C PF14796.6 KFP15092.1 - 0.59 10.4 7.8 1.8 8.8 0.0 3.3 3 0 0 3 3 3 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal zf-C4H2 PF10146.9 KFP15092.1 - 1.7 8.9 11.1 4.2e+02 1.1 11.1 2.6 1 1 0 1 1 1 0 Zinc finger-containing protein PCRF PF03462.18 KFP15092.1 - 2.2 8.1 5.5 4 7.3 5.5 1.3 1 0 0 1 1 1 0 PCRF domain Cauli_AT PF03233.13 KFP15092.1 - 7.1 6.5 9.2 21 5.0 0.3 2.3 1 1 0 2 2 2 0 Aphid transmission protein Rad60-SLD PF11976.8 KFP15093.1 - 4.2e-26 90.6 0.1 5e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP15093.1 - 2.2e-12 46.5 0.1 2.6e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family JUPITER PF17054.5 KFP15094.1 - 0.00087 18.9 0.1 0.00087 18.9 0.1 1.8 2 1 1 3 3 3 1 Microtubule-Associated protein Jupiter NT5C PF06941.12 KFP15095.1 - 2.8e-18 66.4 0.0 3.1e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Arm PF00514.23 KFP15096.1 - 3e-12 46.1 0.0 3.4e-06 26.9 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 KFP15096.1 - 0.0016 17.5 0.2 0.002 17.2 0.2 1.3 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Atx10homo_assoc PF09759.9 KFP15096.1 - 0.002 18.1 0.1 0.18 11.9 0.0 2.2 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KFP15096.1 - 0.0075 15.8 0.1 1.5 8.2 0.1 2.0 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KFP15096.1 - 0.027 13.0 0.7 0.062 11.9 0.7 1.6 1 1 0 1 1 1 0 Adaptin N terminal region Glycoprotein PF03409.15 KFP15096.1 - 0.045 12.6 0.1 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein ParcG PF10274.9 KFP15096.1 - 0.059 13.5 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein HEAT_2 PF13646.6 KFP15096.1 - 0.074 13.4 0.0 2 8.8 0.0 2.3 1 1 1 2 2 2 0 HEAT repeats BTB_2 PF02214.22 KFP15097.1 - 9.7e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP15097.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain SAM_LFY PF01698.16 KFP15097.1 - 0.058 13.3 0.2 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Mt_ATP-synt_D PF05873.12 KFP15098.1 - 3.7e-67 225.0 8.0 4.2e-67 224.8 8.0 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 KFP15098.1 - 0.015 13.5 0.1 0.015 13.5 0.1 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Exonuc_VII_L PF02601.15 KFP15098.1 - 0.031 13.8 0.2 0.039 13.5 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gp-FAR-1 PF05823.12 KFP15098.1 - 0.042 14.2 5.1 0.34 11.2 5.1 2.0 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GIDA_assoc PF13932.6 KFP15098.1 - 0.042 14.0 0.3 0.06 13.5 0.3 1.2 1 0 0 1 1 1 0 GidA associated domain DUF4337 PF14235.6 KFP15098.1 - 0.088 12.9 2.9 0.11 12.6 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4265 PF14085.6 KFP15098.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) DUF4140 PF13600.6 KFP15098.1 - 0.24 11.9 2.7 2.7 8.5 0.9 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Neur_chan_LBD PF02931.23 KFP15099.1 - 8.8e-24 84.2 2.3 1e-23 83.9 2.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP15099.1 - 0.015 15.3 0.8 0.046 13.8 1.3 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RF-1 PF00472.20 KFP15100.1 - 8e-20 70.9 3.0 9.9e-20 70.6 3.0 1.0 1 0 0 1 1 1 1 RF-1 domain Orbi_VP4 PF05059.12 KFP15101.1 - 0.01 13.9 0.1 0.015 13.3 0.1 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein zf-ZPR1 PF03367.13 KFP15101.1 - 0.027 14.3 0.3 0.027 14.3 0.3 3.8 3 1 1 4 4 4 0 ZPR1 zinc-finger domain DUF3540 PF12059.8 KFP15101.1 - 0.47 10.3 12.6 0.49 10.2 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3540) Lectin_N PF03954.14 KFP15101.1 - 0.54 10.0 23.9 0.052 13.3 1.2 4.6 3 1 0 4 4 4 0 Hepatic lectin, N-terminal domain FliD_C PF07195.12 KFP15101.1 - 4.7 6.6 19.7 0.54 9.6 4.9 3.7 3 1 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.9 KFP15101.1 - 5.8 7.3 37.9 0.068 13.5 13.9 4.9 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KFP15101.1 - 6.4 5.6 49.6 0.37 9.6 17.8 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFP15101.1 - 6.8 6.7 32.7 1.9 8.5 4.9 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 KFP15101.1 - 8 5.4 34.7 1.2 8.2 11.5 3.2 3 0 0 3 3 3 0 Actin interacting protein 3 DUF1003 PF06210.11 KFP15101.1 - 9.8 6.3 16.3 1.2 9.3 2.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Hid1 PF12722.7 KFP15102.1 - 1.9e-274 912.8 0.0 2.3e-274 912.5 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KFP15102.1 - 4.7e-258 857.8 0.0 5.3e-258 857.6 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Otopetrin PF03189.13 KFP15103.1 - 1.1e-53 182.7 30.7 8.4e-23 80.9 7.1 4.5 3 1 0 4 4 4 3 Otopetrin SdpI PF13630.6 KFP15103.1 - 0.046 13.8 1.0 0.046 13.8 1.0 4.0 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF5345 PF17280.2 KFP15103.1 - 0.077 13.0 0.1 0.077 13.0 0.1 3.1 4 1 0 4 4 4 0 Family of unknown function (DUF5345) VPDSG-CTERM PF18205.1 KFP15103.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.7 2 0 0 2 2 2 0 VPDSG-CTERM motif Ank_2 PF12796.7 KFP15104.1 - 9.2e-29 99.9 0.5 1.9e-15 57.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP15104.1 - 2.3e-22 79.0 4.5 2.8e-12 46.9 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP15104.1 - 3.2e-13 49.5 2.5 3.2e-07 30.5 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFP15104.1 - 1.3e-12 47.7 1.1 4.7e-07 30.0 0.3 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP15104.1 - 1.7e-12 46.4 0.8 4.5e-05 23.5 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat SAM_1 PF00536.30 KFP15104.1 - 1.5e-10 41.3 0.1 7.7e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SR-25 PF10500.9 KFP15104.1 - 1.9 8.0 12.4 3.2 7.3 12.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FA_desaturase PF00487.24 KFP15105.1 - 3.2e-09 37.0 14.8 9e-09 35.5 14.8 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Aa_trans PF01490.18 KFP15106.1 - 1.9e-19 69.7 32.3 4.2e-11 42.2 21.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFP15106.1 - 1.3e-07 31.1 20.2 0.00069 18.8 1.4 2.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Cytomega_UL84 PF06284.11 KFP15106.1 - 0.073 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ras PF00071.22 KFP15107.1 - 6.8e-59 198.1 0.1 8e-59 197.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15107.1 - 1.7e-32 112.2 0.1 2.6e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP15107.1 - 4.9e-14 52.2 0.1 5.4e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP15107.1 - 4.3e-06 26.2 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP15107.1 - 0.00016 21.6 0.2 0.099 12.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP15107.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KFP15107.1 - 0.023 14.4 0.1 0.034 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KFP15107.1 - 0.033 13.5 0.1 0.091 12.0 0.1 1.8 1 1 0 1 1 1 0 Septin FeoB_N PF02421.18 KFP15107.1 - 0.061 12.8 0.1 0.37 10.3 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DAP3 PF10236.9 KFP15107.1 - 0.066 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KFP15107.1 - 0.076 13.4 0.1 0.16 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFP15107.1 - 0.19 12.0 0.1 2.7 8.3 0.1 2.6 1 1 0 1 1 1 0 AAA domain V-set PF07686.17 KFP15108.1 - 1.9e-07 31.3 0.1 2.2e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP15108.1 - 0.008 16.3 0.3 0.017 15.3 0.1 1.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFP15108.1 - 0.016 15.8 0.2 0.023 15.3 0.1 1.5 1 1 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 KFP15108.1 - 0.03 14.6 0.0 0.039 14.3 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP15108.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP15109.1 - 1.3e-06 28.5 0.0 1.3e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP15109.1 - 0.0026 17.9 0.0 0.0026 17.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP15109.1 - 0.048 13.7 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFP15109.1 - 0.049 13.7 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFP15109.1 - 0.19 12.4 0.0 0.19 12.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP15110.1 - 1.3e-06 28.6 0.0 1.3e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP15110.1 - 0.00075 19.6 0.0 0.00077 19.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP15110.1 - 0.013 15.6 0.0 0.013 15.6 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KFP15110.1 - 0.026 14.6 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KFP15110.1 - 0.061 13.9 0.0 0.061 13.9 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain Ig_4 PF16680.5 KFP15110.1 - 0.098 12.9 0.0 0.098 12.9 0.0 1.1 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Xylo_C PF12529.8 KFP15111.1 - 4.5e-71 238.2 0.0 6.9e-71 237.6 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 KFP15111.1 - 5.3e-55 186.6 1.7 7.2e-55 186.2 1.7 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ribosomal_L27 PF01016.19 KFP15112.1 - 1.1e-25 89.4 0.1 1.4e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ERCC4 PF02732.15 KFP15113.1 - 1.6e-12 47.9 0.7 2.4e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 ERCC4 domain BRF1 PF07741.13 KFP15113.1 - 0.61 10.5 9.1 2.2 8.7 0.9 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Radial_spoke_3 PF06098.11 KFP15113.1 - 1.3 8.2 10.7 0.052 12.8 3.6 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 U1snRNP70_N PF12220.8 KFP15113.1 - 2.2 9.0 9.0 18 6.1 0.2 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LRR_8 PF13855.6 KFP15114.1 - 1.1e-13 50.7 17.0 1.5e-10 40.6 8.3 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP15114.1 - 8.3e-11 42.0 13.5 1.9e-06 28.1 3.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP15114.1 - 0.00019 21.5 13.9 6 7.8 0.4 4.9 5 0 0 5 5 4 1 Leucine Rich Repeat Hid1 PF12722.7 KFP15114.1 - 0.0015 16.8 3.4 0.0016 16.7 3.4 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 KFP15114.1 - 0.0099 14.9 9.2 0.012 14.6 9.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) NPR3 PF03666.13 KFP15114.1 - 0.024 13.5 7.8 0.031 13.1 7.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 KFP15114.1 - 0.026 11.7 7.9 0.03 11.5 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 KFP15114.1 - 0.031 13.4 10.7 0.039 13.1 10.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) LMBR1 PF04791.16 KFP15114.1 - 0.091 11.7 3.2 0.12 11.3 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAGA_bind PF06217.12 KFP15114.1 - 0.13 12.5 11.5 0.18 12.0 11.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 KFP15114.1 - 0.15 12.2 3.5 0.18 11.9 3.5 1.3 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 KFP15114.1 - 0.28 10.1 4.2 0.51 9.2 4.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MAJIN PF15077.6 KFP15114.1 - 0.35 10.6 9.7 0.52 10.1 9.7 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Hydin_ADK PF17213.3 KFP15114.1 - 0.5 10.6 10.7 0.74 10.1 10.7 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain LRR_6 PF13516.6 KFP15114.1 - 0.56 10.4 13.5 4.1 7.7 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat CDC45 PF02724.14 KFP15114.1 - 0.75 8.0 15.7 0.96 7.7 15.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KFP15114.1 - 1 8.1 7.7 1.3 7.7 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PBP1_TM PF14812.6 KFP15114.1 - 1.3 9.4 15.8 11 6.5 15.8 2.1 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4366 PF14283.6 KFP15114.1 - 1.4 8.9 7.3 14 5.7 7.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SET PF00856.28 KFP15114.1 - 1.5 9.2 4.7 2.8 8.3 4.7 1.6 1 1 0 1 1 1 0 SET domain Borrelia_P83 PF05262.11 KFP15114.1 - 1.6 7.1 21.6 2 6.8 21.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 KFP15114.1 - 1.7 8.7 6.4 2.4 8.2 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 KFP15114.1 - 3.3 7.0 10.1 5.2 6.3 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atrophin-1 PF03154.15 KFP15114.1 - 3.8 5.7 22.1 5.3 5.2 22.1 1.4 1 0 0 1 1 1 0 Atrophin-1 family XRN_M PF17846.1 KFP15114.1 - 5.3 5.9 12.6 7.6 5.4 12.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 KFP15114.1 - 6 6.6 19.3 8.3 6.1 19.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 KFP15114.1 - 9.2 6.3 18.3 12 5.8 18.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Red1 PF07964.11 KFP15114.1 - 9.9 4.3 19.5 13 3.8 19.5 1.1 1 0 0 1 1 1 0 Rec10 / Red1 AMP-binding PF00501.28 KFP15115.1 - 1.1e-99 334.0 0.0 1.3e-99 333.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP15115.1 - 1.4e-18 67.6 0.2 3.1e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.6 KFP15116.1 - 1.6e-61 204.0 35.2 3.8e-18 65.0 0.1 5.4 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP15116.1 - 6.3e-20 70.9 24.0 4.2e-05 23.8 0.1 6.8 3 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP15116.1 - 1.3e-16 60.7 0.0 3e-06 27.2 0.0 2.7 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP15116.1 - 6.2e-09 35.2 19.6 0.068 13.8 0.0 9.6 10 1 1 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP15116.1 - 4.3e-08 32.9 6.4 0.047 13.2 0.0 3.5 1 1 1 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFP15116.1 - 4.6e-08 32.5 4.3 4.6e-08 32.5 4.3 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Rv2175c_C PF18367.1 KFP15116.1 - 0.0033 17.5 0.1 0.29 11.3 0.0 3.2 2 1 0 2 2 2 1 Rv2175c C-terminal domain of unknown function LRRCT PF01463.24 KFP15116.1 - 0.012 16.1 0.1 0.056 14.0 0.1 2.3 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain MYCBPAP PF14646.6 KFP15117.1 - 4e-136 454.4 0.9 4.7e-136 454.2 0.0 1.5 2 0 0 2 2 2 1 MYCBP-associated protein family His_Phos_2 PF00328.22 KFP15117.1 - 0.016 14.6 1.7 0.36 10.1 0.1 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) ENTH PF01417.20 KFP15118.1 - 1.6e-50 170.3 0.0 2.5e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFP15118.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFP15118.1 - 0.00037 20.3 0.2 0.0016 18.3 0.1 1.9 2 0 0 2 2 2 1 VHS domain UIM PF02809.20 KFP15118.1 - 0.0078 16.1 2.7 0.0078 16.1 2.7 3.9 4 0 0 4 4 4 2 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 KFP15119.1 - 4.8e-76 254.2 0.0 8.1e-76 253.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KFP15119.1 - 2.2e-10 40.6 0.0 5.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 KFP15119.1 - 0.079 12.5 0.6 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 KFP15119.1 - 0.08 12.0 0.0 0.74 8.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.6 KFP15119.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Ion_trans PF00520.31 KFP15120.1 - 2.7e-242 799.7 71.1 1e-76 257.4 15.9 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KFP15120.1 - 5.8e-17 61.5 70.4 1.2e-09 37.4 1.8 8.7 6 3 3 9 9 9 6 Polycystin cation channel DPM3 PF08285.11 KFP15120.1 - 0.4 10.9 6.2 4.1 7.7 0.3 3.9 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ABC_membrane PF00664.23 KFP15121.1 - 2.2e-84 283.4 31.2 7.2e-46 157.0 8.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP15121.1 - 6.6e-44 149.7 0.0 9.6e-29 100.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFP15121.1 - 2.6e-08 33.6 0.0 0.00025 20.6 0.0 3.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFP15121.1 - 1.1e-05 25.5 0.5 0.052 13.6 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP15121.1 - 9.2e-05 22.4 0.5 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFP15121.1 - 0.00015 22.2 0.4 0.047 14.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KFP15121.1 - 0.0029 17.7 1.4 0.048 13.7 0.0 3.0 3 0 0 3 3 3 1 Dynamin family AAA_22 PF13401.6 KFP15121.1 - 0.0039 17.5 0.3 5.6 7.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFP15121.1 - 0.018 14.6 0.5 0.46 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP15121.1 - 0.036 13.6 0.8 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFP15121.1 - 0.037 13.8 1.9 5.1 6.9 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KFP15121.1 - 0.12 11.9 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 KFP15121.1 - 0.16 11.1 0.9 1.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KFP15121.1 - 0.28 11.7 3.5 27 5.2 0.1 3.5 4 0 0 4 4 4 0 AAA domain PRIMA1 PF16101.5 KFP15121.1 - 1.6 8.8 6.3 0.93 9.5 0.5 3.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF87 PF01935.17 KFP15121.1 - 1.9 8.5 7.3 4.1 7.4 0.4 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain LUC7 PF03194.15 KFP15123.1 - 7.2e-76 255.2 26.8 7.2e-76 255.2 26.8 3.6 1 1 2 3 3 3 1 LUC7 N_terminus MOZART1 PF12554.8 KFP15124.1 - 0.15 11.9 0.4 0.38 10.6 0.4 1.7 1 1 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Kunitz_BPTI PF00014.23 KFP15125.1 - 5.6e-32 109.7 32.4 1.4e-20 73.3 6.7 3.1 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 KFP15125.1 - 4.6e-17 61.9 0.0 7.7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP15125.1 - 8.7e-15 55.1 0.2 2.4e-14 53.7 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain NTR PF01759.21 KFP15125.1 - 5.8e-11 42.2 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Ig_2 PF13895.6 KFP15125.1 - 8.6e-10 38.8 0.0 2.9e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP15125.1 - 1.4e-09 38.0 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP15125.1 - 2.5e-06 27.6 1.4 4.2e-05 23.7 0.1 3.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain BTG PF07742.12 KFP15126.1 - 1.4e-38 131.3 0.0 2.5e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 BTG family PAM2 PF07145.15 KFP15126.1 - 4.2e-06 26.1 3.2 0.0083 15.8 0.3 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region NDK PF00334.19 KFP15127.1 - 1.2e-54 184.0 0.0 1.3e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Benyvirus_14KDa PF07255.11 KFP15127.1 - 0.054 13.7 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Benyvirus 14KDa protein NDK PF00334.19 KFP15128.1 - 3.5e-56 188.9 0.0 4e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MBT PF02820.18 KFP15129.1 - 9.7e-92 301.4 2.3 7.3e-28 96.7 0.1 4.3 4 0 0 4 4 4 4 mbt repeat C1_2 PF03107.16 KFP15129.1 - 0.028 14.7 3.0 1.7 9.0 0.0 3.4 3 0 0 3 3 3 0 C1 domain WD40 PF00400.32 KFP15130.1 - 3.5e-08 34.0 0.0 1.4 9.9 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP15130.1 - 2.2e-07 31.0 0.0 0.31 11.4 0.0 5.1 2 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Formyl_trans_C PF02911.18 KFP15130.1 - 0.1 12.9 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain BASP1 PF05466.12 KFP15132.1 - 1.6e-96 322.9 97.0 1.8e-96 322.8 97.0 1.0 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) Reticulon PF02453.17 KFP15133.1 - 0.034 14.1 2.7 0.081 12.9 2.7 1.6 1 1 0 1 1 1 0 Reticulon Pex24p PF06398.11 KFP15133.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-C2H2_2 PF12756.7 KFP15134.1 - 8.4e-37 125.6 10.0 1.6e-29 102.2 0.3 3.4 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFP15134.1 - 4.5e-11 42.7 13.9 4.1e-07 30.1 3.8 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP15134.1 - 4.5e-05 23.7 3.4 4.5e-05 23.7 3.4 3.5 4 0 0 4 4 3 1 Zinc-finger of C2H2 type DUF4637 PF15470.6 KFP15134.1 - 0.00019 21.2 0.5 0.00044 20.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) DUF629 PF04780.12 KFP15134.1 - 0.0027 16.3 3.4 0.043 12.3 0.7 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KFP15134.1 - 0.0077 17.0 0.8 0.0077 17.0 0.8 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP15134.1 - 0.0082 16.1 1.7 0.0082 16.1 1.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-DBF PF07535.12 KFP15134.1 - 0.053 13.6 0.9 0.053 13.6 0.9 2.9 3 0 0 3 3 3 0 DBF zinc finger zf-LYAR PF08790.11 KFP15134.1 - 0.077 12.9 7.5 2.3 8.2 0.2 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DNA_pol_phi PF04931.13 KFP15134.1 - 2.4 6.2 15.7 0.024 12.8 7.0 1.8 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 KFP15134.1 - 4.5 6.5 11.1 6.3 6.0 5.9 2.5 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.16 KFP15134.1 - 8.4 5.5 9.0 0.7 9.0 4.0 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit LRR_6 PF13516.6 KFP15135.1 - 1.1e-30 103.0 2.4 0.016 15.2 0.0 10.9 11 0 0 11 11 11 8 Leucine Rich repeat F-box-like PF12937.7 KFP15135.1 - 8.1e-17 60.9 4.2 2.4e-16 59.4 4.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFP15135.1 - 1.7e-16 60.0 0.0 0.013 15.9 0.0 6.6 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) F-box PF00646.33 KFP15135.1 - 4.4e-12 45.6 1.9 4.4e-12 45.6 1.9 2.7 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 KFP15135.1 - 7.3e-12 44.1 6.6 3.1 8.7 0.0 10.3 10 1 0 10 10 10 2 Leucine Rich Repeat p25-alpha PF05517.12 KFP15136.1 - 1.1e-67 227.0 4.1 1.2e-67 226.9 4.1 1.0 1 0 0 1 1 1 1 p25-alpha Rep_3 PF01051.21 KFP15136.1 - 0.026 14.3 0.4 0.034 14.0 0.4 1.1 1 0 0 1 1 1 0 Initiator Replication protein HGD-D PF06050.13 KFP15136.1 - 0.085 12.6 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF3512 PF12024.8 KFP15137.1 - 1.6e-83 279.8 0.5 1.6e-83 279.8 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KFP15137.1 - 1.3e-24 86.1 0.0 2.3e-23 82.1 0.1 2.4 2 0 0 2 2 2 1 Bromodomain Zip PF02535.22 KFP15137.1 - 0.13 11.5 1.5 0.21 10.8 1.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 KFP15137.1 - 0.54 10.4 7.8 0.55 10.4 4.5 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 KFP15137.1 - 0.61 8.8 8.6 0.088 11.6 4.0 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 KFP15137.1 - 2.1 7.6 7.3 4.1 6.6 7.3 1.4 1 0 0 1 1 1 0 Prim-pol family 5 NARP1 PF12569.8 KFP15137.1 - 2.2 7.1 16.2 4.2 6.2 16.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SR-25 PF10500.9 KFP15137.1 - 2.9 7.4 23.3 0.044 13.4 14.7 2.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KFP15137.1 - 4.6 5.4 14.8 7.8 4.7 14.8 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.29 KFP15138.1 - 2.2e-31 109.0 0.0 3.4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP15138.1 - 4.6e-07 30.2 0.3 2.2e-06 28.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP15138.1 - 7.6e-06 26.5 0.0 3.6e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP15138.1 - 1.3e-05 25.6 0.0 2.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFP15138.1 - 3.6e-05 23.8 0.0 8.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP15138.1 - 0.00024 21.3 0.1 0.00039 20.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP15138.1 - 0.00047 19.9 0.0 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFP15138.1 - 0.00053 19.6 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP15138.1 - 0.00055 19.9 0.1 0.0017 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KFP15138.1 - 0.0012 18.6 0.7 0.0024 17.6 0.0 1.9 2 1 0 2 2 1 1 Cytidylate kinase ATPase_2 PF01637.18 KFP15138.1 - 0.0013 18.7 0.6 0.13 12.2 0.6 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KFP15138.1 - 0.0014 18.4 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KFP15138.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KFP15138.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFP15138.1 - 0.0023 18.3 0.0 0.0061 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KFP15138.1 - 0.0024 18.2 0.0 0.0067 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFP15138.1 - 0.0028 17.6 0.2 0.011 15.7 0.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_11 PF13086.6 KFP15138.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KFP15138.1 - 0.0029 16.9 0.4 0.81 8.9 0.1 2.3 1 1 0 2 2 2 1 KAP family P-loop domain Viral_helicase1 PF01443.18 KFP15138.1 - 0.0037 17.0 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KFP15138.1 - 0.0038 17.0 0.1 0.0087 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFP15138.1 - 0.0044 16.5 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 KFP15138.1 - 0.0047 16.1 0.1 0.017 14.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KFP15138.1 - 0.005 16.6 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KFP15138.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter TIP49 PF06068.13 KFP15138.1 - 0.0068 15.6 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 KFP15138.1 - 0.012 15.0 0.0 0.69 9.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KFP15138.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFP15138.1 - 0.032 13.6 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFP15138.1 - 0.038 13.4 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KFP15138.1 - 0.038 14.3 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFP15138.1 - 0.04 13.8 1.5 0.091 12.7 0.1 2.2 2 1 1 3 3 2 0 Rad17 P-loop domain AAA_2 PF07724.14 KFP15138.1 - 0.041 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) FtsK_SpoIIIE PF01580.18 KFP15138.1 - 0.044 13.1 0.1 7.5 5.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 KFP15138.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KFP15138.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 KFP15138.1 - 0.11 12.1 0.3 2.3 7.8 0.3 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.15 KFP15138.1 - 0.27 11.1 1.5 0.66 9.9 0.0 2.3 3 0 0 3 3 3 0 NTPase Endostatin PF06482.11 KFP15141.1 - 5.3e-91 305.4 0.1 5.9e-91 305.2 0.1 1.0 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF1554 PF07588.11 KFP15141.1 - 0.015 15.1 0.4 0.63 9.8 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1554) Kazal_1 PF00050.21 KFP15142.1 - 8.9e-12 44.8 21.6 0.0012 18.8 1.9 5.0 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP15142.1 - 2.9e-11 43.3 39.5 5.5e-05 23.2 4.2 5.8 4 1 1 5 5 5 3 Kazal-type serine protease inhibitor domain Ldl_recept_a PF00057.18 KFP15142.1 - 0.0055 16.9 3.1 0.0055 16.9 3.1 7.0 6 0 0 6 6 6 1 Low-density lipoprotein receptor domain class A VWC PF00093.18 KFP15142.1 - 0.01 16.1 4.5 0.01 16.1 4.5 9.6 7 3 4 11 11 11 0 von Willebrand factor type C domain DNA_pol_E_B PF04042.16 KFP15142.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RBFA PF02033.18 KFP15143.1 - 6.9e-16 58.6 0.5 1.3e-15 57.7 0.0 1.7 2 0 0 2 2 2 1 Ribosome-binding factor A 2-Hacid_dh_C PF02826.19 KFP15145.1 - 1.9e-59 200.0 0.1 3.7e-59 199.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP15145.1 - 2.3e-18 66.1 0.0 2.6e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP15145.1 - 1.9e-09 37.9 0.1 3.3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KFP15145.1 - 0.00062 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KFP15145.1 - 0.00088 19.4 0.0 0.33 11.0 0.0 2.3 2 1 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KFP15145.1 - 0.019 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 KFP15145.1 - 0.033 15.0 0.0 0.055 14.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFP15145.1 - 0.06 13.9 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KFP15145.1 - 0.063 13.5 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KFP15146.1 - 1.3e-58 197.3 0.1 1.9e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP15146.1 - 9e-20 70.7 0.1 1e-19 70.5 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP15146.1 - 1.8e-10 41.2 0.3 3.5e-10 40.3 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KFP15146.1 - 0.00051 19.4 0.0 0.00076 18.8 0.0 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KFP15146.1 - 0.00069 20.4 0.0 0.0013 19.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFP15146.1 - 0.0007 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_N PF05222.15 KFP15146.1 - 0.0035 17.6 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AdoHcyase_NAD PF00670.21 KFP15146.1 - 0.011 15.8 0.1 5.4 7.1 0.0 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KFP15146.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFP15146.1 - 0.21 11.8 2.7 0.62 10.3 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain DIM1 PF02966.16 KFP15147.1 - 5.6e-65 217.1 1.0 6.2e-65 217.0 1.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFP15147.1 - 3.2e-06 27.1 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFP15147.1 - 0.013 15.8 0.4 0.019 15.3 0.4 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 KFP15147.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like PQ-loop PF04193.14 KFP15148.1 - 3.4e-31 106.8 8.9 2e-19 69.1 0.1 3.7 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFP15148.1 - 1.6e-06 29.0 4.1 0.0052 17.6 1.0 2.5 2 1 0 2 2 2 2 ER lumen protein retaining receptor MtN3_slv PF03083.16 KFP15148.1 - 0.029 14.4 9.6 0.053 13.6 2.4 2.8 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Ion_trans PF00520.31 KFP15149.1 - 4.8e-38 130.8 3.2 6.6e-38 130.3 3.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP15149.1 - 4e-28 97.6 0.0 8.2e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP15149.1 - 1.7e-14 53.5 4.5 5.5e-14 51.9 2.3 2.5 2 0 0 2 2 2 1 Ion channel RHD_DNA_bind PF00554.22 KFP15152.1 - 8.6e-26 90.9 0.1 3.3e-25 89.0 0.1 2.0 1 1 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFP15152.1 - 1.3e-24 86.1 0.1 2.3e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain TIG PF01833.24 KFP15152.1 - 1.6e-06 28.1 0.1 6.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain PhoLip_ATPase_C PF16212.5 KFP15153.1 - 1.5e-52 178.9 19.9 1.5e-52 178.9 19.9 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP15153.1 - 5.2e-20 70.9 1.2 1.5e-19 69.4 1.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP15153.1 - 1.5e-14 54.8 0.2 2e-11 44.6 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP15153.1 - 1.3e-13 50.8 0.0 3.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP15153.1 - 1.2e-07 31.8 0.0 7.8e-07 29.1 0.0 2.3 2 1 1 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP15153.1 - 0.00064 19.5 0.0 0.0018 18.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4174 PF13778.6 KFP15153.1 - 0.1 13.1 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) zf-C2H2 PF00096.26 KFP15154.1 - 2.7e-31 106.3 73.6 5.9e-05 23.3 0.2 10.1 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15154.1 - 5.7e-30 101.4 74.1 0.00072 20.2 1.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP15154.1 - 3.8e-27 93.5 57.6 4.9e-07 29.9 1.1 10.8 11 0 0 11 11 11 7 Zinc-finger double domain zf-met PF12874.7 KFP15154.1 - 1.7e-20 72.7 52.7 0.0027 18.0 0.4 9.7 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP15154.1 - 5.5e-19 68.0 42.8 0.00096 19.4 1.0 9.8 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFP15154.1 - 0.0004 20.8 36.4 0.00045 20.6 2.9 6.6 5 3 1 6 6 6 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFP15154.1 - 0.0012 18.8 66.8 0.0075 16.2 1.6 10.0 10 0 0 10 10 10 5 C2H2-type zinc finger DUF3268 PF11672.8 KFP15154.1 - 0.0046 17.3 17.9 0.4 11.0 0.2 4.3 4 0 0 4 4 4 2 zinc-finger-containing domain zf-Di19 PF05605.12 KFP15154.1 - 0.0096 16.2 36.6 0.075 13.3 2.6 5.2 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding NinF PF05810.12 KFP15154.1 - 0.094 12.6 0.1 0.49 10.3 0.1 2.2 1 0 0 1 1 1 0 NinF protein zf-C2H2_2 PF12756.7 KFP15154.1 - 0.21 11.9 45.1 0.55 10.6 2.2 8.8 4 4 5 9 9 9 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KFP15154.1 - 0.35 11.2 6.5 16 5.9 0.1 4.3 4 0 0 4 4 4 0 BolA-like protein zf-C2H2_3rep PF18868.1 KFP15154.1 - 0.38 11.4 18.6 31 5.3 0.3 6.6 5 1 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats DUF2225 PF09986.9 KFP15154.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Yae1_N PF09811.9 KFP15158.1 - 1.7e-05 24.4 37.2 0.095 12.4 17.5 4.8 2 1 2 4 4 4 3 Essential protein Yae1, N terminal Y_Y_Y PF07495.13 KFP15159.1 - 4.4e-16 58.6 0.0 0.0033 17.3 0.0 5.2 5 0 0 5 5 5 4 Y_Y_Y domain Big_9 PF17963.1 KFP15159.1 - 4.8e-14 52.9 12.2 0.0049 17.6 0.7 4.9 4 0 0 4 4 4 4 Bacterial Ig domain PKD PF00801.20 KFP15159.1 - 2.7e-12 46.3 8.6 0.12 12.2 0.1 5.5 5 0 0 5 5 5 4 PKD domain REJ PF02010.15 KFP15159.1 - 3.2e-12 46.0 3.4 1.1e-08 34.3 0.6 3.9 1 1 2 3 3 3 3 REJ domain DUF4625 PF15418.6 KFP15159.1 - 7.3e-08 32.7 0.1 3.3 8.0 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4625) He_PIG PF05345.12 KFP15159.1 - 1.2e-06 28.5 4.7 4.9 7.4 0.0 5.7 5 0 0 5 5 5 1 Putative Ig domain DUF5013 PF16405.5 KFP15159.1 - 1.4e-05 25.4 0.1 0.1 12.8 0.0 4.5 5 0 0 5 5 4 1 Domain of unknown function (DUF5013) Wzt_C PF14524.6 KFP15159.1 - 4e-05 23.7 0.0 0.75 9.8 0.0 4.5 4 0 0 4 4 4 1 Wzt C-terminal domain DUF4998 PF16389.5 KFP15159.1 - 4.8e-05 23.0 2.1 2.2 7.9 0.0 4.8 5 0 0 5 5 5 2 Domain of unknown function MANEC PF07502.14 KFP15159.1 - 0.00092 19.4 4.0 0.00092 19.4 4.0 2.1 2 0 0 2 2 2 1 MANEC domain FixG_C PF11614.8 KFP15159.1 - 0.0042 17.3 3.5 15 5.8 0.1 4.2 4 0 0 4 4 4 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Cadherin PF00028.17 KFP15159.1 - 0.0055 17.1 1.1 40 4.7 0.0 4.3 4 0 0 4 4 4 0 Cadherin domain DUF4388 PF14332.6 KFP15159.1 - 0.041 14.1 0.0 0.93 9.8 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4388) Cadherin_5 PF17892.1 KFP15159.1 - 0.071 13.1 7.9 12 6.0 0.1 4.8 5 0 0 5 5 5 0 Cadherin-like domain Big_3_5 PF16640.5 KFP15159.1 - 0.21 11.8 8.5 38 4.6 2.7 4.8 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 3) PAN_4 PF14295.6 KFP15159.1 - 0.27 11.2 5.6 0.31 11.0 3.1 2.3 2 0 0 2 2 2 0 PAN domain DUF5011 PF16403.5 KFP15159.1 - 0.27 11.4 3.9 1.1e+02 3.0 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF5011) Invasin_D3 PF09134.10 KFP15159.1 - 0.5 10.7 4.8 42 4.5 0.7 4.3 2 1 2 4 4 4 0 Invasin, domain 3 Aldedh PF00171.22 KFP15160.1 - 1.9e-142 475.1 2.0 2.1e-142 474.9 2.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FG-GAP PF01839.23 KFP15161.1 - 1e-27 95.9 28.3 2.2e-09 37.3 1.9 5.6 4 1 0 4 4 4 4 FG-GAP repeat Zn_dep_PLPC PF00882.18 KFP15161.1 - 6.5e-24 84.9 1.8 6.5e-24 84.9 1.8 1.7 2 0 0 2 2 2 1 Zinc dependent phospholipase C VCBS PF13517.6 KFP15161.1 - 1.3e-14 54.5 9.3 3.6e-07 30.7 0.5 4.2 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 KFP15161.1 - 0.0069 15.8 2.2 0.29 10.5 0.1 3.3 3 1 1 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.6 KFP15161.1 - 0.017 15.1 0.1 13 5.9 0.0 4.1 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PliI PF16743.5 KFP15161.1 - 0.13 12.0 0.0 38 4.0 0.0 3.8 4 0 0 4 4 4 0 Periplasmic lysozyme inhibitor of I-type lysozyme CcmB PF03379.13 KFP15162.1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 CcmB protein TMEM239 PF15841.5 KFP15162.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family DCX PF03607.17 KFP15163.1 - 1.3e-40 137.3 0.0 1.2e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Neurensin PF14927.6 KFP15164.1 - 8.4e-51 171.2 0.0 1e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Neurensin DUF624 PF04854.14 KFP15164.1 - 0.09 12.9 2.0 0.3 11.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF624 Hormone_1 PF00103.20 KFP15167.1 - 2.1e-73 246.7 0.1 2.3e-73 246.5 0.1 1.0 1 0 0 1 1 1 1 Somatotropin hormone family KIAA1430 PF13879.6 KFP15167.1 - 0.13 13.1 0.0 1 10.1 0.0 2.1 2 0 0 2 2 2 0 KIAA1430 homologue UPF0004 PF00919.20 KFP15170.1 - 2.6e-21 75.5 0.0 5.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFP15170.1 - 5.2e-20 72.5 0.1 1.6e-19 70.9 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 KFP15170.1 - 1.6e-05 24.8 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Styelin PF17562.2 KFP15170.1 - 0.021 15.2 0.0 0.07 13.5 0.0 2.0 1 0 0 1 1 1 0 Styelin E2F_CC-MB PF16421.5 KFP15172.1 - 2.2e-33 114.5 0.4 3.6e-33 113.8 0.4 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFP15172.1 - 3.2e-21 75.1 0.8 6.1e-21 74.3 0.1 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain MBOAT PF03062.19 KFP15174.1 - 8.9e-31 107.5 13.4 8.9e-31 107.5 13.4 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family IBR PF01485.21 KFP15178.1 - 7.6e-19 67.7 22.0 2.4e-13 50.1 7.1 4.9 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFP15178.1 - 0.01 16.2 56.7 0.01 16.1 11.1 5.1 4 1 0 4 4 4 0 Ring finger domain zf-C3HC4_3 PF13920.6 KFP15178.1 - 5.4 7.0 57.6 4.1 7.4 3.1 5.6 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP15178.1 - 7 6.8 49.0 0.081 13.0 9.8 4.5 4 0 0 4 4 4 0 RING-type zinc-finger DEK_C PF08766.11 KFP15180.1 - 9.4e-18 63.9 0.2 2.2e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 KFP15180.1 - 6e-06 25.9 1.6 1.6e-05 24.5 0.1 2.7 2 0 0 2 2 2 1 SAP domain DUF2052 PF09747.9 KFP15180.1 - 0.028 14.5 32.3 0.16 12.1 14.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ORC6 PF05460.13 KFP15180.1 - 1.4 8.1 33.6 0.029 13.6 21.4 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) MDM1 PF15501.6 KFP15180.1 - 3 6.9 46.5 0.064 12.4 27.1 2.1 2 0 0 2 2 2 0 Nuclear protein MDM1 CDC45 PF02724.14 KFP15180.1 - 4.3 5.5 36.0 0.92 7.7 7.3 2.2 2 0 0 2 2 2 0 CDC45-like protein eIF-3c_N PF05470.12 KFP15180.1 - 9.6 4.4 27.5 0.67 8.2 3.3 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Amino_oxidase PF01593.24 KFP15181.1 - 3.2e-88 297.0 0.0 4.9e-88 296.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFP15181.1 - 1.6e-11 44.3 0.1 3.8e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CW PF07496.15 KFP15181.1 - 7.2e-11 41.9 1.9 2.8e-10 40.1 1.9 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger Thi4 PF01946.17 KFP15181.1 - 1.2e-08 34.5 0.1 6.6e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family SWIRM PF04433.17 KFP15181.1 - 4e-08 33.5 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Pyr_redox_2 PF07992.14 KFP15181.1 - 1e-06 28.2 0.1 1.4e-05 24.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP15181.1 - 1.1e-06 29.1 0.5 0.00011 22.7 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP15181.1 - 3e-06 26.6 1.2 1.4e-05 24.3 1.4 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFP15181.1 - 3.2e-06 26.1 1.5 2.6e-05 23.1 0.8 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KFP15181.1 - 5.6e-06 25.8 0.3 6.8e-05 22.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KFP15181.1 - 8.5e-06 25.2 3.4 0.00037 19.9 2.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFP15181.1 - 1.3e-05 25.0 0.0 7.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFP15181.1 - 6.3e-05 22.2 0.2 0.00011 21.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KFP15181.1 - 7e-05 22.3 0.3 0.00012 21.6 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFP15181.1 - 0.00026 20.4 0.0 0.00094 18.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFP15181.1 - 0.00057 19.1 0.7 0.00094 18.4 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFP15181.1 - 0.0033 17.4 0.6 0.1 12.6 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFP15181.1 - 0.009 15.3 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KFP15181.1 - 0.012 15.2 0.3 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain zf-C3HC4 PF00097.25 KFP15181.1 - 0.098 12.5 4.0 0.39 10.6 4.0 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Shikimate_DH PF01488.20 KFP15181.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KFP15181.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family HCBP_related PF06594.11 KFP15181.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain NAD_binding_7 PF13241.6 KFP15181.1 - 0.23 11.9 2.1 0.74 10.3 0.2 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Attractin PF08037.11 KFP15181.1 - 1 9.4 5.2 0.51 10.4 2.1 2.1 2 0 0 2 2 1 0 Attractin family zf-RING_2 PF13639.6 KFP15181.1 - 3.8 7.9 12.6 0.39 11.1 7.3 2.2 2 0 0 2 2 1 0 Ring finger domain TPMT PF05724.11 KFP15182.1 - 2.8e-70 236.4 0.0 3.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KFP15182.1 - 0.1 13.3 0.0 0.69 10.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain NHL PF01436.21 KFP15183.1 - 1.4e-23 81.7 7.0 0.00014 21.7 0.0 6.5 6 0 0 6 6 6 6 NHL repeat SGL PF08450.12 KFP15183.1 - 0.0046 16.6 0.0 0.044 13.3 0.0 2.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 KFP15183.1 - 0.42 11.2 2.7 1.3 9.6 0.2 2.9 4 0 0 4 4 4 0 PQQ-like domain Kinesin PF00225.23 KFP15184.1 - 2.8e-106 355.2 0.3 4.6e-106 354.5 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KFP15184.1 - 5.7e-30 105.0 0.0 2.4e-29 103.0 0.0 2.2 1 1 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KFP15184.1 - 1.5e-24 87.2 22.9 9.6e-20 71.5 1.8 4.4 4 1 1 5 5 5 2 Kinesin-associated CAP_GLY PF01302.25 KFP15184.1 - 2.8e-23 81.7 2.2 9.1e-23 80.1 2.2 1.9 2 0 0 2 2 2 1 CAP-Gly domain Microtub_bd PF16796.5 KFP15184.1 - 3.6e-21 75.7 0.0 9.9e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KFP15184.1 - 3e-16 59.6 0.0 1e-15 57.8 0.0 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 KFP15184.1 - 0.00012 22.3 0.1 0.0017 18.6 0.0 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFP15184.1 - 0.0061 16.9 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Dynamin_N PF00350.23 KFP15184.1 - 0.036 14.1 2.2 0.44 10.6 0.0 3.3 3 0 0 3 3 3 0 Dynamin family KMP11 PF03037.16 KFP15184.1 - 0.12 13.2 6.0 0.26 12.1 1.4 2.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 UCMA PF17085.5 KFP15184.1 - 6.7 6.7 9.1 0.28 11.2 2.0 2.4 2 0 0 2 2 2 0 Unique cartilage matrix associated protein CSN5_C PF18323.1 KFP15184.1 - 8.1 7.4 7.3 8.3 7.4 0.1 3.5 3 0 0 3 3 2 0 Cop9 signalosome subunit 5 C-terminal domain SIR2 PF02146.17 KFP15185.1 - 2.4e-49 167.6 0.0 3.8e-49 167.0 0.0 1.3 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KFP15185.1 - 0.00063 18.8 0.1 0.0023 17.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KFP15185.1 - 0.059 13.1 0.0 12 5.6 0.0 2.7 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain CLTH PF10607.9 KFP15186.1 - 4.5e-48 162.9 0.0 6.5e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFP15186.1 - 1.9e-25 89.3 0.2 4e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KFP15186.1 - 1.3e-06 28.1 0.0 3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 LisH DUF4462 PF14692.6 KFP15187.1 - 0.14 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) RVT_1 PF00078.27 KFP15188.1 - 0.0033 17.0 0.0 0.0084 15.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1640 PF07798.11 KFP15189.1 - 4.4e-57 192.9 11.7 3.7e-56 189.9 11.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Tuberin PF03542.16 KFP15189.1 - 0.019 14.1 3.1 0.045 12.9 2.6 1.8 1 1 1 2 2 2 0 Tuberin YabA PF06156.13 KFP15189.1 - 1.5 9.5 7.9 9.1 7.0 7.6 2.3 1 1 0 1 1 1 0 Initiation control protein YabA zf-RING_2 PF13639.6 KFP15190.1 - 9e-06 25.9 12.7 9e-06 25.9 12.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFP15190.1 - 0.00016 21.5 13.2 0.00016 21.5 13.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP15190.1 - 0.004 17.1 10.2 0.015 15.3 10.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP15190.1 - 0.01 15.7 13.2 0.026 14.4 13.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) JmjC PF02373.22 KFP15191.1 - 1.3e-26 93.3 0.2 8e-26 90.7 0.1 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KFP15191.1 - 4.8e-13 49.6 0.0 1.8e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KFP15191.1 - 7.6e-13 48.2 0.0 3e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 KFP15191.1 - 3.1e-08 33.9 7.1 9.9e-08 32.3 7.1 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger Dysbindin PF04440.16 KFP15192.1 - 2.1e-69 232.3 9.1 4.9e-69 231.1 9.1 1.7 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) AIP3 PF03915.13 KFP15192.1 - 0.46 9.5 13.1 0.099 11.7 9.4 1.6 2 0 0 2 2 2 0 Actin interacting protein 3 FERM_M PF00373.18 KFP15193.1 - 2.1e-17 63.6 2.1 4.4e-17 62.6 2.1 1.6 1 0 0 1 1 1 1 FERM central domain zf-C3HC4_3 PF13920.6 KFP15193.1 - 1.5e-10 40.7 20.3 4.1e-10 39.4 20.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_N PF09379.10 KFP15193.1 - 3e-09 36.7 0.0 6.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KFP15193.1 - 1.8e-05 25.1 0.0 6.8e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.6 KFP15193.1 - 0.021 14.7 21.1 0.062 13.2 21.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rab_eff_C PF04698.12 KFP15193.1 - 3.8 5.7 6.0 0.27 9.5 0.4 1.7 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus IMPDH PF00478.25 KFP15194.1 - 1.2e-75 254.6 5.8 3.9e-75 253.0 5.8 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFP15194.1 - 6.7e-05 22.1 0.6 0.00011 21.4 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AXH PF08517.12 KFP15195.1 - 3.1e-42 143.8 0.0 5.8e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) ATXN-1_C PF12547.8 KFP15195.1 - 3.3e-21 75.4 2.7 3.3e-21 75.4 2.7 3.7 3 0 0 3 3 3 1 Capicua transcriptional repressor modulator RDD PF06271.12 KFP15198.1 - 3.8e-12 46.6 5.1 1e-10 42.0 5.1 2.0 1 1 0 1 1 1 1 RDD family Nup153 PF08604.10 KFP15199.1 - 7.8e-196 651.8 44.7 7.8e-196 651.8 44.7 5.2 3 1 3 6 6 6 1 Nucleoporin Nup153-like zf-RanBP PF00641.18 KFP15199.1 - 1.5e-36 123.4 35.9 4.2e-12 45.2 2.4 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup_retrotrp_bd PF10599.9 KFP15199.1 - 7.2e-13 49.0 16.0 7.2e-13 49.0 16.0 11.8 6 2 3 9 9 9 1 Retro-transposon transporting motif Vps36-NZF-N PF16988.5 KFP15199.1 - 1.7 8.1 12.6 7.4 6.0 0.5 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Trnau1ap PF17654.1 KFP15200.1 - 1.8e-35 121.9 16.8 3e-35 121.2 16.8 1.3 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 KFP15200.1 - 5.6e-11 42.1 0.0 9.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_assoc PF14363.6 KFP15200.1 - 0.15 12.4 1.9 7.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA WD40 PF00400.32 KFP15201.1 - 1e-23 83.2 5.6 3.4e-06 27.7 0.4 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP15201.1 - 3.9e-08 33.5 1.8 0.034 14.5 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP15201.1 - 7.7e-06 25.9 0.4 0.11 12.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KFP15201.1 - 6.2e-05 23.0 0.3 0.085 12.9 0.1 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KFP15201.1 - 7.6e-05 21.8 5.0 0.0082 15.1 0.6 2.8 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP15201.1 - 0.0021 16.8 1.6 0.36 9.4 0.1 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFP15201.1 - 0.018 13.8 1.9 5.1 5.7 0.1 2.9 1 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 KFP15201.1 - 0.025 13.9 2.4 0.47 9.7 0.0 2.5 1 1 2 3 3 3 0 WD40-like domain RNA_pol_Rpc4 PF05132.14 KFP15201.1 - 4.8 7.6 7.2 12 6.3 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Tmemb_14 PF03647.13 KFP15202.1 - 5.8e-30 103.9 10.2 7.2e-30 103.6 10.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CytB6-F_Fe-S PF08802.10 KFP15202.1 - 0.055 13.5 1.8 4 7.6 0.2 2.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit ThrE PF06738.12 KFP15202.1 - 1.1 8.6 4.8 1.3 8.3 4.8 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter RabGAP-TBC PF00566.18 KFP15203.1 - 1.9e-06 27.7 4.6 4.8e-05 23.1 2.7 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DrrA_P4M PF14860.6 KFP15203.1 - 0.048 13.5 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Endothelin PF00322.17 KFP15204.1 - 6.5e-23 80.0 10.3 2.3e-19 68.7 1.4 2.5 2 0 0 2 2 2 2 Endothelin family zf-C2H2 PF00096.26 KFP15205.1 - 2.9e-18 65.2 41.1 0.00016 21.9 1.6 6.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP15205.1 - 2e-09 37.4 11.0 9.5e-07 29.0 0.6 5.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP15205.1 - 2.5e-07 31.0 35.5 0.041 14.7 1.8 6.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP15205.1 - 3.4e-06 27.2 41.1 0.013 15.7 1.4 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding NOA36 PF06524.12 KFP15205.1 - 7.8e-05 22.1 17.3 0.016 14.5 0.9 2.8 2 0 0 2 2 2 2 NOA36 protein zf-H2C2_5 PF13909.6 KFP15205.1 - 0.00094 18.9 5.8 0.00094 18.9 5.8 5.8 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-met PF12874.7 KFP15205.1 - 0.36 11.3 38.5 1.5 9.3 0.5 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Tmemb_170 PF10190.9 KFP15207.1 - 7.5e-36 122.7 12.3 8.2e-36 122.6 12.3 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Gly_kinase PF02595.15 KFP15207.1 - 0.0038 16.3 0.1 0.0041 16.2 0.1 1.0 1 0 0 1 1 1 1 Glycerate kinase family CAS_C PF12026.8 KFP15209.1 - 1.3e-81 273.7 6.8 3.4e-81 272.3 6.8 1.7 1 0 0 1 1 1 1 Crk-Associated Substrate C-terminal domain Serine_rich PF08824.10 KFP15209.1 - 7.5e-58 195.0 2.5 7.5e-58 195.0 2.5 2.5 3 0 0 3 3 3 1 Serine rich protein interaction domain SH3_9 PF14604.6 KFP15209.1 - 2.2e-13 49.8 0.0 3.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP15209.1 - 3.1e-11 42.7 0.0 5.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP15209.1 - 4.4e-11 42.3 0.0 7.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DMAP1 PF05499.12 KFP15210.1 - 4.1e-77 257.7 8.2 6.8e-77 257.0 8.2 1.4 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 KFP15210.1 - 8e-34 115.7 4.4 2.1e-33 114.3 4.4 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ATP-synt_D PF01813.17 KFP15210.1 - 0.0086 15.9 2.5 0.016 15.1 2.5 1.4 1 0 0 1 1 1 1 ATP synthase subunit D DUF2110 PF09883.9 KFP15210.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) FapA PF03961.13 KFP15210.1 - 5.8 5.4 7.8 3.3 6.2 4.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A zf-C2H2 PF00096.26 KFP15211.1 - 6.4e-13 48.4 12.4 2.1e-06 27.9 4.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15211.1 - 1.2e-07 32.0 11.6 0.0006 20.4 3.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP15211.1 - 1.5e-07 31.5 4.8 1.5e-07 31.5 4.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 KFP15211.1 - 0.029 14.7 1.8 0.03 14.6 1.8 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KFP15211.1 - 0.043 13.6 4.8 2.8 7.8 1.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Glyco_transf_7C PF02709.14 KFP15212.1 - 4.9e-32 109.4 2.0 6.5e-32 109.0 0.7 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KFP15212.1 - 2.4e-31 108.2 0.3 4e-31 107.4 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KFP15212.1 - 0.023 14.2 0.1 0.045 13.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 KFP15213.1 - 8.1e-58 193.8 0.0 1.2e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP15213.1 - 6.3e-23 80.2 1.2 1.2e-22 79.3 1.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase ATP-synt_C PF00137.21 KFP15214.1 - 2.5e-27 95.0 33.9 6.9e-14 51.9 12.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PIRT PF15099.6 KFP15214.1 - 1.7 8.2 7.4 4.7 6.8 1.0 2.3 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Diphthamide_syn PF01866.17 KFP15215.1 - 1.3e-54 185.7 0.0 4.9e-31 108.3 0.0 2.1 1 1 1 2 2 2 2 Putative diphthamide synthesis protein Importin_rep_2 PF18786.1 KFP15216.1 - 4.4e-50 167.3 11.2 1e-25 89.3 1.5 3.0 3 0 0 3 3 3 2 Importin 13 repeat Importin_rep_3 PF18806.1 KFP15216.1 - 1.4e-36 124.4 0.0 5.1e-36 122.6 0.0 2.1 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 KFP15216.1 - 2e-28 99.3 8.0 1.3e-24 86.9 0.3 4.4 4 1 0 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 KFP15216.1 - 2.1e-23 81.7 0.9 2.1e-23 81.7 0.9 2.2 3 0 0 3 3 3 1 Importin 13 repeat IBN_N PF03810.19 KFP15216.1 - 3.1e-09 36.6 1.2 1.4e-08 34.6 0.4 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain SLED PF12140.8 KFP15216.1 - 0.021 15.3 0.2 0.095 13.2 0.2 2.1 1 0 0 1 1 1 0 SLED domain Glyco_transf_29 PF00777.18 KFP15217.1 - 1.9e-69 234.0 0.0 2.4e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Y_phosphatase PF00102.27 KFP15218.1 - 8.7e-168 555.7 1.3 1.4e-85 286.7 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP15218.1 - 8e-110 359.4 29.6 5e-16 58.8 0.2 9.0 8 1 0 8 8 8 8 Fibronectin type III domain I-set PF07679.16 KFP15218.1 - 5.9e-44 148.1 0.0 4.8e-16 58.6 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP15218.1 - 8.9e-39 132.0 1.1 1.8e-12 47.6 0.0 5.2 5 0 0 5 5 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP15218.1 - 8.7e-22 77.5 22.1 0.12 13.0 0.0 10.2 9 1 0 9 9 9 7 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 KFP15218.1 - 2.3e-21 75.9 0.1 1.1e-07 32.0 0.0 4.6 4 0 0 4 4 4 3 Immunoglobulin domain Interfer-bind PF09294.10 KFP15218.1 - 6e-15 55.4 1.1 0.16 12.3 0.0 7.4 8 0 0 8 8 7 4 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.25 KFP15218.1 - 1.4e-14 54.1 0.0 0.0057 16.8 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain fn3_2 PF16893.5 KFP15218.1 - 1.2e-13 51.0 0.9 0.081 13.1 0.0 8.2 8 0 0 8 8 8 2 Fibronectin type III domain DSPc PF00782.20 KFP15218.1 - 1.3e-08 34.8 0.0 0.0037 17.1 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.17 KFP15218.1 - 2.1e-08 34.3 3.6 0.19 11.9 0.0 6.5 6 2 0 6 6 4 2 Immunoglobulin V-set domain Y_phosphatase3 PF13350.6 KFP15218.1 - 7.6e-08 32.6 0.1 0.019 14.9 0.0 3.1 3 0 0 3 3 3 2 Tyrosine phosphatase family C2-set_2 PF08205.12 KFP15218.1 - 8.1e-07 29.0 2.6 0.14 12.2 0.0 4.7 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain PTPlike_phytase PF14566.6 KFP15218.1 - 1.4e-05 25.3 0.1 0.019 15.1 0.0 3.2 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_Y_Y PF07495.13 KFP15218.1 - 2e-05 24.4 0.6 0.023 14.7 0.0 3.5 3 0 0 3 3 3 1 Y_Y_Y domain Ig_5 PF16681.5 KFP15218.1 - 5.4e-05 23.5 0.0 0.1 13.0 0.0 3.8 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFP15218.1 - 0.0006 19.8 0.0 3.9 7.6 0.0 4.4 3 1 0 3 3 3 1 C17orf99 Ig domain DUF2369 PF10179.9 KFP15218.1 - 0.00089 19.6 0.2 53 4.3 0.0 6.0 5 1 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) DUF4998 PF16389.5 KFP15218.1 - 0.012 15.2 2.4 6.5 6.3 0.0 4.9 6 1 0 6 6 6 0 Domain of unknown function Insulin_TMD PF17870.1 KFP15218.1 - 0.028 14.5 0.3 0.063 13.4 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment fn3_4 PF16794.5 KFP15218.1 - 0.031 14.2 7.1 3.5 7.6 0.0 5.8 6 0 0 6 6 6 0 Fibronectin-III type domain ICAM_N PF03921.14 KFP15218.1 - 0.11 12.3 0.0 0.46 10.2 0.0 2.2 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF3377 PF11857.8 KFP15218.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 KFP15218.1 - 3.7 7.4 6.1 0.39 10.6 0.1 2.4 3 0 0 3 3 2 0 TMEM154 protein family AP_endonuc_2 PF01261.24 KFP15219.1 - 6.2e-17 61.7 0.0 8.4e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sigma70_r4 PF04545.16 KFP15220.1 - 0.058 12.9 0.1 3.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 Med8 PF10232.9 KFP15223.1 - 7.5e-81 271.1 0.2 8.6e-81 270.9 0.2 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CSN4_RPN5_eIF3a PF18420.1 KFP15223.1 - 0.04 14.1 0.7 0.093 12.9 0.7 1.5 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Baculo_PEP_C PF04513.12 KFP15223.1 - 0.067 13.2 0.3 13 5.8 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELO PF01151.18 KFP15224.1 - 3e-64 217.0 22.3 3.7e-64 216.7 22.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Spore_YhaL PF14147.6 KFP15224.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.7 3 0 0 3 3 3 0 Sporulation protein YhaL WD40 PF00400.32 KFP15225.1 - 3.5e-25 87.8 20.0 1.3e-05 25.8 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP15225.1 - 4.3e-20 71.8 10.1 8.6e-08 32.4 1.1 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP15225.1 - 0.00053 19.1 2.6 0.06 12.3 0.8 3.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP15225.1 - 0.06 12.0 2.8 4.7 5.7 0.1 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 LRR_8 PF13855.6 KFP15226.1 - 3.5e-21 74.7 27.7 1.9e-10 40.4 4.6 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR19-TM PF15176.6 KFP15226.1 - 8.4e-20 70.7 0.0 1.3e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_4 PF12799.7 KFP15226.1 - 3.2e-07 30.6 16.4 0.0022 18.3 2.4 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP15226.1 - 0.00024 21.2 15.0 3.9 8.4 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP15226.1 - 0.00041 19.9 0.1 0.00062 19.3 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRRCT PF01463.24 KFP15226.1 - 0.026 15.0 0.7 0.11 13.0 0.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain DUF1148 PF06618.11 KFP15226.1 - 0.066 13.4 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1148) LRR_6 PF13516.6 KFP15226.1 - 0.083 13.0 11.4 14 6.0 0.2 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_5 PF13306.6 KFP15226.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) TMEM125 PF15109.6 KFP15227.1 - 1.2e-54 183.4 7.3 1.2e-54 183.4 7.3 2.0 2 0 0 2 2 2 1 TMEM125 protein family DUF4234 PF14018.6 KFP15227.1 - 0.11 12.7 0.9 4.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4231 PF14015.6 KFP15227.1 - 0.37 11.3 6.8 5.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3671 PF12420.8 KFP15227.1 - 8.5 6.5 5.9 5.7 7.1 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function WD40 PF00400.32 KFP15228.1 - 6.1e-11 42.7 12.6 0.006 17.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat CALCOCO1 PF07888.11 KFP15228.1 - 0.00045 19.2 19.3 0.00045 19.2 19.3 4.0 1 1 3 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like ANAPC4_WD40 PF12894.7 KFP15228.1 - 0.0023 18.2 0.0 3.1 8.1 0.0 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1664 PF07889.12 KFP15228.1 - 0.011 15.8 4.7 0.011 15.8 4.7 6.6 2 1 6 8 8 8 0 Protein of unknown function (DUF1664) Ebp2 PF05890.12 KFP15229.1 - 3.2e-78 263.0 30.0 3.7e-78 262.8 30.0 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Atg14 PF10186.9 KFP15229.1 - 0.1 11.7 12.0 0.14 11.2 12.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 O-antigen_lig PF13425.6 KFP15229.1 - 0.88 8.3 4.4 1.1 7.9 4.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GvpL_GvpF PF06386.11 KFP15229.1 - 0.94 9.4 8.5 0.28 11.1 4.8 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Cytochrom_B562 PF07361.11 KFP15229.1 - 2 9.1 16.6 2.3 8.9 13.6 2.2 1 1 1 2 2 2 0 Cytochrome b562 DUF4407 PF14362.6 KFP15229.1 - 3.4 6.9 11.7 4.2 6.6 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 KFP15229.1 - 4.6 6.0 9.8 5.4 5.7 9.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PIF1 PF05970.14 KFP15230.1 - 7.9e-46 156.9 0.8 1.2e-43 149.7 0.8 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KFP15230.1 - 3.7e-09 36.6 0.0 6.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFP15230.1 - 6.6e-05 22.6 0.1 0.00024 20.9 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KFP15230.1 - 0.00067 17.7 0.0 0.00096 17.2 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.6 KFP15230.1 - 0.0029 17.9 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KFP15230.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ENOD40 PF08247.11 KFP15230.1 - 4.5 7.5 5.4 4.9 7.4 0.2 2.9 2 0 0 2 2 2 0 ENOD40 protein AHJR-like PF18743.1 KFP15231.1 - 0.0031 17.1 0.6 0.0045 16.5 0.6 1.3 1 0 0 1 1 1 1 REase_AHJR-like FolB PF02152.18 KFP15231.1 - 0.42 11.2 2.3 0.36 11.4 0.3 1.9 3 0 0 3 3 3 0 Dihydroneopterin aldolase Glyco_transf_29 PF00777.18 KFP15232.1 - 9.6e-37 126.8 0.1 1.1e-36 126.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) ADK PF00406.22 KFP15233.1 - 8e-79 263.0 0.0 3.5e-42 144.0 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFP15233.1 - 4e-55 186.0 0.1 2.1e-27 96.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP15233.1 - 3.3e-19 69.7 0.1 6.6e-08 33.2 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 KFP15233.1 - 3.7e-10 40.1 0.2 0.00018 21.7 0.2 3.2 2 2 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 KFP15233.1 - 2.2e-06 27.5 6.1 0.042 13.5 0.1 4.1 4 0 0 4 4 4 2 Thymidylate kinase Cytidylate_kin PF02224.18 KFP15233.1 - 2.6e-06 27.3 1.0 0.3 10.8 0.1 3.6 3 1 1 4 4 4 2 Cytidylate kinase Hydin_ADK PF17213.3 KFP15233.1 - 3.7e-06 27.3 0.0 0.072 13.4 0.0 2.7 3 0 0 3 3 3 2 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 KFP15233.1 - 3.8e-06 26.3 0.2 0.01 15.2 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_28 PF13521.6 KFP15233.1 - 0.00057 20.2 0.1 0.34 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain dNK PF01712.19 KFP15233.1 - 0.00079 19.3 0.8 0.1 12.4 0.0 3.3 3 0 0 3 3 3 1 Deoxynucleoside kinase AAA_19 PF13245.6 KFP15233.1 - 0.00079 19.8 0.2 0.93 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Ploopntkinase3 PF18751.1 KFP15233.1 - 0.0012 18.8 0.1 0.44 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 KFP15233.1 - 0.0019 18.6 0.3 0.87 10.0 0.1 3.0 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KFP15233.1 - 0.0023 18.4 0.2 3 8.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP15233.1 - 0.0066 16.7 0.5 7 6.9 0.1 3.2 2 1 1 3 3 3 1 AAA domain CobU PF02283.16 KFP15233.1 - 0.011 15.4 0.4 8.1 6.0 0.0 3.6 4 0 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SKI PF01202.22 KFP15233.1 - 0.019 15.1 0.3 33 4.5 0.1 3.5 3 0 0 3 3 3 0 Shikimate kinase ATPase PF06745.13 KFP15233.1 - 0.07 12.5 0.4 7.4 5.8 0.0 2.8 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.9 KFP15233.1 - 0.11 11.7 0.1 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 KFP15233.1 - 0.21 11.2 0.5 8.8 5.9 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Myb_DNA-binding PF00249.31 KFP15234.1 - 4.5e-10 39.6 0.5 1.1e-09 38.3 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP15234.1 - 8.2e-06 26.0 0.1 2.6e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KFP15234.1 - 0.00037 20.2 7.9 0.00037 20.2 7.9 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type UCH PF00443.29 KFP15235.1 - 2.6e-63 213.9 0.0 2.8e-62 210.6 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFP15235.1 - 4e-25 88.3 0.3 5.5e-14 52.6 0.0 3.3 3 0 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 KFP15235.1 - 2.9e-19 69.8 0.9 2.9e-19 69.8 0.9 3.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP15235.1 - 1.5e-11 44.4 4.9 1.5e-11 44.4 4.9 3.3 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein B56 PF01603.20 KFP15236.1 - 1e-185 617.6 9.6 1.2e-185 617.5 9.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFP15236.1 - 0.033 14.1 4.9 0.67 9.8 0.6 2.9 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SBF2 PF12335.8 KFP15236.1 - 0.079 12.6 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Myotubularin protein HAD_2 PF13419.6 KFP15236.1 - 0.085 12.9 0.2 0.78 9.8 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cys_knot PF00007.22 KFP15237.1 - 4.2e-17 62.4 7.5 5e-17 62.1 7.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.15 KFP15237.1 - 0.0045 17.0 2.0 0.0071 16.4 2.0 1.3 1 1 0 1 1 1 1 DAN domain Ras PF00071.22 KFP15238.1 - 1.4e-48 164.6 0.0 1.6e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15238.1 - 1.4e-18 67.2 0.0 2.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP15238.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KFP15238.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Ion_trans PF00520.31 KFP15239.1 - 2.7e-36 125.0 10.2 3.7e-36 124.6 10.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFP15239.1 - 8.7e-17 61.3 0.0 2.6e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 KFP15239.1 - 5.1e-13 48.8 2.7 5.1e-13 48.8 2.7 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 KFP15239.1 - 5.6e-13 48.8 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.25 KFP15239.1 - 5.3e-07 29.6 0.0 1.5e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFP15239.1 - 0.00019 21.7 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Cupin_2 PF07883.11 KFP15239.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PAS_4 PF08448.10 KFP15239.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold NPV_P10 PF05531.12 KFP15239.1 - 0.031 14.7 1.5 0.11 12.9 1.5 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cupin_3 PF05899.12 KFP15239.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) TPD52 PF04201.15 KFP15239.1 - 0.2 11.3 1.3 7 6.2 0.3 2.4 2 0 0 2 2 2 0 Tumour protein D52 family UPF0730 PF15827.5 KFP15240.1 - 3e-27 94.1 7.1 5.9e-27 93.1 7.1 1.5 1 0 0 1 1 1 1 UPF0730 unknown protein family SERTA PF06031.13 KFP15240.1 - 3e-14 52.4 2.4 4.5e-14 51.8 2.4 1.3 1 0 0 1 1 1 1 SERTA motif C2 PF00168.30 KFP15241.1 - 4.8e-19 68.6 0.0 5.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 C2 domain SNAPc_SNAP43 PF09808.9 KFP15242.1 - 2.3e-44 151.6 3.8 5e-44 150.5 3.8 1.6 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Lipocalin_3 PF12702.7 KFP15242.1 - 0.048 13.7 0.3 0.34 11.0 0.1 2.4 2 1 0 2 2 2 0 Lipocalin-like HIF-1 PF11413.8 KFP15243.1 - 4.5e-16 58.0 5.2 1.1e-15 56.7 5.2 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 Pkinase PF00069.25 KFP15244.1 - 1.9e-64 217.6 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15244.1 - 4.3e-37 127.8 0.0 5.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFP15244.1 - 7.4e-09 36.2 0.2 1.3e-08 35.4 0.2 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP15244.1 - 8.8e-06 25.2 0.0 9.6e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFP15244.1 - 0.0022 17.6 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP15244.1 - 0.044 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFP15244.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFP15244.1 - 0.069 12.1 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFP15244.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family B2-adapt-app_C PF09066.10 KFP15244.1 - 0.16 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain TGF_beta PF00019.20 KFP15245.1 - 8e-28 97.5 0.0 2.5e-27 95.9 0.0 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain VWA PF00092.28 KFP15247.1 - 5.3e-10 39.8 0.0 5.9e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP15247.1 - 0.0062 17.2 0.0 0.025 15.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain LpxI_N PF17930.1 KFP15247.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain 7tm_4 PF13853.6 KFP15248.1 - 4.9e-43 147.9 16.6 5.8e-43 147.6 16.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15248.1 - 5e-27 94.9 13.4 8.6e-27 94.1 13.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP15248.1 - 0.047 13.3 13.9 0.035 13.7 12.5 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RNase_Zc3h12a PF11977.8 KFP15249.1 - 7e-55 185.1 0.1 2.7e-54 183.2 0.0 2.1 3 0 0 3 3 3 1 Zc3h12a-like Ribonuclease NYN domain DUF4392 PF14336.6 KFP15249.1 - 0.00095 18.7 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) UBA_6 PF18039.1 KFP15249.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain Peripla_BP_3 PF13377.6 KFP15249.1 - 0.099 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Sina PF03145.16 KFP15250.1 - 1.3e-88 296.2 0.1 2e-88 295.6 0.1 1.2 1 0 0 1 1 1 1 Seven in absentia protein family Lon_C PF05362.13 KFP15251.1 - 2e-79 265.9 0.0 3.2e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFP15251.1 - 9.8e-22 77.8 0.0 3.2e-21 76.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KFP15251.1 - 3.8e-15 56.3 0.2 3.8e-15 56.3 0.2 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KFP15251.1 - 5.8e-09 36.1 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP15251.1 - 4e-05 24.1 0.1 0.00042 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ChlI PF13541.6 KFP15251.1 - 8.9e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.11 KFP15251.1 - 0.00031 20.6 0.0 0.00079 19.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP15251.1 - 0.0014 18.9 0.1 0.023 14.9 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KFP15251.1 - 0.0018 17.3 0.0 0.018 14.0 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 KFP15251.1 - 0.0027 17.9 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 KFP15251.1 - 0.005 16.8 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KFP15251.1 - 0.0068 17.0 0.0 0.026 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP15251.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFP15251.1 - 0.022 14.5 0.1 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFP15251.1 - 0.025 14.8 0.4 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFP15251.1 - 0.029 14.3 0.0 0.065 13.2 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain SKI PF01202.22 KFP15251.1 - 0.036 14.2 0.6 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase Myc_N PF01056.18 KFP15251.1 - 0.11 12.3 0.5 0.2 11.5 0.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RNA_helicase PF00910.22 KFP15251.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sld5 PF05916.11 KFP15251.1 - 0.52 10.8 7.7 1 9.8 0.6 2.6 2 0 0 2 2 2 0 GINS complex protein DUF4375 PF14300.6 KFP15251.1 - 1.1 9.6 3.0 0.78 10.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_hydro_15 PF00723.21 KFP15252.1 - 1.4e-109 366.9 0.0 1.9e-109 366.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 VCBS PF13517.6 KFP15254.1 - 4.5e-17 62.4 12.6 1.8e-05 25.2 1.1 5.4 3 1 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFP15254.1 - 4e-08 33.2 11.1 0.043 13.9 0.1 5.7 6 0 0 6 6 6 3 FG-GAP repeat Phage_holin_2_4 PF16082.5 KFP15254.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like K1 PF02960.14 KFP15254.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 K1 glycoprotein CUB PF00431.20 KFP15255.1 - 1.7e-41 141.0 0.2 1.2e-26 93.2 0.0 3.0 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFP15255.1 - 1.5e-06 28.3 3.4 1.5e-06 28.3 3.4 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Arm_vescicular PF18770.1 KFP15255.1 - 0.067 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Borealin PF10512.9 KFP15256.1 - 2.5e-07 30.7 0.1 2.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Aminotran_1_2 PF00155.21 KFP15258.1 - 6.1e-32 111.2 0.0 7.1e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0547 PF10571.9 KFP15259.1 - 1.8e-05 24.7 2.8 2.7e-05 24.1 2.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Sec62 PF03839.16 KFP15259.1 - 0.27 10.7 3.8 0.3 10.6 3.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 KFP15259.1 - 0.5 9.5 3.3 0.58 9.3 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RAM PF15320.6 KFP15259.1 - 0.86 10.2 8.6 1.3 9.6 8.6 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Presenilin PF01080.17 KFP15259.1 - 1.1 8.0 6.6 1.2 7.8 6.6 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KFP15259.1 - 1.9 8.5 5.1 2.3 8.2 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.8 KFP15259.1 - 2.9 8.2 7.0 3.6 7.9 7.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Hid1 PF12722.7 KFP15259.1 - 3.5 5.6 8.3 4.1 5.4 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 KFP15259.1 - 7 5.3 10.3 7.9 5.1 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 KFP15260.1 - 2.6e-10 40.2 10.2 3.1e-09 36.6 0.5 3.1 2 1 1 3 3 3 3 Origin recognition complex subunit 6 (ORC6) Vps35 PF03635.17 KFP15261.1 - 1.2e-301 1002.6 13.2 1.4e-301 1002.4 13.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 FerA PF08165.11 KFP15261.1 - 0.022 14.7 0.2 0.12 12.4 0.2 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain 7tm_1 PF00001.21 KFP15263.1 - 4.1e-62 209.9 6.8 4.9e-62 209.6 6.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP15263.1 - 3.8e-07 29.8 13.1 0.00011 21.7 5.1 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP15263.1 - 0.049 13.4 6.7 0.027 14.2 2.2 2.1 2 0 0 2 2 2 0 Olfactory receptor DUF996 PF06195.13 KFP15263.1 - 0.26 11.6 4.8 0.14 12.4 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Beta_helix PF13229.6 KFP15264.1 - 1.1e-10 41.6 1.1 2.4e-10 40.5 1.1 1.5 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KFP15264.1 - 1.1e-07 31.4 0.3 3.1e-07 29.9 0.4 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 KFP15264.1 - 0.0027 17.6 0.6 0.061 13.2 0.6 2.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein UCR_TM PF02921.14 KFP15265.1 - 3.3e-28 97.9 1.9 4.7e-28 97.4 1.9 1.2 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFP15265.1 - 3.9e-13 49.2 0.0 9.3e-13 47.9 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Isochorismatase PF00857.20 KFP15265.1 - 0.077 13.2 0.1 1.4 9.0 0.1 2.1 1 1 0 1 1 1 0 Isochorismatase family V-set PF07686.17 KFP15267.1 - 0.0003 20.9 0.0 0.00034 20.7 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP15267.1 - 0.0074 16.3 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP15267.1 - 0.033 14.8 0.0 0.04 14.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.25 KFP15267.1 - 0.17 12.1 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain UPF0086 PF01868.16 KFP15268.1 - 1.5e-26 92.1 1.1 1.7e-26 91.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function UPF0086 FYVE PF01363.21 KFP15270.1 - 7e-18 64.5 7.3 1.3e-17 63.6 7.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFP15270.1 - 6.1e-09 36.3 0.4 1.1e-08 35.5 0.2 1.6 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFP15270.1 - 0.00014 21.7 0.5 0.0052 16.6 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFP15270.1 - 0.00054 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 KFP15270.1 - 0.0094 16.2 9.1 0.014 15.6 8.8 1.6 1 1 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 KFP15270.1 - 0.028 14.7 3.7 0.047 14.0 2.1 2.1 2 0 0 2 2 2 0 C1 domain DUF1835 PF08874.10 KFP15270.1 - 0.034 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) PH_6 PF15406.6 KFP15270.1 - 0.043 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain tRNA_bind_3 PF17176.4 KFP15270.1 - 0.091 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 tRNA-binding domain Bacteriocin_IIc PF10439.9 KFP15272.1 - 0.071 13.2 11.4 0.11 12.6 11.4 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 KFP15272.1 - 8.4 6.2 15.4 17 5.2 15.4 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper BtpA PF03437.15 KFP15273.1 - 2.9e-34 118.7 0.0 3.1e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 BtpA family Cyclin_N PF00134.23 KFP15274.1 - 2.2e-43 147.0 1.8 3.8e-43 146.3 1.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP15274.1 - 3.4e-19 69.1 0.0 8.5e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Prefoldin PF02996.17 KFP15276.1 - 4.1e-16 59.0 0.0 4.1e-16 59.0 0.0 2.2 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 KFP15276.1 - 5.2e-09 36.1 1.1 1.5e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit SIN1 PF05422.12 KFP15276.1 - 0.0012 19.4 1.1 0.0012 19.4 1.1 2.6 3 0 0 3 3 3 1 Stress-activated map kinase interacting protein 1 (SIN1) DUF3835 PF12927.7 KFP15276.1 - 0.37 11.7 0.3 0.37 11.7 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3835) DUF1639 PF07797.14 KFP15276.1 - 0.87 9.6 3.7 1.3 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Rib_recp_KP_reg PF05104.12 KFP15276.1 - 2.6 9.1 9.3 18 6.4 2.8 2.7 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region zf-C2H2_assoc PF16606.5 KFP15277.1 - 5.6e-41 138.6 21.1 3.4e-40 136.1 17.2 3.4 2 0 0 2 2 2 1 Unstructured conserved, between two C2H2-type zinc-fingers zf-C2H2 PF00096.26 KFP15277.1 - 6.7e-32 108.2 74.1 2.3e-05 24.6 4.0 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15277.1 - 1.3e-25 87.8 75.5 0.0022 18.7 2.8 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP15277.1 - 3.4e-20 71.5 82.3 6.7e-08 32.6 2.4 12.5 13 0 0 13 13 12 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP15277.1 - 1.9e-15 56.3 58.4 2.8e-07 30.1 0.9 10.1 10 0 0 10 10 10 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFP15277.1 - 8.9e-08 32.3 48.6 0.0061 16.8 1.7 7.8 6 3 1 7 7 7 5 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KFP15277.1 - 0.00038 20.2 10.0 0.7 9.7 0.1 6.0 5 2 2 7 7 7 2 GAGA factor Actin_micro PF17003.5 KFP15277.1 - 0.0068 15.6 22.6 7.5 5.6 0.2 6.0 4 2 1 5 5 5 2 Putative actin-like family Zn-ribbon_8 PF09723.10 KFP15277.1 - 0.01 15.9 33.0 0.52 10.5 3.3 6.2 5 2 1 6 6 6 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFP15277.1 - 0.014 15.7 43.0 4.3 7.7 0.1 10.0 5 3 4 9 9 9 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP15277.1 - 0.019 15.7 2.9 0.019 15.7 2.9 5.7 5 2 2 7 7 7 0 Zinc finger C2H2-type, 3 repeats DUF3268 PF11672.8 KFP15277.1 - 0.033 14.5 15.2 0.035 14.4 1.2 3.9 4 0 0 4 4 3 0 zinc-finger-containing domain CpXC PF14353.6 KFP15277.1 - 0.06 13.4 26.7 7.9 6.6 0.4 7.1 5 3 3 8 8 7 0 CpXC protein TerY_C PF15616.6 KFP15277.1 - 0.51 10.4 8.0 10 6.2 0.0 3.6 4 0 0 4 4 3 0 TerY-C metal binding domain DZR PF12773.7 KFP15277.1 - 0.54 10.3 22.5 0.14 12.2 0.4 5.4 5 1 0 5 5 5 0 Double zinc ribbon zf_C2H2_ZHX PF18387.1 KFP15277.1 - 4.2 7.1 25.3 0.61 9.8 0.4 5.8 4 2 2 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFP15280.1 - 2.6e-10 40.5 20.8 0.0063 16.8 1.2 5.2 3 2 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFP15280.1 - 1.8e-09 37.5 27.3 0.034 14.6 2.9 5.7 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15280.1 - 2.3e-08 34.2 22.0 0.062 14.2 2.6 5.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP15280.1 - 7.4e-06 25.8 21.5 0.024 14.6 2.4 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFP15280.1 - 0.00045 20.5 7.0 0.026 14.9 2.1 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP15280.1 - 0.0027 18.1 11.0 2.5 8.6 0.0 5.1 5 0 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KFP15280.1 - 0.007 16.6 14.9 0.058 13.7 0.8 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFP15280.1 - 0.037 14.1 10.1 6.4 7.0 0.1 5.0 5 0 0 5 5 5 0 Zinc ribbon domain DUF678 PF05077.12 KFP15280.1 - 0.065 13.4 3.7 20 5.4 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF678) zf-CpG_bind_C PF12269.8 KFP15280.1 - 0.07 12.9 6.4 0.35 10.6 0.4 3.2 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-C2H2_3rep PF18868.1 KFP15280.1 - 0.076 13.7 14.9 0.42 11.3 0.8 5.1 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 KFP15280.1 - 0.16 11.9 2.3 4.5 7.2 0.1 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Homeodomain PF00046.29 KFP15280.1 - 0.19 11.6 0.4 0.92 9.4 0.2 2.5 2 0 0 2 2 2 0 Homeodomain zf-C2HC_2 PF13913.6 KFP15280.1 - 0.37 10.7 1.4 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KFP15280.1 - 0.9 10.1 12.9 3.1 8.4 0.1 5.3 5 0 0 5 5 4 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 KFP15280.1 - 1.2 8.9 14.4 0.34 10.7 2.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type OTT_1508_deam PF14441.6 KFP15280.1 - 1.6 8.8 4.3 3.8 7.6 0.1 3.0 3 0 0 3 3 3 0 OTT_1508-like deaminase zf-C2H2_9 PF16293.5 KFP15280.1 - 6 6.8 11.0 4.6 7.2 0.2 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 KFP15282.1 - 2.5e-13 49.7 73.6 0.011 16.1 3.3 9.7 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15282.1 - 6.7e-13 48.3 68.8 0.0095 16.7 3.2 9.7 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP15282.1 - 1.3e-10 41.2 63.4 0.00027 21.2 2.0 11.0 12 0 0 12 12 12 6 Zinc-finger double domain DUF5069 PF16798.5 KFP15282.1 - 0.12 12.6 0.4 7.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) zf-H2C2_5 PF13909.6 KFP15282.1 - 0.13 12.0 75.3 0.03 14.1 2.7 9.5 10 0 0 10 10 10 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KFP15282.1 - 3 7.6 42.2 0.12 12.0 1.8 8.0 6 2 2 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain Dpy19 PF10034.9 KFP15283.1 - 1.2e-243 810.1 29.6 1.4e-243 809.9 29.6 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.17 KFP15284.1 - 2e-219 710.9 21.3 1.4e-19 70.4 0.0 15.4 15 0 0 15 15 15 15 Cadherin domain Laminin_G_2 PF02210.24 KFP15284.1 - 8.2e-35 120.1 0.1 1.6e-16 61.0 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP15284.1 - 2.1e-26 92.7 0.0 1.2e-12 48.1 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP15284.1 - 4.1e-13 49.4 50.9 6.2e-07 29.6 6.2 4.8 4 0 0 4 4 4 4 EGF-like domain Cadherin_C PF01049.17 KFP15284.1 - 9.4e-12 45.5 0.5 9.4e-12 45.5 0.5 1.9 2 0 0 2 2 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP15284.1 - 3e-11 43.0 0.0 0.39 10.6 0.0 8.8 9 0 0 9 9 9 1 Cadherin-like Cadherin_pro PF08758.11 KFP15284.1 - 5.6e-09 36.1 0.0 3.4e-05 23.9 0.0 5.6 5 0 0 5 5 5 1 Cadherin prodomain like Cadherin_3 PF16184.5 KFP15284.1 - 3.8e-08 33.3 18.8 0.02 14.9 0.2 9.1 11 0 0 11 11 11 3 Cadherin-like RET_CLD1 PF17756.1 KFP15284.1 - 4.8e-06 26.9 0.0 14 6.0 0.0 6.7 7 0 0 7 7 7 0 RET Cadherin like domain 1 hEGF PF12661.7 KFP15284.1 - 1.1e-05 25.9 44.9 0.0011 19.5 3.7 5.2 4 1 0 4 4 4 3 Human growth factor-like EGF Cadherin_4 PF17803.1 KFP15284.1 - 0.0021 18.6 1.5 0.0021 18.6 1.5 11.4 14 0 0 14 14 12 4 Bacterial cadherin-like domain EGF_2 PF07974.13 KFP15284.1 - 0.0022 18.3 57.0 0.0023 18.3 5.2 4.8 4 0 0 4 4 4 3 EGF-like domain Laminin_G_3 PF13385.6 KFP15284.1 - 0.0086 16.2 0.0 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily cEGF PF12662.7 KFP15284.1 - 1.5 8.8 28.0 0.72 9.8 3.7 4.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like Laminin_EGF PF00053.24 KFP15284.1 - 5.6 7.2 50.2 0.73 10.0 4.2 4.5 3 1 1 4 4 3 0 Laminin EGF domain dsDNA_bind PF01984.20 KFP15285.1 - 2.4e-30 105.1 3.4 2.7e-30 104.9 3.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Methyltransf_4 PF02390.17 KFP15285.1 - 0.045 13.2 0.3 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Putative methyltransferase Rossmann-like PF10727.9 KFP15285.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Rossmann-like domain Ank_2 PF12796.7 KFP15286.1 - 2.2e-56 188.4 12.8 9e-17 61.4 0.1 6.4 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFP15286.1 - 5.6e-53 175.2 22.3 4e-08 33.3 0.3 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFP15286.1 - 1.3e-48 162.4 11.1 1.4e-08 34.8 0.0 8.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP15286.1 - 5.1e-47 157.7 15.4 9.9e-11 42.0 0.4 8.4 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP15286.1 - 2.9e-40 131.6 12.7 7e-05 22.9 0.0 9.5 10 0 0 10 10 10 8 Ankyrin repeat VPS9 PF02204.18 KFP15286.1 - 2.9e-23 82.1 0.3 1e-22 80.3 0.3 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PEGA PF08308.11 KFP15286.1 - 0.079 12.9 0.1 2.7 8.0 0.0 3.4 4 0 0 4 4 4 0 PEGA domain Syntaxin_2 PF14523.6 KFP15287.1 - 0.0017 18.7 0.3 0.0035 17.7 0.3 1.5 1 0 0 1 1 1 1 Syntaxin-like protein Tic110 PF16940.5 KFP15287.1 - 0.0061 15.1 0.2 0.0079 14.7 0.2 1.1 1 0 0 1 1 1 1 Chloroplast envelope transporter LapD_MoxY_N PF16448.5 KFP15287.1 - 0.02 14.8 0.3 0.042 13.7 0.0 1.6 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain DUF1539 PF07560.11 KFP15287.1 - 0.051 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF3219 PF11514.8 KFP15287.1 - 0.11 12.6 0.2 0.59 10.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3219) TUDOR PF00567.24 KFP15289.1 - 7.4e-12 45.4 1.8 9.1e-12 45.1 1.8 1.1 1 0 0 1 1 1 1 Tudor domain TUDOR PF00567.24 KFP15290.1 - 1.3e-09 38.1 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Helicase_C PF00271.31 KFP15290.1 - 7e-08 32.8 0.1 6.6e-07 29.7 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP15290.1 - 6.5e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3885 PF13021.6 KFP15290.1 - 0.12 12.5 0.0 6 7.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) AA_permease_2 PF13520.6 KFP15291.1 - 9.7e-62 209.2 46.4 1.2e-61 208.8 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP15291.1 - 1.8e-25 89.5 43.7 2.4e-25 89.1 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease Pdase_M17_N2 PF18295.1 KFP15292.1 - 0.083 13.2 0.5 0.41 10.9 0.5 2.2 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Toprim_C_rpt PF13368.6 KFP15292.1 - 0.49 10.4 5.0 2 8.5 0.2 2.7 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat zf-RING_2 PF13639.6 KFP15293.1 - 7.2e-06 26.2 12.1 7.2e-06 26.2 12.1 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP15293.1 - 4.9e-05 23.3 8.1 5.1e-05 23.2 5.7 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP15293.1 - 5.5e-05 23.0 12.4 5.5e-05 23.0 12.4 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP15293.1 - 0.00078 19.3 13.8 0.00078 19.3 11.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) VIT1 PF01988.19 KFP15293.1 - 0.047 13.5 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 VIT family PND PF17949.1 KFP15294.1 - 5.6e-52 175.2 0.1 1e-51 174.4 0.0 1.4 2 0 0 2 2 2 1 FANCM pseudonuclease domain HHH_2 PF12826.7 KFP15294.1 - 2.6e-08 33.8 0.0 5.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFP15294.1 - 7.1e-05 23.3 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 KFP15294.1 - 0.023 15.3 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Rad10 PF03834.14 KFP15294.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.23 KFP15294.1 - 0.17 11.8 0.3 4.4 7.4 0.0 2.9 3 1 0 3 3 3 0 Helix-hairpin-helix motif RMI1_N PF08585.12 KFP15296.1 - 3.2e-29 102.2 2.1 2e-22 80.0 0.0 3.5 2 1 1 3 3 3 2 RecQ mediated genome instability protein SMN PF06003.12 KFP15296.1 - 1.1e-10 41.3 2.5 3.3e-10 39.7 0.0 2.6 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFP15296.1 - 6.5e-10 39.1 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain UBA PF00627.31 KFP15296.1 - 1.2e-07 31.5 0.1 2.3e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF4462 PF14692.6 KFP15299.1 - 0.19 11.2 0.1 0.45 10.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) SH3_1 PF00018.28 KFP15300.1 - 4.1e-25 87.1 14.2 8.3e-09 34.9 0.4 4.4 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 KFP15300.1 - 1.7e-23 82.1 5.9 9.9e-09 34.8 0.1 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_9 PF14604.6 KFP15300.1 - 1.4e-20 72.8 11.8 2.9e-07 30.2 0.1 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 KFP15300.1 - 2e-12 47.2 16.4 0.00015 21.9 0.2 4.5 4 0 0 4 4 4 4 Bacterial SH3 domain DUF1604 PF07713.13 KFP15300.1 - 0.056 13.3 10.6 0.9 9.4 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1604) Neuralized PF07177.12 KFP15301.1 - 2.9e-84 280.5 0.0 8.3e-41 139.5 0.0 2.1 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.6 KFP15301.1 - 7.4e-13 48.1 13.3 7.4e-13 48.1 13.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP15301.1 - 1.4e-05 24.9 11.6 1.4e-05 24.9 11.6 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP15301.1 - 0.39 10.7 21.4 0.026 14.5 14.6 2.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP15301.1 - 0.56 10.1 20.0 0.081 12.8 15.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ca_hom_mod PF14798.6 KFP15302.1 - 1.6e-93 312.5 4.8 1.8e-93 312.3 4.8 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.6 KFP15303.1 - 8.9e-87 290.4 0.9 1.1e-86 290.1 0.9 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF1218 PF06749.12 KFP15303.1 - 0.001 19.5 2.0 0.0046 17.4 0.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) Suf PF05843.14 KFP15304.1 - 1.4e-13 51.5 25.7 2.3e-09 37.7 0.6 4.1 1 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KFP15304.1 - 1.2e-10 41.7 0.0 0.00028 21.3 0.0 3.7 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFP15304.1 - 2.7e-10 40.2 5.5 0.0094 16.7 0.1 5.3 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 KFP15304.1 - 1.1e-07 31.4 5.3 0.00047 19.5 0.6 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP15304.1 - 1.6e-06 28.7 0.1 0.0082 16.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP15304.1 - 8.3e-05 22.8 3.3 0.0094 16.2 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP15304.1 - 0.0023 17.9 5.3 2.1 8.7 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat FAM124 PF15067.6 KFP15304.1 - 0.018 14.7 0.5 0.37 10.4 0.2 2.4 2 0 0 2 2 2 0 FAM124 family Ras_bdg_2 PF14847.6 KFP15304.1 - 0.057 13.8 0.9 1.9 8.9 0.1 2.6 2 0 0 2 2 2 0 Ras-binding domain of Byr2 ANAPC3 PF12895.7 KFP15304.1 - 0.36 11.1 4.1 0.66 10.2 0.6 2.8 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Insulin PF00049.18 KFP15304.1 - 1.6 9.8 6.8 0.77 10.8 0.1 3.2 2 1 0 2 2 2 0 Insulin/IGF/Relaxin family DUF4666 PF15697.5 KFP15304.1 - 7.8 7.2 8.3 2.6 8.8 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4666) ATP_synth_reg PF14960.6 KFP15305.1 - 2.4e-27 94.1 0.2 2.7e-27 94.0 0.2 1.0 1 0 0 1 1 1 1 ATP synthase regulation WD40 PF00400.32 KFP15306.1 - 1.8e-58 193.1 9.9 2.5e-11 43.9 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFP15306.1 - 4.3e-43 146.6 4.6 9.3e-43 145.6 4.6 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFP15306.1 - 1.1e-15 57.7 0.0 0.00035 20.8 0.0 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP15306.1 - 3.7e-09 35.8 0.5 0.0039 15.9 0.0 3.7 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP15306.1 - 2.8e-06 26.5 0.0 1.8 7.4 0.0 4.1 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP15306.1 - 0.0024 17.3 0.0 0.67 9.2 0.0 3.6 4 1 1 5 5 5 1 WD40-like domain RAB3GAP2_N PF14655.6 KFP15306.1 - 0.01 15.1 0.0 0.084 12.1 0.0 2.3 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus VID27 PF08553.10 KFP15306.1 - 0.039 13.0 0.3 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 KFP15306.1 - 0.067 13.2 0.1 26 4.9 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-C3HC4_2 PF13923.6 KFP15307.1 - 2.4e-10 40.0 9.1 5.2e-10 39.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP15307.1 - 1.3e-08 34.5 11.0 2.3e-08 33.7 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 KFP15307.1 - 9.6e-07 29.4 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_UBOX PF13445.6 KFP15307.1 - 1.7e-06 27.9 7.7 3.8e-06 26.8 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP15307.1 - 1.8e-05 24.9 9.8 1.8e-05 24.9 9.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFP15307.1 - 8.4e-05 22.4 8.7 0.00015 21.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP15307.1 - 0.00021 21.2 10.7 0.00047 20.0 10.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KFP15307.1 - 0.0021 17.9 2.6 0.0036 17.1 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFP15307.1 - 0.0071 16.5 6.2 0.022 14.9 4.4 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFP15307.1 - 0.01 16.0 10.4 0.021 15.0 10.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFP15307.1 - 0.1 12.4 8.4 0.21 11.5 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP15307.1 - 0.22 11.9 9.6 0.76 10.1 9.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KFP15307.1 - 0.31 10.9 5.4 0.55 10.1 5.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TackOD1 PF18551.1 KFP15307.1 - 0.48 10.1 9.9 0.18 11.5 2.4 2.5 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 DUF1272 PF06906.11 KFP15307.1 - 0.99 9.5 6.1 2.5 8.3 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 KFP15307.1 - 1.4 8.9 9.0 4.1 7.4 9.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 5_nucleotid PF05761.14 KFP15308.1 - 2.4e-176 587.2 0.0 3e-176 586.8 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase family DUF21 PF01595.20 KFP15309.1 - 2.4e-29 102.3 0.0 4.5e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFP15309.1 - 1.7e-07 31.6 0.2 0.00027 21.3 0.0 2.8 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 KFP15309.1 - 0.0036 17.3 0.0 0.0094 16.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Nrf1_DNA-bind PF10491.9 KFP15309.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Cupin_3 PF05899.12 KFP15309.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Methyltransf_31 PF13847.6 KFP15310.1 - 3e-32 111.5 0.0 5.5e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP15310.1 - 1.2e-20 74.0 0.1 4.1e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP15310.1 - 5.7e-19 68.6 0.0 1.3e-18 67.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP15310.1 - 5.9e-15 55.2 0.0 8.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFP15310.1 - 9.6e-14 51.5 0.0 2e-13 50.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP15310.1 - 1.3e-12 48.3 0.0 2.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP15310.1 - 9.8e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KFP15310.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KFP15310.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KFP15310.1 - 0.0042 16.5 0.0 0.0099 15.3 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KFP15310.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TylF PF05711.11 KFP15310.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) MetW PF07021.12 KFP15310.1 - 0.18 11.4 0.3 1.2 8.7 0.3 2.0 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW p450 PF00067.22 KFP15311.1 - 3.5e-138 461.2 0.0 4e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WBP-1 PF11669.8 KFP15312.1 - 6.5e-45 152.0 12.9 1.3e-44 151.1 12.9 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 TMIE PF16038.5 KFP15312.1 - 0.015 15.1 0.6 0.027 14.3 0.6 1.3 1 0 0 1 1 1 0 TMIE protein Mtc PF03820.17 KFP15313.1 - 1.6e-131 438.0 0.1 1.8e-131 437.9 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Arf PF00025.21 KFP15314.1 - 4.5e-72 241.1 0.0 5e-72 241.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP15314.1 - 1.8e-14 53.6 0.0 2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP15314.1 - 1.8e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFP15314.1 - 1.9e-14 53.6 0.3 1.2e-08 34.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFP15314.1 - 1.7e-13 50.5 0.0 2e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP15314.1 - 1e-12 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP15314.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP15314.1 - 4.8e-05 23.0 0.0 0.0031 17.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KFP15314.1 - 0.00018 22.0 0.0 0.00025 21.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFP15314.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KFP15314.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP15314.1 - 0.014 15.3 0.0 5.2 6.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KFP15314.1 - 0.024 14.7 0.1 0.047 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFP15314.1 - 0.046 13.6 0.0 7.4 6.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 KFP15314.1 - 0.052 13.1 0.1 0.17 11.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 KFP15314.1 - 0.06 12.9 0.1 7.8 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFP15314.1 - 0.081 11.9 0.0 2.8 6.8 0.0 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFP15314.1 - 0.11 12.8 0.1 0.81 10.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP15314.1 - 0.13 12.6 0.1 0.61 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KFP15314.1 - 0.15 12.1 0.0 4 7.5 0.0 2.1 1 1 1 2 2 2 0 Dynamin family zf-B_box PF00643.24 KFP15315.1 - 2.8e-05 24.2 7.5 6.8e-05 22.9 7.5 1.7 1 0 0 1 1 1 1 B-box zinc finger DUF4291 PF14124.6 KFP15315.1 - 0.051 13.4 2.3 0.082 12.8 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) dCache_2 PF08269.11 KFP15315.1 - 0.48 9.6 4.6 0.69 9.0 4.6 1.2 1 0 0 1 1 1 0 Cache domain Phasin PF05597.11 KFP15315.1 - 0.71 9.9 8.8 1.2 9.1 8.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1461 PF07314.11 KFP15315.1 - 1.1 9.2 3.1 1.7 8.5 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CASP_C PF08172.12 KFP15315.1 - 1.4 8.2 11.5 0.47 9.8 8.1 1.7 1 1 1 2 2 2 0 CASP C terminal OEP PF02321.18 KFP15315.1 - 1.6 8.5 8.7 2.5 7.9 8.7 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DUF3287 PF11690.8 KFP15315.1 - 2 8.2 6.6 1.1 9.0 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Exonuc_VII_L PF02601.15 KFP15315.1 - 2.1 7.8 6.7 2.8 7.4 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 KFP15315.1 - 7.8 5.9 19.5 12 5.3 18.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) SUFU_C PF12470.8 KFP15316.1 - 3.9e-83 278.5 0.0 5.2e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 KFP15316.1 - 4.1e-51 173.4 0.0 6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Actin PF00022.19 KFP15317.1 - 5.1e-128 427.2 0.0 2.5e-127 424.9 0.0 1.8 1 1 0 1 1 1 1 Actin MFS_2 PF13347.6 KFP15318.1 - 7.1e-22 77.6 19.3 2e-19 69.5 19.3 2.8 1 1 0 1 1 1 1 MFS/sugar transport protein FAM178 PF14816.6 KFP15321.1 - 2.3e-148 494.1 6.9 3.2e-148 493.7 6.9 1.1 1 0 0 1 1 1 1 Family of unknown function, FAM178 TerB_C PF15615.6 KFP15321.1 - 0.97 9.7 6.5 1.1 9.6 5.2 1.6 1 1 0 1 1 1 0 TerB-C domain Sema PF01403.19 KFP15322.1 - 1.8e-148 494.9 0.0 2.4e-148 494.5 0.0 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP15322.1 - 2.4e-05 24.8 4.1 2.4e-05 24.8 4.1 2.0 2 0 0 2 2 2 1 Plexin repeat PSI_integrin PF17205.3 KFP15322.1 - 0.37 10.6 3.0 0.98 9.2 3.0 1.7 1 0 0 1 1 1 0 Integrin plexin domain L51_S25_CI-B8 PF05047.16 KFP15323.1 - 1.4e-08 34.5 0.0 3.6e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA_25 PF13481.6 KFP15324.1 - 6.9e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP15324.1 - 5.4e-06 26.9 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KFP15324.1 - 3.6e-05 23.2 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain T2SSE PF00437.20 KFP15324.1 - 0.00012 21.3 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFP15324.1 - 0.00033 20.3 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFP15324.1 - 0.00055 20.5 0.0 0.00082 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFP15324.1 - 0.0019 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KFP15324.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP15324.1 - 0.016 15.3 0.0 0.041 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFP15324.1 - 0.024 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFP15324.1 - 0.036 14.1 0.0 0.074 13.1 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KFP15324.1 - 0.038 14.5 0.1 0.068 13.7 0.1 1.4 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 KFP15324.1 - 0.053 13.0 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 KFP15324.1 - 0.057 13.0 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KFP15324.1 - 0.057 13.8 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP15324.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFP15324.1 - 0.069 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP15324.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KFP15324.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PDZ PF00595.24 KFP15325.1 - 4.5e-12 46.1 0.2 4.8e-12 46.1 0.2 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP15325.1 - 1.3e-05 24.9 0.3 5.1e-05 23.0 0.3 1.8 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP15326.1 - 3.8e-36 123.3 1.4 1.9e-17 63.4 0.4 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP15326.1 - 2.6e-22 78.4 0.4 5.7e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP15326.1 - 3.9e-13 49.5 0.4 2.9e-05 24.3 0.0 2.5 2 1 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 KFP15326.1 - 0.0048 16.8 0.5 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain Mtc PF03820.17 KFP15327.1 - 2.3e-152 506.5 0.1 2.6e-152 506.3 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.32 KFP15328.1 - 9.8e-40 133.8 18.6 2.3e-06 28.2 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KFP15328.1 - 3.7e-24 84.3 4.0 7.3e-24 83.4 4.0 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.7 KFP15328.1 - 1.7e-10 40.6 0.5 5e-10 39.1 0.2 2.0 1 1 1 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KFP15328.1 - 2.7e-09 37.2 2.1 0.06 13.7 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFP15328.1 - 6.7e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFP15328.1 - 5.6e-06 25.9 0.3 0.0038 16.6 0.1 2.4 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 KFP15328.1 - 6.5e-05 21.8 6.8 0.094 11.3 0.2 4.6 3 1 2 5 5 5 2 Nucleoporin Nup120/160 F-box_5 PF18511.1 KFP15328.1 - 0.0062 16.1 0.1 0.019 14.6 0.1 1.9 1 0 0 1 1 1 1 F-box eIF2A PF08662.11 KFP15328.1 - 0.039 13.8 0.0 4.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4508 PF14969.6 KFP15328.1 - 0.065 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF5046 PF16465.5 KFP15328.1 - 0.072 12.5 0.2 5.5 6.3 0.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5046) 120_Rick_ant PF12574.8 KFP15328.1 - 0.12 11.5 0.1 0.58 9.3 0.0 1.9 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen Sugar_tr PF00083.24 KFP15329.1 - 2.8e-106 356.1 20.7 3.1e-106 355.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP15329.1 - 1.3e-13 50.7 37.1 3.4e-09 36.1 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BChl_A PF02327.17 KFP15329.1 - 0.05 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein DNA_pol_B_palm PF14792.6 KFP15330.1 - 9.8e-36 122.4 0.0 3e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KFP15330.1 - 2.3e-21 75.3 0.1 5.3e-20 71.0 0.4 2.6 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFP15330.1 - 2.5e-20 72.4 0.0 5.8e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KFP15330.1 - 4.1e-19 68.7 0.0 9.2e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFP15330.1 - 9.3e-05 23.0 0.0 0.13 12.9 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain Cdd1 PF11731.8 KFP15330.1 - 0.04 14.2 0.0 8.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Pathogenicity locus NTP_transf_2 PF01909.23 KFP15330.1 - 0.044 14.1 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH PF00633.23 KFP15330.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-LYAR PF08790.11 KFP15330.1 - 0.13 12.2 0.3 0.35 10.8 0.3 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger HHH_2 PF12826.7 KFP15330.1 - 0.19 11.8 0.0 0.72 10.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif DPCD PF14913.6 KFP15331.1 - 9.3e-85 282.8 0.4 1e-84 282.6 0.4 1.0 1 0 0 1 1 1 1 DPCD protein family Mcl1_mid PF12341.8 KFP15331.1 - 0.027 13.8 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFP15332.1 - 2.7e-14 53.3 19.2 0.00019 22.2 0.1 6.7 5 1 1 6 6 6 5 WD domain, G-beta repeat FGF PF00167.18 KFP15333.1 - 9.6e-43 145.3 1.0 1.3e-42 144.8 1.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP15333.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Fascin domain Nucleoplasmin PF03066.15 KFP15334.1 - 5.8e-34 116.7 0.0 6.3e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain Nitrophorin PF02087.15 KFP15334.1 - 0.00074 19.6 0.1 0.00083 19.4 0.1 1.1 1 0 0 1 1 1 1 Nitrophorin DUF1741 PF08427.10 KFP15335.1 - 2.9e-84 282.4 6.1 5.7e-84 281.4 6.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF4897 PF16238.5 KFP15335.1 - 0.014 15.3 1.5 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) HPS6 PF15702.5 KFP15336.1 - 0 1021.6 4.7 0 1021.4 4.7 1.0 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein Prominin PF05478.11 KFP15337.1 - 3.6e-99 332.8 0.2 4.1e-99 332.7 0.2 1.0 1 0 0 1 1 1 1 Prominin SMC_ScpA PF02616.14 KFP15337.1 - 0.0045 16.9 0.1 0.0074 16.2 0.1 1.4 1 0 0 1 1 1 1 Segregation and condensation protein ScpA Exonuc_VII_L PF02601.15 KFP15337.1 - 0.25 10.9 1.8 0.33 10.5 1.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LIM_bind PF01803.16 KFP15338.1 - 3.5e-54 183.9 9.0 3.1e-42 144.8 1.6 2.7 2 1 1 3 3 3 2 LIM-domain binding protein LID PF17916.1 KFP15338.1 - 1.7e-18 65.9 2.5 3e-18 65.2 2.5 1.4 1 0 0 1 1 1 1 LIM interaction domain (LID) HTH_psq PF05225.16 KFP15340.1 - 1.4e-14 53.5 0.1 3.7e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF4553 PF15090.6 KFP15341.1 - 5e-191 635.8 53.4 7e-160 533.1 17.7 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4553) LRR_8 PF13855.6 KFP15342.1 - 1.2e-95 313.2 83.0 4.2e-14 52.0 0.0 10.1 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 KFP15342.1 - 3.7e-40 135.2 52.2 2e-06 28.0 0.1 11.1 10 1 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP15342.1 - 6.9e-37 126.3 6.4 4e-10 39.7 0.1 5.2 4 1 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRRNT PF01462.18 KFP15342.1 - 5.4e-23 80.1 30.1 8e-09 35.0 1.5 5.7 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 KFP15342.1 - 6.8e-23 81.0 15.9 0.0022 17.5 0.0 6.1 4 2 2 6 6 6 6 Leucine-rich repeat Laminin_G_2 PF02210.24 KFP15342.1 - 2.8e-21 76.4 0.0 5.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.24 KFP15342.1 - 4e-21 73.8 10.1 0.00065 20.0 0.0 6.2 5 0 0 5 5 4 4 Leucine rich repeat C-terminal domain Laminin_G_1 PF00054.23 KFP15342.1 - 4.2e-20 72.3 0.0 7.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.27 KFP15342.1 - 1.1e-15 57.5 85.2 9.5e-07 29.0 6.2 8.1 9 0 0 9 9 7 4 EGF-like domain hEGF PF12661.7 KFP15342.1 - 1.5e-07 31.8 16.2 4.5e-05 23.9 3.3 9.0 10 0 0 10 10 7 4 Human growth factor-like EGF LRR_1 PF00560.33 KFP15342.1 - 2.2e-06 27.4 48.7 0.52 11.1 0.0 13.9 15 3 1 16 16 13 5 Leucine Rich Repeat EGF_CA PF07645.15 KFP15342.1 - 0.0051 17.0 10.7 0.0051 17.0 10.7 7.9 7 1 2 9 9 6 1 Calcium-binding EGF domain TPKR_C2 PF16920.5 KFP15342.1 - 0.019 15.1 26.0 0.029 14.5 0.4 6.5 7 0 0 7 7 6 0 Tyrosine-protein kinase receptor C2 Ig-like domain Laminin_G_3 PF13385.6 KFP15342.1 - 0.28 11.3 0.8 0.42 10.7 0.2 1.6 2 0 0 2 2 1 0 Concanavalin A-like lectin/glucanases superfamily Asparaginase PF00710.20 KFP15343.1 - 2.6e-60 203.2 0.0 2.1e-59 200.3 0.0 2.1 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFP15343.1 - 4.3e-30 104.3 0.0 8.4e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 KFP15343.1 - 1.4e-15 57.4 0.1 2.5e-10 40.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP15343.1 - 1.7e-13 50.9 0.0 6.1e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP15343.1 - 1.9e-10 40.7 0.0 2.1e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP15343.1 - 2.4e-09 37.2 0.0 3.7e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP15343.1 - 2.9e-09 36.4 0.2 8.3e-05 22.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat FH2 PF02181.23 KFP15348.1 - 1.6e-78 264.5 14.6 2.6e-78 263.8 14.6 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFP15348.1 - 1e-31 110.1 5.2 1e-31 110.1 5.2 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFP15348.1 - 5.6e-17 61.9 0.3 5.6e-17 61.9 0.3 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.12 KFP15348.1 - 1.2e-09 38.1 74.4 2.1e-09 37.3 74.4 1.3 1 0 0 1 1 1 1 Formin Homology Region 1 WH2 PF02205.20 KFP15348.1 - 0.00018 21.2 0.1 0.00051 19.8 0.1 1.8 1 0 0 1 1 1 1 WH2 motif CDT1 PF08839.11 KFP15348.1 - 0.0045 17.3 1.9 0.017 15.5 1.9 2.0 1 1 0 1 1 1 1 DNA replication factor CDT1 like Adenylsucc_synt PF00709.21 KFP15350.1 - 9.6e-163 542.0 0.0 1.1e-162 541.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase hSac2 PF12456.8 KFP15350.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol phosphatase DUF5442 PF17514.2 KFP15350.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5442) MBF1 PF08523.10 KFP15350.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Multiprotein bridging factor 1 Siva PF05458.12 KFP15352.1 - 5.6e-21 75.0 25.1 5.9e-21 74.9 25.1 1.0 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Pkinase PF00069.25 KFP15353.1 - 1.5e-78 263.8 0.0 2e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15353.1 - 9e-36 123.5 0.0 1.3e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFP15353.1 - 1.1e-11 45.1 0.1 2.6e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 KFP15353.1 - 1.3e-10 41.8 3.3 3.4e-10 40.5 3.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP15353.1 - 9.3e-09 35.0 0.0 8e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KFP15353.1 - 0.043 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.6 KFP15353.1 - 0.069 13.6 0.3 0.39 11.2 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain APH PF01636.23 KFP15353.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.31 KFP15354.1 - 2.6e-26 92.0 0.6 4.3e-26 91.3 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP15354.1 - 1.2e-13 50.6 31.1 0.00022 21.8 2.9 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP15354.1 - 6.2e-13 48.4 31.8 0.00054 20.3 1.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP15354.1 - 1.6e-12 47.2 26.7 2.6e-07 30.8 1.3 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 KFP15354.1 - 3.5e-05 24.0 13.8 0.0061 16.9 0.1 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP15354.1 - 4.7e-05 23.5 0.8 0.0094 16.2 0.0 4.5 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP15354.1 - 0.0018 18.2 21.3 0.055 13.5 0.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KFP15354.1 - 0.0056 17.1 2.7 0.0056 17.1 2.7 3.3 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFP15354.1 - 0.056 13.3 6.4 0.53 10.1 0.2 3.4 2 1 1 3 3 3 0 GAGA factor zf-C2H2_11 PF16622.5 KFP15354.1 - 0.063 13.0 0.6 0.063 13.0 0.6 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-LYAR PF08790.11 KFP15354.1 - 1.2 9.1 9.8 5 7.1 0.2 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 KFP15354.1 - 3.3 7.9 15.3 7.4 6.8 0.6 4.9 3 1 2 5 5 5 0 Zic proteins zinc finger domain FYVE PF01363.21 KFP15354.1 - 3.7 7.7 17.2 1.5 9.0 2.8 3.9 2 1 2 4 4 4 0 FYVE zinc finger CENP-B_dimeris PF09026.10 KFP15354.1 - 8 6.9 7.6 6.2 7.3 0.2 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CEP170_C PF15308.6 KFP15356.1 - 0 1023.7 56.6 0 1023.7 56.6 2.9 2 0 0 2 2 2 1 CEP170 C-terminus FHA PF00498.26 KFP15356.1 - 5.6e-18 65.0 0.2 1.5e-17 63.7 0.2 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP15356.1 - 1.7e-09 37.9 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Transposase_22 PF02994.14 KFP15356.1 - 0.021 15.0 0.8 0.066 13.4 0.8 1.8 1 0 0 1 1 1 0 L1 transposable element RBD-like domain Syntaxin_2 PF14523.6 KFP15356.1 - 1.6 9.1 12.5 3.6 8.0 2.7 4.6 4 0 0 4 4 4 0 Syntaxin-like protein PLDc_3 PF13918.6 KFP15357.1 - 4.1e-36 124.3 0.0 6.5e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 KFP15357.1 - 3.7e-24 85.1 0.7 3.6e-12 46.3 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFP15357.1 - 2.6e-12 46.3 4.0 1.7e-08 34.3 0.7 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif LEA_3 PF03242.13 KFP15358.1 - 0.034 14.9 0.1 0.14 12.9 0.1 2.1 1 0 0 1 1 1 0 Late embryogenesis abundant protein Ion_trans PF00520.31 KFP15365.1 - 1.3e-28 99.9 11.9 1.8e-28 99.4 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP15365.1 - 7.7e-28 96.7 0.1 2.2e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 KFP15365.1 - 2.5e-13 49.3 14.9 4.4e-13 48.5 14.9 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 KFP15365.1 - 0.0011 19.1 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP15365.1 - 0.016 15.1 4.0 0.016 15.1 4.0 2.8 3 0 0 3 3 3 0 Ion channel PKD_channel PF08016.12 KFP15365.1 - 0.058 12.1 9.6 0.043 12.5 8.1 1.4 1 1 0 1 1 1 0 Polycystin cation channel DUF3399 PF11879.8 KFP15366.1 - 1.6e-42 144.0 10.4 1.6e-42 144.0 10.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFP15366.1 - 2.1e-06 27.1 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP15366.1 - 0.001 19.0 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Ion channel Tetraspanin PF00335.20 KFP15367.1 - 1e-32 113.7 7.4 1.2e-32 113.5 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KFP15367.1 - 0.34 10.5 5.4 0.11 12.1 2.4 1.6 2 0 0 2 2 2 0 SUR7/PalI family MLANA PF14991.6 KFP15367.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.5 3 0 0 3 3 3 0 Protein melan-A MscS_TM PF12794.7 KFP15367.1 - 2.3 7.0 8.2 0.42 9.4 4.5 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 ING PF12998.7 KFP15371.1 - 6.5e-16 58.8 2.8 1.8e-15 57.3 2.8 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP15371.1 - 1.4e-06 28.1 7.3 2.8e-06 27.1 7.3 1.5 1 0 0 1 1 1 1 PHD-finger Pet100 PF09803.9 KFP15371.1 - 0.074 13.6 1.3 0.2 12.2 1.3 1.7 1 0 0 1 1 1 0 Pet100 SAICAR_synt PF01259.18 KFP15371.1 - 0.12 11.9 1.0 0.19 11.3 1.0 1.2 1 0 0 1 1 1 0 SAICAR synthetase zf-HC5HC2H PF13771.6 KFP15371.1 - 0.14 12.4 2.0 0.37 11.1 2.0 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP15371.1 - 0.29 10.7 3.0 0.57 9.8 3.0 1.5 1 0 0 1 1 1 0 PHD-finger Y_phosphatase PF00102.27 KFP15373.1 - 3.3e-146 485.0 5.9 4.3e-86 288.3 1.3 2.6 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.21 KFP15373.1 - 1.1e-73 247.9 0.1 2e-73 247.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.21 KFP15373.1 - 8.7e-13 48.4 0.1 3.6e-12 46.5 0.1 2.2 1 0 0 1 1 1 1 Fibronectin type III domain DSPc PF00782.20 KFP15373.1 - 0.00078 19.3 1.7 0.021 14.7 0.0 3.5 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP15373.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP15373.1 - 0.057 13.5 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Sacchrp_dh_C PF16653.5 KFP15375.1 - 1.8e-80 270.9 0.0 4.3e-80 269.6 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KFP15375.1 - 3e-27 95.6 0.3 2e-26 92.9 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KFP15375.1 - 5.4e-24 84.9 0.1 9.6e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KFP15375.1 - 4.3e-08 32.7 0.0 4.2e-05 22.9 0.0 3.2 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFP15375.1 - 0.00036 20.6 0.1 0.00077 19.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KFP15375.1 - 0.0019 17.6 0.5 0.0056 16.1 0.1 1.8 1 1 1 2 2 2 1 ThiF family NAD_binding_10 PF13460.6 KFP15375.1 - 0.0028 17.6 0.0 0.0057 16.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF2325 PF10087.9 KFP15375.1 - 0.047 13.8 0.3 0.14 12.3 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) zf-H2C2_2 PF13465.6 KFP15376.1 - 1.2e-15 57.1 24.5 5.5e-06 26.6 0.2 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP15376.1 - 4.4e-11 42.6 35.6 0.00017 21.8 1.3 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15376.1 - 4.3e-06 27.1 32.3 0.025 15.4 1.4 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP15376.1 - 0.0043 17.0 22.8 0.0044 17.0 3.0 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger BolA PF01722.18 KFP15376.1 - 0.075 13.3 4.0 2.7 8.3 0.1 2.7 3 0 0 3 3 2 0 BolA-like protein Zn-ribbon_8 PF09723.10 KFP15376.1 - 0.29 11.3 9.1 0.24 11.6 3.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 KFP15376.1 - 0.64 10.0 3.2 4.3 7.4 1.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 KFP15376.1 - 0.71 10.1 14.3 0.51 10.5 1.4 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger Zf_RING PF16744.5 KFP15376.1 - 0.9 9.7 8.1 0.64 10.2 0.3 2.9 2 1 1 3 3 3 0 KIAA1045 RING finger zinc_ribbon_9 PF14369.6 KFP15376.1 - 1.2 9.5 7.0 1.8 8.9 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon C1_2 PF03107.16 KFP15376.1 - 1.4 9.3 15.3 4.2 7.8 1.0 4.0 3 1 1 4 4 4 0 C1 domain zf-Di19 PF05605.12 KFP15376.1 - 2.4 8.5 14.6 5.1 7.5 8.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFP15376.1 - 2.8 8.5 13.6 19 5.8 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Sec23_Sec24 PF04810.15 KFP15376.1 - 3 8.0 9.1 4.6 7.4 2.1 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zf-Mss51 PF13824.6 KFP15376.1 - 9.8 6.4 11.2 5.5e+02 0.8 7.9 3.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1041 PF06292.17 KFP15377.1 - 3.5e-30 104.5 2.6 1.1e-29 102.9 2.6 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.29 KFP15377.1 - 5.3e-09 36.5 0.0 1.2e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 PH domain ATP-synt_S1 PF05827.12 KFP15379.1 - 6.5e-53 178.5 0.0 1.1e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ETC_C1_NDUFA5 PF04716.14 KFP15380.1 - 9.5e-27 92.6 0.4 1.4e-26 92.0 0.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Complex1_LYR PF05347.15 KFP15380.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Ank_2 PF12796.7 KFP15381.1 - 6.2e-51 170.9 9.8 1.5e-12 48.0 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP15381.1 - 3.3e-43 145.5 3.3 1e-07 32.3 0.0 8.2 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP15381.1 - 2.9e-39 128.6 6.8 0.0013 19.0 0.2 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KFP15381.1 - 2.5e-28 97.7 11.6 1.3e-06 28.6 0.1 9.4 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KFP15381.1 - 1.9e-25 88.1 13.8 0.04 14.4 0.0 10.8 11 0 0 11 11 11 8 Ankyrin repeat SOCS_box PF07525.16 KFP15381.1 - 9.8e-12 45.0 6.6 2.6e-10 40.5 9.0 2.1 2 0 0 2 2 2 1 SOCS box CdAMP_rec PF06153.11 KFP15381.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Cyclic-di-AMP receptor WH1 PF00568.23 KFP15382.1 - 5e-36 123.0 0.1 7.3e-36 122.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KFP15382.1 - 1.5e-18 66.9 0.4 3.9e-18 65.6 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.20 KFP15382.1 - 1.2e-16 59.9 1.7 1.6e-07 30.9 0.1 2.6 2 0 0 2 2 2 2 WH2 motif DUF4918 PF16265.5 KFP15382.1 - 0.082 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) PQQ PF01011.21 KFP15382.1 - 0.092 12.7 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat Glyco_hydro_56 PF01630.18 KFP15383.1 - 3.6e-148 493.0 1.0 4.2e-148 492.8 1.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.27 KFP15383.1 - 0.0072 16.6 2.6 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFP15383.1 - 0.27 11.6 7.6 0.48 10.9 0.7 2.5 2 0 0 2 2 2 0 EGF-like domain Arf PF00025.21 KFP15385.1 - 1.3e-38 132.2 0.0 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP15385.1 - 1.2e-12 47.7 0.0 1.4e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15385.1 - 2.9e-10 40.4 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFP15385.1 - 3e-06 26.7 0.0 3.6e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP15385.1 - 3.9e-05 23.1 0.0 4.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP15385.1 - 0.021 14.9 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase POT1PC PF16686.5 KFP15388.1 - 3.2e-40 137.6 0.0 1.8e-38 131.9 0.0 3.1 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFP15388.1 - 2.1e-34 118.4 0.1 6.8e-34 116.8 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KFP15388.1 - 8.9e-07 28.8 1.5 6.1 6.9 0.0 5.6 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 KFP15388.1 - 0.00098 19.0 0.0 0.0038 17.1 0.0 2.0 2 0 0 2 2 2 1 Replication protein A OB domain SSB PF00436.25 KFP15388.1 - 0.12 12.4 0.0 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Single-strand binding protein family ANF_receptor PF01094.28 KFP15393.1 - 1.3e-91 307.3 0.0 1.7e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP15393.1 - 5.6e-61 206.3 16.4 9.6e-61 205.5 16.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP15393.1 - 7.6e-13 48.2 11.4 1.7e-12 47.1 11.4 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP15393.1 - 0.00037 20.3 0.0 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein zf-C2H2_assoc2 PF16624.5 KFP15394.1 - 1.5e-28 99.6 31.6 1.4e-22 80.5 16.5 5.2 5 2 1 6 6 5 2 Unstructured region upstream of a zinc-finger zf-C2H2 PF00096.26 KFP15394.1 - 2.4e-16 59.2 57.5 0.0023 18.3 1.6 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15394.1 - 2.3e-15 56.0 56.1 0.0096 16.7 1.3 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP15394.1 - 6.4e-14 51.4 11.5 7.8e-14 51.1 5.0 6.6 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-met PF12874.7 KFP15394.1 - 6.1e-07 29.6 23.1 0.0027 18.0 0.6 6.5 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFP15394.1 - 2.4e-06 27.8 34.0 0.017 15.5 1.7 7.1 6 1 1 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KFP15394.1 - 1.5e-05 24.6 33.8 4.7e-05 23.0 0.6 6.5 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFP15394.1 - 1.5e-05 25.1 28.4 0.00084 19.6 1.4 5.7 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP15394.1 - 0.00041 20.6 1.4 0.00041 20.6 1.4 7.6 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KFP15394.1 - 0.0025 17.6 9.8 7.6 6.5 0.0 4.8 5 0 0 5 5 5 2 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KFP15394.1 - 0.0073 16.6 3.8 0.0073 16.6 3.8 4.2 5 1 0 5 5 5 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KFP15394.1 - 0.016 15.6 0.4 0.016 15.6 0.4 10.2 11 1 0 11 11 9 0 Zinc-finger double domain Vps39_2 PF10367.9 KFP15394.1 - 0.018 15.5 3.8 0.018 15.5 3.8 4.5 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_6 PF13912.6 KFP15394.1 - 0.061 13.3 0.6 0.061 13.3 0.6 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger CpXC PF14353.6 KFP15394.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.8 4 1 0 4 4 4 0 CpXC protein zf-C2H2_12 PF18658.1 KFP15394.1 - 0.32 10.6 15.3 0.16 11.6 0.8 5.0 5 0 0 5 5 5 0 Zinc-finger C2H2-type DUF4535 PF15054.6 KFP15394.1 - 2.6 7.9 4.5 7.2 6.4 4.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DUF2256 PF10013.9 KFP15394.1 - 7.6 6.7 20.2 12 6.2 0.0 5.4 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) RVT_1 PF00078.27 KFP15395.1 - 0.0012 18.4 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plexin_cytopl PF08337.12 KFP15397.1 - 2.8e-221 736.0 12.2 6.1e-221 734.9 12.2 1.6 1 1 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KFP15397.1 - 4.3e-64 216.9 1.3 4.3e-64 216.9 1.3 2.3 1 1 1 2 2 2 1 Sema domain TIG PF01833.24 KFP15397.1 - 1.3e-33 114.9 13.4 4.7e-11 42.6 1.8 5.2 5 0 0 5 5 5 4 IPT/TIG domain PSI PF01437.25 KFP15397.1 - 5.4e-15 55.7 48.6 1.5e-09 38.2 16.3 3.7 3 0 0 3 3 3 3 Plexin repeat TIG_plexin PF17960.1 KFP15397.1 - 1e-14 54.2 0.2 1e-14 54.2 0.2 3.6 4 0 0 4 4 4 1 TIG domain RasGAP PF00616.19 KFP15397.1 - 0.00016 21.4 0.0 0.0029 17.3 0.0 2.8 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase ubiquitin PF00240.23 KFP15397.1 - 0.063 13.0 0.3 1.4 8.7 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin family ARL2_Bind_BART PF11527.8 KFP15397.1 - 0.24 11.5 1.9 0.6 10.2 0.2 2.5 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Pkinase PF00069.25 KFP15398.1 - 8.5e-61 205.6 0.1 1e-60 205.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15398.1 - 1.9e-26 92.9 0.1 2.4e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP15398.1 - 6.3e-06 25.7 0.3 9.2e-06 25.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP15398.1 - 0.0012 18.8 0.0 0.014 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP15398.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KFP15399.1 - 8e-64 215.5 0.3 1.1e-63 215.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15399.1 - 1.4e-27 96.6 0.1 1.9e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP15399.1 - 9.5e-05 21.5 1.1 9.9e-05 21.4 0.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFP15399.1 - 0.00038 20.5 0.0 0.00086 19.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP15399.1 - 0.0036 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP15399.1 - 0.0045 16.3 0.0 0.007 15.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like UvrD_C PF13361.6 KFP15399.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3381 PF11861.8 KFP15399.1 - 0.03 14.1 1.7 0.12 12.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) FTA2 PF13095.6 KFP15399.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Fz PF01392.22 KFP15400.1 - 8.7e-27 93.9 5.1 8.7e-27 93.9 5.1 2.1 2 1 0 2 2 2 1 Fz domain GCP_C_terminal PF04130.13 KFP15401.1 - 8e-61 206.2 10.1 8e-61 206.2 10.1 2.0 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP15401.1 - 5.7e-38 131.3 0.1 1.2e-37 130.2 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4573 PF15140.6 KFP15401.1 - 2.6e-06 27.3 0.1 5.7e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) UPF0061 PF02696.14 KFP15402.1 - 2.5e-96 323.3 0.1 3.7e-96 322.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Metallopep PF12044.8 KFP15402.1 - 0.088 11.4 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family XPC-binding PF09280.11 KFP15402.1 - 0.22 11.3 3.6 0.18 11.6 1.0 2.2 2 0 0 2 2 2 0 XPC-binding domain TraB PF01963.17 KFP15403.1 - 9.9e-29 101.0 0.3 1.9e-28 100.1 0.1 1.5 2 0 0 2 2 2 1 TraB family DNA_pol_D_N PF18018.1 KFP15403.1 - 0.024 14.8 1.5 0.54 10.4 0.9 2.2 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Ribosomal_L22e PF01776.17 KFP15403.1 - 0.089 13.2 0.4 0.25 11.7 0.4 1.8 1 0 0 1 1 1 0 Ribosomal L22e protein family Innexin PF00876.18 KFP15404.1 - 6.5e-10 38.8 1.6 2.7e-09 36.8 1.4 1.9 1 1 1 2 2 2 1 Innexin DUF2207 PF09972.9 KFP15404.1 - 0.0049 15.7 0.1 0.0073 15.1 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Ecl1 PF12855.7 KFP15404.1 - 0.15 13.2 0.1 0.15 13.2 0.1 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins AAA_12 PF13087.6 KFP15406.1 - 1.1e-45 155.7 0.0 2.7e-45 154.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP15406.1 - 1.2e-32 113.7 0.0 1.2e-15 58.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain S1-like PF14444.6 KFP15406.1 - 1.5e-13 50.4 0.4 3.6e-05 23.6 0.8 3.6 3 0 0 3 3 3 3 S1-like AAA_30 PF13604.6 KFP15406.1 - 5.5e-13 49.1 0.0 1.3e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP15406.1 - 2.3e-07 31.2 0.0 7e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFP15406.1 - 0.00044 20.3 0.0 0.00098 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP15406.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase FLgD_tudor PF13861.6 KFP15406.1 - 0.0028 17.8 0.0 3.3 8.0 0.0 2.7 2 0 0 2 2 2 2 FlgD Tudor-like domain UvrD_C_2 PF13538.6 KFP15406.1 - 0.007 16.2 0.7 0.12 12.2 0.3 3.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KFP15406.1 - 0.098 12.9 0.0 0.31 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KFP15406.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KFP15406.1 - 0.11 12.0 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KFP15406.1 - 0.18 11.7 0.0 0.92 9.3 0.0 2.1 2 0 0 2 2 2 0 Helicase UvrD_C PF13361.6 KFP15406.1 - 0.19 11.0 0.0 33 3.7 0.0 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain KASH PF10541.9 KFP15407.1 - 1.9 8.8 7.0 6 7.2 0.1 2.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain IL17_R_N PF15037.6 KFP15409.1 - 3.8e-34 118.3 10.0 2.1e-33 115.9 9.9 1.9 1 1 0 1 1 1 1 Interleukin-17 receptor extracellular region Pkinase PF00069.25 KFP15416.1 - 1.3e-36 126.3 0.0 2.4e-33 115.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15416.1 - 6.2e-10 38.8 0.0 2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP15416.1 - 0.0022 17.3 0.0 0.0036 16.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like zf-ZPR1 PF03367.13 KFP15416.1 - 0.16 11.8 0.1 12 5.7 0.0 2.1 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DUF4207 PF13904.6 KFP15417.1 - 4.6e-31 108.4 34.5 5.6e-31 108.1 34.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Ndc1_Nup PF09531.10 KFP15417.1 - 1.2 7.7 6.1 1.2 7.7 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ponericin PF07442.11 KFP15417.1 - 9.2 6.4 13.4 13 5.9 2.8 3.3 3 0 0 3 3 3 0 Ponericin TauD PF02668.16 KFP15418.1 - 1e-40 140.3 0.1 1.6e-40 139.6 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFP15418.1 - 4.8e-22 78.4 2.5 2.7e-17 63.2 0.3 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.10 KFP15418.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF2442 PF10387.9 KFP15418.1 - 0.052 13.8 0.0 4.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Raf1_N PF18578.1 KFP15418.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain GARS_A PF01071.19 KFP15418.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SSF PF00474.17 KFP15419.1 - 4.8e-38 131.1 21.3 6e-38 130.8 21.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.9 KFP15419.1 - 0.35 10.9 5.1 0.1 12.6 0.6 2.5 3 1 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Anoctamin PF04547.12 KFP15420.1 - 7.1e-158 526.1 16.1 8.8e-158 525.8 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP15420.1 - 2.1e-76 256.6 1.8 3.7e-76 255.8 1.8 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2559 PF10832.8 KFP15421.1 - 0.097 12.8 0.3 0.097 12.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2559) CALCOCO1 PF07888.11 KFP15421.1 - 0.2 10.5 32.8 0.32 9.8 32.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 KFP15421.1 - 0.24 10.9 33.1 0.027 14.0 9.0 2.0 1 1 1 2 2 2 0 Leucine zipper CmlA_N PF18456.1 KFP15421.1 - 0.33 10.2 9.0 0.1 11.9 1.4 2.2 1 1 1 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain DUF3584 PF12128.8 KFP15421.1 - 0.68 7.4 27.0 0.98 6.9 27.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.13 KFP15421.1 - 0.94 7.8 32.8 1.1 7.6 32.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein WEMBL PF05701.11 KFP15421.1 - 1.1 7.9 30.3 58 2.2 30.7 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light EzrA PF06160.12 KFP15421.1 - 1.5 6.9 27.0 0.076 11.2 2.9 3.0 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Cep57_CLD_2 PF14197.6 KFP15421.1 - 1.9 8.6 32.2 4.1 7.6 7.9 3.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 YkyA PF10368.9 KFP15421.1 - 2.1 8.0 34.4 0.11 12.2 19.6 2.4 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF1612 PF07756.12 KFP15421.1 - 2.2 8.5 7.7 39 4.5 2.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1612) TPR_MLP1_2 PF07926.12 KFP15421.1 - 2.5 8.2 37.0 0.092 12.8 21.2 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 KFP15421.1 - 2.8 7.4 31.0 8 5.9 4.5 2.9 1 1 2 3 3 3 0 Intermediate filament protein V_ATPase_I PF01496.19 KFP15421.1 - 3.5 5.4 19.0 0.51 8.2 14.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KFP15421.1 - 6.9 5.5 35.0 2.4 7.0 25.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DHR10 PF18595.1 KFP15421.1 - 7.1 6.7 37.7 1.8 8.6 20.9 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain TMEM192 PF14802.6 KFP15421.1 - 7.3 5.6 9.3 53 2.8 9.3 2.0 1 1 0 1 1 1 0 TMEM192 family YfcL PF08891.11 KFP15421.1 - 7.4 7.0 9.0 15 6.0 1.9 2.9 2 1 0 2 2 2 0 YfcL protein Fib_alpha PF08702.10 KFP15421.1 - 7.4 6.8 22.8 1.2 9.3 13.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KFP15421.1 - 8.2 7.1 26.4 2.5 8.8 7.7 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF4047 PF13256.6 KFP15421.1 - 9.2 6.5 14.2 3.7 7.7 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) Ras PF00071.22 KFP15422.1 - 2.4e-48 163.8 0.0 2.8e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15422.1 - 2e-27 95.8 0.0 2.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP15422.1 - 3e-14 52.8 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP15422.1 - 8.5e-06 25.3 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP15422.1 - 1.4e-05 25.2 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP15422.1 - 2.2e-05 24.1 0.0 0.0027 17.3 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP15422.1 - 2.4e-05 23.8 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CENP-M PF11111.8 KFP15422.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) CAP PF00188.26 KFP15423.1 - 1e-20 74.8 0.4 1.8e-20 74.0 0.4 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mito_carr PF00153.27 KFP15424.1 - 1.2e-13 50.7 0.2 1.3e-08 34.7 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein RabGAP-TBC PF00566.18 KFP15425.1 - 9.4e-53 179.0 2.9 1.3e-52 178.6 2.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4864 PF16156.5 KFP15425.1 - 0.092 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) EPL1 PF10513.9 KFP15426.1 - 1.4e-37 129.5 0.3 1.3e-35 123.1 0.4 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 KFP15426.1 - 1.3e-36 125.1 6.3 1.3e-36 125.1 6.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP15426.1 - 2.4e-25 88.6 4.1 2.4e-25 88.6 4.1 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KFP15426.1 - 2.6e-20 72.3 0.2 7.5e-20 70.8 0.2 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.17 KFP15426.1 - 2.1e-17 63.3 0.0 7.9e-17 61.5 0.0 2.1 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 KFP15426.1 - 4e-12 45.5 6.8 4e-12 45.5 6.8 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KFP15426.1 - 2.4e-06 27.3 28.6 0.00011 22.1 16.8 2.8 2 0 0 2 2 2 2 PHD-finger Elf-1_N PF12310.8 KFP15426.1 - 0.058 13.9 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Transcription factor protein N terminal C1_1 PF00130.22 KFP15426.1 - 2 8.4 19.2 0.041 13.8 6.5 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFP15427.1 - 1.8e-65 220.9 0.2 2.1e-65 220.7 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15427.1 - 6e-27 94.5 0.1 8.9e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP15427.1 - 4.8e-05 23.4 0.1 9.1e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP15427.1 - 0.00014 21.3 0.2 0.0002 20.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP15427.1 - 0.0042 16.5 0.2 0.015 14.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP15427.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3754 PF12576.8 KFP15427.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) FTA2 PF13095.6 KFP15427.1 - 0.085 12.5 0.3 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KFP15428.1 - 3.9e-59 200.2 0.1 4.6e-59 199.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15428.1 - 7e-28 97.6 0.0 9.4e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP15428.1 - 6.6e-05 22.4 0.4 0.0001 21.7 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP15428.1 - 0.0067 16.4 0.4 0.031 14.2 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP15428.1 - 0.039 12.9 0.4 0.059 12.3 0.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFP15428.1 - 0.059 12.7 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Sulfate_transp PF00916.20 KFP15429.1 - 1.1e-72 244.9 25.9 1.1e-72 244.9 25.9 1.5 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KFP15429.1 - 1.1e-20 73.4 0.0 6.7e-20 70.9 0.0 2.1 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFP15429.1 - 7.9e-06 26.2 13.5 2.6e-05 24.6 3.4 3.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily PRIMA1 PF16101.5 KFP15429.1 - 0.013 15.6 0.2 0.039 14.0 0.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 KFP15430.1 - 2e-41 142.1 3.7 4.3e-21 75.5 0.0 3.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15430.1 - 3e-13 49.7 1.3 2.5e-09 36.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP15430.1 - 0.06 12.1 0.1 0.06 12.1 0.1 2.0 1 1 0 2 2 2 0 Fungal protein kinase NARP1 PF12569.8 KFP15430.1 - 3 6.6 9.1 5.6 5.8 9.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FKBP_C PF00254.28 KFP15431.1 - 3.3e-46 155.5 0.1 3.4e-28 97.8 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFP15431.1 - 1.4e-15 56.4 13.1 1.5e-08 34.1 1.9 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP15431.1 - 2.5e-11 42.8 8.5 2.8e-05 23.9 1.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP15431.1 - 4.3e-11 42.1 5.8 2.6e-05 24.1 0.7 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP15431.1 - 5.3e-07 29.8 1.9 0.00057 20.1 1.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP15431.1 - 3.4e-06 27.4 0.9 0.0015 19.0 0.7 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP15431.1 - 4.7e-06 26.2 0.7 3.1e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP15431.1 - 8.5e-06 26.1 2.6 0.045 14.4 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP15431.1 - 8.6e-05 22.1 2.2 0.047 13.4 0.1 3.3 2 1 1 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 KFP15431.1 - 0.0001 22.3 2.2 0.012 15.6 0.2 2.6 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KFP15431.1 - 0.0002 21.4 0.3 0.0013 18.8 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KFP15431.1 - 0.0035 17.4 0.0 0.035 14.2 0.0 2.7 3 1 0 3 3 3 1 BDBT FKBP like N-terminal DUF3856 PF12968.7 KFP15431.1 - 0.0054 16.8 0.3 0.0098 16.0 0.3 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 KFP15431.1 - 0.011 16.4 0.1 0.16 12.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 KFP15431.1 - 0.029 13.1 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 KFP15431.1 - 0.13 12.5 6.3 0.32 11.2 1.7 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP15431.1 - 0.55 10.7 3.3 46 4.7 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat YBD PF17725.1 KFP15432.1 - 1.1e-94 316.2 0.5 1.4e-94 315.8 0.5 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFP15432.1 - 5e-24 84.1 0.0 1.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Rotamase_2 PF13145.6 KFP15432.1 - 0.13 13.1 0.0 0.25 12.2 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain FA_FANCE PF11510.8 KFP15434.1 - 4.5e-60 203.2 10.2 7.1e-60 202.6 10.2 1.3 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE zf-C4 PF00105.18 KFP15435.1 - 4.9e-09 36.5 5.0 7.5e-09 35.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C2H2 PF00096.26 KFP15436.1 - 6.1e-08 32.7 10.5 0.00031 21.0 2.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15436.1 - 0.00018 22.1 10.3 0.1 13.5 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger NOA36 PF06524.12 KFP15436.1 - 0.01 15.2 0.6 0.012 15.0 0.6 1.1 1 0 0 1 1 1 0 NOA36 protein FOXP-CC PF16159.5 KFP15436.1 - 0.034 14.8 4.4 0.1 13.3 0.8 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFP15436.1 - 0.039 14.0 7.8 0.26 11.4 1.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FYDLN_acid PF09538.10 KFP15436.1 - 0.12 13.0 6.6 0.4 11.4 6.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 KFP15436.1 - 0.18 11.9 4.2 0.12 12.5 2.4 1.8 1 1 0 1 1 1 0 CpXC protein zf-C2H2_aberr PF17017.5 KFP15436.1 - 0.52 10.4 5.7 0.29 11.3 2.6 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KFP15436.1 - 0.54 10.8 17.8 1.2 9.7 7.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_2 PF13465.6 KFP15437.1 - 2.7e-29 100.3 20.2 3.8e-10 39.7 1.0 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP15437.1 - 2.8e-22 77.9 16.1 1.5e-07 31.4 0.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15437.1 - 1.1e-16 60.1 14.1 0.00014 22.4 0.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP15437.1 - 1.4e-09 38.0 0.6 0.011 16.0 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP15437.1 - 7.3e-06 26.2 5.1 0.22 11.7 0.3 3.6 1 1 2 3 3 3 3 Aberrant zinc-finger zf-TRAF PF02176.18 KFP15437.1 - 0.00011 22.8 1.0 0.00011 22.8 1.0 2.4 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C2H2_6 PF13912.6 KFP15437.1 - 0.00046 20.1 11.2 0.038 14.0 0.2 4.1 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP15437.1 - 0.0032 17.7 2.8 0.048 14.0 0.2 2.3 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KFP15437.1 - 0.0039 17.5 5.9 3.4 8.2 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFP15437.1 - 0.019 15.6 2.0 23 5.7 0.0 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 KFP15437.1 - 0.033 14.2 6.0 0.46 10.5 0.9 3.4 2 1 2 4 4 4 0 Ogr/Delta-like zinc finger zf_ZIC PF18366.1 KFP15437.1 - 0.038 14.1 3.8 9 6.5 0.1 3.7 2 2 2 4 4 4 0 Zic proteins zinc finger domain zf-DNA_Pol PF08996.10 KFP15437.1 - 0.059 13.1 2.2 3.4 7.4 0.2 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DUF3268 PF11672.8 KFP15437.1 - 0.14 12.5 2.4 0.28 11.5 0.2 2.0 2 0 0 2 2 2 0 zinc-finger-containing domain zf-UBP PF02148.19 KFP15437.1 - 0.28 11.6 6.2 1.9 8.9 0.1 3.2 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein IBR PF01485.21 KFP15437.1 - 0.36 11.1 8.6 1.1 9.5 0.9 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain Ribosomal_L1 PF00687.21 KFP15438.1 - 3.7e-45 154.2 5.5 4.5e-45 153.9 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 KFP15438.1 - 0.061 13.4 3.0 0.13 12.4 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function TetR PF13972.6 KFP15438.1 - 0.069 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor PID PF00640.23 KFP15439.1 - 1.9e-19 70.1 0.9 4.2e-19 69.0 0.9 1.6 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP15439.1 - 0.00038 20.6 0.0 0.00056 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP15439.1 - 0.0034 17.3 0.1 0.0042 17.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.13 KFP15439.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TAFII28 PF04719.14 KFP15440.1 - 1.6e-39 133.8 0.0 2.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KFP15440.1 - 2.7e-06 27.5 0.0 5.8e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.10 KFP15440.1 - 0.031 14.6 1.6 8.7 6.7 0.4 2.7 3 0 0 3 3 3 0 CENP-S associating Centromere protein X zf-U1 PF06220.12 KFP15441.1 - 4.1e-22 77.6 6.8 5.5e-22 77.2 6.8 1.2 1 0 0 1 1 1 1 U1 zinc finger Phage_int_SAM_3 PF14659.6 KFP15441.1 - 0.13 12.6 0.1 0.71 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-C2H2_jaz PF12171.8 KFP15441.1 - 2.2 8.6 9.9 26 5.3 9.9 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP15441.1 - 2.6 8.6 5.1 25 5.4 5.1 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type N_BRCA1_IG PF16158.5 KFP15442.1 - 3.9e-34 117.4 0.2 7e-34 116.6 0.2 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene CARDB PF07705.11 KFP15442.1 - 0.067 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 CARDB FCH PF00611.23 KFP15443.1 - 7.8e-17 61.3 0.3 7.8e-17 61.3 0.3 2.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFP15443.1 - 2.8e-15 55.9 0.4 6e-15 54.8 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP15443.1 - 1e-14 53.8 0.1 2e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP15443.1 - 2.4e-07 30.3 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain KAP_NTPase PF07693.14 KFP15443.1 - 0.0099 15.1 1.1 0.013 14.8 1.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain PilJ PF13675.6 KFP15443.1 - 0.33 11.0 4.4 0.36 10.9 0.1 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PAP_central PF04928.17 KFP15443.1 - 0.43 9.5 3.9 0.94 8.4 3.9 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain Laminin_II PF06009.12 KFP15443.1 - 0.59 10.2 6.8 0.35 10.9 3.7 2.1 2 0 0 2 2 2 0 Laminin Domain II Tho2 PF11262.8 KFP15443.1 - 3.3 6.8 17.1 0.9 8.7 11.5 2.3 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 OmpH PF03938.14 KFP15443.1 - 7.3 6.9 26.0 0.24 11.8 17.3 2.6 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KFP15443.1 - 8.1 6.5 25.9 17 5.5 0.4 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein NUDIX PF00293.28 KFP15445.1 - 5.8e-16 58.7 0.3 6.7e-16 58.5 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain 7tm_1 PF00001.21 KFP15446.1 - 3e-46 157.9 12.5 4.2e-46 157.4 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.9 KFP15446.1 - 1.1e-25 89.2 3.3 2.5e-25 88.0 3.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.9 KFP15446.1 - 8.7e-14 51.5 15.4 6.2e-13 48.7 15.4 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFP15446.1 - 2.7e-08 33.5 12.5 2.7e-08 33.5 12.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP15446.1 - 2.2e-07 30.5 16.3 3.2e-07 30.0 16.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.13 KFP15446.1 - 5.1e-05 22.5 7.8 0.00069 18.8 1.0 2.2 2 0 0 2 2 2 2 Taste receptor protein (TAS2R) 7tm_4 PF13853.6 KFP15446.1 - 0.00016 21.5 12.4 0.00078 19.3 12.4 1.9 1 1 0 1 1 1 1 Olfactory receptor DUF4079 PF13301.6 KFP15446.1 - 0.0083 16.3 4.5 0.19 11.8 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) FA_desaturase PF00487.24 KFP15446.1 - 1.8 8.3 13.0 0.14 11.9 0.4 2.3 2 1 0 2 2 2 0 Fatty acid desaturase 60KD_IMP PF02096.20 KFP15446.1 - 4.5 7.2 9.0 27 4.6 8.5 2.5 1 1 0 1 1 1 0 60Kd inner membrane protein MSC PF09402.10 KFP15447.1 - 5.9e-21 75.3 0.2 7.5e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain TssO PF17561.2 KFP15447.1 - 0.23 11.5 1.8 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO Bcl-2 PF00452.19 KFP15448.1 - 1.2e-26 93.3 0.0 1.2e-26 93.3 0.0 1.8 3 0 0 3 3 3 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.6 KFP15448.1 - 0.0032 18.1 0.1 0.061 14.0 0.0 2.1 2 0 0 2 2 2 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like DUF4051 PF13260.6 KFP15448.1 - 1.4 8.7 5.8 1.4 8.7 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Macro PF01661.21 KFP15449.1 - 5.4e-08 32.9 0.0 8.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Macro domain PSII_Pbs27 PF13326.6 KFP15449.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.5 1 1 1 2 2 2 0 Photosystem II Pbs27 CBFB_NFYA PF02045.15 KFP15450.1 - 2e-27 95.6 8.7 3.2e-27 94.9 8.7 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B V-set PF07686.17 KFP15451.1 - 2e-10 40.8 1.6 2.9e-10 40.3 1.6 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Egh16-like PF11327.8 KFP15451.1 - 0.026 15.0 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Egh16-like virulence factor Herpes_gE PF02480.16 KFP15451.1 - 0.028 13.2 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ig PF00047.25 KFP15451.1 - 0.038 14.1 0.3 0.089 13.0 0.3 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KFP15451.1 - 0.044 14.4 1.0 0.14 12.8 1.0 1.9 1 1 0 1 1 1 0 Immunoglobulin domain SIT PF15330.6 KFP15452.1 - 0.00071 20.0 0.1 0.0011 19.4 0.1 1.3 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT ECSCR PF15820.5 KFP15452.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.4 1 1 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Cadherin_C_2 PF16492.5 KFP15452.1 - 0.008 16.9 0.0 0.015 16.0 0.0 1.6 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 KFP15452.1 - 0.012 15.5 0.1 0.024 14.5 0.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family Vpu PF00558.19 KFP15452.1 - 0.019 14.7 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.6 KFP15452.1 - 0.089 13.7 0.1 0.13 13.2 0.1 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 KFP15452.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SKG6 PF08693.10 KFP15452.1 - 0.24 10.8 2.2 0.46 9.9 2.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FOXP-CC PF16159.5 KFP15453.1 - 1.9e-34 118.1 5.0 1.9e-34 118.1 5.0 2.2 2 0 0 2 2 2 1 FOXP coiled-coil domain Forkhead PF00250.18 KFP15453.1 - 8.4e-28 96.5 0.1 8.4e-28 96.5 0.1 1.7 2 0 0 2 2 2 1 Forkhead domain Zap1_zf2 PF18217.1 KFP15453.1 - 0.027 14.5 0.5 0.053 13.5 0.5 1.5 1 0 0 1 1 1 0 Zap1 zinc finger 2 Bestrophin PF01062.21 KFP15453.1 - 0.14 11.5 1.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel CCDC24 PF15669.5 KFP15453.1 - 8.8 6.1 9.3 0.86 9.4 1.0 3.0 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 24 family MDFI PF15316.6 KFP15454.1 - 5.5e-46 156.8 50.6 6.4e-46 156.5 50.6 1.0 1 0 0 1 1 1 1 MyoD family inhibitor Asp PF00026.23 KFP15455.1 - 2e-85 287.0 0.0 3.7e-85 286.1 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.12 KFP15455.1 - 1.1e-11 44.3 3.2 2.1e-11 43.5 3.2 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_N PF14543.6 KFP15455.1 - 2.9e-11 43.9 0.1 4.7e-10 40.0 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFP15455.1 - 0.00082 19.2 0.0 0.0032 17.3 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.12 KFP15456.1 - 8.2e-11 41.6 0.6 1.2e-10 41.0 0.6 1.3 1 0 0 1 1 1 1 A1 Propeptide Asp PF00026.23 KFP15456.1 - 3.6e-09 36.5 0.1 4.7e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP15456.1 - 0.00024 21.4 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal IRS PF02174.17 KFP15457.1 - 1.3e-26 92.4 0.0 2.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Notch PF00066.17 KFP15457.1 - 0.025 15.0 8.2 0.08 13.4 8.2 1.9 1 0 0 1 1 1 0 LNR domain UCH PF00443.29 KFP15458.1 - 1.2e-57 195.4 0.2 1.2e-57 195.4 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP15458.1 - 3e-21 75.5 7.1 3e-21 75.5 7.1 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFP15458.1 - 2e-16 60.5 0.2 2e-16 60.5 0.2 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KFP15458.1 - 0.038 13.7 0.4 0.038 13.7 0.4 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger Stc1 PF12898.7 KFP15458.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.0 3 0 0 3 3 3 0 Stc1 domain ArfGap PF01412.18 KFP15458.1 - 6.6 6.8 9.6 0.36 10.9 2.5 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Med20 PF08612.11 KFP15459.1 - 2.6e-37 128.4 0.0 2.9e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Bystin PF05291.11 KFP15460.1 - 9.4e-136 451.8 0.7 1.1e-135 451.6 0.7 1.0 1 0 0 1 1 1 1 Bystin Cyclin_N PF00134.23 KFP15461.1 - 5.9e-28 97.2 0.3 1.2e-27 96.1 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP15461.1 - 1e-19 70.7 0.8 3e-19 69.3 0.2 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.10 KFP15461.1 - 0.00014 22.2 0.4 0.00024 21.5 0.4 1.3 1 0 0 1 1 1 1 K cyclin, C terminal Herp-Cyclin PF09241.10 KFP15461.1 - 0.025 15.2 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 Herpesviridae viral cyclin Bromo_TP PF07524.13 KFP15462.1 - 1.3e-30 105.2 0.7 3.3e-30 103.9 0.2 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 KFP15462.1 - 1.2e-22 80.2 1.3 3.2e-22 78.8 1.3 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 KFP15462.1 - 2.8e-05 24.2 0.0 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP_like PF17027.5 KFP15462.1 - 0.00027 21.1 0.0 0.00053 20.1 0.0 1.5 1 0 0 1 1 1 1 Histone-fold protein DUF3090 PF11290.8 KFP15462.1 - 0.0053 16.6 0.4 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3090) CENP-S PF15630.6 KFP15462.1 - 0.018 15.4 0.0 0.05 14.0 0.0 1.8 1 1 0 1 1 1 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP15462.1 - 0.048 13.9 0.1 0.095 13.0 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFP15462.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Type2_restr_D3 PF16902.5 KFP15462.1 - 0.098 12.6 0.2 57 3.7 0.1 3.6 4 0 0 4 4 4 0 Type-2 restriction enzyme D3 domain SHIPPO-rpt PF07004.12 KFP15463.1 - 0.0098 16.8 9.9 0.087 13.8 0.1 4.1 3 2 0 3 3 3 2 Sperm-tail PG-rich repeat ECR1_N PF14382.6 KFP15463.1 - 0.036 13.9 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Glyco_hydro_18 PF00704.28 KFP15464.1 - 6e-92 308.7 2.0 7.2e-92 308.4 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KFP15464.1 - 6.4e-09 35.9 7.8 1.2e-08 34.9 7.8 1.5 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain BTG PF07742.12 KFP15465.1 - 2.7e-34 117.5 0.0 3.3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 BTG family LRR_8 PF13855.6 KFP15466.1 - 9e-32 108.6 25.0 2e-10 40.3 0.2 6.3 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP15466.1 - 9e-24 83.2 26.9 6.9e-07 29.5 0.6 7.0 2 2 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP15466.1 - 1.2e-10 41.2 5.1 7.5e-05 22.3 0.1 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFP15466.1 - 4.9e-10 38.5 21.5 0.2 12.4 0.1 9.6 9 2 1 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP15466.1 - 6.5e-09 35.1 17.2 0.2 11.8 0.0 8.5 10 0 0 10 10 10 4 Leucine Rich repeat LRRNT PF01462.18 KFP15466.1 - 3.1e-07 29.9 4.2 7.9e-07 28.6 2.0 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 KFP15466.1 - 4.7e-07 29.8 2.9 4.8e-05 23.3 0.0 2.8 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 KFP15466.1 - 4.6e-06 26.7 0.0 0.16 12.2 0.0 4.5 2 2 3 5 5 5 2 FNIP Repeat Cation_ATPase_C PF00689.21 KFP15467.1 - 1.8e-44 151.6 4.1 5.7e-44 150.0 1.4 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.8 KFP15467.1 - 3.5e-27 94.6 0.1 1.2e-26 92.9 0.1 2.0 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal E1-E2_ATPase PF00122.20 KFP15467.1 - 2.1e-26 92.5 9.2 8.9e-17 61.2 0.1 2.8 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 KFP15467.1 - 2.3e-20 72.4 0.0 4.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFP15467.1 - 2.1e-15 56.2 0.0 8.1e-15 54.3 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFP15467.1 - 8e-13 49.2 1.8 2.9e-11 44.0 1.8 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP15467.1 - 5.2e-05 23.1 0.0 0.0046 16.7 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 KFP15467.1 - 4.5 7.2 5.7 26 4.7 0.0 2.7 2 1 0 2 2 2 0 Ferlin C-terminus LSM PF01423.22 KFP15468.1 - 4.2e-18 64.8 0.3 4.5e-18 64.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFP15468.1 - 0.0078 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Choline_kinase PF01633.20 KFP15469.1 - 1.1e-59 201.6 0.0 1.6e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFP15469.1 - 1.4e-12 48.1 0.1 1.8e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP15469.1 - 0.00041 19.8 0.7 0.0013 18.2 0.7 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Tsi6 PF18660.1 KFP15469.1 - 0.18 11.9 0.2 2.9 8.0 0.1 2.7 2 1 1 3 3 3 0 Tsi6 Got1 PF04178.12 KFP15470.1 - 3.8e-17 62.7 16.8 4.4e-17 62.5 16.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PP1c_bdg PF10488.9 KFP15471.1 - 6e-127 423.0 11.3 6.8e-127 422.8 11.3 1.0 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region DCA16 PF15349.6 KFP15471.1 - 0.11 12.0 6.2 0.18 11.3 6.2 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 SDA1 PF05285.12 KFP15471.1 - 0.13 11.6 9.1 0.17 11.3 9.1 1.3 1 0 0 1 1 1 0 SDA1 HIGH_NTase1_ass PF16581.5 KFP15471.1 - 0.19 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region VEFS-Box PF09733.9 KFP15471.1 - 0.23 11.3 8.2 1 9.2 1.5 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein R3H-assoc PF13902.6 KFP15471.1 - 0.68 10.3 4.7 7.1 7.0 2.4 2.4 1 1 1 2 2 2 0 R3H-associated N-terminal domain DUF4099 PF13351.6 KFP15472.1 - 0.036 14.3 0.1 0.039 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) zf-C3HC4_3 PF13920.6 KFP15473.1 - 6.7e-11 41.9 6.5 6.7e-11 41.9 6.5 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFP15473.1 - 3.8e-06 26.7 0.0 7.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-RanBP PF00641.18 KFP15473.1 - 7.3e-06 25.2 8.6 7.3e-06 25.2 8.6 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 KFP15473.1 - 0.14 12.2 16.0 1.4 9.0 2.4 3.0 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFP15473.1 - 9.7 6.1 15.8 4.2 7.2 1.5 3.1 2 0 0 2 2 2 0 zinc-ribbon domain LRR_8 PF13855.6 KFP15474.1 - 5.8e-65 214.9 87.4 2e-14 53.1 6.1 6.6 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 KFP15474.1 - 1.1e-23 82.9 44.6 0.00048 20.5 2.6 7.9 2 1 7 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP15474.1 - 7.7e-18 64.7 0.0 1.1e-08 35.1 0.0 2.9 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP15474.1 - 2.1e-14 53.4 18.1 0.0001 21.9 2.1 4.6 1 1 4 5 5 5 5 Leucine-rich repeat I-set PF07679.16 KFP15474.1 - 3.1e-14 52.8 0.0 5.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP15474.1 - 3.7e-11 43.4 0.0 7.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP15474.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP15474.1 - 9.8e-06 25.4 29.9 0.2 12.3 0.1 10.2 10 1 0 10 10 9 2 Leucine Rich Repeat ig PF00047.25 KFP15474.1 - 8.2e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP15474.1 - 0.00091 19.4 0.0 0.0071 16.5 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRRCT PF01463.24 KFP15474.1 - 0.045 14.3 0.2 0.26 11.9 0.2 2.5 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRRNT PF01462.18 KFP15474.1 - 1.4 8.6 7.5 0.15 11.8 1.7 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LSM PF01423.22 KFP15475.1 - 5.2e-09 35.7 0.1 1.1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 LSM domain DDHD PF02862.17 KFP15476.1 - 2.2e-50 171.9 0.0 4.6e-50 170.8 0.0 1.6 1 0 0 1 1 1 1 DDHD domain SAM_1 PF00536.30 KFP15476.1 - 2.2e-13 50.4 0.1 4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.20 KFP15476.1 - 1e-05 26.0 1.9 0.0015 19.0 0.5 2.8 2 0 0 2 2 2 1 WWE domain SAM_2 PF07647.17 KFP15476.1 - 2.4e-05 24.3 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KFP15476.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 IGR protein motif DUF676 PF05057.14 KFP15476.1 - 0.15 11.5 0.5 7.2 6.1 0.1 2.6 2 1 0 2 2 2 0 Putative serine esterase (DUF676) HABP4_PAI-RBP1 PF04774.15 KFP15476.1 - 0.94 10.3 4.5 8.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family PAP2 PF01569.21 KFP15477.1 - 5.6e-31 107.1 1.4 5.6e-31 107.1 1.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KFP15477.1 - 0.016 14.9 5.4 0.54 9.9 5.4 2.5 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.6 KFP15477.1 - 0.023 15.2 0.3 0.057 14.0 0.3 1.6 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Virul_fac_BrkB PF03631.15 KFP15477.1 - 0.14 11.7 2.2 9.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB RseC_MucC PF04246.12 KFP15477.1 - 0.16 11.9 2.0 10 6.1 0.2 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4231 PF14015.6 KFP15477.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) YhhN PF07947.14 KFP15477.1 - 0.31 10.6 5.6 4.7 6.8 5.7 2.6 1 1 0 1 1 1 0 YhhN family DUF5389 PF17364.2 KFP15477.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5389) C5HCH PF17982.1 KFP15478.1 - 3.8e-24 84.6 13.0 3.8e-24 84.6 13.0 5.1 4 1 0 4 4 4 1 NSD Cys-His rich domain SET PF00856.28 KFP15478.1 - 3.3e-21 76.4 0.7 4.5e-20 72.7 0.4 2.9 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KFP15478.1 - 3.3e-17 62.2 8.5 3.3e-17 62.2 8.5 5.1 5 0 0 5 5 5 1 AWS domain PWWP PF00855.17 KFP15478.1 - 9.6e-16 58.0 0.1 9.6e-16 58.0 0.1 2.0 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 KFP15478.1 - 6.6e-12 45.1 74.6 5.1e-05 23.1 12.9 6.7 4 2 2 6 6 6 4 PHD-finger zf-HC5HC2H_2 PF13832.6 KFP15478.1 - 0.00013 22.1 3.3 0.00013 22.1 3.3 6.3 3 2 4 7 7 7 3 PHD-zinc-finger like domain AA_permease_2 PF13520.6 KFP15480.1 - 1.3e-50 172.5 29.4 1.7e-50 172.1 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP15480.1 - 8.8e-17 60.8 30.2 1e-15 57.3 30.2 2.1 1 1 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.6 KFP15481.1 - 1.3e-08 34.4 0.0 3.6e-06 26.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP15481.1 - 0.00055 19.2 0.0 0.018 14.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Nbs1_C PF08599.10 KFP15482.1 - 2.8e-34 117.1 0.3 1.2e-33 115.0 0.3 2.2 1 0 0 1 1 1 1 DNA damage repair protein Nbs1 NIBRIN_BRCT_II PF16508.5 KFP15482.1 - 1.4e-29 102.9 0.0 1.3e-28 99.7 0.0 2.7 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KFP15482.1 - 5.7e-15 55.4 0.2 1.5e-14 54.1 0.2 1.8 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 KFP15482.1 - 4.2e-10 39.9 0.4 3.5e-08 33.7 0.1 3.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KFP15482.1 - 7.4e-07 29.0 0.3 3.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 KFP15482.1 - 1.8e-05 25.0 0.0 0.00014 22.1 0.0 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PTCB-BRCT PF12738.7 KFP15482.1 - 0.00013 21.9 0.1 0.00026 20.9 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFP15482.1 - 0.069 13.6 0.0 2.8 8.4 0.0 2.9 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain MU2_FHA PF18221.1 KFP15482.1 - 0.15 12.1 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 Mutator 2 Fork head associated domain adh_short_C2 PF13561.6 KFP15483.1 - 1.2e-48 165.8 0.5 1.7e-48 165.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP15483.1 - 6.9e-35 120.3 2.1 9.9e-35 119.8 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP15483.1 - 1.5e-07 31.5 0.3 2.4e-07 30.9 0.3 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFP15483.1 - 0.008 15.6 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFP15483.1 - 0.013 14.5 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EF-hand_1 PF00036.32 KFP15485.1 - 2.3e-24 83.1 10.6 1.4e-07 30.6 1.0 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFP15485.1 - 3e-23 79.7 10.2 8.9e-08 31.5 0.6 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KFP15485.1 - 4.2e-21 75.2 7.7 7.1e-11 42.4 2.2 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP15485.1 - 7.1e-15 53.7 8.8 0.00035 19.9 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP15485.1 - 8.9e-10 38.3 2.6 1.6e-06 27.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair T3SS_HrpK1 PF16937.5 KFP15485.1 - 0.00077 19.2 0.2 0.11 12.1 0.0 2.4 2 1 1 3 3 3 1 Type III secretion system translocator protein, HrpF SPARC_Ca_bdg PF10591.9 KFP15485.1 - 0.006 16.9 4.5 1.1 9.6 0.1 3.4 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region LXG PF04740.12 KFP15485.1 - 0.022 14.5 3.8 2.1 8.0 0.2 3.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily Caleosin PF05042.13 KFP15485.1 - 0.025 14.5 2.0 2.8 7.9 0.1 3.2 1 1 3 4 4 4 0 Caleosin related protein Styelin PF17562.2 KFP15485.1 - 0.082 13.3 0.1 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 Styelin EF-hand_10 PF14788.6 KFP15485.1 - 0.12 12.3 9.8 2.5 8.0 0.3 4.3 3 1 1 4 4 4 0 EF hand ArgoMid PF16487.5 KFP15485.1 - 0.13 12.6 0.4 3.6 7.9 0.0 3.0 3 1 0 3 3 3 0 Mid domain of argonaute Phage_DsbA PF11126.8 KFP15485.1 - 0.14 12.4 4.7 15 5.9 0.1 3.3 2 1 1 3 3 3 0 Transcriptional regulator DsbA EF-hand_9 PF14658.6 KFP15485.1 - 0.14 12.5 0.2 27 5.2 0.0 3.2 3 1 1 4 4 3 0 EF-hand domain Dockerin_1 PF00404.18 KFP15485.1 - 0.22 11.7 2.7 1.9 8.8 0.1 3.1 2 2 2 4 4 4 0 Dockerin type I domain ABM PF03992.16 KFP15488.1 - 9.9e-11 41.6 0.1 2e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_1 PF00036.32 KFP15488.1 - 3.2e-05 23.1 1.7 0.43 10.2 0.0 3.4 2 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP15488.1 - 0.00012 21.8 0.6 0.15 12.1 0.1 3.5 2 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFP15488.1 - 0.00012 22.4 3.3 0.016 15.7 0.9 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP15488.1 - 0.0037 17.1 1.2 0.073 12.9 1.2 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP15488.1 - 0.021 14.3 0.3 1.5 8.4 0.0 2.9 1 1 1 2 2 2 0 EF hand MRP-L28 PF09812.9 KFP15488.1 - 0.077 13.1 0.7 0.077 13.1 0.7 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L28 zf-C4H2 PF10146.9 KFP15488.1 - 0.15 12.4 5.2 0.65 10.3 0.7 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Exonuc_VII_S PF02609.16 KFP15488.1 - 0.25 11.4 7.6 0.9 9.6 0.1 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit EF-hand_10 PF14788.6 KFP15488.1 - 0.39 10.6 7.0 1.8 8.5 0.7 4.2 4 1 0 4 4 4 0 EF hand RraB PF06877.11 KFP15488.1 - 0.58 10.9 3.9 0.41 11.4 1.4 2.0 2 0 0 2 2 1 0 Regulator of ribonuclease activity B PIN_8 PF18476.1 KFP15488.1 - 1.2 8.9 7.0 9.1 6.1 0.4 2.4 2 0 0 2 2 2 0 PIN like domain IZUMO PF15005.6 KFP15488.1 - 1.9 9.0 6.4 1.6 9.3 0.2 2.4 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Uso1_p115_C PF04871.13 KFP15488.1 - 3.4 8.0 11.7 3.1 8.2 3.4 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region eIF_4EBP PF05456.11 KFP15490.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tmemb_55A PF09788.9 KFP15492.1 - 1.6e-97 325.4 16.4 1.8e-97 325.3 16.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A zf-BED PF02892.15 KFP15492.1 - 0.015 15.3 9.3 0.4 10.7 0.0 3.9 3 1 1 4 4 4 0 BED zinc finger zinc_ribbon_4 PF13717.6 KFP15492.1 - 0.48 10.4 0.0 0.48 10.4 0.0 4.8 5 1 0 5 5 5 0 zinc-ribbon domain OTU PF02338.19 KFP15493.1 - 9.2e-33 113.4 1.4 1.5e-32 112.8 0.0 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFP15493.1 - 3.3e-09 36.5 0.1 4.9e-05 22.9 0.0 2.8 1 1 2 3 3 3 2 Peptidase C65 Otubain IFP_35_N PF07334.13 KFP15493.1 - 0.031 14.3 3.9 0.071 13.2 3.9 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DDHD PF02862.17 KFP15493.1 - 0.4 10.8 2.2 0.45 10.7 2.2 1.1 1 0 0 1 1 1 0 DDHD domain NHR2 PF08788.11 KFP15494.1 - 4.7e-40 135.2 8.8 1.5e-39 133.6 8.8 1.9 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.14 KFP15494.1 - 2.2e-34 117.4 1.4 4.2e-34 116.5 1.4 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.18 KFP15494.1 - 2.8e-07 30.5 18.2 2.8e-07 30.5 18.2 2.0 2 0 0 2 2 2 1 MYND finger Efg1 PF10153.9 KFP15494.1 - 0.026 14.9 2.0 0.079 13.3 2.0 1.8 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DUF3731 PF12531.8 KFP15494.1 - 0.1 12.4 3.7 0.037 13.8 1.0 1.6 2 0 0 2 2 2 0 DNA-K related protein DUF4434 PF14488.6 KFP15494.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4434) MAJIN PF15077.6 KFP15494.1 - 0.3 10.8 3.5 0.62 9.8 3.5 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein vATP-synt_E PF01991.18 KFP15494.1 - 1.1 8.6 12.4 1.8 8.0 12.4 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ARGLU PF15346.6 KFP15494.1 - 2.1 8.2 14.0 0.2 11.5 7.0 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DivIVA PF05103.13 KFP15494.1 - 3.2 7.8 9.1 7.7 6.6 9.1 1.6 1 0 0 1 1 1 0 DivIVA protein TRIQK PF15168.6 KFP15498.1 - 2.4e-25 88.2 0.8 2.6e-25 88.1 0.8 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family TNFR_16_TM PF18422.1 KFP15498.1 - 3.9 7.5 4.8 5.8 7.0 4.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain FAM92 PF06730.11 KFP15502.1 - 7.8e-102 339.4 9.8 9e-102 339.2 9.8 1.0 1 0 0 1 1 1 1 FAM92 protein P4Ha_N PF08336.11 KFP15502.1 - 0.0043 17.1 1.1 0.0043 17.1 1.1 2.2 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Vps5 PF09325.10 KFP15502.1 - 0.012 15.2 8.1 1.2 8.6 5.9 3.0 2 1 1 3 3 3 0 Vps5 C terminal like HTH_42 PF06224.12 KFP15502.1 - 0.025 14.1 0.3 0.036 13.6 0.3 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain CemA PF03040.14 KFP15502.1 - 0.17 11.8 1.6 0.28 11.1 1.6 1.3 1 0 0 1 1 1 0 CemA family FlgN PF05130.12 KFP15502.1 - 0.19 12.2 6.2 0.17 12.4 4.7 1.6 2 0 0 2 2 2 0 FlgN protein RRM_1 PF00076.22 KFP15503.1 - 2.6e-24 84.8 0.1 5.6e-06 26.1 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meckelin PF09773.9 KFP15504.1 - 0 1144.4 13.1 0 1144.4 13.1 1.7 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) NCD3G PF07562.14 KFP15504.1 - 0.045 13.7 13.2 0.027 14.4 5.1 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Phage_tail_X PF05489.12 KFP15504.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X PP2C PF00481.21 KFP15505.1 - 7.5e-37 127.4 0.0 6.1e-36 124.4 0.0 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C Ras PF00071.22 KFP15506.1 - 4.9e-31 107.5 0.1 1.4e-30 106.0 0.1 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFP15506.1 - 3.6e-09 36.9 0.0 8.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFP15506.1 - 4.3e-05 23.1 0.1 0.00022 20.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KFP15506.1 - 4.4e-05 23.5 0.0 8.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP15506.1 - 0.00054 19.9 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase pXO2-34 PF17362.2 KFP15506.1 - 0.036 13.9 0.6 16 5.4 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function Dynamin_N PF00350.23 KFP15506.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.2 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 KFP15506.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP15506.1 - 0.071 13.4 0.1 39 4.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2369 PF10179.9 KFP15506.1 - 0.092 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Myb_DNA-bind_5 PF13873.6 KFP15507.1 - 1.1e-21 76.6 0.1 1.1e-21 76.6 0.1 2.8 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFP15507.1 - 0.066 13.6 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C3HC4_2 PF13923.6 KFP15508.1 - 1.1e-09 38.0 8.5 1.1e-09 38.0 8.5 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KFP15508.1 - 7.8e-08 32.9 4.0 7.8e-08 32.9 4.0 3.4 1 1 2 3 3 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 KFP15508.1 - 1.6e-07 31.0 8.0 1.6e-07 31.0 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP15508.1 - 1.3e-06 28.4 6.4 1.3e-06 28.4 6.4 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP15508.1 - 1.5e-06 28.4 8.4 1.5e-06 28.4 8.4 3.0 2 1 0 2 2 1 1 Ring finger domain Sina PF03145.16 KFP15508.1 - 2.8e-06 27.4 10.1 1.2e-05 25.4 3.2 2.9 1 1 2 3 3 3 2 Seven in absentia protein family zf-RING_UBOX PF13445.6 KFP15508.1 - 3.8e-06 26.8 9.3 3.8e-06 26.8 9.3 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP15508.1 - 6.3e-06 26.0 3.5 6.3e-06 26.0 3.5 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP15508.1 - 0.00033 20.5 1.9 0.00033 20.5 1.9 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KFP15508.1 - 0.0011 18.7 7.3 0.0011 18.7 7.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF1640 PF07798.11 KFP15508.1 - 0.0049 16.9 8.4 0.0084 16.2 8.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) zf-TRAF_2 PF15965.5 KFP15508.1 - 0.0085 16.5 4.5 0.0085 16.5 4.5 3.6 2 1 1 3 3 3 1 TRAF-like zinc-finger zf-RING_10 PF16685.5 KFP15508.1 - 0.0088 16.2 7.1 0.027 14.6 7.1 2.0 1 1 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KFP15508.1 - 0.0095 15.9 6.0 0.0095 15.9 6.0 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP15508.1 - 0.021 15.1 11.0 0.021 15.1 11.0 4.1 3 2 1 4 4 4 0 RING-H2 zinc finger domain GCN5L1 PF06320.13 KFP15508.1 - 0.065 13.4 5.6 0.1 12.8 5.6 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Utp12 PF04003.12 KFP15508.1 - 0.088 13.1 1.9 12 6.2 0.5 2.5 2 1 0 2 2 2 0 Dip2/Utp12 Family LPP PF04728.13 KFP15508.1 - 0.23 11.9 1.2 0.64 10.5 1.2 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Fzo_mitofusin PF04799.13 KFP15508.1 - 0.35 10.4 6.6 0.64 9.6 6.6 1.5 1 0 0 1 1 1 0 fzo-like conserved region Spc7 PF08317.11 KFP15508.1 - 0.88 8.4 12.1 1.2 8.0 12.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFP15508.1 - 1.1 9.4 5.1 1.8 8.6 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IFT20 PF14931.6 KFP15508.1 - 1.7 8.8 11.8 1.4 9.1 8.8 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 MRPL52 PF18699.1 KFP15508.1 - 7.9 6.7 8.8 8.5 6.6 7.6 1.6 1 1 0 1 1 1 0 Mitoribosomal protein mL52 VIR_N PF15912.5 KFP15509.1 - 5.1e-97 324.6 15.8 5.1e-97 324.6 15.8 2.3 1 1 1 2 2 2 1 Virilizer, N-terminal SDA1 PF05285.12 KFP15509.1 - 0.046 13.1 25.0 0.078 12.4 25.0 1.3 1 0 0 1 1 1 0 SDA1 RRM_1 PF00076.22 KFP15510.1 - 2.3e-15 56.2 0.0 0.00053 19.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFP15510.1 - 0.21 11.8 0.0 30 4.8 0.0 3.1 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Dpy19 PF10034.9 KFP15511.1 - 6.2e-213 708.7 31.8 8.3e-213 708.2 31.8 1.1 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Complex1_LYR_1 PF13232.6 KFP15511.1 - 0.082 13.5 0.1 0.25 12.0 0.1 1.8 1 0 0 1 1 1 0 Complex1_LYR-like DUF4405 PF14358.6 KFP15511.1 - 0.11 13.1 3.9 4.5 7.9 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Cadherin PF00028.17 KFP15513.1 - 1.4e-211 685.7 18.8 7.3e-20 71.2 0.2 15.4 15 0 0 15 15 15 14 Cadherin domain Cadherin_C PF01049.17 KFP15513.1 - 3.1e-41 141.1 0.4 7e-41 139.9 0.4 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.24 KFP15513.1 - 7.8e-34 117.0 1.2 2.9e-19 69.9 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP15513.1 - 7.5e-28 97.4 0.0 2.4e-13 50.4 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP15513.1 - 4.8e-14 52.4 49.5 5.3e-06 26.6 8.0 4.6 4 0 0 4 4 4 4 EGF-like domain Cadherin_pro PF08758.11 KFP15513.1 - 9.1e-11 41.8 0.0 0.00013 22.0 0.0 7.2 9 0 0 9 9 9 1 Cadherin prodomain like hEGF PF12661.7 KFP15513.1 - 1.9e-09 37.8 37.3 0.0014 19.2 4.2 4.8 4 0 0 4 4 4 4 Human growth factor-like EGF Cadherin_2 PF08266.12 KFP15513.1 - 2.8e-08 33.5 0.0 1.9 8.4 0.0 7.2 8 0 0 8 8 8 2 Cadherin-like RET_CLD1 PF17756.1 KFP15513.1 - 2.3e-07 31.1 0.1 6.8 7.0 0.0 8.1 9 0 0 9 9 8 1 RET Cadherin like domain 1 Y_Y_Y PF07495.13 KFP15513.1 - 5.3e-05 23.1 5.0 0.94 9.5 0.1 4.9 4 0 0 4 4 4 2 Y_Y_Y domain EGF_2 PF07974.13 KFP15513.1 - 0.0004 20.7 58.8 0.004 17.5 9.4 4.2 4 0 0 4 4 3 2 EGF-like domain PKD PF00801.20 KFP15513.1 - 0.02 14.7 2.0 55 3.7 0.0 6.3 6 1 0 6 6 6 0 PKD domain DUF4975 PF16346.5 KFP15513.1 - 0.072 13.2 0.2 0.28 11.2 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Big_3_4 PF13754.6 KFP15513.1 - 0.083 12.6 0.1 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function He_PIG PF05345.12 KFP15513.1 - 0.54 10.5 14.7 0.98 9.7 0.3 6.4 6 1 0 6 6 5 0 Putative Ig domain TPR_2 PF07719.17 KFP15514.1 - 0.00023 21.1 4.1 0.25 11.5 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP15514.1 - 0.0075 15.9 0.6 0.72 9.6 0.2 2.9 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KFP15514.1 - 0.028 14.4 0.7 3 8.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP15514.1 - 0.11 12.4 7.3 2.6 8.0 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP15514.1 - 0.24 11.7 6.9 7.6 7.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP15514.1 - 2.8 8.2 6.1 1.2 9.4 0.4 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Cyclin_N PF00134.23 KFP15515.1 - 1.3e-39 134.8 1.5 2.5e-39 133.9 1.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP15515.1 - 1.3e-17 64.0 0.1 2.7e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DOR PF14839.6 KFP15516.1 - 2.6e-81 273.2 8.1 5.4e-81 272.2 8.1 1.5 1 1 0 1 1 1 1 DOR family Thioredoxin_7 PF13899.6 KFP15516.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 KFP15516.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin SQS_PSY PF00494.19 KFP15518.1 - 8.3e-53 179.6 0.1 9.9e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase FYVE PF01363.21 KFP15519.1 - 6.5e-19 67.8 7.4 1.5e-18 66.7 7.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFP15519.1 - 1.2e-10 41.8 0.6 4.7e-10 39.9 0.1 2.1 2 1 1 3 3 3 1 PH domain FYVE_2 PF02318.16 KFP15519.1 - 0.00082 19.6 4.9 0.0015 18.8 4.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 KFP15519.1 - 0.0029 17.4 0.6 0.086 12.6 0.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 KFP15519.1 - 0.011 15.5 0.1 0.056 13.3 0.1 2.0 1 1 0 1 1 1 0 PH domain IQ_SEC7_PH PF16453.5 KFP15519.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF1835 PF08874.10 KFP15519.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1835) zf-HYPF PF07503.12 KFP15519.1 - 4 7.3 7.8 14 5.6 7.8 2.0 1 1 0 1 1 1 0 HypF finger zf-B_box PF00643.24 KFP15519.1 - 6.1 7.1 9.4 5.8 7.2 6.3 2.4 2 1 0 2 2 2 0 B-box zinc finger RMP PF14996.6 KFP15520.1 - 1.4e-52 178.1 6.0 1.5e-52 177.9 6.0 1.0 1 0 0 1 1 1 1 Retinal Maintenance RVT_1 PF00078.27 KFP15521.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UCR_14kD PF02271.16 KFP15525.1 - 4.9e-40 135.5 1.0 5.7e-40 135.3 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit mTERF PF02536.14 KFP15526.1 - 1.7e-28 99.5 0.8 2.1e-28 99.2 0.8 1.1 1 0 0 1 1 1 1 mTERF HHH_4 PF14490.6 KFP15526.1 - 0.18 11.8 0.1 32 4.6 0.0 3.4 2 2 2 4 4 4 0 Helix-hairpin-helix containing domain PSS PF03034.15 KFP15527.1 - 2.4e-105 352.2 23.8 2.4e-105 352.2 23.8 1.8 2 0 0 2 2 2 1 Phosphatidyl serine synthase Cyt_b-c1_8 PF10890.8 KFP15527.1 - 0.096 13.1 0.1 0.33 11.4 0.1 1.9 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Peptidase_C1 PF00112.23 KFP15527.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Papain family cysteine protease Syndecan PF01034.20 KFP15529.1 - 5e-30 103.2 0.0 9.2e-30 102.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain DUF2721 PF11026.8 KFP15529.1 - 0.037 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Peptidase_M50 PF02163.22 KFP15529.1 - 0.046 13.0 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 DUF2207 PF09972.9 KFP15529.1 - 0.048 12.4 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 KFP15529.1 - 0.059 13.6 2.9 0.24 11.7 2.9 1.9 1 1 0 1 1 1 0 Glycophorin A DUF2407_C PF13373.6 KFP15529.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain TGF_beta_GS PF08515.12 KFP15529.1 - 0.24 10.9 0.9 0.65 9.5 0.9 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif MtrF PF09472.10 KFP15529.1 - 0.39 10.1 2.9 0.67 9.4 2.9 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glypican PF01153.19 KFP15529.1 - 0.69 8.7 2.0 0.83 8.4 2.0 1.1 1 0 0 1 1 1 0 Glypican PA PF02225.22 KFP15530.1 - 0.00085 19.3 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 KFP15531.1 - 7.3e-22 78.0 0.0 8.3e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFP15531.1 - 1.6e-08 34.5 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 dbPDZ_assoc PF16610.5 KFP15531.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 RVT_1 PF00078.27 KFP15532.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LYRIC PF15686.5 KFP15534.1 - 1.9e-96 324.2 27.1 1.9e-96 324.2 27.1 2.2 1 1 1 2 2 2 1 Lysine-rich CEACAM1 co-isolated protein family Mtp PF03821.16 KFP15535.1 - 1e-12 48.2 3.3 1e-07 31.8 0.5 2.0 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter Tetraspanin PF00335.20 KFP15535.1 - 0.015 15.0 1.2 0.015 15.0 1.2 2.0 1 1 1 2 2 2 0 Tetraspanin family DUF4728 PF15860.5 KFP15535.1 - 0.024 15.3 10.0 0.6 10.8 10.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) Ribosomal_L7Ae PF01248.26 KFP15537.1 - 2.8e-26 91.1 0.1 3.1e-26 90.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 KFP15537.1 - 0.028 14.5 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribonuc_L-PSP PF01042.21 KFP15538.1 - 1.7e-38 131.3 0.1 1.9e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Corona_6B_7B PF03262.13 KFP15538.1 - 0.038 13.4 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Coronavirus 6B/7B protein Con-6 PF10346.9 KFP15538.1 - 0.069 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Conidiation protein 6 POP1 PF06978.11 KFP15539.1 - 3.5e-38 131.7 27.5 7.9e-22 78.3 1.8 3.1 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KFP15539.1 - 1.9e-27 95.4 0.8 9.8e-27 93.1 0.1 2.5 2 0 0 2 2 2 1 POPLD (NUC188) domain Mg_trans_NIPA PF05653.14 KFP15540.1 - 1.9e-84 283.3 21.1 2.2e-84 283.1 21.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP15540.1 - 0.0033 17.6 4.4 0.0033 17.6 4.4 3.0 2 1 1 3 3 3 1 EamA-like transporter family LAX PF15681.5 KFP15540.1 - 0.96 8.2 4.9 18 4.0 0.0 2.4 2 1 1 3 3 3 0 Lymphocyte activation family X Ion_trans PF00520.31 KFP15542.1 - 5.4e-41 140.4 5.1 5.4e-41 140.4 5.1 1.4 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.22 KFP15542.1 - 2.4e-31 107.9 0.2 3.7e-30 104.1 0.1 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP15542.1 - 3.6e-13 49.3 3.5 3.6e-13 49.3 3.5 2.1 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFP15542.1 - 0.082 13.0 0.1 0.32 11.1 0.0 2.0 1 1 1 2 2 2 0 BTB/POZ domain DUF2463 PF09591.10 KFP15542.1 - 9.4 6.0 10.4 0.34 10.8 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2463) Pkinase PF00069.25 KFP15543.1 - 8.7e-72 241.6 0.0 1.5e-71 240.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15543.1 - 7e-53 179.6 1.4 1.3e-52 178.7 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 KFP15543.1 - 2.4e-25 88.3 5.1 2.4e-25 88.3 5.1 2.2 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 KFP15543.1 - 3e-06 26.3 2.0 3.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP15543.1 - 0.0091 15.0 0.2 2.8 6.8 0.0 2.3 1 1 1 2 2 2 2 Haspin like kinase domain Abi_2 PF07751.11 KFP15543.1 - 0.051 13.8 0.0 0.051 13.8 0.0 2.1 2 1 0 2 2 2 0 Abi-like protein Selenoprotein_S PF06936.11 KFP15543.1 - 0.071 12.9 2.2 0.16 11.7 2.2 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Fib_succ_major PF09603.10 KFP15543.1 - 0.13 12.9 0.6 0.3 11.7 0.3 1.7 1 1 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) RGS PF00615.19 KFP15545.1 - 1e-09 38.7 0.0 1.3e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain HHH_3 PF12836.7 KFP15545.1 - 0.023 14.9 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif AgrD PF05931.11 KFP15545.1 - 0.13 12.3 0.2 0.65 10.1 0.1 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein IBR PF01485.21 KFP15548.1 - 3.5e-05 23.9 5.2 3.5e-05 23.9 5.2 1.9 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain Phage_holin_8 PF16931.5 KFP15548.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative phage holin DNA_RNApol_7kD PF03604.13 KFP15549.1 - 1.6e-17 62.8 8.8 2.5e-17 62.3 8.8 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.10 KFP15549.1 - 0.00048 19.8 1.0 0.00088 18.9 1.0 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain Cytochrome_C7 PF14522.6 KFP15549.1 - 0.004 17.1 0.4 0.005 16.8 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c DZR PF12773.7 KFP15549.1 - 0.0051 16.8 1.8 0.0065 16.5 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon MCM_OB PF17207.3 KFP15549.1 - 0.0087 15.9 2.1 0.0089 15.9 2.1 1.0 1 0 0 1 1 1 1 MCM OB domain HypA PF01155.19 KFP15549.1 - 0.018 15.0 2.0 0.023 14.7 2.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_13 PF09855.9 KFP15549.1 - 0.089 13.0 0.6 0.089 13.0 0.6 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-Sec23_Sec24 PF04810.15 KFP15549.1 - 1.2 9.3 6.4 14 5.8 0.1 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger IBR PF01485.21 KFP15551.1 - 9.5e-19 67.4 28.5 1.9e-13 50.4 11.5 4.9 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFP15551.1 - 0.0027 18.0 9.8 0.0027 18.0 9.8 4.6 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 KFP15551.1 - 0.0029 17.4 9.3 0.0029 17.4 9.3 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP15551.1 - 0.0053 16.7 8.1 0.0053 16.7 8.1 4.2 4 1 0 4 4 4 1 zinc-RING finger domain Ank_4 PF13637.6 KFP15553.1 - 6.7e-22 77.6 0.6 1.1e-10 41.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP15553.1 - 1e-15 58.1 0.1 4.6e-13 49.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP15553.1 - 1.3e-12 47.7 0.1 1e-10 41.6 0.2 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP15553.1 - 1.7e-11 44.0 4.3 0.00015 22.1 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP15553.1 - 3.1e-10 39.4 2.3 0.00069 19.9 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat RRM_1 PF00076.22 KFP15554.1 - 6e-70 231.0 4.2 4.9e-25 87.1 0.2 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFP15554.1 - 1.2e-32 111.9 0.2 5.7e-32 109.7 0.2 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KFP15554.1 - 1.1e-07 31.5 0.2 0.08 12.5 0.1 3.6 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KFP15554.1 - 2.5e-05 24.3 0.6 1.9 8.6 0.0 3.6 3 0 0 3 3 3 2 Limkain b1 SET_assoc PF11767.8 KFP15554.1 - 5e-05 22.9 0.3 4.4 7.0 0.1 3.5 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KFP15554.1 - 0.00019 21.2 0.0 0.29 11.0 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP15554.1 - 0.0003 20.8 8.7 0.13 12.3 1.0 3.5 4 0 0 4 4 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFP15554.1 - 0.0016 18.4 0.2 6.9 6.8 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ATP-grasp_2 PF08442.10 KFP15554.1 - 0.0017 17.9 0.2 1.4 8.4 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain RRM_7 PF16367.5 KFP15554.1 - 0.0025 17.9 0.7 7.9 6.7 0.0 4.2 2 2 1 3 3 3 1 RNA recognition motif HATPase_c PF02518.26 KFP15554.1 - 0.0027 18.2 0.2 1.7 9.2 0.1 2.3 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OB_RNB PF08206.11 KFP15554.1 - 0.014 15.1 3.0 4.1 7.2 0.1 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 KFP15554.1 - 0.034 14.7 1.2 1.7 9.2 0.2 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT 14-3-3 PF00244.20 KFP15555.1 - 3.3e-107 357.1 8.4 3.7e-107 356.9 8.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.15 KFP15555.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM CSN7a_helixI PF18392.1 KFP15555.1 - 0.072 13.0 1.7 0.19 11.7 0.7 2.1 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Peptidase_C98 PF15499.6 KFP15555.1 - 0.075 12.5 0.3 0.13 11.7 0.3 1.5 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4518 PF15008.6 KFP15555.1 - 0.44 9.7 3.6 6 6.0 3.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) 4F5 PF04419.14 KFP15557.1 - 7.1e-11 42.8 17.3 9.3e-11 42.4 17.3 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 KFP15557.1 - 1.9e-05 24.9 0.2 3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP15557.1 - 0.0027 18.0 0.3 0.0045 17.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 KFP15557.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KFP15557.1 - 0.011 16.5 1.3 0.016 16.0 1.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L44 PF00935.19 KFP15557.1 - 0.013 15.9 4.0 0.016 15.7 4.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L44 DUF629 PF04780.12 KFP15557.1 - 0.02 13.4 1.4 0.021 13.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-met2 PF12907.7 KFP15557.1 - 0.052 13.7 4.8 0.37 11.0 4.8 2.2 1 1 0 1 1 1 0 Zinc-binding PLATZ PF04640.14 KFP15557.1 - 0.054 14.1 1.7 0.072 13.7 1.7 1.2 1 0 0 1 1 1 0 PLATZ transcription factor EF-hand_7 PF13499.6 KFP15561.1 - 3e-23 82.1 0.7 6.1e-12 45.8 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP15561.1 - 3.3e-20 70.1 4.8 2e-07 30.1 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP15561.1 - 1.4e-18 65.2 1.4 1.6e-06 27.6 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP15561.1 - 2e-18 65.0 4.5 4.7e-06 25.9 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFP15561.1 - 1e-12 47.7 5.2 8.1e-07 28.8 0.2 4.1 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP15561.1 - 5.7e-05 23.4 0.1 0.086 13.2 0.0 2.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP15561.1 - 0.00078 19.4 0.3 0.15 12.1 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP15561.1 - 0.035 14.3 0.1 8.5 6.7 0.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain Fe_hyd_SSU PF02256.17 KFP15561.1 - 0.08 13.0 0.2 7 6.8 0.0 2.9 2 1 1 3 3 3 0 Iron hydrogenase small subunit Ribonuc_red_sm PF00268.21 KFP15563.1 - 2.2e-123 411.1 0.7 2.7e-123 410.9 0.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HSP20 PF00011.21 KFP15564.1 - 3.8e-11 43.0 0.1 4.3e-11 42.9 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family zf-C2H2 PF00096.26 KFP15565.1 - 4.3e-12 45.8 23.5 0.00043 20.6 3.0 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP15565.1 - 8e-10 38.7 22.1 2.8e-06 27.5 1.9 3.9 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP15565.1 - 5.4e-09 36.1 19.5 0.0033 18.1 1.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP15565.1 - 0.00078 20.0 6.2 1.9 9.2 0.2 3.5 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP15565.1 - 0.018 15.3 7.4 0.04 14.2 6.7 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KFP15565.1 - 0.043 14.1 6.0 0.16 12.3 1.2 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 KFP15565.1 - 0.071 12.8 0.5 0.071 12.8 0.5 2.6 3 0 0 3 3 2 0 C2H2 Hakai zinc finger domain GcpE PF04551.14 KFP15565.1 - 0.24 10.4 0.4 14 4.6 0.1 2.1 2 0 0 2 2 2 0 GcpE protein zf-TRAF PF02176.18 KFP15565.1 - 0.46 11.2 4.3 0.2 12.4 1.0 2.1 1 1 0 1 1 1 0 TRAF-type zinc finger TEBP_beta PF07404.11 KFP15565.1 - 0.88 8.9 4.4 1.5 8.1 4.4 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) zf-C2HC_2 PF13913.6 KFP15565.1 - 3.5 7.6 7.7 5.6 7.0 0.3 3.4 2 1 1 3 3 3 0 zinc-finger of a C2HC-type Orn_Arg_deC_N PF02784.16 KFP15567.1 - 2.1e-77 259.9 0.0 2.6e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFP15567.1 - 2.3e-19 69.4 0.0 2.7e-19 69.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain V-ATPase_C PF03223.15 KFP15570.1 - 2e-148 494.7 9.2 2.3e-148 494.5 9.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Folliculin PF11704.8 KFP15570.1 - 0.1 12.5 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Frizzled PF01534.17 KFP15571.1 - 3.1e-118 394.6 17.8 4.3e-118 394.1 17.8 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP15571.1 - 4.2e-22 78.9 7.2 1.2e-21 77.4 7.2 1.8 1 0 0 1 1 1 1 Fz domain Folate_rec PF03024.14 KFP15571.1 - 0.0075 16.2 1.5 0.0075 16.2 1.5 1.8 2 0 0 2 2 2 1 Folate receptor family PIN_8 PF18476.1 KFP15571.1 - 0.081 12.8 1.8 0.12 12.2 1.8 1.2 1 0 0 1 1 1 0 PIN like domain LapA_dom PF06305.11 KFP15571.1 - 0.17 11.7 0.4 0.85 9.5 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RseC_MucC PF04246.12 KFP15571.1 - 0.94 9.4 4.3 1.1 9.3 0.1 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Collagen PF01391.18 KFP15572.1 - 6.1e-07 29.1 7.4 1e-06 28.4 7.4 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mito_carr PF00153.27 KFP15573.1 - 5.3e-62 205.8 3.1 2.3e-22 78.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sof1 PF04158.14 KFP15574.1 - 1.4e-35 121.4 9.1 2.3e-35 120.7 9.1 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KFP15574.1 - 3.4e-21 75.2 12.5 0.00045 21.0 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 KFP15574.1 - 2.6e-06 27.5 0.9 0.0016 18.4 0.1 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFP15574.1 - 9.2e-06 25.9 0.0 0.046 14.0 0.0 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP15574.1 - 0.013 14.5 0.1 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP15574.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DC_STAMP PF07782.13 KFP15579.1 - 1.1e-59 201.6 3.6 1.1e-59 201.6 3.6 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein DUF3094 PF11293.8 KFP15579.1 - 0.21 11.3 0.7 10 5.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Holin_SPP1 PF04688.13 KFP15579.1 - 0.21 11.8 1.2 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 SPP1 phage holin CUB PF00431.20 KFP15580.1 - 9.6e-47 157.9 1.5 5.7e-25 87.8 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFP15580.1 - 1.7e-36 124.1 85.0 3.1e-11 43.3 14.9 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A zf-C2H2 PF00096.26 KFP15581.1 - 4.3e-10 39.5 50.6 0.011 16.1 0.3 8.8 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP15581.1 - 6.6e-09 35.8 52.5 0.05 13.9 0.7 8.5 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP15581.1 - 4.6e-08 33.2 48.8 0.23 12.4 0.1 8.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 KFP15581.1 - 1.4e-07 31.6 51.0 0.0096 16.3 0.7 8.6 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP15581.1 - 0.081 13.2 22.1 0.025 14.9 5.2 5.7 6 0 0 6 6 6 0 C2H2-type zinc ribbon GATA PF00320.27 KFP15581.1 - 0.45 10.2 4.2 14 5.4 0.0 3.6 3 0 0 3 3 3 0 GATA zinc finger zf-C2H2_3 PF13878.6 KFP15581.1 - 4 7.4 12.9 13 5.7 0.1 5.9 6 0 0 6 6 6 0 zinc-finger of acetyl-transferase ESCO TLD PF07534.16 KFP15584.1 - 8.1e-40 136.3 0.1 9.3e-40 136.1 0.1 1.0 1 0 0 1 1 1 1 TLD Costars PF14705.6 KFP15585.1 - 1.3e-32 111.7 0.0 2.6e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Costars Fibrinogen_C PF00147.18 KFP15586.1 - 2.5e-69 233.5 5.6 3.4e-69 233.0 5.6 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain HlyD_2 PF12700.7 KFP15586.1 - 2.1 7.0 16.7 4 6.1 16.7 1.4 1 0 0 1 1 1 0 HlyD family secretion protein FapA PF03961.13 KFP15586.1 - 3.4 6.2 13.9 4.7 5.7 13.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A JAKMIP_CC3 PF16034.5 KFP15586.1 - 5.1 7.0 27.5 0.78 9.7 15.1 2.3 1 1 1 2 2 2 0 JAKMIP CC3 domain eIF3_N PF09440.10 KFP15588.1 - 2e-31 109.2 2.4 2e-31 109.2 2.4 2.0 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFP15588.1 - 2.4e-19 69.8 0.2 1e-18 67.8 0.0 2.2 3 0 0 3 3 3 1 PCI domain HD_assoc PF13286.6 KFP15588.1 - 0.05 14.1 1.4 2.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain CSN8_PSD8_EIF3K PF10075.9 KFP15588.1 - 0.14 12.2 1.0 0.69 9.9 0.0 2.6 4 0 0 4 4 4 0 CSN8/PSMD8/EIF3K family TPR_19 PF14559.6 KFP15591.1 - 5.2e-11 42.9 7.7 9.6e-06 26.0 1.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP15591.1 - 1.1e-10 41.4 6.8 0.0052 17.5 0.6 5.3 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP15591.1 - 2.2e-10 39.8 10.1 0.00017 21.4 0.5 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP15591.1 - 1.9e-07 31.6 1.1 0.55 10.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP15591.1 - 4.4e-07 29.4 4.5 0.061 13.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP15591.1 - 6.1e-05 22.9 10.8 0.051 13.8 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP15591.1 - 0.0028 18.2 6.5 5.8 7.8 0.1 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP15591.1 - 0.0039 17.3 1.0 0.72 10.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP15591.1 - 0.0045 16.9 1.6 5 7.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFP15591.1 - 0.0072 16.8 8.4 0.23 11.9 0.4 3.1 1 1 1 3 3 3 2 Alkyl sulfatase dimerisation NARP1 PF12569.8 KFP15591.1 - 0.012 14.6 9.4 0.0082 15.1 5.3 2.3 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 KFP15591.1 - 0.029 14.7 1.5 0.55 10.6 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFP15591.1 - 0.079 12.6 0.4 4.7 6.9 0.3 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 KFP15591.1 - 0.081 13.2 9.8 0.32 11.3 3.3 3.5 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 MyTH4 PF00784.17 KFP15591.1 - 0.15 12.6 1.4 23 5.5 0.2 3.3 2 1 1 3 3 3 0 MyTH4 domain TPR_17 PF13431.6 KFP15591.1 - 0.24 11.8 6.0 1.7 9.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribonuclease_T2 PF00445.18 KFP15591.1 - 1.4 9.1 4.5 3.4 7.9 4.5 1.7 1 1 0 1 1 1 0 Ribonuclease T2 family TPR_12 PF13424.6 KFP15591.1 - 1.5 9.1 12.8 1.1 9.6 1.3 3.8 3 1 0 4 4 3 0 Tetratricopeptide repeat Neurensin PF14927.6 KFP15592.1 - 6.9e-08 32.3 0.0 9.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Neurensin Renin_r PF07850.14 KFP15592.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Renin receptor-like protein 7tm_1 PF00001.21 KFP15594.1 - 4.8e-51 173.6 24.9 6.8e-51 173.1 24.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP15594.1 - 5.2e-10 39.1 24.8 1.1e-09 38.1 24.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP15594.1 - 7.7e-08 32.3 23.6 7.7e-08 32.3 23.6 2.4 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP15594.1 - 8.8e-06 25.7 19.0 1.7e-05 24.7 12.4 2.2 2 0 0 2 2 2 2 Olfactory receptor Ribosomal_L18A PF01775.17 KFP15594.1 - 0.038 14.1 0.2 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A ISK_Channel PF02060.15 KFP15594.1 - 0.054 13.2 0.1 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Slow voltage-gated potassium channel EnY2 PF10163.9 KFP15595.1 - 1.8e-35 121.2 0.6 2e-35 121.0 0.6 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2294 PF10057.9 KFP15595.1 - 0.066 13.3 0.3 0.66 10.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF3395 PF11875.8 KFP15596.1 - 7.7 6.4 10.8 13 5.6 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Syntaphilin PF15290.6 KFP15597.1 - 2.4e-122 408.5 17.3 4.2e-122 407.7 17.3 1.4 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp FPP PF05911.11 KFP15597.1 - 9.8e-05 20.8 10.5 9.8e-05 20.8 10.5 1.7 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 KFP15597.1 - 0.0046 16.1 10.6 0.0087 15.2 10.6 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KFP15597.1 - 0.016 14.8 6.0 0.029 13.9 6.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec8_exocyst PF04048.14 KFP15597.1 - 0.035 14.0 10.0 0.27 11.1 0.2 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ArAE_1_C PF11728.8 KFP15597.1 - 0.21 11.6 9.6 0.37 10.8 9.6 1.3 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain HR1 PF02185.16 KFP15597.1 - 0.23 11.6 15.5 0.045 13.9 1.6 3.3 2 1 1 3 3 3 0 Hr1 repeat FapA PF03961.13 KFP15597.1 - 0.34 9.5 9.3 0.54 8.8 9.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CALCOCO1 PF07888.11 KFP15597.1 - 0.41 9.5 19.5 0.067 12.1 15.1 1.7 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 KFP15597.1 - 0.48 9.7 5.0 0.81 9.0 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 KFP15597.1 - 0.61 9.4 18.6 0.067 12.5 1.3 2.4 2 1 1 3 3 3 0 FAM76 protein HrpB7 PF09486.10 KFP15597.1 - 0.67 10.3 8.6 2.9 8.3 1.6 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 KFP15597.1 - 0.78 10.2 21.4 1.7 9.1 21.4 1.6 1 1 0 1 1 1 0 Fez1 PKcGMP_CC PF16808.5 KFP15597.1 - 0.86 9.5 14.0 0.11 12.4 5.7 3.1 2 2 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec2p PF06428.11 KFP15597.1 - 1.1 9.3 17.6 0.13 12.3 3.4 3.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF948 PF06103.11 KFP15597.1 - 2.7 8.3 4.5 1.3 9.4 1.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KFP15597.1 - 3.5 7.7 19.1 0.47 10.5 14.7 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RR_TM4-6 PF06459.12 KFP15597.1 - 4.4 7.1 11.7 0.33 10.7 4.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TPR_MLP1_2 PF07926.12 KFP15597.1 - 7.3 6.7 24.4 0.15 12.1 7.1 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 KFP15597.1 - 7.3 6.2 15.2 15 5.2 15.2 1.4 1 0 0 1 1 1 0 GrpE PspA_IM30 PF04012.12 KFP15597.1 - 8.6 5.9 18.1 1.2 8.7 4.6 2.4 1 1 0 2 2 2 0 PspA/IM30 family DUF641 PF04859.12 KFP15597.1 - 8.7 6.7 16.9 0.23 11.8 1.8 2.7 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) 7tm_1 PF00001.21 KFP15600.1 - 2.3e-84 282.8 11.1 3.7e-84 282.1 11.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP15600.1 - 7.8e-18 64.8 22.0 2.2e-13 50.2 14.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP15600.1 - 1e-05 25.1 24.2 0.0021 17.5 17.6 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP15600.1 - 0.00063 19.6 13.1 0.00063 19.6 13.1 2.4 2 1 0 2 2 2 1 Olfactory receptor RAMP4 PF06624.12 KFP15600.1 - 0.012 15.6 0.1 0.7 10.0 0.0 2.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 CcmH PF03918.14 KFP15600.1 - 0.052 12.8 0.1 0.82 9.0 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C biogenesis protein RIFIN PF02009.16 KFP15600.1 - 0.065 13.1 0.5 0.065 13.1 0.5 2.1 2 0 0 2 2 2 0 Rifin DUF3806 PF12713.7 KFP15600.1 - 0.08 12.7 1.0 5.4 6.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3806) Orf78 PF06024.12 KFP15600.1 - 0.099 13.0 7.2 4 7.8 0.6 3.8 3 1 0 3 3 3 0 Orf78 (ac78) TMEM154 PF15102.6 KFP15600.1 - 0.13 12.2 2.7 0.98 9.3 0.3 3.0 3 1 0 3 3 3 0 TMEM154 protein family DUF4307 PF14155.6 KFP15600.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4307) Stevor PF17410.2 KFP15600.1 - 0.79 9.2 3.7 2.2 7.8 3.7 1.7 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Virul_fac_BrkB PF03631.15 KFP15600.1 - 1.4 8.5 13.8 0.039 13.6 1.0 2.9 3 0 0 3 3 3 0 Virulence factor BrkB DUF2207 PF09972.9 KFP15600.1 - 1.8 7.3 9.7 10 4.7 0.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1230 PF06799.11 KFP15600.1 - 7.5 6.7 10.6 2.3 8.3 0.8 2.6 2 1 0 2 2 2 0 Conserved in the green lineage and diatoms 27 TPR_2 PF07719.17 KFP15601.1 - 7.6e-13 47.5 10.4 2.8e-06 27.0 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP15601.1 - 8.1e-12 44.4 13.9 1.2e-05 24.9 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP15601.1 - 7.9e-07 28.8 10.8 2.9e-05 23.9 0.3 3.5 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP15601.1 - 1e-06 29.1 2.6 0.00036 21.0 0.2 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP15601.1 - 1.2e-05 24.9 3.6 0.049 13.3 0.5 3.4 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 KFP15601.1 - 1.2e-05 25.8 0.4 0.0034 18.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP15601.1 - 1.5e-05 25.2 3.8 0.0039 17.4 1.3 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP15601.1 - 5.8e-05 22.8 3.1 0.89 9.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT PF02985.22 KFP15601.1 - 0.0001 22.2 1.0 2.3 8.7 0.0 4.9 5 0 0 5 5 4 1 HEAT repeat Arm PF00514.23 KFP15601.1 - 0.00015 21.6 6.0 9 6.5 0.0 6.1 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat ANAPC3 PF12895.7 KFP15601.1 - 0.00017 21.8 10.0 0.00018 21.6 7.3 2.6 3 1 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP15601.1 - 0.00038 20.9 1.0 0.038 14.6 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP15601.1 - 0.00062 19.8 4.8 0.028 14.5 0.1 3.5 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KFP15601.1 - 0.0007 20.2 0.1 0.8 10.7 0.0 3.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Cnd1 PF12717.7 KFP15601.1 - 0.0074 16.3 5.1 0.042 13.9 0.1 4.1 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP15601.1 - 0.0097 16.3 0.8 1.4 9.3 0.1 4.3 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KFP15601.1 - 0.012 16.1 1.0 23 5.6 0.0 4.2 5 0 0 5 5 4 0 HEAT-like repeat Arm_2 PF04826.13 KFP15601.1 - 0.079 12.4 1.6 3.3 7.1 0.3 2.8 2 1 0 2 2 2 0 Armadillo-like DUF1576 PF07613.11 KFP15601.1 - 0.083 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) BTAD PF03704.17 KFP15601.1 - 0.092 13.2 0.5 0.52 10.7 0.3 2.3 2 1 0 2 2 1 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KFP15601.1 - 0.12 12.5 0.0 0.45 10.7 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 KFP15601.1 - 2.4 8.9 6.6 0.62 10.8 2.0 2.3 2 1 0 2 2 2 0 U3 snoRNA associated PTPS PF01242.19 KFP15602.1 - 3.2e-32 111.1 0.0 3.8e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RPE65 PF03055.15 KFP15603.1 - 1.5e-130 436.5 0.1 1.7e-130 436.4 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein IL1 PF00340.19 KFP15604.1 - 9.9e-10 38.1 0.2 1.5e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 CybS PF05328.12 KFP15605.1 - 1.1e-22 80.2 1.1 1.3e-22 79.9 1.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit NKAP PF15692.5 KFP15606.1 - 6e-22 78.2 25.5 6e-22 78.2 25.5 4.9 2 1 4 6 6 6 1 NF-kappa-B-activating protein Macoilin PF09726.9 KFP15606.1 - 0.38 9.3 31.3 0.48 8.9 31.3 1.1 1 0 0 1 1 1 0 Macoilin family 2-oxoacid_dh PF00198.23 KFP15608.1 - 1.3e-80 270.2 0.1 1.8e-80 269.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFP15608.1 - 1e-31 108.6 0.9 2.5e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 KFP15608.1 - 1.4e-17 63.7 0.4 1.4e-17 63.7 0.4 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFP15608.1 - 0.00016 21.4 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like DIX PF00778.17 KFP15609.1 - 1.9e-30 104.5 0.1 3.5e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 DIX domain CH PF00307.31 KFP15609.1 - 1.9e-17 63.4 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP15609.1 - 1.9e-06 27.6 0.3 0.0044 16.8 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain LMP PF04778.12 KFP15609.1 - 0.091 12.7 9.3 0.2 11.6 8.1 2.2 1 1 0 1 1 1 0 LMP repeated region Spc7 PF08317.11 KFP15609.1 - 5.8 5.7 34.3 0.1 11.4 25.3 2.4 2 1 1 3 3 3 0 Spc7 kinetochore protein HSP20 PF00011.21 KFP15610.1 - 1.8e-19 69.8 0.0 2.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFP15610.1 - 4.9e-06 26.6 0.0 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.21 KFP15611.1 - 3.1e-27 94.7 0.1 3.7e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.18 KFP15611.1 - 4.5e-24 84.4 0.8 7.1e-24 83.7 0.8 1.3 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal ArsA_HSP20 PF17886.1 KFP15611.1 - 0.0024 17.4 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF2431 PF10354.9 KFP15612.1 - 1.9e-25 90.0 0.0 4.4e-25 88.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 KFP15612.1 - 3.5e-16 59.4 0.0 7.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.20 KFP15612.1 - 0.0014 18.2 0.1 0.0063 16.0 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) Glyco_transf_22 PF03901.17 KFP15613.1 - 7.5e-121 404.3 31.9 8.8e-121 404.0 31.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4231 PF14015.6 KFP15613.1 - 0.69 10.4 0.0 0.69 10.4 0.0 2.9 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) Pkinase PF00069.25 KFP15614.1 - 1.7e-68 230.8 0.0 2.9e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15614.1 - 1.6e-36 125.9 0.0 2.7e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP15614.1 - 2.5e-08 33.6 0.0 6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP15614.1 - 9.3e-05 21.5 0.2 0.00034 19.7 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFP15614.1 - 0.031 13.6 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTG PF07742.12 KFP15615.1 - 6.4e-44 148.5 0.1 9.1e-44 148.0 0.1 1.2 1 0 0 1 1 1 1 BTG family PD-C2-AF1 PF09310.10 KFP15616.1 - 6.9e-135 448.2 14.1 7.9e-135 448.0 14.1 1.0 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 DUF5566 PF17721.1 KFP15617.1 - 8.8e-119 395.9 23.3 9.8e-119 395.8 23.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5566) zf-C2H2 PF00096.26 KFP15618.1 - 1.3e-18 66.3 85.1 6.6e-05 23.1 5.8 10.2 10 1 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP15618.1 - 8.2e-16 57.6 68.7 8.9e-06 25.9 3.3 9.6 11 0 0 11 11 10 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP15618.1 - 1.3e-14 53.6 81.9 7.9e-05 23.2 2.3 10.7 11 0 0 11 11 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP15618.1 - 4.1e-06 26.9 40.7 0.0076 16.5 0.5 7.4 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFP15618.1 - 0.00044 20.0 5.7 0.00044 20.0 5.7 9.0 9 1 0 9 9 9 4 C2H2-type zinc-finger domain zf-met PF12874.7 KFP15618.1 - 0.0005 20.4 36.3 0.25 11.8 0.1 6.7 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP15618.1 - 0.00065 19.6 13.0 0.0064 16.5 1.1 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Dof PF02701.15 KFP15618.1 - 0.0012 19.0 12.7 0.03 14.5 0.6 3.6 3 0 0 3 3 3 2 Dof domain, zinc finger zf-Di19 PF05605.12 KFP15618.1 - 0.0024 18.1 57.3 0.0032 17.7 7.6 7.3 4 2 1 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFP15618.1 - 0.02 14.8 0.7 0.02 14.8 0.7 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type SLIDE PF09111.10 KFP15618.1 - 0.074 13.1 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 SLIDE ABC2_membrane PF01061.24 KFP15619.1 - 1.1e-47 162.2 23.2 1.6e-47 161.7 23.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFP15619.1 - 5.2e-26 91.8 0.0 8.3e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFP15619.1 - 3.1e-07 30.5 0.0 0.003 17.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP15619.1 - 1.9e-06 27.5 0.3 0.0003 20.3 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFP15619.1 - 0.00023 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 KFP15619.1 - 0.0057 15.4 0.0 0.088 11.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFP15619.1 - 0.018 15.2 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KFP15619.1 - 0.025 15.1 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFP15619.1 - 0.041 13.6 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFP15619.1 - 0.041 13.8 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KFP15619.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KFP15619.1 - 0.091 13.3 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFP15619.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane_3 PF12698.7 KFP15619.1 - 1 8.4 25.6 0.16 11.1 20.5 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF1440 PF07274.12 KFP15619.1 - 2 8.7 6.5 0.82 10.0 1.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) NACHT PF05729.12 KFP15620.1 - 1.3e-07 31.7 0.0 5.2e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain NLRC4_HD2 PF17776.1 KFP15620.1 - 4.3e-07 30.5 0.0 0.0068 16.9 0.0 2.8 2 0 0 2 2 2 2 NLRC4 helical domain HD2 LRR_6 PF13516.6 KFP15620.1 - 5.5e-07 29.1 15.5 0.02 14.9 0.1 6.5 7 0 0 7 7 7 2 Leucine Rich repeat NOD2_WH PF17779.1 KFP15620.1 - 1.4e-05 25.3 2.8 0.00019 21.7 0.8 3.2 2 1 0 2 2 2 1 NOD2 winged helix domain STAS PF01740.21 KFP15620.1 - 0.025 14.2 0.0 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 STAS domain LRR_1 PF00560.33 KFP15620.1 - 0.89 10.3 6.6 22 6.1 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Cbl_N3 PF02762.14 KFP15621.1 - 7.8e-46 153.8 0.0 1.5e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N PF02262.16 KFP15621.1 - 2.1e-45 153.7 0.4 3.6e-45 153.0 0.4 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N2 PF02761.14 KFP15621.1 - 2.2e-41 140.4 0.7 4.6e-41 139.4 0.7 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 KFP15621.1 - 6.2e-13 48.4 9.1 1.2e-12 47.5 9.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP15621.1 - 8.9e-11 41.5 8.3 1.6e-10 40.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP15621.1 - 7.9e-09 35.3 7.9 1.9e-08 34.0 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP15621.1 - 2.3e-08 34.2 7.7 5.6e-08 33.0 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain UBA PF00627.31 KFP15621.1 - 9.9e-07 28.6 0.1 1.7e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain zf-C3HC4_2 PF13923.6 KFP15621.1 - 9.2e-05 22.2 8.1 9.2e-05 22.2 8.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP15621.1 - 0.00031 20.7 4.8 0.00091 19.2 4.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP15621.1 - 0.0051 16.7 10.5 0.01 15.7 10.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KFP15621.1 - 0.023 14.5 9.3 0.049 13.4 9.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFP15621.1 - 0.039 14.2 7.4 0.087 13.1 7.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP15621.1 - 0.11 12.7 11.0 0.12 12.5 8.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFP15621.1 - 3.8 7.7 6.8 11 6.2 6.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 KFP15622.1 - 1.5e-13 50.4 12.7 2.2e-13 49.8 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP15622.1 - 1.6e-07 31.0 10.3 2.7e-07 30.3 10.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP15622.1 - 2e-05 24.8 12.3 3.2e-05 24.2 12.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP15622.1 - 0.017 15.0 12.6 0.034 14.1 12.5 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP15622.1 - 0.32 11.1 5.6 0.75 9.9 5.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_P35 PF03213.14 KFP15622.1 - 1.1 8.5 6.9 1.6 7.9 6.9 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein zf-RING_UBOX PF13445.6 KFP15622.1 - 6.4 6.9 9.6 19 5.4 9.8 1.7 1 1 0 1 1 1 0 RING-type zinc-finger C1q PF00386.21 KFP15623.1 - 8.2e-32 110.1 0.0 1.1e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP15623.1 - 2.3e-10 40.1 32.7 6.4e-08 32.2 32.7 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) FSAP_sig_propep PF03032.15 KFP15623.1 - 0.065 13.3 0.6 0.099 12.7 0.6 1.3 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Fz PF01392.22 KFP15624.1 - 2.2e-24 86.2 0.5 2.2e-24 86.2 0.5 1.9 2 0 0 2 2 2 1 Fz domain CUB PF00431.20 KFP15624.1 - 2.8e-19 69.5 0.0 7.6e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 CUB domain Ldl_recept_a PF00057.18 KFP15624.1 - 5.4e-10 39.3 8.4 5.4e-10 39.3 8.4 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A ig PF00047.25 KFP15625.1 - 2e-06 27.9 0.5 3.4e-06 27.1 0.5 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP15625.1 - 3.3e-06 27.2 1.1 5.5e-06 26.5 1.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP15625.1 - 0.00013 22.5 0.3 0.0002 21.9 0.3 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP15625.1 - 0.01 15.9 0.6 0.022 14.8 0.6 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain Herpes_gE PF02480.16 KFP15625.1 - 0.015 14.1 0.8 0.017 13.9 0.8 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NEAT PF05031.12 KFP15625.1 - 0.064 13.9 0.2 0.12 13.0 0.0 1.5 2 0 0 2 2 2 0 Iron Transport-associated domain Izumo-Ig PF16706.5 KFP15625.1 - 0.073 13.1 0.2 0.14 12.2 0.2 1.6 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain RPA_C PF08784.11 KFP15625.1 - 0.088 13.5 0.1 0.12 13.1 0.1 1.3 1 1 0 1 1 1 0 Replication protein A C terminal PAN_4 PF14295.6 KFP15625.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 PAN domain EphA2_TM PF14575.6 KFP15626.1 - 0.0021 18.9 0.0 0.0025 18.6 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 KFP15626.1 - 0.01 15.8 1.5 0.022 14.8 1.5 1.5 1 1 0 1 1 1 0 Protocadherin Syndecan PF01034.20 KFP15626.1 - 0.047 13.6 0.6 0.079 12.9 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain Cytomega_TRL10 PF06084.11 KFP15626.1 - 0.062 13.3 0.2 0.093 12.8 0.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Flp1_like PF16982.5 KFP15626.1 - 0.063 12.7 1.8 0.1 12.0 1.8 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Adeno_E3_CR2 PF02439.15 KFP15626.1 - 0.069 12.9 2.4 0.11 12.3 2.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Chordopox_A13L PF05961.11 KFP15626.1 - 0.24 11.7 1.7 0.54 10.5 1.6 1.8 1 1 0 1 1 1 0 Chordopoxvirus A13L protein OAF PF14941.6 KFP15628.1 - 1.3e-93 312.9 3.3 1.5e-93 312.8 3.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first Pou PF00157.17 KFP15629.1 - 3.1e-38 129.6 0.6 6.7e-38 128.5 0.2 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP15629.1 - 1.5e-18 66.4 3.3 4e-18 65.0 3.3 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15629.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain HTH_3 PF01381.22 KFP15629.1 - 0.14 12.2 0.2 1.4 9.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix TMEM190 PF15431.6 KFP15630.1 - 1.5 9.0 6.3 0.59 10.3 2.9 1.8 2 0 0 2 2 2 0 Transmembrane protein 190 TRAM_LAG1_CLN8 PF03798.16 KFP15631.1 - 0.00073 19.3 0.2 0.00073 19.3 0.2 1.4 2 0 0 2 2 2 1 TLC domain RGS-like PF09128.11 KFP15633.1 - 1.5e-84 282.4 2.4 1.5e-84 282.4 2.4 3.4 4 0 0 4 4 4 1 Regulator of G protein signalling-like domain PH_16 PF17838.1 KFP15633.1 - 4.5e-45 152.5 1.1 8.5e-45 151.6 1.1 1.5 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFP15633.1 - 7.8e-38 130.5 1.0 7.8e-38 130.5 1.0 2.4 3 0 0 3 3 3 1 RhoGEF domain PDZ PF00595.24 KFP15633.1 - 1.3e-12 47.9 0.2 7.4e-12 45.5 0.5 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP15633.1 - 1.4e-12 47.3 0.1 3.9e-12 45.8 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP15633.1 - 1.8e-07 31.3 0.2 6.1e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PH_13 PF16652.5 KFP15633.1 - 5.3e-07 29.6 0.3 1.7e-06 27.9 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Tricorn_PDZ PF14685.6 KFP15633.1 - 0.1 12.6 0.4 0.37 10.8 0.1 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain AAA_23 PF13476.6 KFP15633.1 - 0.41 11.1 0.0 0.41 11.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain ANF_receptor PF01094.28 KFP15634.1 - 1.6e-61 208.4 0.0 2.6e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP15634.1 - 1.2e-47 161.5 0.1 1.9e-47 160.8 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP15634.1 - 2.3e-44 150.3 0.0 5.4e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP15634.1 - 7.5e-21 74.6 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP15634.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein DUF4462 PF14692.6 KFP15635.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) LRR_9 PF14580.6 KFP15636.1 - 7.1e-12 45.2 2.6 6.3e-09 35.6 0.2 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFP15636.1 - 1.3e-07 31.8 28.6 0.0028 18.0 4.7 5.8 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP15636.1 - 2e-07 30.7 16.5 0.0027 17.4 2.1 4.3 1 1 4 5 5 5 5 Leucine rich repeat Ubiquitin_2 PF14560.6 KFP15636.1 - 2.3e-07 31.2 0.2 8e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KFP15636.1 - 0.0021 17.7 0.5 0.019 14.7 0.5 2.3 1 1 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 KFP15636.1 - 0.069 13.2 17.1 1.5 9.0 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat PB1 PF00564.24 KFP15636.1 - 0.07 13.1 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 PB1 domain APG12 PF04110.13 KFP15636.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 LRR_1 PF00560.33 KFP15636.1 - 7 7.6 15.0 4.7 8.1 0.1 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat Ldl_recept_a PF00057.18 KFP15637.1 - 1.5e-113 370.7 206.0 1.2e-13 51.0 7.8 12.2 11 1 1 12 12 11 11 Low-density lipoprotein receptor domain class A Sortilin-Vps10 PF15902.5 KFP15637.1 - 1.5e-112 376.7 0.0 2.7e-112 375.8 0.0 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFP15637.1 - 3.3e-40 138.2 0.1 3.3e-40 138.2 0.1 5.4 3 2 3 6 6 1 1 Sortilin, neurotensin receptor 3, C-terminal fn3 PF00041.21 KFP15637.1 - 1.4e-31 108.6 16.1 4.7e-09 36.5 0.3 6.4 6 0 0 6 6 6 5 Fibronectin type III domain Ldl_recept_b PF00058.17 KFP15637.1 - 8.8e-24 83.7 5.8 2e-07 31.3 0.1 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B Interfer-bind PF09294.10 KFP15637.1 - 3.1e-05 24.2 15.0 1.3 9.4 0.1 5.8 5 0 0 5 5 5 3 Interferon-alpha/beta receptor, fibronectin type III BNR_6 PF15899.5 KFP15637.1 - 0.0001 22.0 3.3 0.51 10.5 0.8 3.4 2 0 0 2 2 2 2 BNR-Asp box repeat Pur_ac_phosph_N PF16656.5 KFP15637.1 - 0.00043 20.8 16.2 0.16 12.5 0.2 4.9 5 0 0 5 5 4 2 Purple acid Phosphatase, N-terminal domain BNR PF02012.20 KFP15637.1 - 0.00089 18.9 15.7 2.1 8.7 0.2 5.7 5 0 0 5 5 5 1 BNR/Asp-box repeat fn3_2 PF16893.5 KFP15637.1 - 0.0084 16.2 4.7 2.5 8.3 0.0 4.7 5 1 1 6 6 6 1 Fibronectin type III domain DUF3377 PF11857.8 KFP15637.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CHB_HEX_C PF03174.13 KFP15637.1 - 0.19 11.7 0.7 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Tissue_fac PF01108.17 KFP15637.1 - 1.9 8.4 15.9 3.8 7.4 2.1 5.2 4 2 1 5 5 5 0 Tissue factor DUF2205 PF10224.9 KFP15639.1 - 5.9e-28 96.7 4.0 7.6e-28 96.3 4.0 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HALZ PF02183.18 KFP15639.1 - 0.00085 19.5 8.3 0.04 14.1 1.9 3.0 1 1 1 2 2 2 2 Homeobox associated leucine zipper YabA PF06156.13 KFP15639.1 - 0.0063 17.1 3.9 0.0083 16.7 3.8 1.4 1 1 0 1 1 1 1 Initiation control protein YabA Nse5 PF08691.10 KFP15639.1 - 0.0098 14.6 0.2 0.011 14.5 0.2 1.1 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 CENP-H PF05837.12 KFP15639.1 - 0.01 16.2 3.6 0.012 16.0 3.2 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 KFP15639.1 - 0.011 15.9 3.9 0.04 14.0 4.0 1.9 1 1 0 1 1 1 0 bZIP transcription factor FlaC_arch PF05377.11 KFP15639.1 - 0.017 15.5 1.1 0.017 15.5 1.1 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad4 PF08650.10 KFP15639.1 - 0.04 13.9 2.3 0.046 13.7 1.7 1.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 DUF2683 PF10884.8 KFP15639.1 - 0.046 14.0 0.3 0.057 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ZapB PF06005.12 KFP15639.1 - 0.061 13.8 7.5 0.11 13.0 7.5 1.5 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KFP15639.1 - 0.26 11.1 6.0 0.1 12.4 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF349 PF03993.12 KFP15639.1 - 0.29 11.4 3.3 0.49 10.7 2.7 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Guanylate_cyc PF00211.20 KFP15643.1 - 5e-131 433.7 0.7 1.4e-66 223.7 0.2 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFP15643.1 - 6.4e-34 117.8 3.9 6.4e-34 117.8 3.9 2.5 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFP15643.1 - 0.0068 16.9 0.6 0.013 16.1 0.6 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 KFP15643.1 - 0.083 12.3 1.6 0.39 10.1 0.3 2.2 2 0 0 2 2 2 0 Heme NO binding associated Thyroglobulin_1 PF00086.18 KFP15645.1 - 2.5e-19 68.7 3.0 4.6e-19 67.9 3.0 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF4829 PF16111.5 KFP15645.1 - 0.0099 16.7 0.1 0.013 16.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4829) TLV_coat PF00429.19 KFP15649.1 - 4.3e-109 365.7 1.0 4.8e-109 365.6 1.0 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) PSII_Ycf12 PF05969.11 KFP15649.1 - 0.013 15.4 1.1 0.035 14.1 1.1 1.7 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 SlyX PF04102.12 KFP15649.1 - 0.2 12.3 1.9 0.36 11.5 0.1 2.3 2 1 1 3 3 3 0 SlyX TLV_coat PF00429.19 KFP15650.1 - 4.3e-109 365.7 1.0 4.8e-109 365.6 1.0 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) PSII_Ycf12 PF05969.11 KFP15650.1 - 0.013 15.4 1.1 0.035 14.1 1.1 1.7 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 SlyX PF04102.12 KFP15650.1 - 0.2 12.3 1.9 0.36 11.5 0.1 2.3 2 1 1 3 3 3 0 SlyX RVT_1 PF00078.27 KFP15653.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4713 PF15831.5 KFP15655.1 - 1 9.9 3.6 1.9 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Hus1 PF04005.12 KFP15656.1 - 6.6e-86 288.0 0.2 7.4e-86 287.9 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF5087 PF17006.5 KFP15657.1 - 0.00068 19.3 0.8 0.0012 18.5 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5087) HMMR_N PF15905.5 KFP15659.1 - 0.01 15.3 0.9 0.012 15.1 0.9 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 KFP15659.1 - 0.049 13.6 0.1 0.056 13.5 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II zf-NF-X1 PF01422.17 KFP15660.1 - 1.1e-12 47.8 99.5 1.8e-05 24.7 11.7 14.2 13 1 0 13 13 13 7 NF-X1 type zinc finger zf-RING_11 PF17123.5 KFP15661.1 - 3.1e-09 36.4 2.7 6e-09 35.5 2.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFP15661.1 - 1.6e-05 25.2 2.6 2.8e-05 24.3 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 KFP15661.1 - 0.0016 18.3 1.6 0.0026 17.6 1.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 KFP15661.1 - 0.0035 17.2 2.8 0.0068 16.3 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP15661.1 - 0.0049 16.7 2.2 0.0097 15.7 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP15661.1 - 0.0097 15.9 2.7 0.017 15.2 2.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP15661.1 - 0.017 15.1 2.1 0.028 14.4 2.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Orthoreo_P10 PF07204.11 KFP15661.1 - 0.027 14.4 0.6 0.039 13.9 0.6 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LapA_dom PF06305.11 KFP15661.1 - 0.13 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Fumble PF03630.14 KFP15662.1 - 4.1e-94 315.4 0.0 4.6e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Fumble DUF3784 PF12650.7 KFP15662.1 - 0.11 12.7 0.9 0.24 11.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) 7tm_4 PF13853.6 KFP15663.1 - 2.9e-19 69.9 3.8 3.4e-19 69.6 3.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15663.1 - 1e-16 61.1 3.8 1.3e-16 60.8 3.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP15664.1 - 4.5e-48 164.4 9.6 5.4e-48 164.1 9.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15664.1 - 1.5e-28 99.9 13.6 2e-28 99.5 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP15665.1 - 5.4e-32 111.6 1.0 6.2e-32 111.4 1.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15665.1 - 5.3e-13 48.9 0.9 7.1e-13 48.5 0.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PhoLip_ATPase_C PF16212.5 KFP15666.1 - 1.6e-65 221.4 11.5 1.6e-65 221.4 11.5 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KFP15666.1 - 3.4e-12 46.3 0.0 2.2e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP15666.1 - 1.7e-10 41.5 0.3 0.00072 19.9 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP15666.1 - 0.00045 20.0 0.0 0.00088 19.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Formyl_trans_C PF02911.18 KFP15666.1 - 0.11 12.7 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain EF-hand_1 PF00036.32 KFP15667.1 - 5.9e-19 66.1 0.1 9.3e-07 28.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP15667.1 - 3e-18 64.1 0.1 6.3e-07 28.8 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP15667.1 - 1.1e-17 62.6 1.1 2.5e-06 26.7 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFP15667.1 - 1.1e-15 57.8 0.3 4.1e-07 30.4 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP15667.1 - 5.3e-10 39.0 0.0 0.001 18.8 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_2 PF09068.11 KFP15667.1 - 0.0002 21.5 0.2 2 8.6 0.0 3.4 1 1 3 4 4 4 1 EF hand EF-hand_9 PF14658.6 KFP15667.1 - 0.0013 19.0 0.0 6.5 7.2 0.0 3.4 4 1 0 4 4 4 2 EF-hand domain Caleosin PF05042.13 KFP15667.1 - 0.032 14.2 0.0 0.21 11.5 0.0 2.0 1 1 1 2 2 2 0 Caleosin related protein MCM3AP_GANP PF16769.5 KFP15668.1 - 0 1111.5 4.3 0 1111.5 4.3 1.6 2 0 0 2 2 2 1 MCM3AP domain of GANP SAC3_GANP PF03399.16 KFP15668.1 - 5.1e-117 390.4 4.0 5.1e-117 390.4 4.0 1.9 2 0 0 2 2 2 1 SAC3/GANP family CID_GANP PF16766.5 KFP15668.1 - 2.2e-30 104.6 13.0 4.2e-29 100.6 7.0 3.1 2 0 0 2 2 2 2 Binding region of GANP to ENY2 CSN8_PSD8_EIF3K PF10075.9 KFP15668.1 - 3.1e-06 27.2 0.1 9.3e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family UPF0158 PF03682.13 KFP15668.1 - 0.01 15.8 0.8 0.031 14.3 0.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) NleF_casp_inhib PF16809.5 KFP15668.1 - 0.012 15.5 1.4 0.84 9.5 1.0 2.6 2 0 0 2 2 2 0 NleF caspase inhibitor Tobravirus_2B PF05271.11 KFP15668.1 - 0.095 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Tobravirus 2B protein RRM_1 PF00076.22 KFP15668.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CNOT11 PF10155.9 KFP15668.1 - 0.19 11.9 3.2 0.59 10.3 3.2 1.8 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 O-FucT PF10250.9 KFP15669.1 - 6.2e-72 243.1 0.0 7.3e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase A_deamin PF02137.18 KFP15670.1 - 2e-116 389.1 0.0 2.6e-116 388.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFP15670.1 - 3e-27 95.1 0.2 2.3e-13 50.6 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP15670.1 - 0.045 14.0 2.5 2.1 8.7 0.2 3.2 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Clat_adaptor_s PF01217.20 KFP15671.1 - 3.7e-41 140.4 3.7 4.3e-41 140.2 3.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 7tm_4 PF13853.6 KFP15672.1 - 4e-23 82.5 3.4 4.6e-23 82.3 3.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15672.1 - 3.3e-22 79.1 2.2 4.1e-22 78.8 2.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP15672.1 - 2.3e-06 27.2 1.3 2.9e-06 26.8 1.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP15673.1 - 2.4e-30 106.2 11.3 3e-30 105.9 11.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15673.1 - 9.4e-17 61.2 13.0 1.5e-16 60.6 13.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP15673.1 - 0.014 14.8 9.4 0.019 14.4 9.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP15674.1 - 2.5e-10 40.6 0.7 2.7e-10 40.4 0.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_4 PF13853.6 KFP15675.1 - 2.3e-22 80.1 2.9 2.5e-22 79.9 2.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP15675.1 - 4.7e-05 22.9 4.8 6e-05 22.5 4.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RasGAP PF00616.19 KFP15676.1 - 3.7e-59 199.9 0.0 3.7e-59 199.9 0.0 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFP15676.1 - 7.2e-37 126.6 12.2 7.2e-37 126.6 12.2 3.3 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 KFP15676.1 - 2.8e-19 67.0 19.8 7e-06 25.4 0.6 5.3 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.31 KFP15676.1 - 4.1e-19 68.8 0.0 1.7e-18 66.8 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain WW PF00397.26 KFP15676.1 - 0.0028 17.7 4.2 0.0063 16.6 4.2 1.6 1 0 0 1 1 1 1 WW domain bZIP_1 PF00170.21 KFP15676.1 - 0.023 14.8 0.6 0.023 14.8 0.6 4.1 4 0 0 4 4 4 0 bZIP transcription factor IDEAL PF08858.10 KFP15676.1 - 0.2 11.4 5.6 23 4.9 0.1 4.5 4 0 0 4 4 4 0 IDEAL domain Nif11 PF07862.11 KFP15676.1 - 0.48 10.8 4.3 6.1 7.2 0.1 3.7 3 0 0 3 3 3 0 Nif11 domain Fascin PF06268.13 KFP15677.1 - 0.00071 19.8 4.8 3.4 7.9 0.2 3.2 1 1 2 3 3 3 3 Fascin domain Lactococcin PF04369.13 KFP15677.1 - 0.0038 17.3 18.8 2.1 8.5 2.6 4.0 1 1 3 4 4 4 3 Lactococcin-like family GCP_C_terminal PF04130.13 KFP15679.1 - 6.3e-62 209.8 12.7 7.6e-62 209.5 10.5 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP15679.1 - 2e-54 185.3 0.6 2e-54 185.3 0.6 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal His_Phos_2 PF00328.22 KFP15680.1 - 4.6e-130 434.4 0.1 6e-130 434.0 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFP15680.1 - 6.5e-41 138.4 0.3 1.4e-40 137.3 0.3 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFP15680.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Thioredoxin PF00085.20 KFP15681.1 - 1e-44 150.7 0.0 1.7e-31 108.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFP15681.1 - 6.8e-37 127.2 0.4 2.5e-33 115.5 0.4 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFP15681.1 - 2e-06 28.2 0.1 0.0027 18.1 0.1 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP15681.1 - 3.7e-05 24.0 0.0 0.0032 17.7 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.6 KFP15681.1 - 0.00039 20.6 0.2 0.048 13.8 0.0 3.1 3 1 0 3 3 3 1 Thioredoxin Calsequestrin PF01216.17 KFP15681.1 - 0.0032 16.6 0.1 0.0064 15.6 0.0 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 KFP15681.1 - 0.0081 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KFP15681.1 - 0.021 14.5 0.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Redoxin AhpC-TSA PF00578.21 KFP15681.1 - 0.041 13.8 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 KFP15681.1 - 0.068 12.5 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Serinc PF03348.15 KFP15682.1 - 3.7e-69 233.7 8.5 2.2e-68 231.1 8.5 1.8 1 1 0 1 1 1 1 Serine incorporator (Serinc) MFAP1 PF06991.11 KFP15683.1 - 1.5e-78 263.6 30.3 1.5e-78 263.6 30.3 2.1 2 0 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing Peptidase_S8 PF00082.22 KFP15684.1 - 3.2e-24 85.7 3.7 1.4e-11 44.3 0.3 2.2 1 1 0 2 2 2 2 Subtilase family S8_pro-domain PF16470.5 KFP15684.1 - 2.8e-23 82.5 0.3 5.7e-23 81.5 0.3 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain P_proprotein PF01483.20 KFP15684.1 - 8.6e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Furin-like_2 PF15913.5 KFP15684.1 - 0.0056 16.8 0.1 0.0056 16.8 0.1 2.1 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich DUF357 PF04010.13 KFP15684.1 - 0.032 14.3 0.2 0.081 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) V-set PF07686.17 KFP15685.1 - 9.5e-10 38.6 0.0 1e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Urocanase_C PF17392.2 KFP15685.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Urocanase C-terminal domain Ig_3 PF13927.6 KFP15685.1 - 0.068 13.8 0.0 0.076 13.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP15686.1 - 8.4e-12 45.2 0.0 2.4e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP15686.1 - 1.3e-08 35.3 0.0 0.0026 18.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP15686.1 - 6.8e-07 29.4 0.0 0.032 14.4 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP15686.1 - 1.4e-06 28.3 0.0 0.0097 16.0 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP15686.1 - 7.3e-05 22.3 0.0 0.023 14.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP15686.1 - 0.00029 21.1 0.0 0.054 13.8 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin domain MASE4 PF17158.4 KFP15686.1 - 0.025 13.8 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain Receptor_2B4 PF11465.8 KFP15686.1 - 0.059 13.6 0.0 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 GTP_EFTU PF00009.27 KFP15687.1 - 6.1e-46 156.4 0.0 9.3e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFP15687.1 - 1e-38 132.6 9.2 1.7e-38 131.9 9.2 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFP15687.1 - 1.1e-23 83.2 0.0 2.4e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFP15687.1 - 9.8e-23 80.0 0.0 2.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFP15687.1 - 1e-12 48.3 0.0 2.7e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFP15687.1 - 3.1e-08 33.6 0.0 8.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 KFP15687.1 - 0.061 12.6 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin Connexin PF00029.19 KFP15688.1 - 3.4e-97 324.8 0.3 3.9e-97 324.6 0.3 1.0 1 0 0 1 1 1 1 Connexin UPF0542 PF15086.6 KFP15688.1 - 0.1 12.5 0.2 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 TLP-20 PF06088.11 KFP15688.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2254 PF10011.9 KFP15688.1 - 0.14 11.0 0.0 0.94 8.2 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) Reprolysin PF01421.19 KFP15689.1 - 3e-14 53.4 0.1 3.2e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 KFP15689.1 - 0.0031 18.0 0.0 0.0033 18.0 0.0 1.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF3863 PF12979.7 KFP15689.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Reprolysin_5 PF13688.6 KFP15689.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Metallo-peptidase family M12 AAA PF00004.29 KFP15690.1 - 1.2e-57 194.0 0.0 2e-41 141.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 KFP15690.1 - 1e-12 48.0 0.0 3.1e-11 43.3 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_lid_3 PF17862.1 KFP15690.1 - 6.7e-11 41.8 0.4 1.4e-10 40.8 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFP15690.1 - 8.9e-10 39.0 0.2 0.006 16.9 0.1 4.3 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KFP15690.1 - 3.8e-09 36.2 0.9 4e-08 32.9 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 KFP15690.1 - 2.9e-08 34.3 0.0 0.004 17.5 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KFP15690.1 - 3.7e-08 33.3 0.0 0.0091 15.7 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFP15690.1 - 3.9e-08 33.7 0.0 0.0099 16.3 0.0 3.5 4 0 0 4 4 2 2 RNA helicase AAA_2 PF07724.14 KFP15690.1 - 7.3e-08 32.7 0.0 9.7e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFP15690.1 - 6.2e-07 29.5 0.0 0.00092 19.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFP15690.1 - 7.7e-07 29.2 0.0 0.032 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KFP15690.1 - 1.3e-06 27.9 0.0 0.045 13.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KFP15690.1 - 2e-06 28.0 0.0 0.075 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP15690.1 - 2.1e-06 28.3 0.0 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KFP15690.1 - 1.1e-05 24.9 0.1 0.0043 16.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFP15690.1 - 1.4e-05 25.1 0.0 0.65 9.9 0.0 3.9 3 1 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 KFP15690.1 - 3.2e-05 23.7 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFP15690.1 - 3.4e-05 23.8 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KFP15690.1 - 3.6e-05 23.3 0.4 0.36 10.2 0.1 3.7 3 1 0 4 4 4 1 Bacterial TniB protein ATPase_2 PF01637.18 KFP15690.1 - 3.8e-05 23.7 0.1 0.13 12.1 0.1 3.8 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KFP15690.1 - 0.00014 22.3 0.1 1.4 9.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain ATPase PF06745.13 KFP15690.1 - 0.00087 18.7 0.6 0.019 14.3 0.0 3.1 3 1 1 4 4 4 1 KaiC AAA_25 PF13481.6 KFP15690.1 - 0.0016 18.1 0.3 2 7.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 KFP15690.1 - 0.0019 18.0 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFP15690.1 - 0.0021 18.3 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFP15690.1 - 0.0026 17.1 0.0 1.3 8.3 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Sigma54_activat PF00158.26 KFP15690.1 - 0.0028 17.4 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KFP15690.1 - 0.0031 18.0 0.0 0.016 15.7 0.0 2.2 2 0 0 2 2 1 1 ABC transporter KTI12 PF08433.10 KFP15690.1 - 0.0043 16.5 1.1 3.6 6.9 0.0 3.5 4 0 0 4 4 4 1 Chromatin associated protein KTI12 AAA_7 PF12775.7 KFP15690.1 - 0.0046 16.5 0.0 0.1 12.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFP15690.1 - 0.0063 16.3 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.22 KFP15690.1 - 0.0082 15.4 0.0 1 8.5 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 KFP15690.1 - 0.012 15.5 0.1 0.17 11.8 0.0 2.7 3 1 0 3 3 3 0 Rad17 P-loop domain AAA_11 PF13086.6 KFP15690.1 - 0.013 15.3 0.2 1.1 8.9 0.2 2.6 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KFP15690.1 - 0.015 14.4 0.0 2.1 7.3 0.0 2.7 3 0 0 3 3 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KFP15690.1 - 0.027 14.8 0.1 3.4 8.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 KFP15690.1 - 0.061 13.2 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 KFP15690.1 - 0.084 12.8 0.0 15 5.4 0.0 2.9 2 1 0 2 2 2 0 NTPase SKI PF01202.22 KFP15690.1 - 0.11 12.6 0.1 22 5.1 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase V-SNARE_C PF12352.8 KFP15691.1 - 1.6e-17 63.5 1.4 1.6e-17 63.5 1.4 2.5 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFP15691.1 - 3e-05 23.8 0.7 5.2e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.15 KFP15691.1 - 0.0007 19.9 1.9 0.0015 18.9 1.9 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus EzrA PF06160.12 KFP15691.1 - 0.0062 14.8 5.1 0.0078 14.4 5.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF2344 PF10105.9 KFP15691.1 - 0.025 14.4 0.3 0.034 14.0 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) EF-G-binding_N PF07299.11 KFP15691.1 - 0.042 14.4 2.4 0.067 13.7 0.6 2.2 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal HSCB_C PF07743.13 KFP15691.1 - 0.055 14.0 1.2 0.46 11.0 0.5 2.5 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Ran-binding PF05508.11 KFP15691.1 - 0.078 12.0 2.4 0.11 11.4 2.4 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF1690 PF07956.11 KFP15691.1 - 0.25 11.8 5.7 0.51 10.8 5.7 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) GIT_CC PF16559.5 KFP15691.1 - 0.68 9.8 4.2 2.8 7.9 0.0 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 KFP15691.1 - 1.5 8.9 7.0 1.4 8.9 0.3 2.2 1 1 1 2 2 2 0 FlxA-like protein zf-U11-48K PF05253.12 KFP15692.1 - 1.4e-21 75.9 11.3 4.6e-10 39.2 0.1 2.3 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger DUF716 PF04819.12 KFP15694.1 - 3.8e-35 120.5 12.3 7.1e-35 119.6 12.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF716) LNP1 PF15419.6 KFP15695.1 - 3.1e-68 229.5 22.6 3.5e-68 229.3 22.6 1.0 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 TPR_1 PF00515.28 KFP15696.1 - 3.1e-38 128.0 25.6 3.3e-09 36.2 0.8 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP15696.1 - 2.5e-32 108.3 26.8 1.5e-06 27.9 0.2 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFP15696.1 - 3.5e-28 95.4 21.0 0.00016 21.6 0.0 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KFP15696.1 - 5e-27 93.3 16.3 1e-06 28.3 1.2 7.8 6 2 2 8 8 8 6 TPR repeat TPR_14 PF13428.6 KFP15696.1 - 1.2e-20 72.4 7.9 0.0013 19.4 0.0 8.5 6 2 4 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP15696.1 - 8.9e-19 67.6 11.1 7.6e-06 26.1 0.1 6.9 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP15696.1 - 7.7e-17 60.4 21.4 0.0037 17.5 0.1 9.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP15696.1 - 3e-13 49.5 8.0 1.3 9.8 0.0 9.0 9 1 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP15696.1 - 3.6e-12 46.3 2.4 0.0012 19.0 0.3 6.9 3 3 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP15696.1 - 9.7e-09 35.6 20.1 0.041 14.4 0.1 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP15696.1 - 1.1e-08 35.6 5.0 2.1 9.0 0.0 6.8 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP15696.1 - 4.4e-08 32.6 3.2 0.04 14.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF5569 PF17729.1 KFP15696.1 - 2.7e-06 27.5 2.7 1.2e-05 25.3 0.2 2.6 2 1 1 3 3 3 1 Family of unknown function (DUF5569) MIT PF04212.18 KFP15696.1 - 0.00011 22.2 12.2 0.12 12.5 1.7 5.6 4 1 0 4 4 4 2 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 KFP15696.1 - 0.00072 19.7 0.7 0.0083 16.3 0.1 2.8 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 TPR_10 PF13374.6 KFP15696.1 - 0.0019 18.0 17.9 4.8 7.2 0.0 6.7 6 1 1 7 7 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP15696.1 - 0.0047 16.4 0.8 4.2 6.9 0.0 4.3 4 1 1 5 5 5 1 SHNi-TPR MP PF01107.18 KFP15696.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral movement protein (MP) TPR_MalT PF17874.1 KFP15696.1 - 0.011 15.2 3.3 0.077 12.3 0.1 3.2 3 3 0 3 3 3 0 MalT-like TPR region PPR PF01535.20 KFP15696.1 - 0.017 15.3 0.3 7.5 7.0 0.0 3.6 3 0 0 3 3 2 0 PPR repeat RPN7 PF10602.9 KFP15696.1 - 0.034 13.8 0.4 0.034 13.8 0.4 4.0 3 2 1 4 4 4 0 26S proteasome subunit RPN7 HrpB1_HrpK PF09613.10 KFP15696.1 - 0.035 13.8 1.2 7.1 6.3 0.1 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Hypoth_Ymh PF09509.10 KFP15696.1 - 0.062 13.2 3.2 6.4 6.7 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (Hypoth_ymh) Mad3_BUB1_I PF08311.12 KFP15696.1 - 0.22 11.5 10.8 0.59 10.1 0.2 4.7 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 KFP15696.1 - 4.5 7.6 24.9 7.7 6.8 0.2 5.8 4 3 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 CN_hydrolase PF00795.22 KFP15697.1 - 1.2e-65 221.5 0.0 1.3e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RabGAP-TBC PF00566.18 KFP15698.1 - 2.1e-20 73.3 1.0 3.9e-20 72.4 1.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 KFP15698.1 - 4.8e-08 33.5 0.0 1.3e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain CortBP2 PF09727.9 KFP15699.1 - 8.9e-64 214.9 28.1 8.9e-64 214.9 28.1 7.2 2 2 5 7 7 7 3 Cortactin-binding protein-2 SIKE PF05769.11 KFP15699.1 - 0.0017 18.3 13.5 0.0017 18.3 13.5 7.0 2 1 4 6 6 6 3 SIKE family Occludin_ELL PF07303.13 KFP15699.1 - 0.0045 17.7 10.6 0.0045 17.7 10.6 8.8 3 3 6 9 9 9 3 Occludin homology domain CMS1 PF14617.6 KFP15700.1 - 6.4e-31 107.6 1.7 1e-30 106.9 1.7 1.3 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFP15700.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Herpes_ori_bp PF02399.15 KFP15700.1 - 0.0046 15.1 0.2 0.0049 15.0 0.2 1.0 1 0 0 1 1 1 1 Origin of replication binding protein CDC50 PF03381.15 KFP15701.1 - 4.9e-86 288.7 1.9 6.4e-86 288.3 1.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CD20 PF04103.15 KFP15701.1 - 0.099 12.7 0.1 0.099 12.7 0.1 1.8 2 0 0 2 2 2 0 CD20-like family F5_F8_type_C PF00754.25 KFP15702.1 - 6.6e-26 90.9 1.7 7.4e-26 90.7 0.4 1.7 2 0 0 2 2 2 1 F5/8 type C domain CUB PF00431.20 KFP15702.1 - 8.3e-25 87.3 0.0 1.5e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain LCCL PF03815.19 KFP15702.1 - 9.2e-14 51.3 0.5 2.2e-13 50.1 0.2 1.8 2 0 0 2 2 2 1 LCCL domain Syndecan PF01034.20 KFP15702.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain DUF4448 PF14610.6 KFP15702.1 - 0.031 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glyco_transf_29 PF00777.18 KFP15706.1 - 1.2e-65 221.6 0.0 1.5e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Coprogen_oxidas PF01218.18 KFP15707.1 - 1.2e-128 428.0 0.0 1.4e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase 7tm_1 PF00001.21 KFP15709.1 - 3.9e-48 164.1 18.8 3.9e-48 164.1 18.8 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP15709.1 - 0.00083 19.1 19.7 0.00083 19.1 19.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.15 KFP15709.1 - 1.5 8.8 10.9 0.23 11.4 2.3 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa TIP41 PF04176.13 KFP15710.1 - 2.9e-67 225.5 0.5 3.4e-67 225.2 0.5 1.0 1 0 0 1 1 1 1 TIP41-like family DGF-1_4 PF11024.8 KFP15710.1 - 0.15 12.9 1.0 0.4 11.5 0.5 1.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Got1 PF04178.12 KFP15711.1 - 1.2e-38 132.0 15.8 5.1e-38 130.0 12.7 1.9 1 1 1 2 2 2 2 Got1/Sft2-like family Bac_export_2 PF01312.19 KFP15711.1 - 0.13 11.4 0.7 0.15 11.2 0.7 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF4064 PF13273.6 KFP15711.1 - 0.21 11.9 8.2 0.41 10.9 4.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PGG PF13962.6 KFP15711.1 - 0.76 9.6 6.0 0.17 11.7 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF5423 PF17461.2 KFP15711.1 - 1.3 7.8 5.8 0.83 8.4 3.9 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5423) DUF2244 PF10003.9 KFP15711.1 - 2.3 7.9 12.0 0.21 11.2 4.1 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF5090 PF17009.5 KFP15711.1 - 5.2 7.0 7.3 6.7 6.6 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) T-box PF00907.22 KFP15712.1 - 1.4e-69 234.1 0.0 1.8e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 T-box DERM PF14704.6 KFP15717.1 - 1.1e-31 110.4 3.5 1.3e-31 110.2 3.5 1.1 1 0 0 1 1 1 1 Dermatopontin NDK PF00334.19 KFP15718.1 - 4.8e-72 240.3 0.0 9.1e-41 139.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 KFP15718.1 - 6.5e-06 25.9 0.5 3.1e-05 23.7 0.2 2.1 2 0 0 2 2 2 1 DUF1126 PH-like domain DASH_Hsk3 PF08227.11 KFP15719.1 - 3.5e-10 40.1 1.4 1.1e-09 38.5 0.2 2.4 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like CC2-LZ PF16516.5 KFP15719.1 - 0.046 14.1 0.5 0.046 14.1 0.5 3.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PI3K_P85_iSH2 PF16454.5 KFP15719.1 - 3.5 7.2 16.0 0.19 11.3 3.9 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4207 PF13904.6 KFP15720.1 - 0.0034 17.1 35.3 0.0034 17.1 35.3 3.6 2 2 2 4 4 4 3 Domain of unknown function (DUF4207) Folate_carrier PF01770.18 KFP15721.1 - 2.5e-151 504.1 25.1 3e-151 503.8 25.1 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFP15721.1 - 7e-11 41.6 17.8 7e-11 41.6 17.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Autophagy_N PF03986.13 KFP15722.1 - 1.3e-46 158.0 1.0 1.3e-46 158.0 1.0 1.6 1 1 1 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KFP15722.1 - 1.5e-20 73.5 4.1 3.2e-20 72.5 4.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KFP15722.1 - 5.5e-16 57.8 0.7 1e-15 56.9 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.12 KFP15722.1 - 0.16 11.4 4.4 0.24 10.8 4.4 1.3 1 0 0 1 1 1 0 SDA1 Nuc_sug_transp PF04142.15 KFP15723.1 - 3.3e-50 171.1 10.7 4.9e-50 170.5 10.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFP15723.1 - 2.9e-06 27.5 5.5 2.9e-06 27.5 5.5 3.2 3 1 0 3 3 3 1 EamA-like transporter family HCMV_UL124 PF17609.2 KFP15723.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function DUF4174 PF13778.6 KFP15724.1 - 6.9e-106 349.3 0.1 1e-37 129.3 1.4 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4174) V-set PF07686.17 KFP15725.1 - 1.7e-06 28.1 0.0 4.5e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 KFP15725.1 - 1.8e-06 28.0 0.8 0.051 13.7 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP15725.1 - 6.3e-05 23.0 0.2 0.00013 21.9 0.2 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFP15725.1 - 0.00024 21.6 0.2 1.1 10.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP15725.1 - 0.0092 16.0 0.0 2.7 8.1 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP15726.1 - 5.7e-06 26.4 1.7 0.02 15.1 0.2 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP15726.1 - 8.6e-06 25.7 0.8 1.6e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP15726.1 - 1.4e-05 25.2 0.1 2.9e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP15726.1 - 0.00016 22.2 0.7 0.56 10.8 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP15726.1 - 0.00067 19.7 0.1 1.5 9.0 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain MMR_HSR1 PF01926.23 KFP15727.1 - 5.5e-20 71.6 0.0 6.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP15727.1 - 4.3e-08 32.9 0.0 6e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP15727.1 - 1.5e-06 27.9 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP15727.1 - 4.7e-06 26.6 0.0 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFP15727.1 - 0.00033 20.7 0.1 0.14 12.2 0.0 2.2 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 KFP15727.1 - 0.00038 19.9 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IIGP PF05049.13 KFP15727.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KFP15727.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFP15727.1 - 0.025 14.4 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KFP15727.1 - 0.047 13.9 0.0 0.069 13.4 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KFP15727.1 - 0.056 13.2 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KFP15727.1 - 0.058 12.7 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFP15727.1 - 0.12 12.1 0.0 1.2 8.9 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TFIID-18kDa PF02269.16 KFP15728.1 - 1.7e-38 130.5 0.4 2e-38 130.3 0.4 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GTP_EFTU_D2 PF03144.25 KFP15728.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu domain 2 KIND PF16474.5 KFP15729.1 - 1.5e-44 152.3 0.2 1.8e-32 112.8 0.0 2.1 1 1 1 2 2 2 2 Kinase non-catalytic C-lobe domain Ig_3 PF13927.6 KFP15730.1 - 2e-43 146.9 5.0 2.1e-14 53.9 0.0 5.5 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFP15730.1 - 3.8e-38 129.4 0.0 2.5e-13 49.9 0.0 5.1 6 0 0 6 6 6 4 Immunoglobulin I-set domain fn3 PF00041.21 KFP15730.1 - 5.1e-36 122.9 1.0 3.4e-13 49.7 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.6 KFP15730.1 - 2.5e-31 107.8 0.3 3.5e-11 43.3 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFP15730.1 - 9.1e-25 86.7 0.1 6.8e-09 35.8 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain ISET-FN3_linker PF16625.5 KFP15730.1 - 2.6e-22 79.1 8.9 2.6e-22 79.1 8.9 3.6 4 0 0 4 4 2 1 Unstructured linking region I-set and fnIII on Brother of CDO C2-set_2 PF08205.12 KFP15730.1 - 1.3e-10 41.2 1.2 0.014 15.5 0.0 4.4 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP15730.1 - 2.2e-10 40.7 4.2 0.012 15.7 0.1 6.8 5 2 0 5 5 5 2 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP15730.1 - 6.3e-10 39.5 0.1 0.028 15.0 0.0 4.1 4 0 0 4 4 3 2 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.5 KFP15730.1 - 5.8e-06 26.5 0.0 0.027 14.7 0.0 3.6 4 0 0 4 4 3 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFP15730.1 - 5.9e-06 26.6 0.5 0.57 10.6 0.0 4.2 4 1 0 4 4 3 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFP15730.1 - 6.4e-05 23.3 0.0 0.065 13.7 0.0 3.8 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain BiPBP_C PF06832.12 KFP15730.1 - 0.00028 20.9 0.1 1.1 9.3 0.0 3.7 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 KFP15730.1 - 0.0073 15.9 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain TNFR_16_TM PF18422.1 KFP15730.1 - 0.02 14.8 3.3 0.42 10.6 1.2 2.4 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Izumo-Ig PF16706.5 KFP15730.1 - 0.023 14.8 0.0 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP15730.1 - 0.028 14.5 0.1 8.6 6.5 0.0 3.6 4 0 0 4 4 4 0 C17orf99 Ig domain Interfer-bind PF09294.10 KFP15730.1 - 0.063 13.6 0.2 2.2 8.6 0.0 3.1 4 0 0 4 4 3 0 Interferon-alpha/beta receptor, fibronectin type III Na_Ca_ex PF01699.24 KFP15730.1 - 0.18 11.8 0.3 0.32 10.9 0.3 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein UPF0147 PF03685.13 KFP15731.1 - 0.26 11.4 3.5 0.45 10.6 0.9 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) Vac_Fusion PF02346.16 KFP15731.1 - 0.26 10.9 3.5 2.2 8.0 0.1 3.1 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Glyco_transf_90 PF05686.12 KFP15732.1 - 2.8e-112 375.5 1.4 3.7e-112 375.1 1.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 KFP15732.1 - 1.9e-07 31.8 0.0 3.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.6 KFP15732.1 - 2.3e-05 24.7 0.0 4.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 XPG_N PF00752.17 KFP15733.1 - 1.5e-32 112.0 0.0 4.4e-32 110.5 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFP15733.1 - 3.7e-25 88.1 0.0 2.5e-24 85.5 0.0 2.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KFP15733.1 - 0.0012 19.4 0.0 0.0089 16.6 0.0 2.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Methyltransf_16 PF10294.9 KFP15734.1 - 4.2e-33 114.5 0.0 4.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP15734.1 - 1.5e-07 31.4 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP15734.1 - 0.00058 19.3 0.0 0.00072 19.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFP15734.1 - 0.021 15.6 0.1 0.047 14.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFP15734.1 - 0.05 14.3 0.0 0.094 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RVT_1 PF00078.27 KFP15740.1 - 1.4e-18 67.3 0.0 2.2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP15740.1 - 0.014 15.5 0.1 0.036 14.1 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 KFP15742.1 - 1e-105 352.7 0.0 1.3e-105 352.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP15742.1 - 1.1e-41 142.9 0.0 8.9e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.16 KFP15742.1 - 8.9e-33 112.2 1.9 1.3e-19 70.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP15742.1 - 3.5e-28 98.0 7.7 1.6e-14 54.2 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP15742.1 - 2e-23 82.4 4.5 5e-11 42.6 0.8 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP15742.1 - 9.5e-22 77.1 3.8 3.2e-10 40.2 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain VEGFR-2_TMD PF17988.1 KFP15742.1 - 3.4e-18 64.8 0.7 7.7e-18 63.6 0.7 1.6 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain V-set PF07686.17 KFP15742.1 - 3.2e-11 43.4 8.1 0.0011 19.1 1.5 5.1 3 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP15742.1 - 5.8e-09 36.1 2.8 0.0005 20.3 0.0 3.6 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP15742.1 - 6e-09 36.2 3.4 0.00088 19.6 0.1 3.6 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP15742.1 - 6e-05 23.0 0.4 0.31 11.1 0.0 3.4 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP15742.1 - 0.00051 19.6 0.0 4.6 6.9 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFP15742.1 - 0.0018 18.0 1.6 0.2 11.4 0.2 3.3 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Haspin_kinase PF12330.8 KFP15742.1 - 0.0053 15.7 0.1 0.022 13.7 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain C2-set_2 PF08205.12 KFP15742.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFP15742.1 - 0.05 13.6 0.2 26 4.9 0.0 3.5 3 0 0 3 3 3 0 C17orf99 Ig domain ADH_N PF08240.12 KFP15742.1 - 0.054 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Erf4 PF10256.9 KFP15743.1 - 2.5e-10 40.5 0.0 3.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family GAGA_bind PF06217.12 KFP15743.1 - 2.3 8.4 4.8 3 8.1 4.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PDZ PF00595.24 KFP15744.1 - 3.3e-62 206.8 3.8 3.4e-16 59.4 0.1 4.2 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP15744.1 - 6.3e-33 112.4 1.1 6.7e-08 32.3 0.1 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP15744.1 - 4.8e-18 65.3 0.5 0.007 16.7 0.0 4.5 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.25 KFP15744.1 - 2.6e-07 30.4 8.6 6.9e-07 29.0 8.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP15744.1 - 5.3e-07 29.5 7.1 1.3e-06 28.3 7.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP15744.1 - 1.3e-06 28.1 3.5 4e-06 26.6 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP15744.1 - 1.4e-06 28.0 9.7 1.4e-06 28.0 9.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP15744.1 - 1e-05 25.8 6.7 1e-05 25.8 6.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP15744.1 - 2e-05 24.6 9.4 6.6e-05 23.0 9.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP15744.1 - 3.7e-05 23.6 6.6 3.7e-05 23.6 6.6 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Tricorn_PDZ PF14685.6 KFP15744.1 - 0.0003 20.7 0.2 21 5.1 0.0 4.2 4 0 0 4 4 4 0 Tricorn protease PDZ domain U-box PF04564.15 KFP15744.1 - 0.00091 19.4 0.1 0.026 14.7 0.1 2.8 1 1 1 2 2 2 1 U-box domain zf-rbx1 PF12678.7 KFP15744.1 - 0.0036 17.5 4.8 0.013 15.8 4.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP15744.1 - 0.13 12.2 8.1 0.38 10.6 8.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ras PF00071.22 KFP15745.1 - 3.9e-23 81.8 0.0 1.6e-22 79.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KFP15745.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family UCH PF00443.29 KFP15746.1 - 1.7e-59 201.4 2.6 2.1e-59 201.2 2.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP15746.1 - 6.8e-31 108.0 3.9 9e-31 107.6 3.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFP15746.1 - 0.00017 21.2 11.1 0.0016 18.0 8.8 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase NapB PF03892.14 KFP15746.1 - 0.14 12.1 2.4 0.36 10.8 2.4 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) CEBP_ZZ PF16366.5 KFP15746.1 - 1.3 9.3 6.9 0.56 10.5 1.3 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain WH2 PF02205.20 KFP15747.1 - 5.3e-08 32.4 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 WH2 motif zf-RING_2 PF13639.6 KFP15748.1 - 3.5e-13 49.7 8.0 5.5e-13 49.0 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP15748.1 - 3.5e-10 40.0 4.8 7e-10 39.0 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP15748.1 - 1.6e-08 34.1 3.4 1.6e-08 34.1 3.4 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP15748.1 - 4.8e-08 32.7 6.2 7.4e-08 32.1 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP15748.1 - 1.9e-06 27.6 7.6 3.1e-06 26.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP15748.1 - 4.3e-05 23.4 6.3 6.8e-05 22.8 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KFP15748.1 - 4.6e-05 23.4 1.4 9.5e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFP15748.1 - 0.00056 19.7 4.7 0.00095 19.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP15748.1 - 0.0017 18.2 4.5 0.003 17.4 4.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP15748.1 - 0.0048 16.9 4.0 0.01 15.8 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFP15748.1 - 0.15 11.7 5.1 0.23 11.1 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 KFP15748.1 - 0.16 12.2 1.2 0.3 11.3 1.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KFP15748.1 - 0.17 11.7 4.5 0.32 10.8 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KFP15748.1 - 0.25 11.7 6.2 0.4 11.0 6.2 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFP15748.1 - 1.1 9.4 7.4 2.3 8.4 7.4 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFP15748.1 - 1.9 8.7 5.0 6.8 6.9 5.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain GREB1 PF15782.5 KFP15748.1 - 4.2 4.3 11.4 5.7 3.9 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPRTase PF14681.6 KFP15749.1 - 4.1e-30 104.8 0.0 5.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFP15749.1 - 6.9e-05 22.4 0.0 7.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4683 PF15735.5 KFP15750.1 - 7.3e-125 417.7 7.9 7.3e-125 417.7 7.9 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4683) ABC_membrane PF00664.23 KFP15751.1 - 4e-37 128.3 9.7 5.2e-37 128.0 9.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP15751.1 - 4.8e-34 117.8 0.0 1.1e-33 116.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP15751.1 - 1e-05 25.1 0.1 0.004 16.6 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFP15751.1 - 0.00091 19.6 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 KFP15751.1 - 0.0075 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 KFP15751.1 - 0.011 15.5 0.2 0.011 15.5 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFP15751.1 - 0.012 15.9 0.3 0.2 11.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP15751.1 - 0.04 14.2 0.0 0.27 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KFP15751.1 - 0.057 12.6 0.0 0.13 11.4 0.0 1.7 1 1 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 KFP15751.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP15751.1 - 0.13 11.8 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KFP15751.1 - 0.14 12.3 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KFP15751.1 - 0.15 11.7 0.1 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFP15751.1 - 0.18 12.4 0.7 0.85 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Hormone_recep PF00104.30 KFP15752.1 - 1.1e-13 51.2 0.3 2.3e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP15753.1 - 3.8e-34 117.0 16.3 4.4e-34 116.8 16.3 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Class_IIIsignal PF04021.12 KFP15754.1 - 0.65 10.1 0.2 0.65 10.1 0.2 2.1 2 0 0 2 2 2 0 Class III signal peptide zf-C4 PF00105.18 KFP15756.1 - 2.2e-30 104.9 15.9 4.1e-30 104.0 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP15756.1 - 6.2e-17 61.9 0.0 2.4e-16 59.9 0.0 1.9 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP15757.1 - 2.8e-31 107.8 15.9 7.1e-31 106.5 15.9 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP15757.1 - 4.3e-25 88.5 0.3 1e-24 87.2 0.3 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor LpxD PF04613.14 KFP15757.1 - 0.038 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Ribosomal_L15e PF00827.17 KFP15759.1 - 4.7e-98 326.5 3.7 5.4e-98 326.3 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hepatitis_core PF00906.20 KFP15759.1 - 2 7.9 7.6 0.14 11.7 0.3 2.0 2 0 0 2 2 2 0 Hepatitis core antigen Ras PF00071.22 KFP15760.1 - 3.4e-26 91.8 0.4 3.9e-26 91.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15760.1 - 1.3e-11 44.8 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP15760.1 - 7.6e-09 35.3 0.3 1e-08 34.9 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP15760.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP15760.1 - 0.00068 19.6 0.5 0.046 13.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP15760.1 - 0.0019 17.8 1.4 0.34 10.4 1.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFP15760.1 - 0.0072 16.4 0.6 0.46 10.5 0.0 2.7 2 1 1 3 3 3 1 Dynamin family cobW PF02492.19 KFP15760.1 - 0.038 13.6 2.9 1.4 8.5 0.4 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KFP15760.1 - 0.048 13.7 0.1 0.21 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP15760.1 - 0.07 12.7 0.1 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 KFP15760.1 - 0.076 12.7 0.1 0.1 12.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain PRORP PF16953.5 KFP15760.1 - 0.086 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P AAA_16 PF13191.6 KFP15760.1 - 0.13 12.6 0.6 0.37 11.1 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFP15760.1 - 0.17 12.2 0.7 1.2 9.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain UQ_con PF00179.26 KFP15761.1 - 2.1e-43 147.3 0.0 2.3e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP15761.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFP15761.1 - 0.0098 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFP15761.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.26 KFP15762.1 - 1.4e-43 147.9 0.0 1.5e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP15762.1 - 0.00064 19.4 0.0 0.00079 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFP15762.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KFP15762.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain zf-met PF12874.7 KFP15764.1 - 2e-08 34.3 0.7 3.4e-08 33.6 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP15764.1 - 0.00014 22.0 0.7 0.00025 21.2 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP15765.1 - 2e-08 34.3 0.7 3.4e-08 33.6 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP15765.1 - 0.00014 22.0 0.7 0.00025 21.2 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding PCAF_N PF06466.11 KFP15767.1 - 8.7e-104 346.5 1.1 1.4e-103 345.9 1.1 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KFP15767.1 - 3.6e-25 87.8 0.4 8.5e-25 86.6 0.4 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFP15767.1 - 3.7e-10 40.1 0.0 8.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP15767.1 - 1.6e-07 31.3 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP15767.1 - 6.7e-06 26.4 0.2 1.4e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP15767.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 KFP15770.1 - 1.2e-29 103.7 0.6 2.5e-24 86.3 0.0 3.4 3 1 1 4 4 4 2 Protein phosphatase 2C Ras PF00071.22 KFP15771.1 - 3.1e-63 212.2 0.3 3.6e-63 212.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP15771.1 - 7.4e-36 123.0 0.1 1.5e-35 122.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP15771.1 - 1e-12 47.9 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP15771.1 - 2.2e-05 24.0 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP15771.1 - 5.3e-05 23.3 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP15771.1 - 0.0004 20.3 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP15771.1 - 0.0018 17.9 0.0 0.0052 16.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP15771.1 - 0.013 15.9 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MCR_beta PF02241.18 KFP15771.1 - 0.017 14.7 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain BrnT_toxin PF04365.13 KFP15771.1 - 0.06 13.7 0.1 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system EF-hand_7 PF13499.6 KFP15772.1 - 2e-10 40.9 5.5 2.2e-10 40.8 3.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP15772.1 - 2e-09 36.3 4.4 0.00082 18.7 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP15772.1 - 1e-08 34.4 2.8 0.00051 19.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP15772.1 - 3.2e-05 23.7 4.9 0.00053 19.8 4.0 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP15772.1 - 8e-05 22.0 2.2 0.26 10.9 0.2 2.8 3 0 0 3 3 3 2 EF hand DUF5580 PF17743.1 KFP15772.1 - 0.00015 20.4 0.4 0.00023 19.9 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF4483 PF14825.6 KFP15772.1 - 0.00036 20.3 0.1 0.31 10.8 0.0 3.4 2 1 0 3 3 3 1 Domain of unknown function (DUF4483) SPARC_Ca_bdg PF10591.9 KFP15772.1 - 0.009 16.3 1.1 0.02 15.2 1.1 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFP15772.1 - 0.31 10.9 2.8 4.9 7.1 0.5 2.6 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 KFP15772.1 - 0.34 10.9 1.6 1.7 8.7 0.6 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ion_trans PF00520.31 KFP15773.1 - 6.7e-33 113.9 13.2 9.9e-33 113.4 13.2 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFP15773.1 - 3.4e-18 65.8 0.0 1.5e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain Ion_trans_2 PF07885.16 KFP15773.1 - 8.5e-11 41.7 0.6 8.5e-11 41.7 0.6 2.9 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 KFP15773.1 - 1.3e-09 38.0 0.0 3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_3 PF08447.12 KFP15773.1 - 1.3e-07 31.8 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KFP15773.1 - 1.7e-05 24.8 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFP15773.1 - 0.00015 22.0 0.0 0.00073 19.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold CENP-F_leu_zip PF10473.9 KFP15773.1 - 0.0016 18.5 1.6 0.28 11.2 0.8 2.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2959 PF11172.8 KFP15773.1 - 0.057 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) LPP PF04728.13 KFP15773.1 - 0.1 13.0 0.4 0.32 11.4 0.4 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SlyX PF04102.12 KFP15773.1 - 0.12 13.0 0.4 0.42 11.3 0.4 1.9 1 0 0 1 1 1 0 SlyX Seryl_tRNA_N PF02403.22 KFP15773.1 - 0.13 12.5 1.0 0.37 11.0 1.0 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KFP15773.1 - 0.16 12.1 0.8 0.42 10.7 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PI-PLC-X PF00388.19 KFP15780.1 - 2.6e-61 205.4 0.1 5.7e-61 204.4 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP15780.1 - 7.2e-39 132.7 0.2 2.1e-38 131.2 0.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFP15780.1 - 1.2e-21 77.6 0.2 8.3e-21 74.9 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_like PF09279.11 KFP15780.1 - 2.5e-17 63.1 0.1 5.6e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP15780.1 - 1.1e-16 61.0 0.0 2.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH_14 PF17787.1 KFP15780.1 - 1.8e-06 27.8 0.1 4.9e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 PH domain PH PF00169.29 KFP15780.1 - 2.5e-05 24.7 0.1 8.2e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 KFP15780.1 - 0.00031 20.8 0.0 0.00076 19.6 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology RRM_1 PF00076.22 KFP15781.1 - 2.8e-14 52.7 0.4 4.4e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP15781.1 - 0.00092 19.3 0.4 0.004 17.2 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KFP15781.1 - 0.0069 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Raftlin PF15250.6 KFP15782.1 - 1.2e-220 733.2 0.4 1.5e-220 732.9 0.4 1.1 1 0 0 1 1 1 1 Raftlin PilO PF04350.13 KFP15782.1 - 0.041 14.0 2.4 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Pilus assembly protein, PilO NAD_binding_1 PF00175.21 KFP15783.1 - 1.1e-13 51.7 0.0 2.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFP15783.1 - 3.2e-07 30.6 0.0 6.6e-06 26.3 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF1707 PF08044.11 KFP15783.1 - 0.021 14.9 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Ank_2 PF12796.7 KFP15785.1 - 6e-163 529.9 47.3 7.4e-18 64.9 0.1 14.2 3 3 13 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP15785.1 - 8.3e-153 495.0 48.0 4e-15 56.0 0.9 20.7 9 5 12 21 21 21 21 Ankyrin repeats (many copies) Ank PF00023.30 KFP15785.1 - 6.9e-143 459.5 74.4 6.6e-07 29.5 0.1 27.9 28 0 0 28 28 28 26 Ankyrin repeat Ank_3 PF13606.6 KFP15785.1 - 8.9e-119 372.9 52.1 6.5e-06 26.1 0.1 28.2 28 0 0 28 28 28 27 Ankyrin repeat Ank_5 PF13857.6 KFP15785.1 - 1.6e-116 378.8 58.6 8.7e-10 38.7 0.2 21.3 5 4 19 24 24 24 22 Ankyrin repeats (many copies) CN_hydrolase PF00795.22 KFP15786.1 - 1.9e-17 63.5 0.0 2.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPP_enzyme_N PF02776.18 KFP15787.1 - 7.1e-40 136.4 0.2 5.3e-38 130.3 0.1 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFP15787.1 - 1.8e-34 118.4 0.0 6.7e-34 116.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFP15787.1 - 4.6e-29 101.2 0.1 1.4e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 KFP15787.1 - 0.051 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Collagen PF01391.18 KFP15788.1 - 7.5e-29 99.3 98.5 7.1e-10 38.5 28.1 4.5 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) DUF4215 PF13948.6 KFP15788.1 - 6.5e-05 23.3 13.2 0.00011 22.6 5.6 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4215) GLTP PF08718.11 KFP15789.1 - 8.7e-43 146.1 0.0 2e-42 145.0 0.0 1.6 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH PF00169.29 KFP15789.1 - 3e-08 34.1 0.0 9.1e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP15789.1 - 6.7e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP15789.1 - 0.017 15.5 0.0 0.18 12.2 0.0 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain FKBP_C PF00254.28 KFP15790.1 - 1.4e-28 99.1 0.0 2.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 KFP15790.1 - 1.4e-07 31.9 2.7 2.5e-07 31.1 2.7 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP15790.1 - 4.3e-07 29.4 3.4 0.023 14.6 0.9 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP15790.1 - 1.7e-06 27.3 2.7 0.0041 16.6 1.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KFP15790.1 - 4.2e-05 22.8 8.3 0.0015 17.9 1.6 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFP15790.1 - 0.12 12.3 2.0 1.4 8.8 0.5 2.3 2 0 0 2 2 2 0 EF-hand domain pair WH2 PF02205.20 KFP15791.1 - 8.5e-10 38.1 0.8 2.7e-09 36.6 0.8 1.9 1 0 0 1 1 1 1 WH2 motif RhoGAP PF00620.27 KFP15793.1 - 2.1e-50 170.5 0.0 4.6e-50 169.4 0.0 1.5 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 KFP15793.1 - 1.5e-16 60.0 7.0 2.6e-16 59.3 7.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 KFP15793.1 - 5.6e-12 45.6 0.1 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 SH2 domain zf-RING-like PF08746.11 KFP15793.1 - 0.061 13.6 5.0 0.14 12.5 5.0 1.6 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.6 KFP15793.1 - 0.12 12.0 2.3 0.26 10.9 2.3 1.5 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KFP15793.1 - 0.22 11.9 3.0 0.54 10.6 3.0 1.7 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 KFP15793.1 - 1.8 8.8 9.2 1.6 9.0 7.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 KFP15793.1 - 7 6.6 9.1 15 5.6 9.1 1.5 1 0 0 1 1 1 0 PHD-finger bZIP_1 PF00170.21 KFP15796.1 - 7e-13 48.5 8.5 1.2e-12 47.7 8.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP15796.1 - 3.2e-10 39.9 7.9 3.2e-10 39.9 7.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP15796.1 - 4.1e-05 24.0 5.1 0.00013 22.5 5.1 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 KFP15796.1 - 0.0085 16.5 2.7 0.0085 16.5 2.7 1.7 2 0 0 2 2 2 1 Cell division protein ZapB TolA_bind_tri PF16331.5 KFP15796.1 - 0.021 14.9 3.1 0.021 14.9 3.1 2.5 3 0 0 3 3 3 0 TolA binding protein trimerisation NDUFB11 PF17250.2 KFP15796.1 - 0.14 12.8 2.5 0.12 13.0 0.9 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit GIT_CC PF16559.5 KFP15796.1 - 0.15 12.0 5.0 0.43 10.5 5.0 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KFP15796.1 - 0.44 10.3 3.1 0.87 9.4 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Zip PF02535.22 KFP15796.1 - 0.75 9.0 9.5 1.1 8.4 9.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Cnn_1N PF07989.11 KFP15796.1 - 3.2 8.0 7.6 0.23 11.7 2.5 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-C2H2_aberr PF17017.5 KFP15797.1 - 8.6e-07 29.3 2.7 6.2e-05 23.2 0.2 2.2 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KFP15797.1 - 0.0017 19.0 6.3 0.54 11.3 2.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP15797.1 - 0.012 16.0 6.8 0.68 10.5 2.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFP15797.1 - 0.16 11.6 0.1 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain ARS2 PF04959.13 KFP15797.1 - 0.17 12.2 4.1 9.5 6.5 0.4 2.8 1 1 1 3 3 3 0 Arsenite-resistance protein 2 NAD_binding_2 PF03446.15 KFP15799.1 - 1.4e-50 171.6 0.2 2e-50 171.0 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFP15799.1 - 1e-33 116.2 0.0 1.5e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KFP15799.1 - 5.6e-10 38.9 0.0 9.3e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFP15799.1 - 1.6e-07 31.8 0.0 4.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFP15799.1 - 0.00027 20.9 0.0 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KFP15799.1 - 0.0038 16.3 0.1 0.005 15.9 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase IlvN PF07991.12 KFP15799.1 - 0.0067 16.0 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KFP15799.1 - 0.0098 16.1 0.0 0.035 14.4 0.0 2.1 2 1 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFP15799.1 - 0.067 12.8 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Homeodomain PF00046.29 KFP15802.1 - 1.9e-19 69.3 8.0 2.2e-19 69.0 8.0 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15802.1 - 5.8e-05 22.9 2.5 8.4e-05 22.4 2.5 1.4 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP15802.1 - 0.036 14.2 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) CI-B14_5a PF07347.12 KFP15802.1 - 0.037 13.9 0.8 0.042 13.7 0.2 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homez PF11569.8 KFP15802.1 - 0.096 12.2 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3528 PF12045.8 KFP15803.1 - 2.1e-64 216.4 1.2 2.8e-64 216.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFP15803.1 - 4.6e-20 71.2 7.7 7.4e-20 70.5 7.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15803.1 - 0.039 13.9 0.8 0.074 13.0 0.8 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 KFP15803.1 - 0.13 11.7 0.1 0.33 10.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MerR_1 PF13411.6 KFP15803.1 - 0.19 11.9 0.9 0.62 10.2 0.2 2.0 1 1 1 2 2 2 0 MerR HTH family regulatory protein Homeodomain PF00046.29 KFP15804.1 - 1.6e-20 72.7 6.3 3.1e-20 71.8 6.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15804.1 - 0.028 14.3 0.3 0.069 13.1 0.3 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFP15805.1 - 8.1e-22 76.8 8.5 1.3e-21 76.2 8.5 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFP15805.1 - 0.18 12.1 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFP15806.1 - 1.7e-21 75.8 9.1 1.7e-21 75.8 9.1 1.7 2 0 0 2 2 2 1 Homeodomain DUF4074 PF13293.6 KFP15807.1 - 3.5e-37 126.5 8.8 3.5e-37 126.5 8.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4074) Homeodomain PF00046.29 KFP15807.1 - 1.5e-21 76.0 5.2 3.1e-21 75.0 5.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFP15808.1 - 8.4e-23 80.0 7.4 1e-22 79.7 7.4 1.1 1 0 0 1 1 1 1 Homeodomain YcgR PF07317.12 KFP15808.1 - 0.008 16.0 0.2 0.26 11.2 0.0 2.1 1 1 1 2 2 2 2 Flagellar regulator YcgR Homeobox_KN PF05920.11 KFP15808.1 - 0.029 14.3 3.3 0.051 13.5 0.4 2.2 2 0 0 2 2 2 0 Homeobox KN domain PH PF00169.29 KFP15810.1 - 7e-17 61.9 0.9 1.2e-16 61.1 0.9 1.4 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFP15810.1 - 2.2e-11 43.2 0.3 6.6e-11 41.6 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP15810.1 - 2.6e-10 39.8 0.1 6e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP15810.1 - 4.4e-10 39.3 0.1 9.7e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KFP15810.1 - 5.1e-06 26.8 3.8 1.6e-05 25.2 3.8 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFP15810.1 - 9.1e-06 26.0 0.5 2.4e-05 24.7 0.5 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFP15810.1 - 1.6e-05 24.9 0.1 3.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFP15810.1 - 0.044 13.6 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PX PF00787.24 KFP15812.1 - 2.5e-24 85.4 2.9 3.3e-24 85.1 2.9 1.2 1 0 0 1 1 1 1 PX domain Chromo_shadow PF01393.19 KFP15817.1 - 3.4e-33 113.5 0.1 1.4e-29 101.9 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFP15817.1 - 1.4e-20 72.9 0.1 1.1e-16 60.5 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFP15817.1 - 0.0092 16.1 0.1 0.053 13.7 0.1 2.1 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 RRM_1 PF00076.22 KFP15818.1 - 1.2e-32 111.5 0.0 4.8e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP15818.1 - 8.2e-09 35.5 0.1 0.00068 19.7 0.0 2.6 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KFP15818.1 - 0.033 13.9 0.5 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain FARP PF01581.16 KFP15822.1 - 0.05 14.1 0.9 83 4.4 0.0 3.8 3 0 0 3 3 3 0 FMRFamide related peptide family NPFF PF15085.6 KFP15822.1 - 0.49 10.8 2.2 15 6.0 0.1 3.1 2 2 0 2 2 2 0 Neuropeptide FF Cytochrom_C PF00034.21 KFP15824.1 - 7.5e-14 52.7 0.1 9.7e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFP15824.1 - 1.8e-06 28.2 2.6 8.9e-06 25.9 2.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFP15824.1 - 8.3e-05 22.3 3.1 0.00098 18.8 3.1 2.3 1 1 0 1 1 1 1 Cytochrome c-550 domain UPF0128 PF03673.13 KFP15824.1 - 0.071 12.6 0.1 0.096 12.2 0.1 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0128) Oxysterol_BP PF01237.18 KFP15825.1 - 2.6e-129 431.3 2.8 2.6e-129 431.3 2.8 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KFP15825.1 - 5.8e-12 45.7 0.1 1.5e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP15825.1 - 2.3e-07 31.3 1.4 9e-07 29.4 1.4 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP15825.1 - 3.6 8.0 5.9 13 6.3 0.1 3.0 1 1 1 2 2 2 0 Pleckstrin homology domain Striatin PF08232.12 KFP15825.1 - 4.4 7.9 7.5 15 6.1 1.6 2.7 2 0 0 2 2 2 0 Striatin family Gasdermin PF04598.12 KFP15826.1 - 1.9e-90 302.6 1.0 2.7e-90 302.1 1.0 1.2 1 0 0 1 1 1 1 Gasdermin pore forming domain Gasdermin_C PF17708.1 KFP15826.1 - 1.5e-45 155.5 8.8 1.5e-45 155.5 8.8 1.7 2 0 0 2 2 2 1 Gasdermin PUB domain Guanylate_kin PF00625.21 KFP15827.1 - 6.2e-49 166.2 0.0 1.2e-48 165.3 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFP15827.1 - 4.9e-29 99.8 1.0 4e-17 61.7 0.1 3.2 3 0 0 3 3 3 2 L27 domain SH3_2 PF07653.17 KFP15827.1 - 1.2e-11 44.1 0.3 4e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.24 KFP15827.1 - 8.8e-11 42.0 0.9 1.9e-10 40.9 0.9 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KFP15827.1 - 4.3e-06 26.2 0.1 1.1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 KFP15827.1 - 3.5e-05 23.6 0.1 8.5e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFP15827.1 - 5e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KFP15827.1 - 0.00017 21.9 0.1 0.00043 20.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KFP15827.1 - 0.00065 19.6 0.1 0.013 15.4 0.1 2.8 2 1 0 2 2 2 1 Tricorn protease PDZ domain Hormone_3 PF00159.18 KFP15830.1 - 5.5e-19 68.0 1.1 9.2e-19 67.2 1.1 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide FAM221 PF14753.6 KFP15831.1 - 2.5e-94 314.4 7.5 3.1e-94 314.1 7.5 1.1 1 0 0 1 1 1 1 Protein FAM221A/B DUF4525 PF15027.6 KFP15832.1 - 1.1e-76 255.1 0.4 1.4e-76 254.8 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF4407 PF14362.6 KFP15832.1 - 0.0014 18.0 0.5 0.062 12.7 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KFP15833.1 - 7.7e-20 70.5 0.0 1.1e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP15833.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Apt1 PF10351.9 KFP15833.1 - 0.29 9.9 11.8 0.31 9.8 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KFP15833.1 - 1.2 7.9 5.3 1.4 7.6 5.3 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 KFP15833.1 - 1.6 7.5 6.3 1.8 7.2 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 KH_1 PF00013.29 KFP15834.1 - 9.1e-59 195.2 13.3 3.3e-15 55.7 0.1 5.0 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 KFP15834.1 - 2.9e-17 62.2 0.0 6.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 KFP15834.1 - 5.8e-16 58.1 5.8 0.0034 17.2 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFP15834.1 - 7.9e-15 54.5 0.5 0.0024 17.7 0.0 4.7 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 KFP15834.1 - 6e-07 29.5 5.9 0.61 10.2 0.1 4.3 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 KFP15834.1 - 1.3e-05 25.1 0.1 0.14 12.1 0.0 4.3 5 0 0 5 5 5 1 KH-like RNA-binding domain RRM_5 PF13893.6 KFP15834.1 - 4.1e-05 23.2 0.0 0.023 14.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4041 PF13250.6 KFP15834.1 - 0.26 11.2 1.2 0.52 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) RsfS PF02410.15 KFP15836.1 - 1.9e-27 95.6 0.0 2.3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PKD PF00801.20 KFP15837.1 - 9.2e-12 44.6 1.2 6.2e-11 42.0 0.1 2.8 3 0 0 3 3 3 1 PKD domain Kelch_1 PF01344.25 KFP15839.1 - 8.1e-46 153.4 13.7 9.9e-13 47.5 0.5 5.8 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP15839.1 - 3e-34 117.2 1.0 3e-33 114.0 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP15839.1 - 9.5e-29 98.7 7.0 4.8e-09 36.2 0.0 6.3 2 1 4 6 6 6 5 Kelch motif BTB PF00651.31 KFP15839.1 - 1.2e-28 99.5 1.2 1.2e-28 99.5 1.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFP15839.1 - 2.1e-22 78.9 0.1 1.4e-08 34.6 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP15839.1 - 2.7e-21 74.7 6.2 3.4e-06 26.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KFP15839.1 - 6.7e-11 42.2 4.8 0.00041 20.6 0.0 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP15839.1 - 3e-09 36.6 3.3 0.12 12.4 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.11 KFP15839.1 - 0.038 13.2 1.5 0.2 10.8 0.3 2.5 2 1 1 3 3 3 0 Glyoxal oxidase N-terminus UvrD-helicase PF00580.21 KFP15839.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ADPRTs_Tse2 PF18648.1 KFP15839.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Hyccin PF09790.9 KFP15840.1 - 9.8e-130 432.3 0.6 1.6e-129 431.7 0.6 1.3 1 0 0 1 1 1 1 Hyccin IL6 PF00489.17 KFP15842.1 - 2.2e-29 102.4 1.0 2.5e-29 102.2 1.0 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family IL11 PF07400.11 KFP15842.1 - 0.0016 18.1 0.1 0.0019 17.9 0.1 1.0 1 0 0 1 1 1 1 Interleukin 11 COG2 PF06148.11 KFP15842.1 - 0.096 12.8 0.0 0.65 10.1 0.0 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-4CXXC_R1 PF10497.9 KFP15845.1 - 2.6e-37 127.0 8.9 4.5e-37 126.3 8.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-H2C2_2 PF13465.6 KFP15849.1 - 1.1e-15 57.3 8.8 4.2e-09 36.4 2.5 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP15849.1 - 3.1e-13 49.4 30.9 3.5e-06 27.1 1.1 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15849.1 - 1.1e-08 35.2 28.9 7e-05 23.3 2.8 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP15849.1 - 0.00015 21.6 16.8 0.0089 16.0 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP15849.1 - 0.0016 18.7 4.0 0.43 10.9 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP15849.1 - 0.005 17.1 6.5 0.011 16.1 4.2 2.2 2 1 0 2 2 2 1 C2H2-type zinc ribbon DUF971 PF06155.12 KFP15849.1 - 0.1 13.2 2.0 3.9 8.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF971) zf-LYAR PF08790.11 KFP15849.1 - 0.24 11.3 3.6 6.8 6.7 0.3 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 KFP15849.1 - 0.92 9.2 3.6 8.3 6.1 0.0 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFP15849.1 - 1.9 8.3 16.9 2.2 8.1 2.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 KFP15849.1 - 2 8.9 6.2 7.7 7.1 1.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.13 KFP15849.1 - 3.1 7.6 9.0 2.4 7.9 2.2 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Integrin_beta PF00362.18 KFP15851.1 - 2.3e-97 325.5 0.0 3.3e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain EGF_2 PF07974.13 KFP15851.1 - 2.4e-07 31.0 35.8 4.8e-05 23.6 13.9 5.4 6 0 0 6 6 6 3 EGF-like domain EGF_Tenascin PF18720.1 KFP15851.1 - 0.08 13.0 29.4 0.18 11.9 2.2 4.2 3 0 0 3 3 3 0 Tenascin EGF domain Sigma_reg_N PF13800.6 KFP15851.1 - 0.21 11.9 0.7 0.45 10.8 0.7 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal I-EGF_1 PF18372.1 KFP15851.1 - 0.6 10.3 45.7 0.031 14.4 7.5 4.6 4 0 0 4 4 4 0 Integrin beta epidermal growth factor like domain 1 ZU5 PF00791.20 KFP15854.1 - 1.9e-05 24.9 0.1 5.3e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 ZU5 domain Death PF00531.22 KFP15854.1 - 2.4e-05 24.4 0.9 0.25 11.5 0.0 3.1 2 1 0 2 2 2 2 Death domain SH3_2 PF07653.17 KFP15854.1 - 0.00056 19.5 0.2 0.0014 18.2 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain ABC_membrane_3 PF13748.6 KFP15855.1 - 0.066 12.4 0.5 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region RPA43_OB PF17875.1 KFP15856.1 - 1.1e-06 29.3 0.2 1.1e-06 29.3 0.2 3.4 1 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KFP15856.1 - 0.00034 20.9 0.1 0.00063 20.1 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_polI_A34 PF08208.11 KFP15856.1 - 0.22 11.6 21.3 0.35 10.9 21.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KFP15856.1 - 7.4 6.3 15.6 10 5.9 15.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GON PF08685.11 KFP15857.1 - 0.24 11.2 0.0 0.24 11.2 0.0 1.0 1 0 0 1 1 1 0 GON domain HLH PF00010.26 KFP15858.1 - 4.6e-17 61.7 0.6 4.6e-17 61.7 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Caskin-Pro-rich PF16907.5 KFP15858.1 - 0.098 13.2 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Hist_deacetyl PF00850.19 KFP15859.1 - 4.4e-77 259.6 0.0 4.4e-77 259.6 0.0 2.5 3 1 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.8 KFP15859.1 - 5.9e-35 119.3 47.7 5.9e-35 119.3 47.7 4.0 4 0 0 4 4 4 1 Glutamine rich N terminal domain of histone deacetylase 4 U-box PF04564.15 KFP15859.1 - 0.69 10.1 4.3 7.7 6.8 0.2 3.5 3 0 0 3 3 3 0 U-box domain Homeodomain PF00046.29 KFP15861.1 - 2.4e-19 68.9 7.6 2.8e-19 68.7 7.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15861.1 - 2e-05 24.4 2.1 3.8e-05 23.5 2.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP15861.1 - 0.027 14.6 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Homez PF11569.8 KFP15861.1 - 0.054 13.0 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 KFP15862.1 - 2.5e-19 68.9 7.6 3e-19 68.6 7.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15862.1 - 2.1e-05 24.3 2.1 3.9e-05 23.4 2.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP15862.1 - 0.028 14.6 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Homez PF11569.8 KFP15862.1 - 0.052 13.0 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeodomain PF00046.29 KFP15864.1 - 4.6e-20 71.2 7.0 5e-20 71.1 7.0 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP15864.1 - 0.00069 19.5 1.4 0.0011 18.8 1.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP15864.1 - 0.0056 16.1 0.2 0.0073 15.7 0.2 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF3528 PF12045.8 KFP15865.1 - 5.1e-60 202.2 1.8 8.3e-60 201.5 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFP15865.1 - 1.9e-19 69.2 8.3 3.2e-19 68.5 8.3 1.4 1 0 0 1 1 1 1 Homeodomain Baculo_p74_N PF08404.10 KFP15865.1 - 0.0033 16.6 0.1 0.0049 16.0 0.1 1.2 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal Homeobox_KN PF05920.11 KFP15865.1 - 0.033 14.1 0.7 0.072 13.0 0.7 1.6 1 0 0 1 1 1 0 Homeobox KN domain Auxin_canalis PF05703.11 KFP15865.1 - 5.1 6.9 6.8 2.1 8.2 4.1 1.5 1 1 1 2 2 2 0 Auxin canalisation Hox9_act PF04617.13 KFP15866.1 - 5.6e-43 147.8 13.7 2.5e-42 145.7 5.2 2.6 2 1 1 3 3 3 2 Hox9 activation region Homeodomain PF00046.29 KFP15866.1 - 6.3e-21 74.0 6.4 1.1e-20 73.3 6.4 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KFP15866.1 - 0.044 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain CI-B14_5a PF07347.12 KFP15866.1 - 0.052 13.4 0.2 0.15 12.0 0.2 1.7 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) RVT_1 PF00078.27 KFP15871.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) V-set PF07686.17 KFP15874.1 - 2e-09 37.6 0.4 1.3e-07 31.7 0.5 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP15874.1 - 7.3e-09 35.6 0.3 0.0001 22.3 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP15874.1 - 1.2e-08 35.4 0.1 4.3e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP15874.1 - 3.7e-08 33.4 0.1 1.4e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP15874.1 - 0.0023 18.2 0.1 2.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain RVT_1 PF00078.27 KFP15875.1 - 1.2e-33 116.5 0.0 1.8e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KFP15875.1 - 3.5e-17 62.0 2.1 6.4e-17 61.2 2.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Cobl PF09469.10 KFP15882.1 - 3.4e-43 145.8 4.0 4.8e-43 145.3 0.4 2.7 3 0 0 3 3 3 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFP15882.1 - 7.7e-07 29.1 0.5 0.00027 20.9 0.1 2.6 2 0 0 2 2 2 2 Raf-like Ras-binding domain Rad60-SLD PF11976.8 KFP15882.1 - 0.0018 18.0 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 KFP15882.1 - 0.0065 16.7 0.1 0.22 11.7 0.0 2.3 2 0 0 2 2 2 1 TUG ubiquitin-like domain Ubiquitin_5 PF18037.1 KFP15882.1 - 0.066 13.6 0.2 0.38 11.1 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain Pyridoxal_deC PF00282.19 KFP15884.1 - 3.6e-167 555.8 0.0 4.4e-167 555.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFP15884.1 - 0.0012 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFP15884.1 - 0.02 14.1 0.0 0.049 12.8 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II AAA PF00004.29 KFP15886.1 - 1.3e-37 129.2 0.0 2.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP15886.1 - 3.2e-09 36.4 0.0 2e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 KFP15886.1 - 1.9e-08 34.2 0.0 8.2e-08 32.1 0.0 2.2 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KFP15886.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFP15886.1 - 0.00082 19.8 0.8 0.34 11.3 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KFP15886.1 - 0.0017 18.4 0.1 0.0079 16.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFP15886.1 - 0.0027 17.9 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP15886.1 - 0.015 15.5 1.6 0.54 10.5 0.3 2.7 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 KFP15886.1 - 0.033 13.4 0.1 0.081 12.1 0.1 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KFP15886.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFP15886.1 - 0.14 11.5 0.1 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-H2C2_2 PF13465.6 KFP15887.1 - 4.5e-19 67.9 33.7 1.5e-06 28.3 0.2 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP15887.1 - 5.8e-16 58.0 44.9 1e-05 25.7 0.4 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP15887.1 - 3.5e-10 39.8 41.8 0.0002 21.9 0.4 6.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP15887.1 - 0.0057 16.4 0.2 0.0057 16.4 0.2 4.4 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFP15887.1 - 0.0061 16.3 0.1 0.0061 16.3 0.1 5.2 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP15887.1 - 0.012 15.9 25.4 0.44 10.9 0.0 5.7 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KFP15887.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.6 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.7 KFP15887.1 - 0.25 11.8 0.1 0.25 11.8 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type RNA_POL_M_15KD PF02150.16 KFP15887.1 - 0.49 10.3 11.4 6.4 6.7 0.0 5.2 6 0 0 6 6 6 0 RNA polymerases M/15 Kd subunit zf-RRPl_C4 PF17026.5 KFP15887.1 - 2.6 8.2 10.4 0.27 11.3 1.4 3.1 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_5 PF13719.6 KFP15887.1 - 6.9 6.5 12.7 0.3 10.9 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2HE PF16278.5 KFP15887.1 - 9.8 6.7 22.1 0.85 10.1 0.7 4.9 4 1 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Sp38 PF07354.12 KFP15888.1 - 1.7e-69 232.8 6.3 2.2e-69 232.4 6.3 1.1 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) GDE_N PF12439.8 KFP15888.1 - 0.08 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal TMF_TATA_bd PF12325.8 KFP15888.1 - 0.26 11.5 1.0 0.41 10.9 1.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding VWC PF00093.18 KFP15889.1 - 1.7e-12 47.4 51.1 1.1e-09 38.5 16.4 3.1 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.13 KFP15889.1 - 4.2e-05 23.2 4.1 4.2e-05 23.2 4.1 4.4 4 1 0 4 4 4 2 Pacifastin inhibitor (LCMII) zf-CCCH_2 PF14608.6 KFP15889.1 - 0.0038 17.6 4.1 0.11 13.0 0.1 4.8 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger DUF104 PF01954.16 KFP15894.1 - 0.078 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF104 PNP_UDP_1 PF01048.20 KFP15897.1 - 4e-23 81.9 0.0 4.7e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF5524 PF17662.1 KFP15898.1 - 1.3e-84 284.1 8.6 1.5e-84 283.8 8.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5524) Med10 PF09748.9 KFP15899.1 - 2.3e-27 95.4 0.1 2.4e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex UQ_con PF00179.26 KFP15900.1 - 2.8e-06 27.0 0.0 6.3e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme YndJ PF14158.6 KFP15900.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 YndJ-like protein Prok-E2_B PF14461.6 KFP15900.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B WGR PF05406.15 KFP15900.1 - 0.15 12.2 0.0 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 WGR domain Methyltr_RsmB-F PF01189.17 KFP15901.1 - 7.2e-40 136.8 0.0 7.4e-36 123.7 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFP15901.1 - 0.0033 17.5 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Steroid_dh PF02544.16 KFP15902.1 - 1.1e-43 148.8 0.4 1.2e-43 148.6 0.4 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFP15902.1 - 1.5e-05 24.6 0.1 1.6e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Guanylate_cyc PF00211.20 KFP15904.1 - 5.7e-122 404.1 1.3 1.3e-64 217.2 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.14 KFP15904.1 - 1.4e-36 125.2 0.6 2.5e-36 124.3 0.6 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) AC_N PF16214.5 KFP15904.1 - 2.2e-26 92.9 10.7 2.2e-26 92.9 10.7 2.1 3 0 0 3 3 3 1 Adenylyl cyclase N-terminal extracellular and transmembrane region HNOBA PF07701.14 KFP15904.1 - 0.021 14.2 1.4 0.079 12.4 0.4 2.1 2 0 0 2 2 2 0 Heme NO binding associated DUF349 PF03993.12 KFP15904.1 - 0.98 9.8 5.8 2.1 8.7 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF4462 PF14692.6 KFP15906.1 - 0.14 11.6 0.1 0.49 9.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) FAST_2 PF08368.12 KFP15907.1 - 5e-23 81.7 0.1 1.6e-22 80.1 0.1 1.9 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFP15907.1 - 4.1e-19 68.3 1.7 4.1e-19 68.3 1.7 4.0 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFP15907.1 - 1.8e-13 50.4 0.0 4.7e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 RAP domain RNA_pol_N PF01194.17 KFP15907.1 - 0.12 12.7 0.2 0.57 10.5 0.1 2.2 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit FAD_binding_1 PF00667.20 KFP15908.1 - 6e-45 153.5 0.0 1e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP15908.1 - 3.8e-28 98.5 0.0 7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFP15908.1 - 5e-14 52.9 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KFP15908.1 - 6.9e-06 26.4 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Sema PF01403.19 KFP15909.1 - 2.7e-114 382.3 0.0 3.7e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 KFP15909.1 - 7.1e-47 157.4 93.6 8.2e-12 45.2 5.2 7.5 7 0 0 7 7 7 6 Thrombospondin type 1 domain Methyltransf_23 PF13489.6 KFP15914.1 - 3.8e-05 23.6 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP15914.1 - 0.0011 19.7 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP15914.1 - 0.0093 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KFP15914.1 - 0.019 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 KFP15914.1 - 0.021 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFP15914.1 - 0.064 12.8 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.18 KFP15914.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Methyltransf_11 PF08241.12 KFP15914.1 - 0.13 13.0 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KFP15914.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KFP15914.1 - 0.19 11.5 0.0 0.49 10.1 0.0 1.6 1 1 1 2 2 2 0 Met-10+ like-protein Cpn60_TCP1 PF00118.24 KFP15915.1 - 8.5e-160 532.6 4.7 1e-159 532.3 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KFP15916.1 - 1.1e-43 149.5 0.0 1.4e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15916.1 - 5.7e-21 75.0 0.0 6.5e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP15916.1 - 7.2e-05 22.2 0.0 0.00021 20.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFP15916.1 - 0.01 15.5 0.0 0.98 9.0 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DLH PF01738.18 KFP15917.1 - 1.3e-41 142.6 0.0 1.5e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFP15917.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFP15917.1 - 0.00013 21.6 0.1 0.0023 17.4 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFP15917.1 - 0.00033 20.4 0.0 0.034 13.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP15917.1 - 0.00091 18.6 0.0 0.051 12.8 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP15917.1 - 0.0098 16.5 0.0 0.09 13.4 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFP15917.1 - 0.029 14.2 0.1 0.17 11.7 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KFP15918.1 - 1.2e-42 145.9 0.0 1.4e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFP15918.1 - 2.7e-06 27.3 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFP15918.1 - 3.4e-06 26.7 0.1 0.00023 20.7 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFP15918.1 - 1.2e-05 25.1 0.1 0.0013 18.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 KFP15918.1 - 2.2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KFP15918.1 - 0.00011 21.5 0.1 0.2 10.9 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KFP15918.1 - 0.003 17.4 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KFP15918.1 - 0.027 15.1 0.0 0.092 13.3 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFP15918.1 - 0.031 14.2 0.0 0.087 12.7 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KFP15919.1 - 1.7e-35 122.5 0.0 2e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFP15919.1 - 3.8e-08 33.4 0.0 5.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFP15919.1 - 3.2e-07 30.3 0.1 0.00038 20.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP15919.1 - 9e-06 25.3 0.1 0.036 13.6 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFP15919.1 - 0.00011 22.1 0.0 0.086 12.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP15919.1 - 0.00041 19.7 0.1 0.12 11.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFP15919.1 - 0.00048 19.1 0.0 0.00072 18.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFP15919.1 - 0.0014 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase FSH1 PF03959.13 KFP15919.1 - 0.0023 17.6 0.1 0.019 14.6 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF915 PF06028.11 KFP15919.1 - 0.0024 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KFP15919.1 - 0.0042 17.7 0.0 0.0052 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KFP15919.1 - 0.11 12.4 0.2 0.75 9.7 0.1 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.22 KFP15919.1 - 0.21 11.5 0.0 0.45 10.4 0.0 1.5 1 1 0 1 1 1 0 Cutinase RINGv PF12906.7 KFP15920.1 - 8.6e-15 54.6 8.6 2e-14 53.5 8.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFP15920.1 - 1.7 9.0 15.7 0.058 13.7 9.3 2.0 2 0 0 2 2 2 0 Ring finger domain DUF2373 PF10180.9 KFP15921.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Nucleo_P87 PF07267.11 KFP15922.1 - 9.3 5.0 11.0 11 4.7 11.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ank_5 PF13857.6 KFP15923.1 - 1.3e-15 57.2 1.0 8.4e-07 29.2 0.3 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP15923.1 - 5.4e-15 55.7 0.3 1.1e-14 54.7 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP15923.1 - 9.9e-15 54.7 0.8 4.7e-07 30.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP15923.1 - 2.6e-07 30.4 0.3 0.12 13.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFP15923.1 - 7.2e-07 29.4 0.5 0.00043 20.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat CUB PF00431.20 KFP15925.1 - 3.8e-15 56.2 0.0 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.20 KFP15925.1 - 2.4e-08 34.5 0.1 3.9e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) PTCB-BRCT PF12738.7 KFP15931.1 - 3.6e-20 71.7 3.5 5.5e-18 64.7 0.6 3.4 3 0 0 3 3 3 1 twin BRCT domain BRCT_2 PF16589.5 KFP15931.1 - 2.3e-17 63.2 0.4 2.3e-08 34.3 0.0 3.5 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFP15931.1 - 4.8e-16 58.9 2.8 3.6e-05 24.1 0.1 3.8 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 KFP15931.1 - 0.013 15.6 9.3 0.99 9.5 0.2 4.4 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFP15931.1 - 0.041 14.2 1.9 0.22 11.9 0.2 2.8 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFP15931.1 - 0.061 13.2 0.1 2.8 7.9 0.0 3.1 3 1 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF1351 PF07083.11 KFP15931.1 - 0.12 12.1 1.5 0.27 11.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) PRKG1_interact PF15898.5 KFP15931.1 - 0.18 12.7 6.1 0.47 11.4 0.7 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Fibrinogen_C PF00147.18 KFP15933.1 - 2.1e-69 233.7 7.7 3.1e-69 233.2 7.7 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Spc29 PF17082.5 KFP15933.1 - 0.0055 16.6 13.9 0.082 12.7 2.9 2.3 1 1 1 2 2 2 2 Spindle Pole Component 29 DUF3601 PF12208.8 KFP15933.1 - 0.014 15.5 0.3 0.071 13.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) DivIC PF04977.15 KFP15933.1 - 1.3 8.8 19.7 0.042 13.6 2.9 3.6 1 1 3 4 4 4 0 Septum formation initiator DUF724 PF05266.14 KFP15933.1 - 2.5 7.9 14.3 1.1 9.1 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_lysis PF03245.13 KFP15933.1 - 4 7.6 11.6 0.089 12.9 4.2 2.0 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein TMPIT PF07851.13 KFP15933.1 - 4.7 6.4 18.4 0.15 11.3 10.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein Acyltransferase PF01553.21 KFP15936.1 - 1.4e-18 66.8 0.1 3e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 KFP15936.1 - 2.6e-18 65.9 0.8 5.9e-18 64.7 0.8 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus zf-DNL PF05180.12 KFP15936.1 - 0.09 12.7 0.7 15 5.6 0.1 2.6 2 0 0 2 2 2 0 DNL zinc finger Tmemb_14 PF03647.13 KFP15937.1 - 2.8e-28 98.5 8.2 3.1e-28 98.3 8.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C FTR1 PF03239.14 KFP15937.1 - 0.021 14.0 2.7 0.024 13.8 2.7 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family GST_N PF02798.20 KFP15938.1 - 1e-17 64.2 0.0 2.2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP15938.1 - 1.6e-16 60.3 0.2 3.1e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP15938.1 - 1.5e-14 54.0 0.1 2.5e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP15938.1 - 0.076 13.4 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP15939.1 - 6.9e-20 71.1 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP15939.1 - 3.2e-18 65.7 0.0 5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP15939.1 - 1.2e-17 64.0 0.0 2.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP15939.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP15939.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sa_NUDIX PF18167.1 KFP15939.1 - 0.074 12.8 0.0 0.35 10.6 0.0 1.9 1 1 1 2 2 2 0 SMODS-associated NUDIX domain GST_C_3 PF14497.6 KFP15940.1 - 1.1e-11 44.8 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP15940.1 - 1.3e-11 44.6 0.0 2.6e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 KFP15941.1 - 9.7e-79 264.4 0.0 1.3e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15941.1 - 4.5e-37 127.7 0.1 2.1e-36 125.6 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP15941.1 - 0.00072 18.6 0.1 0.0015 17.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Anoct_dimer PF16178.5 KFP15941.1 - 0.005 16.6 0.6 0.01 15.5 0.6 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin F-box-like PF12937.7 KFP15942.1 - 9.7e-12 44.6 1.4 1.8e-11 43.7 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP15942.1 - 2.2e-08 33.8 1.6 4.1e-08 32.9 1.6 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KFP15942.1 - 0.00044 20.3 0.8 0.00083 19.4 0.8 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Xol-1_N PF09108.10 KFP15942.1 - 0.034 14.0 0.2 0.058 13.3 0.2 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal GCM PF03615.15 KFP15943.1 - 3.2e-70 234.5 4.9 5.3e-70 233.8 4.9 1.3 1 0 0 1 1 1 1 GCM motif protein ELO PF01151.18 KFP15944.1 - 2.5e-67 227.0 25.4 3.1e-67 226.7 25.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GCS PF03074.16 KFP15945.1 - 3.2e-181 602.6 0.0 3.9e-181 602.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KFP15945.1 - 0.032 13.6 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) SANT_DAMP1_like PF16282.5 KFP15945.1 - 0.066 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Kelch_1 PF01344.25 KFP15947.1 - 9.2e-47 156.4 10.9 1.8e-11 43.4 0.0 6.6 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP15947.1 - 4.9e-33 112.3 3.2 5.9e-08 32.7 0.2 6.1 3 1 3 6 6 6 5 Kelch motif BACK PF07707.15 KFP15947.1 - 2e-25 88.9 0.1 4.6e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFP15947.1 - 3.4e-23 81.4 0.9 4.4e-06 26.8 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KFP15947.1 - 1.8e-21 76.5 0.6 4.4e-21 75.2 0.4 1.8 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP15947.1 - 5.9e-19 67.2 6.0 2.1e-07 30.6 0.2 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFP15947.1 - 6.1e-18 64.6 0.7 0.00013 21.9 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP15947.1 - 1.1e-10 41.2 5.4 0.0034 17.3 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.11 KFP15947.1 - 0.00035 19.9 1.4 0.065 12.4 0.3 2.6 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 KFP15947.1 - 0.026 15.0 0.3 11 6.7 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain DUF1668 PF07893.13 KFP15947.1 - 0.058 12.7 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) DnaJ PF00226.31 KFP15947.1 - 0.12 12.5 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain ThiG PF05690.14 KFP15947.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG LRR_8 PF13855.6 KFP15948.1 - 1e-32 111.6 38.2 1.8e-08 34.0 3.2 6.1 3 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP15948.1 - 3.2e-29 100.5 47.1 3e-05 24.3 0.0 8.4 6 1 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP15948.1 - 4.5e-10 39.3 17.9 0.00022 20.8 2.1 4.8 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KFP15948.1 - 0.0049 17.2 39.0 10 7.1 0.1 12.4 9 3 2 11 11 11 2 Leucine Rich Repeat Tropomyosin_1 PF12718.7 KFP15948.1 - 0.055 13.6 3.1 0.14 12.3 3.1 1.6 1 0 0 1 1 1 0 Tropomyosin like HMw1_D2 PF18254.1 KFP15948.1 - 0.13 12.6 1.2 3.7 8.0 0.0 3.8 4 1 0 4 4 4 0 HMW1 domain 2 DUF2322 PF10084.9 KFP15948.1 - 0.2 11.7 0.3 3.5 7.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) H-kinase_dim PF02895.14 KFP15948.1 - 0.7 10.3 5.1 0.3 11.5 0.3 2.9 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain MLIP PF15274.6 KFP15949.1 - 4e-121 403.6 1.7 7.2e-121 402.8 1.7 1.4 1 1 0 1 1 1 1 Muscular LMNA-interacting protein Peptidase_C1 PF00112.23 KFP15951.1 - 5.5e-54 183.5 6.6 5.5e-54 183.5 6.6 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Pacifastin_I PF05375.13 KFP15951.1 - 0.00033 20.3 2.9 0.0014 18.3 2.9 2.2 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Propeptide_C1 PF08127.13 KFP15951.1 - 0.0012 18.6 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Somatomedin_B PF01033.17 KFP15951.1 - 0.013 15.9 16.3 0.013 15.9 16.3 2.6 2 0 0 2 2 2 0 Somatomedin B domain Peptidase_C1_2 PF03051.15 KFP15951.1 - 0.066 12.0 2.8 0.081 11.7 0.9 1.9 3 0 0 3 3 3 0 Peptidase C1-like family FAM83 PF07894.12 KFP15956.1 - 9.7e-107 356.6 0.1 2.1e-106 355.5 0.1 1.6 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFP15956.1 - 1.2e-09 38.2 0.2 2.2e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 PLD-like domain Regulator_TrmB PF11495.8 KFP15956.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB 7tm_1 PF00001.21 KFP15958.1 - 5.6e-58 196.3 22.1 6.9e-58 196.0 22.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orexin_rec2 PF03827.13 KFP15958.1 - 8.9e-30 102.5 1.2 8.9e-30 102.5 1.2 2.5 3 0 0 3 3 3 1 Orexin receptor type 2 7TM_GPCR_Srsx PF10320.9 KFP15958.1 - 0.00014 21.3 21.1 0.00051 19.5 21.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP15958.1 - 0.00061 19.6 10.5 0.00061 19.6 10.5 1.8 2 0 0 2 2 2 1 Olfactory receptor DUF5453 PF17534.2 KFP15958.1 - 0.52 10.3 4.5 0.16 11.9 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5453) GDNF PF02351.16 KFP15959.1 - 1.5e-21 77.1 50.3 1.5e-10 41.9 16.9 3.6 3 1 1 4 4 4 3 GDNF/GAS1 domain DUF1874 PF08960.10 KFP15959.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) HMGL-like PF00682.19 KFP15961.1 - 1.4e-66 224.8 0.0 1.6e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 HMGL-like TGFb_propeptide PF00688.18 KFP15962.1 - 7.1e-93 310.9 0.0 1.1e-92 310.2 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP15962.1 - 2e-37 128.3 0.6 5.6e-37 126.9 0.5 1.8 2 0 0 2 2 2 1 Transforming growth factor beta like domain YkuD_2 PF13645.6 KFP15962.1 - 0.073 12.5 1.1 0.14 11.6 0.2 1.8 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain MAP17 PF15807.5 KFP15963.1 - 4.8e-36 123.8 0.3 5.2e-36 123.6 0.3 1.0 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SurA_N_2 PF13623.6 KFP15963.1 - 0.0085 16.0 0.1 0.0094 15.8 0.1 1.1 1 0 0 1 1 1 1 SurA N-terminal domain EI24 PF07264.11 KFP15963.1 - 0.026 14.8 0.0 0.029 14.6 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF371 PF04027.13 KFP15963.1 - 0.055 13.4 0.2 0.07 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF371) ETRAMP PF09716.10 KFP15963.1 - 0.073 13.1 0.8 0.89 9.7 0.1 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TPR_21 PF09976.9 KFP15963.1 - 0.076 12.7 0.1 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Epiglycanin_C PF14654.6 KFP15963.1 - 0.091 12.8 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Fer4_5 PF12801.7 KFP15963.1 - 0.11 12.5 1.9 0.11 12.5 1.9 1.6 2 0 0 2 2 2 0 4Fe-4S binding domain p450 PF00067.22 KFP15964.1 - 3e-119 398.8 0.0 3.6e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPO_TPO PF00758.18 KFP15964.1 - 0.0043 17.1 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin p450 PF00067.22 KFP15965.1 - 3.8e-123 411.7 0.0 4.5e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_6 PF13405.6 KFP15966.1 - 0.0017 18.2 0.4 2.1 8.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP15966.1 - 0.0017 17.7 0.1 0.77 9.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP15966.1 - 0.0027 18.1 1.4 0.17 12.3 0.9 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP15966.1 - 0.005 16.3 0.3 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 EF hand BLOC1_2 PF10046.9 KFP15966.1 - 0.0086 16.4 4.3 0.0086 16.4 4.3 3.5 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF730 PF05325.11 KFP15966.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Atg14 PF10186.9 KFP15966.1 - 0.19 10.8 10.2 0.059 12.4 1.4 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 KFP15966.1 - 0.39 10.7 15.2 0.1 12.5 1.6 3.6 3 0 0 3 3 3 0 Prefoldin subunit CC2-LZ PF16516.5 KFP15966.1 - 0.56 10.6 9.1 0.34 11.3 1.4 3.4 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4570 PF15134.6 KFP15966.1 - 2.1 8.4 6.0 0.74 9.9 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Fib_alpha PF08702.10 KFP15966.1 - 9.3 6.4 17.1 0.31 11.2 2.4 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ATP11 PF06644.11 KFP15967.1 - 9.8e-50 169.8 0.9 1.1e-49 169.7 0.9 1.0 1 0 0 1 1 1 1 ATP11 protein Pkinase PF00069.25 KFP15968.1 - 5.8e-68 229.1 0.0 8.8e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15968.1 - 9.8e-30 103.7 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP15968.1 - 1.3e-06 27.9 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RRN7 PF11781.8 KFP15968.1 - 0.00052 19.6 0.2 0.0016 18.1 0.2 1.9 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkinase_fungal PF17667.1 KFP15968.1 - 0.00062 18.6 0.0 0.001 17.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP15968.1 - 0.0041 17.1 0.1 1.7 8.5 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP15968.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Homeodomain PF00046.29 KFP15969.1 - 5.2e-22 77.4 3.9 5.2e-22 77.4 3.9 2.2 2 0 0 2 2 2 1 Homeodomain OAR PF03826.17 KFP15969.1 - 8.1e-06 25.5 1.2 2.1e-05 24.2 1.2 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP15969.1 - 0.0091 15.9 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF778 PF05608.12 KFP15969.1 - 0.76 10.1 6.7 2.1 8.7 5.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Amidase PF01425.21 KFP15971.1 - 1.6e-110 370.2 0.0 1.8e-110 370.0 0.0 1.0 1 0 0 1 1 1 1 Amidase LRR_6 PF13516.6 KFP15972.1 - 0.0052 16.7 5.9 0.58 10.4 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat SNF2_N PF00176.23 KFP15974.1 - 1e-58 198.7 0.0 1.7e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP15974.1 - 2.4e-16 60.1 0.0 5.2e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP15974.1 - 1.4e-08 35.0 0.0 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP15974.1 - 2.8e-07 30.5 0.0 8.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFP15974.1 - 7.4e-07 28.6 0.1 4.2e-06 26.1 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.10 KFP15974.1 - 5.1e-06 26.8 0.1 0.00017 21.8 0.1 2.5 2 0 0 2 2 2 1 Rad54 N terminal DUF2075 PF09848.9 KFP15974.1 - 0.16 11.2 0.0 0.5 9.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GNT-I PF03071.15 KFP15977.1 - 1.7e-49 168.8 0.1 4e-49 167.5 0.1 1.5 1 1 0 1 1 1 1 GNT-I family ILEI PF15711.5 KFP15977.1 - 1.2e-24 86.5 0.0 2.8e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer MGAT2 PF05060.14 KFP15977.1 - 0.043 12.9 0.0 1 8.3 0.0 2.3 2 0 0 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) Tetraspanin PF00335.20 KFP15978.1 - 5.5e-41 140.8 13.0 6.3e-41 140.6 13.0 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFP15978.1 - 0.51 10.0 5.5 0.73 9.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2160 PF09928.9 KFP15978.1 - 0.91 9.9 6.9 0.12 12.8 2.2 2.0 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) Kinocilin PF15033.6 KFP15978.1 - 1.7 8.3 9.8 0.28 10.8 0.5 2.9 2 1 1 3 3 3 0 Kinocilin protein SUR7 PF06687.12 KFP15978.1 - 9.3 5.8 14.8 19 4.8 14.9 1.6 1 1 0 1 1 1 0 SUR7/PalI family PI3K_P85_iSH2 PF16454.5 KFP15979.1 - 8.6e-64 214.0 20.7 1.3e-63 213.4 20.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SH2 PF00017.24 KFP15979.1 - 2.2e-41 139.8 0.0 1.3e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 KFP15979.1 - 1.7e-12 47.4 0.1 1.8e-11 44.1 0.0 2.5 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 KFP15979.1 - 4.7e-06 26.1 0.2 0.00065 19.3 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP15979.1 - 6.2e-06 26.0 0.1 1.9e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP15979.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Mod_r PF07200.13 KFP15979.1 - 0.15 12.2 14.3 0.15 12.1 5.6 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5638 PF18688.1 KFP15979.1 - 0.44 10.9 7.5 0.055 13.8 1.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5638) Transcrip_act PF04949.13 KFP15979.1 - 1.3 8.9 13.0 4.2 7.2 4.6 2.9 1 1 2 3 3 3 0 Transcriptional activator Laminin_II PF06009.12 KFP15979.1 - 1.3 9.0 5.4 12 6.0 0.8 2.6 3 0 0 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 KFP15979.1 - 2.3 7.7 7.2 3.7 7.0 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFP15979.1 - 3.9 7.5 5.3 1.9 8.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KFP15979.1 - 4 6.7 6.1 5.9 6.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1908 PF08926.11 KFP15980.1 - 5.2e-141 468.7 0.7 5.2e-141 468.7 0.7 3.1 3 1 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFP15980.1 - 9.4e-63 212.0 0.0 1.7e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP15980.1 - 2.8e-26 92.3 0.0 6.3e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFP15980.1 - 1.1e-11 44.4 0.1 6.3e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFP15980.1 - 6.9e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP15980.1 - 3.7e-07 30.4 0.0 9.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFP15980.1 - 4.6e-05 23.4 0.0 0.05 13.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP15980.1 - 0.00056 19.3 0.0 0.0031 16.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Tricorn_PDZ PF14685.6 KFP15980.1 - 0.0084 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Pkinase_fungal PF17667.1 KFP15980.1 - 0.0093 14.8 0.6 0.03 13.1 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP15980.1 - 0.033 13.1 0.1 0.033 13.1 0.1 2.2 3 0 0 3 3 1 0 Haspin like kinase domain RIO1 PF01163.22 KFP15980.1 - 0.038 13.6 0.0 0.038 13.6 0.0 2.0 3 0 0 3 3 3 0 RIO1 family ACTL7A_N PF16840.5 KFP15980.1 - 0.1 12.7 0.2 0.26 11.4 0.2 1.7 1 0 0 1 1 1 0 Actin-like protein 7A N-terminus Folate_rec PF03024.14 KFP15983.1 - 2.2e-55 187.2 26.1 3.6e-55 186.5 26.1 1.3 1 0 0 1 1 1 1 Folate receptor family TMEM206 PF15122.6 KFP15983.1 - 0.033 13.4 0.1 0.049 12.8 0.1 1.2 1 0 0 1 1 1 0 TMEM206 protein family Kelch_1 PF01344.25 KFP15984.1 - 7.8e-74 243.1 21.8 8.4e-15 54.1 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP15984.1 - 5.6e-51 169.3 3.8 5.1e-10 39.3 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFP15984.1 - 2.3e-31 107.9 0.8 6.8e-31 106.4 0.6 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFP15984.1 - 8.4e-27 92.9 3.5 5.7e-05 23.3 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP15984.1 - 3.1e-23 81.5 1.7 0.00013 21.9 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP15984.1 - 3e-22 77.7 13.6 7.7e-07 28.9 0.1 6.7 6 2 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFP15984.1 - 2.2e-09 37.1 8.4 0.042 13.8 0.0 6.0 6 0 0 6 6 6 3 Kelch motif BTB PF00651.31 KFP15984.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SAM_3 PF18016.1 KFP15984.1 - 0.15 11.9 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) She2p PF11435.8 KFP15984.1 - 0.16 11.6 0.4 0.96 9.1 0.2 2.1 1 1 1 2 2 2 0 RNA binding protein She2p DUF3429 PF11911.8 KFP15985.1 - 1e-36 126.4 9.9 1.3e-36 126.0 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Vasculin PF15337.6 KFP15986.1 - 7.1e-43 145.4 3.5 2.3e-42 143.8 3.5 1.9 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 SHNi-TPR PF10516.9 KFP15988.1 - 5.1e-15 54.6 6.4 7.8e-15 54.1 1.5 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 KFP15988.1 - 9.5e-10 38.6 11.7 2.6e-08 34.0 5.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP15988.1 - 2e-08 33.7 5.3 0.016 15.0 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP15988.1 - 4.4e-07 29.5 16.2 0.019 15.1 0.3 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP15988.1 - 1.2e-05 25.1 7.2 0.11 12.8 0.3 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP15988.1 - 0.013 16.3 6.7 0.076 13.9 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP15988.1 - 0.039 13.6 6.8 21 4.9 5.1 4.3 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 KFP15988.1 - 0.078 13.6 5.4 7 7.5 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP15988.1 - 0.19 12.4 13.4 0.96 10.1 1.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP15988.1 - 0.49 10.6 2.3 30 5.0 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KFP15989.1 - 5.9e-53 180.0 0.1 1.1e-52 179.1 0.1 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.20 KFP15989.1 - 0.039 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 S-layer homology domain AhpC-TSA PF00578.21 KFP15990.1 - 8.1e-42 142.1 0.0 1.3e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP15990.1 - 2.2e-16 59.9 0.0 3.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFP15990.1 - 5.5e-15 54.9 0.1 9.9e-15 54.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Endothelin PF00322.17 KFP15990.1 - 0.19 11.3 0.7 0.4 10.3 0.7 1.5 1 0 0 1 1 1 0 Endothelin family MMACHC PF16690.5 KFP15992.1 - 1.1e-101 339.0 0.2 1.2e-101 338.9 0.2 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Dicty_REP PF05086.12 KFP15993.1 - 8.4 4.2 7.6 9.7 4.0 7.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase_Tyr PF07714.17 KFP15995.1 - 9.2e-43 146.4 0.0 9.8e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP15995.1 - 9.3e-41 139.9 0.0 1.1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFP15995.1 - 0.00016 20.6 0.0 0.0002 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP15995.1 - 0.00022 20.6 0.1 0.00037 19.9 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CAF1 PF04857.20 KFP15996.1 - 1.5e-60 205.0 0.1 1.3e-42 146.2 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease zf-CCCH PF00642.24 KFP15996.1 - 3.3e-05 23.7 0.1 9.8e-05 22.2 0.1 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HhH-GPD PF00730.25 KFP15997.1 - 4.3e-22 78.6 0.0 8.4e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KFP15997.1 - 1e-19 70.5 0.1 2.6e-19 69.3 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KFP15997.1 - 3.6e-09 36.0 0.3 1.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KFP15997.1 - 0.039 14.3 4.8 0.039 14.3 4.8 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III SelP_N PF04592.14 KFP15998.1 - 6e-27 94.6 1.1 6.4e-27 94.5 1.1 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SWIM PF04434.17 KFP15999.1 - 0.063 13.0 2.0 0.15 11.7 2.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger URO-D PF01208.17 KFP16000.1 - 1.5e-134 448.6 0.0 1.6e-134 448.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HECT PF00632.25 KFP16001.1 - 4e-53 180.9 0.0 6.1e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 KFP16001.1 - 1e-13 51.3 0.1 1.7e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFP16001.1 - 0.011 15.8 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 F5/8 type C domain HECT PF00632.25 KFP16003.1 - 4.7e-54 183.9 0.1 6.4e-54 183.5 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4954 PF16314.5 KFP16004.1 - 7.4e-06 24.4 2.6 1.3e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep PF00132.24 KFP16004.1 - 0.00017 21.2 9.6 0.046 13.5 3.3 3.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KFP16004.1 - 0.00041 20.0 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KFP16004.1 - 0.00081 18.4 1.0 0.00081 18.4 1.0 1.8 2 0 0 2 2 2 1 L-fucokinase DFF-C PF09033.10 KFP16004.1 - 0.11 12.4 0.4 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Pkinase PF00069.25 KFP16005.1 - 5.5e-67 225.9 0.0 8.5e-67 225.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16005.1 - 8.4e-33 113.7 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KFP16005.1 - 1.5e-31 108.4 2.6 6.8e-18 64.6 0.3 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KFP16005.1 - 8.8e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP16005.1 - 4.7e-05 22.3 0.0 9.7e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF5105 PF17118.5 KFP16005.1 - 0.033 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) Kdo PF06293.14 KFP16005.1 - 1.6 8.0 4.0 1.1 8.6 0.2 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bestrophin PF01062.21 KFP16006.1 - 1.3e-111 372.7 4.0 1.5e-111 372.5 4.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribosomal_S8e PF01201.22 KFP16007.1 - 3.8e-53 179.3 0.9 4.4e-53 179.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e ICAT PF06384.11 KFP16007.1 - 0.06 13.6 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Kinesin PF00225.23 KFP16008.1 - 3.6e-94 315.4 0.1 3.6e-94 315.4 0.1 2.1 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP16008.1 - 2.6e-16 59.9 1.6 3e-15 56.5 0.0 2.7 2 1 0 2 2 2 1 Microtubule binding DUF4685 PF15737.5 KFP16008.1 - 0.76 10.2 8.8 0.55 10.7 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4685) DUF5578 PF17741.1 KFP16009.1 - 1.5e-131 437.7 0.8 1.8e-131 437.5 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Drf_GBD PF06371.13 KFP16009.1 - 0.012 15.2 0.2 0.13 11.8 0.1 2.2 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain HEAT_2 PF13646.6 KFP16009.1 - 0.02 15.3 0.8 0.064 13.7 0.5 2.0 2 0 0 2 2 2 0 HEAT repeats E3_UbLigase_R4 PF13764.6 KFP16009.1 - 0.19 9.9 0.0 0.26 9.4 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF829 PF05705.14 KFP16010.1 - 5.5e-62 209.8 0.1 6.2e-62 209.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RNF220 PF15926.5 KFP16011.1 - 7.5e-77 258.3 13.7 2.3e-49 168.3 2.5 2.9 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KFP16011.1 - 1.8e-09 37.2 6.7 1.8e-09 37.2 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP16011.1 - 0.012 15.7 4.6 0.012 15.7 4.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP16011.1 - 0.021 14.7 5.3 0.021 14.7 5.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pox_A_type_inc PF04508.12 KFP16011.1 - 0.027 14.3 0.4 0.093 12.6 0.4 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat zf-C3HC4_3 PF13920.6 KFP16011.1 - 0.24 11.3 10.4 0.099 12.5 4.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP16011.1 - 1 9.4 11.6 0.3 11.1 4.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KFP16011.1 - 1.2 9.5 12.6 0.79 10.1 6.6 2.6 2 0 0 2 2 2 0 Ring finger domain RNase_T PF00929.24 KFP16012.1 - 2.7e-37 128.9 0.0 3.3e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease 7tm_4 PF13853.6 KFP16013.1 - 5.5e-43 147.7 16.2 6.6e-43 147.4 16.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16013.1 - 2.4e-30 105.8 14.1 3.8e-30 105.1 14.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP16014.1 - 5.2e-36 124.8 10.3 6.1e-36 124.6 10.3 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16014.1 - 1.2e-23 83.8 18.1 1.8e-23 83.2 18.1 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1700 PF08006.11 KFP16014.1 - 0.31 10.5 3.9 0.67 9.5 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) TPR_2 PF07719.17 KFP16019.1 - 1.1e-24 84.4 12.2 0.0012 18.8 0.1 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFP16019.1 - 9.8e-22 75.8 16.2 0.00089 19.0 0.3 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFP16019.1 - 1.2e-17 64.0 11.5 0.00035 20.8 0.2 6.1 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFP16019.1 - 2.2e-15 55.5 9.4 0.0059 16.7 0.0 6.5 8 0 0 8 8 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP16019.1 - 2.6e-15 55.8 2.8 0.007 17.1 0.0 7.3 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP16019.1 - 6e-11 42.7 10.2 0.0069 16.9 0.0 5.5 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFP16019.1 - 7.3e-10 38.2 11.7 0.14 12.3 0.0 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFP16019.1 - 2.9e-08 34.2 11.2 0.071 13.8 0.4 6.3 6 3 1 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP16019.1 - 2.2e-07 30.8 10.7 0.003 17.8 0.3 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP16019.1 - 1.4e-06 27.7 4.7 4e-06 26.3 1.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP16019.1 - 3.5e-06 27.3 16.4 2 9.2 0.4 7.0 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP16019.1 - 4.6e-06 26.7 1.0 0.19 11.9 0.1 4.6 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP16019.1 - 0.0016 18.2 6.4 0.17 11.8 1.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP16019.1 - 0.0052 16.4 12.0 2.4 7.9 0.9 5.5 3 1 2 5 5 5 1 TPR repeat ANAPC3 PF12895.7 KFP16019.1 - 0.022 15.0 1.3 0.022 15.0 1.3 4.4 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KFP16019.1 - 0.03 13.3 4.2 1.9 7.3 0.0 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 KFP16019.1 - 0.037 12.7 0.1 0.088 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 KFP16019.1 - 0.049 14.3 0.3 6.3 7.7 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat WD40 PF00400.32 KFP16020.1 - 1.2e-62 206.3 85.9 1.2e-05 25.9 0.1 27.2 30 0 0 30 30 30 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16020.1 - 1.4e-38 131.1 5.7 1.3e-07 31.8 0.0 12.9 8 3 5 14 14 14 8 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 KFP16020.1 - 1.5e-38 130.5 0.2 7.1e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 HELP motif Ge1_WD40 PF16529.5 KFP16020.1 - 6.1e-07 28.7 3.6 0.35 9.8 0.0 6.8 4 3 3 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFP16020.1 - 1.6e-05 23.9 0.0 0.11 11.2 0.0 4.0 4 0 0 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KFP16020.1 - 4.8e-05 22.1 10.6 0.16 10.5 0.0 6.7 7 1 1 8 8 8 2 Cytochrome D1 heme domain Frtz PF11768.8 KFP16020.1 - 0.00058 18.3 0.0 1.3 7.2 0.0 4.0 4 0 0 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KFP16020.1 - 0.032 12.9 0.0 6.8 5.2 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFP16020.1 - 0.12 12.3 1.3 2.1e+02 2.0 0.0 4.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat zf-CCCH_2 PF14608.6 KFP16021.1 - 9.2e-18 64.0 57.9 0.00013 22.3 7.4 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger PWI PF01480.17 KFP16021.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PWI domain DAHP_snth_FXD PF18152.1 KFP16021.1 - 0.14 12.1 2.2 0.34 10.8 0.2 2.4 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain HSD3 PF15244.6 KFP16022.1 - 6.9e-37 127.9 3.4 1e-36 127.4 3.4 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 7, or HSD3 CARD PF00619.21 KFP16022.1 - 0.015 15.3 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Caspase recruitment domain PUF PF00806.19 KFP16022.1 - 0.026 14.2 0.1 0.07 12.8 0.1 1.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat GCD14 PF08704.10 KFP16022.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ion_trans_2 PF07885.16 KFP16023.1 - 1.6e-37 127.3 21.8 5.2e-19 68.0 9.7 3.3 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFP16023.1 - 5.2e-07 29.2 11.3 1.1e-06 28.1 0.3 2.5 2 1 0 2 2 2 1 Ion transport protein DUF2390 PF09523.10 KFP16023.1 - 0.029 14.7 0.4 0.029 14.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) PLC-beta_C PF08703.10 KFP16023.1 - 0.03 14.3 0.2 0.058 13.4 0.2 1.4 1 0 0 1 1 1 0 PLC-beta C terminal TssN PF17555.2 KFP16023.1 - 0.074 12.4 4.1 0.37 10.1 2.4 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN PDZ_3 PF17815.1 KFP16023.1 - 0.08 12.8 0.2 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Docking PF08990.11 KFP16023.1 - 0.18 11.4 0.3 0.33 10.6 0.3 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking E1-E2_ATPase PF00122.20 KFP16023.1 - 0.53 9.8 4.7 0.62 9.6 0.9 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Pox_A14 PF05767.12 KFP16023.1 - 2.1 8.6 5.0 27 5.0 0.8 3.0 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.21 KFP16024.1 - 5e-45 153.9 18.6 6.7e-45 153.5 18.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP16024.1 - 0.0019 17.9 13.0 0.0019 17.9 13.0 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP16024.1 - 0.007 16.1 16.4 0.0097 15.7 16.4 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Str PF10326.9 KFP16024.1 - 0.018 14.4 21.1 1.8e+02 1.3 20.9 2.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF2975 PF11188.8 KFP16024.1 - 0.13 12.2 3.1 0.16 11.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Fibrinogen_C PF00147.18 KFP16025.1 - 5.1e-62 209.6 0.2 6.1e-62 209.3 0.2 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4625 PF15418.6 KFP16025.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Ras PF00071.22 KFP16026.1 - 3.6e-63 212.0 0.1 4.3e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16026.1 - 8.4e-35 119.6 0.1 1.4e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16026.1 - 2.6e-12 46.6 0.1 3.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP16026.1 - 3.3e-07 30.4 0.1 5.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP16026.1 - 3.4e-05 24.1 0.1 0.00046 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFP16026.1 - 6e-05 23.0 0.3 0.023 14.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP16026.1 - 8.8e-05 22.1 0.1 0.00023 20.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP16026.1 - 0.0065 16.9 0.1 0.011 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFP16026.1 - 0.0082 15.5 0.1 0.015 14.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KFP16026.1 - 0.021 14.8 0.1 0.064 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFP16026.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFP16026.1 - 0.03 14.8 0.4 0.051 14.1 0.4 1.8 1 1 0 1 1 1 0 ABC transporter FAD-SLDH PF12318.8 KFP16026.1 - 0.046 13.8 0.2 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FeoB_N PF02421.18 KFP16026.1 - 0.049 13.2 0.1 0.16 11.5 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KFP16026.1 - 0.075 12.4 0.1 0.24 10.8 0.1 2.1 1 1 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 KFP16026.1 - 0.087 12.6 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFP16026.1 - 0.15 11.9 1.6 0.28 10.9 0.5 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RINGv PF12906.7 KFP16027.1 - 3e-15 56.0 7.1 3e-15 56.0 7.1 2.8 4 0 0 4 4 4 1 RING-variant domain Vpu PF00558.19 KFP16027.1 - 0.011 15.5 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Vpu protein zf-RING_2 PF13639.6 KFP16027.1 - 0.017 15.5 6.4 0.017 15.5 6.4 2.5 3 0 0 3 3 3 0 Ring finger domain zf-ANAPC11 PF12861.7 KFP16027.1 - 0.044 13.8 0.9 0.044 13.8 0.9 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFP16027.1 - 0.42 10.8 6.3 0.47 10.7 2.3 2.8 2 1 1 3 3 3 0 FANCL C-terminal domain Ran_BP1 PF00638.18 KFP16028.1 - 9.5e-14 51.7 0.0 1.7e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SDF PF00375.18 KFP16029.1 - 1.3e-132 442.6 28.9 1.5e-132 442.3 28.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SPACA7 PF15307.6 KFP16029.1 - 0.12 12.6 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 DUF2207 PF09972.9 KFP16029.1 - 8.9 4.9 14.1 0.03 13.1 0.3 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Lon_C PF05362.13 KFP16030.1 - 3.2e-25 88.9 0.0 1e-24 87.2 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KFP16030.1 - 8.3e-25 87.7 0.0 3.6e-24 85.7 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KFP16030.1 - 4.3e-24 85.6 7.9 4.3e-24 85.6 7.9 2.3 3 1 0 3 3 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KFP16030.1 - 4.3e-09 36.5 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFP16030.1 - 2.8e-08 34.1 0.0 1e-07 32.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFP16030.1 - 5.9e-07 30.0 2.6 1.1e-05 25.9 0.0 3.3 3 1 1 4 4 3 1 AAA ATPase domain RuvB_N PF05496.12 KFP16030.1 - 6.4e-07 29.3 0.0 1.4e-05 24.9 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 KFP16030.1 - 2.9e-06 26.5 0.0 5.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KFP16030.1 - 3.7e-05 24.0 1.5 0.0011 19.3 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KFP16030.1 - 0.00052 20.1 0.3 0.0031 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFP16030.1 - 0.0014 18.9 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Acetate_kinase PF00871.17 KFP16030.1 - 0.0017 17.2 0.9 0.0026 16.5 0.9 1.3 1 0 0 1 1 1 1 Acetokinase family IstB_IS21 PF01695.17 KFP16030.1 - 0.0017 18.1 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein LXG PF04740.12 KFP16030.1 - 0.0089 15.8 1.2 0.14 11.8 0.3 3.0 3 0 0 3 3 3 1 LXG domain of WXG superfamily AAA_24 PF13479.6 KFP16030.1 - 0.018 14.8 0.4 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFP16030.1 - 0.02 14.1 0.7 0.078 12.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KFP16030.1 - 0.02 14.8 0.2 0.066 13.1 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase NACHT PF05729.12 KFP16030.1 - 0.021 14.7 0.0 0.1 12.5 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 KFP16030.1 - 0.024 14.5 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP16030.1 - 0.026 15.1 0.0 0.026 15.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KFP16030.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFP16030.1 - 0.038 14.1 0.1 0.2 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Peptidase_S41_N PF11918.8 KFP16030.1 - 0.042 14.1 3.9 1.7 8.9 0.0 3.7 4 0 0 4 4 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP AAA_7 PF12775.7 KFP16030.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KFP16030.1 - 0.054 14.0 0.6 0.57 10.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 KFP16030.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KFP16030.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFP16030.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.3 2 2 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KFP16030.1 - 0.2 11.6 10.8 0.62 9.9 0.0 3.9 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KFP16030.1 - 0.48 10.5 1.5 1.9 8.5 0.0 2.7 4 1 0 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 KFP16030.1 - 0.76 10.2 0.0 0.76 10.2 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KFP16030.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.9 2 1 0 2 2 1 0 AAA domain Lon_C PF05362.13 KFP16031.1 - 1.3e-40 139.1 0.0 1.4e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 KFP16031.1 - 6.3e-08 32.5 0.0 7.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Ribosomal_L36e PF01158.18 KFP16032.1 - 2.5e-37 127.0 6.3 2.8e-37 126.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Filament PF00038.21 KFP16033.1 - 8.3e-85 285.1 46.2 1.1e-84 284.7 46.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFP16033.1 - 2.9e-18 66.2 0.4 6.3e-18 65.2 0.4 1.6 1 0 0 1 1 1 1 Lamin Tail Domain BRE1 PF08647.11 KFP16033.1 - 0.0012 18.9 5.7 0.0012 18.9 5.7 3.9 1 1 1 3 3 3 2 BRE1 E3 ubiquitin ligase DUF1326 PF07040.11 KFP16033.1 - 0.34 10.9 1.5 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) FPP PF05911.11 KFP16033.1 - 0.35 9.0 42.1 0.078 11.2 2.3 3.0 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 KFP16033.1 - 0.36 10.9 26.3 2.8 8.0 3.8 5.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KFP16033.1 - 0.48 9.2 45.8 5.2 5.9 15.0 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein PspB PF06667.12 KFP16033.1 - 0.61 10.2 5.8 0.13 12.4 0.9 2.7 2 0 0 2 2 2 0 Phage shock protein B FlaC_arch PF05377.11 KFP16033.1 - 1.4 9.4 16.1 5.5 7.5 0.1 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF1844 PF08899.11 KFP16033.1 - 1.5 9.2 9.1 3.6 8.0 0.6 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1844) Baculo_PEP_C PF04513.12 KFP16033.1 - 2.7 8.0 7.1 8.8 6.4 0.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KFP16033.1 - 9.5 6.6 6.6 29 5.0 1.0 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_A22B PF04258.13 KFP16034.1 - 3.9e-85 285.8 15.4 5.3e-85 285.4 15.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFP16034.1 - 2e-08 34.1 0.0 4.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF4079 PF13301.6 KFP16034.1 - 0.085 13.0 2.7 0.095 12.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4181 PF13789.6 KFP16034.1 - 6.8 7.0 8.9 2.1 8.7 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4181) LSM PF01423.22 KFP16035.1 - 2.3e-21 75.3 0.0 2.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Kelch_6 PF13964.6 KFP16036.1 - 8.7e-23 79.8 15.0 4.9e-06 26.6 0.1 6.5 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFP16036.1 - 3.3e-22 77.8 16.9 0.00016 21.2 0.0 7.0 6 1 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP16036.1 - 5.4e-22 77.8 1.6 1.3e-21 76.6 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP16036.1 - 5.3e-09 35.9 8.0 0.38 10.8 0.0 6.2 4 2 2 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP16036.1 - 1.1e-08 34.7 8.0 0.1 12.6 0.1 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KFP16036.1 - 3e-08 33.8 4.1 0.048 14.0 0.0 5.1 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP16036.1 - 1.6e-06 28.0 7.3 0.28 11.2 0.1 5.6 6 0 0 6 6 6 2 Kelch motif BTB PF00651.31 KFP16036.1 - 8.6e-06 26.0 0.1 1.4e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain TRAM_LAG1_CLN8 PF03798.16 KFP16037.1 - 1.1e-42 146.0 26.1 1.5e-42 145.6 26.1 1.2 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFP16037.1 - 5.2e-06 26.2 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain Myosin_head PF00063.21 KFP16038.1 - 9.9e-246 817.2 0.0 1.3e-245 816.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFP16038.1 - 6.7e-16 56.5 28.5 0.00019 20.9 1.7 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP16038.1 - 0.011 16.0 0.1 0.038 14.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP16038.1 - 0.024 15.0 0.0 0.22 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 KFP16038.1 - 0.21 10.5 0.1 0.35 9.8 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain CheR_N PF03705.15 KFP16038.1 - 0.63 9.8 3.5 1.6 8.5 1.7 2.7 3 0 0 3 3 3 0 CheR methyltransferase, all-alpha domain MBD_C PF14048.6 KFP16039.1 - 6.5e-36 122.9 0.4 1.2e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa PF16564.5 KFP16039.1 - 6.7e-31 106.3 0.8 1.4e-30 105.3 0.8 1.5 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD MBD PF01429.19 KFP16039.1 - 1.9e-08 33.9 0.2 0.00024 20.7 0.0 2.3 2 0 0 2 2 2 2 Methyl-CpG binding domain RasGAP PF00616.19 KFP16039.1 - 0.01 15.6 0.1 0.016 14.9 0.1 1.4 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase NUMOD1 PF07453.13 KFP16039.1 - 0.19 12.0 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain RNA_pol_3_Rpc31 PF11705.8 KFP16039.1 - 2.5 8.3 10.3 0.65 10.2 7.3 1.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 UCR_6-4kD PF08997.10 KFP16040.1 - 1e-18 67.0 2.1 1.1e-18 66.9 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 KFP16040.1 - 7.8e-05 22.7 2.8 0.00064 19.7 2.8 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HLH PF00010.26 KFP16041.1 - 2.2e-09 37.2 2.8 5.3e-09 35.9 2.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFP16041.1 - 0.22 9.8 9.3 0.3 9.3 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KFP16041.1 - 7 5.1 5.4 10 4.5 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ephrin PF00812.17 KFP16046.1 - 4.5e-45 153.0 0.4 4.6e-44 149.8 0.1 2.0 2 0 0 2 2 2 1 Ephrin TMEM132D_C PF15706.5 KFP16046.1 - 0.0016 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RIFIN PF02009.16 KFP16046.1 - 0.034 14.0 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 KFP16046.1 - 0.057 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KFP16046.1 - 0.058 14.3 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KFP16046.1 - 0.082 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Amnionless ECSCR PF15820.5 KFP16046.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Stevor PF17410.2 KFP16046.1 - 0.13 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame UL45 PF05473.12 KFP16046.1 - 0.18 11.4 0.0 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF4381 PF14316.6 KFP16046.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ARGLU PF15346.6 KFP16047.1 - 4.5e-52 175.9 58.7 4.5e-52 175.9 58.7 3.0 1 1 0 2 2 2 1 Arginine and glutamate-rich 1 Ion_trans_2 PF07885.16 KFP16051.1 - 5.5e-33 112.8 17.8 2.4e-17 62.6 0.3 2.9 3 0 0 3 3 3 2 Ion channel DUF2070 PF09843.9 KFP16051.1 - 0.041 12.2 0.0 0.041 12.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) IclR PF01614.18 KFP16051.1 - 0.18 11.6 0.3 0.46 10.3 0.1 1.6 2 0 0 2 2 2 0 Bacterial transcriptional regulator Dapper PF15268.6 KFP16053.1 - 2.8e-226 754.2 31.6 3.9e-225 750.4 31.6 1.9 1 1 0 1 1 1 1 Dapper TALPID3 PF15324.6 KFP16054.1 - 0 1581.2 78.1 0 1346.3 43.0 2.6 2 1 1 3 3 3 2 Hedgehog signalling target ESP PF16590.5 KFP16054.1 - 2.2 8.6 8.0 1.1 9.6 3.2 2.8 3 0 0 3 3 3 0 Exocrine gland-secreting peptide FlgN PF05130.12 KFP16054.1 - 3.4 8.2 20.1 0.28 11.7 8.4 3.3 3 1 0 3 3 3 0 FlgN protein zf-Tim10_DDP PF02953.15 KFP16055.1 - 1.4e-17 63.1 3.5 1.8e-17 62.7 3.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 KFP16055.1 - 0.027 14.4 0.9 0.04 13.9 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RBB1NT PF08169.11 KFP16056.1 - 4.7e-37 126.0 2.8 5.1e-37 125.9 0.3 2.6 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.21 KFP16056.1 - 1.1e-20 74.1 0.1 2.3e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KFP16056.1 - 1.8e-13 50.2 1.9 8.3e-13 48.0 2.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tudor_2 PF18104.1 KFP16056.1 - 0.0089 15.7 0.0 0.037 13.7 0.0 2.1 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain PWWP PF00855.17 KFP16056.1 - 0.01 16.2 0.0 0.01 16.2 0.0 4.3 4 1 0 4 4 4 0 PWWP domain Tudor_3 PF18115.1 KFP16056.1 - 0.039 13.8 0.2 15 5.5 0.0 2.8 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Proteasome PF00227.26 KFP16057.1 - 8.7e-54 181.9 0.1 1.1e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP16057.1 - 2e-14 52.9 0.1 3.5e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 KFP16057.1 - 0.0023 16.7 0.0 0.51 9.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5018) Actin PF00022.19 KFP16058.1 - 5.2e-43 147.2 0.0 1e-40 139.6 0.0 2.5 1 1 0 1 1 1 1 Actin DUF4696 PF15767.5 KFP16059.1 - 1e-130 437.1 66.9 1.7e-130 436.4 66.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4696) Voldacs PF03517.13 KFP16059.1 - 0.0027 17.9 4.1 0.0098 16.0 4.1 2.0 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF4611 PF15387.6 KFP16059.1 - 0.0032 17.7 9.5 0.0032 17.7 9.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KFP16059.1 - 0.0056 14.8 10.9 0.008 14.3 10.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 KFP16059.1 - 0.033 12.4 10.4 0.051 11.8 10.4 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KFP16059.1 - 0.044 14.0 13.1 0.1 12.8 13.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 VID27_N PF17748.1 KFP16059.1 - 0.26 11.1 5.2 0.49 10.2 5.2 1.3 1 0 0 1 1 1 0 VID27 N-terminal region Paf1 PF03985.13 KFP16059.1 - 0.32 10.0 11.1 0.58 9.1 11.1 1.3 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 KFP16059.1 - 0.34 10.1 7.7 0.042 13.0 3.3 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 KFP16059.1 - 0.65 9.4 12.3 0.034 13.6 6.6 1.7 2 0 0 2 2 2 0 SDA1 Pox_Ag35 PF03286.14 KFP16059.1 - 0.9 9.3 8.4 2.7 7.8 8.4 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 KFP16059.1 - 0.91 8.8 10.5 0.042 13.2 3.9 2.0 2 0 0 2 2 2 0 BUD22 RPN2_C PF18004.1 KFP16059.1 - 1.1 9.2 6.1 2.9 7.8 6.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Astro_capsid_p PF12226.8 KFP16059.1 - 4.4 6.4 13.1 7.8 5.5 13.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sigma70_ner PF04546.13 KFP16059.1 - 5.1 6.9 12.3 11 5.9 12.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Radial_spoke PF04712.12 KFP16059.1 - 5.2 5.9 13.6 11 4.8 13.6 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Nucleo_P87 PF07267.11 KFP16059.1 - 5.6 5.7 4.8 9.7 4.9 4.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Phage_Gp23 PF10669.9 KFP16059.1 - 6.3 7.2 10.9 11 6.3 10.9 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HSP90 PF00183.18 KFP16059.1 - 7.2 5.4 9.4 11 4.7 9.4 1.2 1 0 0 1 1 1 0 Hsp90 protein FAM176 PF14851.6 KFP16059.1 - 7.5 6.2 11.8 1.9 8.2 8.1 1.9 2 0 0 2 2 1 0 FAM176 family CDC45 PF02724.14 KFP16059.1 - 8.3 4.6 10.8 13 4.0 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 KFP16059.1 - 8.9 6.0 8.0 18 5.0 8.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Ferlin_C PF16165.5 KFP16059.1 - 9.1 6.2 6.1 17 5.3 0.1 2.4 2 0 0 2 2 2 0 Ferlin C-terminus RRN3 PF05327.11 KFP16059.1 - 9.6 4.6 9.8 17 3.8 9.6 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ADP_ribosyl_GH PF03747.14 KFP16061.1 - 6e-54 183.7 0.1 6.9e-54 183.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Cullin_binding PF03556.15 KFP16062.1 - 6.6e-38 129.8 0.6 6.6e-38 129.8 0.6 2.0 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KFP16062.1 - 3.3e-09 36.4 2.7 4.3e-09 36.1 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain Na_H_Exchanger PF00999.21 KFP16063.1 - 6.2e-71 239.2 41.9 8.1e-71 238.8 41.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_36 PF17167.4 KFP16063.1 - 0.16 10.6 0.2 0.26 9.9 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF16 PF01519.16 KFP16063.1 - 9.7 6.7 7.6 12 6.5 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DP PF08781.10 KFP16064.1 - 3.4e-64 214.9 2.1 3.4e-64 214.9 2.1 1.8 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.20 KFP16064.1 - 7.5e-27 93.2 0.1 1.7e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain LMBR1 PF04791.16 KFP16064.1 - 0.28 10.1 2.3 0.29 10.0 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Na_K-ATPase PF00287.18 KFP16065.1 - 3.7e-87 292.1 0.4 4.5e-87 291.8 0.4 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Na_K-ATPase PF00287.18 KFP16066.1 - 4.1e-27 95.1 0.6 4.5e-27 95.0 0.6 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain FAM70 PF14967.6 KFP16067.1 - 1.2e-163 544.3 4.2 1.4e-163 544.1 4.2 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.6 KFP16067.1 - 0.00041 20.6 12.4 0.0052 17.0 6.7 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Phage_holin_3_2 PF04550.12 KFP16067.1 - 0.12 12.9 4.5 0.32 11.5 0.6 2.4 2 0 0 2 2 2 0 Phage holin family 2 DUF2407_C PF13373.6 KFP16067.1 - 1.4 9.1 2.4 6.7 6.9 1.0 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain Laminin_G_1 PF00054.23 KFP16069.1 - 7e-30 103.9 0.0 9.8e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFP16069.1 - 4.2e-27 95.2 0.0 1.2e-13 51.8 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.15 KFP16069.1 - 1.5e-21 76.3 53.5 4.5e-08 33.2 7.5 4.9 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.7 KFP16069.1 - 2.6e-17 62.4 32.0 7.4e-09 35.4 4.1 4.9 4 0 0 4 4 4 3 Complement Clr-like EGF-like Gla PF00594.20 KFP16069.1 - 1.4e-16 60.4 10.3 1.4e-16 60.4 10.3 1.8 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.6 KFP16069.1 - 2.1e-12 47.1 59.9 2e-07 31.2 11.2 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP16069.1 - 6.6e-10 39.1 45.9 3.1e-06 27.3 5.6 4.9 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFP16069.1 - 7.4e-05 23.2 34.1 0.032 14.9 1.7 5.3 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_3 PF12947.7 KFP16069.1 - 0.00078 19.6 52.3 0.0085 16.3 5.2 4.7 4 0 0 4 4 4 2 EGF domain C2 PF00168.30 KFP16070.1 - 7.2e-36 122.6 0.1 2.6e-17 63.0 0.0 3.4 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFP16070.1 - 6.5e-30 104.4 0.1 5.8e-19 68.6 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KFP16070.1 - 6.4e-15 55.6 1.9 1.7e-14 54.2 0.4 2.4 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFP16070.1 - 1e-13 50.8 5.8 2e-13 49.9 5.8 1.5 1 0 0 1 1 1 1 BTK motif PH_9 PF15410.6 KFP16070.1 - 0.011 16.1 0.1 0.047 14.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 KFP16070.1 - 0.015 15.5 0.1 0.048 14.0 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain ANAPC3 PF12895.7 KFP16073.1 - 1.8e-28 98.6 16.4 1.1e-20 73.6 10.1 5.6 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP16073.1 - 1.2e-23 81.2 17.9 0.00015 21.6 0.1 10.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP16073.1 - 1.5e-22 78.4 16.8 4.9e-08 32.5 0.2 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP16073.1 - 8.2e-18 64.5 11.9 4.5e-10 39.7 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP16073.1 - 1.5e-16 59.1 7.3 0.0017 18.4 0.0 7.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFP16073.1 - 2.6e-13 49.0 5.9 1.5e-05 24.7 0.1 4.9 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP16073.1 - 7.4e-12 44.7 1.8 0.00047 19.9 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFP16073.1 - 4.5e-09 36.1 0.1 1.2 9.7 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP16073.1 - 4.5e-09 35.9 1.7 3.6e-06 26.6 0.0 4.7 5 1 0 5 5 4 1 TPR repeat TPR_19 PF14559.6 KFP16073.1 - 6e-09 36.3 4.9 0.36 11.4 3.7 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP16073.1 - 2.5e-08 34.4 7.7 0.13 13.0 0.0 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP16073.1 - 5.9e-07 29.5 0.2 0.073 13.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP16073.1 - 8.6e-06 26.2 11.5 3.8 8.6 0.0 7.4 5 3 3 8 8 7 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFP16073.1 - 0.012 15.6 8.4 0.16 12.0 2.0 3.5 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_3 PF07720.12 KFP16073.1 - 0.028 14.4 2.0 7.2 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP16073.1 - 0.06 14.0 13.0 1.2 9.9 0.5 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP16073.1 - 0.27 11.4 7.9 1.4 9.1 0.3 4.2 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF5113 PF17140.4 KFP16073.1 - 7.2 6.4 11.7 3 7.6 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF5113) Smg4_UPF3 PF03467.15 KFP16074.1 - 2.8e-49 167.5 0.1 2.8e-49 167.5 0.1 3.2 2 1 0 2 2 2 1 Smg-4/UPF3 family zf-H2C2_2 PF13465.6 KFP16075.1 - 0.0024 18.2 0.8 0.0024 18.2 0.8 5.3 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP16075.1 - 0.011 16.5 0.1 0.011 16.5 0.1 5.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP16075.1 - 0.088 12.6 0.0 0.088 12.6 0.0 4.8 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP16075.1 - 0.13 12.8 0.1 0.13 12.8 0.1 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Septin PF00735.18 KFP16078.1 - 6.2e-95 317.7 0.5 6.2e-95 317.7 0.5 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP16078.1 - 2.8e-05 24.1 0.0 8.6e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP16078.1 - 0.00028 21.3 0.1 0.00077 19.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFP16078.1 - 0.00042 20.3 0.2 0.062 13.2 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KFP16078.1 - 0.0012 19.1 0.1 0.0064 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFP16078.1 - 0.002 17.7 2.4 1.1 8.8 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP16078.1 - 0.0037 16.8 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 KFP16078.1 - 0.0046 16.7 0.1 0.0092 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 KFP16078.1 - 0.0074 16.5 0.0 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RHD3 PF05879.12 KFP16078.1 - 0.0098 14.1 0.2 0.0098 14.1 0.2 2.5 3 0 0 3 3 3 1 Root hair defective 3 GTP-binding protein (RHD3) Microtub_bd PF16796.5 KFP16078.1 - 0.012 15.6 0.9 0.067 13.1 0.0 2.6 3 0 0 3 3 3 0 Microtubule binding ABC_tran PF00005.27 KFP16078.1 - 0.012 16.2 0.2 0.037 14.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.20 KFP16078.1 - 0.017 14.3 7.7 0.043 13.0 0.1 3.1 2 1 0 3 3 3 0 G-protein alpha subunit Dynamin_N PF00350.23 KFP16078.1 - 0.024 14.7 0.0 0.024 14.7 0.0 2.3 2 1 0 2 2 2 0 Dynamin family T2SSE PF00437.20 KFP16078.1 - 0.026 13.6 0.0 0.064 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AIG1 PF04548.16 KFP16078.1 - 0.051 12.9 2.1 0.073 12.4 0.0 2.1 2 0 0 2 2 2 0 AIG1 family IIGP PF05049.13 KFP16078.1 - 0.068 12.2 5.1 0.19 10.8 0.0 2.7 2 1 1 3 3 3 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KFP16078.1 - 0.097 12.0 0.1 0.097 12.0 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KFP16078.1 - 0.56 10.3 0.0 0.56 10.3 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 KFP16078.1 - 1.5 9.3 17.6 0.67 10.4 1.7 2.7 2 1 0 2 2 2 0 AAA domain SID-1_RNA_chan PF13965.6 KFP16079.1 - 0.036 12.5 0.3 0.048 12.1 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 KFP16079.1 - 0.095 11.7 0.5 0.14 11.2 0.5 1.1 1 0 0 1 1 1 0 CLN3 protein KI67R PF08065.12 KFP16079.1 - 0.9 10.1 6.0 0.46 11.1 2.9 2.0 2 0 0 2 2 2 0 KI67R (NUC007) repeat OAD_gamma PF04277.13 KFP16079.1 - 1.4 9.6 10.1 21 5.8 10.1 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TNFR_c6 PF00020.18 KFP16079.1 - 1.5 9.3 22.9 0.054 13.9 8.1 3.7 1 1 2 4 4 4 0 TNFR/NGFR cysteine-rich region Orf78 PF06024.12 KFP16079.1 - 9.1 6.6 7.3 2.3 8.6 2.1 2.4 1 1 2 3 3 3 0 Orf78 (ac78) bZIP_1 PF00170.21 KFP16081.1 - 0.00085 19.4 4.9 0.00085 19.4 4.9 3.3 3 0 0 3 3 3 1 bZIP transcription factor NPV_P10 PF05531.12 KFP16081.1 - 0.0015 19.0 5.3 0.0015 18.9 1.0 2.6 2 1 1 3 3 2 1 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 KFP16081.1 - 0.0017 17.5 14.7 0.0017 17.5 14.7 1.4 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc42p PF11544.8 KFP16081.1 - 0.0084 16.1 6.2 0.0084 16.1 6.2 2.7 3 1 0 3 3 2 1 Spindle pole body component Spc42p HALZ PF02183.18 KFP16081.1 - 0.009 16.2 1.2 0.009 16.2 1.2 3.5 3 1 1 4 4 4 1 Homeobox associated leucine zipper DHR10 PF18595.1 KFP16081.1 - 0.013 15.6 12.8 0.013 15.6 12.8 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4600 PF15372.6 KFP16081.1 - 0.022 15.2 5.7 0.022 15.2 5.7 3.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4600) RACo_linker PF17650.1 KFP16081.1 - 0.036 13.9 1.4 0.17 11.8 0.2 2.2 1 1 1 2 2 2 0 RACo linker region FapA PF03961.13 KFP16081.1 - 0.12 10.9 11.0 0.16 10.5 11.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lipase_chap PF03280.14 KFP16081.1 - 0.18 11.7 12.7 0.31 11.0 12.7 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein RVT_connect PF06815.13 KFP16081.1 - 0.26 11.6 3.8 0.36 11.1 0.1 2.5 1 1 0 2 2 2 0 Reverse transcriptase connection domain DASH_Dam1 PF08653.10 KFP16081.1 - 0.33 10.8 2.1 1.1 9.1 0.2 2.5 2 1 0 3 3 3 0 DASH complex subunit Dam1 DUF87 PF01935.17 KFP16081.1 - 0.53 10.3 7.6 0.5 10.4 5.9 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain FUSC PF04632.12 KFP16081.1 - 0.59 8.6 3.2 0.84 8.1 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KFP16081.1 - 0.8 9.7 8.9 0.25 11.4 4.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CorA PF01544.18 KFP16081.1 - 0.84 8.9 10.3 0.94 8.7 7.9 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Rootletin PF15035.6 KFP16081.1 - 0.85 9.6 23.3 0.2 11.6 19.2 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 KFP16081.1 - 1.1 7.1 12.4 1.3 6.8 12.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 KFP16081.1 - 1.4 8.1 15.2 0.15 11.3 8.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein Phage_GPO PF05929.11 KFP16081.1 - 1.5 8.4 10.6 2.2 7.9 10.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3450 PF11932.8 KFP16081.1 - 2 7.7 17.6 0.032 13.5 7.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GvpL_GvpF PF06386.11 KFP16081.1 - 2.2 8.2 9.1 1.3 8.9 7.0 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF5595 PF18077.1 KFP16081.1 - 2.2 8.4 8.5 15 5.8 0.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) CREPT PF16566.5 KFP16081.1 - 3.3 7.9 18.3 7 6.8 8.0 3.1 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour ING PF12998.7 KFP16081.1 - 7.3 7.3 14.6 0.14 12.8 5.3 2.6 2 1 1 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding TMF_TATA_bd PF12325.8 KFP16081.1 - 7.4 6.8 21.5 0.06 13.6 10.5 2.7 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding UPF0449 PF15136.6 KFP16081.1 - 7.8 7.0 13.1 11 6.5 2.0 3.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 ATG11 PF10377.9 KFP16081.1 - 7.9 6.6 11.9 4 7.5 1.2 3.3 1 1 2 3 3 3 0 Autophagy-related protein 11 Pro_isomerase PF00160.21 KFP16082.1 - 9.8e-42 142.9 0.6 1.1e-41 142.8 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KFP16083.1 - 7.4e-09 35.1 0.1 1.3e-05 24.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP16083.1 - 8.9e-08 31.6 0.1 4.4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP16083.1 - 7.9e-07 29.4 0.1 0.0024 18.5 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP16083.1 - 0.00023 21.3 0.5 0.079 13.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP16083.1 - 0.0023 18.0 0.1 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP16083.1 - 0.0064 17.0 0.3 3.1 8.4 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP16083.1 - 0.017 15.1 0.1 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP16083.1 - 0.029 14.5 0.0 0.13 12.4 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP16083.1 - 0.044 13.7 0.3 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP16083.1 - 0.053 13.2 0.1 0.36 10.5 0.0 2.4 2 1 1 3 3 3 0 TPR repeat TPR_16 PF13432.6 KFP16083.1 - 0.1 13.2 0.0 23 5.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 KFP16083.1 - 0.14 12.9 0.2 25 5.7 0.0 2.7 2 1 0 2 2 2 0 Sel1 repeat LIM PF00412.22 KFP16084.1 - 1.3e-62 207.8 62.3 1.7e-14 53.8 3.0 5.1 5 0 0 5 5 5 5 LIM domain zf-RRN7 PF11781.8 KFP16084.1 - 0.29 10.9 0.1 0.29 10.9 0.1 8.9 10 1 0 10 10 10 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rab_bind PF16704.5 KFP16085.1 - 7.7e-38 128.4 8.4 7.7e-38 128.4 8.4 9.4 10 4 1 11 11 11 1 Rab binding domain GRIP PF01465.20 KFP16085.1 - 4.1e-17 61.8 0.7 1.4e-16 60.1 0.3 2.3 2 0 0 2 2 2 1 GRIP domain HOOK PF05622.12 KFP16085.1 - 0.00011 20.6 47.9 0.00011 20.6 47.9 8.9 1 1 5 7 7 7 1 HOOK protein ZapB PF06005.12 KFP16085.1 - 0.0011 19.4 10.8 0.0011 19.4 10.8 26.6 5 5 14 19 19 19 3 Cell division protein ZapB DUF3772 PF12607.8 KFP16085.1 - 3 7.7 8.4 6 6.7 0.5 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) Sulfotransfer_1 PF00685.27 KFP16086.1 - 5.6e-93 311.3 3.1 6.5e-93 311.1 3.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP16086.1 - 1.5e-07 32.0 0.2 1.1e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family DUF1447 PF07288.11 KFP16086.1 - 0.062 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) SSF PF00474.17 KFP16088.1 - 2.9e-33 115.3 29.1 4.2e-33 114.8 29.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Glyco_transf_29 PF00777.18 KFP16094.1 - 2.4e-37 128.8 0.0 5.3e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) 7tm_1 PF00001.21 KFP16095.1 - 1.4e-25 90.1 10.3 1.6e-25 90.0 10.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP16095.1 - 3.1e-05 23.5 5.7 4.2e-05 23.0 5.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.13 KFP16095.1 - 3.2e-05 23.2 0.6 3.7e-05 23.0 0.6 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF2975 PF11188.8 KFP16095.1 - 0.0034 17.2 3.1 0.0047 16.8 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) BCD PF15461.6 KFP16095.1 - 0.0041 16.6 2.3 0.0041 16.6 2.3 1.4 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase UbiA PF01040.18 KFP16095.1 - 0.007 15.7 6.5 0.01 15.1 6.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HemY_N PF07219.13 KFP16095.1 - 0.76 10.0 3.9 1.7 8.9 0.1 2.3 1 1 1 2 2 2 0 HemY protein N-terminus DUF1201 PF06716.11 KFP16095.1 - 6.3 6.9 12.2 0.41 10.7 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) GDP_Man_Dehyd PF16363.5 KFP16096.1 - 7.7e-56 189.9 0.0 3.2e-55 187.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFP16096.1 - 2.6e-50 171.2 0.0 3.9e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UXS1_N PF11803.8 KFP16096.1 - 3.5e-24 85.0 0.1 7.7e-24 83.9 0.1 1.6 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal NAD_binding_4 PF07993.12 KFP16096.1 - 2.3e-10 40.1 0.3 3.1e-06 26.6 0.0 2.6 2 1 0 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 KFP16096.1 - 5.8e-10 38.7 0.0 8.2e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFP16096.1 - 4.5e-09 35.7 0.0 3.9e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFP16096.1 - 2.2e-08 33.6 0.2 0.0002 20.6 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein SH3_1 PF00018.28 KFP16097.1 - 6.8e-42 140.9 10.7 6.3e-14 51.3 0.1 4.7 5 0 0 5 5 5 3 SH3 domain SH3_9 PF14604.6 KFP16097.1 - 1.2e-39 134.0 3.8 1.7e-14 53.4 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KFP16097.1 - 1.1e-27 95.5 5.9 1.8e-09 37.2 0.2 4.4 4 1 1 5 5 5 3 Variant SH3 domain SH2 PF00017.24 KFP16097.1 - 3.3e-22 78.4 0.0 6.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.11 KFP16097.1 - 5.6e-09 36.2 10.8 0.0029 17.9 0.5 3.8 4 0 0 4 4 4 3 Bacterial SH3 domain SH3_10 PF17902.1 KFP16097.1 - 3.6e-07 30.1 3.5 0.0014 18.7 0.3 3.0 3 0 0 3 3 3 2 SH3 domain hSH3 PF14603.6 KFP16097.1 - 2.2e-05 24.8 0.0 0.0071 16.7 0.0 2.6 2 0 0 2 2 2 1 Helically-extended SH3 domain SH2_2 PF14633.6 KFP16097.1 - 0.0051 16.2 0.1 0.025 14.0 0.1 1.8 1 1 0 1 1 1 1 SH2 domain DUF5350 PF17299.2 KFP16097.1 - 0.074 13.5 2.8 0.96 10.0 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5350) SH3_4 PF06347.13 KFP16097.1 - 0.84 9.5 4.1 16 5.5 0.8 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain LIM PF00412.22 KFP16098.1 - 1.1e-47 160.1 69.4 7e-13 48.6 7.4 5.1 5 0 0 5 5 5 5 LIM domain Sgf11 PF08209.11 KFP16098.1 - 0.16 11.6 0.3 0.16 11.6 0.3 9.3 11 0 0 11 11 11 0 Sgf11 (transcriptional regulation protein) Ashwin PF15323.6 KFP16099.1 - 8.9e-76 254.8 11.4 9.9e-76 254.7 11.4 1.0 1 0 0 1 1 1 1 Developmental protein Vps39_2 PF10367.9 KFP16100.1 - 5.2e-30 104.1 0.0 1.3e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KFP16100.1 - 2.8e-27 95.1 8.5 1.1e-26 93.3 1.6 3.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KFP16100.1 - 1.1e-13 51.3 13.3 3.8e-08 33.3 4.7 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 KFP16100.1 - 2.3e-12 47.1 0.4 5e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 CNH domain PXA PF02194.15 KFP16100.1 - 0.078 12.9 0.3 0.18 11.7 0.3 1.7 1 0 0 1 1 1 0 PXA domain TPR_2 PF07719.17 KFP16100.1 - 6 7.2 7.2 5.3 7.4 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.19 KFP16101.1 - 8.4e-36 123.2 0.1 1.5e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Claudin_2 PF13903.6 KFP16105.1 - 3.2e-47 160.8 5.4 3.6e-47 160.6 5.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4538 PF15061.6 KFP16105.1 - 0.29 10.9 9.6 3.7 7.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Phage_holin_3_6 PF07332.11 KFP16105.1 - 1.4 9.0 16.6 0.97 9.5 6.4 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3139 PF11337.8 KFP16105.1 - 2.4 8.9 4.9 19 6.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) MFS_1 PF07690.16 KFP16106.1 - 3e-40 138.2 24.5 3.7e-40 137.9 24.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP16106.1 - 9.8e-08 31.3 7.9 9.8e-08 31.3 7.9 2.9 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KFP16106.1 - 2.6e-05 23.3 13.4 0.00014 20.9 13.4 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 KFP16106.1 - 6e-05 22.5 5.7 6e-05 22.5 5.7 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Na_H_Exchanger PF00999.21 KFP16107.1 - 5.2e-68 229.6 36.7 1.1e-56 192.3 22.7 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KFP16108.1 - 1.4e-82 277.5 36.9 1.7e-82 277.3 36.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFP16108.1 - 1e-29 103.1 1.6 1.1e-29 102.9 0.2 1.8 2 0 0 2 2 2 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Tim17 PF02466.19 KFP16108.1 - 0.0095 16.3 0.9 0.029 14.8 0.0 2.3 3 1 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family Halogen_Hydrol PF10112.9 KFP16108.1 - 0.21 11.6 2.1 0.67 10.0 1.3 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TIR PF01582.20 KFP16109.1 - 1.7e-37 128.9 0.0 3.5e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ig_6 PF18452.1 KFP16109.1 - 1.3e-25 88.7 0.2 2.2e-21 75.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP16109.1 - 5.4e-15 55.8 1.1 2.5e-06 28.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP16109.1 - 8.6e-13 48.3 2.4 6.6e-05 23.0 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain TIR_2 PF13676.6 KFP16109.1 - 7.5e-10 39.4 0.0 1.9e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain I-set PF07679.16 KFP16109.1 - 1.6e-09 37.7 3.5 0.00056 19.9 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP16109.1 - 4.2e-07 30.2 2.1 0.017 15.4 0.7 3.3 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFP16109.1 - 0.0003 21.1 1.1 0.92 9.9 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin C1-set domain Ig_5 PF16681.5 KFP16109.1 - 0.021 15.2 6.1 0.99 9.9 0.2 4.0 3 1 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP16109.1 - 0.64 10.3 9.6 0.15 12.4 0.9 3.9 3 2 1 4 4 4 0 T-cell surface glycoprotein CD3 delta chain TIR PF01582.20 KFP16110.1 - 2e-37 128.7 1.9 3.7e-37 127.8 0.0 2.2 2 1 0 2 2 2 1 TIR domain Ig_6 PF18452.1 KFP16110.1 - 2.9e-12 45.9 0.1 1.1e-05 24.9 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP16110.1 - 3.2e-11 43.4 3.1 8.6e-07 29.2 0.6 3.1 4 0 0 4 4 4 2 Immunoglobulin domain TIR_2 PF13676.6 KFP16110.1 - 7.1e-09 36.3 0.0 1.7e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFP16110.1 - 5.5e-08 33.3 6.8 0.00061 20.3 0.7 4.0 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 KFP16110.1 - 1.1e-05 25.5 6.4 0.092 12.9 0.1 4.4 3 2 1 4 4 4 2 Immunoglobulin V-set domain ig PF00047.25 KFP16110.1 - 9.3e-05 22.5 6.3 1.5 9.1 0.4 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Ig_5 PF16681.5 KFP16110.1 - 0.0004 20.7 6.5 0.0012 19.3 0.8 3.0 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP16110.1 - 0.00088 19.5 0.9 0.00088 19.5 0.9 2.4 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 KFP16110.1 - 0.00098 19.2 6.6 0.4 10.8 0.2 3.9 4 1 0 4 4 4 2 Immunoglobulin I-set domain TIR PF01582.20 KFP16111.1 - 2e-32 112.4 0.2 3e-32 111.8 0.2 1.2 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.6 KFP16111.1 - 2e-18 66.5 1.3 4.8e-07 30.0 0.2 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 KFP16111.1 - 3.2e-18 66.1 3.2 3.2e-07 30.9 0.0 3.7 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.25 KFP16111.1 - 1.8e-14 53.6 10.1 4.5e-06 26.8 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KFP16111.1 - 4.9e-14 52.2 1.3 1.7e-05 24.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP16111.1 - 2.1e-12 46.4 0.4 1.5e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP16111.1 - 8.1e-09 35.6 2.1 0.63 10.2 0.0 4.7 4 1 0 4 4 4 3 Immunoglobulin V-set domain TIR_2 PF13676.6 KFP16111.1 - 0.00021 21.8 0.0 0.00047 20.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain V-set_CD47 PF08204.11 KFP16111.1 - 0.016 15.2 0.4 0.31 11.0 0.0 2.9 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFP16111.1 - 0.034 14.4 3.6 6.7 7.1 0.1 3.6 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain BiPBP_C PF06832.12 KFP16111.1 - 0.052 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family RP853 PF17542.2 KFP16111.1 - 0.064 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized RP853 C2-set_2 PF08205.12 KFP16111.1 - 0.1 12.7 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain TIR PF01582.20 KFP16112.1 - 7.6e-33 113.8 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFP16112.1 - 4.5e-22 78.4 0.3 2.2e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP16112.1 - 4.3e-18 65.4 2.0 1e-07 32.2 0.2 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP16112.1 - 8.6e-18 64.2 0.5 3e-05 24.0 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 KFP16112.1 - 2.6e-12 46.7 0.2 0.024 14.8 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP16112.1 - 1.8e-11 43.4 0.6 2.3e-09 36.7 0.2 2.6 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP16112.1 - 1.2e-06 28.7 9.2 0.044 13.9 0.4 5.2 3 2 1 4 4 4 2 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 KFP16112.1 - 0.014 15.1 4.1 0.024 14.4 0.4 3.2 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Lep_receptor_Ig PF06328.11 KFP16112.1 - 0.016 15.1 0.6 2 8.4 0.0 3.7 4 0 0 4 4 4 0 Ig-like C2-type domain TIR_2 PF13676.6 KFP16112.1 - 0.07 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 TIR domain TIR PF01582.20 KFP16114.1 - 4e-36 124.4 0.1 5.9e-36 123.9 0.1 1.2 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.6 KFP16114.1 - 1.1e-15 58.0 0.0 0.00053 20.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP16114.1 - 1.5e-13 50.8 1.1 1.7e-06 28.3 0.1 3.0 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP16114.1 - 3.3e-13 49.5 0.0 0.0002 21.4 0.1 3.4 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP16114.1 - 1.4e-12 47.0 0.1 4.4e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP16114.1 - 2e-10 40.7 0.4 0.00061 19.9 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP16114.1 - 2.9e-07 30.6 5.5 0.1 12.8 0.5 4.5 3 2 2 5 5 5 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP16114.1 - 0.0038 17.3 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain TIR_2 PF13676.6 KFP16114.1 - 0.0056 17.3 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain ANF_receptor PF01094.28 KFP16114.1 - 0.04 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region C2-set PF05790.15 KFP16114.1 - 0.048 13.8 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Arm-DNA-bind_2 PF12167.8 KFP16114.1 - 0.049 13.5 0.9 1.5 8.8 0.1 2.9 3 0 0 3 3 3 0 Arm DNA-binding domain Ig_3 PF13927.6 KFP16116.1 - 1.4e-17 64.0 0.0 0.00047 20.7 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP16116.1 - 1.1e-16 60.9 0.0 1.8e-05 24.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP16116.1 - 8.9e-15 54.0 0.0 6.8e-12 44.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP16116.1 - 7.2e-13 48.5 0.1 0.001 19.2 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP16116.1 - 1e-12 47.9 0.0 0.00032 20.7 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 KFP16116.1 - 6.1e-11 42.5 0.9 0.0055 16.9 0.1 4.5 4 1 0 4 4 4 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP16116.1 - 0.0038 17.6 1.3 2.1 8.8 0.0 4.1 3 3 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP16116.1 - 0.0058 16.9 0.0 1.5 9.1 0.0 3.3 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain NCBP3 PF10309.9 KFP16116.1 - 0.035 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Izumo-Ig PF16706.5 KFP16116.1 - 0.044 13.9 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain CNH PF00780.22 KFP16117.1 - 3.1e-60 204.1 0.0 5.8e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP16117.1 - 6.1e-55 186.4 0.5 1.3e-54 185.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16117.1 - 1.2e-40 139.4 0.0 2.6e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RFX_DNA_binding PF02257.15 KFP16120.1 - 7.9e-18 64.9 0.1 7.9e-18 64.9 0.1 2.6 2 1 1 3 3 3 1 RFX DNA-binding domain zf-RING_2 PF13639.6 KFP16122.1 - 6.1e-13 48.9 8.1 9.6e-13 48.3 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP16122.1 - 1.7e-10 40.5 3.1 3.3e-10 39.5 3.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP16122.1 - 9.2e-10 38.2 7.7 1.5e-09 37.5 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP16122.1 - 9.5e-08 31.8 7.3 1.6e-07 31.1 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP16122.1 - 2.9e-07 30.3 5.0 4.5e-07 29.7 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP16122.1 - 4.6e-07 30.0 8.6 4.6e-07 30.0 8.6 1.8 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP16122.1 - 6.7e-07 29.1 5.0 1.1e-06 28.3 5.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP16122.1 - 5.5e-06 26.3 5.0 9.6e-06 25.5 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP16122.1 - 7.7e-05 22.5 4.8 0.00012 21.9 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CrgA PF06781.12 KFP16122.1 - 0.0013 18.8 0.7 0.0024 17.9 0.7 1.4 1 0 0 1 1 1 1 Cell division protein CrgA PspB PF06667.12 KFP16122.1 - 0.0054 16.8 1.3 0.0086 16.1 0.2 1.9 2 0 0 2 2 2 1 Phage shock protein B zf-C3H2C3 PF17122.5 KFP16122.1 - 0.011 15.7 4.4 0.029 14.4 4.4 1.8 1 1 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 KFP16122.1 - 0.019 15.0 4.6 0.041 13.9 4.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP16122.1 - 0.026 14.1 5.8 0.12 12.1 6.1 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type CDC24_OB3 PF17244.2 KFP16122.1 - 0.043 13.5 0.2 0.052 13.2 0.2 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 RINGv PF12906.7 KFP16122.1 - 0.48 10.6 3.7 1.1 9.5 3.7 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KFP16122.1 - 1 9.6 3.8 3.8 7.8 3.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KFP16122.1 - 1.8 8.8 5.6 16 5.8 6.1 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 KFP16122.1 - 2 8.3 6.2 1.6 8.7 4.7 1.7 2 0 0 2 2 1 0 PHD-finger CNOT11 PF10155.9 KFP16123.1 - 3.3e-55 185.6 6.3 5e-55 185.0 6.3 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Ribosomal_L31e PF01198.19 KFP16125.1 - 2.5e-53 178.2 1.0 3.3e-53 177.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 KFP16125.1 - 0.0067 16.3 0.1 0.014 15.2 0.0 1.6 1 1 1 2 2 2 1 DNA mismatch endonuclease Vsr PAS_11 PF14598.6 KFP16126.1 - 1.9e-20 73.1 0.8 1.2e-19 70.5 0.0 2.7 4 0 0 4 4 4 1 PAS domain PAS_3 PF08447.12 KFP16126.1 - 1.3e-16 60.7 0.1 9.7e-15 54.6 0.1 2.5 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KFP16126.1 - 4.3e-11 42.8 0.0 8.9e-08 32.1 0.0 2.8 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP16126.1 - 1.8e-09 37.4 0.4 3.8e-09 36.4 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP16126.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain Phosducin PF02114.16 KFP16127.1 - 8.7e-18 64.2 1.2 1.1e-17 63.8 0.9 1.3 1 1 0 1 1 1 1 Phosducin UPF0175 PF03683.13 KFP16127.1 - 0.0024 17.6 3.5 0.0025 17.5 0.6 2.5 4 0 0 4 4 4 1 Uncharacterised protein family (UPF0175) DUF3886 PF13025.6 KFP16127.1 - 0.025 14.8 6.3 0.025 14.8 6.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) GOLD_2 PF13897.6 KFP16127.1 - 0.41 11.1 2.1 0.36 11.3 0.7 1.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Aim21 PF11489.8 KFP16127.1 - 0.43 9.4 3.7 0.57 9.0 3.7 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 Histone_H2A_C PF16211.5 KFP16128.1 - 1.8e-15 56.4 0.7 2.6e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 KFP16128.1 - 1.7e-13 51.1 0.0 2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16128.1 - 0.00015 22.0 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KFP16129.1 - 2.2e-16 59.3 0.4 3.3e-16 58.7 0.4 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFP16129.1 - 1e-12 48.5 0.0 1.1e-12 48.4 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16129.1 - 0.00017 21.8 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sulfotransfer_2 PF03567.14 KFP16130.1 - 1.3e-51 176.0 0.1 1.6e-51 175.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family SLC3A2_N PF16028.5 KFP16130.1 - 0.031 13.8 0.7 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF1075 PF06388.11 KFP16130.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) ArgoMid PF16487.5 KFP16132.1 - 0.038 14.2 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 Mid domain of argonaute LON_substr_bdg PF02190.16 KFP16133.1 - 8.8e-23 81.3 0.0 1.5e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFP16133.1 - 9.1e-11 41.4 15.8 2.3e-10 40.1 15.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP16133.1 - 7.9e-10 38.4 9.5 1.5e-09 37.6 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP16133.1 - 2.4e-07 30.7 8.3 2.4e-07 30.7 8.3 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP16133.1 - 3e-07 30.2 14.7 7.4e-07 28.9 14.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP16133.1 - 9.1e-07 29.1 14.8 9.1e-07 29.1 14.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP16133.1 - 5.6e-06 26.4 13.3 1.3e-05 25.2 13.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFP16133.1 - 7.7e-06 25.7 11.7 1.6e-05 24.7 11.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP16133.1 - 8.5e-06 25.6 13.4 1.8e-05 24.6 13.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 KFP16133.1 - 0.00085 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 KFP16133.1 - 0.0014 18.8 10.4 0.0036 17.5 10.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFP16133.1 - 0.0022 18.1 8.0 0.0046 17.1 8.0 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFP16133.1 - 0.04 13.8 6.4 0.084 12.8 6.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFP16133.1 - 0.043 13.6 9.2 0.11 12.3 9.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AF-4 PF05110.13 KFP16135.1 - 3.1e-73 247.6 17.4 6.1e-48 163.8 3.6 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein BRD4_CDT PF17105.5 KFP16135.1 - 1.2 8.8 3.4 2.3 7.9 3.4 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 IMS PF00817.20 KFP16138.1 - 1.2e-42 145.5 0.0 2.2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFP16138.1 - 2.7e-15 57.1 0.0 5.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 KFP16138.1 - 5.5e-14 52.3 0.7 1e-13 51.4 0.7 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT_2 PF16589.5 KFP16138.1 - 3.7e-10 40.1 0.0 9.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFP16138.1 - 3.2e-08 33.8 0.0 7.8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UBM PF14377.6 KFP16138.1 - 3e-07 29.7 4.7 0.0074 15.7 0.2 2.7 2 0 0 2 2 2 2 Ubiquitin binding region LIG3_BRCT PF16759.5 KFP16138.1 - 7.3e-07 29.4 0.0 2.2e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KFP16138.1 - 0.00013 22.1 0.0 0.015 15.6 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 KFP16138.1 - 0.00035 20.4 0.0 0.0009 19.2 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain mCpol PF18182.1 KFP16138.1 - 0.017 15.4 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Cdd1 PF11731.8 KFP16138.1 - 0.019 15.2 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 KFP16138.1 - 0.085 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Thioredoxin PF00085.20 KFP16139.1 - 3.2e-11 43.1 0.1 6.6e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KFP16139.1 - 7.3e-09 34.9 0.4 9.7e-09 34.5 0.4 1.1 1 0 0 1 1 1 1 Phosducin Sds3 PF08598.11 KFP16139.1 - 0.022 14.8 3.3 0.15 12.0 4.6 1.7 2 0 0 2 2 2 0 Sds3-like eIF-3_zeta PF05091.12 KFP16139.1 - 0.028 13.4 0.8 0.036 13.0 0.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BAG PF02179.16 KFP16139.1 - 0.1 13.0 6.1 0.22 12.0 6.1 1.5 1 0 0 1 1 1 0 BAG domain FapA PF03961.13 KFP16139.1 - 1.9 7.0 6.0 2.2 6.8 6.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SLT PF01464.20 KFP16140.1 - 0.0029 17.3 0.0 0.006 16.2 0.0 1.6 2 0 0 2 2 2 1 Transglycosylase SLT domain RVT_1 PF00078.27 KFP16141.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SLT PF01464.20 KFP16142.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT PF01464.20 KFP16143.1 - 3.6e-06 26.6 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Ribosomal_L30 PF00327.20 KFP16144.1 - 2.3e-13 49.8 1.2 3.4e-13 49.3 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MIT_C PF16565.5 KFP16145.1 - 6.7e-57 191.4 0.0 1.1e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 KFP16145.1 - 0.0012 18.8 1.7 0.0029 17.7 1.7 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain VSG_B PF13206.6 KFP16145.1 - 0.48 9.6 2.0 0.63 9.2 2.0 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain BPL_LplA_LipB PF03099.19 KFP16146.1 - 0.00074 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4121 PF13497.6 KFP16146.1 - 0.025 13.7 0.1 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) Neuregulin PF02158.15 KFP16148.1 - 2.9e-156 520.4 36.7 3.9e-156 520.0 36.7 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region I-set PF07679.16 KFP16148.1 - 1.2e-14 54.2 0.8 6e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP16148.1 - 5.5e-12 46.1 1.1 1.8e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP16148.1 - 4.1e-10 39.7 1.5 8e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP16148.1 - 6.3e-09 36.0 0.3 2.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP16148.1 - 3.3e-06 27.2 0.3 3.5e-05 23.9 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain C1-set PF07654.15 KFP16148.1 - 0.00031 21.1 1.3 0.00082 19.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.12 KFP16148.1 - 0.0014 18.7 1.1 0.013 15.5 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain EGF PF00008.27 KFP16148.1 - 0.0018 18.5 3.8 0.0035 17.6 3.8 1.5 1 0 0 1 1 1 1 EGF-like domain DUF973 PF06157.11 KFP16148.1 - 0.065 12.3 0.1 0.12 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Cyt_b-c1_8 PF10890.8 KFP16148.1 - 0.087 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 TMEM132D_C PF15706.5 KFP16148.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EGF_2 PF07974.13 KFP16148.1 - 0.7 10.3 2.7 2 8.8 2.7 1.8 1 1 0 1 1 1 0 EGF-like domain Glyco_transf_10 PF00852.19 KFP16149.1 - 2.2e-38 131.8 0.1 4.1e-38 130.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 KFP16149.1 - 1.5e-10 41.5 0.1 4.4e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal PPTA PF01239.22 KFP16150.1 - 2.6e-50 166.8 18.1 4.9e-12 45.2 0.5 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 KFP16150.1 - 0.11 12.3 11.4 2.9 7.7 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) TPR_14 PF13428.6 KFP16150.1 - 0.13 13.1 1.3 9.9 7.3 0.4 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-Di19 PF05605.12 KFP16151.1 - 3.6e-22 78.4 1.5 3.6e-22 78.4 1.5 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 KFP16151.1 - 1.1e-09 37.9 6.2 1.1e-09 37.9 6.2 2.5 3 0 0 3 3 3 1 Zinc finger, ZZ type TagA PF12561.8 KFP16151.1 - 0.00089 19.6 0.2 0.0018 18.6 0.2 1.5 1 0 0 1 1 1 1 ToxR activated gene A lipoprotein domain Dicty_REP PF05086.12 KFP16151.1 - 0.0075 14.3 4.1 0.0097 13.9 4.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein zf-C2H2 PF00096.26 KFP16151.1 - 0.0096 16.3 0.3 0.0096 16.3 0.3 3.1 3 1 0 3 3 1 1 Zinc finger, C2H2 type Di19_C PF14571.6 KFP16151.1 - 0.042 14.4 3.5 0.042 14.4 3.5 2.2 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal zinc_ribbon_9 PF14369.6 KFP16151.1 - 0.11 12.8 1.6 12 6.3 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon TFIIA PF03153.13 KFP16151.1 - 0.11 12.5 8.3 0.14 12.2 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FOXP-CC PF16159.5 KFP16151.1 - 0.29 11.8 3.7 36 5.1 0.4 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFP16151.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4407 PF14362.6 KFP16151.1 - 2 7.7 7.1 2.7 7.3 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-ribbon_3 PF13248.6 KFP16151.1 - 2.5 7.6 8.8 3.4 7.2 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain HOOK PF05622.12 KFP16152.1 - 0 1038.3 81.6 0 1038.1 81.6 1.0 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.18 KFP16152.1 - 0.0015 18.7 3.2 0.0015 18.7 3.2 8.3 9 1 1 10 10 10 2 Homeobox associated leucine zipper Spc7 PF08317.11 KFP16152.1 - 0.0026 16.7 22.7 0.0026 16.7 22.7 5.1 2 2 4 6 6 6 3 Spc7 kinetochore protein Mod_r PF07200.13 KFP16152.1 - 0.0052 16.9 20.0 0.0052 16.9 20.0 6.6 2 2 4 6 6 6 2 Modifier of rudimentary (Mod(r)) protein KASH_CCD PF14662.6 KFP16152.1 - 0.0079 16.0 8.7 0.0079 16.0 8.7 6.4 2 2 3 6 6 6 2 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 KFP16152.1 - 0.0084 16.4 9.7 0.0084 16.4 9.7 8.2 4 2 5 9 9 9 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KFP16152.1 - 0.15 12.2 103.3 0.18 11.9 23.8 6.9 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFP16152.1 - 1.6 9.1 90.0 8.1 6.8 21.7 4.8 1 1 2 3 3 3 0 Fez1 NPV_P10 PF05531.12 KFP16152.1 - 4.1 7.9 41.0 0.71 10.4 3.1 8.5 5 3 3 8 8 8 0 Nucleopolyhedrovirus P10 protein DUF1232 PF06803.12 KFP16153.1 - 5.1e-10 39.0 9.6 5.1e-10 39.0 9.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-RING_UBOX PF13445.6 KFP16153.1 - 5.4e-09 35.9 5.6 9.7e-09 35.1 2.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP16153.1 - 2.1e-08 33.9 4.1 3.5e-08 33.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP16153.1 - 2.1e-08 33.9 2.8 3e-08 33.4 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP16153.1 - 7.3e-08 32.5 5.0 1.7e-07 31.3 5.1 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP16153.1 - 1.3e-06 28.6 6.7 2.1e-06 28.0 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP16153.1 - 2.4e-06 27.3 5.3 5.6e-06 26.1 5.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP16153.1 - 1.3e-05 25.0 3.9 3.4e-05 23.6 4.0 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP16153.1 - 1.5e-05 24.9 4.7 2.9e-05 23.9 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Cys_rich_CPXG PF14255.6 KFP16153.1 - 0.0039 17.1 0.6 2.1 8.3 0.2 2.4 2 0 0 2 2 2 2 Cysteine-rich CPXCG zf-Nse PF11789.8 KFP16153.1 - 0.0071 16.1 1.0 0.013 15.3 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DpnI_C PF17726.1 KFP16153.1 - 0.022 14.8 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 Dam-replacing HTH domain zf-ANAPC11 PF12861.7 KFP16153.1 - 0.044 13.8 2.0 0.08 13.0 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KFP16153.1 - 0.12 12.5 1.2 0.23 11.6 1.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFP16153.1 - 0.7 10.2 5.9 1.7 9.0 5.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KFP16153.1 - 1.5 8.9 4.8 5.2 7.2 4.8 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain zf-WRNIP1_ubi PF18279.1 KFP16153.1 - 2.2 9.1 5.2 29 5.6 0.2 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Baculo_IE-1 PF05290.11 KFP16153.1 - 3.2 7.7 4.9 6.3 6.7 4.9 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) THAP PF05485.12 KFP16154.1 - 9.6e-12 45.7 2.6 9.6e-12 45.7 2.6 2.0 2 1 0 2 2 2 1 THAP domain Cep57_CLD PF14073.6 KFP16154.1 - 1.6e-05 25.0 2.1 2.5e-05 24.4 2.1 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 PI3K_P85_iSH2 PF16454.5 KFP16154.1 - 0.0014 18.2 7.5 0.002 17.7 7.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 KFP16154.1 - 0.002 18.3 9.0 0.0028 17.7 9.0 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 KFP16154.1 - 0.0026 16.4 2.8 0.0036 16.0 2.8 1.1 1 0 0 1 1 1 1 Macoilin family Ax_dynein_light PF10211.9 KFP16154.1 - 0.0064 16.5 6.3 0.011 15.7 6.3 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain ATG16 PF08614.11 KFP16154.1 - 0.0071 16.6 2.2 0.011 16.0 2.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4391 PF14335.6 KFP16154.1 - 0.013 15.2 2.4 0.021 14.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) GrpE PF01025.19 KFP16154.1 - 0.014 15.1 5.3 0.021 14.5 5.3 1.2 1 0 0 1 1 1 0 GrpE MPS2 PF17060.5 KFP16154.1 - 0.014 14.7 1.8 0.018 14.3 1.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF16 PF01519.16 KFP16154.1 - 0.017 15.6 4.2 0.031 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 KFP16154.1 - 0.024 14.0 6.4 0.032 13.6 6.4 1.1 1 0 0 1 1 1 0 Tropomyosin DUF573 PF04504.14 KFP16154.1 - 0.027 15.1 1.1 0.061 14.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DUF4140 PF13600.6 KFP16154.1 - 0.072 13.5 0.6 0.11 12.9 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 KFP16154.1 - 0.1 12.6 4.3 0.15 12.0 4.3 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p HGD-D PF06050.13 KFP16154.1 - 0.11 12.3 0.3 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF4407 PF14362.6 KFP16154.1 - 0.14 11.4 1.2 0.19 11.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KFP16154.1 - 0.16 12.4 2.9 0.25 11.8 2.9 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFP16154.1 - 0.19 11.5 7.7 0.33 10.8 7.7 1.3 1 0 0 1 1 1 0 Septum formation initiator YPEB PF14620.6 KFP16154.1 - 0.22 10.8 2.9 0.31 10.4 2.9 1.1 1 0 0 1 1 1 0 YpeB sporulation FliD_C PF07195.12 KFP16154.1 - 0.35 10.3 1.4 0.48 9.8 1.4 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_Xtn PF12848.7 KFP16154.1 - 0.76 9.8 9.4 1.4 9.0 9.4 1.3 1 0 0 1 1 1 0 ABC transporter Spc7 PF08317.11 KFP16154.1 - 0.92 8.3 8.1 1.3 7.8 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 KFP16154.1 - 2.7 8.3 4.4 4.1 7.7 4.4 1.2 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 KFP16154.1 - 2.7 7.8 6.1 4.7 7.0 6.1 1.4 1 0 0 1 1 1 0 USP8 interacting 4HBT_3 PF13622.6 KFP16154.1 - 3.5 7.8 4.5 4.8 7.4 4.5 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Neur_chan_LBD PF02931.23 KFP16155.1 - 2.8e-74 249.2 0.1 4.2e-74 248.6 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP16155.1 - 3.5e-65 220.4 14.9 1.3e-49 169.4 11.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 KFP16155.1 - 0.04 13.6 1.3 0.04 13.6 1.3 1.6 2 0 0 2 2 2 0 PepSY-associated TM region Glyco_hydro_39 PF01229.17 KFP16156.1 - 3.5e-148 494.2 0.0 4.3e-148 493.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sulfate_transp PF00916.20 KFP16157.1 - 1.8e-123 412.1 21.6 2.4e-123 411.7 21.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP16157.1 - 9e-26 89.8 0.0 1.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF3852 PF12963.7 KFP16157.1 - 0.62 10.4 5.8 0.24 11.8 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3852) DUF1427 PF07235.11 KFP16157.1 - 0.82 9.7 3.4 0.5 10.3 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1427) EF-hand_1 PF00036.32 KFP16158.1 - 2.4e-32 108.1 11.6 9e-10 37.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFP16158.1 - 8.8e-28 95.9 7.8 2e-13 50.0 0.1 4.0 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 KFP16158.1 - 2.5e-27 95.1 0.8 1.9e-15 57.1 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP16158.1 - 3e-21 73.5 7.5 9.9e-10 37.6 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP16158.1 - 1.8e-19 68.3 8.7 1.8e-06 27.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFP16158.1 - 2.4e-11 43.8 0.4 1.6e-09 37.9 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KFP16158.1 - 2.7e-05 24.0 0.1 0.096 12.7 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 KFP16158.1 - 0.0012 18.8 0.0 0.033 14.2 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 KFP16158.1 - 0.0032 17.6 3.1 1 9.6 0.1 2.7 2 1 0 2 2 2 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KFP16158.1 - 0.0064 16.8 0.0 0.049 13.9 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Poly_export PF02563.16 KFP16158.1 - 0.01 16.0 0.1 0.77 10.0 0.0 2.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein Caleosin PF05042.13 KFP16158.1 - 0.011 15.7 0.2 0.58 10.1 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein DUF1103 PF06513.11 KFP16158.1 - 0.026 14.1 1.5 0.031 13.9 1.5 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) TetR_C_7 PF14246.6 KFP16158.1 - 0.065 13.3 0.1 5.7 7.0 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain EFhand_Ca_insen PF08726.10 KFP16158.1 - 0.077 13.1 0.2 0.26 11.4 0.1 2.0 2 2 0 2 2 2 0 Ca2+ insensitive EF hand Fe_hyd_lg_C PF02906.14 KFP16158.1 - 0.088 12.5 0.1 0.21 11.2 0.1 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_11 PF08976.11 KFP16158.1 - 0.11 13.3 0.0 6 7.8 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain LRR_8 PF13855.6 KFP16159.1 - 3.6e-32 109.9 17.1 7.9e-13 48.0 1.7 3.5 2 1 1 3 3 3 3 Leucine rich repeat I-set PF07679.16 KFP16159.1 - 1.3e-15 57.3 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP16159.1 - 4.6e-14 52.8 0.2 9.5e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 KFP16159.1 - 7.2e-12 45.4 0.8 1e-06 28.7 0.1 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ig_2 PF13895.6 KFP16159.1 - 3.6e-11 43.3 0.0 7.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 KFP16159.1 - 1.3e-10 41.4 19.8 0.0025 18.2 4.1 4.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) ig PF00047.25 KFP16159.1 - 5.8e-09 36.0 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP16159.1 - 5.8e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.6 KFP16159.1 - 3.9e-05 23.2 7.0 0.0027 17.2 1.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.17 KFP16159.1 - 0.00081 19.5 0.1 0.67 10.1 0.0 2.4 1 1 1 2 2 2 2 Immunoglobulin V-set domain LRR_1 PF00560.33 KFP16159.1 - 0.012 16.1 13.1 3.7 8.5 0.9 6.0 6 0 0 6 6 5 0 Leucine Rich Repeat Sigma_reg_N PF13800.6 KFP16159.1 - 0.22 11.8 2.4 0.5 10.7 2.4 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3139 PF11337.8 KFP16159.1 - 0.3 11.8 3.3 0.83 10.3 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) RINGv PF12906.7 KFP16160.1 - 2.6e-15 56.3 8.0 5.1e-15 55.3 8.0 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KFP16160.1 - 0.0003 20.9 4.2 0.0003 20.9 4.2 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFP16160.1 - 0.0016 18.7 5.3 0.0031 17.8 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain DUF1139 PF06599.11 KFP16160.1 - 0.067 12.6 0.1 3 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) Bromodomain PF00439.25 KFP16161.1 - 5.4e-22 77.7 0.0 1.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain MBD PF01429.19 KFP16161.1 - 1e-13 50.8 0.1 2.5e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain WSD PF15613.6 KFP16161.1 - 8.2e-13 48.7 0.2 1.9e-07 31.4 0.1 5.6 6 0 0 6 6 6 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 KFP16161.1 - 1.2e-11 44.3 9.1 3.3e-11 42.9 9.1 1.8 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFP16161.1 - 9.9e-09 35.4 0.8 2.9e-08 33.9 0.3 2.1 2 0 0 2 2 2 1 DDT domain Nop14 PF04147.12 KFP16161.1 - 1.7e-06 26.6 12.5 1.7e-06 26.6 12.5 6.1 5 2 0 5 5 5 2 Nop14-like family WHIM1 PF15612.6 KFP16161.1 - 0.02 14.4 0.0 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 WD40 PF00400.32 KFP16162.1 - 9.2e-43 143.4 16.8 9.2e-08 32.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.15 KFP16162.1 - 4.2e-24 84.5 0.1 7.9e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.17 KFP16162.1 - 1.8e-14 53.6 0.3 3.4e-14 52.7 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP16162.1 - 5.2e-12 46.0 0.3 1.1e-11 45.0 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ANAPC4_WD40 PF12894.7 KFP16162.1 - 2.5e-11 43.7 0.0 0.039 14.3 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP16162.1 - 1e-06 28.0 2.7 0.2 10.6 0.2 4.7 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KFP16162.1 - 2.5e-06 26.1 0.0 0.053 11.8 0.1 2.4 2 1 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 KFP16162.1 - 1.2e-05 25.2 0.0 0.04 13.8 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A SAM_PNT PF02198.16 KFP16162.1 - 1.6e-05 24.8 0.1 6.8e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain zf-NOSIP PF15906.5 KFP16162.1 - 0.00026 21.1 1.1 0.0012 18.9 0.0 2.6 3 0 0 3 3 2 1 Zinc-finger of nitric oxide synthase-interacting protein ELYS-bb PF16687.5 KFP16162.1 - 0.00043 19.0 0.0 0.00074 18.2 0.0 1.3 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin SAM_3 PF18016.1 KFP16162.1 - 0.00065 19.5 0.4 0.0019 18.0 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PALB2_WD40 PF16756.5 KFP16162.1 - 0.0017 17.3 0.1 0.022 13.7 0.0 2.3 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain zf-Nse PF11789.8 KFP16162.1 - 0.0036 17.1 0.2 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF2415 PF10313.9 KFP16162.1 - 0.24 11.4 4.6 4 7.4 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) Ank_2 PF12796.7 KFP16163.1 - 1.1e-59 198.9 1.5 4.7e-15 55.9 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP16163.1 - 6.5e-43 144.6 8.3 2.6e-08 34.2 0.0 8.2 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP16163.1 - 4.9e-36 118.7 1.5 0.00068 19.9 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KFP16163.1 - 2.2e-31 106.9 12.0 0.00097 19.5 0.0 10.5 11 0 0 11 11 10 6 Ankyrin repeat Ank_5 PF13857.6 KFP16163.1 - 1e-30 105.4 7.7 1.9e-09 37.6 0.0 8.4 3 2 7 10 10 9 6 Ankyrin repeats (many copies) TPR_2 PF07719.17 KFP16163.1 - 3e-07 30.0 8.1 0.33 11.2 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP16163.1 - 1.7e-05 24.9 1.3 0.00072 19.7 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP16163.1 - 5.5e-05 23.7 2.0 0.0017 19.0 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP16163.1 - 0.00019 21.0 4.8 1.3 8.8 0.1 3.6 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 KFP16163.1 - 0.00021 21.2 3.9 0.037 14.2 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP16163.1 - 0.00058 20.3 3.4 0.25 11.9 0.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFP16163.1 - 0.0024 18.3 0.3 0.02 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TPR_1 PF00515.28 KFP16163.1 - 0.004 16.9 8.1 4.1 7.4 1.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP16163.1 - 0.0041 17.8 2.8 0.019 15.8 2.8 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP16163.1 - 0.068 13.5 0.2 0.068 13.5 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP16163.1 - 0.094 12.8 0.2 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP16163.1 - 1 9.9 5.6 3 8.4 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DAP PF15228.6 KFP16164.1 - 5.2e-11 43.6 0.4 7e-11 43.2 0.4 1.2 1 0 0 1 1 1 1 Death-associated protein Arm PF00514.23 KFP16165.1 - 3.4e-45 150.7 8.5 5.7e-10 38.9 0.0 8.7 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP16165.1 - 3.4e-06 27.4 0.1 0.042 14.2 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 KFP16165.1 - 0.00078 19.5 5.4 0.99 9.8 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KFP16165.1 - 0.001 19.6 1.5 1.4 9.5 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat EphA2_TM PF14575.6 KFP16165.1 - 2.1 9.3 3.6 5.8 7.9 2.6 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase_Tyr PF07714.17 KFP16167.1 - 1.1e-35 123.2 0.0 1.6e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP16167.1 - 1.5e-35 122.8 0.0 2.5e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TGF_beta_GS PF08515.12 KFP16167.1 - 2e-17 62.4 0.4 3.5e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.23 KFP16167.1 - 0.0019 18.1 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP16167.1 - 0.0038 16.2 0.2 0.0074 15.3 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFP16167.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TMEM154 PF15102.6 KFP16167.1 - 0.099 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family PSI_PsaJ PF01701.18 KFP16167.1 - 1.4 9.5 3.3 3.6 8.2 3.3 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ PDZ_6 PF17820.1 KFP16168.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP16168.1 - 3.8e-09 36.8 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP16168.1 - 0.003 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Ribosomal_60s PF00428.19 KFP16169.1 - 0.006 17.1 2.7 0.006 17.1 2.7 2.6 2 1 0 2 2 2 1 60s Acidic ribosomal protein Mtc PF03820.17 KFP16170.1 - 5.2e-115 383.8 0.2 5.8e-115 383.6 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF1980 PF09323.10 KFP16170.1 - 0.048 13.6 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RBD-FIP PF09457.10 KFP16171.1 - 2e-10 40.4 8.9 2e-10 40.4 8.9 2.4 2 1 0 2 2 2 1 FIP domain Alk_phosphatase PF00245.20 KFP16171.1 - 0.021 13.8 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Homeodomain PF00046.29 KFP16172.1 - 1.3e-22 79.4 3.3 2e-22 78.8 3.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KFP16173.1 - 1.7e-22 79.0 4.7 2.2e-22 78.6 4.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP16173.1 - 0.048 13.6 0.1 0.094 12.6 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain SET PF00856.28 KFP16174.1 - 1.7e-08 35.0 0.0 3.3e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFP16174.1 - 0.00014 21.8 11.4 0.00014 21.8 11.4 3.1 3 2 0 3 3 3 1 MYND finger zf-HIT PF04438.16 KFP16174.1 - 1.4 8.9 13.7 0.057 13.3 4.9 2.7 2 0 0 2 2 2 0 HIT zinc finger PA PF02225.22 KFP16175.1 - 3.7e-06 26.9 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 PA domain Cpn60_TCP1 PF00118.24 KFP16176.1 - 1.4e-22 80.0 0.0 1.5e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gar1 PF04410.14 KFP16177.1 - 2.1e-45 154.2 0.2 3.4e-45 153.6 0.2 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.21 KFP16178.1 - 2.8e-54 184.2 20.5 3.5e-54 183.9 20.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16178.1 - 7.9e-10 38.5 20.1 1.3e-09 37.9 20.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP16178.1 - 0.00037 20.2 14.9 0.00037 20.2 14.9 2.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFP16178.1 - 0.061 13.1 10.9 0.18 11.6 10.9 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 TRP PF06011.12 KFP16178.1 - 0.47 9.1 14.5 0.55 8.9 4.4 2.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel PLAC8 PF04749.17 KFP16178.1 - 0.84 10.7 8.7 1.8 9.6 0.0 3.0 3 1 0 3 3 3 0 PLAC8 family Tma16 PF11176.8 KFP16180.1 - 1.5e-46 157.9 7.1 1.8e-46 157.6 7.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 HipN PF18253.1 KFP16180.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain DapB_C PF05173.14 KFP16180.1 - 0.045 13.8 0.3 0.07 13.2 0.3 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Use1 PF09753.9 KFP16180.1 - 0.088 12.5 6.2 0.13 12.0 6.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ion_trans_N PF08412.10 KFP16180.1 - 1.3 8.6 0.0 1.3 8.6 0.0 2.9 4 0 0 4 4 4 0 Ion transport protein N-terminal RINGv PF12906.7 KFP16181.1 - 7.4e-16 58.0 15.7 1.7e-15 56.9 15.7 1.6 1 0 0 1 1 1 1 RING-variant domain TMEM192 PF14802.6 KFP16184.1 - 1.3e-84 283.0 3.0 1.4e-84 282.9 3.0 1.0 1 0 0 1 1 1 1 TMEM192 family CRAL_TRIO PF00650.20 KFP16185.1 - 5.4e-28 97.7 0.3 9.8e-28 96.9 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.26 KFP16185.1 - 3e-21 75.3 0.0 6.5e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.6 KFP16185.1 - 0.036 14.2 0.1 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Neur_chan_LBD PF02931.23 KFP16187.1 - 1.9e-52 177.8 0.0 2.5e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP16187.1 - 1.9e-40 139.4 0.2 7.1e-34 117.9 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GEMIN8 PF15348.6 KFP16189.1 - 7.2e-95 317.7 18.0 8.1e-95 317.5 18.0 1.0 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Myelin_PLP PF01275.19 KFP16190.1 - 1e-99 333.2 18.6 1.2e-99 333.0 18.6 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) PspB PF06667.12 KFP16190.1 - 0.074 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B LapA_dom PF06305.11 KFP16190.1 - 0.15 11.9 1.6 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 KFP16190.1 - 0.28 10.7 3.2 0.67 9.5 0.6 2.5 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Diphthami_syn_2 PF01902.17 KFP16191.1 - 4.6e-42 144.0 0.1 1e-41 142.9 0.1 1.5 1 1 0 1 1 1 1 Diphthamide synthase GRDB PF07355.12 KFP16191.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Aquarius_N PF16399.5 KFP16192.1 - 0 1071.7 0.3 0 1071.4 0.3 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFP16192.1 - 1.7e-26 93.1 0.0 4.3e-25 88.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFP16192.1 - 9.5e-26 91.1 0.0 8.6e-25 88.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFP16192.1 - 6.2e-07 29.8 0.0 2.7e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFP16192.1 - 2.8e-05 24.2 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFP16192.1 - 0.00038 20.2 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KFP16192.1 - 0.00089 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 UvrD_C_2 PF13538.6 KFP16192.1 - 0.0038 17.0 0.2 0.008 16.0 0.2 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KFP16192.1 - 0.0064 15.8 0.1 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KFP16192.1 - 0.0066 16.0 0.1 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 KFP16192.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 KFP16192.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF4088 PF13317.6 KFP16192.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Actin PF00022.19 KFP16193.1 - 9.6e-133 442.7 0.0 3.6e-132 440.8 0.0 1.7 1 1 0 1 1 1 1 Actin Sec3-PIP2_bind PF15277.6 KFP16194.1 - 3.7e-24 84.7 0.1 6e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.21 KFP16194.1 - 9.5e-06 25.3 0.6 9.5e-06 25.3 0.6 1.8 2 0 0 2 2 2 1 Synaptobrevin DSX_dimer PF08828.10 KFP16194.1 - 0.2 11.3 0.2 5.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Doublesex dimerisation domain Laminin_N PF00055.17 KFP16195.1 - 1e-55 188.9 0.0 1e-55 188.9 0.0 3.0 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFP16195.1 - 9.5e-23 80.1 60.9 1.7e-08 34.4 11.4 4.8 3 1 1 4 4 4 3 Laminin EGF domain EGF_2 PF07974.13 KFP16195.1 - 0.0021 18.4 10.1 0.0021 18.4 10.1 7.2 6 2 0 6 6 6 1 EGF-like domain hEGF PF12661.7 KFP16195.1 - 0.0041 17.7 8.2 0.0041 17.7 8.2 7.0 7 1 1 8 8 8 1 Human growth factor-like EGF EGF PF00008.27 KFP16195.1 - 0.0061 16.8 9.2 0.0061 16.8 9.2 6.8 6 2 0 6 6 6 1 EGF-like domain RhoGEF PF00621.20 KFP16196.1 - 5.2e-39 134.4 8.1 5.2e-39 134.4 8.1 1.7 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 KFP16196.1 - 4.6e-24 83.9 0.0 5.8e-14 51.5 0.0 2.9 3 0 0 3 3 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP16196.1 - 8.8e-18 63.7 0.1 5.5e-14 51.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP16196.1 - 1.2e-17 63.5 0.1 7.3e-11 41.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 KFP16196.1 - 2e-15 56.6 0.5 8.8e-15 54.6 0.5 2.2 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 KFP16196.1 - 1.6e-09 37.5 4.9 3.9e-09 36.3 4.9 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP16196.1 - 8.1e-08 32.7 0.1 2e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 PH domain CH PF00307.31 KFP16196.1 - 2.2e-06 27.8 0.1 1.3e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Filamin PF00630.19 KFP16196.1 - 0.0006 20.6 0.0 0.0028 18.4 0.0 2.2 1 1 0 1 1 1 1 Filamin/ABP280 repeat C1_2 PF03107.16 KFP16196.1 - 0.0049 17.2 3.6 0.015 15.6 3.6 1.9 1 0 0 1 1 1 1 C1 domain CAMSAP_CH PF11971.8 KFP16196.1 - 0.0078 16.0 1.1 0.033 14.0 0.1 2.5 2 0 0 2 2 2 1 CAMSAP CH domain LZ3wCH PF18517.1 KFP16196.1 - 0.012 15.7 2.3 0.014 15.5 0.1 2.4 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DUF2326 PF10088.9 KFP16196.1 - 0.027 14.2 0.3 5.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) Prok-RING_1 PF14446.6 KFP16196.1 - 0.038 13.9 4.2 0.1 12.6 4.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PH_10 PF15411.6 KFP16196.1 - 0.085 13.1 2.4 0.16 12.3 0.1 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain DUF2247 PF10004.9 KFP16196.1 - 0.64 9.8 5.2 2 8.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) Mito_carr PF00153.27 KFP16197.1 - 3.5e-74 244.8 4.9 3.2e-26 91.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFP16197.1 - 8.6e-16 56.2 4.0 3e-06 26.4 0.5 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFP16197.1 - 4.5e-14 52.7 1.9 2.1e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP16197.1 - 5.8e-14 50.8 4.1 0.00025 20.7 0.6 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KFP16197.1 - 1.1e-11 43.7 1.9 6.3e-05 22.3 0.4 3.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFP16197.1 - 1.4e-08 34.4 2.1 1.7e-05 24.6 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP16197.1 - 0.00019 21.7 0.8 0.0035 17.6 0.7 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFP16197.1 - 0.00097 19.0 1.2 0.53 10.2 0.2 3.1 2 1 1 3 3 3 1 EF hand DUF2340 PF10209.9 KFP16197.1 - 0.0083 16.6 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2340) EF-hand_4 PF12763.7 KFP16197.1 - 0.012 15.6 3.0 0.25 11.3 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP16197.1 - 0.013 15.7 0.0 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 KFP16197.1 - 0.018 15.3 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain B5 PF03484.15 KFP16197.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetase B5 domain DUF3764 PF12594.8 KFP16197.1 - 0.11 12.5 0.0 32 4.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) NT-C2 PF10358.9 KFP16198.1 - 1.3e-15 57.4 0.0 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Methyltransf_12 PF08242.12 KFP16199.1 - 0.018 15.7 0.0 0.048 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PRP38 PF03371.15 KFP16200.1 - 5.7e-58 195.6 0.0 7.8e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFP16200.1 - 0.0019 18.8 43.0 0.0019 18.8 43.0 3.4 1 1 2 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MCLC PF05934.11 KFP16201.1 - 1.3e-165 552.2 6.6 1.5e-165 552.0 6.6 1.0 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) DUF4149 PF13664.6 KFP16201.1 - 0.36 11.2 3.7 0.37 11.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) PAP2 PF01569.21 KFP16201.1 - 3.4 7.4 8.1 1.5 8.6 4.2 2.2 2 1 0 2 2 2 0 PAP2 superfamily DUF5582 PF17819.1 KFP16202.1 - 2.9e-25 89.4 0.0 3.9e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 KFP16202.1 - 0.0041 16.3 0.1 0.0057 15.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) RIIa PF02197.17 KFP16202.1 - 0.019 14.6 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Tetraspanin PF00335.20 KFP16203.1 - 2.7e-24 86.2 7.1 3.6e-24 85.8 7.1 1.1 1 0 0 1 1 1 1 Tetraspanin family YrvL PF14184.6 KFP16203.1 - 0.0073 16.4 1.2 0.0073 16.4 1.2 1.8 2 0 0 2 2 2 1 Regulatory protein YrvL Peptidase_M61 PF05299.12 KFP16203.1 - 0.073 13.5 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DUF3487 PF11990.8 KFP16203.1 - 0.93 9.4 3.8 0.24 11.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Glyco_transf_43 PF03360.16 KFP16204.1 - 2.9e-72 242.8 0.0 3.4e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_transf_7N PF13733.6 KFP16205.1 - 8.3e-58 193.8 0.1 1.3e-57 193.2 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP16205.1 - 5.8e-28 96.4 0.6 1.5e-27 95.1 0.6 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Phycoerythr_ab PF02972.14 KFP16205.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain Amidase PF01425.21 KFP16206.1 - 7.9e-90 302.0 0.1 6.9e-89 298.9 0.1 1.9 1 1 0 1 1 1 1 Amidase SNF2_N PF00176.23 KFP16207.1 - 1.7e-56 191.4 0.1 5.3e-56 189.8 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP16207.1 - 1.5e-11 44.6 0.0 1.9e-10 41.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP16207.1 - 3.2e-11 43.5 0.0 8.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP16207.1 - 2.9e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFP16207.1 - 0.0028 16.9 0.0 0.036 13.2 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 KFP16207.1 - 0.042 14.1 0.4 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain APH PF01636.23 KFP16207.1 - 0.16 11.9 1.4 0.84 9.5 0.5 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Strabismus PF06638.11 KFP16208.1 - 2.9e-252 837.8 0.0 3.6e-252 837.5 0.0 1.0 1 0 0 1 1 1 1 Strabismus protein CDT1_C PF16679.5 KFP16208.1 - 0.027 14.9 2.5 0.059 13.8 2.5 1.6 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Calsequestrin PF01216.17 KFP16209.1 - 6.5e-214 710.1 42.8 2.6e-213 708.1 42.8 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.6 KFP16209.1 - 5.8e-21 75.2 5.1 2e-19 70.2 2.9 2.3 2 1 0 2 2 2 2 Thioredoxin-like domain SDA1 PF05285.12 KFP16209.1 - 0.056 12.9 15.4 0.082 12.3 15.4 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KFP16209.1 - 5.2 6.3 11.0 7.3 5.8 11.0 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KFP16209.1 - 6.3 5.0 19.2 8.8 4.5 19.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 KFP16210.1 - 5e-29 101.4 14.5 7.2e-29 100.9 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP16210.1 - 3.2e-27 95.4 43.9 2.7e-24 85.7 31.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mab-21 PF03281.14 KFP16211.1 - 3.8e-83 279.2 5.4 5.6e-83 278.6 5.4 1.2 1 0 0 1 1 1 1 Mab-21 protein Cation_ATPase_C PF00689.21 KFP16212.1 - 1.7e-44 151.7 0.3 1.7e-44 151.7 0.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFP16212.1 - 3.3e-44 150.6 0.7 3.3e-44 150.6 0.7 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFP16212.1 - 5.8e-24 84.0 0.0 1.3e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP16212.1 - 8.9e-19 68.6 0.3 3.2e-09 37.4 0.0 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP16212.1 - 3.6e-17 61.8 0.0 6.9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFP16212.1 - 6.7e-06 26.0 1.1 0.00084 19.2 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ig_3 PF13927.6 KFP16213.1 - 1.8e-07 31.7 0.0 0.0062 17.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP16213.1 - 4.3e-06 26.9 0.1 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFP16213.1 - 7.7e-06 26.0 0.1 0.09 13.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP16213.1 - 0.00039 20.4 0.1 0.036 14.1 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin I-set domain Receptor_2B4 PF11465.8 KFP16213.1 - 0.001 19.3 0.2 0.012 15.8 0.0 2.2 2 1 0 2 2 2 1 Natural killer cell receptor 2B4 Ig_5 PF16681.5 KFP16213.1 - 0.018 15.4 3.0 0.13 12.7 0.1 2.5 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.6 KFP16213.1 - 0.02 15.2 0.2 0.33 11.3 0.1 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Herpes_gE PF02480.16 KFP16213.1 - 0.042 12.6 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Lipase PF00151.19 KFP16214.1 - 1.1e-99 333.9 0.0 1.3e-99 333.7 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFP16214.1 - 0.0015 19.2 1.7 0.0022 18.7 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFP16214.1 - 0.058 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP16214.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Popeye PF04831.13 KFP16215.1 - 1.9e-50 170.7 0.1 2.3e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 KFP16215.1 - 0.0025 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CAP_N PF01213.19 KFP16215.1 - 0.22 11.0 0.6 0.28 10.6 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Phage_holin_3_6 PF07332.11 KFP16215.1 - 1.8 8.6 3.4 3.3 7.8 3.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM208_SND2 PF05620.11 KFP16215.1 - 2.2 8.0 4.2 3.6 7.3 4.2 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 CFAP91 PF14738.6 KFP16216.1 - 3.5e-65 218.7 10.8 3.5e-65 218.7 10.8 3.9 3 1 0 3 3 3 1 Cilia- and flagella-associated protein 91 DUF5624 PF18538.1 KFP16216.1 - 0.027 14.6 1.7 0.073 13.2 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) DUF5607 PF18355.1 KFP16216.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Pkinase PF00069.25 KFP16217.1 - 4.6e-69 232.7 0.0 5.4e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16217.1 - 2e-24 86.3 0.0 2.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP16217.1 - 3.7e-05 23.2 0.0 0.00032 20.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFP16217.1 - 0.0045 17.0 0.1 0.014 15.4 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP16217.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFP16217.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 KFP16217.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase 7tm_3 PF00003.22 KFP16218.1 - 6.1e-40 137.4 19.2 8.2e-40 137.0 19.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NYD-SP28 PF14772.6 KFP16218.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Sperm tail LRR_4 PF12799.7 KFP16219.1 - 3.8e-16 58.9 18.8 1.1e-07 32.0 0.1 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP16219.1 - 2.6e-15 55.9 8.9 1.5e-11 43.9 6.2 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KFP16219.1 - 0.00014 21.9 13.6 1.3 9.9 0.0 5.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP16219.1 - 0.0002 20.9 0.6 0.0004 19.9 0.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeat Kazal_2 PF07648.15 KFP16220.1 - 1.5e-13 50.6 5.9 1.5e-13 50.6 5.9 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KFP16220.1 - 1.1e-06 28.6 1.9 1.1e-06 28.6 1.9 2.4 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain Kazal_1 PF00050.21 KFP16220.1 - 1.5e-06 28.1 9.6 4.8e-06 26.5 9.6 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Pacifastin_I PF05375.13 KFP16220.1 - 0.00057 19.5 9.1 0.00057 19.5 9.1 2.7 3 1 1 4 4 4 1 Pacifastin inhibitor (LCMII) EF-hand_7 PF13499.6 KFP16220.1 - 0.014 15.8 1.2 0.15 12.6 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair Hormone_3 PF00159.18 KFP16220.1 - 0.034 14.2 0.2 0.079 13.0 0.2 1.7 1 0 0 1 1 1 0 Pancreatic hormone peptide NDUF_B4 PF07225.12 KFP16221.1 - 3.8e-29 101.1 0.0 4e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HgmA PF04209.13 KFP16222.1 - 1e-222 739.4 0.0 1.1e-222 739.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Roc PF08477.13 KFP16223.1 - 4.7e-11 42.9 0.0 2.5e-10 40.6 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP16223.1 - 7.4e-09 35.4 0.0 2.7e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP16223.1 - 0.0029 17.7 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFP16223.1 - 0.12 11.8 0.1 0.4 10.1 0.1 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family TFIIE_alpha PF02002.17 KFP16224.1 - 8.5e-36 122.0 0.6 1.5e-35 121.2 0.6 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFP16224.1 - 2.2e-30 104.8 5.8 7.3e-30 103.1 5.8 2.0 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFP16224.1 - 9.1e-12 44.3 1.0 1.8e-11 43.3 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFP16224.1 - 0.051 13.5 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 KFP16224.1 - 0.13 12.3 0.4 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PyrI_C PF02748.15 KFP16224.1 - 0.37 10.7 1.6 1.3 9.0 1.8 1.9 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KFP16224.1 - 0.98 10.4 3.0 5.9 8.0 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger LLGL PF08366.13 KFP16225.1 - 8.5e-35 119.2 0.2 1.4e-33 115.3 0.0 2.5 2 0 0 2 2 2 1 LLGL2 WD40 PF00400.32 KFP16225.1 - 4.9e-11 43.0 1.7 0.14 13.1 0.1 6.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16225.1 - 1.3e-08 35.0 0.2 0.62 10.4 0.0 6.7 3 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 KFP16225.1 - 3.8e-06 25.9 0.0 8e-05 21.5 0.0 2.9 3 1 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.21 KFP16225.1 - 0.0012 18.6 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin ELYS-bb PF16687.5 KFP16225.1 - 0.0046 15.6 0.0 0.45 9.1 0.0 2.8 2 1 1 3 3 3 1 beta-propeller of ELYS nucleoporin Frtz PF11768.8 KFP16225.1 - 0.015 13.6 0.0 0.034 12.5 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 KFP16225.1 - 0.029 13.6 0.0 2.8 7.1 0.0 2.8 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Methyltransf_10 PF05971.12 KFP16226.1 - 7e-114 380.2 0.0 1.1e-113 379.5 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KFP16226.1 - 1.7e-05 24.5 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFP16226.1 - 0.00026 20.5 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF4630 PF15443.6 KFP16226.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) MANEC PF07502.14 KFP16226.1 - 0.23 11.8 2.6 0.3 11.4 1.2 1.9 2 0 0 2 2 2 0 MANEC domain Death PF00531.22 KFP16227.1 - 1.1e-18 67.2 0.1 2e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.18 KFP16227.1 - 7.7e-17 61.4 58.3 3.1e-09 37.1 11.3 4.9 5 1 0 5 5 5 4 TNFR/NGFR cysteine-rich region NinF PF05810.12 KFP16227.1 - 2.1 8.3 10.7 0.063 13.2 2.6 2.6 2 1 0 2 2 2 0 NinF protein CTC1 PF15489.6 KFP16228.1 - 3.2e-51 174.0 2.0 3.5e-51 173.9 2.0 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 DUF3338 PF11819.8 KFP16228.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) V-set PF07686.17 KFP16229.1 - 2.9e-10 40.3 0.0 1.8e-08 34.5 0.0 3.0 3 1 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP16229.1 - 7.3e-10 39.3 0.1 0.00019 22.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP16229.1 - 3.4e-07 30.2 1.0 0.0013 18.8 0.0 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP16229.1 - 4e-06 27.1 0.7 0.11 12.9 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP16229.1 - 1.2e-05 25.4 1.1 0.00066 19.8 0.0 3.0 2 2 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP16229.1 - 0.0017 18.3 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP16229.1 - 0.017 15.5 0.1 0.32 11.4 0.1 2.4 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP16229.1 - 0.019 14.5 0.0 0.68 9.6 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain EpuA PF11772.8 KFP16229.1 - 0.1 12.3 1.0 0.19 11.4 1.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Filamin PF00630.19 KFP16230.1 - 1.1e-18 67.9 0.1 1.8e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.24 KFP16230.1 - 2.8e-11 43.4 3.6 2.8e-11 43.4 3.6 3.0 4 0 0 4 4 4 1 B-box zinc finger Laminin_II PF06009.12 KFP16230.1 - 0.017 15.1 0.3 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain II Y_Y_Y PF07495.13 KFP16230.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain CENP-Q PF13094.6 KFP16230.1 - 0.72 10.0 0.0 0.72 10.0 0.0 2.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit SPICE PF15678.5 KFP16231.1 - 1.6e-160 535.0 27.8 1.6e-160 535.0 27.8 2.1 2 0 0 2 2 2 1 Centriole duplication and mitotic chromosome congression DUF3926 PF13080.6 KFP16231.1 - 0.042 13.8 0.6 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Acetyltransf_1 PF00583.25 KFP16232.1 - 3.5e-14 53.0 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFP16232.1 - 1.4e-09 38.2 0.1 1.9e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFP16232.1 - 6.4e-09 35.8 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP16232.1 - 1.9e-05 24.8 0.1 2.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP16232.1 - 0.0002 21.2 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFP16232.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFP16232.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFP16232.1 - 0.026 15.2 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KFP16232.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain ATP-synt_ab PF00006.25 KFP16233.1 - 8.2e-103 342.6 0.0 1e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Zn_ribbon_SprT PF17283.2 KFP16234.1 - 0.008 16.1 6.8 0.13 12.2 0.9 3.3 3 0 0 3 3 3 1 SprT-like zinc ribbon domain Yippee-Mis18 PF03226.14 KFP16234.1 - 0.0087 16.3 1.0 0.074 13.3 1.0 2.2 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 KFP16234.1 - 0.066 13.3 0.1 0.29 11.2 0.1 1.9 1 1 0 1 1 1 0 SelR domain DZR PF12773.7 KFP16234.1 - 0.17 12.0 5.0 7.5 6.7 5.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon NTP_transf_7 PF07984.12 KFP16235.1 - 2.7e-155 516.4 0.7 3.2e-155 516.2 0.7 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase CRAL_TRIO_2 PF13716.6 KFP16236.1 - 1.3e-32 112.8 1.6 2.2e-32 112.1 1.6 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 KFP16236.1 - 1.1e-27 96.4 0.0 2.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.20 KFP16236.1 - 9.8e-07 28.6 0.6 2.5e-06 27.3 0.6 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain Epimerase_2 PF02350.19 KFP16236.1 - 0.059 12.2 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase WD40 PF00400.32 KFP16237.1 - 2.3e-57 189.6 18.5 5.9e-09 36.4 0.1 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 KFP16237.1 - 6.3e-21 74.7 0.6 1.5e-20 73.5 0.6 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFP16237.1 - 4.8e-20 71.6 5.1 0.00021 21.6 0.0 9.0 4 3 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP16237.1 - 1.7e-08 34.2 0.0 0.0021 17.5 0.0 4.0 3 1 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KFP16237.1 - 1.5e-06 27.4 1.2 4.2 6.2 0.0 6.8 4 2 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFP16237.1 - 0.0035 16.2 2.0 1.3 7.7 0.2 3.6 5 0 0 5 5 5 2 Nup133 N terminal like Nup160 PF11715.8 KFP16237.1 - 0.039 12.6 1.6 6.6 5.2 0.0 4.2 5 0 0 5 5 5 0 Nucleoporin Nup120/160 R3H-assoc PF13902.6 KFP16237.1 - 4.7 7.6 7.4 23 5.4 2.7 2.6 2 0 0 2 2 2 0 R3H-associated N-terminal domain PapD-like PF14874.6 KFP16238.1 - 3.4e-09 36.8 0.0 5.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like tRNA-synt_1b PF00579.25 KFP16239.1 - 2.1e-68 230.8 0.0 2.6e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Occludin_ELL PF07303.13 KFP16239.1 - 0.059 14.1 0.1 3 8.6 0.0 2.3 2 0 0 2 2 2 0 Occludin homology domain CopC PF04234.12 KFP16239.1 - 0.13 13.3 0.1 0.23 12.5 0.1 1.4 1 0 0 1 1 1 0 CopC domain FMN_dh PF01070.18 KFP16240.1 - 1.8e-130 435.1 0.0 2.5e-130 434.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFP16240.1 - 4.5e-08 32.5 1.4 2.8e-07 29.9 0.7 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFP16240.1 - 1.6e-05 24.2 0.1 2.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KFP16240.1 - 0.001 18.6 0.2 0.0043 16.5 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KFP16240.1 - 0.014 14.7 0.4 0.34 10.2 0.1 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 KFP16240.1 - 0.027 13.9 0.0 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 KFP16240.1 - 0.044 13.2 0.8 0.07 12.5 0.8 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 KFP16240.1 - 0.056 12.7 0.1 0.11 11.7 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Glyco_hydro_47 PF01532.20 KFP16241.1 - 2.1e-157 524.7 0.0 2.6e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Apolipoprotein PF01442.18 KFP16241.1 - 1.3 8.9 5.2 0.98 9.3 2.9 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ig PF00047.25 KFP16242.1 - 1.4e-06 28.3 0.6 0.086 13.0 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.6 KFP16242.1 - 1.5e-06 28.7 0.6 0.0031 18.1 0.1 2.5 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP16242.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP16242.1 - 0.00034 20.8 1.9 0.0014 18.7 0.2 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.16 KFP16242.1 - 0.00058 19.9 0.1 0.0088 16.1 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain C1-set PF07654.15 KFP16242.1 - 0.037 14.4 0.5 0.44 11.0 0.0 2.5 2 1 0 2 2 2 0 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP16242.1 - 0.045 13.3 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain ANF_receptor PF01094.28 KFP16243.1 - 1.3e-108 363.3 0.0 1.6e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP16243.1 - 4.2e-65 219.8 30.9 8e-65 218.9 30.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP16243.1 - 1.5e-17 63.3 11.9 4.2e-17 61.9 11.9 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP16243.1 - 3.3e-12 46.7 0.0 1.6e-10 41.2 0.0 2.7 2 1 0 2 2 2 1 Periplasmic binding protein Ephrin_rec_like PF07699.13 KFP16243.1 - 0.018 14.8 8.8 0.058 13.2 8.8 1.9 1 0 0 1 1 1 0 Putative ephrin-receptor like DUF2614 PF11023.8 KFP16243.1 - 1.5 8.9 6.4 0.3 11.2 0.8 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Cystatin PF00031.21 KFP16244.1 - 9.7e-16 57.8 0.4 1.1e-15 57.7 0.4 1.0 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.21 KFP16245.1 - 4.2e-20 71.8 0.1 4.8e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFP16245.1 - 0.0074 16.6 0.1 0.0089 16.4 0.1 1.2 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Baculo_VP91_N PF08475.10 KFP16245.1 - 0.023 14.4 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Cid2 PF09774.9 KFP16246.1 - 4.7e-13 49.9 5.5 1.6e-11 44.9 5.5 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF5344 PF17279.2 KFP16246.1 - 0.016 15.8 0.5 0.023 15.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Orbi_VP5 PF00901.17 KFP16246.1 - 0.058 11.8 0.8 0.058 11.8 0.8 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 FOXP-CC PF16159.5 KFP16246.1 - 0.75 10.5 6.6 10 6.9 0.3 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF1075 PF06388.11 KFP16247.1 - 1.2e-49 167.4 0.1 1.5e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.23 KFP16248.1 - 3.2e-88 287.4 17.5 1.8e-13 50.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP16248.1 - 7.7e-27 93.6 6.6 1.5e-26 92.7 6.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KFP16248.1 - 2e-23 81.7 2.1 3.5e-23 80.9 0.7 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KFP16248.1 - 2e-17 63.3 0.0 8.1e-07 29.3 0.0 4.8 2 1 4 6 6 5 5 HEAT repeats HEAT_EZ PF13513.6 KFP16248.1 - 1.3e-13 51.1 7.1 2.3e-05 24.8 0.0 5.9 4 2 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 KFP16248.1 - 2.1e-11 43.0 6.9 0.0024 18.0 0.0 7.6 9 1 0 9 9 8 3 HEAT repeat V-ATPase_H_C PF11698.8 KFP16248.1 - 1.9e-05 24.8 0.3 0.092 12.9 0.1 4.0 3 3 1 4 4 4 3 V-ATPase subunit H RICTOR_V PF14668.6 KFP16248.1 - 2e-05 24.7 1.5 0.29 11.4 0.0 4.8 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KFP16248.1 - 0.00017 21.1 0.5 0.35 10.3 0.2 3.2 2 2 1 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 KFP16248.1 - 0.0018 17.6 0.2 0.44 9.8 0.1 3.2 2 1 1 3 3 3 1 V-ATPase subunit H DUF3361 PF11841.8 KFP16248.1 - 0.014 15.3 3.6 11 5.9 0.1 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 KFP16248.1 - 0.021 14.9 0.1 0.46 10.5 0.0 2.7 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Moulting_cycle PF04870.16 KFP16248.1 - 0.028 13.7 1.5 0.044 13.1 1.5 1.2 1 0 0 1 1 1 0 Moulting cycle HEAT_PBS PF03130.16 KFP16248.1 - 2.2 9.2 7.9 11 7.1 0.3 5.0 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat V-set PF07686.17 KFP16249.1 - 1e-18 67.5 0.0 2.4e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP16249.1 - 5.4e-14 52.5 1.2 3.2e-06 27.6 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFP16249.1 - 1.3e-12 47.9 0.0 3.9e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.25 KFP16249.1 - 1.7e-09 37.7 0.2 1.5e-05 25.1 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP16249.1 - 3.3e-08 33.5 0.0 0.00027 21.0 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP16249.1 - 1.1e-05 25.7 0.2 0.078 13.3 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP16249.1 - 0.0024 17.9 0.0 0.007 16.4 0.0 1.8 1 0 0 1 1 1 1 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFP16249.1 - 0.064 13.2 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain CVNH PF08881.10 KFP16249.1 - 0.16 12.7 0.0 0.58 10.9 0.0 2.0 2 1 0 2 2 2 0 CVNH domain ASC PF00858.24 KFP16250.1 - 3.1e-108 362.6 12.8 3.8e-108 362.3 12.8 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Synaptobrevin PF00957.21 KFP16251.1 - 5.7e-32 109.4 2.9 6.3e-32 109.2 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin PRIMA1 PF16101.5 KFP16251.1 - 0.0029 17.6 2.2 0.13 12.4 0.4 2.1 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 MCU PF04678.13 KFP16251.1 - 0.0042 17.2 0.3 0.0051 16.9 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Duffy_binding PF05424.11 KFP16251.1 - 0.032 14.3 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Duffy binding domain MRP-L51 PF10244.9 KFP16252.1 - 4.3e-36 123.0 0.6 5e-36 122.8 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit DUF4817 PF16087.5 KFP16252.1 - 0.067 13.0 1.2 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Gp_dh_C PF02800.20 KFP16253.1 - 4.1e-70 234.5 0.0 6.5e-70 233.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFP16253.1 - 1.6e-34 118.2 0.1 4.5e-34 116.8 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.14 KFP16253.1 - 0.027 14.7 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 OstA-like protein Filament PF00038.21 KFP16254.1 - 1.4e-15 57.7 28.0 3.8e-10 39.8 3.6 2.8 3 0 0 3 3 3 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 KFP16254.1 - 0.018 15.0 5.4 0.018 15.0 5.4 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyE PF06109.13 KFP16254.1 - 0.12 11.7 2.0 0.13 11.5 0.0 2.0 3 0 0 3 3 3 0 Haemolysin E (HlyE) T2SSF PF00482.23 KFP16254.1 - 0.17 11.8 0.3 0.4 10.6 0.3 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F PAPA-1 PF04795.12 KFP16254.1 - 0.32 11.8 0.1 0.32 11.8 0.1 3.3 3 1 1 4 4 4 0 PAPA-1-like conserved region Snapin_Pallidin PF14712.6 KFP16254.1 - 0.82 10.1 14.3 0.16 12.4 4.3 3.1 3 1 0 3 3 3 0 Snapin/Pallidin DUF883 PF05957.13 KFP16254.1 - 4.4 8.0 10.9 0.43 11.2 0.5 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SOAR PF16533.5 KFP16254.1 - 9.5 6.3 10.4 0.85 9.6 0.5 2.7 3 0 0 3 3 3 0 STIM1 Orai1-activating region CHDCT2 PF08074.11 KFP16255.1 - 1.4e-87 292.2 0.4 3.4e-87 291.0 0.4 1.7 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1086 PF06461.11 KFP16255.1 - 4.4e-62 208.0 0.0 1.3e-61 206.5 0.0 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.23 KFP16255.1 - 5.2e-41 140.5 1.0 1.7e-40 138.8 0.1 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain DUF1087 PF06465.13 KFP16255.1 - 1.9e-26 91.8 6.0 1.9e-26 91.8 6.0 2.7 3 0 0 3 3 2 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 KFP16255.1 - 9.8e-26 89.5 0.2 2.6e-25 88.1 0.2 1.8 1 0 0 1 1 1 1 CHDNT (NUC034) domain Helicase_C PF00271.31 KFP16255.1 - 2e-22 79.6 0.0 4.4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KFP16255.1 - 2.3e-21 75.4 27.7 1.4e-10 40.9 8.8 2.5 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.24 KFP16255.1 - 1.6e-18 66.3 7.2 2.8e-12 46.3 1.5 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KFP16255.1 - 8.9e-08 32.3 0.0 3.9e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFP16255.1 - 1.3e-05 24.6 0.0 1.3e-05 24.6 0.0 2.1 2 1 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD_2 PF13831.6 KFP16255.1 - 0.0075 15.8 11.6 0.22 11.1 2.7 2.7 2 0 0 2 2 2 2 PHD-finger 7tm_1 PF00001.21 KFP16256.1 - 3.3e-46 157.8 20.1 4.1e-46 157.4 20.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ING PF12998.7 KFP16257.1 - 6.2e-27 94.1 2.0 6.2e-27 94.1 2.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP16257.1 - 2.2e-06 27.5 7.6 4.2e-06 26.6 7.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFP16257.1 - 0.006 16.1 1.1 0.01 15.3 1.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFP16257.1 - 0.008 16.4 0.5 0.019 15.2 0.5 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain Spc7 PF08317.11 KFP16257.1 - 0.013 14.4 7.5 0.016 14.1 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein AP3D1 PF06375.11 KFP16257.1 - 0.014 15.6 5.7 0.017 15.3 5.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1319 PF07028.11 KFP16257.1 - 0.13 12.5 1.0 0.62 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) SOGA PF11365.8 KFP16257.1 - 0.19 12.9 11.2 1.5 10.0 5.5 2.9 1 1 1 2 2 2 0 Protein SOGA ABC_tran_CTD PF16326.5 KFP16257.1 - 0.22 11.8 5.4 0.77 10.0 0.7 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain ORF6C PF10552.9 KFP16257.1 - 0.32 11.1 7.5 1 9.4 2.2 2.1 2 0 0 2 2 2 0 ORF6C domain DASH_Spc19 PF08287.11 KFP16257.1 - 7.6 6.4 15.7 1.5 8.7 8.8 2.0 1 1 0 2 2 2 0 Spc19 AJAP1_PANP_C PF15298.6 KFP16258.1 - 1.5e-07 31.9 0.4 1.9e-06 28.3 0.4 2.0 1 1 0 1 1 1 1 AJAP1/PANP C-terminus EphA2_TM PF14575.6 KFP16258.1 - 0.069 14.0 0.0 0.1 13.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 KFP16258.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CSN7a_helixI PF18392.1 KFP16259.1 - 5.9e-21 74.1 3.3 1.1e-20 73.3 3.3 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 KFP16259.1 - 2.4e-07 31.2 0.4 1.6e-06 28.5 0.2 2.1 2 1 0 2 2 2 1 PCI domain Ribosomal_S3_C PF00189.20 KFP16259.1 - 0.0096 16.4 0.1 0.018 15.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain DUF4200 PF13863.6 KFP16259.1 - 0.011 16.2 2.1 0.025 15.0 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Band_3_cyto PF07565.13 KFP16259.1 - 0.23 11.3 3.5 0.29 10.9 3.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mlf1IP PF10248.9 KFP16260.1 - 8.5e-61 204.9 4.3 1e-60 204.6 4.3 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein V-set PF07686.17 KFP16261.1 - 0.082 13.1 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP16262.1 - 3.9e-09 37.0 0.0 1.1e-05 25.9 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP16262.1 - 8.6e-09 35.5 0.2 0.0001 22.5 0.0 3.0 1 1 2 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP16262.1 - 8.7e-09 35.6 0.4 2e-06 28.0 0.1 2.1 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP16262.1 - 1.6e-07 31.3 0.1 0.017 15.3 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP16262.1 - 2.2e-07 30.8 0.0 0.00051 20.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP16262.1 - 0.0062 16.1 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP16262.1 - 0.019 15.0 0.0 1.1 9.4 0.0 2.5 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain V-set PF07686.17 KFP16263.1 - 6.2e-13 48.9 2.6 0.00033 20.8 0.1 4.2 3 2 1 4 4 4 3 Immunoglobulin V-set domain Tcell_CD4_C PF12104.8 KFP16263.1 - 3.6e-11 42.8 14.3 5.2e-11 42.2 12.2 2.2 2 0 0 2 2 2 1 T cell CD4 receptor C terminal region ig PF00047.25 KFP16263.1 - 1.9e-10 40.8 3.8 0.11 12.7 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.6 KFP16263.1 - 1.5e-09 38.3 0.6 0.74 10.5 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP16263.1 - 1.6e-09 38.0 2.2 0.8 10.1 0.1 4.3 3 1 1 4 4 4 4 Immunoglobulin domain CD4-extracel PF09191.10 KFP16263.1 - 6.5e-08 33.0 0.4 1.6e-07 31.7 0.4 1.7 1 0 0 1 1 1 1 CD4, extracellular Izumo-Ig PF16706.5 KFP16263.1 - 7e-06 26.0 0.0 2.8 8.1 0.0 4.2 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain I-set PF07679.16 KFP16263.1 - 1.6e-05 24.9 0.8 3.5 7.8 0.1 4.4 3 1 2 5 5 5 3 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP16263.1 - 2.3e-05 23.8 0.0 0.92 9.1 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set PF05790.15 KFP16263.1 - 0.00027 21.1 5.1 0.14 12.3 0.4 4.5 4 1 0 4 4 4 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFP16263.1 - 0.0004 20.4 0.9 0.21 11.5 0.5 3.3 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain PMP1_2 PF08114.11 KFP16263.1 - 0.057 13.2 1.9 0.11 12.3 1.9 1.4 1 0 0 1 1 1 0 ATPase proteolipid family DUF3318 PF11780.8 KFP16263.1 - 0.089 12.7 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) 7tm_1 PF00001.21 KFP16264.1 - 0.0038 16.6 2.4 0.0067 15.8 2.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TIM PF00121.18 KFP16265.1 - 5.7e-80 268.2 0.1 6.4e-80 268.0 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LRR_4 PF12799.7 KFP16266.1 - 4.6e-23 80.9 25.2 8.4e-09 35.6 0.7 5.6 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP16266.1 - 5.6e-19 68.3 7.5 1.3e-16 60.6 2.2 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFP16266.1 - 3.4e-14 52.3 30.0 1.2e-05 25.0 3.1 5.4 2 1 5 7 7 7 6 Leucine rich repeat LRR_6 PF13516.6 KFP16266.1 - 2.9e-06 26.9 22.7 0.18 11.9 0.1 8.5 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 KFP16266.1 - 0.00026 21.1 12.7 6.6 7.7 1.1 6.8 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_3 PF07725.12 KFP16266.1 - 0.23 11.3 3.6 8.1 6.5 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Enolase_C PF00113.22 KFP16267.1 - 4e-158 525.3 0.0 5e-158 525.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFP16267.1 - 1.1e-59 200.3 0.0 2e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFP16267.1 - 2.8e-09 36.9 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFP16267.1 - 3.5e-05 23.1 0.3 7.7e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Y_phosphatase PF00102.27 KFP16268.1 - 9.9e-78 260.9 0.1 1.6e-77 260.2 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 KFP16268.1 - 1.2e-46 156.7 0.4 5.3e-22 77.7 0.0 3.0 3 0 0 3 3 3 2 SH2 domain DSPc PF00782.20 KFP16268.1 - 1.6e-05 24.7 0.1 6.9e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP16268.1 - 0.00092 19.2 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP16268.1 - 0.047 13.8 1.6 0.083 13.0 0.0 2.3 3 1 1 4 4 4 0 Inositol hexakisphosphate MRNIP PF15749.5 KFP16268.1 - 0.13 13.0 0.3 0.13 13.0 0.3 2.3 2 0 0 2 2 2 0 MRN-interacting protein EMG1 PF03587.14 KFP16269.1 - 3.7e-67 225.8 0.0 4.1e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MBOAT PF03062.19 KFP16270.1 - 3e-65 220.9 13.4 3e-65 220.9 13.4 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CUB PF00431.20 KFP16271.1 - 2.2e-51 172.8 0.1 5.5e-28 97.5 0.1 2.4 2 0 0 2 2 2 2 CUB domain Trypsin PF00089.26 KFP16271.1 - 5.5e-50 170.2 0.0 8.1e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sushi PF00084.20 KFP16271.1 - 2.8e-15 56.7 19.2 1.6e-10 41.4 0.3 4.3 3 1 1 4 4 4 2 Sushi repeat (SCR repeat) FXa_inhibition PF14670.6 KFP16271.1 - 2.7e-10 40.3 12.1 1.7e-09 37.8 9.3 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP16271.1 - 2.8e-05 23.9 8.0 0.0005 19.9 5.1 3.3 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP16271.1 - 0.00026 21.1 10.9 0.0005 20.2 9.2 2.5 2 0 0 2 2 2 1 Calcium-binding EGF domain CUB_2 PF02408.20 KFP16271.1 - 0.00037 20.2 0.2 0.44 10.3 0.0 2.9 3 0 0 3 3 3 2 CUB-like domain EGF PF00008.27 KFP16271.1 - 0.0041 17.4 7.8 0.024 14.9 7.8 2.5 1 0 0 1 1 1 1 EGF-like domain Plasmod_Pvs28 PF06247.11 KFP16271.1 - 0.23 11.8 2.3 11 6.4 0.0 2.9 2 0 0 2 2 2 0 Pvs28 EGF domain hEGF PF12661.7 KFP16271.1 - 0.3 11.8 7.6 2.1 9.1 7.6 2.7 1 0 0 1 1 1 0 Human growth factor-like EGF DUF4215 PF13948.6 KFP16271.1 - 0.78 10.2 9.3 2 8.9 0.8 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) HRM PF02793.22 KFP16271.1 - 0.87 9.9 4.9 20 5.6 0.2 3.7 3 0 0 3 3 3 0 Hormone receptor domain Lipocalin_7 PF14651.6 KFP16272.1 - 0.0083 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Cadherin PF00028.17 KFP16273.1 - 8.1e-13 48.6 0.0 1.3e-06 28.7 0.0 2.8 3 0 0 3 3 3 2 Cadherin domain Laminin_G_3 PF13385.6 KFP16273.1 - 2.7e-06 27.6 0.0 8.7e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KFP16273.1 - 0.017 15.7 0.0 0.049 14.2 0.0 1.8 1 0 0 1 1 1 0 Laminin G domain Mito_carr PF00153.27 KFP16274.1 - 2.9e-62 206.6 0.1 3.4e-21 74.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 7tm_4 PF13853.6 KFP16275.1 - 7.1e-39 134.2 20.8 8.6e-39 133.9 20.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16275.1 - 1.7e-21 76.7 19.4 2.4e-21 76.2 19.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gaa1 PF04114.14 KFP16275.1 - 0.061 12.3 14.4 0.1 11.6 14.2 1.4 1 1 0 1 1 1 0 Gaa1-like, GPI transamidase component Pkinase_Tyr PF07714.17 KFP16276.1 - 6.3e-97 323.9 0.0 9.3e-97 323.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP16276.1 - 2.9e-51 174.0 1.0 4.6e-51 173.4 1.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP16276.1 - 1e-47 162.7 0.0 1.5e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP16276.1 - 1.7e-23 82.8 0.0 7.9e-11 42.2 0.0 2.7 3 0 0 3 3 2 2 Fibronectin type III domain SAM_1 PF00536.30 KFP16276.1 - 4.6e-21 75.0 0.0 1.1e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP16276.1 - 1.1e-17 63.8 0.0 2.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFP16276.1 - 1.3e-14 54.8 0.0 2.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Pur_ac_phosph_N PF16656.5 KFP16276.1 - 1.2e-07 32.2 0.0 6.5e-05 23.4 0.0 2.7 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Ephrin_rec_like PF07699.13 KFP16276.1 - 2.4e-07 30.4 3.5 2.4e-07 30.4 3.5 3.2 2 1 1 3 3 3 1 Putative ephrin-receptor like Tissue_fac PF01108.17 KFP16276.1 - 0.014 15.3 0.0 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 Tissue factor Haspin_kinase PF12330.8 KFP16276.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Tudor_4 PF18358.1 KFP16276.1 - 0.083 12.5 0.1 19 4.9 0.0 2.7 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Kdo PF06293.14 KFP16276.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-B_box PF00643.24 KFP16276.1 - 0.11 12.7 1.1 0.36 11.0 1.1 1.8 1 0 0 1 1 1 0 B-box zinc finger PMP1_2 PF08114.11 KFP16276.1 - 0.17 11.7 3.4 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 ATPase proteolipid family LIM PF00412.22 KFP16277.1 - 4.6e-34 116.4 33.8 5.8e-13 48.9 8.6 3.2 3 0 0 3 3 3 3 LIM domain zf_C2H2_13 PF18508.1 KFP16277.1 - 0.028 14.0 1.6 0.07 12.7 0.2 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-dskA_traR PF01258.17 KFP16277.1 - 0.098 12.6 0.2 0.098 12.6 0.2 5.1 4 2 1 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger DUF2321 PF10083.9 KFP16277.1 - 3.7 7.2 14.6 6.9 6.3 5.9 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) FAM131 PF15010.6 KFP16278.1 - 2.4e-100 336.3 5.3 4.7e-100 335.3 5.3 1.4 1 1 0 1 1 1 1 Putative cell signalling Peptidase_C14 PF00656.22 KFP16279.1 - 9.5e-43 146.9 0.2 2.5e-42 145.5 0.1 1.7 2 0 0 2 2 2 1 Caspase domain CARD PF00619.21 KFP16279.1 - 8.9e-20 70.5 0.7 1.9e-19 69.4 0.7 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KFP16279.1 - 2.2e-06 27.6 0.8 4.2e-06 26.7 0.8 1.5 1 0 0 1 1 1 1 Caspase recruitment domain TMEM51 PF15345.6 KFP16280.1 - 0.043 13.6 0.5 0.052 13.4 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Rap_GAP PF02145.15 KFP16281.1 - 1.6e-64 216.9 0.0 2.5e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.17 KFP16281.1 - 0.00016 21.1 1.6 0.00034 20.1 1.6 1.6 1 0 0 1 1 1 1 GoLoco motif DSBA PF01323.20 KFP16282.1 - 4.6e-38 130.9 0.0 5.5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Ank_2 PF12796.7 KFP16283.1 - 8.9e-27 93.5 7.1 3.5e-12 46.7 1.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ion_trans PF00520.31 KFP16283.1 - 4.6e-20 71.9 22.1 7.3e-20 71.2 22.1 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 KFP16283.1 - 9.7e-19 65.5 2.5 0.0001 22.4 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFP16283.1 - 2.1e-15 56.9 0.8 0.00011 22.7 0.0 4.8 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP16283.1 - 2.3e-15 56.4 3.0 0.027 14.8 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP16283.1 - 3.1e-13 49.5 1.2 0.0084 16.5 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat OKR_DC_1 PF01276.20 KFP16283.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase_Tyr PF07714.17 KFP16284.1 - 9.6e-96 320.0 0.0 1.3e-95 319.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP16284.1 - 2.2e-71 239.6 0.1 3.8e-71 238.8 0.1 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP16284.1 - 3.1e-46 157.9 0.0 4.5e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP16284.1 - 7.5e-27 93.5 0.1 8e-16 58.2 0.1 3.1 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.17 KFP16284.1 - 4.3e-20 71.6 0.1 8e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP16284.1 - 7.9e-19 67.9 0.1 1.9e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFP16284.1 - 2.4e-18 66.8 0.0 4.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KFP16284.1 - 7.3e-07 28.9 1.2 7.3e-07 28.9 1.2 2.4 2 0 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFP16284.1 - 8.8e-05 23.0 0.1 0.00044 20.8 0.1 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain cEGF PF12662.7 KFP16284.1 - 0.0093 15.9 1.1 0.033 14.1 1.1 1.9 1 0 0 1 1 1 1 Complement Clr-like EGF-like Y_Y_Y PF07495.13 KFP16284.1 - 0.013 15.4 0.1 0.044 13.7 0.1 1.9 2 0 0 2 2 2 0 Y_Y_Y domain Kdo PF06293.14 KFP16284.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP16284.1 - 0.039 12.9 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Interfer-bind PF09294.10 KFP16284.1 - 0.056 13.8 0.0 0.68 10.3 0.0 2.5 3 0 0 3 3 2 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_fungal PF17667.1 KFP16284.1 - 0.092 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EGF_CA PF07645.15 KFP16284.1 - 9.1 6.6 7.0 10 6.4 0.5 2.6 2 0 0 2 2 2 0 Calcium-binding EGF domain C1-set PF07654.15 KFP16285.1 - 1.8e-18 66.6 0.0 2.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFP16285.1 - 0.0004 20.9 0.0 0.00048 20.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP16285.1 - 0.056 13.6 0.2 0.072 13.3 0.2 1.2 1 0 0 1 1 1 0 Immunoglobulin domain PDZ PF00595.24 KFP16286.1 - 4e-93 305.9 2.1 8.4e-13 48.5 0.1 7.2 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 KFP16286.1 - 4.5e-70 231.4 8.9 2e-12 46.7 0.1 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 KFP16286.1 - 5.5e-38 129.2 0.9 1.8e-05 25.0 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.6 KFP16286.1 - 5.4e-10 39.1 2.5 0.23 11.5 0.0 6.6 6 0 0 6 6 6 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KFP16286.1 - 7.9e-05 23.0 0.0 4.8 7.5 0.0 4.7 4 2 2 6 6 6 2 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 KFP16286.1 - 0.011 16.1 1.0 12 6.3 0.0 4.6 6 0 0 6 6 6 0 PDZ domain EutA PF06277.11 KFP16286.1 - 0.016 14.1 0.3 0.11 11.3 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA MoaE PF02391.17 KFP16286.1 - 0.19 12.0 0.1 21 5.4 0.0 3.0 3 0 0 3 3 3 0 MoaE protein SNF PF00209.18 KFP16287.1 - 1e-235 783.4 37.5 1.2e-235 783.2 37.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LSM PF01423.22 KFP16288.1 - 2.4e-20 72.0 0.2 3.1e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.18 KFP16288.1 - 0.045 13.1 0.1 0.063 12.7 0.1 1.4 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF150_C PF17384.2 KFP16288.1 - 0.064 13.4 0.2 0.11 12.7 0.2 1.5 1 1 0 1 1 1 0 RimP C-terminal SH3 domain Glutaredoxin PF00462.24 KFP16288.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin BHD_3 PF10405.9 KFP16289.1 - 6.7e-27 93.7 0.0 1.5e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KFP16289.1 - 2e-22 79.5 0.6 2e-22 79.5 0.6 3.9 5 0 0 5 5 5 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KFP16289.1 - 1.4e-16 60.0 0.0 3.3e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFP16289.1 - 8.4e-15 55.5 0.4 8.4e-15 55.5 0.4 5.1 5 1 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KFP16289.1 - 0.06 13.8 0.0 0.92 10.0 0.0 2.6 2 0 0 2 2 2 0 Transglutaminase-like superfamily TMEM43 PF07787.12 KFP16290.1 - 8.8e-88 293.9 0.0 1.3e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 43 Urocanase_C PF17392.2 KFP16292.1 - 2.2e-88 294.8 1.6 3.3e-88 294.3 1.6 1.2 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 KFP16292.1 - 7.2e-82 274.1 0.1 6e-44 150.2 0.0 2.5 2 0 0 2 2 2 2 Urocanase Rossmann-like domain Urocanase_N PF17391.2 KFP16292.1 - 4.8e-46 155.6 0.2 5.3e-45 152.2 0.2 2.5 1 1 0 1 1 1 1 Urocanase N-terminal domain GntP_permease PF02447.16 KFP16292.1 - 0.031 13.0 0.1 0.064 11.9 0.1 1.4 1 0 0 1 1 1 0 GntP family permease zf-C2H2 PF00096.26 KFP16293.1 - 1.4e-13 50.5 38.5 0.00061 20.1 0.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP16293.1 - 1.7e-11 44.0 38.1 0.01 16.6 0.6 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP16293.1 - 9e-07 29.0 31.6 0.011 16.1 0.1 5.7 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KFP16293.1 - 5.6e-05 23.3 18.1 0.62 10.2 0.5 4.8 1 1 2 4 4 4 3 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFP16293.1 - 0.0002 21.6 15.3 0.024 14.9 1.8 4.0 1 1 3 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KFP16293.1 - 0.62 10.1 23.1 2.1 8.5 1.9 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFP16293.1 - 0.68 10.6 17.0 3.2 8.4 0.6 4.9 3 3 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KFP16294.1 - 6.5e-15 54.7 20.5 3.2e-05 24.1 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP16294.1 - 5.1e-13 48.8 20.0 4e-09 36.5 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP16294.1 - 1.1e-07 32.0 28.3 0.00037 21.1 2.1 4.1 5 0 0 5 5 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP16294.1 - 2.1e-05 25.1 8.2 0.19 12.4 0.2 3.7 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 KFP16294.1 - 0.011 15.6 0.9 0.068 13.0 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KFP16294.1 - 0.011 16.1 4.4 0.18 12.3 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2225 PF09986.9 KFP16294.1 - 0.043 13.5 0.4 0.13 12.0 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3512 PF12024.8 KFP16294.1 - 0.15 11.5 1.5 0.3 10.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) IBR PF01485.21 KFP16294.1 - 0.47 10.7 5.1 4.4 7.6 5.1 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 KFP16294.1 - 0.72 10.2 6.8 0.3 11.4 2.0 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFP16294.1 - 1.5 8.8 4.4 0.51 10.3 0.5 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KFP16294.1 - 3.2 8.1 6.3 2.1 8.8 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP16294.1 - 5.2 7.4 12.0 0.19 12.1 4.8 2.3 3 1 0 3 3 3 0 C2H2-type zinc ribbon MgtE PF01769.16 KFP16295.1 - 2.5e-34 118.3 25.5 8e-23 81.2 7.7 3.3 4 0 0 4 4 4 2 Divalent cation transporter GNVR PF13807.6 KFP16295.1 - 1.6 8.7 3.9 0.45 10.5 0.4 1.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Sulfotransfer_2 PF03567.14 KFP16296.1 - 8e-70 235.6 4.1 9.6e-70 235.4 4.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4543 PF15076.6 KFP16296.1 - 0.073 13.2 0.7 0.15 12.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Pyr_redox_2 PF07992.14 KFP16298.1 - 1e-52 179.3 0.1 1.2e-52 179.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP16298.1 - 9.5e-29 99.9 0.0 3.1e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP16298.1 - 5.1e-16 59.0 3.6 2.5e-13 50.4 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP16298.1 - 2.6e-14 53.2 0.7 4.4e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP16298.1 - 7.7e-07 28.5 0.0 3.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFP16298.1 - 0.0013 18.1 0.3 0.77 9.0 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFP16298.1 - 0.0013 17.5 0.3 0.0029 16.4 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFP16298.1 - 0.004 16.4 0.7 0.015 14.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KFP16298.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KFP16298.1 - 0.072 12.7 2.0 0.11 12.1 0.4 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KFP16298.1 - 0.081 12.0 2.5 0.37 9.8 2.5 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFP16298.1 - 0.47 10.7 7.0 0.25 11.6 0.7 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Plexin_cytopl PF08337.12 KFP16299.1 - 3.4e-262 871.1 5.7 4.1e-262 870.8 5.7 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 KFP16299.1 - 1.2e-43 147.0 12.1 5e-13 48.9 0.1 5.7 4 1 1 5 5 5 4 IPT/TIG domain TIG_2 PF18020.1 KFP16299.1 - 6.2e-32 110.1 0.1 2.3e-31 108.3 0.1 2.1 1 0 0 1 1 1 1 TIG domain found in plexin TIG_plexin PF17960.1 KFP16299.1 - 3.2e-27 94.4 6.1 2.8e-22 78.5 0.0 5.5 7 0 0 7 7 7 2 TIG domain PSI PF01437.25 KFP16299.1 - 4.9e-21 75.0 53.0 3.2e-09 37.2 12.7 3.8 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.19 KFP16299.1 - 0.0012 18.6 1.2 0.0084 15.8 1.2 2.1 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PSI_integrin PF17205.3 KFP16299.1 - 0.33 10.7 48.2 0.012 15.3 11.3 3.9 3 0 0 3 3 3 0 Integrin plexin domain Sema PF01403.19 KFP16300.1 - 5e-68 229.9 0.0 5.7e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Sema domain MCM PF00493.23 KFP16303.1 - 1.2e-98 328.7 0.0 1.9e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP16303.1 - 8.2e-37 125.9 0.1 1.6e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFP16303.1 - 3.9e-29 100.9 1.7 9.6e-29 99.7 1.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFP16303.1 - 6.3e-17 62.1 1.5 1.3e-16 61.1 0.3 2.2 2 0 0 2 2 1 1 MCM N-terminal domain MCM2_N PF12619.8 KFP16303.1 - 1.8e-15 57.5 19.3 1.8e-15 57.5 19.3 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KFP16303.1 - 1.3e-08 34.5 0.0 5.3e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFP16303.1 - 4.1e-07 29.9 0.0 3.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP16303.1 - 6e-07 29.5 0.0 2.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KFP16303.1 - 0.0011 18.8 0.4 0.004 17.0 0.1 2.2 2 0 0 2 2 1 1 AAA lid domain Sigma54_activat PF00158.26 KFP16303.1 - 0.0028 17.4 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 KFP16303.1 - 0.0032 17.9 0.0 0.009 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFP16303.1 - 0.01 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 KFP16303.1 - 0.047 13.8 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain BTB PF00651.31 KFP16304.1 - 5e-43 145.8 2.6 6.2e-21 74.7 0.1 3.4 2 1 1 3 3 3 3 BTB/POZ domain Ank_5 PF13857.6 KFP16304.1 - 2e-07 31.2 0.1 6.4e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP16304.1 - 2.4e-07 31.3 0.0 1.8e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP16304.1 - 1.7e-06 28.5 0.2 1.2e-05 25.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3342 PF11822.8 KFP16304.1 - 2.1e-05 24.6 0.9 0.076 13.2 0.1 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3342) Ank_3 PF13606.6 KFP16304.1 - 5.1e-05 23.4 0.4 0.00084 19.6 0.0 3.2 4 0 0 4 4 3 1 Ankyrin repeat BACK PF07707.15 KFP16304.1 - 0.00073 19.6 0.4 0.003 17.6 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ank PF00023.30 KFP16304.1 - 0.0013 19.1 0.0 0.0041 17.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat P4Ha_N PF08336.11 KFP16304.1 - 0.03 14.3 1.6 0.091 12.8 0.3 2.3 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Orn_Arg_deC_N PF02784.16 KFP16304.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain IFT20 PF14931.6 KFP16304.1 - 0.4 10.9 4.8 0.34 11.1 2.7 2.0 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Hydrolase_4 PF12146.8 KFP16305.1 - 1.5e-60 204.4 0.2 2.5e-57 193.9 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP16305.1 - 1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP16305.1 - 2.3e-07 31.7 0.2 2.9e-07 31.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KFP16305.1 - 1.8e-05 24.6 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 KFP16305.1 - 3.4e-05 23.7 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KFP16305.1 - 0.00015 21.9 0.1 0.00047 20.4 0.1 1.7 2 1 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KFP16305.1 - 0.00051 19.8 0.1 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF2436 PF10365.9 KFP16305.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Abhydrolase_5 PF12695.7 KFP16305.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KFP16305.1 - 0.085 12.4 0.0 6.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFP16305.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1350 PF07082.11 KFP16305.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) LIDHydrolase PF10230.9 KFP16305.1 - 0.12 11.9 0.1 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Kelch_1 PF01344.25 KFP16307.1 - 3e-31 106.7 11.1 5.3e-10 38.7 0.0 5.2 5 1 0 5 5 5 4 Kelch motif BACK PF07707.15 KFP16307.1 - 1.1e-28 99.4 1.5 1.1e-28 99.4 1.5 2.6 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 KFP16307.1 - 1.9e-23 82.8 4.3 2.5e-23 82.4 2.6 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 KFP16307.1 - 3.1e-22 78.1 3.6 2e-08 34.2 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KFP16307.1 - 9e-16 57.2 3.6 1e-07 31.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KFP16307.1 - 1.1e-10 41.4 5.3 0.003 17.5 0.0 5.1 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP16307.1 - 1.1e-10 41.5 1.8 0.0065 16.7 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP16307.1 - 1.5e-10 40.8 0.1 7.8e-05 22.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif DUF3342 PF11822.8 KFP16307.1 - 2.6e-05 24.3 0.9 0.00031 20.9 0.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3342) SecY PF00344.20 KFP16308.1 - 7.1e-77 258.7 12.0 9.5e-77 258.3 12.0 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFP16308.1 - 8.2e-19 67.2 0.2 2.4e-18 65.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p YlaH PF14036.6 KFP16308.1 - 0.11 12.8 3.3 1.9 8.8 0.2 3.2 3 0 0 3 3 3 0 YlaH-like protein DUF2975 PF11188.8 KFP16308.1 - 0.25 11.2 9.1 0.065 13.1 0.7 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) TIP49 PF06068.13 KFP16309.1 - 2.2e-156 520.5 0.3 2.7e-156 520.2 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFP16309.1 - 2.1e-27 95.0 0.1 5.8e-27 93.6 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFP16309.1 - 3.6e-13 50.1 0.3 2.4e-08 34.5 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP16309.1 - 5.5e-09 36.0 0.2 1.6e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP16309.1 - 2.3e-06 27.9 0.1 0.1 12.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFP16309.1 - 4e-05 24.1 0.0 0.00037 20.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFP16309.1 - 4e-05 23.6 0.1 0.0036 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFP16309.1 - 0.00013 21.6 0.0 0.00077 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFP16309.1 - 0.00028 20.6 0.1 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 KFP16309.1 - 0.00077 19.8 1.6 0.022 15.1 1.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP16309.1 - 0.0011 19.5 0.0 0.0092 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFP16309.1 - 0.0013 18.2 0.1 0.081 12.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFP16309.1 - 0.0021 17.9 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KFP16309.1 - 0.0021 18.3 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KFP16309.1 - 0.0026 17.2 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KFP16309.1 - 0.0092 15.3 0.2 0.028 13.7 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KFP16309.1 - 0.0096 16.1 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KFP16309.1 - 0.01 15.3 0.1 0.033 13.6 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 KFP16309.1 - 0.011 15.8 0.1 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KFP16309.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFP16309.1 - 0.014 14.9 0.1 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFP16309.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFP16309.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KFP16309.1 - 0.028 13.7 1.0 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 KFP16309.1 - 0.031 14.0 0.2 0.71 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFP16309.1 - 0.042 13.9 0.0 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KFP16309.1 - 0.059 12.5 0.1 0.13 11.4 0.1 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KFP16309.1 - 0.063 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta2 PF13177.6 KFP16309.1 - 0.071 12.9 0.0 1.9 8.2 0.0 2.2 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_lid_4 PF17864.1 KFP16309.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain RNA_helicase PF00910.22 KFP16309.1 - 0.085 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 KFP16310.1 - 8.5e-08 32.0 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFP16310.1 - 9.3e-08 32.4 0.1 2.4e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 KFP16310.1 - 0.00018 21.2 1.0 0.00028 20.5 1.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FliS_cochap PF16522.5 KFP16310.1 - 0.0086 16.0 0.9 0.041 13.8 0.3 2.3 3 0 0 3 3 3 1 Flagellar FLiS export co-chaperone, HP1076 Gtr1_RagA PF04670.12 KFP16310.1 - 0.1 11.9 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFP16310.1 - 0.22 11.4 1.9 0.36 10.7 0.1 2.1 3 0 0 3 3 3 0 RsgA GTPase Ribophorin_I PF04597.14 KFP16311.1 - 6.6e-137 457.3 8.0 8.3e-137 457.0 8.0 1.1 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.6 KFP16311.1 - 0.0013 19.4 0.9 0.0027 18.3 0.4 1.8 2 0 0 2 2 2 1 DNA repair REX1-B Ras PF00071.22 KFP16312.1 - 1.6e-58 196.9 0.1 1.9e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16312.1 - 2.3e-32 111.7 0.0 3.8e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16312.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP16312.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP16312.1 - 2.6e-06 27.5 0.2 0.0033 17.3 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KFP16312.1 - 3.5e-06 26.5 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP16312.1 - 1.2e-05 25.0 0.0 0.00077 19.0 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KFP16312.1 - 0.0026 17.4 0.0 0.0096 15.5 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KFP16312.1 - 0.0028 17.0 0.6 0.021 14.1 0.1 2.1 2 1 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 KFP16312.1 - 0.0031 17.3 0.3 0.084 12.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFP16312.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KFP16312.1 - 0.0053 16.5 0.0 0.12 12.1 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP16312.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFP16312.1 - 0.015 15.0 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KFP16312.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KFP16312.1 - 0.019 15.3 0.1 0.035 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KFP16312.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KFP16312.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFP16312.1 - 0.041 13.1 1.2 0.3 10.2 0.2 2.2 2 1 1 3 3 3 0 G-protein alpha subunit TniB PF05621.11 KFP16312.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KFP16312.1 - 0.07 13.0 0.7 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFP16312.1 - 0.087 12.0 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KFP16312.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFP16312.1 - 0.18 12.4 0.1 0.5 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter SRAP PF02586.14 KFP16313.1 - 9.8e-59 198.5 0.0 1.7e-58 197.8 0.0 1.4 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) Adaptin_N PF01602.20 KFP16314.1 - 6.2e-136 454.0 10.3 7.7e-136 453.7 10.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFP16314.1 - 4.1e-59 199.0 0.4 9.5e-59 197.9 0.4 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFP16314.1 - 9.4e-38 128.9 0.0 2.1e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFP16314.1 - 5.4e-18 65.2 0.1 3.9e-08 33.6 0.0 6.2 3 2 3 7 7 7 3 HEAT repeats Cnd1 PF12717.7 KFP16314.1 - 2.4e-13 50.4 10.8 0.0013 18.8 0.1 5.5 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP16314.1 - 1.2e-05 25.2 4.3 9 6.9 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KFP16314.1 - 7.8e-05 23.1 1.2 0.51 10.9 0.1 3.7 3 0 0 3 3 3 2 HEAT-like repeat MOR2-PAG1_C PF14225.6 KFP16314.1 - 0.053 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HEAT_PBS PF03130.16 KFP16314.1 - 0.077 13.7 1.3 29 5.7 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 KFP16314.1 - 0.087 12.9 0.1 6.8 6.9 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 KFP16314.1 - 0.28 11.1 2.5 0.45 10.5 0.2 2.6 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Peptidase_M16 PF00675.20 KFP16315.1 - 9.6e-50 168.4 0.0 1.5e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP16315.1 - 3.8e-37 128.1 0.0 3.3e-36 125.0 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain SAP30_Sin3_bdg PF13867.6 KFP16315.1 - 0.079 13.3 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Virulence_RhuM PF13310.6 KFP16315.1 - 0.1 11.8 0.0 6.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Virulence protein RhuM family IPK PF03770.16 KFP16316.1 - 6.1e-65 218.8 0.5 1.3e-64 217.7 0.5 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase SpoU_sub_bind PF08032.12 KFP16316.1 - 0.11 12.8 0.7 0.31 11.4 0.7 1.9 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Abhydrolase_1 PF00561.20 KFP16317.1 - 6.3e-25 88.3 0.0 4.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP16317.1 - 1e-19 72.1 0.0 2e-19 71.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP16317.1 - 1.6e-14 53.8 0.0 5.7e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFP16317.1 - 6e-06 25.2 0.0 4e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.12 KFP16317.1 - 0.00063 18.9 0.0 0.00084 18.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) UPF0227 PF05728.12 KFP16317.1 - 0.0016 18.4 0.4 1.1 9.1 0.0 2.4 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KFP16317.1 - 0.0093 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 KFP16317.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase FSH1 PF03959.13 KFP16317.1 - 0.07 12.8 0.2 4.4 6.9 0.0 2.5 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Exo_endo_phos PF03372.23 KFP16318.1 - 6.9e-13 48.7 0.0 8.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Filamin PF00630.19 KFP16319.1 - 0 1257.9 51.6 5e-20 72.2 0.0 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat CH PF00307.31 KFP16319.1 - 9.9e-18 64.3 0.0 1.8e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 KFP16319.1 - 3.8e-16 58.8 27.3 0.42 10.6 0.0 14.6 17 0 0 17 17 16 5 Y_Y_Y domain Big_3_5 PF16640.5 KFP16319.1 - 1.4e-15 57.3 32.5 0.16 12.2 0.0 14.1 15 0 0 15 15 15 5 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 KFP16319.1 - 7.4e-13 48.6 25.1 0.018 15.3 0.0 11.1 13 1 0 13 13 12 5 Invasin, domain 3 DUF5060 PF16586.5 KFP16319.1 - 1.1e-12 48.2 1.9 2.5 8.6 0.0 12.2 15 0 0 15 15 15 3 Domain of unknown function (DUF5060) YtkA PF13115.6 KFP16319.1 - 2.2e-10 41.0 13.1 1.9 9.1 0.1 12.6 15 0 0 15 15 14 3 YtkA-like BatD PF13584.6 KFP16319.1 - 2.8e-05 23.1 1.6 0.12 11.2 0.0 4.0 5 0 0 5 5 5 2 Oxygen tolerance DUF2141 PF09912.9 KFP16319.1 - 8.3e-05 22.5 1.0 47 3.9 0.0 6.9 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2141) PapC_N PF13954.6 KFP16319.1 - 0.0079 16.2 0.0 5.4 7.0 0.0 5.3 6 0 0 6 6 6 1 PapC N-terminal domain Big_1 PF02369.16 KFP16319.1 - 0.0086 16.1 9.2 60 3.7 0.1 8.1 8 0 0 8 8 8 0 Bacterial Ig-like domain (group 1) DUF3568 PF12092.8 KFP16319.1 - 0.11 12.6 0.0 7.5 6.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3568) PEGA PF08308.11 KFP16319.1 - 0.17 11.8 4.6 1.1e+02 2.8 0.1 7.1 7 0 0 7 7 7 0 PEGA domain FHA PF00498.26 KFP16320.1 - 7.8e-18 64.6 0.1 2.9e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 FHA domain GAS PF13851.6 KFP16320.1 - 0.0012 18.2 121.0 0.026 13.9 11.1 6.7 3 2 3 6 6 6 4 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KFP16320.1 - 0.0068 16.6 12.0 0.0068 16.6 12.0 6.0 2 2 3 6 6 6 4 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KFP16320.1 - 0.0095 15.7 5.8 0.0095 15.7 5.8 6.7 3 3 3 6 6 6 2 Hepatic lectin, N-terminal domain T3SSipB PF16535.5 KFP16320.1 - 0.012 16.1 7.8 0.012 16.1 7.8 5.6 2 2 2 5 5 5 0 Type III cell invasion protein SipB APG6_N PF17675.1 KFP16320.1 - 0.018 15.6 18.2 0.018 15.6 18.2 8.0 2 2 5 7 7 7 0 Apg6 coiled-coil region SPA PF08616.10 KFP16322.1 - 3.8e-16 59.0 0.2 4.9e-15 55.5 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 KFP16322.1 - 8.1e-06 25.9 3.9 8.1e-06 25.9 3.9 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 KFP16322.1 - 0.0044 15.8 0.0 0.0085 14.8 0.0 1.5 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.6 KFP16322.1 - 0.17 12.5 0.1 0.41 11.3 0.1 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Arf PF00025.21 KFP16323.1 - 6.5e-73 243.9 0.2 7e-73 243.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP16323.1 - 1.5e-14 53.8 0.0 1.8e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFP16323.1 - 2.4e-14 53.3 0.0 2.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16323.1 - 3.1e-14 53.2 0.0 4.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFP16323.1 - 2.6e-11 43.3 0.9 1.6e-09 37.4 0.2 2.4 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KFP16323.1 - 1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP16323.1 - 1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFP16323.1 - 0.017 14.4 0.1 0.026 13.8 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 KFP16323.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 LepB_N PF18640.1 KFP16323.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 LepB N-terminal domain AAA_18 PF13238.6 KFP16323.1 - 0.16 12.5 0.1 0.33 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.23 KFP16324.1 - 2.3e-22 79.6 0.0 4.5e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_6 PF12774.7 KFP16326.1 - 7.1e-158 524.8 0.1 4.2e-155 515.7 0.0 3.1 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP16326.1 - 1e-141 472.6 18.3 1e-141 472.6 18.3 3.0 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KFP16326.1 - 1.6e-118 395.5 0.0 5.6e-118 393.6 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KFP16326.1 - 5.9e-103 343.7 1.0 1.8e-102 342.1 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KFP16326.1 - 9.5e-91 302.8 1.0 9.5e-91 302.8 1.0 3.1 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KFP16326.1 - 5.1e-84 280.3 0.1 1.7e-81 272.1 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KFP16326.1 - 4.4e-62 208.7 0.0 1.5e-61 207.0 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KFP16326.1 - 1.9e-49 168.6 10.7 1.9e-49 168.6 10.7 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KFP16326.1 - 5.4e-48 162.0 0.6 1.1e-46 157.7 0.0 3.5 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KFP16326.1 - 3.9e-30 104.6 0.1 2.3e-29 102.1 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFP16326.1 - 5.4e-18 65.3 0.0 1.1e-05 25.5 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KFP16326.1 - 3.2e-17 62.6 1.7 1.2e-16 60.7 1.7 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KFP16326.1 - 1.9e-06 28.3 6.5 0.023 15.1 0.0 5.3 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP16326.1 - 4.9e-05 23.8 0.0 0.47 10.8 0.0 4.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KFP16326.1 - 5.2e-05 23.5 0.2 1.3 9.3 0.0 5.2 4 1 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KFP16326.1 - 0.00035 20.9 0.6 6.1 7.3 0.0 4.7 5 0 0 5 5 4 1 RNA helicase AAA_24 PF13479.6 KFP16326.1 - 0.01 15.6 0.3 15 5.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KFP16326.1 - 0.054 13.1 0.2 3.7 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KFP16326.1 - 0.075 13.6 0.9 1.1 9.8 0.0 3.6 3 0 0 3 3 2 0 AAA domain DUF2935 PF11155.8 KFP16326.1 - 0.63 10.4 7.0 2 8.8 1.3 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF2935) Exonuc_VII_L PF02601.15 KFP16326.1 - 4.3 6.8 16.6 0.49 9.9 0.3 3.6 3 0 0 3 3 3 0 Exonuclease VII, large subunit Ank_2 PF12796.7 KFP16327.1 - 3.3e-46 155.8 11.6 9.4e-15 55.0 0.0 6.2 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP16327.1 - 2.4e-38 130.0 11.2 2e-10 41.0 0.0 8.1 4 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP16327.1 - 3.9e-38 125.1 12.3 0.00033 20.9 0.0 11.2 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 KFP16327.1 - 1.1e-31 107.8 11.7 6.5e-05 23.2 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFP16327.1 - 5.1e-18 64.9 16.6 2e-05 24.8 0.0 8.5 3 2 7 10 10 10 6 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP16327.1 - 9.9e-12 45.0 6.5 4.5e-11 42.9 6.5 2.1 2 0 0 2 2 2 1 SOCS box BAR_3 PF16746.5 KFP16328.1 - 3.3e-56 190.7 13.1 3.3e-56 190.7 13.1 2.2 2 0 0 2 2 2 1 BAR domain of APPL family PID PF00640.23 KFP16328.1 - 7.8e-12 45.4 0.0 7.8e-12 45.4 0.0 3.4 3 1 1 4 4 4 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.29 KFP16328.1 - 2e-07 31.5 0.1 7.1e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 PH domain PTB PF08416.13 KFP16328.1 - 0.0076 16.4 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PH_9 PF15410.6 KFP16328.1 - 0.0098 16.3 0.6 0.068 13.5 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Gemin6 PF06372.12 KFP16328.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Gemin6 protein DUF1664 PF07889.12 KFP16328.1 - 0.45 10.6 8.4 7.3 6.6 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFP16328.1 - 0.46 10.5 1.9 1.2 9.1 0.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Homeodomain PF00046.29 KFP16329.1 - 2.9e-24 84.7 2.5 5.9e-24 83.7 1.3 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP16329.1 - 0.0025 17.7 0.1 0.0061 16.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain IL17R_D_N PF16742.5 KFP16330.1 - 7.1e-66 219.8 0.1 1.5e-65 218.8 0.1 1.6 1 0 0 1 1 1 1 N-terminus of interleukin 17 receptor D SEFIR PF08357.11 KFP16330.1 - 6.6e-57 192.0 1.0 1.4e-56 191.0 1.0 1.6 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 KFP16330.1 - 0.0012 19.5 0.0 0.0034 18.0 0.0 1.9 1 1 0 1 1 1 1 TIR domain fn3 PF00041.21 KFP16330.1 - 0.017 15.5 0.0 5 7.6 0.0 2.8 3 0 0 3 3 3 0 Fibronectin type III domain DUF2141 PF09912.9 KFP16330.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) RhoGEF PF00621.20 KFP16331.1 - 4.5e-38 131.3 0.3 8.3e-38 130.4 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 KFP16331.1 - 7.8e-07 29.3 0.4 8.1e-06 26.0 0.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFP16331.1 - 0.00032 20.6 0.2 0.0042 16.9 0.1 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFP16331.1 - 0.00069 20.1 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 KFP16331.1 - 0.072 12.9 0.6 1.4 8.8 0.6 2.4 1 1 0 1 1 1 0 PH domain zf-Di19 PF05605.12 KFP16331.1 - 0.99 9.8 3.6 0.37 11.1 0.4 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CCDC66 PF15236.6 KFP16332.1 - 3.4e-50 169.8 39.0 3.4e-50 169.8 39.0 4.7 4 2 0 4 4 4 1 Coiled-coil domain-containing protein 66 wnt PF00110.19 KFP16335.1 - 2.9e-121 404.8 23.9 3.3e-121 404.6 23.9 1.0 1 0 0 1 1 1 1 wnt family EndoU_bacteria PF14436.6 KFP16335.1 - 0.15 12.4 0.0 0.51 10.7 0.0 1.8 1 1 0 1 1 1 0 Bacterial EndoU nuclease K_channel_TID PF07941.11 KFP16335.1 - 3.3 8.2 6.8 1.4 9.4 0.2 2.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain VGCC_alpha2 PF08473.11 KFP16336.1 - 3.8e-28 98.5 8.8 9.9e-28 97.1 8.2 2.0 2 1 0 2 2 2 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 KFP16336.1 - 7.9e-28 97.4 0.4 1.8e-27 96.3 0.4 1.7 1 0 0 1 1 1 1 VWA N-terminal dCache_1 PF02743.18 KFP16336.1 - 3.6e-15 56.4 2.2 2e-11 44.1 0.2 3.6 2 2 1 3 3 3 2 Cache domain VWA_3 PF13768.6 KFP16336.1 - 4.4e-14 52.7 0.0 9.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFP16336.1 - 5.3e-12 46.3 0.1 1e-11 45.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP16336.1 - 1.3e-09 38.6 0.0 2.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_2 PF08269.11 KFP16336.1 - 0.0011 18.2 0.1 0.0042 16.3 0.1 1.9 2 0 0 2 2 2 1 Cache domain Cache_3-Cache_2 PF17201.4 KFP16336.1 - 0.0078 15.5 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain VWA_CoxE PF05762.14 KFP16336.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein LRR_8 PF13855.6 KFP16337.1 - 6.1e-25 86.8 19.9 1.5e-16 59.9 4.9 4.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP16337.1 - 6.1e-09 36.0 21.5 0.00063 20.1 3.3 3.6 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP16337.1 - 1.2e-08 34.9 0.4 1e-06 28.8 0.5 2.2 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP16337.1 - 1.3e-08 34.6 6.5 0.00029 20.4 0.9 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP16337.1 - 1.7e-05 24.7 12.9 0.046 14.3 0.2 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRRNT PF01462.18 KFP16337.1 - 0.014 15.0 1.4 0.014 15.0 1.4 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP16337.1 - 0.042 13.9 14.3 0.16 12.1 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat SelK_SelG PF10961.8 KFP16339.1 - 5e-26 91.1 0.5 5.6e-26 91.0 0.5 1.0 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Actin PF00022.19 KFP16340.1 - 7e-30 103.9 0.0 1.2e-27 96.6 0.0 2.5 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 KFP16340.1 - 2.5e-15 56.6 0.1 5.9e-08 32.3 0.1 2.1 2 0 0 2 2 2 2 Putative actin-like family GMC_oxred_N PF00732.19 KFP16342.1 - 4.9e-95 318.3 0.0 6.7e-95 317.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFP16342.1 - 5.3e-41 140.5 0.0 8.6e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFP16342.1 - 2.6e-05 23.5 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFP16342.1 - 0.00032 20.4 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFP16342.1 - 0.0011 18.2 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KFP16342.1 - 0.0028 16.9 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFP16342.1 - 0.0028 17.8 0.0 0.0084 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFP16342.1 - 0.035 13.3 0.0 0.076 12.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ion_trans PF00520.31 KFP16343.1 - 9.1e-254 837.2 83.7 1e-70 237.7 14.2 4.1 4 0 0 4 4 4 4 Ion transport protein CAC1F_C PF16885.5 KFP16343.1 - 2e-74 251.5 2.6 2e-74 251.5 2.6 2.6 2 0 0 2 2 2 1 Voltage-gated calcium channel subunit alpha, C-term Ca_chan_IQ PF08763.11 KFP16343.1 - 6.9e-31 106.3 0.2 1.6e-30 105.1 0.2 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KFP16343.1 - 1.1e-28 98.7 0.1 3.4e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KFP16343.1 - 4.1e-11 42.2 81.5 4.7e-10 38.7 7.0 9.5 7 3 2 9 9 9 3 Polycystin cation channel DUF4834 PF16118.5 KFP16343.1 - 0.028 15.4 0.2 0.028 15.4 0.2 8.9 10 0 0 10 10 10 0 Domain of unknown function (DUF4834) Rer1 PF03248.13 KFP16343.1 - 0.053 13.3 9.3 0.32 10.7 2.5 4.4 4 0 0 4 4 4 0 Rer1 family DUF5305 PF17231.2 KFP16343.1 - 0.068 12.6 0.4 3.4 7.0 0.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5305) NARP1 PF12569.8 KFP16343.1 - 1.1 8.1 6.4 2.3 7.0 6.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EphA2_TM PF14575.6 KFP16343.1 - 5.2 8.0 6.8 32 5.5 0.1 5.6 6 0 0 6 6 6 0 Ephrin type-A receptor 2 transmembrane domain DCP1 PF06058.13 KFP16344.1 - 8e-27 93.5 0.0 1.8e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KFP16344.1 - 9.2e-22 76.1 1.4 1.8e-21 75.1 1.4 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus Transket_pyr PF02779.24 KFP16345.1 - 8.2e-41 139.6 0.0 1.9e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.21 KFP16345.1 - 3.8e-39 134.6 0.0 7.2e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KFP16345.1 - 2.9e-32 111.2 0.4 5.7e-32 110.2 0.4 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KFP16345.1 - 1.3e-07 30.8 0.0 4.6e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFP16345.1 - 4.4e-06 26.5 0.2 0.00017 21.4 0.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KFP16345.1 - 7e-05 22.2 0.0 0.0022 17.2 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KFP16345.1 - 0.0014 17.5 0.1 0.0091 14.8 0.0 1.9 1 1 1 2 2 2 1 XFP N-terminal domain RVT_1 PF00078.27 KFP16346.1 - 0.017 14.6 0.1 0.041 13.4 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FancD2 PF14631.6 KFP16347.1 - 0 2394.7 18.2 0 2394.4 18.2 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 KFP16347.1 - 0.00038 20.8 0.2 0.00038 20.8 0.2 4.4 5 1 0 6 6 6 1 FANCI solenoid 2 EMC3_TMCO1 PF01956.16 KFP16348.1 - 1.5e-36 125.7 4.1 3.3e-36 124.6 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like Ras PF00071.22 KFP16349.1 - 8.4e-58 194.5 0.0 1e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16349.1 - 3.3e-23 82.2 0.0 4.4e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16349.1 - 6e-09 35.6 0.0 2.1e-08 33.8 0.0 1.7 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP16349.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP16349.1 - 0.043 13.2 0.0 0.073 12.5 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP16349.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KFP16349.1 - 0.22 11.3 0.0 2.6 7.8 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GyrI-like PF06445.15 KFP16350.1 - 0.028 14.7 0.1 0.073 13.4 0.0 1.7 2 0 0 2 2 2 0 GyrI-like small molecule binding domain ANF_receptor PF01094.28 KFP16351.1 - 1e-99 334.0 0.1 1.3e-99 333.7 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP16351.1 - 2.9e-61 207.2 16.7 4.6e-61 206.6 16.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP16351.1 - 1.6e-12 47.2 10.1 1.6e-12 47.2 10.1 2.6 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP16351.1 - 1.2e-09 38.3 0.4 3.6e-09 36.8 0.8 1.4 2 0 0 2 2 2 1 Periplasmic binding protein DUF543 PF04418.12 KFP16351.1 - 0.0063 16.5 0.3 1.3 9.1 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF543) DUF4199 PF13858.6 KFP16351.1 - 0.01 16.2 1.4 2.7 8.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) WD40 PF00400.32 KFP16352.1 - 4.8e-34 115.8 10.7 3e-06 27.8 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16352.1 - 5e-06 26.7 0.1 0.066 13.5 0.0 4.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP16352.1 - 0.047 13.0 0.0 1.4 8.2 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain OAS1_C PF10421.9 KFP16354.1 - 3.7e-70 235.2 0.0 8.3e-70 234.0 0.0 1.5 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.23 KFP16354.1 - 5.4e-33 112.6 0.7 1.2e-21 76.3 0.2 3.1 3 1 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 KFP16354.1 - 9.7e-12 44.6 0.1 1.9e-08 34.0 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFP16354.1 - 1.7e-09 38.0 0.3 0.0011 19.4 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin-like domain NTP_transf_2 PF01909.23 KFP16354.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 KFP16354.1 - 6.6e-05 23.1 0.1 0.00019 21.7 0.0 1.7 2 0 0 2 2 2 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Ubiquitin_4 PF18036.1 KFP16354.1 - 0.00011 22.1 0.2 0.065 13.3 0.0 3.4 2 2 2 4 4 4 1 Ubiquitin-like domain DUF1405 PF07187.11 KFP16354.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) Sema PF01403.19 KFP16355.1 - 5.5e-102 341.7 0.0 6.6e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP16355.1 - 0.0042 17.6 6.1 0.0042 17.6 6.1 1.7 2 0 0 2 2 2 1 Plexin repeat Aa_trans PF01490.18 KFP16356.1 - 4.4e-07 28.9 1.8 5.2e-07 28.7 1.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein G-alpha PF00503.20 KFP16357.1 - 3.4e-117 391.6 3.9 3.9e-117 391.4 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP16357.1 - 1e-13 51.2 0.1 9.4e-13 48.0 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP16358.1 - 2.7e-120 401.7 1.8 3.3e-120 401.5 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP16358.1 - 2.3e-14 53.2 2.6 1.1e-10 41.3 0.3 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP16358.1 - 0.00054 19.4 0.6 0.54 9.6 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP16358.1 - 0.002 18.3 1.1 1.4 9.1 0.1 2.7 1 1 2 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP16358.1 - 0.034 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 KFP16358.1 - 0.11 11.7 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KFP16358.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sema PF01403.19 KFP16359.1 - 2.7e-136 454.8 0.0 3.2e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP16359.1 - 0.002 18.6 7.5 0.0064 17.0 7.5 2.0 1 0 0 1 1 1 1 Plexin repeat KH_1 PF00013.29 KFP16360.1 - 9.7e-51 169.5 13.1 1.2e-17 63.4 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFP16360.1 - 1.9e-14 53.3 4.8 9.7e-05 22.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFP16360.1 - 5.7e-08 32.5 1.8 0.011 15.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFP16360.1 - 3.2e-05 23.9 5.1 1.2 9.3 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFP16360.1 - 0.00091 19.2 0.1 0.028 14.4 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain Abhydrolase_1 PF00561.20 KFP16361.1 - 3e-08 33.6 0.0 0.0065 16.2 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP16361.1 - 9.8e-07 29.6 1.2 0.0029 18.2 0.5 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP16361.1 - 0.0012 18.2 0.1 0.14 11.4 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KFP16361.1 - 0.04 13.5 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_M20 PF01546.28 KFP16362.1 - 1.3e-35 123.0 0.0 1.8e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFP16362.1 - 5.3e-13 48.8 0.0 9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFP16362.1 - 1.8e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sema PF01403.19 KFP16363.1 - 2.4e-144 481.3 0.0 3.1e-144 480.9 0.0 1.1 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFP16363.1 - 0.0001 22.4 0.1 0.00041 20.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KFP16363.1 - 0.00014 22.0 0.1 0.0084 16.3 0.1 2.8 2 1 0 2 2 2 1 Immunoglobulin V-set domain PSI PF01437.25 KFP16363.1 - 0.00061 20.3 7.2 0.0014 19.1 7.2 1.6 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.16 KFP16363.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP16363.1 - 0.0014 19.2 0.0 0.0041 17.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFP16363.1 - 0.0014 18.1 0.0 0.0037 16.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Peptidase_C12 PF01088.21 KFP16364.1 - 2.1e-63 213.9 0.0 4.8e-63 212.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFP16364.1 - 6.5e-17 61.2 0.1 1.7e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Nucleo_P87 PF07267.11 KFP16364.1 - 0.25 10.2 8.5 0.44 9.3 8.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ORC6 PF05460.13 KFP16364.1 - 6.4 5.9 13.6 0.85 8.8 0.0 2.3 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) HAUS-augmin3 PF14932.6 KFP16365.1 - 1.3e-84 283.9 11.8 1.3e-84 283.9 11.8 3.8 3 1 0 4 4 4 1 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 KFP16365.1 - 0.0019 17.7 3.1 0.0019 17.7 3.1 4.1 3 1 1 4 4 4 3 Golgin subfamily A member 5 DUF2129 PF09902.9 KFP16365.1 - 0.14 12.2 1.1 0.52 10.4 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) CheZ PF04344.13 KFP16365.1 - 3.9 7.3 19.0 0.09 12.7 1.6 4.0 4 0 0 4 4 4 0 Chemotaxis phosphatase, CheZ DUF4147 PF13660.6 KFP16366.1 - 2.6e-78 262.7 0.9 3.8e-78 262.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 KFP16366.1 - 6.9e-37 126.0 0.3 1.3e-36 125.1 0.3 1.5 1 0 0 1 1 1 1 MOFRL family Cofilin_ADF PF00241.20 KFP16367.1 - 8.2e-42 141.8 0.6 2e-22 79.2 0.5 2.7 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 KFP16367.1 - 3.2e-17 62.6 0.9 3.7e-05 24.4 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16367.1 - 5.1e-10 39.5 0.0 0.00081 19.6 0.0 3.9 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MinC_C PF03775.16 KFP16367.1 - 0.18 11.8 0.0 0.63 10.1 0.0 1.9 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain PD40 PF07676.12 KFP16367.1 - 1.1 9.3 5.0 15 5.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PP2C PF00481.21 KFP16368.1 - 1.4e-32 113.4 0.0 8.6e-15 55.1 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KFP16368.1 - 5.4e-05 23.2 0.0 0.072 13.0 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFP16368.1 - 0.099 12.3 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C Aminotran_1_2 PF00155.21 KFP16369.1 - 3.4e-79 266.7 0.0 4.3e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 KFP16369.1 - 9.3e-19 68.0 2.5 2e-18 67.0 2.5 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.20 KFP16369.1 - 1.9e-07 30.0 0.0 1.2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFP16369.1 - 1.7e-05 23.9 0.0 3.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP16369.1 - 0.00063 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFP16369.1 - 0.016 14.5 1.0 0.072 12.4 1.0 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.32 KFP16370.1 - 2.8e-65 214.7 20.0 1.5e-09 38.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16370.1 - 2.3e-23 82.3 0.1 0.00039 20.6 0.0 6.7 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP16370.1 - 1.6e-11 43.8 3.3 0.0072 15.3 0.1 5.0 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP16370.1 - 3.3e-10 40.2 0.1 9.5e-06 25.6 0.0 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFP16370.1 - 0.00013 20.6 0.1 0.76 8.2 0.1 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KFP16370.1 - 0.0023 17.6 0.4 1 9.1 0.0 3.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KFP16370.1 - 0.013 14.2 7.3 4.7 5.7 0.0 4.3 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFP16370.1 - 0.013 14.2 0.4 0.071 11.8 0.3 2.2 2 1 0 2 2 2 0 Nup133 N terminal like PD40 PF07676.12 KFP16370.1 - 0.031 14.2 0.4 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KFP16370.1 - 0.051 12.9 0.0 24 4.1 0.0 3.8 3 2 1 4 4 4 0 WD40-like domain Syntaxin-6_N PF09177.11 KFP16370.1 - 0.065 13.8 1.1 0.13 12.9 1.1 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DSPc PF00782.20 KFP16371.1 - 1.9e-43 147.5 0.0 2.5e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP16371.1 - 0.00034 20.3 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP16371.1 - 0.0053 17.0 0.0 0.0087 16.4 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KFP16371.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate HSF_DNA-bind PF00447.17 KFP16372.1 - 8.8e-23 80.7 0.1 1.1e-22 80.5 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding EF-hand_8 PF13833.6 KFP16373.1 - 5.1e-28 96.7 15.0 3.9e-15 55.4 0.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KFP16373.1 - 1.7e-27 95.7 9.8 2.7e-16 59.8 6.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP16373.1 - 4.9e-26 88.3 23.9 3.3e-08 32.5 1.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFP16373.1 - 7.3e-21 72.3 15.4 2.8e-07 29.9 1.9 5.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP16373.1 - 1.8e-15 55.7 20.1 1.1e-06 27.8 0.3 4.9 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 KFP16373.1 - 5.5e-13 49.0 1.0 3.4e-06 27.3 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP16373.1 - 1.1e-06 28.5 6.7 0.012 15.5 0.1 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KFP16373.1 - 5.2e-05 23.5 1.4 0.0016 18.8 0.4 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFP16373.1 - 0.00099 19.1 0.1 1.2 9.1 0.0 2.3 1 1 0 2 2 2 2 Tellurite resistance protein TerB DUF1707 PF08044.11 KFP16373.1 - 0.0031 17.5 0.8 1.1 9.4 0.1 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF1707) UPF0154 PF03672.13 KFP16373.1 - 0.0056 16.7 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) DUF1456 PF07308.13 KFP16373.1 - 0.02 15.2 1.8 2.3 8.6 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) DUF5580 PF17743.1 KFP16373.1 - 0.02 13.4 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 KFP16373.1 - 0.031 14.2 3.7 0.12 12.2 0.7 2.8 2 1 1 3 3 3 0 EF hand EMG1 PF03587.14 KFP16373.1 - 0.077 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Syntaxin PF00804.25 KFP16373.1 - 0.18 11.4 2.2 2.2 7.9 0.3 2.3 2 0 0 2 2 2 0 Syntaxin PX PF00787.24 KFP16374.1 - 2e-19 69.6 2.0 2.4e-19 69.4 2.0 1.0 1 0 0 1 1 1 1 PX domain EBV-NA3 PF05009.12 KFP16374.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) 5_nucleotid PF05761.14 KFP16376.1 - 1.9e-141 472.1 4.5 2.4e-141 471.8 4.5 1.1 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFP16376.1 - 0.0023 18.0 1.2 0.035 14.2 1.8 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UPF0640 PF15114.6 KFP16377.1 - 1.7e-35 120.6 2.6 1.9e-35 120.5 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 Bromodomain PF00439.25 KFP16378.1 - 1.7e-113 370.9 28.8 3.4e-23 81.5 0.1 6.8 6 0 0 6 6 6 6 Bromodomain BAH PF01426.18 KFP16378.1 - 1.1e-54 183.5 3.7 6.5e-29 100.3 1.4 3.0 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 KFP16378.1 - 2.7e-14 53.3 0.6 2.7e-14 53.3 0.6 2.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP16378.1 - 1.5e-10 41.5 1.3 4.9e-10 39.9 1.3 1.9 1 0 0 1 1 1 1 HMG-box domain GN3L_Grn1 PF08701.11 KFP16379.1 - 4.2e-20 71.6 28.3 4.2e-20 71.6 28.3 3.8 2 1 2 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KFP16379.1 - 2e-12 47.2 0.1 1.8e-10 40.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP16379.1 - 3.9e-06 26.5 0.3 8.6e-05 22.1 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KFP16379.1 - 0.021 13.8 0.1 0.021 13.8 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KFP16379.1 - 0.092 12.6 8.7 0.3 11.0 0.3 2.8 2 1 1 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 KFP16379.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.5 3 1 0 3 3 3 0 Dynamin family DUF2291 PF10054.9 KFP16379.1 - 0.15 11.7 2.2 0.31 10.7 2.2 1.4 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) TFIIA PF03153.13 KFP16379.1 - 0.56 10.1 18.9 0.03 14.3 4.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 KFP16379.1 - 1.8 6.7 21.0 0.8 7.9 2.5 2.3 2 0 0 2 2 2 0 CDC45-like protein Hus1 PF04005.12 KFP16379.1 - 2 7.5 7.9 0.038 13.1 0.6 1.8 2 0 0 2 2 2 0 Hus1-like protein CENP-B_dimeris PF09026.10 KFP16379.1 - 4 7.9 13.2 10 6.6 13.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_transf_8 PF01501.20 KFP16380.1 - 2.9e-58 197.4 0.1 3.4e-58 197.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP16380.1 - 0.0021 17.5 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_tranf_2_3 PF13641.6 KFP16380.1 - 0.014 15.3 0.3 5.9 6.7 0.1 2.7 3 1 0 3 3 3 0 Glycosyltransferase like family 2 Synapsin_N PF10581.9 KFP16380.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Synapsin N-terminal SPC12 PF06645.13 KFP16381.1 - 2.6e-31 107.5 1.0 3e-31 107.3 1.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 KFP16381.1 - 0.0019 17.2 0.0 0.002 17.1 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.8 KFP16381.1 - 0.039 13.5 0.4 0.048 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) LapA_dom PF06305.11 KFP16381.1 - 1.1 9.1 4.1 6.2 6.7 0.7 2.2 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KFP16382.1 - 5e-58 196.5 0.1 1.5e-57 194.9 0.1 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16382.1 - 1.7e-48 165.2 0.1 3.3e-48 164.2 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP16382.1 - 0.00016 21.1 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP16382.1 - 0.00057 18.8 0.0 0.00057 18.8 0.0 2.8 3 1 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 KFP16382.1 - 0.057 12.8 0.1 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP16382.1 - 0.12 12.3 0.1 0.8 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFP16382.1 - 0.71 9.4 3.3 5 6.6 0.0 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ITI_HC_C PF06668.12 KFP16383.1 - 3e-72 242.3 0.1 5.3e-72 241.5 0.1 1.4 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.10 KFP16383.1 - 3.7e-32 110.8 3.7 8.1e-32 109.7 3.7 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KFP16383.1 - 2.2e-20 73.6 0.0 4.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP16383.1 - 2.5e-13 50.3 0.0 3.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP16383.1 - 3.1e-11 43.9 0.0 8.5e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KFP16383.1 - 0.00037 20.7 0.0 0.00067 19.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 KFP16383.1 - 0.035 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Mustang PF15682.5 KFP16384.1 - 5.1e-41 138.6 3.4 5.5e-41 138.5 3.4 1.0 1 0 0 1 1 1 1 Musculoskeletal, temporally activated-embryonic nuclear protein 1 MBT PF02820.18 KFP16386.1 - 1.5e-90 297.6 1.0 4.4e-22 78.2 0.0 4.6 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 KFP16386.1 - 9e-40 135.7 0.0 2.2e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFP16386.1 - 4.5e-10 39.8 0.0 8.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP16386.1 - 7.2e-07 29.2 0.0 2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP16386.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 KFP16386.1 - 0.0072 16.6 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Agenet PF05641.12 KFP16386.1 - 0.025 15.0 0.7 5 7.7 0.0 3.6 3 0 0 3 3 3 0 Agenet domain Nucleo_P87 PF07267.11 KFP16386.1 - 2.7 6.7 8.3 3.9 6.2 8.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4637 PF15470.6 KFP16386.1 - 6.6 6.4 10.1 16 5.2 10.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Rft-1 PF04506.13 KFP16387.1 - 5.4e-142 474.1 25.9 6.2e-142 473.9 25.9 1.0 1 0 0 1 1 1 1 Rft protein Phtf-FEM1B_bdg PF12129.8 KFP16387.1 - 0.049 13.5 2.2 0.2 11.5 2.2 2.1 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor CDC48_2 PF02933.17 KFP16387.1 - 0.11 12.2 0.3 2.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Sec62 PF03839.16 KFP16387.1 - 5.2 6.5 10.8 1.1 8.7 6.6 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Pkinase PF00069.25 KFP16389.1 - 3e-61 207.1 0.0 4.3e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16389.1 - 1.3e-37 129.5 0.0 2.6e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP16389.1 - 7.7e-32 109.0 20.4 3.6e-17 62.0 7.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFP16389.1 - 1.2e-08 35.6 1.7 2.2e-08 34.7 1.7 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 KFP16389.1 - 3.5e-05 24.0 13.8 0.0012 19.1 3.1 2.5 2 0 0 2 2 2 2 C1 domain Kinase-like PF14531.6 KFP16389.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.11 KFP16389.1 - 0.00068 19.9 19.2 0.043 14.1 6.7 2.7 2 0 0 2 2 2 2 RING-like domain Zf_RING PF16744.5 KFP16389.1 - 0.0028 17.8 9.3 0.0029 17.7 1.5 2.4 2 0 0 2 2 2 1 KIAA1045 RING finger Haspin_kinase PF12330.8 KFP16389.1 - 0.019 13.9 0.1 0.044 12.7 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 KFP16389.1 - 0.02 14.9 14.2 0.23 11.4 4.0 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFP16389.1 - 0.023 14.6 18.3 0.091 12.7 3.5 2.6 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 KFP16389.1 - 0.041 14.0 10.8 0.041 14.0 1.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Pkinase_fungal PF17667.1 KFP16389.1 - 0.049 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Spore_YhaL PF14147.6 KFP16389.1 - 0.064 13.0 0.3 0.48 10.1 0.1 2.4 2 0 0 2 2 2 0 Sporulation protein YhaL APH PF01636.23 KFP16389.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DZR PF12773.7 KFP16389.1 - 0.15 12.1 12.6 0.46 10.6 2.7 2.7 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 KFP16389.1 - 0.22 11.5 13.0 1.7 8.6 3.0 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CxC3 PF18804.1 KFP16389.1 - 0.78 9.6 6.0 1 9.2 0.5 3.0 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases PADR1 PF08063.12 KFP16389.1 - 2 8.2 12.1 0.052 13.3 2.8 2.7 2 0 0 2 2 2 0 PADR1 (NUC008) domain FYVE_2 PF02318.16 KFP16389.1 - 4.6 7.5 11.1 2.7 8.2 2.0 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-ACC PF17848.1 KFP16389.1 - 5.7 7.1 10.6 29 4.9 2.6 3.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain 6PF2K PF01591.18 KFP16390.1 - 2.2e-102 341.1 1.5 2.7e-102 340.8 0.8 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFP16390.1 - 9.2e-43 146.2 0.0 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFP16390.1 - 8e-08 32.6 0.0 2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KFP16390.1 - 0.00097 18.7 0.1 0.002 17.7 0.1 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Prefoldin PF02996.17 KFP16390.1 - 0.0016 18.3 1.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit AAA_18 PF13238.6 KFP16390.1 - 0.013 16.0 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 KFP16390.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Zeta_toxin PF06414.12 KFP16390.1 - 0.085 12.1 0.0 0.25 10.6 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin TUSC2 PF15000.6 KFP16391.1 - 4.9e-33 113.7 0.1 5.4e-33 113.6 0.1 1.0 1 0 0 1 1 1 1 Tumour suppressor candidate 2 zf-MYND PF01753.18 KFP16392.1 - 1.8e-09 37.5 19.5 1.8e-09 37.5 19.5 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KFP16392.1 - 0.88 9.5 8.0 1.6 8.6 8.0 1.5 1 0 0 1 1 1 0 HIT zinc finger NPR2 PF06218.11 KFP16393.1 - 2.4e-77 260.6 7.2 2.9e-62 210.9 4.2 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DUF2738 PF10927.8 KFP16393.1 - 0.17 11.0 0.6 0.22 10.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2738) Cytochrom_B561 PF03188.16 KFP16394.1 - 3.7e-33 114.6 6.1 5.8e-33 113.9 6.1 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 IPTL-CTERM PF18203.1 KFP16394.1 - 7.9 6.5 11.5 0.39 10.7 4.9 2.3 2 0 0 2 2 2 0 IPTL-CTERM motif DUF1751 PF08551.10 KFP16395.1 - 0.00014 22.4 0.4 0.00014 22.4 0.4 2.1 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) SpoIIM PF01944.17 KFP16395.1 - 0.031 14.3 3.6 0.057 13.5 3.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein M VGCC_alpha2 PF08473.11 KFP16396.1 - 2.2e-137 458.4 0.8 2.1e-132 442.0 0.3 2.0 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA PF00092.28 KFP16397.1 - 1.8e-09 38.1 0.0 2.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP16397.1 - 4.5e-05 23.4 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP16397.1 - 0.0081 16.8 0.0 0.032 14.9 0.0 1.8 1 1 1 2 2 2 1 von Willebrand factor type A domain Gram_pos_anchor PF00746.21 KFP16400.1 - 0.053 13.5 0.2 0.081 12.9 0.2 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LapA_dom PF06305.11 KFP16400.1 - 0.088 12.6 0.3 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CEP19 PF14933.6 KFP16400.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein MTS PF05175.14 KFP16401.1 - 3e-13 49.7 0.0 1.7e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 KFP16401.1 - 1.7e-09 38.1 0.0 3.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 KFP16401.1 - 6.7e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP16401.1 - 2.3e-08 33.9 0.0 5.6e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFP16401.1 - 3.4e-08 34.1 0.0 7.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP16401.1 - 3.6e-08 33.1 0.0 6.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFP16401.1 - 2.5e-05 24.9 0.0 4.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFP16401.1 - 2.6e-05 23.8 0.0 0.00012 21.6 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase UPF0020 PF01170.18 KFP16401.1 - 0.00011 22.0 0.1 0.00037 20.2 0.0 1.8 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KFP16401.1 - 0.00039 21.0 0.0 0.00073 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFP16401.1 - 0.0025 18.8 0.0 0.0055 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KFP16401.1 - 0.0026 17.5 0.0 0.033 13.9 0.0 2.2 2 1 0 2 2 2 1 DNA methylase Methyltr_RsmB-F PF01189.17 KFP16401.1 - 0.0027 17.4 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 KFP16401.1 - 0.0028 17.6 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFP16401.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KFP16401.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KFP16401.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_15 PF09445.10 KFP16401.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase PRMT5 PF05185.16 KFP16401.1 - 0.046 13.6 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 KFP16401.1 - 0.052 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KFP16401.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.12 KFP16401.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SH2 PF00017.24 KFP16403.1 - 1.4e-13 50.8 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFP16403.1 - 3.1e-12 46.6 0.7 1.1e-11 44.8 0.7 2.0 1 0 0 1 1 1 1 SOCS box SH2_2 PF14633.6 KFP16403.1 - 0.19 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Pkinase PF00069.25 KFP16404.1 - 8.3e-69 231.9 0.0 1.4e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16404.1 - 2.9e-29 102.2 0.0 4.4e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP16404.1 - 1.7e-07 30.8 0.2 3.2e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP16404.1 - 0.0022 17.4 0.0 0.0056 16.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP16404.1 - 0.0028 16.5 0.0 0.0074 15.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase VF530 PF09905.9 KFP16404.1 - 0.048 13.9 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 DNA-binding protein VF530 PAXIP1_C PF15364.6 KFP16404.1 - 0.055 13.8 0.7 0.33 11.3 0.2 2.4 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein Choline_kinase PF01633.20 KFP16404.1 - 0.1 12.2 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DHR-2 PF06920.13 KFP16406.1 - 3.4e-133 445.1 5.8 3.4e-133 445.1 5.8 2.4 3 0 0 3 3 3 1 Dock homology region 2 DOCK_N PF16172.5 KFP16406.1 - 1.9e-100 336.5 0.5 3.2e-100 335.7 0.5 1.4 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFP16406.1 - 2.4e-56 190.6 0.0 6.2e-56 189.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SPOC PF07744.13 KFP16408.1 - 4.2e-36 124.1 0.0 6.1e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFP16408.1 - 1.2e-25 89.0 0.0 2e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP16408.1 - 0.00025 21.0 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFP16408.1 - 0.0013 18.7 0.0 0.0074 16.3 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFP16408.1 - 0.034 14.3 0.0 3.3 7.9 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Nab6_mRNP_bdg PF10567.9 KFP16408.1 - 0.22 11.0 1.2 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 RNA-recognition motif SOBP PF15279.6 KFP16408.1 - 0.47 11.0 8.0 0.66 10.5 8.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein LisH PF08513.11 KFP16409.1 - 0.017 15.1 0.1 0.2 11.7 0.0 2.7 3 0 0 3 3 3 0 LisH ANAPC4_WD40 PF12894.7 KFP16409.1 - 0.065 13.5 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF913 PF06025.12 KFP16409.1 - 7.7 5.4 8.4 20 4.0 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Sema PF01403.19 KFP16410.1 - 4.6e-122 407.9 0.0 1.2e-69 235.3 0.0 2.1 2 0 0 2 2 2 2 Sema domain Ig_3 PF13927.6 KFP16410.1 - 9.7e-05 22.9 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP16410.1 - 0.00053 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP16410.1 - 0.0035 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain PSI PF01437.25 KFP16410.1 - 0.0059 17.1 9.6 0.0059 17.1 9.6 2.4 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.6 KFP16410.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP16410.1 - 0.07 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain OCRE PF17780.1 KFP16411.1 - 9e-23 80.1 1.8 1.9e-22 79.0 1.8 1.6 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 KFP16411.1 - 0.00032 20.5 3.0 0.001 18.9 3.0 2.0 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP16411.1 - 0.011 15.8 1.6 0.059 13.5 1.6 2.3 1 0 0 1 1 1 0 G-patch domain zf-C2H2_jaz PF12171.8 KFP16411.1 - 0.11 12.8 0.3 0.35 11.2 0.3 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Mon1 PF03164.14 KFP16412.1 - 8.3e-144 479.6 0.2 9.4e-144 479.4 0.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Chisel PF15355.6 KFP16412.1 - 0.23 11.7 0.4 19 5.6 0.1 2.5 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel 7tm_4 PF13853.6 KFP16413.1 - 6.5e-39 134.3 17.0 7.6e-39 134.1 17.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16413.1 - 2.1e-29 102.7 15.3 3.5e-29 102.0 15.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16413.1 - 0.00032 20.2 13.1 0.00055 19.4 13.1 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP16413.1 - 0.11 12.1 15.2 0.22 11.1 14.4 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP16414.1 - 2e-51 175.4 10.4 2.3e-51 175.2 10.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16414.1 - 3.5e-30 105.2 12.2 4.6e-30 104.8 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16414.1 - 0.00084 18.8 12.1 0.0013 18.2 10.0 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx CholecysA-Rec_N PF09193.10 KFP16414.1 - 0.084 12.9 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal Baculo_11_kDa PF06143.11 KFP16414.1 - 0.19 11.3 1.5 0.48 10.0 1.5 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family 7tm_4 PF13853.6 KFP16415.1 - 1.1e-47 163.2 15.3 1.3e-47 162.9 15.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16415.1 - 3e-29 102.2 20.2 5e-29 101.4 20.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP16416.1 - 1.8e-40 139.4 14.6 2.2e-40 139.2 14.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16416.1 - 6e-30 104.4 12.9 7.8e-30 104.1 12.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP16416.1 - 0.0028 17.3 7.9 0.0028 17.3 7.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP16416.1 - 0.06 12.7 12.2 0.12 11.7 12.2 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3487 PF11990.8 KFP16416.1 - 0.54 10.2 0.0 0.54 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Tetraspanin PF00335.20 KFP16417.1 - 1e-35 123.6 9.0 1.1e-35 123.4 9.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 KFP16417.1 - 0.022 14.5 0.1 0.022 14.5 0.1 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Cys_knot PF00007.22 KFP16418.1 - 2.6e-30 104.8 14.5 3e-30 104.6 14.5 1.0 1 0 0 1 1 1 1 Cystine-knot domain SCP-1 PF05483.12 KFP16419.1 - 6.7e-214 712.3 164.1 1.9e-212 707.4 164.1 2.4 1 1 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) UPF0242 PF06785.11 KFP16419.1 - 0.0025 18.0 17.0 0.0025 18.0 17.0 7.6 2 1 6 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus DUF4181 PF13789.6 KFP16419.1 - 0.47 10.7 1.4 1.5 9.1 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) CSD PF00313.22 KFP16420.1 - 2.3e-82 270.8 16.4 7.3e-17 61.0 0.1 9.1 9 0 0 9 9 9 5 'Cold-shock' DNA-binding domain S1-like PF14444.6 KFP16420.1 - 3.6e-13 49.2 10.8 0.053 13.5 0.0 7.4 7 0 0 7 7 7 4 S1-like SUZ-C PF12901.7 KFP16420.1 - 1.1e-11 44.4 0.9 5.7e-11 42.2 0.1 2.4 2 0 0 2 2 2 1 SUZ-C motif CusF_Ec PF11604.8 KFP16420.1 - 2.9e-09 36.8 7.1 0.066 13.2 0.0 7.6 8 0 0 8 8 8 3 Copper binding periplasmic protein CusF GbpA_2 PF18416.1 KFP16420.1 - 0.00022 21.5 1.0 26 5.2 0.0 6.0 6 0 0 6 6 6 0 N-acetylglucosamine binding protein domain 2 RsgA_N PF16745.5 KFP16420.1 - 0.0048 16.6 6.0 19 5.1 0.0 5.8 7 0 0 7 7 7 0 RsgA N-terminal domain DUF3857 PF12969.7 KFP16420.1 - 0.019 15.0 0.1 9.4 6.3 0.0 3.8 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3857) MazE_antitoxin PF04014.18 KFP16420.1 - 0.025 14.5 6.7 7.6 6.6 0.1 5.4 5 0 0 5 5 5 0 Antidote-toxin recognition MazE, bacterial antitoxin RlmM_FDX PF18125.1 KFP16420.1 - 0.35 11.4 2.1 52 4.4 0.0 3.8 4 0 0 4 4 4 0 RlmM ferredoxin-like domain OB_RNB PF08206.11 KFP16420.1 - 0.41 10.4 9.7 26 4.6 0.1 5.1 5 0 0 5 5 5 0 Ribonuclease B OB domain Ras PF00071.22 KFP16421.1 - 5.6e-43 146.4 0.1 6.3e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16421.1 - 2e-11 44.2 0.0 4e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP16421.1 - 2e-06 27.5 0.0 3.8e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFP16421.1 - 0.00015 21.3 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP16421.1 - 0.0063 16.4 0.0 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFP16421.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B TPP_enzyme_M PF00205.22 KFP16421.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain A_deaminase PF00962.22 KFP16422.1 - 9.7e-129 429.4 1.5 4.8e-128 427.1 1.5 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase DENN PF02141.21 KFP16423.1 - 9.4e-60 201.8 1.0 1.9e-59 200.8 1.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP16423.1 - 3.6e-15 56.4 0.6 8e-15 55.3 0.6 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP16423.1 - 9.2e-10 38.4 2.7 2.4e-09 37.0 2.7 1.8 1 0 0 1 1 1 1 dDENN domain DUF1744 PF08490.12 KFP16423.1 - 0.17 10.4 0.8 0.27 9.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) BCAS2 PF05700.11 KFP16424.1 - 1.3e-41 142.6 15.3 1.4e-41 142.4 15.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) EzrA PF06160.12 KFP16424.1 - 0.00035 18.9 7.7 0.00043 18.6 7.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA HAUS2 PF15003.6 KFP16424.1 - 0.0014 18.4 1.1 0.0019 17.9 0.7 1.5 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 2 DUF4201 PF13870.6 KFP16424.1 - 0.002 17.9 9.7 0.028 14.2 7.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Filament PF00038.21 KFP16424.1 - 0.0098 15.5 10.3 0.012 15.2 10.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein THOC7 PF05615.13 KFP16424.1 - 0.011 16.0 11.5 0.02 15.1 2.9 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 SCRG1 PF15224.6 KFP16424.1 - 0.014 15.5 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 Scrapie-responsive protein 1 Tup_N PF08581.10 KFP16424.1 - 0.028 14.7 10.9 0.16 12.2 2.8 2.5 1 1 1 2 2 2 0 Tup N-terminal CENP-F_leu_zip PF10473.9 KFP16424.1 - 0.034 14.2 10.6 0.061 13.4 10.6 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mesd PF10185.9 KFP16424.1 - 0.037 14.0 3.5 1 9.3 0.5 2.2 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor DUF2508 PF10704.9 KFP16424.1 - 0.041 14.0 0.5 0.041 14.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Phlebovirus_NSM PF07246.11 KFP16424.1 - 0.045 13.1 5.0 0.055 12.8 5.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OmpH PF03938.14 KFP16424.1 - 0.05 13.9 7.1 0.049 14.0 6.6 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 KFP16424.1 - 0.056 12.7 12.5 0.16 11.3 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 KFP16424.1 - 0.07 13.6 2.2 1.8 9.1 0.1 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.13 KFP16424.1 - 0.078 13.4 8.1 1.4 9.4 1.3 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TMCO5 PF14992.6 KFP16424.1 - 0.15 11.6 10.2 0.14 11.7 9.5 1.4 1 1 0 1 1 1 0 TMCO5 family bZIP_1 PF00170.21 KFP16424.1 - 0.2 11.8 5.5 6.3 7.0 0.1 2.7 2 1 0 2 2 2 0 bZIP transcription factor PRKG1_interact PF15898.5 KFP16424.1 - 0.21 12.5 10.5 0.09 13.7 6.4 2.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 KFP16424.1 - 0.22 11.9 9.1 0.52 10.7 7.0 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 KFP16424.1 - 0.25 11.1 8.0 0.6 9.9 8.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 KFP16424.1 - 0.47 10.6 11.2 1.6 8.9 2.0 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KFP16424.1 - 0.5 10.2 12.6 1 9.2 1.2 2.5 3 0 0 3 3 2 0 Septum formation initiator Ribosomal_L29 PF00831.23 KFP16424.1 - 0.58 10.2 7.4 1.1 9.3 1.9 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein KLRAQ PF10205.9 KFP16424.1 - 0.65 10.3 8.9 2.4 8.4 1.7 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 KFP16424.1 - 0.72 10.3 8.3 1.5 9.2 0.2 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GPS2_interact PF15784.5 KFP16424.1 - 0.84 10.1 8.4 2.6 8.5 1.3 2.4 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain GIT_CC PF16559.5 KFP16424.1 - 1.1 9.2 11.7 2.7 7.9 3.6 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1192 PF06698.11 KFP16424.1 - 1.1 9.4 4.4 2.1 8.4 0.4 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.7 KFP16424.1 - 1.2 9.2 11.6 0.27 11.4 2.6 2.3 1 1 1 2 2 2 0 Tropomyosin like Csm1_N PF18504.1 KFP16424.1 - 1.7 9.0 12.8 0.35 11.2 1.2 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KFP16424.1 - 1.9 8.6 13.2 0.5 10.4 8.9 2.2 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 KFP16424.1 - 2.5 8.4 11.5 3 8.1 2.1 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Med9 PF07544.13 KFP16424.1 - 3.4 7.8 9.6 4.8 7.4 0.6 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 KFP16424.1 - 5 7.4 12.0 9.5 6.6 3.2 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain Prefoldin PF02996.17 KFP16424.1 - 6.3 6.7 10.6 2.9 7.8 1.1 2.6 2 1 1 3 3 3 0 Prefoldin subunit TolA_bind_tri PF16331.5 KFP16424.1 - 8.2 6.6 12.4 4.1 7.5 5.5 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation MRPL52 PF18699.1 KFP16424.1 - 9.1 6.6 11.1 0.46 10.7 2.4 2.3 1 1 0 2 2 2 0 Mitoribosomal protein mL52 C2 PF00168.30 KFP16425.1 - 7.7e-55 183.5 0.0 3e-26 91.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain PI3K_C2 PF00792.24 KFP16425.1 - 0.00017 21.5 0.1 0.12 12.3 0.0 3.0 4 0 0 4 4 4 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFP16425.1 - 0.00041 20.0 0.0 0.057 13.0 0.0 2.7 3 0 0 3 3 3 2 CEP76 C2 domain DOCK-C2 PF14429.6 KFP16425.1 - 0.057 13.2 0.8 1.7 8.4 0.0 2.2 1 1 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins LapA_dom PF06305.11 KFP16425.1 - 0.41 10.5 1.4 0.96 9.3 1.4 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KFP16426.1 - 8.6e-51 172.8 0.0 1.5e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16426.1 - 3.3e-24 85.6 0.0 5.2e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP16426.1 - 1.3e-05 24.7 0.0 3.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP16426.1 - 0.0087 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP16426.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KFP16426.1 - 0.023 13.7 0.1 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.20 KFP16427.1 - 2.6e-33 115.4 0.0 2.9e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KFP16427.1 - 0.0014 19.0 0.2 0.83 10.1 0.0 3.6 2 1 2 4 4 4 1 HEAT repeats HEAT PF02985.22 KFP16427.1 - 0.0047 17.1 1.5 4.2 7.9 0.0 4.7 3 1 1 4 4 4 1 HEAT repeat Bcl-2 PF00452.19 KFP16428.1 - 0.038 14.7 0.1 0.063 14.0 0.1 1.4 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family TelA PF05816.11 KFP16428.1 - 0.07 12.2 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Phtf-FEM1B_bdg PF12129.8 KFP16429.1 - 8.5e-51 171.8 2.0 2.6e-50 170.2 2.0 1.9 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.24 KFP16430.1 - 1.5e-65 217.5 8.3 1e-15 57.8 0.6 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFP16430.1 - 2.6e-44 148.8 17.1 7.4e-12 44.9 0.8 5.6 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KFP16430.1 - 5.1e-25 87.6 0.1 0.00015 22.0 0.0 5.4 5 0 0 5 5 5 5 PDZ domain WW PF00397.26 KFP16430.1 - 2.2e-17 62.8 5.3 1.3e-08 34.8 0.1 2.6 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.21 KFP16430.1 - 2.8e-10 40.2 0.0 5.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFP16430.1 - 1.6e-05 24.7 6.3 0.26 11.3 0.1 4.9 5 0 0 5 5 5 2 Tricorn protease PDZ domain MAGI_u1 PF16663.5 KFP16430.1 - 1.7e-05 24.8 6.2 1.7e-05 24.8 6.2 2.4 2 0 0 2 2 2 1 Unstructured region on MAGI OB_RNB PF08206.11 KFP16430.1 - 0.067 12.9 1.1 49 3.7 0.0 4.1 4 0 0 4 4 4 0 Ribonuclease B OB domain MFS_1 PF07690.16 KFP16431.1 - 1e-37 129.9 35.4 5.2e-31 107.8 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Connexin PF00029.19 KFP16431.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Connexin TMEMspv1-c74-12 PF11044.8 KFP16431.1 - 0.68 10.0 0.1 0.68 10.0 0.1 2.8 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TAFA PF12020.8 KFP16432.1 - 3.4e-23 81.9 2.9 5.1e-23 81.3 2.9 1.2 1 0 0 1 1 1 1 TAFA family PP2C PF00481.21 KFP16433.1 - 1.9e-28 99.8 0.0 4.1e-13 49.6 0.0 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 KFP16433.1 - 1.7e-05 24.9 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ras PF00071.22 KFP16434.1 - 3.1e-58 196.0 0.0 3.5e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16434.1 - 2.5e-23 82.6 0.0 3.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16434.1 - 2.3e-10 40.2 0.0 4.1e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP16434.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP16434.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP16434.1 - 0.043 13.2 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_12 PF13087.6 KFP16435.1 - 3.3e-44 150.9 0.0 6.2e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP16435.1 - 4.9e-27 95.3 0.0 5.3e-13 49.3 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFP16435.1 - 1e-12 48.2 0.0 2.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP16435.1 - 2.8e-08 34.2 0.0 1.4e-07 31.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFP16435.1 - 2.2e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KFP16435.1 - 0.0026 17.6 0.0 0.01 15.7 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KFP16435.1 - 0.0078 16.6 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP16435.1 - 0.0089 16.3 0.0 0.029 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 KFP16435.1 - 0.025 13.8 0.0 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Herpes_pp85 PF04637.12 KFP16435.1 - 0.057 11.8 0.1 0.095 11.1 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AAA_16 PF13191.6 KFP16435.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain UvrD-helicase PF00580.21 KFP16435.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 KFP16435.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region F-actin_cap_A PF01267.17 KFP16436.1 - 1.3e-105 352.7 0.5 1.4e-105 352.5 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CCP_MauG PF03150.14 KFP16436.1 - 0.0098 16.5 0.1 0.31 11.7 0.1 2.4 1 1 2 3 3 3 1 Di-haem cytochrome c peroxidase ST7 PF04184.12 KFP16437.1 - 6.5e-286 949.0 1.5 7.3e-286 948.8 1.5 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KFP16437.1 - 0.0018 18.8 0.3 0.0089 16.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP16437.1 - 0.028 14.5 4.5 2 8.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP16437.1 - 0.033 14.0 4.4 11 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KFP16437.1 - 0.034 14.0 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_8 PF13181.6 KFP16437.1 - 0.16 12.3 1.8 21 5.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP16437.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP16437.1 - 2.7 9.0 11.9 18 6.5 0.7 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat wnt PF00110.19 KFP16438.1 - 4.7e-124 414.0 28.9 5.3e-124 413.8 28.9 1.0 1 0 0 1 1 1 1 wnt family CortBP2 PF09727.9 KFP16439.1 - 2.3e-68 229.9 19.8 2.3e-68 229.9 19.8 2.5 2 0 0 2 2 2 1 Cortactin-binding protein-2 DUF3037 PF11236.8 KFP16439.1 - 0.91 10.0 12.7 0.29 11.6 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) DUF812 PF05667.11 KFP16439.1 - 0.97 8.2 31.9 2.1 7.2 31.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) hDGE_amylase PF14701.6 KFP16439.1 - 3.2 6.8 11.4 6 5.8 11.4 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Rootletin PF15035.6 KFP16439.1 - 4 7.4 37.0 5 7.1 14.2 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion BTB_2 PF02214.22 KFP16440.1 - 2e-29 101.8 0.1 4.2e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KFP16440.1 - 5.8e-29 101.0 14.0 1e-28 100.3 14.0 1.4 1 0 0 1 1 1 1 Ion transport protein BTB_3 PF16017.5 KFP16440.1 - 2e-05 24.7 0.0 5.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 KFP16440.1 - 0.095 11.4 10.9 0.044 12.5 8.5 1.5 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans_2 PF07885.16 KFP16440.1 - 1.2 9.2 14.7 0.055 13.4 4.3 2.8 3 0 0 3 3 3 0 Ion channel DUF3399 PF11879.8 KFP16441.1 - 1.4e-46 157.0 11.1 1.4e-46 157.0 11.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans PF00520.31 KFP16441.1 - 0.00077 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP16441.1 - 0.0015 18.5 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 Ion channel DUF702 PF05142.12 KFP16441.1 - 0.023 15.2 0.8 0.051 14.1 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Helicase_C PF00271.31 KFP16442.1 - 4e-25 88.3 0.1 1.7e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP16442.1 - 4.7e-22 78.6 0.0 1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 KFP16442.1 - 0.22 10.8 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ras PF00071.22 KFP16443.1 - 4.2e-53 179.3 0.3 4.7e-53 179.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16443.1 - 6.5e-21 74.8 0.0 9.7e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16443.1 - 4.7e-09 35.9 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP16443.1 - 5.6e-05 22.8 0.2 0.00012 21.7 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP16443.1 - 0.00051 20.1 0.0 0.00069 19.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFP16443.1 - 0.0011 18.3 0.0 0.0071 15.5 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KFP16443.1 - 0.0028 17.6 2.6 1.1 9.1 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase Mt_ATP-synt_B PF05405.14 KFP16444.1 - 3.9e-51 172.9 8.9 4.4e-51 172.8 8.9 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ureide_permease PF07168.11 KFP16444.1 - 0.09 11.5 0.8 0.11 11.3 0.1 1.4 1 1 1 2 2 2 0 Ureide permease ANAPC4_WD40 PF12894.7 KFP16445.1 - 1.1e-06 28.8 0.1 0.35 11.2 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP16445.1 - 7.3e-06 26.6 17.0 0.00012 22.8 0.3 4.7 5 1 1 6 6 6 2 WD domain, G-beta repeat TFIIIC_delta PF12657.7 KFP16445.1 - 0.0029 17.6 0.2 0.012 15.5 0.2 1.8 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term EF-hand_1 PF00036.32 KFP16447.1 - 1.3e-22 77.6 11.6 7.2e-07 28.3 0.2 4.8 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.6 KFP16447.1 - 4.3e-21 75.1 3.7 5.2e-14 52.5 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP16447.1 - 1.4e-20 71.3 5.8 1.9e-05 24.2 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KFP16447.1 - 1.2e-17 63.4 2.8 1.9e-08 34.0 0.6 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP16447.1 - 2.3e-14 52.1 9.1 8.5e-06 25.0 0.9 4.2 4 1 1 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 KFP16447.1 - 3e-07 30.8 0.4 0.00043 20.6 0.1 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP16447.1 - 7.8e-06 25.8 2.8 0.26 11.3 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP16447.1 - 6e-05 23.2 0.5 0.018 15.2 0.3 2.7 2 1 0 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 KFP16447.1 - 0.017 15.1 0.6 8.8 6.2 0.0 2.9 1 1 2 3 3 3 0 Caleosin related protein DUF4891 PF16232.5 KFP16447.1 - 0.048 14.2 0.0 3.4 8.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4891) EF-hand_10 PF14788.6 KFP16447.1 - 0.059 13.2 1.1 2.2 8.2 0.2 2.3 2 0 0 2 2 2 0 EF hand VCBS PF13517.6 KFP16447.1 - 0.063 13.9 2.5 8.1 7.1 0.1 3.0 2 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella adh_short PF00106.25 KFP16448.1 - 2.6e-43 147.8 0.1 3.3e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP16448.1 - 2e-23 83.2 0.0 2.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP16448.1 - 1.6e-07 31.4 0.4 0.0048 16.8 0.2 2.1 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 KFP16448.1 - 1.1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KFP16448.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 KFP16449.1 - 2.2e-43 148.0 0.1 2.6e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP16449.1 - 1.5e-21 77.1 0.0 1.6e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP16449.1 - 6.5e-08 32.7 1.1 0.0012 18.8 0.5 2.1 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 KFP16449.1 - 0.0022 17.4 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 KFP16449.1 - 0.095 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 KFP16449.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KFP16449.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KFP16449.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain G0-G1_switch_2 PF15103.6 KFP16450.1 - 4.8e-43 145.9 0.6 5.4e-43 145.7 0.6 1.0 1 0 0 1 1 1 1 G0/G1 switch protein 2 Pkinase PF00069.25 KFP16451.1 - 3.8e-77 259.2 0.2 5.7e-77 258.6 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16451.1 - 4e-33 114.8 0.0 5.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP16451.1 - 7.9e-10 38.5 0.0 1.3e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP16451.1 - 5.4e-05 22.6 0.0 9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP16451.1 - 0.00039 19.3 0.0 0.001 17.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KFP16451.1 - 0.00056 19.5 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP16451.1 - 0.005 16.8 0.0 0.12 12.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CsgA PF17334.2 KFP16451.1 - 0.019 15.7 0.9 0.26 12.0 0.0 2.7 3 0 0 3 3 3 0 Minor curli fiber component A YrbL-PhoP_reg PF10707.9 KFP16451.1 - 0.1 12.1 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL hSac2 PF12456.8 KFP16452.1 - 1.6e-18 66.5 0.0 3.6e-18 65.3 0.0 1.5 2 0 0 2 2 2 1 Inositol phosphatase ANAPC4_WD40 PF12894.7 KFP16453.1 - 6.6e-12 45.6 0.9 0.003 17.8 0.0 6.8 2 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP16453.1 - 1.8e-09 38.0 5.1 0.012 16.5 0.0 7.7 7 1 1 8 8 8 2 WD domain, G-beta repeat eIF2A PF08662.11 KFP16453.1 - 4.9e-08 33.1 0.1 0.18 11.7 0.0 4.1 2 2 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KFP16453.1 - 0.041 13.8 0.7 38 4.4 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KFP16453.1 - 0.054 11.5 4.5 1.2 7.0 0.1 3.0 2 1 2 5 5 5 0 IKI3 family ATG16 PF08614.11 KFP16454.1 - 0.014 15.6 18.8 0.014 15.6 18.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MPS2 PF17060.5 KFP16454.1 - 0.058 12.7 16.3 0.048 12.9 15.1 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 MAD PF05557.13 KFP16454.1 - 0.16 10.3 29.8 0.48 8.7 28.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Phage_GP20 PF06810.11 KFP16454.1 - 0.23 11.2 11.7 0.15 11.8 1.0 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 STATa_Ig PF18214.1 KFP16454.1 - 0.32 11.0 4.9 0.1 12.6 0.7 2.3 1 1 0 2 2 2 0 STATa Immunoglobulin-like domain Spc7 PF08317.11 KFP16454.1 - 0.48 9.2 26.8 1 8.1 26.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein RRT14 PF17075.5 KFP16454.1 - 0.64 10.1 18.5 0.35 11.0 16.1 1.7 1 1 1 2 2 2 0 Regular of rDNA transcription protein 14 Atg14 PF10186.9 KFP16454.1 - 1.2 8.2 18.9 1.6 7.7 18.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 KFP16454.1 - 1.8 8.6 20.9 1.6 8.8 4.3 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SOGA PF11365.8 KFP16454.1 - 2.6 9.2 20.4 1 10.5 14.4 2.5 2 1 1 3 3 3 0 Protein SOGA Fez1 PF06818.15 KFP16454.1 - 3.8 7.9 26.9 11 6.4 24.1 2.0 1 1 1 2 2 2 0 Fez1 Uso1_p115_C PF04871.13 KFP16454.1 - 4.1 7.8 23.3 2.9 8.3 10.9 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Peptidase_S46 PF10459.9 KFP16454.1 - 8.5 4.9 16.3 11 4.5 16.3 1.0 1 0 0 1 1 1 0 Peptidase S46 B3_4 PF03483.17 KFP16455.1 - 5.4e-11 42.5 0.0 9.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain SpoVG PF04026.12 KFP16455.1 - 0.0046 17.1 0.1 8.5 6.7 0.0 3.2 3 0 0 3 3 3 2 SpoVG LRR_4 PF12799.7 KFP16455.1 - 0.041 14.3 0.1 0.26 11.8 0.0 2.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) UVR PF02151.19 KFP16456.1 - 0.0014 18.3 13.9 0.071 12.9 3.2 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif CLASP_N PF12348.8 KFP16456.1 - 0.012 15.2 0.2 0.027 14.0 0.2 1.6 1 0 0 1 1 1 0 CLASP N terminal zf_UBZ PF18439.1 KFP16456.1 - 0.014 14.9 8.2 0.5 10.0 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KFP16456.1 - 0.038 14.1 0.8 4.2 7.5 0.1 2.8 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Pkinase_C PF00433.24 KFP16456.1 - 0.15 12.7 0.1 0.78 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein kinase C terminal domain DFF40 PF09230.10 KFP16457.1 - 2.6e-89 298.7 3.4 2.9e-89 298.6 3.4 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa UPF0688 PF15772.5 KFP16458.1 - 1.3e-55 189.2 9.7 1.7e-55 188.8 9.7 1.1 1 0 0 1 1 1 1 UPF0688 family Keratin PF02422.16 KFP16460.1 - 3.2e-36 122.9 14.9 3.5e-36 122.8 14.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP16462.1 - 6.3e-34 115.6 12.2 6.8e-34 115.5 12.2 1.0 1 0 0 1 1 1 1 Keratin 7tm_4 PF13853.6 KFP16463.1 - 6.7e-38 131.0 4.3 8e-38 130.8 4.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16463.1 - 4.1e-29 101.7 3.7 6e-29 101.2 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16463.1 - 4.4e-05 23.0 7.3 6.7e-05 22.4 7.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP16463.1 - 0.00016 21.1 5.0 0.0004 19.9 5.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP16463.1 - 0.0094 15.6 5.2 0.018 14.7 5.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx MHC_I PF00129.18 KFP16464.1 - 1.1e-33 116.3 0.9 1.4e-33 115.9 0.9 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 C1-set PF07654.15 KFP16464.1 - 8.5e-17 61.3 0.0 1.8e-16 60.3 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.6 KFP16464.1 - 1.1e-07 32.3 0.1 2.5e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin domain MHC_I_3 PF16497.5 KFP16464.1 - 1.4e-05 24.6 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 MHC-I family domain Ig_2 PF13895.6 KFP16464.1 - 0.00039 20.7 0.0 0.00066 20.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP16464.1 - 0.0017 18.5 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP16464.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 KFP16464.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP16465.1 - 1.1e-19 70.6 0.0 1.7e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin C1-set domain MHC_II_beta PF00969.19 KFP16465.1 - 3.1e-07 30.4 0.1 4.2e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Class II histocompatibility antigen, beta domain Ig_3 PF13927.6 KFP16465.1 - 8e-05 23.2 0.1 0.00014 22.4 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP16465.1 - 0.0011 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP16465.1 - 0.003 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 KFP16465.1 - 0.0098 15.9 0.1 0.037 14.1 0.1 1.9 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain TLV_coat PF00429.19 KFP16466.1 - 2.7e-05 23.1 0.4 2.8e-05 23.0 0.4 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Cadherin PF00028.17 KFP16467.1 - 5e-63 209.6 0.8 2.6e-16 59.8 0.0 5.7 6 0 0 6 6 6 5 Cadherin domain Cadherin_pro PF08758.11 KFP16467.1 - 6.2e-19 68.0 3.6 1.9e-17 63.2 0.4 3.6 4 0 0 4 4 4 1 Cadherin prodomain like Cadherin_C PF01049.17 KFP16467.1 - 1.8e-07 31.6 0.0 4.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP16467.1 - 1.9e-05 24.4 0.0 0.016 15.0 0.0 3.6 4 0 0 4 4 4 2 Cadherin-like Cadherin PF00028.17 KFP16468.1 - 3.2e-52 174.9 0.0 6.7e-16 58.5 0.0 4.5 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.17 KFP16468.1 - 2e-06 28.2 0.0 3.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP16468.1 - 0.00043 20.1 0.0 6.2 6.7 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like RET_CLD1 PF17756.1 KFP16468.1 - 0.019 15.3 0.0 0.37 11.1 0.0 2.5 2 0 0 2 2 2 0 RET Cadherin like domain 1 Cadherin PF00028.17 KFP16469.1 - 8.8e-59 196.0 4.8 2e-20 73.0 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 KFP16469.1 - 1.9e-07 30.8 0.1 0.091 12.6 0.0 4.5 3 1 1 4 4 4 3 Cadherin-like Cadherin_C PF01049.17 KFP16469.1 - 0.00028 21.2 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region SEC-C PF02810.15 KFP16469.1 - 0.58 10.1 2.7 1.7 8.7 2.7 1.8 1 0 0 1 1 1 0 SEC-C motif Transthyretin PF00576.21 KFP16470.1 - 3.4e-21 76.0 0.1 4.3e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Lipase_C PF18067.1 KFP16470.1 - 0.13 12.9 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase C-terminal domain Transthyretin PF00576.21 KFP16471.1 - 3.8e-22 79.1 0.0 4.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family TTR-52 PF01060.23 KFP16471.1 - 0.043 14.5 0.0 0.064 14.0 0.0 1.2 1 0 0 1 1 1 0 Transthyretin-like family Glyco_transf_7N PF13733.6 KFP16472.1 - 6.3e-55 184.5 0.0 1e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP16472.1 - 3.8e-28 97.0 0.7 6.8e-28 96.1 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ribosomal_S21e PF01249.18 KFP16473.1 - 3.2e-22 78.4 0.1 3.4e-22 78.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Astacin PF01400.24 KFP16474.1 - 8.4e-72 240.8 0.2 1.9e-71 239.7 0.1 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) MAM PF00629.23 KFP16474.1 - 6.7e-42 143.1 0.1 2.8e-40 137.9 0.1 2.3 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu EGF PF00008.27 KFP16474.1 - 3e-05 24.2 3.0 8.1e-05 22.8 3.0 1.8 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP16474.1 - 0.0043 17.6 4.3 0.016 15.8 4.3 2.1 1 0 0 1 1 1 1 Human growth factor-like EGF SSP160 PF06933.11 KFP16474.1 - 0.55 8.4 10.5 0.82 7.8 10.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EGF_2 PF07974.13 KFP16474.1 - 2.3 8.6 5.3 7.3 7.1 5.3 1.9 1 0 0 1 1 1 0 EGF-like domain CABIT PF12736.7 KFP16475.1 - 9.9e-55 185.8 0.7 1.6e-54 185.2 0.7 1.3 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.30 KFP16475.1 - 0.0027 18.1 0.1 0.0049 17.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras PF00071.22 KFP16476.1 - 1.2e-44 151.8 0.0 1.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16476.1 - 3.6e-20 72.4 0.1 5.3e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16476.1 - 6.5e-09 35.5 0.1 7.9e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP16476.1 - 0.00021 20.9 0.0 0.00036 20.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP16476.1 - 0.0056 16.1 0.1 0.0087 15.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TSNAXIP1_N PF15739.5 KFP16477.1 - 0.092 13.1 0.8 0.092 13.1 0.8 2.5 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus SNX17_FERM_C PF18116.1 KFP16477.1 - 0.11 12.6 3.2 0.079 13.1 1.0 1.8 1 1 1 2 2 2 0 Sorting Nexin 17 FERM C-terminal domain ASXH PF13919.6 KFP16478.1 - 8.4e-35 119.8 1.8 1.6e-34 118.9 0.2 2.4 2 0 0 2 2 2 1 Asx homology domain PHD_3 PF13922.6 KFP16478.1 - 1.6e-20 73.2 8.2 1.6e-20 73.2 8.2 2.9 2 0 0 2 2 2 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.13 KFP16478.1 - 0.00023 21.5 0.0 0.00054 20.3 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain DUF1284 PF06935.11 KFP16478.1 - 0.085 13.3 3.7 0.068 13.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) PRIMA1 PF16101.5 KFP16478.1 - 0.59 10.2 8.0 3 7.9 8.0 2.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Integrase_H2C2 PF17921.1 KFP16479.1 - 0.00019 21.5 3.5 0.0011 19.0 0.2 2.5 2 1 0 2 2 2 1 Integrase zinc binding domain BEN PF10523.9 KFP16479.1 - 0.008 16.4 0.3 0.29 11.4 0.0 2.8 2 0 0 2 2 2 1 BEN domain EF-hand_2 PF09068.11 KFP16480.1 - 9.7e-35 119.4 1.5 3e-34 117.8 0.7 2.2 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.11 KFP16480.1 - 3e-30 104.5 0.1 1.6e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand ZZ PF00569.17 KFP16480.1 - 2.9e-09 36.6 9.7 2.9e-09 36.6 9.7 1.6 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 KFP16480.1 - 0.0017 18.6 7.4 0.0036 17.6 7.4 1.5 1 0 0 1 1 1 1 C1 domain Seryl_tRNA_N PF02403.22 KFP16480.1 - 0.016 15.4 7.9 0.069 13.4 7.9 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KFP16480.1 - 0.39 11.9 11.5 0.17 13.0 7.7 2.5 2 1 0 2 2 2 0 Protein SOGA FapA PF03961.13 KFP16480.1 - 0.49 8.9 5.8 0.88 8.1 5.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MerR-DNA-bind PF09278.11 KFP16480.1 - 2.2 8.9 11.9 3 8.5 10.1 2.2 1 1 1 2 2 2 0 MerR, DNA binding CEBP_ZZ PF16366.5 KFP16480.1 - 3.7 7.9 12.2 7.9 6.8 12.2 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RVT_1 PF00078.27 KFP16481.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EB1 PF03271.17 KFP16482.1 - 4e-16 59.0 0.5 1.2e-15 57.4 0.3 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFP16482.1 - 3.5e-13 49.7 0.3 6e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP16482.1 - 0.0014 18.4 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain MIS13 PF08202.11 KFP16482.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family CDP-OH_P_transf PF01066.21 KFP16483.1 - 5.5e-16 59.1 0.3 5.5e-16 59.1 0.3 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4502 PF14950.6 KFP16484.1 - 2.7e-40 139.0 19.5 3e-40 138.9 19.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) DUF4503 PF14951.6 KFP16485.1 - 4.7e-170 565.3 8.4 4.7e-170 565.3 8.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) DUF4502 PF14950.6 KFP16485.1 - 2.3e-52 178.7 0.5 3.5e-52 178.1 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) PI3_PI4_kinase PF00454.27 KFP16486.1 - 2.1e-18 67.0 0.1 2.6e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase fn3 PF00041.21 KFP16487.1 - 1.6e-38 130.9 12.0 6.2e-15 55.3 0.1 4.3 4 0 0 4 4 4 3 Fibronectin type III domain Cys_box PF17869.1 KFP16487.1 - 5.8e-27 93.6 11.5 5.8e-27 93.6 11.5 2.4 2 0 0 2 2 2 1 Anosmin cysteine rich domain WAP PF00095.21 KFP16487.1 - 9.3e-10 38.7 15.4 9.3e-10 38.7 15.4 2.6 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.10 KFP16487.1 - 5.1e-05 23.5 2.8 0.0059 16.9 0.1 3.2 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFP16487.1 - 0.0031 18.0 5.6 0.33 11.6 0.5 4.1 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFP16487.1 - 0.025 14.9 0.1 1.3 9.5 0.1 3.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) DUF4959 PF16323.5 KFP16487.1 - 0.067 13.5 0.0 0.23 11.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4959) EF-hand_1 PF00036.32 KFP16488.1 - 2.1e-10 39.4 8.8 4.5e-06 25.8 0.9 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFP16488.1 - 2e-09 37.8 1.1 2e-09 37.8 1.1 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP16488.1 - 3.2e-09 36.0 2.2 1e-05 25.1 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KFP16488.1 - 1.2e-06 27.7 2.4 0.029 13.9 0.7 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KFP16488.1 - 6.3e-06 25.9 7.3 0.0099 15.7 0.5 2.6 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP16488.1 - 0.027 14.8 0.4 0.096 13.0 0.0 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GYF PF02213.16 KFP16489.1 - 1.4e-21 75.8 0.7 3.2e-21 74.7 0.7 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KFP16489.1 - 2.1e-06 27.5 0.1 8.1e-06 25.6 0.1 2.1 1 0 0 1 1 1 1 GYF domain 2 IRK PF01007.20 KFP16490.1 - 1.5e-46 157.8 0.1 2.4e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 KFP16490.1 - 3.8e-36 124.3 0.0 4.9e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 KFP16490.1 - 0.00015 21.6 3.3 0.00032 20.6 3.3 1.6 1 1 0 1 1 1 1 Ion channel DUF4690 PF15756.5 KFP16491.1 - 2.5e-46 156.2 0.2 2.8e-46 156.1 0.2 1.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage RhoGEF PF00621.20 KFP16492.1 - 1.7e-34 119.6 8.9 2.9e-34 118.9 8.9 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 KFP16492.1 - 2.3e-12 46.3 0.0 6.5e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP16492.1 - 2.5e-12 46.5 0.1 5.1e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP16492.1 - 3e-07 30.0 0.0 7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP16492.1 - 7.4e-06 26.4 0.3 8.8e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 PH domain SesA PF17107.5 KFP16492.1 - 0.012 15.8 0.6 0.044 14.0 0.6 1.9 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SH3_16 PF18348.1 KFP16492.1 - 0.041 13.7 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain BNR_2 PF13088.6 KFP16493.1 - 7.9e-38 130.3 0.0 1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFP16493.1 - 0.00082 19.0 5.0 0.18 11.9 0.1 3.6 4 0 0 4 4 4 2 BNR/Asp-box repeat ATG16 PF08614.11 KFP16494.1 - 1.5e-37 129.8 29.0 1.5e-37 129.8 29.0 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 KFP16494.1 - 4.2e-35 119.2 12.1 1.1e-06 29.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16494.1 - 6.6e-10 39.2 0.2 0.0034 17.6 0.0 4.8 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP16494.1 - 1.6e-06 28.1 0.0 0.14 12.1 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A ERM PF00769.19 KFP16494.1 - 5.3e-06 26.4 19.5 9.6e-06 25.6 19.5 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Ge1_WD40 PF16529.5 KFP16494.1 - 1.7e-05 24.0 0.2 0.39 9.6 0.2 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP16494.1 - 6.5e-05 21.8 7.3 1.5 7.4 0.0 4.6 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Fez1 PF06818.15 KFP16494.1 - 0.0044 17.5 26.4 0.0074 16.8 26.4 1.3 1 0 0 1 1 1 1 Fez1 ZapB PF06005.12 KFP16494.1 - 0.0061 17.0 7.9 0.0061 17.0 7.9 3.7 1 1 2 3 3 2 1 Cell division protein ZapB KASH_CCD PF14662.6 KFP16494.1 - 0.01 15.7 12.4 0.01 15.7 12.4 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 KFP16494.1 - 0.02 12.9 11.1 0.025 12.5 11.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_6 PF01418.17 KFP16494.1 - 0.056 13.4 1.0 0.16 12.0 1.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family SGL PF08450.12 KFP16494.1 - 0.068 12.8 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region WD40_like PF17005.5 KFP16494.1 - 0.069 12.5 0.0 0.52 9.6 0.0 2.4 3 1 0 3 3 3 0 WD40-like domain Lipoprotein_6 PF01441.19 KFP16494.1 - 0.072 13.1 4.9 0.12 12.3 4.5 1.6 1 1 0 1 1 1 0 Lipoprotein Peptidase_M15_4 PF13539.6 KFP16494.1 - 0.13 12.8 0.0 0.46 11.0 0.0 1.9 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase YabA PF06156.13 KFP16494.1 - 0.33 11.6 20.6 0.18 12.4 7.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA YicC_N PF03755.13 KFP16494.1 - 0.53 10.7 9.0 1.1 9.8 9.0 1.5 1 0 0 1 1 1 0 YicC-like family, N-terminal region NPV_P10 PF05531.12 KFP16494.1 - 1.3 9.6 4.9 0.76 10.3 0.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KFP16494.1 - 1.4 7.4 11.2 1.9 6.9 11.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MRP-S27 PF10037.9 KFP16494.1 - 1.5 7.6 18.0 2.3 7.0 18.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Lebercilin PF15619.6 KFP16494.1 - 1.8 8.2 34.8 3.1 7.4 34.8 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Synaptobrevin PF00957.21 KFP16494.1 - 1.9 8.3 6.4 2.9 7.7 4.9 2.1 2 0 0 2 2 2 0 Synaptobrevin Atg14 PF10186.9 KFP16494.1 - 2.4 7.2 16.1 4.6 6.2 16.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KFP16494.1 - 2.5 8.2 8.0 13 5.8 7.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 KFP16494.1 - 2.7 7.5 16.9 2.1 7.9 14.2 2.1 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase FlaC_arch PF05377.11 KFP16494.1 - 2.7 8.4 8.2 0.23 11.9 1.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 KFP16494.1 - 2.9 7.3 8.3 3.7 7.0 7.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF812 PF05667.11 KFP16494.1 - 2.9 6.7 27.3 4.3 6.1 27.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TSC22 PF01166.18 KFP16494.1 - 4.6 7.6 9.1 1.4 9.3 1.8 3.0 1 1 3 4 4 3 0 TSC-22/dip/bun family APG6_N PF17675.1 KFP16494.1 - 6.4 7.3 40.3 8.4 6.9 8.0 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 KFP16494.1 - 6.4 6.7 11.7 0.29 11.0 2.1 3.2 2 1 1 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 KFP16494.1 - 8 6.2 21.4 0.19 11.6 13.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 KFP16494.1 - 8.4 7.0 17.1 4.8 7.8 8.6 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal HALZ PF02183.18 KFP16494.1 - 8.6 6.7 13.2 0.35 11.1 5.0 3.1 2 2 2 4 4 2 0 Homeobox associated leucine zipper Arrestin_N PF00339.29 KFP16495.1 - 2e-38 131.7 0.2 2.9e-34 118.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFP16495.1 - 2e-26 93.0 1.7 3e-26 92.4 1.7 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Transglut_C PF00927.22 KFP16495.1 - 0.025 14.7 0.4 0.061 13.5 0.4 1.6 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF2079 PF09852.9 KFP16495.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DAGK_acc PF00609.19 KFP16496.1 - 2e-51 174.5 0.0 4.7e-51 173.3 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP16496.1 - 2.1e-27 95.3 0.1 5.5e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain SAM_2 PF07647.17 KFP16496.1 - 3e-19 68.9 1.0 1.5e-18 66.7 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) C1_1 PF00130.22 KFP16496.1 - 2.6e-18 65.6 28.9 1.9e-10 40.5 5.6 2.9 3 0 0 3 3 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_1 PF00536.30 KFP16496.1 - 1.6e-17 63.7 2.6 9.1e-17 61.3 0.6 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFP16496.1 - 2.9e-15 56.7 1.3 6.7e-15 55.5 0.2 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFP16496.1 - 0.00011 22.5 0.2 0.00025 21.3 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP16496.1 - 0.00011 22.5 2.5 0.0028 18.0 2.5 3.3 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 KFP16496.1 - 0.0018 18.5 16.0 0.014 15.7 5.7 3.0 2 0 0 2 2 2 2 C1 domain DUF2935 PF11155.8 KFP16496.1 - 0.004 17.5 0.0 0.48 10.8 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF2935) Mcp5_PH PF12814.7 KFP16496.1 - 0.009 16.1 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Med26 PF08711.11 KFP16497.1 - 1.2e-14 54.0 0.2 4.6e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LIM PF00412.22 KFP16498.1 - 8.6e-62 205.2 59.6 1.5e-14 54.0 3.2 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.21 KFP16499.1 - 1.9e-49 168.3 18.0 3.2e-49 167.6 18.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16499.1 - 7.2e-06 25.6 18.5 8.6e-06 25.3 18.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP16499.1 - 1.3e-05 24.7 11.8 2e-05 24.1 11.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 KFP16499.1 - 0.013 15.2 18.2 0.016 14.9 17.8 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor 7tm_4 PF13853.6 KFP16499.1 - 0.03 14.1 16.6 1 9.0 16.6 2.5 1 1 0 1 1 1 0 Olfactory receptor DUF5409 PF17421.2 KFP16499.1 - 0.046 14.4 0.4 0.046 14.4 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5409) 7TM_GPCR_Srx PF10328.9 KFP16499.1 - 0.067 12.8 22.2 0.009 15.7 10.2 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF983 PF06170.12 KFP16499.1 - 0.38 11.2 0.1 0.38 11.2 0.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF983) TauE PF01925.19 KFP16499.1 - 0.43 10.2 6.8 0.81 9.3 6.8 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF373 PF04123.13 KFP16499.1 - 0.87 9.0 5.3 1.4 8.3 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) WD40 PF00400.32 KFP16500.1 - 5.7e-32 109.3 14.5 1.9e-06 28.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16500.1 - 3.4e-11 43.3 1.8 0.57 10.5 0.0 5.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Collagen PF01391.18 KFP16500.1 - 2.3e-07 30.5 100.3 0.00027 20.6 26.8 9.9 6 1 3 9 9 9 3 Collagen triple helix repeat (20 copies) eIF2A PF08662.11 KFP16500.1 - 1.1e-05 25.4 3.4 0.042 13.7 0.7 2.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP16500.1 - 0.00067 18.7 0.0 0.012 14.6 0.1 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3292 PF11696.8 KFP16500.1 - 3 6.1 5.1 4.4 5.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RNA_pol_Rpb4 PF03874.16 KFP16501.1 - 1.1e-26 93.5 5.9 1.3e-26 93.3 5.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.16 KFP16501.1 - 0.0082 16.0 0.8 0.015 15.1 0.2 1.8 2 0 0 2 2 2 1 Rop protein AMMECR1 PF01871.17 KFP16502.1 - 1e-47 161.8 0.0 1.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Glyco_transf_24 PF18404.1 KFP16504.1 - 6.2e-148 491.4 5.7 6.8e-148 491.3 4.1 1.9 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_15 PF18403.1 KFP16504.1 - 4.3e-72 242.5 3.5 3.6e-65 219.9 0.7 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_14 PF18402.1 KFP16504.1 - 5.3e-67 226.5 11.0 1.5e-63 215.2 1.4 3.7 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFP16504.1 - 1.6e-54 184.7 0.5 1.1e-52 178.6 0.5 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFP16504.1 - 5.1e-40 136.0 0.0 1.5e-39 134.5 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KFP16504.1 - 7.4e-38 129.5 2.1 3.2e-37 127.5 0.3 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KFP16504.1 - 0.00023 20.8 0.4 0.00023 20.8 0.4 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 8 Sulfotransfer_2 PF03567.14 KFP16505.1 - 2e-48 165.5 0.5 3e-48 164.9 0.5 1.3 1 0 0 1 1 1 1 Sulfotransferase family NuA4 PF09340.10 KFP16505.1 - 0.53 10.2 2.7 1.2 9.0 2.7 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 F5_F8_type_C PF00754.25 KFP16506.1 - 6.4e-16 58.6 0.8 6.9e-16 58.5 0.8 1.0 1 0 0 1 1 1 1 F5/8 type C domain TLV_coat PF00429.19 KFP16507.1 - 0.00032 19.5 0.8 0.00034 19.5 0.8 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) MFS_1 PF07690.16 KFP16513.1 - 3.1e-34 118.5 39.6 4.1e-34 118.1 39.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP16513.1 - 5.3e-11 42.0 22.5 2.9e-09 36.3 22.5 2.5 1 1 0 1 1 1 1 MFS_1 like family Spin-Ssty PF02513.17 KFP16515.1 - 1.2e-76 252.3 7.8 6.5e-28 96.2 0.2 3.2 3 0 0 3 3 3 3 Spin/Ssty Family Thioredoxin_8 PF13905.6 KFP16516.1 - 4.1e-26 91.2 0.0 5.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KFP16516.1 - 1.6e-07 31.3 0.1 0.00032 20.7 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 KFP16516.1 - 3.7e-05 23.5 0.0 7.7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFP16516.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 KFP16516.1 - 0.036 14.5 0.0 0.063 13.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain CKS PF01111.19 KFP16518.1 - 6.4e-28 96.8 2.2 7.1e-28 96.7 2.2 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_L7Ae PF01248.26 KFP16519.1 - 9.7e-22 76.5 0.4 2e-21 75.5 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family tRNA_Me_trans PF03054.16 KFP16520.1 - 0.046 12.5 0.0 0.054 12.3 0.0 1.0 1 0 0 1 1 1 0 tRNA methyl transferase AEP1 PF17049.5 KFP16520.1 - 0.062 12.4 0.3 0.07 12.2 0.3 1.0 1 0 0 1 1 1 0 ATPase expression protein 1 Sema PF01403.19 KFP16521.1 - 6.1e-159 529.4 0.0 1e-158 528.7 0.0 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP16521.1 - 2.2e-07 31.3 4.6 7.6e-07 29.6 4.6 2.1 1 0 0 1 1 1 1 Plexin repeat ig PF00047.25 KFP16521.1 - 9.3e-07 28.9 0.1 3.8e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP16521.1 - 0.00022 21.5 0.0 0.00084 19.6 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 KFP16521.1 - 0.00035 20.9 2.7 0.00068 20.0 0.1 2.7 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFP16521.1 - 0.00048 20.7 0.0 0.0014 19.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP16521.1 - 0.00091 19.2 0.4 0.0024 17.9 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF3891 PF13030.6 KFP16521.1 - 0.0034 17.2 0.2 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3891) Pkinase_fungal PF17667.1 KFP16521.1 - 0.13 11.0 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PSI_integrin PF17205.3 KFP16521.1 - 0.4 10.5 3.3 0.6 9.9 1.5 2.3 2 0 0 2 2 2 0 Integrin plexin domain Ras PF00071.22 KFP16527.1 - 1.3e-50 171.2 0.1 1.6e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16527.1 - 1.8e-17 63.7 0.0 3.7e-17 62.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16527.1 - 5e-07 29.3 0.0 7.1e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP16527.1 - 0.00026 21.1 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP16527.1 - 0.00062 19.7 2.1 0.42 10.5 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFP16527.1 - 0.0037 16.7 0.8 0.014 14.8 0.8 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KFP16527.1 - 0.0041 16.1 0.6 0.32 9.9 0.3 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFP16527.1 - 0.026 14.9 0.1 0.041 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFP16527.1 - 0.046 13.4 0.5 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2408 PF10303.9 KFP16527.1 - 0.074 13.6 5.3 0.87 10.1 5.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) AAA_22 PF13401.6 KFP16527.1 - 0.091 13.0 0.2 0.36 11.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP16527.1 - 0.15 12.3 0.1 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain p25-alpha PF05517.12 KFP16528.1 - 4.1e-50 170.0 3.8 1.8e-37 128.9 0.7 2.0 2 0 0 2 2 2 2 p25-alpha EF-hand_7 PF13499.6 KFP16528.1 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP16528.1 - 0.27 11.1 1.4 1.8 8.5 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KFP16528.1 - 0.51 10.0 3.5 0.75 9.5 0.0 2.9 4 0 0 4 4 4 0 EF hand ECH_1 PF00378.20 KFP16529.1 - 9.2e-59 198.8 0.1 1e-58 198.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP16529.1 - 2e-30 106.5 0.2 1.6e-29 103.5 0.2 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Vert_IL3-reg_TF PF06529.11 KFP16531.1 - 3.9e-186 617.9 21.3 5.8e-186 617.3 21.3 1.3 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor bZIP_2 PF07716.15 KFP16531.1 - 1.2e-14 54.1 9.6 1.2e-14 54.1 9.6 3.0 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KFP16531.1 - 0.00026 21.0 7.1 0.00026 21.0 7.1 3.5 4 0 0 4 4 4 1 bZIP transcription factor Lectin_N PF03954.14 KFP16531.1 - 5.2 6.8 8.1 0.65 9.7 1.0 2.9 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF1708 PF08101.11 KFP16532.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Pkinase_Tyr PF07714.17 KFP16533.1 - 1.9e-86 289.5 0.0 2.5e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP16533.1 - 3.7e-37 128.1 0.0 5.3e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.18 KFP16533.1 - 9.8e-26 89.9 2.5 5.2e-25 87.6 2.5 2.2 2 0 0 2 2 2 1 Kringle domain I-set PF07679.16 KFP16533.1 - 3.3e-18 65.5 0.0 6.4e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP16533.1 - 2e-15 57.2 1.6 2.7e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Fz PF01392.22 KFP16533.1 - 1.5e-11 44.9 2.7 1.5e-11 44.9 2.7 2.1 2 0 0 2 2 2 1 Fz domain Ig_2 PF13895.6 KFP16533.1 - 7.1e-09 35.9 0.0 2.2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP16533.1 - 1.5e-07 31.6 0.3 2.1e-05 24.6 0.3 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP16533.1 - 6.5e-07 29.4 0.0 1.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain DUF2149 PF09919.9 KFP16533.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) TMEM154 PF15102.6 KFP16533.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.1 3 0 0 3 3 3 0 TMEM154 protein family Aminotran_1_2 PF00155.21 KFP16534.1 - 4.1e-34 118.3 0.0 4.8e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PAD PF03068.15 KFP16534.1 - 0.034 13.1 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Cys_Met_Meta_PP PF01053.20 KFP16534.1 - 0.056 12.0 0.0 0.093 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PBD PF00786.28 KFP16535.1 - 1.1e-05 25.7 0.1 1.5e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Complex1_LYR PF05347.15 KFP16537.1 - 1.3e-07 31.5 0.6 1.7e-07 31.1 0.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1577 PF07614.11 KFP16537.1 - 0.0091 15.1 1.1 0.011 14.9 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1577) DUF2570 PF10828.8 KFP16537.1 - 0.029 14.2 0.7 0.036 13.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF2748 PF10871.8 KFP16537.1 - 0.071 11.7 1.2 0.082 11.5 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) HIT PF01230.23 KFP16538.1 - 1.1e-24 87.0 0.0 1.2e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFP16538.1 - 1.2e-14 54.7 0.0 1.3e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TLE_N PF03920.15 KFP16540.1 - 3.3e-53 179.3 10.6 4.7e-53 178.8 10.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFP16540.1 - 8e-17 61.3 18.5 0.015 16.2 0.8 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16540.1 - 9.4e-08 32.3 0.0 0.12 12.7 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP16540.1 - 0.016 14.6 0.0 7.3 5.8 0.2 2.7 2 1 0 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KFP16540.1 - 0.056 12.0 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 KFP16540.1 - 0.1 11.2 0.5 3.5 6.2 0.0 2.5 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_S18 PF01084.20 KFP16540.1 - 0.17 12.1 0.3 0.32 11.2 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 TLE_N PF03920.15 KFP16548.1 - 1.4e-52 177.3 11.0 2e-52 176.7 11.0 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KFP16548.1 - 9.8e-18 64.2 18.1 0.015 16.2 0.8 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16548.1 - 2.3e-08 34.2 0.0 0.16 12.3 0.0 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP16548.1 - 0.012 15.0 0.2 7.3 5.8 0.2 2.8 3 1 0 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KFP16548.1 - 0.035 12.7 0.0 1.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain LCD1 PF09798.9 KFP16548.1 - 0.47 8.9 3.3 0.7 8.3 3.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein PQQ_3 PF13570.6 KFP16548.1 - 0.75 10.4 2.8 21 5.7 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain Y_phosphatase PF00102.27 KFP16551.1 - 2.2e-166 551.1 10.0 6.6e-86 287.7 0.8 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KFP16551.1 - 1.1e-09 38.2 0.1 0.00089 19.1 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP16551.1 - 1.4e-08 35.0 0.4 0.00058 19.9 0.0 2.8 2 1 1 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP16551.1 - 3.1e-07 30.6 0.7 0.004 17.3 0.1 3.3 3 0 0 3 3 3 2 Inositol hexakisphosphate RIFIN PF02009.16 KFP16551.1 - 0.0062 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 KFP16551.1 - 0.012 15.6 8.6 0.067 13.1 8.6 2.1 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KFP16551.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 KFP16551.1 - 0.062 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Y_phosphatase2 PF03162.13 KFP16551.1 - 0.22 11.1 2.1 3.2 7.3 0.0 3.1 3 0 0 3 3 3 0 Tyrosine phosphatase family Adeno_E3_CR2 PF02439.15 KFP16551.1 - 2.6 7.9 6.9 2.4 8.0 2.6 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 MRP-S26 PF14943.6 KFP16552.1 - 3.1e-33 115.1 14.4 3.4e-33 114.9 14.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 MPM1 PF17234.2 KFP16552.1 - 0.086 13.1 2.5 0.097 12.9 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 AP-5_subunit_s1 PF15001.6 KFP16552.1 - 0.78 9.7 5.9 0.9 9.5 5.9 1.1 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Hormone_5 PF00184.17 KFP16553.1 - 5.4e-13 49.6 8.2 5.4e-13 49.6 8.2 1.8 2 1 0 2 2 2 1 Neurohypophysial hormones, C-terminal Domain Hormone_4 PF00220.17 KFP16553.1 - 0.00056 19.6 5.0 0.00056 19.6 5.0 3.0 2 0 0 2 2 2 1 Neurohypophysial hormones, N-terminal Domain U-box PF04564.15 KFP16554.1 - 2.7e-26 91.6 0.1 6.6e-26 90.3 0.1 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 KFP16554.1 - 0.00086 19.2 6.7 0.00086 19.2 6.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP16554.1 - 0.0015 18.3 5.3 0.0058 16.5 5.3 2.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP16554.1 - 0.0025 17.7 5.6 0.012 15.5 5.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP16554.1 - 0.0058 16.6 4.5 0.0058 16.6 4.5 3.2 3 0 0 3 3 3 1 RING-type zinc-finger FYVE_2 PF02318.16 KFP16554.1 - 0.054 13.7 2.6 0.14 12.4 2.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 KFP16554.1 - 0.054 13.4 6.8 0.21 11.5 6.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3496 PF12001.8 KFP16554.1 - 0.064 13.6 0.4 0.19 12.2 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) FYVE PF01363.21 KFP16554.1 - 0.17 12.1 5.9 0.6 10.3 5.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 KFP16554.1 - 0.59 10.3 5.5 1.4 9.1 5.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KFP16554.1 - 1.8 8.8 11.0 1.3 9.2 8.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP16554.1 - 2.7 8.4 13.7 0.085 13.2 5.9 2.6 3 0 0 3 3 3 0 Ring finger domain FAST_2 PF08368.12 KFP16555.1 - 4.5e-19 69.0 0.0 1.3e-18 67.6 0.0 1.9 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFP16555.1 - 2.4e-18 65.8 0.5 2.7e-17 62.5 0.1 3.0 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFP16555.1 - 2.9e-12 46.5 1.0 5.4e-12 45.6 1.0 1.5 1 0 0 1 1 1 1 RAP domain DUF346 PF03984.13 KFP16556.1 - 0.0019 17.9 1.1 0.0034 17.1 1.1 1.3 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) PXT1 PF15214.6 KFP16556.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal testis-specific protein 1 Fez1 PF06818.15 KFP16557.1 - 3.2e-76 256.2 49.5 1e-73 248.1 27.0 2.3 2 0 0 2 2 2 2 Fez1 ATG16 PF08614.11 KFP16557.1 - 0.00035 20.9 8.5 0.00035 20.9 8.5 3.9 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 KFP16557.1 - 0.0018 18.1 2.2 0.0018 18.1 2.2 5.5 4 1 1 5 5 5 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CALCOCO1 PF07888.11 KFP16557.1 - 0.14 11.0 49.0 0.0049 15.8 29.2 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PyocinActivator PF11112.8 KFP16557.1 - 0.24 11.5 2.0 4.6 7.4 0.4 2.8 3 0 0 3 3 3 0 Pyocin activator protein PrtN FAM184 PF15665.5 KFP16557.1 - 1.3 8.8 51.9 0.6 9.9 19.5 3.3 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B ERM PF00769.19 KFP16557.1 - 3 7.6 59.6 0.5 10.1 26.7 3.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Ski2_N PF17911.1 KFP16557.1 - 7.7 6.3 10.7 1.8 8.4 1.3 3.1 3 0 0 3 3 3 0 Ski2 N-terminal region DDRGK PF09756.9 KFP16558.1 - 4.3e-68 228.6 31.9 6.4e-68 228.1 31.9 1.3 1 0 0 1 1 1 1 DDRGK domain PCI PF01399.27 KFP16558.1 - 0.00018 22.0 0.3 0.00033 21.1 0.1 1.6 2 0 0 2 2 1 1 PCI domain FeoC PF09012.10 KFP16558.1 - 0.00041 20.4 0.2 0.57 10.3 0.1 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator HTH_DeoR PF08220.12 KFP16558.1 - 0.0073 16.0 0.2 2.7 7.8 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain UPF0181 PF03701.14 KFP16558.1 - 0.0082 15.8 0.0 0.032 13.9 0.0 2.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) DUF3347 PF11827.8 KFP16558.1 - 0.039 14.1 7.9 0.076 13.2 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Zip PF02535.22 KFP16558.1 - 0.29 10.3 1.5 0.32 10.2 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 KFP16558.1 - 0.31 9.9 17.5 0.44 9.4 17.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 KFP16558.1 - 0.46 10.3 19.1 0.64 9.8 19.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KFP16558.1 - 0.63 8.7 11.3 0.68 8.6 11.3 1.2 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 KFP16558.1 - 0.69 9.1 6.9 1 8.6 6.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Vfa1 PF08432.10 KFP16558.1 - 1.5 9.1 18.1 2.6 8.4 18.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ALMT PF11744.8 KFP16558.1 - 1.8 7.3 9.2 2.2 7.0 9.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 KFP16558.1 - 2.1 7.2 15.1 2.8 6.8 15.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.13 KFP16558.1 - 3.1 6.5 12.8 4.5 6.0 12.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4407 PF14362.6 KFP16558.1 - 3.2 7.0 10.0 4.5 6.5 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_polI_A34 PF08208.11 KFP16558.1 - 3.2 7.8 22.9 5.6 7.0 22.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ribosomal_S25 PF03297.15 KFP16558.1 - 3.7 7.8 16.6 0.086 13.0 3.0 2.9 1 1 1 2 2 2 0 S25 ribosomal protein AAA_23 PF13476.6 KFP16558.1 - 7.6 7.0 18.4 14 6.1 18.4 1.5 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.21 KFP16559.1 - 4.3e-76 255.7 11.2 5.5e-76 255.4 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16559.1 - 2.6e-09 36.9 11.0 4.6e-09 36.0 11.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP16559.1 - 5e-05 23.2 4.7 5e-05 23.2 4.7 1.9 2 1 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP16559.1 - 0.00046 19.9 11.5 0.00046 19.9 11.5 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Haemadin PF09065.10 KFP16559.1 - 0.19 11.5 0.4 0.51 10.2 0.2 1.8 2 0 0 2 2 2 0 Haemadin Insulin_TMD PF17870.1 KFP16559.1 - 2.7 8.1 6.4 0.47 10.6 1.8 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment HCO3_cotransp PF00955.21 KFP16560.1 - 7.6e-160 533.1 7.5 1.1e-159 532.6 7.5 1.2 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 KFP16560.1 - 5.1e-06 26.5 0.0 0.0019 18.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 KFP16560.1 - 3.6e-05 23.7 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain SIR2_2 PF13289.6 KFP16561.1 - 0.013 15.6 1.4 0.053 13.6 0.0 2.7 3 0 0 3 3 3 0 SIR2-like domain Tctex-1 PF03645.13 KFP16561.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 Tctex-1 family Kelch_1 PF01344.25 KFP16562.1 - 8.3e-26 89.3 3.3 4.6e-05 22.9 0.1 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KFP16562.1 - 2.9e-23 81.3 5.9 2.3e-07 30.8 0.0 6.2 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KFP16562.1 - 1.1e-20 73.2 15.4 0.00012 22.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif PSI PF01437.25 KFP16562.1 - 4.6e-17 62.3 114.1 2.8e-12 47.0 10.7 7.9 7 1 0 7 7 5 5 Plexin repeat Lectin_C PF00059.21 KFP16562.1 - 5.7e-17 62.4 0.2 5.7e-17 62.4 0.2 3.4 3 0 0 3 3 2 1 Lectin C-type domain Kelch_3 PF13415.6 KFP16562.1 - 2.5e-16 59.5 5.8 0.0039 17.4 0.0 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP16562.1 - 1.1e-15 57.3 3.0 0.00083 19.3 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain CUB PF00431.20 KFP16562.1 - 7.5e-13 48.8 0.0 2.9e-12 46.9 0.0 2.1 2 0 0 2 2 1 1 CUB domain Kelch_2 PF07646.15 KFP16562.1 - 8.5e-13 47.7 5.6 0.065 13.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Laminin_EGF PF00053.24 KFP16562.1 - 0.0018 18.4 17.0 0.0018 18.4 17.0 8.5 6 3 2 8 8 4 2 Laminin EGF domain PSI_integrin PF17205.3 KFP16562.1 - 0.0087 15.8 8.5 0.0087 15.8 8.5 6.9 6 0 0 6 6 5 2 Integrin plexin domain TMEM100 PF16311.5 KFP16562.1 - 0.018 14.6 0.3 0.044 13.4 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 zf-C2H2 PF00096.26 KFP16568.1 - 9.7e-13 47.8 16.9 0.00012 22.3 3.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP16568.1 - 1e-12 47.9 8.8 2.3e-07 30.9 1.3 4.6 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP16568.1 - 1.8e-09 37.6 16.0 0.0027 18.4 2.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP16568.1 - 0.0078 16.2 6.9 1.1 9.3 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP16568.1 - 0.02 15.2 9.7 0.18 12.1 6.0 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFP16568.1 - 0.071 13.0 11.1 2.9 7.9 0.7 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFP16568.1 - 0.23 11.6 1.5 1.7 8.8 0.9 2.4 1 1 1 2 2 2 0 KIAA1045 RING finger zf-BED PF02892.15 KFP16568.1 - 0.24 11.4 7.7 1.4 9.0 6.4 2.8 2 1 0 2 2 2 0 BED zinc finger zf-RRN7 PF11781.8 KFP16568.1 - 0.39 10.4 2.9 0.79 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_11 PF16622.5 KFP16568.1 - 0.94 9.3 8.4 17 5.3 0.3 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KFP16568.1 - 3.3 8.2 8.5 5.6 7.5 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Xylo_C PF12529.8 KFP16569.1 - 4.6e-68 228.4 0.0 8.4e-68 227.6 0.0 1.5 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.21 KFP16569.1 - 8.9e-46 156.4 0.8 1.6e-45 155.6 0.8 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme FRG2 PF15315.6 KFP16569.1 - 1 9.6 8.9 1.6 8.9 8.5 1.6 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 CarboxypepD_reg PF13620.6 KFP16570.1 - 7.1e-46 154.4 3.2 7.4e-09 35.8 0.3 9.5 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KFP16570.1 - 4.2e-28 97.8 1.1 0.00033 20.8 0.0 9.4 9 0 0 9 9 9 6 SdrD B-like domain DUF2012 PF09430.10 KFP16570.1 - 1.5e-23 83.2 0.1 1.2e-07 31.8 0.0 7.6 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 KFP16570.1 - 6e-19 67.8 5.0 1.9e-05 24.6 0.3 8.4 8 0 0 8 8 8 4 CarboxypepD_reg-like domain SpaA PF17802.1 KFP16570.1 - 5.6e-15 55.4 3.6 0.0013 19.0 0.0 6.8 8 0 0 8 8 8 3 Prealbumin-like fold domain fn3_3 PF14686.6 KFP16570.1 - 9.1e-14 51.0 0.0 0.0015 18.3 0.0 7.0 7 0 0 7 7 7 3 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.13 KFP16570.1 - 3e-06 27.1 0.4 1.3 9.1 0.0 5.2 5 0 0 5 5 5 1 Y_Y_Y domain DUF3823 PF12866.7 KFP16570.1 - 7.6e-05 22.9 0.2 0.3 11.4 0.0 4.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3823) N-terminal domain DUF2846 PF11008.8 KFP16570.1 - 0.00019 21.4 0.2 13 5.9 0.0 4.9 6 0 0 6 6 5 0 Protein of unknown function (DUF2846) Dioxygenase_C PF00775.21 KFP16570.1 - 0.00059 19.3 0.0 12 5.3 0.0 5.1 5 1 0 5 5 5 1 Dioxygenase Big_3 PF07523.12 KFP16570.1 - 0.017 15.4 0.0 29 5.1 0.0 4.4 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF3244 PF11589.8 KFP16570.1 - 0.034 14.2 0.2 21 5.3 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3244) DUF2141 PF09912.9 KFP16570.1 - 0.056 13.4 0.0 10 6.1 0.0 4.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) Cupredoxin_1 PF13473.6 KFP16570.1 - 0.067 13.3 0.0 2.8 8.1 0.0 3.6 2 1 1 3 3 3 0 Cupredoxin-like domain MetallophosN PF16371.5 KFP16570.1 - 0.34 11.2 2.4 33 4.8 0.0 4.5 5 0 0 5 5 5 0 N terminal of Calcineurin-like phosphoesterase ABC_membrane PF00664.23 KFP16571.1 - 2.1e-57 194.9 42.4 5.4e-39 134.5 18.1 4.1 3 1 1 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 KFP16571.1 - 2e-53 180.6 0.2 3.2e-30 105.4 0.1 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFP16571.1 - 1.6e-09 37.5 0.0 7.4e-05 22.3 0.0 3.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFP16571.1 - 2.8e-06 27.4 0.1 0.011 15.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KFP16571.1 - 8.5e-06 25.2 0.2 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KFP16571.1 - 1.5e-05 25.5 0.9 0.0082 16.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KFP16571.1 - 6.2e-05 22.7 0.8 0.26 11.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP16571.1 - 0.00011 22.2 0.3 0.026 14.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFP16571.1 - 0.00011 22.4 4.6 0.29 11.4 0.3 3.4 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KFP16571.1 - 0.00016 20.9 0.1 0.2 10.7 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 KFP16571.1 - 0.00017 21.7 1.2 0.0049 17.0 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_25 PF13481.6 KFP16571.1 - 0.0065 16.1 0.6 1.4 8.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KFP16571.1 - 0.026 13.3 0.9 1.6 7.4 0.1 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MeaB PF03308.16 KFP16571.1 - 0.026 13.5 0.4 1.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KFP16571.1 - 0.032 13.8 0.3 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFP16571.1 - 0.059 13.9 0.1 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFP16571.1 - 0.09 12.8 0.7 19 5.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFP16571.1 - 0.091 12.5 3.6 4.8 6.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KFP16571.1 - 0.15 11.9 2.3 3.6 7.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 KFP16571.1 - 0.17 11.8 1.3 2.8 7.8 0.1 2.5 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 KFP16571.1 - 0.18 10.7 1.8 1.9 7.3 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KFP16571.1 - 0.29 10.3 2.0 14 4.8 0.2 3.1 3 0 0 3 3 3 0 NB-ARC domain CbiA PF01656.23 KFP16571.1 - 0.46 10.5 1.8 1.2 9.2 0.0 2.6 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 KFP16571.1 - 0.49 10.0 3.8 3.4 7.2 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KFP16571.1 - 0.67 10.0 11.6 0.24 11.5 0.4 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain DUF2075 PF09848.9 KFP16571.1 - 0.75 9.0 2.3 10 5.2 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ABC_membrane PF00664.23 KFP16573.1 - 7e-94 314.5 40.6 1.1e-51 176.1 7.2 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP16573.1 - 4.6e-55 185.9 0.0 3.6e-29 102.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFP16573.1 - 8.9e-10 38.4 0.6 0.00054 19.5 0.0 3.8 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFP16573.1 - 1.2e-05 25.3 1.2 0.077 13.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP16573.1 - 1.4e-05 25.6 0.1 0.0024 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFP16573.1 - 1.9e-05 24.6 0.5 0.0066 16.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFP16573.1 - 0.00041 20.0 0.2 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KFP16573.1 - 0.00054 18.9 0.0 0.075 11.8 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KFP16573.1 - 0.00069 18.9 1.3 0.0032 16.8 0.1 2.2 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 KFP16573.1 - 0.005 16.9 3.1 0.03 14.4 0.3 2.8 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KFP16573.1 - 0.0075 16.8 0.7 4.1 7.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KFP16573.1 - 0.0076 16.1 2.4 3.1 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFP16573.1 - 0.011 15.3 0.1 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFP16573.1 - 0.015 15.1 2.3 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 KFP16573.1 - 0.029 14.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 KFP16573.1 - 0.03 14.6 3.3 2.1 8.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KFP16573.1 - 0.062 13.5 0.8 24 5.2 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFP16573.1 - 0.071 13.2 2.6 4.7 7.2 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KFP16573.1 - 0.091 11.9 1.5 12 5.0 0.1 2.8 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KFP16573.1 - 0.094 11.9 0.3 3 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KFP16573.1 - 0.16 10.9 1.0 9 5.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KFP16573.1 - 0.18 11.5 1.3 11 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KFP16573.1 - 0.21 11.1 0.6 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FOP_dimer PF09398.10 KFP16574.1 - 3.3e-25 88.1 0.1 4.9e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KFP16574.1 - 3.4e-07 29.2 0.1 6.6e-07 28.2 0.1 1.5 1 1 0 1 1 1 1 LisH LisH PF08513.11 KFP16574.1 - 0.05 13.6 1.6 0.11 12.5 0.8 1.9 2 0 0 2 2 2 0 LisH NUDE_C PF04880.13 KFP16575.1 - 4.7e-44 151.0 4.0 4.7e-44 151.0 4.0 2.4 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.10 KFP16575.1 - 0.0019 18.3 7.7 0.0019 18.3 7.7 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like PRKG1_interact PF15898.5 KFP16575.1 - 0.0084 17.0 10.8 0.0084 17.0 10.8 3.3 1 1 2 3 3 3 2 cGMP-dependent protein kinase interacting domain HIP1_clath_bdg PF16515.5 KFP16575.1 - 0.015 15.9 10.6 0.015 15.9 10.6 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 KFP16575.1 - 0.02 15.0 34.6 0.17 11.9 10.1 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 KFP16575.1 - 0.19 12.4 24.5 3 8.5 5.7 3.5 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 KFP16575.1 - 0.88 9.8 39.0 0.57 10.4 21.5 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KFP16575.1 - 1.4 7.0 29.7 1.9 6.6 18.1 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2514 PF10721.9 KFP16575.1 - 2.3 8.2 10.2 0.36 10.9 4.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2514) GAS PF13851.6 KFP16575.1 - 2.8 7.2 32.9 0.3 10.4 19.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KFP16575.1 - 2.8 8.2 20.3 0.46 10.8 8.1 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) ADIP PF11559.8 KFP16575.1 - 2.8 8.0 31.9 0.91 9.6 9.3 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KFP16575.1 - 3.8 7.6 11.4 1.2 9.2 4.4 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 KFP16575.1 - 5.8 6.4 30.8 1.4 8.5 6.1 2.7 1 1 1 2 2 2 0 PspA/IM30 family Titin_Ig-rpts PF06582.12 KFP16575.1 - 6 6.9 9.5 0.6 10.1 0.9 3.4 3 0 0 3 3 3 0 Titin repeat Fez1 PF06818.15 KFP16575.1 - 6.6 7.1 29.9 0.21 12.1 11.5 2.3 1 1 1 2 2 2 0 Fez1 OST-HTH PF12872.7 KFP16576.1 - 9.6e-70 230.4 0.8 1.3e-13 50.5 0.0 8.4 8 0 0 8 8 8 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.8 KFP16576.1 - 7.2e-41 138.2 0.5 2.2e-40 136.6 0.4 2.0 2 0 0 2 2 2 1 Limkain b1 NYN PF01936.18 KFP16576.1 - 7.3e-19 68.7 0.0 1.7e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 NYN domain RRM_1 PF00076.22 KFP16576.1 - 5.4e-08 32.5 0.0 0.00028 20.7 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP16576.1 - 0.004 16.7 0.0 1.4 8.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlbD PF06289.11 KFP16576.1 - 0.65 9.6 3.5 1.2 8.8 0.8 2.5 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins DUF3585 PF12130.8 KFP16577.1 - 2e-17 63.6 20.2 4.4e-17 62.5 20.2 1.6 1 1 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Ribosomal_60s PF00428.19 KFP16577.1 - 0.13 12.9 0.1 0.13 12.9 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF5415 PF17436.2 KFP16577.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.6 2 2 0 2 2 2 0 Family of unknown function (DUF5415) MRPL52 PF18699.1 KFP16577.1 - 3.9 7.7 9.6 1.2 9.4 4.1 2.2 1 1 1 2 2 2 0 Mitoribosomal protein mL52 FlxA PF14282.6 KFP16577.1 - 4.6 7.3 10.1 0.34 10.9 4.4 1.9 3 0 0 3 3 3 0 FlxA-like protein Histone_HNS PF00816.21 KFP16577.1 - 5.5 7.9 7.1 0.92 10.4 3.1 1.9 2 1 0 2 2 2 0 H-NS histone family DUF572 PF04502.13 KFP16577.1 - 9 5.8 12.8 12 5.4 12.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) Pyridoxal_deC PF00282.19 KFP16578.1 - 3.1e-12 45.9 0.0 2.6e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain KIAA1430 PF13879.6 KFP16578.1 - 4.3 8.2 8.7 23 5.8 0.2 3.5 3 0 0 3 3 3 0 KIAA1430 homologue N_Asn_amidohyd PF14736.6 KFP16579.1 - 3.3e-121 403.6 0.0 3.8e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase RRN3 PF05327.11 KFP16580.1 - 1.4e-133 446.4 0.9 1.6e-133 446.2 0.9 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_L1 PF00687.21 KFP16581.1 - 1.6e-53 181.5 0.6 1.9e-53 181.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GTP_EFTU PF00009.27 KFP16582.1 - 7.2e-47 159.4 0.0 1.4e-46 158.5 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFP16582.1 - 2.8e-32 111.3 2.9 3.4e-32 111.1 0.2 2.6 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFP16582.1 - 2.6e-08 34.1 0.1 8e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP16582.1 - 0.00062 19.8 0.1 0.0028 17.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 KFP16582.1 - 0.059 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Arf PF00025.21 KFP16582.1 - 0.062 12.7 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RUN PF02759.19 KFP16584.1 - 1.8e-25 89.5 0.1 3.2e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 RUN domain UPF0054 PF02130.17 KFP16584.1 - 0.025 14.4 0.2 0.07 12.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 PX PF00787.24 KFP16585.1 - 1.5e-18 66.8 1.1 1.5e-18 66.8 1.1 2.3 3 0 0 3 3 3 1 PX domain kleA_kleC PF17383.2 KFP16585.1 - 0.047 14.0 3.5 0.11 12.8 3.5 1.7 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A TSC22 PF01166.18 KFP16585.1 - 0.1 12.9 8.9 0.19 12.0 1.9 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KFP16585.1 - 0.16 12.1 9.2 2.9 8.1 1.6 3.1 2 0 0 2 2 2 0 bZIP transcription factor FUSC PF04632.12 KFP16585.1 - 0.28 9.7 2.3 0.48 8.9 2.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family PXA PF02194.15 KFP16585.1 - 1.8 8.5 5.3 10 6.1 5.3 2.1 1 1 0 1 1 1 0 PXA domain Phage_GP20 PF06810.11 KFP16585.1 - 2 8.2 6.1 0.21 11.4 0.7 2.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 ALMT PF11744.8 KFP16585.1 - 2.2 7.0 6.1 3.7 6.3 6.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter MCD_N PF17408.2 KFP16585.1 - 3 8.0 7.5 8.9 6.5 0.2 3.7 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain BRE1 PF08647.11 KFP16585.1 - 4.1 7.6 11.7 1.6 8.8 4.1 3.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase NYD-SP28_assoc PF14775.6 KFP16585.1 - 8.5 6.6 12.6 2.3 8.4 0.8 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain Metallophos PF00149.28 KFP16586.1 - 5e-14 53.3 1.8 7.4e-14 52.7 1.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP16586.1 - 0.00027 21.2 0.0 0.00045 20.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shisa PF13908.6 KFP16588.1 - 7.6e-41 140.4 1.0 9.1e-41 140.2 1.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.11 KFP16588.1 - 0.07 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein RVT_1 PF00078.27 KFP16591.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ERCC4 PF02732.15 KFP16593.1 - 4.7e-25 88.6 0.0 1.4e-24 87.1 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.6 KFP16593.1 - 0.00046 20.7 0.0 0.0016 19.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain T2SSM_b PF10741.9 KFP16593.1 - 0.029 14.2 0.1 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b APC1_C PF18122.1 KFP16593.1 - 0.037 14.0 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF4110 PF13422.6 KFP16593.1 - 0.052 13.6 0.5 0.052 13.6 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) SRP14 PF02290.15 KFP16593.1 - 0.062 13.7 1.9 0.27 11.6 1.9 2.1 1 0 0 1 1 1 0 Signal recognition particle 14kD protein CAF1 PF04857.20 KFP16596.1 - 5.8e-88 295.1 1.8 5.8e-88 295.1 1.8 1.8 2 0 0 2 2 2 1 CAF1 family ribonuclease RNA_bind PF08675.11 KFP16596.1 - 1.4e-33 114.7 0.2 2.8e-33 113.8 0.2 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.22 KFP16596.1 - 1.9e-06 27.8 0.0 5.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 R3H domain NCBP3 PF10309.9 KFP16596.1 - 0.015 15.1 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 RRM_1 PF00076.22 KFP16596.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LUD_dom PF02589.15 KFP16596.1 - 0.081 12.6 0.3 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 LUD domain VIT PF08487.10 KFP16596.1 - 0.13 12.5 1.7 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain SAM_1 PF00536.30 KFP16597.1 - 2.7e-10 40.5 0.0 5.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.6 KFP16597.1 - 3.8e-08 33.4 13.6 7.4e-08 32.4 12.5 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KFP16597.1 - 7.2e-08 32.2 13.8 1.4e-07 31.2 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP16597.1 - 7.6e-08 32.1 13.3 1.6e-07 31.0 13.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP16597.1 - 2.1e-06 27.5 8.1 3.6e-06 26.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP16597.1 - 4.9e-06 26.5 11.2 1.4e-05 25.0 11.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger SAM_2 PF07647.17 KFP16597.1 - 2.5e-05 24.3 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-RING_2 PF13639.6 KFP16597.1 - 3.6e-05 24.0 14.6 7.3e-05 23.0 14.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KFP16597.1 - 0.016 15.0 4.8 0.016 15.0 4.8 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFP16597.1 - 0.017 15.2 4.2 0.044 13.8 4.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1435 PF07256.12 KFP16597.1 - 0.021 14.9 0.7 0.36 10.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1435) zf-rbx1 PF12678.7 KFP16597.1 - 0.031 14.6 10.4 0.072 13.4 10.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP16597.1 - 0.034 14.1 11.5 0.073 13.0 11.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP16597.1 - 0.067 13.1 10.3 0.16 11.9 10.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFP16597.1 - 0.17 12.0 7.6 0.24 11.5 6.6 1.7 2 0 0 2 2 1 0 zinc RING finger of MSL2 Phospholip_A2_1 PF00068.19 KFP16598.1 - 6.3e-35 120.0 17.2 7.1e-35 119.9 17.2 1.0 1 0 0 1 1 1 1 Phospholipase A2 TPR_1 PF00515.28 KFP16599.1 - 9e-07 28.5 3.7 0.052 13.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.24 KFP16599.1 - 3.7e-05 23.5 1.9 3.7e-05 23.5 1.9 4.2 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP16599.1 - 0.0003 20.7 2.4 0.0003 20.7 2.4 4.0 3 0 0 3 3 3 1 Zinc finger domain TPR_2 PF07719.17 KFP16599.1 - 0.00031 20.6 1.5 0.89 9.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-CCCH_4 PF18044.1 KFP16599.1 - 0.00067 19.4 1.8 0.00067 19.4 1.8 5.0 4 0 0 4 4 4 2 CCCH-type zinc finger zf-C2H2_jaz PF12171.8 KFP16599.1 - 0.0019 18.4 6.7 0.0019 18.4 6.7 2.2 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP16599.1 - 0.024 15.0 1.9 0.024 15.0 1.9 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TPR_11 PF13414.6 KFP16599.1 - 0.028 14.1 0.2 11 5.8 0.0 2.6 2 0 0 2 2 2 0 TPR repeat zf-met PF12874.7 KFP16599.1 - 0.029 14.7 6.3 0.098 13.1 6.3 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ANAPC3 PF12895.7 KFP16599.1 - 0.03 14.5 2.3 0.12 12.6 2.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFP16599.1 - 0.12 12.6 0.3 0.66 10.3 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP16599.1 - 0.13 12.7 0.7 0.3 11.5 0.7 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP16599.1 - 0.15 12.6 0.8 0.34 11.4 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP16599.1 - 0.16 12.3 1.8 17 5.8 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 KFP16600.1 - 5.7e-23 80.9 0.1 4.2e-11 42.7 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.6 KFP16600.1 - 1.5e-06 28.3 0.8 0.00094 19.3 0.0 3.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 KFP16600.1 - 3.8e-05 23.7 0.4 0.17 11.8 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP16600.1 - 0.00013 22.2 0.3 0.17 12.2 0.1 3.3 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP16600.1 - 0.00041 20.8 0.4 6 7.4 0.1 4.0 3 1 0 3 3 3 1 Thioredoxin-like domain Macoilin PF09726.9 KFP16600.1 - 0.051 12.1 19.9 0.013 14.1 16.7 1.3 1 1 0 1 1 1 0 Macoilin family DUF836 PF05768.14 KFP16600.1 - 0.059 13.8 0.0 0.24 11.9 0.0 2.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HAUS-augmin3 PF14932.6 KFP16600.1 - 0.059 12.9 17.6 0.12 11.9 17.6 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 KFP16600.1 - 0.091 12.6 25.8 0.54 10.1 21.0 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KFP16600.1 - 0.17 12.1 25.6 0.13 12.5 23.0 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KFP16600.1 - 1.1 8.8 13.1 1.7 8.1 13.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 KFP16600.1 - 1.1 9.6 15.8 27 5.1 15.8 2.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 KFP16600.1 - 1.1 9.8 27.0 1.1 9.8 25.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFP16600.1 - 1.1 9.5 22.8 0.29 11.4 18.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Aida_N PF08910.10 KFP16600.1 - 2.6 8.5 10.5 0.25 11.7 4.2 2.4 3 0 0 3 3 2 0 Aida N-terminus Cnn_1N PF07989.11 KFP16600.1 - 3.6 7.8 20.9 9.4 6.5 3.5 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 FUSC PF04632.12 KFP16600.1 - 3.8 5.9 6.5 6.4 5.2 6.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KFP16600.1 - 5.6 6.2 13.1 8.6 5.6 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KFP16600.1 - 9.6 6.3 9.0 50 3.9 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SNN_transmemb PF09049.10 KFP16601.1 - 1.7e-21 75.8 8.8 2.2e-21 75.4 8.8 1.1 1 0 0 1 1 1 1 Stannin transmembrane SNN_cytoplasm PF09051.10 KFP16601.1 - 5.1e-21 74.2 0.4 6.7e-21 73.8 0.4 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic SNN_linker PF09050.10 KFP16601.1 - 2.1e-20 72.1 2.8 2.9e-20 71.7 2.8 1.2 1 0 0 1 1 1 1 Stannin unstructured linker DUF5337 PF17272.2 KFP16601.1 - 0.031 14.1 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5337) LapA_dom PF06305.11 KFP16601.1 - 0.062 13.1 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF202 PF02656.15 KFP16601.1 - 0.11 13.0 0.6 0.14 12.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Lipocalin_7 PF14651.6 KFP16603.1 - 2.1e-35 121.4 1.5 2.3e-35 121.3 1.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.23 KFP16603.1 - 5.7e-15 55.8 1.0 6.4e-15 55.6 1.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PALP PF00291.25 KFP16604.1 - 1.4e-15 57.5 0.0 3.6e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 KFP16604.1 - 5.4e-09 36.1 0.0 2.8e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus DUF4715 PF15835.5 KFP16604.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) Glyco_transf_56 PF07429.11 KFP16604.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 7tm_1 PF00001.21 KFP16608.1 - 4e-66 223.0 28.8 4.6e-66 222.8 28.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16608.1 - 4.6e-05 22.9 32.5 0.00067 19.1 32.5 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP16608.1 - 0.0038 17.0 7.1 0.0038 17.0 7.1 2.5 2 1 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP16608.1 - 0.01 15.5 32.7 0.02 14.5 31.4 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF5366 PF17328.2 KFP16608.1 - 0.042 14.0 1.0 0.042 14.0 1.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5366) Pkinase PF00069.25 KFP16609.1 - 1.1e-51 175.8 0.0 7.1e-38 130.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16609.1 - 3e-31 108.7 0.0 3e-23 82.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.6 KFP16609.1 - 3.9e-07 29.9 0.1 0.0012 18.5 0.1 2.5 1 1 1 2 2 2 2 PQQ-like domain Kinase-like PF14531.6 KFP16609.1 - 6e-05 22.5 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP16609.1 - 0.0016 17.8 0.2 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TRAP-delta PF05404.12 KFP16609.1 - 0.009 15.6 0.4 0.15 11.5 0.1 2.3 2 0 0 2 2 2 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) Pkinase_fungal PF17667.1 KFP16609.1 - 0.012 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFP16609.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 KFP16609.1 - 0.054 14.0 0.1 8.7 7.0 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Flagellar_put PF12611.8 KFP16609.1 - 0.099 12.4 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Putative flagellar Rib_5-P_isom_A PF06026.14 KFP16610.1 - 3.7e-66 222.0 0.0 4.4e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 KFP16610.1 - 0.092 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain CoA_binding PF02629.19 KFP16611.1 - 8.6e-32 109.7 1.6 1.1e-31 109.4 0.2 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFP16611.1 - 2.7e-22 79.2 0.1 4.5e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFP16611.1 - 1.2e-08 34.8 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFP16611.1 - 3.5e-05 24.3 0.0 8.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Patched PF02460.18 KFP16612.1 - 9.6e-97 325.0 14.6 1.3e-96 324.5 14.6 1.1 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFP16612.1 - 1.2e-19 70.7 3.0 1.2e-19 70.7 3.0 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Phage_holin_3_6 PF07332.11 KFP16612.1 - 4.3 7.4 8.5 13 5.9 0.0 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III 7tm_2 PF00002.24 KFP16613.1 - 2.2e-28 99.2 25.2 3.2e-28 98.7 25.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP16613.1 - 7.2e-08 32.8 3.2 7.2e-08 32.8 3.2 1.9 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif SH3_9 PF14604.6 KFP16614.1 - 2.5e-44 148.9 3.9 1.4e-15 56.9 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFP16614.1 - 9.9e-39 130.7 8.0 1.6e-12 46.8 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KFP16614.1 - 2.1e-34 117.0 4.9 1.7e-11 43.6 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain Tmemb_cc2 PF10267.9 KFP16614.1 - 0.014 14.5 0.3 0.024 13.8 0.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Filament PF00038.21 KFP16614.1 - 0.019 14.6 2.5 0.034 13.7 2.5 1.3 1 0 0 1 1 1 0 Intermediate filament protein NRBF2 PF08961.10 KFP16614.1 - 0.039 13.6 5.9 0.13 11.9 5.9 1.8 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator betaPIX_CC PF16523.5 KFP16614.1 - 7.3 6.5 13.0 2.7 7.9 9.6 2.1 2 1 0 2 2 2 0 betaPIX coiled coil 7tm_2 PF00002.24 KFP16615.1 - 1.2e-30 106.6 22.1 2.1e-30 105.8 22.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ig_3 PF13927.6 KFP16615.1 - 1.3e-13 51.4 13.2 1.3e-09 38.5 0.3 3.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP16615.1 - 1.1e-12 47.9 3.6 2.1e-10 40.5 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin I-set domain GPS PF01825.21 KFP16615.1 - 2.6e-12 47.1 5.7 2.6e-12 47.1 5.7 2.7 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif ig PF00047.25 KFP16615.1 - 4.8e-12 45.9 15.9 2.9e-09 37.0 0.6 4.0 3 0 0 3 3 3 2 Immunoglobulin domain SEA PF01390.20 KFP16615.1 - 5.2e-10 39.3 0.3 6.3e-09 35.9 0.0 2.9 2 0 0 2 2 2 1 SEA domain Ig_2 PF13895.6 KFP16615.1 - 5.8e-10 39.4 11.5 6e-07 29.7 0.4 3.9 3 0 0 3 3 3 2 Immunoglobulin domain GAIN PF16489.5 KFP16615.1 - 2.5e-07 30.4 3.2 8.8e-07 28.6 3.2 1.9 1 1 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain V-set PF07686.17 KFP16615.1 - 4.5e-05 23.6 4.6 0.093 12.9 0.5 4.6 3 2 0 3 3 3 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP16615.1 - 0.0016 18.4 0.3 0.052 13.6 0.0 3.2 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain DUF4736 PF15883.5 KFP16615.1 - 0.24 11.1 2.7 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Ig_4 PF16680.5 KFP16615.1 - 0.4 11.0 4.5 0.57 10.5 0.2 3.5 3 1 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain TAS2R PF05296.13 KFP16616.1 - 1.8e-62 211.2 37.6 2e-62 211.0 37.6 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) DUF3742 PF12553.8 KFP16616.1 - 0.012 15.8 1.6 1.6 8.9 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) ResB PF05140.14 KFP16616.1 - 0.026 13.3 0.1 0.026 13.3 0.1 1.8 2 0 0 2 2 2 0 ResB-like family Ank_4 PF13637.6 KFP16617.1 - 6.6e-21 74.4 1.0 6.2e-10 39.4 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP16617.1 - 4e-18 65.8 0.0 8.3e-15 55.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP16617.1 - 7.4e-14 50.5 0.1 0.00024 21.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP16617.1 - 2.1e-11 43.8 0.5 0.00027 21.2 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP16617.1 - 8.6e-09 35.5 2.3 0.00026 21.3 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat PAF-AH_p_II PF03403.13 KFP16618.1 - 1.1e-179 596.8 0.0 1.3e-179 596.6 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFP16618.1 - 4.4e-09 35.6 0.0 1.2e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFP16618.1 - 1.4e-05 24.3 0.0 0.021 13.9 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.8 KFP16618.1 - 2.7e-05 23.6 0.0 0.089 12.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP16618.1 - 6.2e-05 22.6 0.0 0.00019 21.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KFP16618.1 - 0.0011 18.7 0.0 0.0048 16.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KFP16618.1 - 0.0016 18.1 0.0 0.0039 16.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KFP16618.1 - 0.008 15.8 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.13 KFP16618.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFP16618.1 - 0.037 13.8 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KFP16618.1 - 0.07 11.8 0.0 0.69 8.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KFP16618.1 - 0.15 12.7 0.0 0.27 11.8 0.0 1.4 2 0 0 2 2 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFP16618.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) TUDOR PF00567.24 KFP16620.1 - 3.3e-151 495.3 4.3 1.6e-31 108.9 0.2 7.4 7 0 0 7 7 7 7 Tudor domain SMN PF06003.12 KFP16620.1 - 4e-13 49.2 0.2 0.0018 17.6 0.0 4.8 4 0 0 4 4 4 3 Survival motor neuron protein (SMN) Agenet PF05641.12 KFP16620.1 - 3.1e-10 40.4 4.1 0.59 10.6 0.0 8.1 8 0 0 8 8 8 1 Agenet domain DUF4537 PF15057.6 KFP16620.1 - 8.7e-10 38.7 0.2 1.4 9.0 0.0 6.5 6 0 0 6 6 6 3 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KFP16620.1 - 8.4e-07 29.1 0.0 0.24 11.5 0.0 4.4 4 0 0 4 4 4 2 SGF29 tudor-like domain Spore_coat_CotO PF14153.6 KFP16620.1 - 0.024 14.6 2.4 7.7 6.4 0.0 4.8 6 0 0 6 6 6 0 Spore coat protein CotO Tudor_FRX1 PF18336.1 KFP16620.1 - 0.025 14.5 0.1 1.3 9.0 0.1 3.0 3 0 0 3 3 3 0 Fragile X mental retardation Tudor domain Myosin_N PF02736.19 KFP16620.1 - 0.054 13.3 1.5 12 5.8 0.1 4.3 6 0 0 6 6 6 0 Myosin N-terminal SH3-like domain Tudor_2 PF18104.1 KFP16620.1 - 0.12 12.1 5.7 4.3 7.1 0.0 4.7 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 KFP16620.1 - 0.12 12.3 0.2 27 4.7 0.0 4.5 5 0 0 5 5 5 0 DNA repair protein Crb2 Tudor domain Mito_carr PF00153.27 KFP16621.1 - 3.8e-67 222.3 0.7 8.7e-21 73.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KFP16622.1 - 7.4e-58 196.4 0.1 1.1e-57 195.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Utp13 PF08625.11 KFP16622.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Calcipressin PF04847.12 KFP16623.1 - 3.8e-64 215.9 0.3 4.7e-64 215.6 0.3 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 KFP16623.1 - 0.013 15.3 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP16623.1 - 0.033 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Phosphodiest PF01663.22 KFP16624.1 - 3.4e-82 276.9 0.6 4e-82 276.6 0.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFP16624.1 - 4.6e-07 29.5 0.0 0.00035 20.1 0.0 2.4 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KFP16624.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 KFP16624.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 PglZ domain DUF1501 PF07394.12 KFP16624.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) GST_C_2 PF13410.6 KFP16625.1 - 7.4e-09 35.5 0.0 2e-08 34.1 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP16625.1 - 4.7e-06 26.9 0.0 8.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFP16625.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP16625.1 - 0.00019 21.6 0.4 0.0012 19.0 0.2 2.4 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP16625.1 - 0.021 15.0 0.7 0.051 13.8 0.3 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TFIID-18kDa PF02269.16 KFP16626.1 - 1.5e-28 98.6 0.4 4.2e-28 97.2 0.4 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Hit1_C PF18268.1 KFP16626.1 - 0.05 13.7 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Hit1 C-terminal DUF2849 PF11011.8 KFP16626.1 - 0.11 13.2 0.1 0.32 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Myb_Cef PF11831.8 KFP16627.1 - 4.9e-86 288.2 4.6 4.9e-86 288.2 4.6 3.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFP16627.1 - 6.9e-18 64.6 5.4 3.9e-09 36.5 1.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP16627.1 - 3.9e-17 62.2 7.3 7.8e-12 45.3 3.5 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Pox_A_type_inc PF04508.12 KFP16627.1 - 4.7 7.2 8.4 1.4 8.9 2.2 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat 7tm_1 PF00001.21 KFP16629.1 - 9.2e-35 120.2 14.9 1.1e-34 120.0 14.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP16629.1 - 6.8e-06 25.6 12.6 1.2e-05 24.9 12.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFP16629.1 - 0.00055 19.3 14.8 0.023 14.0 14.9 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFP16629.1 - 0.091 12.5 7.3 0.21 11.3 7.3 1.7 1 1 0 1 1 1 0 Olfactory receptor MM_CoA_mutase PF01642.22 KFP16630.1 - 7.2e-238 790.3 0.0 8.5e-238 790.0 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KFP16630.1 - 6e-15 55.3 0.1 2e-14 53.7 0.1 1.9 1 0 0 1 1 1 1 B12 binding domain PMBR PF09373.10 KFP16630.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein-binding repeat CENP-Q PF13094.6 KFP16631.1 - 4.2e-15 56.4 16.4 4.2e-15 56.4 16.4 1.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit WXG100 PF06013.12 KFP16631.1 - 0.037 14.2 0.7 0.037 14.2 0.7 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Prominin PF05478.11 KFP16631.1 - 0.049 11.6 12.5 0.073 11.0 12.5 1.2 1 0 0 1 1 1 0 Prominin DUF812 PF05667.11 KFP16631.1 - 0.1 11.4 18.0 0.12 11.3 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Plasmid_RAQPRD PF09686.10 KFP16631.1 - 0.31 11.3 2.7 1.1 9.5 2.7 1.9 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SMBP PF16785.5 KFP16631.1 - 0.39 10.9 4.1 0.94 9.7 4.1 1.6 1 1 0 1 1 1 0 Small metal-binding protein Interfer-bind PF09294.10 KFP16631.1 - 0.56 10.6 3.9 0.64 10.4 0.5 2.2 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF1664 PF07889.12 KFP16631.1 - 8.2 6.5 9.9 0.77 9.8 4.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) p450 PF00067.22 KFP16632.1 - 3.8e-134 447.9 0.0 4.4e-134 447.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP16633.1 - 1e-139 466.3 0.1 1.2e-139 466.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ammonium_transp PF00909.21 KFP16634.1 - 7.6e-77 258.7 22.4 8.8e-77 258.4 22.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AzlD PF05437.12 KFP16634.1 - 1.3 9.2 8.7 4.2 7.6 0.7 3.6 3 1 1 4 4 4 0 Branched-chain amino acid transport protein (AzlD) CAP PF00188.26 KFP16635.1 - 4.1e-27 95.5 4.9 5e-27 95.2 4.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.10 KFP16635.1 - 1.3 9.6 9.7 0.31 11.7 5.5 2.2 2 0 0 2 2 2 0 Crisp RVT_1 PF00078.27 KFP16636.1 - 3.6e-14 52.8 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TF_AP-2 PF03299.14 KFP16637.1 - 4.3e-85 284.7 0.0 7.5e-85 283.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AP-2 TF_AP-2 PF03299.14 KFP16638.1 - 1.9e-87 292.3 0.0 2.6e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 HMG_box_5 PF14887.6 KFP16639.1 - 4.6e-54 180.3 17.4 5.2e-52 173.8 5.6 6.3 5 2 2 7 7 7 3 HMG (high mobility group) box 5 HMG_box PF00505.19 KFP16639.1 - 2.4e-52 175.2 72.5 6.4e-18 64.9 7.5 8.2 6 1 1 7 7 7 6 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP16639.1 - 1.8e-23 82.9 70.6 3.2e-08 34.0 0.2 8.2 7 1 1 8 8 8 6 HMG-box domain Evf PF18270.1 KFP16639.1 - 0.052 13.0 0.2 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Virulence factor Evf ScsC_N PF18312.1 KFP16639.1 - 0.058 13.2 0.9 0.18 11.7 0.9 1.9 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Ins134_P3_kin_N PF17927.1 KFP16639.1 - 0.071 13.5 2.6 6 7.4 0.1 3.1 2 1 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Chlor_dismutase PF06778.12 KFP16639.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.2 3 0 0 3 3 3 0 Chlorite dismutase DHC PF09626.10 KFP16639.1 - 0.68 10.8 10.5 3 8.7 0.2 4.2 3 1 1 4 4 4 0 Dihaem cytochrome c HCO3_cotransp PF00955.21 KFP16640.1 - 2.1e-119 399.6 10.0 2.6e-119 399.4 10.0 1.0 1 0 0 1 1 1 1 HCO3- transporter family RUN PF02759.19 KFP16641.1 - 0.0037 17.2 0.0 0.0093 15.9 0.0 1.7 2 0 0 2 2 2 1 RUN domain UPF0242 PF06785.11 KFP16641.1 - 0.0077 16.4 4.0 0.012 15.7 4.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF5595 PF18077.1 KFP16641.1 - 0.061 13.4 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Mito_carr PF00153.27 KFP16642.1 - 4e-64 212.6 0.2 9e-21 73.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP16642.1 - 0.1 11.7 0.0 0.41 9.8 0.0 1.9 1 1 0 1 1 1 0 Gammaproteobacterial serine protease RIIa PF02197.17 KFP16642.1 - 0.22 11.2 0.7 0.41 10.4 0.7 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Tubulin-binding PF00418.19 KFP16643.1 - 1.2e-59 198.0 30.1 3e-16 59.1 3.1 5.8 5 0 0 5 5 5 5 Tau and MAP protein, tubulin-binding repeat PEHE PF15275.6 KFP16644.1 - 4e-15 56.6 2.8 1.8e-14 54.5 0.1 3.2 2 0 0 2 2 2 1 PEHE domain TPR_1 PF00515.28 KFP16645.1 - 6.7e-46 152.3 13.9 1.2e-09 37.5 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP16645.1 - 7e-33 110.1 14.8 6.4e-06 25.9 0.1 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP16645.1 - 3.8e-32 110.3 25.6 9.9e-23 80.2 5.3 5.5 3 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFP16645.1 - 5.1e-29 98.0 10.2 0.00014 21.8 0.2 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFP16645.1 - 6.3e-27 93.7 4.2 3.2e-07 30.5 0.0 7.1 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP16645.1 - 8.6e-25 86.2 13.9 9.3e-07 28.4 0.1 8.5 4 2 5 9 9 8 5 TPR repeat TPR_17 PF13431.6 KFP16645.1 - 7.8e-23 79.2 9.0 0.0038 17.5 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFP16645.1 - 2.8e-20 72.6 5.1 0.082 13.4 0.0 7.7 5 1 3 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFP16645.1 - 4.2e-19 68.9 0.0 6e-08 33.2 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP16645.1 - 1.6e-16 59.6 0.1 0.011 16.5 0.0 8.6 4 1 5 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP16645.1 - 1.5e-13 50.4 9.0 0.17 12.6 0.0 8.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP16645.1 - 9.6e-12 44.9 0.0 4.7e-05 23.5 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP16645.1 - 8.7e-07 28.6 2.7 4.2 7.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.10 KFP16645.1 - 1.4e-06 27.6 0.9 0.0019 17.3 0.0 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KFP16645.1 - 1.6e-05 24.2 0.0 1.1 8.4 0.0 4.5 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP16645.1 - 0.00013 21.5 0.2 0.2 11.0 0.0 3.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 KFP16645.1 - 0.0071 16.7 0.5 0.14 12.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 KFP16645.1 - 0.014 15.1 0.0 0.31 10.7 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KFP16645.1 - 0.022 14.6 2.9 4.9 7.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.10 KFP16645.1 - 0.032 13.1 0.1 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) SRP_TPR_like PF17004.5 KFP16645.1 - 0.09 12.8 7.9 5.5 7.0 0.5 3.7 3 1 1 4 4 4 0 Putative TPR-like repeat PPTA PF01239.22 KFP16645.1 - 0.1 12.4 2.4 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat DUF2225 PF09986.9 KFP16645.1 - 2.1 8.0 7.4 1.5 8.5 0.2 3.2 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) EF-hand_6 PF13405.6 KFP16646.1 - 2.9e-09 36.1 0.0 0.00074 19.3 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KFP16646.1 - 4.3e-05 22.8 1.2 0.11 12.1 0.0 4.1 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 KFP16646.1 - 0.00015 22.0 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFP16646.1 - 0.0014 19.0 0.0 0.01 16.3 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP16646.1 - 0.054 13.3 0.5 10 6.0 0.1 2.8 1 1 1 2 2 2 0 EF-hand domain pair 7tm_2 PF00002.24 KFP16647.1 - 1.5e-84 283.1 18.7 2e-84 282.8 18.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP16647.1 - 3.3e-15 56.1 4.2 3.3e-15 56.1 4.2 1.8 1 1 1 2 2 2 1 Hormone receptor domain DUF1682 PF07946.14 KFP16648.1 - 3.3e-93 312.4 4.8 5e-93 311.8 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) zf-CCCH PF00642.24 KFP16649.1 - 5e-09 35.8 2.7 5e-09 35.8 2.7 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFP16649.1 - 9.6e-09 35.0 8.9 1.9e-08 34.1 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP16649.1 - 5.7e-08 32.5 10.2 1.2e-07 31.5 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP16649.1 - 4.7e-06 26.4 11.2 1.1e-05 25.2 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP16649.1 - 5.9e-06 26.1 12.9 1.2e-05 25.1 12.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP16649.1 - 1.1e-05 25.7 10.5 2.4e-05 24.5 10.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP16649.1 - 3.6e-05 23.7 9.9 9e-05 22.4 9.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KFP16649.1 - 5.4e-05 23.1 4.4 5.4e-05 23.1 4.4 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFP16649.1 - 0.00038 20.2 2.7 0.00038 20.2 2.7 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KFP16649.1 - 0.00064 19.5 8.0 0.0012 18.6 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP16649.1 - 0.0025 17.9 9.7 0.0025 17.9 9.7 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KFP16649.1 - 0.0091 15.8 4.7 0.023 14.5 4.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFP16649.1 - 0.02 15.0 7.3 0.02 15.0 7.3 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KFP16649.1 - 0.12 12.0 7.7 0.23 11.2 7.7 1.4 1 0 0 1 1 1 0 P-11 zinc finger Pannexin_like PF12534.8 KFP16649.1 - 0.58 9.2 4.8 0.078 12.0 0.8 1.5 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 zf-CCCH_2 PF14608.6 KFP16649.1 - 1.2 9.7 7.7 0.1 13.1 2.5 2.0 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 KFP16649.1 - 4.5 7.6 9.3 23 5.4 9.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain LIM PF00412.22 KFP16650.1 - 2.6e-11 43.5 10.7 2.9e-11 43.4 10.7 1.0 1 0 0 1 1 1 1 LIM domain zf-SNAP50_C PF12251.8 KFP16650.1 - 0.31 10.7 7.5 0.33 10.6 7.5 1.1 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal AMP-binding PF00501.28 KFP16651.1 - 8.8e-81 271.7 0.0 1.1e-80 271.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP16651.1 - 3.2e-14 53.6 0.1 8e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATR13 PF16829.5 KFP16651.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector RRM_1 PF00076.22 KFP16652.1 - 3e-17 62.2 0.0 5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFP16652.1 - 0.026 14.5 0.2 0.055 13.4 0.0 1.6 2 0 0 2 2 2 0 RL domain Nup35_RRM_2 PF14605.6 KFP16652.1 - 0.057 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sedlin_N PF04628.13 KFP16653.1 - 2.6e-33 114.9 0.9 3e-33 114.8 0.9 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFP16653.1 - 3.8e-10 39.9 0.2 4.6e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Sulfatase PF00884.23 KFP16654.1 - 3.1e-79 266.6 0.0 4.2e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP16654.1 - 5.3e-33 114.4 0.0 9.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP16654.1 - 2.4e-08 34.0 0.1 1.5e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFP16654.1 - 0.17 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TFIIIC_delta PF12657.7 KFP16654.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Pribosyltran PF00156.27 KFP16655.1 - 1.1e-12 47.8 0.1 1.7e-12 47.1 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFP16655.1 - 0.0019 17.7 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFP16655.1 - 0.039 13.4 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase p47_phox_C PF08944.11 KFP16655.1 - 0.24 10.8 1.6 0.39 10.2 1.6 1.3 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain CTU2 PF10288.9 KFP16656.1 - 4.9e-10 39.6 0.1 2.9e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 zf_C2HC_14 PF18574.1 KFP16657.1 - 8.3e-14 51.1 3.1 8.3e-14 51.1 3.1 2.2 3 0 0 3 3 2 1 C2HC Zing finger domain zf-Di19 PF05605.12 KFP16657.1 - 1.3e-10 41.4 11.3 3.8e-09 36.7 0.6 2.8 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFP16657.1 - 0.012 15.4 5.4 0.65 9.9 0.2 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_2 PF13240.6 KFP16657.1 - 0.015 15.0 0.2 0.015 15.0 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin PF00301.20 KFP16657.1 - 0.015 15.3 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Rubredoxin zf-ribbon_3 PF13248.6 KFP16657.1 - 0.045 13.2 0.2 0.045 13.2 0.2 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 KFP16657.1 - 0.09 12.6 2.8 0.34 10.8 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 KFP16657.1 - 0.17 12.8 0.6 0.17 12.8 0.6 3.8 4 0 0 4 4 3 0 C2H2-type zinc finger Cmc1 PF08583.10 KFP16657.1 - 0.22 11.5 4.4 6.4 6.9 0.8 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zinc_ribbon_9 PF14369.6 KFP16657.1 - 0.41 11.0 0.1 0.41 11.0 0.1 3.5 3 1 0 3 3 3 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 KFP16657.1 - 0.47 10.5 0.0 0.47 10.5 0.0 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Actin_micro PF17003.5 KFP16657.1 - 0.7 9.0 2.5 3 6.9 0.1 2.0 2 0 0 2 2 2 0 Putative actin-like family zf-C4pol PF14260.6 KFP16657.1 - 0.93 10.0 12.3 0.62 10.6 6.7 2.5 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DNA_RNApol_7kD PF03604.13 KFP16657.1 - 1.4 8.6 5.7 24 4.7 0.0 3.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 KFP16657.1 - 6.2 6.9 18.8 1 9.4 0.3 3.4 2 1 0 2 2 2 0 Double zinc ribbon Zn-C2H2_12 PF18112.1 KFP16657.1 - 8 7.0 10.9 29 5.2 3.4 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KFP16658.1 - 1.7e-17 63.5 3.7 1.7e-17 63.5 3.7 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf_C2HC_14 PF18574.1 KFP16658.1 - 2.8e-07 30.2 0.6 2.8e-07 30.2 0.6 2.0 3 0 0 3 3 2 1 C2HC Zing finger domain UIM PF02809.20 KFP16658.1 - 0.00056 19.7 3.7 0.00092 19.0 3.7 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif zinc_ribbon_2 PF13240.6 KFP16658.1 - 0.00061 19.4 2.3 0.016 14.9 0.2 2.6 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KFP16658.1 - 0.001 18.4 7.8 0.045 13.2 0.0 3.3 3 0 0 3 3 3 2 zinc-ribbon domain zf-H2C2_2 PF13465.6 KFP16658.1 - 0.017 15.5 3.7 0.84 10.2 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-CHCC PF10276.9 KFP16658.1 - 0.022 14.8 0.4 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain Rubredoxin PF00301.20 KFP16658.1 - 0.025 14.6 1.4 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_10 PF10058.9 KFP16658.1 - 0.095 12.4 2.6 0.71 9.7 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_9 PF14369.6 KFP16658.1 - 0.11 12.8 5.1 0.44 10.9 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbon DZR PF12773.7 KFP16658.1 - 0.17 12.0 7.1 0.047 13.7 3.1 2.1 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KFP16658.1 - 0.18 12.7 0.6 0.18 12.7 0.6 3.5 3 1 0 3 3 2 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 KFP16658.1 - 0.22 11.1 5.6 0.57 9.7 0.2 2.3 1 1 1 2 2 2 0 TFIIB zinc-binding Cmc1 PF08583.10 KFP16658.1 - 0.23 11.5 3.4 9.8 6.3 0.2 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4729 PF15866.5 KFP16658.1 - 0.29 10.4 3.8 4.9 6.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) zf-RRN7 PF11781.8 KFP16658.1 - 0.31 10.7 2.6 12 5.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_Tnp_IS1595 PF12760.7 KFP16658.1 - 1.1 9.3 11.0 0.6 10.1 0.5 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Prok-RING_1 PF14446.6 KFP16658.1 - 2.4 8.2 7.0 2.9 7.9 1.2 2.4 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-nanos PF05741.13 KFP16658.1 - 2.6 8.3 7.4 1.8 8.8 4.5 2.2 2 1 0 2 2 2 0 Nanos RNA binding domain FOXP-CC PF16159.5 KFP16658.1 - 3.1 8.5 6.6 6 7.6 0.4 2.5 2 1 1 3 3 2 0 FOXP coiled-coil domain zf-CHY PF05495.12 KFP16658.1 - 3.3 8.3 8.0 1.4 9.5 2.2 2.2 1 1 1 2 2 2 0 CHY zinc finger zf-C2H2_9 PF16293.5 KFP16658.1 - 3.6 7.5 6.7 0.75 9.7 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 KFP16658.1 - 6.4 7.4 8.1 4.1 8.0 0.7 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type MmgE_PrpD PF03972.14 KFP16659.1 - 8.4e-125 416.7 0.0 9.4e-125 416.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF4971 PF16341.5 KFP16659.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Lys_export PF03956.13 KFP16659.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Lysine exporter LysO DJ-1_PfpI PF01965.24 KFP16660.1 - 0.00085 19.2 0.1 0.0032 17.3 0.1 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KFP16660.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CLN5 PF15014.6 KFP16661.1 - 7e-168 557.9 5.8 7.9e-168 557.7 5.8 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Lipase3_N PF03893.16 KFP16661.1 - 0.066 13.2 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 Lipase 3 N-terminal region F-box PF00646.33 KFP16662.1 - 1.5e-08 34.3 2.8 1.7e-08 34.1 0.2 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFP16662.1 - 2.6e-08 33.6 1.4 2.6e-08 33.6 1.4 2.4 3 0 0 3 3 3 1 F-box-like DUF4116 PF13475.6 KFP16662.1 - 0.0083 15.8 0.3 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) F-box_5 PF18511.1 KFP16662.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box SLAIN PF15301.6 KFP16663.1 - 3e-158 527.6 28.7 7.9e-141 470.2 23.0 2.0 1 1 1 2 2 2 2 SLAIN motif-containing family 7tm_1 PF00001.21 KFP16664.1 - 1.1e-39 136.3 10.7 1.6e-39 135.8 10.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16664.1 - 8.5e-10 38.4 12.0 2.1e-09 37.2 12.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP16664.1 - 2.6e-06 27.3 6.2 2.6e-06 27.3 6.2 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP16664.1 - 0.00061 19.6 0.8 0.00061 19.6 0.8 1.7 1 1 0 1 1 1 1 Olfactory receptor PHO4 PF01384.20 KFP16664.1 - 0.065 12.3 1.4 0.092 11.8 1.4 1.3 1 0 0 1 1 1 0 Phosphate transporter family Yae1_N PF09811.9 KFP16665.1 - 2.7e-07 30.2 30.6 6.5 6.5 26.2 4.0 2 1 0 2 2 2 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 KFP16666.1 - 4.2e-11 42.5 0.1 0.00042 20.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP16666.1 - 1.1e-06 28.5 0.0 0.00046 20.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 KFP16666.1 - 0.0002 21.6 0.2 0.00042 20.6 0.2 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFP16666.1 - 0.00088 19.1 2.7 0.0017 18.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP16666.1 - 0.0055 16.7 1.6 0.01 15.9 1.6 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM PF05172.13 KFP16666.1 - 0.1 12.6 0.1 29 4.7 0.0 2.9 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif IRS PF02174.17 KFP16667.1 - 3.1e-31 107.2 0.0 5e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFP16667.1 - 1.5e-10 41.5 0.1 2.9e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP16667.1 - 4.4e-05 23.9 0.1 8.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Rhomboid PF01694.22 KFP16668.1 - 3.4e-18 66.1 6.3 5.6e-18 65.4 6.3 1.4 1 0 0 1 1 1 1 Rhomboid family COPI_assoc PF08507.10 KFP16668.1 - 1.7 8.7 9.4 0.063 13.3 1.0 2.6 3 0 0 3 3 3 0 COPI associated protein Miff PF05644.11 KFP16669.1 - 6.3e-143 475.7 2.1 7e-143 475.6 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff dsrm PF00035.26 KFP16670.1 - 0.0048 17.6 0.0 0.017 15.8 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif ArfGap PF01412.18 KFP16671.1 - 1.2e-10 41.5 0.0 2.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Folate_carrier PF01770.18 KFP16672.1 - 1.6e-175 583.8 18.4 1.9e-175 583.6 18.4 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 KFP16672.1 - 2.4e-13 49.7 13.1 2.4e-13 49.7 13.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.18 KFP16673.1 - 5.7e-147 489.8 25.2 3.7e-79 266.4 4.6 2.0 1 1 1 2 2 2 2 Reduced folate carrier MFS_1 PF07690.16 KFP16673.1 - 2.1e-06 26.9 13.2 0.00019 20.5 2.9 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily IL8 PF00048.20 KFP16674.1 - 1.1e-17 63.9 0.1 1.3e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like WD40 PF00400.32 KFP16675.1 - 3.3e-66 217.6 18.5 7.6e-08 32.9 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16675.1 - 8.4e-23 80.5 0.8 0.0029 17.9 0.0 7.4 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP16675.1 - 1.2e-10 41.3 2.3 0.36 10.1 0.0 5.7 2 2 3 5 5 5 5 WD40-like domain eIF2A PF08662.11 KFP16675.1 - 1.3e-08 35.0 0.3 0.0008 19.3 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP16675.1 - 1.7e-06 27.0 2.5 0.15 10.6 0.0 5.7 2 1 5 7 7 7 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP16675.1 - 0.00091 18.3 7.1 0.058 12.4 0.5 3.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 KFP16675.1 - 0.0032 17.4 0.0 0.59 10.2 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Invasin_D3 PF09134.10 KFP16675.1 - 0.16 12.3 0.6 27 5.2 0.0 2.6 2 0 0 2 2 2 0 Invasin, domain 3 AKAP_110 PF05716.13 KFP16676.1 - 2.8e-08 32.5 0.0 5.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) SmAKAP PF15127.6 KFP16676.1 - 0.00087 20.4 10.6 6.1 8.1 0.0 6.2 5 1 0 5 5 5 1 Small membrane A-kinase anchor protein DNA_pol_B_N PF18094.1 KFP16676.1 - 0.13 12.9 0.0 0.56 10.8 0.0 2.2 1 0 0 1 1 1 0 DNA polymerase beta N-terminal domain PID_2 PF14719.6 KFP16677.1 - 1.9e-18 67.0 0.3 3.1e-18 66.3 0.3 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KFP16677.1 - 8.5e-07 29.1 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) MFS_1 PF07690.16 KFP16678.1 - 5.1e-48 163.8 22.0 3.2e-37 128.3 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 KFP16678.1 - 4 7.1 10.2 1.4 8.6 4.5 2.8 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) C2 PF00168.30 KFP16679.1 - 2.3e-31 108.1 3.8 3.6e-15 56.1 0.1 3.5 2 1 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFP16679.1 - 6e-27 94.7 0.2 9e-17 61.5 0.0 3.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 KFP16679.1 - 3.2e-16 59.7 0.7 3.2e-16 59.7 0.7 3.0 4 0 0 4 4 4 1 PH domain BTK PF00779.19 KFP16679.1 - 5.5e-13 48.5 2.1 1.2e-12 47.4 2.1 1.6 1 0 0 1 1 1 1 BTK motif CEP76-C2 PF15627.6 KFP16679.1 - 9.3e-05 22.0 0.3 0.28 10.7 0.0 2.8 3 0 0 3 3 3 2 CEP76 C2 domain PH_8 PF15409.6 KFP16679.1 - 0.0053 17.0 0.6 0.018 15.3 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_trans_1_2 PF13524.6 KFP16679.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DNA_pol3_beta_2 PF02767.16 KFP16679.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Pkinase PF00069.25 KFP16680.1 - 1e-60 205.3 0.1 1.6e-60 204.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16680.1 - 4.7e-34 117.8 0.3 1e-33 116.7 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RGS PF00615.19 KFP16680.1 - 4.1e-15 56.1 4.3 4.7e-15 55.9 1.7 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 KFP16680.1 - 3.1e-05 22.9 0.0 5.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP16680.1 - 0.00027 20.4 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RVT_1 PF00078.27 KFP16681.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP16681.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Na_K-ATPase PF00287.18 KFP16682.1 - 3e-90 302.2 0.2 3.4e-90 302.1 0.2 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain CdiI_2 PF18593.1 KFP16682.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 CdiI immunity protein DP PF08781.10 KFP16683.1 - 1.3e-61 206.6 3.3 2.4e-61 205.6 3.3 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KFP16683.1 - 1.2e-26 92.5 0.2 3e-26 91.3 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FGGY_N PF00370.21 KFP16684.1 - 2.7e-37 128.7 0.0 8.3e-36 123.8 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFP16684.1 - 2.8e-29 102.3 0.0 6.2e-29 101.1 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain XRN_M PF17846.1 KFP16685.1 - 2.9e-96 323.1 6.7 2.9e-96 323.1 6.7 2.0 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KFP16685.1 - 1.3e-85 286.7 0.0 1.3e-85 286.7 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KFP16685.1 - 4.6e-32 111.4 1.7 1.2e-31 110.0 1.7 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KFP16685.1 - 4.1e-21 74.8 0.0 1.2e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KFP16685.1 - 1.7e-07 31.4 0.0 9.4e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Dicer_dimer PF03368.14 KFP16685.1 - 0.1 12.8 0.1 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Dicer dimerisation domain PI3_PI4_kinase PF00454.27 KFP16686.1 - 8.2e-59 199.4 0.1 1.6e-58 198.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KFP16686.1 - 6.5e-44 150.6 2.9 6.5e-44 150.6 2.9 2.4 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KFP16686.1 - 1.8e-19 69.5 5.0 2.5e-19 69.1 0.1 3.6 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 KFP16686.1 - 2.4e-12 46.4 0.0 4.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KFP16686.1 - 1.2e-06 28.2 2.2 4.4 7.8 0.0 7.2 8 0 0 8 8 8 1 HEAT repeat TPR_15 PF13429.6 KFP16686.1 - 0.061 12.5 1.2 0.45 9.7 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Guanylate_kin PF00625.21 KFP16686.1 - 0.098 12.3 0.1 6.6 6.4 0.0 3.0 2 0 0 2 2 2 0 Guanylate kinase DUF2603 PF10788.9 KFP16686.1 - 0.14 12.1 0.8 0.49 10.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2603) SgrT PF15894.5 KFP16686.1 - 0.16 11.9 2.0 0.42 10.6 0.1 2.5 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT CH PF00307.31 KFP16687.1 - 1.3e-88 292.4 1.5 3.5e-25 88.3 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 KFP16687.1 - 1.9e-09 36.4 1.5 6.4e-06 25.4 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP16687.1 - 7.3e-07 29.5 0.0 2.8e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair CAMSAP_CH PF11971.8 KFP16687.1 - 2e-05 24.3 0.1 0.0045 16.8 0.0 3.2 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 KFP16687.1 - 6.7e-05 22.5 0.6 0.082 12.9 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP16687.1 - 0.0011 18.8 0.4 0.11 12.4 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP16687.1 - 0.0013 18.1 2.5 0.015 14.8 0.1 3.1 3 0 0 3 3 3 1 EF hand TRP_2 PF08344.11 KFP16688.1 - 2.2e-25 88.6 2.0 5.3e-25 87.4 2.0 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 KFP16688.1 - 2.1e-16 59.9 14.0 4e-16 59.0 14.0 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KFP16688.1 - 2.9e-05 24.6 3.5 0.001 19.6 0.2 3.1 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP16688.1 - 0.00011 22.6 0.1 1 10.1 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF2407_C PF13373.6 KFP16688.1 - 0.045 13.9 0.1 0.26 11.4 0.0 2.4 3 0 0 3 3 3 0 DUF2407 C-terminal domain TALPID3 PF15324.6 KFP16688.1 - 0.27 8.9 3.0 0.11 10.2 0.4 1.5 2 0 0 2 2 2 0 Hedgehog signalling target CUB PF00431.20 KFP16689.1 - 6.4e-61 203.5 0.0 2.8e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 CUB domain NTR PF01759.21 KFP16689.1 - 8.6e-16 57.7 0.1 3.4e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 UNC-6/NTR/C345C module CUB_2 PF02408.20 KFP16689.1 - 4.4e-08 32.9 0.2 0.0019 18.0 0.0 2.7 2 0 0 2 2 2 2 CUB-like domain TIMP PF00965.17 KFP16689.1 - 0.0047 16.8 0.1 0.011 15.5 0.1 1.6 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase HlyIII PF03006.20 KFP16690.1 - 4e-14 52.9 2.3 4e-14 52.9 2.3 1.3 2 0 0 2 2 2 1 Haemolysin-III related Surp PF01805.20 KFP16691.1 - 4.8e-19 68.1 0.2 1.3e-18 66.7 0.2 1.8 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 KFP16691.1 - 2.5e-15 56.1 0.0 5.6e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 KFP16691.1 - 6.6e-10 39.0 2.7 6.6e-10 39.0 2.7 3.4 4 0 0 4 4 4 1 cwf21 domain CTK3 PF12243.8 KFP16691.1 - 3.6e-05 23.7 0.4 9.9e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 KFP16691.1 - 0.00088 20.0 0.6 0.0041 17.9 0.2 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SET_assoc PF11767.8 KFP16691.1 - 0.014 15.0 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Sulfotransfer_1 PF00685.27 KFP16692.1 - 4.2e-13 49.4 0.0 5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP16692.1 - 2.5e-05 24.8 0.0 7.3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family GDYXXLXY PF14345.6 KFP16692.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 GDYXXLXY protein Na_H_Exchanger PF00999.21 KFP16693.1 - 1.2e-85 287.6 26.9 2.5e-85 286.6 26.9 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Scramblase PF03803.15 KFP16694.1 - 6.3e-84 280.7 0.2 6.9e-84 280.6 0.2 1.0 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.15 KFP16695.1 - 8e-72 241.1 0.0 8.9e-72 241.0 0.0 1.0 1 0 0 1 1 1 1 Scramblase zf_ZIC PF18366.1 KFP16696.1 - 9.9e-27 92.8 0.9 9.9e-27 92.8 0.9 3.3 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KFP16696.1 - 1.9e-19 69.0 29.9 8e-06 26.0 0.2 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP16696.1 - 6.5e-11 42.1 30.9 1.2e-07 31.8 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP16696.1 - 2.7e-05 24.6 42.5 0.01 16.6 0.2 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP16696.1 - 0.0027 17.9 14.5 0.33 11.3 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP16696.1 - 0.043 14.1 12.0 3.3 8.1 2.7 3.6 1 1 3 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 KFP16696.1 - 0.83 10.1 13.2 0.7 10.4 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFP16696.1 - 3.9 7.6 9.9 14 5.8 0.1 3.4 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KFP16697.1 - 6.6e-09 35.7 20.3 3.9e-06 27.0 3.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP16697.1 - 1.8e-06 28.1 23.7 0.00011 22.4 5.5 3.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.7 KFP16697.1 - 1.3e-05 25.4 5.4 0.00052 20.3 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP16697.1 - 0.00053 20.6 17.9 0.0013 19.4 2.5 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP16697.1 - 0.00058 20.1 6.3 0.02 15.2 0.2 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP16697.1 - 0.025 14.6 2.8 0.025 14.6 2.8 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP16697.1 - 2.1 8.3 5.9 2.1 8.3 0.1 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Macoilin PF09726.9 KFP16697.1 - 6.1 5.3 8.9 7.2 5.0 8.9 1.0 1 0 0 1 1 1 0 Macoilin family 7tm_1 PF00001.21 KFP16698.1 - 9.9e-56 189.0 24.5 9.9e-56 189.0 24.5 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16698.1 - 6.4e-09 35.6 27.4 9.3e-09 35.0 27.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_M14 PF00246.24 KFP16699.1 - 1.5e-94 317.1 0.0 1.8e-94 316.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KFP16699.1 - 4.8e-20 71.7 0.9 1.1e-19 70.6 0.9 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Glyco_transf_22 PF03901.17 KFP16701.1 - 3.5e-52 178.1 23.4 4.4e-52 177.7 23.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Transferrin PF00405.17 KFP16702.1 - 2.4e-220 730.4 8.8 9.3e-117 389.9 0.6 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 KFP16702.1 - 5.1e-13 49.2 0.0 4.4e-05 23.2 0.0 3.1 2 2 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KFP16702.1 - 0.018 14.5 0.0 8.5 5.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 Jiv90 PF14901.6 KFP16702.1 - 0.034 14.3 0.2 8.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone DUF3991 PF13154.6 KFP16702.1 - 0.083 13.3 0.4 6.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) IL12p40_C PF10420.9 KFP16702.1 - 7.4 7.2 10.1 8.5 7.0 0.5 2.9 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus Guanylate_kin PF00625.21 KFP16703.1 - 4.1e-66 222.1 1.6 6.8e-66 221.4 1.6 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 KFP16703.1 - 5.3e-64 212.6 9.0 1.4e-20 73.4 0.2 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFP16703.1 - 2e-30 104.4 2.7 6e-11 42.0 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_assoc PF10600.9 KFP16703.1 - 6.6e-29 100.6 5.2 6.6e-29 100.6 5.2 2.1 2 0 0 2 2 2 1 PDZ-associated domain of NMDA receptors MAGUK_N_PEST PF10608.9 KFP16703.1 - 3.7e-19 69.3 10.7 2.1e-14 54.0 3.4 2.7 1 1 1 2 2 2 2 Polyubiquitination (PEST) N-terminal domain of MAGUK PDZ_2 PF13180.6 KFP16703.1 - 2.6e-18 66.1 2.9 2.9e-05 24.3 0.0 4.0 4 0 0 4 4 4 3 PDZ domain SH3_1 PF00018.28 KFP16703.1 - 2.5e-08 33.4 0.1 7.5e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP16703.1 - 3.9e-08 32.8 0.0 1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP16703.1 - 0.032 14.1 0.0 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 Variant SH3 domain DUF1638 PF07796.11 KFP16703.1 - 0.063 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) adh_short PF00106.25 KFP16704.1 - 1e-41 142.5 0.0 1.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP16704.1 - 9.3e-26 90.8 0.0 1.3e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP16704.1 - 6e-08 32.8 0.0 9.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP16704.1 - 4.5e-06 26.2 0.0 2e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KFP16705.1 - 3.5e-45 153.9 0.0 3.8e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP16705.1 - 8.4e-28 97.5 0.0 1.1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP16705.1 - 6e-08 32.8 0.0 7.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NRBF2 PF08961.10 KFP16705.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Lipocalin PF00061.23 KFP16707.1 - 3.8e-23 82.3 0.1 4.3e-23 82.1 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 KFP16707.1 - 3.3e-22 79.0 0.0 4.9e-22 78.4 0.0 1.3 1 1 0 1 1 1 1 Lipocalin-like domain VDE PF07137.11 KFP16707.1 - 1.1e-06 28.4 0.0 1.4e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Triabin PF03973.13 KFP16707.1 - 5e-05 23.2 0.3 0.00015 21.7 0.3 1.8 1 1 0 1 1 1 1 Triabin IPP-2 PF04979.14 KFP16708.1 - 1.5e-39 135.8 15.4 1.9e-39 135.5 15.4 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) PRAS PF15798.5 KFP16708.1 - 3.9 8.1 8.9 1.4 9.6 4.7 1.9 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 CDC27 PF09507.10 KFP16708.1 - 5.4 6.3 22.4 5.4 6.3 22.1 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 BAR_3 PF16746.5 KFP16709.1 - 2.5e-81 272.9 15.7 4.1e-81 272.2 15.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KFP16709.1 - 2.7e-40 137.1 0.2 2.7e-40 137.1 0.2 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP16709.1 - 1.4e-14 54.5 0.6 1.4e-14 54.5 0.6 1.8 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 KFP16709.1 - 1.7e-12 47.7 0.3 9.7e-09 35.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP16709.1 - 7.5e-10 38.9 0.5 1.6e-06 28.3 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP16709.1 - 2.2e-07 31.0 0.3 0.035 14.6 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KFP16709.1 - 4e-06 26.7 0.1 0.03 14.9 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KFP16709.1 - 3.4e-05 24.3 0.0 0.0068 17.0 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KFP16709.1 - 0.081 13.2 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KFP16709.1 - 0.2 12.1 8.3 0.45 11.0 3.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Glyco_transf_8 PF01501.20 KFP16710.1 - 7.9e-08 32.2 0.1 1e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 MMR_HSR1 PF01926.23 KFP16711.1 - 5e-15 55.6 0.1 2.8e-13 50.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP16711.1 - 3.8e-08 33.4 0.1 0.0092 15.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KFP16711.1 - 1.2e-06 28.1 0.1 0.00046 19.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 KFP16711.1 - 0.00082 18.8 0.0 0.0021 17.4 0.0 1.7 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 KFP16711.1 - 0.015 14.9 0.3 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KFP16711.1 - 0.092 13.1 3.0 0.65 10.4 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KFP16711.1 - 1.2 9.1 7.1 2.2 8.3 0.3 3.4 3 1 1 4 4 4 0 Dynamin family P5-ATPase PF12409.8 KFP16712.1 - 7.7e-38 129.4 2.2 1.5e-37 128.5 0.7 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFP16712.1 - 5.6e-36 123.8 0.1 5.6e-36 123.8 0.1 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFP16712.1 - 1.9e-16 61.0 0.1 3.8e-10 40.4 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP16712.1 - 5.8e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFP16712.1 - 9e-07 28.5 0.0 2.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FapA PF03961.13 KFP16712.1 - 0.032 12.8 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LRR_8 PF13855.6 KFP16713.1 - 8e-80 262.5 58.8 2.6e-17 62.3 0.3 7.3 1 1 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KFP16713.1 - 1.2e-34 117.8 39.6 1.5e-05 25.3 4.0 8.6 5 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP16713.1 - 1.4e-26 93.0 0.0 1e-10 41.6 0.0 3.5 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP16713.1 - 4.3e-20 71.9 14.1 0.00021 20.8 1.3 5.9 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KFP16713.1 - 2.1e-05 24.4 45.0 0.11 13.1 0.1 12.2 12 3 0 12 12 11 3 Leucine Rich Repeat LRRNT PF01462.18 KFP16713.1 - 0.005 16.5 3.6 0.022 14.4 2.7 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Syndecan PF01034.20 KFP16713.1 - 0.015 15.2 2.4 0.028 14.3 2.4 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM132D_C PF15706.5 KFP16713.1 - 0.065 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LRRCT PF01463.24 KFP16713.1 - 0.073 13.7 0.5 0.52 11.0 0.5 2.6 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DtxR PF18357.1 KFP16713.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain SAM_3 PF18016.1 KFP16713.1 - 0.1 12.4 0.1 0.63 9.9 0.0 2.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Mid2 PF04478.12 KFP16713.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Hairy_orange PF07527.13 KFP16714.1 - 2.1e-19 69.4 0.5 3.1e-19 68.9 0.5 1.3 1 0 0 1 1 1 1 Hairy Orange Dynamin_N PF00350.23 KFP16715.1 - 1.6e-38 132.4 0.2 1.6e-38 132.4 0.2 3.0 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 KFP16715.1 - 1.1e-05 25.5 0.2 0.00019 21.5 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP16715.1 - 0.00016 21.2 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KFP16715.1 - 0.0074 16.5 0.0 0.62 10.3 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF1593 PF07632.11 KFP16715.1 - 0.013 15.0 0.1 0.013 15.0 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1593) Ras PF00071.22 KFP16715.1 - 0.027 14.1 0.0 8.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras family PilO PF04350.13 KFP16715.1 - 0.038 14.1 2.0 6.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO AAA_16 PF13191.6 KFP16715.1 - 0.042 14.2 0.6 0.74 10.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 KFP16715.1 - 0.085 13.1 1.0 3.3 7.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ephrin_rec_like PF07699.13 KFP16715.1 - 0.16 11.7 0.6 0.38 10.5 0.6 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like ImpA_N PF06812.12 KFP16715.1 - 0.25 11.4 2.8 4.2 7.5 0.0 3.2 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system FlaC_arch PF05377.11 KFP16715.1 - 9 6.8 7.9 37 4.8 1.9 3.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) E1-E2_ATPase PF00122.20 KFP16716.1 - 5.5e-36 123.8 0.0 1.4e-35 122.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KFP16716.1 - 4.5e-32 110.8 1.3 1.1e-31 109.5 1.3 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KFP16716.1 - 1.8e-09 38.2 0.2 1.4e-06 28.8 0.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP16716.1 - 9.1e-08 31.7 0.0 3.2e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFP16716.1 - 0.00023 21.2 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) TcpE PF12648.7 KFP16716.1 - 0.22 12.1 7.7 0.025 15.1 1.6 2.5 2 0 0 2 2 2 0 TcpE family P5-ATPase PF12409.8 KFP16717.1 - 2.8e-32 111.4 0.3 2.3e-31 108.5 0.4 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFP16717.1 - 6e-32 110.6 0.0 6e-32 110.6 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFP16717.1 - 5e-14 53.1 0.3 2.3e-08 34.6 0.5 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP16717.1 - 7.3e-07 28.8 0.1 4.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFP16717.1 - 3e-06 27.2 0.0 7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2620 PF10941.8 KFP16717.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF2620 LRAT PF04970.13 KFP16718.1 - 4.5e-34 117.5 0.0 5.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 KFP16718.1 - 0.057 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain NLPC_P60 PF00877.19 KFP16718.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 NlpC/P60 family Calici_PP_N PF08405.11 KFP16718.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Viral polyprotein N-terminal VWD PF00094.25 KFP16719.1 - 2.4e-107 356.1 14.1 7.8e-39 133.5 3.9 3.2 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 KFP16719.1 - 4.7e-39 132.7 13.4 3.7e-22 78.5 2.9 5.6 5 1 1 6 6 6 2 C8 domain TIL PF01826.17 KFP16719.1 - 1e-22 80.1 40.2 7.5e-13 48.5 16.7 7.1 8 0 0 8 8 8 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.7 KFP16719.1 - 1.9e-16 59.7 31.8 5.9e-10 38.9 11.1 5.1 4 1 1 5 5 5 2 TILa domain 7tm_1 PF00001.21 KFP16721.1 - 3.8e-43 147.7 25.4 4.6e-43 147.5 25.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP16721.1 - 5e-09 36.2 25.4 1.1e-08 35.1 25.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP16721.1 - 0.0088 15.8 16.0 0.34 10.6 16.0 2.2 1 1 0 1 1 1 1 Olfactory receptor Cadherin PF00028.17 KFP16723.1 - 0 1015.4 54.0 1.2e-22 80.1 0.0 21.7 22 0 0 22 22 21 21 Cadherin domain Laminin_G_2 PF02210.24 KFP16723.1 - 4e-24 85.6 1.1 4.1e-23 82.3 0.1 3.2 3 0 0 3 3 3 1 Laminin G domain RET_CLD1 PF17756.1 KFP16723.1 - 5.5e-18 65.4 1.0 0.01 16.1 0.0 11.0 13 0 0 13 13 13 2 RET Cadherin like domain 1 Laminin_G_1 PF00054.23 KFP16723.1 - 6.7e-18 65.2 0.0 4e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Laminin G domain Cadherin_2 PF08266.12 KFP16723.1 - 5.5e-17 61.4 0.2 0.84 9.5 0.0 12.4 15 0 0 15 15 14 3 Cadherin-like Cadherin_3 PF16184.5 KFP16723.1 - 4.7e-16 58.8 45.8 0.35 10.9 0.3 16.0 17 0 0 17 17 17 6 Cadherin-like EGF PF00008.27 KFP16723.1 - 1.1e-11 44.8 59.1 0.0001 22.5 10.8 4.7 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 KFP16723.1 - 3e-05 24.1 10.7 3e-05 24.1 10.7 4.4 3 1 1 4 4 4 1 Calcium-binding EGF domain Cadherin_4 PF17803.1 KFP16723.1 - 0.00049 20.7 87.9 0.084 13.5 0.4 14.7 15 2 0 15 15 15 6 Bacterial cadherin-like domain hEGF PF12661.7 KFP16723.1 - 0.0011 19.5 52.9 0.0096 16.5 7.8 5.0 4 0 0 4 4 4 2 Human growth factor-like EGF RMI1_C PF16099.5 KFP16723.1 - 0.0056 16.5 0.1 12 5.8 0.0 4.0 4 0 0 4 4 4 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Big_9 PF17963.1 KFP16723.1 - 0.24 12.1 0.0 0.24 12.1 0.0 16.3 17 1 1 18 18 18 0 Bacterial Ig domain MLANA PF14991.6 KFP16723.1 - 0.4 11.0 1.3 0.85 9.9 0.0 2.2 2 0 0 2 2 1 0 Protein melan-A Thymidylate_kin PF02223.17 KFP16728.1 - 1.6e-09 37.7 0.1 1.1e-08 35.0 0.1 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 KFP16728.1 - 0.0005 20.2 0.0 0.00062 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP16728.1 - 0.0065 16.9 0.0 0.018 15.4 0.0 1.5 1 1 1 2 2 2 1 AAA ATPase domain PPK2 PF03976.14 KFP16728.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Radical_SAM PF04055.21 KFP16729.1 - 2.3e-07 31.3 0.0 5.3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KFP16729.1 - 0.00035 20.7 0.0 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KFP16729.1 - 0.0077 16.5 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain IBR PF01485.21 KFP16731.1 - 1.1e-19 70.4 27.2 6.9e-13 48.6 11.6 4.6 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFP16731.1 - 0.022 15.1 7.0 0.022 15.1 7.0 4.9 4 2 1 5 5 5 0 Ring finger domain HLH PF00010.26 KFP16732.1 - 4.4e-14 52.2 0.4 7.1e-14 51.5 0.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KAP_NTPase PF07693.14 KFP16733.1 - 1.2e-108 363.2 0.1 1.7e-108 362.7 0.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.7 KFP16733.1 - 9.3e-76 250.5 2.2 1.5e-13 51.1 0.0 6.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP16733.1 - 1.4e-62 206.9 7.8 4.4e-12 46.0 0.2 10.4 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP16733.1 - 3.9e-59 196.3 0.2 1.4e-10 41.5 0.0 9.5 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KFP16733.1 - 4e-56 185.1 1.6 7.4e-07 29.3 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 KFP16733.1 - 5.2e-49 158.5 0.6 6.7e-06 26.1 0.0 12.4 12 0 0 12 12 12 9 Ankyrin repeat SAM_1 PF00536.30 KFP16733.1 - 0.00091 19.6 0.0 0.0044 17.4 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NACHT PF05729.12 KFP16733.1 - 0.0016 18.4 0.1 0.19 11.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain DUF4988 PF16378.5 KFP16733.1 - 0.06 13.0 0.2 0.57 9.8 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function MgtE PF01769.16 KFP16733.1 - 0.61 10.5 7.3 3.1 8.2 2.0 2.3 2 0 0 2 2 2 0 Divalent cation transporter MBOAT PF03062.19 KFP16735.1 - 7.9e-30 104.4 18.9 2.1e-28 99.7 18.9 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ArfGap PF01412.18 KFP16738.1 - 5.5e-33 113.5 1.4 8.4e-33 112.9 0.2 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFP16738.1 - 1.2e-23 84.1 4.7 2.2e-23 83.2 4.7 1.5 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 KFP16738.1 - 5.3e-19 68.6 4.8 4.4e-10 40.0 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 KFP16738.1 - 3.6e-12 46.7 0.6 1.4e-11 44.9 0.4 2.2 2 0 0 2 2 1 1 PH domain SH3_9 PF14604.6 KFP16738.1 - 8.4e-10 38.4 0.1 1.6e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 KFP16738.1 - 3.8e-09 36.9 1.4 4.1e-05 24.0 0.2 3.2 2 1 2 4 4 3 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KFP16738.1 - 6.5e-09 35.3 1.3 1.5e-08 34.1 0.2 2.2 2 0 0 2 2 2 1 SH3 domain Ank PF00023.30 KFP16738.1 - 1.7e-08 34.5 0.7 0.0012 19.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat SH3_2 PF07653.17 KFP16738.1 - 1.5e-07 31.0 0.1 3.7e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 KFP16738.1 - 1.2e-06 28.3 0.4 0.1 13.2 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 KFP16738.1 - 7.1e-06 26.2 0.1 0.00011 22.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) BAR PF03114.18 KFP16738.1 - 1.5e-05 24.7 1.5 2.7e-05 23.9 1.5 1.4 1 0 0 1 1 1 1 BAR domain PH_9 PF15410.6 KFP16738.1 - 0.0064 16.9 0.2 1.6 9.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFP16738.1 - 0.032 14.1 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain ICAP-1_inte_bdg PF10480.9 KFP16739.1 - 2.3e-128 426.1 6.9 2.6e-128 425.9 6.9 1.0 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.23 KFP16739.1 - 6.7e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YCII PF03795.14 KFP16739.1 - 0.07 13.5 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 YCII-related domain DUF4015 PF13200.6 KFP16739.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain Herpes_UL6 PF01763.16 KFP16739.1 - 0.45 9.0 3.3 3.9 5.9 1.2 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like CPSF73-100_C PF11718.8 KFP16740.1 - 3.2e-55 187.0 0.1 5.7e-55 186.2 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFP16740.1 - 2.8e-34 117.7 0.0 6.3e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KFP16740.1 - 9.4e-22 76.7 0.2 2e-21 75.7 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFP16740.1 - 6.3e-19 68.8 0.2 1.1e-18 68.0 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFP16740.1 - 1.4e-18 67.0 0.0 3.3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KFP16740.1 - 5.1e-08 32.7 0.3 4e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFP16740.1 - 2.9e-06 27.3 0.2 6.3e-05 22.9 0.1 3.1 2 1 1 3 3 3 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFP16740.1 - 0.00072 18.9 0.1 0.0017 17.6 0.1 1.6 1 0 0 1 1 1 1 Putative beta-lactamase-like family DUF1611 PF07755.11 KFP16740.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Lipase_GDSL_2 PF13472.6 KFP16741.1 - 1.9e-22 80.5 0.0 3e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFP16741.1 - 9.6e-18 64.9 0.0 1.1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CP_ATPgrasp_2 PF14403.6 KFP16741.1 - 0.051 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 KFP16741.1 - 0.21 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Reprolysin_5 PF13688.6 KFP16742.1 - 1.8e-36 126.2 0.0 3.5e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFP16742.1 - 8.9e-32 110.6 0.0 1.8e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 KFP16742.1 - 1.1e-22 80.1 16.8 1.1e-22 80.1 16.8 4.1 2 1 0 2 2 2 1 Membrane-proximal domain, switch, for ADAM17 Disintegrin PF00200.23 KFP16742.1 - 4.9e-14 52.9 25.2 4.9e-14 52.9 25.2 3.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KFP16742.1 - 6e-13 49.4 0.1 1.3e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KFP16742.1 - 1.1e-10 41.8 0.3 1.4e-05 25.1 0.1 3.3 2 1 1 3 3 3 2 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KFP16742.1 - 4.7e-07 30.1 0.1 1.2e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_4 PF13583.6 KFP16742.1 - 1.7e-05 24.5 0.1 2.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ER PF01133.17 KFP16742.1 - 0.073 13.1 0.1 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Enhancer of rudimentary 14-3-3 PF00244.20 KFP16743.1 - 4.1e-107 356.7 5.2 4.7e-107 356.6 5.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.15 KFP16743.1 - 0.095 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Peptidase_C98 PF15499.6 KFP16743.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase XhlA PF10779.9 KFP16743.1 - 3.1 8.1 4.8 0.8 10.0 1.0 1.9 2 0 0 2 2 2 0 Haemolysin XhlA zf-RRN7 PF11781.8 KFP16744.1 - 8e-10 38.2 5.3 3.1e-09 36.4 5.3 2.1 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CP2 PF04516.15 KFP16745.1 - 4.1e-81 271.7 2.1 6.1e-81 271.1 2.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor zf-C2H2 PF00096.26 KFP16746.1 - 2.3e-14 52.9 22.2 7.7e-05 22.9 0.7 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP16746.1 - 1.1e-11 44.6 9.6 4.4e-07 30.0 1.6 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP16746.1 - 2.1e-07 31.2 20.6 0.0066 17.2 2.2 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP16746.1 - 0.00034 21.2 8.4 0.61 10.8 0.2 3.8 2 1 2 4 4 4 2 FOXP coiled-coil domain zf_Hakai PF18408.1 KFP16746.1 - 0.015 15.0 0.3 0.015 15.0 0.3 2.7 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 KFP16746.1 - 0.035 14.1 0.8 0.035 14.1 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFP16746.1 - 0.047 14.0 1.3 0.047 14.0 1.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFP16746.1 - 0.41 11.1 7.2 12 6.5 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP16746.1 - 5.8 7.3 13.5 27 5.2 1.7 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 KFP16748.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 KFP16750.1 - 3.4e-28 97.9 3.5 2.7e-17 63.0 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP16750.1 - 5.7e-27 91.2 5.4 3.2e-07 29.4 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP16750.1 - 2.2e-23 80.1 3.7 5.5e-07 29.0 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP16750.1 - 1.2e-21 75.2 6.3 3.3e-07 29.5 0.3 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KFP16750.1 - 8.5e-20 70.4 6.3 3.1e-08 33.4 0.1 3.7 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP16750.1 - 4.4e-07 30.2 0.1 0.0071 16.6 0.0 3.3 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP16750.1 - 4.8e-06 26.5 0.7 0.18 11.8 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KFP16750.1 - 0.0025 17.6 0.4 4.1 7.3 0.1 3.0 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KFP16750.1 - 0.0032 17.6 0.0 1.4 9.1 0.0 2.5 2 1 0 2 2 2 2 Dockerin type I domain Orn_Arg_deC_N PF02784.16 KFP16751.1 - 1.3e-92 309.7 0.0 1.7e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFP16751.1 - 2.6e-20 72.5 0.0 3.9e-20 71.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain NUC153 PF08159.12 KFP16753.1 - 1.3e-12 47.3 0.9 3.1e-12 46.1 0.9 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFP16753.1 - 0.022 15.6 0.0 11 7.1 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Thioredoxin PF00085.20 KFP16755.1 - 5.8e-66 219.0 0.0 1.5e-31 108.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KFP16755.1 - 5.6e-11 42.9 0.6 0.0018 18.7 0.1 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP16755.1 - 2e-07 31.1 0.0 0.0043 17.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.6 KFP16755.1 - 2.3e-07 30.9 0.0 0.13 12.2 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP16755.1 - 3.1e-06 27.4 0.0 0.11 12.8 0.0 3.4 3 2 2 5 5 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KFP16755.1 - 3.2e-06 26.7 0.0 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KFP16755.1 - 0.00036 20.5 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 KFP16755.1 - 0.0014 18.5 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 KFP16755.1 - 0.03 14.1 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 KFP16755.1 - 0.044 13.9 0.1 1.6 8.9 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin HyaE PF07449.11 KFP16755.1 - 0.099 12.6 0.0 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF3228 PF11539.8 KFP16755.1 - 0.15 11.5 0.0 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) LLC1 PF14945.6 KFP16757.1 - 1.9e-07 31.6 4.7 5e-06 27.1 4.7 2.0 1 1 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Exonuc_V_gamma PF04257.14 KFP16757.1 - 0.035 12.3 1.4 0.037 12.3 1.4 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Pkinase PF00069.25 KFP16759.1 - 1.8e-60 204.6 0.0 1.8e-60 204.6 0.0 3.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16759.1 - 1.2e-29 103.4 0.6 5.9e-29 101.1 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.11 KFP16759.1 - 2.3e-25 89.2 14.1 2.3e-25 89.2 14.1 13.1 7 3 6 14 14 14 1 Rho Binding PH PF00169.29 KFP16759.1 - 3e-07 30.9 1.6 0.0001 22.7 0.2 3.0 2 0 0 2 2 2 2 PH domain C1_1 PF00130.22 KFP16759.1 - 9.7e-05 22.2 6.4 0.00021 21.1 6.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KFP16759.1 - 0.00075 19.6 15.4 0.00075 19.6 15.4 10.9 6 4 5 11 11 11 1 Hr1 repeat APH PF01636.23 KFP16759.1 - 0.015 15.2 2.4 0.037 14.0 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFP16759.1 - 0.81 10.4 3.1 4.3 8.1 3.1 2.4 1 1 0 1 1 1 0 Protein kinase C terminal domain E2F_CC-MB PF16421.5 KFP16760.1 - 1.5e-32 111.8 0.5 2.8e-32 110.9 0.5 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFP16760.1 - 7.1e-24 83.7 0.3 1.5e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Med4 PF10018.9 KFP16760.1 - 0.039 13.6 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TrmB PF01978.19 KFP16760.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FerA PF08165.11 KFP16760.1 - 0.084 12.8 0.2 0.25 11.3 0.2 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain GREB1 PF15782.5 KFP16762.1 - 0 3445.7 17.4 0 3445.3 17.4 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer PSCyt3 PF07627.11 KFP16762.1 - 1.3 9.3 4.9 0.88 9.9 0.3 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1588) RVT_1 PF00078.27 KFP16763.1 - 0.001 18.6 0.0 0.0027 17.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nbas_N PF15492.6 KFP16770.1 - 4.4e-174 577.4 0.2 7.2e-174 576.7 0.2 1.4 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Sec39 PF08314.11 KFP16770.1 - 1.7e-29 102.9 11.9 5.4e-17 61.6 0.2 2.8 2 1 1 3 3 3 2 Secretory pathway protein Sec39 ANAPC4_WD40 PF12894.7 KFP16770.1 - 0.012 15.9 0.0 5.5 7.4 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_B562 PF07361.11 KFP16770.1 - 0.14 12.9 0.8 0.58 10.8 0.8 2.1 1 0 0 1 1 1 0 Cytochrome b562 GP67 PF17634.2 KFP16770.1 - 0.44 11.0 2.8 1.2 9.6 2.8 1.6 1 0 0 1 1 1 0 Gene product 67 DEAD PF00270.29 KFP16772.1 - 5e-78 260.9 0.0 7.7e-78 260.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP16772.1 - 2.7e-27 95.3 0.1 1e-26 93.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.28 KFP16772.1 - 9.7e-24 83.8 0.6 1.8e-23 82.9 0.1 1.7 2 0 0 2 2 2 1 SPRY domain CMS1 PF14617.6 KFP16772.1 - 0.0025 17.2 0.1 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFP16772.1 - 0.011 15.7 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1394 PF07159.12 KFP16778.1 - 4.3e-139 462.9 0.7 4.9e-139 462.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) MEIOC PF15189.6 KFP16780.1 - 2.8e-86 287.3 1.9 3.6e-86 286.9 1.9 1.1 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC CAMSAP_CC1 PF17095.5 KFP16780.1 - 0.028 14.3 0.4 0.075 12.9 0.4 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Frizzled PF01534.17 KFP16781.1 - 3.8e-139 463.3 22.9 5e-139 462.9 22.9 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP16781.1 - 1.3e-33 115.9 7.1 3.4e-33 114.6 7.1 1.8 1 0 0 1 1 1 1 Fz domain Piwi PF02171.17 KFP16782.1 - 8.6e-102 340.4 0.0 1.3e-101 339.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KFP16782.1 - 6.5e-35 119.9 0.7 1.1e-34 119.2 0.2 1.6 2 0 0 2 2 2 1 PAZ domain ArgoN PF16486.5 KFP16782.1 - 2.1e-07 31.6 0.0 6.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute GAGE PF05831.11 KFP16782.1 - 2.5e-06 28.0 2.6 5e-06 27.0 2.6 1.5 1 0 0 1 1 1 1 GAGE protein ArgoL1 PF08699.10 KFP16782.1 - 5.2e-05 22.8 0.0 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 1 domain Calici_coat PF00915.20 KFP16782.1 - 0.1 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein SH3_2 PF07653.17 KFP16783.1 - 1.3e-32 111.2 0.0 2.1e-10 40.1 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 KFP16783.1 - 1.1e-27 95.6 3.4 3.6e-12 45.9 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KFP16783.1 - 4.1e-16 58.3 0.1 2e-06 27.3 0.0 3.9 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.21 KFP16783.1 - 6.7e-14 52.0 5.5 0.0003 21.1 0.2 4.2 3 1 0 3 3 3 3 Fibronectin type III domain DUF4527 PF15030.6 KFP16783.1 - 1.5 8.2 10.7 3.5 7.0 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) ADIP PF11559.8 KFP16783.1 - 5.3 7.1 12.1 11 6.1 12.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin PF00804.25 KFP16784.1 - 3.6e-64 216.1 17.8 3.6e-64 216.1 17.8 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KFP16784.1 - 2.4e-19 69.1 1.4 2.4e-19 69.1 1.4 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFP16784.1 - 1.7e-11 44.3 5.8 1.7e-11 44.3 5.8 2.7 1 1 2 3 3 3 1 Syntaxin-like protein DUF3671 PF12420.8 KFP16784.1 - 0.0003 20.8 0.6 0.0003 20.8 0.6 2.1 2 0 0 2 2 1 1 Protein of unknown function FapA PF03961.13 KFP16784.1 - 0.0016 17.2 8.1 0.0016 17.2 8.1 2.1 1 1 1 2 2 2 1 Flagellar Assembly Protein A T2SSF PF00482.23 KFP16784.1 - 0.0017 18.3 4.7 0.017 15.0 0.6 2.7 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein F Prominin PF05478.11 KFP16784.1 - 0.0026 15.8 3.3 0.0026 15.8 3.3 2.0 1 1 0 2 2 2 1 Prominin COG5 PF10392.9 KFP16784.1 - 0.0042 17.3 8.8 0.28 11.4 1.3 2.6 2 1 0 2 2 2 2 Golgi transport complex subunit 5 DUF677 PF05055.12 KFP16784.1 - 0.01 14.8 14.6 0.013 14.4 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Baculo_PEP_C PF04513.12 KFP16784.1 - 0.021 14.9 1.9 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KFP16784.1 - 0.026 15.1 2.2 0.026 15.1 2.2 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF16 PF01519.16 KFP16784.1 - 0.029 14.8 1.2 0.029 14.8 1.2 3.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1845 PF08900.11 KFP16784.1 - 0.05 13.3 4.4 0.045 13.5 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1845) LPP PF04728.13 KFP16784.1 - 0.063 13.7 9.4 5.4 7.5 0.1 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper DUF4855 PF16147.5 KFP16784.1 - 0.083 12.0 3.7 0.063 12.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4855) Lipase_GDSL PF00657.22 KFP16784.1 - 0.092 12.7 3.1 0.091 12.7 1.6 1.7 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase Serine_rich PF08824.10 KFP16784.1 - 0.13 12.2 2.9 0.38 10.7 0.4 2.3 1 1 0 2 2 2 0 Serine rich protein interaction domain DUF2205 PF10224.9 KFP16784.1 - 0.16 11.9 0.3 0.16 11.9 0.3 3.9 4 0 0 4 4 4 0 Short coiled-coil protein AAA_18 PF13238.6 KFP16784.1 - 0.2 12.2 2.5 0.26 11.8 0.1 2.3 2 2 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KFP16784.1 - 0.22 10.1 21.8 0.017 13.8 14.6 1.8 1 1 1 2 2 2 0 AAA domain FH2 PF02181.23 KFP16784.1 - 0.37 9.9 13.5 1.2 8.2 1.2 3.1 3 0 0 3 3 3 0 Formin Homology 2 Domain TipAS PF07739.13 KFP16784.1 - 0.42 11.2 5.3 8.8 6.9 0.5 2.7 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain Mer2 PF09074.10 KFP16784.1 - 0.44 10.3 16.9 0.049 13.5 2.1 2.6 1 1 0 2 2 2 0 Mer2 Mur_ligase_M PF08245.12 KFP16784.1 - 0.64 10.0 9.4 0.46 10.4 1.8 2.4 2 1 0 2 2 2 0 Mur ligase middle domain Sec34 PF04136.15 KFP16784.1 - 0.77 9.6 11.9 0.24 11.3 2.6 3.0 1 1 2 3 3 3 0 Sec34-like family Lzipper-MIP1 PF14389.6 KFP16784.1 - 0.91 9.9 7.4 0.2 12.0 0.6 2.7 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 KFP16784.1 - 1.1 9.6 9.1 1.3 9.4 0.1 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF2207 PF09972.9 KFP16784.1 - 1.4 7.6 6.0 0.22 10.2 0.2 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) MCPsignal PF00015.21 KFP16784.1 - 1.5 8.6 13.8 1.5 8.6 1.1 3.4 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.12 KFP16784.1 - 2.1 8.7 8.2 15 5.9 0.1 3.9 4 1 1 5 5 4 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 KFP16784.1 - 2.3 8.7 14.1 6 7.4 0.3 4.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) K-box PF01486.17 KFP16784.1 - 2.5 8.4 10.6 0.49 10.6 3.7 2.8 2 2 0 2 2 2 0 K-box region Allexi_40kDa PF05549.11 KFP16784.1 - 2.8 7.4 11.6 0.92 9.0 2.3 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 KFP16784.1 - 3.1 8.3 5.5 34 5.0 1.4 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 KFP16784.1 - 3.4 6.8 14.5 1.1 8.4 1.8 2.3 1 1 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 KFP16784.1 - 4 7.5 15.8 20 5.2 0.3 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) FlxA PF14282.6 KFP16784.1 - 4.3 7.4 10.2 0.48 10.4 2.3 2.8 2 1 0 2 2 2 0 FlxA-like protein FlgN PF05130.12 KFP16784.1 - 4.3 7.8 12.0 0.55 10.7 4.3 2.5 1 1 0 2 2 2 0 FlgN protein HSCB_C PF07743.13 KFP16784.1 - 8.8 6.9 14.4 0.18 12.3 1.4 3.7 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.9 KFP16784.1 - 9.1 7.0 13.6 2.2 9.0 2.2 3.0 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) Ras PF00071.22 KFP16785.1 - 5.9e-50 169.0 0.0 7e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP16785.1 - 4.2e-31 107.6 0.0 8.4e-31 106.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP16785.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP16785.1 - 9.9e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFP16785.1 - 0.00026 21.4 0.1 0.00094 19.5 0.1 1.8 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 KFP16785.1 - 0.00081 19.0 0.4 0.0035 16.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP16785.1 - 0.0012 18.2 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP16785.1 - 0.0076 15.4 1.7 1 8.5 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.10 KFP16785.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFP16785.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KFP16785.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KFP16785.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 KFP16785.1 - 0.03 14.6 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute Septin PF00735.18 KFP16785.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 KFP16785.1 - 0.066 13.1 0.1 8.7 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KFP16785.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KFP16785.1 - 0.072 13.5 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFP16785.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain 7tm_2 PF00002.24 KFP16786.1 - 1.2e-54 185.2 19.5 2e-54 184.5 19.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_3 PF13385.6 KFP16786.1 - 7.1e-15 55.5 0.1 1.3e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 KFP16786.1 - 7.3e-13 48.8 1.4 2.2e-12 47.3 1.4 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Dicty_CAR PF05462.11 KFP16786.1 - 2.6e-07 30.1 16.3 4.2e-07 29.4 16.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF2673 PF10880.8 KFP16786.1 - 0.0075 16.4 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2673) DRY_EERY PF09750.9 KFP16788.1 - 1.4e-33 116.0 2.2 1.4e-33 116.0 2.2 4.8 4 1 1 6 6 6 1 Alternative splicing regulator Surp PF01805.20 KFP16788.1 - 1.5e-26 92.1 7.6 4.1e-13 49.1 0.9 2.5 2 0 0 2 2 2 2 Surp module Bindin PF02084.15 KFP16788.1 - 0.07 13.4 0.3 0.07 13.4 0.3 2.2 2 0 0 2 2 2 0 Bindin FANCM-MHF_bd PF16783.5 KFP16788.1 - 4 7.5 8.9 0.12 12.5 1.0 2.6 2 0 0 2 2 2 0 FANCM to MHF binding domain Peptidase_M10 PF00413.24 KFP16789.1 - 3.1e-49 166.9 0.5 6.1e-49 165.9 0.5 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP16789.1 - 2.5e-48 161.8 22.1 8.4e-14 51.2 0.3 5.1 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.18 KFP16789.1 - 1.2e-12 47.8 0.2 3e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M66 PF10462.9 KFP16789.1 - 0.028 13.4 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 KFP16789.1 - 0.056 13.1 1.9 0.83 9.2 1.0 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP16789.1 - 0.45 11.0 1.4 0.83 10.2 1.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.25 KFP16791.1 - 2.1e-64 217.4 3.7 2.7e-64 217.1 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16791.1 - 4.3e-46 157.3 0.1 8e-46 156.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KFP16791.1 - 2.2e-25 89.5 7.2 5.5e-25 88.2 7.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 KFP16791.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP16791.1 - 0.00022 20.9 0.1 0.0004 20.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KFP16791.1 - 0.00027 20.4 0.0 0.00088 18.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP16791.1 - 0.0016 17.3 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP16791.1 - 0.014 15.4 0.0 0.075 12.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family PseudoU_synth_1 PF01416.20 KFP16792.1 - 8.8e-13 48.7 0.0 2.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KFP16792.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) EP400_N PF15790.5 KFP16793.1 - 2e-278 924.1 40.9 2e-278 924.1 40.9 6.6 4 3 1 5 5 5 1 E1A-binding protein p400, N-terminal SNF2_N PF00176.23 KFP16793.1 - 4.8e-48 163.7 2.0 4.8e-48 163.7 2.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain HSA PF07529.13 KFP16793.1 - 4.7e-20 71.7 11.1 4.7e-20 71.7 11.1 3.6 3 1 1 4 4 4 1 HSA Helicase_C PF00271.31 KFP16793.1 - 4e-09 36.8 0.1 1.2e-08 35.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 KFP16793.1 - 5.5e-05 23.3 0.0 0.0002 21.4 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFP16793.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP16793.1 - 0.0032 17.7 2.1 0.0076 16.5 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain CBF PF03914.17 KFP16794.1 - 3.5e-35 121.5 0.7 5.7e-35 120.9 0.7 1.3 1 0 0 1 1 1 1 CBF/Mak21 family Glycos_transf_2 PF00535.26 KFP16796.1 - 3e-26 92.2 0.1 6e-26 91.3 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP16796.1 - 1.9e-20 73.4 0.0 3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP16796.1 - 1.5e-06 28.3 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP16796.1 - 0.0056 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Auts2 PF15336.6 KFP16801.1 - 1.2e-109 365.5 11.7 1.2e-109 365.5 11.7 5.7 6 1 0 7 7 7 3 Autism susceptibility gene 2 protein ATG16 PF08614.11 KFP16803.1 - 0.00076 19.8 27.0 0.00076 19.8 27.0 12.3 2 2 10 12 12 12 4 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KFP16803.1 - 0.0051 16.8 14.8 0.0051 16.8 14.8 12.4 3 1 9 13 13 13 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LEM PF03020.15 KFP16804.1 - 2e-10 40.1 1.1 5.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 LEM domain Ank_5 PF13857.6 KFP16804.1 - 1.5e-09 38.0 0.1 0.00082 19.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP16804.1 - 9.4e-09 35.8 0.1 1.1e-05 25.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Cauli_VI PF01693.16 KFP16804.1 - 0.0001 22.5 0.1 0.00025 21.3 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ank_3 PF13606.6 KFP16804.1 - 0.00057 20.1 0.1 0.11 13.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFP16804.1 - 0.00061 20.3 0.2 0.0028 18.2 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP16804.1 - 0.0028 18.0 0.1 0.28 11.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat DUF406 PF04175.12 KFP16804.1 - 0.037 14.5 0.0 0.23 11.9 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF406) His_Phos_1 PF00300.22 KFP16805.1 - 6.9e-23 81.4 0.4 3.8e-21 75.7 0.4 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DHHC PF01529.20 KFP16806.1 - 1.1e-35 122.6 12.2 3.6e-35 121.0 11.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ran_BP1 PF00638.18 KFP16807.1 - 8.9e-55 184.2 0.4 8.9e-55 184.2 0.4 1.5 2 0 0 2 2 2 1 RanBP1 domain PhaP_Bmeg PF09602.10 KFP16807.1 - 0.037 14.0 1.6 0.037 14.0 1.6 1.6 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF883 PF05957.13 KFP16807.1 - 0.078 13.6 1.7 7.9 7.2 0.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) dsrm PF00035.26 KFP16808.1 - 2.1e-20 73.2 4.0 2.6e-12 47.3 0.0 4.0 3 1 0 3 3 3 2 Double-stranded RNA binding motif DUF4462 PF14692.6 KFP16809.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) TANGO2 PF05742.12 KFP16810.1 - 2.6e-05 24.4 0.0 2.6e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Methyltransf_3 PF01596.17 KFP16811.1 - 2.5e-22 79.1 0.0 3.7e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFP16811.1 - 5.1e-14 53.2 0.0 7.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KFP16811.1 - 0.00023 20.9 0.0 0.00046 19.9 0.0 1.4 2 0 0 2 2 2 1 Cephalosporin hydroxylase Methyltransf_31 PF13847.6 KFP16811.1 - 0.00065 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP16811.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KFP16811.1 - 0.1 13.3 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP16811.1 - 0.1 12.2 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Pyr_redox_2 PF07992.14 KFP16812.1 - 1.8e-49 168.5 0.0 2.8e-49 167.9 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFP16812.1 - 3e-31 107.9 0.0 5.5e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFP16812.1 - 1.2e-11 45.0 0.2 4.3e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP16812.1 - 8.7e-08 31.7 4.8 9.2e-07 28.3 0.7 2.8 2 2 1 4 4 4 1 FAD binding domain Pyr_redox_3 PF13738.6 KFP16812.1 - 3.2e-06 26.6 1.9 0.029 13.6 0.4 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFP16812.1 - 3e-05 22.9 0.3 0.00048 18.9 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KFP16812.1 - 8.8e-05 21.7 0.7 0.00048 19.3 0.7 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFP16812.1 - 0.00052 19.5 0.3 0.00096 18.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFP16812.1 - 0.00054 19.3 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KFP16812.1 - 0.0013 18.0 0.2 0.29 10.2 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP16812.1 - 0.0023 18.1 0.3 0.0067 16.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP16812.1 - 0.0025 17.5 2.5 0.0036 16.9 0.7 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFP16812.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1775 PF07987.11 KFP16812.1 - 0.046 14.0 0.4 7.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) WD40 PF00400.32 KFP16813.1 - 1.5e-22 79.4 8.0 0.00082 20.1 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16813.1 - 3.8e-09 36.7 0.3 0.02 15.2 0.1 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Septin PF00735.18 KFP16815.1 - 4.6e-131 436.2 0.6 5.2e-131 436.1 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP16815.1 - 1.7e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP16815.1 - 3.6e-07 30.3 0.2 1.7e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP16815.1 - 8.3e-06 25.5 0.2 0.028 13.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP16815.1 - 0.00093 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 KFP16815.1 - 0.0078 15.8 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFP16815.1 - 0.0093 16.0 3.6 0.38 10.8 0.0 2.6 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 KFP16815.1 - 0.013 15.7 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP16815.1 - 0.014 15.7 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFP16815.1 - 0.034 13.9 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFP16815.1 - 0.038 14.5 0.2 0.066 13.7 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP16815.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP16815.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFP16815.1 - 0.44 11.0 4.0 2.2 8.8 4.0 1.9 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.14 KFP16816.1 - 1.8e-158 528.7 19.9 2.7e-120 402.6 10.9 3.0 1 1 1 2 2 2 2 CDC45-like protein DUF3848 PF12959.7 KFP16816.1 - 0.047 13.8 0.8 0.55 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) UBA2_C PF16195.5 KFP16816.1 - 0.41 11.4 7.5 7.3 7.3 6.6 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus UFD1 PF03152.14 KFP16817.1 - 6e-80 266.8 0.0 7.2e-80 266.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KFP16817.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 MRP-L28 PF09812.9 KFP16818.1 - 1.8e-49 168.0 6.2 2.2e-49 167.7 6.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF4207 PF13904.6 KFP16818.1 - 0.0002 21.1 8.5 0.00027 20.7 8.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) FliD_N PF02465.18 KFP16818.1 - 0.1 13.3 0.7 7.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4200 PF13863.6 KFP16818.1 - 0.35 11.3 13.9 0.13 12.7 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Hira PF07569.11 KFP16819.1 - 5.2e-58 196.4 0.2 1.3e-57 195.1 0.2 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KFP16819.1 - 2.4e-28 97.8 31.7 2.5e-08 34.4 4.0 8.6 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16819.1 - 2.3e-10 40.6 4.3 0.013 15.8 0.0 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KFP16819.1 - 4.5e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif TFIIIC_delta PF12657.7 KFP16819.1 - 0.032 14.2 1.9 0.42 10.5 0.0 3.4 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Ribonuc_red_lgC PF02867.15 KFP16819.1 - 0.039 12.5 0.9 0.058 11.9 0.9 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain WD40_like PF17005.5 KFP16819.1 - 0.075 12.3 0.0 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Pro_isomerase PF00160.21 KFP16820.1 - 6.6e-52 176.0 0.1 1.3e-51 175.0 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KFP16820.1 - 0.0017 17.8 0.1 0.0017 17.8 0.1 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 KFP16820.1 - 0.004 17.3 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 U-box domain Selenoprotein_S PF06936.11 KFP16820.1 - 2.5 7.9 5.2 6.5 6.5 5.2 1.6 1 1 0 1 1 1 0 Selenoprotein S (SelS) Yippee-Mis18 PF03226.14 KFP16821.1 - 1.1e-12 48.1 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KFP16821.1 - 0.016 15.4 0.2 0.028 14.6 0.2 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.13 KFP16821.1 - 0.057 13.9 2.6 0.43 11.1 2.6 2.0 1 1 0 1 1 1 0 Erv1 / Alr family zf-CHY PF05495.12 KFP16821.1 - 0.076 13.5 6.8 0.27 11.7 6.8 1.9 1 1 0 1 1 1 0 CHY zinc finger Pkinase PF00069.25 KFP16822.1 - 3.8e-63 213.3 0.0 4.3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16822.1 - 7.4e-32 110.6 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP16822.1 - 0.0009 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP16822.1 - 0.011 14.8 0.2 0.021 13.8 0.2 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KFP16822.1 - 0.058 13.0 0.2 0.089 12.4 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KFP16822.1 - 0.059 13.0 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFP16822.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFP16822.1 - 0.09 12.1 0.3 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C PF00481.21 KFP16823.1 - 1.9e-64 217.8 0.0 2.4e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP16823.1 - 0.0051 16.5 0.2 0.035 13.7 0.2 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C HHH_5 PF14520.6 KFP16823.1 - 0.06 14.0 0.1 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Acetyltransf_1 PF00583.25 KFP16823.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Histone PF00125.24 KFP16828.1 - 1.8e-37 128.6 1.9 2e-37 128.5 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP16828.1 - 3e-05 24.1 0.1 3.4e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFP16828.1 - 0.00012 22.4 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP16828.1 - 0.0039 17.4 0.1 0.0055 17.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP16828.1 - 0.045 13.8 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KFP16829.1 - 1.6e-08 34.6 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFP16829.1 - 2.2e-05 24.5 0.2 3.2e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFP16829.1 - 4.2e-05 23.8 0.1 5.5e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFP16829.1 - 0.00016 22.0 0.3 0.00018 21.9 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16829.1 - 0.00025 21.3 0.1 0.00042 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP16829.1 - 0.0054 16.8 0.0 0.0061 16.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFP16829.1 - 0.022 14.7 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFP16829.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 KFP16831.1 - 1.8e-37 128.6 1.9 2e-37 128.5 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP16831.1 - 3e-05 24.1 0.1 3.4e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFP16831.1 - 0.00012 22.4 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP16831.1 - 0.0039 17.4 0.1 0.0055 17.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP16831.1 - 0.045 13.8 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFP16832.1 - 6.8e-26 91.2 0.2 8.4e-26 90.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16832.1 - 8.9e-07 29.1 0.7 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP16832.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFP16832.1 - 0.0034 17.4 0.3 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein Histone_H2A_C PF16211.5 KFP16833.1 - 2.9e-20 71.7 1.8 4.8e-20 71.0 1.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFP16833.1 - 4.5e-15 56.2 0.0 5.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16833.1 - 0.0087 16.3 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KFP16834.1 - 1.6e-08 34.6 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFP16834.1 - 2.2e-05 24.5 0.2 3.2e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFP16834.1 - 4.2e-05 23.8 0.1 5.5e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFP16834.1 - 0.00016 22.0 0.3 0.00018 21.9 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16834.1 - 0.00025 21.3 0.1 0.00042 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP16834.1 - 0.0054 16.8 0.0 0.0061 16.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFP16834.1 - 0.022 14.7 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFP16834.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 KFP16836.1 - 8.4e-27 94.1 0.5 1e-26 93.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16836.1 - 7.3e-07 29.4 1.6 8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KFP16836.1 - 0.0019 18.2 0.3 0.0023 18.0 0.3 1.2 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KFP16836.1 - 0.0024 18.3 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-T_C PF15511.6 KFP16838.1 - 1.6e-08 34.6 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KFP16838.1 - 2.2e-05 24.5 0.2 3.2e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KFP16838.1 - 4.2e-05 23.8 0.1 5.5e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFP16838.1 - 0.00016 22.0 0.3 0.00018 21.9 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP16838.1 - 0.00025 21.3 0.1 0.00042 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP16838.1 - 0.0054 16.8 0.0 0.0061 16.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFP16838.1 - 0.022 14.7 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFP16838.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) AA_permease PF00324.21 KFP16839.1 - 1.8e-52 178.6 19.9 1.1e-39 136.4 6.0 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KFP16839.1 - 8.8e-34 117.2 12.3 1.5e-16 60.5 3.3 3.4 1 1 1 3 3 3 3 Solute carrier family 12 PRA1 PF03208.19 KFP16839.1 - 1.8 8.1 11.1 0.24 11.0 0.2 2.7 2 0 0 2 2 2 0 PRA1 family protein Claudin_2 PF13903.6 KFP16840.1 - 1e-18 67.8 2.6 6.5e-10 39.1 0.1 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP16840.1 - 0.0015 18.5 3.5 0.11 12.3 2.0 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Na_H_Exchanger PF00999.21 KFP16841.1 - 4.1e-75 252.9 36.1 2.4e-74 250.4 36.1 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFP16841.1 - 2.7e-11 43.7 0.1 4.4e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin DUF4569 PF15133.6 KFP16842.1 - 1.1e-98 330.6 4.0 1.4e-98 330.4 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) SH3BGR PF04908.15 KFP16843.1 - 5.7e-23 81.0 0.1 6.8e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein HMG14_17 PF01101.18 KFP16844.1 - 6e-12 46.4 37.1 1.3e-11 45.3 37.1 1.5 1 1 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.14 KFP16844.1 - 5.7 8.0 11.3 16 6.5 11.3 1.7 1 1 0 1 1 1 0 E4 protein PID PF00640.23 KFP16845.1 - 3.6e-32 111.3 0.0 4.7e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KFP16845.1 - 3.4e-18 65.5 0.0 5.4e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Delta_lysin PF05372.11 KFP16845.1 - 0.063 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family CaMBD PF02888.16 KFP16846.1 - 9.9e-20 70.5 4.0 1.8e-19 69.7 4.0 1.4 1 0 0 1 1 1 1 Calmodulin binding domain SK_channel PF03530.14 KFP16846.1 - 0.0013 18.7 4.4 0.0029 17.6 0.4 2.2 2 0 0 2 2 2 1 Calcium-activated SK potassium channel PAS_11 PF14598.6 KFP16847.1 - 2e-37 127.8 0.0 4.2e-33 113.9 0.0 2.4 2 0 0 2 2 2 2 PAS domain NCOA_u2 PF16665.5 KFP16847.1 - 2.2e-33 115.1 18.7 2.2e-33 115.1 18.7 3.4 3 1 0 3 3 2 1 Unstructured region on nuclear receptor coactivator protein SRC-1 PF08832.10 KFP16847.1 - 5.3e-22 78.7 4.2 5.3e-22 78.7 4.2 2.8 2 0 0 2 2 2 1 Steroid receptor coactivator PAS PF00989.25 KFP16847.1 - 2e-09 37.4 0.0 1.8e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFP16847.1 - 3.6e-08 33.6 0.0 0.00021 21.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFP16847.1 - 3e-07 30.6 0.0 7.2e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain DUF4927 PF16279.5 KFP16847.1 - 1.3e-06 29.3 5.2 1.3e-06 29.3 5.2 3.2 4 0 0 4 4 2 1 Domain of unknown function (DUF4927) HLH PF00010.26 KFP16847.1 - 3.4e-06 26.9 0.9 3.4e-06 26.9 0.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 KFP16847.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_12 PF18095.1 KFP16847.1 - 0.031 13.9 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain CXCL17 PF15211.6 KFP16847.1 - 0.2 12.4 3.3 3.5 8.5 0.2 2.6 2 0 0 2 2 2 0 VEGF co-regulated chemokine 1 Pkinase PF00069.25 KFP16848.1 - 3.2e-49 167.7 0.0 1.3e-48 165.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16848.1 - 1.1e-34 119.9 0.4 1.3e-25 90.2 0.0 2.6 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KFP16848.1 - 0.0003 20.8 0.0 0.012 15.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP16848.1 - 0.0019 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KFP16848.1 - 0.022 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC1 family RIO1 PF01163.22 KFP16848.1 - 0.028 14.0 0.0 0.076 12.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family DUF3091 PF11291.8 KFP16848.1 - 0.064 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Pkinase_fungal PF17667.1 KFP16848.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFP16848.1 - 0.09 12.1 0.0 0.36 10.1 0.0 2.0 2 1 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.9 KFP16848.1 - 0.11 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Radical_SAM_C PF16199.5 KFP16849.1 - 1.2e-34 118.1 0.0 2.8e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KFP16849.1 - 9.8e-22 78.1 2.1 6.6e-21 75.4 0.1 3.0 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KFP16849.1 - 4.3e-10 39.9 0.1 8.1e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP16849.1 - 4.7e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP16849.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein F-box-like PF12937.7 KFP16851.1 - 7.2e-09 35.4 5.6 1.2e-08 34.6 5.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP16851.1 - 3.9e-08 33.0 2.6 9.2e-08 31.8 2.6 1.6 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.6 KFP16851.1 - 0.0037 17.5 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Glyco_transf_64 PF09258.10 KFP16852.1 - 2.6e-101 338.0 0.1 4.4e-101 337.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFP16852.1 - 2.6e-56 191.1 0.0 4.7e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Exostosin family DUF812 PF05667.11 KFP16852.1 - 0.014 14.3 0.9 0.022 13.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 KFP16852.1 - 0.017 15.3 7.2 0.028 14.5 7.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 KFP16852.1 - 0.021 15.0 2.8 0.044 14.0 2.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFP16852.1 - 0.029 14.4 2.3 0.06 13.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KFP16852.1 - 0.048 13.9 4.9 0.096 12.9 4.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.7 KFP16852.1 - 0.05 13.1 4.6 0.079 12.5 4.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 KFP16852.1 - 0.12 12.4 12.0 0.015 15.3 8.0 1.5 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.13 KFP16852.1 - 0.15 12.3 5.9 0.075 13.3 3.3 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 EzrA PF06160.12 KFP16852.1 - 0.16 10.1 4.0 0.25 9.5 4.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Noelin-1 PF12308.8 KFP16852.1 - 0.25 11.3 1.9 0.57 10.2 1.9 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein BRE1 PF08647.11 KFP16852.1 - 0.32 11.1 6.5 0.59 10.2 6.5 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase CAMSAP_CC1 PF17095.5 KFP16852.1 - 0.34 10.8 1.6 0.66 9.9 1.6 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin TMPIT PF07851.13 KFP16852.1 - 0.42 9.8 3.1 0.85 8.8 3.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein Tropomyosin_1 PF12718.7 KFP16852.1 - 0.5 10.5 6.2 0.98 9.6 6.2 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF724 PF05266.14 KFP16852.1 - 1.9 8.3 4.9 3.5 7.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KFP16852.1 - 2 7.2 7.7 3.7 6.3 7.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.8 KFP16852.1 - 4.8 7.6 7.5 9.8 6.6 7.5 1.4 1 0 0 1 1 1 0 YlqD protein Lactamase_B_6 PF16661.5 KFP16853.1 - 3e-16 59.4 0.4 2.8e-14 53.0 0.1 3.1 3 1 1 4 4 4 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KFP16853.1 - 1.4e-06 28.6 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 KFP16853.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family HNF-1_N PF04814.13 KFP16854.1 - 9.8e-63 212.3 3.4 2.1e-62 211.2 3.4 1.6 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFP16854.1 - 1.6e-10 40.7 1.4 7.8e-10 38.5 0.1 2.8 3 1 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 KFP16854.1 - 2.9e-05 23.9 0.6 0.0022 17.9 0.1 3.0 2 1 0 2 2 2 1 Homeobox KN domain HTH_37 PF13744.6 KFP16854.1 - 0.00099 19.0 0.4 0.00099 19.0 0.4 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KFP16854.1 - 0.0027 17.7 0.4 0.046 13.7 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KFP16854.1 - 0.0029 17.6 0.1 0.0066 16.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 KFP16854.1 - 0.012 15.1 0.2 0.057 13.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AbiJ_NTD3 PF18860.1 KFP16854.1 - 0.014 15.0 0.4 0.24 10.9 0.1 2.5 3 0 0 3 3 3 0 AbiJ N-terminal domain 3 HTH_31 PF13560.6 KFP16854.1 - 0.017 15.4 1.9 0.074 13.4 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF494 PF04361.13 KFP16854.1 - 0.036 14.0 0.1 0.081 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF494) Pex14_N PF04695.13 KFP16854.1 - 0.052 14.2 3.4 0.075 13.7 1.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NOC3p PF07540.11 KFP16854.1 - 0.079 13.4 0.1 0.31 11.5 0.1 2.0 1 1 1 2 2 2 0 Nucleolar complex-associated protein CUT PF02376.15 KFP16854.1 - 0.086 13.0 1.1 0.26 11.5 0.1 2.3 3 0 0 3 3 2 0 CUT domain YdaS_antitoxin PF15943.5 KFP16854.1 - 0.1 12.5 1.1 0.88 9.5 0.1 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KFP16854.1 - 0.25 11.2 0.2 0.25 11.2 0.2 2.6 3 0 0 3 3 3 0 Homeodomain-like domain DUF4462 PF14692.6 KFP16858.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) PMSR PF01625.21 KFP16860.1 - 4.8e-28 98.3 0.1 5.3e-28 98.1 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Trypsin PF00089.26 KFP16861.1 - 9.3e-47 159.7 0.0 1e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KFP16861.1 - 3.3e-06 27.5 0.0 7.6e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DCX PF03607.17 KFP16863.1 - 1.2e-31 108.6 0.0 5.1e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Doublecortin Sox17_18_mid PF12067.8 KFP16864.1 - 6.7e-20 70.9 6.3 6.7e-20 70.9 6.3 2.2 2 0 0 2 2 2 1 Sox 17/18 central domain HMG_box PF00505.19 KFP16864.1 - 0.0084 16.5 1.1 0.014 15.8 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box TMEM171 PF15471.6 KFP16864.1 - 2.4 7.1 4.4 3.5 6.5 4.4 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 G-patch PF01585.23 KFP16866.1 - 8.3e-17 60.8 3.4 1.6e-16 59.9 3.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP16866.1 - 5.8e-09 35.9 1.4 5.8e-09 35.9 1.4 2.3 3 0 0 3 3 3 1 G-patch domain YcgL PF05166.13 KFP16866.1 - 0.077 13.4 0.1 2.1 8.8 0.1 2.3 2 0 0 2 2 2 0 YcgL domain XK-related PF09815.9 KFP16869.1 - 2.6e-100 335.8 21.3 3e-100 335.6 21.3 1.0 1 0 0 1 1 1 1 XK-related protein ECF_trnsprt PF12822.7 KFP16869.1 - 0.08 13.0 7.9 0.15 12.2 7.9 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Meleagrin PF08189.11 KFP16872.1 - 6e-22 77.1 17.3 7.2e-22 76.8 17.3 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family DIM PF08194.12 KFP16872.1 - 0.036 14.3 0.1 0.07 13.3 0.1 1.5 1 0 0 1 1 1 0 DIM protein Meleagrin PF08189.11 KFP16874.1 - 5.8e-22 77.1 17.3 7.2e-22 76.8 17.3 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family DIM PF08194.12 KFP16874.1 - 0.079 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 DIM protein Myotub-related PF06602.14 KFP16875.1 - 7.1e-103 344.2 0.6 8.3e-103 344.0 0.6 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Hydrolase_6 PF13344.6 KFP16875.1 - 0.025 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Epimerase PF01370.21 KFP16876.1 - 4.8e-22 78.6 0.1 2.6e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP16876.1 - 1.8e-15 57.2 0.0 1e-14 54.7 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFP16876.1 - 1.2e-07 31.1 0.0 2.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFP16876.1 - 1e-06 28.2 0.2 8.6e-06 25.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KFP16876.1 - 1.3e-06 27.6 0.0 2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFP16876.1 - 0.00051 19.3 0.0 0.0048 16.1 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KFP16876.1 - 0.044 13.7 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 KR domain DUF1100 PF06500.11 KFP16876.1 - 0.088 11.6 0.0 0.35 9.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF4462 PF14692.6 KFP16877.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) FAM167 PF11652.8 KFP16878.1 - 1.6e-38 131.0 2.3 3.5e-38 130.0 2.3 1.6 1 0 0 1 1 1 1 FAM167 LURAP PF14854.6 KFP16878.1 - 0.0024 17.8 0.4 0.0044 17.0 0.4 1.4 1 0 0 1 1 1 1 Leucine rich adaptor protein DUF2388 PF09498.10 KFP16878.1 - 0.013 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF4530 PF15039.6 KFP16878.1 - 0.26 11.4 7.2 0.43 10.7 6.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Dapper PF15268.6 KFP16878.1 - 7.4 5.3 7.7 10 4.8 7.7 1.4 1 1 0 1 1 1 0 Dapper Pkinase_Tyr PF07714.17 KFP16879.1 - 2.6e-94 315.3 0.0 3.4e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP16879.1 - 1.9e-46 158.6 0.0 2.7e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP16879.1 - 4.8e-26 90.7 0.1 8.7e-26 89.8 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP16879.1 - 8.1e-15 54.2 0.0 1.9e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP16879.1 - 7.8e-10 38.5 0.0 1.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP16879.1 - 3.6e-08 33.0 0.1 1.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP16879.1 - 0.0081 15.2 0.1 0.012 14.6 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain SH3_3 PF08239.11 KFP16879.1 - 0.014 15.6 0.1 0.038 14.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_16 PF18348.1 KFP16879.1 - 0.039 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Kdo PF06293.14 KFP16879.1 - 0.13 11.6 0.1 0.3 10.4 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family H2TH PF06831.14 KFP16880.1 - 5.2e-12 45.6 0.0 8.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFP16880.1 - 0.00015 22.4 0.0 0.00024 21.7 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 KFP16880.1 - 0.032 14.1 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS SQS_PSY PF00494.19 KFP16881.1 - 2.6e-36 125.5 0.0 3.5e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_C1 PF00112.23 KFP16882.1 - 1.1e-67 228.3 3.5 1.4e-67 228.0 3.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KFP16882.1 - 8.5e-20 70.4 0.6 1.9e-19 69.3 0.6 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KFP16882.1 - 0.12 11.1 2.1 3.7 6.2 0.3 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Defensin_beta PF00711.19 KFP16883.1 - 6.1e-11 42.2 12.5 7.1e-11 41.9 12.5 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta_2 PF13841.6 KFP16883.1 - 0.068 13.7 13.2 0.099 13.1 13.2 1.3 1 0 0 1 1 1 0 Beta defensin Phage_holin_1 PF04531.13 KFP16883.1 - 0.16 12.5 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage holin Defensin_beta PF00711.19 KFP16884.1 - 1.9e-06 27.8 6.4 2.3e-06 27.5 6.4 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta_2 PF13841.6 KFP16884.1 - 3.8e-05 24.1 6.7 4.9e-05 23.7 6.7 1.2 1 0 0 1 1 1 1 Beta defensin m_DGTX_Dc1a_b_c PF17491.2 KFP16884.1 - 0.22 12.2 3.7 0.31 11.7 3.7 1.3 1 1 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Defensin_1 PF00323.19 KFP16884.1 - 1.2 9.8 7.3 5.3 7.7 7.3 2.0 1 1 0 1 1 1 0 Mammalian defensin Defensin_beta PF00711.19 KFP16885.1 - 9.6e-06 25.5 25.3 6e-05 23.0 9.5 2.7 2 1 0 2 2 2 2 Beta defensin Defensin_beta PF00711.19 KFP16887.1 - 6.3e-11 42.1 7.1 7.4e-11 41.9 7.1 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFP16887.1 - 0.016 15.4 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.19 KFP16888.1 - 6e-13 48.6 6.6 6.6e-13 48.4 6.6 1.0 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.19 KFP16889.1 - 6.3e-09 35.7 9.5 7.8e-09 35.4 9.5 1.2 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.19 KFP16890.1 - 1.2e-09 38.0 10.6 1.4e-09 37.8 10.6 1.1 1 0 0 1 1 1 1 Beta defensin DEFB136 PF17333.2 KFP16890.1 - 3.2e-06 27.0 4.5 4.2e-06 26.6 4.5 1.1 1 0 0 1 1 1 1 Beta defensin 136 Defensin_beta PF00711.19 KFP16891.1 - 2.2e-07 30.8 11.4 2.6e-07 30.5 11.4 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.18 KFP16891.1 - 0.046 14.0 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 Defensin propeptide 7tm_4 PF13853.6 KFP16892.1 - 4.8e-47 161.0 7.7 5.6e-47 160.8 7.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP16892.1 - 4.7e-28 98.2 10.9 6.6e-28 97.8 10.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16892.1 - 0.00012 21.6 10.8 0.00019 20.9 10.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP16892.1 - 0.0073 16.0 4.7 0.0073 16.0 4.7 2.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx BAG PF02179.16 KFP16893.1 - 2.6e-09 37.4 2.4 6.4e-09 36.1 2.4 1.7 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KFP16893.1 - 3.2e-08 33.2 0.1 3.2e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family PHTB1_C PF14728.6 KFP16893.1 - 0.0012 18.0 0.9 0.0014 17.8 0.9 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus Ubiquitin_5 PF18037.1 KFP16893.1 - 0.0034 17.7 1.1 0.0083 16.5 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain SesA PF17107.5 KFP16893.1 - 0.0065 16.7 2.8 0.012 15.8 2.8 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Phage_GPO PF05929.11 KFP16893.1 - 0.04 13.5 1.1 0.054 13.1 1.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TRPM_tetra PF16519.5 KFP16893.1 - 0.041 14.0 2.3 4.2 7.6 0.8 3.4 2 1 1 3 3 3 0 Tetramerisation domain of TRPM YPEB PF14620.6 KFP16893.1 - 0.041 13.2 2.8 0.03 13.7 1.4 1.5 2 0 0 2 2 2 0 YpeB sporulation Zwint PF15556.6 KFP16893.1 - 0.06 12.8 6.5 0.11 12.0 3.7 1.9 1 1 1 2 2 2 0 ZW10 interactor DASH_Duo1 PF08651.10 KFP16893.1 - 0.069 12.9 1.8 0.32 10.8 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 PIN_8 PF18476.1 KFP16893.1 - 0.085 12.7 3.9 0.13 12.1 3.9 1.2 1 0 0 1 1 1 0 PIN like domain Ubiquitin_4 PF18036.1 KFP16893.1 - 0.099 12.7 0.4 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2247 PF10004.9 KFP16893.1 - 0.099 12.4 1.2 0.13 12.0 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) MscS_porin PF12795.7 KFP16893.1 - 0.17 11.4 6.8 0.84 9.1 0.4 2.4 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 KFP16893.1 - 0.17 12.1 2.7 0.27 11.4 2.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Uds1 PF15456.6 KFP16893.1 - 0.18 12.0 2.9 0.47 10.6 0.6 2.2 1 1 1 2 2 2 0 Up-regulated During Septation Prefoldin PF02996.17 KFP16893.1 - 0.3 11.0 6.7 0.92 9.4 1.5 2.6 1 1 1 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 KFP16893.1 - 0.41 10.9 11.0 0.48 10.7 7.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.21 KFP16893.1 - 0.49 10.9 7.6 1.4 9.5 3.9 2.6 3 0 0 3 3 3 0 Spectrin repeat FapA PF03961.13 KFP16893.1 - 0.5 8.9 8.9 0.88 8.1 8.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2408 PF10303.9 KFP16893.1 - 0.74 10.4 6.4 5.6 7.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) GrpE PF01025.19 KFP16893.1 - 0.9 9.2 9.1 2 8.0 8.6 1.8 1 1 0 1 1 1 0 GrpE Laminin_II PF06009.12 KFP16893.1 - 1.7 8.7 6.8 1.8 8.6 0.9 2.6 2 1 1 3 3 3 0 Laminin Domain II DASH_Dad2 PF08654.10 KFP16893.1 - 1.7 9.1 7.2 0.36 11.3 1.1 2.6 2 1 1 3 3 2 0 DASH complex subunit Dad2 DUF4140 PF13600.6 KFP16893.1 - 2.4 8.6 5.2 3.3 8.2 1.9 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 KFP16893.1 - 2.5 8.6 5.8 8.3 6.9 2.9 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 KFP16893.1 - 3 8.1 5.7 21 5.5 0.1 2.9 3 1 1 4 4 2 0 Proteins of 100 residues with WXG DUF2205 PF10224.9 KFP16893.1 - 6 6.9 9.4 4.9 7.2 0.5 3.4 4 0 0 4 4 3 0 Short coiled-coil protein DUF1033 PF06279.11 KFP16894.1 - 0.00046 20.3 1.2 0.0011 19.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1033) KH_1 PF00013.29 KFP16895.1 - 6.9e-56 186.0 13.4 3.7e-19 68.3 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFP16895.1 - 1e-16 60.5 6.4 7e-06 25.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFP16895.1 - 2.7e-09 36.8 2.9 0.0032 17.3 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFP16895.1 - 2.8e-07 30.5 6.3 0.075 13.1 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFP16895.1 - 6.1e-05 23.0 0.0 0.012 15.6 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain DUF370 PF04025.12 KFP16895.1 - 0.0074 16.4 1.0 0.34 11.1 0.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF370) MOSC_N PF03476.16 KFP16896.1 - 9.6e-31 106.2 0.0 1.7e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KFP16896.1 - 1.4e-23 83.3 0.0 2.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KFP16896.1 - 3.8e-22 78.8 0.0 8.1e-22 77.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Y_phosphatase PF00102.27 KFP16897.1 - 8.4e-80 267.7 1.2 1.8e-79 266.6 1.2 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 KFP16897.1 - 8.3e-25 87.0 2.3 1.8e-24 85.9 1.4 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain PDZ PF00595.24 KFP16897.1 - 7.7e-21 74.2 0.1 2.2e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 PDZ domain FERM_M PF00373.18 KFP16897.1 - 8.1e-21 74.6 0.2 2.5e-20 73.1 0.2 1.9 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KFP16897.1 - 2.1e-16 59.6 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain PDZ_6 PF17820.1 KFP16897.1 - 8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 KFP16897.1 - 6.8e-05 22.7 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP16897.1 - 0.00056 19.9 0.1 0.0011 19.1 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP16897.1 - 0.0015 18.7 0.2 0.0033 17.5 0.2 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate PDZ_2 PF13180.6 KFP16897.1 - 0.019 15.3 0.0 0.061 13.7 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DOMON PF03351.17 KFP16898.1 - 1.2e-23 83.7 0.1 1.5e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 DOMON domain AI-2E_transport PF01594.16 KFP16899.1 - 1.2e-11 44.4 29.1 3.5e-10 39.6 18.1 3.6 4 1 0 4 4 4 2 AI-2E family transporter Vma12 PF11712.8 KFP16899.1 - 8.3 6.5 6.5 3.1 7.9 2.9 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YL1_C PF08265.11 KFP16900.1 - 4.1e-12 45.6 0.9 7.1e-12 44.9 0.1 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Glycos_transf_2 PF00535.26 KFP16901.1 - 5.4e-39 133.7 0.0 8.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP16901.1 - 1.1e-27 96.8 1.6 1.8e-27 96.1 1.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP16901.1 - 2.9e-08 33.9 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP16901.1 - 1.3e-05 24.7 0.1 2.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP16901.1 - 0.00033 20.2 0.0 0.00095 18.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP16901.1 - 0.0053 17.5 0.1 3.6 8.4 0.0 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like DUF4674 PF15719.5 KFP16903.1 - 2.4e-66 223.5 12.5 2.6e-66 223.3 12.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) Rpr2 PF04032.16 KFP16903.1 - 0.5 10.7 6.0 1.1 9.6 2.4 2.6 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain CREPT PF16566.5 KFP16904.1 - 2e-58 196.7 1.0 2e-58 196.7 1.0 1.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFP16904.1 - 1e-22 80.7 0.4 4.6e-22 78.6 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. PhoU PF01895.19 KFP16904.1 - 0.011 16.1 2.1 0.22 12.0 0.7 2.3 2 0 0 2 2 2 0 PhoU domain DIRP PF06584.13 KFP16904.1 - 0.035 14.3 1.0 0.091 13.0 0.3 1.9 2 0 0 2 2 2 0 DIRP Com_YlbF PF06133.11 KFP16904.1 - 0.064 13.9 1.6 0.27 11.9 0.5 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FH2 PF02181.23 KFP16905.1 - 7.9e-93 311.5 7.6 7.9e-93 311.5 7.6 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain BEN PF10523.9 KFP16906.1 - 8.5e-25 86.8 0.1 3e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 BEN domain NADH_Oxid_Nqo15 PF11497.8 KFP16906.1 - 0.15 12.1 1.1 0.45 10.5 0.2 2.1 1 1 1 2 2 2 0 NADH-quinone oxidoreductase chain 15 NHS PF15273.6 KFP16907.1 - 3.9e-189 630.9 48.6 8.9e-181 603.2 40.0 3.0 2 2 1 3 3 3 2 NHS-like EF-hand_4 PF12763.7 KFP16909.1 - 2.2e-05 24.3 0.0 6.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 KFP16909.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair CHDCT2 PF08074.11 KFP16909.1 - 0.15 12.2 0.8 0.38 10.9 0.8 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CAF1C_H4-bd PF12265.8 KFP16910.1 - 3e-27 94.7 1.2 2.7e-26 91.6 0.4 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFP16910.1 - 1.7e-26 91.9 15.8 3.2e-07 30.9 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP16910.1 - 1.2e-05 25.5 0.7 0.0051 17.1 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP16910.1 - 7.5e-05 22.7 0.2 0.017 15.0 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.12 KFP16910.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Taxilin PF09728.9 KFP16911.1 - 5e-118 393.8 76.1 5.7e-118 393.6 76.1 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HTH_26 PF13443.6 KFP16911.1 - 0.044 14.2 1.3 0.35 11.3 0.0 3.2 3 1 1 4 4 4 0 Cro/C1-type HTH DNA-binding domain STOP PF05217.12 KFP16911.1 - 0.07 13.4 0.5 0.3 11.4 0.5 2.2 1 0 0 1 1 1 0 STOP protein Metallothio_2 PF01439.18 KFP16911.1 - 0.68 10.9 1.6 11 7.0 0.1 2.8 2 0 0 2 2 2 0 Metallothionein APG6_N PF17675.1 KFP16911.1 - 4.1 7.9 73.9 2.7 8.5 25.8 3.9 1 1 2 3 3 3 0 Apg6 coiled-coil region BSD PF03909.17 KFP16912.1 - 1.1e-13 51.0 1.3 1.1e-13 51.0 1.3 3.6 4 1 1 5 5 5 1 BSD domain RlaP PF10127.9 KFP16912.1 - 0.098 12.2 3.6 0.22 11.1 3.6 1.6 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family CTP_synth_N PF06418.14 KFP16913.1 - 5.4e-127 422.6 0.3 6.9e-127 422.2 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFP16913.1 - 1.6e-56 191.1 0.0 2.8e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFP16913.1 - 5.9e-09 36.0 0.0 1.5e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KFP16913.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain 7tm_1 PF00001.21 KFP16915.1 - 7.1e-55 186.2 13.5 8.9e-55 185.8 13.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP16915.1 - 2.4e-10 40.2 12.8 4.6e-10 39.3 12.8 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP16915.1 - 5.9e-10 39.0 9.7 1.1e-09 38.1 9.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP16915.1 - 0.00045 20.0 13.2 0.001 18.9 13.2 1.7 1 1 0 1 1 1 1 Olfactory receptor Clat_adaptor_s PF01217.20 KFP16916.1 - 2.2e-60 202.7 2.2 2.6e-60 202.5 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 KFP16916.1 - 0.002 16.7 0.3 0.0026 16.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) PulA_N1 PF17999.1 KFP16916.1 - 0.07 13.9 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain zf-CCCH PF00642.24 KFP16917.1 - 9.8e-13 47.7 13.0 1.6e-06 27.9 4.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP16917.1 - 3e-06 27.1 13.6 0.0002 21.3 2.3 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFP16917.1 - 7e-06 25.7 12.4 0.00047 19.9 4.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger RRM_1 PF00076.22 KFP16917.1 - 9.2e-05 22.2 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP16917.1 - 0.0057 16.6 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KFP16917.1 - 0.015 16.0 0.3 0.015 16.0 0.3 4.1 3 2 1 4 4 4 0 Torus domain DUF3430 PF11912.8 KFP16917.1 - 0.11 12.5 0.6 0.17 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Collectrin PF16959.5 KFP16918.1 - 7.1e-70 233.7 1.1 1.1e-69 233.1 1.1 1.3 1 0 0 1 1 1 1 Renal amino acid transporter DUF5305 PF17231.2 KFP16918.1 - 0.0084 15.5 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) MscL PF01741.18 KFP16918.1 - 0.011 16.1 0.2 0.02 15.2 0.1 1.5 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL CcmH PF03918.14 KFP16918.1 - 0.031 13.6 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF2140 PF09911.9 KFP16918.1 - 0.045 13.3 0.2 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) EphA2_TM PF14575.6 KFP16918.1 - 0.047 14.6 0.1 0.16 12.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pilin_N PF07790.11 KFP16918.1 - 0.065 14.2 0.1 0.45 11.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal UPF0524 PF15823.5 KFP16918.1 - 0.074 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF4381 PF14316.6 KFP16918.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Chordopox_A13L PF05961.11 KFP16918.1 - 0.096 12.9 0.4 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Saf_2TM PF18303.1 KFP16918.1 - 0.16 11.6 0.9 0.39 10.3 0.5 1.7 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain FeoB_associated PF12669.7 KFP16918.1 - 1.8 9.0 4.4 2.2 8.7 2.0 2.3 2 1 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Pkinase_Tyr PF07714.17 KFP16919.1 - 2.3e-92 309.0 0.0 3.3e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP16919.1 - 2.9e-44 151.4 0.0 4.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 KFP16919.1 - 2e-19 70.1 0.1 6.5e-19 68.4 0.1 2.0 1 0 0 1 1 1 1 PH domain BTK PF00779.19 KFP16919.1 - 6.7e-13 48.2 4.1 1.6e-12 47.0 4.1 1.7 1 0 0 1 1 1 1 BTK motif SH2 PF00017.24 KFP16919.1 - 8e-12 45.1 0.2 2.3e-11 43.6 0.2 1.9 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP16919.1 - 1.6e-07 30.8 0.0 4.8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP16919.1 - 2.2e-05 24.2 0.1 6.9e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP16919.1 - 0.0002 20.4 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain SH3_2 PF07653.17 KFP16919.1 - 0.0006 19.4 0.0 0.0032 17.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain PH_8 PF15409.6 KFP16919.1 - 0.0031 17.7 2.4 0.0089 16.3 1.7 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 KFP16919.1 - 0.0072 16.4 0.5 0.033 14.3 0.2 2.2 2 0 0 2 2 2 1 PH domain SH3_10 PF17902.1 KFP16919.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_4 PF06347.13 KFP16919.1 - 0.013 15.3 0.2 0.051 13.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_3 PF08239.11 KFP16919.1 - 0.034 14.4 0.1 0.086 13.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain PH_11 PF15413.6 KFP16919.1 - 0.53 10.7 4.8 0.26 11.7 1.4 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain PDGF PF00341.17 KFP16920.1 - 1e-22 80.2 9.5 1e-22 80.2 9.5 2.3 2 1 0 2 2 2 1 PDGF/VEGF domain CXCXC PF03128.14 KFP16920.1 - 0.049 14.1 4.3 0.049 14.1 4.3 6.5 6 0 0 6 6 6 0 CXCXC repeat PIGA PF08288.12 KFP16921.1 - 7.7e-24 84.1 2.0 7.7e-24 84.1 2.0 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KFP16921.1 - 7.6e-23 80.9 0.0 1.4e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP16921.1 - 5.2e-21 75.5 0.1 1e-20 74.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFP16921.1 - 7.8e-14 52.0 0.4 1.4e-13 51.2 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KFP16921.1 - 0.0014 19.0 0.1 0.0072 16.7 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Ank_2 PF12796.7 KFP16922.1 - 2.1e-50 169.2 9.5 1.9e-15 57.2 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP16922.1 - 1.1e-33 115.2 7.2 1.9e-09 37.9 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP16922.1 - 9e-31 102.5 1.5 0.0052 17.2 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFP16922.1 - 4.5e-26 90.6 5.9 7.2e-07 29.4 0.1 5.0 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP16922.1 - 1.1e-24 85.7 7.4 0.00096 19.5 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat SOCS_box PF07525.16 KFP16922.1 - 2.9e-11 43.5 4.9 6.1e-11 42.5 4.9 1.6 1 0 0 1 1 1 1 SOCS box DUF2600 PF10776.9 KFP16922.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) DUF1843 PF08898.10 KFP16922.1 - 0.16 12.5 0.1 13 6.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 KFP16923.1 - 1e-33 115.7 8.7 2.5e-12 47.2 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP16923.1 - 9.1e-29 99.5 5.2 1.5e-08 35.0 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP16923.1 - 3.2e-26 88.5 5.7 0.0032 17.9 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFP16923.1 - 3.7e-25 87.2 11.5 0.0012 19.2 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFP16923.1 - 7.6e-19 67.5 7.0 8.8e-05 22.7 0.2 5.4 1 1 3 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP16923.1 - 2.3e-06 27.8 3.4 4.1e-06 27.0 3.4 1.4 1 0 0 1 1 1 1 SOCS box Furin-like_2 PF15913.5 KFP16925.1 - 3.7e-49 165.4 22.2 3.7e-49 165.4 22.2 2.0 2 0 0 2 2 2 1 Furin-like repeat, cysteine-rich TSP_1 PF00090.19 KFP16925.1 - 4.9e-05 23.5 4.3 4.9e-05 23.5 4.3 3.8 3 1 1 4 4 4 1 Thrombospondin type 1 domain NGP1NT PF08153.12 KFP16926.1 - 3.2e-46 156.7 0.3 9e-46 155.2 0.3 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFP16926.1 - 2e-17 63.3 0.4 7.4e-13 48.6 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP16926.1 - 2.2e-05 24.0 0.1 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP16926.1 - 0.00018 21.5 0.0 0.001 19.0 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KFP16926.1 - 0.011 15.2 0.2 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP16926.1 - 0.18 11.3 4.9 1 8.9 0.0 3.6 3 1 1 5 5 5 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFP16926.1 - 0.71 9.9 13.1 0.35 10.9 2.4 4.9 2 1 1 3 3 3 0 Dynamin family FHA PF00498.26 KFP16927.1 - 1.4e-19 70.2 0.0 2.5e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP16927.1 - 1.5e-05 25.2 0.0 0.00062 20.0 0.0 2.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NuA4 PF09340.10 KFP16928.1 - 0.061 13.2 2.4 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 SMYLE_N PF18615.1 KFP16928.1 - 0.31 10.6 2.5 0.38 10.3 2.5 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RNase_Zc3h12a PF11977.8 KFP16929.1 - 7e-55 185.1 0.0 1e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Regnase_1_C PF18561.1 KFP16929.1 - 1.2e-25 89.0 0.1 2.2e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain zf-CCCH_4 PF18044.1 KFP16929.1 - 4.2e-05 23.2 5.5 8.3e-05 22.3 3.5 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFP16929.1 - 0.025 14.5 7.1 0.054 13.4 2.7 3.1 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP16929.1 - 0.032 14.7 6.0 0.088 13.3 6.0 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger FAM220 PF15487.6 KFP16929.1 - 0.32 10.6 1.8 0.52 9.9 1.8 1.3 1 0 0 1 1 1 0 FAM220 family zf_CCCH_4 PF18345.1 KFP16929.1 - 3.6 7.8 10.2 4.3 7.5 1.8 3.2 2 1 1 3 3 3 0 Zinc finger domain ANF_receptor PF01094.28 KFP16930.1 - 7e-72 242.5 0.0 9.3e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP16930.1 - 6.3e-54 181.9 0.1 1e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP16930.1 - 2.6e-46 156.5 0.0 1.1e-45 154.5 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP16930.1 - 1.9e-19 70.0 0.0 4.3e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP16930.1 - 6.9e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Oscp1 PF10188.9 KFP16931.1 - 4.9e-70 235.2 2.2 6.7e-70 234.7 2.2 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 Pkinase PF00069.25 KFP16932.1 - 2.1e-37 128.9 0.0 3.2e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16932.1 - 1.5e-20 73.6 0.0 2.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP16932.1 - 2.9e-05 23.6 1.1 0.00055 19.3 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP16932.1 - 0.00069 18.5 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP16932.1 - 0.0064 15.5 0.7 0.015 14.2 0.7 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP16932.1 - 0.033 13.6 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family THRAP3_BCLAF1 PF15440.6 KFP16933.1 - 3.3e-201 670.8 116.3 3.3e-201 670.8 116.3 2.3 2 0 0 2 2 2 1 THRAP3/BCLAF1 family Ig_3 PF13927.6 KFP16935.1 - 6.7e-29 100.3 0.7 6.3e-16 58.7 0.1 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP16935.1 - 1.3e-27 95.6 0.0 3.7e-15 55.8 0.0 3.3 4 0 0 4 4 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP16935.1 - 7.3e-18 64.7 0.1 2.2e-08 34.3 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP16935.1 - 3.3e-17 62.4 0.1 2.4e-07 30.8 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Kazal_2 PF07648.15 KFP16935.1 - 1.3e-07 31.6 6.3 1.3e-07 31.6 6.3 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KFP16935.1 - 3.9e-07 30.2 2.6 0.064 13.4 0.1 4.3 3 1 0 3 3 3 2 Immunoglobulin V-set domain EF-hand_1 PF00036.32 KFP16935.1 - 7.7e-06 25.1 0.4 2.9e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP16935.1 - 8.4e-06 26.1 3.7 2.7e-05 24.5 3.7 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP16935.1 - 1.2e-05 24.8 0.5 0.0003 20.5 0.2 3.1 2 0 0 2 2 2 1 EF-hand domain Kazal_1 PF00050.21 KFP16935.1 - 5.8e-05 23.0 7.5 8.1e-05 22.6 6.2 2.0 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ig_6 PF18452.1 KFP16935.1 - 0.0028 17.2 0.0 0.61 9.7 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 KFP16935.1 - 0.0052 17.1 0.0 0.46 10.9 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin C1-set domain EF-hand_8 PF13833.6 KFP16935.1 - 0.0069 16.2 1.1 0.015 15.1 0.4 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP16935.1 - 0.02 14.4 0.2 0.069 12.7 0.2 2.0 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.9 KFP16935.1 - 0.038 14.3 0.7 0.097 13.0 0.7 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region C2-set_2 PF08205.12 KFP16935.1 - 0.13 12.3 0.6 3.1 7.9 0.0 2.9 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain DMP1 PF07263.11 KFP16939.1 - 3.5e-12 46.0 43.1 6.8e-12 45.1 43.1 1.5 1 1 0 1 1 1 1 Dentin matrix protein 1 (DMP1) LAP1C PF05609.12 KFP16939.1 - 6.9 5.6 18.5 7.4 5.5 18.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BSP_II PF05432.11 KFP16940.1 - 3e-47 161.8 72.6 1.1e-32 114.0 59.4 2.0 1 1 1 2 2 2 2 Bone sialoprotein II (BSP-II) BAT2_N PF07001.11 KFP16940.1 - 0.005 17.3 10.7 0.005 17.3 10.7 2.1 1 1 1 2 2 2 1 BAT2 N-terminus DUF1387 PF07139.11 KFP16940.1 - 2.3 7.9 9.4 3 7.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) rRNA_processing PF08524.11 KFP16940.1 - 3.6 7.6 12.0 7.4 6.6 12.0 1.5 1 0 0 1 1 1 0 rRNA processing Presenilin PF01080.17 KFP16940.1 - 4.2 6.0 10.0 4.5 5.9 10.0 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KFP16940.1 - 9.4 4.9 11.5 11 4.6 11.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Osteopontin PF00865.18 KFP16941.1 - 8.7e-17 61.5 17.7 5.3e-15 55.7 17.1 2.4 1 1 0 1 1 1 1 Osteopontin FAM76 PF16046.5 KFP16941.1 - 0.08 12.3 0.7 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 FAM76 protein Astro_capsid_p PF12226.8 KFP16941.1 - 3 6.9 8.6 3.7 6.6 8.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ABC2_membrane PF01061.24 KFP16943.1 - 4.6e-34 117.7 25.1 4.6e-34 117.7 25.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFP16943.1 - 3.1e-22 79.6 0.2 7.1e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFP16943.1 - 3.1e-07 30.5 0.0 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP16943.1 - 1.6e-05 24.4 0.1 0.022 14.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFP16943.1 - 0.00036 21.1 0.0 0.00036 21.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KFP16943.1 - 0.0031 17.2 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 KFP16943.1 - 0.0045 16.3 13.1 0.0045 16.3 13.1 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KFP16943.1 - 0.007 16.3 0.3 0.029 14.3 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase PDR_assoc PF08370.11 KFP16943.1 - 0.025 14.3 0.2 0.025 14.3 0.2 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 KFP16943.1 - 0.18 10.9 32.6 0.69 9.0 32.6 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF87 PF01935.17 KFP16943.1 - 0.19 11.8 1.1 0.49 10.5 0.0 2.1 3 0 0 3 3 3 0 Helicase HerA, central domain PLAC8 PF04749.17 KFP16944.1 - 1.2e-13 51.9 20.6 2.4e-13 50.9 20.6 1.5 1 1 0 1 1 1 1 PLAC8 family UbiA PF01040.18 KFP16945.1 - 4.6e-51 173.6 7.8 5.4e-51 173.3 7.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.24 KFP16945.1 - 0.36 10.6 5.9 0.59 9.9 4.2 2.2 1 1 1 2 2 2 0 Fatty acid desaturase Glyco_hydro_79n PF03662.14 KFP16946.1 - 8e-27 94.0 0.0 3.9e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Ribosomal_S18 PF01084.20 KFP16947.1 - 7.1e-23 80.6 0.2 1.9e-22 79.2 0.0 1.7 3 0 0 3 3 3 1 Ribosomal protein S18 Tropomyosin PF00261.20 KFP16948.1 - 0.00051 19.5 2.9 0.00051 19.5 2.9 2.1 2 0 0 2 2 2 1 Tropomyosin DUF2096 PF09869.9 KFP16948.1 - 0.037 14.1 0.8 0.077 13.1 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) LMBR1 PF04791.16 KFP16948.1 - 0.11 11.4 1.7 0.13 11.2 1.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF16 PF01519.16 KFP16948.1 - 0.25 11.9 5.1 0.059 13.9 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KFP16948.1 - 0.3 11.5 2.3 1.1 9.7 2.3 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Lge1 PF11488.8 KFP16948.1 - 1.6 9.0 7.5 0.14 12.4 2.3 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF724 PF05266.14 KFP16948.1 - 5.3 6.8 14.1 0.74 9.6 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PIN_12 PF16289.5 KFP16948.1 - 6.3 7.3 7.3 2.5 8.6 1.7 2.5 3 0 0 3 3 3 0 PIN domain OmpH PF03938.14 KFP16948.1 - 7.9 6.8 8.4 1.4 9.2 2.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Acyltransferase PF01553.21 KFP16949.1 - 2e-10 40.4 0.0 3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 KFP16950.1 - 1.2e-19 70.3 0.1 2.7e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase RlmM_FDX PF18125.1 KFP16950.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 RlmM ferredoxin-like domain CTP_transf_1 PF01148.20 KFP16953.1 - 6.5e-85 285.1 21.0 8e-85 284.8 21.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.13 KFP16953.1 - 9.1 5.6 7.2 9.4 5.6 6.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Beach PF02138.18 KFP16954.1 - 1.8e-126 421.1 0.1 3e-126 420.4 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 KFP16954.1 - 5.4e-18 64.9 12.4 1.3e-17 63.7 12.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 KFP16954.1 - 1e-12 48.0 0.0 2.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFP16954.1 - 9.8e-07 29.4 9.3 0.0038 18.0 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4704 PF15787.5 KFP16954.1 - 1e-06 28.2 3.7 3.3e-06 26.6 0.7 3.2 2 2 1 3 3 3 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 KFP16954.1 - 0.0016 18.6 0.0 0.005 17.0 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 KFP16954.1 - 0.0055 16.0 1.4 0.013 14.8 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) E3_UbLigase_R4 PF13764.6 KFP16954.1 - 0.055 11.6 0.1 0.13 10.4 0.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 PP2C PF00481.21 KFP16955.1 - 4.2e-53 180.6 0.2 5.4e-53 180.2 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP16955.1 - 3e-13 49.9 0.0 8.6e-13 48.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFP16955.1 - 0.079 12.9 0.1 4.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF4704 PF15787.5 KFP16956.1 - 2.6e-106 355.0 5.0 2.6e-106 355.0 5.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 KFP16956.1 - 2.7e-49 167.1 0.8 5.7e-49 166.0 0.8 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Laminin_G_3 PF13385.6 KFP16956.1 - 1.1e-11 45.1 0.0 2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sam68-YY PF16568.5 KFP16957.1 - 1.2e-20 74.0 32.5 2.3e-20 73.1 32.5 1.5 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 KH_1 PF00013.29 KFP16957.1 - 5.1e-08 32.6 0.0 9.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 KH domain DNA_primase_lrg PF04104.14 KFP16958.1 - 1.1e-94 316.8 0.0 2.1e-94 315.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PNRC PF15365.6 KFP16959.1 - 6.2e-07 29.0 6.9 6.2e-07 29.0 6.9 1.6 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif M20_dimer PF07687.14 KFP16960.1 - 7.8e-10 38.6 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFP16960.1 - 0.003 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Semialdhyde_dh PF01118.24 KFP16960.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Neur_chan_LBD PF02931.23 KFP16961.1 - 6e-52 176.2 0.5 9.6e-52 175.6 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP16961.1 - 6e-36 124.7 5.5 3.7e-32 112.3 2.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region UQ_con PF00179.26 KFP16962.1 - 7.3e-18 64.6 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP16962.1 - 0.059 13.7 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KFP16962.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B Gtr1_RagA PF04670.12 KFP16963.1 - 3.4e-73 245.8 0.6 4.9e-73 245.3 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFP16963.1 - 1e-06 28.3 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP16963.1 - 1.4e-05 24.6 0.1 3.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP16963.1 - 2.5e-05 24.5 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP16963.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP16963.1 - 0.0082 16.2 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP16963.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AHD PF17793.1 KFP16964.1 - 1.8e-27 94.9 1.4 3.7e-27 93.9 1.4 1.5 1 0 0 1 1 1 1 ANC1 homology domain (AHD) YEATS PF03366.16 KFP16964.1 - 3.5e-08 33.3 0.0 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFP16964.1 - 0.044 13.9 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Na_Ca_ex PF01699.24 KFP16965.1 - 1.5e-59 200.3 50.4 7.3e-31 107.2 22.6 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Orf78 PF06024.12 KFP16965.1 - 0.42 10.9 6.8 21 5.5 1.3 4.1 3 1 0 3 3 3 0 Orf78 (ac78) Ceramidase PF05875.12 KFP16966.1 - 2.2e-40 138.7 12.0 2.5e-40 138.6 12.0 1.0 1 0 0 1 1 1 1 Ceramidase Ribosomal_S6e PF01092.19 KFP16967.1 - 4.2e-64 214.1 1.5 9.5e-64 213.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e DUF4574 PF15141.6 KFP16967.1 - 1.2 9.0 5.8 2.3 8.2 5.8 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DENN PF02141.21 KFP16968.1 - 9.1e-63 211.6 3.8 1.9e-62 210.5 3.8 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP16968.1 - 8.2e-15 55.3 0.4 3.6e-14 53.3 0.4 2.3 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP16968.1 - 1.2e-12 47.6 2.7 1.2e-12 47.6 2.7 2.2 2 0 0 2 2 2 1 dDENN domain PPR_2 PF13041.6 KFP16968.1 - 3.6e-05 23.9 0.0 0.00087 19.4 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family DUF2464 PF10240.9 KFP16968.1 - 0.00032 20.3 0.0 0.00099 18.7 0.0 1.9 1 0 0 1 1 1 1 Multivesicular body subunit 12 PPR_3 PF13812.6 KFP16968.1 - 0.0052 16.8 0.1 0.14 12.3 0.0 2.4 1 1 1 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KFP16968.1 - 0.026 13.9 0.0 0.092 12.1 0.0 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFP16968.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 PPR repeat Perilipin PF03036.16 KFP16969.1 - 2.3e-169 563.6 18.1 2.6e-169 563.4 18.1 1.0 1 0 0 1 1 1 1 Perilipin family Syntaxin-6_N PF09177.11 KFP16969.1 - 0.00089 19.8 6.0 0.25 11.9 1.0 3.0 1 1 1 2 2 2 2 Syntaxin 6, N-terminal SH3BP5 PF05276.14 KFP16969.1 - 0.022 14.6 1.4 0.022 14.6 1.4 2.5 2 1 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Snapin_Pallidin PF14712.6 KFP16969.1 - 0.062 13.7 5.3 2.2 8.7 3.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin V-SNARE_C PF12352.8 KFP16969.1 - 2.7 8.3 5.4 2 8.8 2.2 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus I-set PF07679.16 KFP16971.1 - 2.4e-42 142.9 0.0 2.5e-12 46.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP16971.1 - 7.7e-38 129.0 0.0 4.1e-12 46.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP16971.1 - 1.3e-28 99.1 0.0 3.2e-09 37.0 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP16971.1 - 1.9e-19 69.6 0.0 8.5e-07 29.1 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain Ig_4 PF16680.5 KFP16971.1 - 1.5e-08 34.7 0.0 0.0087 16.3 0.0 3.5 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP16971.1 - 7.7e-08 32.3 0.7 0.27 11.3 0.1 4.2 3 2 1 4 4 4 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP16971.1 - 1e-07 32.1 0.3 0.0018 18.4 0.0 4.7 3 2 1 4 4 4 1 Immunoglobulin V-set domain TSP_1 PF00090.19 KFP16971.1 - 2.4e-05 24.5 11.2 2.4e-05 24.5 11.2 4.9 4 1 0 4 4 4 3 Thrombospondin type 1 domain Ig_6 PF18452.1 KFP16971.1 - 0.00065 19.2 0.0 7.2 6.3 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 KFP16971.1 - 0.0082 16.1 0.2 3.7 7.5 0.0 3.6 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain TSP_1 PF00090.19 KFP16972.1 - 7.5e-24 83.7 68.5 9e-06 25.8 4.0 7.9 6 2 0 6 6 6 5 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP16972.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 BAR PF03114.18 KFP16973.1 - 7.5e-75 251.7 8.3 8.8e-75 251.4 8.3 1.0 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFP16973.1 - 3.2e-15 55.5 0.3 1.7e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP16973.1 - 1.2e-13 50.5 0.0 2.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP16973.1 - 1.5e-13 50.4 0.1 2.9e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFP16973.1 - 1.5e-08 34.2 4.0 8.2e-08 31.7 2.8 2.0 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP16973.1 - 6.3e-05 22.8 5.3 0.00093 19.0 5.3 2.2 1 1 0 1 1 1 1 BAR domain of APPL family MRF_C1 PF13887.6 KFP16973.1 - 0.027 13.6 0.2 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DNA_pol_B_2 PF03175.13 KFP16973.1 - 0.099 11.5 0.9 0.14 11.0 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Exonuc_VII_L PF02601.15 KFP16973.1 - 1 8.8 4.7 1.6 8.3 4.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FH2 PF02181.23 KFP16973.1 - 1.6 7.7 10.3 0.8 8.8 7.6 1.8 2 1 0 2 2 2 0 Formin Homology 2 Domain Tropomyosin_1 PF12718.7 KFP16974.1 - 0.0039 17.3 21.7 0.0039 17.3 21.7 2.9 1 1 1 2 2 1 1 Tropomyosin like ZapB PF06005.12 KFP16974.1 - 0.0068 16.8 7.6 0.0068 16.8 7.6 4.2 3 1 0 3 3 2 1 Cell division protein ZapB BRE1 PF08647.11 KFP16974.1 - 0.01 15.9 14.9 0.01 15.9 14.9 3.9 1 1 4 5 5 4 0 BRE1 E3 ubiquitin ligase PGA_cap PF09587.10 KFP16974.1 - 0.012 15.1 2.4 0.017 14.6 0.1 2.3 1 1 2 3 3 3 0 Bacterial capsule synthesis protein PGA_cap Fib_alpha PF08702.10 KFP16974.1 - 0.02 15.1 10.7 0.02 15.1 10.7 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KFP16974.1 - 0.045 13.8 9.1 0.48 10.5 3.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRAF_BIRC3_bd PF16673.5 KFP16974.1 - 0.66 9.8 9.0 0.56 10.0 0.4 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Med10 PF09748.9 KFP16974.1 - 0.72 9.8 6.1 0.34 10.9 0.3 3.0 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF2316 PF10078.9 KFP16974.1 - 0.89 9.8 20.1 2 8.7 1.7 4.6 1 1 3 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) IFT57 PF10498.9 KFP16974.1 - 2 7.3 30.0 0.063 12.2 12.8 2.8 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Frataxin_Cyay PF01491.16 KFP16974.1 - 2.7 8.1 10.0 0.13 12.4 0.8 3.1 2 1 1 4 4 4 0 Frataxin-like domain ApoO PF09769.9 KFP16974.1 - 2.8 7.9 5.1 3.2 7.7 0.4 2.5 1 1 1 2 2 2 0 Apolipoprotein O DUF948 PF06103.11 KFP16974.1 - 3.1 8.1 12.1 13 6.2 4.3 3.1 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFP16974.1 - 3.5 7.7 17.3 3.3 7.8 4.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 KFP16974.1 - 3.7 6.0 24.2 4.4 5.7 24.2 1.2 1 0 0 1 1 1 0 Macoilin family COG2 PF06148.11 KFP16974.1 - 3.7 7.6 18.9 0.37 10.9 3.0 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KFP16974.1 - 4.5 6.1 38.0 0.49 9.2 25.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KFP16974.1 - 5.5 7.1 32.4 0.04 14.0 11.5 3.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.9 KFP16974.1 - 6.1 6.2 31.2 0.26 10.6 10.3 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF3037 PF11236.8 KFP16974.1 - 6.8 7.1 10.9 2.6 8.5 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) Syntaxin-6_N PF09177.11 KFP16974.1 - 8.7 7.0 17.5 3.1 8.4 3.0 3.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal zf-C2H2 PF00096.26 KFP16975.1 - 7.9e-11 41.8 32.8 0.0037 17.6 1.8 7.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 KFP16975.1 - 5.2e-08 33.0 18.9 0.0046 17.3 0.1 5.7 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFP16975.1 - 2.7e-07 30.9 35.8 0.0067 17.2 1.1 7.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP16975.1 - 1e-05 25.6 14.7 0.093 13.0 0.6 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP16975.1 - 0.046 13.9 10.0 0.22 11.7 0.3 3.7 3 0 0 3 3 3 0 Aberrant zinc-finger DUF5472 PF17566.2 KFP16975.1 - 0.95 9.5 6.0 37 4.4 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5472) LEDGF PF11467.8 KFP16977.1 - 3.8e-28 97.5 5.5 3.8e-28 97.5 5.5 2.5 3 0 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 KFP16977.1 - 0.0027 18.1 0.0 0.0027 18.1 0.0 4.8 3 1 2 5 5 5 1 PWWP domain Bromo_coat PF01318.18 KFP16977.1 - 0.038 14.1 1.7 0.068 13.2 1.7 1.3 1 0 0 1 1 1 0 Bromovirus coat protein zf-SNAP50_C PF12251.8 KFP16978.1 - 4.7e-76 254.9 3.5 5.9e-76 254.6 3.5 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF3808 PF10300.9 KFP16979.1 - 6.7e-167 556.0 10.3 8.6e-167 555.7 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KFP16979.1 - 8.4e-10 38.8 5.2 0.00012 22.2 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP16979.1 - 3.8e-07 29.7 13.4 0.018 15.1 0.8 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP16979.1 - 4.5e-06 26.3 8.0 0.064 13.1 0.4 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP16979.1 - 0.006 16.5 3.3 0.18 11.9 0.4 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP16979.1 - 0.013 16.1 1.0 0.013 16.1 1.0 6.6 7 2 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP16979.1 - 0.04 14.1 8.9 0.28 11.5 1.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat B1 PF02246.15 KFP16979.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein L b1 domain TPR_19 PF14559.6 KFP16979.1 - 0.59 10.7 10.6 2.7 8.6 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP16979.1 - 0.85 10.3 4.6 69 4.2 0.4 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP16979.1 - 4.6 7.2 7.5 0.88 9.5 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Cadherin_3 PF16184.5 KFP16980.1 - 2e-232 755.4 16.1 1.5e-27 95.8 0.0 13.7 13 1 0 13 13 13 12 Cadherin-like Big_9 PF17963.1 KFP16980.1 - 4.4e-15 56.2 6.2 0.052 14.3 0.0 10.4 11 1 0 11 11 11 4 Bacterial Ig domain Cadherin_4 PF17803.1 KFP16980.1 - 1.2e-14 54.7 0.2 0.02 15.5 0.1 8.5 9 0 0 9 9 9 3 Bacterial cadherin-like domain Lectin_C PF00059.21 KFP16980.1 - 4.8e-12 46.6 2.1 1.2e-11 45.3 2.1 1.8 1 0 0 1 1 1 1 Lectin C-type domain Calx-beta PF03160.14 KFP16980.1 - 1.4e-10 41.2 0.1 4.4e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 Calx-beta domain DAN PF03045.15 KFP16981.1 - 4.1e-29 100.9 8.9 8.2e-29 99.9 8.9 1.5 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP16981.1 - 0.00045 20.5 7.1 0.00069 19.9 7.1 1.2 1 0 0 1 1 1 1 Cystine-knot domain Sclerostin PF05463.11 KFP16981.1 - 0.002 17.8 2.7 0.0065 16.2 2.7 1.7 1 1 0 1 1 1 1 Sclerostin (SOST) VASP_tetra PF08776.11 KFP16981.1 - 0.017 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain DHHC PF01529.20 KFP16982.1 - 2.7e-33 114.9 10.2 2.7e-33 114.9 10.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KFP16982.1 - 0.22 11.4 1.1 0.38 10.7 1.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily CTF_NFI PF00859.18 KFP16983.1 - 2.3e-96 323.2 23.0 5.4e-84 282.6 16.7 2.4 1 1 1 2 2 2 2 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.9 KFP16983.1 - 9.1e-25 86.3 3.1 1.6e-24 85.5 3.1 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.16 KFP16983.1 - 1.7e-11 44.3 0.6 3.3e-11 43.3 0.6 1.5 1 0 0 1 1 1 1 MH1 domain PDZ PF00595.24 KFP16984.1 - 5.5e-165 536.2 63.0 2.7e-16 59.7 0.9 13.4 13 0 0 13 13 13 13 PDZ domain PDZ_6 PF17820.1 KFP16984.1 - 1.2e-81 268.4 34.9 1.2e-07 31.5 0.5 13.0 12 0 0 12 12 12 12 PDZ domain PDZ_2 PF13180.6 KFP16984.1 - 2.7e-51 171.8 36.2 4.7e-05 23.6 0.4 13.0 13 0 0 13 13 13 11 PDZ domain L27_2 PF09045.10 KFP16984.1 - 1e-31 108.7 5.1 2.1e-31 107.6 5.1 1.6 1 0 0 1 1 1 1 L27_2 MPDZ_u10 PF16667.5 KFP16984.1 - 5e-23 81.8 15.7 5e-23 81.8 15.7 3.3 3 0 0 3 3 3 1 Unstructured region 10 on multiple PDZ protein L27_1 PF09058.10 KFP16984.1 - 0.0016 18.4 2.3 0.0024 17.8 1.1 2.0 2 0 0 2 2 2 1 L27_1 PDZ_1 PF12812.7 KFP16984.1 - 0.045 13.8 0.2 26 4.9 0.0 4.1 4 0 0 4 4 4 0 PDZ-like domain LURAP PF14854.6 KFP16985.1 - 1.5e-39 134.6 1.8 1.9e-39 134.3 1.8 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein Tax PF02959.16 KFP16985.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 HTLV Tax WD40 PF00400.32 KFP16987.1 - 9.8e-23 80.0 5.5 9.1e-10 39.0 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_alt PF14077.6 KFP16987.1 - 3.2e-20 71.7 0.5 5.3e-20 71.0 0.5 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif ANAPC4_WD40 PF12894.7 KFP16987.1 - 2.9e-06 27.5 0.0 0.00034 20.9 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP16987.1 - 0.0011 17.7 0.3 0.004 15.9 0.3 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP16987.1 - 0.099 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lig_chan-Glu_bd PF10613.9 KFP16988.1 - 2.5e-30 105.0 0.0 3.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 KFP16988.1 - 1.2e-24 86.9 0.2 1.6e-24 86.4 0.2 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KFP16988.1 - 4.1e-12 46.0 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HalX PF08663.10 KFP16989.1 - 0.016 15.5 0.7 0.023 15.0 0.7 1.3 1 0 0 1 1 1 0 HalX domain DUF4140 PF13600.6 KFP16989.1 - 0.054 13.9 0.3 0.054 13.9 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RhoGAP PF00620.27 KFP16990.1 - 1.9e-28 99.2 0.1 2e-19 69.9 0.1 2.5 2 0 0 2 2 2 2 RhoGAP domain C1_1 PF00130.22 KFP16990.1 - 0.0018 18.1 8.3 0.0043 16.9 8.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SLC12 PF03522.15 KFP16990.1 - 0.25 10.3 6.4 0.48 9.4 6.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 KFP16990.1 - 5.7 7.0 7.5 0.97 9.5 2.8 1.9 2 0 0 2 2 2 0 DDHD domain RNA_pol_Rpb5_C PF01191.19 KFP16991.1 - 4.9e-35 119.2 0.8 7.8e-35 118.6 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFP16991.1 - 2.8e-15 56.7 0.0 5.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Pet100 PF09803.9 KFP16991.1 - 0.86 10.2 3.2 8.3 7.0 1.9 2.6 2 1 0 2 2 2 0 Pet100 Helicase_C_4 PF13871.6 KFP16992.1 - 1.1e-117 392.6 0.1 1.5e-117 392.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue AAA_34 PF13872.6 KFP16992.1 - 3.6e-111 370.9 0.0 6.5e-111 370.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ResIII PF04851.15 KFP16992.1 - 5.9e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFP16992.1 - 0.011 14.5 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP16992.1 - 0.095 13.1 0.0 0.56 10.6 0.0 2.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Pkinase PF00069.25 KFP16993.1 - 2.1e-55 188.0 0.0 3e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP16993.1 - 9e-32 110.4 0.0 4.2e-31 108.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP16993.1 - 1.5e-11 44.2 0.0 2.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP16993.1 - 0.0062 15.4 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP16993.1 - 0.02 14.2 0.2 2.1 7.7 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP16993.1 - 0.12 12.3 0.0 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family LMBR1 PF04791.16 KFP16997.1 - 1e-23 84.1 19.1 3e-22 79.2 19.1 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Spore_YhaL PF14147.6 KFP16997.1 - 5.4 6.8 6.2 31 4.3 0.1 3.5 3 0 0 3 3 3 0 Sporulation protein YhaL 7tm_2 PF00002.24 KFP16999.1 - 4.6e-59 199.7 15.3 7.2e-59 199.0 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFP16999.1 - 3.4e-35 121.4 0.2 5.3e-35 120.8 0.2 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain TSP_1 PF00090.19 KFP16999.1 - 7.9e-29 99.6 55.6 1.2e-12 47.9 10.7 4.2 4 0 0 4 4 4 3 Thrombospondin type 1 domain GPS PF01825.21 KFP16999.1 - 4.5e-14 52.7 3.1 4.5e-14 52.7 3.1 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFP16999.1 - 3.4e-07 30.5 0.4 3.4e-07 30.5 0.4 3.2 3 0 0 3 3 3 1 Hormone receptor domain EGF PF00008.27 KFP17010.1 - 3.9e-26 91.0 55.0 1.7e-07 31.4 5.2 5.4 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.7 KFP17010.1 - 9.2e-14 51.5 59.0 3.8e-05 24.1 3.8 6.9 7 1 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 KFP17010.1 - 3.9e-09 36.7 62.7 9.1e-05 22.7 4.1 5.6 5 1 0 5 5 5 4 EGF-like domain EGF_CA PF07645.15 KFP17010.1 - 2.1e-07 31.0 56.0 0.053 13.7 0.0 5.4 3 2 2 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.7 KFP17010.1 - 1.9e-06 28.0 46.1 0.0026 17.9 5.1 5.3 3 1 2 5 5 5 4 EGF domain Laminin_EGF PF00053.24 KFP17010.1 - 0.00012 22.1 46.1 0.48 10.6 7.4 4.5 1 1 3 4 4 4 3 Laminin EGF domain cEGF PF12662.7 KFP17010.1 - 0.0013 18.7 0.2 0.0013 18.7 0.2 4.9 5 0 0 5 5 5 2 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 KFP17010.1 - 0.063 13.6 37.4 0.082 13.2 5.6 4.5 4 0 0 4 4 4 0 Pvs28 EGF domain FXa_inhibition PF14670.6 KFP17010.1 - 0.93 9.8 50.5 1.4 9.3 5.4 5.4 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP17012.1 - 1.6e-92 303.2 200.5 1.6e-09 37.9 9.3 15.3 15 0 0 15 15 15 14 EGF-like domain hEGF PF12661.7 KFP17012.1 - 2.4e-68 224.7 180.6 1.5e-06 28.6 1.4 17.3 17 0 0 17 17 17 14 Human growth factor-like EGF EGF_CA PF07645.15 KFP17012.1 - 8.7e-40 134.7 208.1 1.8e-07 31.2 5.9 14.7 14 1 0 14 14 14 14 Calcium-binding EGF domain EGF_2 PF07974.13 KFP17012.1 - 2.9e-20 72.3 213.4 0.00063 20.1 9.5 14.6 14 0 0 14 14 14 11 EGF-like domain EGF_3 PF12947.7 KFP17012.1 - 4.2e-07 30.1 175.5 0.01 16.0 5.1 15.6 11 2 3 14 14 14 8 EGF domain Laminin_EGF PF00053.24 KFP17012.1 - 5.7e-06 26.4 170.9 1.7 8.9 6.0 14.4 4 2 10 14 14 14 8 Laminin EGF domain EGF_MSP1_1 PF12946.7 KFP17012.1 - 0.0045 17.0 4.8 0.0045 17.0 4.8 14.5 14 0 0 14 14 14 5 MSP1 EGF domain 1 cEGF PF12662.7 KFP17012.1 - 0.019 14.9 1.9 0.019 14.9 1.9 18.0 17 5 1 18 18 18 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP17012.1 - 3.6 7.9 189.4 0.18 12.1 6.2 15.6 9 4 6 15 15 15 0 Coagulation Factor Xa inhibitory site RVT_1 PF00078.27 KFP17014.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP17014.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Laminin_G_2 PF02210.24 KFP17015.1 - 1.9e-23 83.4 1.6 1.5e-19 70.8 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP17015.1 - 1.6e-20 73.7 0.2 7.5e-17 61.8 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP17015.1 - 2.5e-19 69.2 51.0 3.4e-05 24.1 7.1 4.7 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 KFP17015.1 - 1.6e-06 28.5 43.7 0.018 15.7 3.0 5.7 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_2 PF07974.13 KFP17015.1 - 0.0074 16.6 56.2 0.049 14.0 11.3 5.0 4 1 0 4 4 4 3 EGF-like domain Csm4_C PF17953.1 KFP17015.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain FXa_inhibition PF14670.6 KFP17015.1 - 1.9 8.9 41.8 0.72 10.2 5.9 4.9 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site Laminin_G_2 PF02210.24 KFP17016.1 - 8.7e-36 123.3 0.8 7.6e-17 62.1 0.2 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP17016.1 - 1.1e-32 112.9 0.2 3.7e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KFP17016.1 - 2.4e-07 30.9 15.6 0.0005 20.3 6.3 3.2 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFP17016.1 - 0.0043 17.6 4.7 0.0043 17.6 4.7 5.3 7 0 0 7 7 7 2 Human growth factor-like EGF FXa_inhibition PF14670.6 KFP17016.1 - 0.02 15.1 20.8 0.021 15.1 4.5 2.7 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 KFP17016.1 - 0.033 14.6 25.1 0.034 14.5 11.5 3.0 2 1 0 2 2 2 0 EGF-like domain Laminin_G_3 PF13385.6 KFP17016.1 - 0.059 13.5 0.2 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily EGF_3 PF12947.7 KFP17016.1 - 1.2 9.4 16.1 1.1 9.5 2.2 3.0 2 0 0 2 2 2 0 EGF domain TFIIS_M PF07500.14 KFP17017.1 - 2e-31 108.8 3.6 2e-31 108.8 3.6 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KFP17017.1 - 1.8e-28 99.4 0.0 8.3e-28 97.2 0.0 2.2 2 0 0 2 2 2 1 SPOC domain PHD PF00628.29 KFP17017.1 - 5e-09 35.9 10.3 5e-09 35.9 10.3 2.1 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KFP17017.1 - 0.058 13.6 5.0 0.26 11.5 5.0 2.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP17017.1 - 1.9 8.8 9.1 3.4 8.0 5.9 3.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Y_phosphatase PF00102.27 KFP17018.1 - 2.3e-08 33.9 0.0 1.1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP17018.1 - 1e-07 31.8 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gln-synt_C PF00120.24 KFP17020.1 - 1.4e-74 251.2 0.0 2.2e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFP17020.1 - 4.5e-07 29.5 0.5 6.8e-06 25.7 0.2 2.8 2 1 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 KFP17020.1 - 1.6e-05 24.7 0.0 4.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain BRO1 PF03097.18 KFP17029.1 - 2.8e-95 319.4 0.1 4.3e-95 318.8 0.1 1.2 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 KFP17029.1 - 9.6e-20 70.5 5.4 2.5e-19 69.2 5.4 1.8 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.24 KFP17029.1 - 2.5e-13 50.2 0.0 4.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP17029.1 - 1.3e-12 47.3 0.1 2.6e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP17029.1 - 8.1e-06 26.1 0.0 2.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 PDZ domain FAM83 PF07894.12 KFP17029.1 - 0.0032 17.1 1.7 0.004 16.7 0.1 1.9 2 1 0 2 2 2 1 FAM83 A-H Tricorn_PDZ PF14685.6 KFP17029.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Uds1 PF15456.6 KFP17029.1 - 0.27 11.4 4.5 0.69 10.1 4.5 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Topoisom_I PF01028.20 KFP17030.1 - 8.1e-103 342.7 9.2 8.1e-103 342.7 9.2 2.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFP17030.1 - 1.2e-100 335.4 4.5 1.2e-100 335.4 4.5 3.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFP17030.1 - 6e-35 119.0 0.4 3e-34 116.8 0.4 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF641 PF04859.12 KFP17030.1 - 0.023 15.0 4.9 0.023 15.0 4.9 4.0 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Allexi_40kDa PF05549.11 KFP17030.1 - 3.8 6.9 7.6 5.9 6.3 3.6 2.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein UPAR_LY6 PF00021.21 KFP17031.1 - 3.9e-07 30.7 13.9 1.1e-06 29.3 13.9 1.7 1 1 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP17031.1 - 9.8e-06 25.7 21.4 2.4e-05 24.5 20.5 2.0 1 1 1 2 2 2 1 Snake toxin and toxin-like protein Toxin_TOLIP PF00087.21 KFP17032.1 - 4.1e-11 43.0 18.1 5.3e-11 42.6 18.1 1.2 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFP17032.1 - 2.1e-09 37.9 17.3 2.6e-09 37.7 17.3 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain UPAR_LY6 PF00021.21 KFP17033.1 - 7.3e-12 45.8 13.0 1.2e-11 45.2 13.0 1.3 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP17033.1 - 1.5e-11 44.4 13.1 1.5e-11 44.4 13.1 1.4 2 0 0 2 2 2 1 Snake toxin and toxin-like protein UPAR_LY6_2 PF16975.5 KFP17033.1 - 0.092 13.0 13.8 0.24 11.6 13.8 1.6 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6 PF00021.21 KFP17034.1 - 1.3e-15 57.8 10.3 1.6e-15 57.6 10.3 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP17034.1 - 1.4e-09 38.0 9.3 1.7e-09 37.7 9.3 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6_2 PF16975.5 KFP17034.1 - 0.068 13.4 7.6 0.13 12.4 7.6 1.5 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6 PF00021.21 KFP17035.1 - 7.1e-07 29.8 13.2 9.6e-07 29.4 13.2 1.2 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP17035.1 - 0.00078 19.7 13.4 0.0012 19.1 13.4 1.3 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KFP17036.1 - 0.00062 20.4 13.1 0.00079 20.1 13.1 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP17036.1 - 0.002 18.4 13.0 0.0025 18.0 13.0 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein UPAR_LY6_2 PF16975.5 KFP17036.1 - 0.017 15.3 9.0 0.024 14.8 9.0 1.3 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6 PF00021.21 KFP17037.1 - 1.6e-07 31.9 18.9 2e-07 31.6 18.9 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_TOLIP PF00087.21 KFP17037.1 - 8e-05 22.8 16.3 0.0001 22.5 16.3 1.1 1 0 0 1 1 1 1 Snake toxin and toxin-like protein DUF4345 PF14248.6 KFP17037.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Arc_C PF18162.1 KFP17038.1 - 6.9e-47 157.2 1.2 1.9e-46 155.8 1.2 1.8 1 0 0 1 1 1 1 Arc C-lobe Retrotrans_gag PF03732.17 KFP17038.1 - 0.001 19.3 2.1 0.0021 18.3 0.5 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2120 PF09893.9 KFP17038.1 - 0.0061 16.7 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2120) DUF842 PF05811.13 KFP17038.1 - 0.009 15.7 0.3 0.043 13.5 0.3 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF842) THOC7 PF05615.13 KFP17038.1 - 0.021 15.1 0.4 0.038 14.3 0.4 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 KxDL PF10241.9 KFP17038.1 - 0.029 14.6 1.3 6.3 7.2 0.1 2.9 4 0 0 4 4 4 0 Uncharacterized conserved protein FH2 PF02181.23 KFP17038.1 - 0.033 13.3 0.5 0.064 12.4 0.5 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain SYCE1 PF15233.6 KFP17038.1 - 0.15 12.2 5.3 0.59 10.2 0.2 2.7 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 ThiD2 PF17792.1 KFP17038.1 - 0.18 12.3 1.1 0.37 11.3 1.1 1.5 1 0 0 1 1 1 0 ThiD2 family DDE_Tnp_ISL3 PF01610.17 KFP17038.1 - 0.39 10.4 6.0 9 5.9 2.4 2.7 3 0 0 3 3 3 0 Transposase Yae1_N PF09811.9 KFP17039.1 - 0.00016 21.3 42.7 0.03 14.0 2.0 5.6 3 1 2 5 5 5 4 Essential protein Yae1, N terminal Frtz PF11768.8 KFP17040.1 - 0.033 12.5 0.0 0.08 11.3 0.0 1.6 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz cwf18 PF08315.12 KFP17041.1 - 2.8e-32 112.2 10.3 3.4e-32 112.0 10.3 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Spore_III_AB PF09548.10 KFP17041.1 - 0.025 14.7 0.8 0.029 14.5 0.8 1.2 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Arg_tRNA_synt_N PF03485.16 KFP17041.1 - 0.033 14.8 1.0 0.048 14.2 1.0 1.3 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain 7tm_2 PF00002.24 KFP17043.1 - 1.8e-92 309.1 13.0 2.2e-92 308.8 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP17043.1 - 2.1e-19 69.6 2.9 3.9e-19 68.7 2.9 1.5 1 0 0 1 1 1 1 Hormone receptor domain EF-hand_6 PF13405.6 KFP17045.1 - 1.2e-09 37.3 0.1 0.0086 15.9 0.0 4.3 5 1 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFP17045.1 - 1.4e-07 30.5 0.7 0.015 14.8 0.0 4.8 6 1 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 KFP17045.1 - 0.00018 21.9 0.1 0.0039 17.6 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP17045.1 - 0.006 16.4 3.4 1.6 8.6 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair DUF2267 PF10025.9 KFP17045.1 - 0.018 15.3 0.2 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DED PF01335.21 KFP17045.1 - 0.14 12.5 0.1 1 9.7 0.0 2.3 3 0 0 3 3 3 0 Death effector domain UPF0154 PF03672.13 KFP17045.1 - 0.14 12.2 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TMIE PF16038.5 KFP17047.1 - 5.3e-35 119.1 0.6 6.4e-35 118.9 0.6 1.1 1 0 0 1 1 1 1 TMIE protein Shisa PF13908.6 KFP17047.1 - 0.021 15.0 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RCR PF12273.8 KFP17047.1 - 0.044 14.5 0.0 0.068 13.8 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LST1 PF05083.13 KFP17047.1 - 0.05 13.9 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 LST-1 protein EphA2_TM PF14575.6 KFP17047.1 - 0.11 13.4 0.5 0.15 13.0 0.5 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 KFP17047.1 - 0.18 11.7 0.8 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator MORN PF02493.20 KFP17048.1 - 4.2e-21 73.5 38.3 1.2e-06 28.0 5.0 8.9 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.18 KFP17048.1 - 3.4e-20 72.2 0.1 7.7e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Antimicrobial_6 PF08036.11 KFP17048.1 - 0.22 11.6 2.7 0.5 10.5 2.7 1.6 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide Cupin_8 PF13621.6 KFP17050.1 - 2.9e-21 76.4 2.9 4.2e-21 75.8 2.9 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KFP17050.1 - 3.6e-20 72.5 0.3 1.2e-19 70.8 0.2 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFP17050.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein GRAM PF02893.20 KFP17052.1 - 0.00018 21.4 0.1 0.00053 19.9 0.1 1.8 2 0 0 2 2 2 1 GRAM domain DUF5089 PF17002.5 KFP17052.1 - 0.016 15.1 9.6 2.4 8.0 7.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFP17052.1 - 0.35 11.2 3.0 7.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus KxDL PF10241.9 KFP17052.1 - 1.1 9.6 5.5 1.7 9.0 2.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF4462 PF14692.6 KFP17059.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Guanylate_kin PF00625.21 KFP17061.1 - 5e-69 231.6 0.0 5.8e-69 231.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KFP17061.1 - 5.4e-07 30.1 0.4 2e-06 28.3 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFP17061.1 - 2.1e-05 25.1 0.1 4.5e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFP17061.1 - 2.3e-05 24.5 0.1 6.4e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFP17061.1 - 4.9e-05 23.9 0.0 0.00011 22.7 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KFP17061.1 - 0.00032 20.9 0.2 0.0018 18.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFP17061.1 - 0.00034 20.6 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFP17061.1 - 0.00072 19.9 0.1 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFP17061.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 KFP17061.1 - 0.0019 18.2 0.1 0.0058 16.7 0.0 2.0 1 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KFP17061.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 KFP17061.1 - 0.0056 16.3 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KFP17061.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 KFP17061.1 - 0.0081 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFP17061.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFP17061.1 - 0.015 15.8 1.2 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFP17061.1 - 0.015 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFP17061.1 - 0.017 15.6 3.1 0.05 14.0 1.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP17061.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KFP17061.1 - 0.018 15.5 0.5 0.04 14.3 0.0 1.9 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFP17061.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 KFP17061.1 - 0.025 14.4 0.5 0.59 10.0 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase KAP_NTPase PF07693.14 KFP17061.1 - 0.039 13.2 0.0 0.04 13.1 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 KFP17061.1 - 0.04 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KFP17061.1 - 0.041 13.1 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KFP17061.1 - 0.046 13.6 1.2 0.19 11.6 1.2 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KFP17061.1 - 0.053 13.2 0.2 0.22 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KFP17061.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KFP17061.1 - 0.073 13.1 0.8 0.33 10.9 0.0 2.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3734 PF12536.8 KFP17061.1 - 0.097 13.0 0.2 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Patatin phospholipase TsaE PF02367.17 KFP17061.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Connexin PF00029.19 KFP17062.1 - 5.1e-109 363.5 4.4 5.1e-109 363.5 4.4 1.4 2 0 0 2 2 2 1 Connexin Apc13p PF05839.11 KFP17062.1 - 0.19 11.9 1.1 0.51 10.6 1.1 1.6 1 0 0 1 1 1 0 Apc13p protein Connexin40_C PF16791.5 KFP17062.1 - 8.2 7.7 10.9 1 10.7 5.3 2.4 2 1 0 2 2 2 0 Connexin 40 C-terminal domain Ribosomal_S17_N PF16205.5 KFP17063.1 - 1.4e-35 121.5 0.7 1.4e-35 121.5 0.7 1.8 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFP17063.1 - 9.4e-29 99.3 1.6 1.4e-28 98.7 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.11 KFP17063.1 - 0.1 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF UL21a PF17636.2 KFP17063.1 - 0.12 12.4 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Viral Unique Long protein 21a UDPGT PF00201.18 KFP17064.1 - 2.2e-32 112.5 0.0 2.5e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Imm39 PF15568.6 KFP17064.1 - 0.0013 18.9 0.1 0.0024 18.0 0.1 1.3 1 0 0 1 1 1 1 Immunity protein 39 Glyco_transf_4 PF13439.6 KFP17064.1 - 0.024 14.6 0.0 1.6 8.7 0.0 3.0 1 1 1 2 2 2 0 Glycosyltransferase Family 4 BAR_3 PF16746.5 KFP17065.1 - 2.6e-56 191.0 19.3 3.8e-56 190.5 19.3 1.3 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 KFP17065.1 - 4.4e-41 140.2 0.1 1.8e-40 138.2 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP17065.1 - 3.5e-08 33.9 0.1 9.1e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 PH domain Yip1 PF04893.17 KFP17066.1 - 2.9e-18 66.2 12.8 2.9e-18 66.2 12.8 1.7 1 1 1 2 2 2 1 Yip1 domain Ribosomal_L16 PF00252.18 KFP17067.1 - 3.3e-21 75.7 0.0 4.6e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-H2C2_2 PF13465.6 KFP17068.1 - 2.2e-13 49.9 7.7 2.5e-06 27.7 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP17068.1 - 2.7e-05 24.4 4.6 2.7e-05 24.4 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17068.1 - 0.0029 18.3 4.2 0.0029 18.3 4.2 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger F5_F8_type_C PF00754.25 KFP17069.1 - 2.9e-11 43.6 0.0 3.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Histone PF00125.24 KFP17070.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFP17070.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KFP17070.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KFP17070.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFP17070.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFP17070.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KFP17071.1 - 4.6e-26 91.7 0.3 5.6e-26 91.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP17071.1 - 9.5e-07 29.0 1.0 1.8e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP17071.1 - 0.0034 17.8 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFP17071.1 - 0.0038 17.3 0.3 0.0045 17.0 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein adh_short PF00106.25 KFP17072.1 - 9.4e-20 70.9 0.0 6.6e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP17072.1 - 6.8e-10 38.9 0.0 4.7e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KFP17072.1 - 0.025 14.0 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase zf-BED PF02892.15 KFP17074.1 - 5.1e-16 58.4 1.0 1.3e-15 57.1 1.0 1.8 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 KFP17074.1 - 2e-14 53.1 0.1 6.3e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KFP17074.1 - 9.4e-05 22.7 1.7 0.00032 21.0 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) CD99L2 PF12301.8 KFP17076.1 - 1.6e-17 64.3 0.6 1.7e-17 64.2 0.6 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 Glycophorin_A PF01102.18 KFP17076.1 - 0.094 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A CD99L2 PF12301.8 KFP17077.1 - 3.3e-13 50.3 0.6 2.9e-12 47.2 0.6 2.2 1 1 0 1 1 1 1 CD99 antigen like protein 2 Glyco_transf_8 PF01501.20 KFP17078.1 - 2.6e-20 73.0 0.0 6.1e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KFP17078.1 - 0.0025 17.8 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KFP17078.1 - 0.0028 17.1 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Sulfatase_C PF14707.6 KFP17079.1 - 4e-48 163.2 0.1 7e-48 162.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Sulfatase PF00884.23 KFP17079.1 - 2.3e-45 155.3 0.0 3.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP17079.1 - 9.8e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFP17079.1 - 0.086 11.4 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase PF00884.23 KFP17080.1 - 2.6e-84 283.3 0.0 3.3e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP17080.1 - 8.7e-50 168.6 0.0 1.3e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP17080.1 - 2.5e-09 37.2 0.2 0.00051 19.7 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFP17080.1 - 0.22 11.8 0.0 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Sulfatase PF00884.23 KFP17082.1 - 3.6e-85 286.1 0.0 4.7e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP17082.1 - 2.1e-49 167.4 0.1 3.3e-49 166.7 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP17082.1 - 1.7e-10 41.1 0.0 0.00026 20.7 0.0 2.4 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFP17082.1 - 0.2 10.3 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Pkinase PF00069.25 KFP17084.1 - 9.7e-67 225.1 0.0 1.1e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17084.1 - 3.1e-33 115.1 0.0 3.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP17084.1 - 1.1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP17084.1 - 0.0048 16.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP17084.1 - 0.016 14.1 0.2 0.022 13.7 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP17084.1 - 0.043 12.6 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CagZ PF09053.10 KFP17084.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.6 2 0 0 2 2 2 0 CagZ RVT_1 PF00078.27 KFP17088.1 - 0.00052 19.6 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COesterase PF00135.28 KFP17094.1 - 2.2e-198 660.3 0.0 2.8e-198 660.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFP17094.1 - 3.5e-07 30.3 0.2 2.3e-06 27.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SCF PF02404.15 KFP17094.1 - 0.13 11.6 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Stem cell factor HAD_2 PF13419.6 KFP17097.1 - 3.6e-15 56.5 0.0 4.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP17097.1 - 6.1e-10 39.7 0.0 7.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFP17097.1 - 0.00058 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NaeI PF09126.10 KFP17097.1 - 0.046 12.9 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Hydrolase_6 PF13344.6 KFP17097.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sulfatase PF00884.23 KFP17099.1 - 3.5e-91 305.8 0.0 4.3e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KFP17099.1 - 1.1e-43 148.9 0.5 2e-43 148.1 0.5 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KFP17099.1 - 1.2e-07 31.7 0.1 0.00037 20.2 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2101 PF09874.9 KFP17099.1 - 0.13 12.0 2.6 0.22 11.2 2.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Patatin PF01734.22 KFP17102.1 - 3.8e-16 59.9 1.2 1.3e-14 54.9 1.2 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase V-set PF07686.17 KFP17106.1 - 1.1e-12 48.1 0.0 1.4e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP17106.1 - 0.0026 18.3 0.1 0.0077 16.8 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP17106.1 - 0.031 14.4 0.5 0.42 10.8 0.5 2.1 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP17107.1 - 7.3e-11 42.2 0.0 7.9e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.17 KFP17108.1 - 3.2e-12 46.6 0.0 3.8e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP17108.1 - 0.049 14.2 0.0 0.094 13.3 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KFP17109.1 - 1.4e-08 34.9 0.0 1.5e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.17 KFP17110.1 - 4.3e-10 39.7 0.0 4.6e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain V-set PF07686.17 KFP17111.1 - 2.3e-14 53.5 0.0 2.8e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP17111.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP17111.1 - 0.011 15.9 0.3 0.21 11.8 0.3 2.4 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP17111.1 - 0.073 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.17 KFP17112.1 - 1.6e-10 41.1 0.0 1.7e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain GST_C_2 PF13410.6 KFP17113.1 - 6.2e-06 26.1 0.0 6.6e-06 26.1 0.0 1.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP17113.1 - 0.00056 20.1 0.0 0.00064 19.9 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BAH PF01426.18 KFP17114.1 - 2.7e-43 146.7 0.0 7.3e-22 77.5 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KFP17114.1 - 3.2e-28 98.6 0.2 1.1e-27 96.8 0.0 2.1 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain zf-CXXC PF02008.20 KFP17114.1 - 2.8e-15 56.0 21.2 7.8e-15 54.6 21.2 1.8 1 0 0 1 1 1 1 CXXC zinc finger domain DUF2284 PF10050.9 KFP17114.1 - 0.0016 18.2 2.7 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Predicted metal-binding protein (DUF2284) DNA_methylase PF00145.17 KFP17115.1 - 2.9e-33 115.6 0.0 3.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Brix PF04427.18 KFP17116.1 - 6.4e-17 62.3 1.0 7.4e-17 62.1 1.0 1.1 1 0 0 1 1 1 1 Brix domain DUF4046 PF13255.6 KFP17116.1 - 0.098 13.2 0.1 5.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4046) Collagen PF01391.18 KFP17117.1 - 5.8e-143 464.8 619.6 4.4e-09 36.0 31.3 21.5 4 2 12 16 16 16 8 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFP17117.1 - 2.2e-62 210.4 0.0 2.8e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KFP17117.1 - 0.0037 17.8 0.0 0.0061 17.1 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFP17117.1 - 0.034 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily UCH PF00443.29 KFP17118.1 - 1.8e-44 152.2 0.0 2.7e-44 151.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP17118.1 - 2.3e-12 47.2 0.1 7.2e-06 25.8 0.3 2.3 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_1 PF00561.20 KFP17120.1 - 3.5e-21 76.0 0.0 1.5e-20 74.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP17120.1 - 6.7e-17 62.8 0.0 8.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP17120.1 - 2.6e-12 46.5 0.0 3.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFP17120.1 - 0.002 16.9 0.0 0.0063 15.2 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.13 KFP17120.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFP17120.1 - 0.085 12.6 0.0 13 5.5 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase LSPR PF06049.12 KFP17120.1 - 0.097 12.6 0.5 0.52 10.4 0.1 2.4 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat DUF1071 PF06378.11 KFP17120.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Anoctamin PF04547.12 KFP17121.1 - 2.7e-124 415.4 23.2 3.2e-124 415.2 23.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF898 PF05987.13 KFP17121.1 - 0.34 9.9 8.2 0.022 13.8 1.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Pkinase PF00069.25 KFP17122.1 - 1.8e-74 250.5 0.0 3.1e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17122.1 - 7.4e-42 143.4 0.0 1.1e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP17122.1 - 7.5e-10 38.6 0.0 4.9e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP17122.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF563 PF04577.14 KFP17124.1 - 7.6e-21 75.2 0.1 1.6e-20 74.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ribosomal_L14e PF01929.17 KFP17125.1 - 8.9e-31 106.2 8.0 8.9e-31 106.2 8.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 KFP17125.1 - 0.0046 16.9 0.2 0.0079 16.1 0.2 1.4 1 0 0 1 1 1 1 KOW motif DRY_EERY PF09750.9 KFP17125.1 - 0.17 12.1 8.8 0.23 11.7 8.8 1.2 1 0 0 1 1 1 0 Alternative splicing regulator AAA_11 PF13086.6 KFP17125.1 - 0.34 10.7 9.2 0.42 10.4 9.2 1.1 1 0 0 1 1 1 0 AAA domain AIG2_2 PF13772.6 KFP17126.1 - 4.2e-30 104.0 0.0 5.6e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KFP17126.1 - 3.7e-06 27.5 0.0 6.6e-06 26.7 0.0 1.4 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like NACHT PF05729.12 KFP17127.1 - 2.5e-36 125.1 0.0 5.9e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KFP17127.1 - 4.1e-21 75.9 2.6 1.5e-20 74.1 2.6 2.0 1 0 0 1 1 1 1 NLRC4 helical domain HD2 LRR_6 PF13516.6 KFP17127.1 - 2e-18 64.8 4.7 0.015 15.3 0.0 8.8 8 0 0 8 8 8 4 Leucine Rich repeat CARD PF00619.21 KFP17127.1 - 6.6e-15 54.9 0.5 1e-13 51.1 0.1 3.0 3 0 0 3 3 3 1 Caspase recruitment domain NOD2_WH PF17779.1 KFP17127.1 - 2.4e-13 50.2 5.2 2.5e-12 46.9 0.6 3.8 3 0 0 3 3 3 1 NOD2 winged helix domain LRR_4 PF12799.7 KFP17127.1 - 3.4e-05 24.1 2.6 2.3 8.8 0.0 5.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) AAA_16 PF13191.6 KFP17127.1 - 0.001 19.5 0.0 0.0034 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain SpoU_sub_bind PF08032.12 KFP17127.1 - 0.0015 18.8 2.1 2.9 8.2 0.0 4.2 2 1 3 5 5 5 2 RNA 2'-O ribose methyltransferase substrate binding PIF1 PF05970.14 KFP17127.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 KFP17127.1 - 0.078 13.4 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF4581 PF15167.6 KFP17129.1 - 3.1e-49 166.4 0.2 3.5e-49 166.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Toxin_27 PF08099.11 KFP17129.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Scorpion calcine family EAF PF09816.9 KFP17130.1 - 2.3e-16 60.1 0.0 5.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Methyltransf_12 PF08242.12 KFP17132.1 - 1.4e-17 64.2 0.1 1.1e-16 61.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP17132.1 - 9.6e-15 55.1 0.0 2.3e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP17132.1 - 8.1e-14 51.8 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP17132.1 - 2.1e-11 44.3 0.1 5.4e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP17132.1 - 1.5e-09 37.9 0.1 2.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFP17132.1 - 8.9e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KFP17132.1 - 0.00039 19.8 0.0 0.00069 19.0 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFP17132.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KFP17132.1 - 0.039 13.5 0.4 6 6.3 0.1 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain SH3BP5 PF05276.14 KFP17133.1 - 1.3e-76 257.4 20.6 1.9e-76 256.9 20.6 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF812 PF05667.11 KFP17133.1 - 0.074 11.9 14.1 0.11 11.4 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KFP17133.1 - 0.22 11.0 12.2 0.38 10.3 12.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_C98 PF15499.6 KFP17133.1 - 0.46 9.9 4.6 0.27 10.7 2.6 1.6 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4735 PF15882.5 KFP17133.1 - 1.9 7.9 7.0 1.3 8.5 1.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) Calpain_III PF01067.22 KFP17134.1 - 3.5e-13 50.0 4.2 3.1e-07 30.7 1.9 3.4 2 2 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KFP17135.1 - 9.1e-29 100.4 0.2 3.9e-26 91.8 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.18 KFP17135.1 - 1.1e-15 57.5 8.2 5.1e-13 48.9 4.1 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KFP17135.1 - 0.072 13.3 0.1 0.47 10.8 0.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat T2SSF PF00482.23 KFP17135.1 - 0.076 13.0 1.1 0.14 12.1 0.2 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TPR_12 PF13424.6 KFP17135.1 - 0.099 12.9 1.7 0.21 11.9 1.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP17135.1 - 0.12 12.0 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KFP17135.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Use1 PF09753.9 KFP17135.1 - 1.2 8.8 8.4 8.2 6.1 8.4 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 VWA PF00092.28 KFP17136.1 - 7.7e-45 153.3 7.3 1.6e-18 67.6 0.1 4.1 4 0 0 4 4 4 4 von Willebrand factor type A domain Collagen PF01391.18 KFP17136.1 - 1e-44 150.1 177.7 9.9e-09 34.8 22.0 6.8 2 1 4 6 6 6 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFP17136.1 - 1.6e-12 48.0 5.9 2.4e-07 31.4 0.0 4.4 4 1 0 4 4 4 2 von Willebrand factor type A domain VWA_3 PF13768.6 KFP17136.1 - 0.00051 20.0 1.8 1.3 8.9 0.1 4.0 4 0 0 4 4 4 2 von Willebrand factor type A domain Regulator_TrmB PF11495.8 KFP17136.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB VWA PF00092.28 KFP17137.1 - 8.1e-08 32.7 0.0 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3926 PF13080.6 KFP17137.1 - 0.21 11.5 1.6 0.43 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) RVT_1 PF00078.27 KFP17139.1 - 0.005 16.4 0.0 0.0094 15.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gag_p30 PF02093.16 KFP17140.1 - 2.9e-27 95.6 0.1 3.6e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.20 KFP17140.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Pkinase PF00069.25 KFP17141.1 - 3.9e-19 69.0 0.0 2.8e-12 46.6 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 KFP17141.1 - 7.2e-13 48.8 19.2 4.5e-05 24.1 0.3 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.22 KFP17141.1 - 3.9e-09 36.0 0.4 0.71 10.3 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.17 KFP17141.1 - 9e-07 28.4 0.0 1e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KFP17141.1 - 0.00032 20.9 0.2 2.4 8.5 0.0 4.5 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KFP17141.1 - 0.068 13.6 0.1 2.8 8.4 0.0 3.2 2 2 0 2 2 2 0 HEAT repeats Nucleoporin_N PF08801.11 KFP17141.1 - 0.083 11.6 0.1 14 4.3 0.0 3.1 3 0 0 3 3 3 0 Nup133 N terminal like E1-E2_ATPase PF00122.20 KFP17143.1 - 1.1e-49 168.5 0.1 1.1e-49 168.5 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP17143.1 - 4.1e-46 157.0 3.9 4.1e-46 157.0 3.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFP17143.1 - 1.9e-21 77.3 2.5 8.1e-21 75.3 2.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP17143.1 - 2e-16 59.8 0.0 2.9e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP17143.1 - 0.0004 20.2 2.7 0.00082 19.2 2.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KFP17144.1 - 6.7e-63 212.5 0.3 1.2e-62 211.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17144.1 - 1.1e-45 156.0 0.0 2.1e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP17144.1 - 0.0015 17.4 1.8 0.0047 15.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP17144.1 - 0.011 15.6 0.2 0.039 13.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP17144.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSP_NTD PF17804.1 KFP17144.1 - 0.21 11.8 9.2 0.045 14.0 3.8 2.3 2 1 0 2 2 2 0 Tail specific protease N-terminal domain DHR10 PF18595.1 KFP17144.1 - 7.9 6.6 15.9 1.3 9.1 9.2 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Ribosomal_L3 PF00297.22 KFP17145.1 - 9.2e-55 186.1 0.2 8.2e-52 176.4 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Copine PF07002.16 KFP17146.1 - 1.9e-95 318.4 0.0 2.7e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP17146.1 - 1.9e-27 95.6 0.1 1.2e-13 51.2 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP17146.1 - 3.3e-05 24.1 0.0 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KFP17146.1 - 0.00061 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain His_Phos_2 PF00328.22 KFP17148.1 - 3.3e-35 122.2 3.6 1.1e-33 117.2 3.6 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Toxin_TOLIP PF00087.21 KFP17148.1 - 0.12 12.6 1.1 0.37 11.1 0.2 2.1 2 0 0 2 2 2 0 Snake toxin and toxin-like protein GYF_2 PF14237.6 KFP17149.1 - 1.8e-18 66.1 1.0 4.5e-18 64.8 1.0 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 KFP17149.1 - 2.3e-15 56.5 2.9 4.5e-15 55.5 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain Adaptin_N PF01602.20 KFP17149.1 - 0.0047 15.6 2.8 3.1 6.3 0.1 3.9 3 0 0 3 3 3 2 Adaptin N terminal region TetR_C_15 PF17918.1 KFP17149.1 - 0.034 14.9 0.0 11 6.9 0.0 3.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GYF PF02213.16 KFP17149.1 - 0.11 12.2 4.1 0.068 12.8 1.8 2.0 2 0 0 2 2 2 0 GYF domain DUF3361 PF11841.8 KFP17149.1 - 5.5 6.9 6.0 4.1 7.3 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) 7tm_1 PF00001.21 KFP17150.1 - 1e-48 165.9 17.8 1.4e-48 165.6 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17150.1 - 1.2e-05 24.8 16.9 1.6e-05 24.4 16.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF621 PF04789.15 KFP17150.1 - 0.0094 15.1 7.5 0.0094 15.1 7.5 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF621) SirB PF04247.12 KFP17150.1 - 0.014 15.4 1.5 0.014 15.4 1.5 2.2 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB ThiF PF00899.21 KFP17151.1 - 2e-49 168.2 0.1 2.7e-49 167.7 0.1 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KFP17151.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFP17151.1 - 0.028 14.7 2.2 0.41 10.9 0.6 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KFP17151.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFP17151.1 - 0.053 12.9 0.3 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFP17151.1 - 0.12 12.1 0.1 0.55 9.9 0.1 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KFP17151.1 - 0.14 11.4 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KFP17151.1 - 0.16 12.2 0.4 1.8 8.9 0.0 2.8 4 0 0 4 4 4 0 TrkA-N domain TPR_12 PF13424.6 KFP17152.1 - 3e-75 248.5 22.9 9.1e-19 67.5 0.0 7.3 3 2 3 7 7 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFP17152.1 - 7.6e-67 219.6 22.0 6.8e-12 44.9 0.5 9.6 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 KFP17152.1 - 2.8e-31 106.0 34.8 6.4e-06 25.8 2.7 9.1 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFP17152.1 - 4.4e-31 104.6 19.2 0.00029 20.6 0.1 10.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFP17152.1 - 1.8e-23 80.8 32.8 8.9e-05 22.4 1.6 9.6 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP17152.1 - 4.6e-20 70.0 33.7 0.0028 17.6 0.2 9.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP17152.1 - 2.1e-17 63.5 9.2 0.00012 21.6 2.2 4.6 1 1 3 4 4 4 4 MalT-like TPR region TPR_16 PF13432.6 KFP17152.1 - 1.7e-12 47.7 15.4 0.00032 21.3 0.3 7.3 3 2 5 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP17152.1 - 1.9e-10 41.1 18.7 0.0096 16.4 0.5 5.7 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP17152.1 - 2.5e-10 40.0 14.3 0.056 13.8 0.1 8.6 8 2 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP17152.1 - 3.7e-07 30.4 16.9 3.8 8.6 0.2 8.6 4 2 4 8 8 8 1 Tetratricopeptide repeat NACHT PF05729.12 KFP17152.1 - 6.3e-07 29.5 0.5 1.7e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 NACHT domain TPR_11 PF13414.6 KFP17152.1 - 3.9e-06 26.4 24.0 0.26 11.0 0.2 8.1 8 0 0 8 8 8 2 TPR repeat TPR_6 PF13174.6 KFP17152.1 - 9.4e-05 22.8 18.0 1.6 9.5 0.1 7.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFP17152.1 - 0.00059 19.8 21.4 1.7 8.7 0.4 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF2225 PF09986.9 KFP17152.1 - 0.0011 18.7 0.1 0.0011 18.7 0.1 4.7 2 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) AAA_16 PF13191.6 KFP17152.1 - 0.0015 18.9 4.0 0.0018 18.7 0.1 3.1 3 1 0 3 3 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KFP17152.1 - 0.002 17.4 1.3 0.15 11.3 0.0 3.1 3 1 1 4 4 4 1 KAP family P-loop domain AAA_22 PF13401.6 KFP17152.1 - 0.0024 18.2 0.4 0.018 15.3 0.0 2.8 3 0 0 3 3 1 1 AAA domain AAA_19 PF13245.6 KFP17152.1 - 0.0027 18.0 0.0 0.018 15.4 0.0 2.5 1 0 0 1 1 1 1 AAA domain MIT PF04212.18 KFP17152.1 - 0.0092 16.0 22.0 2.8 8.1 2.4 6.3 4 1 1 5 5 5 1 MIT (microtubule interacting and transport) domain 14-3-3 PF00244.20 KFP17152.1 - 0.065 12.7 21.6 1.4 8.4 0.0 5.5 3 1 2 5 5 4 0 14-3-3 protein AAA_33 PF13671.6 KFP17152.1 - 0.09 12.9 3.3 4.3 7.5 2.3 2.5 2 0 0 2 2 2 0 AAA domain DUF4404 PF14357.6 KFP17152.1 - 0.12 13.1 14.4 12 6.6 0.0 6.7 4 4 3 7 7 7 0 Domain of unknown function (DUF4404) AAA PF00004.29 KFP17152.1 - 0.13 12.7 0.0 0.46 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ANAPC5 PF12862.7 KFP17152.1 - 0.18 11.9 2.1 14 5.8 0.5 3.8 3 2 0 3 3 2 0 Anaphase-promoting complex subunit 5 GIT_CC PF16559.5 KFP17152.1 - 0.2 11.6 6.7 2.6 8.0 0.3 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2075 PF09848.9 KFP17152.1 - 0.4 9.9 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Tcf25 PF04910.14 KFP17152.1 - 0.64 9.0 4.8 11 5.0 0.1 4.5 4 2 2 6 6 6 0 Transcriptional repressor TCF25 SHNi-TPR PF10516.9 KFP17152.1 - 1 8.8 9.5 2.4 7.7 0.1 5.5 7 0 0 7 7 6 0 SHNi-TPR FliD_C PF07195.12 KFP17152.1 - 2.1 7.7 10.8 8.3 5.8 0.3 3.2 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Uso1_p115_C PF04871.13 KFP17152.1 - 2.4 8.5 27.1 0.019 15.3 13.8 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region OmpH PF03938.14 KFP17152.1 - 4.5 7.6 31.1 0.092 13.1 15.6 3.4 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) TMEM108 PF15759.5 KFP17154.1 - 8.5e-134 447.4 9.5 9.6e-134 447.2 9.5 1.0 1 0 0 1 1 1 1 TMEM108 family Filament PF00038.21 KFP17155.1 - 7.4e-58 196.6 25.4 8.9e-58 196.3 25.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Lectin_N PF03954.14 KFP17155.1 - 0.06 13.1 6.1 0.22 11.3 1.6 2.5 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain FTA4 PF13093.6 KFP17155.1 - 0.17 11.8 11.7 1.1 9.1 11.7 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Baculo_PEP_C PF04513.12 KFP17155.1 - 0.44 10.6 5.4 0.96 9.5 0.2 2.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 KFP17155.1 - 2.8 6.7 21.6 0.11 11.4 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF812) DUF1759 PF03564.15 KFP17155.1 - 5 7.0 8.5 1.8 8.5 0.9 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) CDV3 PF15359.6 KFP17158.1 - 4e-43 147.0 8.2 5.7e-43 146.5 8.2 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 MecA_N PF05223.11 KFP17158.1 - 0.21 11.8 2.2 4 7.7 0.6 2.1 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain BRCT PF00533.26 KFP17159.1 - 6e-42 141.9 0.7 2.5e-18 66.2 0.1 3.2 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFP17159.1 - 1.1e-41 140.6 4.1 9.2e-25 86.4 1.0 3.3 3 0 0 3 3 3 3 twin BRCT domain BRCT_2 PF16589.5 KFP17159.1 - 1.5e-17 63.8 0.5 1.4e-08 35.1 0.0 3.3 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFP17159.1 - 1.5e-14 54.0 0.0 1.9e-07 31.2 0.0 3.2 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KFP17159.1 - 1.5e-06 28.0 0.0 0.26 11.2 0.0 3.4 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain 7tm_1 PF00001.21 KFP17160.1 - 2.9e-53 180.9 18.5 3.6e-53 180.6 18.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17160.1 - 7.9e-09 35.3 20.0 1.1e-08 34.8 20.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 KFP17161.1 - 2.1e-54 184.6 20.2 2.6e-54 184.3 20.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17161.1 - 4e-10 39.5 22.1 5.1e-10 39.2 22.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PspC PF04024.12 KFP17161.1 - 0.26 11.1 0.2 0.26 11.1 0.2 2.3 2 0 0 2 2 2 0 PspC domain Sprouty PF05210.13 KFP17161.1 - 0.89 10.0 3.6 17 5.8 0.1 2.8 2 1 0 2 2 2 0 Sprouty protein (Spry) COX7C PF02935.16 KFP17161.1 - 1.6 9.1 5.4 7 7.0 1.2 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc 7tm_1 PF00001.21 KFP17162.1 - 2.5e-46 158.1 20.3 3.5e-46 157.7 20.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FYVE PF01363.21 KFP17163.1 - 3.6e-16 59.1 18.9 1.4e-15 57.1 18.9 2.1 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 KFP17163.1 - 2.9e-08 33.8 0.0 2.9e-08 33.8 0.0 5.7 4 2 0 4 4 4 1 RUN domain GOLD_2 PF13897.6 KFP17163.1 - 4.9e-05 23.8 0.0 4.9e-05 23.8 0.0 6.4 6 3 2 8 8 8 1 Golgi-dynamics membrane-trafficking CBM_48 PF02922.18 KFP17168.1 - 5.1e-17 62.0 0.1 1.1e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 KFP17168.1 - 1e-15 57.9 0.1 2.9e-15 56.5 0.1 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFP17168.1 - 1.9e-14 54.0 2.8 3.7e-12 46.4 0.2 2.6 2 1 1 3 3 3 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFP17168.1 - 0.022 13.8 0.4 0.047 12.8 0.1 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain ATP-synt_Eps PF04627.13 KFP17170.1 - 1.2e-16 60.4 3.0 1.3e-16 60.3 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Pep3_Vps18 PF05131.14 KFP17172.1 - 1.6e-41 141.6 0.2 2.5e-40 137.7 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFP17172.1 - 1.8e-11 44.1 19.9 2.3e-09 37.3 3.8 3.0 3 1 0 3 3 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KFP17172.1 - 0.0014 18.4 1.3 0.0014 18.4 1.3 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFP17172.1 - 0.0018 17.9 0.1 0.0018 17.9 0.1 2.4 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 KFP17172.1 - 0.0027 18.1 1.9 0.0045 17.4 0.4 2.3 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KFP17172.1 - 0.006 16.5 0.3 0.027 14.4 0.3 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP17172.1 - 0.015 15.3 0.5 0.054 13.5 0.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFP17172.1 - 0.02 15.2 0.5 0.02 15.2 0.5 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KFP17172.1 - 0.024 14.4 0.9 0.024 14.4 0.9 2.7 2 0 0 2 2 2 0 RING-like zinc finger Nup54_57_C PF18570.1 KFP17172.1 - 0.031 13.8 1.6 0.099 12.3 0.6 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain zf-ANAPC11 PF12861.7 KFP17172.1 - 0.034 14.2 0.2 0.12 12.4 0.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF5600 PF18150.1 KFP17172.1 - 0.035 14.7 0.1 0.26 11.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) DUF2229 PF09989.9 KFP17172.1 - 0.059 13.0 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-rbx1 PF12678.7 KFP17172.1 - 0.059 13.7 0.2 0.059 13.7 0.2 2.4 2 0 0 2 2 1 0 RING-H2 zinc finger domain Taxilin PF09728.9 KFP17172.1 - 0.071 12.3 4.2 0.047 12.9 0.4 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF1664 PF07889.12 KFP17172.1 - 0.091 12.8 1.4 0.22 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KNOX2 PF03791.13 KFP17172.1 - 0.15 11.6 1.9 0.29 10.7 0.3 2.4 2 0 0 2 2 2 0 KNOX2 domain Fib_alpha PF08702.10 KFP17172.1 - 0.35 11.1 2.9 0.98 9.6 0.2 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_S PF02609.16 KFP17172.1 - 2.9 8.0 6.7 22 5.2 1.5 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit XhlA PF10779.9 KFP17172.1 - 5.3 7.3 6.9 0.82 9.9 2.3 2.1 2 0 0 2 2 1 0 Haemolysin XhlA EF-hand_7 PF13499.6 KFP17173.1 - 8.7e-18 64.5 3.1 3.7e-13 49.7 0.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP17173.1 - 1.7e-16 58.6 1.3 5.9e-07 28.9 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KFP17173.1 - 1.7e-16 58.4 2.7 1.9e-06 27.0 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFP17173.1 - 1.1e-07 31.6 1.6 3.2e-05 23.7 0.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP17173.1 - 2.1e-07 30.1 3.7 0.014 14.9 0.2 3.4 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KFP17173.1 - 3.2e-05 24.2 0.0 0.0014 18.9 0.1 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 KFP17173.1 - 0.00084 19.2 0.3 0.0039 17.1 0.0 2.2 3 0 0 3 3 3 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 KFP17173.1 - 0.062 13.3 1.3 2.1 8.3 0.2 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand NUSAP PF16006.5 KFP17174.1 - 1.6e-117 392.5 23.4 1.6e-117 392.5 23.4 2.2 2 0 0 2 2 2 1 Nucleolar and spindle-associated protein TRAUB PF08164.12 KFP17174.1 - 0.019 15.4 0.1 0.019 15.4 0.1 3.8 3 2 1 4 4 4 0 Apoptosis-antagonizing transcription factor, C-terminal Plus-3 PF03126.18 KFP17175.1 - 1.4e-36 125.3 0.1 1.4e-36 125.3 0.1 2.8 2 0 0 2 2 2 1 Plus-3 domain Sulfotransfer_2 PF03567.14 KFP17176.1 - 1.2e-44 153.1 1.3 1.4e-44 152.9 1.3 1.0 1 0 0 1 1 1 1 Sulfotransferase family Complex1_LYR PF05347.15 KFP17176.1 - 0.045 13.8 1.8 0.081 13.0 0.2 2.3 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Pkip-1 PF06878.11 KFP17176.1 - 0.075 13.1 1.8 0.073 13.2 0.4 1.7 2 1 0 2 2 2 0 Pkip-1 protein IPK PF03770.16 KFP17177.1 - 2.4e-42 145.1 0.0 5.9e-42 143.8 0.0 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Pkinase_Tyr PF07714.17 KFP17178.1 - 5.9e-87 291.2 0.0 7.6e-87 290.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP17178.1 - 3.9e-31 108.4 0.0 5.5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.7 KFP17178.1 - 4.9e-21 75.8 25.4 7.9e-21 75.1 25.4 1.2 1 0 0 1 1 1 1 Glycine rich protein FXa_inhibition PF14670.6 KFP17178.1 - 0.2 12.0 7.5 0.68 10.3 7.5 2.0 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site RPAP1_C PF08620.10 KFP17179.1 - 9.2e-27 93.0 0.7 9.2e-27 93.0 0.7 2.1 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KFP17179.1 - 2.2e-16 59.4 3.3 2.2e-16 59.4 3.3 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal TMEM151 PF14857.6 KFP17180.1 - 3.2e-198 658.9 15.0 3.6e-198 658.8 15.0 1.0 1 0 0 1 1 1 1 TMEM151 family Pkinase_Tyr PF07714.17 KFP17181.1 - 6.8e-86 287.7 0.0 9.2e-86 287.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP17181.1 - 1.1e-35 123.3 0.0 1.6e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFP17181.1 - 1.4e-18 67.2 0.3 2.1e-10 41.0 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP17181.1 - 2.6e-17 62.7 1.1 4.3e-14 52.4 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain fn3 PF00041.21 KFP17181.1 - 1.4e-15 57.4 0.6 1.7e-09 37.9 0.3 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.6 KFP17181.1 - 3.6e-14 52.9 0.0 6.1e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP17181.1 - 3.3e-12 46.4 0.2 8e-09 35.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP17181.1 - 9.6e-06 25.7 0.0 0.0021 18.2 0.0 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kinase-like PF14531.6 KFP17181.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4381 PF14316.6 KFP17181.1 - 1.6 9.0 3.9 0.61 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) WD40 PF00400.32 KFP17183.1 - 7.2e-34 115.3 21.0 0.0014 19.5 0.3 11.9 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17183.1 - 4.6e-11 42.9 1.9 0.0025 18.1 0.0 6.4 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP17183.1 - 0.018 14.4 1.9 2.2 7.5 0.1 3.8 4 0 0 4 4 4 0 WD40-like domain DUF5600 PF18150.1 KFP17185.1 - 2.5e-46 156.7 1.8 4.8e-46 155.7 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KFP17185.1 - 6.5e-16 58.2 0.0 2.8e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 KFP17185.1 - 3.6e-06 27.1 0.0 2e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 Dynamin family EF-hand_1 PF00036.32 KFP17185.1 - 0.0004 19.7 0.6 0.0017 17.8 0.1 2.4 2 0 0 2 2 2 1 EF hand MMR_HSR1 PF01926.23 KFP17185.1 - 0.0023 18.0 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 KFP17185.1 - 0.0087 16.5 0.0 0.065 13.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP17185.1 - 0.073 12.9 0.7 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair PLA2_B PF01735.18 KFP17186.1 - 1.2e-27 96.5 0.0 1.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP17186.1 - 1.2e-16 60.7 0.0 2.9e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain PLA2_B PF01735.18 KFP17187.1 - 2.7e-37 128.4 0.1 1.2e-33 116.3 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP17187.1 - 6.2e-23 80.9 1.2 6.2e-23 80.9 1.2 2.7 3 0 0 3 3 3 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP17187.1 - 5.2e-18 65.2 0.2 5.2e-18 65.2 0.2 1.9 2 0 0 2 2 2 1 C2 domain PLA2_B PF01735.18 KFP17188.1 - 1.4e-34 119.4 0.1 6.4e-32 110.6 0.0 2.9 2 1 1 3 3 3 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP17188.1 - 3e-22 78.7 0.0 8.6e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP17188.1 - 2.2e-13 50.4 0.1 6.3e-13 48.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain PLA2_B PF01735.18 KFP17189.1 - 3.2e-29 101.7 0.0 3.4e-27 95.0 0.0 2.5 2 1 1 3 3 3 2 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP17189.1 - 2.7e-19 69.2 1.9 9.6e-19 67.4 0.3 2.4 2 0 0 2 2 2 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP17189.1 - 9.3e-14 51.6 0.2 2e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 KFP17190.1 - 9.5e-16 58.0 1.2 1.5e-15 57.3 0.4 1.6 1 1 1 2 2 2 1 C2 domain PLA2_B PF01735.18 KFP17191.1 - 7.5e-29 100.5 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP17191.1 - 1.7e-19 69.9 0.0 3.3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain PLA2_B PF01735.18 KFP17192.1 - 1.3e-39 136.0 0.2 6.1e-33 114.0 0.0 3.0 2 1 1 3 3 3 3 Lysophospholipase catalytic domain cPLA2_C2 PF18695.1 KFP17192.1 - 6e-26 90.6 0.5 1.1e-25 89.7 0.5 1.5 1 0 0 1 1 1 1 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP17192.1 - 8.5e-17 61.3 0.1 7.1e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 C2 domain Vps39_1 PF10366.9 KFP17193.1 - 3e-32 111.1 2.7 3e-32 111.1 2.7 3.3 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFP17193.1 - 2.1e-31 108.6 4.8 2.1e-31 108.6 4.8 2.8 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KFP17193.1 - 6.3e-30 104.7 0.1 1.4e-29 103.6 0.1 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 KFP17193.1 - 1.2e-11 44.6 12.4 1.4e-06 28.2 1.3 4.2 3 1 0 3 3 3 2 Region in Clathrin and VPS Lung_7-TM_R PF06814.13 KFP17194.1 - 2.3e-78 263.4 25.7 9.9e-77 258.1 25.7 2.2 1 1 0 1 1 1 1 Lung seven transmembrane receptor SNAD4 PF18750.1 KFP17194.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 SPT6_acidic PF14632.6 KFP17194.1 - 0.047 14.3 1.1 0.11 13.1 1.1 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 APOBEC2 PF18772.1 KFP17194.1 - 0.095 12.7 0.2 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 APOBEC2 NAD1 PF18778.1 KFP17194.1 - 0.11 12.6 0.5 0.25 11.4 0.1 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Glyco_hydro_31 PF01055.26 KFP17195.1 - 2.8e-144 481.6 1.4 4.5e-144 480.9 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFP17195.1 - 3.2e-17 62.6 0.1 1.9e-16 60.1 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP17195.1 - 9.2e-05 22.6 0.0 0.00026 21.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NtCtMGAM_N PF16863.5 KFP17195.1 - 0.00015 21.9 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Peptidase_C2 PF00648.21 KFP17196.1 - 1.8e-139 463.8 0.4 2.7e-139 463.3 0.4 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP17196.1 - 1.1e-52 178.0 0.0 2.7e-52 176.8 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III Calpain_u2 PF16648.5 KFP17196.1 - 4.2e-19 68.8 8.6 8.5e-18 64.6 2.5 2.5 2 0 0 2 2 2 2 Unstructured region on Calpain-3 EF-hand_1 PF00036.32 KFP17196.1 - 1.4e-17 61.8 11.8 2.9e-07 29.6 0.1 5.9 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFP17196.1 - 3.3e-15 54.6 9.1 0.00025 20.7 0.0 5.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 KFP17196.1 - 2.5e-12 46.4 11.0 7e-10 38.6 0.6 4.7 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP17196.1 - 4.9e-11 41.6 5.4 0.0014 18.0 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFP17196.1 - 1.7e-10 41.2 8.8 0.00017 22.0 0.4 4.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KFP17196.1 - 0.014 15.4 4.1 0.26 11.3 0.5 2.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ndufs5 PF10200.9 KFP17196.1 - 0.34 11.2 2.1 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa K_channel_TID PF07941.11 KFP17196.1 - 1.1 9.8 2.8 2.3 8.7 2.8 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.32 KFP17197.1 - 3.9e-18 65.5 4.9 0.016 16.0 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17197.1 - 1.1e-06 28.8 2.7 1.3 9.3 0.0 5.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFP17197.1 - 0.0017 18.8 2.0 61 4.3 0.0 5.4 6 0 0 6 6 6 0 PQQ-like domain zf-C2H2_aberr PF17017.5 KFP17197.1 - 0.0043 17.2 0.3 0.0097 16.1 0.3 1.6 1 0 0 1 1 1 1 Aberrant zinc-finger WD40_like PF17005.5 KFP17197.1 - 0.024 14.0 3.1 0.18 11.1 0.2 2.1 2 0 0 2 2 2 0 WD40-like domain FOXP-CC PF16159.5 KFP17197.1 - 0.064 13.9 5.6 0.74 10.5 3.9 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain SNAP-25 PF00835.19 KFP17198.1 - 6.6e-22 77.6 0.5 1.2e-21 76.7 0.5 1.5 1 0 0 1 1 1 1 SNAP-25 family DUF5089 PF17002.5 KFP17198.1 - 2.5e-06 27.5 1.8 5.6e-06 26.4 1.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KFP17198.1 - 0.00031 21.0 5.1 0.014 15.6 1.2 2.5 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFP17198.1 - 0.048 13.6 0.7 0.11 12.4 0.7 1.6 1 0 0 1 1 1 0 Sec20 DUF16 PF01519.16 KFP17198.1 - 0.048 14.1 3.0 6.4 7.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 SOAR PF16533.5 KFP17198.1 - 0.049 13.6 0.5 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF1664 PF07889.12 KFP17198.1 - 0.12 12.4 5.0 0.35 10.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KFP17198.1 - 0.74 10.1 2.4 7.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LRR_8 PF13855.6 KFP17199.1 - 5.9e-32 109.2 52.6 2.1e-11 43.4 8.1 4.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP17199.1 - 1.5e-20 72.9 28.8 1.8e-06 28.1 3.8 4.7 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP17199.1 - 5.5e-09 35.8 8.9 7.5e-06 25.5 1.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP17199.1 - 4.3e-08 32.6 24.5 0.33 11.7 0.3 7.6 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP17199.1 - 2.9e-05 23.8 24.7 2.9 8.2 0.1 7.5 7 0 0 7 7 7 4 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KFP17199.1 - 0.0012 18.9 0.3 1.2 9.2 0.1 4.1 2 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain HAUS2 PF15003.6 KFP17200.1 - 6.8e-40 136.8 3.7 9e-40 136.4 3.7 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 T2SSF PF00482.23 KFP17200.1 - 0.014 15.3 1.3 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Kinesin PF00225.23 KFP17201.1 - 4.1e-100 334.9 0.0 4.1e-100 334.9 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP17201.1 - 1.8e-24 86.4 0.0 3e-23 82.4 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 KFP17201.1 - 5e-06 26.8 1.7 1.3e-05 25.5 0.2 2.5 2 0 0 2 2 2 1 FHA domain Kinesin_assoc PF16183.5 KFP17201.1 - 1.4e-05 25.3 13.3 3.5e-05 24.0 0.5 4.0 3 2 1 4 4 4 2 Kinesin-associated Yop-YscD_cpl PF16697.5 KFP17201.1 - 0.00023 21.4 0.0 0.0011 19.3 0.0 2.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain START PF01852.19 KFP17202.1 - 9.8e-11 41.4 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 START domain Acyl-CoA_dh_2 PF08028.11 KFP17202.1 - 0.13 12.6 1.6 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1168 PF06658.12 KFP17202.1 - 2.5 7.9 12.3 2.1 8.1 7.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Codanin-1_C PF15296.6 KFP17203.1 - 1.8e-40 137.8 0.1 4.2e-40 136.6 0.1 1.7 1 0 0 1 1 1 1 Codanin-1 C-terminus PET PF06297.14 KFP17204.1 - 5.5e-39 132.4 1.1 1.6e-38 130.9 1.1 1.8 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFP17204.1 - 3.6e-25 88.0 40.3 2e-09 37.5 3.3 3.7 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.6 KFP17204.1 - 0.0027 18.5 0.6 0.015 16.2 0.0 2.4 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 RRM_1 PF00076.22 KFP17205.1 - 3.1e-22 78.2 0.2 5e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP17205.1 - 7.4e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KFP17205.1 - 3.2e-05 23.8 2.0 5.6e-05 23.0 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle SET_assoc PF11767.8 KFP17205.1 - 0.0098 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-CCHC_3 PF13917.6 KFP17205.1 - 0.011 15.7 0.9 0.021 14.8 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle BRAP2 PF07576.12 KFP17205.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_7 PF16367.5 KFP17205.1 - 0.018 15.1 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 KFP17205.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFP17205.1 - 0.037 14.1 0.3 0.16 12.0 0.3 2.0 1 1 0 1 1 1 0 Limkain b1 YAF2_RYBP PF17219.3 KFP17206.1 - 1.1e-19 69.7 0.2 1.8e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif U3_snoRNA_assoc PF08297.11 KFP17206.1 - 0.63 10.8 12.2 1.3 9.7 12.2 1.6 1 1 0 1 1 1 0 U3 snoRNA associated CPSF100_C PF13299.6 KFP17206.1 - 4.3 7.5 9.6 1 9.5 5.9 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RAP1 PF07218.11 KFP17206.1 - 5.6 5.1 11.6 6.3 4.9 11.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_transf_8 PF01501.20 KFP17208.1 - 1e-07 31.8 0.7 2e-07 30.8 0.7 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP17208.1 - 0.017 14.6 0.1 0.023 14.1 0.1 1.4 1 1 0 1 1 1 0 Glucosyltransferase 24 PDZ PF00595.24 KFP17210.1 - 2e-20 72.9 0.2 2.2e-15 56.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP17210.1 - 1.2e-15 57.1 1.5 3.4e-13 49.2 0.3 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP17210.1 - 3e-07 30.6 0.1 1.1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFP17210.1 - 0.019 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ig_3 PF13927.6 KFP17216.1 - 7.7e-76 250.7 0.4 1.2e-12 48.2 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP17216.1 - 1e-68 227.4 0.0 5.2e-12 45.7 0.0 7.0 7 0 0 7 7 6 6 Immunoglobulin I-set domain fn3 PF00041.21 KFP17216.1 - 3e-63 210.1 15.2 2.7e-14 53.3 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFP17216.1 - 2.2e-47 159.3 0.1 4.1e-08 33.4 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFP17216.1 - 2.2e-43 146.3 0.0 1.2e-07 31.7 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFP17216.1 - 6.9e-27 94.6 6.8 1.5e-26 93.6 6.8 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFP17216.1 - 6.7e-14 52.0 2.6 0.066 13.4 0.0 8.8 8 3 0 8 8 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP17216.1 - 2.2e-12 46.8 0.1 0.16 12.1 0.0 6.5 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP17216.1 - 1.7e-10 40.3 1.8 0.4 10.3 0.0 6.0 7 0 0 7 7 7 3 Immunoglobulin domain Ig_5 PF16681.5 KFP17216.1 - 4.2e-07 30.3 0.0 0.24 11.8 0.0 5.4 6 1 0 6 6 5 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP17216.1 - 3.5e-06 27.2 0.1 4.3 7.7 0.0 5.4 6 0 0 6 6 5 1 T-cell surface glycoprotein CD3 delta chain Pur_ac_phosph_N PF16656.5 KFP17216.1 - 4.3e-06 27.2 3.9 0.031 14.8 0.1 5.4 5 0 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFP17216.1 - 0.0032 17.5 0.0 37 4.4 0.0 5.3 6 0 0 6 6 5 0 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP17216.1 - 0.0048 16.9 0.1 4.3 7.5 0.0 3.7 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain SIT PF15330.6 KFP17216.1 - 0.0053 17.2 0.0 0.34 11.4 0.0 2.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT V-set_CD47 PF08204.11 KFP17216.1 - 0.0053 16.7 3.6 3 7.8 0.0 3.8 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFP17216.1 - 0.016 14.9 3.6 0.22 11.3 0.0 4.0 5 0 0 5 5 4 0 Adenovirus E3 region protein CR1 INCA1 PF15142.6 KFP17216.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 INCA1 Patatin PF01734.22 KFP17217.1 - 2.1e-23 83.6 0.0 1.7e-22 80.6 0.0 2.4 3 0 0 3 3 3 1 Patatin-like phospholipase 7tm_1 PF00001.21 KFP17218.1 - 6.3e-41 140.4 22.7 7.8e-41 140.1 22.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17218.1 - 0.00093 18.7 23.6 0.0022 17.4 23.6 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP17218.1 - 0.0035 17.1 5.4 0.0035 17.1 5.4 1.9 2 0 0 2 2 2 1 Olfactory receptor THAP PF05485.12 KFP17219.1 - 7.1e-10 39.7 0.2 2.1e-09 38.2 0.2 1.9 1 0 0 1 1 1 1 THAP domain CENP-R PF06729.12 KFP17219.1 - 1.3 9.0 8.9 0.69 9.8 1.3 2.6 3 0 0 3 3 3 0 Kinetochore component, CENP-R DnaJ PF00226.31 KFP17220.1 - 2.6e-28 98.0 2.2 4.6e-28 97.1 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain Nramp PF01566.18 KFP17223.1 - 1.8e-106 356.2 10.3 3.2e-106 355.3 10.3 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Lactamase_B PF00753.27 KFP17225.1 - 0.053 13.5 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily WD40 PF00400.32 KFP17226.1 - 3.6e-29 100.4 16.8 1.3e-05 25.8 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17226.1 - 2.4e-20 72.6 1.8 2e-06 28.0 0.0 5.5 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP17226.1 - 4e-08 33.4 0.2 0.011 15.7 0.1 3.6 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFP17226.1 - 2.4e-05 23.8 0.0 0.31 10.3 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain PQQ PF01011.21 KFP17226.1 - 0.01 15.7 3.6 1.5 8.9 0.0 4.3 4 0 0 4 4 4 0 PQQ enzyme repeat Nup160 PF11715.8 KFP17226.1 - 0.018 13.7 0.4 0.64 8.6 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP17226.1 - 0.1 11.6 0.3 1.1 8.1 0.0 2.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein P34-Arc PF04045.14 KFP17227.1 - 1.4e-101 339.2 1.9 1.7e-101 339.0 1.9 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KFP17227.1 - 0.026 14.1 0.1 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Calici_coat PF00915.20 KFP17227.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein RUN PF02759.19 KFP17228.1 - 2.5e-08 34.0 0.0 2.9e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 RUN domain PTB PF08416.13 KFP17229.1 - 3.2e-38 130.8 0.0 6.4e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.9 KFP17229.1 - 1.8e-32 111.9 0.0 2.7e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.24 KFP17229.1 - 8.7e-09 35.4 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Peptidase_C12 PF01088.21 KFP17235.1 - 1e-60 205.1 0.0 1.9e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFP17235.1 - 2e-20 72.4 4.8 4.1e-20 71.4 4.8 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases RcsD_ABL PF16359.5 KFP17235.1 - 0.011 15.9 0.5 0.021 14.9 0.5 1.4 1 0 0 1 1 1 0 RcsD-ABL domain TROVE PF05731.11 KFP17236.1 - 1.6e-51 175.7 0.8 9e-48 163.4 1.2 2.3 1 1 1 2 2 2 2 TROVE domain DUF2201 PF09967.9 KFP17236.1 - 0.0029 17.8 0.4 0.012 15.8 0.1 2.0 2 0 0 2 2 2 1 VWA-like domain (DUF2201) Galactosyl_T PF01762.21 KFP17237.1 - 7.4e-66 221.7 0.0 1.1e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase RVT_1 PF00078.27 KFP17239.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP17239.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase BK_channel_a PF03493.18 KFP17242.1 - 2.3e-31 107.9 1.6 5.1e-31 106.7 0.2 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KFP17242.1 - 1.5e-12 47.3 4.2 7.8e-12 45.0 4.1 2.2 2 0 0 2 2 2 1 Ion channel Castor_Poll_mid PF06241.12 KFP17242.1 - 0.039 13.9 0.0 2.1 8.3 0.0 2.8 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel DSPc PF00782.20 KFP17243.1 - 1e-31 109.5 0.0 1.5e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP17243.1 - 1.2e-06 28.8 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP17243.1 - 2.8e-06 27.1 0.1 3.5e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Prefoldin_2 PF01920.20 KFP17244.1 - 1.2e-05 25.2 0.7 1.6e-05 24.8 0.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit MICSWaP PF17018.5 KFP17244.1 - 0.13 11.8 0.4 0.14 11.7 0.4 1.1 1 0 0 1 1 1 0 Spore wall protein Pkinase_Tyr PF07714.17 KFP17245.1 - 2.8e-95 318.5 0.0 3.6e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP17245.1 - 5.7e-48 163.6 0.0 7.2e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 KFP17245.1 - 3.2e-15 55.5 0.0 6.6e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP17245.1 - 4.5e-12 45.6 0.0 9.6e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH2 PF00017.24 KFP17245.1 - 2.1e-11 43.8 0.0 6.1e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 SH2 domain SH3_2 PF07653.17 KFP17245.1 - 1.4e-08 34.3 0.0 2.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP17245.1 - 0.0026 16.8 0.1 0.0074 15.3 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain SH3_3 PF08239.11 KFP17245.1 - 0.004 17.4 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain EMP70 PF02990.16 KFP17246.1 - 1.6e-195 650.7 16.8 3.4e-195 649.6 16.8 1.5 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3817 PF12823.7 KFP17246.1 - 0.16 12.8 0.1 0.16 12.8 0.1 4.5 2 2 0 3 3 3 0 Domain of unknown function (DUF3817) zf-H2C2_2 PF13465.6 KFP17247.1 - 2.4e-21 75.1 47.1 5.9e-05 23.3 4.7 7.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP17247.1 - 2.7e-21 74.4 56.0 0.00064 20.3 1.4 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP17247.1 - 1.7e-17 62.8 61.5 7.4e-05 23.0 1.8 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP17247.1 - 5.9e-06 26.2 44.2 0.00046 20.1 0.8 6.9 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFP17247.1 - 0.00099 19.4 30.2 0.025 14.9 6.5 4.4 1 1 4 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFP17247.1 - 0.0063 16.2 2.0 0.13 12.0 0.3 5.8 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP17247.1 - 0.0071 16.6 29.4 0.42 11.0 2.9 6.3 5 1 1 6 6 6 2 Zinc-finger double-stranded RNA-binding Acyltransf_C PF16076.5 KFP17247.1 - 0.016 15.3 0.8 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Acyltransferase C-terminus zf-met2 PF12907.7 KFP17247.1 - 0.087 13.0 0.4 0.087 13.0 0.4 3.1 3 1 1 4 4 4 0 Zinc-binding Equine_IAV_S2 PF06502.11 KFP17247.1 - 0.16 12.0 0.3 0.47 10.6 0.3 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein HNH_5 PF14279.6 KFP17247.1 - 0.21 11.4 12.4 2.5 8.0 0.4 4.2 3 1 0 3 3 3 0 HNH endonuclease zf-met PF12874.7 KFP17247.1 - 0.26 11.7 21.9 1 9.9 0.2 5.1 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFP17247.1 - 0.52 10.7 38.5 1 9.7 1.2 6.2 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.12 KFP17247.1 - 1.3 8.6 4.9 3.9 7.1 0.4 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding FYDLN_acid PF09538.10 KFP17247.1 - 3.3 8.4 11.8 13 6.5 0.0 4.2 2 2 2 4 4 4 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_15 PF17032.5 KFP17247.1 - 8 7.3 17.7 1.5 9.6 2.2 3.7 2 1 1 4 4 4 0 zinc-ribbon family O-FucT PF10250.9 KFP17248.1 - 5.5e-43 148.0 0.0 6.6e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Kinesin PF00225.23 KFP17249.1 - 1.4e-122 408.8 1.0 1.4e-122 408.8 1.0 2.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP17249.1 - 9.9e-29 100.2 0.0 9.9e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KFP17249.1 - 0.098 13.0 0.0 0.098 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DUF948 PF06103.11 KFP17249.1 - 7.9 6.8 11.0 0.66 10.3 3.7 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ASXH PF13919.6 KFP17250.1 - 8.5e-37 126.3 0.1 2e-36 125.0 0.1 1.7 1 0 0 1 1 1 1 Asx homology domain HARE-HTH PF05066.13 KFP17250.1 - 7e-15 55.2 0.0 1.5e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain IMUP PF15761.5 KFP17250.1 - 0.049 14.3 0.4 0.049 14.3 0.4 4.4 4 1 0 4 4 4 0 Immortalisation up-regulated protein Integrase_H2C2 PF17921.1 KFP17251.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFP17251.1 - 0.11 12.8 0.3 0.25 11.6 0.3 1.7 1 1 0 1 1 1 0 H2C2 zinc finger COMM_domain PF07258.14 KFP17252.1 - 9.5e-18 64.1 0.1 2e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 COMM domain EB1 PF03271.17 KFP17253.1 - 3e-18 65.8 0.6 1.9e-17 63.2 0.7 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KFP17253.1 - 2e-12 47.3 0.7 3e-12 46.7 0.2 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain SUIM_assoc PF16619.5 KFP17253.1 - 0.099 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CAMSAP_CH PF11971.8 KFP17253.1 - 0.15 11.9 0.1 0.48 10.3 0.0 1.8 2 1 1 3 3 3 0 CAMSAP CH domain CCDC106 PF15794.5 KFP17253.1 - 0.21 11.3 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 LBP_BPI_CETP PF01273.25 KFP17254.1 - 4.2e-13 49.2 11.2 1.1e-11 44.7 7.8 2.8 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.17 KFP17254.1 - 5.2e-08 32.6 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain UPF0004 PF00919.20 KFP17255.1 - 1.7e-30 104.9 0.1 3.8e-30 103.8 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KFP17255.1 - 5.5e-30 104.9 0.0 1.1e-29 104.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 KFP17255.1 - 2.4e-11 43.4 0.0 4.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 TRAM domain LBP_BPI_CETP_C PF02886.17 KFP17256.1 - 4.8e-59 199.7 0.2 1.2e-58 198.4 0.2 1.7 1 1 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFP17256.1 - 5.4e-37 126.9 0.0 1.8e-36 125.2 0.0 1.9 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Ig_3 PF13927.6 KFP17257.1 - 3.4e-30 104.5 2.7 1.3e-09 38.5 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP17257.1 - 3.7e-23 81.4 0.5 4.9e-08 32.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP17257.1 - 2.8e-22 78.9 0.5 1.2e-06 28.8 0.1 3.2 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP17257.1 - 5.4e-21 74.6 3.7 2.2e-06 27.8 0.5 3.4 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 KFP17257.1 - 2.5e-17 62.7 1.3 2.1e-16 59.8 0.2 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP17257.1 - 3.2e-13 49.8 4.8 1.5e-07 31.6 0.0 3.9 3 2 1 4 4 4 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP17257.1 - 9.9e-07 29.1 3.1 0.034 14.6 0.0 4.1 4 1 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 KFP17257.1 - 1.4e-06 28.6 0.9 1e-05 25.8 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP17257.1 - 0.0036 17.3 0.0 5.1 7.2 0.0 2.7 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP17257.1 - 0.014 14.9 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain C2-set PF05790.15 KFP17257.1 - 0.045 13.9 6.0 5.3 7.3 1.7 3.7 4 1 0 4 4 4 0 Immunoglobulin C2-set domain DUF4307 PF14155.6 KFP17257.1 - 0.046 13.6 0.3 1 9.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Syndecan PF01034.20 KFP17257.1 - 0.15 12.0 0.0 2.1 8.3 0.0 2.7 3 0 0 3 3 2 0 Syndecan domain Pentaxin PF00354.17 KFP17258.1 - 2.5e-76 255.7 0.0 2.9e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP17258.1 - 5.7e-07 29.8 0.0 7.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4588 PF15251.6 KFP17261.1 - 5.6e-66 222.9 0.4 6.1e-66 222.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) USP7_ICP0_bdg PF12436.8 KFP17263.1 - 1.1e-74 250.8 0.0 8.7e-74 247.8 0.0 2.3 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFP17263.1 - 4.7e-65 219.2 4.4 2.1e-62 210.5 2.9 3.1 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFP17263.1 - 6.7e-50 170.0 0.3 1.2e-49 169.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP17263.1 - 8.4e-18 65.0 0.0 2.8e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFP17263.1 - 6e-16 58.6 1.8 7.4e-15 55.1 0.2 2.9 2 1 1 3 3 3 1 MATH domain CSD PF00313.22 KFP17266.1 - 3.5e-13 49.2 0.0 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KFP17266.1 - 0.0094 15.6 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain PMM PF03332.13 KFP17267.1 - 5.8e-111 369.6 1.2 6.5e-111 369.4 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMEM223 PF14640.6 KFP17268.1 - 3.8e-07 30.4 0.1 4.2e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 COX7a PF02238.15 KFP17268.1 - 7 7.1 7.5 0.43 11.0 1.7 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Methyltransf_16 PF10294.9 KFP17269.1 - 1.7e-21 76.7 0.5 1e-19 70.9 0.5 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP17269.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP17269.1 - 0.022 15.4 0.1 0.076 13.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFP17269.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Claudin_2 PF13903.6 KFP17270.1 - 1.7e-18 67.1 6.9 2e-18 66.9 6.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP17270.1 - 1.8e-07 31.2 5.5 2.5e-07 30.7 5.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family AA_permease_C PF13906.6 KFP17270.1 - 0.028 14.5 3.3 0.028 14.5 3.3 2.3 2 0 0 2 2 2 0 C-terminus of AA_permease PsbN PF02468.15 KFP17270.1 - 1.1 9.2 4.5 0.86 9.5 2.1 2.1 1 1 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Acyltransferase PF01553.21 KFP17276.1 - 2.8e-08 33.5 0.0 9.9e-08 31.7 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KFP17276.1 - 8e-05 21.7 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PLAT PF01477.23 KFP17277.1 - 5.7e-19 68.8 0.0 9.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain DCX PF03607.17 KFP17278.1 - 1.5e-36 124.3 0.0 1.4e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Ribosomal_L27A PF00828.19 KFP17279.1 - 4.3e-28 98.5 0.0 5.9e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_2 PF02230.16 KFP17280.1 - 6.3e-17 62.1 0.1 6.7e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_2 PF02230.16 KFP17281.1 - 2.1e-19 70.2 0.0 2.1e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TFIIS_M PF07500.14 KFP17282.1 - 2.4e-37 127.9 2.1 2.4e-37 127.9 2.1 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFP17282.1 - 2.8e-19 68.7 8.0 6.5e-19 67.5 8.0 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFP17282.1 - 3.6e-16 58.9 1.9 1.1e-15 57.4 1.9 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DBD_Tnp_Mut PF03108.15 KFP17282.1 - 0.0019 18.2 0.2 0.0045 16.9 0.2 1.6 1 0 0 1 1 1 1 MuDR family transposase tRNA_synt_1c_R2 PF04557.15 KFP17282.1 - 2.5 9.1 9.0 0.62 11.0 1.4 2.9 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ku_C PF03730.14 KFP17282.1 - 3.4 8.4 8.7 0.22 12.3 2.0 2.4 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm RGS PF00615.19 KFP17283.1 - 5.2e-35 120.3 1.4 7.2e-35 119.8 1.4 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain V-ATPase_H_N PF03224.14 KFP17284.1 - 1.1e-104 350.1 6.9 1.1e-104 350.1 6.9 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFP17284.1 - 4.8e-29 100.8 0.0 4.8e-29 100.8 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 KFP17284.1 - 3.1e-07 30.2 0.1 0.00045 20.2 0.0 4.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2326 PF10088.9 KFP17284.1 - 0.012 15.4 0.1 0.038 13.7 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) UCH PF00443.29 KFP17284.1 - 0.045 13.2 1.6 0.066 12.7 1.6 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase YlbD_coat PF14071.6 KFP17284.1 - 0.14 12.5 5.8 0.035 14.3 1.8 2.0 2 0 0 2 2 2 0 Putative coat protein Muted PF14942.6 KFP17284.1 - 0.34 11.2 7.8 0.3 11.4 1.7 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein 7tm_1 PF00001.21 KFP17285.1 - 1.3e-59 201.7 21.7 1.5e-59 201.4 21.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP17285.1 - 2.2e-09 37.1 13.9 2.8e-09 36.7 13.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP17285.1 - 2.6e-06 27.0 21.2 3.1e-06 26.8 21.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP17285.1 - 0.014 15.1 21.2 0.019 14.6 19.8 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Saf_2TM PF18303.1 KFP17285.1 - 0.5 10.0 5.2 0.094 12.3 0.9 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ATG11 PF10377.9 KFP17286.1 - 1.7e-25 89.6 0.0 1.7e-25 89.6 0.0 5.6 6 2 1 7 7 7 1 Autophagy-related protein 11 TBK1_ULD PF18396.1 KFP17286.1 - 0.0019 18.1 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain NPBW PF15180.6 KFP17286.1 - 3.2 7.6 6.2 0.82 9.5 1.1 2.7 2 0 0 2 2 2 0 Neuropeptides B and W MYT1 PF08474.11 KFP17287.1 - 8.2e-86 287.9 6.8 8.2e-86 287.9 6.8 2.3 2 0 0 2 2 2 1 Myelin transcription factor 1 zf-C2HC PF01530.18 KFP17287.1 - 1.8e-82 271.1 80.1 1.1e-15 57.5 7.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2HC type DUF1664 PF07889.12 KFP17287.1 - 0.029 14.4 0.7 0.13 12.3 0.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KFP17287.1 - 0.069 13.8 3.9 0.31 11.7 3.9 2.1 1 0 0 1 1 1 0 SlyX Prefoldin PF02996.17 KFP17287.1 - 0.26 11.2 5.1 0.17 11.8 2.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 KFP17287.1 - 0.34 9.4 6.6 0.25 9.9 4.5 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-RAG1 PF10426.9 KFP17287.1 - 0.45 10.7 8.2 10 6.4 0.0 5.4 5 0 0 5 5 5 0 Recombination-activating protein 1 zinc-finger domain ADIP PF11559.8 KFP17287.1 - 0.6 10.2 13.5 0.048 13.8 4.1 3.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KFP17287.1 - 8.4 7.1 14.2 0.072 13.7 3.6 3.0 3 0 0 3 3 3 0 Initiation control protein YabA PCMT PF01135.19 KFP17288.1 - 1.6e-28 99.9 0.0 2.2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.16 KFP17288.1 - 1e-06 29.0 1.2 0.011 16.1 0.8 2.6 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.13 KFP17288.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KFP17288.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFP17288.1 - 0.0065 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KFP17288.1 - 0.014 16.1 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RVT_1 PF00078.27 KFP17289.1 - 0.035 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TLV_coat PF00429.19 KFP17290.1 - 0.00092 18.0 0.2 0.00099 17.9 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) RVT_1 PF00078.27 KFP17291.1 - 0.0038 16.8 0.0 0.0073 15.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDZ PF00595.24 KFP17292.1 - 3.3e-17 62.6 0.7 5.9e-17 61.8 0.7 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP17292.1 - 8.7e-08 31.9 0.1 2.5e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 KFP17292.1 - 0.0011 19.5 4.1 1.3 9.5 0.2 3.3 2 1 1 3 3 3 2 PH domain Tricorn_PDZ PF14685.6 KFP17292.1 - 0.13 12.2 0.1 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_2 PF13180.6 KFP17292.1 - 0.17 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PPDFL PF15060.6 KFP17293.1 - 1.4e-06 28.7 1.9 1.1e-05 25.9 1.9 1.9 1 1 0 1 1 1 1 Differentiation and proliferation regulator zf-C2H2 PF00096.26 KFP17294.1 - 9e-28 95.2 32.3 2.8e-06 27.4 1.3 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17294.1 - 4.1e-21 73.8 32.1 6.1e-05 23.5 1.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP17294.1 - 2.2e-19 68.9 33.0 4.7e-08 33.1 0.5 5.9 5 1 0 5 5 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP17294.1 - 1.6e-14 53.7 26.4 0.00052 20.2 0.1 6.4 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP17294.1 - 1.6e-10 40.7 29.4 0.0012 18.8 0.7 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP17294.1 - 1.7e-08 34.5 26.2 0.0034 17.7 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP17294.1 - 6.6e-08 32.7 17.1 0.0042 17.3 2.9 3.5 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KFP17294.1 - 5.2e-05 23.0 16.0 1.1 9.2 1.1 5.4 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-BED PF02892.15 KFP17294.1 - 0.0047 16.9 29.8 0.3 11.2 0.2 5.6 3 1 2 6 6 5 2 BED zinc finger zf-C2H2_2 PF12756.7 KFP17294.1 - 0.0059 16.9 22.2 1.8 8.9 0.3 5.1 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 KFP17294.1 - 0.0067 16.5 18.3 0.019 15.0 0.8 3.2 2 1 1 3 3 3 1 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 KFP17294.1 - 0.0068 17.1 1.0 0.0068 17.1 1.0 2.9 2 1 0 2 2 1 1 zinc-ribbon family PyrI_C PF02748.15 KFP17294.1 - 0.038 13.9 17.1 2.8 7.9 1.6 4.9 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.6 KFP17294.1 - 0.039 13.7 0.6 0.039 13.7 0.6 5.6 5 1 0 5 5 4 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KFP17294.1 - 0.064 13.4 22.4 0.55 10.4 2.1 4.3 3 1 0 3 3 3 0 Zinc ribbon domain Trm112p PF03966.16 KFP17294.1 - 0.25 12.0 2.1 12 6.5 0.5 3.6 3 1 0 3 3 3 0 Trm112p-like protein DUF4764 PF15961.5 KFP17294.1 - 0.25 10.0 6.3 0.73 8.4 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf_UBZ PF18439.1 KFP17294.1 - 0.49 10.0 16.1 17 5.1 0.1 5.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 KFP17294.1 - 0.76 10.0 26.1 8.5 6.6 1.9 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zf_ZIC PF18366.1 KFP17294.1 - 0.93 9.6 14.3 13 6.0 1.5 4.9 2 2 3 5 5 5 0 Zic proteins zinc finger domain zinc_ribbon_9 PF14369.6 KFP17294.1 - 1.1 9.6 9.3 0.72 10.2 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon zf-LYAR PF08790.11 KFP17294.1 - 1.8 8.5 12.9 6.1 6.9 0.2 4.8 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-CHY PF05495.12 KFP17294.1 - 2.2 8.8 24.9 0.41 11.2 4.9 2.6 2 1 0 2 2 2 0 CHY zinc finger Ogr_Delta PF04606.12 KFP17294.1 - 3.4 7.7 12.5 0.058 13.4 3.7 2.6 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 KFP17294.1 - 4.2 7.4 26.7 0.079 12.9 5.8 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain Voltage_CLC PF00654.20 KFP17295.1 - 3.8e-22 79.0 8.7 4.3e-22 78.8 8.7 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel UQ_con PF00179.26 KFP17296.1 - 2e-18 66.4 0.0 2.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP17296.1 - 0.032 14.5 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain MCM PF00493.23 KFP17297.1 - 2.8e-99 330.8 0.0 4e-99 330.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP17297.1 - 4.6e-40 136.4 0.3 8.2e-40 135.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFP17297.1 - 2.2e-26 92.1 1.1 8.4e-26 90.2 1.1 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFP17297.1 - 7.5e-19 68.2 3.7 1.8e-18 67.0 1.1 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFP17297.1 - 3.2e-08 33.2 0.0 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFP17297.1 - 3.3e-08 33.6 0.1 3.8e-07 30.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFP17297.1 - 2.9e-05 24.0 0.0 6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDT1_C PF16679.5 KFP17297.1 - 0.01 16.3 2.0 0.019 15.4 0.4 2.3 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Sigma54_activat PF00158.26 KFP17297.1 - 0.011 15.5 0.0 2.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KFP17297.1 - 0.017 15.5 0.0 0.062 13.7 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KFP17297.1 - 0.092 12.7 1.1 5.4 6.9 0.0 3.0 3 1 1 4 4 4 0 NTPase DUF1178 PF06676.11 KFP17297.1 - 0.52 10.7 2.1 1.1 9.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1178) AAA_22 PF13401.6 KFP17297.1 - 0.93 9.8 3.1 11 6.3 0.0 3.2 2 2 2 4 4 4 0 AAA domain CRISPR_Cse2 PF09485.10 KFP17297.1 - 1.1 9.8 4.5 1.5 9.4 1.6 2.7 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) NUC194 PF08163.12 KFP17298.1 - 1.1e-161 538.1 1.9 2.1e-161 537.2 1.9 1.5 1 0 0 1 1 1 1 NUC194 domain Tubulin PF00091.25 KFP17299.1 - 2.2e-22 80.2 0.0 2.4e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.25 KFP17300.1 - 3.1e-42 145.0 0.0 4.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP17300.1 - 5.1e-21 75.2 0.0 8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP17300.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFP17300.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin like DUF3974 PF13120.6 KFP17301.1 - 0.0078 16.3 0.1 0.0078 16.3 0.1 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3974) PAC4 PF16093.5 KFP17301.1 - 0.088 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Sugar_tr PF00083.24 KFP17302.1 - 1.1e-19 70.7 16.7 1.5e-19 70.2 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP17302.1 - 4.7e-11 42.2 24.9 1.9e-06 27.0 12.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sre PF03125.18 KFP17302.1 - 0.066 12.3 3.3 2.5 7.1 1.8 2.5 2 0 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor PX PF00787.24 KFP17304.1 - 0.091 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 PX domain Pkinase PF00069.25 KFP17305.1 - 6.5e-49 166.7 0.7 6.5e-49 166.7 0.7 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17305.1 - 9.6e-23 80.8 0.1 3e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFP17305.1 - 0.0012 18.0 0.3 0.002 17.2 0.3 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ECH_1 PF00378.20 KFP17306.1 - 2.1e-41 141.9 0.0 3.4e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 KFP17306.1 - 1.1e-28 99.3 0.5 2e-28 98.4 0.5 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 KFP17306.1 - 7.1e-18 65.2 0.0 2.5e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase TPR_21 PF09976.9 KFP17306.1 - 0.011 15.4 1.7 1 9.0 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ECH_1 PF00378.20 KFP17309.1 - 1.6e-32 112.8 0.0 2.4e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 KFP17309.1 - 1.8e-18 66.2 3.7 4.4e-18 64.9 3.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 KFP17309.1 - 5.8e-17 62.2 1.0 9.7e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Mtf2_C PF14061.6 KFP17309.1 - 0.012 15.8 0.2 0.023 14.9 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 KFP17309.1 - 5.2 7.0 8.5 0.28 11.1 0.8 2.7 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain Ribonuc_P_40 PF08584.11 KFP17310.1 - 5.1e-94 314.7 0.0 5.8e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Complex1_LYR PF05347.15 KFP17312.1 - 3.2e-11 43.1 1.9 3.4e-11 43.0 1.9 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFP17312.1 - 0.00011 22.9 0.6 0.00011 22.9 0.6 1.0 1 0 0 1 1 1 1 Complex1_LYR-like DUF4462 PF14692.6 KFP17313.1 - 0.072 12.6 1.5 0.84 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) tRNA-synt_2d PF01409.20 KFP17315.1 - 2.2e-48 164.9 2.5 4.3e-30 105.0 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KFP17315.1 - 7.6e-22 77.6 0.0 2.8e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 KFP17315.1 - 0.013 14.6 0.0 1.8 7.5 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Transglut_N PF00868.20 KFP17316.1 - 1.8e-34 118.6 0.3 1.8e-33 115.4 0.0 2.7 3 1 1 4 4 4 1 Transglutaminase family Transglut_C PF00927.22 KFP17316.1 - 5.4e-28 97.2 0.5 3e-14 53.0 0.1 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP17316.1 - 4.9e-17 62.4 0.2 1.1e-16 61.2 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily E1_DerP2_DerF2 PF02221.15 KFP17317.1 - 2.3e-08 34.6 0.2 3.1e-08 34.1 0.2 1.2 1 0 0 1 1 1 1 ML domain Rib_hydrolayse PF02267.17 KFP17317.1 - 0.066 12.6 0.1 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosyl cyclase DUF3324 PF11797.8 KFP17317.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) zf-C2H2 PF00096.26 KFP17319.1 - 6.8e-43 142.8 123.8 7.9e-05 22.9 2.5 16.2 16 0 0 16 16 16 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17319.1 - 6.1e-39 129.3 117.0 0.00045 20.8 1.1 16.0 16 0 0 16 16 16 15 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP17319.1 - 3.8e-26 90.3 114.1 5e-08 33.0 1.1 19.5 20 0 0 20 20 20 7 Zinc-finger double domain zf-met PF12874.7 KFP17319.1 - 1.4e-11 44.4 75.2 0.012 15.9 0.4 13.1 13 0 0 13 13 13 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP17319.1 - 7.8e-09 35.6 52.6 0.064 13.6 1.5 12.9 14 0 0 14 14 14 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP17319.1 - 6.8e-08 32.3 99.1 4.9e-06 26.4 0.2 15.1 17 0 0 17 17 17 6 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP17319.1 - 1.4e-07 31.1 68.8 2.4e-07 30.4 0.0 11.6 12 0 0 12 12 12 5 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFP17319.1 - 0.0034 17.6 5.1 0.0034 17.6 5.1 9.3 7 4 3 10 10 10 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP17319.1 - 0.012 15.8 0.8 0.012 15.8 0.8 6.4 7 0 0 7 7 7 0 C2H2-type zinc ribbon BolA PF01722.18 KFP17319.1 - 3.3 8.1 12.4 61 4.0 0.7 6.2 7 1 0 7 7 7 0 BolA-like protein TRAP_alpha PF03896.16 KFP17321.1 - 5.4e-110 367.1 1.3 5.8e-110 367.0 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit RIO1 PF01163.22 KFP17322.1 - 2.2e-75 252.4 0.2 2.2e-75 252.4 0.2 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFP17322.1 - 0.011 15.7 0.0 0.1 12.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tnp_P_element_C PF12596.8 KFP17322.1 - 6.3 7.4 10.4 0.14 12.8 0.8 3.0 3 1 0 3 3 3 0 87kDa Transposase Plectin PF00681.20 KFP17323.1 - 1.5e-129 421.6 7.9 9.3e-17 60.6 0.1 14.3 12 2 2 14 14 14 11 Plectin repeat Spectrin_like PF18373.1 KFP17323.1 - 4.9e-32 109.8 2.1 4.9e-32 109.8 2.1 5.7 6 0 0 6 6 6 1 Spectrin like domain SH3_10 PF17902.1 KFP17323.1 - 3.7e-19 68.6 0.0 1.4e-18 66.7 0.0 2.1 1 0 0 1 1 1 1 SH3 domain SOGA PF11365.8 KFP17323.1 - 0.0023 19.0 8.6 0.0023 19.0 8.6 14.0 4 1 10 16 16 16 2 Protein SOGA CLP_protease PF00574.23 KFP17323.1 - 1.7 8.5 7.0 3.9 7.3 0.0 5.3 5 0 0 5 5 5 0 Clp protease Thioredoxin PF00085.20 KFP17325.1 - 2.8e-81 268.1 0.0 4.9e-29 100.4 0.0 3.0 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 KFP17325.1 - 9.5e-13 48.6 1.1 0.0042 17.5 0.0 3.5 3 1 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 KFP17325.1 - 5.1e-12 45.7 0.1 0.0035 16.7 0.0 3.1 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFP17325.1 - 2.8e-08 34.0 0.4 1 9.7 0.0 5.2 3 3 2 5 5 5 3 Thioredoxin-like HyaE PF07449.11 KFP17325.1 - 1.3e-06 28.3 0.0 0.0069 16.3 0.0 3.0 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KFP17325.1 - 0.00038 20.3 9.3 0.16 11.8 0.0 4.4 3 2 2 5 5 5 2 F plasmid transfer operon protein AhpC-TSA PF00578.21 KFP17325.1 - 0.00082 19.3 0.6 0.89 9.5 0.0 2.5 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KFP17325.1 - 0.0023 18.0 1.3 8.3 6.7 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KFP17325.1 - 0.012 15.4 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Muted PF14942.6 KFP17326.1 - 5.1e-34 117.7 20.4 5.6e-34 117.6 20.4 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF148 PF02520.17 KFP17326.1 - 0.028 14.5 8.8 0.17 12.0 5.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 YkyA PF10368.9 KFP17326.1 - 0.046 13.4 16.1 0.066 12.9 16.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein FliD_C PF07195.12 KFP17326.1 - 0.082 12.3 6.3 0.16 11.4 6.3 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF802 PF05650.11 KFP17326.1 - 0.17 12.4 1.4 0.2 12.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Tox-REase-2 PF15646.6 KFP17326.1 - 0.22 11.7 3.4 1 9.5 0.3 2.2 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 EcsC PF12787.7 KFP17326.1 - 0.31 10.7 9.0 1.3 8.6 9.1 1.8 1 1 0 1 1 1 0 EcsC protein family T3SSipB PF16535.5 KFP17326.1 - 0.78 10.2 7.0 4.4 7.8 2.9 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB Aldedh PF00171.22 KFP17326.1 - 0.85 8.0 5.9 1 7.8 5.9 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family FCH PF00611.23 KFP17326.1 - 0.9 9.9 8.8 0.26 11.6 5.5 1.9 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TMPIT PF07851.13 KFP17326.1 - 1.2 8.3 9.5 1.4 8.1 9.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 KFP17326.1 - 1.4 9.1 8.9 2.7 8.2 8.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KFP17326.1 - 1.4 7.3 3.5 1.5 7.2 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KFP17326.1 - 3.3 5.5 12.0 3.9 5.3 12.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.20 KFP17326.1 - 4.5 5.3 10.3 5.3 5.1 10.3 1.1 1 0 0 1 1 1 0 Hsp70 protein AAA_11 PF13086.6 KFP17326.1 - 5 6.8 11.6 5.5 6.7 11.6 1.0 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KFP17326.1 - 5.8 6.4 10.6 6.8 6.2 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GST_C PF00043.25 KFP17327.1 - 2.3e-07 30.9 0.2 4.9e-07 29.9 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP17327.1 - 0.00014 22.0 0.1 0.00021 21.4 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP17327.1 - 0.0014 18.7 0.0 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain UAA PF08449.11 KFP17329.1 - 4.5e-96 321.6 24.1 5.4e-96 321.4 24.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFP17329.1 - 0.0035 17.5 31.3 0.0056 16.9 16.1 2.6 2 1 1 3 3 3 2 EamA-like transporter family TLV_coat PF00429.19 KFP17331.1 - 4.3e-109 365.7 1.0 4.8e-109 365.6 1.0 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) PSII_Ycf12 PF05969.11 KFP17331.1 - 0.013 15.4 1.1 0.035 14.1 1.1 1.7 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 SlyX PF04102.12 KFP17331.1 - 0.2 12.3 1.9 0.36 11.5 0.1 2.3 2 1 1 3 3 3 0 SlyX OFCC1 PF15680.5 KFP17334.1 - 9.2e-60 200.0 3.2 1.3e-59 199.5 3.2 1.2 1 0 0 1 1 1 1 Orofacial cleft 1 candidate gene 1 protein DUF3674 PF12426.8 KFP17334.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase Branch PF02485.21 KFP17337.1 - 2e-31 109.4 0.0 2.3e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Tmemb_14 PF03647.13 KFP17338.1 - 1.6e-17 64.0 2.6 1.8e-17 63.8 2.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C ETRAMP PF09716.10 KFP17338.1 - 0.45 10.6 2.3 5.6 7.1 0.3 2.6 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 KFP17339.1 - 1.1e-76 257.7 0.0 1.4e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17339.1 - 7.1e-36 123.8 0.2 3.5e-35 121.5 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Fox-1_C PF12414.8 KFP17340.1 - 1.9e-43 146.7 22.8 1.9e-43 146.7 22.8 2.6 3 1 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.22 KFP17340.1 - 1.5e-18 66.3 0.1 3.4e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPESP1 PF15754.5 KFP17340.1 - 0.016 14.4 3.6 0.024 13.8 3.6 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 RRM_5 PF13893.6 KFP17340.1 - 0.054 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tektin PF03148.14 KFP17342.1 - 1.1e-139 465.5 29.7 1.2e-139 465.3 29.7 1.0 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.12 KFP17342.1 - 0.23 11.5 6.7 0.54 10.3 0.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Z1 PF10593.9 KFP17342.1 - 1.4 8.4 6.1 0.38 10.2 0.4 2.6 1 1 2 3 3 3 0 Z1 domain TMF_DNA_bd PF12329.8 KFP17342.1 - 1.9 8.5 23.1 0.25 11.4 0.9 3.9 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Myc-LZ PF02344.15 KFP17342.1 - 2.1 8.5 14.5 4.3 7.5 1.2 4.2 4 0 0 4 4 4 0 Myc leucine zipper domain Fib_alpha PF08702.10 KFP17342.1 - 2.3 8.4 15.5 2.8 8.1 0.3 3.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP17342.1 - 2.6 8.1 11.5 1.2 9.2 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) C1q PF00386.21 KFP17343.1 - 4.4e-36 123.9 1.9 5.5e-36 123.6 1.9 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP17343.1 - 3e-08 33.3 14.1 4.6e-08 32.7 14.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) GbpA_2 PF18416.1 KFP17343.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 HMG_box PF00505.19 KFP17344.1 - 6.1e-05 23.4 1.0 0.0001 22.7 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box LMF1 PF06762.14 KFP17345.1 - 2.1e-146 488.5 11.3 4.5e-76 256.8 7.4 2.1 1 1 0 2 2 2 2 Lipase maturation factor G-gamma PF00631.22 KFP17347.1 - 8.7e-13 48.1 0.2 9.1e-13 48.0 0.2 1.0 1 0 0 1 1 1 1 GGL domain CSN4_RPN5_eIF3a PF18420.1 KFP17347.1 - 0.027 14.7 0.3 0.042 14.0 0.3 1.4 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain AAA PF00004.29 KFP17349.1 - 5.3e-13 49.5 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP17349.1 - 7.8e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFP17349.1 - 2.1e-07 31.0 0.1 1.9e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KFP17349.1 - 4.7e-07 29.9 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFP17349.1 - 1.1e-05 25.5 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP17349.1 - 0.0001 22.5 0.0 0.00028 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP17349.1 - 0.00018 22.0 0.0 0.0035 17.7 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFP17349.1 - 0.00019 21.7 0.1 0.0018 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP17349.1 - 0.00033 21.2 0.0 0.00083 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFP17349.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFP17349.1 - 0.0022 17.5 0.0 0.006 16.1 0.0 1.7 2 1 1 3 3 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KFP17349.1 - 0.005 16.1 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KFP17349.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFP17349.1 - 0.0064 15.7 0.0 0.0086 15.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 KFP17349.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFP17349.1 - 0.0079 16.1 0.3 0.17 11.8 0.0 2.3 1 1 0 2 2 2 1 NTPase RsgA_GTPase PF03193.16 KFP17349.1 - 0.0098 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 KFP17349.1 - 0.01 15.8 0.0 0.13 12.1 0.0 2.2 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.22 KFP17349.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 KFP17349.1 - 0.016 15.5 0.4 0.07 13.4 0.1 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFP17349.1 - 0.016 15.7 0.0 0.04 14.4 0.0 1.7 1 1 1 2 2 1 0 ABC transporter AAA_24 PF13479.6 KFP17349.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFP17349.1 - 0.019 14.4 0.0 0.2 11.1 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 KFP17349.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFP17349.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFP17349.1 - 0.05 13.9 0.5 0.13 12.6 0.1 1.9 2 1 1 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFP17349.1 - 0.064 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFP17349.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KFP17349.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mesothelin PF06060.12 KFP17350.1 - 2.2e-136 455.6 0.1 2.6e-136 455.4 0.1 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Fe_hyd_lg_C PF02906.14 KFP17352.1 - 3e-78 262.8 0.0 4.4e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 KFP17352.1 - 3.7e-09 36.5 0.1 6.8e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.12 KFP17352.1 - 0.00061 19.7 0.4 0.0014 18.6 0.4 1.5 1 0 0 1 1 1 1 FAD synthetase Whirly PF08536.11 KFP17352.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Whirly transcription factor HAGH_C PF16123.5 KFP17353.1 - 1.6e-24 86.2 0.4 2.6e-24 85.5 0.4 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFP17353.1 - 3.7e-08 33.6 2.1 3.1e-07 30.6 2.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFP17353.1 - 0.00028 20.4 0.4 0.00056 19.5 0.4 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HAGH_C PF16123.5 KFP17354.1 - 2.2e-27 95.3 0.6 4.1e-27 94.5 0.2 1.7 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KFP17354.1 - 2.5e-11 44.0 0.6 7.7e-07 29.3 0.3 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFP17354.1 - 0.00057 19.5 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain REPA_OB_2 PF16900.5 KFP17355.1 - 2.4e-07 30.6 0.0 8.3e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 Replication protein A OB domain CDC24_OB3 PF17244.2 KFP17355.1 - 2e-06 27.7 0.6 1.7e-05 24.7 0.8 2.1 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 Sulfotransfer_1 PF00685.27 KFP17356.1 - 3.5e-32 111.9 0.0 4.2e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP17356.1 - 9.4e-12 45.8 0.0 1.3e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 KFP17356.1 - 0.011 15.7 0.0 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family SelR PF01641.18 KFP17357.1 - 3.9e-17 62.5 0.2 4.2e-17 62.3 0.2 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.6 KFP17357.1 - 0.00094 19.6 0.4 0.6 10.7 0.0 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.6 KFP17357.1 - 0.016 14.9 3.2 0.56 10.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KFP17357.1 - 0.031 13.8 0.3 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 KFP17357.1 - 0.032 13.8 1.3 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 KFP17357.1 - 0.034 14.1 3.6 0.32 11.0 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF983 PF06170.12 KFP17357.1 - 0.042 14.3 0.4 4 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TFIIS_C PF01096.18 KFP17357.1 - 0.056 13.3 1.3 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_SprT PF17283.2 KFP17357.1 - 0.077 12.9 0.6 7.6 6.5 0.2 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KFP17357.1 - 0.083 13.0 1.2 1.8 8.7 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KFP17357.1 - 0.19 11.2 4.1 2.8 7.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.11 KFP17357.1 - 0.23 11.5 1.0 5.5 7.0 0.2 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc_ribbon_5 PF13719.6 KFP17357.1 - 0.25 11.2 5.1 2.7 7.8 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KFP17357.1 - 0.59 9.8 4.7 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rubredoxin_2 PF18073.1 KFP17357.1 - 2.5 7.9 5.9 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain MMM1 PF10296.9 KFP17359.1 - 7.5e-08 31.8 0.2 2.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Ribosomal_L3 PF00297.22 KFP17360.1 - 1.4e-180 600.1 14.2 1.6e-180 599.9 14.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RTX PF02382.15 KFP17360.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein NDUFB10 PF10249.9 KFP17361.1 - 4.5e-48 162.9 5.6 4.9e-48 162.8 5.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 WW PF00397.26 KFP17361.1 - 0.16 12.1 1.1 0.3 11.2 1.1 1.5 1 0 0 1 1 1 0 WW domain Ribosomal_S5 PF00333.20 KFP17362.1 - 2.2e-31 107.7 0.4 4.1e-31 106.8 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFP17362.1 - 5.8e-27 93.0 0.0 1e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WD40 PF00400.32 KFP17363.1 - 6.4e-56 185.0 38.2 2.7e-07 31.1 0.4 11.6 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KFP17363.1 - 7.9e-41 139.3 2.2 1.4e-40 138.5 2.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KFP17363.1 - 2.6e-09 37.3 9.1 0.28 11.5 0.0 7.7 3 3 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP17363.1 - 3e-06 26.2 10.3 0.7 8.5 0.1 6.3 4 2 1 5 5 5 3 Nucleoporin Nup120/160 NUP214 PF16755.5 KFP17363.1 - 0.00013 21.3 0.1 0.00064 19.1 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40_like PF17005.5 KFP17363.1 - 0.00079 18.8 0.3 3.5 6.8 0.0 4.6 4 3 2 7 7 7 1 WD40-like domain Ge1_WD40 PF16529.5 KFP17363.1 - 0.0017 17.4 8.1 2 7.3 0.1 5.5 3 3 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFP17363.1 - 0.0022 16.8 3.8 0.87 8.3 0.1 5.0 3 2 3 6 6 6 1 Nup133 N terminal like UTP15_C PF09384.10 KFP17363.1 - 0.012 15.3 2.9 0.02 14.6 2.9 1.3 1 0 0 1 1 1 0 UTP15 C terminal LRRC37AB_C PF14914.6 KFP17363.1 - 0.017 15.0 0.9 0.031 14.2 0.9 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CP12 PF02672.15 KFP17363.1 - 0.41 11.4 2.2 5.5 7.8 0.6 2.8 2 0 0 2 2 2 0 CP12 domain SH3_9 PF14604.6 KFP17364.1 - 3.4e-15 55.6 0.0 4.5e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP17364.1 - 4e-15 55.1 1.4 5.4e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFP17364.1 - 1.6e-13 50.1 0.0 1.1e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KFP17364.1 - 1.4e-07 31.7 0.7 0.0011 19.2 0.1 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain PX PF00787.24 KFP17364.1 - 2e-07 31.0 0.8 4.3e-07 29.9 0.4 1.8 2 0 0 2 2 2 1 PX domain SH3_4 PF06347.13 KFP17364.1 - 3.6e-05 23.5 0.5 0.00035 20.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain p47_phox_C PF08944.11 KFP17364.1 - 0.00045 19.6 0.8 0.00045 19.6 0.8 1.9 2 0 0 2 2 2 1 NADPH oxidase subunit p47Phox, C terminal domain Evr1_Alr PF04777.13 KFP17365.1 - 1.6e-22 79.9 1.4 1.8e-22 79.7 1.4 1.0 1 0 0 1 1 1 1 Erv1 / Alr family DUF3970 PF13113.6 KFP17365.1 - 0.0042 17.3 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3970) FAD_SOX PF18371.1 KFP17365.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MARVEL PF01284.23 KFP17366.1 - 9.2e-19 67.9 13.5 1.1e-18 67.6 13.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1129 PF06570.11 KFP17366.1 - 0.074 12.5 1.2 0.074 12.5 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) PEN-2 PF10251.9 KFP17366.1 - 0.8 10.2 6.1 0.24 11.8 2.5 1.9 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase zf-C2H2 PF00096.26 KFP17367.1 - 0.0056 17.1 0.7 0.0056 17.1 0.7 5.8 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17367.1 - 0.025 15.4 0.2 0.025 15.4 0.2 6.8 6 1 0 6 6 6 0 C2H2-type zinc finger EBP50_C PF09007.11 KFP17368.1 - 1.8e-28 100.1 4.6 1.2e-25 90.9 3.9 2.8 2 1 0 2 2 2 1 EBP50, C-terminal PDZ_6 PF17820.1 KFP17368.1 - 2.1e-27 94.7 4.3 3.4e-16 58.8 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFP17368.1 - 1.9e-23 82.6 0.5 8.1e-14 51.7 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP17368.1 - 1.5e-11 44.5 1.0 7.3e-06 26.2 0.0 3.5 3 1 0 3 3 3 2 PDZ domain GRASP55_65 PF04495.14 KFP17368.1 - 0.034 14.5 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Ribosomal_S17e PF00833.18 KFP17368.1 - 2.7 7.9 5.9 3.7 7.5 0.3 2.6 3 0 0 3 3 3 0 Ribosomal S17 HhH-GPD PF00730.25 KFP17369.1 - 3.4e-20 72.5 0.0 5.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFP17369.1 - 1.6e-09 37.2 0.0 2.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFP17369.1 - 0.025 15.2 0.0 0.59 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Tuberin PF03542.16 KFP17370.1 - 4.1e-140 466.9 6.4 4.1e-140 466.9 6.4 2.6 3 0 0 3 3 3 1 Tuberin DUF3384 PF11864.8 KFP17370.1 - 7.8e-96 321.9 10.4 7.8e-96 321.9 10.4 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KFP17370.1 - 3.5e-42 144.0 0.0 7e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Cnd1 PF12717.7 KFP17370.1 - 0.031 14.3 5.2 0.038 14.0 0.2 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Telomere_reg-2 PF10193.9 KFP17370.1 - 0.12 12.8 1.8 0.38 11.2 0.4 2.7 2 0 0 2 2 2 0 Telomere length regulation protein HEAT PF02985.22 KFP17370.1 - 0.13 12.6 0.1 2.7 8.5 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat PKD PF00801.20 KFP17371.1 - 1.4e-157 511.8 93.3 3e-15 55.8 0.2 17.3 18 0 0 18 18 18 15 PKD domain REJ PF02010.15 KFP17371.1 - 2.4e-102 343.1 0.1 1.7e-100 337.0 0.0 3.1 3 0 0 3 3 3 1 REJ domain PKD_channel PF08016.12 KFP17371.1 - 5.2e-88 295.6 18.1 7.9e-88 295.0 18.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel PLAT PF01477.23 KFP17371.1 - 4.3e-22 78.9 0.1 1.7e-21 76.9 0.1 2.1 1 0 0 1 1 1 1 PLAT/LH2 domain Lectin_C PF00059.21 KFP17371.1 - 3.3e-11 43.9 3.0 3.5e-11 43.8 0.4 2.6 3 0 0 3 3 1 1 Lectin C-type domain LRR_8 PF13855.6 KFP17371.1 - 6.6e-11 41.8 5.0 1.8e-10 40.4 5.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat Y_Y_Y PF07495.13 KFP17371.1 - 2e-10 40.5 17.0 0.0016 18.3 0.0 7.5 8 0 0 8 8 7 3 Y_Y_Y domain WSC PF01822.19 KFP17371.1 - 0.00031 20.9 7.4 0.00073 19.7 7.4 1.7 1 0 0 1 1 1 1 WSC domain Ion_trans PF00520.31 KFP17371.1 - 0.00048 19.4 19.8 0.0014 17.9 19.8 1.8 1 0 0 1 1 1 1 Ion transport protein LRR_4 PF12799.7 KFP17371.1 - 0.0022 18.4 2.1 0.0022 18.4 2.1 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) GPS PF01825.21 KFP17371.1 - 0.0079 16.7 0.0 0.035 14.6 0.0 2.2 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRRCT PF01463.24 KFP17371.1 - 0.035 14.7 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DUF1727 PF08353.10 KFP17371.1 - 0.088 12.7 0.1 21 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1727) LRR_5 PF13306.6 KFP17371.1 - 0.11 12.4 0.6 0.55 10.2 0.4 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) VirB3 PF05101.13 KFP17371.1 - 7.1 6.9 9.4 0.28 11.4 0.5 3.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein PKD_3 PF16820.5 KFP17371.1 - 9.4 6.1 19.4 31 4.4 0.1 7.6 7 0 0 7 7 7 0 PKD-like domain IL8 PF00048.20 KFP17372.1 - 2.5e-18 66.0 0.9 3e-18 65.7 0.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ig_J_chain PF15097.6 KFP17372.1 - 0.063 13.2 0.1 0.083 12.8 0.1 1.1 1 0 0 1 1 1 0 Immunoglobulin J chain IL8 PF00048.20 KFP17373.1 - 2.8e-14 53.0 0.2 3.4e-14 52.7 0.2 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like bPH_6 PF10756.9 KFP17373.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain IL8 PF00048.20 KFP17374.1 - 1.2e-15 57.4 0.1 1.6e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like RA PF00788.23 KFP17375.1 - 4.1e-12 46.6 0.0 9.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KFP17375.1 - 2.7e-10 40.0 1.8 7.6e-10 38.5 1.8 1.8 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain GN3L_Grn1 PF08701.11 KFP17375.1 - 0.096 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Ras_bdg_2 PF14847.6 KFP17375.1 - 0.1 12.9 2.2 1.8 8.9 1.0 2.8 2 1 0 2 2 2 0 Ras-binding domain of Byr2 Serum_albumin PF00273.20 KFP17376.1 - 1e-149 494.4 32.8 3.6e-56 189.7 12.7 3.1 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.10 KFP17376.1 - 2.3e-06 27.5 13.5 0.0017 18.3 1.1 4.9 4 0 0 4 4 4 3 Vitamin D binding protein, domain III ThiP_synth PF10120.9 KFP17376.1 - 0.19 11.3 0.0 0.52 9.9 0.0 1.7 1 0 0 1 1 1 0 Thiamine-phosphate synthase Hydrolase_4 PF12146.8 KFP17377.1 - 3.9e-14 52.5 0.0 1.9e-07 30.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP17377.1 - 1e-08 35.2 0.1 0.0012 18.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFP17377.1 - 1.6e-07 31.0 0.0 1.3e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFP17377.1 - 4.7e-07 30.6 0.0 5.1e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KFP17377.1 - 0.00047 19.8 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KFP17377.1 - 0.0008 19.4 0.0 0.0087 16.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF818 PF05677.12 KFP17377.1 - 0.00089 18.3 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Asp2 PF16929.5 KFP17377.1 - 0.0024 16.9 0.0 0.0031 16.6 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter FSH1 PF03959.13 KFP17377.1 - 0.0034 17.1 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFP17377.1 - 0.0065 16.3 0.0 0.054 13.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KFP17377.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KFP17377.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) EloA-BP1 PF15870.5 KFP17378.1 - 4.2e-73 245.0 0.2 4.2e-73 245.0 0.2 3.5 2 1 0 2 2 2 1 ElonginA binding-protein 1 RNase_T PF00929.24 KFP17378.1 - 9.1e-07 29.6 0.2 3.9e-05 24.2 0.1 2.6 2 1 0 2 2 2 1 Exonuclease Homeodomain PF00046.29 KFP17379.1 - 2.1e-11 43.5 1.4 3.2e-11 42.9 1.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP17379.1 - 2.4e-05 24.2 0.3 5.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Homeobox KN domain LRR_8 PF13855.6 KFP17380.1 - 1.6e-52 175.1 78.4 1.3e-16 60.1 2.1 6.7 2 2 6 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 KFP17380.1 - 2.8e-18 66.1 0.0 3.4e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP17380.1 - 1.3e-15 57.3 50.0 2.5e-05 24.5 0.8 7.9 6 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP17380.1 - 1e-06 28.5 34.7 4.2 8.3 0.0 11.0 10 2 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 KFP17380.1 - 4.1e-05 23.2 12.5 0.44 10.0 1.9 4.1 2 2 2 4 4 4 3 Leucine-rich repeat LRRNT PF01462.18 KFP17380.1 - 0.009 15.6 1.8 0.009 15.6 1.8 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain MCLC PF05934.11 KFP17380.1 - 0.25 10.0 0.1 0.38 9.4 0.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Nramp PF01566.18 KFP17381.1 - 2.8e-104 349.0 18.6 1.4e-101 340.1 18.6 2.0 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein G-alpha PF00503.20 KFP17382.1 - 1.6e-114 382.8 3.5 1.8e-114 382.6 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP17382.1 - 6.6e-14 51.7 0.6 6.2e-13 48.6 0.1 2.6 2 1 1 3 3 3 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP17383.1 - 7.9e-123 410.1 0.5 9.4e-123 409.9 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP17383.1 - 2.6e-16 59.6 2.0 5.9e-11 42.1 0.1 2.8 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP17383.1 - 0.00057 19.3 0.6 0.41 10.0 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP17383.1 - 0.0022 18.2 0.2 2.1 8.6 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 KFP17383.1 - 0.0079 15.4 0.6 0.013 14.7 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 KFP17383.1 - 0.073 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KFP17383.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP17383.1 - 0.18 12.2 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GST_N PF02798.20 KFP17384.1 - 1.6e-17 63.6 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP17384.1 - 0.0031 17.9 0.0 0.0075 16.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain SeqA_N PF17206.3 KFP17384.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain AdoHcyase PF05221.17 KFP17385.1 - 1.8e-29 102.8 0.1 1e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase TP2 PF01254.18 KFP17385.1 - 0.033 14.8 2.8 0.044 14.4 2.8 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 SR-25 PF10500.9 KFP17385.1 - 0.19 11.3 6.8 0.24 11.0 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 KFP17385.1 - 4.3 5.6 6.7 5.8 5.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3402 PF11882.8 KFP17386.1 - 6.5e-102 342.0 18.5 1.6e-65 222.1 5.6 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) N1221 PF07923.13 KFP17386.1 - 7.5e-29 100.8 0.0 7e-27 94.4 0.0 2.3 2 0 0 2 2 2 2 N1221-like protein ELM2 PF01448.24 KFP17386.1 - 0.088 13.6 0.5 0.22 12.3 0.5 1.7 1 0 0 1 1 1 0 ELM2 domain Homeodomain PF00046.29 KFP17387.1 - 4.4e-25 87.3 6.4 5e-25 87.1 6.4 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP17387.1 - 8.1e-05 22.4 0.2 0.00015 21.6 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain SNF PF00209.18 KFP17388.1 - 2.2e-222 739.4 33.4 2.7e-222 739.1 33.4 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Tmemb_18A PF09771.9 KFP17388.1 - 0.12 12.8 1.9 0.6 10.5 0.1 2.8 3 0 0 3 3 3 0 Transmembrane protein 188 Ion_trans PF00520.31 KFP17389.1 - 2.7e-43 147.9 16.3 3.5e-43 147.6 16.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP17389.1 - 1.4e-28 99.1 0.0 3e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP17389.1 - 6.2e-11 42.1 3.1 6.2e-11 42.1 3.1 2.5 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFP17389.1 - 0.00087 19.4 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF202 PF02656.15 KFP17389.1 - 0.75 10.3 7.4 27 5.3 3.4 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Arf PF00025.21 KFP17390.1 - 1.8e-55 187.1 0.1 2.1e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP17390.1 - 5.4e-13 48.8 3.4 1.6e-07 30.8 0.6 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFP17390.1 - 6.8e-12 45.7 0.0 9.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP17390.1 - 5.9e-11 42.2 0.0 6.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP17390.1 - 2.1e-10 40.3 0.1 2.7e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP17390.1 - 3.7e-07 29.7 0.1 4.4e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP17390.1 - 3.8e-07 30.2 0.0 5.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP17390.1 - 0.0013 19.0 0.1 0.025 14.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFP17390.1 - 0.0091 15.5 0.0 0.055 13.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP17390.1 - 0.015 14.9 0.1 0.031 13.8 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP17390.1 - 0.04 13.8 0.2 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KFP17390.1 - 0.06 13.9 0.0 0.099 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFP17390.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Cupin_4 PF08007.12 KFP17392.1 - 1.6e-92 310.4 0.0 2.1e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KFP17392.1 - 3.6e-06 26.9 0.1 0.0094 15.7 0.1 2.3 1 1 1 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 KFP17392.1 - 0.00037 20.1 0.1 0.011 15.5 0.1 2.3 1 1 0 1 1 1 1 Cupin domain Neur_chan_LBD PF02931.23 KFP17393.1 - 2e-51 174.5 0.1 3.1e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP17393.1 - 1.7e-34 119.9 9.2 2.7e-30 106.2 4.5 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Tmpp129 PF10272.9 KFP17393.1 - 0.32 10.2 2.0 0.61 9.3 2.0 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor CcmD PF04995.14 KFP17393.1 - 1.4 9.1 3.5 9.3 6.4 0.8 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) MPC PF03650.13 KFP17394.1 - 1.5e-37 128.1 0.8 1.6e-37 128.0 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers V-set PF07686.17 KFP17395.1 - 1.3e-21 76.8 0.0 1.9e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP17395.1 - 1.5e-07 31.5 0.0 6.4e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP17395.1 - 1.4e-05 25.5 0.6 7.8e-05 23.2 0.1 2.4 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP17395.1 - 8.7e-05 22.5 0.1 0.00036 20.5 0.1 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Myelin-PO_C PF10570.9 KFP17395.1 - 0.038 14.4 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region Ig_2 PF13895.6 KFP17395.1 - 0.075 13.4 0.1 0.8 10.1 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain CAP-ZIP_m PF15255.6 KFP17396.1 - 1.6e-21 77.1 1.1 1.6e-21 77.1 1.1 2.3 3 0 0 3 3 3 1 WASH complex subunit CAP-Z interacting, central region TCR_zetazeta PF11628.8 KFP17397.1 - 2.2e-18 65.6 0.3 3.2e-18 65.1 0.3 1.2 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain ITAM PF02189.15 KFP17397.1 - 6.3e-08 32.6 1.0 0.0036 17.7 0.4 2.5 2 0 0 2 2 2 2 Immunoreceptor tyrosine-based activation motif Pou PF00157.17 KFP17398.1 - 2.9e-38 129.7 0.2 7e-38 128.5 0.2 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP17398.1 - 1.4e-17 63.2 2.7 3.7e-17 61.9 2.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP17398.1 - 0.065 13.2 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain HTH_31 PF13560.6 KFP17398.1 - 0.089 13.2 1.2 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain DSPc PF00782.20 KFP17399.1 - 2.1e-26 92.3 0.0 6e-26 90.8 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ig PF00047.25 KFP17400.1 - 3.1e-14 52.9 2.8 1.1e-06 28.7 1.5 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP17400.1 - 9.5e-13 48.3 2.3 4.9e-08 33.1 0.0 3.1 2 1 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP17400.1 - 1.2e-12 48.3 3.8 2.1e-08 34.6 1.2 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP17400.1 - 1.4e-12 47.5 0.3 2.2e-07 30.8 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP17400.1 - 3.3e-12 46.6 2.7 2.9e-08 33.9 1.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 KFP17400.1 - 2.1e-06 28.0 0.1 0.0017 18.7 0.1 2.3 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP17400.1 - 1.5e-05 24.9 0.0 0.095 12.8 0.0 2.2 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP17400.1 - 4.9e-05 22.8 4.7 0.052 13.1 0.0 2.8 3 0 0 3 3 2 2 Immunoglobulin domain Ig_4 PF16680.5 KFP17400.1 - 6.7e-05 23.1 0.1 0.024 14.9 0.1 2.3 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Adeno_E3_CR1 PF02440.15 KFP17400.1 - 0.00053 19.7 0.1 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Adenovirus E3 region protein CR1 C2-set_2 PF08205.12 KFP17400.1 - 0.0012 18.9 0.6 0.0022 18.0 0.3 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.16 KFP17400.1 - 0.003 16.4 2.3 4.4 5.9 1.6 2.9 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 KFP17400.1 - 0.044 14.0 0.0 4.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Orthoreo_P10 PF07204.11 KFP17400.1 - 0.056 13.4 1.4 0.51 10.3 0.9 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 LSR PF05624.14 KFP17401.1 - 1.5e-24 85.7 33.5 2.3e-24 85.1 33.5 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.17 KFP17401.1 - 6.2e-06 26.4 0.1 0.0041 17.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain zf-H2C2_2 PF13465.6 KFP17402.1 - 2.9e-55 182.3 47.0 5.2e-09 36.1 1.1 9.0 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP17402.1 - 1.1e-48 161.0 59.3 9.9e-08 32.0 0.6 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17402.1 - 4.7e-32 107.9 55.7 0.00025 21.6 2.7 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KFP17402.1 - 8.9e-13 48.1 29.1 0.00046 20.2 4.2 6.2 5 2 1 6 6 6 5 Zinc ribbon domain zf_UBZ PF18439.1 KFP17402.1 - 3e-12 45.9 31.6 0.041 13.5 0.1 8.1 8 0 0 8 8 8 4 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KFP17402.1 - 5.9e-12 45.5 21.2 0.1 12.9 0.3 7.8 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP17402.1 - 8.9e-10 38.3 54.8 0.16 12.0 0.5 9.1 8 2 0 8 8 8 5 C2H2-type zinc finger DZR PF12773.7 KFP17402.1 - 9.8e-08 31.9 28.4 1.8e+04 -5.7 28.4 4.9 1 1 0 1 1 0 0 Double zinc ribbon XPA_N PF01286.18 KFP17402.1 - 1.3e-07 31.5 29.6 0.23 11.5 0.3 8.0 8 0 0 8 8 8 2 XPA protein N-terminal zinc_ribbon_15 PF17032.5 KFP17402.1 - 2.3e-07 31.4 20.0 0.085 13.6 0.3 4.4 1 1 5 6 6 6 6 zinc-ribbon family C1_1 PF00130.22 KFP17402.1 - 5.7e-06 26.1 26.4 0.071 13.0 0.9 6.5 1 1 6 7 7 7 4 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 KFP17402.1 - 7.5e-05 22.6 20.8 0.61 10.1 2.1 6.1 2 2 4 6 6 6 3 Adenylate kinase, active site lid FYDLN_acid PF09538.10 KFP17402.1 - 9.3e-05 23.1 13.8 4.4 8.0 0.1 6.6 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.13 KFP17402.1 - 0.00013 21.6 30.8 1.1 9.0 0.2 8.0 8 0 0 8 8 8 1 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.6 KFP17402.1 - 0.00032 20.7 24.1 1.1 9.3 0.2 7.4 2 2 5 7 7 7 1 CpXC protein YhfH PF14149.6 KFP17402.1 - 0.0013 18.6 30.1 3.8 7.6 0.1 7.9 8 0 0 8 8 8 1 YhfH-like protein zf-LYAR PF08790.11 KFP17402.1 - 0.0014 18.5 32.0 0.85 9.6 0.1 8.1 8 0 0 8 8 8 1 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 KFP17402.1 - 0.0014 18.5 33.5 0.026 14.4 4.0 6.5 5 2 1 6 6 6 3 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KFP17402.1 - 0.0033 17.2 2.9 0.041 13.6 0.2 8.0 8 0 0 8 8 8 3 zinc-finger C2H2-type zf-trcl PF13451.6 KFP17402.1 - 0.0067 16.3 26.1 5.3 7.0 0.1 7.6 8 0 0 8 8 8 0 Probable zinc-ribbon domain HypA PF01155.19 KFP17402.1 - 0.01 15.9 20.5 3.5 7.7 0.7 4.5 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 KFP17402.1 - 0.016 15.5 25.9 0.65 10.3 1.1 5.5 1 1 6 7 7 7 0 TFIIH C1-like domain zf-Di19 PF05605.12 KFP17402.1 - 0.016 15.5 27.6 0.024 14.9 1.8 5.2 1 1 5 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding DUF3268 PF11672.8 KFP17402.1 - 0.024 15.0 19.0 1.5 9.2 0.7 4.5 1 1 6 7 7 7 0 zinc-finger-containing domain LIM PF00412.22 KFP17402.1 - 0.026 14.8 28.0 1.5 9.1 0.3 5.9 1 1 6 7 7 7 0 LIM domain OSTMP1 PF09777.9 KFP17402.1 - 0.071 12.5 5.3 0.072 12.5 3.9 1.7 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-AN1 PF01428.16 KFP17402.1 - 0.082 13.1 44.0 2 8.7 4.4 8.0 5 2 3 8 8 8 0 AN1-like Zinc finger zf-C2HE PF16278.5 KFP17402.1 - 0.13 12.7 35.9 0.74 10.3 0.9 7.6 1 1 7 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zinc-ribbons_6 PF07191.12 KFP17402.1 - 0.22 11.6 27.0 2.2e+02 1.9 8.7 5.9 1 1 1 2 2 1 0 zinc-ribbons DrsE PF02635.15 KFP17402.1 - 0.23 11.8 0.4 0.79 10.1 0.0 2.1 2 0 0 2 2 1 0 DsrE/DsrF-like family zf-met PF12874.7 KFP17402.1 - 0.3 11.5 46.3 0.12 12.9 1.8 7.6 8 0 0 8 8 7 0 Zinc-finger of C2H2 type HTH_18 PF12833.7 KFP17402.1 - 0.34 11.2 2.4 2.4e+02 2.1 0.0 4.7 4 2 1 6 6 5 0 Helix-turn-helix domain TFIIS_C PF01096.18 KFP17402.1 - 0.35 10.8 34.0 7.7 6.5 0.2 7.6 6 2 1 7 7 7 0 Transcription factor S-II (TFIIS) Yippee-Mis18 PF03226.14 KFP17402.1 - 0.41 10.9 21.8 3 8.1 1.2 5.7 2 2 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-C2H2_12 PF18112.1 KFP17402.1 - 0.54 10.8 0.1 0.54 10.8 0.1 5.1 7 0 0 7 7 3 0 Autophagy receptor zinc finger-C2H2 domain PknG_rubred PF16919.5 KFP17402.1 - 0.81 9.9 30.2 0.18 12.0 3.2 5.0 1 1 3 5 5 5 0 Protein kinase G rubredoxin domain Rpr2 PF04032.16 KFP17402.1 - 0.81 10.0 22.2 1.9e+03 -0.8 20.9 4.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_recom PF13408.6 KFP17402.1 - 1.1 9.9 37.4 6 7.5 1.0 6.8 2 1 4 6 6 6 0 Recombinase zinc beta ribbon domain zinc_ribbon_9 PF14369.6 KFP17402.1 - 1.4 9.3 29.5 12 6.2 0.4 7.7 7 1 1 8 8 8 0 zinc-ribbon zf-HIT PF04438.16 KFP17402.1 - 2.2 8.3 37.1 2.7 7.9 0.4 7.5 8 0 0 8 8 8 0 HIT zinc finger Chordopox_RPO7 PF05864.12 KFP17402.1 - 2.3 8.5 16.2 47 4.3 0.1 6.5 7 1 1 8 8 7 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) BolA PF01722.18 KFP17402.1 - 3 8.2 8.4 66 3.9 0.3 3.8 2 2 1 3 3 3 0 BolA-like protein Zn_Tnp_IS1595 PF12760.7 KFP17402.1 - 4 7.5 37.1 3.9 7.5 6.5 5.9 4 2 0 5 5 5 0 Transposase zinc-ribbon domain DUF2072 PF09845.9 KFP17402.1 - 6 7.1 28.4 20 5.5 4.3 6.7 7 1 0 7 7 6 0 Zn-ribbon containing protein COX5B PF01215.19 KFP17402.1 - 6.9 6.4 13.3 3.3 7.4 0.6 4.1 1 1 3 5 5 5 0 Cytochrome c oxidase subunit Vb DUF2256 PF10013.9 KFP17402.1 - 7.1 6.8 22.1 27 5.0 0.1 7.1 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) Ig_3 PF13927.6 KFP17403.1 - 6.8e-05 23.4 0.4 0.45 11.2 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP17403.1 - 0.00055 20.0 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP17403.1 - 0.0065 16.8 0.3 0.081 13.3 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP17403.1 - 0.014 15.5 1.0 9.9 6.4 0.2 3.2 2 1 0 2 2 2 0 Immunoglobulin domain V-set PF07686.17 KFP17403.1 - 0.065 13.4 0.1 1.6 9.0 0.0 2.8 2 1 0 2 2 2 0 Immunoglobulin V-set domain Orthoreo_P10 PF07204.11 KFP17403.1 - 0.14 12.1 2.8 0.14 12.1 1.1 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Rubis-subs-bind PF09273.11 KFP17404.1 - 3.4e-29 102.1 0.1 5.7e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KFP17404.1 - 6.4e-06 26.7 2.1 1e-05 26.0 0.0 2.2 2 1 0 2 2 2 1 SET domain zf-C2H2 PF00096.26 KFP17405.1 - 4.9e-26 89.7 53.8 5.3e-06 26.6 2.8 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17405.1 - 3.2e-16 58.6 50.4 0.002 18.8 0.9 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP17405.1 - 8.6e-16 57.6 44.1 2.9e-07 30.6 1.3 7.7 7 0 0 7 7 7 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP17405.1 - 5.7e-05 22.8 34.4 9.2e-05 22.1 3.9 4.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 KFP17405.1 - 0.00067 20.0 15.6 0.013 15.8 1.2 2.7 2 1 0 2 2 2 2 zinc-finger-containing domain zf-C2H2_7 PF15269.6 KFP17405.1 - 0.0097 16.0 13.0 0.36 10.9 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger FYVE PF01363.21 KFP17405.1 - 0.012 15.7 24.9 0.2 11.8 0.5 5.3 5 0 0 5 5 5 0 FYVE zinc finger GAGA PF09237.11 KFP17405.1 - 0.074 12.9 7.9 1.7 8.5 0.6 3.0 2 1 0 2 2 2 0 GAGA factor Actin_micro PF17003.5 KFP17405.1 - 0.2 10.8 8.4 2.4 7.3 0.4 3.7 3 1 1 4 4 4 0 Putative actin-like family zf-FCS PF06467.14 KFP17405.1 - 1.4 8.9 13.1 3.1 7.8 0.1 4.1 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.8 KFP17405.1 - 2.8 8.3 44.6 0.95 9.8 1.9 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 KFP17405.1 - 9 6.5 14.6 14 5.9 0.5 4.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Pkinase PF00069.25 KFP17407.1 - 2.9e-14 53.1 0.0 5.8e-14 52.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17407.1 - 1.9e-08 33.9 0.2 1e-07 31.5 0.1 2.4 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP17407.1 - 0.00026 19.9 1.4 0.008 15.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP17407.1 - 0.029 14.3 0.1 0.15 12.0 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family EcKinase PF02958.20 KFP17407.1 - 0.045 13.1 0.1 0.089 12.1 0.1 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Kinase-like PF14531.6 KFP17407.1 - 0.061 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAP_central PF04928.17 KFP17408.1 - 2.9e-116 386.8 0.0 2.9e-116 386.8 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFP17408.1 - 1.6e-25 89.7 5.2 5.8e-19 68.4 0.0 3.0 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFP17408.1 - 6.8e-14 51.9 0.1 2e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF727 PF05303.12 KFP17409.1 - 4.9e-32 110.1 0.0 6e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) 7tm_1 PF00001.21 KFP17411.1 - 7e-49 166.5 27.7 9.4e-49 166.1 27.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glutaredoxin PF00462.24 KFP17413.1 - 1.9e-05 24.8 0.2 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF2639 PF11121.8 KFP17413.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) KASH PF10541.9 KFP17415.1 - 3.9e-25 87.9 8.1 8.5e-25 86.8 8.1 1.6 1 0 0 1 1 1 1 Nuclear envelope localisation domain Spectrin PF00435.21 KFP17415.1 - 2.5e-14 53.7 79.2 4.1e-06 27.2 3.8 8.6 5 1 4 9 9 9 6 Spectrin repeat SnoaL PF07366.12 KFP17415.1 - 0.061 13.1 0.2 15 5.4 0.1 4.0 4 0 0 4 4 4 0 SnoaL-like polyketide cyclase IL4 PF00727.18 KFP17415.1 - 0.083 13.1 2.7 4.5 7.5 0.2 3.4 2 0 0 2 2 2 0 Interleukin 4 CTD_bind PF04818.13 KFP17415.1 - 0.093 13.6 0.9 9.6 7.1 0.0 3.9 3 0 0 3 3 3 0 RNA polymerase II-binding domain. DUF5064 PF16703.5 KFP17415.1 - 0.1 13.1 0.0 0.37 11.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5064) DUF2120 PF09893.9 KFP17415.1 - 2.1 8.5 10.8 1.3 9.1 0.9 3.6 2 2 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2120) DASH_Dad1 PF08649.10 KFP17415.1 - 7 6.9 7.2 11 6.3 0.1 4.4 4 0 0 4 4 4 0 DASH complex subunit Dad1 RVT_1 PF00078.27 KFP17417.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CH PF00307.31 KFP17418.1 - 1.4e-38 131.5 0.5 1.2e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP17418.1 - 8.7e-08 31.9 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KFP17418.1 - 0.024 14.8 0.1 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein RcsD_ABL PF16359.5 KFP17418.1 - 0.064 13.4 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 RcsD-ABL domain Ribonuclease_3 PF00636.26 KFP17421.1 - 7.7e-70 232.2 0.7 7.3e-44 148.7 0.0 3.3 3 1 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.22 KFP17421.1 - 8.8e-40 135.7 0.7 5.3e-39 133.2 0.2 2.5 2 0 0 2 2 2 1 PAZ domain Ribonucleas_3_3 PF14622.6 KFP17421.1 - 7e-25 87.6 0.0 1.5e-16 60.7 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KFP17421.1 - 1.8e-24 85.7 0.0 7.1e-24 83.8 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KFP17421.1 - 4.2e-18 65.7 0.1 1.8e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP17421.1 - 8.2e-14 52.0 0.0 2.4e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP17421.1 - 1.6e-13 50.8 0.3 3.8e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFP17421.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) dsrm PF00035.26 KFP17421.1 - 0.081 13.6 0.0 0.36 11.6 0.0 2.2 1 0 0 1 1 1 0 Double-stranded RNA binding motif Flavi_DEAD PF07652.14 KFP17421.1 - 0.15 12.1 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain Homeodomain PF00046.29 KFP17422.1 - 2.9e-23 81.5 5.6 4.9e-23 80.7 5.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP17422.1 - 0.00085 19.2 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF3437 PF11919.8 KFP17422.1 - 0.21 11.5 2.8 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Serpin PF00079.20 KFP17423.1 - 3.7e-115 385.2 0.1 4.1e-115 385.0 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFP17425.1 - 3.4e-120 401.8 3.7 3.9e-120 401.6 3.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFP17426.1 - 5.5e-117 391.2 5.4 6.2e-117 391.0 5.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2247 PF10004.9 KFP17426.1 - 0.048 13.4 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) HEAT PF02985.22 KFP17427.1 - 5.7e-12 44.8 3.8 0.51 10.7 0.1 7.5 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KFP17427.1 - 2.6e-05 24.7 3.4 1.1 9.9 0.1 4.6 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFP17427.1 - 0.00012 22.4 0.4 0.0033 17.8 0.0 3.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KFP17427.1 - 0.038 14.5 5.8 2.8 8.5 0.0 4.8 5 1 0 5 5 5 0 HEAT-like repeat Caa3_CtaG PF09678.10 KFP17427.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Arm PF00514.23 KFP17427.1 - 0.93 9.6 3.6 19 5.5 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Helicase_C PF00271.31 KFP17428.1 - 3.8e-29 101.3 0.2 6e-26 91.0 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP17428.1 - 9e-28 97.2 1.7 1.9e-25 89.7 0.1 3.0 2 1 1 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP17428.1 - 0.037 14.3 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain ExbD PF02472.16 KFP17428.1 - 5 7.3 9.4 1.3 9.1 0.2 3.5 4 0 0 4 4 4 0 Biopolymer transport protein ExbD/TolR Ig_mannosidase PF17753.1 KFP17429.1 - 4e-21 74.6 0.5 1.4e-20 72.8 0.5 2.0 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KFP17429.1 - 1.8e-12 47.7 0.0 4.7e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 KFP17429.1 - 6.2e-08 32.1 0.3 3.5e-07 29.6 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFP17429.1 - 1.9e-05 24.6 0.3 5.7e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain VP40 PF07447.12 KFP17429.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Matrix protein VP40 zf-CDGSH PF09360.10 KFP17430.1 - 4.4e-10 39.6 0.2 7.4e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 KFP17430.1 - 3.8e-09 36.4 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Na_H_Exchanger PF00999.21 KFP17431.1 - 2.8e-27 95.5 32.8 2.8e-27 95.5 32.8 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family RAMP4 PF06624.12 KFP17431.1 - 9.5 6.4 12.2 13 6.0 1.0 2.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 adh_short_C2 PF13561.6 KFP17432.1 - 2.2e-58 197.6 0.0 2.5e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP17432.1 - 3.1e-42 144.2 0.1 4e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFP17432.1 - 1.2e-05 25.3 0.1 1.8e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 KFP17432.1 - 0.0078 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2325 PF10087.9 KFP17432.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Sacchrp_dh_NADP PF03435.18 KFP17432.1 - 0.032 14.5 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 KFP17432.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FtsJ PF01728.19 KFP17432.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase NAD_binding_10 PF13460.6 KFP17432.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 KFP17432.1 - 0.12 11.7 0.2 0.18 11.1 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Radial_spoke PF04712.12 KFP17433.1 - 2.3e-202 673.3 6.5 2.3e-202 673.3 6.5 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein 7tm_1 PF00001.21 KFP17434.1 - 7.5e-59 199.2 19.1 9.8e-59 198.8 19.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17434.1 - 1.9e-10 40.6 19.3 2.7e-10 40.1 19.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP17434.1 - 2.6e-05 24.1 18.4 0.00021 21.1 18.4 2.1 1 1 0 1 1 1 1 Olfactory receptor zf_C2H2_ZHX PF18387.1 KFP17434.1 - 0.16 11.6 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain START PF01852.19 KFP17435.1 - 3.2e-47 160.6 0.0 3.9e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 KFP17435.1 - 0.0019 18.4 0.0 0.0088 16.3 0.0 2.1 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFP17435.1 - 0.12 12.6 0.0 0.42 10.9 0.0 2.1 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport SPRY PF00622.28 KFP17436.1 - 9e-12 45.2 0.2 0.00012 22.1 0.0 2.4 2 0 0 2 2 2 2 SPRY domain eIF_4EBP PF05456.11 KFP17437.1 - 4e-24 84.8 0.0 4.4e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Nucleoplasmin PF03066.15 KFP17438.1 - 7e-10 39.3 0.1 1e-09 38.8 0.1 1.3 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain RBD-FIP PF09457.10 KFP17439.1 - 6.4e-16 58.0 2.6 6.4e-16 58.0 2.6 1.7 2 0 0 2 2 2 1 FIP domain TFIIB PF00382.19 KFP17440.1 - 0.00015 21.7 0.0 0.69 10.0 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIIB repeat RB_B PF01857.20 KFP17440.1 - 0.019 15.0 0.2 0.05 13.6 0.1 1.6 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain Ala_racemase_N PF01168.20 KFP17441.1 - 8.6e-15 55.0 0.0 1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Band_7 PF01145.25 KFP17442.1 - 1.4e-09 38.2 0.7 1.4e-09 38.2 0.7 1.8 1 1 2 3 3 3 1 SPFH domain / Band 7 family DUF4346 PF14251.6 KFP17442.1 - 0.03 14.4 1.4 0.065 13.3 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) RapA_C PF12137.8 KFP17442.1 - 0.059 12.4 5.6 0.11 11.5 5.6 1.5 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal PsbL PF02419.17 KFP17443.1 - 1.1 9.4 3.7 1.9 8.5 3.7 1.5 1 0 0 1 1 1 0 PsbL protein PHP PF02811.19 KFP17444.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 PHP domain Ribosomal_L28e PF01778.17 KFP17445.1 - 1.8e-35 122.2 0.2 1.8e-35 122.2 0.2 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KFP17445.1 - 1.1e-30 106.2 14.2 1.1e-30 106.2 14.2 2.7 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 KFP17445.1 - 0.001 18.5 16.7 0.0013 18.1 16.7 1.1 1 0 0 1 1 1 1 BUD22 SAPS PF04499.15 KFP17445.1 - 0.26 10.0 7.0 0.3 9.8 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2201_N PF13203.6 KFP17445.1 - 0.76 9.3 5.5 1.1 8.8 5.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain MFS_1 PF07690.16 KFP17446.1 - 6.4e-40 137.1 44.8 5.9e-32 110.9 35.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP17446.1 - 2.5e-07 29.9 5.2 2.5e-07 29.9 5.2 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 KFP17446.1 - 0.66 8.7 17.3 0.34 9.6 3.2 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter CPP1-like PF11833.8 KFP17446.1 - 2.3 7.8 4.1 5.3 6.6 3.6 1.9 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ATP-synt_ab PF00006.25 KFP17447.1 - 3.4e-67 226.2 0.0 4.8e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFP17447.1 - 4.2e-13 49.6 0.4 1e-12 48.4 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF2481 PF10654.9 KFP17447.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Ank PF00023.30 KFP17449.1 - 6.4e-32 108.6 15.0 7.8e-06 26.1 0.4 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.7 KFP17449.1 - 3.7e-28 97.9 6.5 3.7e-10 40.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP17449.1 - 1.6e-27 95.5 5.3 1.3e-05 25.6 0.1 7.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP17449.1 - 1.1e-26 92.5 7.5 7.2e-09 35.7 0.2 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP17449.1 - 9e-26 87.1 6.8 0.00039 20.6 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat SOCS_box PF07525.16 KFP17449.1 - 6.4e-07 29.6 6.6 6.4e-07 29.6 6.6 2.2 2 0 0 2 2 2 1 SOCS box ABC_tran PF00005.27 KFP17450.1 - 3.2e-47 160.5 0.0 1.4e-24 87.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KFP17450.1 - 9e-22 76.9 3.7 9e-22 76.9 3.7 2.6 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KFP17450.1 - 8.4e-16 58.6 2.3 0.00019 21.3 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP17450.1 - 6.5e-07 29.0 0.4 0.37 10.2 0.0 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFP17450.1 - 5.4e-06 26.0 0.2 0.0045 16.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP17450.1 - 6.5e-05 22.9 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 KFP17450.1 - 6.5e-05 22.8 2.8 0.028 14.1 0.1 3.4 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFP17450.1 - 9.3e-05 22.5 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KFP17450.1 - 0.00012 22.2 0.1 0.12 12.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFP17450.1 - 0.00015 22.2 0.0 0.32 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KFP17450.1 - 0.0004 20.2 0.2 0.7 9.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain Rop PF01815.16 KFP17450.1 - 0.0014 18.5 1.9 0.16 11.9 0.1 2.8 2 0 0 2 2 2 1 Rop protein AAA_22 PF13401.6 KFP17450.1 - 0.0015 18.8 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFP17450.1 - 0.0047 16.9 0.8 1.1 9.2 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_14 PF13173.6 KFP17450.1 - 0.0057 16.7 0.0 0.97 9.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KFP17450.1 - 0.0059 16.9 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFP17450.1 - 0.01 16.4 10.8 0.015 15.8 0.1 3.6 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 KFP17450.1 - 0.019 15.4 0.1 1.8 9.0 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP17450.1 - 0.022 15.3 1.0 0.4 11.2 0.0 3.0 3 1 0 3 3 2 0 AAA domain AAA_27 PF13514.6 KFP17450.1 - 0.023 14.3 0.6 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KFP17450.1 - 0.034 13.9 0.0 0.33 10.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KFP17450.1 - 0.044 13.8 0.2 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFP17450.1 - 0.051 14.0 0.0 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KFP17450.1 - 0.053 12.7 0.0 6.4 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KFP17450.1 - 0.085 12.9 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KFP17450.1 - 0.096 12.4 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 KFP17450.1 - 0.14 11.2 4.7 2.9 6.8 0.0 3.0 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KFP17450.1 - 0.14 11.7 0.1 2.5 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KFP17450.1 - 1.7 8.7 3.6 1.6 8.8 0.0 2.7 3 1 1 4 4 3 0 Helicase HerA, central domain DUF3584 PF12128.8 KFP17450.1 - 1.8 6.0 7.2 0.43 8.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 KFP17450.1 - 5.4 7.3 7.3 2.3 8.4 2.5 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CHGN PF05679.16 KFP17451.1 - 2.9e-159 531.2 0.0 3.8e-159 530.8 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFP17451.1 - 1.1e-10 41.4 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Fringe-like SWIB PF02201.18 KFP17452.1 - 1.7e-24 85.5 0.2 4.6e-24 84.1 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain LRR_8 PF13855.6 KFP17453.1 - 1.5e-26 91.9 31.8 5.7e-09 35.6 1.6 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP17453.1 - 1.3e-17 63.5 22.1 9.1e-08 32.3 3.1 5.0 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP17453.1 - 9e-05 22.5 13.8 4.9 8.1 0.4 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP17453.1 - 0.0094 15.9 16.8 4 7.7 0.3 5.5 7 0 0 7 7 7 4 Leucine Rich repeat ER PF01133.17 KFP17453.1 - 0.13 12.3 0.4 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Enhancer of rudimentary UQ_con PF00179.26 KFP17454.1 - 1.7e-10 40.7 0.0 6e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP17454.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic E2 family B IL13 PF03487.13 KFP17454.1 - 0.03 14.1 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin-13 NA37 PF04245.13 KFP17454.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Josephin PF02099.17 KFP17454.1 - 0.11 12.5 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Josephin KIAA1430 PF13879.6 KFP17454.1 - 0.34 11.7 1.9 1.5 9.7 0.1 2.6 2 1 1 3 3 3 0 KIAA1430 homologue Ric8 PF10165.9 KFP17457.1 - 4.5e-129 431.5 1.2 4.5e-129 431.5 1.2 1.9 2 1 0 2 2 2 1 Guanine nucleotide exchange factor synembryn SIR2 PF02146.17 KFP17458.1 - 8.1e-56 188.7 0.0 1e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Glyco_hydro_65m PF03632.15 KFP17459.1 - 2e-58 198.1 0.3 1.4e-51 175.6 2.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain CHGN PF05679.16 KFP17460.1 - 1.9e-24 86.4 0.0 6.4e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP17460.1 - 1.9e-07 30.7 2.0 3.5e-07 29.8 2.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PA14 PF07691.12 KFP17460.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Arm PF00514.23 KFP17461.1 - 4e-20 71.1 1.2 3.4e-06 26.9 0.0 5.8 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP17461.1 - 0.0015 19.0 0.5 0.15 12.6 0.0 3.8 4 0 0 4 4 4 1 HEAT-like repeat Atx10homo_assoc PF09759.9 KFP17461.1 - 0.0019 18.1 0.9 0.14 12.2 0.1 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 KFP17461.1 - 0.055 13.9 0.0 0.29 11.6 0.0 2.2 1 1 0 1 1 1 0 HEAT repeats V-ATPase_H_C PF11698.8 KFP17461.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 V-ATPase subunit H Adaptin_N PF01602.20 KFP17461.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region Ig_3 PF13927.6 KFP17462.1 - 7.4e-07 29.7 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP17462.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain BiPBP_C PF06832.12 KFP17462.1 - 0.031 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family RVT_1 PF00078.27 KFP17463.1 - 0.00073 19.1 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM252 PF15664.5 KFP17464.1 - 5e-32 110.5 0.1 5e-32 110.5 0.1 1.3 2 0 0 2 2 2 1 Transmembrane protein 252 family PGM_PMM_III PF02880.16 KFP17465.1 - 7.8e-28 97.0 0.0 1.4e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 KFP17465.1 - 7.8e-15 54.8 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFP17465.1 - 8.7e-13 48.8 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II cobW PF02492.19 KFP17466.1 - 5.4e-46 156.4 0.1 7.4e-46 155.9 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFP17466.1 - 1.8e-19 69.5 0.0 3e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KFP17466.1 - 5.9e-05 22.7 0.3 0.0015 18.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP17466.1 - 0.00065 19.7 0.2 0.6 10.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Phenyl_P_gamma PF09662.10 KFP17466.1 - 0.08 13.1 0.1 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) GRIP PF01465.20 KFP17467.1 - 1.3e-17 63.4 0.2 2.4e-16 59.3 0.0 2.7 2 0 0 2 2 2 1 GRIP domain SPA PF08616.10 KFP17468.1 - 1.8e-14 53.7 0.0 4.8e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 KFP17468.1 - 1.3e-06 28.5 8.5 1.4e-06 28.4 4.5 2.5 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 KFP17468.1 - 0.0016 17.2 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.6 KFP17468.1 - 0.24 12.0 1.4 0.56 10.8 0.1 2.2 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein DUF5585 PF17823.1 KFP17469.1 - 1.8e-19 70.0 103.4 2.2e-16 59.9 103.4 3.2 1 1 0 1 1 1 1 Family of unknown function (DUF5585) 7tm_4 PF13853.6 KFP17470.1 - 1e-25 91.1 4.7 1.1e-25 91.0 4.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP17470.1 - 0.00013 21.4 11.7 0.00021 20.7 11.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WBP-1 PF11669.8 KFP17470.1 - 0.037 14.7 0.3 0.051 14.2 0.3 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 OSTMP1 PF09777.9 KFP17470.1 - 0.06 12.7 1.1 0.086 12.2 1.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3989 PF13150.6 KFP17470.1 - 0.86 9.4 3.0 0.84 9.4 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3989) FCH PF00611.23 KFP17471.1 - 3.3e-20 72.1 0.8 2.5e-19 69.3 0.0 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFP17471.1 - 1.3e-12 47.1 0.1 2.8e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP17471.1 - 2.9e-11 43.1 0.0 6.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP17471.1 - 1.1e-06 28.2 0.1 2.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP17471.1 - 8.3e-05 22.8 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.6 KFP17471.1 - 0.0018 18.5 0.9 0.0053 17.0 0.9 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.16 KFP17471.1 - 0.0058 16.7 0.4 0.0058 16.7 0.4 3.4 3 0 0 3 3 3 1 Hr1 repeat COG5 PF10392.9 KFP17471.1 - 0.068 13.3 0.2 0.068 13.3 0.2 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4140 PF13600.6 KFP17471.1 - 0.084 13.3 6.8 0.59 10.6 0.2 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DEDD_Tnp_IS110 PF01548.17 KFP17471.1 - 0.33 10.8 5.7 0.062 13.2 0.9 2.2 2 0 0 2 2 2 0 Transposase Exonuc_VII_L PF02601.15 KFP17471.1 - 0.67 9.5 12.0 0.33 10.5 5.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Uds1 PF15456.6 KFP17471.1 - 6.2 7.0 15.7 0.13 12.4 1.3 3.0 2 1 0 2 2 2 0 Up-regulated During Septation CBFD_NFYB_HMF PF00808.23 KFP17472.1 - 2.7e-23 82.0 2.5 4.1e-23 81.4 0.8 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP17472.1 - 5.1e-05 23.6 0.1 0.0001 22.6 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 KFP17472.1 - 0.00051 20.2 0.5 0.0012 19.0 0.1 1.6 2 0 0 2 2 2 1 CENP-W protein SLED PF12140.8 KFP17472.1 - 0.015 15.8 0.1 0.23 12.0 0.1 2.1 2 0 0 2 2 2 0 SLED domain AAA_32 PF13654.6 KFP17472.1 - 0.019 13.7 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RexA PF15969.5 KFP17472.1 - 0.03 13.9 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component Bromo_TP PF07524.13 KFP17472.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated adh_short PF00106.25 KFP17473.1 - 9.9e-40 136.1 0.0 1.4e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP17473.1 - 9.3e-26 90.8 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP17473.1 - 7.7e-10 39.0 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KFP17473.1 - 0.00038 20.2 0.0 0.0073 16.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 KFP17473.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KFP17473.1 - 0.084 12.2 0.0 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) EMP24_GP25L PF01105.24 KFP17474.1 - 1.4e-36 126.1 0.4 1.6e-36 125.9 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Mtf2_C PF14061.6 KFP17475.1 - 3.3e-27 94.4 0.1 6.3e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD PF00628.29 KFP17475.1 - 8.5e-17 60.8 27.7 1.9e-12 46.9 8.0 2.4 2 0 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 KFP17475.1 - 3.3e-13 49.0 0.0 7.5e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Prok-RING_1 PF14446.6 KFP17475.1 - 0.00014 21.7 3.3 0.00014 21.7 3.3 2.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 1 DUF4537 PF15057.6 KFP17475.1 - 0.0021 18.1 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 KFP17475.1 - 0.0028 17.7 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF3682 PF12446.8 KFP17475.1 - 0.0076 16.7 2.8 0.015 15.8 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) C1_1 PF00130.22 KFP17475.1 - 0.016 15.0 1.1 0.016 15.0 1.1 3.0 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3573 PF12097.8 KFP17475.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Chromo PF00385.24 KFP17475.1 - 0.12 12.3 0.3 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain FYVE_2 PF02318.16 KFP17475.1 - 1.4 9.2 18.7 0.095 12.9 2.1 3.2 3 0 0 3 3 3 0 FYVE-type zinc finger PHD_3 PF13922.6 KFP17475.1 - 3.8 8.0 9.5 2.1 8.8 0.3 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PIP49_C PF12260.8 KFP17476.1 - 2.2e-66 223.1 0.1 4e-66 222.3 0.1 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFP17476.1 - 4.5e-58 195.6 0.2 4.5e-58 195.6 0.2 2.2 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 Ribosomal_L5e PF17144.4 KFP17477.1 - 2e-94 314.1 1.0 2e-94 314.1 1.0 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFP17477.1 - 4.3e-39 133.4 9.5 4.3e-39 133.4 9.5 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF1476 PF07345.11 KFP17477.1 - 0.0096 16.3 0.2 0.022 15.1 0.2 1.6 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta RabGAP-TBC PF00566.18 KFP17478.1 - 5.8e-54 183.0 2.7 5.8e-54 183.0 2.7 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1129 PF06570.11 KFP17478.1 - 0.087 12.3 0.2 0.087 12.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PARP_reg PF02877.14 KFP17478.1 - 0.13 12.4 8.0 0.14 12.2 0.7 2.9 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain DUF1707 PF08044.11 KFP17478.1 - 0.29 11.3 2.9 0.99 9.5 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Surfac_D-trimer PF09006.11 KFP17478.1 - 0.95 9.4 7.2 10 6.1 0.2 4.1 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DUF2730 PF10805.8 KFP17478.1 - 4.9 7.3 24.8 0.58 10.3 1.9 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) zf-C2H2 PF00096.26 KFP17479.1 - 4.2e-29 99.3 48.2 8.2e-06 26.0 1.0 6.8 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP17479.1 - 3.3e-27 93.6 41.9 1.4e-06 28.5 2.0 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP17479.1 - 1.1e-22 78.8 41.6 0.00074 20.1 0.8 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP17479.1 - 3.9e-15 55.4 39.1 0.0026 17.7 2.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP17479.1 - 4.2e-15 55.6 15.4 0.0081 16.4 0.0 6.4 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP17479.1 - 2.7e-07 30.8 26.1 0.011 16.1 0.3 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type Ta0938 PF11494.8 KFP17479.1 - 7.2e-05 23.0 1.6 0.031 14.6 0.0 2.8 2 1 1 3 3 3 1 Ta0938 zf-BED PF02892.15 KFP17479.1 - 0.00087 19.3 29.3 0.02 14.9 0.9 5.7 4 1 1 6 6 6 2 BED zinc finger zf_UBZ PF18439.1 KFP17479.1 - 0.0017 17.9 17.3 6.7 6.4 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFP17479.1 - 0.0022 18.3 21.6 0.15 12.4 3.6 4.4 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 KFP17479.1 - 0.0084 16.1 10.2 0.47 10.6 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger domain zf-C2H2_3rep PF18868.1 KFP17479.1 - 0.011 16.4 20.2 0.68 10.6 2.1 4.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KFP17479.1 - 0.026 14.2 1.5 0.026 14.2 1.5 3.4 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_1 PF14446.6 KFP17479.1 - 0.055 13.4 15.9 9.2 6.3 0.1 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 FYVE PF01363.21 KFP17479.1 - 0.059 13.5 25.8 1.6 8.9 9.3 4.0 1 1 3 4 4 4 0 FYVE zinc finger GAGA PF09237.11 KFP17479.1 - 0.085 12.7 6.8 6.6 6.6 0.0 4.2 2 2 2 4 4 4 0 GAGA factor zinc_ribbon_15 PF17032.5 KFP17479.1 - 0.12 13.1 12.7 21 5.9 3.3 3.5 1 1 1 2 2 2 0 zinc-ribbon family BolA PF01722.18 KFP17479.1 - 0.18 12.1 7.5 0.98 9.7 0.5 3.4 2 2 0 2 2 2 0 BolA-like protein HypA PF01155.19 KFP17479.1 - 0.19 11.8 11.5 1.2 9.1 0.4 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HNH_5 PF14279.6 KFP17479.1 - 0.2 11.6 17.7 3.7 7.5 0.8 5.8 6 1 0 6 6 5 0 HNH endonuclease zf-C2H2_11 PF16622.5 KFP17479.1 - 0.2 11.4 29.8 4.9 7.0 0.2 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFP17479.1 - 0.27 11.2 25.5 1.8 8.6 1.0 6.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFP17479.1 - 0.63 10.0 13.9 1.6 8.7 0.1 5.1 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_ZIC PF18366.1 KFP17479.1 - 0.65 10.1 18.1 2.5 8.3 0.1 5.1 3 1 3 6 6 6 0 Zic proteins zinc finger domain Zn-ribbon_8 PF09723.10 KFP17479.1 - 0.82 9.8 28.4 1.2 9.3 2.9 5.7 4 3 2 6 6 5 0 Zinc ribbon domain XPA_N PF01286.18 KFP17479.1 - 1.6 8.8 23.6 8 6.6 0.1 6.7 7 0 0 7 7 7 0 XPA protein N-terminal Ribosomal_S27e PF01667.17 KFP17479.1 - 2.2 8.1 10.4 1.4 8.7 0.1 4.5 4 1 1 5 5 5 0 Ribosomal protein S27 zf-C2H2_2 PF12756.7 KFP17479.1 - 2.2 8.7 23.5 8.1 6.9 0.2 5.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 KFP17479.1 - 3.1 8.0 17.9 14 5.9 0.6 5.4 1 1 5 6 6 6 0 KIAA1045 RING finger zf-AN1 PF01428.16 KFP17479.1 - 4.4 7.5 34.0 5.3 7.3 0.7 6.8 5 2 2 7 7 7 0 AN1-like Zinc finger Arc_trans_TRASH PF08394.10 KFP17479.1 - 6 7.3 9.2 57 4.2 0.1 4.6 3 2 0 3 3 3 0 Archaeal TRASH domain ADK_lid PF05191.14 KFP17479.1 - 6.6 6.8 15.3 22 5.2 4.6 4.7 3 2 1 4 4 4 0 Adenylate kinase, active site lid RPAP2_Rtr1 PF04181.13 KFP17480.1 - 4e-24 84.7 3.2 4e-24 84.7 3.2 2.8 3 0 0 3 3 3 1 Rtr1/RPAP2 family Peptidase_M27 PF01742.17 KFP17480.1 - 0.0063 15.7 0.2 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Clostridial neurotoxin zinc protease Kinetochor_Ybp2 PF08568.10 KFP17481.1 - 1.6e-89 301.1 19.5 2.1e-89 300.7 19.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-AD PF07776.15 KFP17481.1 - 0.0046 17.2 0.1 0.018 15.2 0.1 2.1 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) Colipase-like PF15083.6 KFP17481.1 - 0.051 13.7 0.8 0.051 13.7 0.8 2.7 3 0 0 3 3 3 0 Colipase-like DUF4580 PF15162.6 KFP17482.1 - 2.3e-76 254.9 1.0 2.6e-76 254.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) DUF4596 PF15363.6 KFP17483.1 - 1.5e-28 98.7 5.9 1.3e-27 95.7 5.9 2.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4596) BACK PF07707.15 KFP17483.1 - 0.077 13.1 0.2 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch BTB PF00651.31 KFP17484.1 - 1.9e-21 76.4 0.0 1.2e-20 73.8 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain SPOB_ab PF14682.6 KFP17484.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Abhydrolase_1 PF00561.20 KFP17485.1 - 3.9e-24 85.7 0.0 6.5e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP17485.1 - 1.4e-19 71.6 0.0 1.8e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP17485.1 - 5.8e-11 42.1 0.0 3e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KFP17485.1 - 7.4e-05 21.6 0.0 0.0045 15.7 0.0 2.1 2 0 0 2 2 2 2 Ndr family PGAP1 PF07819.13 KFP17485.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KFP17485.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Bromodomain PF00439.25 KFP17486.1 - 4e-32 110.1 1.8 4.8e-19 68.2 0.4 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFP17486.1 - 1.2e-27 95.9 3.6 1.7e-27 95.4 0.2 2.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation BRD4_CDT PF17105.5 KFP17486.1 - 2.7e-23 81.3 5.0 2.7e-23 81.3 5.0 2.1 2 0 0 2 2 2 1 C-terminal domain of bromodomain protein 4 Zona_pellucida PF00100.23 KFP17487.1 - 9.7e-41 140.3 0.9 2.1e-40 139.2 0.9 1.6 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase PF00069.25 KFP17488.1 - 8.3e-48 163.0 0.0 8e-26 91.0 0.1 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17488.1 - 3.7e-17 62.5 0.0 2.1e-13 50.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KFP17488.1 - 0.0079 16.1 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP17488.1 - 0.069 12.5 0.5 13 5.0 0.0 3.1 3 0 0 3 3 3 0 Kinase-like DEAD PF00270.29 KFP17489.1 - 0.00097 18.9 0.2 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4992 PF16383.5 KFP17489.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Glutaredoxin PF00462.24 KFP17490.1 - 1.3e-19 70.2 0.0 1.4e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 KFP17490.1 - 1.7e-18 66.5 0.2 5.9e-18 64.8 0.0 2.0 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP17490.1 - 3.2e-08 34.0 0.1 5e-07 30.1 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.16 KFP17490.1 - 3.6e-05 23.5 0.0 5.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 KFP17490.1 - 0.00021 21.5 0.0 0.066 13.6 0.0 3.3 2 1 1 3 3 3 1 Thioredoxin-like Phosducin PF02114.16 KFP17490.1 - 0.00024 20.1 0.0 0.00048 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosducin OST3_OST6 PF04756.13 KFP17490.1 - 0.00042 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KFP17490.1 - 0.00049 20.1 0.1 0.0041 17.1 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 KFP17490.1 - 0.0023 17.9 0.1 0.053 13.5 0.0 2.8 2 1 2 4 4 4 1 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.10 KFP17490.1 - 0.065 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein SH3_2 PF07653.17 KFP17491.1 - 3e-13 49.2 0.0 3.2e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP17491.1 - 6.4e-13 48.1 0.0 7.8e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP17491.1 - 5.4e-12 45.4 0.0 6.2e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain Metallophos PF00149.28 KFP17492.1 - 1.8e-36 126.5 0.0 3.1e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zip PF02535.22 KFP17493.1 - 9.6e-20 71.1 9.1 3.6e-16 59.3 1.4 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter Piwi PF02171.17 KFP17494.1 - 5.4e-69 232.7 0.0 2.2e-48 165.0 0.0 2.2 1 1 1 2 2 2 2 Piwi domain EPTP PF03736.17 KFP17495.1 - 7.7e-66 217.9 8.3 1.5e-11 44.1 0.0 6.3 6 0 0 6 6 6 6 EPTP domain LRR_8 PF13855.6 KFP17495.1 - 2.6e-22 78.4 12.5 1.1e-13 50.7 6.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 KFP17495.1 - 6.1e-09 35.9 0.1 1.2e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP17495.1 - 9.2e-07 29.1 10.4 0.0012 19.1 1.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP17495.1 - 1.6e-05 24.5 0.2 2.8e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRRCT PF01463.24 KFP17495.1 - 0.00017 21.8 0.1 0.0022 18.4 0.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFP17495.1 - 0.091 13.4 9.5 7.4 7.5 0.5 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat RCDG1 PF15725.5 KFP17495.1 - 0.61 10.5 3.0 2.7 8.5 1.6 2.4 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Transglut_C PF00927.22 KFP17496.1 - 1e-37 128.5 0.4 2.7e-20 72.5 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 KFP17496.1 - 5.9e-33 113.7 0.3 1.3e-32 112.6 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 KFP17496.1 - 1.2e-15 58.0 0.1 2.4e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily MG2 PF01835.19 KFP17496.1 - 0.00064 20.1 0.1 0.0018 18.7 0.1 1.7 1 0 0 1 1 1 1 MG2 domain Poxvirus_B22R PF04395.12 KFP17496.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein DUF2393 PF09624.10 KFP17496.1 - 0.58 10.1 2.2 0.76 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) Transglut_N PF00868.20 KFP17498.1 - 1.1e-30 106.4 0.0 3.1e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP17498.1 - 2.3e-27 95.2 0.2 1.7e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP17498.1 - 1.8e-17 63.8 0.3 4.8e-17 62.4 0.3 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 KFP17499.1 - 1.4e-32 112.5 0.0 3.3e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP17499.1 - 1.9e-28 98.7 0.4 1.6e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP17499.1 - 1.6e-15 57.6 0.3 3.9e-15 56.3 0.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.20 KFP17500.1 - 1.9e-35 121.8 0.0 3.5e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.22 KFP17500.1 - 1.1e-29 102.6 0.1 3.2e-16 59.4 0.0 3.1 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP17500.1 - 2.8e-16 59.9 0.8 6e-16 58.9 0.8 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily MG2 PF01835.19 KFP17500.1 - 0.022 15.2 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 MG2 domain SUR7 PF06687.12 KFP17500.1 - 0.034 13.8 0.2 0.061 13.0 0.2 1.4 1 0 0 1 1 1 0 SUR7/PalI family GCIP PF13324.6 KFP17501.1 - 2.8e-88 295.9 2.1 3.2e-88 295.7 2.1 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DEAD PF00270.29 KFP17502.1 - 2.7e-45 154.3 0.2 2.8e-44 151.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP17502.1 - 6.5e-30 103.7 0.2 2.6e-28 98.6 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP17502.1 - 4.2e-06 26.9 0.0 4.2e-06 26.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFP17502.1 - 0.002 18.4 1.6 0.029 14.6 1.6 2.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFP17502.1 - 0.09 12.5 3.5 0.27 11.0 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family LSM PF01423.22 KFP17503.1 - 1.5e-17 63.0 0.0 2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF3361 PF11841.8 KFP17504.1 - 3.1e-56 189.6 5.2 6.9e-56 188.5 5.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFP17504.1 - 6e-40 137.2 0.3 1e-39 136.5 0.3 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFP17504.1 - 1.9e-38 132.0 0.1 8.7e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SIL1 PF16782.5 KFP17504.1 - 0.012 14.8 2.7 0.039 13.2 2.7 1.9 1 1 0 1 1 1 0 Nucleotide exchange factor SIL1 Cas_CT1975 PF09344.10 KFP17504.1 - 0.054 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 CT1975-like protein TPT PF03151.16 KFP17505.1 - 6.9e-13 48.6 6.1 1.7e-12 47.3 6.1 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP17505.1 - 3.6e-05 24.0 23.9 0.00012 22.2 6.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family SPC25 PF06703.11 KFP17505.1 - 0.088 12.6 1.6 0.14 11.9 1.6 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UAA PF08449.11 KFP17505.1 - 0.097 11.9 16.5 1.4 8.1 16.5 2.0 1 1 0 1 1 1 0 UAA transporter family DUF1129 PF06570.11 KFP17505.1 - 1.4 8.4 5.3 2.6 7.5 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Cadherin PF00028.17 KFP17506.1 - 4.7e-75 248.1 9.9 1.1e-17 64.2 0.2 5.4 5 1 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP17506.1 - 1.4e-47 161.7 0.3 2.5e-47 160.8 0.3 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP17506.1 - 1.9e-06 27.6 0.2 1.6 8.6 0.0 4.5 4 1 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFP17506.1 - 0.002 18.1 6.4 1.8 8.6 0.3 4.4 5 0 0 5 5 5 2 Cadherin-like GRP PF07172.11 KFP17506.1 - 0.015 16.0 0.1 0.031 15.0 0.1 1.4 1 0 0 1 1 1 0 Glycine rich protein family Cadherin_4 PF17803.1 KFP17506.1 - 0.025 15.2 2.5 0.025 15.2 2.5 3.8 5 0 0 5 5 4 0 Bacterial cadherin-like domain TAS2R PF05296.13 KFP17506.1 - 0.053 12.6 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Cadherin_pro PF08758.11 KFP17506.1 - 0.063 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Cadherin prodomain like Stevor PF17410.2 KFP17506.1 - 0.1 12.2 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame 7TM_GPCR_Srw PF10324.9 KFP17506.1 - 0.16 11.2 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Invasin_D3 PF09134.10 KFP17506.1 - 0.22 11.9 5.5 5.8 7.3 0.1 3.8 4 1 0 4 4 4 0 Invasin, domain 3 PepSY PF03413.19 KFP17506.1 - 0.28 11.7 2.1 1.3 9.7 0.0 3.1 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain TNFR_c6 PF00020.18 KFP17507.1 - 9.2e-16 58.0 37.4 4.1e-07 30.3 0.6 4.5 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region HGTP_anticodon PF03129.20 KFP17508.1 - 0.00079 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Macoilin PF09726.9 KFP17508.1 - 0.064 11.8 0.1 0.064 11.8 0.1 2.2 2 0 0 2 2 2 0 Macoilin family AA_permease PF00324.21 KFP17509.1 - 3.9e-32 111.5 20.7 2.5e-12 46.2 0.7 3.1 3 0 0 3 3 3 3 Amino acid permease SLC12 PF03522.15 KFP17509.1 - 3.4e-24 85.7 0.4 2.7e-17 62.9 0.1 2.2 2 0 0 2 2 2 2 Solute carrier family 12 Peptidase_M10 PF00413.24 KFP17510.1 - 2.8e-68 228.7 0.0 3.5e-67 225.2 0.0 2.3 2 1 0 2 2 2 1 Matrixin fn2 PF00040.19 KFP17510.1 - 3.2e-20 72.1 7.0 7.2e-20 71.0 7.0 1.6 1 0 0 1 1 1 1 Fibronectin type II domain PG_binding_1 PF01471.18 KFP17510.1 - 3e-13 49.8 0.5 6.5e-13 48.7 0.5 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Hemopexin PF00045.19 KFP17510.1 - 1.4e-05 24.9 2.6 1.7e-05 24.7 0.1 2.5 2 1 0 2 2 2 1 Hemopexin Reprolysin_4 PF13583.6 KFP17510.1 - 0.0025 17.5 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFP17510.1 - 0.0077 15.9 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP17510.1 - 0.013 16.1 0.0 0.037 14.6 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP17510.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KFP17510.1 - 0.03 13.6 0.4 0.094 11.9 0.1 1.8 2 0 0 2 2 2 0 Met-zincin Peptidase_M66 PF10462.9 KFP17510.1 - 0.078 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Homeobox_KN PF05920.11 KFP17511.1 - 2.2e-15 56.3 0.1 2.6e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP17511.1 - 7.7e-07 28.9 0.1 9.3e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP17511.1 - 0.018 14.5 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Phage_P2_GpE PF06528.12 KFP17511.1 - 0.061 12.9 0.1 0.061 12.9 0.1 1.6 2 0 0 2 2 2 0 Phage P2 GpE PCIF1_WW PF12237.8 KFP17512.1 - 2.4e-69 232.3 0.3 3.7e-69 231.7 0.3 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.26 KFP17512.1 - 5.7e-11 42.3 0.4 1.1e-10 41.4 0.4 1.5 1 0 0 1 1 1 1 WW domain SR-25 PF10500.9 KFP17512.1 - 0.15 11.6 12.6 0.37 10.4 12.6 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KFP17512.1 - 0.31 11.7 9.2 0.79 10.4 9.2 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Peptidase_S10 PF00450.22 KFP17513.1 - 1.9e-74 251.6 0.0 2.1e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Neuralized PF07177.12 KFP17514.1 - 2e-32 112.3 0.0 2.5e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Neuralized SOCS_box PF07525.16 KFP17514.1 - 4.7e-10 39.7 2.3 9.9e-10 38.6 2.3 1.5 1 0 0 1 1 1 1 SOCS box 4HBT_3 PF13622.6 KFP17515.1 - 9.1e-49 166.9 0.0 1e-48 166.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFP17515.1 - 6e-32 110.3 0.0 1.4e-27 96.1 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA thioesterase DNTTIP1_dimer PF18192.1 KFP17516.1 - 5.6e-27 93.9 0.1 8e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain LolA PF03548.15 KFP17516.1 - 0.062 13.0 0.0 2.8 7.6 0.0 2.4 2 1 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA DUF4385 PF14328.6 KFP17516.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) Myotub-related PF06602.14 KFP17517.1 - 5.7e-145 482.7 0.0 7.4e-145 482.3 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP17517.1 - 0.00043 19.9 0.0 0.00085 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFP17517.1 - 0.0021 17.6 0.2 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.8 KFP17517.1 - 0.0028 17.8 0.1 0.005 17.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DSPc PF00782.20 KFP17517.1 - 0.0033 17.2 0.1 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain GRAM PF02893.20 KFP17517.1 - 0.0052 16.7 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 GRAM domain Y_phosphatase3 PF13350.6 KFP17517.1 - 0.011 15.7 0.1 0.028 14.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF4606 PF15379.6 KFP17518.1 - 3.3e-29 101.2 0.1 3.6e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) SICA_C PF12879.7 KFP17518.1 - 0.043 13.8 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Gtr1_RagA PF04670.12 KFP17519.1 - 3.4e-108 360.4 1.2 4.1e-108 360.1 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP17519.1 - 3e-08 33.9 0.0 1.1e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP17519.1 - 3.5e-08 33.2 0.0 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP17519.1 - 2.6e-07 30.3 0.1 6.5e-07 29.0 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP17519.1 - 9.3e-07 28.9 0.0 3.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP17519.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KFP17519.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 KFP17519.1 - 0.031 13.4 1.7 0.47 9.6 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) SecA_DEAD PF07517.14 KFP17519.1 - 0.051 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain RsgA_GTPase PF03193.16 KFP17519.1 - 0.15 12.0 0.2 10 6.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KFP17519.1 - 0.18 12.3 0.1 0.31 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF5099 PF17025.5 KFP17519.1 - 2.7 8.4 6.0 18 5.8 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5099) zf-C2H2 PF00096.26 KFP17520.1 - 2.9e-14 52.6 25.4 4.4e-05 23.7 0.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP17520.1 - 1.8e-09 37.6 10.8 1.1e-05 25.6 3.5 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP17520.1 - 2.1e-06 28.1 23.4 0.044 14.6 4.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP17520.1 - 0.0075 16.9 5.9 0.35 11.5 0.2 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFP17520.1 - 0.15 11.8 5.3 0.086 12.6 2.7 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KFP17520.1 - 1.8 8.7 5.6 17 5.5 2.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger Sec3_C PF09763.9 KFP17521.1 - 6.2e-77 259.6 2.8 7.7e-77 259.3 2.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Actin_micro PF17003.5 KFP17521.1 - 2.3 7.3 7.0 0.18 10.9 2.3 1.5 2 0 0 2 2 2 0 Putative actin-like family Glyoxalase PF00903.25 KFP17522.1 - 5.8e-11 42.7 0.0 4.2e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KFP17522.1 - 0.002 18.0 0.1 0.0099 15.8 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFP17522.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFP17522.1 - 0.03 14.6 0.0 0.085 13.1 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CofC PF01983.16 KFP17522.1 - 0.074 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like MmgE_PrpD PF03972.14 KFP17523.1 - 3.6e-126 421.3 0.0 4e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Sua5_yciO_yrdC PF01300.18 KFP17524.1 - 1.3e-31 109.4 0.0 1.9e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination DJ-1_PfpI PF01965.24 KFP17525.1 - 0.00047 20.0 1.6 0.0012 18.6 1.6 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family DUF587 PF04532.12 KFP17525.1 - 0.032 13.5 0.1 0.049 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) EF-hand_1 PF00036.32 KFP17526.1 - 7.2e-26 87.8 5.0 7e-08 31.5 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP17526.1 - 5.9e-25 87.5 2.5 1.8e-14 54.0 2.7 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP17526.1 - 2.9e-21 73.5 0.9 2e-05 24.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFP17526.1 - 5.1e-16 58.3 11.3 1.6e-09 37.5 2.4 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KFP17526.1 - 1.9e-09 37.7 0.2 2.9e-06 27.5 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KFP17526.1 - 1.6e-06 27.3 15.3 0.0011 18.3 1.9 4.8 5 2 1 6 6 6 2 EF hand Dockerin_1 PF00404.18 KFP17526.1 - 5.1e-05 23.4 0.1 9.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_11 PF08976.11 KFP17526.1 - 0.0017 19.2 0.0 0.088 13.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KFP17526.1 - 0.0029 17.5 2.3 0.11 12.4 0.6 2.5 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand PhetRS_B1 PF18262.1 KFP17526.1 - 0.17 12.1 3.7 3 8.1 1.1 2.3 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_1 PF00036.32 KFP17527.1 - 6.9e-30 100.4 18.1 1.2e-08 33.9 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP17527.1 - 8.4e-28 96.6 8.9 1.4e-13 51.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP17527.1 - 2.1e-23 81.9 14.1 7.1e-12 45.0 0.7 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFP17527.1 - 4.7e-23 79.1 11.1 2.2e-08 33.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 KFP17527.1 - 2.8e-16 59.6 0.3 8.5e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP17527.1 - 2e-07 30.9 6.2 0.031 14.2 0.0 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFP17527.1 - 2.1e-07 30.1 17.9 0.0033 16.9 1.2 4.3 4 1 1 5 5 5 3 EF hand EF-hand_14 PF17959.1 KFP17527.1 - 3.4e-05 24.1 1.9 0.18 12.2 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain DUF853 PF05872.12 KFP17527.1 - 0.0043 15.7 0.5 0.018 13.7 0.3 1.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) EF-hand_11 PF08976.11 KFP17527.1 - 0.011 16.6 0.3 1.4 9.8 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KFP17527.1 - 0.013 15.8 2.0 0.87 9.9 0.7 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SUB1_ProdP9 PF18213.1 KFP17527.1 - 0.03 14.2 1.5 0.045 13.6 0.4 1.8 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 SurA_N_3 PF13624.6 KFP17527.1 - 0.033 14.0 3.5 0.89 9.3 1.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain SurA_N_2 PF13623.6 KFP17527.1 - 0.059 13.2 4.2 1.1 9.2 0.6 2.8 2 2 0 2 2 2 0 SurA N-terminal domain Dockerin_1 PF00404.18 KFP17527.1 - 0.063 13.5 0.9 0.26 11.5 0.1 2.2 2 1 0 2 2 2 0 Dockerin type I domain Gp-FAR-1 PF05823.12 KFP17527.1 - 0.4 11.0 0.2 0.4 11.0 0.2 3.0 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1542 PF07564.11 KFP17527.1 - 0.59 10.3 3.8 20 5.4 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) SRI PF08236.11 KFP17527.1 - 0.86 9.8 7.3 1.2 9.3 0.1 3.3 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DUF2757 PF10955.8 KFP17527.1 - 2.6 8.4 4.8 4.8 7.5 0.4 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2757) 3Beta_HSD PF01073.19 KFP17528.1 - 5e-70 235.7 0.0 6.1e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP17528.1 - 1.2e-37 129.7 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP17528.1 - 9.4e-20 71.3 0.0 1.2e-17 64.3 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFP17528.1 - 1.1e-15 58.0 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFP17528.1 - 1.7e-14 53.6 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFP17528.1 - 1.7e-09 37.2 0.0 0.00011 21.5 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFP17528.1 - 9.6e-08 31.5 0.0 6.9e-07 28.7 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFP17528.1 - 2.2e-07 30.7 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.15 KFP17528.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KFP17528.1 - 0.044 13.7 0.2 1.1 9.1 0.0 2.2 1 1 0 2 2 2 0 KR domain 3HCDH_N PF02737.18 KFP17528.1 - 0.087 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LIM PF00412.22 KFP17529.1 - 0.011 16.0 16.7 0.017 15.3 16.7 1.4 1 0 0 1 1 1 0 LIM domain Endonuclease_7 PF02945.15 KFP17529.1 - 0.025 14.5 7.3 0.043 13.8 7.3 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII SLAIN PF15301.6 KFP17530.1 - 4e-134 448.1 59.6 1e-113 380.9 54.0 2.4 1 1 1 2 2 2 2 SLAIN motif-containing family Synaptobrevin PF00957.21 KFP17531.1 - 6.2e-30 102.8 2.3 9.6e-30 102.2 2.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFP17531.1 - 2.8e-27 94.6 0.7 4.8e-27 93.8 0.7 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 KFP17531.1 - 0.0078 16.2 1.1 0.0099 15.8 1.1 1.2 1 0 0 1 1 1 1 Rifin RNA_pol_L_2 PF13656.6 KFP17532.1 - 3.5e-29 100.4 0.0 4.1e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFP17532.1 - 3.3e-13 48.9 0.0 4.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 7tm_1 PF00001.21 KFP17533.1 - 8.7e-36 123.6 12.6 1.2e-35 123.2 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17533.1 - 0.00024 20.6 13.4 0.0026 17.2 13.4 2.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP17533.1 - 0.027 14.2 6.9 0.035 13.8 6.9 1.2 1 0 0 1 1 1 0 Olfactory receptor HCO3_cotransp PF00955.21 KFP17534.1 - 7e-247 820.2 5.1 8.7e-247 819.9 5.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KFP17534.1 - 1.1e-105 353.3 0.0 1.5e-105 352.8 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Hormone_2 PF00123.20 KFP17535.1 - 3.3e-45 151.6 3.5 2e-14 53.1 0.4 3.3 3 0 0 3 3 3 3 Peptide hormone Lipoprotein_10 PF03202.13 KFP17535.1 - 8e-05 23.1 4.1 0.49 10.8 0.1 3.7 3 1 1 4 4 4 2 Putative mycoplasma lipoprotein, C-terminal region DPPIV_N PF00930.21 KFP17536.1 - 6.1e-99 331.1 9.0 8.6e-99 330.6 9.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP17536.1 - 2.7e-56 190.4 1.6 4.2e-56 189.8 1.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_rep PF18811.1 KFP17536.1 - 9.9e-08 31.7 0.1 2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) low complexity region Esterase_phd PF10503.9 KFP17536.1 - 3.3e-06 26.7 0.0 5.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 KFP17536.1 - 0.00036 20.1 0.2 0.0018 17.9 0.2 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 KFP17536.1 - 0.00066 19.1 0.3 0.0015 17.9 0.3 1.5 1 0 0 1 1 1 1 Secretory lipase Peptidase_S15 PF02129.18 KFP17536.1 - 0.00066 19.3 4.6 0.0012 18.5 0.6 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFP17536.1 - 0.00068 20.3 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFP17536.1 - 0.0035 17.2 1.0 0.57 9.9 0.4 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2920 PF11144.8 KFP17536.1 - 0.0041 16.3 0.7 0.07 12.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 KFP17536.1 - 0.0048 16.2 0.7 1.3 8.2 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KFP17536.1 - 0.012 15.3 0.1 0.035 13.7 0.1 1.7 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.13 KFP17536.1 - 0.018 14.7 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KFP17536.1 - 0.023 13.4 0.0 0.064 11.9 0.0 1.6 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.13 KFP17536.1 - 0.044 12.3 0.0 1.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Prot_inhib_II PF02428.15 KFP17536.1 - 0.07 13.6 1.6 0.15 12.5 1.6 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family RIG-I_C-RD PF11648.8 KFP17537.1 - 4.5e-39 133.3 3.0 4.5e-39 133.3 3.0 2.3 3 0 0 3 3 3 1 C-terminal domain of RIG-I RIG-I_C PF18119.1 KFP17537.1 - 2.5e-37 128.0 9.6 2.5e-37 128.0 9.6 2.3 2 0 0 2 2 2 1 RIG-I receptor C-terminal domain CARD_2 PF16739.5 KFP17537.1 - 5e-21 74.5 0.0 1.2e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain Helicase_C PF00271.31 KFP17537.1 - 5.6e-19 68.5 2.8 3.8e-18 65.9 0.1 3.2 4 0 0 4 4 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP17537.1 - 3.7e-18 66.1 0.0 3.7e-18 66.1 0.0 3.1 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP17537.1 - 2.1e-15 56.9 0.1 1.6e-14 54.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase CARD PF00619.21 KFP17537.1 - 7.4e-08 32.3 0.2 1.8e-07 31.1 0.2 1.7 1 0 0 1 1 1 1 Caspase recruitment domain SWI2_SNF2 PF18766.1 KFP17537.1 - 7.7e-06 25.7 0.1 3.1e-05 23.7 0.0 2.1 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 KFP17537.1 - 0.0076 16.6 0.1 1.8 8.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain DUF3638 PF12340.8 KFP17537.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) AAA_22 PF13401.6 KFP17537.1 - 0.033 14.5 0.2 0.6 10.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain Yippee-Mis18 PF03226.14 KFP17537.1 - 0.15 12.3 1.5 0.4 10.9 1.5 1.7 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ion_trans PF00520.31 KFP17538.1 - 2.6e-37 128.4 4.7 3.5e-37 127.9 4.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KFP17538.1 - 1.6e-12 47.3 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP17538.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Ion channel AAA PF00004.29 KFP17539.1 - 1.6e-24 86.8 0.0 2.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFP17539.1 - 4.5e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFP17539.1 - 6.8e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFP17539.1 - 8.9e-05 22.5 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP17539.1 - 0.0034 17.8 0.0 0.009 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KFP17539.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFP17539.1 - 0.038 14.3 0.1 0.076 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KFP17539.1 - 0.16 11.2 0.2 0.29 10.3 0.0 1.4 2 0 0 2 2 2 0 TIP49 P-loop domain BPS PF08947.10 KFP17540.1 - 5e-28 96.7 0.3 1.4e-27 95.2 0.3 1.8 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.24 KFP17540.1 - 1.2e-16 60.6 0.1 2.7e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 SH2 domain RA PF00788.23 KFP17540.1 - 5.9e-14 52.5 0.2 1.9e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KFP17540.1 - 1.6e-11 44.6 0.3 5.8e-11 42.8 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFP17540.1 - 0.09 13.1 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Aa_trans PF01490.18 KFP17541.1 - 5.1e-64 216.5 31.2 5.9e-64 216.3 31.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFP17541.1 - 3.7e-05 23.0 14.7 3.7e-05 23.0 14.7 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Neurensin PF14927.6 KFP17541.1 - 0.035 13.8 0.5 0.87 9.3 0.0 3.1 3 0 0 3 3 3 0 Neurensin DUF2427 PF10348.9 KFP17541.1 - 0.33 10.8 17.1 0.16 11.7 2.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) JSRP PF15312.6 KFP17541.1 - 0.35 10.8 1.4 0.75 9.8 0.2 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Phlebovirus_G1 PF07243.11 KFP17541.1 - 0.37 9.1 3.9 0.73 8.1 3.9 1.4 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 CSRNP_N PF16019.5 KFP17542.1 - 3.4e-104 347.5 7.4 3.4e-104 347.5 7.4 2.2 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus Nop25 PF09805.9 KFP17542.1 - 0.011 16.2 6.5 0.74 10.3 0.1 2.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Spt5_N PF11942.8 KFP17542.1 - 0.023 15.6 5.2 0.023 15.6 5.2 3.2 3 1 1 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal GOLD_2 PF13897.6 KFP17542.1 - 2.5 8.6 6.0 0.62 10.6 2.0 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Nop14 PF04147.12 KFP17542.1 - 2.9 6.0 18.5 0.061 11.5 8.2 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KFP17542.1 - 5.6 6.2 16.4 1.7 7.9 7.4 2.2 2 0 0 2 2 2 0 BUD22 Glycos_transf_2 PF00535.26 KFP17543.1 - 9.6e-35 119.9 0.0 1.7e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP17543.1 - 1.5e-24 86.7 0.6 2.4e-24 86.0 0.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KFP17543.1 - 5.1e-09 35.7 0.0 2.9e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFP17543.1 - 3.2e-06 27.2 0.0 6.8e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFP17543.1 - 0.001 18.6 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 TPR_19 PF14559.6 KFP17544.1 - 1.9e-55 185.2 56.3 6.2e-07 29.8 1.5 17.0 13 3 6 19 19 18 12 Tetratricopeptide repeat TPR_14 PF13428.6 KFP17544.1 - 2.8e-39 130.4 37.4 2.1e-05 25.0 0.0 21.0 13 5 7 22 22 22 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP17544.1 - 1e-38 128.3 75.2 8.8e-06 25.5 0.1 22.1 25 0 0 25 25 23 10 Tetratricopeptide repeat TPR_1 PF00515.28 KFP17544.1 - 3.5e-30 102.6 59.9 1.3e-05 24.7 0.1 18.2 20 0 0 20 20 18 8 Tetratricopeptide repeat TPR_16 PF13432.6 KFP17544.1 - 5.1e-30 103.8 34.6 3.2e-07 30.9 0.0 16.6 17 4 1 18 18 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP17544.1 - 2.5e-25 86.5 51.5 0.00022 21.2 0.0 15.2 17 0 0 17 17 13 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFP17544.1 - 2.5e-20 71.0 31.7 6.6e-05 22.7 0.0 13.8 14 2 2 16 16 13 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP17544.1 - 2.9e-20 72.3 57.2 0.00027 21.1 4.7 12.9 9 5 6 15 15 14 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP17544.1 - 6.2e-17 61.7 56.5 0.00028 21.1 1.9 15.5 13 3 3 16 16 15 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP17544.1 - 1e-13 50.7 39.3 2.4e-06 27.1 0.1 12.7 12 3 3 15 15 15 4 TPR repeat TPR_6 PF13174.6 KFP17544.1 - 8.7e-12 44.9 73.2 0.018 15.7 0.0 20.6 25 0 0 25 25 19 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP17544.1 - 7.5e-11 41.6 25.4 1.1 9.8 0.0 13.7 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_21 PF09976.9 KFP17544.1 - 1.9e-09 37.6 36.3 0.074 12.8 0.2 9.0 5 2 5 10 10 9 4 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KFP17544.1 - 2.2e-07 30.8 27.1 0.17 12.6 0.1 11.7 14 0 0 14 14 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP17544.1 - 2.8e-07 30.6 10.9 0.92 9.7 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFP17544.1 - 2.4e-05 23.7 42.6 0.0074 15.5 1.1 8.3 4 2 2 8 8 8 3 Tetratricopeptide repeat PknG_TPR PF16918.5 KFP17544.1 - 0.00049 18.9 7.5 2.5 6.7 0.0 5.8 5 2 2 7 7 7 2 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 KFP17544.1 - 0.0007 20.0 18.7 1.3 9.5 0.2 7.4 6 2 0 7 7 7 2 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 KFP17544.1 - 0.0009 19.7 24.1 0.048 14.1 0.7 7.6 5 2 1 7 7 7 2 Alkyl sulfatase dimerisation TPR_20 PF14561.6 KFP17544.1 - 0.0012 19.1 38.0 3.3 8.1 0.1 11.2 6 2 5 12 12 12 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KFP17544.1 - 0.0023 17.5 21.5 0.044 13.4 0.1 8.4 9 1 0 9 9 9 1 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 KFP17544.1 - 0.0047 17.0 34.9 0.052 13.6 0.1 11.3 13 0 0 13 13 12 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFP17544.1 - 0.02 14.8 37.2 5.4 7.0 0.1 12.0 15 0 0 15 15 12 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFP17544.1 - 0.035 14.2 1.2 7.9 6.5 0.1 5.2 4 1 1 5 5 4 0 Domain of Unknown Function (DUF3856) DUF2225 PF09986.9 KFP17544.1 - 0.081 12.6 26.6 0.16 11.7 0.7 7.2 7 2 1 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4441 PF14536.6 KFP17544.1 - 0.89 9.8 3.5 50 4.1 0.1 3.9 3 2 0 3 3 2 0 Domain of unknown function (DUF4441) SPOB_a PF14689.6 KFP17544.1 - 1.7 8.4 0.0 1.7 8.4 0.0 6.1 9 0 0 9 9 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain Ion_trans PF00520.31 KFP17545.1 - 4.5e-64 216.0 32.9 2.4e-55 187.4 21.6 2.6 3 0 0 3 3 3 2 Ion transport protein PKD_channel PF08016.12 KFP17545.1 - 2.2e-07 30.0 22.6 1.1e-05 24.3 0.8 3.3 2 1 1 3 3 3 3 Polycystin cation channel GPHH PF16905.5 KFP17545.1 - 1.8e-06 27.6 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFP17545.1 - 0.00029 20.4 0.6 0.00063 19.3 0.6 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ion_trans PF00520.31 KFP17546.1 - 1.3e-160 532.2 63.5 7.4e-78 261.2 18.4 3.3 3 0 0 3 3 3 3 Ion transport protein Na_trans_cytopl PF11933.8 KFP17546.1 - 2.8e-75 252.8 5.6 6.2e-75 251.7 5.6 1.5 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Na_trans_assoc PF06512.13 KFP17546.1 - 9.8e-53 179.5 7.3 9.8e-53 179.5 7.3 2.6 3 0 0 3 3 3 1 Sodium ion transport-associated ATP-synt_B PF00430.18 KFP17546.1 - 0.00051 20.1 4.7 0.0018 18.4 4.7 2.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Glyco_trans_1_2 PF13524.6 KFP17546.1 - 0.12 12.7 0.8 0.55 10.7 0.7 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Pox_A14 PF05767.12 KFP17546.1 - 1.8 8.8 9.8 9.1 6.5 0.3 4.6 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 LIM PF00412.22 KFP17547.1 - 2.9e-10 40.2 9.9 1.1e-09 38.4 9.9 2.1 1 0 0 1 1 1 1 LIM domain Galactosyl_T PF01762.21 KFP17548.1 - 1e-60 204.9 0.0 1.3e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Pkinase PF00069.25 KFP17549.1 - 8.8e-61 205.6 0.0 1.1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17549.1 - 1.4e-44 152.3 0.0 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFP17549.1 - 3.2e-22 78.5 0.1 8.2e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 KFP17549.1 - 0.00041 19.8 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP17549.1 - 0.00066 18.6 0.0 0.002 17.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase THEG4 PF15834.5 KFP17549.1 - 0.0067 16.4 0.3 0.021 14.8 0.1 1.8 2 0 0 2 2 2 1 Testis highly expressed protein 4 APH PF01636.23 KFP17549.1 - 0.064 13.2 0.0 0.63 9.9 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP17549.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP17549.1 - 0.081 11.8 0.0 0.17 10.8 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain TRAM_LAG1_CLN8 PF03798.16 KFP17550.1 - 4e-39 134.4 23.9 4.9e-39 134.1 23.9 1.1 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFP17550.1 - 4.9e-07 29.5 1.0 8.5e-07 28.7 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Spindle_Spc25 PF08234.12 KFP17551.1 - 5.9e-23 80.9 0.3 5.9e-23 80.9 0.3 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KFP17551.1 - 1.1e-05 24.4 15.5 1.5e-05 24.1 15.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4254 PF14063.6 KFP17551.1 - 0.00095 19.0 2.0 0.0021 17.9 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) DUF3584 PF12128.8 KFP17551.1 - 0.0041 14.7 13.8 0.0047 14.5 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-H PF05837.12 KFP17551.1 - 0.017 15.5 12.9 0.017 15.5 12.9 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.9 KFP17551.1 - 0.021 13.9 15.1 0.028 13.5 15.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KFP17551.1 - 0.024 14.2 8.6 0.029 13.9 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.5 KFP17551.1 - 0.051 13.1 20.1 0.068 12.6 20.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal T3SSipB PF16535.5 KFP17551.1 - 0.066 13.7 7.0 0.096 13.2 7.0 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF4407 PF14362.6 KFP17551.1 - 0.077 12.3 4.9 0.1 11.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KFP17551.1 - 0.14 12.6 3.5 0.35 11.3 3.5 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 KFP17551.1 - 0.21 10.8 10.7 0.3 10.3 10.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein Phage_GPO PF05929.11 KFP17551.1 - 0.22 11.1 7.0 0.35 10.4 7.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.13 KFP17551.1 - 0.23 11.1 12.3 0.81 9.4 8.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) COG5 PF10392.9 KFP17551.1 - 0.28 11.4 8.6 0.74 10.0 8.6 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Spectrin PF00435.21 KFP17551.1 - 0.37 11.3 13.8 0.37 11.3 12.6 1.6 1 1 0 1 1 1 0 Spectrin repeat UPF0242 PF06785.11 KFP17551.1 - 0.41 10.7 21.7 0.12 12.5 18.3 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 KFP17551.1 - 0.54 10.5 4.6 2.1 8.6 2.9 2.4 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Tox-ODYAM1 PF15642.6 KFP17551.1 - 0.58 9.1 12.3 0.88 8.5 12.3 1.4 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TPR_MLP1_2 PF07926.12 KFP17551.1 - 0.64 10.1 19.2 1.3 9.1 19.1 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KFP17551.1 - 0.74 9.9 9.9 1.1 9.3 9.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CP12 PF02672.15 KFP17551.1 - 0.79 10.5 5.6 1.8 9.3 5.6 1.6 1 0 0 1 1 1 0 CP12 domain Syntaxin-6_N PF09177.11 KFP17551.1 - 0.89 10.1 11.9 0.87 10.2 8.9 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 KFP17551.1 - 0.89 8.1 12.2 1.1 7.8 12.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AATF-Che1 PF13339.6 KFP17551.1 - 1.1 9.9 15.0 0.2 12.3 9.5 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ATP-synt_F6 PF05511.11 KFP17551.1 - 1.8 9.0 6.0 32 5.0 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 CorA PF01544.18 KFP17551.1 - 2 7.6 11.4 11 5.2 9.1 2.5 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein YtxH PF12732.7 KFP17551.1 - 3.3 8.3 8.0 50 4.5 8.0 2.6 1 1 0 1 1 1 0 YtxH-like protein DUF848 PF05852.11 KFP17551.1 - 3.6 7.7 12.5 5.1 7.2 10.8 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF16 PF01519.16 KFP17551.1 - 7.6 7.1 16.7 38 4.8 16.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 LMBR1 PF04791.16 KFP17551.1 - 9.1 5.1 11.3 12 4.7 11.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAP2 PF01569.21 KFP17552.1 - 1.3e-15 57.4 6.3 1.3e-15 57.4 6.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily ABC_membrane PF00664.23 KFP17553.1 - 5.9e-130 432.8 20.9 3.3e-74 250.0 2.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP17553.1 - 6.3e-74 247.0 0.6 1.5e-35 122.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFP17553.1 - 2e-12 47.1 2.5 4e-06 26.4 1.2 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFP17553.1 - 2e-09 37.6 0.0 0.0016 18.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFP17553.1 - 2.5e-07 31.2 0.3 0.026 14.9 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFP17553.1 - 1.2e-06 27.9 0.3 0.0039 16.5 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 KFP17553.1 - 3.8e-06 27.2 0.1 0.028 14.7 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFP17553.1 - 5.2e-06 26.4 0.1 0.056 13.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFP17553.1 - 2e-05 24.2 0.6 0.047 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFP17553.1 - 0.00024 20.9 0.3 1.1 8.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFP17553.1 - 0.00047 19.7 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 KFP17553.1 - 0.00075 18.4 0.7 1.5 7.5 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class G-alpha PF00503.20 KFP17553.1 - 0.0011 18.1 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Rad17 PF03215.15 KFP17553.1 - 0.0036 17.2 0.0 0.22 11.5 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain DUF87 PF01935.17 KFP17553.1 - 0.0041 17.2 0.6 1.5 8.9 0.1 2.6 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 KFP17553.1 - 0.0082 16.0 0.1 0.25 11.1 0.0 3.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KFP17553.1 - 0.0097 16.1 0.0 6.9 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFP17553.1 - 0.0098 16.1 0.1 10 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KFP17553.1 - 0.011 15.5 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KFP17553.1 - 0.011 15.4 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 KFP17553.1 - 0.025 14.3 0.1 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 KFP17553.1 - 0.036 14.0 0.1 3.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase SbcCD_C PF13558.6 KFP17553.1 - 0.038 14.2 3.1 2.4 8.4 0.2 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KFP17553.1 - 0.044 14.2 0.0 6.6 7.2 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KFP17553.1 - 0.099 12.2 3.6 2.7 7.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain PRK PF00485.18 KFP17553.1 - 0.14 11.9 0.1 9.6 5.9 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TssO PF17561.2 KFP17553.1 - 0.19 11.9 0.5 0.56 10.3 0.5 1.8 1 0 0 1 1 1 0 Type VI secretion system, TssO AAA_23 PF13476.6 KFP17553.1 - 0.19 12.2 0.1 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 KFP17554.1 - 3.6e-25 88.6 0.0 5.4e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP17554.1 - 1.3e-13 51.0 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFP17554.1 - 0.00017 21.1 0.0 0.00066 19.1 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFP17554.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Ldl_recept_a PF00057.18 KFP17555.1 - 0 1097.9 672.2 3e-12 46.5 9.2 38.2 38 1 0 38 38 38 36 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFP17555.1 - 6.4e-207 669.9 96.5 2.2e-11 44.0 0.0 37.7 38 0 0 38 38 38 29 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP17555.1 - 4e-56 187.0 365.0 5.6e-10 39.3 5.5 24.6 25 1 0 25 25 25 16 Coagulation Factor Xa inhibitory site DUF5050 PF16472.5 KFP17555.1 - 3.2e-36 125.0 0.2 1.6e-07 30.9 0.0 10.3 8 2 0 9 9 9 9 Domain of unknown function (DUF5050) cEGF PF12662.7 KFP17555.1 - 1.9e-29 101.2 152.0 1e-09 38.1 2.6 19.3 19 0 0 19 19 19 10 Complement Clr-like EGF-like SGL PF08450.12 KFP17555.1 - 1.4e-17 64.1 27.8 0.028 14.0 1.0 15.2 9 7 3 14 14 14 5 SMP-30/Gluconolactonase/LRE-like region EGF_CA PF07645.15 KFP17555.1 - 3.3e-12 46.4 44.0 3.7e-08 33.4 6.9 35.4 28 11 14 43 43 43 6 Calcium-binding EGF domain Arylesterase PF01731.20 KFP17555.1 - 1.8e-05 24.9 0.0 10 6.4 0.1 8.8 11 1 0 11 11 11 1 Arylesterase He_PIG PF05345.12 KFP17555.1 - 0.03 14.5 1.2 16 5.7 0.6 4.5 4 0 0 4 4 4 0 Putative Ig domain Collagen PF01391.18 KFP17556.1 - 2.1e-68 226.0 288.4 1.1e-09 37.9 24.1 11.9 2 2 5 8 8 8 7 Collagen triple helix repeat (20 copies) VWA PF00092.28 KFP17556.1 - 2.5e-68 229.8 2.1 2.1e-40 138.8 0.4 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP17556.1 - 7.1e-31 107.0 0.1 3.8e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 KFP17556.1 - 0.0004 20.4 0.1 0.007 16.3 0.0 2.6 3 1 0 3 3 3 1 von Willebrand factor type A domain BBL5 PF07289.11 KFP17557.1 - 9.6e-152 504.8 0.1 1.1e-151 504.6 0.1 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 KFP17557.1 - 9e-05 22.6 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KFP17557.1 - 0.00015 21.6 0.1 0.072 13.0 0.0 2.5 2 0 0 2 2 2 2 GRAM domain bPH_3 PF14470.6 KFP17557.1 - 0.00017 21.9 0.1 0.0059 16.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain PH_TFIIH PF08567.11 KFP17557.1 - 0.00054 20.2 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Voldacs PF03517.13 KFP17557.1 - 0.0073 16.4 1.1 1.3 9.2 0.1 2.8 2 1 1 3 3 3 2 Regulator of volume decrease after cellular swelling Kelch_1 PF01344.25 KFP17558.1 - 4e-44 147.9 0.0 1.1e-10 40.9 0.0 5.5 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KFP17558.1 - 6.5e-31 106.5 0.7 1.7e-30 105.1 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP17558.1 - 4.2e-29 99.9 0.0 2.3e-08 34.0 0.0 5.6 2 1 3 5 5 5 5 Kelch motif BTB PF00651.31 KFP17558.1 - 1.8e-28 99.0 0.5 3.9e-28 97.9 0.5 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 KFP17558.1 - 4.8e-20 71.3 0.0 1.1e-06 28.6 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP17558.1 - 2.3e-19 69.2 0.0 0.0018 18.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP17558.1 - 7.5e-18 63.7 0.1 0.064 13.3 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KFP17558.1 - 2e-13 50.0 0.0 0.28 11.2 0.0 5.4 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.8 KFP17558.1 - 0.0038 17.4 0.4 0.074 13.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) FAST_2 PF08368.12 KFP17559.1 - 2.4e-29 102.0 2.3 8.3e-27 93.8 0.0 3.5 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.15 KFP17559.1 - 2.6e-21 75.3 17.0 1.6e-18 66.4 1.9 4.7 4 0 0 4 4 4 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 KFP17559.1 - 3.1e-14 52.8 0.7 1.9e-13 50.3 0.0 2.8 3 0 0 3 3 3 1 RAP domain UPF0061 PF02696.14 KFP17559.1 - 0.38 9.5 2.7 6.6 5.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized ACR, YdiU/UPF0061 family Pro_isomerase PF00160.21 KFP17560.1 - 5.3e-48 163.3 0.2 5.3e-48 163.3 0.2 2.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 KFP17560.1 - 2.5e-07 30.5 39.8 2.5e-07 30.5 39.8 5.7 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein TPH PF13868.6 KFP17561.1 - 1.1e-18 66.9 123.7 1.1e-18 66.9 123.7 2.4 2 1 0 2 2 2 1 Trichohyalin-plectin-homology domain Put_Phosphatase PF06888.12 KFP17562.1 - 4.5e-92 307.7 0.0 5.1e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KFP17562.1 - 4e-10 40.4 0.0 2.9e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP17562.1 - 0.006 16.7 0.7 0.9 9.6 0.6 3.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP17562.1 - 0.16 12.3 0.0 2.7 8.2 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Kelch_1 PF01344.25 KFP17563.1 - 6.4e-48 160.1 31.9 5.9e-12 45.0 0.3 7.2 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KFP17563.1 - 1.6e-35 120.2 10.0 5e-09 36.1 0.1 6.4 3 2 3 6 6 6 6 Kelch motif BACK PF07707.15 KFP17563.1 - 1.3e-25 89.5 3.0 1.3e-25 89.5 3.0 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP17563.1 - 6.6e-25 86.9 5.3 4.7e-05 23.3 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFP17563.1 - 2.5e-22 79.2 1.2 4.1e-22 78.5 1.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFP17563.1 - 2.3e-21 74.8 16.3 0.00066 19.6 0.0 7.2 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP17563.1 - 1.7e-13 50.5 9.2 0.0016 18.6 0.0 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP17563.1 - 4.3e-08 33.0 21.8 0.093 12.8 0.4 6.6 7 0 0 7 7 7 4 Kelch motif RRM_3 PF08777.11 KFP17564.1 - 5.3e-28 97.1 1.8 5.3e-28 97.1 1.8 3.1 3 1 0 3 3 3 2 RNA binding motif La PF05383.17 KFP17564.1 - 6.3e-22 77.4 0.1 1.2e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFP17564.1 - 9.2e-15 54.2 0.2 2.2e-09 37.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.6 KFP17564.1 - 5 7.6 8.5 9.4 6.7 2.5 3.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) MTS PF05175.14 KFP17565.1 - 5.2e-15 55.4 0.1 7.4e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFP17565.1 - 3.1e-11 43.2 0.2 5.2e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFP17565.1 - 4.8e-10 39.4 0.1 7.2e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP17565.1 - 1.3e-09 38.7 0.4 2.8e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP17565.1 - 6.2e-09 35.7 0.0 8.4e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFP17565.1 - 7.5e-07 29.0 0.8 7.5e-06 25.8 0.8 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KFP17565.1 - 5.8e-06 26.0 0.1 8.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KFP17565.1 - 0.00019 22.1 0.1 0.00049 20.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.17 KFP17565.1 - 0.0038 16.6 0.0 0.0078 15.6 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_4 PF02390.17 KFP17565.1 - 0.0073 15.8 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase N6-adenineMlase PF10237.9 KFP17565.1 - 0.0085 15.9 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase FmrO PF07091.11 KFP17565.1 - 0.0095 15.5 0.2 0.025 14.1 0.2 1.7 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) N6_Mtase PF02384.16 KFP17565.1 - 0.012 15.0 0.6 0.024 13.9 0.5 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_16 PF10294.9 KFP17565.1 - 0.017 14.9 0.8 0.031 14.0 0.1 1.7 2 1 0 2 2 2 0 Lysine methyltransferase DUF43 PF01861.16 KFP17565.1 - 0.03 13.6 0.1 0.051 12.8 0.1 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_9 PF08003.11 KFP17565.1 - 0.046 12.7 0.5 0.064 12.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltr_RsmB-F PF01189.17 KFP17565.1 - 0.056 13.1 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F UPF0444 PF15475.6 KFP17565.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.4 2 0 0 2 2 1 0 Transmembrane protein C12orf23, UPF0444 zf-RING_5 PF14634.6 KFP17566.1 - 0.0026 17.7 0.7 0.0026 17.7 0.7 3.3 3 0 0 3 3 3 1 zinc-RING finger domain CRAL_TRIO PF00650.20 KFP17566.1 - 0.0088 15.8 0.4 0.03 14.0 0.4 2.0 1 0 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4 PF00097.25 KFP17566.1 - 0.015 15.1 0.5 0.015 15.1 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FliD_N PF02465.18 KFP17566.1 - 7.1 7.4 6.6 4 8.2 1.7 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Myosin_head PF00063.21 KFP17567.1 - 8.6e-200 665.4 3.0 1e-199 665.1 3.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.25 KFP17567.1 - 3.7e-52 177.3 0.0 6.1e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17567.1 - 1.4e-35 122.8 0.0 2.7e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP17567.1 - 2.9e-05 23.0 0.0 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP17567.1 - 6.6e-05 22.9 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family IQ PF00612.27 KFP17567.1 - 0.00017 21.1 5.8 0.01 15.5 0.0 3.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif Kinase-like PF14531.6 KFP17567.1 - 0.0002 20.8 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AAA_22 PF13401.6 KFP17567.1 - 0.023 15.0 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP17567.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KFP17567.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APH_6_hur PF04655.14 KFP17567.1 - 0.15 11.4 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase zf-C2H2 PF00096.26 KFP17568.1 - 6.3e-20 70.4 13.8 1.1e-07 31.9 0.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP17568.1 - 1.4e-17 63.2 7.4 7.2e-10 38.8 1.1 3.5 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP17568.1 - 1.7e-13 50.1 14.5 1.2e-05 25.7 1.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP17568.1 - 4.5e-06 26.5 12.6 0.0028 17.6 0.8 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP17568.1 - 1.8e-05 24.9 2.5 0.46 10.8 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KFP17568.1 - 0.0001 22.1 2.9 0.29 11.1 0.0 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-BED PF02892.15 KFP17568.1 - 0.00016 21.6 7.6 1.6 8.8 0.4 3.2 1 1 2 3 3 3 3 BED zinc finger zf-Di19 PF05605.12 KFP17568.1 - 0.00023 21.4 4.6 0.00035 20.8 2.6 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP17568.1 - 0.00041 20.6 2.5 0.00046 20.4 2.5 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KFP17568.1 - 0.0016 18.8 5.2 2.1 8.8 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFP17568.1 - 0.0017 19.0 5.3 0.25 12.0 0.3 3.0 1 1 2 3 3 3 1 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 KFP17568.1 - 0.0028 17.2 5.3 0.22 11.2 0.1 2.8 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 KFP17568.1 - 0.0036 17.2 2.0 1.5 8.8 0.1 3.0 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KFP17568.1 - 0.0044 16.6 1.9 0.089 12.4 0.1 2.9 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KFP17568.1 - 0.019 14.7 0.1 0.019 14.7 0.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KFP17568.1 - 0.021 15.5 3.1 4.6 7.9 0.2 2.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ogr_Delta PF04606.12 KFP17568.1 - 0.024 14.6 0.2 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2HE PF16278.5 KFP17568.1 - 0.031 14.7 10.4 3.7 8.1 0.3 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KFP17568.1 - 0.052 13.7 1.5 0.18 11.9 1.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain XPA_N PF01286.18 KFP17568.1 - 0.058 13.4 0.9 0.49 10.5 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_9 PF14369.6 KFP17568.1 - 0.06 13.6 1.4 0.087 13.1 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_2 PF12756.7 KFP17568.1 - 0.06 13.7 3.8 5.5 7.4 0.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KFP17568.1 - 0.068 13.0 0.3 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFP17568.1 - 0.073 13.6 7.7 3.9 8.0 2.9 3.4 3 2 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain ADK_lid PF05191.14 KFP17568.1 - 0.1 12.6 1.9 1.4 9.0 0.2 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 KFP17568.1 - 0.13 11.7 1.2 0.88 9.1 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain DUF1610 PF07754.11 KFP17568.1 - 0.13 12.2 0.6 0.13 12.2 0.6 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.7 KFP17568.1 - 0.14 12.1 0.5 0.14 12.1 0.5 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain FYDLN_acid PF09538.10 KFP17568.1 - 0.42 11.3 1.5 1.6 9.5 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_11 PF16622.5 KFP17568.1 - 3.7 7.4 8.5 2.4 8.0 0.6 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Pyridoxal_deC PF00282.19 KFP17569.1 - 4.8e-152 506.0 0.0 5.6e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFP17569.1 - 1.7e-05 24.3 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KFP17569.1 - 1.7e-05 24.0 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFP17569.1 - 0.0056 16.0 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KFP17569.1 - 0.0093 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OKR_DC_1 PF01276.20 KFP17569.1 - 0.029 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 KFP17569.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II GRASP55_65 PF04495.14 KFP17570.1 - 6e-70 233.9 0.0 2.4e-54 183.4 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KFP17570.1 - 2.5e-08 33.6 0.0 0.0032 17.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP17570.1 - 8.9e-07 29.1 0.0 0.044 14.1 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 KFP17570.1 - 0.14 12.5 0.0 32 5.0 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Pkinase PF00069.25 KFP17571.1 - 1.5e-61 208.1 0.0 1.5e-61 208.1 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17571.1 - 2.3e-34 118.8 0.0 5.4e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Vir_act_alpha_C PF10400.9 KFP17571.1 - 3.5 8.4 16.9 2.4 8.9 3.5 3.7 3 1 0 3 3 3 0 Virulence activator alpha C-term Methyltransf_25 PF13649.6 KFP17572.1 - 8.4e-13 48.9 0.1 3.4e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP17572.1 - 2.1e-12 47.2 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP17572.1 - 2.5e-11 44.2 0.1 6.6e-11 42.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP17572.1 - 6.1e-11 42.8 0.0 1.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP17572.1 - 9.1e-06 25.5 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KFP17572.1 - 0.013 15.0 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.6 KFP17572.1 - 0.023 15.7 0.0 0.072 14.1 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain NodS PF05401.11 KFP17572.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 KFP17572.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Trypan_glycop PF00913.19 KFP17572.1 - 0.2 10.9 0.8 0.27 10.5 0.8 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Gal-bind_lectin PF00337.22 KFP17572.1 - 0.89 9.1 3.7 1.7 8.2 3.7 1.6 1 1 0 1 1 1 0 Galactoside-binding lectin DCAF17 PF15802.5 KFP17573.1 - 3.3e-223 741.7 0.2 3.8e-223 741.5 0.2 1.0 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 17 Cytochrom_B561 PF03188.16 KFP17574.1 - 1.7e-38 131.9 9.0 2.6e-38 131.3 9.0 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF373 PF04123.13 KFP17574.1 - 1.4 8.3 4.8 0.67 9.3 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PepSY_TM PF03929.16 KFP17574.1 - 7.5 6.1 8.1 16 5.1 0.0 3.0 3 0 0 3 3 3 0 PepSY-associated TM region Dynein_IC2 PF11540.8 KFP17575.1 - 3.4e-15 55.7 0.6 7.2e-15 54.6 0.6 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 KFP17575.1 - 1.9e-07 31.7 10.3 0.096 13.6 0.3 7.1 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17575.1 - 0.0012 19.1 0.0 0.028 14.7 0.0 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain LigA PF07746.11 KFP17575.1 - 0.25 11.5 1.3 0.42 10.8 0.6 1.7 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit MAT1 PF06391.13 KFP17575.1 - 0.32 10.8 15.5 2.2 8.0 7.5 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Mito_carr PF00153.27 KFP17576.1 - 3.9e-73 241.5 0.4 1.2e-25 89.3 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFP17576.1 - 1.6e-12 46.0 2.3 0.012 15.1 0.1 5.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP17576.1 - 2.3e-11 42.6 2.9 0.01 15.7 0.1 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KFP17576.1 - 8.5e-11 42.2 1.7 0.0016 18.8 0.0 4.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFP17576.1 - 4e-06 26.6 0.2 0.0025 17.6 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP17576.1 - 8.9e-05 21.8 0.5 2.3 7.9 0.0 4.0 3 0 0 3 3 3 2 EF hand DUF4734 PF15881.5 KFP17576.1 - 0.12 12.6 0.8 0.31 11.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Hat1_N PF10394.9 KFP17577.1 - 5.3e-33 114.5 0.7 3.9e-32 111.7 0.6 2.3 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KFP17577.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KFP17577.1 - 0.03 14.0 0.2 0.047 13.3 0.2 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_10 PF13673.7 KFP17577.1 - 0.03 14.2 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP17577.1 - 0.039 14.4 0.0 0.093 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M24 PF00557.24 KFP17578.1 - 1.2e-55 188.4 0.0 1.5e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Integrin_alpha2 PF08441.12 KFP17579.1 - 1.7e-128 429.5 2.9 2.1e-128 429.1 2.9 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFP17579.1 - 1.5e-18 66.6 25.9 2.2e-09 37.3 6.7 4.3 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 KFP17579.1 - 2.1e-13 50.7 10.0 1.1e-09 38.8 2.4 3.2 1 1 2 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BCDHK_Adom3 PF10436.9 KFP17580.1 - 2.2e-48 164.2 0.0 3.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFP17580.1 - 2.2e-14 53.9 0.0 3.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP17580.1 - 0.00039 20.3 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDZ_5 PF17817.1 KFP17581.1 - 4.6e-28 97.3 4.1 2.5e-27 95.0 4.1 2.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP17581.1 - 1.1e-13 51.4 1.9 3.1e-13 49.9 1.9 1.9 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KFP17581.1 - 1.5e-08 34.6 0.4 3.7e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP17581.1 - 1.6e-07 31.6 2.2 2.7e-07 30.9 0.9 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFP17581.1 - 5.3e-05 23.0 0.2 0.00031 20.5 0.1 2.3 2 0 0 2 2 2 1 PDZ domain SAM_PNT PF02198.16 KFP17581.1 - 0.0018 18.2 1.6 0.004 17.1 1.6 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PDZ_2 PF13180.6 KFP17581.1 - 0.015 15.6 0.3 0.051 13.9 0.3 1.9 1 0 0 1 1 1 0 PDZ domain DUF2407_C PF13373.6 KFP17581.1 - 0.22 11.7 3.6 0.81 9.9 3.6 2.0 1 0 0 1 1 1 0 DUF2407 C-terminal domain Atg14 PF10186.9 KFP17581.1 - 0.92 8.5 17.2 1.9 7.5 17.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5339 PF17274.2 KFP17581.1 - 1.5 9.8 12.6 4 8.4 5.9 3.3 1 1 1 2 2 2 0 Family of unknown function (DUF5339) DUF3450 PF11932.8 KFP17581.1 - 6.2 6.1 19.5 16 4.7 18.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) RasGEF PF00617.19 KFP17582.1 - 1.5e-52 178.4 2.0 3.3e-52 177.2 2.0 1.6 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 KFP17582.1 - 2.5e-36 123.6 0.0 4.6e-16 58.7 0.0 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DEP PF00610.21 KFP17582.1 - 2.4e-22 78.7 2.5 1e-21 76.8 1.3 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.20 KFP17582.1 - 6.4e-12 45.6 0.0 1.9e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFP17582.1 - 0.042 14.5 0.0 0.14 12.8 0.0 1.9 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Pkinase_Tyr PF07714.17 KFP17583.1 - 2.8e-63 213.6 0.0 4.3e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP17583.1 - 5.5e-56 189.9 0.0 1e-55 189.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 KFP17583.1 - 7.3e-09 35.9 4.5 1.2e-08 35.3 0.4 3.2 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP17583.1 - 4.2e-08 33.2 0.1 1e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP17583.1 - 0.0012 18.7 0.1 0.0047 16.9 0.1 2.0 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 KFP17583.1 - 0.058 13.4 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF3552 PF12072.8 KFP17583.1 - 1 8.7 4.0 1.7 8.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 KFP17583.1 - 1.7 9.1 8.1 0.15 12.6 3.2 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-4CXXC_R1 PF10497.9 KFP17584.1 - 3.5e-36 123.4 10.2 6.7e-36 122.5 10.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 YL1 PF05764.13 KFP17584.1 - 0.37 10.9 8.4 0.63 10.1 8.4 1.5 1 1 0 1 1 1 0 YL1 nuclear protein zf-H2C2_2 PF13465.6 KFP17585.1 - 2.2e-13 50.0 22.8 1.2e-07 31.9 2.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP17585.1 - 2.7e-13 49.6 28.1 2e-05 24.8 2.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17585.1 - 8e-06 26.3 30.3 0.00081 20.0 1.8 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFP17585.1 - 0.0089 16.3 2.2 0.0089 16.3 2.2 2.8 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFP17585.1 - 0.013 15.4 15.3 0.15 12.1 1.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP17585.1 - 0.12 12.7 6.5 0.13 12.6 4.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP17585.1 - 0.14 12.5 4.8 1.7 9.1 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFP17585.1 - 0.27 10.9 2.3 4.2 7.1 0.7 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain YchF-GTPase_C PF06071.13 KFP17586.1 - 6.1e-42 141.7 0.4 2.2e-41 139.9 0.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFP17586.1 - 1.9e-23 82.7 0.0 5.7e-23 81.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP17586.1 - 2e-07 30.6 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KFP17586.1 - 0.0037 17.3 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MeaB PF03308.16 KFP17586.1 - 0.0059 15.6 0.2 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KFP17586.1 - 0.013 15.8 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KFP17586.1 - 0.074 13.1 0.0 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KFP17586.1 - 0.086 13.4 0.0 0.77 10.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain Cir_N PF10197.9 KFP17588.1 - 4.9e-06 26.6 4.6 9.2e-06 25.7 4.6 1.5 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR Peptidase_C69 PF03577.15 KFP17589.1 - 1.6e-08 33.9 0.1 2.3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KFP17589.1 - 0.0036 17.0 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Ca_bind_SSO6904 PF18249.1 KFP17589.1 - 0.0086 16.4 0.3 8.7 6.8 0.0 3.0 3 0 0 3 3 3 2 Calcium binding protein SSO6904 Mem_trans PF03547.18 KFP17590.1 - 7.3e-20 70.7 31.0 1.1e-13 50.4 6.7 3.2 2 1 1 3 3 3 2 Membrane transport protein DEP PF00610.21 KFP17590.1 - 7.5e-12 45.1 0.0 1.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Neur_chan_LBD PF02931.23 KFP17591.1 - 2.3e-71 239.7 1.5 3.1e-71 239.3 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP17591.1 - 3.2e-69 233.6 12.4 2.8e-53 181.4 9.6 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 KFP17591.1 - 1.3 7.3 8.2 2.2 6.5 8.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2207 PF09972.9 KFP17591.1 - 1.6 7.4 4.8 17 4.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RhoGAP PF00620.27 KFP17592.1 - 2.7e-50 170.1 0.0 4.7e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFP17592.1 - 3.8e-16 58.7 7.5 6.8e-16 57.9 7.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.24 KFP17592.1 - 5.7e-14 52.0 0.1 1.4e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FYVE_2 PF02318.16 KFP17592.1 - 0.04 14.1 2.0 0.076 13.2 2.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.6 KFP17592.1 - 0.066 12.8 1.6 0.15 11.7 1.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KFP17592.1 - 0.27 11.6 5.1 0.57 10.5 5.1 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KFP17592.1 - 3 7.8 7.6 5.9 6.9 7.6 1.5 1 0 0 1 1 1 0 PHD-finger bZIP_1 PF00170.21 KFP17593.1 - 3.2e-12 46.4 7.0 5e-12 45.7 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP17593.1 - 4.3e-09 36.3 7.7 9.3e-09 35.2 7.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP17593.1 - 0.0047 17.4 7.7 0.011 16.2 7.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor zf-C2H2 PF00096.26 KFP17593.1 - 0.028 14.9 1.5 0.054 14.0 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type KxDL PF10241.9 KFP17593.1 - 0.79 10.0 3.0 2.1 8.7 1.8 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein ATP-synt_C PF00137.21 KFP17594.1 - 1.3e-11 44.7 12.4 1.8e-11 44.2 12.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit C zinc_ribbon_10 PF10058.9 KFP17595.1 - 1.6e-21 75.8 0.3 2.4e-21 75.2 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4153 PF13687.6 KFP17595.1 - 0.0022 17.6 0.3 0.0036 17.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4153) DUF2207 PF09972.9 KFP17595.1 - 0.011 14.6 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3528 PF12045.8 KFP17597.1 - 5.6e-61 205.3 0.5 9.3e-61 204.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeodomain PF00046.29 KFP17597.1 - 2.2e-20 72.2 8.3 4e-20 71.4 8.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP17597.1 - 0.021 14.7 0.6 0.069 13.1 0.6 1.9 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 KFP17598.1 - 1.5e-20 72.8 9.6 1.7e-20 72.6 6.1 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP17598.1 - 0.013 15.4 1.8 0.031 14.2 0.3 2.4 2 0 0 2 2 2 0 Homeobox KN domain Histone PF00125.24 KFP17598.1 - 0.41 11.0 4.3 1.8 8.9 0.0 2.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Homeodomain PF00046.29 KFP17599.1 - 2.7e-22 78.3 9.1 5e-22 77.5 9.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP17599.1 - 0.068 13.1 0.9 0.14 12.1 0.9 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 KFP17599.1 - 0.077 13.3 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Tom37 PF10568.9 KFP17600.1 - 2.9e-30 105.2 0.1 1.1e-29 103.3 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KFP17600.1 - 1.1e-24 87.0 0.0 2.1e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFP17600.1 - 1.3e-24 85.8 0.2 3.6e-24 84.3 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP17600.1 - 7.2e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP17600.1 - 0.04 14.1 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain 7tm_4 PF13853.6 KFP17605.1 - 8.4e-46 156.9 7.4 9.8e-46 156.7 7.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP17605.1 - 1.3e-23 83.7 11.0 3e-23 82.5 11.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP17606.1 - 3e-48 164.9 10.6 3.5e-48 164.7 10.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP17606.1 - 1.7e-29 103.0 12.3 2.4e-29 102.5 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17606.1 - 3e-05 23.5 5.8 3e-05 23.5 5.8 2.0 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP17606.1 - 0.047 13.3 9.8 0.076 12.6 9.1 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP17607.1 - 2.1e-44 152.3 12.2 2.5e-44 152.1 12.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP17607.1 - 1.9e-28 99.6 11.4 3e-28 98.9 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP17607.1 - 0.082 12.9 0.5 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal DEAD PF00270.29 KFP17609.1 - 1.5e-46 158.4 0.1 3.3e-46 157.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP17609.1 - 3.2e-24 85.4 0.0 9.4e-23 80.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFP17609.1 - 1.6e-17 63.5 0.3 2.8e-17 62.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFP17609.1 - 2.7e-07 30.8 0.0 4.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.10 KFP17609.1 - 0.15 12.4 3.9 0.33 11.4 3.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain 7tm_1 PF00001.21 KFP17611.1 - 6.4e-69 232.2 10.1 8e-69 231.9 10.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP17611.1 - 2.1e-07 30.8 2.7 2.1e-07 30.8 2.7 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP17611.1 - 1e-05 25.1 5.2 2.8e-05 23.6 5.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP17611.1 - 0.005 16.6 1.9 0.005 16.6 1.9 1.7 2 0 0 2 2 2 1 Olfactory receptor DUF2208 PF09973.9 KFP17611.1 - 0.015 15.0 2.5 0.017 14.7 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) OppC_N PF12911.7 KFP17611.1 - 0.032 14.2 3.4 0.058 13.4 0.1 2.7 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MBOAT_2 PF13813.6 KFP17612.1 - 0.18 12.1 2.7 0.13 12.5 1.1 1.7 1 1 1 2 2 2 0 Membrane bound O-acyl transferase family KOG2701 PF09762.9 KFP17613.1 - 5e-77 258.1 0.0 5e-77 258.1 0.0 4.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein (DUF2037) Baculo_PEP_C PF04513.12 KFP17613.1 - 0.073 13.1 12.4 2.4 8.2 6.7 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MerR-DNA-bind PF09278.11 KFP17613.1 - 2 9.0 18.7 0.3 11.7 2.0 4.3 3 0 0 3 3 3 0 MerR, DNA binding NPV_P10 PF05531.12 KFP17613.1 - 4.3 7.9 13.1 24 5.5 7.8 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 KFP17613.1 - 6.6 6.9 22.4 0.36 11.0 1.0 4.8 4 1 0 5 5 5 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 KFP17613.1 - 9.5 6.3 23.7 1.1 9.3 1.4 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) INSIG PF07281.12 KFP17614.1 - 2.8e-37 128.4 3.8 2.9e-36 125.1 3.8 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Collagen PF01391.18 KFP17615.1 - 4.1e-40 135.4 125.9 1.9e-09 37.2 26.6 5.4 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) SRCR PF00530.18 KFP17615.1 - 6.9e-28 97.1 0.7 1.2e-27 96.3 0.7 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP17615.1 - 5.8e-07 30.0 0.4 1.5e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Tmemb_9 PF05434.11 KFP17615.1 - 0.0054 16.6 0.3 0.0077 16.1 0.3 1.1 1 0 0 1 1 1 1 TMEM9 MHC2-interact PF09307.10 KFP17615.1 - 0.014 15.4 1.2 0.021 14.8 0.2 1.7 1 1 1 2 2 2 0 CLIP, MHC2 interacting C1q PF00386.21 KFP17616.1 - 6.1e-13 49.1 0.0 6.4e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.18 KFP17616.1 - 0.025 14.5 0.0 0.026 14.5 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family F420_oxidored PF03807.17 KFP17617.1 - 9.1e-16 58.2 0.1 4.2e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 KFP17617.1 - 1.4e-14 54.2 5.4 3e-13 50.0 3.4 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_2 PF03446.15 KFP17617.1 - 0.0003 21.0 0.0 0.0022 18.2 0.0 2.0 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFP17617.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KFP17617.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cyclophil_like PF04126.13 KFP17617.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like Shikimate_DH PF01488.20 KFP17617.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2340 PF10209.9 KFP17618.1 - 2.4e-44 150.7 0.0 2.6e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF5049 PF16468.5 KFP17618.1 - 0.17 11.8 0.7 3 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) TMEM37 PF15108.6 KFP17619.1 - 4.6e-91 303.7 13.4 5.1e-91 303.5 13.4 1.0 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family 7tm_2 PF00002.24 KFP17620.1 - 1e-89 300.1 17.3 1.3e-89 299.7 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP17620.1 - 1.9e-20 72.9 4.7 1.9e-20 72.9 4.7 2.1 2 0 0 2 2 2 1 Hormone receptor domain Insulin_TMD PF17870.1 KFP17620.1 - 0.087 12.9 0.3 0.087 12.9 0.3 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PapD-like PF14874.6 KFP17623.1 - 1.2e-05 25.4 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 KFP17623.1 - 0.0013 18.9 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 131-like ASH PF15780.5 KFP17623.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TackOD1 PF18551.1 KFP17624.1 - 0.085 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 SMP_LBD PF17047.5 KFP17625.1 - 3e-65 219.1 0.2 1e-64 217.3 0.3 1.9 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 KFP17625.1 - 5.8e-51 171.1 1.2 1.3e-21 76.8 0.0 3.5 3 0 0 3 3 3 3 C2 domain cPLA2_C2 PF18695.1 KFP17625.1 - 0.12 12.4 1.3 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain AAA_24 PF13479.6 KFP17626.1 - 0.032 14.0 1.4 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain CoA_transf_3 PF02515.17 KFP17626.1 - 0.099 11.7 3.6 0.22 10.6 3.6 1.5 1 0 0 1 1 1 0 CoA-transferase family III UPF0184 PF03670.13 KFP17626.1 - 0.88 10.0 7.5 0.22 11.9 0.7 3.4 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) Fez1 PF06818.15 KFP17626.1 - 4.4 7.7 36.5 4.7 7.6 19.5 2.5 2 0 0 2 2 2 0 Fez1 FAIM1 PF06905.13 KFP17627.1 - 5.9e-88 293.1 2.8 6.6e-88 292.9 2.8 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF3748 PF12566.8 KFP17627.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) GP88 PF17338.2 KFP17627.1 - 0.043 13.3 0.0 0.068 12.6 0.0 1.3 1 1 0 1 1 1 0 Gene product 88 MipZ PF09140.11 KFP17627.1 - 0.087 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ DUF5640 PF18692.1 KFP17627.1 - 0.19 11.8 2.8 1.2 9.2 0.6 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5640) RRM_occluded PF16842.5 KFP17628.1 - 0.028 14.3 0.0 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_occluded PF16842.5 KFP17629.1 - 6.1e-06 26.0 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif NID PF07292.13 KFP17629.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.7 1 1 0 1 1 1 0 Nmi/IFP 35 domain (NID) GBR_NSP5 PF17580.2 KFP17629.1 - 0.027 14.3 0.3 0.036 13.9 0.3 1.1 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 BOP1NT PF08145.12 KFP17629.1 - 0.033 14.1 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain WWE PF02825.20 KFP17630.1 - 9.9e-06 26.1 1.6 9.6e-05 22.9 0.0 2.8 3 1 0 3 3 3 1 WWE domain RapH_N PF18801.1 KFP17630.1 - 0.0072 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 response regulator aspartate phosphatase H, N terminal IL17R_fnIII_D1 PF16556.5 KFP17630.1 - 0.014 15.0 0.2 2.5 7.7 0.0 2.3 1 1 1 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 YqgF PF14639.6 KFP17630.1 - 0.052 13.3 0.6 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 LSM PF01423.22 KFP17630.1 - 0.12 12.1 1.6 0.33 10.7 0.1 2.3 2 0 0 2 2 2 0 LSM domain Peptidase_M8 PF01457.16 KFP17631.1 - 5e-49 167.4 14.0 2.5e-33 115.6 0.1 3.9 2 1 1 3 3 3 3 Leishmanolysin NAD_Gly3P_dh_C PF07479.14 KFP17632.1 - 9.2e-50 168.6 0.4 3.1e-49 166.9 0.1 2.0 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFP17632.1 - 2.6e-46 157.5 0.1 6.4e-46 156.2 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF643 PF04867.12 KFP17632.1 - 0.027 15.1 0.1 0.12 13.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF643) GerD PF17898.1 KFP17632.1 - 0.054 13.5 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain Oxysterol_BP PF01237.18 KFP17634.1 - 1e-82 278.0 4.2 6.1e-81 272.1 4.2 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFP17634.1 - 1.7e-12 47.8 0.0 3.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFP17634.1 - 1.8e-08 34.5 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KFP17634.1 - 2.7e-05 24.4 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFP17634.1 - 0.0051 17.2 0.1 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KFP17634.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KFP17634.1 - 0.15 12.5 1.0 1.4 9.3 0.3 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain PX PF00787.24 KFP17635.1 - 2.1e-23 82.5 0.1 5e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFP17635.1 - 1.3e-05 24.9 10.9 0.003 17.1 10.9 2.2 1 1 0 1 1 1 1 Vps5 C terminal like FlgM PF04316.13 KFP17635.1 - 0.065 13.6 0.2 0.2 12.1 0.2 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Indigoidine_A PF04227.12 KFP17635.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein Med9 PF07544.13 KFP17635.1 - 0.94 9.6 4.1 4.2 7.5 4.1 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 zf-H2C2_2 PF13465.6 KFP17636.1 - 3.4e-22 77.8 22.3 4.2e-07 30.1 0.3 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP17636.1 - 1.4e-12 47.3 37.8 0.00032 21.0 4.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17636.1 - 3.9e-09 36.6 34.1 0.025 15.4 1.0 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger DNA_RNApol_7kD PF03604.13 KFP17636.1 - 0.39 10.4 1.7 1.2 8.8 0.3 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz PF12171.8 KFP17636.1 - 0.4 11.0 15.3 3.1 8.2 2.2 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KFP17636.1 - 1.1 9.3 7.7 10 6.3 1.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KFP17636.1 - 4.2 8.2 9.2 22 5.9 1.4 2.6 1 1 0 2 2 2 0 zinc-ribbon family AA_permease PF00324.21 KFP17637.1 - 4.4e-43 147.6 36.8 4.4e-43 147.6 36.8 2.0 2 0 0 2 2 2 1 Amino acid permease EGF_CA PF07645.15 KFP17638.1 - 4.7e-08 33.1 3.8 4.7e-08 33.1 3.8 4.5 3 1 2 5 5 5 2 Calcium-binding EGF domain EGF PF00008.27 KFP17638.1 - 0.00011 22.4 3.9 0.00011 22.4 3.9 4.3 3 2 1 4 4 4 2 EGF-like domain EGF_MSP1_1 PF12946.7 KFP17638.1 - 0.00012 22.0 23.6 0.00021 21.2 6.9 3.6 2 1 1 3 3 3 2 MSP1 EGF domain 1 FXa_inhibition PF14670.6 KFP17638.1 - 0.004 17.4 4.5 0.004 17.4 4.5 4.8 2 2 1 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP17638.1 - 0.0044 17.2 16.7 0.0095 16.1 6.7 3.6 3 1 1 4 4 4 2 EGF domain hEGF PF12661.7 KFP17638.1 - 0.0045 17.6 2.0 0.0045 17.6 2.0 4.9 5 0 0 5 5 5 2 Human growth factor-like EGF Orthoreo_P10 PF07204.11 KFP17638.1 - 0.014 15.3 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EB PF01683.18 KFP17638.1 - 0.16 12.3 31.1 0.16 12.3 4.0 4.3 2 2 2 4 4 4 0 EB module Integrin_beta PF00362.18 KFP17641.1 - 7.8e-104 346.7 0.0 1.2e-103 346.1 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_B_tail PF07965.12 KFP17641.1 - 8.7e-18 64.6 5.6 8.7e-18 64.6 5.6 4.5 3 1 2 5 5 5 1 Integrin beta tail domain Integrin_b_cyt PF08725.11 KFP17641.1 - 6.2e-17 61.0 0.2 6.2e-17 61.0 0.2 1.9 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.3 KFP17641.1 - 9.5e-14 50.9 8.2 9.5e-14 50.9 8.2 4.6 4 0 0 4 4 4 1 Integrin plexin domain I-EGF_1 PF18372.1 KFP17641.1 - 4.7e-09 36.2 8.7 4.7e-09 36.2 8.7 6.0 6 0 0 6 6 6 3 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFP17641.1 - 1.1e-07 32.1 96.5 0.00028 21.2 15.8 6.0 5 1 0 5 5 5 4 EGF-like domain DUF2975 PF11188.8 KFP17641.1 - 0.17 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Spectrin PF00435.21 KFP17644.1 - 1.4e-44 150.8 82.9 1.5e-10 41.5 2.2 9.6 7 2 1 8 8 8 6 Spectrin repeat RhoGEF PF00621.20 KFP17644.1 - 2.3e-36 125.8 0.5 2.3e-36 125.8 0.5 4.9 3 1 2 5 5 4 1 RhoGEF domain CRAL_TRIO_2 PF13716.6 KFP17644.1 - 1.6e-07 31.5 0.0 6.3e-06 26.4 0.0 3.2 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain SH3_1 PF00018.28 KFP17644.1 - 2e-07 30.5 0.0 6.3e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP17644.1 - 3.7e-07 29.9 0.2 1.4e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain CRAL_TRIO PF00650.20 KFP17644.1 - 6.5e-07 29.2 0.0 3.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO domain PH PF00169.29 KFP17644.1 - 8.7e-07 29.4 0.9 4.1e-06 27.2 0.2 2.6 2 0 0 2 2 2 1 PH domain SH3_2 PF07653.17 KFP17644.1 - 0.00074 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3-RhoG_link PF16609.5 KFP17644.1 - 0.0013 18.6 0.4 0.0027 17.5 0.4 1.6 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region PH_10 PF15411.6 KFP17644.1 - 0.0024 18.1 0.2 0.016 15.4 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain T4_Rnl2_C PF18043.1 KFP17644.1 - 0.01 15.9 2.0 0.018 15.2 0.1 2.5 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal Exonuc_VII_S PF02609.16 KFP17644.1 - 2.7 8.1 6.3 3.8 7.6 0.2 3.8 3 0 0 3 3 3 0 Exonuclease VII small subunit Nod1 PF17114.5 KFP17644.1 - 6.8 6.8 10.2 3.3 7.8 0.9 4.3 3 1 1 4 4 4 0 Gef2-related medial cortical node protein Nod1 CCDC14 PF15254.6 KFP17646.1 - 0 1175.1 38.2 0 1175.0 38.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 NEMO PF11577.8 KFP17646.1 - 2.2 8.3 16.3 6.1 6.9 0.8 2.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO I-set PF07679.16 KFP17647.1 - 7.4e-211 683.0 9.6 3.7e-28 97.4 0.1 10.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP17647.1 - 2.7e-129 422.0 10.0 2.9e-15 56.6 0.0 10.4 10 0 0 10 10 10 9 Immunoglobulin domain ig PF00047.25 KFP17647.1 - 6.5e-90 295.4 10.3 1.3e-10 41.3 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin domain Ig_2 PF13895.6 KFP17647.1 - 6.3e-81 266.8 13.3 8.3e-11 42.1 0.0 9.9 10 0 0 10 10 10 9 Immunoglobulin domain Pkinase PF00069.25 KFP17647.1 - 5.6e-77 258.7 0.0 1.1e-76 257.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain 23ISL PF16620.5 KFP17647.1 - 1.1e-50 171.9 16.3 1.1e-50 171.9 16.3 3.3 2 1 0 2 2 1 1 Unstructured linker between I-set domains 2 and 3 on MYLCK V-set PF07686.17 KFP17647.1 - 6.8e-40 135.6 24.9 4.6e-05 23.6 0.2 16.1 10 8 3 13 13 12 9 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 KFP17647.1 - 1.8e-35 122.5 0.0 3.2e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.12 KFP17647.1 - 1.5e-25 89.0 3.6 0.014 15.5 0.0 9.0 8 0 0 8 8 8 7 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KFP17647.1 - 1.4e-16 60.6 0.3 5.4e-16 58.7 0.3 2.1 1 0 0 1 1 1 1 Fibronectin type III domain BiPBP_C PF06832.12 KFP17647.1 - 1.9e-10 40.6 0.0 4.6 7.4 0.0 7.9 8 0 0 8 8 8 1 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 KFP17647.1 - 2.3e-10 40.6 2.1 0.66 10.2 0.0 7.8 9 0 0 9 9 9 2 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFP17647.1 - 5.8e-10 38.6 0.3 0.3 10.7 0.0 6.9 7 0 0 7 7 7 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP17647.1 - 2.4e-09 37.1 0.4 1.5 8.9 0.0 7.5 10 0 0 10 10 7 2 C17orf99 Ig domain Ig_4 PF16680.5 KFP17647.1 - 3.5e-08 33.6 13.4 1.4 9.3 0.0 8.7 9 0 0 9 9 9 2 T-cell surface glycoprotein CD3 delta chain Herpes_gE PF02480.16 KFP17647.1 - 1.4e-07 30.7 0.1 0.014 14.1 0.0 5.4 6 0 0 6 6 6 1 Alphaherpesvirus glycoprotein E Izumo-Ig PF16706.5 KFP17647.1 - 1.1e-05 25.3 13.2 0.52 10.4 0.0 8.2 9 0 0 9 9 9 2 Izumo-like Immunoglobulin domain Kinase-like PF14531.6 KFP17647.1 - 0.00035 20.0 0.0 0.0015 18.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP17647.1 - 0.024 14.0 0.1 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP17647.1 - 0.04 13.5 0.1 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 RIO1 family V-set_CD47 PF08204.11 KFP17647.1 - 0.13 12.3 7.8 18 5.3 0.0 5.7 7 0 0 7 7 6 0 CD47 immunoglobulin-like domain NitrOD5 PF11537.8 KFP17650.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 PTPLA PF04387.14 KFP17651.1 - 3e-53 179.9 13.0 3.3e-53 179.8 13.0 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Guanylate_cyc PF00211.20 KFP17652.1 - 3.4e-122 404.9 3.0 1.2e-62 210.8 0.5 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 KFP17652.1 - 9.6e-57 193.0 3.8 9.6e-57 193.0 3.8 2.2 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF1053 PF06327.14 KFP17652.1 - 1.7e-25 89.5 0.4 4.9e-25 88.1 0.4 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.14 KFP17652.1 - 0.0014 18.1 1.2 0.4 10.1 0.1 2.5 2 0 0 2 2 2 2 Heme NO binding associated TBK1_ULD PF18396.1 KFP17652.1 - 0.021 14.7 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Longin PF13774.6 KFP17653.1 - 5.2e-20 71.3 0.2 1.1e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Thioredoxin PF00085.20 KFP17654.1 - 3.5e-71 235.7 2.9 4.6e-24 84.4 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.6 KFP17654.1 - 2.2e-26 92.4 4.3 1.2e-07 32.2 0.0 4.2 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP17654.1 - 1.3e-17 63.8 0.1 1.5e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.21 KFP17654.1 - 1.9e-16 60.1 0.5 5.1e-05 23.2 0.0 3.6 3 0 0 3 3 3 3 AhpC/TSA family Thioredoxin_8 PF13905.6 KFP17654.1 - 4.5e-14 52.5 0.5 0.0023 18.2 0.0 5.3 3 2 2 5 5 5 3 Thioredoxin-like OST3_OST6 PF04756.13 KFP17654.1 - 4.9e-13 49.1 0.0 0.00012 21.5 0.0 3.1 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFP17654.1 - 6.2e-12 45.5 1.3 0.012 15.3 0.0 3.4 2 1 1 3 3 3 3 Redoxin Thioredoxin_6 PF13848.6 KFP17654.1 - 3.5e-11 43.4 0.8 0.02 14.8 0.0 4.3 5 0 0 5 5 5 3 Thioredoxin-like domain TraF PF13728.6 KFP17654.1 - 2.5e-08 34.0 0.0 0.19 11.5 0.0 3.5 3 0 0 3 3 3 3 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KFP17654.1 - 8.2e-08 32.1 0.1 0.086 12.6 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin HyaE PF07449.11 KFP17654.1 - 9.5e-05 22.3 0.0 1.4 8.9 0.0 3.7 3 1 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KFP17654.1 - 0.00035 20.6 0.2 0.47 10.5 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KFP17654.1 - 0.072 13.3 6.2 5.8 7.0 0.3 3.5 2 1 1 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 KFP17654.1 - 0.21 11.8 14.8 1.4 9.2 0.2 4.4 4 2 0 4 4 4 0 Glutaredoxin DSBA PF01323.20 KFP17654.1 - 0.67 9.7 4.6 21 4.8 0.2 4.3 3 3 2 5 5 5 0 DSBA-like thioredoxin domain Sema PF01403.19 KFP17655.1 - 2.4e-130 435.2 0.7 4.6e-130 434.2 0.1 1.8 2 0 0 2 2 2 1 Sema domain TSP_1 PF00090.19 KFP17655.1 - 1.4e-43 146.8 94.9 1.4e-10 41.2 9.0 7.7 7 0 0 7 7 7 5 Thrombospondin type 1 domain 7TM_GPCR_Srz PF10325.9 KFP17655.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz MFS_1 PF07690.16 KFP17656.1 - 7.9e-06 25.0 28.9 7.9e-06 25.0 28.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AceK PF06315.11 KFP17656.1 - 0.2 10.1 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Cupin_8 PF13621.6 KFP17657.1 - 1.5e-33 116.6 0.0 2.6e-33 115.8 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP17657.1 - 6.7e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFP17657.1 - 0.003 18.0 0.1 0.0063 16.9 0.1 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Pox_C7_F8A PF03287.14 KFP17657.1 - 0.1 12.6 0.0 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus C7/F8A protein PTR2 PF00854.21 KFP17658.1 - 1.3e-48 165.8 4.9 1.9e-48 165.2 4.9 1.2 1 0 0 1 1 1 1 POT family EAF PF09816.9 KFP17659.1 - 1.7e-14 54.0 0.1 6.2e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor AF-4 PF05110.13 KFP17659.1 - 0.0074 14.4 27.8 0.0098 14.1 27.8 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein PAN_3 PF08277.12 KFP17659.1 - 0.032 14.0 0.1 0.081 12.7 0.1 1.7 1 0 0 1 1 1 0 PAN-like domain Allexi_40kDa PF05549.11 KFP17659.1 - 0.29 10.6 5.2 0.39 10.2 5.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Lin-8 PF03353.15 KFP17659.1 - 0.33 10.5 10.2 0.48 9.9 10.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BBP1_C PF15272.6 KFP17659.1 - 0.35 10.7 6.2 0.53 10.1 6.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Miga PF10265.9 KFP17659.1 - 0.65 8.9 7.8 0.78 8.6 7.8 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 KFP17659.1 - 0.73 8.3 13.2 0.8 8.2 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Cwf_Cwc_15 PF04889.12 KFP17659.1 - 0.84 9.3 12.5 1.4 8.6 12.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 KFP17659.1 - 6.2 6.4 27.1 11 5.5 27.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IQ PF00612.27 KFP17660.1 - 1.1e-14 52.8 20.2 1.1e-06 27.9 0.8 5.3 4 0 0 4 4 4 4 IQ calmodulin-binding motif RhoGEF PF00621.20 KFP17662.1 - 5e-38 131.2 2.9 9.9e-38 130.2 2.9 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFP17662.1 - 0.031 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Sda PF08970.10 KFP17662.1 - 0.095 12.5 1.0 0.23 11.2 1.0 1.7 1 0 0 1 1 1 0 Sporulation inhibitor A MKRN1_C PF15815.5 KFP17662.1 - 0.23 11.9 2.1 4.6 7.7 0.3 2.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal Translin PF01997.16 KFP17663.1 - 2.5e-50 171.3 0.1 2.8e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Translin family hNIFK_binding PF12196.8 KFP17664.1 - 2.8e-19 68.3 0.7 5.6e-19 67.3 0.7 1.5 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK RRM_1 PF00076.22 KFP17664.1 - 3.6e-05 23.5 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Olfactory_mark PF06554.12 KFP17664.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Olfactory marker protein CLASP_N PF12348.8 KFP17665.1 - 8.1e-56 189.1 14.6 3.6e-37 128.1 0.5 4.9 4 1 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 KFP17665.1 - 2.8e-19 67.6 9.1 1.2e-05 25.1 0.0 9.7 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFP17665.1 - 5.3e-12 46.0 2.0 0.016 15.7 0.1 6.1 6 0 0 6 6 5 3 HEAT-like repeat HEAT_2 PF13646.6 KFP17665.1 - 1.4e-10 41.4 4.0 0.1 13.0 0.0 7.8 5 2 4 10 10 10 4 HEAT repeats Sec7_N PF12783.7 KFP17665.1 - 9.8e-08 32.1 7.5 0.017 15.0 0.0 5.3 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 KFP17665.1 - 2.1e-07 31.4 1.6 1.9 9.2 0.0 6.0 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP17665.1 - 2.3e-07 31.0 11.3 0.0046 17.0 0.9 6.4 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFP17665.1 - 4e-06 27.0 9.6 0.061 13.5 0.1 5.8 6 2 1 7 7 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFP17665.1 - 4.7e-05 22.1 9.7 1.2 7.6 0.0 5.7 5 2 0 7 7 7 3 Adaptin N terminal region Tti2 PF10521.9 KFP17665.1 - 0.00013 21.7 4.8 2.4 7.6 0.0 5.4 4 1 0 5 5 5 2 Tti2 family ParcG PF10274.9 KFP17665.1 - 0.00035 20.7 1.6 0.0075 16.4 0.1 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein TFCD_C PF12612.8 KFP17665.1 - 0.0012 18.8 1.6 0.026 14.4 0.2 3.6 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal MMS19_C PF12460.8 KFP17665.1 - 0.002 17.3 1.4 1.6 7.8 0.1 3.4 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 KFP17665.1 - 0.003 16.7 2.9 0.36 9.9 0.1 3.6 4 0 0 4 4 4 1 Dopey, N-terminal MMS19_N PF14500.6 KFP17665.1 - 0.0034 17.0 6.0 0.61 9.6 0.2 4.6 3 2 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 KFP17665.1 - 0.0075 16.4 1.3 0.22 11.7 0.1 3.9 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair XRN_M PF17846.1 KFP17665.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain CTK3 PF12243.8 KFP17665.1 - 0.065 13.2 0.1 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 HMW1C_N PF18071.1 KFP17665.1 - 0.068 13.0 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 HMW1C N-terminal RasGEF_N_2 PF14663.6 KFP17665.1 - 0.085 13.3 0.2 8.2 6.9 0.1 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TPR_20 PF14561.6 KFP17665.1 - 0.097 13.0 3.1 0.35 11.2 0.4 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat CP2 PF04516.15 KFP17666.1 - 5.6e-54 182.9 0.0 8.1e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFP17666.1 - 2.3e-17 62.5 0.0 4.3e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP17666.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain NRIP1_repr_4 PF15690.5 KFP17668.1 - 8.8e-169 560.7 11.1 8.8e-169 560.7 11.1 2.5 2 0 0 2 2 2 1 Nuclear receptor-interacting protein 1 repression 4 NRIP1_repr_1 PF15687.5 KFP17668.1 - 9.5e-141 468.9 19.5 9.5e-141 468.9 19.5 2.7 2 0 0 2 2 2 1 Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 PF15688.5 KFP17668.1 - 4.3e-128 427.8 21.8 4.3e-128 427.8 21.8 3.2 3 2 1 4 4 4 1 Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 PF15689.5 KFP17668.1 - 9.1e-44 147.7 1.1 9.1e-44 147.7 1.1 3.3 2 0 0 2 2 2 1 Nuclear receptor-interacting protein 1 repression 3 V-set PF07686.17 KFP17673.1 - 7.3e-23 80.8 0.4 6.6e-19 68.1 0.0 2.8 2 1 1 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.16 KFP17673.1 - 8.2e-17 61.1 0.0 8.6e-08 32.2 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP17673.1 - 1.2e-15 57.8 0.1 4.7e-08 33.5 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP17673.1 - 2.4e-14 53.4 0.5 1.2e-08 35.1 0.1 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP17673.1 - 8.2e-14 51.6 0.0 9e-06 25.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP17673.1 - 0.00023 21.1 0.0 0.24 11.5 0.0 3.1 3 0 0 3 3 3 1 C17orf99 Ig domain Ig_4 PF16680.5 KFP17673.1 - 0.0007 19.8 0.2 0.26 11.6 0.0 2.9 3 0 0 3 3 2 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP17673.1 - 0.0012 19.2 0.4 0.12 12.8 0.0 3.1 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_CD47 PF08204.11 KFP17673.1 - 0.0015 18.6 0.0 0.56 10.2 0.0 2.5 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_6 PF18452.1 KFP17673.1 - 0.0023 17.5 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain EphA2_TM PF14575.6 KFP17673.1 - 0.015 16.1 0.0 0.029 15.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mucin15 PF15672.5 KFP17673.1 - 0.017 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Syndecan PF01034.20 KFP17673.1 - 0.019 14.9 0.0 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 Syndecan domain FAM163 PF15069.6 KFP17673.1 - 0.021 15.3 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 FAM163 family Adeno_E3_CR2 PF02439.15 KFP17673.1 - 0.03 14.1 1.1 0.068 12.9 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Izumo-Ig PF16706.5 KFP17673.1 - 0.036 14.1 0.0 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Tweety PF04906.13 KFP17673.1 - 0.083 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Tweety Cadherin_C_2 PF16492.5 KFP17673.1 - 0.097 13.4 0.0 0.3 11.9 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal LST1 PF05083.13 KFP17673.1 - 0.1 12.9 0.1 20 5.6 0.0 2.5 2 0 0 2 2 2 0 LST-1 protein C2-set PF05790.15 KFP17673.1 - 0.17 12.1 0.9 2.1 8.6 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin C2-set domain EURL PF06937.11 KFP17674.1 - 9.7e-151 501.0 5.0 1.1e-150 500.8 5.0 1.0 1 0 0 1 1 1 1 EURL protein XRCC4 PF06632.12 KFP17674.1 - 0.014 14.2 0.5 0.025 13.5 0.5 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 HSBP1 PF06825.12 KFP17674.1 - 0.13 12.2 1.5 0.23 11.3 1.5 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Lectin_C PF00059.21 KFP17675.1 - 3.3e-13 50.3 0.1 7e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Lectin C-type domain DUF3377 PF11857.8 KFP17675.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF1708 PF08101.11 KFP17678.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) TLV_coat PF00429.19 KFP17680.1 - 0.00099 17.9 0.3 0.00099 17.9 0.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Cpn10 PF00166.21 KFP17683.1 - 1.2e-17 63.7 0.6 1.3e-17 63.6 0.6 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit I-set PF07679.16 KFP17685.1 - 8.7e-83 272.5 0.6 1.6e-19 69.8 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP17685.1 - 4e-68 226.0 6.9 3e-17 63.0 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP17685.1 - 3.4e-49 165.0 0.7 2.6e-10 40.3 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFP17685.1 - 3.4e-46 155.5 0.6 7.9e-10 39.0 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFP17685.1 - 3.2e-30 104.3 2.3 5.1e-17 62.0 0.7 2.8 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KFP17685.1 - 1.8e-27 95.7 2.1 1.2e-05 25.4 0.0 8.2 4 3 1 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP17685.1 - 2.2e-12 46.9 1.2 0.0011 18.9 0.0 5.2 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP17685.1 - 1e-11 44.7 0.1 0.016 15.3 0.0 4.9 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP17685.1 - 1.9e-11 43.8 0.0 0.1 12.7 0.0 5.5 5 0 0 5 5 5 3 C17orf99 Ig domain Ig_5 PF16681.5 KFP17685.1 - 1.3e-09 38.3 0.2 0.092 13.2 0.0 5.1 5 0 0 5 5 5 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP17685.1 - 7.7e-09 35.7 0.9 0.65 10.3 0.0 6.0 5 1 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP17685.1 - 7.7e-09 35.0 0.0 1.2 8.8 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP17685.1 - 1e-06 28.9 0.5 3 8.1 0.0 5.3 5 1 0 5 5 5 1 Natural killer cell receptor 2B4 Adeno_E3_CR1 PF02440.15 KFP17685.1 - 1.6e-06 27.8 0.0 0.32 10.8 0.0 3.9 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 Herpes_gE PF02480.16 KFP17685.1 - 0.00018 20.4 0.1 0.27 9.9 0.1 3.4 1 1 2 3 3 3 1 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 KFP17685.1 - 0.00041 20.9 2.0 0.0024 18.4 0.9 2.9 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP17685.1 - 0.0058 16.9 0.0 2 8.8 0.0 3.0 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III C2-set PF05790.15 KFP17685.1 - 0.084 13.1 0.5 9.1 6.5 0.0 4.2 5 0 0 5 5 4 0 Immunoglobulin C2-set domain TGS PF02824.21 KFP17697.1 - 0.00061 19.8 0.0 0.0023 18.0 0.0 2.0 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KFP17697.1 - 0.001 19.1 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF2469 PF10611.9 KFP17697.1 - 0.0029 18.1 0.1 0.011 16.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2469) Ig_3 PF13927.6 KFP17698.1 - 1.9e-20 73.2 1.0 6.3e-14 52.3 0.5 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP17698.1 - 2.3e-17 62.9 0.6 5.4e-09 36.1 0.3 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP17698.1 - 2.3e-16 59.6 0.2 7.7e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP17698.1 - 2e-15 56.9 0.9 7.4e-07 29.3 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP17698.1 - 7.8e-14 51.8 1.1 9.1e-10 38.7 0.5 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFP17698.1 - 3.2e-06 26.6 0.0 0.0018 17.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP17698.1 - 1.4e-05 25.0 0.0 0.00016 21.6 0.0 2.4 2 1 0 2 2 2 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP17698.1 - 0.00017 21.6 0.4 0.06 13.4 0.1 2.6 2 1 0 2 2 2 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP17698.1 - 0.0012 19.1 1.4 8 6.8 0.2 3.6 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP17698.1 - 0.0078 16.3 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP17698.1 - 0.018 15.5 0.7 1.2 9.6 0.2 3.1 3 1 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Receptor_2B4 PF11465.8 KFP17698.1 - 0.019 15.2 0.1 6.6 7.0 0.0 2.8 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 DUF4307 PF14155.6 KFP17698.1 - 0.34 10.8 4.9 0.68 9.8 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) FixS PF03597.15 KFP17698.1 - 0.78 9.5 2.5 2 8.2 2.5 1.7 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type ATP-synt_F6 PF05511.11 KFP17699.1 - 2.7e-45 152.8 0.1 3e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Ets PF00178.22 KFP17700.1 - 9.4e-34 115.7 0.3 2.1e-33 114.6 0.3 1.6 1 0 0 1 1 1 1 Ets-domain GABP-alpha PF11620.8 KFP17700.1 - 6.8e-32 109.5 0.8 1.4e-31 108.6 0.8 1.5 1 0 0 1 1 1 1 GA-binding protein alpha chain SAM_PNT PF02198.16 KFP17700.1 - 3e-28 97.6 0.1 8.9e-28 96.1 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Syntaxin-18_N PF10496.9 KFP17700.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus APP_E2 PF12925.7 KFP17702.1 - 2.6e-73 245.8 19.9 4.6e-73 245.0 19.9 1.4 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 KFP17702.1 - 1.3e-44 150.6 0.5 1.3e-44 150.6 0.5 2.4 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding APP_Cu_bd PF12924.7 KFP17702.1 - 2.3e-26 92.3 4.9 2.3e-26 92.3 4.9 2.4 3 0 0 3 3 2 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 KFP17702.1 - 1.2e-25 89.8 0.3 5.2e-25 87.7 0.3 2.2 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus Beta-APP PF03494.13 KFP17702.1 - 1.9e-23 82.0 1.0 3.4e-23 81.2 1.0 1.4 1 0 0 1 1 1 1 Beta-amyloid peptide (beta-APP) Kunitz_BPTI PF00014.23 KFP17702.1 - 1.9e-19 69.7 6.2 3.8e-19 68.7 6.2 1.6 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Insulin_TMD PF17870.1 KFP17702.1 - 0.27 11.3 2.7 0.33 11.1 1.0 1.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PilJ PF13675.6 KFP17702.1 - 1.9 8.6 5.9 1.7 8.7 3.2 2.3 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RNase_H2-Ydr279 PF09468.10 KFP17702.1 - 2 8.6 7.1 0.18 12.0 1.8 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Bcl-2 PF00452.19 KFP17702.1 - 2.1 9.1 4.2 5.6 7.7 0.1 3.2 2 1 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Syndecan PF01034.20 KFP17702.1 - 3.1 7.8 4.0 9 6.3 2.1 2.3 2 0 0 2 2 2 0 Syndecan domain Activator-TraM PF11657.8 KFP17702.1 - 4.2 7.2 11.1 0.49 10.2 5.9 2.0 2 0 0 2 2 2 0 Transcriptional activator TraM CYYR1 PF10873.8 KFP17703.1 - 1.1e-49 168.7 16.5 1.2e-49 168.6 16.5 1.0 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 KFP17703.1 - 1.4 9.0 5.4 1.9 8.5 5.4 1.2 1 0 0 1 1 1 0 Podoplanin ADAM_spacer1 PF05986.14 KFP17705.1 - 4.9e-32 110.3 0.0 8.2e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFP17705.1 - 1e-25 90.0 24.4 1.1e-22 80.3 9.7 4.2 3 1 0 3 3 3 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP17705.1 - 9.2e-20 71.4 0.0 1.5e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFP17705.1 - 3.5e-15 55.9 49.4 1.8e-08 34.4 6.5 6.1 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 KFP17705.1 - 1.1e-12 48.5 0.2 2.2e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP17705.1 - 4.1e-11 43.5 0.0 7.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP17705.1 - 0.0004 20.1 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP17705.1 - 0.00045 20.2 0.1 0.0009 19.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CxC6 PF18721.1 KFP17705.1 - 0.011 16.0 3.0 0.011 16.0 3.0 3.7 4 0 0 4 4 4 0 CxC6 like cysteine cluster associated with KDZ transposases Atracotoxin PF05353.11 KFP17706.1 - 0.032 14.3 9.5 0.059 13.4 9.5 1.6 1 0 0 1 1 1 0 Delta Atracotoxin ADAM_spacer1 PF05986.14 KFP17707.1 - 1.4e-33 115.4 0.1 2.1e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 KFP17707.1 - 2.1e-22 80.0 0.1 4e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP17707.1 - 3.6e-22 78.6 14.4 1.5e-20 73.5 5.9 5.2 6 0 0 6 6 5 2 ADAM cysteine-rich domain Reprolysin_3 PF13582.6 KFP17707.1 - 1.1e-12 48.6 0.9 2.8e-12 47.2 0.9 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP17707.1 - 1.9e-12 47.7 0.8 4.1e-12 46.7 0.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.19 KFP17707.1 - 4.4e-10 39.6 5.5 4.4e-10 39.6 5.5 4.3 4 0 0 4 4 3 2 Thrombospondin type 1 domain Reprolysin_2 PF13574.6 KFP17707.1 - 2.1e-06 27.8 0.4 5.6e-06 26.4 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP17707.1 - 7e-06 25.8 0.4 1.4e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP17707.1 - 0.0013 18.5 0.4 0.0029 17.5 0.4 1.6 1 0 0 1 1 1 1 Matrixin CxC6 PF18721.1 KFP17707.1 - 0.0089 16.3 3.8 0.0089 16.3 3.8 3.3 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Astacin PF01400.24 KFP17707.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3285 PF11688.8 KFP17707.1 - 0.026 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) DUF4953 PF16313.5 KFP17707.1 - 0.061 12.5 0.5 0.13 11.5 0.5 1.4 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 KFP17707.1 - 0.088 12.8 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 GON PF08685.11 KFP17711.1 - 0.23 11.3 0.0 0.24 11.2 0.0 1.0 1 0 0 1 1 1 0 GON domain MTS PF05175.14 KFP17713.1 - 3.6e-08 33.1 0.0 6.8e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KFP17713.1 - 0.00014 21.4 0.0 0.00094 18.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFP17713.1 - 0.0012 19.5 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP17713.1 - 0.0058 16.4 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFP17713.1 - 0.0073 17.3 0.0 0.013 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFP17713.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 KFP17713.1 - 0.035 14.9 0.0 0.078 13.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DUF1115 PF06544.12 KFP17714.1 - 4.5e-18 65.7 0.1 2.3e-17 63.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 KFP17714.1 - 1.5e-15 57.4 0.6 2.8e-15 56.6 0.6 1.4 1 0 0 1 1 1 1 RWD domain UCH PF00443.29 KFP17715.1 - 3e-53 180.9 1.7 7.7e-53 179.6 1.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP17715.1 - 1.2e-15 57.5 1.9 1.2e-15 57.5 1.9 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein MMR_HSR1 PF01926.23 KFP17715.1 - 0.0011 19.1 0.8 0.011 15.8 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase zinc_ribbon_10 PF10058.9 KFP17715.1 - 0.84 9.4 4.3 1 9.2 0.4 2.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4050 PF13259.6 KFP17715.1 - 6.9 6.9 15.2 15 5.8 9.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Cpn60_TCP1 PF00118.24 KFP17716.1 - 3.8e-154 513.9 7.6 4.3e-154 513.8 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family APG6_N PF17675.1 KFP17717.1 - 0.0013 19.2 10.1 0.0013 19.2 10.1 1.4 2 0 0 2 2 1 1 Apg6 coiled-coil region FTA4 PF13093.6 KFP17717.1 - 0.027 14.4 4.2 0.029 14.2 4.2 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 KFP17717.1 - 0.043 13.2 13.8 0.058 12.7 13.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KFP17717.1 - 0.11 12.4 3.3 0.22 11.4 3.3 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 KFP17717.1 - 0.19 12.1 13.2 4.8 7.6 13.3 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Spc24 PF08286.11 KFP17717.1 - 0.23 11.7 10.5 4.2 7.7 10.5 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 KFP17717.1 - 0.24 11.8 11.6 0.46 10.9 11.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 SLATT_5 PF18160.1 KFP17717.1 - 0.36 10.1 4.8 0.51 9.6 4.8 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DASH_Spc19 PF08287.11 KFP17717.1 - 0.37 10.7 10.2 0.56 10.1 10.2 1.3 1 0 0 1 1 1 0 Spc19 Takusan PF04822.13 KFP17717.1 - 0.85 9.5 8.7 1.5 8.7 8.7 1.5 1 0 0 1 1 1 0 Takusan Seryl_tRNA_N PF02403.22 KFP17717.1 - 2.5 8.3 10.1 4.3 7.6 10.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 KFP17717.1 - 3.2 7.9 14.6 2.6 8.2 2.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 KFP17717.1 - 3.7 8.1 17.3 14 6.2 9.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 KFP17717.1 - 4.7 7.3 15.2 11 6.1 15.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KFP17717.1 - 4.9 7.8 9.9 2.9 8.6 4.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KFP17717.1 - 7.6 6.7 14.1 1.4 9.1 2.5 2.6 2 1 1 3 3 3 0 bZIP transcription factor ANF_receptor PF01094.28 KFP17718.1 - 5.7e-74 249.3 0.0 7.9e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP17718.1 - 7.3e-54 181.7 0.1 1.2e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP17718.1 - 1.2e-46 157.6 0.0 4.6e-46 155.7 0.0 2.0 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP17718.1 - 2.3e-19 69.8 0.0 5.4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP17718.1 - 1.8e-06 27.9 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Tiam_CC_Ex PF18385.1 KFP17719.1 - 2.9e-57 191.1 0.2 6.9e-57 189.9 0.2 1.7 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain RhoGEF PF00621.20 KFP17719.1 - 4.9e-36 124.7 1.5 4.9e-36 124.7 1.5 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP17719.1 - 5.9e-27 94.2 2.7 7.3e-15 55.4 0.4 3.4 3 0 0 3 3 3 2 PH domain RBD PF02196.15 KFP17719.1 - 9.4e-17 60.9 0.0 2.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain PH_9 PF15410.6 KFP17719.1 - 6.9e-11 42.6 0.3 1.9e-10 41.1 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ PF00595.24 KFP17719.1 - 4.8e-07 30.0 0.0 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP17719.1 - 0.00048 19.9 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP17719.1 - 0.00054 20.2 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 KFP17719.1 - 0.00093 19.6 0.3 0.0089 16.4 0.4 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain AAA_22 PF13401.6 KFP17719.1 - 0.063 13.6 1.4 16 5.8 0.1 3.7 4 0 0 4 4 4 0 AAA domain GNAT_acetyltran PF12746.7 KFP17719.1 - 0.21 11.1 0.9 0.41 10.2 0.9 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase NBP1 PF08537.10 KFP17719.1 - 2.7 7.3 10.2 1.3 8.4 0.7 2.9 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 Sod_Cu PF00080.20 KFP17720.1 - 1.3e-43 148.5 4.6 1.5e-43 148.3 4.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTD_bind PF04818.13 KFP17721.1 - 1.8e-17 63.9 0.0 6.1e-17 62.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KFP17721.1 - 5e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP17721.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 KFP17722.1 - 7.6e-64 215.6 0.0 1.1e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17722.1 - 6.7e-35 120.6 0.0 9.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP17722.1 - 3.6e-12 46.2 0.0 5.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP17722.1 - 1.4e-06 27.8 0.2 2.9e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP17722.1 - 5.9e-05 22.7 0.8 0.00017 21.3 0.4 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KFP17722.1 - 9.4e-05 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP17722.1 - 0.0033 16.4 0.2 0.007 15.3 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP17722.1 - 0.027 13.2 0.0 0.048 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase tRNA_bind_2 PF13725.6 KFP17722.1 - 0.031 14.0 1.0 0.21 11.3 0.2 2.2 2 0 0 2 2 2 0 Possible tRNA binding domain Npa1 PF11707.8 KFP17724.1 - 9.7e-91 304.6 8.0 5.6e-89 298.8 0.3 4.1 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KFP17724.1 - 4.8e-59 199.3 0.7 4.8e-59 199.3 0.7 4.3 3 1 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 DUF4756 PF15948.5 KFP17724.1 - 0.82 9.5 9.9 0.16 11.8 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4756) FAM176 PF14851.6 KFP17725.1 - 3.3e-54 182.5 0.4 4.9e-54 181.9 0.4 1.3 1 0 0 1 1 1 1 FAM176 family Gal_Lectin PF02140.18 KFP17725.1 - 1.8e-30 105.2 8.6 4.5e-18 65.5 1.5 2.4 2 0 0 2 2 2 2 Galactose binding lectin domain VIT1 PF01988.19 KFP17725.1 - 0.033 14.0 1.5 0.074 12.9 0.8 1.8 2 0 0 2 2 2 0 VIT family Pes-10 PF07149.11 KFP17725.1 - 1.1 8.2 7.4 1.7 7.7 7.4 1.1 1 0 0 1 1 1 0 Pes-10 DUF2870 PF11069.8 KFP17726.1 - 1.7e-45 153.3 2.0 1.7e-45 153.3 2.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 KFP17726.1 - 0.041 13.6 2.8 0.18 11.6 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin family GCFC PF07842.12 KFP17727.1 - 8.8e-34 117.4 0.6 8.8e-34 117.4 0.6 1.9 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein BLOC1_2 PF10046.9 KFP17727.1 - 0.13 12.6 3.3 1.7 9.0 1.1 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4571 PF15137.6 KFP17728.1 - 2.5e-105 351.0 5.0 2.8e-105 350.8 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) Interfer-bind PF09294.10 KFP17729.1 - 6.4e-20 71.4 0.2 8e-20 71.1 0.2 1.1 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III T4_baseplate PF12322.8 KFP17729.1 - 0.0029 17.1 0.3 0.0045 16.5 0.2 1.4 1 1 0 1 1 1 1 T4 bacteriophage base plate protein Pro_dh PF01619.18 KFP17729.1 - 0.052 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Proline dehydrogenase fn3 PF00041.21 KFP17729.1 - 0.11 12.8 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Fibronectin type III domain Interfer-bind PF09294.10 KFP17731.1 - 1.6e-27 95.9 0.2 2.7e-27 95.1 0.0 1.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP17731.1 - 0.00023 21.5 0.0 0.00055 20.2 0.0 1.6 2 0 0 2 2 2 1 Fibronectin type III domain Interfer-bind PF09294.10 KFP17732.1 - 2.5e-45 153.0 1.0 1e-21 77.2 0.0 3.1 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFP17732.1 - 2.4e-29 101.3 13.7 1.5e-14 53.7 0.5 3.5 4 0 0 4 4 4 2 Tissue factor fn3 PF00041.21 KFP17732.1 - 2.5e-06 27.7 9.3 9.5e-05 22.7 0.1 4.3 4 1 0 4 4 4 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP17732.1 - 0.0027 18.3 2.7 3.5 8.3 0.0 3.7 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KFP17733.1 - 1e-20 73.6 1.5 3.1e-20 72.0 0.8 2.0 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.10 KFP17733.1 - 3.3e-17 62.7 0.1 5.6e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP17733.1 - 3.6e-08 33.6 1.4 1.3e-07 31.8 0.1 2.2 2 1 0 2 2 2 1 Fibronectin type III domain UPF0220 PF05255.11 KFP17734.1 - 2.2e-51 173.7 4.6 2.5e-51 173.5 4.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1218 PF06749.12 KFP17734.1 - 6.3 7.4 7.8 1.2 9.7 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF1992 PF09350.10 KFP17735.1 - 8e-23 80.4 0.1 1.9e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.31 KFP17735.1 - 1.1e-15 57.5 0.3 3.6e-15 55.8 0.1 2.1 1 1 0 1 1 1 1 DnaJ domain DUF3597 PF12200.8 KFP17735.1 - 0.0094 16.5 0.2 0.018 15.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) G-patch PF01585.23 KFP17736.1 - 2.3e-17 62.6 3.0 5.2e-17 61.5 3.0 1.6 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.26 KFP17736.1 - 1.7e-14 54.3 0.0 5.1e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP17736.1 - 3.1e-12 46.6 0.0 1.1e-11 44.8 0.0 2.0 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 G-patch_2 PF12656.7 KFP17736.1 - 2.6e-07 30.6 1.0 8.4e-07 29.0 1.0 1.9 1 0 0 1 1 1 1 G-patch domain RSRP PF17069.5 KFP17736.1 - 0.00024 20.8 0.7 0.00046 19.8 0.7 1.4 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 ADH_zinc_N PF00107.26 KFP17738.1 - 6e-07 29.5 0.0 9.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP17738.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.4 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFP17738.1 - 0.14 13.2 0.0 0.41 11.7 0.0 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PH_13 PF16652.5 KFP17739.1 - 7.8e-74 246.7 0.1 7.8e-74 246.7 0.1 4.0 3 1 1 4 4 2 1 Pleckstrin homology domain SH3_9 PF14604.6 KFP17739.1 - 1.3e-68 226.6 6.7 2.8e-16 59.1 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFP17739.1 - 1.1e-63 210.6 14.1 1.1e-16 60.1 0.3 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFP17739.1 - 3e-57 190.1 1.5 4.8e-14 51.8 0.0 5.6 5 0 0 5 5 5 5 Variant SH3 domain INTAP PF16617.5 KFP17739.1 - 1e-56 190.2 14.0 1e-56 190.2 14.0 2.2 2 0 0 2 2 2 1 Intersectin and clathrin adaptor AP2 binding region RhoGEF PF00621.20 KFP17739.1 - 5.7e-46 157.0 2.0 5.7e-46 157.0 2.0 3.2 3 1 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.7 KFP17739.1 - 6.6e-31 106.3 0.0 9.7e-15 54.4 0.0 3.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 KFP17739.1 - 2.4e-21 76.0 0.0 6.4e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KFP17739.1 - 8e-09 34.4 0.0 0.0029 17.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP17739.1 - 6.3e-07 28.8 0.2 0.39 10.8 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KFP17739.1 - 4e-06 27.2 0.0 0.0059 17.0 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair PH PF00169.29 KFP17739.1 - 0.00079 19.9 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 KFP17739.1 - 0.0034 16.8 0.2 0.63 9.6 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP17739.1 - 0.065 13.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair GSH_synthase PF03199.15 KFP17739.1 - 0.072 13.5 1.6 0.39 11.2 0.2 3.1 2 1 0 2 2 2 0 Eukaryotic glutathione synthase OSCP PF00213.18 KFP17740.1 - 3.3e-36 125.0 0.1 3.6e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit SIKE PF05769.11 KFP17740.1 - 0.06 13.3 0.0 0.091 12.7 0.0 1.4 1 1 0 1 1 1 0 SIKE family SSF PF00474.17 KFP17741.1 - 2.1e-162 540.6 22.7 2.8e-162 540.2 22.7 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Ribosomal_S6 PF01250.17 KFP17742.1 - 8.6e-15 54.8 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 ISK_Channel PF02060.15 KFP17743.1 - 1.8e-17 63.2 0.3 2.1e-17 63.0 0.3 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel COX2_TM PF02790.15 KFP17743.1 - 0.015 15.4 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain FAM165 PF14981.6 KFP17744.1 - 9.1e-31 105.4 4.2 9.6e-31 105.4 4.2 1.0 1 0 0 1 1 1 1 FAM165 family MadM PF03818.13 KFP17744.1 - 0.0071 16.2 0.0 0.008 16.0 0.0 1.1 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit ISK_Channel PF02060.15 KFP17747.1 - 4.2e-58 194.4 0.0 4.7e-58 194.2 0.0 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel GST_C_2 PF13410.6 KFP17748.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP17748.1 - 2.9e-05 24.3 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP17748.1 - 6.1e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP17748.1 - 0.0011 19.2 0.3 0.0056 16.9 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EST1_DNA_bind PF10373.9 KFP17748.1 - 0.025 14.1 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain GST_C_3 PF14497.6 KFP17748.1 - 0.034 14.3 0.2 0.099 12.8 0.1 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Runt PF00853.19 KFP17750.1 - 2.2e-53 179.2 0.3 3.2e-53 178.7 0.3 1.2 1 0 0 1 1 1 1 Runt domain RunxI PF08504.11 KFP17750.1 - 9.7e-43 144.9 4.7 2.1e-42 143.8 4.7 1.6 1 0 0 1 1 1 1 Runx inhibition domain DUF3037 PF11236.8 KFP17750.1 - 0.045 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) SET PF00856.28 KFP17753.1 - 1.1e-13 51.9 0.0 2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KFP17753.1 - 4.5e-11 43.6 0.7 7.5e-11 42.8 0.7 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Dna2 PF08696.11 KFP17753.1 - 0.071 12.9 0.6 0.16 11.8 0.6 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 adh_short PF00106.25 KFP17754.1 - 4.3e-35 121.0 0.0 5.8e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFP17754.1 - 2.1e-26 92.9 0.0 4.3e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP17754.1 - 2.8e-07 30.6 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFP17754.1 - 0.00074 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein HATPase_c PF02518.26 KFP17754.1 - 0.0022 18.5 0.0 0.03 14.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dopey_N PF04118.14 KFP17755.1 - 8e-98 327.3 2.5 2.9e-97 325.5 2.5 2.1 1 0 0 1 1 1 1 Dopey, N-terminal Lin-8 PF03353.15 KFP17755.1 - 0.06 12.9 9.4 0.14 11.7 9.4 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Phage_holin_4_1 PF05105.12 KFP17755.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin family CAF-1_p60_C PF15512.6 KFP17756.1 - 1.9e-62 210.9 26.9 2.6e-62 210.5 26.9 1.2 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.32 KFP17756.1 - 4.2e-23 81.2 13.3 1.4e-06 28.9 0.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17756.1 - 2.6e-14 53.3 0.2 0.0038 17.5 0.3 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP17756.1 - 1.4e-05 25.0 0.9 0.0016 18.3 0.1 3.5 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFP17756.1 - 2.3e-05 23.7 0.1 0.0091 15.1 0.0 2.6 1 1 1 2 2 2 2 Coatomer WD associated region IKI3 PF04762.12 KFP17756.1 - 0.0012 17.0 0.3 0.077 11.0 0.0 2.2 2 0 0 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 KFP17756.1 - 0.0036 16.3 0.3 0.34 9.8 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFP17756.1 - 0.085 11.5 1.1 1.7 7.2 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 KFP17756.1 - 2 8.5 7.1 7.7 6.6 1.2 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PMP22_Claudin PF00822.20 KFP17757.1 - 2.2e-33 115.5 11.1 2.8e-33 115.1 11.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP17757.1 - 5.8e-08 32.7 15.1 5.2e-07 29.6 15.1 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP17757.1 - 0.11 12.3 11.7 0.19 11.6 11.2 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF872 PF05915.12 KFP17757.1 - 0.35 11.1 3.0 0.55 10.4 0.9 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SIM_C PF06621.12 KFP17758.1 - 2.7e-65 221.3 9.1 3.6e-65 220.9 9.1 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.12 KFP17758.1 - 1.8e-24 85.8 0.7 9.7e-19 67.5 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP17758.1 - 2.9e-19 69.2 0.3 8.2e-14 51.7 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFP17758.1 - 9.7e-17 61.0 0.0 2.9e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP17758.1 - 0.00012 21.9 0.6 0.00027 20.9 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP17758.1 - 0.00026 21.2 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KFP17758.1 - 0.0058 16.9 0.0 0.099 12.9 0.0 2.3 2 0 0 2 2 2 1 PAS fold BPL_LplA_LipB PF03099.19 KFP17759.1 - 3.3e-24 85.3 0.0 4.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KFP17759.1 - 1.9e-10 40.4 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_N PF09825.9 KFP17760.1 - 8.6e-16 58.0 0.0 7.6e-08 31.8 0.0 2.2 1 1 1 2 2 2 2 Biotin-protein ligase, N terminal ABC_transp_aux PF09822.9 KFP17760.1 - 3.3e-05 23.5 0.2 0.00012 21.6 0.0 1.9 1 1 0 2 2 2 1 ABC-type uncharacterized transport system Ripply PF14998.6 KFP17761.1 - 5.9e-23 81.3 0.0 6.1e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Transcription Regulator PIG-P PF08510.12 KFP17762.1 - 2.8e-39 133.8 1.7 3.2e-39 133.6 1.7 1.0 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KFP17762.1 - 0.018 15.1 1.1 0.024 14.7 1.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AgrB PF04647.15 KFP17762.1 - 0.066 12.5 4.4 2.5 7.4 0.1 2.0 1 1 1 2 2 2 0 Accessory gene regulator B DPM2 PF07297.12 KFP17762.1 - 0.82 10.0 11.3 2.7 8.3 11.3 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4462 PF14692.6 KFP17763.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) TPR_1 PF00515.28 KFP17764.1 - 2.6e-11 42.8 10.3 0.0003 20.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-RING_2 PF13639.6 KFP17764.1 - 4.1e-10 39.8 14.3 4.1e-10 39.8 14.3 3.2 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP17764.1 - 8.4e-08 31.9 12.7 8.4e-08 31.9 12.7 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 KFP17764.1 - 3.6e-07 29.7 0.8 3e-05 23.6 0.0 3.7 3 0 0 3 3 3 1 TPR repeat zf-rbx1 PF12678.7 KFP17764.1 - 5e-07 29.9 11.1 5e-07 29.9 11.1 3.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFP17764.1 - 6.3e-06 26.0 13.3 6.3e-06 26.0 13.3 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KFP17764.1 - 3.5e-05 23.6 15.1 0.76 10.0 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP17764.1 - 8e-05 22.9 7.2 0.072 13.4 0.0 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP17764.1 - 0.00026 21.6 0.2 2.7 8.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KFP17764.1 - 0.00054 19.8 9.9 0.00054 19.8 9.9 3.4 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP17764.1 - 0.0019 18.2 4.9 0.0019 18.2 4.9 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger CARD PF00619.21 KFP17764.1 - 0.002 18.1 0.3 0.008 16.2 0.3 2.1 1 0 0 1 1 1 1 Caspase recruitment domain zf-RING_5 PF14634.6 KFP17764.1 - 0.0042 17.0 11.7 0.0042 17.0 11.7 3.4 4 0 0 4 4 4 1 zinc-RING finger domain TPR_17 PF13431.6 KFP17764.1 - 0.0049 17.2 1.3 0.046 14.1 0.2 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP17764.1 - 0.038 14.2 4.1 0.65 10.4 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 KFP17764.1 - 0.06 13.1 10.9 0.22 11.3 10.9 2.0 1 0 0 1 1 1 0 RING-like zinc finger TPR_14 PF13428.6 KFP17764.1 - 0.062 14.2 1.6 6.1 8.0 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP17764.1 - 0.069 13.4 2.4 0.3 11.3 0.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PAM2 PF07145.15 KFP17764.1 - 0.096 12.4 0.1 0.33 10.7 0.1 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-RING_UBOX PF13445.6 KFP17764.1 - 0.11 12.6 16.7 0.026 14.6 12.4 2.4 2 0 0 2 2 1 0 RING-type zinc-finger YjbH PF06082.11 KFP17764.1 - 0.39 9.5 6.0 0.64 8.8 6.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH zf-Nse PF11789.8 KFP17764.1 - 0.59 10.0 5.8 1.8 8.5 5.8 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 KFP17764.1 - 0.6 10.5 23.7 27 5.2 13.4 4.4 3 0 0 3 3 3 0 RING-like domain Prok-RING_4 PF14447.6 KFP17764.1 - 1.4 8.8 10.9 8.1 6.4 10.8 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_19 PF14559.6 KFP17764.1 - 1.4 9.4 6.5 2 9.0 0.0 4.1 4 2 2 6 6 3 0 Tetratricopeptide repeat HAGH_C PF16123.5 KFP17764.1 - 5.7 7.5 7.3 0.86 10.2 2.0 2.4 2 0 0 2 2 1 0 Hydroxyacylglutathione hydrolase C-terminus Vps26 PF03643.15 KFP17765.1 - 2.1e-68 230.3 0.1 2.4e-68 230.1 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFP17765.1 - 0.0002 21.5 0.3 0.0016 18.5 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 KFP17767.1 - 6.7e-50 169.9 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17767.1 - 5.3e-22 78.3 0.0 9.5e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Filament_head PF04732.14 KFP17767.1 - 0.49 11.3 26.2 0.44 11.4 8.0 2.6 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region IRK_C PF17655.1 KFP17768.1 - 1.3e-72 243.0 0.0 1.9e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP17768.1 - 4.1e-58 195.2 3.5 6.1e-58 194.7 3.5 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP17768.1 - 0.19 11.7 10.9 0.73 9.8 10.9 2.0 1 1 0 1 1 1 0 Ion channel Ets PF00178.22 KFP17771.1 - 2e-36 124.3 0.4 3.8e-36 123.4 0.4 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP17771.1 - 2.1e-26 91.7 0.0 4.3e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 KFP17771.1 - 0.0076 16.3 0.1 0.081 13.0 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KFP17771.1 - 0.018 14.8 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP17771.1 - 0.081 13.4 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PAC1 PF16094.5 KFP17774.1 - 6.5e-65 219.1 3.9 7.2e-65 219.0 3.9 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 CHD5 PF04420.14 KFP17775.1 - 1.1e-36 126.1 0.8 1.2e-36 126.0 0.8 1.0 1 0 0 1 1 1 1 CHD5-like protein DUF1043 PF06295.12 KFP17775.1 - 0.0024 17.9 1.1 0.003 17.6 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF2203 PF09969.9 KFP17775.1 - 0.0049 17.6 1.4 0.2 12.4 0.5 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2203) Lectin_N PF03954.14 KFP17775.1 - 0.089 12.5 0.8 0.14 11.9 0.8 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MCU PF04678.13 KFP17775.1 - 0.11 12.6 5.7 0.77 9.8 5.7 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF1640 PF07798.11 KFP17775.1 - 0.28 11.2 7.1 0.55 10.3 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) MatP_C PF17414.2 KFP17775.1 - 0.69 10.1 4.1 1.8 8.8 1.0 2.2 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Lebercilin PF15619.6 KFP17776.1 - 1.4e-62 210.8 35.8 1.4e-62 210.8 35.8 2.5 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.18 KFP17776.1 - 0.039 14.3 0.9 0.039 14.3 0.9 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family SH3BGR PF04908.15 KFP17777.1 - 1.8e-47 159.5 0.1 2e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KFP17777.1 - 0.00044 20.4 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Ig_3 PF13927.6 KFP17779.1 - 4.4e-14 52.8 1.2 1.1e-06 29.1 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP17779.1 - 4.6e-13 49.1 0.1 7e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP17779.1 - 2e-09 37.5 1.6 0.00049 20.2 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP17779.1 - 1.3e-08 35.1 0.7 8.6e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP17779.1 - 5.7e-08 32.7 1.1 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.15 KFP17779.1 - 0.002 18.3 0.2 0.75 10.0 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin C2-set domain TMEM154 PF15102.6 KFP17779.1 - 0.0025 17.7 0.9 0.0025 17.7 0.9 1.8 2 0 0 2 2 2 1 TMEM154 protein family Protocadherin PF08374.11 KFP17779.1 - 0.0057 16.7 0.6 0.0099 15.9 0.6 1.3 1 0 0 1 1 1 1 Protocadherin Baculo_F PF12259.8 KFP17779.1 - 0.0085 14.7 0.7 0.011 14.4 0.7 1.2 1 0 0 1 1 1 1 Baculovirus F protein Shisa PF13908.6 KFP17779.1 - 0.0088 16.3 1.4 0.017 15.4 1.4 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator C1-set PF07654.15 KFP17779.1 - 0.0092 16.3 0.1 0.21 12.0 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Orthoreo_P10 PF07204.11 KFP17779.1 - 0.034 14.1 0.2 0.078 12.9 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 HPIH PF13323.6 KFP17779.1 - 0.037 13.9 0.3 0.056 13.3 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain with HPIH motif UPF0139 PF03669.13 KFP17779.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) BPA_C PF18040.1 KFP17779.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 beta porphyranase A C-terminal Baculo_11_kDa PF06143.11 KFP17779.1 - 0.086 12.4 1.3 0.21 11.2 1.3 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Collectrin PF16959.5 KFP17779.1 - 0.097 12.4 5.5 0.17 11.6 4.9 1.6 1 1 0 1 1 1 0 Renal amino acid transporter LRR19-TM PF15176.6 KFP17779.1 - 0.17 11.9 0.4 0.45 10.5 0.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Cadherin_C_2 PF16492.5 KFP17779.1 - 0.21 12.3 2.3 0.79 10.5 2.3 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TMEM52 PF14979.6 KFP17779.1 - 0.26 11.2 4.7 0.37 10.7 4.1 1.5 1 1 0 1 1 1 0 Transmembrane 52 DUF872 PF05915.12 KFP17779.1 - 0.26 11.5 2.9 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3827 PF12877.7 KFP17779.1 - 0.57 8.5 3.3 0.79 8.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 KFP17779.1 - 1.1 10.2 2.9 2.5 9.0 2.9 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4389 PF14333.6 KFP17779.1 - 2.3 8.2 9.8 38 4.3 7.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF2207 PF09972.9 KFP17779.1 - 3.1 6.5 5.5 0.37 9.5 0.3 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TMIE PF16038.5 KFP17779.1 - 9.6 6.1 7.0 21 5.0 7.0 1.5 1 0 0 1 1 1 0 TMIE protein IQ PF00612.27 KFP17781.1 - 0.0093 15.7 0.5 0.013 15.2 0.5 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ig_2 PF13895.6 KFP17784.1 - 2.5e-06 27.7 0.0 4.2e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFP17784.1 - 6.4e-05 23.5 0.0 0.0024 18.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Asp PF00026.23 KFP17786.1 - 7.4e-40 137.3 0.1 1.4e-39 136.4 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KFP17786.1 - 3.6e-13 49.6 0.0 5.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KFP17786.1 - 0.0042 17.3 0.1 0.022 15.0 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ILEI PF15711.5 KFP17787.1 - 1e-16 61.2 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Interleukin-like EMT inducer Dynamin_M PF01031.20 KFP17789.1 - 1.1e-78 264.4 15.8 1.1e-78 264.4 15.8 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFP17789.1 - 1.5e-46 158.6 0.3 5.9e-46 156.6 0.0 2.2 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 KFP17789.1 - 8.1e-18 64.4 0.1 8.5e-17 61.1 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFP17789.1 - 0.00022 21.3 0.1 0.0021 18.1 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP17789.1 - 0.0011 19.3 0.9 0.033 14.6 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain CHDNT PF08073.12 KFP17789.1 - 0.003 17.5 0.1 0.026 14.5 0.1 2.7 3 0 0 3 3 3 1 CHDNT (NUC034) domain AAA_21 PF13304.6 KFP17789.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFP17789.1 - 0.071 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KFP17789.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.9 2 1 1 3 3 2 0 AAA ATPase domain ABC_tran PF00005.27 KFP17789.1 - 0.25 11.9 2.2 0.43 11.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Mt_ATP-synt_B PF05405.14 KFP17789.1 - 0.75 9.4 9.8 0.078 12.6 1.2 2.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) P4Ha_N PF08336.11 KFP17789.1 - 9 6.3 9.2 0.81 9.7 0.1 3.3 2 1 1 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Trypsin PF00089.26 KFP17790.1 - 2.2e-68 230.4 1.4 3.1e-68 229.9 1.4 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFP17790.1 - 3.9e-31 107.5 0.1 8.4e-31 106.4 0.1 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP17790.1 - 2.8e-10 40.7 0.0 6.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Hepsin, SRCR domain DUF1986 PF09342.11 KFP17790.1 - 8.2e-09 35.9 0.1 8.2e-09 35.9 0.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1986) SRCR PF00530.18 KFP17790.1 - 9.1e-06 26.1 0.0 3.4e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFP17790.1 - 3.9e-05 24.6 0.0 8.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 KFP17790.1 - 0.00071 19.7 5.4 0.0021 18.2 5.4 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF3149 PF11346.8 KFP17790.1 - 0.048 13.3 1.9 0.1 12.2 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) zf-C2H2 PF00096.26 KFP17791.1 - 4.3e-47 156.0 140.7 7.7e-06 26.1 1.1 17.8 18 0 0 18 18 17 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17791.1 - 5.6e-44 145.0 129.0 0.00056 20.5 0.5 18.1 18 0 0 18 18 18 16 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP17791.1 - 1.1e-30 104.7 112.6 1.4e-05 25.3 0.5 17.6 18 0 0 18 18 17 10 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP17791.1 - 4.4e-21 74.6 94.8 0.0065 16.7 0.8 17.7 18 0 0 18 18 18 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP17791.1 - 2.5e-16 59.5 106.2 0.012 16.0 0.2 16.9 18 0 0 18 18 17 12 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP17791.1 - 9.6e-06 25.5 108.7 0.27 11.3 0.0 16.8 17 0 0 17 17 17 6 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP17791.1 - 3.5e-05 23.6 46.7 0.021 14.7 0.2 10.7 11 0 0 11 11 11 4 zinc-finger of a C2HC-type zf_PR_Knuckle PF18445.1 KFP17791.1 - 0.00048 19.9 0.6 0.00048 19.9 0.6 4.3 3 0 0 3 3 3 1 PR zinc knuckle motif SET PF00856.28 KFP17791.1 - 0.0027 18.1 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 SET domain zf-MYST PF17772.1 KFP17791.1 - 0.015 14.9 0.9 0.015 14.9 0.9 9.6 9 2 2 11 11 11 0 MYST family zinc finger domain BolA PF01722.18 KFP17791.1 - 0.1 12.9 13.9 54 4.2 0.1 7.0 5 2 3 8 8 8 0 BolA-like protein zinc_ribbon_15 PF17032.5 KFP17791.1 - 0.8 10.5 71.4 2 9.2 0.8 9.5 7 2 2 10 10 9 0 zinc-ribbon family GAGA PF09237.11 KFP17791.1 - 5.8 6.8 14.1 6.7 6.6 0.2 5.2 5 1 0 5 5 5 0 GAGA factor zf-C2H2_3rep PF18868.1 KFP17791.1 - 7.8 7.2 57.6 1.9 9.2 1.3 9.0 3 1 3 8 8 8 0 Zinc finger C2H2-type, 3 repeats SMP_C2CD2L PF18696.1 KFP17792.1 - 1.3e-44 151.7 4.7 1.6e-44 151.4 2.9 2.1 2 0 0 2 2 2 1 Synaptotagmin-like, mitochondrial and lipid-binding domain C2 PF00168.30 KFP17792.1 - 3.5e-09 36.9 0.1 1.5e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain DOCK-C2 PF14429.6 KFP17792.1 - 0.049 13.4 0.3 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.6 KFP17792.1 - 0.1 12.2 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 CEP76 C2 domain BTB PF00651.31 KFP17793.1 - 6.7e-26 90.7 0.1 1.3e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf_C2H2_6 PF18450.1 KFP17793.1 - 1.3e-18 66.3 5.8 1.3e-18 66.3 5.8 3.6 3 0 0 3 3 3 1 Zinc Finger domain zf-C2H2 PF00096.26 KFP17793.1 - 1.5e-15 56.7 69.8 0.00089 19.6 1.7 9.3 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17793.1 - 8.7e-15 54.2 72.4 0.013 16.2 0.9 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP17793.1 - 0.0063 16.9 4.7 0.0063 16.9 4.7 10.7 11 1 0 11 11 11 3 Zinc-finger double domain zf-met PF12874.7 KFP17793.1 - 0.014 15.8 39.2 0.042 14.2 2.4 7.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP17793.1 - 0.021 15.3 33.6 0.044 14.2 0.0 6.5 5 2 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Desulfoferrod_N PF06397.12 KFP17793.1 - 0.42 10.3 8.1 50 3.6 0.1 4.7 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-MYST PF17772.1 KFP17793.1 - 0.53 9.9 0.0 0.53 9.9 0.0 6.7 7 2 2 9 9 9 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KFP17793.1 - 2.1 8.5 53.5 0.51 10.4 0.5 8.3 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP17793.1 - 2.3 8.6 50.6 0.14 12.5 2.3 8.8 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding PknG_rubred PF16919.5 KFP17793.1 - 8.2 6.6 6.6 9.8 6.3 0.0 3.7 4 0 0 4 4 4 0 Protein kinase G rubredoxin domain Trefoil PF00088.18 KFP17795.1 - 4.2e-26 90.6 25.1 3.4e-13 49.3 7.1 2.3 2 1 0 2 2 2 2 Trefoil (P-type) domain TEX29 PF15839.5 KFP17795.1 - 6.3 7.5 9.9 4.7 7.9 1.8 2.8 1 1 1 2 2 2 0 Testis-expressed sequence 29 protein Trypsin PF00089.26 KFP17796.1 - 3.1e-73 246.2 0.6 4.5e-73 245.7 0.6 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.6 KFP17796.1 - 7.8e-26 90.5 1.1 1.4e-25 89.7 1.1 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP17796.1 - 8.4e-10 39.1 0.6 1.9e-09 38.0 0.6 1.5 1 0 0 1 1 1 1 Hepsin, SRCR domain SRCR PF00530.18 KFP17796.1 - 5.8e-07 29.9 0.1 1.9e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.11 KFP17796.1 - 1.2e-06 28.9 0.1 2.5e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFP17796.1 - 7.2e-06 26.1 8.0 2.3e-05 24.5 8.0 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Trypsin_2 PF13365.6 KFP17796.1 - 1.1e-05 26.4 0.0 2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain His_Phos_1 PF00300.22 KFP17797.1 - 1.8e-18 67.0 0.0 3.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.6 KFP17797.1 - 8.7e-14 51.1 0.0 1.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP17797.1 - 0.00024 20.6 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP17797.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain 2_5_RNA_ligase2 PF13563.6 KFP17797.1 - 0.011 15.6 0.1 0.033 14.1 0.1 1.8 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KFP17797.1 - 0.057 13.6 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 LigT like Phosphoesterase UBA PF00627.31 KFP17797.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain MORN PF02493.20 KFP17798.1 - 1.2e-34 116.1 44.9 4.3e-10 38.9 3.4 7.4 7 0 0 7 7 7 7 MORN repeat MFS_1 PF07690.16 KFP17799.1 - 2.5e-34 118.8 38.7 9.4e-30 103.7 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2985 PF11204.8 KFP17799.1 - 0.018 15.2 3.2 1.4 9.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) MFS_1_like PF12832.7 KFP17799.1 - 0.034 13.0 16.5 0.027 13.4 8.3 2.6 2 1 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 KFP17799.1 - 3.4 6.4 28.7 0.047 12.6 5.9 3.0 2 2 0 2 2 2 0 Sugar (and other) transporter PDEase_I PF00233.19 KFP17800.1 - 6.9e-87 291.1 4.2 6.9e-87 291.1 4.2 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase 4HB_MCP_1 PF12729.7 KFP17800.1 - 0.11 12.0 1.6 0.19 11.2 0.2 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction WD40 PF00400.32 KFP17801.1 - 4.7e-09 36.7 0.2 0.38 11.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat HPS3_N PF14761.6 KFP17801.1 - 0.0072 15.9 0.0 0.51 9.8 0.0 2.7 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 ANAPC4_WD40 PF12894.7 KFP17801.1 - 0.12 12.6 0.0 4.3 7.7 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NDUFV3 PF15880.5 KFP17802.1 - 2e-14 53.3 0.4 3.5e-14 52.5 0.4 1.4 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial AF-4 PF05110.13 KFP17802.1 - 0.019 13.1 30.2 0.026 12.7 30.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2124 PF09897.9 KFP17802.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Meis_PKNOX_N PF16493.5 KFP17803.1 - 4.2e-37 126.3 0.1 8e-37 125.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFP17803.1 - 7.5e-20 70.5 1.2 1.8e-19 69.3 1.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP17803.1 - 4.8e-08 32.7 0.3 9.5e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 Homeodomain CBS PF00571.28 KFP17804.1 - 1.1e-08 35.4 0.0 1.5e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 CBS domain Poxvirus_B22R_C PF13168.6 KFP17804.1 - 0.0083 15.6 0.0 0.0098 15.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal PALP PF00291.25 KFP17805.1 - 4.2e-16 59.2 0.0 4.4e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_tran_WecB PF03808.13 KFP17805.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family LSDAT_prok PF18171.1 KFP17805.1 - 0.034 13.4 0.1 0.041 13.1 0.1 1.1 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Methyltransf_25 PF13649.6 KFP17805.1 - 0.062 14.0 0.0 0.092 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DAGK_cat PF00781.24 KFP17805.1 - 0.077 12.6 0.1 0.087 12.4 0.1 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Tubulin PF00091.25 KFP17805.1 - 0.11 12.6 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Methyltransf_12 PF08242.12 KFP17805.1 - 0.13 13.1 0.0 0.18 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Bmp PF02608.14 KFP17805.1 - 0.22 10.5 0.0 0.22 10.5 0.0 1.0 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like PALP PF00291.25 KFP17806.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 KFP17807.1 - 5.6e-67 226.2 0.0 7.2e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFP17807.1 - 3.2e-10 40.3 0.7 5.5e-08 33.1 0.1 3.1 3 0 0 3 3 3 2 CBS domain zf-CCCH PF00642.24 KFP17809.1 - 5.2e-14 51.7 17.1 8.2e-07 28.8 3.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFP17809.1 - 6e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KFP17809.1 - 2.1e-06 28.4 2.1 0.05 14.3 0.1 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFP17809.1 - 1.5e-05 24.9 14.4 0.0099 15.9 2.9 2.5 2 0 0 2 2 2 2 Zinc finger domain KMP11 PF03037.16 KFP17809.1 - 0.0083 16.9 0.5 0.48 11.2 0.3 2.2 2 0 0 2 2 2 1 Kinetoplastid membrane protein 11 Nup35_RRM_2 PF14605.6 KFP17809.1 - 0.04 13.9 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 KFP17809.1 - 0.053 13.7 5.5 1.1 9.5 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger containing family CART PF06373.11 KFP17809.1 - 0.63 10.3 3.7 2.4 8.4 0.6 3.0 3 1 1 4 4 4 0 Cocaine and amphetamine regulated transcript protein (CART) Crystallin PF00525.18 KFP17810.1 - 2.7e-24 85.1 1.9 4.8e-24 84.3 1.9 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal HSP20 PF00011.21 KFP17810.1 - 7.7e-24 83.8 0.0 9.4e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pkinase PF00069.25 KFP17812.1 - 2.5e-68 230.3 0.0 4.2e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17812.1 - 2.7e-35 121.9 0.0 4.5e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP17812.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP17812.1 - 1.8e-06 27.1 0.1 4.1e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP17812.1 - 0.078 12.3 0.3 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF383 PF04063.14 KFP17813.1 - 0.0072 16.0 0.2 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF383) VHS PF00790.19 KFP17813.1 - 0.0077 16.1 0.1 0.54 10.1 0.0 2.6 2 0 0 2 2 2 1 VHS domain Exonuc_VII_L PF02601.15 KFP17813.1 - 0.013 15.0 1.2 0.019 14.6 1.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KFP17813.1 - 0.02 12.5 4.1 0.026 12.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RasGEF_N_2 PF14663.6 KFP17813.1 - 0.031 14.7 0.6 0.24 11.8 0.1 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain YabA PF06156.13 KFP17813.1 - 0.042 14.5 5.3 0.16 12.6 5.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA CCCAP PF15964.5 KFP17813.1 - 0.079 11.2 11.1 0.19 9.9 9.2 2.0 2 0 0 2 2 2 0 Centrosomal colon cancer autoantigen protein family DUF1664 PF07889.12 KFP17813.1 - 0.28 11.2 6.9 19 5.3 0.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.13 KFP17813.1 - 0.45 10.7 5.0 0.7 10.1 2.4 2.2 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal UPF0242 PF06785.11 KFP17813.1 - 0.48 10.5 10.9 0.048 13.8 6.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KFP17813.1 - 0.56 9.2 5.1 1.2 8.1 3.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mis14 PF08641.12 KFP17813.1 - 0.6 10.4 8.9 0.098 13.0 4.8 1.8 2 0 0 2 2 2 0 Kinetochore protein Mis14 like DUF4201 PF13870.6 KFP17813.1 - 1.2 8.9 13.4 0.24 11.1 9.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) YlqD PF11068.8 KFP17813.1 - 2.1 8.7 9.5 0.51 10.7 5.6 1.9 2 0 0 2 2 2 0 YlqD protein Lectin_N PF03954.14 KFP17813.1 - 3.3 7.5 8.0 5.6 6.7 4.2 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Nop52 PF05997.12 KFP17814.1 - 2.2e-61 207.4 4.5 6.4e-61 205.9 4.5 1.7 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Phos_pyr_kin PF08543.12 KFP17815.1 - 6.7e-19 68.2 0.0 1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFP17815.1 - 5.1e-11 42.4 0.0 1.5e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HpcH_HpaI PF03328.14 KFP17815.1 - 0.0039 16.4 0.0 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SRR1 PF07985.12 KFP17815.1 - 0.0085 16.1 0.1 0.037 14.1 0.0 2.0 2 0 0 2 2 2 1 SRR1 Acyltransf_C PF16076.5 KFP17816.1 - 2.3e-28 98.1 0.2 4.4e-28 97.2 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFP17816.1 - 7.8e-15 54.7 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TRAPPC10 PF12584.8 KFP17818.1 - 0.00021 21.0 0.3 0.00045 19.9 0.0 1.7 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 TRAPPC10 PF12584.8 KFP17819.1 - 6.3e-28 97.4 0.0 7.5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KFP17819.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking WD40 PF00400.32 KFP17820.1 - 1.8e-32 110.9 25.5 9.8e-08 32.6 0.0 11.6 13 0 0 13 13 13 4 WD domain, G-beta repeat Utp12 PF04003.12 KFP17820.1 - 3.1e-24 85.3 0.8 5.1e-24 84.6 0.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFP17820.1 - 2.3e-19 69.5 0.0 0.011 16.1 0.0 9.1 4 3 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP17820.1 - 2.6e-08 34.0 0.7 0.012 15.5 0.0 4.7 2 1 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP17820.1 - 1.7e-07 30.5 0.2 0.34 9.8 0.1 4.3 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP17820.1 - 2e-05 24.1 0.5 0.0002 20.8 0.2 2.6 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KFP17820.1 - 6.2e-05 22.8 0.1 0.42 10.6 0.0 4.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Utp13 PF08625.11 KFP17820.1 - 0.018 14.9 0.2 0.06 13.2 0.2 1.9 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Osmo_MPGsynth PF09488.10 KFP17820.1 - 0.03 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DJ-1_PfpI PF01965.24 KFP17821.1 - 8.5e-07 28.9 0.2 3.1e-06 27.1 0.2 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family V-set PF07686.17 KFP17822.1 - 3e-11 43.5 0.6 4.5e-11 42.9 0.6 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP17822.1 - 6.4e-06 26.7 2.4 3.8e-05 24.2 0.6 2.6 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP17822.1 - 2e-05 24.6 3.4 0.00049 20.2 3.2 2.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP17822.1 - 0.00077 19.8 0.4 0.0024 18.2 0.4 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP17822.1 - 0.0029 17.6 0.2 0.025 14.6 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set_CD47 PF08204.11 KFP17822.1 - 0.0069 16.4 0.1 0.009 16.0 0.1 1.2 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain NMDAR2_C PF10565.9 KFP17822.1 - 0.016 14.1 0.2 0.018 14.0 0.2 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Herpes_gE PF02480.16 KFP17822.1 - 0.039 12.7 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 KFP17822.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain AA_kinase PF00696.28 KFP17823.1 - 8.8e-41 140.1 0.3 1.6e-40 139.3 0.3 1.4 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 KFP17823.1 - 1e-07 30.8 0.2 0.19 10.2 0.0 3.2 3 0 0 3 3 3 3 Aldehyde dehydrogenase family 7tm_1 PF00001.21 KFP17825.1 - 1.2e-44 152.6 12.0 1.4e-44 152.4 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17825.1 - 1.5e-07 31.0 8.8 1.8e-07 30.8 8.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 KFP17825.1 - 1.9e-06 27.4 2.9 1.9e-06 27.4 2.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.9 KFP17825.1 - 1.7e-05 24.3 6.7 5.3e-05 22.6 6.0 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 KFP17825.1 - 0.00013 21.8 9.2 0.0012 18.6 9.2 2.0 1 1 0 1 1 1 1 Olfactory receptor Exo_endo_phos PF03372.23 KFP17826.1 - 2.2e-14 53.6 0.0 2.7e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SAP PF02037.27 KFP17827.1 - 4.9e-10 38.9 1.4 1.1e-08 34.7 0.9 2.5 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KFP17827.1 - 0.0036 17.1 10.2 0.4 10.5 1.6 3.9 1 1 3 4 4 4 4 Tho1/MOS11 C-terminal domain ORMDL PF04061.14 KFP17828.1 - 1.2e-52 177.3 0.9 1.4e-52 177.1 0.9 1.0 1 0 0 1 1 1 1 ORMDL family DEAD PF00270.29 KFP17829.1 - 1.5e-44 151.9 0.1 3.9e-44 150.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP17829.1 - 1.6e-25 89.6 0.0 8.9e-25 87.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFP17829.1 - 7.7e-15 54.9 0.1 1.6e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFP17829.1 - 3.4e-07 30.4 0.0 1.2e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFP17829.1 - 0.0016 17.7 0.0 0.0062 15.8 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Med29 PF11568.8 KFP17829.1 - 0.043 14.0 1.4 1.9 8.7 0.1 3.2 3 0 0 3 3 3 0 Mediator complex subunit 29 FF PF01846.19 KFP17829.1 - 0.059 13.6 1.3 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 FF domain TFIIIC_delta PF12657.7 KFP17830.1 - 2.6e-29 102.5 0.0 6.9e-28 97.8 0.0 2.4 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KFP17830.1 - 1.3e-09 37.9 2.0 1.3e-09 37.9 2.0 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex dCache_1 PF02743.18 KFP17831.1 - 0.14 12.0 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Cache domain ADK PF00406.22 KFP17831.1 - 0.2 11.8 0.1 0.23 11.5 0.1 1.1 1 0 0 1 1 1 0 Adenylate kinase ADK PF00406.22 KFP17832.1 - 4.6e-43 146.9 0.0 6e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFP17832.1 - 1.7e-22 80.3 0.0 6.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP17832.1 - 1.2e-14 54.9 0.0 6.5e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFP17832.1 - 5.7e-13 49.2 0.0 1.3e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Hydin_ADK PF17213.3 KFP17832.1 - 1.4e-11 45.1 0.0 0.039 14.2 0.0 4.1 4 0 0 4 4 4 3 Hydin Adenylate kinase-like domain AAA PF00004.29 KFP17832.1 - 2.3e-09 37.8 0.1 0.00057 20.3 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP17832.1 - 5.6e-06 26.2 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFP17832.1 - 9e-06 26.2 0.0 0.091 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain KTI12 PF08433.10 KFP17832.1 - 1.4e-05 24.7 0.0 0.026 14.0 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_22 PF13401.6 KFP17832.1 - 0.00017 21.9 0.1 0.48 10.7 0.0 2.8 3 1 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 KFP17832.1 - 0.00057 19.3 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KFP17832.1 - 0.00081 19.7 0.0 0.012 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFP17832.1 - 0.0009 19.6 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFP17832.1 - 0.0015 18.8 0.0 0.78 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP17832.1 - 0.0019 18.2 0.1 3.1 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFP17832.1 - 0.002 17.9 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KFP17832.1 - 0.0028 17.4 0.0 0.83 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFP17832.1 - 0.0032 18.0 0.0 1.6 9.2 0.0 2.4 2 1 0 2 2 2 1 ABC transporter PMBR PF09373.10 KFP17832.1 - 0.0054 16.8 0.0 0.2 11.9 0.0 2.7 2 0 0 2 2 2 1 Pseudomurein-binding repeat Cytidylate_kin PF02224.18 KFP17832.1 - 0.0057 16.4 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase Sigma54_activ_2 PF14532.6 KFP17832.1 - 0.012 15.7 0.0 4.3 7.5 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF3987 PF13148.6 KFP17832.1 - 0.02 13.9 0.0 0.15 11.1 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Rad17 PF03215.15 KFP17832.1 - 0.027 14.4 0.2 5 7.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KFP17832.1 - 0.027 14.4 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.15 KFP17832.1 - 0.036 14.1 0.0 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KFP17832.1 - 0.049 13.1 0.0 9.8 5.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KFP17832.1 - 0.054 13.2 0.0 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase AAA_25 PF13481.6 KFP17832.1 - 0.056 13.0 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP17832.1 - 0.078 12.7 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 KFP17832.1 - 0.082 12.7 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFP17832.1 - 0.098 11.8 0.0 5.4 6.1 0.0 2.6 3 0 0 3 3 3 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KFP17832.1 - 0.12 11.6 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KFP17832.1 - 0.16 11.7 0.0 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain SPACA9 PF15120.6 KFP17833.1 - 4.4e-79 264.0 0.9 4.9e-79 263.8 0.9 1.0 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 zf-H2C2_2 PF13465.6 KFP17834.1 - 3.4e-24 84.1 36.2 9.2e-08 32.2 2.0 6.7 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP17834.1 - 1.4e-22 78.8 42.7 2e-05 24.8 2.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17834.1 - 2.5e-15 55.9 40.3 0.0053 17.5 0.7 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP17834.1 - 9.7e-12 44.9 23.1 0.039 14.2 0.1 6.0 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP17834.1 - 1.1e-08 34.9 35.2 0.0025 17.8 2.8 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 KFP17834.1 - 5.4e-06 26.6 31.8 0.0077 16.6 0.3 6.1 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-CHCC PF10276.9 KFP17834.1 - 0.0011 18.9 6.6 0.44 10.6 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger domain C1_1 PF00130.22 KFP17834.1 - 0.0013 18.6 12.3 0.47 10.4 2.5 4.0 3 2 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 KFP17834.1 - 0.0028 17.8 19.3 0.046 13.9 2.4 3.4 2 1 1 3 3 3 2 FYVE zinc finger Ta0938 PF11494.8 KFP17834.1 - 0.0046 17.2 0.3 2 8.7 0.1 2.8 2 1 1 3 3 3 1 Ta0938 zf-C2H2_3rep PF18868.1 KFP17834.1 - 0.015 16.0 15.9 1.6 9.4 2.2 4.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 KFP17834.1 - 0.015 15.4 17.3 3.6 7.8 0.2 5.5 5 0 0 5 5 5 0 AN1-like Zinc finger Prok-RING_1 PF14446.6 KFP17834.1 - 0.028 14.4 11.3 8.7 6.4 0.1 5.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-C2H2_8 PF15909.5 KFP17834.1 - 0.066 13.5 18.2 0.34 11.2 2.1 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFP17834.1 - 0.11 12.6 17.0 0.7 10.1 1.0 4.1 3 2 2 5 5 5 0 Zinc ribbon domain zf_UBZ PF18439.1 KFP17834.1 - 0.25 11.0 15.4 7.1 6.3 0.3 4.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KFP17834.1 - 0.29 11.2 8.8 1.1 9.3 2.8 2.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GAGA PF09237.11 KFP17834.1 - 0.29 11.0 7.4 7.1 6.5 0.1 3.5 3 1 1 4 4 3 0 GAGA factor HNH_5 PF14279.6 KFP17834.1 - 0.43 10.5 14.8 4.1 7.3 0.9 5.0 3 2 1 4 4 4 0 HNH endonuclease zf-C2H2_12 PF18658.1 KFP17834.1 - 0.5 10.0 6.6 2.3 7.9 4.3 3.1 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-Di19 PF05605.12 KFP17834.1 - 0.54 10.6 29.2 0.11 12.8 4.9 4.0 3 2 0 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 KFP17834.1 - 0.96 9.8 7.2 3.8 7.9 2.0 3.3 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_11 PF16622.5 KFP17834.1 - 1 9.2 19.1 8.2 6.3 0.1 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type XPA_N PF01286.18 KFP17834.1 - 1.2 9.3 13.2 7.6 6.7 0.1 5.1 5 0 0 5 5 5 0 XPA protein N-terminal Mut7-C PF01927.16 KFP17834.1 - 1.3 9.1 6.1 2.8 8.1 0.4 2.5 1 1 1 2 2 2 0 Mut7-C RNAse domain DUF2256 PF10013.9 KFP17834.1 - 1.4 9.1 12.7 47 4.2 0.1 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_15 PF17032.5 KFP17834.1 - 2 9.2 11.4 4.4 8.1 2.4 3.2 1 1 2 3 3 3 0 zinc-ribbon family PyrI_C PF02748.15 KFP17834.1 - 4.1 7.4 13.7 0.68 9.9 0.2 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.6 KFP17834.1 - 4.3 7.3 19.8 1.7 8.7 1.0 4.3 5 0 0 5 5 4 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 KFP17834.1 - 5.6 7.1 17.2 11 6.2 0.6 4.9 2 2 3 5 5 5 0 KIAA1045 RING finger ADK_lid PF05191.14 KFP17834.1 - 5.7 7.0 9.2 8.5 6.4 2.9 3.2 2 1 1 3 3 3 0 Adenylate kinase, active site lid Sprouty PF05210.13 KFP17834.1 - 6.1 7.3 10.9 4 7.9 0.4 3.3 2 1 1 3 3 3 0 Sprouty protein (Spry) zf-C2H2_2 PF12756.7 KFP17834.1 - 6.9 7.1 23.7 9.9 6.6 0.3 5.4 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 KFP17834.1 - 7.2 6.7 14.4 12 5.9 1.1 4.1 1 1 1 2 2 1 0 zinc-ribbons TB2_DP1_HVA22 PF03134.19 KFP17835.1 - 6.8e-28 96.4 4.7 7.8e-28 96.2 4.7 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_S19 PF00203.21 KFP17836.1 - 1.1e-39 134.1 0.3 1.4e-39 133.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 RRM_1 PF00076.22 KFP17837.1 - 7.7e-37 125.0 0.2 8.8e-18 63.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP17837.1 - 3.8e-13 49.4 0.3 2.3e-07 30.8 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP17837.1 - 1.5e-05 24.9 0.2 0.062 13.3 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP17837.1 - 0.0003 21.1 0.2 0.54 10.5 0.0 3.0 2 2 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter CSD PF00313.22 KFP17837.1 - 0.029 14.2 1.1 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF4651 PF15513.6 KFP17837.1 - 0.16 11.8 0.2 7.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Spore_YabQ PF09578.10 KFP17838.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Oxidored_q6 PF01058.22 KFP17839.1 - 1.2e-06 28.4 0.1 2.8e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.25 KFP17840.1 - 4e-52 177.2 0.0 4.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17840.1 - 1.3e-17 64.0 0.0 1.5e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP17840.1 - 6.7e-05 22.3 0.0 9.1e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP17840.1 - 0.034 13.5 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP17840.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KFP17840.1 - 0.17 11.4 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFP17840.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GTP_EFTU PF00009.27 KFP17841.1 - 1.8e-54 184.2 0.0 2.6e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFP17841.1 - 2.3e-40 137.4 0.0 5e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFP17841.1 - 4.1e-15 55.9 1.9 6.3e-15 55.3 0.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP17841.1 - 0.00031 20.8 0.2 0.0083 16.2 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KFP17841.1 - 0.017 15.0 1.2 0.031 14.2 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KFP17841.1 - 0.079 13.0 0.1 17 5.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KFP17841.1 - 0.24 10.5 0.2 0.7 9.0 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit T-box PF00907.22 KFP17844.1 - 2e-25 90.2 0.2 3e-25 89.6 0.2 1.3 1 0 0 1 1 1 1 T-box Got1 PF04178.12 KFP17845.1 - 7.5e-38 129.4 17.8 1.1e-37 128.8 16.5 1.7 1 1 1 2 2 2 2 Got1/Sft2-like family DUF4064 PF13273.6 KFP17845.1 - 0.028 14.7 10.4 0.22 11.8 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Bac_export_2 PF01312.19 KFP17845.1 - 0.5 9.5 6.6 2.3 7.3 6.6 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family MPC PF03650.13 KFP17846.1 - 1.5e-31 108.8 0.1 1.8e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Pkinase PF00069.25 KFP17847.1 - 1.4e-147 490.2 0.0 7e-75 251.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17847.1 - 3.4e-77 259.2 0.0 7e-41 140.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP17847.1 - 1.9e-13 50.4 0.0 5.3e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KFP17847.1 - 4.1e-10 39.4 0.0 8.6e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 KFP17847.1 - 4.6e-08 33.7 2.2 1.3e-07 32.2 2.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KFP17847.1 - 4.6e-07 29.0 0.0 0.006 15.4 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 KFP17847.1 - 5.7e-06 26.4 0.0 0.21 11.5 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFP17847.1 - 2.9e-05 23.8 0.1 0.88 9.2 0.0 3.3 3 0 0 3 3 3 3 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFP17847.1 - 5.6e-05 22.3 0.1 0.029 13.3 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 KFP17847.1 - 0.00094 18.7 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFP17847.1 - 0.0052 16.4 0.3 0.35 10.5 0.0 2.6 3 0 0 3 3 3 1 RIO1 family Ribonuclease_T2 PF00445.18 KFP17849.1 - 2.1e-55 187.8 9.3 2.4e-55 187.6 9.3 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family RVT_1 PF00078.27 KFP17851.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Death PF00531.22 KFP17852.1 - 4.1e-06 26.9 1.7 8.4e-06 25.9 1.7 1.6 1 0 0 1 1 1 1 Death domain ZU5 PF00791.20 KFP17852.1 - 0.016 15.5 0.6 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 ZU5 domain HA2 PF04408.23 KFP17854.1 - 5.7e-20 71.6 0.0 1.8e-19 70.0 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP17854.1 - 1.1e-11 44.9 0.1 3.6e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Pox_D2 PF04701.13 KFP17854.1 - 0.2 11.9 2.4 2.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Pox virus D2 protein BCIP PF13862.6 KFP17855.1 - 2.9e-57 193.8 4.7 4.9e-57 193.0 4.7 1.3 1 1 0 1 1 1 1 p21-C-terminal region-binding protein DPRP PF04244.13 KFP17855.1 - 0.097 12.5 0.1 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein HEM4 PF02602.15 KFP17856.1 - 2e-48 164.8 0.0 2.2e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF2315 PF10231.9 KFP17857.1 - 0.41 10.7 4.0 1 9.5 1.8 2.5 2 0 0 2 2 2 0 Apoptogenic protein 1 TPR_2 PF07719.17 KFP17857.1 - 0.54 10.5 11.2 0.66 10.2 0.7 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP17857.1 - 1 9.7 6.2 16 6.0 1.3 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP17857.1 - 6.1 6.8 6.1 6.7 6.7 0.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 KFP17858.1 - 3.2e-55 186.3 0.0 5.6e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP17858.1 - 2.3e-19 69.4 0.0 4e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFP17858.1 - 0.033 14.4 0.0 0.088 13.0 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AnkUBD PF18418.1 KFP17859.1 - 8.8e-55 182.8 0.1 1.7e-54 181.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin ubiquitin-binding domain OTU PF02338.19 KFP17859.1 - 4.2e-38 130.7 0.1 1.1e-37 129.4 0.1 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease zf-RanBP PF00641.18 KFP17859.1 - 1e-10 40.7 30.5 7.4e-06 25.2 6.2 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KFP17859.1 - 0.024 14.7 13.6 0.7 10.0 7.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon Cluap1 PF10234.9 KFP17860.1 - 0.0024 17.3 1.8 0.0035 16.8 1.8 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Pepdidase_M14_N PF18027.1 KFP17860.1 - 0.065 13.6 0.5 4.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain Spore_II_R PF09551.10 KFP17860.1 - 0.26 11.7 2.3 0.28 11.6 0.8 1.7 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) COG2 PF06148.11 KFP17860.1 - 0.48 10.5 3.7 0.86 9.7 3.7 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Methyltransf_31 PF13847.6 KFP17861.1 - 4.5e-21 75.2 0.0 6.1e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP17861.1 - 6.6e-12 46.0 0.0 1e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP17861.1 - 3.8e-09 36.6 0.0 8.6e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP17861.1 - 2e-08 34.9 0.0 2.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP17861.1 - 4.3e-08 33.7 0.0 6.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFP17861.1 - 2.8e-07 30.2 0.0 3.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFP17861.1 - 1.5e-06 27.8 0.0 2.3e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KFP17861.1 - 0.00024 20.5 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KFP17861.1 - 0.00083 19.0 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KFP17861.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 KFP17861.1 - 0.0031 17.5 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFP17861.1 - 0.0036 16.7 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KFP17861.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFP17861.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 KFP17861.1 - 0.031 14.6 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Cons_hypoth95 PF03602.15 KFP17861.1 - 0.035 13.8 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 KFP17861.1 - 0.035 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 KFP17861.1 - 0.054 12.6 0.0 0.13 11.4 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_24 PF13578.6 KFP17861.1 - 0.071 14.1 0.0 0.095 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase_like PF13242.6 KFP17862.1 - 8.9e-21 73.8 0.0 1.9e-19 69.5 0.1 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFP17862.1 - 6.6e-09 35.8 0.0 1.5e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP17862.1 - 1.1e-08 35.4 0.1 4.9e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP17862.1 - 2.7e-05 24.5 0.4 0.00022 21.6 0.4 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_3 PF00202.21 KFP17863.1 - 2e-122 408.8 0.0 2.4e-122 408.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFP17863.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Sulfotransfer_1 PF00685.27 KFP17864.1 - 6.1e-16 58.7 0.0 7.8e-13 48.5 0.1 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP17864.1 - 2.7e-13 50.8 0.1 9.8e-13 49.0 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family PVL_ORF50 PF07768.11 KFP17864.1 - 0.075 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 PVL ORF-50-like family Peptidase_M14 PF00246.24 KFP17865.1 - 1.4e-73 248.2 0.1 2.4e-73 247.5 0.1 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.25 KFP17865.1 - 2.9e-27 95.3 0.1 1.2e-26 93.4 0.1 2.1 2 0 0 2 2 2 1 F5/8 type C domain CarboxypepD_reg PF13620.6 KFP17865.1 - 6.1e-13 48.8 0.1 1.4e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP17865.1 - 3.9e-06 26.8 0.1 8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 KFP17865.1 - 0.0034 17.2 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 PEGA domain 7tm_1 PF00001.21 KFP17867.1 - 2.4e-37 128.7 15.5 3.1e-37 128.3 15.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP17867.1 - 6e-08 32.6 16.5 6e-08 32.6 16.5 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFP17867.1 - 1.4e-05 25.0 10.5 2.3e-05 24.3 10.3 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srbc PF10316.9 KFP17867.1 - 0.032 13.7 15.3 0.031 13.8 13.5 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc TssO PF17561.2 KFP17867.1 - 0.32 11.1 6.7 0.92 9.6 0.5 2.6 2 0 0 2 2 2 0 Type VI secretion system, TssO WD40 PF00400.32 KFP17868.1 - 1.5e-22 79.5 2.8 2.4e-05 25.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17868.1 - 7.9e-07 29.3 0.0 1.2 9.5 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP17868.1 - 0.14 11.1 0.0 0.77 8.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Acyl-CoA_dh_1 PF00441.24 KFP17869.1 - 6.8e-51 172.4 0.7 1.6e-49 167.9 0.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP17869.1 - 1.4e-28 99.8 0.1 3e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP17869.1 - 1.4e-26 92.5 0.0 2.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP17869.1 - 4.5e-25 88.5 0.0 7.7e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-H2C2_2 PF13465.6 KFP17870.1 - 1.5e-12 47.3 45.0 3e-07 30.5 4.0 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP17870.1 - 2e-11 43.4 31.9 2.2e-05 24.1 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP17870.1 - 8e-07 29.2 49.3 0.067 13.7 7.9 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP17870.1 - 0.0025 18.5 44.6 0.75 10.8 6.7 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP17870.1 - 2.5 8.5 0.0 2.5 8.5 0.0 5.0 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) KTI12 PF08433.10 KFP17871.1 - 4e-15 56.0 1.6 5.5e-15 55.6 1.6 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFP17871.1 - 0.0038 17.4 0.1 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF4259 PF14078.6 KFP17871.1 - 0.043 14.6 1.2 0.075 13.8 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Reprolysin PF01421.19 KFP17872.1 - 3.2e-56 190.4 0.0 3.2e-56 190.4 0.0 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 KFP17872.1 - 1e-27 96.8 3.2 1e-27 96.8 3.2 3.9 3 2 2 5 5 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 KFP17872.1 - 7.5e-26 91.0 0.3 1.6e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin_5 PF13688.6 KFP17872.1 - 2e-20 73.8 0.2 2e-20 73.8 0.2 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KFP17872.1 - 2.2e-19 70.0 29.4 2.2e-19 70.0 29.4 3.5 3 1 0 3 3 2 1 Disintegrin Reprolysin_3 PF13582.6 KFP17872.1 - 1.7e-17 64.1 0.3 3.6e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP17872.1 - 1.3e-13 51.3 1.0 3.2e-13 50.0 1.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP17872.1 - 1.4e-10 41.2 0.2 2.4e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP17872.1 - 0.00058 19.7 0.1 0.00089 19.1 0.1 1.3 1 0 0 1 1 1 1 Matrixin EGF_2 PF07974.13 KFP17872.1 - 0.0016 18.7 12.5 0.0016 18.7 12.5 5.8 5 2 2 7 7 6 1 EGF-like domain EB PF01683.18 KFP17872.1 - 0.0026 18.0 11.6 0.0026 18.0 11.6 4.6 2 1 1 3 3 1 1 EB module Astacin PF01400.24 KFP17872.1 - 0.033 13.8 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 KFP17872.1 - 0.047 13.3 0.3 0.083 12.5 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 KFP17872.1 - 0.096 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4506 PF14958.6 KFP17873.1 - 1.1e-21 76.8 0.6 1.9e-21 76.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4506) AlaDh_PNT_C PF01262.21 KFP17873.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zona_pellucida PF00100.23 KFP17874.1 - 7.5e-05 22.7 0.7 7.5e-05 22.7 0.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFP17875.1 - 9.9e-30 104.2 2.2 1.1e-29 104.1 2.2 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFP17876.1 - 4e-10 39.9 0.1 4.3e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.18 KFP17877.1 - 2.7e-117 384.0 45.8 8.1e-32 109.7 6.9 4.1 3 1 1 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KFP17877.1 - 7.4e-16 58.5 16.8 0.0012 19.3 1.4 4.6 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KFP17877.1 - 6e-05 23.5 5.4 7.9 7.0 0.0 4.5 4 0 0 4 4 4 4 Hepsin, SRCR domain Zona_pellucida PF00100.23 KFP17878.1 - 1.3e-26 94.0 3.6 1.4e-26 93.9 3.6 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFP17879.1 - 8.9e-08 32.2 0.0 9.5e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain RRM_1 PF00076.22 KFP17880.1 - 0.0028 17.4 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 KFP17880.1 - 0.49 10.9 3.5 1 9.9 3.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FEZ PF07763.13 KFP17881.1 - 9.2 5.9 18.6 0.66 9.7 0.1 3.5 1 1 2 4 4 4 0 FEZ-like protein C2 PF00168.30 KFP17882.1 - 8.1e-69 228.4 0.0 2.9e-17 62.9 0.0 7.8 7 1 0 7 7 7 7 C2 domain FerB PF08150.12 KFP17882.1 - 5.3e-32 110.2 0.0 1.7e-31 108.6 0.0 2.0 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 KFP17882.1 - 2e-26 92.8 1.8 3.1e-22 79.2 0.1 2.6 1 1 1 2 2 2 2 Ferlin C-terminus FerI PF08151.12 KFP17882.1 - 3.2e-20 72.0 0.1 7.3e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain FerA PF08165.11 KFP17882.1 - 1.2e-19 69.9 0.4 2.7e-19 68.9 0.4 1.6 1 0 0 1 1 1 1 FerA (NUC095) domain Pex24p PF06398.11 KFP17882.1 - 2.5e-05 23.5 5.4 2.5e-05 23.5 5.4 3.8 3 1 1 4 4 4 2 Integral peroxisomal membrane peroxin PTEN_C2 PF10409.9 KFP17882.1 - 0.0016 18.2 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Synaptobrevin PF00957.21 KFP17882.1 - 3.7 7.4 4.1 8.1 6.3 4.1 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF4413 PF14372.6 KFP17883.1 - 0.068 13.5 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) SWIM PF04434.17 KFP17883.1 - 0.2 11.3 3.4 0.45 10.2 3.4 1.6 1 0 0 1 1 1 0 SWIM zinc finger UPF0542 PF15086.6 KFP17885.1 - 6.7e-32 109.2 2.2 7.6e-32 109.1 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 TMEM100 PF16311.5 KFP17885.1 - 0.13 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 NDUFA12 PF05071.16 KFP17886.1 - 5e-05 24.1 3.3 7.3e-05 23.5 3.3 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.32 KFP17888.1 - 2.3e-22 78.9 11.4 1.2e-06 29.2 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP17888.1 - 7.8e-09 35.7 0.1 0.023 15.0 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP17888.1 - 0.00039 19.2 1.0 1.4 7.5 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ELO PF01151.18 KFP17889.1 - 4.1e-62 210.0 28.0 4.8e-62 209.7 28.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DEP PF00610.21 KFP17891.1 - 3.1e-16 59.2 0.4 3.1e-15 56.0 0.0 2.6 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KFP17891.1 - 1.6e-07 31.2 0.5 5.9e-07 29.4 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain Ras PF00071.22 KFP17895.1 - 3.4e-61 205.6 2.2 4.1e-61 205.3 2.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP17895.1 - 1.7e-33 115.4 1.1 2.7e-33 114.7 1.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP17895.1 - 4e-14 52.5 0.3 5.5e-14 52.0 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP17895.1 - 4.9e-07 29.3 0.7 0.0002 20.8 0.1 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP17895.1 - 0.00015 21.8 0.1 0.00027 21.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP17895.1 - 0.00018 21.0 0.5 0.00025 20.5 0.5 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP17895.1 - 0.00019 21.0 0.1 0.00066 19.3 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2757 PF10955.8 KFP17895.1 - 0.0017 18.6 0.1 0.0034 17.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2757) FeoB_N PF02421.18 KFP17895.1 - 0.0035 16.9 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFP17895.1 - 0.0095 15.8 0.1 0.97 9.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KFP17895.1 - 0.01 15.2 0.2 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KFP17895.1 - 0.079 13.3 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 KFP17896.1 - 1.9e-61 207.3 0.0 3.4e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KFP17896.1 - 3.3e-07 30.8 0.0 8.6e-07 29.5 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP17896.1 - 6.5e-05 23.2 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP17896.1 - 0.00014 22.4 0.0 0.00086 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFP17896.1 - 0.00015 22.2 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP17896.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 KFP17896.1 - 0.00074 19.8 0.1 0.0022 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain RNA_helicase PF00910.22 KFP17896.1 - 0.0033 17.8 0.1 0.017 15.5 0.0 2.3 3 0 0 3 3 1 1 RNA helicase AAA_7 PF12775.7 KFP17896.1 - 0.0035 16.9 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KFP17896.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KFP17896.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KFP17896.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.11 KFP17896.1 - 0.055 13.7 0.1 0.26 11.5 0.0 2.2 3 0 0 3 3 1 0 Proteasome maturation factor UMP1 AAA_6 PF12774.7 KFP17896.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DMA PF03474.14 KFP17896.1 - 0.077 12.6 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 DMRTA motif NACHT PF05729.12 KFP17896.1 - 0.077 12.9 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 KFP17896.1 - 0.087 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KFP17896.1 - 0.11 13.1 0.4 0.42 11.1 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KFP17896.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFP17896.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP17897.1 - 2.7e-27 95.9 0.1 7.3e-27 94.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFP17897.1 - 1.8e-07 31.7 0.1 4.2e-07 30.5 0.1 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KFP17897.1 - 0.00087 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 KFP17897.1 - 0.0015 18.7 0.6 0.0084 16.2 0.0 2.2 2 1 0 2 2 2 1 Shikimate kinase AAA_28 PF13521.6 KFP17897.1 - 0.0025 18.1 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP17897.1 - 0.013 15.7 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFP17897.1 - 0.047 14.0 0.0 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 KFP17897.1 - 0.11 12.5 0.2 0.41 10.7 0.1 1.8 2 0 0 2 2 2 0 Adenylate kinase Cytidylate_kin2 PF13189.6 KFP17897.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KFP17897.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase DUF2353 PF09789.9 KFP17898.1 - 0.003 17.0 1.1 0.003 17.0 1.1 4.1 1 1 2 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) Nup54_57_C PF18570.1 KFP17898.1 - 0.016 14.8 3.0 0.016 14.8 3.0 2.4 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain DUF3480 PF11979.8 KFP17899.1 - 9.4e-32 110.3 0.3 1.6e-31 109.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 KFP17899.1 - 5.2e-19 68.2 15.6 1.5e-18 66.6 15.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF3480 PF11979.8 KFP17900.1 - 2.1e-108 362.4 0.0 2.4e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) DUF2181 PF10223.9 KFP17901.1 - 1.4e-84 283.3 0.1 1.6e-84 283.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Ank_2 PF12796.7 KFP17902.1 - 6.5e-26 90.7 0.2 9.4e-15 55.0 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP17902.1 - 1.9e-20 73.0 0.1 7e-07 29.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP17902.1 - 1.9e-16 59.7 0.1 4.9e-06 26.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP17902.1 - 4.2e-12 45.1 0.0 0.00017 21.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFP17902.1 - 6.8e-12 45.4 0.0 5.3e-06 26.6 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SIS PF01380.22 KFP17902.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 SIS domain DHFR_1 PF00186.19 KFP17903.1 - 3.7e-27 95.0 0.0 4.1e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase MutS_V PF00488.21 KFP17904.1 - 8.3e-73 244.4 0.2 1.8e-72 243.3 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFP17904.1 - 3e-35 122.2 0.9 1.5e-34 119.9 0.6 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KFP17904.1 - 4.8e-09 36.6 0.0 1.2e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFP17904.1 - 0.00068 19.9 0.1 0.0019 18.5 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AXE1 PF05448.12 KFP17904.1 - 0.067 11.9 0.0 0.16 10.6 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ATP-gua_Ptrans PF00217.19 KFP17907.1 - 2.5e-81 272.2 0.0 3.1e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KFP17907.1 - 3e-31 107.6 0.0 5.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain zf-CCHC PF00098.23 KFP17908.1 - 6.2e-18 64.0 26.2 1.5e-06 28.0 0.6 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KFP17908.1 - 2.2e-08 33.7 21.4 0.011 15.6 0.5 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 KFP17908.1 - 0.0084 15.8 23.6 0.25 11.1 0.6 4.4 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.6 KFP17908.1 - 0.018 14.7 0.2 0.018 14.7 0.2 3.6 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 KFP17908.1 - 0.29 11.5 0.4 0.29 11.5 0.4 3.2 2 2 2 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G Prim_Zn_Ribbon PF08273.12 KFP17908.1 - 0.43 10.9 0.3 0.43 10.9 0.3 3.3 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-CCHC_3 PF13917.6 KFP17908.1 - 0.58 10.2 12.3 4.7 7.3 0.1 3.8 3 1 1 4 4 4 0 Zinc knuckle START PF01852.19 KFP17909.1 - 2.9e-22 79.1 0.1 3.6e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 START domain 4HBT PF03061.22 KFP17910.1 - 1.1e-18 67.4 0.3 4.6e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Thioesterase superfamily SSDP PF04503.13 KFP17911.1 - 1.3e-74 252.1 75.8 2.3e-59 202.1 64.2 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP Autophagy_act_C PF03987.15 KFP17913.1 - 7.7e-20 71.2 0.6 1.5e-19 70.3 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosom_S12_S23 PF00164.25 KFP17914.1 - 9.8e-19 67.1 0.1 1.1e-18 67.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 KFP17915.1 - 9.5e-53 176.7 0.9 1.1e-52 176.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ATP-synt_S1 PF05827.12 KFP17916.1 - 2.8e-47 160.2 0.6 3.3e-47 160.0 0.6 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF1242 PF06842.12 KFP17917.1 - 3e-16 58.9 1.7 3.4e-16 58.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) WBP-1 PF11669.8 KFP17917.1 - 0.031 14.9 0.0 0.031 14.9 0.0 1.0 1 0 0 1 1 1 0 WW domain-binding protein 1 XRCC4 PF06632.12 KFP17918.1 - 4.9e-135 449.7 2.1 5.4e-135 449.6 2.1 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 ParD_antitoxin PF03693.14 KFP17918.1 - 0.0042 17.5 0.2 3.7 8.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Leu_zip PF15294.6 KFP17918.1 - 0.38 10.2 8.9 0.053 13.0 5.1 1.4 2 0 0 2 2 2 0 Leucine zipper Prefoldin_2 PF01920.20 KFP17918.1 - 6.7 6.7 9.7 3.2 7.8 0.9 2.6 2 1 1 3 3 3 0 Prefoldin subunit Xlink PF00193.17 KFP17919.1 - 1.3e-63 211.4 0.0 3.1e-34 117.2 0.0 2.3 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.17 KFP17919.1 - 6.3e-10 39.2 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP17919.1 - 5.8e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP17919.1 - 5.9e-05 23.1 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP17919.1 - 0.00049 20.4 0.0 0.0086 16.4 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP17919.1 - 0.0072 16.5 0.1 0.018 15.2 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.21 KFP17919.1 - 0.11 13.3 0.2 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Lectin C-type domain F5_F8_type_C PF00754.25 KFP17921.1 - 1.8e-61 205.8 5.1 1.3e-31 109.4 0.6 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.27 KFP17921.1 - 6e-22 77.6 37.5 8.5e-09 35.6 8.8 3.6 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 KFP17921.1 - 1.2e-09 38.4 39.0 0.00015 22.2 5.2 4.7 4 1 0 4 4 4 3 Human growth factor-like EGF EGF_2 PF07974.13 KFP17921.1 - 3.5e-05 24.1 40.3 0.082 13.3 7.4 3.7 3 0 0 3 3 3 3 EGF-like domain Vps62 PF06101.11 KFP17921.1 - 0.032 12.6 0.3 2.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 62 DUF1438 PF07270.11 KFP17921.1 - 0.11 12.6 0.1 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Pepdidase_M14_N PF18027.1 KFP17921.1 - 0.53 10.7 2.6 4 7.8 0.2 2.6 2 1 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain RVT_1 PF00078.27 KFP17922.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP17925.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KFP17926.1 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APOC4 PF15119.6 KFP17926.1 - 0.078 13.2 0.2 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein C4 RT_RNaseH_2 PF17919.1 KFP17926.1 - 0.099 12.7 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase COX7C PF02935.16 KFP17931.1 - 7.6e-17 61.3 0.7 8.2e-17 61.2 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF2834 PF11196.8 KFP17931.1 - 0.077 13.4 0.1 0.077 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) RasGAP PF00616.19 KFP17933.1 - 2.4e-27 96.0 5.0 6.6e-19 68.4 0.1 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase SH2 PF00017.24 KFP17933.1 - 1e-23 83.2 0.1 3.4e-21 75.1 0.0 2.9 2 0 0 2 2 2 2 SH2 domain PH PF00169.29 KFP17933.1 - 3.1e-18 66.2 0.2 1.9e-17 63.7 0.1 2.5 2 0 0 2 2 2 1 PH domain C2 PF00168.30 KFP17933.1 - 3.4e-12 46.6 0.1 7.3e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 KFP17933.1 - 3.5e-10 39.3 0.0 7.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP17933.1 - 5.1e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KFP17933.1 - 0.00042 20.7 1.2 0.0073 16.7 0.6 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain Cyclin_C_2 PF16899.5 KFP17934.1 - 3.5e-25 88.4 0.0 3.1e-23 82.2 0.0 2.2 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KFP17934.1 - 2.9e-09 36.8 0.0 5.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP17934.1 - 0.19 11.8 1.7 1.7 8.8 0.6 2.5 2 2 0 2 2 2 0 Cyclin, C-terminal domain Tmemb_161AB PF10268.9 KFP17936.1 - 9.2e-213 707.1 15.2 1e-212 707.0 15.2 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB SRF-TF PF00319.18 KFP17937.1 - 1.2e-19 69.5 0.5 2e-19 68.8 0.5 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.8 KFP17937.1 - 1.9e-17 63.1 1.4 3.4e-17 62.2 0.1 2.2 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat EF-hand_1 PF00036.32 KFP17938.1 - 4.2e-27 91.6 15.7 6.5e-09 34.7 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP17938.1 - 4.4e-26 91.1 11.6 3.9e-15 56.1 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP17938.1 - 1.2e-22 77.8 12.2 7.8e-06 25.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFP17938.1 - 1.7e-15 56.6 14.3 5.3e-11 42.2 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFP17938.1 - 1.7e-12 46.2 11.9 7.6e-05 22.0 0.9 4.6 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFP17938.1 - 2.2e-09 37.5 0.8 0.00014 22.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP17938.1 - 0.00017 21.5 5.4 0.069 13.1 0.2 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KFP17938.1 - 0.00044 20.2 1.0 0.77 9.7 0.0 3.8 1 1 3 4 4 4 1 Caleosin related protein HTH_40 PF14493.6 KFP17938.1 - 0.0057 17.1 2.4 0.57 10.7 0.1 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain EF-hand_14 PF17959.1 KFP17938.1 - 0.007 16.7 3.0 0.25 11.7 0.3 2.5 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KFP17938.1 - 0.013 15.8 5.6 0.26 11.6 1.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.6 KFP17938.1 - 0.021 14.7 0.8 6.2 6.7 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain SurA_N_3 PF13624.6 KFP17938.1 - 0.034 13.9 4.0 1.2 8.9 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain UBA_2 PF08587.11 KFP17938.1 - 0.045 13.9 0.1 2.4 8.4 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) MgtE_N PF03448.17 KFP17938.1 - 0.11 13.1 0.7 0.11 13.1 0.7 2.5 1 1 2 3 3 3 0 MgtE intracellular N domain YolD PF08863.10 KFP17938.1 - 2.1 8.5 5.9 3.8 7.6 1.9 2.7 2 1 1 3 3 3 0 YolD-like protein RNA_pol_3_Rpc31 PF11705.8 KFP17940.1 - 1.2e-32 114.0 25.2 1.5e-32 113.7 25.2 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KFP17940.1 - 0.013 14.8 22.9 0.018 14.4 22.9 1.3 1 0 0 1 1 1 0 BUD22 Protocadherin PF08374.11 KFP17940.1 - 0.1 12.5 5.5 0.13 12.2 5.5 1.2 1 0 0 1 1 1 0 Protocadherin DUF5427 PF10310.9 KFP17940.1 - 0.61 9.0 14.6 0.73 8.7 14.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ALMT PF11744.8 KFP17940.1 - 1.2 7.9 5.2 1.4 7.6 5.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5094 PF17015.5 KFP17940.1 - 1.2 9.2 15.1 2 8.5 15.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) PA26 PF04636.13 KFP17940.1 - 2.5 6.9 8.3 3.2 6.6 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rgp1 PF08737.10 KFP17940.1 - 2.8 7.0 7.2 3.2 6.8 7.2 1.1 1 0 0 1 1 1 0 Rgp1 DNA_pol_phi PF04931.13 KFP17940.1 - 4 5.4 22.2 4.5 5.2 22.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 KFP17940.1 - 4.8 4.8 10.4 5.9 4.5 10.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Neur_chan_memb PF02932.16 KFP17940.1 - 6.5 6.7 6.1 7.9 6.5 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 KFP17940.1 - 6.7 5.4 12.0 7.8 5.1 12.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 KFP17940.1 - 8.9 5.4 9.8 10 5.2 9.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter YqhR PF11085.8 KFP17941.1 - 0.023 14.6 0.2 0.031 14.2 0.2 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF4199 PF13858.6 KFP17941.1 - 0.095 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PINIT PF14324.6 KFP17942.1 - 3e-39 134.7 0.2 8.8e-39 133.2 0.2 1.9 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFP17942.1 - 7.1e-21 73.7 5.0 1.4e-20 72.8 5.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFP17942.1 - 0.00018 21.2 1.5 0.00048 19.9 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KFP17942.1 - 0.69 9.8 4.9 2.6 8.0 4.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MRNIP PF15749.5 KFP17942.1 - 2.2 9.0 8.4 0.39 11.5 0.3 2.3 1 1 0 2 2 2 0 MRN-interacting protein CLN6 PF15156.6 KFP17943.1 - 8.1e-146 484.6 17.4 9e-146 484.5 17.4 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 CcmD PF04995.14 KFP17943.1 - 0.34 11.0 2.6 36 4.6 2.4 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Herpes_LMP1 PF05297.11 KFP17943.1 - 0.68 9.1 4.8 1.2 8.2 4.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Saf_2TM PF18303.1 KFP17943.1 - 1.4 8.5 4.9 0.65 9.6 2.6 1.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Ank_2 PF12796.7 KFP17944.1 - 4.2e-39 133.0 8.3 4.6e-19 68.8 0.8 4.8 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP17944.1 - 1.1e-34 118.3 6.5 6.4e-12 45.7 0.1 7.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KFP17944.1 - 1.7e-32 110.4 16.1 8.3e-06 26.0 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFP17944.1 - 8.7e-32 105.6 11.7 4e-05 23.7 0.0 8.7 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP17944.1 - 1.5e-28 98.5 15.0 3e-06 27.4 0.1 7.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Integrin_alpha2 PF08441.12 KFP17945.1 - 1.3e-44 152.9 0.0 2e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.28 KFP17945.1 - 1.9e-37 129.2 0.0 3e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFP17945.1 - 4.9e-15 55.3 10.6 6.8e-07 29.3 0.3 4.2 4 0 0 4 4 4 2 FG-GAP repeat VWA_2 PF13519.6 KFP17945.1 - 4.4e-13 49.8 0.0 1.3e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFP17945.1 - 2e-08 34.7 0.3 3.6e-05 24.3 0.1 3.0 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFP17945.1 - 9.2e-08 32.2 3.4 0.15 12.4 0.0 4.3 5 0 0 5 5 5 3 FG-GAP repeat LYRIC PF15686.5 KFP17945.1 - 0.31 10.5 0.1 0.49 9.9 0.1 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family IPK PF03770.16 KFP17950.1 - 2.6e-68 229.8 0.1 4.7e-68 228.9 0.1 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase TMP-TENI PF02581.17 KFP17950.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase zf-CDGSH PF09360.10 KFP17951.1 - 7e-10 39.0 0.3 1.2e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 KFP17951.1 - 9e-08 32.0 0.2 1.2e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus CHDNT PF08073.12 KFP17951.1 - 0.08 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain UQ_con PF00179.26 KFP17952.1 - 7.8e-50 168.2 0.0 8.6e-50 168.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP17952.1 - 0.0016 18.8 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP17952.1 - 0.0075 16.0 0.0 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP17952.1 - 0.076 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain HMG_box PF00505.19 KFP17953.1 - 1.5e-19 70.2 12.5 1e-09 38.7 1.1 3.0 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP17953.1 - 5.9e-13 49.2 10.3 3e-09 37.3 1.0 2.9 2 1 0 2 2 2 2 HMG-box domain DUF4055 PF13264.6 KFP17953.1 - 0.22 11.7 5.3 1.3 9.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Oxidored-like PF09791.9 KFP17953.1 - 0.24 11.1 1.8 14 5.4 0.2 2.6 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal Endonuc_Holl PF10107.9 KFP17953.1 - 0.61 9.9 13.7 0.8 9.5 2.3 2.4 2 1 1 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase PSI_PsaF PF02507.15 KFP17953.1 - 0.75 9.6 3.4 0.36 10.7 0.3 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III DUF3719 PF12516.8 KFP17954.1 - 5.2e-22 77.3 0.7 7.7e-21 73.6 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) SGT1 PF07093.11 KFP17955.1 - 8.9e-196 651.8 1.2 1e-195 651.6 1.2 1.0 1 0 0 1 1 1 1 SGT1 protein zf-RING_14 PF17978.1 KFP17955.1 - 0.097 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YL1 PF05764.13 KFP17955.1 - 0.87 9.7 11.7 1.4 9.0 11.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PI3K_1B_p101 PF10486.9 KFP17955.1 - 3 5.5 8.7 3.9 5.1 8.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit P4Ha_N PF08336.11 KFP17956.1 - 1.2e-40 138.7 1.3 1.5e-40 138.4 0.1 1.8 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFP17956.1 - 4.8e-16 59.4 0.0 1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP17956.1 - 1.2e-08 35.4 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KFP17956.1 - 0.0013 18.8 0.5 0.013 15.6 0.5 2.5 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KFP17956.1 - 0.05 13.7 0.8 0.35 11.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP17956.1 - 0.073 13.9 0.2 0.3 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.6 KFP17956.1 - 0.081 12.6 1.8 0.18 11.5 1.8 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein Zona_pellucida PF00100.23 KFP17957.1 - 3.2e-48 164.8 0.1 1.5e-47 162.6 0.0 1.9 2 0 0 2 2 2 1 Zona pellucida-like domain FXa_inhibition PF14670.6 KFP17957.1 - 3.4e-17 62.4 30.3 1.6e-10 41.0 11.2 4.6 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP17957.1 - 8.3e-07 28.8 18.5 0.0028 17.5 0.7 4.2 3 0 0 3 3 3 3 Complement Clr-like EGF-like RTP801_C PF07809.11 KFP17960.1 - 2.1e-39 134.1 0.0 2.6e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 RTP801 C-terminal region ANAPC16 PF17256.2 KFP17961.1 - 6.3e-57 189.9 0.1 7.5e-57 189.7 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 16 DUF2110 PF09883.9 KFP17961.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) AKAP7_NLS PF10469.9 KFP17962.1 - 1.3e-58 198.3 0.1 1.6e-58 198.1 0.1 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 KFP17962.1 - 2e-10 40.3 0.9 2e-10 40.3 0.9 1.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 KFP17962.1 - 0.023 14.5 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 KH domain HVSL PF09749.9 KFP17962.1 - 0.058 12.9 0.1 0.079 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Arf PF00025.21 KFP17963.1 - 4.5e-61 205.3 0.0 5e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP17963.1 - 4e-10 39.4 0.0 4.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP17963.1 - 1e-09 38.1 0.1 2.4e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KFP17963.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP17963.1 - 4e-08 33.0 0.0 4.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP17963.1 - 8.2e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP17963.1 - 0.00048 19.7 0.0 0.0055 16.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Metalloenzyme PF01676.18 KFP17963.1 - 0.0045 16.4 0.0 0.046 13.1 0.0 1.9 1 1 1 2 2 2 1 Metalloenzyme superfamily Gtr1_RagA PF04670.12 KFP17963.1 - 0.0053 16.1 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pyrophosphatase PF00719.19 KFP17964.1 - 1.2e-61 207.2 0.5 1.5e-61 206.9 0.5 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase LRR_8 PF13855.6 KFP17965.1 - 8.4e-17 60.7 3.2 2.8e-08 33.4 4.1 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFP17965.1 - 2.9e-13 49.8 2.8 0.00032 21.0 1.6 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP17965.1 - 2.7e-08 33.3 3.8 0.56 11.0 0.2 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP17965.1 - 1.5e-05 24.7 5.5 14 6.1 0.1 5.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_9 PF14580.6 KFP17965.1 - 3.8e-05 23.3 0.4 0.00013 21.6 0.4 1.6 1 1 0 1 1 1 1 Leucine-rich repeat PTPlike_phytase PF14566.6 KFP17966.1 - 3.8e-78 261.0 0.0 3.3e-41 141.0 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP17966.1 - 0.00082 19.0 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase HTH_48 PF17906.1 KFP17966.1 - 0.052 13.7 0.1 0.19 11.9 0.1 2.0 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Vitellogenin_N PF01347.22 KFP17967.1 - 1.1e-15 57.1 0.2 1.5e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.11 KFP17967.1 - 1.3e-05 24.6 0.2 0.00015 21.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1943) Phage_int_SAM_1 PF02899.17 KFP17967.1 - 0.37 11.1 1.5 29 5.0 0.1 2.8 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CBM_21 PF03370.13 KFP17968.1 - 1.9e-29 102.1 0.1 4.5e-29 100.9 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP17968.1 - 1.2e-07 32.2 0.1 4.2e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MAPEG PF01124.18 KFP17969.1 - 2.8e-14 53.1 5.3 2.9e-14 53.1 4.5 1.4 1 1 0 1 1 1 1 MAPEG family dNK PF01712.19 KFP17970.1 - 8.8e-65 218.4 1.6 9.7e-65 218.2 1.6 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFP17970.1 - 7.8e-05 23.2 0.2 0.00074 20.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP17970.1 - 0.0021 18.2 0.0 0.013 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFP17970.1 - 0.0081 15.9 0.0 0.047 13.4 0.1 2.1 2 0 0 2 2 2 1 Thymidylate kinase RRM_1 PF00076.22 KFP17971.1 - 4.2e-25 87.4 0.0 4.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.12 KFP17971.1 - 2.3e-13 49.9 14.6 1.1e-12 47.7 14.6 2.2 1 1 0 1 1 1 1 RNPHF zinc finger RRM_3 PF08777.11 KFP17971.1 - 0.00062 19.8 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 KFP17971.1 - 0.21 11.7 0.1 0.55 10.3 0.1 1.7 1 0 0 1 1 1 0 Limkain b1 RUN PF02759.19 KFP17972.1 - 2.1e-25 89.2 0.0 5.6e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 RUN domain SlyX PF04102.12 KFP17972.1 - 3.7 8.3 11.3 6.6 7.4 0.4 2.9 2 0 0 2 2 2 0 SlyX Med4 PF10018.9 KFP17972.1 - 4.8 6.8 11.3 3.2 7.4 3.3 2.5 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Pep_M12B_propep PF01562.19 KFP17974.1 - 1.3e-33 116.2 0.0 4.4e-33 114.5 0.0 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFP17974.1 - 9.2e-25 86.9 0.0 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP17974.1 - 1.2e-22 79.9 58.9 2.3e-10 40.5 6.9 6.0 6 1 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.19 KFP17974.1 - 2.8e-18 66.6 0.0 5.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP17974.1 - 9.5e-18 64.5 16.5 2e-17 63.5 5.9 5.2 6 1 1 7 7 3 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFP17974.1 - 3.2e-14 53.5 0.1 7.6e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP17974.1 - 1.2e-10 42.0 0.1 2.6e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP17974.1 - 1.7e-09 37.8 0.2 3.7e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP17974.1 - 2.9e-06 27.1 0.1 5.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFP17974.1 - 0.0013 18.5 0.3 0.0031 17.4 0.1 1.7 2 0 0 2 2 2 1 Matrixin PLAC PF08686.11 KFP17974.1 - 0.015 16.0 7.5 0.015 16.0 7.5 3.6 4 0 0 4 4 3 0 PLAC (protease and lacunin) domain DUF4953 PF16313.5 KFP17974.1 - 0.099 11.8 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Exo_endo_phos PF03372.23 KFP17976.1 - 7.8e-21 74.7 0.0 3.3e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFP17976.1 - 4.1e-11 42.5 12.2 9.2e-11 41.3 8.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP17976.1 - 2.9e-10 40.2 17.5 2.5e-07 30.9 1.5 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP17976.1 - 0.0058 17.0 16.1 12 6.9 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP17976.1 - 0.21 11.8 17.4 1.2 9.4 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat SIS PF01380.22 KFP17977.1 - 2e-67 225.0 0.0 1.6e-36 125.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFP17977.1 - 2.7e-16 60.0 0.0 6.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFP17977.1 - 1.6e-13 50.7 0.0 6e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFP17977.1 - 3.8e-05 22.7 0.0 6.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFP17977.1 - 7.1e-05 21.7 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KFP17977.1 - 0.07 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 SIS domain Pkinase PF00069.25 KFP17978.1 - 5.7e-64 216.0 0.0 7.1e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17978.1 - 1.5e-29 103.1 0.1 2e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP17978.1 - 1.8e-06 27.5 0.3 2.9e-06 26.8 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP17978.1 - 4.7e-05 22.8 0.1 0.001 18.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP17978.1 - 0.00049 20.1 0.3 0.00091 19.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP17978.1 - 0.00054 19.6 0.2 0.00093 18.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 KFP17978.1 - 0.071 12.7 0.3 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RasGEF PF00617.19 KFP17979.1 - 2.1e-52 177.9 0.2 3.6e-52 177.1 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFP17979.1 - 0.00051 20.2 0.0 0.17 12.1 0.0 2.8 1 1 1 2 2 2 2 RasGEF N-terminal motif Pkinase PF00069.25 KFP17980.1 - 4e-53 180.5 0.5 5.5e-53 180.0 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP17980.1 - 1.6e-25 89.9 1.3 3.9e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Aminotran_3 PF00202.21 KFP17981.1 - 1.8e-82 277.2 0.0 2.2e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III RRM_1 PF00076.22 KFP17982.1 - 4.7e-34 116.0 0.3 1e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP17982.1 - 1.2e-17 63.8 0.5 8.8e-09 35.4 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP17982.1 - 4.4e-07 29.8 0.0 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP17982.1 - 2.8e-05 24.1 0.1 0.1 12.7 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif NID PF07292.13 KFP17982.1 - 0.0062 17.2 0.3 0.56 10.9 0.2 2.4 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) Peptidase_M16_C PF05193.21 KFP17982.1 - 0.026 14.6 0.1 0.062 13.3 0.1 1.6 2 0 0 2 2 2 0 Peptidase M16 inactive domain FXMRP1_C_core PF12235.8 KFP17982.1 - 0.34 11.6 5.0 0.73 10.5 5.0 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal NDK PF00334.19 KFP17983.1 - 9.6e-37 126.0 0.0 1.2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 KFP17983.1 - 3.9e-18 64.8 0.7 6.1e-18 64.2 0.7 1.3 1 0 0 1 1 1 1 Dpy-30 motif wnt PF00110.19 KFP17984.1 - 4.6e-90 302.3 25.1 5.6e-90 302.1 25.1 1.0 1 0 0 1 1 1 1 wnt family Thymosin PF01290.20 KFP17985.1 - 6.3e-21 73.8 10.0 6.8e-21 73.7 10.0 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.20 KFP17985.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 WH2 motif DUF4522 PF15022.6 KFP17985.1 - 0.022 15.0 0.3 0.023 14.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) RhoGAP PF00620.27 KFP17986.1 - 8.7e-37 126.3 1.8 5.7e-36 123.6 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.8 KFP17986.1 - 0.00034 20.3 9.5 0.00034 20.3 9.5 3.9 3 2 1 4 4 4 2 DNA replication and checkpoint protein IZUMO PF15005.6 KFP17986.1 - 0.065 13.8 6.7 3.4 8.2 0.5 3.7 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated DUF1732 PF08340.11 KFP17986.1 - 0.083 12.9 0.7 0.51 10.4 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) PilJ PF13675.6 KFP17986.1 - 0.18 11.8 4.9 1.5 8.9 1.1 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term GAS PF13851.6 KFP17986.1 - 4.3 6.6 21.0 0.67 9.3 2.8 3.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Cytochrom_B562 PF07361.11 KFP17986.1 - 6.6 7.4 10.0 0.4 11.3 0.7 3.2 3 1 0 3 3 3 0 Cytochrome b562 I-set PF07679.16 KFP17987.1 - 2.5e-40 136.4 0.0 2.9e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP17987.1 - 1e-27 96.5 0.0 2.2e-13 50.6 0.1 3.0 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP17987.1 - 1.9e-16 60.1 0.3 1.3e-06 28.6 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP17987.1 - 2.4e-13 50.0 0.0 6.9e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFP17987.1 - 2.3e-08 34.2 0.0 0.0042 17.2 0.0 3.6 2 1 0 2 2 2 2 Immunoglobulin V-set domain Herpes_gE PF02480.16 KFP17987.1 - 0.02 13.7 0.0 0.2 10.4 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Ig_6 PF18452.1 KFP17987.1 - 0.026 14.1 0.0 0.085 12.4 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFP17987.1 - 0.041 13.9 0.0 3.8 7.7 0.0 3.0 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFP17988.1 - 1.1e-18 67.1 0.0 1.6e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP17988.1 - 9.8e-09 35.7 0.0 2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP17988.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP17988.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP17988.1 - 0.0015 18.6 0.0 0.01 16.0 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain 7tm_1 PF00001.21 KFP17989.1 - 4.3e-52 177.1 21.0 4.3e-52 177.1 21.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP17989.1 - 1.2e-07 31.3 20.0 3.3e-07 29.9 20.0 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP17989.1 - 1.2e-06 28.4 17.8 1.2e-06 28.4 17.8 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Peptidase_A22B PF04258.13 KFP17989.1 - 7.4 6.0 18.3 0.032 13.8 7.2 2.2 2 1 0 2 2 2 0 Signal peptide peptidase Kelch_1 PF01344.25 KFP17990.1 - 2.3e-68 225.6 10.2 4.6e-16 58.1 0.3 5.2 5 0 0 5 5 5 5 Kelch motif BACK PF07707.15 KFP17990.1 - 1.7e-36 124.4 1.0 1.7e-36 124.4 1.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP17990.1 - 2.5e-32 111.4 0.8 5.7e-32 110.2 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP17990.1 - 5.2e-31 105.9 0.2 3.1e-05 24.1 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KFP17990.1 - 3.7e-25 87.7 7.8 6.1e-05 23.2 0.2 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP17990.1 - 2e-23 81.4 1.6 7e-05 22.6 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP17990.1 - 1.1e-18 67.0 2.1 0.00017 21.5 0.0 5.3 3 1 2 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP17990.1 - 0.00068 19.6 7.7 2.9 8.0 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Skp1_POZ PF03931.15 KFP17990.1 - 0.0053 16.9 0.2 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF3342 PF11822.8 KFP17990.1 - 0.12 12.6 0.8 0.83 9.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3342) DPPIV_N PF00930.21 KFP17993.1 - 4.6e-106 354.5 0.1 6.1e-106 354.2 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP17993.1 - 1.1e-49 168.9 0.0 1.6e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KFP17993.1 - 1.2e-06 28.2 0.0 4.1e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 KFP17993.1 - 9.6e-05 22.2 0.1 1.6 8.7 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 KFP17993.1 - 9.7e-05 21.7 0.3 0.18 11.0 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Pecanex_C PF05041.15 KFP17993.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Abhydrolase_3 PF07859.13 KFP17993.1 - 0.021 14.7 0.0 0.39 10.5 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KFP17993.1 - 0.022 14.7 0.8 0.11 12.5 0.3 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KFP17993.1 - 0.031 13.9 0.0 1.7 8.2 0.0 2.8 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 KFP17993.1 - 0.042 13.0 0.2 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 KFP17993.1 - 0.082 12.7 0.2 0.082 12.7 0.2 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Actin PF00022.19 KFP17996.1 - 3.1e-86 289.6 0.0 2.2e-52 178.1 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFP17996.1 - 3.3e-05 22.9 0.0 0.052 12.4 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFP17996.1 - 0.018 15.4 0.0 0.043 14.2 0.0 1.8 2 1 0 2 2 2 0 Cell division protein FtsA Robl_LC7 PF03259.17 KFP17996.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain EamA PF00892.20 KFP17997.1 - 1.4e-10 41.5 42.0 3.6e-06 27.2 5.9 3.2 3 0 0 3 3 3 3 EamA-like transporter family BAGE PF08180.11 KFP17997.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 B melanoma antigen family MHYT PF03707.16 KFP17997.1 - 2.1 8.6 7.7 0.88 9.8 0.1 3.4 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat 7tm_1 PF00001.21 KFP17998.1 - 1.5e-34 119.6 11.6 1.5e-34 119.6 11.6 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP17998.1 - 4.3e-05 23.4 4.1 0.003 17.3 1.1 2.4 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP17998.1 - 0.00041 19.8 1.1 0.00041 19.8 1.1 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP17998.1 - 0.0028 17.3 3.9 0.0028 17.3 3.9 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPAR_LY6_2 PF16975.5 KFP17999.1 - 0.0014 18.8 9.8 0.0019 18.4 9.8 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 NCKAP5 PF15246.6 KFP18000.1 - 3.9e-123 411.0 23.5 3.9e-123 411.0 23.5 4.6 5 1 1 6 6 6 1 Nck-associated protein 5, Peripheral clock protein Neur_chan_LBD PF02931.23 KFP18001.1 - 6.5e-50 169.6 0.0 9.7e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP18001.1 - 5.4e-38 131.4 7.8 7.7e-31 108.0 5.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CytochromB561_N PF09786.9 KFP18001.1 - 0.067 12.2 2.0 0.092 11.7 2.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF5522 PF17653.1 KFP18001.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Neur_chan_memb PF02932.16 KFP18002.1 - 3.7e-40 138.5 3.1 1.6e-35 123.3 0.7 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP18002.1 - 4.4e-37 127.6 1.8 5.6e-37 127.3 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Glucosamine_iso PF01182.20 KFP18005.1 - 2e-20 73.6 0.0 2.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GTP_EFTU PF00009.27 KFP18007.1 - 3.7e-54 183.2 0.1 5.3e-54 182.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFP18007.1 - 2.3e-47 159.6 0.6 1.2e-46 157.3 0.6 2.3 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFP18007.1 - 9.4e-21 73.7 0.0 3.2e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFP18007.1 - 1.5e-07 31.7 1.2 4.5e-07 30.2 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 KFP18007.1 - 9.2e-07 28.6 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 KFP18007.1 - 5.9e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KFP18007.1 - 1.1e-05 25.4 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KFP18007.1 - 2.6e-05 24.2 0.0 9.3e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KFP18007.1 - 0.0023 17.4 0.0 0.0062 16.0 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KFP18007.1 - 0.0041 17.1 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Septin PF00735.18 KFP18007.1 - 0.0089 15.3 0.8 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 KFP18007.1 - 0.026 14.1 0.3 0.076 12.5 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PhoLip_ATPase_C PF16212.5 KFP18012.1 - 3.1e-86 289.2 19.8 3.1e-86 289.2 19.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP18012.1 - 8.1e-26 89.5 4.3 2.3e-25 88.1 4.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP18012.1 - 2.1e-13 51.1 0.0 1.9e-05 25.0 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP18012.1 - 5.5e-13 48.8 0.0 7.3e-12 45.2 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP18012.1 - 2.5e-11 43.4 0.0 1e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP18012.1 - 0.00019 21.3 0.3 0.012 15.4 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Shisa PF13908.6 KFP18014.1 - 6.3e-22 78.7 1.2 7.3e-22 78.5 1.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator BEN PF10523.9 KFP18015.1 - 2.2e-15 56.6 0.0 4.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 BEN domain bZIP_1 PF00170.21 KFP18015.1 - 0.0048 17.0 0.2 0.013 15.5 0.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Uds1 PF15456.6 KFP18015.1 - 0.015 15.5 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Cep57_CLD_2 PF14197.6 KFP18015.1 - 0.026 14.6 0.6 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 KFP18015.1 - 0.027 14.4 1.6 0.027 14.4 1.6 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 KFP18015.1 - 0.043 13.9 1.9 0.12 12.5 1.9 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.15 KFP18015.1 - 0.043 13.9 3.9 0.097 12.8 3.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Herpes_BLRF2 PF05812.12 KFP18015.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Cation_efflux PF01545.21 KFP18016.1 - 1.6e-31 109.6 7.7 2e-31 109.3 7.7 1.1 1 0 0 1 1 1 1 Cation efflux family XPA_C PF05181.12 KFP18016.1 - 0.00014 21.7 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus ZT_dimer PF16916.5 KFP18016.1 - 0.0028 17.7 1.1 0.099 12.8 0.1 3.0 2 1 1 3 3 3 1 Dimerisation domain of Zinc Transporter Ion_trans_N PF08412.10 KFP18016.1 - 0.033 13.8 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal Peptidase_M30 PF10460.9 KFP18016.1 - 0.04 12.9 0.1 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase M30 P2 PF07194.11 KFP18016.1 - 0.064 13.3 0.1 0.3 11.2 0.2 2.1 2 0 0 2 2 2 0 P2 response regulator binding domain Deltameth_res PF16020.5 KFP18016.1 - 0.096 12.6 0.4 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Deltamethrin resistance UPF0121 PF03661.13 KFP18017.1 - 9.8e-94 313.3 17.9 1.1e-93 313.1 17.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Homeodomain PF00046.29 KFP18018.1 - 5.9e-14 51.7 0.5 9.2e-14 51.0 0.5 1.3 1 0 0 1 1 1 1 Homeodomain Myb_DNA-bind_3 PF12776.7 KFP18018.1 - 0.026 15.5 0.0 1.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4757 PF15949.5 KFP18019.1 - 5.7e-65 219.0 9.6 5.7e-65 219.0 9.6 4.2 2 1 1 4 4 4 1 Domain of unknown function (DUF4757) LIM PF00412.22 KFP18019.1 - 2e-07 31.1 0.3 4.8e-07 29.9 0.3 1.7 1 0 0 1 1 1 1 LIM domain Peptidase_C12 PF01088.21 KFP18020.1 - 1.3e-45 155.7 1.4 1.5e-45 155.6 1.4 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ObR_Ig PF18589.1 KFP18020.1 - 0.033 14.6 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Obesity receptor immunoglobulin like domain PID PF00640.23 KFP18021.1 - 6.2e-47 159.2 0.0 7.6e-34 116.7 0.0 2.4 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.26 KFP18021.1 - 1.2e-06 28.5 1.5 2.8e-06 27.3 1.5 1.7 1 0 0 1 1 1 1 WW domain PTB PF08416.13 KFP18021.1 - 4.4e-06 26.9 0.0 0.00099 19.3 0.0 2.6 2 0 0 2 2 2 2 Phosphotyrosine-binding domain CDO_I PF05995.12 KFP18021.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I Methyltr_RsmB-F PF01189.17 KFP18022.1 - 3.1e-08 33.5 0.1 1.8e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Tox-PL-2 PF15643.6 KFP18022.1 - 0.036 14.2 0.1 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Papain fold toxin 2 Neur_chan_LBD PF02931.23 KFP18023.1 - 6.2e-68 228.5 1.9 8.2e-68 228.1 1.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP18023.1 - 2e-48 165.5 0.1 2.7e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 KFP18026.1 - 4e-43 146.8 0.0 4.6e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP18026.1 - 1.6e-22 80.0 0.0 2.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP18026.1 - 2e-06 27.4 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP18026.1 - 0.032 14.3 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KFP18026.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KFP18026.1 - 0.1 12.0 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Cnd1 PF12717.7 KFP18027.1 - 0.0016 18.5 9.0 1 9.4 0.1 5.7 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP18027.1 - 0.028 14.7 1.8 6.5 7.3 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 KFP18027.1 - 0.51 10.9 3.9 40 4.8 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat UQ_con PF00179.26 KFP18028.1 - 3.5e-42 143.4 0.1 4.3e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 KFP18028.1 - 4e-11 42.6 0.0 9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 KFP18028.1 - 2e-05 24.3 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFP18028.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UBA_3 PF09288.10 KFP18028.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF2615 PF11027.8 KFP18029.1 - 8.7e-42 141.6 0.0 1e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) UDPG_MGDP_dh_N PF03721.14 KFP18030.1 - 2e-62 210.1 0.0 5e-62 208.8 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KFP18030.1 - 1.2e-36 125.3 0.0 3.4e-35 120.7 0.0 2.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KFP18030.1 - 1.7e-33 114.7 0.0 6.5e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 KFP18030.1 - 0.0025 17.7 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KFP18030.1 - 0.012 15.6 0.0 4.5 7.4 0.0 3.7 2 2 2 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFP18030.1 - 0.034 14.7 0.0 5.7 7.6 0.0 3.3 4 2 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFP18030.1 - 0.037 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KFP18030.1 - 0.085 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFP18030.1 - 0.16 11.6 0.0 0.8 9.3 0.0 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA LIAS_N PF16881.5 KFP18031.1 - 1.1e-43 148.1 0.3 2e-43 147.2 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFP18031.1 - 1.8e-16 61.0 0.0 2.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_L6 PF00347.23 KFP18032.1 - 1.6e-33 115.2 1.1 1.6e-16 60.7 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 RFC1 PF08519.12 KFP18033.1 - 6.2e-60 201.9 0.0 1.7e-59 200.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFP18033.1 - 9.2e-17 61.2 0.0 3.7e-16 59.3 0.0 2.1 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFP18033.1 - 6.1e-15 55.8 0.0 1.4e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 KFP18033.1 - 2.2e-07 30.7 0.1 6.5e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 twin BRCT domain Rad17 PF03215.15 KFP18033.1 - 6.5e-05 22.9 0.4 0.00073 19.5 0.4 2.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KFP18033.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFP18033.1 - 0.00034 20.6 0.1 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP18033.1 - 0.00049 20.4 0.0 0.0021 18.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP18033.1 - 0.00054 20.4 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KFP18033.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFP18033.1 - 0.0021 18.4 0.0 0.012 16.0 0.0 2.4 2 1 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 KFP18033.1 - 0.0022 18.2 0.0 0.0062 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFP18033.1 - 0.0052 17.3 0.1 0.022 15.3 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFP18033.1 - 0.0093 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 KFP18033.1 - 0.014 15.8 1.0 0.043 14.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain BRCT_2 PF16589.5 KFP18033.1 - 0.014 15.8 0.0 0.048 14.1 0.0 1.9 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AAA_30 PF13604.6 KFP18033.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFP18033.1 - 0.039 13.8 0.2 0.16 11.9 0.1 2.1 1 1 1 2 2 2 0 NTPase WD40_3 PF15911.5 KFP18034.1 - 8.9e-29 99.3 1.2 5.4e-28 96.8 0.0 3.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Clathrin PF00637.20 KFP18034.1 - 1.1e-12 48.1 3.9 0.00031 20.6 0.1 4.9 2 1 3 5 5 5 4 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KFP18034.1 - 6.3e-11 42.4 0.5 0.058 13.7 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFP18034.1 - 3.4e-07 29.7 3.1 0.32 10.0 0.0 3.9 4 1 0 4 4 4 3 Coatomer WD associated region TPR_8 PF13181.6 KFP18034.1 - 0.0013 18.8 10.6 1.5 9.2 0.2 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat WD40 PF00400.32 KFP18034.1 - 0.0018 19.0 6.9 7 7.7 0.1 6.2 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 KFP18034.1 - 0.0026 17.7 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TPR_14 PF13428.6 KFP18034.1 - 0.0059 17.3 8.2 12 7.0 0.2 7.2 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP18034.1 - 0.023 14.9 7.3 5.2 7.4 1.4 4.9 2 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Mcl1_mid PF12341.8 KFP18034.1 - 0.044 13.1 0.0 0.42 9.9 0.0 2.5 2 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region TPR_12 PF13424.6 KFP18034.1 - 0.047 14.0 6.2 29 5.0 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 KFP18034.1 - 0.19 11.1 8.7 0.11 11.9 2.5 2.8 1 1 2 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KFP18034.1 - 0.26 11.5 21.1 4.3 7.7 0.4 7.3 7 0 0 7 7 6 0 Tetratricopeptide repeat DZR PF12773.7 KFP18034.1 - 1 9.5 11.6 7.9 6.6 10.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon TPR_7 PF13176.6 KFP18034.1 - 1.6 8.9 11.8 6.5 7.0 0.2 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat TMEM156 PF15106.6 KFP18035.1 - 5e-84 281.2 15.3 6.3e-84 280.9 15.3 1.0 1 0 0 1 1 1 1 TMEM156 protein family DUF719 PF05334.13 KFP18036.1 - 2.8e-65 220.1 3.4 2.8e-65 220.1 3.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF719) TetR_C_24 PF17932.1 KFP18036.1 - 0.031 14.5 0.1 0.12 12.7 0.1 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2732 PF10809.8 KFP18036.1 - 0.97 9.3 4.5 6.8 6.6 4.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2732) TIR PF01582.20 KFP18037.1 - 1.2e-24 87.0 0.0 2.6e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 KFP18037.1 - 4.2e-19 68.1 12.1 2.7e-09 36.6 1.2 4.5 3 1 1 4 4 4 3 Leucine rich repeat TIR_2 PF13676.6 KFP18037.1 - 2.4e-15 57.2 0.0 6.9e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.7 KFP18037.1 - 2.8e-15 56.2 26.8 1.7e-06 28.3 0.2 6.6 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP18037.1 - 1.6e-05 24.8 14.2 7.6 7.5 0.7 8.0 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 KFP18037.1 - 8e-05 22.2 0.3 0.11 12.0 0.0 2.7 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFP18037.1 - 0.00028 20.7 17.9 0.75 10.0 0.1 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRRCT PF01463.24 KFP18037.1 - 0.00093 19.6 0.0 0.0047 17.4 0.0 2.3 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Tim29 PF10171.9 KFP18037.1 - 0.061 12.8 0.6 0.13 11.8 0.6 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 TIR PF01582.20 KFP18038.1 - 1e-24 87.3 0.1 2.1e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.6 KFP18038.1 - 2.9e-19 68.6 12.8 2.1e-09 37.0 1.3 4.6 2 2 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP18038.1 - 5.4e-16 58.4 25.3 1.3e-06 28.6 0.2 6.3 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KFP18038.1 - 9.1e-11 42.4 0.0 4.2e-10 40.3 0.0 2.1 3 0 0 3 3 3 1 TIR domain LRR_6 PF13516.6 KFP18038.1 - 1.6e-09 37.0 8.3 0.6 10.3 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KFP18038.1 - 3.1e-05 23.9 16.9 5.9 7.9 0.7 7.7 5 2 1 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP18038.1 - 0.0011 18.5 1.4 0.095 12.2 0.1 2.6 1 1 0 2 2 2 1 Leucine-rich repeat LRRCT PF01463.24 KFP18038.1 - 0.0012 19.3 0.1 0.0061 17.0 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain zf-C2H2 PF00096.26 KFP18039.1 - 2.5e-16 59.1 22.9 2e-06 27.9 2.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP18039.1 - 9.8e-13 47.9 8.7 3.1e-09 36.8 1.0 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP18039.1 - 1.5e-08 34.8 20.1 0.0022 18.7 1.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFP18039.1 - 0.041 14.3 2.7 7.5 7.1 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP18039.1 - 0.12 12.7 3.7 8.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP18039.1 - 0.12 12.4 9.4 0.38 10.8 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFP18039.1 - 0.65 10.1 4.3 3.7 7.7 2.9 2.1 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 KFP18039.1 - 1.2 9.9 8.0 4.6 7.9 0.7 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain RVT_1 PF00078.27 KFP18040.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 KFP18042.1 - 8.5e-53 179.2 0.7 3.1e-52 177.3 0.7 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.8 KFP18042.1 - 5.2e-22 77.9 1.8 5.2e-22 77.9 1.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) PID PF00640.23 KFP18042.1 - 1.2e-12 48.1 6.0 9.1e-09 35.5 0.6 3.2 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) RnlB_antitoxin PF15933.5 KFP18042.1 - 0.25 11.7 2.0 0.79 10.1 2.0 1.9 1 0 0 1 1 1 0 Antitoxin to bacterial toxin RNase LS or RnlA FANCI_S1-cap PF14674.6 KFP18042.1 - 5.3 7.2 6.1 5.7 7.1 0.2 3.0 2 0 0 2 2 2 0 FANCI solenoid 1 cap PGM_PMM_I PF02878.16 KFP18045.1 - 6.5e-37 126.3 0.0 1.3e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KFP18045.1 - 2.2e-24 86.0 0.0 6.9e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KFP18045.1 - 2.5e-12 47.0 0.2 1.1e-11 44.9 0.0 2.3 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KFP18045.1 - 9.1e-06 25.8 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RELT PF12606.8 KFP18046.1 - 8.8e-25 85.4 1.2 1.5e-24 84.7 1.2 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 PHC2_SAM_assoc PF16616.5 KFP18046.1 - 0.12 13.2 4.8 5.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 ANAPC4_WD40 PF12894.7 KFP18047.1 - 8.7e-06 26.0 3.8 21 5.5 0.1 6.6 4 3 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 KFP18047.1 - 2.8e-05 24.4 0.0 0.00013 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFP18047.1 - 0.00016 21.6 0.2 0.00052 20.0 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KFP18047.1 - 0.00027 21.4 0.0 0.00074 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KFP18047.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFP18047.1 - 0.004 17.6 0.0 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PQQ_2 PF13360.6 KFP18047.1 - 0.05 13.2 0.0 1.5 8.4 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 KFP18047.1 - 0.1 13.5 1.1 19 6.3 0.2 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat Bromodomain PF00439.25 KFP18048.1 - 4.6e-44 148.4 3.0 2.8e-21 75.4 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFP18048.1 - 6.7e-30 103.1 0.2 1.8e-29 101.7 0.2 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YL1 PF05764.13 KFP18048.1 - 0.00043 20.5 21.0 0.00043 20.5 21.0 2.5 2 1 0 2 2 2 1 YL1 nuclear protein V_ATPase_I PF01496.19 KFP18048.1 - 1.2 7.0 6.8 2 6.2 6.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 KFP18048.1 - 3.4 7.8 14.4 0.65 10.1 7.5 2.4 2 1 0 2 2 2 0 DDHD domain Macoilin PF09726.9 KFP18048.1 - 3.6 6.0 19.0 5.9 5.3 19.0 1.3 1 0 0 1 1 1 0 Macoilin family AKAP95 PF04988.12 KFP18049.1 - 2.7e-20 73.2 2.0 2.9e-20 73.1 2.0 1.0 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFP18049.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KFP18049.1 - 0.021 14.0 0.2 0.021 14.0 0.2 1.0 1 0 0 1 1 1 0 Putative actin-like family zf-Di19 PF05605.12 KFP18049.1 - 0.021 15.1 0.2 0.024 14.9 0.2 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP18049.1 - 5.9 7.3 8.1 23 5.4 8.1 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP18051.1 - 5.7e-10 39.2 24.4 0.14 13.1 0.8 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP18051.1 - 0.00018 21.7 27.6 0.0023 18.3 0.4 5.8 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFP18051.1 - 0.0013 18.3 10.1 0.25 11.0 0.1 4.2 4 0 0 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFP18051.1 - 0.34 11.3 21.2 2.5 8.5 0.1 5.2 4 2 0 5 5 5 0 C2H2 type zinc-finger (2 copies) FeoC PF09012.10 KFP18051.1 - 0.37 10.9 1.6 1 9.5 1.6 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator zf-C2H2_jaz PF12171.8 KFP18051.1 - 0.89 9.9 12.0 0.66 10.3 2.4 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Mss51 PF13824.6 KFP18051.1 - 0.95 9.6 9.6 2.7 8.2 0.8 3.8 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 HNH_5 PF14279.6 KFP18051.1 - 1.1 9.2 5.9 4.1 7.3 3.0 2.8 2 1 0 2 2 2 0 HNH endonuclease zf-C2H2_7 PF15269.6 KFP18051.1 - 3.1 8.0 20.8 0.73 10.0 0.2 5.3 6 0 0 6 6 6 0 Zinc-finger Snf7 PF03357.21 KFP18052.1 - 2.9e-51 173.5 20.8 3.3e-51 173.3 20.8 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KFP18052.1 - 0.00075 19.9 1.5 0.00075 19.9 1.5 2.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KFP18052.1 - 0.026 14.8 0.7 0.026 14.8 0.7 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 KFP18052.1 - 0.033 14.1 21.4 0.52 10.3 0.7 3.5 2 1 1 3 3 3 0 Prefoldin subunit Alpha-E PF04168.12 KFP18052.1 - 0.08 12.7 1.6 0.11 12.3 0.8 1.5 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Hydantoinase_B PF02538.14 KFP18052.1 - 0.16 10.3 1.6 0.18 10.2 1.6 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase BCDHK_Adom3 PF10436.9 KFP18052.1 - 0.17 11.7 2.8 0.24 11.2 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Endotoxin_N PF03945.14 KFP18052.1 - 1.5 8.5 7.0 3.9 7.1 7.1 1.5 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain YlqD PF11068.8 KFP18052.1 - 1.8 8.9 18.1 7.6 6.9 5.0 2.1 1 1 1 2 2 2 0 YlqD protein GvpK PF05121.12 KFP18052.1 - 1.8 8.6 12.3 1.1 9.3 3.0 3.1 1 1 2 3 3 3 0 Gas vesicle protein K CorA PF01544.18 KFP18052.1 - 1.8 7.8 15.0 3.5 6.9 9.3 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Lyase_1 PF00206.20 KFP18053.1 - 4e-123 410.8 0.1 5.1e-123 410.4 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFP18053.1 - 7.9e-28 96.7 0.1 4e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus FAD_binding_2 PF00890.24 KFP18054.1 - 2.4e-126 422.2 2.4 3e-126 421.9 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFP18054.1 - 2.3e-38 131.1 0.0 3.5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KFP18054.1 - 8.8e-06 25.1 0.3 0.0022 17.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFP18054.1 - 1.5e-05 24.4 0.4 0.11 11.8 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KFP18054.1 - 0.00022 20.4 3.7 0.066 12.3 2.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFP18054.1 - 0.0041 16.4 0.1 0.0068 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFP18054.1 - 0.036 13.7 0.1 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFP18054.1 - 0.15 10.8 1.0 0.82 8.3 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFP18054.1 - 0.58 9.4 1.6 3.4 6.8 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MAGSP PF03082.14 KFP18055.1 - 0.14 11.8 1.9 0.22 11.1 1.9 1.3 1 0 0 1 1 1 0 Male accessory gland secretory protein PIN_3 PF13470.6 KFP18055.1 - 0.17 12.7 2.5 0.42 11.4 2.5 1.9 1 1 0 1 1 1 0 PIN domain Exonuc_VII_L PF02601.15 KFP18055.1 - 0.91 9.0 7.3 1.2 8.7 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SNF PF00209.18 KFP18056.1 - 2e-176 587.7 28.6 2.6e-176 587.4 28.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFP18057.1 - 6.9e-156 520.0 28.1 1.1e-155 519.4 28.1 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Telomerase_RBD PF12009.8 KFP18058.1 - 5.3e-41 139.9 5.5 1.5e-40 138.4 5.5 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KFP18058.1 - 2.1e-14 53.6 0.2 5e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TERT_thumb PF17984.1 KFP18058.1 - 0.0015 18.5 1.5 0.0049 16.8 1.5 1.8 1 0 0 1 1 1 1 Telomerase reverse transcriptase thumb DNA binding domain Lipoprotein_11 PF03260.13 KFP18058.1 - 0.0081 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lepidopteran low molecular weight (30 kD) lipoprotein WRKY PF03106.15 KFP18058.1 - 0.15 12.4 1.1 1.1 9.5 0.2 3.1 2 0 0 2 2 2 0 WRKY DNA -binding domain UBA2_C PF16195.5 KFP18058.1 - 1 10.1 2.8 2.3 9.0 2.8 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus CLPTM1 PF05602.12 KFP18059.1 - 7.8e-129 430.4 3.0 9.2e-129 430.2 3.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Acyltransferase PF01553.21 KFP18060.1 - 5.6e-17 61.6 0.0 9.8e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_8 PF13833.6 KFP18060.1 - 5.7e-12 45.3 5.1 1.5e-07 31.1 0.1 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP18060.1 - 7.8e-12 44.1 1.8 0.00044 20.0 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KFP18060.1 - 1.7e-09 36.5 3.7 0.00018 20.8 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFP18060.1 - 1.9e-08 34.7 3.4 7.4e-05 23.1 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP18060.1 - 0.00033 20.0 1.9 0.016 14.7 0.4 3.0 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 KFP18060.1 - 0.0046 16.9 0.2 0.55 10.2 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand PrgI PF12666.7 KFP18060.1 - 0.12 13.1 1.0 0.3 11.8 1.0 1.7 1 0 0 1 1 1 0 PrgI family protein zf-CHCC PF10276.9 KFP18063.1 - 2.2e-18 66.0 0.7 2.9e-18 65.6 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain Malic_M PF03949.15 KFP18064.1 - 2.7e-103 344.7 0.5 3.5e-103 344.4 0.5 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFP18064.1 - 8.6e-67 224.5 0.0 2.1e-66 223.2 0.0 1.7 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Cullin PF00888.22 KFP18065.1 - 7.8e-176 586.3 24.0 1e-175 585.9 24.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP18065.1 - 1.3e-26 92.4 4.7 1.3e-26 92.4 4.7 3.2 3 0 0 3 3 3 1 Cullin protein neddylation domain Rio2_N PF09202.11 KFP18065.1 - 0.0031 17.7 1.0 0.014 15.6 0.1 2.5 2 0 0 2 2 2 1 Rio2, N-terminal TFIIE_alpha PF02002.17 KFP18065.1 - 0.039 13.8 0.9 0.25 11.2 0.2 2.6 2 1 0 2 2 2 0 TFIIE alpha subunit DUF4423 PF14394.6 KFP18065.1 - 0.14 11.8 5.4 0.19 11.4 0.6 3.3 3 1 0 4 4 4 0 Domain of unknown function (DUF4423) OTCace PF00185.24 KFP18065.1 - 0.3 11.2 4.4 0.13 12.3 0.8 2.3 3 0 0 3 3 3 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MukF_M PF17192.4 KFP18065.1 - 0.53 10.0 6.3 6.5 6.5 0.1 3.5 2 1 1 3 3 3 0 MukF middle domain bZIP_1 PF00170.21 KFP18066.1 - 8.1e-21 73.9 11.6 1.4e-20 73.1 11.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFP18066.1 - 4e-19 67.8 1.7 1e-18 66.5 1.7 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFP18066.1 - 2e-07 31.0 11.0 3.4e-07 30.2 11.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP18066.1 - 0.0023 18.4 6.2 0.0043 17.5 6.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor MMgT PF10270.9 KFP18066.1 - 0.073 13.4 0.1 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Membrane magnesium transporter IMCp PF12314.8 KFP18066.1 - 0.23 11.8 0.2 0.23 11.8 0.2 1.9 2 0 0 2 2 2 0 Inner membrane complex protein Cadherin_tail PF15974.5 KFP18066.1 - 6.5 7.1 6.3 11 6.4 0.3 2.7 2 1 1 3 3 3 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Cyclin_N PF00134.23 KFP18068.1 - 1.3e-14 54.1 0.2 2.2e-14 53.3 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFP18068.1 - 3.8e-11 43.6 0.1 5.1e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin zf-C2H2 PF00096.26 KFP18074.1 - 9.3e-14 51.0 31.7 7.9e-05 22.9 8.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP18074.1 - 3.1e-10 40.0 13.7 1.8e-06 28.1 6.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP18074.1 - 1.8e-06 28.3 28.4 0.0091 16.8 7.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3850 PF12961.7 KFP18074.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) zf-C2H2_8 PF15909.5 KFP18074.1 - 0.92 9.8 11.0 0.37 11.1 6.7 2.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon DUF4692 PF15763.5 KFP18074.1 - 1.3 9.5 7.5 0.7 10.3 5.5 1.6 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FOXP-CC PF16159.5 KFP18074.1 - 1.7 9.3 9.3 1.3 9.7 0.8 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KFP18074.1 - 2.9 8.3 9.1 8.1 6.9 1.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PFK PF00365.20 KFP18080.1 - 1.4e-186 618.5 8.5 8.1e-107 356.8 1.8 3.1 2 1 0 2 2 2 2 Phosphofructokinase A_deamin PF02137.18 KFP18085.1 - 4.2e-109 365.0 0.0 6.4e-109 364.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFP18085.1 - 1.3e-24 86.7 0.1 4e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP18085.1 - 0.057 13.7 1.0 3.2 8.1 0.0 3.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 WD40 PF00400.32 KFP18086.1 - 5.9e-27 93.4 23.7 5.3e-07 30.2 0.4 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP18086.1 - 0.019 15.2 3.3 3.6 8.0 0.1 4.2 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1640 PF07798.11 KFP18086.1 - 0.073 13.1 2.7 0.12 12.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM76 PF16046.5 KFP18086.1 - 0.91 8.8 5.8 1.5 8.1 5.8 1.2 1 0 0 1 1 1 0 FAM76 protein NUDIX PF00293.28 KFP18087.1 - 1.6e-24 86.4 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain La PF05383.17 KFP18088.1 - 3.7e-14 52.5 0.2 7.9e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 La domain CxC2 PF18803.1 KFP18091.1 - 0.00018 21.6 0.5 0.00054 20.1 0.5 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Peptidase_M26_N PF05342.14 KFP18091.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region LRR_6 PF13516.6 KFP18091.1 - 0.051 13.6 8.2 2.1 8.6 0.1 5.0 7 0 0 7 7 7 0 Leucine Rich repeat ANF_receptor PF01094.28 KFP18092.1 - 5.3e-38 131.0 0.0 6e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region TrkA_N PF02254.18 KFP18092.1 - 0.18 12.1 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Glyco_trans_4_4 PF13579.6 KFP18092.1 - 4.8 7.6 10.6 0.59 10.6 2.9 2.3 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain C2 PF00168.30 KFP18093.1 - 6.6e-53 177.3 0.1 9.3e-26 90.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFP18093.1 - 0.0017 18.3 0.1 1.7 8.6 0.0 3.1 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KFP18093.1 - 0.029 13.9 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain OLF PF02191.16 KFP18094.1 - 1.2e-77 260.9 0.0 1.6e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain DUF1088 PF06469.11 KFP18094.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Plectin PF00681.20 KFP18095.1 - 4.6e-258 832.9 5.5 7e-21 73.8 0.0 23.4 19 5 7 26 26 26 20 Plectin repeat HTH_10 PF04967.12 KFP18095.1 - 5.4e-07 29.3 0.2 3 7.7 0.0 5.9 6 0 0 6 6 6 3 HTH DNA binding domain Toprim_Crpt PF13342.6 KFP18095.1 - 0.015 15.3 0.2 8.6 6.4 0.0 3.6 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase DUF1974 PF09317.11 KFP18095.1 - 0.017 14.7 7.6 6.4 6.3 0.0 6.2 6 1 0 7 7 7 0 Domain of unknown function (DUF1974) NUDIX PF00293.28 KFP18097.1 - 6.3e-10 39.2 0.6 1.2e-09 38.3 0.6 1.5 1 1 0 1 1 1 1 NUDIX domain adh_short PF00106.25 KFP18098.1 - 1.3e-48 165.0 0.5 1.5e-48 164.8 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP18098.1 - 2e-32 112.7 0.4 2.3e-32 112.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP18098.1 - 2.1e-10 40.8 0.5 2.9e-10 40.3 0.5 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KFP18098.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Kelch_1 PF01344.25 KFP18099.1 - 1.7e-74 245.2 16.8 1.1e-15 56.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP18099.1 - 2e-42 142.2 5.0 2.4e-08 34.0 0.0 6.4 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFP18099.1 - 1.2e-28 97.9 10.5 4.3e-05 23.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif BACK PF07707.15 KFP18099.1 - 1.4e-26 92.5 0.7 1.4e-26 92.5 0.7 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KFP18099.1 - 1.5e-26 92.1 9.5 9.9e-05 22.5 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP18099.1 - 1e-23 83.0 4.5 9.1e-05 22.4 0.0 6.3 4 2 2 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFP18099.1 - 8.3e-23 80.7 2.7 1.1e-22 80.4 1.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 KFP18099.1 - 2.4e-05 24.2 8.4 1.9 8.5 0.0 5.3 5 0 0 5 5 5 3 Kelch motif WD40 PF00400.32 KFP18100.1 - 2.2e-42 142.2 22.5 1.1e-05 26.0 0.2 10.8 10 1 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP18100.1 - 3.2e-21 75.4 0.3 8.7e-06 26.0 0.0 7.0 3 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP18100.1 - 8.8e-12 45.3 0.4 0.0095 15.8 0.0 5.1 2 1 2 5 5 5 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP18100.1 - 4.9e-05 22.5 4.0 0.033 13.1 0.0 4.9 3 2 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFP18100.1 - 0.00014 21.7 0.7 7.5 6.6 0.0 4.9 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KFP18100.1 - 0.0024 16.0 0.0 0.22 9.5 0.0 3.0 2 1 1 3 3 3 1 IKI3 family BBS2_Mid PF14783.6 KFP18100.1 - 0.004 17.2 0.0 0.11 12.5 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KFP18100.1 - 0.0052 16.7 0.4 0.024 14.5 0.1 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat Nbas_N PF15492.6 KFP18100.1 - 0.032 13.6 0.3 75 2.5 0.0 4.0 3 1 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PDZ PF00595.24 KFP18104.1 - 2.5e-61 204.0 10.0 3.5e-15 56.1 0.0 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 KFP18104.1 - 7.4e-49 163.4 13.1 3.1e-11 43.0 0.1 5.3 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 KFP18104.1 - 1.6e-25 89.2 0.1 4.1e-05 23.8 0.0 5.4 5 0 0 5 5 5 5 PDZ domain MAGI_u1 PF16663.5 KFP18104.1 - 3.4e-23 81.5 2.5 1.1e-22 79.8 2.5 2.0 1 0 0 1 1 1 1 Unstructured region on MAGI WW PF00397.26 KFP18104.1 - 3.5e-16 59.0 7.2 1.7e-09 37.6 0.3 3.2 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.21 KFP18104.1 - 1.5e-08 34.5 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KFP18104.1 - 7.6e-07 29.0 2.2 1.8 8.6 0.0 5.1 5 0 0 5 5 5 2 Tricorn protease PDZ domain MAGI_u5 PF16666.5 KFP18104.1 - 0.00071 19.7 2.9 0.00071 19.7 2.9 4.8 5 0 0 5 5 5 1 Unstructured region on MAGI PDZ_4 PF17816.1 KFP18104.1 - 0.021 15.2 0.0 36 4.8 0.0 3.8 3 0 0 3 3 3 0 PDZ domain DUF4462 PF14692.6 KFP18106.1 - 0.13 11.8 0.2 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) RVT_1 PF00078.27 KFP18109.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phtf-FEM1B_bdg PF12129.8 KFP18110.1 - 2.4e-63 212.6 0.2 2.4e-63 212.6 0.2 2.1 2 1 1 3 3 3 1 Male germ-cell putative homeodomain transcription factor Tmemb_185A PF10269.9 KFP18111.1 - 9.9e-14 51.6 3.0 1.3e-13 51.3 3.0 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF3522 PF12036.8 KFP18111.1 - 0.0089 16.3 4.7 0.012 15.9 3.5 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3522) CoA_binding_3 PF13727.6 KFP18111.1 - 4.7 7.2 12.3 0.24 11.4 6.0 1.8 1 1 0 2 2 2 0 CoA-binding domain Y_phosphatase PF00102.27 KFP18112.1 - 7.4e-82 274.4 0.2 1e-81 273.9 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP18112.1 - 4.8e-05 23.4 0.0 8.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFP18112.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain UBN_AB PF14075.6 KFP18112.1 - 0.019 14.7 0.4 0.044 13.5 0.4 1.6 1 0 0 1 1 1 0 Ubinuclein conserved middle domain ER-remodelling PF14755.6 KFP18112.1 - 0.19 12.1 5.5 0.46 10.8 4.1 2.4 2 0 0 2 2 2 0 Intracellular membrane remodeller GSAP-16 PF14959.6 KFP18114.1 - 5.3e-41 138.9 0.4 1.8e-40 137.2 0.1 2.2 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term Peptidase_S10 PF00450.22 KFP18115.1 - 4.7 6.5 28.7 0.28 10.5 5.1 3.4 2 1 0 3 3 3 0 Serine carboxypeptidase Fibrinogen_C PF00147.18 KFP18116.1 - 4.3e-89 298.1 10.0 5.8e-89 297.7 10.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FlaC_arch PF05377.11 KFP18116.1 - 0.004 17.5 4.3 0.0076 16.6 1.2 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) COLFI PF01410.18 KFP18116.1 - 0.0067 15.8 1.2 0.0096 15.2 0.1 1.8 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain BORCS6 PF10157.9 KFP18116.1 - 0.015 15.5 2.9 0.029 14.6 2.7 1.5 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Med9 PF07544.13 KFP18116.1 - 0.091 12.9 7.0 0.21 11.7 0.6 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MutS_II PF05188.17 KFP18116.1 - 0.099 12.9 1.7 0.16 12.3 0.3 2.0 2 1 1 3 3 2 0 MutS domain II Jnk-SapK_ap_N PF09744.9 KFP18116.1 - 0.1 12.8 8.4 0.18 12.1 8.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Prefoldin PF02996.17 KFP18116.1 - 0.16 11.9 8.4 0.88 9.5 1.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit Laminin_II PF06009.12 KFP18116.1 - 0.23 11.5 7.4 0.15 12.1 3.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 KFP18116.1 - 0.27 10.7 4.5 0.44 10.1 4.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFP18116.1 - 0.44 10.6 3.5 0.75 9.8 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.9 KFP18116.1 - 0.67 10.1 4.5 1.2 9.3 3.9 1.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Uds1 PF15456.6 KFP18116.1 - 1.1 9.5 5.9 2.4 8.3 5.9 1.5 1 0 0 1 1 1 0 Up-regulated During Septation LPP PF04728.13 KFP18116.1 - 1.2 9.6 6.8 6.1 7.3 0.6 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SOGA PF11365.8 KFP18116.1 - 1.8 9.8 6.3 8.7 7.5 6.3 2.1 1 1 0 1 1 1 0 Protein SOGA Csm1_N PF18504.1 KFP18116.1 - 1.8 9.0 9.7 1 9.7 1.3 2.8 3 0 0 3 3 2 0 Csm1 N-terminal domain CLZ PF16526.5 KFP18116.1 - 2 8.9 6.6 1.9 8.9 1.9 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KFP18116.1 - 2.7 8.5 5.4 8.3 7.0 1.8 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PRKG1_interact PF15898.5 KFP18116.1 - 2.9 8.8 10.0 14 6.7 9.8 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain EMP24_GP25L PF01105.24 KFP18116.1 - 3.1 7.7 5.7 5.4 6.9 3.8 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD YscO PF07321.12 KFP18116.1 - 3.8 7.5 8.7 2.8 7.9 2.7 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO XhlA PF10779.9 KFP18116.1 - 4.9 7.4 7.7 0.28 11.4 0.9 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 KFP18116.1 - 7.1 7.1 9.2 4.5 7.8 3.6 2.9 3 1 0 3 3 3 0 Snapin/Pallidin DUF4097 PF13349.6 KFP18117.1 - 1.3e-08 34.6 23.5 3.5e-05 23.3 23.0 2.9 1 1 0 1 1 1 1 Putative adhesin DUF2807 PF10988.8 KFP18117.1 - 0.016 15.0 1.0 0.016 15.0 1.0 2.8 2 1 1 3 3 3 0 Putative auto-transporter adhesin, head GIN domain LRR_6 PF13516.6 KFP18118.1 - 2.3e-24 83.3 24.3 0.06 13.4 0.1 14.0 15 0 0 15 15 15 6 Leucine Rich repeat LRR_4 PF12799.7 KFP18118.1 - 5.3e-15 55.3 18.9 0.0097 16.3 0.2 8.7 6 3 4 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP18118.1 - 1.2e-07 31.3 9.1 0.038 13.8 0.4 5.7 4 1 0 5 5 5 2 Leucine rich repeat F-box-like PF12937.7 KFP18118.1 - 5.4e-05 23.0 0.5 0.00012 21.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFP18118.1 - 0.00022 21.3 27.7 5.7 7.9 0.0 11.2 12 3 0 12 12 12 1 Leucine Rich Repeat F-box PF00646.33 KFP18118.1 - 0.0022 17.9 0.1 0.0077 16.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain SAM_Ste50p PF09235.10 KFP18118.1 - 0.088 13.1 12.0 31 4.9 0.3 6.2 6 1 1 7 7 7 0 Ste50p, sterile alpha motif LRR_8 PF13855.6 KFP18119.1 - 1e-28 98.8 20.9 2e-12 46.7 4.7 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP18119.1 - 3.7e-14 52.6 26.1 4.7e-06 26.8 4.4 4.8 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP18119.1 - 1.5e-13 50.8 0.9 1.6e-06 28.1 0.4 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP18119.1 - 2.9e-12 46.4 7.4 1.8e-05 24.4 0.2 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP18119.1 - 2e-05 24.5 16.3 1.2 9.9 1.5 7.1 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP18119.1 - 0.0019 18.1 16.2 6.3 7.1 1.0 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRRCT PF01463.24 KFP18119.1 - 0.021 15.4 0.0 2.8 8.7 0.0 3.0 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain Arm_2 PF04826.13 KFP18120.1 - 4.9e-70 235.9 6.6 5.4e-70 235.7 6.6 1.0 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 KFP18120.1 - 4.3e-06 26.6 1.5 0.12 12.4 0.1 3.5 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KFP18120.1 - 2e-05 24.7 1.0 0.00014 21.9 1.0 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP18120.1 - 2.2e-05 24.3 0.1 0.033 14.4 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KFP18120.1 - 0.00011 22.5 0.0 0.14 12.6 0.0 2.4 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 KFP18120.1 - 0.0015 19.0 0.1 3.1 8.4 0.0 2.8 3 0 0 3 3 3 2 HEAT-like repeat Cnd3 PF12719.7 KFP18120.1 - 0.0091 15.2 0.8 0.034 13.3 0.4 1.8 1 1 1 2 2 2 1 Nuclear condensing complex subunits, C-term domain UME PF08064.13 KFP18120.1 - 0.02 14.8 0.3 0.45 10.4 0.1 2.3 1 1 1 2 2 2 0 UME (NUC010) domain Atx10homo_assoc PF09759.9 KFP18120.1 - 0.023 14.7 1.2 0.28 11.2 1.2 2.4 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Lactamase_B_2 PF12706.7 KFP18121.1 - 1.8e-37 128.8 0.0 2.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFP18121.1 - 8e-13 48.6 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFP18121.1 - 0.014 15.4 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Peptidase_M16 PF00675.20 KFP18122.1 - 5e-54 182.3 0.1 7.8e-54 181.7 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP18122.1 - 2.2e-37 128.9 0.0 1.9e-36 125.8 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain RAC_head PF16717.5 KFP18123.1 - 6.8e-23 81.5 9.2 6.8e-23 81.5 9.2 4.5 5 2 0 5 5 5 1 Ribosome-associated complex head domain Myb_DNA-binding PF00249.31 KFP18123.1 - 2.3e-20 72.5 0.2 1.4e-11 44.4 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.31 KFP18123.1 - 2.2e-15 56.5 2.9 3.1e-15 56.0 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 KFP18123.1 - 3.3e-10 40.0 1.2 7e-06 26.2 0.1 3.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain GHBP PF12772.7 KFP18123.1 - 0.9 9.0 17.1 0.26 10.8 12.3 2.5 1 1 1 2 2 2 0 Growth hormone receptor binding AAA PF00004.29 KFP18125.1 - 1.2e-40 139.0 0.0 5e-40 137.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP18125.1 - 7.5e-09 35.3 0.1 1.7e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFP18125.1 - 4.8e-05 23.7 0.0 0.0054 17.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP18125.1 - 0.00035 20.6 0.1 0.0019 18.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP18125.1 - 0.0013 19.2 0.1 0.025 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFP18125.1 - 0.0018 18.4 0.0 0.0055 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFP18125.1 - 0.0037 16.5 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFP18125.1 - 0.0071 16.1 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP18125.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP18125.1 - 0.013 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP18125.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KFP18125.1 - 0.018 14.5 0.0 0.045 13.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KFP18125.1 - 0.058 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFP18125.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFP18125.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KFP18125.1 - 0.072 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KFP18125.1 - 0.074 12.8 0.3 0.76 9.5 0.0 2.5 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFP18125.1 - 0.089 13.2 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 KFP18125.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFP18125.1 - 0.14 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP18125.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sulfate_transp PF00916.20 KFP18126.1 - 6.4e-118 393.8 26.2 8.5e-118 393.4 26.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFP18126.1 - 4.8e-25 87.5 0.0 8.9e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain Ribosomal_S6 PF01250.17 KFP18126.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S6 BNR PF02012.20 KFP18127.1 - 6.8e-26 86.0 50.3 0.34 11.1 0.2 15.9 15 0 0 15 15 15 10 BNR/Asp-box repeat EGF_2 PF07974.13 KFP18127.1 - 1.2e-23 83.2 161.2 4.8e-05 23.6 11.6 9.6 9 1 0 9 9 9 8 EGF-like domain CHB_HEX_C PF03174.13 KFP18127.1 - 8.3e-09 35.3 4.2 59 3.8 0.0 12.0 14 0 0 14 14 14 0 Chitobiase/beta-hexosaminidase C-terminal domain EGF_Tenascin PF18720.1 KFP18127.1 - 7.6e-08 32.2 127.1 0.0039 17.2 11.4 9.1 8 0 0 8 8 8 7 Tenascin EGF domain Reeler PF02014.16 KFP18127.1 - 0.00085 20.1 0.1 0.0036 18.1 0.0 2.2 2 0 0 2 2 2 1 Reeler domain EB PF01683.18 KFP18127.1 - 0.00093 19.4 84.4 0.013 15.8 3.2 9.9 9 0 0 9 9 9 7 EB module hEGF PF12661.7 KFP18127.1 - 0.0036 17.9 9.3 0.0036 17.9 9.3 10.4 11 0 0 11 11 11 4 Human growth factor-like EGF OLF PF02191.16 KFP18127.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Olfactomedin-like domain Sortilin-Vps10 PF15902.5 KFP18127.1 - 0.41 9.4 9.3 52 2.4 0.0 7.6 12 0 0 12 12 12 0 Sortilin, neurotensin receptor 3, ORC5_C PF14630.6 KFP18129.1 - 7.9e-61 206.1 0.1 1.3e-60 205.3 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KFP18129.1 - 8.1e-16 58.9 0.1 1.3e-15 58.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP18129.1 - 8e-09 35.9 0.2 3.4e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain Kinesin PF00225.23 KFP18129.1 - 0.0045 16.0 0.8 0.0099 14.8 0.5 1.5 1 1 0 1 1 1 1 Kinesin motor domain ATPase_2 PF01637.18 KFP18129.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Microtub_bd PF16796.5 KFP18129.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding AAA_24 PF13479.6 KFP18129.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KFP18129.1 - 0.015 14.5 0.0 0.056 12.6 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.29 KFP18129.1 - 0.034 14.6 0.0 0.12 12.8 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFP18129.1 - 0.051 13.6 0.4 0.81 9.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFP18129.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KFP18129.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PHD PF00628.29 KFP18133.1 - 1.3e-08 34.6 12.1 3.5e-08 33.2 12.1 1.8 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KFP18133.1 - 3.7e-08 33.9 0.2 3.7e-08 33.9 0.2 3.7 3 1 0 3 3 3 1 SET domain PHD_2 PF13831.6 KFP18133.1 - 0.0057 16.2 8.5 0.013 15.0 8.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KFP18133.1 - 0.22 11.9 2.1 1.5 9.3 2.1 2.5 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Pkinase PF00069.25 KFP18134.1 - 5.8e-35 120.9 6.2 4.8e-22 78.6 0.2 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18134.1 - 1.3e-12 47.6 0.1 5.9e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP18134.1 - 0.0069 15.2 0.2 0.0069 15.2 0.2 2.1 1 1 0 2 2 2 1 Fungal protein kinase Peptidase_A17 PF05380.13 KFP18135.1 - 0.21 11.6 1.3 2.5 8.1 0.1 2.1 1 1 1 2 2 2 0 Pao retrotransposon peptidase TruD PF01142.18 KFP18138.1 - 9.6e-71 238.8 0.0 3.6e-65 220.4 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) RINT1_TIP1 PF04437.13 KFP18139.1 - 4.6e-134 448.0 14.1 4.6e-134 448.0 14.1 2.0 2 1 1 3 3 3 1 RINT-1 / TIP-1 family EF-hand_6 PF13405.6 KFP18140.1 - 0.043 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Rapsyn_N PF10579.9 KFP18140.1 - 0.052 13.6 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region SCA7 PF08313.12 KFP18141.1 - 2e-26 91.7 5.0 3.3e-26 91.0 3.2 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain OrsD PF12013.8 KFP18141.1 - 0.043 14.3 0.6 0.2 12.1 0.6 2.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Cadherin PF00028.17 KFP18143.1 - 1.1e-55 186.0 2.3 9.3e-17 61.3 0.1 6.3 6 0 0 6 6 6 6 Cadherin domain Cadherin_3 PF16184.5 KFP18143.1 - 1.3e-11 44.4 0.0 0.053 13.5 0.0 4.7 4 0 0 4 4 4 3 Cadherin-like Cadherin_2 PF08266.12 KFP18143.1 - 2e-07 30.7 0.0 1.7e-05 24.5 0.0 3.7 4 1 0 4 4 4 1 Cadherin-like Big_9 PF17963.1 KFP18143.1 - 0.052 14.3 9.9 13 6.6 0.0 5.7 6 0 0 6 6 6 0 Bacterial Ig domain Big_1 PF02369.16 KFP18143.1 - 0.83 9.7 5.9 2.8 8.0 0.1 3.8 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) MARVEL PF01284.23 KFP18144.1 - 1.2e-33 116.1 13.8 1.7e-33 115.7 13.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain SieB PF14163.6 KFP18144.1 - 0.19 11.2 1.3 0.28 10.7 0.5 1.6 1 1 0 1 1 1 0 Super-infection exclusion protein B Rab5-bind PF09311.11 KFP18145.1 - 0.00023 20.7 16.1 0.00023 20.7 16.1 2.2 1 1 0 2 2 2 1 Rabaptin-like protein Spc7 PF08317.11 KFP18145.1 - 0.0068 15.3 42.2 0.024 13.5 16.5 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFP18145.1 - 0.011 15.7 25.1 0.011 15.7 25.1 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.11 KFP18145.1 - 0.021 15.4 8.2 0.021 15.4 8.2 2.8 2 2 1 3 3 3 0 Syntaxin 6, N-terminal ATG16 PF08614.11 KFP18145.1 - 0.023 15.0 36.5 0.025 14.8 22.9 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF5113 PF17140.4 KFP18145.1 - 0.53 10.1 8.1 0.037 13.8 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5113) GAS PF13851.6 KFP18145.1 - 0.64 9.3 45.9 0.19 11.1 19.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.9 KFP18145.1 - 0.85 9.9 29.5 2 8.7 15.4 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein TPR_MLP1_2 PF07926.12 KFP18145.1 - 1.1 9.3 42.0 0.89 9.6 20.2 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KFP18145.1 - 1.6 9.0 30.8 0.36 11.1 10.3 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) DUF745 PF05335.13 KFP18145.1 - 2.1 8.0 21.7 1.3 8.7 7.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KFP18145.1 - 5.8 7.0 26.0 1.4 9.0 4.5 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KFP18145.1 - 9.3 5.5 32.2 1 8.6 11.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Lipase PF00151.19 KFP18146.1 - 9.8e-61 205.9 0.0 1.1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFP18146.1 - 0.0036 18.0 1.5 0.0064 17.1 1.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP18146.1 - 0.0061 15.9 0.0 0.0065 15.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase PF00151.19 KFP18147.1 - 1.1e-73 248.5 0.1 1.4e-73 248.2 0.1 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 KFP18147.1 - 9.9e-06 26.3 0.0 1.1e-05 26.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KFP18147.1 - 0.018 14.6 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KFP18147.1 - 0.027 13.7 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KFP18147.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KFP18147.1 - 0.087 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Lipase PF00151.19 KFP18148.1 - 8.9e-71 238.9 0.1 1.2e-70 238.5 0.1 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFP18148.1 - 9.8e-09 35.8 0.2 1.5e-08 35.2 0.2 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain TraI_2_C PF07515.11 KFP18148.1 - 0.15 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term HSP70 PF00012.20 KFP18149.1 - 2.1e-06 26.2 0.0 0.04 12.1 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein GA-like PF17573.2 KFP18149.1 - 0.058 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 GA-like domain FGGY_C PF02782.16 KFP18149.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Enolase_C PF00113.22 KFP18150.1 - 5.4e-25 88.2 0.0 7.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFP18150.1 - 3.6e-16 59.5 1.5 1.9e-10 41.0 0.1 2.3 2 0 0 2 2 2 2 Enolase, N-terminal domain DUF4462 PF14692.6 KFP18152.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Homeodomain PF00046.29 KFP18153.1 - 8.6e-09 35.1 1.3 1.1e-08 34.7 1.3 1.2 1 0 0 1 1 1 1 Homeodomain Ion_trans_2 PF07885.16 KFP18154.1 - 2e-29 101.4 22.2 3.2e-18 65.5 4.0 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KFP18154.1 - 0.00021 20.6 14.5 0.018 14.3 3.5 2.4 2 1 0 2 2 2 2 Ion transport protein MFS_1 PF07690.16 KFP18155.1 - 4.3e-45 154.2 36.0 3.8e-38 131.3 25.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP18155.1 - 2.2e-10 40.0 25.2 5.1e-09 35.5 2.4 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter LacY_symp PF01306.19 KFP18155.1 - 0.0076 15.1 16.8 0.01 14.6 7.1 2.9 2 1 0 2 2 2 2 LacY proton/sugar symporter S_4TM PF18159.1 KFP18155.1 - 0.12 11.6 0.2 0.3 10.4 0.2 1.6 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain CPP1-like PF11833.8 KFP18155.1 - 1 9.0 3.5 2.6 7.7 2.9 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PDZ_6 PF17820.1 KFP18156.1 - 2.3e-11 43.4 0.1 4.3e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.22 KFP18156.1 - 2e-08 34.0 13.5 4e-08 33.0 13.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ_2 PF13180.6 KFP18156.1 - 3.2e-08 33.8 0.1 7.2e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP18156.1 - 2.5e-07 30.9 0.1 6.5e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFP18156.1 - 0.0036 17.6 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain MMM1 PF10296.9 KFP18156.1 - 0.041 12.9 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Homeodomain PF00046.29 KFP18157.1 - 9.5e-12 44.6 0.1 1.8e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain C2 PF00168.30 KFP18159.1 - 4.3e-19 68.7 1.4 1.6e-18 66.9 0.0 2.5 3 0 0 3 3 3 1 C2 domain RBD-FIP PF09457.10 KFP18159.1 - 1.7e-16 59.8 3.0 3.7e-16 58.8 3.0 1.6 1 0 0 1 1 1 1 FIP domain DUF4462 PF14692.6 KFP18161.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP18162.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Cullin PF00888.22 KFP18163.1 - 6.9e-14 51.4 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Herpes_pp85 PF04637.12 KFP18163.1 - 0.0044 15.5 0.0 0.0066 14.9 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DNA_repr_REX1B PF14966.6 KFP18163.1 - 0.024 15.3 0.1 0.052 14.2 0.1 1.6 1 0 0 1 1 1 0 DNA repair REX1-B DUF4853 PF16145.5 KFP18163.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) PCI PF01399.27 KFP18164.1 - 9.7e-20 71.0 0.1 9.7e-20 71.0 0.1 4.3 5 0 0 5 5 5 1 PCI domain Avl9 PF09794.9 KFP18165.1 - 2.8e-11 42.7 0.1 6.1e-07 28.5 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KFP18165.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 KFP18165.1 - 2e-08 34.2 0.1 5.8e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Toxin-deaminase PF14424.6 KFP18165.1 - 0.0024 18.0 0.1 0.0045 17.1 0.1 1.4 1 0 0 1 1 1 1 The BURPS668_1122 family of deaminases DUF4373 PF14297.6 KFP18165.1 - 0.088 13.6 0.1 0.49 11.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4373) Mtc PF03820.17 KFP18166.1 - 1.3e-55 188.7 0.0 1.4e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF3574 PF12098.8 KFP18166.1 - 0.077 12.8 0.1 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) AhpC-TSA PF00578.21 KFP18167.1 - 2.7e-36 124.2 0.0 3.8e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFP18167.1 - 1.1e-15 57.6 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFP18167.1 - 3.4e-14 52.4 0.1 5.4e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KFP18167.1 - 0.018 15.0 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC Endothelin PF00322.17 KFP18167.1 - 0.11 12.1 0.3 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Endothelin family Pkinase PF00069.25 KFP18169.1 - 6.8e-66 222.3 0.0 9.6e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18169.1 - 6.9e-34 117.3 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP18169.1 - 4.5e-23 81.7 0.0 1.4e-22 80.2 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFP18169.1 - 4.3e-05 23.0 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP18169.1 - 0.0011 17.9 0.0 0.0033 16.2 0.0 1.6 1 1 0 2 2 2 1 Fungal protein kinase Arteri_nucleo PF01481.16 KFP18169.1 - 0.24 11.7 1.7 6.1 7.2 0.0 3.1 3 1 0 3 3 3 0 Arterivirus nucleocapsid protein RGS PF00615.19 KFP18171.1 - 6.3e-33 113.5 5.2 6.3e-33 113.5 5.2 1.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 KFP18171.1 - 8e-05 22.4 0.1 0.00014 21.7 0.1 1.4 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain RRM_1 PF00076.22 KFP18172.1 - 1e-60 201.4 0.0 1.3e-21 76.2 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP18172.1 - 2.9e-09 36.6 0.0 5.4e-05 23.0 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFP18172.1 - 1.8e-08 34.4 0.2 0.27 11.4 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP18172.1 - 9.2e-05 22.4 0.3 0.16 12.0 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.12 KFP18172.1 - 0.001 18.9 0.0 0.41 10.4 0.0 2.6 3 0 0 3 3 3 2 Calcipressin Nup35_RRM PF05172.13 KFP18172.1 - 0.001 19.0 0.2 0.37 10.8 0.2 3.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP18172.1 - 0.011 15.8 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif Cas_Cas2CT1978 PF09707.10 KFP18172.1 - 0.12 12.4 0.0 12 6.0 0.0 2.9 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) DbpA PF03880.15 KFP18172.1 - 0.16 12.0 0.0 4.1 7.5 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Syja_N PF02383.18 KFP18173.1 - 4.2e-98 328.6 0.6 8e-98 327.7 0.6 1.5 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KFP18173.1 - 2.7e-23 81.8 0.0 1.4e-22 79.6 0.0 2.2 2 0 0 2 2 2 1 Inositol phosphatase HSM3_C PF18794.1 KFP18173.1 - 0.028 14.0 0.4 1.1 8.8 0.2 2.7 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, C terminal domain MCM_bind PF09739.9 KFP18174.1 - 8.7e-234 777.3 0.0 9.8e-234 777.1 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor DDHD PF02862.17 KFP18175.1 - 2.1e-52 178.5 0.1 1.6e-51 175.6 0.0 2.3 2 0 0 2 2 2 1 DDHD domain SAM_1 PF00536.30 KFP18175.1 - 2.5e-13 50.2 0.0 5.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.20 KFP18175.1 - 3.5e-10 40.3 3.7 0.00011 22.7 0.4 2.7 1 1 1 2 2 2 2 WWE domain SAM_2 PF07647.17 KFP18175.1 - 9e-05 22.5 0.0 0.00037 20.5 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KFP18175.1 - 0.03 14.4 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 IGR protein motif Sec8_exocyst PF04048.14 KFP18175.1 - 0.086 12.7 1.0 0.22 11.4 1.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PAP2 PF01569.21 KFP18176.1 - 1.7e-28 99.1 0.9 1.7e-28 99.1 0.9 1.5 2 0 0 2 2 2 1 PAP2 superfamily Bax1-I PF01027.20 KFP18176.1 - 0.071 12.9 0.8 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PAP2_3 PF14378.6 KFP18176.1 - 0.91 9.2 6.4 33 4.1 6.4 2.6 1 1 0 1 1 1 0 PAP2 superfamily Sec1 PF00995.23 KFP18180.1 - 3.6e-105 353.4 0.3 4.3e-105 353.1 0.3 1.1 1 0 0 1 1 1 1 Sec1 family AftA_C PF12249.8 KFP18180.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal PH PF00169.29 KFP18181.1 - 7.2e-13 49.0 0.8 1.8e-12 47.7 0.8 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFP18181.1 - 0.00078 19.8 0.6 0.013 15.9 0.6 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP18181.1 - 0.019 15.4 0.8 0.019 15.4 0.8 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DTW PF03942.15 KFP18181.1 - 0.14 11.8 4.2 0.1 12.3 1.2 2.1 1 1 0 2 2 2 0 DTW domain DUF3055 PF11256.8 KFP18181.1 - 0.26 11.6 2.4 1.5 9.1 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3055) Aph-1 PF06105.12 KFP18182.1 - 5.2e-76 255.1 9.3 5.8e-76 254.9 9.3 1.0 1 0 0 1 1 1 1 Aph-1 protein OST3_OST6 PF04756.13 KFP18182.1 - 5.8 6.2 11.9 0.026 13.9 1.6 2.2 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family CARMIL_C PF16000.5 KFP18183.1 - 4.7e-104 348.3 10.2 4.7e-104 348.3 10.2 3.1 2 1 0 2 2 2 1 CARMIL C-terminus Carm_PH PF17888.1 KFP18183.1 - 1e-22 80.3 0.0 2.5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 KFP18183.1 - 4.9e-10 38.6 27.8 0.0022 17.9 0.1 8.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 KFP18183.1 - 0.0053 17.2 27.3 2.5 8.6 1.0 6.5 3 2 4 8 8 8 5 Leucine Rich repeats (2 copies) Muted PF14942.6 KFP18183.1 - 0.035 14.4 4.3 3.1 8.1 0.7 3.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein IL34 PF15036.6 KFP18183.1 - 0.045 13.8 0.2 0.13 12.3 0.2 1.8 1 0 0 1 1 1 0 Interleukin 34 Ribosomal_L34 PF00468.17 KFP18183.1 - 0.21 11.6 0.5 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L34 LRR_1 PF00560.33 KFP18183.1 - 1.1 10.1 17.3 82 4.4 0.3 7.8 8 0 0 8 8 8 0 Leucine Rich Repeat PL48 PF15903.5 KFP18185.1 - 5.4e-175 581.4 0.3 8.7e-175 580.7 0.3 1.3 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 HEAT_2 PF13646.6 KFP18185.1 - 2.7e-05 24.4 2.5 0.00017 21.9 0.2 2.7 1 1 1 2 2 2 1 HEAT repeats Arm PF00514.23 KFP18185.1 - 0.014 15.4 4.7 1.8 8.7 0.1 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SHE3 PF17078.5 KFP18185.1 - 0.064 13.0 4.1 0.25 11.0 4.1 2.1 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 HR1 PF02185.16 KFP18185.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.8 3 0 0 3 3 3 0 Hr1 repeat Geminin PF07412.12 KFP18186.1 - 8.2e-80 267.2 12.2 9.1e-80 267.1 12.2 1.0 1 0 0 1 1 1 1 Geminin UPF0242 PF06785.11 KFP18186.1 - 0.0061 16.7 9.6 0.0099 16.0 9.4 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 KFP18186.1 - 0.01 15.9 1.9 0.01 15.9 1.9 2.0 2 0 0 2 2 2 1 Laminin Domain II FapA PF03961.13 KFP18186.1 - 0.012 14.3 2.3 0.014 14.1 2.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KFP18186.1 - 0.032 14.0 1.3 0.032 14.0 1.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Phage_GPO PF05929.11 KFP18186.1 - 0.035 13.7 2.6 0.048 13.3 2.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Csm1_N PF18504.1 KFP18186.1 - 0.051 13.9 9.0 0.056 13.8 3.9 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Val_tRNA-synt_C PF10458.9 KFP18186.1 - 0.17 12.2 12.1 0.3 11.4 1.0 2.8 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm CRA PF06589.11 KFP18186.1 - 0.3 11.2 4.8 0.52 10.4 4.8 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Fzo_mitofusin PF04799.13 KFP18186.1 - 0.36 10.4 3.6 0.76 9.3 3.6 1.6 1 1 0 1 1 1 0 fzo-like conserved region DUF5094 PF17015.5 KFP18186.1 - 0.53 10.4 8.1 1.4 9.0 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) DUF641 PF04859.12 KFP18186.1 - 0.87 9.9 9.2 0.42 10.9 3.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CCDC-167 PF15188.6 KFP18186.1 - 1.9 8.9 10.4 6.4 7.2 10.4 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF5101 PF17031.5 KFP18186.1 - 7.8 6.7 12.5 0.13 12.4 2.7 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5101) DUF4566 PF15130.6 KFP18187.1 - 1.9e-138 459.2 2.5 2.1e-138 459.1 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) 4HBT PF03061.22 KFP18188.1 - 9.5e-15 54.7 0.2 1.7e-14 54.0 0.1 1.4 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFP18188.1 - 3.8e-05 24.1 0.1 4.7e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 KFP18188.1 - 0.005 17.0 0.2 0.029 14.5 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4442) Exo_endo_phos PF03372.23 KFP18189.1 - 7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DOMON PF03351.17 KFP18189.1 - 0.094 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 DOMON domain 7tm_1 PF00001.21 KFP18191.1 - 7.5e-55 186.1 16.7 9.8e-55 185.7 16.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP18191.1 - 3.3e-07 29.9 2.3 3.3e-07 29.9 2.3 2.2 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KFP18191.1 - 6.4e-06 25.7 14.2 6.4e-06 25.7 14.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srd PF10317.9 KFP18191.1 - 0.0028 16.9 21.0 0.12 11.6 21.0 2.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd DUF3382 PF11862.8 KFP18191.1 - 5 7.5 7.9 1.2 9.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Myelin_MBP PF01669.17 KFP18192.1 - 1.6e-61 207.4 7.2 2.6e-61 206.7 7.2 1.3 1 0 0 1 1 1 1 Myelin basic protein zf-C2H2 PF00096.26 KFP18193.1 - 4.2e-27 93.1 88.1 0.00026 21.2 7.8 10.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18193.1 - 2.3e-20 71.5 83.3 0.0048 17.6 0.7 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP18193.1 - 7.6e-09 35.6 2.2 7.6e-09 35.6 2.2 12.8 14 1 0 14 14 13 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP18193.1 - 4.4e-07 29.5 50.8 2.6e-06 27.1 2.0 8.2 8 0 0 8 8 7 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KFP18193.1 - 2.6e-06 27.6 31.3 0.6 10.4 0.3 6.1 4 2 0 4 4 4 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFP18193.1 - 0.026 14.9 49.0 0.044 14.1 0.4 7.7 5 2 3 8 8 8 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KFP18193.1 - 0.058 13.0 0.3 0.058 13.0 0.3 6.3 6 2 1 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KFP18193.1 - 0.2 12.1 0.0 0.2 12.1 0.0 8.0 6 2 1 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger ARS2 PF04959.13 KFP18193.1 - 0.98 9.8 7.9 2.3 8.5 0.4 3.1 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_3rep PF18868.1 KFP18193.1 - 1.8 9.2 25.1 0.046 14.4 3.1 6.6 6 2 2 8 8 8 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 KFP18193.1 - 2.9 7.9 40.0 0.14 12.1 2.0 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KFP18193.1 - 6.9 7.0 23.8 2.3 8.6 0.0 5.7 5 1 1 6 6 6 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFP18197.1 - 1.4e-12 47.8 20.2 0.0053 17.1 1.0 5.4 4 2 1 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFP18197.1 - 1.3e-10 41.2 28.9 0.038 14.5 1.3 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18197.1 - 1.1e-09 38.3 23.7 0.069 14.0 2.8 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP18197.1 - 4.7e-05 23.3 21.8 0.024 14.6 2.4 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HE PF16278.5 KFP18197.1 - 0.00036 20.9 11.9 2.4 8.7 0.0 5.9 5 0 0 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KFP18197.1 - 0.0032 17.8 9.3 0.023 15.1 1.9 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF760 PF05542.11 KFP18197.1 - 0.028 14.8 0.3 0.47 10.8 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF760) Lar_restr_allev PF14354.6 KFP18197.1 - 0.037 14.4 1.4 16 5.9 0.0 4.5 6 0 0 6 6 6 0 Restriction alleviation protein Lar zf-C2H2_jaz PF12171.8 KFP18197.1 - 0.043 14.1 0.8 0.043 14.1 0.8 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KFP18197.1 - 0.059 13.5 11.1 6.4 7.0 0.1 5.4 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFP18197.1 - 0.071 13.0 1.8 0.075 13.0 0.2 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KFP18197.1 - 0.4 10.6 2.1 4.1 7.4 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 KFP18197.1 - 1.1 9.1 15.8 0.13 12.0 2.4 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KFP18197.1 - 3.7 7.5 8.6 4.5 7.2 0.2 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF678 PF05077.12 KFP18197.1 - 4.1 7.6 9.8 34 4.7 0.0 5.1 5 1 0 5 5 5 0 Protein of unknown function (DUF678) ADH_zinc_N PF00107.26 KFP18198.1 - 1.9e-26 92.6 0.0 3.8e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP18198.1 - 2.5e-14 54.5 0.0 3.8e-13 50.6 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP18198.1 - 1.1e-07 31.7 0.6 0.00042 20.2 0.0 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DUF3318 PF11780.8 KFP18198.1 - 0.28 11.1 0.4 1.8 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) zf-H2C2_2 PF13465.6 KFP18200.1 - 1.1e-33 114.2 48.6 2e-07 31.1 0.9 7.1 7 0 0 7 7 7 6 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP18200.1 - 6.2e-12 45.0 45.7 1.4e-06 28.0 2.3 7.1 7 0 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP18200.1 - 8.1e-12 44.9 53.9 0.0004 20.7 4.1 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18200.1 - 3.1e-06 27.5 49.7 0.0037 18.0 3.6 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger DUF3268 PF11672.8 KFP18200.1 - 0.88 9.9 6.4 9.4 6.6 2.0 2.6 2 0 0 2 2 2 0 zinc-finger-containing domain zf-Di19 PF05605.12 KFP18200.1 - 3 8.2 27.5 2.7 8.4 4.6 4.6 1 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KFP18200.1 - 3.6 7.3 18.7 2.3 7.9 1.3 4.7 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain VPDSG-CTERM PF18205.1 KFP18200.1 - 6.9 6.6 4.7 3.5 7.5 0.9 2.3 2 0 0 2 2 2 0 VPDSG-CTERM motif Actin_micro PF17003.5 KFP18200.1 - 8.2 5.5 14.0 1.1e+02 1.8 5.4 4.1 1 1 1 2 2 2 0 Putative actin-like family zf-H2C2_2 PF13465.6 KFP18201.1 - 8.2e-07 29.2 8.3 3.4e-05 24.1 1.1 14.8 17 0 0 17 17 17 8 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP18201.1 - 1.2e-05 24.9 4.1 1.2e-05 24.9 4.1 12.7 13 0 0 13 13 13 7 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFP18201.1 - 9e-05 23.0 128.1 0.25 12.3 1.2 18.0 18 0 0 18 18 18 7 C2H2-type zinc finger zf-met PF12874.7 KFP18201.1 - 0.0051 17.1 2.4 0.0051 17.1 2.4 9.0 10 0 0 10 10 10 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFP18201.1 - 0.011 16.1 0.6 0.011 16.1 0.6 14.0 6 5 8 15 15 15 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KFP18201.1 - 0.012 16.0 6.0 0.021 15.3 1.6 17.9 19 0 0 19 19 19 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 KFP18201.1 - 0.23 11.4 0.0 0.23 11.4 0.0 4.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Peptidase_M20 PF01546.28 KFP18202.1 - 2.3e-38 132.0 0.0 3.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFP18202.1 - 7.5e-12 45.1 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFP18202.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFP18203.1 - 2.4e-36 125.4 0.0 3.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFP18203.1 - 8e-16 57.9 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFP18203.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 PIP49_C PF12260.8 KFP18204.1 - 6.3e-59 198.8 1.8 7.1e-59 198.6 0.8 1.6 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFP18204.1 - 4.3e-11 42.9 0.7 7.1e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 DUF4708 PF15813.5 KFP18205.1 - 1.3e-28 99.9 0.2 1.5e-28 99.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) PET10 PF17316.2 KFP18205.1 - 0.13 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Petite colonies protein 10 Cyt-b5 PF00173.28 KFP18206.1 - 4.8e-08 33.0 0.0 6.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TIM21 PF08294.11 KFP18209.1 - 3.3e-49 166.5 0.2 3.7e-49 166.3 0.2 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KFP18209.1 - 2.1e-07 30.7 0.0 6.5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.7 KFP18210.1 - 6.5e-10 38.7 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP18210.1 - 6e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFP18210.1 - 0.067 13.1 0.1 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 F-box CUB PF00431.20 KFP18213.1 - 6.1e-40 136.0 0.5 1.7e-26 92.7 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.18 KFP18213.1 - 1.4e-07 31.6 2.4 1.4e-07 31.6 2.4 2.7 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A C1q PF00386.21 KFP18214.1 - 9.8e-23 80.7 0.2 1.1e-22 80.6 0.2 1.0 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFP18214.1 - 0.028 14.3 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 BclA C-terminal domain RVT_1 PF00078.27 KFP18219.1 - 0.044 13.3 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RTTN_N PF14726.6 KFP18220.1 - 2.6e-30 105.1 9.4 1.3e-29 102.8 0.0 5.5 5 1 0 5 5 5 1 Rotatin, an armadillo repeat protein, centriole functioning V-set PF07686.17 KFP18222.1 - 3.9e-18 65.6 0.2 8.8e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP18222.1 - 2.2e-11 44.2 0.2 7.9e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP18222.1 - 6.3e-09 35.9 0.2 0.0015 18.6 0.0 3.3 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP18222.1 - 1.3e-05 25.1 0.2 0.0014 18.6 0.1 2.5 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18222.1 - 0.0017 18.6 0.7 3 8.3 0.1 3.7 1 1 1 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFP18222.1 - 0.036 13.6 0.1 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain IRS PF02174.17 KFP18223.1 - 3.5e-30 103.8 0.0 6e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.29 KFP18223.1 - 0.0015 19.0 0.6 0.0029 18.1 0.6 1.5 1 0 0 1 1 1 1 PH domain CREPT PF16566.5 KFP18223.1 - 0.056 13.6 0.4 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2200 PF09966.9 KFP18225.1 - 0.028 14.5 2.2 0.04 14.1 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) COG2 PF06148.11 KFP18225.1 - 1.8 8.7 7.7 0.37 10.9 1.2 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HALZ PF02183.18 KFP18225.1 - 3.9 7.8 9.5 2.6 8.4 2.0 3.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper PRKG1_interact PF15898.5 KFP18225.1 - 7.9 7.5 23.1 3.7 8.5 6.4 3.9 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Thioredoxin_6 PF13848.6 KFP18226.1 - 2.2e-28 99.5 0.2 1.4e-25 90.3 0.6 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFP18226.1 - 3.4e-25 88.0 0.0 3.4e-24 84.8 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP18226.1 - 8e-05 23.1 0.2 0.00074 19.9 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFP18226.1 - 0.005 17.1 0.2 2.6 8.4 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KFP18226.1 - 0.081 13.1 0.2 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like FAM176 PF14851.6 KFP18226.1 - 0.087 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Transglut_C PF00927.22 KFP18227.1 - 4.3e-31 107.2 0.0 3.7e-18 65.6 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 KFP18227.1 - 8.5e-12 45.5 0.1 1.7e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily RVT_1 PF00078.27 KFP18228.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cid2 PF09774.9 KFP18229.1 - 4.1e-16 59.8 5.7 1.3e-14 54.9 5.7 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 FOXP-CC PF16159.5 KFP18229.1 - 2.2 9.0 7.0 23 5.7 0.4 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Sulfotransfer_1 PF00685.27 KFP18231.1 - 6.1e-11 42.3 0.0 1.6e-09 37.6 0.0 3.5 1 1 0 1 1 1 1 Sulfotransferase domain DUF4962 PF16332.5 KFP18231.1 - 2.1e-05 23.2 4.0 2.1e-05 23.2 4.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) Sulfotransfer_3 PF13469.6 KFP18231.1 - 2.7e-05 24.7 0.0 0.0027 18.1 0.0 3.3 2 1 0 2 2 2 1 Sulfotransferase family DUF4078 PF13300.6 KFP18231.1 - 0.13 12.6 3.2 0.29 11.5 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) KN_motif PF12075.8 KFP18234.1 - 6.5e-20 70.6 0.4 1.6e-19 69.4 0.4 1.7 1 0 0 1 1 1 1 KN motif Ank_2 PF12796.7 KFP18236.1 - 3.7e-34 117.2 11.6 1.3e-17 64.1 0.5 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP18236.1 - 1.7e-27 94.6 6.9 4.4e-07 30.1 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP18236.1 - 8.7e-27 92.8 10.6 6.7e-12 45.4 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18236.1 - 6.7e-25 84.4 3.7 4.3e-07 29.7 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KFP18236.1 - 1.4e-24 86.1 3.0 7.5e-12 45.5 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF1694 PF07997.11 KFP18236.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) KxDL PF10241.9 KFP18236.1 - 0.079 13.3 0.9 12 6.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Tmemb_cc2 PF10267.9 KFP18236.1 - 0.22 10.7 5.1 0.07 12.3 1.6 1.7 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Dmrt1 PF12374.8 KFP18237.1 - 1.3e-29 102.5 4.6 1.3e-29 102.5 4.6 2.5 3 1 0 3 3 3 1 Double-sex mab3 related transcription factor 1 DMA PF03474.14 KFP18238.1 - 2.3e-16 59.1 0.1 3.7e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 DMRTA motif DUF4490 PF14892.6 KFP18239.1 - 0.018 15.1 0.3 0.044 13.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) SNF2_N PF00176.23 KFP18240.1 - 1.3e-72 244.5 2.0 1.3e-72 244.5 2.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KFP18240.1 - 2.8e-21 75.4 0.1 3.2e-20 72.0 0.1 2.6 2 0 0 2 2 2 1 Bromodomain HSA PF07529.13 KFP18240.1 - 3.7e-21 75.2 16.2 3.7e-21 75.2 16.2 4.7 4 0 0 4 4 4 1 HSA Helicase_C PF00271.31 KFP18240.1 - 1.7e-20 73.4 0.5 4.7e-19 68.8 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 KFP18240.1 - 7.5e-19 68.1 7.9 7.5e-19 68.1 7.9 6.1 6 3 0 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex BRK PF07533.16 KFP18240.1 - 8.3e-18 63.7 0.1 1.7e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 BRK domain QLQ PF08880.11 KFP18240.1 - 1.5e-14 53.4 4.3 3.2e-14 52.4 4.3 1.6 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KFP18240.1 - 1.2e-08 35.2 0.0 1.2e-08 35.2 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFP18240.1 - 0.00022 21.0 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NAD_binding_5 PF07994.12 KFP18240.1 - 1.6 8.1 4.4 3.4 6.9 4.4 1.5 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Ldl_recept_a PF00057.18 KFP18241.1 - 2.6e-101 331.5 149.3 1e-14 54.4 13.4 8.6 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFP18241.1 - 6.2e-44 148.2 14.2 8.1e-11 42.2 0.0 6.5 5 1 1 6 6 6 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP18241.1 - 3.7e-20 71.9 30.5 3.6e-10 39.9 5.2 6.3 5 1 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP18241.1 - 6e-07 29.6 5.2 6e-07 29.6 5.2 11.0 6 3 1 7 7 7 2 Calcium-binding EGF domain SGL PF08450.12 KFP18241.1 - 1.8e-06 27.7 0.3 0.035 13.7 0.1 3.3 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 KFP18241.1 - 4.5e-05 23.3 26.7 0.038 13.9 0.9 6.5 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 KFP18241.1 - 0.00052 20.3 19.3 0.0033 17.7 4.6 9.5 8 1 1 9 9 9 3 EGF-like domain Arylesterase PF01731.20 KFP18241.1 - 0.065 13.4 0.0 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Arylesterase CPL PF08144.11 KFP18242.1 - 4.9e-47 159.9 0.0 4.9e-47 159.9 0.0 3.8 4 1 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 KFP18242.1 - 0.0028 17.3 0.7 10 6.0 0.1 4.4 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat Arm-DNA-bind_2 PF12167.8 KFP18242.1 - 0.037 13.9 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain PsbI PF02532.14 KFP18243.1 - 1.1 9.3 5.8 0.19 11.7 1.3 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) CARM1 PF11531.8 KFP18244.1 - 4.7e-24 84.7 1.4 8.8e-24 83.9 1.4 1.5 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal PrmA PF06325.13 KFP18244.1 - 9.1e-10 38.4 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFP18244.1 - 2.2e-09 37.9 0.0 6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFP18244.1 - 1.4e-07 30.8 0.0 2.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 KFP18244.1 - 1.5e-07 32.0 0.0 5.1e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP18244.1 - 7.4e-07 28.9 0.0 5.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KFP18244.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP18244.1 - 2.3e-05 24.3 0.0 0.00037 20.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFP18244.1 - 2.5e-05 24.2 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KFP18244.1 - 6.6e-05 22.8 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 KFP18244.1 - 0.00017 21.0 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 KFP18244.1 - 0.00044 19.9 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PRMT5_C PF17286.2 KFP18244.1 - 0.0027 17.6 0.1 0.0048 16.8 0.1 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 KFP18244.1 - 0.0059 17.3 0.0 0.018 15.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.14 KFP18244.1 - 0.0096 15.4 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KFP18244.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KFP18244.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G IL1_propep PF02394.16 KFP18244.1 - 0.14 13.0 0.3 1.9 9.4 0.4 2.2 2 0 0 2 2 2 0 Interleukin-1 propeptide Methyltransf_24 PF13578.6 KFP18244.1 - 0.16 13.0 0.0 0.39 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RFX1_trans_act PF04589.13 KFP18245.1 - 1.2e-35 123.1 18.7 1.2e-35 123.1 18.7 2.3 2 0 0 2 2 2 1 RFX1 transcription activation region RFX_DNA_binding PF02257.15 KFP18245.1 - 1.1e-33 115.7 0.1 3.6e-33 114.0 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain HisKA PF00512.25 KFP18245.1 - 0.018 15.1 0.2 0.047 13.7 0.2 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Pox_D5 PF03288.16 KFP18245.1 - 0.062 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like Metallophos PF00149.28 KFP18246.1 - 5.1e-26 92.5 0.1 9.4e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 KFP18246.1 - 1.5e-18 66.9 7.7 1.8e-11 44.3 3.3 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP18246.1 - 4.2e-18 63.5 2.1 5.3e-06 25.6 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP18246.1 - 2.7e-15 54.9 2.5 0.0015 18.3 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP18246.1 - 1e-12 47.7 2.3 1.5e-05 24.8 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair PPP5 PF08321.12 KFP18246.1 - 8.6e-11 42.0 1.1 1.3e-09 38.2 0.0 3.0 3 0 0 3 3 3 1 PPP5 TPR repeat region EF-hand_5 PF13202.6 KFP18246.1 - 5e-10 38.4 4.7 0.00042 19.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KFP18246.1 - 0.0013 18.7 4.4 0.16 11.9 0.7 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP18246.1 - 0.069 13.5 0.0 26 5.3 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Nup54 PF13874.6 KFP18247.1 - 5.5e-46 156.2 2.4 5.5e-46 156.2 2.4 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 KFP18247.1 - 3.1e-18 65.4 7.9 3.1e-18 65.4 7.9 2.8 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain XhlA PF10779.9 KFP18247.1 - 0.079 13.2 1.2 0.26 11.5 1.2 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Regulator_TrmB PF11495.8 KFP18247.1 - 0.1 11.7 0.9 18 4.4 0.0 2.9 2 1 0 3 3 3 0 Archaeal transcriptional regulator TrmB KRTAP PF11759.8 KFP18247.1 - 0.23 12.0 13.8 0.55 10.8 13.8 1.7 1 0 0 1 1 1 0 Keratin-associated matrix Keratin_2_head PF16208.5 KFP18247.1 - 2.2 8.4 21.0 4.1 7.5 21.0 1.5 1 0 0 1 1 1 0 Keratin type II head TBCC_N PF16752.5 KFP18247.1 - 6.3 7.3 10.9 1.4 9.4 3.8 3.2 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain CD36 PF01130.21 KFP18248.1 - 1.7e-148 495.0 0.7 2.1e-148 494.8 0.7 1.0 1 0 0 1 1 1 1 CD36 family DUF2975 PF11188.8 KFP18248.1 - 1 9.2 5.9 0.73 9.7 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Gal-bind_lectin PF00337.22 KFP18249.1 - 2.2e-25 88.7 0.0 2.6e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin tRNA_anti-codon PF01336.25 KFP18249.1 - 0.026 14.5 0.2 7.5 6.6 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Ank_5 PF13857.6 KFP18250.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP18250.1 - 0.11 13.1 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Septin PF00735.18 KFP18251.1 - 7.7e-99 330.5 1.3 7.7e-99 330.5 1.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFP18251.1 - 5.9e-07 29.6 0.0 5.9e-07 29.6 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF3080 PF11279.8 KFP18251.1 - 9e-05 21.8 6.6 0.00014 21.2 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) Roc PF08477.13 KFP18251.1 - 0.0004 20.6 0.0 0.0015 18.8 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP18251.1 - 0.00048 20.6 0.1 0.0016 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP18251.1 - 0.00049 20.4 0.3 0.0017 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 KFP18251.1 - 0.002 17.7 0.0 0.0062 16.1 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_23 PF13476.6 KFP18251.1 - 0.0089 16.6 21.5 0.23 11.9 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFP18251.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KFP18251.1 - 0.026 14.1 9.0 0.97 8.9 0.1 3.6 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFP18251.1 - 0.03 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Fzo_mitofusin PF04799.13 KFP18251.1 - 0.072 12.6 8.1 0.21 11.1 8.1 1.8 1 0 0 1 1 1 0 fzo-like conserved region RsgA_GTPase PF03193.16 KFP18251.1 - 0.075 12.9 6.7 0.2 11.6 0.0 3.1 3 1 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 KFP18251.1 - 0.097 12.7 9.9 1.4 8.9 0.1 3.2 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 KFP18251.1 - 0.26 11.8 0.1 0.26 11.8 0.1 2.6 2 2 0 2 2 1 0 ABC transporter DUF87 PF01935.17 KFP18251.1 - 0.28 11.2 7.5 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Atg14 PF10186.9 KFP18251.1 - 0.3 10.1 15.0 0.43 9.6 13.5 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cyclin_N PF00134.23 KFP18252.1 - 7.4e-24 83.9 0.7 5.4e-23 81.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP18252.1 - 0.00049 20.2 4.0 0.0011 19.0 2.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain IL8 PF00048.20 KFP18254.1 - 7.8e-16 58.0 0.9 8.5e-16 57.9 0.9 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Exo_endo_phos PF03372.23 KFP18255.1 - 1.5e-21 77.0 0.0 1.2e-20 74.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KFP18255.1 - 3.3e-12 46.0 12.7 2.5e-11 43.1 10.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP18255.1 - 2.7e-09 37.1 18.6 1e-07 32.1 3.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP18255.1 - 0.014 14.9 0.9 0.029 13.9 0.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KFP18255.1 - 0.038 14.1 11.2 3.9 7.8 2.7 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KFP18255.1 - 0.099 13.3 18.5 8.1 7.4 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat Cadherin_3 PF16184.5 KFP18256.1 - 1.3e-223 727.1 31.5 3e-29 101.3 1.3 13.7 13 2 0 13 13 13 12 Cadherin-like Calx-beta PF03160.14 KFP18256.1 - 1.3e-77 256.3 6.4 7.6e-17 61.3 0.0 5.9 5 0 0 5 5 5 5 Calx-beta domain VWC PF00093.18 KFP18256.1 - 2.9e-34 117.2 136.2 8.1e-10 38.9 19.8 18.0 11 4 6 17 17 17 6 von Willebrand factor type C domain Big_9 PF17963.1 KFP18256.1 - 4.3e-16 59.4 46.1 2.3e-06 28.2 2.6 12.8 13 0 0 13 13 13 4 Bacterial Ig domain Cadherin_4 PF17803.1 KFP18256.1 - 8.6e-15 55.1 25.9 0.0046 17.5 0.2 10.1 11 0 0 11 11 11 3 Bacterial cadherin-like domain VSP PF03302.13 KFP18256.1 - 7.2e-07 28.4 28.2 1.1e-05 24.5 3.0 12.8 1 1 9 11 11 11 8 Giardia variant-specific surface protein GF_recep_IV PF14843.6 KFP18256.1 - 1e-05 25.3 71.0 1.8e-05 24.6 36.1 11.8 2 1 10 12 12 12 7 Growth factor receptor domain IV Furin-like_2 PF15913.5 KFP18256.1 - 0.0014 18.8 45.4 0.0022 18.1 15.3 13.6 2 1 15 17 17 17 8 Furin-like repeat, cysteine-rich DUF5026 PF16429.5 KFP18256.1 - 0.12 12.4 0.0 0.71 10.0 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Mob_synth_C PF06463.13 KFP18257.1 - 1.7e-42 144.4 0.0 2.5e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFP18257.1 - 4.5e-32 111.7 0.1 6.6e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFP18257.1 - 5.2e-10 39.7 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KFP18257.1 - 8.6e-06 25.9 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lipoprotein_9 PF03180.14 KFP18257.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 NLPA lipoprotein MoaC PF01967.21 KFP18258.1 - 1.8e-28 99.3 0.0 2.5e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 MoaC family Kinesin PF00225.23 KFP18261.1 - 5.8e-97 324.6 0.5 5.8e-97 324.6 0.5 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP18261.1 - 1.1e-26 93.5 1.3 7.1e-26 90.9 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding HEPN_Swt1 PF18731.1 KFP18261.1 - 0.013 15.8 0.6 0.05 14.0 0.0 2.3 2 0 0 2 2 2 0 Swt1-like HEPN PRKG1_interact PF15898.5 KFP18261.1 - 7.4 7.5 24.8 0.57 11.1 5.4 3.8 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Ion_trans_2 PF07885.16 KFP18262.1 - 7.1e-23 80.4 8.9 2e-13 50.1 3.2 2.3 2 0 0 2 2 2 2 Ion channel CCDC85 PF10226.9 KFP18263.1 - 7.4e-64 215.0 5.3 7.4e-64 215.0 5.3 2.5 3 0 0 3 3 3 1 CCDC85 family bZIP_1 PF00170.21 KFP18263.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.2 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 KFP18263.1 - 0.61 10.4 10.4 2.5 8.5 0.1 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KFP18263.1 - 1.2 9.0 5.9 3 7.8 1.4 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Pkinase PF00069.25 KFP18266.1 - 2.9e-16 59.6 0.2 1.5e-13 50.8 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18266.1 - 4e-10 39.4 0.1 2.4e-09 36.9 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP18266.1 - 0.0013 17.6 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase WD-3 PF09765.9 KFP18267.1 - 1.2e-109 366.2 0.0 1.3e-109 366.0 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 KFP18267.1 - 1.2e-30 105.4 4.4 2.2e-30 104.7 4.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFP18267.1 - 5.4e-06 26.6 4.7 1.2e-05 25.5 4.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 KFP18267.1 - 0.056 13.7 0.1 0.091 13.0 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 KFP18267.1 - 0.098 13.0 5.4 0.3 11.4 5.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP18267.1 - 0.13 12.3 3.5 0.49 10.5 3.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KFP18267.1 - 0.17 12.0 1.9 0.32 11.1 1.9 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C2H2 PF00096.26 KFP18271.1 - 7.5e-27 92.3 55.3 5.2e-06 26.6 2.8 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18271.1 - 1.2e-15 56.9 51.8 0.0017 19.0 1.3 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP18271.1 - 3.5e-15 55.6 55.3 2.9e-07 30.6 1.3 9.0 9 0 0 9 9 8 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP18271.1 - 5e-05 23.0 35.9 9.1e-05 22.1 3.9 4.8 5 0 0 5 5 4 2 C2H2-type zinc-finger domain DUF3268 PF11672.8 KFP18271.1 - 0.00043 20.6 15.5 0.0089 16.3 1.3 2.7 2 1 0 2 2 2 2 zinc-finger-containing domain BSP_II PF05432.11 KFP18271.1 - 0.012 15.3 11.3 0.02 14.6 11.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.8 KFP18271.1 - 0.031 14.5 6.7 0.062 13.6 6.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GAGA PF09237.11 KFP18271.1 - 0.068 13.0 6.9 2.6 7.9 0.3 2.9 2 1 0 2 2 2 0 GAGA factor Astro_capsid_p PF12226.8 KFP18271.1 - 0.15 11.2 5.2 0.24 10.5 5.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HTH_18 PF12833.7 KFP18271.1 - 0.42 10.9 1.3 3.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Ribosomal_60s PF00428.19 KFP18271.1 - 0.53 10.9 10.9 1.1 9.9 10.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Actin_micro PF17003.5 KFP18271.1 - 1.5 7.9 11.0 5.1 6.2 0.2 3.7 3 1 0 3 3 3 0 Putative actin-like family NOA36 PF06524.12 KFP18271.1 - 2.9 7.2 25.4 0.016 14.5 8.5 3.1 3 0 0 3 3 3 0 NOA36 protein FAM176 PF14851.6 KFP18271.1 - 3.1 7.5 6.7 7.2 6.3 6.7 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KFP18271.1 - 4 5.4 15.1 5.4 5.0 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFP18271.1 - 4.3 5.5 5.9 6 5.0 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2256 PF10013.9 KFP18271.1 - 5.5 7.2 14.3 14 5.9 0.4 4.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) CENP-B_dimeris PF09026.10 KFP18271.1 - 6.2 7.3 13.6 14 6.2 13.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 KFP18271.1 - 6.6 6.2 16.1 0.68 9.5 9.8 2.1 2 0 0 2 2 2 0 PPP4R2 PAP_central PF04928.17 KFP18272.1 - 3.2e-115 383.3 0.0 4.5e-115 382.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFP18272.1 - 9.9e-26 90.4 1.7 4.4e-19 68.8 0.1 2.4 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFP18272.1 - 1.9e-12 47.3 0.1 5.5e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 KFP18272.1 - 0.0057 16.9 0.1 0.015 15.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4269) Nrap_D2 PF17403.2 KFP18272.1 - 0.0077 16.0 0.1 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain RHD_DNA_bind PF00554.22 KFP18273.1 - 3.2e-75 251.7 0.0 5.3e-75 251.0 0.0 1.4 1 0 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KFP18273.1 - 2.4e-37 127.1 0.0 4e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Rel homology dimerisation domain TPD PF14811.6 KFP18274.1 - 0.021 14.7 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif TFIID_20kDa PF03847.13 KFP18274.1 - 0.8 10.3 2.9 63 4.2 0.0 3.5 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A DUF3342 PF11822.8 KFP18275.1 - 2e-36 124.1 1.5 3.9e-36 123.1 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CHORD PF04968.12 KFP18275.1 - 0.023 15.4 4.3 0.03 15.1 1.3 2.8 2 1 0 2 2 2 0 CHORD PAN_3 PF08277.12 KFP18275.1 - 0.073 12.9 0.7 0.19 11.6 0.7 1.6 1 0 0 1 1 1 0 PAN-like domain Cadherin PF00028.17 KFP18276.1 - 9.6e-27 93.3 0.6 2.4e-17 63.2 0.0 2.4 2 1 0 2 2 2 2 Cadherin domain RET_CLD1 PF17756.1 KFP18276.1 - 0.077 13.3 0.0 11 6.4 0.0 2.2 2 0 0 2 2 2 0 RET Cadherin like domain 1 Cadherin PF00028.17 KFP18278.1 - 5.9e-08 33.1 0.1 1.5e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 Cadherin domain Orf78 PF06024.12 KFP18278.1 - 0.059 13.7 0.7 0.059 13.7 0.7 1.7 2 0 0 2 2 2 0 Orf78 (ac78) COX6C PF02937.15 KFP18278.1 - 0.077 13.1 0.3 0.21 11.8 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF3377 PF11857.8 KFP18278.1 - 0.09 12.7 2.6 0.39 10.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 KFP18278.1 - 0.12 12.5 0.1 0.43 10.7 0.1 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RBFA PF02033.18 KFP18278.1 - 0.45 11.0 3.5 0.42 11.1 0.3 2.3 2 1 1 3 3 3 0 Ribosome-binding factor A Aha1_N PF09229.11 KFP18279.1 - 9.2e-37 126.3 1.6 1.7e-36 125.4 1.3 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFP18279.1 - 4.5e-18 65.7 0.2 1.4e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein UPF0564 PF10595.9 KFP18281.1 - 6.5e-60 203.1 44.5 6.5e-60 203.1 44.5 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 HXXSHH PF07586.11 KFP18281.1 - 0.019 14.6 0.4 0.039 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF4090 PF13319.6 KFP18281.1 - 0.05 13.8 0.2 0.16 12.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) Cpn60_TCP1 PF00118.24 KFP18282.1 - 5e-157 523.4 15.8 5.6e-157 523.3 15.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 KFP18282.1 - 0.062 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X LRR_8 PF13855.6 KFP18283.1 - 6.9e-28 96.2 31.8 2.7e-11 43.1 2.2 5.1 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KFP18283.1 - 7.7e-17 61.1 23.2 4.1e-06 27.0 0.8 6.1 2 2 6 8 8 8 5 Leucine Rich repeats (2 copies) fn3 PF00041.21 KFP18283.1 - 2.3e-11 43.9 0.1 6.1e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRR_9 PF14580.6 KFP18283.1 - 0.0056 16.2 0.4 0.53 9.8 0.2 2.5 2 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KFP18283.1 - 0.067 13.8 27.4 4.7 8.1 0.1 8.6 7 2 1 8 8 8 0 Leucine Rich Repeat FERM_M PF00373.18 KFP18284.1 - 1.4e-42 144.8 0.0 3.5e-42 143.5 0.0 1.7 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 KFP18284.1 - 3.6e-34 116.8 6.1 1e-33 115.3 6.1 1.8 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 KFP18284.1 - 1.4e-10 41.6 0.0 5.2e-09 36.6 0.0 2.9 3 0 0 3 3 3 1 PH domain FERM_N PF09379.10 KFP18284.1 - 0.022 14.7 0.0 0.084 12.8 0.0 2.1 1 1 0 1 1 1 0 FERM N-terminal domain PH_8 PF15409.6 KFP18284.1 - 0.042 14.1 0.1 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Rad10 PF03834.14 KFP18284.1 - 0.1 12.6 2.8 8 6.5 0.1 3.0 3 0 0 3 3 3 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) TGFb_propeptide PF00688.18 KFP18286.1 - 1.2e-36 126.7 0.4 2e-36 126.0 0.4 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP18286.1 - 1e-34 119.6 0.6 1.9e-34 118.7 0.6 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain FMN_dh PF01070.18 KFP18287.1 - 7.8e-132 439.5 0.7 9.3e-132 439.3 0.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFP18287.1 - 7.6e-07 28.4 1.9 3.8e-06 26.1 0.9 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFP18287.1 - 6.3e-05 22.3 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KFP18287.1 - 7.8e-05 22.1 0.6 0.21 10.9 0.1 2.7 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFP18287.1 - 0.00035 20.1 0.7 0.0059 16.1 0.1 2.7 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 KFP18287.1 - 0.0026 16.9 0.1 2.1 7.4 0.0 2.4 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NMO PF03060.15 KFP18287.1 - 0.0037 16.7 1.9 0.012 15.1 2.0 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.21 KFP18287.1 - 0.0092 15.2 0.2 0.03 13.5 0.0 1.9 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 KFP18287.1 - 0.012 14.9 0.6 0.078 12.3 0.0 2.4 3 0 0 3 3 3 0 Thiamine monophosphate synthase MFS_MOT1 PF16983.5 KFP18287.1 - 0.021 15.2 0.3 0.039 14.4 0.3 1.4 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily G3P_antiterm PF04309.12 KFP18287.1 - 0.027 13.9 0.1 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator CdhD PF03599.16 KFP18287.1 - 0.052 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Thioredoxin PF00085.20 KFP18288.1 - 1e-13 51.1 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KFP18288.1 - 0.076 13.1 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Ras PF00071.22 KFP18291.1 - 7.8e-56 188.1 0.3 9.3e-56 187.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP18291.1 - 1.7e-19 70.2 0.0 3.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP18291.1 - 2e-10 40.4 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP18291.1 - 7.1e-09 35.8 0.1 5.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP18291.1 - 6.9e-05 22.5 0.2 0.0002 20.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP18291.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KFP18291.1 - 0.01 15.2 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 KFP18291.1 - 0.012 15.2 0.2 0.055 13.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain ThiF PF00899.21 KFP18291.1 - 0.11 11.8 2.0 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 ThiF family MeaB PF03308.16 KFP18291.1 - 0.15 11.0 0.4 2 7.3 0.3 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Yae1_N PF09811.9 KFP18292.1 - 1.7e-13 50.0 2.0 2.5e-13 49.5 2.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2385 PF09539.10 KFP18292.1 - 0.022 15.3 0.1 0.13 12.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) Pou PF00157.17 KFP18293.1 - 6.3e-24 83.7 2.6 3.3e-14 52.6 0.1 3.0 3 0 0 3 3 3 2 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KFP18293.1 - 1.1e-17 63.7 0.9 1.1e-17 63.7 0.9 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP18293.1 - 0.0065 16.4 0.2 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain HOCHOB PF17943.1 KFP18293.1 - 0.0073 17.0 0.1 0.016 15.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox-cysteine loop-homeobox FtsX_ECD PF18075.1 KFP18293.1 - 0.025 15.2 0.0 0.025 15.2 0.0 3.0 3 0 0 3 3 3 0 FtsX extracellular domain CLN3 PF02487.17 KFP18293.1 - 0.28 10.2 4.2 0.58 9.2 4.2 1.5 1 0 0 1 1 1 0 CLN3 protein Macoilin PF09726.9 KFP18293.1 - 0.7 8.4 15.3 0.09 11.3 7.0 2.2 2 0 0 2 2 2 0 Macoilin family V_ATPase_I PF01496.19 KFP18293.1 - 2.5 5.9 6.2 4.4 5.1 6.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 KFP18293.1 - 6.2 6.9 11.6 13 5.8 11.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Gti1_Pac2 PF09729.9 KFP18293.1 - 9.4 6.3 9.5 7.5 6.6 6.3 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Clathrin PF00637.20 KFP18294.1 - 5.2e-23 81.5 1.0 5.2e-23 81.5 1.0 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KFP18294.1 - 0.00041 20.8 0.2 0.0012 19.3 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 ANAPC4_WD40 PF12894.7 KFP18294.1 - 0.0014 18.9 0.2 0.31 11.4 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 KFP18294.1 - 0.022 15.1 1.9 0.022 15.1 1.9 2.4 2 0 0 2 2 2 0 Ring finger domain Vps39_1 PF10366.9 KFP18294.1 - 0.024 14.9 3.8 0.42 10.9 0.1 3.4 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 KFP18294.1 - 0.03 14.3 1.7 0.11 12.5 1.7 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KFP18294.1 - 0.079 12.7 4.5 0.23 11.3 4.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KFP18294.1 - 0.1 12.9 2.3 0.17 12.2 1.2 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 KFP18294.1 - 0.2 11.7 2.0 0.6 10.2 2.0 1.8 1 0 0 1 1 1 0 Zinc-finger TPR_7 PF13176.6 KFP18294.1 - 0.34 11.0 1.4 15 5.9 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP18294.1 - 0.93 9.8 3.0 6.1 7.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KFP18294.1 - 3.1 7.9 5.2 19 5.4 5.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger RD3 PF14473.6 KFP18296.1 - 2.9e-49 166.3 3.5 4.2e-49 165.8 3.5 1.2 1 0 0 1 1 1 1 RD3 protein Peptidase_S28 PF05577.12 KFP18296.1 - 0.029 13.2 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 zf-TRAF PF02176.18 KFP18297.1 - 2.4e-23 82.6 24.5 3.4e-15 56.5 6.1 4.1 3 1 1 4 4 3 2 TRAF-type zinc finger zf-ACC PF17848.1 KFP18297.1 - 4.8e-06 26.5 1.9 0.0004 20.4 0.2 3.3 2 0 0 2 2 2 1 Acetyl-coA carboxylase zinc finger domain zf-C3HC4_2 PF13923.6 KFP18297.1 - 6.6e-06 25.9 6.7 6.6e-06 25.9 6.7 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP18297.1 - 2.4e-05 24.1 5.5 2.4e-05 24.1 5.5 4.3 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KFP18297.1 - 4.7e-05 23.8 8.1 4.7e-05 23.8 8.1 3.4 2 1 1 3 3 2 1 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KFP18297.1 - 0.0003 20.9 5.1 0.0003 20.9 5.1 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFP18297.1 - 0.00076 19.5 4.9 0.00076 19.5 4.9 3.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP18297.1 - 0.0064 16.4 6.1 0.0064 16.4 6.1 4.4 3 1 2 5 5 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP18297.1 - 0.0075 16.6 5.6 0.0075 16.6 5.6 3.8 3 1 1 4 4 2 1 Ring finger domain DUF4941 PF16299.5 KFP18297.1 - 0.011 15.1 1.1 0.018 14.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) zf-RING_6 PF14835.6 KFP18297.1 - 0.014 15.3 1.3 0.014 15.3 1.3 3.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF484 PF04340.12 KFP18297.1 - 0.042 13.5 3.8 0.11 12.1 3.0 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF484 DUF4279 PF14106.6 KFP18297.1 - 2.4 8.4 6.3 2.5 8.4 0.7 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4279) Methyltransf_31 PF13847.6 KFP18297.1 - 5.9 6.7 8.1 1.8 8.3 1.6 2.4 1 1 0 2 2 2 0 Methyltransferase domain Tropomyosin_1 PF12718.7 KFP18297.1 - 6 7.0 13.8 12 6.1 13.8 1.5 1 0 0 1 1 1 0 Tropomyosin like Exonuc_VII_L PF02601.15 KFP18297.1 - 8.4 5.9 8.5 14 5.1 8.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Myb_DNA-binding PF00249.31 KFP18298.1 - 4.6e-19 68.3 0.0 1.5e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP18298.1 - 1.6e-08 34.3 3.6 0.00073 19.4 0.1 3.2 2 1 1 3 3 3 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KFP18298.1 - 3.9e-06 27.0 3.0 0.0018 18.5 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.24 KFP18298.1 - 2.7e-05 24.8 0.2 0.00014 22.5 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain Ion_trans PF00520.31 KFP18299.1 - 1.5e-35 122.6 10.7 2e-35 122.2 10.7 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KFP18299.1 - 5.2e-18 65.2 0.1 1.4e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 KFP18299.1 - 1.5e-14 53.8 0.0 3.6e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP18299.1 - 6.9e-12 45.2 3.5 6.9e-12 45.2 3.5 2.0 2 0 0 2 2 2 1 Ion channel PAS PF00989.25 KFP18299.1 - 9.4e-07 28.8 0.1 4.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KFP18299.1 - 3.8e-05 23.9 0.0 8.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold Cupin_3 PF05899.12 KFP18299.1 - 0.021 14.5 0.1 0.072 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PAS_4 PF08448.10 KFP18299.1 - 0.026 14.8 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Cupin_2 PF07883.11 KFP18299.1 - 0.033 13.9 0.1 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 Cupin domain MBOAT PF03062.19 KFP18301.1 - 5.2e-43 147.7 21.8 7.1e-43 147.3 21.8 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SERTA PF06031.13 KFP18303.1 - 1.8e-15 56.3 0.1 3e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 SERTA motif DUF508 PF04370.12 KFP18303.1 - 0.085 12.6 6.6 0.17 11.6 6.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF508) DUF3446 PF11928.8 KFP18303.1 - 0.84 10.0 18.4 0.22 11.8 15.1 1.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Herpes_pp85 PF04637.12 KFP18303.1 - 1.5 7.2 9.6 2.1 6.6 9.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) UTP25 PF06862.12 KFP18305.1 - 2.1e-193 643.4 5.1 2.7e-193 643.1 5.1 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KFP18305.1 - 0.0059 16.4 0.0 0.34 10.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S10 PF00338.22 KFP18306.1 - 2.5e-26 91.8 0.3 3.4e-26 91.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-C2H2_6 PF13912.6 KFP18307.1 - 5.9e-14 51.7 6.7 6.1e-07 29.3 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFP18307.1 - 1e-07 32.2 6.5 0.017 15.9 0.2 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger ELM2 PF01448.24 KFP18307.1 - 1.1e-07 32.5 1.3 2.9e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain zf-C2H2 PF00096.26 KFP18307.1 - 1e-06 28.8 7.4 0.027 14.9 1.2 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type Myb_DNA-binding PF00249.31 KFP18307.1 - 1.8e-05 24.9 0.3 4e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.8 KFP18307.1 - 0.0032 17.7 2.2 1.3 9.4 0.7 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP18307.1 - 0.0053 17.1 3.2 0.098 13.1 0.1 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Myb_DNA-bind_7 PF15963.5 KFP18307.1 - 0.0085 16.0 0.2 0.0085 16.0 0.2 2.5 2 0 0 2 2 2 1 Myb DNA-binding like zf-C2H2_2 PF12756.7 KFP18307.1 - 0.058 13.7 0.0 0.058 13.7 0.0 3.8 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) ClpS PF02617.17 KFP18308.1 - 8e-23 80.0 0.3 2.1e-22 78.7 0.3 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 KFP18308.1 - 3.1e-21 75.3 7.8 3.1e-21 75.3 7.8 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Tetraspanin PF00335.20 KFP18309.1 - 1.6e-28 100.0 3.9 2.1e-28 99.6 3.9 1.1 1 0 0 1 1 1 1 Tetraspanin family MtrD PF04207.12 KFP18309.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D GLTSCR1 PF15249.6 KFP18312.1 - 1.2e-32 112.3 1.3 4.1e-32 110.6 1.3 2.0 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein PIP49_C PF12260.8 KFP18314.1 - 1.1e-11 44.7 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 COX7a PF02238.15 KFP18317.1 - 1.4e-09 38.2 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII MTA_R1 PF17226.2 KFP18318.1 - 6.5e-30 103.1 2.7 1.4e-29 102.0 2.2 1.9 2 0 0 2 2 2 1 MTA R1 domain BAH PF01426.18 KFP18318.1 - 1.7e-29 102.2 4.3 8.9e-20 70.8 0.2 2.6 2 1 1 3 3 3 2 BAH domain ELM2 PF01448.24 KFP18318.1 - 7.4e-17 61.8 0.2 7.4e-17 61.8 0.2 2.9 4 0 0 4 4 4 1 ELM2 domain GATA PF00320.27 KFP18318.1 - 1.2e-09 37.6 8.0 2.8e-09 36.4 8.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 KFP18318.1 - 4.7e-06 26.7 0.1 1.8e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP18318.1 - 0.0091 15.9 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 Myb DNA-binding like Herpes_US12 PF05363.12 KFP18318.1 - 0.029 15.1 0.2 0.11 13.2 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus US12 family 3-HAO PF06052.12 KFP18319.1 - 3.4e-72 241.0 0.3 2.4e-70 235.0 0.2 2.0 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KFP18319.1 - 2.2e-12 46.5 0.0 4.1e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFP18319.1 - 3.8e-05 23.3 0.0 0.0093 15.6 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFP18319.1 - 0.0013 18.6 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain DUF2428 PF10350.9 KFP18322.1 - 1.5e-104 349.1 1.4 4.1e-104 347.7 1.4 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) MyTH4 PF00784.17 KFP18323.1 - 1.3e-33 115.7 1.6 1.3e-33 115.7 1.6 2.5 3 0 0 3 3 3 1 MyTH4 domain PH PF00169.29 KFP18323.1 - 7.6e-28 97.1 0.7 8.7e-18 64.8 0.1 3.7 3 0 0 3 3 3 2 PH domain FERM_M PF00373.18 KFP18323.1 - 4e-13 49.8 0.1 4e-13 49.8 0.1 2.3 2 0 0 2 2 2 1 FERM central domain PH_11 PF15413.6 KFP18323.1 - 2.3e-06 28.0 1.3 2.3e-06 28.0 1.3 4.9 4 1 0 4 4 4 1 Pleckstrin homology domain PH_6 PF15406.6 KFP18323.1 - 0.0018 18.6 0.0 0.28 11.5 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain DLIC PF05783.11 KFP18324.1 - 5.7e-16 58.4 0.1 5.7e-11 41.9 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Arf PF00025.21 KFP18324.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP18324.1 - 0.0016 18.6 0.0 0.0041 17.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP18324.1 - 0.0028 17.0 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KFP18325.1 - 1.5e-29 103.2 0.0 2.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KFP18325.1 - 3.4e-20 72.4 10.3 6.3e-20 71.5 10.3 1.5 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KFP18325.1 - 6.3e-06 26.2 3.7 0.026 14.4 0.8 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFP18325.1 - 1.8e-05 24.4 0.2 3.6e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFP18325.1 - 2.2e-05 25.1 0.0 3.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFP18325.1 - 2.9e-05 23.6 0.8 0.00079 18.9 0.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFP18325.1 - 0.0036 17.7 0.0 0.0064 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFP18325.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 KFP18325.1 - 0.016 15.1 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KFP18325.1 - 0.038 13.2 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 KFP18325.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KFP18325.1 - 0.078 12.9 0.2 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KFP18325.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 KFP18325.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF5524 PF17662.1 KFP18325.1 - 0.27 10.6 0.0 0.39 10.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5524) ABC_tran PF00005.27 KFP18326.1 - 4.3e-26 92.0 0.0 9.1e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KFP18326.1 - 1.3e-18 67.2 21.6 2.9e-18 66.1 21.6 1.7 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 KFP18326.1 - 0.0016 18.3 6.8 0.018 14.8 0.2 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PPR_2 PF13041.6 KFP18327.1 - 3.8e-34 116.6 25.4 2.9e-07 30.6 0.0 14.4 13 1 3 16 16 16 7 PPR repeat family PPR PF01535.20 KFP18327.1 - 4.9e-26 89.1 41.7 0.0022 18.1 0.0 17.6 19 0 0 19 19 19 6 PPR repeat PPR_1 PF12854.7 KFP18327.1 - 7e-23 80.0 8.4 9e-06 25.3 0.0 8.5 9 0 0 9 9 9 6 PPR repeat PPR_long PF17177.4 KFP18327.1 - 1e-21 77.3 14.4 1.7e-05 24.3 0.0 8.1 5 3 3 8 8 8 5 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KFP18327.1 - 1.8e-21 76.0 18.1 3.9e-08 33.3 0.0 11.2 10 3 4 14 14 14 5 Pentatricopeptide repeat domain ATP13 PF12921.7 KFP18327.1 - 0.00018 21.4 1.6 0.98 9.3 0.0 5.7 6 1 1 7 7 7 1 Mitochondrial ATPase expression TPR_14 PF13428.6 KFP18327.1 - 0.00018 22.0 2.5 1.6e+02 3.6 0.0 7.6 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP18327.1 - 0.0012 19.3 16.0 1.6 9.3 0.5 8.4 10 1 0 10 10 10 1 Tetratricopeptide repeat ECSIT PF06239.11 KFP18327.1 - 0.031 13.4 2.4 6.4 5.8 0.0 4.0 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.6 KFP18327.1 - 0.062 14.0 0.0 15 6.3 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP18327.1 - 0.12 12.6 4.8 14 6.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_lid_8 PF17868.1 KFP18327.1 - 0.21 11.5 1.0 5.6 6.9 0.0 3.6 4 0 0 4 4 3 0 AAA lid domain Fis1_TPR_C PF14853.6 KFP18327.1 - 0.88 9.7 3.1 4.8 7.3 0.0 3.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PP2C PF00481.21 KFP18328.1 - 2.4e-83 279.8 0.0 2.9e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KFP18328.1 - 4.8e-31 107.0 0.1 9e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 KFP18328.1 - 0.0018 17.9 0.0 0.0056 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFP18328.1 - 0.0028 17.6 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Alpha-amylase PF00128.24 KFP18329.1 - 7.6e-78 262.4 1.6 1e-77 262.0 1.6 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 KFP18329.1 - 3.2e-06 26.6 0.3 6.9e-06 25.5 0.3 1.6 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Nup35_RRM_2 PF14605.6 KFP18329.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_70 PF02324.16 KFP18329.1 - 0.074 11.2 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 PsbX PF06596.11 KFP18329.1 - 0.99 9.5 5.2 1.8 8.6 5.2 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Peptidase_S9 PF00326.21 KFP18330.1 - 2.1e-33 115.6 0.0 4.1e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KFP18330.1 - 1.2e-25 90.2 2.2 2.3e-25 89.3 2.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 KFP18330.1 - 0.035 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LRR_8 PF13855.6 KFP18332.1 - 1.1e-84 278.1 52.9 1.8e-15 56.4 0.6 9.5 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFP18332.1 - 5.2e-34 115.7 59.3 5.4e-05 23.5 0.1 11.6 8 3 2 12 12 12 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP18332.1 - 1.2e-32 112.6 11.8 3.9e-10 39.8 1.3 4.6 4 0 0 4 4 4 4 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 KFP18332.1 - 2.1e-26 91.8 108.4 1.1e-06 28.8 5.1 9.5 10 0 0 10 10 8 6 EGF-like domain LRR_9 PF14580.6 KFP18332.1 - 5.5e-23 81.3 18.7 2.8e-06 26.9 1.0 5.4 4 1 1 5 5 5 5 Leucine-rich repeat LRRNT PF01462.18 KFP18332.1 - 3.1e-19 68.2 44.1 6e-09 35.3 3.3 7.3 7 0 0 7 7 7 3 Leucine rich repeat N-terminal domain Laminin_G_2 PF02210.24 KFP18332.1 - 3.4e-18 66.4 0.1 5.5e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFP18332.1 - 1.9e-14 54.0 0.1 3e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 KFP18332.1 - 2.3e-12 47.1 99.0 1.1e-06 29.0 4.9 10.6 11 0 0 11 11 9 6 Human growth factor-like EGF LRRCT PF01463.24 KFP18332.1 - 1e-11 44.4 12.6 0.13 12.9 0.0 6.3 6 0 0 6 6 5 4 Leucine rich repeat C-terminal domain EGF_CA PF07645.15 KFP18332.1 - 0.013 15.6 5.6 0.013 15.6 5.6 9.7 7 1 3 10 10 8 0 Calcium-binding EGF domain LRR_1 PF00560.33 KFP18332.1 - 0.034 14.7 52.9 3.6 8.5 0.0 15.0 15 3 0 15 15 13 0 Leucine Rich Repeat Laminin_G_3 PF13385.6 KFP18332.1 - 0.051 13.7 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily TPKR_C2 PF16920.5 KFP18332.1 - 9.5 6.4 28.9 0.98 9.6 0.2 6.9 7 0 0 7 7 7 0 Tyrosine-protein kinase receptor C2 Ig-like domain Fumble PF03630.14 KFP18333.1 - 3.9e-117 391.1 0.0 4.4e-117 390.9 0.0 1.0 1 0 0 1 1 1 1 Fumble tRNA-synt_1d PF00750.19 KFP18334.1 - 4.6e-158 525.7 0.0 6.1e-158 525.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 KFP18334.1 - 6e-24 84.4 1.5 1.2e-23 83.4 0.2 2.3 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.15 KFP18334.1 - 7.2e-21 74.6 0.2 1.8e-20 73.3 0.2 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Cnn_1N PF07989.11 KFP18334.1 - 0.0082 16.3 0.4 0.039 14.1 0.4 2.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 tRNA-synt_1e PF01406.19 KFP18334.1 - 0.0091 15.4 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KFP18334.1 - 0.13 10.5 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WW PF00397.26 KFP18335.1 - 1.4e-09 37.9 0.2 3.2e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 WW domain C2 PF00168.30 KFP18335.1 - 3.6e-05 24.0 0.0 0.00013 22.2 0.0 2.0 1 1 0 1 1 1 1 C2 domain SPATA6 PF14909.6 KFP18335.1 - 0.082 13.0 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Ten_N PF06484.12 KFP18336.1 - 1.1e-66 226.2 15.4 1.7e-66 225.6 15.4 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.6 KFP18336.1 - 3.9e-31 106.9 0.5 7.1e-31 106.0 0.5 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.13 KFP18336.1 - 2.4e-22 79.0 160.1 8.1e-05 22.9 9.3 9.5 9 0 0 9 9 9 8 EGF-like domain RHS_repeat PF05593.14 KFP18336.1 - 1.2e-13 51.3 33.3 0.00086 19.8 2.2 9.9 9 1 2 11 11 11 4 RHS Repeat NHL PF01436.21 KFP18336.1 - 6.7e-08 32.2 1.2 0.0093 16.0 0.0 5.6 5 0 0 5 5 5 1 NHL repeat CarboxypepD_reg PF13620.6 KFP18336.1 - 0.00015 22.0 0.2 0.00073 19.8 0.0 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF5640 PF18692.1 KFP18336.1 - 0.14 12.2 1.9 3.1 7.9 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5640) Pox_T4_C PF04490.12 KFP18336.1 - 0.18 11.9 1.3 0.49 10.5 1.3 1.7 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus DUF2283 PF10049.9 KFP18336.1 - 1.8 8.8 4.7 22 5.4 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2283) Ten_N PF06484.12 KFP18338.1 - 4.3e-33 115.7 3.1 4.8e-33 115.6 3.1 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region IBR PF01485.21 KFP18339.1 - 7.4e-11 42.1 34.6 4.8e-08 33.1 8.5 3.3 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain SRF-TF PF00319.18 KFP18340.1 - 8.8e-07 28.3 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ig_3 PF13927.6 KFP18341.1 - 4.3e-87 286.8 7.5 1.9e-13 50.8 0.2 7.3 7 0 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KFP18341.1 - 1.3e-85 281.5 0.0 4.2e-14 52.4 0.0 7.3 7 0 0 7 7 7 7 Immunoglobulin I-set domain Pkinase_Tyr PF07714.17 KFP18341.1 - 2.8e-82 275.9 0.0 3.9e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.6 KFP18341.1 - 1.9e-65 217.2 8.3 4.7e-11 42.9 0.1 7.3 7 0 0 7 7 7 7 Immunoglobulin domain ig PF00047.25 KFP18341.1 - 1.9e-46 156.2 3.1 9.6e-08 32.1 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Pkinase PF00069.25 KFP18341.1 - 5.3e-40 137.4 0.0 8.2e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KFP18341.1 - 7.5e-24 84.0 13.2 0.013 15.6 0.4 10.1 7 4 2 9 9 9 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP18341.1 - 5.2e-20 70.8 0.2 0.01 15.4 0.0 7.2 7 0 0 7 7 7 5 Immunoglobulin domain Ig_5 PF16681.5 KFP18341.1 - 4.9e-17 62.1 0.1 0.025 14.9 0.0 7.0 7 1 0 7 7 6 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP18341.1 - 9e-15 54.5 10.2 0.017 15.2 0.1 6.7 7 0 0 7 7 6 5 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP18341.1 - 1.1e-10 41.7 0.8 0.79 10.0 0.0 6.7 7 1 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFP18341.1 - 5.5e-07 29.9 1.3 2.5 8.5 0.0 5.8 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP18341.1 - 6.9e-07 29.2 1.2 3.3 7.8 0.0 6.2 7 0 0 7 7 6 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 KFP18341.1 - 6.9e-06 26.2 0.4 3 8.1 0.0 6.1 6 0 0 6 6 6 1 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFP18341.1 - 4.6e-05 23.4 0.6 0.43 10.6 0.0 4.1 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFP18341.1 - 0.0017 18.1 0.7 2.2 8.1 0.0 4.9 5 1 1 6 6 6 1 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KFP18341.1 - 0.051 13.6 6.9 4.1 7.5 0.0 5.4 7 1 0 7 7 6 0 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFP18341.1 - 0.094 12.9 0.0 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 CD34_antigen PF06365.12 KFP18341.1 - 0.12 11.9 0.1 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family TPR_12 PF13424.6 KFP18342.1 - 8.4e-72 237.5 25.0 1.5e-20 73.3 1.2 5.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFP18342.1 - 6.6e-58 191.1 16.3 1.2e-15 56.8 0.0 7.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFP18342.1 - 2.6e-27 92.8 15.0 4e-06 26.5 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP18342.1 - 1.6e-26 91.0 30.7 1.3e-07 31.1 0.5 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFP18342.1 - 5.6e-19 66.7 27.2 0.00065 19.6 0.4 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFP18342.1 - 2.2e-15 55.5 23.8 0.0014 18.7 0.1 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP18342.1 - 1.3e-14 54.4 6.6 3e-13 49.9 0.5 3.0 3 0 0 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 KFP18342.1 - 1.6e-14 54.3 4.5 0.0015 19.1 1.2 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP18342.1 - 9.1e-13 48.5 7.4 6.9e-05 23.3 0.1 4.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP18342.1 - 1.1e-09 38.3 6.6 5.3 8.1 0.2 6.7 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP18342.1 - 1.8e-09 37.3 12.5 0.04 14.3 0.1 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP18342.1 - 1.8e-07 31.3 12.0 0.0024 18.1 0.5 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KFP18342.1 - 1.8e-07 31.1 2.4 1.8 9.4 0.2 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.20 KFP18342.1 - 0.00011 22.2 3.6 0.037 14.3 0.0 4.6 6 0 0 6 6 3 1 PPR repeat Uso1_p115_C PF04871.13 KFP18342.1 - 0.0025 18.2 11.4 0.0025 18.2 11.4 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region JIP_LZII PF16471.5 KFP18342.1 - 0.0027 17.8 5.3 0.0027 17.8 5.3 2.6 2 1 0 2 2 2 1 JNK-interacting protein leucine zipper II DUF627 PF04781.12 KFP18342.1 - 0.0073 16.3 3.9 0.33 11.0 0.1 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF627) PPR_2 PF13041.6 KFP18342.1 - 0.019 15.2 0.9 2.9 8.2 0.1 3.4 3 0 0 3 3 3 0 PPR repeat family TMF_TATA_bd PF12325.8 KFP18342.1 - 0.02 15.1 10.4 0.02 15.1 10.4 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SHNi-TPR PF10516.9 KFP18342.1 - 0.03 13.8 2.4 5.2 6.6 0.1 4.1 4 0 0 4 4 4 0 SHNi-TPR GHL5 PF14872.6 KFP18342.1 - 0.06 11.4 2.2 0.089 10.8 2.2 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Enolase_N PF03952.16 KFP18342.1 - 0.096 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain Csm1_N PF18504.1 KFP18342.1 - 0.15 12.4 9.0 0.72 10.2 8.4 2.6 1 1 0 1 1 1 0 Csm1 N-terminal domain WbqC PF08889.11 KFP18342.1 - 0.22 11.4 2.9 10 5.9 0.0 3.6 3 1 1 4 4 4 0 WbqC-like protein family RPN7 PF10602.9 KFP18342.1 - 0.24 11.1 7.6 2 8.1 0.0 3.9 3 1 1 4 4 3 0 26S proteasome subunit RPN7 COG2 PF06148.11 KFP18342.1 - 0.36 10.9 8.5 0.23 11.6 5.8 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 KFP18342.1 - 0.54 9.5 9.8 1.2 8.4 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RasGAP_C PF03836.15 KFP18342.1 - 0.91 9.7 11.2 1.3 9.1 9.6 2.1 1 1 0 1 1 1 0 RasGAP C-terminus Spc7 PF08317.11 KFP18342.1 - 1.2 8.0 19.0 2.3 7.0 19.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3972 PF13118.6 KFP18342.1 - 2.2 8.7 11.4 1.3e+02 3.0 11.4 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) SOGA PF11365.8 KFP18342.1 - 3.2 9.0 17.2 25 6.1 10.8 3.8 1 1 1 2 2 2 0 Protein SOGA FapA PF03961.13 KFP18342.1 - 4.1 5.9 9.0 6.7 5.2 9.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_11 PF13414.6 KFP18342.1 - 4.4 7.1 19.3 0.88 9.3 0.2 5.8 6 0 0 6 6 6 0 TPR repeat TPR_6 PF13174.6 KFP18342.1 - 6.3 7.7 17.6 1.2 9.9 0.3 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat ANAPC10 PF03256.16 KFP18344.1 - 0.025 14.2 0.0 0.057 13.0 0.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Pacs-1 PF10254.9 KFP18345.1 - 1.4e-193 643.5 0.2 2.4e-193 642.7 0.0 1.5 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein hNIFK_binding PF12196.8 KFP18345.1 - 0.21 11.1 1.2 0.59 9.7 1.2 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK CECR6_TMEM121 PF14997.6 KFP18346.1 - 2.2e-61 207.1 12.8 2.2e-61 207.1 12.8 1.5 2 0 0 2 2 2 1 CECR6/TMEM121 family DUF5083 PF16890.5 KFP18346.1 - 0.0045 16.8 1.9 0.0045 16.8 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5083) DUF565 PF04483.12 KFP18346.1 - 4.3 8.0 7.2 19 5.9 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF565) Kelch_6 PF13964.6 KFP18347.1 - 7.5e-44 146.7 10.1 2e-09 37.4 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFP18347.1 - 2.1e-40 135.2 11.4 3.5e-07 29.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KFP18347.1 - 1.2e-39 133.6 7.8 2.9e-08 33.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFP18347.1 - 3.4e-34 116.3 12.4 3.6e-06 26.8 0.3 6.5 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 KFP18347.1 - 1.6e-30 104.9 20.0 6.1e-08 32.6 0.2 7.7 5 3 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP18347.1 - 7.3e-29 99.5 10.3 3.5e-06 27.2 0.2 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain B56 PF01603.20 KFP18348.1 - 1.1e-190 634.0 5.7 1.4e-190 633.7 5.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Stm1_N PF09598.10 KFP18348.1 - 3 8.8 8.0 8.3 7.3 8.0 1.8 1 0 0 1 1 1 0 Stm1 Hydrolase_4 PF12146.8 KFP18350.1 - 2e-17 63.3 0.0 7.6e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP18350.1 - 1.4e-15 57.6 0.4 1.9e-13 50.7 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP18350.1 - 2e-09 38.4 0.8 6.3e-09 36.7 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFP18350.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFP18350.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KFP18350.1 - 0.0094 15.4 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFP18350.1 - 0.034 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KFP18350.1 - 0.04 13.7 0.0 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 KFP18350.1 - 0.1 11.4 0.0 0.22 10.3 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KFP18350.1 - 0.15 11.0 0.0 0.87 8.4 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme LIP PF03583.14 KFP18350.1 - 0.22 10.8 0.0 0.48 9.7 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Phosphorylase PF00343.20 KFP18351.1 - 0 1150.4 0.0 0 1150.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TPR_22 PF18833.1 KFP18351.1 - 0.00019 21.5 0.1 0.00046 20.3 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat GDA1_CD39 PF01150.17 KFP18352.1 - 7.1e-73 245.7 0.0 5.4e-72 242.8 0.0 2.0 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KFP18352.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.4 1 1 0 1 1 1 0 Ppx/GppA phosphatase family Homeodomain PF00046.29 KFP18353.1 - 2e-10 40.3 8.8 3.4e-05 23.6 0.2 2.4 2 0 0 2 2 2 2 Homeodomain Methyltransf_31 PF13847.6 KFP18354.1 - 8e-08 32.2 0.0 1.9e-07 31.0 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP18354.1 - 2.3e-06 28.2 0.0 4.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP18354.1 - 5.6e-06 27.0 0.0 9.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP18354.1 - 2e-05 25.1 0.0 3.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP18354.1 - 0.0077 16.1 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF3456 PF11938.8 KFP18355.1 - 7.7e-29 101.2 0.2 8.5e-29 101.1 0.2 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP RNA_pol_Rpb2_6 PF00562.28 KFP18356.1 - 2e-116 389.3 0.0 5.7e-116 387.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KFP18356.1 - 5.5e-27 93.7 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 KFP18356.1 - 1.1e-23 83.9 0.1 2.1e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFP18356.1 - 7.7e-21 74.3 0.0 1.7e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 KFP18356.1 - 1.2e-18 66.8 0.0 2.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KFP18356.1 - 1.1e-11 44.7 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 PBP_GOBP PF01395.22 KFP18356.1 - 0.24 11.5 1.0 0.52 10.5 1.0 1.5 1 0 0 1 1 1 0 PBP/GOBP family TTL PF03133.15 KFP18357.1 - 3.4e-68 229.9 0.1 9.8e-68 228.4 0.1 1.6 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFP18357.1 - 2.2e-07 30.4 0.2 3.7e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFP18357.1 - 0.021 14.1 0.0 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp EntA_Immun PF08951.10 KFP18357.1 - 0.044 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Enterocin A Immunity Sugar_tr PF00083.24 KFP18358.1 - 2e-33 116.0 22.0 2.7e-33 115.5 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP18358.1 - 1.8e-30 106.0 28.6 2.4e-30 105.7 28.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFP18358.1 - 0.0051 15.3 6.4 0.0093 14.4 6.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFP18358.1 - 0.0052 15.4 9.1 0.0052 15.4 9.1 2.9 2 1 0 3 3 3 1 MFS/sugar transport protein Pkinase PF00069.25 KFP18359.1 - 4.5e-32 111.5 0.0 6.9e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18359.1 - 1.1e-19 70.7 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP18359.1 - 0.04 12.7 0.0 0.12 11.1 0.0 1.8 1 0 0 1 1 1 0 Fungal protein kinase AMP-binding PF00501.28 KFP18360.1 - 3.4e-92 309.3 0.1 4.1e-92 309.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP18360.1 - 3.9e-23 82.2 1.2 2e-22 80.0 0.4 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Str_synth PF03088.16 KFP18361.1 - 1.5e-29 101.9 0.1 7.3e-29 99.7 0.0 2.2 2 1 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 KFP18361.1 - 3.9e-15 56.1 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KFP18361.1 - 0.00014 21.8 0.1 0.18 11.9 0.0 4.6 5 0 0 5 5 5 1 NHL repeat Arylesterase PF01731.20 KFP18361.1 - 0.0015 18.7 0.2 0.22 11.7 0.0 3.4 4 2 0 4 4 4 1 Arylesterase PQQ_3 PF13570.6 KFP18361.1 - 0.025 15.1 0.0 3.9 8.1 0.0 3.5 3 1 0 3 3 3 0 PQQ-like domain Cystatin PF00031.21 KFP18362.1 - 5.8e-16 58.5 0.0 6.5e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KFP18362.1 - 0.00024 21.4 0.0 0.00033 21.0 0.0 1.2 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor N-glycanase_N PF09112.10 KFP18362.1 - 0.025 14.4 0.2 0.07 12.9 0.2 1.7 1 1 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Cathelicidins PF00666.17 KFP18362.1 - 0.086 13.2 0.3 0.14 12.5 0.2 1.5 1 1 1 2 2 2 0 Cathelicidin YmzC PF14157.6 KFP18362.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 YmzC-like protein CD225 PF04505.12 KFP18363.1 - 1.4e-18 66.8 0.1 2.2e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Cofilin_ADF PF00241.20 KFP18364.1 - 2.1e-32 111.5 0.2 2.6e-32 111.1 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rib_recp_KP_reg PF05104.12 KFP18365.1 - 4.2e-30 105.8 45.3 4.2e-30 105.8 45.3 7.6 3 2 5 8 8 8 1 Ribosome receptor lysine/proline rich region ABC_export PF16962.5 KFP18365.1 - 0.058 11.8 0.2 0.087 11.3 0.2 1.2 1 0 0 1 1 1 0 Putative ABC exporter DUF3899 PF13038.6 KFP18365.1 - 4.7 7.8 4.8 1.8 9.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) PX PF00787.24 KFP18366.1 - 4.3e-19 68.6 4.8 5e-19 68.4 0.3 2.8 3 1 0 3 3 3 1 PX domain Vps5 PF09325.10 KFP18366.1 - 5.5e-17 62.1 18.8 8.2e-16 58.3 13.9 2.5 2 1 0 2 2 2 1 Vps5 C terminal like Glyco_hydro_97 PF10566.9 KFP18366.1 - 0.11 11.8 0.2 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 LcrG PF07216.12 KFP18366.1 - 0.13 12.2 0.4 8.1 6.4 0.0 3.0 3 0 0 3 3 3 0 LcrG protein zf-C2H2 PF00096.26 KFP18367.1 - 2.8e-18 65.3 26.3 4.5e-05 23.7 2.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP18367.1 - 4.6e-18 64.7 23.2 1.8e-09 37.6 0.6 5.3 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP18367.1 - 4.6e-12 45.7 25.0 0.00026 21.6 1.4 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP18367.1 - 5.7e-08 33.5 13.5 4.6e-06 27.3 0.5 3.0 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFP18367.1 - 5.9e-06 26.4 10.4 0.38 11.1 0.5 3.8 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP18367.1 - 3.1e-05 24.2 15.8 0.0008 19.7 2.4 4.5 3 1 1 4 4 4 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KFP18367.1 - 0.00017 21.2 0.0 0.00017 21.2 0.0 2.9 2 1 1 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KFP18367.1 - 0.00053 19.7 20.3 0.12 12.1 0.2 5.3 4 2 1 5 5 5 2 C2H2-type zinc-finger domain FYVE PF01363.21 KFP18367.1 - 0.005 16.9 20.0 15 5.8 20.0 2.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFP18367.1 - 0.063 13.1 1.2 0.063 13.1 1.2 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_12 PF18658.1 KFP18367.1 - 0.084 12.5 0.0 0.084 12.5 0.0 3.4 1 1 2 3 3 3 0 Zinc-finger C2H2-type DUF2256 PF10013.9 KFP18367.1 - 0.16 12.1 6.7 5.9 7.1 0.4 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KFP18367.1 - 0.18 11.4 12.6 4.1 7.1 0.1 4.1 4 0 0 4 4 4 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 KFP18367.1 - 0.36 11.6 11.8 0.55 11.0 1.4 2.3 1 1 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 KFP18367.1 - 0.42 10.8 17.5 4.7 7.4 0.4 4.4 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KFP18367.1 - 0.53 10.6 16.4 2.4 8.6 1.1 3.8 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.18 KFP18367.1 - 0.65 10.1 9.8 35 4.5 0.2 4.2 4 0 0 4 4 4 0 XPA protein N-terminal A2L_zn_ribbon PF08792.10 KFP18367.1 - 0.67 9.7 0.1 0.67 9.7 0.1 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain C1_1 PF00130.22 KFP18367.1 - 0.96 9.4 16.8 0.93 9.4 6.0 3.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFP18367.1 - 1.1 8.9 10.7 8.5 6.1 0.6 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KFP18367.1 - 2.2 8.4 27.6 0.77 9.8 3.3 3.7 4 0 0 4 4 3 0 C2H2-type zinc finger ADK_lid PF05191.14 KFP18367.1 - 2.6 8.1 11.2 0.37 10.8 1.6 3.4 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-dskA_traR PF01258.17 KFP18367.1 - 2.7 8.0 7.9 7.9 6.5 0.0 3.7 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Acetyltransf_1 PF00583.25 KFP18368.1 - 6e-10 39.4 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP18368.1 - 1.3e-09 38.0 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP18368.1 - 9e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP18368.1 - 7.1e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFP18368.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFP18368.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase zf_UBZ PF18439.1 KFP18368.1 - 1.4 8.6 4.1 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFP18369.1 - 1.7e-18 66.4 38.7 3.4e-10 39.8 13.1 3.8 4 0 0 4 4 4 3 Double zinc ribbon Fn3_assoc PF13287.6 KFP18369.1 - 5.7e-16 58.4 0.1 1.1e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.6 KFP18369.1 - 6.6e-15 54.9 0.1 1.1e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_2 PF12796.7 KFP18369.1 - 1.6e-09 38.2 0.1 5.7e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP18369.1 - 3.8e-08 33.4 0.5 0.0051 17.2 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP18369.1 - 6.3e-06 26.1 0.0 0.51 11.1 0.1 4.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KFP18369.1 - 6.7e-06 26.6 0.1 0.099 13.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) zinc_ribbon_2 PF13240.6 KFP18369.1 - 2.4e-05 23.9 13.4 0.0005 19.7 1.3 6.0 5 1 0 5 5 5 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 KFP18369.1 - 0.0039 16.5 1.9 0.0039 16.5 1.9 5.6 5 1 0 5 5 5 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFP18369.1 - 0.17 12.6 33.5 0.76 10.6 0.5 5.1 4 1 0 4 4 4 0 zinc-ribbon family zf-RanBP PF00641.18 KFP18369.1 - 2.6 7.4 29.4 0.8 9.1 0.7 5.4 5 0 0 5 5 5 0 Zn-finger in Ran binding protein and others RNA_pol_Rpc34 PF05158.12 KFP18370.1 - 2.7e-103 345.9 0.3 3.3e-103 345.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.19 KFP18370.1 - 0.00017 21.4 0.6 0.01 15.7 0.1 2.9 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 KFP18370.1 - 0.0035 18.0 0.9 1.2 9.9 0.0 3.3 3 0 0 3 3 3 1 Replication protein A C terminal TFIIE_alpha PF02002.17 KFP18370.1 - 0.048 13.5 0.4 0.12 12.2 0.4 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit Sec23_trunk PF04811.15 KFP18371.1 - 1.9e-72 243.8 0.0 2.8e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFP18371.1 - 2.2e-31 108.4 0.0 4.7e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFP18371.1 - 1.6e-26 92.1 0.1 5.2e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFP18371.1 - 4.3e-16 58.6 0.0 1.5e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KFP18371.1 - 3.5e-15 55.8 5.9 6.3e-15 54.9 5.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger APP_E2 PF12925.7 KFP18371.1 - 0.029 14.1 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Tyr_Deacylase PF02580.16 KFP18372.1 - 3.7e-44 150.8 0.0 4.5e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase 7tm_4 PF13853.6 KFP18374.1 - 1.2e-47 163.0 9.3 1.4e-47 162.8 9.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP18374.1 - 6.7e-31 107.6 9.9 9.3e-31 107.1 9.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP18374.1 - 4.2e-06 26.3 7.1 6e-06 25.8 6.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP18374.1 - 0.00027 20.7 3.8 0.00027 20.7 3.8 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP18375.1 - 3.8e-42 144.9 15.0 4.5e-42 144.7 15.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP18375.1 - 9e-31 107.2 14.1 1.4e-30 106.5 14.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP18375.1 - 0.016 14.6 15.1 0.09 12.1 15.0 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx CHGN PF05679.16 KFP18376.1 - 2.7e-171 570.9 0.1 3.1e-171 570.7 0.1 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 KFP18376.1 - 1.3e-06 28.0 0.2 3.5e-06 26.6 0.0 1.8 2 1 0 2 2 2 1 Fringe-like DUF4203 PF13886.6 KFP18377.1 - 1.3e-31 109.9 25.2 1.8e-16 60.4 10.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) MTABC_N PF16185.5 KFP18377.1 - 0.031 13.8 10.9 0.051 13.1 10.9 1.3 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region SlyX PF04102.12 KFP18377.1 - 1 10.0 4.4 2.1 9.0 4.4 1.4 1 0 0 1 1 1 0 SlyX TGF_beta PF00019.20 KFP18378.1 - 1.7e-15 57.9 0.8 1.9e-14 54.5 0.8 2.3 1 1 0 1 1 1 1 Transforming growth factor beta like domain Connexin PF00029.19 KFP18379.1 - 1.6e-89 299.7 1.2 1.3e-88 296.7 1.2 1.9 1 1 0 1 1 1 1 Connexin LIP1 PF15904.5 KFP18380.1 - 1.3e-35 121.6 1.9 3.3e-35 120.3 1.9 1.7 1 0 0 1 1 1 1 LKB1 serine/threonine kinase interacting protein 1 LRR_4 PF12799.7 KFP18380.1 - 3.8e-11 43.0 19.5 2.6e-06 27.7 2.0 4.7 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP18380.1 - 4.1e-11 42.5 16.2 1.3e-05 24.8 4.1 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KFP18380.1 - 3.8e-06 26.5 2.5 1.1e-05 25.0 2.4 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KFP18380.1 - 0.39 10.9 12.8 0.73 10.0 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 KFP18380.1 - 1.7 9.5 20.5 37 5.4 0.1 7.5 7 1 0 7 7 7 0 Leucine Rich Repeat HCO3_cotransp PF00955.21 KFP18381.1 - 7e-204 678.4 23.7 1.5e-123 413.3 9.5 2.3 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 KFP18381.1 - 2.5e-106 355.4 0.5 2.5e-106 355.4 0.5 2.6 3 0 0 3 3 3 1 Band 3 cytoplasmic domain BUD22 PF09073.10 KFP18381.1 - 5.5e-06 26.0 4.3 5.5e-06 26.0 4.3 2.0 2 1 1 3 3 3 1 BUD22 PTS_EIIA_2 PF00359.22 KFP18381.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 NPR3 PF03666.13 KFP18381.1 - 0.011 14.6 9.2 0.043 12.6 7.7 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Paf1 PF03985.13 KFP18381.1 - 0.84 8.6 16.5 1.9 7.4 16.5 1.6 1 0 0 1 1 1 0 Paf1 Lectin_C PF00059.21 KFP18382.1 - 6.3e-136 445.1 73.1 2.7e-19 69.9 0.2 11.8 12 1 0 12 12 12 10 Lectin C-type domain fn2 PF00040.19 KFP18382.1 - 7.9e-15 54.9 8.0 9.6e-15 54.6 5.6 2.6 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFP18382.1 - 4.4e-10 39.5 22.4 0.051 13.2 0.0 9.5 10 1 0 10 10 10 5 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFP18382.1 - 0.001 19.4 12.8 27 5.2 0.0 8.9 10 1 0 10 10 10 1 Extracellular link domain Ricin_B_lectin PF00652.22 KFP18382.1 - 0.0058 16.9 0.8 0.0058 16.9 0.8 3.8 4 0 0 4 4 4 1 Ricin-type beta-trefoil lectin domain Cytochrom_B561 PF03188.16 KFP18382.1 - 0.21 11.7 1.8 0.43 10.7 1.0 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Lectin_C PF00059.21 KFP18383.1 - 7.8e-124 406.2 48.0 4.2e-18 66.1 0.5 8.6 8 0 0 8 8 8 8 Lectin C-type domain fn2 PF00040.19 KFP18383.1 - 4.4e-15 55.7 14.0 4.4e-15 55.7 14.0 2.6 2 0 0 2 2 2 1 Fibronectin type II domain UL45 PF05473.12 KFP18383.1 - 3.4e-12 46.4 8.2 0.001 18.8 0.2 7.2 5 3 1 6 6 6 4 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KFP18383.1 - 5.3e-06 26.7 9.7 0.89 10.0 0.0 7.7 7 0 0 7 7 7 1 Extracellular link domain Chordopox_A33R PF05966.12 KFP18383.1 - 0.00031 20.1 5.0 0.12 11.7 0.1 4.5 5 0 0 5 5 5 2 Chordopoxvirus A33R protein rhaM PF05336.13 KFP18383.1 - 0.049 13.7 0.8 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 L-rhamnose mutarotase Integrin_beta PF00362.18 KFP18384.1 - 5.1e-110 367.0 0.0 7.8e-110 366.4 0.0 1.3 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 KFP18384.1 - 5.1e-19 67.7 0.4 8.3e-19 67.0 0.4 1.3 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain PSI_integrin PF17205.3 KFP18384.1 - 2e-14 53.0 7.2 2e-14 53.0 7.2 5.1 4 1 2 6 6 6 1 Integrin plexin domain Integrin_B_tail PF07965.12 KFP18384.1 - 1.9e-13 50.7 5.0 1.9e-13 50.7 5.0 4.1 3 1 2 6 6 6 1 Integrin beta tail domain I-EGF_1 PF18372.1 KFP18384.1 - 7.7e-11 41.9 7.8 7.7e-11 41.9 7.8 6.8 8 0 0 8 8 8 4 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KFP18384.1 - 1e-05 25.8 40.0 0.00017 21.9 18.7 8.3 8 2 2 10 10 10 4 EGF-like domain RRM_1 PF00076.22 KFP18385.1 - 4.5e-33 112.9 0.0 2.9e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KFP18385.1 - 0.00075 19.7 0.0 0.95 9.7 0.0 2.3 2 0 0 2 2 2 2 BRCA1-associated protein 2 RRM_7 PF16367.5 KFP18385.1 - 0.14 12.3 0.0 15 5.8 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif JAB PF01398.21 KFP18387.1 - 6.5e-33 113.2 0.0 8.9e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFP18387.1 - 9.5e-07 28.6 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Ras PF00071.22 KFP18388.1 - 2.8e-42 144.0 0.0 3.4e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP18388.1 - 6.7e-29 100.5 0.0 9.3e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP18388.1 - 5.2e-10 39.0 0.0 6.5e-10 38.7 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP18388.1 - 1e-06 28.3 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KFP18388.1 - 0.0028 17.1 0.0 0.0096 15.3 0.0 1.9 1 1 1 2 2 2 1 Bacterial TniB protein MMR_HSR1 PF01926.23 KFP18388.1 - 0.0048 17.0 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFP18388.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFP18388.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KFP18388.1 - 0.047 13.4 0.0 0.66 9.7 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFP18388.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7tm_3 PF00003.22 KFP18389.1 - 9.3e-58 195.7 24.8 1.3e-57 195.2 24.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 KFP18389.1 - 6.2e-46 157.1 0.0 8.7e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GluR_Homer-bdg PF10606.9 KFP18389.1 - 1.6e-20 73.0 12.1 5.3e-20 71.4 12.1 2.0 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.14 KFP18389.1 - 8.1e-16 57.7 13.1 1.6e-15 56.8 13.1 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 KFP18389.1 - 0.086 13.2 0.5 0.29 11.5 0.5 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5438) Tyrosinase PF00264.20 KFP18390.1 - 1.5e-41 143.1 0.9 1.5e-41 143.1 0.9 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KFP18390.1 - 0.18 12.0 13.0 0.092 12.9 8.5 2.4 2 1 0 2 2 2 0 Laminin EGF domain Ferric_reduct PF01794.19 KFP18391.1 - 1.5e-23 83.3 5.2 1.5e-23 83.3 5.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFP18391.1 - 2.5e-22 79.7 0.0 9e-21 74.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFP18391.1 - 2.4e-15 56.5 0.0 5.3e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFP18391.1 - 0.13 13.0 0.0 0.42 11.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ni_hydr_CYTB PF01292.20 KFP18391.1 - 2.2 7.8 8.7 3.7 7.1 0.5 2.3 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 ORMDL PF04061.14 KFP18391.1 - 9.2 6.1 8.6 1.9 8.3 2.8 2.4 2 0 0 2 2 2 0 ORMDL family TFR_dimer PF04253.15 KFP18392.1 - 1.3e-36 125.3 0.1 2.4e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFP18392.1 - 5.1e-18 65.5 0.0 1.8e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFP18392.1 - 1e-14 54.3 0.0 2.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 PA domain PPR_3 PF13812.6 KFP18392.1 - 0.0076 16.3 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain TFR_dimer PF04253.15 KFP18393.1 - 5e-36 123.5 0.0 1.1e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFP18393.1 - 1e-19 71.0 0.0 1e-18 67.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KFP18393.1 - 8.9e-13 48.1 0.0 2.2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 PA domain CHORD PF04968.12 KFP18394.1 - 7.4e-47 157.9 18.6 2e-26 92.4 8.3 2.9 3 0 0 3 3 3 2 CHORD CS PF04969.16 KFP18394.1 - 3.3e-13 50.4 0.1 6.6e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 CS domain Histone PF00125.24 KFP18395.1 - 1.3e-18 67.6 0.0 1.7e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFP18395.1 - 1.5e-18 66.2 0.9 2.7e-18 65.4 0.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFP18395.1 - 7.9e-05 22.9 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L27A PF00828.19 KFP18395.1 - 0.043 14.5 0.1 0.05 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Histone_H2A_C PF16211.5 KFP18396.1 - 2.7e-20 71.8 1.1 4e-20 71.2 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFP18396.1 - 4.1e-11 43.4 0.0 5.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFP18397.1 - 2.7e-20 71.8 1.1 3.9e-20 71.3 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFP18397.1 - 4.3e-11 43.3 0.0 5.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFP18398.1 - 2.4e-20 71.9 1.1 3.6e-20 71.4 1.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFP18398.1 - 4.2e-11 43.3 0.0 5.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ApoL PF05461.11 KFP18399.1 - 3.7e-13 49.5 2.7 3.7e-13 49.5 2.7 1.6 2 0 0 2 2 2 1 Apolipoprotein L SseC PF04888.12 KFP18399.1 - 0.0013 18.4 1.6 0.79 9.3 0.0 2.0 1 1 0 2 2 2 2 Secretion system effector C (SseC) like family Takusan PF04822.13 KFP18399.1 - 1 9.3 3.6 0.5 10.3 0.3 2.1 3 0 0 3 3 3 0 Takusan DEAD PF00270.29 KFP18400.1 - 3.5e-48 163.7 0.2 5.5e-48 163.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP18400.1 - 2.6e-32 111.5 0.3 2.5e-31 108.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP18400.1 - 3.6e-06 27.1 0.0 7.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFP18400.1 - 0.0072 16.0 0.0 0.029 14.0 0.0 2.0 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 KFP18400.1 - 0.038 14.3 0.1 0.078 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain 7tm_3 PF00003.22 KFP18401.1 - 3.3e-26 92.5 31.1 4.3e-26 92.1 31.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Tetraspanin PF00335.20 KFP18401.1 - 0.00036 20.3 3.6 0.00036 20.3 3.6 2.5 2 0 0 2 2 2 1 Tetraspanin family DUF1345 PF07077.11 KFP18401.1 - 0.062 13.0 10.7 0.34 10.6 6.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) TctB PF07331.11 KFP18401.1 - 0.2 11.9 28.4 0.031 14.5 11.9 2.8 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1772 PF08592.11 KFP18401.1 - 0.24 11.7 12.6 0.29 11.4 0.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) 7TMR-DISM_7TM PF07695.11 KFP18401.1 - 0.69 9.8 33.2 2.5 7.9 33.1 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4271 PF14093.6 KFP18401.1 - 1.4 8.8 30.6 0.24 11.3 11.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) DUF4131 PF13567.6 KFP18401.1 - 1.4 8.5 24.2 0.48 10.1 10.7 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SOUL PF04832.12 KFP18402.1 - 2.5e-36 125.4 0.0 2.7e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein DUF1409 PF07197.12 KFP18403.1 - 0.0076 16.1 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1409) I_LWEQ PF01608.17 KFP18403.1 - 0.038 14.2 0.2 0.057 13.6 0.2 1.2 1 0 0 1 1 1 0 I/LWEQ domain HxlR PF01638.17 KFP18403.1 - 0.054 13.3 1.2 0.21 11.4 0.6 2.2 2 1 1 3 3 3 0 HxlR-like helix-turn-helix PQQ_2 PF13360.6 KFP18404.1 - 6.3e-08 32.5 0.1 0.00056 19.6 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain VCBS PF13517.6 KFP18404.1 - 7.3e-06 26.5 0.1 0.23 12.1 0.0 3.1 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KFP18404.1 - 1.4e-05 25.1 2.5 0.047 13.8 0.3 2.8 2 0 0 2 2 2 2 FG-GAP repeat GSG-1 PF07803.11 KFP18405.1 - 8.7e-50 167.5 0.0 1.6e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 GSG1-like protein PMP22_Claudin PF00822.20 KFP18405.1 - 1.3e-07 31.6 2.6 1.3e-07 31.6 2.6 2.3 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP18405.1 - 0.00079 19.2 7.9 0.00079 19.2 7.9 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 KFP18405.1 - 0.0046 16.9 2.5 0.07 13.1 2.0 2.2 2 0 0 2 2 2 1 Tight junction protein, Claudin-like Clc-like PF07062.12 KFP18405.1 - 0.016 14.6 5.7 0.87 9.0 0.0 2.5 2 1 0 2 2 2 0 Clc-like PMP22_Claudin PF00822.20 KFP18406.1 - 2.5e-43 147.8 21.5 2.8e-43 147.7 21.5 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP18406.1 - 0.0041 16.9 17.3 0.0041 16.9 17.3 3.0 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction DUF1616 PF07760.11 KFP18406.1 - 0.02 14.3 1.8 0.037 13.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF4064 PF13273.6 KFP18406.1 - 0.02 15.1 19.9 0.13 12.5 10.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Amastin PF07344.11 KFP18406.1 - 0.053 13.4 25.2 0.1 12.5 23.4 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF998 PF06197.13 KFP18406.1 - 0.061 12.9 12.0 0.023 14.3 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) 7TMR-DISM_7TM PF07695.11 KFP18406.1 - 5 7.0 29.1 8.9 6.2 3.4 2.9 1 1 1 2 2 2 0 7TM diverse intracellular signalling PalH PF08733.10 KFP18406.1 - 7 5.6 20.3 0.13 11.2 9.5 2.0 2 0 0 2 2 2 0 PalH/RIM21 Claudin_3 PF06653.11 KFP18406.1 - 7.6 6.5 24.0 15 5.5 24.0 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like EF1_GNE PF00736.19 KFP18407.1 - 1.2e-38 131.1 1.1 2e-38 130.4 1.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFP18407.1 - 1.4e-13 51.0 8.4 1.4e-13 51.0 8.4 2.5 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region MinC_N PF05209.13 KFP18407.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain YL1 PF05764.13 KFP18407.1 - 0.16 12.0 5.7 0.19 11.8 5.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein NAPRTase_C PF17956.1 KFP18408.1 - 9.7e-25 87.2 0.0 1.6e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 KFP18408.1 - 2e-10 41.2 0.0 3.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KFP18408.1 - 0.00011 21.9 0.0 0.0069 16.0 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Ras PF00071.22 KFP18410.1 - 2.9e-14 53.0 0.1 4.1e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP18410.1 - 0.019 15.2 0.0 0.047 13.9 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFP18410.1 - 0.036 14.0 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Trigger_C PF05698.14 KFP18410.1 - 0.071 13.1 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus C5HCH PF17982.1 KFP18412.1 - 3.6e-23 81.4 10.4 3.6e-23 81.4 10.4 5.1 3 1 1 4 4 4 1 NSD Cys-His rich domain SET PF00856.28 KFP18412.1 - 1.3e-20 74.4 1.5 1.3e-19 71.2 0.9 2.8 3 1 0 3 3 3 1 SET domain PWWP PF00855.17 KFP18412.1 - 8.8e-19 67.7 0.4 2e-18 66.6 0.4 1.6 1 0 0 1 1 1 1 PWWP domain AWS PF17907.1 KFP18412.1 - 1.4e-17 63.4 7.4 1.4e-17 63.4 7.4 5.7 7 1 0 7 7 7 1 AWS domain PHD PF00628.29 KFP18412.1 - 1.1e-14 54.0 70.0 2e-06 27.6 10.6 6.7 4 2 2 6 6 6 4 PHD-finger PHD_2 PF13831.6 KFP18412.1 - 5.8e-06 25.8 37.4 0.00035 20.0 1.9 5.9 5 1 0 5 5 5 3 PHD-finger Pkinase_Tyr PF07714.17 KFP18414.1 - 7.5e-104 346.6 0.0 9.9e-104 346.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP18414.1 - 2.3e-44 151.8 0.0 3.4e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 KFP18414.1 - 8.1e-36 122.5 0.0 4.4e-13 49.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP18414.1 - 1.6e-35 121.1 0.0 2.4e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18414.1 - 4.8e-28 97.3 0.1 5.6e-10 39.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP18414.1 - 3.3e-26 91.3 0.0 3e-10 40.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP18414.1 - 1.3e-13 51.1 0.3 0.039 14.1 0.1 5.2 3 2 0 3 3 3 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP18414.1 - 2e-06 28.1 0.0 3.6 8.1 0.0 3.9 3 0 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP18414.1 - 6.1e-06 25.7 0.0 0.79 9.3 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFP18414.1 - 0.00038 20.6 0.0 1.1 9.6 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP18414.1 - 0.0029 17.6 0.0 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain FGFR3_TM PF18123.1 KFP18414.1 - 0.0088 15.5 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain DUF5412 PF17428.2 KFP18414.1 - 0.026 14.4 0.0 0.087 12.7 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5412) Haspin_kinase PF12330.8 KFP18414.1 - 0.044 12.7 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain C2-set_2 PF08205.12 KFP18414.1 - 0.058 13.5 0.0 0.44 10.7 0.0 2.4 3 0 0 3 3 2 0 CD80-like C2-set immunoglobulin domain Pkinase_fungal PF17667.1 KFP18414.1 - 0.073 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFP18414.1 - 0.11 11.8 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like zf-met PF12874.7 KFP18415.1 - 1.1e-13 51.1 16.4 3.4e-07 30.4 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP18415.1 - 4.4e-09 36.4 8.5 0.00012 22.3 1.8 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP18415.1 - 0.001 19.3 8.0 0.12 12.7 0.7 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) CTU2 PF10288.9 KFP18415.1 - 0.002 18.4 5.6 0.036 14.3 4.4 2.1 1 1 1 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 zf-U1 PF06220.12 KFP18415.1 - 0.0076 16.0 9.7 0.14 12.0 1.5 3.2 3 0 0 3 3 3 2 U1 zinc finger zf-RING_UBOX PF13445.6 KFP18415.1 - 0.0085 16.1 0.3 0.64 10.1 0.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Vps39_2 PF10367.9 KFP18415.1 - 0.041 14.3 1.2 4.2 7.9 0.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-DBF PF07535.12 KFP18415.1 - 0.14 12.3 4.1 0.8 9.9 0.9 2.5 2 0 0 2 2 2 0 DBF zinc finger zf_C2H2_6 PF18450.1 KFP18415.1 - 0.17 11.6 0.6 0.17 11.6 0.6 2.1 2 0 0 2 2 2 0 Zinc Finger domain zf-SCNM1 PF15803.5 KFP18415.1 - 0.44 10.2 3.5 1.9 8.2 0.4 3.2 3 1 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_4 PF13894.6 KFP18415.1 - 0.82 10.7 12.1 0.74 10.8 1.2 3.1 3 2 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP18415.1 - 1.1 9.9 11.8 0.65 10.6 1.0 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KFP18415.1 - 1.5 8.8 4.0 1.2 9.0 0.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) RAP80_UIM PF18282.1 KFP18416.1 - 4.7e-34 115.9 11.3 4.7e-34 115.9 11.3 2.4 3 0 0 3 3 3 1 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KFP18416.1 - 0.0042 16.9 11.0 0.034 14.0 2.3 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-WRNIP1_ubi PF18279.1 KFP18416.1 - 0.06 14.0 0.1 0.29 11.9 0.0 2.3 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Carboxyl_trans PF01039.22 KFP18416.1 - 0.3 9.7 0.8 0.57 8.7 0.0 1.7 2 0 0 2 2 2 0 Carboxyl transferase domain SIR4_SID PF16991.5 KFP18416.1 - 4.5 7.3 6.7 1.4 8.9 3.1 1.9 2 0 0 2 2 2 0 Sir4 SID domain TSP_C PF05735.12 KFP18417.1 - 8.8e-70 234.7 1.8 1.3e-69 234.2 1.8 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFP18417.1 - 4.5e-57 189.4 138.8 7.4e-12 44.7 15.4 10.4 8 2 2 10 10 10 8 Thrombospondin type 3 repeat TSP_1 PF00090.19 KFP18417.1 - 1.4e-46 156.4 56.2 4.6e-17 62.0 8.5 5.0 4 0 0 4 4 4 3 Thrombospondin type 1 domain VWC PF00093.18 KFP18417.1 - 4e-13 49.5 17.7 4e-13 49.5 17.7 6.0 5 1 1 6 6 6 1 von Willebrand factor type C domain EGF_3 PF12947.7 KFP18417.1 - 2.5e-07 30.8 7.2 2.5e-07 30.8 7.2 5.9 6 0 0 6 6 6 2 EGF domain EGF_CA PF07645.15 KFP18417.1 - 5.2e-06 26.6 1.9 5.2e-06 26.6 1.9 5.5 4 0 0 4 4 4 3 Calcium-binding EGF domain Laminin_G_3 PF13385.6 KFP18417.1 - 0.0026 17.9 1.1 0.33 11.1 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP18417.1 - 0.0031 17.8 8.3 0.0031 17.8 8.3 4.9 4 0 0 4 4 4 1 EGF-like domain cEGF PF12662.7 KFP18417.1 - 0.011 15.6 0.5 0.011 15.6 0.5 5.1 5 0 0 5 5 5 0 Complement Clr-like EGF-like ROS_MUCR PF05443.11 KFP18418.1 - 0.065 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein PrmA PF06325.13 KFP18420.1 - 5.3e-09 35.9 0.0 8.5e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFP18420.1 - 2.5e-08 34.5 0.0 5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP18420.1 - 8.9e-07 29.5 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP18420.1 - 0.00018 21.3 0.1 0.0004 20.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP18420.1 - 0.00028 20.7 0.0 0.00051 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFP18420.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KFP18420.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFP18420.1 - 0.0037 16.2 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KFP18420.1 - 0.0045 17.7 0.0 0.0078 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP18420.1 - 0.016 15.0 0.2 0.035 13.9 0.1 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KFP18420.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KFP18420.1 - 0.031 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFP18420.1 - 0.049 13.6 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 KFP18420.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PRMT5 PF05185.16 KFP18420.1 - 0.09 12.6 0.2 0.18 11.6 0.2 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KFP18420.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_1 PF00036.32 KFP18422.1 - 1.3e-08 33.8 2.1 0.0005 19.4 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP18422.1 - 4.7e-08 32.3 0.1 0.01 15.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFP18422.1 - 1.3e-06 28.7 0.0 1.3e-06 28.7 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP18422.1 - 4.4e-05 22.8 0.0 0.023 14.2 0.0 3.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP18422.1 - 0.00036 20.3 0.3 0.0035 17.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair LMP PF04778.12 KFP18422.1 - 0.0096 15.8 11.1 0.0096 15.8 11.1 2.0 1 1 1 2 2 2 1 LMP repeated region FTCD_C PF04961.12 KFP18422.1 - 0.017 14.9 4.2 0.049 13.4 4.2 1.8 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase ZnuA PF01297.17 KFP18422.1 - 0.31 10.4 5.4 0.25 10.7 4.4 1.3 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF4407 PF14362.6 KFP18422.1 - 1.3 8.3 18.7 3.3 7.0 18.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EPOP PF15223.6 KFP18422.1 - 2 7.7 11.3 1.2 8.4 9.6 1.4 1 1 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein V_ATPase_I PF01496.19 KFP18422.1 - 4.8 5.0 19.4 6.4 4.6 19.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNase_J_C PF17770.1 KFP18422.1 - 7.8 7.6 7.1 0.82 10.8 1.1 2.6 3 1 1 4 4 3 0 Ribonuclease J C-terminal domain Tetraspanin PF00335.20 KFP18424.1 - 6.5e-49 166.7 13.4 7.1e-49 166.6 13.4 1.0 1 0 0 1 1 1 1 Tetraspanin family OppC_N PF12911.7 KFP18424.1 - 0.037 14.0 2.2 1.3 9.0 1.2 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C TadF PF16964.5 KFP18424.1 - 0.065 13.0 0.2 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative tight adherence pilin protein F DUF2207 PF09972.9 KFP18424.1 - 0.065 12.0 5.6 0.14 10.9 3.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 KFP18424.1 - 0.31 12.0 2.2 7.9 7.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 KFP18424.1 - 0.32 10.6 3.2 0.25 11.0 0.8 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Phage_holin_3_6 PF07332.11 KFP18424.1 - 2.3 8.3 6.7 0.72 9.9 3.3 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Sigma_reg_N PF13800.6 KFP18424.1 - 4.4 7.7 6.0 0.67 10.3 1.4 2.0 2 1 0 2 2 2 0 Sigma factor regulator N-terminal YBD PF17725.1 KFP18426.1 - 9.7e-96 319.6 1.5 1.2e-95 319.2 1.5 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KFP18426.1 - 2e-27 95.0 0.0 4.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain MSP1a PF11670.8 KFP18426.1 - 0.29 10.4 1.0 0.47 9.7 1.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Tub PF01167.18 KFP18427.1 - 3.8e-94 315.0 0.0 5.2e-94 314.5 0.0 1.2 1 0 0 1 1 1 1 Tub family Tub_N PF16322.5 KFP18427.1 - 3.6e-54 184.3 10.3 5e-54 183.9 10.3 1.2 1 0 0 1 1 1 1 Tubby N-terminal DUF3527 PF12043.8 KFP18427.1 - 0.078 12.5 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) RHINO PF15319.6 KFP18428.1 - 4.4e-82 275.8 6.7 4.9e-82 275.7 6.7 1.0 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Forkhead PF00250.18 KFP18429.1 - 1.9e-31 108.1 1.2 1.1e-30 105.8 0.4 2.2 1 1 1 2 2 2 1 Forkhead domain Asp_protease PF09668.10 KFP18430.1 - 6.2e-09 35.7 0.0 9.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFP18430.1 - 0.0044 17.5 0.0 0.0096 16.5 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Itfg2 PF15907.5 KFP18431.1 - 5e-165 548.5 0.1 5.9e-165 548.2 0.1 1.0 1 0 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 KFP18431.1 - 1.6e-11 44.2 0.3 0.0022 18.0 0.0 3.5 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 KFP18431.1 - 4.8e-05 23.9 1.3 0.25 12.0 0.1 3.8 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 KFP18431.1 - 0.046 12.5 0.0 8.5 5.0 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal PHTB1_N PF14727.6 KFP18431.1 - 0.11 11.8 0.0 3.5 6.9 0.0 2.7 3 1 1 4 4 4 0 PTHB1 N-terminus FG-GAP PF01839.23 KFP18431.1 - 0.17 12.0 0.6 1.3 9.3 0.1 2.6 3 0 0 3 3 3 0 FG-GAP repeat FKBP_C PF00254.28 KFP18432.1 - 1.6e-47 159.7 0.0 3.2e-30 104.3 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KFP18432.1 - 2.4e-18 65.1 10.4 3.4e-09 36.1 2.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP18432.1 - 2.6e-14 52.1 13.4 3.7e-06 26.6 1.3 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP18432.1 - 6.3e-08 32.8 4.9 0.0046 17.5 0.0 4.3 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP18432.1 - 4.1e-07 29.7 10.9 0.00036 20.5 0.9 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP18432.1 - 4.8e-07 30.0 2.8 2.5e-05 24.5 1.3 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP18432.1 - 2.2e-06 27.2 6.8 0.0005 19.7 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KFP18432.1 - 2.2e-05 24.9 5.0 0.013 16.0 3.7 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFP18432.1 - 0.00016 20.5 0.9 0.00023 20.0 0.9 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_16 PF13432.6 KFP18432.1 - 0.00035 21.2 4.0 0.31 11.7 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP18432.1 - 0.00039 20.2 4.2 0.074 13.1 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP18432.1 - 0.00088 19.4 0.0 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP18432.1 - 0.0011 19.6 0.5 0.28 12.1 0.0 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP18432.1 - 0.0011 19.0 0.3 0.0011 19.0 0.3 3.2 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KFP18432.1 - 0.013 15.5 0.4 0.013 15.5 0.4 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 KFP18432.1 - 0.027 14.8 5.8 0.41 11.1 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP18432.1 - 0.15 12.3 8.9 1.9 8.8 5.6 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 KFP18432.1 - 0.8 10.1 6.2 4.7 7.7 0.4 2.9 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Peptidase_M60 PF13402.6 KFP18433.1 - 8.7e-76 255.0 0.8 1.2e-75 254.6 0.8 1.2 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 KFP18433.1 - 8.9e-26 89.9 0.0 2.3e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases LBP_M PF17385.2 KFP18433.1 - 0.00065 19.3 0.0 0.16 11.5 0.0 3.1 3 0 0 3 3 3 2 Lacto-N-biose phosphorylase central domain Macro PF01661.21 KFP18434.1 - 2.4e-28 98.6 0.0 4.3e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Macro domain Histone_H2A_C PF16211.5 KFP18434.1 - 6.8e-18 64.1 1.5 6.8e-18 64.1 1.5 2.6 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 KFP18434.1 - 1.4e-15 57.8 1.9 3e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP18434.1 - 0.0048 17.2 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1764 PF08576.10 KFP18434.1 - 0.014 16.3 1.7 0.033 15.1 1.7 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Clp_N PF02861.20 KFP18434.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component YihI PF04220.12 KFP18434.1 - 0.12 12.1 5.5 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) IL8 PF00048.20 KFP18435.1 - 0.0019 18.3 2.1 0.0026 17.9 2.1 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like PROL5-SMR PF15621.6 KFP18435.1 - 0.065 13.8 1.0 0.1 13.1 0.9 1.5 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Mito_carr PF00153.27 KFP18436.1 - 2.6e-51 171.5 2.1 1.2e-21 76.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF787 PF05619.11 KFP18436.1 - 0.029 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) DUF2475 PF10629.9 KFP18436.1 - 0.22 11.8 0.6 0.83 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) IL13 PF03487.13 KFP18437.1 - 0.075 12.8 3.4 0.35 10.7 3.4 2.1 1 1 0 1 1 1 0 Interleukin-13 F-box-like PF12937.7 KFP18438.1 - 4.4e-12 45.7 1.8 1e-11 44.5 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFP18438.1 - 1.7e-10 40.5 1.3 1.7e-10 40.5 1.3 2.3 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 KFP18438.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box Fasciclin PF02469.22 KFP18439.1 - 4.6e-105 346.9 3.2 1.7e-33 115.5 0.2 4.3 4 0 0 4 4 4 4 Fasciclin domain DUF5618 PF18498.1 KFP18439.1 - 0.053 13.7 0.1 20 5.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5618) Fibrillin_U_N PF18193.1 KFP18439.1 - 0.37 11.0 1.8 1 9.5 1.8 1.7 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain MH2 PF03166.14 KFP18440.1 - 6e-76 254.8 1.4 8.4e-76 254.3 1.4 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP18440.1 - 2.6e-42 143.2 0.3 5.9e-42 142.1 0.3 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP18440.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFP18440.1 - 0.13 12.2 0.8 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) SPARC_Ca_bdg PF10591.9 KFP18441.1 - 1.8e-32 112.0 0.4 3.8e-32 111.0 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.18 KFP18441.1 - 1.6e-18 66.1 5.0 1.6e-18 66.1 5.0 2.5 2 1 0 2 2 2 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.15 KFP18441.1 - 2.5e-10 40.3 11.4 3.7e-10 39.8 7.5 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP18441.1 - 0.0009 19.2 5.3 0.0009 19.2 5.3 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP18441.1 - 0.063 13.7 0.0 1.1 9.7 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain pair GON PF08685.11 KFP18443.1 - 0.22 11.4 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 GON domain AAA_6 PF12774.7 KFP18444.1 - 7.8e-132 439.2 0.4 3.7e-130 433.7 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFP18444.1 - 3.9e-109 365.4 4.1 3.9e-109 365.4 4.1 5.6 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFP18444.1 - 4.9e-75 251.4 2.8 4.9e-75 251.4 2.8 5.0 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFP18444.1 - 1e-55 188.9 0.3 4.1e-52 177.1 0.1 4.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KFP18444.1 - 4.5e-44 150.9 0.6 4.5e-44 150.9 0.6 3.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KFP18444.1 - 1.8e-38 132.0 0.0 5.8e-38 130.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KFP18444.1 - 3.6e-37 127.4 0.0 1.9e-23 83.0 0.0 5.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KFP18444.1 - 1.6e-36 125.0 0.1 4.2e-34 117.2 0.1 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain DHC_N1 PF08385.12 KFP18444.1 - 9.3e-36 123.6 5.4 9.3e-36 123.6 5.4 4.2 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 KFP18444.1 - 2.1e-28 99.1 0.6 7.6e-25 87.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KFP18444.1 - 2.4e-26 92.6 11.9 8.4e-26 90.8 12.0 1.9 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 KFP18444.1 - 1.1e-08 35.4 4.8 0.019 15.2 0.0 5.4 4 1 0 5 5 3 2 AAA domain RsgA_GTPase PF03193.16 KFP18444.1 - 3.8e-07 30.2 0.5 0.00025 21.0 0.0 4.6 4 0 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 KFP18444.1 - 4.5e-07 30.4 22.5 0.00073 20.0 0.0 8.5 8 1 1 9 9 8 2 AAA ATPase domain AAA PF00004.29 KFP18444.1 - 3.5e-05 24.2 4.2 0.65 10.4 0.0 5.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFP18444.1 - 4.8e-05 23.2 1.2 0.033 13.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 KFP18444.1 - 8e-05 23.2 12.1 0.0029 18.1 0.0 5.4 6 0 0 6 6 4 2 ABC transporter AAA_18 PF13238.6 KFP18444.1 - 0.00066 20.2 0.2 1.7 9.2 0.0 4.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KFP18444.1 - 0.0012 18.5 0.0 0.29 10.9 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFP18444.1 - 0.0013 18.5 0.6 0.28 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFP18444.1 - 0.0026 18.1 0.3 1.1 9.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase Rad17 PF03215.15 KFP18444.1 - 0.0029 17.5 0.6 5.7 6.8 0.0 4.6 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_28 PF13521.6 KFP18444.1 - 0.012 15.9 0.3 0.4 10.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KFP18444.1 - 0.013 14.8 0.0 0.11 11.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 KFP18444.1 - 0.014 15.2 0.7 0.44 10.3 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFP18444.1 - 0.019 15.1 2.4 0.07 13.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KFP18444.1 - 0.038 13.9 0.9 12 5.8 0.2 4.1 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 KFP18444.1 - 0.071 13.6 0.0 0.071 13.6 0.0 9.4 10 1 0 10 10 9 0 AAA domain ATPase_2 PF01637.18 KFP18444.1 - 0.12 12.3 0.0 0.12 12.3 0.0 5.1 6 0 0 6 6 4 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KFP18444.1 - 0.18 11.8 0.7 1 9.4 0.0 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2968 PF11180.8 KFP18444.1 - 0.79 9.3 23.6 0.49 10.0 7.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ERM PF00769.19 KFP18444.1 - 0.98 9.2 49.9 0.024 14.5 10.6 4.1 4 0 0 4 4 4 0 Ezrin/radixin/moesin family Guanylate_kin PF00625.21 KFP18444.1 - 1.4 8.5 4.8 17 5.1 0.0 3.7 3 0 0 3 3 3 0 Guanylate kinase Cullin_binding PF03556.15 KFP18445.1 - 2.5e-30 105.4 4.5 3.6e-30 104.9 4.5 1.2 1 0 0 1 1 1 1 Cullin binding Peptidase_M10 PF00413.24 KFP18446.1 - 6.8e-62 208.0 0.0 1.3e-61 207.1 0.0 1.5 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP18446.1 - 6.2e-43 144.5 11.1 1.2e-13 50.8 0.1 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP18446.1 - 8.1e-13 48.4 0.1 1.5e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP18446.1 - 0.0052 16.4 0.5 2.8 7.5 0.3 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP18446.1 - 0.01 16.4 0.3 0.024 15.2 0.3 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP18446.1 - 0.079 13.1 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KFP18446.1 - 0.12 11.6 1.6 0.13 11.4 0.4 1.7 2 0 0 2 2 2 0 Met-zincin Peptidase_M57 PF12388.8 KFP18446.1 - 0.24 11.0 0.3 0.48 10.0 0.3 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 KFP18447.1 - 1.1e-62 210.6 0.1 3.5e-62 208.9 0.0 1.8 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.19 KFP18447.1 - 2.3e-37 126.7 7.6 8.6e-12 44.8 0.5 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP18447.1 - 2.7e-11 43.5 0.2 8.7e-11 41.9 0.1 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP18447.1 - 0.00046 19.9 0.3 0.85 9.2 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 KFP18447.1 - 0.0012 19.4 0.1 0.0048 17.4 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP18447.1 - 0.0037 17.5 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFP18447.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KFP18447.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 KFP18447.1 - 0.067 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 KFP18447.1 - 0.099 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KFP18449.1 - 3e-65 218.9 0.0 3.9e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.18 KFP18449.1 - 2.8e-10 40.2 0.1 6.4e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.24 KFP18449.1 - 0.00054 19.6 0.1 0.19 11.3 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFP18449.1 - 0.0073 15.5 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 KFP18449.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFP18449.1 - 0.027 15.0 0.4 0.054 14.0 0.4 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP18449.1 - 0.083 13.0 0.6 0.15 12.2 0.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KFP18449.1 - 0.16 10.9 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 MGC-24 PF05283.11 KFP18450.1 - 5.8e-09 36.5 10.0 8.5e-09 36.0 10.0 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KFP18450.1 - 0.66 8.0 9.9 0.65 8.1 9.9 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BIR PF00653.21 KFP18451.1 - 3.9e-66 219.7 13.3 7.8e-22 77.7 0.1 3.8 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain CARD PF00619.21 KFP18451.1 - 2e-22 79.0 0.7 3.4e-22 78.3 0.1 1.8 2 0 0 2 2 2 1 Caspase recruitment domain zf-C3HC4_3 PF13920.6 KFP18451.1 - 1.3e-14 53.8 8.2 1.3e-14 53.8 8.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP18451.1 - 9.4e-08 31.8 7.9 2.8e-07 30.3 7.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 KFP18451.1 - 3.4e-07 30.4 0.5 0.49 10.4 0.0 3.7 3 0 0 3 3 3 3 C3HC zinc finger-like zf-RING_5 PF14634.6 KFP18451.1 - 0.0056 16.6 7.1 0.0056 16.6 7.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF2039 PF10217.9 KFP18451.1 - 0.12 12.7 4.4 0.34 11.3 4.4 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_N PF01194.17 KFP18451.1 - 0.21 11.9 7.9 3 8.2 0.0 3.3 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit zf-RING_UBOX PF13445.6 KFP18451.1 - 0.29 11.2 6.2 0.69 10.0 3.5 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP18451.1 - 0.41 10.5 13.4 0.21 11.4 9.9 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4498 PF14926.6 KFP18452.1 - 2.2e-104 348.1 2.3 2.5e-104 348.0 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Fibrinogen_C PF00147.18 KFP18453.1 - 3e-57 193.9 2.9 4.3e-57 193.5 2.9 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain C1_1 PF00130.22 KFP18456.1 - 0.0012 18.7 4.4 0.0017 18.2 4.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KFP18456.1 - 0.037 14.4 4.7 0.058 13.7 4.7 1.4 1 0 0 1 1 1 0 RING-like domain SUZ PF12752.7 KFP18457.1 - 3.3e-12 47.0 3.2 3.3e-12 47.0 3.2 4.4 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 KFP18457.1 - 9.2e-11 41.6 0.1 2.8e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 R3H domain Ank PF00023.30 KFP18458.1 - 1.1e-29 101.5 2.3 4.6e-06 26.8 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 KFP18458.1 - 3.3e-27 94.9 1.2 2.2e-12 47.4 0.0 2.8 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP18458.1 - 6.9e-27 93.5 4.0 8.2e-08 32.7 0.2 5.1 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18458.1 - 2.9e-22 76.3 5.8 0.00032 20.9 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFP18458.1 - 1.6e-21 76.0 4.4 6e-09 36.0 0.5 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP18458.1 - 7.2e-09 35.9 0.6 1.4e-08 34.9 0.6 1.5 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 KFP18459.1 - 8.5e-36 122.4 0.5 3.4e-17 62.8 0.5 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP18459.1 - 5e-26 90.0 0.3 4e-06 27.0 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFP18459.1 - 1.9e-25 88.9 1.5 4.3e-08 33.5 0.1 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP18459.1 - 4.4e-20 71.5 2.1 1.3e-09 38.1 0.6 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18459.1 - 1.5e-18 64.9 2.4 0.00028 21.1 0.0 4.9 6 0 0 6 6 6 3 Ankyrin repeat SOCS_box PF07525.16 KFP18459.1 - 6.2e-09 36.1 0.6 1.2e-08 35.1 0.6 1.5 1 0 0 1 1 1 1 SOCS box Peptidase_C48 PF02902.19 KFP18460.1 - 7.5e-49 166.5 1.3 1.4e-48 165.6 1.3 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KFP18460.1 - 0.015 14.1 2.2 1.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Vaccinia virus I7 processing peptidase ATP-synt_ab PF00006.25 KFP18461.1 - 5.4e-09 36.0 0.1 7.5e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 KFP18461.1 - 0.0022 17.8 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 2 T3SS EscN ATPase C-terminal domain ATP-synt_ab PF00006.25 KFP18462.1 - 8.9e-27 94.1 0.1 1.3e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFP18462.1 - 1.5e-06 28.6 0.4 3.5e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KFP18462.1 - 0.0064 15.7 0.1 0.0077 15.4 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 KFP18462.1 - 0.007 16.3 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 KFP18462.1 - 0.0076 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 KFP18462.1 - 0.029 14.3 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KFP18462.1 - 0.034 13.9 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFP18462.1 - 0.047 14.0 0.3 0.08 13.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP18462.1 - 0.051 14.1 0.1 0.079 13.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KFP18462.1 - 0.088 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFP18462.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFP18462.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFP18462.1 - 0.16 12.4 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KFP18462.1 - 0.2 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 KFP18462.1 - 0.2 10.5 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CS PF04969.16 KFP18463.1 - 5.5e-08 33.7 0.2 7.7e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.24 KFP18463.1 - 0.2 12.4 6.5 0.59 10.9 6.5 1.9 2 0 0 2 2 2 0 Protein kinase C terminal domain NAC PF01849.18 KFP18464.1 - 2.4e-25 88.3 1.0 9.9e-25 86.3 0.2 2.2 2 0 0 2 2 2 1 NAC domain RNA_pol_Rpo13 PF12136.8 KFP18464.1 - 0.043 13.7 3.9 0.097 12.6 3.9 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain BTB PF00651.31 KFP18465.1 - 1.6e-23 83.1 0.1 3.1e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP18465.1 - 3.1e-14 52.7 50.6 2.9e-07 30.6 5.2 9.9 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2 PF00096.26 KFP18465.1 - 1.5e-06 28.3 78.6 0.0027 18.1 3.6 9.8 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18465.1 - 2.2e-06 28.0 75.6 0.19 12.6 2.9 10.4 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP18465.1 - 2.9e-05 24.8 3.3 2.9e-05 24.8 3.3 4.0 2 2 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 KFP18465.1 - 0.12 12.7 5.3 8.4 6.8 0.1 3.8 3 1 1 4 4 4 0 BolA-like protein zf_C2H2_13 PF18508.1 KFP18465.1 - 0.32 10.6 2.1 3.9 7.1 0.1 3.5 3 0 0 3 3 3 0 Zinc finger domain zinc_ribbon_15 PF17032.5 KFP18465.1 - 0.5 11.1 23.5 8.7 7.2 0.7 5.6 1 1 4 6 6 6 0 zinc-ribbon family Elf1 PF05129.13 KFP18465.1 - 7.6 6.7 32.6 0.21 11.7 1.3 5.8 3 3 2 5 5 5 0 Transcription elongation factor Elf1 like RVT_1 PF00078.27 KFP18466.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 KFP18467.1 - 2.3e-25 88.8 4.5 2.7e-16 59.7 0.7 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP18467.1 - 5.6e-25 85.0 12.9 9.6e-08 31.1 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KFP18467.1 - 9.9e-23 78.1 5.5 2.9e-07 29.9 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KFP18467.1 - 2.3e-17 61.6 9.4 6.1e-06 25.5 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFP18467.1 - 2.8e-13 49.5 11.5 3e-05 23.8 0.4 4.3 4 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP18467.1 - 1.5e-05 25.3 2.0 0.061 13.6 0.5 3.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP18467.1 - 0.00025 21.2 0.1 0.069 13.4 0.0 2.8 3 0 0 3 3 3 1 Dockerin type I domain p25-alpha PF05517.12 KFP18467.1 - 0.0014 18.8 1.2 0.051 13.7 0.4 2.4 2 0 0 2 2 2 1 p25-alpha Caleosin PF05042.13 KFP18467.1 - 0.0023 17.9 6.2 0.1 12.5 3.3 3.3 2 1 0 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.6 KFP18467.1 - 0.0034 17.7 0.1 5.6 7.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain IL3 PF02059.15 KFP18467.1 - 0.0041 17.2 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Interleukin-3 EF-hand_4 PF12763.7 KFP18467.1 - 0.034 14.1 7.1 9.8 6.2 0.0 3.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand XPG_I PF00867.18 KFP18468.1 - 1.2e-25 89.7 0.1 1.2e-25 89.7 0.1 2.3 3 0 0 3 3 3 1 XPG I-region Chromo_2 PF18704.1 KFP18468.1 - 1.4e-21 76.5 0.5 4.5e-21 74.9 0.5 2.0 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 A2L_zn_ribbon PF08792.10 KFP18468.1 - 0.0064 16.2 1.7 0.0064 16.2 1.7 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain RecR PF02132.15 KFP18468.1 - 0.19 11.3 1.6 0.69 9.5 1.6 2.0 1 0 0 1 1 1 0 RecR protein HLH PF00010.26 KFP18469.1 - 1.3e-11 44.3 2.1 1.7e-11 43.9 1.4 1.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Zona_pellucida PF00100.23 KFP18470.1 - 1.4e-41 143.1 3.3 1.1e-38 133.5 0.2 2.9 2 1 1 3 3 3 2 Zona pellucida-like domain Ion_trans PF00520.31 KFP18471.1 - 1.7e-48 165.0 0.8 2.3e-48 164.6 0.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP18471.1 - 1.8e-32 111.6 0.2 7.1e-32 109.6 0.2 2.1 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP18471.1 - 5.7e-12 45.4 3.8 5.7e-12 45.4 3.8 1.9 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KFP18471.1 - 0.0094 16.0 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain adh_short PF00106.25 KFP18473.1 - 3e-18 66.0 0.0 3.1e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP18473.1 - 1.7e-12 47.4 0.0 8.1e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 5-nucleotidase PF06189.12 KFP18474.1 - 2.2e-106 354.7 0.0 2.7e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase Clathrin PF00637.20 KFP18475.1 - 1.2e-194 637.9 46.4 1e-34 119.4 2.7 8.9 8 1 1 9 9 9 8 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFP18475.1 - 1.5e-48 160.8 1.6 1.3e-09 37.9 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFP18475.1 - 2e-30 104.5 1.9 9e-30 102.4 0.3 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 KFP18475.1 - 4.7e-11 41.8 0.4 1.5e-10 40.3 0.4 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KFP18475.1 - 9.6e-05 21.6 4.3 0.0013 17.9 0.1 3.9 3 1 0 4 4 4 1 Coatomer WD associated region TPR_19 PF14559.6 KFP18475.1 - 0.024 15.1 6.2 37 4.9 0.2 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP18475.1 - 0.043 13.9 13.0 1.2 9.3 0.3 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF745 PF05335.13 KFP18476.1 - 0.00088 19.0 1.0 0.013 15.2 0.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF745) KxDL PF10241.9 KFP18476.1 - 0.001 19.3 5.4 0.12 12.6 0.1 3.2 2 1 1 3 3 3 1 Uncharacterized conserved protein DUF1664 PF07889.12 KFP18476.1 - 0.0018 18.3 3.1 0.063 13.3 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KFP18476.1 - 0.0067 16.7 8.9 0.016 15.5 3.8 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) PspA_IM30 PF04012.12 KFP18476.1 - 0.011 15.3 0.3 0.011 15.3 0.3 2.0 3 0 0 3 3 2 0 PspA/IM30 family DUF677 PF05055.12 KFP18476.1 - 0.024 13.5 5.3 0.88 8.4 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF677) Fib_alpha PF08702.10 KFP18476.1 - 0.025 14.8 6.7 2.9 8.1 0.2 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family V-SNARE_C PF12352.8 KFP18476.1 - 0.025 14.9 6.2 0.15 12.4 0.5 3.1 3 1 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.11 KFP18476.1 - 0.051 13.8 0.8 0.84 9.9 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.10 KFP18476.1 - 0.091 12.5 2.5 0.41 10.4 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF5446 PF17522.2 KFP18476.1 - 0.11 12.7 1.2 6.7 7.0 0.6 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5446) APC_N_CC PF16689.5 KFP18476.1 - 0.14 12.3 2.7 1.8 8.7 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain BLOC1_2 PF10046.9 KFP18476.1 - 0.16 12.3 9.1 2.1 8.7 2.5 3.2 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.12 KFP18476.1 - 0.2 12.0 5.2 1.4 9.3 1.6 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3552 PF12072.8 KFP18476.1 - 0.22 10.9 7.0 6.1 6.2 1.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) CREPT PF16566.5 KFP18476.1 - 0.23 11.7 6.1 0.29 11.3 1.6 2.5 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2203 PF09969.9 KFP18476.1 - 0.27 11.9 2.7 2.9 8.6 2.7 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SlyX PF04102.12 KFP18476.1 - 0.29 11.8 4.4 4.3 8.0 0.5 3.0 3 1 1 4 4 3 0 SlyX SNARE PF05739.19 KFP18476.1 - 0.31 11.1 6.2 2.6 8.1 0.2 3.5 4 0 0 4 4 4 0 SNARE domain BORCS7 PF16088.5 KFP18476.1 - 0.32 11.3 3.9 12 6.2 0.0 3.4 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF16 PF01519.16 KFP18476.1 - 0.42 11.1 7.1 4.8 7.7 4.1 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 XhlA PF10779.9 KFP18476.1 - 0.66 10.2 11.1 3.7 7.8 0.1 3.5 3 1 2 5 5 5 0 Haemolysin XhlA BRE1 PF08647.11 KFP18476.1 - 0.84 9.7 10.8 2.6 8.2 0.4 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 KFP18476.1 - 1.1 9.8 5.3 35 4.9 2.5 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5089 PF17002.5 KFP18476.1 - 1.9 8.3 10.8 51 3.6 10.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) Uds1 PF15456.6 KFP18476.1 - 2 8.6 10.6 14 5.8 5.2 2.9 2 1 0 2 2 2 0 Up-regulated During Septation UPF0242 PF06785.11 KFP18476.1 - 2.7 8.1 10.3 11 6.1 10.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KFP18476.1 - 2.7 8.1 11.3 0.076 13.1 2.4 2.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KFP18476.1 - 3 7.6 6.5 0.81 9.5 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Holin_BhlA PF10960.8 KFP18476.1 - 3.6 7.6 6.8 0.99 9.4 0.3 2.8 3 0 0 3 3 3 0 BhlA holin family Syntaxin_2 PF14523.6 KFP18476.1 - 9.2 6.7 11.8 1.1 9.7 2.1 2.7 2 1 1 3 3 3 0 Syntaxin-like protein PI3_PI4_kinase PF00454.27 KFP18477.1 - 2.6e-41 142.1 0.4 3.2e-28 99.2 0.4 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFP18477.1 - 8.7e-35 119.8 0.0 2.2e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ribosomal_L18_c PF14204.6 KFP18477.1 - 0.14 13.1 0.2 0.34 11.9 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Serpin PF00079.20 KFP18478.1 - 3.4e-110 368.9 2.3 4.6e-110 368.4 2.3 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1139 PF06599.11 KFP18478.1 - 0.035 13.5 1.4 0.058 12.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) BTB PF00651.31 KFP18480.1 - 9.8e-27 93.4 0.2 1.5e-26 92.8 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP18480.1 - 1.5e-26 91.3 24.4 7.4e-06 26.1 1.3 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18480.1 - 2.4e-23 80.8 22.7 0.00032 21.3 0.5 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP18480.1 - 2.6e-19 68.7 30.8 5.8e-08 32.8 0.2 7.4 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP18480.1 - 7e-16 58.1 3.4 0.00027 21.1 0.3 5.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP18480.1 - 2.2e-11 43.7 13.3 0.0035 17.7 0.4 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP18480.1 - 3.3e-10 39.7 21.5 0.018 15.0 0.3 6.0 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP18480.1 - 1e-05 26.2 5.6 0.0028 18.3 0.3 4.2 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KFP18480.1 - 8.6e-05 22.2 16.6 0.23 11.2 0.4 4.7 5 0 0 5 5 4 3 zinc-finger C2H2-type zf-Di19 PF05605.12 KFP18480.1 - 0.00028 21.1 11.3 0.05 13.9 0.6 3.7 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KFP18480.1 - 0.0012 19.1 10.2 9.6 6.6 1.3 4.5 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 KFP18480.1 - 0.0017 17.9 4.4 2 8.1 0.0 3.7 3 0 0 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KFP18480.1 - 0.0023 18.4 15.9 0.18 12.3 0.4 5.4 1 1 4 5 5 5 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFP18480.1 - 0.0023 18.2 14.5 7.8 6.9 0.3 5.1 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 KFP18480.1 - 0.0067 16.7 6.0 2.5 8.5 0.1 3.7 2 1 1 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-AN1 PF01428.16 KFP18480.1 - 0.046 13.9 10.1 27 5.0 0.1 4.6 4 0 0 4 4 4 0 AN1-like Zinc finger zf-MYST PF17772.1 KFP18480.1 - 0.072 12.7 0.2 12 5.6 0.0 3.5 3 0 0 3 3 3 0 MYST family zinc finger domain GAGA PF09237.11 KFP18480.1 - 0.14 12.0 4.1 1.6 8.6 0.2 3.1 2 1 1 3 3 3 0 GAGA factor zf-H2C2_5 PF13909.6 KFP18480.1 - 0.27 11.0 22.1 4.6 7.1 0.1 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain LIM PF00412.22 KFP18480.1 - 0.43 10.9 10.1 0.24 11.7 0.5 3.8 2 1 2 4 4 3 0 LIM domain zf_UBZ PF18439.1 KFP18480.1 - 0.43 10.2 14.3 3.2 7.4 0.1 5.2 6 0 0 6 6 5 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KFP18480.1 - 0.44 10.6 17.0 2 8.5 3.7 4.9 4 1 1 5 5 4 0 BED zinc finger zinc_ribbon_15 PF17032.5 KFP18480.1 - 0.86 10.4 8.8 4.7 8.0 0.6 3.7 1 1 0 2 2 2 0 zinc-ribbon family FYVE PF01363.21 KFP18480.1 - 0.93 9.7 9.1 2e+02 2.2 9.1 3.0 1 1 0 1 1 1 0 FYVE zinc finger zf-HYPF PF07503.12 KFP18480.1 - 2.9 7.8 7.0 17 5.3 0.4 3.4 3 1 0 3 3 3 0 HypF finger zf-RING_5 PF14634.6 KFP18480.1 - 6.4 6.8 8.4 1.1e+02 2.9 0.1 3.7 2 1 0 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.10 KFP18480.1 - 7.9 6.7 14.4 3.6 7.8 4.3 4.1 2 1 3 5 5 5 0 Zinc ribbon domain zf-LYAR PF08790.11 KFP18480.1 - 8.5 6.4 11.6 2.2 8.3 0.1 4.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger UQ_con PF00179.26 KFP18481.1 - 5.3e-44 149.3 0.4 6e-44 149.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP18481.1 - 3.7e-05 24.0 0.1 5.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KFP18481.1 - 3.9e-05 23.4 0.0 4.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFP18481.1 - 4.2e-05 23.4 0.1 7.4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 UEV domain YdjC PF04794.12 KFP18482.1 - 6.2e-34 118.0 0.0 7.3e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein MIR PF02815.19 KFP18483.1 - 4.3e-12 46.2 0.0 5.2e-09 36.2 0.0 2.0 1 1 1 2 2 2 2 MIR domain Topoisom_bac PF01131.20 KFP18484.1 - 6.9e-119 397.5 0.0 8.3e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KFP18484.1 - 5.3e-14 52.3 0.0 1.2e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF2204 PF09970.9 KFP18484.1 - 0.14 11.8 0.1 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) RVT_1 PF00078.27 KFP18490.1 - 0.0021 17.6 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TLV_coat PF00429.19 KFP18494.1 - 0.00056 18.7 0.5 0.00057 18.7 0.5 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) RVT_1 PF00078.27 KFP18497.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 KFP18502.1 - 8.6e-24 83.1 11.6 7.3e-13 48.1 0.3 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP18502.1 - 5.2e-10 39.4 11.2 0.00034 20.9 0.4 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP18502.1 - 1.2e-08 35.0 0.4 2.6e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP18502.1 - 0.00077 19.0 3.3 0.017 14.6 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP18502.1 - 0.001 19.3 5.8 25 5.9 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP18502.1 - 0.074 13.1 7.9 5.7 7.3 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat PAC3 PF10178.9 KFP18503.1 - 1.6e-28 98.7 0.0 2.1e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Solute_trans_a PF03619.16 KFP18504.1 - 3.4e-93 312.0 22.3 4.1e-93 311.7 22.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha bZIP_Maf PF03131.17 KFP18505.1 - 1.6e-34 118.3 12.5 1.9e-34 118.0 12.5 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 KFP18505.1 - 0.00011 21.9 5.0 0.00011 21.9 5.0 2.1 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 KFP18505.1 - 0.0002 21.4 16.6 0.0046 17.0 16.6 2.4 1 1 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 KFP18505.1 - 0.003 17.7 7.8 0.0074 16.4 7.7 1.8 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF1192 PF06698.11 KFP18505.1 - 0.0054 16.8 6.2 0.043 13.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Prominin PF05478.11 KFP18505.1 - 0.013 13.5 1.2 0.016 13.2 1.2 1.0 1 0 0 1 1 1 0 Prominin Spc24 PF08286.11 KFP18505.1 - 0.033 14.4 1.4 0.06 13.6 0.2 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KFP18505.1 - 0.035 14.2 11.5 0.035 14.2 11.5 2.5 1 1 2 3 3 3 0 Basic region leucine zipper FapA PF03961.13 KFP18505.1 - 0.087 11.4 2.5 0.092 11.3 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Spc19 PF08287.11 KFP18505.1 - 0.25 11.2 10.1 0.35 10.7 10.1 1.2 1 0 0 1 1 1 0 Spc19 DUF4164 PF13747.6 KFP18505.1 - 0.28 11.5 8.3 0.66 10.3 8.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) GIT_CC PF16559.5 KFP18505.1 - 0.3 11.0 4.6 0.16 11.8 1.7 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mst1_SARAH PF11629.8 KFP18505.1 - 0.34 11.0 6.3 7.6 6.7 2.0 2.6 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 YabA PF06156.13 KFP18505.1 - 0.36 11.5 6.9 0.16 12.7 2.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 KFP18505.1 - 1.1 9.3 8.6 1.9 8.6 8.6 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 KFP18505.1 - 1.4 7.7 9.5 2.3 7.0 9.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KFP18505.1 - 2.2 8.8 13.5 4.2 7.9 7.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF2205 PF10224.9 KFP18505.1 - 2.8 8.0 8.2 0.83 9.7 3.1 2.2 1 1 1 2 2 2 0 Short coiled-coil protein XkdW PF09636.10 KFP18505.1 - 8.5 6.5 6.4 6.2 7.0 2.4 2.1 1 1 1 2 2 2 0 XkdW protein APG6_N PF17675.1 KFP18505.1 - 8.9 6.8 12.9 27 5.3 12.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Glyco_hydro_31 PF01055.26 KFP18506.1 - 8.3e-135 450.4 0.2 3.2e-67 227.7 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFP18506.1 - 1.6e-11 44.4 0.0 2.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFP18506.1 - 3.2e-10 40.2 0.1 1.5e-09 38.0 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KFP18506.1 - 0.19 12.0 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) DUF3677 PF12432.8 KFP18507.1 - 7.5e-32 109.5 3.9 7.5e-32 109.5 3.9 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) UNC45-central PF11701.8 KFP18507.1 - 0.0072 16.3 3.2 0.25 11.3 0.1 4.7 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central Cnd3 PF12719.7 KFP18507.1 - 0.042 13.0 8.5 1.4 8.1 0.0 4.0 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Homeodomain PF00046.29 KFP18508.1 - 8.1e-24 83.2 3.5 8.1e-24 83.2 3.5 1.6 2 0 0 2 2 2 1 Homeodomain PHM7_cyt PF14703.6 KFP18508.1 - 0.012 15.8 1.1 0.016 15.5 1.1 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter zf-AN1 PF01428.16 KFP18509.1 - 2.3e-19 69.2 25.5 3.4e-11 43.1 9.9 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger zf-C2H2_4 PF13894.6 KFP18509.1 - 0.022 15.6 7.3 8.1 7.6 0.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 KFP18509.1 - 0.048 13.9 23.8 0.66 10.2 14.5 3.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 KFP18509.1 - 0.051 13.5 7.9 1.6 8.7 0.7 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC PF07967.13 KFP18509.1 - 0.58 10.2 7.6 0.36 10.9 0.9 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like Transp_Tc5_C PF04236.15 KFP18509.1 - 0.64 10.4 15.5 2.2 8.7 5.5 2.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain FYVE PF01363.21 KFP18509.1 - 1.5 9.0 18.1 0.16 12.1 3.9 2.5 2 1 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 KFP18509.1 - 2.5 8.1 15.3 0.74 9.8 3.8 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-RRN7 PF11781.8 KFP18509.1 - 4.7 7.0 11.0 4.4 7.1 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 7tm_1 PF00001.21 KFP18510.1 - 2.3e-41 141.9 16.8 2.9e-41 141.5 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP18510.1 - 3.2e-05 23.4 16.1 4.2e-05 23.0 16.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Abhydrolase_9_N PF15420.6 KFP18510.1 - 0.64 10.0 3.1 1.1 9.2 3.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PHO4 PF01384.20 KFP18510.1 - 2.5 7.1 6.4 1 8.3 4.3 1.5 1 1 1 2 2 2 0 Phosphate transporter family DUF2157 PF09925.9 KFP18511.1 - 5.9 6.7 10.0 9.2 6.0 6.9 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) 7tm_1 PF00001.21 KFP18512.1 - 2.3e-13 50.1 16.8 3.3e-13 49.6 16.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Col_cuticle_N PF01484.17 KFP18512.1 - 0.56 10.3 4.6 1.1 9.4 0.1 3.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF2373 PF10180.9 KFP18513.1 - 5.3e-24 83.8 2.6 1.2e-23 82.7 2.6 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) RBM39linker PF15519.6 KFP18513.1 - 0.037 15.1 0.1 0.062 14.4 0.1 1.3 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Histone_HNS PF00816.21 KFP18513.1 - 0.11 13.3 7.4 0.069 14.0 5.6 1.7 2 0 0 2 2 2 0 H-NS histone family p450 PF00067.22 KFP18514.1 - 2e-126 422.5 1.0 2.2e-126 422.3 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP18515.1 - 4.7e-104 348.7 0.4 5.2e-104 348.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP18516.1 - 2.2e-121 405.8 0.3 2.5e-121 405.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArfGap PF01412.18 KFP18517.1 - 7e-28 97.1 0.1 1.2e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP18517.1 - 1.5e-22 80.1 0.1 1.5e-12 48.0 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFP18517.1 - 3.5e-08 33.8 0.9 4e-05 24.0 0.3 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFP18517.1 - 3e-05 24.2 3.9 0.078 13.3 0.1 3.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 KFP18517.1 - 0.0013 18.9 0.1 0.19 11.8 0.0 2.7 3 0 0 3 3 3 1 PH domain DUF410 PF04190.13 KFP18518.1 - 2.7e-66 224.0 0.1 1.6e-64 218.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF410) SDH_C PF18317.1 KFP18518.1 - 0.27 11.0 1.0 1.3 8.9 0.9 2.2 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain Sad1_UNC PF07738.13 KFP18519.1 - 3.7e-44 149.9 0.0 7.4e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MRP PF09387.10 KFP18519.1 - 2.3e-36 125.6 0.8 4.1e-36 124.8 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Sun2_CC2 PF18580.1 KFP18519.1 - 1.4e-10 41.3 2.4 4.3e-10 39.7 2.4 1.9 1 0 0 1 1 1 1 SUN2 coiled coil domain 2 SlyX PF04102.12 KFP18519.1 - 2.4 8.9 4.6 2.3 8.9 0.7 2.8 2 1 0 2 2 2 0 SlyX HEAT_2 PF13646.6 KFP18520.1 - 5e-12 46.0 0.1 0.00034 20.9 0.0 5.4 3 2 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP18520.1 - 4.9e-11 43.1 1.4 0.014 16.0 0.1 5.5 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFP18520.1 - 7.3e-08 32.0 18.4 0.58 10.6 0.1 9.1 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 KFP18520.1 - 3.1e-07 30.7 0.2 14 6.3 0.0 6.5 5 0 0 5 5 5 0 HEAT-like repeat CLASP_N PF12348.8 KFP18520.1 - 4.5e-07 29.7 4.9 0.0063 16.1 0.1 4.5 3 1 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 KFP18520.1 - 0.00027 20.2 11.0 0.00063 18.9 0.1 4.4 4 2 1 5 5 5 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 KFP18520.1 - 0.00042 20.0 5.4 0.25 10.8 0.6 5.2 3 1 1 4 4 4 1 Tti2 family STAR_dimer PF16544.5 KFP18520.1 - 0.0027 17.2 0.0 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 Homodimerisation region of STAR domain protein DUF2201_N PF13203.6 KFP18520.1 - 0.045 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Prok_Ub PF14454.6 KFP18520.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin DHHA2 PF02833.14 KFP18520.1 - 0.1 12.8 0.2 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 DHHA2 domain RTP1_C1 PF10363.9 KFP18520.1 - 0.33 11.2 4.9 9.9 6.4 0.0 4.1 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KFP18520.1 - 0.84 9.2 10.2 25 4.3 0.1 4.6 3 2 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II UME PF08064.13 KFP18520.1 - 3.3 7.7 11.6 7.1 6.6 1.6 4.4 4 1 1 5 5 5 0 UME (NUC010) domain cNMP_binding PF00027.29 KFP18521.1 - 1.6e-42 143.5 0.1 1.8e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KFP18521.1 - 7.5e-14 51.1 0.1 1.5e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 KFP18521.1 - 0.017 15.6 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF5586 PF17824.1 KFP18521.1 - 0.15 11.2 1.0 0.26 10.3 0.7 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5586) PDGF PF00341.17 KFP18522.1 - 1.1e-21 76.9 10.1 1.7e-21 76.3 10.1 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.13 KFP18522.1 - 7.3e-06 26.7 1.7 1e-05 26.2 0.1 1.9 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Forkhead PF00250.18 KFP18523.1 - 2.3e-37 127.1 0.2 2.8e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 Forkhead domain DUF3277 PF11681.8 KFP18523.1 - 0.057 13.3 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Fam20C PF06702.12 KFP18524.1 - 2e-106 354.7 0.2 2.8e-106 354.3 0.2 1.2 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 RVT_1 PF00078.27 KFP18526.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WSC PF01822.19 KFP18527.1 - 6.6e-31 106.3 18.0 1.9e-19 69.6 10.4 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.27 KFP18527.1 - 1.3e-07 31.4 0.2 2.5e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP18527.1 - 0.02 15.3 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family PAN_1 PF00024.26 KFP18527.1 - 5.1 7.1 8.0 25 4.9 0.2 3.2 3 0 0 3 3 3 0 PAN domain XAF1_C PF18608.1 KFP18528.1 - 3.2e-18 65.0 0.6 3.2e-18 65.0 0.6 4.2 4 1 1 5 5 5 1 XIAP-associated factor 1 C-terminal domain zf_UBZ PF18439.1 KFP18528.1 - 3.8e-06 26.4 26.6 0.022 14.4 0.1 6.4 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 KFP18528.1 - 0.13 12.1 14.6 1.3 8.9 0.1 3.6 1 1 2 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Na_sulph_symp PF00939.19 KFP18529.1 - 3.8e-120 402.1 22.2 4.5e-120 401.9 22.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP18529.1 - 7.9e-36 123.8 29.8 8.3e-22 77.7 1.9 3.1 2 1 1 3 3 3 3 Citrate transporter DUF4713 PF15831.5 KFP18529.1 - 5.7 7.5 13.2 30 5.2 0.2 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4713) Med31 PF05669.12 KFP18530.1 - 1e-40 137.6 11.2 1.6e-40 137.0 11.2 1.2 1 0 0 1 1 1 1 SOH1 DUF953 PF06110.11 KFP18531.1 - 6.7e-26 90.3 0.0 7.4e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DDHD PF02862.17 KFP18532.1 - 9.7e-52 176.3 0.0 3.2e-51 174.7 0.0 1.9 2 0 0 2 2 2 1 DDHD domain Acid_phosphat_B PF03767.14 KFP18532.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LNS2 PF08235.13 KFP18532.1 - 0.073 12.5 0.1 0.39 10.2 0.1 2.0 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) RCS1 PF07326.11 KFP18533.1 - 3.1e-25 89.5 0.2 3.3e-25 89.4 0.2 1.0 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 NanE PF04131.14 KFP18533.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase RCS1 PF07326.11 KFP18534.1 - 8.3e-57 192.8 8.9 9.1e-57 192.7 8.9 1.0 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 EPO_TPO PF00758.18 KFP18534.1 - 0.009 16.1 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin Tektin PF03148.14 KFP18535.1 - 2.6e-136 454.4 34.5 3.1e-136 454.1 34.5 1.1 1 0 0 1 1 1 1 Tektin family Las1 PF04031.13 KFP18535.1 - 0.39 10.8 3.1 14 5.8 0.2 2.2 2 0 0 2 2 2 0 Las1-like Exonuc_VII_L PF02601.15 KFP18535.1 - 4.7 6.7 21.3 1.3 8.5 9.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit CH PF00307.31 KFP18536.1 - 3.9e-21 75.3 0.0 6.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP18536.1 - 0.00025 20.8 0.1 0.00043 20.1 0.1 1.4 1 0 0 1 1 1 1 CAMSAP CH domain EGF PF00008.27 KFP18537.1 - 0.0017 18.6 3.2 0.0035 17.6 3.2 1.5 1 0 0 1 1 1 1 EGF-like domain LapA_dom PF06305.11 KFP18537.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Laminin_EGF PF00053.24 KFP18537.1 - 0.024 14.8 3.2 0.073 13.2 3.2 1.8 1 0 0 1 1 1 0 Laminin EGF domain DUF3340 PF11818.8 KFP18537.1 - 0.049 13.8 1.4 0.054 13.7 0.1 1.6 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF3021 PF11457.8 KFP18537.1 - 0.067 13.5 0.2 0.099 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Insulin_TMD PF17870.1 KFP18537.1 - 0.081 13.0 0.5 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 KFP18537.1 - 0.13 12.3 0.5 1.7 8.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) EGF_2 PF07974.13 KFP18537.1 - 0.18 12.2 6.4 0.38 11.1 6.4 1.6 1 0 0 1 1 1 0 EGF-like domain SH2 PF00017.24 KFP18540.1 - 5.3e-16 58.5 0.1 1.3e-15 57.2 0.1 1.7 1 0 0 1 1 1 1 SH2 domain PSCyt2 PF07583.11 KFP18540.1 - 0.34 10.8 7.5 0.1 12.5 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1549) Arm PF00514.23 KFP18541.1 - 2.3e-21 75.1 22.2 2.2e-07 30.7 0.3 8.6 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFP18541.1 - 2.8e-09 37.2 12.4 0.036 14.5 0.0 5.6 2 2 2 5 5 5 4 HEAT repeats V-ATPase_H_C PF11698.8 KFP18541.1 - 4.4e-06 26.8 11.9 7.7e-05 22.8 0.2 4.6 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_EZ PF13513.6 KFP18541.1 - 3.2e-05 24.3 7.5 0.3 11.7 0.0 5.8 4 2 2 6 6 6 1 HEAT-like repeat Proteasom_PSMB PF10508.9 KFP18541.1 - 5.7e-05 21.8 1.4 5.7e-05 21.8 1.4 3.0 2 2 1 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT PF02985.22 KFP18541.1 - 0.00036 20.5 3.3 9.8 6.7 0.1 6.0 7 0 0 7 7 7 1 HEAT repeat ThylakoidFormat PF11264.8 KFP18541.1 - 0.00071 19.3 6.1 0.12 12.0 1.7 2.6 2 0 0 2 2 2 2 Thylakoid formation protein V-ATPase_H_N PF03224.14 KFP18541.1 - 0.00079 18.8 16.5 0.2 10.9 1.0 4.9 2 2 2 4 4 4 1 V-ATPase subunit H Rcd1 PF04078.13 KFP18541.1 - 0.0032 16.8 6.7 0.31 10.3 0.4 4.2 3 1 1 4 4 4 1 Cell differentiation family, Rcd1-like RTTN_N PF14726.6 KFP18541.1 - 0.015 16.1 9.5 0.63 10.9 0.0 4.3 2 2 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning DUF2711 PF10924.8 KFP18541.1 - 0.028 14.0 0.1 0.077 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Vps39_1 PF10366.9 KFP18541.1 - 0.036 14.3 0.4 0.036 14.3 0.4 3.1 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Cnd1 PF12717.7 KFP18541.1 - 0.1 12.6 11.5 0.18 11.9 0.5 3.7 2 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Antirestrict PF03230.13 KFP18541.1 - 0.16 12.0 0.3 8.5 6.5 0.0 3.2 2 1 1 3 3 3 0 Antirestriction protein SapB_1 PF05184.15 KFP18541.1 - 0.25 11.4 1.5 1.4 9.0 0.5 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 DUF3361 PF11841.8 KFP18541.1 - 0.29 11.0 20.1 1.1 9.1 3.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Tetraspanin PF00335.20 KFP18542.1 - 2.2e-57 194.4 8.0 2.5e-57 194.2 8.0 1.0 1 0 0 1 1 1 1 Tetraspanin family RVT_1 PF00078.27 KFP18543.1 - 4.5e-05 23.1 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0444 PF15475.6 KFP18544.1 - 0.081 13.2 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Radial_spoke_3 PF06098.11 KFP18544.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 KH_6 PF15985.5 KFP18545.1 - 6.6e-17 61.6 0.0 1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 KH domain Dpy-30 PF05186.13 KFP18547.1 - 1.4e-13 50.3 0.0 1.5e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KFP18547.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit S-AdoMet_synt_C PF02773.16 KFP18548.1 - 3.9e-68 227.7 1.1 4.3e-68 227.6 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFP18548.1 - 1.6e-46 157.4 0.0 3.1e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFP18548.1 - 5.5e-44 148.9 0.1 1.3e-43 147.7 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KFP18548.1 - 0.035 12.9 0.2 0.091 11.5 0.2 1.6 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Lectin_C PF00059.21 KFP18550.1 - 2.2e-22 79.8 0.3 2.5e-22 79.7 0.3 1.0 1 0 0 1 1 1 1 Lectin C-type domain DUF5075 PF16825.5 KFP18550.1 - 0.0074 16.0 0.1 0.009 15.7 0.1 1.4 1 1 0 1 1 1 1 IGP family C-type lectin domain RasGEF PF00617.19 KFP18553.1 - 1.8e-46 158.5 3.2 1.8e-46 158.5 3.2 2.0 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFP18553.1 - 1.1e-12 48.1 0.1 4e-12 46.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif H2TH PF06831.14 KFP18553.1 - 0.055 13.5 0.0 24 5.0 0.0 3.1 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain CHGN PF05679.16 KFP18554.1 - 3.2e-84 283.6 0.2 4.1e-84 283.3 0.2 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP18554.1 - 1.7e-08 34.0 0.5 4.7e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase KfrA_N PF11740.8 KFP18554.1 - 0.00055 20.6 0.5 0.001 19.7 0.5 1.4 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Glyco_tranf_2_2 PF10111.9 KFP18554.1 - 0.0034 16.9 0.3 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DUF4407 PF14362.6 KFP18554.1 - 0.033 13.6 0.5 0.046 13.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 KFP18554.1 - 0.059 12.2 1.9 0.082 11.7 1.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Prefoldin PF02996.17 KFP18554.1 - 0.096 12.6 2.8 0.31 11.0 2.8 1.8 1 0 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.9 KFP18554.1 - 0.098 11.7 4.2 0.16 11.1 4.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KFP18554.1 - 0.15 12.7 2.9 0.39 11.4 2.9 1.7 1 0 0 1 1 1 0 SlyX Allexi_40kDa PF05549.11 KFP18554.1 - 0.15 11.6 0.7 0.25 10.8 0.7 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Csm1_N PF18504.1 KFP18554.1 - 0.16 12.3 4.9 0.36 11.2 4.4 1.8 2 0 0 2 2 1 0 Csm1 N-terminal domain Peptidase_M30 PF10460.9 KFP18554.1 - 0.17 10.8 0.0 0.34 9.8 0.0 1.5 2 0 0 2 2 2 0 Peptidase M30 FapA PF03961.13 KFP18554.1 - 0.26 9.9 2.8 0.38 9.3 2.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 KFP18554.1 - 0.79 10.2 3.3 1.7 9.1 3.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 KFP18554.1 - 1 9.5 5.6 0.56 10.4 3.3 1.6 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 KFP18554.1 - 1.5 9.1 8.8 3.5 7.9 8.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cnn_1N PF07989.11 KFP18554.1 - 2.6 8.3 8.2 1.3 9.3 5.6 1.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KFP18554.1 - 2.6 7.9 5.7 12 5.8 5.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Uso1_p115_C PF04871.13 KFP18554.1 - 7.3 7.0 18.5 0.061 13.7 7.2 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pkinase_Tyr PF07714.17 KFP18556.1 - 2e-104 348.4 0.0 2.9e-104 347.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RET_CLD3 PF17812.1 KFP18556.1 - 3.1e-54 182.2 0.1 7.1e-54 181.0 0.1 1.7 1 0 0 1 1 1 1 RET Cadherin like domain 3 RET_CLD1 PF17756.1 KFP18556.1 - 9.5e-54 181.0 0.0 2.4e-52 176.4 0.0 3.0 3 0 0 3 3 3 1 RET Cadherin like domain 1 Pkinase PF00069.25 KFP18556.1 - 5.7e-46 157.0 0.0 1.2e-45 156.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RET_CLD4 PF17813.1 KFP18556.1 - 2.8e-44 149.7 0.3 1.3e-43 147.6 0.2 2.3 2 0 0 2 2 2 1 RET Cadherin like domain 4 Cadherin PF00028.17 KFP18556.1 - 6e-19 68.3 0.3 4.6e-09 36.6 0.0 5.1 4 1 0 4 4 4 2 Cadherin domain Cadherin_2 PF08266.12 KFP18556.1 - 0.0099 15.7 0.3 0.96 9.3 0.0 2.9 3 0 0 3 3 3 1 Cadherin-like RIO1 PF01163.22 KFP18556.1 - 0.029 13.9 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KFP18556.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP18556.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIBIOP_C PF04950.12 KFP18557.1 - 2.2e-96 322.7 0.0 2.2e-96 322.7 0.0 3.3 4 0 0 4 4 4 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFP18557.1 - 8.3e-31 105.9 0.3 5.1e-30 103.4 0.0 2.7 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KFP18557.1 - 2.3e-05 24.0 2.8 0.00061 19.4 0.0 3.7 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP18557.1 - 0.0037 17.3 0.3 0.036 14.1 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP18557.1 - 0.015 15.7 0.0 0.053 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KFP18557.1 - 0.019 15.4 0.1 0.059 13.8 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP18557.1 - 0.049 14.2 1.7 1.7 9.2 0.1 3.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFP18557.1 - 0.07 13.5 0.1 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KFP18557.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gly_acyl_tr_C PF08444.10 KFP18557.1 - 0.11 12.7 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region AAA_33 PF13671.6 KFP18557.1 - 0.63 10.2 3.7 1.8 8.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain DUF4499 PF14934.6 KFP18558.1 - 1.7e-30 105.1 6.1 1.9e-30 105.0 6.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) PALP PF00291.25 KFP18559.1 - 1.3e-58 198.7 0.3 1.6e-58 198.5 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_6 PF13740.6 KFP18559.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 ACT domain PLAC9 PF15205.6 KFP18560.1 - 3.3e-14 53.0 0.1 3.4e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Placenta-specific protein 9 Annexin PF00191.20 KFP18561.1 - 5.7e-103 337.0 12.0 8.5e-26 89.8 0.2 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFP18561.1 - 0.019 14.8 0.6 8.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Myb DNA-binding like zf-3CxxC_2 PF17180.4 KFP18562.1 - 3.3e-27 95.0 10.2 3.3e-27 95.0 10.2 1.8 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 KFP18562.1 - 2.8e-11 43.0 6.2 2.8e-11 43.0 6.2 3.1 4 0 0 4 4 4 1 Zinc knuckle UPF0515 PF15135.6 KFP18562.1 - 8.6e-05 22.0 4.8 0.00011 21.7 4.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 KFP18562.1 - 0.019 15.4 16.6 0.43 11.1 15.4 2.9 2 1 0 2 2 2 0 Zinc-binding domain zf-CHY PF05495.12 KFP18562.1 - 0.13 12.7 11.6 0.99 9.9 2.9 2.4 2 0 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 KFP18562.1 - 6.5 7.3 10.9 27 5.3 11.0 1.9 1 1 1 2 2 2 0 Cytochrome c3 Pro_isomerase PF00160.21 KFP18563.1 - 2.8e-46 157.7 0.2 3e-46 157.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MIZ PF02891.20 KFP18564.1 - 3.4e-23 81.1 4.5 3.4e-23 81.1 4.5 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFP18564.1 - 6.1e-06 26.0 1.2 6.1e-06 26.0 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 KFP18564.1 - 1.2 9.8 3.8 2.4 8.8 3.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S24e PF01282.19 KFP18568.1 - 6.8e-46 154.1 0.4 1.3e-45 153.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RNA_pol_Rpb1_1 PF04997.12 KFP18569.1 - 1.8e-94 316.6 1.8 3e-94 315.9 1.8 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFP18569.1 - 2.6e-88 295.9 0.2 3.9e-88 295.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFP18569.1 - 1e-74 250.3 0.1 1.9e-74 249.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFP18569.1 - 5e-42 143.5 0.0 9.8e-41 139.3 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFP18569.1 - 2.1e-32 111.2 0.0 8.1e-32 109.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Chordopox_RPO7 PF05864.12 KFP18569.1 - 0.82 10.0 2.8 61 4.0 0.2 3.5 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) dbPDZ_assoc PF16610.5 KFP18570.1 - 1.6e-44 150.0 9.8 1.6e-44 150.0 9.8 3.4 2 0 0 2 2 2 1 Unstructured region between two PDZ domains on Dlg5 PDZ PF00595.24 KFP18570.1 - 2.3e-42 143.2 9.1 4.3e-12 46.2 0.0 4.6 4 0 0 4 4 4 4 PDZ domain Takusan PF04822.13 KFP18570.1 - 2.8e-35 120.0 0.5 2.8e-35 120.0 0.5 6.4 4 2 1 5 5 5 1 Takusan PDZ_6 PF17820.1 KFP18570.1 - 6.6e-34 115.6 2.3 2.3e-10 40.2 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP18570.1 - 1.6e-22 79.6 1.7 9.5e-06 25.9 0.0 4.9 4 0 0 4 4 4 4 PDZ domain Guanylate_kin PF00625.21 KFP18570.1 - 1.3e-14 54.3 0.6 1.3e-14 54.3 0.6 4.2 4 3 2 6 6 6 1 Guanylate kinase SH3_1 PF00018.28 KFP18570.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Peptidase_U32_C PF16325.5 KFP18570.1 - 0.11 12.7 0.6 0.97 9.8 0.0 2.7 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain BK_channel_a PF03493.18 KFP18572.1 - 2.3e-33 114.3 0.1 5.1e-33 113.2 0.1 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KFP18572.1 - 3.9e-18 65.6 19.1 7.7e-18 64.6 19.1 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KFP18572.1 - 3.7e-14 52.5 2.9 3.7e-14 52.5 2.9 2.6 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 KFP18572.1 - 1.7e-05 25.0 0.1 0.00015 22.0 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Lig_chan PF00060.26 KFP18572.1 - 0.14 12.0 3.1 0.89 9.4 0.7 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel SR-25 PF10500.9 KFP18572.1 - 6 6.4 13.0 9.8 5.7 13.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.27 KFP18576.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_3 PF01596.17 KFP18579.1 - 2.4e-73 245.9 0.1 2.9e-73 245.6 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KFP18579.1 - 6.6e-14 52.8 0.0 1e-13 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP18579.1 - 6.6e-07 29.2 0.1 8.8e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP18579.1 - 7e-06 26.7 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFP18579.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KFP18579.1 - 0.00065 19.1 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFP18579.1 - 0.0023 17.9 0.0 0.02 14.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP18579.1 - 0.0061 17.2 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Porin_3 PF01459.22 KFP18580.1 - 1.2e-85 287.2 5.4 1.4e-85 287.0 5.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin PAP2_C PF14360.6 KFP18581.1 - 1.5e-27 96.0 10.2 1.5e-27 96.0 10.2 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 KFP18581.1 - 2.2e-11 44.0 0.0 3.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP18581.1 - 4e-06 26.8 0.0 8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 KFP18581.1 - 0.0024 17.7 11.9 0.0024 17.7 11.9 2.0 1 1 1 2 2 2 1 PAP2 superfamily SAM_PNT PF02198.16 KFP18581.1 - 0.027 14.4 0.2 0.26 11.3 0.0 2.6 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain PAP2_3 PF14378.6 KFP18581.1 - 0.23 11.1 18.0 0.054 13.2 14.3 1.8 1 1 1 2 2 2 0 PAP2 superfamily DSPc PF00782.20 KFP18582.1 - 1.1e-30 106.2 0.0 1.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP18582.1 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP18582.1 - 0.0022 18.3 0.0 0.0047 17.2 0.0 1.5 1 1 0 1 1 1 1 Rit1 DUSP-like domain DSPn PF14671.6 KFP18582.1 - 0.0027 18.1 0.0 0.0037 17.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 KFP18582.1 - 0.058 13.5 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate MOZ_SAS PF01853.18 KFP18583.1 - 6.5e-82 273.5 0.5 1.2e-81 272.7 0.5 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFP18583.1 - 8.2e-22 76.6 3.9 8.2e-22 76.6 3.9 3.1 3 0 0 3 3 3 1 MYST family zinc finger domain Linker_histone PF00538.19 KFP18583.1 - 4.6e-09 36.5 0.0 4.9e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 linker histone H1 and H5 family PHD PF00628.29 KFP18583.1 - 9.8e-09 35.0 22.6 3.2e-06 26.9 10.2 3.8 2 1 1 3 3 3 2 PHD-finger Acetyltransf_7 PF13508.7 KFP18583.1 - 0.0034 17.8 0.0 0.019 15.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PfkB PF00294.24 KFP18584.1 - 5.3e-74 249.2 0.3 6e-74 249.1 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFP18584.1 - 0.04 13.3 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Raf1_N PF18578.1 KFP18584.1 - 0.051 14.0 0.3 0.24 11.9 0.1 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain Adap_comp_sub PF00928.21 KFP18586.1 - 1.3e-61 208.3 0.1 1.6e-61 208.0 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFP18586.1 - 6e-06 26.3 0.2 6e-06 26.3 0.2 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain muHD PF10291.9 KFP18586.1 - 0.00033 20.2 0.0 0.00047 19.7 0.0 1.1 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Vinculin PF01044.19 KFP18587.1 - 0 1534.4 39.3 5.4e-292 971.6 18.0 2.0 1 1 1 2 2 2 2 Vinculin family CARD PF00619.21 KFP18587.1 - 0.12 12.5 1.0 1 9.4 0.1 3.1 3 0 0 3 3 3 0 Caspase recruitment domain Dynactin_p22 PF07426.11 KFP18587.1 - 0.19 11.5 14.2 1.1 9.0 0.0 5.1 5 1 0 5 5 5 0 Dynactin subunit p22 Hemerythrin PF01814.23 KFP18587.1 - 0.79 10.3 3.6 1.8e+02 2.7 0.0 4.8 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain SKA2 PF16740.5 KFP18587.1 - 7.8 6.3 27.1 6 6.7 2.2 6.5 6 1 0 6 6 6 0 Spindle and kinetochore-associated protein 2 DUF3736 PF12540.8 KFP18588.1 - 0.13 12.4 0.1 0.14 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) Trypsin PF00089.26 KFP18589.1 - 5.2e-67 225.9 0.4 6.8e-67 225.5 0.4 1.1 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP18589.1 - 6.3e-18 64.9 4.0 1.2e-17 63.9 4.0 1.5 1 0 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.6 KFP18589.1 - 1.3e-06 29.3 0.0 2.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP18589.1 - 0.0007 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) hEGF PF12661.7 KFP18589.1 - 0.0011 19.6 4.1 0.0015 19.0 1.3 3.1 2 1 0 2 2 2 1 Human growth factor-like EGF EGF PF00008.27 KFP18589.1 - 0.0029 17.9 5.7 0.0029 17.9 5.7 3.3 3 1 0 3 3 3 1 EGF-like domain EGF_2 PF07974.13 KFP18589.1 - 0.0044 17.4 8.1 0.0044 17.4 8.1 3.2 3 0 0 3 3 3 1 EGF-like domain DUF1505 PF07403.11 KFP18589.1 - 0.024 14.8 0.8 0.068 13.4 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) DUF316 PF03761.15 KFP18589.1 - 0.053 13.1 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 CHCH PF06747.13 KFP18591.1 - 5.2e-10 39.2 3.0 5.6e-10 39.1 3.0 1.0 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KFP18591.1 - 0.0063 16.7 0.7 0.0067 16.6 0.7 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Sec23_trunk PF04811.15 KFP18592.1 - 2.5e-90 302.3 0.1 3.5e-90 301.8 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFP18592.1 - 8.9e-27 92.9 0.0 2.1e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFP18592.1 - 4.4e-19 69.0 0.1 3.4e-18 66.2 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFP18592.1 - 2.9e-14 52.8 11.5 7e-14 51.6 11.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFP18592.1 - 7.5e-11 41.8 0.0 1.9e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Calsarcin PF05556.11 KFP18593.1 - 3.1e-11 43.3 4.3 0.0041 16.7 0.0 3.9 2 1 1 4 4 4 3 Calcineurin-binding protein (Calsarcin) PDZ PF00595.24 KFP18593.1 - 4.4e-07 30.1 0.1 1.3e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP18593.1 - 6.5e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.11 KFP18594.1 - 2.6e-103 345.0 0.1 3e-103 344.8 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) p47_phox_C PF08944.11 KFP18594.1 - 0.11 11.9 1.2 0.24 10.8 1.2 1.6 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain UCH PF00443.29 KFP18595.1 - 1.3e-21 77.3 0.1 3.6e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP18595.1 - 5.3e-07 29.5 3.2 5.3e-07 29.5 3.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EPO_TPO PF00758.18 KFP18595.1 - 0.031 14.3 0.5 0.076 13.0 0.5 1.6 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Metallophos PF00149.28 KFP18597.1 - 2.1e-36 126.4 0.0 3.2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Annexin PF00191.20 KFP18598.1 - 3.5e-100 328.1 9.0 1.2e-27 95.8 0.4 4.1 4 0 0 4 4 4 4 Annexin MitMem_reg PF13012.6 KFP18599.1 - 9.2e-24 84.0 0.8 1.1e-23 83.7 0.2 1.4 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFP18599.1 - 1.1e-08 35.0 0.5 2e-08 34.2 0.5 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SH3_1 PF00018.28 KFP18600.1 - 3.9e-39 132.0 0.7 9.4e-12 44.4 0.0 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KFP18600.1 - 1.1e-38 130.9 2.2 1.6e-14 53.5 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KFP18600.1 - 2.9e-30 103.7 0.3 2.6e-12 46.2 0.0 3.6 4 0 0 4 4 4 3 Variant SH3 domain Sorb PF02208.16 KFP18600.1 - 2.8e-19 68.7 1.0 7.4e-19 67.3 1.0 1.8 1 0 0 1 1 1 1 Sorbin homologous domain DUF4657 PF15552.6 KFP18601.1 - 4.8e-07 29.7 0.6 4.8e-07 29.7 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4657) Zona_pellucida PF00100.23 KFP18602.1 - 6.9e-55 186.6 0.2 9e-55 186.2 0.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.18 KFP18602.1 - 9.2e-10 38.2 6.5 2.5e-09 36.9 6.5 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain p450 PF00067.22 KFP18603.1 - 4.9e-153 510.2 0.1 5.6e-153 510.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CUB PF00431.20 KFP18604.1 - 4.8e-180 587.0 7.6 3.8e-39 133.4 0.2 5.2 5 0 0 5 5 5 5 CUB domain Astacin PF01400.24 KFP18604.1 - 1.4e-73 246.6 0.0 2.6e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KFP18604.1 - 2.1e-14 53.5 30.6 1.6e-08 34.7 11.7 3.4 4 0 0 4 4 2 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP18604.1 - 8.6e-12 44.8 9.2 3.9e-06 26.7 1.8 3.5 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP18604.1 - 1e-11 44.8 29.3 1.2e-06 28.6 9.0 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFP18604.1 - 5.5e-07 29.7 20.9 0.00086 19.4 3.6 3.1 2 1 0 2 2 2 2 EGF domain CUB_2 PF02408.20 KFP18604.1 - 9.2e-06 25.4 2.0 0.17 11.7 0.1 4.8 5 0 0 5 5 5 2 CUB-like domain EGF PF00008.27 KFP18604.1 - 1.5e-05 25.2 24.5 0.0018 18.5 8.5 2.9 2 0 0 2 2 2 2 EGF-like domain Reprolysin_4 PF13583.6 KFP18604.1 - 0.00053 19.7 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like hEGF PF12661.7 KFP18604.1 - 0.00078 20.0 18.9 0.039 14.6 3.9 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 KFP18604.1 - 0.0027 17.5 0.7 1 9.2 0.1 2.8 2 0 0 2 2 2 2 Matrixin DUF3558 PF12079.8 KFP18604.1 - 0.0039 17.2 5.4 3.3 7.7 0.0 4.1 3 1 0 4 4 4 2 Protein of unknown function (DUF3558) EMP70 PF02990.16 KFP18605.1 - 4.9e-161 536.9 21.0 5.9e-161 536.7 21.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.8 KFP18605.1 - 0.63 9.5 19.6 0.58 9.6 4.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) EVC2_like PF12297.8 KFP18605.1 - 0.75 8.4 1.8 15 4.2 0.0 2.2 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DBB PF14545.6 KFP18606.1 - 1.1e-52 177.6 0.1 1.9e-52 176.9 0.1 1.4 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, TIR_3 PF18567.1 KFP18606.1 - 6.4e-48 162.1 0.3 1.5e-47 160.9 0.3 1.7 1 0 0 1 1 1 1 Toll/interleukin-1 receptor domain SRP40_C PF05022.12 KFP18607.1 - 3.4e-28 98.3 4.3 3.4e-28 98.3 4.3 2.6 3 0 0 3 3 3 1 SRP40, C-terminal domain UDPGT PF00201.18 KFP18608.1 - 5.3e-108 362.0 0.0 6.1e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFP18608.1 - 0.00065 19.7 0.0 0.0018 18.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Pro_3_hydrox_C PF05373.11 KFP18608.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Homeodomain PF00046.29 KFP18609.1 - 9.2e-23 79.9 9.4 1.5e-22 79.2 9.4 1.3 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP18609.1 - 5.2e-08 32.5 0.6 5.2e-08 32.5 0.6 2.2 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 KFP18609.1 - 0.0037 17.1 0.6 0.0037 17.1 0.6 2.0 2 0 0 2 2 2 1 Homeobox KN domain Auxin_canalis PF05703.11 KFP18609.1 - 5.3 6.9 10.3 1 9.2 6.1 1.8 2 0 0 2 2 2 0 Auxin canalisation Sec7 PF01369.20 KFP18610.1 - 9.4e-66 221.0 0.2 1.7e-65 220.1 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFP18610.1 - 2.4e-25 89.3 6.3 2.4e-25 89.3 6.3 4.2 3 1 1 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFP18610.1 - 0.007 16.2 0.3 9.9 6.1 0.0 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF758 PF05527.11 KFP18610.1 - 0.009 16.0 0.1 0.028 14.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF1045 PF06299.12 KFP18610.1 - 0.035 14.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Frag1 PF10277.9 KFP18611.1 - 1.8e-45 155.2 7.8 2e-45 155.0 7.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFP18611.1 - 0.0016 18.1 11.5 0.0021 17.7 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF2768 PF10966.8 KFP18611.1 - 0.85 10.1 6.3 0.29 11.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Serinc PF03348.15 KFP18611.1 - 1.6 7.5 7.4 0.53 9.1 3.3 1.9 1 1 1 2 2 2 0 Serine incorporator (Serinc) VKOR PF07884.14 KFP18611.1 - 2.3 8.4 13.6 1.8 8.7 11.7 1.9 1 1 0 1 1 1 0 Vitamin K epoxide reductase family RHD_DNA_bind PF00554.22 KFP18612.1 - 3.3e-66 222.4 0.1 4.9e-66 221.9 0.1 1.3 1 0 0 1 1 1 1 Rel homology DNA-binding domain Ank_2 PF12796.7 KFP18612.1 - 1.9e-29 102.0 3.2 2.3e-12 47.3 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP18612.1 - 6.7e-29 96.7 7.0 0.0017 18.7 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFP18612.1 - 2.9e-27 93.9 16.1 2.5e-05 24.5 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 KFP18612.1 - 1.5e-26 92.4 2.4 1.8e-08 34.8 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP18612.1 - 1.1e-24 86.1 3.9 3.8e-07 30.2 0.1 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) RHD_dimer PF16179.5 KFP18612.1 - 3.1e-24 84.9 0.0 3.2e-23 81.7 0.0 2.3 1 1 0 1 1 1 1 Rel homology dimerisation domain Sec7 PF01369.20 KFP18613.1 - 3e-43 147.6 0.0 5.1e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFP18613.1 - 2.8e-37 127.7 0.1 7.6e-37 126.3 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFP18613.1 - 1.3e-12 48.2 0.0 2.9e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 PH domain LRR_4 PF12799.7 KFP18614.1 - 6.8e-08 32.7 1.3 0.02 15.3 0.0 5.0 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP18614.1 - 2e-07 30.5 6.6 0.38 10.9 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich repeat F-box PF00646.33 KFP18614.1 - 2.7e-06 27.1 1.3 2.7e-06 27.1 1.3 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFP18614.1 - 0.0035 17.2 1.8 0.017 15.0 1.8 2.2 1 0 0 1 1 1 1 F-box-like DUF1699 PF08004.11 KFP18614.1 - 0.072 12.8 0.7 3.4 7.3 0.0 3.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1699) CUE PF02845.16 KFP18615.1 - 0.0026 17.4 0.1 0.0055 16.4 0.1 1.6 1 0 0 1 1 1 1 CUE domain PAX PF00292.18 KFP18616.1 - 1.1e-33 115.8 0.4 1.9e-33 115.0 0.4 1.5 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.8 KFP18616.1 - 5.4e-24 84.5 5.8 1.2e-23 83.3 5.8 1.7 1 0 0 1 1 1 1 Paired-box protein 2 C terminal HTH_23 PF13384.6 KFP18616.1 - 0.00032 20.4 0.0 0.00081 19.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Homeodomain PF00046.29 KFP18616.1 - 0.00079 19.2 0.1 0.018 14.9 0.1 2.7 3 0 0 3 3 3 1 Homeodomain HTH_Tnp_IS1 PF12759.7 KFP18616.1 - 0.08 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Cupin_8 PF13621.6 KFP18618.1 - 7.5e-34 117.6 3.1 5e-33 114.9 3.1 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP18618.1 - 5.8e-05 22.7 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein NDUF_B8 PF05821.11 KFP18619.1 - 2e-72 242.7 7.6 2.2e-72 242.6 7.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2892 PF11127.8 KFP18619.1 - 0.18 11.8 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Sec16_C PF12931.7 KFP18620.1 - 3.2e-05 23.7 0.9 0.00041 20.1 0.9 2.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KFP18620.1 - 8.5e-05 23.3 7.0 0.11 13.4 0.0 4.3 4 1 0 4 4 4 2 WD domain, G-beta repeat Prp18 PF02840.15 KFP18620.1 - 0.033 14.3 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain wnt PF00110.19 KFP18621.1 - 1.5e-95 320.4 20.1 1.8e-95 320.1 20.1 1.0 1 0 0 1 1 1 1 wnt family FA_desaturase PF00487.24 KFP18622.1 - 3.8e-15 56.4 9.9 6.8e-15 55.6 9.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PKD_channel PF08016.12 KFP18623.1 - 1e-159 531.8 18.8 1e-159 531.8 18.8 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KFP18623.1 - 1.2e-28 100.0 27.8 1.2e-28 100.0 27.8 1.6 2 0 0 2 2 2 1 Ion transport protein Fer4_24 PF18109.1 KFP18623.1 - 7.5e-19 67.7 1.5 1.6e-18 66.7 1.5 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_8 PF13833.6 KFP18623.1 - 0.0016 18.2 1.9 0.048 13.5 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP18623.1 - 0.007 16.2 2.6 0.66 10.1 0.1 3.7 4 0 0 4 4 4 1 EF-hand domain Spc7_N PF15402.6 KFP18623.1 - 0.022 13.1 0.7 0.029 12.7 0.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 EF-hand_1 PF00036.32 KFP18623.1 - 0.055 13.0 7.1 0.15 11.7 0.2 3.6 4 0 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 KFP18623.1 - 0.27 11.7 2.1 2 8.9 0.9 2.7 1 1 2 3 3 3 0 EF-hand domain pair BLOC1_2 PF10046.9 KFP18624.1 - 3.9e-33 113.6 7.7 5.2e-33 113.2 7.7 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ParB PF08775.10 KFP18624.1 - 0.0023 18.4 1.3 0.0035 17.8 1.3 1.4 1 0 0 1 1 1 1 ParB family DUF948 PF06103.11 KFP18624.1 - 0.041 14.1 0.2 0.089 13.1 0.2 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KFP18624.1 - 0.051 14.0 0.3 0.11 13.0 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pox_Ag35 PF03286.14 KFP18624.1 - 0.2 11.4 1.0 0.23 11.2 1.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein XhlA PF10779.9 KFP18624.1 - 0.55 10.5 6.2 15 5.9 0.0 3.2 3 1 0 3 3 3 0 Haemolysin XhlA UPF0449 PF15136.6 KFP18624.1 - 1.9 9.0 4.8 15 6.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 p450 PF00067.22 KFP18625.1 - 4.3e-152 507.1 0.2 4.9e-152 506.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 RINGv PF12906.7 KFP18626.1 - 1.6e-15 57.0 16.7 4.5e-15 55.5 16.7 1.9 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.12 KFP18626.1 - 0.013 15.5 1.2 0.018 14.9 1.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component CAP-ZIP_m PF15255.6 KFP18627.1 - 2.9e-60 202.6 5.8 2.9e-60 202.6 5.8 2.8 2 0 0 2 2 2 1 WASH complex subunit CAP-Z interacting, central region Chisel PF15355.6 KFP18627.1 - 0.062 13.5 0.3 0.062 13.5 0.3 4.1 3 0 0 3 3 3 0 Stretch-responsive small skeletal muscle X protein, Chisel PSP94 PF05825.11 KFP18628.1 - 7.7e-19 68.1 5.6 7.9e-19 68.0 5.6 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.18 KFP18628.1 - 0.0026 18.0 5.9 0.0062 16.8 5.9 1.7 1 1 0 1 1 1 1 von Willebrand factor type C domain PSP94 PF05825.11 KFP18629.1 - 1.3e-22 80.1 8.5 1.5e-22 80.0 8.5 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) Pacifastin_I PF05375.13 KFP18629.1 - 0.0025 17.5 3.5 0.0025 17.5 3.5 1.7 2 0 0 2 2 2 1 Pacifastin inhibitor (LCMII) VWC PF00093.18 KFP18629.1 - 0.048 14.0 9.3 0.14 12.5 9.3 1.8 1 1 0 1 1 1 0 von Willebrand factor type C domain Annexin PF00191.20 KFP18630.1 - 4e-98 321.5 14.3 1.3e-25 89.2 0.1 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 KFP18630.1 - 0.00017 21.4 0.3 3.3 7.7 0.0 3.8 4 0 0 4 4 4 2 Myb DNA-binding like Sigma70_ner PF04546.13 KFP18630.1 - 0.00036 20.5 0.5 0.11 12.3 0.0 2.6 2 1 1 3 3 3 2 Sigma-70, non-essential region FeoB_Cyto PF17910.1 KFP18630.1 - 0.061 13.9 2.3 0.43 11.2 0.4 2.9 3 0 0 3 3 3 0 FeoB cytosolic helical domain GrpE PF01025.19 KFP18630.1 - 0.13 11.9 0.8 0.26 10.9 0.3 1.8 2 1 0 2 2 2 0 GrpE DUF445 PF04286.12 KFP18630.1 - 0.17 11.6 2.3 0.52 10.1 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) MnmE_helical PF12631.7 KFP18630.1 - 0.21 11.8 4.0 0.32 11.1 4.0 1.4 1 1 0 1 1 1 0 MnmE helical domain Ant_C PF05586.11 KFP18631.1 - 8.4e-45 151.3 1.4 1.3e-44 150.7 1.4 1.3 1 0 0 1 1 1 1 Anthrax receptor C-terminus region DUF3328 PF11807.8 KFP18631.1 - 0.021 14.6 0.4 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Anth_Ig PF05587.13 KFP18632.1 - 3.7e-43 146.0 1.1 7.5e-43 145.0 1.1 1.5 1 0 0 1 1 1 1 Anthrax receptor extracellular domain VWA PF00092.28 KFP18632.1 - 1.7e-19 70.7 0.0 2.4e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFP18632.1 - 0.00017 21.0 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein zf-C2H2_4 PF13894.6 KFP18633.1 - 0.00027 21.5 31.7 0.024 15.5 4.8 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP18633.1 - 0.0056 17.1 26.4 0.13 12.8 6.7 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type SET PF00856.28 KFP18633.1 - 0.014 15.8 1.5 0.043 14.2 0.0 2.4 2 1 0 2 2 2 0 SET domain zf-C2H2_2 PF12756.7 KFP18633.1 - 0.033 14.5 15.7 1.6 9.1 2.8 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFP18633.1 - 0.1 12.4 2.2 0.31 10.9 2.2 1.9 1 0 0 1 1 1 0 GAGA factor zf-C2H2_9 PF16293.5 KFP18633.1 - 0.13 12.1 5.0 0.71 9.8 0.6 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 KFP18633.1 - 0.32 11.5 4.1 1.1 9.8 4.1 1.9 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain CpXC PF14353.6 KFP18633.1 - 0.87 9.6 10.8 2.9 7.9 0.5 3.8 3 1 0 3 3 3 0 CpXC protein zf-C2H2_6 PF13912.6 KFP18633.1 - 7 6.8 21.5 0.32 11.1 2.4 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger Peptidase_S41_N PF11918.8 KFP18634.1 - 5.5e-121 398.5 10.8 1.6e-38 131.9 0.3 4.6 4 0 0 4 4 4 4 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Peptidase_S41 PF03572.18 KFP18634.1 - 3.6e-85 283.6 0.0 2.6e-25 88.9 0.0 4.5 4 1 1 5 5 5 4 Peptidase family S41 muHD PF10291.9 KFP18634.1 - 0.0034 16.9 0.0 1.7 8.0 0.0 3.1 3 0 0 3 3 3 2 Muniscin C-terminal mu homology domain TGF_beta PF00019.20 KFP18635.1 - 4.2e-29 101.6 0.4 9.6e-29 100.4 0.4 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP18635.1 - 9.7e-18 64.8 1.5 9.7e-18 64.8 1.5 2.3 2 1 0 2 2 2 1 TGF-beta propeptide TGF_beta PF00019.20 KFP18636.1 - 2.8e-30 105.4 0.4 7.2e-30 104.0 0.4 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain Stb3 PF10330.9 KFP18636.1 - 0.19 11.8 0.5 2.4 8.2 0.1 2.5 3 0 0 3 3 3 0 Putative Sin3 binding protein Y_phosphatase PF00102.27 KFP18639.1 - 2.9e-76 256.1 0.0 3.6e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP18639.1 - 0.00027 20.8 0.1 0.00046 20.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP18639.1 - 0.022 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFP18639.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family PDZ_6 PF17820.1 KFP18640.1 - 9.4e-13 47.8 0.0 1.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP18640.1 - 5.4e-09 36.3 0.0 8.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP18640.1 - 0.00012 22.3 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.25 KFP18641.1 - 2e-63 214.2 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18641.1 - 2.5e-29 102.4 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP18641.1 - 2.6e-07 30.2 0.2 4e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP18641.1 - 2.6e-05 23.7 0.1 4.8e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP18641.1 - 0.00045 19.9 0.2 0.00088 18.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP18641.1 - 0.0007 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF530 PF04409.12 KFP18641.1 - 0.046 12.1 0.0 0.091 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF530) FTA2 PF13095.6 KFP18641.1 - 0.048 13.3 0.1 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RhoGAP PF00620.27 KFP18642.1 - 3.3e-48 163.4 0.0 8.2e-48 162.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFP18642.1 - 7.3e-23 81.1 0.1 2.4e-22 79.4 0.0 1.9 2 0 0 2 2 1 1 PH domain PH_11 PF15413.6 KFP18642.1 - 1.1e-07 32.3 0.2 5.6e-05 23.5 0.2 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFP18642.1 - 0.00063 20.0 0.2 0.064 13.5 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain ATG16 PF08614.11 KFP18642.1 - 0.00097 19.4 11.9 0.0021 18.3 11.9 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FPP PF05911.11 KFP18642.1 - 0.0011 17.3 8.8 0.0015 16.8 8.8 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil PH_3 PF14593.6 KFP18642.1 - 0.0014 18.7 0.0 0.0063 16.6 0.0 2.0 2 0 0 2 2 2 1 PH domain PspA_IM30 PF04012.12 KFP18642.1 - 0.011 15.3 8.0 0.021 14.4 8.0 1.4 1 0 0 1 1 1 0 PspA/IM30 family RIH_assoc PF08454.11 KFP18642.1 - 0.05 13.5 0.6 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 RyR and IP3R Homology associated SLX9 PF15341.6 KFP18642.1 - 0.32 11.4 4.9 0.75 10.2 4.9 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PH_9 PF15410.6 KFP18642.1 - 0.54 10.6 3.6 18 5.8 0.2 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain CENP-Q PF13094.6 KFP18642.1 - 0.85 9.8 12.8 2 8.6 12.8 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 KFP18642.1 - 0.87 9.7 13.6 1.4 9.0 12.6 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KFP18642.1 - 1 9.7 5.6 2.3 8.5 5.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KFP18642.1 - 1.1 10.0 6.0 4 8.1 6.0 2.1 1 0 0 1 1 1 0 SlyX CENP-H PF05837.12 KFP18642.1 - 1.4 9.4 8.5 1.8 9.0 6.9 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF4337 PF14235.6 KFP18642.1 - 1.8 8.6 3.3 3.1 7.9 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Striatin PF08232.12 KFP18642.1 - 2.6 8.6 10.7 3.5 8.2 9.4 1.9 1 1 0 1 1 1 0 Striatin family Cep57_MT_bd PF06657.13 KFP18642.1 - 2.9 8.4 14.5 0.076 13.5 2.3 2.7 1 1 1 2 2 1 0 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 KFP18642.1 - 2.9 8.0 17.9 1 9.4 14.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.11 KFP18642.1 - 3.2 8.1 8.7 1.9 8.7 6.3 1.9 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 KFP18642.1 - 5.2 7.2 8.1 8.5 6.6 4.4 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KFP18642.1 - 7.4 6.7 17.4 18 5.4 17.3 1.7 1 1 0 1 1 1 0 Tropomyosin like RIX1 PF08167.12 KFP18644.1 - 0.0068 16.2 0.1 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Beach PF02138.18 KFP18645.1 - 1.5e-122 408.3 0.3 2.1e-122 407.8 0.3 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KFP18645.1 - 7.8e-12 45.2 0.5 2.2e-11 43.8 0.5 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFP18645.1 - 1.6e-07 31.9 15.2 2e-05 25.3 0.1 5.6 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF4800 PF16057.5 KFP18645.1 - 0.12 11.6 1.0 0.23 10.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) LRR_8 PF13855.6 KFP18646.1 - 1.6e-17 63.0 16.6 2.3e-07 30.5 0.3 4.8 3 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP18646.1 - 4.1e-13 49.3 27.1 9.2e-06 25.9 0.2 5.2 2 1 6 8 8 8 6 Leucine Rich repeats (2 copies) LEDGF PF11467.8 KFP18646.1 - 2.7e-05 23.8 1.2 0.025 14.2 0.1 2.4 2 0 0 2 2 2 2 Lens epithelium-derived growth factor (LEDGF) LRR_1 PF00560.33 KFP18646.1 - 0.00019 21.5 18.6 13 6.8 0.0 7.2 6 2 0 6 6 6 3 Leucine Rich Repeat V-set PF07686.17 KFP18648.1 - 3e-09 37.0 0.1 8.1e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP18648.1 - 3.9e-06 27.0 0.0 2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP18648.1 - 1.6e-05 24.9 0.0 3.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP18648.1 - 8e-05 23.2 0.0 0.00037 21.0 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP18648.1 - 0.00022 21.5 0.1 0.011 16.0 0.1 2.5 1 1 0 1 1 1 1 Immunoglobulin domain Homeodomain PF00046.29 KFP18650.1 - 2.1e-21 75.5 1.6 3.6e-21 74.8 1.6 1.4 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP18650.1 - 1.7e-07 30.9 1.5 1.7e-07 30.9 1.5 1.9 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.11 KFP18650.1 - 0.0025 17.7 0.5 0.012 15.5 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain EspF PF04806.12 KFP18650.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.3 2 0 0 2 2 2 0 EspF protein repeat TGF_beta PF00019.20 KFP18651.1 - 3.3e-33 114.7 0.1 6.9e-33 113.7 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP18651.1 - 3.7e-22 79.3 0.6 5.1e-22 78.8 0.6 1.1 1 0 0 1 1 1 1 TGF-beta propeptide Disaggr_repeat PF06848.11 KFP18651.1 - 0.1 12.3 0.1 0.62 9.7 0.0 2.0 1 1 1 2 2 2 0 Disaggregatase related repeat SNF2_N PF00176.23 KFP18652.1 - 2e-73 247.1 0.5 6.4e-73 245.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP18652.1 - 7.3e-17 61.7 0.0 4.9e-16 59.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIF_beta PF02270.15 KFP18652.1 - 0.013 15.6 0.0 0.057 13.6 0.0 2.1 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain IL8 PF00048.20 KFP18653.1 - 1.5e-08 34.7 1.9 1.9e-08 34.3 1.9 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like TMEM72 PF16054.5 KFP18654.1 - 5.4e-82 273.9 0.9 6.4e-82 273.7 0.9 1.1 1 0 0 1 1 1 1 Transmembrane protein family 72 Cytochrom_B_N_2 PF13631.6 KFP18654.1 - 0.032 14.2 0.6 0.051 13.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Abhydrolase_1 PF00561.20 KFP18655.1 - 3.6e-27 95.6 0.1 4.6e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP18655.1 - 7.9e-22 76.6 0.1 1.8e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP18655.1 - 2.6e-05 23.6 0.0 0.0034 16.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KFP18655.1 - 0.073 12.7 0.1 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KFP18656.1 - 1.4e-22 80.6 0.2 1.5e-21 77.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP18656.1 - 1.6e-15 56.4 0.1 3.7e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP18656.1 - 0.0073 15.6 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ank_2 PF12796.7 KFP18657.1 - 1.2e-24 86.7 0.9 2.5e-12 47.2 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP18657.1 - 8.6e-23 80.1 3.0 2e-10 40.7 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP18657.1 - 2.8e-21 75.0 3.3 5.5e-06 26.6 0.0 5.7 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFP18657.1 - 1.1e-20 73.7 3.4 5.7e-06 26.8 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18657.1 - 4.6e-17 60.4 4.2 4.8e-05 23.4 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat USP8_dimer PF08969.11 KFP18658.1 - 3.3e-15 56.3 0.0 4.1e-15 56.0 0.0 1.2 1 1 0 1 1 1 1 USP8 dimerisation domain TPR_8 PF13181.6 KFP18658.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Actin PF00022.19 KFP18659.1 - 7.6e-150 499.0 0.0 2.5e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin Death PF00531.22 KFP18660.1 - 1.3e-13 50.9 0.0 3.2e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Death domain TNFR_c6 PF00020.18 KFP18660.1 - 3.8e-13 49.6 27.5 4.8e-10 39.7 3.2 4.5 4 0 0 4 4 4 2 TNFR/NGFR cysteine-rich region FA_hydroxylase PF04116.13 KFP18663.1 - 1.7e-24 86.7 18.7 1.7e-24 86.7 18.7 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_1 PF00561.20 KFP18664.1 - 2e-27 96.4 0.4 2.6e-27 96.1 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFP18664.1 - 4.1e-24 83.9 0.0 8.9e-24 82.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFP18664.1 - 6.1e-09 35.5 0.0 4.2e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KFP18664.1 - 0.003 17.2 0.1 0.031 13.9 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KFP18664.1 - 0.043 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KFP18664.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPR_2 PF07719.17 KFP18665.1 - 4.4e-26 88.8 31.3 7.3e-06 25.7 0.0 10.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFP18665.1 - 2.5e-22 77.7 1.2 2.2e-05 24.9 0.3 8.1 6 1 3 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFP18665.1 - 2.1e-20 71.6 28.2 1.2e-06 28.1 0.0 10.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP18665.1 - 5.7e-20 71.4 14.7 0.00016 21.9 0.2 7.2 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP18665.1 - 2.2e-19 67.9 32.2 0.00058 19.9 0.0 9.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP18665.1 - 1.3e-18 66.4 16.1 6.7e-06 25.7 0.2 7.8 7 1 1 8 8 8 4 TPR repeat TPR_17 PF13431.6 KFP18665.1 - 1.6e-17 62.5 19.4 0.063 13.7 0.0 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFP18665.1 - 2e-17 63.5 4.7 0.00014 22.3 0.3 6.4 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFP18665.1 - 8.4e-14 51.9 5.3 0.00023 21.7 0.7 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFP18665.1 - 1.1e-10 41.1 9.8 0.11 12.4 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP18665.1 - 7.2e-10 38.2 8.7 0.072 13.2 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP18665.1 - 1.2e-09 38.1 7.5 0.2 12.4 0.4 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFP18665.1 - 2e-09 37.1 8.1 0.00011 21.5 0.2 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP18665.1 - 2.7e-06 27.5 23.0 0.063 13.5 0.2 6.2 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KFP18665.1 - 9.3e-06 24.8 0.1 9.3e-06 24.8 0.1 4.1 3 1 2 5 5 5 1 NMDA receptor-regulated protein 1 SPOB_a PF14689.6 KFP18665.1 - 0.00015 21.4 0.9 0.3 10.8 0.1 3.9 3 0 0 3 3 3 1 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_9 PF13371.6 KFP18665.1 - 0.00039 20.5 0.2 22 5.3 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP18665.1 - 0.00073 19.0 1.5 1.8 7.9 0.0 4.0 3 1 1 5 5 5 1 MalT-like TPR region IF-2B PF01008.17 KFP18665.1 - 0.0082 15.4 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Mad3_BUB1_I_2 PF17014.5 KFP18665.1 - 0.0086 16.2 9.6 2.5 8.2 1.3 3.8 3 0 0 3 3 3 1 Putative Mad3/BUB1 like region 1 protein DUF4810 PF16068.5 KFP18665.1 - 0.018 15.6 12.8 0.7 10.5 0.9 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4810) PPR PF01535.20 KFP18665.1 - 0.019 15.2 5.1 7.5 7.0 0.0 4.7 5 0 0 5 5 4 0 PPR repeat RPN7 PF10602.9 KFP18665.1 - 0.074 12.7 8.5 0.5 10.1 0.4 4.1 4 0 0 4 4 4 0 26S proteasome subunit RPN7 BRICHOS PF04089.14 KFP18665.1 - 0.077 13.2 0.1 0.26 11.5 0.1 1.9 1 0 0 1 1 1 0 BRICHOS domain MIT PF04212.18 KFP18665.1 - 0.078 13.1 15.1 2.9 8.0 0.2 5.7 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain NSF PF02071.20 KFP18665.1 - 0.12 13.2 7.3 4.2 8.6 0.6 4.0 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat CNP_C_terminal PF17839.1 KFP18665.1 - 0.18 12.6 6.0 10 6.9 0.0 3.1 2 1 1 3 3 3 0 C-terminal domain of cyclic nucleotide phosphodiesterase Fis1_TPR_C PF14853.6 KFP18665.1 - 0.45 10.6 8.1 1.4 9.0 0.1 4.3 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat MFS_1 PF07690.16 KFP18666.1 - 1.3e-34 119.7 32.7 2.2e-20 72.9 7.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Gate PF07670.14 KFP18666.1 - 4.5 7.6 11.7 3.5 7.9 3.1 3.4 2 2 0 2 2 2 0 Nucleoside recognition Fumble PF03630.14 KFP18667.1 - 6e-121 403.6 0.1 6.9e-121 403.4 0.1 1.0 1 0 0 1 1 1 1 Fumble SpoU_methylase PF00588.19 KFP18667.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 SpoU rRNA Methylase family RNase_P_p30 PF01876.16 KFP18668.1 - 1.3e-62 211.1 0.0 1.5e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Ank_2 PF12796.7 KFP18669.1 - 2e-28 98.8 1.1 3.4e-12 46.8 0.1 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP18669.1 - 9.2e-25 86.0 0.3 3.5e-06 27.2 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFP18669.1 - 9.4e-24 83.5 0.0 3.3e-09 37.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18669.1 - 1e-23 80.8 0.5 8.8e-06 25.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP18669.1 - 4.4e-23 81.0 1.8 1.9e-08 34.4 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) HlyU PF10115.9 KFP18669.1 - 0.026 14.6 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator HlyU RAWUL PF16207.5 KFP18671.1 - 4.9e-13 49.5 1.3 6.7e-12 45.9 0.0 2.9 3 0 0 3 3 3 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KFP18671.1 - 6.8e-10 38.6 10.8 6.8e-10 38.6 10.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP18671.1 - 6e-08 32.4 11.5 6e-08 32.4 11.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP18671.1 - 0.0001 22.2 11.3 0.0001 22.2 11.3 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP18671.1 - 0.00011 22.3 10.4 0.00011 22.3 10.4 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP18671.1 - 0.00014 22.1 9.6 0.00014 22.1 9.6 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KFP18671.1 - 0.00048 20.0 11.2 0.00048 20.0 11.2 3.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP18671.1 - 0.0011 18.8 9.1 0.0011 18.8 9.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFP18671.1 - 0.0035 17.1 7.1 0.0065 16.3 7.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KFP18671.1 - 0.004 17.3 5.3 0.004 17.3 5.3 2.7 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFP18671.1 - 0.015 15.6 8.4 0.076 13.3 8.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP18671.1 - 0.02 14.7 8.4 0.02 14.7 8.4 2.9 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 DUF678 PF05077.12 KFP18671.1 - 0.18 11.9 3.4 1.6 9.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-C3HC4_5 PF17121.5 KFP18671.1 - 0.42 10.5 7.3 1.5 8.8 7.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP18671.1 - 3.4 7.6 13.2 0.046 13.6 4.1 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Zn_Tnp_IS1595 PF12760.7 KFP18671.1 - 8.4 6.5 12.5 3.4 7.7 0.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain HECT PF00632.25 KFP18672.1 - 3.4e-77 260.0 0.1 3.5e-76 256.6 0.1 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TipE PF16972.5 KFP18672.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE CBM_21 PF03370.13 KFP18674.1 - 1.9e-33 115.0 2.8 2.7e-33 114.5 2.8 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP18674.1 - 3.2e-16 59.7 1.4 6.4e-16 58.7 1.4 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Ank_5 PF13857.6 KFP18675.1 - 3.4e-102 333.1 34.7 1.1e-13 51.1 0.2 13.9 5 5 8 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 KFP18675.1 - 6.6e-101 326.7 45.5 9.2e-08 32.2 0.2 18.0 18 0 0 18 18 18 15 Ankyrin repeat Ank_4 PF13637.6 KFP18675.1 - 1.4e-98 322.1 22.0 6.5e-13 48.9 0.2 13.6 6 5 7 14 14 14 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP18675.1 - 5.1e-98 321.8 31.1 6.9e-15 55.4 0.1 9.8 5 5 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP18675.1 - 9.2e-87 274.5 24.9 1.6e-06 28.0 0.1 18.1 19 0 0 19 19 19 14 Ankyrin repeat PARP PF00644.20 KFP18675.1 - 1e-25 90.5 4.1 3.1e-23 82.4 4.1 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 KFP18675.1 - 1.2e-13 50.9 0.1 3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP18675.1 - 3e-11 43.6 0.1 7e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vps39_1 PF10366.9 KFP18675.1 - 0.0025 18.1 0.8 4.3 7.7 0.0 3.4 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 7tm_1 PF00001.21 KFP18676.1 - 2.1e-58 197.7 8.4 3e-58 197.2 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP18676.1 - 4.9e-08 32.7 4.9 2.3e-07 30.5 4.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP18676.1 - 5.5e-07 29.5 9.3 2.2e-06 27.5 2.4 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP18676.1 - 2.8e-06 26.9 1.4 5.3e-06 26.0 1.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP18676.1 - 0.081 12.6 5.8 0.027 14.2 2.6 1.8 2 1 0 2 2 2 0 Olfactory receptor RabGAP-TBC PF00566.18 KFP18678.1 - 1.7e-49 168.4 0.0 3.2e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PI-PLC-Y PF00387.19 KFP18679.1 - 2.9e-34 117.8 0.0 7.3e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RA PF00788.23 KFP18679.1 - 2.9e-23 82.3 0.0 1.3e-18 67.4 0.1 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.30 KFP18679.1 - 2.5e-09 37.4 0.0 4.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain EamA PF00892.20 KFP18680.1 - 0.0013 18.9 0.5 0.0013 18.9 0.5 1.0 1 0 0 1 1 1 1 EamA-like transporter family Phage_holin_4_2 PF04020.13 KFP18680.1 - 0.049 14.3 0.3 0.054 14.2 0.3 1.1 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV EPTP PF03736.17 KFP18681.1 - 1.4e-72 239.4 21.5 7.1e-13 48.3 0.1 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.6 KFP18681.1 - 1.5e-21 75.9 10.9 2.4e-14 52.8 4.9 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFP18681.1 - 5.2e-09 36.3 7.9 6.5e-05 23.2 2.9 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP18681.1 - 5.7e-08 32.8 0.9 5.7e-08 32.8 0.9 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP18681.1 - 0.0028 17.2 0.3 0.0087 15.6 0.3 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRRCT PF01463.24 KFP18681.1 - 0.058 14.0 0.0 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 KFP18681.1 - 0.95 10.3 10.3 2.8 8.8 0.8 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Fra10Ac1 PF09725.9 KFP18682.1 - 1.5e-52 176.9 5.9 3.8e-52 175.6 5.9 1.7 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 SelP_N PF04592.14 KFP18682.1 - 0.014 14.8 5.3 0.026 13.9 5.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Reovirus_cap PF00979.17 KFP18682.1 - 0.42 9.7 2.4 0.62 9.2 2.4 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 DUF4692 PF15763.5 KFP18682.1 - 2.9 8.3 6.8 5.2 7.5 6.8 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF755 PF05501.11 KFP18682.1 - 5.9 7.2 21.0 0.33 11.2 15.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FAM176 PF14851.6 KFP18682.1 - 8.6 6.0 11.8 11 5.7 5.7 2.6 2 0 0 2 2 2 0 FAM176 family PDEase_I PF00233.19 KFP18683.1 - 3.4e-81 272.5 3.1 3.4e-81 272.5 3.1 2.4 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFP18683.1 - 6.2e-25 88.4 0.0 2.6e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFP18683.1 - 1.2e-11 45.1 0.0 4.4e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFP18683.1 - 9.7e-06 26.0 0.0 0.089 13.1 0.0 2.7 2 1 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFP18683.1 - 0.014 15.5 3.5 0.49 10.5 0.0 3.3 4 0 0 4 4 4 0 Stage V sporulation protein T C-terminal, transcription factor FPL PF09758.9 KFP18683.1 - 0.046 13.7 1.9 0.26 11.3 1.0 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein EABR PF12180.8 KFP18685.1 - 3.6e-17 61.7 1.4 9.6e-17 60.3 1.4 1.8 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 CC2-LZ PF16516.5 KFP18685.1 - 0.00032 21.0 17.6 0.00032 21.0 17.6 5.6 1 1 4 5 5 5 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF99 PF01949.16 KFP18685.1 - 2 7.8 4.2 1.1 8.6 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF99 ADIP PF11559.8 KFP18685.1 - 6.2 6.9 71.3 0.049 13.7 20.2 5.3 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding C2 PF00168.30 KFP18686.1 - 3.1e-100 329.3 2.6 7.2e-19 68.0 0.0 8.5 7 1 0 7 7 7 7 C2 domain FerB PF08150.12 KFP18686.1 - 2e-31 108.4 0.1 4.6e-31 107.2 0.1 1.7 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 KFP18686.1 - 4.2e-29 101.5 1.7 3.9e-25 88.6 0.1 2.5 1 1 1 2 2 2 2 Ferlin C-terminus FerA PF08165.11 KFP18686.1 - 2.1e-23 82.1 0.2 4.3e-23 81.0 0.2 1.6 1 0 0 1 1 1 1 FerA (NUC095) domain FerI PF08151.12 KFP18686.1 - 1.5e-10 41.0 0.1 3.7e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain PI3K_C2 PF00792.24 KFP18686.1 - 0.0025 17.7 0.1 0.59 10.0 0.0 2.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF812 PF05667.11 KFP18686.1 - 0.011 14.7 1.0 0.017 14.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) p450 PF00067.22 KFP18687.1 - 1.1e-53 182.7 0.0 1.2e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec15 PF04091.12 KFP18688.1 - 9.2e-84 281.5 5.6 9.2e-84 281.5 5.6 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like AKAP7_NLS PF10469.9 KFP18688.1 - 0.0035 17.3 0.4 0.0035 17.3 0.4 2.6 3 0 0 3 3 3 1 AKAP7 2'5' RNA ligase-like domain Vps53_N PF04100.12 KFP18688.1 - 0.0035 16.4 5.5 0.0069 15.4 5.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF883 PF05957.13 KFP18688.1 - 0.018 15.6 1.0 11 6.8 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Sec8_exocyst PF04048.14 KFP18688.1 - 0.26 11.2 2.9 0.26 11.2 0.4 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain I_LWEQ PF01608.17 KFP18688.1 - 0.32 11.2 3.7 2.8 8.2 0.2 3.4 4 0 0 4 4 4 0 I/LWEQ domain COG2 PF06148.11 KFP18688.1 - 1.2 9.3 8.4 1.1 9.4 3.1 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KFP18688.1 - 2.8 8.1 9.0 0.1 12.8 0.8 2.9 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Homeodomain PF00046.29 KFP18689.1 - 0.00014 21.7 7.6 0.00034 20.4 7.6 1.7 1 0 0 1 1 1 1 Homeodomain zf-CW PF07496.15 KFP18689.1 - 0.11 12.5 0.9 0.22 11.6 0.9 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Kinesin PF00225.23 KFP18690.1 - 3.7e-115 384.4 0.2 3.7e-115 384.4 0.2 3.1 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bind PF13931.6 KFP18690.1 - 3.6e-49 166.6 5.6 3.6e-49 166.6 5.6 4.7 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding Microtub_bd PF16796.5 KFP18690.1 - 1.6e-23 83.3 0.0 1.3e-22 80.3 0.0 2.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KFP18690.1 - 2 8.8 4.8 40 4.5 0.0 3.6 4 1 0 4 4 4 0 AAA ATPase domain Peptidase_M16_M PF16187.5 KFP18691.1 - 2.5e-99 332.1 6.1 2.5e-99 332.1 6.1 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFP18691.1 - 3.8e-48 163.2 0.2 3.3e-46 157.0 0.1 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP18691.1 - 9e-40 136.6 0.1 8.1e-22 78.1 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Tn916-Xis PF09035.10 KFP18691.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Excisionase from transposon Tn916 RINGv PF12906.7 KFP18692.1 - 1.5e-14 53.9 10.9 2.2e-14 53.3 10.9 1.3 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.9 KFP18692.1 - 0.0011 18.7 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.6 KFP18692.1 - 0.0024 18.2 6.6 0.0055 17.0 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KFP18692.1 - 0.041 14.0 5.7 0.09 13.0 5.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KFP18692.1 - 0.44 10.4 6.0 0.95 9.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.13 KFP18692.1 - 0.5 10.1 3.2 1.1 9.0 3.2 1.5 1 1 0 1 1 1 0 CSL zinc finger PHD PF00628.29 KFP18692.1 - 1.3 9.0 8.6 2.2 8.2 8.6 1.4 1 0 0 1 1 1 0 PHD-finger RRM_7 PF16367.5 KFP18693.1 - 9.2e-38 128.3 0.0 6.4e-36 122.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFP18693.1 - 1.8e-20 72.9 5.8 5e-20 71.5 5.8 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFP18693.1 - 1e-11 44.5 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFP18693.1 - 0.037 13.8 0.6 0.087 12.6 0.6 1.6 1 0 0 1 1 1 0 U1 zinc finger SKG6 PF08693.10 KFP18693.1 - 0.33 10.4 4.4 0.68 9.4 4.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-B_box PF00643.24 KFP18693.1 - 0.34 11.1 5.8 0.88 9.8 5.8 1.6 1 0 0 1 1 1 0 B-box zinc finger EPL1 PF10513.9 KFP18693.1 - 1.8 8.9 7.4 8.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF3535 PF12054.8 KFP18695.1 - 2.1e-133 445.8 8.1 5.7e-130 434.4 6.3 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KFP18695.1 - 5.4e-58 196.4 0.0 3e-57 193.9 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.22 KFP18695.1 - 2.9e-21 73.7 21.8 0.0052 16.9 0.0 13.0 12 1 0 12 12 12 5 HEAT repeat Helicase_C PF00271.31 KFP18695.1 - 2.3e-17 63.4 0.0 6.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.7 KFP18695.1 - 2.2e-11 44.2 0.1 0.015 15.8 0.0 5.4 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFP18695.1 - 2.9e-11 43.6 2.9 0.03 14.7 0.3 6.7 5 1 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 KFP18695.1 - 4.6e-05 23.8 13.5 0.0041 17.6 0.1 7.3 8 1 1 9 9 9 1 HEAT-like repeat Cnd1 PF12717.7 KFP18695.1 - 5.5e-05 23.3 6.1 0.3 11.1 0.2 5.0 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KFP18695.1 - 9.9e-05 22.6 0.2 3 8.2 0.0 6.2 5 1 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 KFP18695.1 - 0.033 14.3 2.8 0.87 9.7 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UME PF08064.13 KFP18695.1 - 0.4 10.6 4.4 44 4.0 0.0 4.9 4 1 0 4 4 4 0 UME (NUC010) domain Cyclin_N PF00134.23 KFP18699.1 - 1.2e-19 70.3 1.5 2.2e-19 69.4 0.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP18699.1 - 1.8e-19 70.0 0.4 1.8e-19 70.0 0.4 3.1 3 0 0 3 3 3 2 Cyclin, C-terminal domain zf-C2H2 PF00096.26 KFP18700.1 - 0.0018 18.6 51.4 0.3 11.6 0.3 7.6 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFP18700.1 - 0.046 13.5 0.3 0.046 13.5 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain SH2 PF00017.24 KFP18701.1 - 2.4e-11 43.6 0.1 4.8e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 SH2 domain DNA_pol_B_thumb PF14791.6 KFP18703.1 - 2.1e-18 66.2 0.4 6.6e-18 64.6 0.4 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFP18703.1 - 1.3e-16 60.1 0.1 2.5e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFP18703.1 - 7.4e-12 45.5 0.0 3.4e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 KFP18703.1 - 3.3e-08 33.7 0.0 8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT PF00533.26 KFP18703.1 - 1.5e-06 28.5 0.0 3.8e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KFP18703.1 - 0.00028 21.1 0.0 0.00081 19.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.8 KFP18703.1 - 0.022 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus BRCT_2 PF16589.5 KFP18703.1 - 0.023 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Sulfotransfer_1 PF00685.27 KFP18707.1 - 2.3e-32 112.5 0.1 3.2e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP18707.1 - 1.1e-12 48.8 0.0 2.3e-08 34.7 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family LRR_8 PF13855.6 KFP18708.1 - 4.1e-15 55.3 2.6 4.1e-15 55.3 2.6 2.3 2 1 0 2 2 2 1 Leucine rich repeat 7tm_2 PF00002.24 KFP18708.1 - 1.1e-12 47.7 7.8 2.1e-12 46.9 7.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) I-set PF07679.16 KFP18708.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain GPS PF01825.21 KFP18708.1 - 3.7e-08 33.8 0.1 3.7e-08 33.8 0.1 3.4 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 KFP18708.1 - 2.4e-07 31.0 9.8 4.9e-05 23.6 3.2 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) HRM PF02793.22 KFP18708.1 - 5.9e-05 23.3 1.4 5.9e-05 23.3 1.4 2.5 3 0 0 3 3 3 1 Hormone receptor domain LRR_1 PF00560.33 KFP18708.1 - 0.00092 19.4 5.5 0.17 12.5 0.1 4.2 3 0 0 3 3 3 1 Leucine Rich Repeat ig PF00047.25 KFP18708.1 - 0.0018 18.4 0.1 0.0038 17.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_5 PF13306.6 KFP18708.1 - 0.0026 17.7 0.9 0.016 15.2 0.1 2.6 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Pex24p PF06398.11 KFP18708.1 - 0.029 13.4 0.0 0.029 13.4 0.0 2.0 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin Peptidase_M14 PF00246.24 KFP18712.1 - 3.9e-80 269.7 0.1 5e-80 269.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KFP18712.1 - 1e-14 54.5 0.4 1.8e-14 53.7 0.4 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP18712.1 - 2.3e-09 37.1 0.0 3.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KFP18712.1 - 0.025 13.7 0.2 0.06 12.4 0.2 1.6 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family RhoGEF PF00621.20 KFP18713.1 - 8e-20 71.8 0.9 9.3e-20 71.6 0.9 1.0 1 0 0 1 1 1 1 RhoGEF domain CutC PF03932.14 KFP18714.1 - 1.2e-57 194.7 0.0 2.4e-57 193.7 0.0 1.4 2 0 0 2 2 2 1 CutC family COX15-CtaA PF02628.15 KFP18715.1 - 2.4e-90 302.9 3.4 2.7e-90 302.7 3.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF4807 PF16065.5 KFP18715.1 - 0.046 13.4 0.1 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4807) GDA1_CD39 PF01150.17 KFP18716.1 - 6e-52 176.7 0.0 4.3e-34 117.9 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Mito_carr PF00153.27 KFP18717.1 - 1.7e-40 136.9 1.3 1.3e-20 73.1 0.6 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein SAT PF16073.5 KFP18717.1 - 0.0043 16.8 0.1 0.0048 16.7 0.1 1.3 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis NDUF_B6 PF09782.9 KFP18717.1 - 0.048 13.8 0.1 0.048 13.8 0.1 1.8 1 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Serine_protease PF18405.1 KFP18717.1 - 0.2 10.8 2.2 1.1 8.3 1.7 2.2 1 1 1 2 2 2 0 Gammaproteobacterial serine protease Glyco_hydro_79n PF03662.14 KFP18718.1 - 1.3e-21 76.9 0.1 1.7e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain DUF4723 PF15851.5 KFP18719.1 - 0.0027 17.8 9.5 0.0036 17.4 9.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4723) DUF4497 PF14924.6 KFP18719.1 - 0.085 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Activin_recp PF01064.23 KFP18719.1 - 1.4 10.1 15.6 2 9.6 15.6 1.3 1 1 0 1 1 1 0 Activin types I and II receptor domain Toxin_TOLIP PF00087.21 KFP18719.1 - 2.1 8.6 16.6 4.4 7.6 16.7 1.5 1 1 0 1 1 1 0 Snake toxin and toxin-like protein PRY PF13765.6 KFP18720.1 - 1.1e-19 69.8 0.3 1.6e-18 66.1 0.1 2.2 2 0 0 2 2 2 1 SPRY-associated domain SPRY PF00622.28 KFP18720.1 - 1e-15 57.9 0.4 1.4e-15 57.4 0.4 1.2 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 KFP18720.1 - 0.0095 15.9 0.0 0.011 15.7 0.0 1.3 1 1 0 1 1 1 1 Neuralized TSC22 PF01166.18 KFP18721.1 - 0.0039 17.5 0.9 0.0054 17.0 0.9 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family ZapB PF06005.12 KFP18721.1 - 0.017 15.5 1.3 0.027 14.9 1.3 1.3 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 KFP18721.1 - 0.071 13.3 1.8 0.26 11.5 1.8 1.9 1 1 0 1 1 1 0 Homeobox associated leucine zipper YabA PF06156.13 KFP18721.1 - 0.077 13.6 0.7 0.17 12.6 0.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Gtr1_RagA PF04670.12 KFP18722.1 - 6.8e-63 212.1 2.4 8.9e-63 211.7 2.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KFP18722.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 KFP18722.1 - 0.037 14.2 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Utp11 PF03998.13 KFP18724.1 - 1.9e-54 185.2 17.5 2.2e-54 185.0 17.5 1.0 1 0 0 1 1 1 1 Utp11 protein LIM PF00412.22 KFP18725.1 - 4.9e-49 164.4 70.2 2.1e-12 47.1 5.5 5.1 5 0 0 5 5 5 5 LIM domain RhoGAP PF00620.27 KFP18726.1 - 2.9e-26 92.1 0.0 6.5e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KFP18726.1 - 2.3e-16 60.0 0.0 3.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2 PF00096.26 KFP18727.1 - 6.3e-28 95.7 40.3 7.9e-05 22.9 1.3 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP18727.1 - 8e-26 89.3 44.7 1.5e-07 31.5 0.5 7.4 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP18727.1 - 1.1e-17 63.2 37.3 0.0077 17.0 0.9 7.0 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP18727.1 - 2.6e-10 40.4 22.5 0.00019 21.6 5.0 4.0 1 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP18727.1 - 5.2e-05 23.4 26.5 0.03 14.6 1.8 6.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP18727.1 - 0.0053 16.7 1.2 0.0053 16.7 1.2 5.6 6 0 0 6 6 6 3 C2H2-type zinc finger Marek_A PF02124.15 KFP18727.1 - 0.0091 15.9 2.1 0.34 10.7 0.2 2.7 2 1 1 3 3 3 1 Marek's disease glycoprotein A zf-C2H2_aberr PF17017.5 KFP18727.1 - 0.23 11.6 19.2 3.3 7.8 1.4 5.2 1 1 4 5 5 5 0 Aberrant zinc-finger Sua5_yciO_yrdC PF01300.18 KFP18728.1 - 1.3e-25 90.0 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination Ephrin_lbd PF01404.19 KFP18729.1 - 1.9e-69 233.3 0.0 3.3e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase_Tyr PF07714.17 KFP18729.1 - 1.4e-58 198.2 0.0 2.7e-58 197.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP18729.1 - 1.9e-21 76.6 0.0 6.9e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain SAM_1 PF00536.30 KFP18729.1 - 7e-16 58.4 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.6 KFP18729.1 - 1.4e-14 54.7 0.0 3.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.17 KFP18729.1 - 1.8e-14 53.6 0.0 4.3e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3 PF00041.21 KFP18729.1 - 0.00028 21.2 2.4 0.00072 19.9 0.1 2.7 3 1 0 3 3 3 1 Fibronectin type III domain Ephrin_rec_like PF07699.13 KFP18729.1 - 0.0056 16.4 1.4 0.0056 16.4 1.4 2.6 3 1 0 3 3 3 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 KFP18729.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Borealin PF10512.9 KFP18730.1 - 4.9e-28 97.6 0.1 7.2e-28 97.0 0.1 1.2 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 TLV_coat PF00429.19 KFP18731.1 - 0.0017 17.1 0.1 0.0019 17.0 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Meis_PKNOX_N PF16493.5 KFP18732.1 - 1.9e-39 133.9 1.4 3e-39 133.2 1.4 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KFP18732.1 - 1e-19 70.1 2.3 2.1e-19 69.1 2.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFP18732.1 - 5.5e-08 32.5 0.5 1.3e-07 31.4 0.5 1.6 1 0 0 1 1 1 1 Homeodomain TFIIA PF03153.13 KFP18732.1 - 0.021 14.8 2.9 0.037 14.0 2.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 KFP18732.1 - 0.024 14.9 0.7 0.052 13.8 0.7 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_pol_3_Rpc31 PF11705.8 KFP18732.1 - 0.032 14.5 6.7 0.06 13.6 6.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 KFP18732.1 - 0.085 12.7 2.0 0.13 12.1 2.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Med4 PF10018.9 KFP18732.1 - 0.1 12.3 6.1 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Voldacs PF03517.13 KFP18732.1 - 0.22 11.6 5.3 0.39 10.8 5.3 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 KFP18732.1 - 0.72 9.1 10.9 0.061 12.6 6.3 1.5 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.16 KFP18732.1 - 1.5 7.9 5.6 2.9 7.0 5.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KFP18732.1 - 4 5.4 13.5 1.7 6.7 10.8 1.6 2 0 0 2 2 2 0 DNA polymerase phi TT_ORF2 PF02957.15 KFP18732.1 - 5.5 7.9 8.5 1.9 9.4 5.4 1.9 2 0 0 2 2 1 0 TT viral ORF2 DUF4746 PF15928.5 KFP18732.1 - 6 6.2 8.5 12 5.2 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ig_3 PF13927.6 KFP18733.1 - 3.2e-16 59.7 0.0 1.5e-10 41.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP18733.1 - 2e-14 53.4 0.0 8.9e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP18733.1 - 5.9e-13 48.9 0.1 2.4e-09 37.3 0.0 2.9 2 1 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 KFP18733.1 - 1.1e-08 35.1 0.0 0.004 17.3 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP18733.1 - 2.6e-08 34.1 0.0 2.9e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KFP18734.1 - 2.9e-13 49.7 0.0 5.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP18734.1 - 7e-12 45.8 0.0 1.2e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP18734.1 - 7.7e-09 35.6 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.21 KFP18734.1 - 3e-08 33.9 0.2 0.0038 17.6 0.1 2.6 3 0 0 3 3 3 2 Fibronectin type III domain Ig_2 PF13895.6 KFP18734.1 - 6.7e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP18734.1 - 0.00011 22.3 0.0 0.035 14.3 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP18734.1 - 0.0025 17.8 0.0 0.0058 16.7 0.0 1.7 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP18734.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Innexin PF00876.18 KFP18735.1 - 2.7e-13 50.0 1.5 9.3e-13 48.2 1.5 1.7 1 1 0 1 1 1 1 Innexin Sensor PF13796.6 KFP18735.1 - 0.23 11.5 8.7 3.4 7.7 8.7 2.7 1 1 0 1 1 1 0 Putative sensor PseudoU_synth_2 PF00849.22 KFP18736.1 - 1.1e-35 123.1 0.0 1.8e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_1 PF01416.20 KFP18737.1 - 3.4e-34 117.6 0.0 2.3e-32 111.7 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase WD40_alt PF14077.6 KFP18737.1 - 0.015 15.1 1.5 0.015 15.1 1.5 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif 3-PAP PF12578.8 KFP18737.1 - 0.14 11.9 0.5 0.26 11.0 0.5 1.4 1 0 0 1 1 1 0 Myotubularin-associated protein BST2 PF16716.5 KFP18737.1 - 0.22 12.1 4.0 0.34 11.5 1.9 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HYLS1_C PF15311.6 KFP18738.1 - 5.2e-20 72.0 0.1 5.7e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus Ig_3 PF13927.6 KFP18739.1 - 2.9e-65 216.9 0.7 6.9e-18 65.0 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFP18739.1 - 4.5e-57 190.1 0.0 3.3e-13 49.5 0.0 6.3 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18739.1 - 1.8e-46 156.3 0.1 6.1e-09 36.1 0.0 6.1 4 2 1 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP18739.1 - 1.8e-41 140.2 0.0 4.6e-08 33.1 0.0 6.4 5 1 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.21 KFP18739.1 - 6.4e-38 129.0 5.0 1.7e-16 60.3 0.1 4.2 4 0 0 4 4 4 3 Fibronectin type III domain V-set PF07686.17 KFP18739.1 - 2.3e-24 85.7 10.5 3.4e-06 27.2 0.0 9.0 7 3 3 10 10 9 6 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP18739.1 - 7.8e-12 44.6 0.0 0.17 11.5 0.0 5.6 5 0 0 5 5 5 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP18739.1 - 2e-08 34.7 0.4 0.0073 16.9 0.0 3.7 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFP18739.1 - 1e-06 28.7 0.0 1.6 8.8 0.0 5.7 5 1 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFP18739.1 - 3.2e-06 27.5 0.0 0.33 11.4 0.0 5.4 6 0 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP18739.1 - 0.00018 21.7 0.0 30 5.0 0.0 5.6 6 0 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain Tissue_fac PF01108.17 KFP18739.1 - 0.0067 16.3 0.0 0.31 10.9 0.0 3.1 3 0 0 3 3 3 1 Tissue factor Herpes_gE PF02480.16 KFP18739.1 - 0.023 13.5 0.0 6.8 5.3 0.0 3.9 4 1 0 5 5 5 0 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.12 KFP18739.1 - 0.027 14.5 0.1 1.6 8.8 0.0 3.5 4 0 0 4 4 3 0 Penicillin-Binding Protein C-terminus Family EphA2_TM PF14575.6 KFP18739.1 - 0.052 14.4 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Interfer-bind PF09294.10 KFP18739.1 - 0.15 12.4 0.1 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III TNFR_16_TM PF18422.1 KFP18739.1 - 0.21 11.6 2.1 0.43 10.6 2.1 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Fer4_2 PF12797.7 KFP18739.1 - 0.73 10.1 3.7 1.7 8.9 3.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain STT3 PF02516.14 KFP18740.1 - 1.2e-164 548.9 42.9 1.1e-159 532.5 38.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KFP18740.1 - 1.1e-06 29.0 15.6 1.1e-06 29.0 15.6 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2985 PF11204.8 KFP18740.1 - 0.28 11.4 7.0 0.36 11.0 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) SRP-alpha_N PF04086.13 KFP18742.1 - 2.1e-57 195.3 9.3 2.8e-57 194.9 9.3 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFP18742.1 - 1.4e-48 165.2 0.4 1.2e-47 162.1 0.4 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFP18742.1 - 3.7e-10 39.9 0.3 2.2e-09 37.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFP18742.1 - 7.8e-08 31.6 0.0 1.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KFP18742.1 - 0.00088 19.3 0.0 0.029 14.4 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KFP18742.1 - 0.0077 16.0 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFP18742.1 - 0.023 14.9 0.0 0.097 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KFP18742.1 - 0.029 13.6 0.4 0.7 9.0 0.0 2.6 3 0 0 3 3 3 0 Anion-transporting ATPase NTPase_1 PF03266.15 KFP18742.1 - 0.04 13.8 0.3 0.52 10.2 0.0 2.6 2 1 0 2 2 2 0 NTPase Fer4_NifH PF00142.18 KFP18742.1 - 0.05 13.0 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KFP18742.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain SIR2_2 PF13289.6 KFP18743.1 - 2.9e-23 82.6 0.2 5.4e-23 81.7 0.1 1.5 2 0 0 2 2 2 1 SIR2-like domain RFC1 PF08519.12 KFP18743.1 - 0.14 12.3 0.1 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain TIR_2 PF13676.6 KFP18744.1 - 1.2e-19 71.0 0.0 1.8e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KFP18744.1 - 6e-08 32.7 0.0 7.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 TIR domain DcpS_C PF11969.8 KFP18745.1 - 1.2e-31 109.5 0.9 2.9e-31 108.3 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KFP18745.1 - 3.4e-14 53.6 0.1 7.4e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF2145 PF09916.9 KFP18745.1 - 0.035 13.8 0.3 0.087 12.5 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) CENP-B_N PF04218.13 KFP18745.1 - 0.068 12.8 0.0 0.24 11.0 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Glyco_transf_29 PF00777.18 KFP18746.1 - 1.2e-64 218.3 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Ig_3 PF13927.6 KFP18747.1 - 1.5e-46 156.9 0.6 3.9e-11 43.4 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFP18747.1 - 2.3e-42 143.0 0.1 8.3e-12 45.0 0.0 5.8 5 2 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18747.1 - 1.5e-36 124.6 0.1 3.9e-07 30.3 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP18747.1 - 2.2e-24 85.4 2.4 5.2e-05 23.3 1.1 5.7 5 1 0 5 5 5 4 Immunoglobulin domain C2-set_2 PF08205.12 KFP18747.1 - 6.9e-13 48.5 0.1 4e-07 30.0 0.0 4.3 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP18747.1 - 3.3e-12 46.6 0.8 0.46 10.7 0.0 7.2 5 3 1 6 6 6 3 Immunoglobulin V-set domain C1-set PF07654.15 KFP18747.1 - 3.8e-06 27.2 0.0 0.0044 17.4 0.0 4.3 5 1 0 5 5 4 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFP18747.1 - 1.7e-05 25.0 0.0 0.013 15.7 0.0 4.4 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP18747.1 - 2.7e-05 24.5 0.0 1.1 9.7 0.0 5.0 5 0 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Mid2 PF04478.12 KFP18747.1 - 0.034 14.0 0.2 0.087 12.7 0.1 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Izumo-Ig PF16706.5 KFP18747.1 - 0.053 13.6 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP18747.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Ets PF00178.22 KFP18749.1 - 7.6e-37 125.7 1.4 1.5e-36 124.7 1.4 1.5 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP18749.1 - 1.2e-34 118.2 0.2 2.2e-34 117.2 0.2 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.17 KFP18749.1 - 0.11 13.2 0.0 0.46 11.1 0.0 2.0 2 0 0 2 2 2 0 HSF-type DNA-binding Ets PF00178.22 KFP18750.1 - 2.9e-36 123.8 0.4 7.1e-36 122.5 0.4 1.7 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 KFP18750.1 - 4.6e-26 90.6 0.1 1.1e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain IRK_C PF17655.1 KFP18751.1 - 8.8e-75 250.1 0.1 1.2e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP18751.1 - 9.1e-58 194.1 2.5 1.3e-57 193.6 2.5 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP18751.1 - 0.025 14.5 9.1 0.077 13.0 9.1 1.8 1 1 0 1 1 1 0 Ion channel HSP70 PF00012.20 KFP18752.1 - 6.4e-265 880.0 12.3 7.2e-265 879.8 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFP18752.1 - 1.4e-18 66.8 0.5 3.9e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFP18752.1 - 0.0014 19.0 4.3 1.5 9.3 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KFP18752.1 - 0.0018 18.1 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KFP18752.1 - 0.012 15.2 0.1 4.8 6.6 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 KFP18752.1 - 0.033 13.2 0.3 0.18 10.8 0.3 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HORMA PF02301.18 KFP18752.1 - 0.08 12.5 1.2 0.2 11.2 1.2 1.6 1 0 0 1 1 1 0 HORMA domain MetOD2 PF18548.1 KFP18752.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.0 2 1 1 3 3 3 0 Metanogen output domain 2 MutS_III PF05192.18 KFP18752.1 - 7.5 6.7 6.6 29 4.8 2.9 2.5 2 1 0 2 2 2 0 MutS domain III V-set PF07686.17 KFP18753.1 - 1.1e-16 60.9 0.7 1.1e-12 48.1 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 KFP18753.1 - 2.5e-16 59.5 0.0 5.2e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP18753.1 - 2.1e-14 53.5 0.0 1.1e-05 25.5 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP18753.1 - 7.4e-14 52.1 2.3 2.7e-07 31.1 0.1 3.3 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KFP18753.1 - 2.3e-10 40.6 0.4 7e-07 29.5 0.1 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KFP18753.1 - 0.00034 20.1 0.1 0.023 14.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Amnionless PF14828.6 KFP18753.1 - 0.032 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless FAM176 PF14851.6 KFP18753.1 - 0.057 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Ig_C17orf99 PF17736.1 KFP18753.1 - 0.059 13.4 0.2 2.1 8.4 0.1 2.7 2 1 0 2 2 2 0 C17orf99 Ig domain SMN PF06003.12 KFP18753.1 - 0.061 12.6 1.1 0.11 11.8 1.1 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zip PF02535.22 KFP18753.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OSTbeta PF15048.6 KFP18753.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PT-VENN PF04829.13 KFP18753.1 - 0.19 11.8 0.7 10 6.3 0.0 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Miga PF10265.9 KFP18753.1 - 0.3 10.0 3.0 0.4 9.6 2.6 1.4 1 1 0 1 1 1 0 Mitoguardin Herpes_pp85 PF04637.12 KFP18753.1 - 0.38 9.1 3.2 0.55 8.6 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3446 PF11928.8 KFP18753.1 - 8 6.8 13.1 21 5.5 13.1 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain VASt PF16016.5 KFP18754.1 - 2.1e-37 128.9 2.0 3.3e-37 128.3 2.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KFP18754.1 - 2.2e-28 98.4 0.1 4e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain V-set PF07686.17 KFP18755.1 - 4.6e-20 71.8 0.1 5.8e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP18755.1 - 0.00042 20.4 0.4 0.00099 19.2 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP18755.1 - 0.00051 20.1 0.1 0.001 19.1 0.1 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP18755.1 - 0.00065 20.2 0.4 0.0017 18.9 0.4 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP18755.1 - 0.0011 19.2 0.2 0.003 17.9 0.2 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFP18755.1 - 0.026 14.1 0.0 0.072 12.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain Ac76 PF05814.11 KFP18755.1 - 0.056 13.5 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) EII-GUT PF03608.13 KFP18755.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor E1-E2_ATPase PF00122.20 KFP18756.1 - 7.7e-44 149.4 1.3 7.7e-44 149.4 1.3 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP18756.1 - 1.2e-42 145.7 2.2 1.2e-42 145.7 2.2 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFP18756.1 - 2.3e-26 91.7 0.0 4.6e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP18756.1 - 4.5e-20 72.8 0.0 1.1e-10 42.2 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP18756.1 - 8.6e-15 54.2 0.0 1.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFP18756.1 - 1.1e-06 28.6 2.2 0.0004 20.2 1.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP18756.1 - 0.017 15.5 0.1 0.12 12.8 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.16 KFP18756.1 - 0.063 12.8 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_transf_43 PF03360.16 KFP18757.1 - 4.1e-75 252.1 0.0 4.7e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_hydro_35 PF01301.19 KFP18758.1 - 4.7e-108 361.6 0.1 5.9e-108 361.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFP18758.1 - 1.3e-15 57.6 0.1 3.9e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KFP18758.1 - 0.0001 22.8 0.2 0.012 16.2 0.0 2.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DUF4434 PF14488.6 KFP18758.1 - 0.15 12.0 0.0 0.52 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Acyl-CoA_dh_1 PF00441.24 KFP18759.1 - 6.1e-46 156.3 5.2 8.7e-46 155.8 5.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP18759.1 - 1e-29 103.5 0.0 2.4e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP18759.1 - 4.1e-25 87.8 0.0 8.6e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP18759.1 - 8.8e-22 77.8 2.3 1.3e-21 77.2 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_dehyd_C PF12186.8 KFP18759.1 - 0.12 12.6 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal EVE PF01878.18 KFP18760.1 - 2.1e-50 170.5 0.0 3.5e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 EVE domain Vps26 PF03643.15 KFP18761.1 - 5.3e-118 393.0 4.6 6.3e-118 392.8 4.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Ig_3 PF13927.6 KFP18762.1 - 9.4e-23 80.6 4.5 3e-13 50.2 1.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP18762.1 - 1.8e-20 72.8 0.6 9.4e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP18762.1 - 4.2e-14 52.6 2.6 2.2e-08 34.2 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP18762.1 - 6.2e-14 52.1 4.5 1.2e-09 38.4 1.4 2.7 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP18762.1 - 5.3e-13 49.0 2.5 3.1e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KFP18762.1 - 6.7e-06 26.1 0.2 0.001 19.1 0.0 2.7 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFP18762.1 - 6.1e-05 23.0 0.6 0.0087 16.1 0.1 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP18762.1 - 0.00014 22.1 1.7 0.088 13.2 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.15 KFP18762.1 - 0.17 11.7 4.6 0.31 10.8 4.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RVT_1 PF00078.27 KFP18763.1 - 0.0013 18.3 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sam68-YY PF16568.5 KFP18765.1 - 4.5e-18 65.7 33.6 9.1e-18 64.8 33.6 1.5 1 0 0 1 1 1 1 Tyrosine-rich domain of Sam68 Qua1 PF16274.5 KFP18765.1 - 4.2e-07 29.7 4.1 4.2e-07 29.7 4.1 2.1 2 0 0 2 2 2 1 Qua1 domain KH_1 PF00013.29 KFP18765.1 - 4.8e-07 29.5 0.0 8.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 KH domain F-box-like PF12937.7 KFP18768.1 - 8.8e-14 51.1 0.7 8.8e-14 51.1 0.7 1.6 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KFP18768.1 - 3.2e-06 26.9 0.9 3.2e-06 26.9 0.9 2.5 2 1 1 3 3 3 1 F-box domain PH PF00169.29 KFP18769.1 - 4.3e-37 126.8 0.0 1.6e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 PH domain DEP PF00610.21 KFP18769.1 - 1.1e-13 51.0 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.6 KFP18769.1 - 3.4e-11 43.5 0.3 5e-05 23.6 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 KFP18769.1 - 7.1e-10 39.2 0.0 3.3e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KFP18769.1 - 7.3e-06 25.9 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP18769.1 - 0.00036 20.9 5.1 0.12 12.8 0.7 3.9 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFP18769.1 - 0.00043 20.5 0.2 0.023 15.0 0.0 3.3 2 2 1 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.10 KFP18769.1 - 0.0076 16.6 0.1 0.22 11.9 0.0 2.3 2 0 0 2 2 2 1 Plant pleckstrin homology-like region PH_16 PF17838.1 KFP18769.1 - 0.12 12.2 0.7 5.3 6.9 0.1 2.6 2 1 0 2 2 2 0 PH domain CNRIP1 PF15043.6 KFP18770.1 - 1e-67 226.6 0.0 1.1e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 EF-hand_1 PF00036.32 KFP18771.1 - 8.3e-28 93.8 14.2 1.2e-06 27.6 0.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KFP18771.1 - 5.7e-26 90.8 5.4 2.1e-14 53.7 0.5 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP18771.1 - 3.7e-22 76.3 6.6 1.3e-05 24.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFP18771.1 - 4.3e-22 76.6 9.5 2.5e-05 23.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFP18771.1 - 5.8e-19 67.7 7.4 0.0015 18.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP18771.1 - 5.5e-09 36.3 0.2 0.0015 18.9 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFP18771.1 - 1.8e-07 31.0 4.6 0.0075 16.2 0.2 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP18771.1 - 0.00065 20.0 0.2 0.079 13.3 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 KFP18771.1 - 0.029 14.3 3.1 9.7 6.1 0.1 3.4 2 2 2 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 KFP18771.1 - 9 6.6 9.8 15 5.9 2.9 3.3 2 2 1 3 3 3 0 Dockerin type I domain KH_8 PF17903.1 KFP18772.1 - 4e-05 23.6 0.1 6.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFP18772.1 - 0.00023 20.9 0.8 0.00056 19.7 0.8 1.6 1 0 0 1 1 1 1 KH domain WD40 PF00400.32 KFP18773.1 - 5.3e-13 49.2 3.5 0.00018 22.2 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP18773.1 - 0.00073 19.8 0.2 0.95 9.8 0.0 3.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Itfg2 PF15907.5 KFP18773.1 - 0.0023 17.1 0.4 0.037 13.1 0.1 2.4 1 1 1 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 eIF2A PF08662.11 KFP18773.1 - 0.017 15.0 0.2 6.6 6.6 0.1 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PHTB1_N PF14727.6 KFP18773.1 - 0.096 12.0 0.0 11 5.3 0.0 2.7 2 1 0 3 3 3 0 PTHB1 N-terminus Sas10_Utp3 PF04000.15 KFP18774.1 - 5.7e-17 62.1 0.4 9.4e-17 61.4 0.4 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF932 PF06067.11 KFP18774.1 - 0.018 14.8 1.0 0.02 14.7 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) ING PF12998.7 KFP18774.1 - 0.073 13.7 1.7 2.7 8.6 0.3 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ETAA1 PF15350.6 KFP18775.1 - 2.8e-255 849.7 42.1 5.2e-152 508.0 6.3 2.0 1 1 1 2 2 2 2 Ewing's tumour-associated antigen 1 homologue MAP1B_neuraxin PF00414.17 KFP18776.1 - 1.6e-17 62.2 112.5 0.0034 16.9 1.9 14.4 13 0 0 13 13 13 12 Neuraxin and MAP1B repeat MRP-S27 PF10037.9 KFP18777.1 - 3.7e-108 361.9 13.9 8.1e-108 360.7 13.9 1.5 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_1 PF12854.7 KFP18777.1 - 0.00015 21.4 0.1 0.00054 19.6 0.1 1.9 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 KFP18777.1 - 0.00036 20.7 0.0 0.0011 19.2 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 KFP18777.1 - 0.0035 17.5 0.0 0.016 15.5 0.0 2.2 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.6 KFP18777.1 - 0.016 15.3 0.1 0.044 13.9 0.1 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TPR_19 PF14559.6 KFP18777.1 - 0.052 14.1 0.0 0.3 11.6 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EMP24_GP25L PF01105.24 KFP18777.1 - 3.6 7.5 7.2 8.2 6.3 7.2 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PPR_2 PF13041.6 KFP18778.1 - 2.6e-08 33.9 0.1 8e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 PPR repeat family MRP-S27 PF10037.9 KFP18778.1 - 2.8e-07 29.8 4.0 6.4e-07 28.6 4.0 1.6 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR PF01535.20 KFP18778.1 - 3.3e-05 23.8 0.4 0.00021 21.3 0.2 2.5 2 0 0 2 2 2 1 PPR repeat DED PF01335.21 KFP18778.1 - 0.0019 18.5 7.6 0.46 10.8 0.3 3.9 4 0 0 4 4 4 2 Death effector domain TPR_11 PF13414.6 KFP18778.1 - 0.0056 16.3 0.0 0.66 9.7 0.0 3.2 3 0 0 3 3 3 1 TPR repeat PPR_3 PF13812.6 KFP18778.1 - 0.0094 16.0 3.6 0.023 14.7 0.0 2.7 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_8 PF13181.6 KFP18778.1 - 0.0094 16.1 0.3 26 5.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_long PF17177.4 KFP18778.1 - 0.016 14.5 0.4 6.7 6.0 0.2 2.6 1 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP DUF3627 PF12299.8 KFP18778.1 - 0.12 12.4 1.7 0.17 12.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) HEAT_EZ PF13513.6 KFP18779.1 - 5.2e-36 122.6 0.6 1.5e-12 47.7 0.0 10.8 8 2 4 12 12 11 4 HEAT-like repeat HEAT PF02985.22 KFP18779.1 - 1.3e-32 109.0 7.9 0.0031 17.7 0.0 11.7 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.6 KFP18779.1 - 3.6e-21 75.4 0.0 3.9e-06 27.2 0.0 6.5 5 2 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 KFP18779.1 - 5.9e-17 62.2 1.0 0.00011 22.3 0.7 4.5 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KFP18779.1 - 2.5e-16 59.1 4.6 0.0073 16.3 0.0 7.8 8 0 0 8 8 7 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KFP18779.1 - 1.3e-15 57.0 0.1 8.1e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KFP18779.1 - 6.2e-15 55.6 1.3 0.0093 16.5 0.0 6.9 5 2 2 7 7 7 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFP18779.1 - 8.7e-11 41.1 5.7 0.0017 17.0 0.4 5.1 2 2 0 4 4 4 4 Adaptin N terminal region UNC45-central PF11701.8 KFP18779.1 - 1.2e-05 25.3 4.4 0.00084 19.3 0.4 3.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 KFP18779.1 - 0.00026 20.2 0.8 0.0011 18.2 0.0 2.3 2 1 0 2 2 2 1 Dopey, N-terminal RTP1_C1 PF10363.9 KFP18779.1 - 0.0004 20.5 0.4 0.03 14.5 0.1 3.8 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFP18779.1 - 0.00097 18.8 0.7 1.1 8.8 0.0 4.4 3 2 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 KFP18779.1 - 0.0012 18.9 2.1 3.5 7.7 0.4 4.8 4 1 0 4 4 4 1 Exportin 1-like protein MMS19_C PF12460.8 KFP18779.1 - 0.0064 15.7 5.2 0.71 8.9 0.1 4.3 2 2 1 4 4 4 2 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 KFP18779.1 - 0.0079 16.1 0.7 3.6 7.6 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) DUF3689 PF12463.8 KFP18779.1 - 0.023 14.0 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) Tti2 PF10521.9 KFP18779.1 - 0.034 13.7 1.3 37 3.7 0.0 4.7 3 3 2 5 5 5 0 Tti2 family Ecm29 PF13001.7 KFP18779.1 - 0.1 11.2 0.1 7.4 5.1 0.0 3.7 4 1 1 5 5 5 0 Proteasome stabiliser TAF6_C PF07571.13 KFP18779.1 - 0.12 12.7 0.0 3.4 8.1 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain TAFH PF07531.14 KFP18779.1 - 0.69 10.0 4.3 17 5.6 0.0 4.2 5 1 1 6 6 4 0 NHR1 homology to TAF muHD PF10291.9 KFP18781.1 - 5.6e-63 212.8 0.2 9.4e-63 212.1 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KFP18781.1 - 7.6e-19 67.8 0.0 7.6e-19 67.8 0.0 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1664 PF07889.12 KFP18781.1 - 0.074 13.1 9.9 0.16 12.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KFP18781.1 - 0.51 8.2 12.4 0.97 7.3 12.1 1.5 1 1 0 1 1 1 0 Prominin DUF445 PF04286.12 KFP18781.1 - 1.9 8.2 10.5 3.4 7.4 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TMEM171 PF15471.6 KFP18782.1 - 7.3e-156 518.1 1.4 8.2e-156 517.9 1.4 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 TMEM174 PF15029.6 KFP18782.1 - 0.038 13.7 5.0 2.1 8.0 1.7 3.2 2 1 0 2 2 2 0 Transmembrane protein 174 DUF2371 PF10177.9 KFP18782.1 - 0.28 11.4 0.4 4.3 7.5 0.5 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) PGF-CTERM PF18204.1 KFP18782.1 - 1.4 9.0 6.2 0.26 11.3 0.4 2.7 3 0 0 3 3 3 0 PGF-CTERM motif TMEM215 PF15746.5 KFP18782.1 - 4.4 6.7 4.9 10 5.5 0.6 2.7 3 0 0 3 3 3 0 TMEM215 family TMEM174 PF15029.6 KFP18783.1 - 6.7e-118 392.5 0.1 7.6e-118 392.4 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 174 NAC PF01849.18 KFP18784.1 - 2.8e-26 91.2 0.2 4.4e-26 90.6 0.2 1.3 1 0 0 1 1 1 1 NAC domain Myco_19_kDa PF05481.12 KFP18784.1 - 0.06 13.6 0.1 0.086 13.1 0.1 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen LolA PF03548.15 KFP18784.1 - 0.063 13.0 0.6 0.085 12.6 0.6 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Ank_2 PF12796.7 KFP18785.1 - 8.1e-27 93.6 0.1 2.7e-13 50.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP18785.1 - 3.9e-21 74.8 0.2 6.4e-07 29.5 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18785.1 - 2.2e-20 70.6 0.0 5.1e-06 26.4 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFP18785.1 - 3.5e-20 71.5 0.0 6.5e-06 26.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFP18785.1 - 2.2e-18 66.4 0.0 7.6e-09 36.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1296 PF06972.11 KFP18785.1 - 0.33 11.1 1.3 2.9 8.1 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) UTP15_C PF09384.10 KFP18786.1 - 7.8e-40 135.9 0.1 1.2e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KFP18786.1 - 7.3e-25 86.8 4.9 6.2e-06 26.9 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP18786.1 - 6.9e-12 45.5 0.0 0.0002 21.6 0.1 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFP18786.1 - 2.8e-05 24.1 0.0 0.074 13.1 0.0 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF4462 PF14692.6 KFP18787.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) SLC35F PF06027.12 KFP18788.1 - 1.3e-05 24.9 10.9 2e-05 24.3 10.9 1.4 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFP18788.1 - 5.4e-05 23.4 12.2 5.4e-05 23.4 12.2 3.2 2 2 0 2 2 2 1 EamA-like transporter family Trp_oprn_chp PF09534.10 KFP18788.1 - 0.16 11.8 0.1 9.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1418 PF07214.12 KFP18788.1 - 0.79 9.6 2.9 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF4619 PF15398.6 KFP18789.1 - 2.2e-102 342.6 3.4 2.4e-102 342.4 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) Acetyltransf_1 PF00583.25 KFP18790.1 - 9.9e-18 64.5 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP18790.1 - 5.5e-12 45.7 0.0 8.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP18790.1 - 6.6e-12 45.7 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFP18790.1 - 5.3e-09 35.9 0.0 9.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KFP18790.1 - 6.4e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFP18790.1 - 0.00014 22.5 0.0 0.00021 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFP18790.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TGS PF02824.21 KFP18790.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 TGS domain Adap_comp_sub PF00928.21 KFP18791.1 - 1.9e-37 129.1 0.0 2.3e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Sec10 PF07393.11 KFP18792.1 - 1.1e-152 510.1 30.7 1.1e-150 503.4 22.9 3.5 2 1 0 2 2 2 1 Exocyst complex component Sec10 V_ATPase_I PF01496.19 KFP18792.1 - 0.34 8.8 17.9 0.028 12.4 13.2 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 KFP18792.1 - 0.41 10.7 1.8 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 KFP18792.1 - 2.3 8.3 8.6 1.7 8.6 0.9 3.7 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMPIT PF07851.13 KFP18792.1 - 4.3 6.5 12.6 5.5 6.1 0.1 2.9 3 0 0 3 3 3 0 TMPIT-like protein EF-G-binding_N PF07299.11 KFP18792.1 - 4.8 7.8 10.9 4.4 7.9 2.9 3.6 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal Cnn_1N PF07989.11 KFP18792.1 - 7.5 6.8 13.3 5.3 7.3 1.6 3.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 BLOC1_2 PF10046.9 KFP18792.1 - 9.4 6.6 11.8 0.17 12.2 2.7 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 KFP18792.1 - 9.5 6.4 20.9 0.059 13.6 9.4 2.9 3 2 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF2723 PF11028.8 KFP18795.1 - 6.2e-37 127.1 4.3 6.2e-37 127.1 4.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) Pellino PF04710.14 KFP18796.1 - 2.7e-178 592.9 0.2 3e-178 592.7 0.2 1.0 1 0 0 1 1 1 1 Pellino Prok-RING_4 PF14447.6 KFP18796.1 - 0.0023 17.8 8.6 1 9.2 3.8 3.5 2 1 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP18796.1 - 0.15 11.9 13.5 0.37 10.7 1.4 3.4 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP18796.1 - 0.62 10.5 13.2 0.48 10.8 0.5 3.3 3 1 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.6 KFP18796.1 - 6.8 6.7 15.9 0.56 10.2 0.4 3.7 3 2 1 4 4 4 0 zinc-RING finger domain zf-RING_11 PF17123.5 KFP18796.1 - 9.4 6.1 7.8 57 3.6 0.1 3.6 3 0 0 3 3 3 0 RING-like zinc finger SEA PF01390.20 KFP18797.1 - 5.6e-23 81.1 7.4 2.2e-16 59.9 0.5 3.2 3 0 0 3 3 3 2 SEA domain EGF PF00008.27 KFP18797.1 - 0.00033 20.9 14.9 0.00035 20.8 4.0 2.4 2 0 0 2 2 2 2 EGF-like domain DUF4214 PF13946.6 KFP18797.1 - 0.0084 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) Dam PF05869.11 KFP18797.1 - 0.041 13.4 0.1 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Peptidase_C48 PF02902.19 KFP18798.1 - 2e-34 119.3 0.0 5.4e-34 117.9 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arb2 PF09757.9 KFP18799.1 - 4.2e-07 29.3 0.1 5.3e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain DUF676 PF05057.14 KFP18799.1 - 0.027 14.0 0.2 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) ATP-grasp_6 PF18419.1 KFP18799.1 - 0.11 12.1 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp-like domain DIM1 PF02966.16 KFP18800.1 - 4e-55 185.2 0.1 4.6e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KFP18800.1 - 7.7e-06 25.8 0.0 9.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin tRNA_m1G_MT PF01746.21 KFP18801.1 - 1.4e-31 109.7 0.0 2.1e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PCNP PF15473.6 KFP18802.1 - 3.4e-68 229.3 12.7 3.8e-68 229.1 12.7 1.0 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family SPATIAL PF15256.6 KFP18802.1 - 0.058 13.7 1.0 0.086 13.2 0.1 1.5 1 1 1 2 2 2 0 SPATIAL zf-H2C2_2 PF13465.6 KFP18803.1 - 1.4e-46 154.9 86.4 5.7e-08 32.8 0.2 13.9 14 0 0 14 14 14 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFP18803.1 - 1.4e-41 138.7 94.9 0.00019 21.7 0.9 13.3 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18803.1 - 1.4e-39 131.3 88.6 0.00074 20.2 1.4 13.5 13 0 0 13 13 13 12 C2H2-type zinc finger BTB PF00651.31 KFP18803.1 - 1.7e-22 79.7 1.8 1.7e-22 79.7 1.8 1.8 2 0 0 2 2 1 1 BTB/POZ domain zf-C2H2_6 PF13912.6 KFP18803.1 - 5.2e-16 58.2 92.7 0.0001 22.2 0.6 12.0 13 1 0 13 13 12 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP18803.1 - 7.7e-12 45.2 56.6 0.0021 18.3 0.6 12.4 12 0 0 12 12 11 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP18803.1 - 8e-07 29.3 51.1 0.001 19.3 0.7 8.2 4 2 4 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KFP18803.1 - 2.3e-05 24.7 70.8 0.84 10.0 0.6 12.1 3 1 10 13 13 13 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP18803.1 - 0.00026 21.3 61.0 0.32 11.5 0.4 11.5 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KFP18803.1 - 0.0048 16.7 14.7 11 6.0 0.1 7.6 6 1 1 7 7 7 0 C2H2 type zinc-finger (1 copy) HNH_5 PF14279.6 KFP18803.1 - 0.0052 16.6 1.3 0.0052 16.6 1.3 7.0 8 2 1 9 9 7 1 HNH endonuclease zf-C2H2_11 PF16622.5 KFP18803.1 - 0.0081 15.9 59.6 0.045 13.5 0.0 11.6 12 0 0 12 12 12 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFP18803.1 - 0.024 14.5 0.5 0.024 14.5 0.5 10.1 11 0 0 11 11 11 0 zinc-finger of a C2HC-type Ta0938 PF11494.8 KFP18803.1 - 0.068 13.5 17.2 0.81 10.0 0.7 5.3 3 3 2 6 6 6 0 Ta0938 SNRNP27 PF08648.12 KFP18803.1 - 0.37 10.9 2.6 9.2 6.4 0.8 2.9 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins PhnA_Zn_Ribbon PF08274.12 KFP18803.1 - 3.1 7.9 8.3 7.6 6.6 0.0 5.3 6 1 0 6 6 5 0 PhnA Zinc-Ribbon zinc_ribbon_15 PF17032.5 KFP18803.1 - 5.3 7.9 45.9 14 6.5 2.6 8.3 3 1 5 8 8 8 0 zinc-ribbon family zf-C2H2_8 PF15909.5 KFP18803.1 - 6.4 7.2 34.8 0.14 12.5 4.3 5.6 2 1 1 4 4 4 0 C2H2-type zinc ribbon Ribosomal_L24e PF01246.20 KFP18804.1 - 2.2e-15 56.6 0.5 2.2e-15 56.6 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DDHD PF02862.17 KFP18804.1 - 2.2 8.4 5.1 2.5 8.2 5.1 1.1 1 0 0 1 1 1 0 DDHD domain LRR_9 PF14580.6 KFP18805.1 - 1.2e-20 73.8 1.0 6.8e-16 58.3 0.0 2.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFP18805.1 - 2e-15 56.6 26.3 6.7e-05 23.2 3.2 5.0 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP18805.1 - 4.4e-13 48.8 26.1 8.3e-06 25.5 3.4 4.1 2 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KFP18805.1 - 0.0038 17.2 14.1 0.3 11.2 0.5 5.8 4 1 1 5 5 5 2 Leucine Rich repeat IQ PF00612.27 KFP18805.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif LRR_1 PF00560.33 KFP18805.1 - 0.12 12.9 12.0 2.6 8.9 0.2 5.8 4 1 1 5 5 5 0 Leucine Rich Repeat Neurexophilin PF06312.12 KFP18806.1 - 1.8e-47 161.5 0.0 2.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFP18806.1 - 8.3e-05 23.4 0.0 0.00017 22.4 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat Ank_2 PF12796.7 KFP18807.1 - 1.1e-24 86.8 8.9 2.8e-12 47.0 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP18807.1 - 1e-22 80.2 3.1 0.00015 22.2 0.0 5.8 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP18807.1 - 1.8e-21 75.6 8.5 0.00031 21.1 0.1 6.9 6 2 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFP18807.1 - 4.2e-18 63.6 3.6 0.07 13.7 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFP18807.1 - 1.7e-11 44.1 8.0 0.007 16.7 0.3 5.8 3 2 2 5 5 5 3 Ankyrin repeats (many copies) PD-C2-AF1 PF09310.10 KFP18807.1 - 0.0036 16.7 0.0 0.0089 15.5 0.0 1.6 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 Zn-C2H2_12 PF18112.1 KFP18807.1 - 0.81 10.2 3.4 16 6.1 0.1 3.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Zona_pellucida PF00100.23 KFP18808.1 - 7e-44 150.6 2.5 8.9e-44 150.2 2.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Ig_3 PF13927.6 KFP18809.1 - 3.7e-31 107.6 13.9 1.5e-08 35.1 0.0 6.5 5 2 1 6 6 6 6 Immunoglobulin domain Ig_2 PF13895.6 KFP18809.1 - 7.9e-26 90.2 7.1 1.2e-06 28.7 0.0 5.2 6 0 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 KFP18809.1 - 1.4e-23 82.7 4.7 5.6e-18 64.8 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain ig PF00047.25 KFP18809.1 - 3e-17 62.6 15.6 0.0013 18.9 0.6 7.4 5 3 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KFP18809.1 - 9.2e-16 57.7 16.8 0.0014 18.6 0.2 7.7 5 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.17 KFP18809.1 - 1.5e-10 41.2 12.3 0.002 18.3 0.0 7.1 5 4 2 7 7 7 2 Immunoglobulin V-set domain C1-set PF07654.15 KFP18809.1 - 2.8e-06 27.6 10.5 0.0024 18.2 0.1 4.7 5 1 1 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP18809.1 - 0.0002 20.9 0.4 0.14 11.7 0.0 3.2 4 0 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP18809.1 - 0.0061 16.6 0.3 1.2 9.2 0.0 3.6 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_C19orf38 PF17737.1 KFP18809.1 - 0.045 14.1 0.0 0.21 11.9 0.0 2.1 1 1 0 1 1 1 0 Ig domain in C19orf38 (HIDE1) Podoplanin PF05808.11 KFP18809.1 - 0.086 12.9 0.6 0.2 11.8 0.6 1.7 1 0 0 1 1 1 0 Podoplanin PepSY_TM PF03929.16 KFP18809.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region V-set_CD47 PF08204.11 KFP18809.1 - 1 9.3 5.4 11 6.0 0.0 3.9 4 1 1 5 5 5 0 CD47 immunoglobulin-like domain DUF2028 PF09667.10 KFP18810.1 - 3.3e-61 206.7 9.7 2.3e-60 203.9 9.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF2028) HMG_box PF00505.19 KFP18810.1 - 3.2e-17 62.7 0.8 9.7e-17 61.2 0.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP18810.1 - 4.6e-11 43.2 1.0 1.7e-10 41.3 1.0 2.1 1 0 0 1 1 1 1 HMG-box domain CD47 PF04549.14 KFP18811.1 - 6.5e-44 149.7 23.2 9e-44 149.2 23.2 1.2 1 0 0 1 1 1 1 CD47 transmembrane region V-set_CD47 PF08204.11 KFP18811.1 - 1.5e-35 122.0 0.0 2.2e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain V-set PF07686.17 KFP18811.1 - 0.00019 21.5 0.1 0.00033 20.8 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP18811.1 - 0.0032 18.0 0.0 0.006 17.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP18811.1 - 0.0043 17.2 0.5 0.018 15.2 0.5 1.9 1 1 0 1 1 1 1 Immunoglobulin domain MaAIMP_sms PF16951.5 KFP18811.1 - 0.0062 16.3 2.3 0.017 14.8 2.3 1.7 1 0 0 1 1 1 1 Putative methionine and alanine importer, small subunit I-set PF07679.16 KFP18811.1 - 0.0073 16.3 0.2 0.016 15.3 0.2 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18811.1 - 0.018 15.4 0.2 0.068 13.5 0.2 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Pox_I5 PF04713.12 KFP18811.1 - 0.044 13.8 1.4 0.044 13.8 1.4 2.7 2 1 0 2 2 2 0 Poxvirus protein I5 Claudin_2 PF13903.6 KFP18811.1 - 1.3 8.8 7.5 12 5.5 2.7 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction IFT57 PF10498.9 KFP18812.1 - 2.7e-136 454.3 4.8 3.1e-136 454.1 4.8 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Lipoprotein_20 PF13942.6 KFP18812.1 - 0.017 15.0 3.4 0.13 12.1 1.0 2.4 1 1 1 2 2 2 0 YfhG lipoprotein MCPsignal PF00015.21 KFP18812.1 - 0.025 14.4 1.3 0.052 13.4 1.2 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mod_r PF07200.13 KFP18812.1 - 0.14 12.2 13.6 0.45 10.6 5.9 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HAD_2 PF13419.6 KFP18812.1 - 0.15 12.2 3.3 0.21 11.7 2.1 1.8 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Cbl_N PF02262.16 KFP18812.1 - 0.19 11.7 2.1 0.63 10.1 0.6 2.2 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Med9 PF07544.13 KFP18812.1 - 1.3 9.2 7.7 0.19 11.9 2.3 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 KFP18812.1 - 2.2 7.6 6.8 4.8 6.4 6.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KFP18812.1 - 3.9 6.3 18.9 0.1 11.4 11.9 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein V-set PF07686.17 KFP18813.1 - 3.4e-25 88.3 6.1 9e-12 45.1 0.2 3.2 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP18813.1 - 5.2e-17 62.2 2.1 3.8e-05 24.2 0.1 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP18813.1 - 7.2e-15 54.9 5.9 1.2e-05 25.4 0.5 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP18813.1 - 8.1e-14 51.5 0.1 3.9e-05 23.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18813.1 - 1.4e-10 41.4 10.6 0.00073 19.8 1.2 4.4 2 2 1 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.11 KFP18813.1 - 2.8e-05 24.1 0.4 0.0068 16.4 0.0 2.3 2 0 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFP18813.1 - 9.9e-05 22.5 0.0 0.76 10.1 0.0 4.0 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP18813.1 - 0.00021 20.8 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_5 PF16681.5 KFP18813.1 - 0.00024 21.4 0.1 0.43 11.0 0.0 3.8 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP18813.1 - 0.00043 20.3 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFP18813.1 - 0.0095 16.0 0.0 0.036 14.1 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP18813.1 - 0.019 15.3 0.4 9.4 6.7 0.4 3.2 2 1 0 2 2 2 0 Immunoglobulin C1-set domain C2-set PF05790.15 KFP18813.1 - 0.03 14.5 0.0 4.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Myosin_head PF00063.21 KFP18814.1 - 5.6e-288 956.8 0.0 5.6e-288 956.8 0.0 2.8 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KFP18814.1 - 1.3e-158 529.9 258.9 1.6e-158 529.6 258.9 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KFP18814.1 - 3.1e-17 62.1 7.4 1e-16 60.5 7.4 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 KFP18814.1 - 0.0015 18.2 48.6 0.0015 18.2 48.6 8.1 1 1 5 7 7 7 3 Intermediate filament protein T3SSipB PF16535.5 KFP18814.1 - 0.0093 16.4 7.6 0.0093 16.4 7.6 10.8 3 1 10 13 13 13 1 Type III cell invasion protein SipB DUF1664 PF07889.12 KFP18814.1 - 0.024 14.7 144.1 0.037 14.1 8.4 13.4 3 3 8 13 13 13 0 Protein of unknown function (DUF1664) AAA_22 PF13401.6 KFP18814.1 - 0.07 13.4 0.0 0.07 13.4 0.0 5.7 5 2 2 7 7 7 0 AAA domain IQ PF00612.27 KFP18814.1 - 0.14 12.0 3.5 4.2 7.4 0.6 3.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP18814.1 - 0.24 11.7 0.0 0.24 11.7 0.0 5.8 4 2 0 5 5 5 0 AAA ATPase domain ATG16 PF08614.11 KFP18815.1 - 0.0013 19.0 31.9 0.0013 19.0 31.9 2.9 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 KFP18815.1 - 0.031 14.5 1.2 0.031 14.5 1.2 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF3584 PF12128.8 KFP18815.1 - 1.2 6.5 45.8 1.8 6.0 45.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Arm PF00514.23 KFP18815.1 - 2.1 8.5 9.3 1.3 9.1 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GAS PF13851.6 KFP18815.1 - 4 6.7 57.0 0.25 10.7 30.1 4.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KFP18815.1 - 4.1 7.5 60.4 1 9.5 20.6 4.8 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding zf-C2H2 PF00096.26 KFP18816.1 - 4.5e-49 162.2 83.5 5.1e-07 29.8 1.4 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP18816.1 - 1.5e-32 109.4 76.5 0.00082 20.0 0.6 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP18816.1 - 3.4e-27 93.6 80.0 2.9e-08 33.8 1.2 11.7 13 0 0 13 13 13 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP18816.1 - 1.6e-12 47.4 55.2 0.061 13.6 0.2 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP18816.1 - 8.8e-09 35.2 66.8 0.059 13.4 0.2 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP18816.1 - 2.3e-08 33.7 52.9 0.058 13.2 2.8 9.3 10 0 0 10 10 10 6 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KFP18816.1 - 3e-07 30.1 56.9 4.3e-05 23.2 2.4 8.4 9 1 0 9 9 8 5 C2H2-type zinc-finger domain zf-BED PF02892.15 KFP18816.1 - 0.00064 19.7 0.5 0.00064 19.7 0.5 7.9 3 3 5 8 8 8 3 BED zinc finger zf-met PF12874.7 KFP18816.1 - 0.0063 16.9 50.9 0.36 11.3 0.4 9.5 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP18816.1 - 0.019 15.2 41.7 0.57 10.5 10.5 5.4 2 1 3 5 5 5 0 C2H2-type zinc ribbon GAGA PF09237.11 KFP18816.1 - 0.046 13.5 19.6 2 8.3 0.4 5.8 3 1 2 5 5 5 0 GAGA factor zinc_ribbon_15 PF17032.5 KFP18816.1 - 0.2 12.4 0.2 0.2 12.4 0.2 6.5 3 1 2 7 7 7 0 zinc-ribbon family Ribosomal_L31 PF01197.18 KFP18816.1 - 0.4 10.9 9.5 5.9 7.2 1.2 4.7 3 1 1 4 4 4 0 Ribosomal protein L31 PDZ PF00595.24 KFP18817.1 - 8.7e-05 22.8 0.4 0.00031 21.0 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP18817.1 - 0.00021 21.1 0.1 0.00067 19.5 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP18817.1 - 0.075 13.4 0.3 0.2 12.0 0.3 1.8 1 1 0 1 1 1 0 PDZ domain Cadherin PF00028.17 KFP18818.1 - 0 2050.6 57.7 1.4e-24 86.3 0.5 34.6 34 1 0 34 34 34 34 Cadherin domain Cadherin_2 PF08266.12 KFP18818.1 - 3.3e-49 164.6 0.0 0.017 14.9 0.0 24.9 29 0 0 29 29 29 10 Cadherin-like Laminin_G_2 PF02210.24 KFP18818.1 - 2.1e-40 138.2 0.9 7.7e-19 68.5 0.0 3.4 3 0 0 3 3 2 2 Laminin G domain Laminin_G_1 PF00054.23 KFP18818.1 - 2.1e-33 115.3 0.1 1.9e-17 63.7 0.0 3.6 4 0 0 4 4 4 2 Laminin G domain Cadherin_3 PF16184.5 KFP18818.1 - 1.3e-31 108.9 63.4 0.25 11.4 0.1 27.1 29 1 1 30 30 30 11 Cadherin-like EGF PF00008.27 KFP18818.1 - 3.7e-21 75.1 76.6 1e-06 28.9 8.7 6.2 5 1 0 5 5 5 5 EGF-like domain EGF_CA PF07645.15 KFP18818.1 - 1.3e-10 41.3 25.9 2.9e-07 30.6 6.5 5.6 4 1 1 5 5 3 2 Calcium-binding EGF domain hEGF PF12661.7 KFP18818.1 - 5.1e-09 36.4 71.6 0.00028 21.4 7.6 7.6 7 0 0 7 7 7 4 Human growth factor-like EGF EGF_2 PF07974.13 KFP18818.1 - 0.00018 21.8 74.8 0.24 11.8 8.3 5.9 5 1 0 5 5 5 4 EGF-like domain EGF_3 PF12947.7 KFP18818.1 - 0.004 17.3 3.7 0.004 17.3 3.7 5.1 5 0 0 5 5 3 2 EGF domain SusE PF14292.6 KFP18818.1 - 2.5 8.4 19.8 7 6.9 0.7 9.6 10 0 0 10 10 10 0 SusE outer membrane protein Ank_2 PF12796.7 KFP18819.1 - 6.8e-103 337.4 22.6 2.3e-14 53.7 0.0 9.8 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP18819.1 - 7.3e-99 323.0 20.1 1.5e-10 41.4 0.0 14.1 3 3 13 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 KFP18819.1 - 1.5e-76 249.7 43.2 6.6e-06 26.3 0.1 19.4 19 0 0 19 19 19 16 Ankyrin repeat Ank_5 PF13857.6 KFP18819.1 - 6e-72 236.8 34.1 1.3e-09 38.1 0.1 12.5 4 3 10 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18819.1 - 5.3e-64 204.6 15.4 0.00021 21.5 0.0 18.6 19 0 0 19 19 19 13 Ankyrin repeat AAA_16 PF13191.6 KFP18819.1 - 0.0018 18.7 0.1 0.035 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KFP18819.1 - 0.0063 16.4 0.4 0.047 13.6 0.4 2.4 1 1 0 1 1 1 1 NACHT domain Sprouty PF05210.13 KFP18820.1 - 7.9e-27 93.7 32.4 1.8e-26 92.5 32.5 1.6 1 1 0 1 1 1 1 Sprouty protein (Spry) ATF7IP_BD PF16788.5 KFP18820.1 - 0.19 11.8 1.3 0.28 11.2 1.3 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain AAA PF00004.29 KFP18821.1 - 9.4e-85 281.7 0.0 1.4e-43 148.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFP18821.1 - 1.2e-15 57.6 0.0 3.5e-08 33.3 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFP18821.1 - 4.2e-12 46.2 0.0 8.9e-05 22.5 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KFP18821.1 - 3.1e-10 39.7 0.3 1e-09 38.1 0.3 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFP18821.1 - 4e-10 40.3 0.8 0.00013 22.4 0.2 4.1 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 KFP18821.1 - 6e-10 38.9 0.1 0.00011 21.5 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_2 PF07724.14 KFP18821.1 - 3.3e-09 37.1 0.0 0.00045 20.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP18821.1 - 3e-08 34.0 0.8 0.0096 16.2 0.1 4.5 3 2 1 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KFP18821.1 - 2.9e-07 30.1 0.7 0.0072 15.7 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFP18821.1 - 3.9e-07 30.0 0.0 0.0084 15.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KFP18821.1 - 4.4e-07 30.1 0.0 0.0049 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFP18821.1 - 1.2e-06 28.8 0.0 0.0067 16.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Parvo_NS1 PF01057.17 KFP18821.1 - 5.6e-06 25.6 0.1 0.0042 16.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KFP18821.1 - 6.1e-06 25.9 0.3 0.51 9.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.6 KFP18821.1 - 6.5e-06 26.3 0.0 0.042 14.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.15 KFP18821.1 - 7e-06 26.1 0.1 0.02 14.8 0.0 3.1 3 1 0 3 3 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KFP18821.1 - 8.2e-06 25.9 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KFP18821.1 - 1e-05 25.8 0.0 0.024 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFP18821.1 - 1.1e-05 25.0 0.1 0.092 12.2 0.0 3.1 3 1 0 3 3 2 2 P-loop containing dynein motor region TsaE PF02367.17 KFP18821.1 - 2e-05 24.6 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFP18821.1 - 2.7e-05 24.7 0.0 0.016 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KFP18821.1 - 5e-05 23.2 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFP18821.1 - 0.00017 21.0 0.0 0.088 12.1 0.0 2.4 2 0 0 2 2 2 1 KaiC CDC48_N PF02359.18 KFP18821.1 - 0.00021 21.4 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.26 KFP18821.1 - 0.00051 19.8 0.0 0.27 10.9 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 KFP18821.1 - 0.00069 19.4 0.0 0.045 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KFP18821.1 - 0.001 18.3 0.0 0.35 10.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KFP18821.1 - 0.0011 19.5 0.0 1.1 9.8 0.0 3.0 2 1 1 3 3 3 1 ABC transporter NACHT PF05729.12 KFP18821.1 - 0.0016 18.4 0.6 0.31 11.0 0.0 3.0 4 0 0 4 4 3 1 NACHT domain AAA_17 PF13207.6 KFP18821.1 - 0.0022 18.4 0.0 0.96 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFP18821.1 - 0.004 16.5 0.1 0.88 8.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 KFP18821.1 - 0.0047 16.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KFP18821.1 - 0.01 15.2 0.0 1.8 7.9 0.0 3.5 4 0 0 4 4 3 0 Bacterial TniB protein Bac_DnaA PF00308.18 KFP18821.1 - 0.028 14.3 0.0 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein CDC48_2 PF02933.17 KFP18821.1 - 0.028 14.2 0.1 0.14 11.9 0.0 2.3 2 1 1 3 3 1 0 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.6 KFP18821.1 - 0.028 14.7 0.5 0.72 10.2 0.2 2.6 2 1 1 3 3 2 0 AAA domain AAA_30 PF13604.6 KFP18821.1 - 0.029 14.1 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 KFP18821.1 - 0.035 13.5 0.1 0.86 8.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.22 KFP18821.1 - 0.04 13.1 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_6 PF12774.7 KFP18821.1 - 0.049 12.6 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 KFP18821.1 - 0.061 12.8 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 KFP18821.1 - 0.07 13.3 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 KFP18821.1 - 0.096 12.6 0.0 6.5 6.6 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KFP18821.1 - 0.13 12.0 0.1 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 KFP18821.1 - 0.15 12.2 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family ATP-synt_ab PF00006.25 KFP18821.1 - 0.15 11.7 0.1 1.5 8.4 0.1 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.9 KFP18821.1 - 0.17 11.1 0.0 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NUDIX PF00293.28 KFP18822.1 - 2.4e-19 69.7 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 KFP18822.1 - 1.5e-16 60.2 0.1 2.9e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Nudix hydrolase domain FGF PF00167.18 KFP18823.1 - 1.3e-29 102.8 0.0 1.5e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.19 KFP18823.1 - 0.00019 21.1 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Interleukin-1 / 18 Glyco_transf_15 PF01793.16 KFP18823.1 - 0.068 12.4 0.1 0.069 12.4 0.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cpn60_TCP1 PF00118.24 KFP18824.1 - 1.3e-16 60.3 0.1 2.6e-08 32.9 0.0 2.9 2 1 1 3 3 3 2 TCP-1/cpn60 chaperonin family EF-hand_1 PF00036.32 KFP18825.1 - 2e-34 114.6 17.9 5.4e-09 35.0 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP18825.1 - 7.6e-31 106.4 9.3 1.8e-15 57.1 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP18825.1 - 2.3e-27 92.5 11.2 3.3e-09 35.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KFP18825.1 - 3.1e-24 84.6 15.0 6.2e-12 45.2 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFP18825.1 - 5.1e-16 57.4 18.9 1.1e-05 24.7 0.3 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFP18825.1 - 1.3e-15 57.5 0.2 8.6e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KFP18825.1 - 6e-06 26.1 8.1 0.28 11.2 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KFP18825.1 - 0.00026 21.3 1.4 0.63 10.4 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain DUF853 PF05872.12 KFP18825.1 - 0.00068 18.4 0.3 0.65 8.5 0.0 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SurA_N_3 PF13624.6 KFP18825.1 - 0.00085 19.2 3.2 0.2 11.4 0.4 2.1 1 1 0 2 2 2 2 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KFP18825.1 - 0.0019 18.5 0.9 0.28 11.5 0.3 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP18825.1 - 0.003 17.7 0.3 0.36 11.1 0.2 2.7 1 1 1 2 2 2 1 Dockerin type I domain DUF3349 PF11829.8 KFP18825.1 - 0.013 16.3 2.3 3.8 8.4 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Sigma54_CBD PF04963.13 KFP18825.1 - 0.016 15.1 0.3 0.022 14.6 0.3 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain TerB PF05099.13 KFP18825.1 - 0.021 14.8 2.8 0.37 10.7 0.1 2.7 1 1 2 3 3 3 0 Tellurite resistance protein TerB SUB1_ProdP9 PF18213.1 KFP18825.1 - 0.024 14.5 1.3 0.036 13.9 0.3 1.8 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 KFP18825.1 - 0.049 13.5 3.5 0.67 9.8 0.5 2.6 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 KFP18825.1 - 0.055 14.4 0.1 8.5 7.3 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain PB1 PF00564.24 KFP18825.1 - 0.065 13.2 0.5 4.6 7.3 0.2 2.5 2 0 0 2 2 2 0 PB1 domain DUF4601 PF15373.6 KFP18825.1 - 0.072 12.0 0.0 0.14 11.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4601) PMBR PF09373.10 KFP18825.1 - 0.078 13.2 0.5 70 3.8 0.0 4.2 5 0 0 5 5 5 0 Pseudomurein-binding repeat Caleosin PF05042.13 KFP18825.1 - 0.099 12.6 1.7 10 6.0 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein LETM1 PF07766.13 KFP18825.1 - 0.1 12.0 2.3 0.23 10.8 1.0 2.2 1 1 1 2 2 2 0 LETM1-like protein SRI PF08236.11 KFP18825.1 - 0.35 11.1 4.2 1.3 9.2 0.0 3.0 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DUF1542 PF07564.11 KFP18825.1 - 0.56 10.4 3.7 21 5.3 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Gp-FAR-1 PF05823.12 KFP18825.1 - 1.2 9.4 6.4 1.5 9.2 0.2 2.9 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) IL15 PF02372.15 KFP18826.1 - 2.1e-14 53.7 3.1 2.5e-14 53.4 3.1 1.1 1 0 0 1 1 1 1 Interleukin 15 DUF5331 PF17265.2 KFP18826.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5331) IL15 PF02372.15 KFP18827.1 - 1.6e-29 102.6 11.7 1.9e-28 99.1 11.7 2.0 1 1 0 1 1 1 1 Interleukin 15 HEAT_UF PF18817.1 KFP18827.1 - 9.4 6.6 8.3 5.2 7.4 0.9 3.0 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 A_deamin PF02137.18 KFP18828.1 - 7.2e-90 301.8 0.5 9.9e-90 301.3 0.5 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 KFP18828.1 - 1.9e-11 44.5 0.4 9.6e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ion_trans PF00520.31 KFP18829.1 - 3.5e-32 111.6 18.4 5.4e-32 111.0 18.1 1.4 1 1 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 KFP18829.1 - 7.2e-28 96.6 1.1 1.5e-27 95.6 1.1 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 KFP18829.1 - 1.5e-13 50.2 15.5 4.4e-13 48.7 15.5 1.7 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 KFP18829.1 - 3.2e-11 43.7 0.1 5.2e-08 33.4 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP18829.1 - 1.7e-07 31.6 0.1 0.0024 18.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP18829.1 - 1e-06 28.9 0.6 1 9.8 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18829.1 - 1.2e-06 28.3 3.5 1.8 9.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFP18829.1 - 0.00027 21.3 0.4 2.5 8.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat DUF4252 PF14060.6 KFP18829.1 - 0.11 12.5 2.4 10 6.0 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) ING PF12998.7 KFP18829.1 - 0.47 11.1 5.6 16 6.1 2.3 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding BBS2_C PF14782.6 KFP18830.1 - 4.2e-05 22.5 0.5 0.0001 21.3 0.5 1.6 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KFP18830.1 - 0.00089 19.3 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region FlxA PF14282.6 KFP18830.1 - 0.012 15.6 0.5 0.029 14.4 0.5 1.5 1 0 0 1 1 1 0 FlxA-like protein ZapB PF06005.12 KFP18830.1 - 0.032 14.7 4.5 0.26 11.8 0.7 2.5 2 0 0 2 2 2 0 Cell division protein ZapB AKNA PF12443.8 KFP18830.1 - 0.041 14.5 0.3 0.1 13.3 0.3 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Jnk-SapK_ap_N PF09744.9 KFP18830.1 - 0.51 10.5 6.1 5.4 7.2 1.9 2.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Cyclin_N PF00134.23 KFP18831.1 - 1.7e-49 166.8 0.3 3.2e-49 165.9 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP18831.1 - 4e-30 104.3 0.8 1.8e-29 102.3 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNase_PH PF01138.21 KFP18832.1 - 4.8e-20 72.4 0.0 8.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFP18832.1 - 1.9e-11 43.8 0.0 5.3e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Annexin PF00191.20 KFP18833.1 - 1.4e-98 323.0 8.8 8.3e-25 86.7 0.4 4.0 4 0 0 4 4 4 4 Annexin DUF5069 PF16798.5 KFP18833.1 - 0.024 14.9 0.1 6 7.1 0.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5069) DUF2661 PF10860.8 KFP18833.1 - 0.16 12.1 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) DUF1011 PF06237.12 KFP18834.1 - 5e-40 135.8 8.7 5e-40 135.8 8.7 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1011) TNFR_c6 PF00020.18 KFP18835.1 - 4.2e-17 62.3 36.9 5.4e-11 42.7 6.3 4.2 2 1 0 3 3 3 3 TNFR/NGFR cysteine-rich region CNDH2_C PF16858.5 KFP18836.1 - 2.6e-11 43.9 0.1 3.6e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Tau95 PF09734.9 KFP18837.1 - 4.8e-34 118.2 0.1 1.4e-33 116.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PTPRCAP PF15713.5 KFP18837.1 - 0.069 13.4 3.5 0.11 12.8 3.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Glyco_transf_6 PF03414.13 KFP18838.1 - 1.5e-141 470.8 0.1 1.8e-141 470.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_tranf_2_4 PF13704.6 KFP18838.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4456 PF14644.6 KFP18839.1 - 3.7e-61 206.5 8.2 4e-61 206.3 8.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) CobU PF02283.16 KFP18840.1 - 0.0065 16.1 0.6 0.046 13.3 0.5 2.0 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4455 PF14643.6 KFP18841.1 - 1.9e-45 155.5 3.4 2e-45 155.3 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) SURF6 PF04935.12 KFP18842.1 - 1e-37 129.9 66.9 1e-37 129.9 66.9 2.1 1 1 1 2 2 2 2 Surfeit locus protein 6 Med22 PF06179.12 KFP18843.1 - 4e-27 94.5 1.9 5.4e-27 94.1 1.9 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Ribosomal_L7Ae PF01248.26 KFP18844.1 - 9e-25 86.2 0.4 4.1e-24 84.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SURF1 PF02104.15 KFP18845.1 - 4.3e-44 150.8 0.0 5.2e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 SURF1 family SURF2 PF05477.11 KFP18846.1 - 8.8e-85 284.2 5.2 1e-84 283.9 5.2 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SURF4 PF02077.15 KFP18847.1 - 2.6e-122 407.6 9.0 2.9e-122 407.4 9.0 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 KFP18847.1 - 1.9e-38 132.5 0.0 2e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DoxX PF07681.12 KFP18847.1 - 0.03 14.9 0.2 0.03 14.9 0.2 3.4 4 1 1 5 5 5 0 DoxX Pkinase PF00069.25 KFP18848.1 - 4.5e-31 108.2 0.6 5.1e-31 108.0 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18848.1 - 1.3e-24 86.9 1.0 1.4e-24 86.8 1.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP18848.1 - 3.7e-05 23.2 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP18848.1 - 0.011 15.1 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IFRD PF05004.13 KFP18849.1 - 0.019 14.1 5.6 0.34 10.0 0.2 2.2 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) GCFC PF07842.12 KFP18849.1 - 0.037 13.7 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein DUF155 PF02582.14 KFP18849.1 - 0.17 11.9 1.7 0.68 10.0 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 RNase_T PF00929.24 KFP18850.1 - 1e-21 78.2 0.0 2.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFP18850.1 - 4.5e-05 23.2 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Reprolysin_3 PF13582.6 KFP18851.1 - 8.7e-05 23.0 0.0 9.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like BetaGal_dom4_5 PF13364.6 KFP18851.1 - 0.0075 16.8 0.0 0.0077 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Reprolysin_4 PF13583.6 KFP18851.1 - 0.024 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CUB PF00431.20 KFP18852.1 - 0.0084 16.4 0.1 0.019 15.3 0.1 1.6 2 0 0 2 2 2 1 CUB domain Cg6151-P PF10233.9 KFP18853.1 - 1.6e-30 105.7 6.1 2e-30 105.4 6.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KFP18853.1 - 0.0071 16.1 2.8 0.0096 15.6 2.8 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 DUF4191 PF13829.6 KFP18853.1 - 0.055 12.8 0.1 0.055 12.8 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4282 PF14110.6 KFP18853.1 - 4.5 8.1 7.7 0.8 10.5 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) DUF3522 PF12036.8 KFP18854.1 - 2.4e-58 197.5 7.2 2.8e-58 197.3 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Oxidored_q5_N PF01059.17 KFP18854.1 - 0.12 12.5 5.3 0.26 11.4 3.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus FAM163 PF15069.6 KFP18855.1 - 4.1e-67 225.7 0.0 4.6e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.6 KFP18855.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) ECSCR PF15820.5 KFP18855.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator HCV_NS4a PF01006.20 KFP18855.1 - 3.1 7.6 5.4 3.4 7.5 3.2 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Cu2_monoox_C PF03712.15 KFP18856.1 - 5.1e-57 191.8 0.0 8.3e-57 191.1 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KFP18856.1 - 4.3e-50 169.3 0.2 6.6e-50 168.7 0.2 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KFP18856.1 - 1.3e-18 67.4 0.0 2.2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 DOMON domain GCV_T PF01571.21 KFP18857.1 - 2e-57 194.5 0.0 4e-57 193.5 0.0 1.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFP18857.1 - 6.8e-51 173.9 0.7 1.1e-50 173.2 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KFP18857.1 - 2.1e-19 69.6 2.0 4e-19 68.7 2.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KFP18857.1 - 9.7e-14 51.1 0.0 2.2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain NAD_binding_8 PF13450.6 KFP18857.1 - 0.0057 16.9 0.0 0.023 14.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFP18857.1 - 0.0065 15.7 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFP18857.1 - 0.0065 15.7 0.3 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KFP18857.1 - 0.011 15.0 0.4 0.02 14.1 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KFP18857.1 - 0.03 13.6 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFP18857.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFP18857.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KFP18857.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KFP18857.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KFP18857.1 - 0.22 10.6 0.1 0.33 10.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RhoGEF PF00621.20 KFP18858.1 - 2.3e-39 135.5 7.2 2.3e-39 135.5 7.2 2.3 3 0 0 3 3 3 1 RhoGEF domain SH3_2 PF07653.17 KFP18858.1 - 6e-28 96.3 0.4 2.9e-14 52.5 0.1 3.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFP18858.1 - 1.5e-21 75.7 0.6 3.1e-12 45.9 0.1 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP18858.1 - 1.2e-19 69.9 0.5 2.7e-11 43.2 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain CAMSAP_CH PF11971.8 KFP18858.1 - 2.8e-17 62.3 0.2 1.2e-16 60.3 0.2 2.2 1 0 0 1 1 1 1 CAMSAP CH domain SH2 PF00017.24 KFP18858.1 - 9.3e-17 60.9 0.2 3.2e-16 59.2 0.2 2.0 1 0 0 1 1 1 1 SH2 domain CH PF00307.31 KFP18858.1 - 4e-14 52.7 1.4 2.1e-13 50.4 0.0 2.7 3 0 0 3 3 3 1 Calponin homology (CH) domain C1_1 PF00130.22 KFP18858.1 - 8.3e-10 38.4 3.3 1.9e-09 37.3 3.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KFP18858.1 - 1.1e-08 35.5 1.9 1.9e-08 34.7 0.9 2.0 2 0 0 2 2 1 1 PH domain PH_10 PF15411.6 KFP18858.1 - 0.012 15.9 2.3 0.043 14.1 0.1 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain Prok-RING_1 PF14446.6 KFP18858.1 - 0.015 15.2 2.8 0.046 13.6 2.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFP18858.1 - 0.035 13.7 0.3 0.11 12.2 0.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 KFP18858.1 - 0.26 11.6 8.8 0.043 14.2 4.1 2.2 2 0 0 2 2 2 0 C1 domain SH3_3 PF08239.11 KFP18858.1 - 0.29 11.4 4.5 3.3 8.1 2.2 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain CotJB PF12652.7 KFP18858.1 - 1.3 9.3 6.9 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 CotJB protein Bromodomain PF00439.25 KFP18860.1 - 4.8e-42 141.9 5.3 2.3e-21 75.6 0.3 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFP18860.1 - 3.5e-29 100.8 0.1 3.5e-29 100.8 0.1 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Mitofilin PF09731.9 KFP18860.1 - 3.3 6.4 39.6 6.3 5.5 39.6 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.32 KFP18861.1 - 1.1e-62 206.4 19.9 5e-10 39.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP18861.1 - 4.2e-27 94.3 2.0 4.1e-05 23.8 0.1 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP18861.1 - 8.7e-15 54.3 4.7 0.0017 17.1 0.1 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 KFP18861.1 - 2.6e-12 47.0 0.1 3.1e-06 27.2 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP18861.1 - 1.5e-06 27.5 5.1 0.026 13.5 0.8 4.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP18861.1 - 1.5e-06 27.8 0.1 0.0091 15.3 0.0 3.3 1 1 3 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 KFP18861.1 - 6.5e-06 25.3 1.9 2.1 7.2 0.0 4.2 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFP18861.1 - 0.00034 19.1 0.0 0.021 13.1 0.0 2.4 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KFP18861.1 - 0.0077 15.3 0.0 0.11 11.5 0.0 2.6 2 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Hira PF07569.11 KFP18861.1 - 0.018 14.7 1.9 28 4.4 0.0 4.4 3 1 1 4 4 4 0 TUP1-like enhancer of split CDtoxinA PF03498.14 KFP18861.1 - 0.039 13.5 1.2 0.26 10.9 0.1 2.5 1 1 0 2 2 2 0 Cytolethal distending toxin A/C domain SBD PF17882.1 KFP18861.1 - 0.11 12.3 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain Nucleoporin_N PF08801.11 KFP18861.1 - 0.14 10.8 5.3 0.32 9.7 1.7 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Hormone_recep PF00104.30 KFP18862.1 - 4.1e-40 137.6 0.0 7e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.8 KFP18862.1 - 5.1e-40 136.1 23.1 7.9e-40 135.5 23.1 1.3 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.18 KFP18862.1 - 4.1e-32 110.5 16.3 6.8e-32 109.8 16.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) OLF PF02191.16 KFP18863.1 - 1.3e-89 300.1 7.5 2e-89 299.4 7.5 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFP18863.1 - 6.7e-49 164.0 8.9 2e-47 159.3 5.0 2.8 3 0 0 3 3 3 1 Neurogenesis glycoprotein Helo_like_N PF17111.5 KFP18863.1 - 0.0013 18.1 0.7 0.0013 18.1 0.7 2.5 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins zf-C4H2 PF10146.9 KFP18863.1 - 0.0036 17.6 0.9 0.0052 17.1 0.9 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein Baculo_PEP_C PF04513.12 KFP18863.1 - 0.011 15.8 2.0 0.087 12.9 1.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCP_C_terminal PF04130.13 KFP18863.1 - 0.013 15.0 2.3 0.022 14.2 2.3 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal Lipoprotein_7 PF01540.16 KFP18863.1 - 0.02 14.2 2.7 0.03 13.6 2.7 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Atg14 PF10186.9 KFP18863.1 - 0.059 12.5 8.4 0.11 11.5 8.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 KFP18863.1 - 0.065 12.8 11.5 0.44 10.1 11.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) NPV_P10 PF05531.12 KFP18863.1 - 0.07 13.6 3.4 5.8 7.5 3.4 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Xpo1 PF08389.12 KFP18863.1 - 0.084 12.9 1.8 0.1 12.6 0.4 1.7 1 1 0 1 1 1 0 Exportin 1-like protein APG17 PF04108.12 KFP18863.1 - 0.1 11.7 10.2 0.2 10.7 10.2 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Exonuc_VII_L PF02601.15 KFP18863.1 - 0.11 12.1 5.9 0.18 11.4 5.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBCC_N PF16752.5 KFP18863.1 - 0.11 13.0 12.5 1.4 9.4 12.5 2.4 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF1664 PF07889.12 KFP18863.1 - 0.19 11.8 9.3 2.3 8.3 4.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KFP18863.1 - 0.23 11.8 10.6 8.4 6.8 9.5 2.6 1 1 0 1 1 1 0 Syntaxin-like protein FUSC PF04632.12 KFP18863.1 - 0.41 9.1 3.7 0.58 8.6 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.6 KFP18863.1 - 0.47 10.6 13.2 1.3 9.3 13.2 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit MitMem_reg PF13012.6 KFP18863.1 - 0.58 10.6 3.6 3.3 8.2 3.6 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function BLOC1_2 PF10046.9 KFP18863.1 - 0.61 10.4 15.0 0.17 12.2 1.4 3.7 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm2_III-A PF03750.13 KFP18863.1 - 0.81 10.5 8.6 4.8 8.1 4.2 2.4 1 1 1 2 2 2 0 Csm2 Type III-A CLZ PF16526.5 KFP18863.1 - 0.92 9.9 14.8 2.5 8.5 4.4 3.4 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PriC PF07445.12 KFP18863.1 - 0.98 9.3 13.7 0.54 10.2 7.3 2.2 2 0 0 2 2 2 0 Primosomal replication protein priC Bacillus_HBL PF05791.11 KFP18863.1 - 1 9.2 6.9 8.6 6.2 2.9 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ABC_tran_CTD PF16326.5 KFP18863.1 - 1.4 9.2 15.5 0.56 10.5 2.7 3.7 1 1 3 4 4 4 0 ABC transporter C-terminal domain H-kinase_dim PF02895.14 KFP18863.1 - 1.5 9.3 7.4 42 4.6 7.4 2.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Laminin_II PF06009.12 KFP18863.1 - 1.6 8.8 9.1 0.71 9.9 3.7 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF2203 PF09969.9 KFP18863.1 - 3.7 8.3 10.9 3.4 8.4 0.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 KFP18863.1 - 4.2 7.5 11.4 5.7 7.1 7.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 KFP18863.1 - 5.3 7.8 13.5 24 5.7 0.6 2.7 1 1 1 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.10 KFP18863.1 - 6.1 7.0 10.8 7 6.8 0.4 3.8 2 1 1 4 4 3 0 DASH complex subunit Dad3 FapA PF03961.13 KFP18863.1 - 6.3 5.3 11.1 1.8 7.1 6.1 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A PCRF PF03462.18 KFP18863.1 - 6.9 6.5 13.1 2 8.2 5.3 2.2 1 1 1 2 2 2 0 PCRF domain Spectrin PF00435.21 KFP18863.1 - 8.4 6.9 12.6 17 6.0 0.6 2.5 1 1 1 2 2 2 0 Spectrin repeat TMPIT PF07851.13 KFP18863.1 - 9.4 5.4 11.2 2.7 7.1 6.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein Ribosomal_S2 PF00318.20 KFP18864.1 - 8.2e-44 149.4 0.5 5.6e-23 81.3 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 PIP49_C PF12260.8 KFP18865.1 - 6.8e-62 208.5 0.5 6.8e-62 208.5 0.5 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.6 KFP18865.1 - 3.1e-59 199.3 0.0 5.9e-59 198.4 0.0 1.5 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 EF-hand_1 PF00036.32 KFP18865.1 - 0.00053 19.4 0.1 0.0043 16.5 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KFP18865.1 - 0.0049 16.3 0.2 0.044 13.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFP18865.1 - 0.074 13.5 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Dockerin_1 PF00404.18 KFP18865.1 - 0.2 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain Acyltransferase PF01553.21 KFP18866.1 - 2.2e-23 82.4 0.0 2.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase EMI PF07546.13 KFP18867.1 - 1.1e-14 54.9 10.9 1.1e-14 54.9 10.9 2.4 2 1 1 3 3 2 1 EMI domain EGF_CA PF07645.15 KFP18867.1 - 4.5e-10 39.6 7.9 4.5e-10 39.6 7.9 3.1 3 1 0 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP18867.1 - 4.8e-09 36.4 6.8 4.8e-09 36.4 6.8 3.6 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KFP18867.1 - 9.6e-09 35.0 15.1 2.3e-06 27.4 0.8 3.4 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP18867.1 - 0.0053 16.9 5.2 0.0053 16.9 5.2 3.7 3 0 0 3 3 3 1 EGF domain EGF_2 PF07974.13 KFP18867.1 - 0.0061 16.9 10.1 0.0061 16.9 10.1 3.9 4 1 1 5 5 4 1 EGF-like domain DUF5320 PF17253.2 KFP18867.1 - 0.0062 17.6 0.0 0.9 10.6 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5320) EGF PF00008.27 KFP18867.1 - 0.019 15.3 35.1 0.049 13.9 5.6 4.3 4 0 0 4 4 4 0 EGF-like domain SlyX PF04102.12 KFP18867.1 - 0.077 13.6 0.2 6.5 7.5 0.0 2.2 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 KFP18867.1 - 0.094 12.8 4.5 3.8 7.7 1.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.22 KFP18867.1 - 0.14 12.4 0.1 0.49 10.6 0.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Trimer_CC PF08954.11 KFP18867.1 - 0.15 11.6 2.8 0.77 9.4 0.3 2.7 2 1 1 3 3 3 0 Trimerisation motif DUF4988 PF16378.5 KFP18867.1 - 0.23 11.1 0.0 3.4 7.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function HSBP1 PF06825.12 KFP18867.1 - 0.37 10.7 1.5 9.9 6.1 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Uds1 PF15456.6 KFP18867.1 - 0.39 10.9 2.2 1.9 8.6 0.2 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Pox_A_type_inc PF04508.12 KFP18867.1 - 4.4 7.3 9.0 0.61 10.0 1.2 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Ank_2 PF12796.7 KFP18868.1 - 8e-38 128.9 23.4 1.5e-12 47.9 1.8 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KFP18868.1 - 1.3e-30 104.4 8.3 1.7e-05 25.0 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP18868.1 - 6e-25 87.0 10.0 1.6e-10 41.0 0.2 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP18868.1 - 1.5e-23 80.3 1.6 0.00035 20.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFP18868.1 - 4.6e-22 78.1 9.0 5.7e-07 30.0 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) PUB_1 PF18486.1 KFP18868.1 - 0.069 13.0 0.5 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Sec16_C PF12931.7 KFP18869.1 - 1.1e-43 150.0 0.0 2.2e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFP18869.1 - 2.1e-06 28.3 0.0 8.1e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region CadC_C1 PF18500.1 KFP18869.1 - 0.07 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 CadC C-terminal domain 1 Exo_endo_phos PF03372.23 KFP18870.1 - 2.3e-09 37.1 0.1 3.9e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.21 KFP18871.1 - 3.5e-42 144.5 0.0 6.6e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFP18871.1 - 1.9e-36 125.3 0.0 5.2e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2695 PF10905.8 KFP18871.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Myb_DNA-binding PF00249.31 KFP18872.1 - 1.5e-56 188.4 20.0 1.8e-15 56.9 1.4 5.7 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP18872.1 - 3.6e-42 142.4 27.7 1.6e-13 50.7 0.2 5.8 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 KFP18872.1 - 1.2e-07 31.7 19.9 0.014 15.4 0.0 5.6 4 1 3 7 7 7 4 SLIDE SANT_DAMP1_like PF16282.5 KFP18872.1 - 0.0057 16.8 9.5 1 9.6 0.3 4.5 2 2 2 4 4 4 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 KFP18872.1 - 0.0083 16.3 0.3 1.3 9.3 0.1 3.0 2 1 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 KFP18872.1 - 0.069 13.2 0.0 0.83 9.8 0.0 2.9 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Kri1 PF05178.12 KFP18872.1 - 0.077 13.6 7.7 0.65 10.6 3.9 3.5 1 1 1 2 2 2 0 KRI1-like family DUF5320 PF17253.2 KFP18872.1 - 0.87 10.7 3.5 2.1 9.5 2.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) zf-DNL PF05180.12 KFP18873.1 - 6.2e-27 93.3 0.1 7.7e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger Ribosomal_S27e PF01667.17 KFP18873.1 - 0.16 11.7 0.1 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 GoLoco PF02188.17 KFP18874.1 - 2.3e-41 138.7 27.3 2.3e-11 42.9 0.7 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.6 KFP18874.1 - 8.6e-40 134.9 28.6 1.8e-09 37.8 1.1 6.0 4 2 2 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFP18874.1 - 8.1e-35 117.2 32.1 2.2e-05 24.1 0.0 8.9 10 0 0 10 10 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFP18874.1 - 7.3e-30 100.8 20.0 5.6e-06 26.0 0.3 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFP18874.1 - 3.9e-21 73.4 26.0 0.0054 16.8 0.1 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFP18874.1 - 1.6e-19 68.4 31.3 0.002 18.1 0.1 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFP18874.1 - 3.2e-19 68.2 19.6 0.00053 19.8 0.0 8.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFP18874.1 - 7.1e-07 29.5 4.8 29 5.8 0.0 7.6 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP18874.1 - 1.3e-06 28.0 9.0 0.021 14.2 1.4 3.2 2 1 1 3 3 3 3 MalT-like TPR region Rapsyn_N PF10579.9 KFP18874.1 - 9.2e-05 22.5 1.6 3 8.0 0.1 4.6 3 2 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.6 KFP18874.1 - 0.00013 22.6 12.2 0.096 13.4 0.1 6.8 3 2 1 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFP18874.1 - 0.0003 21.1 7.6 17 6.4 0.0 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP18874.1 - 0.00072 19.2 23.5 0.16 11.7 0.2 7.8 7 3 0 7 7 6 1 TPR repeat SH3BP5 PF05276.14 KFP18874.1 - 0.0056 16.5 2.9 2.4 7.9 1.0 2.6 2 0 0 2 2 2 2 SH3 domain-binding protein 5 (SH3BP5) UreE_C PF05194.12 KFP18874.1 - 0.085 13.3 1.2 6.1 7.4 0.1 3.0 2 1 1 3 3 2 0 UreE urease accessory protein, C-terminal domain ANAPC5 PF12862.7 KFP18874.1 - 0.13 12.3 1.1 29 4.8 0.0 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 KFP18874.1 - 0.46 11.0 16.0 21 5.8 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP18874.1 - 1.3 9.8 8.1 1.8e+02 3.1 0.1 6.3 7 1 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP18874.1 - 4.2 7.7 15.4 19 5.5 0.0 4.9 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 ASC PF00858.24 KFP18875.1 - 5e-23 81.8 0.0 6.1e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel RVT_1 PF00078.27 KFP18876.1 - 2.1e-21 76.5 0.0 3.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP18876.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Neur_chan_LBD PF02931.23 KFP18877.1 - 5e-43 147.0 0.0 7.3e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP18877.1 - 1e-42 146.9 0.5 1.7e-42 146.1 0.5 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3695 PF12494.8 KFP18877.1 - 0.017 15.0 0.1 8.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) DUF4396 PF14342.6 KFP18877.1 - 0.13 12.7 7.6 1.2 9.5 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Neur_chan_memb PF02932.16 KFP18878.1 - 2e-48 165.6 0.2 4.8e-48 164.3 0.2 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP18878.1 - 1.5e-37 129.2 0.1 2.5e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain COMM_domain PF07258.14 KFP18879.1 - 1e-16 60.8 1.6 1.6e-16 60.2 1.6 1.3 1 0 0 1 1 1 1 COMM domain HOIP-UBA PF16678.5 KFP18879.1 - 0.0017 18.4 0.1 0.0029 17.6 0.1 1.5 1 0 0 1 1 1 1 HOIP UBA domain pair TetR_C_23 PF17931.1 KFP18879.1 - 0.0019 18.3 0.2 0.0029 17.7 0.2 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF5344 PF17279.2 KFP18879.1 - 0.051 14.2 3.5 4.8 7.8 0.4 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Trypsin PF00089.26 KFP18880.1 - 2e-62 210.9 1.4 3.1e-62 210.3 0.1 2.0 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.18 KFP18880.1 - 1.2e-59 198.2 148.3 8.9e-11 41.8 7.2 9.4 9 1 0 9 9 9 7 Low-density lipoprotein receptor domain class A Fz PF01392.22 KFP18880.1 - 4e-44 149.8 18.3 6.5e-26 91.1 5.7 5.7 6 0 0 6 6 6 2 Fz domain SRCR_2 PF15494.6 KFP18880.1 - 1.5e-08 35.0 1.3 1.5e-08 35.0 1.3 2.9 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.6 KFP18880.1 - 3.9e-08 34.3 0.0 6.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-NF-X1 PF01422.17 KFP18881.1 - 1e-14 54.2 102.6 4.4e-06 26.6 14.7 18.0 19 0 0 19 19 19 10 NF-X1 type zinc finger Ion_trans PF00520.31 KFP18882.1 - 3.1e-33 115.0 11.0 4.3e-33 114.6 11.0 1.2 1 0 0 1 1 1 1 Ion transport protein CLZ PF16526.5 KFP18882.1 - 2.4e-27 95.1 7.5 2.8e-27 94.9 6.2 1.9 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KFP18882.1 - 2e-19 69.4 0.0 3.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP18882.1 - 0.0059 16.5 3.3 0.049 13.6 4.2 2.2 2 0 0 2 2 2 1 Ion channel GrpE PF01025.19 KFP18882.1 - 0.056 13.1 0.9 0.13 12.0 0.9 1.5 1 0 0 1 1 1 0 GrpE Prefoldin_2 PF01920.20 KFP18882.1 - 0.31 11.0 4.7 0.18 11.8 2.1 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 KFP18882.1 - 0.35 10.5 3.5 0.18 11.4 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 KFP18882.1 - 0.57 10.8 3.4 1.3 9.7 2.0 2.1 2 0 0 2 2 2 0 SlyX OmpH PF03938.14 KFP18882.1 - 3.5 7.9 9.5 13 6.2 7.8 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 KFP18882.1 - 4.7 8.0 7.6 5.4 7.8 0.1 2.8 3 0 0 3 3 3 0 Occludin homology domain Mg_trans_NIPA PF05653.14 KFP18883.1 - 7.4e-134 445.5 14.3 8.9e-134 445.2 14.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP18883.1 - 4.3e-08 33.4 4.8 4.3e-08 33.4 4.8 4.5 3 1 1 4 4 4 1 EamA-like transporter family Deltameth_res PF16020.5 KFP18883.1 - 0.11 12.3 4.7 4.2 7.3 0.1 3.4 2 1 1 3 3 3 0 Deltamethrin resistance DUF5392 PF17370.2 KFP18883.1 - 0.55 10.3 3.3 0.58 10.2 1.9 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5392) DoxX_3 PF13781.6 KFP18883.1 - 0.81 10.4 10.6 12 6.6 1.1 3.9 4 0 0 4 4 4 0 DoxX-like family Pkinase_Tyr PF07714.17 KFP18884.1 - 8.3e-95 316.9 0.1 1.2e-94 316.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP18884.1 - 3.2e-46 157.8 0.0 4.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP18884.1 - 3e-19 68.9 0.5 8.1e-19 67.5 0.2 1.9 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 KFP18884.1 - 3e-16 58.7 0.2 1.2e-15 56.8 0.1 2.1 2 0 0 2 2 2 1 SH3 domain PH PF00169.29 KFP18884.1 - 1.7e-15 57.4 0.9 1.1e-14 54.8 0.2 2.3 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KFP18884.1 - 3.2e-13 49.2 2.4 3e-12 46.1 1.9 2.5 2 0 0 2 2 2 1 BTK motif SH3_9 PF14604.6 KFP18884.1 - 7.5e-11 41.7 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP18884.1 - 2.9e-08 33.3 0.1 7.3e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP18884.1 - 0.00038 20.7 1.1 0.0076 16.5 0.5 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain hSH3 PF14603.6 KFP18884.1 - 0.0029 18.0 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_10 PF17902.1 KFP18884.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_4 PF06347.13 KFP18884.1 - 0.023 14.5 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Kinase-like PF14531.6 KFP18884.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like SLAIN PF15301.6 KFP18885.1 - 5.5e-169 563.0 42.2 6.1e-169 562.9 42.2 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family zf-3CxxC PF13695.6 KFP18886.1 - 0.92 10.0 9.8 1.3 9.5 9.8 1.3 1 0 0 1 1 1 0 Zinc-binding domain RNA_pol_Rpb1_1 PF04997.12 KFP18886.1 - 2.8 7.2 8.1 7.4 5.8 8.1 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 1 MOR2-PAG1_N PF14222.6 KFP18887.1 - 1.3e-174 582.2 4.7 2.2e-174 581.5 4.7 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFP18887.1 - 2.3e-75 253.7 5.6 2.3e-75 253.7 5.6 3.6 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFP18887.1 - 1.4e-35 122.3 15.0 3.1e-14 51.7 0.2 6.1 6 0 0 6 6 6 6 Cell morphogenesis central region OCIA PF07051.11 KFP18888.1 - 8.7e-30 102.6 0.1 1.4e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) ANAPC1 PF12859.7 KFP18888.1 - 0.019 15.5 3.1 0.026 15.1 3.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 OCIA PF07051.11 KFP18889.1 - 7.7e-18 64.3 2.0 1.2e-16 60.4 2.0 1.9 1 1 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) RELT PF12606.8 KFP18889.1 - 0.26 10.3 1.9 0.4 9.7 1.9 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF2621 PF11084.8 KFP18890.1 - 0.033 14.2 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) HCV_NS4a PF01006.20 KFP18890.1 - 0.16 11.7 0.1 0.56 10.0 0.1 1.9 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Cullin_binding PF03556.15 KFP18891.1 - 2.3e-31 108.7 0.6 3.9e-31 108.0 0.6 1.4 1 0 0 1 1 1 1 Cullin binding LRR_8 PF13855.6 KFP18892.1 - 1e-35 121.2 35.5 1.3e-14 53.7 2.4 3.5 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP18892.1 - 1e-14 54.4 27.0 7.1e-06 26.3 3.1 4.8 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP18892.1 - 4e-09 35.8 18.5 0.19 12.4 0.4 6.6 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.6 KFP18892.1 - 9.7e-09 35.3 1.8 2e-08 34.2 0.1 2.1 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP18892.1 - 2.1e-06 27.4 9.0 0.0027 17.3 2.7 2.5 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KFP18892.1 - 2.1e-05 24.2 17.2 5.9 7.2 0.7 6.8 7 0 0 7 7 7 4 Leucine Rich repeat Sarcoglycan_1 PF04790.13 KFP18893.1 - 1.6e-63 214.5 0.1 2e-63 214.2 0.1 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein Sec62 PF03839.16 KFP18893.1 - 3.4 7.1 4.3 6.8 6.1 4.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 MIEAP PF16026.5 KFP18894.1 - 1.1e-59 202.1 0.0 1.2e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein Phage_min_tail PF05939.13 KFP18894.1 - 0.056 13.8 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein UCH PF00443.29 KFP18895.1 - 2.3e-60 204.3 6.5 2.6e-60 204.1 6.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP18895.1 - 7.8e-30 104.6 10.8 1.1e-29 104.1 10.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3399 PF11879.8 KFP18895.1 - 0.45 10.9 8.5 0.94 9.8 8.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) NapB PF03892.14 KFP18895.1 - 2.9 7.9 7.9 7.6 6.6 7.9 1.7 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) IZUMO PF15005.6 KFP18896.1 - 0.089 13.3 0.5 0.23 12.0 0.3 1.8 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Fip1 PF05182.13 KFP18897.1 - 4.4e-25 86.9 2.1 4.4e-25 86.9 2.1 1.9 2 0 0 2 2 2 1 Fip1 motif PDZ PF00595.24 KFP18898.1 - 1.3e-60 201.7 1.9 5.6e-17 61.9 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP18898.1 - 1.1e-30 105.2 0.5 6.3e-08 32.3 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP18898.1 - 2.5e-15 56.6 0.0 0.0054 17.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4_2 PF13923.6 KFP18898.1 - 2.7e-06 27.1 8.4 1e-05 25.3 8.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP18898.1 - 5.2e-06 26.4 7.5 1.6e-05 24.9 7.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP18898.1 - 6.9e-06 25.8 6.9 2.3e-05 24.1 6.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP18898.1 - 1.1e-05 25.7 5.9 1.1e-05 25.7 5.9 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP18898.1 - 9.1e-05 22.3 5.1 9.1e-05 22.3 5.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP18898.1 - 0.0001 22.4 7.0 0.00043 20.4 7.0 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFP18898.1 - 0.00018 21.3 2.3 0.00018 21.3 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP18898.1 - 0.0019 18.4 3.5 0.0081 16.4 3.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain DZR PF12773.7 KFP18898.1 - 0.12 12.4 3.0 0.91 9.6 3.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF148 PF02520.17 KFP18899.1 - 0.0011 19.0 15.5 0.0011 19.0 15.5 9.2 1 1 9 10 10 10 1 Domain of unknown function DUF148 Tup_N PF08581.10 KFP18899.1 - 0.021 15.1 12.2 0.021 15.1 12.2 11.1 2 2 8 11 11 11 0 Tup N-terminal DUF424 PF04242.13 KFP18899.1 - 0.24 11.7 2.8 3.3 8.0 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF424) DUF2201 PF09967.9 KFP18899.1 - 9.9 6.3 6.7 1.4 9.0 0.1 3.1 3 0 0 3 3 3 0 VWA-like domain (DUF2201) Sushi PF00084.20 KFP18900.1 - 5e-42 142.3 26.5 8.7e-11 42.3 0.7 5.0 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) Sushi_2 PF09014.10 KFP18900.1 - 8.3e-28 96.1 1.4 8.3e-28 96.1 1.4 2.3 3 0 0 3 3 3 1 Beta-2-glycoprotein-1 fifth domain HRM PF02793.22 KFP18900.1 - 0.0028 17.9 16.2 0.57 10.5 0.1 4.5 3 1 0 4 4 4 2 Hormone receptor domain YTV PF07639.11 KFP18900.1 - 0.11 12.6 1.2 1.4 9.1 0.2 2.6 2 0 0 2 2 2 0 YTV Meleagrin PF08189.11 KFP18900.1 - 0.12 12.1 12.5 0.31 10.8 1.6 4.2 4 0 0 4 4 4 0 Meleagrin/Cygnin family Pkinase PF00069.25 KFP18901.1 - 3.9e-64 216.5 0.0 5.4e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP18901.1 - 1.1e-37 129.8 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 KFP18901.1 - 1.4e-29 102.4 0.1 2.3e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KFP18901.1 - 4.9e-18 64.8 15.9 2e-16 59.6 4.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFP18901.1 - 0.00033 21.3 0.6 0.0009 19.9 0.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFP18901.1 - 0.044 12.7 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KFP18901.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP18901.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PMP22_Claudin PF00822.20 KFP18902.1 - 1.1e-21 77.4 3.9 2.8e-21 76.1 3.9 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP18902.1 - 2.9e-21 76.1 3.7 4.3e-21 75.6 3.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF716 PF04819.12 KFP18902.1 - 0.022 14.4 0.2 0.041 13.5 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF716) Claudin_3 PF06653.11 KFP18902.1 - 0.79 9.7 10.0 1.7 8.5 10.0 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DHHC PF01529.20 KFP18902.1 - 0.86 9.7 7.3 0.12 12.4 2.2 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase MFS_1 PF07690.16 KFP18902.1 - 2.3 7.0 14.8 13 4.6 14.4 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily Tetraspanin PF00335.20 KFP18902.1 - 3 7.5 8.0 2.9 7.5 1.9 2.4 2 1 0 2 2 2 0 Tetraspanin family DUF4199 PF13858.6 KFP18902.1 - 3.3 8.1 10.5 4.8 7.5 10.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) PMP22_Claudin PF00822.20 KFP18903.1 - 1.4e-24 86.8 0.0 2.4e-24 86.1 0.0 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP18903.1 - 3.6e-10 39.9 0.0 5.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.6 KFP18903.1 - 0.0031 16.4 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2269 PF10027.9 KFP18903.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF4199 PF13858.6 KFP18903.1 - 0.025 15.0 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Claudin_2 PF13903.6 KFP18904.1 - 5.8e-39 133.9 4.5 7.1e-39 133.6 4.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP18904.1 - 7.5e-16 58.4 6.6 7.4e-09 35.7 4.3 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family HisKA_7TM PF16927.5 KFP18904.1 - 0.017 15.2 2.8 0.027 14.5 1.0 1.8 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase DUF981 PF06168.11 KFP18904.1 - 0.026 14.4 2.2 0.13 12.2 1.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF2207 PF09972.9 KFP18904.1 - 0.15 10.8 1.7 0.16 10.7 0.8 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF805 PF05656.14 KFP18904.1 - 0.26 11.7 3.3 0.13 12.6 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DuoxA PF10204.9 KFP18904.1 - 0.28 10.2 5.6 0.08 11.9 2.4 1.6 2 0 0 2 2 2 0 Dual oxidase maturation factor UNC-50 PF05216.13 KFP18904.1 - 1.1 8.7 7.9 0.058 12.9 2.8 1.4 2 0 0 2 2 2 0 UNC-50 family AAA_12 PF13087.6 KFP18905.1 - 1.3e-34 119.6 0.0 2.7e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP18905.1 - 2.1e-22 80.2 11.9 2.2e-12 47.3 0.1 3.7 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.6 KFP18905.1 - 5.1e-10 39.9 0.0 6.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP18905.1 - 8.4e-09 35.4 0.0 3.8e-08 33.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 KFP18905.1 - 7.3e-08 32.1 0.6 2e-07 30.8 0.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ResIII PF04851.15 KFP18905.1 - 1.7e-05 24.9 0.0 4.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFP18905.1 - 2.4e-05 23.9 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 KFP18905.1 - 0.00011 21.9 0.0 0.00011 21.9 0.0 2.8 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain PAM2 PF07145.15 KFP18905.1 - 0.00022 20.7 0.1 0.00092 18.7 0.1 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region zf_CCCH_4 PF18345.1 KFP18905.1 - 0.0011 18.9 1.2 0.0028 17.6 1.2 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFP18905.1 - 0.0055 16.5 0.3 0.014 15.2 0.3 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_7 PF12775.7 KFP18905.1 - 0.024 14.2 0.0 0.071 12.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 KFP18905.1 - 0.038 13.8 0.1 0.24 11.2 0.0 2.5 2 0 0 2 2 2 0 Helicase AAA_14 PF13173.6 KFP18905.1 - 0.04 14.0 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP18905.1 - 0.045 14.0 0.0 0.18 12.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KFP18905.1 - 0.071 12.9 0.3 0.31 10.8 0.0 2.1 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_16 PF13191.6 KFP18905.1 - 0.086 13.2 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.14 KFP18905.1 - 0.17 11.9 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PCI PF01399.27 KFP18906.1 - 2.2e-23 82.8 1.6 9.8e-23 80.7 0.0 2.8 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFP18906.1 - 1.9e-15 56.6 8.4 4.4e-15 55.5 8.4 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Hydrophob_seed PF14547.6 KFP18906.1 - 0.084 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Hydrophobic seed protein Tubulin_C PF03953.17 KFP18906.1 - 0.16 12.1 0.7 0.7 10.1 0.1 2.4 2 1 1 3 3 3 0 Tubulin C-terminal domain IP_trans PF02121.18 KFP18907.1 - 1.2e-95 319.8 3.5 1.4e-95 319.6 3.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein NUC205 PF08168.11 KFP18908.1 - 8.8e-08 31.5 0.1 2.2e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 NUC205 domain HisG_C PF08029.11 KFP18908.1 - 0.014 15.5 0.0 0.6 10.3 0.0 2.5 2 0 0 2 2 2 0 HisG, C-terminal domain UTP15_C PF09384.10 KFP18908.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal PHD PF00628.29 KFP18909.1 - 4.4e-18 64.9 28.7 1.9e-09 37.3 7.1 3.0 2 0 0 2 2 2 2 PHD-finger DDT PF02791.17 KFP18909.1 - 4.4e-17 62.1 0.3 9.2e-17 61.1 0.3 1.6 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KFP18909.1 - 8.4e-10 39.0 1.5 8.4e-10 39.0 1.5 6.1 6 1 0 6 6 6 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 KFP18909.1 - 0.00022 20.7 0.0 0.00065 19.2 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 C1_1 PF00130.22 KFP18909.1 - 1.5 8.7 14.3 4.5 7.2 1.2 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Arc_PepC_II PF06847.11 KFP18909.1 - 7.2 7.2 6.3 1.9 9.0 0.4 3.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II RVT_1 PF00078.27 KFP18910.1 - 1.4e-18 67.2 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP18910.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Neur_chan_LBD PF02931.23 KFP18911.1 - 7.3e-52 175.9 0.1 1.1e-51 175.3 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP18911.1 - 1.7e-37 129.8 6.4 8.1e-33 114.5 2.5 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Myelin_PLP PF01275.19 KFP18915.1 - 8.8e-92 307.3 23.7 1e-91 307.1 23.7 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF2701 PF10857.8 KFP18915.1 - 0.11 12.6 2.1 0.33 11.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2701) WD40 PF00400.32 KFP18916.1 - 1.3e-31 108.1 38.3 5.8e-07 30.1 0.2 10.6 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP18916.1 - 5.4e-23 81.1 0.0 0.00024 21.4 0.0 6.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP18916.1 - 7.7e-05 22.7 0.0 0.25 11.2 0.0 4.4 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP18916.1 - 0.012 14.3 8.9 0.48 9.0 0.0 5.3 6 1 1 7 7 7 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP18916.1 - 0.074 12.0 0.2 5.2 5.9 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 KFP18917.1 - 1.4e-30 105.6 0.7 4.2e-13 49.7 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP18917.1 - 5.9e-29 100.1 2.5 1.5e-10 41.3 0.1 5.1 3 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP18917.1 - 9.8e-25 85.9 9.8 2.6e-06 27.6 0.2 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KFP18917.1 - 1.2e-24 83.7 7.0 3.3e-05 23.9 0.1 7.5 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KFP18917.1 - 2.7e-20 72.1 4.5 1.4e-06 28.4 0.1 5.4 2 2 4 6 6 6 3 Ankyrin repeats (many copies) SOCS_box PF07525.16 KFP18917.1 - 3.3e-10 40.1 7.5 5.9e-10 39.3 6.4 2.0 2 0 0 2 2 2 1 SOCS box SPC22 PF04573.12 KFP18918.1 - 2.1e-42 144.5 0.1 4.7e-42 143.4 0.1 1.5 1 1 0 1 1 1 1 Signal peptidase subunit CBM_3 PF00942.18 KFP18918.1 - 0.068 13.6 0.0 0.09 13.2 0.0 1.2 1 0 0 1 1 1 0 Cellulose binding domain PDGF PF00341.17 KFP18919.1 - 6.5e-23 80.8 7.2 6.5e-23 80.8 7.2 3.2 3 0 0 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.14 KFP18919.1 - 6.1e-09 35.7 61.8 0.00052 20.3 5.0 9.0 8 0 0 8 8 8 6 CXCXC repeat zf-GRF PF06839.12 KFP18921.1 - 2.5e-33 113.9 12.7 3.1e-18 65.6 4.6 4.5 5 0 0 5 5 5 2 GRF zinc finger H2TH PF06831.14 KFP18921.1 - 3.4e-11 43.0 0.0 6.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KFP18921.1 - 0.00011 22.8 0.0 0.00032 21.3 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-RanBP PF00641.18 KFP18921.1 - 0.00014 21.0 1.4 0.00014 21.0 1.4 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others MIT_LIKE_ACTX PF17556.2 KFP18921.1 - 0.26 11.9 0.2 0.26 11.9 0.2 3.7 3 1 0 4 4 4 0 MIT-like atracotoxin family zf-FPG_IleRS PF06827.14 KFP18921.1 - 0.79 9.7 12.3 0.16 11.8 3.9 3.8 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Asparaginase_2 PF01112.18 KFP18922.1 - 9.5e-65 218.6 0.0 1.3e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Asparaginase DUF4462 PF14692.6 KFP18924.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Ten_N PF06484.12 KFP18925.1 - 1e-35 124.3 4.9 1.2e-35 124.2 4.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region dCMP_cyt_deam_1 PF00383.23 KFP18926.1 - 1.5e-28 98.6 0.2 2.4e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFP18926.1 - 9.5e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KFP18926.1 - 0.02 15.0 0.2 0.046 13.8 0.1 1.7 2 0 0 2 2 2 0 APOBEC3 APOBEC4_like PF18774.1 KFP18926.1 - 0.032 14.2 0.4 0.096 12.6 0.1 1.8 1 1 1 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase WW PF00397.26 KFP18928.1 - 9e-08 32.1 0.2 1.9e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 WW domain CENP-B_dimeris PF09026.10 KFP18928.1 - 3.4 8.1 0.0 3.4 8.1 0.0 3.5 2 1 1 3 3 3 0 Centromere protein B dimerisation domain PMP22_Claudin PF00822.20 KFP18929.1 - 1.7e-24 86.6 0.7 2.1e-24 86.3 0.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP18929.1 - 5.5e-07 29.5 5.0 6.8e-06 26.0 5.0 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction XTBD PF11952.8 KFP18930.1 - 0.00031 20.4 0.1 0.057 13.2 0.1 2.6 2 0 0 2 2 2 2 XRN-Two Binding Domain, XTBD Ferlin_C PF16165.5 KFP18930.1 - 3.4 7.6 7.6 7.1 6.6 7.6 1.6 1 0 0 1 1 1 0 Ferlin C-terminus ING PF12998.7 KFP18931.1 - 5.1e-12 46.3 3.8 5.1e-12 46.3 3.8 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP18931.1 - 2.8e-06 27.1 7.6 2.8e-06 27.1 7.6 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFP18931.1 - 0.0026 17.3 2.8 0.007 15.9 2.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.11 KFP18931.1 - 0.011 16.0 4.9 0.15 12.4 2.6 2.6 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.6 KFP18931.1 - 0.23 11.7 6.6 0.062 13.6 2.8 2.1 2 1 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_S46 PF10459.9 KFP18931.1 - 2.9 6.4 5.8 3.6 6.1 5.8 1.1 1 0 0 1 1 1 0 Peptidase S46 RWD PF05773.22 KFP18933.1 - 4.8e-13 49.4 0.0 1.3e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 RWD domain Inhibitor_I71 PF12628.7 KFP18933.1 - 0.013 15.3 0.3 0.018 14.9 0.3 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Foie-gras_1 PF11817.8 KFP18934.1 - 1.8e-77 260.5 0.7 3.1e-77 259.7 0.7 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 KFP18934.1 - 4.4e-23 81.0 0.0 2.6e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Gryzun PF07919.12 KFP18934.1 - 3.8e-11 42.5 0.1 9.4e-09 34.6 0.3 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Prefoldin PF02996.17 KFP18934.1 - 0.058 13.3 0.1 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit Stork_head PF10264.9 KFP18935.1 - 7.7e-30 102.9 0.1 1.5e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Phosphodiest PF01663.22 KFP18936.1 - 1e-77 262.1 0.6 1.2e-77 261.9 0.6 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KFP18936.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFP18936.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KFP18936.1 - 0.0043 17.2 0.1 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 PglZ domain DUF229 PF02995.17 KFP18936.1 - 0.026 13.1 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) IRF PF00605.17 KFP18937.1 - 4e-42 142.8 1.0 7.5e-42 141.9 1.0 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Heme_oxygenase PF01126.20 KFP18937.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase CENP-U PF13097.6 KFP18939.1 - 2.1e-55 187.5 11.5 2.1e-55 187.5 11.5 2.0 2 0 0 2 2 2 1 CENP-A nucleosome associated complex (NAC) subunit Mt_ATP-synt_B PF05405.14 KFP18939.1 - 0.017 14.7 2.7 0.017 14.7 2.7 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mod_r PF07200.13 KFP18939.1 - 0.41 10.7 15.8 1.5 9.0 10.3 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tex_N PF09371.10 KFP18939.1 - 0.48 10.1 10.0 0.41 10.3 8.2 1.8 1 1 1 2 2 2 0 Tex-like protein N-terminal domain I_LWEQ PF01608.17 KFP18939.1 - 0.64 10.2 10.2 0.087 13.1 5.0 2.2 2 0 0 2 2 2 0 I/LWEQ domain She9_MDM33 PF05546.11 KFP18939.1 - 0.65 9.8 8.9 0.14 11.9 1.5 2.3 2 0 0 2 2 2 0 She9 / Mdm33 family GAS PF13851.6 KFP18939.1 - 0.74 9.1 17.1 0.05 12.9 9.8 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Mito_carr PF00153.27 KFP18941.1 - 5.3e-58 193.0 4.3 4.3e-24 84.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 KFP18941.1 - 0.029 13.6 0.1 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Fuseless Nexin_C PF08628.12 KFP18943.1 - 3.1e-28 98.6 0.3 2.1e-27 95.9 0.2 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PXA PF02194.15 KFP18943.1 - 4.3e-24 85.5 7.9 2.6e-23 82.9 3.0 3.8 2 2 0 2 2 2 1 PXA domain RGS PF00615.19 KFP18943.1 - 9.9e-21 74.2 0.8 9.9e-21 74.2 0.8 3.0 3 0 0 3 3 3 1 Regulator of G protein signaling domain PX PF00787.24 KFP18943.1 - 2.8e-18 66.0 1.1 1.4e-17 63.6 0.2 2.8 2 0 0 2 2 2 1 PX domain Isy1 PF06246.12 KFP18943.1 - 0.0091 15.6 0.2 0.0091 15.6 0.2 2.7 3 0 0 3 3 3 1 Isy1-like splicing family FAST_2 PF08368.12 KFP18943.1 - 0.2 12.5 2.1 3.7 8.4 0.1 3.6 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 DUF4199 PF13858.6 KFP18943.1 - 0.34 11.3 1.1 0.87 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) GAS PF13851.6 KFP18943.1 - 6.4 6.1 15.7 0.02 14.3 3.8 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Sel1 PF08238.12 KFP18944.1 - 5.4e-28 96.8 19.3 2.5e-06 28.0 0.0 5.7 6 0 0 6 6 6 5 Sel1 repeat TPR_6 PF13174.6 KFP18944.1 - 0.00024 21.5 9.5 2.2 9.1 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TENA_THI-4 PF03070.16 KFP18944.1 - 0.003 17.4 0.1 0.072 12.9 0.0 2.1 2 0 0 2 2 2 1 TENA/THI-4/PQQC family TPR_8 PF13181.6 KFP18944.1 - 0.24 11.7 14.3 0.44 10.9 0.2 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C78 PF07910.13 KFP18945.1 - 1.4e-52 178.2 0.1 2.3e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 DUF4586 PF15239.6 KFP18946.1 - 2.6e-114 382.5 10.7 3e-114 382.3 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) DUF4749 PF15936.5 KFP18947.1 - 7e-27 94.4 0.6 1.2e-26 93.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ PF00595.24 KFP18947.1 - 9.8e-17 61.1 0.0 2.3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KFP18947.1 - 1e-13 51.3 3.4 1.7e-13 50.6 3.4 1.4 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KFP18947.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP18947.1 - 0.00074 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Lar_restr_allev PF14354.6 KFP18947.1 - 0.28 11.6 2.1 0.62 10.5 2.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar SH3_1 PF00018.28 KFP18948.1 - 6.5e-29 99.3 0.1 3.4e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Sorb PF02208.16 KFP18948.1 - 7.6e-26 89.7 4.3 1.4e-22 79.3 0.3 2.7 2 0 0 2 2 2 2 Sorbin homologous domain SH3_9 PF14604.6 KFP18948.1 - 5.7e-23 80.5 0.1 4.5e-11 42.4 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KFP18948.1 - 1.1e-20 73.0 0.2 9.3e-14 50.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain LRR_8 PF13855.6 KFP18951.1 - 1.7e-77 255.1 101.6 1e-12 47.6 2.5 11.6 3 3 9 14 14 14 14 Leucine rich repeat LRR_4 PF12799.7 KFP18951.1 - 2.7e-32 110.2 107.5 0.00027 21.2 5.1 13.4 6 3 7 15 15 15 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP18951.1 - 2.7e-25 88.8 28.6 3.4e-09 36.7 2.5 6.0 2 1 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) Tlr3_TMD PF17968.1 KFP18951.1 - 1.4e-18 66.7 3.9 3.5e-18 65.5 3.9 1.8 1 0 0 1 1 1 1 Toll-like receptor 3 trans-membrane domain TIR PF01582.20 KFP18951.1 - 6.3e-10 39.1 2.8 1e-09 38.5 2.8 1.3 1 0 0 1 1 1 1 TIR domain LRR_9 PF14580.6 KFP18951.1 - 1.2e-08 34.7 37.3 0.0029 17.1 0.7 7.1 1 1 5 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 KFP18951.1 - 6e-08 32.2 92.6 0.45 11.2 0.4 20.4 22 1 0 22 22 22 3 Leucine Rich Repeat TIR_2 PF13676.6 KFP18951.1 - 4.6e-07 30.5 0.5 1.6e-06 28.7 0.2 2.0 2 0 0 2 2 2 1 TIR domain LRRNT PF01462.18 KFP18951.1 - 0.0027 17.3 0.0 0.014 15.0 0.0 2.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF3719 PF12516.8 KFP18952.1 - 7.4e-24 83.2 0.0 3.2e-23 81.2 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) p450 PF00067.22 KFP18953.1 - 1.1e-124 416.7 0.0 1.3e-124 416.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peripla_BP_1 PF00532.21 KFP18953.1 - 0.048 13.1 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Trypsin PF00089.26 KFP18954.1 - 9.1e-72 241.4 0.0 1.3e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFP18954.1 - 6.2e-28 96.6 35.9 1.6e-08 34.4 0.8 4.8 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.6 KFP18954.1 - 1.2e-15 57.1 23.2 9.1e-06 25.5 0.5 5.5 5 1 0 5 5 5 4 PAN domain Trypsin_2 PF13365.6 KFP18954.1 - 5.4e-06 27.4 0.0 1.1e-05 26.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP18954.1 - 0.00053 20.4 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) 7tm_1 PF00001.21 KFP18958.1 - 4.3e-42 144.2 21.6 5.2e-42 144.0 21.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP18958.1 - 2.1e-06 27.6 24.6 6.9e-06 25.9 24.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP18958.1 - 0.0078 16.0 13.7 0.28 10.9 13.7 2.1 1 1 0 1 1 1 1 Olfactory receptor DUF4233 PF14017.6 KFP18958.1 - 0.56 10.6 14.7 0.19 12.1 1.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) Cadherin PF00028.17 KFP18959.1 - 0 1697.5 98.6 1.2e-23 83.3 0.3 34.3 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.24 KFP18959.1 - 2.9e-28 99.0 0.2 2.7e-27 95.8 0.3 2.8 2 0 0 2 2 2 1 Laminin G domain Cadherin_3 PF16184.5 KFP18959.1 - 8.2e-26 90.2 61.2 0.0077 16.2 0.1 20.5 22 0 0 22 22 22 7 Cadherin-like Laminin_G_1 PF00054.23 KFP18959.1 - 8e-19 68.2 0.1 4.8e-18 65.6 0.0 2.6 2 0 0 2 2 1 1 Laminin G domain Cadherin_2 PF08266.12 KFP18959.1 - 9.3e-19 67.1 5.3 3.4 7.6 0.0 18.1 21 0 0 21 21 21 1 Cadherin-like RET_CLD1 PF17756.1 KFP18959.1 - 3.7e-13 49.9 1.5 2.9 8.2 0.1 11.4 10 2 2 12 12 12 3 RET Cadherin like domain 1 EGF PF00008.27 KFP18959.1 - 2e-12 47.1 59.8 6.9e-05 23.1 9.9 4.8 5 0 0 5 5 4 3 EGF-like domain Cadherin_pro PF08758.11 KFP18959.1 - 2e-09 37.5 2.5 5 7.4 0.0 12.5 14 0 0 14 14 14 1 Cadherin prodomain like EGF_CA PF07645.15 KFP18959.1 - 9.5e-06 25.7 10.4 9.5e-06 25.7 10.4 4.5 3 1 1 4 4 4 1 Calcium-binding EGF domain Y_Y_Y PF07495.13 KFP18959.1 - 1.9e-05 24.5 3.5 49 4.0 0.0 10.7 11 1 0 11 11 11 0 Y_Y_Y domain Cadherin_4 PF17803.1 KFP18959.1 - 0.00017 22.2 108.7 0.084 13.5 0.9 19.3 21 0 0 21 21 21 7 Bacterial cadherin-like domain Laminin_G_3 PF13385.6 KFP18959.1 - 0.015 15.5 0.1 0.11 12.7 0.1 2.5 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFP18959.1 - 0.13 12.9 47.3 0.089 13.5 5.5 5.0 5 0 0 5 5 5 0 Human growth factor-like EGF MBF2 PF15868.5 KFP18959.1 - 2.7 8.6 5.7 33 5.1 0.0 6.1 8 0 0 8 8 4 0 Transcription activator MBF2 FRG1 PF06229.12 KFP18964.1 - 5.7e-81 270.8 1.4 7.3e-81 270.5 1.4 1.1 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KFP18964.1 - 2.6e-08 34.1 0.0 1.2e-07 32.0 0.0 2.0 3 0 0 3 3 3 1 Fascin domain DUF569 PF04601.13 KFP18964.1 - 0.00016 21.4 0.3 0.0016 18.1 0.0 2.7 1 1 0 2 2 2 1 Domain of unknown function (DUF569) CBAH PF02275.18 KFP18965.1 - 5e-38 131.5 0.6 5e-36 125.0 0.6 2.2 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 KFP18965.1 - 9.5e-22 77.1 0.3 3.1e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAT PF03417.16 KFP18965.1 - 0.038 13.7 0.0 0.098 12.3 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TFIIE_alpha PF02002.17 KFP18966.1 - 2.9e-29 101.0 1.5 2.9e-29 101.0 1.5 1.6 2 0 0 2 2 2 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KFP18966.1 - 1.4e-19 70.2 8.7 1.1e-18 67.3 8.7 2.3 1 1 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KFP18966.1 - 2.9e-07 29.9 0.8 6.5e-07 28.8 0.8 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFP18966.1 - 0.034 14.1 0.4 0.066 13.1 0.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.13 KFP18966.1 - 0.5 10.4 4.7 3.7 7.7 4.7 2.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like PCM1_C PF15717.5 KFP18967.1 - 3e-270 898.3 50.1 3e-270 898.3 50.1 7.1 4 3 1 6 6 6 1 Pericentriolar material 1 C terminus Fibrinogen_C PF00147.18 KFP18968.1 - 1.9e-78 263.3 13.7 2.3e-78 263.0 13.7 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF3805 PF12712.7 KFP18968.1 - 8.2 6.6 9.1 0.47 10.6 1.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3805) Ig_3 PF13927.6 KFP18972.1 - 1.8e-17 63.7 0.7 1.5e-08 35.1 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP18972.1 - 3.9e-14 52.6 0.3 1.4e-05 25.1 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP18972.1 - 3e-13 49.7 0.1 9.8e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP18972.1 - 2.6e-10 40.5 2.2 0.0011 19.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KFP18972.1 - 0.01 15.4 0.1 0.56 9.8 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain V-set PF07686.17 KFP18972.1 - 0.012 15.8 1.0 5.4 7.2 0.1 3.7 2 2 1 3 3 3 0 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP18972.1 - 0.037 14.1 0.1 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain AA_permease_2 PF13520.6 KFP18974.1 - 1.8e-51 175.4 27.4 1.8e-51 175.4 27.4 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KFP18974.1 - 2.5e-35 122.0 25.8 2.5e-35 122.0 25.8 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP18974.1 - 3.5e-24 84.6 6.5 3.5e-24 84.6 6.5 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease MAP17 PF15807.5 KFP18974.1 - 0.086 13.1 1.4 0.2 11.9 1.4 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Myotub-related PF06602.14 KFP18977.1 - 7.8e-146 485.5 0.3 1.1e-145 485.1 0.3 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP18977.1 - 0.00081 19.2 0.1 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.20 KFP18977.1 - 0.0012 18.6 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP18977.1 - 0.0086 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP18977.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.8 KFP18977.1 - 0.095 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Mod_r PF07200.13 KFP18979.1 - 4.4e-39 133.9 15.4 5.8e-39 133.5 15.4 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.13 KFP18979.1 - 0.00055 19.8 4.5 0.004 17.0 0.6 2.8 3 0 0 3 3 3 1 UEV domain DUF3535 PF12054.8 KFP18979.1 - 0.0041 16.4 1.4 0.007 15.7 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Tropomyosin_1 PF12718.7 KFP18979.1 - 3.2 7.9 13.7 0.66 10.1 9.8 1.7 1 1 0 1 1 1 0 Tropomyosin like UPF0242 PF06785.11 KFP18979.1 - 6.5 6.8 14.0 14 5.8 14.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CAF1 PF04857.20 KFP18980.1 - 1.2e-22 80.5 0.6 1.7e-11 43.8 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease DHHC PF01529.20 KFP18981.1 - 1.3e-35 122.4 14.2 1.3e-35 122.4 14.2 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 KFP18981.1 - 1.3 9.2 6.8 2.4 8.3 6.8 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger EF-hand_8 PF13833.6 KFP18982.1 - 1.7e-16 59.8 7.5 1.5e-07 31.2 0.0 6.0 6 1 0 6 6 6 2 EF-hand domain pair EF-hand_7 PF13499.6 KFP18982.1 - 4.3e-13 49.5 15.3 1.1e-05 25.7 0.1 5.6 4 3 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KFP18982.1 - 2.9e-11 42.3 9.3 0.00027 20.6 0.5 6.3 8 0 0 8 8 8 2 EF-hand domain EF-hand_1 PF00036.32 KFP18982.1 - 1.4e-09 36.8 20.0 0.0001 21.6 0.7 6.9 8 0 0 8 8 8 2 EF hand EF-hand_4 PF12763.7 KFP18982.1 - 0.0051 16.7 0.7 0.053 13.5 0.1 2.8 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFP18982.1 - 0.11 12.0 11.7 2.9 7.6 0.2 5.1 6 0 0 6 6 6 0 EF hand DUF4734 PF15881.5 KFP18982.1 - 0.21 11.8 1.6 22 5.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) FGF PF00167.18 KFP18985.1 - 4.1e-33 114.2 0.1 4.6e-33 114.0 0.1 1.0 1 0 0 1 1 1 1 Fibroblast growth factor OST3_OST6 PF04756.13 KFP18987.1 - 1.7e-93 313.2 0.1 1.9e-93 313.1 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KFP18987.1 - 2.1e-05 24.5 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Gram_pos_anchor PF00746.21 KFP18987.1 - 0.045 13.7 0.4 0.079 12.9 0.4 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif YhhN PF07947.14 KFP18987.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 YhhN family Sarcoglycan_1 PF04790.13 KFP18989.1 - 2.6e-86 289.2 0.0 3e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFP18989.1 - 1.7e-05 24.7 0.1 0.0025 17.7 0.0 2.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) ORF_2_N PF18492.1 KFP18989.1 - 0.16 12.2 0.1 8.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Open reading frame 2 N-terminal domain START PF01852.19 KFP18992.1 - 1.1e-49 168.7 0.1 2.4e-49 167.6 0.1 1.6 1 0 0 1 1 1 1 START domain RhoGAP PF00620.27 KFP18992.1 - 1.2e-41 142.0 0.7 5.5e-41 139.9 0.9 1.9 2 0 0 2 2 2 1 RhoGAP domain Methyltransf_11 PF08241.12 KFP18993.1 - 2.1e-14 54.0 0.0 4.3e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP18993.1 - 8.6e-14 52.0 0.0 2.2e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP18993.1 - 2.5e-07 30.6 0.1 5.9e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP18993.1 - 4.9e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP18993.1 - 6.8e-07 30.0 0.1 2.9e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP18993.1 - 1e-05 25.0 0.0 4.4e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KFP18993.1 - 1.1e-05 25.5 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KFP18993.1 - 9.7e-05 21.8 0.1 0.0035 16.7 0.1 2.6 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFP18993.1 - 0.0092 14.9 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) DUF4518 PF15008.6 KFP18993.1 - 0.07 12.3 0.3 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) LON_substr_bdg PF02190.16 KFP18994.1 - 3.6e-27 95.6 0.0 7e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFP18994.1 - 2.3e-09 36.9 14.3 5.1e-09 35.8 14.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP18994.1 - 3.5e-09 36.4 8.3 8.4e-09 35.2 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP18994.1 - 2e-07 30.9 8.6 2e-07 30.9 8.6 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP18994.1 - 2.5e-07 30.4 12.4 6.6e-07 29.1 12.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP18994.1 - 6e-07 29.7 13.1 1.6e-06 28.3 13.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP18994.1 - 8e-06 25.7 12.2 1.7e-05 24.7 12.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP18994.1 - 1.9e-05 24.5 9.9 3.7e-05 23.5 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP18994.1 - 5.8e-05 23.2 11.9 0.00019 21.5 11.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFP18994.1 - 7.2e-05 22.9 6.5 0.00017 21.7 6.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 TPR_2 PF07719.17 KFP18994.1 - 0.0001 22.1 0.0 0.041 14.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat U-box PF04564.15 KFP18994.1 - 0.0013 18.9 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain NARP1 PF12569.8 KFP18994.1 - 0.012 14.6 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-rbx1 PF12678.7 KFP18994.1 - 0.014 15.6 9.2 0.034 14.4 9.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_1 PF00515.28 KFP18994.1 - 0.016 15.0 0.1 9.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KFP18994.1 - 0.028 14.2 5.0 0.084 12.7 5.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_11 PF13414.6 KFP18994.1 - 0.03 14.0 0.0 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 TPR repeat zf-RING_6 PF14835.6 KFP18994.1 - 0.074 12.9 6.6 0.18 11.7 6.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 KFP18994.1 - 4.4 7.2 7.0 1.8 8.5 4.2 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) SAICAR_synt PF01259.18 KFP18995.1 - 7.9e-55 186.2 0.1 1.1e-54 185.7 0.1 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 KFP18995.1 - 2.7e-39 134.1 0.0 4.6e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 AIR carboxylase Myb_DNA-bind_4 PF13837.6 KFP18996.1 - 4.9e-19 68.5 1.6 6.1e-19 68.2 1.6 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFP18996.1 - 0.0015 18.7 1.8 0.0027 17.8 1.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP18996.1 - 0.015 15.5 1.9 0.045 14.0 1.9 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFP18996.1 - 0.023 14.7 3.8 0.13 12.4 3.8 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KFP18996.1 - 0.11 13.5 1.1 0.16 13.0 1.1 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain GATase_6 PF13522.6 KFP18997.1 - 5.5e-15 55.8 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFP18997.1 - 7.5e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFP18997.1 - 1.8e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFP18997.1 - 1.3e-06 27.5 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFP18997.1 - 0.0059 15.4 0.0 0.0093 14.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UPRTase PF14681.6 KFP18997.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KFP18997.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase AMP-binding PF00501.28 KFP18998.1 - 8.4e-46 156.4 0.0 1.4e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 KFP18998.1 - 1.4e-35 120.9 0.0 1.1e-06 28.9 0.1 9.4 9 0 0 9 9 9 6 PQQ-like domain PQQ PF01011.21 KFP18998.1 - 1.4e-21 75.4 7.3 0.0047 16.8 0.0 8.6 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 KFP18998.1 - 6.2e-17 62.0 0.0 3.6e-10 39.8 0.0 3.5 2 1 1 3 3 3 2 PQQ-like domain AMP-binding_C PF13193.6 KFP18998.1 - 1.6e-07 32.2 0.1 3.9e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ANAPC4_WD40 PF12894.7 KFP18998.1 - 0.0049 17.1 1.3 2.8 8.3 0.0 4.8 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Meleagrin PF08189.11 KFP18998.1 - 0.02 14.6 0.6 0.11 12.3 0.6 2.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family PP-binding PF00550.25 KFP18998.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Sec3_C PF09763.9 KFP19000.1 - 1.7e-181 605.2 28.0 2.1e-181 604.9 28.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KFP19000.1 - 1.2e-26 92.7 1.8 4.4e-26 90.8 1.8 2.0 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FlaC_arch PF05377.11 KFP19000.1 - 0.06 13.8 5.2 0.27 11.7 2.3 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TEX13 PF15186.6 KFP19000.1 - 0.83 9.3 11.2 0.12 12.1 0.8 3.4 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family Csm2_III-A PF03750.13 KFP19000.1 - 2.5 8.9 8.1 0.7 10.7 2.0 3.1 2 1 0 2 2 2 0 Csm2 Type III-A UPF0016 PF01169.19 KFP19003.1 - 4.7e-45 151.8 19.7 4.7e-23 81.3 3.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Steroid_dh PF02544.16 KFP19004.1 - 1e-21 77.5 6.1 1.3e-21 77.1 4.9 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FB_lectin PF07367.11 KFP19004.1 - 0.035 14.0 0.1 0.063 13.2 0.1 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin SPC25 PF06703.11 KFP19004.1 - 1.1 9.0 5.7 4.4 7.1 2.1 2.4 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase_Tyr PF07714.17 KFP19005.1 - 2.4e-106 354.8 0.0 3.2e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP19005.1 - 4.9e-43 147.4 0.0 2.7e-30 105.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP19005.1 - 1.8e-25 89.3 4.7 7.7e-15 55.3 0.1 3.6 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 KFP19005.1 - 4.3e-24 84.4 0.1 1.8e-15 56.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain VEGFR-2_TMD PF17988.1 KFP19005.1 - 1.3e-18 66.1 4.6 2.7e-18 65.1 4.6 1.6 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain ig PF00047.25 KFP19005.1 - 4.2e-18 65.3 0.5 2.6e-10 40.3 0.1 4.0 4 1 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 KFP19005.1 - 8.4e-18 64.5 2.0 1.8e-10 41.0 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KFP19005.1 - 8.5e-07 29.1 1.0 0.43 10.8 0.0 4.3 3 2 1 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP19005.1 - 2.2e-05 24.4 0.5 1 9.5 0.0 3.7 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KFP19005.1 - 0.00077 19.5 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP19005.1 - 0.011 16.0 0.7 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP19005.1 - 0.013 15.0 0.1 8.4 6.0 0.0 2.7 2 0 0 2 2 2 0 Immunoglobulin domain Haspin_kinase PF12330.8 KFP19005.1 - 0.022 13.7 1.0 0.036 13.0 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Adeno_E3_CR1 PF02440.15 KFP19005.1 - 0.28 11.0 2.0 4.8 7.0 0.3 2.8 2 2 0 2 2 2 0 Adenovirus E3 region protein CR1 Ehrlichia_rpt PF09528.10 KFP19005.1 - 1.3 8.5 3.2 0.99 8.9 0.5 2.1 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Pkinase_Tyr PF07714.17 KFP19006.1 - 4.1e-104 347.5 0.0 6.5e-104 346.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP19006.1 - 2.9e-42 144.9 0.0 2.3e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP19006.1 - 1.6e-27 95.9 7.5 1.8e-08 34.8 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFP19006.1 - 9.1e-23 80.1 3.3 1.1e-08 35.0 0.0 5.8 5 1 1 6 6 6 4 Immunoglobulin I-set domain ig PF00047.25 KFP19006.1 - 4.6e-14 52.4 13.1 4.1e-09 36.5 0.1 5.6 5 1 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 KFP19006.1 - 5e-11 42.8 7.4 0.0029 17.9 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KFP19006.1 - 3.6e-05 23.9 10.0 0.45 10.7 0.0 6.0 6 1 1 7 7 7 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP19006.1 - 0.0015 18.1 0.5 0.55 9.9 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Ig_5 PF16681.5 KFP19006.1 - 0.0045 17.4 0.2 2.6 8.5 0.1 3.5 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain APH PF01636.23 KFP19006.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 KFP19007.1 - 9.1e-51 172.6 1.9 9.1e-51 172.6 1.9 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ELMO_CED12 PF04727.13 KFP19007.1 - 0.051 13.7 0.1 0.25 11.5 0.0 1.9 1 1 0 2 2 2 0 ELMO/CED-12 family TAFA PF12020.8 KFP19016.1 - 1.4e-44 150.5 9.9 1.6e-44 150.3 9.9 1.0 1 0 0 1 1 1 1 TAFA family Pkinase PF00069.25 KFP19026.1 - 1.2e-72 244.4 0.0 3.3e-72 243.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19026.1 - 2.2e-39 135.3 0.0 3.7e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFP19026.1 - 2.1e-12 46.7 0.1 4.2e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KFP19026.1 - 7.6e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP19026.1 - 6.2e-05 22.4 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP19026.1 - 0.00061 18.8 0.4 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFP19026.1 - 0.00083 19.3 0.0 0.022 14.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP19026.1 - 0.022 14.3 0.0 0.095 12.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 KFP19026.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PAX PF00292.18 KFP19027.1 - 2.3e-75 250.5 0.7 3.6e-75 249.8 0.7 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.8 KFP19027.1 - 1.8e-34 118.2 3.0 1.8e-34 118.2 3.0 2.0 2 0 0 2 2 2 1 Paired-box protein 2 C terminal HTH_32 PF13565.6 KFP19027.1 - 2.8e-06 27.8 0.2 0.0025 18.4 0.0 2.5 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 KFP19027.1 - 3.9e-05 23.3 0.0 8.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KFP19027.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 KFP19027.1 - 0.058 13.0 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 InsA C-terminal domain Homeodomain PF00046.29 KFP19027.1 - 0.099 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Homeodomain zf-CCHC PF00098.23 KFP19029.1 - 2.8e-09 36.6 43.0 6.5e-06 26.0 0.8 5.3 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 KFP19029.1 - 0.00024 20.8 37.7 0.0082 15.9 1.6 5.4 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.6 KFP19029.1 - 0.0005 20.0 3.6 0.0029 17.5 0.5 5.1 2 1 3 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 KFP19029.1 - 0.06 13.1 31.0 0.38 10.5 0.8 5.2 4 1 1 5 5 5 0 Zinc knuckle 2-Hacid_dh_C PF02826.19 KFP19030.1 - 8.2e-55 184.9 0.0 9.6e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFP19030.1 - 5.9e-07 30.0 0.0 9.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFP19030.1 - 9.3e-07 29.1 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFP19030.1 - 0.025 14.1 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh PF00389.30 KFP19030.1 - 0.028 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 KFP19030.1 - 0.056 12.8 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 KFP19030.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFP19030.1 - 0.099 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Gp_dh_N PF00044.24 KFP19030.1 - 0.21 11.9 0.4 0.43 10.9 0.4 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RNA_pol_I_A49 PF06870.12 KFP19031.1 - 6.6e-68 229.3 0.0 1e-67 228.7 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Mito_carr PF00153.27 KFP19032.1 - 2.5e-34 117.1 0.3 2e-11 43.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Eapp_C PF10238.9 KFP19032.1 - 0.23 11.6 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein WD40 PF00400.32 KFP19033.1 - 5.4e-12 46.0 12.0 0.0004 21.1 0.8 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19033.1 - 7.4e-05 23.0 0.0 7.1 7.0 0.1 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KFP19033.1 - 0.042 13.8 0.1 7.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal CMD PF02627.20 KFP19034.1 - 1.4e-13 50.7 0.2 9.9e-13 48.0 0.1 2.0 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 KFP19034.1 - 0.0011 18.0 0.0 0.0014 17.7 0.0 1.2 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF1961 PF09224.11 KFP19034.1 - 0.089 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) tRNA_m1G_MT PF01746.21 KFP19035.1 - 4.9e-23 81.9 0.1 5.7e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase FERM_M PF00373.18 KFP19036.1 - 6e-14 52.5 1.9 8.7e-14 51.9 0.3 2.2 2 0 0 2 2 2 1 FERM central domain Jak1_Phl PF17887.1 KFP19036.1 - 0.00018 21.5 0.1 0.00043 20.3 0.1 1.6 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain LRR_8 PF13855.6 KFP19045.1 - 9.3e-33 111.8 30.6 2.8e-13 49.4 6.4 5.4 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KFP19045.1 - 2.4e-18 65.9 29.5 0.00012 22.4 2.7 7.4 3 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP19045.1 - 4.6e-10 39.6 0.0 3.3e-06 27.1 0.0 3.5 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP19045.1 - 1.2e-06 28.1 8.9 0.024 14.1 0.1 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRRNT PF01462.18 KFP19045.1 - 7.8e-05 22.2 2.6 7.8e-05 22.2 2.6 3.8 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 KFP19045.1 - 0.00023 21.5 0.1 0.00069 20.0 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain fn3 PF00041.21 KFP19045.1 - 0.00029 21.1 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.33 KFP19045.1 - 0.00096 19.4 17.5 2.9 8.8 0.1 9.1 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_6 PF13516.6 KFP19045.1 - 0.083 13.0 26.5 1.4 9.2 0.2 7.4 8 0 0 8 8 8 0 Leucine Rich repeat Syndecan PF01034.20 KFP19045.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Glyco_transf_18 PF15024.6 KFP19047.1 - 5.3e-265 880.3 0.7 6.6e-265 880.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.6 KFP19047.1 - 1.9e-64 215.5 0.1 3.2e-64 214.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) Cation_efflux PF01545.21 KFP19048.1 - 0.00018 21.3 2.5 0.00018 21.3 2.5 3.4 2 2 1 3 3 3 3 Cation efflux family DUF2157 PF09925.9 KFP19048.1 - 5 6.9 10.1 31 4.3 10.1 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF805 PF05656.14 KFP19048.1 - 8.3 6.9 10.4 29 5.1 10.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Amidohydro_2 PF04909.14 KFP19049.1 - 7.3e-64 216.3 0.0 8.8e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Cyclin_N PF00134.23 KFP19050.1 - 9.8e-16 57.7 1.6 1.4e-12 47.4 0.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP19050.1 - 7.6 6.6 10.6 5.1 7.2 0.1 3.4 4 0 0 4 4 4 0 Cyclin, C-terminal domain Pkinase PF00069.25 KFP19051.1 - 1.4e-55 188.5 0.0 1.6e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19051.1 - 2.2e-38 132.0 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19051.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP19051.1 - 0.00047 19.1 0.0 0.00059 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP19051.1 - 0.0011 19.0 0.1 0.0031 17.5 0.1 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFP19051.1 - 0.11 11.5 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Rab3-GTPase_cat PF13890.6 KFP19052.1 - 3.4e-68 228.4 0.0 1.6e-67 226.2 0.0 2.1 3 0 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit SNF2_N PF00176.23 KFP19053.1 - 2.7e-32 111.9 0.1 4.6e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP19053.1 - 3.4e-16 59.6 0.3 1.4e-14 54.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP19053.1 - 3.5e-11 43.4 0.7 1.1e-09 38.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HNH PF01844.23 KFP19053.1 - 1.2e-08 35.0 0.0 1.2e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease ERCC3_RAD25_C PF16203.5 KFP19053.1 - 0.0022 17.3 0.1 0.0049 16.1 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KFP19053.1 - 0.024 14.6 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain HNH_5 PF14279.6 KFP19053.1 - 0.037 13.9 0.1 0.037 13.9 0.1 3.7 4 0 0 4 4 4 0 HNH endonuclease Transketolase_C PF02780.20 KFP19053.1 - 0.04 13.8 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain zf-RanBP PF00641.18 KFP19053.1 - 0.17 11.2 13.9 0.013 14.8 7.8 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others R3H PF01424.22 KFP19054.1 - 3.9e-12 46.0 0.0 1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 KFP19054.1 - 8.3e-12 45.7 6.4 8.3e-12 45.7 6.4 4.5 4 0 0 4 4 4 1 SUZ domain UBX PF00789.20 KFP19055.1 - 6.3e-19 68.0 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain tRNA-synt_2 PF00152.20 KFP19056.1 - 8.3e-78 261.6 0.1 1e-77 261.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFP19056.1 - 8.7e-10 38.5 0.9 1.6e-09 37.6 0.9 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFP19056.1 - 7.6e-05 22.3 0.2 0.38 10.2 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 KFP19056.1 - 0.006 16.7 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain S-AdoMet_synt_N PF00438.20 KFP19056.1 - 0.015 16.0 0.3 0.094 13.4 0.2 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain 7tm_1 PF00001.21 KFP19057.1 - 4e-51 173.9 14.4 4.9e-51 173.6 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.8 KFP19057.1 - 2.3e-19 69.3 5.6 4e-19 68.5 5.6 1.4 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.9 KFP19057.1 - 0.0018 17.7 14.7 0.0027 17.1 14.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TctB PF07331.11 KFP19057.1 - 0.37 11.1 10.7 0.15 12.3 2.1 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family COX2_TM PF02790.15 KFP19057.1 - 0.47 10.6 0.1 0.47 10.6 0.1 2.7 3 1 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain TSP_1 PF00090.19 KFP19058.1 - 5.9e-47 157.7 212.4 1.4e-09 38.0 7.4 23.1 23 1 0 23 23 23 14 Thrombospondin type 1 domain AfaD PF05775.12 KFP19058.1 - 0.08 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein Methyltransf_23 PF13489.6 KFP19059.1 - 1.1e-17 64.3 0.0 1.6e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP19059.1 - 1.2e-07 32.4 0.0 2.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP19059.1 - 0.0006 19.6 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DsrC PF04358.13 KFP19059.1 - 0.052 14.1 0.8 0.12 12.9 0.8 1.6 1 0 0 1 1 1 0 DsrC like protein Methyltransf_16 PF10294.9 KFP19059.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase BTB PF00651.31 KFP19060.1 - 7.3e-35 119.6 0.7 4.2e-34 117.1 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 KFP19060.1 - 1.4e-06 28.4 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 MATH domain Neurexophilin PF06312.12 KFP19061.1 - 3.2e-97 324.1 4.4 3.5e-97 324.0 4.4 1.0 1 0 0 1 1 1 1 Neurexophilin Nepo_coat_C PF03688.14 KFP19061.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain EGF PF00008.27 KFP19064.1 - 3.4e-09 36.8 22.6 7.8e-06 26.1 5.7 4.6 5 0 0 5 5 5 2 EGF-like domain hEGF PF12661.7 KFP19064.1 - 0.00053 20.5 16.0 0.0021 18.6 5.9 5.7 5 1 0 5 5 5 2 Human growth factor-like EGF VWD PF00094.25 KFP19066.1 - 0.00064 20.0 0.3 0.0033 17.7 0.3 2.0 2 0 0 2 2 2 1 von Willebrand factor type D domain RVT_1 PF00078.27 KFP19067.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_5 PF00266.19 KFP19069.1 - 2.1e-14 53.3 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.27 KFP19070.1 - 9.7e-54 181.3 1.2 1.2e-52 177.7 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain RPEL PF02755.15 KFP19070.1 - 0.025 14.3 0.5 0.077 12.7 0.5 1.9 1 0 0 1 1 1 0 RPEL repeat DUF3524 PF12038.8 KFP19071.1 - 8.2e-73 243.8 0.2 1.9e-72 242.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 KFP19071.1 - 4.2e-05 23.2 0.0 7.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-H2C2_2 PF13465.6 KFP19072.1 - 1.3e-32 110.7 61.1 1.2e-07 31.8 5.1 8.7 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP19072.1 - 3.2e-25 87.1 72.8 0.00012 22.4 5.0 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19072.1 - 5.4e-16 57.9 69.3 0.0049 17.6 1.0 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP19072.1 - 2.8e-08 33.8 56.5 0.01 16.1 1.9 9.1 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFP19072.1 - 3e-08 33.8 1.9 3e-08 33.8 1.9 4.3 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFP19072.1 - 3.7e-08 33.5 54.5 0.0087 16.4 0.4 8.4 8 0 0 8 8 8 4 Zinc-finger of C2H2 type Homeodomain PF00046.29 KFP19072.1 - 0.00013 21.7 0.0 0.00072 19.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain zf-H2C2_5 PF13909.6 KFP19072.1 - 0.0019 17.9 0.4 0.0019 17.9 0.4 6.1 6 1 0 6 6 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFP19072.1 - 0.018 15.0 68.2 0.029 14.4 1.5 8.5 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP19072.1 - 0.02 15.2 1.1 0.02 15.2 1.1 7.2 4 3 3 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFP19072.1 - 2.7 7.8 33.6 0.11 12.3 0.5 6.7 7 0 0 7 7 7 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 KFP19072.1 - 3.2 8.6 29.5 0.33 11.7 1.5 5.2 4 1 1 5 5 5 0 zinc-ribbon family zf-RING_7 PF02591.15 KFP19072.1 - 3.9 7.7 8.8 9.2 6.5 0.0 4.2 4 0 0 4 4 4 0 C4-type zinc ribbon domain Actin_micro PF17003.5 KFP19072.1 - 7.9 5.5 18.6 4.8 6.2 3.4 4.3 2 2 1 3 3 3 0 Putative actin-like family RVT_1 PF00078.27 KFP19073.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G-gamma PF00631.22 KFP19075.1 - 3.7e-20 71.7 0.0 4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain FtsX_ECD PF18075.1 KFP19075.1 - 0.016 15.8 0.1 0.019 15.6 0.1 1.0 1 0 0 1 1 1 0 FtsX extracellular domain CP12 PF02672.15 KFP19075.1 - 0.027 15.2 0.2 0.034 14.9 0.2 1.2 1 0 0 1 1 1 0 CP12 domain CHASE8 PF17152.4 KFP19075.1 - 0.089 13.0 0.1 0.097 12.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic sensor domain RLL PF10036.9 KFP19076.1 - 6e-83 278.6 1.7 6.7e-83 278.5 1.7 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Cactin_mid PF10312.9 KFP19076.1 - 0.00099 18.9 0.2 0.0014 18.4 0.2 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin Thioredoxin_6 PF13848.6 KFP19078.1 - 2.8e-26 92.6 0.0 8.7e-22 77.9 0.0 3.7 3 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFP19078.1 - 2e-12 47.0 0.0 1.8e-11 44.0 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin FAM150 PF15129.6 KFP19078.1 - 2.8 8.1 4.3 5.9 7.1 4.3 1.4 1 0 0 1 1 1 0 FAM150 family DUF389 PF04087.14 KFP19079.1 - 0.32 11.0 4.5 0.27 11.2 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF389) ERO1 PF04137.15 KFP19080.1 - 4e-120 401.2 0.0 4.6e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DHHC PF01529.20 KFP19081.1 - 1.6e-36 125.4 7.8 1.6e-36 125.4 7.8 1.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase Med19 PF10278.9 KFP19082.1 - 2.2e-78 262.3 13.3 2.5e-78 262.1 13.3 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Connexin PF00029.19 KFP19082.1 - 0.005 16.6 0.4 0.0063 16.3 0.4 1.1 1 0 0 1 1 1 1 Connexin Zip PF02535.22 KFP19082.1 - 0.023 13.9 2.0 0.025 13.8 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.11 KFP19082.1 - 0.82 9.7 24.9 1.4 8.9 24.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.8 KFP19082.1 - 4.6 5.9 12.3 5.8 5.6 12.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 KFP19082.1 - 9.7 5.9 12.4 13 5.5 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Thioredoxin PF00085.20 KFP19083.1 - 4e-11 42.8 0.0 7.1e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Arm PF00514.23 KFP19084.1 - 3.3e-29 100.0 5.0 3e-08 33.4 0.0 6.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP19084.1 - 8.5e-05 23.0 0.7 0.54 10.8 0.0 4.1 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KFP19084.1 - 0.00037 20.8 0.4 2.3 8.6 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KFP19084.1 - 0.022 15.0 1.0 14 6.3 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat Ebp2 PF05890.12 KFP19084.1 - 0.081 12.5 0.8 0.15 11.6 0.8 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Atx10homo_assoc PF09759.9 KFP19084.1 - 0.11 12.6 3.1 0.36 10.9 0.0 3.2 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain FAM176 PF14851.6 KFP19085.1 - 1.3e-63 213.0 0.2 1.5e-63 212.8 0.2 1.0 1 0 0 1 1 1 1 FAM176 family VirB3 PF05101.13 KFP19085.1 - 0.006 16.8 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein DUF4576 PF15144.6 KFP19085.1 - 0.073 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DUF555 PF04475.12 KFP19085.1 - 0.14 12.5 0.4 2.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF555) DUF755 PF05501.11 KFP19085.1 - 3 8.2 6.9 4.4 7.6 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_L19 PF01245.20 KFP19086.1 - 8e-17 61.2 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 DUF4108 PF13390.6 KFP19086.1 - 0.037 14.0 0.9 1.6 8.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4108) GCFC PF07842.12 KFP19087.1 - 2.5e-26 92.9 3.5 2.5e-26 92.9 3.5 2.3 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein RecQ_Zn_bind PF16124.5 KFP19087.1 - 0.52 11.1 9.0 2.5e+02 2.5 6.2 3.9 2 1 0 2 2 2 0 RecQ zinc-binding JIP_LZII PF16471.5 KFP19087.1 - 0.82 9.9 8.6 0.31 11.3 2.6 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II CDC45 PF02724.14 KFP19088.1 - 6.4 4.9 8.7 7.7 4.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PH_13 PF16652.5 KFP19089.1 - 2.6e-71 238.5 0.9 2.6e-71 238.5 0.9 3.9 3 2 2 5 5 2 1 Pleckstrin homology domain SH3_9 PF14604.6 KFP19089.1 - 2e-66 219.7 3.1 1.3e-15 57.0 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.28 KFP19089.1 - 2e-65 216.2 9.1 9.9e-16 57.1 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.17 KFP19089.1 - 1.1e-59 197.9 0.5 2.3e-13 49.6 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.20 KFP19089.1 - 2.3e-43 148.5 0.1 2.3e-43 148.5 0.1 3.4 2 1 0 2 2 1 1 RhoGEF domain EF-hand_4 PF12763.7 KFP19089.1 - 1.2e-29 102.3 0.0 2.4e-13 49.9 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.30 KFP19089.1 - 2.1e-22 79.4 0.0 5.1e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 KFP19089.1 - 1.4e-09 36.8 0.2 0.0046 16.4 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP19089.1 - 1.1e-07 31.2 0.5 0.64 10.1 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KFP19089.1 - 1.6e-07 31.7 0.5 0.00057 20.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair PH PF00169.29 KFP19089.1 - 0.00074 20.0 0.1 0.0023 18.4 0.1 1.9 1 0 0 1 1 1 1 PH domain EF-hand_8 PF13833.6 KFP19089.1 - 0.019 14.8 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KFP19089.1 - 0.031 13.8 0.9 8.9 6.0 0.1 3.3 3 0 0 3 3 3 0 EF hand DUF3800 PF12686.7 KFP19089.1 - 0.8 10.3 3.0 2.7e+02 2.2 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3800) INTAP PF16617.5 KFP19089.1 - 5.8 7.3 12.3 0.12 12.7 2.7 2.8 2 1 1 3 3 3 0 Intersectin and clathrin adaptor AP2 binding region RNA_pol_Rpb2_45 PF10385.9 KFP19090.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain Profilin PF00235.19 KFP19091.1 - 7.2e-25 87.7 0.0 7.9e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Profilin RRM_1 PF00076.22 KFP19092.1 - 1.5e-16 60.0 0.3 1.2e-15 57.0 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP19092.1 - 0.00021 20.9 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FKBP_C PF00254.28 KFP19093.1 - 1.1e-28 99.3 0.0 1.3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WDCP PF15390.6 KFP19094.1 - 0 1090.9 0.0 0 1090.7 0.0 1.0 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family ANAPC4_WD40 PF12894.7 KFP19094.1 - 0.0039 17.5 0.4 0.021 15.1 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 KFP19095.1 - 0 1045.9 0.3 0 1045.7 0.3 1.0 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family TPR_MLP1_2 PF07926.12 KFP19095.1 - 0.14 12.3 0.3 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MFS_2 PF13347.6 KFP19096.1 - 5.2e-94 315.2 17.7 4.7e-93 312.1 17.7 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KFP19096.1 - 2.2e-09 36.7 28.8 3.1e-08 32.9 25.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Collectrin PF16959.5 KFP19096.1 - 0.84 9.4 2.6 14 5.4 0.0 2.8 3 0 0 3 3 3 0 Renal amino acid transporter SEP PF08059.13 KFP19097.1 - 1.3e-27 96.2 0.5 6.2e-27 94.0 0.2 2.1 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KFP19097.1 - 7.5e-15 54.9 0.1 2.1e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 UBX domain AAA PF00004.29 KFP19098.1 - 1.8e-47 161.1 0.0 1.2e-40 139.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KFP19098.1 - 2.4e-17 62.8 0.1 6.4e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KFP19098.1 - 3.5e-12 45.9 0.0 1.1e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFP19098.1 - 5e-08 33.5 0.1 0.00033 21.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 KFP19098.1 - 7e-06 25.9 0.0 3.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KFP19098.1 - 8.9e-05 22.7 0.0 0.00029 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP19098.1 - 0.0006 20.1 0.1 0.05 13.9 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP19098.1 - 0.0051 16.8 0.1 0.059 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFP19098.1 - 0.0056 16.2 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF1088 PF06469.11 KFP19098.1 - 0.011 15.4 1.4 0.026 14.2 1.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) RNA_helicase PF00910.22 KFP19098.1 - 0.013 15.8 0.0 0.058 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 KFP19098.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KFP19098.1 - 0.015 15.4 0.0 1.4 9.0 0.0 2.8 2 1 1 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFP19098.1 - 0.015 14.7 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KFP19098.1 - 0.023 14.7 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KFP19098.1 - 0.027 14.2 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFP19098.1 - 0.028 14.9 2.0 0.076 13.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFP19098.1 - 0.045 12.9 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 KFP19098.1 - 0.057 13.1 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KFP19098.1 - 0.11 12.4 0.0 0.65 9.9 0.1 2.3 2 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KFP19098.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFP19098.1 - 0.19 11.4 0.0 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KFP19098.1 - 0.41 10.4 0.0 0.41 10.4 0.0 3.2 4 1 0 4 4 2 0 AAA domain DUF4746 PF15928.5 KFP19098.1 - 0.51 9.7 4.5 0.94 8.8 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4636 PF15468.6 KFP19098.1 - 1.4 8.5 5.5 0.56 9.9 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) Rnk_N PF14760.6 KFP19099.1 - 0.092 13.2 1.3 7.2 7.2 1.3 2.5 1 1 0 1 1 1 0 Rnk N-terminus Kelch_1 PF01344.25 KFP19100.1 - 4.8e-46 154.1 12.2 1.5e-13 50.1 0.0 6.4 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 KFP19100.1 - 6.3e-45 150.1 5.8 2e-10 40.6 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFP19100.1 - 1.7e-30 105.1 0.2 1.7e-30 105.1 0.2 1.6 2 0 0 2 2 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP19100.1 - 2.5e-28 97.8 2.8 1.3e-09 37.9 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 KFP19100.1 - 8.7e-24 83.9 0.9 2.3e-23 82.6 0.9 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KFP19100.1 - 3.8e-23 80.5 2.9 9.3e-06 25.4 0.0 6.9 6 1 1 7 7 7 4 Kelch motif Kelch_3 PF13415.6 KFP19100.1 - 4e-15 55.7 1.8 0.0021 18.3 0.0 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP19100.1 - 1.1e-14 54.0 18.0 0.0048 16.8 0.1 6.5 7 0 0 7 7 7 4 Kelch motif DUF1668 PF07893.13 KFP19100.1 - 0.0035 16.7 0.0 0.08 12.3 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1668) DUF3342 PF11822.8 KFP19100.1 - 0.022 14.9 0.2 0.17 12.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KFP19100.1 - 0.054 14.0 3.9 16 6.1 0.1 4.1 4 0 0 4 4 4 0 PQQ-like domain IGPS PF00218.21 KFP19100.1 - 0.059 12.5 0.4 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF1943 PF09172.11 KFP19101.1 - 1.5e-71 241.2 0.3 1.5e-71 241.2 0.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1943) Vitellogenin_N PF01347.22 KFP19101.1 - 4.9e-63 213.5 0.1 4.9e-63 213.5 0.1 2.8 3 0 0 3 3 3 1 Lipoprotein amino terminal region DUF1081 PF06448.11 KFP19101.1 - 1.6e-38 131.6 0.0 3.2e-37 127.4 0.0 3.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1081) ApoB100_C PF12491.8 KFP19101.1 - 1.5e-24 85.7 2.7 1.5e-24 85.7 2.7 5.3 6 0 0 6 6 6 1 Apolipoprotein B100 C terminal EST1 PF10374.9 KFP19101.1 - 0.018 15.7 0.1 0.018 15.7 0.1 4.8 2 1 0 3 3 3 0 Telomerase activating protein Est1 DUF2164 PF09932.9 KFP19101.1 - 0.33 11.0 8.1 0.72 10.0 0.2 4.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) LIDHydrolase PF10230.9 KFP19102.1 - 5.5e-86 288.4 0.0 6.5e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KFP19102.1 - 0.00086 19.2 0.0 0.005 16.7 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_6 PF12697.7 KFP19102.1 - 0.0016 19.1 0.0 0.0017 19.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP19102.1 - 0.0061 15.8 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFP19102.1 - 0.025 13.5 0.1 0.08 11.8 0.0 1.9 2 1 1 3 3 3 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KFP19102.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.12 KFP19102.1 - 0.065 12.7 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) TGF_beta PF00019.20 KFP19103.1 - 6.5e-34 117.0 0.5 9.6e-34 116.5 0.5 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP19103.1 - 8.5e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide PX PF00787.24 KFP19104.1 - 1.9e-13 50.4 1.1 3.5e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 PX domain Syndecan PF01034.20 KFP19105.1 - 2.6e-27 94.5 0.0 3.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 KFP19105.1 - 0.04 14.1 0.5 0.17 12.1 0.0 2.2 2 1 1 3 3 3 0 Glycophorin A TssR PF17643.1 KFP19105.1 - 0.27 9.1 0.1 0.34 8.8 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR PUF PF00806.19 KFP19106.1 - 3e-74 240.7 8.7 1.1e-09 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KFP19106.1 - 0.021 15.2 1.2 5.6 7.3 0.1 3.9 1 1 3 4 4 4 0 CPL (NUC119) domain sCache_2 PF17200.4 KFP19106.1 - 0.029 14.2 0.2 52 3.6 0.0 4.1 4 0 0 4 4 4 0 Single Cache domain 2 Mt_ATP-synt_B PF05405.14 KFP19106.1 - 3.9 7.1 6.0 9.6 5.8 0.2 3.3 3 1 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease_2 PF13520.6 KFP19107.1 - 1e-55 189.3 45.7 1.4e-55 188.9 45.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP19107.1 - 6.6e-22 77.7 42.7 9.6e-22 77.2 42.4 1.3 1 1 0 1 1 1 1 Amino acid permease Ras PF00071.22 KFP19108.1 - 9.9e-39 132.5 0.0 1.1e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP19108.1 - 4.1e-18 65.7 0.0 5.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP19108.1 - 7.2e-11 41.8 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP19108.1 - 0.0067 15.9 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP19108.1 - 0.0072 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP19108.1 - 0.024 14.6 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFP19108.1 - 0.16 11.7 0.1 3.3 7.5 0.1 2.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFP19109.1 - 2e-56 190.1 0.0 2.4e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP19109.1 - 7.9e-22 77.7 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP19109.1 - 6.8e-10 38.7 0.0 1.2e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP19109.1 - 0.00011 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP19109.1 - 0.031 14.2 0.0 0.081 12.8 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase Gtr1_RagA PF04670.12 KFP19109.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region 7tm_4 PF13853.6 KFP19110.1 - 9.4e-18 64.9 1.4 1.1e-17 64.7 1.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19110.1 - 0.086 12.1 2.3 0.14 11.5 2.3 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Med24_N PF11277.8 KFP19111.1 - 0 1340.8 22.7 0 1340.6 22.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal Med8 PF10232.9 KFP19111.1 - 0.071 12.7 2.1 0.13 11.8 2.1 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 ORMDL PF04061.14 KFP19112.1 - 4.3e-54 182.0 4.6 4.9e-54 181.8 4.6 1.0 1 0 0 1 1 1 1 ORMDL family LRR_8 PF13855.6 KFP19113.1 - 1.2e-17 63.4 4.4 2.7e-11 43.0 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP19113.1 - 8.9e-08 32.3 5.4 0.041 14.3 2.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) DUF3700 PF12481.8 KFP19113.1 - 0.00082 18.9 0.0 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein LRR_6 PF13516.6 KFP19113.1 - 0.002 18.0 4.7 0.49 10.6 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRRNT PF01462.18 KFP19113.1 - 0.0056 16.3 0.1 0.016 14.8 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KFP19113.1 - 0.0097 16.3 11.0 0.13 12.9 0.4 4.7 4 1 0 4 4 4 1 Leucine Rich Repeat zf-H2C2_2 PF13465.6 KFP19114.1 - 8.3e-25 86.1 28.1 4.7e-07 29.9 3.8 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP19114.1 - 1.6e-16 59.8 38.5 7.6e-06 26.1 0.4 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19114.1 - 3.8e-12 45.9 39.0 0.00019 22.0 0.3 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP19114.1 - 0.00067 19.4 32.4 0.0027 17.4 0.1 5.4 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KFP19114.1 - 0.0043 16.8 0.2 0.0043 16.8 0.2 4.6 5 1 0 5 5 4 1 zinc-finger C2H2-type GAGA PF09237.11 KFP19114.1 - 0.07 13.0 2.6 0.1 12.4 0.1 2.4 1 1 0 2 2 2 0 GAGA factor zf-C2HE PF16278.5 KFP19114.1 - 0.084 13.3 16.4 0.57 10.7 0.8 4.4 2 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFP19114.1 - 0.11 12.5 40.3 0.5 10.4 0.1 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger DUF3268 PF11672.8 KFP19114.1 - 0.19 12.1 0.3 0.19 12.1 0.3 3.1 3 1 0 3 3 3 0 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 KFP19114.1 - 0.69 10.3 23.7 2.3 8.6 0.3 5.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 KFP19114.1 - 3.4 8.0 9.4 31 4.9 0.1 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain AKAP95 PF04988.12 KFP19114.1 - 7.1 6.8 8.0 3.8 7.7 0.4 2.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) adh_short PF00106.25 KFP19115.1 - 1.5e-33 115.9 0.0 1.8e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP19115.1 - 8.6e-23 81.1 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP19115.1 - 3.1e-05 24.0 0.0 4.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Rdx PF10262.9 KFP19116.1 - 2e-14 53.5 0.0 2.3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Rdx family MENTAL PF10457.9 KFP19117.1 - 2.1e-62 210.1 8.2 2.1e-62 210.1 8.2 1.5 2 0 0 2 2 2 1 Cholesterol-capturing domain START PF01852.19 KFP19117.1 - 2.2e-47 161.2 0.0 3.1e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 START domain Excalibur PF05901.11 KFP19118.1 - 0.38 11.4 1.4 10 6.8 0.1 3.6 2 2 1 3 3 3 0 Excalibur calcium-binding domain DUF2345 PF10106.9 KFP19118.1 - 1.2 9.0 15.7 0.049 13.5 4.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Pkinase PF00069.25 KFP19119.1 - 1.5e-44 152.4 0.0 1.7e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19119.1 - 2.1e-40 138.6 0.0 2.7e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP19119.1 - 0.0064 15.3 0.0 0.0089 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP19119.1 - 0.06 13.3 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFP19119.1 - 0.099 12.2 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 RIO1 family KH_1 PF00013.29 KFP19120.1 - 7.3e-32 109.0 8.2 1.6e-16 59.8 1.1 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KFP19120.1 - 2.7e-11 43.1 3.5 2.9e-05 23.8 0.0 2.7 2 1 1 3 3 3 2 KH domain KH_4 PF13083.6 KFP19120.1 - 5.2e-05 23.1 0.8 0.049 13.5 0.3 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KFP19120.1 - 0.0081 16.2 3.3 1.5 9.0 0.6 2.4 2 0 0 2 2 2 2 NusA-like KH domain NFRKB_winged PF14465.6 KFP19121.1 - 8.1e-33 112.7 1.7 3.8e-32 110.6 1.0 2.4 2 0 0 2 2 2 1 NFRKB Winged Helix-like Apt1 PF10351.9 KFP19121.1 - 0.14 11.0 3.1 0.067 12.0 0.3 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain ATP-synt_E PF05680.12 KFP19121.1 - 0.56 10.6 8.2 0.82 10.0 2.0 2.8 2 0 0 2 2 2 0 ATP synthase E chain Trypsin PF00089.26 KFP19122.1 - 1.6e-67 227.5 0.4 3.2e-67 226.6 0.4 1.5 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.18 KFP19122.1 - 1.2e-36 124.6 74.5 9.4e-10 38.5 9.3 4.6 4 0 0 4 4 4 4 Low-density lipoprotein receptor domain class A CUB PF00431.20 KFP19122.1 - 1.4e-36 125.1 0.3 2.1e-19 69.9 0.4 2.6 2 0 0 2 2 2 2 CUB domain SEA PF01390.20 KFP19122.1 - 2.6e-12 46.7 0.3 7.9e-12 45.2 0.1 1.9 2 0 0 2 2 2 1 SEA domain DUF1986 PF09342.11 KFP19122.1 - 1.9e-05 25.0 0.0 6.1e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB_2 PF02408.20 KFP19122.1 - 0.00025 20.8 1.6 0.00055 19.7 0.7 2.1 2 0 0 2 2 2 1 CUB-like domain BTB PF00651.31 KFP19123.1 - 2.1e-29 102.0 0.6 3.6e-29 101.2 0.6 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP19123.1 - 4.7e-19 67.7 24.4 0.00014 22.1 0.4 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19123.1 - 4.1e-15 55.2 18.1 0.0022 18.7 0.4 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP19123.1 - 3.9e-13 49.2 23.1 2.8e-06 27.5 0.3 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.7 KFP19123.1 - 2.2e-10 40.5 19.4 0.013 15.8 0.3 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP19123.1 - 1.1e-08 34.9 24.1 0.0055 16.7 0.1 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP19123.1 - 1.3e-07 31.2 20.3 0.012 15.4 0.3 4.8 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFP19123.1 - 2.9e-06 27.4 9.5 0.025 14.9 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP19123.1 - 0.00014 22.1 13.0 0.3 11.4 2.4 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFP19123.1 - 0.0013 18.8 9.7 5.7 7.1 3.0 4.0 2 1 2 4 4 4 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KFP19123.1 - 0.011 16.3 6.9 0.36 11.5 0.4 3.8 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KFP19123.1 - 0.023 14.5 3.3 0.16 11.8 0.1 3.2 3 0 0 3 3 2 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KFP19123.1 - 0.027 14.9 13.7 0.21 12.1 0.0 4.9 3 1 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Glyco_tran_10_N PF17039.5 KFP19123.1 - 0.05 14.1 0.2 0.2 12.1 0.2 2.0 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal zf-H2C2_5 PF13909.6 KFP19123.1 - 0.097 12.5 0.1 0.097 12.5 0.1 3.0 3 0 0 3 3 2 0 C2H2-type zinc-finger domain Zn_Tnp_IS1595 PF12760.7 KFP19123.1 - 0.61 10.1 20.3 0.18 11.8 3.6 3.2 1 1 2 3 3 3 0 Transposase zinc-ribbon domain FYVE PF01363.21 KFP19123.1 - 0.81 9.9 14.5 4.1 7.6 4.5 4.1 1 1 1 2 2 2 0 FYVE zinc finger CpXC PF14353.6 KFP19123.1 - 1 9.4 9.2 43 4.2 6.4 3.6 1 1 2 3 3 3 0 CpXC protein zf-AN1 PF01428.16 KFP19123.1 - 2.2 8.5 12.3 6.1 7.1 0.1 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger C1_1 PF00130.22 KFP19123.1 - 3.1 7.8 9.6 1 9.3 3.8 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFP19123.1 - 3.4 7.3 11.0 2.2 7.9 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 KFP19123.1 - 4.6 7.5 12.5 3.1 8.1 6.2 3.5 3 1 0 3 3 3 0 LIM domain ADAM_CR_2 PF17771.1 KFP19124.1 - 6.2e-23 81.1 13.1 1.1e-20 73.9 7.3 5.0 4 1 1 5 5 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KFP19124.1 - 6e-19 68.7 0.0 8.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 KFP19124.1 - 6.3e-15 55.1 57.6 4.9e-12 45.9 9.0 6.5 6 0 0 6 6 6 3 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP19124.1 - 8.1e-14 51.6 0.2 1.3e-10 41.3 0.0 2.3 1 1 1 2 2 2 2 ADAM-TS Spacer 1 Reprolysin_3 PF13582.6 KFP19124.1 - 7.9e-12 45.8 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP19124.1 - 7.3e-10 39.3 0.1 1.4e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFP19124.1 - 1.2e-06 28.6 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP19124.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PXA PF02194.15 KFP19125.1 - 1.9e-31 109.5 0.0 8e-31 107.4 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFP19125.1 - 3e-22 79.3 0.5 1.5e-21 77.1 0.2 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KFP19125.1 - 6.8e-19 67.9 0.2 1.4e-18 66.9 0.2 1.5 1 0 0 1 1 1 1 PX domain TssC PF17541.2 KFP19125.1 - 0.054 12.3 0.1 0.08 11.8 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DUF1840 PF08895.11 KFP19125.1 - 0.14 12.5 0.1 0.46 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Ig_3 PF13927.6 KFP19126.1 - 4.7e-36 123.2 0.9 1e-14 54.9 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP19126.1 - 7.5e-36 122.1 0.4 5.6e-14 52.0 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP19126.1 - 1.7e-29 101.8 0.6 1.1e-14 54.4 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP19126.1 - 3.3e-28 97.8 0.9 7.4e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP19126.1 - 3.3e-15 56.2 2.9 0.00012 22.2 0.0 5.1 3 2 1 4 4 4 4 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP19126.1 - 9.6e-10 38.7 0.1 0.0073 16.7 0.0 3.6 3 1 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP19126.1 - 5.4e-07 29.6 0.1 0.012 15.7 0.0 3.3 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KFP19126.1 - 5.4e-06 25.9 0.0 0.6 9.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP19126.1 - 2.7e-05 24.1 0.2 0.057 13.5 0.1 2.6 3 0 0 3 3 2 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KFP19126.1 - 3.2e-05 24.1 0.1 0.27 11.5 0.0 3.6 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFP19126.1 - 0.0024 17.9 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Ig_C17orf99 PF17736.1 KFP19126.1 - 0.017 15.1 0.2 0.47 10.5 0.0 2.9 2 1 0 2 2 2 0 C17orf99 Ig domain C2-set PF05790.15 KFP19126.1 - 0.056 13.6 0.3 87 3.4 0.0 4.2 3 2 1 4 4 4 0 Immunoglobulin C2-set domain Ig_3 PF13927.6 KFP19127.1 - 3.7e-37 126.8 2.3 4.6e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP19127.1 - 7.9e-37 125.2 2.7 5.8e-15 55.1 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP19127.1 - 3.2e-28 97.7 4.4 6.9e-14 51.8 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP19127.1 - 1.2e-27 96.0 2.1 7.6e-11 42.2 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP19127.1 - 1.5e-14 54.1 7.1 4.8e-05 23.5 0.1 5.1 3 2 1 4 4 4 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KFP19127.1 - 2.5e-08 33.9 0.1 0.0066 16.5 0.0 3.5 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 KFP19127.1 - 4.3e-08 33.5 0.0 0.19 12.2 0.0 3.4 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP19127.1 - 5e-05 22.8 0.0 0.99 9.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KFP19127.1 - 7.9e-05 22.8 0.1 0.53 10.6 0.0 3.7 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFP19127.1 - 0.00017 21.6 0.8 0.35 10.9 0.1 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 KFP19127.1 - 0.011 15.7 0.3 0.79 9.8 0.0 2.6 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain VIT PF08487.10 KFP19128.1 - 7.7e-20 71.2 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 KFP19128.1 - 5.1e-08 32.7 0.3 1.2e-07 31.6 0.2 1.6 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain Laps PF10169.9 KFP19129.1 - 4.5e-37 127.5 18.8 4.3e-36 124.3 18.8 1.9 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 KFP19129.1 - 7.8e-05 22.8 8.0 7.8e-05 22.8 8.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Bax1-I PF01027.20 KFP19130.1 - 8.9e-49 166.1 29.0 1e-48 166.0 29.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 KFP19130.1 - 0.42 10.5 31.7 6.9 6.5 16.5 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling ubiquitin PF00240.23 KFP19132.1 - 9.2e-14 51.0 0.0 9.8e-14 50.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 KFP19132.1 - 0.04 14.0 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Myosin_head PF00063.21 KFP19135.1 - 2.8e-234 779.4 6.1 3.2e-234 779.2 6.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KFP19135.1 - 6.4e-13 48.3 1.4 6.4e-13 48.3 1.4 1.8 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFP19135.1 - 0.0094 16.2 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4537 PF15057.6 KFP19135.1 - 0.032 14.2 0.1 0.69 9.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) AAA_16 PF13191.6 KFP19135.1 - 0.089 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KFP19135.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KFP19135.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein fn3 PF00041.21 KFP19137.1 - 4.2e-10 39.8 0.0 8.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain SPRY PF00622.28 KFP19137.1 - 1.5e-07 31.5 0.0 2.8e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP19137.1 - 0.00036 20.1 0.1 0.0013 18.3 0.1 2.1 1 1 0 1 1 1 1 SPRY-associated domain ATP-synt_E_2 PF08112.11 KFP19137.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase epsilon subunit DUF2203 PF09969.9 KFP19137.1 - 0.18 12.6 1.5 0.32 11.7 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Laminin_G_2 PF02210.24 KFP19138.1 - 5.5e-25 88.4 0.7 7.1e-25 88.0 0.7 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFP19138.1 - 4.5e-15 56.0 0.1 6.5e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain F5_F8_type_C PF00754.25 KFP19138.1 - 2.1e-06 27.8 0.0 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain TLV_coat PF00429.19 KFP19142.1 - 0.0013 17.5 0.2 0.0014 17.4 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Cpn10 PF00166.21 KFP19144.1 - 3.6e-16 59.0 1.5 4.1e-16 58.8 1.5 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Sec2p PF06428.11 KFP19149.1 - 9.9e-09 35.1 10.2 9.9e-09 35.1 10.2 2.2 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p IATP PF04568.12 KFP19149.1 - 0.034 14.6 1.2 0.086 13.3 1.2 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Spc7 PF08317.11 KFP19149.1 - 0.079 11.8 13.6 0.13 11.1 13.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AviRa PF11599.8 KFP19149.1 - 0.096 12.1 0.7 0.14 11.6 0.7 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Cob_adeno_trans PF01923.18 KFP19149.1 - 0.28 11.3 4.3 1.9 8.6 4.2 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase UPF0242 PF06785.11 KFP19149.1 - 0.41 10.7 12.6 0.7 10.0 12.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2203 PF09969.9 KFP19149.1 - 0.51 11.1 4.3 1.2 9.9 4.3 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 KFP19149.1 - 0.54 9.6 4.6 0.81 9.0 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KFP19149.1 - 2 7.9 6.4 2.9 7.4 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFP19149.1 - 2.1 8.4 4.2 3.7 7.6 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HSP70 PF00012.20 KFP19149.1 - 3 5.9 9.9 0.72 8.0 6.9 1.4 2 0 0 2 2 2 0 Hsp70 protein Uds1 PF15456.6 KFP19149.1 - 3.2 7.9 15.7 0.87 9.8 6.9 2.5 1 1 1 2 2 2 0 Up-regulated During Septation OmpH PF03938.14 KFP19149.1 - 6.2 7.2 11.6 16 5.9 11.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KFP19149.1 - 8.3 7.0 9.3 18 6.0 7.8 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Bestrophin PF01062.21 KFP19150.1 - 3.6e-109 364.7 2.9 4.2e-109 364.5 2.9 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ferritin PF00210.24 KFP19151.1 - 1.6e-30 105.9 2.9 2e-30 105.6 2.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KFP19151.1 - 0.0084 16.5 1.1 0.011 16.2 1.1 1.3 1 1 0 1 1 1 1 Rubrerythrin 7tm_4 PF13853.6 KFP19152.1 - 3.9e-47 161.3 16.2 4.9e-47 161.0 16.2 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19152.1 - 3.9e-25 88.7 26.0 6.6e-25 87.9 26.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP19152.1 - 0.00048 19.8 15.0 0.00048 19.8 15.0 2.9 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx SLC3A2_N PF16028.5 KFP19152.1 - 0.16 11.5 2.4 0.92 9.1 0.1 2.6 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus 7tm_4 PF13853.6 KFP19153.1 - 3.3e-49 168.1 21.6 3.9e-49 167.9 21.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19153.1 - 5.2e-29 101.4 23.4 8.3e-29 100.7 23.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19153.1 - 0.00045 19.7 26.8 0.0009 18.7 26.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 KFP19154.1 - 1e-06 28.3 12.9 3e-06 26.8 12.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KFP19154.1 - 0.0011 18.6 1.2 0.0011 18.6 1.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc Pkinase PF00069.25 KFP19156.1 - 1.6e-65 221.1 0.0 3.1e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19156.1 - 7.4e-64 215.5 0.0 1e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP19156.1 - 0.0017 17.2 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF1476 PF07345.11 KFP19156.1 - 0.021 15.2 0.2 0.056 13.8 0.2 1.7 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta OmpH PF03938.14 KFP19156.1 - 0.057 13.8 4.1 0.11 12.8 4.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 KFP19156.1 - 0.24 10.8 11.6 0.46 9.9 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Pecanex_C PF05041.15 KFP19157.1 - 2e-119 397.2 0.0 2.9e-119 396.7 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DUF5392 PF17370.2 KFP19157.1 - 0.63 10.1 2.0 2.2 8.4 0.0 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5392) SPAR_C PF11881.8 KFP19158.1 - 4.5e-84 282.2 12.3 4.5e-84 282.2 12.3 2.8 2 0 0 2 2 1 1 C-terminal domain of SPAR protein Rap_GAP PF02145.15 KFP19158.1 - 5.9e-69 231.4 0.1 1.7e-68 229.8 0.1 1.8 2 0 0 2 2 2 1 Rap/ran-GAP PDZ_6 PF17820.1 KFP19158.1 - 4.7e-06 26.4 0.1 1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP19158.1 - 9.2e-05 22.7 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ATG16 PF08614.11 KFP19158.1 - 0.004 17.4 6.3 0.016 15.4 6.3 2.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4164 PF13747.6 KFP19158.1 - 0.0091 16.3 1.1 0.024 14.9 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Sec34 PF04136.15 KFP19158.1 - 0.013 15.4 0.9 0.035 14.0 0.9 1.7 1 0 0 1 1 1 0 Sec34-like family RasGAP_C PF03836.15 KFP19158.1 - 0.17 12.0 2.1 0.18 11.9 0.4 1.9 2 0 0 2 2 2 0 RasGAP C-terminus YabA PF06156.13 KFP19158.1 - 0.47 11.1 1.9 1.5 9.5 1.9 1.8 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KFP19158.1 - 0.52 10.8 10.1 1.4 9.4 10.1 1.7 1 0 0 1 1 1 0 Cell division protein ZapB CASP_C PF08172.12 KFP19158.1 - 1.5 8.1 8.3 0.039 13.3 0.5 2.4 2 0 0 2 2 2 0 CASP C terminal DLEU7 PF15760.5 KFP19159.1 - 1.4e-76 256.3 1.3 1.7e-76 256.1 1.3 1.0 1 0 0 1 1 1 1 Leukemia-associated protein 7 RNase_H2-Ydr279 PF09468.10 KFP19161.1 - 1.2e-14 54.8 1.2 2.4e-14 53.8 1.2 1.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KFP19161.1 - 1.5e-12 47.6 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain FAM124 PF15067.6 KFP19162.1 - 2.3e-107 358.0 0.0 3.1e-107 357.5 0.0 1.2 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.20 KFP19164.1 - 1.3e-84 284.7 0.8 1.4e-84 284.5 0.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_M8 PF01457.16 KFP19164.1 - 0.08 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Leishmanolysin INT_SG_DDX_CT_C PF15300.6 KFP19165.1 - 3.1e-26 90.9 4.2 7.2e-26 89.8 4.2 1.7 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 KFP19165.1 - 8.1e-06 26.4 0.0 2.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.32 KFP19166.1 - 8.7e-21 73.9 14.2 3.9e-07 30.7 1.3 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat FYVE PF01363.21 KFP19166.1 - 2.4e-14 53.2 7.8 5.3e-14 52.1 7.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger ANAPC4_WD40 PF12894.7 KFP19166.1 - 2.5e-06 27.7 0.1 0.2 11.9 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP19166.1 - 3.7e-05 22.7 0.2 0.39 9.4 0.0 3.2 3 2 0 3 3 3 2 Nup133 N terminal like FYVE_2 PF02318.16 KFP19166.1 - 0.044 14.0 4.3 0.1 12.8 4.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 KFP19166.1 - 0.11 12.6 7.5 0.9 9.6 7.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF2688 PF10892.8 KFP19166.1 - 0.22 11.0 5.0 0.73 9.3 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2688) DiS_P_DiS PF06750.13 KFP19166.1 - 6.7 6.9 7.3 48 4.2 6.5 2.7 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain adh_short PF00106.25 KFP19168.1 - 1.5e-27 96.3 0.6 1.9e-26 92.7 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP19168.1 - 3.1e-19 69.5 0.1 3.9e-18 65.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP19168.1 - 1.2e-10 41.7 0.1 1.9e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFP19168.1 - 1.1e-07 31.6 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFP19168.1 - 6.4e-05 22.5 0.0 9.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KFP19168.1 - 0.00015 21.3 0.1 0.0077 15.6 0.0 2.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFP19168.1 - 0.00058 19.8 1.5 0.0023 17.9 0.9 2.3 1 1 1 2 2 2 1 NAD(P)H-binding LDcluster4 PF18306.1 KFP19168.1 - 0.0083 15.7 0.2 0.027 14.1 0.2 1.7 2 0 0 2 2 2 1 SLOG cluster4 family Polysacc_synt_2 PF02719.15 KFP19168.1 - 0.055 12.6 0.2 0.083 12.0 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HMA PF00403.26 KFP19169.1 - 9.8e-72 237.3 1.1 6.3e-14 52.2 0.0 6.8 6 0 0 6 6 6 6 Heavy-metal-associated domain Hydrolase PF00702.26 KFP19169.1 - 4.5e-62 210.1 0.7 8.2e-62 209.2 0.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFP19169.1 - 4.5e-46 156.7 4.1 4.5e-46 156.7 4.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP19169.1 - 2.5e-07 30.7 2.6 4.4e-05 23.3 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KFP19169.1 - 0.00023 21.2 0.8 0.01 15.9 0.1 3.2 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP19169.1 - 0.0031 17.6 0.1 0.0086 16.2 0.1 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 KFP19169.1 - 0.011 15.7 0.0 1.9 8.5 0.0 3.7 4 0 0 4 4 4 0 RNA binding motif SapB_2 PF03489.17 KFP19169.1 - 0.026 14.6 0.3 0.083 13.0 0.3 2.0 1 0 0 1 1 1 0 Saposin-like type B, region 2 HAD PF12710.7 KFP19169.1 - 0.029 14.8 0.1 0.061 13.7 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CT_C_D PF02682.16 KFP19169.1 - 0.13 11.9 0.0 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Carboxyltransferase domain, subdomain C and D DUF2200 PF09966.9 KFP19169.1 - 0.78 9.9 4.1 19 5.5 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) GFA PF04828.14 KFP19169.1 - 4.6 7.6 8.8 27 5.2 0.0 4.3 5 0 0 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme 7TM_GPCR_Srh PF10318.9 KFP19169.1 - 4.7 6.2 14.0 8.2 5.4 2.1 2.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh Pkinase PF00069.25 KFP19171.1 - 2.2e-66 223.9 0.2 2.2e-66 223.9 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19171.1 - 1.1e-45 156.0 0.1 2.1e-45 155.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19171.1 - 5.5e-06 25.9 0.1 9e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP19171.1 - 3.8e-05 22.6 0.0 9e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PAP_central PF04928.17 KFP19171.1 - 0.3 10.0 1.1 0.74 8.7 1.1 1.6 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF2439 PF10382.9 KFP19171.1 - 0.61 10.4 3.9 3.9 7.9 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Pkinase PF00069.25 KFP19172.1 - 1.3e-66 224.7 0.1 2.4e-66 223.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19172.1 - 3.5e-45 154.3 0.0 6.8e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19172.1 - 4.2e-08 32.9 0.1 6.1e-07 29.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KFP19172.1 - 0.0029 17.6 0.0 1.3 8.9 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family ALS2CR8 PF15299.6 KFP19172.1 - 0.0059 16.5 0.7 0.0096 15.8 0.7 1.3 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 LPD24 PF18839.1 KFP19172.1 - 0.12 12.7 0.5 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 CKAP2_C PF15297.6 KFP19173.1 - 5.7e-74 249.3 29.7 6.6e-49 166.9 3.7 3.3 2 2 1 3 3 3 2 Cytoskeleton-associated protein 2 C-terminus DNA_ligase_A_N PF04675.14 KFP19173.1 - 0.019 15.3 0.6 0.019 15.3 0.6 2.9 2 1 0 3 3 3 0 DNA ligase N terminus PBECR3 PF18812.1 KFP19173.1 - 0.029 14.3 10.3 0.026 14.5 5.0 2.6 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 EAP30 PF04157.16 KFP19174.1 - 1.1e-42 145.9 0.8 1.6e-42 145.4 0.8 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KFP19174.1 - 2.8e-07 30.6 0.0 5.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KFP19174.1 - 0.0036 17.2 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 GRAM domain TssO PF17561.2 KFP19174.1 - 0.037 14.1 1.2 0.064 13.4 1.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF1351 PF07083.11 KFP19174.1 - 0.039 13.7 2.7 0.066 13.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) PH_TFIIH PF08567.11 KFP19174.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain TTRAP PF14203.6 KFP19174.1 - 0.14 12.1 4.6 0.2 11.7 1.9 2.2 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein SpmSyn_N PF17950.1 KFP19174.1 - 0.19 11.9 0.7 3.8 7.7 0.0 2.7 2 1 1 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal YtxH PF12732.7 KFP19174.1 - 4.2 8.0 8.4 2.6 8.6 5.3 2.1 2 0 0 2 2 2 0 YtxH-like protein TSP_1 PF00090.19 KFP19175.1 - 2.4e-10 40.5 9.4 9.8e-10 38.5 9.4 2.2 1 0 0 1 1 1 1 Thrombospondin type 1 domain AJAP1_PANP_C PF15298.6 KFP19175.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Fibrinogen_C PF00147.18 KFP19176.1 - 1.3e-55 188.7 9.4 1.4e-55 188.5 9.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain KASH PF10541.9 KFP19177.1 - 0.029 14.7 0.8 0.041 14.1 0.8 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain PTEN_C2 PF10409.9 KFP19179.1 - 5.6e-25 87.7 0.1 1.2e-24 86.6 0.1 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Ion_trans PF00520.31 KFP19179.1 - 2.7e-13 49.7 6.3 4e-13 49.2 6.3 1.3 1 0 0 1 1 1 1 Ion transport protein DSPc PF00782.20 KFP19179.1 - 3.4e-09 36.6 0.0 9.3e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP19179.1 - 1.6e-05 25.1 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP19179.1 - 0.0001 21.9 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PKD_channel PF08016.12 KFP19179.1 - 0.0062 15.3 4.3 0.011 14.5 4.3 1.4 1 0 0 1 1 1 1 Polycystin cation channel Y_phosphatase3 PF13350.6 KFP19179.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2162 PF09930.9 KFP19179.1 - 0.33 10.3 3.2 0.51 9.7 3.2 1.2 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF4282 PF14110.6 KFP19179.1 - 1.7 9.5 9.0 0.12 13.1 3.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) Mito_carr PF00153.27 KFP19180.1 - 1.4e-58 194.8 6.2 2.3e-19 69.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fibrillarin PF01269.17 KFP19180.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin MRP-S31 PF15433.6 KFP19181.1 - 2.1e-70 237.9 7.2 2.3e-70 237.8 7.2 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 FOXO_KIX_bdg PF16675.5 KFP19182.1 - 3.1e-30 104.3 2.3 3.1e-30 104.3 2.3 2.8 2 0 0 2 2 2 1 KIX-binding domain of forkhead box O, CR2 FOXO-TAD PF16676.5 KFP19182.1 - 6.5e-21 74.5 8.6 1.4e-20 73.4 8.6 1.6 1 0 0 1 1 1 1 Transactivation domain of FOXO protein family Forkhead PF00250.18 KFP19182.1 - 2.2e-08 34.3 0.2 4.9e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain COG6 PF06419.11 KFP19183.1 - 3e-211 703.0 10.8 3.4e-211 702.8 10.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 KFP19183.1 - 0.0054 16.6 1.6 0.017 15.0 1.6 1.9 1 0 0 1 1 1 1 Sec34-like family YabA PF06156.13 KFP19183.1 - 0.0067 17.0 1.2 0.03 14.9 1.2 2.2 1 0 0 1 1 1 1 Initiation control protein YabA SOGA PF11365.8 KFP19183.1 - 0.024 15.8 3.8 0.033 15.3 1.5 2.5 2 0 0 2 2 2 0 Protein SOGA Jnk-SapK_ap_N PF09744.9 KFP19183.1 - 0.032 14.5 3.0 0.11 12.7 3.0 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Takusan PF04822.13 KFP19183.1 - 0.089 12.7 2.1 0.16 11.9 0.5 2.3 2 0 0 2 2 2 0 Takusan Mod_r PF07200.13 KFP19183.1 - 0.33 11.0 9.5 13 5.8 4.7 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.9 KFP19183.1 - 0.48 10.8 5.8 0.2 12.0 2.1 2.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1043 PF06295.12 KFP19183.1 - 0.65 10.0 3.7 0.7 9.9 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Nup54 PF13874.6 KFP19183.1 - 0.73 9.9 4.3 0.68 10.0 1.4 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GLTSCR1 PF15249.6 KFP19183.1 - 0.82 10.2 4.0 0.75 10.3 1.5 2.1 1 1 1 2 2 2 0 Conserved region of unknown function on GLTSCR protein Syntaxin-6_N PF09177.11 KFP19183.1 - 1.2 9.8 4.3 20 5.8 2.4 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal L_HMGIC_fpl PF10242.9 KFP19184.1 - 6.7e-30 104.6 3.4 7.5e-30 104.5 3.4 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein UPF0016 PF01169.19 KFP19184.1 - 0.31 11.4 5.2 0.075 13.4 1.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 RTP1_C1 PF10363.9 KFP19187.1 - 1.3e-16 60.8 0.1 3.1e-15 56.3 0.0 3.1 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KFP19187.1 - 1.2e-10 40.9 1.6 1.2e-10 40.9 1.6 2.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 KFP19187.1 - 0.00036 20.5 2.5 5.1 7.6 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFP19187.1 - 0.00041 20.7 4.8 0.072 13.5 0.4 3.6 4 0 0 4 4 4 2 HEAT repeats Ctf8 PF09696.10 KFP19188.1 - 4.4e-09 36.8 0.1 6e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Ctf8 ANAPC4_WD40 PF12894.7 KFP19189.1 - 0.0096 16.2 0.3 0.37 11.1 0.1 2.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP19189.1 - 0.045 14.6 11.0 5 8.2 0.1 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat AAA PF00004.29 KFP19190.1 - 1.5e-30 106.3 0.0 2.9e-30 105.4 0.0 1.4 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KFP19190.1 - 1.5e-06 27.7 0.0 2.1e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KFP19190.1 - 1.9e-06 28.2 0.1 0.00043 20.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP19190.1 - 2.2e-06 28.2 0.1 0.00093 19.6 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KFP19190.1 - 2.6e-06 27.3 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFP19190.1 - 1.6e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFP19190.1 - 2.5e-05 24.3 0.0 7.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFP19190.1 - 2.5e-05 24.1 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KFP19190.1 - 3.4e-05 23.5 0.1 0.23 11.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KFP19190.1 - 9.2e-05 21.7 0.0 0.00013 21.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFP19190.1 - 0.00015 22.3 0.0 0.00032 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFP19190.1 - 0.00031 20.9 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFP19190.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KFP19190.1 - 0.0019 17.6 0.0 0.88 9.0 0.0 2.4 2 1 1 3 3 2 1 Bacterial TniB protein ATPase PF06745.13 KFP19190.1 - 0.0031 16.9 0.1 1.5 8.1 0.0 2.2 1 1 1 2 2 2 2 KaiC RNA_helicase PF00910.22 KFP19190.1 - 0.0035 17.7 0.0 0.0056 17.0 0.0 1.6 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 KFP19190.1 - 0.0038 17.1 0.0 0.082 12.8 0.0 2.1 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.6 KFP19190.1 - 0.0044 16.8 0.0 0.0072 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFP19190.1 - 0.0063 16.1 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 KFP19190.1 - 0.0074 16.7 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFP19190.1 - 0.0082 15.5 0.2 0.02 14.3 0.0 1.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFP19190.1 - 0.0084 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Sigma54_activat PF00158.26 KFP19190.1 - 0.012 15.3 0.0 0.05 13.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KFP19190.1 - 0.012 15.5 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KFP19190.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFP19190.1 - 0.034 13.9 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 KFP19190.1 - 0.035 13.2 0.0 0.061 12.4 0.0 1.4 2 0 0 2 2 1 0 MCM P-loop domain EF-1_beta_acid PF10587.9 KFP19190.1 - 0.037 14.5 3.8 0.49 10.9 0.1 2.7 3 0 0 3 3 2 0 Eukaryotic elongation factor 1 beta central acidic region AFG1_ATPase PF03969.16 KFP19190.1 - 0.05 12.5 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFP19190.1 - 0.069 12.4 0.1 0.58 9.4 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 KFP19190.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFP19190.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KFP19190.1 - 0.077 12.7 0.0 0.32 10.6 0.0 1.9 1 1 0 2 2 2 0 Guanylate kinase ResIII PF04851.15 KFP19190.1 - 0.084 12.9 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 KFP19190.1 - 0.085 12.1 0.0 0.22 10.7 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 KFP19190.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFP19190.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KFP19190.1 - 0.14 12.2 0.0 2.5 8.2 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFP19190.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KFP19190.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin EMP24_GP25L PF01105.24 KFP19192.1 - 1.6e-23 83.6 0.3 1.9e-23 83.3 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4304 PF14137.6 KFP19192.1 - 0.0082 16.3 1.0 0.013 15.7 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4304) TERF2_RBM PF16772.5 KFP19193.1 - 7.2e-23 79.7 0.3 1.4e-22 78.9 0.3 1.5 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif TRF PF08558.10 KFP19193.1 - 1.1e-22 80.9 1.2 2e-22 80.0 1.2 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KFP19193.1 - 5.7e-11 42.4 1.8 5.7e-11 42.4 1.8 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP19193.1 - 0.022 15.0 1.2 0.022 15.0 1.2 2.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain Ribosomal_L36e PF01158.18 KFP19193.1 - 0.25 11.6 3.8 0.77 10.0 3.8 1.8 1 0 0 1 1 1 0 Ribosomal protein L36e NOB1_Zn_bind PF08772.11 KFP19194.1 - 8.1e-23 80.4 0.1 1.5e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like WRNPLPNID PF15017.6 KFP19194.1 - 4e-19 69.3 8.2 6.7e-19 68.5 8.2 1.4 1 0 0 1 1 1 1 Putative WW-binding domain and destruction box Peptidase_C31 PF05410.13 KFP19194.1 - 0.064 13.3 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha zinc_ribbon_2 PF13240.6 KFP19194.1 - 0.079 12.7 0.5 0.16 11.7 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Cys_rich_KTR PF14205.6 KFP19194.1 - 0.14 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR zinc_ribbon_9 PF14369.6 KFP19194.1 - 0.27 11.5 1.0 0.69 10.2 1.0 1.7 1 0 0 1 1 1 0 zinc-ribbon HECT PF00632.25 KFP19195.1 - 1.2e-80 271.3 0.3 6e-80 269.0 0.3 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFP19195.1 - 1.5e-44 149.8 34.0 1.5e-13 50.5 4.8 4.6 4 0 0 4 4 4 4 WW domain MitMem_reg PF13012.6 KFP19196.1 - 3.2e-36 124.2 0.5 5.3e-36 123.4 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFP19196.1 - 1.2e-25 89.8 1.8 1.7e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Coilin_N PF15862.5 KFP19196.1 - 0.003 17.4 8.6 0.0051 16.6 8.6 1.3 1 0 0 1 1 1 1 Coilin N-terminus Connexin PF00029.19 KFP19196.1 - 0.027 14.2 5.6 0.048 13.4 5.6 1.3 1 0 0 1 1 1 0 Connexin PAS_3 PF08447.12 KFP19197.1 - 2.4e-24 85.4 0.0 1.6e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP19197.1 - 1.9e-22 79.5 0.5 6.4e-20 71.4 0.4 2.8 2 1 1 3 3 3 1 PAS domain PAS PF00989.25 KFP19197.1 - 3.7e-21 75.2 0.1 4.9e-13 49.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold HLH PF00010.26 KFP19197.1 - 2.9e-14 52.8 1.5 1.5e-13 50.5 1.3 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP19197.1 - 4.4e-10 39.7 0.0 5.3e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFP19197.1 - 0.00085 19.6 0.0 0.78 10.0 0.0 2.7 2 0 0 2 2 2 2 PAS fold HAUS2 PF15003.6 KFP19197.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF5604 PF18300.1 KFP19198.1 - 2.2e-18 65.9 1.1 3.9e-18 65.2 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5604) DUF948 PF06103.11 KFP19198.1 - 0.0022 18.2 1.0 1.2 9.5 0.0 2.7 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 KFP19198.1 - 0.06 13.0 16.0 0.081 12.6 11.0 2.3 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein PIN_3 PF13470.6 KFP19198.1 - 0.063 14.0 1.8 0.17 12.6 1.8 1.7 1 0 0 1 1 1 0 PIN domain P4Ha_N PF08336.11 KFP19198.1 - 0.078 13.0 3.2 0.95 9.5 0.5 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2203 PF09969.9 KFP19198.1 - 0.27 12.0 6.2 0.84 10.4 2.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3391 PF11871.8 KFP19198.1 - 0.39 11.3 8.5 3.4 8.2 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) Laminin_II PF06009.12 KFP19198.1 - 0.43 10.6 7.0 0.14 12.2 1.6 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4164 PF13747.6 KFP19198.1 - 0.48 10.7 7.4 0.55 10.5 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Phytochelatin PF05023.14 KFP19198.1 - 0.59 9.3 3.1 0.43 9.8 0.7 1.8 2 0 0 2 2 2 0 Phytochelatin synthase BLOC1_2 PF10046.9 KFP19198.1 - 1.3 9.4 9.9 5.5 7.4 3.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 KFP19198.1 - 1.8 8.8 11.0 3.3 8.0 11.0 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4446 PF14584.6 KFP19198.1 - 2.3 8.2 5.5 19 5.2 3.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 KFP19198.1 - 3.6 6.7 5.9 3.4 6.8 3.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein Spc24 PF08286.11 KFP19198.1 - 4.1 7.7 10.2 3 8.2 6.0 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 P16-Arc PF04699.14 KFP19199.1 - 5e-48 163.4 0.1 5.4e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KFP19199.1 - 0.0045 17.3 0.0 0.0062 16.8 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family SH3_1 PF00018.28 KFP19200.1 - 4.1e-28 96.7 0.1 1.3e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP19200.1 - 5.4e-24 83.8 0.1 3.4e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KFP19200.1 - 3.3e-17 61.9 0.0 9.3e-11 41.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain TPR_1 PF00515.28 KFP19200.1 - 2.8e-15 55.4 5.6 1.1e-05 25.0 0.2 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19200.1 - 1.6e-13 49.7 2.3 0.00038 20.3 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.24 KFP19200.1 - 3.7e-09 36.4 0.0 7.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 KFP19200.1 - 3.9e-09 36.7 1.7 0.00028 21.1 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19200.1 - 4.3e-09 35.9 4.0 0.08 13.2 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19200.1 - 2.5e-07 30.2 0.5 0.012 15.5 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19200.1 - 1.7e-05 25.4 0.1 0.002 18.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19200.1 - 6.7e-05 23.0 0.1 0.72 10.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP19200.1 - 6.8e-05 22.6 0.8 8.3 6.4 0.2 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19200.1 - 0.0022 18.7 0.3 1.5 9.9 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP19200.1 - 0.0052 16.9 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP19200.1 - 0.0083 16.7 1.3 5.3 7.9 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP19200.1 - 0.0097 15.6 1.8 0.085 12.6 0.1 3.1 2 1 1 3 3 3 1 TPR repeat Cohesin_load PF10345.9 KFP19200.1 - 0.02 13.4 0.9 0.029 12.8 0.9 1.1 1 0 0 1 1 1 0 Cohesin loading factor Cobl PF09469.10 KFP19200.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain RBD PF02196.15 KFP19200.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain TPR_19 PF14559.6 KFP19200.1 - 0.32 11.5 2.6 17 6.0 1.4 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 KFP19201.1 - 1e-55 189.2 4.7 1e-55 189.2 4.7 2.4 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KFP19201.1 - 4.5e-25 88.9 0.3 4.5e-25 88.9 0.3 2.6 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf-AD PF07776.15 KFP19201.1 - 0.0046 17.2 0.6 0.02 15.1 0.6 2.2 1 1 0 1 1 1 1 Zinc-finger associated domain (zf-AD) TPR_2 PF07719.17 KFP19201.1 - 0.054 13.6 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19201.1 - 0.062 13.3 0.6 0.26 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19201.1 - 0.23 11.9 1.1 0.67 10.5 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_transf_like PF01467.26 KFP19202.1 - 5.8e-16 59.0 0.0 1.1e-14 54.8 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like Laminin_EGF PF00053.24 KFP19203.1 - 3.5e-38 129.5 156.5 1.5e-09 37.8 11.4 8.6 8 0 0 8 8 8 7 Laminin EGF domain Laminin_B PF00052.18 KFP19203.1 - 1.1e-28 99.8 0.0 7.2e-28 97.2 0.0 2.3 2 0 0 2 2 2 1 Laminin B (Domain IV) Spc7 PF08317.11 KFP19203.1 - 3.4e-05 22.9 13.1 3.4e-05 22.9 13.1 4.0 2 1 1 3 3 3 1 Spc7 kinetochore protein XhlA PF10779.9 KFP19203.1 - 0.37 11.0 14.8 0.78 10.0 2.1 4.6 4 0 0 4 4 4 0 Haemolysin XhlA DUF2730 PF10805.8 KFP19203.1 - 1.7 8.8 5.6 1.7 8.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) ADIP PF11559.8 KFP19203.1 - 1.9 8.6 26.3 1.5 8.9 1.2 4.4 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding AKNA PF12443.8 KFP19203.1 - 4.1 8.1 8.8 0.24 12.1 1.2 2.8 3 0 0 3 3 3 0 AT-hook-containing transcription factor OB_NTP_bind PF07717.16 KFP19204.1 - 4.4e-14 52.6 0.0 8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold dsrm PF00035.26 KFP19205.1 - 1.7e-18 67.1 0.3 1.9e-11 44.5 0.2 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.31 KFP19205.1 - 9.7e-16 58.1 0.0 3e-15 56.5 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP19205.1 - 2.3e-07 30.8 0.0 8.6e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 KFP19205.1 - 2.6e-05 24.4 0.4 7.3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) ResIII PF04851.15 KFP19205.1 - 0.006 16.6 0.4 0.11 12.5 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KFP19205.1 - 0.011 15.7 0.1 0.068 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFP19205.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Dicer_dimer PF03368.14 KFP19205.1 - 0.018 15.2 0.1 0.14 12.3 0.0 2.5 3 0 0 3 3 3 0 Dicer dimerisation domain ATPase PF06745.13 KFP19205.1 - 0.032 13.6 0.0 0.084 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KFP19205.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KFP19205.1 - 0.075 12.5 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KFP19205.1 - 0.078 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase2 PF18747.1 KFP19205.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 DHDPS PF00701.22 KFP19206.1 - 3.4e-46 157.3 0.0 3.9e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SOUL PF04832.12 KFP19207.1 - 2.1e-47 161.4 0.0 2.6e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein BTB PF00651.31 KFP19208.1 - 6.4e-27 94.0 0.3 1.1e-26 93.3 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP19208.1 - 4.4e-16 58.5 18.0 4.2e-07 30.1 4.1 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFP19208.1 - 3.2e-12 46.2 20.7 2.1e-05 24.7 1.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19208.1 - 2.5e-09 37.2 18.3 0.0042 17.8 1.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3342 PF11822.8 KFP19208.1 - 1.8e-05 24.8 0.1 3.5e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) zf-C2H2_2 PF12756.7 KFP19208.1 - 0.00073 19.8 7.5 0.076 13.4 0.0 3.5 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP19208.1 - 0.0017 18.7 16.6 0.035 14.5 0.7 4.4 5 0 0 5 5 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP19208.1 - 0.0028 17.4 3.7 1.2 8.9 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP19208.1 - 0.011 16.1 9.9 0.11 12.9 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KFP19208.1 - 0.08 13.4 8.9 2.3 8.7 1.2 3.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger BTB_2 PF02214.22 KFP19208.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain PyrI_C PF02748.15 KFP19208.1 - 0.26 11.2 3.4 10 6.1 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFP19208.1 - 0.3 11.8 2.8 1.1 10.1 0.7 2.3 1 1 1 2 2 2 0 zinc-ribbon family zf-Di19 PF05605.12 KFP19208.1 - 0.54 10.6 9.0 0.12 12.6 0.8 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KFP19208.1 - 0.92 9.6 3.3 0.85 9.7 0.6 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 KFP19208.1 - 1.3 9.2 7.0 19 5.5 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf_C2H2_ZHX PF18387.1 KFP19208.1 - 1.6 8.5 9.0 16 5.2 0.2 3.3 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain HNH_5 PF14279.6 KFP19208.1 - 1.9 8.4 5.2 27 4.7 0.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf-trcl PF13451.6 KFP19208.1 - 2.2 8.2 5.6 2.4 8.1 0.2 2.6 2 1 1 3 3 3 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KFP19208.1 - 2.9 7.7 15.7 2.4 8.0 1.0 3.7 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-BED PF02892.15 KFP19208.1 - 3.4 7.8 16.2 4.7 7.3 0.6 3.5 1 1 1 2 2 2 0 BED zinc finger PriA_CRR PF18319.1 KFP19208.1 - 4.3 7.4 7.8 27 4.9 0.9 3.3 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2H2_6 PF13912.6 KFP19208.1 - 4.5 7.4 13.7 0.75 9.9 1.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP19208.1 - 6.2 7.5 8.1 19 5.9 0.7 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats ROQ_II PF18386.1 KFP19209.1 - 2.1e-33 113.9 0.6 4e-33 113.0 0.6 1.5 1 0 0 1 1 1 1 Roquin II domain zf-RING_UBOX PF13445.6 KFP19209.1 - 4.2e-06 26.7 6.7 9.5e-06 25.5 6.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFP19209.1 - 5.1e-06 26.3 6.3 0.00011 22.0 1.6 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP19209.1 - 1.6e-05 24.6 3.8 3.2e-05 23.7 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP19209.1 - 2.7e-05 24.4 6.4 5.4e-05 23.4 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP19209.1 - 3.3e-05 23.9 5.1 7.5e-05 22.8 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP19209.1 - 4e-05 23.5 6.4 8e-05 22.5 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP19209.1 - 0.00017 21.4 7.2 0.00034 20.4 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 KFP19209.1 - 0.00026 20.8 3.0 0.00026 20.8 3.0 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 KFP19209.1 - 0.0016 18.3 7.4 0.0037 17.1 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KFP19209.1 - 0.0019 18.3 1.3 0.0039 17.3 1.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf_CCCH_4 PF18345.1 KFP19209.1 - 0.0073 16.3 2.4 0.023 14.8 2.4 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFP19209.1 - 0.033 14.0 2.0 0.07 13.0 2.0 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger PaaA_PaaC PF05138.12 KFP19209.1 - 0.038 13.2 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF743 PF05332.11 KFP19209.1 - 0.043 13.9 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF743) Baculo_IE-1 PF05290.11 KFP19209.1 - 0.057 13.4 1.5 0.13 12.2 1.5 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 KFP19209.1 - 0.063 13.1 4.9 0.14 12.0 4.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KFP19209.1 - 0.21 11.7 8.0 0.089 12.9 4.1 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KFP19209.1 - 0.24 11.3 1.3 0.49 10.3 1.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KFP19209.1 - 0.57 10.1 2.8 1.6 8.7 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3694 PF12473.8 KFP19210.1 - 1.9e-39 135.8 0.1 4e-39 134.7 0.1 1.6 1 1 0 1 1 1 1 Kinesin protein PID PF00640.23 KFP19210.1 - 0.016 15.2 1.0 0.025 14.6 1.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) 7tm_1 PF00001.21 KFP19211.1 - 1.4e-39 136.1 19.1 2e-39 135.5 19.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP19211.1 - 1.9e-08 34.4 10.1 1.9e-08 34.4 10.1 1.7 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP19211.1 - 2.8e-06 27.2 20.2 2.8e-06 27.2 20.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Orf78 PF06024.12 KFP19211.1 - 1.3 9.3 0.0 1.3 9.3 0.0 2.9 3 1 1 4 4 4 0 Orf78 (ac78) Cpn10 PF00166.21 KFP19212.1 - 8.9e-17 60.9 0.4 9.5e-17 60.9 0.4 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Clat_adaptor_s PF01217.20 KFP19213.1 - 7.3e-59 197.8 3.3 8.3e-59 197.6 3.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Siah-Interact_N PF09032.11 KFP19214.1 - 1.3e-15 57.5 3.4 1.3e-15 57.5 3.4 2.4 2 1 0 2 2 2 1 Siah interacting protein, N terminal CS PF04969.16 KFP19214.1 - 5.4e-15 56.2 2.1 7.2e-15 55.8 0.3 1.9 2 0 0 2 2 2 1 CS domain SGS PF05002.15 KFP19214.1 - 2.7e-06 27.4 2.4 6e-06 26.3 2.4 1.6 1 0 0 1 1 1 1 SGS domain DUF3290 PF11694.8 KFP19214.1 - 0.012 15.6 0.2 0.022 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Pih1_fungal_CS PF18482.1 KFP19214.1 - 0.17 12.5 4.1 0.47 11.0 0.8 2.8 2 1 1 3 3 3 0 Fungal Pih1 CS domain fn3 PF00041.21 KFP19215.1 - 6.7e-80 263.5 16.3 1.2e-15 57.6 0.1 6.4 6 0 0 6 6 6 6 Fibronectin type III domain Fibrinogen_C PF00147.18 KFP19215.1 - 7.9e-79 264.5 5.7 1.3e-78 263.8 5.7 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4998 PF16389.5 KFP19215.1 - 1.8e-13 50.5 2.3 0.029 13.9 0.1 5.4 6 0 0 6 6 6 4 Domain of unknown function EGF_2 PF07974.13 KFP19215.1 - 1.5e-11 44.5 76.0 0.00071 19.9 14.8 4.7 4 1 0 4 4 4 3 EGF-like domain Interfer-bind PF09294.10 KFP19215.1 - 4.2e-09 36.7 0.3 5.1 7.5 0.0 6.3 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFP19215.1 - 1.1e-06 29.1 19.0 0.74 10.4 0.3 7.7 5 3 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain CBM_4_9 PF02018.17 KFP19215.1 - 3.2e-05 24.2 5.9 1.2 9.4 0.0 5.4 4 1 0 6 6 5 2 Carbohydrate binding domain EGF_Tenascin PF18720.1 KFP19215.1 - 0.00019 21.4 12.6 0.00019 21.4 12.6 4.6 4 0 0 4 4 3 2 Tenascin EGF domain fn3_2 PF16893.5 KFP19215.1 - 0.0054 16.8 2.2 12 6.1 0.1 5.0 5 1 0 5 5 5 1 Fibronectin type III domain MotY_N PF18393.1 KFP19215.1 - 0.0067 16.6 0.1 9.8 6.3 0.0 3.4 2 1 1 3 3 3 1 MotY N-terminal domain Glyco_hydro_36C PF16874.5 KFP19215.1 - 0.0074 16.8 0.0 23 5.6 0.0 4.2 4 0 0 4 4 4 0 Glycosyl hydrolase family 36 C-terminal domain TSC22 PF01166.18 KFP19215.1 - 0.046 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family AbiEi_1 PF09407.10 KFP19215.1 - 0.065 13.5 0.1 26 5.1 0.0 3.1 3 0 0 3 3 3 0 AbiEi antitoxin C-terminal domain DUF1541 PF07563.11 KFP19215.1 - 0.37 10.7 4.3 24 4.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1541) WD40 PF00400.32 KFP19216.1 - 1.3e-22 79.6 4.4 0.032 15.1 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 KFP19216.1 - 7.2e-15 54.6 7.8 1.8e-14 53.3 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP19216.1 - 2.2e-09 37.0 8.6 6.5e-09 35.5 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP19216.1 - 2.5e-07 30.6 4.1 9e-07 28.8 4.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP19216.1 - 2.6e-07 30.5 7.4 2.6e-07 30.5 7.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP19216.1 - 5.3e-07 29.4 5.5 1.4e-06 28.1 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP19216.1 - 5.4e-07 29.8 7.1 5.4e-07 29.8 7.1 2.8 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP19216.1 - 7.1e-06 26.1 7.5 2.6e-05 24.3 7.5 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFP19216.1 - 9.2e-05 22.7 3.7 9.2e-05 22.7 3.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain ANAPC4_WD40 PF12894.7 KFP19216.1 - 0.00014 22.1 0.4 1.6 9.1 0.0 4.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP19216.1 - 0.0003 20.2 0.0 0.0018 17.7 0.0 2.1 1 1 1 2 2 2 1 WD40-like domain zf-RING_4 PF14570.6 KFP19216.1 - 0.0057 16.4 7.1 0.015 15.1 7.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFP19216.1 - 0.0064 16.3 5.2 0.017 15.0 5.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_C2H2_10 PF18414.1 KFP19216.1 - 0.041 13.4 0.1 0.13 11.8 0.1 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-RING_10 PF16685.5 KFP19216.1 - 0.05 13.7 2.2 0.17 12.1 2.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 AAA_23 PF13476.6 KFP19216.1 - 7.4 7.0 6.8 16 6.0 6.8 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M43 PF05572.13 KFP19217.1 - 8.9e-12 45.2 0.3 8.9e-12 45.2 0.3 2.1 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Sushi PF00084.20 KFP19217.1 - 1.3e-09 38.5 58.1 2.1e-06 28.3 1.5 8.5 8 1 1 9 9 9 4 Sushi repeat (SCR repeat) Notch PF00066.17 KFP19217.1 - 3.2e-05 24.3 1.3 3.2e-05 24.3 1.3 6.6 6 1 0 6 6 6 3 LNR domain DUF4215 PF13948.6 KFP19217.1 - 0.00017 22.0 2.4 0.00017 22.0 2.4 6.7 8 0 0 8 8 8 1 Domain of unknown function (DUF4215) Reprolysin_3 PF13582.6 KFP19217.1 - 0.0038 17.7 0.2 0.0081 16.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFP19217.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-zincin fn3 PF00041.21 KFP19217.1 - 0.14 12.6 0.2 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Fibronectin type III domain Peptidase_M66 PF10462.9 KFP19217.1 - 0.3 10.0 1.8 0.58 9.0 1.8 1.4 1 0 0 1 1 1 0 Peptidase M66 Annexin_like PF18411.1 KFP19218.1 - 1.1e-49 166.6 0.0 2.4e-49 165.6 0.0 1.6 1 0 0 1 1 1 1 Annexin-like domain FXa_inhibition PF14670.6 KFP19218.1 - 5.2e-12 45.8 33.4 2.4e-09 37.3 3.2 4.0 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site MACPF PF01823.19 KFP19218.1 - 0.00041 20.5 0.3 0.0019 18.4 0.1 2.0 2 0 0 2 2 2 1 MAC/Perforin domain ASTN_2_hairpin PF18577.1 KFP19218.1 - 0.00069 19.7 0.1 0.0017 18.4 0.1 1.7 1 0 0 1 1 1 1 Astrotactin-2 C-terminal beta-hairpin domain Tme5_EGF_like PF09064.10 KFP19218.1 - 0.0021 17.9 1.2 0.0021 17.9 1.2 3.0 3 0 0 3 3 3 1 Thrombomodulin like fifth domain, EGF-like UPF0560 PF10577.9 KFP19218.1 - 0.073 11.6 0.4 0.14 10.6 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2369 PF10179.9 KFP19218.1 - 0.087 13.2 0.1 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) MACPF PF01823.19 KFP19219.1 - 6.5e-06 26.4 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain OGG_N PF07934.12 KFP19219.1 - 0.0033 17.5 2.0 16 5.6 0.0 3.9 4 0 0 4 4 4 2 8-oxoguanine DNA glycosylase, N-terminal domain Sec16_C PF12931.7 KFP19220.1 - 4.8e-44 151.2 0.0 1.5e-43 149.6 0.0 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFP19220.1 - 5.2e-07 30.3 0.0 1.6e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region 7tm_4 PF13853.6 KFP19221.1 - 1.4e-50 172.6 9.1 1.6e-50 172.4 9.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19221.1 - 8.7e-31 107.2 12.7 1.2e-30 106.8 12.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP19221.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal 7tm_1 PF00001.21 KFP19222.1 - 1.5e-48 165.4 13.0 1.9e-48 165.1 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OapA_N PF08525.11 KFP19222.1 - 0.26 11.3 3.4 0.85 9.6 3.4 1.9 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Chordopox_G3 PF06129.12 KFP19222.1 - 3.6 8.3 6.1 0.54 11.0 1.1 2.3 3 0 0 3 3 3 0 Chordopoxvirus G3 protein DUF4131 PF13567.6 KFP19222.1 - 9.6 5.8 7.4 2.2 7.9 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UBA PF00627.31 KFP19223.1 - 4.1e-12 45.7 0.6 7.4e-12 44.9 0.6 1.5 1 0 0 1 1 1 1 UBA/TS-N domain 7tm_1 PF00001.21 KFP19224.1 - 1.5e-34 119.6 23.6 2e-34 119.1 23.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP19224.1 - 0.0057 16.3 32.0 0.021 14.5 30.2 2.4 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Ni_hydr_CYTB PF01292.20 KFP19224.1 - 4.2 6.9 9.4 86 2.7 9.5 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DHR-2 PF06920.13 KFP19225.1 - 4.2e-211 702.2 7.4 4.2e-211 702.2 7.4 2.0 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 KFP19225.1 - 3.4e-58 196.7 0.4 1.1e-57 195.0 0.4 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KFP19225.1 - 1.9e-41 141.0 0.8 6.9e-41 139.2 0.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 KFP19225.1 - 4e-14 53.0 0.3 1.5e-13 51.2 0.3 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KFP19225.1 - 3.5e-05 24.1 0.0 0.00018 21.8 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFP19225.1 - 0.029 14.6 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PTR2 PF00854.21 KFP19226.1 - 6.3e-53 180.0 0.4 8.4e-53 179.6 0.4 1.1 1 0 0 1 1 1 1 POT family MFS_2 PF13347.6 KFP19226.1 - 6.8e-08 31.5 1.1 4.9e-06 25.4 1.4 1.8 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KFP19226.1 - 2.9e-06 26.4 3.0 8.3e-06 24.9 2.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily EI24 PF07264.11 KFP19226.1 - 0.083 13.1 1.6 0.24 11.6 1.6 1.9 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) RhoGEF PF00621.20 KFP19227.1 - 1.1e-31 110.5 2.8 2.7e-31 109.2 2.0 2.1 2 0 0 2 2 2 1 RhoGEF domain FERM_C PF09380.10 KFP19227.1 - 1.9e-25 89.1 0.2 5e-25 87.7 0.2 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.29 KFP19227.1 - 4.9e-23 81.7 0.4 1.8e-13 50.9 0.6 3.0 2 0 0 2 2 2 2 PH domain FA PF08736.11 KFP19227.1 - 5.2e-16 58.5 3.0 1.9e-15 56.6 3.0 2.1 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 KFP19227.1 - 6.8e-13 49.0 0.8 2.8e-12 47.1 0.7 2.1 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP19227.1 - 1e-08 35.0 0.0 2.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain IQ_SEC7_PH PF16453.5 KFP19227.1 - 2.5e-06 27.5 0.0 7.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KFP19227.1 - 0.00029 20.7 2.9 0.52 10.1 0.0 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KFP19227.1 - 0.095 13.1 5.5 0.79 10.2 1.3 4.0 3 1 0 3 3 3 0 Pleckstrin homology domain PH_2 PF08458.10 KFP19227.1 - 0.13 12.6 0.3 43 4.5 0.0 3.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region HEAT PF02985.22 KFP19228.1 - 2.3e-19 67.8 0.2 3.4e-05 23.7 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KFP19228.1 - 1.7e-18 66.7 0.3 7e-09 36.0 0.0 5.4 7 0 0 7 7 6 2 HEAT-like repeat Importin_rep_4 PF18808.1 KFP19228.1 - 5.8e-16 58.6 1.2 5.8e-16 58.6 1.2 3.2 2 0 0 2 2 2 1 Importin repeat HEAT_2 PF13646.6 KFP19228.1 - 9.2e-15 54.8 0.0 1.2e-08 35.2 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP19228.1 - 1.9e-12 47.6 1.7 1.4e-06 28.8 0.0 6.1 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 KFP19228.1 - 5.7e-11 42.5 2.4 2e-10 40.8 0.1 2.9 3 0 0 3 3 3 1 Importin repeat 6 Cnd1 PF12717.7 KFP19228.1 - 5.6e-08 33.0 0.0 0.00053 20.1 0.1 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KFP19228.1 - 1.4e-07 31.6 0.1 0.57 10.1 0.3 6.6 5 1 2 7 7 7 1 Domain of unknown function (DUF3385) Importin_rep_5 PF18816.1 KFP19228.1 - 0.00089 19.5 0.1 0.037 14.3 0.0 2.6 2 0 0 2 2 2 1 Importin repeat Adaptin_N PF01602.20 KFP19228.1 - 0.0012 17.5 0.5 0.0063 15.1 0.3 2.2 2 1 0 2 2 2 1 Adaptin N terminal region Arm PF00514.23 KFP19228.1 - 0.0024 17.9 2.5 5.9 7.1 0.0 4.8 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFP19228.1 - 0.0079 16.4 0.3 0.96 9.7 0.0 3.9 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 PBP1_TM PF14812.6 KFP19228.1 - 0.016 15.5 0.1 0.016 15.5 0.1 2.2 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HEAT_PBS PF03130.16 KFP19228.1 - 0.065 13.9 0.9 24 6.0 0.0 4.1 4 1 1 5 5 3 0 PBS lyase HEAT-like repeat AbiJ_NTD5 PF18865.1 KFP19228.1 - 0.089 12.6 0.2 0.7 9.7 0.5 2.4 3 0 0 3 3 2 0 AbiJ N-terminal domain 5 Rad52_Rad22 PF04098.15 KFP19229.1 - 1.5e-48 164.6 0.0 1.5e-48 164.6 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein PAP_central PF04928.17 KFP19229.1 - 0.095 11.7 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain Pkinase PF00069.25 KFP19230.1 - 2.6e-53 181.1 0.0 3.9e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19230.1 - 4.3e-41 140.9 0.0 6.4e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFP19230.1 - 2e-30 104.8 3.9 2.2e-26 91.8 0.3 2.5 2 0 0 2 2 2 2 Oxidative-stress-responsive kinase 1 C-terminal domain CHGN PF05679.16 KFP19232.1 - 2.7e-24 85.9 0.1 9.8e-24 84.0 0.1 1.8 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 KFP19232.1 - 2.5e-12 46.3 0.7 5.5e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase PA14 PF07691.12 KFP19232.1 - 3.3e-08 33.4 0.0 6.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KFP19232.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 GLEYA domain Atg14 PF10186.9 KFP19234.1 - 0.093 11.8 46.2 0.029 13.4 12.9 3.5 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_lysozyme PF00959.19 KFP19234.1 - 0.29 11.6 3.0 13 6.3 0.5 2.9 2 1 1 3 3 3 0 Phage lysozyme Fez1 PF06818.15 KFP19234.1 - 4.7 7.6 46.1 0.83 10.1 19.7 3.9 2 1 2 4 4 4 0 Fez1 PLU-1 PF08429.11 KFP19235.1 - 2e-101 339.5 10.7 2e-101 339.5 10.7 4.4 4 1 0 4 4 4 2 PLU-1-like protein JmjC PF02373.22 KFP19235.1 - 2.3e-46 156.9 1.4 7.2e-46 155.3 1.4 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KFP19235.1 - 2.1e-25 88.4 46.9 2.3e-12 46.6 3.3 3.9 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 KFP19235.1 - 2.3e-19 69.9 0.0 8.5e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KFP19235.1 - 1.7e-14 54.0 12.4 1.7e-14 54.0 12.4 3.4 3 0 0 3 3 3 1 C5HC2 zinc finger FRG1 PF06229.12 KFP19235.1 - 0.039 13.7 11.8 5.7 6.6 0.0 2.8 2 0 0 2 2 2 0 FRG1-like domain PHD_2 PF13831.6 KFP19235.1 - 0.44 10.1 20.0 0.69 9.5 0.5 3.8 3 1 0 3 3 3 0 PHD-finger TadF PF16964.5 KFP19235.1 - 1.4 8.6 6.7 2.9 7.6 2.8 2.6 2 0 0 2 2 2 0 Putative tight adherence pilin protein F SNF PF00209.18 KFP19236.1 - 7.7e-245 813.5 36.9 8.8e-245 813.3 36.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFP19237.1 - 7.5e-245 813.5 36.6 8.6e-245 813.3 36.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KFP19238.1 - 5.3e-228 757.9 40.2 6.1e-228 757.7 40.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Sec7 PF01369.20 KFP19239.1 - 5e-62 208.8 0.0 1.2e-61 207.6 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KFP19239.1 - 1.8e-61 206.2 2.5 2.7e-61 205.6 0.8 2.1 2 0 0 2 2 2 1 PH domain AAA_35 PF14516.6 KFP19239.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IQ PF00612.27 KFP19239.1 - 0.47 10.4 2.7 0.57 10.1 0.3 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif WASH_WAHD PF11945.8 KFP19240.1 - 1.4e-124 415.4 0.4 1.9e-124 414.9 0.4 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex FliD_N PF02465.18 KFP19240.1 - 0.12 13.1 0.3 3.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Arg_decarbox_C PF17944.1 KFP19240.1 - 0.21 12.2 0.6 0.55 10.8 0.1 2.0 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension WH2 PF02205.20 KFP19240.1 - 0.45 10.4 2.7 0.48 10.3 0.2 2.3 2 0 0 2 2 2 0 WH2 motif zf-H2C2_2 PF13465.6 KFP19242.1 - 2.5e-65 214.2 56.7 6.9e-11 42.1 0.5 8.7 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 KFP19242.1 - 5.3e-60 196.7 57.2 6.5e-08 32.6 1.9 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19242.1 - 3.1e-38 127.1 53.3 3.6e-05 24.2 0.9 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP19242.1 - 4.8e-25 87.0 48.9 3e-05 23.9 0.9 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP19242.1 - 2.1e-21 75.7 26.7 0.008 16.4 0.1 8.2 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KFP19242.1 - 1.2e-13 50.4 32.6 0.028 14.0 0.4 8.2 7 1 1 8 8 8 7 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP19242.1 - 5.9e-13 48.7 38.1 0.0011 19.1 2.5 5.6 3 2 3 6 6 6 5 Zinc ribbon domain zf-met PF12874.7 KFP19242.1 - 1e-12 48.0 47.3 0.16 12.4 0.1 8.2 8 0 0 8 8 8 7 Zinc-finger of C2H2 type XPA_N PF01286.18 KFP19242.1 - 4.3e-09 36.3 35.5 0.072 13.1 0.5 8.1 8 0 0 8 8 8 3 XPA protein N-terminal zf-C2H2_11 PF16622.5 KFP19242.1 - 1.4e-08 34.4 38.8 0.19 11.5 0.6 8.1 8 0 0 8 8 8 6 zinc-finger C2H2-type Prok-RING_1 PF14446.6 KFP19242.1 - 2.1e-07 30.8 18.6 8.5 6.4 0.1 8.0 7 1 1 8 8 8 0 Prokaryotic RING finger family 1 CpXC PF14353.6 KFP19242.1 - 3.2e-07 30.4 25.3 0.61 10.1 0.1 7.8 4 2 0 5 5 5 1 CpXC protein zinc_ribbon_15 PF17032.5 KFP19242.1 - 3.5e-07 30.9 28.5 0.057 14.2 4.5 4.1 1 1 3 4 4 4 4 zinc-ribbon family zf-Di19 PF05605.12 KFP19242.1 - 1.9e-06 28.1 30.5 0.011 16.0 1.5 4.9 2 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 KFP19242.1 - 3.9e-06 27.0 28.7 0.11 12.8 0.8 5.8 2 2 4 6 6 6 3 LIM domain zf-LYAR PF08790.11 KFP19242.1 - 7.5e-06 25.7 30.4 0.65 9.9 0.4 8.0 8 0 0 8 8 8 2 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.7 KFP19242.1 - 8e-05 22.5 43.3 0.15 12.1 2.8 6.2 4 2 2 6 6 6 3 Transposase zinc-ribbon domain C1_4 PF07975.12 KFP19242.1 - 9.6e-05 22.5 32.9 0.18 12.0 2.2 6.1 1 1 6 7 7 7 3 TFIIH C1-like domain YhfH PF14149.6 KFP19242.1 - 0.00037 20.4 29.1 3.4 7.7 0.2 7.3 8 0 0 8 8 7 0 YhfH-like protein ADK_lid PF05191.14 KFP19242.1 - 0.00039 20.3 24.5 0.33 11.0 0.4 5.5 4 1 1 5 5 5 4 Adenylate kinase, active site lid DNA_RNApol_7kD PF03604.13 KFP19242.1 - 0.00041 20.0 24.1 5.6 6.7 0.2 7.9 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KFP19242.1 - 0.00043 20.3 27.8 0.36 10.9 1.5 4.9 1 1 5 6 6 6 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYDLN_acid PF09538.10 KFP19242.1 - 0.0011 19.6 23.8 17 6.1 2.9 7.2 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) zf-AN1 PF01428.16 KFP19242.1 - 0.0016 18.6 42.2 6.3 7.1 0.6 8.2 6 2 2 8 8 8 0 AN1-like Zinc finger zf-trcl PF13451.6 KFP19242.1 - 0.0017 18.2 29.1 7.9 6.5 0.1 7.9 8 0 0 8 8 8 0 Probable zinc-ribbon domain zf-ribbon_3 PF13248.6 KFP19242.1 - 0.0017 17.7 28.7 0.48 9.9 0.2 7.6 8 0 0 8 8 8 1 zinc-ribbon domain DUF2072 PF09845.9 KFP19242.1 - 0.0019 18.5 29.4 0.2 11.9 0.3 7.1 6 2 2 8 8 8 1 Zn-ribbon containing protein Zn-C2H2_12 PF18112.1 KFP19242.1 - 0.0024 18.3 23.1 0.31 11.6 0.1 7.3 8 0 0 8 8 7 1 Autophagy receptor zinc finger-C2H2 domain DUF2256 PF10013.9 KFP19242.1 - 0.0031 17.6 23.6 10 6.3 0.1 7.9 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3268 PF11672.8 KFP19242.1 - 0.0053 17.1 21.6 0.95 9.8 0.4 4.8 1 1 1 5 5 5 3 zinc-finger-containing domain TFIIS_C PF01096.18 KFP19242.1 - 0.011 15.5 39.1 1.4 8.8 0.4 8.0 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zinc_ribbon_9 PF14369.6 KFP19242.1 - 0.014 15.6 25.1 6.2 7.2 0.1 7.8 8 0 0 8 8 8 0 zinc-ribbon zf_C2H2_13 PF18508.1 KFP19242.1 - 0.015 14.8 13.1 11 5.7 0.0 6.3 7 0 0 7 7 7 0 Zinc finger domain Zn_ribbon_SprT PF17283.2 KFP19242.1 - 0.02 14.8 0.6 0.02 14.8 0.6 6.5 4 3 2 6 6 6 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KFP19242.1 - 0.024 14.6 33.5 36 4.4 7.4 5.8 1 1 2 3 3 3 0 zinc-ribbons HalOD2 PF18547.1 KFP19242.1 - 0.026 14.4 25.1 0.14 12.1 1.0 6.2 4 2 2 6 6 6 0 Halobacterial output domain 2 zf-H2C2_5 PF13909.6 KFP19242.1 - 0.038 13.7 1.0 0.038 13.7 1.0 10.0 9 4 0 9 9 8 0 C2H2-type zinc-finger domain HNH PF01844.23 KFP19242.1 - 0.058 13.6 33.5 5.1 7.4 0.4 7.9 8 0 0 8 8 8 0 HNH endonuclease Yippee-Mis18 PF03226.14 KFP19242.1 - 0.22 11.7 24.0 8.7 6.6 2.3 5.8 4 2 1 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_recom PF13408.6 KFP19242.1 - 0.23 12.0 31.5 2.7 8.6 0.9 6.5 3 2 1 4 4 4 0 Recombinase zinc beta ribbon domain zf-C2HC_2 PF13913.6 KFP19242.1 - 0.36 10.8 36.9 0.75 9.8 0.2 7.7 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KFP19242.1 - 0.37 11.2 33.3 0.59 10.5 0.4 6.6 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.14 KFP19242.1 - 0.49 10.3 0.1 0.49 10.3 0.1 4.5 5 0 0 5 5 4 0 Rad50 zinc hook motif zf_C2H2_ZHX PF18387.1 KFP19242.1 - 0.58 9.8 30.1 2.5 7.8 0.3 6.4 1 1 7 8 8 8 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KFP19242.1 - 0.64 10.1 42.3 0.8 9.8 1.0 7.6 1 1 6 7 7 7 0 BED zinc finger MBD PF01429.19 KFP19242.1 - 1 9.1 5.6 1.1e+02 2.6 5.4 4.2 1 1 1 2 2 2 0 Methyl-CpG binding domain zf-C2HE PF16278.5 KFP19242.1 - 1.5 9.3 43.2 1.4 9.5 0.7 7.7 2 2 6 8 8 8 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_10 PF18414.1 KFP19242.1 - 1.9 8.1 0.0 1.9 8.1 0.0 4.3 5 0 0 5 5 4 0 C2H2 type zinc-finger zinc_ribbon_4 PF13717.6 KFP19242.1 - 2.7 8.0 37.7 18 5.3 0.1 7.7 6 2 1 7 7 7 0 zinc-ribbon domain Sgf11 PF08209.11 KFP19242.1 - 4 7.1 28.6 5.9 6.6 0.1 7.6 8 0 0 8 8 8 0 Sgf11 (transcriptional regulation protein) BolA PF01722.18 KFP19242.1 - 4.5 7.6 17.8 7.3 6.9 0.1 4.7 2 1 2 4 4 3 0 BolA-like protein GAGA PF09237.11 KFP19242.1 - 4.9 7.0 22.4 4.4 7.2 0.3 5.3 1 1 4 6 6 6 0 GAGA factor zf-C2H2_9 PF16293.5 KFP19242.1 - 9.1 6.2 15.2 16 5.5 0.1 5.2 6 1 1 7 7 5 0 C2H2 type zinc-finger (1 copy) PBP_sp32 PF07222.12 KFP19243.1 - 7.3e-32 110.8 0.6 7.8e-32 110.7 0.6 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 TPR_2 PF07719.17 KFP19244.1 - 8.7e-53 172.2 29.7 5e-06 26.2 0.3 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19244.1 - 3.6e-50 165.8 29.1 2.1e-05 24.2 0.1 11.8 11 1 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.6 KFP19244.1 - 1.4e-43 146.3 30.2 8.9e-09 34.9 0.5 10.7 5 4 6 11 11 11 9 TPR repeat TPR_16 PF13432.6 KFP19244.1 - 4.6e-42 142.4 14.0 1.8e-06 28.5 0.3 7.5 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19244.1 - 1e-41 137.6 20.9 0.00015 21.7 0.0 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19244.1 - 1.9e-38 128.1 21.5 0.00092 19.4 0.2 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19244.1 - 3.4e-38 127.0 16.5 2e-05 25.0 0.4 11.2 3 2 8 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19244.1 - 9.8e-36 121.9 28.4 2.4e-07 30.9 0.0 8.6 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 KFP19244.1 - 3.4e-33 114.0 21.5 2.2e-09 37.7 0.2 8.7 6 3 1 7 7 7 6 Tetratricopeptide repeat DUF1736 PF08409.11 KFP19244.1 - 1.8e-31 107.9 1.5 5e-31 106.5 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_10 PF13374.6 KFP19244.1 - 2.1e-24 84.6 30.7 2.9e-05 23.8 0.2 11.2 10 2 1 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19244.1 - 2.6e-21 74.0 18.8 0.00032 20.5 0.1 10.2 10 1 1 11 11 10 6 Tetratricopeptide repeat TPR_15 PF13429.6 KFP19244.1 - 8e-19 67.9 10.4 1.1e-10 41.3 2.6 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP19244.1 - 7.7e-14 51.6 9.9 0.011 15.9 0.0 6.1 3 1 5 8 8 8 5 Tetratricopeptide repeat TPR_4 PF07721.14 KFP19244.1 - 2.6e-11 43.0 0.0 1.1 10.1 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP19244.1 - 4.1e-11 42.9 15.8 1.6e-06 28.2 0.6 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP19244.1 - 2e-08 34.3 21.5 2 9.2 0.0 9.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP19244.1 - 2.3e-08 33.8 13.4 0.012 15.0 5.7 5.0 1 1 3 4 4 4 3 MalT-like TPR region FAT PF02259.23 KFP19244.1 - 3.2e-08 33.2 6.2 0.002 17.4 0.2 2.8 2 1 1 3 3 3 2 FAT domain TPR_5 PF12688.7 KFP19244.1 - 4.7e-07 30.1 7.5 0.012 15.8 0.3 4.4 2 2 2 4 4 4 2 Tetratrico peptide repeat NARP1 PF12569.8 KFP19244.1 - 2.6e-05 23.3 6.4 0.028 13.3 6.4 3.7 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 KFP19244.1 - 6.7e-05 22.8 6.6 0.0032 17.4 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat ChAPs PF09295.10 KFP19244.1 - 7.8e-05 21.8 0.1 0.0079 15.2 0.1 2.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC5 PF12862.7 KFP19244.1 - 0.0002 21.3 3.9 0.59 10.2 0.0 4.5 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KFP19244.1 - 0.00028 21.1 9.3 1 9.7 0.0 5.7 4 3 4 8 8 7 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFP19244.1 - 0.0021 18.0 19.3 0.16 11.8 0.8 6.5 5 1 1 7 7 6 2 Virulence factor membrane-bound polymerase, C-terminal Coatomer_E PF04733.14 KFP19244.1 - 0.0022 17.5 5.2 1.5 8.1 0.0 3.8 2 1 2 4 4 4 1 Coatomer epsilon subunit BTAD PF03704.17 KFP19244.1 - 0.0023 18.4 11.3 0.091 13.2 3.8 3.3 2 1 0 2 2 2 2 Bacterial transcriptional activator domain Sel1 PF08238.12 KFP19244.1 - 0.0029 18.3 1.7 30 5.5 0.1 5.6 5 1 1 6 6 4 0 Sel1 repeat DUF627 PF04781.12 KFP19244.1 - 0.0037 17.2 5.9 3.6 7.7 0.6 4.9 3 2 1 4 4 4 1 Protein of unknown function (DUF627) PPR PF01535.20 KFP19244.1 - 0.0054 16.9 3.7 16 6.0 0.0 5.4 7 0 0 7 7 3 0 PPR repeat SNAP PF14938.6 KFP19244.1 - 0.0064 15.9 10.9 0.5 9.7 1.2 4.2 2 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP Mad3_BUB1_I PF08311.12 KFP19244.1 - 0.017 15.1 7.7 0.019 14.9 0.0 4.2 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 DUF3856 PF12968.7 KFP19244.1 - 0.026 14.6 2.2 6.6 6.8 0.1 4.6 2 2 2 4 4 4 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 KFP19244.1 - 0.073 13.5 1.6 0.12 12.8 0.4 2.0 2 0 0 2 2 1 0 Alkyl sulfatase dimerisation HTH_Bact PF18768.1 KFP19244.1 - 0.093 12.3 0.1 18 5.0 0.1 3.5 3 1 1 4 4 3 0 Helix-turn-helix bacterial domain Fis1_TPR_C PF14853.6 KFP19244.1 - 0.12 12.5 9.1 12 6.0 0.2 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.9 KFP19244.1 - 0.12 12.5 2.0 16 5.7 0.0 3.9 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region DUF2225 PF09986.9 KFP19244.1 - 0.21 11.3 6.8 7.8 6.2 0.0 4.1 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4919 PF16266.5 KFP19244.1 - 0.24 11.3 1.9 45 3.9 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4919) RPN6_N PF18055.1 KFP19244.1 - 0.27 11.6 2.1 4.2 7.7 0.0 3.5 1 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Vps39_1 PF10366.9 KFP19244.1 - 0.48 10.7 2.9 9.7 6.5 0.0 3.4 2 2 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 DUF4810 PF16068.5 KFP19244.1 - 0.6 10.7 4.3 74 4.0 0.0 4.8 5 1 1 6 6 4 0 Domain of unknown function (DUF4810) IBN_N PF03810.19 KFP19245.1 - 5.8e-19 67.8 0.0 1.1e-16 60.5 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFP19245.1 - 4.5e-09 35.6 3.5 4.5e-09 35.6 3.5 3.0 2 1 0 3 3 3 1 Cse1 DUF1539 PF07560.11 KFP19245.1 - 0.0077 16.3 1.9 0.24 11.5 0.1 3.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) Cwf_Cwc_15 PF04889.12 KFP19245.1 - 0.11 12.2 6.0 0.22 11.2 6.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Xpo1 PF08389.12 KFP19245.1 - 0.11 12.5 11.2 0.078 13.0 0.5 4.3 4 1 0 4 4 4 0 Exportin 1-like protein RTP1_C1 PF10363.9 KFP19245.1 - 0.16 12.1 1.8 4 7.7 0.1 3.6 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5367 PF17329.2 KFP19245.1 - 0.27 11.4 1.4 2.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) BUD22 PF09073.10 KFP19245.1 - 0.3 10.4 4.6 0.62 9.3 4.6 1.4 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 KFP19245.1 - 0.45 11.2 5.2 1.1 10.0 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BSP_II PF05432.11 KFP19245.1 - 1.7 8.3 11.7 2.7 7.6 11.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TT_ORF2 PF02957.15 KFP19245.1 - 2.7 8.9 8.9 5.7 7.9 8.9 1.5 1 0 0 1 1 1 0 TT viral ORF2 HAND PF09110.11 KFP19245.1 - 5.7 7.7 6.6 1.3 9.8 0.6 2.4 2 0 0 2 2 2 0 HAND Caprin-1_C PF12287.8 KFP19246.1 - 8.1e-121 404.2 28.4 8.1e-121 404.2 28.4 3.3 3 1 0 3 3 3 1 Cytoplasmic activation/proliferation-associated protein-1 C term Caprin-1_dimer PF18293.1 KFP19246.1 - 4.1e-38 130.4 0.2 1.1e-37 129.0 0.2 1.8 1 0 0 1 1 1 1 Caprin-1 dimerization domain C1q PF00386.21 KFP19246.1 - 4.2e-33 114.3 0.0 9e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 C1q domain Cornifin PF02389.15 KFP19248.1 - 0.19 12.0 55.1 0.23 11.6 55.1 1.0 1 0 0 1 1 1 0 Cornifin (SPRR) family Keratin PF02422.16 KFP19250.1 - 2.3e-24 84.9 27.6 5.8e-23 80.4 27.6 2.1 1 1 0 1 1 1 1 Keratin Keratin PF02422.16 KFP19251.1 - 3.4e-32 110.0 13.1 3.7e-32 109.9 13.1 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.8 KFP19251.1 - 0.07 13.4 9.5 0.11 12.8 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.16 KFP19252.1 - 9.8e-39 131.0 2.9 1.5e-38 130.3 2.9 1.3 1 0 0 1 1 1 1 Keratin Keratin PF02422.16 KFP19253.1 - 1.5e-37 127.1 5.0 1.5e-37 127.1 5.0 1.7 1 1 1 2 2 2 1 Keratin Keratin PF02422.16 KFP19256.1 - 1.6e-39 133.5 3.7 1.6e-39 133.5 3.7 2.0 1 1 1 2 2 2 2 Keratin Keratin PF02422.16 KFP19257.1 - 1.1e-36 124.4 10.1 2.5e-36 123.2 4.3 2.2 1 1 1 2 2 2 2 Keratin NAD_binding_5 PF07994.12 KFP19259.1 - 1.2e-127 425.8 0.0 1.8e-126 421.9 0.0 1.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFP19259.1 - 1.7e-48 163.4 0.1 2.6e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ELL PF10390.9 KFP19260.1 - 6e-99 331.0 0.0 6e-99 331.0 0.0 2.5 2 1 1 3 3 3 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 KFP19260.1 - 3.9e-34 117.4 13.6 3.9e-34 117.4 13.6 3.0 4 0 0 4 4 4 1 Occludin homology domain TraV PF09676.10 KFP19260.1 - 0.65 11.0 12.2 0.97 10.4 7.4 2.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Seryl_tRNA_N PF02403.22 KFP19260.1 - 5.3 7.3 14.2 0.69 10.2 2.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_1 PF00515.28 KFP19261.1 - 2e-16 59.0 4.3 9.3e-07 28.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19261.1 - 6.3e-14 50.9 2.9 3.6e-06 26.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 KFP19261.1 - 8.2e-14 51.7 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_14 PF13428.6 KFP19261.1 - 1.9e-08 34.4 0.0 3.3e-05 24.3 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19261.1 - 3.1e-08 33.2 0.3 5.2e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP19261.1 - 6.1e-08 32.6 2.4 0.00079 19.5 0.1 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFP19261.1 - 1.3e-07 31.2 0.9 2.4e-05 23.9 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 KFP19261.1 - 1.1e-06 28.2 0.6 0.0055 16.7 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19261.1 - 1.2e-06 28.7 0.4 6e-05 23.3 0.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP19261.1 - 2.4e-06 27.6 0.0 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19261.1 - 2.9e-06 27.8 0.2 0.00063 20.3 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP19261.1 - 1.6e-05 25.3 0.4 0.0042 17.6 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19261.1 - 5.7e-05 23.2 0.5 0.023 15.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP19261.1 - 8.2e-05 22.8 0.5 0.00073 19.7 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KFP19261.1 - 0.00083 18.4 0.2 0.0011 18.0 0.2 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KFP19261.1 - 0.0021 17.9 3.3 0.31 11.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP19261.1 - 0.0047 17.5 0.4 0.26 12.0 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 KFP19261.1 - 0.056 13.5 0.5 19 5.4 0.0 3.0 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 KFP19261.1 - 0.084 13.2 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFP19261.1 - 0.12 11.6 0.1 0.41 9.8 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFP19261.1 - 0.18 12.3 0.4 3 8.3 0.0 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation KxDL PF10241.9 KFP19262.1 - 3.8e-30 104.0 1.6 6.1e-30 103.3 1.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein BSMAP PF12280.8 KFP19263.1 - 1.4e-18 67.8 0.0 1.5e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF997 PF06196.12 KFP19263.1 - 0.022 14.8 0.9 0.027 14.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) TrkA_TMD PF18613.1 KFP19263.1 - 0.05 13.0 5.0 0.074 12.5 5.0 1.3 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain Kelch_1 PF01344.25 KFP19264.1 - 1.2e-36 124.1 20.2 7.1e-09 35.1 0.4 6.3 5 2 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KFP19264.1 - 3e-34 116.2 3.4 5.1e-06 26.6 0.0 5.5 2 1 3 5 5 5 5 Kelch motif BACK PF07707.15 KFP19264.1 - 6.6e-26 90.4 0.7 1.3e-25 89.5 0.7 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP19264.1 - 2.6e-18 65.2 8.8 0.00015 21.6 0.1 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFP19264.1 - 5.2e-18 64.8 1.8 0.0025 17.8 0.0 5.3 3 1 2 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP19264.1 - 3.7e-15 55.8 0.4 0.0004 20.6 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KFP19264.1 - 3.2e-12 46.6 0.0 7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 KFP19264.1 - 7.1e-10 38.7 7.2 0.085 12.9 0.1 5.4 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.6 KFP19264.1 - 0.016 15.7 0.0 25 5.5 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain TORC_M PF12885.7 KFP19265.1 - 1e-68 230.2 9.0 1e-68 230.2 9.0 2.8 3 1 0 3 3 3 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.7 KFP19265.1 - 5e-33 113.5 2.3 1.4e-32 112.1 2.3 1.8 1 0 0 1 1 1 1 Transducer of regulated CREB activity, C terminus TSP_C PF05735.12 KFP19266.1 - 9.9e-99 329.1 1.1 1.3e-98 328.8 1.1 1.1 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.18 KFP19266.1 - 7.2e-52 172.8 134.7 2.8e-11 42.9 11.0 9.4 7 2 1 8 8 8 7 Thrombospondin type 3 repeat EGF_CA PF07645.15 KFP19266.1 - 2.7e-18 65.9 42.8 4.5e-09 36.4 6.8 5.5 4 0 0 4 4 4 4 Calcium-binding EGF domain COMP PF11598.8 KFP19266.1 - 5.8e-17 61.9 1.8 1.3e-16 60.8 1.8 1.6 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein cEGF PF12662.7 KFP19266.1 - 2.3e-11 43.4 27.0 1e-05 25.4 3.5 5.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP19266.1 - 2.3e-07 30.9 50.4 0.00037 20.6 3.9 6.0 6 0 0 6 6 6 4 EGF domain EGF_MSP1_1 PF12946.7 KFP19266.1 - 0.0058 16.7 4.4 0.0058 16.7 4.4 4.7 4 0 0 4 4 4 2 MSP1 EGF domain 1 UPF1_Zn_bind PF09416.10 KFP19267.1 - 3.6e-75 251.0 6.7 1.4e-74 249.1 6.9 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KFP19267.1 - 4.6e-61 205.9 0.0 8e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP19267.1 - 4.4e-48 164.4 2.2 6.5e-27 95.0 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFP19267.1 - 2.8e-31 107.6 0.0 8e-31 106.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFP19267.1 - 1.3e-13 51.1 0.1 2e-12 47.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFP19267.1 - 1.5e-10 41.6 0.1 6.1e-10 39.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 KFP19267.1 - 1.4e-05 25.2 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFP19267.1 - 0.0001 21.6 0.0 0.0076 15.5 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KFP19267.1 - 0.00045 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Helicase ATPase PF06745.13 KFP19267.1 - 0.00074 18.9 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 KaiC SRP54 PF00448.22 KFP19267.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 KFP19267.1 - 0.017 14.6 0.1 0.85 9.1 0.0 2.7 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KFP19267.1 - 0.045 12.9 0.0 5 6.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 KFP19267.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 KFP19267.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.6 KFP19267.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KFP19267.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TGF_beta PF00019.20 KFP19268.1 - 3.8e-32 111.4 0.0 7.9e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP19268.1 - 2.4e-05 24.2 0.1 3.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TRAM_LAG1_CLN8 PF03798.16 KFP19270.1 - 2.4e-37 128.6 26.4 2.8e-37 128.4 26.4 1.0 1 0 0 1 1 1 1 TLC domain Coatomer_E PF04733.14 KFP19271.1 - 8.7e-114 379.8 4.7 9.7e-114 379.7 4.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFP19271.1 - 1.1e-09 38.7 9.1 3.1e-05 24.4 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19271.1 - 2.9e-09 37.0 6.1 0.015 16.1 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP19271.1 - 2.7e-08 33.9 0.7 0.0071 16.5 0.2 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFP19271.1 - 4.2e-07 29.6 4.6 0.0009 19.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19271.1 - 1.3e-05 25.4 1.8 0.0046 17.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19271.1 - 2.3e-05 24.9 2.6 0.0043 17.7 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19271.1 - 0.00057 19.6 5.0 0.0073 16.1 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19271.1 - 0.00059 19.7 1.3 0.0051 16.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat CysG_dimeriser PF10414.9 KFP19271.1 - 0.039 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region HemY_N PF07219.13 KFP19271.1 - 0.063 13.5 1.1 6.9 6.9 0.7 2.6 2 1 0 2 2 2 0 HemY protein N-terminus PPR PF01535.20 KFP19271.1 - 0.097 13.0 3.0 14 6.2 0.0 3.8 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.6 KFP19271.1 - 0.1 13.3 5.6 1.9 9.3 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP19271.1 - 0.12 12.3 0.3 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 KFP19272.1 - 1.6e-31 109.4 0.0 1.6e-31 109.4 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP19272.1 - 9.4e-28 96.8 0.1 4.3e-27 94.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WH1 PF00568.23 KFP19273.1 - 9.4e-37 125.3 0.2 1.8e-36 124.5 0.2 1.5 1 0 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KFP19273.1 - 0.15 12.4 1.9 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 VID27 PH-like domain GAS PF13851.6 KFP19273.1 - 0.34 10.2 32.8 2.9 7.2 26.8 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3461 PF11944.8 KFP19273.1 - 0.62 10.2 13.5 0.029 14.5 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) Flu_M1_C PF08289.11 KFP19273.1 - 2.2 8.5 5.1 0.56 10.5 0.7 2.3 3 1 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain PKcGMP_CC PF16808.5 KFP19273.1 - 2.3 8.2 13.0 0.099 12.5 2.3 3.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Laminin_II PF06009.12 KFP19273.1 - 4.5 7.3 14.1 1.6 8.7 4.9 3.2 3 0 0 3 3 3 0 Laminin Domain II DUF948 PF06103.11 KFP19273.1 - 6.1 7.2 7.1 11 6.3 0.5 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Surp PF01805.20 KFP19274.1 - 5.5e-15 55.1 1.8 8.4e-10 38.5 0.1 2.6 2 0 0 2 2 2 2 Surp module G-patch PF01585.23 KFP19274.1 - 9.1e-14 51.1 3.9 1.6e-13 50.3 3.9 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP19274.1 - 0.0054 16.8 2.6 0.015 15.3 2.6 1.8 1 0 0 1 1 1 1 G-patch domain PHC2_SAM_assoc PF16616.5 KFP19274.1 - 0.015 16.1 1.3 0.047 14.5 1.3 1.8 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Nop14 PF04147.12 KFP19274.1 - 0.069 11.4 10.9 0.13 10.5 10.9 1.4 1 0 0 1 1 1 0 Nop14-like family DUF2591 PF10765.9 KFP19274.1 - 0.093 13.0 0.8 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) CDC45 PF02724.14 KFP19274.1 - 0.28 9.4 4.3 0.49 8.6 4.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Arm PF00514.23 KFP19275.1 - 1.9e-11 43.6 0.9 0.085 12.9 0.0 5.7 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFP19275.1 - 0.0003 20.8 5.5 0.14 12.2 0.2 4.6 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain UBA_3 PF09288.10 KFP19275.1 - 0.045 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UNC45-central PF11701.8 KFP19275.1 - 0.046 13.7 0.7 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Mito_carr PF00153.27 KFP19276.1 - 3.3e-73 241.7 2.1 1.2e-26 92.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFP19276.1 - 0.0011 18.2 3.9 0.52 9.4 0.1 3.9 2 2 2 4 4 4 2 Gammaproteobacterial serine protease BORCS8 PF10167.9 KFP19277.1 - 1.4e-17 63.6 0.1 1.4e-17 63.6 0.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 F_actin_bund_C PF18060.1 KFP19278.1 - 0.051 13.7 0.1 0.058 13.5 0.1 1.0 1 0 0 1 1 1 0 F actin bundling C terminal ApeA_NTD1 PF18862.1 KFP19279.1 - 0.0008 19.1 0.1 0.0011 18.7 0.1 1.1 1 0 0 1 1 1 1 ApeA N-terminal domain 1 F5_F8_type_C PF00754.25 KFP19279.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 KFP19279.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Methyltransf_PK PF05891.12 KFP19280.1 - 1e-92 309.6 0.0 1.2e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFP19280.1 - 7.8e-13 48.9 0.0 2.4e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP19280.1 - 6e-11 42.9 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP19280.1 - 1.6e-09 38.4 0.0 2.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFP19280.1 - 9.5e-06 25.1 0.0 1.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KFP19280.1 - 4.1e-05 23.4 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP19280.1 - 7.5e-05 22.2 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFP19280.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Dioxygenase_N PF04444.14 KFP19280.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus DREV PF05219.12 KFP19280.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.16 KFP19280.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_4 PF13637.6 KFP19281.1 - 2.4e-22 79.0 0.9 1.4e-05 25.5 0.0 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP19281.1 - 1.3e-18 66.5 1.1 3.7e-07 30.3 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFP19281.1 - 2.9e-16 59.3 1.8 3.2e-07 30.5 0.0 5.3 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP19281.1 - 1.4e-15 55.8 0.4 1.3e-06 28.3 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 KFP19281.1 - 2.5e-15 56.8 0.0 1.4e-06 28.8 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) SOCS_box PF07525.16 KFP19281.1 - 5.9e-12 45.7 7.1 1.1e-11 44.9 2.2 2.7 2 0 0 2 2 2 1 SOCS box N_methyl PF07963.12 KFP19281.1 - 0.15 11.7 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif Homeodomain PF00046.29 KFP19282.1 - 2.9e-23 81.5 6.9 5.7e-23 80.5 6.9 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP19282.1 - 3.7e-08 32.9 0.1 9.1e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP19282.1 - 0.00029 20.7 0.1 0.00029 20.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain MAPEG PF01124.18 KFP19283.1 - 1.1e-22 80.3 0.2 1.3e-22 80.1 0.2 1.0 1 0 0 1 1 1 1 MAPEG family HRCT1 PF15758.5 KFP19283.1 - 0.048 14.6 0.0 0.073 14.0 0.0 1.2 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 Torsin PF06309.11 KFP19284.1 - 2.7e-43 147.1 0.2 4.3e-43 146.4 0.2 1.3 1 0 0 1 1 1 1 Torsin Torsin PF06309.11 KFP19285.1 - 2.2e-47 160.3 0.4 3.6e-47 159.6 0.4 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.29 KFP19285.1 - 0.0071 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP19285.1 - 0.035 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFP19285.1 - 0.038 14.3 0.1 6 7.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain Hep_59 PF07052.11 KFP19286.1 - 1.6e-25 89.9 6.7 1.6e-25 89.9 6.7 2.6 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DHOR PF06537.11 KFP19286.1 - 0.098 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase ArAE_2_N PF10337.9 KFP19286.1 - 0.33 9.9 1.0 0.38 9.7 1.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal UCH PF00443.29 KFP19287.1 - 1.8e-61 207.9 0.0 8.5e-61 205.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFP19287.1 - 4.8e-27 94.4 1.5 1e-15 58.1 0.0 2.9 3 0 0 3 3 3 2 DUSP domain UCH_1 PF13423.6 KFP19287.1 - 1.8e-18 67.2 0.5 5.3e-16 59.1 0.0 4.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP19287.1 - 3.7e-16 59.2 5.2 3.7e-16 59.2 5.2 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein FCH PF00611.23 KFP19288.1 - 2.1e-18 66.3 2.4 2.1e-18 66.3 2.4 3.3 4 1 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFP19288.1 - 6.9e-10 38.6 0.2 1.6e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP19288.1 - 1.5e-09 37.3 0.1 3.5e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP19288.1 - 4.2e-06 26.3 0.1 9.7e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP19288.1 - 0.00014 22.0 0.2 0.00029 21.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.6 KFP19288.1 - 0.00026 21.2 0.6 0.00087 19.5 0.6 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.16 KFP19288.1 - 0.00029 20.9 0.2 0.00029 20.9 0.2 3.0 4 0 0 4 4 4 1 Hr1 repeat Laminin_II PF06009.12 KFP19288.1 - 0.0068 16.4 7.3 0.33 10.9 0.4 3.0 2 1 0 2 2 2 2 Laminin Domain II Spectrin PF00435.21 KFP19288.1 - 0.12 12.9 20.8 0.075 13.5 1.8 4.1 2 1 1 3 3 3 0 Spectrin repeat SH3_16 PF18348.1 KFP19288.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF1664 PF07889.12 KFP19288.1 - 6.1 6.9 14.4 2.8 8.0 1.6 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) EF-hand_7 PF13499.6 KFP19289.1 - 1.9e-17 63.5 0.4 5.4e-16 58.8 0.1 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP19289.1 - 1e-15 56.2 3.3 6.9e-06 25.6 0.1 4.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KFP19289.1 - 8e-15 53.2 4.8 2.9e-06 26.4 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KFP19289.1 - 1.4e-10 40.2 5.5 8.5e-05 21.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFP19289.1 - 4e-06 26.6 2.2 0.023 14.5 0.1 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KFP19289.1 - 0.036 14.0 0.3 5.4 7.0 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand I-set PF07679.16 KFP19290.1 - 3.2e-251 812.4 0.0 2.8e-17 62.6 0.0 20.3 20 0 0 20 20 20 20 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP19290.1 - 6.6e-241 779.7 9.9 6.2e-14 52.4 0.0 20.3 20 0 0 20 20 20 20 Immunoglobulin domain Ig_2 PF13895.6 KFP19290.1 - 1e-167 544.9 0.0 1.1e-09 38.4 0.0 20.2 19 1 1 20 20 20 20 Immunoglobulin domain ig PF00047.25 KFP19290.1 - 1.9e-143 467.0 0.0 3e-09 36.9 0.0 21.7 20 2 0 20 20 20 19 Immunoglobulin domain V-set PF07686.17 KFP19290.1 - 4.2e-71 236.1 25.0 0.00013 22.1 0.0 29.3 21 11 3 25 25 25 14 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP19290.1 - 1.5e-42 142.9 0.0 0.00037 20.0 0.0 15.0 16 0 0 16 16 16 10 Immunoglobulin domain C2-set_2 PF08205.12 KFP19290.1 - 8.4e-41 138.0 30.1 0.00045 20.2 0.1 17.8 17 0 0 17 17 17 12 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP19290.1 - 1.6e-19 70.1 0.0 0.2 12.1 0.0 15.1 17 0 0 17 17 17 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP19290.1 - 4e-16 59.0 0.0 1.8 8.8 0.0 13.5 15 0 0 15 15 15 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP19290.1 - 6e-15 55.1 0.0 5.5 7.1 0.0 13.3 16 0 0 16 16 15 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP19290.1 - 6.2e-12 45.7 0.1 23 5.4 0.0 13.0 15 1 0 15 15 15 0 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KFP19290.1 - 9.5e-10 38.4 0.1 36 4.5 0.0 12.2 15 0 0 15 15 13 0 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFP19290.1 - 2.9e-09 37.1 0.0 6.4 7.0 0.0 10.0 12 0 0 12 12 12 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.11 KFP19290.1 - 3.9e-06 26.9 0.0 4.7 7.2 0.0 8.2 10 1 0 10 10 8 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.16 KFP19290.1 - 1.8e-05 23.7 0.0 9.6 4.8 0.0 6.4 8 0 0 8 8 8 2 Alphaherpesvirus glycoprotein E C2-set PF05790.15 KFP19290.1 - 0.00015 21.8 0.0 53 4.1 0.0 8.6 11 0 0 11 11 10 0 Immunoglobulin C2-set domain VWA_2 PF13519.6 KFP19290.1 - 0.0092 16.6 0.0 0.022 15.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain G2F PF07474.12 KFP19291.1 - 1.6e-42 145.4 0.0 2.3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 G2F domain I-set PF07679.16 KFP19291.1 - 3.4e-19 68.7 0.0 1.7e-15 56.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP19291.1 - 1.1e-16 61.2 0.5 1.1e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KFP19291.1 - 1.7e-10 40.9 0.0 3.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KFP19291.1 - 2.3e-09 37.4 0.0 9e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain EGF_CA PF07645.15 KFP19291.1 - 2e-07 31.1 0.9 2e-07 31.1 0.9 3.0 4 0 0 4 4 4 1 Calcium-binding EGF domain V-set PF07686.17 KFP19291.1 - 0.00053 20.1 0.2 0.6 10.3 0.0 3.2 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP19291.1 - 0.0067 16.0 0.0 0.35 10.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain cEGF PF12662.7 KFP19291.1 - 0.0074 16.2 0.0 0.0074 16.2 0.0 3.2 4 0 0 4 4 4 2 Complement Clr-like EGF-like C2-set_2 PF08205.12 KFP19291.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain hEGF PF12661.7 KFP19291.1 - 0.014 16.0 2.4 0.014 16.0 2.4 3.2 4 0 0 4 4 3 0 Human growth factor-like EGF Ig_5 PF16681.5 KFP19291.1 - 0.043 14.2 0.0 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain FXa_inhibition PF14670.6 KFP19291.1 - 0.083 13.2 8.1 0.16 12.3 4.1 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP19291.1 - 0.27 11.5 1.2 0.85 9.9 1.2 1.9 1 0 0 1 1 1 0 EGF domain EGF PF00008.27 KFP19291.1 - 0.39 11.1 9.8 0.13 12.6 4.9 2.6 2 0 0 2 2 2 0 EGF-like domain Arginosuc_synth PF00764.19 KFP19292.1 - 3.6e-147 490.7 0.0 4.7e-147 490.3 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KFP19292.1 - 4.5e-05 23.1 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFP19292.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase KH_1 PF00013.29 KFP19293.1 - 1.2e-69 230.0 17.2 3.1e-19 68.6 0.3 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFP19293.1 - 4.8e-22 77.6 8.9 1.3e-05 24.9 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFP19293.1 - 1.8e-12 47.0 8.4 0.025 14.4 0.1 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KFP19293.1 - 0.00061 19.2 8.9 0.0014 18.0 8.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) KH_5 PF13184.6 KFP19293.1 - 0.0042 17.2 10.3 10 6.3 0.1 4.4 4 0 0 4 4 4 3 NusA-like KH domain KH_6 PF15985.5 KFP19294.1 - 7.6e-14 51.8 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KFP19294.1 - 7.4e-07 28.9 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pkinase_Tyr PF07714.17 KFP19295.1 - 6e-99 330.5 0.0 8.5e-99 330.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP19295.1 - 5.1e-48 163.7 0.0 8.5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.10 KFP19295.1 - 7.4e-30 103.3 0.2 1.6e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.24 KFP19295.1 - 1e-23 83.2 0.2 2.7e-23 81.9 0.2 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP19295.1 - 1.6e-12 46.8 0.0 2.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP19295.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP19295.1 - 1.7e-07 30.8 0.0 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP19295.1 - 5.8e-05 23.3 0.2 0.00016 21.8 0.2 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Haspin_kinase PF12330.8 KFP19295.1 - 0.0011 18.1 0.1 0.002 17.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain SH3_6 PF12913.7 KFP19295.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) Fibrinogen_C PF00147.18 KFP19296.1 - 6e-52 176.6 3.4 8.7e-52 176.1 3.4 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain CENP-F_leu_zip PF10473.9 KFP19296.1 - 0.11 12.5 1.0 0.17 11.9 1.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 KFP19296.1 - 0.13 12.7 4.3 0.45 11.0 0.5 2.3 2 0 0 2 2 2 0 Snapin/Pallidin CFC PF09443.10 KFP19296.1 - 0.15 11.9 1.8 0.39 10.6 1.8 1.7 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) ATG16 PF08614.11 KFP19296.1 - 0.44 10.8 4.3 0.67 10.2 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Flagellin_N PF00669.20 KFP19296.1 - 0.92 9.6 4.6 1.5 8.9 4.6 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region EF-hand_7 PF13499.6 KFP19297.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP19297.1 - 0.0037 16.7 3.4 0.14 11.8 0.7 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP19297.1 - 0.0049 16.7 0.1 0.079 12.9 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain UPF0154 PF03672.13 KFP19297.1 - 0.019 15.0 1.2 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TOPRIM_C PF16898.5 KFP19297.1 - 0.077 13.3 0.2 0.1 12.9 0.2 1.1 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM PAP2 PF01569.21 KFP19300.1 - 5.4e-14 52.1 4.2 8.4e-14 51.5 4.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFP19300.1 - 0.00072 19.3 7.5 0.0019 17.9 7.5 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFP19300.1 - 0.027 15.0 0.6 0.027 15.0 0.6 1.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PMT PF02366.18 KFP19301.1 - 9.2e-89 297.2 22.5 9.2e-89 297.2 22.5 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFP19301.1 - 5.1e-53 179.6 12.4 5.1e-53 179.6 12.4 2.7 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFP19301.1 - 7e-13 48.8 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 MIR domain HPP PF04982.13 KFP19301.1 - 0.041 14.1 0.4 0.041 14.1 0.4 3.6 4 1 0 4 4 4 0 HPP family CD225 PF04505.12 KFP19302.1 - 3.1e-21 75.3 0.9 3.8e-21 75.0 0.9 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Mak10 PF04112.13 KFP19302.1 - 0.15 11.6 0.1 0.18 11.3 0.1 1.0 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF4190 PF13828.6 KFP19302.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) RasGEF PF00617.19 KFP19303.1 - 5.8e-53 179.7 0.7 2.4e-52 177.7 0.3 2.2 1 1 1 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFP19303.1 - 4.9e-07 29.9 0.4 4.9e-07 29.9 0.4 3.2 4 0 0 4 4 4 1 RasGEF N-terminal motif IML1 PF12257.8 KFP19304.1 - 6.6e-114 379.9 0.2 1.1e-113 379.1 0.2 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KFP19304.1 - 5.5e-10 39.2 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FGGY_N PF00370.21 KFP19304.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF3375 PF11855.8 KFP19304.1 - 0.2 10.6 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) PS_Dcarbxylase PF02666.15 KFP19305.1 - 3.7e-67 225.8 0.0 4.7e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EIF4E-T PF10477.9 KFP19306.1 - 1.7e-156 522.8 19.8 3e-155 518.7 19.8 2.5 1 1 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Glycolytic PF00274.19 KFP19306.1 - 0.2 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I MMR_HSR1_Xtn PF16897.5 KFP19307.1 - 1.2e-45 153.9 0.3 2.1e-45 153.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFP19307.1 - 7.1e-25 86.8 0.1 1.6e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFP19307.1 - 1.8e-19 69.9 0.1 3.9e-19 68.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP19307.1 - 9.6e-11 41.4 0.1 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KFP19307.1 - 0.0032 16.5 0.3 0.023 13.7 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFP19307.1 - 0.0046 17.0 0.3 2.6 8.1 0.2 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFP19307.1 - 0.0055 16.3 0.1 4.1 6.9 0.0 3.7 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain zf-C2H2_4 PF13894.6 KFP19308.1 - 5.6e-31 104.5 48.4 0.00018 22.1 1.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP19308.1 - 1e-28 98.1 51.2 0.0001 22.5 0.8 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_assoc3 PF16637.5 KFP19308.1 - 1.1e-28 99.2 4.6 1.1e-28 99.2 4.6 2.6 4 0 0 4 4 2 1 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-C2H2_jaz PF12171.8 KFP19308.1 - 2.3e-15 56.4 25.5 0.0015 18.8 0.6 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFP19308.1 - 1.1e-14 54.0 58.7 3e-06 27.4 2.2 10.2 11 0 0 11 11 10 4 Zinc-finger double domain zf-met PF12874.7 KFP19308.1 - 1.2e-12 47.8 27.1 0.027 14.8 0.6 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP19308.1 - 1.6e-11 43.9 45.6 1.4e-05 24.9 3.1 8.4 8 0 0 8 8 8 4 C2H2-type zinc finger zf-Di19 PF05605.12 KFP19308.1 - 3.8e-05 23.9 29.7 0.052 13.8 1.1 5.9 3 1 2 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KFP19308.1 - 0.00027 21.6 19.9 0.014 16.1 0.9 5.5 2 2 2 4 4 4 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KFP19308.1 - 0.00077 19.5 26.5 0.068 13.3 0.5 5.7 4 1 2 6 6 6 3 Zinc ribbon domain zf_UBZ PF18439.1 KFP19308.1 - 0.0054 16.3 18.5 7.3 6.3 0.1 8.0 8 0 0 8 8 8 1 Ubiquitin-Binding Zinc Finger ROS_MUCR PF05443.11 KFP19308.1 - 0.012 15.6 0.1 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_8 PF15909.5 KFP19308.1 - 0.036 14.4 16.0 0.033 14.5 4.7 3.9 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFP19308.1 - 0.046 14.1 27.1 35 4.8 2.5 7.3 3 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 KFP19308.1 - 0.047 14.1 0.1 0.047 14.1 0.1 4.3 4 2 1 5 5 5 0 Arsenite-resistance protein 2 DUF629 PF04780.12 KFP19308.1 - 0.054 12.0 8.3 5.2 5.5 2.4 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF629) zf_C2H2_13 PF18508.1 KFP19308.1 - 0.067 12.8 6.3 0.61 9.7 0.1 3.6 3 0 0 3 3 3 0 Zinc finger domain zf-WRNIP1_ubi PF18279.1 KFP19308.1 - 0.086 13.5 1.5 32 5.5 0.0 4.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 KFP19308.1 - 0.57 10.7 0.1 0.57 10.7 0.1 5.4 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFP19308.1 - 0.74 9.7 22.4 5.1 7.0 0.5 6.2 6 1 1 7 7 7 0 GAGA factor DZR PF12773.7 KFP19308.1 - 1.1 9.3 26.3 2.5 8.2 0.2 4.8 4 1 1 5 5 4 0 Double zinc ribbon zf-C2H2_9 PF16293.5 KFP19308.1 - 2.3 8.2 13.8 1.9 8.4 0.0 5.3 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) DNA_ligase_ZBD PF03119.16 KFP19308.1 - 4.3 7.4 6.8 32 4.6 0.1 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DUF4059 PF13268.6 KFP19309.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) Pkinase_Tyr PF07714.17 KFP19310.1 - 4.5e-47 160.5 1.4 1.9e-44 151.9 0.3 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP19310.1 - 4.5e-47 160.6 0.0 7e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 KFP19310.1 - 8.5e-27 93.2 20.4 3.3e-17 62.5 6.7 2.6 2 0 0 2 2 2 2 LIM domain PDZ PF00595.24 KFP19310.1 - 2e-15 56.9 0.0 3.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 KFP19310.1 - 8.3e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_6 PF17820.1 KFP19310.1 - 0.00029 20.6 0.1 0.00061 19.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFP19310.1 - 0.005 16.8 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2175 PF09943.9 KFP19310.1 - 2.1 8.7 7.0 1.4 9.3 1.5 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RRN7 PF11781.8 KFP19310.1 - 5.4 6.8 12.9 0.61 9.8 0.9 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C3HC4_3 PF13920.6 KFP19311.1 - 7.5e-11 41.7 5.4 1e-10 41.3 5.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP19311.1 - 1.8e-10 40.5 7.5 2.5e-10 40.0 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP19311.1 - 6.5e-10 39.2 9.7 8.9e-10 38.8 9.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP19311.1 - 3.4e-09 36.4 8.9 5.1e-09 35.8 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP19311.1 - 2.2e-07 30.6 6.7 3.2e-07 30.1 6.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP19311.1 - 2.9e-07 30.4 6.4 3.6e-06 26.9 7.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP19311.1 - 6.5e-07 29.2 6.4 9.4e-07 28.7 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFP19311.1 - 9.8e-06 25.8 7.0 1.6e-05 25.1 7.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFP19311.1 - 8.3e-05 22.6 2.6 0.00013 22.0 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFP19311.1 - 0.00049 20.2 7.5 0.00074 19.6 7.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFP19311.1 - 0.00062 19.7 2.7 0.00095 19.1 2.7 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KFP19311.1 - 0.01 15.2 0.2 0.013 14.9 0.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UDP PF14569.6 KFP19311.1 - 0.015 15.4 1.5 0.041 14.0 1.5 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KFP19311.1 - 0.026 14.3 5.8 0.057 13.2 5.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFP19311.1 - 0.16 11.6 5.5 0.25 11.0 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 KFP19311.1 - 0.29 11.4 7.5 0.85 9.9 3.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 KFP19311.1 - 1.2 9.3 5.2 3 8.0 5.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KFP19311.1 - 3.2 7.6 9.9 0.32 10.8 5.2 1.8 2 0 0 2 2 2 0 RING-like zinc finger DUF2011 PF09428.10 KFP19312.1 - 0.032 14.5 1.3 0.28 11.4 0.4 2.2 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2011) T3SS_needle_E PF08988.10 KFP19312.1 - 0.04 14.1 0.3 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle HNF-1B_C PF04812.13 KFP19313.1 - 6.3e-98 327.4 37.7 1e-97 326.7 37.7 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.13 KFP19313.1 - 5e-59 200.2 0.1 5e-59 200.2 0.1 2.8 2 1 0 3 3 3 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeodomain PF00046.29 KFP19313.1 - 6.7e-05 22.7 2.1 0.00071 19.4 2.1 2.5 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP19313.1 - 0.03 14.2 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain YwpF PF14183.6 KFP19313.1 - 0.25 11.4 0.7 25 4.9 0.0 2.3 2 0 0 2 2 2 0 YwpF-like protein Peptidase_A22B PF04258.13 KFP19314.1 - 2.2e-94 316.2 9.1 2.9e-94 315.8 9.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Acyl-CoA_dh_1 PF00441.24 KFP19315.1 - 4.3e-51 173.0 7.6 6.7e-51 172.4 7.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP19315.1 - 3.5e-37 127.5 0.3 1.5e-36 125.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP19315.1 - 3e-26 91.4 0.0 5.5e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP19315.1 - 7.4e-25 87.8 4.6 1.1e-24 87.2 4.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF743 PF05332.11 KFP19315.1 - 0.059 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) GMP_PDE_delta PF05351.11 KFP19316.1 - 5.7e-77 257.2 1.5 6.4e-77 257.0 1.5 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Malectin PF11721.8 KFP19317.1 - 5.7e-40 137.1 0.3 5.7e-40 137.1 0.3 1.4 2 0 0 2 2 2 1 Malectin domain Malectin_like PF12819.7 KFP19317.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Malectin-like domain EF-hand_1 PF00036.32 KFP19318.1 - 5.7e-31 103.7 15.3 3.6e-10 38.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFP19318.1 - 4.3e-26 91.2 7.3 3.2e-15 56.3 1.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP19318.1 - 2.1e-25 86.4 6.0 4e-09 35.7 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP19318.1 - 2.3e-20 71.1 11.3 3.1e-08 32.8 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP19318.1 - 4e-20 71.4 13.1 1.8e-12 46.9 0.5 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KFP19318.1 - 4.4e-09 36.5 0.1 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KFP19318.1 - 1.4e-05 25.2 0.1 0.0015 18.7 0.3 2.6 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KFP19318.1 - 2e-05 24.8 0.1 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KFP19318.1 - 0.00016 21.7 0.2 0.4 10.6 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_4 PF12763.7 KFP19318.1 - 0.0027 17.6 1.5 0.052 13.5 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand POTRA_2 PF08479.11 KFP19318.1 - 0.0096 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type DIMCO_N PF16844.5 KFP19318.1 - 0.0098 16.2 0.1 0.052 13.9 0.0 2.0 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF3349 PF11829.8 KFP19318.1 - 0.018 15.8 0.0 4.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 KFP19318.1 - 0.023 14.6 0.0 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 KFP19318.1 - 0.05 14.5 0.1 1.3 10.0 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain DUF5580 PF17743.1 KFP19318.1 - 0.094 11.2 0.0 0.75 8.3 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF2666 PF10869.8 KFP19318.1 - 0.098 12.9 0.1 7.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) RNase_P_Rpp14 PF01900.19 KFP19319.1 - 4.8e-27 94.2 0.2 6.3e-27 93.8 0.2 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Dynein_light PF01221.18 KFP19320.1 - 2.9e-44 149.3 1.9 3.2e-44 149.1 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.29 KFP19320.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ubie_methyltran PF01209.18 KFP19321.1 - 4.1e-90 301.2 0.0 5.1e-90 300.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFP19321.1 - 4.5e-17 62.5 0.0 1.1e-16 61.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP19321.1 - 5.1e-17 62.4 0.0 3.6e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP19321.1 - 1.6e-14 53.9 0.1 9.7e-13 48.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP19321.1 - 9.6e-09 35.9 0.0 6.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP19321.1 - 8e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP19321.1 - 0.0081 16.0 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase UPF0020 PF01170.18 KFP19321.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Dynein_light PF01221.18 KFP19322.1 - 2e-43 146.6 1.9 2.2e-43 146.5 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Glu-tRNAGln PF02686.15 KFP19323.1 - 4e-13 49.5 0.4 2.4e-12 47.0 0.1 1.9 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit COX6A PF02046.15 KFP19324.1 - 2e-16 60.5 0.0 2.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.22 KFP19325.1 - 1.2e-29 101.9 1.7 2.4e-15 56.1 0.6 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP19325.1 - 7.4e-06 26.0 0.3 0.00052 20.1 0.4 2.7 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP19325.1 - 0.0017 18.3 0.2 0.59 10.2 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP19325.1 - 0.0086 16.3 0.1 0.37 11.0 0.1 2.2 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter NID PF07292.13 KFP19325.1 - 0.097 13.3 0.7 3.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) CSD PF00313.22 KFP19325.1 - 0.24 11.3 1.3 3 7.8 0.3 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Phospholip_A2_1 PF00068.19 KFP19326.1 - 7.5e-37 126.2 12.9 8.9e-37 126.0 12.9 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFP19326.1 - 0.031 14.4 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.12 KFP19326.1 - 0.093 13.0 15.1 0.14 12.4 8.2 2.3 1 1 1 2 2 2 0 Phospholipase A2 SIR2 PF02146.17 KFP19327.1 - 3.1e-51 173.8 0.0 4e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family XPA_N PF01286.18 KFP19327.1 - 0.39 10.8 4.5 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf-ACC PF17848.1 KFP19327.1 - 0.44 10.7 2.7 1.1 9.4 0.1 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Paxillin PF03535.13 KFP19328.1 - 2.5e-92 308.4 23.2 4.6e-92 307.5 23.2 1.4 1 0 0 1 1 1 1 Paxillin family LIM PF00412.22 KFP19328.1 - 2.5e-67 223.0 37.2 3.5e-18 65.6 2.1 4.2 4 0 0 4 4 4 4 LIM domain DUF1797 PF08796.10 KFP19328.1 - 0.24 11.5 0.2 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) Ribosomal_L37e PF01907.19 KFP19328.1 - 0.86 9.8 8.6 19 5.5 0.1 4.0 3 0 0 3 3 3 0 Ribosomal protein L37e Ribosomal_60s PF00428.19 KFP19329.1 - 5.2e-20 71.8 7.7 5.2e-20 71.8 7.7 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KFP19329.1 - 1e-19 70.3 0.1 2.3e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFP19329.1 - 4.5e-19 68.5 0.0 8e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ras PF00071.22 KFP19330.1 - 1.8e-55 187.0 0.9 2.4e-55 186.6 0.9 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP19330.1 - 1.8e-31 108.9 2.0 1.8e-31 108.8 0.2 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP19330.1 - 8.4e-16 57.9 0.3 1.2e-15 57.4 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP19330.1 - 1.1e-06 28.3 0.2 2.2e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP19330.1 - 0.00082 19.4 0.2 0.0015 18.6 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KFP19330.1 - 0.03 14.1 0.2 0.32 10.7 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dioxygenase_N PF04444.14 KFP19330.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Glycoprot_B_PH2 PF17417.2 KFP19330.1 - 0.46 10.8 3.8 2.2 8.7 0.9 2.3 2 1 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain ATG16 PF08614.11 KFP19331.1 - 0.0026 18.0 26.2 0.0026 18.0 26.2 4.0 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) GP57 PF17594.2 KFP19331.1 - 0.19 11.5 5.8 0.12 12.1 0.4 3.2 4 0 0 4 4 4 0 Phage Tail fiber assembly helper gene product 57 CENP-F_leu_zip PF10473.9 KFP19331.1 - 0.61 10.1 73.8 20 5.2 11.1 5.3 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CNH PF00780.22 KFP19332.1 - 2.3e-60 204.6 0.0 5.2e-60 203.4 0.0 1.6 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP19332.1 - 2.9e-60 203.9 3.0 2.8e-59 200.6 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19332.1 - 1e-28 100.4 0.0 2.9e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFP19332.1 - 6.2e-10 39.5 0.0 2.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 PH domain C1_1 PF00130.22 KFP19332.1 - 2.6e-05 24.0 9.2 5.4e-05 23.0 9.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Seadorna_VP7 PF07387.11 KFP19332.1 - 0.00034 19.8 0.1 0.0012 18.0 0.1 1.9 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.24 KFP19332.1 - 0.0026 18.4 1.6 0.0082 16.8 1.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KFP19332.1 - 0.0038 17.2 0.0 0.0038 17.2 0.0 4.8 5 2 0 5 5 5 1 Phosphotransferase enzyme family AMPK1_CBM PF16561.5 KFP19333.1 - 2.5e-35 120.5 0.3 4.7e-35 119.7 0.3 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFP19333.1 - 8.5e-28 96.4 1.8 1.5e-27 95.7 1.8 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KFP19333.1 - 0.0078 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CD225 PF04505.12 KFP19334.1 - 1.8e-18 66.4 0.7 2.3e-18 66.1 0.7 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.6 KFP19334.1 - 0.0043 16.8 4.3 0.02 14.7 4.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) Claudin_3 PF06653.11 KFP19334.1 - 0.018 15.0 1.1 0.022 14.7 1.1 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF5493 PF17597.2 KFP19334.1 - 0.085 13.1 1.4 0.12 12.7 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5493) DUF4698 PF15769.5 KFP19335.1 - 2.2e-171 571.3 14.2 2.4e-171 571.1 14.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) HSP20 PF00011.21 KFP19336.1 - 7.7e-17 61.3 0.0 9.8e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.11 KFP19336.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 YabP family PDZ_5 PF17817.1 KFP19336.1 - 0.048 13.9 0.1 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 PDZ domain SRRM_C PF15230.6 KFP19337.1 - 2.6e-27 95.2 32.0 2.6e-27 95.2 32.0 9.1 4 2 2 6 6 6 1 Serine/arginine repetitive matrix protein C-terminus PBP PF01161.20 KFP19338.1 - 1.3e-15 57.8 0.0 1.6e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ig_3 PF13927.6 KFP19339.1 - 9.4e-24 83.8 4.1 1.5e-10 41.5 0.2 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KFP19339.1 - 3.7e-20 71.8 0.0 4.2e-10 39.5 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KFP19339.1 - 1.7e-13 50.6 5.7 8.2e-08 32.3 0.1 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP19339.1 - 1.9e-13 50.5 3.0 0.0001 22.6 0.2 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KFP19339.1 - 9.5e-11 41.8 3.1 2.3e-06 27.8 0.0 4.1 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP19339.1 - 5.1e-07 29.7 3.7 0.012 15.6 0.8 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP19339.1 - 0.032 13.8 0.1 0.75 9.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain V-set_CD47 PF08204.11 KFP19339.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KFP19339.1 - 0.17 12.2 2.5 14 6.0 0.0 3.9 4 1 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Syndecan PF01034.20 KFP19339.1 - 5.2 7.1 4.4 79 3.3 3.2 2.4 2 0 0 2 2 2 0 Syndecan domain TRP PF06011.12 KFP19340.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ion_trans PF00520.31 KFP19341.1 - 7.7e-54 182.5 62.5 1.1e-27 96.9 30.6 2.2 2 0 0 2 2 2 2 Ion transport protein Pilin_N PF07790.11 KFP19341.1 - 0.087 13.8 0.1 0.62 11.0 0.2 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal ECSCR PF15820.5 KFP19341.1 - 0.1 12.4 0.1 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator ARD PF03079.14 KFP19341.1 - 0.25 11.5 1.8 0.49 10.6 1.8 1.4 1 0 0 1 1 1 0 ARD/ARD' family SurA_N_2 PF13623.6 KFP19341.1 - 1.4 8.8 4.9 0.36 10.7 0.7 2.1 2 0 0 2 2 2 0 SurA N-terminal domain Na_Ca_ex PF01699.24 KFP19342.1 - 2.6e-45 154.1 46.4 1.1e-24 87.1 17.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cyt_c_ox_IV PF12270.8 KFP19342.1 - 0.0041 17.3 5.2 0.0049 17.0 0.0 3.2 3 0 0 3 3 3 1 Cytochrome c oxidase subunit IV PRCH PF03967.13 KFP19342.1 - 0.013 15.8 1.1 0.017 15.4 0.2 1.6 1 1 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF4870 PF09685.10 KFP19342.1 - 0.31 11.2 0.1 0.31 11.2 0.1 4.2 4 2 0 4 4 4 0 Domain of unknown function (DUF4870) RRM_1 PF00076.22 KFP19343.1 - 1.1e-83 275.1 7.1 4.8e-19 67.9 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP19343.1 - 1.4e-08 34.8 0.1 0.9 9.7 0.0 5.8 5 0 0 5 5 5 3 RNA recognition motif RRM_3 PF08777.11 KFP19343.1 - 5.7e-07 29.5 9.8 0.34 11.0 0.1 7.5 6 2 1 7 7 7 3 RNA binding motif RRM_Rrp7 PF17799.1 KFP19343.1 - 7.5e-07 29.1 2.0 0.32 10.8 0.1 5.2 5 0 0 5 5 5 2 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 KFP19343.1 - 3.5e-05 23.8 0.0 0.18 11.9 0.0 4.8 4 2 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFP19343.1 - 0.0003 20.7 0.3 25 5.0 0.0 5.2 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFP19343.1 - 0.002 17.9 0.0 26 4.7 0.0 4.1 4 0 0 4 4 4 0 Occluded RNA-recognition motif T-box PF00907.22 KFP19344.1 - 2e-38 132.5 0.1 3e-31 109.1 0.0 2.3 2 0 0 2 2 2 2 T-box T-box PF00907.22 KFP19345.1 - 3.2e-84 281.8 0.2 3.5e-84 281.6 0.2 1.0 1 0 0 1 1 1 1 T-box DUF2054 PF10218.9 KFP19346.1 - 1e-45 155.1 16.4 1.4e-45 154.7 16.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) APS-reductase_C PF12139.8 KFP19346.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit DUF3369 PF11849.8 KFP19346.1 - 0.039 14.2 0.2 0.081 13.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) F-box-like PF12937.7 KFP19348.1 - 1.9e-13 50.1 0.2 4.6e-13 48.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KFP19348.1 - 1.7e-09 38.1 5.2 6 7.9 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box PF00646.33 KFP19348.1 - 1.9e-09 37.2 0.0 3.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 KFP19348.1 - 0.0062 16.6 0.0 0.074 13.1 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region EF-hand_7 PF13499.6 KFP19349.1 - 4.8e-10 39.8 3.0 5.1e-05 23.7 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP19349.1 - 1.4e-07 30.5 0.1 1.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP19349.1 - 3.1e-05 23.6 0.1 0.00023 20.9 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFP19349.1 - 0.00013 21.3 0.0 0.00032 20.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KFP19349.1 - 0.0072 16.1 0.1 0.5 10.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair Transglut_core2 PF13369.6 KFP19350.1 - 1.2e-42 145.2 0.0 2e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KFP19350.1 - 1.2e-28 99.5 0.3 4.5e-27 94.4 0.0 2.9 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like NO_synthase PF02898.15 KFP19351.1 - 1.6e-190 632.8 0.0 2.3e-190 632.2 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.20 KFP19351.1 - 1.1e-81 273.6 0.0 2.1e-81 272.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP19351.1 - 2e-30 105.9 0.8 3.3e-29 102.0 0.3 2.6 2 1 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KFP19351.1 - 2.5e-21 76.4 0.0 1.6e-20 73.7 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PDZ PF00595.24 KFP19351.1 - 9.2e-16 58.0 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP19351.1 - 2.7e-09 36.7 0.1 7.5e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP19351.1 - 0.00073 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 KFP19352.1 - 5.7e-46 156.9 0.0 7.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP19352.1 - 1.1e-40 139.6 0.0 1.6e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.22 KFP19352.1 - 1.8e-05 24.5 11.8 4.2e-05 23.4 11.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KFP19352.1 - 0.00062 19.2 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP19352.1 - 0.023 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP19352.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFP19352.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP19352.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_2 PF03107.16 KFP19352.1 - 0.33 11.3 6.5 0.78 10.1 6.5 1.6 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 KFP19352.1 - 3.6 8.0 13.2 0.15 12.4 6.9 2.0 2 0 0 2 2 2 0 RING-like domain Rep_fac_C PF08542.11 KFP19353.1 - 7.1e-25 87.2 0.1 2.6e-24 85.4 0.1 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KFP19353.1 - 4.4e-15 56.3 0.0 7.8e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFP19353.1 - 1.8e-13 50.6 0.0 4.6e-11 42.8 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KFP19353.1 - 1.3e-05 25.4 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 KFP19353.1 - 6.2e-05 22.8 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KFP19353.1 - 7.3e-05 22.6 0.1 0.00016 21.5 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KFP19353.1 - 8.5e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP19353.1 - 0.00012 22.3 0.2 0.11 12.7 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFP19353.1 - 0.00027 20.8 0.0 0.005 16.7 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP19353.1 - 0.0024 17.9 0.1 0.017 15.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KFP19353.1 - 0.0024 18.2 0.1 0.2 12.0 0.0 2.7 2 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KFP19353.1 - 0.0039 17.2 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFP19353.1 - 0.004 17.0 0.2 0.034 13.9 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase RuvB_N PF05496.12 KFP19353.1 - 0.009 15.8 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KFP19353.1 - 0.0095 15.7 0.0 0.23 11.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 KFP19353.1 - 0.012 15.1 0.2 0.69 9.3 0.0 2.6 2 1 0 3 3 3 0 PhoH-like protein ResIII PF04851.15 KFP19353.1 - 0.027 14.5 0.0 8.1 6.4 0.0 2.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 KFP19353.1 - 0.033 13.4 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 KFP19353.1 - 0.034 13.6 0.0 0.79 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 KFP19353.1 - 0.045 13.5 0.0 0.37 10.5 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFP19353.1 - 0.067 12.6 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFP19353.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KFP19353.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain SNF2_N PF00176.23 KFP19353.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_25 PF13481.6 KFP19353.1 - 0.12 11.9 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thioredoxin_6 PF13848.6 KFP19353.1 - 0.18 11.7 0.0 0.62 9.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain DTC PF18102.1 KFP19354.1 - 2.4e-60 202.5 0.0 3.6e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Deltex C-terminal domain zf-C3HC4 PF00097.25 KFP19354.1 - 7.5e-06 25.7 1.0 1.9e-05 24.4 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP19354.1 - 1.1e-05 25.6 0.9 6.3e-05 23.2 0.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP19354.1 - 2.1e-05 24.4 0.3 5.8e-05 23.0 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP19354.1 - 4e-05 23.8 1.9 0.00015 22.0 0.7 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP19354.1 - 0.00024 21.0 0.8 0.00053 19.9 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KFP19354.1 - 0.0012 18.6 1.3 0.62 9.9 0.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KFP19354.1 - 0.0044 17.0 1.7 0.015 15.3 1.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFP19354.1 - 0.0089 15.9 2.8 0.48 10.3 0.4 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.9 KFP19354.1 - 0.033 14.4 0.8 0.033 14.4 0.8 2.3 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-UDP PF14569.6 KFP19354.1 - 0.038 14.1 0.8 0.073 13.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger PHD PF00628.29 KFP19354.1 - 0.15 11.9 0.4 0.15 11.9 0.4 1.9 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 KFP19354.1 - 0.35 11.1 2.2 1.1 9.5 2.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KFP19354.1 - 0.79 9.9 3.4 0.61 10.3 0.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ADK_lid PF05191.14 KFP19354.1 - 1.8 8.6 8.7 9.4 6.3 0.1 3.9 4 0 0 4 4 4 0 Adenylate kinase, active site lid RRM_1 PF00076.22 KFP19355.1 - 2.9e-10 39.8 0.0 1.2e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS2 PF02187.17 KFP19356.1 - 3e-31 107.3 0.1 5.2e-31 106.6 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFP19356.1 - 2.4e-14 53.4 0.3 3.8e-14 52.8 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Adaptin_N PF01602.20 KFP19357.1 - 1.2e-164 548.8 15.1 1.5e-164 548.5 15.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFP19357.1 - 9.6e-69 230.6 12.7 1.2e-66 223.7 1.3 3.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KFP19357.1 - 3e-37 127.1 0.1 8e-37 125.8 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KFP19357.1 - 1e-22 80.3 3.9 1.4e-08 35.0 0.0 6.1 3 2 4 7 7 7 6 HEAT repeats HEAT PF02985.22 KFP19357.1 - 2.9e-13 48.8 8.6 0.0081 16.3 0.1 7.4 7 0 0 7 7 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 KFP19357.1 - 7.7e-10 39.1 0.3 7.7e-10 39.1 0.3 2.0 2 0 0 2 2 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 KFP19357.1 - 1.9e-09 37.1 4.2 1.1e-05 24.8 0.3 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KFP19357.1 - 7.4e-07 29.0 4.6 0.02 14.9 0.0 5.5 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFP19357.1 - 1.8e-05 24.9 6.9 0.048 13.9 0.0 5.2 2 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFP19357.1 - 9.2e-05 22.1 2.0 0.76 9.3 0.1 4.1 2 2 1 3 3 3 2 CLASP N terminal Arm_2 PF04826.13 KFP19357.1 - 0.0074 15.8 0.2 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 Armadillo-like UNC45-central PF11701.8 KFP19357.1 - 0.012 15.6 0.6 1.4 8.8 0.0 3.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Alpha_adaptin_C PF02296.16 KFP19357.1 - 0.06 13.5 0.2 0.27 11.4 0.1 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.6 KFP19357.1 - 0.068 13.7 7.6 12 6.5 0.0 5.8 7 0 0 7 7 7 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KFP19357.1 - 0.1 12.9 0.1 84 3.6 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Mo25 PF08569.11 KFP19357.1 - 0.41 10.0 6.5 0.19 11.0 0.3 2.6 2 1 0 2 2 2 0 Mo25-like Sec7_N PF12783.7 KFP19357.1 - 0.68 9.8 7.4 0.3 11.0 0.4 3.5 3 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Filament PF00038.21 KFP19358.1 - 1.7e-37 129.7 15.4 1.7e-37 129.7 15.4 2.2 2 0 0 2 2 2 1 Intermediate filament protein FmiP_Thoc5 PF09766.9 KFP19359.1 - 4.9e-129 430.8 8.3 7.2e-129 430.2 8.3 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 BLOC1_2 PF10046.9 KFP19359.1 - 8.6 6.7 9.2 5.4 7.4 1.0 3.1 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NIPSNAP PF07978.13 KFP19360.1 - 1.7e-37 127.7 0.6 1.3e-33 115.3 0.4 2.3 2 0 0 2 2 2 2 NIPSNAP DUF2748 PF10871.8 KFP19360.1 - 0.008 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2748) ERM PF00769.19 KFP19361.1 - 3.5e-32 112.2 50.3 3.5e-32 112.2 50.3 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 KFP19361.1 - 3e-27 95.4 0.9 3e-27 95.4 0.9 3.0 2 1 1 3 3 3 1 FERM central domain FERM_C PF09380.10 KFP19361.1 - 5.7e-25 87.5 0.1 3e-24 85.2 0.0 2.2 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP19361.1 - 1.2e-09 38.0 0.1 4.7e-09 36.1 0.1 2.1 1 0 0 1 1 1 1 FERM N-terminal domain EF-hand_1 PF00036.32 KFP19362.1 - 0.0013 18.1 0.2 0.042 13.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFP19362.1 - 0.0031 17.3 1.9 1.1 9.2 0.1 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP19362.1 - 0.0057 16.1 0.5 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 EF hand DUF3271 PF11675.8 KFP19362.1 - 0.033 13.4 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) EF-hand_6 PF13405.6 KFP19362.1 - 0.047 13.6 0.4 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain U79_P34 PF03064.16 KFP19362.1 - 0.094 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-CCCH PF00642.24 KFP19363.1 - 8.9e-09 35.0 2.4 1.4e-08 34.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFP19363.1 - 5.1e-08 32.5 2.9 9e-08 31.7 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-U1 PF06220.12 KFP19363.1 - 2.2e-07 30.5 4.2 3.9e-07 29.7 4.2 1.4 1 0 0 1 1 1 1 U1 zinc finger zf_CCCH_4 PF18345.1 KFP19363.1 - 1.1e-06 28.5 4.3 1.8e-06 27.8 4.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KFP19363.1 - 0.0016 18.8 2.9 0.0028 18.1 2.9 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger DUF4239 PF14023.6 KFP19363.1 - 0.059 13.1 0.1 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) zf-C2H2_jaz PF12171.8 KFP19363.1 - 1.1 9.6 6.9 6.7 7.1 6.9 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CUE PF02845.16 KFP19364.1 - 6.3e-12 45.0 0.1 1.4e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 CUE domain DNA_pol_phi PF04931.13 KFP19364.1 - 1.9 6.5 9.5 4.8 5.2 9.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi RcpC PF16976.5 KFP19364.1 - 5.8 7.0 7.0 3.8 7.6 0.2 2.9 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB Myotub-related PF06602.14 KFP19365.1 - 7.6e-139 462.5 0.1 1.1e-138 462.1 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP19365.1 - 0.00067 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP19365.1 - 0.0028 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP19365.1 - 0.0038 17.2 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFP19365.1 - 0.13 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.24 KFP19366.1 - 9.5e-29 100.5 0.4 9.5e-29 100.5 0.4 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 KFP19366.1 - 3.1e-26 92.2 0.0 8.8e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP19366.1 - 4.5e-14 52.4 0.0 8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP19366.1 - 1.6e-08 34.9 0.3 1e-07 32.3 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HORMA PF02301.18 KFP19367.1 - 7.4e-49 166.2 0.0 4.9e-48 163.5 0.0 1.9 1 1 0 1 1 1 1 HORMA domain LIF_OSM PF01291.17 KFP19368.1 - 8.3e-33 113.8 2.3 9.2e-33 113.7 2.3 1.0 1 0 0 1 1 1 1 LIF / OSM family ACT_7 PF13840.6 KFP19369.1 - 1.1e-31 108.4 0.1 3.2e-18 65.3 0.1 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KFP19369.1 - 4.7e-18 64.8 3.1 1.6e-16 59.8 0.5 2.8 3 0 0 3 3 3 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain RabGAP-TBC PF00566.18 KFP19370.1 - 5.3e-54 183.1 0.0 8.1e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRRCT PF01463.24 KFP19370.1 - 0.25 12.0 2.1 32 5.4 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain GAS PF13851.6 KFP19371.1 - 0.035 13.4 80.8 0.025 13.9 23.8 4.6 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KFP19371.1 - 0.22 11.6 79.6 0.024 14.6 15.7 4.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 KFP19371.1 - 1.3 7.1 63.2 0.13 10.4 58.6 1.5 2 0 0 2 2 2 0 HOOK protein DUF2400 PF09674.10 KFP19371.1 - 7.1 6.5 12.3 0.44 10.5 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) DUF5357 PF17310.2 KFP19371.1 - 8.9 4.8 8.4 0.3 9.6 1.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5357) zf-RING_2 PF13639.6 KFP19372.1 - 1.9e-12 47.3 7.9 3.8e-12 46.3 7.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP19372.1 - 1.4e-10 40.8 3.3 3.2e-10 39.6 3.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP19372.1 - 5.4e-09 35.7 7.9 1e-08 34.9 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP19372.1 - 1.7e-07 31.0 4.8 3.4e-07 30.0 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP19372.1 - 7.1e-07 29.4 9.7 5.1e-06 26.7 9.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP19372.1 - 1.9e-06 27.7 3.9 3.4e-06 26.9 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP19372.1 - 6e-06 26.2 2.0 6e-06 26.2 2.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP19372.1 - 8.5e-05 22.3 2.8 0.00015 21.6 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP19372.1 - 9.5e-05 22.2 5.3 0.00016 21.4 4.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KFP19372.1 - 0.0088 16.1 2.2 0.023 14.7 2.2 1.7 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 KFP19372.1 - 0.037 14.1 4.7 0.14 12.2 4.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZNRF_3_ecto PF18212.1 KFP19372.1 - 0.047 13.7 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 ZNRF-3 Ectodomain PHD PF00628.29 KFP19372.1 - 0.68 9.9 5.4 2 8.4 5.4 1.9 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KFP19372.1 - 1.2 8.8 7.9 2.2 8.0 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFP19372.1 - 4 7.3 6.6 4.8 7.1 5.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFP19372.1 - 5.7 7.1 9.0 5.2 7.3 7.2 1.9 2 0 0 2 2 1 0 RING-variant domain CRAL_TRIO PF00650.20 KFP19373.1 - 3.8e-33 114.5 0.1 5e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP19373.1 - 3.1e-06 27.4 0.0 5.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GOLD_2 PF13897.6 KFP19373.1 - 0.00053 20.5 1.3 0.31 11.5 0.0 3.0 1 1 2 3 3 3 2 Golgi-dynamics membrane-trafficking Pescadillo_N PF06732.11 KFP19374.1 - 1.4e-113 379.0 1.3 1.4e-113 379.0 1.3 2.1 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT_2 PF16589.5 KFP19374.1 - 9.1e-08 32.4 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DNA_pol_phi PF04931.13 KFP19374.1 - 0.036 12.2 19.4 0.052 11.6 19.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KFP19374.1 - 0.54 8.5 21.2 1.1 7.5 21.2 1.5 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 KFP19374.1 - 0.78 8.9 9.7 1.8 7.7 7.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit PRAS PF15798.5 KFP19374.1 - 4.7 7.8 10.1 3.5 8.2 7.9 1.9 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 CENP-B_dimeris PF09026.10 KFP19374.1 - 8.5 6.8 17.2 23 5.5 17.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IQ PF00612.27 KFP19375.1 - 2.3e-06 26.9 0.4 2.3e-06 26.9 0.4 2.5 3 0 0 3 3 3 1 IQ calmodulin-binding motif GAS PF13851.6 KFP19375.1 - 0.013 14.9 4.3 0.013 14.9 4.3 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SIKE PF05769.11 KFP19375.1 - 0.12 12.3 8.2 0.92 9.4 4.3 2.3 2 0 0 2 2 2 0 SIKE family PH_8 PF15409.6 KFP19376.1 - 2.8e-05 24.3 0.1 0.00011 22.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFP19376.1 - 3.1e-05 24.4 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 PH domain Oxysterol_BP PF01237.18 KFP19376.1 - 6.4e-05 22.0 0.2 0.00013 21.0 0.2 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Syntaxin-6_N PF09177.11 KFP19376.1 - 0.0059 17.1 7.7 0.07 13.7 0.4 3.4 1 1 1 3 3 3 1 Syntaxin 6, N-terminal PH_11 PF15413.6 KFP19376.1 - 0.0083 16.5 0.1 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KFP19376.1 - 0.012 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 KFP19376.1 - 0.021 14.7 0.3 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Spc7 PF08317.11 KFP19376.1 - 0.028 13.3 2.6 0.044 12.7 2.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein betaPIX_CC PF16523.5 KFP19376.1 - 0.065 13.1 0.6 0.14 12.0 0.6 1.5 1 0 0 1 1 1 0 betaPIX coiled coil Flu_B_NS1 PF02942.14 KFP19376.1 - 0.11 11.5 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) HlyD_D23 PF16576.5 KFP19376.1 - 0.12 11.6 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MerR-DNA-bind PF09278.11 KFP19376.1 - 1.1 9.9 6.8 1.1 9.9 4.1 2.3 2 0 0 2 2 2 0 MerR, DNA binding Oxysterol_BP PF01237.18 KFP19377.1 - 7.4e-31 107.3 0.3 8.2e-31 107.2 0.3 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Pro_dh PF01619.18 KFP19379.1 - 1.3e-65 221.9 0.3 1e-63 215.6 0.3 2.0 1 1 0 1 1 1 1 Proline dehydrogenase HrpB2 PF09487.10 KFP19379.1 - 0.025 15.0 0.1 0.07 13.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Laminin_EGF PF00053.24 KFP19380.1 - 7.7e-17 61.2 108.0 0.0028 17.8 13.6 7.8 2 1 5 7 7 7 6 Laminin EGF domain DSL PF01414.19 KFP19380.1 - 0.0036 17.5 14.1 0.0036 17.5 14.1 7.5 5 1 2 7 7 7 3 Delta serrate ligand EGF_2 PF07974.13 KFP19380.1 - 0.0039 17.5 11.4 0.0039 17.5 11.4 11.8 11 2 0 11 11 11 5 EGF-like domain Tweety PF04906.13 KFP19380.1 - 0.05 12.3 2.7 0.074 11.7 2.7 1.1 1 0 0 1 1 1 0 Tweety DGCR6 PF07324.11 KFP19381.1 - 6.7e-52 175.9 6.1 7.4e-52 175.8 6.1 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein P2X_receptor PF00864.19 KFP19382.1 - 2.3e-94 316.5 0.1 2.8e-94 316.2 0.1 1.0 1 0 0 1 1 1 1 ATP P2X receptor Pyr_redox_2 PF07992.14 KFP19383.1 - 3.5e-62 210.3 0.4 4.7e-62 209.9 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP19383.1 - 4.1e-20 72.1 1.6 2.2e-15 57.0 0.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFP19383.1 - 4.8e-19 68.7 3.6 7.7e-15 54.9 0.5 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFP19383.1 - 1.8e-18 66.3 0.2 4e-18 65.2 0.2 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 KFP19383.1 - 3.2e-08 33.7 0.3 0.00013 22.2 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFP19383.1 - 3.9e-08 32.4 3.4 0.0032 16.2 0.1 4.0 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.24 KFP19383.1 - 1.4e-07 31.4 2.0 0.089 12.4 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase Rieske_2 PF13806.6 KFP19383.1 - 3.2e-07 30.2 0.0 8.2e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain FAD_binding_3 PF01494.19 KFP19383.1 - 3.7e-06 26.4 0.8 0.0013 18.1 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 KFP19383.1 - 7.8e-06 25.2 5.5 0.00073 18.7 0.1 3.8 2 1 2 4 4 4 1 FAD binding domain GIDA PF01134.22 KFP19383.1 - 0.00011 21.5 2.5 0.98 8.4 0.0 3.6 3 1 1 4 4 4 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFP19383.1 - 0.00028 20.9 0.6 1.1 9.2 0.1 3.3 3 1 1 4 4 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KFP19383.1 - 0.00037 19.8 1.1 0.1 11.8 0.0 2.7 3 0 0 3 3 3 2 Thi4 family Shikimate_DH PF01488.20 KFP19383.1 - 0.00071 19.6 0.2 0.2 11.7 0.0 2.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFP19383.1 - 0.00093 19.4 0.1 0.96 9.7 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain DUF1188 PF06690.11 KFP19383.1 - 0.003 17.2 0.0 0.88 9.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Reductase_C PF14759.6 KFP19383.1 - 0.0045 17.5 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal ThiF PF00899.21 KFP19383.1 - 0.0057 16.0 1.5 0.32 10.3 0.0 2.6 3 0 0 3 3 2 1 ThiF family ApbA PF02558.16 KFP19383.1 - 0.014 15.1 0.0 0.73 9.5 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KFP19383.1 - 0.019 15.4 1.3 0.83 10.1 0.0 2.9 2 1 0 3 3 3 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFP19383.1 - 0.022 14.4 0.7 1.3 8.6 0.1 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 KFP19383.1 - 0.027 13.6 0.1 0.42 9.7 0.0 2.2 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KFP19383.1 - 0.032 14.1 0.0 0.68 9.8 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 KFP19383.1 - 0.037 14.7 0.0 0.88 10.3 0.0 2.6 2 0 0 2 2 2 0 PglD N-terminal domain Lycopene_cycl PF05834.12 KFP19383.1 - 0.044 12.8 7.4 1.5 7.8 0.5 3.3 2 2 2 4 4 4 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KFP19383.1 - 0.061 12.2 1.3 3.5 6.4 0.1 2.7 2 1 1 3 3 3 0 Tryptophan halogenase DUF4147 PF13660.6 KFP19383.1 - 0.075 12.6 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) AlaDh_PNT_C PF01262.21 KFP19383.1 - 0.74 9.1 4.1 0.9 8.8 0.0 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1744 PF08490.12 KFP19384.1 - 2.2e-142 474.4 0.0 3.5e-142 473.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KFP19384.1 - 1.6e-97 326.7 0.0 9.1e-97 324.2 0.3 2.1 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KFP19384.1 - 2.1e-14 53.1 0.3 1.1e-12 47.5 0.3 3.3 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KFP19384.1 - 9.8e-09 35.2 0.4 4.8e-08 32.9 0.4 2.2 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFP19384.1 - 1.5e-06 28.3 0.2 1.2e-05 25.4 0.1 2.7 2 1 0 2 2 2 1 RNase_H superfamily APP_N PF02177.16 KFP19384.1 - 0.035 14.5 0.3 0.14 12.5 0.3 2.1 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding SKICH PF17751.1 KFP19385.1 - 1e-27 96.7 0.0 2.3e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 KFP19385.1 - 9.1e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HECW_N PF16562.5 KFP19385.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Morc6_S5 PF17942.1 KFP19386.1 - 1e-23 83.9 0.8 1.8e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 KFP19386.1 - 7.9e-15 54.6 4.0 1.9e-14 53.4 4.0 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c_3 PF13589.6 KFP19386.1 - 3.5e-09 36.6 0.0 9e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase XhlA PF10779.9 KFP19386.1 - 3.1 8.1 16.6 3.8 7.8 0.6 3.8 3 0 0 3 3 3 0 Haemolysin XhlA Prominin PF05478.11 KFP19386.1 - 7.3 4.4 8.1 1.8 6.4 0.6 2.2 2 0 0 2 2 2 0 Prominin VWD PF00094.25 KFP19387.1 - 6e-33 114.3 0.5 7e-33 114.1 0.5 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain RRM_1 PF00076.22 KFP19388.1 - 4.7e-26 90.4 0.1 7.4e-26 89.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP19388.1 - 0.00015 21.8 0.1 0.00029 20.9 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KFP19388.1 - 0.00043 20.1 0.0 0.00089 19.1 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP19388.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KFP19388.1 - 0.084 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 KFP19388.1 - 0.38 9.5 2.2 0.5 9.1 2.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DNA_ligase_A_M PF01068.21 KFP19390.1 - 3.5e-54 183.6 0.1 7.5e-54 182.5 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFP19390.1 - 2.4e-41 141.9 0.2 5.1e-41 140.9 0.2 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFP19390.1 - 2.2e-18 66.7 0.0 1.3e-17 64.2 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_IV PF11411.8 KFP19390.1 - 1.1e-17 63.9 0.9 2.5e-17 62.7 0.9 1.7 1 0 0 1 1 1 1 DNA ligase IV BRCT PF00533.26 KFP19390.1 - 8.9e-17 61.3 0.1 1.5e-10 41.3 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFP19390.1 - 1.4e-12 47.8 0.0 7.2e-10 39.2 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KFP19390.1 - 4.4e-11 43.4 0.1 1.3e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 RNA ligase mRNA_cap_enzyme PF01331.19 KFP19390.1 - 0.03 14.2 0.8 0.42 10.4 0.8 2.4 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain APG17 PF04108.12 KFP19390.1 - 0.043 12.9 0.4 0.12 11.5 0.4 1.7 1 0 0 1 1 1 0 Autophagy protein Apg17 SKA1 PF07160.12 KFP19390.1 - 0.18 11.6 2.7 0.28 11.0 1.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 BRCT_3 PF18428.1 KFP19390.1 - 0.53 10.4 2.5 22 5.2 0.0 3.7 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Abhydrolase_1 PF00561.20 KFP19391.1 - 5.2e-16 59.1 0.0 2.4e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP19391.1 - 7.2e-16 58.2 0.0 2.8e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 KFP19391.1 - 2.7e-08 32.9 0.0 0.00028 19.7 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KFP19391.1 - 4.6e-06 27.4 0.0 4e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFP19391.1 - 0.00011 22.1 0.0 0.0071 16.2 0.0 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP19391.1 - 0.0005 20.0 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFP19391.1 - 0.001 18.7 0.0 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KFP19391.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFP19391.1 - 0.0013 18.7 0.0 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KFP19391.1 - 0.0027 17.4 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KFP19391.1 - 0.012 15.2 0.0 0.064 12.8 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 KFP19391.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 KFP19391.1 - 0.054 12.5 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KFP19391.1 - 0.18 11.5 0.1 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein DUF5339 PF17274.2 KFP19391.1 - 0.2 12.5 0.0 0.33 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5339) TNF PF00229.18 KFP19392.1 - 4e-10 39.7 0.0 6.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TED_complement PF07678.14 KFP19396.1 - 4e-46 157.5 0.0 4.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain SQHop_cyclase_C PF13243.6 KFP19396.1 - 0.017 14.3 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Chordopox_A33R PF05966.12 KFP19397.1 - 0.00061 19.1 0.1 0.00089 18.6 0.1 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Lectin_C PF00059.21 KFP19397.1 - 0.0031 18.2 0.0 0.0075 17.0 0.0 1.7 1 0 0 1 1 1 1 Lectin C-type domain UL45 PF05473.12 KFP19397.1 - 0.041 13.5 2.1 0.11 12.1 0.4 2.2 2 1 1 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like RabGAP-TBC PF00566.18 KFP19398.1 - 9.1e-15 54.9 0.5 9.1e-15 54.9 0.5 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cornifin PF02389.15 KFP19399.1 - 3.3e-10 40.3 57.4 2.8e-05 24.3 18.3 3.2 1 1 2 3 3 3 3 Cornifin (SPRR) family UCH PF00443.29 KFP19400.1 - 5.5e-47 160.4 0.0 7.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFP19400.1 - 2e-24 85.1 0.5 2.2e-12 46.6 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KFP19400.1 - 4e-15 55.9 0.0 1.1e-14 54.5 0.0 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFP19400.1 - 2e-10 40.8 0.0 0.00033 20.3 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFP19400.1 - 0.0093 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBA_3 PF09288.10 KFP19400.1 - 0.085 12.7 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain TPR_1 PF00515.28 KFP19401.1 - 1.6e-26 91.0 1.0 1.8e-05 24.3 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19401.1 - 2.3e-22 77.2 5.1 0.00019 21.3 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19401.1 - 8.3e-20 69.3 0.3 0.0022 18.1 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFP19401.1 - 4.1e-15 55.2 1.0 0.0014 18.2 0.0 5.5 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 KFP19401.1 - 8.7e-15 54.2 6.5 0.0034 18.1 0.6 6.5 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFP19401.1 - 2.5e-14 53.5 5.5 0.00084 19.8 2.3 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19401.1 - 8e-14 50.9 9.2 0.0049 17.2 0.5 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19401.1 - 2.7e-11 43.9 6.9 6.2e-06 26.8 0.4 4.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFP19401.1 - 5.3e-11 42.5 4.3 0.00024 21.2 0.4 4.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFP19401.1 - 5.8e-09 36.2 3.8 0.00019 21.7 0.6 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19401.1 - 2e-08 34.4 6.4 0.72 10.2 0.0 4.8 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19401.1 - 4.1e-08 32.7 4.8 2 8.6 0.1 6.4 6 1 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP19401.1 - 4.9e-08 33.1 2.0 0.0013 18.9 1.7 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP19401.1 - 3.4e-07 30.5 4.8 5.9 7.8 0.2 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFP19401.1 - 0.0044 17.0 0.0 4.7 7.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFP19401.1 - 0.0046 16.4 5.2 7.1 6.2 0.1 3.6 3 0 0 3 3 3 1 SHNi-TPR TPR_15 PF13429.6 KFP19401.1 - 0.0062 15.8 4.2 0.053 12.7 0.7 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4248 PF14053.6 KFP19401.1 - 0.011 15.7 0.2 0.032 14.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DUF4919 PF16266.5 KFP19401.1 - 0.031 14.2 0.2 0.082 12.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) BTAD PF03704.17 KFP19401.1 - 0.036 14.5 5.2 7.3 7.0 0.1 3.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 KFP19401.1 - 0.084 12.8 0.6 0.22 11.4 0.6 1.7 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF4192 PF13830.6 KFP19401.1 - 1.3 9.1 4.8 0.84 9.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) TPR_10 PF13374.6 KFP19401.1 - 9.9 6.2 16.7 2.9 7.9 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19402.1 - 4.6e-12 45.2 0.1 0.0047 16.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19402.1 - 8.2e-11 41.2 3.8 0.0061 16.6 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP19402.1 - 4e-10 39.2 0.4 1.5e-08 34.2 0.0 3.0 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 KFP19402.1 - 1.7e-07 30.9 0.8 0.32 11.3 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19402.1 - 5.9e-07 29.8 0.2 0.041 14.7 0.0 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19402.1 - 2.9e-06 27.8 0.1 3.2e-05 24.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP19402.1 - 6.7e-06 26.2 0.0 2.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19402.1 - 8.7e-06 25.8 1.1 0.00032 20.9 0.1 3.6 5 0 0 5 5 3 1 Tetratricopeptide repeat HCNGP PF07818.13 KFP19402.1 - 0.00076 20.1 1.8 0.0035 17.9 0.0 2.6 2 0 0 2 2 2 1 HCNGP-like protein TPR_19 PF14559.6 KFP19402.1 - 0.0017 18.8 4.1 0.019 15.5 0.1 3.4 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19402.1 - 0.0029 17.9 2.0 1.8 8.9 0.9 3.5 1 1 3 4 4 4 1 Tetratricopeptide repeat S1 PF00575.23 KFP19402.1 - 0.0046 17.3 0.0 0.15 12.4 0.0 2.4 1 1 0 1 1 1 1 S1 RNA binding domain Aida_N PF08910.10 KFP19402.1 - 0.62 10.5 5.4 44 4.6 4.2 2.5 2 0 0 2 2 2 0 Aida N-terminus Herpes_pp85 PF04637.12 KFP19402.1 - 1.4 7.2 8.6 2.3 6.6 8.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mem_trans PF03547.18 KFP19402.1 - 5.7 5.2 7.5 9.3 4.5 7.5 1.3 1 0 0 1 1 1 0 Membrane transport protein Miga PF10265.9 KFP19402.1 - 8.1 5.3 18.8 0.065 12.2 10.4 1.8 2 0 0 2 2 2 0 Mitoguardin ABC_tran_CTD PF16326.5 KFP19403.1 - 0.024 14.9 0.7 0.024 14.9 0.7 12.1 4 4 9 13 13 13 0 ABC transporter C-terminal domain Spc7 PF08317.11 KFP19403.1 - 0.95 8.3 157.5 0.054 12.4 13.0 7.2 2 2 4 6 6 6 0 Spc7 kinetochore protein FXMRP1_C_core PF12235.8 KFP19404.1 - 1e-46 159.0 13.7 1e-46 159.0 13.7 3.5 1 1 2 3 3 3 1 Fragile X-related 1 protein core C terminal FXR_C1 PF16096.5 KFP19404.1 - 1.1e-38 131.2 12.0 1.1e-38 131.2 12.0 3.4 2 1 1 3 3 3 1 Fragile X-related 1 protein C-terminal region 2 KH_9 PF17904.1 KFP19404.1 - 9.3e-36 122.1 0.7 2.4e-35 120.8 0.7 1.8 1 0 0 1 1 1 1 FMRP KH0 domain FXR_C3 PF16097.5 KFP19404.1 - 8.1e-27 93.7 7.5 8.1e-27 93.7 7.5 3.1 3 1 1 4 4 4 1 Fragile X-related 1 protein C-terminal region 3 KH_1 PF00013.29 KFP19404.1 - 2.5e-17 62.4 1.0 1.5e-09 37.5 0.5 2.7 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 KFP19404.1 - 2e-08 34.6 0.2 2e-08 34.6 0.2 2.7 3 0 0 3 3 3 1 Agenet domain Tudor_FRX1 PF18336.1 KFP19404.1 - 6.1e-06 26.1 3.0 6.1e-06 26.1 3.0 2.0 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain KH_2 PF07650.17 KFP19404.1 - 0.00024 20.9 0.8 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KFP19404.1 - 0.47 10.4 5.2 2.1 8.3 0.4 3.4 3 1 1 4 4 4 0 KH domain DnaJ PF00226.31 KFP19405.1 - 1.5e-08 34.6 0.0 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KFP19405.1 - 0.00054 20.0 0.0 0.00064 19.7 0.0 1.1 1 0 0 1 1 1 1 Pam16 SOXp PF12336.8 KFP19406.1 - 2.4e-38 131.0 5.4 2.4e-38 131.0 5.4 2.4 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.19 KFP19406.1 - 5.1e-28 97.3 3.4 8.6e-28 96.6 3.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP19406.1 - 5.8e-12 46.0 1.9 1e-11 45.2 1.9 1.4 1 0 0 1 1 1 1 HMG-box domain CaKB PF03185.15 KFP19407.1 - 5.3e-84 280.8 8.5 6.1e-84 280.6 8.5 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit KcnmB2_inactiv PF09303.10 KFP19407.1 - 3e-06 26.9 2.0 3e-06 26.9 2.0 1.6 2 0 0 2 2 2 1 KCNMB2, ball and chain domain AAA_8 PF12780.7 KFP19407.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 tRNA-synt_1g PF09334.11 KFP19407.1 - 0.037 12.8 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-met PF12874.7 KFP19408.1 - 1.9e-22 78.9 16.9 1.4e-08 34.8 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP19408.1 - 8.9e-20 70.5 16.7 9.2e-07 29.0 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP19408.1 - 5.6e-09 36.3 11.9 0.016 15.5 0.5 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFP19408.1 - 0.00035 21.2 5.8 2.5 9.2 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-U1 PF06220.12 KFP19408.1 - 0.00087 19.0 18.3 0.1 12.4 3.0 3.6 3 1 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.12 KFP19408.1 - 0.01 16.1 0.7 0.01 16.1 0.7 3.0 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) PI3Ka PF00613.20 KFP19409.1 - 9.4e-70 233.8 1.9 1.9e-69 232.8 1.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP19409.1 - 6.1e-55 186.7 1.0 4.1e-54 184.0 1.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 KFP19409.1 - 4.3e-39 133.0 1.4 3e-37 127.1 0.7 2.9 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFP19409.1 - 5.7e-33 113.8 0.0 1.1e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_p85B PF02192.16 KFP19409.1 - 8.4e-31 105.5 0.4 2.2e-30 104.2 0.4 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain DUF2321 PF10083.9 KFP19409.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF4135 PF13575.6 KFP19409.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) zf-C2H2 PF00096.26 KFP19410.1 - 2.8e-16 59.0 59.3 0.0025 18.2 1.0 9.7 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19410.1 - 7.6e-14 51.2 60.4 0.0051 17.5 1.3 9.8 9 0 0 9 9 9 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP19410.1 - 1.7e-11 44.0 49.7 0.00017 21.8 0.2 9.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP19410.1 - 2.2e-11 43.3 42.8 5.6e-05 22.8 2.3 7.7 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFP19410.1 - 0.0017 18.3 1.3 0.0017 18.3 1.3 8.3 8 1 0 8 8 8 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFP19410.1 - 0.0022 17.6 44.7 0.021 14.5 0.2 6.8 5 3 1 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KFP19410.1 - 0.061 13.7 1.0 0.061 13.7 1.0 7.4 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 KFP19410.1 - 0.23 12.2 34.4 0.19 12.5 3.5 5.2 3 1 2 5 5 5 0 zinc-ribbon family zf-C2H2_8 PF15909.5 KFP19410.1 - 0.63 10.4 34.8 0.14 12.4 2.3 5.7 2 1 2 5 5 5 0 C2H2-type zinc ribbon CarbpepA_inh PF02977.15 KFP19410.1 - 1.4 8.8 15.2 1.9 8.4 0.0 5.3 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor zf-C2H2_2 PF12756.7 KFP19410.1 - 7.3 7.0 48.9 5.1 7.5 5.2 5.7 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.13 KFP19411.1 - 6.2e-73 243.6 4.7 6.2e-73 243.6 4.7 3.3 2 1 3 5 5 5 1 fzo-like conserved region Dynamin_N PF00350.23 KFP19411.1 - 1.8e-23 83.5 0.0 1.8e-23 83.5 0.0 3.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KFP19411.1 - 4.1e-08 33.3 0.1 3.5e-07 30.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Apolipoprotein PF01442.18 KFP19411.1 - 0.016 15.1 9.7 0.14 12.0 0.4 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Roc PF08477.13 KFP19411.1 - 0.071 13.3 0.2 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase CorA PF01544.18 KFP19411.1 - 0.27 10.5 9.6 0.42 9.9 1.1 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein MobC PF05713.11 KFP19411.1 - 0.43 11.1 2.1 18 5.9 0.1 3.2 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Tup_N PF08581.10 KFP19411.1 - 0.53 10.6 10.4 4.5 7.6 0.3 3.8 3 0 0 3 3 3 0 Tup N-terminal CLZ PF16526.5 KFP19411.1 - 0.57 10.6 9.5 2.2 8.7 0.2 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_TATA_bd PF12325.8 KFP19411.1 - 3.4 7.9 14.7 0.26 11.5 4.7 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.19 KFP19411.1 - 4.8 6.8 13.7 7.9 6.1 3.3 2.8 2 0 0 2 2 2 0 GrpE AAA_23 PF13476.6 KFP19411.1 - 7.1 7.1 0.0 7.1 7.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain Exonuc_VII_L PF02601.15 KFP19411.1 - 9.7 5.7 13.3 1.8 8.1 0.4 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit WD40 PF00400.32 KFP19412.1 - 2e-44 148.7 21.2 4.1e-08 33.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19412.1 - 2.4e-16 59.8 0.0 0.00086 19.6 0.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP19412.1 - 8.4e-05 22.5 0.0 0.42 10.5 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFP19412.1 - 0.00011 21.7 0.0 0.024 14.0 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain Actin PF00022.19 KFP19413.1 - 9.8e-116 386.7 0.0 2e-98 329.7 0.0 2.0 2 0 0 2 2 2 2 Actin MobA_MobL PF03389.15 KFP19413.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 MobA/MobL family MRP-L47 PF06984.13 KFP19414.1 - 4.6e-36 122.8 1.7 7.9e-36 122.1 1.7 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NDUF_B5 PF09781.9 KFP19415.1 - 1.5e-80 269.2 0.8 1.7e-80 269.0 0.8 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit BNIP3 PF06553.12 KFP19416.1 - 2.9e-20 72.8 0.0 3.2e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 BNIP3 CUE PF02845.16 KFP19417.1 - 6.8e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain RD3 PF14473.6 KFP19419.1 - 6.7e-52 174.8 2.8 8.9e-52 174.4 2.8 1.1 1 0 0 1 1 1 1 RD3 protein THAP PF05485.12 KFP19419.1 - 0.04 14.8 0.9 0.16 13.0 0.0 2.2 2 1 0 2 2 2 0 THAP domain Mit_proteolip PF08039.11 KFP19420.1 - 3.8e-08 33.7 1.6 3.8e-08 33.7 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial proteolipid Ank_4 PF13637.6 KFP19421.1 - 7.7e-17 61.4 1.4 7.6e-12 45.5 0.6 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP19421.1 - 8.9e-17 61.5 0.0 1.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KFP19421.1 - 1.6e-13 50.0 1.4 3.3e-13 49.0 1.4 1.6 1 0 0 1 1 1 1 SH3 domain Ank PF00023.30 KFP19421.1 - 2.6e-13 49.7 1.4 2.1e-05 24.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP19421.1 - 1.1e-12 46.9 0.7 2.4e-05 24.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.6 KFP19421.1 - 2.5e-10 40.0 0.2 6.1e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP19421.1 - 1.2e-09 37.6 0.0 2.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 KFP19421.1 - 4.4e-08 33.2 0.2 1.4e-06 28.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ZFYVE21_C PF16696.5 KFP19422.1 - 8.7e-54 180.6 0.0 1.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Zinc finger FYVE domain-containing protein 21 C-terminus FYVE PF01363.21 KFP19422.1 - 7.4e-12 45.2 23.8 1.4e-11 44.3 23.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFP19422.1 - 8.5 6.6 20.1 29 4.9 19.0 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger Rad51 PF08423.11 KFP19423.1 - 8.5e-41 139.9 0.0 1.1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFP19423.1 - 8.4e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFP19423.1 - 1.9e-05 24.3 0.1 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 KFP19423.1 - 0.00021 20.7 0.1 0.00069 19.0 0.1 1.8 1 1 0 1 1 1 1 KaiC RNA_pol_A_CTD PF03118.15 KFP19423.1 - 0.013 15.2 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain TPX2_importin PF12214.8 KFP19424.1 - 1.4e-43 148.9 72.1 4.8e-37 127.7 10.7 7.5 5 3 2 7 7 7 4 Cell cycle regulated microtubule associated protein Aurora-A_bind PF09041.10 KFP19424.1 - 4.3e-26 90.7 0.6 1.4e-25 89.1 0.6 1.9 1 0 0 1 1 1 1 Aurora-A binding TPX2 PF06886.11 KFP19424.1 - 6.1e-14 52.0 17.8 6.1e-14 52.0 17.8 7.3 8 0 0 8 8 8 1 Targeting protein for Xklp2 (TPX2) LBP_BPI_CETP_C PF02886.17 KFP19425.1 - 8.8e-19 67.9 0.0 1e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Peptidase_A22B PF04258.13 KFP19426.1 - 2.7e-103 345.4 9.5 3.2e-103 345.2 9.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KFP19426.1 - 4.7e-05 23.0 9.1 9.7e-05 22.0 9.1 1.4 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KFP19426.1 - 0.00078 18.3 4.7 0.00078 18.3 4.7 1.6 1 1 0 1 1 1 1 Presenilin Ras PF00071.22 KFP19427.1 - 7.1e-21 74.5 0.0 8.8e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Ras family BSP PF04450.12 KFP19427.1 - 0.097 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria Roc PF08477.13 KFP19427.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFP19427.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase RabGAP-TBC PF00566.18 KFP19428.1 - 5.1e-28 98.2 0.0 7.5e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mis14 PF08641.12 KFP19428.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Pkinase PF00069.25 KFP19429.1 - 3e-72 243.2 0.3 3.5e-72 242.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19429.1 - 1.6e-20 73.5 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP19429.1 - 4.7e-08 33.2 0.0 6.4e-06 26.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP19429.1 - 0.00035 20.0 0.1 0.00058 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP19429.1 - 0.0053 15.6 0.1 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFP19429.1 - 0.0089 15.4 0.1 0.047 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 KFP19429.1 - 0.02 14.5 0.2 0.02 14.5 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.16 KFP19429.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family FTA2 PF13095.6 KFP19429.1 - 0.071 12.7 0.2 1.4 8.5 0.0 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 HLH PF00010.26 KFP19430.1 - 1.1e-18 66.9 0.3 1.5e-18 66.5 0.3 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-C2H2 PF00096.26 KFP19431.1 - 1.9e-13 50.1 25.4 0.00011 22.4 4.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP19431.1 - 9.3e-13 48.0 21.4 3e-06 27.4 0.8 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP19431.1 - 8.9e-09 35.5 22.6 0.0066 17.2 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP19431.1 - 1.2e-05 25.1 21.6 0.00011 22.0 1.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP19431.1 - 0.0011 19.2 14.2 0.15 12.4 1.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KFP19431.1 - 0.0014 18.8 10.8 0.25 11.6 5.8 2.8 1 1 2 3 3 3 2 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 KFP19431.1 - 0.002 18.2 8.3 0.015 15.4 1.7 2.4 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 KFP19431.1 - 0.0067 16.4 7.9 0.27 11.3 0.8 3.2 3 0 0 3 3 3 1 XPA protein N-terminal zf-AN1 PF01428.16 KFP19431.1 - 0.015 15.5 16.8 0.14 12.4 3.2 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger GAGA PF09237.11 KFP19431.1 - 0.032 14.1 2.6 0.13 12.1 0.6 2.4 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 KFP19431.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CpXC PF14353.6 KFP19431.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.7 1 1 2 3 3 3 0 CpXC protein zf_UBZ PF18439.1 KFP19431.1 - 0.5 10.0 8.0 13 5.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4379 PF14311.6 KFP19431.1 - 0.95 9.9 3.3 1.2 9.5 0.3 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain FYVE PF01363.21 KFP19431.1 - 1.9 8.7 13.9 1.1 9.5 6.7 2.3 1 1 1 2 2 2 0 FYVE zinc finger LIM PF00412.22 KFP19431.1 - 2.1 8.7 12.5 11 6.4 0.2 2.7 1 1 0 2 2 2 0 LIM domain zf-trcl PF13451.6 KFP19431.1 - 7.5 6.5 13.0 5.6 6.9 0.4 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain Zona_pellucida PF00100.23 KFP19433.1 - 2.2e-28 99.8 1.0 7.8e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 Zona pellucida-like domain VWA PF00092.28 KFP19434.1 - 6.9e-48 163.2 0.2 8.3e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 KFP19434.1 - 6.1e-32 109.6 60.1 3.6e-08 33.5 9.3 4.3 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP19434.1 - 1.8e-22 79.2 47.2 3.1e-06 27.3 6.1 4.3 4 0 0 4 4 4 4 Calcium-binding EGF domain cEGF PF12662.7 KFP19434.1 - 1.4e-20 72.9 31.5 6e-06 26.1 1.1 4.6 4 0 0 4 4 4 4 Complement Clr-like EGF-like VWA_2 PF13519.6 KFP19434.1 - 2.5e-19 69.9 0.1 3.6e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.27 KFP19434.1 - 7.6e-05 22.9 47.2 0.084 13.2 6.6 4.6 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.7 KFP19434.1 - 0.002 18.3 41.4 0.21 11.8 6.2 4.8 4 0 0 4 4 4 3 EGF domain zf-NF-X1 PF01422.17 KFP19434.1 - 0.066 13.3 22.0 3.2 7.9 0.9 4.8 4 0 0 4 4 4 0 NF-X1 type zinc finger Plasmod_Pvs28 PF06247.11 KFP19434.1 - 0.14 12.5 41.2 1.6 9.1 3.7 4.5 4 0 0 4 4 4 0 Pvs28 EGF domain DUF4215 PF13948.6 KFP19434.1 - 2.4 8.7 39.7 2 8.9 1.3 5.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4215) Mtp PF03821.16 KFP19435.1 - 1.8e-23 83.4 13.5 4.4e-16 59.2 4.4 2.1 1 1 1 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 KFP19435.1 - 0.00021 21.9 4.1 0.00021 21.9 4.1 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4728) MG3 PF17791.1 KFP19435.1 - 0.041 14.2 1.6 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Macroglobulin domain MG3 CBX7_C PF17218.3 KFP19436.1 - 1.1e-13 50.6 1.9 1.6e-13 50.1 1.9 1.2 1 0 0 1 1 1 1 CBX family C-terminal motif CBX7_C PF17218.3 KFP19437.1 - 4.2e-15 55.2 2.3 6.5e-15 54.6 2.3 1.3 1 0 0 1 1 1 1 CBX family C-terminal motif RBR PF17208.3 KFP19437.1 - 0.00049 20.7 10.4 0.036 14.8 2.4 2.8 2 0 0 2 2 2 2 RNA binding Region Rotamase PF00639.21 KFP19438.1 - 7.3e-22 78.2 0.0 9.2e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFP19438.1 - 1.2e-20 74.2 0.0 1.6e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KFP19438.1 - 9.2e-09 35.2 0.2 1.7e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KFP19438.1 - 0.00096 20.0 0.0 0.0012 19.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 KFP19438.1 - 0.0046 17.6 0.0 0.013 16.2 0.0 1.7 2 0 0 2 2 2 1 X8 domain LRIF1 PF15741.5 KFP19438.1 - 0.078 11.5 0.0 0.092 11.3 0.0 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 OTU PF02338.19 KFP19439.1 - 9.1e-25 87.6 0.0 1.9e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFP19439.1 - 0.0075 15.7 0.0 0.66 9.4 0.3 2.2 1 1 0 2 2 2 2 Peptidase C65 Otubain DUF4462 PF14692.6 KFP19441.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) RVT_1 PF00078.27 KFP19442.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tudor_FRX1 PF18336.1 KFP19442.1 - 0.058 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain ANF_receptor PF01094.28 KFP19443.1 - 1.5e-65 221.6 0.0 2.2e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.26 KFP19443.1 - 3.2e-59 199.1 0.0 5.1e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP19443.1 - 1.1e-44 151.3 0.3 2.4e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP19443.1 - 2.1e-23 83.0 0.0 3.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KFP19443.1 - 0.00081 19.1 0.0 0.012 15.3 0.0 2.3 2 1 0 2 2 2 1 Periplasmic binding protein Ion_trans_2 PF07885.16 KFP19443.1 - 5.7 7.0 7.4 5.2 7.1 0.1 3.3 3 0 0 3 3 3 0 Ion channel Myb_DNA-bind_5 PF13873.6 KFP19445.1 - 4.1e-23 81.2 7.1 4.1e-23 81.2 7.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KFP19445.1 - 0.00051 20.2 0.9 0.00051 20.2 0.9 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFP19445.1 - 0.0098 16.3 2.8 0.027 14.8 2.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BTB PF00651.31 KFP19446.1 - 2.1e-27 95.5 0.9 2.1e-27 95.5 0.9 2.2 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP19446.1 - 3.6e-26 91.3 3.1 3.6e-26 91.3 3.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP19446.1 - 3.6e-26 90.5 3.4 2.1e-05 24.6 0.0 6.6 3 1 3 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFP19446.1 - 1.1e-25 88.9 7.5 1.3e-06 27.8 0.0 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KFP19446.1 - 8.3e-12 44.9 0.0 0.08 13.0 0.0 5.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP19446.1 - 1.7e-09 37.7 0.0 0.82 10.0 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP19446.1 - 1.4e-06 28.0 4.8 0.11 12.6 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 KFP19446.1 - 0.0086 16.0 0.5 7.3 6.7 0.0 3.6 3 0 0 3 3 3 1 Kelch motif ACPS PF01648.20 KFP19447.1 - 6.2e-18 65.0 0.0 7.3e-16 58.3 0.0 2.4 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily VOMI PF03762.17 KFP19452.1 - 1.2e-53 181.7 2.0 1.4e-53 181.5 2.0 1.0 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) VOMI PF03762.17 KFP19453.1 - 4.1e-52 176.8 1.2 4.8e-52 176.5 1.2 1.0 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) KOG2701 PF09762.9 KFP19454.1 - 7.1 6.8 10.8 0.73 10.0 6.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) 2OG-FeII_Oxy_2 PF13532.6 KFP19455.1 - 4.8e-21 75.8 0.0 1.1e-20 74.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 KFP19455.1 - 2.9e-14 53.5 0.1 1.6e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP19455.1 - 3.7e-12 46.8 0.2 1.4e-11 44.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain RRM_1 PF00076.22 KFP19455.1 - 2.2e-09 37.0 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.6 KFP19455.1 - 9.6e-06 25.5 0.0 5.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP19455.1 - 2.3e-05 24.4 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.6 KFP19455.1 - 2.3e-05 24.2 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP19455.1 - 8.1e-05 23.3 0.0 0.00024 21.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DUF1891 PF09004.10 KFP19455.1 - 0.00053 19.5 0.4 0.002 17.7 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) 2OG-FeII_Oxy PF03171.20 KFP19455.1 - 0.03 14.8 0.0 0.076 13.5 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Methyltransf_18 PF12847.7 KFP19455.1 - 0.039 13.9 0.1 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFP19455.1 - 0.064 12.6 0.0 0.2 10.9 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KFP19455.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 KFP19455.1 - 0.15 11.7 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ELMO_CED12 PF04727.13 KFP19457.1 - 2.7e-46 157.9 0.2 4.6e-46 157.2 0.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Ras PF00071.22 KFP19459.1 - 9.9e-29 100.0 0.0 1.2e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP19459.1 - 1.2e-05 25.5 0.0 2.5e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP19459.1 - 0.049 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family zf-C2H2_3 PF13878.6 KFP19459.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Thiolase_N PF00108.23 KFP19460.1 - 1.2e-95 319.7 3.4 1.8e-95 319.2 3.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP19460.1 - 1.1e-46 157.5 2.0 4.4e-46 155.5 1.2 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP19460.1 - 2.7e-05 23.9 8.9 3e-05 23.8 4.3 2.8 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KFP19460.1 - 0.02 15.0 0.7 0.14 12.3 0.0 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_transf_90 PF05686.12 KFP19461.1 - 2.4e-85 286.9 0.2 3.1e-85 286.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KFP19461.1 - 0.00097 19.5 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Filamin PF00630.19 KFP19461.1 - 0.0031 18.3 0.0 0.0059 17.4 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat DEAD PF00270.29 KFP19463.1 - 2.3e-47 161.0 0.8 1.3e-46 158.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP19463.1 - 1.9e-25 89.4 0.1 2.6e-24 85.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFP19463.1 - 4.5e-18 65.2 0.3 1.1e-17 64.0 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFP19463.1 - 2.3e-10 40.7 0.0 2.3e-10 40.7 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 KFP19465.1 - 8e-16 57.9 0.4 2.1e-15 56.6 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KFP19465.1 - 1.5e-05 24.7 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP19465.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BORG_CEP PF14957.6 KFP19466.1 - 1.1e-07 33.0 0.6 1.5e-07 32.6 0.6 1.4 1 1 0 1 1 1 1 Cdc42 effector GFRP PF06399.13 KFP19467.1 - 3.1e-34 116.7 0.0 3.3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) TPR_11 PF13414.6 KFP19468.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.6 KFP19468.1 - 0.25 11.8 0.8 1.1 9.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad51 PF08423.11 KFP19469.1 - 6.5e-130 431.9 0.0 7.9e-130 431.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFP19469.1 - 2e-11 43.8 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFP19469.1 - 2.2e-09 37.2 0.1 3.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KFP19469.1 - 6e-09 36.4 0.2 2.4e-08 34.5 0.3 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KFP19469.1 - 2.2e-05 23.9 1.7 0.00013 21.5 1.1 2.4 2 1 0 2 2 2 1 KaiC HHH PF00633.23 KFP19469.1 - 0.017 15.0 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AAA_22 PF13401.6 KFP19469.1 - 0.019 15.3 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFP19469.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KFP19469.1 - 0.087 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Knl1_RWD_C PF18210.1 KFP19470.1 - 6.1e-46 154.9 0.0 1.7e-45 153.5 0.0 1.8 1 0 0 1 1 1 1 Knl1 RWD C-terminal domain SOGA PF11365.8 KFP19470.1 - 0.0022 19.1 11.0 0.26 12.4 0.5 3.5 2 1 0 2 2 2 2 Protein SOGA Spc7 PF08317.11 KFP19470.1 - 0.0034 16.3 17.5 0.025 13.5 17.4 2.7 1 1 0 1 1 1 1 Spc7 kinetochore protein AAA_15 PF13175.6 KFP19470.1 - 0.0054 16.5 1.4 0.0079 15.9 1.4 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF2730 PF10805.8 KFP19470.1 - 0.84 9.8 4.4 2.3 8.3 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) PseudoU_synth_2 PF00849.22 KFP19472.1 - 7.9e-31 107.3 0.2 1.3e-30 106.6 0.2 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase PCMT PF01135.19 KFP19473.1 - 4.7e-81 271.5 0.0 5.5e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFP19473.1 - 1.6e-06 28.7 0.0 2.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP19473.1 - 3.8e-06 26.8 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP19473.1 - 2.7e-05 24.7 0.0 4.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP19473.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KFP19473.1 - 0.00048 19.9 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KFP19473.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KFP19473.1 - 0.048 13.5 0.0 0.087 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFP19473.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFP19473.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KFP19473.1 - 0.14 13.2 0.0 0.26 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CCDC32 PF14989.6 KFP19474.1 - 5.2e-60 201.9 0.2 6.2e-60 201.6 0.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 BAH PF01426.18 KFP19475.1 - 6.9e-15 55.0 0.0 2.9e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 BAH domain Acyl-CoA_dh_1 PF00441.24 KFP19476.1 - 1.2e-38 132.7 0.1 1.8e-38 132.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFP19476.1 - 6.9e-35 120.1 0.0 1.2e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFP19476.1 - 1.4e-26 92.5 0.0 2.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFP19476.1 - 6.6e-10 39.4 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SIX1_SD PF16878.5 KFP19477.1 - 1.4e-13 51.3 0.7 3.1e-13 50.2 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP19477.1 - 1.7e-08 34.1 2.9 1.7e-08 34.1 2.9 2.1 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 KFP19477.1 - 7.7e-07 28.9 1.1 3.4e-06 26.9 0.4 2.2 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_1 PF01527.20 KFP19477.1 - 0.023 15.0 0.4 0.051 13.9 0.4 1.6 1 0 0 1 1 1 0 Transposase CENP-B_N PF04218.13 KFP19477.1 - 0.15 11.7 0.2 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain 14-3-3 PF00244.20 KFP19478.1 - 3.3e-93 311.3 6.7 3.7e-93 311.1 6.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3504 PF12012.8 KFP19478.1 - 0.08 12.9 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) SSF PF00474.17 KFP19479.1 - 2.8e-167 556.7 27.0 4.5e-167 556.0 27.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family G-alpha PF00503.20 KFP19481.1 - 3.9e-119 398.0 1.0 4.5e-119 397.7 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP19481.1 - 1.1e-16 60.8 0.3 7.7e-11 41.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP19481.1 - 0.00021 20.7 4.3 0.016 14.6 0.4 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP19481.1 - 0.0031 17.6 0.3 1.2 9.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase TniB PF05621.11 KFP19481.1 - 0.012 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KFP19481.1 - 0.013 15.7 1.4 1.8 8.8 0.2 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFP19481.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2951 PF11166.8 KFP19481.1 - 0.067 13.4 0.3 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) AAA_16 PF13191.6 KFP19481.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 KFP19482.1 - 4.1e-45 153.3 0.3 5.6e-45 152.8 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP19482.1 - 2.4e-30 105.2 0.0 4.4e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP19482.1 - 3.1e-15 56.1 0.0 4.3e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP19482.1 - 2.6e-07 30.7 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP19482.1 - 6.3e-05 22.4 0.0 8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP19482.1 - 0.0016 18.0 0.0 0.066 12.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KFP19482.1 - 0.0087 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 KFP19482.1 - 0.035 13.6 0.0 0.34 10.4 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KFP19482.1 - 0.041 13.9 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP19482.1 - 0.092 12.7 0.0 3.5 7.5 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase DUF3177 PF11375.8 KFP19482.1 - 0.13 12.0 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) RhoGAP PF00620.27 KFP19483.1 - 1.8e-49 167.5 0.4 1.6e-48 164.4 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain Bcr-Abl_Oligo PF09036.10 KFP19483.1 - 2.9e-37 126.5 1.2 2.9e-37 126.5 1.2 2.7 2 0 0 2 2 2 1 Bcr-Abl oncoprotein oligomerisation domain RhoGEF PF00621.20 KFP19483.1 - 2.2e-34 119.3 0.9 4.9e-34 118.1 0.9 1.6 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.30 KFP19483.1 - 3e-07 30.7 0.0 9.6e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFP19483.1 - 0.0048 17.4 3.0 0.015 15.8 0.7 2.9 2 1 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 KFP19483.1 - 0.02 14.8 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 PH domain CH PF00307.31 KFP19484.1 - 1.1e-20 73.8 0.3 5.3e-20 71.6 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP19484.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain TMF_DNA_bd PF12329.8 KFP19484.1 - 0.013 15.5 1.8 0.013 15.5 1.8 9.7 8 3 3 11 11 11 0 TATA element modulatory factor 1 DNA binding 7tm_1 PF00001.21 KFP19487.1 - 7.5e-47 159.9 16.3 8.8e-47 159.6 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP19487.1 - 2.9e-08 33.8 9.5 3.9e-08 33.4 9.5 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP19487.1 - 2.6e-07 30.3 20.4 2.3e-06 27.2 20.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP19487.1 - 9e-07 28.8 15.6 9e-07 28.8 15.6 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CN_hydrolase PF00795.22 KFP19488.1 - 3.7e-61 206.8 0.0 4.5e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Guanylate_cyc_2 PF09778.9 KFP19489.1 - 4.4e-94 313.7 3.1 5e-94 313.6 3.1 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 KFP19489.1 - 1e-08 35.8 0.1 4.1e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 KFP19489.1 - 6.3e-07 29.5 0.0 0.027 14.4 0.0 2.5 2 1 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 DUF3335 PF11814.8 KFP19489.1 - 5.1e-05 22.9 0.2 0.029 13.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 KFP19489.1 - 0.00042 20.1 0.1 0.0066 16.3 0.1 2.4 2 1 0 2 2 2 1 Peptidase C39 family PyocinActivator PF11112.8 KFP19489.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN TMEM52 PF14979.6 KFP19489.1 - 0.23 11.4 6.0 0.43 10.5 6.0 1.4 1 0 0 1 1 1 0 Transmembrane 52 LSM PF01423.22 KFP19490.1 - 6.9e-16 57.7 0.2 9.5e-16 57.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.18 KFP19490.1 - 0.15 12.4 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Kringle domain G_glu_transpept PF01019.21 KFP19491.1 - 2.6e-178 594.0 0.0 2.9e-178 593.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 KFP19492.1 - 8.9e-136 453.6 0.0 1e-135 453.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SLC3A2_N PF16028.5 KFP19492.1 - 0.18 11.3 0.2 0.41 10.2 0.2 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus mit_SMPDase PF14724.6 KFP19493.1 - 0 1497.2 4.3 0 1497.0 4.3 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase Ground-like PF04155.18 KFP19493.1 - 0.14 12.8 0.1 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Ground-like domain Med15 PF09606.10 KFP19494.1 - 6.5e-183 610.5 149.5 8.5e-183 610.1 149.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.13 KFP19494.1 - 0.14 11.2 36.1 0.25 10.4 36.1 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SH3_2 PF07653.17 KFP19495.1 - 2.3e-24 84.8 0.2 9e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP19495.1 - 2.5e-21 75.0 0.3 4.2e-16 58.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.24 KFP19495.1 - 8.8e-21 73.8 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 KFP19495.1 - 8.5e-15 54.4 1.9 1e-07 31.7 0.1 2.9 4 0 0 4 4 4 2 Variant SH3 domain hSH3 PF14603.6 KFP19495.1 - 0.01 16.3 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain T-box PF00907.22 KFP19496.1 - 1.8e-80 269.6 0.1 2.4e-80 269.1 0.1 1.2 1 0 0 1 1 1 1 T-box MEF2_binding PF09047.10 KFP19497.1 - 1.6e-22 79.0 7.1 3.9e-22 77.8 7.1 1.7 1 0 0 1 1 1 1 MEF2 binding TPR_2 PF07719.17 KFP19497.1 - 3.9e-09 35.9 21.5 0.26 11.5 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19497.1 - 2e-06 27.4 21.7 0.071 13.0 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP19497.1 - 0.00022 20.9 4.5 0.027 14.1 0.0 4.6 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 KFP19497.1 - 0.00056 20.1 13.6 4.5 7.9 0.0 7.1 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19497.1 - 0.0022 18.1 22.1 0.47 10.8 0.1 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat FAT PF02259.23 KFP19497.1 - 0.0034 16.7 0.1 0.029 13.6 0.0 2.4 2 0 0 2 2 2 1 FAT domain TPR_9 PF13371.6 KFP19497.1 - 0.023 14.8 0.3 0.43 10.8 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19497.1 - 0.13 12.9 8.7 44 4.8 0.0 5.6 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19497.1 - 0.14 12.5 11.5 9.3 6.6 0.3 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19497.1 - 0.25 11.5 3.7 4.7 7.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFP19497.1 - 0.5 11.2 2.1 27 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19497.1 - 2.2 9.3 9.8 27 5.9 0.3 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat GST_C PF00043.25 KFP19499.1 - 1.9e-07 31.2 0.0 4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFP19499.1 - 8.1e-05 22.7 0.0 0.00029 21.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP19499.1 - 0.00014 21.8 0.0 0.00048 20.1 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP19499.1 - 0.00025 21.3 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFP19499.1 - 0.0017 18.7 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP19500.1 - 3.3e-07 30.4 0.0 6.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFP19500.1 - 3.6e-07 30.4 0.0 1.4e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP19500.1 - 1.8e-05 24.9 0.0 8.4e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFP19500.1 - 2.2e-05 24.8 0.0 4.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFP19500.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP19500.1 - 0.0007 19.9 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SVIP PF15811.5 KFP19500.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Small VCP/p97-interacting protein GST_C_5 PF16865.5 KFP19500.1 - 0.16 12.5 0.0 0.38 11.4 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 KFP19501.1 - 6.6e-42 143.2 0.1 1.2e-41 142.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP19501.1 - 1.2e-27 96.4 0.2 7.6e-26 90.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP19501.1 - 2.5e-11 43.9 0.4 5.8e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFP19501.1 - 0.0017 18.0 0.0 0.0017 18.0 0.0 1.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase T4SS-DNA_transf PF02534.14 KFP19501.1 - 0.0032 16.4 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_22 PF13401.6 KFP19501.1 - 0.012 15.9 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain IMS_HHH PF11798.8 KFP19501.1 - 0.033 14.5 0.1 0.089 13.2 0.1 1.7 1 0 0 1 1 1 0 IMS family HHH motif AAA_19 PF13245.6 KFP19501.1 - 0.047 14.0 0.0 0.18 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Tim54 PF11711.8 KFP19501.1 - 2.8 6.6 6.4 4.5 6.0 6.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MIF PF01187.18 KFP19502.1 - 1.6e-51 173.4 0.0 1.7e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Sugar_tr PF00083.24 KFP19503.1 - 3e-36 125.3 3.4 3.4e-36 125.1 3.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP19503.1 - 3.7e-07 29.4 5.2 4.9e-07 29.0 5.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YukC PF10140.9 KFP19503.1 - 0.062 12.1 0.3 0.094 11.5 0.3 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kelch_2 PF07646.15 KFP19503.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Sugar_tr PF00083.24 KFP19504.1 - 3.5e-48 164.6 4.3 4.2e-48 164.3 4.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP19504.1 - 4.3e-21 75.2 0.5 5.6e-21 74.8 0.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFP19504.1 - 0.16 10.5 4.9 0.06 11.9 2.2 1.7 2 0 0 2 2 2 0 MFS/sugar transport protein MORN PF02493.20 KFP19505.1 - 3.3e-29 99.0 36.3 7.6e-05 22.4 0.4 6.6 6 0 0 6 6 6 6 MORN repeat PHD_4 PF16866.5 KFP19506.1 - 1e-26 92.8 9.6 1e-26 92.8 9.6 2.6 2 0 0 2 2 1 1 PHD-finger zf-CXXC PF02008.20 KFP19506.1 - 1.4e-14 53.8 21.5 1.4e-14 53.8 21.5 3.1 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.33 KFP19506.1 - 2.1e-13 49.8 6.9 1.1e-12 47.5 1.7 2.8 2 0 0 2 2 2 1 F-box domain JHD PF17811.1 KFP19506.1 - 9.5e-11 42.2 8.2 2.4e-10 40.9 0.1 3.4 3 0 0 3 3 3 1 Jumonji helical domain F-box-like PF12937.7 KFP19506.1 - 7.2e-09 35.4 5.8 2e-08 34.0 5.8 1.8 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.6 KFP19506.1 - 4.3e-07 29.9 2.3 2.1e-06 27.7 0.0 2.8 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 KFP19506.1 - 6.5e-05 23.3 0.3 6.5e-05 23.3 0.3 3.5 3 1 0 3 3 2 1 JmjC domain, hydroxylase LRR_6 PF13516.6 KFP19506.1 - 0.00064 19.6 8.4 31 5.0 0.3 7.1 8 0 0 8 8 8 0 Leucine Rich repeat PHD PF00628.29 KFP19506.1 - 0.0061 16.4 8.1 0.0061 16.4 8.1 3.0 2 0 0 2 2 1 1 PHD-finger LRR_4 PF12799.7 KFP19506.1 - 0.096 13.1 7.8 6.3 7.4 0.4 4.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP19506.1 - 0.76 9.6 4.8 55 3.6 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat ANAPC5 PF12862.7 KFP19507.1 - 4.7e-31 106.7 2.4 4.7e-31 106.7 2.4 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KFP19507.1 - 1.3e-09 38.2 10.6 0.00011 22.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP19507.1 - 3.3e-05 24.3 9.7 0.15 12.6 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFP19507.1 - 0.00018 21.3 6.5 0.019 14.8 2.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19507.1 - 0.00029 20.6 6.6 0.091 12.8 0.8 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19507.1 - 0.0028 17.7 13.2 0.7 10.1 2.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19507.1 - 0.018 15.8 6.7 72 4.6 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PriA_C PF18074.1 KFP19507.1 - 0.088 13.6 0.6 0.71 10.7 0.6 2.7 1 1 0 1 1 1 0 Primosomal protein N C-terminal domain TPR_8 PF13181.6 KFP19507.1 - 0.46 10.8 7.1 23 5.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19507.1 - 1.3 8.9 7.8 2.2 8.2 1.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFP19507.1 - 2.4 9.0 7.8 1.2 10.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19507.1 - 7.9 7.1 7.0 96 3.7 0.4 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KFP19508.1 - 1.2e-65 221.5 0.0 8.6e-65 218.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19508.1 - 4.8e-34 117.8 0.0 4.5e-32 111.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP19508.1 - 1e-08 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP19508.1 - 4.4e-05 22.4 0.0 7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFP19508.1 - 0.0068 16.0 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP19508.1 - 0.024 14.6 0.2 0.88 9.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFP19508.1 - 0.18 10.8 0.4 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 P2X_receptor PF00864.19 KFP19509.1 - 6.7e-158 525.6 4.4 7.5e-158 525.4 4.4 1.0 1 0 0 1 1 1 1 ATP P2X receptor IFT81_CH PF18383.1 KFP19511.1 - 1.8e-50 170.3 0.1 1.8e-50 170.3 0.1 3.3 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 KFP19511.1 - 0.00036 19.5 20.4 0.00036 19.5 20.4 5.2 1 1 3 5 5 5 3 Spc7 kinetochore protein Frankia_peptide PF14407.6 KFP19511.1 - 0.63 10.1 4.9 1.2 9.2 0.1 3.5 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF948 PF06103.11 KFP19511.1 - 0.83 9.9 16.2 0.21 11.9 0.5 4.3 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Osmo_CC PF08946.10 KFP19511.1 - 6.1 7.2 16.4 16 5.8 1.1 5.5 4 0 0 4 4 4 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 KFP19511.1 - 8.4 6.9 16.7 11 6.6 0.6 5.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein E1-E2_ATPase PF00122.20 KFP19512.1 - 1.2e-54 184.6 7.2 1.1e-53 181.4 0.4 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP19512.1 - 2.3e-45 154.6 2.9 2.3e-45 154.6 2.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFP19512.1 - 7.1e-21 74.1 0.3 1.4e-20 73.2 0.3 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP19512.1 - 1.6e-18 67.8 0.1 3.5e-17 63.4 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFP19512.1 - 3.6e-17 61.8 1.4 2.2e-16 59.3 0.2 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFP19512.1 - 1.7e-05 24.7 0.6 1.7e-05 24.7 0.6 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP19512.1 - 0.0018 18.7 0.1 0.01 16.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P21-Arc PF04062.14 KFP19513.1 - 9.1e-82 273.3 0.2 1e-81 273.1 0.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ATP_bind_1 PF03029.17 KFP19514.1 - 2.1e-68 230.7 0.6 2.4e-68 230.5 0.6 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SUI1 PF01253.22 KFP19515.1 - 4e-17 62.5 0.1 7e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 TMF_TATA_bd PF12325.8 KFP19516.1 - 0.01 16.0 11.2 0.01 16.0 11.2 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CobA_CobO_BtuR PF02572.15 KFP19516.1 - 0.19 12.0 10.6 0.36 11.1 1.5 3.1 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF3800 PF12686.7 KFP19516.1 - 0.39 11.3 2.9 3.4 8.3 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) HAP1_N PF04849.13 KFP19516.1 - 0.4 9.8 50.5 0.029 13.6 22.5 3.1 1 1 2 3 3 3 0 HAP1 N-terminal conserved region ANTH PF07651.16 KFP19517.1 - 1e-63 215.0 10.7 4.5e-63 212.8 0.1 3.3 2 1 0 2 2 2 1 ANTH domain HIP1_clath_bdg PF16515.5 KFP19517.1 - 8.4e-31 106.5 23.0 8.4e-31 106.5 23.0 5.7 5 1 1 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 I_LWEQ PF01608.17 KFP19517.1 - 4.6e-22 78.9 1.7 4.6e-22 78.9 1.7 4.8 3 2 1 4 4 4 1 I/LWEQ domain Laminin_II PF06009.12 KFP19517.1 - 0.1 12.6 0.1 0.1 12.6 0.1 4.8 2 1 5 7 7 7 0 Laminin Domain II Golgin_A5 PF09787.9 KFP19517.1 - 0.36 10.3 67.2 0.26 10.7 14.7 4.1 2 1 2 4 4 4 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KFP19517.1 - 0.37 8.2 58.7 0.021 12.4 52.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Nup54_57_C PF18570.1 KFP19517.1 - 0.54 9.9 4.1 1.1 9.0 0.1 3.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Mod_r PF07200.13 KFP19518.1 - 4.8e-33 114.3 7.8 6.2e-33 114.0 7.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Cortex-I_coil PF09304.10 KFP19518.1 - 0.67 10.2 7.7 2.3 8.5 7.7 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil ABC_membrane PF00664.23 KFP19519.1 - 1.7e-58 198.4 16.5 3.1e-58 197.6 16.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP19519.1 - 1e-34 120.0 0.0 2.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP19519.1 - 1.2e-10 41.2 1.0 3.1e-07 30.0 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KFP19519.1 - 0.00036 20.5 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KFP19519.1 - 0.00036 21.0 0.0 0.00093 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane_3 PF13748.6 KFP19519.1 - 0.00039 19.7 3.6 0.00078 18.8 3.6 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 KFP19519.1 - 0.00064 20.0 0.0 0.003 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFP19519.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MCU PF04678.13 KFP19519.1 - 0.0087 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF4191 PF13829.6 KFP19519.1 - 0.049 13.0 0.1 0.049 13.0 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4191) AAA_15 PF13175.6 KFP19519.1 - 0.12 12.1 0.4 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF2448 PF10476.9 KFP19519.1 - 0.14 12.0 0.8 1.9 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2448) SbcCD_C PF13558.6 KFP19519.1 - 0.16 12.2 0.6 2.6 8.3 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFP19519.1 - 0.18 12.3 0.1 0.62 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFP19519.1 - 0.2 12.1 0.4 12 6.3 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP19519.1 - 0.21 12.1 1.0 7.4 7.1 0.0 2.8 2 1 1 3 3 2 0 AAA domain Integrase_H2C2 PF17921.1 KFP19520.1 - 3.5e-17 62.2 0.6 5e-17 61.8 0.6 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KFP19520.1 - 1.9e-06 28.0 0.5 4.2e-06 26.9 0.5 1.5 1 0 0 1 1 1 1 H2C2 zinc finger SR-25 PF10500.9 KFP19522.1 - 1.2e-88 296.5 65.4 1.9e-88 295.9 65.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 KFP19522.1 - 0.4 9.2 34.9 0.51 8.8 34.9 1.3 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 KFP19522.1 - 3.8 5.2 34.0 4.6 4.9 34.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RF-1 PF00472.20 KFP19523.1 - 1.9e-23 82.6 3.6 2.2e-23 82.4 3.6 1.1 1 0 0 1 1 1 1 RF-1 domain DUF2098 PF09871.9 KFP19523.1 - 0.097 13.0 2.8 0.13 12.6 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Nucleoporin_FG2 PF15967.5 KFP19523.1 - 0.24 9.9 0.1 0.27 9.7 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region CDK2AP PF09806.9 KFP19524.1 - 1.1e-09 38.7 0.0 1.5e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AAA_34 PF13872.6 KFP19525.1 - 1.3e-142 474.1 0.0 2e-142 473.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KFP19525.1 - 2.2e-125 417.8 0.0 3.4e-125 417.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KFP19525.1 - 8.7e-08 32.4 0.1 6.7e-07 29.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP19525.1 - 0.096 13.0 0.1 0.38 11.1 0.1 2.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SET PF00856.28 KFP19526.1 - 1.5e-19 71.0 1.8 4.5e-19 69.4 0.1 2.3 2 1 0 2 2 2 1 SET domain ERp29 PF07749.12 KFP19526.1 - 0.12 13.2 0.7 14 6.7 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SRP-alpha_N PF04086.13 KFP19526.1 - 0.48 10.3 8.6 0.61 10.0 8.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RRM_1 PF00076.22 KFP19527.1 - 2e-17 62.8 0.0 3.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.8 KFP19527.1 - 0.093 12.9 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 DNA ligase IV EMP24_GP25L PF01105.24 KFP19528.1 - 2.2e-39 135.3 0.1 2.5e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TerD PF02342.18 KFP19528.1 - 0.0005 19.6 0.2 0.00061 19.3 0.2 1.1 1 0 0 1 1 1 1 TerD domain Innexin PF00876.18 KFP19528.1 - 0.033 13.5 0.3 0.038 13.3 0.3 1.1 1 0 0 1 1 1 0 Innexin SdrD_B PF17210.3 KFP19528.1 - 0.036 14.3 0.3 0.089 13.0 0.3 1.7 1 1 0 1 1 1 0 SdrD B-like domain DUF1104 PF06518.11 KFP19528.1 - 0.12 12.8 1.6 0.22 11.9 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DEAD PF00270.29 KFP19529.1 - 7.5e-39 133.3 0.0 1.7e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP19529.1 - 1.6e-23 83.1 0.0 3.3e-22 78.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFP19529.1 - 2.2e-22 79.0 0.7 5.8e-22 77.7 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFP19529.1 - 6.3e-06 26.3 1.0 4.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 KFP19529.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.6 KFP19529.1 - 0.024 14.9 0.1 0.079 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.6 KFP19529.1 - 0.054 13.7 1.2 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain SHOCT PF09851.9 KFP19529.1 - 0.084 12.6 0.2 0.084 12.6 0.2 3.0 3 0 0 3 3 3 0 Short C-terminal domain SurA_N_3 PF13624.6 KFP19529.1 - 0.24 11.2 3.3 0.5 10.1 3.3 1.4 1 0 0 1 1 1 0 SurA N-terminal domain RNA_pol_Rpc4 PF05132.14 KFP19529.1 - 0.84 10.1 5.7 1.6 9.1 5.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 IF-2B PF01008.17 KFP19530.1 - 3.5e-70 236.4 0.0 4.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Tfb4 PF03850.14 KFP19531.1 - 1.5e-101 339.6 0.4 1.7e-101 339.4 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Baculo_IE-1 PF05290.11 KFP19531.1 - 2.5 8.0 8.9 0.74 9.8 4.9 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF1619 PF07773.11 KFP19532.1 - 7.6e-58 196.9 3.4 3.1e-55 188.3 3.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) CCDC92 PF14916.6 KFP19533.1 - 3.1e-24 84.5 8.6 1.7e-22 78.9 1.8 2.6 2 0 0 2 2 2 2 Coiled-coil domain of unknown function Angiomotin_C PF12240.8 KFP19533.1 - 0.002 17.7 8.7 0.0023 17.5 7.4 1.7 1 1 1 2 2 2 1 Angiomotin C terminal Sigma54_DBD PF04552.13 KFP19533.1 - 0.0062 16.2 2.5 0.011 15.5 2.5 1.3 1 0 0 1 1 1 1 Sigma-54, DNA binding domain CENP-F_leu_zip PF10473.9 KFP19533.1 - 0.069 13.2 24.3 0.5 10.4 0.5 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 KFP19533.1 - 0.1 12.1 7.8 0.14 11.7 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KFP19533.1 - 0.19 11.8 20.5 0.54 10.3 0.1 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mei5 PF10376.9 KFP19533.1 - 0.26 11.1 15.5 0.094 12.6 11.7 1.9 1 1 1 2 2 2 0 Double-strand recombination repair protein DUF3584 PF12128.8 KFP19533.1 - 0.32 8.5 12.1 0.42 8.1 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.6 KFP19533.1 - 0.34 10.3 17.5 0.65 9.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 KFP19533.1 - 0.51 9.6 5.8 0.98 8.7 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KFP19533.1 - 0.83 8.7 17.5 6.8 5.7 17.5 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 KFP19533.1 - 0.98 9.4 13.9 1.8 8.6 3.2 3.3 1 1 1 3 3 3 0 FlxA-like protein Syntaxin-6_N PF09177.11 KFP19533.1 - 1.7 9.3 8.4 45 4.7 8.5 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fez1 PF06818.15 KFP19533.1 - 1.8 9.0 16.5 1.9 8.9 13.7 2.1 1 1 1 2 2 2 0 Fez1 Nup54 PF13874.6 KFP19533.1 - 2.5 8.2 16.1 0.2 11.8 5.5 2.3 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 KxDL PF10241.9 KFP19533.1 - 3.9 7.8 15.1 1.7 9.0 7.4 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein V_ATPase_I PF01496.19 KFP19533.1 - 4.6 5.0 8.1 6 4.7 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.12 KFP19533.1 - 5.1 7.5 15.1 32 4.8 1.0 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 KFP19533.1 - 7.3 6.0 18.0 5.5 6.4 0.9 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Lebercilin PF15619.6 KFP19533.1 - 7.7 6.1 24.7 58 3.3 24.8 2.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 KFP19533.1 - 9.9 4.0 9.0 13 3.6 9.0 1.1 1 0 0 1 1 1 0 Prominin FAM101 PF15068.6 KFP19534.1 - 1.1e-68 231.3 1.8 1.2e-68 231.1 1.8 1.0 1 0 0 1 1 1 1 FAM101 family CD36 PF01130.21 KFP19536.1 - 2.7e-147 491.1 3.2 3e-147 491.0 3.2 1.0 1 0 0 1 1 1 1 CD36 family HA2 PF04408.23 KFP19538.1 - 3e-24 85.4 0.1 3e-24 85.4 0.1 3.1 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP19538.1 - 4.7e-24 84.6 0.0 1.1e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFP19538.1 - 1.6e-11 44.3 0.1 1.6e-11 44.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP19538.1 - 3.7e-11 43.4 0.9 5.2e-09 36.4 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFP19538.1 - 7.4e-07 29.5 0.1 4.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP19538.1 - 2.3e-05 24.2 0.0 6.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP19538.1 - 4.1e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KFP19538.1 - 0.0029 17.6 1.5 0.04 13.9 0.0 3.0 3 0 0 3 3 3 1 Flavivirus DEAD domain T2SSE PF00437.20 KFP19538.1 - 0.0055 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 KFP19538.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 KaiC ResIII PF04851.15 KFP19538.1 - 0.014 15.4 6.2 0.069 13.1 0.3 3.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFP19538.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFP19538.1 - 0.11 13.1 4.1 0.56 10.7 0.1 2.8 2 1 1 3 3 3 0 ABC transporter Roc PF08477.13 KFP19538.1 - 0.13 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BSP_II PF05432.11 KFP19538.1 - 0.9 9.2 11.9 2.1 7.9 11.9 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AAA_11 PF13086.6 KFP19538.1 - 3.7 7.3 15.4 7.7 6.2 0.0 3.4 2 1 1 3 3 3 0 AAA domain BRI3BP PF14965.6 KFP19539.1 - 1.3e-65 220.3 0.9 1.5e-65 220.1 0.9 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 CLZ PF16526.5 KFP19539.1 - 0.033 14.5 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MgtE PF01769.16 KFP19539.1 - 0.034 14.5 2.8 0.048 14.1 2.8 1.4 1 0 0 1 1 1 0 Divalent cation transporter AMP-binding PF00501.28 KFP19540.1 - 1.9e-42 145.3 0.0 2.8e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFP19540.1 - 1.2e-10 41.1 2.2 1.2e-10 41.1 2.2 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Profilin PF00235.19 KFP19540.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 Profilin TMEM132D_N PF15705.5 KFP19541.1 - 9.8e-57 190.4 0.0 1.6e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132 PF16070.5 KFP19541.1 - 1.2e-16 61.0 3.3 2.1e-16 60.2 3.3 1.4 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_N PF15705.5 KFP19545.1 - 1.1e-58 196.7 0.1 1.3e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term TMEM132 PF16070.5 KFP19546.1 - 2.5e-128 428.3 1.2 3.2e-128 427.9 1.2 1.1 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFP19546.1 - 1.1e-37 127.7 0.0 2.1e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PTR2 PF00854.21 KFP19547.1 - 2.6e-113 378.8 6.8 3e-113 378.6 6.8 1.0 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KFP19547.1 - 5.8e-10 38.6 11.8 1.1e-09 37.7 11.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Glycos_transf_1 PF00534.20 KFP19548.1 - 2e-18 66.6 0.0 2.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP19548.1 - 2.9e-15 56.9 0.0 4.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFP19548.1 - 3.7e-08 33.6 0.0 8.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2773 PF10971.8 KFP19548.1 - 0.12 12.5 0.1 0.82 9.8 0.0 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2773) TMEM132 PF16070.5 KFP19549.1 - 8.7e-156 518.6 2.2 1.2e-155 518.2 2.2 1.2 1 0 0 1 1 1 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KFP19549.1 - 1.9e-36 123.7 0.0 4.3e-36 122.6 0.0 1.7 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132D_N PF15705.5 KFP19550.1 - 2.9e-36 124.2 0.3 3.3e-36 124.0 0.3 1.0 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term VPS9 PF02204.18 KFP19551.1 - 7.5e-23 80.7 0.1 1.6e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.23 KFP19551.1 - 1.6e-12 47.9 0.1 4.2e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.24 KFP19551.1 - 0.0017 18.4 0.0 0.0069 16.5 0.0 2.1 2 0 0 2 2 2 1 SH2 domain FERM_f0 PF16511.5 KFP19551.1 - 0.0079 16.5 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM VRP3 PF03536.15 KFP19551.1 - 0.018 14.6 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein RelB PF04221.12 KFP19551.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin Na_Ca_ex PF01699.24 KFP19552.1 - 2.3e-58 196.4 40.4 4.6e-30 104.6 14.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SPC25 PF06703.11 KFP19552.1 - 0.0046 16.8 2.5 0.028 14.2 0.1 2.6 2 0 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) CENP-B_dimeris PF09026.10 KFP19552.1 - 0.017 15.5 10.7 0.039 14.3 10.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 KFP19552.1 - 0.029 14.6 7.2 0.043 14.1 7.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Herpes_LMP1 PF05297.11 KFP19552.1 - 0.032 13.5 0.3 0.032 13.5 0.3 3.1 3 0 0 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) RXT2_N PF08595.11 KFP19552.1 - 0.041 13.9 2.4 0.073 13.1 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 KFP19552.1 - 0.047 13.0 1.6 0.06 12.7 1.6 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KFP19552.1 - 0.093 12.0 8.4 0.14 11.5 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KFP19552.1 - 0.14 11.7 5.6 0.22 11.1 5.6 1.2 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KFP19552.1 - 0.27 11.0 8.1 0.4 10.4 8.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 KFP19552.1 - 0.59 9.2 5.2 1.1 8.3 5.2 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein p53-inducible11 PF14936.6 KFP19552.1 - 1.9 8.5 7.2 0.56 10.2 3.4 2.0 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 WRNPLPNID PF15017.6 KFP19552.1 - 2.6 9.0 11.0 5.2 8.0 11.0 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DNA_pol_phi PF04931.13 KFP19552.1 - 5.7 4.9 15.0 8.4 4.4 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ac76 PF05814.11 KFP19552.1 - 6.1 6.9 8.3 0.69 10.0 1.2 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) FAM176 PF14851.6 KFP19552.1 - 6.3 6.5 6.5 23 4.6 6.1 2.0 2 0 0 2 2 2 0 FAM176 family TRAP_alpha PF03896.16 KFP19552.1 - 7.9 5.6 6.5 3.1 6.9 3.7 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KFP19552.1 - 7.9 4.6 10.6 11 4.1 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family HAT PF02184.16 KFP19553.1 - 2.4e-37 126.6 68.8 5.1e-16 58.3 0.5 14.4 13 2 0 13 13 13 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFP19553.1 - 1.8e-15 56.3 21.7 0.19 12.6 0.4 10.9 7 4 5 12 12 11 5 Tetratricopeptide repeat Suf PF05843.14 KFP19553.1 - 4.4e-10 40.0 40.2 0.00018 21.6 5.7 5.8 2 1 3 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KFP19553.1 - 1.2e-08 35.3 6.2 0.0098 16.4 0.0 7.6 7 1 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP19553.1 - 5.4e-08 32.7 5.5 0.0013 18.9 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP19553.1 - 2.2e-06 28.2 1.9 5.8 7.6 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP19553.1 - 0.00018 21.7 5.2 6 7.2 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19553.1 - 0.00021 21.2 5.4 5.5 7.5 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFP19553.1 - 0.00056 19.1 30.0 0.0093 15.1 3.5 5.7 1 1 4 5 5 5 4 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 KFP19553.1 - 0.009 16.0 34.2 0.19 11.7 3.9 7.4 5 3 0 5 5 5 1 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 KFP19553.1 - 0.01 15.9 1.8 0.01 15.9 1.8 6.5 5 4 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.17 KFP19553.1 - 0.14 12.3 23.6 2.2 8.6 0.3 8.5 11 0 0 11 11 9 0 Tetratricopeptide repeat DUF4821 PF16092.5 KFP19554.1 - 9e-104 346.8 4.3 2e-94 316.1 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 KFP19554.1 - 9.8e-06 25.0 0.0 0.00024 20.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.17 KFP19558.1 - 3.9e-105 350.8 0.0 6e-105 350.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP19558.1 - 7e-45 153.4 0.0 9.9e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KFP19558.1 - 8.1e-37 125.2 0.0 5.3e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP19558.1 - 6.9e-36 122.7 0.2 1.7e-12 47.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KFP19558.1 - 8.1e-27 93.4 0.1 5.5e-10 39.4 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KFP19558.1 - 2.7e-24 85.1 0.2 6.5e-08 32.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain FGFR3_TM PF18123.1 KFP19558.1 - 6.5e-15 54.4 7.1 1.1e-14 53.6 7.1 1.4 1 0 0 1 1 1 1 Fibroblast growth factor receptor 3 transmembrane domain V-set PF07686.17 KFP19558.1 - 1.7e-14 53.9 8.7 2.6e-05 24.3 0.1 5.5 4 3 1 5 5 5 3 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP19558.1 - 1.3e-08 35.1 0.0 0.61 10.5 0.0 4.1 3 1 0 3 3 3 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP19558.1 - 3.3e-08 33.7 0.0 0.0006 20.0 0.0 3.9 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP19558.1 - 4.1e-06 26.3 0.0 0.67 9.6 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP19558.1 - 0.00056 19.9 0.1 0.05 13.7 0.0 3.1 3 1 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KFP19558.1 - 0.0061 16.6 0.0 18 5.4 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain V-set_CD47 PF08204.11 KFP19558.1 - 0.033 14.1 1.0 0.96 9.4 0.0 3.1 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain INCENP_ARK-bind PF03941.15 KFP19558.1 - 0.047 13.6 0.2 0.19 11.7 0.6 1.7 2 0 0 2 2 1 0 Inner centromere protein, ARK binding region Shisa PF13908.6 KFP19558.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 KFP19558.1 - 0.081 12.9 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Pkinase_fungal PF17667.1 KFP19558.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LETM1 PF07766.13 KFP19559.1 - 1.8e-109 365.2 8.5 1.8e-109 365.2 8.5 3.9 2 1 0 4 4 4 1 LETM1-like protein EF-hand_6 PF13405.6 KFP19559.1 - 0.0027 17.5 0.2 1.1 9.3 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain Laminin_II PF06009.12 KFP19559.1 - 0.008 16.2 6.1 0.008 16.2 6.1 3.2 2 1 0 2 2 2 1 Laminin Domain II SAP PF02037.27 KFP19559.1 - 0.015 15.0 0.2 0.015 15.0 0.2 3.4 3 1 0 3 3 3 0 SAP domain EF-hand_1 PF00036.32 KFP19559.1 - 0.017 14.6 0.3 0.36 10.5 0.1 2.9 2 0 0 2 2 2 0 EF hand MinC_N PF05209.13 KFP19559.1 - 0.028 14.4 0.8 0.93 9.5 0.0 3.3 3 0 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain Acetyltransf_11 PF13720.6 KFP19559.1 - 0.42 11.1 3.9 0.48 10.9 0.4 3.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_7 PF13499.6 KFP19559.1 - 1.5 9.3 6.4 0.51 10.8 0.1 3.5 4 0 0 4 4 4 0 EF-hand domain pair YgaB PF14182.6 KFP19559.1 - 4.2 7.8 18.3 0.18 12.2 5.4 4.6 3 0 0 3 3 3 0 YgaB-like protein Neuropep_like PF15161.6 KFP19562.1 - 1.1e-29 101.9 0.2 1.4e-29 101.6 0.2 1.1 1 0 0 1 1 1 1 Neuropeptide-like DUF2909 PF11137.8 KFP19562.1 - 0.073 13.0 1.6 0.98 9.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) Acetyltransf_1 PF00583.25 KFP19564.1 - 2.2e-14 53.7 0.1 2.8e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFP19564.1 - 3.6e-13 49.7 0.0 5.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFP19564.1 - 1.6e-12 47.4 0.1 2.9e-12 46.7 0.1 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFP19564.1 - 2.7e-07 30.6 0.0 8.9e-06 25.8 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KFP19564.1 - 8.9e-05 23.2 0.1 0.00012 22.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KFP19564.1 - 0.00011 21.8 0.1 0.00072 19.1 0.1 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 KFP19564.1 - 0.0016 18.3 1.2 0.0042 17.0 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KFP19564.1 - 0.0028 17.7 0.2 0.031 14.4 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFP19564.1 - 0.0035 17.0 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP19564.1 - 0.0061 16.7 0.0 0.0081 16.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KFP19564.1 - 0.086 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DNA_pol_A PF00476.20 KFP19565.1 - 7.2e-121 403.8 5.8 9e-121 403.5 5.8 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 KFP19565.1 - 6.8e-88 293.6 3.5 3.5e-87 291.3 3.0 2.3 2 1 0 2 2 2 1 DNA polymerase nu pseudo-exo FOXP-CC PF16159.5 KFP19565.1 - 0.053 14.2 0.0 0.22 12.1 0.0 2.1 1 0 0 1 1 1 0 FOXP coiled-coil domain HAUS-augmin3 PF14932.6 KFP19566.1 - 8.6e-80 268.1 25.5 8.6e-80 268.1 25.5 4.1 3 1 0 4 4 4 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.12 KFP19566.1 - 0.0059 16.7 2.4 0.0059 16.7 2.4 4.7 4 1 0 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus WD40_alt PF14077.6 KFP19566.1 - 0.041 13.8 5.4 0.41 10.5 0.0 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif Pox_A3L PF05288.11 KFP19566.1 - 0.19 11.7 5.4 3.5 7.7 0.1 3.7 3 0 0 3 3 3 0 Poxvirus A3L Protein EzrA PF06160.12 KFP19566.1 - 2.2 6.3 57.0 0.23 9.6 9.8 4.2 3 1 1 4 4 4 0 Septation ring formation regulator, EzrA HLH PF00010.26 KFP19567.1 - 6.1e-12 45.3 3.0 4.4e-11 42.6 3.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.15 KFP19567.1 - 0.0023 18.0 8.0 0.0023 18.0 8.0 2.5 2 0 0 2 2 2 1 Myc leucine zipper domain Striatin PF08232.12 KFP19567.1 - 0.02 15.5 6.2 0.18 12.4 1.0 2.1 2 0 0 2 2 2 0 Striatin family UPF0449 PF15136.6 KFP19567.1 - 1.1 9.8 6.8 0.51 10.8 2.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Tugs PF17840.1 KFP19567.1 - 2.1 8.6 9.7 0.12 12.6 3.5 2.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain FYVE PF01363.21 KFP19568.1 - 3.6e-19 68.7 11.9 3.6e-19 68.7 11.9 3.0 3 1 0 3 3 3 1 FYVE zinc finger Cwf_Cwc_15 PF04889.12 KFP19568.1 - 3.4 7.3 11.8 11 5.6 11.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4668 PF15701.5 KFP19568.1 - 3.4 7.5 4.7 7.6 6.3 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Glyco_hydro_115 PF15979.5 KFP19570.1 - 0.035 13.6 4.6 0.093 12.2 4.6 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 UMPH-1 PF05822.12 KFP19570.1 - 4.4 6.7 9.1 6.8 6.1 7.4 2.0 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) zf-C3HC4_2 PF13923.6 KFP19571.1 - 3.8e-11 42.6 7.3 1.2e-10 41.0 7.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP19571.1 - 5.6e-11 42.6 6.2 1.1e-10 41.6 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP19571.1 - 1.5e-10 40.9 3.9 3.7e-10 39.7 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP19571.1 - 1.4e-09 37.6 5.8 2.7e-09 36.8 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP19571.1 - 4.7e-09 36.1 6.3 9e-09 35.2 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFP19571.1 - 1e-08 34.9 6.7 2.5e-08 33.6 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP19571.1 - 4.9e-07 29.5 11.1 7.8e-07 28.9 4.4 2.4 1 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFP19571.1 - 5e-06 26.2 3.3 1.3e-05 24.9 3.3 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFP19571.1 - 7.9e-05 22.9 8.0 0.00041 20.6 8.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KFP19571.1 - 0.00077 19.6 9.6 0.017 15.2 9.7 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFP19571.1 - 0.00077 19.5 4.3 0.0041 17.2 2.5 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 KFP19571.1 - 0.0063 16.1 3.8 0.012 15.2 3.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KFP19571.1 - 0.0081 15.9 1.9 0.023 14.5 1.9 1.8 1 1 0 1 1 1 1 RING-like zinc finger Rtf2 PF04641.12 KFP19571.1 - 0.015 14.7 6.8 0.022 14.1 5.4 2.1 1 1 0 1 1 1 0 Rtf2 RING-finger zf-P11 PF03854.14 KFP19571.1 - 0.026 14.2 2.4 0.026 14.2 2.4 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_10 PF16685.5 KFP19571.1 - 0.032 14.3 7.8 0.083 13.0 7.8 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 KFP19571.1 - 0.035 14.1 5.3 0.091 12.8 5.3 1.7 1 1 0 1 1 1 0 zinc-ribbons zf-RING_6 PF14835.6 KFP19571.1 - 0.081 12.8 6.0 0.32 10.9 6.0 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KFP19571.1 - 0.15 12.1 5.6 0.36 11.0 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) IBR PF01485.21 KFP19571.1 - 0.21 11.9 6.5 1 9.7 6.2 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-ANAPC11 PF12861.7 KFP19571.1 - 0.24 11.5 3.6 0.52 10.4 3.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFP19571.1 - 0.28 11.4 5.6 6.6 7.0 5.6 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.7 KFP19571.1 - 0.38 10.8 6.8 0.17 11.9 2.4 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 KFP19571.1 - 0.78 9.6 6.9 1.5 8.7 5.4 2.3 2 1 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 KFP19571.1 - 1 9.6 9.3 6.9 6.9 7.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 KFP19571.1 - 1.5 9.0 6.3 3.7 7.7 2.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 KFP19571.1 - 2.2 8.6 5.2 0.86 9.9 1.2 2.2 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase FAM193_C PF15914.5 KFP19574.1 - 5.6e-31 106.1 0.9 1.4e-30 104.8 0.9 1.8 1 0 0 1 1 1 1 FAM193 family C-terminal Sec34 PF04136.15 KFP19574.1 - 0.0027 17.6 1.5 0.0027 17.6 1.5 2.9 3 0 0 3 3 3 1 Sec34-like family Desmo_N PF06771.11 KFP19574.1 - 0.057 13.8 0.9 0.43 10.9 0.4 2.3 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus EABR PF12180.8 KFP19575.1 - 7e-16 57.6 4.5 7e-16 57.6 4.5 2.2 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 CC2-LZ PF16516.5 KFP19575.1 - 1.6e-08 34.8 12.1 1.6e-08 34.8 12.1 4.3 2 2 2 4 4 4 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FlxA PF14282.6 KFP19575.1 - 0.013 15.4 6.5 0.013 15.4 6.5 5.0 1 1 4 5 5 5 0 FlxA-like protein PRKG1_interact PF15898.5 KFP19575.1 - 0.18 12.7 0.4 0.18 12.7 0.4 4.9 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1192 PF06698.11 KFP19575.1 - 1.2 9.2 10.5 2.5 8.2 0.2 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF1192) Ribosomal_L12_N PF16320.5 KFP19575.1 - 1.8 8.4 3.4 6.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain ERM PF00769.19 KFP19575.1 - 2.7 7.7 42.5 0.42 10.4 25.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HU-CCDC81_bac_2 PF18175.1 KFP19575.1 - 7.5 6.5 8.8 1.4 8.9 0.4 3.6 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 PH PF00169.29 KFP19576.1 - 2.8e-19 69.6 0.2 5.1e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 KFP19576.1 - 5.3e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.6 KFP19576.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Aldolase_II PF00596.21 KFP19577.1 - 1.5e-44 152.2 0.1 2.3e-44 151.6 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 KFP19578.1 - 2.5e-35 122.0 47.1 8.9e-29 100.5 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP19578.1 - 7e-11 41.6 9.6 7e-11 41.6 9.6 2.3 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFP19578.1 - 7.9e-07 27.9 3.4 7.9e-07 27.9 3.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Nop14 PF04147.12 KFP19579.1 - 7.8e-262 871.4 42.0 8.8e-262 871.3 42.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2810 PF10928.8 KFP19579.1 - 0.0045 17.0 0.5 0.33 11.0 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2810) Mem_trans PF03547.18 KFP19579.1 - 0.17 10.2 0.0 0.39 9.1 0.0 1.5 1 0 0 1 1 1 0 Membrane transport protein PAP_central PF04928.17 KFP19579.1 - 3 6.8 5.6 3.8 6.4 3.9 2.0 2 0 0 2 2 2 0 Poly(A) polymerase central domain MFMR_assoc PF16596.5 KFP19579.1 - 3.3 8.2 9.8 8.3 6.9 9.8 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR Pkinase PF00069.25 KFP19580.1 - 1.5e-63 214.6 0.0 2e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19580.1 - 5.2e-34 117.7 0.0 7.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KFP19580.1 - 6.2e-22 78.1 0.1 1.5e-21 76.9 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 KFP19580.1 - 3.2e-05 23.4 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP19580.1 - 0.00024 20.0 0.0 0.00057 18.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase UDPG_MGDP_dh_C PF03720.15 KFP19580.1 - 0.092 13.2 0.0 0.39 11.1 0.0 2.1 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Myb_DNA-bind_4 PF13837.6 KFP19581.1 - 4.2e-12 46.3 1.5 4.2e-12 46.3 1.5 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFP19581.1 - 0.0045 17.3 0.2 0.0045 17.3 0.2 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF87 PF01935.17 KFP19581.1 - 0.58 10.2 4.3 1.2 9.2 2.1 2.0 1 1 1 2 2 2 0 Helicase HerA, central domain MCM_OB PF17207.3 KFP19581.1 - 0.84 9.5 4.4 4.4 7.2 0.1 2.5 2 1 0 2 2 2 0 MCM OB domain Myb_DNA-bind_3 PF12776.7 KFP19581.1 - 2.7 9.0 7.6 1.9 9.6 0.6 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RGS12_usC PF16612.5 KFP19583.1 - 4.8e-57 192.2 2.3 4.8e-57 192.2 2.3 3.5 3 1 1 4 4 4 1 C-terminal unstructured region of RGS12 RGS12_us1 PF16613.5 KFP19583.1 - 6.8e-57 190.9 15.1 6.8e-57 190.9 15.1 3.1 3 0 0 3 3 3 1 Unstructured region of RGS12 RBD PF02196.15 KFP19583.1 - 2.2e-31 107.7 0.0 1.5e-19 69.8 0.0 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.19 KFP19583.1 - 2.6e-28 98.7 3.6 4.9e-28 97.8 3.6 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS12_us2 PF16611.5 KFP19583.1 - 3e-28 98.0 9.8 3e-28 98.0 9.8 3.3 3 0 0 3 3 2 1 Unstructured region between RBD and GoLoco PDZ PF00595.24 KFP19583.1 - 8.7e-14 51.6 0.1 1.4e-12 47.8 0.0 3.0 2 1 1 3 3 3 1 PDZ domain GoLoco PF02188.17 KFP19583.1 - 4.4e-09 35.7 0.3 1.1e-08 34.5 0.3 1.7 1 0 0 1 1 1 1 GoLoco motif PDZ_6 PF17820.1 KFP19583.1 - 2.5e-08 33.7 0.0 6.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PID PF00640.23 KFP19583.1 - 0.00017 21.7 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) TUG-UBL1 PF11470.8 KFP19583.1 - 0.00061 20.0 0.2 0.23 11.7 0.0 4.2 5 0 0 5 5 5 1 TUG ubiquitin-like domain PDZ_2 PF13180.6 KFP19583.1 - 0.00082 19.7 0.0 0.0034 17.7 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PT-HINT PF07591.11 KFP19583.1 - 0.017 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Pretoxin HINT domain Trypsin PF00089.26 KFP19585.1 - 2.6e-74 249.8 0.6 3.6e-74 249.3 0.6 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP19585.1 - 2.3e-25 88.7 1.1 2.3e-25 88.7 1.1 2.6 3 0 0 3 3 3 1 Kringle domain fn2 PF00040.19 KFP19585.1 - 9.6e-15 54.6 15.5 2.9e-14 53.1 5.9 3.3 2 0 0 2 2 2 1 Fibronectin type II domain fn1 PF00039.18 KFP19585.1 - 3.2e-08 33.6 1.4 3.2e-08 33.6 1.4 3.6 3 0 0 3 3 3 1 Fibronectin type I domain EGF PF00008.27 KFP19585.1 - 1.8e-07 31.3 32.3 1.5e-06 28.3 10.3 4.0 4 0 0 4 4 4 2 EGF-like domain DUF1986 PF09342.11 KFP19585.1 - 3.4e-06 27.4 0.1 9.9e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.13 KFP19585.1 - 0.0029 17.9 33.5 0.018 15.4 10.1 4.1 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 KFP19585.1 - 0.039 14.6 5.0 0.039 14.6 5.0 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF IRS PF02174.17 KFP19586.1 - 1.3e-08 34.6 0.0 4e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 PTB domain (IRS-1 type) Alpha-2-MRAP_C PF06401.11 KFP19587.1 - 1.1e-72 244.4 29.5 1.1e-72 244.4 29.5 1.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.11 KFP19587.1 - 1.2e-26 93.0 29.5 1.7e-23 82.9 3.6 3.5 2 1 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Cellulase-like PF12876.7 KFP19587.1 - 0.023 14.0 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like Med30 PF11315.8 KFP19587.1 - 0.69 10.1 15.0 0.056 13.6 6.3 2.8 1 1 2 3 3 3 0 Mediator complex subunit 30 DUF5053 PF16476.5 KFP19587.1 - 1.2 8.9 5.2 5.2 6.8 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5053) 7tm_1 PF00001.21 KFP19588.1 - 2e-75 253.5 5.6 2.7e-75 253.1 5.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19588.1 - 1.1e-10 41.4 15.7 5.6e-08 32.5 5.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP19588.1 - 2.6e-07 30.7 9.3 1.7e-06 28.0 2.6 2.4 3 0 0 3 3 3 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP19588.1 - 1.1e-06 28.5 7.8 1.1e-06 28.5 7.8 2.6 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx FA_desaturase PF00487.24 KFP19588.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.5 2 2 1 3 3 3 0 Fatty acid desaturase DUF4614 PF15391.6 KFP19588.1 - 0.25 11.3 8.4 0.43 10.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Peptidase_M14 PF00246.24 KFP19589.1 - 5.7e-76 256.1 0.0 7.3e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.22 KFP19589.1 - 3.9e-21 75.7 2.5 8.5e-21 74.7 2.5 1.6 1 0 0 1 1 1 1 Fz domain CarboxypepD_reg PF13620.6 KFP19589.1 - 2.7e-15 56.4 0.0 5.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFP19589.1 - 1.5e-06 28.1 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Glypican PF01153.19 KFP19589.1 - 0.0099 14.8 1.4 0.014 14.2 1.4 1.1 1 0 0 1 1 1 1 Glypican AstE_AspA PF04952.14 KFP19589.1 - 0.022 13.9 0.0 1.6 7.7 0.1 2.8 3 1 0 3 3 3 0 Succinylglutamate desuccinylase / Aspartoacylase family 7tm_1 PF00001.21 KFP19590.1 - 1e-35 123.4 19.5 1.3e-35 123.1 19.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP19590.1 - 0.00072 19.3 23.6 0.0014 18.3 22.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.8 KFP19590.1 - 0.38 10.5 13.8 0.47 10.2 12.4 1.8 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 PGG PF13962.6 KFP19590.1 - 5.5 6.8 10.7 0.12 12.2 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function AdoMet_MTase PF07757.13 KFP19592.1 - 1.3e-40 138.2 0.1 2.7e-40 137.2 0.1 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KFP19592.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KFP19592.1 - 0.062 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFP19592.1 - 0.086 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFP19592.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ACOX PF01756.19 KFP19593.1 - 1.6e-50 171.2 0.0 2.6e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KFP19593.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFP19593.1 - 1.4e-08 35.1 0.1 1.1e-06 28.9 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KFP19593.1 - 7.5e-07 29.7 0.0 1.7e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Trypsin_2 PF13365.6 KFP19594.1 - 3.4e-29 102.7 0.1 4.9e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KFP19594.1 - 4.6e-15 56.0 0.0 6.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KFP19594.1 - 2.3e-13 49.7 0.0 3.3e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP19594.1 - 3.9e-11 43.1 0.2 2e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFP19594.1 - 1.9e-09 37.8 0.2 6.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 KFP19594.1 - 4.7e-05 22.2 1.7 0.05 12.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 KFP19594.1 - 0.00095 18.4 0.1 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.6 KFP19594.1 - 0.0012 18.7 0.1 0.0043 17.0 0.0 1.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF31 PF01732.16 KFP19594.1 - 0.038 13.5 0.4 5.6 6.4 0.1 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) TPR_12 PF13424.6 KFP19596.1 - 1.9e-15 56.9 38.1 2.5e-05 24.5 3.3 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP19596.1 - 2.1e-07 30.6 44.9 0.036 14.3 0.9 11.7 12 1 1 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19596.1 - 3.4e-06 26.7 42.8 0.16 12.2 0.5 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19596.1 - 0.00012 21.7 34.6 0.062 13.1 0.9 10.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFP19596.1 - 0.00063 19.5 16.8 0.011 15.6 1.1 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat SH3_1 PF00018.28 KFP19596.1 - 0.004 16.7 0.4 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 SH3 domain TPR_16 PF13432.6 KFP19596.1 - 0.051 14.2 20.1 0.14 12.8 0.6 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19596.1 - 0.071 13.2 23.2 1.2 9.4 0.4 8.6 10 1 0 10 10 10 0 Tetratricopeptide repeat Csd3_N PF18059.1 KFP19596.1 - 0.15 12.6 0.7 0.41 11.2 0.1 2.1 2 0 0 2 2 2 0 Csd3 N-terminal AbLIM_anchor PF16182.5 KFP19597.1 - 1.7e-118 396.8 31.1 1.2e-76 259.0 24.9 2.4 1 1 1 2 2 2 2 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFP19597.1 - 3.7e-41 139.1 42.7 4.3e-14 52.5 2.9 4.3 4 0 0 4 4 4 4 LIM domain VHP PF02209.19 KFP19597.1 - 5.8e-16 58.3 2.5 1.2e-15 57.3 2.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.29 KFP19599.1 - 2.9e-26 92.0 1.4 1.3e-12 48.1 0.9 2.7 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KFP19599.1 - 0.00021 21.6 2.5 1.6 9.1 0.6 4.3 3 2 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 KFP19599.1 - 0.00026 21.4 7.0 0.026 14.9 0.0 4.2 4 1 0 4 4 4 2 Pleckstrin homology domain Sharpin_PH PF16764.5 KFP19599.1 - 0.0035 17.1 0.2 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Sharpin PH domain ERM PF00769.19 KFP19599.1 - 0.0074 16.1 8.2 0.0074 16.1 8.2 2.0 3 0 0 3 3 3 1 Ezrin/radixin/moesin family Spc7 PF08317.11 KFP19599.1 - 0.13 11.1 15.5 0.27 10.1 15.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup188_C PF18378.1 KFP19599.1 - 0.77 8.5 3.9 1.2 7.8 3.9 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Prefoldin_2 PF01920.20 KFP19599.1 - 0.97 9.4 18.2 0.51 10.3 4.7 3.1 3 0 0 3 3 3 0 Prefoldin subunit Sortilin-Vps10 PF15902.5 KFP19600.1 - 4.9e-94 315.6 0.6 7.6e-94 315.0 0.6 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFP19600.1 - 8.5e-37 127.1 2.5 1.3e-36 126.5 2.5 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFP19600.1 - 1e-07 31.7 0.0 1.7e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 PKD domain BNR PF02012.20 KFP19600.1 - 0.01 15.7 10.7 2.4 8.5 0.3 5.2 5 0 0 5 5 5 0 BNR/Asp-box repeat GrpE PF01025.19 KFP19603.1 - 1.3e-45 155.1 4.1 1.5e-45 154.8 4.1 1.1 1 0 0 1 1 1 1 GrpE Laminin_I PF06008.14 KFP19603.1 - 0.0096 15.7 8.7 0.012 15.4 8.7 1.1 1 0 0 1 1 1 1 Laminin Domain I Cpn60_TCP1 PF00118.24 KFP19603.1 - 0.012 14.2 2.5 0.014 14.0 2.5 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family LOH1CR12 PF10158.9 KFP19603.1 - 0.034 14.2 1.5 0.047 13.7 1.5 1.3 1 0 0 1 1 1 0 Tumour suppressor protein MetJ PF01340.20 KFP19603.1 - 0.036 14.1 0.7 0.14 12.2 0.1 2.0 1 1 1 2 2 2 0 Met Apo-repressor, MetJ DUF2205 PF10224.9 KFP19603.1 - 0.19 11.7 6.7 0.11 12.5 4.0 1.9 1 1 1 2 2 2 0 Short coiled-coil protein DUF3391 PF11871.8 KFP19603.1 - 0.28 11.7 6.0 0.56 10.7 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1993 PF09351.10 KFP19603.1 - 0.4 10.8 3.2 10 6.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) TERB2 PF15101.6 KFP19603.1 - 0.47 10.5 3.4 0.62 10.1 3.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3347 PF11827.8 KFP19603.1 - 0.47 10.6 7.1 0.6 10.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) CRR7 PF12095.8 KFP19603.1 - 0.51 10.8 5.5 0.22 12.0 2.4 1.9 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Connexin PF00029.19 KFP19603.1 - 0.58 9.9 2.1 0.78 9.5 2.1 1.1 1 0 0 1 1 1 0 Connexin DUF5320 PF17253.2 KFP19603.1 - 7.9 7.6 5.6 2.8 9.0 2.9 1.7 2 0 0 2 2 1 0 Family of unknown function (DUF5320) SWIRM PF04433.17 KFP19604.1 - 0.04 14.3 0.6 0.12 12.7 0.0 2.1 2 1 0 2 2 2 0 SWIRM domain Pertussis_S1 PF02917.14 KFP19604.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 RabGAP-TBC PF00566.18 KFP19605.1 - 1.8e-49 168.3 0.0 4.3e-49 167.1 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ARGLU PF15346.6 KFP19605.1 - 7.3 6.5 14.7 1.8 8.4 7.4 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF4603 PF15376.6 KFP19607.1 - 0 2180.5 48.1 0 2180.3 48.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) 7tm_1 PF00001.21 KFP19609.1 - 2e-46 158.5 23.4 3.7e-46 157.6 23.4 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19609.1 - 4.5e-08 32.8 25.8 6.1e-08 32.4 25.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP19609.1 - 0.0024 17.5 22.9 0.0024 17.5 22.9 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx LCAT PF02450.15 KFP19610.1 - 1.3e-86 291.3 0.7 1.8e-84 284.2 0.7 2.2 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KFP19610.1 - 3.2e-05 23.4 0.6 0.05 12.9 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KFP19610.1 - 0.0018 18.9 0.0 0.0023 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFP19610.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFP19610.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KFP19610.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Exo_endo_phos PF03372.23 KFP19613.1 - 7.6e-06 25.6 0.0 9.1e-05 22.1 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM_6 PF03422.15 KFP19613.1 - 0.029 14.7 0.1 0.088 13.1 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) PrmA PF06325.13 KFP19614.1 - 3.9e-06 26.5 0.0 2.3e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KFP19614.1 - 0.00026 20.5 0.3 0.081 12.4 0.1 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 KFP19614.1 - 0.0009 19.9 0.0 0.0023 18.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFP19614.1 - 0.0017 18.3 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP19614.1 - 0.035 13.8 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KFP19614.1 - 0.051 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFP19614.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Iwr1 PF08574.10 KFP19615.1 - 4.7e-07 30.7 19.2 4.7e-07 30.7 19.2 2.9 3 2 0 3 3 3 1 Transcription factor Iwr1 AA_permease_2 PF13520.6 KFP19616.1 - 2.8e-63 214.2 40.9 3.5e-63 213.9 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFP19616.1 - 2.9e-23 82.2 33.6 3.6e-23 81.9 33.1 1.3 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KFP19617.1 - 5.3e-26 91.5 0.0 6.3e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19617.1 - 9.2e-25 87.4 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ArgoL1 PF08699.10 KFP19617.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Argonaute linker 1 domain Pyr_redox_3 PF13738.6 KFP19618.1 - 8.7e-13 48.2 0.0 1.3e-08 34.5 0.0 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP19618.1 - 8.4e-09 35.1 0.0 1.8e-07 30.7 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP19618.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) EF-hand_1 PF00036.32 KFP19619.1 - 1.2e-05 24.5 2.0 0.02 14.4 0.2 2.9 1 1 2 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP19619.1 - 2e-05 24.2 1.2 0.028 14.4 0.3 2.6 1 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KFP19619.1 - 0.00013 21.7 1.5 0.00032 20.5 1.5 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP19619.1 - 0.0015 19.0 1.6 0.0077 16.7 1.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP19619.1 - 0.007 15.8 1.8 0.37 10.4 0.1 2.7 2 1 0 2 2 2 1 EF hand HAUS-augmin3 PF14932.6 KFP19619.1 - 0.044 13.3 0.5 0.06 12.9 0.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SMC_Nse1 PF07574.13 KFP19619.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Peptidase_S8 PF00082.22 KFP19620.1 - 8.2e-40 136.9 0.1 1.3e-39 136.2 0.1 1.3 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 KFP19620.1 - 0.057 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system adh_short PF00106.25 KFP19621.1 - 2.2e-41 141.5 0.1 2.8e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP19621.1 - 5.3e-26 91.6 0.0 7.2e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP19621.1 - 2.3e-07 30.9 0.0 3.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFP19621.1 - 0.00021 20.5 0.3 0.00072 18.8 0.3 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFP19621.1 - 0.0029 17.1 0.6 0.046 13.2 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFP19621.1 - 0.005 17.1 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KFP19621.1 - 0.036 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Peptidase_S32 PF05579.13 KFP19621.1 - 0.039 13.2 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 ApbA PF02558.16 KFP19621.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRR_9 PF14580.6 KFP19622.1 - 9.3e-17 61.1 6.5 2.6e-14 53.1 4.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFP19622.1 - 1.1e-15 57.4 27.3 8.4e-06 26.0 3.3 4.1 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP19622.1 - 1e-10 41.2 21.9 1.3e-06 28.0 8.3 4.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KFP19622.1 - 0.0005 19.9 18.0 0.063 13.4 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich repeat Arm_3 PF16186.5 KFP19622.1 - 1.6 8.4 6.8 3.2 7.4 0.1 3.8 3 1 2 5 5 5 0 Atypical Arm repeat LRR_1 PF00560.33 KFP19622.1 - 5.4 8.0 19.5 28 5.8 2.9 5.7 5 1 1 6 6 6 0 Leucine Rich Repeat HSF_DNA-bind PF00447.17 KFP19623.1 - 1.1e-31 109.3 0.5 1.1e-31 109.3 0.5 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Vert_HS_TF PF06546.11 KFP19623.1 - 1.2e-19 71.0 0.1 1.2e-19 71.0 0.1 1.7 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor YscO PF07321.12 KFP19623.1 - 0.0038 17.2 5.1 0.0057 16.6 5.1 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO MobL PF18555.1 KFP19623.1 - 0.0078 15.5 0.7 0.011 15.0 0.7 1.1 1 0 0 1 1 1 1 MobL relaxases Ets PF00178.22 KFP19623.1 - 0.093 13.2 1.1 0.76 10.3 0.0 2.8 3 0 0 3 3 3 0 Ets-domain Glyco_transf_41 PF13844.6 KFP19623.1 - 0.22 9.9 0.9 0.29 9.5 0.9 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 ZapB PF06005.12 KFP19623.1 - 0.51 10.8 9.5 0.6 10.6 8.5 1.6 1 1 0 1 1 1 0 Cell division protein ZapB TRADD_N PF09034.10 KFP19624.1 - 7.9e-48 161.2 3.0 1.3e-47 160.5 3.0 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain Death PF00531.22 KFP19624.1 - 3.2e-09 36.8 0.4 1.3e-08 34.9 0.3 2.0 2 0 0 2 2 2 1 Death domain UPF0183 PF03676.14 KFP19625.1 - 7.9e-158 525.8 0.3 8.8e-158 525.7 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.17 KFP19626.1 - 1.6e-48 164.5 0.1 1.8e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit DUF1674 PF07896.12 KFP19626.1 - 2.8 8.5 6.5 21 5.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) G-alpha PF00503.20 KFP19627.1 - 2.8e-108 362.3 3.0 3.2e-108 362.1 3.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP19627.1 - 3.6e-13 49.4 0.0 8.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP19627.1 - 0.00057 19.3 0.5 0.00087 18.7 0.5 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region HMG_CoA_synt_C PF08540.10 KFP19627.1 - 0.034 13.8 0.4 0.52 9.9 0.0 2.4 2 1 1 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal G2BR PF18442.1 KFP19628.1 - 1.1e-17 63.4 7.9 3.4e-17 61.8 7.9 2.0 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) zf-RING_2 PF13639.6 KFP19628.1 - 3e-12 46.7 7.1 3e-12 46.7 7.1 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP19628.1 - 3.5e-10 39.5 6.3 9.2e-10 38.2 6.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CUE PF02845.16 KFP19628.1 - 4e-10 39.2 0.1 8.3e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4 PF00097.25 KFP19628.1 - 4.8e-08 32.7 5.2 8.8e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP19628.1 - 1.1e-07 31.6 3.2 2.5e-07 30.5 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP19628.1 - 1.9e-07 31.0 2.4 4.1e-07 29.9 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFP19628.1 - 6.2e-07 29.0 1.5 6.2e-07 29.0 1.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KFP19628.1 - 6.6e-07 29.5 9.6 6.5e-06 26.4 8.7 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP19628.1 - 1.7e-05 24.6 3.6 3.3e-05 23.8 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP19628.1 - 1.8e-05 24.5 5.4 3.7e-05 23.5 5.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP19628.1 - 2.8e-05 24.1 0.6 8.8e-05 22.5 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP19628.1 - 3e-05 23.5 4.4 7.3e-05 22.3 4.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KFP19628.1 - 0.0028 17.8 4.6 0.0053 16.9 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Form-deh_trans PF09163.11 KFP19628.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane RINGv PF12906.7 KFP19628.1 - 0.28 11.4 7.6 0.6 10.3 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KFP19628.1 - 0.47 10.7 5.6 1.4 9.1 5.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain NUDIX_2 PF13869.6 KFP19629.1 - 1.2e-69 233.7 0.0 1.6e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 KFP19629.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 NUDIX domain Ofd1_CTDD PF10637.9 KFP19630.1 - 9.6e-43 146.4 0.0 2.5e-37 128.6 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFP19630.1 - 2.2e-33 114.8 0.1 1.2e-29 102.8 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFP19630.1 - 1.4e-13 51.5 0.0 1.2e-12 48.5 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BBS2_C PF14782.6 KFP19631.1 - 7e-196 651.1 0.0 1e-194 647.3 0.0 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KFP19631.1 - 3.2e-46 155.8 0.0 4.2e-44 149.0 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 KFP19631.1 - 6.8e-27 93.4 0.0 2.4e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.23 KFP19631.1 - 2.5e-06 27.5 0.2 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 KFP19631.1 - 2.6e-05 24.7 1.6 0.022 15.3 0.4 3.4 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 KFP19631.1 - 0.00024 20.2 0.3 0.23 10.5 0.0 3.1 2 1 1 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 Metallothio PF00131.20 KFP19632.1 - 2.6e-21 75.5 63.7 2.9e-21 75.4 63.7 1.0 1 0 0 1 1 1 1 Metallothionein Nic96 PF04097.14 KFP19633.1 - 1.8e-195 651.0 0.1 2.8e-195 650.4 0.1 1.3 1 0 0 1 1 1 1 Nup93/Nic96 Nup84_Nup100 PF04121.13 KFP19633.1 - 0.00043 18.5 0.3 0.00082 17.6 0.3 1.4 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 AA_permease PF00324.21 KFP19634.1 - 3.6e-134 448.0 36.0 4.6e-134 447.6 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFP19634.1 - 2.3e-108 363.0 0.0 1.4e-55 189.1 0.0 2.5 1 1 1 2 2 2 2 Solute carrier family 12 Tmemb_170 PF10190.9 KFP19635.1 - 2.5e-38 130.7 8.8 2.8e-38 130.5 8.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Chromate_transp PF02417.15 KFP19635.1 - 0.094 12.9 8.2 0.1 12.7 8.2 1.1 1 0 0 1 1 1 0 Chromate transporter DUF4235 PF14019.6 KFP19635.1 - 0.16 12.0 3.2 0.83 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) DUF5489 PF17592.2 KFP19635.1 - 0.22 12.0 4.8 0.33 11.5 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5489) BCNT PF07572.12 KFP19636.1 - 4.7e-30 103.5 0.3 4.7e-30 103.5 0.3 3.1 4 0 0 4 4 4 1 Bucentaur or craniofacial development WD40 PF00400.32 KFP19637.1 - 6.1e-13 49.0 21.9 2.9e-05 24.8 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KFP19637.1 - 2.5e-11 43.0 15.5 2.5e-11 43.0 15.5 2.3 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 KFP19637.1 - 3.5e-07 30.5 7.0 3.5e-07 30.5 7.0 2.4 1 1 1 2 2 2 1 Zinc-ribbon like family eIF2A PF08662.11 KFP19637.1 - 0.00092 19.1 0.9 0.048 13.5 0.2 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFP19637.1 - 0.029 14.6 0.7 4 7.8 0.0 3.5 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 KFP19637.1 - 0.096 13.0 10.7 0.35 11.2 10.7 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFP19637.1 - 0.49 10.8 14.6 0.031 14.6 5.5 3.1 2 0 0 2 2 2 0 Ring finger domain FA_hydroxylase PF04116.13 KFP19638.1 - 3.9e-16 59.6 11.0 3.9e-16 59.6 11.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM189_B_dmain PF10520.9 KFP19638.1 - 0.094 12.8 7.3 0.53 10.4 1.2 2.3 2 0 0 2 2 2 0 B domain of TMEM189, localisation domain Anth_synt_I_N PF04715.13 KFP19638.1 - 0.1 12.8 2.4 0.3 11.3 2.4 1.8 1 1 1 2 2 2 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KFP19638.1 - 0.21 11.5 8.3 0.081 12.8 3.5 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Pkinase_Tyr PF07714.17 KFP19639.1 - 9.2e-45 152.9 0.3 6.9e-42 143.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KFP19639.1 - 8e-29 100.8 0.1 3.2e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain RPW8 PF05659.11 KFP19639.1 - 0.049 13.3 6.4 0.03 14.0 2.7 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-RING_2 PF13639.6 KFP19640.1 - 1.3e-08 35.1 2.2 1.3e-08 35.1 2.2 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KFP19640.1 - 2.4e-08 33.7 0.8 2.4e-08 33.7 0.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP19640.1 - 1e-06 28.7 0.7 4.4e-06 26.6 0.7 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP19640.1 - 2.2e-06 27.4 0.8 2.2e-06 27.4 0.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP19640.1 - 4.6e-06 26.4 1.9 4.6e-06 26.4 1.9 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP19640.1 - 0.00011 22.5 4.5 0.00011 22.5 4.5 2.9 3 1 0 3 3 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KFP19640.1 - 0.00014 21.5 0.4 0.00086 19.0 0.4 2.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFP19640.1 - 0.00043 20.2 2.1 0.00043 20.2 2.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP19640.1 - 0.0021 17.9 0.8 0.012 15.5 0.8 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP19640.1 - 0.003 17.7 0.6 0.003 17.7 0.6 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 KFP19640.1 - 0.0032 16.9 1.7 0.0063 15.9 1.7 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 KFP19640.1 - 0.0056 16.7 0.8 0.031 14.3 0.8 2.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Casc1_N PF15927.5 KFP19640.1 - 0.044 13.5 2.3 0.08 12.6 2.3 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Zn_ribbon_17 PF17120.5 KFP19640.1 - 0.08 12.6 2.8 0.39 10.4 1.9 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF4407 PF14362.6 KFP19640.1 - 0.51 9.6 2.2 0.82 9.0 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 KFP19640.1 - 0.56 9.0 12.6 0.0087 15.0 5.3 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FAD-SLDH PF12318.8 KFP19640.1 - 1.6 8.8 3.6 1.4 8.9 1.4 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DDE_Tnp_1_6 PF13751.6 KFP19640.1 - 3.2 8.0 6.3 0.48 10.7 2.3 1.6 2 0 0 2 2 1 0 Transposase DDE domain zf-RING_4 PF14570.6 KFP19640.1 - 6.3 6.7 11.5 0.054 13.3 2.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cys_rich_FGFR PF00839.17 KFP19641.1 - 7.8e-203 656.9 115.7 2.1e-17 63.0 1.8 15.2 15 0 0 15 15 15 15 Cysteine rich repeat IFT43 PF15305.6 KFP19641.1 - 0.042 14.0 0.3 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF445 PF04286.12 KFP19641.1 - 5.6 6.7 8.8 6.8 6.4 6.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) GCV_T PF01571.21 KFP19642.1 - 2.5e-67 226.9 0.0 4.4e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KFP19642.1 - 1.3e-57 196.0 0.0 1.9e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 KFP19642.1 - 8e-15 54.9 0.2 2.3e-14 53.5 0.0 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KFP19642.1 - 1.4e-13 50.6 0.0 3.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 KFP19642.1 - 3.5e-06 26.5 0.0 0.023 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP19642.1 - 3.7e-06 26.3 1.6 1.1e-05 24.7 1.6 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFP19642.1 - 9.8e-06 25.0 0.4 0.06 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KFP19642.1 - 3.6e-05 23.3 0.4 0.036 13.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.14 KFP19642.1 - 0.00022 20.2 1.0 0.027 13.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KFP19642.1 - 0.004 16.4 3.0 0.035 13.4 3.1 2.3 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFP19642.1 - 0.01 14.6 0.8 0.02 13.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KFP19642.1 - 0.011 14.9 0.6 0.27 10.5 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KFP19642.1 - 0.017 15.7 1.7 5.7 7.6 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFP19642.1 - 0.018 15.3 0.2 0.063 13.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFP19642.1 - 0.019 14.3 2.4 0.038 13.3 2.4 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KFP19642.1 - 0.097 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KFP19642.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_29 PF00777.18 KFP19643.1 - 1.1e-61 208.6 0.0 1.3e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Fucokinase PF07959.12 KFP19644.1 - 1.3e-100 337.2 0.0 1.6e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 KFP19644.1 - 3.8e-07 30.4 0.0 9.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KFP19644.1 - 3.2e-05 24.1 4.8 3.8e-05 23.8 0.3 2.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain COG4 PF08318.12 KFP19645.1 - 3.5e-102 341.9 7.8 7.2e-102 340.9 7.8 1.6 1 0 0 1 1 1 1 COG4 transport protein Bac_thur_toxin PF01338.18 KFP19645.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacillus thuringiensis toxin GCP_C_terminal PF04130.13 KFP19645.1 - 0.07 12.6 4.4 0.32 10.4 3.3 2.5 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal MMS1_N PF10433.9 KFP19646.1 - 3.2e-176 586.8 0.0 1.2e-175 584.9 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFP19646.1 - 1.4e-95 320.3 0.0 2.6e-94 316.2 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region IL34 PF15036.6 KFP19647.1 - 3.3e-42 144.2 3.4 3.6e-42 144.1 3.4 1.0 1 0 0 1 1 1 1 Interleukin 34 IMD PF08397.11 KFP19648.1 - 1.3e-101 338.5 2.4 1.9e-101 338.0 2.4 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain YlqD PF11068.8 KFP19648.1 - 3.2 8.2 5.9 6.2 7.2 5.9 1.4 1 0 0 1 1 1 0 YlqD protein Vac14_Fig4_bd PF11916.8 KFP19649.1 - 2.6e-79 265.0 9.7 4.6e-79 264.2 9.7 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KFP19649.1 - 1.4e-45 153.8 0.1 4.4e-40 136.2 0.0 4.3 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFP19649.1 - 5.8e-08 32.3 0.4 0.017 15.4 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 KFP19649.1 - 2.3e-06 28.0 0.1 0.31 11.6 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KFP19649.1 - 0.0012 18.9 2.3 0.89 9.6 0.1 3.8 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP19649.1 - 0.0036 17.7 0.0 47 4.5 0.0 4.1 3 2 0 3 3 3 0 HEAT repeats FtsJ PF01728.19 KFP19650.1 - 1.2e-28 100.4 0.0 1.6e-27 96.7 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase PNP_UDP_1 PF01048.20 KFP19651.1 - 4.3e-49 166.9 0.1 4.8e-49 166.7 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily EF-hand_6 PF13405.6 KFP19652.1 - 1.7e-07 30.6 0.1 0.00019 21.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP19652.1 - 2.8e-07 29.6 0.5 0.0002 20.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP19652.1 - 2e-06 28.1 0.2 3.3e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP19652.1 - 0.00012 21.4 2.3 0.00075 18.9 0.0 2.7 3 0 0 3 3 3 1 EF hand Aminotran_1_2 PF00155.21 KFP19653.1 - 5.6e-91 305.4 0.0 6.3e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.18 KFP19654.1 - 5e-55 186.9 23.9 6.2e-55 186.5 23.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFP19654.1 - 4.8e-08 32.5 22.0 1.1e-07 31.3 15.8 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Spore_permease PF03845.13 KFP19654.1 - 0.0025 16.7 5.3 0.0025 16.7 5.3 2.5 3 0 0 3 3 3 2 Spore germination protein COXG PF06240.13 KFP19654.1 - 0.15 11.8 0.2 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) Rubis-subs-bind PF09273.11 KFP19655.1 - 6.5e-17 62.4 5.6 1.3e-16 61.5 5.6 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KFP19655.1 - 7.4e-15 55.7 0.1 7.5e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 SET domain RNA_pol_Rpo13 PF12136.8 KFP19655.1 - 0.094 12.6 5.5 0.11 12.5 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Agouti PF05039.12 KFP19656.1 - 3e-30 104.8 4.2 4e-30 104.4 4.2 1.2 1 0 0 1 1 1 1 Agouti protein vATP-synt_AC39 PF01992.16 KFP19657.1 - 1.5e-115 386.3 0.2 1.7e-115 386.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nab2p_Zf1 PF18260.1 KFP19657.1 - 0.066 13.1 0.6 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 adh_short PF00106.25 KFP19658.1 - 4.1e-41 140.6 0.0 6e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP19658.1 - 1.5e-25 90.1 0.0 2.3e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFP19658.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Na_H_Exchanger PF00999.21 KFP19659.1 - 1.3e-84 284.2 38.7 1.6e-84 283.9 38.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 KFP19659.1 - 2.4e-05 24.5 3.6 6.2e-05 23.2 3.6 1.6 1 0 0 1 1 1 1 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin PIG-H PF10181.9 KFP19659.1 - 0.99 9.3 5.8 0.097 12.5 0.6 2.0 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component BTB_2 PF02214.22 KFP19660.1 - 1.2e-14 54.4 1.0 3.1e-05 24.2 0.0 3.8 4 0 0 4 4 4 3 BTB/POZ domain TAFH PF07531.14 KFP19660.1 - 0.0073 16.4 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 NHR1 homology to TAF Atypical_Card PF18461.1 KFP19660.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Atypical caspase recruitment domain p25-alpha PF05517.12 KFP19661.1 - 8.9e-66 220.8 8.5 1e-65 220.7 8.5 1.0 1 0 0 1 1 1 1 p25-alpha DnaB PF00772.21 KFP19661.1 - 0.0091 16.1 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase N terminal domain DHHC PF01529.20 KFP19662.1 - 3.2e-33 114.7 11.0 3.2e-33 114.7 11.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.6 KFP19662.1 - 2.9 7.5 9.6 0.82 9.3 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Virul_fac_BrkB PF03631.15 KFP19662.1 - 7.5 6.1 14.2 0.66 9.5 0.6 2.6 2 1 1 3 3 3 0 Virulence factor BrkB Lectin_C PF00059.21 KFP19663.1 - 3e-16 60.1 0.3 4.4e-16 59.5 0.3 1.3 1 0 0 1 1 1 1 Lectin C-type domain EGF PF00008.27 KFP19663.1 - 1.8 9.0 30.4 0.09 13.1 6.6 3.9 4 0 0 4 4 4 0 EGF-like domain tRNA-synt_2c PF01411.19 KFP19664.1 - 7.7e-227 754.2 0.0 1.1e-226 753.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFP19664.1 - 8.1e-17 61.1 0.1 1.9e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFP19664.1 - 9.2e-17 61.7 0.5 9.2e-17 61.7 0.5 2.0 2 0 0 2 2 2 1 DHHA1 domain Syntaxin-6_N PF09177.11 KFP19664.1 - 0.018 15.6 1.7 0.05 14.1 1.7 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Lipase_GDSL_3 PF14606.6 KFP19664.1 - 0.04 14.1 0.1 0.084 13.0 0.1 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Spc7 PF08317.11 KFP19664.1 - 0.11 11.3 3.4 0.23 10.3 3.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 KFP19664.1 - 2.2 8.5 4.4 1.9 8.6 0.3 2.8 3 0 0 3 3 3 0 bZIP transcription factor DUF4404 PF14357.6 KFP19664.1 - 2.7 8.7 6.8 2.7 8.7 2.7 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) CARMIL_C PF16000.5 KFP19667.1 - 4.6e-47 161.1 10.5 3.2e-30 105.8 0.5 3.2 3 0 0 3 3 3 2 CARMIL C-terminus LRR_6 PF13516.6 KFP19667.1 - 7.4e-11 41.2 17.8 0.00017 21.4 0.1 8.2 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 KFP19667.1 - 0.0063 16.9 10.1 1.3 9.9 0.4 6.9 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 KFP19667.1 - 0.012 16.0 14.6 0.29 11.6 0.3 6.8 4 2 4 8 8 8 0 Leucine Rich repeats (2 copies) zf-H2C2_2 PF13465.6 KFP19668.1 - 1.2e-50 167.8 95.0 1e-08 35.2 0.6 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.26 KFP19668.1 - 8e-34 114.2 102.2 8.8e-05 22.7 1.1 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP19668.1 - 5.3e-26 89.1 96.8 0.0048 17.6 2.7 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP19668.1 - 1.6e-16 59.7 87.6 1.1e-06 28.3 0.6 10.6 11 0 0 11 11 11 5 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KFP19668.1 - 8.6e-10 38.6 58.3 0.042 14.1 0.1 11.1 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP19668.1 - 0.0061 16.9 1.3 0.0061 16.9 1.3 9.7 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP19668.1 - 0.021 14.8 1.6 0.021 14.8 1.6 11.0 11 2 0 11 11 10 0 C2H2-type zinc finger C1_1 PF00130.22 KFP19668.1 - 0.5 10.3 43.8 0.34 10.8 0.9 7.7 3 2 6 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KFP19668.1 - 1.3 8.6 0.0 1.3 8.6 0.0 6.9 8 1 0 8 8 8 0 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 KFP19668.1 - 1.7 8.5 31.0 3.6 7.5 0.1 7.9 1 1 9 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.7 KFP19668.1 - 2.9 8.3 61.6 2.4 8.6 7.0 7.5 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KFP19668.1 - 6.8 7.5 43.9 5.4 7.8 0.9 5.9 2 1 4 6 6 6 0 zinc-ribbon family adh_short PF00106.25 KFP19669.1 - 1.2e-23 83.6 0.0 2.4e-23 82.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP19669.1 - 1.4e-21 77.1 0.0 2.2e-21 76.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1704 PF08014.11 KFP19670.1 - 1.5e-12 47.3 0.1 2.9e-12 46.3 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) DUF3361 PF11841.8 KFP19671.1 - 7.9e-57 191.5 5.0 7.9e-57 191.5 5.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KFP19671.1 - 4.5e-43 147.4 0.7 7.4e-43 146.7 0.7 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KFP19671.1 - 1.8e-11 44.7 0.0 4.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Arm_2 PF04826.13 KFP19671.1 - 0.011 15.2 4.4 0.19 11.2 1.9 2.3 2 0 0 2 2 2 0 Armadillo-like DegT_DnrJ_EryC1 PF01041.17 KFP19671.1 - 0.043 13.1 0.8 0.065 12.5 0.8 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family E2F_CC-MB PF16421.5 KFP19672.1 - 1.1e-24 86.6 0.0 1.8e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KFP19672.1 - 1.9e-14 53.4 0.2 4.6e-14 52.2 0.2 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DivIC PF04977.15 KFP19672.1 - 0.08 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Sec6 PF06046.13 KFP19673.1 - 3.4e-117 392.2 0.4 5.2e-117 391.6 0.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF1242 PF06842.12 KFP19673.1 - 0.086 12.7 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) Pkinase PF00069.25 KFP19674.1 - 1.8e-75 253.7 0.0 2.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19674.1 - 1.3e-35 123.0 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19674.1 - 2.4e-07 30.3 0.1 8.5e-06 25.3 0.0 2.3 2 1 1 3 3 3 1 Kinase-like FTA2 PF13095.6 KFP19674.1 - 0.00097 18.8 0.1 0.48 10.0 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP19674.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP19674.1 - 0.0016 18.4 0.1 0.43 10.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cytokin-bind PF09265.10 KFP19674.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding TmoB PF06234.12 KFP19674.1 - 0.15 12.2 0.0 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Ge1_WD40 PF16529.5 KFP19675.1 - 7.1e-141 468.9 0.0 1.5e-140 467.8 0.0 1.5 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KFP19675.1 - 0.00034 21.3 3.4 0.0065 17.3 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ORF6C PF10552.9 KFP19675.1 - 0.0056 16.7 0.7 0.58 10.3 0.0 3.4 3 0 0 3 3 3 1 ORF6C domain TetR_C_11 PF16859.5 KFP19675.1 - 1.4 9.2 4.0 3.3 8.1 0.5 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain INTS5_N PF14837.6 KFP19675.1 - 2.1 7.9 6.9 5.7 6.5 0.7 2.5 1 1 1 2 2 2 0 Integrator complex subunit 5 N-terminus PIN_8 PF18476.1 KFP19675.1 - 4.1 7.2 16.8 8.2 6.2 3.1 3.5 1 1 2 3 3 3 0 PIN like domain NTF2 PF02136.20 KFP19676.1 - 5.4e-33 114.1 0.0 6.1e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KFP19676.1 - 0.073 13.5 0.0 0.088 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CENP-T_C PF15511.6 KFP19677.1 - 6.2e-30 103.5 0.2 7.5e-30 103.2 0.2 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFP19677.1 - 7.3e-09 35.9 0.1 9.5e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KFP19677.1 - 0.00026 21.4 0.1 0.00031 21.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP19677.1 - 0.00079 19.7 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KFP19677.1 - 0.021 14.8 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TSNAXIP1_N PF15739.5 KFP19678.1 - 3.3e-31 107.9 7.7 3.3e-31 107.9 7.7 3.8 3 1 1 4 4 4 1 Translin-associated factor X-interacting N-terminus ZapB PF06005.12 KFP19678.1 - 0.015 15.7 8.2 0.015 15.7 8.2 3.9 4 0 0 4 4 4 0 Cell division protein ZapB PI_PP_I PF18363.1 KFP19678.1 - 0.018 15.2 9.3 0.036 14.3 0.1 3.6 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain TPR_MLP1_2 PF07926.12 KFP19678.1 - 0.019 15.0 26.6 2.6 8.1 2.9 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein COMMD1_N PF17221.3 KFP19678.1 - 0.42 10.9 5.6 0.91 9.9 0.6 2.9 2 0 0 2 2 2 0 COMMD1 N-terminal domain DUF4446 PF14584.6 KFP19678.1 - 1 9.3 11.5 0.22 11.5 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DivIC PF04977.15 KFP19678.1 - 1.4 8.7 16.4 2.6 7.9 4.9 4.0 2 2 0 2 2 2 0 Septum formation initiator YabA PF06156.13 KFP19678.1 - 2.1 9.0 19.1 0.81 10.4 0.6 3.7 3 1 0 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 KFP19678.1 - 2.4 8.6 11.8 2.5 8.6 0.2 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KFP19678.1 - 4.9 6.4 21.9 1.3 8.3 5.4 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) Lectin_N PF03954.14 KFP19678.1 - 8.5 6.1 12.4 9.1 6.0 1.3 2.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain GAS PF13851.6 KFP19678.1 - 9.3 5.5 31.4 16 4.7 18.8 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KFP19678.1 - 9.3 6.3 28.8 1.3 9.1 5.9 3.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CLTH PF10607.9 KFP19679.1 - 9.5e-42 142.4 0.2 8.4e-41 139.3 0.2 2.0 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KFP19679.1 - 4.7e-26 91.3 0.2 4.7e-26 91.3 0.2 1.9 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 KFP19679.1 - 9.1e-06 25.5 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 LisH PARM PF17061.5 KFP19679.1 - 0.66 10.1 22.0 1.1 9.3 22.0 1.3 1 0 0 1 1 1 0 PARM Macoilin PF09726.9 KFP19679.1 - 1 7.8 9.4 1.3 7.5 9.4 1.1 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KFP19679.1 - 2.6 6.0 6.4 3.7 5.5 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KFP19679.1 - 3.1 6.5 5.7 4 6.1 5.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2374 PF09574.10 KFP19680.1 - 0.2 11.5 2.7 0.27 11.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) ARL2_Bind_BART PF11527.8 KFP19681.1 - 3e-33 114.4 8.3 3.6e-33 114.1 8.3 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART SF3A3 PF16837.5 KFP19681.1 - 0.86 10.2 4.6 2.5 8.6 0.1 2.8 2 2 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SPRY PF00622.28 KFP19682.1 - 3e-21 75.8 0.4 5.1e-21 75.0 0.4 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 KFP19682.1 - 5.6e-09 35.7 13.4 5.6e-09 35.7 13.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP19682.1 - 1.9e-05 24.4 10.1 6.3e-05 22.7 10.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Nefa_Nip30_N PF10187.9 KFP19683.1 - 6.4e-32 110.0 22.9 1.3e-31 109.1 22.9 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Copine PF07002.16 KFP19684.1 - 3.3e-88 294.8 0.0 4.9e-88 294.2 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 KFP19684.1 - 1.4e-25 89.6 0.0 1.3e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 KFP19684.1 - 1.4e-05 25.3 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus LBP_BPI_CETP_C PF02886.17 KFP19685.1 - 2e-27 96.2 0.9 3e-27 95.6 0.3 1.6 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 KFP19685.1 - 1.8e-26 92.7 0.1 5e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain ubiquitin PF00240.23 KFP19686.1 - 0.00037 20.2 0.3 0.00061 19.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family PRCC PF10253.9 KFP19686.1 - 0.027 15.3 0.1 0.045 14.5 0.1 1.4 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting BBIP10 PF14777.6 KFP19686.1 - 0.14 11.7 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 PB1 PF00564.24 KFP19687.1 - 7.8e-13 48.2 0.3 1.7e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ PF00595.24 KFP19687.1 - 2e-11 44.1 0.3 4.3e-11 43.0 0.2 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP19687.1 - 7.4e-08 32.1 0.1 3.4e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 PDZ domain Enkurin PF13864.6 KFP19688.1 - 1.9e-26 92.4 0.9 1.9e-26 92.4 0.9 2.8 3 0 0 3 3 3 1 Calmodulin-binding DUF2262 PF10020.9 KFP19688.1 - 0.095 13.1 0.0 0.095 13.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) SpoVR PF04293.13 KFP19688.1 - 1.3 7.7 6.8 0.19 10.4 1.1 1.9 2 0 0 2 2 2 0 SpoVR like protein BRICHOS PF04089.14 KFP19688.1 - 1.5 9.1 3.2 23 5.3 0.1 2.5 2 0 0 2 2 2 0 BRICHOS domain GFO_IDH_MocA PF01408.22 KFP19689.1 - 1.1e-14 55.3 0.0 5.8e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KFP19689.1 - 0.00083 19.9 0.0 0.0026 18.3 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFP19689.1 - 0.072 13.2 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CIAPIN1 PF05093.13 KFP19690.1 - 1.1e-22 80.3 16.2 2.3e-17 63.3 3.1 2.7 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_31 PF13847.6 KFP19690.1 - 3.6e-06 26.8 0.0 7.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP19690.1 - 3.9e-06 27.4 0.0 7.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP19690.1 - 0.00028 21.5 0.0 0.00054 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP19690.1 - 0.0015 19.2 0.0 0.003 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP19690.1 - 0.0036 17.2 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFP19690.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KFP19690.1 - 0.21 10.9 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Tat PF00539.18 KFP19690.1 - 6.5 7.0 13.3 0.1 12.8 1.8 2.3 1 1 1 2 2 2 0 Transactivating regulatory protein (Tat) COQ9 PF08511.11 KFP19691.1 - 1.6e-35 120.7 0.6 3.1e-35 119.8 0.3 1.6 2 0 0 2 2 2 1 COQ9 RNA_pol_A_bac PF01000.26 KFP19692.1 - 2.6e-40 137.3 0.0 3.6e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFP19692.1 - 4e-12 45.4 0.0 5.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IRS PF02174.17 KFP19693.1 - 1.6e-30 104.9 0.0 2.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Cytochrome_cB PF11783.8 KFP19693.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial PH PF00169.29 KFP19693.1 - 0.15 12.6 0.1 0.29 11.6 0.1 1.5 1 0 0 1 1 1 0 PH domain Myosin_tail_1 PF01576.19 KFP19694.1 - 2.5e-14 52.1 43.2 2.5e-14 52.1 43.2 2.0 1 1 1 2 2 2 2 Myosin tail PRKG1_interact PF15898.5 KFP19694.1 - 0.00079 20.3 12.2 0.00079 20.3 12.2 4.9 2 2 2 4 4 4 1 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 KFP19694.1 - 0.0011 17.9 59.0 0.0061 15.5 23.8 3.2 1 1 3 4 4 4 4 Spc7 kinetochore protein Taxilin PF09728.9 KFP19694.1 - 0.0025 17.0 57.9 0.31 10.2 47.1 2.5 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Filament PF00038.21 KFP19694.1 - 0.0058 16.3 52.2 0.16 11.5 16.4 2.7 1 1 1 2 2 2 2 Intermediate filament protein THOC7 PF05615.13 KFP19694.1 - 0.0077 16.5 16.7 0.0077 16.5 16.7 4.1 1 1 2 3 3 2 1 Tho complex subunit 7 ADIP PF11559.8 KFP19694.1 - 0.041 14.0 53.7 0.4 10.8 12.7 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KFP19694.1 - 0.087 13.4 68.3 0.32 11.5 13.9 4.2 1 1 1 3 3 3 0 Apg6 coiled-coil region Leu_zip PF15294.6 KFP19694.1 - 0.14 11.7 46.8 0.073 12.6 29.7 2.3 1 1 1 2 2 2 0 Leucine zipper ATG16 PF08614.11 KFP19694.1 - 0.3 11.3 58.8 1.7 8.8 23.4 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 KFP19694.1 - 0.49 8.5 42.3 0.2 9.8 6.5 3.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 KFP19694.1 - 0.77 10.2 56.3 0.12 12.8 23.9 3.3 1 1 2 3 3 3 0 Fez1 DUF4407 PF14362.6 KFP19694.1 - 1.8 7.8 36.2 46 3.2 13.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KFP19694.1 - 2.2 8.7 31.8 5.7 7.4 0.6 5.7 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 KFP19694.1 - 2.3 7.9 51.5 0.14 11.9 19.2 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 KFP19694.1 - 3 7.9 29.1 0.11 12.5 7.4 4.0 1 1 3 4 4 4 0 Laminin Domain II PspA_IM30 PF04012.12 KFP19694.1 - 3 7.3 48.5 0.021 14.4 9.5 3.5 1 1 2 3 3 3 0 PspA/IM30 family Cep57_MT_bd PF06657.13 KFP19694.1 - 3.1 8.3 43.7 0.37 11.3 0.6 5.6 1 1 4 5 5 5 0 Centrosome microtubule-binding domain of Cep57 NPV_P10 PF05531.12 KFP19694.1 - 3.2 8.3 20.8 0.098 13.1 1.4 4.9 1 1 3 4 4 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KFP19694.1 - 3.4 7.9 32.5 0.56 10.4 5.6 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 KFP19694.1 - 3.6 6.1 40.7 0.14 10.8 16.9 2.1 1 1 1 2 2 2 0 AAA domain HOOK PF05622.12 KFP19694.1 - 4.3 5.3 58.3 61 1.6 58.5 2.1 1 1 0 1 1 1 0 HOOK protein BRE1 PF08647.11 KFP19694.1 - 5 7.3 51.4 1.1 9.4 7.8 4.3 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 KFP19694.1 - 6.1 4.2 49.9 16 2.8 49.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 KFP19694.1 - 8.5 5.7 60.7 0.44 9.9 10.4 3.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding PLL PF18587.1 KFP19695.1 - 5.6e-52 175.4 0.1 1.5e-51 174.1 0.1 1.8 1 0 0 1 1 1 1 PTX/LNS-Like (PLL) domain 7tm_2 PF00002.24 KFP19695.1 - 5.8e-30 104.4 18.9 8.1e-30 103.9 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP19695.1 - 1.7e-13 50.8 5.3 1.7e-13 50.8 5.3 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 KFP19696.1 - 1.5e-34 119.4 23.9 2.1e-34 118.9 23.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KFP19696.1 - 4.4e-14 52.7 1.3 1.1e-13 51.5 1.3 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TRIQK PF15168.6 KFP19696.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.5 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Zona_pellucida PF00100.23 KFP19697.1 - 5e-50 170.7 1.0 6.2e-50 170.4 1.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 KFP19697.1 - 3.6e-06 27.2 4.0 3.6e-06 27.2 4.0 2.0 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 KFP19697.1 - 0.0051 17.1 6.9 0.013 15.9 6.9 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP19697.1 - 0.007 17.0 1.8 0.007 17.0 1.8 2.3 2 0 0 2 2 2 1 Human growth factor-like EGF cEGF PF12662.7 KFP19697.1 - 0.048 13.6 1.5 0.12 12.3 1.5 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP19697.1 - 0.21 11.8 6.3 0.51 10.6 6.3 1.7 1 0 0 1 1 1 0 EGF domain Katanin_con80 PF13925.6 KFP19699.1 - 6.1e-51 172.6 2.9 5.2e-50 169.6 2.9 2.2 1 1 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 KFP19699.1 - 1.2e-48 162.0 5.6 1.9e-10 41.1 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19699.1 - 2e-19 69.6 0.0 5.8e-05 23.3 0.0 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP19699.1 - 9e-06 25.7 0.0 0.0037 17.2 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFP19699.1 - 0.0041 15.8 0.1 14 4.2 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP19699.1 - 0.011 14.8 0.0 0.6 9.0 0.0 3.0 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ALS_ss_C PF10369.9 KFP19699.1 - 0.17 12.1 0.0 9.9 6.5 0.0 2.9 3 0 0 3 3 3 0 Small subunit of acetolactate synthase WD40_like PF17005.5 KFP19699.1 - 0.19 11.1 0.0 17 4.6 0.0 3.4 1 1 1 2 2 2 0 WD40-like domain Kinesin PF00225.23 KFP19700.1 - 7.1e-107 357.2 0.3 1.5e-106 356.2 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP19700.1 - 2.1e-46 157.6 0.0 7.5e-46 155.8 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding DUF812 PF05667.11 KFP19700.1 - 0.0037 16.2 16.6 0.0037 16.2 16.6 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF812) HOOK PF05622.12 KFP19700.1 - 0.25 9.4 28.1 0.61 8.2 4.0 2.2 2 0 0 2 2 2 0 HOOK protein AAA_22 PF13401.6 KFP19700.1 - 0.74 10.1 3.5 6.6 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain FPP PF05911.11 KFP19700.1 - 1.1 7.4 20.1 0.092 10.9 9.6 2.5 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil KxDL PF10241.9 KFP19700.1 - 1.8 8.9 24.1 0.44 10.9 6.0 4.1 2 1 2 4 4 4 0 Uncharacterized conserved protein HIP1_clath_bdg PF16515.5 KFP19700.1 - 3.4 8.3 36.0 0.32 11.6 2.3 4.3 2 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 KFP19700.1 - 6 7.5 9.6 2.9 8.5 0.1 3.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal IFT57 PF10498.9 KFP19700.1 - 9.7 5.0 18.4 5.9 5.8 14.8 2.2 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 cNMP_binding PF00027.29 KFP19701.1 - 3.1e-17 62.4 0.0 5.9e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-C2H2 PF00096.26 KFP19702.1 - 1.3e-57 189.2 150.5 2.6e-06 27.5 0.9 17.2 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP19702.1 - 7.9e-53 174.7 141.6 3.7e-10 39.8 0.7 17.5 18 0 0 18 18 18 13 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP19702.1 - 4.2e-38 126.7 135.7 0.0013 19.4 2.1 17.1 17 0 0 17 17 17 15 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP19702.1 - 4.6e-24 84.2 88.0 0.0011 19.1 0.1 15.0 15 0 0 15 15 15 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP19702.1 - 7.8e-15 54.7 97.6 0.016 15.6 0.6 14.9 15 0 0 15 15 15 9 Zinc-finger of C2H2 type BolA PF01722.18 KFP19702.1 - 2e-06 28.0 36.5 0.33 11.2 0.3 8.8 3 2 5 9 9 9 4 BolA-like protein zf-C2H2_6 PF13912.6 KFP19702.1 - 5.1e-05 23.2 1.6 5.1e-05 23.2 1.6 17.1 17 1 0 17 17 17 9 C2H2-type zinc finger MRP-S23 PF10484.9 KFP19702.1 - 0.016 15.5 0.0 75 3.6 0.0 4.9 3 2 1 4 4 4 0 Mitochondrial ribosomal protein S23 Antimicrobial_3 PF08025.11 KFP19702.1 - 0.18 11.8 1.0 39 4.3 0.1 4.0 3 0 0 3 3 3 0 Spider antimicrobial peptide UPF0728 PF15092.6 KFP19702.1 - 1.9 8.4 8.6 3.8 7.4 0.1 4.7 4 1 0 4 4 4 0 Uncharacterised protein family UPF0728 HVSL PF09749.9 KFP19703.1 - 9e-43 146.4 0.0 1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Peptidase_M10 PF00413.24 KFP19704.1 - 2.6e-59 199.6 0.0 4e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KFP19704.1 - 1.4e-52 175.4 19.7 1.9e-14 53.3 0.9 4.5 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KFP19704.1 - 6.9e-08 32.6 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KFP19704.1 - 0.0038 17.7 0.1 0.007 16.9 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFP19704.1 - 0.0085 15.7 0.6 1.3 8.6 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4953 PF16313.5 KFP19704.1 - 0.028 13.6 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 KFP19704.1 - 0.046 12.3 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_5 PF13688.6 KFP19704.1 - 0.054 13.7 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M54 PF07998.11 KFP19704.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 KFP19704.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF667 PF05018.13 KFP19705.1 - 1.1e-79 266.5 0.8 1.2e-79 266.3 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.25 KFP19707.1 - 6.7e-71 238.7 0.9 7.9e-71 238.5 0.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19707.1 - 7.8e-21 74.5 0.2 1.5e-20 73.6 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP19707.1 - 6.1e-10 39.4 0.0 1.4e-06 28.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP19707.1 - 0.00069 18.5 0.1 0.0062 15.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFP19707.1 - 0.0051 16.2 0.4 0.0087 15.4 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP19707.1 - 0.0059 16.2 0.2 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KFP19707.1 - 0.039 13.3 0.7 0.14 11.5 0.1 2.1 2 1 0 2 2 2 0 Kinase-like PAS_3 PF08447.12 KFP19707.1 - 0.076 13.3 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 PAS fold ABC1 PF03109.16 KFP19707.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF4201 PF13870.6 KFP19708.1 - 9.5e-32 110.2 24.5 9.5e-32 110.2 24.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF948 PF06103.11 KFP19708.1 - 0.26 11.6 6.0 0.33 11.2 0.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Flt3_lig PF02947.14 KFP19708.1 - 0.6 10.3 4.2 5 7.3 2.9 3.1 2 1 0 2 2 2 0 flt3 ligand Baculo_PEP_C PF04513.12 KFP19708.1 - 2.6 8.1 7.7 1.6 8.8 0.1 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KFP19708.1 - 4.4 7.4 20.8 0.26 11.3 0.8 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Ndr PF03096.14 KFP19709.1 - 3.8e-104 347.3 0.1 2.4e-103 344.7 0.1 1.9 1 1 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 KFP19709.1 - 0.063 12.9 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold TLV_coat PF00429.19 KFP19710.1 - 0.00056 18.7 0.2 0.00061 18.6 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Hexokinase_2 PF03727.16 KFP19712.1 - 1.1e-170 565.2 0.1 5.2e-87 291.2 0.1 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KFP19712.1 - 3.8e-148 490.4 0.3 4.8e-74 248.6 0.1 2.3 2 0 0 2 2 2 2 Hexokinase FGGY_N PF00370.21 KFP19712.1 - 0.067 12.7 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain BTB PF00651.31 KFP19713.1 - 3.7e-14 52.9 0.0 2.5e-13 50.2 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP19713.1 - 7.5e-07 29.2 0.2 2.2e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Annexin PF00191.20 KFP19714.1 - 8.9e-36 121.8 0.5 9.4e-26 89.7 0.1 2.0 2 0 0 2 2 2 2 Annexin Pkinase PF00069.25 KFP19715.1 - 2.5e-42 145.1 0.0 2.5e-42 145.1 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19715.1 - 6.5e-25 87.9 0.0 6.5e-25 87.9 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP19715.1 - 0.022 13.6 0.0 0.022 13.6 0.0 2.7 2 1 1 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 KFP19715.1 - 0.033 13.2 0.0 0.033 13.2 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KFP19715.1 - 0.06 13.3 0.3 0.06 13.3 0.3 3.5 2 2 2 4 4 4 0 Phosphotransferase enzyme family BMP2K_C PF15282.6 KFP19716.1 - 0.0065 16.4 0.1 0.0072 16.2 0.1 1.1 1 0 0 1 1 1 1 BMP-2-inducible protein kinase C-terminus BMP2K_C PF15282.6 KFP19717.1 - 5.9e-37 127.9 14.5 3.9e-33 115.4 11.2 3.2 2 1 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus Nfu_N PF08712.11 KFP19718.1 - 3.4e-34 116.8 0.0 5.8e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KFP19718.1 - 8.4e-26 89.9 0.1 1.2e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain SIS PF01380.22 KFP19719.1 - 4.1e-69 230.5 0.1 1.9e-36 124.8 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFP19719.1 - 2.6e-16 60.0 0.0 7.1e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFP19719.1 - 2e-12 47.1 0.0 4.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFP19719.1 - 0.00011 21.2 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KFP19719.1 - 0.00041 19.2 0.0 0.00085 18.1 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KFP19719.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 SIS domain Ant_C PF05586.11 KFP19720.1 - 1.5e-44 150.5 0.4 1.9e-44 150.2 0.4 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region RhoGAP PF00620.27 KFP19721.1 - 9.5e-45 152.1 2.0 8.9e-44 149.0 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KFP19721.1 - 4e-22 78.7 1.4 5.6e-22 78.2 0.1 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KFP19721.1 - 7.4e-06 26.2 0.7 7.8e-05 22.9 0.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFP19721.1 - 6.3e-05 23.4 4.1 0.0012 19.2 4.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Nsp1_C PF05064.13 KFP19721.1 - 0.031 14.1 10.7 0.23 11.3 11.2 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region PH_9 PF15410.6 KFP19721.1 - 0.045 14.1 2.8 0.39 11.1 0.1 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain CENP-F_leu_zip PF10473.9 KFP19721.1 - 0.048 13.7 21.2 0.097 12.7 21.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_F PF12259.8 KFP19721.1 - 0.31 9.5 8.9 0.43 9.1 8.9 1.1 1 0 0 1 1 1 0 Baculovirus F protein Cnn_1N PF07989.11 KFP19721.1 - 0.68 10.1 17.2 0.72 10.0 14.7 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CTP_transf_1 PF01148.20 KFP19722.1 - 2.2e-87 293.2 21.9 2.7e-87 292.9 21.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PCNA_C PF02747.15 KFP19723.1 - 4e-64 214.5 0.0 5.5e-64 214.1 0.0 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KFP19723.1 - 2.2e-17 62.9 0.4 5.7e-17 61.6 0.4 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 KFP19723.1 - 4.1e-05 22.8 0.0 5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 FmdE PF02663.14 KFP19723.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF872 PF05915.12 KFP19724.1 - 4.7e-21 75.1 0.4 5.2e-21 74.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.6 KFP19724.1 - 0.0043 16.8 0.7 0.14 11.9 0.7 2.0 1 1 0 1 1 1 1 Neurensin DUF2207 PF09972.9 KFP19724.1 - 0.0088 14.9 0.6 0.01 14.7 0.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 KFP19724.1 - 0.05 13.9 0.1 0.069 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF308 PF03729.13 KFP19724.1 - 0.18 12.1 11.2 0.79 10.1 9.6 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Saf_2TM PF18303.1 KFP19724.1 - 1.4 8.5 4.4 1 8.9 0.6 2.0 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain Xan_ur_permease PF00860.20 KFP19725.1 - 6e-92 308.3 20.6 8.7e-92 307.8 20.6 1.2 1 0 0 1 1 1 1 Permease family Nore1-SARAH PF16517.5 KFP19726.1 - 7.8e-16 57.7 6.1 2.2e-15 56.2 6.1 1.8 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 KFP19726.1 - 6.4e-13 49.2 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 KFP19726.1 - 0.021 15.1 0.1 0.059 13.7 0.0 1.8 1 1 1 2 2 2 0 Ras-binding domain of Byr2 DUF4125 PF13526.6 KFP19726.1 - 0.037 13.7 0.2 0.093 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) Prominin PF05478.11 KFP19727.1 - 9.2e-134 447.3 0.0 1e-133 447.1 0.0 1.0 1 0 0 1 1 1 1 Prominin USP8_dimer PF08969.11 KFP19728.1 - 7.2e-21 74.5 0.4 7.2e-21 74.5 0.4 2.0 1 1 1 2 2 2 1 USP8 dimerisation domain JAB PF01398.21 KFP19728.1 - 2.3e-19 69.5 0.1 2.3e-19 69.5 0.1 2.0 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KFP19728.1 - 3.1e-07 30.2 0.5 2.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain MIT PF04212.18 KFP19728.1 - 0.00073 19.6 0.2 0.00073 19.6 0.2 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Actin PF00022.19 KFP19729.1 - 2.2e-131 438.3 0.0 8.2e-131 436.4 0.0 1.7 1 1 0 1 1 1 1 Actin dNK PF01712.19 KFP19730.1 - 1.6e-22 80.4 0.0 1.9e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFP19730.1 - 0.14 12.7 0.1 0.18 12.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain Tet_JBP PF12851.7 KFP19731.1 - 7.5e-79 265.5 0.3 8.9e-79 265.3 0.3 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily bZIP_Maf PF03131.17 KFP19731.1 - 0.38 11.3 5.8 2.6 8.6 2.6 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor THF_DHG_CYH_C PF02882.19 KFP19732.1 - 1.2e-63 213.2 2.5 1.7e-63 212.7 2.5 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFP19732.1 - 6.2e-40 136.1 0.1 9e-40 135.6 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 KFP19732.1 - 0.028 13.7 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tetraspanin PF00335.20 KFP19733.1 - 8.1e-48 163.1 7.6 9.4e-48 162.9 7.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3902 PF13042.6 KFP19733.1 - 0.35 10.5 9.0 0.16 11.5 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) ABC2_membrane_3 PF12698.7 KFP19733.1 - 1.4 8.0 13.1 4.2 6.4 10.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2371 PF10177.9 KFP19733.1 - 2.2 8.5 5.1 7.8 6.7 0.5 2.8 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) 7tm_1 PF00001.21 KFP19734.1 - 9.4e-56 189.0 23.2 1.3e-55 188.6 23.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19734.1 - 1.6e-07 31.0 22.1 2.1e-07 30.6 22.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP19734.1 - 3.6e-06 26.9 7.3 3.6e-06 26.9 7.3 2.5 2 1 0 3 3 3 1 Olfactory receptor Cnd2 PF05786.14 KFP19735.1 - 7.5e-16 58.0 0.0 7.6e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Cnd2 PF05786.14 KFP19736.1 - 4.4e-74 250.5 0.9 5.5e-74 250.2 0.9 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Pkinase PF00069.25 KFP19737.1 - 1.8e-30 106.2 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19737.1 - 3.7e-20 72.3 0.0 4.1e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP19737.1 - 1.3e-06 27.5 0.0 1.3e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP19737.1 - 2.7e-05 23.6 0.0 3.1e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Lectin_leg-like PF03388.13 KFP19741.1 - 2.9e-62 210.0 0.0 8.4e-62 208.5 0.0 1.6 1 1 0 1 1 1 1 Legume-like lectin family PMP1_2 PF08114.11 KFP19741.1 - 0.0017 18.0 0.2 0.0035 17.0 0.2 1.5 1 0 0 1 1 1 1 ATPase proteolipid family DUF4134 PF13572.6 KFP19741.1 - 0.042 14.1 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Col_cuticle_N PF01484.17 KFP19741.1 - 0.1 12.7 0.8 0.18 11.9 0.8 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 KFP19743.1 - 3.7e-34 118.3 0.0 6.3e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19743.1 - 1.3e-31 109.9 0.0 2.1e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFP19743.1 - 6.1e-06 27.2 12.5 6.1e-06 27.2 12.5 2.2 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP19743.1 - 2.2e-05 23.4 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KFP19743.1 - 0.034 13.8 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP19743.1 - 0.054 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PWWP PF00855.17 KFP19744.1 - 0.00015 22.1 0.0 0.00037 20.8 0.0 1.7 1 0 0 1 1 1 1 PWWP domain MBD PF01429.19 KFP19744.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain E_Pc_C PF06752.12 KFP19745.1 - 5.1e-68 229.6 26.1 1e-67 228.6 26.1 1.5 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.9 KFP19745.1 - 1.4e-14 54.8 1.6 1.4e-14 54.8 1.6 4.0 3 1 0 3 3 3 1 Enhancer of polycomb-like CAF1A PF12253.8 KFP19745.1 - 0.047 13.9 0.8 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Kinesin PF00225.23 KFP19746.1 - 9.7e-111 369.9 0.3 9.7e-111 369.9 0.3 2.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP19746.1 - 1e-22 80.7 0.0 1e-22 80.7 0.0 3.6 3 1 1 4 4 4 1 Microtubule binding DASH_Dam1 PF08653.10 KFP19746.1 - 0.38 10.6 12.4 3.3 7.6 0.6 4.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 PTSIIB_sorb PF03830.15 KFP19746.1 - 1.1 9.5 8.2 1.8 8.8 0.1 3.8 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component DUF1799 PF08809.11 KFP19746.1 - 1.7 8.8 4.0 3.3 7.9 0.3 3.1 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) UPAR_LY6_2 PF16975.5 KFP19747.1 - 2.3e-54 182.1 16.4 2.8e-54 181.8 16.4 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 UPAR_LY6_2 PF16975.5 KFP19748.1 - 1.5e-51 173.1 12.1 1.8e-51 172.8 12.1 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Toxin_TOLIP PF00087.21 KFP19748.1 - 1.8 8.9 19.8 4.1 7.7 19.8 1.6 1 1 0 1 1 1 0 Snake toxin and toxin-like protein MMADHC PF10229.9 KFP19749.1 - 3.5e-133 443.5 0.0 4e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Misat_Tub_SegII PF10644.9 KFP19749.1 - 0.053 13.8 0.2 0.096 13.0 0.2 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tiam_CC_Ex PF18385.1 KFP19749.1 - 0.078 13.4 0.2 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain Ras PF00071.22 KFP19750.1 - 9.3e-19 67.6 0.0 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP19750.1 - 0.0027 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NID PF07292.13 KFP19751.1 - 1.5e-12 48.0 0.1 2.4e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_1 PF00076.22 KFP19751.1 - 0.0096 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 KFP19752.1 - 4.2e-59 197.2 0.0 2.6e-30 104.9 0.1 2.0 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) DUF237 PF03072.14 KFP19752.1 - 0.03 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF237) Lamprin PF06403.11 KFP19753.1 - 0.002 18.1 3.4 0.011 15.7 3.4 1.8 1 1 0 1 1 1 1 Lamprin Chorion_1 PF01723.16 KFP19753.1 - 0.19 11.7 12.4 2.5 8.0 12.4 2.0 1 1 0 1 1 1 0 Chorion protein CUB PF00431.20 KFP19754.1 - 1.1e-35 122.3 0.2 2e-35 121.4 0.2 1.4 1 0 0 1 1 1 1 CUB domain Xlink PF00193.17 KFP19754.1 - 6.9e-30 103.3 0.4 1.1e-29 102.6 0.4 1.3 1 0 0 1 1 1 1 Extracellular link domain Rif1_N PF12231.8 KFP19755.1 - 4.2e-77 259.7 5.6 1.1e-76 258.4 5.6 1.7 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Arf PF00025.21 KFP19756.1 - 1.9e-64 216.3 0.9 2.1e-64 216.2 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP19756.1 - 2.4e-15 56.8 0.3 3.2e-15 56.4 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP19756.1 - 3.3e-14 52.8 0.4 3.6e-14 52.7 0.4 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP19756.1 - 3.5e-12 46.1 0.2 4.3e-12 45.8 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP19756.1 - 1.1e-08 34.7 1.5 1.6e-06 27.5 0.6 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KFP19756.1 - 2.7e-07 30.6 0.1 3.8e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP19756.1 - 5.8e-07 29.1 0.4 6.9e-07 28.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFP19756.1 - 0.0031 17.1 0.4 0.016 14.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KFP19756.1 - 0.021 14.8 0.2 0.079 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KFP19756.1 - 0.037 13.5 0.9 0.2 11.2 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TPM_phosphatase PF04536.14 KFP19756.1 - 0.072 13.3 0.2 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 TPM domain Guanylate_kin PF00625.21 KFP19757.1 - 1.5e-46 158.4 0.1 2.5e-46 157.6 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase VGCC_beta4Aa_N PF12052.8 KFP19757.1 - 1.5e-22 79.4 6.3 3.5e-22 78.2 6.3 1.7 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.28 KFP19757.1 - 0.001 18.6 0.0 0.0046 16.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP19757.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 KFP19757.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain GAS PF13851.6 KFP19758.1 - 2.9e-74 248.8 31.0 2.9e-74 248.8 31.0 3.1 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding DUF3573 PF12097.8 KFP19758.1 - 3.8 6.2 5.7 3.4 6.4 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3584 PF12128.8 KFP19758.1 - 5.9 4.3 55.6 8.1 3.8 55.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tubulin_C PF03953.17 KFP19759.1 - 5.6e-43 146.1 0.1 9.2e-43 145.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KFP19759.1 - 1.3e-41 143.0 0.0 2.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KFP19759.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KFP19759.1 - 0.03 13.5 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Se-cys_synth_N PF12390.8 KFP19760.1 - 0.013 15.7 0.1 0.05 13.8 0.1 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Tcf25 PF04910.14 KFP19762.1 - 9.2e-123 409.8 4.3 1.2e-122 409.4 4.3 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KFP19762.1 - 0.085 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Adaptin_binding PF10199.9 KFP19762.1 - 0.58 10.8 12.5 1.2 9.7 10.6 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SPT6_acidic PF14632.6 KFP19762.1 - 1.9 9.1 17.6 0.36 11.4 13.7 1.9 2 0 0 2 2 2 0 Acidic N-terminal SPT6 GET2 PF08690.10 KFP19762.1 - 4.2 7.0 8.9 3.6 7.2 5.6 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 7tm_4 PF13853.6 KFP19763.1 - 4.1e-44 151.4 15.0 4.8e-44 151.2 15.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19763.1 - 9.4e-27 94.0 18.2 1.9e-26 93.0 18.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP19764.1 - 1.3e-49 169.4 10.3 1.5e-49 169.2 10.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19764.1 - 4.6e-30 104.8 10.1 6.7e-30 104.3 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19764.1 - 9.8e-05 21.9 10.5 0.00014 21.3 10.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CTNNB1_binding PF08347.11 KFP19765.1 - 4.5e-38 131.5 7.8 4.5e-38 131.5 7.8 2.6 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.19 KFP19765.1 - 1.4e-22 79.8 1.0 3.1e-22 78.8 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP19765.1 - 1.3e-08 35.3 2.0 3.1e-08 34.1 2.0 1.6 1 0 0 1 1 1 1 HMG-box domain V-SNARE_C PF12352.8 KFP19766.1 - 5.8e-22 77.7 6.8 9.5e-21 73.9 6.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KFP19766.1 - 6.5e-19 68.1 4.0 6.5e-19 68.1 4.0 2.4 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.12 KFP19766.1 - 0.00072 19.6 0.6 0.044 13.8 0.0 2.2 2 0 0 2 2 2 1 Laminin Domain II Peptidase_S46 PF10459.9 KFP19766.1 - 0.033 12.8 5.7 0.037 12.7 5.7 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF5344 PF17279.2 KFP19766.1 - 0.055 14.1 1.2 2 9.1 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5344) Mer2 PF09074.10 KFP19766.1 - 0.055 13.3 3.0 2.8 7.7 0.1 2.1 1 1 1 2 2 2 0 Mer2 DUF1664 PF07889.12 KFP19766.1 - 0.072 13.1 3.0 1.2 9.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SKA2 PF16740.5 KFP19766.1 - 0.17 11.7 0.4 0.17 11.7 0.4 2.6 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Sec20 PF03908.13 KFP19766.1 - 0.18 11.7 1.1 0.87 9.5 0.2 2.3 2 1 0 2 2 2 0 Sec20 DegQ PF08181.11 KFP19766.1 - 0.38 10.9 4.1 0.45 10.7 1.7 2.3 3 0 0 3 3 3 0 DegQ (SacQ) family MetOD2 PF18548.1 KFP19766.1 - 0.44 10.7 7.9 3.7 7.7 1.5 2.3 2 0 0 2 2 2 0 Metanogen output domain 2 Exonuc_VII_L PF02601.15 KFP19766.1 - 0.66 9.5 10.1 2.5 7.6 10.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 KFP19766.1 - 2.4 7.9 7.0 12 5.6 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF2203 PF09969.9 KFP19766.1 - 4.6 8.0 6.3 2.1e+02 2.7 6.3 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) AMP-binding PF00501.28 KFP19767.1 - 2.2e-113 379.1 0.0 2.8e-113 378.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP19767.1 - 0.00018 22.4 0.2 0.00056 20.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zona_pellucida PF00100.23 KFP19768.1 - 1.7e-33 116.5 7.1 2.1e-33 116.2 7.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Acyltransferase PF01553.21 KFP19769.1 - 9.3e-23 80.3 0.0 2.2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase 7tm_1 PF00001.21 KFP19770.1 - 2.6e-78 263.0 0.0 3.4e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19770.1 - 1.6e-10 40.8 12.6 1.5e-06 27.8 4.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP19770.1 - 3e-07 30.5 7.1 8.8e-06 25.7 4.3 2.3 2 0 0 2 2 2 2 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP19770.1 - 1.5e-05 24.7 12.8 1.5e-05 24.7 12.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SSM PF04612.12 KFP19770.1 - 0.21 11.6 0.1 0.4 10.7 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M LRR_8 PF13855.6 KFP19771.1 - 1.2e-57 191.5 67.6 1.3e-11 44.0 7.1 8.7 4 3 5 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KFP19771.1 - 2.7e-39 132.5 74.6 1.6e-06 28.3 3.6 10.7 4 2 12 16 16 16 16 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP19771.1 - 2.5e-12 46.7 35.9 0.0018 17.8 2.0 5.8 2 2 4 6 6 6 5 Leucine-rich repeat LRR_5 PF13306.6 KFP19771.1 - 9.3e-07 28.9 3.6 0.083 12.9 0.8 4.5 1 1 5 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP19771.1 - 7.8e-06 25.7 62.6 4.2 8.3 0.7 17.1 18 2 0 18 18 18 2 Leucine Rich Repeat HERV-K_REC PF15695.5 KFP19771.1 - 0.076 13.1 1.5 2.7 8.1 0.1 3.5 3 0 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 RsmF_methylt_CI PF17126.5 KFP19771.1 - 0.25 11.4 1.7 25 5.0 0.0 4.8 4 2 1 6 6 6 0 RsmF rRNA methyltransferase first C-terminal domain SUFU_C PF12470.8 KFP19771.1 - 0.7 9.9 2.7 0.87 9.6 0.6 2.1 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain MA3 PF02847.17 KFP19772.1 - 1.4e-48 163.5 0.3 1.2e-25 89.7 0.3 2.1 2 0 0 2 2 2 2 MA3 domain DnaB_2 PF07261.11 KFP19772.1 - 0.048 13.4 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment HABP4_PAI-RBP1 PF04774.15 KFP19772.1 - 0.071 14.0 3.6 0.1 13.5 0.0 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family HAP1_N PF04849.13 KFP19773.1 - 0.0074 15.5 1.3 0.0095 15.2 1.3 1.3 1 1 0 1 1 1 1 HAP1 N-terminal conserved region zf-U1 PF06220.12 KFP19773.1 - 0.012 15.4 2.6 0.02 14.7 2.6 1.3 1 0 0 1 1 1 0 U1 zinc finger NACHT_N PF17100.5 KFP19773.1 - 0.082 12.7 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase zf-C2H2_jaz PF12171.8 KFP19773.1 - 0.13 12.6 2.9 0.3 11.4 2.9 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SMC_N PF02463.19 KFP19774.1 - 1.7e-63 214.0 23.5 3.4e-63 213.0 23.5 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFP19774.1 - 3.7e-21 75.6 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KFP19774.1 - 2.3e-12 47.3 13.0 2.3e-12 47.3 13.0 5.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 KFP19774.1 - 7.3e-11 42.4 20.6 3.4e-06 27.1 0.0 5.1 5 1 0 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFP19774.1 - 1e-08 35.9 47.0 1e-08 35.9 47.0 8.0 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 KFP19774.1 - 0.0041 16.8 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Muted PF14942.6 KFP19774.1 - 0.0065 16.8 11.7 0.0065 16.8 11.7 8.3 2 2 6 8 8 8 1 Organelle biogenesis, Muted-like protein ABC_tran PF00005.27 KFP19774.1 - 1.4 9.4 0.0 1.4 9.4 0.0 7.1 2 2 2 4 4 4 0 ABC transporter DSPc PF00782.20 KFP19775.1 - 2.5e-45 153.5 0.1 3.3e-45 153.1 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP19775.1 - 2.1e-05 24.2 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFP19775.1 - 0.019 15.3 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 KFP19775.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SMN PF06003.12 KFP19776.1 - 2.5e-17 63.0 5.3 3.1e-17 62.7 3.9 1.9 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KFP19776.1 - 0.0001 22.3 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 Tudor domain HLH PF00010.26 KFP19777.1 - 9e-14 51.2 0.6 8.1e-12 44.9 0.6 2.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KASH_CCD PF14662.6 KFP19777.1 - 0.00021 21.2 2.3 0.00036 20.4 2.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 KFP19777.1 - 0.12 13.0 4.0 0.53 10.9 3.7 2.1 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 KFP19777.1 - 0.43 10.4 3.5 1 9.2 3.5 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KFP19777.1 - 0.5 10.9 8.7 1 9.9 8.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CCDC106 PF15794.5 KFP19777.1 - 2.1 8.0 14.2 8.4 6.0 14.2 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Aldolase_II PF00596.21 KFP19778.1 - 5.8e-38 130.7 0.0 9.2e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_M24 PF00557.24 KFP19779.1 - 1e-45 156.1 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KFP19779.1 - 1.3e-45 155.4 0.0 2e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KFP19779.1 - 5.8e-24 83.9 0.4 3.2e-23 81.6 0.0 2.5 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KFP19779.1 - 2.7e-14 54.0 0.0 6e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Sortilin-Vps10 PF15902.5 KFP19780.1 - 5.6e-106 355.0 0.9 2.2e-105 353.1 0.1 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFP19780.1 - 6.4e-38 130.8 6.3 1e-37 130.1 6.3 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PKD PF00801.20 KFP19780.1 - 1.1e-17 63.6 3.1 2.6e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 PKD domain BNR PF02012.20 KFP19780.1 - 0.14 12.2 19.6 1.5 9.1 0.6 6.7 7 0 0 7 7 7 0 BNR/Asp-box repeat BNR_6 PF15899.5 KFP19780.1 - 0.43 10.8 3.4 94 3.5 0.0 4.7 4 0 0 4 4 4 0 BNR-Asp box repeat Mab-21 PF03281.14 KFP19782.1 - 3.8e-22 78.9 1.6 1.1e-20 74.1 1.7 2.3 1 1 0 1 1 1 1 Mab-21 protein CemA PF03040.14 KFP19782.1 - 0.19 11.6 1.2 0.32 10.9 1.2 1.3 1 0 0 1 1 1 0 CemA family GST_N_3 PF13417.6 KFP19783.1 - 2.9e-10 40.4 0.0 6.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP19783.1 - 5.4e-09 36.1 0.1 1e-08 35.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP19783.1 - 1.6e-08 34.4 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP19783.1 - 2.5e-07 30.8 0.1 3.9e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP19783.1 - 2.6e-07 30.8 0.0 7.6e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFP19783.1 - 1.9e-05 24.9 0.1 3.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KFP19783.1 - 0.00023 21.7 0.0 0.00035 21.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KFP19783.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Mei5 PF10376.9 KFP19786.1 - 7.2e-55 186.1 2.2 8.2e-55 185.9 2.2 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein Mei5_like PF17021.5 KFP19786.1 - 0.012 15.7 0.3 0.027 14.5 0.3 1.5 1 1 0 1 1 1 0 Putative double-strand recombination repair-like PKK PF12474.8 KFP19787.1 - 6.7e-78 259.6 102.5 2e-41 141.4 43.1 7.9 7 2 0 7 7 7 2 Polo kinase kinase Pkinase PF00069.25 KFP19787.1 - 5e-68 229.3 0.0 5e-68 229.3 0.0 3.9 4 1 0 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19787.1 - 8.5e-48 162.9 0.0 8.5e-48 162.9 0.0 2.8 3 1 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 KFP19787.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.7 3 1 1 4 4 4 0 Phosphotransferase enzyme family STN1_2 PF09170.10 KFP19788.1 - 7.4e-68 228.2 0.5 1.5e-67 227.2 0.5 1.6 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.25 KFP19788.1 - 3.4e-09 36.6 0.1 6.9e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 KFP19788.1 - 4e-08 32.5 0.3 1.9e-07 30.3 0.3 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DUF4364 PF14277.6 KFP19788.1 - 0.072 12.8 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) HTH_45 PF14947.6 KFP19788.1 - 0.083 12.9 0.0 1.8 8.6 0.0 2.7 2 1 1 3 3 3 0 Winged helix-turn-helix RMI2 PF16100.5 KFP19788.1 - 0.1 12.4 0.2 18 5.1 0.1 2.3 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 PX PF00787.24 KFP19789.1 - 2.5e-12 46.8 0.1 2.8e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 KFP19790.1 - 1.4e-10 41.4 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PB1 PF00564.24 KFP19790.1 - 1.4e-10 40.9 0.0 3.2e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ_6 PF17820.1 KFP19790.1 - 3.3e-09 36.4 0.0 6.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP19790.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 PDZ domain BLOC1_2 PF10046.9 KFP19791.1 - 0.0078 16.5 0.4 0.061 13.6 0.1 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 KFP19791.1 - 0.013 15.3 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 AIP3 PF03915.13 KFP19791.1 - 0.032 13.3 0.3 0.052 12.6 0.3 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF5063 PF16702.5 KFP19791.1 - 0.054 13.9 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) DUF16 PF01519.16 KFP19791.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 CLZ PF16526.5 KFP19791.1 - 0.083 13.3 0.0 7.7 7.0 0.0 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAP206 PF12018.8 KFP19791.1 - 0.099 12.1 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function FlaC_arch PF05377.11 KFP19791.1 - 0.11 12.8 0.6 7.2 7.1 0.0 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_I PF06008.14 KFP19791.1 - 0.12 12.1 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain I SHE3 PF17078.5 KFP19791.1 - 0.12 12.1 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4200 PF13863.6 KFP19791.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CAP PF00188.26 KFP19792.1 - 2.4e-22 80.1 0.8 3.1e-22 79.8 0.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ifi-6-16 PF06140.13 KFP19793.1 - 2.2e-24 85.1 16.1 8.9e-13 48.0 8.0 2.0 1 1 1 2 2 2 2 Interferon-induced 6-16 family Glycos_transf_1 PF00534.20 KFP19794.1 - 1.6e-39 135.2 0.0 2.3e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFP19794.1 - 8.4e-19 68.3 0.0 1.2e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFP19794.1 - 4.3e-05 23.6 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KFP19794.1 - 0.00015 22.1 0.0 0.00043 20.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1796 PF08795.10 KFP19794.1 - 0.049 13.6 0.3 0.94 9.4 0.3 2.6 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Sec61_beta PF03911.16 KFP19795.1 - 4.1e-20 71.5 0.0 4.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family zf-C4 PF00105.18 KFP19796.1 - 3.6e-31 107.4 18.3 6.4e-31 106.6 18.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP19796.1 - 1.9e-19 70.1 0.0 3.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNARE PF05739.19 KFP19797.1 - 1.9e-06 27.8 0.2 3.7e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Phage_holin_3_6 PF07332.11 KFP19797.1 - 0.01 15.9 1.7 0.025 14.6 1.7 1.7 1 1 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SlyX PF04102.12 KFP19797.1 - 0.017 15.8 2.0 0.29 11.8 0.1 2.7 2 0 0 2 2 2 0 SlyX DUF585 PF04522.12 KFP19797.1 - 0.058 13.0 0.0 0.46 10.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF585) ThrE PF06738.12 KFP19797.1 - 0.09 12.1 0.2 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative threonine/serine exporter Red1 PF07964.11 KFP19797.1 - 0.11 10.7 2.7 0.054 11.7 0.9 1.3 2 0 0 2 2 2 0 Rec10 / Red1 IncD PF17628.2 KFP19797.1 - 0.17 11.7 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Inclusion membrane protein D Thioredoxin_6 PF13848.6 KFP19798.1 - 2.8e-47 161.0 0.1 3.8e-43 147.6 0.1 2.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KFP19798.1 - 3.3e-21 75.2 0.0 8.4e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.17 KFP19798.1 - 3.1e-07 29.8 0.1 5.2e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 KFP19798.1 - 2.6e-05 23.7 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFP19798.1 - 0.00046 20.6 0.1 0.0018 18.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KFP19798.1 - 0.00066 19.6 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KFP19798.1 - 0.0059 16.9 0.2 0.091 13.1 0.1 2.5 1 1 1 2 2 2 1 Thioredoxin-like Ank_2 PF12796.7 KFP19799.1 - 2.4e-88 290.8 19.7 1.1e-16 61.1 0.0 8.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP19799.1 - 4e-70 231.3 18.5 1.3e-11 44.7 0.2 11.2 5 2 6 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 KFP19799.1 - 4.3e-63 207.2 24.2 4e-05 23.9 0.1 15.7 16 0 0 16 16 16 14 Ankyrin repeat Ank_3 PF13606.6 KFP19799.1 - 8.5e-63 200.9 18.3 0.00044 20.5 0.0 15.7 16 0 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.6 KFP19799.1 - 3.5e-61 202.5 22.0 1.1e-09 38.3 0.1 11.8 5 4 7 12 12 12 12 Ankyrin repeats (many copies) IQ PF00612.27 KFP19799.1 - 3.2e-08 32.7 6.1 0.0031 17.1 0.3 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ipi1_N PF12333.8 KFP19800.1 - 2.6e-23 82.5 1.1 2.6e-23 82.5 1.1 3.6 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 KFP19800.1 - 0.031 14.9 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFP19800.1 - 0.042 14.4 0.1 0.89 10.1 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat DUF2474 PF10617.9 KFP19800.1 - 1.4 8.8 5.0 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) zf-C2H2_jaz PF12171.8 KFP19801.1 - 0.00032 20.9 1.3 0.00032 20.9 1.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP19801.1 - 0.001 19.4 2.2 0.001 19.4 2.2 3.5 3 1 0 3 3 3 1 Zinc-finger of C2H2 type PNISR PF15996.5 KFP19801.1 - 0.1 12.9 17.1 0.19 12.0 17.1 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Myb_DNA-bind_5 PF13873.6 KFP19802.1 - 4.7e-23 81.1 2.1 4.7e-23 81.1 2.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFP19802.1 - 0.0033 17.7 4.0 0.0033 17.7 4.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like RecU PF03838.14 KFP19802.1 - 0.53 10.3 7.4 0.15 12.0 1.8 2.2 2 1 0 2 2 2 0 Recombination protein U ALMT PF11744.8 KFP19802.1 - 5.8 5.6 9.9 7.6 5.2 9.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PAS PF00989.25 KFP19803.1 - 4.9e-12 45.9 0.0 9.8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KFP19803.1 - 9.5e-06 25.8 0.3 0.0091 16.3 0.1 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP19803.1 - 1.4e-05 24.9 0.1 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_11 PF14598.6 KFP19803.1 - 1.6e-05 25.0 0.2 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 KFP19803.1 - 0.0087 16.3 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 PAS domain Herpes_U5 PF05999.11 KFP19803.1 - 0.075 11.8 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family EF-hand_7 PF13499.6 KFP19805.1 - 4.5e-24 84.7 1.5 2.8e-11 43.7 0.7 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KFP19805.1 - 1.6e-22 77.3 9.4 3e-07 29.5 0.1 5.3 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KFP19805.1 - 4.7e-21 72.9 5.6 4.2e-07 29.4 0.1 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KFP19805.1 - 6.4e-20 70.8 4.0 1.8e-06 27.7 0.1 4.5 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KFP19805.1 - 1.9e-12 46.0 4.2 0.00034 20.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KFP19805.1 - 0.0067 16.7 0.1 0.58 10.5 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain WWE PF02825.20 KFP19805.1 - 0.0089 16.6 0.3 0.38 11.4 0.2 2.5 2 1 0 2 2 2 1 WWE domain EF-hand_2 PF09068.11 KFP19805.1 - 0.055 13.6 0.0 2.9 8.0 0.0 2.5 2 1 0 2 2 2 0 EF hand Alpha_adaptin_C PF02296.16 KFP19805.1 - 0.099 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Sec6 PF06046.13 KFP19806.1 - 4.2e-159 530.6 14.2 6.4e-159 530.0 14.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Ago_N_1 PF18351.1 KFP19806.1 - 0.0085 16.5 1.0 0.055 13.9 0.0 2.8 2 1 1 3 3 3 1 Fungal Argonaute N-terminal domain NPV_P10 PF05531.12 KFP19806.1 - 0.37 11.3 4.8 12 6.4 4.8 3.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BORCS8 PF10167.9 KFP19806.1 - 2.8 7.9 7.3 0.46 10.4 0.9 2.9 4 0 0 4 4 4 0 BLOC-1-related complex sub-unit 8 DHC_N1 PF08385.12 KFP19807.1 - 2.5e-57 194.8 2.3 2.7e-57 194.7 2.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 FerA PF08165.11 KFP19807.1 - 0.017 15.0 1.6 0.59 10.1 0.0 2.9 3 0 0 3 3 3 0 FerA (NUC095) domain Proteasom_PSMB PF10508.9 KFP19807.1 - 0.035 12.6 0.3 0.059 11.9 0.2 1.4 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit DCX PF03607.17 KFP19807.1 - 0.035 14.2 0.1 4.2 7.6 0.1 2.6 1 1 0 1 1 1 0 Doublecortin Rab5-bind PF09311.11 KFP19807.1 - 0.11 11.9 1.7 0.15 11.5 1.7 1.2 1 0 0 1 1 1 0 Rabaptin-like protein PTRF_SDPR PF15237.6 KFP19808.1 - 2.5e-92 309.0 17.4 3.6e-92 308.4 17.4 1.2 1 0 0 1 1 1 1 PTRF/SDPR family DUF1664 PF07889.12 KFP19808.1 - 0.0098 15.9 7.2 0.0098 15.9 7.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) ZnuA PF01297.17 KFP19808.1 - 0.051 13.0 2.1 0.088 12.2 2.1 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic MCPsignal PF00015.21 KFP19808.1 - 0.49 10.2 16.5 0.069 13.0 2.5 2.9 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Hormone_1 PF00103.20 KFP19808.1 - 0.75 9.5 4.2 1.8 8.3 0.7 2.7 2 1 1 3 3 3 0 Somatotropin hormone family DUF948 PF06103.11 KFP19808.1 - 1.3 9.3 4.4 9.2 6.6 3.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Kazal_2 PF07648.15 KFP19809.1 - 9.5e-20 70.5 25.1 1.7e-11 44.0 6.1 3.6 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP19809.1 - 2.5e-13 49.8 27.7 8.5e-08 32.1 7.7 3.7 2 2 1 3 3 3 2 Kazal-type serine protease inhibitor domain DUF3844 PF12955.7 KFP19809.1 - 0.0042 17.2 1.8 0.0042 17.2 1.8 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3844) EphA2_TM PF14575.6 KFP19809.1 - 0.02 15.8 1.1 0.037 14.9 0.3 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.13 KFP19809.1 - 0.084 12.8 0.3 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Zip PF02535.22 KFP19810.1 - 4.7e-97 325.2 22.0 4.7e-97 325.2 22.0 3.2 2 2 0 2 2 2 1 ZIP Zinc transporter OAD_gamma PF04277.13 KFP19810.1 - 0.11 13.0 0.8 11 6.7 0.0 3.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GCV_H PF01597.19 KFP19811.1 - 3.4e-08 33.4 0.0 6.1e-08 32.6 0.0 1.4 2 0 0 2 2 2 1 Glycine cleavage H-protein Vinculin PF01044.19 KFP19812.1 - 2e-51 175.3 22.5 3e-32 111.9 7.8 3.5 2 1 0 3 3 3 3 Vinculin family WXG100 PF06013.12 KFP19812.1 - 0.086 13.1 5.4 0.066 13.5 1.2 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG WD40 PF00400.32 KFP19813.1 - 3.3e-40 135.3 28.2 0.0003 21.5 1.2 12.8 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19813.1 - 7.8e-05 22.9 4.4 3.1 8.1 0.1 6.6 5 3 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP19813.1 - 0.015 15.2 3.0 5.3 6.9 0.2 4.1 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A bHLH-MYC_N PF14215.6 KFP19813.1 - 0.036 14.4 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Nbas_N PF15492.6 KFP19813.1 - 0.041 13.2 1.0 0.77 9.0 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KFP19813.1 - 0.91 9.5 3.1 62 3.7 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat 7tm_3 PF00003.22 KFP19814.1 - 4.1e-60 203.5 15.0 5.6e-60 203.0 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GBR2_CC PF18455.1 KFP19814.1 - 2.5e-26 91.5 3.3 5e-26 90.5 3.3 1.5 1 0 0 1 1 1 1 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain UPF0242 PF06785.11 KFP19814.1 - 0.027 14.6 1.4 0.039 14.1 0.7 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HOOK PF05622.12 KFP19814.1 - 0.031 12.4 5.8 0.042 12.0 5.8 1.1 1 0 0 1 1 1 0 HOOK protein Cation_ATPase_C PF00689.21 KFP19814.1 - 0.047 13.4 17.3 0.28 10.9 1.7 2.9 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus GWT1 PF06423.12 KFP19814.1 - 0.069 13.3 4.6 0.47 10.6 0.8 2.7 2 1 1 3 3 3 0 GWT1 GAPT PF11770.8 KFP19814.1 - 0.07 13.0 4.0 0.35 10.7 0.4 2.5 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) E2F_CC-MB PF16421.5 KFP19814.1 - 0.39 11.1 3.3 0.79 10.1 3.3 1.5 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain TMEM52 PF14979.6 KFP19814.1 - 0.52 10.2 3.3 0.56 10.1 0.4 2.4 3 0 0 3 3 3 0 Transmembrane 52 Lectin_N PF03954.14 KFP19814.1 - 1.2 8.9 5.1 0.46 10.2 2.3 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 KFP19814.1 - 1.3 8.3 3.3 1.8 7.9 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0014 PF03649.13 KFP19814.1 - 9.3 5.5 10.9 2.4 7.4 1.2 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0014) RVT_1 PF00078.27 KFP19815.1 - 2.5e-17 63.1 0.0 4.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP19815.1 - 0.11 12.5 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Homeobox_KN PF05920.11 KFP19817.1 - 1.2e-15 57.1 0.4 1.2e-15 57.1 0.4 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KFP19817.1 - 7.8e-07 28.8 0.1 1.5e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain SDA1 PF05285.12 KFP19817.1 - 0.012 15.1 11.8 0.016 14.7 11.8 1.1 1 0 0 1 1 1 0 SDA1 Dicty_REP PF05086.12 KFP19817.1 - 0.039 12.0 0.6 0.053 11.5 0.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MRP-S32 PF10210.9 KFP19817.1 - 0.19 12.3 1.4 0.8 10.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 RRM_1 PF00076.22 KFP19818.1 - 1e-39 134.2 0.0 6.5e-20 70.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP19818.1 - 3.2e-06 27.2 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KFP19818.1 - 0.00063 19.3 0.0 0.5 10.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KFP19818.1 - 0.0089 15.7 0.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 KFP19818.1 - 0.041 14.0 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 MFS_1 PF07690.16 KFP19819.1 - 2.8e-23 82.4 18.9 2e-16 59.9 8.6 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP19819.1 - 2.8e-20 72.6 9.4 6.4e-17 61.5 2.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.6 KFP19819.1 - 4.5e-07 29.9 7.9 9.7e-07 28.9 7.9 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) MFS_3 PF05977.13 KFP19819.1 - 0.019 13.4 0.0 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Pentapeptide_3 PF13576.6 KFP19819.1 - 0.072 13.3 7.3 3.6 7.8 3.5 2.7 1 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KFP19819.1 - 0.12 12.1 0.2 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) zf-RING_9 PF13901.6 KFP19820.1 - 4.3e-68 229.4 8.3 7.5e-68 228.6 8.3 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon PH PF00169.29 KFP19820.1 - 1.9e-13 50.8 0.5 8.5e-10 39.1 0.0 2.9 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 KFP19820.1 - 0.12 12.1 0.3 1.3 8.8 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain TF_Zn_Ribbon PF08271.12 KFP19820.1 - 6.4 6.4 7.2 0.4 10.2 1.2 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding ALS2CR8 PF15299.6 KFP19821.1 - 1.2e-59 201.8 1.2 1.8e-59 201.3 1.2 1.2 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 WD40 PF00400.32 KFP19822.1 - 1.9e-33 113.9 29.3 2.1e-05 25.2 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19822.1 - 1.9e-05 24.8 4.7 0.0081 16.4 0.1 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KFP19822.1 - 0.00061 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAM117 PF15388.6 KFP19823.1 - 1e-123 412.8 12.8 1.5e-123 412.3 12.8 1.2 1 0 0 1 1 1 1 Protein Family FAM117 Pkinase PF00069.25 KFP19824.1 - 6.3e-33 114.3 0.0 1.2e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19824.1 - 1.3e-29 103.3 0.0 2.9e-29 102.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFP19824.1 - 1.3e-11 45.5 7.3 1.3e-11 45.5 7.3 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.23 KFP19824.1 - 0.0016 18.4 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP19824.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cadherin_C_2 PF16492.5 KFP19824.1 - 0.072 13.8 0.1 1.1 10.0 0.0 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Nop PF01798.18 KFP19825.1 - 7.4e-85 284.1 0.1 1.9e-84 282.7 0.1 1.7 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFP19825.1 - 7.9e-14 51.8 1.6 7.9e-14 51.8 1.6 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF2247 PF10004.9 KFP19825.1 - 0.014 15.2 1.0 0.15 11.8 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) RNA_polI_A34 PF08208.11 KFP19825.1 - 0.024 14.7 25.9 0.045 13.8 25.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 tRNA-synt_His PF13393.6 KFP19825.1 - 0.21 10.8 2.0 2.7 7.2 1.8 2.4 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Rad60-SLD PF11976.8 KFP19826.1 - 7.1e-22 77.0 0.2 8.5e-22 76.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFP19826.1 - 2e-18 65.9 0.7 2.4e-18 65.7 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family Frizzled PF01534.17 KFP19828.1 - 6.1e-139 462.6 20.2 7.4e-139 462.3 20.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KFP19828.1 - 1.4e-33 115.8 3.6 1.4e-33 115.8 3.6 1.7 2 0 0 2 2 2 1 Fz domain RCC1 PF00415.18 KFP19829.1 - 2.6e-40 136.8 15.6 3.3e-11 43.6 0.2 7.2 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP19829.1 - 5.4e-26 89.8 25.9 9.1e-07 28.5 1.3 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.20 KFP19829.1 - 9.7e-26 88.1 29.7 2.6e-05 23.8 2.7 9.4 8 1 0 8 8 8 7 MORN repeat VPS9 PF02204.18 KFP19829.1 - 7.1e-24 84.0 0.1 6.7e-23 80.9 0.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.20 KFP19829.1 - 5.9e-06 26.7 1.2 1.2e-05 25.6 1.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KFP19829.1 - 0.002 18.6 0.0 0.0074 16.8 0.0 2.0 1 0 0 1 1 1 1 PH domain TMEM237 PF15383.6 KFP19831.1 - 1.6e-103 345.2 0.5 2.2e-103 344.7 0.5 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 CAF20 PF17052.5 KFP19831.1 - 0.012 15.8 2.6 0.019 15.1 2.6 1.3 1 0 0 1 1 1 0 Cap associated factor Pkinase PF00069.25 KFP19832.1 - 2.6e-37 128.6 0.0 2.8e-36 125.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19832.1 - 7.1e-29 100.9 0.0 3.8e-25 88.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP19832.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ASXH PF13919.6 KFP19832.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Asx homology domain DED PF01335.21 KFP19833.1 - 2.8e-42 142.9 8.6 1.2e-21 76.8 1.2 3.0 2 1 0 2 2 2 2 Death effector domain Peptidase_C14 PF00656.22 KFP19833.1 - 9.4e-39 133.8 0.6 2e-38 132.8 0.1 1.8 2 0 0 2 2 2 1 Caspase domain PYRIN PF02758.16 KFP19833.1 - 0.0015 18.6 0.1 0.0085 16.2 0.2 2.3 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain Peptidase_C14 PF00656.22 KFP19834.1 - 3.8e-46 158.1 0.0 6.4e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DED PF01335.21 KFP19834.1 - 5.6e-40 135.5 17.7 4.4e-21 75.0 2.2 2.8 3 0 0 3 3 3 2 Death effector domain Lact-deh-memb PF09330.11 KFP19834.1 - 0.047 13.0 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding NDUF_B12 PF08122.12 KFP19835.1 - 2e-23 82.2 0.8 3.1e-23 81.6 0.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ORC2 PF04084.14 KFP19837.1 - 8.6e-106 353.6 0.8 1.4e-105 352.9 0.8 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NIF3 PF01784.18 KFP19838.1 - 1.2e-81 273.9 0.0 1.9e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Pro_isomerase PF00160.21 KFP19839.1 - 9e-53 178.8 0.0 1e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 KFP19840.1 - 1.9e-53 181.5 0.1 2.5e-53 181.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19840.1 - 7.6e-25 87.7 0.1 6.6e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP19840.1 - 0.17 11.8 0.4 15 5.4 0.0 2.7 3 1 0 3 3 3 0 Phosphotransferase enzyme family W2 PF02020.18 KFP19841.1 - 2.6e-08 33.9 3.6 5e-06 26.6 0.6 3.1 3 0 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon Ald_Xan_dh_C2 PF02738.18 KFP19843.1 - 1e-191 638.2 0.0 1.4e-191 637.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFP19843.1 - 5.3e-39 133.7 0.0 1.2e-38 132.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KFP19843.1 - 2.7e-34 117.9 1.3 6.1e-34 116.7 1.3 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KFP19843.1 - 1.2e-30 105.4 1.1 3e-30 104.1 1.1 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KFP19843.1 - 4e-27 94.4 0.1 6.5e-26 90.5 0.0 2.8 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 KFP19843.1 - 0.00027 20.8 2.4 0.00027 20.8 2.4 3.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Shugoshin_C PF07557.11 KFP19844.1 - 1.4e-10 40.8 1.5 2.3e-10 40.1 1.5 1.4 1 0 0 1 1 1 1 Shugoshin C terminus BTB_2 PF02214.22 KFP19845.1 - 3.9e-12 46.3 0.0 2e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFP19845.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ashwin PF15323.6 KFP19845.1 - 0.014 15.4 2.1 0.02 15.0 2.1 1.2 1 0 0 1 1 1 0 Developmental protein MBA1 PF07961.11 KFP19846.1 - 0.041 12.9 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 MBA1-like protein Cupin_8 PF13621.6 KFP19847.1 - 7.6e-40 137.2 0.0 9.2e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP19847.1 - 5.2e-13 49.2 0.0 7.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFP19847.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase UPF0565 PF10561.9 KFP19848.1 - 6e-97 324.5 0.7 6.9e-97 324.3 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 CUT PF02376.15 KFP19850.1 - 2.2e-48 162.3 4.3 1.7e-24 85.7 0.1 3.3 4 0 0 4 4 4 2 CUT domain CUTL PF16557.5 KFP19850.1 - 1.6e-42 143.6 1.5 1.6e-42 143.6 1.5 3.2 4 0 0 4 4 4 1 CUT1-like DNA-binding domain of SATB ULD PF16534.5 KFP19850.1 - 1.8e-36 124.5 0.0 4.6e-36 123.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like oligomerisation domain of SATB Homeodomain PF00046.29 KFP19850.1 - 1.9e-06 27.6 0.0 5.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain PI-PLC-X PF00388.19 KFP19852.1 - 5.1e-52 175.3 0.1 1.1e-51 174.2 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP19852.1 - 6.3e-41 139.3 0.4 1.7e-40 138.0 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 KFP19852.1 - 3.1e-19 69.8 0.0 9.7e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 KFP19852.1 - 5e-18 65.3 0.0 2.4e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 KFP19852.1 - 1e-14 54.7 0.0 2.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 KFP19852.1 - 9.2e-08 32.0 0.1 3.5e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.6 KFP19852.1 - 0.0074 16.7 2.1 0.028 14.9 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair Mcp5_PH PF12814.7 KFP19852.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KFP19852.1 - 0.094 13.2 0.2 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 PH domain Raftlin PF15250.6 KFP19853.1 - 5.2e-185 615.7 0.1 8e-184 611.8 0.1 1.9 1 1 0 1 1 1 1 Raftlin Mob1_phocein PF03637.17 KFP19854.1 - 9.5e-35 120.1 1.0 1.4e-34 119.6 0.8 1.3 1 1 0 1 1 1 1 Mob1/phocein family Cpn10 PF00166.21 KFP19855.1 - 2.2e-29 101.4 0.1 2.4e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 KFP19856.1 - 3e-86 290.0 16.1 8.1e-86 288.6 16.1 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF126 PF01989.16 KFP19856.1 - 0.092 12.6 0.1 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 Aconitase X swivel domain Polyketide_cyc PF03364.20 KFP19857.1 - 1.1e-23 83.9 0.0 1.3e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFP19857.1 - 0.0052 17.1 0.0 0.007 16.6 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SF3b1 PF08920.10 KFP19858.1 - 4.3e-47 159.5 6.5 4.3e-47 159.5 6.5 4.7 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KFP19858.1 - 6.3e-08 32.9 5.0 0.031 14.6 0.0 7.1 5 2 4 9 9 9 3 HEAT repeats HEAT PF02985.22 KFP19858.1 - 1.2e-07 31.3 7.0 1.2 9.5 0.1 8.7 10 0 0 10 10 9 1 HEAT repeat HEAT_EZ PF13513.6 KFP19858.1 - 2.2e-07 31.2 3.1 0.52 10.9 0.0 7.0 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFP19858.1 - 1.9e-05 25.2 0.6 3 8.5 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP19858.1 - 0.0014 18.7 8.3 5.6 7.0 0.0 6.3 7 1 1 9 9 9 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KFP19858.1 - 0.0018 17.9 1.0 3.6 7.1 0.1 3.3 3 0 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 KFP19858.1 - 0.0042 17.0 2.2 4.2 7.3 0.1 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) UME PF08064.13 KFP19858.1 - 0.0057 16.5 0.1 6.1 6.8 0.0 5.2 6 1 1 7 7 7 1 UME (NUC010) domain Adaptin_N PF01602.20 KFP19858.1 - 0.0083 14.7 1.8 0.13 10.7 1.8 2.8 1 1 0 1 1 1 1 Adaptin N terminal region NUC173 PF08161.12 KFP19858.1 - 0.012 15.2 0.2 2.5 7.7 0.0 4.1 4 1 0 4 4 4 0 NUC173 domain DRIM PF07539.12 KFP19858.1 - 0.024 12.9 0.1 5.2 5.2 0.0 3.3 3 1 0 4 4 4 0 Down-regulated in metastasis DNA_pol_phi PF04931.13 KFP19858.1 - 0.026 12.6 0.0 4.3 5.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi UNC45-central PF11701.8 KFP19858.1 - 0.027 14.4 0.5 0.097 12.6 0.0 2.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central PGAP1 PF07819.13 KFP19859.1 - 3.8e-77 259.1 0.0 7.1e-77 258.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KFP19859.1 - 0.00056 19.8 0.0 0.00096 19.1 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KFP19859.1 - 0.0021 18.7 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KFP19859.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KFP19859.1 - 0.0068 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP19859.1 - 0.031 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP19859.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KFP19859.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF4720 PF15846.5 KFP19860.1 - 3.7e-48 161.3 0.1 4.3e-48 161.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4720) HECT PF00632.25 KFP19861.1 - 2e-104 349.4 0.0 3.1e-104 348.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW_N PF16562.5 KFP19861.1 - 1.8e-59 198.8 0.0 3.2e-59 198.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 HECW1_helix PF18436.1 KFP19861.1 - 1.2e-36 124.6 3.1 4.7e-35 119.5 1.0 3.1 3 0 0 3 3 3 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 WW PF00397.26 KFP19861.1 - 2e-17 63.0 0.4 1.8e-09 37.5 0.3 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KFP19861.1 - 6.9e-13 48.8 0.0 2e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain Pkinase PF00069.25 KFP19862.1 - 2.8e-69 233.4 0.0 3.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19862.1 - 8.7e-36 123.5 0.0 1.1e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19862.1 - 0.0025 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP19862.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFP19862.1 - 0.039 13.9 0.1 0.098 12.6 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP19862.1 - 0.049 13.0 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BIR PF00653.21 KFP19865.1 - 1e-21 77.3 3.1 1.9e-21 76.5 3.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KFP19865.1 - 0.0066 16.5 0.7 0.01 15.9 0.7 1.4 1 0 0 1 1 1 1 C3HC zinc finger-like Zip PF02535.22 KFP19866.1 - 7.5e-103 344.2 18.1 2.3e-66 224.3 11.9 5.0 2 2 3 5 5 5 2 ZIP Zinc transporter Dicty_REP PF05086.12 KFP19866.1 - 4.7 5.1 9.1 8.4 4.2 9.1 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ArgoMid PF16487.5 KFP19872.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Mid domain of argonaute Kazal_2 PF07648.15 KFP19877.1 - 7e-19 67.7 33.6 1.2e-10 41.3 7.8 4.6 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP19877.1 - 2.3e-13 49.9 19.7 4.5e-09 36.2 5.8 4.7 3 2 2 5 5 5 2 Kazal-type serine protease inhibitor domain EGF_2 PF07974.13 KFP19877.1 - 0.0012 19.2 9.0 0.0012 19.2 9.0 5.2 3 2 2 5 5 5 2 EGF-like domain EphA2_TM PF14575.6 KFP19877.1 - 0.52 11.2 2.0 0.61 11.0 0.3 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 KFP19877.1 - 1.3 10.0 2.9 2.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PTRF_SDPR PF15237.6 KFP19878.1 - 6.3e-55 186.5 17.3 6.3e-55 186.5 17.3 2.2 2 1 0 2 2 2 1 PTRF/SDPR family Tash_PEST PF07708.11 KFP19878.1 - 0.14 12.4 0.3 0.14 12.4 0.3 3.0 4 0 0 4 4 4 0 Tash protein PEST motif DUF4695 PF15766.5 KFP19878.1 - 0.14 12.4 11.9 2 8.7 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4695) YlbD_coat PF14071.6 KFP19878.1 - 0.27 11.5 10.5 0.057 13.7 6.4 1.9 1 1 1 2 2 2 0 Putative coat protein TMEM192 PF14802.6 KFP19878.1 - 1.3 8.0 4.7 0.23 10.5 0.7 1.6 2 0 0 2 2 2 0 TMEM192 family Pkinase PF00069.25 KFP19879.1 - 1.5e-56 191.7 0.0 1.7e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP19879.1 - 1.4e-33 116.3 0.0 1.7e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19879.1 - 6.2e-10 38.9 0.0 3.2e-09 36.5 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP19879.1 - 9e-06 24.7 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP19879.1 - 1.8e-05 24.2 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP19879.1 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFP19879.1 - 0.038 13.6 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KFP19879.1 - 0.061 13.2 0.2 0.18 11.7 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP19879.1 - 0.22 10.4 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Myosin_head PF00063.21 KFP19881.1 - 1.1e-267 889.7 5.4 1.5e-267 889.3 5.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFP19881.1 - 1.5e-43 148.7 8.4 7.4e-43 146.4 1.6 3.1 3 0 0 3 3 3 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFP19881.1 - 2.1e-06 27.0 24.4 0.00033 20.2 0.9 6.1 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP19881.1 - 0.0073 16.7 0.1 0.028 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP19881.1 - 0.03 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KFP19881.1 - 0.039 13.5 0.9 2 7.9 0.0 2.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 KFP19881.1 - 0.059 13.1 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Chorismate_bind PF00425.18 KFP19881.1 - 0.1 12.2 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 chorismate binding enzyme DUF4441 PF14536.6 KFP19881.1 - 3.4 7.9 10.2 2.9 8.1 1.3 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) RVT_1 PF00078.27 KFP19882.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NEMP PF10225.9 KFP19885.1 - 2.4e-81 273.1 7.2 3.3e-81 272.6 7.2 1.2 1 0 0 1 1 1 1 NEMP family Kringle PF00051.18 KFP19885.1 - 0.063 13.6 2.4 2 8.8 0.0 2.8 2 1 0 2 2 2 0 Kringle domain DUF5381 PF17353.2 KFP19885.1 - 2.8 7.7 9.0 0.18 11.5 3.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5381) MFS_1_like PF12832.7 KFP19886.1 - 1.1e-92 310.8 11.6 1.5e-92 310.4 11.6 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KFP19886.1 - 6.2e-30 104.3 25.7 9e-17 61.0 11.7 3.5 2 2 2 4 4 4 4 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KFP19886.1 - 1e-07 31.3 7.0 1e-07 31.3 7.0 3.6 3 1 0 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.19 KFP19886.1 - 1.4e-06 27.3 18.5 0.0016 17.3 3.8 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_2 PF13347.6 KFP19886.1 - 0.00013 20.6 17.0 0.031 12.8 0.0 3.6 2 1 1 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.13 KFP19886.1 - 0.00079 17.9 2.0 0.00096 17.7 0.7 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF5316 PF17247.2 KFP19886.1 - 0.089 12.8 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5316) OppC_N PF12911.7 KFP19886.1 - 3.4 7.7 12.1 4.4 7.4 0.0 3.9 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ECH_2 PF16113.5 KFP19887.1 - 7.6e-139 462.9 0.0 9.6e-139 462.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFP19887.1 - 1.7e-33 116.0 0.0 7.6e-31 107.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Thioredox_DsbH PF03190.15 KFP19887.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 TGFb_propeptide PF00688.18 KFP19888.1 - 7e-34 117.7 0.0 8.7e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP19888.1 - 5.6e-26 91.5 1.6 1.8e-25 89.9 1.6 1.9 1 0 0 1 1 1 1 Transforming growth factor beta like domain LydB PF16084.5 KFP19888.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 LydA-holin antagonist Cys_knot PF00007.22 KFP19888.1 - 0.69 10.2 5.0 0.15 12.4 1.5 1.8 2 0 0 2 2 2 0 Cystine-knot domain DNA_mis_repair PF01119.19 KFP19889.1 - 1.3e-24 86.2 0.0 3.5e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFP19889.1 - 9.4e-12 44.9 0.2 2.2e-11 43.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.19 KFP19889.1 - 6.3e-10 39.3 2.4 6.3e-10 39.3 2.4 2.4 4 0 0 4 4 4 1 HMG (high mobility group) box HATPase_c PF02518.26 KFP19889.1 - 4.9e-09 36.7 0.2 1e-08 35.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box_2 PF09011.10 KFP19889.1 - 1.5e-08 35.1 1.6 3.9e-08 33.8 1.6 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KFP19889.1 - 0.0089 16.0 1.2 0.025 14.6 1.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 KFP19889.1 - 0.064 13.2 0.1 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 CHDNT (NUC034) domain ORMDL PF04061.14 KFP19890.1 - 5e-54 181.8 1.8 5.6e-54 181.6 1.8 1.0 1 0 0 1 1 1 1 ORMDL family Peptidase_M22 PF00814.25 KFP19891.1 - 3.1e-56 191.0 1.0 3.6e-56 190.8 1.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Asn_synthase PF00733.21 KFP19892.1 - 2.2e-18 67.0 0.0 1.1e-08 35.2 0.0 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFP19892.1 - 2.6e-06 27.4 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFP19892.1 - 0.0021 18.3 0.0 0.017 15.3 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.20 KFP19892.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Kelch_3 PF13415.6 KFP19892.1 - 0.091 13.1 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain QueC PF06508.13 KFP19892.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC FPN1 PF06963.12 KFP19893.1 - 3.7e-185 615.6 14.0 4.2e-185 615.4 14.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.16 KFP19893.1 - 4.4e-07 29.1 31.0 4.9e-06 25.7 2.4 3.6 3 1 1 4 4 4 3 Major Facilitator Superfamily Vezatin PF12632.7 KFP19893.1 - 0.53 9.6 2.7 0.84 9.0 2.7 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Presenilin PF01080.17 KFP19893.1 - 0.65 8.7 7.1 1.3 7.7 7.1 1.6 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 KFP19894.1 - 1.1e-12 48.2 16.8 0.00037 21.2 0.2 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19894.1 - 3e-05 24.2 0.1 2.2 8.6 0.0 5.0 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain COLFI PF01410.18 KFP19895.1 - 3.7e-54 183.5 0.1 4.1e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain COLFI PF01410.18 KFP19896.1 - 1.4e-54 184.9 0.0 1.5e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SNARE PF05739.19 KFP19896.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 SNARE domain PID PF00640.23 KFP19901.1 - 6.7e-31 107.2 0.3 9.9e-31 106.6 0.3 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP19901.1 - 2.1e-12 47.3 0.2 3.7e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP19901.1 - 1.9e-05 24.6 0.1 2.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Ax_dynein_light PF10211.9 KFP19901.1 - 0.002 18.1 0.4 0.0032 17.4 0.4 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain TSC22 PF01166.18 KFP19901.1 - 0.0026 18.0 1.7 0.0081 16.5 1.7 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_2 PF07716.15 KFP19901.1 - 0.0033 17.5 4.7 0.0075 16.3 4.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.15 KFP19901.1 - 0.0041 16.9 4.7 0.0072 16.1 4.7 1.3 1 0 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFP19901.1 - 0.0095 16.4 2.1 0.02 15.3 2.1 1.5 1 0 0 1 1 1 1 Cell division protein ZapB bZIP_1 PF00170.21 KFP19901.1 - 0.011 15.8 2.0 0.022 14.9 2.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor KASH_CCD PF14662.6 KFP19901.1 - 0.013 15.4 0.6 0.023 14.5 0.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Pox_A_type_inc PF04508.12 KFP19901.1 - 0.016 15.1 2.9 0.097 12.6 0.2 2.6 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat HAP1_N PF04849.13 KFP19901.1 - 0.021 14.0 0.4 0.029 13.6 0.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF4337 PF14235.6 KFP19901.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2004 PF09406.10 KFP19901.1 - 0.023 15.0 0.1 0.098 13.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2004) Cnn_1N PF07989.11 KFP19901.1 - 0.025 14.7 0.6 0.052 13.7 0.6 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Spc24 PF08286.11 KFP19901.1 - 0.046 13.9 0.5 0.096 12.9 0.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 KFP19901.1 - 0.06 13.4 2.8 0.11 12.5 2.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 KFP19901.1 - 0.063 13.9 1.9 0.13 12.9 1.9 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Herpes_UL6 PF01763.16 KFP19901.1 - 0.064 11.8 0.2 0.093 11.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like GIT_CC PF16559.5 KFP19901.1 - 0.079 12.8 0.5 0.079 12.8 0.5 1.8 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 KFP19901.1 - 0.093 13.3 1.7 0.17 12.4 1.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KFP19901.1 - 0.12 13.0 1.6 0.29 11.8 1.6 1.6 1 0 0 1 1 1 0 SlyX ATG16 PF08614.11 KFP19901.1 - 0.22 11.7 2.7 0.38 11.0 2.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) 7tm_2 PF00002.24 KFP19905.1 - 1.5e-80 270.1 19.3 1.9e-80 269.7 19.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP19905.1 - 1.6e-18 66.7 8.0 3.1e-18 65.8 8.0 1.5 1 0 0 1 1 1 1 Hormone receptor domain DUF4034 PF13226.6 KFP19905.1 - 0.082 12.3 0.4 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) DUF2070 PF09843.9 KFP19905.1 - 2 6.6 9.0 2.9 6.1 9.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0560 PF10577.9 KFP19909.1 - 3e-146 489.1 10.7 6.7e-98 329.2 3.2 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0560 Prominin PF05478.11 KFP19909.1 - 0.00056 18.0 0.1 0.00092 17.3 0.1 1.2 1 0 0 1 1 1 1 Prominin Orthoreo_P10 PF07204.11 KFP19909.1 - 0.089 12.8 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Integrin_alpha2 PF08441.12 KFP19910.1 - 1.5e-121 406.5 0.0 1.9e-121 406.3 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KFP19910.1 - 6.2e-29 99.8 19.4 1.3e-08 34.8 0.2 4.6 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.6 KFP19910.1 - 4.6e-15 56.0 9.7 1.4e-05 25.6 0.7 4.3 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 KFP19910.1 - 7.9e-05 22.4 0.7 0.00017 21.3 0.7 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region LYRIC PF15686.5 KFP19910.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family DFRP_C PF16543.5 KFP19911.1 - 1.6e-22 79.8 2.1 1.6e-22 79.8 2.1 3.8 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KFP19911.1 - 7.4e-09 35.2 6.1 9.7e-07 28.5 1.2 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KFP19911.1 - 4.5e-07 30.6 11.8 2e-05 25.3 3.6 3.2 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFP19911.1 - 1.2e-06 28.4 6.1 1.2e-06 28.4 6.1 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KFP19911.1 - 2.6e-06 27.2 2.6 2.7e-06 27.1 0.9 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP19911.1 - 0.0086 16.5 12.4 0.056 13.9 3.9 3.0 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP19911.1 - 0.03 14.5 8.9 0.26 11.5 3.8 3.1 1 1 1 2 2 2 0 Zinc-finger containing family TLV_coat PF00429.19 KFP19912.1 - 0.0036 16.1 0.3 0.0036 16.1 0.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Proteasome PF00227.26 KFP19913.1 - 1.5e-32 112.6 0.0 1.7e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 KFP19913.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain zf-C2H2_4 PF13894.6 KFP19914.1 - 5e-12 45.6 51.8 0.023 15.5 0.6 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 KFP19914.1 - 3.2e-05 24.1 40.8 0.022 15.0 0.4 5.3 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFP19914.1 - 0.00086 19.6 56.1 0.2 12.2 0.2 7.6 7 1 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP19914.1 - 0.0077 16.6 5.3 0.055 13.9 0.3 6.8 9 0 0 9 9 7 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP19914.1 - 0.069 13.5 31.0 0.15 12.4 0.5 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KFP19914.1 - 0.14 12.1 0.1 0.14 12.1 0.1 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYVE PF01363.21 KFP19914.1 - 0.19 11.9 0.0 0.19 11.9 0.0 4.8 3 1 1 4 4 3 0 FYVE zinc finger zf-C2H2_11 PF16622.5 KFP19914.1 - 0.54 10.1 0.0 0.54 10.1 0.0 4.4 5 0 0 5 5 5 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KFP19914.1 - 0.76 10.5 19.3 2.8 8.7 0.1 4.6 2 1 2 4 4 4 0 FOXP coiled-coil domain Rubredoxin PF00301.20 KFP19914.1 - 0.77 9.8 0.0 0.77 9.8 0.0 5.9 7 0 0 7 7 7 0 Rubredoxin zinc_ribbon_15 PF17032.5 KFP19914.1 - 2.4 9.0 22.8 0.35 11.6 0.4 4.5 3 2 2 5 5 5 0 zinc-ribbon family zinc_ribbon_5 PF13719.6 KFP19914.1 - 9.2 6.1 10.5 4.6 7.1 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain SBP56 PF05694.11 KFP19915.1 - 3.5e-220 731.5 0.0 4.1e-220 731.3 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFP19915.1 - 0.00032 20.1 0.0 0.0018 17.6 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.11 KFP19916.1 - 2.3e-185 616.8 0.0 2.6e-185 616.6 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFP19916.1 - 0.00034 20.0 0.0 0.00091 18.6 0.0 1.6 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller RFX_DNA_binding PF02257.15 KFP19917.1 - 6.5e-27 94.0 0.1 8.2e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 RFX DNA-binding domain RFX5_N PF18326.1 KFP19917.1 - 1.2e-15 57.0 2.9 1.7e-15 56.5 2.9 1.2 1 0 0 1 1 1 1 RFX5 N-terminal domain Pox_D5 PF03288.16 KFP19917.1 - 0.00051 20.5 0.0 0.00083 19.8 0.0 1.4 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 KFP19917.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PI3_PI4_kinase PF00454.27 KFP19918.1 - 6.3e-34 117.9 0.5 3.1e-22 79.6 0.2 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KFP19918.1 - 0.014 14.8 0.1 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) UIM PF02809.20 KFP19919.1 - 2.2e-08 33.5 6.0 0.00011 21.9 0.4 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA_2 PF13519.6 KFP19919.1 - 4.2e-06 27.4 0.4 3.8e-05 24.3 0.0 2.7 3 1 1 4 4 4 1 von Willebrand factor type A domain RAP80_UIM PF18282.1 KFP19919.1 - 0.014 15.2 9.5 0.024 14.4 3.0 2.6 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif RhlB PF12300.8 KFP19919.1 - 0.071 13.2 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB LRR_6 PF13516.6 KFP19920.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat 7tm_4 PF13853.6 KFP19921.1 - 8.2e-19 68.4 3.8 9.6e-19 68.2 3.8 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19921.1 - 0.09 12.1 5.0 0.11 11.8 5.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP19922.1 - 6.5e-50 170.4 9.2 7.5e-50 170.2 9.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP19922.1 - 3.3e-31 108.6 12.1 4.4e-31 108.2 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP19922.1 - 0.0061 16.0 11.8 0.0097 15.3 11.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ELMO_CED12 PF04727.13 KFP19923.1 - 4.3e-49 167.0 0.3 5.6e-49 166.6 0.3 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family zf-RING_2 PF13639.6 KFP19925.1 - 1.8e-12 47.4 6.6 3e-12 46.7 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP19925.1 - 2.5e-10 39.9 1.5 5.9e-10 38.7 1.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP19925.1 - 2.6e-08 33.5 6.4 4.4e-08 32.8 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP19925.1 - 1.3e-07 31.4 4.7 2.1e-07 30.7 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP19925.1 - 3e-07 30.3 3.5 4.6e-07 29.7 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP19925.1 - 1.1e-06 28.3 4.4 2.1e-06 27.5 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP19925.1 - 2.1e-06 27.9 8.1 5.5e-06 26.6 8.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP19925.1 - 9.6e-06 25.4 3.6 1.5e-05 24.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP19925.1 - 1.2e-05 25.2 4.7 2.2e-05 24.4 4.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger PspB PF06667.12 KFP19925.1 - 0.0015 18.5 0.2 0.0026 17.8 0.2 1.3 1 0 0 1 1 1 1 Phage shock protein B Ninjurin PF04923.12 KFP19925.1 - 0.0017 18.3 0.3 0.0034 17.3 0.3 1.4 1 0 0 1 1 1 1 Ninjurin CrgA PF06781.12 KFP19925.1 - 0.0021 18.1 0.2 0.0041 17.2 0.2 1.5 1 0 0 1 1 1 1 Cell division protein CrgA zf-ANAPC11 PF12861.7 KFP19925.1 - 0.0065 16.5 2.3 0.012 15.7 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger BatD PF13584.6 KFP19925.1 - 0.023 13.6 0.1 0.033 13.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance zf-C3H2C3 PF17122.5 KFP19925.1 - 0.034 14.2 2.7 0.081 13.0 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 KFP19925.1 - 0.052 13.2 5.4 0.27 10.9 5.5 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Pox_A31 PF05771.11 KFP19925.1 - 0.095 12.7 0.3 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A31 protein PHD PF00628.29 KFP19925.1 - 0.15 12.0 4.3 0.26 11.2 4.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KFP19925.1 - 0.37 10.9 4.4 0.74 10.0 4.4 1.5 1 0 0 1 1 1 0 RING-variant domain NOA36 PF06524.12 KFP19929.1 - 7.6e-167 554.2 44.9 9.3e-167 553.9 44.9 1.0 1 0 0 1 1 1 1 NOA36 protein IL15 PF02372.15 KFP19930.1 - 1.1e-41 142.1 11.0 1.4e-41 141.6 11.0 1.2 1 0 0 1 1 1 1 Interleukin 15 DUF4941 PF16299.5 KFP19930.1 - 0.08 12.2 0.1 0.08 12.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4941) PH PF00169.29 KFP19933.1 - 5.3e-19 68.7 3.3 1.3e-18 67.4 0.1 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KFP19933.1 - 1.7e-05 25.1 0.3 0.00011 22.5 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFP19933.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 KFP19933.1 - 0.11 12.7 0.3 0.3 11.2 0.3 1.7 1 1 0 1 1 1 0 PH domain Phage_TAC_5 PF08890.11 KFP19933.1 - 0.22 11.5 0.1 0.64 10.0 0.0 1.7 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC PH_2 PF08458.10 KFP19933.1 - 0.23 11.9 0.0 0.43 11.0 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region GSDH PF07995.11 KFP19935.1 - 1.1e-19 71.0 0.0 1.6e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 KFP19935.1 - 1.9e-17 63.7 6.8 1.9e-17 63.7 6.8 2.4 2 0 0 2 2 2 1 Folate receptor family EGF_2 PF07974.13 KFP19935.1 - 0.00043 20.6 10.2 0.00043 20.6 10.2 3.5 2 1 1 3 3 3 2 EGF-like domain ANAPC10 PF03256.16 KFP19937.1 - 4.2e-83 277.5 0.0 5e-83 277.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFP19937.1 - 4.5e-05 23.6 0.0 5.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 KFP19937.1 - 0.0018 18.5 0.1 0.011 15.9 0.1 1.9 1 1 1 2 2 2 1 PITH domain ABC_tran PF00005.27 KFP19938.1 - 7.4e-38 130.2 0.0 1.5e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KFP19938.1 - 1.5e-14 53.5 7.2 4.2e-14 52.1 7.2 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFP19938.1 - 4.2e-11 42.7 1.6 0.0021 17.5 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFP19938.1 - 9.5e-11 42.0 2.9 0.17 11.7 0.7 4.4 3 2 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 KFP19938.1 - 1.1e-07 31.3 1.6 1.1e-07 31.3 1.6 3.8 5 0 0 5 5 4 1 4Fe-4S binding domain AAA_16 PF13191.6 KFP19938.1 - 1.1e-05 25.8 0.0 0.027 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KFP19938.1 - 1.5e-05 24.9 0.0 0.22 11.2 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KFP19938.1 - 3.1e-05 24.4 0.0 0.05 14.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFP19938.1 - 4e-05 23.6 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 KFP19938.1 - 4.3e-05 23.4 0.9 4.3e-05 23.4 0.9 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_22 PF13401.6 KFP19938.1 - 4.9e-05 23.6 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFP19938.1 - 9.3e-05 22.1 0.4 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KFP19938.1 - 0.00054 19.9 0.4 0.091 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 KFP19938.1 - 0.0013 18.7 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KFP19938.1 - 0.0016 18.2 0.2 0.079 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFP19938.1 - 0.0019 18.7 2.7 0.061 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KFP19938.1 - 0.002 18.7 9.5 0.0057 17.2 1.0 3.2 2 2 2 4 4 4 2 4Fe-4S dicluster domain AAA_33 PF13671.6 KFP19938.1 - 0.0022 18.2 0.0 0.49 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFP19938.1 - 0.0022 17.8 0.2 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFP19938.1 - 0.0024 18.2 0.0 2.1 8.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase SRP54 PF00448.22 KFP19938.1 - 0.003 17.2 1.9 0.31 10.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 KFP19938.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 3.1 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KFP19938.1 - 0.0063 16.7 10.0 0.0063 16.7 10.0 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFP19938.1 - 0.0085 16.2 1.7 0.0085 16.2 1.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_28 PF13521.6 KFP19938.1 - 0.011 16.0 0.2 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_21 PF14697.6 KFP19938.1 - 0.011 15.8 13.3 0.031 14.4 12.9 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain TsaE PF02367.17 KFP19938.1 - 0.014 15.4 0.2 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_16 PF13484.6 KFP19938.1 - 0.028 15.4 0.9 0.028 15.4 0.9 2.9 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain AAA_18 PF13238.6 KFP19938.1 - 0.041 14.4 0.0 9.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KFP19938.1 - 0.079 12.2 0.1 4 6.6 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_5 PF07728.14 KFP19938.1 - 0.083 12.9 1.1 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KFP19938.1 - 0.085 12.9 0.7 19 5.4 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KFP19938.1 - 0.089 12.0 0.0 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.11 KFP19938.1 - 0.1 12.3 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 KFP19938.1 - 0.12 11.9 0.2 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KFP19938.1 - 0.13 11.2 0.1 8 5.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KFP19938.1 - 0.15 11.8 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SbcCD_C PF13558.6 KFP19938.1 - 0.21 11.9 0.1 14 6.0 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KFP19938.1 - 0.39 10.8 3.1 29 4.7 0.0 3.6 3 1 1 4 4 3 0 AAA domain Fer4_17 PF13534.6 KFP19938.1 - 0.92 10.1 9.1 0.09 13.3 0.7 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KFP19938.1 - 5.9 7.7 15.1 0.45 11.1 2.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain OTU PF02338.19 KFP19939.1 - 7.4e-14 52.3 0.0 1.5e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease SMN PF06003.12 KFP19939.1 - 0.0028 16.9 0.0 0.0028 16.9 0.0 3.4 3 0 0 3 3 3 1 Survival motor neuron protein (SMN) Peptidase_C65 PF10275.9 KFP19939.1 - 0.04 13.4 0.9 7.5 5.9 0.1 2.5 1 1 1 2 2 2 0 Peptidase C65 Otubain CPSF100_C PF13299.6 KFP19939.1 - 4.5 7.4 5.9 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MH2 PF03166.14 KFP19940.1 - 2e-75 253.1 1.3 2.8e-75 252.6 1.3 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KFP19940.1 - 2.2e-42 143.5 1.2 5.6e-42 142.1 1.2 1.7 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KFP19940.1 - 0.00023 21.0 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KFP19940.1 - 0.13 12.3 0.8 0.27 11.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) MeaB PF03308.16 KFP19941.1 - 1.7e-93 312.5 0.2 2.2e-93 312.1 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KFP19941.1 - 3.2e-05 24.2 1.3 0.00053 20.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 KFP19941.1 - 0.00033 20.5 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein cobW PF02492.19 KFP19941.1 - 0.00048 19.8 0.0 0.0029 17.2 0.0 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFP19941.1 - 0.0057 17.2 0.1 0.016 15.7 0.0 1.8 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 KFP19941.1 - 0.0095 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFP19941.1 - 0.012 15.7 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KFP19941.1 - 0.013 16.0 0.4 0.031 14.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain MnmE_helical PF12631.7 KFP19941.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.4 1 1 0 1 1 1 0 MnmE helical domain Mg_chelatase PF01078.21 KFP19941.1 - 0.025 14.0 0.2 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFP19941.1 - 0.043 14.2 0.2 0.18 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 KFP19941.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.6 KFP19941.1 - 0.069 13.3 0.3 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFP19941.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KFP19941.1 - 0.085 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFP19941.1 - 0.11 12.2 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 KFP19941.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 KFP19941.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP19941.1 - 0.14 12.7 0.1 0.43 11.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain zf-H2C2_5 PF13909.6 KFP19942.1 - 1.1e-14 53.9 52.4 0.00056 19.6 3.1 7.6 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP19942.1 - 2.4e-10 40.3 78.7 0.0015 18.9 0.2 9.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP19942.1 - 1.2e-08 35.0 72.0 0.00057 20.2 4.7 10.4 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP19942.1 - 0.00053 20.6 78.1 0.081 13.8 0.3 9.6 9 0 0 9 9 9 4 C2H2-type zinc finger SRP54_N PF02881.19 KFP19942.1 - 0.046 14.0 3.0 7.4 6.9 0.1 3.4 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain GAGA PF09237.11 KFP19942.1 - 0.96 9.3 0.0 0.96 9.3 0.0 4.2 5 0 0 5 5 5 0 GAGA factor zf-met PF12874.7 KFP19942.1 - 1.4 9.5 60.4 0.8 10.2 2.8 8.5 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_7 PF15269.6 KFP19942.1 - 6.4 6.9 44.8 0.17 12.0 1.2 7.6 5 2 3 8 8 8 0 Zinc-finger OrsD PF12013.8 KFP19942.1 - 9.6 6.7 30.4 8.1 6.9 7.6 5.7 4 1 1 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D LSM PF01423.22 KFP19945.1 - 8.3e-20 70.3 0.1 9.4e-20 70.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFP19945.1 - 4.1e-05 23.6 0.0 4.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KFP19945.1 - 0.027 14.6 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Reeler PF02014.16 KFP19946.1 - 8.4e-30 104.2 0.0 9.8e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Reeler domain SBF_like PF13593.6 KFP19947.1 - 8.8e-60 202.6 17.9 9.7e-60 202.5 17.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KFP19947.1 - 1.4e-16 60.8 12.5 1.4e-16 60.8 12.5 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family Oxidored_q4 PF00507.19 KFP19947.1 - 1.2 9.3 8.7 0.13 12.5 2.4 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Phtf-FEM1B_bdg PF12129.8 KFP19947.1 - 1.7 8.5 6.2 1.8 8.4 0.3 2.5 2 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor DUF373 PF04123.13 KFP19947.1 - 6.1 6.2 8.8 92 2.3 9.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Pou PF00157.17 KFP19948.1 - 8.5e-30 102.5 0.0 1.1e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain HTH_31 PF13560.6 KFP19948.1 - 0.0057 17.0 0.0 0.0095 16.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_12 PF13424.6 KFP19949.1 - 2.5e-13 50.1 14.4 0.00028 21.1 0.0 5.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFP19949.1 - 1.4e-09 37.3 10.8 7.5e-05 22.4 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP19949.1 - 7.9e-08 32.0 7.7 5.5e-06 26.0 0.1 3.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 KFP19949.1 - 6.1e-07 29.2 13.3 0.0001 22.2 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP19949.1 - 7.2e-06 25.7 17.2 0.021 14.9 0.2 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP19949.1 - 5.1e-05 23.0 3.2 0.3 11.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP19949.1 - 9.6e-05 22.1 2.2 0.042 13.7 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19949.1 - 0.0016 19.1 5.3 5.5 8.1 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP19949.1 - 0.0019 17.8 3.8 0.12 12.0 0.6 4.1 4 0 0 4 4 4 1 TPR repeat SHNi-TPR PF10516.9 KFP19949.1 - 0.0042 16.5 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR Aminotran_3 PF00202.21 KFP19949.1 - 0.015 14.0 0.4 0.044 12.4 0.1 1.7 1 1 1 2 2 2 0 Aminotransferase class-III Lipoprotein_3 PF00938.17 KFP19949.1 - 0.037 14.2 0.7 7 6.9 0.2 2.6 2 0 0 2 2 2 0 Lipoprotein FANC_SAP PF18081.1 KFP19949.1 - 0.057 13.6 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain ANAPC3 PF12895.7 KFP19949.1 - 0.12 12.7 11.4 0.52 10.6 0.2 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFP19949.1 - 0.17 12.4 6.9 5.1 7.7 0.3 4.1 2 1 4 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KFP19949.1 - 0.19 11.4 0.1 0.19 11.4 0.1 3.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KFP19949.1 - 0.28 11.6 8.0 96 3.7 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFP19949.1 - 0.41 11.0 9.8 11 6.4 0.1 4.9 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP19949.1 - 0.98 10.2 8.7 36 5.3 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat 7tm_1 PF00001.21 KFP19951.1 - 1.5e-35 122.8 9.3 1.5e-35 122.8 9.3 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KFP19951.1 - 2.2e-05 23.9 12.4 4.8e-05 22.8 12.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KFP19951.1 - 0.0029 17.0 15.1 0.083 12.2 13.7 3.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP19951.1 - 0.0076 16.0 2.5 0.012 15.4 2.5 1.6 1 1 0 1 1 1 1 Olfactory receptor DUF4462 PF14692.6 KFP19952.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Solute_trans_a PF03619.16 KFP19953.1 - 2.1e-101 338.9 19.7 2.5e-101 338.7 19.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrmA PF06325.13 KFP19954.1 - 2.1e-10 40.5 0.0 7.9e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_2 PF07719.17 KFP19954.1 - 5.7e-08 32.3 1.2 0.0016 18.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Methyltransf_25 PF13649.6 KFP19954.1 - 6e-06 26.9 0.0 1.6e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFP19954.1 - 1.1e-05 25.4 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_1 PF00515.28 KFP19954.1 - 5.7e-05 22.8 1.9 0.16 11.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP19954.1 - 0.00011 22.7 0.6 0.25 12.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat MTS PF05175.14 KFP19954.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFP19954.1 - 0.0027 17.6 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP19954.1 - 0.009 16.6 0.0 0.024 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFP19954.1 - 0.009 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPR_11 PF13414.6 KFP19954.1 - 0.012 15.3 0.0 2.6 7.8 0.0 2.9 2 0 0 2 2 2 0 TPR repeat Methyltransf_16 PF10294.9 KFP19954.1 - 0.012 15.3 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase DREV PF05219.12 KFP19954.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Met_10 PF02475.16 KFP19954.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein BAR_3 PF16746.5 KFP19955.1 - 1.4e-65 221.4 17.6 2.4e-65 220.6 17.6 1.4 1 0 0 1 1 1 1 BAR domain of APPL family RhoGAP PF00620.27 KFP19955.1 - 4e-40 137.1 0.1 4e-40 137.1 0.1 2.5 3 0 0 3 3 3 1 RhoGAP domain SH3_9 PF14604.6 KFP19955.1 - 6.4e-10 38.7 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP19955.1 - 2.5e-07 30.2 0.0 4.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFP19955.1 - 1.5e-06 28.6 0.0 6.4e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 KFP19955.1 - 8.5e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Sld5 PF05916.11 KFP19955.1 - 0.46 11.0 3.1 18 5.8 2.9 2.8 1 1 0 1 1 1 0 GINS complex protein zf-C4 PF00105.18 KFP19956.1 - 1.5e-28 99.0 13.0 2.8e-28 98.2 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP19956.1 - 1.3e-13 51.0 0.2 2.1e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Pkinase PF00069.25 KFP19957.1 - 2.3e-73 246.8 0.0 3.6e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.17 KFP19957.1 - 2.4e-41 139.6 0.3 9e-21 73.7 0.0 2.6 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.17 KFP19957.1 - 1.7e-32 112.7 0.0 2.7e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP19957.1 - 0.0042 16.4 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFP19957.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mab-21 PF03281.14 KFP19959.1 - 1.3e-98 330.0 0.0 1.5e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein GDI PF00996.18 KFP19960.1 - 0.08 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor GMC_oxred_N PF00732.19 KFP19960.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 GMC oxidoreductase NCBP3 PF10309.9 KFP19961.1 - 7.2e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFP19961.1 - 0.0042 17.1 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain Arfaptin PF06456.13 KFP19962.1 - 2e-73 246.7 7.5 2.3e-73 246.5 7.5 1.0 1 0 0 1 1 1 1 Arfaptin-like domain BAR_3 PF16746.5 KFP19962.1 - 0.023 14.4 11.1 0.044 13.5 10.9 1.6 1 1 0 1 1 1 0 BAR domain of APPL family BAR_2 PF10455.9 KFP19962.1 - 0.15 11.2 5.3 0.13 11.3 4.4 1.3 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ApoO PF09769.9 KFP19962.1 - 0.23 11.4 0.7 5.5 7.0 0.0 2.6 3 0 0 3 3 3 0 Apolipoprotein O WD40 PF00400.32 KFP19963.1 - 8.1e-17 61.3 11.2 3.8e-08 33.8 0.2 3.9 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP19963.1 - 8.7e-10 38.8 0.2 0.0021 18.3 0.0 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP19963.1 - 1.7e-08 33.6 2.4 0.041 12.5 0.1 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFP19963.1 - 0.0002 20.4 2.3 0.0093 14.9 0.1 2.8 1 1 2 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KFP19963.1 - 0.0008 18.5 0.8 0.2 10.6 0.2 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFP19963.1 - 0.0021 17.7 0.4 0.0086 15.7 0.1 2.0 1 1 1 2 2 2 1 PQQ-like domain Hira PF07569.11 KFP19963.1 - 0.01 15.5 0.6 2.1 8.0 0.0 2.9 1 1 2 3 3 3 0 TUP1-like enhancer of split CDtoxinA PF03498.14 KFP19963.1 - 0.029 14.0 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain BBS2_Mid PF14783.6 KFP19963.1 - 0.1 12.6 0.1 2.1 8.4 0.0 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KFP19963.1 - 0.14 12.1 0.1 25 5.0 0.0 3.7 4 1 1 5 5 5 0 PQQ enzyme repeat TFIID_30kDa PF03540.13 KFP19965.1 - 4.8e-27 93.7 0.0 6.9e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KFP19965.1 - 0.00065 19.7 0.0 0.011 15.7 0.0 2.1 1 1 0 1 1 1 1 Bromodomain associated Pro-kuma_activ PF09286.11 KFP19966.1 - 9.9e-11 42.1 0.0 1.6e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain RepA1_leader PF08048.12 KFP19966.1 - 0.007 16.6 1.3 1.8 8.9 0.0 2.4 2 0 0 2 2 2 2 Tap RepA1 leader peptide LCM PF04072.14 KFP19967.1 - 2.3e-28 99.4 0.0 3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 KFP19967.1 - 2.2e-13 49.8 1.1 0.08 13.0 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KFP19967.1 - 5.8e-13 48.6 1.1 0.072 13.1 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFP19967.1 - 4.8e-10 39.4 2.8 0.011 16.0 0.0 5.3 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KFP19967.1 - 2.8e-06 27.0 5.1 0.13 12.3 0.3 4.9 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KFP19967.1 - 0.0013 18.2 6.0 0.041 13.5 0.1 4.1 5 0 0 5 5 5 1 Kelch motif Glyoxal_oxid_N PF07250.11 KFP19967.1 - 0.058 12.6 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 KFP19967.1 - 2.2 8.7 6.8 15 6.0 0.2 4.4 4 1 0 4 4 4 0 Galactose oxidase, central domain BAR PF03114.18 KFP19968.1 - 2.2e-50 171.5 7.2 2.2e-50 171.5 7.2 1.5 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.6 KFP19968.1 - 6.9e-09 35.4 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP19968.1 - 1.7e-06 27.6 0.1 1.8e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP19968.1 - 0.0003 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFP19968.1 - 0.0011 18.7 2.6 0.0024 17.6 2.5 1.5 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 KFP19968.1 - 0.0064 16.1 3.8 0.0097 15.5 3.8 1.3 1 0 0 1 1 1 1 Arfaptin-like domain EzrA PF06160.12 KFP19968.1 - 0.019 13.2 4.7 0.6 8.2 0.5 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HD_3 PF13023.6 KFP19968.1 - 0.043 13.7 0.2 0.043 13.7 0.2 2.4 2 1 1 3 3 3 0 HD domain Jnk-SapK_ap_N PF09744.9 KFP19968.1 - 0.97 9.6 9.5 0.23 11.7 2.2 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 KFP19968.1 - 5.3 7.8 6.1 2.7 8.8 1.0 2.5 2 0 0 2 2 2 0 Occludin homology domain Btz PF09405.10 KFP19969.1 - 8.9e-23 81.0 4.6 8.9e-23 81.0 4.6 3.2 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding PEHE PF15275.6 KFP19970.1 - 1e-21 77.9 2.1 1.1e-21 77.8 0.2 2.0 2 0 0 2 2 2 1 PEHE domain tRNA-synt_1c PF00749.21 KFP19970.1 - 0.062 12.2 0.1 0.094 11.6 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain GTP_EFTU_D3 PF03143.17 KFP19971.1 - 3.2e-40 136.9 0.0 6.7e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 KFP19971.1 - 1.3e-39 135.8 0.0 1.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFP19971.1 - 5.1e-15 55.6 0.4 1.3e-14 54.3 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KFP19971.1 - 0.022 14.6 0.9 0.04 13.8 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KFP19971.1 - 0.043 13.9 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase KCNQ_channel PF03520.14 KFP19972.1 - 1.3e-83 279.5 0.0 3.2e-83 278.2 0.0 1.7 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.8 KFP19972.1 - 1.1e-45 154.2 1.0 1.1e-45 154.2 1.0 1.8 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 KCNQ2_u3 PF16642.5 KFP19972.1 - 9.7e-37 125.9 10.9 9.7e-37 125.9 10.9 2.7 3 0 0 3 3 3 1 Unstructured region on Potassium channel subunit alpha KvLQT2 Ion_trans PF00520.31 KFP19972.1 - 1.8e-29 102.7 5.9 1.8e-29 102.7 5.9 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 KFP19972.1 - 2e-13 50.1 3.1 5.4e-13 48.7 3.1 1.7 1 0 0 1 1 1 1 Ion channel fn3 PF00041.21 KFP19973.1 - 8.5e-78 256.8 15.8 3.1e-16 59.5 0.6 6.4 6 0 0 6 6 6 6 Fibronectin type III domain VWA PF00092.28 KFP19973.1 - 1.6e-48 165.3 0.0 2.9e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Collagen PF01391.18 KFP19973.1 - 8.1e-40 134.4 157.4 1.9e-09 37.1 35.2 5.3 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 KFP19973.1 - 3.1e-13 50.3 0.0 6.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Pur_ac_phosph_N PF16656.5 KFP19973.1 - 2.1e-08 34.6 15.4 0.91 10.1 1.6 7.3 5 3 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFP19973.1 - 3e-08 33.9 0.5 1.1 9.7 0.0 6.1 6 0 0 6 6 6 2 Uncharacterised conserved protein (DUF2369) VWA_3 PF13768.6 KFP19973.1 - 9.2e-06 25.7 0.1 3.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain CBM_4_9 PF02018.17 KFP19973.1 - 0.00011 22.5 0.7 0.0058 16.9 0.1 3.2 3 0 0 3 3 3 1 Carbohydrate binding domain DUF4998 PF16389.5 KFP19973.1 - 0.0031 17.1 0.0 0.7 9.4 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function Glyco_hydro_36C PF16874.5 KFP19973.1 - 0.0064 17.0 0.0 70 4.0 0.0 4.6 4 0 0 4 4 4 0 Glycosyl hydrolase family 36 C-terminal domain DEP PF00610.21 KFP19974.1 - 1.1e-44 150.3 1.3 3.7e-22 78.2 0.1 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFP19974.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP19974.1 - 0.049 14.0 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 KFP19974.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain ArfGap PF01412.18 KFP19975.1 - 8.1e-33 113.0 0.5 8.1e-33 113.0 0.5 3.2 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.13 KFP19975.1 - 0.028 14.5 1.4 0.073 13.2 1.4 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.19 KFP19975.1 - 0.046 13.8 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family NKAIN PF05640.14 KFP19976.1 - 9.7e-93 309.2 5.8 1.1e-92 309.0 5.8 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.11 KFP19976.1 - 0.055 13.6 1.0 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) BIR PF00653.21 KFP19977.1 - 7.2e-42 141.9 15.4 6.1e-23 81.3 1.0 2.7 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 KFP19977.1 - 1.9e-14 53.3 7.3 1.9e-14 53.3 7.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP19977.1 - 1.1e-06 28.4 7.1 1.1e-06 28.4 7.1 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP19977.1 - 0.00081 19.7 8.4 0.00081 19.7 8.4 2.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP19977.1 - 0.0028 17.4 6.2 0.0028 17.4 6.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 KFP19977.1 - 0.028 14.8 2.2 0.051 13.9 2.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) GAGA PF09237.11 KFP19977.1 - 0.061 13.1 0.9 0.16 11.8 0.9 1.7 1 0 0 1 1 1 0 GAGA factor YTH PF04146.15 KFP19978.1 - 4.1e-42 144.0 0.4 1.2e-41 142.4 0.4 1.8 1 1 0 1 1 1 1 YT521-B-like domain MFS_1 PF07690.16 KFP19979.1 - 2.7e-45 154.8 26.8 2.7e-45 154.8 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CLTH PF10607.9 KFP19980.1 - 2.6e-34 118.3 5.2 3.3e-34 117.9 5.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFP19980.1 - 1.2e-12 47.3 0.5 4.7e-11 42.2 0.1 2.7 2 0 0 2 2 2 1 LisH SPOC PF07744.13 KFP19981.1 - 5.8e-29 101.0 0.0 1.6e-28 99.6 0.0 1.8 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KFP19981.1 - 1.4e-26 93.2 2.7 1.4e-26 93.2 2.7 2.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KFP19981.1 - 3.9e-11 42.7 8.0 9.6e-11 41.4 8.0 1.7 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KFP19981.1 - 0.1 13.0 0.2 1.2 9.6 0.2 3.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx SlyX PF04102.12 KFP19981.1 - 1.6 9.4 9.7 0.057 14.0 2.2 2.7 2 0 0 2 2 2 0 SlyX HLH PF00010.26 KFP19982.1 - 4e-10 39.5 0.5 1.5e-09 37.6 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Collagen PF01391.18 KFP19983.1 - 4.3e-18 64.8 58.2 2.1e-10 40.2 30.2 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) OGFr_N PF04664.13 KFP19984.1 - 3.4e-104 346.9 8.8 4.7e-104 346.4 8.8 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Eaf7 PF07904.13 KFP19985.1 - 7.1e-08 32.8 3.3 2e-07 31.4 3.3 2.2 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Asp-B-Hydro_N PF05279.11 KFP19985.1 - 0.026 14.6 4.0 0.029 14.4 4.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 7tm_1 PF00001.21 KFP19986.1 - 4.2e-14 52.5 7.2 5.1e-14 52.2 7.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) OATP PF03137.20 KFP19987.1 - 1.4e-180 601.2 14.2 1.9e-180 600.8 14.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFP19987.1 - 2e-15 56.6 27.9 2e-15 56.6 27.9 3.1 2 2 0 2 2 2 1 Major Facilitator Superfamily Kazal_2 PF07648.15 KFP19987.1 - 8.9e-09 35.3 10.3 3e-08 33.7 10.3 2.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KFP19987.1 - 0.025 14.6 6.2 0.093 12.8 6.2 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain GATA PF00320.27 KFP19988.1 - 1.4e-29 101.4 16.3 9.2e-16 57.2 5.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KFP19988.1 - 2e-05 24.0 9.5 0.016 14.7 3.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFP19988.1 - 0.0027 17.7 0.8 0.18 11.9 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF2387 PF09526.10 KFP19988.1 - 0.014 15.5 3.7 4.5 7.5 0.4 3.1 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.17 KFP19988.1 - 0.05 13.5 8.4 2.4 8.0 2.8 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 KFP19988.1 - 0.16 12.1 7.2 1.9 8.7 1.4 2.8 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KFP19988.1 - 0.17 12.0 8.2 9.9 6.3 1.5 2.8 1 1 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 KFP19988.1 - 0.37 11.0 8.9 0.37 11.0 0.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) C1_1 PF00130.22 KFP19988.1 - 0.51 10.3 5.9 9.1 6.3 0.3 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 KFP19988.1 - 1.3 8.9 9.0 2.2 8.2 0.6 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.5 KFP19988.1 - 1.4 8.4 12.3 0.13 11.7 1.6 3.7 2 2 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cytochrom_c3_2 PF14537.6 KFP19988.1 - 2.1 8.9 6.4 0.31 11.5 0.5 2.3 2 1 0 2 2 2 0 Cytochrome c3 CtIP_N PF10482.9 KFP19989.1 - 1e-54 183.7 19.3 1e-54 183.7 19.3 1.9 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 KFP19989.1 - 0.072 13.5 0.5 0.072 13.5 0.5 3.5 4 0 0 4 4 3 0 Cell division protein ZapB bZIP_1 PF00170.21 KFP19989.1 - 0.09 12.9 13.8 0.46 10.6 1.5 3.4 2 1 1 3 3 3 0 bZIP transcription factor Plant_NMP1 PF06694.11 KFP19989.1 - 0.1 11.7 0.7 0.16 11.0 0.7 1.3 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) TSC22 PF01166.18 KFP19989.1 - 0.16 12.3 10.8 0.66 10.3 1.0 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family Atg14 PF10186.9 KFP19989.1 - 0.25 10.4 14.1 0.0079 15.3 8.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KFP19989.1 - 0.69 9.7 16.6 0.083 12.7 0.6 3.3 3 1 0 3 3 3 0 Septum formation initiator NRBF2 PF08961.10 KFP19989.1 - 1.2 8.7 17.8 0.099 12.2 4.3 3.0 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Prominin PF05478.11 KFP19989.1 - 4.1 5.2 7.0 7.1 4.4 7.0 1.3 1 0 0 1 1 1 0 Prominin HI0933_like PF03486.14 KFP19989.1 - 4.3 5.9 5.9 3 6.4 4.3 1.5 2 0 0 2 2 2 0 HI0933-like protein DUF4618 PF15397.6 KFP19989.1 - 4.4 6.6 17.2 2.4 7.5 3.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) SidE PF12252.8 KFP19989.1 - 4.9 4.6 8.0 6.7 4.1 8.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein DivIVA PF05103.13 KFP19989.1 - 5 7.2 10.4 9.1 6.4 2.3 2.8 1 1 1 2 2 2 0 DivIVA protein SKA2 PF16740.5 KFP19989.1 - 5.3 6.9 15.0 2.5 7.9 2.0 3.0 2 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 FapA PF03961.13 KFP19989.1 - 6.9 5.2 7.4 11 4.5 7.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Latarcin PF10279.9 KFP19989.1 - 7.9 7.0 8.4 4 7.9 0.3 2.9 2 1 0 2 2 2 0 Latarcin precursor JIP_LZII PF16471.5 KFP19989.1 - 8 6.7 13.8 2 8.7 0.9 3.4 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II Spc24 PF08286.11 KFP19989.1 - 8.8 6.6 12.4 9.5 6.5 1.4 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cyclin_N PF00134.23 KFP19990.1 - 2.3e-09 37.1 0.5 4e-09 36.3 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain HGTP_anticodon PF03129.20 KFP19990.1 - 0.14 12.4 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 Anticodon binding domain Laminin_EGF PF00053.24 KFP19991.1 - 1.6e-147 479.6 425.1 2.1e-11 43.8 14.7 22.8 20 3 3 23 23 23 21 Laminin EGF domain Laminin_N PF00055.17 KFP19991.1 - 2e-67 227.2 0.0 2e-67 227.2 0.0 2.5 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_G_2 PF02210.24 KFP19991.1 - 2.5e-62 209.0 0.0 4.2e-21 75.8 0.0 6.4 6 0 0 6 6 6 5 Laminin G domain Laminin_I PF06008.14 KFP19991.1 - 2.7e-49 168.2 38.9 2.7e-49 168.2 38.9 2.4 2 1 0 2 2 2 1 Laminin Domain I Laminin_G_1 PF00054.23 KFP19991.1 - 1.9e-48 164.0 0.0 1.9e-18 67.0 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_B PF00052.18 KFP19991.1 - 4.4e-38 130.2 1.6 8.4e-38 129.3 0.0 2.3 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_II PF06009.12 KFP19991.1 - 2.3e-36 124.8 5.4 2.3e-36 124.8 5.4 5.0 3 2 3 6 6 6 2 Laminin Domain II Laminin_G_3 PF13385.6 KFP19991.1 - 9e-13 48.6 0.0 0.00013 22.1 0.0 3.5 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily RPN13_C PF16550.5 KFP19992.1 - 4.7e-36 123.4 2.2 8e-36 122.6 2.2 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KFP19992.1 - 3.6e-33 114.0 0.1 6.5e-33 113.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.6 KFP19992.1 - 0.0089 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Asx homology domain GerD PF17898.1 KFP19992.1 - 0.028 14.4 1.0 0.096 12.6 0.1 2.0 2 0 0 2 2 2 0 Spore germination GerD central core domain Dak2 PF02734.17 KFP19992.1 - 0.042 13.8 0.2 0.067 13.1 0.2 1.3 1 0 0 1 1 1 0 DAK2 domain GTP1_OBG PF01018.22 KFP19993.1 - 4.8e-47 159.4 7.1 6.3e-47 159.0 7.1 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KFP19993.1 - 6.2e-25 87.5 0.0 9.4e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFP19993.1 - 7.1e-12 45.1 0.0 2e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KFP19993.1 - 0.00021 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KFP19993.1 - 0.00078 19.5 0.0 0.19 11.8 0.0 2.2 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 KFP19993.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.6 1 1 0 1 1 1 0 Ras family Roc PF08477.13 KFP19993.1 - 0.023 14.9 0.0 0.24 11.6 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP19993.1 - 0.07 12.5 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KFP19993.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 KFP19993.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SSXT PF05030.12 KFP19994.1 - 9.2e-33 111.7 5.0 2.4e-32 110.3 5.0 1.8 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Elf4 PF07011.11 KFP19994.1 - 0.027 14.4 1.6 1.3 9.0 0.1 2.5 1 1 1 2 2 2 0 Early Flowering 4 domain Proteasome PF00227.26 KFP19995.1 - 1.6e-60 203.8 0.1 1.9e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF5069 PF16798.5 KFP19995.1 - 0.095 12.9 0.2 0.92 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Hormone_3 PF00159.18 KFP19995.1 - 0.1 12.7 0.5 4.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Pancreatic hormone peptide FDF PF09532.10 KFP19996.1 - 1.2e-24 87.2 9.0 1.2e-24 87.2 9.0 1.8 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 KFP19996.1 - 2.2e-12 46.9 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Cadherin PF00028.17 KFP19997.1 - 2.9e-86 284.1 6.1 7e-22 77.7 1.2 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP19997.1 - 8.8e-52 175.3 0.6 1.9e-51 174.2 0.6 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.11 KFP19997.1 - 2.2e-17 63.0 0.0 1.2e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_3 PF16184.5 KFP19997.1 - 1.1e-06 28.6 7.7 0.0069 16.4 0.2 4.5 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFP19997.1 - 7e-05 22.6 0.0 2.7 7.9 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like He_PIG PF05345.12 KFP19997.1 - 0.00012 22.2 7.2 0.028 14.6 0.3 4.9 5 0 0 5 5 5 1 Putative Ig domain Stevor PF17410.2 KFP19997.1 - 0.035 13.6 0.2 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cadherin_4 PF17803.1 KFP19997.1 - 0.036 14.7 26.0 0.17 12.5 0.8 5.4 6 0 0 6 6 5 0 Bacterial cadherin-like domain PKD PF00801.20 KFP19997.1 - 0.043 13.7 0.7 1.4 8.8 0.1 3.4 4 0 0 4 4 4 0 PKD domain EphA2_TM PF14575.6 KFP19997.1 - 0.061 14.2 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5527 PF17665.1 KFP19997.1 - 0.15 11.6 1.4 0.21 11.1 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Big_9 PF17963.1 KFP19997.1 - 2.9 8.7 23.5 0.29 11.9 1.1 4.6 4 1 1 5 5 4 0 Bacterial Ig domain FAM217 PF15344.6 KFP19998.1 - 4.2e-89 298.6 3.9 5.8e-89 298.1 3.9 1.2 1 0 0 1 1 1 1 FAM217 family CBM_21 PF03370.13 KFP20000.1 - 6.4e-33 113.3 0.2 9.4e-33 112.8 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFP20000.1 - 4.2e-14 52.9 0.4 9.1e-14 51.8 0.4 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_25 PF03423.13 KFP20000.1 - 0.016 15.5 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) RPEL PF02755.15 KFP20001.1 - 6.2e-21 73.4 21.3 9.8e-07 28.3 3.2 4.7 4 0 0 4 4 4 4 RPEL repeat Sod_Ni PF09055.11 KFP20001.1 - 0.015 15.9 1.0 0.05 14.2 1.0 1.9 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase zf-C2H2_jaz PF12171.8 KFP20004.1 - 0.026 14.8 0.4 0.043 14.1 0.4 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-RRN7 PF11781.8 KFP20004.1 - 0.084 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PRELI PF04707.14 KFP20005.1 - 1.3e-56 190.8 0.0 1.5e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ATP-synt_Eps PF04627.13 KFP20006.1 - 2.7e-13 49.7 1.7 2.9e-13 49.5 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Tubulin PF00091.25 KFP20007.1 - 1.1e-70 237.9 0.0 1.5e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP20007.1 - 1.6e-40 138.2 0.0 2.6e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFP20007.1 - 2.7e-05 24.4 0.0 6.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFP20007.1 - 0.0047 16.2 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KFP20007.1 - 0.0047 16.6 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Peptidase_C1 PF00112.23 KFP20008.1 - 6.2e-40 137.6 6.5 7.7e-40 137.3 6.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KFP20008.1 - 0.069 11.9 0.4 0.17 10.6 0.4 1.5 2 0 0 2 2 2 0 Peptidase C1-like family TH1 PF04858.13 KFP20009.1 - 3.7e-282 937.2 0.8 4.2e-282 937.0 0.8 1.0 1 0 0 1 1 1 1 TH1 protein CARD_2 PF16739.5 KFP20009.1 - 0.09 12.8 0.1 5.8 7.0 0.0 3.4 2 1 1 3 3 3 0 Caspase recruitment domain G-alpha PF00503.20 KFP20010.1 - 5.4e-103 344.9 1.4 6.1e-103 344.7 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP20010.1 - 1.9e-14 53.5 1.5 1.4e-13 50.7 0.5 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFP20010.1 - 0.001 19.3 1.6 0.028 14.6 0.2 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP20010.1 - 0.021 14.4 0.0 0.33 10.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M17 PF00883.21 KFP20011.1 - 7.7e-101 337.5 0.1 9.8e-101 337.1 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KFP20011.1 - 4.7e-17 62.4 0.3 1.7e-16 60.6 0.1 2.0 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 Syntaxin PF00804.25 KFP20012.1 - 3.9e-08 33.2 8.9 8.5e-08 32.1 8.9 1.5 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFP20012.1 - 4.3e-05 23.4 0.1 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 1 SNARE domain DUF3140 PF11338.8 KFP20012.1 - 0.028 14.8 0.2 0.072 13.5 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) Syntaxin_2 PF14523.6 KFP20012.1 - 0.051 13.9 10.2 0.11 12.9 6.5 2.4 2 1 0 2 2 2 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 KFP20012.1 - 0.28 11.7 6.3 2.3 8.8 4.1 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4456 PF14644.6 KFP20012.1 - 0.54 9.9 9.2 0.21 11.3 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) TMPIT PF07851.13 KFP20012.1 - 0.9 8.7 4.7 0.65 9.2 2.7 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF733 PF05306.11 KFP20012.1 - 2.5 8.4 6.5 75 3.7 6.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF733) Exonuc_VII_L PF02601.15 KFP20012.1 - 5 6.6 9.0 7.6 6.0 9.0 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4592 PF15262.6 KFP20013.1 - 3.9e-32 111.7 3.6 3.9e-32 111.7 3.6 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4592) SH2 PF00017.24 KFP20017.1 - 2e-18 66.3 0.1 3e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Nucleos_tra2_C PF07662.13 KFP20018.1 - 4.6e-78 261.8 5.4 4.6e-78 261.8 5.4 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KFP20018.1 - 4.3e-20 72.1 3.9 4.3e-20 72.1 3.9 3.9 3 1 2 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KFP20018.1 - 1.5e-09 38.1 6.0 1.5e-09 38.1 6.0 3.4 4 1 0 4 4 4 1 Nucleoside recognition Peptidase_C14 PF00656.22 KFP20019.1 - 6.1e-21 75.5 0.0 5.2e-20 72.4 0.0 1.9 1 1 0 1 1 1 1 Caspase domain Peptidase_S24 PF00717.23 KFP20020.1 - 3.7e-09 36.4 0.1 6.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DuoxA PF10204.9 KFP20021.1 - 1.2e-114 382.1 12.1 1.4e-114 381.9 12.1 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor An_peroxidase PF03098.15 KFP20022.1 - 2.3e-134 448.9 0.0 3.7e-134 448.2 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.12 KFP20022.1 - 4e-30 105.0 0.0 1.2e-29 103.5 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFP20022.1 - 7.7e-19 68.0 17.1 2e-18 66.7 17.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFP20022.1 - 1.1e-17 64.1 0.0 2.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain EF-hand_1 PF00036.32 KFP20022.1 - 1.2e-14 52.7 5.4 6.1e-07 28.6 0.5 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP20022.1 - 1.3e-10 41.6 9.4 5.1e-07 30.0 2.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP20022.1 - 2.5e-10 39.4 5.2 0.00058 19.6 0.4 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFP20022.1 - 9.6e-10 38.2 7.2 1.1e-05 25.2 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP20022.1 - 2.7e-08 32.9 2.9 0.0029 17.0 0.3 3.0 2 0 0 2 2 2 2 EF hand NAD_binding_1 PF00175.21 KFP20022.1 - 0.00063 20.4 0.2 0.063 13.9 0.0 3.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain ADH_N PF08240.12 KFP20023.1 - 1.4e-24 86.1 0.1 3.3e-24 84.9 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFP20023.1 - 1.1e-21 77.2 0.4 2.5e-21 76.0 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFP20023.1 - 2.1e-08 33.9 2.9 4.9e-08 32.7 1.4 2.2 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFP20023.1 - 4.6e-05 22.8 0.6 7.8e-05 22.1 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFP20023.1 - 0.022 15.8 0.0 0.048 14.7 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF281 PF03436.13 KFP20023.1 - 0.04 14.3 0.1 0.14 12.6 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF281) DUF2249 PF10006.9 KFP20023.1 - 0.051 13.5 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) RRM_1 PF00076.22 KFP20025.1 - 5.9e-12 45.2 0.0 9.3e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP20025.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 KFP20025.1 - 0.17 12.1 0.1 1.1 9.5 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ASCH PF04266.14 KFP20028.1 - 5.4e-18 65.5 0.0 1.1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 KFP20028.1 - 1.2e-10 41.2 11.1 2.5e-10 40.2 11.1 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type CK1gamma_C PF12605.8 KFP20029.1 - 2.6e-31 108.7 5.0 5.3e-31 107.7 5.0 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase PF00069.25 KFP20029.1 - 4.1e-26 91.9 0.0 5.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20029.1 - 1.7e-14 53.8 0.0 2.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP20029.1 - 2e-08 33.4 0.2 3.1e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 KFP20029.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pro_isomerase PF00160.21 KFP20031.1 - 8.8e-51 172.3 0.3 9.8e-51 172.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Vps5 PF09325.10 KFP20032.1 - 2e-82 276.3 21.1 2e-82 276.3 21.1 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KFP20032.1 - 4e-28 97.7 1.0 1.5e-27 95.8 0.1 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KFP20032.1 - 3.4e-05 23.4 2.9 0.0032 17.0 2.9 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FUSC PF04632.12 KFP20032.1 - 0.076 11.5 6.0 0.11 11.0 6.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2833 PF11090.8 KFP20032.1 - 0.52 10.7 2.3 0.56 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) HR1 PF02185.16 KFP20032.1 - 0.9 9.7 7.2 1.4 9.0 1.2 2.9 2 0 0 2 2 2 0 Hr1 repeat Arfaptin PF06456.13 KFP20032.1 - 1.6 8.2 13.5 0.04 13.5 3.5 2.4 2 0 0 2 2 2 0 Arfaptin-like domain DUF2043 PF09740.9 KFP20032.1 - 2.9 8.6 6.8 2.7 8.7 3.9 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) PAT1 PF09770.9 KFP20033.1 - 2.4e-16 59.2 0.7 1.3e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 KFP20034.1 - 2.8e-14 53.7 0.0 3.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Ribosomal_S17e PF00833.18 KFP20035.1 - 7.3e-34 116.3 0.1 8.1e-34 116.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 CEBP1_N PF16368.5 KFP20036.1 - 5.6e-159 528.6 15.8 7e-159 528.3 15.8 1.1 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein 1 N-terminus RRM_7 PF16367.5 KFP20036.1 - 2e-36 124.0 0.0 5.1e-36 122.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif CEBP_ZZ PF16366.5 KFP20036.1 - 8.4e-25 86.8 7.6 8.4e-25 86.8 7.6 1.7 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFP20036.1 - 3.3e-08 33.2 0.0 0.0097 15.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.20 KFP20037.1 - 1e-176 588.6 21.4 1.2e-176 588.4 21.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 KFP20037.1 - 2.6e-52 177.0 0.0 5.8e-52 175.9 0.0 1.6 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 KFP20037.1 - 3.5e-23 82.4 10.2 4.3e-19 69.1 1.0 3.7 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFP20037.1 - 2.3e-08 34.3 7.1 0.00021 21.6 0.2 5.3 3 3 3 6 6 6 2 HEAT repeats HEAT PF02985.22 KFP20037.1 - 2.1e-06 27.5 3.1 1.6 9.2 0.0 6.2 6 0 0 6 6 5 2 HEAT repeat HEAT_EZ PF13513.6 KFP20037.1 - 0.0031 18.0 2.9 4.1 8.0 0.0 5.3 4 2 3 7 7 7 1 HEAT-like repeat DUF4890 PF16231.5 KFP20037.1 - 2.1 8.9 0.0 2.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4890) TFIIF_alpha PF05793.12 KFP20037.1 - 2.6 6.5 33.7 4.3 5.8 33.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 KFP20037.1 - 5.8 5.6 16.7 11 4.7 16.7 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain NOA36 PF06524.12 KFP20037.1 - 7.1 5.9 10.8 13 5.0 10.8 1.4 1 0 0 1 1 1 0 NOA36 protein SOBP PF15279.6 KFP20037.1 - 7.6 7.1 9.0 16 6.0 9.0 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein NLPC_P60 PF00877.19 KFP20038.1 - 0.0036 17.3 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.13 KFP20038.1 - 0.0059 16.9 0.0 0.0072 16.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Hormone_recep PF00104.30 KFP20039.1 - 2.1e-30 105.8 0.1 9.5e-30 103.7 0.1 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP20039.1 - 3.8e-28 97.7 14.2 4.3e-28 97.6 12.5 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Myosin_head PF00063.21 KFP20040.1 - 1.5e-214 714.1 10.7 2.9e-186 620.7 5.7 2.4 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.27 KFP20040.1 - 5.8e-48 162.6 0.1 8.2e-47 158.8 0.0 2.9 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 KFP20040.1 - 3.2e-22 79.0 0.0 1.9e-21 76.5 0.0 2.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IQ PF00612.27 KFP20040.1 - 6e-21 72.2 39.0 0.00015 21.3 2.0 6.9 5 1 1 6 6 6 5 IQ calmodulin-binding motif C1_1 PF00130.22 KFP20040.1 - 6.9e-06 25.9 12.1 1.3e-05 24.9 12.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APG6_N PF17675.1 KFP20040.1 - 0.0084 16.6 1.7 0.0084 16.6 1.7 3.7 3 0 0 3 3 3 1 Apg6 coiled-coil region AAA_16 PF13191.6 KFP20040.1 - 0.027 14.9 1.1 0.24 11.8 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 KFP20040.1 - 0.03 13.4 0.1 0.18 10.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KFP20040.1 - 0.04 14.2 4.2 0.07 13.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain IQCJ-SCHIP1 PF15157.6 KFP20040.1 - 0.98 9.2 4.7 22 4.8 0.2 4.5 4 1 1 5 5 5 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF5320 PF17253.2 KFP20040.1 - 9.2 7.4 6.8 5 8.3 0.2 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Peptidase_C48 PF02902.19 KFP20041.1 - 3.8e-13 49.8 0.6 1.5e-12 47.9 0.6 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GRAM PF02893.20 KFP20042.1 - 6.8e-21 74.3 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain CC2D2AN-C2 PF15625.6 KFP20042.1 - 0.013 15.3 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain PK PF00224.21 KFP20043.1 - 1.1e-169 563.9 3.7 1.3e-169 563.6 3.7 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFP20043.1 - 2.8e-34 117.8 0.0 1.4e-33 115.6 0.0 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFP20043.1 - 0.00042 19.5 0.2 0.00094 18.4 0.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RRM_1 PF00076.22 KFP20044.1 - 9.9e-16 57.3 0.0 1.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP20044.1 - 0.024 14.8 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Glyco_hydro_20 PF00728.22 KFP20045.1 - 3.3e-85 286.6 0.0 5.1e-85 286.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFP20045.1 - 1.7e-09 38.4 0.0 2.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFP20045.1 - 0.0011 19.7 0.0 0.002 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 IBR PF01485.21 KFP20046.1 - 1.6e-18 66.7 44.1 3.1e-14 52.9 10.1 5.1 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KFP20046.1 - 4.3e-06 26.5 2.6 4.3e-06 26.5 2.6 4.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP20046.1 - 0.00035 20.4 3.8 0.00035 20.4 3.8 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP20046.1 - 0.001 19.0 4.2 0.001 19.0 4.2 4.8 4 1 0 4 4 4 1 RING-type zinc-finger zf-RING_14 PF17978.1 KFP20046.1 - 0.0012 19.2 1.9 0.0012 19.2 1.9 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KFP20046.1 - 0.0013 19.0 6.1 0.0013 19.0 6.1 4.5 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFP20046.1 - 0.0019 18.3 5.1 0.0019 18.3 5.1 4.7 4 1 1 5 5 5 2 zinc finger of C3HC4-type, RING OmpH PF03938.14 KFP20046.1 - 0.16 12.3 5.2 0.097 13.0 1.5 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Med14 PF08638.11 KFP20046.1 - 0.59 9.5 4.5 0.13 11.7 0.4 2.0 3 0 0 3 3 3 0 Mediator complex subunit MED14 TPR_2 PF07719.17 KFP20048.1 - 2.2e-44 146.0 17.8 2.4e-06 27.2 0.1 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFP20048.1 - 9.4e-42 139.2 18.3 2.7e-06 26.9 0.1 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFP20048.1 - 4.7e-36 120.0 16.8 1.9e-05 24.5 0.0 9.1 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 KFP20048.1 - 2.1e-30 104.1 10.0 1.2e-08 34.5 0.0 8.6 3 2 6 9 9 9 5 TPR repeat TPR_19 PF14559.6 KFP20048.1 - 3.2e-26 91.6 4.3 2.9e-06 27.7 0.1 6.9 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KFP20048.1 - 6.1e-24 84.4 0.1 0.0024 18.5 0.0 6.8 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP20048.1 - 2.5e-21 75.7 19.7 1.2e-05 25.5 0.1 7.6 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFP20048.1 - 6.9e-21 73.2 1.6 0.0012 19.5 0.0 8.0 3 2 6 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP20048.1 - 2.4e-19 68.3 14.7 2.7e-05 24.3 0.0 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP20048.1 - 2.3e-18 66.2 21.3 4.2e-06 26.9 0.7 6.1 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFP20048.1 - 4.5e-18 65.2 0.0 1.9e-05 24.7 0.0 5.6 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP20048.1 - 6.8e-18 63.3 8.3 0.0019 18.1 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP20048.1 - 1.9e-14 53.2 8.4 0.54 11.0 0.0 10.1 10 0 0 10 10 10 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFP20048.1 - 7.2e-10 38.1 1.0 0.0095 14.7 0.0 3.1 2 1 1 3 3 3 3 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 KFP20048.1 - 2.3e-09 36.9 5.0 6.7e-05 22.2 0.1 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat NARP1 PF12569.8 KFP20048.1 - 5.9e-09 35.4 2.1 0.015 14.2 0.1 3.5 2 2 1 3 3 3 3 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 KFP20048.1 - 1.4e-07 31.7 1.2 0.032 14.2 0.0 4.2 2 2 2 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal TPR_20 PF14561.6 KFP20048.1 - 2.7e-06 27.6 3.0 0.013 15.8 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP20048.1 - 3.5e-06 26.7 14.4 0.59 10.1 0.1 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KFP20048.1 - 6.9e-05 22.4 4.1 0.58 9.5 0.5 3.5 2 1 0 3 3 3 1 Coatomer epsilon subunit ChAPs PF09295.10 KFP20048.1 - 7.1e-05 22.0 1.0 0.0044 16.1 0.1 2.7 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 KFP20048.1 - 0.00068 19.1 2.5 0.051 13.0 0.0 3.3 2 1 1 3 3 3 1 MalT-like TPR region ComR_TPR PF18710.1 KFP20048.1 - 0.0013 18.3 0.5 0.27 10.8 0.1 2.5 2 0 0 2 2 2 1 ComR tetratricopeptide HrpB1_HrpK PF09613.10 KFP20048.1 - 0.0084 15.8 0.2 1.6 8.4 0.1 2.8 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 KFP20048.1 - 0.016 15.2 7.8 6.2 7.0 0.0 4.9 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 KFP20048.1 - 0.022 14.7 5.2 17 5.4 0.2 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF627) DUF4810 PF16068.5 KFP20048.1 - 0.048 14.2 4.5 26 5.5 0.0 4.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4810) DUF3808 PF10300.9 KFP20048.1 - 0.051 12.3 7.5 0.081 11.6 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3808) BTAD PF03704.17 KFP20048.1 - 0.054 13.9 5.1 18 5.7 0.1 4.4 3 2 1 4 4 4 0 Bacterial transcriptional activator domain Mu-like_Pro PF10123.9 KFP20048.1 - 0.097 12.2 2.2 0.57 9.7 1.7 2.3 2 1 0 2 2 2 0 Mu-like prophage I protein Csm1_B PF18211.1 KFP20048.1 - 0.22 11.4 1.2 5.9 6.8 0.1 3.0 2 1 1 3 3 3 0 Csm1 subunit domain B Clathrin PF00637.20 KFP20048.1 - 0.26 11.1 5.1 3.4 7.5 0.1 3.1 2 1 1 3 3 3 0 Region in Clathrin and VPS ADP_PFK_GK PF04587.15 KFP20049.1 - 1.1e-135 452.5 0.0 1.2e-135 452.4 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Neogenin_C PF06583.12 KFP20050.1 - 2.4e-125 418.2 23.0 5.2e-125 417.1 23.0 1.6 1 0 0 1 1 1 1 Neogenin C-terminus fn3 PF00041.21 KFP20050.1 - 1.1e-83 275.6 28.6 3.9e-18 65.6 0.1 6.4 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.16 KFP20050.1 - 5.5e-54 180.2 0.0 3e-16 59.3 0.0 6.6 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP20050.1 - 5.1e-46 155.2 0.3 3.2e-11 43.7 0.0 7.1 6 0 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFP20050.1 - 1.1e-31 109.0 0.0 1.5e-06 28.4 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFP20050.1 - 1.1e-23 83.2 0.0 6.2e-06 26.3 0.0 6.4 6 1 0 6 6 6 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP20050.1 - 1.3e-21 77.0 23.5 0.0004 20.9 2.9 7.7 6 2 0 6 6 6 5 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFP20050.1 - 1e-14 54.6 4.5 0.00043 20.4 0.1 9.0 6 3 2 8 8 8 1 Immunoglobulin V-set domain Interfer-bind PF09294.10 KFP20050.1 - 3.7e-13 49.7 0.1 0.083 13.2 0.0 5.9 6 0 0 6 6 6 3 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFP20050.1 - 1.7e-08 34.7 1.1 4.4 7.8 0.0 6.1 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) C2-set_2 PF08205.12 KFP20050.1 - 3.2e-07 30.3 0.0 0.61 10.2 0.0 4.3 4 0 0 4 4 3 2 CD80-like C2-set immunoglobulin domain fn3_4 PF16794.5 KFP20050.1 - 1.3e-06 28.3 0.7 2.5 8.1 0.0 5.6 5 1 0 5 5 5 1 Fibronectin-III type domain Tissue_fac PF01108.17 KFP20050.1 - 6.9e-06 25.9 5.5 0.012 15.5 0.0 5.3 5 1 1 6 6 6 1 Tissue factor fn3_2 PF16893.5 KFP20050.1 - 8.4e-06 25.9 0.0 0.89 9.8 0.0 4.4 4 0 0 4 4 4 1 Fibronectin type III domain Ig_5 PF16681.5 KFP20050.1 - 2.4e-05 24.7 0.0 0.53 10.7 0.0 4.4 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain SusE PF14292.6 KFP20050.1 - 0.00037 20.7 0.3 0.11 12.8 0.1 4.0 4 0 0 4 4 4 1 SusE outer membrane protein EphA2_TM PF14575.6 KFP20050.1 - 0.002 19.0 0.3 0.0047 17.8 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFP20050.1 - 0.0036 17.2 0.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 1 1 TMEM154 protein family DUF4959 PF16323.5 KFP20050.1 - 0.0038 17.5 4.5 1.4 9.3 0.0 3.5 4 0 0 4 4 2 2 Domain of unknown function (DUF4959) Ig_6 PF18452.1 KFP20050.1 - 0.014 15.0 0.0 1.1 8.8 0.0 3.4 4 0 0 4 4 3 0 Immunoglobulin domain Izumo-Ig PF16706.5 KFP20050.1 - 0.016 15.2 0.0 2.6 8.2 0.0 3.9 4 1 0 4 4 4 0 Izumo-like Immunoglobulin domain Ly49 PF08391.10 KFP20050.1 - 0.039 14.3 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Herpes_UL74 PF07982.12 KFP20050.1 - 0.042 12.8 2.1 0.074 12.0 2.1 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins F5_F8_type_C PF00754.25 KFP20050.1 - 0.12 12.5 3.2 2 8.6 0.1 3.5 4 0 0 4 4 3 0 F5/8 type C domain Neur_chan_memb PF02932.16 KFP20050.1 - 0.16 12.0 0.2 0.3 11.1 0.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.6 KFP20050.1 - 0.18 12.0 2.5 0.28 11.4 0.0 2.4 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator FAM176 PF14851.6 KFP20050.1 - 0.22 11.2 0.0 0.52 10.0 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Insulin_TMD PF17870.1 KFP20050.1 - 1.1 9.4 4.3 2.8 8.1 4.3 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ion_trans PF00520.31 KFP20051.1 - 5.1e-23 81.6 15.0 7.1e-23 81.1 15.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.10 KFP20051.1 - 3.1e-20 71.5 0.1 6.8e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal cNMP_binding PF00027.29 KFP20051.1 - 2.7e-18 65.8 0.0 5.6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KFP20051.1 - 0.005 16.8 0.2 0.011 15.6 0.2 1.6 1 0 0 1 1 1 1 Ion channel REC114-like PF15165.6 KFP20052.1 - 3.2e-90 302.1 1.8 3.7e-89 298.6 1.8 1.9 1 1 0 1 1 1 1 Meiotic recombination protein REC114-like Ig_3 PF13927.6 KFP20053.1 - 5.8e-22 78.1 3.4 8.7e-12 45.5 0.2 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP20053.1 - 6.6e-17 61.4 0.1 5e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP20053.1 - 6.5e-11 42.4 4.7 1.4e-05 25.4 0.5 2.2 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP20053.1 - 3.3e-10 40.0 1.2 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP20053.1 - 0.00012 22.3 2.8 1.9 8.7 0.5 3.7 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP20053.1 - 0.0013 19.1 0.0 0.51 10.8 0.0 2.4 2 0 0 2 2 2 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP20053.1 - 0.0019 18.4 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KFP20053.1 - 0.0027 17.2 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP20054.1 - 1.1e-13 51.6 0.0 6e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP20054.1 - 1.7e-12 47.4 0.0 3.1e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP20054.1 - 2.2e-09 37.3 0.1 0.00094 19.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP20054.1 - 2.4e-09 37.4 0.2 3.9e-05 23.9 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP20054.1 - 8.6e-09 35.5 0.1 5.8e-08 32.9 0.0 2.2 2 1 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP20054.1 - 2.3e-06 27.6 0.2 2.3e-05 24.4 0.1 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP20054.1 - 2.8e-06 27.6 0.0 2.1e-05 24.8 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Marek_A PF02124.15 KFP20054.1 - 0.012 15.5 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF2371 PF10177.9 KFP20054.1 - 0.022 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Ig_6 PF18452.1 KFP20054.1 - 0.11 12.1 0.2 0.6 9.7 0.0 2.2 3 0 0 3 3 3 0 Immunoglobulin domain Phage_holin_2_4 PF16082.5 KFP20054.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4307 PF14155.6 KFP20054.1 - 0.24 11.2 4.2 8.9 6.2 0.0 3.3 4 1 0 4 4 3 0 Domain of unknown function (DUF4307) Zona_pellucida PF00100.23 KFP20055.1 - 1.3e-47 162.8 0.0 1.5e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.23 KFP20056.1 - 1.2e-44 153.0 0.0 1.4e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SCP2 PF02036.17 KFP20057.1 - 9.1e-17 61.4 0.0 5.3e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 SCP-2 sterol transfer family Band_7 PF01145.25 KFP20057.1 - 1e-13 51.7 0.0 3e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family LRR_8 PF13855.6 KFP20058.1 - 2.4e-20 72.1 8.6 3.7e-11 42.6 1.3 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP20058.1 - 1.8e-10 40.9 13.5 0.00011 22.5 2.6 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP20058.1 - 2.3e-06 27.2 1.2 0.0023 17.4 0.1 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 KFP20058.1 - 5.5e-06 26.4 0.1 9.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP20058.1 - 0.00097 19.4 7.4 1.4 9.7 0.1 4.7 4 1 0 4 4 4 1 Leucine Rich Repeat TPKR_C2 PF16920.5 KFP20058.1 - 0.0067 16.5 1.8 0.0067 16.5 1.8 2.1 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 KFP20058.1 - 0.66 10.2 6.9 1.2 9.4 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 KFP20059.1 - 1.8e-23 82.1 14.5 3.7e-14 52.2 4.8 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KFP20059.1 - 1.9e-12 47.2 21.9 4.5e-07 30.1 2.3 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP20059.1 - 7.2e-07 28.9 0.1 9.5e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KFP20059.1 - 7.4e-05 22.8 10.2 0.84 10.4 0.3 4.6 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 KFP20059.1 - 0.00036 20.5 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) TPKR_C2 PF16920.5 KFP20059.1 - 0.00054 20.0 1.2 0.0012 19.0 0.4 2.0 2 0 0 2 2 2 1 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_6 PF13516.6 KFP20059.1 - 0.032 14.3 0.4 0.032 14.3 0.4 4.1 5 0 0 5 5 5 0 Leucine Rich repeat RBP_receptor PF14752.6 KFP20060.1 - 1.3e-251 836.5 22.6 1.5e-251 836.3 22.6 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor p450 PF00067.22 KFP20062.1 - 1.1e-23 83.7 0.1 1.2e-23 83.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sema PF01403.19 KFP20063.1 - 1.6e-24 86.5 0.0 1.8e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Sema domain ubiquitin PF00240.23 KFP20065.1 - 3.9e-09 36.1 0.0 6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFP20065.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFP20065.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KFP20065.1 - 0.081 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Actin PF00022.19 KFP20066.1 - 5.2e-151 502.9 0.0 1.7e-150 501.2 0.0 1.6 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 KFP20068.1 - 1.5e-46 158.9 0.1 1.9e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20068.1 - 4.9e-22 78.5 0.3 1.6e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Edc3_linker PF16598.5 KFP20069.1 - 1.4e-44 150.7 4.4 2.5e-44 149.8 4.4 1.5 1 0 0 1 1 1 1 Linker region of enhancer of mRNA-decapping protein 3 YjeF_N PF03853.15 KFP20069.1 - 1.6e-19 70.5 0.0 2.5e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KFP20069.1 - 9.9e-16 58.5 0.0 1.8e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.7 KFP20069.1 - 6.2e-10 39.0 0.0 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain DUF5096 PF17019.5 KFP20069.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5096) Synaphin PF05835.12 KFP20070.1 - 1.3e-47 161.6 11.4 1.6e-47 161.4 11.4 1.1 1 0 0 1 1 1 1 Synaphin protein Pkinase PF00069.25 KFP20071.1 - 9e-66 221.9 0.0 1.4e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20071.1 - 4.7e-39 134.2 0.0 6.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KFP20071.1 - 7.5e-30 102.8 13.7 2.1e-17 62.9 2.3 2.9 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Kdo PF06293.14 KFP20071.1 - 1.2e-05 24.8 0.1 2.4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP20071.1 - 0.054 13.1 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KFP20071.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family SCAMP PF04144.13 KFP20072.1 - 4.5e-63 212.7 16.3 5.4e-63 212.4 16.3 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.8 KFP20072.1 - 0.013 14.9 0.4 0.025 14.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PMI_typeI PF01238.21 KFP20073.1 - 1.8e-131 438.8 0.0 2.2e-131 438.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I COX5A PF02284.16 KFP20074.1 - 7e-47 157.7 0.0 7.9e-47 157.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Alba PF01918.21 KFP20075.1 - 5.8e-20 70.9 0.9 7.3e-20 70.6 0.9 1.1 1 0 0 1 1 1 1 Alba STAT2_C PF12188.8 KFP20075.1 - 0.11 12.5 0.5 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal SCAMP PF04144.13 KFP20076.1 - 1.3e-68 230.7 16.4 1.5e-68 230.5 16.4 1.1 1 0 0 1 1 1 1 SCAMP family Flavoprotein PF02441.19 KFP20077.1 - 1.9e-52 177.2 0.0 2.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Form_Nir_trans PF01226.17 KFP20078.1 - 0.011 15.0 0.2 0.94 8.8 0.3 2.0 2 0 0 2 2 2 0 Formate/nitrite transporter COMM_domain PF07258.14 KFP20079.1 - 3.8e-12 46.1 0.0 6.7e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 COMM domain Y_phosphatase PF00102.27 KFP20080.1 - 2e-80 269.8 0.0 2.7e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 KFP20080.1 - 2.4e-30 105.4 0.1 6.4e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP20080.1 - 1e-11 45.1 0.1 2e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 KFP20080.1 - 0.0063 16.3 1.5 0.016 15.0 0.1 2.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP20080.1 - 0.0063 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CRAL_TRIO_N PF03765.15 KFP20080.1 - 0.037 14.2 0.6 0.34 11.1 0.0 2.7 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain PTPlike_phytase PF14566.6 KFP20080.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate BAR_3_WASP_bdg PF10456.9 KFP20081.1 - 2.9e-109 364.1 4.3 3.7e-109 363.7 4.3 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFP20081.1 - 1.4e-20 73.4 4.0 3.2e-20 72.2 1.3 2.3 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 KFP20081.1 - 4.8e-12 45.5 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP20081.1 - 1.6e-10 40.5 0.0 3.8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP20081.1 - 5.5e-08 32.4 0.0 1.7e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 KFP20081.1 - 1.8e-05 24.4 2.9 0.0016 18.0 1.3 3.0 1 1 2 3 3 3 2 Vps5 C terminal like Cadherin_3 PF16184.5 KFP20082.1 - 3.9e-185 603.2 15.2 1e-22 80.2 0.0 14.2 14 0 0 14 14 14 14 Cadherin-like Cadherin_4 PF17803.1 KFP20082.1 - 0.03 15.0 1.5 8.5 7.1 0.0 4.3 4 0 0 4 4 4 0 Bacterial cadherin-like domain LRR_8 PF13855.6 KFP20083.1 - 1.4e-55 184.9 55.6 2.2e-12 46.6 1.7 6.4 1 1 6 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP20083.1 - 1.9e-28 99.0 0.2 3.9e-12 46.2 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP20083.1 - 5e-20 71.3 34.8 0.00019 21.7 2.1 7.3 5 1 2 7 7 7 7 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP20083.1 - 1.5e-14 53.8 0.0 2.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP20083.1 - 5.1e-12 46.2 0.0 1.1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP20083.1 - 3e-08 33.7 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP20083.1 - 1.2e-07 32.0 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KFP20083.1 - 1.4e-06 28.0 14.2 0.00043 19.8 2.8 3.6 2 2 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFP20083.1 - 5.2e-06 26.3 37.4 11 7.1 0.0 11.8 12 1 0 12 12 12 2 Leucine Rich Repeat LRRNT PF01462.18 KFP20083.1 - 0.032 13.9 8.7 0.025 14.3 2.8 3.2 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain V-set PF07686.17 KFP20083.1 - 0.19 11.9 0.0 0.87 9.8 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_6 PF13516.6 KFP20083.1 - 0.42 10.8 36.9 6.4 7.1 0.1 10.0 11 0 0 11 11 11 0 Leucine Rich repeat HMG_box PF00505.19 KFP20086.1 - 9.9e-19 67.5 1.4 9.9e-19 67.5 1.4 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP20086.1 - 1.6e-12 47.8 0.7 1.6e-12 47.8 0.7 2.6 2 1 1 3 3 3 1 HMG-box domain DUF4763 PF15960.5 KFP20086.1 - 0.0028 17.0 3.7 0.0028 17.0 3.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Trans_reg_C PF00486.28 KFP20086.1 - 0.0035 17.4 0.3 0.63 10.2 0.0 3.1 2 1 1 3 3 3 1 Transcriptional regulatory protein, C terminal COG5 PF10392.9 KFP20086.1 - 0.069 13.3 3.9 0.084 13.0 2.3 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Lectin_N PF03954.14 KFP20086.1 - 0.52 10.1 3.9 6.1 6.6 3.9 2.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Pkinase PF00069.25 KFP20087.1 - 1.9e-12 47.1 0.0 4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20087.1 - 4.7e-06 26.1 0.0 9.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP20087.1 - 0.042 13.8 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PTPRCAP PF15713.5 KFP20087.1 - 8.9 6.6 14.5 0.54 10.5 1.6 3.3 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Tetraspanin PF00335.20 KFP20088.1 - 4.8e-44 150.8 11.5 5.5e-44 150.6 11.5 1.0 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 KFP20088.1 - 0.0078 15.9 6.2 0.036 13.7 1.8 2.2 2 0 0 2 2 2 1 SUR7/PalI family COX2_TM PF02790.15 KFP20088.1 - 0.015 15.5 3.5 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1616 PF07760.11 KFP20088.1 - 0.1 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF996 PF06195.13 KFP20088.1 - 0.22 11.8 8.7 0.045 14.0 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Hum_adeno_E3A PF05393.11 KFP20088.1 - 0.29 11.1 3.9 0.7 9.9 0.4 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF2207 PF09972.9 KFP20088.1 - 4.4 5.9 5.0 1.6 7.4 1.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ECSCR PF15820.5 KFP20088.1 - 7.8 6.4 7.0 1.3 8.9 2.5 1.9 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator SH3_9 PF14604.6 KFP20089.1 - 2.6e-17 62.4 0.4 6e-17 61.3 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFP20089.1 - 8.2e-17 60.5 0.2 1.6e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 KFP20089.1 - 4e-14 52.7 0.3 4e-14 52.7 0.3 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 KFP20089.1 - 2e-12 46.6 0.0 4.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KFP20089.1 - 0.0032 17.7 0.4 0.0057 16.9 0.4 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain ALMT PF11744.8 KFP20089.1 - 4 6.2 14.1 5.3 5.8 14.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter BCL_N PF04714.13 KFP20089.1 - 4.7 7.4 5.8 8.9 6.5 0.2 2.8 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Presenilin PF01080.17 KFP20089.1 - 9.6 4.9 11.5 14 4.4 11.5 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KFP20089.1 - 9.8 6.2 9.2 17 5.4 9.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.32 KFP20091.1 - 8.1e-17 59.4 13.7 2.1e-05 23.7 0.2 5.3 5 1 1 6 6 6 4 EF hand EF-hand_7 PF13499.6 KFP20091.1 - 1.5e-15 57.4 14.0 1.2e-06 28.9 0.4 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFP20091.1 - 4.9e-15 54.1 6.4 0.0015 18.3 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KFP20091.1 - 1.2e-13 49.8 4.3 0.0022 17.4 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KFP20091.1 - 1.5e-06 27.9 11.4 0.023 14.5 0.3 4.6 4 1 1 5 5 5 3 EF-hand domain pair SCAPER_N PF16501.5 KFP20092.1 - 3.5e-44 148.8 0.3 3.5e-44 148.8 0.3 3.0 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 KFP20092.1 - 6.1e-07 29.6 1.7 2.1e-06 27.9 1.7 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP20092.1 - 0.0086 16.3 0.9 0.034 14.5 0.9 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF5487 PF17589.2 KFP20092.1 - 0.17 12.2 0.1 0.39 11.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) ETF PF01012.21 KFP20093.1 - 9.3e-42 143.0 0.2 1.3e-41 142.5 0.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFP20093.1 - 5.9e-38 128.8 1.3 1.1e-37 128.0 0.3 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ion_trans PF00520.31 KFP20094.1 - 1.5e-07 30.9 7.3 2.2e-07 30.4 7.3 1.2 1 0 0 1 1 1 1 Ion transport protein zf-C4H2 PF10146.9 KFP20094.1 - 0.23 11.7 2.3 0.39 11.0 2.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein EGF PF00008.27 KFP20095.1 - 0.0011 19.3 5.9 0.0016 18.7 5.9 1.3 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 KFP20095.1 - 0.012 16.0 3.1 0.012 16.0 3.1 2.0 2 1 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 KFP20095.1 - 1.5 9.0 6.1 0.21 11.8 2.3 1.6 2 0 0 2 2 2 0 Laminin EGF domain FIST_C PF10442.9 KFP20097.1 - 2.7e-12 46.8 0.0 5.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 KFP20097.1 - 3.3e-05 24.0 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 2 FIST N domain Toprim_3 PF13362.6 KFP20097.1 - 0.045 14.1 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 Toprim domain UQ_con PF00179.26 KFP20098.1 - 5.6e-11 42.3 0.0 6.2e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP20098.1 - 0.0053 16.5 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B Josephin PF02099.17 KFP20098.1 - 0.046 13.8 0.1 0.066 13.3 0.0 1.4 1 1 0 1 1 1 0 Josephin TraC_F_IV PF11130.8 KFP20098.1 - 0.12 12.0 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer TPR_MLP1_2 PF07926.12 KFP20098.1 - 0.53 10.4 4.2 0.57 10.3 0.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein KIAA1430 PF13879.6 KFP20098.1 - 7.7 7.3 9.9 3.1 8.6 0.7 2.9 2 1 1 3 3 3 0 KIAA1430 homologue RVT_1 PF00078.27 KFP20099.1 - 0.00082 18.9 0.0 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_LBD PF02931.23 KFP20101.1 - 2.6e-72 242.8 0.5 3.4e-72 242.4 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP20101.1 - 5.1e-65 219.9 14.3 9.4e-51 173.2 9.4 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.26 KFP20102.1 - 2.4e-55 187.0 0.0 3e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFP20102.1 - 8e-14 51.0 0.1 1.3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TRP_N PF14558.6 KFP20102.1 - 0.1 12.9 0.1 0.55 10.6 0.0 1.9 2 0 0 2 2 2 0 ML-like domain Phenol_monoox PF04663.12 KFP20102.1 - 0.12 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Phenol hydroxylase conserved region APH PF01636.23 KFP20103.1 - 9.4e-23 81.4 0.0 1.2e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP20103.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KFP20103.1 - 0.041 13.2 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Aconitase PF00330.20 KFP20104.1 - 1.1e-154 515.9 0.0 1.4e-154 515.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFP20104.1 - 6.2e-41 139.8 0.0 1e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Lipocalin PF00061.23 KFP20105.1 - 5.9e-17 62.2 0.3 6.4e-17 62.1 0.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family WD40 PF00400.32 KFP20106.1 - 1.4e-42 142.9 24.8 1.9e-09 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP20106.1 - 2.4e-24 85.4 2.0 8.2e-06 26.0 0.0 6.4 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP20106.1 - 1.8e-08 33.7 3.7 0.022 13.7 0.0 4.8 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFP20106.1 - 2.1e-06 26.5 1.9 0.78 8.2 0.0 3.7 1 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 KFP20106.1 - 9.4e-06 24.5 0.1 0.017 13.8 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 KFP20106.1 - 0.00011 22.0 0.1 1.4 9.0 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat HPS3_N PF14761.6 KFP20106.1 - 0.00037 20.1 0.0 0.14 11.7 0.0 3.0 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 KFP20106.1 - 0.00078 18.9 0.1 0.5 9.6 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain GSDH PF07995.11 KFP20106.1 - 0.0046 16.3 0.0 0.42 9.9 0.0 2.4 1 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Frtz PF11768.8 KFP20106.1 - 0.0046 15.3 0.0 0.016 13.5 0.0 1.8 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF2415 PF10313.9 KFP20106.1 - 0.028 14.4 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) PQQ PF01011.21 KFP20106.1 - 0.029 14.3 2.8 7.2 6.7 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 KFP20106.1 - 0.049 12.5 0.7 3.6 6.4 0.1 2.9 2 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DnaJ_C PF01556.18 KFP20107.1 - 6.5e-45 152.8 0.8 8.2e-45 152.5 0.8 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KFP20107.1 - 9.4e-15 54.7 19.1 1.8e-14 53.9 19.1 1.5 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KFP20107.1 - 3.8e-05 23.7 0.1 6.4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Anti-TRAP PF15777.5 KFP20107.1 - 0.0086 16.0 11.8 0.17 11.9 1.3 2.7 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KFP20107.1 - 0.12 12.1 7.4 0.98 9.1 2.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 KFP20107.1 - 0.2 11.7 8.1 3.8 7.6 0.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KFP20107.1 - 0.24 11.6 10.1 0.19 11.9 6.6 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf_CopZ PF18423.1 KFP20107.1 - 0.28 11.2 4.6 9.4 6.3 0.3 2.6 2 0 0 2 2 2 0 Zinc binding domain PADR1 PF08063.12 KFP20107.1 - 0.76 9.6 8.5 0.92 9.3 0.1 3.4 3 0 0 3 3 3 0 PADR1 (NUC008) domain RseC_MucC PF04246.12 KFP20107.1 - 0.92 9.5 5.6 0.095 12.6 0.8 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AMP-binding PF00501.28 KFP20108.1 - 1.2e-90 304.1 0.0 1.4e-90 303.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Iso_dh PF00180.20 KFP20109.1 - 6.7e-112 374.1 0.0 7.7e-112 373.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_7 PF13499.6 KFP20110.1 - 2.6e-12 47.0 2.7 5.7e-10 39.5 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP20110.1 - 3.7e-08 32.4 10.5 9e-05 21.7 0.5 3.5 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KFP20110.1 - 8e-08 31.6 7.4 0.0042 16.9 0.4 3.6 2 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KFP20110.1 - 0.00011 22.0 8.1 0.01 15.6 1.9 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP20110.1 - 0.0017 17.7 8.3 0.041 13.4 0.8 3.7 3 1 1 4 4 4 2 EF hand PMBR PF09373.10 KFP20110.1 - 0.043 14.0 0.0 16 5.9 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat Dockerin_1 PF00404.18 KFP20110.1 - 0.14 12.3 0.1 0.36 11.1 0.1 1.7 1 1 0 1 1 1 0 Dockerin type I domain DUF3349 PF11829.8 KFP20110.1 - 0.18 12.6 0.0 0.24 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) RabGAP-TBC PF00566.18 KFP20113.1 - 1.9e-57 194.4 3.6 1.9e-57 194.4 3.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain KRAB PF01352.27 KFP20113.1 - 0.0046 16.6 0.3 0.025 14.2 0.1 2.4 2 0 0 2 2 2 1 KRAB box DUF1664 PF07889.12 KFP20113.1 - 0.08 13.0 13.7 0.088 12.8 1.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 KFP20113.1 - 1.7 7.9 17.5 2.3 7.5 15.8 2.2 1 1 1 2 2 2 0 FAM76 protein DivIC PF04977.15 KFP20113.1 - 3.2 7.6 26.7 0.38 10.5 5.9 4.3 3 1 1 4 4 4 0 Septum formation initiator Spc7 PF08317.11 KFP20113.1 - 3.5 6.4 26.6 2 7.2 14.9 2.7 1 1 0 2 2 2 0 Spc7 kinetochore protein LRR_6 PF13516.6 KFP20115.1 - 0.0071 16.3 2.8 5.6 7.3 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat F-box-like PF12937.7 KFP20115.1 - 0.0071 16.2 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KFP20115.1 - 0.07 13.6 7.9 0.24 11.9 3.8 3.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) UCH PF00443.29 KFP20116.1 - 1.6e-62 211.3 0.3 2.6e-62 210.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP20116.1 - 3.8e-22 79.3 5.3 2.6e-21 76.6 0.1 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP20116.1 - 3.1e-19 69.1 11.4 3.1e-19 69.1 11.4 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-AD PF07776.15 KFP20116.1 - 5.8 7.2 14.2 2 8.7 3.4 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Carb_anhydrase PF00194.21 KFP20117.1 - 6.1e-87 291.4 0.0 6.8e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.22 KFP20118.1 - 3.7e-51 172.9 0.4 4.6e-51 172.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20118.1 - 4.4e-22 78.5 0.1 8.3e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20118.1 - 1.2e-11 44.4 0.4 1.4e-11 44.2 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP20118.1 - 0.00022 20.8 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3963 PF13124.6 KFP20118.1 - 0.018 15.0 0.8 0.034 14.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Gtr1_RagA PF04670.12 KFP20118.1 - 0.031 13.6 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S27e PF01667.17 KFP20119.1 - 3.8e-30 103.4 4.8 4.6e-30 103.1 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Beta-lactamase PF00144.24 KFP20120.1 - 1.5e-52 178.9 0.0 9.6e-28 97.4 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.20 KFP20120.1 - 0.02 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase GDI PF00996.18 KFP20120.1 - 0.038 12.5 1.1 0.054 12.0 1.1 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Beta-lactamase2 PF13354.6 KFP20120.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family B12D PF06522.11 KFP20120.1 - 0.96 9.3 3.7 0.59 10.0 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Tropomyosin PF00261.20 KFP20121.1 - 3.6e-103 344.0 85.4 7.5e-99 329.9 61.8 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP20121.1 - 1e-39 136.0 74.6 1.4e-35 122.5 41.9 3.0 1 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 KFP20121.1 - 4.2e-07 30.1 36.9 2.4e-05 24.4 7.1 3.9 1 1 3 4 4 4 3 Laminin Domain II CLZ PF16526.5 KFP20121.1 - 1.1e-06 28.9 50.5 2e-05 24.8 10.7 5.0 1 1 3 5 5 5 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 KFP20121.1 - 0.00066 19.6 9.3 0.00066 19.6 9.3 6.3 2 2 4 6 6 6 2 TATA element modulatory factor 1 DNA binding DUF745 PF05335.13 KFP20121.1 - 0.0036 17.1 47.1 0.17 11.6 9.2 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF745) ERM PF00769.19 KFP20121.1 - 0.0042 16.9 71.8 0.2 11.5 25.8 2.8 1 1 1 2 2 2 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KFP20121.1 - 0.0046 17.0 30.8 0.0046 17.0 30.8 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.14 KFP20121.1 - 0.0096 15.6 53.3 0.13 11.9 15.6 3.1 1 1 2 3 3 3 2 Laminin Domain I XhlA PF10779.9 KFP20121.1 - 0.019 15.1 3.7 0.019 15.1 3.7 6.8 2 2 4 7 7 7 0 Haemolysin XhlA ATG16 PF08614.11 KFP20121.1 - 0.023 14.9 60.5 0.18 12.0 20.8 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 KFP20121.1 - 0.038 13.5 50.9 0.67 9.5 6.7 3.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 KFP20121.1 - 0.053 12.2 49.1 0.18 10.4 32.6 2.1 1 1 1 2 2 2 0 AAA domain Golgin_A5 PF09787.9 KFP20121.1 - 0.084 12.3 55.9 0.46 9.9 21.3 2.8 1 1 2 3 3 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 KFP20121.1 - 0.12 12.4 31.8 0.16 12.0 2.9 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) GAS PF13851.6 KFP20121.1 - 0.17 11.2 62.9 0.29 10.5 16.3 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KFP20121.1 - 0.28 11.3 50.9 2.1 8.4 8.0 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KFP20121.1 - 0.33 11.5 39.8 0.48 10.9 0.4 4.5 1 1 3 4 4 4 0 Protein of unknown function DUF16 Lebercilin PF15619.6 KFP20121.1 - 0.34 10.5 61.9 0.073 12.7 17.8 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF1794 PF08768.11 KFP20121.1 - 0.37 10.7 4.9 7.7 6.4 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1794) SNARE PF05739.19 KFP20121.1 - 0.43 10.6 9.7 2.3 8.3 0.1 4.5 5 0 0 5 5 4 0 SNARE domain SlyX PF04102.12 KFP20121.1 - 0.47 11.1 44.5 0.35 11.5 3.5 5.3 1 1 4 5 5 4 0 SlyX T3SSipB PF16535.5 KFP20121.1 - 0.47 10.9 45.4 4.2 7.8 3.1 4.4 1 1 3 4 4 4 0 Type III cell invasion protein SipB MAD PF05557.13 KFP20121.1 - 0.57 8.5 59.3 1.5 7.1 23.3 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Fib_alpha PF08702.10 KFP20121.1 - 0.61 10.3 33.2 0.13 12.5 6.8 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KFP20121.1 - 1 6.8 57.2 0.82 7.1 22.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 KFP20121.1 - 1.2 8.7 36.1 12 5.3 14.3 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Flagellin_C PF00700.21 KFP20121.1 - 1.7 9.1 13.0 0.59 10.5 1.8 3.9 1 1 3 4 4 4 0 Bacterial flagellin C-terminal helical region TTKRSYEDQ PF10212.9 KFP20121.1 - 1.7 7.5 37.4 0.093 11.7 11.6 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein EzrA PF06160.12 KFP20121.1 - 1.9 6.6 55.3 0.082 11.1 11.0 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF4200 PF13863.6 KFP20121.1 - 2 8.9 71.1 0.14 12.6 10.9 4.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) Fmp27_WPPW PF10359.9 KFP20121.1 - 2.4 6.9 39.8 0.43 9.4 10.6 2.8 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain HOOK PF05622.12 KFP20121.1 - 2.6 6.1 58.9 0.021 13.0 16.2 2.1 1 1 1 2 2 2 0 HOOK protein DUF4472 PF14739.6 KFP20121.1 - 3.5 8.4 52.8 0.63 10.8 3.1 4.6 1 1 4 5 5 4 0 Domain of unknown function (DUF4472) FH2 PF02181.23 KFP20121.1 - 3.9 6.5 38.0 0.64 9.1 9.5 3.1 1 1 2 3 3 3 0 Formin Homology 2 Domain FPP PF05911.11 KFP20121.1 - 4.5 5.3 60.8 1.7 6.8 16.8 2.8 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil COG2 PF06148.11 KFP20121.1 - 5.4 7.1 31.8 0.069 13.2 1.2 4.1 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KFP20121.1 - 5.5 7.5 19.4 12 6.5 0.8 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 KFP20121.1 - 5.6 7.4 53.2 1.3 9.4 13.7 3.2 1 1 1 2 2 1 0 Fez1 FlaC_arch PF05377.11 KFP20121.1 - 7.5 7.0 32.1 1.7 9.1 2.8 5.5 2 2 4 6 6 6 0 Flagella accessory protein C (FlaC) Uds1 PF15456.6 KFP20121.1 - 7.5 6.7 48.9 12 6.0 6.8 4.6 1 1 2 4 4 4 0 Up-regulated During Septation I_LWEQ PF01608.17 KFP20122.1 - 4.9e-65 218.4 200.6 2.5e-48 164.2 15.4 19.3 9 4 7 18 18 18 9 I/LWEQ domain VBS PF08913.10 KFP20122.1 - 8.8e-65 216.8 110.7 2.6e-64 215.3 0.5 12.6 12 2 2 14 14 14 6 Vinculin Binding Site Talin_middle PF09141.10 KFP20122.1 - 6.2e-55 185.6 4.0 6.2e-55 185.6 4.0 15.4 9 6 7 16 16 16 3 Talin, middle domain FERM_f0 PF16511.5 KFP20122.1 - 5.9e-38 129.0 0.1 8.2e-35 119.0 0.0 3.3 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 KFP20122.1 - 4.5e-27 94.8 0.0 3.1e-26 92.1 0.0 2.6 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP20122.1 - 1.4e-23 82.6 2.7 1.2e-21 76.4 0.7 3.3 3 0 0 3 3 3 1 FERM N-terminal domain IRS PF02174.17 KFP20122.1 - 0.00077 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ACBP PF00887.19 KFP20122.1 - 0.0012 19.1 0.1 0.019 15.2 0.0 2.9 2 0 0 2 2 2 1 Acyl CoA binding protein DUF2605 PF10792.9 KFP20122.1 - 0.028 14.3 0.5 0.55 10.2 0.5 3.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) ubiquitin PF00240.23 KFP20122.1 - 0.075 12.8 0.2 26 4.6 0.0 3.7 3 0 0 3 3 3 0 Ubiquitin family C2 PF00168.30 KFP20126.1 - 2.8e-07 30.8 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain VPS13_mid_rpt PF16910.5 KFP20127.1 - 2.1e-87 292.4 27.1 8e-68 228.4 1.5 7.1 5 2 0 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KFP20127.1 - 6.8e-69 232.3 9.7 7.1e-66 222.4 2.7 4.7 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KFP20127.1 - 4.5e-65 218.8 7.0 4.3e-62 209.0 0.2 3.5 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KFP20127.1 - 5.6e-33 114.5 0.1 1.8e-30 106.3 0.1 3.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KFP20127.1 - 1.4e-22 79.9 0.2 1.5e-21 76.7 0.2 3.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KFP20127.1 - 9.7e-10 38.7 1.5 2.5e-09 37.3 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain WWE PF02825.20 KFP20127.1 - 0.0081 16.7 0.1 0.045 14.4 0.1 2.4 1 0 0 1 1 1 1 WWE domain zf-C4 PF00105.18 KFP20132.1 - 4.2e-33 113.6 12.9 4.2e-33 113.6 12.9 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP20132.1 - 3.1e-24 85.7 4.5 3.1e-24 85.7 4.5 1.9 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor NARG2_C PF10505.9 KFP20133.1 - 4.6e-78 261.5 0.7 8.9e-78 260.6 0.7 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus NVEALA PF14055.6 KFP20133.1 - 0.58 10.2 2.1 0.78 9.8 0.7 1.9 2 0 0 2 2 2 0 NVEALA protein Annexin PF00191.20 KFP20134.1 - 2.4e-94 309.4 10.6 1.3e-26 92.5 0.5 4.1 4 0 0 4 4 4 4 Annexin BNIP2 PF12496.8 KFP20137.1 - 7.1e-35 120.4 1.8 7.1e-35 120.4 1.8 1.5 2 0 0 2 2 2 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.6 KFP20137.1 - 7.8e-30 103.8 0.3 1.1e-29 103.4 0.3 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFP20137.1 - 1.3e-08 34.8 0.1 1.8e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TFIIA_gamma_N PF02268.16 KFP20138.1 - 7.9e-24 83.4 0.4 1.1e-23 82.9 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KFP20138.1 - 1.7e-22 79.2 2.7 2.5e-22 78.7 2.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit RVT_1 PF00078.27 KFP20140.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OTU PF02338.19 KFP20141.1 - 5.7e-24 85.0 0.0 1.3e-23 83.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.6 KFP20141.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFP20141.1 - 0.0046 16.6 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain zf-C2H2 PF00096.26 KFP20142.1 - 8.4e-15 54.3 23.5 2.6e-05 24.4 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP20142.1 - 1.9e-13 50.1 11.0 1.3e-07 31.7 1.5 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP20142.1 - 3.6e-08 33.6 21.5 0.0025 18.5 2.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP20142.1 - 0.0058 17.2 9.4 1.2 9.9 0.5 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 KFP20142.1 - 0.034 14.5 10.7 1.4 9.4 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP20142.1 - 0.31 11.4 5.0 0.1 12.9 1.7 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KFP20142.1 - 2.3 8.6 19.5 3 8.2 0.3 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KFP20142.1 - 5.9 7.0 10.1 29 4.8 7.6 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger LSDAT_euk PF18139.1 KFP20144.1 - 1.8e-122 407.8 0.0 2.6e-122 407.3 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM TRPM_tetra PF16519.5 KFP20144.1 - 2.3e-24 85.2 5.8 2.3e-24 85.2 5.8 1.9 2 0 0 2 2 2 1 Tetramerisation domain of TRPM Ion_trans PF00520.31 KFP20144.1 - 6.1e-20 71.5 16.0 1e-19 70.8 16.0 1.3 1 0 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 KFP20144.1 - 3.9e-17 62.2 0.1 7.5e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Glutaredoxin2_C PF04399.13 KFP20144.1 - 0.3 10.9 1.2 0.71 9.7 1.2 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Myotub-related PF06602.14 KFP20146.1 - 2.2e-69 234.1 6.5 2.6e-57 194.3 3.1 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 KFP20146.1 - 2.4e-58 195.5 0.2 4.3e-58 194.8 0.2 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein VRR_NUC PF08774.11 KFP20147.1 - 4.2e-25 87.9 0.0 1e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain TPR_12 PF13424.6 KFP20147.1 - 0.19 12.1 3.4 9 6.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-WRNIP1_ubi PF18279.1 KFP20147.1 - 1.1 10.0 3.6 0.57 10.9 0.2 2.4 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Mpp10 PF04006.12 KFP20148.1 - 3.9e-199 663.1 83.9 4.9e-199 662.8 83.9 1.1 1 0 0 1 1 1 1 Mpp10 protein Glyoxalase_4 PF13669.6 KFP20149.1 - 2.4e-22 79.3 0.0 2.9e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KFP20149.1 - 8.8e-12 45.3 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFP20149.1 - 2.1e-08 34.5 0.0 2.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFP20149.1 - 0.00028 20.8 0.0 0.00052 19.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain DUF1338 PF07063.13 KFP20149.1 - 0.065 12.4 0.0 1.2 8.2 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1338) Glyoxalase_6 PF18029.1 KFP20149.1 - 0.21 12.4 0.0 0.31 11.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Myco_arth_vir_N PF09610.10 KFP20149.1 - 1.3 9.2 4.5 0.54 10.4 1.6 1.8 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) PID PF00640.23 KFP20152.1 - 1.6e-51 174.0 2.3 1.6e-51 174.0 2.3 2.4 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KFP20152.1 - 5.1e-27 94.1 10.9 1.7e-13 50.7 0.9 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFP20152.1 - 3.3e-15 55.6 2.3 9.6e-08 31.8 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP20152.1 - 1.2e-05 25.5 0.1 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 PDZ domain NRho PF16733.5 KFP20152.1 - 0.08 13.0 1.4 0.21 11.7 0.1 2.4 3 0 0 3 3 3 0 Rhomboid N-terminal domain CD20 PF04103.15 KFP20153.1 - 3.7e-12 46.6 11.6 7.3e-12 45.6 11.6 1.5 1 0 0 1 1 1 1 CD20-like family tRNA-synt_2b PF00587.25 KFP20154.1 - 1.6e-35 122.7 0.0 2.6e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFP20154.1 - 3.6e-21 75.1 0.1 9.5e-21 73.8 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KFP20154.1 - 2.5e-13 49.9 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KFP20154.1 - 5.5e-13 48.8 0.1 1.4e-12 47.5 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TM2 PF05154.16 KFP20155.1 - 8.6e-15 54.8 7.9 1.4e-14 54.1 7.9 1.3 1 0 0 1 1 1 1 TM2 domain zf-RING-like PF08746.11 KFP20155.1 - 9.1 6.7 24.1 12 6.3 8.3 3.6 2 2 0 2 2 2 0 RING-like domain A_deaminase PF00962.22 KFP20156.1 - 1e-36 126.9 0.0 1.2e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFP20156.1 - 0.0095 15.3 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family LRR_9 PF14580.6 KFP20157.1 - 1.5e-24 86.4 17.1 6.8e-15 55.0 4.5 3.9 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 KFP20157.1 - 1.9e-22 78.9 39.4 1.6e-08 34.7 5.2 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP20157.1 - 1.8e-13 50.0 43.8 3.4e-07 29.9 10.8 6.3 5 1 3 8 8 8 5 Leucine rich repeat DUF2322 PF10084.9 KFP20157.1 - 0.73 9.9 3.8 8.4 6.5 0.3 3.6 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_3 PF07725.12 KFP20157.1 - 0.89 9.5 6.2 42 4.2 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat ADAM_spacer1 PF05986.14 KFP20161.1 - 1.5e-36 124.9 0.0 2.1e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP20161.1 - 4.7e-27 94.0 72.2 7.7e-08 32.4 4.9 7.0 5 1 1 6 6 6 6 Thrombospondin type 1 domain PLAC PF08686.11 KFP20161.1 - 4.2e-10 40.2 14.9 2.3e-09 37.8 14.9 2.5 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Neur_chan_LBD PF02931.23 KFP20163.1 - 1.2e-73 247.1 1.1 1.6e-73 246.8 1.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP20163.1 - 1.4e-65 221.7 0.0 1.7e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SUR7 PF06687.12 KFP20163.1 - 0.098 12.3 0.0 0.098 12.3 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF2417 PF10329.9 KFP20163.1 - 1.4 8.3 5.0 1 8.7 2.7 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) tRNA_bind_3 PF17176.4 KFP20165.1 - 0.014 15.7 2.9 0.024 14.9 0.1 2.8 2 1 0 3 3 3 0 tRNA-binding domain Apolipoprotein PF01442.18 KFP20165.1 - 0.18 11.6 30.1 0.49 10.2 21.0 2.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KFP20165.1 - 0.79 9.8 22.4 1 9.4 1.1 4.2 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GLE1 PF07817.13 KFP20165.1 - 1.6 7.9 19.1 0.037 13.2 4.9 3.6 3 1 1 4 4 4 0 GLE1-like protein Fib_alpha PF08702.10 KFP20165.1 - 3 8.0 35.9 1.4 9.1 0.4 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myosin_head PF00063.21 KFP20167.1 - 1.9e-252 839.4 5.7 2.5e-252 839.0 5.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFP20167.1 - 2.9e-55 186.9 1.7 5.8e-55 185.9 1.7 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KFP20167.1 - 4.9e-17 61.3 0.3 1.8e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP20167.1 - 1.4e-15 56.9 0.1 3.9e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP20167.1 - 6.5e-12 44.9 0.0 1.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KFP20167.1 - 0.0068 16.8 0.0 0.042 14.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain IQ PF00612.27 KFP20167.1 - 0.0077 15.9 2.2 0.024 14.4 2.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP20167.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 KFP20167.1 - 0.057 13.4 0.3 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Sigma54_activat PF00158.26 KFP20167.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KFP20167.1 - 0.16 12.5 0.2 0.62 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Cyclin_N PF00134.23 KFP20168.1 - 2.7e-42 143.5 2.0 9.8e-41 138.5 0.3 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP20168.1 - 7.4e-36 122.8 2.0 2.2e-35 121.3 0.7 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNF111_N PF15303.6 KFP20169.1 - 1.7e-126 421.7 26.7 1.7e-126 421.7 26.7 2.4 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.6 KFP20169.1 - 7.6e-13 48.6 6.8 7.6e-13 48.6 6.8 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP20169.1 - 4.5e-09 36.0 6.6 4.5e-09 36.0 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP20169.1 - 8.2e-08 31.9 2.6 8.2e-08 31.9 2.6 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 KFP20169.1 - 3.6e-07 30.4 4.1 3.6e-07 30.4 4.1 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP20169.1 - 9.6e-07 28.6 4.5 2.5e-06 27.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP20169.1 - 1.8e-06 27.7 5.9 1.8e-06 27.7 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP20169.1 - 3.3e-05 23.8 3.8 3.3e-05 23.8 3.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP20169.1 - 0.00029 20.6 4.6 0.00029 20.6 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP20169.1 - 0.068 13.2 5.8 0.14 12.2 3.9 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP20169.1 - 0.1 12.2 6.1 0.068 12.8 3.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KFP20169.1 - 0.57 10.3 6.6 2.2 8.5 6.5 2.2 1 1 0 1 1 1 0 RING-variant domain RRM_1 PF00076.22 KFP20170.1 - 2.4e-11 43.3 0.0 4.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP20170.1 - 3.7e-08 33.0 0.0 8.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MINDY_DUB PF04424.13 KFP20171.1 - 1.8e-37 128.0 1.9 3e-37 127.2 0.1 2.0 2 0 0 2 2 2 1 MINDY deubiquitinase gpW PF02831.15 KFP20171.1 - 0.058 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 gpW Phage_ABA_S PF18066.1 KFP20171.1 - 0.14 12.9 0.1 0.47 11.2 0.0 1.9 2 0 0 2 2 2 0 Phage ABA sandwich domain CCDC50_N PF15295.6 KFP20171.1 - 0.17 12.0 14.0 0.45 10.7 14.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Ribosomal_60s PF00428.19 KFP20171.1 - 9 7.0 6.9 21 5.8 6.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Reprolysin_2 PF13574.6 KFP20172.1 - 4.9e-34 117.9 0.2 4.9e-34 117.9 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFP20172.1 - 1.3e-32 113.6 1.7 1.7e-31 109.9 0.2 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP20172.1 - 1.2e-27 96.9 0.0 2.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP20172.1 - 5.7e-16 58.8 0.3 1.1e-15 57.8 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFP20172.1 - 7.2e-14 52.3 31.8 7.2e-14 52.3 31.8 3.7 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.19 KFP20172.1 - 2e-12 47.5 0.8 4e-12 46.5 0.8 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFP20172.1 - 1.3e-07 31.7 1.1 1.2e-05 25.3 1.1 2.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.6 KFP20172.1 - 0.023 14.7 0.3 0.055 13.5 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Peptidase_M66 PF10462.9 KFP20172.1 - 0.024 13.6 0.2 0.048 12.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 Lipase PF00151.19 KFP20173.1 - 7.6e-121 403.5 0.1 8.9e-121 403.3 0.1 1.0 1 0 0 1 1 1 1 Lipase PLAT PF01477.23 KFP20173.1 - 1.1e-18 67.9 1.4 2.2e-18 66.9 1.4 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.7 KFP20173.1 - 7.2e-06 26.8 0.3 9.6e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP20173.1 - 0.0018 17.9 0.1 0.0027 17.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MIP PF00230.20 KFP20176.1 - 2.9e-51 174.4 14.0 3.7e-51 174.0 14.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Aldedh PF00171.22 KFP20177.1 - 3.8e-179 596.0 0.0 4.3e-179 595.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFP20177.1 - 0.014 14.9 0.1 4 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.14 KFP20177.1 - 0.18 10.8 0.0 11 4.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) SlyX PF04102.12 KFP20179.1 - 0.00095 19.7 2.8 0.00095 19.7 2.8 6.9 3 2 4 7 7 7 1 SlyX BLOC1_2 PF10046.9 KFP20179.1 - 0.0087 16.3 4.6 0.0087 16.3 4.6 5.0 2 1 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 KFP20179.1 - 1.9 7.8 31.7 0.089 12.2 12.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) ATG16 PF08614.11 KFP20179.1 - 1.9 8.6 60.3 3 8.0 13.0 3.8 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PUMA PF15826.5 KFP20179.1 - 2 8.5 4.7 0.43 10.7 0.5 1.9 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Myosin_tail_1 PF01576.19 KFP20180.1 - 2.6e-54 184.5 179.2 3.4e-35 121.2 52.8 2.3 1 1 1 2 2 2 2 Myosin tail CALCOCO1 PF07888.11 KFP20180.1 - 0.003 16.5 45.0 0.003 16.5 45.0 4.5 1 1 3 4 4 4 1 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 KFP20180.1 - 0.0048 17.0 5.1 0.0048 17.0 5.1 13.1 5 3 9 14 14 14 2 bZIP transcription factor Filament PF00038.21 KFP20180.1 - 0.0064 16.1 158.2 0.18 11.4 26.3 6.5 1 1 3 5 5 5 4 Intermediate filament protein CinA_KH PF18146.1 KFP20180.1 - 8.3 6.6 18.1 0.047 13.8 0.5 4.6 3 2 0 4 4 4 0 Damage-inducible protein CinA KH domain HLH PF00010.26 KFP20182.1 - 1.3e-10 41.1 1.2 1.3e-09 37.9 1.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 KFP20182.1 - 4.4 5.5 9.1 5.7 5.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4195 PF13836.6 KFP20183.1 - 8.3e-52 176.0 17.1 8.3e-52 176.0 17.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4195) zf-C2H2_6 PF13912.6 KFP20183.1 - 0.0012 18.8 0.1 0.0012 18.8 0.1 7.7 7 1 0 7 7 7 1 C2H2-type zinc finger zf-Di19 PF05605.12 KFP20183.1 - 0.0017 18.6 2.0 0.0017 18.6 2.0 7.3 6 2 1 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFP20183.1 - 0.011 16.2 0.2 0.011 16.2 0.2 9.9 9 2 1 10 10 10 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP20183.1 - 0.019 15.2 0.3 0.019 15.2 0.3 7.3 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP20183.1 - 0.076 13.9 80.7 0.094 13.6 0.2 9.4 10 0 0 10 10 10 0 C2H2-type zinc finger zf-met PF12874.7 KFP20183.1 - 0.13 12.7 0.2 0.13 12.7 0.2 6.6 6 1 0 6 6 6 0 Zinc-finger of C2H2 type TPH PF13868.6 KFP20184.1 - 7.5e-83 277.9 155.0 7.5e-83 277.9 155.0 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DpnD-PcfM PF14207.6 KFP20185.1 - 0.013 15.3 0.2 0.29 11.0 0.0 2.8 2 0 0 2 2 2 0 DpnD/PcfM-like protein PRKG1_interact PF15898.5 KFP20185.1 - 0.038 14.9 20.1 0.038 14.9 20.1 3.9 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Filament_head PF04732.14 KFP20185.1 - 0.07 14.0 0.7 0.26 12.2 0.2 2.2 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Macoilin PF09726.9 KFP20185.1 - 0.79 8.2 31.1 1.1 7.7 31.1 1.2 1 0 0 1 1 1 0 Macoilin family FUSC PF04632.12 KFP20185.1 - 1.7 7.1 2.7 2.9 6.3 2.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERM PF00769.19 KFP20185.1 - 1.9 8.2 44.7 0.56 10.0 34.5 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Fez1 PF06818.15 KFP20185.1 - 4 7.9 44.4 7.3 7.0 33.6 2.4 2 0 0 2 2 2 0 Fez1 RFX_DNA_binding PF02257.15 KFP20186.1 - 2.6e-28 98.4 0.0 7e-26 90.7 0.0 2.5 2 0 0 2 2 2 2 RFX DNA-binding domain Pox_D5 PF03288.16 KFP20186.1 - 0.00017 22.0 0.1 0.00045 20.6 0.1 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.11 KFP20186.1 - 0.015 15.3 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4111 PF13427.6 KFP20186.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) fn3 PF00041.21 KFP20188.1 - 5.6e-62 206.1 4.8 1.3e-11 44.7 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFP20188.1 - 1.6e-56 188.3 0.0 2.4e-15 56.3 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP20188.1 - 8.1e-56 186.6 1.5 1.5e-13 51.1 0.0 5.1 5 0 0 5 5 4 4 Immunoglobulin domain ig PF00047.25 KFP20188.1 - 1.5e-34 118.0 0.0 4.9e-07 29.8 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP20188.1 - 6.9e-33 112.8 0.4 4.1e-08 33.4 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFP20188.1 - 1.7e-16 60.3 6.8 0.11 12.6 0.0 8.6 5 4 3 8 8 8 4 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KFP20188.1 - 1.6e-13 51.0 7.5 0.0019 18.7 0.1 6.2 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 KFP20188.1 - 4.7e-11 42.6 0.3 0.032 14.3 0.0 4.6 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 KFP20188.1 - 6.4e-08 32.6 0.1 0.0053 16.9 0.0 4.4 5 0 0 5 5 5 2 Fibronectin type III domain Ig_6 PF18452.1 KFP20188.1 - 5.4e-06 25.9 0.0 0.033 13.7 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin domain SusE PF14292.6 KFP20188.1 - 1.6e-05 25.0 0.3 0.7 10.2 0.0 4.8 4 0 0 4 4 4 1 SusE outer membrane protein Ig_4 PF16680.5 KFP20188.1 - 2.7e-05 24.3 0.0 0.57 10.5 0.0 4.2 3 1 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain fn3_4 PF16794.5 KFP20188.1 - 0.00055 19.8 2.4 0.036 14.0 0.0 4.4 5 0 0 5 5 5 1 Fibronectin-III type domain C1-set PF07654.15 KFP20188.1 - 0.00057 20.2 0.4 0.13 12.6 0.0 4.5 6 0 0 6 6 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP20188.1 - 0.00074 19.5 0.4 2.8 8.0 0.0 4.6 4 1 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP20188.1 - 0.003 17.5 0.1 4.2 7.5 0.0 4.1 4 0 0 4 4 4 1 C17orf99 Ig domain DUF2369 PF10179.9 KFP20188.1 - 0.0048 17.3 0.0 26 5.3 0.0 5.1 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Syndecan PF01034.20 KFP20188.1 - 0.011 15.7 0.3 0.21 11.5 1.0 2.4 2 0 0 2 2 2 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KFP20188.1 - 0.017 14.9 5.2 0.038 13.8 5.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycoprotein_G PF00802.19 KFP20188.1 - 0.058 12.8 0.6 0.11 11.8 0.6 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G PRIMA1 PF16101.5 KFP20188.1 - 0.15 12.1 0.6 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PHD PF00628.29 KFP20189.1 - 7.6e-07 28.9 5.7 1.3e-06 28.2 5.7 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KFP20189.1 - 0.0025 17.7 1.1 0.0058 16.5 1.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KFP20189.1 - 0.056 13.8 4.5 0.11 12.8 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 KFP20189.1 - 0.36 11.0 5.0 1.2 9.3 5.0 2.0 1 1 0 1 1 1 0 PHD-finger TP53IP5 PF15331.6 KFP20189.1 - 0.47 10.6 3.1 0.79 9.8 3.1 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_11 PF17123.5 KFP20189.1 - 0.69 9.7 4.6 1.4 8.8 4.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KFP20189.1 - 1.7 8.9 5.1 1 9.6 2.7 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain Macoilin PF09726.9 KFP20189.1 - 9.1 4.7 11.2 11 4.4 11.2 1.0 1 0 0 1 1 1 0 Macoilin family TPR_1 PF00515.28 KFP20190.1 - 2e-13 49.6 5.1 5.2e-06 26.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP20190.1 - 3.5e-10 39.2 9.1 0.0012 18.7 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP20190.1 - 2.9e-09 36.5 4.7 6.5e-05 22.5 0.7 2.8 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 KFP20190.1 - 3.6e-07 30.2 0.2 0.026 14.7 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP20190.1 - 1.3e-06 28.1 7.7 0.058 13.6 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP20190.1 - 2.3e-05 24.6 3.0 0.17 12.2 0.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP20190.1 - 0.0076 16.9 6.5 0.43 11.3 0.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP20190.1 - 0.065 14.1 0.1 7.9 7.6 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MCPVI PF02993.14 KFP20190.1 - 0.27 11.0 3.0 0.49 10.2 3.0 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Glyco_transf_41 PF13844.6 KFP20190.1 - 0.61 8.5 3.9 0.9 7.9 3.9 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 fn3_2 PF16893.5 KFP20190.1 - 0.81 9.9 4.4 0.72 10.1 0.5 2.7 3 0 0 3 3 3 0 Fibronectin type III domain TPR_17 PF13431.6 KFP20190.1 - 1.4 9.5 5.0 28 5.4 1.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF763 PF05559.11 KFP20190.1 - 2.6 7.2 8.5 4.2 6.5 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Glyco_transf_22 PF03901.17 KFP20191.1 - 7.3e-97 325.2 25.7 8.6e-97 325.0 25.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2368 PF10166.9 KFP20191.1 - 4.9 6.8 4.8 5.3 6.7 0.7 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Ras PF00071.22 KFP20192.1 - 7.8e-58 194.6 0.0 9.3e-58 194.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20192.1 - 3.1e-31 108.1 0.0 5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20192.1 - 6.6e-12 45.2 0.0 9.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP20192.1 - 6.4e-05 22.9 0.2 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP20192.1 - 0.00018 21.1 0.0 0.00043 19.9 0.0 1.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP20192.1 - 0.00066 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP-grasp_5 PF13549.6 KFP20192.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain TPP_enzyme_M PF00205.22 KFP20192.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain SRPRB PF09439.10 KFP20192.1 - 0.13 11.6 0.0 0.4 10.1 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP20192.1 - 0.18 11.0 0.6 6.2 5.9 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Ribosomal_L24e PF01246.20 KFP20193.1 - 8.8e-14 51.5 6.2 8.8e-14 51.5 6.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF1091 PF06477.13 KFP20193.1 - 0.055 14.0 0.5 0.096 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) Membr_traf_MHD PF10540.9 KFP20196.1 - 5.7e-51 172.6 1.1 3.3e-50 170.1 1.1 2.5 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFP20196.1 - 1.7e-43 147.1 8.1 9.9e-27 93.2 0.3 3.7 4 0 0 4 4 4 2 C2 domain DUF1041 PF06292.17 KFP20196.1 - 5.6e-35 119.9 0.2 5.6e-35 119.9 0.2 3.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 KFP20196.1 - 1.1e-10 41.2 6.2 1.1e-10 41.2 6.2 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Transposase_22 PF02994.14 KFP20196.1 - 0.0048 17.0 0.0 0.029 14.5 0.0 2.5 1 0 0 1 1 1 1 L1 transposable element RBD-like domain Med9 PF07544.13 KFP20196.1 - 0.012 15.7 0.5 0.08 13.0 0.5 2.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 KFP20196.1 - 0.016 15.6 2.5 0.16 12.4 2.5 2.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2205 PF10224.9 KFP20196.1 - 0.083 12.9 0.5 0.44 10.6 0.5 2.3 1 0 0 1 1 1 0 Short coiled-coil protein Mrr_N PF14338.6 KFP20196.1 - 0.1 12.7 0.2 0.9 9.7 0.1 2.8 2 0 0 2 2 2 0 Mrr N-terminal domain zf-RING-like PF08746.11 KFP20196.1 - 0.61 10.4 4.5 2.3 8.6 4.5 2.1 1 0 0 1 1 1 0 RING-like domain DUF1664 PF07889.12 KFP20196.1 - 6.7 6.8 9.3 0.16 12.0 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) C2 PF00168.30 KFP20198.1 - 3.4e-07 30.5 0.0 4.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain CUT PF02376.15 KFP20199.1 - 8e-32 109.2 0.7 1.2e-31 108.7 0.7 1.3 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 KFP20199.1 - 2.5e-10 40.0 0.7 4.9e-10 39.1 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP20199.1 - 0.00067 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Chromosome_seg PF13889.6 KFP20200.1 - 2.4e-19 69.2 0.3 5.3e-19 68.1 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFP20200.1 - 1.6e-13 51.0 0.1 4.9e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Endosulfine PF04667.17 KFP20201.1 - 6.9e-11 42.1 1.0 9.2e-11 41.7 1.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox30 PF15532.6 KFP20201.1 - 0.058 13.8 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 30 Myosin_head PF00063.21 KFP20202.1 - 4.6e-288 957.1 5.0 4.6e-288 957.1 5.0 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KFP20202.1 - 2.2e-32 111.5 1.6 2.2e-32 111.5 1.6 3.4 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KFP20202.1 - 1.2e-23 80.6 46.6 0.00018 21.0 3.8 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif Csm1_N PF18504.1 KFP20202.1 - 0.0032 17.8 3.0 0.0032 17.8 3.0 9.0 8 1 1 9 9 9 1 Csm1 N-terminal domain HTH_17 PF12728.7 KFP20202.1 - 0.011 15.9 0.2 4.1 7.7 0.0 3.9 3 0 0 3 3 3 0 Helix-turn-helix domain AAA_22 PF13401.6 KFP20202.1 - 0.014 15.7 0.6 0.084 13.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.19 KFP20202.1 - 0.024 14.5 0.2 0.064 13.1 0.2 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KFP20202.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain Myosin_head PF00063.21 KFP20203.1 - 1.2e-269 896.2 16.0 1.4e-269 896.0 16.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFP20203.1 - 1.7e-17 61.5 28.6 6.8e-06 25.4 0.8 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KFP20203.1 - 7.7e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 KFP20203.1 - 0.0052 17.2 0.0 0.059 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP20203.1 - 0.0056 17.0 0.1 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain R-HINP1I PF11463.8 KFP20203.1 - 0.032 13.7 0.9 0.31 10.5 0.0 2.8 2 1 1 3 3 3 0 R.HinP1I restriction endonuclease Sigma54_activat PF00158.26 KFP20203.1 - 0.071 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KFP20203.1 - 0.076 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.18 KFP20203.1 - 0.083 12.6 0.3 0.32 10.7 0.4 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DIL PF01843.19 KFP20204.1 - 4.6e-28 97.5 1.2 4.6e-28 97.5 1.2 3.3 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KFP20204.1 - 0.0015 18.1 2.4 0.0015 18.1 2.4 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Csm1_N PF18504.1 KFP20204.1 - 0.0034 17.7 2.3 0.0034 17.7 2.3 9.3 5 2 3 8 8 8 2 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KFP20204.1 - 0.013 15.5 2.7 0.013 15.5 2.7 8.8 4 2 5 10 10 10 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KFP20204.1 - 3.7 6.8 57.5 8.6 5.6 18.9 4.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4407) WD40 PF00400.32 KFP20205.1 - 7.9e-36 121.5 22.0 3.4e-07 30.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP20205.1 - 1.8e-13 50.6 0.1 0.056 13.7 0.0 5.4 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFP20205.1 - 1.6e-05 24.4 0.1 0.6 9.4 0.0 4.0 2 1 2 4 4 4 3 WD40-like domain Pkinase PF00069.25 KFP20206.1 - 3.2e-70 236.5 0.0 4.8e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20206.1 - 1.2e-25 90.3 0.0 2.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP20206.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Leo1 PF04004.13 KFP20207.1 - 4.4e-54 182.7 0.0 4.4e-54 182.7 0.0 3.3 2 1 0 2 2 2 1 Leo1-like protein Tropomodulin PF03250.14 KFP20208.1 - 4.1e-39 133.9 5.5 6.4e-39 133.2 3.6 2.2 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFP20208.1 - 0.0063 16.5 1.4 0.019 15.0 0.1 2.6 2 0 0 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.7 KFP20208.1 - 1 9.9 5.6 3.7 8.1 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Tropomodulin PF03250.14 KFP20209.1 - 1.5e-42 145.0 4.8 3.4e-42 143.9 3.0 2.4 2 1 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFP20209.1 - 0.045 13.8 3.4 0.099 12.7 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 KFP20209.1 - 1.1 9.8 7.3 3.3 8.3 0.1 3.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Hormone_2 PF00123.20 KFP20210.1 - 1.8 8.5 0.0 1.8 8.5 0.0 2.5 3 0 0 3 3 3 0 Peptide hormone SGIII PF15467.6 KFP20211.1 - 2.1e-221 736.0 34.9 2.3e-221 735.8 34.9 1.0 1 0 0 1 1 1 1 Secretogranin-3 DUF2680 PF10925.8 KFP20211.1 - 0.00011 22.1 13.6 0.087 12.8 0.2 4.6 5 0 0 5 5 5 3 Protein of unknown function (DUF2680) ParE_toxin PF05016.15 KFP20211.1 - 0.43 11.2 2.1 3.1 8.5 0.1 3.1 2 2 2 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE DUF758 PF05527.11 KFP20212.1 - 1.9e-80 269.2 7.1 2.1e-80 269.0 7.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RPAP3_C PF13877.6 KFP20212.1 - 0.015 15.9 1.3 0.038 14.5 0.7 1.9 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Seadorna_VP6 PF07407.11 KFP20212.1 - 0.022 13.7 1.4 0.028 13.4 0.4 1.4 1 1 0 1 1 1 0 Seadornavirus VP6 protein Rsd_AlgQ PF04353.13 KFP20212.1 - 0.028 14.4 3.4 0.86 9.5 2.4 2.1 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CdvA PF18822.1 KFP20212.1 - 0.046 13.6 1.5 0.046 13.6 1.5 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF2408 PF10303.9 KFP20212.1 - 0.077 13.6 1.7 0.38 11.3 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DALR_1 PF05746.15 KFP20212.1 - 0.14 12.4 2.2 0.2 11.8 1.7 1.5 1 1 0 1 1 1 0 DALR anticodon binding domain p450 PF00067.22 KFP20215.1 - 2.1e-96 323.5 0.1 2.5e-96 323.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 OLF PF02191.16 KFP20217.1 - 3.2e-64 216.9 1.5 3.7e-64 216.6 1.5 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.18 KFP20217.1 - 1.1e-15 57.1 68.2 1.6e-09 37.4 27.2 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Rav1p_C PF12234.8 KFP20219.1 - 1.5e-83 281.3 0.1 2.2e-72 244.4 0.1 2.3 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 KFP20219.1 - 1.7e-12 47.6 25.8 0.0036 18.1 0.0 11.1 12 0 0 12 12 12 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP20219.1 - 6.5e-06 26.4 0.1 0.72 10.2 0.0 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP20219.1 - 0.00065 19.6 0.5 2.2 8.1 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Opiods_neuropep PF01160.18 KFP20219.1 - 1.3 9.2 3.6 3 8.0 0.1 3.0 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide Sema PF01403.19 KFP20225.1 - 2.7e-122 408.6 0.0 5.2e-122 407.7 0.0 1.3 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KFP20225.1 - 3.6e-05 24.2 3.5 9e-05 22.9 3.5 1.7 1 0 0 1 1 1 1 Plexin repeat PP1_bind PF15276.6 KFP20225.1 - 1.7 9.0 5.8 2.5 8.5 0.7 2.9 2 0 0 2 2 2 0 Protein phosphatase 1 binding Na_Ca_ex PF01699.24 KFP20226.1 - 1.3e-49 168.1 41.5 7.1e-28 97.5 18.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2456 PF10445.9 KFP20226.1 - 0.43 10.7 6.6 0.42 10.7 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) SPC25 PF06703.11 KFP20226.1 - 2.8 7.7 6.9 0.32 10.8 1.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_1 PF00076.22 KFP20227.1 - 2.2e-56 187.6 0.3 5.7e-19 67.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP20227.1 - 1.6e-08 34.5 0.6 0.0046 17.0 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFP20227.1 - 3.3e-06 27.1 0.0 0.012 15.6 0.0 2.9 2 1 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 KFP20227.1 - 4.3e-05 23.1 0.0 0.058 13.0 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP20227.1 - 0.0019 18.0 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFP20227.1 - 0.0043 16.9 0.0 18 5.1 0.0 3.7 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain DUF3932 PF13068.6 KFP20227.1 - 0.0072 16.6 0.0 1.5 9.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3932) DbpA PF03880.15 KFP20227.1 - 0.073 13.1 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain dUTPase PF00692.19 KFP20228.1 - 1.2e-24 86.5 0.0 1.3e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase PCI PF01399.27 KFP20229.1 - 6.8e-26 90.8 1.8 6.8e-26 90.8 1.8 2.6 3 0 0 3 3 3 1 PCI domain DUF2087 PF09860.9 KFP20229.1 - 0.079 13.1 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) TPR_1 PF00515.28 KFP20229.1 - 0.15 11.9 3.0 7.7 6.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP20229.1 - 0.17 12.1 2.5 20 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP20229.1 - 0.21 11.7 5.1 74 3.7 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat FliS PF02561.14 KFP20229.1 - 0.55 10.5 6.9 0.55 10.5 4.1 2.6 2 1 0 2 2 2 0 Flagellar protein FliS GalKase_gal_bdg PF10509.9 KFP20230.1 - 1.9e-24 85.0 0.0 3.7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KFP20230.1 - 1.2e-13 51.1 0.3 3e-13 49.8 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFP20230.1 - 6.5e-13 48.9 0.0 2.2e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal TPD52 PF04201.15 KFP20230.1 - 0.039 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Tumour protein D52 family FGF PF00167.18 KFP20232.1 - 6.2e-49 165.2 1.9 8e-49 164.9 1.9 1.1 1 0 0 1 1 1 1 Fibroblast growth factor DTW PF03942.15 KFP20233.1 - 5.8e-47 160.0 0.0 9.2e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 DTW domain AAA PF00004.29 KFP20236.1 - 1.3e-65 219.8 0.0 8.3e-37 126.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP20236.1 - 9e-30 102.2 4.7 1.6e-12 47.0 0.3 3.6 3 0 0 3 3 3 3 AAA+ lid domain AAA_2 PF07724.14 KFP20236.1 - 4e-08 33.6 0.0 0.0039 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFP20236.1 - 3.3e-07 30.4 0.0 0.0011 18.9 0.0 3.9 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 KFP20236.1 - 9.3e-07 28.8 0.2 5.9e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 KFP20236.1 - 2.6e-05 24.6 0.1 0.00064 20.2 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFP20236.1 - 0.0013 18.5 0.0 0.018 14.8 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFP20236.1 - 0.0018 18.3 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP20236.1 - 0.0043 17.3 0.0 4.4 7.6 0.2 3.5 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 KFP20236.1 - 0.0075 15.5 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 KFP20236.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KFP20236.1 - 0.015 15.3 0.3 0.054 13.4 0.2 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KFP20236.1 - 0.1 12.2 0.1 8.8 5.9 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP20236.1 - 0.12 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Cation_efflux PF01545.21 KFP20237.1 - 8.9e-48 162.7 13.9 1.1e-47 162.4 13.9 1.1 1 0 0 1 1 1 1 Cation efflux family PHO4 PF01384.20 KFP20237.1 - 0.0015 17.7 2.4 0.0017 17.5 2.4 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF1282 PF06930.12 KFP20237.1 - 0.015 15.1 9.5 0.17 11.6 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Polysacc_synt_C PF14667.6 KFP20237.1 - 0.21 11.7 9.1 0.032 14.3 4.3 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF3119 PF11317.8 KFP20237.1 - 1.4 9.2 3.8 2.2 8.6 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3119) Snapin_Pallidin PF14712.6 KFP20238.1 - 3e-22 78.9 4.7 3.7e-22 78.6 4.7 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF2353 PF09789.9 KFP20238.1 - 0.0044 16.4 1.2 0.0044 16.4 1.2 1.8 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Med2 PF11214.8 KFP20238.1 - 0.037 14.2 1.7 0.047 13.9 1.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 PIN_4 PF13638.6 KFP20238.1 - 0.058 13.7 0.5 0.07 13.4 0.5 1.1 1 0 0 1 1 1 0 PIN domain Tup_N PF08581.10 KFP20238.1 - 0.34 11.2 5.2 0.91 9.9 0.6 2.1 1 1 1 2 2 2 0 Tup N-terminal Pyr_redox_2 PF07992.14 KFP20239.1 - 1.6e-15 57.1 0.1 6.4e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Tox-PL-2 PF15643.6 KFP20239.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 AAA_18 PF13238.6 KFP20240.1 - 0.017 15.7 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PBD PF00786.28 KFP20241.1 - 3.9e-05 23.9 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Peptidase_A22B PF04258.13 KFP20242.1 - 5.5e-82 275.5 20.7 7.9e-82 275.0 20.7 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 KFP20242.1 - 3.1e-07 30.3 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Presenilin PF01080.17 KFP20242.1 - 0.00097 18.0 29.4 0.009 14.8 4.9 2.1 2 0 0 2 2 2 2 Presenilin UCH PF00443.29 KFP20243.1 - 9.6e-81 271.0 4.8 9.6e-81 271.0 4.8 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 KFP20243.1 - 1.7e-30 105.5 6.2 1.7e-30 105.5 6.2 2.6 2 1 0 2 2 2 1 USP8 dimerisation domain UCH_1 PF13423.6 KFP20243.1 - 1.7e-20 73.9 3.8 1.7e-20 73.9 3.8 2.5 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KFP20243.1 - 4e-08 33.7 0.0 2.5e-07 31.2 0.0 2.5 1 0 0 1 1 1 1 Rhodanese-like domain Metallothio_Pro PF02069.16 KFP20243.1 - 0.15 12.3 0.5 0.37 11.0 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic metallothionein DUF2052 PF09747.9 KFP20243.1 - 5.4 7.1 48.2 0.87 9.7 5.8 3.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ank_2 PF12796.7 KFP20244.1 - 2.9e-37 127.1 5.3 1.8e-15 57.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP20244.1 - 3.3e-25 87.8 0.4 1.4e-09 38.0 0.1 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP20244.1 - 2.6e-24 84.5 0.5 9.1e-09 35.4 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFP20244.1 - 1.3e-22 79.8 0.3 6.6e-10 39.3 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP20244.1 - 1.7e-21 74.0 0.1 2.9e-06 27.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat AAA_23 PF13476.6 KFP20244.1 - 0.042 14.4 1.5 0.059 13.9 1.5 1.3 1 0 0 1 1 1 0 AAA domain LAMTOR5 PF16672.5 KFP20244.1 - 0.056 13.4 0.4 0.16 11.9 0.2 1.9 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 DUF4265 PF14085.6 KFP20244.1 - 0.35 10.8 6.4 5.3 7.1 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4265) GrpE PF01025.19 KFP20244.1 - 1.1 8.9 10.1 3.2 7.4 10.1 1.8 1 0 0 1 1 1 0 GrpE TPD52 PF04201.15 KFP20244.1 - 1.4 8.6 6.4 2.7 7.6 6.4 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Pyridoxal_deC PF00282.19 KFP20245.1 - 1.4e-165 550.5 0.0 1.7e-165 550.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KFP20245.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFP20245.1 - 0.024 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Amidinotransf PF02274.17 KFP20246.1 - 4.3e-09 35.9 0.0 1.5e-05 24.3 0.0 3.3 3 1 0 3 3 3 3 Amidinotransferase PDEase_I PF00233.19 KFP20247.1 - 1.7e-96 322.5 1.0 3.2e-96 321.7 1.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS PF00989.25 KFP20247.1 - 3e-12 46.5 0.0 9.9e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFP20247.1 - 4.1e-12 46.3 0.1 1.1e-11 44.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KFP20247.1 - 3.9e-06 27.1 0.0 8.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KFP20247.1 - 1.7e-05 25.0 0.0 5.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KFP20247.1 - 0.014 15.5 0.0 0.044 13.8 0.0 1.9 1 0 0 1 1 1 0 PAS domain Nrap_D2 PF17403.2 KFP20247.1 - 0.13 12.0 0.3 0.4 10.4 0.3 1.7 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain fn3 PF00041.21 KFP20248.1 - 1.5e-17 63.7 0.0 1.2e-10 41.6 0.1 2.8 2 0 0 2 2 2 2 Fibronectin type III domain SPRY PF00622.28 KFP20248.1 - 9.2e-13 48.4 0.0 2.2e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP20248.1 - 0.0015 18.2 0.1 0.0091 15.6 0.0 2.4 2 0 0 2 2 2 1 SPRY-associated domain Pur_ac_phosph_N PF16656.5 KFP20248.1 - 0.0016 18.9 0.0 0.016 15.8 0.0 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain SPX PF03105.19 KFP20248.1 - 0.016 15.1 12.4 0.023 14.6 12.4 1.2 1 0 0 1 1 1 0 SPX domain Eapp_C PF10238.9 KFP20248.1 - 0.044 13.9 1.6 0.11 12.5 1.6 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein LpxB PF02684.15 KFP20248.1 - 0.097 11.5 0.5 0.16 10.8 0.5 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF5082 PF16888.5 KFP20248.1 - 6.5 7.1 7.2 2.2 8.6 2.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) JMY PF15871.5 KFP20249.1 - 4.4e-115 384.8 25.4 4.4e-115 384.8 25.4 2.1 2 0 0 2 2 2 1 Junction-mediating and -regulatory protein WH2 PF02205.20 KFP20249.1 - 0.00054 19.7 0.2 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 WH2 motif ZnuA PF01297.17 KFP20249.1 - 8.2 5.8 15.1 0.041 13.3 3.5 2.8 3 1 1 4 4 4 0 Zinc-uptake complex component A periplasmic WH1 PF00568.23 KFP20250.1 - 3.4e-36 123.5 0.4 7.9e-36 122.4 0.4 1.6 1 0 0 1 1 1 1 WH1 domain Macoilin PF09726.9 KFP20250.1 - 5e-06 25.4 24.3 5.7e-06 25.2 24.3 1.1 1 0 0 1 1 1 1 Macoilin family GAS PF13851.6 KFP20250.1 - 2.9e-05 23.5 47.8 0.00011 21.7 15.9 3.8 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding MAD PF05557.13 KFP20250.1 - 0.00036 19.1 40.2 0.0031 15.9 19.4 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein IFT57 PF10498.9 KFP20250.1 - 0.00045 19.3 25.1 0.00067 18.7 25.1 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DMPK_coil PF08826.10 KFP20250.1 - 0.00057 19.9 4.3 0.00057 19.9 4.3 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like Uso1_p115_C PF04871.13 KFP20250.1 - 0.00077 19.8 16.5 0.00077 19.8 16.5 3.3 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_DNA_bd PF12329.8 KFP20250.1 - 0.002 18.1 9.2 0.002 18.1 9.2 3.8 2 1 2 4 4 3 1 TATA element modulatory factor 1 DNA binding HemX PF04375.14 KFP20250.1 - 0.0024 17.3 7.8 0.0024 17.3 7.8 3.4 1 1 2 3 3 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase BST2 PF16716.5 KFP20250.1 - 0.006 17.1 9.6 0.006 17.1 9.6 4.0 2 1 1 4 4 3 1 Bone marrow stromal antigen 2 DUF4201 PF13870.6 KFP20250.1 - 0.006 16.3 6.8 0.006 16.3 6.8 3.2 2 1 1 3 3 2 2 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 KFP20250.1 - 0.0062 16.6 21.5 0.14 12.2 7.5 3.7 1 1 2 3 3 3 1 TolA binding protein trimerisation ATG16 PF08614.11 KFP20250.1 - 0.0074 16.5 21.2 0.0074 16.5 21.2 3.1 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 KFP20250.1 - 0.013 15.3 9.6 0.013 15.3 9.6 3.7 2 1 2 4 4 3 0 Phage minor structural protein GP20 FPP PF05911.11 KFP20250.1 - 0.022 12.9 43.6 0.033 12.4 28.1 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 KFP20250.1 - 0.024 15.0 22.2 1.9 8.9 0.7 4.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KFP20250.1 - 0.064 13.5 38.4 0.029 14.6 14.0 3.0 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 KFP20250.1 - 0.1 12.6 22.7 0.1 12.6 7.4 3.0 2 1 1 3 3 3 0 Laminin Domain II DUF3584 PF12128.8 KFP20250.1 - 0.11 10.0 35.7 0.0025 15.4 28.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) T3SSipB PF16535.5 KFP20250.1 - 0.12 12.8 23.4 0.097 13.2 16.5 2.8 2 1 1 3 3 3 0 Type III cell invasion protein SipB CALCOCO1 PF07888.11 KFP20250.1 - 0.12 11.2 35.6 0.27 10.0 33.3 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 KFP20250.1 - 0.18 12.3 39.0 0.046 14.2 7.7 3.1 1 1 2 3 3 3 0 Fez1 TACC_C PF05010.14 KFP20250.1 - 0.23 11.2 33.8 0.0094 15.8 25.5 2.5 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal VGPC1_C PF16799.5 KFP20250.1 - 0.24 11.4 19.9 0.2 11.7 5.6 3.6 2 1 1 3 3 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 CENP-H PF05837.12 KFP20250.1 - 0.43 11.0 42.9 0.12 12.8 11.5 4.0 2 1 0 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 KFP20250.1 - 0.43 11.2 32.4 0.4 11.3 7.7 4.2 1 1 2 4 4 4 0 Initiation control protein YabA DHR10 PF18595.1 KFP20250.1 - 0.57 10.3 50.7 0.56 10.3 8.9 4.0 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KFP20250.1 - 0.57 10.7 11.7 4.5e+02 1.4 8.7 3.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KFP20250.1 - 0.61 10.2 39.7 47 4.0 38.4 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFP20250.1 - 0.63 8.5 12.0 12 4.3 7.4 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF3450 PF11932.8 KFP20250.1 - 0.79 9.0 33.5 0.29 10.4 3.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 KFP20250.1 - 0.8 8.5 40.2 2.1 7.1 24.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Sec34 PF04136.15 KFP20250.1 - 0.84 9.5 26.1 0.42 10.5 4.4 3.4 2 1 2 4 4 4 0 Sec34-like family HAP1_N PF04849.13 KFP20250.1 - 0.91 8.7 41.9 0.5 9.5 29.6 2.5 2 1 1 3 3 2 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 KFP20250.1 - 0.92 9.6 21.7 2 8.5 5.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KFP20250.1 - 0.99 7.3 17.4 3.2 5.6 17.1 1.8 1 1 0 1 1 1 0 Prominin DUF948 PF06103.11 KFP20250.1 - 1.1 9.6 8.9 3.1 8.1 0.4 2.8 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 KFP20250.1 - 1.1 9.0 50.3 0.35 10.6 38.4 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Leu_zip PF15294.6 KFP20250.1 - 1.3 8.5 34.3 0.13 11.7 27.5 2.3 1 1 1 2 2 2 0 Leucine zipper CENP-F_leu_zip PF10473.9 KFP20250.1 - 1.4 9.0 48.0 0.55 10.2 2.1 4.3 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 KFP20250.1 - 1.4 9.3 25.1 0.38 11.1 2.5 3.8 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4600 PF15372.6 KFP20250.1 - 1.8 9.0 26.9 0.19 12.2 8.9 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4600) MscS_porin PF12795.7 KFP20250.1 - 2.2 7.8 36.8 0.85 9.1 15.3 3.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 KFP20250.1 - 2.2 8.1 47.7 0.14 12.0 23.8 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CLZ PF16526.5 KFP20250.1 - 2.3 8.6 25.1 1.2 9.5 3.8 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mod_r PF07200.13 KFP20250.1 - 2.4 8.3 38.5 0.71 10.0 19.9 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lebercilin PF15619.6 KFP20250.1 - 2.6 7.7 44.1 1.7 8.3 19.9 3.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BRI3BP PF14965.6 KFP20250.1 - 2.6 7.5 12.2 2.5 7.6 1.0 2.9 2 2 2 4 4 4 0 Negative regulator of p53/TP53 Dor1 PF04124.12 KFP20250.1 - 2.9 6.5 23.6 0.11 11.2 17.5 1.7 2 1 0 2 2 1 0 Dor1-like family Filament PF00038.21 KFP20250.1 - 3 7.3 35.1 1.5 8.3 11.4 2.8 1 1 1 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 KFP20250.1 - 3.2 6.5 42.0 0.3 9.9 19.8 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 KFP20250.1 - 3.4 7.8 40.9 11 6.1 16.0 4.5 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 KFP20250.1 - 3.6 7.7 53.0 0.15 12.1 6.3 4.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FOXP-CC PF16159.5 KFP20250.1 - 4 8.1 10.9 0.42 11.3 2.1 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain AIP3 PF03915.13 KFP20250.1 - 4.3 6.3 30.5 0.6 9.1 13.5 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 ADIP PF11559.8 KFP20250.1 - 4.6 7.3 44.7 1.8 8.6 5.0 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding ApoO PF09769.9 KFP20250.1 - 5.2 7.0 8.8 6 6.8 0.1 3.1 3 1 0 3 3 2 0 Apolipoprotein O Jnk-SapK_ap_N PF09744.9 KFP20250.1 - 5.5 7.2 49.2 0.076 13.2 25.2 3.1 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 EzrA PF06160.12 KFP20250.1 - 7.9 4.5 34.5 0.22 9.7 27.3 1.9 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA FH2 PF02181.23 KFP20250.1 - 8.1 5.4 23.7 12 4.9 5.7 3.5 2 1 1 3 3 3 0 Formin Homology 2 Domain MerR-DNA-bind PF09278.11 KFP20250.1 - 8.5 7.0 17.1 2.8e+02 2.1 0.0 4.7 2 2 1 3 3 3 0 MerR, DNA binding KLRAQ PF10205.9 KFP20250.1 - 9.1 6.6 32.6 7.9 6.8 10.2 4.3 2 1 2 4 4 4 0 Predicted coiled-coil domain-containing protein HMMR_N PF15905.5 KFP20250.1 - 9.4 5.6 44.1 0.37 10.2 35.3 2.3 1 1 1 2 2 1 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 KFP20250.1 - 9.5 5.2 38.0 6.8 5.7 26.2 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RAM PF15320.6 KFP20251.1 - 4e-20 72.2 1.7 4.4e-20 72.1 1.7 1.0 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein DUF167 PF02594.16 KFP20252.1 - 1.1e-19 70.3 0.5 1.3e-19 70.0 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 PHR PF08005.12 KFP20253.1 - 2.4e-50 171.1 0.8 3.5e-50 170.6 0.8 1.2 1 0 0 1 1 1 1 PHR domain BACK PF07707.15 KFP20253.1 - 8.9e-10 38.6 0.2 1.4e-08 34.7 0.1 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP20253.1 - 7.5e-07 29.4 0.3 2.4e-05 24.5 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain PWWP PF00855.17 KFP20254.1 - 0.00024 21.4 0.0 0.00024 21.4 0.0 2.4 2 1 0 2 2 2 1 PWWP domain Raftlin PF15250.6 KFP20254.1 - 4.2 6.0 12.2 5.5 5.6 12.2 1.0 1 0 0 1 1 1 0 Raftlin BAR PF03114.18 KFP20255.1 - 3e-73 246.4 6.9 3.6e-73 246.1 6.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFP20255.1 - 9.1e-15 54.0 0.1 2.9e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP20255.1 - 1.2e-13 50.5 0.0 3.7e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFP20255.1 - 1.9e-13 50.0 0.1 3.1e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KFP20255.1 - 9.9e-08 31.5 3.4 3.2e-06 26.5 1.2 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFP20255.1 - 0.0002 21.1 5.1 0.0031 17.2 5.0 2.4 1 1 0 1 1 1 1 BAR domain of APPL family DUF4423 PF14394.6 KFP20255.1 - 0.11 12.2 1.4 0.38 10.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) PARP_reg PF02877.14 KFP20255.1 - 0.26 11.4 2.5 0.41 10.7 0.7 2.3 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Csm2_III-A PF03750.13 KFP20255.1 - 0.41 11.5 3.2 0.38 11.6 0.7 2.2 2 0 0 2 2 2 0 Csm2 Type III-A Filament PF00038.21 KFP20256.1 - 4e-56 190.9 48.7 1.6e-55 188.9 48.7 1.8 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KFP20256.1 - 2.6e-17 63.2 0.1 5.2e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Lamin Tail Domain GIT_CC PF16559.5 KFP20256.1 - 0.058 13.3 6.7 0.82 9.6 0.5 3.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor NUP50 PF08911.11 KFP20256.1 - 0.26 12.0 5.4 6.7 7.5 0.3 3.7 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) DUF1664 PF07889.12 KFP20256.1 - 5.6 7.0 22.1 2.6 8.1 2.5 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4713 PF15831.5 KFP20257.1 - 1 9.9 3.6 1.9 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) GTP_EFTU PF00009.27 KFP20259.1 - 2.1e-60 203.6 0.0 1.1e-59 201.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFP20259.1 - 6.3e-18 64.6 0.0 2e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KFP20259.1 - 6.9e-09 35.7 0.2 2.3e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFP20259.1 - 7.9e-09 35.8 0.0 4.3e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KFP20259.1 - 0.00082 19.1 0.1 0.0098 15.7 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KFP20259.1 - 0.0099 16.0 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase SSXT PF05030.12 KFP20259.1 - 0.054 13.1 0.8 0.14 11.8 0.8 1.8 1 0 0 1 1 1 0 SSXT protein (N-terminal region) G-alpha PF00503.20 KFP20259.1 - 0.058 12.6 1.4 3.7 6.6 0.0 3.2 3 0 0 3 3 3 0 G-protein alpha subunit RVT_1 PF00078.27 KFP20260.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMC PF07810.13 KFP20263.1 - 1.6e-40 138.1 2.2 1.6e-40 138.1 2.2 2.7 3 0 0 3 3 3 1 TMC domain TMEM43 PF07787.12 KFP20263.1 - 0.26 10.6 1.7 0.54 9.6 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 Orf78 PF06024.12 KFP20263.1 - 0.43 10.9 8.4 0.25 11.6 0.2 4.1 3 0 0 3 3 3 0 Orf78 (ac78) START PF01852.19 KFP20264.1 - 4.5e-19 68.7 0.0 5.1e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 START domain PDZ PF00595.24 KFP20265.1 - 3.1e-23 81.9 0.8 4.9e-13 49.2 0.3 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP20265.1 - 1.3e-09 37.8 0.1 1.5e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP20265.1 - 3e-07 30.7 0.6 0.00016 21.9 0.3 2.9 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 KFP20266.1 - 8.6e-22 77.3 1.6 6.8e-18 64.8 0.0 3.2 3 1 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KFP20266.1 - 7.9e-13 48.0 0.0 2.2e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP20266.1 - 1.4e-06 28.5 0.0 0.00094 19.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Mesd PF10185.9 KFP20269.1 - 1.1e-66 223.5 0.1 1.3e-66 223.3 0.1 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor PSII_BNR PF14870.6 KFP20269.1 - 0.023 13.9 0.0 0.065 12.5 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 ILEI PF15711.5 KFP20270.1 - 3.5e-41 139.6 0.6 1.9e-24 85.9 0.0 3.3 3 0 0 3 3 3 2 Interleukin-like EMT inducer G8 PF10162.9 KFP20270.1 - 1.5e-28 99.4 0.0 3e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 G8 domain Mucin2_WxxW PF13330.6 KFP20270.1 - 1.3e-14 54.8 0.4 3.5e-13 50.2 0.2 2.5 2 0 0 2 2 2 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.6 KFP20270.1 - 0.016 15.1 1.7 1.9 8.3 1.2 3.8 2 1 1 3 3 3 0 Right handed beta helix region Hydrolase_4 PF12146.8 KFP20271.1 - 1.6e-13 50.5 0.0 2.6e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFP20271.1 - 1.3e-07 31.6 0.1 0.0071 16.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFP20271.1 - 1.6e-07 32.1 0.0 0.00014 22.6 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFP20271.1 - 7.6e-07 28.8 0.0 2.6e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.12 KFP20271.1 - 0.00076 19.5 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 KFP20271.1 - 0.00086 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.12 KFP20271.1 - 0.0012 17.9 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.7 KFP20271.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KFP20271.1 - 0.0057 16.3 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Asp2 PF16929.5 KFP20271.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 KFP20271.1 - 0.0092 15.8 0.0 0.054 13.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase PAS_3 PF08447.12 KFP20272.1 - 1.7e-24 85.9 0.0 1.5e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KFP20272.1 - 2e-23 82.6 0.0 9.7e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP20272.1 - 1.2e-21 77.0 0.6 1.3e-18 67.2 0.2 3.1 2 1 1 3 3 3 2 PAS domain HLH PF00010.26 KFP20272.1 - 3e-14 52.7 1.2 5.8e-14 51.8 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KFP20272.1 - 8.8e-12 45.2 0.0 6.6e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFP20272.1 - 4.2e-05 23.8 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 KFP20272.1 - 0.014 16.0 0.0 0.19 12.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold CTNNBL PF08216.11 KFP20273.1 - 7.9e-39 132.0 1.5 2.5e-38 130.4 1.5 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KFP20273.1 - 0.0053 16.8 4.1 8.9 6.5 0.0 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RecO_C PF02565.15 KFP20273.1 - 0.043 13.6 1.1 39 4.0 0.1 3.6 2 1 0 3 3 3 0 Recombination protein O C terminal Atx10homo_assoc PF09759.9 KFP20273.1 - 0.044 13.8 0.1 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DASH_Dad4 PF08650.10 KFP20273.1 - 0.071 13.1 0.8 11 6.1 0.1 3.8 3 0 0 3 3 3 0 DASH complex subunit Dad4 Nup160 PF11715.8 KFP20274.1 - 9.3e-105 351.3 0.1 1.2e-104 350.9 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 LRR_8 PF13855.6 KFP20275.1 - 2.7e-46 155.1 40.0 7.6e-15 54.4 5.8 6.6 2 2 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFP20275.1 - 2.2e-21 75.6 37.3 2e-06 28.1 0.4 7.3 6 1 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP20275.1 - 1.4e-17 63.8 0.0 1.2e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP20275.1 - 5.8e-08 32.4 20.0 0.028 13.9 0.5 5.1 2 2 4 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 KFP20275.1 - 6.9e-06 25.9 37.0 1.1 10.1 0.2 11.9 12 1 0 12 12 12 3 Leucine Rich Repeat LRRNT PF01462.18 KFP20275.1 - 0.71 9.6 9.6 0.19 11.4 2.5 3.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain 7tm_2 PF00002.24 KFP20276.1 - 2.8e-84 282.3 20.7 3.7e-84 281.8 20.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP20276.1 - 5.7e-22 77.8 3.4 1.2e-21 76.8 3.4 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF1980 PF09323.10 KFP20276.1 - 7.3 6.5 8.3 0.59 10.0 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) 7tm_2 PF00002.24 KFP20278.1 - 5e-84 281.4 16.4 6.1e-84 281.2 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP20278.1 - 5.3e-19 68.3 2.7 5.3e-19 68.3 2.7 1.9 2 0 0 2 2 2 1 Hormone receptor domain S1FA PF04689.13 KFP20278.1 - 0.28 11.4 0.5 0.97 9.6 0.5 1.9 1 0 0 1 1 1 0 DNA binding protein S1FA Intron_maturas2 PF01348.21 KFP20278.1 - 0.54 10.2 3.1 0.8 9.7 0.0 2.5 3 0 0 3 3 3 0 Type II intron maturase 7tm_2 PF00002.24 KFP20279.1 - 2.2e-86 289.2 11.9 3e-86 288.7 11.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP20279.1 - 2.9e-21 75.5 0.3 2.9e-21 75.5 0.3 2.3 2 0 0 2 2 2 1 Hormone receptor domain Na_Ca_ex PF01699.24 KFP20279.1 - 0.0058 16.6 2.2 0.0058 16.6 2.2 2.2 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Insulin_TMD PF17870.1 KFP20279.1 - 0.043 13.9 0.6 0.17 12.0 0.6 2.0 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 7tm_2 PF00002.24 KFP20283.1 - 1e-84 283.7 19.3 1.3e-84 283.3 19.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP20283.1 - 2.8e-20 72.4 1.4 6.8e-20 71.1 1.4 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFP20283.1 - 0.00013 21.2 16.4 0.0002 20.6 16.4 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF2871 PF11070.8 KFP20283.1 - 0.015 15.5 1.9 0.4 11.0 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) MIP PF00230.20 KFP20284.1 - 5.7e-80 268.3 10.2 6.7e-80 268.0 10.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4205 PF13898.6 KFP20285.1 - 3.6e-134 447.1 0.0 4.1e-134 446.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) DUF4462 PF14692.6 KFP20287.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) 7tm_2 PF00002.24 KFP20288.1 - 1.8e-76 256.7 23.5 2.2e-76 256.4 23.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 KFP20288.1 - 5.3e-19 68.3 3.0 1.2e-18 67.1 3.0 1.6 1 0 0 1 1 1 1 Hormone receptor domain zf-H2C2_2 PF13465.6 KFP20291.1 - 2.1e-10 40.5 6.3 0.00012 22.3 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFP20291.1 - 1.3e-09 38.0 13.6 2.6e-05 24.4 1.6 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP20291.1 - 4.3e-07 30.2 10.8 0.00074 20.1 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf_UBZ PF18439.1 KFP20291.1 - 4.6e-05 22.9 3.6 0.1 12.2 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP20291.1 - 0.00069 19.7 2.3 0.004 17.2 0.8 2.2 1 1 0 2 2 2 1 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFP20291.1 - 0.0027 18.0 3.3 0.68 10.3 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP20291.1 - 0.0044 17.0 6.0 2.9 8.0 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-AN1 PF01428.16 KFP20291.1 - 0.017 15.3 4.4 2 8.7 0.1 2.7 3 0 0 3 3 3 0 AN1-like Zinc finger Evr1_Alr PF04777.13 KFP20291.1 - 0.017 15.6 0.7 0.24 11.9 0.1 2.0 1 1 1 2 2 2 0 Erv1 / Alr family HypA PF01155.19 KFP20291.1 - 0.021 14.9 0.3 0.023 14.7 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KFP20291.1 - 0.049 13.9 5.1 0.59 10.4 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon zf-met PF12874.7 KFP20291.1 - 0.06 13.8 4.2 1 9.8 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.13 KFP20291.1 - 0.065 12.9 1.2 1.5 8.6 0.1 2.8 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.12 KFP20291.1 - 0.076 13.3 1.9 0.66 10.3 1.5 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-LYAR PF08790.11 KFP20291.1 - 0.1 12.5 7.4 0.77 9.7 0.3 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger TFIIS_C PF01096.18 KFP20291.1 - 0.29 11.0 3.8 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DUF2256 PF10013.9 KFP20291.1 - 0.35 11.0 6.6 6.3 7.0 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 KFP20291.1 - 0.4 10.7 2.3 8.8 6.4 0.1 2.7 2 1 1 3 3 3 0 CpXC protein zf-Di19 PF05605.12 KFP20291.1 - 2.1 8.7 6.2 16 5.9 0.2 2.4 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HNH PF01844.23 KFP20291.1 - 2.8 8.2 7.2 1.6 8.9 1.0 2.8 3 0 0 3 3 3 0 HNH endonuclease HGTP_anticodon PF03129.20 KFP20292.1 - 6.6e-24 83.9 0.1 4.6e-23 81.2 0.0 2.4 2 1 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFP20292.1 - 2.8e-10 40.5 0.1 1.1e-09 38.5 0.0 2.2 3 1 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 KFP20292.1 - 5.8e-08 32.8 6.1 5.8e-08 32.8 6.1 2.2 2 0 0 2 2 2 1 WHEP-TRS domain OS-D PF03392.13 KFP20292.1 - 0.029 14.5 0.1 0.091 12.9 0.1 1.8 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D EcoRII-C PF09019.11 KFP20292.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 EcoRII C terminal NIF PF03031.18 KFP20297.1 - 5.3e-53 179.0 0.0 6.5e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Gelsolin PF00626.22 KFP20298.1 - 9.6e-96 313.8 0.0 8.4e-19 67.3 0.0 6.4 6 0 0 6 6 6 6 Gelsolin repeat PI-PLC-X PF00388.19 KFP20299.1 - 3.2e-68 227.9 0.8 2e-67 225.3 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 KFP20299.1 - 4.8e-37 126.3 4.4 8.9e-35 119.1 0.3 3.5 3 0 0 3 3 2 2 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.19 KFP20299.1 - 6.3e-30 103.9 0.0 1.9e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_10 PF14788.6 KFP20299.1 - 2.6e-22 78.4 4.3 5.9e-22 77.3 4.3 1.7 1 0 0 1 1 1 1 EF hand C2 PF00168.30 KFP20299.1 - 2.9e-20 72.5 0.8 6.8e-20 71.3 0.3 2.0 2 0 0 2 2 2 1 C2 domain PH_12 PF16457.5 KFP20299.1 - 6.7e-08 33.2 0.3 3.2e-07 31.0 0.3 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP20299.1 - 9.3e-07 29.3 0.7 4e-06 27.3 0.7 2.1 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 KFP20299.1 - 8.1e-05 21.9 2.7 0.0051 16.3 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KFP20299.1 - 0.00045 20.6 3.9 0.0013 19.2 2.4 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP20299.1 - 0.00067 19.4 1.6 0.1 12.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFP20299.1 - 0.021 14.3 0.1 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 KFP20299.1 - 0.18 12.1 4.9 0.47 10.8 4.9 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ASH PF15780.5 KFP20300.1 - 4.8e-17 62.0 3.2 0.035 14.3 0.0 8.6 9 0 0 9 9 9 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP20300.1 - 4.9e-06 26.7 1.0 0.016 15.4 0.0 4.3 4 0 0 4 4 4 2 Transmembrane protein 131-like PapD-like PF14874.6 KFP20300.1 - 0.00024 21.2 1.8 0.32 11.2 0.1 3.5 4 0 0 4 4 4 2 Flagellar-associated PapD-like MYCBPAP PF14646.6 KFP20300.1 - 7.2 5.4 9.9 2.3 7.1 0.0 3.5 3 1 0 4 4 4 0 MYCBP-associated protein family Thiolase_N PF00108.23 KFP20301.1 - 1.5e-79 267.0 0.8 2.3e-79 266.4 0.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP20301.1 - 2e-49 166.3 1.1 2.8e-49 165.9 0.3 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KFP20301.1 - 0.00024 21.2 0.0 0.00076 19.6 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KFP20301.1 - 0.00035 20.4 1.5 0.083 12.7 0.1 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KFP20301.1 - 0.0047 16.5 0.9 0.03 13.9 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain TIR_2 PF13676.6 KFP20302.1 - 1.2e-12 48.4 0.0 1.7e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KFP20302.1 - 9.1e-11 41.9 0.2 1.8e-10 40.9 0.1 1.5 1 1 1 2 2 2 1 TIR domain Pkinase PF00069.25 KFP20303.1 - 1e-60 205.3 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20303.1 - 4.6e-44 150.6 0.0 6.5e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KFP20303.1 - 2.3e-21 75.7 0.0 4.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 KFP20303.1 - 0.00011 21.1 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP20303.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP20303.1 - 0.16 11.3 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 KFP20304.1 - 9.6e-31 107.0 38.0 5.4e-28 97.9 24.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP20304.1 - 1.1e-30 107.0 17.3 3e-30 105.5 17.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFP20304.1 - 1.3e-06 27.3 7.8 0.0003 19.5 1.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TPR_8 PF13181.6 KFP20304.1 - 0.015 15.4 0.0 0.27 11.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KFP20305.1 - 9.8e-38 130.2 9.9 1.3e-37 129.8 9.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP20305.1 - 8.1e-32 110.5 18.1 8.1e-32 110.5 18.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFP20305.1 - 7.6e-06 24.7 9.2 0.00084 18.0 1.7 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TPR_8 PF13181.6 KFP20305.1 - 0.054 13.7 0.0 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LIM PF00412.22 KFP20306.1 - 3.3e-08 33.6 11.7 3.7e-08 33.5 11.7 1.0 1 0 0 1 1 1 1 LIM domain Xin PF08043.12 KFP20307.1 - 3e-161 517.8 75.1 2.6e-09 36.3 0.3 28.3 29 0 0 29 29 29 26 Xin repeat DinB PF05163.12 KFP20307.1 - 0.011 15.7 4.9 0.045 13.7 0.0 2.9 2 0 0 2 2 2 0 DinB family PNPase PF03726.14 KFP20307.1 - 0.32 11.5 12.3 0.012 16.1 2.7 3.8 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RhoGAP PF00620.27 KFP20307.1 - 0.37 10.6 3.0 0.4 10.5 0.7 2.3 2 0 0 2 2 2 0 RhoGAP domain CSRNP_N PF16019.5 KFP20310.1 - 1.9e-104 348.4 9.6 3e-104 347.7 9.6 1.3 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus GRASP55_65 PF04495.14 KFP20311.1 - 8.3e-73 243.2 0.0 4.6e-56 188.9 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KFP20311.1 - 1.2e-07 31.9 0.0 0.00055 20.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP20311.1 - 2.4e-06 27.3 0.2 0.14 12.0 0.0 3.2 2 2 0 2 2 2 2 PDZ domain DUF3337 PF11816.8 KFP20312.1 - 8.3e-50 169.0 0.1 2.9e-49 167.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KFP20312.1 - 1.9e-29 101.3 7.0 4.8e-05 24.1 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP20312.1 - 3.2e-07 30.6 2.9 0.036 14.4 0.2 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KFP20312.1 - 0.0084 14.9 0.5 0.92 8.2 0.0 3.2 1 1 2 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 KFP20312.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 WD40-like domain RAWUL PF16207.5 KFP20312.1 - 0.018 15.7 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Nup160 PF11715.8 KFP20312.1 - 0.18 10.4 8.5 1.5 7.4 0.2 4.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ion_trans PF00520.31 KFP20313.1 - 1e-252 833.8 102.1 4.4e-79 265.2 15.3 4.2 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.13 KFP20313.1 - 2.5e-67 227.1 5.5 2.5e-67 227.1 5.5 2.0 2 0 0 2 2 2 1 Sodium ion transport-associated Na_trans_cytopl PF11933.8 KFP20313.1 - 1.1e-52 178.9 2.4 1.4e-52 178.7 1.0 1.9 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel PKD_channel PF08016.12 KFP20313.1 - 3.2e-11 42.6 88.5 1.8e-06 26.9 2.7 9.8 6 4 2 9 9 9 8 Polycystin cation channel GPHH PF16905.5 KFP20313.1 - 0.00025 20.8 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 KFP20313.1 - 0.0015 18.2 0.8 0.004 16.8 0.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif COX16 PF14138.6 KFP20313.1 - 2.3 8.8 6.4 12 6.5 1.6 3.8 3 1 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Endonuclease_NS PF01223.23 KFP20316.1 - 1.4e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Exog_C PF18026.1 KFP20316.1 - 1.6e-27 95.2 0.5 3.1e-27 94.4 0.5 1.5 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain Pkinase PF00069.25 KFP20318.1 - 4.2e-31 108.3 0.0 6.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20318.1 - 6e-26 91.3 0.0 9.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.23 KFP20318.1 - 2.3e-09 38.2 14.2 2.3e-09 38.2 14.2 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KFP20318.1 - 0.00084 18.2 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Toxin_TOLIP PF00087.21 KFP20318.1 - 5.5 7.3 14.4 0.63 10.3 9.9 1.8 2 0 0 2 2 2 0 Snake toxin and toxin-like protein FGGY_C PF02782.16 KFP20322.1 - 6.5e-10 39.1 0.0 7.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Phi29_Phage_SSB PF17427.2 KFP20322.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein FGGY_N PF00370.21 KFP20323.1 - 2.3e-16 60.1 0.0 1.7e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KFP20323.1 - 2.9e-06 27.2 0.0 1.3e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3696 PF12476.8 KFP20323.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF4682 PF15733.5 KFP20324.1 - 9.5e-23 81.2 0.3 1.4e-22 80.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) Ubiquitin_5 PF18037.1 KFP20325.1 - 2.2e-34 117.7 1.2 7e-34 116.1 1.2 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain UBA PF00627.31 KFP20325.1 - 1.9e-27 94.8 0.1 1.2e-08 34.7 0.0 3.7 3 0 0 3 3 3 3 UBA/TS-N domain HOIP-UBA PF16678.5 KFP20325.1 - 8.8e-06 25.8 11.4 0.00035 20.6 1.1 4.0 2 1 1 4 4 4 2 HOIP UBA domain pair UBA_4 PF14555.6 KFP20325.1 - 3.3e-05 23.6 0.1 0.19 11.6 0.1 3.5 3 0 0 3 3 3 1 UBA-like domain TPR_12 PF13424.6 KFP20325.1 - 0.00067 19.9 8.3 1.5 9.1 2.7 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat ubiquitin PF00240.23 KFP20325.1 - 0.0012 18.5 1.5 0.0057 16.4 0.6 2.6 3 0 0 3 3 3 1 Ubiquitin family TPR_2 PF07719.17 KFP20325.1 - 0.0065 16.5 11.6 0.087 13.0 0.9 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat RuvA_C PF07499.13 KFP20325.1 - 0.0076 16.7 0.1 26 5.4 0.0 3.7 3 0 0 3 3 3 0 RuvA, C-terminal domain TPR_8 PF13181.6 KFP20325.1 - 0.026 14.7 5.3 5.8 7.4 0.3 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat Rap1_C PF11626.8 KFP20325.1 - 0.059 13.5 1.0 12 6.1 0.0 3.7 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TPR_14 PF13428.6 KFP20325.1 - 0.099 13.5 1.4 39 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP20325.1 - 0.7 9.8 6.9 6.3 6.8 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Crystall PF00030.19 KFP20328.1 - 3.9e-56 187.2 4.5 5.2e-30 103.5 0.5 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFP20328.1 - 4.6e-08 33.2 1.0 0.051 13.8 0.3 3.5 1 1 2 3 3 3 2 Interleukin-4 inducing immunoglobulin-binding domain Inhibitor_I36 PF03995.13 KFP20328.1 - 1e-05 25.4 0.1 0.005 16.7 0.0 2.6 2 1 0 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KFP20328.1 - 0.0071 16.5 0.7 0.16 12.1 0.1 2.5 2 1 0 3 3 3 1 Beta/Gamma crystallin PCSK9_C1 PF18459.1 KFP20328.1 - 0.073 13.2 0.9 0.2 11.8 0.3 1.9 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain LPD18 PF18832.1 KFP20328.1 - 0.15 12.2 0.2 1.8 8.6 0.0 2.3 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 18 WIYLD PF10440.9 KFP20328.1 - 0.21 11.4 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Ras PF00071.22 KFP20329.1 - 5.3e-43 146.4 0.4 6.2e-43 146.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20329.1 - 1.9e-13 50.7 0.0 3.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20329.1 - 8e-05 22.2 0.1 8.5e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP20329.1 - 0.00015 21.4 0.1 0.00019 21.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP20329.1 - 0.0025 17.8 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase CBS PF00571.28 KFP20330.1 - 8.2e-33 112.6 3.3 2.6e-09 37.4 0.5 4.4 4 0 0 4 4 4 4 CBS domain Cbl_N3 PF02762.14 KFP20330.1 - 0.096 12.6 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain IF-2 PF11987.8 KFP20330.1 - 0.11 12.6 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Translation-initiation factor 2 Ricin_B_lectin PF00652.22 KFP20332.1 - 2.8e-22 79.3 2.3 4.7e-22 78.6 2.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 KFP20332.1 - 8.1e-20 71.3 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 KFP20332.1 - 7.6e-05 22.3 0.1 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KFP20332.1 - 0.00044 20.2 0.0 0.98 9.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP20332.1 - 0.00083 20.0 0.2 2.6 8.9 0.0 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Rad51 PF08423.11 KFP20334.1 - 1.7e-20 73.4 0.0 2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFP20334.1 - 0.00017 21.2 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFP20334.1 - 0.0034 16.9 0.0 0.0081 15.7 0.0 1.5 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ResIII PF04851.15 KFP20334.1 - 0.05 13.6 0.0 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KFP20334.1 - 0.057 13.3 0.4 0.38 10.7 0.4 2.1 1 1 0 1 1 1 0 NACHT domain Morc6_S5 PF17942.1 KFP20334.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like AAA_33 PF13671.6 KFP20334.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Actin PF00022.19 KFP20335.1 - 2.2e-86 290.0 0.0 1.2e-51 175.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KFP20335.1 - 2e-05 23.6 0.0 0.038 12.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFP20335.1 - 0.0088 16.5 0.0 0.021 15.2 0.0 1.8 1 1 0 1 1 1 1 Cell division protein FtsA Robl_LC7 PF03259.17 KFP20335.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain DPPIV_N PF00930.21 KFP20338.1 - 2.1e-110 368.8 0.1 3.1e-110 368.3 0.1 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP20338.1 - 1.3e-36 126.1 0.2 2.5e-36 125.2 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KFP20338.1 - 1.1e-06 28.4 0.1 0.031 14.2 0.0 3.1 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.18 KFP20338.1 - 1.1e-05 25.1 0.2 6.4e-05 22.6 0.2 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family PTCB-BRCT PF12738.7 KFP20340.1 - 2.3e-55 184.4 3.1 7.3e-21 73.9 0.0 4.7 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 KFP20340.1 - 1.6e-50 169.4 2.5 2.8e-13 50.0 0.0 5.9 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFP20340.1 - 5.1e-31 106.9 0.7 2.5e-06 27.8 0.1 6.0 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFP20340.1 - 4.4e-26 90.7 0.3 2.2e-20 72.4 0.1 3.9 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KFP20340.1 - 4.9e-13 49.2 4.3 0.00025 21.3 0.0 5.6 5 1 0 5 5 5 3 DNA ligase 3 BRCT domain SCRL PF06876.12 KFP20340.1 - 0.054 13.7 0.1 0.19 11.9 0.1 1.9 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein 7tm_1 PF00001.21 KFP20342.1 - 3.5e-62 210.1 12.8 2.3e-61 207.5 12.8 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP20342.1 - 0.00011 21.9 2.7 0.00011 21.9 2.7 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx OppC_N PF12911.7 KFP20342.1 - 0.0093 15.9 1.0 0.03 14.3 0.3 2.2 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C 7tm_4 PF13853.6 KFP20342.1 - 0.056 13.2 0.7 0.089 12.5 0.2 1.6 2 0 0 2 2 2 0 Olfactory receptor INSIG PF07281.12 KFP20345.1 - 3.1e-37 128.3 4.5 3.4e-36 124.9 4.5 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) 7tm_4 PF13853.6 KFP20346.1 - 1.3e-39 136.7 12.0 1.6e-39 136.4 12.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20346.1 - 1.4e-25 90.1 20.3 3.4e-25 88.9 20.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TLV_coat PF00429.19 KFP20347.1 - 0.1 11.3 0.5 0.1 11.2 0.5 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) TILa PF12714.7 KFP20348.1 - 1.1e-16 60.5 113.6 0.011 15.6 8.0 11.1 7 3 4 11 11 11 11 TILa domain FOLN PF09289.10 KFP20348.1 - 1.1e-16 60.6 116.9 0.0069 16.5 5.5 11.5 11 0 0 11 11 11 10 Follistatin/Osteonectin-like EGF domain CD45 PF12567.8 KFP20348.1 - 2.1e-05 24.4 46.9 0.33 10.9 0.1 7.9 2 2 6 8 8 8 6 Leukocyte receptor CD45 zf_CCCH_4 PF18345.1 KFP20348.1 - 0.00023 21.1 43.2 7.4 6.8 0.1 10.8 10 0 0 10 10 10 7 Zinc finger domain DUF287 PF03384.14 KFP20348.1 - 0.34 11.3 0.7 58 4.2 0.0 4.3 6 0 0 6 6 6 0 Drosophila protein of unknown function, DUF287 FOLN PF09289.10 KFP20349.1 - 2.3e-33 114.0 127.5 0.00076 19.6 5.2 12.2 11 1 1 12 12 12 12 Follistatin/Osteonectin-like EGF domain TILa PF12714.7 KFP20349.1 - 1.2e-31 108.4 121.7 0.00094 19.1 3.4 11.2 5 5 6 11 11 11 11 TILa domain CBM_1 PF00734.18 KFP20349.1 - 0.24 11.4 72.9 5.4 7.1 0.4 12.6 11 1 0 11 11 11 0 Fungal cellulose binding domain TILa PF12714.7 KFP20350.1 - 4.5e-17 61.7 104.4 0.0038 17.1 6.5 11.0 5 5 6 11 11 11 11 TILa domain FOLN PF09289.10 KFP20350.1 - 6.8e-15 54.9 105.5 0.0022 18.2 3.2 11.9 11 2 1 12 12 12 10 Follistatin/Osteonectin-like EGF domain polyprenyl_synt PF00348.17 KFP20350.1 - 0.029 13.5 0.0 5.8 5.9 0.0 2.6 2 1 1 3 3 3 0 Polyprenyl synthetase FeThRed_A PF02941.15 KFP20350.1 - 0.076 13.2 0.0 69 3.7 0.0 4.4 5 1 1 6 6 6 0 Ferredoxin thioredoxin reductase variable alpha chain DUF2370 PF10176.9 KFP20351.1 - 4e-08 33.2 6.9 2.4e-05 24.1 2.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) Comm PF15957.5 KFP20351.1 - 0.14 12.5 0.8 0.37 11.1 0.8 1.8 1 1 0 1 1 1 0 Commissureless DUF3446 PF11928.8 KFP20351.1 - 2.7 8.4 11.4 5 7.5 11.4 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF202 PF02656.15 KFP20351.1 - 3.7 8.1 7.4 2.5 8.6 5.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Sprouty PF05210.13 KFP20352.1 - 2.2e-28 98.7 36.7 3.9e-28 97.8 36.7 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) Ins145_P3_rec PF08709.11 KFP20355.1 - 7.1e-15 54.8 0.2 7.4e-15 54.7 0.2 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Spectrin PF00435.21 KFP20360.1 - 1.1e-71 237.9 33.6 4.6e-23 81.7 8.4 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.31 KFP20360.1 - 1.2e-53 179.9 0.4 7e-27 93.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFP20360.1 - 7.2e-28 96.5 0.0 3.9e-27 94.2 0.0 2.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KFP20360.1 - 7.7e-09 34.5 1.0 0.004 16.6 0.0 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 KFP20360.1 - 1.5e-08 34.4 0.0 3.2e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_7 PF13499.6 KFP20360.1 - 1.3e-06 28.8 1.7 3.9e-06 27.2 0.4 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KFP20360.1 - 2.4e-06 27.3 3.7 4.8e-06 26.3 0.3 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP20360.1 - 8.9e-05 22.1 3.3 0.024 14.5 0.5 3.3 3 0 0 3 3 3 2 EF-hand domain IATP PF04568.12 KFP20360.1 - 0.03 14.8 5.1 0.28 11.7 0.5 3.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP EF-hand_11 PF08976.11 KFP20360.1 - 0.043 14.7 0.2 0.21 12.5 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain XisI PF08869.11 KFP20360.1 - 0.25 11.7 6.6 0.075 13.4 1.2 2.7 2 0 0 2 2 2 0 XisI protein Gal-bind_lectin PF00337.22 KFP20361.1 - 1e-73 245.1 0.2 1.2e-38 131.7 0.0 2.0 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.18 KFP20361.1 - 1.1e-05 25.2 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 WIF domain Death PF00531.22 KFP20362.1 - 1e-09 38.4 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Death domain ERO1 PF04137.15 KFP20363.1 - 2.6e-127 424.9 0.0 3.1e-127 424.6 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PspB PF06667.12 KFP20364.1 - 1.2 9.2 7.7 0.33 11.0 3.6 2.2 2 0 0 2 2 2 0 Phage shock protein B G2F PF07474.12 KFP20365.1 - 4.8e-71 238.3 0.3 4.8e-71 238.3 0.3 1.6 2 0 0 2 2 2 1 G2F domain Ldl_recept_b PF00058.17 KFP20365.1 - 1e-37 128.3 1.5 4e-10 40.0 0.1 5.5 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.7 KFP20365.1 - 5.2e-30 103.3 104.2 4.2e-09 36.5 10.8 6.6 6 0 0 6 6 6 5 EGF domain NIDO PF06119.14 KFP20365.1 - 4e-22 78.9 0.6 1.4e-21 77.2 0.6 2.1 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.15 KFP20365.1 - 2.8e-20 72.2 95.1 3.7e-09 36.6 9.4 7.0 6 0 0 6 6 6 5 Calcium-binding EGF domain Thyroglobulin_1 PF00086.18 KFP20365.1 - 5.5e-18 64.4 1.1 2.7e-17 62.2 1.1 2.3 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat cEGF PF12662.7 KFP20365.1 - 1.1e-17 63.6 50.8 2.5e-06 27.3 0.9 6.8 6 0 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP20365.1 - 9.3e-16 57.8 89.5 2.7e-08 33.9 7.1 6.6 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP20365.1 - 1.6e-11 44.3 95.9 0.00058 20.1 6.9 7.2 7 0 0 7 7 7 6 EGF-like domain EGF_MSP1_1 PF12946.7 KFP20365.1 - 2.5e-05 24.2 66.5 0.00039 20.4 1.6 5.9 6 0 0 6 6 5 3 MSP1 EGF domain 1 SGL PF08450.12 KFP20365.1 - 5.9e-05 22.8 0.0 0.00022 20.9 0.0 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region hEGF PF12661.7 KFP20365.1 - 1.3 9.8 78.2 0.031 14.9 5.2 8.2 7 1 0 7 7 6 0 Human growth factor-like EGF G-gamma PF00631.22 KFP20366.1 - 1.3e-16 60.4 0.0 1.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain Galactosyl_T PF01762.21 KFP20368.1 - 2.8e-28 99.1 0.0 3.2e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase CAP_GLY PF01302.25 KFP20369.1 - 5.5e-21 74.4 0.3 9.7e-21 73.6 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KFP20369.1 - 1.2e-13 51.0 21.2 0.0011 19.4 0.8 4.9 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP20369.1 - 2.5e-11 43.4 2.4 1.7e-08 34.2 0.4 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFP20369.1 - 8.6e-10 38.2 25.5 0.00084 19.1 8.7 5.3 3 2 1 4 4 4 4 Leucine rich repeat Ubiquitin_2 PF14560.6 KFP20369.1 - 6.7e-07 29.7 0.0 2.1e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.6 KFP20369.1 - 0.099 12.7 17.2 5.1 7.4 0.7 6.2 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 KFP20369.1 - 0.34 11.6 17.2 45 5.2 0.6 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat polyprenyl_synt PF00348.17 KFP20370.1 - 3.7e-62 209.7 0.0 5.1e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RRM_1 PF00076.22 KFP20371.1 - 1.8e-28 98.2 0.6 8.5e-15 54.3 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP20371.1 - 1.3e-07 31.7 0.1 0.012 15.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 KFP20371.1 - 0.00034 20.4 0.0 0.047 13.5 0.0 2.6 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KFP20371.1 - 0.15 12.1 0.0 6.1 6.9 0.0 2.6 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MAS20 PF02064.15 KFP20372.1 - 1.7e-27 96.0 0.4 2e-27 95.8 0.4 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor RSN1_7TM PF02714.15 KFP20372.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate TPR_1 PF00515.28 KFP20372.1 - 0.054 13.3 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP20372.1 - 0.071 14.0 0.1 0.25 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP20372.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SpoU_methylase PF00588.19 KFP20373.1 - 1.1e-29 103.5 0.0 4.5e-29 101.4 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family EamA PF00892.20 KFP20374.1 - 1.2e-07 32.0 8.7 1.2e-07 32.0 8.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 KFP20374.1 - 1.4e-05 24.8 24.6 2e-05 24.3 24.6 1.2 1 0 0 1 1 1 1 Solute carrier family 35 Ion_trans_2 PF07885.16 KFP20378.1 - 7.5e-32 109.1 20.4 1.4e-16 60.2 2.9 3.1 3 0 0 3 3 3 2 Ion channel RVT_1 PF00078.27 KFP20381.1 - 4.6e-23 81.9 0.0 7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP20381.1 - 1.3e-05 25.1 0.1 3.5e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 KFP20382.1 - 2e-31 109.2 0.0 4.2e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP20382.1 - 5.8e-26 91.4 0.0 1.3e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3552 PF12072.8 KFP20382.1 - 0.19 11.1 14.6 0.35 10.2 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.14 KFP20382.1 - 1.5 9.1 10.8 4.6 7.6 10.8 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 KFP20382.1 - 3.6 6.8 10.8 6.3 6.0 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pecanex_C PF05041.15 KFP20384.1 - 2e-114 380.9 0.0 3.1e-114 380.3 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) PRRSV_2b PF07069.11 KFP20384.1 - 0.15 12.6 1.4 0.8 10.3 1.4 2.2 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b NTPase_1 PF03266.15 KFP20385.1 - 6.1e-56 188.9 0.1 6.8e-56 188.8 0.1 1.0 1 0 0 1 1 1 1 NTPase AAA PF00004.29 KFP20385.1 - 0.021 15.3 0.1 0.079 13.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFP20385.1 - 0.04 13.6 0.1 0.14 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFP20385.1 - 0.042 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KFP20385.1 - 0.076 13.0 0.0 9.8 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFP20385.1 - 0.11 12.5 0.1 1.6 8.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFP20385.1 - 0.15 12.3 0.0 0.49 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain HPHLAWLY PF14925.6 KFP20386.1 - 4.5e-71 240.4 32.4 2.6e-67 228.0 25.9 3.3 1 1 1 2 2 2 2 Domain of unknown function SPAR_C PF11881.8 KFP20389.1 - 6.1e-71 239.1 0.1 2.2e-70 237.3 0.1 2.0 1 0 0 1 1 1 1 C-terminal domain of SPAR protein Rap_GAP PF02145.15 KFP20389.1 - 4.9e-67 225.1 0.0 1e-66 224.0 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP PDZ_6 PF17820.1 KFP20389.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KFP20389.1 - 2.4e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain bZIP_2 PF07716.15 KFP20389.1 - 0.33 11.1 4.8 1.5 9.0 4.8 2.2 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KFP20389.1 - 5.8 6.8 5.5 13 5.6 5.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Translin PF01997.16 KFP20390.1 - 5e-62 209.5 0.1 6.2e-62 209.2 0.1 1.1 1 0 0 1 1 1 1 Translin family 2OG-FeII_Oxy_3 PF13640.6 KFP20391.1 - 1.4e-21 77.2 0.0 2.1e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFP20391.1 - 8.1e-11 42.4 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP20391.1 - 0.00043 20.7 0.0 0.00064 20.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SprT-like PF10263.9 KFP20392.1 - 8.2e-21 74.0 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Aminopep PF10023.9 KFP20392.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative aminopeptidase Ras PF00071.22 KFP20393.1 - 2.4e-26 92.3 0.0 2.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20393.1 - 1.2e-06 28.7 0.0 3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Lipase_GDSL_3 PF14606.6 KFP20393.1 - 0.0019 18.4 0.0 0.0023 18.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SLBP_RNA_bind PF15247.6 KFP20393.1 - 0.069 13.3 1.4 0.17 12.0 0.4 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Abhydrolase_2 PF02230.16 KFP20393.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ras PF00071.22 KFP20395.1 - 3.2e-59 199.1 0.2 3.7e-59 199.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20395.1 - 3.1e-33 114.6 0.1 4.2e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20395.1 - 3.5e-14 52.6 0.1 4.4e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP20395.1 - 4.8e-06 26.2 0.1 0.00033 20.3 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP20395.1 - 8.4e-05 22.6 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP20395.1 - 0.00083 18.8 0.0 0.001 18.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFP20395.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KFP20395.1 - 0.002 18.0 0.2 0.93 9.4 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFP20395.1 - 0.0063 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KFP20395.1 - 0.0081 15.9 0.1 0.026 14.3 0.0 1.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFP20395.1 - 0.023 15.0 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP20395.1 - 0.032 14.6 0.0 0.044 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KFP20395.1 - 0.036 13.8 0.0 3.6 7.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 KFP20395.1 - 0.052 12.9 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 KaiC Septin PF00735.18 KFP20395.1 - 0.061 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KFP20395.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KFP20395.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFP20395.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KFP20395.1 - 0.12 12.8 0.2 0.94 9.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CCSAP PF15748.5 KFP20396.1 - 6.6e-53 180.5 24.1 7.3e-53 180.3 24.1 1.0 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated Actin PF00022.19 KFP20398.1 - 3.6e-150 500.1 0.0 1.2e-149 498.4 0.0 1.7 1 1 0 1 1 1 1 Actin Nucleoporin_C PF03177.14 KFP20399.1 - 2.9e-27 95.7 9.4 2.1e-26 92.9 9.4 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KFP20399.1 - 1.3e-10 40.6 0.3 2.3e-10 39.8 0.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DYW_deaminase PF14432.6 KFP20399.1 - 0.1 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases ABC_membrane PF00664.23 KFP20400.1 - 3.7e-59 200.6 5.3 5.3e-59 200.1 5.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP20400.1 - 1.4e-33 116.3 0.0 2.9e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP20400.1 - 2.3e-07 30.5 0.1 5.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KFP20400.1 - 0.00061 20.2 0.2 0.0098 16.3 0.2 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFP20400.1 - 0.0014 19.1 0.4 0.0053 17.2 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFP20400.1 - 0.0023 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KFP20400.1 - 0.0028 16.5 0.1 0.051 12.4 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KFP20400.1 - 0.0029 17.2 0.0 0.0072 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFP20400.1 - 0.0032 17.7 0.2 0.024 14.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFP20400.1 - 0.013 15.5 0.2 0.096 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KFP20400.1 - 0.013 15.3 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFP20400.1 - 0.021 14.5 0.1 0.08 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFP20400.1 - 0.022 14.7 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KFP20400.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFP20400.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFP20400.1 - 0.16 12.5 0.0 0.48 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFP20400.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 KFP20402.1 - 1.5e-53 177.5 6.1 5.5e-10 39.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFP20402.1 - 8.2e-31 106.9 3.9 1.4e-30 106.2 3.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFP20402.1 - 1.4e-12 47.7 0.0 0.0033 17.7 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP20402.1 - 4.2e-05 22.4 0.4 0.51 8.9 0.1 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFP20402.1 - 0.00074 18.6 0.0 0.15 11.0 0.0 3.4 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP20402.1 - 0.0013 18.2 0.0 2.2 7.5 0.0 3.2 1 1 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 KFP20402.1 - 0.0046 16.9 0.0 0.048 13.5 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFP20402.1 - 0.066 12.5 0.0 0.36 10.1 0.0 2.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DDE_Tnp_1_7 PF13843.6 KFP20404.1 - 2.7e-83 280.2 0.5 3.1e-83 280.0 0.5 1.0 1 0 0 1 1 1 1 Transposase IS4 HEPN PF05168.14 KFP20404.1 - 0.045 13.9 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 HEPN domain DUF3510 PF12022.8 KFP20406.1 - 6.6e-40 136.4 1.5 1e-39 135.8 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KFP20406.1 - 2.4e-37 128.0 3.4 2.4e-37 128.0 3.4 3.2 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KFP20406.1 - 9.2e-05 22.4 0.6 0.0021 18.1 0.1 2.9 2 0 0 2 2 2 1 Vps51/Vps67 DUF1664 PF07889.12 KFP20406.1 - 0.0052 16.8 3.6 0.077 13.0 0.7 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFP20406.1 - 0.015 15.4 1.7 4.5 7.3 0.0 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.9 KFP20406.1 - 0.2 11.9 6.2 0.9 9.7 0.4 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF4795 PF16043.5 KFP20406.1 - 2.3 7.8 5.4 1.9 8.0 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 KFP20406.1 - 3.8 7.5 5.3 18 5.3 0.2 3.5 3 2 1 4 4 4 0 Laminin Domain II Serpin PF00079.20 KFP20407.1 - 8.2e-56 189.9 0.0 1.1e-55 189.5 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Hydantoinase_A PF01968.18 KFP20407.1 - 0.17 11.2 0.0 0.36 10.0 0.0 1.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Peptidase_C2 PF00648.21 KFP20408.1 - 8e-131 435.5 0.0 1.4e-130 434.7 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP20408.1 - 2e-49 167.5 0.0 3.4e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KFP20408.1 - 1.1e-11 43.4 1.9 7.1e-06 25.2 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP20408.1 - 4.9e-10 38.5 0.3 0.0005 19.8 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFP20408.1 - 4.9e-08 32.7 0.3 6.9e-06 25.8 0.1 3.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KFP20408.1 - 0.0001 22.7 3.3 0.068 13.6 0.4 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP20408.1 - 0.00015 21.1 0.3 0.014 14.9 0.0 2.8 2 0 0 2 2 2 1 EF hand Ndufs5 PF10200.9 KFP20408.1 - 0.026 14.8 0.3 0.75 10.1 0.0 3.0 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Stb3 PF10330.9 KFP20408.1 - 0.16 12.0 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 Putative Sin3 binding protein Arv1 PF04161.13 KFP20410.1 - 5.9e-49 167.1 4.2 6.9e-49 166.9 4.2 1.0 1 0 0 1 1 1 1 Arv1-like family SPRY PF00622.28 KFP20411.1 - 2.6e-12 46.9 0.0 4.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KFP20411.1 - 3.4e-09 36.7 4.3 9.2e-09 35.3 4.3 1.8 1 0 0 1 1 1 1 B-box zinc finger fn3 PF00041.21 KFP20411.1 - 8e-09 35.7 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.6 KFP20411.1 - 1.4e-05 24.6 0.1 3.4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 SPRY-associated domain Laminin_G_3 PF13385.6 KFP20411.1 - 0.011 15.9 0.5 0.042 14.0 0.3 2.0 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily zf-UBR PF02207.20 KFP20411.1 - 0.053 13.7 4.2 0.16 12.2 4.2 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF1281 PF06924.11 KFP20411.1 - 0.11 12.0 0.4 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4602 PF15375.6 KFP20412.1 - 2.7e-20 73.1 13.5 2.9e-20 72.9 13.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Acyltransferase PF01553.21 KFP20413.1 - 1e-22 80.2 0.0 1.9e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TBP PF00352.21 KFP20414.1 - 3.5e-64 212.8 0.4 3.3e-32 110.3 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFP20414.1 - 0.00048 20.2 0.6 1.5 9.0 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) Proteasome PF00227.26 KFP20415.1 - 1.6e-38 132.1 0.1 2e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.15 KFP20415.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C1 family DUF4209 PF13910.6 KFP20418.1 - 2.8e-29 101.2 0.1 2.8e-23 81.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Tctex-1 PF03645.13 KFP20419.1 - 2.5e-22 79.1 0.6 3.1e-22 78.8 0.6 1.0 1 0 0 1 1 1 1 Tctex-1 family PHD PF00628.29 KFP20420.1 - 4.9e-17 61.6 25.1 1e-08 34.9 10.6 2.4 1 1 1 2 2 2 2 PHD-finger PHD_4 PF16866.5 KFP20420.1 - 0.0019 18.2 9.5 0.0019 18.2 9.5 3.2 1 1 1 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFP20420.1 - 0.014 15.0 4.7 0.014 15.0 4.7 2.7 2 1 0 2 2 2 0 PHD-finger Herpes_MCP PF03122.14 KFP20420.1 - 0.036 11.6 0.2 0.047 11.1 0.2 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein Zf_RING PF16744.5 KFP20420.1 - 4.3 7.5 22.0 3 8.0 9.4 3.2 1 1 1 2 2 2 0 KIAA1045 RING finger zf-PHD-like PF15446.6 KFP20420.1 - 5.1 6.7 18.2 3.8 7.1 4.7 3.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain UPF0669 PF17065.5 KFP20421.1 - 1.3e-108 360.8 0.2 1.4e-108 360.7 0.2 1.0 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 Glycos_transf_2 PF00535.26 KFP20424.1 - 1.6e-08 34.6 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP20426.1 - 2.4e-25 89.2 0.6 3.2e-25 88.8 0.6 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 KFP20426.1 - 1.3e-16 60.9 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 KFP20426.1 - 7.7e-06 25.5 0.3 1.8e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP20426.1 - 0.0052 16.3 0.0 0.036 13.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFP20427.1 - 3.9e-25 88.6 0.0 6.7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP20427.1 - 7.3e-23 81.2 1.2 1.3e-22 80.4 1.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP20427.1 - 4.9e-05 23.3 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KFP20427.1 - 0.00068 19.2 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KFP20427.1 - 0.0093 15.5 0.1 0.061 12.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HMG_box PF00505.19 KFP20428.1 - 1.8e-33 114.8 10.6 7.4e-26 90.4 1.5 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP20428.1 - 9.6e-30 103.0 10.7 8.7e-15 55.1 0.9 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 KFP20428.1 - 0.0024 17.8 11.5 0.22 11.5 1.2 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Nucleo_P87 PF07267.11 KFP20428.1 - 0.24 10.2 7.0 0.22 10.4 7.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 YABBY PF04690.13 KFP20428.1 - 2.3 8.7 5.6 0.51 10.9 0.7 2.0 1 1 1 2 2 2 0 YABBY protein SAP30_Sin3_bdg PF13867.6 KFP20429.1 - 2.5e-23 82.1 0.1 3.9e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.6 KFP20429.1 - 2.6e-13 49.9 1.3 6.1e-13 48.7 1.2 1.7 2 0 0 2 2 2 1 SAP30 zinc-finger SCRG1 PF15224.6 KFP20430.1 - 1.2e-48 163.1 5.6 1.4e-48 162.9 5.6 1.0 1 0 0 1 1 1 1 Scrapie-responsive protein 1 Sec7 PF01369.20 KFP20432.1 - 1.1e-39 136.1 0.1 1.5e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 KFP20432.1 - 3.2e-07 30.1 0.5 8.4e-07 28.8 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP20432.1 - 0.004 17.0 1.1 0.0092 15.8 0.1 2.0 2 0 0 2 2 2 1 F-box domain CEP44 PF15007.6 KFP20433.1 - 1.8e-52 176.8 0.9 5.2e-52 175.3 0.5 2.0 2 0 0 2 2 2 1 Centrosomal spindle body, CEP44 LELP1 PF15042.6 KFP20433.1 - 0.96 9.9 4.6 0.44 10.9 1.3 2.1 2 1 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 adh_short PF00106.25 KFP20434.1 - 3.9e-46 157.0 0.0 4.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP20434.1 - 1.1e-38 133.1 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP20434.1 - 3.9e-07 30.2 0.0 5.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFP20434.1 - 0.031 13.7 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glycos_transf_3 PF00591.21 KFP20434.1 - 0.29 10.7 1.3 0.51 9.9 0.3 1.7 2 0 0 2 2 2 0 Glycosyl transferase family, a/b domain Granulin PF00396.18 KFP20435.1 - 1.1e-52 176.1 141.6 2.4e-18 66.2 20.7 8.8 8 1 1 9 9 9 7 Granulin GCIP PF13324.6 KFP20436.1 - 2.7e-07 30.5 0.0 3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting FAM163 PF15069.6 KFP20436.1 - 0.00075 20.0 0.1 0.00082 19.9 0.1 1.2 1 0 0 1 1 1 1 FAM163 family Cadherin_C_2 PF16492.5 KFP20436.1 - 0.0079 16.9 0.2 0.011 16.5 0.1 1.4 1 1 0 1 1 1 1 Cadherin cytoplasmic C-terminal RhoGAP PF00620.27 KFP20437.1 - 4.8e-35 120.6 0.0 6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain zf-RING_9 PF13901.6 KFP20438.1 - 5.3e-58 196.4 4.6 8.8e-58 195.7 4.6 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon PH PF00169.29 KFP20438.1 - 4e-09 36.9 0.0 7.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 PH domain zf-RRN7 PF11781.8 KFP20438.1 - 0.0096 15.6 3.3 0.5 10.1 1.6 2.7 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PH_13 PF16652.5 KFP20438.1 - 0.017 15.0 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain FYVE_2 PF02318.16 KFP20438.1 - 2.9 8.1 6.2 4.5 7.5 1.4 2.7 2 1 0 2 2 2 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 KFP20438.1 - 3.6 7.8 9.9 2.2 8.5 0.6 3.5 3 1 1 4 4 4 0 Prokaryotic RING finger family 2 RUN PF02759.19 KFP20439.1 - 1.2e-11 44.7 0.1 2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 RUN domain Rad52_Rad22 PF04098.15 KFP20440.1 - 5.3e-10 39.4 0.1 6.7e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 KFP20440.1 - 5.5e-06 26.1 0.1 3.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP20440.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hormone_1 PF00103.20 KFP20441.1 - 6.3e-15 55.5 0.0 6.8e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family TRAPP PF04051.16 KFP20442.1 - 2.3e-36 124.7 0.0 2.7e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component 7tm_4 PF13853.6 KFP20443.1 - 1.3e-41 143.2 12.2 1.4e-41 143.1 12.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20443.1 - 3.8e-25 88.7 17.8 5.1e-25 88.3 17.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP20443.1 - 0.015 14.9 10.9 0.023 14.3 10.8 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP20444.1 - 2.1e-48 165.5 13.4 2.4e-48 165.3 13.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20444.1 - 5.1e-30 104.7 15.8 6.7e-30 104.3 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP20445.1 - 6.1e-44 150.8 13.1 7.3e-44 150.6 13.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20445.1 - 1.9e-27 96.3 12.6 2.6e-27 95.8 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP20445.1 - 0.12 12.0 12.0 0.18 11.4 11.7 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx LRR_8 PF13855.6 KFP20447.1 - 2.3e-54 181.0 57.9 1.4e-12 47.1 3.4 5.9 1 1 7 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 KFP20447.1 - 1.5e-17 63.8 0.1 1.8e-11 44.1 0.1 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP20447.1 - 8.2e-17 61.0 25.6 8.8e-06 26.0 2.0 6.7 5 2 1 7 7 7 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP20447.1 - 1.9e-16 59.9 0.0 3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP20447.1 - 1.2e-13 51.5 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP20447.1 - 6.3e-10 39.1 0.1 1.4e-09 38.0 0.0 1.6 2 0 0 2 2 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP20447.1 - 2e-07 31.2 0.0 3.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KFP20447.1 - 2.5e-06 27.3 28.5 0.38 11.5 0.0 10.6 11 1 0 11 11 10 2 Leucine Rich Repeat LRRNT PF01462.18 KFP20447.1 - 0.0038 16.8 3.5 0.0038 16.8 3.5 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain V-set PF07686.17 KFP20447.1 - 0.0042 17.2 0.1 0.16 12.2 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP20447.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain LRR_6 PF13516.6 KFP20447.1 - 0.03 14.4 23.7 1.5 9.0 0.0 8.1 10 0 0 10 10 10 0 Leucine Rich repeat LRRCT PF01463.24 KFP20447.1 - 0.043 14.4 2.2 0.45 11.2 0.1 3.8 3 1 1 4 4 4 0 Leucine rich repeat C-terminal domain LRR_9 PF14580.6 KFP20447.1 - 0.051 13.1 11.3 1.4 8.4 4.2 2.9 1 1 2 3 3 3 0 Leucine-rich repeat JSRP PF15312.6 KFP20448.1 - 2.4e-09 37.0 3.8 2.4e-09 37.0 3.8 2.7 2 2 1 3 3 3 1 Junctional sarcoplasmic reticulum protein AMH_N PF04709.12 KFP20449.1 - 1.8e-76 257.7 2.1 2.9e-60 204.2 1.3 2.1 1 1 1 2 2 2 2 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.20 KFP20449.1 - 5.9e-11 43.3 0.1 9.3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain SF3A2 PF16835.5 KFP20451.1 - 2.9e-40 136.5 0.2 4.9e-40 135.8 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFP20451.1 - 3.3e-07 30.5 2.0 3.3e-07 30.5 2.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KFP20451.1 - 0.004 17.1 0.1 0.0066 16.4 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KFP20451.1 - 0.051 13.1 3.2 0.094 12.3 3.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like LPD24 PF18839.1 KFP20451.1 - 0.22 11.8 0.7 28 5.0 0.0 2.7 3 0 0 3 3 3 0 Large polyvalent protein associated domain 24 zf-C2H2_jaz PF12171.8 KFP20451.1 - 4.9 7.6 6.7 9.9 6.6 5.1 2.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DOT1 PF08123.13 KFP20452.1 - 4.9e-83 277.7 0.4 1.4e-82 276.2 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 DUF2000 PF09391.10 KFP20452.1 - 0.69 9.8 2.4 20 5.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) HALZ PF02183.18 KFP20452.1 - 2.6 8.3 15.5 6.9 7.0 10.0 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper Mob1_phocein PF03637.17 KFP20453.1 - 4.8e-83 277.3 0.2 5.5e-83 277.1 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family PHR PF08005.12 KFP20454.1 - 5e-54 183.1 1.1 7.9e-54 182.4 1.1 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 KFP20454.1 - 6.8e-22 77.8 0.4 5.8e-20 71.6 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 KFP20454.1 - 2.8e-10 40.2 0.9 7e-09 35.7 0.2 3.0 1 1 2 3 3 3 1 BTB And C-terminal Kelch DUF4082 PF13313.6 KFP20454.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Pkinase PF00069.25 KFP20455.1 - 1.7e-23 83.4 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20455.1 - 1.2e-12 47.6 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP20455.1 - 4.2e-08 32.4 0.1 5.3e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP20455.1 - 0.13 12.1 0.1 5.6 6.8 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family SCAMP PF04144.13 KFP20456.1 - 1.2e-66 224.3 23.0 1.3e-66 224.2 23.0 1.0 1 0 0 1 1 1 1 SCAMP family DUF4051 PF13260.6 KFP20456.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) zf-C4 PF00105.18 KFP20457.1 - 2.4e-33 114.4 13.6 4.3e-33 113.6 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP20459.1 - 2.4e-34 118.7 3.6 3e-34 118.4 3.6 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ESR1_C PF12743.7 KFP20459.1 - 9e-19 67.0 2.6 1.5e-18 66.2 2.6 1.4 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal Thyroglob_assoc PF16597.5 KFP20459.1 - 0.0061 16.8 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain Spectrin PF00435.21 KFP20460.1 - 2e-137 449.3 803.9 1.6e-12 47.8 9.2 73.1 64 10 10 76 76 76 45 Spectrin repeat CH PF00307.31 KFP20460.1 - 4e-37 126.7 0.2 1.9e-20 73.0 0.0 5.9 4 0 0 4 4 4 2 Calponin homology (CH) domain KASH PF10541.9 KFP20460.1 - 2.2e-26 91.9 5.3 6e-26 90.5 5.3 1.9 1 0 0 1 1 1 1 Nuclear envelope localisation domain CAMSAP_CH PF11971.8 KFP20460.1 - 1.6e-05 24.7 0.0 0.11 12.3 0.0 3.5 2 0 0 2 2 2 2 CAMSAP CH domain TEX12 PF15219.6 KFP20460.1 - 4 7.8 13.4 1.9 8.9 0.3 6.7 6 0 0 6 6 6 0 Testis-expressed 12 Myc_target_1 PF15179.6 KFP20462.1 - 2.2e-51 174.5 11.8 1.2e-26 93.8 2.9 2.0 1 1 1 2 2 2 2 Myc target protein 1 Hormone_2 PF00123.20 KFP20463.1 - 8e-24 83.2 7.6 9.5e-12 44.6 0.2 3.0 3 0 0 3 3 3 2 Peptide hormone F-box PF00646.33 KFP20464.1 - 4.8e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain IBR PF01485.21 KFP20464.1 - 1.4e-05 25.2 11.0 3.1e-05 24.1 11.0 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain F-box-like PF12937.7 KFP20464.1 - 0.0087 15.9 0.0 0.035 14.0 0.0 2.0 1 1 1 2 2 2 1 F-box-like RGS PF00615.19 KFP20465.1 - 4.9e-36 123.6 1.0 6.7e-36 123.1 1.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1170 PF06663.13 KFP20469.1 - 3.4e-56 190.3 0.5 6.3e-56 189.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.9 KFP20469.1 - 2.3e-37 127.0 0.1 5.6e-37 125.8 0.1 1.7 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.30 KFP20469.1 - 8.8e-13 48.5 0.4 2e-12 47.3 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KFP20469.1 - 1.9e-12 47.6 0.7 3.4e-12 46.8 0.7 1.4 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 KFP20469.1 - 2.2e-10 40.7 0.2 1.4e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain SAM_2 PF07647.17 KFP20469.1 - 1.9e-08 34.3 0.5 4.1e-08 33.2 0.5 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 KFP20469.1 - 8e-07 28.8 0.4 2.6e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP20469.1 - 0.0026 18.1 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tiam_CC_Ex PF18385.1 KFP20473.1 - 8.2e-56 186.5 0.1 1.2e-55 185.9 0.1 1.3 1 0 0 1 1 1 1 T-lymphoma invasion and metastasis CC-Ex domain PH PF00169.29 KFP20473.1 - 1.6e-07 31.8 0.1 5.9e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFP20473.1 - 3.7e-06 27.3 0.1 1.1e-05 25.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KFP20473.1 - 0.008 16.0 0.1 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain Nup96 PF12110.8 KFP20473.1 - 0.018 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Nuclear protein 96 DUF4660 PF15559.6 KFP20473.1 - 0.088 13.1 0.9 0.32 11.3 0.4 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4660) Arm-DNA-bind_5 PF17293.2 KFP20473.1 - 0.089 13.2 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain RhoGEF PF00621.20 KFP20474.1 - 4.9e-27 95.3 2.5 1.1e-26 94.2 0.7 2.2 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 KFP20474.1 - 0.072 13.3 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain FadA PF09403.10 KFP20474.1 - 0.51 10.8 4.8 0.69 10.4 0.4 2.5 2 0 0 2 2 2 0 Adhesion protein FadA RrnaAD PF00398.20 KFP20475.1 - 3.1e-40 137.9 0.0 3.9e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Amelogenin PF02948.15 KFP20475.1 - 0.0034 18.1 0.1 0.0053 17.4 0.1 1.3 1 0 0 1 1 1 1 Amelogenin PMP22_Claudin PF00822.20 KFP20476.1 - 3.8e-27 95.2 9.7 6e-27 94.5 9.3 1.5 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP20476.1 - 1.7e-09 37.8 5.7 6e-08 32.7 5.3 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3185 PF11381.8 KFP20476.1 - 0.082 12.9 1.3 1.4 9.0 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) DUF872 PF05915.12 KFP20476.1 - 0.19 11.9 0.9 0.33 11.1 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4064 PF13273.6 KFP20476.1 - 8.8 6.7 11.3 12 6.2 2.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Ferric_reduct PF01794.19 KFP20477.1 - 3.8e-27 94.9 1.7 9.2e-27 93.6 1.7 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFP20477.1 - 1.1e-25 90.5 0.1 8.6e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFP20477.1 - 8.6e-19 67.6 0.1 1.9e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KFP20477.1 - 0.017 15.5 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF3648 PF12364.8 KFP20480.1 - 0.053 13.7 0.3 0.074 13.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) BAF250_C PF12031.8 KFP20481.1 - 1.3e-121 404.7 0.0 2.4e-121 403.9 0.0 1.4 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KFP20481.1 - 1.2e-17 64.3 0.0 2.9e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF1358 PF07096.11 KFP20482.1 - 1.2e-43 147.7 4.7 1.4e-43 147.5 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) DHHC PF01529.20 KFP20484.1 - 4.7e-36 123.9 7.4 4.7e-36 123.9 7.4 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Imm17 PF15562.6 KFP20484.1 - 9.2 6.2 9.2 0.78 9.7 0.1 2.6 3 0 0 3 3 3 0 Immunity protein 17 BAR_3_WASP_bdg PF10456.9 KFP20485.1 - 4.6e-113 376.5 0.6 6e-113 376.1 0.6 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KFP20485.1 - 1.5e-23 82.9 0.2 3.2e-23 81.9 0.2 1.6 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KFP20485.1 - 2.8e-09 36.4 0.4 8.3e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP20485.1 - 1e-08 34.9 0.3 2.5e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP20485.1 - 1e-07 31.5 0.1 2.1e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KFP20485.1 - 0.0095 15.5 0.0 1.5 8.3 0.1 2.4 1 1 1 2 2 2 2 Vps5 C terminal like Syja_N PF02383.18 KFP20487.1 - 5.4e-66 223.1 0.0 1.1e-65 222.1 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain DUF1866 PF08952.11 KFP20487.1 - 3e-54 182.9 0.1 6e-54 181.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.23 KFP20487.1 - 5e-14 52.4 0.0 8.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 KFP20487.1 - 0.0056 16.5 0.2 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tfb5 PF06331.12 KFP20488.1 - 2e-20 72.5 0.1 2.2e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Tub PF01167.18 KFP20489.1 - 3e-30 105.7 0.3 3.2e-24 86.0 0.2 4.0 3 1 0 3 3 3 2 Tub family ANAPC4_WD40 PF12894.7 KFP20489.1 - 2e-08 34.4 1.8 0.00053 20.2 0.1 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SOCS_box PF07525.16 KFP20489.1 - 0.00012 22.4 2.0 0.00036 20.8 2.0 1.9 1 0 0 1 1 1 1 SOCS box DUF3527 PF12043.8 KFP20489.1 - 0.079 12.5 0.1 0.079 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) MIG-14_Wnt-bd PF06664.12 KFP20491.1 - 3.1e-95 318.8 35.7 3.1e-95 318.8 35.7 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion PSII_Ycf12 PF05969.11 KFP20491.1 - 5 7.2 6.1 2.5 8.1 0.1 2.8 2 1 0 2 2 2 0 Photosystem II complex subunit Ycf12 Tctex-1 PF03645.13 KFP20492.1 - 1.7e-33 114.9 0.7 1.9e-33 114.8 0.7 1.0 1 0 0 1 1 1 1 Tctex-1 family C2 PF00168.30 KFP20493.1 - 3.7e-18 65.7 0.1 1.3e-15 57.5 0.0 2.7 3 0 0 3 3 3 2 C2 domain FYVE_2 PF02318.16 KFP20493.1 - 2.1e-17 63.4 12.5 2.1e-17 63.4 12.5 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger ERM PF00769.19 KFP20494.1 - 9e-69 232.0 41.4 9e-69 232.0 41.4 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 KFP20494.1 - 6e-28 97.1 0.3 1.9e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP20494.1 - 5.2e-27 94.6 0.4 5.2e-27 94.6 0.4 3.4 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP20494.1 - 1.8e-14 53.4 1.6 4.5e-14 52.1 0.1 2.4 3 0 0 3 3 3 1 FERM N-terminal domain RhoGAP PF00620.27 KFP20495.1 - 6.9e-41 139.6 0.5 1.8e-40 138.3 0.5 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF5427 PF10310.9 KFP20495.1 - 0.037 13.0 0.0 0.086 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Radial_spoke_3 PF06098.11 KFP20496.1 - 6.1e-126 419.5 11.5 6.8e-126 419.4 11.5 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 DUF4574 PF15141.6 KFP20496.1 - 0.49 10.3 4.7 1.2 9.1 4.7 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SET PF00856.28 KFP20497.1 - 0.0044 17.4 0.0 0.078 13.4 0.0 2.1 1 1 1 2 2 2 1 SET domain zf-C2H2 PF00096.26 KFP20497.1 - 1.7 9.2 11.0 0.72 10.4 2.0 3.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP20498.1 - 1.8e-19 68.8 55.2 0.0031 18.2 5.1 7.7 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP20498.1 - 3.3e-18 65.0 62.2 0.0012 19.2 7.8 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP20498.1 - 6.6e-15 54.8 63.3 0.00048 20.4 1.8 8.6 8 1 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP20498.1 - 1.1e-05 25.5 30.4 0.56 10.6 0.3 6.3 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFP20498.1 - 0.0012 19.1 24.6 0.099 12.9 6.3 4.0 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 KFP20498.1 - 0.037 14.4 32.5 7 7.0 0.3 4.8 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFP20498.1 - 0.072 12.9 0.1 0.072 12.9 0.1 5.5 6 0 0 6 6 6 0 zinc-finger C2H2-type Acyltransf_C PF16076.5 KFP20498.1 - 0.074 13.2 2.0 8.6 6.5 0.4 2.7 2 1 0 2 2 2 0 Acyltransferase C-terminus zf-C2H2_3rep PF18868.1 KFP20498.1 - 0.09 13.5 20.9 0.055 14.2 2.0 4.3 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFP20498.1 - 0.5 10.8 23.5 1.5 9.3 0.1 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP20498.1 - 0.6 10.2 0.0 0.6 10.2 0.0 7.3 7 0 0 7 7 7 0 C2H2-type zinc finger LTV PF04180.14 KFP20499.1 - 2e-87 294.4 19.3 3.1e-86 290.5 19.3 2.4 1 1 0 1 1 1 1 Low temperature viability protein UPF0767 PF15990.5 KFP20499.1 - 3.3 7.9 7.0 2.5 8.3 4.7 2.0 2 0 0 2 2 2 0 UPF0767 family RPEL PF02755.15 KFP20500.1 - 6.8e-28 95.5 21.9 1.3e-07 31.1 2.5 4.6 4 0 0 4 4 4 4 RPEL repeat Tail_tube PF10618.9 KFP20500.1 - 0.075 12.9 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Phage tail tube protein SieB PF14163.6 KFP20500.1 - 0.27 10.7 2.7 1.3 8.6 2.7 2.1 1 1 0 1 1 1 0 Super-infection exclusion protein B Alpha_L_fucos PF01120.17 KFP20502.1 - 1.8e-102 343.4 0.6 2.1e-102 343.2 0.6 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 KFP20502.1 - 1.6e-29 102.3 0.4 3.4e-29 101.2 0.4 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Peroxin-3 PF04882.12 KFP20503.1 - 9.9e-66 222.6 6.1 1.3e-35 123.3 0.0 3.0 1 1 2 3 3 3 3 Peroxin-3 dCMP_cyt_deam_1 PF00383.23 KFP20504.1 - 2.2e-10 40.3 0.9 3.2e-10 39.8 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFP20504.1 - 8.7e-09 35.3 0.1 1.1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KFP20504.1 - 0.0059 16.7 0.2 0.009 16.1 0.2 1.5 1 0 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 KFP20504.1 - 0.0068 16.5 0.2 0.0097 16.0 0.2 1.2 1 0 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 KFP20504.1 - 0.0086 16.2 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFP20504.1 - 0.021 14.9 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KFP20504.1 - 0.026 14.7 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 APOBEC3 Inv-AAD PF18785.1 KFP20504.1 - 0.12 12.3 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Far-17a_AIG1 PF04750.14 KFP20505.1 - 1.7e-64 216.8 10.2 2e-64 216.7 10.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein FancD2 PF14631.6 KFP20505.1 - 0.14 9.6 0.1 0.17 9.3 0.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-C2H2 PF00096.26 KFP20507.1 - 2.7e-18 65.3 27.8 0.00011 22.4 1.4 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP20507.1 - 9.5e-11 41.6 37.2 1.8e-06 28.1 1.0 5.4 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP20507.1 - 1.1e-10 41.5 23.7 0.0021 18.3 1.5 5.0 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFP20507.1 - 1.4e-09 38.0 23.8 0.07 14.0 0.4 5.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KFP20507.1 - 7.3e-05 23.0 25.4 0.0093 16.3 2.8 5.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP20507.1 - 0.00063 19.5 21.7 0.15 11.8 0.8 4.8 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KFP20507.1 - 0.065 13.9 7.2 8.2 7.1 0.4 4.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats NOA36 PF06524.12 KFP20507.1 - 0.22 10.8 23.2 0.18 11.1 14.2 2.4 2 0 0 2 2 2 0 NOA36 protein zf-C2H2_2 PF12756.7 KFP20507.1 - 0.55 10.6 18.3 0.21 11.9 4.2 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) RRN3 PF05327.11 KFP20507.1 - 4.1 5.8 7.1 7.5 5.0 7.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-Di19 PF05605.12 KFP20507.1 - 6.6 7.1 14.8 4.2 7.8 4.0 3.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding 7tm_2 PF00002.24 KFP20508.1 - 8.2e-48 162.8 16.9 8.2e-48 162.8 16.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) CUB PF00431.20 KFP20508.1 - 2.4e-24 85.8 0.0 6.4e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 CUB domain GPS PF01825.21 KFP20508.1 - 3.4e-17 62.7 2.9 1.1e-16 61.1 2.9 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pentaxin PF00354.17 KFP20508.1 - 1.2e-09 38.1 0.2 3.8e-09 36.5 0.2 1.8 1 0 0 1 1 1 1 Pentaxin family FIVAR PF07554.13 KFP20508.1 - 0.026 15.3 0.4 0.11 13.3 0.4 2.1 1 0 0 1 1 1 0 FIVAR domain CUB_2 PF02408.20 KFP20508.1 - 0.029 14.1 0.1 0.14 11.9 0.1 2.2 1 0 0 1 1 1 0 CUB-like domain Y1_Tnp PF01797.16 KFP20508.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Transposase IS200 like Vta1 PF04652.16 KFP20509.1 - 7e-40 136.3 3.2 1.4e-39 135.4 1.7 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFP20509.1 - 1.7e-18 66.0 0.6 1.7e-18 66.0 0.6 1.6 2 0 0 2 2 2 1 Vta1 C-terminal domain DAG_kinase_N PF14513.6 KFP20509.1 - 0.13 12.5 0.4 0.35 11.1 0.0 1.9 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus 7tm_1 PF00001.21 KFP20510.1 - 8e-54 182.7 12.3 9.9e-54 182.4 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP20510.1 - 3.5e-10 39.7 6.9 4.7e-10 39.3 6.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KFP20510.1 - 2.9e-08 33.4 11.4 4.1e-08 32.9 11.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3169 PF11368.8 KFP20510.1 - 0.031 13.8 0.3 0.031 13.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Cad PF03596.13 KFP20510.1 - 0.05 13.5 2.9 1.6 8.6 0.1 2.6 1 1 0 2 2 2 0 Cadmium resistance transporter 7TM_GPCR_Srw PF10324.9 KFP20510.1 - 0.19 11.0 11.5 0.35 10.1 11.5 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Taxilin PF09728.9 KFP20516.1 - 4.2e-119 397.3 73.5 8.6e-119 396.3 73.5 1.5 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF948 PF06103.11 KFP20516.1 - 0.46 10.8 9.0 2.2 8.6 0.2 3.9 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.8 KFP20516.1 - 8.6 3.7 55.4 13 3.1 55.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Headcase PF16002.5 KFP20517.1 - 4.2e-83 277.7 3.9 4.2e-83 277.7 3.9 1.7 2 0 0 2 2 2 1 Headcase protein HECA PF15353.6 KFP20517.1 - 4.3e-40 136.1 8.8 1.2e-39 134.6 8.8 1.8 1 0 0 1 1 1 1 Headcase protein family homologue VATC PF18716.1 KFP20517.1 - 4 7.4 17.3 0.83 9.6 1.2 5.2 4 1 0 4 4 4 0 Vms1-associating treble clef domain HypA PF01155.19 KFP20517.1 - 5.4 7.1 7.6 9.6 6.3 4.3 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KFP20517.1 - 7.3 6.5 10.9 5.8 6.8 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Costars PF14705.6 KFP20518.1 - 3.7e-31 107.1 0.4 4.1e-31 107.0 0.4 1.0 1 0 0 1 1 1 1 Costars DUF4061 PF13270.6 KFP20520.1 - 5.7e-32 109.9 4.3 7.9e-32 109.4 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) tRNA-synt_His PF13393.6 KFP20520.1 - 0.046 13.0 0.3 0.06 12.6 0.3 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PMP22_Claudin PF00822.20 KFP20523.1 - 6.1e-10 39.2 6.1 8.2e-10 38.8 6.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFP20523.1 - 0.00048 20.4 6.6 0.0012 19.1 6.6 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Pox_A14 PF05767.12 KFP20523.1 - 0.5 10.6 8.0 1.8 8.8 5.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PalH PF08733.10 KFP20523.1 - 0.66 8.9 5.0 0.87 8.5 5.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Claudin_2 PF13903.6 KFP20523.1 - 0.69 9.6 15.8 6.4 6.5 15.8 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP20524.1 - 7.2e-09 35.7 7.0 9.4e-09 35.4 7.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KFP20524.1 - 0.00025 21.3 5.7 0.00057 20.1 5.7 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.10 KFP20524.1 - 0.054 12.5 4.5 0.07 12.1 4.5 1.1 1 0 0 1 1 1 0 PalH/RIM21 PTR2 PF00854.21 KFP20524.1 - 0.11 11.4 9.3 0.99 8.2 2.1 2.3 1 1 1 2 2 2 0 POT family ABC2_membrane_5 PF13346.6 KFP20524.1 - 0.33 10.5 12.3 0.24 10.9 10.5 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Pox_A14 PF05767.12 KFP20524.1 - 3.5 7.9 8.1 0.51 10.5 3.9 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 zf-A20 PF01754.16 KFP20526.1 - 3.1e-34 116.5 67.9 1.5e-08 34.4 2.9 6.8 7 0 0 7 7 7 6 A20-like zinc finger OTU PF02338.19 KFP20526.1 - 3.1e-30 105.3 0.0 9.6e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease HLH PF00010.26 KFP20528.1 - 2.1e-12 46.8 0.3 3.9e-12 45.9 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tissue_fac PF01108.17 KFP20530.1 - 3.5e-17 62.2 0.2 4e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 Tissue factor Tissue_fac PF01108.17 KFP20531.1 - 5.7e-34 116.2 0.3 9.5e-34 115.5 0.3 1.3 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP20531.1 - 1.1e-18 67.5 0.2 2.4e-18 66.4 0.1 1.6 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KFP20531.1 - 0.022 15.1 2.4 1.5 9.3 0.6 3.2 3 1 0 3 3 3 0 Fibronectin type III domain Tissue_fac PF01108.17 KFP20532.1 - 5.4e-26 90.5 0.2 1.7e-25 88.9 0.2 1.9 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.10 KFP20532.1 - 2.3e-20 72.8 0.5 2.2e-19 69.7 0.1 2.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III EamA PF00892.20 KFP20533.1 - 0.013 15.7 11.3 0.015 15.4 11.3 1.1 1 0 0 1 1 1 0 EamA-like transporter family DUF2070 PF09843.9 KFP20533.1 - 0.13 10.5 5.3 0.17 10.1 5.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NnrU PF07298.11 KFP20533.1 - 0.13 11.7 1.5 0.18 11.3 1.0 1.5 1 1 0 1 1 1 0 NnrU protein DUF4199 PF13858.6 KFP20533.1 - 1.3 9.4 9.9 0.33 11.3 3.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) 7TMR-DISM_7TM PF07695.11 KFP20533.1 - 5.8 6.7 10.8 0.43 10.4 4.0 1.7 1 1 0 2 2 2 0 7TM diverse intracellular signalling WD40 PF00400.32 KFP20535.1 - 6.7e-23 80.5 14.3 3.8e-06 27.5 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 KFP20535.1 - 8.4e-05 22.5 0.1 0.00087 19.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KFP20535.1 - 0.022 15.1 0.6 1.6 9.1 0.2 3.1 1 1 4 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4071 PF13281.6 KFP20536.1 - 6.4e-156 519.0 1.5 6.8e-156 518.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 KFP20536.1 - 7.9e-64 215.6 0.0 2.2e-63 214.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20536.1 - 3.9e-42 144.3 0.0 6.6e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP20536.1 - 0.00045 19.1 0.0 0.001 18.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFP20536.1 - 0.0024 17.2 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like MAP7 PF05672.11 KFP20539.1 - 4.3e-43 146.8 83.4 4.3e-43 146.8 83.4 3.2 3 0 0 3 3 3 2 MAP7 (E-MAP-115) family VacA PF02691.15 KFP20540.1 - 0.0036 15.3 0.0 0.0037 15.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolating cyotoxin THRAP3_BCLAF1 PF15440.6 KFP20541.1 - 2.5e-188 628.3 103.9 2.5e-188 628.3 103.9 2.5 2 1 1 3 3 3 1 THRAP3/BCLAF1 family GRP PF07172.11 KFP20541.1 - 0.67 10.7 15.8 0.035 14.8 5.2 3.7 2 1 0 2 2 2 0 Glycine rich protein family Mito_fiss_reg PF05308.11 KFP20542.1 - 2e-76 257.4 0.4 2.5e-76 257.0 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator PDEase_I PF00233.19 KFP20543.1 - 6.4e-76 255.2 0.6 8.5e-76 254.8 0.6 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase WD40 PF00400.32 KFP20545.1 - 1.4e-24 85.8 7.5 1.7e-08 35.0 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat SH3_1 PF00018.28 KFP20545.1 - 3.2e-17 61.9 0.1 8.6e-17 60.5 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP20545.1 - 7.4e-14 51.3 0.0 1.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP20545.1 - 1.5e-11 43.8 0.0 3.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain ANAPC4_WD40 PF12894.7 KFP20545.1 - 9.6e-09 35.4 0.0 0.17 12.2 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4648 PF15505.6 KFP20545.1 - 1.9e-07 31.8 0.0 5.9e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4648) Cmyb_C PF09316.10 KFP20546.1 - 1.1e-77 259.4 2.7 1.9e-77 258.6 2.7 1.4 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFP20546.1 - 1.3e-51 172.6 20.4 9e-18 64.2 2.0 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP20546.1 - 1.3e-40 137.4 16.8 1.4e-17 63.6 1.9 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.12 KFP20546.1 - 1e-26 92.2 0.6 2e-26 91.2 0.6 1.6 1 0 0 1 1 1 1 LMSTEN motif Myb_DNA-bind_7 PF15963.5 KFP20546.1 - 6.6e-09 35.6 8.5 0.00035 20.4 0.1 3.9 2 1 2 4 4 4 2 Myb DNA-binding like SLIDE PF09111.10 KFP20546.1 - 8.7e-07 29.0 0.3 0.9 9.6 0.0 4.0 2 1 2 4 4 4 3 SLIDE SANT_DAMP1_like PF16282.5 KFP20546.1 - 0.00013 22.1 3.6 0.39 10.9 0.0 3.4 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 KFP20546.1 - 0.097 12.9 0.1 38 4.6 0.0 3.4 3 0 0 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.8 KFP20546.1 - 0.12 12.5 8.2 2.3 8.4 0.4 3.4 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 KFP20546.1 - 0.49 10.5 2.9 0.81 9.8 0.0 2.8 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GTP_EFTU PF00009.27 KFP20547.1 - 7.4e-48 162.7 0.0 1.4e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFP20547.1 - 1.6e-30 105.7 0.9 7.2e-30 103.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 KFP20547.1 - 1.1e-20 73.7 0.2 2.4e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 KFP20547.1 - 4e-07 30.3 0.1 1.4e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFP20547.1 - 8e-07 29.1 0.9 6.9e-05 22.9 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP20547.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF1296 PF06972.11 KFP20547.1 - 0.079 13.1 0.3 0.24 11.6 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) AAA_29 PF13555.6 KFP20547.1 - 0.7 9.7 2.3 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain Aldedh PF00171.22 KFP20548.1 - 1.3e-170 567.9 0.0 1.5e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFP20548.1 - 0.077 12.4 0.0 0.53 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) 120_Rick_ant PF12574.8 KFP20548.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Sugar_tr PF00083.24 KFP20552.1 - 1.6e-102 343.7 26.3 9.1e-78 262.1 14.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFP20552.1 - 1.5e-31 109.7 33.4 1.3e-27 96.6 20.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KFP20552.1 - 0.044 13.6 2.3 0.4 10.5 0.0 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 TBP PF00352.21 KFP20553.1 - 1.7e-43 146.4 0.2 5.8e-23 80.7 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFP20553.1 - 0.006 16.7 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3378) HLH PF00010.26 KFP20554.1 - 7.7e-16 57.8 0.2 1.1e-15 57.3 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hydrolase PF00702.26 KFP20555.1 - 6.3e-07 29.9 0.0 8.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.26 KFP20557.1 - 4.4e-30 103.3 1.9 5.4e-30 103.0 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1 PF07690.16 KFP20558.1 - 3.8e-38 131.3 69.3 8.8e-24 84.1 35.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP20558.1 - 0.00069 18.6 25.0 0.013 14.3 3.8 3.4 1 1 1 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 KFP20558.1 - 0.0038 16.1 14.0 0.14 10.9 0.3 2.3 1 1 1 2 2 2 2 LacY proton/sugar symporter DUF4112 PF13430.6 KFP20558.1 - 0.95 9.8 4.1 4.6 7.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) CN_hydrolase PF00795.22 KFP20560.1 - 5.6e-16 58.7 0.0 8.5e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KFP20561.1 - 8.8e-22 77.7 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KFP20562.1 - 1.1e-21 77.3 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sec10 PF07393.11 KFP20562.1 - 0.21 10.0 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 7tm_1 PF00001.21 KFP20563.1 - 1.9e-61 207.7 16.1 2.7e-61 207.2 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP20563.1 - 1.2e-06 28.1 20.7 1.2e-06 28.1 20.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP20563.1 - 4.1e-05 23.4 18.8 4.1e-05 23.4 18.8 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Kinocilin PF15033.6 KFP20563.1 - 1.1 8.9 3.6 0.91 9.2 0.3 2.4 2 0 0 2 2 2 0 Kinocilin protein Syntaxin_2 PF14523.6 KFP20565.1 - 1.8e-29 102.1 15.9 1.6e-28 99.0 9.5 2.1 2 0 0 2 2 2 2 Syntaxin-like protein Syntaxin PF00804.25 KFP20565.1 - 1.5e-11 44.4 11.6 6.3e-11 42.3 11.6 1.9 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFP20565.1 - 4.5e-09 36.2 2.7 1.3e-08 34.7 2.7 1.8 1 0 0 1 1 1 1 SNARE domain DASH_Dad4 PF08650.10 KFP20565.1 - 0.03 14.3 4.0 0.38 10.8 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad4 Cep57_CLD_2 PF14197.6 KFP20565.1 - 0.031 14.4 4.7 0.77 9.9 0.2 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 T3SS_needle_E PF08988.10 KFP20565.1 - 0.54 10.4 0.1 0.54 10.4 0.1 3.9 4 1 1 5 5 5 0 Type III secretion system, cytoplasmic E component of needle FUSC PF04632.12 KFP20565.1 - 0.6 8.6 4.0 0.64 8.5 3.6 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 KFP20565.1 - 0.77 8.3 7.3 0.26 9.8 1.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A 4HB_MCP_1 PF12729.7 KFP20565.1 - 1.6 8.2 11.3 0.43 10.1 3.6 2.5 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction IZUMO PF15005.6 KFP20565.1 - 1.8 9.1 6.0 1.9 9.0 2.1 2.4 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CCDC-167 PF15188.6 KFP20565.1 - 2.2 8.7 13.6 0.094 13.1 1.7 3.5 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF2203 PF09969.9 KFP20565.1 - 4.7 8.0 10.4 1.8 9.3 1.1 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ABC_tran_CTD PF16326.5 KFP20565.1 - 6.8 7.0 18.6 8.3 6.7 1.2 4.3 2 2 1 4 4 4 0 ABC transporter C-terminal domain DUF4446 PF14584.6 KFP20565.1 - 7.1 6.6 6.6 19 5.2 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) OmpH PF03938.14 KFP20565.1 - 7.3 6.9 21.0 0.34 11.2 9.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Enkurin PF13864.6 KFP20565.1 - 9.6 6.7 10.6 3.3 8.2 3.5 2.7 2 2 0 2 2 2 0 Calmodulin-binding Cu2_monooxygen PF01082.20 KFP20566.1 - 1.1e-49 168.0 1.2 2.3e-49 167.0 1.2 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 KFP20566.1 - 9.9e-43 145.4 0.0 1.9e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 KFP20566.1 - 2.5e-12 47.1 0.3 4.6e-12 46.2 0.3 1.4 1 0 0 1 1 1 1 DOMON domain Cys_knot PF00007.22 KFP20568.1 - 1.5e-16 60.6 9.7 1.5e-16 60.6 9.7 2.8 3 1 0 3 3 3 1 Cystine-knot domain VWC PF00093.18 KFP20568.1 - 4e-08 33.4 8.6 4e-08 33.4 8.6 3.9 2 1 1 3 3 3 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFP20568.1 - 7.9e-06 26.0 6.6 7.9e-06 26.0 6.6 2.9 2 1 0 2 2 2 1 Thrombospondin type 1 domain Phosphodiest PF01663.22 KFP20569.1 - 6.3e-86 289.2 0.0 8.3e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFP20569.1 - 3.2e-15 56.2 46.0 2.2e-08 34.4 14.6 3.0 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFP20569.1 - 1.1e-07 31.9 0.1 2.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.23 KFP20569.1 - 0.00035 20.1 0.0 0.016 14.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP20570.1 - 7.4e-82 275.8 0.1 9.9e-82 275.4 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 KFP20570.1 - 1.1e-16 60.9 37.7 2.6e-08 34.1 15.1 2.7 2 0 0 2 2 2 2 Somatomedin B domain Endonuclease_NS PF01223.23 KFP20570.1 - 4e-13 49.7 0.1 9.1e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Metalloenzyme PF01676.18 KFP20570.1 - 2.5e-05 23.8 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFP20570.1 - 0.003 17.0 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 Sulfatase Med23 PF11573.8 KFP20572.1 - 0 2025.9 9.9 0 2025.7 9.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 AKAP7_RIRII_bdg PF10470.9 KFP20573.1 - 1.8e-35 120.8 4.4 3.2e-35 120.0 4.4 1.4 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein AKAP7_NLS PF10469.9 KFP20573.1 - 5.5e-28 98.3 0.6 8.5e-28 97.7 0.6 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KFP20573.1 - 6.4e-05 22.9 0.1 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.12 KFP20573.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein LPD3 PF18798.1 KFP20573.1 - 0.076 13.3 0.6 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 HU-CCDC81_euk_2 PF18289.1 KFP20573.1 - 0.19 11.9 0.9 4.6 7.5 0.0 2.5 3 0 0 3 3 3 0 CCDC81 eukaryotic HU domain 2 MutS_V PF00488.21 KFP20574.1 - 1e-48 165.8 0.0 2.1e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFP20574.1 - 6.5e-25 88.5 0.3 1.2e-24 87.6 0.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KFP20574.1 - 6.4e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 KFP20574.1 - 0.09 12.8 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KFP20574.1 - 0.47 9.9 1.3 4.2 6.7 0.1 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain 4_1_CTD PF05902.13 KFP20575.1 - 5.5e-32 110.0 7.1 5.5e-32 110.0 7.1 3.1 3 0 0 3 3 3 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFP20575.1 - 1.1e-24 86.6 0.0 2.5e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAB PF04382.13 KFP20575.1 - 1.1e-23 83.0 1.9 5.4e-23 80.8 1.9 2.3 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFP20575.1 - 4.9e-20 72.1 2.4 3.8e-19 69.2 0.1 3.0 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP20575.1 - 1.1e-19 70.1 0.5 3.2e-19 68.6 0.3 2.0 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFP20575.1 - 1.4e-17 63.5 4.5 1.4e-17 63.5 4.5 2.5 2 0 0 2 2 2 1 FERM adjacent (FA) SR-25 PF10500.9 KFP20575.1 - 0.0078 15.9 8.8 0.0078 15.9 8.8 3.3 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2371 PF10177.9 KFP20576.1 - 7e-61 204.5 0.1 1.4e-60 203.5 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 KFP20576.1 - 0.049 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Neurensin RbcS PF12338.8 KFP20576.1 - 0.084 13.1 0.3 0.33 11.2 0.3 2.1 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit She9_MDM33 PF05546.11 KFP20576.1 - 0.092 12.5 0.0 0.38 10.5 0.0 1.9 1 1 1 2 2 2 0 She9 / Mdm33 family DUF202 PF02656.15 KFP20576.1 - 0.1 13.0 0.1 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SAM_1 PF00536.30 KFP20578.1 - 2.6e-11 43.8 0.3 6.9e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP20578.1 - 1.6e-08 34.5 0.0 5e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RPM2 PF08579.11 KFP20578.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.4 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) SAM_Ste50p PF09235.10 KFP20578.1 - 0.13 12.5 0.3 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif MBT PF02820.18 KFP20580.1 - 6.6e-95 311.5 5.9 1.7e-31 108.3 0.1 3.1 3 0 0 3 3 3 3 mbt repeat Calci_bind_CcbP PF11535.8 KFP20580.1 - 0.043 14.3 0.0 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 Calcium binding HapK PF11639.8 KFP20580.1 - 0.043 14.3 0.1 50 4.4 0.0 3.2 3 0 0 3 3 3 0 REDY-like protein HapK DUF2577 PF10844.8 KFP20580.1 - 0.2 11.9 0.1 17 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Tudor-knot PF11717.8 KFP20580.1 - 0.43 10.5 4.5 3.3 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain SWIRM-assoc_2 PF16496.5 KFP20580.1 - 0.52 9.1 4.3 3 6.6 0.2 2.4 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal SYS1 PF09801.9 KFP20581.1 - 2.9e-06 27.5 18.4 3.9e-06 27.1 18.4 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network RhoGAP PF00620.27 KFP20582.1 - 1.7e-41 141.6 1.8 1.7e-41 141.6 1.8 2.5 2 0 0 2 2 2 1 RhoGAP domain Phosducin PF02114.16 KFP20582.1 - 0.014 14.3 0.6 0.027 13.4 0.6 1.4 1 0 0 1 1 1 0 Phosducin FTO_CTD PF12934.7 KFP20582.1 - 0.55 10.0 6.9 0.037 13.8 0.9 2.1 3 0 0 3 3 3 0 FTO C-terminal domain SRP14 PF02290.15 KFP20582.1 - 0.98 9.8 5.1 42 4.6 0.3 3.6 3 0 0 3 3 3 0 Signal recognition particle 14kD protein PAPA-1 PF04795.12 KFP20582.1 - 1.2 10.0 13.1 0.081 13.7 5.5 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region Laminin_G_1 PF00054.23 KFP20583.1 - 1.7e-08 34.7 0.0 2.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFP20583.1 - 0.00021 21.9 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_I PF06008.14 KFP20584.1 - 1.1e-46 159.7 17.1 2.8e-46 158.4 17.1 1.6 1 1 0 1 1 1 1 Laminin Domain I TIP120 PF08623.10 KFP20584.1 - 0.09 12.5 3.4 0.066 13.0 0.6 2.0 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) ISG65-75 PF11727.8 KFP20584.1 - 0.13 11.5 7.0 1.6 7.9 1.9 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein CHDCT2 PF08074.11 KFP20584.1 - 0.16 12.1 2.9 0.33 11.1 2.9 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain LPP PF04728.13 KFP20584.1 - 0.17 12.3 0.3 0.17 12.3 0.3 3.6 2 2 2 4 4 4 0 Lipoprotein leucine-zipper DUF948 PF06103.11 KFP20584.1 - 0.18 12.1 7.5 2.8 8.3 0.9 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KFP20584.1 - 0.18 11.3 9.6 0.7 9.4 5.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit HisKA_3 PF07730.13 KFP20584.1 - 0.39 11.3 11.2 6 7.5 1.2 3.7 2 1 1 3 3 3 0 Histidine kinase TPR_MLP1_2 PF07926.12 KFP20584.1 - 0.43 10.6 15.8 0.68 10.0 11.0 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pepsin-I3 PF06394.13 KFP20584.1 - 0.5 10.6 2.9 8.8 6.6 0.1 2.8 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain TMF_TATA_bd PF12325.8 KFP20584.1 - 0.62 10.3 15.7 1.4 9.2 7.5 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Ribosomal_S20p PF01649.18 KFP20584.1 - 0.67 10.6 4.0 6.2 7.5 0.6 2.6 2 1 0 2 2 2 0 Ribosomal protein S20 CENP-O PF09496.10 KFP20584.1 - 0.92 9.5 7.0 0.65 9.9 0.2 2.2 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component DUF883 PF05957.13 KFP20584.1 - 1.1 9.9 17.6 1.3 9.6 0.7 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KFP20584.1 - 1.8 8.7 8.0 14 5.8 1.0 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DegS PF05384.11 KFP20584.1 - 1.8 8.0 13.3 0.079 12.4 1.8 2.9 3 0 0 3 3 3 0 Sensor protein DegS YlqD PF11068.8 KFP20584.1 - 1.9 8.9 10.9 0.86 10.0 1.7 2.9 2 1 1 3 3 3 0 YlqD protein YtxH PF12732.7 KFP20584.1 - 2 9.0 9.3 2.5 8.7 0.7 3.0 2 1 0 2 2 2 0 YtxH-like protein Spore_II_R PF09551.10 KFP20584.1 - 2.6 8.5 6.4 11 6.6 0.2 3.0 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Spc7 PF08317.11 KFP20584.1 - 3.9 6.3 20.1 1.1 8.1 11.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 KFP20584.1 - 5 5.5 8.1 6 5.3 8.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLZ PF16526.5 KFP20584.1 - 5.6 7.4 19.8 0.5 10.8 4.9 3.6 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_N PF00055.17 KFP20586.1 - 2.3e-72 243.4 0.0 2.3e-72 243.4 0.0 2.6 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFP20586.1 - 7.1e-51 170.1 145.0 5.2e-10 39.3 10.1 8.9 9 0 0 9 9 9 8 Laminin EGF domain Laminin_B PF00052.18 KFP20586.1 - 5.7e-34 116.9 0.0 8e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) Aa_trans PF01490.18 KFP20590.1 - 6.6e-73 245.8 28.1 7.6e-73 245.6 28.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATP-synt_J PF04911.12 KFP20590.1 - 0.22 11.2 0.2 1.7 8.3 0.0 2.4 3 0 0 3 3 3 0 ATP synthase j chain SieB PF14163.6 KFP20590.1 - 0.99 8.9 4.7 2.3 7.7 4.7 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B CABIT PF12736.7 KFP20591.1 - 6.2e-105 350.5 4.3 1.1e-52 179.0 0.1 2.1 2 0 0 2 2 2 2 Cell-cycle sustaining, positive selection, DUF1966 PF09260.11 KFP20591.1 - 0.0029 17.9 0.1 0.007 16.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Nop10p PF04135.12 KFP20591.1 - 0.12 12.5 0.1 14 5.8 0.0 2.7 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Leg1 PF05612.12 KFP20592.1 - 4.7e-88 295.5 0.0 5.6e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Leg1 SOGA PF11365.8 KFP20594.1 - 2e-63 211.5 46.8 1.7e-31 109.2 1.0 5.2 4 1 2 6 6 6 3 Protein SOGA DUF2968 PF11180.8 KFP20594.1 - 0.0027 17.4 7.4 0.0027 17.4 7.4 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) TSC22 PF01166.18 KFP20594.1 - 0.0094 16.2 0.3 0.0094 16.2 0.3 7.0 7 1 0 7 7 7 3 TSC-22/dip/bun family Halo_GVPC PF05465.13 KFP20594.1 - 0.036 14.3 0.6 0.092 13.0 0.6 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat SlyX PF04102.12 KFP20594.1 - 0.72 10.5 41.0 1.4 9.6 0.2 7.7 5 3 2 7 7 7 0 SlyX APG6_N PF17675.1 KFP20594.1 - 6.7 7.2 65.1 3.3 8.3 5.7 6.1 4 2 2 6 6 6 0 Apg6 coiled-coil region YabA PF06156.13 KFP20594.1 - 9.6 6.9 48.7 0.89 10.2 3.3 6.9 3 3 4 7 7 7 0 Initiation control protein YabA DUF4482 PF14818.6 KFP20595.1 - 2.3e-34 119.2 16.1 2.3e-34 119.2 16.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4482) Myf5 PF12232.8 KFP20595.1 - 9.3 7.1 8.8 3 8.7 1.4 3.6 3 0 0 3 3 3 0 Myogenic determination factor 5 Homeodomain PF00046.29 KFP20596.1 - 6.9e-22 77.1 8.1 1e-21 76.5 8.1 1.3 1 0 0 1 1 1 1 Homeodomain DUF2209 PF09974.9 KFP20596.1 - 0.054 13.8 0.1 0.074 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeodomain PF00046.29 KFP20597.1 - 4.1e-19 68.2 5.6 4.8e-19 68.0 5.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP20597.1 - 0.00011 22.1 2.4 0.00018 21.3 2.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP20597.1 - 0.0016 18.6 0.1 0.0017 18.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1510) CI-B14_5a PF07347.12 KFP20597.1 - 0.011 15.6 0.2 0.013 15.4 0.2 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) SKICH PF17751.1 KFP20598.1 - 8.3e-34 116.2 2.3 2e-33 115.0 0.7 2.2 2 0 0 2 2 2 1 SKICH domain Zn-C2H2_12 PF18112.1 KFP20598.1 - 2.2e-10 40.8 14.1 1.3e-06 28.7 1.7 2.7 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 KFP20598.1 - 0.00046 20.8 1.7 0.94 10.5 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger ZapB PF06005.12 KFP20598.1 - 0.00086 19.7 60.2 1.2 9.6 14.7 4.9 1 1 3 4 4 4 4 Cell division protein ZapB KASH_CCD PF14662.6 KFP20598.1 - 0.001 18.9 57.4 0.0075 16.1 40.1 3.3 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KFP20598.1 - 0.0078 16.3 1.3 0.0078 16.3 1.3 6.2 4 2 1 6 6 6 1 bZIP transcription factor DUF3450 PF11932.8 KFP20598.1 - 0.011 15.0 11.7 0.011 15.0 11.7 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) GOLGA2L5 PF15070.6 KFP20598.1 - 0.045 12.4 36.3 0.083 11.5 36.3 1.3 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 YabA PF06156.13 KFP20598.1 - 0.048 14.3 42.8 0.28 11.8 2.4 4.7 2 1 2 4 4 4 0 Initiation control protein YabA GAS PF13851.6 KFP20598.1 - 0.059 12.7 53.3 0.58 9.5 20.6 3.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding zf-H2C2_2 PF13465.6 KFP20598.1 - 0.13 12.7 1.6 2.6 8.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain EMP24_GP25L PF01105.24 KFP20598.1 - 0.27 11.1 16.7 47 3.8 13.3 3.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 KFP20598.1 - 0.37 9.6 48.0 0.16 10.8 26.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.6 KFP20598.1 - 0.46 10.2 44.3 0.059 13.1 6.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) UBZ_FAAP20 PF15750.5 KFP20598.1 - 2.2 8.3 8.8 1.5 8.9 1.9 3.1 2 1 1 3 3 2 0 Ubiquitin-binding zinc-finger CENP-F_leu_zip PF10473.9 KFP20598.1 - 2.5 8.1 56.2 0.46 10.5 25.0 3.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 VEK-30 PF12107.8 KFP20598.1 - 3.6 7.6 9.3 12 6.0 0.4 2.8 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway WD40_alt PF14077.6 KFP20598.1 - 6.6 6.7 9.8 1.1 9.1 2.0 3.4 3 1 0 3 3 3 0 Alternative WD40 repeat motif ATP-synt_C PF00137.21 KFP20599.1 - 5.1e-12 45.9 12.4 6.4e-12 45.6 12.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit C UQ_con PF00179.26 KFP20600.1 - 1.2e-29 102.7 0.1 2.6e-29 101.7 0.1 1.6 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFP20600.1 - 0.00024 20.9 1.6 0.0011 18.8 0.0 2.4 2 1 0 3 3 3 1 UEV domain Prok-E2_B PF14461.6 KFP20600.1 - 0.029 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 KFP20600.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 EAP30 PF04157.16 KFP20601.1 - 3.6e-74 249.0 0.1 4.1e-74 248.8 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family L27_2 PF09045.10 KFP20601.1 - 0.028 14.4 1.9 0.071 13.1 0.0 2.4 3 0 0 3 3 3 0 L27_2 ZapD PF07072.11 KFP20601.1 - 0.034 13.9 1.7 9.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Cell division protein Plasmid_RAQPRD PF09686.10 KFP20601.1 - 0.058 13.6 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) EutK_C PF16365.5 KFP20601.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Phage_Mu_Gam PF07352.12 KFP20601.1 - 1.4 8.8 5.3 0.31 10.9 0.9 2.0 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Hormone_2 PF00123.20 KFP20602.1 - 1.2e-11 44.3 4.2 4.4e-09 36.1 0.1 3.3 3 0 0 3 3 3 3 Peptide hormone KH_1 PF00013.29 KFP20603.1 - 2.2e-53 177.9 8.8 2.3e-14 53.0 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFP20603.1 - 7.1e-19 67.4 1.1 0.0054 16.5 0.0 4.5 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFP20603.1 - 3.2e-17 62.2 0.1 0.0043 16.9 0.0 5.0 5 0 0 5 5 5 4 KH domain KH_5 PF13184.6 KFP20603.1 - 3.5e-09 36.6 1.9 0.45 10.6 0.0 4.3 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.22 KFP20603.1 - 3e-08 33.4 0.0 5.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOEP19 PF16005.5 KFP20603.1 - 0.0002 21.3 0.1 1.7 8.7 0.0 4.3 4 0 0 4 4 4 1 KH-like RNA-binding domain CooC_C PF15976.5 KFP20603.1 - 0.061 13.4 0.0 21 5.2 0.0 2.8 2 0 0 2 2 2 0 CS1-pili formation C-terminal RRM_occluded PF16842.5 KFP20603.1 - 0.088 12.7 0.0 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KFP20603.1 - 0.099 12.2 0.2 0.32 10.6 0.1 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 KFP20604.1 - 6.4e-31 105.1 58.4 1.2e-05 25.4 1.5 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP20604.1 - 5.4e-26 89.8 66.6 1.4e-07 31.6 1.3 9.7 9 1 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP20604.1 - 6.7e-23 79.4 58.1 9.5e-05 22.9 0.8 9.4 9 0 0 9 9 9 7 C2H2-type zinc finger zf-met PF12874.7 KFP20604.1 - 3.3e-11 43.2 38.6 0.0019 18.6 0.1 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP20604.1 - 2.6e-09 37.1 38.7 0.046 14.0 0.0 7.5 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFP20604.1 - 0.00066 19.4 27.9 0.11 12.2 0.7 6.8 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP20604.1 - 0.0022 17.9 52.4 0.0094 15.9 0.2 8.7 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP20604.1 - 0.0031 17.4 37.8 0.92 9.5 0.0 8.0 8 0 0 8 8 8 3 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KFP20604.1 - 0.0042 16.6 29.0 3.2 7.4 0.1 8.1 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 KFP20604.1 - 0.0085 16.4 1.3 0.0085 16.4 1.3 5.2 3 3 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 KFP20604.1 - 0.013 15.5 21.7 0.017 15.1 0.5 5.3 4 1 1 5 5 5 0 Adenylate kinase, active site lid BolA PF01722.18 KFP20604.1 - 0.02 15.2 6.2 0.71 10.2 0.6 3.8 2 2 1 3 3 3 0 BolA-like protein SDA1 PF05285.12 KFP20604.1 - 0.026 14.0 22.1 0.038 13.4 22.1 1.2 1 0 0 1 1 1 0 SDA1 zf-C2H2_2 PF12756.7 KFP20604.1 - 0.029 14.7 46.2 0.5 10.7 1.8 6.1 1 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) zf_C2H2_13 PF18508.1 KFP20604.1 - 0.23 11.1 6.2 6.3 6.5 0.1 4.6 4 0 0 4 4 4 0 Zinc finger domain zf-C2H2_3rep PF18868.1 KFP20604.1 - 0.41 11.3 0.1 0.41 11.3 0.1 7.3 2 1 6 8 8 8 0 Zinc finger C2H2-type, 3 repeats DUF2502 PF10697.9 KFP20604.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2502) Zn-ribbon_8 PF09723.10 KFP20604.1 - 1.7 8.8 37.7 0.88 9.7 1.3 6.5 4 3 3 7 7 7 0 Zinc ribbon domain BUD22 PF09073.10 KFP20604.1 - 3.2 7.0 27.4 4.7 6.5 27.4 1.1 1 0 0 1 1 1 0 BUD22 HNH_5 PF14279.6 KFP20604.1 - 8.6 6.3 25.1 2.7 7.9 0.4 6.7 5 3 1 6 6 6 0 HNH endonuclease Neurexophilin PF06312.12 KFP20605.1 - 2.1e-103 344.3 1.9 2.3e-103 344.2 1.9 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.19 KFP20605.1 - 0.01 16.7 0.5 0.91 10.4 0.0 2.2 1 1 1 2 2 2 0 Filamin/ABP280 repeat UAA PF08449.11 KFP20606.1 - 2e-50 171.7 6.9 2.6e-50 171.3 6.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFP20606.1 - 7.6e-14 52.0 18.6 2.7e-08 34.1 12.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KFP20606.1 - 1.9e-13 50.4 4.8 9.2e-08 31.8 1.3 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KFP20606.1 - 9.9e-05 21.4 4.3 0.0058 15.6 0.0 2.1 1 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KFP20606.1 - 0.0076 15.5 1.7 0.39 9.8 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter FAM117 PF15388.6 KFP20607.1 - 2.4e-118 395.2 3.1 3e-118 394.8 3.1 1.1 1 0 0 1 1 1 1 Protein Family FAM117 MOZ_SAS PF01853.18 KFP20608.1 - 2.7e-86 287.8 1.4 4.3e-86 287.1 1.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFP20608.1 - 2.1e-23 81.6 1.6 2.1e-23 81.6 1.6 2.4 3 0 0 3 3 3 1 MYST family zinc finger domain zf-C2HC PF01530.18 KFP20608.1 - 2.7e-06 27.5 3.2 2.8e-06 27.4 1.3 2.0 2 0 0 2 2 2 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 KFP20608.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 KFP20608.1 - 0.031 14.7 0.4 0.081 13.3 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type 7tm_4 PF13853.6 KFP20609.1 - 4.4e-46 157.9 11.8 5.2e-46 157.6 11.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20609.1 - 1.7e-30 106.3 15.8 3.1e-30 105.4 15.8 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP20609.1 - 0.0078 15.6 10.9 0.017 14.5 10.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP20610.1 - 2.8e-23 83.1 2.9 3.1e-23 82.9 2.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20610.1 - 2.8e-05 23.6 8.3 4e-05 23.1 8.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sushi PF00084.20 KFP20611.1 - 1.1e-41 141.2 32.8 1.4e-09 38.4 1.2 6.4 6 1 0 6 6 6 6 Sushi repeat (SCR repeat) Sushi PF00084.20 KFP20612.1 - 2.7e-14 53.5 1.0 1.1e-11 45.2 0.2 2.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Sushi PF00084.20 KFP20613.1 - 3.2e-27 94.9 7.9 2.7e-12 47.1 0.2 3.0 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) HRM PF02793.22 KFP20613.1 - 0.0074 16.6 0.5 0.74 10.2 0.1 2.4 2 0 0 2 2 2 2 Hormone receptor domain Calreticulin PF00262.18 KFP20614.1 - 1.7e-163 543.7 15.9 1.9e-163 543.6 15.9 1.0 1 0 0 1 1 1 1 Calreticulin family Glyco_transf_54 PF04666.13 KFP20615.1 - 7.6e-122 405.7 0.3 9e-122 405.5 0.3 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Cnd1 PF12717.7 KFP20616.1 - 0.0019 18.3 0.1 0.19 11.7 0.0 3.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KFP20616.1 - 0.0073 15.5 0.4 0.018 14.2 0.4 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain FUSC-like PF12805.7 KFP20616.1 - 0.028 13.5 0.4 0.8 8.7 0.0 3.0 2 1 1 3 3 3 0 FUSC-like inner membrane protein yccS Mlh1_C PF16413.5 KFP20616.1 - 0.084 12.2 1.5 0.12 11.7 0.4 1.8 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus Carboxyl_trans PF01039.22 KFP20617.1 - 1.2e-189 631.1 0.0 1.3e-189 630.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KFP20617.1 - 0.059 12.8 1.4 0.64 9.5 0.0 2.6 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) MSL2-CXC PF16682.5 KFP20618.1 - 2.9e-19 68.9 20.3 5.5e-19 68.0 20.3 1.5 1 0 0 1 1 1 1 CXC domain of E3 ubiquitin-protein ligase MSL2 EF-hand_13 PF17958.1 KFP20619.1 - 4.5e-40 135.4 0.1 7.3e-39 131.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KFP20619.1 - 6.4e-21 74.6 5.4 4e-20 72.1 0.6 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KFP20619.1 - 1.8e-05 24.0 0.0 0.0008 18.8 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KFP20619.1 - 9.1e-05 22.1 0.3 0.036 14.0 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KFP20619.1 - 0.00028 20.7 0.1 1 9.2 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP20619.1 - 0.00038 19.8 0.2 0.065 12.8 0.1 3.8 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 KFP20619.1 - 0.022 15.1 1.4 5.8 7.3 0.3 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DBR1 PF05011.13 KFP20620.1 - 1.3e-35 122.9 0.1 2.3e-35 122.0 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Arm PF00514.23 KFP20621.1 - 6.8e-18 64.1 22.6 0.00019 21.4 0.2 11.3 12 0 0 12 12 12 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP20621.1 - 1.4e-08 35.0 3.9 0.0096 16.4 0.1 6.4 7 1 1 8 8 8 2 HEAT-like repeat V-ATPase_H_C PF11698.8 KFP20621.1 - 5.8e-07 29.6 9.7 0.17 12.0 0.0 5.8 4 2 2 6 6 6 3 V-ATPase subunit H HEAT PF02985.22 KFP20621.1 - 6e-07 29.2 17.7 0.032 14.5 0.1 8.2 9 0 0 9 9 9 2 HEAT repeat Uso1_p115_head PF04869.14 KFP20621.1 - 0.0011 18.2 2.7 1.1 8.4 0.1 3.8 3 1 1 4 4 4 1 Uso1 / p115 like vesicle tethering protein, head region Cnd1 PF12717.7 KFP20621.1 - 0.065 13.3 15.7 0.46 10.5 0.9 4.4 2 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 KFP20621.1 - 0.18 12.2 4.2 13 6.3 0.1 4.3 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 KFP20621.1 - 0.68 10.0 6.8 0.82 9.8 0.3 3.5 3 1 0 4 4 4 0 Parkin co-regulated protein DUF3361 PF11841.8 KFP20621.1 - 2.4 8.1 18.0 4.8 7.1 2.4 4.5 2 1 1 4 4 4 0 Domain of unknown function (DUF3361) RTTN_N PF14726.6 KFP20621.1 - 2.8 8.8 8.5 73 4.3 0.0 4.8 2 1 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning Thioredoxin PF00085.20 KFP20622.1 - 1e-06 28.7 0.0 1.1e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Vps8 PF12816.7 KFP20623.1 - 6.6e-60 202.0 9.6 2.7e-58 196.8 1.2 3.3 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFP20623.1 - 4e-08 33.2 8.4 3.8e-05 23.6 1.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_11 PF17123.5 KFP20623.1 - 2.6e-05 23.8 5.0 9.5e-05 22.1 5.0 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP20623.1 - 0.0069 16.4 5.8 0.024 14.7 5.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP20623.1 - 0.014 15.7 8.4 0.044 14.1 8.4 1.9 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 KFP20623.1 - 0.22 11.5 9.0 0.45 10.5 9.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 KFP20623.1 - 3.5 7.6 9.1 11 6.0 9.1 2.0 1 0 0 1 1 1 0 zinc-RING finger domain UPF0524 PF15823.5 KFP20624.1 - 7.3e-85 284.2 4.6 8.2e-85 284.0 4.6 1.0 1 0 0 1 1 1 1 UPF0524 of C3orf70 3HCDH_N PF02737.18 KFP20625.1 - 8.9e-52 175.6 0.4 1.2e-51 175.2 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFP20625.1 - 1.4e-28 99.3 0.0 5.3e-25 87.9 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFP20625.1 - 0.0022 18.2 0.1 0.0058 16.8 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KFP20625.1 - 0.0074 16.5 0.1 0.022 15.0 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 KFP20625.1 - 0.052 14.1 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ECH_1 PF00378.20 KFP20626.1 - 5.5e-35 120.9 0.1 6.1e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP20626.1 - 3e-27 96.0 0.1 4e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFP20626.1 - 8e-05 22.6 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S49 SeleniumBinding PF11524.8 KFP20626.1 - 0.031 14.7 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Selenium binding protein Pkinase_Tyr PF07714.17 KFP20627.1 - 2.8e-64 216.9 0.0 4.3e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP20627.1 - 2.6e-59 200.8 0.0 4.8e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFP20627.1 - 0.0012 17.7 0.4 0.0029 16.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF737 PF05300.11 KFP20627.1 - 0.023 15.1 0.4 0.023 15.1 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF737) APH PF01636.23 KFP20627.1 - 0.073 13.0 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family SNARE_assoc PF09335.11 KFP20629.1 - 1.6e-17 64.1 5.3 1.6e-17 64.1 5.3 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Lipase PF00151.19 KFP20630.1 - 1.4e-83 281.1 0.0 1.9e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Apc13p PF05839.11 KFP20631.1 - 3.6e-20 71.9 0.3 5e-20 71.5 0.3 1.2 1 0 0 1 1 1 1 Apc13p protein CEP63 PF17045.5 KFP20632.1 - 2e-107 359.1 57.6 2e-107 359.1 57.6 4.7 3 1 2 5 5 5 3 Centrosomal protein of 63 kDa Transglut_core PF01841.19 KFP20633.1 - 5.3e-15 55.8 0.0 1e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KFP20633.1 - 0.085 12.4 0.1 0.3 10.6 0.1 1.9 1 1 0 1 1 1 0 Transglutaminase-like domain Pkinase_Tyr PF07714.17 KFP20634.1 - 2.9e-100 334.8 0.0 3.4e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP20634.1 - 1.2e-50 172.3 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP20634.1 - 1.3e-13 51.6 1.0 2.4e-13 50.8 1.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP20634.1 - 0.0044 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain ABC1 PF03109.16 KFP20634.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 KFP20634.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP20634.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Gb3_synth PF04572.12 KFP20635.1 - 9.2e-44 148.8 0.7 1.4e-43 148.1 0.7 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 KFP20635.1 - 5.6e-19 68.6 0.0 1.4e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dzip-like_N PF13815.6 KFP20636.1 - 3.1e-30 104.5 0.1 3.1e-30 104.5 0.1 2.9 2 1 0 2 2 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Caldesmon PF02029.15 KFP20636.1 - 0.0011 17.8 14.1 0.0012 17.7 14.1 1.1 1 0 0 1 1 1 1 Caldesmon EMP24_GP25L PF01105.24 KFP20636.1 - 0.0051 16.8 2.9 0.0095 15.9 2.9 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Prominin PF05478.11 KFP20636.1 - 0.023 12.7 4.0 0.038 11.9 4.0 1.3 1 0 0 1 1 1 0 Prominin Herpes_UL6 PF01763.16 KFP20636.1 - 0.024 13.2 3.8 0.028 12.9 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like BBP1_C PF15272.6 KFP20636.1 - 0.028 14.3 9.7 0.043 13.6 9.7 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal FapA PF03961.13 KFP20636.1 - 0.032 12.9 4.5 0.034 12.8 4.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A WDCP PF15390.6 KFP20636.1 - 0.035 12.5 3.5 0.04 12.3 3.5 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4407 PF14362.6 KFP20636.1 - 0.058 12.7 9.9 0.07 12.5 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PA26 PF04636.13 KFP20636.1 - 0.33 9.8 5.5 0.38 9.6 5.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CCDC92 PF14916.6 KFP20636.1 - 0.34 10.7 10.1 2.9 7.7 1.7 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function V_ATPase_I PF01496.19 KFP20636.1 - 1.4 6.8 5.2 1.5 6.6 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 KFP20636.1 - 1.5 8.9 7.3 3.1 7.8 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) SAB PF04382.13 KFP20636.1 - 1.9 8.6 7.8 13 6.0 2.6 2.4 2 0 0 2 2 2 0 SAB domain DUF3037 PF11236.8 KFP20636.1 - 1.9 8.9 12.0 6.6 7.2 3.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) DUF5345 PF17280.2 KFP20636.1 - 2.4 8.2 8.6 6.7 6.8 8.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) YabA PF06156.13 KFP20636.1 - 2.8 8.6 10.8 8.2 7.1 10.8 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Allexi_40kDa PF05549.11 KFP20636.1 - 2.9 7.3 5.4 1.5 8.3 2.8 1.7 1 1 0 2 2 2 0 Allexivirus 40kDa protein Rho_Binding PF08912.11 KFP20636.1 - 3.1 8.7 22.5 0.095 13.5 13.4 2.7 2 1 1 3 3 3 0 Rho Binding Vfa1 PF08432.10 KFP20636.1 - 3.9 7.8 13.6 4 7.7 9.8 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PMP22_Claudin PF00822.20 KFP20637.1 - 6e-31 107.5 14.3 8e-31 107.1 14.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP20637.1 - 3.1e-12 46.6 15.6 6.4e-11 42.4 15.6 2.1 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.10 KFP20637.1 - 0.0046 16.8 1.8 0.11 12.3 1.7 2.4 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.11 KFP20637.1 - 0.22 11.4 11.2 0.16 11.8 9.4 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein Phage_holin_3_6 PF07332.11 KFP20637.1 - 2.6 8.1 21.3 0.12 12.4 6.0 2.5 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF308 PF03729.13 KFP20637.1 - 5.2 7.5 24.3 0.21 11.9 8.5 3.0 2 1 2 4 4 4 0 Short repeat of unknown function (DUF308) HMG_box PF00505.19 KFP20638.1 - 1.3e-27 96.0 5.0 1.3e-27 96.0 5.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP20638.1 - 4.7e-12 46.3 4.1 7.9e-12 45.6 4.1 1.4 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.8 KFP20638.1 - 3.2e-07 31.3 1.2 4.5e-06 27.6 1.2 2.4 1 1 0 1 1 1 1 SOX transcription factor TBCC PF07986.12 KFP20639.1 - 1.3e-37 128.2 0.4 2.5e-37 127.2 0.4 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KFP20639.1 - 7.9e-06 25.6 1.7 1.6e-05 24.6 1.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal MHC_I_3 PF16497.5 KFP20640.1 - 8.1e-08 32.0 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 MHC-I family domain MHC_I PF00129.18 KFP20640.1 - 2.1e-05 24.1 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 PFK PF00365.20 KFP20641.1 - 4.9e-197 652.8 5.0 4.1e-101 338.1 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase LRR_4 PF12799.7 KFP20642.1 - 1e-08 35.3 13.2 3.7e-05 24.0 3.4 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP20642.1 - 3.8e-07 29.8 0.3 9.9e-07 28.4 0.3 1.6 1 1 0 1 1 1 1 Leucine-rich repeat SART-1 PF03343.13 KFP20642.1 - 1.4e-05 23.9 0.2 1.9e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 SART-1 family LRR_8 PF13855.6 KFP20642.1 - 8.8e-05 22.2 3.7 0.004 16.9 3.3 2.9 1 1 1 2 2 2 2 Leucine rich repeat Arg_repressor PF01316.21 KFP20642.1 - 0.016 15.0 0.4 0.069 12.9 0.1 2.3 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain RRM_1 PF00076.22 KFP20643.1 - 4.4e-22 77.7 0.0 6.1e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP20643.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KFP20643.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Apt1 PF10351.9 KFP20643.1 - 0.1 11.5 13.0 0.11 11.3 13.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 KFP20643.1 - 0.26 10.1 5.3 0.26 10.0 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KFP20643.1 - 0.53 9.0 4.6 0.55 8.9 4.6 1.1 1 0 0 1 1 1 0 Presenilin KH_1 PF00013.29 KFP20644.1 - 4.7e-57 189.7 12.9 6.8e-16 57.9 0.2 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 KFP20644.1 - 3.2e-17 62.1 6.8 0.00042 20.1 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 KFP20644.1 - 1.2e-15 57.1 3.2 0.0012 18.6 0.1 5.0 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 KFP20644.1 - 3.3e-07 30.0 0.0 7.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.6 KFP20644.1 - 4.2e-07 29.9 4.0 0.4 10.8 0.1 4.5 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 KFP20644.1 - 8.7e-06 25.7 0.1 0.13 12.3 0.0 3.9 4 0 0 4 4 4 1 KH-like RNA-binding domain RRM_3 PF08777.11 KFP20644.1 - 0.027 14.5 0.4 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 KFP20644.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLS PF14611.6 KFP20644.1 - 0.19 11.6 3.9 2.3 8.0 0.2 3.5 3 1 1 4 4 4 0 Mitochondrial inner-membrane-bound regulator Angiomotin_C PF12240.8 KFP20645.1 - 1e-69 234.2 0.3 1e-69 234.2 0.3 4.3 2 1 2 4 4 4 1 Angiomotin C terminal DUF4288 PF14119.6 KFP20645.1 - 0.21 12.0 3.8 0.92 9.9 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF4407 PF14362.6 KFP20645.1 - 0.62 9.4 27.4 0.0084 15.5 9.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Pkinase_Tyr PF07714.17 KFP20646.1 - 6.6e-50 169.8 0.1 1e-49 169.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP20646.1 - 8.2e-17 61.4 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WIF PF02019.18 KFP20646.1 - 3.9e-09 36.3 2.0 3.9e-09 36.3 0.5 1.8 2 0 0 2 2 2 1 WIF domain SID-1_RNA_chan PF13965.6 KFP20646.1 - 0.038 12.4 0.7 0.054 11.9 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Transferrin PF00405.17 KFP20647.1 - 5.5e-208 689.7 6.0 2.3e-84 283.4 3.6 3.2 3 0 0 3 3 3 3 Transferrin SRPRB PF09439.10 KFP20647.1 - 1.8e-58 197.0 0.1 1.8e-58 197.0 0.1 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KFP20647.1 - 6.9e-10 38.6 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Phosphonate-bd PF12974.7 KFP20647.1 - 4.4e-09 36.3 0.0 0.00026 20.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein GTP_EFTU PF00009.27 KFP20647.1 - 4.5e-05 23.1 0.0 8.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP20647.1 - 0.00075 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3584 PF12128.8 KFP20647.1 - 0.018 12.6 0.1 0.027 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FeoB_N PF02421.18 KFP20647.1 - 0.084 12.4 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Gal-3-0_sulfotr PF06990.11 KFP20648.1 - 6.2e-123 410.6 0.5 6.9e-123 410.5 0.5 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 KFP20648.1 - 0.00013 21.9 0.1 0.0014 18.6 0.1 2.4 1 1 0 1 1 1 1 Sulfotransferase family SgrT PF15894.5 KFP20648.1 - 0.089 12.8 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT MIP PF00230.20 KFP20649.1 - 7.7e-09 35.6 5.7 1.1e-08 35.1 5.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 KFP20650.1 - 5.9e-74 248.8 0.0 8.3e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20650.1 - 1.5e-47 162.1 0.0 2.6e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP20650.1 - 3.8e-25 88.0 0.0 9e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP20650.1 - 3.5e-08 33.1 0.1 0.00036 20.0 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFP20650.1 - 3.3e-06 26.1 0.0 6.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP20650.1 - 0.0036 17.3 0.0 0.046 13.6 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP20650.1 - 0.0045 16.0 1.0 0.027 13.4 1.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP20650.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIG-X PF08320.12 KFP20651.1 - 5.3e-42 144.1 0.0 6.1e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 CEP19 PF14933.6 KFP20652.1 - 6.9e-37 127.3 2.7 7.6e-37 127.2 2.7 1.0 1 0 0 1 1 1 1 CEP19-like protein LRR_8 PF13855.6 KFP20653.1 - 7.8e-52 172.9 61.0 1.9e-10 40.4 2.4 9.6 8 2 2 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFP20653.1 - 8e-30 102.4 55.8 0.00071 19.9 0.8 12.3 5 4 5 13 13 13 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP20653.1 - 1.3e-12 46.4 47.7 0.27 11.9 0.1 17.1 17 1 0 17 17 17 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP20653.1 - 7.2e-05 22.5 48.5 5 7.4 0.1 14.5 15 0 0 15 15 15 4 Leucine Rich repeat LRR_9 PF14580.6 KFP20653.1 - 0.00027 20.5 16.3 0.055 13.0 0.1 5.2 2 1 4 6 6 6 3 Leucine-rich repeat LRR_5 PF13306.6 KFP20653.1 - 0.0018 18.3 0.0 1.1 9.2 0.0 4.2 5 0 0 5 5 5 1 BspA type Leucine rich repeat region (6 copies) TauD PF02668.16 KFP20653.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.32 KFP20654.1 - 3e-16 59.5 0.4 0.0002 22.1 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP20654.1 - 1.4e-06 28.5 0.0 0.0025 18.1 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_4 PF14447.6 KFP20655.1 - 2.5e-07 30.4 10.1 7.1e-07 29.0 10.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFP20655.1 - 7.9e-07 28.8 14.1 1.7e-06 27.8 14.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP20655.1 - 8.9e-07 28.7 14.3 2.3e-06 27.4 14.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP20655.1 - 2.4e-06 27.3 13.4 4.6e-06 26.4 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP20655.1 - 2.3e-05 24.3 10.5 6.5e-05 22.9 10.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP20655.1 - 2.8e-05 24.0 11.9 6.5e-05 22.8 11.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP20655.1 - 0.00024 21.2 15.5 0.00024 21.2 15.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFP20655.1 - 0.0015 18.8 16.4 0.0036 17.6 16.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 KFP20655.1 - 0.19 11.9 8.1 0.42 10.8 8.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KFP20655.1 - 2 8.3 13.9 3.4 7.5 12.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain UBX PF00789.20 KFP20656.1 - 6e-20 71.2 0.0 1.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KFP20656.1 - 2.2e-15 56.6 0.1 4e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KFP20656.1 - 3.5e-09 36.3 0.1 1e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 KFP20656.1 - 0.023 14.6 3.6 0.078 12.9 3.6 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredox_DsbH PF03190.15 KFP20656.1 - 0.035 14.1 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KFP20656.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain L6_membrane PF05805.12 KFP20657.1 - 1e-63 214.4 11.3 1.1e-63 214.2 11.3 1.0 1 0 0 1 1 1 1 L6 membrane protein ATP19 PF11022.8 KFP20657.1 - 0.18 12.2 0.1 0.51 10.8 0.1 1.7 1 0 0 1 1 1 0 ATP synthase subunit K BNR_2 PF13088.6 KFP20658.1 - 1e-31 110.3 0.0 1.5e-27 96.6 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.6 KFP20658.1 - 5.6e-05 22.6 0.0 6.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFP20658.1 - 0.0018 18.0 2.0 4.6 7.7 0.0 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat ING PF12998.7 KFP20659.1 - 1.9e-28 99.0 2.7 2.7e-28 98.5 2.7 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFP20659.1 - 2e-06 27.6 8.1 4.3e-06 26.5 8.1 1.6 1 0 0 1 1 1 1 PHD-finger RRF PF01765.19 KFP20659.1 - 0.0072 16.3 1.9 0.01 15.8 1.9 1.2 1 0 0 1 1 1 1 Ribosome recycling factor zf-HC5HC2H PF13771.6 KFP20659.1 - 0.016 15.5 1.1 0.03 14.6 0.4 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Spc7 PF08317.11 KFP20659.1 - 0.022 13.7 3.4 0.027 13.4 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HD_3 PF13023.6 KFP20659.1 - 0.068 13.1 1.0 0.1 12.5 1.0 1.2 1 0 0 1 1 1 0 HD domain Spectrin_like PF18373.1 KFP20659.1 - 0.069 13.2 0.2 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 Spectrin like domain DUF4407 PF14362.6 KFP20659.1 - 2.1 7.6 4.5 1 8.7 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Thymidylate_kin PF02223.17 KFP20660.1 - 5.8e-39 133.7 0.0 7.5e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase Peptidase_C54 PF03416.19 KFP20661.1 - 1.9e-103 345.7 0.0 2.3e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DUF1794 PF08768.11 KFP20662.1 - 1.1e-40 139.0 0.0 1.8e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) THAP PF05485.12 KFP20662.1 - 6.9e-12 46.1 0.6 6.9e-12 46.1 0.6 2.1 2 0 0 2 2 2 1 THAP domain HrpB7 PF09486.10 KFP20662.1 - 0.0036 17.7 0.2 0.0076 16.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 KFP20662.1 - 0.0042 16.9 0.4 0.0077 16.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) NPC1_N PF16414.5 KFP20662.1 - 0.026 14.1 0.8 0.053 13.1 0.8 1.5 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus DHR10 PF18595.1 KFP20662.1 - 0.041 14.0 0.5 0.087 12.9 0.5 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Csm1_N PF18504.1 KFP20662.1 - 0.33 11.3 2.2 1.3 9.5 2.2 1.9 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 KFP20662.1 - 0.99 9.2 2.5 0.62 9.9 0.3 1.7 2 0 0 2 2 2 0 Septum formation initiator LSDAT_euk PF18139.1 KFP20663.1 - 8.1e-80 268.0 0.1 1.4e-79 267.2 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KFP20663.1 - 2.6e-24 85.6 0.2 4.4e-24 84.8 0.2 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KFP20663.1 - 2.2e-20 73.0 17.4 3.7e-20 72.2 17.4 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFP20663.1 - 0.037 12.7 9.4 0.029 13.0 4.5 2.3 1 1 0 2 2 2 0 Polycystin cation channel LDcluster4 PF18306.1 KFP20663.1 - 0.076 12.6 1.7 6.4 6.3 0.2 2.3 2 0 0 2 2 2 0 SLOG cluster4 family EPTP PF03736.17 KFP20664.1 - 3.9e-92 302.0 25.8 9e-21 73.6 0.7 7.8 7 1 0 7 7 7 7 EPTP domain UQ_con PF00179.26 KFP20665.1 - 2.7e-47 159.9 0.0 3e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bcl-2 PF00452.19 KFP20666.1 - 8.6e-23 80.9 0.1 1.7e-22 80.0 0.1 1.5 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Pkinase PF00069.25 KFP20667.1 - 6.7e-56 189.6 0.0 5.4e-45 153.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20667.1 - 3.2e-39 134.8 0.0 6.8e-33 114.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP20667.1 - 2e-05 23.6 0.0 3.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 KFP20667.1 - 6.7e-05 22.6 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KFP20667.1 - 0.0032 16.8 0.1 0.02 14.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFP20667.1 - 0.025 13.5 0.0 3 6.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Septin PF00735.18 KFP20668.1 - 1.9e-129 430.9 0.1 2.3e-129 430.7 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP20668.1 - 2.6e-08 33.9 0.1 9.6e-08 32.1 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP20668.1 - 3.5e-06 26.7 0.2 0.0036 16.9 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP20668.1 - 5.7e-06 26.3 1.5 0.0012 18.8 0.4 2.6 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KFP20668.1 - 0.00014 21.3 0.2 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 KFP20668.1 - 0.00053 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KFP20668.1 - 0.00073 19.6 1.5 0.075 13.1 0.0 2.9 3 1 1 4 4 4 1 Dynamin family AAA_22 PF13401.6 KFP20668.1 - 0.0028 17.9 0.2 0.016 15.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 KFP20668.1 - 0.004 17.4 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP20668.1 - 0.0053 17.2 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KFP20668.1 - 0.009 16.5 0.1 0.022 15.3 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KFP20668.1 - 0.011 15.1 0.3 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KFP20668.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFP20668.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IIGP PF05049.13 KFP20668.1 - 0.095 11.7 0.3 0.48 9.4 0.0 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) KH_1 PF00013.29 KFP20669.1 - 1.2e-194 630.5 59.2 3.6e-16 58.7 0.6 15.7 15 1 0 15 15 15 15 KH domain SLS PF14611.6 KFP20669.1 - 1.3e-19 70.9 22.4 5.9e-05 23.0 0.4 9.3 2 2 8 11 11 11 7 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KFP20669.1 - 3.5e-17 62.0 47.0 0.013 15.4 1.8 12.4 11 2 1 13 13 13 8 KH domain KH_5 PF13184.6 KFP20669.1 - 9.9e-08 32.0 29.9 1.6 8.9 0.3 11.3 11 1 1 12 12 12 4 NusA-like KH domain DUF4530 PF15039.6 KFP20669.1 - 0.0025 17.9 0.1 2.4 8.4 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4530) BMC PF00936.19 KFP20669.1 - 0.0061 16.5 5.4 55 3.8 0.1 7.5 10 0 0 10 10 10 0 BMC domain Lactamase_B_4 PF13691.6 KFP20669.1 - 0.015 14.9 0.0 21 4.9 0.0 4.0 3 0 0 3 3 3 0 tRNase Z endonuclease DUF2096 PF09869.9 KFP20669.1 - 0.022 14.8 18.5 2.5 8.1 0.4 7.4 8 1 0 9 9 9 0 Uncharacterized protein conserved in archaea (DUF2096) DUF1471 PF07338.13 KFP20669.1 - 0.077 13.0 0.1 4.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) DUF531 PF04407.12 KFP20669.1 - 1.4 9.0 6.0 22 5.1 0.0 4.9 3 2 2 5 5 5 0 Protein of unknown function (DUF531) KH_4 PF13083.6 KFP20669.1 - 2.6 8.0 28.6 2 8.4 0.1 10.0 9 2 3 12 12 12 0 KH domain FtsQ PF03799.15 KFP20669.1 - 3.3 8.6 5.0 3.9e+02 1.9 0.0 5.6 3 2 3 6 6 6 0 Cell division protein FtsQ LRR_4 PF12799.7 KFP20670.1 - 2.5e-37 126.2 42.7 1.4e-09 38.0 2.6 7.2 1 1 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP20670.1 - 1.7e-23 82.1 39.4 8.6e-08 31.8 7.9 6.3 2 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KFP20670.1 - 2.6e-23 82.4 34.7 1.5e-08 34.3 8.0 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KFP20670.1 - 0.00039 20.2 24.0 2.7 8.3 0.0 8.1 8 1 1 9 9 9 3 Leucine Rich repeat Ribosomal_L50 PF10501.9 KFP20670.1 - 0.017 15.3 3.8 8.5 6.6 0.1 3.6 1 1 2 4 4 4 0 Ribosomal subunit 39S LRR_1 PF00560.33 KFP20670.1 - 0.052 14.1 33.5 1.7 9.5 0.4 9.2 8 1 0 8 8 8 0 Leucine Rich Repeat UB2H PF14814.6 KFP20670.1 - 0.13 12.3 8.9 31 4.7 0.0 5.6 2 2 4 7 7 7 0 Bifunctional transglycosylase second domain RNA_pol_Rpb1_5 PF04998.17 KFP20670.1 - 3.5 7.0 4.8 8.6 5.7 4.7 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PP2C PF00481.21 KFP20671.1 - 1.3e-62 211.8 0.2 1.6e-62 211.5 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KFP20671.1 - 6.3e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C C1q PF00386.21 KFP20672.1 - 0.0017 18.6 0.1 0.005 17.1 0.1 1.8 1 1 0 1 1 1 1 C1q domain TNF PF00229.18 KFP20672.1 - 0.049 13.6 0.2 0.074 13.0 0.2 1.3 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family BACK PF07707.15 KFP20673.1 - 2.2e-29 101.6 0.6 4.7e-29 100.5 0.2 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KFP20673.1 - 1.5e-28 99.3 0.0 2.5e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 KFP20673.1 - 1.7e-23 81.9 24.4 1.2e-08 34.4 0.2 8.5 7 2 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 KFP20673.1 - 1.3e-20 72.9 8.8 6e-06 26.4 0.3 6.9 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFP20673.1 - 1.7e-14 53.1 3.3 0.31 11.1 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 KFP20673.1 - 6.5e-09 35.9 3.4 0.0005 20.3 0.7 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP20673.1 - 2.1e-08 34.1 8.9 0.043 13.8 0.6 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP20673.1 - 5.2e-07 29.5 0.0 0.012 15.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif zf_CCCH_5 PF18384.1 KFP20674.1 - 3.6e-20 71.8 14.6 3.6e-20 71.8 14.6 2.9 2 1 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 KFP20674.1 - 8.7e-07 28.7 7.7 7.7e-06 25.7 2.2 6.5 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP20674.1 - 0.0014 18.6 26.0 0.048 13.7 0.0 5.8 5 0 0 5 5 5 2 Zinc finger domain Filament PF00038.21 KFP20674.1 - 0.0017 18.0 7.0 0.0025 17.5 7.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 KFP20674.1 - 0.026 14.0 4.8 0.042 13.3 4.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 MLIP PF15274.6 KFP20674.1 - 0.043 13.7 0.6 0.34 10.8 0.3 2.2 2 0 0 2 2 2 0 Muscular LMNA-interacting protein Exonuc_VII_L PF02601.15 KFP20674.1 - 0.077 12.6 0.6 0.11 12.1 0.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF932 PF06067.11 KFP20674.1 - 0.11 12.2 3.0 0.17 11.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Rep_4 PF05797.11 KFP20674.1 - 0.19 10.8 2.4 0.3 10.1 2.4 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Torus PF16131.5 KFP20674.1 - 0.21 12.3 0.1 0.21 12.3 0.1 5.4 4 2 2 6 6 6 0 Torus domain MAD PF05557.13 KFP20674.1 - 0.22 9.9 9.1 0.3 9.4 9.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FapA PF03961.13 KFP20674.1 - 0.3 9.6 2.4 0.44 9.1 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3560 PF12083.8 KFP20674.1 - 0.58 10.3 6.7 1.2 9.3 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) PCRF PF03462.18 KFP20674.1 - 0.77 9.6 5.0 1.3 8.9 5.0 1.3 1 0 0 1 1 1 0 PCRF domain Occludin_ELL PF07303.13 KFP20674.1 - 1.6 9.5 5.1 3.4 8.4 5.1 1.5 1 0 0 1 1 1 0 Occludin homology domain DUF3450 PF11932.8 KFP20674.1 - 2.7 7.2 9.9 4.3 6.6 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Alanine_zipper PF11839.8 KFP20674.1 - 5.3 7.5 12.4 8.6 6.8 12.4 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Mito_fiss_reg PF05308.11 KFP20674.1 - 6.5 6.8 20.5 0.023 14.8 8.8 2.4 1 1 1 2 2 1 0 Mitochondrial fission regulator Borrelia_P83 PF05262.11 KFP20674.1 - 9.7 4.5 11.4 15 4.0 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PRKCSH_1 PF13015.6 KFP20675.1 - 5.4e-09 35.9 0.2 4.9e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFP20675.1 - 1.5e-07 32.3 6.0 2.6e-07 31.5 3.2 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein LRRFIP PF09738.9 KFP20675.1 - 0.0073 15.8 2.9 0.01 15.3 2.9 1.2 1 0 0 1 1 1 1 LRRFIP family Syntaxin-18_N PF10496.9 KFP20675.1 - 0.0091 16.2 1.8 0.016 15.4 1.8 1.3 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus VP_N-CPKC PF11475.8 KFP20675.1 - 0.074 13.0 2.7 1.2 9.1 0.4 2.9 2 1 0 2 2 2 0 Virion protein N terminal domain LIG3_BRCT PF16759.5 KFP20675.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Ribosomal_L30_N PF08079.12 KFP20675.1 - 0.2 11.9 3.3 0.39 11.0 3.3 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Ribo_biogen_C PF04034.13 KFP20676.1 - 1e-47 161.0 0.0 1.3e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal UQ_con PF00179.26 KFP20677.1 - 2.1e-49 166.8 0.0 2.4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP20677.1 - 4.3e-05 23.2 0.0 4.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B BTB_2 PF02214.22 KFP20678.1 - 3.7e-11 43.2 0.0 6.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KFP20678.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-RING_9 PF13901.6 KFP20678.1 - 0.062 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SAM_LFY PF01698.16 KFP20678.1 - 0.094 12.7 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Floricaula / Leafy protein SAM domain Pkinase PF00069.25 KFP20679.1 - 1.3e-66 224.7 0.0 1.5e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20679.1 - 1.9e-34 119.1 0.0 2.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 KFP20679.1 - 6e-29 100.2 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KFP20679.1 - 9.9e-07 28.3 0.0 1.8e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP20679.1 - 1e-05 24.5 0.2 1.6e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP20679.1 - 2.8e-05 23.2 0.1 4.3e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KFP20679.1 - 0.0019 17.8 0.0 1.5 8.4 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP20679.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP20679.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RWD PF05773.22 KFP20680.1 - 0.017 15.4 0.2 0.024 14.9 0.2 1.2 1 0 0 1 1 1 0 RWD domain EpoR_lig-bind PF09067.10 KFP20681.1 - 0.00044 20.4 1.1 0.00083 19.5 0.3 1.8 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding fn3 PF00041.21 KFP20681.1 - 0.019 15.3 0.7 0.06 13.7 0.7 1.9 1 1 0 1 1 1 0 Fibronectin type III domain IL2RB_N1 PF18707.1 KFP20681.1 - 0.057 14.0 0.8 0.2 12.2 0.8 1.9 1 1 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 Pur_ac_phosph_N PF16656.5 KFP20681.1 - 0.2 12.2 1.4 0.79 10.3 0.4 2.4 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain IL4Ra_N PF09238.10 KFP20681.1 - 0.4 11.0 6.0 1.8 9.0 0.3 3.3 3 0 0 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal IL4Ra_N PF09238.10 KFP20683.1 - 2.3e-26 91.9 1.0 2.3e-26 91.9 1.0 2.5 2 1 0 2 2 2 1 Interleukin-4 receptor alpha chain, N-terminal fn3 PF00041.21 KFP20683.1 - 2.3e-05 24.6 0.8 9e-05 22.7 1.1 1.9 2 0 0 2 2 2 1 Fibronectin type III domain EpoR_lig-bind PF09067.10 KFP20683.1 - 0.0079 16.4 2.6 0.0079 16.4 2.6 2.4 2 1 0 2 2 2 1 Erythropoietin receptor, ligand binding SMC_Nse1 PF07574.13 KFP20684.1 - 1.7e-28 99.8 1.1 8.9e-27 94.2 1.1 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KFP20684.1 - 1.1e-09 38.4 9.2 1.1e-09 38.4 9.2 2.5 3 0 0 3 3 3 1 RING-like domain Zn_ribbon_17 PF17120.5 KFP20684.1 - 0.017 14.8 6.3 0.038 13.6 6.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KFP20684.1 - 0.087 12.7 12.1 0.044 13.7 9.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4822 PF16103.5 KFP20684.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4822) zf-ribbon_3 PF13248.6 KFP20684.1 - 0.24 10.9 6.5 0.39 10.2 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KFP20684.1 - 0.53 10.2 9.7 1.3 9.0 9.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cupin_8 PF13621.6 KFP20685.1 - 1.7e-44 152.5 0.1 2.1e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFP20685.1 - 6.3e-06 25.9 0.0 1.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KFP20685.1 - 0.0053 17.2 0.0 0.021 15.3 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Polysacc_synt_4 PF04669.13 KFP20687.1 - 0.1 12.2 1.6 0.12 11.9 1.6 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis KxDL PF10241.9 KFP20687.1 - 1 9.7 10.1 0.23 11.8 6.7 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-K PF11802.8 KFP20687.1 - 4.6 6.7 14.8 40 3.7 14.8 1.9 1 1 0 1 1 1 0 Centromere-associated protein K QSOX_Trx1 PF18108.1 KFP20689.1 - 3.2e-46 156.0 0.0 6.3e-46 155.0 0.0 1.5 1 0 0 1 1 1 1 QSOX Trx-like domain FAD_SOX PF18371.1 KFP20689.1 - 6.4e-43 145.4 0.1 5e-42 142.5 0.0 2.6 3 0 0 3 3 3 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 KFP20689.1 - 2.8e-27 95.1 0.5 1e-26 93.3 0.5 2.0 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 KFP20689.1 - 0.0095 15.9 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin zf-C3HC4_3 PF13920.6 KFP20689.1 - 0.31 10.9 1.9 12 5.8 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 KFP20689.1 - 0.4 10.8 2.6 8.1 6.7 0.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain BTB PF00651.31 KFP20690.1 - 1.1e-23 83.5 0.0 2.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BEN PF10523.9 KFP20690.1 - 4.8e-10 39.5 0.1 1.1e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 BEN domain Hamartin PF04388.12 KFP20690.1 - 0.013 14.2 1.0 0.024 13.3 1.0 1.3 1 0 0 1 1 1 0 Hamartin protein UBA PF00627.31 KFP20691.1 - 4.6e-17 61.6 1.0 1.5e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain STI1 PF17830.1 KFP20691.1 - 0.0045 16.9 0.3 0.015 15.3 0.3 1.9 1 0 0 1 1 1 1 STI1 domain UBA_3 PF09288.10 KFP20691.1 - 0.0086 15.9 0.1 1.4 8.8 0.0 2.9 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain UBA_2 PF08587.11 KFP20691.1 - 0.02 15.0 0.0 0.06 13.5 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) CAMSAP_CH PF11971.8 KFP20692.1 - 7.2e-35 118.7 0.3 1.8e-34 117.4 0.3 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CC1 PF17095.5 KFP20692.1 - 7.7e-24 83.3 5.4 7.7e-24 83.3 5.4 3.0 2 1 1 3 3 3 1 Spectrin-binding region of Ca2+-Calmodulin CAMSAP_CKK PF08683.11 KFP20692.1 - 2.7e-13 50.1 0.1 5.2e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH PF00307.31 KFP20692.1 - 0.049 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain BK_channel_a PF03493.18 KFP20693.1 - 3.8e-25 87.9 0.4 1.2e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KFP20693.1 - 1.7e-12 47.1 3.6 4.7e-12 45.7 3.6 1.7 1 0 0 1 1 1 1 Ion channel UPF0669 PF17065.5 KFP20693.1 - 0.17 11.7 0.2 0.44 10.3 0.1 1.7 2 0 0 2 2 2 0 Putative cytokine, C6ORF120 Phage_GP20 PF06810.11 KFP20694.1 - 0.0075 16.1 4.1 0.0075 16.1 4.1 2.3 2 0 0 2 2 2 1 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KFP20694.1 - 0.033 14.3 4.4 0.033 14.3 4.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 KFP20694.1 - 0.037 13.9 5.3 0.18 11.6 1.2 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Toxin_YhaV PF11663.8 KFP20694.1 - 0.054 13.5 0.3 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system RasGAP_C PF03836.15 KFP20694.1 - 0.23 11.6 5.9 0.6 10.2 5.6 1.9 1 1 0 1 1 1 0 RasGAP C-terminus DivIC PF04977.15 KFP20694.1 - 0.46 10.3 15.5 0.048 13.4 2.6 3.6 2 2 2 4 4 4 0 Septum formation initiator CASP_C PF08172.12 KFP20694.1 - 0.47 9.8 6.3 0.42 9.9 1.5 2.2 2 0 0 2 2 2 0 CASP C terminal Seryl_tRNA_N PF02403.22 KFP20694.1 - 0.62 10.3 10.1 0.54 10.5 1.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1043 PF06295.12 KFP20694.1 - 0.67 10.0 9.7 0.17 11.9 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FlaC_arch PF05377.11 KFP20694.1 - 0.8 10.1 7.0 3.1 8.2 2.7 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 KFP20694.1 - 0.82 10.1 12.9 0.48 10.9 4.1 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 KFP20694.1 - 1.3 9.2 6.6 0.41 10.8 2.8 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Spc7 PF08317.11 KFP20694.1 - 2 7.2 16.4 4.2 6.2 16.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Dzip-like_N PF13815.6 KFP20694.1 - 2.5 8.1 11.8 3.8 7.5 0.9 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal APG6_N PF17675.1 KFP20694.1 - 2.7 8.5 17.3 0.3 11.6 3.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFP20694.1 - 4.2 7.6 14.7 0.45 10.8 3.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding THOC7 PF05615.13 KFP20694.1 - 4.3 7.6 12.6 2.1 8.6 1.8 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 TnpV PF14198.6 KFP20694.1 - 4.4 7.3 7.9 7.8 6.5 0.6 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV DUF1664 PF07889.12 KFP20694.1 - 7.5 6.6 6.7 1.3 9.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 KFP20694.1 - 10 4.6 8.9 0.7 8.4 1.6 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Patched PF02460.18 KFP20695.1 - 0.0014 16.8 3.1 0.0014 16.8 3.1 2.3 2 0 0 2 2 2 1 Patched family DUF3975 PF13126.6 KFP20695.1 - 1.1 9.8 6.5 0.65 10.5 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Sterol-sensing PF12349.8 KFP20695.1 - 8 6.3 32.5 0.033 14.0 13.5 2.6 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation DUF4594 PF15266.6 KFP20696.1 - 1.6e-25 90.5 7.1 1.6e-25 90.5 7.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4594) DUF4594 PF15266.6 KFP20697.1 - 2.4e-05 24.7 0.2 2.4e-05 24.7 0.2 2.9 2 1 0 3 3 3 1 Domain of unknown function (DUF4594) Plasmodium_Vir PF05795.11 KFP20697.1 - 7.4 5.9 5.3 10 5.4 5.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PI-PLC-X PF00388.19 KFP20698.1 - 8.4e-59 197.3 0.0 2e-58 196.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFP20698.1 - 1.6e-39 134.8 1.7 1.6e-39 134.8 1.7 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFP20698.1 - 5.7e-27 94.2 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 KFP20698.1 - 1.4e-08 35.1 0.0 4e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP20698.1 - 3.5e-07 30.4 0.0 7.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain MMACHC PF16690.5 KFP20698.1 - 0.099 12.3 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Pkinase PF00069.25 KFP20699.1 - 3.6e-66 223.2 0.0 4.6e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20699.1 - 2.4e-44 151.6 0.0 3.3e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP20699.1 - 1.1e-14 54.5 0.1 2.5e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP20699.1 - 5.1e-06 26.0 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP20699.1 - 0.0003 19.7 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP20699.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I PF08311.12 KFP20700.1 - 2.1e-44 150.5 0.6 5.4e-44 149.1 0.6 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFP20700.1 - 1.4e-05 24.6 0.0 3.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain MerR-DNA-bind PF09278.11 KFP20700.1 - 0.0026 18.2 3.4 0.011 16.2 3.4 2.1 1 0 0 1 1 1 1 MerR, DNA binding DUF3987 PF13148.6 KFP20700.1 - 1 8.3 7.7 2.3 7.1 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) U79_P34 PF03064.16 KFP20700.1 - 1.8 7.9 10.5 4.4 6.6 10.5 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1690 PF07956.11 KFP20700.1 - 2.3 8.7 14.6 11 6.4 14.6 2.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cadherin PF00028.17 KFP20701.1 - 1.6e-17 63.7 1.9 2.8e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 Cadherin domain Cadherin_3 PF16184.5 KFP20701.1 - 0.001 19.0 1.6 0.023 14.7 0.1 3.2 2 1 0 2 2 2 1 Cadherin-like Hormone_2 PF00123.20 KFP20702.1 - 2.8e-23 81.5 0.1 3.3e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Peptide hormone SAND PF01342.21 KFP20703.1 - 2.6e-26 91.1 0.3 7.4e-26 89.7 0.0 2.0 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.18 KFP20703.1 - 6.4e-10 39.0 15.7 6.4e-10 39.0 15.7 2.0 2 0 0 2 2 2 1 MYND finger DUF4858 PF16150.5 KFP20703.1 - 0.3 11.1 1.7 14 5.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4858) Transmemb_17 PF09799.9 KFP20704.1 - 4.5e-28 98.0 12.6 6.8e-28 97.4 12.6 1.3 1 0 0 1 1 1 1 Predicted membrane protein PTB PF08416.13 KFP20705.1 - 1.2e-46 158.1 3.3 2.4e-46 157.2 3.3 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SAM_3 PF18016.1 KFP20705.1 - 4.7e-26 90.4 0.1 9.8e-26 89.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 KFP20705.1 - 1.2e-10 40.8 0.1 4.8e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP20705.1 - 4.9e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.23 KFP20705.1 - 3.4e-06 27.1 0.9 3.4e-06 27.1 0.9 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 KFP20705.1 - 1.4e-05 24.6 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.16 KFP20705.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SH3_3 PF08239.11 KFP20705.1 - 0.048 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain TAL_FSA PF00923.19 KFP20706.1 - 8e-98 327.3 0.0 8.9e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CEND1 PF15677.5 KFP20707.1 - 3.9e-49 167.0 12.9 4.4e-49 166.8 12.9 1.0 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 DUF1180 PF06679.12 KFP20707.1 - 0.12 12.8 3.0 0.17 12.3 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Alpha_GJ PF03229.13 KFP20707.1 - 0.15 12.6 3.5 0.067 13.7 1.3 1.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J NACHT PF05729.12 KFP20708.1 - 3.8e-35 121.2 0.0 8.1e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KFP20708.1 - 2.9e-23 82.8 0.4 2.9e-23 82.8 0.4 2.4 3 0 0 3 3 2 1 NLRC4 helical domain HD2 NOD2_WH PF17779.1 KFP20708.1 - 6.8e-16 58.3 0.1 1.7e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 NOD2 winged helix domain PYRIN PF02758.16 KFP20708.1 - 3.5e-15 55.9 0.0 1.3e-14 54.1 0.0 2.1 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain AAA_16 PF13191.6 KFP20708.1 - 8.5e-05 23.0 0.0 0.00032 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFP20708.1 - 0.00012 22.6 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFP20708.1 - 0.00084 19.7 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain FISNA PF14484.6 KFP20708.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Fish-specific NACHT associated domain AAA_22 PF13401.6 KFP20708.1 - 0.0024 18.1 0.0 0.0091 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFP20708.1 - 0.0096 15.2 0.0 0.026 13.8 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KFP20708.1 - 0.013 15.4 0.0 0.66 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFP20708.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFP20708.1 - 0.081 13.1 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFP20708.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KFP20708.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain V-set PF07686.17 KFP20709.1 - 2e-06 27.9 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain PKD_3 PF16820.5 KFP20709.1 - 0.0041 16.8 0.3 0.0052 16.5 0.3 1.2 1 1 0 1 1 1 1 PKD-like domain Ig_3 PF13927.6 KFP20709.1 - 0.057 14.0 0.3 0.064 13.9 0.3 1.2 1 0 0 1 1 1 0 Immunoglobulin domain EGF_2 PF07974.13 KFP20710.1 - 5.2e-42 141.9 210.5 6.2e-08 32.9 16.8 11.1 9 4 2 11 11 11 9 EGF-like domain I-EGF_1 PF18372.1 KFP20710.1 - 0.00015 21.8 200.3 0.0084 16.2 11.7 12.9 14 1 1 15 15 15 9 Integrin beta epidermal growth factor like domain 1 FGF PF00167.18 KFP20711.1 - 6.3e-41 139.4 0.0 7.7e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 KFP20711.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 Fascin domain CDtoxinA PF03498.14 KFP20711.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Peptidase_S8 PF00082.22 KFP20712.1 - 1.2e-96 323.5 1.2 1.8e-96 322.9 1.2 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 KFP20712.1 - 3.3e-80 268.0 0.1 8.2e-80 266.8 0.0 1.7 2 0 0 2 2 2 1 Tripeptidyl peptidase II TPPII_N PF12583.8 KFP20712.1 - 0.0006 20.4 0.2 0.0012 19.4 0.2 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal Hydrolase_4 PF12146.8 KFP20713.1 - 1e-05 24.9 0.1 0.054 12.8 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KFP20713.1 - 0.00045 19.8 0.0 0.00095 18.8 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KFP20713.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 KFP20713.1 - 0.01 15.6 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KFP20713.1 - 0.013 16.1 0.1 0.35 11.4 0.3 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFP20713.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Filament PF00038.21 KFP20714.1 - 3.7e-52 177.9 8.5 4.1e-52 177.7 8.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein SlyX PF04102.12 KFP20714.1 - 0.018 15.7 3.6 4.9 7.9 0.0 2.6 3 0 0 3 3 3 0 SlyX DUF4446 PF14584.6 KFP20714.1 - 0.13 12.2 0.7 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) bZIP_1 PF00170.21 KFP20714.1 - 0.18 11.9 9.5 1 9.5 2.0 3.2 3 1 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 KFP20714.1 - 0.23 11.2 10.3 0.39 10.5 1.2 2.7 2 1 1 3 3 3 0 Septum formation initiator DHR10 PF18595.1 KFP20714.1 - 0.38 10.8 8.1 0.55 10.3 2.6 2.2 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4140 PF13600.6 KFP20714.1 - 0.47 10.9 4.3 1.6 9.2 1.0 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.9 KFP20714.1 - 0.59 10.0 8.1 10 6.0 7.3 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain APG6_N PF17675.1 KFP20714.1 - 0.72 10.4 11.7 0.81 10.2 5.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KFP20714.1 - 1.1 9.4 7.3 3.6 7.8 3.6 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KFP20714.1 - 1.9 8.5 9.2 21 5.1 4.8 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KFP20714.1 - 3.1 8.5 7.9 16 6.2 1.1 3.0 1 1 2 3 3 3 0 Initiation control protein YabA XhlA PF10779.9 KFP20714.1 - 3.5 7.9 6.0 1.4 9.2 0.8 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Arm PF00514.23 KFP20715.1 - 8.9e-37 124.0 19.4 8.4e-10 38.4 0.1 10.8 12 0 0 12 12 12 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFP20715.1 - 4.5e-08 33.4 12.0 0.82 10.2 0.0 7.5 7 1 1 8 8 7 3 HEAT-like repeat HEAT PF02985.22 KFP20715.1 - 5.6e-08 32.4 3.7 0.1 12.9 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 KFP20715.1 - 9.6e-07 27.7 7.2 8.8e-05 21.3 1.5 2.6 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 KFP20715.1 - 1.2e-06 28.8 7.8 0.0011 19.4 0.8 4.8 3 2 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 KFP20715.1 - 2.3e-06 27.8 2.4 0.0006 19.9 0.3 3.3 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFP20715.1 - 9e-06 25.2 2.0 0.037 13.3 0.1 3.7 1 1 1 3 3 3 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 KFP20715.1 - 7.2e-05 22.7 4.2 0.012 15.7 0.1 4.8 4 2 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 KFP20715.1 - 0.00087 19.3 5.8 0.12 12.3 0.2 4.4 2 2 2 5 5 5 1 Domain of unknown function (DUF3361) PUL PF08324.11 KFP20715.1 - 0.0009 18.6 3.7 0.0014 17.9 0.1 2.5 2 1 0 2 2 2 1 PUL domain Arm_2 PF04826.13 KFP20715.1 - 0.0058 16.1 6.2 0.64 9.4 0.1 4.4 2 2 2 4 4 4 1 Armadillo-like RasGEF_N_2 PF14663.6 KFP20715.1 - 0.014 15.8 6.1 3 8.3 0.1 4.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain mRNA_stabil PF13929.6 KFP20715.1 - 1.1 8.2 3.7 6.1 5.7 0.2 3.1 2 1 1 3 3 3 0 mRNA stabilisation FKBP_C PF00254.28 KFP20716.1 - 1.2e-107 352.4 0.0 1.9e-28 98.6 0.0 4.3 4 0 0 4 4 4 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 KFP20716.1 - 7.6e-09 34.5 0.4 0.00084 18.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP20716.1 - 1e-08 34.3 1.4 0.00073 18.9 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP20716.1 - 1.2e-06 28.8 0.1 0.028 14.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP20716.1 - 1.7e-06 27.5 0.1 0.12 12.4 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFP20716.1 - 0.011 15.6 0.1 0.03 14.2 0.1 1.8 1 1 1 2 2 2 0 EF-hand domain pair UMPH-1 PF05822.12 KFP20717.1 - 9.9e-121 401.9 0.4 1.2e-120 401.7 0.4 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KFP20717.1 - 1.9e-05 25.1 0.0 4.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFP20717.1 - 0.0094 15.4 0.6 0.071 12.5 0.1 2.3 2 1 0 2 2 2 1 Putative Phosphatase BACK PF07707.15 KFP20718.1 - 3.4e-27 94.5 1.4 7.7e-27 93.4 1.4 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 KFP20718.1 - 2.1e-20 72.3 1.8 5.2e-05 23.4 0.0 4.8 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KFP20718.1 - 2.4e-14 52.6 13.8 0.0023 17.5 0.4 5.8 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KFP20718.1 - 2.8e-12 46.4 0.0 0.31 11.1 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP20718.1 - 7.5e-09 35.2 0.9 0.032 14.2 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KFP20718.1 - 1.1e-06 28.8 0.1 0.018 15.3 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain LVIVD PF08309.11 KFP20718.1 - 0.25 10.7 1.2 14 5.1 0.3 2.5 2 0 0 2 2 2 0 LVIVD repeat Citrate_bind PF16114.5 KFP20719.1 - 6.1e-91 302.7 0.1 1.1e-90 301.9 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KFP20719.1 - 4.4e-23 81.9 0.0 5.2e-20 71.8 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KFP20719.1 - 2.4e-13 50.2 0.1 5.1e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KFP20719.1 - 4.7e-11 43.2 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KFP20719.1 - 4.1e-07 29.8 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KFP20719.1 - 0.00025 20.9 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 KFP20719.1 - 0.022 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_12 PF13424.6 KFP20720.1 - 1e-16 61.0 7.8 6e-06 26.5 1.4 4.2 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP20720.1 - 6.2e-14 50.9 11.3 0.19 11.9 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFP20720.1 - 2.5e-12 46.1 18.0 0.0096 15.7 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP20720.1 - 2.9e-11 43.3 5.0 6.1e-11 42.3 4.5 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 KFP20720.1 - 1.8e-10 40.2 15.4 0.16 12.2 0.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFP20720.1 - 2.6e-09 36.5 8.8 0.042 13.9 0.0 7.2 6 1 1 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KFP20720.1 - 3.3e-05 23.7 5.2 0.00022 21.0 1.7 2.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 KFP20720.1 - 0.00038 20.9 11.3 6.2 7.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFP20720.1 - 0.00043 20.4 1.7 0.43 10.6 0.0 3.9 3 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KFP20720.1 - 0.00069 19.8 6.1 0.02 15.1 0.5 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KFP20720.1 - 0.012 15.9 7.8 1.8 9.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP20720.1 - 3 7.8 8.1 4.3 7.3 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat CNPase PF05881.12 KFP20721.1 - 2.1e-113 377.7 0.1 2.9e-113 377.2 0.1 1.2 1 0 0 1 1 1 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_14 PF13173.6 KFP20721.1 - 5.1e-05 23.3 0.4 0.0019 18.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain 6PF2K PF01591.18 KFP20721.1 - 0.00016 21.1 0.1 0.07 12.4 0.1 2.2 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 KFP20721.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KFP20721.1 - 0.00026 21.2 0.0 0.00082 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFP20721.1 - 0.00029 21.1 0.6 0.012 15.9 0.4 2.7 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFP20721.1 - 0.00049 20.6 0.0 0.00099 19.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter CPT PF07931.12 KFP20721.1 - 0.00094 19.1 0.0 0.0052 16.6 0.0 2.0 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KFP20721.1 - 0.001 19.5 0.3 0.0097 16.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KFP20721.1 - 0.0025 18.3 0.0 0.0048 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFP20721.1 - 0.0031 17.9 0.0 0.0078 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP20721.1 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFP20721.1 - 0.0096 15.1 0.9 0.22 10.7 0.9 2.3 1 1 0 1 1 1 1 NB-ARC domain KTI12 PF08433.10 KFP20721.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 KFP20721.1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFP20721.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KFP20721.1 - 0.036 14.5 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFP20721.1 - 0.05 13.3 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain TK PF00265.18 KFP20721.1 - 0.099 12.5 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Thymidine kinase Viral_helicase1 PF01443.18 KFP20721.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KFP20721.1 - 0.11 12.4 0.1 1.2 9.0 0.0 2.1 1 1 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 KFP20721.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KFP20721.1 - 0.14 12.7 0.5 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KFP20721.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KFP20721.1 - 0.24 10.4 0.1 3.7 6.5 0.0 2.2 1 1 1 2 2 2 0 Type II/IV secretion system protein Ras PF00071.22 KFP20722.1 - 3.2e-25 88.6 0.2 3.6e-25 88.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20722.1 - 4.8e-11 42.9 0.2 8.9e-11 42.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20722.1 - 1.7e-07 30.9 0.1 2.1e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP20722.1 - 8.9e-06 25.8 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP20722.1 - 1.7e-05 24.5 0.2 0.0024 17.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFP20722.1 - 0.00014 22.0 0.6 0.00049 20.2 0.4 1.9 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 KFP20722.1 - 0.0012 18.8 0.3 0.74 9.7 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase DUF2121 PF09894.9 KFP20722.1 - 0.0013 18.3 0.2 0.015 14.8 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) G-alpha PF00503.20 KFP20722.1 - 0.071 12.3 0.9 1.4 8.0 0.1 2.1 1 1 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KFP20722.1 - 0.08 13.3 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain UPF0113 PF03657.13 KFP20722.1 - 0.088 13.1 0.2 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 UPF0113 PUA domain DUF2677 PF10838.8 KFP20722.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) DUF3740 PF12548.8 KFP20723.1 - 6.2e-55 185.7 0.9 6.2e-55 185.7 0.9 2.3 3 0 0 3 3 3 1 Sulfatase protein Sulfatase PF00884.23 KFP20723.1 - 9.9e-49 166.4 1.4 1.5e-48 165.8 1.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFP20723.1 - 0.0077 15.8 0.2 3.7 7.0 0.0 2.5 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFP20723.1 - 0.04 14.2 0.0 6.9 7.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) TPR_MLP1_2 PF07926.12 KFP20723.1 - 0.37 10.9 4.1 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KFP20723.1 - 8.1 6.7 8.0 2.1 8.7 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) DEP PF00610.21 KFP20724.1 - 3.4e-42 142.3 0.2 2.9e-21 75.3 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.20 KFP20724.1 - 1.1e-36 126.8 1.3 6.7e-36 124.2 0.1 3.0 3 0 0 3 3 3 1 RhoGEF domain PDZ PF00595.24 KFP20724.1 - 1.7e-08 34.7 0.0 0.0047 17.2 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP20724.1 - 2.3e-08 33.7 0.0 0.00063 19.5 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KFP20724.1 - 2.5e-05 24.5 0.0 0.3 11.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PH PF00169.29 KFP20724.1 - 3.2e-05 24.4 0.2 0.00022 21.7 0.2 2.5 2 0 0 2 2 2 1 PH domain PH_10 PF15411.6 KFP20724.1 - 0.00068 19.9 1.4 0.0028 17.9 0.4 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UPF1_Zn_bind PF09416.10 KFP20724.1 - 0.011 15.7 0.0 0.039 13.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) IQ_SEC7_PH PF16453.5 KFP20724.1 - 0.023 14.7 0.1 0.073 13.0 0.1 1.8 1 0 0 1 1 1 0 PH domain Y_phosphatase PF00102.27 KFP20726.1 - 2.3e-147 488.8 1.7 8e-81 271.1 0.1 2.6 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KFP20726.1 - 4.7e-29 100.6 2.2 2.6e-11 43.7 0.0 5.6 5 0 0 5 5 5 3 Fibronectin type III domain MAM PF00629.23 KFP20726.1 - 3.8e-24 85.4 0.0 1e-23 84.1 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DSPc PF00782.20 KFP20726.1 - 4.7e-09 36.2 0.1 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP20726.1 - 7.4e-05 22.8 0.0 0.024 14.6 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP20726.1 - 0.00013 22.1 0.0 0.8 9.8 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Amnionless PF14828.6 KFP20726.1 - 0.016 14.0 0.2 0.028 13.2 0.2 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KFP20726.1 - 0.025 15.4 0.0 0.061 14.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 KFP20726.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J I-set PF07679.16 KFP20726.1 - 0.043 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP20726.1 - 0.072 13.4 1.7 0.17 12.2 0.1 2.6 2 0 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 KFP20726.1 - 0.087 13.0 0.5 0.22 11.7 0.1 1.9 2 0 0 2 2 1 0 Immunoglobulin domain COLFI PF01410.18 KFP20727.1 - 1.6e-56 191.2 0.0 1.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain CDI PF02234.19 KFP20728.1 - 2.8e-21 75.4 3.8 3.1e-21 75.3 3.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Pkinase PF00069.25 KFP20729.1 - 4.1e-59 200.1 0.2 4.1e-59 200.1 0.2 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20729.1 - 3.4e-29 101.9 2.5 1.3e-20 73.8 0.2 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFP20729.1 - 2.1e-07 31.5 1.4 5.2e-07 30.3 0.8 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFP20729.1 - 1.6e-05 24.0 0.6 3.6e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP20729.1 - 5.8e-05 22.6 0.4 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP20729.1 - 0.0006 19.8 0.1 0.036 14.0 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP20729.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFP20729.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MEKHLA PF08670.11 KFP20729.1 - 0.18 11.7 1.3 1.5 8.7 0.8 2.2 2 0 0 2 2 2 0 MEKHLA domain SAM_PNT PF02198.16 KFP20730.1 - 3.2e-19 68.7 0.1 3.3e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ion_trans PF00520.31 KFP20731.1 - 1.9e-51 174.7 6.2 2.5e-51 174.3 6.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP20731.1 - 2.4e-28 98.3 0.0 4e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP20731.1 - 1.1e-13 50.9 5.8 1.1e-13 50.9 5.8 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP20731.1 - 0.0014 17.4 0.9 0.0019 17.0 0.3 1.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KFP20732.1 - 1e-51 175.6 8.2 1.4e-51 175.1 8.2 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP20732.1 - 2e-28 98.6 0.0 3.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP20732.1 - 1.6e-14 53.6 4.7 1.6e-14 53.6 4.7 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP20732.1 - 0.013 14.2 0.9 0.013 14.2 0.9 1.6 2 0 0 2 2 2 0 Polycystin cation channel Sigma_reg_N PF13800.6 KFP20732.1 - 0.094 13.0 0.7 10 6.5 0.0 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ion_trans PF00520.31 KFP20733.1 - 2.8e-50 170.9 13.4 3.5e-50 170.5 13.4 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP20733.1 - 9.9e-24 83.5 0.1 2.4e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP20733.1 - 2.1e-13 50.0 5.8 2.1e-13 50.0 5.8 2.9 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 KFP20733.1 - 0.00046 19.0 0.5 0.00046 19.0 0.5 2.4 1 1 2 3 3 3 1 Polycystin cation channel DUF423 PF04241.15 KFP20733.1 - 0.49 10.6 3.7 0.7 10.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF202 PF02656.15 KFP20733.1 - 0.94 10.0 5.7 1.3e+02 3.1 5.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Sigma_reg_N PF13800.6 KFP20733.1 - 5.8 7.3 8.1 16 5.8 0.1 3.7 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DctQ PF04290.12 KFP20733.1 - 6.3 6.7 8.6 0.48 10.3 0.5 2.9 2 2 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component LAMTOR5 PF16672.5 KFP20734.1 - 4.8e-18 64.9 0.1 5.2e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 MFS_1 PF07690.16 KFP20735.1 - 1.9e-33 115.8 34.0 5.7e-18 64.9 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.8 KFP20735.1 - 2.2 8.6 10.1 5.4 7.4 1.8 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) SPOC PF07744.13 KFP20736.1 - 1.4e-38 132.1 0.0 2.3e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KFP20736.1 - 8.7e-20 70.3 0.0 1.5e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFP20736.1 - 7.8e-07 29.0 0.0 0.00064 19.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP20736.1 - 0.00051 20.1 0.0 0.0054 16.8 0.0 2.3 1 1 1 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KFP20736.1 - 0.036 14.2 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif K_channel_TID PF07941.11 KFP20736.1 - 2.7 8.5 16.2 0.051 14.0 6.2 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIS_C PF01096.18 KFP20737.1 - 2.2e-13 49.8 4.7 6.9e-12 45.0 1.7 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFP20737.1 - 7.1e-11 41.8 3.0 7.1e-11 41.8 3.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 KFP20737.1 - 0.04 13.9 2.3 0.04 13.9 2.3 2.6 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger TF_Zn_Ribbon PF08271.12 KFP20737.1 - 0.051 13.1 1.5 0.43 10.1 0.2 2.9 2 1 1 3 3 3 0 TFIIB zinc-binding CpXC PF14353.6 KFP20737.1 - 0.072 13.1 6.2 0.57 10.2 0.4 2.3 1 1 0 2 2 2 0 CpXC protein DUF3268 PF11672.8 KFP20737.1 - 0.52 10.6 5.0 3.5 8.0 0.6 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain DNA_RNApol_7kD PF03604.13 KFP20737.1 - 1.4 8.7 7.0 4.3 7.1 0.0 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Rubredoxin_2 PF18073.1 KFP20737.1 - 2.5 7.9 11.6 5.3 6.9 1.3 3.2 3 0 0 3 3 3 0 Rubredoxin metal binding domain Zn_Tnp_IS1595 PF12760.7 KFP20737.1 - 7.3 6.7 10.1 9.4 6.3 4.5 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain RGS-like PF09128.11 KFP20738.1 - 5.4e-66 221.9 0.1 1.9e-65 220.1 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain PH_16 PF17838.1 KFP20738.1 - 3.8e-43 146.3 0.2 8.8e-43 145.1 0.2 1.6 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KFP20738.1 - 3.7e-37 128.3 4.8 1e-36 126.9 4.8 1.8 1 0 0 1 1 1 1 RhoGEF domain PDZ PF00595.24 KFP20738.1 - 1.3e-14 54.3 0.2 2.7e-14 53.3 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP20738.1 - 1.5e-12 47.1 0.1 3.8e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP20738.1 - 2.8e-08 34.0 0.1 8.4e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain RGS PF00615.19 KFP20738.1 - 4.1e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Tricorn_PDZ PF14685.6 KFP20738.1 - 0.16 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ribosomal_S30AE PF02482.19 KFP20738.1 - 0.17 12.7 0.7 4.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Clat_adaptor_s PF01217.20 KFP20740.1 - 5.5e-57 191.7 2.6 6.4e-57 191.5 2.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF629 PF04780.12 KFP20740.1 - 0.0017 17.0 0.3 0.0021 16.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) PulA_N1 PF17999.1 KFP20740.1 - 0.082 13.6 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain RuBisCO_small PF00101.20 KFP20740.1 - 0.12 12.4 1.0 0.17 11.9 0.2 1.7 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain IL17 PF06083.11 KFP20742.1 - 8.4e-31 106.3 1.4 1.3e-30 105.7 0.8 1.6 2 0 0 2 2 2 1 Interleukin-17 IL17 PF06083.11 KFP20743.1 - 9.2e-31 106.2 0.2 1.5e-30 105.5 0.2 1.3 1 0 0 1 1 1 1 Interleukin-17 MCM PF00493.23 KFP20744.1 - 2.7e-96 321.0 0.0 4.4e-96 320.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP20744.1 - 3.8e-34 117.3 0.3 3.8e-34 117.3 0.3 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KFP20744.1 - 1.3e-21 76.8 3.1 3.5e-21 75.4 3.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFP20744.1 - 1.3e-09 38.6 0.7 3.6e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFP20744.1 - 7.2e-07 28.8 0.0 4.5e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFP20744.1 - 0.0025 17.7 0.0 0.0075 16.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP20744.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFP20744.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain CPSF100_C PF13299.6 KFP20744.1 - 0.52 10.5 4.7 1.1 9.4 4.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HlyIII PF03006.20 KFP20745.1 - 1.3e-50 172.2 17.7 1.3e-50 172.2 17.7 1.3 2 0 0 2 2 2 1 Haemolysin-III related DUF5504 PF17608.2 KFP20745.1 - 0.011 15.8 5.1 0.029 14.5 5.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DUF1126 PF06565.12 KFP20746.1 - 8.6e-106 346.9 3.0 3.6e-35 120.0 0.4 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_6 PF13405.6 KFP20746.1 - 0.0035 17.2 0.0 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFP20746.1 - 0.011 15.3 0.0 0.093 12.3 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF5580 PF17743.1 KFP20746.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) TRAM_LAG1_CLN8 PF03798.16 KFP20747.1 - 9.4e-23 81.0 16.7 9.4e-23 81.0 16.7 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFP20747.1 - 2.1e-15 56.1 0.2 2.1e-15 56.1 0.2 2.4 2 0 0 2 2 2 1 TRAM1-like protein RhodobacterPufX PF11511.8 KFP20747.1 - 0.11 12.1 1.8 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF2207 PF09972.9 KFP20747.1 - 0.65 8.7 5.2 0.16 10.7 2.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 KFP20747.1 - 1.3 10.0 6.5 14 6.7 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) ECF_trnsprt PF12822.7 KFP20747.1 - 5.7 7.0 8.1 29 4.7 8.1 2.2 1 1 0 1 1 1 0 ECF transporter, substrate-specific component VHS PF00790.19 KFP20750.1 - 2e-39 134.6 1.4 1.6e-38 131.8 0.1 2.3 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KFP20750.1 - 7.5e-19 67.1 0.1 1.4e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP20750.1 - 3.3e-12 46.1 0.1 6.8e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP20750.1 - 4e-12 45.6 0.0 7.8e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KFP20750.1 - 1.9e-05 24.3 2.0 4.5e-05 23.1 2.0 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif FH2 PF02181.23 KFP20751.1 - 6.3e-103 344.8 10.6 6.3e-103 344.8 10.6 3.5 5 0 0 5 5 5 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 KFP20751.1 - 1.1e-49 168.7 16.1 1.1e-49 168.7 16.1 2.8 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KFP20751.1 - 1.3e-22 80.3 3.1 2.2e-13 50.2 0.5 5.4 4 1 0 4 4 4 2 Diaphanous GTPase-binding Domain DsrC PF04358.13 KFP20751.1 - 0.35 11.4 3.8 0.53 10.8 1.5 2.6 2 0 0 2 2 2 0 DsrC like protein Cob_adeno_trans PF01923.18 KFP20751.1 - 0.93 9.6 6.0 9.8 6.3 4.4 2.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase SOBP PF15279.6 KFP20751.1 - 7.5 7.1 8.5 0.61 10.6 1.5 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein FF PF01846.19 KFP20752.1 - 6e-47 157.6 23.7 3.5e-16 59.1 0.5 6.2 5 0 0 5 5 5 5 FF domain WW PF00397.26 KFP20752.1 - 1.8e-19 69.5 19.5 2.9e-10 40.0 8.0 2.7 2 0 0 2 2 2 2 WW domain TPR_6 PF13174.6 KFP20752.1 - 9.6 7.1 6.3 30 5.5 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L10 PF00466.20 KFP20753.1 - 4.3e-08 33.2 0.3 6.9e-08 32.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 7tm_4 PF13853.6 KFP20754.1 - 1.6e-41 142.9 16.7 1.9e-41 142.6 16.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20754.1 - 7.8e-30 104.1 15.5 1e-29 103.7 15.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP20754.1 - 0.14 11.8 13.0 0.098 12.3 10.6 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx IRK_C PF17655.1 KFP20755.1 - 5.5e-66 221.5 0.0 7.8e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP20755.1 - 6.9e-57 191.2 0.5 1.1e-56 190.5 0.5 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DUF2182 PF09948.9 KFP20755.1 - 0.041 13.8 0.5 0.076 12.9 0.5 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Ion_trans_2 PF07885.16 KFP20755.1 - 0.045 13.7 4.2 0.1 12.6 4.1 1.7 1 1 0 1 1 1 0 Ion channel Acetyltransf_1 PF00583.25 KFP20756.1 - 2.4e-10 40.7 0.0 3.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP20756.1 - 8.1e-08 32.3 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFP20756.1 - 2.6e-07 31.0 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFP20756.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SIX1_SD PF16878.5 KFP20757.1 - 5.3e-46 155.7 0.8 2.4e-44 150.4 0.0 2.8 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KFP20757.1 - 6e-14 51.6 1.5 1.3e-13 50.5 1.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP20757.1 - 1.5e-09 37.5 0.7 4e-09 36.2 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KFP20757.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MAT1 PF06391.13 KFP20758.1 - 3.7e-64 216.3 21.5 4.2e-64 216.1 21.5 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Met_10 PF02475.16 KFP20759.1 - 3.8e-66 222.7 0.0 6.2e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KFP20759.1 - 0.00038 20.1 0.0 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 KFP20759.1 - 0.00063 19.0 0.0 0.006 15.8 0.0 2.1 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 KFP20759.1 - 0.00097 18.9 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase tRNA_U5-meth_tr PF05958.11 KFP20759.1 - 0.0034 16.4 0.0 0.044 12.8 0.0 2.1 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 KFP20759.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aa_trans PF01490.18 KFP20760.1 - 4.3e-54 183.8 27.3 5.3e-54 183.5 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein C1_1 PF00130.22 KFP20761.1 - 8.1e-25 86.5 28.9 5e-17 61.5 6.4 2.5 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2321 PF10083.9 KFP20761.1 - 0.0024 17.5 3.6 0.92 9.1 0.0 2.4 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2321) C1_2 PF03107.16 KFP20761.1 - 0.006 16.9 2.6 0.006 16.9 2.6 2.9 2 1 0 2 2 2 1 C1 domain SpmSyn_N PF17950.1 KFP20761.1 - 0.13 12.5 0.2 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal 7tm_4 PF13853.6 KFP20762.1 - 5.6e-46 157.5 13.8 6.5e-46 157.3 13.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20762.1 - 2.3e-27 96.0 15.9 3.2e-27 95.5 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP20762.1 - 0.0084 15.8 14.2 0.017 14.8 14.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP20762.1 - 0.011 15.1 13.0 0.018 14.4 13.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP20763.1 - 1.6e-43 149.5 11.9 1.9e-43 149.2 11.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20763.1 - 2.2e-28 99.3 14.8 3e-28 98.9 14.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP20763.1 - 5.6e-05 22.6 4.5 5.6e-05 22.6 4.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP20763.1 - 0.066 12.8 11.9 0.12 12.0 11.9 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP20764.1 - 1.2e-44 153.2 9.9 1.4e-44 152.9 9.9 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP20764.1 - 5.4e-29 101.3 13.6 7.4e-29 100.9 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP20764.1 - 1.7e-05 24.3 3.5 1.7e-05 24.3 3.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP20764.1 - 0.017 14.8 9.4 0.033 13.8 9.4 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RVT_1 PF00078.27 KFP20766.1 - 0.0021 17.6 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_3 PF13920.6 KFP20767.1 - 2.9e-07 30.2 9.1 2.9e-07 30.2 9.1 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP20767.1 - 4.6e-06 26.4 12.1 4.6e-06 26.4 12.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP20767.1 - 1e-05 25.4 10.9 1e-05 25.4 10.9 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP20767.1 - 1.6e-05 24.7 13.5 1.6e-05 24.7 13.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP20767.1 - 8.1e-05 22.9 12.2 8.1e-05 22.9 12.2 3.9 3 1 3 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 KFP20767.1 - 0.00031 20.6 9.9 0.00031 20.6 9.9 3.8 4 0 0 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP20767.1 - 0.0041 17.0 9.6 0.0041 17.0 9.6 3.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KFP20767.1 - 1.6 8.6 21.3 0.15 11.9 4.0 3.4 3 0 0 3 3 3 0 zf-RING of BARD1-type protein HSNSD PF12062.8 KFP20768.1 - 1.6e-243 808.9 0.0 2.1e-243 808.5 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KFP20768.1 - 3e-42 145.0 0.0 4.8e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP20768.1 - 4.9e-09 36.9 0.3 9.4e-05 22.9 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family Ank_2 PF12796.7 KFP20769.1 - 1.7e-29 102.2 4.0 5.7e-12 46.1 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP20769.1 - 6.4e-20 71.0 0.7 1.4e-10 41.2 0.2 3.4 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP20769.1 - 3.6e-17 62.5 0.1 2.4e-08 34.3 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFP20769.1 - 7.3e-15 54.7 1.8 8.3e-05 22.9 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KFP20769.1 - 2.1e-10 39.9 0.5 0.00099 19.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DUF1843 PF08898.10 KFP20769.1 - 0.014 15.9 0.1 0.058 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Glyco_trans_1_4 PF13692.6 KFP20769.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 zf-RING_2 PF13639.6 KFP20770.1 - 3.5e-12 46.4 5.6 4.8e-12 46.0 5.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP20770.1 - 2.2e-11 43.3 4.6 2.2e-11 43.3 4.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP20770.1 - 9.1e-08 32.0 2.8 1.7e-07 31.2 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFP20770.1 - 4.5e-07 29.6 6.0 6.5e-07 29.1 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP20770.1 - 2.3e-06 27.8 7.9 1.2e-05 25.4 7.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP20770.1 - 3e-06 27.0 2.2 4.3e-06 26.5 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP20770.1 - 3.6e-06 26.7 3.5 5.7e-06 26.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP20770.1 - 3e-05 23.9 1.7 4.8e-05 23.2 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFP20770.1 - 5.1e-05 22.8 2.7 8.4e-05 22.1 2.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFP20770.1 - 0.00012 21.9 2.2 0.00018 21.3 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP20770.1 - 0.062 13.5 3.7 0.11 12.6 3.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KFP20770.1 - 0.084 12.8 1.6 0.13 12.1 1.6 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein BCDHK_Adom3 PF10436.9 KFP20770.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase zf-C3H2C3 PF17122.5 KFP20770.1 - 0.15 12.1 3.9 0.37 10.9 3.9 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KFP20770.1 - 0.19 11.9 8.2 4.4 7.5 8.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KFP20770.1 - 0.36 10.9 6.9 4.1 7.5 7.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3808 PF10300.9 KFP20771.1 - 7.2e-155 516.3 2.6 7.2e-155 516.3 2.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KFP20771.1 - 4.5e-10 39.7 2.0 7.1e-07 29.4 0.7 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP20771.1 - 7.4e-10 39.3 1.6 0.0017 18.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP20771.1 - 1e-05 25.9 4.5 0.0097 16.7 0.1 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP20771.1 - 7.1e-05 22.6 10.8 0.011 15.8 1.7 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP20771.1 - 0.0001 21.9 5.4 0.13 12.2 1.7 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP20771.1 - 0.00048 20.6 9.6 0.03 14.8 1.6 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP20771.1 - 0.00065 20.2 3.7 0.019 15.6 1.3 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP20771.1 - 0.0007 19.4 7.0 0.014 15.3 0.8 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP20771.1 - 0.0012 18.9 6.0 0.57 10.5 0.5 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP20771.1 - 0.0016 17.8 0.5 0.19 11.1 0.4 2.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KFP20771.1 - 0.0043 17.0 2.0 0.015 15.3 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFP20771.1 - 0.018 15.6 0.1 1.6 9.6 0.1 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat T3SS_ATPase_C PF18269.1 KFP20771.1 - 0.055 13.3 0.2 0.44 10.4 0.0 2.5 3 0 0 3 3 3 0 T3SS EscN ATPase C-terminal domain SOAR PF16533.5 KFP20771.1 - 0.38 10.7 0.1 0.38 10.7 0.1 2.6 3 0 0 3 3 3 0 STIM1 Orai1-activating region EF-hand_4 PF12763.7 KFP20772.1 - 4.1e-41 139.2 0.4 1.2e-23 83.1 0.0 4.0 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFP20772.1 - 5.1e-12 44.4 5.0 0.0021 17.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP20772.1 - 2.1e-07 30.3 1.9 0.41 10.7 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KFP20772.1 - 1.9e-06 28.2 3.1 0.47 11.0 0.0 4.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP20772.1 - 2.8e-06 27.1 3.5 0.067 13.0 0.4 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP20772.1 - 5.1e-06 25.7 3.4 0.46 10.1 0.0 3.8 3 0 0 3 3 3 2 EF hand Spc7 PF08317.11 KFP20772.1 - 0.00019 20.5 24.1 0.00019 20.5 24.1 2.8 2 1 1 3 3 3 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KFP20772.1 - 0.0025 17.8 21.8 0.0025 17.8 21.8 4.9 3 1 3 6 6 4 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KFP20772.1 - 0.0039 17.4 17.5 0.0039 17.4 17.5 4.5 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KFP20772.1 - 0.019 15.5 56.7 0.08 13.5 14.4 3.7 2 1 1 3 3 3 0 Apg6 coiled-coil region ESSS PF10183.9 KFP20772.1 - 0.099 12.9 0.5 0.24 11.6 0.5 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA_13 PF13166.6 KFP20772.1 - 0.11 11.1 30.8 0.24 10.0 28.4 2.2 1 1 0 1 1 1 0 AAA domain UIM PF02809.20 KFP20772.1 - 0.19 11.7 6.1 0.48 10.5 3.5 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Fib_alpha PF08702.10 KFP20772.1 - 0.27 11.4 26.3 0.27 11.4 10.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 KFP20772.1 - 0.43 8.7 39.7 0.017 13.3 22.6 2.2 1 1 1 2 2 2 0 HOOK protein TMPIT PF07851.13 KFP20772.1 - 0.95 8.6 27.9 0.15 11.3 14.9 2.3 1 1 1 2 2 2 0 TMPIT-like protein RasGAP_C PF03836.15 KFP20772.1 - 1.4 9.1 26.9 0.87 9.7 4.9 3.3 1 1 2 3 3 3 0 RasGAP C-terminus ADIP PF11559.8 KFP20772.1 - 2.2 8.4 43.3 0.051 13.7 6.5 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 KFP20772.1 - 3.3 7.2 34.4 0.25 10.8 27.9 2.1 1 1 1 2 2 2 0 Leucine zipper Laminin_II PF06009.12 KFP20772.1 - 4 7.4 22.4 16 5.5 3.0 2.8 1 1 1 2 2 2 0 Laminin Domain II KxDL PF10241.9 KFP20772.1 - 7.3 7.0 24.3 0.23 11.7 2.1 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 KFP20772.1 - 7.6 6.6 22.9 0.42 10.6 6.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Oxysterol_BP PF01237.18 KFP20773.1 - 3.2e-84 282.9 3.3 3.5e-82 276.2 3.3 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFP20773.1 - 0.00027 21.4 0.0 0.001 19.6 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP20773.1 - 0.0047 17.3 0.4 0.013 15.9 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KFP20773.1 - 0.053 13.8 0.2 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Sec3-PIP2_bind PF15277.6 KFP20773.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Peptidase_M16_M PF16187.5 KFP20774.1 - 1.9e-86 289.8 1.1 3.2e-86 289.1 1.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFP20774.1 - 1e-41 142.4 0.4 2.5e-40 137.9 0.0 2.8 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFP20774.1 - 2e-35 122.5 2.3 8.3e-21 74.8 0.1 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain SDA1 PF05285.12 KFP20774.1 - 0.024 14.1 22.0 0.036 13.5 22.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KFP20774.1 - 0.27 9.4 23.9 0.43 8.7 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KFP20774.1 - 0.36 9.2 17.7 0.73 8.2 17.7 1.4 1 0 0 1 1 1 0 Mpp10 protein Ras PF00071.22 KFP20775.1 - 5.4e-61 204.9 0.5 6.5e-61 204.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20775.1 - 4e-34 117.4 0.6 5.7e-34 116.9 0.6 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20775.1 - 5.2e-13 48.8 0.2 6.3e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFP20775.1 - 4e-05 23.1 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP20775.1 - 0.00022 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP20775.1 - 0.00046 19.8 0.1 0.0015 18.1 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFP20775.1 - 0.00052 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFP20775.1 - 0.0083 15.7 0.0 3.5 7.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B G-alpha PF00503.20 KFP20775.1 - 0.016 14.4 0.3 5.6 6.0 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KFP20775.1 - 0.017 15.0 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF2757 PF10955.8 KFP20775.1 - 0.023 15.0 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) AAA_24 PF13479.6 KFP20775.1 - 0.046 13.4 0.4 0.12 12.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFP20775.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Thioredoxin_7 PF13899.6 KFP20776.1 - 2.3e-18 66.1 0.0 3.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KFP20776.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP20776.1 - 0.0003 21.2 0.0 0.00049 20.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KFP20776.1 - 0.0035 17.3 0.1 0.0041 17.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.6 KFP20776.1 - 0.0035 17.6 0.1 0.015 15.6 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KFP20776.1 - 0.0086 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KFP20776.1 - 0.0095 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFP20776.1 - 0.024 14.6 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 KFP20776.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin NAC PF01849.18 KFP20777.1 - 4.8e-25 87.3 0.1 8.3e-25 86.5 0.1 1.4 1 0 0 1 1 1 1 NAC domain DUF3480 PF11979.8 KFP20778.1 - 7.9e-176 584.2 0.0 1.1e-175 583.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) SARA PF11409.8 KFP20778.1 - 5.9e-19 68.0 10.6 5.9e-19 68.0 10.6 2.9 3 0 0 3 3 3 1 Smad anchor for receptor activation (SARA) FYVE PF01363.21 KFP20778.1 - 4.6e-18 65.1 15.9 4.6e-18 65.1 15.9 2.3 2 0 0 2 2 2 1 FYVE zinc finger Band_3_cyto PF07565.13 KFP20778.1 - 0.01 15.6 0.2 0.031 14.1 0.2 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain cPLA2_C2 PF18695.1 KFP20778.1 - 0.019 15.0 0.3 0.29 11.1 0.1 2.8 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain C2 PF00168.30 KFP20779.1 - 3.1e-09 37.0 0.0 6.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF1771 PF08590.10 KFP20779.1 - 8 6.9 25.7 0.12 12.7 0.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) AAA PF00004.29 KFP20780.1 - 1.5e-17 64.2 0.0 3.5e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KFP20780.1 - 1.3e-15 57.1 0.2 3.2e-15 55.9 0.2 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 KFP20780.1 - 1.7e-11 44.8 0.0 1.2e-10 42.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP20780.1 - 2.2e-11 44.2 0.0 6.7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KFP20780.1 - 7.8e-10 38.8 0.1 3.3e-09 36.8 0.1 2.1 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 KFP20780.1 - 1.8e-09 37.5 0.1 6.4e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KFP20780.1 - 0.00035 20.9 0.1 0.001 19.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFP20780.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFP20780.1 - 0.0014 18.6 0.0 0.0046 16.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 KFP20780.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 KFP20780.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DNase_II PF03265.15 KFP20780.1 - 1.9 7.7 7.1 0.15 11.3 2.1 1.6 2 0 0 2 2 2 0 Deoxyribonuclease II PRP38 PF03371.15 KFP20781.1 - 6.8e-41 140.0 1.5 8.5e-41 139.7 1.5 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KFP20781.1 - 4.2e-07 30.5 37.6 4.2e-07 30.5 37.6 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2457 PF10446.9 KFP20781.1 - 5.1 6.1 40.7 12 4.9 40.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) PAP_assoc PF03828.19 KFP20782.1 - 1.8e-30 104.9 0.7 9.8e-16 57.7 0.2 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.23 KFP20782.1 - 1e-11 44.3 21.7 4.6e-05 23.3 1.0 4.0 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.23 KFP20782.1 - 4.5e-10 39.7 0.0 1.1e-07 32.1 0.0 2.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC_4 PF14392.6 KFP20782.1 - 2.5e-05 23.9 14.9 0.25 11.1 0.6 3.7 3 0 0 3 3 3 3 Zinc knuckle Polbeta PF18765.1 KFP20782.1 - 4.8e-05 23.4 0.0 0.055 13.6 0.0 2.6 2 0 0 2 2 2 2 Polymerase beta, Nucleotidyltransferase zf-CCHC_2 PF13696.6 KFP20782.1 - 0.003 17.4 38.8 0.055 13.3 6.7 5.5 5 0 0 5 5 5 3 Zinc knuckle Ubiq_cyt_C_chap PF03981.12 KFP20782.1 - 0.098 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone zf-CCHC_6 PF15288.6 KFP20782.1 - 9.6 6.1 11.1 33 4.4 0.2 3.1 2 0 0 2 2 2 0 Zinc knuckle GSHPx PF00255.19 KFP20783.1 - 4.4e-36 122.7 0.1 6.2e-36 122.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFP20783.1 - 7.9e-06 25.8 0.0 5.1e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family TPPK_C PF12555.8 KFP20783.1 - 0.043 13.9 0.7 1.4 9.0 0.3 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Redoxin PF08534.10 KFP20783.1 - 0.1 12.3 0.0 0.58 9.9 0.0 2.0 1 1 0 1 1 1 0 Redoxin Sel1 PF08238.12 KFP20784.1 - 3e-15 56.3 0.0 2.9e-06 27.7 0.0 3.4 3 0 0 3 3 3 3 Sel1 repeat LRR_4 PF12799.7 KFP20785.1 - 4.6e-05 23.7 10.2 0.015 15.7 0.3 4.0 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) BAF250_C PF12031.8 KFP20785.1 - 0.0025 17.1 2.7 0.0029 17.0 1.2 1.8 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa DNA_alkylation PF08713.11 KFP20785.1 - 0.016 14.9 1.7 4.6 6.9 0.1 2.6 3 0 0 3 3 3 0 DNA alkylation repair enzyme DUF3361 PF11841.8 KFP20785.1 - 0.067 13.1 12.6 0.11 12.5 0.7 4.5 3 1 0 4 4 4 0 Domain of unknown function (DUF3361) His_kinase PF06580.13 KFP20785.1 - 0.15 12.4 1.5 0.32 11.3 0.4 2.1 2 0 0 2 2 2 0 Histidine kinase LRR_8 PF13855.6 KFP20785.1 - 0.38 10.6 5.3 4.4 7.1 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat Arm PF00514.23 KFP20785.1 - 1.5 9.0 7.9 97 3.2 0.1 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat ECH_1 PF00378.20 KFP20786.1 - 1.2e-50 172.2 0.1 1.3e-50 172.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFP20786.1 - 5.8e-26 91.8 0.3 2.2e-25 89.9 0.3 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase SCP2 PF02036.17 KFP20787.1 - 1.8e-29 102.2 1.0 4e-29 101.1 1.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_N PF00108.23 KFP20787.1 - 9.2e-21 74.4 0.0 3.2e-19 69.3 0.0 2.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP20787.1 - 1.5e-10 40.8 0.0 6.1e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP20787.1 - 1.7e-06 27.8 0.3 0.0023 17.6 0.2 3.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Alkyl_sulf_C PF14864.6 KFP20787.1 - 6.7e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFP20787.1 - 0.00018 21.9 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain SpoVAD PF07451.11 KFP20787.1 - 0.00026 19.8 0.2 0.02 13.6 0.0 2.4 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KFP20787.1 - 0.00057 19.7 0.2 0.0084 15.9 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KFP20787.1 - 0.046 13.8 0.1 0.24 11.4 0.0 2.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DSBA PF01323.20 KFP20787.1 - 0.054 13.3 0.1 0.23 11.2 0.0 2.1 3 0 0 3 3 3 0 DSBA-like thioredoxin domain LRR_8 PF13855.6 KFP20788.1 - 9.2e-72 236.7 59.4 1.2e-15 57.0 3.2 9.8 7 5 2 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFP20788.1 - 1.1e-44 149.7 67.3 1.3e-07 31.8 0.7 11.9 5 3 8 14 14 14 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP20788.1 - 1.7e-23 83.0 4.8 6.1e-07 29.5 0.1 5.2 2 1 4 6 6 6 6 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP20788.1 - 6e-20 68.7 46.3 0.31 11.7 0.4 15.5 14 3 0 14 14 14 7 Leucine Rich Repeat LRR_9 PF14580.6 KFP20788.1 - 4.1e-15 55.7 25.0 0.0057 16.2 1.1 6.7 1 1 6 7 7 7 6 Leucine-rich repeat LRR_6 PF13516.6 KFP20788.1 - 1.2e-11 43.7 42.8 0.71 10.1 0.5 13.3 14 0 0 14 14 14 5 Leucine Rich repeat FNIP PF05725.12 KFP20788.1 - 0.0019 18.3 17.6 7.4 6.8 0.2 7.6 4 2 2 6 6 6 2 FNIP Repeat LRRNT PF01462.18 KFP20788.1 - 0.65 9.7 5.1 29 4.5 0.1 4.3 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain SDF PF00375.18 KFP20789.1 - 2.4e-125 418.6 27.9 2.8e-125 418.4 27.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2417 PF10329.9 KFP20789.1 - 0.085 12.3 0.9 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Carn_acyltransf PF00755.20 KFP20790.1 - 9.7e-196 651.9 0.0 1.1e-195 651.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF866 PF05907.13 KFP20791.1 - 2.8e-36 124.8 0.2 2.2e-34 118.6 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Mago_nashi PF02792.14 KFP20792.1 - 4.3e-47 159.8 0.0 4.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Ldl_recept_a PF00057.18 KFP20793.1 - 7.4e-80 262.9 144.6 2.5e-13 50.0 10.7 8.0 8 0 0 8 8 7 7 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 KFP20793.1 - 7.2e-60 199.2 8.0 2.8e-15 56.5 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.6 KFP20793.1 - 1.3e-16 60.6 36.9 4.8e-09 36.4 8.0 6.0 7 0 0 7 7 3 3 Coagulation Factor Xa inhibitory site SGL PF08450.12 KFP20793.1 - 1.3e-06 28.2 0.7 0.018 14.6 0.0 2.7 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region EGF_CA PF07645.15 KFP20793.1 - 3.6e-06 27.1 11.3 3.6e-06 27.1 11.3 10.5 5 2 3 8 8 4 2 Calcium-binding EGF domain cEGF PF12662.7 KFP20793.1 - 2.2e-05 24.2 1.6 2.2e-05 24.2 1.6 5.5 4 0 0 4 4 3 2 Complement Clr-like EGF-like EGF PF00008.27 KFP20793.1 - 5.7e-05 23.3 19.7 0.00014 22.1 4.7 9.5 9 0 0 9 9 9 2 EGF-like domain SKG6 PF08693.10 KFP20793.1 - 0.00074 18.9 1.8 0.0017 17.7 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NHL PF01436.21 KFP20793.1 - 0.019 15.0 1.2 4 7.6 0.0 4.9 7 0 0 7 7 6 0 NHL repeat TMEM154 PF15102.6 KFP20793.1 - 0.025 14.5 5.0 0.15 11.9 5.0 2.1 1 1 0 1 1 1 0 TMEM154 protein family Arylesterase PF01731.20 KFP20793.1 - 0.035 14.3 0.0 7.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Arylesterase Polyhedrin PF00738.18 KFP20793.1 - 0.075 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Polyhedrin PAP_PilO PF06864.12 KFP20793.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) zf-C2H2 PF00096.26 KFP20794.1 - 6.7e-16 57.8 29.1 0.00098 19.5 0.6 6.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP20794.1 - 1.9e-10 40.7 22.0 4.9e-05 23.6 0.8 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP20794.1 - 1.7e-07 31.5 25.7 0.005 17.6 0.2 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger FOXP-CC PF16159.5 KFP20794.1 - 3.9e-06 27.4 18.4 0.013 16.1 0.2 5.6 1 1 4 5 5 5 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFP20794.1 - 0.0021 18.3 12.4 0.11 12.8 2.2 4.5 1 1 2 4 4 4 4 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFP20794.1 - 0.082 13.0 10.5 12 5.9 0.1 4.6 1 1 3 4 4 4 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFP20794.1 - 0.087 12.9 3.0 1.6 8.8 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP20794.1 - 0.093 13.0 6.6 14 6.1 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP20794.1 - 0.52 10.8 7.0 3.2 8.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KFP20794.1 - 2.1 8.2 11.3 28 4.6 0.1 4.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Ndc1_Nup PF09531.10 KFP20795.1 - 1.1e-124 417.5 9.3 1.2e-124 417.3 9.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup GP41 PF00517.17 KFP20795.1 - 0.47 10.3 2.9 0.95 9.3 2.9 1.4 1 0 0 1 1 1 0 Retroviral envelope protein Yip1 PF04893.17 KFP20796.1 - 2e-20 73.2 12.8 2.8e-20 72.7 12.8 1.3 1 0 0 1 1 1 1 Yip1 domain T4_deiodinase PF00837.17 KFP20797.1 - 5.3e-26 91.4 0.0 5.8e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase F5_F8_type_C PF00754.25 KFP20798.1 - 0.052 13.7 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 F5/8 type C domain LRR_6 PF13516.6 KFP20799.1 - 1.6e-07 30.8 9.4 0.053 13.6 0.2 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KFP20799.1 - 0.00015 22.0 5.2 0.0093 16.4 1.0 3.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP20799.1 - 0.00055 19.6 4.3 0.0029 17.3 0.1 3.0 2 1 0 2 2 2 1 Leucine rich repeat Ldl_recept_a PF00057.18 KFP20800.1 - 1.2e-10 41.4 27.9 5.9e-05 23.2 5.5 3.4 3 1 0 3 3 3 3 Low-density lipoprotein receptor domain class A BSMAP PF12280.8 KFP20801.1 - 4e-71 239.2 0.4 5.1e-71 238.8 0.4 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein Med26 PF08711.11 KFP20802.1 - 3.4e-11 43.0 0.3 3.4e-11 43.0 0.3 2.7 4 0 0 4 4 4 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 KFP20802.1 - 3.7e-08 33.8 0.5 2.1e-07 31.4 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TssR PF17643.1 KFP20802.1 - 0.051 11.5 0.0 0.059 11.3 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssR NAD_binding_1 PF00175.21 KFP20803.1 - 9.6e-14 52.0 0.0 4.3e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFP20803.1 - 1.4e-12 47.8 0.0 2.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Oxidored-like PF09791.9 KFP20803.1 - 3.7e-12 45.7 2.0 6e-11 41.8 3.2 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.12 KFP20803.1 - 4.7e-05 23.6 0.2 0.0054 16.9 0.0 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain TrbC_Ftype PF09673.10 KFP20803.1 - 0.0028 17.7 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein DUF5522 PF17653.1 KFP20803.1 - 0.57 10.2 7.7 0.16 12.0 4.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5522) PDCD9 PF07147.12 KFP20804.1 - 1.3e-11 44.4 0.1 1.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S30 (PDCD9) Thi4 PF01946.17 KFP20804.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SSDP PF04503.13 KFP20805.1 - 4.7e-72 243.7 83.5 6.2e-56 190.8 58.3 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP Ras PF00071.22 KFP20807.1 - 7.8e-52 175.1 0.2 8.8e-52 175.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20807.1 - 3e-21 75.9 0.0 4.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP20807.1 - 4.3e-10 39.3 0.0 5.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP20807.1 - 5.6e-09 36.1 0.1 5.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFP20807.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP20807.1 - 0.0001 21.9 0.0 0.00037 20.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP20807.1 - 0.00043 20.3 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFP20807.1 - 0.00066 19.1 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 KFP20807.1 - 0.0029 17.2 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KFP20807.1 - 0.0063 15.8 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 2 Septin FeoB_N PF02421.18 KFP20807.1 - 0.039 13.5 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B FERM_C PF09380.10 KFP20808.1 - 1e-21 77.1 0.0 1.8e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 KFP20808.1 - 2.3e-14 53.2 12.0 5.9e-14 51.9 12.0 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFP20808.1 - 6.3e-14 51.7 0.2 2.4e-13 49.8 0.1 2.0 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KFP20808.1 - 1.5e-13 51.2 0.9 4.2e-13 49.7 0.3 2.1 2 1 0 2 2 2 1 FERM central domain Y_phosphatase PF00102.27 KFP20809.1 - 2.2e-79 266.3 0.5 3.5e-79 265.7 0.5 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.10 KFP20809.1 - 6.6e-27 93.7 0.3 1.6e-26 92.5 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KFP20809.1 - 1.4e-24 86.8 1.2 2.5e-24 86.0 0.4 1.9 2 0 0 2 2 2 1 FERM central domain PDZ PF00595.24 KFP20809.1 - 6.8e-20 71.2 0.0 1.7e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain FERM_N PF09379.10 KFP20809.1 - 6.2e-19 67.7 0.0 3.9e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.11 KFP20809.1 - 3.1e-14 52.8 0.9 3.1e-14 52.8 0.9 2.1 2 0 0 2 2 2 1 FERM adjacent (FA) PDZ_6 PF17820.1 KFP20809.1 - 0.00026 20.8 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DSPc PF00782.20 KFP20809.1 - 0.00037 20.3 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP20809.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFP20809.1 - 0.00082 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Ras PF00071.22 KFP20811.1 - 2.7e-53 179.9 0.0 3.2e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP20811.1 - 3e-20 72.6 0.0 4.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFP20811.1 - 4.1e-07 29.7 0.1 1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KFP20811.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP20811.1 - 3.2e-05 23.9 0.6 0.028 14.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP20811.1 - 0.0024 18.0 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFP20811.1 - 0.0048 16.7 0.1 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFP20811.1 - 0.072 13.5 0.1 0.12 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KFP20811.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 KFP20811.1 - 0.12 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region F5_F8_type_C PF00754.25 KFP20815.1 - 2.8e-16 59.8 1.5 3.1e-16 59.7 1.5 1.0 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_2 PF02210.24 KFP20816.1 - 4.4e-62 208.3 0.7 2.6e-22 79.8 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 KFP20816.1 - 3.2e-47 160.0 0.0 4e-19 69.1 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.6 KFP20816.1 - 1.2e-10 41.7 0.1 0.00031 20.9 0.0 3.4 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KFP20816.1 - 1.3e-08 35.0 32.6 7.7e-05 22.9 9.1 3.6 3 0 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 KFP20816.1 - 0.012 15.9 12.8 0.012 15.9 12.8 3.7 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 KFP20816.1 - 5.7 7.7 31.9 0.033 14.8 8.1 4.2 4 0 0 4 4 4 0 Human growth factor-like EGF Consortin_C PF15281.6 KFP20820.1 - 8.6e-53 177.2 0.0 3.2e-52 175.3 0.0 2.1 1 0 0 1 1 1 1 Consortin C-terminus TPR_7 PF13176.6 KFP20820.1 - 0.091 12.8 0.2 0.55 10.4 0.2 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat RrnaAD PF00398.20 KFP20821.1 - 2.6e-11 43.1 0.0 3.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase APOBEC_N PF08210.11 KFP20821.1 - 0.037 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain SET PF00856.28 KFP20822.1 - 3.5e-13 50.3 0.1 9.6e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.6 KFP20822.1 - 0.0072 16.6 0.0 0.027 14.7 0.0 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat EF-hand_6 PF13405.6 KFP20823.1 - 1.8e-11 43.0 0.0 0.00025 20.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFP20823.1 - 2.5e-09 37.4 0.1 0.00055 20.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KFP20823.1 - 1e-07 32.1 0.0 7.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP20823.1 - 1.3e-06 27.6 0.2 0.057 13.0 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KFP20823.1 - 0.0016 18.3 0.0 0.0077 16.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 KFP20823.1 - 0.0084 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 KFP20823.1 - 0.1 12.1 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.6 KFP20824.1 - 7.6e-28 97.5 0.3 1.5e-27 96.5 0.1 1.5 2 0 0 2 2 2 1 AAA domain SPRY PF00622.28 KFP20824.1 - 2.1e-14 53.7 0.2 2.1e-14 53.7 0.2 2.0 2 0 0 2 2 2 1 SPRY domain SRP54 PF00448.22 KFP20824.1 - 0.022 14.4 0.2 0.038 13.6 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KFP20824.1 - 0.11 11.7 0.2 0.28 10.4 0.2 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KFP20824.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3767 PF12597.8 KFP20825.1 - 6.4e-14 51.6 0.1 7.8e-14 51.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Peptidase_C97 PF05903.14 KFP20826.1 - 5.3e-39 133.5 0.0 6.9e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KFP20826.1 - 0.098 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Adenylsucc_synt PF00709.21 KFP20827.1 - 1.5e-159 531.5 0.0 1.6e-159 531.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spore_YpjB PF09577.10 KFP20827.1 - 0.055 13.3 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF5530 PF17670.1 KFP20828.1 - 1.8e-21 76.4 0.0 2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5530) BTB PF00651.31 KFP20829.1 - 2.2e-27 95.5 1.3 3.8e-27 94.7 1.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP20829.1 - 1.8e-15 56.3 29.8 0.00031 21.3 3.1 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP20829.1 - 7.7e-15 54.6 26.8 1.1e-07 31.9 1.9 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP20829.1 - 1.3e-13 50.6 34.7 0.00079 19.8 2.4 5.0 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFP20829.1 - 3.6e-05 23.9 15.6 0.0037 17.5 0.0 4.7 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP20829.1 - 0.0011 18.9 22.3 0.35 10.9 2.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KFP20829.1 - 0.0027 18.0 0.1 0.0027 18.0 0.1 5.3 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP20829.1 - 0.012 15.3 19.9 0.28 11.0 0.4 4.6 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 KFP20829.1 - 0.018 15.5 2.0 0.018 15.5 2.0 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KFP20829.1 - 0.022 14.5 6.3 0.54 10.1 0.2 3.5 2 1 1 3 3 3 0 GAGA factor CpXC PF14353.6 KFP20829.1 - 0.027 14.5 6.2 0.37 10.9 0.5 2.7 2 0 0 2 2 2 0 CpXC protein zf_C2H2_10 PF18414.1 KFP20829.1 - 0.1 12.2 1.4 0.34 10.5 1.4 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger zf_UBZ PF18439.1 KFP20829.1 - 0.16 11.6 7.0 3.6 7.2 0.2 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KFP20829.1 - 0.3 11.2 7.3 0.36 11.0 0.9 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf-LYAR PF08790.11 KFP20829.1 - 0.32 11.0 9.6 0.63 10.0 0.4 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger PknG_rubred PF16919.5 KFP20829.1 - 2.1 8.5 5.6 0.46 10.7 0.6 2.5 2 1 2 4 4 4 0 Protein kinase G rubredoxin domain zinc_ribbon_15 PF17032.5 KFP20829.1 - 3 8.7 9.8 1.4e+02 3.3 6.4 3.5 2 1 1 3 3 3 0 zinc-ribbon family FYVE PF01363.21 KFP20829.1 - 5.5 7.2 20.0 12 6.1 5.1 4.5 3 1 2 5 5 5 0 FYVE zinc finger XPA_N PF01286.18 KFP20829.1 - 8.1 6.6 9.4 26 4.9 0.1 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Pkinase PF00069.25 KFP20830.1 - 2.9e-77 259.6 0.1 6.4e-77 258.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20830.1 - 2.3e-36 125.4 0.0 3.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KFP20830.1 - 1.1e-10 42.0 0.3 3.1e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 KFP20830.1 - 1.3e-09 38.6 2.7 2.7e-09 37.6 2.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP20830.1 - 1.3e-08 34.5 0.0 3.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KFP20830.1 - 0.0091 15.6 0.4 0.97 9.0 0.1 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFP20830.1 - 0.19 11.6 0.4 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CCCAP PF15964.5 KFP20831.1 - 0 1075.2 86.1 0 1075.1 86.1 1.0 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family SlyX PF04102.12 KFP20831.1 - 0.014 16.0 4.7 0.014 16.0 4.7 9.6 4 1 4 9 9 9 0 SlyX DUF3618 PF12277.8 KFP20831.1 - 0.071 13.4 4.4 2.5 8.4 1.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) MbeD_MobD PF04899.12 KFP20831.1 - 0.14 12.3 0.3 0.14 12.3 0.3 5.8 3 2 0 4 4 4 0 MbeD/MobD like CENP-F_leu_zip PF10473.9 KFP20831.1 - 5.5 7.0 107.5 0.065 13.3 17.8 7.5 3 1 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CEP170_C PF15308.6 KFP20832.1 - 1.1e-261 870.3 62.3 1.1e-261 870.3 62.3 3.8 4 0 0 4 4 4 1 CEP170 C-terminus FHA PF00498.26 KFP20832.1 - 1.3e-15 57.5 0.1 4.6e-15 55.7 0.1 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFP20832.1 - 2.3e-09 37.5 0.2 1.4e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF4254 PF14063.6 KFP20832.1 - 0.0039 17.0 0.8 0.019 14.8 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4254) Trns_repr_metal PF02583.17 KFP20832.1 - 0.56 10.6 2.6 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor RVT_1 PF00078.27 KFP20833.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLDc_3 PF13918.6 KFP20835.1 - 2e-82 275.2 1.0 3.9e-82 274.2 1.0 1.5 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 KFP20835.1 - 2.5e-12 46.8 0.1 1.2e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFP20835.1 - 1.5e-08 34.5 1.2 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif FAM83 PF07894.12 KFP20835.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 FAM83 A-H Atg8 PF02991.16 KFP20836.1 - 2.5e-39 133.7 0.3 2.8e-39 133.5 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFP20836.1 - 5.3e-06 26.8 0.1 6.4e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 XPG_I PF00867.18 KFP20837.1 - 2.1e-24 85.7 0.1 7.2e-24 84.0 0.1 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFP20837.1 - 2.6e-16 59.9 0.0 6.4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFP20837.1 - 0.0003 20.4 0.0 0.00072 19.1 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing WD40 PF00400.32 KFP20838.1 - 1.6e-08 35.0 0.1 0.07 14.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KFP20838.1 - 0.044 12.5 0.0 4 6.1 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KFP20838.1 - 0.05 13.9 0.2 1.6 9.1 0.0 2.6 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HTH_10 PF04967.12 KFP20838.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Mannosyl_trans PF05007.13 KFP20840.1 - 4.3e-88 295.5 25.6 2.2e-69 234.2 22.5 2.0 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KFP20840.1 - 1.3e-06 27.7 0.1 1.3e-06 27.7 0.1 2.8 1 1 2 3 3 3 2 GPI transamidase subunit PIG-U UL42 PF17638.2 KFP20840.1 - 0.44 10.5 1.7 0.8 9.7 0.1 2.1 2 0 0 2 2 2 0 HCMV UL42 RGS_DHEX PF18148.1 KFP20841.1 - 6.4e-51 170.6 1.6 3e-50 168.4 1.6 2.2 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP20841.1 - 3e-35 121.1 1.3 1.3e-34 119.0 0.0 2.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 KFP20841.1 - 1.3e-18 66.8 0.0 7.2e-18 64.4 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFP20841.1 - 3.7e-15 55.7 0.1 1.5e-14 53.7 0.1 2.0 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 KFP20841.1 - 0.089 12.5 0.0 0.089 12.5 0.0 2.1 3 0 0 3 3 3 0 Regulator of G protein signalling-like domain DAN PF03045.15 KFP20842.1 - 5.2e-41 139.2 10.8 7.1e-41 138.8 10.8 1.1 1 0 0 1 1 1 1 DAN domain Sfi1_C PF10638.9 KFP20842.1 - 0.091 13.5 0.9 0.15 12.9 0.2 1.7 2 0 0 2 2 2 0 Spindle body associated protein C-terminus NTP_transf_9 PF04248.12 KFP20842.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) FH2 PF02181.23 KFP20843.1 - 0.0086 15.2 1.3 0.0093 15.1 0.2 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain FH2 PF02181.23 KFP20844.1 - 6.1e-81 272.4 6.9 6.9e-81 272.2 6.9 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH1 PF06346.12 KFP20844.1 - 1.2e-05 25.1 103.7 0.00012 21.9 57.8 2.2 1 1 1 2 2 2 2 Formin Homology Region 1 IFN-gamma PF00714.17 KFP20844.1 - 0.075 12.9 0.2 0.075 12.9 0.2 2.6 2 1 0 2 2 2 0 Interferon gamma 7tm_1 PF00001.21 KFP20845.1 - 1.7e-78 263.6 1.3 2.3e-78 263.1 1.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP20845.1 - 6.6e-09 35.5 6.6 6.6e-09 35.5 6.6 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP20845.1 - 1.5e-06 28.1 12.2 1.5e-06 28.1 12.2 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP20845.1 - 7.6e-06 25.9 11.7 1.9e-05 24.5 3.8 2.3 2 1 0 2 2 2 2 Olfactory receptor CitMHS PF03600.16 KFP20845.1 - 6.2 5.9 10.1 1.3e+02 1.6 13.1 1.3 1 1 0 1 1 1 0 Citrate transporter RVT_1 PF00078.27 KFP20846.1 - 0.0016 18.0 0.0 0.0031 17.0 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HlyIII PF03006.20 KFP20849.1 - 1.2e-36 126.5 18.5 1.5e-36 126.3 18.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF2070 PF09843.9 KFP20849.1 - 0.37 9.0 5.0 0.48 8.7 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1275 PF06912.11 KFP20849.1 - 0.51 10.2 6.5 0.19 11.7 1.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1275) BMP2K_C PF15282.6 KFP20850.1 - 3.3e-120 400.7 12.1 3.3e-120 400.7 12.1 2.7 2 1 1 3 3 3 2 BMP-2-inducible protein kinase C-terminus HpuA PF16960.5 KFP20850.1 - 0.076 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter DivIC PF04977.15 KFP20850.1 - 0.079 12.7 3.9 0.21 11.4 3.9 1.7 1 0 0 1 1 1 0 Septum formation initiator FAM76 PF16046.5 KFP20850.1 - 9.8 5.4 13.2 0.65 9.3 6.7 1.9 2 0 0 2 2 2 0 FAM76 protein Pkinase PF00069.25 KFP20851.1 - 3.1e-42 144.8 1.0 5.6e-42 143.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20851.1 - 4.7e-24 85.1 0.9 7e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP20851.1 - 3.7e-08 33.0 3.1 7.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP20851.1 - 0.0011 17.9 1.5 0.0057 15.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP20851.1 - 0.0066 15.4 0.0 0.0066 15.4 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFP20851.1 - 0.02 14.8 0.1 0.02 14.8 0.1 2.8 2 2 1 3 3 3 0 Phosphotransferase enzyme family NTF2 PF02136.20 KFP20852.1 - 3e-33 115.0 0.1 5.1e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KFP20852.1 - 4.2e-14 52.1 0.1 8.5e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP20852.1 - 8.5e-06 25.8 0.0 2.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif Uso1_p115_head PF04869.14 KFP20853.1 - 8.3e-62 209.1 0.0 8.3e-62 209.1 0.0 2.5 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 KFP20853.1 - 1.2e-28 98.7 1.4 1.2e-28 98.7 1.4 2.8 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 KFP20853.1 - 1.5e-12 48.0 16.3 1.5e-12 48.0 16.3 4.6 3 1 1 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 KFP20853.1 - 0.0052 17.0 14.1 0.0052 17.0 14.1 4.9 3 1 0 4 4 4 2 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 KFP20853.1 - 0.061 12.7 24.0 0.022 14.1 3.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 KFP20853.1 - 0.12 12.2 45.1 0.16 11.8 14.4 3.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF2937 PF11157.8 KFP20853.1 - 3.5 7.3 6.1 14 5.3 2.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) EGF PF00008.27 KFP20854.1 - 0.00094 19.4 3.1 0.0016 18.7 3.1 1.4 1 0 0 1 1 1 1 EGF-like domain Ycf70 PF17382.2 KFP20854.1 - 0.0012 19.2 0.8 0.0071 16.7 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized Ycf70-like PRIMA1 PF16101.5 KFP20854.1 - 0.02 14.9 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FtsL PF04999.13 KFP20854.1 - 0.029 14.3 0.2 0.047 13.7 0.2 1.3 1 0 0 1 1 1 0 Cell division protein FtsL TMEM154 PF15102.6 KFP20854.1 - 0.032 14.2 1.0 0.054 13.4 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF3377 PF11857.8 KFP20854.1 - 0.035 14.0 0.3 0.079 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ECSCR PF15820.5 KFP20854.1 - 0.041 13.7 0.4 0.041 13.7 0.4 1.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Protocadherin PF08374.11 KFP20854.1 - 0.37 10.7 3.1 0.77 9.7 0.1 2.1 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.6 KFP20854.1 - 3.2 8.7 5.2 0.67 10.9 0.2 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EGF PF00008.27 KFP20855.1 - 0.00042 20.6 4.3 0.00067 19.9 4.3 1.4 1 0 0 1 1 1 1 EGF-like domain PAP_PilO PF06864.12 KFP20855.1 - 0.011 14.6 0.1 0.013 14.3 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2207 PF09972.9 KFP20855.1 - 0.12 11.1 0.2 0.14 10.9 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Vpu PF00558.19 KFP20855.1 - 0.17 11.6 0.3 0.26 11.1 0.3 1.2 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.13 KFP20855.1 - 0.18 12.2 2.8 0.43 11.0 2.8 1.7 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.27 KFP20856.1 - 0.042 14.2 3.4 0.086 13.2 3.4 1.6 1 0 0 1 1 1 0 EGF-like domain DUF4514 PF14986.6 KFP20856.1 - 0.071 13.1 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) SKG6 PF08693.10 KFP20856.1 - 1.7 8.1 4.5 3.8 7.0 4.5 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain THF_DHG_CYH_C PF02882.19 KFP20857.1 - 2.3e-50 170.0 4.8 2e-49 167.0 4.8 2.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFP20857.1 - 1.8e-38 131.3 0.1 2.7e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 KFP20857.1 - 0.02 14.2 0.4 0.033 13.5 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Brix PF04427.18 KFP20858.1 - 1.6e-45 155.6 0.1 2.5e-45 155.0 0.1 1.3 1 0 0 1 1 1 1 Brix domain TFIIIC_sub6 PF10419.9 KFP20859.1 - 1.5e-17 63.2 0.1 2.7e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain SAM_decarbox PF01536.16 KFP20860.1 - 7.8e-112 373.8 2.7 8.8e-112 373.6 2.7 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.25 KFP20862.1 - 4.1e-52 177.1 0.0 4.9e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20862.1 - 3.6e-19 69.1 0.0 5.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP20862.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KFP20862.1 - 0.058 12.7 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 KFP20864.1 - 1.9e-24 86.3 50.0 6.7e-22 77.9 28.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP20864.1 - 4.6e-24 85.1 25.4 6.2e-24 84.7 25.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.24 KFP20865.1 - 3.4e-34 119.0 0.0 3.8e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KFP20865.1 - 0.0035 16.9 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 KFP20865.1 - 0.0069 15.5 0.0 0.025 13.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFP20865.1 - 0.011 15.0 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KFP20865.1 - 0.024 14.2 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KFP20865.1 - 0.029 14.9 0.1 0.36 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFP20865.1 - 0.041 14.1 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KFP20865.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KFP20865.1 - 0.17 11.1 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_22 PF13383.6 KFP20866.1 - 6.4e-12 45.6 0.4 7.3e-12 45.4 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KFP20866.1 - 1.7e-06 28.2 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain WD40 PF00400.32 KFP20867.1 - 2.7e-37 126.1 11.9 2e-06 28.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP20867.1 - 2.2e-11 43.9 0.1 0.008 16.5 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP20867.1 - 0.0044 16.9 0.4 2.1 8.2 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KFP20867.1 - 0.045 13.3 0.0 0.15 11.6 0.0 1.8 2 1 1 3 3 3 0 PQQ-like domain 7tm_1 PF00001.21 KFP20869.1 - 2e-29 102.7 13.8 2.6e-29 102.4 13.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP20869.1 - 0.00084 19.2 14.3 0.0086 15.8 14.3 2.5 1 1 0 1 1 1 1 Olfactory receptor Syja_N PF02383.18 KFP20871.1 - 2e-73 247.5 0.0 3.8e-73 246.6 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain ADK PF00406.22 KFP20872.1 - 1.4e-20 73.9 0.3 1.1e-18 67.8 0.1 2.5 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 KFP20872.1 - 8.3e-10 39.2 1.9 1e-07 32.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KFP20872.1 - 8e-06 26.3 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFP20872.1 - 2.4e-05 24.9 2.1 0.0089 16.6 1.3 3.1 2 1 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 KFP20872.1 - 3.1e-05 24.4 0.3 0.058 13.7 0.1 2.6 2 1 0 2 2 2 2 Hydin Adenylate kinase-like domain NACHT PF05729.12 KFP20872.1 - 0.00039 20.4 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KTI12 PF08433.10 KFP20872.1 - 0.0014 18.2 1.9 0.43 10.0 0.0 3.2 3 0 0 3 3 3 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 KFP20872.1 - 0.0019 18.7 1.2 0.32 11.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 KFP20872.1 - 0.0033 17.8 0.1 0.41 11.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFP20872.1 - 0.0037 17.3 0.1 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFP20872.1 - 0.0057 16.9 0.1 0.47 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFP20872.1 - 0.01 15.6 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain FAP206 PF12018.8 KFP20872.1 - 0.018 14.6 2.4 0.02 14.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function Mg_chelatase PF01078.21 KFP20872.1 - 0.018 14.4 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Herpes_Helicase PF02689.14 KFP20872.1 - 0.034 12.1 0.0 0.052 11.5 0.0 1.2 1 0 0 1 1 1 0 Helicase AAA_33 PF13671.6 KFP20872.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFP20872.1 - 0.11 12.9 0.2 9.6 6.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase PBP_sp32 PF07222.12 KFP20872.1 - 0.13 11.7 2.9 0.2 11.1 2.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SKI PF01202.22 KFP20872.1 - 0.14 12.3 2.6 0.45 10.6 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase AAA_24 PF13479.6 KFP20872.1 - 0.17 11.6 1.3 8.1 6.1 0.0 2.9 3 1 0 3 3 3 0 AAA domain DUF4820 PF16091.5 KFP20872.1 - 0.18 11.2 1.7 0.27 10.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AAA_30 PF13604.6 KFP20872.1 - 0.18 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFP20872.1 - 1.1 9.5 4.4 6.1 7.1 0.0 3.2 3 1 1 4 4 4 0 AAA domain ADK PF00406.22 KFP20873.1 - 4.1e-13 49.7 0.1 1.1e-08 35.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFP20873.1 - 2.7e-12 47.3 0.0 3.3e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KFP20873.1 - 1.9e-08 34.9 0.0 7.4e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain FAP206 PF12018.8 KFP20873.1 - 2.6e-05 23.9 0.3 6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function AAA_28 PF13521.6 KFP20873.1 - 6.8e-05 23.2 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain YHS PF04945.13 KFP20873.1 - 0.00046 20.2 4.7 0.0016 18.5 2.1 2.6 1 1 1 2 2 2 1 YHS domain AAA PF00004.29 KFP20873.1 - 0.00056 20.3 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFP20873.1 - 0.0037 17.4 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KFP20873.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFP20873.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KFP20873.1 - 0.017 15.0 0.0 0.52 10.1 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KFP20873.1 - 0.022 14.7 0.0 0.094 12.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SKI PF01202.22 KFP20873.1 - 0.023 14.8 0.0 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase G-alpha PF00503.20 KFP20873.1 - 0.043 13.0 0.0 0.056 12.6 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 KFP20873.1 - 0.064 13.8 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP20873.1 - 0.066 13.5 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFP20873.1 - 0.09 12.8 1.7 0.32 11.0 0.2 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFP20873.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 KFP20873.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFP20873.1 - 0.18 12.2 0.3 0.97 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ADK PF00406.22 KFP20874.1 - 1.6e-17 64.0 0.0 2.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFP20874.1 - 9.5e-13 48.7 0.0 2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain FAP206 PF12018.8 KFP20874.1 - 1.2e-11 44.7 0.7 1.1e-05 25.1 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function YHS PF04945.13 KFP20874.1 - 1.9e-10 40.7 0.7 0.0034 17.4 0.1 3.6 3 0 0 3 3 3 3 YHS domain AAA_18 PF13238.6 KFP20874.1 - 0.00026 21.5 0.2 0.0044 17.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KFP20874.1 - 0.0072 16.1 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFP20874.1 - 0.0076 16.5 0.0 0.066 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFP20874.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KFP20874.1 - 0.055 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KFP20874.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase G-alpha PF00503.20 KFP20874.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Hydin_ADK PF17213.3 KFP20874.1 - 0.097 12.9 0.1 0.86 9.9 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Cytochrom_B558a PF05038.13 KFP20874.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit AAA_22 PF13401.6 KFP20874.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pro_isomerase PF00160.21 KFP20875.1 - 5.8e-41 140.4 0.0 7.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4303 PF14136.6 KFP20875.1 - 0.02 14.6 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) MGC-24 PF05283.11 KFP20876.1 - 4.9e-33 114.5 9.2 4.9e-33 114.5 9.2 1.9 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adeno_E3_CR2 PF02439.15 KFP20876.1 - 0.012 15.3 0.4 0.4 10.5 0.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF4366 PF14283.6 KFP20876.1 - 0.025 14.6 0.5 0.1 12.6 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 KFP20876.1 - 0.18 11.7 0.3 0.22 11.4 0.3 1.1 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 KFP20876.1 - 0.64 9.4 3.3 0.88 8.9 3.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.9 KFP20876.1 - 2.1 7.4 13.4 2.4 7.3 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5585 PF17823.1 KFP20876.1 - 6.7 5.5 36.4 8.2 5.3 36.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) PA26 PF04636.13 KFP20879.1 - 6.2e-210 697.7 2.0 7e-210 697.5 2.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFP20879.1 - 0.00034 20.6 0.0 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Arm PF00514.23 KFP20880.1 - 4e-08 33.0 5.7 1.1 9.4 0.0 6.8 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat PUL PF08324.11 KFP20880.1 - 6e-06 25.7 1.7 3.4e-05 23.2 0.2 2.7 2 1 1 3 3 3 1 PUL domain KAP PF05804.12 KFP20880.1 - 0.00016 20.0 15.6 0.013 13.7 1.5 3.1 2 2 1 3 3 3 2 Kinesin-associated protein (KAP) Arm_2 PF04826.13 KFP20880.1 - 1.1 8.7 22.3 0.06 12.8 0.8 3.8 3 2 1 4 4 4 0 Armadillo-like GON PF08685.11 KFP20882.1 - 0.097 12.5 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 GON domain AFG1_ATPase PF03969.16 KFP20884.1 - 2.3e-113 378.8 3.7 1.2e-109 366.5 0.7 2.0 1 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KFP20884.1 - 7.5e-05 23.2 0.3 0.039 14.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 KFP20884.1 - 0.00014 22.3 0.2 0.0011 19.4 0.0 2.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP20884.1 - 0.0025 18.1 0.2 0.011 16.0 0.0 2.3 3 1 0 3 3 3 1 AAA domain UvrD-helicase PF00580.21 KFP20884.1 - 0.0032 17.0 0.1 0.024 14.2 0.1 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_14 PF13173.6 KFP20884.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFP20884.1 - 0.025 14.9 0.1 1.2 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFP20884.1 - 0.027 14.4 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFP20884.1 - 0.064 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KFP20884.1 - 0.079 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KFP20884.1 - 0.094 12.6 0.1 0.27 11.1 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mrx7 PF10906.8 KFP20884.1 - 0.12 12.6 0.2 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 MIOREX complex component 7 PX PF00787.24 KFP20885.1 - 2e-22 79.3 0.2 2.2e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.20 KFP20885.1 - 0.033 12.7 0.0 0.036 12.6 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Hormone_recep PF00104.30 KFP20886.1 - 2e-34 119.0 0.0 2.5e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP20886.1 - 6.1e-18 65.1 3.9 2.3e-17 63.2 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 KFP20886.1 - 7.4 7.0 6.7 1.4 9.3 2.6 2.0 2 1 0 2 2 2 0 C1 domain OSTMP1 PF09777.9 KFP20887.1 - 6.1e-74 248.3 9.3 6.8e-74 248.2 9.3 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.6 KFP20887.1 - 0.0012 18.7 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family TMEM52 PF14979.6 KFP20888.1 - 0.045 13.7 9.7 0.12 12.3 1.8 2.1 2 0 0 2 2 2 0 Transmembrane 52 WBP-1 PF11669.8 KFP20888.1 - 0.11 13.1 18.5 0.56 10.9 18.5 2.0 1 1 0 1 1 1 0 WW domain-binding protein 1 SecE PF00584.20 KFP20890.1 - 6.4e-17 61.2 0.1 8.1e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TPK_catalytic PF04263.16 KFP20891.1 - 1.5e-27 96.0 0.0 1.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KFP20891.1 - 8.6e-24 83.0 0.5 1.4e-23 82.4 0.5 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Peptidase_C15 PF01470.17 KFP20891.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyroglutamyl peptidase NUFIP1 PF10453.9 KFP20893.1 - 2.5e-20 72.0 7.0 7e-20 70.6 7.0 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 KFP20893.1 - 3.3e-05 24.0 3.9 9.8e-05 22.5 3.9 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding PCNP PF15473.6 KFP20893.1 - 0.0056 17.4 1.6 0.0056 17.4 1.6 2.2 3 0 0 3 3 3 1 PEST, proteolytic signal-containing nuclear protein family zf-C2H2 PF00096.26 KFP20893.1 - 0.77 10.3 6.3 0.21 12.1 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP20893.1 - 2.7 9.1 7.7 2.2 9.3 0.3 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger DUF3752 PF12572.8 KFP20894.1 - 1.8e-25 90.2 18.8 1.8e-25 90.2 18.8 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3752) DUF4065 PF13274.6 KFP20894.1 - 2.5 9.0 6.3 15 6.5 2.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4065) TFIIF_beta PF02270.15 KFP20895.1 - 8.6e-28 96.3 1.0 1.2e-27 95.8 0.2 1.6 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KFP20895.1 - 1.2e-14 55.2 0.5 6.5e-14 52.8 0.5 2.3 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus BTB_2 PF02214.22 KFP20896.1 - 2.3e-18 66.3 0.0 6.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KFP20896.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TCTP PF00838.17 KFP20897.1 - 3.5e-59 199.9 0.2 3.9e-59 199.7 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Endotoxin_N PF03945.14 KFP20897.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Mito_carr PF00153.27 KFP20898.1 - 4.9e-43 145.0 0.3 2e-19 69.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 KFP20899.1 - 9.8e-55 184.5 6.8 9.8e-55 184.5 6.8 4.1 5 0 0 5 5 5 2 Sec34-like family PP2C_C PF07830.13 KFP20899.1 - 0.049 14.1 0.6 0.48 10.9 0.1 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain CLTH PF10607.9 KFP20899.1 - 0.051 13.5 8.2 0.023 14.6 0.9 3.1 3 0 0 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain NPV_P10 PF05531.12 KFP20899.1 - 0.074 13.5 4.2 5.7 7.5 0.2 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KFP20899.1 - 3.3 7.8 16.1 4.7 7.2 4.1 5.0 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin_like PF18373.1 KFP20901.1 - 0.066 13.3 0.4 0.12 12.5 0.3 1.5 1 1 0 1 1 1 0 Spectrin like domain Chibby PF14645.6 KFP20903.1 - 1.1e-05 25.8 0.0 1.1e-05 25.8 0.0 3.5 2 1 1 3 3 3 1 Chibby family zf-RING_9 PF13901.6 KFP20907.1 - 9.1e-67 225.0 20.6 1.5e-66 224.3 20.6 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Ploopntkinase1 PF18748.1 KFP20907.1 - 0.053 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 LRR_8 PF13855.6 KFP20910.1 - 7.1e-24 83.3 10.2 2.4e-10 40.0 1.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP20910.1 - 1.9e-16 59.9 16.8 0.0011 19.4 1.7 5.5 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) CH PF00307.31 KFP20910.1 - 4.1e-11 43.0 0.0 9.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_1 PF00560.33 KFP20910.1 - 1.7e-06 27.7 16.0 1 10.2 0.8 6.7 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP20910.1 - 0.00079 19.3 10.2 1.5 9.1 0.5 5.2 5 0 0 5 5 5 2 Leucine Rich repeat CAMSAP_CH PF11971.8 KFP20910.1 - 0.0044 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain 7tm_1 PF00001.21 KFP20912.1 - 2.1e-67 227.2 14.7 3.3e-67 226.6 14.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP20912.1 - 1.5e-14 54.0 19.1 2.4e-14 53.3 19.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP20912.1 - 2.3e-07 30.9 9.2 2.3e-07 30.9 9.2 1.9 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP20912.1 - 9.7e-07 28.7 14.9 9.7e-07 28.7 14.9 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Bee_toxin PF17454.2 KFP20912.1 - 4.8 7.3 10.7 0.071 13.1 1.3 2.6 2 0 0 2 2 2 0 Honey bee toxin ATP-grasp_2 PF08442.10 KFP20916.1 - 3.5e-74 248.7 1.0 7.3e-74 247.7 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KFP20916.1 - 1.3e-26 93.3 2.6 2.1e-26 92.6 2.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFP20916.1 - 1.6e-09 37.6 0.3 4.2e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KFP20916.1 - 0.043 13.6 0.4 0.14 11.9 0.4 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain nsp7 PF08716.10 KFP20916.1 - 0.12 13.0 1.9 2.5 8.8 0.3 2.7 2 1 0 2 2 2 0 nsp7 replicase Med4 PF10018.9 KFP20917.1 - 2.2e-31 109.0 0.2 3.3e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HMMR_N PF15905.5 KFP20917.1 - 0.00011 21.8 6.5 0.00015 21.3 6.5 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Mu-like_Pro PF10123.9 KFP20917.1 - 0.0074 15.9 0.9 0.01 15.4 0.9 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein Csm1_N PF18504.1 KFP20917.1 - 0.06 13.7 5.9 0.16 12.4 5.9 1.8 1 1 0 1 1 1 0 Csm1 N-terminal domain Trans_reg_C PF00486.28 KFP20917.1 - 0.2 11.8 1.3 3.6 7.7 0.3 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal FAM76 PF16046.5 KFP20917.1 - 0.29 10.5 4.0 0.39 10.0 4.0 1.1 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 KFP20917.1 - 0.29 11.0 5.4 0.42 10.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRICHOS PF04089.14 KFP20918.1 - 3.7e-20 72.0 0.0 5.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 BRICHOS domain Antiterm PF03589.13 KFP20918.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Antitermination protein Rb_C PF08934.10 KFP20919.1 - 6.6e-82 272.7 3.3 6.6e-82 272.7 3.3 2.3 2 0 0 2 2 2 1 Rb C-terminal domain RB_A PF01858.17 KFP20919.1 - 1.1e-76 257.1 0.5 3.6e-76 255.4 0.1 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KFP20919.1 - 5.2e-31 107.4 4.8 5.2e-31 107.4 4.8 2.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KFP20919.1 - 6.3e-15 54.9 6.7 6.5e-14 51.7 2.8 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) Mre11_DNA_bind PF04152.14 KFP20919.1 - 0.1 12.9 0.3 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DUF1955 PF09205.10 KFP20919.1 - 0.82 9.4 3.2 0.49 10.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) 7tm_1 PF00001.21 KFP20920.1 - 1.5e-54 185.1 30.8 1.9e-54 184.8 30.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP20920.1 - 5.9e-05 22.8 32.1 5.9e-05 22.8 32.1 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UCMA PF17085.5 KFP20920.1 - 0.084 12.9 1.0 0.64 10.0 0.6 2.2 1 1 1 2 2 2 0 Unique cartilage matrix associated protein RCC1 PF00415.18 KFP20921.1 - 1.5e-62 208.0 25.1 3.9e-16 59.4 1.4 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP20921.1 - 6.8e-32 108.6 26.9 2.9e-11 42.9 1.2 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFP20921.1 - 3.2e-20 72.4 1.1 2.4e-17 63.2 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 KFP20921.1 - 3.1e-06 27.2 2.2 0.00034 20.7 0.3 3.1 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.6 KFP20921.1 - 0.0077 16.5 2.6 3.1 8.1 0.0 3.1 2 1 0 2 2 2 2 Putative heavy-metal chelation Phage_int_SAM_5 PF13102.6 KFP20921.1 - 0.052 13.9 1.0 0.3 11.4 0.1 2.2 1 1 1 2 2 2 0 Phage integrase SAM-like domain Hira PF07569.11 KFP20921.1 - 0.06 13.1 3.3 4.6 6.9 0.0 4.0 5 0 0 5 5 5 0 TUP1-like enhancer of split Kelch_5 PF13854.6 KFP20921.1 - 4.9 7.3 8.4 45 4.2 0.2 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 KFP20921.1 - 6.2 7.0 8.8 15 5.7 0.2 4.7 5 0 0 5 5 5 0 Kelch motif 7tm_1 PF00001.21 KFP20922.1 - 9.3e-52 175.9 27.0 1.4e-51 175.3 27.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP20922.1 - 6e-08 32.4 20.4 6e-08 32.4 20.4 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KFP20922.1 - 2.9e-07 30.4 21.7 2.9e-07 30.4 21.7 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KFP20922.1 - 2.3e-05 23.8 29.7 0.0016 17.8 29.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TAS2R PF05296.13 KFP20922.1 - 0.00043 19.5 25.8 0.00072 18.8 25.8 1.2 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) 7TM_GPCR_Sru PF10322.9 KFP20922.1 - 0.01 15.2 29.4 0.0049 16.2 26.8 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru Deltameth_res PF16020.5 KFP20922.1 - 0.53 10.2 3.0 9.9 6.1 0.0 3.0 2 0 0 2 2 2 0 Deltamethrin resistance S1FA PF04689.13 KFP20922.1 - 0.63 10.2 4.8 0.17 12.0 0.5 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA fn3 PF00041.21 KFP20923.1 - 1.7e-87 287.9 0.0 2.1e-10 40.8 0.0 9.9 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP20923.1 - 5.2e-18 65.4 10.6 0.05 14.2 0.1 9.3 8 3 1 9 9 9 6 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFP20923.1 - 4.2e-12 46.3 0.0 0.16 12.4 0.0 6.9 7 0 0 7 7 7 3 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFP20923.1 - 1.1e-05 25.7 5.2 0.22 11.9 0.1 5.8 7 0 0 7 7 7 1 Interferon-alpha/beta receptor, fibronectin type III Orf78 PF06024.12 KFP20923.1 - 0.21 11.9 0.1 0.44 10.9 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) IL6Ra-bind PF09240.10 KFP20923.1 - 0.21 12.0 3.8 11 6.5 0.3 2.7 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding dCMP_cyt_deam_1 PF00383.23 KFP20924.1 - 5.5e-19 67.9 0.6 5.2e-09 35.9 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFP20924.1 - 6.6e-12 45.3 0.5 3.1e-05 23.8 0.1 2.7 2 1 0 2 2 2 2 MafB19-like deaminase SNAD4 PF18750.1 KFP20924.1 - 0.0076 16.4 0.5 1.2 9.2 0.1 2.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFP20924.1 - 0.013 15.6 1.2 0.83 9.7 0.2 2.4 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 AID PF18767.1 KFP20924.1 - 0.09 12.8 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Activation induced deaminase APOBEC3 PF18771.1 KFP20924.1 - 0.1 12.7 0.6 13 5.9 0.1 2.7 2 0 0 2 2 2 0 APOBEC3 GerPE PF10970.8 KFP20924.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Spore germination protein GerPE Mo25 PF08569.11 KFP20925.1 - 1.3e-132 442.2 11.7 1.4e-132 442.0 11.7 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 KFP20925.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats WcbI PF18588.1 KFP20925.1 - 0.085 12.5 0.1 2.1 7.9 0.0 2.5 2 1 1 3 3 3 0 Polysaccharide biosynthesis enzyme WcbI JmjN PF02375.17 KFP20925.1 - 0.49 10.4 2.3 3.1 7.8 0.2 3.0 3 0 0 3 3 3 0 jmjN domain SET PF00856.28 KFP20926.1 - 3.7e-26 92.5 0.3 1.9e-25 90.2 0.1 2.1 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFP20926.1 - 3.1e-13 50.3 11.0 3.1e-13 50.3 11.0 3.3 3 1 0 3 3 3 1 Pre-SET motif MBD PF01429.19 KFP20926.1 - 2.2e-08 33.7 0.0 6.2e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain zf-HC5HC2H PF13771.6 KFP20927.1 - 1.4e-14 54.1 2.0 1.4e-14 54.1 2.0 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP20927.1 - 1e-07 32.1 6.5 8.9e-07 29.1 6.4 2.1 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KFP20927.1 - 0.00095 19.0 6.7 0.032 14.1 3.9 2.5 2 0 0 2 2 2 2 PHD-finger zf-Sec23_Sec24 PF04810.15 KFP20927.1 - 1.2 9.2 0.1 1.2 9.2 0.1 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger CEBP_ZZ PF16366.5 KFP20927.1 - 1.8 8.8 9.1 0.18 12.0 4.2 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RCC1 PF00415.18 KFP20928.1 - 3.5e-62 206.8 26.2 7e-15 55.4 2.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP20928.1 - 3.5e-33 112.7 31.5 5.5e-10 38.8 2.3 6.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFP20928.1 - 2.3e-22 79.3 0.6 2e-20 73.1 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KFP20928.1 - 1.3e-06 28.4 1.1 0.007 16.5 0.1 3.3 2 1 1 3 3 3 2 BTB And C-terminal Kelch PQQ_3 PF13570.6 KFP20928.1 - 1.2 9.8 5.1 18 5.9 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Arf PF00025.21 KFP20929.1 - 1e-52 178.1 0.0 1.1e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP20929.1 - 3.6e-11 43.3 0.0 4.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFP20929.1 - 5.1e-11 42.3 0.0 3.2e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFP20929.1 - 1.1e-10 41.3 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP20929.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFP20929.1 - 9.9e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP20929.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arm PF00514.23 KFP20930.1 - 6.4e-88 286.4 17.1 1.2e-12 47.3 0.3 9.3 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KFP20930.1 - 3.7e-24 84.0 2.4 9.6e-23 79.5 3.3 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFP20930.1 - 3.8e-24 84.7 1.3 1.4e-08 35.1 0.2 6.3 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 KFP20930.1 - 7.6e-18 64.7 0.3 9.8e-07 29.1 0.0 6.3 3 2 4 8 8 8 3 HEAT repeats HEAT PF02985.22 KFP20930.1 - 1e-17 62.7 6.5 0.0032 17.6 0.0 6.8 7 0 0 7 7 6 3 HEAT repeat Adaptin_N PF01602.20 KFP20930.1 - 8.3e-09 34.5 0.1 1.5e-08 33.7 0.1 1.3 1 1 0 1 1 1 1 Adaptin N terminal region IBB PF01749.20 KFP20930.1 - 1.3e-07 32.0 0.8 3.2e-07 30.7 0.8 1.8 1 0 0 1 1 1 1 Importin beta binding domain Atx10homo_assoc PF09759.9 KFP20930.1 - 1.2e-05 25.3 1.9 1.8 8.7 0.0 4.8 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KFP20930.1 - 1.2e-05 25.0 0.4 6.1 6.2 0.0 4.3 2 1 2 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.8 KFP20930.1 - 1.6e-05 25.0 0.6 1.3 9.2 0.1 4.3 4 1 1 5 5 5 1 V-ATPase subunit H Cnd1 PF12717.7 KFP20930.1 - 2.8e-05 24.2 0.4 0.29 11.2 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 KFP20930.1 - 7.1e-05 22.3 0.4 0.011 15.0 0.1 2.5 1 1 1 2 2 2 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 KFP20930.1 - 0.019 15.4 0.1 14 6.2 0.0 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 KFP20930.1 - 0.022 14.2 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 Mo25-like DRIM PF07539.12 KFP20930.1 - 0.1 10.9 0.1 5.6 5.1 0.0 2.4 2 0 0 2 2 2 0 Down-regulated in metastasis Proteasom_PSMB PF10508.9 KFP20930.1 - 0.13 10.7 0.5 0.83 8.1 0.1 2.4 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit RPEL PF02755.15 KFP20930.1 - 0.14 11.9 0.2 23 4.9 0.1 2.7 2 0 0 2 2 2 0 RPEL repeat DUF1981 PF09324.10 KFP20930.1 - 0.17 11.8 0.5 2.5 8.0 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) DCB PF16213.5 KFP20930.1 - 0.21 11.2 0.8 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 CTNNBL PF08216.11 KFP20930.1 - 0.21 11.8 2.0 33 4.7 0.0 3.8 4 2 1 5 5 4 0 Catenin-beta-like, Arm-motif containing nuclear SPRY PF00622.28 KFP20931.1 - 6.9e-17 61.7 0.0 8.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 SPRY domain BTB_2 PF02214.22 KFP20933.1 - 5.7e-20 71.5 0.1 1.5e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFP20933.1 - 0.0028 17.7 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MoaE PF02391.17 KFP20934.1 - 2.5e-40 137.3 0.1 3.1e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 MoaE protein RWP-RK PF02042.15 KFP20934.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 RWP-RK domain Integrin_alpha2 PF08441.12 KFP20935.1 - 8.4e-53 179.9 10.0 1.4e-52 179.1 10.0 1.4 1 1 0 1 1 1 1 Integrin alpha VWA PF00092.28 KFP20935.1 - 5.1e-40 137.6 1.1 8.5e-40 136.9 1.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.23 KFP20935.1 - 3.4e-17 62.2 7.7 3.7e-08 33.3 0.8 3.6 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.6 KFP20935.1 - 1.2e-13 51.7 0.1 2.6e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.6 KFP20935.1 - 2.7e-07 31.1 5.4 0.0089 16.6 0.2 4.0 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KFP20935.1 - 7.4e-06 26.1 3.7 0.17 12.2 0.2 5.0 5 0 0 5 5 5 2 FG-GAP repeat LYRIC PF15686.5 KFP20935.1 - 0.0088 15.6 0.2 0.013 15.0 0.2 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Integrin_alpha PF00357.20 KFP20935.1 - 0.036 14.0 3.8 0.089 12.8 3.8 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region eRF1_1 PF03463.15 KFP20937.1 - 4.7e-51 172.1 0.1 7.6e-51 171.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KFP20937.1 - 1.2e-36 126.0 0.1 1.9e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFP20937.1 - 3.2e-26 92.0 0.1 9.1e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 RVT_1 PF00078.27 KFP20938.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PARP PF00644.20 KFP20942.1 - 2.7e-14 53.2 0.3 6.1e-14 52.1 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 KFP20942.1 - 3.6e-05 23.9 0.1 0.00013 22.2 0.1 2.0 1 0 0 1 1 1 1 ARTD15 N-terminal domain GON PF08685.11 KFP20943.1 - 0.2 11.5 0.0 0.22 11.4 0.0 1.0 1 0 0 1 1 1 0 GON domain Ig_3 PF13927.6 KFP20944.1 - 2e-16 60.4 0.6 8.7e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP20944.1 - 3.2e-13 49.6 0.0 1.4e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KFP20944.1 - 1.1e-11 44.7 0.1 8.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP20944.1 - 4e-11 43.1 0.1 0.00032 21.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP20944.1 - 3.4e-10 40.1 0.2 6.9e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP20944.1 - 2.2e-06 27.8 0.0 0.055 13.7 0.0 2.3 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain V-set_CD47 PF08204.11 KFP20944.1 - 0.00012 22.1 0.6 0.01 15.8 0.3 2.6 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Ig_5 PF16681.5 KFP20944.1 - 0.00055 20.3 0.2 0.046 14.1 0.0 2.6 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set_2 PF15910.5 KFP20944.1 - 0.14 12.3 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 ICOS V-set domain C2-set_2 PF08205.12 KFP20948.1 - 1.4e-17 63.5 0.1 3.8e-17 62.1 0.0 1.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KFP20948.1 - 5.1e-12 46.2 0.3 1.9e-07 31.5 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP20948.1 - 4.9e-10 39.4 0.0 3.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP20948.1 - 3.7e-08 33.6 0.0 0.00015 22.0 0.1 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP20948.1 - 0.00051 20.1 0.1 0.041 14.0 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP20948.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C1-set PF07654.15 KFP20948.1 - 0.034 14.5 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C1-set domain V-set PF07686.17 KFP20949.1 - 2.7e-06 27.5 0.4 0.031 14.4 0.3 2.3 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.16 KFP20949.1 - 0.075 13.1 0.0 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain RTP801_C PF07809.11 KFP20949.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region Abhydrolase_1 PF00561.20 KFP20950.1 - 6.7e-11 42.3 0.2 6.7e-10 39.0 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP20950.1 - 1.9e-09 37.1 0.0 1.1e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP20950.1 - 1.8e-08 35.3 0.0 2.4e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFP20950.1 - 1.1e-07 31.5 0.0 1.8e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 KFP20950.1 - 0.0024 17.1 0.0 0.0088 15.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2920) UPF0227 PF05728.12 KFP20950.1 - 0.0069 16.3 0.0 0.034 14.1 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0227) Vint PF14623.6 KFP20950.1 - 0.017 15.0 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Hint-domain Ser_hydrolase PF06821.13 KFP20950.1 - 0.023 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase BAAT_C PF08840.11 KFP20950.1 - 0.034 14.1 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CH PF00307.31 KFP20951.1 - 1.2e-21 77.0 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KFP20951.1 - 2.4e-14 52.6 6.4 2.4e-14 52.6 6.4 1.8 2 0 0 2 2 2 1 Calponin family repeat V-set PF07686.17 KFP20953.1 - 4e-09 36.6 0.0 4.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP20953.1 - 2.6e-05 24.2 0.0 3.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KFP20953.1 - 0.0002 21.5 0.1 0.00055 20.1 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP20953.1 - 0.00026 21.5 0.0 0.0004 20.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP20954.1 - 2.7e-13 50.3 3.0 1.6e-07 31.8 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP20954.1 - 1.4e-12 47.6 2.2 1e-09 38.4 0.3 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP20954.1 - 8.2e-12 45.0 0.2 4.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.17 KFP20954.1 - 3.8e-11 43.1 0.2 7.4e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP20954.1 - 9.8e-07 29.0 3.6 0.0076 16.6 1.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP20954.1 - 0.0056 16.7 0.2 2.2 8.4 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP20954.1 - 0.0057 16.2 0.5 0.017 14.7 0.1 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Lep_receptor_Ig PF06328.11 KFP20954.1 - 0.0081 16.1 0.6 0.36 10.8 0.1 2.5 2 1 0 2 2 2 1 Ig-like C2-type domain C1-set PF07654.15 KFP20954.1 - 0.13 12.7 1.1 0.63 10.4 0.1 2.4 2 1 1 3 3 3 0 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFP20954.1 - 0.41 10.9 2.3 2.3 8.5 0.2 2.4 1 1 1 2 2 2 0 T-cell surface glycoprotein CD3 delta chain G6B PF15096.6 KFP20955.1 - 0.028 14.2 0.1 0.31 10.8 0.0 1.9 1 1 0 2 2 2 0 G6B family LST1 PF05083.13 KFP20955.1 - 0.045 14.0 0.5 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 LST-1 protein AKAP95 PF04988.12 KFP20956.1 - 0.00013 22.3 0.6 0.00018 21.8 0.6 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFP20956.1 - 0.0034 17.7 1.8 0.0044 17.3 1.1 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.16 KFP20956.1 - 0.011 15.8 1.6 0.36 10.9 0.2 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain HV_small_capsid PF17086.5 KFP20956.1 - 0.06 13.6 0.1 0.19 12.0 0.0 1.8 1 1 1 2 2 2 0 Small capsid protein of Herpesviridae ADD_ATRX PF17981.1 KFP20956.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-C2H2_12 PF18658.1 KFP20956.1 - 0.23 11.1 1.4 0.37 10.4 0.2 1.9 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-met PF12874.7 KFP20956.1 - 2 8.9 6.0 38 4.9 6.0 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFP20958.1 - 5.9e-08 32.7 39.2 0.022 15.2 1.9 6.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP20958.1 - 2.8e-05 24.6 43.4 0.026 15.3 2.6 7.4 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP20958.1 - 0.0092 16.3 5.4 0.0092 16.3 5.4 4.5 3 1 1 4 4 4 1 C2H2-type zinc ribbon DUF1178 PF06676.11 KFP20958.1 - 0.12 12.7 5.1 4.9 7.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-met PF12874.7 KFP20958.1 - 0.3 11.5 13.6 0.52 10.8 0.6 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KFP20958.1 - 2.7 8.1 24.4 0.076 13.1 4.0 3.7 3 0 0 3 3 3 0 BED zinc finger zf-MYND PF01753.18 KFP20958.1 - 6.9 6.8 10.1 2.7 8.1 4.8 3.1 2 0 0 2 2 2 0 MYND finger zf-LYAR PF08790.11 KFP20958.1 - 7.3 6.6 8.6 18 5.3 0.1 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF4518 PF15008.6 KFP20959.1 - 9e-93 310.4 0.0 1e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Pkinase_Tyr PF07714.17 KFP20960.1 - 2.1e-99 332.0 0.0 2.4e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP20960.1 - 3.3e-49 167.6 0.0 4.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP20960.1 - 1e-15 58.4 0.1 1.9e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 KFP20960.1 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFP20960.1 - 0.0031 16.5 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP20960.1 - 0.029 13.2 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Laminin_G_1 PF00054.23 KFP20961.1 - 3.9e-32 111.2 0.2 5.2e-25 88.2 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.24 KFP20961.1 - 7.6e-23 81.5 0.0 5.7e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.15 KFP20961.1 - 1.1e-18 67.2 51.6 2.6e-08 33.9 1.7 4.9 4 1 0 4 4 4 3 Calcium-binding EGF domain Gla PF00594.20 KFP20961.1 - 6.6e-17 61.4 9.7 6.6e-17 61.4 9.7 2.3 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.6 KFP20961.1 - 1e-14 54.5 52.4 3.6e-07 30.3 9.6 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP20961.1 - 1.2e-12 47.8 47.7 1.1e-06 28.8 6.0 4.6 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.7 KFP20961.1 - 4.1e-08 33.3 35.4 0.0034 17.6 4.6 4.6 4 0 0 4 4 4 4 EGF domain hEGF PF12661.7 KFP20961.1 - 5.6e-06 26.8 36.4 0.0053 17.3 2.8 5.2 4 1 1 5 5 5 3 Human growth factor-like EGF cEGF PF12662.7 KFP20961.1 - 1e-05 25.4 34.8 0.0028 17.6 1.1 5.6 5 0 0 5 5 5 4 Complement Clr-like EGF-like LNP1 PF15419.6 KFP20961.1 - 0.19 12.0 0.8 5.4 7.2 1.4 2.3 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Arf PF00025.21 KFP20962.1 - 4.7e-42 143.4 0.9 1.8e-41 141.5 0.0 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFP20962.1 - 1.5e-07 31.6 0.0 4.5e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP20962.1 - 4.9e-07 29.5 0.0 9.2e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP20962.1 - 7.9e-06 25.4 0.0 7.9e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP20962.1 - 4.9e-05 23.4 0.5 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KFP20962.1 - 0.00015 21.0 0.0 0.00015 21.0 0.0 3.3 2 2 1 3 3 3 1 G-protein alpha subunit Mitofilin PF09731.9 KFP20962.1 - 0.0047 15.8 15.5 0.0061 15.5 15.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Syntaxin PF00804.25 KFP20963.1 - 3.5e-61 206.4 20.5 3.5e-61 206.4 20.5 1.5 2 0 0 2 2 2 1 Syntaxin HGD-D PF06050.13 KFP20963.1 - 0.003 17.4 3.6 0.003 17.4 3.6 1.9 1 1 1 2 2 2 1 2-hydroxyglutaryl-CoA dehydratase, D-component SNARE PF05739.19 KFP20963.1 - 0.0051 16.8 1.3 0.022 14.7 0.0 2.5 3 0 0 3 3 3 1 SNARE domain Terminase_6C PF17289.2 KFP20963.1 - 0.0064 16.6 1.6 0.099 12.7 0.2 2.5 1 1 1 2 2 2 1 Terminase RNaseH-like domain ALO PF04030.14 KFP20963.1 - 0.0066 16.3 2.1 0.0076 16.1 1.0 1.6 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase SKA2 PF16740.5 KFP20963.1 - 0.019 14.8 18.8 0.032 14.0 3.8 3.9 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 DUF4988 PF16378.5 KFP20963.1 - 0.48 10.1 12.4 0.56 9.9 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function Syntaxin-6_N PF09177.11 KFP20963.1 - 2.3 8.8 15.1 0.14 12.7 2.7 2.9 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Methyltr_RsmB-F PF01189.17 KFP20964.1 - 1.9e-30 106.0 0.0 2.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFP20964.1 - 0.0006 20.0 0.1 0.0031 17.7 0.1 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase PDZ PF00595.24 KFP20965.1 - 9.2e-07 29.1 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP20965.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Clathrin_bdg PF15045.6 KFP20966.1 - 1.3e-32 111.6 0.1 4.6e-32 109.8 0.1 2.0 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking SERTA PF06031.13 KFP20967.1 - 5.6e-18 64.3 2.2 1.2e-17 63.2 2.2 1.6 1 0 0 1 1 1 1 SERTA motif DUF4279 PF14106.6 KFP20967.1 - 0.091 13.0 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) GET2 PF08690.10 KFP20967.1 - 0.17 11.6 6.5 0.22 11.1 6.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4521 PF15021.6 KFP20967.1 - 0.23 11.3 7.4 0.1 12.5 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4521) RVT_1 PF00078.27 KFP20970.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF PF00008.27 KFP20971.1 - 8.3e-77 253.0 286.6 5.1e-09 36.3 6.5 18.7 20 0 0 20 20 20 14 EGF-like domain hEGF PF12661.7 KFP20971.1 - 3.4e-45 151.2 244.5 7.7e-06 26.4 7.5 20.5 22 0 0 22 22 22 14 Human growth factor-like EGF MNNL PF07657.13 KFP20971.1 - 1.6e-27 95.3 1.4 1.6e-27 95.3 1.4 6.7 8 2 0 8 8 8 1 N terminus of Notch ligand DSL PF01414.19 KFP20971.1 - 2.2e-24 85.5 6.2 2.2e-24 85.5 6.2 13.8 12 2 2 14 14 14 3 Delta serrate ligand EGF_2 PF07974.13 KFP20971.1 - 3.5e-18 65.7 321.7 0.0008 19.7 6.8 20.0 20 0 0 20 20 20 13 EGF-like domain EGF_CA PF07645.15 KFP20971.1 - 4.5e-06 26.8 21.4 4.8e-05 23.5 7.1 19.8 9 4 11 20 20 20 10 Calcium-binding EGF domain Saf_2TM PF18303.1 KFP20971.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain NUDIX PF00293.28 KFP20972.1 - 0.00028 21.0 0.2 0.0023 18.0 0.2 2.0 1 1 0 1 1 1 1 NUDIX domain ESPR PF13018.6 KFP20972.1 - 0.073 12.9 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system TFIIB PF00382.19 KFP20977.1 - 2e-32 111.1 0.0 6e-16 58.3 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KFP20977.1 - 4.9e-27 94.2 11.0 4.9e-27 94.2 11.0 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KFP20977.1 - 1e-07 31.8 0.2 0.0006 19.6 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 KFP20977.1 - 0.0017 18.4 0.2 0.0048 16.9 0.2 1.7 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain TFIIB_C_1 PF18542.1 KFP20977.1 - 0.062 13.3 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 SNAD2 PF18745.1 KFP20977.1 - 0.12 12.1 1.9 0.25 11.0 1.9 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 PPPI_inhib PF14895.6 KFP20978.1 - 2.4e-43 148.7 0.0 3.4e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor HSP70 PF00012.20 KFP20979.1 - 1.7e-263 875.3 10.9 1.9e-263 875.1 10.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFP20979.1 - 2.4e-17 62.7 0.7 9.3e-16 57.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFP20979.1 - 0.00064 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFP20979.1 - 0.00075 19.9 2.7 1.5 9.3 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA CRIC_ras_sig PF10534.9 KFP20979.1 - 0.0028 17.8 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras Hydantoinase_A PF01968.18 KFP20979.1 - 0.022 14.0 0.8 0.06 12.6 0.2 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SHS2_FTSA PF02491.20 KFP20979.1 - 0.3 11.5 1.5 8.9 6.8 0.3 2.7 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA BTB PF00651.31 KFP20980.1 - 7.7e-20 71.2 1.6 7.7e-20 71.2 1.6 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.6 KFP20980.1 - 4e-11 42.8 60.8 0.14 13.0 0.1 10.2 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP20980.1 - 3.5e-08 33.5 64.1 0.036 14.5 0.1 10.4 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP20980.1 - 0.00071 19.9 2.6 0.00071 19.9 2.6 8.6 9 1 0 9 9 8 3 Zinc-finger double domain zf_UBZ PF18439.1 KFP20980.1 - 0.0068 16.0 39.6 0.094 12.3 0.1 8.8 8 1 1 9 9 9 3 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KFP20980.1 - 0.022 15.1 25.1 0.85 10.0 0.1 5.1 4 1 1 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP20980.1 - 0.027 14.8 0.2 0.027 14.8 0.2 8.3 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFP20980.1 - 0.028 14.4 21.6 2.8 8.0 2.7 5.6 3 1 1 5 5 5 0 CpXC protein zf-met PF12874.7 KFP20980.1 - 0.029 14.8 43.0 0.047 14.1 0.4 9.3 8 1 0 8 8 8 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP20980.1 - 0.38 11.1 44.2 0.078 13.3 3.1 7.7 3 2 5 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KFP20980.1 - 4.1 7.3 11.7 8.2 6.4 0.1 5.0 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) FTHFS PF01268.19 KFP20982.1 - 1.8e-260 864.9 0.0 2.6e-260 864.4 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KFP20982.1 - 5.8e-67 224.0 1.2 5.8e-67 224.0 1.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFP20982.1 - 3.6e-32 111.1 0.1 9.1e-32 109.8 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ERbeta_N PF12497.8 KFP20984.1 - 1.2e-53 179.7 8.0 2.1e-53 179.0 8.0 1.4 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.30 KFP20984.1 - 1.9e-34 119.1 1.4 2.9e-34 118.5 1.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP20984.1 - 1.9e-29 101.9 15.4 4.2e-29 100.8 15.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) N6-adenineMlase PF10237.9 KFP20992.1 - 4.7e-57 192.3 0.0 5.9e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KFP20992.1 - 0.0005 19.8 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CRM1_C PF08767.11 KFP20993.1 - 2.3e-05 23.7 1.1 2.3e-05 23.7 1.1 2.3 2 0 0 2 2 2 1 CRM1 C terminal Pkinase PF00069.25 KFP20995.1 - 2.3e-61 207.5 0.1 2.8e-39 135.1 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP20995.1 - 6.6e-29 101.0 0.1 3.8e-20 72.3 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.24 KFP20995.1 - 5.3e-05 23.8 2.4 0.00018 22.1 2.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain UBA PF00627.31 KFP20995.1 - 0.00015 21.6 0.4 0.00028 20.7 0.4 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Haspin_kinase PF12330.8 KFP20995.1 - 0.00054 19.0 1.5 0.001 18.1 1.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP20995.1 - 0.0039 17.1 0.1 0.047 13.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP20995.1 - 0.01 15.2 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP20995.1 - 0.024 13.6 0.1 0.047 12.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KFP20995.1 - 0.039 13.3 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Cadherin_tail PF15974.5 KFP20995.1 - 0.2 12.0 5.4 0.094 13.0 0.2 2.7 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region SAP18 PF06487.12 KFP20996.1 - 1.6e-19 70.5 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) MRP-63 PF14978.6 KFP20997.1 - 7.7e-38 129.0 6.5 8.7e-38 128.8 6.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 DHHC PF01529.20 KFP20998.1 - 2.5e-36 124.7 16.0 2.5e-36 124.7 16.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 KFP20998.1 - 1.3 9.2 6.3 2.4 8.3 6.3 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger EF-hand_7 PF13499.6 KFP20999.1 - 1.1e-12 48.2 12.0 2.3e-05 24.8 0.1 4.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 KFP20999.1 - 1.9e-09 37.3 12.9 2.9e-06 27.0 0.0 5.8 6 1 1 7 7 7 2 EF-hand domain pair EF-hand_1 PF00036.32 KFP20999.1 - 1.6e-08 33.5 14.7 0.00026 20.3 0.2 5.7 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 KFP20999.1 - 6.4e-08 31.9 8.1 0.00093 18.9 0.2 4.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_4 PF12763.7 KFP20999.1 - 0.011 15.7 1.2 0.051 13.5 0.2 2.7 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KFP20999.1 - 0.015 14.8 5.2 4.2 7.0 0.2 3.9 3 0 0 3 3 3 0 EF hand MHC_I PF00129.18 KFP20999.1 - 0.019 14.6 0.4 0.042 13.4 0.4 1.6 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 FGF PF00167.18 KFP21000.1 - 1.9e-47 160.4 0.3 2.3e-47 160.2 0.3 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Sarcoglycan_1 PF04790.13 KFP21002.1 - 9.1e-82 274.3 0.0 1.1e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.9 KFP21002.1 - 0.0067 16.3 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) HEPN PF05168.14 KFP21003.1 - 1.4e-09 38.1 0.1 5.6e-09 36.1 0.1 2.1 1 0 0 1 1 1 1 HEPN domain HATPase_c_3 PF13589.6 KFP21003.1 - 0.0023 17.8 0.1 52 3.7 0.0 4.9 3 2 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.31 KFP21003.1 - 0.0037 17.4 0.3 0.012 15.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain DUF4368 PF14287.6 KFP21003.1 - 0.011 16.0 0.1 0.052 13.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) SDP_N PF12278.8 KFP21003.1 - 0.068 13.3 0.2 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Sex determination protein N terminal TNFR_c6 PF00020.18 KFP21004.1 - 2.1e-08 34.4 16.4 8.6e-06 26.1 4.3 5.4 5 1 0 5 5 5 2 TNFR/NGFR cysteine-rich region C1q PF00386.21 KFP21005.1 - 1.7e-37 128.5 0.0 2.1e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP21005.1 - 2.1e-29 101.0 78.5 1.5e-10 40.7 25.9 3.6 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP21005.1 - 2.8e-05 24.0 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain RhoGEF PF00621.20 KFP21006.1 - 1.3e-45 155.8 5.7 1.3e-45 155.8 5.7 1.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP21006.1 - 1.2e-10 41.8 0.5 2.7e-10 40.7 0.5 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KFP21006.1 - 2.7e-10 39.7 2.1 5.3e-10 38.7 2.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP21006.1 - 5.6e-10 38.9 0.1 1e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP21006.1 - 1.1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.6 KFP21006.1 - 0.0038 17.3 0.3 0.079 13.1 0.1 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain Myosin_TH1 PF06017.13 KFP21006.1 - 0.0058 16.3 0.8 0.011 15.5 0.8 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding TRA-1_regulated PF02343.16 KFP21007.1 - 0.037 14.1 0.5 0.94 9.5 0.0 2.5 2 0 0 2 2 2 0 TRA-1 regulated protein R03H10.4 WTX PF09422.10 KFP21008.1 - 9.2e-137 456.9 17.1 1.2e-113 380.7 10.5 2.2 1 1 1 2 2 2 2 WTX protein Myotub-related PF06602.14 KFP21009.1 - 1.9e-143 477.6 0.1 3.1e-143 477.0 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KFP21009.1 - 0.002 18.0 0.1 0.036 13.9 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP21009.1 - 0.0047 16.5 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP21009.1 - 0.023 14.6 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Nucleoporin_FG2 PF15967.5 KFP21010.1 - 0 1020.7 56.2 0 1020.5 56.2 1.0 1 0 0 1 1 1 1 Nucleoporin FG repeated region FapA PF03961.13 KFP21010.1 - 0.0076 14.9 5.9 0.053 12.1 0.3 2.1 2 0 0 2 2 2 2 Flagellar Assembly Protein A Tox-ODYAM1 PF15642.6 KFP21010.1 - 0.016 14.2 6.1 0.022 13.8 6.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF1043 PF06295.12 KFP21010.1 - 0.2 11.6 9.0 2.6 8.1 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) PSY3 PF16836.5 KFP21010.1 - 0.22 11.0 2.6 0.13 11.8 0.3 1.7 2 0 0 2 2 2 0 Shu complex component Psy3, DNA-binding description DUF1664 PF07889.12 KFP21010.1 - 0.64 10.1 7.1 3.6 7.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KFP21010.1 - 1.8 8.6 8.1 3 8.0 1.1 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PHM7_cyt PF14703.6 KFP21010.1 - 2.2 8.5 10.5 1.7 8.8 7.1 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CENP-F_leu_zip PF10473.9 KFP21010.1 - 2.6 8.1 14.4 2.7 8.0 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KFP21010.1 - 3.3 7.9 12.1 2.6 8.2 1.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KFP21010.1 - 5.5 6.3 16.6 0.32 10.4 3.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Shisa PF13908.6 KFP21011.1 - 5.1e-22 79.0 5.3 8.2e-22 78.4 5.2 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Gag_MA PF01140.19 KFP21011.1 - 0.018 14.8 1.2 0.027 14.2 0.5 1.6 1 1 1 2 2 2 0 Matrix protein (MA), p15 Rhabdo_glycop PF00974.18 KFP21011.1 - 0.097 11.1 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PhoLip_ATPase_C PF16212.5 KFP21012.1 - 2.2e-73 247.1 15.7 2.2e-73 247.1 15.7 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP21012.1 - 1.9e-19 69.1 0.8 1.9e-19 69.1 0.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFP21012.1 - 2.7e-14 53.0 0.0 1e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP21012.1 - 2e-12 47.0 0.0 1e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFP21012.1 - 9.9e-08 32.5 0.5 0.00093 19.5 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Colicin_im PF03857.13 KFP21012.1 - 0.0024 17.8 0.2 0.0024 17.8 0.2 2.7 2 0 0 2 2 2 1 Colicin immunity protein Hydrolase_3 PF08282.12 KFP21012.1 - 0.012 15.3 0.4 0.042 13.6 0.2 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 KFP21013.1 - 6.2e-13 48.9 8.2 1e-12 48.2 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFP21013.1 - 7.8e-10 38.9 7.2 1.7e-09 37.8 7.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KFP21013.1 - 3.6e-08 33.1 6.9 5.7e-08 32.5 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP21013.1 - 1.5e-07 31.0 5.2 1.5e-07 31.0 5.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFP21013.1 - 2.5e-07 30.5 7.8 4.1e-07 29.8 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP21013.1 - 1.1e-05 25.4 1.7 2.4e-05 24.3 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFP21013.1 - 6.8e-05 22.7 4.7 0.00011 22.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP21013.1 - 9e-05 22.4 6.5 0.00015 21.7 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP21013.1 - 0.0039 17.0 5.5 0.0074 16.1 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFP21013.1 - 0.0045 17.0 1.6 0.0045 17.0 1.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KFP21013.1 - 0.049 13.4 4.6 0.084 12.7 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFP21013.1 - 0.19 11.4 5.5 0.31 10.7 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFP21013.1 - 0.39 11.1 6.2 0.69 10.3 6.2 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KFP21013.1 - 2.4 8.3 7.2 6 7.1 7.1 1.8 1 1 0 1 1 1 0 RING-variant domain Pkinase PF00069.25 KFP21014.1 - 7.9e-56 189.3 0.1 9.8e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21014.1 - 3.5e-20 72.4 0.0 5.7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP21014.1 - 0.0059 16.6 0.1 0.0094 15.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP21014.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFP21014.1 - 0.12 11.3 0.1 0.63 9.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Myb_DNA-binding PF00249.31 KFP21015.1 - 0.0013 18.8 0.0 0.0059 16.8 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP21015.1 - 0.041 14.1 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain FANCM-MHF_bd PF16783.5 KFP21016.1 - 5.3e-48 161.9 4.5 1.6e-47 160.4 4.5 1.9 1 0 0 1 1 1 1 FANCM to MHF binding domain Helicase_C PF00271.31 KFP21016.1 - 2.3e-18 66.5 0.3 1.1e-17 64.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC4 PF02732.15 KFP21016.1 - 5e-10 39.8 2.2 1.2e-09 38.6 0.3 2.6 2 0 0 2 2 2 1 ERCC4 domain DEAD PF00270.29 KFP21016.1 - 4e-05 23.5 0.0 9.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFP21016.1 - 0.00013 22.0 0.0 0.00045 20.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_2 PF12826.7 KFP21016.1 - 0.14 12.3 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif SOUL PF04832.12 KFP21017.1 - 6.4e-36 124.1 0.0 7.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein FKBP_C PF00254.28 KFP21018.1 - 1.2e-14 54.4 1.0 3.7e-13 49.6 1.0 2.2 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_14 PF13428.6 KFP21019.1 - 3.6e-12 46.0 0.3 3.5 8.7 0.0 7.1 6 1 2 8 8 8 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFP21019.1 - 0.00018 21.5 7.8 0.51 10.3 0.5 5.1 4 2 1 5 5 5 2 Mad3/BUB1 homology region 1 Suf PF05843.14 KFP21019.1 - 0.00021 21.4 6.0 0.0043 17.1 0.2 3.6 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KFP21019.1 - 0.0003 21.0 1.3 0.55 10.6 0.2 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP21019.1 - 0.00032 21.3 0.0 0.067 13.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP21019.1 - 0.0014 19.1 0.0 6.4 7.4 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP21019.1 - 0.0067 16.5 4.8 3.3 8.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP21019.1 - 0.073 13.7 0.9 96 4.0 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFP21019.1 - 0.79 9.7 3.0 33 4.5 0.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat CLASP_N PF12348.8 KFP21020.1 - 3.7e-13 49.6 1.6 1.4e-05 24.7 0.1 3.4 3 0 0 3 3 3 3 CLASP N terminal NUC173 PF08161.12 KFP21020.1 - 0.00038 20.2 2.8 0.096 12.3 0.1 2.9 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 KFP21020.1 - 0.0088 16.2 1.9 32 5.2 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat DUF445 PF04286.12 KFP21020.1 - 0.018 14.8 5.8 0.66 9.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF445) ParcG PF10274.9 KFP21020.1 - 0.027 14.6 1.4 0.34 11.0 0.6 2.6 2 1 0 2 2 2 0 Parkin co-regulated protein Adaptin_N PF01602.20 KFP21020.1 - 0.08 11.5 3.1 0.087 11.4 0.3 2.4 3 0 0 3 3 3 0 Adaptin N terminal region Dopey_N PF04118.14 KFP21020.1 - 0.099 11.7 1.7 15 4.6 0.0 3.0 2 1 2 4 4 4 0 Dopey, N-terminal COX4 PF02936.14 KFP21020.1 - 0.56 10.2 1.9 1.2 9.2 1.9 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF1978 PF09321.10 KFP21020.1 - 0.69 9.2 10.3 2.2 7.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) SSF PF00474.17 KFP21021.1 - 5.6e-26 91.3 19.4 7.9e-26 90.8 19.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family L6_membrane PF05805.12 KFP21022.1 - 1.9e-68 229.8 20.5 2.1e-68 229.7 20.5 1.0 1 0 0 1 1 1 1 L6 membrane protein Cu-oxidase_3 PF07732.15 KFP21024.1 - 3.3e-31 107.7 1.0 2.1e-10 40.7 0.0 5.1 5 0 0 5 5 5 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFP21024.1 - 7.3e-24 84.1 10.5 2.4e-12 46.8 4.1 6.0 5 1 0 5 5 5 3 Multicopper oxidase 7tm_1 PF00001.21 KFP21028.1 - 4.2e-51 173.8 22.0 5e-51 173.5 22.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP21028.1 - 1.7e-17 63.6 20.9 2.1e-17 63.4 20.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP21028.1 - 2.5e-05 24.2 15.4 3.4e-05 23.7 15.4 1.2 1 0 0 1 1 1 1 Olfactory receptor Mre11_DNA_bind PF04152.14 KFP21029.1 - 3.1e-48 164.3 0.4 3.1e-48 164.3 0.4 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KFP21029.1 - 1.8e-15 58.0 1.5 3.2e-15 57.2 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP21029.1 - 1.7e-05 25.1 0.0 0.00017 21.8 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_4 PF13637.6 KFP21030.1 - 1.1e-31 108.8 5.2 1.2e-14 54.5 0.2 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP21030.1 - 2.3e-31 108.2 5.1 1.1e-17 64.4 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP21030.1 - 3.5e-25 87.3 3.6 8.6e-10 38.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFP21030.1 - 4.7e-23 78.8 1.8 2.1e-06 27.6 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP21030.1 - 1.6e-22 79.3 8.9 8.2e-10 38.8 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Angiomotin_C PF12240.8 KFP21032.1 - 1.6e-91 305.5 40.7 3.9e-91 304.2 18.2 3.4 2 1 1 3 3 3 2 Angiomotin C terminal NPV_P10 PF05531.12 KFP21032.1 - 1.1 9.7 3.6 1.6 9.2 1.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cwf_Cwc_15 PF04889.12 KFP21033.1 - 5.3e-76 255.6 22.0 7e-76 255.2 22.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein UPF0524 PF15823.5 KFP21033.1 - 0.55 9.6 2.6 0.42 10.0 1.0 1.6 1 1 0 1 1 1 0 UPF0524 of C3orf70 PA26 PF04636.13 KFP21034.1 - 3.6e-204 678.7 0.6 4.1e-204 678.5 0.6 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.20 KFP21034.1 - 0.002 18.2 0.0 0.006 16.6 0.0 1.9 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family FAM76 PF16046.5 KFP21035.1 - 2.2e-91 306.3 33.8 2.6e-91 306.1 33.8 1.0 1 0 0 1 1 1 1 FAM76 protein Macoilin PF09726.9 KFP21035.1 - 0.086 11.4 25.2 0.11 11.0 25.2 1.1 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 KFP21035.1 - 0.3 11.4 11.6 0.68 10.3 11.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MPS2 PF17060.5 KFP21035.1 - 0.66 9.2 13.5 0.88 8.8 11.7 2.0 1 1 0 1 1 1 0 Monopolar spindle protein 2 Kinesin_assoc PF16183.5 KFP21035.1 - 0.67 10.1 6.1 0.32 11.1 1.3 2.1 2 0 0 2 2 2 0 Kinesin-associated Metal_resist PF13801.6 KFP21035.1 - 1.7 8.8 7.1 12 6.1 2.2 2.3 2 0 0 2 2 2 0 Heavy-metal resistance DUF3552 PF12072.8 KFP21035.1 - 2.5 7.5 23.1 0.02 14.3 13.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) NicO PF03824.16 KFP21035.1 - 2.6 7.3 7.4 4.5 6.5 7.4 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2614 PF11023.8 KFP21035.1 - 3.1 7.9 8.4 1.1 9.3 1.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain bZIP_2 PF07716.15 KFP21035.1 - 5.1 7.2 10.1 2.8 8.1 4.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Cep57_CLD PF14073.6 KFP21036.1 - 3.9e-68 229.0 39.1 3.9e-68 229.0 39.1 2.4 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 KFP21036.1 - 8.2e-21 74.2 2.9 8.2e-21 74.2 2.9 4.2 3 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Lebercilin PF15619.6 KFP21036.1 - 0.0099 15.6 7.6 0.0099 15.6 7.6 3.5 3 1 1 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease Tsi6 PF18660.1 KFP21036.1 - 0.87 9.7 4.7 0.48 10.5 0.4 2.9 2 1 0 2 2 2 0 Tsi6 Myotub-related PF06602.14 KFP21037.1 - 1.3e-153 511.1 0.0 1.7e-153 510.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 KFP21037.1 - 7.1e-19 67.8 0.0 1.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 KFP21037.1 - 0.00024 20.8 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 KFP21037.1 - 0.00099 18.9 0.1 0.0023 17.7 0.1 1.6 1 0 0 1 1 1 1 Myotubularin-associated protein DSPc PF00782.20 KFP21037.1 - 0.004 17.0 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP21037.1 - 0.031 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family NYD-SP28_assoc PF14775.6 KFP21037.1 - 0.044 13.9 5.8 0.78 9.9 0.9 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF1343 PF07075.11 KFP21041.1 - 0.041 13.2 0.2 0.094 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1343) CSD PF00313.22 KFP21042.1 - 2.6e-14 52.8 0.1 4.7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain PMP22_Claudin PF00822.20 KFP21043.1 - 5.1e-17 62.2 7.0 6.2e-17 62.0 7.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP21043.1 - 4.8e-11 42.8 9.6 1.3e-10 41.4 9.6 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction FAM70 PF14967.6 KFP21043.1 - 0.0026 17.3 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 FAM70 protein L_HMGIC_fpl PF10242.9 KFP21043.1 - 0.0093 16.2 5.3 0.016 15.4 5.3 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein TMEM100 PF16311.5 KFP21043.1 - 0.059 13.0 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 PMP22_Claudin PF00822.20 KFP21044.1 - 6.1e-25 88.0 1.5 7.2e-25 87.8 1.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP21044.1 - 1.2e-11 44.8 4.4 1.4e-11 44.5 4.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 KFP21044.1 - 0.014 15.2 1.4 0.014 15.2 1.4 1.4 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF1218 PF06749.12 KFP21044.1 - 0.027 15.0 1.9 0.19 12.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) SK_channel PF03530.14 KFP21044.1 - 0.091 12.8 0.4 0.12 12.3 0.4 1.2 1 0 0 1 1 1 0 Calcium-activated SK potassium channel DUF2207 PF09972.9 KFP21044.1 - 0.16 10.7 0.3 0.21 10.3 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CD20 PF04103.15 KFP21044.1 - 0.32 11.1 6.6 0.65 10.1 6.6 1.8 1 1 0 1 1 1 0 CD20-like family Trp_oprn_chp PF09534.10 KFP21044.1 - 0.37 10.6 4.6 5.6 6.7 4.6 2.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4064 PF13273.6 KFP21044.1 - 3.1 8.1 8.5 6.9 7.0 5.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) 2OG-FeII_Oxy_3 PF13640.6 KFP21045.1 - 1.4e-11 45.1 0.0 7e-11 42.9 0.0 2.1 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP21045.1 - 2.8e-09 37.4 0.0 5.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KFP21045.1 - 7.3e-06 25.7 5.7 0.0059 16.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP21045.1 - 5.1e-05 22.9 1.1 0.01 15.6 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP21045.1 - 0.004 17.9 0.1 0.65 11.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP21045.1 - 0.0074 16.8 0.2 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.6 KFP21045.1 - 0.042 14.5 0.0 0.092 13.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2452 PF10504.9 KFP21046.1 - 2.5e-59 199.2 0.1 2.8e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Ras PF00071.22 KFP21047.1 - 2.9e-50 170.0 0.0 3.2e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21047.1 - 5.6e-20 71.7 0.0 7.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP21047.1 - 2.2e-06 27.3 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 KFP21047.1 - 0.00047 20.4 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial zf-H2C2_2 PF13465.6 KFP21048.1 - 1.5e-36 123.2 91.3 1.9e-07 31.2 0.4 14.5 14 1 0 14 14 14 11 Zinc-finger double domain zf-C2H2 PF00096.26 KFP21048.1 - 4.5e-34 115.0 99.3 1.4e-05 25.2 0.6 14.7 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21048.1 - 3.7e-27 92.7 108.4 0.0082 16.9 0.2 15.2 15 0 0 15 15 15 13 C2H2-type zinc finger BTB PF00651.31 KFP21048.1 - 3.8e-07 30.3 0.6 0.0015 18.8 0.0 2.8 1 1 1 2 2 2 2 BTB/POZ domain zf-C2H2_jaz PF12171.8 KFP21048.1 - 0.00036 20.7 64.4 0.88 9.9 0.7 13.8 15 0 0 15 15 15 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP21048.1 - 0.0077 16.2 0.4 0.0077 16.2 0.4 13.9 14 0 0 14 14 14 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP21048.1 - 0.024 14.4 0.1 0.024 14.4 0.1 7.4 8 1 0 8 8 7 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KFP21048.1 - 0.084 13.6 48.0 0.37 11.6 3.2 7.2 4 2 1 7 7 7 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFP21048.1 - 0.088 12.6 0.1 0.088 12.6 0.1 9.4 10 0 0 10 10 10 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFP21048.1 - 0.25 12.0 53.2 2.4 8.9 4.7 7.7 1 1 4 7 7 7 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KFP21048.1 - 5.9 7.4 68.4 3.2 8.2 0.9 12.7 14 0 0 14 14 13 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KFP21048.1 - 6.4 6.5 50.8 4.6 6.9 0.1 11.9 12 0 0 12 12 12 0 Ubiquitin-Binding Zinc Finger Pkinase_Tyr PF07714.17 KFP21049.1 - 3.2e-93 311.8 0.0 4.3e-93 311.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.19 KFP21049.1 - 8.4e-67 224.6 0.0 1.3e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.25 KFP21049.1 - 4.7e-45 154.0 0.0 6.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP21049.1 - 1.5e-31 108.5 0.1 1.1e-15 57.7 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.6 KFP21049.1 - 8.3e-21 74.7 0.0 1.9e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.30 KFP21049.1 - 2.3e-19 69.6 0.1 4.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP21049.1 - 7.1e-16 58.1 0.0 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pur_ac_phosph_N PF16656.5 KFP21049.1 - 7.7e-08 32.8 0.2 2.6e-06 27.9 0.3 2.6 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KFP21049.1 - 1.1e-06 28.7 0.4 0.0008 19.5 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III domain SusE PF14292.6 KFP21049.1 - 6.3e-06 26.4 0.0 0.0073 16.5 0.2 2.4 2 0 0 2 2 2 2 SusE outer membrane protein Ephrin_rec_like PF07699.13 KFP21049.1 - 0.0003 20.5 5.3 0.0003 20.5 5.3 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like DUF2369 PF10179.9 KFP21049.1 - 0.0017 18.7 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) Kdo PF06293.14 KFP21049.1 - 0.005 16.2 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Interfer-bind PF09294.10 KFP21049.1 - 0.0076 16.6 0.1 0.059 13.7 0.1 2.4 3 0 0 3 3 2 1 Interferon-alpha/beta receptor, fibronectin type III Haspin_kinase PF12330.8 KFP21049.1 - 0.0095 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF3300 PF11737.8 KFP21049.1 - 0.15 11.6 1.9 2.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) C1q PF00386.21 KFP21050.1 - 5.6e-34 117.1 0.0 6.9e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP21050.1 - 7.6e-13 48.0 39.9 1.5e-08 34.3 24.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.18 KFP21050.1 - 0.018 15.0 0.4 0.27 11.2 0.0 2.1 1 1 1 2 2 2 0 TNF(Tumour Necrosis Factor) family C1q PF00386.21 KFP21051.1 - 7.8e-17 61.7 0.2 9.3e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP21051.1 - 3.3e-10 39.6 27.9 1.5e-06 27.8 9.7 2.1 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Pkinase_Tyr PF07714.17 KFP21052.1 - 1.5e-99 332.5 0.0 1.7e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP21052.1 - 2.3e-49 168.1 0.0 2.8e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP21052.1 - 1.5e-13 51.5 1.0 2.6e-13 50.6 1.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP21052.1 - 0.008 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFP21052.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP21052.1 - 0.097 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Beta-lactamase PF00144.24 KFP21054.1 - 2.5e-36 125.6 0.0 3.9e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase zf-HC5HC2H PF13771.6 KFP21055.1 - 3.5e-14 52.8 3.7 3.5e-14 52.8 3.7 3.7 4 2 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFP21055.1 - 1.8e-08 34.5 9.4 1.8e-08 34.5 9.4 3.6 2 1 1 3 3 3 1 PHD-zinc-finger like domain Toxin_6 PF05453.12 KFP21055.1 - 1.6 9.2 10.3 21 5.7 4.5 3.1 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family Mod_r PF07200.13 KFP21056.1 - 1.6e-11 44.5 0.2 2.6e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein WBS_methylT PF12589.8 KFP21057.1 - 1.7e-20 73.5 4.2 2.5e-20 73.0 4.2 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KFP21057.1 - 2.2e-10 41.0 0.0 3.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP21057.1 - 2.5e-09 37.7 0.0 4.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP21057.1 - 0.00052 20.7 0.0 0.00086 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP21057.1 - 0.00087 19.2 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP21057.1 - 0.057 13.2 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Syntaxin PF00804.25 KFP21058.1 - 5.9e-65 218.7 14.6 9.2e-65 218.1 14.6 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFP21058.1 - 5e-22 77.6 4.0 1.8e-21 75.9 1.9 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFP21058.1 - 1.1e-11 44.9 6.1 1.1e-11 44.9 6.1 2.4 1 1 1 2 2 2 1 Syntaxin-like protein RE_NgoFVII PF09565.10 KFP21058.1 - 0.00034 20.0 4.3 0.00068 19.0 4.3 1.5 1 0 0 1 1 1 1 NgoFVII restriction endonuclease Prominin PF05478.11 KFP21058.1 - 0.0012 16.9 13.1 0.078 10.9 13.3 2.1 1 1 0 1 1 1 1 Prominin GNVR PF13807.6 KFP21058.1 - 0.0079 16.1 0.1 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Ferritin PF00210.24 KFP21058.1 - 0.0089 16.0 1.0 0.0089 16.0 1.0 1.8 2 0 0 2 2 2 1 Ferritin-like domain DUF948 PF06103.11 KFP21058.1 - 0.015 15.6 4.7 7.2 6.9 0.5 3.8 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 KFP21058.1 - 0.021 15.1 2.2 1.8 8.8 0.2 3.6 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Laminin_II PF06009.12 KFP21058.1 - 0.022 14.8 1.9 0.022 14.8 1.9 2.4 2 1 0 2 2 2 0 Laminin Domain II SIMPL PF04402.14 KFP21058.1 - 0.025 15.0 4.4 0.068 13.6 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Lzipper-MIP1 PF14389.6 KFP21058.1 - 0.026 14.8 4.5 0.033 14.5 0.2 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GlutR_dimer PF00745.20 KFP21058.1 - 0.066 13.7 6.1 4.3 7.8 1.2 2.7 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Syntaxin-6_N PF09177.11 KFP21058.1 - 0.12 13.0 11.9 0.057 14.0 3.9 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CorA PF01544.18 KFP21058.1 - 0.17 11.1 10.1 0.37 10.0 2.8 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Sec34 PF04136.15 KFP21058.1 - 0.19 11.6 9.8 3.6 7.5 3.5 3.2 2 1 1 3 3 3 0 Sec34-like family DUF2508 PF10704.9 KFP21058.1 - 0.22 11.7 3.1 0.98 9.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) PspA_IM30 PF04012.12 KFP21058.1 - 0.36 10.4 11.3 0.047 13.3 5.3 2.2 2 1 0 2 2 2 0 PspA/IM30 family YtxH PF12732.7 KFP21058.1 - 0.4 11.2 8.1 0.43 11.1 1.7 3.2 2 1 1 3 3 3 0 YtxH-like protein MCPsignal PF00015.21 KFP21058.1 - 0.46 10.3 9.3 6.1 6.6 0.2 3.0 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Nup54 PF13874.6 KFP21058.1 - 0.62 10.2 10.5 27 4.8 8.1 2.9 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Phage_GPO PF05929.11 KFP21058.1 - 0.71 9.5 7.2 2.6 7.6 4.5 2.7 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase LOH1CR12 PF10158.9 KFP21058.1 - 0.75 9.8 7.6 4.6 7.3 0.7 2.6 2 1 0 2 2 2 0 Tumour suppressor protein HAUS6_N PF14661.6 KFP21058.1 - 0.76 9.3 9.7 4.7 6.7 7.8 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Lge1 PF11488.8 KFP21058.1 - 0.87 9.8 8.5 0.86 9.8 0.1 3.0 3 1 0 3 3 2 0 Transcriptional regulatory protein LGE1 Uso1_p115_C PF04871.13 KFP21058.1 - 0.96 9.8 16.6 0.47 10.8 7.6 2.9 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF16 PF01519.16 KFP21058.1 - 0.98 9.9 12.9 0.38 11.3 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Med9 PF07544.13 KFP21058.1 - 1 9.5 8.5 0.74 9.9 2.0 3.3 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF848 PF05852.11 KFP21058.1 - 1.1 9.4 12.2 0.37 10.9 4.6 2.7 2 2 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FapA PF03961.13 KFP21058.1 - 1.1 7.8 15.5 0.077 11.6 7.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1910 PF08928.10 KFP21058.1 - 1.2 9.2 13.5 0.38 10.7 1.0 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1910) COG5 PF10392.9 KFP21058.1 - 1.3 9.2 8.6 2.6 8.2 0.7 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF745 PF05335.13 KFP21058.1 - 1.5 8.5 5.7 2.6 7.7 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Lipoprotein_2 PF00921.17 KFP21058.1 - 1.7 8.2 8.1 0.12 11.9 1.6 2.2 3 0 0 3 3 3 0 Borrelia lipoprotein Ead_Ea22 PF13935.6 KFP21058.1 - 1.8 9.2 9.9 0.56 10.9 2.5 2.6 2 1 0 2 2 2 0 Ead/Ea22-like protein Herpes_UL25 PF01499.16 KFP21058.1 - 2.2 6.7 5.6 1 7.8 1.9 1.9 1 1 1 2 2 2 0 Herpesvirus UL25 family Fib_alpha PF08702.10 KFP21058.1 - 2.5 8.3 15.3 1.9 8.7 5.8 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF148 PF02520.17 KFP21058.1 - 2.7 8.1 11.2 0.11 12.6 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 Fez1 PF06818.15 KFP21058.1 - 2.9 8.3 17.1 3.7 7.9 0.9 2.2 2 0 0 2 2 2 0 Fez1 FlaC_arch PF05377.11 KFP21058.1 - 3.2 8.2 15.0 7.5 7.0 2.1 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFP21058.1 - 3.3 7.8 13.2 4.4 7.4 3.3 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 KFP21058.1 - 4.1 8.1 8.3 2.5 8.8 2.4 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) DUF4600 PF15372.6 KFP21058.1 - 4.3 7.8 11.6 0.75 10.2 5.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) TMPIT PF07851.13 KFP21058.1 - 5 6.3 12.2 2.5e+02 0.7 12.1 2.3 1 1 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.13 KFP21058.1 - 8.3 7.1 8.6 9.5 6.9 1.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) UPF0697 PF15117.6 KFP21059.1 - 1.3e-22 79.7 0.2 1.4e-22 79.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0697 B9-C2 PF07162.11 KFP21060.1 - 1.8e-51 174.7 0.0 3.2e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4175 PF13779.6 KFP21060.1 - 0.073 11.0 1.1 0.1 10.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) WD40 PF00400.32 KFP21062.1 - 2.9e-20 72.2 2.0 4.4e-05 24.2 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFP21062.1 - 0.0014 17.6 0.6 0.16 10.9 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP21062.1 - 0.046 13.6 0.1 1.4 8.8 0.0 2.8 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Polysacc_deac_1 PF01522.21 KFP21062.1 - 0.085 12.8 0.2 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide deacetylase Syndecan PF01034.20 KFP21062.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain WSD PF15613.6 KFP21063.1 - 1.9e-21 76.4 0.0 1.9e-21 76.4 0.0 4.9 4 1 0 4 4 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Bromodomain PF00439.25 KFP21063.1 - 4.8e-21 74.6 1.5 6.3e-21 74.2 0.2 2.0 2 0 0 2 2 2 1 Bromodomain WAC_Acf1_DNA_bd PF10537.9 KFP21063.1 - 1.3e-18 67.4 0.7 1.3e-18 67.4 0.7 2.6 2 0 0 2 2 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 KFP21063.1 - 3e-12 46.2 3.9 9.4e-12 44.6 3.9 1.9 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 KFP21063.1 - 1.6e-08 33.9 2.1 2.8e-08 33.1 0.1 2.6 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 KFP21063.1 - 0.0009 19.5 1.5 0.0014 18.9 0.3 2.0 2 0 0 2 2 2 1 DDT domain zf-RING_2 PF13639.6 KFP21063.1 - 0.025 14.9 5.4 0.066 13.6 5.4 1.8 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.6 KFP21063.1 - 0.038 13.6 0.4 0.11 12.1 0.4 1.8 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 KFP21063.1 - 0.11 12.5 1.6 0.3 11.1 1.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFP21063.1 - 0.69 10.2 5.8 2.6 8.4 5.8 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFP21063.1 - 9.3 6.1 6.6 45 3.9 6.6 2.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FKBP_C PF00254.28 KFP21064.1 - 1.2e-15 57.6 0.0 4.4e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KFP21064.1 - 1.3e-10 40.5 6.7 0.0005 20.0 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFP21064.1 - 1.1e-08 35.3 2.4 3.4e-05 24.0 1.5 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP21064.1 - 2.7e-05 23.8 4.6 0.02 14.7 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP21064.1 - 9.7e-05 22.3 1.4 0.0032 17.6 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP21064.1 - 0.00021 21.7 1.0 0.0008 19.9 0.7 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP21064.1 - 0.00046 20.8 0.7 0.052 14.2 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP21064.1 - 0.00079 19.3 1.7 0.97 9.6 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP21064.1 - 0.0015 18.7 3.8 0.03 14.6 2.6 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFP21064.1 - 0.0024 17.7 2.1 0.012 15.4 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP21064.1 - 0.008 16.2 1.8 1.1 9.4 0.1 2.4 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KFP21064.1 - 0.013 15.1 0.6 0.1 12.3 0.1 2.6 2 1 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 KFP21064.1 - 0.049 14.0 0.9 3.6 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Couple_hipA PF13657.6 KFP21064.1 - 0.084 13.5 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 HipA N-terminal domain TPR_14 PF13428.6 KFP21064.1 - 0.09 13.7 0.9 4.1 8.5 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 KFP21065.1 - 5.4e-33 114.3 0.0 8.4e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFP21065.1 - 0.005 17.0 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KFP21065.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain tRNA_bind_3 PF17176.4 KFP21065.1 - 0.02 15.2 0.4 0.08 13.2 0.1 2.1 2 0 0 2 2 2 0 tRNA-binding domain Angiomotin_C PF12240.8 KFP21065.1 - 0.048 13.2 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Angiomotin C terminal Ubie_methyltran PF01209.18 KFP21065.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family POM121 PF15229.6 KFP21066.1 - 1.5e-105 352.1 21.1 1.5e-105 352.1 21.1 2.9 3 1 0 3 3 3 1 POM121 family ANTH PF07651.16 KFP21067.1 - 9.9e-69 231.4 7.2 2.7e-67 226.7 0.1 2.5 2 0 0 2 2 2 2 ANTH domain I_LWEQ PF01608.17 KFP21067.1 - 9.7e-54 181.8 9.0 9.7e-54 181.8 9.0 3.3 2 1 1 3 3 3 1 I/LWEQ domain HIP1_clath_bdg PF16515.5 KFP21067.1 - 2.6e-26 92.1 12.8 2.6e-26 92.1 12.8 5.5 4 2 1 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 KFP21067.1 - 0.017 15.4 58.6 0.21 11.8 24.6 4.2 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KFP21067.1 - 0.15 12.5 51.0 0.03 14.8 27.7 3.5 2 1 1 3 3 3 0 Fez1 Pox_A_type_inc PF04508.12 KFP21067.1 - 0.75 9.7 5.3 24 5.0 0.0 4.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat IL8 PF00048.20 KFP21068.1 - 5.7e-23 80.8 0.4 5.7e-23 80.8 0.4 1.3 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFP21070.1 - 7.3e-24 83.7 1.0 8e-24 83.6 1.0 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like An_peroxidase PF03098.15 KFP21071.1 - 1.9e-182 607.6 0.0 2.2e-182 607.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 KFP21072.1 - 4.7e-183 609.6 0.0 5.5e-183 609.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase GON PF08685.11 KFP21073.1 - 0.2 11.5 0.0 0.22 11.4 0.0 1.0 1 0 0 1 1 1 0 GON domain Spt4 PF06093.13 KFP21074.1 - 2.2e-26 91.8 0.2 2.6e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger ZNRF_3_ecto PF18212.1 KFP21075.1 - 1.1e-49 166.8 0.0 1.8e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain zf-RING_2 PF13639.6 KFP21075.1 - 1.9e-12 47.3 9.1 1.9e-12 47.3 9.1 2.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KFP21075.1 - 2.4e-10 40.0 4.6 2.4e-10 40.0 4.6 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP21075.1 - 4.5e-10 39.2 7.6 1.9e-09 37.2 7.6 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP21075.1 - 2.3e-07 30.6 9.3 3.1e-07 30.2 7.7 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP21075.1 - 6e-07 29.7 11.0 3.6e-06 27.2 11.0 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP21075.1 - 1.1e-05 25.3 5.1 1.1e-05 25.3 5.1 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFP21075.1 - 0.00014 21.8 8.9 0.00015 21.6 6.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP21075.1 - 0.00015 21.5 6.0 0.00046 20.0 6.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFP21075.1 - 0.0047 16.8 4.3 0.016 15.1 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3827 PF12877.7 KFP21075.1 - 0.0049 15.3 0.4 0.0073 14.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) FANCL_C PF11793.8 KFP21075.1 - 0.057 13.6 4.0 0.18 12.0 4.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF5305 PF17231.2 KFP21075.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) zf-ANAPC11 PF12861.7 KFP21075.1 - 0.16 12.0 7.5 0.69 10.0 7.5 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP21075.1 - 3.4 7.4 7.5 12 5.6 7.5 2.0 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KFP21075.1 - 4.5 7.2 12.4 1.6 8.7 6.6 2.6 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.7 KFP21075.1 - 4.9 7.4 8.8 16 5.7 8.8 2.0 1 0 0 1 1 1 0 RING-variant domain HSF_DNA-bind PF00447.17 KFP21077.1 - 0.083 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding Myotub-related PF06602.14 KFP21078.1 - 1.1e-136 455.5 0.0 1.4e-136 455.1 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KFP21078.1 - 0.0032 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP21078.1 - 0.0086 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP21078.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_C14 PF00656.22 KFP21079.1 - 2.3e-43 148.9 0.0 3e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 KFP21079.1 - 1.7e-17 63.2 0.0 3.2e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Abhydrolase_6 PF12697.7 KFP21080.1 - 0.0011 19.6 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Gasdermin PF04598.12 KFP21080.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain DUF2048 PF09752.9 KFP21080.1 - 0.068 12.2 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Septin PF00735.18 KFP21081.1 - 8.6e-125 415.7 0.1 9.9e-125 415.5 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFP21081.1 - 5.9e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP21081.1 - 6e-08 32.8 0.2 2.4e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP21081.1 - 2.7e-06 27.1 0.0 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFP21081.1 - 0.0003 20.2 0.1 0.00078 18.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KFP21081.1 - 0.0027 17.8 1.1 0.54 10.3 0.0 2.6 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 KFP21081.1 - 0.0061 16.2 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21081.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFP21081.1 - 0.015 15.7 0.1 0.027 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFP21081.1 - 0.017 15.6 0.0 0.03 14.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KFP21081.1 - 0.024 14.9 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFP21081.1 - 0.041 13.6 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KFP21081.1 - 0.045 12.9 0.3 3 6.9 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit AAA_25 PF13481.6 KFP21081.1 - 0.13 11.8 0.2 1.6 8.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain SBDS_C PF09377.10 KFP21082.1 - 4.3e-39 133.1 1.2 5.2e-39 132.9 1.2 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain Alpha_Helical PF18489.1 KFP21082.1 - 0.075 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Alpha helical domain Radical_SAM PF04055.21 KFP21083.1 - 6.8e-30 104.6 0.0 3.5e-29 102.3 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.12 KFP21083.1 - 4e-29 100.7 0.1 1.1e-28 99.3 0.1 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 KFP21083.1 - 1.6e-21 77.0 0.0 3.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin HAD PF12710.7 KFP21083.1 - 0.084 13.3 0.0 0.46 10.9 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Adaptin_binding PF10199.9 KFP21083.1 - 0.21 12.2 2.0 0.4 11.3 2.0 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Glycos_transf_2 PF00535.26 KFP21084.1 - 8e-29 100.6 0.0 1.3e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KFP21084.1 - 5.1e-18 65.5 0.1 8.3e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KFP21084.1 - 9.6e-06 25.6 0.0 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KFP21084.1 - 0.036 14.8 0.1 0.17 12.6 0.0 2.0 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Auts2 PF15336.6 KFP21086.1 - 5.7e-106 353.5 16.3 5.7e-106 353.5 16.3 5.9 3 2 1 5 5 5 1 Autism susceptibility gene 2 protein RVT_1 PF00078.27 KFP21093.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACT_7 PF13840.6 KFP21094.1 - 7.5e-35 118.5 0.0 1.8e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 ACT domain RCC1 PF00415.18 KFP21095.1 - 1.4e-52 176.1 15.6 9.9e-10 38.9 0.1 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP21095.1 - 4.7e-32 109.1 32.9 3.6e-07 29.8 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat DUF4479 PF14794.6 KFP21095.1 - 0.2 11.5 0.1 0.79 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) SH3_1 PF00018.28 KFP21096.1 - 2.1e-30 104.0 0.6 6.7e-15 54.4 0.1 3.1 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KFP21096.1 - 3.9e-23 81.0 0.1 2.4e-10 40.1 0.1 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KFP21096.1 - 4.2e-22 77.6 0.0 3.9e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain NECFESHC PF16621.5 KFP21096.1 - 4.8e-22 77.7 10.0 4.8e-22 77.7 10.0 1.9 2 0 0 2 2 2 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 PX PF00787.24 KFP21096.1 - 4.3e-19 68.6 5.8 1.9e-17 63.3 0.6 2.2 2 0 0 2 2 2 2 PX domain hSH3 PF14603.6 KFP21096.1 - 6.6e-05 23.3 0.0 0.077 13.4 0.0 2.6 2 0 0 2 2 2 2 Helically-extended SH3 domain SH3_3 PF08239.11 KFP21096.1 - 0.00013 22.2 1.1 0.024 14.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_6 PF12913.7 KFP21096.1 - 0.031 13.8 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) GTF2I PF02946.14 KFP21097.1 - 2e-191 620.5 13.5 4.1e-33 113.3 0.0 6.2 6 0 0 6 6 6 6 GTF2I-like repeat REV1_C PF16727.5 KFP21097.1 - 0.0032 17.8 0.5 11 6.4 0.0 4.3 4 0 0 4 4 4 1 DNA repair protein REV1 C-terminal domain NRBF2 PF08961.10 KFP21097.1 - 0.077 12.6 0.9 2.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator GTF2I PF02946.14 KFP21098.1 - 3.7e-157 510.7 10.0 5.4e-31 106.5 0.2 5.3 5 0 0 5 5 5 5 GTF2I-like repeat SR-25 PF10500.9 KFP21098.1 - 0.033 13.8 12.6 0.096 12.3 12.6 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAP_GLY PF01302.25 KFP21099.1 - 1.2e-48 163.0 5.2 4.7e-25 87.4 0.4 2.4 2 0 0 2 2 2 2 CAP-Gly domain Strep_SA_rep PF06696.11 KFP21099.1 - 0.45 10.6 6.9 2 8.5 6.9 2.3 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Rep_fac_C PF08542.11 KFP21101.1 - 1e-26 93.2 0.0 2.6e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFP21101.1 - 1.7e-13 51.1 0.1 3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFP21101.1 - 3.4e-12 46.5 0.0 3.3e-10 40.0 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KFP21101.1 - 2.9e-06 27.3 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP21101.1 - 5.7e-06 26.8 0.0 0.00069 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFP21101.1 - 6.8e-06 26.4 0.2 0.028 14.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 KFP21101.1 - 3.3e-05 23.7 0.0 7.6e-05 22.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KFP21101.1 - 4.5e-05 22.9 0.0 0.00064 19.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KFP21101.1 - 5.1e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KFP21101.1 - 7.1e-05 22.7 0.0 8.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFP21101.1 - 0.00074 19.9 0.5 0.0032 17.8 0.5 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFP21101.1 - 0.00079 19.2 0.0 0.0021 17.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFP21101.1 - 0.0012 19.4 0.0 0.0046 17.5 0.0 1.9 1 1 0 2 2 2 1 AAA domain MipZ PF09140.11 KFP21101.1 - 0.0015 17.9 0.1 0.002 17.5 0.1 1.1 1 0 0 1 1 1 1 ATPase MipZ TniB PF05621.11 KFP21101.1 - 0.0019 17.6 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_5 PF07728.14 KFP21101.1 - 0.0039 17.2 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFP21101.1 - 0.0042 16.7 0.3 0.019 14.6 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KFP21101.1 - 0.0054 16.5 0.2 0.016 14.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KFP21101.1 - 0.0073 16.1 1.1 0.43 10.3 0.0 2.6 2 1 1 3 3 3 1 DEAD/DEAH box helicase Rad17 PF03215.15 KFP21101.1 - 0.01 15.8 0.0 0.033 14.1 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KFP21101.1 - 0.012 15.9 0.0 0.036 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain ABC_tran PF00005.27 KFP21101.1 - 0.014 15.9 0.0 0.037 14.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KFP21101.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 KFP21101.1 - 0.032 14.5 0.1 0.055 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KFP21101.1 - 0.038 14.0 0.2 13 5.8 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 KFP21101.1 - 0.039 13.8 0.3 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 KFP21101.1 - 0.05 12.6 0.0 0.09 11.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KFP21101.1 - 0.052 12.8 0.6 1.2 8.3 0.6 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KFP21101.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KFP21101.1 - 0.076 13.4 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DUF4597 PF15366.6 KFP21101.1 - 0.08 12.7 0.7 3.1 7.6 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4597) AAA_23 PF13476.6 KFP21101.1 - 0.088 13.3 0.0 0.13 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFP21101.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein RRM_1 PF00076.22 KFP21102.1 - 2.9e-13 49.4 0.1 4.4e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.13 KFP21103.1 - 6.9e-186 619.7 30.1 6.9e-186 619.7 30.1 2.0 2 1 0 2 2 2 1 DNA polymerase phi ArgoMid PF16487.5 KFP21104.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Mid domain of argonaute MFS_1 PF07690.16 KFP21105.1 - 1.2e-36 126.4 40.6 7.8e-36 123.7 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP21105.1 - 1.3e-13 50.6 26.0 1.9e-13 50.1 26.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KFP21105.1 - 3.6e-13 48.7 22.0 1.2e-05 23.8 10.1 4.3 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KFP21105.1 - 0.0013 17.4 9.1 0.0013 17.4 9.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Ank_2 PF12796.7 KFP21106.1 - 1.7e-81 268.9 25.3 1.9e-12 47.6 2.5 12.0 4 3 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP21106.1 - 2.6e-69 220.9 29.4 5.3e-05 23.3 0.0 20.9 22 0 0 22 22 22 16 Ankyrin repeat Ank_4 PF13637.6 KFP21106.1 - 7.4e-64 211.4 23.0 2.1e-06 28.2 0.5 17.1 7 5 11 19 19 19 12 Ankyrin repeats (many copies) Ank PF00023.30 KFP21106.1 - 1.5e-63 208.6 38.4 1.2e-08 35.0 0.0 20.2 23 0 0 23 23 23 11 Ankyrin repeat Ank_5 PF13857.6 KFP21106.1 - 1.5e-58 194.1 29.8 4.6e-08 33.2 0.0 15.4 11 3 3 15 15 15 10 Ankyrin repeats (many copies) BTB PF00651.31 KFP21106.1 - 3.3e-16 59.5 0.2 1.2e-15 57.7 0.2 2.1 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.21 KFP21106.1 - 7.1e-16 58.1 10.5 1.5e-15 57.0 10.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger BACK PF07707.15 KFP21106.1 - 0.021 14.9 2.4 0.034 14.2 0.3 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch Glyoxalase_4 PF13669.6 KFP21106.1 - 0.12 12.6 0.2 16 5.8 0.0 3.8 4 0 0 4 4 4 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FYVE_2 PF02318.16 KFP21106.1 - 1.5 9.1 11.2 0.37 11.0 7.4 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger ZZ PF00569.17 KFP21107.1 - 2.6e-15 55.9 21.6 2.9e-08 33.4 6.8 3.6 4 0 0 4 4 4 2 Zinc finger, ZZ type ANAPC10 PF03256.16 KFP21107.1 - 2.6e-13 50.0 0.4 6e-13 48.8 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KFP21107.1 - 1.7e-05 24.9 0.1 3.7e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain EF-hand_6 PF13405.6 KFP21107.1 - 0.019 14.8 0.0 0.095 12.7 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KFP21107.1 - 0.022 14.3 0.1 0.061 12.9 0.1 1.9 1 0 0 1 1 1 0 EF hand E1-E2_ATPase PF00122.20 KFP21108.1 - 5e-49 166.3 0.2 5e-49 166.3 0.2 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP21108.1 - 3.3e-45 154.0 3.4 3.3e-45 154.0 3.4 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFP21108.1 - 8.3e-21 73.9 1.0 1.5e-20 73.0 1.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFP21108.1 - 1.5e-18 67.9 0.0 3.9e-17 63.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFP21108.1 - 7.2e-07 29.2 1.3 1.1e-06 28.5 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP21108.1 - 0.0046 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P2X_receptor PF00864.19 KFP21109.1 - 6.7e-162 538.7 0.2 7.9e-162 538.5 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor Dickkopf_N PF04706.12 KFP21109.1 - 0.037 14.5 1.5 0.1 13.1 1.5 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region WAP PF00095.21 KFP21109.1 - 0.13 12.6 4.9 0.1 13.0 2.2 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pkinase PF00069.25 KFP21110.1 - 8.2e-65 218.8 0.0 1e-63 215.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21110.1 - 2.6e-33 115.4 0.0 2.3e-31 109.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFP21110.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP21110.1 - 4.1e-05 22.5 0.0 6.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Mis12 PF05859.12 KFP21112.1 - 2.5e-26 92.3 1.2 2.5e-26 92.3 1.2 1.8 1 1 0 2 2 2 1 Mis12 protein DUF2018 PF09442.10 KFP21112.1 - 0.025 15.6 0.5 0.067 14.2 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) ZapB PF06005.12 KFP21112.1 - 0.044 14.2 4.1 0.044 14.2 4.1 2.8 3 0 0 3 3 3 0 Cell division protein ZapB DUF4296 PF14129.6 KFP21112.1 - 0.18 12.5 3.5 0.15 12.7 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4296) APG17 PF04108.12 KFP21112.1 - 0.23 10.5 8.4 0.14 11.3 3.7 2.0 1 1 0 2 2 2 0 Autophagy protein Apg17 Glu-tRNAGln PF02686.15 KFP21112.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.2 3 0 0 3 3 2 0 Glu-tRNAGln amidotransferase C subunit PilJ PF13675.6 KFP21112.1 - 0.35 10.9 4.7 0.33 11.0 3.2 1.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FlxA PF14282.6 KFP21112.1 - 0.53 10.3 10.0 0.62 10.1 5.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 KFP21112.1 - 0.58 10.3 4.0 1.4 9.1 3.6 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3891 PF13030.6 KFP21112.1 - 0.68 9.7 6.1 0.76 9.5 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3891) OmpH PF03938.14 KFP21112.1 - 0.7 10.2 15.5 2.9 8.2 15.5 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec34 PF04136.15 KFP21112.1 - 1.2 9.0 9.2 0.27 11.1 1.2 2.6 2 1 1 3 3 3 0 Sec34-like family CENP-H PF05837.12 KFP21112.1 - 1.7 9.1 9.7 33 4.9 9.6 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Acetyltransf_11 PF13720.6 KFP21112.1 - 2.9 8.4 4.4 21 5.6 1.0 2.4 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DASH_Spc34 PF08657.10 KFP21112.1 - 4.2 7.1 9.1 3.7 7.3 5.4 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 Prefoldin_2 PF01920.20 KFP21112.1 - 5.3 7.1 15.2 9.9 6.2 0.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit Cep57_MT_bd PF06657.13 KFP21112.1 - 6.3 7.3 13.9 0.81 10.2 1.9 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4140 PF13600.6 KFP21112.1 - 6.9 7.2 6.8 9 6.8 3.7 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DER1 PF04511.15 KFP21113.1 - 1.9e-65 220.4 12.7 2.1e-65 220.2 12.7 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 KFP21113.1 - 1 9.1 3.9 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 Oleosin HA2 PF04408.23 KFP21114.1 - 6.7e-20 71.4 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFP21114.1 - 1.6e-16 60.4 0.0 3.6e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFP21114.1 - 8.5e-14 51.8 0.0 1.8e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFP21114.1 - 1.7e-05 24.6 0.1 3.8e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFP21114.1 - 0.021 15.1 0.0 0.067 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RBM1CTR PF08081.11 KFP21114.1 - 0.044 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 RBM1CTR (NUC064) family MAM33 PF02330.16 KFP21115.1 - 9.5e-43 146.6 4.1 1.1e-42 146.4 4.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein PDDEXK_7 PF04411.12 KFP21115.1 - 0.099 12.6 0.1 0.22 11.5 0.1 1.6 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RPA_interact_C PF14768.6 KFP21116.1 - 1.4e-18 67.2 4.3 2.2e-18 66.6 4.3 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal RPA_interact_M PF14767.6 KFP21116.1 - 3e-09 37.3 8.3 5.4e-09 36.5 8.3 1.4 1 0 0 1 1 1 1 Replication protein A interacting middle DUF5318 PF17249.2 KFP21116.1 - 0.096 12.5 0.9 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5318) Nup88 PF10168.9 KFP21117.1 - 3.1e-290 964.1 0.6 3.5e-290 963.9 0.6 1.0 1 0 0 1 1 1 1 Nuclear pore component Syntaxin-6_N PF09177.11 KFP21117.1 - 0.022 15.3 3.9 0.022 15.3 3.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SH3_10 PF17902.1 KFP21117.1 - 0.089 12.9 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Flagellin_N PF00669.20 KFP21117.1 - 0.14 12.3 0.8 0.33 11.0 0.8 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region YtxH PF12732.7 KFP21117.1 - 0.47 11.0 3.0 5.9 7.5 3.0 2.4 1 1 0 1 1 1 0 YtxH-like protein NOG1_N PF17835.1 KFP21117.1 - 0.67 9.9 9.5 0.068 13.1 2.1 2.2 1 1 1 2 2 2 0 NOG1 N-terminal helical domain FapA PF03961.13 KFP21117.1 - 1 7.9 11.8 1.4 7.4 11.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TolA_bind_tri PF16331.5 KFP21117.1 - 1.4 9.1 10.8 2.5 8.2 3.6 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation Dna2 PF08696.11 KFP21117.1 - 2.8 7.7 10.8 0.67 9.7 5.7 2.1 1 1 1 2 2 2 0 DNA replication factor Dna2 Exonuc_VII_L PF02601.15 KFP21117.1 - 2.9 7.4 10.3 4.8 6.7 10.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 KFP21117.1 - 4.1 7.8 11.5 61 4.0 7.5 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 KFP21117.1 - 6.8 4.5 10.7 10 3.9 10.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rabaptin PF03528.15 KFP21118.1 - 4.4e-255 846.9 45.0 4.4e-255 846.9 45.0 3.0 2 1 1 3 3 3 1 Rabaptin Rab5-bind PF09311.11 KFP21118.1 - 8.4e-137 455.6 63.2 8.4e-137 455.6 63.2 4.0 2 1 2 4 4 4 1 Rabaptin-like protein Fez1 PF06818.15 KFP21118.1 - 0.0019 18.7 23.4 0.0019 18.7 23.4 5.4 2 2 3 5 5 5 2 Fez1 TruB_C_2 PF16198.5 KFP21118.1 - 0.61 10.3 8.0 0.9 9.7 0.3 4.5 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain Roc PF08477.13 KFP21119.1 - 1.1e-09 38.5 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP21119.1 - 1e-06 28.5 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KFP21119.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Collagen PF01391.18 KFP21120.1 - 9.5e-20 70.1 80.1 3.3e-09 36.4 36.5 3.3 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) EMI PF07546.13 KFP21120.1 - 4.6e-18 65.7 11.0 7e-18 65.1 11.0 1.3 1 0 0 1 1 1 1 EMI domain EF-hand_1 PF00036.32 KFP21122.1 - 5.2e-15 53.8 3.8 5.1e-06 25.7 0.9 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KFP21122.1 - 1.4e-10 40.3 3.8 2e-06 27.2 0.8 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFP21122.1 - 1.4e-10 41.4 0.2 9.2e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFP21122.1 - 5e-08 32.7 1.2 0.015 15.1 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KFP21122.1 - 0.0004 19.8 2.2 0.0017 17.7 1.0 2.7 2 0 0 2 2 2 1 EF hand CUT PF02376.15 KFP21124.1 - 1.5e-78 259.0 0.0 5e-25 87.5 0.0 3.9 3 0 0 3 3 3 3 CUT domain Homeodomain PF00046.29 KFP21124.1 - 3.3e-15 55.7 3.5 3.3e-15 55.7 0.7 2.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KFP21124.1 - 1.1e-05 25.2 0.6 4.4e-05 23.3 0.6 2.1 1 0 0 1 1 1 1 Homeobox KN domain DUF5572 PF17733.1 KFP21124.1 - 0.0015 18.3 0.0 26 4.8 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5572) NPV_P10 PF05531.12 KFP21124.1 - 0.023 15.2 12.8 0.029 14.9 1.3 4.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HTH_40 PF14493.6 KFP21124.1 - 0.036 14.5 6.1 5.2 7.6 0.0 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4618 PF15397.6 KFP21124.1 - 4.6 6.6 38.1 0.077 12.4 23.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) CorA PF01544.18 KFP21124.1 - 8.9 5.5 16.5 4.6 6.5 9.4 2.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1168 PF06658.12 KFP21125.1 - 1.4e-45 154.5 12.8 1.5e-45 154.3 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Orai-1 PF07856.12 KFP21126.1 - 4.7e-71 238.0 8.9 5.7e-71 237.8 8.9 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity CopD PF05425.13 KFP21126.1 - 0.18 12.2 5.5 0.47 10.9 0.2 2.3 1 1 1 2 2 2 0 Copper resistance protein D DUF2207 PF09972.9 KFP21126.1 - 0.27 9.9 2.7 0.47 9.2 2.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) 2OG-FeII_Oxy_2 PF13532.6 KFP21127.1 - 0.00025 21.3 0.0 0.00056 20.2 0.0 1.5 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFP21127.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily LRR_4 PF12799.7 KFP21128.1 - 1.1e-07 32.1 6.0 1.1e-07 32.1 6.0 2.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP21128.1 - 4.4e-06 26.4 5.4 0.0015 18.3 0.6 2.7 1 1 1 2 2 2 2 Leucine rich repeat WD40 PF00400.32 KFP21128.1 - 0.00048 20.9 2.5 0.018 15.9 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat LRR_9 PF14580.6 KFP21128.1 - 0.051 13.1 2.7 0.09 12.3 2.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 KFP21128.1 - 0.2 12.3 2.9 4.8 8.1 0.5 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat RNA_pol_L_2 PF13656.6 KFP21129.1 - 1.2e-29 101.9 0.1 1.5e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFP21129.1 - 1.3e-10 40.5 0.0 1.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.9 KFP21129.1 - 0.12 11.9 0.1 0.39 10.2 0.0 1.8 1 1 1 2 2 2 0 SHNi-TPR C2 PF00168.30 KFP21130.1 - 5.2e-44 148.8 0.0 3.5e-27 94.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 KFP21130.1 - 2.4e-35 122.2 0.0 8e-35 120.4 0.0 1.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRCB PF02537.15 KFP21131.1 - 0.014 15.7 1.9 0.18 12.2 0.1 2.3 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) DTC PF18102.1 KFP21133.1 - 1e-61 206.9 0.0 2e-61 206.0 0.0 1.5 1 0 0 1 1 1 1 Deltex C-terminal domain WWE PF02825.20 KFP21133.1 - 2.2e-34 117.8 1.0 1.2e-16 61.1 0.0 2.5 2 0 0 2 2 2 2 WWE domain zf-C3HC4 PF00097.25 KFP21133.1 - 0.0002 21.2 9.4 0.00062 19.6 9.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP21133.1 - 0.0043 17.3 6.2 0.0099 16.1 6.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP21133.1 - 0.0057 16.7 5.1 0.016 15.2 5.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFP21133.1 - 0.0066 16.5 2.1 0.027 14.5 2.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 KFP21133.1 - 0.011 15.9 1.6 0.029 14.5 1.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KFP21133.1 - 0.096 12.5 5.6 0.94 9.3 0.9 2.6 2 0 0 2 2 2 0 RING-like zinc finger PHD PF00628.29 KFP21133.1 - 0.14 12.1 3.7 0.53 10.2 3.7 2.1 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KFP21133.1 - 0.34 11.3 17.0 0.062 13.6 9.3 3.0 2 1 0 2 2 1 0 Ring finger domain zf-RING_5 PF14634.6 KFP21133.1 - 3.9 7.5 12.0 0.53 10.3 7.3 2.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP21133.1 - 9.7 6.1 17.8 0.069 13.0 1.2 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) 14-3-3 PF00244.20 KFP21134.1 - 5.1e-96 320.5 7.1 5.7e-96 320.3 7.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C98 PF15499.6 KFP21134.1 - 0.072 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FlaC_arch PF05377.11 KFP21134.1 - 0.14 12.5 0.8 0.34 11.3 0.8 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HSP20 PF00011.21 KFP21135.1 - 4.9e-24 84.4 0.0 5.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.11 KFP21135.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 YabP family Ldh_1_C PF02866.18 KFP21136.1 - 4.7e-51 173.0 0.0 9.2e-51 172.1 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFP21136.1 - 5e-48 162.8 0.0 7.2e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KFP21136.1 - 0.0025 18.3 0.0 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFP21136.1 - 0.0027 16.7 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KFP21136.1 - 0.093 12.0 0.1 0.51 9.7 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 KFP21136.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DSPc PF00782.20 KFP21137.1 - 4.1e-21 75.2 0.0 6.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KFP21137.1 - 0.00059 20.3 0.1 0.027 15.0 0.1 2.4 1 1 0 1 1 1 1 Rhodanese-like domain TMPIT PF07851.13 KFP21138.1 - 7.4e-154 511.8 19.5 8.4e-154 511.6 19.5 1.0 1 0 0 1 1 1 1 TMPIT-like protein OmpH PF03938.14 KFP21138.1 - 0.13 12.6 2.4 0.26 11.6 2.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DPM3 PF08285.11 KFP21138.1 - 0.24 11.6 2.6 1.5 9.0 0.2 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FAD_binding_1 PF00667.20 KFP21139.1 - 6.6e-82 274.4 0.0 1.1e-81 273.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFP21139.1 - 3.1e-40 137.7 0.1 1.5e-39 135.4 0.3 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KFP21139.1 - 4.9e-19 69.0 0.1 2.9e-18 66.5 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFP21139.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF3755 PF12579.8 KFP21139.1 - 0.18 11.5 0.2 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) Rhomboid PF01694.22 KFP21140.1 - 3.4e-15 56.4 5.8 4.2e-15 56.0 5.8 1.1 1 0 0 1 1 1 1 Rhomboid family MerC PF03203.14 KFP21140.1 - 0.046 14.2 2.8 0.082 13.4 2.8 1.4 1 0 0 1 1 1 0 MerC mercury resistance protein HP_OMP_2 PF02521.14 KFP21140.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane protein RTA1 PF04479.13 KFP21140.1 - 0.16 11.5 4.8 4.2 6.9 0.4 3.0 1 1 2 3 3 3 0 RTA1 like protein TssN PF17555.2 KFP21140.1 - 3.9 6.8 7.1 0.77 9.1 3.0 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssN RRM_1 PF00076.22 KFP21141.1 - 7.7e-13 48.1 0.1 4e-12 45.8 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 KFP21141.1 - 2.7e-08 33.0 5.5 4e-08 32.4 5.5 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others GAS2 PF02187.17 KFP21142.1 - 2.9e-33 113.8 0.2 4.9e-33 113.0 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFP21142.1 - 1.3e-14 54.3 0.0 3e-14 53.1 0.1 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Ras PF00071.22 KFP21143.1 - 2.7e-25 88.8 0.0 5.3e-25 87.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFP21143.1 - 3.7e-08 33.6 0.0 3.5e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP21143.1 - 0.00056 19.4 0.0 0.0091 15.5 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP21143.1 - 0.0022 18.0 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFP21143.1 - 0.021 15.2 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KFP21143.1 - 0.047 13.9 0.0 0.072 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Pex2_Pex12 PF04757.14 KFP21144.1 - 1.6e-44 152.2 2.1 1.9e-44 151.9 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KFP21144.1 - 9e-05 22.3 2.1 0.00017 21.4 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP21144.1 - 0.00057 19.7 1.1 0.0013 18.5 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP21144.1 - 0.019 14.9 1.3 0.037 13.9 1.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP21144.1 - 0.039 14.3 5.0 0.34 11.3 5.2 2.3 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KFP21144.1 - 0.052 13.5 0.6 3.8 7.6 0.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP21144.1 - 0.8 9.6 3.1 31 4.5 0.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP21144.1 - 2.4 8.5 4.5 56 4.1 4.4 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFP21145.1 - 2.5e-12 46.4 12.0 2.5e-12 46.4 12.0 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.9 KFP21145.1 - 9.4e-07 28.9 1.7 0.037 14.0 0.1 2.7 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding FYVE_2 PF02318.16 KFP21145.1 - 0.00031 21.0 6.1 0.00031 21.0 6.1 2.8 2 1 0 2 2 2 1 FYVE-type zinc finger Prok-RING_4 PF14447.6 KFP21145.1 - 0.00056 19.7 11.9 0.00056 19.7 11.9 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SAP PF02037.27 KFP21145.1 - 0.00093 18.9 0.6 0.67 9.8 0.1 2.8 3 0 0 3 3 3 2 SAP domain FYVE PF01363.21 KFP21145.1 - 0.004 17.3 14.1 0.004 17.3 14.1 3.9 3 2 0 3 3 3 1 FYVE zinc finger zf-RING_5 PF14634.6 KFP21145.1 - 0.0074 16.2 12.0 0.0074 16.2 12.0 2.8 3 0 0 3 3 3 1 zinc-RING finger domain Siva PF05458.12 KFP21145.1 - 0.01 15.5 3.2 0.01 15.5 3.2 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-C3HC4_2 PF13923.6 KFP21145.1 - 0.023 14.5 14.3 0.023 14.5 14.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HeH PF12949.7 KFP21145.1 - 0.15 11.8 0.1 63 3.4 0.0 3.3 3 0 0 3 3 3 0 HeH/LEM domain DNA_ligase_A_M PF01068.21 KFP21146.1 - 3.2e-58 196.7 0.0 5.9e-58 195.9 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFP21146.1 - 1.3e-32 113.5 0.2 1.3e-32 113.5 0.2 2.2 3 0 0 3 3 3 1 DNA ligase N terminus LIG3_BRCT PF16759.5 KFP21146.1 - 8.1e-28 96.5 0.0 1.8e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain zf-PARP PF00645.18 KFP21146.1 - 1.3e-23 83.6 1.0 5.5e-23 81.6 1.0 2.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DNA_ligase_A_C PF04679.15 KFP21146.1 - 5.6e-18 65.4 0.0 1.5e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KFP21146.1 - 1.5e-06 28.5 0.2 4.5e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IL8 PF00048.20 KFP21149.1 - 9.9e-15 54.4 4.3 1.1e-14 54.3 4.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.20 KFP21150.1 - 9.1e-14 51.4 1.0 1.2e-13 51.0 1.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like ERM PF00769.19 KFP21151.1 - 3.3e-47 161.4 43.3 3.3e-47 161.4 43.3 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.18 KFP21151.1 - 8.9e-27 93.8 1.3 8.9e-27 93.8 1.3 2.8 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KFP21151.1 - 3.6e-22 78.5 0.2 3.6e-22 78.5 0.2 2.6 3 0 0 3 3 3 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP21151.1 - 6.3e-11 42.1 0.3 3.5e-10 39.7 0.3 2.3 1 0 0 1 1 1 1 FERM N-terminal domain NIPSNAP PF07978.13 KFP21153.1 - 1.5e-38 131.1 1.0 1.4e-32 111.9 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Hydrolase PF00702.26 KFP21154.1 - 4.5e-19 69.6 0.0 6.9e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP21154.1 - 9.4e-13 49.0 0.0 1.6e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFP21154.1 - 8.3e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 KFP21154.1 - 1.3e-06 28.7 0.0 0.0025 17.9 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFP21154.1 - 1.5e-05 24.6 0.0 5.5e-05 22.7 0.0 1.8 2 1 0 2 2 2 1 Putative Phosphatase Acid_phosphat_B PF03767.14 KFP21154.1 - 0.00026 20.7 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 KFP21154.1 - 0.0086 15.8 0.0 0.45 10.2 0.0 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase StbA PF06406.11 KFP21154.1 - 0.019 14.2 0.0 0.064 12.5 0.0 1.7 2 0 0 2 2 2 0 StbA protein Hydrolase_like PF13242.6 KFP21154.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 HAD-hyrolase-like Cpn60_TCP1 PF00118.24 KFP21155.1 - 1e-117 393.8 7.1 4.5e-69 233.4 0.1 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family FGE-sulfatase PF03781.16 KFP21156.1 - 2.5e-60 204.2 4.9 2.9e-60 204.1 4.9 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Pkinase PF00069.25 KFP21157.1 - 1.9e-77 260.2 0.0 2.4e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21157.1 - 1.4e-32 113.0 0.0 1.7e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21157.1 - 7.4e-12 45.2 0.0 4.7e-10 39.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KFP21157.1 - 2.1e-07 30.5 0.1 3.9e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP21157.1 - 1.5e-05 23.9 0.1 0.00022 20.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP21157.1 - 2e-05 23.7 0.3 4e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP21157.1 - 9.8e-05 22.0 0.1 0.00023 20.8 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP21157.1 - 0.00011 22.2 0.3 0.35 10.8 0.3 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFP21157.1 - 0.0034 17.0 0.2 0.41 10.3 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KFP21157.1 - 0.0077 15.8 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Spc110_C PF18520.1 KFP21157.1 - 0.026 14.1 0.3 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain DUF5420 PF17457.2 KFP21157.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5420) YrbL-PhoP_reg PF10707.9 KFP21157.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CHCH PF06747.13 KFP21158.1 - 1.5e-06 28.1 7.8 2.6e-06 27.4 7.8 1.4 1 0 0 1 1 1 1 CHCH domain Nup54_C PF18437.1 KFP21158.1 - 0.19 11.7 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain DUF2076 PF09849.9 KFP21158.1 - 6.8 6.7 19.0 0.55 10.2 7.6 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) VKOR PF07884.14 KFP21159.1 - 2.7e-15 56.6 13.7 3.2e-15 56.4 13.7 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family G3P_acyltransf PF02660.15 KFP21159.1 - 0.35 10.9 8.5 0.45 10.6 8.5 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Tmemb_55A PF09788.9 KFP21159.1 - 1.7 7.7 5.1 2 7.4 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A SPC25 PF06703.11 KFP21159.1 - 5.9 6.6 11.8 3.6 7.3 9.6 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_hydro_2_C PF02836.17 KFP21160.1 - 1.2e-104 349.7 0.0 1.5e-104 349.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFP21160.1 - 1.2e-17 64.3 0.1 2.4e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFP21160.1 - 1.3e-05 25.8 0.4 5.5e-05 23.8 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Lyase_1 PF00206.20 KFP21161.1 - 9.3e-92 307.7 0.1 8.7e-72 242.1 0.0 2.7 2 1 1 3 3 3 2 Lyase ASL_C2 PF14698.6 KFP21161.1 - 4.3e-21 75.5 0.1 2.2e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Get5_bdg PF16843.5 KFP21161.1 - 0.088 12.3 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein TPM_phosphatase PF04536.14 KFP21161.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 TPM domain Lyase_1 PF00206.20 KFP21162.1 - 3.7e-94 315.6 0.0 1.2e-93 314.0 0.0 1.8 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KFP21162.1 - 9.5e-19 67.9 0.1 4.4e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF4164 PF13747.6 KFP21162.1 - 0.027 14.8 2.3 0.17 12.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Get5_bdg PF16843.5 KFP21162.1 - 0.1 12.1 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein APG17 PF04108.12 KFP21162.1 - 2.7 7.0 5.9 29 3.6 0.4 3.0 3 0 0 3 3 3 0 Autophagy protein Apg17 RNA_pol_Rpb4 PF03874.16 KFP21163.1 - 4.9e-10 39.8 0.3 5.9e-10 39.5 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Sulfotransfer_3 PF13469.6 KFP21164.1 - 2.5e-54 185.0 0.0 3.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KFP21164.1 - 2.1e-08 34.0 0.1 2e-07 30.8 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KFP21164.1 - 0.0016 18.3 0.0 0.0083 16.0 0.1 2.2 1 1 1 2 2 2 1 Sulfotransferase domain BTB_2 PF02214.22 KFP21165.1 - 2.5e-20 72.6 0.1 1.4e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KFP21165.1 - 0.0054 16.8 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain VPS9 PF02204.18 KFP21166.1 - 1.6e-29 102.2 0.0 5.1e-29 100.6 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFP21166.1 - 2.3e-21 75.8 1.6 7.2e-21 74.3 1.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 KFP21166.1 - 4.3e-12 45.8 6.8 9e-12 44.7 6.8 1.6 1 0 0 1 1 1 1 A20-like zinc finger SSTK-IP PF15836.5 KFP21166.1 - 0.062 13.4 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Syntaxin PF00804.25 KFP21166.1 - 0.083 12.6 10.0 0.54 9.9 3.2 2.6 2 1 1 3 3 3 0 Syntaxin GIT1_C PF12205.8 KFP21166.1 - 1.2 9.2 7.0 4.9 7.3 0.1 3.6 4 1 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term Mit_KHE1 PF10173.9 KFP21166.1 - 2.5 8.1 6.3 3.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related DUF2116 PF09889.9 KFP21166.1 - 8.2 6.5 6.0 6.9 6.7 2.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TMEM219 PF14940.6 KFP21167.1 - 4.8e-87 291.4 0.5 6.2e-87 291.1 0.5 1.1 1 0 0 1 1 1 1 Transmembrane 219 Omp28 PF11551.8 KFP21167.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Outer membrane protein Omp28 T2SSK PF03934.13 KFP21168.1 - 0.00057 19.4 0.4 0.0029 17.0 0.1 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K LRR_4 PF12799.7 KFP21168.1 - 0.0018 18.7 1.0 0.0099 16.3 0.9 2.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP21168.1 - 0.12 12.5 0.2 0.45 10.7 0.2 2.1 1 0 0 1 1 1 0 Leucine Rich repeat NCBP3 PF10309.9 KFP21170.1 - 8.8e-21 73.5 0.1 2.1e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KFP21170.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain SH3_2 PF07653.17 KFP21171.1 - 1.1e-25 89.1 0.4 4.1e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP21171.1 - 3.9e-19 68.0 1.3 1.5e-15 56.5 0.7 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KFP21171.1 - 4.8e-14 52.0 0.2 8.9e-10 38.3 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain DUF3804 PF12707.7 KFP21171.1 - 0.18 11.5 0.0 0.8 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) 14-3-3 PF00244.20 KFP21172.1 - 9.4e-101 335.9 0.8 1e-100 335.8 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KFP21172.1 - 0.057 11.8 0.5 0.089 11.2 0.5 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Myosin_head PF00063.21 KFP21173.1 - 4.1e-252 838.3 5.7 5.3e-252 837.9 5.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFP21173.1 - 1.4e-32 112.9 1.8 3.1e-32 111.8 1.8 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 KFP21173.1 - 0.0011 18.5 17.3 0.0028 17.3 1.6 3.9 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.6 KFP21173.1 - 0.0048 17.2 0.0 0.065 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP21173.1 - 0.019 15.4 0.0 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KFP21173.1 - 0.026 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KFP21173.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKICH PF17751.1 KFP21174.1 - 3.8e-30 104.5 0.1 7.2e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 SKICH domain Exo_endo_phos PF03372.23 KFP21174.1 - 7.5e-10 38.7 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IP_trans PF02121.18 KFP21175.1 - 1.3e-113 378.6 1.3 1.6e-113 378.4 1.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF5595 PF18077.1 KFP21175.1 - 0.12 12.4 2.3 0.25 11.4 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) RILP PF11461.8 KFP21177.1 - 4.2e-20 71.7 4.9 4.2e-20 71.7 4.9 2.8 3 2 0 3 3 3 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.9 KFP21177.1 - 0.0082 16.4 1.1 0.0082 16.4 1.1 3.2 3 1 0 3 3 3 2 JNK_SAPK-associated protein-1 Leu_zip PF15294.6 KFP21177.1 - 0.016 14.7 11.9 0.02 14.4 11.4 1.5 1 1 0 1 1 1 0 Leucine zipper Ovate PF04844.13 KFP21177.1 - 0.083 12.9 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 Transcriptional repressor, ovate Ribosomal_S7e PF01251.18 KFP21177.1 - 0.68 9.7 6.5 1 9.0 6.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e DIRP PF06584.13 KFP21177.1 - 2.8 8.2 8.0 0.31 11.3 0.4 2.6 2 1 1 3 3 3 0 DIRP Macoilin PF09726.9 KFP21177.1 - 5.2 5.5 12.6 5.6 5.4 12.6 1.2 1 0 0 1 1 1 0 Macoilin family Pyr_redox_2 PF07992.14 KFP21179.1 - 6.3e-41 140.5 0.0 1e-19 70.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFP21179.1 - 2.9e-13 49.6 0.1 6.7e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 KFP21179.1 - 2.8e-09 37.4 0.0 7.1e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox_3 PF13738.6 KFP21179.1 - 9e-06 25.2 0.0 0.0053 16.0 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KFP21179.1 - 5.3e-05 23.1 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 KFP21179.1 - 0.00021 21.8 0.3 0.86 10.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFP21179.1 - 0.0071 15.5 0.1 1.4 7.9 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KFP21179.1 - 0.064 13.5 0.5 0.16 12.2 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFP21179.1 - 0.074 11.7 0.1 13 4.3 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein ssDNA-exonuc_C PF10141.9 KFP21179.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain WD40 PF00400.32 KFP21180.1 - 4.3e-15 55.8 7.1 1.6e-06 28.7 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21180.1 - 0.0071 16.6 0.0 1.1 9.6 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KFP21180.1 - 0.0098 15.5 0.0 0.09 12.3 0.0 2.4 2 1 0 3 3 3 1 PQQ-like domain Serpin PF00079.20 KFP21181.1 - 1.2e-87 294.6 0.3 1.4e-87 294.4 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KFP21182.1 - 6.2e-87 292.3 0.0 7.2e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SET PF00856.28 KFP21183.1 - 8.7e-15 55.5 0.0 7.6e-13 49.2 0.0 3.0 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 KFP21183.1 - 2.3e-08 34.2 1.0 1.5e-05 25.2 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP21183.1 - 1.6e-07 30.9 3.0 0.038 14.1 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat zf-MYND PF01753.18 KFP21183.1 - 5e-07 29.7 14.8 5e-07 29.7 14.8 3.3 3 0 0 3 3 2 1 MYND finger ANAPC3 PF12895.7 KFP21183.1 - 0.00014 22.0 1.6 0.92 9.8 0.0 3.8 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFP21183.1 - 0.00045 20.0 0.2 0.0055 16.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP21183.1 - 0.00076 19.2 0.2 1.2 9.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP21183.1 - 0.0018 19.0 4.7 0.65 11.0 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP21183.1 - 0.0097 16.5 1.5 14 6.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP21183.1 - 0.012 15.6 0.6 0.13 12.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP21183.1 - 0.031 13.6 6.3 0.19 11.1 2.7 2.8 2 1 1 3 3 3 0 MalT-like TPR region Phage_lysozyme PF00959.19 KFP21183.1 - 0.047 14.1 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Phage lysozyme TPR_4 PF07721.14 KFP21183.1 - 0.048 14.3 9.3 0.62 10.9 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFP21183.1 - 0.064 13.8 4.6 2.6 8.6 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFP21183.1 - 0.14 12.2 0.1 1.5 8.9 0.1 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) YfdX PF10938.8 KFP21183.1 - 0.14 12.0 0.5 0.93 9.4 0.1 2.2 2 0 0 2 2 2 0 YfdX protein Cytochrom_B562 PF07361.11 KFP21183.1 - 0.35 11.6 4.2 4.5 8.0 0.2 2.7 2 0 0 2 2 2 0 Cytochrome b562 Rep_fac-A_C PF08646.10 KFP21184.1 - 3.8e-55 185.7 12.8 5.1e-52 175.5 7.8 2.7 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFP21184.1 - 3.8e-39 132.6 1.2 5e-37 125.8 0.7 2.3 2 0 0 2 2 2 2 Replication protein A OB domain Rep-A_N PF04057.12 KFP21184.1 - 1.1e-27 96.0 0.5 2.1e-27 95.1 0.5 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFP21184.1 - 1.9e-12 47.0 0.5 7e-11 42.0 0.0 3.1 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KFP21184.1 - 0.0011 17.0 0.1 0.0025 15.8 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5521) DUF4939 PF16297.5 KFP21184.1 - 0.016 15.1 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) IBR PF01485.21 KFP21184.1 - 0.097 12.9 3.7 0.27 11.5 3.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Diphthamide_syn PF01866.17 KFP21185.1 - 2.3e-83 280.1 0.0 3e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Antimicrobial21 PF14861.6 KFP21185.1 - 4.9 7.0 8.4 0.29 10.9 1.6 2.3 2 0 0 2 2 2 0 Plant antimicrobial peptide EST1_DNA_bind PF10373.9 KFP21186.1 - 4.1e-59 200.4 0.4 1.7e-58 198.3 0.0 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 KFP21186.1 - 1.5e-20 73.8 0.0 1.5e-20 73.8 0.0 3.0 2 0 0 2 2 2 1 PIN domain EST1 PF10374.9 KFP21186.1 - 2.3e-15 57.4 2.0 6.3e-15 56.0 0.4 2.8 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_9 PF18477.1 KFP21186.1 - 0.0024 18.1 0.4 0.33 11.3 0.0 3.3 3 0 0 3 3 3 1 PIN like domain UPF0561 PF10573.9 KFP21186.1 - 0.073 13.2 8.0 0.9 9.7 0.3 3.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 TPR_2 PF07719.17 KFP21186.1 - 0.42 10.9 1.8 5.5 7.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.25 KFP21188.1 - 7.5e-56 189.7 0.9 2.5e-54 184.7 0.9 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RIBIOP_C PF04950.12 KFP21189.1 - 2.1e-127 424.6 0.0 3.2e-127 423.9 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFP21189.1 - 2.2e-21 75.7 0.0 5.3e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain S-antigen PF05756.11 KFP21189.1 - 2.7 8.4 4.0 7 7.1 4.0 1.7 1 0 0 1 1 1 0 S-antigen protein DUF525 PF04379.14 KFP21190.1 - 4.2e-27 94.2 0.1 7.3e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 KFP21190.1 - 4.8e-13 49.4 0.5 2.3e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Kinesin PF00225.23 KFP21191.1 - 7.9e-79 265.0 0.0 9.4e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFP21191.1 - 5.3e-11 42.7 0.0 8.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Hemopexin PF00045.19 KFP21192.1 - 4.3e-51 170.6 17.4 5.8e-17 61.4 0.1 5.3 5 0 0 5 5 5 4 Hemopexin Somatomedin_B PF01033.17 KFP21192.1 - 2.1e-09 37.6 19.3 3.9e-09 36.8 19.3 1.5 1 0 0 1 1 1 1 Somatomedin B domain MFS_1 PF07690.16 KFP21193.1 - 6.1e-09 35.3 21.1 6.1e-09 35.3 21.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Na_sulph_symp PF00939.19 KFP21194.1 - 2.3e-140 468.8 20.2 2.6e-140 468.6 20.2 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFP21194.1 - 2.6e-34 118.8 26.2 1.2e-20 73.9 0.2 3.0 2 1 1 3 3 3 2 Citrate transporter DUF4834 PF16118.5 KFP21194.1 - 0.041 14.8 3.3 7.7 7.5 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) DUF4366 PF14283.6 KFP21194.1 - 0.27 11.3 0.6 0.96 9.5 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Forkhead PF00250.18 KFP21195.1 - 1.3e-34 118.3 1.4 1.6e-34 118.0 0.2 1.9 2 0 0 2 2 2 1 Forkhead domain GMP_PDE_delta PF05351.11 KFP21196.1 - 4.6e-79 264.0 3.1 5.2e-79 263.8 3.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IIGP PF05049.13 KFP21196.1 - 0.11 11.5 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PIG-S PF10510.9 KFP21197.1 - 1e-114 384.2 0.3 1.3e-114 383.9 0.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Glycolytic PF00274.19 KFP21198.1 - 1.4e-186 619.3 0.0 1.5e-186 619.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I AP-5_subunit_s1 PF15001.6 KFP21199.1 - 0.012 15.6 2.5 0.016 15.2 2.5 1.3 1 1 0 1 1 1 0 AP-5 complex subunit sigma-1 Gp58 PF07902.11 KFP21199.1 - 0.12 10.6 0.2 0.13 10.6 0.2 1.0 1 0 0 1 1 1 0 gp58-like protein FAM184 PF15665.5 KFP21199.1 - 0.13 12.0 7.8 0.16 11.7 7.8 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B APG6_N PF17675.1 KFP21199.1 - 1.1 9.8 11.7 1.7 9.2 11.7 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region MukF_M PF17192.4 KFP21200.1 - 0.0052 16.5 2.8 0.0077 16.0 2.8 1.3 1 0 0 1 1 1 1 MukF middle domain GAS PF13851.6 KFP21200.1 - 0.012 15.0 6.5 0.014 14.8 6.5 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glyco_hydro_66 PF13199.6 KFP21200.1 - 0.052 12.2 0.1 0.061 12.0 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Seryl_tRNA_N PF02403.22 KFP21200.1 - 0.052 13.8 4.2 0.061 13.6 4.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PI3K_P85_iSH2 PF16454.5 KFP21200.1 - 0.099 12.2 6.4 0.42 10.2 6.3 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KxDL PF10241.9 KFP21200.1 - 0.29 11.4 5.2 0.4 11.0 1.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 KFP21200.1 - 0.31 11.3 10.0 1.4 9.2 1.8 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 KFP21200.1 - 0.4 9.7 6.6 0.5 9.4 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KFP21200.1 - 0.44 10.4 3.5 0.74 9.6 3.4 1.6 1 1 0 1 1 1 0 Septum formation initiator FapA PF03961.13 KFP21200.1 - 0.65 8.5 1.5 0.69 8.4 1.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 KFP21200.1 - 1.2 9.8 4.8 1.6 9.4 4.8 1.2 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KFP21200.1 - 1.8 9.0 11.8 2.6 8.5 11.8 1.5 1 1 0 1 1 1 0 Cell division protein ZapB SH2_2 PF14633.6 KFP21202.1 - 8.3e-84 280.3 0.4 8.3e-84 280.3 0.4 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 KFP21202.1 - 2e-71 238.6 0.0 6.5e-71 237.0 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KFP21202.1 - 3.2e-50 168.8 0.1 7.6e-50 167.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 KFP21202.1 - 7.3e-26 90.9 2.8 2.2e-25 89.3 2.8 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KFP21202.1 - 2.5e-15 56.8 31.6 2.5e-15 56.8 31.6 8.0 7 1 2 9 9 7 2 Acidic N-terminal SPT6 Tex_N PF09371.10 KFP21202.1 - 1.2e-08 34.9 0.1 0.0045 16.7 0.0 3.2 2 1 0 2 2 2 2 Tex-like protein N-terminal domain HHH_3 PF12836.7 KFP21202.1 - 1.3e-07 31.8 0.0 4.6e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KFP21202.1 - 1.9e-06 28.1 0.1 5.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 KFP21202.1 - 2.7e-06 27.4 0.0 8.5e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 KFP21202.1 - 1.1e-05 26.3 0.1 7.7e-05 23.5 0.1 2.7 1 0 0 1 1 1 1 HHH domain Tex_YqgF PF16921.5 KFP21202.1 - 0.00025 21.5 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain zf-Sec23_Sec24 PF04810.15 KFP21202.1 - 0.16 12.1 0.2 0.47 10.6 0.2 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Ribosomal_L23eN PF03939.13 KFP21203.1 - 2.1e-28 98.3 16.9 4.9e-28 97.1 16.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFP21203.1 - 2.8e-16 59.6 3.3 2.8e-16 59.6 3.3 2.7 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L6 PF00347.23 KFP21203.1 - 0.056 14.1 1.8 0.061 14.0 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L6 TRAM_LAG1_CLN8 PF03798.16 KFP21204.1 - 3e-16 59.8 11.9 3.6e-16 59.5 11.9 1.1 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.25 KFP21205.1 - 9.8e-60 202.1 0.1 1.4e-59 201.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 KFP21205.1 - 7.4e-47 157.8 21.4 2.2e-12 47.4 0.7 8.1 7 1 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 KFP21205.1 - 1.5e-41 142.4 0.1 3e-41 141.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RCC1_2 PF13540.6 KFP21205.1 - 7.9e-20 70.2 32.3 6.1e-06 25.9 0.2 6.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 KFP21205.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP21205.1 - 0.00033 19.7 0.9 0.00054 19.0 0.9 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFP21205.1 - 0.01 15.7 1.0 0.069 13.1 0.9 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP21205.1 - 0.095 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase MATH PF00917.26 KFP21206.1 - 3.2e-05 24.0 0.0 0.022 14.9 0.0 2.0 1 1 1 2 2 2 2 MATH domain FAM222A PF15258.6 KFP21207.1 - 3.5e-280 930.6 38.1 3.9e-280 930.5 38.1 1.0 1 0 0 1 1 1 1 Protein family of FAM222A Flot PF15975.5 KFP21208.1 - 4.7e-10 39.7 9.4 4.7e-10 39.7 9.4 3.4 2 2 2 4 4 4 2 Flotillin YjbH PF06082.11 KFP21208.1 - 0.15 10.8 6.2 0.19 10.5 6.2 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Crystall PF00030.19 KFP21211.1 - 7.2e-60 199.2 6.5 6.5e-30 103.2 0.3 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFP21211.1 - 0.0017 18.3 0.8 0.93 9.5 0.0 2.8 2 0 0 2 2 2 2 Peptidase inhibitor family I36 IL4_i_Ig PF18258.1 KFP21211.1 - 0.0038 17.4 5.3 29 5.0 0.0 4.1 1 1 3 4 4 4 3 Interleukin-4 inducing immunoglobulin-binding domain NUFIP2 PF15293.6 KFP21212.1 - 0 1016.9 26.0 0 1016.8 26.0 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.25 KFP21214.1 - 3.1e-65 220.2 0.0 3.1e-65 220.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21214.1 - 2.3e-44 151.6 1.2 4.9e-44 150.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFP21214.1 - 0.022 14.7 3.2 0.027 14.4 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family TcdB_N PF12918.7 KFP21214.1 - 4.7 7.6 14.1 2 8.8 5.3 4.0 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain MFS_1 PF07690.16 KFP21215.1 - 6e-37 127.4 41.5 1e-21 77.3 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFP21215.1 - 1.1e-06 28.2 2.6 1.1e-06 28.2 2.6 1.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB SEFIR PF08357.11 KFP21216.1 - 1e-32 113.5 0.1 1.3e-32 113.1 0.1 1.2 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.6 KFP21216.1 - 4.1e-05 24.1 0.0 6.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain Pkinase_Tyr PF07714.17 KFP21217.1 - 1.8e-92 309.3 0.0 2.4e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP21217.1 - 2.3e-46 158.3 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP21217.1 - 5.8e-29 100.0 0.3 1.3e-28 98.9 0.3 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP21217.1 - 1.2e-20 72.9 0.4 6.1e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP21217.1 - 4.1e-14 52.2 0.5 1e-13 50.9 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFP21217.1 - 1.1e-11 44.2 0.0 4.2e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP21217.1 - 0.0067 15.4 0.0 0.03 13.3 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 KFP21217.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_3 PF08239.11 KFP21217.1 - 0.02 15.1 0.1 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-RING_14 PF17978.1 KFP21217.1 - 0.083 13.3 0.1 0.41 11.1 0.0 2.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Tubulin PF00091.25 KFP21218.1 - 4.3e-51 173.9 0.0 6e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP21218.1 - 2.7e-30 105.1 0.0 4.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KFP21218.1 - 0.00014 21.2 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 KFP21218.1 - 0.004 16.8 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hist_deacetyl PF00850.19 KFP21225.1 - 8e-86 288.3 0.1 1.1e-85 287.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain 5_nucleotid PF05761.14 KFP21229.1 - 3.6e-43 148.1 0.0 4.4e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFP21229.1 - 0.0012 19.0 0.0 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Ribosomal_S16 PF00886.19 KFP21229.1 - 0.17 12.0 0.5 0.47 10.6 0.1 1.9 3 0 0 3 3 3 0 Ribosomal protein S16 Collagen PF01391.18 KFP21230.1 - 3.8e-69 228.3 287.6 7.1e-08 32.1 21.6 10.3 1 1 7 8 8 8 8 Collagen triple helix repeat (20 copies) C1q PF00386.21 KFP21230.1 - 5.4e-39 133.3 0.1 6.9e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KFP21230.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 BclA C-terminal domain DUF4962 PF16332.5 KFP21231.1 - 1.2e-06 27.4 4.6 1.2e-06 27.4 4.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) SYF2 PF08231.12 KFP21231.1 - 0.041 14.3 0.8 0.093 13.1 0.8 1.5 1 0 0 1 1 1 0 SYF2 splicing factor Hepar_II_III PF07940.13 KFP21231.1 - 0.046 13.3 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Heparinase II/III-like protein DUF3340 PF11818.8 KFP21231.1 - 1.4 9.1 7.8 2.5 8.3 7.8 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Ca_hom_mod PF14798.6 KFP21232.1 - 3.5e-26 91.8 0.1 4.6e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Calcium homeostasis modulator TRAPP PF04051.16 KFP21233.1 - 7.5e-31 106.8 0.0 8.4e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ca_hom_mod PF14798.6 KFP21234.1 - 4.1e-89 298.0 11.5 4.9e-89 297.8 11.5 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator LRR19-TM PF15176.6 KFP21234.1 - 0.093 12.7 0.2 0.33 11.0 0.2 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain OS-D PF03392.13 KFP21234.1 - 0.38 10.9 6.6 0.066 13.3 1.7 2.2 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Ca_hom_mod PF14798.6 KFP21235.1 - 1.1e-83 280.3 3.2 1.3e-83 280.0 3.2 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Comm PF15957.5 KFP21235.1 - 0.098 13.0 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Commissureless DUF2093 PF09866.9 KFP21235.1 - 1.1 8.8 4.1 23 4.5 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2093) DFRP_C PF16543.5 KFP21236.1 - 5.2e-09 36.5 0.6 9.9e-09 35.6 0.6 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 RWD PF05773.22 KFP21236.1 - 5.9e-07 29.8 0.2 1.2e-06 28.8 0.2 1.5 1 0 0 1 1 1 1 RWD domain Arfaptin PF06456.13 KFP21236.1 - 0.0043 16.7 0.0 0.99 8.9 0.0 2.2 2 0 0 2 2 2 2 Arfaptin-like domain TraC_F_IV PF11130.8 KFP21236.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Sulfotransfer_1 PF00685.27 KFP21237.1 - 3.7e-75 252.9 0.2 4.4e-75 252.6 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP21237.1 - 1.3e-08 35.5 0.1 0.00011 22.6 0.0 2.6 3 0 0 3 3 3 2 Sulfotransferase family Peptidase_C78 PF07910.13 KFP21238.1 - 1.1e-70 237.5 0.0 1.7e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KFP21238.1 - 0.0024 17.3 0.4 0.0039 16.7 0.2 1.4 1 1 0 1 1 1 1 Peptidase family C54 PcfK PF14058.6 KFP21238.1 - 0.024 14.9 0.3 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 PcfK-like protein Zn-C2H2_12 PF18112.1 KFP21238.1 - 0.2 12.2 4.1 1.2 9.7 4.1 2.3 1 1 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Arm PF00514.23 KFP21239.1 - 1.2e-91 298.3 15.5 7.7e-13 48.0 0.6 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP21239.1 - 2.2e-27 95.3 1.7 5.5e-27 94.0 1.7 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 KFP21239.1 - 5.2e-24 84.5 0.0 2.9e-07 30.8 0.0 5.0 3 1 2 5 5 4 4 HEAT repeats HEAT_EZ PF13513.6 KFP21239.1 - 6.4e-23 80.8 4.7 2.1e-07 31.3 0.0 6.1 4 2 1 5 5 5 4 HEAT-like repeat Arm_3 PF16186.5 KFP21239.1 - 8.9e-23 79.6 3.2 2.9e-22 78.0 2.5 2.3 3 0 0 3 3 3 1 Atypical Arm repeat HEAT PF02985.22 KFP21239.1 - 1.5e-19 68.4 4.6 0.00049 20.1 0.0 8.4 9 0 0 9 9 8 3 HEAT repeat RICTOR_V PF14668.6 KFP21239.1 - 1.2e-06 28.7 0.8 0.19 12.0 0.0 4.7 4 2 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KFP21239.1 - 3.4e-06 27.2 0.0 0.13 12.4 0.0 4.4 3 3 1 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 KFP21239.1 - 1.5e-05 24.6 0.1 0.038 13.4 0.0 3.1 1 1 2 3 3 3 2 Armadillo-like Adaptin_N PF01602.20 KFP21239.1 - 0.00011 20.9 0.0 0.003 16.2 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KFP21239.1 - 0.00035 20.0 0.1 0.27 10.5 0.0 3.6 2 2 1 3 3 3 1 V-ATPase subunit H HEAT_PBS PF03130.16 KFP21239.1 - 0.007 16.9 2.3 6.5 7.7 0.0 5.0 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 KFP21239.1 - 0.0075 15.9 0.0 6.9 6.2 0.0 3.7 1 1 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 KFP21239.1 - 0.018 15.1 0.1 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 KFP21239.1 - 0.046 13.7 0.0 0.99 9.3 0.0 2.7 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CTNNBL PF08216.11 KFP21239.1 - 0.061 13.5 0.0 14 5.9 0.0 3.7 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear NUSAP PF16006.5 KFP21239.1 - 0.22 11.3 4.4 0.29 10.8 4.4 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein DUF1075 PF06388.11 KFP21240.1 - 2.5e-39 134.0 0.3 3.2e-39 133.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) DUF1143 PF06608.11 KFP21240.1 - 0.037 14.1 0.1 0.089 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1143) RFX_DNA_binding PF02257.15 KFP21241.1 - 4e-31 107.5 0.1 1.1e-30 106.1 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KFP21241.1 - 0.099 13.1 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like RAG2_PHD PF13341.6 KFP21241.1 - 0.1 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RAG2 PHD domain Pkinase_Tyr PF07714.17 KFP21242.1 - 1e-96 323.2 0.0 1.9e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 KFP21242.1 - 6.2e-44 148.3 28.2 1.7e-09 37.9 0.4 9.9 9 0 0 9 9 9 9 Fibronectin type III domain Pkinase PF00069.25 KFP21242.1 - 2.2e-41 142.0 0.0 3.6e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3147 PF11345.8 KFP21242.1 - 0.068 13.5 0.7 0.38 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) F5_F8_type_C PF00754.25 KFP21243.1 - 1.5e-26 93.0 2.5 3.5e-26 91.8 2.5 1.6 1 0 0 1 1 1 1 F5/8 type C domain CUB PF00431.20 KFP21243.1 - 3.6e-18 65.9 0.6 9.3e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 CUB domain LCCL PF03815.19 KFP21243.1 - 0.073 13.2 0.5 3.2 7.9 0.5 2.6 1 1 0 1 1 1 0 LCCL domain DUF3377 PF11857.8 KFP21243.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PDZ PF00595.24 KFP21244.1 - 5.6e-17 61.9 1.9 6.2e-17 61.7 0.5 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KFP21244.1 - 7.4e-09 35.3 0.1 1.6e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP21244.1 - 4.6e-05 23.7 0.1 0.00015 22.0 0.1 2.0 1 0 0 1 1 1 1 PDZ domain DUF903 PF06004.12 KFP21244.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) bZIP_2 PF07716.15 KFP21244.1 - 0.018 15.1 7.7 0.018 15.1 7.7 2.7 2 0 0 2 2 2 0 Basic region leucine zipper JAKMIP_CC3 PF16034.5 KFP21244.1 - 0.85 9.5 10.1 0.039 13.9 2.2 2.2 1 1 1 2 2 2 0 JAKMIP CC3 domain DivIC PF04977.15 KFP21244.1 - 1.2 9.0 12.6 1.3 8.9 2.8 2.8 2 0 0 2 2 2 0 Septum formation initiator PRKG1_interact PF15898.5 KFP21244.1 - 4.5 8.2 14.0 1.5 9.8 11.0 1.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 KFP21244.1 - 4.6 6.2 9.7 6.6 5.7 9.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_8 PF13855.6 KFP21245.1 - 7.8e-54 179.3 48.1 8.1e-14 51.1 0.8 7.3 5 3 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KFP21245.1 - 4.8e-32 109.5 51.5 5e-06 26.8 0.9 9.9 2 2 10 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP21245.1 - 7e-12 45.2 24.8 0.00089 18.8 0.6 5.5 1 1 2 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 KFP21245.1 - 8.5e-11 41.9 2.4 1.1e-05 25.4 0.3 4.0 3 2 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP21245.1 - 2.5e-09 36.4 36.7 0.084 13.5 0.1 13.3 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 KFP21245.1 - 8.5e-05 22.3 25.5 0.42 10.8 0.1 9.7 10 0 0 10 10 10 2 Leucine Rich repeat Prenyltransf PF01255.19 KFP21246.1 - 3.2e-08 33.4 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Methyltransf_11 PF08241.12 KFP21246.1 - 0.025 15.2 0.1 0.037 14.7 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFP21246.1 - 0.032 15.0 0.1 0.049 14.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF5099 PF17025.5 KFP21246.1 - 0.045 14.2 0.1 0.15 12.5 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) Methyltransf_25 PF13649.6 KFP21246.1 - 0.06 14.0 0.1 0.093 13.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain SLC35F PF06027.12 KFP21248.1 - 8e-121 403.2 19.3 9.2e-121 403.0 19.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KFP21248.1 - 2.3e-14 53.7 24.2 3.1e-09 37.1 11.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFP21248.1 - 2.6e-09 36.5 7.7 2.6e-09 36.5 7.7 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Mg_trans_NIPA PF05653.14 KFP21248.1 - 0.001 18.3 2.8 0.001 18.3 2.8 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF809 PF05663.11 KFP21248.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF809) DUF812 PF05667.11 KFP21250.1 - 0.0008 18.4 33.1 0.054 12.4 10.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF812) DUF2981 PF11200.8 KFP21250.1 - 0.0035 17.1 1.0 0.0035 17.1 1.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2981) Phospholamban PF04272.14 KFP21251.1 - 4.3e-33 112.5 8.5 4.7e-33 112.4 8.5 1.0 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.11 KFP21251.1 - 0.0063 16.2 4.5 0.01 15.5 4.5 1.4 1 0 0 1 1 1 1 Sarcolipin Anoctamin PF04547.12 KFP21251.1 - 0.12 11.2 0.6 0.11 11.3 0.6 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel MCM PF00493.23 KFP21252.1 - 4.4e-77 258.2 0.0 8.2e-77 257.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFP21252.1 - 9.4e-23 80.4 3.6 3.2e-22 78.7 3.6 1.8 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFP21252.1 - 2.7e-16 59.7 2.2 1.2e-15 57.6 1.9 2.4 3 0 0 3 3 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFP21252.1 - 3.7e-09 36.3 0.1 0.00025 20.5 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFP21252.1 - 2.2e-07 31.0 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFP21252.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFP21252.1 - 0.033 13.9 0.0 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFP21252.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFP21252.1 - 0.046 14.1 0.2 0.59 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 KFP21252.1 - 0.13 11.2 0.6 1.7 7.5 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.6 KFP21252.1 - 0.19 11.4 0.7 0.61 9.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain Rota_NS6 PF04866.12 KFP21252.1 - 2.5 8.4 7.4 13 6.1 0.2 3.4 2 1 1 3 3 3 0 Rotavirus non-structural protein 6 ASF1_hist_chap PF04729.13 KFP21253.1 - 6.7e-72 240.5 0.1 8.3e-72 240.2 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.13 KFP21253.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) Glyco_hydro_47 PF01532.20 KFP21256.1 - 3.7e-154 514.0 0.0 4.2e-154 513.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KFP21256.1 - 0.039 13.0 0.1 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 TBPIP PF07106.13 KFP21256.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain BROMI PF14961.6 KFP21258.1 - 0 2045.0 21.8 0 2044.8 21.8 1.0 1 0 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.18 KFP21258.1 - 0.17 11.5 12.8 0.015 15.0 2.7 3.3 3 0 0 3 3 3 0 Rab-GTPase-TBC domain UBN_AB PF14075.6 KFP21258.1 - 2.6 7.7 5.3 5.7 6.6 0.0 2.7 3 0 0 3 3 3 0 Ubinuclein conserved middle domain Connexin PF00029.19 KFP21260.1 - 8.5e-95 317.0 2.4 1.3e-94 316.4 2.4 1.2 1 0 0 1 1 1 1 Connexin Connexin43 PF03508.13 KFP21260.1 - 4.6e-11 42.0 15.4 1e-10 41.0 15.4 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) Connexin40_C PF16791.5 KFP21260.1 - 4.6e-06 27.8 1.7 7.5e-06 27.2 1.7 1.3 1 0 0 1 1 1 1 Connexin 40 C-terminal domain TEX29 PF15839.5 KFP21260.1 - 4.3 8.0 5.8 1.5 9.5 0.2 2.5 2 1 0 2 2 2 0 Testis-expressed sequence 29 protein Serinc PF03348.15 KFP21263.1 - 1.1e-176 588.0 13.9 1.2e-176 587.8 13.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Lipocalin PF00061.23 KFP21266.1 - 2.9e-21 76.2 1.5 3.2e-21 76.0 1.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP21266.1 - 0.014 15.3 0.3 0.037 13.9 0.2 1.6 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.19 KFP21266.1 - 0.74 9.7 5.0 6.1 6.8 0.1 3.0 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain CRAL_TRIO PF00650.20 KFP21268.1 - 1.2e-34 119.3 0.0 2.3e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KFP21268.1 - 1.7e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFP21268.1 - 2e-06 27.9 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Asp-B-Hydro_N PF05279.11 KFP21269.1 - 8.2e-07 29.3 2.1 8.2e-07 29.3 2.1 2.1 2 0 0 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region DUF4124 PF13511.6 KFP21269.1 - 0.13 12.7 0.0 0.41 11.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) LAP1C PF05609.12 KFP21269.1 - 0.44 9.6 13.1 0.64 9.1 13.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF853 PF05872.12 KFP21269.1 - 2.8 6.4 7.6 3.8 6.0 7.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_13 PF13166.6 KFP21269.1 - 7.3 5.1 18.2 9.7 4.7 18.2 1.0 1 0 0 1 1 1 0 AAA domain NKAIN PF05640.14 KFP21270.1 - 3.6e-24 85.2 2.8 3.8e-24 85.1 2.8 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein IBR PF01485.21 KFP21273.1 - 5.2e-18 65.0 27.5 4.7e-09 36.3 8.3 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-UDP PF14569.6 KFP21273.1 - 7.3 6.8 22.3 7.1 6.8 0.4 3.7 1 1 2 3 3 3 0 Zinc-binding RING-finger TPD52 PF04201.15 KFP21275.1 - 9.2e-62 207.4 5.5 1.2e-61 207.0 5.5 1.2 1 0 0 1 1 1 1 Tumour protein D52 family OST-HTH PF12872.7 KFP21275.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Filament_head PF04732.14 KFP21275.1 - 9.2 7.2 8.6 1.9 9.4 1.5 2.2 1 1 1 2 2 2 0 Intermediate filament head (DNA binding) region HD_3 PF13023.6 KFP21276.1 - 2e-46 157.9 1.8 2.4e-46 157.6 1.8 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFP21276.1 - 3e-16 59.7 0.8 4.3e-16 59.2 0.8 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KFP21276.1 - 0.00023 21.4 0.7 0.00041 20.6 0.7 1.4 1 0 0 1 1 1 1 HD domain DUF4259 PF14078.6 KFP21276.1 - 0.21 12.3 2.8 0.33 11.7 2.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) HLH PF00010.26 KFP21277.1 - 2.5e-18 65.8 3.4 4e-18 65.1 3.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KFP21277.1 - 3.2e-14 52.8 0.1 5.7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange dCache_2 PF08269.11 KFP21277.1 - 0.007 15.6 0.0 0.0074 15.5 0.0 1.1 1 0 0 1 1 1 1 Cache domain DUF3772 PF12607.8 KFP21277.1 - 0.056 13.2 2.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) HTH_Crp_2 PF13545.6 KFP21277.1 - 0.1 12.6 2.5 0.17 11.9 1.3 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TLD PF07534.16 KFP21278.1 - 1.2e-38 132.4 0.6 1.4e-38 132.2 0.6 1.0 1 0 0 1 1 1 1 TLD DcpS_C PF11969.8 KFP21279.1 - 9.5e-27 93.7 0.1 1.1e-26 93.5 0.1 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFP21279.1 - 7.1e-08 33.1 1.0 1e-07 32.6 1.0 1.3 1 1 0 1 1 1 1 HIT domain Costars PF14705.6 KFP21280.1 - 1.3e-33 115.0 0.1 1.6e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Costars UPF0020 PF01170.18 KFP21281.1 - 2.2e-11 43.8 0.0 6.7e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KFP21281.1 - 9.3e-06 25.1 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KFP21281.1 - 0.0047 16.7 0.0 0.51 10.0 0.0 2.4 2 0 0 2 2 2 2 DNA methylase WWE PF02825.20 KFP21284.1 - 3.7e-16 59.5 4.9 6.3e-16 58.7 3.1 2.2 2 0 0 2 2 2 1 WWE domain zf-C3HC4_3 PF13920.6 KFP21284.1 - 3.9e-07 29.8 10.6 7.3e-07 29.0 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP21284.1 - 1.8e-05 24.5 9.4 4.3e-05 23.3 9.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP21284.1 - 0.00014 21.8 9.3 0.00032 20.6 9.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP21284.1 - 0.00016 21.9 12.5 0.00028 21.2 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP21284.1 - 0.00047 19.9 12.0 0.00083 19.1 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP21284.1 - 0.0032 17.3 9.9 0.0061 16.4 9.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFP21284.1 - 0.016 15.4 10.6 0.016 15.4 10.6 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFP21284.1 - 0.016 15.2 11.4 0.029 14.3 11.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 KFP21284.1 - 0.028 14.6 7.4 0.051 13.7 7.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 7tm_1 PF00001.21 KFP21285.1 - 5.5e-24 84.9 4.4 1.7e-22 80.0 0.1 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP21285.1 - 7.1e-07 29.1 11.1 7.1e-07 29.1 11.1 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx HCV_core PF01542.18 KFP21285.1 - 0.029 14.8 0.1 0.061 13.7 0.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus core protein 7tm_4 PF13853.6 KFP21285.1 - 0.079 12.7 5.3 0.83 9.3 1.9 2.1 2 0 0 2 2 2 0 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP21285.1 - 0.1 11.9 10.4 0.054 12.8 6.0 2.3 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srd PF10317.9 KFP21285.1 - 4.9 6.2 14.5 0.26 10.4 8.7 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd CENP-O PF09496.10 KFP21286.1 - 4.8e-12 46.3 3.7 6.1e-12 46.0 0.2 2.1 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Takusan PF04822.13 KFP21286.1 - 0.00032 20.5 0.6 0.0011 18.9 0.5 1.9 2 0 0 2 2 2 1 Takusan Lipocalin_5 PF13924.6 KFP21286.1 - 0.014 15.2 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain Lipoprotein_6 PF01441.19 KFP21286.1 - 0.16 12.0 0.3 0.23 11.5 0.3 1.2 1 0 0 1 1 1 0 Lipoprotein DivIC PF04977.15 KFP21286.1 - 0.17 11.7 6.1 0.42 10.4 6.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 KFP21286.1 - 3.1 8.3 5.9 6 7.4 5.9 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ras PF00071.22 KFP21287.1 - 1.1e-36 125.8 0.1 1.4e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21287.1 - 6.5e-19 68.3 0.0 4.2e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DnaJ PF00226.31 KFP21287.1 - 3.4e-12 46.3 0.0 6.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Arf PF00025.21 KFP21287.1 - 3.8e-12 46.0 0.0 4.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP21287.1 - 0.0004 20.0 0.1 0.00097 18.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Fibrinogen_C PF00147.18 KFP21289.1 - 2.4e-43 148.5 0.4 2.7e-43 148.3 0.4 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain NYD-SP28 PF14772.6 KFP21291.1 - 1.5e-28 98.8 19.5 1.5e-28 98.8 19.5 4.9 3 1 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 KFP21291.1 - 1.6e-07 31.3 0.1 1.6e-07 31.3 0.1 5.3 2 1 3 5 5 5 1 Sperm tail C-terminal domain rve PF00665.26 KFP21292.1 - 7.3e-24 84.2 0.1 1.2e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.19 KFP21292.1 - 8.3e-12 44.9 1.0 2.3e-11 43.5 1.0 1.8 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.24 KFP21292.1 - 0.00058 20.1 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 RNase H rve_3 PF13683.6 KFP21292.1 - 0.0069 16.1 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KFP21292.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 DDE domain Neur_chan_memb PF02932.16 KFP21294.1 - 1.2e-89 300.5 15.5 2.2e-64 217.8 12.2 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP21294.1 - 6.8e-79 264.3 3.6 8.5e-79 264.0 3.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Glycoprotein PF03409.15 KFP21294.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein DUF2417 PF10329.9 KFP21294.1 - 1.6 8.1 11.6 0.25 10.7 7.6 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) SRCR PF00530.18 KFP21295.1 - 1.1e-15 58.0 0.3 2.6e-15 56.7 0.3 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Collagen PF01391.18 KFP21295.1 - 9.5e-14 50.9 54.3 5.4e-09 35.7 22.9 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SRCR_2 PF15494.6 KFP21295.1 - 8.5e-06 26.2 0.9 2.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF3450 PF11932.8 KFP21295.1 - 0.0073 15.6 0.4 0.014 14.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) OppC_N PF12911.7 KFP21295.1 - 0.034 14.1 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Pep_M12B_propep PF01562.19 KFP21295.1 - 0.089 13.0 2.7 0.93 9.7 0.3 2.3 2 0 0 2 2 2 0 Reprolysin family propeptide Fib_alpha PF08702.10 KFP21295.1 - 0.46 10.7 5.8 0.72 10.0 0.6 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 KFP21296.1 - 4.8e-37 127.8 0.0 6.2e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21296.1 - 2.3e-32 112.3 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFP21296.1 - 0.049 13.2 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFP21296.1 - 0.05 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH_6_hur PF04655.14 KFP21296.1 - 0.19 11.1 0.0 1.8 7.9 0.0 1.9 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Acetyltransf_13 PF13880.6 KFP21297.1 - 6.7e-29 99.7 0.0 1.2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KFP21297.1 - 1.1e-16 60.4 0.5 3e-16 59.0 0.5 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO NFACT-R_1 PF05670.13 KFP21298.1 - 4.8e-43 146.3 0.0 5.1e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain YscJ_FliF PF01514.17 KFP21298.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family SEA PF01390.20 KFP21299.1 - 1.5e-124 407.7 18.8 8.9e-24 83.6 0.3 6.1 6 0 0 6 6 6 6 SEA domain SH3_10 PF17902.1 KFP21299.1 - 0.00021 21.3 0.0 13 5.9 0.0 4.3 4 0 0 4 4 4 1 SH3 domain Epiglycanin_C PF14654.6 KFP21299.1 - 0.013 15.6 0.2 0.029 14.4 0.2 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region UPF0560 PF10577.9 KFP21299.1 - 0.04 12.4 1.9 0.067 11.7 1.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2205 PF10224.9 KFP21299.1 - 0.073 13.1 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Phage_DNA_bind PF02303.17 KFP21299.1 - 0.86 9.9 2.5 22 5.4 0.0 3.7 5 0 0 5 5 5 0 Helix-destabilising protein Pkinase_Tyr PF07714.17 KFP21300.1 - 1.4e-91 306.4 1.3 1.8e-91 306.0 1.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP21300.1 - 4.9e-48 163.8 0.4 7.5e-48 163.2 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP21300.1 - 8.4e-42 141.1 0.1 2.7e-22 78.6 0.1 2.6 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 KFP21300.1 - 0.00027 20.0 0.2 0.00056 19.0 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KFP21300.1 - 0.00069 19.3 2.0 0.0011 18.5 2.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP21300.1 - 0.024 14.0 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GrlR PF16518.5 KFP21300.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 T3SS negative regulator,GrlR Pep_M12B_propep PF01562.19 KFP21301.1 - 1.4e-37 129.1 0.1 2.2e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFP21301.1 - 2.6e-32 111.2 0.0 4.4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 KFP21301.1 - 1.5e-17 63.8 9.1 1.5e-17 63.8 9.1 5.6 5 1 0 5 5 5 2 ADAM cysteine-rich domain TSP_1 PF00090.19 KFP21301.1 - 6.7e-16 58.2 89.3 5.6e-07 29.7 8.2 7.9 8 1 0 8 8 8 5 Thrombospondin type 1 domain Reprolysin PF01421.19 KFP21301.1 - 3.1e-12 46.8 1.3 1.6e-11 44.5 1.3 2.2 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.11 KFP21301.1 - 3.1e-09 37.4 11.6 1.6e-08 35.1 11.6 2.4 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain MBOAT PF03062.19 KFP21302.1 - 2.3e-53 181.8 34.1 3.5e-53 181.2 34.1 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family COX2_TM PF02790.15 KFP21302.1 - 0.33 11.1 7.4 13 6.0 0.1 3.5 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Ax_dynein_light PF10211.9 KFP21303.1 - 7.2e-10 39.1 13.5 4.5e-09 36.5 9.5 2.3 2 0 0 2 2 2 1 Axonemal dynein light chain DUF5092 PF17010.5 KFP21303.1 - 0.13 12.2 0.5 0.22 11.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5092) Fib_alpha PF08702.10 KFP21303.1 - 0.8 9.9 7.1 0.76 10.0 2.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KFP21303.1 - 2.2 8.9 8.1 22 5.7 4.7 2.9 2 1 0 2 2 2 0 Initiation control protein YabA TetR_C_11 PF16859.5 KFP21303.1 - 2.3 8.6 8.5 1.2 9.5 1.3 3.3 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Band_7 PF01145.25 KFP21304.1 - 1e-25 90.8 0.0 1.8e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KFP21304.1 - 0.0078 15.9 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family OST-HTH PF12872.7 KFP21305.1 - 1.5e-05 24.7 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain TUDOR PF00567.24 KFP21306.1 - 2.7e-13 50.0 0.2 6.5e-13 48.8 0.1 1.7 2 0 0 2 2 2 1 Tudor domain FAM163 PF15069.6 KFP21307.1 - 5.8e-72 241.5 0.5 6.5e-72 241.3 0.5 1.0 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.6 KFP21307.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF4006) EphA2_TM PF14575.6 KFP21307.1 - 0.033 15.1 0.0 0.043 14.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 KFP21307.1 - 0.033 13.9 0.3 0.045 13.4 0.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF3169 PF11368.8 KFP21307.1 - 0.033 13.7 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MscL PF01741.18 KFP21307.1 - 0.053 13.8 0.0 0.068 13.5 0.0 1.1 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL PRIMA1 PF16101.5 KFP21307.1 - 3.4 7.7 6.3 0.65 10.0 0.1 2.3 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 HCV_NS4a PF01006.20 KFP21307.1 - 5.7 6.8 8.0 3.6 7.4 3.2 2.5 2 1 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a TSP_1 PF00090.19 KFP21308.1 - 7.3e-27 93.3 119.7 2e-06 27.9 13.2 9.3 8 1 0 8 8 8 7 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP21308.1 - 6.9e-25 87.3 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.11 KFP21308.1 - 6.3e-10 39.6 10.8 6.3e-10 39.6 10.8 2.9 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain GYR PF02756.14 KFP21308.1 - 0.26 11.1 1.8 0.57 9.9 1.8 1.6 1 0 0 1 1 1 0 GYR motif LAP1C PF05609.12 KFP21309.1 - 4.2e-98 329.4 0.1 4.6e-98 329.3 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) LAP1C PF05609.12 KFP21310.1 - 1.3e-104 350.9 0.1 1.4e-104 350.7 0.1 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Stap_Strp_tox_C PF02876.17 KFP21310.1 - 0.03 14.6 0.0 0.074 13.4 0.0 1.6 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain CAP_GLY PF01302.25 KFP21311.1 - 1.5e-20 73.0 0.2 2.5e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF4378 PF14309.6 KFP21311.1 - 7.3e-06 26.4 4.0 1.4e-05 25.5 0.9 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4378) Glyco_hydro_92 PF07971.12 KFP21311.1 - 0.37 9.7 3.8 0.22 10.4 0.1 2.4 3 0 0 3 3 3 0 Glycosyl hydrolase family 92 QSOX_Trx1 PF18108.1 KFP21312.1 - 6.9e-45 151.7 0.0 3e-44 149.6 0.0 2.1 3 0 0 3 3 3 1 QSOX Trx-like domain FAD_SOX PF18371.1 KFP21312.1 - 7.7e-43 145.1 0.0 1.9e-42 143.8 0.0 1.7 1 0 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Evr1_Alr PF04777.13 KFP21312.1 - 2.2e-25 89.0 0.1 4.6e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 KFP21312.1 - 0.00029 20.8 0.0 0.0043 17.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KFP21312.1 - 0.0032 17.9 0.0 15 6.0 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Zn-ribbon_8 PF09723.10 KFP21312.1 - 0.92 9.7 4.7 15 5.8 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain LIM PF00412.22 KFP21313.1 - 2.4e-32 110.9 19.5 1.1e-16 60.8 2.9 2.2 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFP21313.1 - 1.7e-21 75.8 2.4 2.8e-21 75.1 2.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP21313.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.7 1 1 0 1 1 1 1 Homeobox KN domain Furin-like_2 PF15913.5 KFP21313.1 - 0.0043 17.2 7.1 0.0043 17.2 7.1 2.1 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich PHF5 PF03660.14 KFP21313.1 - 1.8 8.8 10.2 0.094 12.9 3.3 2.1 1 1 1 2 2 2 0 PHF5-like protein Ank_4 PF13637.6 KFP21314.1 - 7.2e-20 71.1 1.3 3.2e-14 53.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP21314.1 - 1.1e-16 61.2 0.1 1.9e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP21314.1 - 1.9e-15 56.5 0.1 8.1e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFP21314.1 - 2.9e-15 56.1 0.1 1.8e-10 40.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ACBP PF00887.19 KFP21314.1 - 8e-15 54.8 0.1 1.4e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_3 PF13606.6 KFP21314.1 - 6.3e-14 50.7 0.3 5.6e-05 23.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat GhoS PF11080.8 KFP21314.1 - 0.14 12.2 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Endoribonuclease GhoS GBP_repeat PF02526.14 KFP21314.1 - 0.14 11.9 0.0 6.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Glycophorin-binding protein EXS PF03124.14 KFP21315.1 - 6.7e-107 357.6 24.7 8.9e-107 357.2 24.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KFP21315.1 - 6.1e-21 75.8 15.2 4.5e-14 53.2 5.5 2.2 1 1 1 2 2 2 2 SPX domain Syntaxin-6_N PF09177.11 KFP21316.1 - 1.4e-30 105.7 1.0 1.4e-30 105.7 1.0 2.8 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KFP21316.1 - 1.9e-13 50.2 1.8 4.9e-13 48.9 1.8 1.8 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 KFP21316.1 - 0.0081 14.2 4.9 0.03 12.3 4.8 1.8 1 1 0 1 1 1 1 Prominin UPF0184 PF03670.13 KFP21316.1 - 0.029 14.7 0.2 0.73 10.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) FliD_C PF07195.12 KFP21316.1 - 0.05 13.0 4.0 2.6 7.4 0.0 2.7 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Pox_EPC_I2-L1 PF12575.8 KFP21316.1 - 0.077 13.2 1.1 0.19 12.0 1.1 1.7 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Use1 PF09753.9 KFP21316.1 - 0.12 12.0 6.8 0.27 10.9 6.8 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 APG17 PF04108.12 KFP21316.1 - 0.14 11.2 10.9 0.064 12.4 2.3 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF1664 PF07889.12 KFP21316.1 - 0.5 10.4 7.0 11 6.1 2.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KFP21316.1 - 2.4 8.1 5.6 0.9 9.5 2.1 2.2 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Exonuc_VII_L PF02601.15 KFP21316.1 - 2.7 7.5 9.4 7 6.1 9.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KFP21316.1 - 6.1 7.2 9.1 2.4 8.5 3.1 2.8 3 1 0 3 3 3 0 Uncharacterized conserved protein zf-H2C2_2 PF13465.6 KFP21318.1 - 3.5e-37 125.2 44.0 5.8e-07 29.7 2.8 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KFP21318.1 - 4.7e-30 102.3 39.3 5.3e-05 23.5 3.1 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21318.1 - 1.6e-22 78.2 39.4 0.00085 20.0 2.2 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP21318.1 - 3e-13 49.6 14.7 0.12 12.6 0.1 7.2 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KFP21318.1 - 4.2e-10 39.7 10.1 0.058 13.7 0.0 6.2 6 0 0 6 6 6 2 zinc-ribbon Zn-ribbon_8 PF09723.10 KFP21318.1 - 6e-09 35.9 23.4 0.017 15.2 1.0 5.6 4 1 2 6 6 6 4 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP21318.1 - 4.7e-08 32.6 23.9 0.025 14.3 1.1 6.0 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFP21318.1 - 3.2e-07 30.2 40.1 0.033 14.2 0.2 7.6 7 1 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 KFP21318.1 - 1.3e-05 25.4 6.1 0.00049 20.3 0.7 4.8 2 2 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 KFP21318.1 - 1.8e-05 24.6 15.9 0.27 11.1 0.1 6.0 6 0 0 6 6 6 1 Probable zinc-ribbon domain zf_UBZ PF18439.1 KFP21318.1 - 5.4e-05 22.7 18.3 6.5 6.4 0.0 7.1 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFP21318.1 - 0.00032 21.4 17.4 0.11 13.2 1.0 5.0 1 1 3 4 4 4 1 Zinc finger C2H2-type, 3 repeats C1_1 PF00130.22 KFP21318.1 - 0.00045 20.1 19.2 0.55 10.2 0.3 5.4 3 2 4 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 KFP21318.1 - 0.0023 18.0 12.9 0.51 10.4 0.6 3.4 2 1 1 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 KFP21318.1 - 0.0045 17.4 26.7 0.24 11.9 5.1 5.8 1 1 4 5 5 5 1 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 KFP21318.1 - 0.0088 16.3 20.0 1.6 9.0 3.1 4.9 1 1 5 6 6 6 1 TFIIH C1-like domain Zn_ribbon_recom PF13408.6 KFP21318.1 - 0.013 16.0 18.6 1.4 9.5 0.6 5.1 3 1 2 5 5 5 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 KFP21318.1 - 0.02 14.9 17.8 10 6.2 1.6 5.1 1 1 2 3 3 3 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 KFP21318.1 - 0.02 14.8 22.5 2.4 8.1 0.2 5.0 2 1 3 5 5 5 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KFP21318.1 - 0.068 13.9 16.3 2.1 9.2 0.3 4.0 1 1 3 4 4 4 0 zinc-ribbon family FYVE PF01363.21 KFP21318.1 - 0.076 13.2 23.0 4.7 7.4 3.0 5.1 1 1 4 5 5 5 0 FYVE zinc finger zf-AN1 PF01428.16 KFP21318.1 - 0.076 13.2 27.3 13 6.1 1.3 6.4 5 1 1 6 6 6 0 AN1-like Zinc finger Evr1_Alr PF04777.13 KFP21318.1 - 0.14 12.6 16.5 9.3 6.8 2.5 5.1 1 1 2 3 3 3 0 Erv1 / Alr family XPA_N PF01286.18 KFP21318.1 - 0.15 12.1 21.4 20 5.3 0.1 6.6 7 0 0 7 7 7 0 XPA protein N-terminal BolA PF01722.18 KFP21318.1 - 0.2 12.0 6.6 8.5 6.7 0.1 3.9 2 2 2 4 4 4 0 BolA-like protein zf-RING_7 PF02591.15 KFP21318.1 - 0.29 11.3 14.6 13 6.1 0.1 5.5 6 0 0 6 6 6 0 C4-type zinc ribbon domain zf-met PF12874.7 KFP21318.1 - 0.31 11.5 23.8 1.2 9.7 0.0 6.2 7 0 0 7 7 6 0 Zinc-finger of C2H2 type Fer4_10 PF13237.6 KFP21318.1 - 0.39 10.9 11.3 19 5.5 3.8 4.5 4 1 0 4 4 4 0 4Fe-4S dicluster domain Ribosomal_L37ae PF01780.19 KFP21318.1 - 0.55 10.3 21.4 2.3 8.3 0.1 5.5 2 2 3 5 5 5 0 Ribosomal L37ae protein family PyrI_C PF02748.15 KFP21318.1 - 0.65 10.0 0.1 0.65 10.0 0.1 4.4 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2225 PF09986.9 KFP21318.1 - 0.79 9.4 12.1 5.4 6.7 2.1 4.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Rad50_zn_hook PF04423.14 KFP21318.1 - 0.81 9.6 5.8 2 8.4 0.0 3.6 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 KFP21318.1 - 1.3 9.4 19.0 8.1 6.9 0.3 5.5 1 1 2 4 4 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KFP21318.1 - 1.8 8.4 12.2 12 5.8 0.1 4.3 1 1 3 5 5 5 0 GAGA factor CpXC PF14353.6 KFP21318.1 - 2.2 8.4 18.4 20 5.3 0.1 5.6 1 1 4 6 6 6 0 CpXC protein ADK_lid PF05191.14 KFP21318.1 - 2.8 8.0 18.0 1.3 9.1 1.3 4.7 3 2 1 4 4 4 0 Adenylate kinase, active site lid DUF3268 PF11672.8 KFP21318.1 - 4.3 7.7 13.4 19 5.6 0.7 3.6 1 1 2 4 4 4 0 zinc-finger-containing domain OrfB_Zn_ribbon PF07282.11 KFP21318.1 - 4.4 7.3 23.1 17 5.5 0.3 5.3 3 1 3 6 6 6 0 Putative transposase DNA-binding domain zf-C2H2_9 PF16293.5 KFP21318.1 - 4.5 7.2 10.4 16 5.4 0.2 4.4 4 2 3 7 7 4 0 C2H2 type zinc-finger (1 copy) Ribosomal_L44 PF00935.19 KFP21318.1 - 7.3 7.2 18.5 0.093 13.2 1.7 4.1 3 1 1 5 5 5 0 Ribosomal protein L44 zf-ribbon_3 PF13248.6 KFP21318.1 - 7.3 6.2 24.6 2.1 7.9 0.1 6.1 7 0 0 7 7 6 0 zinc-ribbon domain Cytochrom_CIII PF02085.16 KFP21318.1 - 7.5 7.0 23.1 4.4 7.7 4.6 3.4 1 1 2 3 3 3 0 Class III cytochrome C family Gln-synt_C PF00120.24 KFP21319.1 - 1.2e-17 64.0 0.0 1.5e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFP21319.1 - 2.5e-14 52.8 0.0 4.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain F-box-like PF12937.7 KFP21319.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like RGS PF00615.19 KFP21320.1 - 5.6e-09 36.3 1.6 0.00017 21.9 0.1 3.3 4 0 0 4 4 4 2 Regulator of G protein signaling domain Meleagrin PF08189.11 KFP21320.1 - 0.66 9.7 3.0 5.4 6.8 0.1 2.7 2 0 0 2 2 2 0 Meleagrin/Cygnin family Ank_2 PF12796.7 KFP21322.1 - 9.1e-44 148.0 4.9 4.1e-14 52.9 0.1 5.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP21322.1 - 1.2e-37 127.8 2.6 9.9e-09 35.6 0.0 7.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP21322.1 - 6.9e-32 105.9 0.2 0.0081 16.6 0.0 8.7 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KFP21322.1 - 1.4e-30 105.0 2.2 1.1e-05 25.6 0.0 6.0 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP21322.1 - 1.5e-28 98.0 1.7 0.0024 18.2 0.0 8.6 8 0 0 8 8 8 5 Ankyrin repeat Ribonuc_2-5A PF06479.12 KFP21322.1 - 1.2e-11 44.8 0.4 4.7e-11 42.9 0.4 2.0 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KFP21322.1 - 3.8e-11 42.9 0.0 1.2e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KFP21322.1 - 5.5e-07 29.1 0.3 2.1e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFP21322.1 - 0.0035 16.7 0.0 0.0079 15.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase BAR_3 PF16746.5 KFP21322.1 - 0.041 13.6 0.0 5.4 6.6 0.0 2.4 2 0 0 2 2 2 0 BAR domain of APPL family APH PF01636.23 KFP21322.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP21322.1 - 0.075 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RGS PF00615.19 KFP21323.1 - 9.4e-37 125.9 3.6 1.2e-36 125.6 3.6 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain tRNA-synt_2 PF00152.20 KFP21324.1 - 7.3e-96 320.9 0.0 8.9e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 KFP21324.1 - 2e-12 47.2 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 KFP21324.1 - 5.2e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CENP-L PF13092.6 KFP21325.1 - 5.7e-33 114.4 0.1 8.3e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Kelch_1 PF01344.25 KFP21326.1 - 3e-92 302.0 20.9 3.5e-17 61.7 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP21326.1 - 1.1e-53 177.8 7.3 1.9e-09 37.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 KFP21326.1 - 2.5e-38 130.3 0.5 4.3e-38 129.6 0.1 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP21326.1 - 1.2e-35 121.2 7.1 1.5e-05 24.9 0.0 6.2 2 2 4 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KFP21326.1 - 9.2e-33 112.8 0.7 1.5e-32 112.1 0.3 1.6 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 KFP21326.1 - 7.2e-32 108.2 6.4 1.2e-06 28.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFP21326.1 - 1.1e-30 105.3 16.2 9.4e-06 25.8 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP21326.1 - 8e-06 25.7 8.6 2 8.5 0.1 5.9 6 0 0 6 6 6 3 Kelch motif XPA_C PF05181.12 KFP21326.1 - 0.033 14.2 0.4 5.5 7.0 0.0 3.3 4 0 0 4 4 4 0 XPA protein C-terminus Glu_cyclase_2 PF05096.12 KFP21326.1 - 0.075 12.4 0.0 29 4.0 0.0 2.7 1 1 0 3 3 3 0 Glutamine cyclotransferase PQQ_3 PF13570.6 KFP21326.1 - 5 7.7 16.7 1.1 9.9 0.5 4.8 5 0 0 5 5 5 0 PQQ-like domain PRK PF00485.18 KFP21327.1 - 9.4e-47 159.3 0.8 1.1e-46 159.1 0.8 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF826 PF05696.11 KFP21327.1 - 0.1 12.7 0.0 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF826) EMC3_TMCO1 PF01956.16 KFP21328.1 - 2.5e-38 131.5 1.2 2.8e-38 131.3 1.2 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TRAM1 PF08390.11 KFP21328.1 - 0.0028 17.3 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 TRAM1-like protein DUF2368 PF10166.9 KFP21328.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DivIC PF04977.15 KFP21328.1 - 0.067 13.0 0.4 0.067 13.0 0.4 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4257 PF14074.6 KFP21328.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF1090 PF06476.12 KFP21328.1 - 0.7 10.0 12.9 1.2 9.2 12.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) XhlA PF10779.9 KFP21328.1 - 0.92 9.8 6.5 5.5 7.3 6.5 2.1 1 1 0 1 1 1 0 Haemolysin XhlA Atg14 PF10186.9 KFP21328.1 - 1.8 7.6 6.6 2.4 7.1 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Aldedh PF00171.22 KFP21329.1 - 1.1e-168 561.6 0.0 1.2e-168 561.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAPEG PF01124.18 KFP21330.1 - 5.4e-22 78.1 0.9 6.7e-22 77.8 0.9 1.1 1 0 0 1 1 1 1 MAPEG family LRR_8 PF13855.6 KFP21331.1 - 6.5e-21 73.9 20.5 2.4e-10 40.0 2.5 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFP21331.1 - 2e-07 31.2 10.4 0.0069 16.8 2.1 3.5 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KFP21331.1 - 6.4e-05 22.5 0.8 6.4e-05 22.5 0.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP21331.1 - 0.0055 16.7 8.3 1.7 8.9 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_5 PF13306.6 KFP21331.1 - 0.022 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP21331.1 - 0.024 15.1 10.7 0.32 11.7 0.1 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat Nuf2 PF03800.14 KFP21332.1 - 1e-29 103.4 0.1 1e-29 103.4 0.1 2.7 3 1 0 3 3 3 1 Nuf2 family Filament PF00038.21 KFP21332.1 - 0.0028 17.3 50.1 0.027 14.1 17.9 3.5 1 1 3 4 4 4 2 Intermediate filament protein Topoisom_I PF01028.20 KFP21332.1 - 0.014 14.6 1.6 0.014 14.6 1.6 3.9 1 1 2 4 4 4 0 Eukaryotic DNA topoisomerase I, catalytic core DUF5644 PF18712.1 KFP21332.1 - 0.065 13.2 1.6 0.25 11.4 0.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5644) G-gamma PF00631.22 KFP21332.1 - 0.066 13.2 4.8 0.073 13.1 0.1 3.1 2 0 0 2 2 2 0 GGL domain HMMR_N PF15905.5 KFP21332.1 - 0.14 11.6 59.4 0.54 9.7 22.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SAVED PF18145.1 KFP21332.1 - 0.37 10.6 3.8 1.6 8.5 0.1 2.7 2 1 0 3 3 3 0 SMODS-associated and fused to various effectors sensor domain Atg14 PF10186.9 KFP21332.1 - 0.46 9.5 49.4 0.95 8.5 19.5 2.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KFP21332.1 - 2.2 8.1 41.3 2.4 7.9 18.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) LPP PF04728.13 KFP21332.1 - 2.4 8.6 13.0 4.2 7.8 0.1 4.5 4 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF3584 PF12128.8 KFP21332.1 - 3.2 5.1 48.9 1 6.8 29.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Complex1_49kDa PF00346.19 KFP21332.1 - 5.9 5.9 10.9 0.24 10.5 1.4 2.8 3 0 0 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit ATG16 PF08614.11 KFP21332.1 - 6.2 7.0 49.5 0.075 13.3 27.4 3.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PBC PF03792.13 KFP21333.1 - 3.3e-67 225.9 0.3 5.3e-67 225.3 0.0 1.5 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 KFP21333.1 - 9.1e-20 70.3 0.9 2.1e-19 69.1 0.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP21333.1 - 4.7e-16 58.4 0.0 1.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KFP21333.1 - 0.0021 17.9 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KFP21333.1 - 0.0091 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix Sec15 PF04091.12 KFP21333.1 - 0.01 15.2 0.5 0.016 14.7 0.5 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like LZ3wCH PF18517.1 KFP21333.1 - 0.16 12.1 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain NUC130_3NT PF08158.12 KFP21333.1 - 0.49 10.8 1.6 27 5.2 0.1 3.0 3 0 0 3 3 3 0 NUC130/3NT domain LIM PF00412.22 KFP21334.1 - 2.3e-31 107.8 24.1 3.9e-16 59.0 8.0 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KFP21334.1 - 4.4e-18 64.9 2.5 7.8e-18 64.1 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP21334.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Nuc_recep-AF1 PF11825.8 KFP21335.1 - 9.2e-45 151.4 15.1 1.8e-44 150.4 15.1 1.5 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 Hormone_recep PF00104.30 KFP21335.1 - 2.2e-38 131.9 0.0 4.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP21335.1 - 4.6e-32 110.3 15.8 7.9e-32 109.5 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Ocnus PF05005.15 KFP21336.1 - 3.1e-24 85.2 0.4 3.4e-24 85.0 0.4 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Methyltransf_16 PF10294.9 KFP21337.1 - 3.4e-12 46.4 0.0 5.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KFP21337.1 - 3.1e-06 27.1 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP21337.1 - 9.7e-06 25.5 0.0 0.089 12.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KFP21337.1 - 1.7e-05 24.4 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFP21337.1 - 7.5e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFP21337.1 - 0.0004 21.1 0.0 1 10.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Cons_hypoth95 PF03602.15 KFP21337.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KFP21337.1 - 0.0097 16.6 0.0 0.099 13.4 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFP21337.1 - 0.041 13.1 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family AbiJ_NTD5 PF18865.1 KFP21337.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF4487 PF14868.6 KFP21338.1 - 3.2e-189 630.3 30.3 3.2e-189 630.3 30.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4487) Pkinase PF00069.25 KFP21339.1 - 6e-06 25.8 0.0 0.00011 21.6 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Methyltransf_PK PF05891.12 KFP21340.1 - 1.6e-68 230.5 0.0 2.1e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KFP21340.1 - 1.8e-06 28.5 0.0 3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP21340.1 - 3.7e-05 24.3 0.0 6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP21340.1 - 0.00049 20.8 0.0 0.00084 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFP21340.1 - 0.0047 16.3 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Transcrip_act PF04949.13 KFP21341.1 - 5.8e-08 32.8 18.5 1.5e-07 31.4 18.5 1.7 1 1 0 1 1 1 1 Transcriptional activator Homeodomain PF00046.29 KFP21342.1 - 3.4e-23 81.2 6.4 6.3e-23 80.4 6.4 1.5 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP21342.1 - 4.7e-08 32.6 0.1 9.1e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP21342.1 - 0.00049 19.9 0.2 0.0014 18.4 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain FMO-like PF00743.19 KFP21343.1 - 2.4e-260 864.4 0.0 2.7e-260 864.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP21343.1 - 4.5e-18 65.5 0.0 1.1e-13 51.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP21343.1 - 1.1e-12 47.9 0.0 2.2e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP21343.1 - 6.1e-10 38.8 0.2 8.9e-07 28.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP21343.1 - 1e-05 25.6 0.0 3.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFP21343.1 - 2.8e-05 24.6 0.1 0.029 14.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFP21343.1 - 0.00013 21.7 0.8 1.2 8.6 0.0 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFP21343.1 - 0.00073 19.6 0.4 0.63 10.0 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFP21343.1 - 0.037 13.3 0.2 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFP21343.1 - 0.051 12.9 0.1 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KFP21343.1 - 0.069 12.4 0.0 0.78 8.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KFP21343.1 - 0.23 10.5 0.3 0.78 8.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain FMO-like PF00743.19 KFP21344.1 - 1.4e-242 805.8 0.0 1.6e-242 805.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP21344.1 - 2e-18 66.7 0.0 1.8e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP21344.1 - 7e-14 51.7 0.0 7.4e-11 41.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP21344.1 - 1.6e-09 37.4 0.0 4.9e-08 32.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFP21344.1 - 4e-07 29.9 0.8 0.002 17.8 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP21344.1 - 2.9e-06 27.4 0.3 9.4e-06 25.8 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFP21344.1 - 3.9e-06 27.3 1.0 0.0023 18.4 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFP21344.1 - 0.0057 16.7 0.3 0.64 10.0 0.0 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFP21344.1 - 0.0062 15.8 0.1 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KFP21344.1 - 0.0096 15.2 0.5 2.8 7.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFP21344.1 - 0.1 11.7 2.6 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFP21344.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KFP21344.1 - 0.16 11.3 3.6 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KFP21344.1 - 0.42 9.6 1.9 3.7 6.5 0.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFP21344.1 - 0.5 9.0 1.9 2.8 6.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FMO-like PF00743.19 KFP21345.1 - 2.3e-235 782.1 0.0 2.6e-235 781.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP21345.1 - 1.9e-17 63.5 0.0 5.5e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP21345.1 - 1.7e-11 43.9 0.0 1.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP21345.1 - 2.7e-07 30.1 0.0 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP21345.1 - 0.00011 22.3 0.0 0.0004 20.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFP21345.1 - 0.0003 20.8 0.0 0.0015 18.5 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFP21345.1 - 0.0013 18.4 0.1 0.14 11.7 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFP21345.1 - 0.0026 18.3 0.2 1.4 9.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KFP21345.1 - 0.1 11.9 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OLF PF02191.16 KFP21346.1 - 2e-82 276.5 0.0 2.3e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Synaptobrevin PF00957.21 KFP21347.1 - 1.3e-34 117.8 2.9 1.6e-34 117.6 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFP21347.1 - 0.00095 19.3 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 KFP21347.1 - 0.0053 16.3 0.7 0.0075 15.8 0.7 1.2 1 0 0 1 1 1 1 fzo-like conserved region DUF1035 PF06281.12 KFP21347.1 - 0.027 14.5 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) NPV_P10 PF05531.12 KFP21347.1 - 0.035 14.6 0.3 0.054 14.0 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF5345 PF17280.2 KFP21347.1 - 0.047 13.7 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) UPF0258 PF06789.12 KFP21347.1 - 0.049 13.8 0.7 0.07 13.3 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Ferlin_C PF16165.5 KFP21347.1 - 0.087 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus DUF948 PF06103.11 KFP21347.1 - 3.2 8.1 9.1 0.4 11.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KFP21347.1 - 3.7 7.6 8.5 0.94 9.5 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GP41 PF00517.17 KFP21347.1 - 7.9 6.3 10.2 0.29 11.0 1.1 1.9 1 1 1 2 2 2 0 Retroviral envelope protein Ham1p_like PF01725.16 KFP21348.1 - 3.6e-42 144.4 0.0 4e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_25 PF13649.6 KFP21349.1 - 1.6e-18 67.2 0.1 4.4e-12 46.5 0.1 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KFP21349.1 - 8.2e-18 64.7 0.0 1.1e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFP21349.1 - 5.8e-17 62.1 0.4 3.3e-13 50.1 0.0 3.2 2 1 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.17 KFP21349.1 - 3.6e-10 39.6 0.5 1.2e-08 34.7 0.0 2.3 2 1 0 2 2 2 1 Spermine/spermidine synthase domain MTS PF05175.14 KFP21349.1 - 1.8e-05 24.3 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 KFP21349.1 - 2.1e-05 25.2 0.0 0.0051 17.5 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP21349.1 - 9.4e-05 22.3 0.0 0.047 13.5 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KFP21349.1 - 0.00034 20.0 0.2 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Dynamin_M PF01031.20 KFP21350.1 - 5.8e-103 344.0 3.8 5.8e-103 344.0 3.8 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFP21350.1 - 7.3e-43 146.5 0.0 2.4e-42 144.9 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFP21350.1 - 7.1e-28 96.6 4.8 7.1e-28 96.6 4.8 2.9 3 0 0 3 3 3 1 Dynamin GTPase effector domain PH PF00169.29 KFP21350.1 - 1.4e-13 51.2 0.7 3.4e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP21350.1 - 0.1 13.0 1.5 0.62 10.5 1.5 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain DASH_Duo1 PF08651.10 KFP21350.1 - 0.11 12.3 0.1 9.3 6.1 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 GPI2 PF06432.11 KFP21351.1 - 9.7e-57 192.5 2.0 1.1e-56 192.4 2.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Sad1_UNC PF07738.13 KFP21352.1 - 3.8e-37 127.3 0.0 9.3e-37 126.0 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal dNK PF01712.19 KFP21352.1 - 0.012 15.5 0.7 0.033 14.1 0.7 1.7 1 0 0 1 1 1 0 Deoxynucleoside kinase MbeD_MobD PF04899.12 KFP21352.1 - 0.04 14.0 6.5 0.12 12.5 6.5 1.8 1 0 0 1 1 1 0 MbeD/MobD like Tweety PF04906.13 KFP21352.1 - 0.062 12.0 4.5 0.11 11.2 4.5 1.2 1 0 0 1 1 1 0 Tweety TraH_2 PF06871.11 KFP21352.1 - 0.1 12.3 0.3 0.27 10.8 0.3 1.7 1 0 0 1 1 1 0 TraH_2 DUF3169 PF11368.8 KFP21352.1 - 0.36 10.3 2.1 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Telomere_reg-2 PF10193.9 KFP21352.1 - 0.55 10.7 3.6 2.1 8.8 3.6 2.0 1 0 0 1 1 1 0 Telomere length regulation protein SlyX PF04102.12 KFP21352.1 - 1.2 9.8 11.9 3.3 8.4 3.8 3.0 1 1 1 2 2 2 0 SlyX Baculo_PEP_C PF04513.12 KFP21352.1 - 3.2 7.8 12.6 0.11 12.6 6.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TNF PF00229.18 KFP21353.1 - 6.3e-32 110.2 0.5 1.1e-31 109.4 0.5 1.4 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Ni_hydr_CYTB PF01292.20 KFP21353.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Peptidase_A17 PF05380.13 KFP21354.1 - 0.018 15.1 1.2 2.3 8.2 0.1 2.1 1 1 1 2 2 2 0 Pao retrotransposon peptidase SAGA-Tad1 PF12767.7 KFP21356.1 - 2.3e-22 79.9 0.1 7.5e-10 38.9 0.0 2.3 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KFP21356.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AhpC-TSA PF00578.21 KFP21357.1 - 1.8e-13 50.5 0.0 3.3e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KFP21357.1 - 5.6e-13 48.5 0.3 9.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KFP21357.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin Colipase PF01114.18 KFP21357.1 - 0.15 11.8 2.0 0.46 10.2 0.2 2.2 1 1 1 2 2 2 0 Colipase, N-terminal domain PAP2 PF01569.21 KFP21358.1 - 6.4e-19 68.1 4.7 1.1e-18 67.4 4.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFP21358.1 - 1.1e-06 28.4 11.2 4e-06 26.6 11.2 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KFP21358.1 - 0.00088 19.8 3.0 0.00088 19.8 3.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily C-terminal FMO-like PF00743.19 KFP21359.1 - 3.5e-174 580.1 0.6 2.7e-154 514.5 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP21359.1 - 9.2e-16 58.0 0.1 4.2e-10 39.4 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP21359.1 - 2.5e-15 56.5 0.0 2e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP21359.1 - 1.7e-08 34.0 0.3 5.4e-05 22.5 0.0 3.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFP21359.1 - 3.8e-05 23.0 1.0 0.17 11.1 0.0 2.9 3 0 0 3 3 3 2 Thi4 family NAD_binding_9 PF13454.6 KFP21359.1 - 0.00011 22.3 1.8 3.7 7.5 0.1 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFP21359.1 - 0.00012 22.5 0.3 0.013 16.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFP21359.1 - 0.0004 20.1 5.1 0.024 14.2 0.1 3.0 1 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFP21359.1 - 0.00041 20.5 0.6 0.0016 18.6 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFP21359.1 - 0.0035 16.1 1.3 0.59 8.8 0.2 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KFP21359.1 - 0.016 14.3 0.4 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 KFP21359.1 - 0.023 14.3 0.0 0.6 9.7 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KFP21359.1 - 0.08 13.4 0.3 4.9 7.6 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Prenylcys_lyase PF07156.14 KFP21359.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Prenylcysteine lyase GIDA PF01134.22 KFP21359.1 - 0.18 10.8 0.1 6.5 5.7 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFP21359.1 - 0.39 10.0 3.4 0.096 12.0 0.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FMO-like PF00743.19 KFP21360.1 - 3.1e-235 781.6 0.0 3.9e-235 781.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFP21360.1 - 5.7e-16 58.7 0.0 5.3e-12 45.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFP21360.1 - 7.9e-13 48.3 0.0 5.2e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFP21360.1 - 1.8e-08 33.9 0.1 2.3e-07 30.3 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFP21360.1 - 2.7e-06 27.5 0.1 7.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFP21360.1 - 3.5e-05 23.8 0.9 0.79 9.7 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFP21360.1 - 4.6e-05 23.9 0.5 0.0035 17.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFP21360.1 - 0.0023 17.6 3.4 0.91 9.0 0.2 3.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFP21360.1 - 0.0072 15.6 0.1 2.8 7.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KFP21360.1 - 0.013 14.3 0.3 1.1 7.9 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.12 KFP21360.1 - 0.2 11.2 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 KFP21360.1 - 1.6 7.8 3.4 18 4.2 0.5 2.2 2 0 0 2 2 2 0 FAD binding domain AMPK1_CBM PF16561.5 KFP21361.1 - 3.8e-36 123.2 0.2 6.3e-36 122.5 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KFP21361.1 - 8.1e-28 96.5 2.9 1.5e-27 95.6 2.9 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KFP21361.1 - 0.0026 18.1 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Olduvai PF06758.13 KFP21362.1 - 0.19 12.0 6.1 0.59 10.4 6.1 1.8 1 0 0 1 1 1 0 Olduvai domain Prok-JAB PF14464.6 KFP21363.1 - 0.067 13.0 0.1 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain COMM_domain PF07258.14 KFP21363.1 - 0.1 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 COMM domain DUF4164 PF13747.6 KFP21363.1 - 0.24 11.7 8.7 0.45 10.8 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HSCB_C PF07743.13 KFP21363.1 - 0.94 10.0 5.3 4.5 7.8 0.6 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain SMYLE_N PF18615.1 KFP21364.1 - 5.8e-181 602.2 1.9 5.8e-181 602.2 1.9 4.0 2 1 2 4 4 4 2 Short myomegalin-like EB1 binding proteins, N-terminal domain Cnd1 PF12717.7 KFP21364.1 - 0.0028 17.7 1.6 0.0028 17.7 1.6 3.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 2-Hacid_dh_C PF02826.19 KFP21365.1 - 1.4e-59 200.5 0.0 2e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFP21365.1 - 7e-20 71.0 0.0 8.8e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Lectin_C PF00059.21 KFP21366.1 - 8e-09 36.2 0.3 1.4e-08 35.4 0.3 1.4 1 0 0 1 1 1 1 Lectin C-type domain Ank_2 PF12796.7 KFP21368.1 - 4.8e-34 116.8 15.1 1.1e-12 48.4 1.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFP21368.1 - 2.2e-30 103.7 10.9 5.6e-07 29.7 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFP21368.1 - 1.1e-26 92.6 11.6 1.2e-09 38.2 0.4 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP21368.1 - 8.9e-21 71.8 3.8 0.0058 17.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KFP21368.1 - 1.6e-19 70.0 3.0 3.9e-06 27.3 0.3 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Longin PF13774.6 KFP21369.1 - 1.4e-23 82.7 0.1 1.6e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Regulated-SNARE-like domain Pacs-1 PF10254.9 KFP21370.1 - 1e-204 680.2 0.4 2.1e-204 679.1 0.4 1.5 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein LIM PF00412.22 KFP21371.1 - 2.6e-24 85.2 15.3 2.3e-14 53.4 4.0 2.1 2 0 0 2 2 2 2 LIM domain zf-CCHC_5 PF14787.6 KFP21371.1 - 0.013 15.2 0.0 0.013 15.2 0.0 3.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger YacG PF03884.14 KFP21371.1 - 0.016 14.9 8.8 2.5 7.9 0.7 3.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG NinD PF17466.2 KFP21371.1 - 0.035 14.2 16.0 0.18 11.9 0.4 3.4 2 1 1 3 3 3 0 Family of unknown function Ribosomal_L37e PF01907.19 KFP21371.1 - 0.038 14.1 11.8 2 8.6 0.2 3.4 2 1 1 3 3 3 0 Ribosomal protein L37e Metallothio_Pro PF02069.16 KFP21371.1 - 0.041 14.1 7.7 1.7 8.9 1.0 2.6 2 0 0 2 2 2 0 Prokaryotic metallothionein zf-FPG_IleRS PF06827.14 KFP21371.1 - 0.27 11.2 11.6 2 8.3 0.1 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Integrase_H2C2 PF17921.1 KFP21371.1 - 1.4 9.0 6.7 1.3 9.2 0.2 2.5 2 1 0 2 2 2 0 Integrase zinc binding domain zf_UBZ PF18439.1 KFP21371.1 - 1.7 8.3 26.3 0.25 11.0 1.3 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_12 PF11331.8 KFP21371.1 - 1.7 8.5 7.3 2 8.3 2.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KFP21371.1 - 1.7 8.7 11.9 0.2 11.6 4.2 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain c-SKI_SMAD_bind PF08782.10 KFP21371.1 - 2.8 8.2 6.7 17 5.7 1.0 2.3 2 0 0 2 2 2 0 c-SKI Smad4 binding domain LIM PF00412.22 KFP21372.1 - 2.7e-13 49.9 2.3 2.9e-13 49.8 2.3 1.1 1 0 0 1 1 1 1 LIM domain zf_UBZ PF18439.1 KFP21372.1 - 3.9 7.2 7.4 0.35 10.5 1.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF4509 PF14970.6 KFP21373.1 - 1.5e-58 197.8 0.3 1.7e-58 197.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) CECR6_TMEM121 PF14997.6 KFP21374.1 - 4.4e-60 202.9 11.5 8.1e-60 202.0 11.5 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family DUF5083 PF16890.5 KFP21374.1 - 9.5e-05 22.2 1.4 9.5e-05 22.2 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5083) PID PF00640.23 KFP21375.1 - 8.3e-24 84.2 1.9 8.3e-24 84.2 1.9 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Pkinase PF00069.25 KFP21375.1 - 0.027 13.8 1.3 0.043 13.2 1.3 1.2 1 0 0 1 1 1 0 Protein kinase domain Lactamase_B PF00753.27 KFP21375.1 - 0.046 13.7 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily FAM194 PF14977.6 KFP21375.1 - 0.094 12.0 0.5 0.25 10.6 0.4 1.7 1 1 1 2 2 2 0 FAM194 protein SIN1_PH PF16979.5 KFP21375.1 - 0.42 10.9 3.2 0.71 10.2 3.2 1.4 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PID_2 PF14719.6 KFP21375.1 - 1.5 8.7 4.6 0.2 11.5 0.3 1.7 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) DUF4628 PF15429.6 KFP21376.1 - 1.5e-42 146.2 1.6 1.7e-42 146.0 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) Pkinase PF00069.25 KFP21377.1 - 4e-33 114.9 0.0 5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21377.1 - 6.8e-17 61.6 0.1 9.3e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21377.1 - 2.5e-08 33.6 0.0 3.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.22 KFP21377.1 - 3.8e-08 33.0 0.0 7.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kdo PF06293.14 KFP21377.1 - 0.00042 19.7 0.1 0.00067 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP21377.1 - 0.0012 18.9 0.1 0.0019 18.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP21377.1 - 0.0032 17.1 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFP21377.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase UDPGP PF01704.18 KFP21378.1 - 1.6e-65 221.4 0.0 1.9e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase F5_F8_type_C PF00754.25 KFP21379.1 - 4.4e-14 52.7 0.0 4.9e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Pkinase_Tyr PF07714.17 KFP21380.1 - 1.5e-85 286.7 0.0 1.9e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP21380.1 - 2.7e-43 148.2 0.0 2.2e-41 142.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.25 KFP21380.1 - 0.00032 20.8 0.0 0.0048 17.0 0.0 2.4 2 0 0 2 2 2 1 F5/8 type C domain Haspin_kinase PF12330.8 KFP21380.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Shisa PF13908.6 KFP21380.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KFP21380.1 - 0.17 12.9 0.0 0.31 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) adh_short PF00106.25 KFP21381.1 - 7e-14 51.7 0.0 1.1e-11 44.6 0.0 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP21381.1 - 5.3e-09 36.0 0.0 2.9e-05 23.8 0.0 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase OLF PF02191.16 KFP21382.1 - 1.2e-85 287.0 11.1 1.7e-85 286.6 11.1 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFP21382.1 - 0.0012 18.8 0.3 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Neurogenesis glycoprotein bZIP_1 PF00170.21 KFP21383.1 - 3.8e-10 39.7 13.6 8.8e-10 38.5 13.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP21383.1 - 3.4e-05 23.8 12.9 3.4e-05 23.8 12.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP21383.1 - 0.0014 19.1 7.5 0.0014 19.1 7.5 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor YabA PF06156.13 KFP21383.1 - 3.4 8.4 5.3 0.42 11.3 0.7 1.9 2 0 0 2 2 2 0 Initiation control protein YabA NAD_binding_10 PF13460.6 KFP21384.1 - 0.00032 20.6 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RGS PF00615.19 KFP21385.1 - 6.6e-29 100.6 3.0 1.3e-28 99.6 3.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain Gag_p19 PF02228.16 KFP21385.1 - 0.033 14.6 0.0 0.076 13.5 0.0 1.6 1 1 0 1 1 1 0 Major core protein p19 RGS PF00615.19 KFP21386.1 - 8.7e-37 126.0 1.8 1.2e-36 125.6 1.8 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Sas6_CC PF18594.1 KFP21386.1 - 0.058 13.2 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Polo_box_3 PF18544.1 KFP21386.1 - 0.076 13.7 0.3 0.65 10.7 0.0 2.0 2 0 0 2 2 2 0 Polo box domain APCDDC PF14921.6 KFP21387.1 - 3.9e-119 396.3 0.0 1.5e-87 293.0 0.0 2.1 2 0 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 Motile_Sperm PF00635.26 KFP21388.1 - 1.7e-29 101.8 0.1 3.4e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ZapB PF06005.12 KFP21388.1 - 0.0068 16.8 0.7 0.011 16.1 0.7 1.3 1 0 0 1 1 1 1 Cell division protein ZapB Com_YlbF PF06133.11 KFP21388.1 - 0.034 14.7 0.7 0.059 14.0 0.7 1.3 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA LcrG PF07216.12 KFP21388.1 - 0.042 13.8 0.2 0.072 13.0 0.2 1.4 1 0 0 1 1 1 0 LcrG protein IF2_N PF04760.15 KFP21388.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region CHD5 PF04420.14 KFP21388.1 - 0.14 12.0 1.1 0.45 10.4 0.9 1.8 2 0 0 2 2 2 0 CHD5-like protein Ras PF00071.22 KFP21389.1 - 8.3e-53 178.3 0.0 9.5e-53 178.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21389.1 - 1.7e-32 112.2 0.0 2.6e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP21389.1 - 4e-12 45.9 0.0 4.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP21389.1 - 0.00025 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DIT1_PvcA PF05141.12 KFP21389.1 - 0.065 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CNTF PF01110.17 KFP21389.1 - 0.068 12.5 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor RsgA_GTPase PF03193.16 KFP21389.1 - 0.11 12.5 0.4 4.6 7.1 0.1 2.4 1 1 1 2 2 2 0 RsgA GTPase HEAT PF02985.22 KFP21390.1 - 6.1e-25 85.1 10.6 0.0087 16.2 0.0 8.5 7 0 0 7 7 7 7 HEAT repeat HEAT_2 PF13646.6 KFP21390.1 - 1.1e-08 35.3 1.3 0.19 12.1 0.0 6.6 4 2 2 7 7 7 3 HEAT repeats WRNPLPNID PF15017.6 KFP21390.1 - 3e-07 31.2 0.1 3e-07 31.2 0.1 3.0 3 0 0 3 3 3 1 Putative WW-binding domain and destruction box Vac14_Fab1_bd PF12755.7 KFP21390.1 - 0.0029 18.2 1.0 5.2 7.7 0.0 4.6 4 2 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP21390.1 - 0.0033 17.5 7.9 7.7 6.5 0.1 5.6 4 2 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Ins134_P3_kin PF05770.11 KFP21390.1 - 0.041 13.4 3.0 0.54 9.7 0.1 2.7 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain HEAT_EZ PF13513.6 KFP21390.1 - 0.047 14.2 0.2 2.6 8.6 0.2 3.5 3 0 0 3 3 3 0 HEAT-like repeat OSCP PF00213.18 KFP21390.1 - 0.27 11.3 2.1 1.1 9.4 0.1 2.7 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit MID_MedPIWI PF18296.1 KFP21390.1 - 10 5.9 10.5 0.2 11.4 1.0 2.2 2 0 0 2 2 2 0 MID domain of medPIWI LLC1 PF14945.6 KFP21391.1 - 2.1e-45 154.1 1.0 2.3e-45 154.0 1.0 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein SAYSvFN PF10260.9 KFP21392.1 - 0.2 11.6 0.2 0.35 10.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) PEPCK_GTP PF00821.18 KFP21393.1 - 1.5e-168 560.2 0.4 1.9e-168 559.9 0.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KFP21393.1 - 1e-97 326.0 0.0 1.4e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain TPK_catalytic PF04263.16 KFP21393.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain zf-H2C2_2 PF13465.6 KFP21394.1 - 1.4e-41 139.1 56.0 1.8e-08 34.4 0.4 8.0 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 KFP21394.1 - 1.8e-23 81.6 66.7 3.6e-05 24.0 1.0 9.1 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21394.1 - 5.2e-21 73.5 63.7 0.0031 18.2 0.4 9.1 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFP21394.1 - 1.3e-16 60.1 65.5 7.8e-06 25.5 1.5 9.8 9 1 0 9 9 9 6 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KFP21394.1 - 3.3e-05 23.8 1.1 3.3e-05 23.8 1.1 9.2 11 0 0 11 11 11 2 C2H2-type zinc finger AKAP95 PF04988.12 KFP21394.1 - 0.0065 16.7 0.6 0.0065 16.7 0.6 3.8 3 2 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) GAGA PF09237.11 KFP21394.1 - 0.0072 16.1 12.1 0.98 9.3 0.0 5.7 3 1 4 7 7 7 1 GAGA factor RNA_POL_M_15KD PF02150.16 KFP21394.1 - 0.026 14.4 22.8 2.1 8.3 0.5 6.5 7 0 0 7 7 7 0 RNA polymerases M/15 Kd subunit zf-C2H2_jaz PF12171.8 KFP21394.1 - 0.034 14.4 45.0 1.3 9.4 0.2 8.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP21394.1 - 0.055 13.9 0.4 0.055 13.9 0.4 7.4 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFP21394.1 - 0.055 13.9 2.6 0.055 13.9 2.6 7.7 2 2 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 KFP21394.1 - 0.065 14.0 27.6 0.59 10.9 0.7 4.2 3 1 0 4 4 4 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFP21394.1 - 0.066 13.0 0.2 0.066 13.0 0.2 7.8 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KFP21394.1 - 0.22 11.9 37.0 8.2 6.8 7.1 5.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Pox_A3L PF05288.11 KFP21394.1 - 2.8 8.0 6.1 8.6 6.4 0.2 3.8 3 1 1 4 4 4 0 Poxvirus A3L Protein WD40 PF00400.32 KFP21395.1 - 1.1e-10 41.9 17.4 0.02 15.8 0.2 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21395.1 - 0.00071 19.8 0.0 0.97 9.8 0.2 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP21395.1 - 0.0097 14.6 0.4 0.92 8.1 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TP6A_N PF04406.14 KFP21396.1 - 5.4e-24 84.0 0.3 9.4e-24 83.2 0.3 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF760 PF05542.11 KFP21396.1 - 0.007 16.7 0.1 0.41 11.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF760) TGFb_propeptide PF00688.18 KFP21397.1 - 1.3e-54 185.6 0.0 1.9e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP21397.1 - 4e-37 127.3 1.9 4.2e-37 127.3 0.7 1.7 2 0 0 2 2 2 1 Transforming growth factor beta like domain TF_AP-2 PF03299.14 KFP21398.1 - 3.9e-88 294.6 0.0 4.6e-88 294.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor AP-2 4PPT_N PF17837.1 KFP21398.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Rtf2 PF04641.12 KFP21399.1 - 2.3e-85 286.1 11.6 2.8e-85 285.9 11.6 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KFP21399.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KFP21399.1 - 0.022 14.6 0.5 0.15 11.9 0.0 2.7 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MAS20 PF02064.15 KFP21399.1 - 1.1 9.4 4.6 0.69 10.0 2.6 1.6 1 1 1 2 2 2 0 MAS20 protein import receptor Branch PF02485.21 KFP21400.1 - 1.3e-52 178.8 0.3 1.9e-52 178.2 0.3 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.32 KFP21402.1 - 3.6e-33 113.1 1.8 2.1e-06 28.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 KFP21402.1 - 8.7e-23 79.8 0.3 1.5e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 KFP21402.1 - 2.9e-12 46.7 0.0 0.017 15.4 0.0 4.7 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KFP21402.1 - 6.5e-06 24.7 0.1 0.00012 20.6 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KFP21402.1 - 0.0017 17.4 1.0 0.6 9.0 0.2 2.9 1 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1279 PF06916.13 KFP21403.1 - 2e-28 98.7 1.1 2.4e-28 98.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) 7tm_1 PF00001.21 KFP21404.1 - 1.3e-36 126.3 38.2 4e-35 121.4 38.2 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP21404.1 - 3.4e-08 33.6 29.1 1.3e-07 31.6 24.8 2.7 1 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP21404.1 - 5e-06 26.1 38.1 1.2e-05 24.9 38.1 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP21404.1 - 0.00045 19.9 28.1 0.00045 19.9 28.1 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ANAPC9 PF12856.7 KFP21405.1 - 0.038 14.2 1.9 0.15 12.2 1.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 9 C1q PF00386.21 KFP21406.1 - 3.7e-19 69.2 0.4 4.1e-19 69.1 0.4 1.0 1 0 0 1 1 1 1 C1q domain PH_2 PF08458.10 KFP21406.1 - 0.037 14.4 0.0 7.9 6.9 0.0 2.1 1 1 1 2 2 2 0 Plant pleckstrin homology-like region Prefoldin_2 PF01920.20 KFP21408.1 - 2.5e-25 88.5 9.1 3.1e-25 88.2 9.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 KFP21408.1 - 0.00019 21.8 6.1 0.0097 16.4 1.1 2.2 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 KFP21408.1 - 0.00067 19.9 12.0 0.0031 17.8 12.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) KxDL PF10241.9 KFP21408.1 - 0.002 18.4 5.9 0.017 15.4 0.8 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein Prefoldin PF02996.17 KFP21408.1 - 0.0022 17.9 8.8 0.043 13.7 8.8 2.1 1 1 0 1 1 1 1 Prefoldin subunit DUF5320 PF17253.2 KFP21408.1 - 0.0026 18.8 4.7 0.0074 17.3 0.4 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5320) Helo_like_N PF17111.5 KFP21408.1 - 0.0061 16.0 5.6 0.4 10.0 0.8 2.1 1 1 1 2 2 2 2 Fungal N-terminal domain of STAND proteins FlxA PF14282.6 KFP21408.1 - 0.0088 16.0 7.7 0.46 10.5 0.3 2.3 2 0 0 2 2 2 2 FlxA-like protein Med30 PF11315.8 KFP21408.1 - 0.012 15.8 4.4 0.015 15.5 4.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 UPF0054 PF02130.17 KFP21408.1 - 0.012 15.4 2.9 0.031 14.1 2.9 1.7 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 DUF4618 PF15397.6 KFP21408.1 - 0.013 15.0 6.4 0.11 11.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4140 PF13600.6 KFP21408.1 - 0.013 15.9 5.4 0.69 10.4 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 KFP21408.1 - 0.014 15.6 7.0 0.91 9.7 1.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 KFP21408.1 - 0.015 14.8 3.6 0.033 13.6 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus RraB PF06877.11 KFP21408.1 - 0.015 16.0 2.6 0.17 12.6 0.2 2.3 1 1 1 2 2 2 0 Regulator of ribonuclease activity B DivIC PF04977.15 KFP21408.1 - 0.018 14.8 5.6 0.62 9.9 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4854 PF16146.5 KFP21408.1 - 0.02 15.2 3.1 0.023 15.0 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4854) Cep57_CLD_2 PF14197.6 KFP21408.1 - 0.022 14.8 8.6 0.91 9.7 1.0 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 KFP21408.1 - 0.023 14.8 12.3 0.19 11.8 4.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.13 KFP21408.1 - 0.027 14.6 7.5 0.021 14.9 5.8 1.7 1 1 0 1 1 1 0 DivIVA protein BLI1 PF17324.2 KFP21408.1 - 0.031 14.9 6.3 0.33 11.6 1.1 2.2 2 0 0 2 2 2 0 BLOC-1 interactor 1 ABC_tran_CTD PF16326.5 KFP21408.1 - 0.033 14.4 10.6 0.35 11.2 3.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Rx_N PF18052.1 KFP21408.1 - 0.035 14.4 5.4 0.11 12.8 0.9 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Seryl_tRNA_N PF02403.22 KFP21408.1 - 0.036 14.3 7.9 1.2 9.5 0.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.11 KFP21408.1 - 0.037 14.3 7.4 0.43 10.8 1.6 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 KFP21408.1 - 0.044 13.8 5.9 0.094 12.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFP21408.1 - 0.046 14.1 9.0 1.5 9.2 1.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2721 PF11026.8 KFP21408.1 - 0.064 13.1 0.8 5.1 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) YabA PF06156.13 KFP21408.1 - 0.075 13.7 6.8 0.13 12.9 0.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CdvA PF18822.1 KFP21408.1 - 0.084 12.7 9.4 0.092 12.6 2.5 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Mod_r PF07200.13 KFP21408.1 - 0.089 12.9 9.3 0.43 10.7 9.3 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.13 KFP21408.1 - 0.093 12.3 4.6 0.66 9.5 0.4 2.1 2 0 0 2 2 2 0 fzo-like conserved region Atg14 PF10186.9 KFP21408.1 - 0.094 11.8 2.9 0.19 10.8 2.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KFP21408.1 - 0.12 12.5 11.7 0.18 11.9 11.7 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GvpL_GvpF PF06386.11 KFP21408.1 - 0.14 12.1 2.6 0.46 10.4 0.2 1.9 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF APG6_N PF17675.1 KFP21408.1 - 0.17 12.4 12.9 0.77 10.3 4.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region CCDC-167 PF15188.6 KFP21408.1 - 0.25 11.7 8.5 0.75 10.2 3.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.19 KFP21408.1 - 0.26 9.2 4.1 0.3 8.9 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2205 PF10224.9 KFP21408.1 - 0.27 11.2 6.0 0.17 11.9 1.8 2.2 2 0 0 2 2 2 0 Short coiled-coil protein DASH_Spc34 PF08657.10 KFP21408.1 - 0.3 10.9 7.7 1.2 8.9 6.8 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 Mt_ATP-synt_D PF05873.12 KFP21408.1 - 0.3 10.9 5.2 0.69 9.8 0.2 2.1 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4988 PF16378.5 KFP21408.1 - 0.34 10.6 3.8 2.4 7.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function FAM76 PF16046.5 KFP21408.1 - 0.34 10.2 7.2 0.54 9.6 7.2 1.3 1 1 0 1 1 1 0 FAM76 protein Med9 PF07544.13 KFP21408.1 - 0.35 11.0 13.9 1.2 9.2 3.7 3.3 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 KFP21408.1 - 0.4 10.7 13.0 2 8.4 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KFP21408.1 - 0.43 11.0 9.6 3.4 8.1 1.5 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain HalX PF08663.10 KFP21408.1 - 0.49 10.7 5.6 8 6.9 1.6 2.4 2 0 0 2 2 2 0 HalX domain FmiP_Thoc5 PF09766.9 KFP21408.1 - 0.5 9.6 7.7 1.8 7.7 1.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DASH_Dam1 PF08653.10 KFP21408.1 - 0.53 10.1 2.3 6.6 6.6 0.2 2.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 eIF3_N PF09440.10 KFP21408.1 - 0.62 10.5 6.5 1 9.8 0.4 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain UPF0449 PF15136.6 KFP21408.1 - 0.62 10.6 8.4 2.7 8.5 1.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2203 PF09969.9 KFP21408.1 - 0.64 10.8 5.7 2.2 9.0 5.2 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Med4 PF10018.9 KFP21408.1 - 0.77 9.4 8.4 1.3 8.7 0.9 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4407 PF14362.6 KFP21408.1 - 0.83 8.9 6.9 2 7.7 6.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Plk4_PB2 PF18409.1 KFP21408.1 - 0.93 10.2 6.0 13 6.5 6.1 2.1 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 TBCA PF02970.16 KFP21408.1 - 0.93 9.9 10.4 3.5 8.0 9.8 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor A AAA_23 PF13476.6 KFP21408.1 - 1.1 9.7 11.2 1.6 9.2 11.2 1.3 1 1 0 1 1 1 0 AAA domain KfrA_N PF11740.8 KFP21408.1 - 1.1 9.9 8.1 0.95 10.2 6.1 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term BORCS7 PF16088.5 KFP21408.1 - 1.2 9.4 7.0 5.7 7.3 0.3 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 FAM167 PF11652.8 KFP21408.1 - 1.3 9.6 5.2 0.7 10.4 0.7 2.3 1 1 1 2 2 2 0 FAM167 GrpE PF01025.19 KFP21408.1 - 1.4 8.5 10.3 2.1 8.0 2.2 2.1 2 0 0 2 2 2 0 GrpE Fmp27_WPPW PF10359.9 KFP21408.1 - 1.6 7.5 9.2 0.51 9.1 1.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CHD5 PF04420.14 KFP21408.1 - 1.7 8.5 4.1 2.5 7.9 0.7 2.0 2 0 0 2 2 2 0 CHD5-like protein SlyX PF04102.12 KFP21408.1 - 1.8 9.2 8.4 2.6 8.7 1.2 2.5 2 1 0 2 2 2 0 SlyX ERM PF00769.19 KFP21408.1 - 2.2 8.1 13.3 0.52 10.1 4.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.21 KFP21408.1 - 2.2 8.4 10.3 4.1 7.6 3.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor YtxH PF12732.7 KFP21408.1 - 3.3 8.3 5.2 6.4 7.4 0.1 2.3 2 0 0 2 2 2 0 YtxH-like protein Carbpep_Y_N PF05388.11 KFP21408.1 - 4.2 7.9 7.1 4.8 7.7 0.4 2.8 2 1 1 3 3 3 0 Carboxypeptidase Y pro-peptide Med7 PF05983.11 KFP21408.1 - 7.9 6.5 8.9 8.8 6.4 2.5 2.2 2 0 0 2 2 2 0 MED7 protein DUF812 PF05667.11 KFP21408.1 - 8.4 5.1 15.9 4.8 6.0 4.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) p450 PF00067.22 KFP21409.1 - 1.4e-82 277.9 0.1 1.6e-82 277.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KFP21410.1 - 4.8e-20 70.8 50.3 0.00017 21.9 1.0 9.0 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21410.1 - 3.8e-18 64.6 53.6 0.001 19.7 0.9 9.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP21410.1 - 1.3e-09 38.0 63.7 1.1e-07 32.0 0.4 11.8 13 0 0 13 13 12 4 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KFP21410.1 - 4.4e-06 27.4 15.4 0.00011 22.8 1.4 5.7 4 1 1 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KFP21410.1 - 4.6e-05 23.1 3.1 4.6e-05 23.1 3.1 8.7 9 1 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KFP21410.1 - 0.00027 21.2 33.8 0.00069 19.9 2.2 7.2 5 2 1 7 7 6 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KFP21410.1 - 0.014 15.4 1.0 0.014 15.4 1.0 8.0 7 2 0 7 7 7 0 C2H2-type zinc finger CpXC PF14353.6 KFP21410.1 - 0.097 12.7 14.2 4 7.5 0.1 5.7 4 1 0 4 4 4 0 CpXC protein zf-C2HC_2 PF13913.6 KFP21410.1 - 0.17 11.8 15.0 0.65 10.0 0.8 5.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 KFP21410.1 - 0.43 9.7 14.3 3.4 6.7 0.7 3.8 2 1 1 3 3 3 0 Putative actin-like family zf-C2H2_jaz PF12171.8 KFP21410.1 - 0.67 10.3 28.1 0.8 10.1 0.9 6.4 6 0 0 6 6 5 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KFP21410.1 - 0.85 9.3 15.6 4.8 6.9 0.1 5.4 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_1 PF00130.22 KFP21410.1 - 1.7 8.6 18.8 1.4 8.8 0.8 4.9 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 KFP21410.1 - 2 8.3 5.6 1.7 8.5 0.1 3.0 3 0 0 3 3 2 0 GAGA factor DUF2256 PF10013.9 KFP21410.1 - 2.3 8.4 10.2 43 4.3 0.0 5.3 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) AKAP95 PF04988.12 KFP21410.1 - 4.6 7.4 17.7 2.8 8.1 1.8 4.1 4 0 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KFP21412.1 - 8.9e-10 38.6 28.7 0.049 14.5 0.1 6.1 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP21412.1 - 1.9e-09 37.8 26.9 0.005 17.1 0.3 4.7 3 1 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP21412.1 - 1.3e-05 25.8 16.7 0.18 12.5 0.8 5.1 3 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 KFP21412.1 - 0.00031 21.0 34.3 0.37 11.3 0.8 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.7 KFP21412.1 - 0.0022 18.3 12.1 0.11 13.0 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP21412.1 - 0.019 15.2 15.5 0.035 14.4 0.2 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFP21412.1 - 0.056 13.5 24.7 0.45 10.6 0.2 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_Tnp_IS1 PF03811.13 KFP21412.1 - 0.52 10.1 3.5 8.9 6.1 0.9 2.9 2 0 0 2 2 2 0 InsA N-terminal domain PhnA_Zn_Ribbon PF08274.12 KFP21412.1 - 1.2 9.2 3.7 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-CpG_bind_C PF12269.8 KFP21412.1 - 2.3 7.9 13.8 0.11 12.3 2.1 3.1 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-H2C2_2 PF13465.6 KFP21412.1 - 3.3 8.3 18.8 7.1 7.2 0.3 5.8 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_12 PF18658.1 KFP21412.1 - 5.3 6.7 11.0 5.4 6.7 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger C2H2-type RHD_dimer PF16179.5 KFP21414.1 - 4.3e-25 87.7 0.4 1.1e-24 86.4 0.4 1.7 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 KFP21414.1 - 1.9e-22 80.0 0.5 5.8e-22 78.4 0.5 1.8 1 1 0 1 1 1 1 Rel homology DNA-binding domain TIG PF01833.24 KFP21414.1 - 2.8e-06 27.3 0.2 1.6e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ion_trans PF00520.31 KFP21415.1 - 2.6e-37 128.4 9.3 3.8e-37 127.8 9.3 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP21415.1 - 1.3e-26 92.8 0.0 2.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP21415.1 - 4.4e-14 52.2 3.0 4.4e-14 52.2 3.0 2.0 2 0 0 2 2 2 1 Ion channel ThiF PF00899.21 KFP21416.1 - 6.6e-29 101.0 0.0 9.2e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KFP21416.1 - 6.8e-11 42.6 0.0 1.2e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Glycos_transf_2 PF00535.26 KFP21417.1 - 5.5e-33 114.2 0.0 6.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFP21417.1 - 1.8e-09 37.9 0.0 4.1e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFP21417.1 - 4.6e-05 23.0 0.0 8.4e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KFP21417.1 - 0.00042 19.9 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KFP21417.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Homeodomain PF00046.29 KFP21418.1 - 1.2e-07 31.5 0.2 5.2e-07 29.4 0.5 2.0 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 KFP21418.1 - 0.0007 20.2 53.3 0.011 16.5 0.3 9.4 9 0 0 9 9 9 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFP21418.1 - 0.049 14.3 11.5 4.1 8.1 0.5 4.9 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats Homeobox_KN PF05920.11 KFP21418.1 - 0.077 12.9 0.3 0.28 11.1 0.3 2.0 1 0 0 1 1 1 0 Homeobox KN domain zf-Di19 PF05605.12 KFP21418.1 - 0.089 13.1 0.2 0.089 13.1 0.2 7.4 7 2 1 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding Thioredoxin_3 PF13192.6 KFP21418.1 - 0.36 10.9 4.4 8.5 6.5 0.0 4.7 5 0 0 5 5 5 0 Thioredoxin domain zf_C2H2_ZHX PF18387.1 KFP21418.1 - 0.41 10.3 0.0 0.41 10.3 0.0 5.4 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain GP38 PF05268.11 KFP21418.1 - 0.48 10.0 2.6 0.82 9.3 2.6 1.3 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 zf-C2H2_9 PF16293.5 KFP21418.1 - 2.9 7.8 12.1 0.13 12.1 0.2 4.3 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) PB1 PF00564.24 KFP21419.1 - 7e-13 48.3 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 KFP21419.1 - 3.3e-11 43.4 0.0 6.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP21419.1 - 2.7e-08 33.5 0.1 5.3e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.27 KFP21420.1 - 3.3e-80 269.1 0.0 4.4e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP21420.1 - 0.0001 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP21420.1 - 0.0046 16.9 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP21420.1 - 0.072 13.2 0.1 0.29 11.2 0.1 2.1 1 1 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KFP21420.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RVT_1 PF00078.27 KFP21422.1 - 3.4e-24 85.6 0.1 7.9e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP21422.1 - 1.2e-06 28.4 0.1 3e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Hepar_II_III_N PF16889.5 KFP21422.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Heparinase II/III N-terminus TMEM189_B_dmain PF10520.9 KFP21423.1 - 8e-29 101.0 2.1 1.2e-28 100.4 2.1 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain UQ_con PF00179.26 KFP21423.1 - 6.5e-18 64.7 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP21423.1 - 0.038 14.3 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain zf-C2H2 PF00096.26 KFP21424.1 - 5.4e-25 86.4 31.6 4.9e-06 26.7 0.7 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21424.1 - 3.9e-19 67.7 32.1 9.9e-05 22.9 1.4 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP21424.1 - 1.3e-14 54.0 18.7 0.00037 20.7 0.2 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFP21424.1 - 5.6e-14 51.8 38.5 2.5e-07 30.8 0.5 6.0 5 2 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 KFP21424.1 - 1.8e-09 37.6 17.7 0.0026 18.1 0.8 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFP21424.1 - 2.1e-08 34.0 33.7 0.0013 18.7 1.2 5.5 5 1 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 KFP21424.1 - 1.7e-06 28.4 25.3 0.018 15.5 0.7 4.9 1 1 4 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KFP21424.1 - 0.0018 18.6 22.7 0.81 10.1 1.0 4.9 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KFP21424.1 - 0.0052 16.9 21.0 0.19 11.9 0.7 4.3 1 1 4 5 5 5 3 Zinc ribbon domain zf-C2HC_2 PF13913.6 KFP21424.1 - 0.0084 16.0 13.6 0.54 10.2 0.6 4.6 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-BED PF02892.15 KFP21424.1 - 0.0092 16.0 28.1 0.093 12.8 0.8 5.1 2 2 3 5 5 5 3 BED zinc finger zf-AN1 PF01428.16 KFP21424.1 - 0.0093 16.1 21.0 2.9 8.1 1.7 5.2 5 0 0 5 5 5 1 AN1-like Zinc finger PyrI_C PF02748.15 KFP21424.1 - 0.034 14.1 15.1 0.72 9.8 2.1 4.8 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 KFP21424.1 - 0.36 10.6 27.8 4.4 7.2 0.6 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-CHY PF05495.12 KFP21424.1 - 1.1 9.9 27.4 1.2 9.7 6.4 2.7 1 1 1 2 2 2 0 CHY zinc finger zf_ZIC PF18366.1 KFP21424.1 - 1.1 9.4 14.1 3.9 7.7 1.6 4.8 1 1 4 5 5 5 0 Zic proteins zinc finger domain zinc_ribbon_15 PF17032.5 KFP21424.1 - 1.7 9.5 19.8 0.9 10.3 8.3 3.0 1 1 1 2 2 1 0 zinc-ribbon family Spt46 PF17734.1 KFP21424.1 - 1.7 8.4 17.1 0.96 9.2 4.2 3.6 1 1 2 4 4 4 0 Spermatogenesis-associated protein 46 XPA_N PF01286.18 KFP21424.1 - 2.4 8.3 15.4 3 8.0 0.1 4.7 5 0 0 5 5 5 0 XPA protein N-terminal DUF2180 PF09947.9 KFP21424.1 - 2.7 8.0 9.4 0.69 9.9 2.8 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Zn_Tnp_IS1595 PF12760.7 KFP21424.1 - 2.9 7.9 28.7 2.1 8.4 0.6 3.8 3 1 0 3 3 3 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 KFP21424.1 - 4.1 7.6 18.7 5.2 7.3 0.0 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Sprouty PF05210.13 KFP21424.1 - 4.6 7.7 18.5 0.33 11.4 2.0 2.7 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-Di19 PF05605.12 KFP21425.1 - 2.3e-18 66.2 2.4 2.3e-18 66.2 2.4 3.2 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf_C2HC_14 PF18574.1 KFP21425.1 - 1.6e-15 56.6 5.9 1.6e-15 56.6 5.9 2.2 2 0 0 2 2 2 1 C2HC Zing finger domain DND1_DSRM PF14709.7 KFP21425.1 - 0.024 14.9 0.0 0.074 13.3 0.0 1.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 zf-C2H2_4 PF13894.6 KFP21425.1 - 0.025 15.4 1.1 0.025 15.4 1.1 4.9 5 1 0 5 5 5 0 C2H2-type zinc finger zf-RRN7 PF11781.8 KFP21425.1 - 0.034 13.8 7.5 0.85 9.4 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 tRNA-synt_1g PF09334.11 KFP21425.1 - 0.27 10.0 3.6 0.13 11.0 1.5 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (M) DZR PF12773.7 KFP21425.1 - 0.29 11.2 17.2 2.6 8.1 1.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 KFP21425.1 - 6.2 6.5 9.1 2.8 7.6 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C4pol PF14260.6 KFP21425.1 - 8.4 6.9 17.3 2.2 8.8 9.7 2.5 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-B_box PF00643.24 KFP21426.1 - 2.3 8.4 17.8 1.3 9.2 4.4 3.1 2 1 0 2 2 2 0 B-box zinc finger Glyco_transf_7N PF13733.6 KFP21428.1 - 1e-55 187.0 0.0 1.6e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KFP21428.1 - 4.9e-29 99.8 0.4 8.5e-29 99.0 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Staufen_C PF16482.5 KFP21429.1 - 1.6e-55 186.0 2.0 9.7e-50 167.4 0.0 5.0 5 0 0 5 5 5 3 Staufen C-terminal domain dsrm PF00035.26 KFP21429.1 - 2.3e-48 162.8 3.8 2.2e-12 47.5 0.0 4.9 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFP21429.1 - 8.8e-07 29.1 7.0 0.24 11.7 0.0 5.4 5 2 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.16 KFP21429.1 - 0.042 14.2 0.1 6.2 7.3 0.0 3.3 3 0 0 3 3 3 0 LPP20 lipoprotein CAS_CSE1 PF03378.15 KFP21430.1 - 1.5e-176 587.3 5.7 2e-176 586.9 3.4 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KFP21430.1 - 1.9e-168 560.1 5.3 4e-168 559.0 5.3 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KFP21430.1 - 2.6e-11 43.3 0.3 1.6e-10 40.7 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFP21430.1 - 0.012 15.6 0.0 0.012 15.6 0.0 4.0 4 1 0 5 5 5 0 Exportin 1-like protein PUF PF00806.19 KFP21430.1 - 0.049 13.3 0.0 1.2 8.9 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF3385 PF11865.8 KFP21430.1 - 0.21 11.5 2.8 0.41 10.5 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Sec7 PF01369.20 KFP21431.1 - 4.4e-72 241.6 0.6 1.2e-71 240.2 0.6 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFP21431.1 - 4.4e-51 172.9 3.4 1.1e-50 171.6 2.2 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KFP21431.1 - 1.9e-37 128.7 0.1 2.1e-36 125.2 0.1 2.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KFP21431.1 - 1.8e-34 117.4 0.1 1.8e-34 117.4 0.1 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Cmyb_C PF09316.10 KFP21432.1 - 2.1e-65 219.4 4.7 5.3e-65 218.1 4.7 1.7 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.31 KFP21432.1 - 3.2e-50 168.1 17.3 3.3e-17 62.4 3.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP21432.1 - 2.8e-45 152.4 13.6 4.9e-19 68.3 2.7 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP21432.1 - 1.3e-07 31.4 5.9 0.006 16.5 0.0 3.5 2 1 1 3 3 3 3 Myb DNA-binding like SLIDE PF09111.10 KFP21432.1 - 3.6e-06 27.0 1.3 0.5 10.4 0.0 3.5 1 1 2 3 3 3 3 SLIDE Sigma70_r4_2 PF08281.12 KFP21432.1 - 0.0013 18.3 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 SANT_DAMP1_like PF16282.5 KFP21432.1 - 0.0085 16.3 5.5 1.8 8.8 0.1 3.5 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KFP21432.1 - 0.03 14.4 5.8 3.3 7.9 1.4 3.5 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SbcD_C PF12320.8 KFP21432.1 - 0.049 13.9 0.5 0.099 13.0 0.1 1.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Atg29_N PF18388.1 KFP21432.1 - 0.12 12.2 0.6 0.71 9.7 0.0 2.4 2 0 0 2 2 2 0 Atg29 N-terminal domain Myb_DNA-bind_2 PF08914.11 KFP21432.1 - 7.8 6.8 6.8 19 5.5 0.2 3.4 1 1 2 3 3 3 0 Rap1 Myb domain ABC_transp_aux PF09822.9 KFP21434.1 - 5.4e-08 32.6 0.0 9.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KFP21434.1 - 0.00097 18.1 0.0 0.086 11.7 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.25 KFP21435.1 - 1.3e-68 231.2 0.0 1.6e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21435.1 - 8.9e-35 120.2 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFP21435.1 - 3.5e-06 27.6 0.2 6.9e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP21435.1 - 2.5e-05 23.8 0.1 8.5e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP21435.1 - 0.0033 16.8 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFP21435.1 - 0.008 15.8 0.0 0.63 9.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Aa_trans PF01490.18 KFP21436.1 - 2.4e-93 313.1 19.7 2.8e-93 312.9 19.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein p53-inducible11 PF14936.6 KFP21436.1 - 3.4 7.7 6.3 25 4.9 0.2 2.5 1 1 1 2 2 2 0 Tumour protein p53-inducible protein 11 CitMHS PF03600.16 KFP21436.1 - 8.4 5.5 9.1 17 4.5 9.1 1.5 1 1 0 1 1 1 0 Citrate transporter Actin PF00022.19 KFP21437.1 - 1.8e-41 142.1 0.0 5.1e-39 134.0 0.0 2.2 1 1 0 1 1 1 1 Actin DUF1542 PF07564.11 KFP21437.1 - 0.012 15.7 2.8 0.076 13.1 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF2777 PF10949.8 KFP21437.1 - 0.074 12.7 1.5 0.15 11.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DUF4265 PF14085.6 KFP21437.1 - 0.1 12.5 0.1 16 5.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4265) GH-E PF14410.6 KFP21437.1 - 0.11 12.9 0.4 0.34 11.3 0.4 1.8 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Ank_2 PF12796.7 KFP21439.1 - 8.7e-32 109.6 5.4 3.5e-17 62.8 2.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP21439.1 - 8.2e-31 106.0 7.8 5.4e-14 52.4 0.5 5.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFP21439.1 - 5.7e-27 92.9 14.2 2.7e-08 33.9 0.6 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP21439.1 - 1.6e-24 85.6 10.6 7.6e-12 45.2 1.9 4.6 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP21439.1 - 3.7e-20 69.9 8.9 0.00011 22.4 0.2 5.5 5 0 0 5 5 5 4 Ankyrin repeat DUF4337 PF14235.6 KFP21439.1 - 0.094 12.8 3.9 0.21 11.7 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4770 PF15994.5 KFP21439.1 - 0.12 12.6 1.7 0.24 11.6 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM83 PF07894.12 KFP21440.1 - 4.8e-54 183.8 0.0 6.8e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 FAM83 A-H PLDc_2 PF13091.6 KFP21440.1 - 0.00015 21.7 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 PLD-like domain Dehydrin PF00257.19 KFP21440.1 - 1.1 9.8 6.5 1.8 9.1 6.5 1.3 1 0 0 1 1 1 0 Dehydrin FAM83 PF07894.12 KFP21441.1 - 2.9e-36 125.4 0.3 1.4e-23 83.8 0.4 2.1 1 1 1 2 2 2 2 FAM83 A-H DUF4462 PF14692.6 KFP21443.1 - 0.063 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Topoisom_I PF01028.20 KFP21445.1 - 3.3e-103 343.9 3.6 3.3e-103 343.9 3.6 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFP21445.1 - 2.5e-101 337.6 8.1 2.5e-101 337.6 8.1 5.3 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFP21445.1 - 1.3e-33 114.8 0.5 1.3e-33 114.8 0.5 3.0 2 0 0 2 2 2 1 C-terminal topoisomerase domain PI-PLC-X PF00388.19 KFP21446.1 - 8.2e-66 220.0 0.4 2e-65 218.8 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 KFP21446.1 - 7.7e-48 160.5 0.1 2e-24 85.4 0.0 3.0 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 KFP21446.1 - 1.4e-39 135.0 0.0 3.5e-39 133.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.28 KFP21446.1 - 4.1e-16 58.3 0.6 1.2e-15 56.9 0.6 1.9 1 0 0 1 1 1 1 SH3 domain C2 PF00168.30 KFP21446.1 - 2.3e-14 53.5 0.0 6.5e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KFP21446.1 - 9.8e-12 45.3 0.0 0.012 16.1 0.0 4.0 4 0 0 4 4 3 3 PH domain SH3_9 PF14604.6 KFP21446.1 - 2.7e-10 40.0 0.1 2.7e-10 40.0 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KFP21446.1 - 6.4e-09 35.4 0.1 1.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GDPD PF03009.17 KFP21446.1 - 0.00033 20.5 0.0 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PH_12 PF16457.5 KFP21446.1 - 0.0063 17.0 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_6 PF13405.6 KFP21446.1 - 0.12 12.4 0.0 2.7 8.1 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain Homeodomain PF00046.29 KFP21447.1 - 8.7e-27 92.7 14.7 2e-08 33.9 0.7 4.4 4 0 0 4 4 4 4 Homeodomain zf_C2H2_ZHX PF18387.1 KFP21447.1 - 6.5e-26 89.7 1.6 6.5e-26 89.7 1.6 2.3 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain Homeobox_KN PF05920.11 KFP21447.1 - 9.3e-15 54.3 3.4 0.0023 17.8 0.1 4.2 4 0 0 4 4 4 3 Homeobox KN domain Homez PF11569.8 KFP21447.1 - 3.1e-07 29.7 0.0 0.088 12.3 0.0 4.0 4 0 0 4 4 4 2 Homeodomain leucine-zipper encoding, Homez LNS2 PF08235.13 KFP21448.1 - 4.9e-106 353.3 0.0 7.8e-106 352.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFP21448.1 - 1.9e-43 146.6 0.0 3.3e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KFP21448.1 - 3.8e-34 116.9 0.0 7.5e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF3827 PF12877.7 KFP21448.1 - 0.53 8.6 2.5 0.71 8.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EMI PF07546.13 KFP21449.1 - 2.6e-16 60.1 5.8 2.6e-16 60.1 5.8 1.9 2 0 0 2 2 1 1 EMI domain DUF1664 PF07889.12 KFP21449.1 - 8e-08 32.4 20.0 0.015 15.3 1.6 7.3 4 2 4 9 9 9 2 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KFP21449.1 - 6.8e-06 26.4 20.5 0.44 10.8 0.2 7.0 4 2 1 5 5 5 2 Domain of unknown function (DUF5082) Spc7 PF08317.11 KFP21449.1 - 2.8e-05 23.2 18.8 0.042 12.7 0.0 4.6 3 1 1 4 4 4 2 Spc7 kinetochore protein Apolipoprotein PF01442.18 KFP21449.1 - 8.2e-05 22.6 15.7 0.15 11.9 1.3 5.7 2 1 2 5 5 5 3 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 KFP21449.1 - 0.00012 22.3 23.2 0.017 15.3 3.8 6.5 3 2 2 5 5 5 2 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KFP21449.1 - 0.00037 20.5 16.3 7.5 6.6 3.7 6.7 2 1 6 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFP21449.1 - 0.00092 19.6 15.2 20 5.7 0.8 8.1 7 2 2 9 9 7 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 KFP21449.1 - 0.0011 18.4 4.5 0.0011 18.4 4.5 3.9 3 2 0 4 4 4 1 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.6 KFP21449.1 - 0.0018 18.6 20.8 2.4 8.6 0.0 6.8 7 1 0 7 7 6 1 Snapin/Pallidin Exonuc_VII_L PF02601.15 KFP21449.1 - 0.0035 17.0 8.3 0.87 9.1 0.1 3.3 2 1 0 2 2 2 2 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 KFP21449.1 - 0.0045 16.6 13.3 0.012 15.2 2.4 4.8 3 1 1 5 5 5 1 fzo-like conserved region MIP-T3_C PF17749.1 KFP21449.1 - 0.0055 16.7 15.4 1.4 8.8 0.2 5.4 5 1 2 7 7 6 1 Microtubule-binding protein MIP-T3 C-terminal region Golgin_A5 PF09787.9 KFP21449.1 - 0.0091 15.5 2.5 0.0091 15.5 2.5 4.1 3 1 2 5 5 5 1 Golgin subfamily A member 5 DASH_Dam1 PF08653.10 KFP21449.1 - 0.018 14.8 4.1 56 3.7 0.0 6.2 6 0 0 6 6 6 0 DASH complex subunit Dam1 Sugarporin_N PF11471.8 KFP21449.1 - 0.036 14.0 0.1 0.17 11.8 0.1 2.2 2 0 0 2 2 1 0 Maltoporin periplasmic N-terminal extension Corona_S2 PF01601.16 KFP21449.1 - 0.043 12.3 6.8 0.9 8.0 0.2 3.6 2 2 2 4 4 4 0 Coronavirus S2 glycoprotein WXG100 PF06013.12 KFP21449.1 - 0.073 13.3 9.8 2.7 8.3 0.0 7.1 7 3 2 9 9 8 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 KFP21449.1 - 0.099 13.0 23.4 30 5.1 0.1 9.9 7 3 4 11 11 10 0 Flagella accessory protein C (FlaC) Trimer_CC PF08954.11 KFP21449.1 - 0.1 12.2 8.8 2.2 7.9 0.2 4.2 4 0 0 4 4 3 0 Trimerisation motif OmpH PF03938.14 KFP21449.1 - 0.17 12.2 5.0 33 4.8 0.0 4.2 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KFP21449.1 - 0.2 11.7 29.4 0.018 15.1 3.5 6.3 5 2 0 7 7 6 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 KFP21449.1 - 0.2 12.0 20.1 17 5.8 0.2 7.4 5 3 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KFP21449.1 - 0.24 11.9 18.7 10 6.7 1.1 6.2 5 3 1 6 6 6 0 Protein of unknown function DUF16 HCMV_UL139 PF12507.8 KFP21449.1 - 0.28 11.6 6.9 7 7.1 0.1 4.0 4 1 1 5 5 5 0 Human Cytomegalovirus UL139 protein TACC_C PF05010.14 KFP21449.1 - 0.35 10.6 13.7 0.59 9.9 1.1 3.6 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Bacillus_HBL PF05791.11 KFP21449.1 - 0.74 9.6 9.6 15 5.4 1.3 4.9 3 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.11 KFP21449.1 - 1.8 8.6 18.3 0.61 10.2 0.7 6.1 4 3 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.9 KFP21449.1 - 5.8 7.1 23.9 2.8 8.1 2.8 5.3 3 1 2 5 5 5 0 JNK_SAPK-associated protein-1 Tropomyosin PF00261.20 KFP21449.1 - 6.9 6.0 19.1 0.24 10.7 5.3 4.2 2 1 1 3 3 3 0 Tropomyosin Fez1 PF06818.15 KFP21449.1 - 7.4 7.0 23.9 5 7.5 2.6 4.7 2 1 2 4 4 3 0 Fez1 Ribophorin_II PF05817.14 KFP21450.1 - 5.6e-217 722.2 7.3 6.3e-217 722.1 7.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Hormone_2 PF00123.20 KFP21451.1 - 4.8e-15 55.2 0.2 3.4e-14 52.4 0.1 2.1 2 0 0 2 2 2 1 Peptide hormone UPF0239 PF06783.11 KFP21453.1 - 1.5e-24 85.9 0.0 1.8e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) BC10 PF06726.12 KFP21454.1 - 5.3e-27 93.8 10.2 6.8e-27 93.5 10.2 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Gpi16 PF04113.14 KFP21455.1 - 1.6e-145 485.7 2.2 2.2e-144 482.0 2.2 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Dysbindin PF04440.16 KFP21456.1 - 2.4e-49 167.2 6.6 2.9e-49 167.0 6.6 1.1 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Filament PF00038.21 KFP21457.1 - 3e-117 391.6 23.4 3.4e-117 391.5 23.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF4407 PF14362.6 KFP21457.1 - 0.0036 16.7 16.2 0.15 11.4 8.2 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4407) DivIC PF04977.15 KFP21457.1 - 0.0047 16.7 18.1 0.2 11.5 0.9 4.6 4 0 0 4 4 4 2 Septum formation initiator POX PF07526.11 KFP21457.1 - 0.028 15.0 0.2 0.3 11.6 0.8 2.2 2 1 0 2 2 2 0 Associated with HOX SAA PF00277.18 KFP21457.1 - 0.064 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Serum amyloid A protein TPR_MLP1_2 PF07926.12 KFP21457.1 - 0.071 13.2 0.2 0.071 13.2 0.2 4.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KFP21457.1 - 0.7 10.4 29.4 0.33 11.5 0.8 3.9 3 1 1 4 4 4 0 Apg6 coiled-coil region Sec2p PF06428.11 KFP21457.1 - 0.7 9.9 0.1 0.7 9.9 0.1 4.6 3 2 2 5 5 5 0 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 KFP21457.1 - 0.73 9.8 19.1 3.5 7.6 0.0 4.7 3 1 1 4 4 4 0 Prefoldin subunit Bacillus_HBL PF05791.11 KFP21457.1 - 0.8 9.5 13.4 0.027 14.3 3.1 3.3 3 2 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 KFP21457.1 - 0.85 9.9 20.4 3.9 7.8 5.0 4.3 3 1 0 4 4 4 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KFP21457.1 - 1.1 9.4 14.2 12 5.9 1.7 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KFP21457.1 - 1.1 8.9 25.7 0.34 10.6 4.9 3.9 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KFP21457.1 - 1.5 9.0 14.8 35 4.5 0.1 4.0 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KFP21457.1 - 1.5 7.6 24.8 2 7.2 3.9 3.0 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4446 PF14584.6 KFP21457.1 - 1.8 8.5 11.9 2.3 8.2 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) SlyX PF04102.12 KFP21457.1 - 2.2 8.9 23.5 8.8 7.0 0.0 5.3 4 1 2 6 6 5 0 SlyX DHR10 PF18595.1 KFP21457.1 - 2.8 8.0 31.6 1 9.4 2.3 4.8 4 2 1 5 5 5 0 Designed helical repeat protein 10 domain Prefoldin PF02996.17 KFP21457.1 - 2.9 7.8 17.6 0.67 9.9 5.9 4.3 3 2 1 4 4 4 0 Prefoldin subunit UPF0242 PF06785.11 KFP21457.1 - 5.8 7.0 22.2 6.6 6.8 10.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KFP21457.1 - 6.4 7.3 12.9 39 4.8 0.2 3.9 3 1 1 4 4 4 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 KFP21457.1 - 8.2 6.5 28.7 5.7 7.0 1.7 4.8 3 2 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KFP21458.1 - 6.2e-118 393.9 32.5 7e-118 393.7 32.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein Atg14 PF10186.9 KFP21458.1 - 6.6e-06 25.4 7.9 0.00025 20.2 0.4 2.4 2 1 1 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KFP21458.1 - 2.6e-05 24.3 1.2 2.6e-05 24.3 1.2 3.8 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KFP21458.1 - 0.00023 20.6 17.5 0.0039 16.6 9.7 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) APG6_N PF17675.1 KFP21458.1 - 0.013 16.0 5.7 0.013 16.0 5.7 4.0 2 2 0 3 3 3 0 Apg6 coiled-coil region SPATA1_C PF15743.5 KFP21458.1 - 0.019 15.0 0.1 0.019 15.0 0.1 4.0 3 1 0 3 3 3 0 Spermatogenesis-associated C-terminus BRE1 PF08647.11 KFP21458.1 - 0.029 14.4 2.0 0.029 14.4 2.0 4.1 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase DUF1192 PF06698.11 KFP21458.1 - 0.059 13.4 6.0 4.7 7.4 1.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Fib_alpha PF08702.10 KFP21458.1 - 0.098 12.8 21.1 8.3 6.6 0.8 4.3 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KFP21458.1 - 0.16 12.1 24.1 1.8 8.7 2.2 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KFP21458.1 - 0.31 10.8 26.5 1.4 8.7 0.4 5.0 5 0 0 5 5 5 0 Septum formation initiator ATG16 PF08614.11 KFP21458.1 - 0.32 11.2 29.5 4.9 7.3 5.0 3.9 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 KFP21458.1 - 0.5 10.2 13.5 1 9.1 0.5 3.5 3 1 0 3 3 3 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.12 KFP21458.1 - 0.6 10.2 14.8 1 9.4 0.6 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 KFP21458.1 - 0.65 9.4 24.7 6.3 6.2 14.8 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 SlyX PF04102.12 KFP21458.1 - 0.71 10.5 27.6 0.5 11.0 1.5 5.4 3 1 2 5 5 5 0 SlyX Prefoldin PF02996.17 KFP21458.1 - 1.4 8.8 16.4 2 8.3 1.7 4.0 4 0 0 4 4 4 0 Prefoldin subunit DUF724 PF05266.14 KFP21458.1 - 1.5 8.6 17.0 2.1 8.1 0.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 KFP21458.1 - 1.5 8.8 15.1 4 7.4 0.0 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF4446) Spc7 PF08317.11 KFP21458.1 - 2 7.2 26.5 0.15 10.9 11.5 2.6 2 1 0 3 3 3 0 Spc7 kinetochore protein JIP_LZII PF16471.5 KFP21458.1 - 2.1 8.6 21.9 0.14 12.3 0.6 4.0 5 0 0 5 5 3 0 JNK-interacting protein leucine zipper II Exonuc_VII_L PF02601.15 KFP21458.1 - 2.2 7.8 17.5 53 3.2 17.5 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 KFP21458.1 - 2.9 8.0 16.9 5.8 7.0 1.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KFP21458.1 - 2.9 7.9 31.0 3.5 7.6 9.3 4.3 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 KFP21458.1 - 3.6 7.6 17.7 4.1 7.4 0.3 3.3 2 1 2 4 4 4 0 FlxA-like protein FlaC_arch PF05377.11 KFP21458.1 - 4.2 7.8 20.8 4.2 7.8 1.7 4.6 5 1 0 5 5 4 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 KFP21458.1 - 5.3 6.7 29.9 69 3.0 25.6 3.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 KFP21458.1 - 8.8 6.5 27.4 11 6.2 6.8 3.6 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 Filament PF00038.21 KFP21459.1 - 2.8e-27 96.1 26.1 4.2e-27 95.5 23.8 1.9 2 0 0 2 2 2 1 Intermediate filament protein V_ATPase_I PF01496.19 KFP21459.1 - 0.17 9.7 9.4 0.24 9.3 9.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family U3_assoc_6 PF08640.11 KFP21459.1 - 0.41 10.8 10.9 0.17 11.9 0.9 2.8 1 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 FUSC PF04632.12 KFP21459.1 - 0.61 8.5 7.7 0.79 8.2 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 KFP21459.1 - 1.4 9.0 18.7 0.32 11.1 15.0 1.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KFP21459.1 - 2.4 8.2 10.7 0.1 12.6 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 KFP21459.1 - 5.3 7.6 9.0 15 6.1 1.7 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 KFP21459.1 - 6 6.9 21.5 14 5.8 8.9 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein NuA4 PF09340.10 KFP21459.1 - 9.6 6.2 9.2 11 5.9 1.5 3.2 2 1 1 3 3 3 0 Histone acetyltransferase subunit NuA4 HMG_box PF00505.19 KFP21460.1 - 3.1e-18 65.9 1.7 3.1e-18 65.9 1.7 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFP21460.1 - 4.6e-06 27.1 0.6 4.6e-06 27.1 0.6 2.5 2 0 0 2 2 2 1 HMG-box domain Pepsin-I3 PF06394.13 KFP21460.1 - 0.31 11.2 0.2 0.31 11.2 0.2 2.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DNA_topoisoIV PF00521.20 KFP21461.1 - 1.6e-134 449.1 0.3 5.3e-134 447.3 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFP21461.1 - 8.4e-49 165.1 7.8 8.4e-49 165.1 7.8 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFP21461.1 - 7.4e-29 100.4 1.2 1.9e-28 99.1 1.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFP21461.1 - 5.1e-16 59.2 0.0 1.7e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFP21461.1 - 1.6e-09 37.9 0.0 4.4e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Pannexin_like PF12534.8 KFP21462.1 - 1.5e-157 524.2 6.9 2.2e-157 523.6 6.9 1.3 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 LRR_8 PF13855.6 KFP21462.1 - 6.4e-33 112.3 32.3 7.5e-10 38.4 1.7 7.4 2 2 8 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KFP21462.1 - 8.6e-24 83.2 38.9 5.7e-06 26.6 1.4 9.0 4 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP21462.1 - 7.1e-11 41.9 13.9 7.3e-06 25.6 1.8 3.6 1 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KFP21462.1 - 1.3e-05 25.1 34.1 0.35 11.6 0.1 10.6 10 2 0 10 10 10 3 Leucine Rich Repeat AKAP95 PF04988.12 KFP21463.1 - 2.8e-67 226.0 14.1 5.2e-67 225.2 14.1 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 KFP21463.1 - 0.035 14.4 9.9 0.8 10.1 1.4 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF678 PF05077.12 KFP21463.1 - 0.069 13.3 0.4 4.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-Di19 PF05605.12 KFP21463.1 - 0.16 12.3 8.0 0.78 10.1 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Eapp_C PF10238.9 KFP21463.1 - 1.8 8.6 10.6 0.78 9.8 3.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-C2H2_4 PF13894.6 KFP21464.1 - 2.2e-17 62.2 47.6 0.00093 19.8 0.3 9.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP21464.1 - 9.9e-05 22.6 56.1 0.00034 20.9 0.5 9.0 8 1 0 8 8 8 4 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KFP21464.1 - 0.0012 18.4 15.0 0.15 11.7 0.6 5.0 5 0 0 5 5 5 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KFP21464.1 - 0.069 13.5 19.4 0.92 9.9 0.0 6.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_7 PF15269.6 KFP21464.1 - 0.21 11.7 24.2 0.19 11.8 3.0 5.3 4 1 1 5 5 5 0 Zinc-finger Metallothio_Pro PF02069.16 KFP21464.1 - 0.37 11.0 5.0 1.7 9.0 5.0 2.2 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-C2H2_8 PF15909.5 KFP21464.1 - 1 9.7 20.6 0.64 10.4 4.1 4.4 2 1 1 3 3 3 0 C2H2-type zinc ribbon Glutaredoxin PF00462.24 KFP21464.1 - 1.8 8.9 4.8 17 5.7 0.3 3.7 4 0 0 4 4 4 0 Glutaredoxin FYVE PF01363.21 KFP21464.1 - 5.6 7.2 19.5 0.92 9.7 5.7 5.4 5 1 0 5 5 5 0 FYVE zinc finger VCBS PF13517.6 KFP21465.1 - 5.1e-30 103.9 15.9 5.7e-11 42.8 1.7 5.0 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 KFP21465.1 - 8.9e-14 51.2 0.0 1.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 KFP21465.1 - 5.1e-12 45.7 19.6 0.0028 17.8 0.4 5.2 5 0 0 5 5 5 4 FG-GAP repeat EGF_CA PF07645.15 KFP21465.1 - 7.2e-11 42.1 5.7 7.2e-11 42.1 5.7 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 KFP21465.1 - 0.011 15.6 9.1 0.25 11.3 1.7 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like Dockerin_1 PF00404.18 KFP21465.1 - 0.25 11.6 3.6 32 4.8 0.1 3.8 4 0 0 4 4 4 0 Dockerin type I domain Erf4 PF10256.9 KFP21466.1 - 7.1e-33 113.2 0.0 8.1e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fz PF01392.22 KFP21467.1 - 2.4e-15 57.1 2.2 2.4e-15 57.1 2.2 1.8 2 0 0 2 2 2 1 Fz domain NTR PF01759.21 KFP21467.1 - 7.7e-15 54.6 0.1 1.1e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.17 KFP21467.1 - 0.038 13.8 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase PI3_PI4_kinase PF00454.27 KFP21468.1 - 8.3e-63 212.5 0.0 9.8e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MORN PF02493.20 KFP21469.1 - 7.7e-28 94.7 20.1 3.4e-08 32.9 0.3 5.7 6 0 0 6 6 6 4 MORN repeat HCBP_related PF06594.11 KFP21469.1 - 0.054 13.5 1.0 0.2 11.6 0.1 2.3 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Rib PF08428.10 KFP21469.1 - 0.055 13.5 0.1 20 5.2 0.0 2.9 3 0 0 3 3 3 0 Rib/alpha-like repeat UBD PF16455.5 KFP21470.1 - 1.1e-37 128.4 0.0 1.8e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFP21470.1 - 8e-15 54.4 0.1 1.4e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFP21470.1 - 0.00021 21.1 0.1 0.00031 20.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DHHC PF01529.20 KFP21471.1 - 1.2e-24 86.9 22.6 1.2e-24 86.9 22.6 3.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase EXOSC1 PF10447.9 KFP21472.1 - 3.6e-14 53.3 1.1 2.2e-12 47.6 0.2 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Pkinase_Tyr PF07714.17 KFP21473.1 - 1e-24 87.3 0.5 2.1e-24 86.2 0.5 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP21473.1 - 1.2e-24 87.1 1.7 3.2e-24 85.7 1.7 1.7 1 1 0 1 1 1 1 Protein kinase domain OSR1_C PF12202.8 KFP21473.1 - 0.096 12.9 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain PRESAN PF09687.10 KFP21473.1 - 0.12 13.0 7.8 0.41 11.2 7.3 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal PP2C PF00481.21 KFP21474.1 - 8.7e-69 232.0 1.1 2.7e-57 194.3 0.4 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KFP21474.1 - 0.0057 16.3 0.0 0.03 14.0 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C zf-H2C2_2 PF13465.6 KFP21475.1 - 1.9e-29 100.8 48.6 2.2e-09 37.3 1.1 6.5 6 1 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFP21475.1 - 6.4e-23 80.2 47.5 8.4e-07 28.6 0.0 5.7 5 1 0 5 5 5 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFP21475.1 - 9.5e-17 60.4 47.6 0.00065 20.0 2.4 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21475.1 - 4.6e-12 45.7 41.3 0.0085 16.8 3.9 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger GAGA PF09237.11 KFP21475.1 - 0.00021 21.0 16.9 0.017 14.9 0.6 3.6 1 1 2 3 3 3 2 GAGA factor zf-C2HE PF16278.5 KFP21475.1 - 0.00079 19.8 30.3 0.018 15.5 1.5 4.7 2 2 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_7 PF15269.6 KFP21475.1 - 0.047 13.8 2.1 0.047 13.8 2.1 5.0 1 1 4 5 5 5 0 Zinc-finger zf-C2H2_2 PF12756.7 KFP21475.1 - 0.35 11.2 25.1 0.3 11.5 8.2 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 KFP21475.1 - 0.75 10.3 30.3 3.4 8.2 0.2 5.0 3 1 2 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D PhnJ PF06007.11 KFP21475.1 - 2.6 7.0 4.4 9.5 5.1 0.2 2.3 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnJ Zn_Tnp_IS1595 PF12760.7 KFP21475.1 - 4.1 7.5 19.4 5.4 7.1 5.9 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 KFP21475.1 - 5.9 6.9 16.7 1.2 9.1 0.5 3.9 3 1 1 4 4 3 0 RNA polymerases M/15 Kd subunit NOA36 PF06524.12 KFP21475.1 - 9.6 5.4 15.2 0.081 12.2 1.2 2.3 1 1 0 2 2 2 0 NOA36 protein SNX17_FERM_C PF18116.1 KFP21476.1 - 4.9e-17 61.9 0.2 2.9e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 Sorting Nexin 17 FERM C-terminal domain PX PF00787.24 KFP21476.1 - 3.5e-06 27.0 0.0 1.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 PX domain DUF5393 PF17371.2 KFP21476.1 - 0.071 11.2 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) RA PF00788.23 KFP21476.1 - 0.075 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 KFP21476.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 FERM N-terminal domain E1-E2_ATPase PF00122.20 KFP21477.1 - 8.8e-24 84.0 0.8 9.7e-24 83.9 0.8 1.0 1 0 0 1 1 1 1 E1-E2 ATPase Ldl_recept_b PF00058.17 KFP21478.1 - 3.1e-31 107.6 3.0 1.6e-11 44.5 0.1 4.1 3 1 0 3 3 3 3 Low-density lipoprotein receptor repeat class B cEGF PF12662.7 KFP21478.1 - 8.8e-07 28.7 1.6 8.8e-07 28.7 1.6 2.3 2 0 0 2 2 2 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KFP21478.1 - 1.3e-06 28.6 17.3 0.00016 21.9 4.3 2.3 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP21478.1 - 5.8e-06 26.4 21.8 0.00013 22.1 7.9 2.3 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF_3 PF12947.7 KFP21478.1 - 8.2e-06 25.9 13.5 0.0014 18.8 2.4 2.5 2 0 0 2 2 2 2 EGF domain SGL PF08450.12 KFP21478.1 - 0.012 15.2 0.2 0.07 12.7 0.2 2.0 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region EGF_MSP1_1 PF12946.7 KFP21478.1 - 0.033 14.2 2.3 0.033 14.2 2.3 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 Ldl_recept_b PF00058.17 KFP21479.1 - 2.1e-31 108.1 4.8 3.1e-11 43.6 0.0 4.0 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KFP21479.1 - 0.00012 21.7 0.2 0.0008 19.1 0.0 1.9 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Tetraspanin PF00335.20 KFP21480.1 - 6.4e-28 98.0 10.8 8.2e-28 97.7 10.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Alfin PF12165.8 KFP21480.1 - 0.042 13.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Alfin DUF1218 PF06749.12 KFP21480.1 - 0.11 13.0 2.4 4.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) ArfGap PF01412.18 KFP21480.1 - 0.46 10.6 4.1 1.1 9.4 4.1 1.7 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf zf-UBR PF02207.20 KFP21481.1 - 2.5e-21 75.6 11.7 2.5e-21 75.6 11.7 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KFP21481.1 - 1.1e-17 63.6 0.1 2.7e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Metallophos PF00149.28 KFP21482.1 - 3.2e-10 40.9 0.0 6.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Big_7 PF17957.1 KFP21482.1 - 0.00078 20.2 0.4 0.011 16.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial Ig domain DUF4896 PF16237.5 KFP21482.1 - 0.27 11.1 3.7 1.3 8.9 3.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) ADH_N_2 PF16884.5 KFP21483.1 - 1.2e-25 89.5 0.0 2.3e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFP21483.1 - 5.3e-15 55.6 0.0 8.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFP21483.1 - 4e-14 53.8 0.0 1.8e-13 51.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Orthopox_F14 PF06076.12 KFP21483.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus F14 protein ELM2 PF01448.24 KFP21484.1 - 1.2e-09 38.7 2.4 2.9e-09 37.5 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.31 KFP21484.1 - 0.00064 19.9 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain LRR_4 PF12799.7 KFP21485.1 - 2.2e-14 53.3 11.7 1.9e-05 24.9 6.4 3.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFP21485.1 - 9.9e-09 34.9 2.5 9.1e-06 25.3 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KFP21485.1 - 4.2e-07 29.6 10.2 0.012 15.4 3.9 3.7 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFP21485.1 - 0.59 10.3 4.7 6 7.2 0.3 3.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KFP21485.1 - 3.5 8.5 15.0 47 5.1 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat Cupin_4 PF08007.12 KFP21486.1 - 1.5e-56 192.2 0.0 1.8e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KFP21486.1 - 2.1e-05 24.3 0.0 0.0014 18.4 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KFP21486.1 - 0.013 15.2 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Cupin domain PID PF00640.23 KFP21487.1 - 9.1e-35 119.7 0.1 1.5e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 KFP21487.1 - 2.3e-31 108.2 1.6 2.6e-30 104.8 0.6 2.8 2 0 0 2 2 2 1 NUMB domain PTB PF08416.13 KFP21487.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP21487.1 - 3.7e-05 23.7 0.2 6.3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PWI PF01480.17 KFP21488.1 - 3.4e-14 52.9 0.2 7.6e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KFP21488.1 - 4.3e-09 36.1 0.0 8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.21 KFP21489.1 - 3.2e-16 59.2 6.1 3.2e-16 59.2 6.1 5.0 5 1 1 6 6 6 1 FYVE zinc finger AIG1 PF04548.16 KFP21489.1 - 0.002 17.5 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GBP PF02263.19 KFP21489.1 - 0.0029 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain ANAPC4_WD40 PF12894.7 KFP21490.1 - 0.0064 16.8 0.0 0.063 13.6 0.1 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP21490.1 - 0.0093 16.8 0.1 10 7.1 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 KFP21490.1 - 0.03 13.0 0.1 0.17 10.5 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Requiem_N PF14051.6 KFP21491.1 - 2.5e-37 126.9 0.4 5.2e-37 125.9 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 KFP21491.1 - 5.2e-22 77.5 23.4 3.7e-12 45.9 5.2 3.3 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 KFP21491.1 - 0.011 15.8 9.3 0.011 15.8 9.3 3.6 2 1 1 3 3 2 0 PHD-finger Lar_restr_allev PF14354.6 KFP21491.1 - 0.017 15.5 1.4 0.017 15.5 1.4 4.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-PHD-like PF15446.6 KFP21491.1 - 0.033 13.8 10.5 0.14 11.7 2.0 2.7 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-C2H2 PF00096.26 KFP21491.1 - 0.045 14.2 0.2 0.045 14.2 0.2 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21491.1 - 0.05 14.5 0.2 0.05 14.5 0.2 5.4 5 1 1 6 6 6 0 C2H2-type zinc finger C1_1 PF00130.22 KFP21491.1 - 0.066 13.1 20.2 0.42 10.5 0.4 4.6 3 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KFP21491.1 - 0.44 10.5 21.5 0.46 10.4 0.5 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KFP21491.1 - 1 9.0 20.3 0.078 12.6 1.2 3.9 3 1 1 4 4 4 0 PHD-finger zf-RING_7 PF02591.15 KFP21491.1 - 1.5 9.1 8.6 11 6.3 0.8 3.6 3 1 0 3 3 3 0 C4-type zinc ribbon domain zf-BED PF02892.15 KFP21491.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.3 3 1 0 3 3 3 0 BED zinc finger zf-met PF12874.7 KFP21491.1 - 2.6 8.6 0.0 2.6 8.6 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zf_RING PF16744.5 KFP21491.1 - 4.6 7.4 21.6 12 6.1 5.0 4.8 3 1 1 4 4 4 0 KIAA1045 RING finger RGS_DHEX PF18148.1 KFP21492.1 - 2.2e-50 168.9 1.8 7.7e-50 167.1 1.8 2.0 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP21492.1 - 3.5e-34 117.6 0.4 3.5e-34 117.6 0.4 2.4 2 1 1 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 KFP21492.1 - 4.1e-17 62.0 0.0 1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFP21492.1 - 9.1e-12 44.8 0.1 2.3e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.11 KFP21492.1 - 0.023 14.4 0.4 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Lactamase_B_6 PF16661.5 KFP21493.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Ras PF00071.22 KFP21494.1 - 3.1e-49 166.7 0.2 3.5e-49 166.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21494.1 - 3.7e-18 65.9 0.0 5.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP21494.1 - 3e-07 30.1 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP21494.1 - 2.2e-05 24.4 1.5 0.084 12.8 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFP21494.1 - 0.0002 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFP21494.1 - 0.0011 18.4 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFP21494.1 - 0.0032 17.0 0.1 0.0067 16.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KFP21494.1 - 0.0065 16.5 0.1 0.036 14.1 0.0 1.9 1 1 1 2 2 2 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KFP21494.1 - 0.037 13.6 0.3 0.17 11.4 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 KFP21494.1 - 0.057 13.3 0.2 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KFP21494.1 - 0.061 13.7 0.1 0.1 13.0 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFP21494.1 - 0.066 12.9 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFP21494.1 - 0.074 13.3 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFP21494.1 - 0.11 12.7 0.1 0.55 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zip PF02535.22 KFP21495.1 - 6.1e-50 170.3 9.9 1.4e-49 169.1 9.9 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter TPR_1 PF00515.28 KFP21496.1 - 1.1e-27 94.7 7.2 3.4e-10 39.3 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFP21496.1 - 1.4e-22 79.3 0.7 5.7e-22 77.3 0.1 2.1 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 KFP21496.1 - 9.8e-20 69.0 5.7 4.9e-06 26.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP21496.1 - 1.1e-19 68.9 3.6 2e-07 30.6 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP21496.1 - 4.6e-17 61.4 6.3 5.1e-07 29.3 0.3 4.1 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 KFP21496.1 - 1.8e-14 53.0 3.5 1.7e-06 28.0 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP21496.1 - 5.4e-12 44.8 0.3 0.0011 18.8 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP21496.1 - 2.8e-10 40.1 0.0 0.017 15.9 0.0 4.3 3 1 2 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP21496.1 - 1.2e-09 38.7 1.3 1.8e-05 25.3 0.1 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP21496.1 - 1.1e-08 35.3 2.2 4.9e-07 29.9 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP21496.1 - 1.9e-08 34.7 2.6 2.3e-05 24.8 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP21496.1 - 2.3e-08 33.6 3.0 0.009 15.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP21496.1 - 6.9e-05 22.9 0.0 0.0014 18.8 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.12 KFP21496.1 - 7.3e-05 22.6 0.8 0.28 10.9 0.1 3.0 2 1 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 KFP21496.1 - 0.00016 21.7 5.4 0.05 13.7 0.1 3.4 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KFP21496.1 - 0.00018 21.9 0.7 1.2 10.0 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.8 KFP21496.1 - 0.0028 16.6 0.3 1.5 7.7 0.3 2.2 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 DUF627 PF04781.12 KFP21496.1 - 0.0037 17.2 0.2 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF627) BTAD PF03704.17 KFP21496.1 - 0.0053 17.2 0.8 0.46 10.9 0.1 2.5 2 1 1 3 3 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 KFP21496.1 - 0.0065 15.7 0.0 1.6 7.9 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KFP21496.1 - 0.12 12.5 8.5 10 6.3 0.2 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.11 KFP21496.1 - 0.12 12.1 9.6 0.9 9.3 3.7 2.8 2 0 0 2 2 2 0 XPC-binding domain TrbI PF03743.14 KFP21496.1 - 0.42 10.4 3.3 0.62 9.9 3.3 1.4 1 1 0 1 1 1 0 Bacterial conjugation TrbI-like protein STI1 PF17830.1 KFP21496.1 - 0.63 10.0 5.5 0.35 10.8 0.6 2.6 2 0 0 2 2 2 0 STI1 domain Peptidase_M3 PF01432.20 KFP21497.1 - 4.4e-164 547.1 0.1 5.6e-164 546.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 CdvA PF18822.1 KFP21497.1 - 0.33 10.8 4.3 0.12 12.2 1.0 1.9 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF4085 PF13315.6 KFP21497.1 - 0.51 9.9 3.2 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Keratin PF02422.16 KFP21498.1 - 3.4e-33 113.2 9.4 4e-33 113.0 9.4 1.0 1 0 0 1 1 1 1 Keratin Histone PF00125.24 KFP21499.1 - 1.6e-25 90.0 0.4 1.9e-25 89.7 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFP21499.1 - 7.6e-07 29.3 0.8 1.5e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFP21499.1 - 0.0025 18.3 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KFP21499.1 - 0.0041 17.2 0.7 0.0047 17.0 0.7 1.2 1 0 0 1 1 1 1 YscO-like protein Wbp11 PF09429.10 KFP21500.1 - 1.6e-22 79.7 13.8 1.6e-22 79.7 13.8 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 MHB PF16525.5 KFP21500.1 - 0.17 12.1 0.5 2.7 8.3 0.1 2.4 1 1 1 2 2 2 0 Haemophore, haem-binding TEX12 PF15219.6 KFP21500.1 - 0.72 10.2 2.8 4.1 7.8 0.1 2.3 1 1 1 2 2 2 0 Testis-expressed 12 DUF4533 PF15047.6 KFP21501.1 - 6.3e-65 218.9 5.9 3.6e-63 213.2 5.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4533) DNA_repr_REX1B PF14966.6 KFP21501.1 - 0.042 14.5 1.4 0.39 11.4 0.1 2.4 2 1 1 3 3 3 0 DNA repair REX1-B DUF4533 PF15047.6 KFP21502.1 - 1.1e-28 100.4 0.3 1.3e-28 100.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) ART PF01129.18 KFP21503.1 - 6.2e-51 172.8 1.8 7e-51 172.6 1.8 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 KFP21503.1 - 0.00081 18.8 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme YchF-GTPase_C PF06071.13 KFP21503.1 - 0.022 15.0 0.1 0.042 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) PKcGMP_CC PF16808.5 KFP21505.1 - 0.23 11.4 3.9 0.34 10.8 3.9 1.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Thioredoxin_6 PF13848.6 KFP21506.1 - 9.1e-23 81.1 0.2 9.8e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain Rho_GDI PF02115.17 KFP21507.1 - 3.2e-76 255.5 0.2 3.7e-76 255.3 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PDE6_gamma PF04868.12 KFP21508.1 - 6.1e-47 157.8 0.9 6.7e-47 157.7 0.9 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit TM140 PF14985.6 KFP21509.1 - 3.1e-23 82.2 1.3 3.8e-23 82.0 1.3 1.1 1 0 0 1 1 1 1 TM140 protein family WD40 PF00400.32 KFP21510.1 - 1.2e-12 48.0 5.7 0.0032 18.3 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21510.1 - 1.1e-08 35.3 0.0 0.00021 21.5 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP21510.1 - 7.8e-05 21.8 0.1 0.00039 19.5 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4313 PF14190.6 KFP21510.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Xan_ur_permease PF00860.20 KFP21511.1 - 1.6e-90 303.7 24.7 2e-90 303.3 24.7 1.1 1 0 0 1 1 1 1 Permease family zf-RING_4 PF14570.6 KFP21512.1 - 3.5e-20 71.5 12.2 6.2e-20 70.7 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFP21512.1 - 1.7e-06 27.8 7.4 3.3e-06 26.8 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFP21512.1 - 8.4e-06 25.5 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KFP21512.1 - 0.0035 17.7 11.0 0.0077 16.5 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP21512.1 - 0.028 14.3 10.4 0.062 13.2 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP21512.1 - 0.035 14.0 9.9 0.075 12.9 9.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 KFP21512.1 - 0.053 13.6 3.6 0.14 12.3 3.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 KFP21512.1 - 0.43 10.6 8.9 0.84 9.7 8.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KFP21512.1 - 1.8 8.5 9.7 48 3.9 9.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nup192 PF11894.8 KFP21513.1 - 0 1301.2 11.0 0 1301.0 11.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Arf PF00025.21 KFP21514.1 - 1.5e-72 242.7 0.1 1.7e-72 242.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFP21514.1 - 7.2e-15 55.3 0.1 9.6e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP21514.1 - 3.5e-13 49.4 0.0 4.1e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFP21514.1 - 1.2e-10 41.1 0.0 1.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP21514.1 - 1.3e-10 41.0 0.7 1.2e-06 28.0 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFP21514.1 - 1.9e-10 40.4 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP21514.1 - 6.2e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KFP21514.1 - 0.0012 17.9 0.5 0.036 13.0 0.0 2.3 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFP21514.1 - 0.0027 17.3 0.3 0.021 14.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFP21514.1 - 0.0064 16.0 0.7 0.042 13.4 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 KFP21514.1 - 0.0084 15.9 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFP21514.1 - 0.02 15.4 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFP21514.1 - 0.042 14.4 0.2 0.12 12.9 0.2 1.9 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KFP21514.1 - 0.075 12.9 0.1 13 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFP21514.1 - 0.13 12.0 0.3 3.8 7.3 0.1 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KFP21514.1 - 0.13 12.4 0.0 1.9 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFP21514.1 - 0.14 11.7 0.2 8.1 6.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DRIM PF07539.12 KFP21515.1 - 4.1e-180 600.2 20.3 4.1e-180 600.2 20.3 2.8 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT_2 PF13646.6 KFP21515.1 - 0.0062 16.9 0.1 0.68 10.4 0.0 4.6 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 KFP21515.1 - 0.009 16.2 1.4 49 4.6 0.2 5.6 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 KFP21515.1 - 0.054 13.6 2.8 12 6.1 0.1 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Anoctamin PF04547.12 KFP21516.1 - 2.5e-162 540.8 13.0 3e-162 540.5 13.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KFP21516.1 - 3.8e-75 252.5 2.2 7e-75 251.6 2.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin GAS2 PF02187.17 KFP21517.1 - 3.1e-27 94.5 0.0 6.1e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KFP21517.1 - 6.1e-11 42.5 0.0 9.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-C4 PF00105.18 KFP21518.1 - 8.6e-29 99.8 14.7 8.6e-29 99.8 14.7 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP21518.1 - 1.4e-25 90.1 0.8 1.4e-25 90.1 0.8 2.4 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor MFS_1 PF07690.16 KFP21519.1 - 1.1e-46 159.4 30.9 1.4e-46 159.0 30.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1811 PF08838.10 KFP21519.1 - 0.19 12.0 2.4 0.41 10.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Pkinase PF00069.25 KFP21520.1 - 1.6e-26 93.3 0.0 3.1e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21520.1 - 3e-15 56.2 0.0 1.4e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase XRN_M PF17846.1 KFP21520.1 - 0.021 13.8 1.0 0.043 12.8 1.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain DEP PF00610.21 KFP21521.1 - 7.7e-19 67.5 0.9 3.4e-17 62.2 0.1 3.2 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2185 PF09951.9 KFP21521.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DUF1539 PF07560.11 KFP21521.1 - 3.5 7.7 7.1 16 5.6 0.7 3.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1539) Actin PF00022.19 KFP21522.1 - 4.6e-78 262.6 0.0 7.1e-77 258.7 0.0 1.9 1 1 0 1 1 1 1 Actin EcoRII-C PF09019.11 KFP21522.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal Chorein_N PF12624.7 KFP21523.1 - 8.2e-17 61.4 1.3 2.6e-15 56.6 0.0 3.7 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KFP21523.1 - 0.012 15.4 5.0 0.018 14.9 2.0 2.7 2 1 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal Csm1_N PF18504.1 KFP21523.1 - 1.9 8.9 7.4 0.74 10.2 1.9 3.0 2 0 0 2 2 2 0 Csm1 N-terminal domain Ank_2 PF12796.7 KFP21524.1 - 3.6e-37 126.8 4.9 3.3e-12 46.8 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP21524.1 - 1.2e-36 124.3 8.6 1.2e-07 31.9 0.2 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP21524.1 - 3e-32 110.6 4.4 3.1e-08 34.0 0.1 4.8 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP21524.1 - 6.2e-31 105.5 8.4 8.6e-05 22.8 0.1 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KFP21524.1 - 2.2e-30 101.3 2.1 5.3e-05 23.3 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat SAM_1 PF00536.30 KFP21524.1 - 5.5e-26 90.8 0.0 3e-15 56.4 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP21524.1 - 3.2e-22 78.4 0.3 1e-14 54.3 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PID PF00640.23 KFP21525.1 - 9.3e-21 74.3 0.4 1.4e-20 73.8 0.4 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP21525.1 - 7.6e-06 26.1 0.1 1.1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.6 KFP21525.1 - 4.2e-05 23.5 0.0 5.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.13 KFP21525.1 - 8.2e-05 22.0 0.1 0.00035 20.0 0.1 1.8 1 1 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 WD40 PF00400.32 KFP21526.1 - 1.4e-64 212.5 37.9 5e-09 36.6 0.0 13.3 13 0 0 13 13 13 10 WD domain, G-beta repeat NB-ARC PF00931.22 KFP21526.1 - 2.4e-57 194.0 1.4 2.6e-57 193.9 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain APAF1_C PF17908.1 KFP21526.1 - 3.6e-54 182.4 2.0 9.4e-54 181.1 2.0 1.8 1 0 0 1 1 1 1 APAF-1 helical domain ANAPC4_WD40 PF12894.7 KFP21526.1 - 5e-30 103.6 10.1 4.7e-05 23.6 0.1 9.8 2 2 7 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain CARD PF00619.21 KFP21526.1 - 1.6e-17 63.3 1.4 5e-17 61.7 1.4 2.0 1 0 0 1 1 1 1 Caspase recruitment domain Ge1_WD40 PF16529.5 KFP21526.1 - 3.2e-12 46.0 9.4 0.0015 17.5 2.9 7.7 3 3 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFP21526.1 - 5.5e-12 46.0 3.9 9.4e-05 22.4 0.0 5.3 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A CARD_2 PF16739.5 KFP21526.1 - 5.7e-10 39.0 0.4 1.7e-09 37.5 0.4 1.8 1 0 0 1 1 1 1 Caspase recruitment domain WD40_like PF17005.5 KFP21526.1 - 5.4e-08 32.5 2.9 0.64 9.3 0.0 5.8 4 2 2 6 6 6 3 WD40-like domain Nup160 PF11715.8 KFP21526.1 - 0.00014 20.7 8.8 0.036 12.7 0.0 5.3 4 2 2 6 6 6 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KFP21526.1 - 0.00043 20.3 0.1 2.2 8.4 0.0 5.6 3 2 4 7 7 7 1 Ciliary BBSome complex subunit 2, middle region AAA_16 PF13191.6 KFP21526.1 - 0.00046 20.6 0.0 0.00096 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFP21526.1 - 0.019 15.2 0.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2415 PF10313.9 KFP21526.1 - 0.023 14.6 0.0 0.3 11.1 0.0 3.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Viral_helicase1 PF01443.18 KFP21526.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2856 PF11043.8 KFP21526.1 - 0.2 11.8 0.6 8.3 6.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) PD40 PF07676.12 KFP21526.1 - 0.47 10.5 5.3 32 4.6 0.1 4.6 6 0 0 6 6 4 0 WD40-like Beta Propeller Repeat Snapin_Pallidin PF14712.6 KFP21527.1 - 0.0013 19.1 17.9 0.063 13.7 1.3 5.0 4 2 1 5 5 5 1 Snapin/Pallidin DUF148 PF02520.17 KFP21527.1 - 0.0091 16.1 4.3 0.0091 16.1 4.3 3.4 2 1 1 3 3 3 2 Domain of unknown function DUF148 Sec8_exocyst PF04048.14 KFP21527.1 - 0.024 14.6 0.9 0.024 14.6 0.9 2.9 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 KFP21527.1 - 0.062 13.5 13.3 1.7 8.8 2.0 3.6 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Cytochrom_B562 PF07361.11 KFP21527.1 - 0.38 11.4 9.9 0.52 11.0 0.4 3.6 2 1 1 4 4 4 0 Cytochrome b562 Spc7 PF08317.11 KFP21527.1 - 0.54 9.1 22.6 0.074 11.9 1.4 3.6 1 1 3 4 4 4 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KFP21527.1 - 0.9 10.0 20.5 1.3 9.5 4.8 4.5 2 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Rab5-bind PF09311.11 KFP21527.1 - 1.6 8.0 21.0 0.1 12.0 8.6 2.9 1 1 1 2 2 2 0 Rabaptin-like protein MutS_III PF05192.18 KFP21527.1 - 2.5 8.3 14.1 0.081 13.1 4.8 2.5 2 1 1 3 3 3 0 MutS domain III Lectin_N PF03954.14 KFP21527.1 - 3.7 7.3 18.7 0.19 11.5 2.2 3.8 2 2 0 3 3 3 0 Hepatic lectin, N-terminal domain Sec34 PF04136.15 KFP21527.1 - 7 6.5 22.8 9 6.2 0.3 4.9 2 2 3 5 5 5 0 Sec34-like family DUF948 PF06103.11 KFP21527.1 - 9.6 6.5 16.4 28 5.1 4.2 4.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.27 KFP21528.1 - 1.7e-46 156.0 9.0 2e-19 69.3 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein LEM PF03020.15 KFP21529.1 - 1.3e-19 69.5 0.3 3.1e-19 68.3 0.3 1.7 1 0 0 1 1 1 1 LEM domain Orf78 PF06024.12 KFP21529.1 - 0.057 13.7 0.1 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DotU PF09850.9 KFP21529.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system protein DotU PBP1_TM PF14812.6 KFP21529.1 - 0.8 10.1 8.4 0.92 9.9 0.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_2 PF07719.17 KFP21531.1 - 0.042 14.0 2.1 1.4 9.2 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFP21531.1 - 0.06 13.6 2.0 13 6.1 0.1 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP21531.1 - 0.12 12.6 0.2 17 5.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Dynein_heavy PF03028.15 KFP21531.1 - 0.13 12.3 0.6 0.86 9.7 0.2 2.5 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain DUF4486 PF14858.6 KFP21532.1 - 2.2e-273 907.7 3.9 2.6e-273 907.5 3.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Pkinase PF00069.25 KFP21533.1 - 1.5e-72 244.2 0.0 2.8e-72 243.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21533.1 - 5.3e-35 120.9 0.0 1.1e-34 119.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFP21533.1 - 5e-07 29.0 0.1 2.4e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP21533.1 - 2.9e-06 26.8 0.0 6.6e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP21533.1 - 0.00028 20.3 0.3 0.00072 19.0 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFP21533.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KFP21533.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFP21533.1 - 0.12 11.1 0.2 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Ets PF00178.22 KFP21534.1 - 1.8e-34 118.1 3.0 3.2e-34 117.2 3.0 1.4 1 0 0 1 1 1 1 Ets-domain Translat_reg PF01818.17 KFP21534.1 - 0.041 13.9 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage translational regulator DUF3399 PF11879.8 KFP21534.1 - 7.5 6.9 10.4 0.32 11.4 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) Peptidase_M1 PF01433.20 KFP21535.1 - 4.6e-46 157.1 0.0 6.8e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFP21535.1 - 1.5e-36 124.9 0.0 2.6e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFP21535.1 - 1.2e-18 68.0 0.0 1.9e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 KFP21535.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Lyase_aromatic PF00221.19 KFP21536.1 - 8.2e-195 647.9 0.1 9.6e-195 647.6 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 KFP21536.1 - 1.1e-05 25.5 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Amidohydro_3 PF07969.11 KFP21537.1 - 9.5e-25 88.0 0.9 5.5e-17 62.4 0.0 2.8 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFP21537.1 - 7.3e-23 81.4 3.1 6e-22 78.4 3.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family LSM PF01423.22 KFP21538.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Laminin_N PF00055.17 KFP21539.1 - 8.7e-37 126.9 0.0 8.7e-37 126.9 0.0 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KFP21539.1 - 6.8e-30 103.0 49.4 1.3e-12 47.7 5.8 5.3 3 1 1 4 4 4 3 Laminin EGF domain NTR PF01759.21 KFP21539.1 - 1.9e-22 79.1 0.2 3.6e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 UNC-6/NTR/C345C module UCH PF00443.29 KFP21540.1 - 1.4e-55 188.6 0.0 3.8e-55 187.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP21540.1 - 1.5e-20 73.3 8.7 1.5e-20 73.3 8.7 2.8 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFP21540.1 - 1.1e-14 54.7 4.2 1.1e-14 54.7 4.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Relaxase PF03432.14 KFP21540.1 - 0.16 11.5 2.1 0.35 10.4 2.1 1.5 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain MPM1 PF17234.2 KFP21540.1 - 0.27 11.5 8.5 0.031 14.6 4.1 1.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 zf-UBP_var PF17807.1 KFP21540.1 - 1.6 8.6 4.9 0.33 10.7 0.6 2.0 2 0 0 2 2 2 0 Variant UBP zinc finger Peptidase_M24 PF00557.24 KFP21541.1 - 2.4e-46 158.1 0.0 3.1e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 KFP21541.1 - 0.15 12.5 0.0 0.57 10.7 0.0 1.9 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Vezatin PF12632.7 KFP21542.1 - 3.1e-93 312.2 0.9 3.1e-93 312.2 0.9 2.2 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes YwiC PF14256.6 KFP21542.1 - 0.21 11.9 2.9 0.36 11.1 2.9 1.3 1 0 0 1 1 1 0 YwiC-like protein DUF4131 PF13567.6 KFP21542.1 - 0.31 10.7 2.2 0.65 9.6 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF641 PF04859.12 KFP21542.1 - 1.3 9.3 8.5 0.26 11.6 1.3 2.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) RhoGEF PF00621.20 KFP21543.1 - 3.9e-37 128.2 2.2 1.3e-36 126.5 2.2 2.0 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KFP21543.1 - 3.3e-20 72.0 10.2 7.7e-20 70.8 10.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KFP21543.1 - 8.7e-18 64.8 2.0 2e-08 34.7 0.0 3.1 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 KFP21543.1 - 1.1e-05 25.3 3.4 0.00074 19.4 2.3 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFP21543.1 - 3.3e-05 23.9 1.0 8.7e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 KFP21543.1 - 0.0022 18.2 8.2 0.0022 18.2 8.2 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger PH_11 PF15413.6 KFP21543.1 - 0.0022 18.4 3.9 0.12 12.8 0.1 3.9 4 0 0 4 4 4 1 Pleckstrin homology domain PH_9 PF15410.6 KFP21543.1 - 0.56 10.6 2.2 7.8 6.9 0.8 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain zf-SNAP50_C PF12251.8 KFP21543.1 - 1.7 8.3 8.8 3.1 7.4 7.9 1.9 1 1 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-C4 PF00105.18 KFP21544.1 - 2e-31 108.3 15.6 4.5e-31 107.1 15.6 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP21544.1 - 1.7e-29 102.9 0.5 4.2e-29 101.6 0.1 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor DUF2318 PF10080.9 KFP21544.1 - 6.8 6.9 10.3 0.087 12.9 0.6 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) NDUFA12 PF05071.16 KFP21545.1 - 5.5e-30 104.1 3.7 6.5e-30 103.8 3.7 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Tmemb_cc2 PF10267.9 KFP21546.1 - 5.7e-162 539.4 13.2 6.5e-162 539.3 13.2 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.6 KFP21546.1 - 0.0044 17.1 0.2 0.0044 17.1 0.2 3.5 2 1 1 3 3 2 1 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.6 KFP21546.1 - 0.013 15.7 0.1 0.013 15.7 0.1 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain VPS11_C PF12451.8 KFP21546.1 - 0.14 12.4 0.5 0.14 12.4 0.5 3.7 6 0 0 6 6 3 0 Vacuolar protein sorting protein 11 C terminal Exonuc_VII_L PF02601.15 KFP21546.1 - 0.17 11.4 18.2 1.1 8.8 8.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4735 PF15882.5 KFP21546.1 - 0.39 10.1 12.0 0.21 11.0 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4735) DDHD PF02862.17 KFP21546.1 - 0.56 10.3 5.5 11 6.1 0.1 2.2 2 0 0 2 2 2 0 DDHD domain COG2 PF06148.11 KFP21546.1 - 0.61 10.2 16.5 0.093 12.8 4.2 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.8 KFP21546.1 - 2 5.8 31.3 0.35 8.3 13.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Lipoprotein_20 PF13942.6 KFP21546.1 - 2.1 8.2 17.9 0.31 10.9 4.1 2.4 2 1 0 2 2 2 0 YfhG lipoprotein DUF4483 PF14825.6 KFP21546.1 - 2.2 8.0 10.0 0.027 14.2 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) Phage_GPO PF05929.11 KFP21546.1 - 3.1 7.4 22.0 0.028 14.1 2.6 3.3 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase MbeB_N PF04837.12 KFP21546.1 - 3.1 8.2 9.5 2.6 8.4 0.8 3.2 2 0 0 2 2 2 0 MbeB-like, N-term conserved region CorA PF01544.18 KFP21546.1 - 4.4 6.5 14.1 4 6.7 0.8 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CARD PF00619.21 KFP21547.1 - 5.3e-16 58.4 0.1 8.8e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.22 KFP21547.1 - 1.3e-13 50.9 0.3 2.3e-12 46.9 0.1 2.2 2 0 0 2 2 2 1 Death domain CARD_2 PF16739.5 KFP21547.1 - 0.00081 19.3 0.2 0.0022 17.9 0.1 1.8 2 0 0 2 2 2 1 Caspase recruitment domain SH2 PF00017.24 KFP21548.1 - 1.4e-13 50.7 0.1 2.1e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KFP21548.1 - 1.1e-11 44.9 1.8 1.2e-11 44.7 0.7 1.6 2 0 0 2 2 2 1 SOCS box SH2_2 PF14633.6 KFP21548.1 - 0.00094 18.6 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Condensation PF00668.20 KFP21548.1 - 0.016 13.9 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Condensation domain MRP-S32 PF10210.9 KFP21549.1 - 2.4e-37 127.3 1.8 3.2e-37 127.0 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 NUDIX PF00293.28 KFP21550.1 - 2.8e-16 59.7 0.4 3.3e-16 59.5 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain FYVE PF01363.21 KFP21551.1 - 3e-20 72.1 10.7 3e-20 72.1 10.7 2.3 2 0 0 2 2 2 1 FYVE zinc finger CENP-F_leu_zip PF10473.9 KFP21551.1 - 0.00092 19.2 21.7 0.00092 19.2 21.7 14.8 3 3 10 15 15 15 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IBR PF01485.21 KFP21551.1 - 0.014 15.6 5.3 0.076 13.3 5.3 2.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Filament PF00038.21 KFP21551.1 - 0.19 11.3 284.4 0.016 14.8 62.3 10.1 1 1 7 8 8 8 0 Intermediate filament protein zf-RING_2 PF13639.6 KFP21551.1 - 2.2 8.7 11.7 4.3 7.8 9.6 2.4 2 0 0 2 2 2 0 Ring finger domain RhoGEF PF00621.20 KFP21552.1 - 6.3e-20 72.2 4.3 1e-19 71.5 3.8 1.7 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 KFP21552.1 - 8.1e-09 35.5 1.4 5.1e-05 23.1 0.2 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH_16 PF17838.1 KFP21552.1 - 7.1e-06 25.9 0.9 0.029 14.2 0.1 2.8 3 0 0 3 3 3 2 PH domain PH_5 PF15405.6 KFP21552.1 - 0.0016 18.6 4.5 0.002 18.2 0.4 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Phage_int_SAM_1 PF02899.17 KFP21552.1 - 0.0098 16.2 0.2 1.6 9.1 0.0 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain PH PF00169.29 KFP21552.1 - 0.014 15.8 3.1 0.02 15.4 0.4 2.6 2 2 0 2 2 2 0 PH domain BTG PF07742.12 KFP21553.1 - 7.1e-31 106.5 0.0 9e-31 106.1 0.0 1.1 1 0 0 1 1 1 1 BTG family CitMHS PF03600.16 KFP21554.1 - 1.3e-56 192.0 19.3 1.3e-56 192.0 19.3 1.9 2 1 1 3 3 3 2 Citrate transporter ArsB PF02040.15 KFP21554.1 - 2.8e-09 36.8 22.5 9.7e-05 21.9 4.0 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein RAMP4 PF06624.12 KFP21554.1 - 4.1 7.5 4.9 18 5.5 4.0 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 RCC1 PF00415.18 KFP21555.1 - 3.1e-231 748.1 86.3 2.7e-15 56.7 0.1 21.4 21 0 0 21 21 21 19 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP21555.1 - 5.3e-89 290.6 109.4 9.2e-08 31.7 0.3 21.9 22 0 0 22 22 22 16 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 KFP21555.1 - 8.2e-59 199.6 0.0 1.6e-58 198.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.8 KFP21555.1 - 6.2e-35 119.3 2.4 8.4e-35 118.9 0.8 2.1 2 0 0 2 2 2 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.13 KFP21555.1 - 5.5e-22 77.8 5.0 5.5e-22 77.8 5.0 5.7 7 0 0 7 7 7 1 Mib_herc2 Cyt-b5 PF00173.28 KFP21555.1 - 2.8e-10 40.2 0.0 1e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.17 KFP21555.1 - 9.1e-10 38.2 7.0 2.2e-09 37.0 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type SH3_15 PF18346.1 KFP21555.1 - 3e-06 27.4 5.0 0.00014 22.1 0.6 3.7 3 0 0 3 3 3 1 Mind bomb SH3 repeat domain ANAPC10 PF03256.16 KFP21555.1 - 4e-06 26.6 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Hira PF07569.11 KFP21555.1 - 0.061 13.0 0.7 67 3.1 0.0 5.4 6 0 0 6 6 6 0 TUP1-like enhancer of split Ubie_methyltran PF01209.18 KFP21555.1 - 0.1 11.9 0.7 20 4.4 0.0 3.7 4 0 0 4 4 4 0 ubiE/COQ5 methyltransferase family zf-UBR PF02207.20 KFP21555.1 - 0.46 10.7 5.3 0.22 11.7 2.2 2.1 2 0 0 2 2 1 0 Putative zinc finger in N-recognin (UBR box) Med3 PF11593.8 KFP21555.1 - 1.3 8.2 5.4 0.17 11.0 1.0 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Mg_trans_NIPA PF05653.14 KFP21556.1 - 2.2e-70 237.1 14.9 2.5e-70 236.9 14.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFP21556.1 - 0.0042 17.3 4.5 0.0042 17.3 4.5 3.2 2 1 1 3 3 3 2 EamA-like transporter family DUF3611 PF12263.8 KFP21556.1 - 0.048 13.5 0.2 0.048 13.5 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) Acyl_transf_3 PF01757.22 KFP21556.1 - 0.51 9.4 14.1 0.61 9.1 10.8 2.1 1 1 1 2 2 2 0 Acyltransferase family DUF2973 PF11189.8 KFP21556.1 - 1.4 9.0 3.3 0.49 10.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) G-alpha PF00503.20 KFP21560.1 - 4.5e-122 407.6 3.3 5.2e-122 407.4 3.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP21560.1 - 2.4e-17 63.0 0.7 1e-09 38.1 0.1 3.4 2 1 0 3 3 3 3 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP21560.1 - 0.00025 20.5 2.2 0.067 12.5 0.6 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFP21560.1 - 0.00085 19.5 1.0 1.4 9.2 0.1 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP21560.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 KFP21560.1 - 0.081 12.5 2.4 5.6 6.5 0.4 3.0 2 1 1 3 3 3 0 Ras family AAA_29 PF13555.6 KFP21560.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KFP21560.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KFP21560.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFP21561.1 - 2.2e-120 402.1 2.5 2.8e-120 401.7 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP21561.1 - 1.2e-15 57.4 1.0 1.5e-11 44.0 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KFP21561.1 - 0.0015 18.8 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFP21561.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Gtr1_RagA PF04670.12 KFP21561.1 - 0.0064 15.9 3.1 0.38 10.1 0.5 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KFP21561.1 - 0.072 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KFP21561.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 KFP21561.1 - 0.14 11.3 0.2 0.24 10.5 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CD36 PF01130.21 KFP21562.1 - 1e-143 479.3 0.0 1.2e-143 479.1 0.0 1.0 1 0 0 1 1 1 1 CD36 family Sema PF01403.19 KFP21563.1 - 3.7e-148 493.8 0.0 5.4e-148 493.3 0.0 1.2 1 0 0 1 1 1 1 Sema domain I-set PF07679.16 KFP21563.1 - 8e-06 25.8 0.2 2.3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21563.1 - 1.4e-05 25.6 0.1 7.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain PSI PF01437.25 KFP21563.1 - 0.00085 19.8 7.5 0.0026 18.3 7.5 1.9 1 0 0 1 1 1 1 Plexin repeat Ig_2 PF13895.6 KFP21563.1 - 0.007 16.7 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP21563.1 - 0.0094 16.1 0.1 0.26 11.5 0.1 3.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KFP21563.1 - 0.014 15.5 1.0 0.037 14.2 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain SPT16 PF08644.11 KFP21563.1 - 0.13 12.4 0.3 0.33 11.1 0.3 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Kringle PF00051.18 KFP21567.1 - 1.8e-111 364.6 41.2 1.3e-29 102.3 7.0 4.5 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.26 KFP21567.1 - 6.3e-48 163.5 0.0 1.2e-47 162.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.26 KFP21567.1 - 4.3e-10 39.4 1.2 1.3e-09 37.9 1.2 1.9 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.11 KFP21567.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) VGCC_alpha2 PF08473.11 KFP21568.1 - 4e-208 691.5 1.4 6.6e-208 690.8 1.4 1.3 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 KFP21568.1 - 2e-40 138.1 0.2 5e-40 136.8 0.2 1.7 1 0 0 1 1 1 1 VWA N-terminal VWA PF00092.28 KFP21568.1 - 4e-22 79.3 0.4 7.1e-22 78.5 0.4 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFP21568.1 - 5.7e-14 52.3 0.0 9.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFP21568.1 - 7.4e-11 42.7 0.2 1.9e-10 41.3 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KFP21568.1 - 2.6e-10 40.5 7.4 1.1e-09 38.5 0.1 3.5 3 1 0 3 3 3 1 Cache domain vWA-TerF-like PF10138.9 KFP21568.1 - 0.0033 17.6 0.4 0.0065 16.6 0.4 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus PsbP PF01789.16 KFP21569.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 PsbP C2 PF00168.30 KFP21572.1 - 5.9e-39 132.5 0.3 1.2e-24 86.6 0.0 2.9 2 0 0 2 2 2 2 C2 domain PDZ PF00595.24 KFP21572.1 - 9e-06 26.0 0.4 2.3e-05 24.6 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP21572.1 - 5.4e-05 23.0 0.0 0.00019 21.2 0.0 2.0 1 0 0 1 1 1 1 PDZ domain GPS2_interact PF15784.5 KFP21572.1 - 1.7 9.1 17.9 0.022 15.2 1.3 3.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Sema PF01403.19 KFP21575.1 - 2.7e-149 497.6 0.0 3.6e-149 497.2 0.0 1.2 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFP21575.1 - 3.5e-05 23.9 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP21575.1 - 0.00067 19.8 0.9 0.0022 18.1 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain PSI PF01437.25 KFP21575.1 - 0.0065 17.0 6.3 0.0065 17.0 6.3 2.0 2 0 0 2 2 2 1 Plexin repeat Sema PF01403.19 KFP21577.1 - 1.5e-160 534.6 0.0 2.1e-160 534.2 0.0 1.2 1 0 0 1 1 1 1 Sema domain ig PF00047.25 KFP21577.1 - 1e-07 32.0 0.0 2.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP21577.1 - 2.2e-05 24.6 0.1 0.0001 22.5 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP21577.1 - 0.0011 19.6 0.0 0.0039 17.8 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 KFP21577.1 - 0.0025 18.3 6.9 0.0025 18.3 6.9 2.0 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.6 KFP21577.1 - 0.0028 18.0 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP21577.1 - 0.02 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_6 PF18452.1 KFP21577.1 - 0.042 13.4 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Sema PF01403.19 KFP21579.1 - 2.6e-164 547.0 0.0 9.7e-163 541.9 0.0 2.1 1 1 1 2 2 2 2 Sema domain V-set PF07686.17 KFP21579.1 - 0.00097 19.3 0.1 0.066 13.4 0.1 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KFP21579.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21579.1 - 0.0011 19.6 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP21579.1 - 0.0012 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.25 KFP21579.1 - 0.0012 19.3 8.8 0.0028 18.2 8.8 1.6 1 0 0 1 1 1 1 Plexin repeat Ig_6 PF18452.1 KFP21579.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP21579.1 - 0.007 16.7 0.1 0.053 13.9 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin domain RVT_1 PF00078.27 KFP21581.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANF_receptor PF01094.28 KFP21586.1 - 2.1e-104 349.4 0.1 2.7e-104 349.1 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KFP21586.1 - 2.1e-66 224.1 23.6 3.7e-66 223.2 23.6 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KFP21586.1 - 2.1e-13 50.0 12.4 5.7e-13 48.6 12.4 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 KFP21586.1 - 2e-09 37.6 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DDE_Tnp_IS1 PF03400.13 KFP21586.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase Ephrin_rec_like PF07699.13 KFP21587.1 - 5.3e-10 38.9 82.2 0.00024 20.8 7.2 8.9 5 3 3 8 8 8 7 Putative ephrin-receptor like NCD3G PF07562.14 KFP21587.1 - 0.17 11.9 69.0 0.11 12.5 8.4 7.8 7 1 0 7 7 7 0 Nine Cysteines Domain of family 3 GPCR Myb_DNA-binding PF00249.31 KFP21588.1 - 1.4e-31 108.4 13.7 8.2e-20 70.7 0.7 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFP21588.1 - 4.3e-15 55.7 5.6 1.4e-08 34.9 0.1 4.4 2 1 2 4 4 4 2 Myb-like DNA-binding domain DUF5591 PF17884.1 KFP21588.1 - 0.0073 16.2 0.4 4 7.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5591) DUF3818 PF12825.7 KFP21588.1 - 0.016 14.3 1.6 0.032 13.3 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Myb_DNA-bind_4 PF13837.6 KFP21588.1 - 1.4 9.4 8.8 0.13 12.6 0.4 3.4 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF2678 PF10856.8 KFP21589.1 - 1.4e-50 170.1 5.7 1.6e-50 170.0 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Polysacc_synt_C PF14667.6 KFP21589.1 - 2.6e-06 27.5 2.0 3e-06 27.3 2.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF2417 PF10329.9 KFP21589.1 - 0.013 14.9 7.8 0.028 13.8 7.8 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) COPI_assoc PF08507.10 KFP21589.1 - 0.85 9.7 12.4 0.046 13.8 3.9 2.0 1 1 0 2 2 2 0 COPI associated protein 7TMR-DISM_7TM PF07695.11 KFP21589.1 - 1.3 8.9 11.9 8.1 6.3 12.1 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling Meiosis_expr PF15163.6 KFP21590.1 - 4.4e-38 129.8 8.0 5.1e-38 129.6 8.0 1.1 1 0 0 1 1 1 1 Meiosis-expressed SET PF00856.28 KFP21591.1 - 7.1e-22 78.6 0.2 2.3e-21 76.9 0.1 1.9 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KFP21591.1 - 2.4e-17 63.6 7.3 5.9e-17 62.3 3.9 2.7 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 KFP21591.1 - 1.4e-14 53.7 1.5 2.9e-14 52.7 1.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AWS PF17907.1 KFP21591.1 - 0.0079 16.2 1.6 0.0079 16.2 1.6 3.4 3 0 0 3 3 3 1 AWS domain Cadherin PF00028.17 KFP21594.1 - 2.8e-81 268.1 2.7 2.3e-19 69.6 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP21594.1 - 8.2e-57 191.6 0.4 1.6e-56 190.7 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP21594.1 - 1e-05 25.3 0.0 0.16 11.8 0.0 3.5 4 0 0 4 4 4 2 Cadherin-like Invasin_D3 PF09134.10 KFP21594.1 - 8.1e-05 22.9 1.7 2.1 8.7 0.1 3.7 3 0 0 3 3 3 2 Invasin, domain 3 Cadherin_3 PF16184.5 KFP21594.1 - 0.00013 22.0 3.2 21 5.1 0.0 5.4 6 0 0 6 6 6 1 Cadherin-like Stevor PF17410.2 KFP21594.1 - 0.023 14.2 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ASFV_J13L PF05568.11 KFP21594.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Big_9 PF17963.1 KFP21594.1 - 0.46 11.3 5.0 16 6.3 0.5 3.8 3 0 0 3 3 3 0 Bacterial Ig domain RVT_1 PF00078.27 KFP21596.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFP21597.1 - 1.4e-68 227.3 3.5 5.6e-20 71.6 0.1 4.4 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 KFP21597.1 - 2e-05 24.6 6.6 0.016 15.2 0.1 4.5 5 0 0 5 5 5 1 Cadherin-like Cadherin_2 PF08266.12 KFP21597.1 - 7e-05 22.6 0.0 1 9.2 0.0 4.5 4 1 0 4 4 4 1 Cadherin-like Invasin_D3 PF09134.10 KFP21597.1 - 0.001 19.3 1.0 5.4 7.4 0.1 3.9 4 0 0 4 4 4 1 Invasin, domain 3 Cadherin_4 PF17803.1 KFP21597.1 - 0.011 16.4 8.3 2.6 8.7 2.7 3.7 3 0 0 3 3 3 0 Bacterial cadherin-like domain Cadherin_pro PF08758.11 KFP21597.1 - 0.066 13.4 0.0 4.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Cadherin prodomain like Big_9 PF17963.1 KFP21597.1 - 3.8 8.3 9.7 34 5.3 2.7 3.8 4 1 0 4 4 4 0 Bacterial Ig domain NTP_transferase PF00483.23 KFP21598.1 - 3.1e-14 53.2 0.0 4.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFP21598.1 - 2.1e-09 36.7 11.1 5e-07 29.2 2.0 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KFP21598.1 - 0.0022 16.2 0.1 0.0032 15.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KFP21598.1 - 0.011 15.5 0.4 0.095 12.5 0.5 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase I-set PF07679.16 KFP21599.1 - 1.4e-19 70.0 0.0 1.6e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21599.1 - 3.5e-13 50.0 0.0 4.9e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP21599.1 - 1.2e-08 35.0 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP21599.1 - 2.1e-07 31.1 0.0 5e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP21599.1 - 6.1e-07 29.7 0.0 7.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFP21599.1 - 0.00051 19.6 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP21599.1 - 0.00071 19.6 0.0 0.00083 19.3 0.0 1.1 1 0 0 1 1 1 1 C17orf99 Ig domain Filament PF00038.21 KFP21600.1 - 2.4e-115 385.4 47.2 2.7e-115 385.2 47.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.14 KFP21600.1 - 2.3e-06 28.4 0.9 3.8e-06 27.7 0.3 1.7 2 0 0 2 2 1 1 Intermediate filament head (DNA binding) region Golgin_A5 PF09787.9 KFP21600.1 - 0.0035 16.9 37.2 0.074 12.5 21.1 2.4 1 1 1 2 2 2 2 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KFP21600.1 - 0.0058 16.9 40.8 0.07 13.3 15.8 4.0 1 1 1 3 3 3 2 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 KFP21600.1 - 0.0067 16.5 1.4 0.0067 16.5 1.4 6.3 3 1 2 6 6 5 1 TolA binding protein trimerisation Trimer_CC PF08954.11 KFP21600.1 - 0.014 14.9 0.2 0.014 14.9 0.2 4.2 3 1 0 3 3 2 0 Trimerisation motif APG6_N PF17675.1 KFP21600.1 - 0.033 14.7 2.2 0.033 14.7 2.2 4.7 1 1 3 4 4 4 0 Apg6 coiled-coil region FAM184 PF15665.5 KFP21600.1 - 0.05 13.4 42.5 0.51 10.1 8.9 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 KFP21600.1 - 0.073 11.9 41.1 0.051 12.5 7.7 3.2 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3584 PF12128.8 KFP21600.1 - 0.074 10.6 38.0 1.7 6.0 37.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 KFP21600.1 - 0.074 12.4 43.6 0.54 9.6 1.2 4.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Patched PF02460.18 KFP21600.1 - 0.097 10.7 4.5 0.13 10.3 4.5 1.1 1 0 0 1 1 1 0 Patched family Baculo_PEP_C PF04513.12 KFP21600.1 - 0.18 11.9 16.5 2.1 8.4 0.2 4.4 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus KLRAQ PF10205.9 KFP21600.1 - 0.25 11.6 26.8 0.12 12.6 11.1 4.1 2 2 1 3 3 3 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 KFP21600.1 - 0.44 10.6 21.9 0.57 10.2 3.3 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) LURAP PF14854.6 KFP21600.1 - 0.55 10.2 5.7 1.2 9.1 0.3 3.4 2 1 1 3 3 3 0 Leucine rich adaptor protein TPR_MLP1_2 PF07926.12 KFP21600.1 - 0.72 9.9 43.4 2.6 8.1 8.5 4.4 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein WD40_alt PF14077.6 KFP21600.1 - 0.9 9.5 10.1 25 4.8 1.3 4.7 4 0 0 4 4 4 0 Alternative WD40 repeat motif TACC_C PF05010.14 KFP21600.1 - 1.4 8.7 37.1 0.29 10.9 7.4 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4515 PF14988.6 KFP21600.1 - 1.7 8.5 41.4 0.03 14.2 7.8 3.2 1 1 2 3 3 2 0 Domain of unknown function (DUF4515) DUF948 PF06103.11 KFP21600.1 - 1.7 9.0 10.5 23 5.4 0.0 4.4 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 KFP21600.1 - 1.9 8.8 14.8 8.9 6.6 4.7 4.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG KASH_CCD PF14662.6 KFP21600.1 - 2.5 7.9 41.0 7.9 6.3 16.0 3.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF573 PF04504.14 KFP21600.1 - 3.2 8.5 9.6 3.6 8.3 0.5 4.0 2 2 1 3 3 3 0 Protein of unknown function, DUF573 CENP-H PF05837.12 KFP21600.1 - 4 7.9 33.6 0.35 11.3 2.9 4.3 1 1 4 5 5 5 0 Centromere protein H (CENP-H) T6PP_N PF18572.1 KFP21600.1 - 4.7 7.1 15.3 0.28 11.0 7.3 3.1 2 2 1 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Fib_alpha PF08702.10 KFP21600.1 - 5.5 7.2 29.6 0.37 11.0 6.7 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Peptidase_M18 PF02127.15 KFP21601.1 - 4.5e-166 552.9 0.0 5.4e-166 552.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KFP21601.1 - 1.6e-07 30.7 0.0 1.3e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Y_phosphatase PF00102.27 KFP21602.1 - 2.2e-74 250.0 0.0 2.8e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP21602.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP21602.1 - 0.017 15.3 0.2 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFP21602.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Tubulin PF00091.25 KFP21603.1 - 6.1e-67 225.6 0.0 7.9e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP21603.1 - 4.4e-35 120.6 0.0 1e-34 119.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP21603.1 - 0.00094 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Pkinase PF00069.25 KFP21606.1 - 1.6e-42 145.7 0.0 1.9e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21606.1 - 1.4e-25 90.1 0.0 1.7e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP21606.1 - 0.0004 20.4 0.4 0.092 12.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP21606.1 - 0.0016 17.8 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFP21606.1 - 0.0023 17.3 0.1 0.0031 16.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_35 PF01301.19 KFP21607.1 - 4.9e-89 299.1 0.0 6e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFP21607.1 - 1.4e-09 38.5 0.0 7.9e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 KFP21607.1 - 2.1e-09 37.2 0.0 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase bVLRF1 PF18826.1 KFP21608.1 - 1.2e-52 177.8 0.0 2.4e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 KFP21608.1 - 1e-19 70.1 1.7 1e-19 70.1 1.7 2.3 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 KFP21608.1 - 1.7e-08 34.5 0.4 2.1e-07 31.1 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP21608.1 - 4.9e-07 30.2 0.0 1.9e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP21608.1 - 5.8e-06 26.5 0.1 1.6e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KFP21608.1 - 1.5e-05 25.0 0.1 8.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KFP21608.1 - 0.00015 22.3 0.0 0.0031 18.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-FCS PF06467.14 KFP21608.1 - 0.12 12.3 11.9 5 7.1 0.4 3.6 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif APG9 PF04109.16 KFP21609.1 - 6.7e-170 566.2 10.2 8.4e-170 565.9 10.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.24 KFP21609.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MTABC_N PF16185.5 KFP21610.1 - 3.9e-39 134.6 4.9 1e-38 133.3 4.9 1.7 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 KFP21610.1 - 1.3e-38 133.2 11.6 2.1e-38 132.6 11.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFP21610.1 - 6.3e-35 120.7 0.0 1.1e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFP21610.1 - 9.6e-07 28.5 0.1 0.0001 21.8 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFP21610.1 - 3.1e-05 24.4 0.1 7.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFP21610.1 - 0.0013 18.5 0.1 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFP21610.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFP21610.1 - 0.0018 18.5 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFP21610.1 - 0.0053 17.2 0.0 0.083 13.3 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KFP21610.1 - 0.0064 16.3 0.1 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KFP21610.1 - 0.014 15.6 0.3 0.3 11.3 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Acyl-CoA_dh_1 PF00441.24 KFP21610.1 - 0.021 15.0 0.1 0.075 13.2 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain AAA_24 PF13479.6 KFP21610.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFP21610.1 - 0.05 12.9 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KFP21610.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFP21610.1 - 0.077 13.0 0.2 0.57 10.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFP21610.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFP21610.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KFP21610.1 - 0.12 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KFP21610.1 - 0.13 12.0 0.1 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 KFP21610.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 KFP21610.1 - 0.18 11.4 0.0 0.49 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain zf-AN1 PF01428.16 KFP21611.1 - 4.6e-20 71.5 27.2 7.3e-12 45.2 12.1 2.9 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFP21611.1 - 0.039 14.3 16.4 0.5 10.8 2.9 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.6 KFP21611.1 - 0.11 12.5 10.6 0.27 11.2 1.6 3.4 3 0 0 3 3 3 0 zinc-ribbon domain UCH_1 PF13423.6 KFP21611.1 - 2.1 7.9 5.9 2.6 7.6 5.9 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase zinc-ribbons_6 PF07191.12 KFP21611.1 - 2.5 8.2 18.4 0.47 10.5 3.8 2.4 2 0 0 2 2 2 0 zinc-ribbons IBR PF01485.21 KFP21611.1 - 3.9 7.8 25.9 23 5.3 16.8 3.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Reticulon PF02453.17 KFP21612.1 - 0.12 12.3 0.4 0.24 11.3 0.4 1.4 1 0 0 1 1 1 0 Reticulon DUF4401 PF14351.6 KFP21612.1 - 0.19 11.0 3.0 1.2 8.3 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) Cyclin PF08613.11 KFP21613.1 - 2e-07 31.5 0.0 2.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFP21613.1 - 4.2e-06 26.5 0.0 6.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Xan_ur_permease PF00860.20 KFP21614.1 - 8.7e-68 228.8 18.5 4.3e-67 226.5 18.5 1.8 1 1 0 1 1 1 1 Permease family Bap31 PF05529.12 KFP21614.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region MFS_MOT1 PF16983.5 KFP21614.1 - 5.4 7.5 27.5 0.045 14.1 4.7 3.4 4 1 0 4 4 4 0 Molybdate transporter of MFS superfamily Homeodomain PF00046.29 KFP21615.1 - 1.7e-22 79.0 7.2 2.6e-22 78.4 7.2 1.3 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 KFP21615.1 - 0.00099 18.8 0.4 0.0015 18.2 0.4 1.3 1 0 0 1 1 1 1 QLQ Crystall PF00030.19 KFP21616.1 - 6.6e-39 132.0 4.4 1.3e-27 95.8 0.2 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin IL4_i_Ig PF18258.1 KFP21616.1 - 0.0028 17.8 0.9 1.7 8.9 0.1 3.0 2 1 1 3 3 3 2 Interleukin-4 inducing immunoglobulin-binding domain Ets PF00178.22 KFP21617.1 - 3.7e-37 126.7 0.4 4.1e-37 126.5 0.4 1.0 1 0 0 1 1 1 1 Ets-domain p450 PF00067.22 KFP21618.1 - 5.1e-99 332.1 0.0 6.1e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TTL PF03133.15 KFP21619.1 - 4.7e-101 337.8 0.1 7.2e-101 337.2 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFP21619.1 - 2.7e-06 26.8 0.1 0.00029 20.2 0.0 3.0 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFP21619.1 - 0.0013 18.1 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Pkinase PF00069.25 KFP21620.1 - 7.9e-78 261.5 0.0 1.5e-77 260.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21620.1 - 6.7e-43 146.8 0.0 1.1e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21620.1 - 0.00095 18.6 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP21620.1 - 0.0013 17.8 0.0 0.0031 16.5 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP21620.1 - 0.0054 15.6 0.0 0.0097 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP21620.1 - 0.0077 16.2 7.3 0.01 15.7 0.0 4.1 4 1 0 4 4 4 1 Phosphotransferase enzyme family Cohesin_HEAT PF12765.7 KFP21620.1 - 0.025 14.9 0.1 0.55 10.6 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RIO1 PF01163.22 KFP21620.1 - 0.16 11.5 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KFP21620.1 - 0.24 10.4 0.1 0.38 9.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RWD PF05773.22 KFP21621.1 - 2e-08 34.5 0.0 4.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_11 PF17123.5 KFP21621.1 - 5.5e-06 26.0 5.1 5.5e-06 26.0 5.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 KFP21621.1 - 1.7e-05 25.1 11.2 0.00016 21.9 11.2 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP21621.1 - 0.00072 19.5 11.8 0.0028 17.6 11.8 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP21621.1 - 0.0056 16.5 3.4 0.0056 16.5 3.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP21621.1 - 0.006 16.6 6.9 0.027 14.5 2.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFP21621.1 - 0.025 14.4 7.3 0.38 10.7 7.7 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP21621.1 - 0.15 12.1 5.7 0.35 11.0 1.9 2.4 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 KFP21621.1 - 2.6 8.2 7.5 1.8 8.8 3.9 1.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain Zf_RING PF16744.5 KFP21621.1 - 6.1 7.0 6.3 1.5 9.0 2.8 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger BCS1_N PF08740.11 KFP21622.1 - 9.9e-47 159.3 2.9 1.4e-46 158.9 2.9 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KFP21622.1 - 3.6e-20 72.7 0.0 5.8e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFP21622.1 - 0.00032 21.0 0.0 0.0029 18.0 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 KFP21622.1 - 0.0011 19.4 0.3 0.0049 17.3 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KFP21622.1 - 0.0039 16.4 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KFP21622.1 - 0.0082 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KFP21622.1 - 0.0088 16.0 0.0 0.028 14.3 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KFP21622.1 - 0.014 15.3 0.0 0.048 13.6 0.0 1.8 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFP21622.1 - 0.034 14.3 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.11 KFP21622.1 - 0.038 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_25 PF13481.6 KFP21622.1 - 0.041 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFP21622.1 - 0.046 13.5 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFP21622.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KFP21622.1 - 0.093 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP21622.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFP21622.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFP21622.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFP21622.1 - 0.16 12.3 0.0 0.97 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KFP21622.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KFP21622.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFP21622.1 - 0.23 11.6 0.0 0.74 9.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rcd1 PF04078.13 KFP21623.1 - 1.2e-134 447.6 0.8 1.3e-134 447.4 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like UCH PF00443.29 KFP21624.1 - 5e-55 186.8 11.4 9.1e-55 185.9 11.4 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_N PF16674.5 KFP21624.1 - 5.1e-44 148.5 0.0 1.1e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 UCH_1 PF13423.6 KFP21624.1 - 1.7e-11 44.3 21.2 9.6e-09 35.3 21.2 3.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 KFP21624.1 - 2.1e-08 33.5 20.7 0.00025 20.7 0.2 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Peptidase_C98 PF15499.6 KFP21624.1 - 0.033 13.7 7.2 0.16 11.4 4.0 3.1 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Phage_1_1 PF08200.11 KFP21624.1 - 0.48 10.9 3.0 1.1 9.7 0.6 2.8 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein Elongin_A PF06881.11 KFP21624.1 - 2.9 8.5 12.9 0.4 11.2 7.8 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Gelsolin PF00626.22 KFP21625.1 - 7.1e-67 221.3 0.1 3.6e-18 65.2 0.0 6.2 6 0 0 6 6 6 5 Gelsolin repeat VHP PF02209.19 KFP21625.1 - 1.4e-17 63.4 1.7 2.8e-17 62.5 1.7 1.6 1 0 0 1 1 1 1 Villin headpiece domain 7tm_4 PF13853.6 KFP21626.1 - 5.2e-47 160.9 14.8 6.1e-47 160.7 14.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP21626.1 - 9.4e-30 103.8 14.0 1.4e-29 103.3 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1240 PF06836.12 KFP21626.1 - 2.6 8.6 9.7 0.44 11.1 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) 7tm_4 PF13853.6 KFP21627.1 - 3.5e-42 145.0 16.6 4.2e-42 144.8 16.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP21627.1 - 3.3e-29 102.0 16.5 4.5e-29 101.6 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RabGAP-TBC PF00566.18 KFP21628.1 - 2e-53 181.3 5.0 3.1e-53 180.6 5.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SAYSvFN PF10260.9 KFP21628.1 - 0.39 10.7 1.7 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) LRR_6 PF13516.6 KFP21629.1 - 7.7e-36 119.1 38.6 8.2e-05 22.4 0.3 11.7 13 0 0 13 13 13 8 Leucine Rich repeat LRR_RI_capping PF18779.1 KFP21629.1 - 6.8e-18 64.0 3.0 6.8e-18 64.0 3.0 2.7 2 0 0 2 2 2 1 Capping Ribonuclease inhibitor Leucine Rich Repeat LRR_4 PF12799.7 KFP21629.1 - 4.4e-15 55.5 33.4 0.0021 18.4 0.1 8.9 4 1 7 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP21629.1 - 0.0056 16.4 25.9 2.6 7.9 0.8 7.7 5 1 3 8 8 8 5 Leucine rich repeat LRR_1 PF00560.33 KFP21629.1 - 0.018 15.5 39.0 4.1 8.3 0.1 11.3 14 0 0 14 14 14 0 Leucine Rich Repeat Choline_kinase PF01633.20 KFP21630.1 - 1.9e-71 240.0 0.1 2.8e-71 239.5 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFP21630.1 - 1.9e-07 31.3 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFP21630.1 - 1.6e-05 24.3 0.3 5.7e-05 22.6 0.3 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 KFP21630.1 - 0.036 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Helo_like_N PF17111.5 KFP21630.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Kdo PF06293.14 KFP21630.1 - 0.12 11.7 0.1 0.27 10.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.28 KFP21631.1 - 1.2e-11 45.3 0.1 1.2e-11 45.3 0.1 3.1 2 1 1 3 3 3 1 SET domain DUF3970 PF13113.6 KFP21631.1 - 0.083 13.1 0.1 0.29 11.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) PDEase_I PF00233.19 KFP21633.1 - 5.5e-72 242.3 0.3 1.4e-70 237.7 0.1 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KFP21633.1 - 2.1e-29 102.8 0.0 1.6e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KFP21633.1 - 6.3e-19 68.6 0.0 8.2e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KFP21633.1 - 5.4e-09 36.5 0.0 1.2e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 GAF domain SpoVT_C PF15714.5 KFP21633.1 - 1.4e-05 25.2 0.0 0.003 17.6 0.0 2.6 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor HD PF01966.22 KFP21633.1 - 0.018 15.3 0.3 0.12 12.6 0.2 2.2 2 0 0 2 2 2 0 HD domain H_kinase_N PF12282.8 KFP21633.1 - 0.071 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Signal transduction histidine kinase DUF4748 PF15932.5 KFP21633.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) RabGAP-TBC PF00566.18 KFP21634.1 - 1.5e-56 191.5 0.1 2e-56 191.1 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lamp PF01299.17 KFP21636.1 - 5.5e-61 204.8 11.7 1.1e-47 161.7 1.9 2.2 2 0 0 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFP21636.1 - 2e-08 34.2 2.5 1.4e-06 28.2 0.1 2.3 2 0 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) NFACT-R_1 PF05670.13 KFP21636.1 - 0.055 14.1 0.8 0.19 12.4 0.3 2.1 3 0 0 3 3 3 0 NFACT protein RNA binding domain Cullin PF00888.22 KFP21637.1 - 3.3e-208 693.3 19.7 5e-208 692.7 19.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFP21637.1 - 3.2e-24 84.7 0.3 1.3e-23 82.8 0.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KFP21637.1 - 0.0053 16.8 0.3 0.0053 16.8 0.3 3.2 2 1 0 3 3 3 1 SecA Wing and Scaffold domain OSCP PF00213.18 KFP21637.1 - 0.44 10.7 3.0 4.2 7.5 0.0 3.3 2 1 1 3 3 3 0 ATP synthase delta (OSCP) subunit PG_binding_4 PF12229.8 KFP21637.1 - 1.1 9.5 4.0 3.4 8.0 0.1 3.6 5 0 0 5 5 5 0 Putative peptidoglycan binding domain Trypsin PF00089.26 KFP21638.1 - 5.9e-65 219.2 0.0 6.6e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP21638.1 - 1.2e-05 26.2 0.0 2.2e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP21638.1 - 3e-05 24.4 0.0 5.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) RhoGEF PF00621.20 KFP21639.1 - 4e-39 134.7 5.6 4e-39 134.7 5.6 3.5 2 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 KFP21639.1 - 2.7e-09 37.5 0.1 6.8e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 KFP21639.1 - 5.6e-08 33.0 0.0 1.3e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFP21639.1 - 8.2e-08 32.7 13.9 4.2e-05 24.0 0.0 5.1 3 2 1 4 4 4 2 Spectrin repeat PH_10 PF15411.6 KFP21639.1 - 0.012 15.8 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain MCPsignal PF00015.21 KFP21639.1 - 0.48 10.2 2.1 2.3 8.0 0.0 2.9 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PhoLip_ATPase_C PF16212.5 KFP21640.1 - 5.6e-80 268.7 30.3 5.6e-80 268.7 30.3 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP21640.1 - 6.6e-22 77.0 0.3 6.6e-22 77.0 0.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP21640.1 - 3.8e-11 43.7 0.3 3.2e-05 24.3 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP21640.1 - 1.5e-10 41.0 0.1 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP21640.1 - 4.3e-10 39.4 1.2 1.2e-09 37.9 0.0 2.4 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP21640.1 - 0.00075 19.3 0.0 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFP21640.1 - 0.007 16.8 0.1 0.6 10.5 0.1 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GCP_C_terminal PF04130.13 KFP21641.1 - 5.3e-83 279.0 11.7 5.3e-83 279.0 11.7 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFP21641.1 - 1e-81 274.9 0.5 1e-81 274.9 0.5 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal RhoGEF67_u2 PF16614.5 KFP21642.1 - 1.5e-50 169.8 4.4 1.5e-50 169.8 4.4 2.7 2 1 0 2 2 2 1 Unstructured region two on RhoGEF 6 and 7 betaPIX_CC PF16523.5 KFP21642.1 - 3.3e-41 139.0 10.1 3.3e-41 139.0 10.1 3.1 4 0 0 4 4 4 1 betaPIX coiled coil RhoGEF PF00621.20 KFP21642.1 - 7.7e-32 111.0 1.1 7.7e-32 111.0 1.1 2.1 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.17 KFP21642.1 - 4.9e-18 64.5 0.2 1.1e-17 63.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP21642.1 - 2.9e-17 62.3 0.1 5.5e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP21642.1 - 1.2e-16 60.1 0.2 2.1e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain RhoGEF67_u1 PF16615.5 KFP21642.1 - 3.4e-16 59.5 2.6 3.4e-16 59.5 2.6 3.4 4 0 0 4 4 3 1 Unstructured region one on RhoGEF 6 and 7 PH PF00169.29 KFP21642.1 - 4.1e-09 36.9 0.0 1e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 PH domain AKNA PF12443.8 KFP21642.1 - 0.068 13.8 4.9 0.68 10.6 0.1 3.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor GlutR_dimer PF00745.20 KFP21642.1 - 0.19 12.2 3.5 0.7 10.4 3.5 2.0 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain TCTP PF00838.17 KFP21642.1 - 0.25 11.6 2.9 1 9.7 0.8 2.5 2 0 0 2 2 2 0 Translationally controlled tumour protein CENP-Q PF13094.6 KFP21642.1 - 1.1 9.5 13.6 1.5 9.0 5.6 3.3 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Cnn_1N PF07989.11 KFP21642.1 - 2 8.6 8.9 0.26 11.5 3.5 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FCH PF00611.23 KFP21642.1 - 6.7 7.1 8.1 0.93 9.8 0.4 3.2 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Ank_2 PF12796.7 KFP21643.1 - 1.9e-24 86.0 0.6 1.1e-12 48.4 0.3 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP21643.1 - 4.2e-16 59.1 0.3 9.1e-08 32.5 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP21643.1 - 5.5e-12 45.7 0.3 9.4e-07 29.0 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP21643.1 - 1.7e-11 44.0 0.7 0.00028 21.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KFP21643.1 - 2.8e-09 36.5 0.0 0.0049 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat tRNA-synt_1e PF01406.19 KFP21644.1 - 1.1e-98 330.3 0.4 1.4e-98 330.0 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFP21644.1 - 7.3e-08 31.6 1.2 0.00024 20.0 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFP21644.1 - 0.00037 18.9 0.0 0.00049 18.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KFP21644.1 - 0.0018 18.7 0.0 0.0046 17.4 0.0 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KFP21644.1 - 0.049 12.5 0.5 0.096 11.6 0.1 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (K) Carb_kinase PF01256.17 KFP21645.1 - 4.6e-56 190.0 0.0 5.7e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KFP21645.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Suc_Fer-like PF06999.12 KFP21645.1 - 0.047 13.6 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Ras PF00071.22 KFP21646.1 - 2.8e-14 53.0 0.0 1e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFP21646.1 - 2.1e-05 24.7 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP21646.1 - 0.027 13.9 0.0 0.037 13.5 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family C4 PF01413.19 KFP21647.1 - 1.2e-83 276.8 2.8 1e-45 154.7 0.1 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 KFP21648.1 - 2e-29 101.1 71.5 4.5e-10 39.1 17.7 4.1 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KFP21650.1 - 5.6e-201 650.6 764.4 5.7e-10 38.8 25.6 27.3 5 4 20 25 25 25 24 Collagen triple helix repeat (20 copies) C4 PF01413.19 KFP21650.1 - 8.5e-83 274.1 2.7 4.9e-44 149.2 0.3 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen PX PF00787.24 KFP21652.1 - 5.5e-19 68.2 0.8 1.7e-18 66.7 0.8 1.9 1 0 0 1 1 1 1 PX domain PLDc PF00614.22 KFP21652.1 - 1.2e-15 56.9 1.8 6.2e-08 32.5 0.1 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFP21652.1 - 3.1e-14 53.0 0.3 1.3e-08 34.8 0.1 3.0 2 1 0 2 2 2 2 PLD-like domain PH PF00169.29 KFP21652.1 - 6.5e-08 33.0 0.1 2.3e-07 31.3 0.1 2.0 1 0 0 1 1 1 1 PH domain DUF3785 PF12653.7 KFP21652.1 - 0.076 13.1 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) CNH PF00780.22 KFP21653.1 - 2.1e-60 204.6 0.0 3.1e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KFP21653.1 - 7.3e-55 186.2 0.0 1.8e-54 184.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21653.1 - 5.9e-42 143.7 0.0 9.9e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3040 PF11239.8 KFP21653.1 - 0.21 11.9 0.2 0.64 10.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.24 KFP21654.1 - 6.1e-151 503.3 24.9 7.5e-151 503.0 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP21654.1 - 4.2e-21 75.3 38.3 1.6e-16 60.2 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-5a PF01287.20 KFP21655.1 - 1e-27 96.0 0.2 1.5e-27 95.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFP21655.1 - 0.004 17.2 0.4 0.0064 16.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Ribosomal_L22e PF01776.17 KFP21656.1 - 9.6e-45 151.4 5.3 2.4e-44 150.2 5.3 1.5 1 1 0 1 1 1 1 Ribosomal L22e protein family AA_permease_2 PF13520.6 KFP21658.1 - 5e-46 157.4 57.4 2.6e-45 155.1 38.0 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KFP21658.1 - 4.1e-36 124.6 36.9 4.1e-36 124.6 36.9 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KFP21658.1 - 1.7e-20 72.8 9.9 1.7e-20 72.8 9.9 4.5 4 0 0 4 4 4 1 C-terminus of AA_permease PMP22_Claudin PF00822.20 KFP21659.1 - 2.8e-20 72.8 11.2 3.9e-20 72.4 11.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 KFP21659.1 - 4.7e-05 23.2 14.1 0.0051 16.6 14.1 2.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ski_Sno PF02437.17 KFP21660.1 - 4.8e-44 148.5 1.5 1.3e-43 147.2 1.5 1.7 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 KFP21660.1 - 1e-36 125.0 4.1 2.8e-36 123.6 4.1 1.8 1 0 0 1 1 1 1 c-SKI Smad4 binding domain DUF489 PF04356.12 KFP21660.1 - 1.2 9.1 11.6 0.48 10.4 7.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Pkinase PF00069.25 KFP21661.1 - 2.6e-67 227.0 0.0 3.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21661.1 - 2.5e-34 118.8 0.0 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KFP21661.1 - 4.4e-15 55.3 9.4 8.9e-15 54.3 9.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 KFP21661.1 - 8.5e-11 41.6 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.24 KFP21661.1 - 1.8e-05 25.4 2.3 5.3e-05 23.8 2.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KFP21661.1 - 4.1e-05 23.0 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP21661.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 KFP21661.1 - 0.015 15.6 2.8 0.033 14.5 2.8 1.5 1 0 0 1 1 1 0 C1 domain APH PF01636.23 KFP21661.1 - 0.03 14.2 0.0 0.094 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFP21661.1 - 0.031 13.9 0.1 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP21661.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_q2 PF00420.24 KFP21662.1 - 1 9.0 8.0 0.094 12.4 1.4 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Sec62 PF03839.16 KFP21664.1 - 4e-77 258.6 4.0 4e-77 258.6 4.0 2.3 1 1 1 2 2 2 1 Translocation protein Sec62 DEP PF00610.21 KFP21664.1 - 0.011 15.8 0.2 0.029 14.4 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ctr PF04145.15 KFP21664.1 - 0.38 11.4 0.1 0.38 11.4 0.1 2.6 2 1 0 2 2 2 0 Ctr copper transporter family SAM_1 PF00536.30 KFP21665.1 - 9.4e-13 48.4 0.0 1.8e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP21665.1 - 5.7e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP21665.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Presenilin PF01080.17 KFP21665.1 - 0.25 10.1 0.2 0.29 9.8 0.2 1.2 1 0 0 1 1 1 0 Presenilin LRR_4 PF12799.7 KFP21666.1 - 7.4e-18 64.4 39.8 0.0029 18.0 2.5 9.1 2 1 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP21666.1 - 1.7e-15 55.6 37.5 0.02 14.9 0.1 13.8 14 0 0 14 14 14 6 Leucine Rich repeat LRR_1 PF00560.33 KFP21666.1 - 1.2e-07 31.2 40.8 3.7 8.5 0.1 13.1 14 1 0 14 14 14 4 Leucine Rich Repeat LRR_8 PF13855.6 KFP21666.1 - 9.7e-06 25.3 40.1 0.21 11.4 0.9 9.8 4 2 5 10 10 10 7 Leucine rich repeat LRR_6 PF13516.6 KFP21667.1 - 9.4e-37 121.9 12.9 2.3e-05 24.1 0.1 8.0 7 0 0 7 7 7 7 Leucine Rich repeat LRR_4 PF12799.7 KFP21667.1 - 4.5e-05 23.7 10.9 0.0062 16.9 0.4 5.4 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP21667.1 - 0.00017 21.3 11.0 0.21 11.4 1.1 5.7 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KFP21667.1 - 0.00044 20.4 0.7 41 5.3 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich Repeat DUF3870 PF12986.7 KFP21667.1 - 0.062 13.5 0.1 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) zf-C2H2 PF00096.26 KFP21670.1 - 9.5e-50 164.4 78.0 5.2e-07 29.8 1.4 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21670.1 - 6.9e-33 110.5 73.0 0.00083 20.0 0.6 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFP21670.1 - 1e-32 111.1 71.8 2.9e-08 33.8 1.2 11.8 12 0 0 12 12 11 6 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFP21670.1 - 1.4e-13 50.5 64.4 8.8e-05 22.4 0.2 10.1 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP21670.1 - 2.7e-11 43.4 56.7 0.0027 17.9 0.8 10.9 11 0 0 11 11 11 6 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFP21670.1 - 1.9e-06 27.5 61.9 4.3e-05 23.2 2.4 9.1 9 1 0 9 9 9 5 C2H2-type zinc-finger domain zf-BED PF02892.15 KFP21670.1 - 0.00064 19.7 0.5 0.00064 19.7 0.5 7.7 3 3 4 7 7 7 2 BED zinc finger zf-C2H2_8 PF15909.5 KFP21670.1 - 0.0015 18.8 39.8 0.11 12.9 7.5 5.8 2 1 3 5 5 5 3 C2H2-type zinc ribbon GAGA PF09237.11 KFP21670.1 - 0.0068 16.2 19.2 2.5 8.0 0.2 5.7 3 1 2 5 5 5 3 GAGA factor Zn-ribbon_8 PF09723.10 KFP21670.1 - 0.0081 16.3 1.6 0.0081 16.3 1.6 7.9 7 2 0 7 7 7 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 KFP21670.1 - 0.017 14.9 57.4 0.05 13.4 0.8 8.5 10 0 0 10 10 9 0 zinc-finger C2H2-type zf-met PF12874.7 KFP21670.1 - 0.034 14.5 48.2 0.37 11.3 0.2 9.6 9 0 0 9 9 9 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 KFP21670.1 - 0.34 10.8 0.0 0.34 10.8 0.0 6.8 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KFP21670.1 - 7.4 7.4 45.0 0.23 12.2 0.6 6.4 2 2 6 8 8 8 0 zinc-ribbon family DUF4525 PF15027.6 KFP21672.1 - 0.35 10.6 3.9 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) FlaC_arch PF05377.11 KFP21672.1 - 0.66 10.4 11.2 0.6 10.5 2.0 4.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) PI_PP_I PF18363.1 KFP21672.1 - 2.8 8.2 7.8 0.46 10.7 2.1 2.6 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain LRR_9 PF14580.6 KFP21674.1 - 8e-06 25.5 0.5 1.6e-05 24.5 0.4 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KFP21674.1 - 3.8e-05 23.9 9.5 0.014 15.8 0.2 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP21674.1 - 0.00021 21.0 7.6 0.021 14.6 0.5 3.6 1 1 2 3 3 3 3 Leucine rich repeat fn3 PF00041.21 KFP21675.1 - 7.5e-95 311.4 1.6 4.5e-10 39.7 0.0 9.9 9 1 0 9 9 9 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP21675.1 - 7e-24 84.2 0.9 0.19 12.3 0.1 9.2 8 1 0 8 8 8 7 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KFP21675.1 - 3e-13 50.0 0.0 0.044 14.2 0.0 7.1 7 0 0 7 7 7 4 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 KFP21675.1 - 4.7e-09 36.5 5.2 3.4 8.0 0.0 7.5 8 0 0 8 8 8 3 Interferon-alpha/beta receptor, fibronectin type III fn3_2 PF16893.5 KFP21675.1 - 0.0015 18.6 0.0 3.3 7.9 0.0 4.8 5 0 0 5 5 5 1 Fibronectin type III domain CBM_4_9 PF02018.17 KFP21675.1 - 0.097 12.9 0.0 11 6.3 0.0 3.5 4 0 0 4 4 4 0 Carbohydrate binding domain TNF PF00229.18 KFP21676.1 - 2.7e-41 140.5 0.1 4.1e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.21 KFP21676.1 - 0.061 13.5 0.7 0.48 10.6 0.1 2.2 1 1 1 2 2 2 0 C1q domain Abhydrolase_3 PF07859.13 KFP21677.1 - 2.4e-54 184.4 0.1 1.9e-39 135.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFP21677.1 - 1.7e-07 30.5 0.0 2.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KFP21677.1 - 1.8e-06 27.2 0.1 0.00019 20.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 KFP21677.1 - 0.00062 19.3 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KFP21677.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PuR_N PF09182.10 KFP21677.1 - 0.023 14.6 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal AXE1 PF05448.12 KFP21677.1 - 0.053 12.2 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RhoGEF PF00621.20 KFP21678.1 - 1.2e-39 136.4 0.4 2.6e-39 135.3 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 KFP21678.1 - 2.7e-25 88.1 3.2 1.3e-18 66.7 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 KFP21678.1 - 9e-17 61.2 0.2 5.8e-07 29.8 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFP21678.1 - 0.0005 20.3 0.0 1.6 9.1 0.1 2.7 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 KFP21678.1 - 0.00062 20.1 0.0 0.018 15.4 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KFP21678.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain SKA2 PF16740.5 KFP21678.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 NYD-SP12_N PF15015.6 KFP21679.1 - 6.4e-237 787.4 0.1 7.7e-237 787.2 0.1 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_1 PF00515.28 KFP21679.1 - 0.0028 17.4 3.4 2.9 7.9 0.8 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP21679.1 - 0.0035 17.3 8.0 0.13 12.5 1.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP21679.1 - 0.0041 17.4 1.0 1.8 8.9 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat RgpF PF05045.12 KFP21679.1 - 0.013 14.3 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F EzrA PF06160.12 KFP21679.1 - 0.13 10.4 0.0 0.13 10.4 0.0 3.0 4 0 0 4 4 4 0 Septation ring formation regulator, EzrA TPR_11 PF13414.6 KFP21679.1 - 0.14 11.9 0.6 0.49 10.1 0.3 2.2 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KFP21679.1 - 0.2 12.3 5.9 1.2 9.9 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP21679.1 - 0.22 12.4 1.4 8.9 7.4 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF572 PF04502.13 KFP21679.1 - 0.31 10.6 5.7 0.64 9.6 2.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) V-set PF07686.17 KFP21681.1 - 8.5e-06 25.9 0.2 1.2e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 KFP21681.1 - 0.00064 19.9 0.2 0.001 19.2 0.2 1.3 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 I-set PF07679.16 KFP21681.1 - 0.018 15.1 0.3 0.045 13.8 0.3 1.7 1 1 0 1 1 1 0 Immunoglobulin I-set domain ig PF00047.25 KFP21681.1 - 0.057 13.6 0.3 0.11 12.7 0.2 1.6 1 1 0 1 1 1 0 Immunoglobulin domain Med17 PF10156.9 KFP21682.1 - 2.7e-08 33.0 0.3 3.9e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Thioredoxin_12 PF18400.1 KFP21682.1 - 0.048 13.5 0.8 0.094 12.6 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1907 PF08925.11 KFP21683.1 - 4.3e-123 410.2 0.0 4.9e-123 410.1 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) TAF1D PF15333.6 KFP21684.1 - 1.6e-66 224.2 23.0 5.5e-66 222.4 23.0 1.8 1 1 0 1 1 1 1 TATA box-binding protein-associated factor 1D ALMS_motif PF15309.6 KFP21685.1 - 2.9e-25 89.3 25.7 5e-25 88.6 25.7 1.3 1 0 0 1 1 1 1 ALMS motif AAT PF03417.16 KFP21685.1 - 0.073 12.7 0.1 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Stimulus_sens_1 PF13756.6 KFP21685.1 - 0.27 11.8 3.7 9.4 6.9 0.5 2.3 2 0 0 2 2 2 0 Stimulus-sensing domain FlxA PF14282.6 KFP21685.1 - 2.2 8.3 14.5 0.082 12.9 5.0 2.5 1 1 1 2 2 2 0 FlxA-like protein DUF45 PF01863.17 KFP21685.1 - 2.4 8.1 14.3 27 4.7 14.3 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF45 ISG65-75 PF11727.8 KFP21689.1 - 0.093 11.9 6.4 0.1 11.8 6.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein FUSC-like PF12805.7 KFP21689.1 - 0.17 10.9 6.1 0.2 10.7 6.1 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS vATP-synt_E PF01991.18 KFP21689.1 - 0.24 10.8 12.3 0.27 10.6 12.3 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit HSCB_C PF07743.13 KFP21689.1 - 0.34 11.4 12.5 0.54 10.8 11.0 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4519 PF15012.6 KFP21690.1 - 6.8e-29 99.8 4.5 7.5e-29 99.7 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.6 KFP21690.1 - 0.00044 20.1 0.1 0.00047 20.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Orf78 PF06024.12 KFP21690.1 - 0.00078 19.7 0.0 0.00081 19.7 0.0 1.0 1 0 0 1 1 1 1 Orf78 (ac78) DUF2232 PF09991.9 KFP21690.1 - 0.0024 17.1 0.0 0.0027 16.9 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) FTCD_C PF04961.12 KFP21690.1 - 0.0036 17.1 0.1 0.0038 17.0 0.1 1.0 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase CrgA PF06781.12 KFP21690.1 - 0.0092 16.0 0.2 0.01 15.9 0.2 1.0 1 0 0 1 1 1 1 Cell division protein CrgA DUF2208 PF09973.9 KFP21690.1 - 0.016 14.9 0.0 0.016 14.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Vma12 PF11712.8 KFP21690.1 - 0.031 14.3 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5305 PF17231.2 KFP21690.1 - 0.039 13.4 0.1 0.041 13.3 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 KFP21690.1 - 0.048 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EMC3_TMCO1 PF01956.16 KFP21690.1 - 0.051 13.3 0.1 0.057 13.1 0.1 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3671 PF12420.8 KFP21690.1 - 0.051 13.6 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF3899 PF13038.6 KFP21690.1 - 0.062 13.8 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF515 PF04415.12 KFP21690.1 - 0.063 11.7 0.2 0.064 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DotU PF09850.9 KFP21690.1 - 0.065 13.0 0.1 0.069 12.9 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2116 PF09889.9 KFP21690.1 - 0.13 12.3 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) CEP63 PF17045.5 KFP21691.1 - 5.1e-64 216.8 45.3 5.1e-64 216.8 45.3 4.5 3 2 0 3 3 3 1 Centrosomal protein of 63 kDa Tup_N PF08581.10 KFP21691.1 - 0.012 15.9 7.5 0.012 15.9 7.5 7.7 5 3 1 7 7 7 0 Tup N-terminal RrnaAD PF00398.20 KFP21692.1 - 4.9e-55 186.4 0.0 5.9e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFP21692.1 - 9.9e-08 32.6 0.0 4e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP21692.1 - 0.00012 22.7 0.0 0.00069 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP21692.1 - 0.00076 20.2 0.0 0.0028 18.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP21692.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP21692.1 - 0.0027 17.5 0.0 0.0058 16.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KFP21692.1 - 0.0059 16.4 0.1 0.0095 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KFP21692.1 - 0.016 15.2 0.0 0.033 14.1 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFP21692.1 - 0.021 14.3 0.0 0.055 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase UPF0020 PF01170.18 KFP21692.1 - 0.03 14.0 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 DREV PF05219.12 KFP21692.1 - 0.036 13.2 0.0 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase MTS PF05175.14 KFP21692.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 KFP21692.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein Ubie_methyltran PF01209.18 KFP21692.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Kinesin PF00225.23 KFP21693.1 - 9e-93 310.8 0.1 9e-93 310.8 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFP21693.1 - 1.1e-14 54.6 0.1 5e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 KFP21693.1 - 2.7 8.1 14.0 0.78 9.8 7.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 KFP21693.1 - 3.4 7.7 7.5 10 6.2 0.5 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain UPF0542 PF15086.6 KFP21694.1 - 2.4e-30 104.3 2.4 2.7e-30 104.1 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 7TM_GPCR_Sru PF10322.9 KFP21694.1 - 0.13 11.6 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Pkinase_Tyr PF07714.17 KFP21695.1 - 1.9e-91 305.9 0.0 2.3e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP21695.1 - 9e-45 153.1 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 KFP21695.1 - 0.00093 19.0 0.1 0.0028 17.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP21695.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain SH3_1 PF00018.28 KFP21695.1 - 0.0044 16.6 0.2 0.019 14.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFP21695.1 - 0.0057 16.3 0.3 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.23 KFP21695.1 - 0.044 13.7 0.1 0.29 11.0 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFP21695.1 - 0.22 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KFP21695.1 - 0.23 10.8 0.1 0.53 9.6 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM76 PF16046.5 KFP21696.1 - 5.5e-82 275.5 29.0 6.4e-82 275.3 29.0 1.0 1 0 0 1 1 1 1 FAM76 protein GHL13 PF14883.6 KFP21696.1 - 0.00069 18.8 3.2 0.0013 17.9 3.2 1.4 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 KASH_CCD PF14662.6 KFP21696.1 - 0.03 14.1 3.5 0.03 14.1 3.5 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH MPS2 PF17060.5 KFP21696.1 - 0.091 12.0 11.3 0.33 10.2 11.3 1.8 1 1 0 1 1 1 0 Monopolar spindle protein 2 CorA PF01544.18 KFP21696.1 - 0.13 11.5 3.2 0.17 11.2 3.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fibin PF15819.5 KFP21696.1 - 0.56 9.9 7.9 9.1 6.0 0.1 2.2 2 0 0 2 2 2 0 Fin bud initiation factor homologue Jnk-SapK_ap_N PF09744.9 KFP21696.1 - 0.99 9.6 18.8 0.26 11.5 9.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 KFP21696.1 - 2.2 8.8 10.8 0.58 10.7 7.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DZR PF12773.7 KFP21696.1 - 3.7 7.7 20.6 0.52 10.4 12.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon PSII_Pbs31 PF18240.1 KFP21696.1 - 3.8 8.0 6.6 0.81 10.2 1.9 2.1 2 0 0 2 2 2 0 Photosystem II Psb31 protein TipAS PF07739.13 KFP21696.1 - 4.4 7.9 9.7 0.61 10.6 5.1 2.0 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain RCC1 PF00415.18 KFP21697.1 - 5e-47 158.3 13.3 6.2e-13 49.2 0.3 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFP21697.1 - 8.4e-13 47.8 23.3 0.0034 17.1 0.2 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat TFIIS_M PF07500.14 KFP21698.1 - 4.7e-38 130.1 0.3 9.7e-38 129.1 0.3 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFP21698.1 - 1.6e-18 66.2 7.1 3.2e-18 65.3 7.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFP21698.1 - 1e-08 35.1 0.8 5.8e-08 32.6 0.8 2.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Apt1 PF10351.9 KFP21698.1 - 0.11 11.3 5.1 0.14 11.0 5.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF913 PF06025.12 KFP21698.1 - 0.85 8.5 3.7 1.4 7.8 3.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ArfGap PF01412.18 KFP21699.1 - 2.8e-35 120.9 0.1 1.8e-34 118.3 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KFP21699.1 - 3.4e-18 66.2 9.7 6.6e-18 65.3 9.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 KFP21699.1 - 5.2e-14 52.6 1.2 2.8e-07 31.0 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) PH PF00169.29 KFP21699.1 - 1.1e-11 45.1 0.7 4.1e-11 43.3 0.4 2.1 2 0 0 2 2 2 1 PH domain Ank_3 PF13606.6 KFP21699.1 - 1.5e-07 31.2 0.3 0.03 14.8 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFP21699.1 - 4.2e-07 30.4 0.2 2.8e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP21699.1 - 4.5e-07 30.0 0.5 6.2e-06 26.4 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP21699.1 - 4.9e-05 23.6 1.1 0.00057 20.2 0.3 3.0 2 1 1 3 3 3 1 Ankyrin repeat PH_9 PF15410.6 KFP21699.1 - 0.00054 20.3 0.1 0.93 9.9 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain DUF3287 PF11690.8 KFP21699.1 - 0.014 15.1 0.2 0.038 13.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) PH_3 PF14593.6 KFP21699.1 - 0.036 14.2 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_2 PF08458.10 KFP21699.1 - 0.037 14.4 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 1 0 Plant pleckstrin homology-like region PH_13 PF16652.5 KFP21699.1 - 0.097 12.5 1.6 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2333 PF10095.9 KFP21699.1 - 0.15 11.1 0.6 0.29 10.1 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) HLH PF00010.26 KFP21701.1 - 3.3e-12 46.2 0.0 4.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YTH PF04146.15 KFP21702.1 - 9.9e-42 142.7 0.5 4.2e-41 140.7 0.5 1.9 1 1 0 1 1 1 1 YT521-B-like domain SAND PF01342.21 KFP21703.1 - 1e-23 82.8 0.2 1.9e-23 81.9 0.2 1.5 1 0 0 1 1 1 1 SAND domain TFIID_20kDa PF03847.13 KFP21704.1 - 3.6e-36 123.5 2.8 5e-36 123.0 2.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KFP21704.1 - 6.6e-06 26.3 0.2 1e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP21704.1 - 3.2e-05 24.3 1.1 3.6e-05 24.1 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KFP21704.1 - 8.8e-05 22.6 0.2 0.00019 21.5 0.1 1.6 1 1 1 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KFP21704.1 - 0.0056 16.8 0.1 0.0096 16.0 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF4 PF05236.14 KFP21704.1 - 0.0088 15.8 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Ras PF00071.22 KFP21705.1 - 3.2e-26 91.9 0.0 3.5e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21705.1 - 2.8e-05 24.3 0.0 8.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Peptidase_C80 PF11713.8 KFP21705.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase C80 family Trnau1ap PF17654.1 KFP21706.1 - 1.7e-42 144.5 20.0 2.2e-42 144.1 20.0 1.2 1 0 0 1 1 1 1 Selenocysteine tRNA 1 associated proteins RRM_1 PF00076.22 KFP21706.1 - 5.2e-13 48.6 0.0 7.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_knot PF00007.22 KFP21707.1 - 8.2e-13 48.6 9.3 8.2e-13 48.6 9.3 3.7 4 0 0 4 4 4 1 Cystine-knot domain IGFBP PF00219.18 KFP21707.1 - 1.3e-10 41.7 21.3 1.3e-10 41.7 21.3 5.9 3 2 1 4 4 4 1 Insulin-like growth factor binding protein VWC PF00093.18 KFP21707.1 - 4.4e-08 33.3 10.3 4.4e-08 33.3 10.3 5.3 4 3 0 4 4 4 1 von Willebrand factor type C domain TSP_1 PF00090.19 KFP21707.1 - 1.7e-06 28.1 7.2 2.6e-05 24.3 7.2 3.1 1 0 0 1 1 1 1 Thrombospondin type 1 domain 4_1_CTD PF05902.13 KFP21708.1 - 9.5e-49 163.9 13.8 2.6e-48 162.5 13.8 1.8 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.10 KFP21708.1 - 3.2e-25 88.4 0.0 8e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SAB PF04382.13 KFP21708.1 - 3.4e-23 81.5 2.9 1.1e-22 79.9 2.9 2.0 1 0 0 1 1 1 1 SAB domain FERM_M PF00373.18 KFP21708.1 - 2.7e-19 69.7 1.9 3.7e-19 69.3 0.0 2.2 2 1 0 2 2 2 1 FERM central domain FA PF08736.11 KFP21708.1 - 3.6e-19 68.6 3.3 1.2e-18 66.9 3.3 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_N PF09379.10 KFP21708.1 - 5.2e-18 64.7 0.2 1.8e-17 63.1 0.1 2.0 2 0 0 2 2 2 1 FERM N-terminal domain YAcAr PF10686.9 KFP21708.1 - 0.14 12.2 0.1 0.42 10.6 0.1 1.8 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Wound_ind PF08186.11 KFP21708.1 - 0.36 11.3 3.4 0.16 12.4 0.4 2.1 2 0 0 2 2 2 0 Wound-inducible basic protein family MBT PF02820.18 KFP21709.1 - 5.6e-94 308.5 1.2 4e-30 104.0 0.0 3.2 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KFP21709.1 - 2e-11 43.9 9.8 3.7e-11 43.0 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2HC type Tudor-knot PF11717.8 KFP21709.1 - 0.0082 16.0 4.4 0.057 13.3 0.5 3.0 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Glyco_hydro_2_N PF02837.18 KFP21709.1 - 0.021 14.8 0.0 9.8 6.1 0.0 2.7 3 0 0 3 3 3 0 Glycosyl hydrolases family 2, sugar binding domain RRM_1 PF00076.22 KFP21711.1 - 6.8e-22 77.1 0.0 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP21711.1 - 9.8e-05 22.3 0.0 9.8e-05 22.3 0.0 2.6 2 1 0 2 2 2 1 RNA binding motif ADH_zinc_N PF00107.26 KFP21712.1 - 1.1e-20 73.9 0.0 1.7e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP21712.1 - 7.7e-09 35.4 0.1 2e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFP21712.1 - 4e-08 34.4 0.0 7.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 KFP21712.1 - 0.053 14.0 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 CoA binding domain DUF4265 PF14085.6 KFP21712.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Mtp PF03821.16 KFP21714.1 - 2.7e-104 347.8 12.1 3.1e-104 347.7 12.1 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 KFP21714.1 - 7.2e-05 23.4 15.3 0.011 16.4 8.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4728) CybS PF05328.12 KFP21714.1 - 0.043 13.5 2.3 1.5 8.5 0.2 2.5 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit Sigma_reg_N PF13800.6 KFP21714.1 - 0.47 10.8 3.9 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal UPF0139 PF03669.13 KFP21714.1 - 5 7.1 6.1 44 4.0 0.3 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) Syndecan PF01034.20 KFP21715.1 - 1e-23 83.0 0.2 1.6e-23 82.3 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain PUF PF00806.19 KFP21716.1 - 1.1e-73 239.0 8.3 5.4e-09 35.2 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KFP21716.1 - 0.041 14.2 0.6 4.9 7.5 0.1 3.6 1 1 1 3 3 3 0 CPL (NUC119) domain sCache_2 PF17200.4 KFP21716.1 - 0.083 12.7 0.0 55 3.6 0.0 3.7 4 0 0 4 4 4 0 Single Cache domain 2 Importin_rep_3 PF18806.1 KFP21716.1 - 0.15 12.1 0.2 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat Mt_ATP-synt_B PF05405.14 KFP21716.1 - 0.79 9.3 2.7 8.7 5.9 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) K_channel_TID PF07941.11 KFP21716.1 - 2.5 8.6 13.5 0.9 10.0 4.5 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NKAIN PF05640.14 KFP21717.1 - 3.1e-80 268.3 7.4 3.4e-80 268.2 7.4 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein WD40 PF00400.32 KFP21718.1 - 3e-51 170.3 5.2 4.3e-07 30.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21718.1 - 4.4e-16 59.0 0.1 0.0019 18.5 0.0 5.7 3 3 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP21718.1 - 3.2e-09 37.0 0.2 0.0057 16.6 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP21718.1 - 5.8e-06 25.5 0.1 5 6.0 0.0 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFP21718.1 - 0.00033 19.3 0.1 0.29 9.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KFP21718.1 - 0.001 17.8 5.3 2.7 6.5 0.0 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KFP21718.1 - 0.0073 15.7 0.0 1.2 8.4 0.1 2.3 1 1 1 2 2 2 2 WD40-like domain PD40 PF07676.12 KFP21718.1 - 0.074 13.0 0.0 0.89 9.6 0.1 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat S1 PF00575.23 KFP21719.1 - 1.4e-07 31.8 0.1 2.9e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain zf-CCHC_3 PF13917.6 KFP21719.1 - 0.0012 18.8 1.0 0.0021 18.0 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KFP21719.1 - 0.0073 16.3 4.6 0.015 15.3 4.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Lipocalin PF00061.23 KFP21720.1 - 1.6e-19 70.5 1.6 1.7e-19 70.5 1.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KFP21720.1 - 0.0021 18.0 0.3 0.0025 17.7 0.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Myosin_N PF02736.19 KFP21720.1 - 0.24 11.3 3.2 0.48 10.3 0.3 2.6 2 1 2 4 4 4 0 Myosin N-terminal SH3-like domain Serinc PF03348.15 KFP21721.1 - 4.8e-158 526.6 11.8 5.5e-158 526.4 11.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Pox_A14 PF05767.12 KFP21721.1 - 2.3 8.5 6.2 2 8.6 1.7 2.9 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF5134 PF17197.4 KFP21721.1 - 4.3 7.2 9.4 1.4 8.8 1.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) Phage_fiber_2 PF03406.13 KFP21723.1 - 0.18 11.4 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Phage tail fibre repeat Endothelin PF00322.17 KFP21724.1 - 5.6e-21 73.8 7.2 5.6e-21 73.8 7.2 2.5 3 0 0 3 3 3 2 Endothelin family SLED PF12140.8 KFP21727.1 - 3.6e-37 127.3 0.1 6e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 SLED domain SAM_1 PF00536.30 KFP21727.1 - 8.8e-17 61.3 0.1 1.7e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RBR PF17208.3 KFP21727.1 - 6.7e-11 42.7 16.5 2e-10 41.2 16.5 1.8 1 0 0 1 1 1 1 RNA binding Region SAM_2 PF07647.17 KFP21727.1 - 2e-07 31.0 0.0 4.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP21727.1 - 0.00042 20.2 0.0 0.00073 19.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain CTP_synth_N PF06418.14 KFP21728.1 - 8.3e-128 425.3 0.1 1e-127 424.9 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFP21728.1 - 1.8e-54 184.4 0.0 3.1e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFP21728.1 - 2.3e-09 37.3 0.0 4.9e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Transket_pyr PF02779.24 KFP21728.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain CbiA PF01656.23 KFP21728.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4462 PF14692.6 KFP21730.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) CITED PF04487.12 KFP21733.1 - 7e-80 268.3 14.4 7.9e-80 268.2 14.4 1.0 1 0 0 1 1 1 1 CITED Med15 PF09606.10 KFP21733.1 - 8.4 4.9 25.2 10 4.7 25.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Syntaxin_2 PF14523.6 KFP21734.1 - 2e-24 85.9 15.5 2.9e-24 85.3 8.9 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KFP21734.1 - 4.8e-18 64.9 0.3 9.7e-18 63.9 0.3 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFP21734.1 - 1.9e-12 47.3 14.2 1.9e-12 47.3 14.2 1.5 2 1 0 2 2 2 1 Syntaxin YxiJ PF14176.6 KFP21734.1 - 0.018 15.5 0.1 0.04 14.4 0.1 1.5 1 0 0 1 1 1 0 YxiJ-like protein Sortilin-Vps10 PF15902.5 KFP21734.1 - 0.065 12.0 0.1 0.086 11.6 0.1 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, MCU PF04678.13 KFP21734.1 - 1.1 9.4 9.0 0.1 12.7 0.4 2.2 2 1 0 2 2 2 0 Mitochondrial calcium uniporter ABC_tran_CTD PF16326.5 KFP21734.1 - 2.2 8.6 19.8 1.2 9.5 1.4 4.2 2 2 1 3 3 3 0 ABC transporter C-terminal domain YlqD PF11068.8 KFP21734.1 - 2.9 8.2 19.5 1.6 9.1 11.5 2.4 1 1 1 2 2 2 0 YlqD protein Noelin-1 PF12308.8 KFP21734.1 - 5.9 6.9 7.4 8 6.5 0.4 2.8 2 2 0 2 2 2 0 Neurogenesis glycoprotein RPA_C PF08784.11 KFP21735.1 - 1.1e-23 83.8 0.1 2.6e-23 82.6 0.1 1.6 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFP21735.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KFP21735.1 - 0.0067 16.2 0.1 0.58 10.0 0.0 2.3 1 1 1 2 2 2 1 RecQ-mediated genome instability protein 2 TFA2_Winged_2 PF18121.1 KFP21735.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.6 1 1 0 1 1 1 0 TFA2 Winged helix domain 2 Stn1 PF10451.9 KFP21735.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 LexA_DNA_bind PF01726.16 KFP21735.1 - 0.029 14.1 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain Metallophos PF00149.28 KFP21736.1 - 1.9e-10 41.6 1.5 3.4e-10 40.8 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XK-related PF09815.9 KFP21737.1 - 2.1e-73 247.4 14.0 2.4e-73 247.2 14.0 1.0 1 0 0 1 1 1 1 XK-related protein 7tm_1 PF00001.21 KFP21739.1 - 1.2e-38 132.9 27.4 1.2e-38 132.9 27.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF5305 PF17231.2 KFP21739.1 - 0.032 13.6 1.0 0.064 12.6 0.1 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5305) 7TM_GPCR_Str PF10326.9 KFP21739.1 - 6.5 6.0 29.6 1e+02 2.1 29.5 2.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DnaJ PF00226.31 KFP21740.1 - 7.7e-17 61.2 1.3 7.7e-17 61.2 1.3 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3089 PF11288.8 KFP21740.1 - 0.16 11.5 1.2 0.26 10.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) DivIC PF04977.15 KFP21741.1 - 0.002 17.8 5.4 0.0031 17.2 5.4 1.4 1 1 0 1 1 1 1 Septum formation initiator Cep57_MT_bd PF06657.13 KFP21741.1 - 0.0034 17.8 7.6 0.0071 16.8 7.6 1.5 1 1 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.10 KFP21741.1 - 0.012 15.8 3.5 0.013 15.7 3.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_lysis PF03245.13 KFP21741.1 - 0.015 15.4 3.6 0.017 15.3 3.6 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Csm1_N PF18504.1 KFP21741.1 - 0.025 14.9 3.4 0.025 14.9 3.4 1.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Val_tRNA-synt_C PF10458.9 KFP21741.1 - 0.03 14.6 2.9 0.03 14.6 2.9 2.0 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm FlaC_arch PF05377.11 KFP21741.1 - 0.034 14.5 1.4 0.037 14.4 1.4 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 KFP21741.1 - 0.04 14.3 3.8 0.042 14.2 3.8 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF16 PF01519.16 KFP21741.1 - 0.06 13.8 3.4 0.062 13.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 KFP21741.1 - 0.064 13.2 8.9 0.069 13.1 8.9 1.1 1 0 0 1 1 1 0 Prefoldin subunit THOC7 PF05615.13 KFP21741.1 - 0.07 13.4 8.4 0.074 13.3 8.4 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 Borrelia_P83 PF05262.11 KFP21741.1 - 0.074 11.5 9.2 0.074 11.5 9.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein XhlA PF10779.9 KFP21741.1 - 0.076 13.2 5.9 0.086 13.1 5.9 1.2 1 0 0 1 1 1 0 Haemolysin XhlA DUF1192 PF06698.11 KFP21741.1 - 0.077 13.1 6.5 0.28 11.3 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Bcr-Abl_Oligo PF09036.10 KFP21741.1 - 0.077 13.0 3.3 0.088 12.8 3.3 1.2 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain PHM7_cyt PF14703.6 KFP21741.1 - 0.12 12.7 4.1 0.11 12.8 4.1 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF812 PF05667.11 KFP21741.1 - 0.13 11.1 7.3 0.13 11.1 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Lipoprotein_20 PF13942.6 KFP21741.1 - 0.14 12.1 6.2 0.16 11.9 6.2 1.0 1 0 0 1 1 1 0 YfhG lipoprotein DUF3450 PF11932.8 KFP21741.1 - 0.2 11.0 3.1 0.19 11.0 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KFP21741.1 - 0.21 10.4 7.4 0.21 10.5 7.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3782 PF12644.7 KFP21741.1 - 0.24 11.6 3.0 0.3 11.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) OmpH PF03938.14 KFP21741.1 - 0.25 11.7 5.2 0.25 11.7 5.2 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sipho_Gp157 PF05565.11 KFP21741.1 - 0.3 11.1 7.3 0.32 11.0 7.3 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4407 PF14362.6 KFP21741.1 - 0.32 10.3 3.4 0.31 10.4 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KFP21741.1 - 0.33 10.2 4.8 0.32 10.2 4.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.6 KFP21741.1 - 0.33 11.4 12.4 0.37 11.2 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IATP PF04568.12 KFP21741.1 - 0.33 11.4 13.8 0.096 13.1 11.3 1.4 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Dzip-like_N PF13815.6 KFP21741.1 - 0.38 10.7 6.4 0.43 10.6 6.4 1.0 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF883 PF05957.13 KFP21741.1 - 0.61 10.7 4.1 0.61 10.7 4.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4140 PF13600.6 KFP21741.1 - 0.61 10.6 4.4 0.7 10.4 4.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 KFP21741.1 - 0.62 9.9 8.6 0.69 9.7 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IMD PF08397.11 KFP21741.1 - 0.68 9.3 9.5 0.68 9.3 9.5 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain HAUS5 PF14817.6 KFP21741.1 - 0.69 8.6 7.3 0.71 8.6 7.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 CCDC73 PF15818.5 KFP21741.1 - 0.88 7.3 9.8 0.88 7.3 9.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family ABC_tran_Xtn PF12848.7 KFP21741.1 - 1 9.4 9.6 1.5 8.9 9.6 1.3 1 0 0 1 1 1 0 ABC transporter UPF0242 PF06785.11 KFP21741.1 - 1.3 9.1 9.1 1.3 9.1 9.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KFP21741.1 - 1.3 8.0 9.7 1.3 8.0 9.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF612 PF04747.12 KFP21741.1 - 5.3 6.0 11.3 5.1 6.1 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 LCD1 PF09798.9 KFP21741.1 - 5.4 5.4 10.5 5.2 5.5 10.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4337 PF14235.6 KFP21741.1 - 6.5 6.9 6.6 6.4 6.9 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RRP7 PF12923.7 KFP21741.1 - 8.4 6.6 14.0 9.7 6.3 1.2 2.0 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain LapA_dom PF06305.11 KFP21741.1 - 8.5 6.3 7.6 52 3.8 7.6 2.2 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RRM_1 PF00076.22 KFP21742.1 - 5.1e-45 151.2 1.6 1.6e-15 56.6 0.4 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 KFP21742.1 - 5e-32 109.7 0.1 1.2e-31 108.4 0.1 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_7 PF16367.5 KFP21742.1 - 4.6e-10 39.5 0.2 0.006 16.7 0.0 4.4 2 2 1 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 KFP21742.1 - 1.3e-06 28.0 0.0 2.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFP21742.1 - 0.00046 20.0 0.0 0.0065 16.3 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFP21742.1 - 0.00052 20.0 0.1 1.7 8.8 0.1 3.9 3 1 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 KFP21742.1 - 0.0071 16.3 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KFP21742.1 - 0.012 15.9 1.1 31 4.8 0.0 4.5 3 2 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Spo7_2_N PF15407.6 KFP21742.1 - 0.074 12.7 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 7tm_1 PF00001.21 KFP21743.1 - 4.4e-78 262.2 14.6 5.5e-78 261.9 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP21743.1 - 1.9e-11 43.9 10.0 4.9e-11 42.5 10.0 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP21743.1 - 3.7e-05 23.5 12.9 3.7e-05 23.5 12.9 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP21743.1 - 0.00053 19.8 14.1 0.01 15.6 10.7 2.5 2 1 0 2 2 2 2 Olfactory receptor HD_assoc PF13286.6 KFP21744.1 - 0.035 14.6 0.3 0.2 12.2 0.3 2.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Amino_oxidase PF01593.24 KFP21745.1 - 5e-136 454.6 0.0 3.9e-135 451.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFP21745.1 - 6e-18 65.0 0.3 3.5e-17 62.5 0.0 2.4 3 0 0 3 3 2 1 SWIRM domain NAD_binding_8 PF13450.6 KFP21745.1 - 3.9e-14 52.6 0.7 8.5e-14 51.5 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFP21745.1 - 6.3e-08 32.6 0.0 3.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFP21745.1 - 3.8e-06 26.3 0.1 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFP21745.1 - 6.9e-06 25.5 0.4 1.9e-05 24.1 0.4 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFP21745.1 - 4.1e-05 22.8 0.9 8.3e-05 21.8 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFP21745.1 - 5.5e-05 23.7 0.2 5.5e-05 23.7 0.2 3.1 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFP21745.1 - 0.00091 18.6 0.3 0.0016 17.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFP21745.1 - 0.00099 17.9 0.4 0.00099 17.9 0.4 2.2 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFP21745.1 - 0.0015 17.8 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFP21745.1 - 0.0015 17.9 0.2 0.015 14.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFP21745.1 - 0.0059 16.0 2.3 0.0059 16.0 2.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFP21745.1 - 0.02 14.2 0.2 0.074 12.4 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFP21745.1 - 0.059 12.4 5.5 0.12 11.4 0.3 2.2 1 1 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFP21745.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 KFP21745.1 - 0.11 11.3 0.4 0.22 10.2 0.1 1.7 1 1 0 1 1 1 0 MCRA family IlvN PF07991.12 KFP21745.1 - 0.11 12.0 0.5 0.41 10.2 0.2 1.9 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MutS_IV PF05190.18 KFP21745.1 - 0.16 12.3 3.1 1.6 9.1 0.6 2.6 2 0 0 2 2 2 0 MutS family domain IV Snapin_Pallidin PF14712.6 KFP21745.1 - 0.58 10.6 7.2 7.7 7.0 7.2 2.4 1 1 0 1 1 1 0 Snapin/Pallidin DASH_Dad3 PF08656.10 KFP21745.1 - 0.8 9.8 3.9 7.8 6.7 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad3 DivIC PF04977.15 KFP21745.1 - 1.1 9.0 7.5 16 5.3 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF4298 PF14131.6 KFP21745.1 - 3.9 7.5 8.3 3.4 7.7 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) MRPL52 PF18699.1 KFP21745.1 - 5.7 7.2 10.9 0.25 11.6 3.8 2.4 2 1 0 2 2 2 0 Mitoribosomal protein mL52 AATF-Che1 PF13339.6 KFP21745.1 - 7.1 7.3 9.7 2.6 8.7 5.8 2.3 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor Peptidase_M48 PF01435.18 KFP21746.1 - 5.8e-71 238.3 0.0 8e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KFP21746.1 - 2.4e-68 229.6 4.3 2.4e-68 229.6 4.3 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices DUF4710 PF15828.5 KFP21746.1 - 0.048 13.8 1.7 0.24 11.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) zf-C2H2 PF00096.26 KFP21747.1 - 6.9e-08 32.5 126.5 0.0013 19.1 7.9 15.2 16 0 0 16 16 16 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21747.1 - 9.3e-05 23.0 132.2 0.13 13.2 6.3 16.0 16 0 0 16 16 16 10 C2H2-type zinc finger zf-met PF12874.7 KFP21747.1 - 0.013 15.9 1.3 0.013 15.9 1.3 9.5 10 0 0 10 10 10 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFP21747.1 - 0.22 12.2 65.0 1.4 9.6 0.1 13.0 10 3 5 15 15 15 0 FOXP coiled-coil domain DSPc PF00782.20 KFP21748.1 - 1.8e-08 34.3 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP21748.1 - 4.2e-07 29.8 0.0 6.7e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CREPT PF16566.5 KFP21757.1 - 6.9e-63 211.2 5.5 6.9e-63 211.2 5.5 1.7 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 KFP21757.1 - 2.3e-22 79.6 3.1 7.3e-22 78.0 0.0 3.1 3 1 0 3 3 3 1 RNA polymerase II-binding domain. Rep_4 PF05797.11 KFP21757.1 - 0.088 11.9 4.0 0.19 10.8 1.9 2.1 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) DUF2294 PF10057.9 KFP21757.1 - 0.098 12.8 1.7 0.42 10.8 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF2408 PF10303.9 KFP21757.1 - 2.4 8.8 9.3 2.2 8.9 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Swi5 PF07061.11 KFP21757.1 - 2.5 8.3 12.4 4 7.6 2.1 3.4 3 1 0 3 3 3 0 Swi5 Takusan PF04822.13 KFP21757.1 - 3 7.8 12.0 2.9 7.8 2.1 2.9 2 0 0 2 2 2 0 Takusan Dzip-like_N PF13815.6 KFP21757.1 - 4.4 7.3 8.7 0.5 10.3 2.6 2.3 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FemAB PF02388.16 KFP21757.1 - 4.5 6.0 7.6 0.2 10.5 1.6 1.6 2 0 0 2 2 2 0 FemAB family CTD_bind PF04818.13 KFP21758.1 - 0.0008 20.2 0.1 0.83 10.5 0.1 3.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 KFP21758.1 - 0.0028 17.5 2.0 0.37 10.6 0.0 4.5 6 0 0 6 6 6 1 VHS domain Vac14_Fab1_bd PF12755.7 KFP21758.1 - 0.0067 17.0 0.4 1.6 9.4 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFP21758.1 - 0.013 15.5 0.3 0.2 11.7 0.1 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP21758.1 - 0.015 15.5 16.2 35 5.0 0.2 8.0 8 0 0 8 8 8 0 HEAT repeat DUF5331 PF17265.2 KFP21758.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Dopey_N PF04118.14 KFP21758.1 - 0.16 11.1 0.1 0.16 11.1 0.1 3.6 3 2 2 5 5 5 0 Dopey, N-terminal Adaptin_N PF01602.20 KFP21758.1 - 0.42 9.1 6.6 9.1 4.7 0.1 3.3 3 0 0 3 3 3 0 Adaptin N terminal region DUF4211 PF13926.6 KFP21760.1 - 4.9e-32 111.0 1.2 4.9e-32 111.0 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF4196 PF13846.6 KFP21760.1 - 1.8e-14 53.9 3.9 1.8e-14 53.9 3.9 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4196) DUF2185 PF09951.9 KFP21760.1 - 1.3 8.9 4.7 0.42 10.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) MAD PF05557.13 KFP21766.1 - 2.5e-194 647.4 99.3 3e-194 647.1 99.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.18 KFP21766.1 - 2e-05 24.8 4.5 2e-05 24.8 4.5 9.6 7 3 2 9 9 9 2 TSC-22/dip/bun family DUF4200 PF13863.6 KFP21766.1 - 0.0041 17.5 10.0 0.0041 17.5 10.0 7.2 4 2 2 6 6 6 1 Domain of unknown function (DUF4200) Gag_p30 PF02093.16 KFP21767.1 - 2e-27 96.1 0.1 2.5e-27 95.8 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein DUF1743 PF08489.11 KFP21767.1 - 0.0052 16.8 0.0 0.093 12.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1743) FtsJ PF01728.19 KFP21768.1 - 4.4e-51 173.5 0.0 5.6e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KFP21768.1 - 0.0087 15.9 0.0 3.2 7.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KFP21768.1 - 0.032 14.1 0.0 0.096 12.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.28 KFP21769.1 - 3.4e-15 56.3 0.1 4.3e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain PX PF00787.24 KFP21770.1 - 1.3e-21 76.6 2.3 1.3e-21 76.6 2.3 2.0 2 1 0 2 2 2 1 PX domain Perilipin PF03036.16 KFP21770.1 - 0.0013 17.8 2.8 0.0085 15.2 2.6 2.0 2 0 0 2 2 2 1 Perilipin family EPSP_synthase PF00275.20 KFP21770.1 - 0.093 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) eIF2A PF08662.11 KFP21771.1 - 4.9e-72 241.9 7.3 2.8e-66 223.1 2.4 4.1 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFP21771.1 - 6.5e-07 29.1 0.1 1.6e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KFP21771.1 - 3.7e-06 27.1 1.8 0.4 11.0 0.0 6.0 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltr_RsmF_N PF17125.5 KFP21771.1 - 0.053 14.0 0.6 2.3 8.7 0.0 3.5 3 1 1 4 4 4 0 N-terminal domain of 16S rRNA methyltransferase RsmF Nup35_RRM PF05172.13 KFP21771.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4060 PF13269.6 KFP21771.1 - 0.17 12.0 0.1 0.7 10.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) PD40 PF07676.12 KFP21771.1 - 0.23 11.5 4.9 58 3.8 0.1 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KFP21771.1 - 0.41 11.6 5.5 3.1e+02 2.5 0.0 6.2 6 1 1 7 7 7 0 WD domain, G-beta repeat Sulfotransfer_2 PF03567.14 KFP21772.1 - 1.5e-64 218.3 3.3 2.6e-64 217.6 1.5 1.8 2 0 0 2 2 2 1 Sulfotransferase family FRB_dom PF08771.11 KFP21772.1 - 0.042 14.3 0.3 6.5 7.2 0.1 2.6 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain 7tm_1 PF00001.21 KFP21773.1 - 1.6e-43 148.9 17.5 1.8e-43 148.8 17.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP21773.1 - 3.2e-06 27.0 19.0 1.4e-05 24.9 19.0 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP21773.1 - 0.00051 19.9 8.4 0.00065 19.5 7.7 1.5 1 1 0 1 1 1 1 Olfactory receptor Serpentine_r_xa PF03383.15 KFP21773.1 - 0.0088 16.0 2.7 0.0088 16.0 2.7 2.2 1 1 1 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa DUF2434 PF10361.9 KFP21773.1 - 0.073 12.0 9.3 0.42 9.6 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2434) DUF4212 PF13937.6 KFP21773.1 - 0.16 12.3 1.9 4.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Gal-bind_lectin PF00337.22 KFP21774.1 - 1.4e-35 121.7 0.1 1.5e-35 121.6 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin Tweety PF04906.13 KFP21775.1 - 4.8e-171 568.9 10.0 5.9e-171 568.6 10.0 1.0 1 0 0 1 1 1 1 Tweety DUF4131 PF13567.6 KFP21775.1 - 0.002 17.8 4.9 0.0031 17.2 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4131) DUF2721 PF11026.8 KFP21775.1 - 0.0054 16.6 0.2 0.0054 16.6 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) Prominin PF05478.11 KFP21775.1 - 1.5 6.7 12.9 0.12 10.3 3.1 2.7 2 1 0 3 3 3 0 Prominin MgtE PF01769.16 KFP21775.1 - 3.8 7.9 7.6 4.8 7.6 0.5 2.8 3 0 0 3 3 3 0 Divalent cation transporter DUF3413 PF11893.8 KFP21775.1 - 5.5 6.1 8.0 0.25 10.5 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) SlyX PF04102.12 KFP21776.1 - 7e-05 23.4 11.0 0.0082 16.7 0.3 3.6 3 1 0 3 3 3 2 SlyX DivIC PF04977.15 KFP21776.1 - 0.0056 16.4 19.6 0.55 10.0 0.8 3.8 3 1 0 3 3 3 2 Septum formation initiator SOGA PF11365.8 KFP21776.1 - 0.01 17.0 20.6 0.012 16.7 9.2 3.0 3 1 0 3 3 2 0 Protein SOGA YabA PF06156.13 KFP21776.1 - 0.013 16.1 20.7 0.12 13.0 2.2 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 KFP21776.1 - 0.023 14.8 0.4 0.023 14.8 0.4 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF664 PF04978.12 KFP21776.1 - 0.12 12.8 0.2 0.35 11.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF664) Seryl_tRNA_N PF02403.22 KFP21776.1 - 0.14 12.4 23.0 0.16 12.2 4.4 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 KFP21776.1 - 0.23 11.0 7.3 0.07 12.6 3.8 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 KFP21776.1 - 0.5 10.6 18.0 2.9 8.1 6.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Chibby PF14645.6 KFP21776.1 - 0.71 10.3 15.5 0.38 11.2 4.7 2.8 2 1 0 2 2 2 0 Chibby family ATG16 PF08614.11 KFP21776.1 - 0.86 9.8 25.6 4.4 7.5 0.8 3.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) CpxA_peri PF16527.5 KFP21776.1 - 2.7 8.4 12.0 2 8.8 2.9 2.7 1 1 2 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain HIP1_clath_bdg PF16515.5 KFP21776.1 - 2.8 8.6 19.8 1.9 9.1 1.6 3.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HisKA PF00512.25 KFP21776.1 - 4.2 7.5 6.3 0.98 9.5 0.4 2.6 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF4407 PF14362.6 KFP21776.1 - 5.3 6.3 13.7 44 3.3 13.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KFP21776.1 - 5.6 7.5 27.1 14 6.3 8.1 3.0 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF5595 PF18077.1 KFP21776.1 - 6.4 6.9 11.8 2.5 8.3 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF641 PF04859.12 KFP21776.1 - 7.6 6.9 21.0 33 4.8 4.9 3.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) eIF3_N PF09440.10 KFP21776.1 - 7.6 7.0 10.5 0.93 9.9 2.1 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain GIT_CC PF16559.5 KFP21776.1 - 8.4 6.3 10.0 5 7.1 0.7 3.5 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor HEAT PF02985.22 KFP21777.1 - 2.1e-10 39.9 0.3 0.023 14.9 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KFP21777.1 - 2.2e-05 24.8 0.0 0.011 16.2 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KFP21777.1 - 0.00075 19.9 0.8 0.45 11.1 0.0 4.6 4 1 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 KFP21777.1 - 0.014 15.5 0.0 0.31 11.1 0.0 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TspO_MBR PF03073.15 KFP21777.1 - 0.022 14.8 0.3 0.044 13.8 0.3 1.4 1 0 0 1 1 1 0 TspO/MBR family Peptidase_M54 PF07998.11 KFP21778.1 - 0.00036 20.6 3.3 0.00089 19.3 3.3 1.6 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 KFP21778.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF4241 PF14025.6 KFP21778.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) G-alpha PF00503.20 KFP21779.1 - 1.3e-75 254.8 2.2 1.4e-75 254.6 2.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP21779.1 - 2.6e-10 40.0 0.7 6.8e-10 38.7 0.7 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP21779.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CARD PF00619.21 KFP21780.1 - 7e-22 77.3 0.0 2.7e-21 75.4 0.0 2.1 1 0 0 1 1 1 1 Caspase recruitment domain PDZ PF00595.24 KFP21780.1 - 2.8e-06 27.6 0.0 6.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Guanylate_kin PF00625.21 KFP21780.1 - 3.5e-05 23.6 6.6 4.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Guanylate kinase PDZ_6 PF17820.1 KFP21780.1 - 0.0007 19.4 0.0 0.0025 17.6 0.0 2.0 1 0 0 1 1 1 1 PDZ domain fn3 PF00041.21 KFP21781.1 - 4e-161 523.8 41.8 3e-15 56.3 0.4 14.0 13 1 0 13 13 13 13 Fibronectin type III domain Ig_3 PF13927.6 KFP21781.1 - 3.4e-73 242.2 0.3 2.7e-14 53.5 0.0 7.2 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP21781.1 - 2.9e-67 222.8 0.0 4.5e-16 58.7 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP21781.1 - 3.1e-50 168.4 0.1 5.3e-09 36.3 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KFP21781.1 - 3e-38 129.9 0.0 6.3e-09 35.9 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP21781.1 - 2.5e-26 92.1 24.0 0.00048 20.7 0.2 13.2 12 2 0 12 12 12 7 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFP21781.1 - 3.2e-15 56.2 13.7 0.039 14.1 0.1 11.3 8 5 3 11 11 11 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP21781.1 - 1.1e-08 34.5 0.1 0.24 11.0 0.0 6.1 7 0 0 7 7 7 2 Immunoglobulin domain Ig_5 PF16681.5 KFP21781.1 - 4.3e-08 33.4 0.0 0.18 12.2 0.0 6.2 6 1 0 6 6 6 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KFP21781.1 - 1.3e-07 31.5 0.3 0.41 10.7 0.0 5.3 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFP21781.1 - 8.1e-07 28.9 5.0 0.057 13.3 0.0 7.1 7 0 0 7 7 7 1 Tissue factor C1-set PF07654.15 KFP21781.1 - 1.6e-06 28.4 0.0 1.2 9.6 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin C1-set domain DUF2369 PF10179.9 KFP21781.1 - 0.0019 18.5 2.6 3.9 7.9 0.0 6.7 9 0 0 9 9 8 1 Uncharacterised conserved protein (DUF2369) GPI-anchored PF10342.9 KFP21781.1 - 0.0061 17.3 5.9 0.89 10.4 0.0 6.2 7 1 1 8 8 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C2-set PF05790.15 KFP21781.1 - 0.059 13.5 0.0 8.9 6.6 0.0 3.8 3 0 0 3 3 3 0 Immunoglobulin C2-set domain p450 PF00067.22 KFP21782.1 - 1.4e-110 370.2 0.2 1.6e-110 370.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFP21783.1 - 6.3e-128 427.4 0.1 7.1e-128 427.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Forkhead PF00250.18 KFP21784.1 - 2.8e-41 139.7 0.2 4.5e-41 139.0 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain SPG48 PF14764.6 KFP21785.1 - 5e-45 152.8 10.7 9.6e-45 151.9 3.5 3.6 4 0 0 4 4 4 1 AP-5 complex subunit, vesicle trafficking FANCF PF11107.8 KFP21785.1 - 0.41 9.8 2.7 0.42 9.8 1.4 1.7 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) DIL PF01843.19 KFP21786.1 - 8.5e-23 80.6 1.4 1.7e-22 79.6 1.4 1.5 1 0 0 1 1 1 1 DIL domain RA PF00788.23 KFP21786.1 - 2.2e-16 60.3 0.0 4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KFP21786.1 - 2.4e-10 40.6 0.0 4.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP21786.1 - 2.6e-10 40.0 0.0 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP21786.1 - 0.00071 19.9 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain HlyIII PF03006.20 KFP21787.1 - 2.3e-18 66.8 19.0 2.9e-18 66.4 19.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF998 PF06197.13 KFP21787.1 - 0.34 10.5 13.6 0.44 10.1 4.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF998) WD40 PF00400.32 KFP21788.1 - 3.6e-05 24.5 0.0 4 8.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21788.1 - 0.0015 18.7 0.0 0.17 12.2 0.0 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP21788.1 - 0.063 12.2 0.2 5.6 5.8 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KFP21788.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Nucleoside_tran PF01733.18 KFP21789.1 - 5e-50 170.6 3.5 5e-50 170.6 3.5 2.0 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KFP21789.1 - 0.016 14.2 26.4 0.013 14.4 9.5 2.8 1 1 0 2 2 2 0 Major Facilitator Superfamily F-box PF00646.33 KFP21790.1 - 6.6e-07 29.1 1.6 6.6e-07 29.1 1.6 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFP21790.1 - 1.9e-06 27.6 1.3 1.9e-06 27.6 1.3 2.5 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KFP21790.1 - 0.00026 21.3 17.3 0.024 15.1 0.4 6.0 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFP21790.1 - 0.0046 16.9 15.0 3.2 8.0 0.4 6.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KFP21790.1 - 4 7.3 14.3 3.2 7.6 0.5 5.3 6 1 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 KFP21790.1 - 4.8 8.1 16.9 18 6.4 0.6 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat Actin PF00022.19 KFP21791.1 - 1.3e-151 504.9 0.0 4.1e-151 503.2 0.0 1.6 1 1 0 1 1 1 1 Actin DUF226 PF02890.14 KFP21792.1 - 0.048 13.7 1.1 0.094 12.7 1.1 1.4 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Arm PF00514.23 KFP21793.1 - 2.2e-77 253.0 15.6 1.5e-11 43.9 0.1 8.9 9 1 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFP21793.1 - 1.1e-22 80.3 4.3 2.2e-22 79.3 4.3 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KFP21793.1 - 5.2e-21 74.7 3.2 1.2e-06 28.8 0.0 6.1 3 1 4 7 7 7 6 HEAT-like repeat Arm_3 PF16186.5 KFP21793.1 - 5.4e-19 67.5 1.4 8.1e-19 66.9 0.3 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KFP21793.1 - 9.2e-14 51.6 0.9 0.0014 19.0 0.0 6.0 3 2 4 7 7 7 4 HEAT repeats HEAT PF02985.22 KFP21793.1 - 4.3e-10 39.0 0.1 0.076 13.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat V-ATPase_H_C PF11698.8 KFP21793.1 - 7.1e-06 26.1 1.5 0.45 10.6 0.1 3.9 3 1 1 4 4 4 2 V-ATPase subunit H WD40 PF00400.32 KFP21794.1 - 1.5e-12 47.8 15.8 0.00015 22.5 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21794.1 - 2.5e-11 43.7 0.7 0.026 14.8 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LytB_WW PF18342.1 KFP21794.1 - 0.057 13.6 1.1 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain PP28 PF10252.9 KFP21795.1 - 3.1e-30 104.5 16.0 3.1e-30 104.5 16.0 2.5 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 RPN2_C PF18004.1 KFP21795.1 - 0.0039 17.1 7.7 0.0039 17.1 7.7 2.3 1 1 1 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PACT_coil_coil PF10495.9 KFP21795.1 - 0.83 10.3 7.8 0.15 12.6 3.6 2.0 2 1 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Nop53 PF07767.11 KFP21795.1 - 4.6 6.5 34.1 5.5 6.3 34.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) G10 PF01125.17 KFP21796.1 - 3.5e-67 224.7 5.2 3.8e-67 224.6 5.2 1.0 1 0 0 1 1 1 1 G10 protein PPR_2 PF13041.6 KFP21797.1 - 1.9e-45 152.9 3.4 1.3e-14 54.1 0.0 9.0 5 3 4 9 9 9 9 PPR repeat family PPR_3 PF13812.6 KFP21797.1 - 4.1e-34 116.4 0.3 1.4e-07 31.5 0.0 6.4 6 0 0 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 KFP21797.1 - 5.7e-18 63.8 12.3 8.2e-07 28.9 0.1 8.6 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KFP21797.1 - 4.5e-17 62.1 0.0 6e-11 42.1 0.1 4.3 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFP21797.1 - 1.3e-12 47.2 6.5 0.00041 20.0 0.0 7.8 9 0 0 9 9 9 3 PPR repeat MNE1 PF13762.6 KFP21797.1 - 0.017 15.1 0.9 0.69 9.9 0.1 3.7 2 2 2 4 4 4 0 Mitochondrial splicing apparatus component IRK_C PF17655.1 KFP21798.1 - 2.1e-71 239.1 0.0 2.8e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP21798.1 - 5.9e-66 220.6 1.4 8.1e-66 220.2 1.4 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFP21798.1 - 1.9e-24 85.5 0.2 3.3e-24 84.8 0.2 1.4 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFP21798.1 - 0.034 14.1 6.5 0.096 12.7 6.5 1.8 1 1 0 1 1 1 0 Ion channel Pkinase PF00069.25 KFP21800.1 - 2.5e-56 191.0 0.0 3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21800.1 - 1.3e-38 132.8 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21800.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP21800.1 - 0.0016 17.4 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP21800.1 - 0.0035 16.5 0.2 0.0054 15.8 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFP21800.1 - 0.009 14.8 0.1 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP21800.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP21800.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4344 PF14247.6 KFP21800.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase DHR-2 PF06920.13 KFP21800.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Dock homology region 2 RIO1 PF01163.22 KFP21800.1 - 0.097 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Acetyltransf_CG PF14542.6 KFP21801.1 - 1.4e-22 79.6 0.2 1.7e-22 79.3 0.2 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KFP21801.1 - 0.0026 18.0 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFP21801.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3222 PF11519.8 KFP21801.1 - 0.074 13.3 0.0 0.099 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3222) Acetyltransf_7 PF13508.7 KFP21801.1 - 0.079 13.4 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_morph_reg PF14972.6 KFP21802.1 - 8.9e-78 259.5 0.8 1e-77 259.3 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator GPI PF06560.11 KFP21802.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) adh_short PF00106.25 KFP21803.1 - 2.2e-51 174.1 0.3 3e-51 173.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP21803.1 - 2.8e-36 125.2 0.7 3.7e-36 124.8 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP21803.1 - 5.7e-12 45.9 0.1 9.9e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFP21803.1 - 7.5e-06 25.5 0.0 4.1e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KFP21803.1 - 0.00034 19.8 0.6 0.00044 19.5 0.1 1.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KFP21803.1 - 0.00058 20.1 0.1 0.0016 18.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 KFP21803.1 - 0.029 13.7 0.8 0.61 9.4 0.0 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KFP21803.1 - 0.045 14.0 0.2 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HEPN PF05168.14 KFP21803.1 - 0.064 13.4 0.0 0.59 10.3 0.0 2.3 3 0 0 3 3 3 0 HEPN domain Shikimate_DH PF01488.20 KFP21803.1 - 0.079 13.0 0.6 0.32 11.1 0.1 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UCH PF00443.29 KFP21804.1 - 9.5e-58 195.7 0.1 1.2e-57 195.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP21804.1 - 8.6e-25 88.0 2.8 3.5e-24 86.0 2.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFP21804.1 - 6.3e-14 52.0 10.7 6.3e-14 52.0 10.7 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KFP21804.1 - 3.5e-05 23.4 3.3 0.011 15.3 0.1 3.3 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ISG65-75 PF11727.8 KFP21804.1 - 0.3 10.3 4.6 0.055 12.7 0.7 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein zf-RING_13 PF17977.1 KFP21804.1 - 0.92 9.7 7.6 4.1 7.6 7.6 2.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DSPc PF00782.20 KFP21806.1 - 2e-38 131.2 0.0 2.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP21806.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Homeodomain PF00046.29 KFP21807.1 - 2.2e-19 69.0 3.5 2.7e-19 68.8 3.5 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP21807.1 - 0.00017 21.4 2.9 0.00029 20.7 2.9 1.6 1 1 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.11 KFP21807.1 - 0.026 14.7 0.1 0.039 14.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1510) HTH_23 PF13384.6 KFP21807.1 - 0.049 13.4 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homez PF11569.8 KFP21807.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Glyco_hydro_47 PF01532.20 KFP21808.1 - 2.3e-105 353.2 0.0 4.1e-105 352.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2063 PF09836.9 KFP21808.1 - 0.11 12.7 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain Arf PF00025.21 KFP21809.1 - 1.1e-39 135.7 0.1 1.3e-39 135.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFP21809.1 - 5.6e-15 55.3 0.0 6.2e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP21809.1 - 4.8e-11 42.9 0.0 7.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP21809.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFP21809.1 - 1.5e-05 24.4 0.1 2e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KFP21809.1 - 0.005 16.3 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFP21809.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Hairy_orange PF07527.13 KFP21810.1 - 4.4e-11 42.8 0.3 8.9e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 Hairy Orange Hairy_orange PF07527.13 KFP21811.1 - 5e-11 42.6 0.3 1.1e-10 41.6 0.3 1.6 1 0 0 1 1 1 1 Hairy Orange PAS_6 PF08348.11 KFP21811.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 YheO-like PAS domain Ins145_P3_rec PF08709.11 KFP21812.1 - 1.8e-95 318.2 0.1 1.9e-94 314.8 0.0 2.6 3 0 0 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 KFP21812.1 - 7.7e-72 241.0 26.1 1.1e-61 207.9 0.5 5.3 6 0 0 6 6 6 2 RIH domain MIR PF02815.19 KFP21812.1 - 4.1e-71 238.7 0.1 8e-68 228.0 0.0 2.6 2 0 0 2 2 2 2 MIR domain RIH_assoc PF08454.11 KFP21812.1 - 3.9e-31 106.9 6.9 3.9e-31 106.9 6.9 6.3 6 2 0 6 6 6 2 RyR and IP3R Homology associated Ion_trans PF00520.31 KFP21812.1 - 2.7e-20 72.6 6.5 2.7e-20 72.6 6.5 2.5 2 1 0 2 2 2 1 Ion transport protein Plk4_PB2 PF18409.1 KFP21812.1 - 0.2 12.4 2.3 0.81 10.4 0.4 3.1 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Sigma_reg_N PF13800.6 KFP21812.1 - 4.4 7.7 7.9 1.8 8.9 0.1 3.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal FGE-sulfatase PF03781.16 KFP21813.1 - 1.4e-88 296.9 7.6 1.6e-88 296.7 7.6 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 SET PF00856.28 KFP21814.1 - 3.7e-21 76.2 0.1 1.1e-19 71.4 0.1 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KFP21814.1 - 3.9e-06 27.5 11.9 3.9e-06 27.5 11.9 1.9 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KFP21814.1 - 0.001 19.1 4.1 0.001 19.1 4.1 2.4 2 0 0 2 2 2 1 AWS domain LRR_8 PF13855.6 KFP21815.1 - 3.1e-51 171.0 68.4 1.9e-13 50.0 3.3 6.1 1 1 6 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 KFP21815.1 - 7.1e-25 87.4 1.0 1.1e-11 44.8 3.1 4.0 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KFP21815.1 - 2e-24 85.3 48.1 3.3e-06 27.3 1.7 8.7 4 1 2 9 9 9 6 Leucine Rich repeats (2 copies) I-set PF07679.16 KFP21815.1 - 5.9e-16 58.3 0.1 3.8e-15 55.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_9 PF14580.6 KFP21815.1 - 4.3e-13 49.1 25.0 0.00026 20.6 3.5 4.4 1 1 3 4 4 4 4 Leucine-rich repeat Ig_3 PF13927.6 KFP21815.1 - 7.5e-13 48.9 0.1 2.6e-12 47.2 0.0 2.0 2 0 0 2 2 1 1 Immunoglobulin domain ig PF00047.25 KFP21815.1 - 7.5e-08 32.5 0.1 8.2e-07 29.1 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFP21815.1 - 7.1e-07 29.5 0.0 5.5e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain LRRCT PF01463.24 KFP21815.1 - 6.3e-05 23.2 0.1 0.00016 21.9 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain V-set PF07686.17 KFP21815.1 - 7e-05 23.0 0.2 0.0016 18.6 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_1 PF00560.33 KFP21815.1 - 0.00013 22.1 27.2 0.078 13.6 0.2 9.4 10 0 0 10 10 9 1 Leucine Rich Repeat LRRNT PF01462.18 KFP21815.1 - 0.00024 20.6 1.0 0.00024 20.6 1.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.21 KFP21815.1 - 0.0016 18.8 1.5 0.0035 17.7 1.5 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP21815.1 - 0.0029 18.1 1.9 0.011 16.3 1.9 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 KFP21815.1 - 0.012 15.1 0.0 0.097 12.3 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain LRR_6 PF13516.6 KFP21815.1 - 0.027 14.5 16.0 15 6.0 0.1 6.8 4 1 1 5 5 5 0 Leucine Rich repeat Ig_5 PF16681.5 KFP21815.1 - 0.062 13.7 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LON_substr_bdg PF02190.16 KFP21816.1 - 3.5e-24 85.8 0.0 4.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 KFP21816.1 - 2.8e-11 43.6 0.2 5.4e-11 42.6 0.2 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Baculo_ME53 PF06061.11 KFP21816.1 - 0.15 11.3 2.3 0.24 10.6 2.3 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 PolyA_pol PF01743.20 KFP21817.1 - 5.9e-33 114.0 0.3 9.6e-33 113.3 0.3 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFP21817.1 - 4.9e-13 48.6 0.4 3.8e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A PRC PF05239.16 KFP21817.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 PRC-barrel domain IL6Ra-bind PF09240.10 KFP21818.1 - 1.2e-22 80.1 0.5 3.3e-22 78.7 0.1 1.9 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.17 KFP21818.1 - 2.5e-06 27.3 6.8 0.0075 16.1 0.4 3.2 3 0 0 3 3 3 2 Tissue factor Il13Ra_Ig PF18001.1 KFP21818.1 - 0.0028 17.7 0.0 0.077 13.1 0.0 2.5 2 0 0 2 2 2 1 Interleukin-13 receptor subunit alpha Ig-like domain fn3 PF00041.21 KFP21818.1 - 0.003 17.9 2.9 0.81 10.1 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Ig_3 PF13927.6 KFP21819.1 - 2.2e-74 246.0 9.8 1.2e-14 54.6 0.0 7.4 8 0 0 8 8 7 6 Immunoglobulin domain I-set PF07679.16 KFP21819.1 - 2.3e-69 229.5 0.0 2e-14 53.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain ig PF00047.25 KFP21819.1 - 3.6e-55 184.1 4.1 3.4e-11 43.2 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain Ig_2 PF13895.6 KFP21819.1 - 4.4e-49 164.7 0.0 6.6e-08 32.8 0.0 6.8 5 1 1 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 KFP21819.1 - 1.3e-41 140.8 12.8 9.1e-15 54.8 0.2 4.5 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KFP21819.1 - 1e-31 109.3 8.7 2.7e-05 24.3 0.2 10.9 7 4 1 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP21819.1 - 1.1e-17 63.4 0.0 0.099 12.2 0.0 6.6 6 0 0 6 6 6 5 Immunoglobulin domain Ig_5 PF16681.5 KFP21819.1 - 6.3e-12 45.7 0.0 0.013 15.9 0.0 7.2 7 0 0 7 7 7 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KFP21819.1 - 1.5e-10 41.0 0.0 0.3 11.1 0.0 5.7 5 0 0 5 5 5 3 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP21819.1 - 6e-10 39.1 0.1 3.5 7.8 0.0 6.3 6 0 0 6 6 6 3 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP21819.1 - 1.1e-07 32.0 0.1 1 9.7 0.0 5.7 6 1 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP21819.1 - 0.00012 22.1 0.2 0.39 10.8 0.0 3.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KFP21819.1 - 0.00016 21.6 0.9 14 5.6 0.1 4.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain fn3_2 PF16893.5 KFP21819.1 - 0.00023 21.3 0.2 1.2 9.4 0.0 3.8 4 0 0 4 4 4 2 Fibronectin type III domain Adeno_E3_CR1 PF02440.15 KFP21819.1 - 0.00046 19.9 0.3 2.3 8.1 0.0 4.4 4 0 0 4 4 4 1 Adenovirus E3 region protein CR1 Tissue_fac PF01108.17 KFP21819.1 - 0.00068 19.5 1.4 0.39 10.6 0.2 3.0 3 0 0 3 3 3 2 Tissue factor fn3_4 PF16794.5 KFP21819.1 - 0.0042 17.0 0.1 5.4 7.0 0.0 3.2 3 0 0 3 3 3 1 Fibronectin-III type domain Pur_ac_phosph_N PF16656.5 KFP21819.1 - 0.04 14.5 8.6 0.16 12.6 0.0 3.9 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Ig_3 PF13927.6 KFP21820.1 - 5.8e-79 260.7 8.0 1e-14 54.9 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KFP21820.1 - 6.7e-78 256.9 0.0 2.1e-14 53.3 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP21820.1 - 1.1e-53 179.5 7.2 5.7e-09 36.2 0.0 7.4 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KFP21820.1 - 1.1e-53 179.4 4.0 3.1e-12 46.5 0.0 7.2 7 1 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 KFP21820.1 - 1.4e-35 121.5 17.6 5.7e-13 49.0 1.8 5.2 5 0 0 5 5 5 4 Fibronectin type III domain V-set PF07686.17 KFP21820.1 - 7.8e-31 106.5 11.3 0.002 18.3 0.0 11.6 7 5 1 8 8 8 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP21820.1 - 7.3e-14 51.1 0.0 0.056 13.0 0.0 6.4 6 0 0 6 6 6 4 Immunoglobulin domain Ig_5 PF16681.5 KFP21820.1 - 5.7e-12 45.9 0.1 0.24 11.8 0.0 7.0 7 0 0 7 7 7 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KFP21820.1 - 1.2e-08 34.9 0.0 3.9 7.6 0.0 6.0 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP21820.1 - 3.4e-08 33.6 0.1 1.8 8.9 0.0 6.1 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP21820.1 - 3.6e-08 33.4 0.3 0.43 10.7 0.0 5.2 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.17 KFP21820.1 - 0.00013 21.8 1.5 0.013 15.4 0.1 3.1 3 0 0 3 3 2 1 Tissue factor Pur_ac_phosph_N PF16656.5 KFP21820.1 - 0.00033 21.2 3.2 0.12 13.0 0.3 3.3 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP21820.1 - 0.0014 18.9 0.1 6 7.2 0.0 3.6 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III fn3_4 PF16794.5 KFP21820.1 - 0.0056 16.6 0.9 0.25 11.3 0.2 3.2 3 0 0 3 3 3 1 Fibronectin-III type domain C2-set PF05790.15 KFP21820.1 - 0.0072 16.5 0.0 37 4.6 0.0 5.1 6 0 0 6 6 5 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.11 KFP21820.1 - 0.0079 16.2 6.5 12 5.9 0.0 5.1 4 1 1 5 5 5 0 CD47 immunoglobulin-like domain Adeno_E3_CR1 PF02440.15 KFP21820.1 - 0.09 12.6 0.5 43 4.0 0.0 4.1 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Ig_3 PF13927.6 KFP21821.1 - 4.3e-71 235.5 2.2 1.9e-12 47.6 0.0 7.2 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KFP21821.1 - 1.7e-68 226.7 0.6 1.3e-12 47.6 0.0 7.1 8 0 0 8 8 6 6 Immunoglobulin I-set domain fn3 PF00041.21 KFP21821.1 - 6.8e-54 180.2 6.9 7.2e-13 48.7 0.0 5.7 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.6 KFP21821.1 - 5.8e-47 157.9 0.4 7.6e-09 35.8 0.0 6.8 7 0 0 7 7 6 6 Immunoglobulin domain ig PF00047.25 KFP21821.1 - 3.8e-43 145.6 1.1 1.7e-07 31.3 0.0 7.1 7 0 0 7 7 7 6 Immunoglobulin domain Bravo_FIGEY PF13882.6 KFP21821.1 - 1.1e-29 103.6 3.9 2.3e-29 102.6 3.9 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.17 KFP21821.1 - 1.7e-20 73.2 4.3 0.00083 19.5 0.0 8.9 6 4 2 8 8 8 4 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP21821.1 - 7.8e-11 42.1 0.0 0.52 10.6 0.0 5.8 6 0 0 6 6 6 3 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP21821.1 - 8.4e-09 35.4 0.8 0.16 12.1 0.0 6.2 6 1 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP21821.1 - 4.8e-08 32.4 0.0 0.0044 16.5 0.0 4.4 5 0 0 5 5 5 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP21821.1 - 0.00015 22.2 2.6 15 6.2 0.2 4.9 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KFP21821.1 - 0.00056 19.9 0.0 20 5.4 0.0 5.0 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KFP21821.1 - 0.00058 20.0 0.8 8.5 6.6 0.0 4.4 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 C2-set PF05790.15 KFP21821.1 - 0.00079 19.6 0.1 16 5.7 0.0 4.3 4 0 0 4 4 4 0 Immunoglobulin C2-set domain fn3_2 PF16893.5 KFP21821.1 - 0.0021 18.2 0.0 0.025 14.7 0.0 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Ig_C17orf99 PF17736.1 KFP21821.1 - 0.007 16.4 0.5 42 4.3 0.0 4.8 6 0 0 6 6 5 0 C17orf99 Ig domain I-set PF07679.16 KFP21822.1 - 2.6e-70 232.5 0.0 9.5e-17 60.9 0.0 6.5 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21822.1 - 2.5e-65 217.0 7.5 1.3e-12 48.1 0.0 6.7 8 0 0 8 8 7 5 Immunoglobulin domain fn3 PF00041.21 KFP21822.1 - 1.8e-45 153.1 18.3 3.5e-15 56.1 1.9 4.4 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.25 KFP21822.1 - 1.2e-44 150.4 0.6 1.3e-09 38.1 0.0 6.7 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 KFP21822.1 - 3e-44 149.3 0.2 7.5e-10 39.0 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFP21822.1 - 7.9e-29 100.0 11.6 0.0017 18.5 0.5 10.4 7 4 1 8 8 8 6 Immunoglobulin V-set domain Ig_5 PF16681.5 KFP21822.1 - 8e-12 45.4 0.0 0.083 13.3 0.0 6.0 6 0 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KFP21822.1 - 3.4e-10 39.3 0.0 0.67 9.6 0.0 5.4 5 0 0 5 5 5 3 Immunoglobulin domain Tissue_fac PF01108.17 KFP21822.1 - 1.2e-06 28.3 2.0 0.00024 20.9 0.1 3.0 3 0 0 3 3 3 1 Tissue factor Izumo-Ig PF16706.5 KFP21822.1 - 1.3e-06 28.4 0.1 6.6 6.9 0.0 5.4 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KFP21822.1 - 0.00012 22.2 2.1 1.4 9.2 0.1 4.9 5 1 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 KFP21822.1 - 0.00037 20.5 6.5 2.2 8.4 0.0 5.2 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 KFP21822.1 - 0.0044 17.3 0.0 8 6.8 0.0 3.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KFP21822.1 - 0.0047 17.5 10.4 0.11 13.0 0.7 3.8 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFP21822.1 - 0.0077 16.2 0.0 13 5.9 0.0 4.5 6 0 0 6 6 4 0 C17orf99 Ig domain Egh16-like PF11327.8 KFP21822.1 - 0.014 15.8 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 0 Egh16-like virulence factor Big_4 PF07532.11 KFP21822.1 - 0.11 12.2 6.2 2.7 7.8 0.1 3.9 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 4) PDZ PF00595.24 KFP21823.1 - 6.5e-19 68.1 1.3 6.3e-14 52.1 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KFP21823.1 - 9.2e-15 54.2 0.9 4e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KFP21823.1 - 1.1e-06 28.9 0.2 6.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KFP21823.1 - 0.019 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain PPP4R2 PF09184.11 KFP21824.1 - 6e-77 259.1 11.8 6e-77 259.1 11.8 2.4 1 1 1 2 2 2 1 PPP4R2 Glyco_transf_8 PF01501.20 KFP21825.1 - 3.7e-11 43.1 0.0 6.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Toxin_16 PF07945.11 KFP21825.1 - 0.4 10.6 0.1 0.4 10.6 0.1 1.7 2 0 0 2 2 2 0 Janus-atracotoxin SHQ1 PF04925.15 KFP21826.1 - 5.7e-68 227.9 1.7 8.9e-68 227.3 1.7 1.3 1 0 0 1 1 1 1 SHQ1 protein DUF4158 PF13700.6 KFP21826.1 - 0.039 13.8 0.3 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) V_ATPase_I PF01496.19 KFP21826.1 - 0.06 11.3 1.6 0.091 10.7 1.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Coilin_N PF15862.5 KFP21826.1 - 0.098 12.5 1.7 0.23 11.2 1.7 1.7 1 0 0 1 1 1 0 Coilin N-terminus TLP-20 PF06088.11 KFP21826.1 - 0.12 12.2 2.0 0.39 10.6 2.0 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) YAF2_RYBP PF17219.3 KFP21827.1 - 1.4e-20 72.6 1.2 3.2e-20 71.4 1.2 1.7 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 KFP21827.1 - 1.8e-08 33.5 2.4 3.6e-08 32.6 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KFP21827.1 - 0.11 12.8 1.1 0.22 11.8 1.1 1.4 1 0 0 1 1 1 0 C1 domain SOG2 PF10428.9 KFP21827.1 - 4.1 6.5 21.1 5.9 6.0 21.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Prokineticin PF06607.11 KFP21828.1 - 1e-39 134.8 9.8 1.1e-39 134.6 9.8 1.0 1 0 0 1 1 1 1 Prokineticin MIT_LIKE_ACTX PF17556.2 KFP21828.1 - 0.0069 17.0 7.9 0.0091 16.6 7.9 1.2 1 0 0 1 1 1 1 MIT-like atracotoxin family 7tm_1 PF00001.21 KFP21829.1 - 7e-31 107.5 10.5 8.4e-31 107.2 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0114 PF03350.16 KFP21829.1 - 1.8 8.8 6.9 0.88 9.8 3.7 2.0 1 1 0 2 2 2 0 Uncharacterized protein family, UPF0114 IF4E PF01652.18 KFP21831.1 - 1.2e-37 129.2 0.0 1.3e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FOXP-CC PF16159.5 KFP21832.1 - 2.2e-34 117.9 5.3 2.2e-34 117.9 5.3 4.3 5 1 1 6 6 6 1 FOXP coiled-coil domain Forkhead PF00250.18 KFP21832.1 - 3.4e-28 97.7 0.1 7.7e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Zap1_zf2 PF18217.1 KFP21832.1 - 0.088 12.8 0.6 0.16 12.0 0.6 1.5 1 0 0 1 1 1 0 Zap1 zinc finger 2 Auxin_repressed PF05564.12 KFP21832.1 - 1.4 9.6 6.2 1.9 9.2 2.6 2.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein MDFI PF15316.6 KFP21833.1 - 2.1e-50 171.2 17.6 2.2e-50 171.0 17.6 1.0 1 0 0 1 1 1 1 MyoD family inhibitor adh_short_C2 PF13561.6 KFP21834.1 - 4.7e-62 209.6 1.1 7.1e-62 209.0 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP21834.1 - 8.3e-53 178.8 4.4 1.1e-52 178.3 1.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_3 PF01596.17 KFP21834.1 - 3e-33 114.8 0.0 4.8e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase KR PF08659.10 KFP21834.1 - 3.6e-10 40.0 1.4 5.4e-10 39.5 0.6 1.7 2 0 0 2 2 2 1 KR domain Methyltransf_24 PF13578.6 KFP21834.1 - 0.0016 19.4 0.0 0.0036 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KFP21834.1 - 0.0036 16.4 0.9 0.66 8.9 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DHQ_synthase PF01761.20 KFP21835.1 - 2.7e-57 193.9 0.0 3.4e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KFP21835.1 - 1.3e-15 57.8 0.0 6.4e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KFP21835.1 - 1.9e-05 23.7 0.0 3.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SwrA PF17423.2 KFP21835.1 - 0.042 13.8 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Swarming motility protein MITF_TFEB_C_3_N PF15951.5 KFP21836.1 - 2.4e-50 171.1 23.2 2.4e-50 171.1 23.2 2.8 2 1 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus DUF3371 PF11851.8 KFP21836.1 - 2.7e-37 128.8 0.9 2.7e-37 128.8 0.9 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3371) HLH PF00010.26 KFP21836.1 - 1.9e-16 59.8 0.6 1.9e-16 59.8 0.6 2.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Ribophorin_I PF04597.14 KFP21836.1 - 0.12 11.5 5.9 0.24 10.6 5.9 1.4 1 0 0 1 1 1 0 Ribophorin I TFIIA PF03153.13 KFP21836.1 - 6 6.8 19.0 12 5.7 18.9 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3338 PF11819.8 KFP21837.1 - 8.1e-54 181.3 8.2 8.1e-54 181.3 8.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_C PF09380.10 KFP21837.1 - 5.5e-23 81.2 0.5 1.9e-22 79.5 0.5 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KFP21837.1 - 1.6e-11 43.9 0.5 4.2e-11 42.6 0.5 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KFP21837.1 - 2.1e-11 44.3 0.7 4.8e-10 39.9 0.0 2.8 2 0 0 2 2 2 1 FERM central domain T2SSG PF08334.11 KFP21837.1 - 0.071 13.2 0.1 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G zf-C4pol PF14260.6 KFP21837.1 - 4 8.0 4.7 1.3 9.5 0.5 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Med30 PF11315.8 KFP21837.1 - 9.6 6.4 9.5 12 6.1 3.8 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 PRA1 PF03208.19 KFP21838.1 - 9.2e-15 54.5 3.6 1.1e-14 54.3 3.6 1.0 1 0 0 1 1 1 1 PRA1 family protein Halogen_Hydrol PF10112.9 KFP21838.1 - 0.02 14.9 0.3 0.038 14.0 0.1 1.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PsbX PF06596.11 KFP21838.1 - 0.069 13.2 0.5 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) LapA_dom PF06305.11 KFP21838.1 - 0.13 12.1 2.1 9.6 6.1 0.2 2.5 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3487 PF11990.8 KFP21838.1 - 0.63 10.0 5.0 0.69 9.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF3413 PF11893.8 KFP21838.1 - 7.8 5.6 9.2 28 3.8 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) ThiF PF00899.21 KFP21839.1 - 4.6e-68 229.2 0.0 6.8e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFP21839.1 - 1e-24 86.4 0.3 2e-24 85.5 0.3 1.5 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KFP21839.1 - 0.00079 20.0 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 KFP21839.1 - 0.00079 19.5 0.0 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFP21839.1 - 0.087 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TMF_TATA_bd PF12325.8 KFP21840.1 - 1.2e-32 112.5 11.6 1.2e-32 112.5 11.6 8.0 2 1 4 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFP21840.1 - 7.6e-20 70.7 25.9 7.6e-20 70.7 25.9 10.9 7 3 3 11 11 11 5 TATA element modulatory factor 1 DNA binding DUF563 PF04577.14 KFP21841.1 - 6.1e-28 98.4 0.4 1.1e-27 97.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TAFA PF12020.8 KFP21842.1 - 7.1e-48 161.0 11.8 8.1e-48 160.8 11.8 1.0 1 0 0 1 1 1 1 TAFA family TAFA PF12020.8 KFP21843.1 - 5.4e-45 151.8 12.6 6e-45 151.6 12.6 1.0 1 0 0 1 1 1 1 TAFA family EGF PF00008.27 KFP21843.1 - 6.1 7.2 14.3 0.69 10.3 0.7 3.4 2 1 0 2 2 2 0 EGF-like domain PDEase_I PF00233.19 KFP21844.1 - 1.1e-27 97.3 3.0 1.2e-27 97.2 3.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Helicase_RecD PF05127.14 KFP21844.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Helicase HRG PF16954.5 KFP21845.1 - 8.4e-22 77.3 13.1 1.7e-21 76.3 5.8 2.2 2 0 0 2 2 2 2 Haem-transporter, endosomal/lysosomal, haem-responsive gene 7tm_1 PF00001.21 KFP21845.1 - 0.31 10.3 7.7 0.37 10.1 7.7 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HLH PF00010.26 KFP21846.1 - 2.6e-16 59.3 0.4 4.2e-16 58.6 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 KFP21846.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF773 PF05600.12 KFP21846.1 - 0.019 13.7 0.1 0.023 13.5 0.1 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF390 PF04094.14 KFP21846.1 - 0.057 11.7 0.4 0.069 11.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Hist_deacetyl PF00850.19 KFP21847.1 - 2.5e-81 273.5 0.0 9.2e-81 271.7 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain PDEase_I PF00233.19 KFP21848.1 - 2.2e-81 273.1 8.7 3.1e-81 272.6 8.1 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KFP21848.1 - 3.9e-31 106.7 0.1 1.1e-30 105.2 0.1 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DARPP-32 PF05395.12 KFP21849.1 - 1.9e-19 70.5 5.9 1.4e-18 67.6 5.9 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 UQ_con PF00179.26 KFP21850.1 - 8.2e-47 158.4 0.0 1.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFP21850.1 - 0.009 15.7 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFP21850.1 - 0.0094 16.2 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFP21850.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF4663 PF15668.5 KFP21850.1 - 2.4 7.1 5.2 3.4 6.6 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) MA3 PF02847.17 KFP21851.1 - 1.5e-24 86.2 1.7 3.2e-24 85.1 1.7 1.6 1 0 0 1 1 1 1 MA3 domain SSP160 PF06933.11 KFP21851.1 - 1.7 6.7 12.2 2.6 6.1 12.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-met PF12874.7 KFP21852.1 - 9e-29 99.0 25.2 1.2e-07 31.8 1.9 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP21852.1 - 2.3e-22 78.7 20.7 3e-06 27.4 3.0 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP21852.1 - 7.9e-10 39.0 9.2 0.15 12.4 0.4 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 KFP21852.1 - 2.2e-09 36.9 12.2 0.016 15.0 0.0 4.3 4 0 0 4 4 4 4 U1 zinc finger AKAP95 PF04988.12 KFP21852.1 - 1.3e-06 28.8 6.9 0.19 11.9 0.1 4.2 4 0 0 4 4 4 2 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 KFP21852.1 - 0.0082 16.2 13.3 0.19 11.8 0.8 4.3 4 0 0 4 4 4 1 DBF zinc finger DUF3449 PF11931.8 KFP21852.1 - 0.0098 15.7 1.1 8.7 6.1 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2 PF00096.26 KFP21852.1 - 0.017 15.5 12.4 5.2 7.7 1.4 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type UPF0728 PF15092.6 KFP21852.1 - 0.094 12.6 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 zinc_ribbon_15 PF17032.5 KFP21852.1 - 0.17 12.6 7.5 5.9 7.7 0.2 3.5 3 1 0 3 3 3 0 zinc-ribbon family zf-C2H2_9 PF16293.5 KFP21852.1 - 0.25 11.2 8.4 29 4.6 0.3 4.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 KFP21852.1 - 0.26 12.2 9.9 11 7.2 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-piccolo PF05715.13 KFP21852.1 - 0.45 10.7 6.7 21 5.3 0.1 4.0 4 0 0 4 4 4 0 Piccolo Zn-finger C1_1 PF00130.22 KFP21852.1 - 0.68 9.9 3.7 21 5.1 0.0 3.7 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.21 KFP21852.1 - 1 9.6 5.2 8.5 6.7 0.0 3.4 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 KFP21852.1 - 1.9 8.7 4.5 8.4 6.7 0.1 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain Actin_micro PF17003.5 KFP21852.1 - 1.9 7.6 13.9 2.2 7.4 0.2 3.6 3 1 0 3 3 3 0 Putative actin-like family zf_C2H2_ZHX PF18387.1 KFP21852.1 - 2 8.1 9.9 1.3 8.7 0.4 2.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain CRAL_TRIO_2 PF13716.6 KFP21853.1 - 1.1e-07 32.1 0.1 2.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.21 KFP21853.1 - 0.00015 22.2 24.6 0.0012 19.3 0.4 4.8 4 1 1 5 5 5 2 Spectrin repeat MatP PF06303.12 KFP21853.1 - 0.06 13.9 3.1 1 10.0 0.9 3.0 2 0 0 2 2 2 0 MatP N-terminal domain Spectrin PF00435.21 KFP21854.1 - 0.017 15.6 16.1 0.093 13.2 1.3 2.9 1 1 1 2 2 2 0 Spectrin repeat AAA_23 PF13476.6 KFP21854.1 - 8.7 6.8 12.5 2 8.9 7.4 2.0 2 0 0 2 2 2 0 AAA domain I-set PF07679.16 KFP21856.1 - 0 1445.1 39.4 5.4e-23 80.9 0.0 28.3 28 0 0 28 28 28 28 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21856.1 - 1.9e-263 851.9 11.3 1.2e-15 57.9 0.0 28.4 28 0 0 28 28 28 27 Immunoglobulin domain ig PF00047.25 KFP21856.1 - 2.3e-147 479.6 28.3 1.5e-11 44.3 0.1 26.7 27 0 0 27 27 26 24 Immunoglobulin domain Ig_2 PF13895.6 KFP21856.1 - 6.7e-141 458.9 22.9 2.2e-12 47.1 0.1 26.5 23 2 2 26 26 26 19 Immunoglobulin domain V-set PF07686.17 KFP21856.1 - 4.3e-49 165.2 48.2 0.029 14.5 0.1 33.4 26 12 0 26 26 26 12 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP21856.1 - 1.9e-37 127.2 1.4 0.043 13.9 0.0 17.7 19 0 0 19 19 18 9 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP21856.1 - 3.7e-19 68.9 17.0 0.041 14.2 0.0 17.8 20 0 0 20 20 19 3 Immunoglobulin C1-set domain Titin_Z PF09042.11 KFP21856.1 - 7.7e-19 67.4 15.3 2.5e-13 49.7 7.2 3.0 2 0 0 2 2 2 2 Titin Z Receptor_2B4 PF11465.8 KFP21856.1 - 2.7e-13 50.1 11.1 0.33 11.2 0.0 13.7 16 2 2 18 18 15 2 Natural killer cell receptor 2B4 Ig_5 PF16681.5 KFP21856.1 - 1.6e-11 44.5 17.9 0.29 11.6 0.0 13.7 13 0 0 13 13 13 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP21856.1 - 4.3e-10 39.7 18.6 0.064 13.5 0.1 13.8 15 0 0 15 15 15 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KFP21856.1 - 1.5e-08 34.6 16.9 0.58 10.3 0.2 12.2 15 0 0 15 15 13 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 KFP21856.1 - 5.6e-06 26.3 4.1 14 5.8 0.0 9.1 10 0 0 10 10 9 0 C17orf99 Ig domain PKD_3 PF16820.5 KFP21856.1 - 0.0017 18.1 1.0 0.47 10.2 0.0 5.3 5 0 0 5 5 5 1 PKD-like domain DUF4198 PF10670.9 KFP21856.1 - 0.0039 17.6 7.1 0.12 12.7 0.0 6.8 7 1 1 8 8 5 1 Domain of unknown function (DUF4198) V-set_CD47 PF08204.11 KFP21856.1 - 0.0072 16.3 11.2 0.3 11.1 0.1 7.6 9 0 0 9 9 8 1 CD47 immunoglobulin-like domain CRR7 PF12095.8 KFP21856.1 - 0.033 14.6 0.0 0.033 14.6 0.0 3.0 3 0 0 3 3 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Laminin_G_1 PF00054.23 KFP21856.1 - 0.067 13.4 0.0 6.4 7.0 0.0 4.0 3 0 0 3 3 3 0 Laminin G domain DUF11 PF01345.18 KFP21856.1 - 0.39 11.0 4.6 65 3.9 0.0 6.1 6 0 0 6 6 5 0 Domain of unknown function DUF11 I-set PF07679.16 KFP21857.1 - 5.6e-12 45.6 0.0 7.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21857.1 - 9.2e-07 29.4 0.0 1.5e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP21857.1 - 3.3e-05 24.0 0.0 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KFP21857.1 - 0.00023 20.7 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP21857.1 - 0.00034 20.9 0.0 0.00059 20.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP21857.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain V-set PF07686.17 KFP21857.1 - 0.0025 18.0 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain fn3 PF00041.21 KFP21858.1 - 1.1e-103 339.8 6.6 2.5e-20 72.6 0.1 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.16 KFP21858.1 - 6.4e-33 112.7 1.6 8.3e-15 54.6 0.1 4.2 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21858.1 - 1.1e-18 67.6 0.0 2.8e-08 34.2 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP21858.1 - 1.8e-17 63.7 8.2 0.0025 18.3 0.1 7.8 8 0 0 8 8 8 4 Purple acid Phosphatase, N-terminal domain ig PF00047.25 KFP21858.1 - 5.6e-12 45.7 0.0 2.7e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP21858.1 - 1.2e-09 38.4 0.0 0.00077 19.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Tissue_fac PF01108.17 KFP21858.1 - 1e-08 34.9 0.1 0.0087 15.9 0.0 5.3 5 0 0 5 5 5 2 Tissue factor SusE PF14292.6 KFP21858.1 - 3.9e-06 27.0 0.1 0.97 9.7 0.0 4.5 4 0 0 4 4 4 2 SusE outer membrane protein fn3_2 PF16893.5 KFP21858.1 - 2.6e-05 24.3 0.0 2.9 8.1 0.0 5.3 6 0 0 6 6 6 1 Fibronectin type III domain Lipocalin_7 PF14651.6 KFP21858.1 - 0.0026 17.7 0.0 1.4 8.9 0.0 3.5 4 0 0 4 4 4 1 Lipocalin / cytosolic fatty-acid binding protein family Reeler PF02014.16 KFP21858.1 - 0.0044 17.8 0.1 51 4.6 0.0 4.7 5 0 0 5 5 5 0 Reeler domain DUF2369 PF10179.9 KFP21858.1 - 0.044 14.2 0.0 56 4.2 0.0 4.2 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Herpes_gE PF02480.16 KFP21858.1 - 0.066 11.9 0.0 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Haem_degrading PF03928.14 KFP21858.1 - 0.12 12.4 0.1 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Haem-degrading I-set PF07679.16 KFP21859.1 - 8.4e-08 32.2 0.0 8.8e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21859.1 - 7.2e-06 26.5 0.0 7.3e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP21859.1 - 0.019 15.3 0.0 0.022 15.1 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.12 KFP21859.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFP21860.1 - 6e-07 29.4 0.0 6.5e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21860.1 - 2.4e-06 28.1 0.0 2.4e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP21860.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP21861.1 - 3.2e-07 30.3 0.0 3.3e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21861.1 - 2.4e-05 24.8 0.0 2.5e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP21861.1 - 0.059 13.6 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP21862.1 - 3.8e-09 36.5 0.0 4e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21862.1 - 1.7e-06 28.5 0.0 1.7e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP21862.1 - 0.0082 16.3 0.0 0.0099 16.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KFP21862.1 - 0.0098 16.2 0.0 0.01 16.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP21863.1 - 4e-11 42.8 0.0 4.1e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21863.1 - 2.3e-09 37.7 0.1 2.4e-09 37.7 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP21863.1 - 5.7e-05 23.2 0.2 6.5e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP21863.1 - 0.0006 20.0 0.0 0.00066 19.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KFP21863.1 - 0.00065 20.0 0.0 0.00067 19.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Receptor_2B4 PF11465.8 KFP21863.1 - 0.12 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 I-set PF07679.16 KFP21864.1 - 2.6e-80 264.6 8.3 3e-27 94.5 0.1 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP21864.1 - 1.7e-54 182.4 6.6 6.6e-16 58.7 0.1 5.7 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 KFP21864.1 - 2.3e-34 117.6 4.7 1.2e-08 35.1 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP21864.1 - 1.8e-32 111.4 10.7 2.7e-13 49.9 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KFP21864.1 - 4.3e-23 81.6 13.3 5.1e-06 26.6 0.2 8.3 5 3 0 5 5 5 5 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 KFP21864.1 - 4.4e-09 36.5 1.9 0.42 10.8 0.0 4.5 4 0 0 4 4 4 3 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 KFP21864.1 - 5.9e-09 35.9 5.3 0.0018 18.3 0.0 5.7 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP21864.1 - 9.4e-08 32.3 4.0 0.0018 18.6 0.0 5.3 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 KFP21864.1 - 1.3e-05 25.4 3.2 0.66 10.3 0.1 4.4 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KFP21864.1 - 5.1e-05 23.6 6.0 0.65 10.4 0.4 5.2 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PKD_3 PF16820.5 KFP21864.1 - 7e-05 22.5 0.1 0.22 11.3 0.0 4.4 4 1 0 4 4 4 1 PKD-like domain Egh16-like PF11327.8 KFP21864.1 - 0.011 16.2 1.5 0.32 11.4 0.1 3.0 2 1 1 3 3 3 0 Egh16-like virulence factor Ig_6 PF18452.1 KFP21864.1 - 0.098 12.2 0.1 24 4.6 0.0 4.2 5 0 0 5 5 5 0 Immunoglobulin domain DUF5640 PF18692.1 KFP21864.1 - 1 9.4 4.9 22 5.2 0.7 3.5 3 1 0 3 3 2 0 Family of unknown function (DUF5640) Thioredoxin_14 PF18402.1 KFP21864.1 - 3.1 7.7 5.0 2.4 8.1 0.9 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain PH PF00169.29 KFP21865.1 - 5.1e-10 39.8 0.0 1.1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFP21865.1 - 1.6e-05 25.2 0.3 0.00012 22.5 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KFP21865.1 - 2e-05 24.8 0.0 5.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Muted PF14942.6 KFP21865.1 - 0.016 15.6 0.5 0.032 14.6 0.5 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Cmc1 PF08583.10 KFP21865.1 - 0.063 13.3 1.6 4.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PH_6 PF15406.6 KFP21865.1 - 0.1 12.9 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF5327 PF17261.2 KFP21865.1 - 0.25 12.1 0.2 0.25 12.1 0.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5327) FKBP_C PF00254.28 KFP21866.1 - 5.2e-31 106.8 0.0 8e-31 106.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 KFP21866.1 - 1.7e-07 31.5 1.1 3.1e-07 30.8 1.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP21866.1 - 9.9e-07 28.2 2.5 0.013 15.3 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP21866.1 - 2.4e-06 26.7 2.1 0.0025 17.2 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP21866.1 - 1.1e-05 24.7 0.8 0.0026 17.2 0.2 2.6 2 0 0 2 2 2 2 EF hand Gasdermin PF04598.12 KFP21867.1 - 8e-17 61.5 0.0 9.2e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Gasdermin pore forming domain DUF4663 PF15668.5 KFP21867.1 - 0.0057 15.8 0.0 0.0063 15.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) Oxysterol_BP PF01237.18 KFP21868.1 - 3.7e-128 427.5 0.5 3.7e-128 427.5 0.5 2.2 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 KFP21868.1 - 4.5e-13 49.3 0.4 1e-12 48.1 0.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFP21868.1 - 1.8e-08 34.8 0.9 5.6e-08 33.3 0.9 1.9 1 0 0 1 1 1 1 PH domain tRNA_bind_3 PF17176.4 KFP21868.1 - 0.043 14.1 0.7 0.13 12.6 0.7 1.7 1 0 0 1 1 1 0 tRNA-binding domain PH_11 PF15413.6 KFP21868.1 - 0.047 14.1 3.8 4.2 7.9 3.8 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain RRM_1 PF00076.22 KFP21869.1 - 1.9e-28 98.1 0.0 2.5e-13 49.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP21869.1 - 0.0012 18.8 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFP21869.1 - 0.008 16.2 0.1 0.94 9.5 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KFP21869.1 - 0.1 12.6 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA binding domain RRM_occluded PF16842.5 KFP21869.1 - 0.11 12.4 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Cytochrom_C PF00034.21 KFP21870.1 - 3.8e-13 50.4 0.0 4.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFP21870.1 - 8.7e-06 26.0 0.8 3.4e-05 24.1 0.8 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFP21870.1 - 6.7e-05 22.6 0.6 0.002 17.9 0.1 2.3 2 1 0 2 2 2 1 Cytochrome c-550 domain UPF0128 PF03673.13 KFP21870.1 - 0.035 13.6 0.1 0.039 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) FAD-oxidase_C PF02913.19 KFP21871.1 - 5e-58 196.7 0.0 6.7e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFP21871.1 - 6.7e-38 129.6 0.0 5.1e-37 126.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KFP21871.1 - 0.083 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like PDGF PF00341.17 KFP21872.1 - 4.4e-26 91.0 5.6 4.4e-26 91.0 5.6 2.3 2 1 0 2 2 2 1 PDGF/VEGF domain VEGF_C PF14554.6 KFP21872.1 - 1.6e-25 88.9 14.5 1.6e-25 88.9 14.5 2.6 3 0 0 3 3 3 1 VEGF heparin-binding domain DUF3408 PF11888.8 KFP21872.1 - 0.15 12.2 3.2 0.097 12.8 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Ribosomal_L14 PF00238.19 KFP21873.1 - 3.7e-17 62.5 0.0 4.5e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e RSN1_7TM PF02714.15 KFP21874.1 - 5.4e-62 209.6 23.1 1.3e-61 208.4 23.1 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFP21874.1 - 4e-39 134.7 0.2 5.9e-39 134.1 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFP21874.1 - 2.7e-19 69.5 0.0 2.7e-19 69.5 0.0 5.6 6 1 1 7 7 7 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 KFP21874.1 - 0.043 13.6 0.1 2 8.3 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4006 PF13179.6 KFP21874.1 - 7.8 6.5 6.8 29 4.7 0.5 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Peptidase_C2 PF00648.21 KFP21875.1 - 1.3e-103 346.1 0.0 1.8e-103 345.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KFP21875.1 - 2.4e-53 180.2 0.0 4.1e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_8 PF13833.6 KFP21875.1 - 6.6e-07 29.1 0.4 7.2e-05 22.6 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP21875.1 - 4.2e-06 25.9 0.5 0.06 12.9 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KFP21875.1 - 6.7e-06 25.6 0.4 0.006 16.4 0.0 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 KFP21875.1 - 0.0015 18.9 2.8 4.2 7.9 1.1 4.0 4 1 0 4 4 4 2 EF-hand domain pair DUF3037 PF11236.8 KFP21876.1 - 0.088 13.2 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Nucleoside_tran PF01733.18 KFP21877.1 - 3.5e-103 345.2 9.1 3.5e-103 345.2 9.1 1.5 2 0 0 2 2 2 1 Nucleoside transporter HSP90 PF00183.18 KFP21878.1 - 1.2e-235 783.3 28.8 1.6e-235 782.9 28.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFP21878.1 - 3.6e-13 50.0 0.0 8.2e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP21878.1 - 4e-10 39.7 0.1 1.2e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med26 PF08711.11 KFP21878.1 - 3.7 7.7 7.4 1.9 8.6 0.0 3.5 4 0 0 4 4 4 0 TFIIS helical bundle-like domain CDC45 PF02724.14 KFP21878.1 - 7.7 4.7 14.4 14 3.8 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 KFP21878.1 - 8.1 5.7 17.0 43 3.4 14.8 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT UAA PF08449.11 KFP21879.1 - 9.1e-79 264.8 19.6 1.1e-78 264.5 19.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KFP21879.1 - 2.1e-07 31.2 22.4 0.001 19.3 15.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KFP21879.1 - 0.0037 16.3 15.1 0.04 12.9 4.7 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KFP21879.1 - 0.096 12.0 11.4 0.13 11.5 5.5 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family MNHE PF01899.16 KFP21879.1 - 0.29 10.9 4.3 0.67 9.7 0.4 2.5 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF983 PF06170.12 KFP21879.1 - 7.1 7.1 8.5 0.79 10.2 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) WASH-7_N PF14745.6 KFP21880.1 - 5.9e-240 797.7 19.4 8.6e-240 797.1 19.4 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 KFP21880.1 - 1.4e-84 284.2 5.9 1.4e-84 284.2 5.9 2.2 2 0 0 2 2 2 1 WASH complex subunit 7 Aldedh PF00171.22 KFP21882.1 - 2.3e-163 544.0 0.0 3.3e-163 543.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Formyl_trans_N PF00551.19 KFP21882.1 - 1.8e-45 154.9 0.0 4e-45 153.8 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KFP21882.1 - 2.6e-15 56.5 0.0 6.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PP-binding PF00550.25 KFP21882.1 - 4.3e-05 23.8 0.0 8.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1487 PF07368.11 KFP21882.1 - 0.0058 16.1 0.0 0.017 14.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF4598 PF15370.6 KFP21883.1 - 3.5e-15 56.4 1.5 4.6e-15 56.1 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Sigma70_r1_1 PF03979.14 KFP21883.1 - 0.0083 16.2 6.7 0.017 15.1 6.6 1.6 1 1 0 1 1 1 1 Sigma-70 factor, region 1.1 MgtE PF01769.16 KFP21885.1 - 8.4e-52 174.8 11.4 3.2e-30 105.0 0.6 3.0 4 0 0 4 4 4 2 Divalent cation transporter DUF3262 PF11660.8 KFP21885.1 - 0.27 11.7 6.8 17 5.9 0.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Sulfotransfer_2 PF03567.14 KFP21886.1 - 4.5e-69 233.2 8.3 5.7e-69 232.8 8.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family CBFD_NFYB_HMF PF00808.23 KFP21889.1 - 4e-29 100.7 0.6 5.9e-29 100.2 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFP21889.1 - 5e-06 26.9 0.0 9.6e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KFP21889.1 - 0.0013 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KFP21889.1 - 0.0032 17.6 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KFP21889.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-X PF09415.10 KFP21889.1 - 0.17 12.2 0.1 0.35 11.2 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Kelch_5 PF13854.6 KFP21890.1 - 8.9e-30 102.2 7.3 1.1e-06 28.4 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 KFP21890.1 - 4.6e-28 96.9 2.1 7.2e-08 32.5 0.0 5.5 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KFP21890.1 - 5.3e-23 80.3 10.9 5.7e-05 22.6 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP21890.1 - 2.9e-18 65.5 3.1 0.018 15.3 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KFP21890.1 - 1.6e-17 63.2 0.1 0.028 14.4 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP21890.1 - 2.5e-15 55.8 6.5 0.042 13.8 0.1 5.9 5 0 0 5 5 5 5 Kelch motif fn3 PF00041.21 KFP21890.1 - 8e-11 42.1 1.5 0.013 15.8 0.0 4.3 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP21890.1 - 0.038 14.6 1.2 0.47 11.0 0.3 3.0 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Gag_p30 PF02093.16 KFP21891.1 - 3.1e-28 98.7 0.0 3.8e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein DUF1743 PF08489.11 KFP21891.1 - 0.0013 18.8 0.0 0.037 14.1 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1743) Gag_p24 PF00607.20 KFP21891.1 - 0.028 14.3 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Glyco_transf_8 PF01501.20 KFP21892.1 - 1.1e-52 179.2 0.0 1.3e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KFP21892.1 - 3.9e-05 23.2 0.1 8.9e-05 22.0 0.1 1.6 1 1 1 2 2 2 1 Glucosyltransferase 24 UDG PF03167.19 KFP21893.1 - 2e-18 66.8 0.0 3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GAGA_bind PF06217.12 KFP21893.1 - 0.2 11.9 3.5 0.35 11.1 3.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family HSP90 PF00183.18 KFP21894.1 - 2.6e-229 762.4 28.8 4.9e-229 761.5 28.8 1.4 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFP21894.1 - 4e-15 56.3 0.4 8e-15 55.3 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP21894.1 - 4.1e-12 46.1 0.4 1.4e-11 44.4 0.4 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AbiJ_NTD5 PF18865.1 KFP21894.1 - 0.089 12.6 1.2 0.21 11.4 0.2 2.2 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 MH1 PF03165.16 KFP21894.1 - 0.24 11.6 1.7 0.87 9.8 0.0 2.8 3 0 0 3 3 3 0 MH1 domain 5_nucleotid PF05761.14 KFP21895.1 - 3.6e-155 517.3 7.2 4.1e-155 517.2 7.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 KFP21895.1 - 1.2e-05 25.5 0.3 0.00048 20.3 0.0 3.1 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Mu-transpos_C PF09299.11 KFP21895.1 - 0.047 13.7 0.6 0.79 9.7 0.1 3.1 3 0 0 3 3 3 0 Mu transposase, C-terminal Hydrolase PF00702.26 KFP21895.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fasciclin PF02469.22 KFP21896.1 - 1.7e-127 419.5 0.3 2.8e-23 82.5 0.2 7.3 7 0 0 7 7 7 7 Fasciclin domain EGF_3 PF12947.7 KFP21896.1 - 1.6e-63 210.6 396.3 4.4e-10 39.6 13.8 25.8 24 1 0 24 24 24 16 EGF domain Xlink PF00193.17 KFP21896.1 - 2.3e-27 95.2 0.3 2.3e-27 95.2 0.3 4.9 3 0 0 3 3 3 1 Extracellular link domain EGF PF00008.27 KFP21896.1 - 0.00029 21.1 5.4 0.00029 21.1 5.4 26.6 26 1 0 26 26 26 17 EGF-like domain EGF_MSP1_1 PF12946.7 KFP21896.1 - 0.00087 19.3 6.2 0.00087 19.3 6.2 23.5 24 0 0 24 24 24 9 MSP1 EGF domain 1 Dopey_N PF04118.14 KFP21898.1 - 1.4e-106 356.1 0.2 1.1e-105 353.2 0.1 2.6 2 0 0 2 2 2 1 Dopey, N-terminal NOP19 PF10863.8 KFP21899.1 - 0.066 13.0 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 19 HECT_2 PF09814.9 KFP21900.1 - 6.9e-65 219.3 0.5 8.3e-65 219.1 0.5 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RCC1 PF00415.18 KFP21904.1 - 1.4e-34 118.5 15.6 2.3e-11 44.1 1.5 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFP21904.1 - 7.9e-32 109.8 6.7 8.5e-16 58.2 1.2 3.0 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 KFP21904.1 - 1.2e-10 40.9 13.7 6.1e-05 22.7 0.0 6.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 KFP21904.1 - 4.5e-10 39.6 0.0 8.3e-06 26.0 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP21904.1 - 2.2e-08 34.5 0.0 3.8e-05 24.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP21904.1 - 2.8e-08 34.2 0.0 8.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFP21904.1 - 0.00019 21.6 0.0 1.7 9.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KFP21904.1 - 0.001 19.4 0.0 0.29 11.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Bcr-Abl_Oligo PF09036.10 KFP21904.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1265 PF06887.14 KFP21904.1 - 0.13 12.3 0.5 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) NTP_transf_7 PF07984.12 KFP21906.1 - 1.6e-133 444.9 0.4 1.8e-133 444.7 0.4 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Transket_pyr PF02779.24 KFP21907.1 - 8.2e-43 146.1 0.0 1.1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFP21907.1 - 5.6e-36 123.2 0.0 1.2e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pkinase PF00069.25 KFP21908.1 - 3.9e-64 216.6 0.9 7.3e-64 215.7 0.9 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21908.1 - 3.8e-33 114.9 0.1 7e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21908.1 - 4.2e-08 32.9 0.0 1.1e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFP21908.1 - 8.1e-06 25.9 0.2 0.18 11.7 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 KFP21908.1 - 8.7e-05 22.2 0.1 0.33 10.6 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP21908.1 - 0.00023 20.6 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFP21908.1 - 0.0013 18.4 3.4 0.01 15.4 0.1 2.4 1 1 1 2 2 2 1 RIO1 family Mad3_BUB1_I_2 PF17014.5 KFP21908.1 - 0.0026 17.9 0.2 0.0096 16.0 0.2 1.9 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Mad3_BUB1_I PF08311.12 KFP21908.1 - 0.0088 16.0 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Tubulin PF00091.25 KFP21908.1 - 0.015 15.5 0.4 0.052 13.8 0.0 1.9 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain Kinase-PolyVal PF18762.1 KFP21908.1 - 0.098 12.6 2.7 0.087 12.8 0.9 1.8 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase_fungal PF17667.1 KFP21908.1 - 0.33 9.7 3.0 0.46 9.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Lebercilin PF15619.6 KFP21909.1 - 1.7e-69 233.3 52.0 1.7e-69 233.3 52.0 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Tantalus PF15386.6 KFP21909.1 - 0.069 13.3 1.2 0.29 11.2 1.2 2.1 1 0 0 1 1 1 0 Drosophila Tantalus-like Golgin_A5 PF09787.9 KFP21909.1 - 6.1 6.2 52.8 0.89 9.0 18.4 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 SlyX PF04102.12 KFP21909.1 - 6.3 7.5 36.8 3 8.5 4.8 5.1 2 1 2 5 5 5 0 SlyX HMG14_17 PF01101.18 KFP21911.1 - 1.6e-21 77.1 22.4 1.7e-21 77.0 22.4 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.15 KFP21911.1 - 0.13 13.2 9.9 0.15 13.0 9.9 1.0 1 0 0 1 1 1 0 TT viral ORF2 DUF2477 PF10631.9 KFP21911.1 - 0.33 11.6 3.3 0.35 11.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Bromodomain PF00439.25 KFP21912.1 - 8.1e-38 128.4 0.2 4e-18 65.3 0.0 2.7 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 KFP21912.1 - 4.4e-33 112.8 15.1 3.3e-05 24.6 0.1 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21912.1 - 0.00077 19.7 0.3 0.5 10.7 0.1 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain E7 PF00527.18 KFP21912.1 - 1.6 8.9 7.9 0.19 12.0 0.1 3.5 3 0 0 3 3 3 0 E7 protein, Early protein RVT_1 PF00078.27 KFP21916.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mei4 PF13971.6 KFP21918.1 - 3.3e-79 266.9 10.9 3.8e-79 266.7 10.9 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 7tm_1 PF00001.21 KFP21919.1 - 6.8e-83 278.0 11.3 8.1e-83 277.8 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP21919.1 - 2.4e-10 40.2 10.1 2.3e-09 37.0 10.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP21919.1 - 7.3e-07 29.1 7.8 7.3e-07 29.1 7.8 2.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP21919.1 - 7.7e-07 29.1 9.2 1.9e-05 24.6 5.2 2.2 2 0 0 2 2 2 2 Olfactory receptor SEA PF01390.20 KFP21920.1 - 1.4e-31 108.7 3.7 4.4e-16 58.9 0.3 2.5 2 0 0 2 2 2 2 SEA domain DUF4214 PF13946.6 KFP21920.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) ALMS_repeat PF18727.1 KFP21920.1 - 0.032 14.1 1.2 0.12 12.2 1.2 2.1 1 0 0 1 1 1 0 Alstrom syndrome repeat EGF_3 PF12947.7 KFP21920.1 - 0.096 12.9 2.3 0.24 11.6 2.3 1.6 1 0 0 1 1 1 0 EGF domain Plasmod_Pvs28 PF06247.11 KFP21920.1 - 0.27 11.6 4.8 0.63 10.4 4.8 1.6 1 0 0 1 1 1 0 Pvs28 EGF domain EGF PF00008.27 KFP21920.1 - 0.67 10.3 9.5 1.5 9.2 1.5 2.4 2 0 0 2 2 2 0 EGF-like domain Myosin_head PF00063.21 KFP21921.1 - 2.7e-232 772.8 6.6 2.7e-232 772.8 6.6 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin-VI_CBD PF16521.5 KFP21921.1 - 1.5e-45 153.1 1.0 3.1e-44 148.9 0.0 3.2 4 0 0 4 4 4 1 Myosin VI cargo binding domain Myosin_N PF02736.19 KFP21921.1 - 0.00021 21.0 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 KFP21921.1 - 0.0017 17.9 1.5 0.0047 16.6 1.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 KFP21921.1 - 0.46 10.8 0.0 0.46 10.8 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain BUD22 PF09073.10 KFP21921.1 - 0.59 9.4 35.2 0.3 10.4 33.2 1.4 1 1 0 1 1 1 0 BUD22 AAA_22 PF13401.6 KFP21921.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.0 3 1 0 3 3 3 0 AAA domain Peptidase_C48 PF02902.19 KFP21923.1 - 9.8e-34 117.1 2.9 7e-20 71.8 1.0 2.5 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain EST1 PF10374.9 KFP21923.1 - 8.6 7.0 7.6 1.5 9.5 0.9 3.0 3 0 0 3 3 3 0 Telomerase activating protein Est1 CDC50 PF03381.15 KFP21924.1 - 9.7e-93 310.7 0.2 1.2e-92 310.5 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family COX7a PF02238.15 KFP21925.1 - 1.1e-10 41.7 0.0 2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII MFS_1 PF07690.16 KFP21928.1 - 1.2e-51 175.7 26.1 1.5e-51 175.4 26.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP21928.1 - 4.4e-08 32.4 17.5 1.5e-07 30.7 17.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_11 PF08241.12 KFP21929.1 - 7.9e-16 58.5 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP21929.1 - 2.1e-14 53.7 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP21929.1 - 3.8e-11 43.6 0.0 6.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP21929.1 - 3.9e-11 43.5 0.0 6.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP21929.1 - 3.5e-08 33.1 0.0 4.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFP21929.1 - 5.3e-07 29.6 0.0 7.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP21929.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 KFP21929.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 KFP21929.1 - 0.045 13.5 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_29 PF03141.16 KFP21929.1 - 0.046 12.3 0.1 0.059 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Trypsin PF00089.26 KFP21930.1 - 7.3e-63 212.3 0.4 8e-63 212.2 0.4 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP21930.1 - 4.6e-06 27.6 0.1 7.1e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP21930.1 - 2.5e-05 24.6 0.0 4.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) bZIP_1 PF00170.21 KFP21931.1 - 2.9e-21 75.3 9.0 4.7e-21 74.7 9.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.17 KFP21931.1 - 1.1e-18 66.4 5.6 3e-18 65.0 5.6 1.8 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.15 KFP21931.1 - 6.5e-09 35.7 8.1 1.2e-08 34.9 8.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP21931.1 - 0.00024 21.6 4.8 0.00065 20.2 4.8 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 KFP21931.1 - 0.014 14.9 1.9 0.014 14.9 1.9 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Rh5 PF18515.1 KFP21931.1 - 0.034 13.5 1.5 0.046 13.0 1.5 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain La PF05383.17 KFP21932.1 - 3.3e-18 65.5 0.2 6.3e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 La domain LIM PF00412.22 KFP21933.1 - 3.7e-12 46.3 3.6 7.5e-12 45.3 3.6 1.6 1 0 0 1 1 1 1 LIM domain TRAM_LAG1_CLN8 PF03798.16 KFP21934.1 - 3.2e-41 141.3 29.2 3.7e-41 141.1 29.2 1.0 1 0 0 1 1 1 1 TLC domain Homeodomain PF00046.29 KFP21934.1 - 1.7e-06 27.7 0.1 3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain NAD_Gly3P_dh_N PF01210.23 KFP21935.1 - 5.9e-56 188.8 0.4 1.7e-55 187.3 0.2 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KFP21935.1 - 5.5e-50 169.3 0.5 1.1e-49 168.4 0.2 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KFP21935.1 - 0.0018 18.8 2.9 0.035 14.7 0.3 3.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GerD PF17898.1 KFP21935.1 - 0.11 12.4 0.2 1.4 8.9 0.0 2.2 2 1 0 2 2 2 0 Spore germination GerD central core domain KH_1 PF00013.29 KFP21935.1 - 0.23 11.3 2.4 0.25 11.2 0.0 2.3 3 0 0 3 3 3 0 KH domain SWIB PF02201.18 KFP21936.1 - 5.5e-25 87.0 0.2 1.4e-24 85.7 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain ASC PF00858.24 KFP21937.1 - 3.7e-107 359.1 0.2 4.4e-107 358.8 0.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4074 PF13293.6 KFP21937.1 - 0.23 11.8 1.0 0.41 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) RhoGAP PF00620.27 KFP21938.1 - 1.5e-43 148.2 0.0 3.1e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KFP21938.1 - 1.3e-07 31.4 2.9 2.4e-07 30.5 2.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Cep57_CLD PF14073.6 KFP21938.1 - 0.0061 16.6 4.3 0.012 15.7 4.3 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 TonB_2 PF13103.6 KFP21938.1 - 0.012 15.9 0.1 0.035 14.3 0.1 1.8 1 0 0 1 1 1 0 TonB C terminal DUF2968 PF11180.8 KFP21938.1 - 0.052 13.2 7.9 0.088 12.4 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) zf-CCHC_6 PF15288.6 KFP21938.1 - 0.13 12.2 2.1 0.32 10.9 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C4H2 PF10146.9 KFP21938.1 - 2.8 8.2 7.7 0.091 13.1 0.8 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein MFS_1 PF07690.16 KFP21939.1 - 4.8e-14 52.0 22.3 1.5e-12 47.2 3.7 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFP21939.1 - 1.6e-09 36.8 1.4 1.6e-09 36.8 1.4 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein DUF5367 PF17329.2 KFP21939.1 - 0.29 11.3 1.6 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5367) Inhibitor_Mig-6 PF11555.8 KFP21940.1 - 1.1e-14 54.3 8.9 1.1e-14 54.3 8.9 3.2 3 0 0 3 3 3 2 EGFR receptor inhibitor Mig-6 GTPase_binding PF09027.10 KFP21940.1 - 0.00012 22.0 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 GTPase binding DJ-1_PfpI PF01965.24 KFP21941.1 - 7e-53 178.8 0.0 8e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFP21941.1 - 0.00053 19.7 0.0 0.044 13.5 0.0 2.2 1 1 1 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 KFP21941.1 - 0.0074 15.9 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain TNFR_c6 PF00020.18 KFP21942.1 - 1.4e-07 31.7 20.3 5e-06 26.8 1.3 3.2 3 0 0 3 3 3 2 TNFR/NGFR cysteine-rich region VSP PF03302.13 KFP21942.1 - 0.028 13.3 19.8 0.034 13.0 19.8 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Urotensin_II PF02083.15 KFP21943.1 - 1.1e-06 27.9 1.0 2.6e-06 26.7 1.0 1.7 1 0 0 1 1 1 1 Urotensin II Period_C PF12114.8 KFP21944.1 - 1.1e-31 109.9 21.4 1.1e-31 109.9 21.4 3.8 3 1 0 3 3 3 1 Period protein 2/3C-terminal region PAS_3 PF08447.12 KFP21944.1 - 2.7e-15 56.4 0.0 1.8e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KFP21944.1 - 1.7e-09 37.8 0.0 6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KFP21944.1 - 5.4e-09 36.1 0.0 7.5e-07 29.2 0.0 2.9 2 1 0 2 2 2 1 PAS fold GCN5L1 PF06320.13 KFP21944.1 - 3.4 7.9 5.9 3 8.0 2.9 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Synaptobrevin PF00957.21 KFP21945.1 - 1e-34 118.2 4.1 1.1e-34 118.0 4.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KFP21945.1 - 0.015 15.4 0.1 0.017 15.2 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter ASFV_J13L PF05568.11 KFP21945.1 - 6.2 6.5 7.7 7.8 6.2 7.2 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein CG-1 PF03859.16 KFP21946.1 - 8.8e-34 115.8 1.1 2.6e-33 114.3 1.1 1.9 1 0 0 1 1 1 1 CG-1 domain TIG PF01833.24 KFP21946.1 - 1.1e-10 41.4 1.3 3e-10 40.0 0.1 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 KFP21946.1 - 2.2e-09 37.8 0.1 5.8e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP21946.1 - 4.5e-05 23.6 0.7 0.53 10.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP21946.1 - 0.00026 21.2 0.5 0.94 10.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat IQ PF00612.27 KFP21946.1 - 0.0016 18.1 18.7 0.8 9.7 0.3 5.5 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_4 PF13637.6 KFP21946.1 - 0.0035 17.9 1.2 0.31 11.7 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KFP21946.1 - 0.012 16.1 0.3 3.4 8.3 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat DUF3395 PF11875.8 KFP21947.1 - 1.2e-46 158.4 0.4 1.2e-46 158.4 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KFP21947.1 - 1.8e-17 63.2 1.7 3.8e-17 62.1 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain DUF4736 PF15883.5 KFP21947.1 - 0.089 12.5 1.4 0.17 11.6 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) GDA1_CD39 PF01150.17 KFP21947.1 - 0.14 10.8 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family PHD PF00628.29 KFP21948.1 - 3.4e-08 33.3 8.2 5.9e-08 32.5 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFP21948.1 - 3.8e-06 26.4 5.3 6.9e-06 25.5 5.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-C4H2 PF10146.9 KFP21948.1 - 0.0041 17.5 0.2 0.0064 16.8 0.2 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein zf-HC5HC2H PF13771.6 KFP21948.1 - 0.014 15.6 1.1 0.031 14.5 1.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 KFP21948.1 - 0.017 15.0 2.0 0.017 15.0 2.0 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KFP21948.1 - 0.77 9.7 6.8 1.4 8.9 6.8 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-H2C2_2 PF13465.6 KFP21949.1 - 6.6e-58 190.7 85.1 1.7e-09 37.7 1.9 12.1 12 0 0 12 12 12 10 Zinc-finger double domain zf-C2H2 PF00096.26 KFP21949.1 - 2.6e-38 128.4 93.0 4.8e-06 26.7 1.9 11.3 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP21949.1 - 9.8e-31 103.8 90.5 0.0015 19.2 1.6 11.4 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFP21949.1 - 2.9e-09 36.7 78.3 7.3e-05 22.7 2.2 10.5 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFP21949.1 - 2.3e-07 30.9 55.6 0.0039 17.4 0.4 10.5 11 0 0 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP21949.1 - 1.4e-06 28.4 69.6 0.052 14.0 0.9 10.7 11 0 0 11 11 10 5 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFP21949.1 - 5.2e-06 26.1 4.8 9.3e-05 22.1 0.6 8.6 10 0 0 10 10 10 2 zinc-finger C2H2-type zf-Di19 PF05605.12 KFP21949.1 - 2.1e-05 24.7 64.6 0.00075 19.8 1.6 7.3 3 2 2 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFP21949.1 - 0.0018 18.0 4.6 0.0086 15.8 0.6 9.4 9 1 0 9 9 9 4 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KFP21949.1 - 0.0019 18.5 51.2 0.32 11.3 2.5 6.1 1 1 5 6 6 6 3 C2H2-type zinc ribbon GAGA PF09237.11 KFP21949.1 - 0.0061 16.3 4.7 0.044 13.6 0.6 6.7 2 2 5 8 8 8 3 GAGA factor zinc_ribbon_15 PF17032.5 KFP21949.1 - 0.027 15.2 41.9 0.41 11.4 1.2 6.0 2 1 3 6 6 6 0 zinc-ribbon family DUF2387 PF09526.10 KFP21949.1 - 0.08 13.1 0.3 0.08 13.1 0.3 4.1 4 1 1 5 5 5 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 KFP21949.1 - 0.19 11.9 58.1 1.9 8.7 1.8 9.1 6 2 3 9 9 8 0 Zinc ribbon domain DUF3268 PF11672.8 KFP21949.1 - 0.21 11.9 30.0 0.72 10.2 0.4 5.4 4 1 3 7 7 7 0 zinc-finger-containing domain zf-C2H2_2 PF12756.7 KFP21949.1 - 0.65 10.4 64.9 0.15 12.4 8.3 9.2 1 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KFP21949.1 - 0.78 10.4 41.1 0.58 10.8 0.8 7.2 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats ANF_receptor PF01094.28 KFP21950.1 - 1.6e-44 152.5 0.0 2.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region NCD3G PF07562.14 KFP21950.1 - 1.8e-13 50.2 11.3 1.8e-13 50.2 11.3 2.1 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR 7tm_3 PF00003.22 KFP21950.1 - 5.2e-10 39.5 13.1 9e-10 38.7 13.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 KFP21950.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein CLP1_P PF16575.5 KFP21951.1 - 1.7e-14 54.0 0.0 2.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFP21951.1 - 0.064 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Ribosomal_S2 PF00318.20 KFP21952.1 - 1.5e-26 93.0 0.0 1.6e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KFP21952.1 - 1.1e-24 87.6 15.8 2.1e-24 86.7 15.8 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Mito_carr PF00153.27 KFP21953.1 - 1.1e-57 191.9 8.9 2.9e-20 72.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.16 KFP21953.1 - 0.021 14.6 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component 7tm_1 PF00001.21 KFP21954.1 - 5.9e-54 183.1 23.5 8e-54 182.7 23.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP21954.1 - 1.9e-09 37.3 25.8 2.9e-09 36.7 25.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Glyco_hydro_35 PF01301.19 KFP21955.1 - 2.6e-103 346.0 0.0 3.5e-103 345.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFP21955.1 - 5.3e-13 49.0 0.0 2.4e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KFP21955.1 - 8.1e-07 29.6 0.7 1.2e-05 25.8 0.0 2.9 3 1 1 4 4 4 1 Beta-galactosidase jelly roll domain Metallophos PF00149.28 KFP21956.1 - 2.9e-14 54.0 0.1 3.9e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP21956.1 - 8.2e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Xlink PF00193.17 KFP21958.1 - 1.1e-14 54.5 0.2 1.1e-14 54.5 0.2 1.9 2 0 0 2 2 2 1 Extracellular link domain Sushi PF00084.20 KFP21958.1 - 0.00019 21.9 0.8 0.00019 21.9 0.8 2.2 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) SIT PF15330.6 KFP21958.1 - 0.0047 17.4 0.7 0.014 15.8 0.2 2.1 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT GAPT PF11770.8 KFP21958.1 - 0.0049 16.8 0.2 0.0099 15.8 0.2 1.5 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) EphA2_TM PF14575.6 KFP21958.1 - 0.074 13.9 0.3 0.22 12.5 0.3 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.10 KFP21958.1 - 0.082 13.3 0.4 0.19 12.1 0.4 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4366 PF14283.6 KFP21958.1 - 0.094 12.8 0.1 0.094 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) ERGIC_N PF13850.6 KFP21958.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Insulin_TMD PF17870.1 KFP21958.1 - 0.21 11.6 1.7 0.51 10.4 1.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_6 PF13516.6 KFP21959.1 - 4.2e-20 70.0 39.0 6.5e-05 22.7 0.1 10.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 KFP21959.1 - 6.8e-15 55.0 23.4 0.028 14.9 0.8 7.1 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFP21959.1 - 3.3e-08 33.3 0.6 1.4e-07 31.2 0.6 2.1 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KFP21959.1 - 6.5e-06 26.0 34.0 0.22 12.2 0.1 10.5 10 1 0 10 10 10 2 Leucine Rich Repeat F-box PF00646.33 KFP21959.1 - 3.7e-05 23.5 1.4 0.00013 21.7 0.3 2.6 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KFP21959.1 - 0.0026 17.5 18.4 0.53 10.1 2.5 6.2 5 3 1 6 6 6 3 Leucine rich repeat Mating_N PF12731.7 KFP21959.1 - 0.047 13.8 0.1 1.5 8.9 0.1 2.6 1 1 0 2 2 2 0 Mating-type protein beta 1 PTE PF02126.18 KFP21959.1 - 0.086 12.3 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Phosphotriesterase family CP2 PF04516.15 KFP21960.1 - 1.7e-58 197.6 0.0 2.5e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KFP21960.1 - 2.3e-20 72.1 0.0 3.8e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP21960.1 - 0.0082 16.2 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFP21960.1 - 0.0088 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 KFP21960.1 - 0.028 14.9 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RGS_DHEX PF18148.1 KFP21961.1 - 3.9e-41 139.2 4.3 9.1e-41 138.0 4.3 1.6 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KFP21961.1 - 9.2e-33 113.0 0.0 1.6e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KFP21961.1 - 3.2e-08 33.5 0.0 1.3e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KFP21961.1 - 8.3e-08 32.1 0.0 7e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 GGL domain MNR PF15718.5 KFP21961.1 - 0.087 10.9 0.2 0.12 10.5 0.2 1.1 1 0 0 1 1 1 0 Protein moonraker MFS_1 PF07690.16 KFP21962.1 - 5.4e-39 134.1 17.4 2.1e-36 125.6 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP21962.1 - 0.0019 17.1 27.8 0.016 14.1 10.1 2.7 2 2 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 KFP21963.1 - 0.00024 21.8 0.0 4.6 8.3 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21963.1 - 0.0021 18.3 0.0 1.6 9.1 0.0 3.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BCAS3 PF12490.8 KFP21963.1 - 0.03 13.9 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 cNMP_binding PF00027.29 KFP21964.1 - 5.9e-39 132.0 0.1 2.4e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KFP21964.1 - 5.1e-14 51.6 0.1 1.1e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 KFP21964.1 - 0.028 14.1 1.6 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.12 KFP21964.1 - 0.7 9.6 2.6 18 5.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ABC_tran PF00005.27 KFP21965.1 - 5.9e-59 198.5 0.1 3.4e-29 102.1 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFP21965.1 - 8e-32 110.7 52.3 7.3e-25 87.8 21.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFP21965.1 - 1e-15 58.3 3.6 7.6e-06 25.9 0.0 4.8 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP21965.1 - 7.9e-10 38.9 1.8 0.00029 20.8 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KFP21965.1 - 5.7e-05 22.7 1.9 0.0055 16.2 0.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFP21965.1 - 0.00021 21.0 2.8 0.37 10.6 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP21965.1 - 0.001 19.5 0.1 0.34 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KFP21965.1 - 0.0017 18.9 5.6 0.8 10.2 0.7 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFP21965.1 - 0.0043 16.8 0.2 1.2 8.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFP21965.1 - 0.006 16.6 2.4 2.4 8.3 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF4162 PF13732.6 KFP21965.1 - 0.0069 17.1 0.0 0.69 10.7 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) Rad17 PF03215.15 KFP21965.1 - 0.0089 16.0 0.3 0.67 9.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KFP21965.1 - 0.035 14.4 0.3 4.1 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KFP21965.1 - 0.11 12.2 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3969 PF13108.6 KFP21965.1 - 0.12 12.4 0.8 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) T2SSE PF00437.20 KFP21965.1 - 0.15 11.1 0.2 10 5.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DLIC PF05783.11 KFP21965.1 - 0.19 10.5 0.0 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) cobW PF02492.19 KFP21965.1 - 0.26 10.9 0.6 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KFP21965.1 - 2.5 7.7 6.7 3.3 7.3 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 KFP21966.1 - 1.2e-59 200.8 0.0 6.1e-29 101.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFP21966.1 - 2.5e-43 148.5 54.1 2.5e-29 102.5 21.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFP21966.1 - 1.2e-15 58.1 0.0 0.00053 19.9 0.0 4.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFP21966.1 - 3.7e-10 40.0 0.2 0.0008 19.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFP21966.1 - 1.5e-06 27.8 0.4 0.078 12.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFP21966.1 - 3.5e-06 27.5 0.0 0.092 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFP21966.1 - 8.2e-06 25.9 0.1 0.11 12.6 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFP21966.1 - 6e-05 23.6 8.0 0.056 13.9 0.2 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFP21966.1 - 0.00021 21.6 0.7 1.4 9.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFP21966.1 - 0.00082 19.2 0.3 1.5 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KFP21966.1 - 0.00085 18.6 0.9 4.2 6.5 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain SMC_N PF02463.19 KFP21966.1 - 0.0013 18.2 0.1 4.9 6.5 0.1 3.8 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KFP21966.1 - 0.0016 18.1 0.5 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KFP21966.1 - 0.0024 18.0 0.0 0.046 13.8 0.0 2.7 2 1 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KFP21966.1 - 0.0029 17.3 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFP21966.1 - 0.003 17.3 0.0 1.9 8.2 0.0 3.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_5 PF07728.14 KFP21966.1 - 0.0043 17.0 0.7 2.1 8.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFP21966.1 - 0.0058 17.0 0.1 3.5 8.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KFP21966.1 - 0.0065 16.9 0.0 3.8 7.9 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFP21966.1 - 0.0086 16.0 0.6 0.45 10.4 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain NACHT PF05729.12 KFP21966.1 - 0.011 15.6 0.2 12 5.8 0.2 3.2 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 KFP21966.1 - 0.015 15.5 0.2 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFP21966.1 - 0.02 14.9 0.5 9.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFP21966.1 - 0.025 14.3 0.1 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFP21966.1 - 0.035 13.6 0.3 4.6 6.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KFP21966.1 - 0.047 12.8 0.1 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4162 PF13732.6 KFP21966.1 - 0.063 14.0 0.5 2.3 9.0 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) MobB PF03205.14 KFP21966.1 - 0.082 12.8 0.2 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 KFP21966.1 - 0.084 12.4 0.3 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KFP21966.1 - 0.12 12.6 0.2 25 5.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pullulanase_Ins PF18494.1 KFP21966.1 - 0.13 12.7 0.1 0.58 10.7 0.1 2.1 1 0 0 1 1 1 0 Pullulanase Ins domain Mg_chelatase PF01078.21 KFP21966.1 - 0.15 11.5 0.3 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 KFP21966.1 - 0.17 11.5 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KFP21966.1 - 0.19 10.9 1.3 9 5.5 0.0 3.0 3 0 0 3 3 3 0 Septin FeoB_N PF02421.18 KFP21966.1 - 0.22 11.1 0.7 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 KFP21966.1 - 0.55 10.5 1.5 26 5.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KFP21966.1 - 0.68 9.0 3.3 20 4.2 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase Pkinase PF00069.25 KFP21967.1 - 1e-48 166.0 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP21967.1 - 2.9e-33 115.3 0.0 3.5e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21967.1 - 6e-05 22.5 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFP21967.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP21967.1 - 0.0032 16.6 0.2 0.0046 16.0 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFP21967.1 - 0.0035 16.2 0.1 0.0085 14.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP21967.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP21967.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CLP1_P PF16575.5 KFP21967.1 - 0.045 13.5 0.1 0.092 12.5 0.1 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4344 PF14247.6 KFP21967.1 - 0.073 12.7 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase PIP49_C PF12260.8 KFP21967.1 - 0.12 11.9 0.0 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 IRK_C PF17655.1 KFP21968.1 - 2.7e-62 209.5 0.0 4.1e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP21968.1 - 4e-57 192.0 7.4 6.1e-57 191.4 7.4 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 KFP21968.1 - 0.0034 17.3 6.5 0.008 16.1 6.4 1.8 1 1 0 1 1 1 1 Ion channel IRK_C PF17655.1 KFP21969.1 - 2.9e-77 258.2 0.0 4.3e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 KFP21969.1 - 1.8e-64 215.8 6.2 2.6e-64 215.3 6.2 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_N PF08466.10 KFP21969.1 - 1.7e-26 92.1 1.3 3.5e-26 91.1 1.3 1.6 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.16 KFP21969.1 - 0.0011 18.8 6.4 0.0027 17.6 6.4 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KFP21969.1 - 0.0033 16.7 5.4 0.0047 16.2 5.4 1.2 1 0 0 1 1 1 1 Ion transport protein Zip PF02535.22 KFP21970.1 - 2.2e-24 86.3 10.7 5.6e-24 85.0 10.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter CbtB PF09489.10 KFP21970.1 - 2.9 8.1 8.7 7.2 6.8 0.5 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF3510 PF12022.8 KFP21971.1 - 0.01 16.2 0.0 0.045 14.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Cdc6_C PF09079.11 KFP21971.1 - 0.12 12.3 0.1 0.64 10.0 0.1 2.2 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain FAM104 PF15434.6 KFP21972.1 - 1.1e-49 167.5 8.5 1.5e-49 167.1 8.5 1.2 1 0 0 1 1 1 1 Family 104 Chorion_2 PF03964.15 KFP21972.1 - 0.068 14.0 3.8 0.082 13.7 3.8 1.3 1 0 0 1 1 1 0 Chorion family 2 SR-25 PF10500.9 KFP21972.1 - 5.1 6.6 20.8 7 6.2 20.8 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein WRW PF10206.9 KFP21973.1 - 2.6e-13 50.2 0.0 3.2e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f F1F0-ATPsyn_F PF10791.9 KFP21973.1 - 0.081 13.4 0.1 0.1 13.1 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi zf-CCCH PF00642.24 KFP21974.1 - 3.4e-19 68.3 32.8 0.00043 20.1 1.6 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFP21974.1 - 2.9e-15 55.7 42.8 2.5e-05 24.2 3.5 6.0 5 1 0 5 5 5 5 Zinc finger domain Torus PF16131.5 KFP21974.1 - 4.4e-11 43.4 28.0 0.0012 19.5 0.3 5.0 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 KFP21974.1 - 2.1e-08 34.3 9.8 2.1e-08 34.3 9.8 2.5 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KFP21974.1 - 1e-06 28.4 34.8 2e-05 24.3 0.9 4.9 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFP21974.1 - 0.0067 16.9 40.2 1.1 9.8 1.7 5.9 5 1 0 5 5 5 4 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 KFP21974.1 - 3.6 7.4 20.5 0.36 10.6 0.4 5.4 5 1 0 5 5 5 0 Putative zinc-finger domain Acyltransf_C PF16076.5 KFP21975.1 - 8e-16 57.9 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 KFP21975.1 - 3.9e-07 29.7 0.1 6.5e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase HEAT_2 PF13646.6 KFP21976.1 - 0.00042 20.7 3.6 0.25 11.8 0.1 4.6 4 0 0 4 4 4 1 HEAT repeats TPR_6 PF13174.6 KFP21976.1 - 0.0046 17.5 1.4 2.2 9.1 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Paz_1 PF18349.1 KFP21976.1 - 0.035 14.1 0.0 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 PAZ domain SPG48 PF14764.6 KFP21976.1 - 0.11 13.0 2.9 0.31 11.5 0.2 3.3 3 1 1 4 4 4 0 AP-5 complex subunit, vesicle trafficking TPR_2 PF07719.17 KFP21976.1 - 0.22 11.7 0.5 12 6.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3453 PF11935.8 KFP21976.1 - 0.37 10.4 5.1 1.5 8.4 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3453) WD40 PF00400.32 KFP21977.1 - 1.3e-24 85.9 13.3 9e-06 26.3 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP21977.1 - 2.8e-05 24.3 1.5 0.058 13.7 0.1 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain B56 PF01603.20 KFP21978.1 - 1.1e-189 630.7 10.6 1.3e-189 630.5 10.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFP21978.1 - 0.087 12.7 4.5 0.95 9.3 0.2 3.4 1 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TMEM206 PF15122.6 KFP21979.1 - 3.1e-171 568.3 3.7 3.5e-171 568.1 3.7 1.0 1 0 0 1 1 1 1 TMEM206 protein family Tetraspanin PF00335.20 KFP21979.1 - 0.039 13.6 0.4 0.06 13.0 0.0 1.6 2 0 0 2 2 2 0 Tetraspanin family Cyt-b5 PF00173.28 KFP21980.1 - 8.4e-11 41.9 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RVT_1 PF00078.27 KFP21981.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) bZIP_1 PF00170.21 KFP21982.1 - 7.3e-12 45.2 18.2 1.4e-11 44.3 18.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP21982.1 - 1.1e-09 38.2 19.2 1.7e-09 37.6 19.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP21982.1 - 4.1e-08 33.6 7.9 9.3e-08 32.5 7.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Dapper PF15268.6 KFP21982.1 - 0.0052 15.7 2.9 0.0054 15.7 2.9 1.0 1 0 0 1 1 1 1 Dapper SNAPc19 PF15497.6 KFP21982.1 - 0.013 15.9 1.1 0.013 15.9 1.1 2.2 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ribosomal_L6e PF01159.19 KFP21982.1 - 0.061 13.9 7.3 0.074 13.6 5.5 1.8 1 1 1 2 2 2 0 Ribosomal protein L6e DivIC PF04977.15 KFP21982.1 - 0.21 11.4 6.7 0.41 10.4 6.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Afi1 PF07792.12 KFP21982.1 - 0.79 10.2 6.3 1.2 9.6 6.3 1.4 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Fungal_TACC PF12709.7 KFP21982.1 - 1.1 9.7 9.2 1.2 9.6 8.2 1.6 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Macoilin PF09726.9 KFP21982.1 - 1.3 7.4 11.5 1.7 7.1 11.5 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_1 PF00170.21 KFP21983.1 - 5.7e-13 48.7 12.7 6.9e-13 48.5 12.7 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP21983.1 - 4e-10 39.6 13.1 5.1e-10 39.3 13.1 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP21983.1 - 2.9e-09 37.3 10.1 3.6e-09 37.0 10.1 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 KFP21983.1 - 5.1e-05 23.4 1.9 9.6e-05 22.5 1.9 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper SYCE1 PF15233.6 KFP21983.1 - 0.0062 16.6 5.7 0.0062 16.6 5.7 1.5 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 TLE_N PF03920.15 KFP21983.1 - 0.0067 16.5 1.7 0.0076 16.3 1.7 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HAUS-augmin3 PF14932.6 KFP21983.1 - 0.0075 15.9 2.1 0.0085 15.7 2.1 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 HAP1_N PF04849.13 KFP21983.1 - 0.0077 15.5 7.0 0.0085 15.3 7.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TPD52 PF04201.15 KFP21983.1 - 0.0087 15.7 3.3 0.0092 15.6 2.8 1.3 1 1 0 1 1 1 1 Tumour protein D52 family DivIC PF04977.15 KFP21983.1 - 0.0087 15.8 4.6 0.012 15.4 4.6 1.4 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.8 KFP21983.1 - 0.012 15.6 8.9 0.015 15.3 8.8 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Baculo_gp64 PF03273.13 KFP21983.1 - 0.017 13.9 1.0 0.02 13.7 1.0 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Prominin PF05478.11 KFP21983.1 - 0.018 13.1 1.0 0.018 13.0 1.0 1.0 1 0 0 1 1 1 0 Prominin Ribosomal_L30_N PF08079.12 KFP21983.1 - 0.019 15.2 9.9 0.025 14.8 9.9 1.1 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Cnn_1N PF07989.11 KFP21983.1 - 0.021 15.0 6.1 0.021 15.0 6.1 1.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KFP21983.1 - 0.024 15.1 5.3 0.024 15.1 5.3 1.6 1 1 1 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KFP21983.1 - 0.025 15.0 3.9 0.03 14.7 3.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Rootletin PF15035.6 KFP21983.1 - 0.026 14.5 7.1 0.032 14.2 7.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Rx_N PF18052.1 KFP21983.1 - 0.027 14.7 1.6 0.035 14.4 0.9 1.4 1 1 0 1 1 1 0 Rx N-terminal domain JIP_LZII PF16471.5 KFP21983.1 - 0.044 14.0 3.2 0.044 14.0 3.2 1.6 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 KFP21983.1 - 0.047 13.0 5.9 0.054 12.8 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KFP21983.1 - 0.051 13.8 11.1 0.065 13.4 11.1 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FapA PF03961.13 KFP21983.1 - 0.062 11.9 3.9 0.065 11.8 3.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 KFP21983.1 - 0.066 13.0 2.8 0.078 12.8 2.8 1.0 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KFP21983.1 - 0.072 11.7 5.4 0.082 11.5 5.4 1.0 1 0 0 1 1 1 0 AAA domain NYD-SP28_assoc PF14775.6 KFP21983.1 - 0.08 13.1 1.7 0.5 10.5 0.6 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF1465 PF07323.12 KFP21983.1 - 0.08 12.8 3.9 0.094 12.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Seryl_tRNA_N PF02403.22 KFP21983.1 - 0.082 13.1 5.5 0.1 12.8 5.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KFP21983.1 - 0.085 12.2 2.0 0.094 12.1 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phlebovirus_NSM PF07246.11 KFP21983.1 - 0.093 12.1 2.9 0.098 12.0 2.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMPIT PF07851.13 KFP21983.1 - 0.1 11.8 4.8 0.11 11.7 4.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF2009 PF09418.10 KFP21983.1 - 0.11 11.6 1.9 0.12 11.4 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) TerB PF05099.13 KFP21983.1 - 0.12 12.3 2.4 0.15 12.0 2.4 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB DUF2205 PF10224.9 KFP21983.1 - 0.17 11.9 4.8 0.23 11.5 4.8 1.3 1 0 0 1 1 1 0 Short coiled-coil protein TMCO5 PF14992.6 KFP21983.1 - 0.18 11.4 5.6 0.19 11.3 5.6 1.1 1 0 0 1 1 1 0 TMCO5 family RmuC PF02646.16 KFP21983.1 - 0.2 10.8 6.0 0.25 10.5 6.0 1.1 1 0 0 1 1 1 0 RmuC family DUF1515 PF07439.11 KFP21983.1 - 0.31 11.1 2.1 0.41 10.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) APG6_N PF17675.1 KFP21983.1 - 0.4 11.2 10.1 0.51 10.9 10.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KFP21983.1 - 0.56 8.1 2.5 0.61 7.9 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps5 PF09325.10 KFP21983.1 - 0.57 9.7 8.3 0.63 9.5 8.3 1.1 1 0 0 1 1 1 0 Vps5 C terminal like HlyD_2 PF12700.7 KFP21983.1 - 0.59 8.8 5.8 0.66 8.6 5.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein LCD1 PF09798.9 KFP21983.1 - 0.81 8.1 5.3 0.85 8.1 5.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Cep57_CLD_2 PF14197.6 KFP21983.1 - 1.6 8.9 12.7 0.082 13.0 2.5 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 KFP21983.1 - 1.7 8.7 8.0 1.9 8.5 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Casc1_N PF15927.5 KFP21983.1 - 1.9 8.1 10.8 2.4 7.8 10.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Mis14 PF08641.12 KFP21984.1 - 5.4e-22 78.5 1.6 9e-22 77.8 1.6 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like TatD_DNase PF01026.21 KFP21985.1 - 2.2e-43 148.5 0.0 2.4e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase MFS_1 PF07690.16 KFP21986.1 - 7.1e-20 71.2 37.4 2.9e-19 69.2 23.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UL45 PF05473.12 KFP21986.1 - 2.1 8.0 5.7 2.2 7.9 0.1 3.0 3 1 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like OATP PF03137.20 KFP21986.1 - 7.3 4.7 16.5 0.16 10.2 8.0 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Exo_endo_phos PF03372.23 KFP21987.1 - 9.4e-26 90.7 0.0 1.4e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFP21987.1 - 0.012 15.4 0.5 0.14 12.0 0.0 2.9 4 0 0 4 4 4 0 Endonuclease-reverse transcriptase Pkinase PF00069.25 KFP21988.1 - 5.2e-29 101.4 0.0 1.9e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.18 KFP21988.1 - 2.9e-18 65.7 0.9 5.3e-18 64.8 0.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.24 KFP21988.1 - 2.4e-12 46.8 0.4 4.3e-12 46.0 0.4 1.4 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 KFP21988.1 - 1.9e-11 43.8 0.0 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP21988.1 - 2.4e-05 23.8 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like USP8_dimer PF08969.11 KFP21988.1 - 0.094 12.9 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain Kdo PF06293.14 KFP21988.1 - 0.2 11.0 0.1 0.36 10.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HPD PF05044.12 KFP21990.1 - 8.1e-84 279.1 2.0 1.4e-83 278.3 2.0 1.4 1 0 0 1 1 1 1 Homeo-prospero domain NifQ PF04891.12 KFP21990.1 - 0.016 15.6 3.5 0.48 10.8 0.0 3.4 3 0 0 3 3 3 0 NifQ Metal_resist PF13801.6 KFP21990.1 - 0.23 11.7 9.8 0.31 11.2 8.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance FliD_N PF02465.18 KFP21990.1 - 0.29 11.9 4.4 8.3 7.2 5.6 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AATF-Che1 PF13339.6 KFP21990.1 - 0.46 11.2 9.5 2.1 9.1 9.4 2.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.15 KFP21990.1 - 0.7 9.4 6.1 1.4 8.5 6.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFP21990.1 - 1.1 7.8 3.9 1.7 7.2 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 KFP21990.1 - 1.3 8.7 15.8 2.4 7.7 15.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) WDCP PF15390.6 KFP21990.1 - 1.9 6.8 8.8 2.9 6.2 8.8 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Nop25 PF09805.9 KFP21990.1 - 2.8 8.4 18.8 6.1 7.3 18.8 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) PP_kinase_N PF13089.6 KFP21990.1 - 3.4 8.1 10.9 4.8 7.6 5.3 3.3 2 1 1 3 3 3 0 Polyphosphate kinase N-terminal domain DUF4407 PF14362.6 KFP21990.1 - 5.7 6.2 8.4 9 5.6 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SET PF00856.28 KFP21992.1 - 2.5e-11 44.3 0.1 4.8e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.6 KFP21992.1 - 2.3e-05 24.6 0.1 0.00029 21.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP21992.1 - 0.00088 19.1 0.2 0.0032 17.3 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFP21992.1 - 0.0075 16.4 0.1 0.02 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP21992.1 - 0.012 16.4 0.4 0.1 13.5 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP21992.1 - 0.072 13.2 0.4 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Y_phosphatase PF00102.27 KFP21993.1 - 4.7e-76 255.4 0.7 9.4e-76 254.5 0.7 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.18 KFP21993.1 - 6.9e-21 74.8 3.5 9.3e-21 74.4 0.3 2.6 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KFP21993.1 - 1.4e-18 66.5 0.1 3.6e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KFP21993.1 - 2.3e-10 40.7 1.2 6.2e-10 39.3 0.5 2.2 2 0 0 2 2 2 1 FERM C-terminal PH-like domain DSPc PF00782.20 KFP21993.1 - 2.9e-05 23.9 0.0 8.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP21993.1 - 0.00056 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP21993.1 - 0.039 14.1 2.9 0.18 11.9 0.0 3.1 3 0 0 3 3 3 0 Inositol hexakisphosphate CENP-F_N PF10481.9 KFP21994.1 - 1.7e-70 238.1 27.7 1.9e-70 238.0 27.7 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain Fez1 PF06818.15 KFP21994.1 - 0.0002 21.9 19.5 0.00024 21.6 19.5 1.0 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 KFP21994.1 - 0.0047 15.9 22.5 0.0053 15.7 22.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2514 PF10721.9 KFP21994.1 - 0.0048 16.9 3.0 0.005 16.9 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) ATG16 PF08614.11 KFP21994.1 - 0.023 14.9 23.3 0.12 12.6 23.3 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KFP21994.1 - 0.029 14.4 25.4 0.097 12.7 11.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 KFP21994.1 - 0.029 14.0 19.1 0.068 12.8 19.1 1.6 1 1 0 1 1 1 0 GrpE OmpH PF03938.14 KFP21994.1 - 0.031 14.6 25.2 0.1 13.0 25.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RACo_linker PF17650.1 KFP21994.1 - 0.063 13.2 1.1 0.38 10.6 0.1 2.3 1 1 1 2 2 2 0 RACo linker region PuR_N PF09182.10 KFP21994.1 - 0.069 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal CENP-F_leu_zip PF10473.9 KFP21994.1 - 0.071 13.1 23.3 0.09 12.8 23.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HGD-D PF06050.13 KFP21994.1 - 0.1 12.3 1.7 0.1 12.3 1.7 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component HIP1_clath_bdg PF16515.5 KFP21994.1 - 0.1 13.2 22.5 0.098 13.3 10.6 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 KFP21994.1 - 0.13 10.1 14.0 0.15 10.0 14.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KFP21994.1 - 0.18 11.9 21.4 0.2 11.7 21.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4825 PF16107.5 KFP21994.1 - 0.24 11.6 3.2 0.41 10.8 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4825) DUF4407 PF14362.6 KFP21994.1 - 0.24 10.7 12.4 0.27 10.5 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CREPT PF16566.5 KFP21994.1 - 0.25 11.5 14.3 0.096 12.9 11.5 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FlaC_arch PF05377.11 KFP21994.1 - 0.28 11.6 17.1 1.5 9.3 2.2 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Herpes_UL6 PF01763.16 KFP21994.1 - 0.31 9.5 9.4 0.36 9.3 9.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Exonuc_VII_L PF02601.15 KFP21994.1 - 0.44 10.1 14.4 0.51 9.9 14.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 KFP21994.1 - 0.49 8.9 3.4 0.51 8.8 3.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF848 PF05852.11 KFP21994.1 - 0.56 10.3 13.0 2 8.5 12.5 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) UPF0231 PF06062.11 KFP21994.1 - 0.7 10.2 12.6 1.2 9.4 6.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Bacillus_HBL PF05791.11 KFP21994.1 - 0.78 9.5 16.1 0.3 10.9 9.6 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tropomyosin_1 PF12718.7 KFP21994.1 - 0.8 9.9 24.9 1.8 8.7 24.9 1.6 1 1 0 1 1 1 0 Tropomyosin like Uso1_p115_C PF04871.13 KFP21994.1 - 0.89 9.9 24.1 0.49 10.8 19.1 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 KFP21994.1 - 1 9.9 25.4 6.6 7.3 25.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 KFP21994.1 - 1.1 7.8 14.8 1.3 7.5 14.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A 5_nucleotid PF05761.14 KFP21994.1 - 1.3 7.8 10.5 1.4 7.8 10.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family ADIP PF11559.8 KFP21994.1 - 1.5 8.9 25.9 2.3 8.3 20.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 KFP21994.1 - 1.6 6.6 10.6 1.9 6.3 10.6 1.1 1 0 0 1 1 1 0 Prominin DUF2205 PF10224.9 KFP21994.1 - 1.6 8.8 16.6 0.79 9.8 12.2 2.4 1 1 0 2 2 2 0 Short coiled-coil protein YlqD PF11068.8 KFP21994.1 - 1.7 9.1 23.5 1.2e+02 3.1 23.4 2.1 1 1 0 1 1 1 0 YlqD protein DivIC PF04977.15 KFP21994.1 - 2.1 8.2 26.7 2.5 8.0 7.8 3.1 1 1 2 3 3 3 0 Septum formation initiator Calici_MSP PF05752.11 KFP21994.1 - 2.2 8.1 5.7 1.6 8.6 3.9 1.6 1 1 1 2 2 2 0 Calicivirus minor structural protein Macoilin PF09726.9 KFP21994.1 - 2.3 6.7 16.7 3.2 6.2 16.7 1.3 1 0 0 1 1 1 0 Macoilin family BRE1 PF08647.11 KFP21994.1 - 2.4 8.3 25.3 8.1 6.6 19.0 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase bZIP_1 PF00170.21 KFP21994.1 - 2.5 8.3 23.3 2 8.6 7.1 3.1 2 1 1 3 3 3 0 bZIP transcription factor Atg14 PF10186.9 KFP21994.1 - 3.3 6.7 19.0 5.1 6.1 19.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 KFP21994.1 - 3.8 7.9 17.9 7.4 6.9 6.1 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3573 PF12097.8 KFP21994.1 - 3.9 6.2 4.9 4.5 6.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CASP_C PF08172.12 KFP21994.1 - 4.4 6.6 17.1 4.2 6.6 12.6 2.3 1 1 1 2 2 2 0 CASP C terminal Fib_alpha PF08702.10 KFP21994.1 - 4.8 7.4 17.9 9.1 6.5 17.9 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KFP21994.1 - 5.1 7.2 14.6 3.1 7.9 9.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-H PF05837.12 KFP21994.1 - 5.5 7.4 22.4 6 7.3 9.6 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LPP PF04728.13 KFP21994.1 - 6.3 7.3 16.3 21 5.6 1.5 2.8 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Ax_dynein_light PF10211.9 KFP21994.1 - 6.6 6.6 24.2 0.12 12.3 14.0 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain YabA PF06156.13 KFP21994.1 - 6.6 7.4 18.0 18 6.1 7.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA LMBR1 PF04791.16 KFP21994.1 - 7.4 5.3 10.3 8.2 5.2 10.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HemX PF04375.14 KFP21994.1 - 7.5 5.7 23.6 7.8 5.7 14.4 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase NPV_P10 PF05531.12 KFP21994.1 - 7.7 7.1 12.2 1.3 9.6 4.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein End3 PF12761.7 KFP21994.1 - 7.9 6.6 21.3 17 5.5 21.3 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Goodbye PF17109.5 KFP21994.1 - 8.6 6.8 8.1 3.4 8.1 5.2 1.9 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain CENP-Q PF13094.6 KFP21994.1 - 9.3 6.4 21.7 26 5.0 21.7 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_2 PF07716.15 KFP21994.1 - 9.9 6.3 25.4 4.6 7.4 2.9 3.1 3 0 0 3 3 3 0 Basic region leucine zipper Filament PF00038.21 KFP21995.1 - 0.0037 16.9 17.1 0.0068 16.0 6.5 2.0 1 1 1 2 2 2 1 Intermediate filament protein Baculo_PEP_C PF04513.12 KFP21995.1 - 0.0052 16.8 4.0 0.055 13.5 0.5 1.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.16 KFP21995.1 - 0.012 15.8 13.9 0.085 13.1 13.4 2.1 1 1 0 1 1 1 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.9 KFP21995.1 - 0.012 15.6 25.0 0.028 14.5 20.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KFP21995.1 - 0.02 14.5 22.6 0.037 13.7 12.7 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 KFP21995.1 - 0.023 15.1 1.7 0.023 15.1 1.7 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Rab5-bind PF09311.11 KFP21995.1 - 0.03 13.7 17.0 0.023 14.1 12.2 1.9 1 1 1 2 2 2 0 Rabaptin-like protein OmpH PF03938.14 KFP21995.1 - 0.048 14.0 13.9 0.063 13.6 13.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cep57_MT_bd PF06657.13 KFP21995.1 - 0.049 14.1 16.2 1.4 9.4 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 KFP21995.1 - 0.06 12.2 20.6 0.11 11.3 20.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein MIP-T3_C PF17749.1 KFP21995.1 - 0.064 13.2 12.1 0.2 11.6 12.1 1.8 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Spectrin PF00435.21 KFP21995.1 - 0.069 13.6 15.7 0.22 12.0 3.8 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF3584 PF12128.8 KFP21995.1 - 0.069 10.7 14.3 0.08 10.4 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tektin PF03148.14 KFP21995.1 - 0.092 11.5 18.0 0.11 11.2 18.0 1.1 1 0 0 1 1 1 0 Tektin family DUF1664 PF07889.12 KFP21995.1 - 0.11 12.6 9.2 0.14 12.2 7.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CREPT PF16566.5 KFP21995.1 - 0.22 11.7 16.8 0.69 10.1 5.2 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TPR_MLP1_2 PF07926.12 KFP21995.1 - 0.22 11.6 21.5 0.26 11.3 9.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 KFP21995.1 - 0.32 11.6 10.6 9.1 6.9 10.6 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 KFP21995.1 - 0.35 11.0 21.6 0.25 11.4 9.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 KFP21995.1 - 0.37 10.7 20.8 0.055 13.4 12.7 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain ADIP PF11559.8 KFP21995.1 - 0.37 10.9 19.4 0.03 14.4 9.8 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding KNOX2 PF03791.13 KFP21995.1 - 0.42 10.2 0.0 0.42 10.2 0.0 2.7 2 1 1 3 3 3 0 KNOX2 domain FliD_N PF02465.18 KFP21995.1 - 0.42 11.3 9.6 0.045 14.5 2.4 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF16 PF01519.16 KFP21995.1 - 0.48 10.9 10.5 1.4 9.5 10.4 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 TFIID_NTD2 PF04494.15 KFP21995.1 - 0.49 10.6 6.1 0.56 10.4 5.7 1.3 1 1 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain DUF1640 PF07798.11 KFP21995.1 - 0.51 10.4 16.2 0.65 10.0 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Exonuc_VII_L PF02601.15 KFP21995.1 - 0.54 9.8 12.1 0.63 9.6 12.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF848 PF05852.11 KFP21995.1 - 0.55 10.3 11.5 1.2 9.2 11.5 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF641 PF04859.12 KFP21995.1 - 0.56 10.5 17.4 0.18 12.1 9.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF812 PF05667.11 KFP21995.1 - 0.57 9.0 17.3 0.75 8.6 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Mit_KHE1 PF10173.9 KFP21995.1 - 0.69 10.0 6.8 0.82 9.7 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RBD-FIP PF09457.10 KFP21995.1 - 0.76 9.7 7.3 0.31 11.0 1.5 2.6 3 0 0 3 3 3 0 FIP domain ArlS_N PF18719.1 KFP21995.1 - 0.92 9.7 12.9 1.9 8.7 1.6 2.1 1 1 1 2 2 2 0 ArlS sensor domain ParB PF08775.10 KFP21995.1 - 0.94 10.0 9.0 0.35 11.4 5.1 1.8 1 1 1 2 2 2 0 ParB family AAA_32 PF13654.6 KFP21995.1 - 0.99 8.1 12.2 1.2 7.9 12.2 1.1 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 KFP21995.1 - 1.2 8.4 13.9 0.26 10.6 10.2 1.6 1 1 0 1 1 1 0 FAM76 protein Tweety PF04906.13 KFP21995.1 - 1.5 7.4 4.0 1.7 7.2 4.0 1.2 1 0 0 1 1 1 0 Tweety DivIC PF04977.15 KFP21995.1 - 1.7 8.5 14.0 1.2 8.9 1.7 2.6 1 1 2 3 3 3 0 Septum formation initiator Prominin PF05478.11 KFP21995.1 - 1.7 6.5 9.4 2.2 6.1 9.4 1.2 1 0 0 1 1 1 0 Prominin BST2 PF16716.5 KFP21995.1 - 1.9 9.1 18.8 1.8 9.2 5.7 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF3450 PF11932.8 KFP21995.1 - 1.9 7.7 14.0 5.5 6.2 14.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 KFP21995.1 - 2 9.1 21.2 2 9.1 8.6 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 KFP21995.1 - 2 9.1 10.6 0.87 10.3 0.6 2.3 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 KFP21995.1 - 2.3 7.5 8.6 3.3 7.0 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 KFP21995.1 - 2.7 8.4 15.7 5.2 7.6 1.5 2.6 1 1 0 2 2 2 0 Snapin/Pallidin ApoO PF09769.9 KFP21995.1 - 2.8 7.9 4.3 10 6.1 1.2 2.0 1 1 1 2 2 2 0 Apolipoprotein O VPS38 PF17649.1 KFP21995.1 - 2.9 6.7 13.7 0.55 9.0 8.3 1.8 1 1 1 2 2 2 0 Vacuolar protein sorting 38 Mt_ATP-synt_D PF05873.12 KFP21995.1 - 4.5 7.1 13.0 1.5 8.6 3.1 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF724 PF05266.14 KFP21995.1 - 5.2 6.8 17.2 9.6 6.0 17.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DDHD PF02862.17 KFP21995.1 - 5.8 7.0 6.6 7.2 6.7 6.6 1.1 1 0 0 1 1 1 0 DDHD domain YlqD PF11068.8 KFP21995.1 - 6.7 7.1 14.4 4.7 7.6 11.9 1.7 1 1 1 2 2 2 0 YlqD protein APG6_N PF17675.1 KFP21995.1 - 7.5 7.1 24.4 7.3 7.1 10.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_11 PF13086.6 KFP21995.1 - 8.4 6.1 11.8 13 5.5 11.8 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 KFP21995.1 - 8.5 4.2 11.3 10 3.9 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_C_Rb_bdg PF10490.9 KFP21996.1 - 4.4e-21 74.1 0.1 7.9e-21 73.2 0.1 1.4 1 0 0 1 1 1 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 CCDC24 PF15669.5 KFP21996.1 - 0.044 13.7 6.5 0.027 14.3 4.6 1.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Ribosomal_L44 PF00935.19 KFP21996.1 - 1 9.9 4.2 0.64 10.5 1.6 1.9 2 0 0 2 2 2 0 Ribosomal protein L44 Atg14 PF10186.9 KFP21996.1 - 2.3 7.2 12.4 0.43 9.6 3.8 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KFP21996.1 - 3.6 5.4 8.2 3.7 5.3 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 KFP21996.1 - 4.9 6.3 5.2 0.95 8.6 1.7 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter Ion_trans_2 PF07885.16 KFP21997.1 - 4.2e-38 129.2 29.4 5e-20 71.3 11.1 3.9 3 1 1 4 4 4 3 Ion channel DUF872 PF05915.12 KFP21997.1 - 0.17 12.1 2.1 1.1 9.4 0.5 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4079 PF13301.6 KFP21997.1 - 0.18 12.0 1.7 0.39 10.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF5432 PF17497.2 KFP21997.1 - 0.19 11.8 1.6 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5432) SLATT_3 PF18184.1 KFP21997.1 - 0.32 11.1 1.2 0.97 9.6 0.0 2.3 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 CoA_binding_3 PF13727.6 KFP21997.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.4 3 0 0 3 3 3 0 CoA-binding domain Cadherin PF00028.17 KFP21998.1 - 2.9e-76 252.0 9.3 2.3e-16 60.0 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP21998.1 - 5.1e-52 176.1 3.7 1.2e-51 174.8 0.9 2.7 3 0 0 3 3 3 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP21998.1 - 1e-07 31.6 0.0 1 9.2 0.0 4.5 4 1 0 4 4 4 3 Cadherin-like Phage_holin_3_6 PF07332.11 KFP21998.1 - 0.012 15.6 0.2 0.026 14.5 0.2 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2663 PF10864.8 KFP21998.1 - 0.022 15.2 1.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Transp_cyt_pur PF02133.15 KFP21998.1 - 0.042 12.6 0.1 0.065 12.0 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Cadherin_4 PF17803.1 KFP21998.1 - 0.05 14.2 16.0 0.14 12.8 0.8 5.0 5 1 0 5 5 5 0 Bacterial cadherin-like domain Chitin_synth_1N PF08407.11 KFP21998.1 - 0.075 13.0 0.3 3.3 7.7 0.1 3.0 3 0 0 3 3 3 0 Chitin synthase N-terminal Herpes_UL82_83 PF05784.11 KFP21998.1 - 0.085 11.7 0.2 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus DUF3522 PF12036.8 KFP21998.1 - 0.086 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Invasin_D3 PF09134.10 KFP21998.1 - 6 7.2 8.6 43 4.5 0.0 4.7 6 0 0 6 6 6 0 Invasin, domain 3 Cadherin PF00028.17 KFP22003.1 - 1.8e-85 281.5 8.2 7.6e-20 71.2 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP22003.1 - 1.2e-55 187.8 0.1 2.3e-55 186.9 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP22003.1 - 2.8e-06 27.1 0.0 0.96 9.3 0.0 4.6 4 1 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KFP22003.1 - 3e-05 24.0 5.4 0.82 9.7 0.1 5.0 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 KFP22003.1 - 0.1 12.9 0.0 6.5 7.1 0.0 2.8 2 0 0 2 2 2 0 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KFP22003.1 - 2.7 8.7 18.8 3 8.5 0.4 4.5 4 0 0 4 4 4 0 Bacterial cadherin-like domain Invasin_D3 PF09134.10 KFP22003.1 - 6.9 7.1 9.2 24 5.3 0.5 4.4 3 1 0 4 4 4 0 Invasin, domain 3 RVT_1 PF00078.27 KFP22004.1 - 0.082 12.4 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 KFP22008.1 - 1.9e-37 129.0 38.5 8.2e-36 123.7 38.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22008.1 - 1.9e-13 50.8 28.1 1.9e-11 44.2 23.3 2.9 1 1 1 2 2 2 2 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP22008.1 - 5.7e-10 39.0 39.3 8.2e-10 38.5 39.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22008.1 - 0.00086 19.0 28.2 0.00086 19.0 28.2 2.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Pox_MCEL PF03291.16 KFP22009.1 - 4.4e-114 381.1 2.4 5.3e-114 380.8 2.4 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KFP22009.1 - 9.9e-12 45.4 0.0 2.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP22009.1 - 3.3e-11 43.2 0.1 5.9e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP22009.1 - 1.9e-08 34.9 0.0 4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP22009.1 - 1.3e-06 28.3 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFP22009.1 - 2.4e-06 28.2 0.0 4.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFP22009.1 - 0.004 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFP22009.1 - 0.012 15.5 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 KFP22009.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.14 KFP22009.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain DUF1279 PF06916.13 KFP22010.1 - 3.4e-24 85.2 0.4 6.8e-24 84.2 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) YtxH PF12732.7 KFP22010.1 - 0.0013 19.2 1.4 0.0013 19.2 1.4 1.6 2 0 0 2 2 2 1 YtxH-like protein LEA_4 PF02987.16 KFP22010.1 - 0.0038 17.3 8.0 0.0073 16.4 8.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.18 KFP22010.1 - 0.012 15.5 0.2 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Herpes_UL36 PF03586.13 KFP22010.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein HTH_39 PF14090.6 KFP22010.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain m04gp34like PF12216.8 KFP22011.1 - 0.11 12.1 0.9 0.23 11.0 0.6 1.6 2 0 0 2 2 2 0 Immune evasion protein Shisa PF13908.6 KFP22011.1 - 0.13 12.5 0.1 0.13 12.5 0.1 1.8 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PspB PF06667.12 KFP22011.1 - 0.2 11.8 0.3 0.32 11.1 0.3 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF4834 PF16118.5 KFP22011.1 - 0.2 12.6 1.1 0.37 11.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ASH PF15780.5 KFP22013.1 - 2.5e-19 69.3 5.9 4.4e-05 23.6 0.1 8.3 7 1 0 7 7 7 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KFP22013.1 - 1.1e-14 54.4 2.4 0.0042 17.3 0.0 6.6 6 1 0 6 6 6 4 Transmembrane protein 131-like Motile_Sperm PF00635.26 KFP22013.1 - 4e-10 39.5 0.1 0.011 15.5 0.0 5.5 5 0 0 5 5 5 2 MSP (Major sperm protein) domain MYCBPAP PF14646.6 KFP22013.1 - 3.2e-08 33.0 0.0 0.00093 18.2 0.0 4.2 4 0 0 4 4 4 2 MYCBP-associated protein family DUF1573 PF07610.11 KFP22013.1 - 0.0043 17.0 0.2 2.3 8.3 0.0 4.1 4 1 0 4 4 4 1 Protein of unknown function (DUF1573) Transglut_C PF00927.22 KFP22013.1 - 0.13 12.4 0.1 63 3.8 0.0 4.3 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain Spt46 PF17734.1 KFP22015.1 - 5 6.8 7.9 3.4 7.4 0.9 2.7 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 WD40 PF00400.32 KFP22016.1 - 4.6e-10 39.9 23.7 0.00017 22.3 1.9 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP22016.1 - 8.1e-07 29.3 1.8 0.021 15.1 0.3 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP22016.1 - 0.00023 20.3 0.2 0.24 10.3 0.0 2.8 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein RVT_1 PF00078.27 KFP22017.1 - 6.9e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KFP22017.1 - 1e-05 25.5 0.1 2.3e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Y_phosphatase PF00102.27 KFP22018.1 - 3e-77 259.4 0.1 4.6e-77 258.7 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP22018.1 - 0.0012 18.6 1.1 0.022 14.6 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PAC2 PF09754.9 KFP22019.1 - 5.7e-40 137.6 0.0 6.7e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family KIND PF16474.5 KFP22020.1 - 1.7e-46 158.6 2.1 3.4e-46 157.6 0.6 2.2 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain FYVE PF01363.21 KFP22020.1 - 0.14 12.3 14.8 0.37 11.0 14.8 1.7 1 1 0 1 1 1 0 FYVE zinc finger PRELI PF04707.14 KFP22021.1 - 4e-54 182.7 0.0 4.7e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family PDGLE PF13190.6 KFP22021.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 PDGLE domain Baculo_F PF12259.8 KFP22021.1 - 0.089 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein Rep_2 PF01719.17 KFP22021.1 - 0.093 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication protein Peptidase_M41 PF01434.18 KFP22023.1 - 5.3e-66 222.1 0.0 8e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFP22023.1 - 2.1e-42 144.7 0.0 4.4e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP22023.1 - 1.5e-15 56.7 0.1 4.1e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KFP22023.1 - 9.9e-11 42.0 0.2 3.6e-10 40.2 0.2 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 KFP22023.1 - 0.00015 22.1 0.0 0.061 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFP22023.1 - 0.00087 19.3 0.0 0.0038 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFP22023.1 - 0.0015 18.6 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFP22023.1 - 0.0022 18.4 0.3 0.14 12.6 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFP22023.1 - 0.0033 17.2 0.0 0.013 15.2 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFP22023.1 - 0.0059 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFP22023.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFP22023.1 - 0.041 14.1 0.2 0.41 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KFP22023.1 - 0.086 12.2 0.3 0.28 10.5 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFP22023.1 - 0.1 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFP22023.1 - 0.21 11.0 0.5 0.64 9.4 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein Tubulin PF00091.25 KFP22024.1 - 2.1e-60 204.3 0.0 3.7e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFP22024.1 - 5.1e-42 143.0 0.1 8.7e-42 142.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFP22024.1 - 0.0093 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KFP22024.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin like CIDE-N PF02017.15 KFP22025.1 - 3.2e-30 104.0 0.1 9.5e-30 102.5 0.0 1.8 2 0 0 2 2 2 1 CIDE-N domain GCV_T PF01571.21 KFP22025.1 - 0.061 12.7 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Inositol_P PF00459.25 KFP22026.1 - 7.6e-77 258.5 0.1 8.5e-77 258.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TMF_DNA_bd PF12329.8 KFP22027.1 - 0.0002 21.3 25.7 0.0056 16.7 7.2 2.8 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KFP22027.1 - 0.00075 19.7 13.5 0.021 15.1 3.8 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KFP22027.1 - 0.004 16.9 2.4 0.004 16.9 2.4 3.3 2 2 2 4 4 4 1 Septum formation initiator GAS PF13851.6 KFP22027.1 - 0.0045 16.4 19.1 0.094 12.1 7.6 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KFP22027.1 - 0.0064 17.4 11.2 0.0064 17.4 11.2 2.1 1 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Mod_r PF07200.13 KFP22027.1 - 0.0066 16.6 13.1 0.018 15.2 3.0 2.1 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Vmethyltransf_C PF08456.10 KFP22027.1 - 0.012 15.2 4.1 0.015 14.9 4.1 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF4047 PF13256.6 KFP22027.1 - 0.019 15.2 1.4 0.019 15.2 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Jnk-SapK_ap_N PF09744.9 KFP22027.1 - 0.025 14.8 8.3 0.025 14.8 8.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KFP22027.1 - 0.033 14.2 18.3 0.16 12.0 3.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MetOD2 PF18548.1 KFP22027.1 - 0.038 14.1 3.5 0.038 14.1 3.5 2.6 2 1 0 2 2 2 0 Metanogen output domain 2 Arc_PepC_II PF06847.11 KFP22027.1 - 0.053 14.0 4.0 2.9 8.5 0.1 2.5 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Ribosomal_L34e PF01199.18 KFP22027.1 - 0.055 13.8 1.8 0.11 12.8 1.3 1.8 2 0 0 2 2 1 0 Ribosomal protein L34e DUF4140 PF13600.6 KFP22027.1 - 0.069 13.6 9.0 0.78 10.2 0.1 2.5 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) TFR_dimer PF04253.15 KFP22027.1 - 0.1 12.7 1.0 0.89 9.7 0.1 2.1 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Exonuc_VII_L PF02601.15 KFP22027.1 - 0.12 11.9 6.9 0.16 11.5 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KFP22027.1 - 0.15 11.4 11.2 0.61 9.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KFP22027.1 - 0.21 12.1 23.5 0.47 11.0 10.9 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF3452 PF11934.8 KFP22027.1 - 0.22 11.1 3.5 0.24 10.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Cnn_1N PF07989.11 KFP22027.1 - 0.22 11.7 19.2 0.78 9.9 2.6 3.0 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 KFP22027.1 - 0.23 10.3 22.3 0.11 11.3 7.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KFP22027.1 - 0.23 11.5 15.9 0.88 9.6 3.8 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 KFP22027.1 - 0.25 10.2 17.1 0.18 10.6 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 KFP22027.1 - 0.26 11.7 5.1 1.1 9.6 1.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 KFP22027.1 - 0.27 11.3 7.1 2.6 8.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 KFP22027.1 - 0.27 11.9 17.1 0.17 12.5 4.5 2.6 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 NCKAP5 PF15246.6 KFP22027.1 - 0.27 10.8 11.2 0.06 12.9 6.8 1.8 1 1 1 2 2 2 0 Nck-associated protein 5, Peripheral clock protein ZapB PF06005.12 KFP22027.1 - 0.29 11.6 25.5 0.85 10.1 9.5 2.7 2 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KFP22027.1 - 0.3 11.7 13.4 0.75 10.5 5.6 2.4 2 1 0 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 KFP22027.1 - 0.3 11.4 15.2 0.17 12.2 2.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 KFP22027.1 - 0.34 10.8 18.0 0.96 9.4 3.6 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain LMBR1 PF04791.16 KFP22027.1 - 0.34 9.8 8.4 0.44 9.4 8.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 KFP22027.1 - 0.38 10.9 15.7 0.19 11.9 2.6 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 KFP22027.1 - 0.4 10.1 18.3 0.73 9.2 18.3 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc24 PF08286.11 KFP22027.1 - 0.47 10.7 14.5 0.85 9.9 2.8 2.4 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Spc29 PF17082.5 KFP22027.1 - 0.5 10.2 10.6 1.9 8.3 2.4 2.1 1 1 0 2 2 2 0 Spindle Pole Component 29 CCDC-167 PF15188.6 KFP22027.1 - 0.69 10.3 14.7 0.3 11.4 8.7 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 CENP-H PF05837.12 KFP22027.1 - 0.69 10.3 14.1 1.9 8.9 2.3 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2046 PF09755.9 KFP22027.1 - 0.7 9.1 20.1 0.34 10.1 5.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Ubiquitin_4 PF18036.1 KFP22027.1 - 0.8 9.8 9.0 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-like domain DUF1319 PF07028.11 KFP22027.1 - 0.85 9.9 9.1 1.9 8.8 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF4407 PF14362.6 KFP22027.1 - 0.94 8.8 8.7 1.4 8.2 8.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2935 PF11155.8 KFP22027.1 - 0.99 9.8 7.5 0.7 10.2 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) TPR_MLP1_2 PF07926.12 KFP22027.1 - 1.1 9.3 17.6 1.2 9.2 5.2 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nmad5 PF18757.1 KFP22027.1 - 1.2 9.3 8.2 0.66 10.2 5.5 1.9 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 Leu_zip PF15294.6 KFP22027.1 - 1.5 8.3 17.5 0.1 12.1 6.3 2.1 1 1 0 2 2 2 0 Leucine zipper Vps51 PF08700.11 KFP22027.1 - 1.7 8.8 9.8 3.4 7.8 1.0 3.0 3 1 0 3 3 2 0 Vps51/Vps67 Bacillus_HBL PF05791.11 KFP22027.1 - 1.7 8.4 10.1 0.76 9.6 1.6 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BRE1 PF08647.11 KFP22027.1 - 2 8.6 19.7 0.56 10.3 5.8 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Filament PF00038.21 KFP22027.1 - 2 7.9 18.5 0.82 9.2 4.9 2.2 1 1 1 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.21 KFP22027.1 - 2.2 8.4 19.4 0.45 10.7 4.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor CIAPIN1 PF05093.13 KFP22027.1 - 2.9 8.4 6.6 10 6.7 0.4 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TSC22 PF01166.18 KFP22027.1 - 3 8.2 16.0 11 6.4 2.3 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family HemX PF04375.14 KFP22027.1 - 3 7.0 8.4 3.8 6.7 2.4 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Herpes_UL6 PF01763.16 KFP22027.1 - 3.4 6.1 12.9 0.084 11.4 2.2 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like NRBF2 PF08961.10 KFP22027.1 - 4 7.0 14.0 0.13 11.8 4.9 2.1 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4446 PF14584.6 KFP22027.1 - 4.1 7.4 13.9 3.8 7.5 2.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Uds1 PF15456.6 KFP22027.1 - 4.2 7.6 16.2 5.2 7.2 1.2 3.0 3 0 0 3 3 3 0 Up-regulated During Septation DUF2205 PF10224.9 KFP22027.1 - 4.3 7.4 16.5 0.68 10.0 2.5 2.6 2 1 1 3 3 2 0 Short coiled-coil protein GIT_CC PF16559.5 KFP22027.1 - 4.5 7.2 9.5 1.6 8.7 0.1 2.9 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF848 PF05852.11 KFP22027.1 - 4.7 7.3 15.1 4 7.6 4.6 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4094 PF13334.6 KFP22027.1 - 5 7.6 7.9 5.2 7.6 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) IpaC_SipC PF09599.10 KFP22027.1 - 5.1 6.5 8.0 14 5.1 5.0 1.9 1 1 1 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) LepB_GAP_N PF18172.1 KFP22027.1 - 6 6.7 9.1 3 7.7 0.7 2.1 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain Seryl_tRNA_N PF02403.22 KFP22027.1 - 6.1 7.1 18.6 3.8 7.8 7.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DHR10 PF18595.1 KFP22027.1 - 6.6 6.8 22.9 2.1 8.5 7.7 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KFP22027.1 - 7.2 6.8 13.9 9.1 6.5 4.0 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 KFP22027.1 - 9.8 6.6 24.3 6.6 7.2 7.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Metallophos PF00149.28 KFP22028.1 - 6.3e-11 43.2 0.3 2.3e-10 41.3 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFP22028.1 - 0.00031 21.0 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain G-alpha PF00503.20 KFP22029.1 - 1.8e-103 346.4 0.9 2.1e-103 346.2 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFP22029.1 - 3.3e-14 52.7 1.0 6.8e-13 48.4 0.4 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP22029.1 - 8.5e-05 22.2 0.0 0.085 12.4 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KFP22029.1 - 0.00041 20.6 0.8 0.12 12.6 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KFP22029.1 - 0.0017 17.7 2.2 0.0029 17.0 0.2 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SNAP PF14938.6 KFP22031.1 - 2.3e-26 92.9 9.8 3.2e-26 92.4 9.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KFP22031.1 - 3.4e-06 26.7 9.2 0.0001 21.8 7.5 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KFP22031.1 - 2.2e-05 24.7 14.3 0.0017 18.6 4.6 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22031.1 - 0.0031 17.6 4.1 4.3 7.8 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22031.1 - 0.011 15.6 6.8 16 5.5 0.3 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat UPF0449 PF15136.6 KFP22031.1 - 0.012 16.1 2.6 0.83 10.2 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TPR_14 PF13428.6 KFP22031.1 - 0.023 15.5 13.7 2.8 9.0 1.9 5.4 2 1 4 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 KFP22031.1 - 0.067 13.9 14.1 1.2 10.2 0.5 5.6 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat DUF2150 PF09920.9 KFP22031.1 - 0.14 12.2 1.4 0.27 11.2 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_2 PF07719.17 KFP22031.1 - 0.22 11.7 16.5 4 7.8 0.1 6.5 3 2 6 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.7 KFP22031.1 - 0.23 11.7 3.9 0.24 11.7 0.4 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat Sel1 PF08238.12 KFP22031.1 - 0.96 10.2 0.1 0.96 10.2 0.1 3.1 3 1 1 4 4 3 0 Sel1 repeat TPR_19 PF14559.6 KFP22031.1 - 1.4 9.5 14.8 2.7 8.6 0.8 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat MCD_N PF17408.2 KFP22031.1 - 1.7 8.8 4.0 19 5.4 0.3 2.9 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain TPR_10 PF13374.6 KFP22031.1 - 5.3 7.1 15.1 1.2 9.1 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat APCDDC PF14921.6 KFP22034.1 - 2.7e-129 429.6 6.9 1.8e-103 345.0 2.3 2.4 2 1 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 CFC PF09443.10 KFP22034.1 - 4.7 7.2 6.9 2.1 8.2 0.1 2.9 3 0 0 3 3 3 0 Cripto_Frl-1_Cryptic (CFC) Motile_Sperm PF00635.26 KFP22035.1 - 1.6e-30 105.2 0.1 2.6e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain YabA PF06156.13 KFP22035.1 - 0.012 16.3 0.1 0.023 15.3 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ASH PF15780.5 KFP22035.1 - 0.02 15.1 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ZapB PF06005.12 KFP22035.1 - 0.061 13.8 0.1 0.099 13.1 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB GIT_CC PF16559.5 KFP22035.1 - 0.066 13.1 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 KFP22035.1 - 0.1 12.7 1.0 0.2 11.8 1.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Ras PF00071.22 KFP22036.1 - 9.7e-53 178.1 0.0 1.1e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22036.1 - 1e-31 109.7 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22036.1 - 7.8e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFP22036.1 - 0.0005 20.0 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFP22036.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP22036.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase MCR_beta PF02241.18 KFP22036.1 - 0.13 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain HEAT PF02985.22 KFP22038.1 - 7.8e-27 91.0 15.3 5.3e-05 23.1 0.3 9.3 8 0 0 8 8 8 6 HEAT repeat HEAT_2 PF13646.6 KFP22038.1 - 1.3e-11 44.7 2.8 0.0054 17.1 0.0 6.4 5 3 3 8 8 8 4 HEAT repeats Cnd1 PF12717.7 KFP22038.1 - 1.1e-07 32.0 6.2 0.02 14.9 0.4 5.5 6 0 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 WRNPLPNID PF15017.6 KFP22038.1 - 5.6e-06 27.1 0.5 5.6e-06 27.1 0.5 2.5 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box DNA_alkylation PF08713.11 KFP22038.1 - 0.094 12.4 0.0 19 4.9 0.0 2.9 2 0 0 2 2 2 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 KFP22038.1 - 0.17 12.5 8.9 8.1 7.1 0.1 5.7 5 2 0 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFP22038.1 - 4.4 7.9 6.6 7.8 7.1 0.0 4.8 7 0 0 7 7 7 0 HEAT-like repeat RhoGAP PF00620.27 KFP22040.1 - 7.5e-44 149.2 0.3 7.5e-44 149.2 0.3 3.1 2 1 0 3 3 3 2 RhoGAP domain Nod1 PF17114.5 KFP22040.1 - 0.17 12.1 5.4 0.08 13.1 0.6 2.7 2 1 1 3 3 3 0 Gef2-related medial cortical node protein Nod1 Tsg PF04668.12 KFP22041.1 - 9e-46 155.9 6.4 9e-46 155.9 6.4 2.2 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Ank_4 PF13637.6 KFP22042.1 - 1.3e-19 70.2 0.0 1.1e-08 35.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP22042.1 - 1.3e-18 67.4 0.0 3e-12 47.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFP22042.1 - 6.8e-18 64.3 0.1 0.00032 21.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KFP22042.1 - 1.6e-17 63.3 0.1 2.6e-07 30.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP22042.1 - 7.4e-15 53.6 0.0 9.4e-05 22.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat 2Fe-2S_thioredx PF01257.19 KFP22043.1 - 3.9e-66 221.4 0.1 4.6e-66 221.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SOGA PF11365.8 KFP22045.1 - 2.7e-72 240.0 37.4 7.9e-39 132.7 2.1 5.4 3 1 3 6 6 6 3 Protein SOGA TSC22 PF01166.18 KFP22045.1 - 0.0006 20.1 39.3 0.022 15.1 0.3 6.2 6 1 0 6 6 6 4 TSC-22/dip/bun family DUF4201 PF13870.6 KFP22045.1 - 0.87 9.3 0.0 0.87 9.3 0.0 5.9 5 1 2 7 7 7 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 KFP22045.1 - 3.5 6.9 19.3 33 3.7 6.4 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) HTH_12 PF08461.10 KFP22045.1 - 7 6.7 11.9 16 5.5 0.2 4.2 4 0 0 4 4 4 0 Ribonuclease R winged-helix domain Pro_isomerase PF00160.21 KFP22046.1 - 4.7e-40 137.4 0.2 5.2e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD E1_dh PF00676.20 KFP22047.1 - 1.8e-97 325.9 0.0 2.5e-97 325.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KFP22047.1 - 1.9e-52 177.5 0.0 3.5e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain 2-oxogl_dehyd_N PF16078.5 KFP22047.1 - 1.7e-19 69.1 1.0 3e-19 68.3 1.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus GGA_N-GAT PF18308.1 KFP22047.1 - 0.075 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 GGA N-GAT domain Ras PF00071.22 KFP22048.1 - 5.6e-57 191.9 0.0 6.3e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22048.1 - 4.7e-23 81.7 0.0 7.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22048.1 - 3.5e-10 39.6 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP22048.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KFP22049.1 - 5.6e-57 191.9 0.0 6.3e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22049.1 - 4.7e-23 81.7 0.0 7.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22049.1 - 3.5e-10 39.6 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP22049.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Frag1 PF10277.9 KFP22050.1 - 1.3e-06 28.2 0.2 1.3e-06 28.1 0.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Nup96 PF12110.8 KFP22051.1 - 3.3e-99 331.7 2.2 4.6e-99 331.2 2.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KFP22051.1 - 1.3e-47 161.7 0.0 2.1e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KFP22051.1 - 2.7e-06 28.1 197.8 0.0013 19.5 32.7 6.5 2 2 4 6 6 6 4 Nucleoporin FG repeat region IFN-gamma PF00714.17 KFP22052.1 - 1.7e-28 99.2 3.5 2.1e-28 98.9 3.5 1.1 1 0 0 1 1 1 1 Interferon gamma DUF948 PF06103.11 KFP22052.1 - 0.065 13.5 0.4 0.67 10.3 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KFP22052.1 - 0.084 13.1 2.6 0.077 13.2 1.1 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LPP PF04728.13 KFP22052.1 - 0.34 11.3 0.4 0.34 11.3 0.4 2.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper IL10 PF00726.17 KFP22053.1 - 9.9e-09 34.9 0.0 1.6e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Interleukin 10 IL22 PF14565.6 KFP22053.1 - 1.6e-05 25.2 0.0 2.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL22 PF14565.6 KFP22054.1 - 3.8e-76 254.0 3.2 4.4e-76 253.8 3.2 1.0 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.17 KFP22054.1 - 1.4e-06 28.0 0.9 1.6e-06 27.8 0.9 1.1 1 0 0 1 1 1 1 Interleukin 10 CPL PF08144.11 KFP22054.1 - 0.017 15.4 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 CPL (NUC119) domain Nucleolin_bd PF16725.5 KFP22054.1 - 0.088 12.5 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Nucleolin binding domain MDM1 PF15501.6 KFP22055.1 - 6.2e-161 537.3 36.6 3.9e-160 534.7 36.6 2.0 1 1 0 1 1 1 1 Nuclear protein MDM1 KCT2 PF17818.1 KFP22055.1 - 0.053 13.6 2.2 0.17 12.0 2.2 1.8 1 0 0 1 1 1 0 Keratinocyte-associated gene product Ras PF00071.22 KFP22057.1 - 2.2e-57 193.2 0.3 2.5e-57 193.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22057.1 - 7.2e-21 74.6 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22057.1 - 1.1e-08 34.7 0.2 1.2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP22057.1 - 7.2e-05 22.4 0.3 0.00018 21.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFP22057.1 - 0.00066 19.7 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP22057.1 - 0.0022 17.9 2.9 0.57 10.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFP22057.1 - 0.0038 16.5 0.0 0.0059 15.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 KFP22057.1 - 0.25 11.6 1.0 12 6.2 0.5 2.8 2 1 0 2 2 2 0 AAA domain Nup84_Nup100 PF04121.13 KFP22058.1 - 4.8e-210 699.4 19.5 5.7e-210 699.2 19.5 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF2312 PF10073.9 KFP22058.1 - 0.1 12.2 0.1 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TPT PF03151.16 KFP22059.1 - 3.1e-12 46.5 11.8 4.1e-12 46.1 11.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP22059.1 - 7.1e-05 23.0 14.6 7.1e-05 23.0 14.6 2.7 1 1 2 3 3 3 1 EamA-like transporter family CopD PF05425.13 KFP22059.1 - 0.85 10.1 7.0 0.71 10.3 1.6 2.7 3 0 0 3 3 3 0 Copper resistance protein D zf-C3HC4_3 PF13920.6 KFP22060.1 - 2.6e-13 49.6 9.6 2.6e-13 49.6 9.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFP22060.1 - 1.3e-10 41.0 0.1 4.4e-10 39.3 0.1 1.9 1 1 1 2 2 2 1 SWIB/MDM2 domain zf-RanBP PF00641.18 KFP22060.1 - 6.5e-09 35.0 1.9 6.5e-09 35.0 1.9 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_2 PF13639.6 KFP22060.1 - 0.016 15.6 9.5 0.016 15.6 9.5 2.2 2 0 0 2 2 2 0 Ring finger domain Viral_DNA_bp PF00747.17 KFP22060.1 - 0.09 9.9 1.0 3 4.9 0.0 2.0 2 0 0 2 2 2 0 ssDNA binding protein zf-FPG_IleRS PF06827.14 KFP22060.1 - 0.094 12.6 0.1 0.094 12.6 0.1 3.8 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DZR PF12773.7 KFP22060.1 - 0.22 11.6 15.8 0.59 10.2 1.9 3.2 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFP22060.1 - 0.61 9.9 9.3 0.16 11.8 2.4 3.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFP22060.1 - 6.3 6.9 12.3 1 9.4 4.8 2.8 2 0 0 2 2 2 0 zinc-ribbons RRM_1 PF00076.22 KFP22061.1 - 3.9e-07 29.8 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.7 KFP22061.1 - 0.09 13.4 44.1 0.17 12.5 44.1 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term YEATS PF03366.16 KFP22062.1 - 3.8e-27 94.1 0.2 7e-27 93.2 0.2 1.5 1 0 0 1 1 1 1 YEATS family SOGA PF11365.8 KFP22062.1 - 0.0053 17.8 3.0 0.009 17.1 3.0 1.4 1 0 0 1 1 1 1 Protein SOGA FapA PF03961.13 KFP22062.1 - 0.077 11.6 1.4 0.09 11.4 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RIC3 PF15361.6 KFP22062.1 - 0.12 12.8 1.0 0.18 12.2 1.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF1664 PF07889.12 KFP22062.1 - 0.14 12.2 1.1 0.21 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KFP22062.1 - 0.48 10.2 3.0 0.98 9.2 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator IRS PF02174.17 KFP22064.1 - 8.1e-25 86.6 0.1 1.9e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Cpn60_TCP1 PF00118.24 KFP22065.1 - 1.7e-143 478.8 13.8 2e-143 478.6 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2529 PF10740.9 KFP22065.1 - 0.0065 16.1 0.1 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) Ribosomal_S13 PF00416.22 KFP22065.1 - 0.094 13.1 1.4 0.31 11.4 0.3 2.4 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF5442 PF17514.2 KFP22065.1 - 0.15 12.3 0.2 0.31 11.2 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Asp PF00026.23 KFP22066.1 - 7.4e-115 383.7 0.1 8.6e-115 383.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFP22066.1 - 7e-13 49.2 0.8 1.4e-10 41.7 0.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KFP22066.1 - 9e-10 38.2 1.3 1.5e-09 37.5 1.3 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.6 KFP22066.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Bestrophin PF01062.21 KFP22067.1 - 3.8e-108 361.3 5.3 3.8e-108 361.3 5.3 1.4 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel Autophagy_N PF03986.13 KFP22067.1 - 0.0071 16.3 0.5 0.013 15.4 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Sec2p PF06428.11 KFP22068.1 - 1.9e-08 34.2 9.3 1.9e-08 34.2 9.3 2.1 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KFP22068.1 - 0.0037 16.7 3.3 0.0061 15.9 3.3 1.3 1 0 0 1 1 1 1 FAM76 protein T3SSipB PF16535.5 KFP22068.1 - 0.035 14.6 4.6 0.061 13.8 4.6 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB UPF0242 PF06785.11 KFP22068.1 - 0.069 13.3 6.3 0.11 12.6 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KFP22068.1 - 0.087 11.7 8.5 0.14 11.0 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KFP22068.1 - 0.093 10.2 7.9 0.14 9.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GCN5L1 PF06320.13 KFP22068.1 - 0.11 12.7 4.4 0.22 11.7 4.4 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF3987 PF13148.6 KFP22068.1 - 0.15 11.0 2.8 0.22 10.5 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FapA PF03961.13 KFP22068.1 - 0.25 9.9 2.4 0.36 9.4 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 KFP22068.1 - 0.27 10.6 10.3 0.49 9.7 10.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KFP22068.1 - 0.56 10.5 7.9 5.9 7.2 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Cauli_AT PF03233.13 KFP22068.1 - 0.68 9.8 3.7 13 5.7 1.2 2.6 1 1 2 3 3 3 0 Aphid transmission protein TPR_MLP1_2 PF07926.12 KFP22068.1 - 0.77 9.8 14.4 1.8 8.6 14.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KFP22068.1 - 0.83 9.9 11.3 2.9 8.1 11.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CC2-LZ PF16516.5 KFP22068.1 - 1.4 9.4 11.8 1.9 8.9 3.7 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PRKG1_interact PF15898.5 KFP22068.1 - 1.4 9.8 8.8 3.3 8.6 8.8 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KFP22068.1 - 2 8.9 9.5 4.6 7.7 9.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KFP22068.1 - 7 6.8 15.3 3.7 7.7 1.6 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KFP22068.1 - 7.4 5.8 8.2 26 4.0 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MRF_C2 PF13888.6 KFP22070.1 - 7.6e-50 168.4 1.4 2.1e-49 167.0 1.4 1.8 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.12 KFP22070.1 - 4.2e-27 95.6 0.4 8.3e-26 91.3 0.4 2.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.6 KFP22070.1 - 1.8e-21 75.0 0.6 5.2e-21 73.5 0.6 1.8 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.6 KFP22070.1 - 7e-14 51.9 0.1 1.5e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase NOT2_3_5 PF04153.18 KFP22072.1 - 3.2e-32 111.4 0.2 6.1e-32 110.5 0.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Y_phosphatase PF00102.27 KFP22073.1 - 3e-75 252.8 1.0 6.9e-75 251.6 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP22073.1 - 0.00022 21.3 0.0 0.00056 20.0 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KFP22073.1 - 0.00036 20.4 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP22073.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate CyRPA PF18638.1 KFP22073.1 - 0.02 14.1 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain WBP-1 PF11669.8 KFP22073.1 - 0.059 14.0 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3149 PF11346.8 KFP22073.1 - 1.1 9.0 4.1 2.2 8.0 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Tetraspanin PF00335.20 KFP22074.1 - 1.6e-45 155.6 16.2 1.8e-45 155.4 16.2 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 KFP22074.1 - 0.0031 17.5 1.0 0.0031 17.5 1.0 2.2 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 KFP22074.1 - 0.079 12.6 1.8 0.28 10.8 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DASH_Duo1 PF08651.10 KFP22074.1 - 0.15 11.8 0.4 0.32 10.8 0.4 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 LRR_8 PF13855.6 KFP22075.1 - 5e-105 343.3 81.2 2.9e-15 55.8 0.8 8.5 2 2 10 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 KFP22075.1 - 3.3e-41 138.6 38.2 3.4e-06 27.3 0.4 9.7 6 1 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP22075.1 - 2.5e-33 114.7 0.1 1.2e-11 44.7 0.0 5.1 2 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP22075.1 - 3.3e-15 56.0 10.2 0.0062 16.1 0.6 5.4 1 1 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KFP22075.1 - 1.1e-12 46.6 37.3 0.99 10.2 0.0 14.3 13 2 1 14 14 14 4 Leucine Rich Repeat 7tm_1 PF00001.21 KFP22075.1 - 5.6e-12 45.5 16.4 1.2e-11 44.4 16.4 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP22075.1 - 0.00025 20.7 9.6 0.00025 20.7 9.6 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-C3H1 PF10650.9 KFP22077.1 - 6.3e-09 35.4 4.3 1.4e-08 34.3 4.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_17 PF13431.6 KFP22077.1 - 1.2e-05 25.3 6.4 0.78 10.3 0.8 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22077.1 - 4e-05 24.0 6.4 2.5 8.7 0.4 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22077.1 - 0.00065 20.3 9.0 11 7.1 0.0 6.9 7 1 2 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22077.1 - 0.25 11.2 2.7 4.9 7.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22077.1 - 0.4 10.4 6.3 0.59 9.9 0.4 3.6 3 1 1 4 4 4 0 TPR repeat ANAPC3 PF12895.7 KFP22077.1 - 2.1 8.6 5.5 0.81 10.0 0.7 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF92 PF01940.16 KFP22078.1 - 2.5e-77 259.5 3.5 3.7e-77 258.9 3.5 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 Ras PF00071.22 KFP22079.1 - 1.5e-43 148.2 0.1 1.8e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22079.1 - 1.7e-22 79.9 0.1 3.6e-22 78.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22079.1 - 1e-09 38.1 0.1 1.2e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP22079.1 - 0.00013 21.6 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFP22079.1 - 0.003 17.5 0.1 0.0056 16.6 0.1 1.4 1 1 0 1 1 1 1 RsgA GTPase PduV-EutP PF10662.9 KFP22079.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RabGAP-TBC PF00566.18 KFP22081.1 - 4.7e-50 170.2 10.6 7.3e-50 169.6 10.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFP22081.1 - 4.1e-35 120.8 0.5 6.9e-35 120.0 0.5 1.4 1 0 0 1 1 1 1 Rab-binding domain (RBD) Biopterin_H PF00351.21 KFP22082.1 - 3e-175 582.0 0.1 3.6e-175 581.8 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Peptidase_M1 PF01433.20 KFP22083.1 - 6.7e-81 271.0 0.9 1.2e-80 270.2 0.9 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFP22083.1 - 3.1e-77 260.2 3.9 5.5e-77 259.4 3.9 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFP22083.1 - 1e-28 100.8 0.3 1.8e-28 100.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ion_trans PF00520.31 KFP22090.1 - 8.3e-44 149.7 14.6 1e-43 149.3 14.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KFP22090.1 - 2.8e-16 59.6 0.0 7.7e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP22090.1 - 2.7e-11 43.3 2.7 2.7e-11 43.3 2.7 2.7 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 KFP22090.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain IL23 PF16649.5 KFP22090.1 - 0.078 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Interleukin 23 subunit alpha EF-hand_6 PF13405.6 KFP22091.1 - 1.6e-09 36.9 2.4 0.0013 18.5 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KFP22091.1 - 1.9e-07 30.1 3.2 0.00025 20.4 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFP22091.1 - 8.7e-06 26.1 3.2 7.7e-05 23.1 1.1 3.2 2 1 0 2 2 2 1 EF-hand domain pair DUF1126 PF06565.12 KFP22091.1 - 0.00012 21.9 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 DUF1126 PH-like domain EF-hand_5 PF13202.6 KFP22091.1 - 0.034 13.7 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KFP22091.1 - 0.05 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair RIC3 PF15361.6 KFP22092.1 - 2.8e-18 66.7 0.3 3.1e-18 66.6 0.3 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF3611 PF12263.8 KFP22092.1 - 0.22 11.4 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) CAP PF00188.26 KFP22093.1 - 9.7e-17 62.0 6.7 1.6e-16 61.3 6.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFP22094.1 - 6.3e-24 85.2 2.5 7.7e-24 84.9 2.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KFP22095.1 - 7.9e-26 91.4 4.8 1e-25 91.0 4.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_8 PF17903.1 KFP22096.1 - 1.2e-30 105.4 0.0 1.2e-30 105.4 0.0 2.6 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 KFP22096.1 - 0.0001 22.1 1.6 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 KFP22096.1 - 0.053 13.4 0.6 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 KH domain NAP PF00956.18 KFP22097.1 - 7.4e-114 379.5 7.0 7.4e-114 379.5 7.0 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) sCache_3_3 PF17202.4 KFP22097.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 ING PF12998.7 KFP22097.1 - 0.074 13.6 2.2 0.38 11.4 2.2 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RNA_pol_3_Rpc31 PF11705.8 KFP22097.1 - 1.3 9.2 18.4 0.32 11.2 6.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 GEN1_C PF18380.1 KFP22097.1 - 4.9 8.1 12.6 1.9 9.4 3.5 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Cpn60_TCP1 PF00118.24 KFP22098.1 - 4.7e-08 32.1 0.0 0.00049 18.8 0.0 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Oxysterol_BP PF01237.18 KFP22099.1 - 2.2e-95 319.7 4.2 6.5e-93 311.5 4.2 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KFP22099.1 - 2.9e-10 40.6 0.1 9.5e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 PH domain DHHC PF01529.20 KFP22101.1 - 1.8e-35 122.0 20.9 1.8e-35 122.0 20.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KFP22101.1 - 2.6e-32 110.8 6.1 8e-09 35.9 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP22101.1 - 8.2e-31 106.4 0.2 3.6e-16 59.5 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP22101.1 - 7e-29 99.5 2.1 6.5e-07 29.5 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP22101.1 - 1e-28 96.2 1.5 4.5e-05 23.5 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KFP22101.1 - 2.3e-23 81.5 2.3 5.6e-06 26.6 0.4 6.0 6 0 0 6 6 6 5 Ankyrin repeat LIM PF00412.22 KFP22102.1 - 1.7e-30 105.0 27.3 2.7e-17 62.8 5.5 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.6 KFP22102.1 - 0.012 15.5 9.4 0.035 14.0 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf_UBZ PF18439.1 KFP22102.1 - 0.072 12.7 12.7 0.36 10.5 0.5 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_12 PF18658.1 KFP22102.1 - 0.94 9.1 6.0 2.8 7.6 0.8 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type RVT_1 PF00078.27 KFP22103.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) E2F_TDP PF02319.20 KFP22104.1 - 1.5e-42 143.5 1.5 9.2e-21 73.7 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 KFP22104.1 - 0.00016 21.5 0.1 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KFP22104.1 - 0.00084 19.5 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC Cdc6_C PF09079.11 KFP22104.1 - 0.1 12.6 0.0 8 6.5 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain CH PF00307.31 KFP22106.1 - 8.8e-15 54.8 0.7 1.6e-14 54.0 0.1 1.8 2 0 0 2 2 1 1 Calponin homology (CH) domain AAA_14 PF13173.6 KFP22106.1 - 6.8e-06 26.2 0.0 2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFP22106.1 - 1.6e-05 25.3 0.1 5.9e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFP22106.1 - 2.4e-05 24.6 0.2 0.0014 18.9 0.2 3.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFP22106.1 - 4.6e-05 23.9 0.2 0.027 14.9 0.0 3.0 1 1 1 2 2 2 1 AAA ATPase domain CAMSAP_CH PF11971.8 KFP22106.1 - 0.00085 19.1 0.2 0.0083 15.9 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain RNA_helicase PF00910.22 KFP22106.1 - 0.0012 19.2 0.0 0.0059 17.0 0.0 2.3 2 0 0 2 2 1 1 RNA helicase PhoH PF02562.16 KFP22106.1 - 0.0039 16.7 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 KFP22106.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFP22106.1 - 0.005 17.4 0.0 0.026 15.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 KFP22106.1 - 0.0054 16.8 0.2 0.15 12.1 0.1 2.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 KFP22106.1 - 0.0097 15.3 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFP22106.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFP22106.1 - 0.015 14.3 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 KFP22106.1 - 0.019 15.0 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFP22106.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KFP22106.1 - 0.026 14.6 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KFP22106.1 - 0.028 14.0 0.0 0.13 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain CH_2 PF06294.11 KFP22106.1 - 0.031 14.4 0.2 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 CH-like domain in sperm protein AAA_19 PF13245.6 KFP22106.1 - 0.053 13.9 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFP22106.1 - 0.073 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFP22106.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DivIC PF04977.15 KFP22106.1 - 0.13 12.0 10.8 2.2 8.1 0.1 4.3 4 0 0 4 4 4 0 Septum formation initiator DUF4201 PF13870.6 KFP22106.1 - 2.5 7.8 16.8 0.89 9.3 4.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GrpE PF01025.19 KFP22106.1 - 3.8 7.2 9.9 7.9 6.1 0.6 2.9 2 0 0 2 2 2 0 GrpE C2 PF00168.30 KFP22108.1 - 5.9e-55 183.9 0.4 8.8e-27 93.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain Comm PF15957.5 KFP22108.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 Commissureless CEP76-C2 PF15627.6 KFP22108.1 - 0.0022 17.6 0.0 1 8.9 0.0 2.3 1 1 1 2 2 2 2 CEP76 C2 domain Shisa PF13908.6 KFP22108.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MAP17 PF15807.5 KFP22108.1 - 0.03 14.5 0.1 0.074 13.3 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LYRIC PF15686.5 KFP22108.1 - 0.041 13.4 0.0 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family DUF1258 PF06869.12 KFP22108.1 - 0.051 13.0 0.3 0.095 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DOCK-C2 PF14429.6 KFP22108.1 - 0.079 12.8 0.3 7.7 6.3 0.0 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins EphA2_TM PF14575.6 KFP22108.1 - 0.094 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orthopox_F7 PF05813.12 KFP22108.1 - 0.96 9.6 4.5 3.1 8.0 3.9 2.1 2 0 0 2 2 2 0 Orthopoxvirus F7 protein OAD_gamma PF04277.13 KFP22108.1 - 9.4 6.9 7.0 0.49 11.0 0.4 2.4 3 1 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain ATG16 PF08614.11 KFP22109.1 - 2.2e-05 24.8 11.1 2.2e-05 24.8 11.1 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KFP22109.1 - 8.2e-05 22.8 3.2 8.2e-05 22.8 3.2 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF4618 PF15397.6 KFP22109.1 - 0.00044 19.8 1.9 0.00071 19.1 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) FPP PF05911.11 KFP22109.1 - 0.00064 18.1 10.0 0.00064 18.1 10.0 1.4 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KFP22109.1 - 0.0014 18.7 11.1 0.0014 18.7 11.1 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 KFP22109.1 - 0.0015 19.4 10.6 0.0015 19.4 10.6 2.8 2 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 KFP22109.1 - 0.0017 17.8 4.6 0.002 17.5 4.6 1.0 1 0 0 1 1 1 1 FAM76 protein FlxA PF14282.6 KFP22109.1 - 0.0024 17.8 4.1 0.0024 17.8 4.1 2.1 2 0 0 2 2 2 1 FlxA-like protein DUF812 PF05667.11 KFP22109.1 - 0.0058 15.6 5.7 0.0066 15.4 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) APG6_N PF17675.1 KFP22109.1 - 0.0086 16.6 7.1 0.0086 16.6 7.1 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFP22109.1 - 0.0099 16.1 8.6 0.0099 16.1 8.6 1.5 2 0 0 2 2 1 1 TATA element modulatory factor 1 TATA binding DUF1706 PF08020.11 KFP22109.1 - 0.049 13.5 0.9 0.049 13.5 0.9 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1706) Spc7 PF08317.11 KFP22109.1 - 0.12 11.3 9.2 0.19 10.5 9.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KFP22109.1 - 0.15 10.7 5.4 0.12 11.0 4.3 1.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Prominin PF05478.11 KFP22109.1 - 0.15 10.0 1.2 0.19 9.7 1.2 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 KFP22109.1 - 0.24 11.4 2.7 0.39 10.8 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 KFP22109.1 - 0.34 10.5 4.5 0.033 13.8 0.5 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4140 PF13600.6 KFP22109.1 - 0.36 11.3 15.0 0.68 10.4 1.2 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.13 KFP22109.1 - 0.36 11.3 8.6 0.37 11.3 2.6 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AAA_15 PF13175.6 KFP22109.1 - 0.39 10.4 8.1 0.53 9.9 8.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain TolA_bind_tri PF16331.5 KFP22109.1 - 0.46 10.6 12.5 2.4 8.3 12.5 2.0 1 1 0 1 1 1 0 TolA binding protein trimerisation TSC22 PF01166.18 KFP22109.1 - 1.3 9.3 17.4 0.13 12.6 4.1 2.6 2 1 1 3 3 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KFP22109.1 - 1.7 8.8 18.8 0.099 12.8 2.7 2.6 2 1 1 3 3 2 0 bZIP transcription factor DUF724 PF05266.14 KFP22109.1 - 1.9 8.3 9.7 0.057 13.2 3.7 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF724) Tubulin_3 PF14881.6 KFP22109.1 - 2.7 7.7 4.8 0.87 9.2 2.2 1.5 2 0 0 2 2 1 0 Tubulin domain HAP1_N PF04849.13 KFP22109.1 - 2.9 7.0 17.3 1.7 7.8 2.9 2.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region V_ATPase_I PF01496.19 KFP22109.1 - 3 5.6 7.7 1.1 7.0 4.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Nnf1 PF03980.14 KFP22109.1 - 3.4 8.1 14.7 1.2 9.6 1.4 2.7 2 1 1 3 3 3 0 Nnf1 Fmp27_WPPW PF10359.9 KFP22109.1 - 3.8 6.3 10.4 0.16 10.8 4.6 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain CENP-H PF05837.12 KFP22109.1 - 4.4 7.7 14.4 0.4 11.1 1.8 2.6 2 1 2 4 4 4 0 Centromere protein H (CENP-H) TMCO5 PF14992.6 KFP22109.1 - 4.5 6.8 14.1 1 8.9 10.7 1.7 2 0 0 2 2 2 0 TMCO5 family YabA PF06156.13 KFP22109.1 - 6.5 7.5 13.7 0.2 12.3 4.1 2.4 2 1 1 3 3 2 0 Initiation control protein YabA Med21 PF11221.8 KFP22109.1 - 9.9 6.4 19.5 4.6e+02 1.0 19.5 2.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex PRKG1_interact PF15898.5 KFP22110.1 - 2.4e-33 115.1 14.6 2.4e-33 115.1 14.6 6.3 6 2 1 7 7 7 1 cGMP-dependent protein kinase interacting domain Ank_4 PF13637.6 KFP22110.1 - 4.1e-29 100.6 0.4 5.6e-12 45.9 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP22110.1 - 2.4e-27 95.3 0.4 4.4e-13 49.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP22110.1 - 1.3e-23 82.8 3.2 3.4e-07 30.4 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFP22110.1 - 5.3e-20 70.9 0.3 0.0031 17.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFP22110.1 - 3.3e-16 57.7 1.7 0.017 15.6 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ribosomal_S9 PF00380.19 KFP22113.1 - 1.9e-32 112.3 0.1 2.2e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 VWD PF00094.25 KFP22114.1 - 1.4e-93 311.3 25.4 2.3e-27 96.2 0.6 4.7 5 0 0 5 5 5 4 von Willebrand factor type D domain C8 PF08742.11 KFP22114.1 - 1.4e-43 147.2 56.9 6.1e-16 58.6 3.5 9.9 10 1 0 10 10 10 4 C8 domain TIL PF01826.17 KFP22114.1 - 4.5e-12 46.0 75.8 1.3e-06 28.5 15.5 17.1 14 2 3 17 17 17 5 Trypsin Inhibitor like cysteine rich domain AbfB PF05270.13 KFP22114.1 - 1.8e-08 34.5 0.2 3.8e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain fn3 PF00041.21 KFP22115.1 - 0.023 15.0 0.4 0.6 10.5 0.4 2.0 1 1 0 1 1 1 0 Fibronectin type III domain DUF4680 PF15730.5 KFP22115.1 - 0.19 12.1 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) fn3 PF00041.21 KFP22116.1 - 5.3e-178 577.9 64.8 3.1e-13 49.9 0.2 20.3 19 2 1 20 20 20 19 Fibronectin type III domain Y_phosphatase PF00102.27 KFP22116.1 - 9.8e-75 251.1 0.0 2e-74 250.1 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 KFP22116.1 - 3.7e-19 69.1 57.5 0.0012 19.4 0.0 17.4 15 4 0 16 16 16 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP22116.1 - 8.2e-11 42.1 3.6 2.7 8.3 0.0 11.4 13 0 0 13 13 13 2 Interferon-alpha/beta receptor, fibronectin type III DUF4959 PF16323.5 KFP22116.1 - 1.3e-05 25.4 4.6 0.039 14.3 0.1 6.4 5 3 1 6 6 6 1 Domain of unknown function (DUF4959) Y_phosphatase3 PF13350.6 KFP22116.1 - 0.00024 21.2 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KFP22116.1 - 0.03 14.2 0.0 0.093 12.5 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP22116.1 - 0.083 13.0 0.1 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate FeoB_associated PF12669.7 KFP22116.1 - 0.22 11.9 0.1 0.47 10.9 0.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2369 PF10179.9 KFP22116.1 - 0.48 10.9 10.5 28 5.2 0.0 7.0 10 0 0 10 10 10 0 Uncharacterised conserved protein (DUF2369) Basic PF01586.16 KFP22117.1 - 3.8e-24 85.6 0.1 1.1e-23 84.2 0.0 1.8 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.26 KFP22117.1 - 2.8e-13 49.6 6.0 4.7e-13 48.9 6.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myf5 PF12232.8 KFP22117.1 - 0.0011 19.7 0.2 0.0011 19.7 0.2 1.9 2 0 0 2 2 2 1 Myogenic determination factor 5 PDZ PF00595.24 KFP22118.1 - 7.5e-21 74.3 0.4 1.2e-20 73.6 0.4 1.3 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KFP22118.1 - 1.1e-14 53.9 0.1 2.6e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 KFP22118.1 - 1.1e-13 50.7 0.3 3.4e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KFP22118.1 - 0.00068 19.9 0.1 0.0015 18.8 0.0 1.5 2 0 0 2 2 2 1 PDZ domain AMP-binding PF00501.28 KFP22119.1 - 1.4e-81 274.3 0.0 1.7e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFP22119.1 - 2.7e-20 73.1 2.6 3.4e-20 72.8 1.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFP22119.1 - 0.11 12.4 1.8 0.15 12.0 0.3 2.0 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus RVT_1 PF00078.27 KFP22125.1 - 0.0012 18.4 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rRNA_processing PF08524.11 KFP22126.1 - 1.4e-12 47.9 31.9 1.4e-12 47.9 31.9 2.1 1 1 1 2 2 2 1 rRNA processing DUF4554 PF15091.6 KFP22126.1 - 1 8.2 12.5 1.1 8.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) KGK PF08872.10 KFP22126.1 - 1.5 9.4 9.2 0.25 11.8 5.5 1.6 2 0 0 2 2 2 0 KGK domain Methyltransf_32 PF13679.6 KFP22127.1 - 3e-32 111.8 10.4 2.5e-30 105.5 10.4 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP22127.1 - 0.00016 22.3 0.0 0.00068 20.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP22127.1 - 0.0023 17.8 0.0 0.0069 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFP22127.1 - 0.0026 17.6 0.0 0.0096 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP22127.1 - 0.0027 18.3 0.0 0.022 15.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFP22127.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KFP22127.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KFP22127.1 - 0.045 13.3 0.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 KFP22127.1 - 0.046 14.5 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NapE PF06796.11 KFP22127.1 - 0.15 11.6 0.0 0.58 9.7 0.0 2.0 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE TPR_1 PF00515.28 KFP22129.1 - 1.2e-34 116.7 25.1 5.3e-05 22.9 0.2 9.7 8 1 2 10 10 10 8 Tetratricopeptide repeat DUF1736 PF08409.11 KFP22129.1 - 1.4e-30 105.0 1.4 3.3e-30 103.9 1.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 KFP22129.1 - 3e-30 101.9 20.4 0.00028 20.8 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22129.1 - 4.2e-28 95.2 21.5 0.0043 17.2 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22129.1 - 6.7e-23 80.8 18.9 7.6e-08 32.5 0.0 6.5 5 3 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22129.1 - 7.7e-19 67.1 9.6 0.00051 19.7 0.3 6.6 5 2 3 8 8 7 4 TPR repeat TPR_16 PF13432.6 KFP22129.1 - 1.3e-16 60.9 7.0 0.00011 22.8 0.0 6.6 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22129.1 - 6.2e-16 57.2 7.1 0.0052 16.7 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP22129.1 - 6.7e-12 44.9 29.5 0.1 12.5 0.0 9.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22129.1 - 1.3e-11 44.0 13.6 0.23 11.9 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22129.1 - 2.2e-11 43.5 7.7 3.7 8.6 0.0 8.9 6 3 3 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22129.1 - 1.1e-07 31.9 0.2 0.28 11.4 0.0 4.6 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22129.1 - 1.3e-07 32.0 11.0 0.011 16.2 0.0 5.3 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFP22129.1 - 1.3e-07 31.8 4.0 0.1 13.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP22129.1 - 2.2e-07 30.6 0.9 0.00026 20.5 0.0 3.6 2 1 2 4 4 4 2 MalT-like TPR region NARP1 PF12569.8 KFP22129.1 - 5.8e-07 28.8 2.3 0.052 12.5 0.4 3.1 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 KFP22129.1 - 8e-06 26.0 12.0 0.02 15.1 1.2 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KFP22129.1 - 4.7e-05 23.3 12.1 0.51 10.4 0.3 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat PMT_2 PF13231.6 KFP22129.1 - 0.00043 20.5 3.0 0.00043 20.5 3.0 2.6 3 0 0 3 3 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_21 PF09976.9 KFP22129.1 - 0.0005 19.8 0.0 5.4 6.7 0.0 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KFP22129.1 - 0.00095 19.6 0.0 22 6.0 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat FAT PF02259.23 KFP22129.1 - 0.0024 17.2 2.5 0.028 13.7 0.6 2.2 1 1 1 2 2 2 1 FAT domain PMT PF02366.18 KFP22129.1 - 0.0026 17.4 7.9 0.0026 17.4 7.9 1.8 2 0 0 2 2 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_15 PF13429.6 KFP22129.1 - 0.0055 16.0 6.6 0.048 12.9 0.3 3.8 3 1 2 5 5 5 1 Tetratricopeptide repeat Sel1 PF08238.12 KFP22129.1 - 0.014 16.1 6.7 1e+02 3.8 0.1 6.2 6 0 0 6 6 5 0 Sel1 repeat DUF389 PF04087.14 KFP22129.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF389) RPN7 PF10602.9 KFP22129.1 - 0.16 11.6 1.0 4.8 6.9 0.0 3.4 2 1 1 3 3 3 0 26S proteasome subunit RPN7 SNAP PF14938.6 KFP22129.1 - 1.4 8.2 7.4 26 4.1 0.0 3.2 1 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP PPR PF01535.20 KFP22129.1 - 3.5 8.1 9.1 11 6.6 0.4 5.4 6 0 0 6 6 4 0 PPR repeat DUF2225 PF09986.9 KFP22129.1 - 7.6 6.2 8.3 0.52 10.0 0.3 2.8 3 1 1 4 4 2 0 Uncharacterized protein conserved in bacteria (DUF2225) IQ PF00612.27 KFP22138.1 - 5.2e-06 25.8 0.0 1.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Homeodomain PF00046.29 KFP22139.1 - 7e-24 83.4 6.3 1.6e-23 82.3 6.3 1.6 1 0 0 1 1 1 1 Homeodomain OAR PF03826.17 KFP22139.1 - 3.9e-09 36.0 3.2 9.2e-09 34.9 3.2 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.11 KFP22139.1 - 0.0011 18.8 0.2 0.0035 17.2 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain RA PF00788.23 KFP22141.1 - 4.7e-07 30.4 0.5 1.1e-05 26.0 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ly49 PF08391.10 KFP22141.1 - 5.2 7.5 11.1 0.89 9.9 0.7 2.7 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Pro-NT_NN PF07421.11 KFP22142.1 - 1.2e-52 178.4 0.8 1.3e-52 178.3 0.8 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor DUF1729 PF08354.10 KFP22142.1 - 0.064 12.1 0.2 0.086 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) LisH_2 PF16045.5 KFP22145.1 - 4.5e-15 54.4 0.4 1.1e-14 53.1 0.4 1.7 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 KFP22145.1 - 0.002 18.3 0.4 0.85 9.9 0.0 4.1 3 0 0 3 3 3 1 FOP N terminal dimerisation domain LisH PF08513.11 KFP22145.1 - 0.0021 17.9 0.0 0.0058 16.6 0.0 1.8 1 0 0 1 1 1 1 LisH Sedlin_N PF04628.13 KFP22146.1 - 5.7e-45 152.6 0.6 2.9e-44 150.4 0.6 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KFP22146.1 - 5.9e-09 36.0 0.1 9.3e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family Ras PF00071.22 KFP22147.1 - 3.3e-57 192.6 0.0 3.8e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22147.1 - 4.1e-30 104.5 0.0 6.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22147.1 - 1.2e-11 44.4 0.0 1.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP22147.1 - 6.2e-06 26.3 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFP22147.1 - 6.5e-05 22.9 0.0 0.011 15.6 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KFP22147.1 - 0.00015 21.2 0.0 0.00018 20.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KFP22147.1 - 0.0036 17.1 0.3 0.019 14.8 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KFP22147.1 - 0.0079 15.8 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KFP22147.1 - 0.0085 15.8 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KFP22147.1 - 0.021 14.3 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KFP22147.1 - 0.022 15.2 0.0 0.036 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KFP22147.1 - 0.032 13.4 2.2 0.76 8.9 0.2 2.5 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 KFP22147.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 2 1 1 3 3 3 0 Ferrous iron transport protein B TFIIS_M PF07500.14 KFP22148.1 - 2e-28 99.1 3.2 2e-28 99.1 3.2 2.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KFP22148.1 - 5.6e-12 45.5 0.7 1.6e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_C PF01096.18 KFP22148.1 - 0.0088 15.9 0.2 0.0088 15.9 0.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) MutS_III PF05192.18 KFP22148.1 - 0.23 11.6 7.8 0.58 10.3 7.6 1.8 1 1 0 1 1 1 0 MutS domain III Ribosomal_L37e PF01907.19 KFP22148.1 - 0.4 10.9 4.2 2.5 8.3 0.4 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e EGF_CA PF07645.15 KFP22150.1 - 6.1e-23 80.8 39.5 2.6e-10 40.3 7.0 6.2 4 2 1 5 5 5 3 Calcium-binding EGF domain MAM PF00629.23 KFP22150.1 - 1.3e-20 73.9 0.0 3e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu cEGF PF12662.7 KFP22150.1 - 1.5e-16 60.0 37.6 2.4e-05 24.2 0.5 5.8 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 KFP22150.1 - 1.3e-11 44.5 21.7 1.1e-09 38.3 11.0 6.3 5 1 0 5 5 5 3 EGF domain FXa_inhibition PF14670.6 KFP22150.1 - 2.7e-10 40.3 75.1 7.8e-06 26.1 8.8 5.5 3 1 2 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP22150.1 - 1.5e-09 37.9 72.2 0.00012 22.3 5.6 6.4 6 0 0 6 6 6 4 EGF-like domain hEGF PF12661.7 KFP22150.1 - 0.0021 18.6 1.2 0.0021 18.6 1.2 7.8 7 1 0 7 7 7 3 Human growth factor-like EGF LRR_8 PF13855.6 KFP22152.1 - 1.1e-69 230.1 104.4 3.2e-10 39.6 5.2 14.5 8 4 9 17 17 17 17 Leucine rich repeat LRR_4 PF12799.7 KFP22152.1 - 4e-35 119.2 104.9 1.1e-05 25.7 2.7 15.0 6 5 11 19 19 19 16 Leucine Rich repeats (2 copies) TIR PF01582.20 KFP22152.1 - 3.3e-17 62.8 0.1 5.6e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.6 KFP22152.1 - 7.8e-14 51.7 28.1 3.1e-07 30.4 0.8 6.7 4 1 2 6 6 6 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KFP22152.1 - 1.1e-13 51.1 40.1 3.2e-05 23.5 4.2 7.5 3 2 2 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 KFP22152.1 - 4.5e-13 47.8 86.9 1.5 9.7 0.1 21.2 20 4 1 21 21 21 7 Leucine Rich Repeat LRR_12 PF18837.1 KFP22152.1 - 2.1e-09 36.9 0.9 2.1e-09 36.9 0.9 4.9 4 0 0 4 4 4 1 Leucine-rich repeat TIR_2 PF13676.6 KFP22152.1 - 3.7e-09 37.2 0.2 1.2e-08 35.6 0.1 1.8 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.6 KFP22152.1 - 0.0051 16.8 78.3 1.1 9.5 0.0 18.0 20 0 0 20 20 20 3 Leucine Rich repeat Cytokin_check_N PF10407.9 KFP22152.1 - 0.051 13.5 0.2 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Pribosyl_synth PF14572.6 KFP22153.1 - 9.3e-45 152.9 2.1 3.6e-37 128.2 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFP22153.1 - 2.1e-33 114.7 0.3 1.2e-32 112.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFP22153.1 - 1.7e-13 50.4 0.2 3.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFP22153.1 - 0.00036 20.1 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF3247 PF11607.8 KFP22153.1 - 0.16 12.3 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) FERM_M PF00373.18 KFP22154.1 - 3.2e-18 66.2 0.1 9.3e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.24 KFP22154.1 - 1.7e-10 41.1 0.0 3.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP22154.1 - 1.6e-07 31.1 0.1 3.7e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP22154.1 - 5.4e-05 23.4 0.0 0.00019 21.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain WW PF00397.26 KFP22154.1 - 0.0013 18.7 0.1 0.0031 17.6 0.1 1.7 1 0 0 1 1 1 1 WW domain FERM_f0 PF16511.5 KFP22154.1 - 0.0037 17.5 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Vfa1 PF08432.10 KFP22154.1 - 0.061 13.6 8.2 0.017 15.5 2.0 2.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Jak1_Phl PF17887.1 KFP22154.1 - 5.8 6.9 5.6 0.54 10.2 0.1 2.2 3 0 0 3 3 3 0 Jak1 pleckstrin homology-like domain MRG PF05712.13 KFP22156.1 - 4.5e-70 235.0 0.5 6.3e-70 234.5 0.5 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFP22156.1 - 3.8e-05 23.5 0.4 9.7e-05 22.2 0.4 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KFP22156.1 - 0.017 15.0 0.2 0.043 13.7 0.2 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF87 PF01935.17 KFP22156.1 - 0.44 10.6 2.3 0.74 9.9 2.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain RhoGAP PF00620.27 KFP22162.1 - 8.7e-48 162.0 0.0 1.8e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF1679 PF07914.11 KFP22162.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Yae1_N PF09811.9 KFP22163.1 - 4.7e-13 48.6 40.6 1.8e+04 -5.2 40.6 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal COS PF18568.1 KFP22165.1 - 2.5e-34 117.0 2.4 3.1e-34 116.7 0.8 2.1 3 0 0 3 3 3 1 TRIM C-terminal subgroup One Signature domain SPRY PF00622.28 KFP22165.1 - 5.7e-17 61.9 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.6 KFP22165.1 - 7.3e-13 47.9 0.0 2.8e-12 46.0 0.0 2.1 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.24 KFP22165.1 - 3.5e-09 36.7 0.8 3.5e-09 36.7 0.8 5.1 5 1 0 5 5 3 2 B-box zinc finger fn3 PF00041.21 KFP22165.1 - 3.2e-08 33.8 0.2 6.7e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 KFP22165.1 - 4.1e-07 29.9 9.6 4.1e-07 29.9 9.6 4.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP22165.1 - 1.2e-06 28.3 7.5 1.2e-06 28.3 7.5 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP22165.1 - 3.6e-06 26.7 11.6 3.6e-06 26.7 11.6 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP22165.1 - 9.4e-06 25.7 12.3 9.4e-06 25.7 12.3 5.4 5 1 1 6 6 6 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KFP22165.1 - 1.1e-05 25.2 7.1 1.1e-05 25.2 7.1 5.0 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP22165.1 - 7.7e-05 22.9 11.4 7.7e-05 22.9 11.4 3.8 4 0 0 4 4 3 2 Ring finger domain zf-RING_5 PF14634.6 KFP22165.1 - 0.0017 18.3 9.9 0.0017 18.3 9.9 4.5 4 1 0 4 4 3 1 zinc-RING finger domain Pur_ac_phosph_N PF16656.5 KFP22165.1 - 0.0076 16.8 0.2 0.019 15.6 0.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KFP22165.1 - 0.061 13.2 0.0 0.26 11.2 0.0 2.0 3 0 0 3 3 3 0 Fibronectin-III type domain Serine_rich PF08824.10 KFP22165.1 - 0.32 11.0 7.6 3.3 7.7 7.5 2.2 1 1 0 1 1 1 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.12 KFP22165.1 - 0.37 10.8 6.2 0.099 12.7 0.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Voltage_CLC PF00654.20 KFP22166.1 - 1.4e-99 333.7 16.4 1.4e-99 333.7 16.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFP22166.1 - 2.5e-13 50.2 0.7 6.4e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain C2 PF00168.30 KFP22167.1 - 0.00026 21.2 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF4055 PF13264.6 KFP22167.1 - 2.3 8.3 7.2 3 8.0 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) Claudin_2 PF13903.6 KFP22168.1 - 5.7e-14 52.3 7.8 7e-14 52.0 7.8 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP22168.1 - 3.8e-06 26.9 11.8 6.7e-06 26.1 11.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family ASD2 PF08687.11 KFP22169.1 - 4.4e-120 400.7 26.0 4.4e-120 400.7 26.0 3.7 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 ASD1 PF08688.10 KFP22169.1 - 5.5e-58 196.2 4.8 5.5e-58 196.2 4.8 5.4 4 1 1 5 5 5 1 Apx/Shroom domain ASD1 Ocular_alb PF02101.15 KFP22170.1 - 3.8e-204 678.1 7.0 4.6e-204 677.9 7.0 1.0 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.24 KFP22170.1 - 0.00083 18.7 10.7 0.0014 17.9 10.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KFP22170.1 - 1.5 8.1 13.1 2.6 7.3 13.1 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) WD40 PF00400.32 KFP22171.1 - 2.4e-53 176.9 27.3 1.7e-10 41.3 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP22171.1 - 2.6e-31 107.8 1.8 7.2e-09 35.8 0.0 6.3 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFP22171.1 - 2.6e-11 43.8 0.4 0.0018 18.2 0.1 3.6 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFP22171.1 - 1.4e-05 24.2 0.9 0.15 11.0 0.0 3.5 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFP22171.1 - 0.00021 20.8 0.0 1.2 8.4 0.0 3.2 4 1 0 4 4 4 2 WD40-like domain IKI3 PF04762.12 KFP22171.1 - 0.022 12.8 0.3 0.28 9.1 0.0 2.4 2 1 1 3 3 3 0 IKI3 family Glyco_hydro_11 PF00457.17 KFP22171.1 - 0.034 13.8 1.2 1.4 8.5 0.1 2.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 PD40 PF07676.12 KFP22171.1 - 0.034 14.1 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFP22171.1 - 0.038 12.6 4.7 0.27 9.8 0.0 3.4 2 2 3 5 5 5 0 Nucleoporin Nup120/160 PI-PLC-X PF00388.19 KFP22172.1 - 1.8e-58 196.3 0.2 7.4e-58 194.3 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.10 KFP22172.1 - 4.7e-47 160.2 46.6 4.7e-47 160.2 46.6 3.0 3 0 0 3 3 3 1 PLC-beta C terminal PI-PLC-Y PF00387.19 KFP22172.1 - 5.9e-40 136.2 1.5 5.9e-40 136.2 1.5 4.0 2 1 2 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KFP22172.1 - 7.7e-19 67.9 0.0 2.1e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 KFP22172.1 - 4.4e-11 43.1 0.0 4.4e-11 43.1 0.0 3.2 2 1 2 4 4 4 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP22172.1 - 2.2e-07 31.1 0.2 8.1e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain DUF1154 PF06631.11 KFP22172.1 - 1e-06 28.7 10.8 1e-06 28.7 10.8 3.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) DUF760 PF05542.11 KFP22172.1 - 0.057 13.8 0.4 15 6.0 0.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF760) DUF4510 PF14971.6 KFP22172.1 - 1.1 9.6 12.3 26 5.2 9.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4510) PI-PLC-X PF00388.19 KFP22173.1 - 5.3e-63 211.0 0.9 1.5e-62 209.5 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PH_14 PF17787.1 KFP22173.1 - 1.3e-42 144.8 0.0 1.3e-42 144.8 0.0 2.5 2 1 1 3 3 3 1 PH domain PI-PLC-Y PF00387.19 KFP22173.1 - 3.3e-42 143.5 0.4 3.3e-42 143.5 0.4 3.9 4 1 0 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF1154 PF06631.11 KFP22173.1 - 2.8e-17 62.4 13.1 2.8e-17 62.4 13.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 KFP22173.1 - 1.2e-13 51.4 1.0 5.7e-13 49.2 0.0 2.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KFP22173.1 - 1.7e-08 34.6 0.0 4.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KFP22173.1 - 0.098 13.1 0.6 0.41 11.1 0.6 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KFP22173.1 - 0.15 12.0 0.6 0.56 10.3 0.6 2.0 1 0 0 1 1 1 0 EF-hand domain Lamp PF01299.17 KFP22174.1 - 1.2e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KFP22174.1 - 7.8e-07 29.0 0.9 1.6e-06 28.0 0.9 1.6 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Chordopox_A13L PF05961.11 KFP22174.1 - 0.028 14.6 0.1 0.065 13.5 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Pkinase PF00069.25 KFP22175.1 - 1.4e-68 231.1 0.0 1.8e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22175.1 - 5e-45 153.8 0.0 7.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFP22175.1 - 1.5e-15 57.3 0.1 4.3e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KFP22175.1 - 4.4e-08 32.8 0.0 8.5e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFP22175.1 - 8.4e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP22175.1 - 0.1 12.5 0.2 3.4 7.5 0.0 2.9 1 1 2 3 3 3 0 Phosphotransferase enzyme family adh_short PF00106.25 KFP22176.1 - 7.5e-22 77.7 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP22176.1 - 2e-14 53.7 0.0 2.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFP22176.1 - 6.5e-06 25.7 0.0 7.3e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HMG_box PF00505.19 KFP22176.1 - 0.00069 20.0 0.7 0.0016 18.8 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box Ank_2 PF12796.7 KFP22178.1 - 2.5e-52 175.4 6.2 1.7e-10 41.4 0.1 5.7 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP22178.1 - 4.9e-44 148.1 11.0 1e-14 54.6 0.0 8.7 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KFP22178.1 - 5.4e-43 143.6 12.0 3.7e-07 30.3 0.0 9.3 8 1 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KFP22178.1 - 9.9e-43 139.2 9.3 9e-07 28.7 0.0 10.5 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KFP22178.1 - 1.4e-39 133.6 13.6 5.9e-08 32.8 0.0 8.7 4 3 6 10 10 10 8 Ankyrin repeats (many copies) SNAP-25 PF00835.19 KFP22179.1 - 2.8e-21 75.5 1.2 3.6e-21 75.2 0.2 1.7 2 0 0 2 2 1 1 SNAP-25 family DUF5089 PF17002.5 KFP22179.1 - 1.9e-06 27.9 0.9 2.7e-06 27.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) Use1 PF09753.9 KFP22179.1 - 0.039 13.7 0.5 0.039 13.7 0.5 1.8 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF4200 PF13863.6 KFP22179.1 - 0.044 14.2 4.6 1.7 9.1 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) SOAR PF16533.5 KFP22179.1 - 0.046 13.7 1.7 3.4 7.7 0.0 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region RmuC PF02646.16 KFP22179.1 - 0.064 12.4 0.6 1.7 7.7 0.3 2.0 2 0 0 2 2 2 0 RmuC family DivIC PF04977.15 KFP22179.1 - 0.076 12.8 1.9 3 7.7 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Snapin_Pallidin PF14712.6 KFP22179.1 - 0.086 13.3 1.1 12 6.4 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin V-SNARE_C PF12352.8 KFP22179.1 - 0.13 12.6 4.9 0.48 10.8 0.1 3.2 3 1 1 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus DUF349 PF03993.12 KFP22179.1 - 0.18 12.1 1.3 0.56 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Laminin_II PF06009.12 KFP22179.1 - 0.21 11.6 2.6 16 5.5 0.9 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 KFP22179.1 - 0.22 11.8 0.9 13 6.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 KFP22179.1 - 0.23 10.4 4.9 0.97 8.3 0.3 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Rx_N PF18052.1 KFP22179.1 - 0.34 11.2 3.8 0.24 11.7 0.2 2.0 2 0 0 2 2 2 0 Rx N-terminal domain XhlA PF10779.9 KFP22179.1 - 0.48 10.6 10.5 2.4 8.4 0.9 2.8 3 0 0 3 3 3 0 Haemolysin XhlA DUF4446 PF14584.6 KFP22179.1 - 0.57 10.2 2.7 23 4.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4665 PF15679.5 KFP22179.1 - 0.68 10.6 3.6 3.1 8.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) CCDC-167 PF15188.6 KFP22179.1 - 0.86 10.0 5.4 7.1 7.1 0.4 2.5 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 LTXXQ PF07813.12 KFP22179.1 - 1.8 9.4 6.0 11 6.8 0.6 2.5 2 1 0 2 2 2 0 LTXXQ motif family protein DUF16 PF01519.16 KFP22179.1 - 2.2 8.8 6.1 13 6.3 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 SNARE PF05739.19 KFP22179.1 - 2.5 8.2 8.4 1.2 9.2 0.5 2.6 3 0 0 3 3 3 0 SNARE domain SlyX PF04102.12 KFP22179.1 - 3.9 8.2 6.2 27 5.5 0.7 2.5 2 1 0 2 2 2 0 SlyX Cpn60_TCP1 PF00118.24 KFP22180.1 - 8.1e-98 328.2 0.0 9.2e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UPF0492 PF15744.5 KFP22181.1 - 4.3e-163 542.8 12.1 5e-163 542.6 12.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0492 EGF PF00008.27 KFP22182.1 - 8.7e-80 262.5 284.6 2e-09 37.6 7.7 19.3 19 2 1 20 20 18 14 EGF-like domain hEGF PF12661.7 KFP22182.1 - 1.6e-52 174.5 255.5 4.8e-07 30.2 7.3 20.8 22 0 0 22 22 20 14 Human growth factor-like EGF MNNL PF07657.13 KFP22182.1 - 5.1e-28 96.9 3.4 5.1e-28 96.9 3.4 6.7 7 1 0 7 7 1 1 N terminus of Notch ligand EGF_2 PF07974.13 KFP22182.1 - 4.3e-25 87.8 329.6 0.00022 21.5 6.7 19.7 20 0 0 20 20 17 13 EGF-like domain DSL PF01414.19 KFP22182.1 - 4.4e-24 84.5 7.7 4.4e-24 84.5 7.7 15.8 12 2 4 16 16 14 2 Delta serrate ligand EGF_CA PF07645.15 KFP22182.1 - 2.4e-07 30.8 284.3 5.8e-05 23.2 8.8 19.4 10 4 11 21 21 17 11 Calcium-binding EGF domain DUF2920 PF11144.8 KFP22182.1 - 0.0042 16.3 0.6 0.0068 15.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) IN_DBD_C PF00552.21 KFP22182.1 - 0.0073 15.6 0.2 0.049 12.9 0.2 2.4 1 1 0 1 1 1 1 Integrase DNA binding domain cEGF PF12662.7 KFP22182.1 - 0.011 15.7 3.3 0.011 15.7 3.3 17.3 16 3 0 16 16 16 0 Complement Clr-like EGF-like MAP17 PF15807.5 KFP22182.1 - 0.14 12.4 0.8 0.27 11.5 0.8 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CLN3 PF02487.17 KFP22182.1 - 0.33 9.9 0.2 0.48 9.4 0.2 1.1 1 0 0 1 1 1 0 CLN3 protein Pkinase_Tyr PF07714.17 KFP22184.1 - 5.2e-76 255.3 0.0 7.3e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KFP22184.1 - 2.2e-54 182.4 0.1 1.9e-29 102.1 0.1 2.7 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KFP22184.1 - 1.8e-34 119.3 0.0 2.7e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.20 KFP22184.1 - 5e-16 58.9 27.2 6.6e-16 58.5 22.1 2.6 2 1 0 2 2 2 1 Furin-like cysteine rich region fn3 PF00041.21 KFP22184.1 - 8.4e-16 58.1 4.3 1.7e-05 25.1 0.1 3.5 3 0 0 3 3 3 3 Fibronectin type III domain Insulin_TMD PF17870.1 KFP22184.1 - 0.037 14.1 0.1 0.077 13.1 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment B2 PF11473.8 KFP22184.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding protein B2 Kinase-like PF14531.6 KFP22184.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Furin-like_2 PF15913.5 KFP22184.1 - 8.9 6.5 15.1 0.48 10.6 5.4 3.1 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich PRCC PF10253.9 KFP22185.1 - 1.5e-54 186.1 8.0 1.5e-54 186.1 8.0 2.6 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting TEBP_beta PF07404.11 KFP22185.1 - 0.04 13.3 3.9 0.068 12.5 3.9 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) TSC22 PF01166.18 KFP22186.1 - 2.5e-27 94.9 5.8 2.8e-27 94.8 5.8 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 KFP22186.1 - 0.00012 22.6 2.5 0.00012 22.6 2.5 1.1 1 0 0 1 1 1 1 Initiation control protein YabA DivIC PF04977.15 KFP22186.1 - 0.0008 19.1 3.0 0.00089 19.0 3.0 1.1 1 0 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFP22186.1 - 0.0018 18.7 4.0 0.0025 18.2 4.0 1.3 1 0 0 1 1 1 1 Cell division protein ZapB TBK1_CCD1 PF18394.1 KFP22186.1 - 0.008 15.8 0.5 0.0083 15.7 0.5 1.1 1 0 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 bZIP_2 PF07716.15 KFP22186.1 - 0.025 14.7 5.6 0.045 13.8 5.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Tfb5 PF06331.12 KFP22186.1 - 0.066 13.2 1.0 0.091 12.8 1.0 1.2 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Amidase PF01425.21 KFP22187.1 - 2.7e-86 290.3 0.0 6e-86 289.2 0.0 1.6 1 1 0 1 1 1 1 Amidase GST_C_2 PF13410.6 KFP22189.1 - 7.2e-06 25.9 0.0 1.4e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFP22189.1 - 0.052 13.8 0.1 0.15 12.4 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFP22189.1 - 0.057 13.6 0.0 0.23 11.7 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1533 PF07550.11 KFP22189.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Gal_Lectin PF02140.18 KFP22190.1 - 1.7e-37 127.7 4.7 3.9e-19 68.9 0.7 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.6 KFP22190.1 - 8.2e-13 48.2 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 FAM176 family DUF3395 PF11875.8 KFP22190.1 - 0.02 14.8 0.0 2.5 8.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3395) Cys_Knot_tox PF17486.2 KFP22190.1 - 4.3 7.6 7.0 9.1 6.6 1.0 2.5 2 0 0 2 2 2 0 Cystine knot toxins Cyclin_N PF00134.23 KFP22191.1 - 7.1e-07 29.0 0.1 1.1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TGF_beta PF00019.20 KFP22192.1 - 2.6e-28 99.0 0.1 3.8e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain Glyco_hydro_15 PF00723.21 KFP22193.1 - 1.7e-167 557.8 0.0 2.2e-167 557.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Lipase_C PF18067.1 KFP22193.1 - 0.045 14.3 0.0 4 8.1 0.0 2.5 2 0 0 2 2 2 0 Lipase C-terminal domain Ribosomal_S4e PF00900.20 KFP22194.1 - 7.3e-40 134.7 0.5 1.2e-39 134.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFP22194.1 - 2.8e-08 33.3 0.5 5.3e-08 32.4 0.5 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 KFP22194.1 - 2.6e-06 27.0 0.0 5.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFP22194.1 - 5.5e-06 26.2 1.2 1.5e-05 24.8 0.2 2.4 2 0 0 2 2 2 1 KOW motif RS4NT PF08071.12 KFP22194.1 - 0.009 16.1 0.8 0.021 14.9 0.8 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain Sipho_tail PF05709.11 KFP22194.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Phage tail protein TMEM214 PF10151.9 KFP22195.1 - 2e-48 165.4 0.0 2.2e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator Peptidase_M14 PF00246.24 KFP22196.1 - 6.2e-10 39.3 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase ISPD_C PF18706.1 KFP22197.1 - 9e-52 175.1 6.4 1.3e-51 174.6 6.4 1.3 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain IspD PF01128.19 KFP22197.1 - 2.8e-29 102.5 0.1 1.2e-28 100.4 0.0 1.8 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TPALS PF18178.1 KFP22197.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family MIP-T3 PF10243.9 KFP22197.1 - 0.095 12.7 0.1 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 CH-like domain Thioredoxin_8 PF13905.6 KFP22197.1 - 0.22 11.9 1.2 0.54 10.6 0.3 2.2 2 1 0 2 2 2 0 Thioredoxin-like RVT_1 PF00078.27 KFP22198.1 - 0.0021 17.6 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sclerostin PF05463.11 KFP22199.1 - 1.1e-100 335.4 5.8 1.2e-100 335.2 5.8 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.15 KFP22199.1 - 1.6e-14 53.9 1.8 2.3e-14 53.4 1.8 1.3 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP22199.1 - 4.2e-05 23.8 7.6 0.00022 21.5 7.6 1.9 1 1 0 1 1 1 1 Cystine-knot domain LRR_9 PF14580.6 KFP22200.1 - 2.3e-18 66.3 3.2 5.1e-17 61.9 3.6 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KFP22200.1 - 4.2e-15 55.6 13.1 3.8e-06 27.2 0.2 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP22200.1 - 2.6e-09 36.7 26.5 8.4e-06 25.5 8.8 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 KFP22200.1 - 0.0069 16.8 10.1 10 7.1 0.0 4.8 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KFP22200.1 - 0.0092 16.0 4.3 2.7 8.3 0.2 3.8 3 0 0 3 3 3 2 Leucine Rich repeat Ank_2 PF12796.7 KFP22201.1 - 2.1e-12 47.5 0.2 3.3e-10 40.4 0.4 2.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFP22201.1 - 5.4e-11 42.4 0.2 6e-07 29.6 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFP22201.1 - 4.8e-10 38.8 0.2 2.3e-07 30.6 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KFP22201.1 - 1.1e-09 38.3 0.6 3.7e-06 27.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 KFP22201.1 - 1.7e-09 37.6 12.7 1.7e-09 37.6 12.7 2.4 2 0 0 2 2 2 1 MYND finger Ank_4 PF13637.6 KFP22201.1 - 2.5e-09 37.5 0.2 1.6e-07 31.7 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PolC_DP2 PF03833.13 KFP22201.1 - 0.067 11.1 5.3 0.094 10.6 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2151 PF10221.9 KFP22201.1 - 0.11 11.0 8.2 0.17 10.4 8.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator zf-Mss51 PF13824.6 KFP22201.1 - 0.18 11.9 5.6 0.64 10.2 5.6 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TraV PF09676.10 KFP22201.1 - 0.38 11.7 6.1 0.67 10.9 6.1 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Spore_coat_CotO PF14153.6 KFP22201.1 - 0.69 9.8 11.6 1.1 9.2 11.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO ATP-synt_E PF05680.12 KFP22201.1 - 1.6 9.1 7.2 2.9 8.3 7.2 1.4 1 0 0 1 1 1 0 ATP synthase E chain zf-C6H2 PF15801.5 KFP22201.1 - 7.7 6.9 18.9 1.4 9.3 12.1 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Trypan_PARP PF05887.11 KFP22201.1 - 8.8 6.3 14.3 2.7 8.0 11.6 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) W2 PF02020.18 KFP22202.1 - 4.1e-21 74.9 8.7 7.7e-21 74.0 4.4 2.9 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Tetraspanin PF00335.20 KFP22203.1 - 8.5e-16 58.4 9.8 1.1e-15 58.0 9.8 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF5373 PF17343.2 KFP22203.1 - 0.0079 16.1 0.4 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5373) DUF2981 PF11200.8 KFP22203.1 - 0.032 14.0 1.3 0.037 13.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4956 PF16316.5 KFP22203.1 - 0.16 11.6 4.3 0.27 10.9 4.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4956) DUF2207 PF09972.9 KFP22203.1 - 2.2 6.9 5.9 3.3 6.4 5.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GAPT PF11770.8 KFP22203.1 - 2.4 8.0 6.2 0.63 9.9 1.6 2.2 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) Ac76 PF05814.11 KFP22203.1 - 2.9 8.0 8.5 8 6.5 8.5 1.8 1 1 0 1 1 1 0 Orf76 (Ac76) Thioredoxin_7 PF13899.6 KFP22204.1 - 2.8e-23 81.9 0.0 6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFP22204.1 - 0.0044 17.5 0.1 0.028 14.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KFP22205.1 - 2.4e-25 88.5 0.3 5.6e-25 87.3 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredox_DsbH PF03190.15 KFP22205.1 - 3.2e-06 27.2 0.1 4.4e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KFP22205.1 - 5.4e-06 26.8 0.3 1.9e-05 25.0 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Pkinase PF00069.25 KFP22206.1 - 1.7e-58 198.0 0.0 2.4e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22206.1 - 8.3e-23 81.0 0.0 1.7e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFP22206.1 - 1.7e-06 28.2 0.0 0.0002 21.3 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFP22206.1 - 0.0021 17.5 0.7 0.0042 16.5 0.7 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP22206.1 - 0.0025 17.4 2.9 0.0041 16.7 2.9 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFP22206.1 - 0.018 14.6 1.7 0.096 12.3 1.7 2.0 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KFP22206.1 - 0.032 13.6 0.1 0.2 10.9 0.0 1.9 1 1 1 2 2 2 0 Kinase-like WaaY PF06176.11 KFP22206.1 - 0.037 13.6 2.4 0.059 13.0 2.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 KFP22206.1 - 0.092 12.3 1.4 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL TIP120 PF08623.10 KFP22207.1 - 3.2e-67 225.5 8.8 7.1e-65 217.9 0.8 5.6 4 1 2 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KFP22207.1 - 5.1e-22 78.1 1.0 0.011 16.1 0.0 9.5 7 2 2 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KFP22207.1 - 4.6e-21 74.9 7.1 0.00039 20.8 0.1 11.9 10 2 3 13 13 12 3 HEAT-like repeat HEAT PF02985.22 KFP22207.1 - 2.2e-18 64.7 19.5 0.079 13.3 0.0 13.1 16 0 0 16 16 11 5 HEAT repeat UME PF08064.13 KFP22207.1 - 1.9e-13 50.2 6.7 0.0083 16.0 0.1 8.1 6 2 1 8 8 8 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KFP22207.1 - 2.7e-09 37.5 5.7 0.0086 16.7 0.1 7.4 7 2 2 9 9 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFP22207.1 - 5.7e-09 35.9 2.9 0.095 12.3 0.0 6.2 6 1 1 7 7 7 2 CLASP N terminal Adaptin_N PF01602.20 KFP22207.1 - 7.2e-09 34.7 14.0 0.00023 19.9 0.1 6.0 2 2 1 4 4 4 4 Adaptin N terminal region Telomere_reg-2 PF10193.9 KFP22207.1 - 4.1e-08 33.6 6.1 0.49 10.8 0.0 6.8 7 0 0 7 7 5 1 Telomere length regulation protein Cnd1 PF12717.7 KFP22207.1 - 7.1e-08 32.6 17.1 0.055 13.5 0.4 7.8 7 1 0 9 9 8 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KFP22207.1 - 4e-07 29.5 20.5 0.00021 20.6 0.6 7.3 6 2 2 8 8 8 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KFP22207.1 - 3.9e-06 27.0 10.2 1.1 9.4 0.1 7.8 8 1 1 9 9 8 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 KFP22207.1 - 0.00023 21.1 9.5 0.00076 19.4 0.1 5.7 7 2 0 7 7 6 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KFP22207.1 - 0.00033 19.1 9.0 0.17 10.1 0.2 5.1 3 1 3 6 6 6 2 Down-regulated in metastasis RIX1 PF08167.12 KFP22207.1 - 0.00072 19.3 8.2 6.5 6.4 0.2 6.3 4 1 1 6 6 6 1 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 KFP22207.1 - 0.0053 17.0 0.1 3.6 8.0 0.0 4.6 3 2 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain V-ATPase_H_N PF03224.14 KFP22207.1 - 0.0065 15.8 5.8 1.6 8.0 0.3 4.7 3 1 2 5 5 5 1 V-ATPase subunit H VHS PF00790.19 KFP22207.1 - 0.0065 16.3 0.5 1.8 8.4 0.1 4.1 3 0 0 3 3 3 1 VHS domain API5 PF05918.11 KFP22207.1 - 0.0066 15.3 5.5 5 5.8 0.4 4.9 6 1 0 7 7 7 2 Apoptosis inhibitory protein 5 (API5) NUC173 PF08161.12 KFP22207.1 - 0.008 15.9 1.9 14 5.2 0.0 5.3 5 2 1 6 6 6 0 NUC173 domain RRN3 PF05327.11 KFP22207.1 - 0.023 13.2 0.5 0.075 11.6 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Uso1_p115_head PF04869.14 KFP22207.1 - 0.036 13.2 0.1 0.27 10.3 0.1 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Dopey_N PF04118.14 KFP22207.1 - 0.05 12.7 2.0 5.6 6.0 0.1 3.6 2 1 1 3 3 3 0 Dopey, N-terminal GhoS PF11080.8 KFP22207.1 - 0.16 11.9 0.0 0.66 10.0 0.0 2.0 1 0 0 1 1 1 0 Endoribonuclease GhoS V-ATPase_H_C PF11698.8 KFP22207.1 - 0.2 11.8 9.0 26 5.0 0.1 6.2 7 1 0 8 8 7 0 V-ATPase subunit H RasGEF_N_2 PF14663.6 KFP22207.1 - 0.5 10.8 2.8 40 4.7 0.1 4.5 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF4042 PF13251.6 KFP22207.1 - 2 8.1 5.7 46 3.6 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) 7tm_4 PF13853.6 KFP22208.1 - 1.4e-42 146.4 12.9 1.6e-42 146.1 12.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22208.1 - 1.6e-27 96.5 15.1 3.2e-27 95.5 15.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22209.1 - 6.9e-44 150.6 12.0 8.3e-44 150.4 12.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22209.1 - 6.9e-31 107.5 8.8 1e-30 107.0 8.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22209.1 - 8.5e-05 22.1 9.8 0.00012 21.6 9.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22209.1 - 0.0049 16.5 4.0 0.0049 16.5 4.0 1.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP22210.1 - 2.5e-31 109.4 8.8 3e-31 109.2 8.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22210.1 - 7.9e-30 104.1 8.9 1.3e-29 103.4 8.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP22210.1 - 0.0051 16.5 8.5 0.0089 15.7 8.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP22211.1 - 8.7e-47 160.2 12.7 1e-46 159.9 12.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22211.1 - 4.6e-31 108.1 15.2 8.6e-31 107.2 15.2 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22212.1 - 1.5e-41 143.0 13.3 1.7e-41 142.8 13.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22212.1 - 2.2e-24 86.2 16.3 3e-24 85.8 16.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEMspv1-c74-12 PF11044.8 KFP22212.1 - 4.5 7.3 4.7 12 6.0 4.7 1.7 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein 7tm_4 PF13853.6 KFP22213.1 - 4.2e-22 79.2 1.6 4.8e-22 79.0 1.6 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22213.1 - 1.4e-05 24.5 6.2 2.1e-05 24.0 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 KFP22214.1 - 3.3e-38 131.5 38.3 1.9e-34 119.2 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFP22214.1 - 0.0021 17.0 8.9 0.0021 17.0 8.9 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.9 KFP22214.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF202 PF02656.15 KFP22214.1 - 0.26 11.8 2.0 1.1 9.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Pardaxin PF07425.11 KFP22214.1 - 1.5 8.5 4.9 0.27 10.9 0.6 2.1 2 0 0 2 2 2 0 Pardaxin Peptidase_M76 PF09768.9 KFP22220.1 - 1.5e-55 187.6 6.6 1.7e-55 187.4 6.6 1.0 1 0 0 1 1 1 1 Peptidase M76 family HypD PF01924.16 KFP22220.1 - 0.0073 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase formation hypA family SprT-like PF10263.9 KFP22220.1 - 0.024 14.5 0.9 0.039 13.8 0.9 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M90 PF06167.12 KFP22220.1 - 0.044 13.4 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 TPR_1 PF00515.28 KFP22221.1 - 9.3e-36 120.2 24.8 2e-06 27.4 1.0 7.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22221.1 - 4.2e-28 95.2 23.9 9.9e-05 22.2 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.6 KFP22221.1 - 6.8e-26 90.7 2.1 1.1e-25 89.9 0.5 2.3 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 KFP22221.1 - 1.2e-19 68.8 18.0 0.0033 17.5 0.3 7.4 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22221.1 - 1e-16 60.3 16.6 8.1e-05 22.2 1.0 6.2 3 2 3 6 6 6 4 TPR repeat TPR_7 PF13176.6 KFP22221.1 - 4.6e-15 54.5 6.4 0.00011 22.0 0.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22221.1 - 4e-13 49.8 4.9 0.012 16.2 2.1 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22221.1 - 2.1e-11 43.6 1.8 0.037 14.8 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22221.1 - 7.4e-11 42.2 14.6 0.12 12.7 2.3 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22221.1 - 2.4e-10 40.4 0.3 0.0033 17.6 0.3 4.4 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22221.1 - 1.3e-08 35.2 9.7 0.018 15.6 1.7 4.7 2 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP22221.1 - 2.5e-05 24.6 9.7 2.3 9.0 0.3 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFP22221.1 - 0.00011 21.9 8.6 5.5 7.0 0.5 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22221.1 - 0.015 15.6 18.8 1 9.9 0.4 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KFP22221.1 - 0.026 14.6 11.5 2 8.5 0.2 4.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 KFP22221.1 - 0.037 14.1 20.2 0.046 13.8 0.1 5.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 KFP22221.1 - 0.13 12.5 5.2 11 6.6 0.1 4.4 5 0 0 5 5 4 0 PPR repeat ANAPC3 PF12895.7 KFP22221.1 - 0.15 12.3 7.7 0.33 11.2 0.8 3.3 3 1 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KFP22221.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.6 3 1 2 5 5 5 0 26S proteasome subunit RPN7 PPR_2 PF13041.6 KFP22221.1 - 3.8 7.8 4.5 32 4.8 0.1 3.3 4 0 0 4 4 3 0 PPR repeat family LRR_8 PF13855.6 KFP22224.1 - 3.2e-25 87.7 13.0 1.7e-13 50.1 5.6 4.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KFP22224.1 - 1.1e-12 47.9 18.6 6.3e-07 29.6 2.1 4.5 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP22224.1 - 4.9e-07 29.7 0.5 1.1e-06 28.7 0.5 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP22224.1 - 5.4e-07 29.3 18.5 0.078 13.6 0.3 7.5 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 KFP22224.1 - 1.8e-06 27.6 2.2 1.6e-05 24.5 0.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeat ig PF00047.25 KFP22224.1 - 9.2e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP22224.1 - 1.8e-05 25.2 0.0 4.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP22224.1 - 0.00028 20.9 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KFP22224.1 - 0.00032 20.8 0.0 0.00079 19.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 KFP22224.1 - 0.00055 19.8 15.2 0.26 11.4 0.3 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRRNT PF01462.18 KFP22224.1 - 0.0022 17.6 2.3 0.0022 17.6 2.3 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Herpes_gE PF02480.16 KFP22224.1 - 0.047 12.4 0.0 4.1 6.0 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Aa_trans PF01490.18 KFP22225.1 - 8e-81 271.8 34.0 3.8e-45 154.3 14.5 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFP22228.1 - 5.4e-79 265.8 40.5 6.2e-79 265.6 40.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KFP22229.1 - 5.8e-77 259.1 37.7 7.3e-77 258.8 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.21 KFP22229.1 - 0.00021 21.0 9.7 0.00021 21.0 9.7 3.1 2 2 1 3 3 3 1 Cation transporting ATPase, C-terminus ARID PF01388.21 KFP22231.1 - 7.6e-25 87.4 0.3 2.8e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 KFP22231.1 - 1.9e-23 82.9 0.1 3.8e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain BAF250_C PF12031.8 KFP22231.1 - 0.54 9.5 6.6 1 8.6 0.6 3.0 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa DnaJ_C PF01556.18 KFP22232.1 - 9.1e-31 106.9 0.0 1.2e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP22232.1 - 1.9e-11 43.9 0.1 3.7e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_6 PF12697.7 KFP22233.1 - 3.5e-29 103.0 0.0 9.8e-29 101.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP22233.1 - 1.2e-13 51.3 0.0 3.7e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP22233.1 - 4.7e-10 39.1 0.0 8.4e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFP22233.1 - 8.6e-05 22.8 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KFP22233.1 - 0.003 17.3 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KFP22233.1 - 0.005 16.7 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFP22233.1 - 0.0064 16.3 0.7 3.9 7.2 0.1 2.4 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KFP22233.1 - 0.021 14.5 0.1 0.071 12.7 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KFP22233.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) P4Ha_N PF08336.11 KFP22234.1 - 9.8e-22 77.4 0.0 1.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KFP22234.1 - 2.1e-11 44.6 0.0 5.1e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KFP22234.1 - 0.0031 17.5 0.3 2.6 8.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat SPO22 PF08631.10 KFP22234.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KFP22234.1 - 0.14 12.5 0.1 0.53 10.6 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat SPC25 PF06703.11 KFP22235.1 - 3.4e-45 153.7 0.3 4e-45 153.5 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) LRR_4 PF12799.7 KFP22236.1 - 2e-16 59.8 11.9 0.00023 21.5 0.3 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP22236.1 - 2e-09 37.0 17.3 0.0002 21.0 2.8 4.6 2 2 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KFP22236.1 - 1.2e-07 31.2 7.7 1 9.6 0.2 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KFP22236.1 - 6.6e-05 22.5 0.2 0.12 11.9 0.1 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KFP22236.1 - 0.051 14.1 12.5 58 4.8 0.2 6.8 6 1 0 6 6 6 0 Leucine Rich Repeat DUF4096 PF13340.6 KFP22236.1 - 0.086 13.1 0.1 0.73 10.1 0.0 2.5 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) Carb_anhydrase PF00194.21 KFP22238.1 - 2.8e-87 292.5 0.1 3.7e-87 292.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pentaxin PF00354.17 KFP22238.1 - 1.3e-38 132.6 0.1 2.1e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 KFP22238.1 - 1e-10 41.9 1.1 2.3e-10 40.8 1.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sugar_tr PF00083.24 KFP22239.1 - 1.1e-131 439.8 23.9 1.3e-131 439.6 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFP22239.1 - 2.7e-19 69.3 30.2 8.5e-18 64.4 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPRY PF00622.28 KFP22241.1 - 2.6e-19 69.5 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.16 KFP22241.1 - 4.1e-11 43.0 2.9 7.4e-11 42.2 2.9 1.4 1 0 0 1 1 1 1 SOCS box Mito_carr PF00153.27 KFP22242.1 - 6.4e-61 202.3 1.6 3.4e-20 71.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2448 PF10476.9 KFP22243.1 - 1.2e-94 316.0 1.1 1.8e-94 315.4 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) Ima1_N PF09779.9 KFP22243.1 - 2.6e-33 115.7 13.7 6.8e-33 114.4 13.7 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain zf-RRPl_C4 PF17026.5 KFP22243.1 - 0.65 10.1 14.4 0.15 12.2 10.5 2.0 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type PI3Ka PF00613.20 KFP22245.1 - 2e-55 187.1 4.2 3.6e-55 186.2 4.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP22245.1 - 7e-54 183.3 0.2 3.2e-52 177.8 0.2 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.16 KFP22245.1 - 2e-31 107.5 0.0 6.6e-31 105.9 0.0 2.0 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 KFP22245.1 - 1.2e-24 86.5 0.3 4.8e-24 84.6 0.1 2.2 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KFP22245.1 - 3.4e-23 82.1 0.0 7.9e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Cadherin PF00028.17 KFP22246.1 - 4e-15 56.0 0.0 3.8e-07 30.5 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.6 KFP22246.1 - 3.1e-05 24.2 0.0 6.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CDC45 PF02724.14 KFP22246.1 - 9.5e-05 20.9 2.6 0.00013 20.5 2.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Laminin_G_2 PF02210.24 KFP22246.1 - 0.0014 19.2 0.2 0.011 16.4 0.0 2.6 3 0 0 3 3 2 1 Laminin G domain V_ATPase_I PF01496.19 KFP22246.1 - 0.024 12.6 1.6 0.037 12.0 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 KFP22246.1 - 0.072 12.8 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Connexin SID-1_RNA_chan PF13965.6 KFP22246.1 - 0.096 11.1 0.5 0.15 10.5 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 KFP22246.1 - 0.14 11.4 2.6 0.23 10.7 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cadherin_C_2 PF16492.5 KFP22246.1 - 0.15 12.9 0.0 0.73 10.6 0.0 2.2 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 KFP22246.1 - 0.15 13.0 0.1 0.52 11.2 0.1 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RasGAP PF00616.19 KFP22246.1 - 1.5 8.5 3.7 2.8 7.6 3.7 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase TRAP_alpha PF03896.16 KFP22246.1 - 2.2 7.4 6.9 5.1 6.2 6.9 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ICAT PF06384.11 KFP22248.1 - 1.2e-19 70.3 0.0 1.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF3140 PF11338.8 KFP22248.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) ICAT PF06384.11 KFP22249.1 - 1e-32 112.2 0.1 1e-32 112.2 0.1 2.3 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 KFP22249.1 - 0.00036 20.2 1.1 0.00052 19.7 1.1 1.2 1 0 0 1 1 1 1 CAMP factor (Cfa) GvpG PF05120.12 KFP22249.1 - 0.0008 19.4 11.1 0.0026 17.7 0.3 2.4 2 0 0 2 2 2 1 Gas vesicle protein G Serine_rich PF08824.10 KFP22249.1 - 0.004 17.1 1.7 0.0062 16.6 1.7 1.3 1 0 0 1 1 1 1 Serine rich protein interaction domain Importin_rep_6 PF18829.1 KFP22249.1 - 0.049 13.8 0.6 0.087 13.0 0.6 1.4 1 0 0 1 1 1 0 Importin repeat 6 DUF3313 PF11769.8 KFP22249.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DMAP_binding PF06464.11 KFP22249.1 - 0.054 14.3 0.4 0.054 14.3 0.4 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain FlxA PF14282.6 KFP22249.1 - 0.066 13.2 11.1 0.13 12.3 8.9 2.2 1 1 1 2 2 2 0 FlxA-like protein Spc7 PF08317.11 KFP22249.1 - 0.066 12.1 8.6 0.083 11.8 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CK2S PF15011.6 KFP22249.1 - 0.069 13.0 9.0 0.62 9.9 0.1 2.9 1 1 2 3 3 3 0 Casein Kinase 2 substrate TetR_C_7 PF14246.6 KFP22249.1 - 0.09 12.8 0.5 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Laminin_II PF06009.12 KFP22249.1 - 0.24 11.4 5.4 2.1 8.4 0.8 2.6 1 1 1 2 2 2 0 Laminin Domain II WXG100 PF06013.12 KFP22249.1 - 0.24 11.6 2.9 0.5 10.6 0.9 2.5 2 2 0 2 2 2 0 Proteins of 100 residues with WXG Cauli_AT PF03233.13 KFP22249.1 - 0.36 10.7 3.1 0.71 9.8 3.1 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF4254 PF14063.6 KFP22249.1 - 0.42 10.4 5.9 0.47 10.2 1.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4254) DUF2408 PF10303.9 KFP22249.1 - 0.7 10.5 7.3 1.4 9.5 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Allexi_40kDa PF05549.11 KFP22249.1 - 0.8 9.2 3.4 1 8.8 3.0 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 KFP22249.1 - 1.3 9.5 5.4 1.4 9.4 3.4 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Baculo_p24 PF05073.12 KFP22249.1 - 1.5 8.5 4.5 14 5.5 2.6 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein XhlA PF10779.9 KFP22249.1 - 3.5 7.9 7.3 22 5.3 7.3 2.2 1 1 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 KFP22249.1 - 5.1 7.2 7.8 7.9 6.5 5.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 KFP22249.1 - 9.1 4.8 7.9 12 4.3 7.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A CTP_transf_like PF01467.26 KFP22250.1 - 1.3e-33 116.2 0.1 4.4e-33 114.5 0.1 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like ChapFlgA PF13144.6 KFP22250.1 - 0.076 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Lipocalin PF00061.23 KFP22251.1 - 3.5e-13 50.0 0.5 3.8e-13 49.9 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Glyco_hydro_43 PF04616.14 KFP22251.1 - 0.063 12.6 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Ufd2P_core PF10408.9 KFP22252.1 - 6.8e-202 672.4 14.7 8.8e-202 672.1 14.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFP22252.1 - 3.8e-26 91.1 1.1 9.1e-26 89.8 0.4 2.1 2 0 0 2 2 2 1 U-box domain Kinesin PF00225.23 KFP22253.1 - 1.1e-116 389.4 0.7 1.8e-116 388.7 0.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KFP22253.1 - 9e-87 289.9 0.4 9e-87 289.9 0.4 2.7 4 0 0 4 4 4 1 Kinesin-associated DUF3694 PF12473.8 KFP22253.1 - 4.7e-39 134.5 0.0 1.4e-38 133.0 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KFP22253.1 - 2.3e-25 89.2 0.1 6.9e-24 84.5 0.1 2.8 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 KFP22253.1 - 4.2e-13 49.7 0.1 2.4e-11 44.1 0.0 3.9 4 0 0 4 4 4 1 PH domain FHA PF00498.26 KFP22253.1 - 6.1e-08 32.9 0.3 2.6e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFP22253.1 - 0.0019 18.5 0.0 0.0053 17.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 KFP22253.1 - 0.023 15.1 0.7 0.023 15.1 0.7 2.6 2 0 0 2 2 2 0 Kinesin protein 1B 6PGD PF00393.19 KFP22254.1 - 2e-123 411.4 0.0 3e-123 410.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFP22254.1 - 8.5e-50 169.0 0.0 1.2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFP22254.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFP22254.1 - 0.1 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CENP-S PF15630.6 KFP22256.1 - 2e-32 111.4 0.8 3.2e-32 110.7 0.8 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFP22256.1 - 1.8e-09 37.7 0.9 2.3e-09 37.3 0.9 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFP22256.1 - 6.2e-05 23.4 0.9 6.2e-05 23.4 0.9 2.1 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFP22256.1 - 0.0088 16.0 0.3 0.021 14.8 0.2 1.7 1 1 0 2 2 2 1 Bromodomain associated TFIID-31kDa PF02291.15 KFP22256.1 - 0.023 14.8 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 KFP22256.1 - 0.053 13.5 1.0 0.073 13.1 1.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DFF-C PF09033.10 KFP22257.1 - 4.9e-64 215.2 14.6 4.9e-64 215.2 14.6 2.1 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.15 KFP22257.1 - 6.8e-18 64.5 1.1 7.9e-16 57.9 0.0 2.9 3 0 0 3 3 3 1 CIDE-N domain Amidinotransf PF02274.17 KFP22257.1 - 0.36 9.9 2.0 0.77 8.8 1.9 1.6 1 1 0 1 1 1 0 Amidinotransferase SesA PF17107.5 KFP22257.1 - 0.37 11.0 6.3 0.22 11.7 0.7 2.8 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3192 PF11399.8 KFP22257.1 - 0.62 10.0 3.9 0.81 9.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) USP8_interact PF08941.10 KFP22257.1 - 1.7 8.4 6.1 0.29 10.9 1.6 1.9 2 0 0 2 2 2 0 USP8 interacting Yuri_gagarin PF15934.5 KFP22257.1 - 2.5 7.9 13.0 0.085 12.7 5.5 2.0 2 0 0 2 2 2 0 Yuri gagarin PCRF PF03462.18 KFP22257.1 - 2.8 7.8 9.3 0.49 10.2 3.2 2.1 2 0 0 2 2 2 0 PCRF domain HR1 PF02185.16 KFP22257.1 - 3 8.0 18.4 0.76 9.9 2.8 3.0 3 1 0 3 3 3 0 Hr1 repeat Pex14_N PF04695.13 KFP22258.1 - 5.6e-22 79.1 1.9 5.6e-22 79.1 1.9 3.9 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HemX PF04375.14 KFP22258.1 - 0.00025 20.4 4.4 0.00025 20.4 4.4 1.5 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.11 KFP22258.1 - 0.0046 17.2 0.4 0.01 16.0 0.4 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) CC2-LZ PF16516.5 KFP22258.1 - 0.035 14.5 1.9 0.035 14.5 1.9 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Calici_PP_N PF08405.11 KFP22258.1 - 0.052 12.4 0.1 0.074 11.8 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal Fib_alpha PF08702.10 KFP22258.1 - 0.11 12.7 4.6 0.28 11.4 4.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GLE1 PF07817.13 KFP22258.1 - 0.2 10.9 3.3 0.3 10.3 3.3 1.2 1 0 0 1 1 1 0 GLE1-like protein Phage_Gp23 PF10669.9 KFP22258.1 - 0.93 9.8 13.5 1.1 9.6 4.7 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) TolA_bind_tri PF16331.5 KFP22258.1 - 1.6 8.9 12.0 1.9 8.6 7.4 2.7 2 1 1 3 3 3 0 TolA binding protein trimerisation Cwf_Cwc_15 PF04889.12 KFP22259.1 - 0.041 13.6 18.1 0.07 12.9 18.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KFP22259.1 - 0.098 12.2 19.2 0.18 11.4 19.2 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KFP22259.1 - 0.29 9.3 23.9 0.43 8.7 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KFP22259.1 - 8.3 6.2 20.3 14 5.5 20.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C2H2 PF00096.26 KFP22260.1 - 0.036 14.5 26.6 0.11 13.0 2.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KFP22260.1 - 0.037 14.3 13.2 3.1 8.2 2.1 3.6 1 1 2 3 3 3 0 C2H2-type zinc ribbon Fumble PF03630.14 KFP22262.1 - 0.032 13.4 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Fumble TAF6_C PF07571.13 KFP22262.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain TDP43_N PF18694.1 KFP22264.1 - 2.4e-33 113.8 0.0 4.1e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 KFP22264.1 - 8e-28 96.1 0.2 2.4e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP22264.1 - 1.8e-07 31.2 0.7 0.016 15.3 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif RL PF17797.1 KFP22264.1 - 0.00056 19.8 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 2 RL domain RRM_3 PF08777.11 KFP22264.1 - 0.00087 19.3 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KFP22264.1 - 0.0053 16.7 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 KFP22264.1 - 0.068 13.0 0.0 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) CUB PF00431.20 KFP22265.1 - 4.9e-19 68.7 0.2 7e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.6 KFP22265.1 - 4.7e-08 33.2 9.4 1.1e-07 32.0 9.4 1.7 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KFP22265.1 - 8.1e-08 32.4 7.7 1.7e-07 31.3 7.7 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.7 KFP22265.1 - 0.00034 20.5 4.0 0.00034 20.5 4.0 2.6 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.27 KFP22265.1 - 0.0008 19.7 9.7 0.0022 18.2 9.7 1.8 1 1 0 1 1 1 1 EGF-like domain hEGF PF12661.7 KFP22265.1 - 5.5 7.8 12.4 4.3 8.1 10.0 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF Spermine_synth PF01564.17 KFP22267.1 - 1.2e-64 217.2 0.0 1.9e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 KFP22267.1 - 1.2e-05 25.1 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP22267.1 - 0.00018 22.2 0.0 0.00073 20.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFP22267.1 - 0.058 13.3 0.1 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFP22267.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KFP22267.1 - 0.089 13.5 0.0 0.34 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DNA_pol_A_exo1 PF01612.20 KFP22268.1 - 9.6e-49 165.5 1.4 1.9e-48 164.5 1.4 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KFP22268.1 - 3.4e-23 82.2 0.0 2.4e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFP22268.1 - 9e-14 51.2 0.0 2.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DUF5072 PF16807.5 KFP22268.1 - 0.088 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) FAT PF02259.23 KFP22269.1 - 2.2e-128 428.3 12.7 2.2e-128 428.3 12.7 2.4 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 KFP22269.1 - 1.9e-76 257.2 0.1 3.9e-76 256.2 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KFP22269.1 - 2.5e-60 203.0 6.8 1.7e-58 197.0 0.1 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KFP22269.1 - 5.2e-46 155.1 0.4 5.2e-46 155.1 0.4 3.9 5 0 0 5 5 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 KFP22269.1 - 1.8e-12 46.8 0.1 4.8e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KFP22269.1 - 2.2e-09 37.6 9.3 0.2 12.1 0.0 8.7 11 1 1 12 12 11 3 HEAT repeats IFRD PF05004.13 KFP22269.1 - 1.2e-06 27.9 2.4 0.18 10.9 0.0 4.8 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 KFP22269.1 - 5.5e-06 26.2 20.1 10 6.7 0.1 13.3 15 0 0 15 15 14 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KFP22269.1 - 0.0021 18.6 3.0 11 6.7 0.0 6.6 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.13 KFP22269.1 - 0.0023 17.8 7.8 0.39 10.6 0.3 5.4 5 0 0 5 5 5 2 UME (NUC010) domain EPSP_synthase PF00275.20 KFP22269.1 - 0.0073 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HEAT_EZ PF13513.6 KFP22269.1 - 0.01 16.3 35.3 0.038 14.5 0.0 12.9 15 1 1 16 16 13 0 HEAT-like repeat TPR_19 PF14559.6 KFP22269.1 - 0.058 13.9 4.0 2.5 8.7 0.0 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat CFIA_Pcf11 PF11526.8 KFP22269.1 - 0.12 12.9 3.1 0.66 10.5 3.1 2.3 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 DUF1104 PF06518.11 KFP22269.1 - 4.8 7.6 6.2 32 5.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) UbiA PF01040.18 KFP22270.1 - 4.4e-41 140.9 11.7 5.5e-41 140.5 11.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Patched PF02460.18 KFP22273.1 - 1.9e-19 69.3 30.3 2.3e-16 59.1 4.1 2.7 4 0 0 4 4 4 2 Patched family MMPL PF03176.15 KFP22273.1 - 4.4e-14 52.2 30.4 2.3e-09 36.6 6.0 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KFP22273.1 - 1.4e-12 47.7 11.3 1.4e-12 47.7 11.3 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KFP22273.1 - 0.012 13.3 7.6 0.025 12.2 7.6 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FBA PF04300.13 KFP22275.1 - 1.4e-80 269.2 0.3 1.7e-80 268.9 0.3 1.1 1 0 0 1 1 1 1 F-box associated region F-box PF00646.33 KFP22275.1 - 7.6e-09 35.2 0.7 1.2e-08 34.6 0.7 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFP22275.1 - 2.4e-06 27.3 1.7 6.1e-06 26.0 1.7 1.7 1 0 0 1 1 1 1 F-box-like FBA PF04300.13 KFP22276.1 - 5e-75 251.1 0.5 6.1e-75 250.8 0.5 1.1 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.7 KFP22276.1 - 1.2e-08 34.7 5.6 3e-08 33.4 5.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP22276.1 - 1.5e-07 31.1 2.8 3.2e-07 30.0 2.8 1.6 1 0 0 1 1 1 1 F-box domain RS4NT PF08071.12 KFP22276.1 - 0.018 15.1 0.3 0.056 13.6 0.3 1.8 1 0 0 1 1 1 0 RS4NT (NUC023) domain HORMA PF02301.18 KFP22277.1 - 1.5e-09 37.8 0.1 2.7e-09 36.9 0.1 1.3 1 1 0 1 1 1 1 HORMA domain Draxin PF15550.6 KFP22278.1 - 1.9e-143 478.2 10.7 2.1e-143 478.0 10.7 1.0 1 0 0 1 1 1 1 Draxin Dickkopf_N PF04706.12 KFP22278.1 - 5 7.7 14.3 11 6.6 14.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AGTRAP PF06396.11 KFP22279.1 - 7.9e-56 188.0 5.3 8.7e-56 187.8 5.3 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) LrgB PF04172.16 KFP22279.1 - 0.0041 16.7 1.2 0.0087 15.6 0.7 1.5 1 1 0 1 1 1 1 LrgB-like family MTHFR PF02219.17 KFP22280.1 - 9.1e-110 366.5 0.0 1.2e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase SR-25 PF10500.9 KFP22280.1 - 4 7.0 9.9 6.2 6.4 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Voltage_CLC PF00654.20 KFP22281.1 - 2.9e-97 326.1 24.9 1e-96 324.3 18.4 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KFP22281.1 - 7.9e-15 55.1 0.4 2.1e-08 34.5 0.0 3.0 3 0 0 3 3 3 2 CBS domain DUF3382 PF11862.8 KFP22281.1 - 6.5 7.1 6.6 2.2 8.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) ANP PF00212.18 KFP22282.1 - 1.1e-14 54.3 9.3 1.6e-14 53.8 9.3 1.2 1 0 0 1 1 1 1 Atrial natriuretic peptide ANP PF00212.18 KFP22283.1 - 5.2e-15 55.3 9.4 9.7e-15 54.4 9.4 1.5 1 0 0 1 1 1 1 Atrial natriuretic peptide Guanylate_cyc PF00211.20 KFP22284.1 - 2.5e-69 232.6 0.0 3e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KFP22284.1 - 6.2e-05 22.5 1.5 8.5e-05 22.1 1.0 1.5 2 0 0 2 2 2 1 Heme NO binding associated Trypsin PF00089.26 KFP22285.1 - 3.7e-68 229.6 1.2 4.2e-68 229.5 1.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFP22285.1 - 7.5e-07 30.2 0.0 1.1e-06 29.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 KFP22285.1 - 0.00027 21.3 0.0 0.00065 20.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) DUF2152 PF10222.9 KFP22286.1 - 6.7e-175 582.9 0.1 7.4e-175 582.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) 2OG-FeII_Oxy PF03171.20 KFP22287.1 - 2.3e-06 28.0 0.0 5.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.14 KFP22287.1 - 2.7e-06 27.0 0.1 0.059 12.8 0.0 3.0 3 0 0 3 3 3 2 Anp1 2OG-FeII_Oxy_3 PF13640.6 KFP22287.1 - 4e-05 24.4 0.0 0.00013 22.8 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fzo_mitofusin PF04799.13 KFP22288.1 - 3.5e-75 251.0 15.1 8.6e-75 249.7 4.1 3.0 3 0 0 3 3 3 2 fzo-like conserved region Dynamin_N PF00350.23 KFP22288.1 - 2.4e-23 83.0 1.7 9e-23 81.2 0.0 2.8 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KFP22288.1 - 5.7e-08 32.8 0.0 3.8e-07 30.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase KNOX2 PF03791.13 KFP22288.1 - 0.11 12.0 0.3 4.1 7.0 0.0 3.4 4 0 0 4 4 4 0 KNOX2 domain GTP_EFTU PF00009.27 KFP22288.1 - 0.15 11.5 1.9 2.8 7.4 2.0 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Synaptobrevin PF00957.21 KFP22288.1 - 0.2 11.5 3.2 0.41 10.5 0.1 2.6 2 0 0 2 2 2 0 Synaptobrevin Apolipoprotein PF01442.18 KFP22288.1 - 0.43 10.4 11.4 0.75 9.6 4.5 2.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Streptin-Immun PF11083.8 KFP22288.1 - 1.7 9.1 5.6 0.4 11.1 0.4 2.5 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein MIIP PF15734.5 KFP22289.1 - 3.5e-46 158.3 0.9 3.8e-46 158.2 0.9 1.1 1 0 0 1 1 1 1 Migration and invasion-inhibitory TNFR_c6 PF00020.18 KFP22290.1 - 2.8e-10 40.4 44.0 5.9e-05 23.4 1.5 5.1 3 1 0 4 4 4 4 TNFR/NGFR cysteine-rich region Hus1 PF04005.12 KFP22292.1 - 0.021 13.9 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Hus1-like protein adh_short PF00106.25 KFP22293.1 - 5.9e-36 123.8 0.0 7.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP22293.1 - 3.9e-26 92.1 0.0 7.3e-26 91.2 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP22293.1 - 2.2e-17 63.5 0.0 3.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFP22293.1 - 4.8e-07 29.2 0.1 6.4e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFP22293.1 - 0.0031 17.0 0.1 0.0043 16.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFP22293.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-RING_5 PF14634.6 KFP22293.1 - 0.13 12.2 0.9 0.57 10.2 0.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Abhydrolase_3 PF07859.13 KFP22294.1 - 8.7e-47 159.7 0.0 1.3e-34 119.9 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFP22294.1 - 0.00067 18.6 0.2 0.0037 16.2 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 KFP22294.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KFP22295.1 - 2.5e-57 194.2 0.0 5.9e-44 150.5 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFP22295.1 - 4.9e-09 35.6 0.0 1.8e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KFP22295.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KFP22296.1 - 4.1e-38 131.4 0.0 1.7e-21 77.1 0.0 3.1 2 1 1 3 3 3 3 alpha/beta hydrolase fold COesterase PF00135.28 KFP22296.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family EIF_2_alpha PF07541.12 KFP22296.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Abhydrolase_3 PF07859.13 KFP22297.1 - 3.6e-42 144.6 0.0 3e-29 102.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KFP22297.1 - 0.0099 14.6 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KFP22297.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFP22297.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KFP22297.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KFP22298.1 - 1.4e-57 195.0 0.0 3e-44 151.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFP22298.1 - 2.1e-10 40.1 0.2 1.2e-09 37.7 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KFP22298.1 - 0.00034 19.6 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFP22298.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFP22298.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase LRR_8 PF13855.6 KFP22299.1 - 3.8e-34 116.2 21.5 7.6e-14 51.2 4.9 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP22299.1 - 4.8e-15 55.4 16.6 3.6e-05 24.1 0.8 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KFP22299.1 - 1.6e-10 41.0 1.6 3.6e-10 39.9 0.1 2.0 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KFP22299.1 - 2.5e-07 30.3 9.8 0.71 10.7 0.0 6.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 KFP22299.1 - 3.6e-06 26.6 3.7 8.9e-05 22.1 1.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat DUF3557 PF12078.8 KFP22299.1 - 0.0029 17.6 0.1 0.0077 16.2 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3557) LRR_3 PF07725.12 KFP22299.1 - 0.17 11.8 5.4 4.2 7.4 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRRNT PF01462.18 KFP22299.1 - 0.23 11.1 3.8 0.91 9.2 3.8 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 KFP22299.1 - 0.29 11.3 0.2 0.29 11.3 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich repeat DUF148 PF02520.17 KFP22301.1 - 0.0068 16.5 7.8 0.025 14.7 7.8 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF148 FPP PF05911.11 KFP22301.1 - 0.018 13.3 23.0 0.03 12.5 23.0 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 KFP22301.1 - 0.27 11.5 34.9 0.29 11.4 5.0 4.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KFP22301.1 - 1.6 8.6 34.6 1.1 9.1 0.1 4.6 3 1 2 5 5 5 0 Septum formation initiator ERM PF00769.19 KFP22301.1 - 2.3 8.0 43.2 0.0077 16.1 20.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KFP22301.1 - 5.1 7.1 40.7 1.5 8.8 13.2 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFP22301.1 - 6.8 5.5 34.5 6.9 5.4 14.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF5344 PF17279.2 KFP22301.1 - 9 7.0 14.7 0.75 10.4 6.9 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5344) TMEM51 PF15345.6 KFP22302.1 - 5.6e-92 307.9 0.2 6.4e-92 307.7 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM61 PF15105.6 KFP22302.1 - 3.1e-06 27.1 0.6 9.2e-05 22.3 0.0 2.7 1 1 1 3 3 3 1 TMEM61 protein family WBP-1 PF11669.8 KFP22302.1 - 0.0012 19.5 0.1 0.12 13.1 0.0 2.9 3 0 0 3 3 3 1 WW domain-binding protein 1 Shisa PF13908.6 KFP22302.1 - 0.0042 17.3 0.1 0.015 15.6 0.0 1.9 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM252 PF15664.5 KFP22302.1 - 0.007 16.1 0.6 0.028 14.1 0.0 2.2 3 0 0 3 3 3 1 Transmembrane protein 252 family FAM176 PF14851.6 KFP22302.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF4079 PF13301.6 KFP22302.1 - 0.16 12.2 0.1 0.2 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Trp_oprn_chp PF09534.10 KFP22302.1 - 0.22 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3040 PF11239.8 KFP22302.1 - 0.41 10.9 1.6 3.3 8.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) CcmD PF04995.14 KFP22302.1 - 0.86 9.7 3.3 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3899 PF13038.6 KFP22302.1 - 3.5 8.2 4.2 15 6.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) EF-hand_1 PF00036.32 KFP22304.1 - 2.2e-06 26.8 1.6 0.017 14.7 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFP22304.1 - 0.002 18.5 0.4 0.0049 17.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KFP22304.1 - 0.0042 16.9 0.1 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KFP22304.1 - 0.09 12.6 1.2 0.36 10.7 1.2 1.9 1 1 0 1 1 1 0 EF-hand domain pair Peptidase_C14 PF00656.22 KFP22305.1 - 2e-41 142.6 0.0 4.8e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 Caspase domain CARD PF00619.21 KFP22305.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain SWIM PF04434.17 KFP22305.1 - 0.0015 18.2 1.3 0.0046 16.6 1.3 1.8 1 0 0 1 1 1 1 SWIM zinc finger Thioredoxin PF00085.20 KFP22306.1 - 3.7e-09 36.5 0.0 8.1e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 KFP22306.1 - 0.025 14.6 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain IRK PF01007.20 KFP22306.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Arginase PF00491.21 KFP22307.1 - 8.3e-92 307.6 0.0 1e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KFP22307.1 - 0.12 12.6 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain Pkinase PF00069.25 KFP22308.1 - 5.6e-25 88.2 0.0 1.2e-24 87.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22308.1 - 6.6e-14 51.8 0.0 1.8e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP22308.1 - 0.00095 18.6 0.0 0.0023 17.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFP22308.1 - 0.027 14.4 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.23 KFP22309.1 - 4.6e-15 55.3 0.2 5.6e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KFP22309.1 - 5.1e-10 39.7 1.2 2.4e-07 31.0 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KFP22309.1 - 0.006 16.2 1.6 0.19 11.3 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Dynactin_p62 PF05502.13 KFP22309.1 - 0.011 14.6 0.4 0.013 14.4 0.4 1.0 1 0 0 1 1 1 0 Dynactin p62 family GIDE PF12483.8 KFP22310.1 - 1.8e-22 79.5 0.0 2.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 KFP22310.1 - 1.3e-12 47.4 14.0 2.1e-12 46.7 14.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP22310.1 - 4.7e-06 26.4 13.8 7.9e-06 25.6 13.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KFP22310.1 - 0.00022 21.5 15.4 0.00037 20.7 15.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP22310.1 - 0.0009 19.1 15.0 0.0016 18.4 15.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain LapA_dom PF06305.11 KFP22310.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2681 PF10883.8 KFP22310.1 - 0.051 14.0 0.1 0.097 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Vpu PF00558.19 KFP22310.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Vpu protein zf-C3HC4_2 PF13923.6 KFP22310.1 - 0.056 13.3 15.1 0.1 12.4 15.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4381 PF14316.6 KFP22310.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pellino PF04710.14 KFP22310.1 - 0.15 10.7 1.8 0.23 10.1 1.8 1.3 1 0 0 1 1 1 0 Pellino DEAD PF00270.29 KFP22311.1 - 4.6e-29 101.4 0.0 7.9e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP22311.1 - 1.9e-26 92.6 0.0 5.9e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP22311.1 - 7.2e-05 22.8 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CARD_2 PF16739.5 KFP22311.1 - 0.18 11.8 1.0 14 5.8 0.2 2.7 2 0 0 2 2 2 0 Caspase recruitment domain UBX PF00789.20 KFP22312.1 - 2.9e-09 37.0 0.0 6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Phospholip_A2_1 PF00068.19 KFP22313.1 - 1.5e-22 80.2 2.8 1.5e-22 80.1 2.8 1.0 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KFP22314.1 - 5.9e-20 71.8 4.0 6.2e-20 71.7 4.0 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.10 KFP22314.1 - 0.094 12.9 0.0 0.25 11.5 0.0 1.7 1 1 1 2 2 2 0 Parvovirus coat protein VP1 PsbJ PF01788.17 KFP22314.1 - 0.11 12.4 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 PsbJ Phospholip_A2_2 PF05826.12 KFP22314.1 - 0.22 11.8 5.9 0.33 11.2 5.7 1.5 1 1 0 1 1 1 0 Phospholipase A2 OTU PF02338.19 KFP22315.1 - 2.1e-07 31.5 0.0 5.6e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.6 KFP22315.1 - 0.0033 17.2 0.1 0.0054 16.5 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain DUF726 PF05277.12 KFP22316.1 - 8.8e-129 429.3 3.6 1.1e-128 429.0 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 KFP22316.1 - 0.00033 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KFP22316.1 - 0.0017 17.6 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF4710 PF15828.5 KFP22316.1 - 0.011 15.9 0.2 0.03 14.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) VirJ PF06057.11 KFP22316.1 - 0.013 15.4 0.0 0.076 12.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 KFP22316.1 - 0.044 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 KFP22316.1 - 0.15 12.1 0.1 0.37 10.9 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF3089 PF11288.8 KFP22316.1 - 0.23 11.0 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) NYD-SP28_assoc PF14775.6 KFP22316.1 - 4.9 7.3 7.0 10 6.3 4.5 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain 7tm_1 PF00001.21 KFP22317.1 - 1.9e-65 220.8 11.7 2.5e-65 220.4 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22317.1 - 1.4e-05 24.6 5.3 1.4e-05 24.6 5.3 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP22317.1 - 0.00016 21.5 8.8 0.00053 19.8 8.1 2.1 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP22317.1 - 0.0033 17.1 9.6 0.0062 16.2 9.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1385 PF07136.11 KFP22317.1 - 0.14 11.4 1.2 0.35 10.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1385) DAN PF03045.15 KFP22318.1 - 5.5e-24 84.4 7.6 7.4e-24 84.0 7.6 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.22 KFP22318.1 - 1.1e-06 28.9 6.5 1.5e-06 28.5 6.5 1.1 1 0 0 1 1 1 1 Cystine-knot domain DUF543 PF04418.12 KFP22319.1 - 8.2e-16 57.8 1.4 9.1e-16 57.6 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) F_actin_cap_B PF01115.17 KFP22320.1 - 2.4e-110 367.8 0.0 2.8e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KFP22320.1 - 0.045 13.2 0.0 0.5 9.7 0.0 2.6 1 1 0 1 1 1 0 F-actin capping protein alpha subunit PQ-loop PF04193.14 KFP22321.1 - 1.6e-28 98.3 13.5 5.5e-17 61.3 3.9 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KFP22321.1 - 0.013 15.5 9.1 0.7 10.0 0.4 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF3953 PF13129.6 KFP22321.1 - 0.13 12.0 2.5 2.9 7.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) Aldo_ket_red PF00248.21 KFP22322.1 - 3e-43 148.1 0.0 3.3e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RL10P_insert PF17777.1 KFP22323.1 - 4.1e-28 97.2 0.0 6.4e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KFP22323.1 - 6.9e-07 29.3 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 TraF PF13728.6 KFP22323.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein EMC1_C PF07774.13 KFP22324.1 - 2e-72 243.3 0.3 4.3e-72 242.3 0.1 1.7 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KFP22324.1 - 6.1e-10 39.1 0.2 1.3e-05 24.9 0.2 3.5 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KFP22324.1 - 4.5e-06 26.3 0.1 0.17 11.9 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat Filament PF00038.21 KFP22325.1 - 8.9e-20 71.5 16.7 1.3e-10 41.4 1.4 2.1 2 0 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.6 KFP22325.1 - 0.0089 16.4 1.7 0.0089 16.4 1.7 2.0 2 0 0 2 2 2 1 Snapin/Pallidin HIN PF02760.15 KFP22325.1 - 0.023 14.4 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 HIN-200/IF120x domain TMF_DNA_bd PF12329.8 KFP22325.1 - 0.031 14.3 2.4 0.031 14.3 2.4 2.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding CdvA PF18822.1 KFP22325.1 - 0.09 12.6 7.9 0.2 11.5 3.9 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Prefoldin PF02996.17 KFP22325.1 - 0.16 11.9 4.9 6.2 6.8 0.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit Glyco_hydro_56 PF01630.18 KFP22325.1 - 0.18 10.8 0.4 0.4 9.6 0.1 1.7 2 0 0 2 2 2 0 Hyaluronidase TLE_N PF03920.15 KFP22325.1 - 0.73 9.9 5.1 0.23 11.5 0.3 2.5 2 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF724 PF05266.14 KFP22325.1 - 1.5 8.6 10.2 13 5.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Rnk_N PF14760.6 KFP22325.1 - 6.9 7.2 7.2 66 4.1 2.9 3.2 3 0 0 3 3 3 0 Rnk N-terminus Aldedh PF00171.22 KFP22326.1 - 1.2e-99 333.9 0.0 1.5e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAX PF00292.18 KFP22327.1 - 1.8e-75 250.8 0.9 2.8e-75 250.2 0.9 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KFP22327.1 - 1.1e-23 82.8 7.0 2.5e-23 81.6 7.0 1.6 1 0 0 1 1 1 1 Homeodomain Pax7 PF12360.8 KFP22327.1 - 7.3e-20 70.9 6.7 1.7e-19 69.7 6.7 1.7 1 0 0 1 1 1 1 Paired box protein 7 HTH_32 PF13565.6 KFP22327.1 - 3.9e-05 24.2 6.3 0.0019 18.8 0.0 3.4 2 2 1 3 3 3 1 Homeodomain-like domain Homeobox_KN PF05920.11 KFP22327.1 - 5e-05 23.1 1.6 9e-05 22.3 0.8 1.9 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 KFP22327.1 - 9e-05 22.2 2.2 0.0012 18.6 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KFP22327.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 InsA C-terminal domain Ig_3 PF13927.6 KFP22328.1 - 2.4e-16 60.1 0.0 1.6e-06 28.6 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 KFP22328.1 - 2.6e-11 43.7 0.0 0.0032 17.8 0.0 4.5 4 1 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 KFP22328.1 - 2.1e-08 34.1 0.0 0.0051 16.8 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFP22328.1 - 4.6e-06 26.7 0.0 0.14 12.3 0.0 3.2 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP22328.1 - 0.00013 22.0 0.1 1.2 9.2 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KFP22328.1 - 0.00018 21.7 0.0 0.018 15.2 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain RhoGEF PF00621.20 KFP22329.1 - 5e-40 137.7 0.7 1.1e-39 136.6 0.4 1.7 2 0 0 2 2 2 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KFP22329.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 PH domain PAD PF03068.15 KFP22330.1 - 1.1e-144 482.2 0.0 1.4e-104 350.2 0.0 2.1 2 0 0 2 2 2 2 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFP22330.1 - 2.7e-65 218.9 0.0 4.1e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFP22330.1 - 5e-36 123.5 0.0 9.2e-36 122.7 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.15 KFP22331.1 - 5.3e-169 562.3 0.0 6.5e-169 562.0 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFP22331.1 - 8.3e-59 197.8 0.0 1.4e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFP22331.1 - 1.2e-21 77.1 0.2 2.8e-21 76.0 0.2 1.6 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.15 KFP22332.1 - 2.5e-162 540.3 0.0 3e-162 540.1 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 KFP22332.1 - 2.6e-63 212.5 0.0 4.1e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.10 KFP22332.1 - 6.9e-29 100.5 0.0 1.1e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain Fer2_3 PF13085.6 KFP22333.1 - 3.3e-24 85.0 0.0 6.7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFP22333.1 - 1.7e-09 38.0 5.4 1.7e-09 38.0 5.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFP22333.1 - 4.8e-09 36.5 20.6 3.5e-07 30.6 8.0 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFP22333.1 - 2.1e-07 31.0 2.7 2.1e-07 31.0 2.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFP22333.1 - 0.009 16.2 6.2 0.009 16.2 6.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain zf_C2H2_13 PF18508.1 KFP22333.1 - 0.014 15.0 0.6 0.085 12.5 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain Fer4_7 PF12838.7 KFP22333.1 - 0.022 15.3 12.0 0.031 14.9 7.5 2.8 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFP22333.1 - 0.033 15.1 6.5 2 9.4 1.6 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KFP22333.1 - 0.1 12.8 3.7 0.14 12.3 0.1 2.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain E1-E2_ATPase PF00122.20 KFP22334.1 - 6e-37 126.9 0.0 1.7e-36 125.5 0.0 1.6 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFP22334.1 - 7.2e-05 22.4 0.2 0.00019 21.1 0.1 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 KFP22334.1 - 0.067 12.0 1.4 0.11 11.3 1.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG MARVEL PF01284.23 KFP22334.1 - 4.9 7.2 8.4 0.7 9.9 0.9 2.3 2 1 0 2 2 2 0 Membrane-associating domain MAGP PF05507.11 KFP22335.1 - 5.3e-39 133.7 1.5 9e-39 132.9 1.5 1.3 1 0 0 1 1 1 1 Microfibril-associated glycoprotein (MAGP) ShK PF01549.24 KFP22335.1 - 0.0037 17.8 5.9 0.0037 17.8 5.9 2.2 2 1 0 2 2 2 1 ShK domain-like DUF1681 PF07933.14 KFP22336.1 - 7.4e-40 136.0 0.0 9.1e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SUZ PF12752.7 KFP22337.1 - 5.3e-13 49.5 0.1 5.3e-13 49.5 0.1 2.6 3 0 0 3 3 3 1 SUZ domain SUZ-C PF12901.7 KFP22337.1 - 1.3e-09 37.9 4.2 2.8e-09 36.8 4.2 1.6 1 0 0 1 1 1 1 SUZ-C motif Kelch_3 PF13415.6 KFP22338.1 - 6.5e-26 90.1 3.5 2.2e-08 34.2 0.1 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP22338.1 - 7.6e-26 89.9 0.5 8.5e-06 25.7 0.0 5.7 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP22338.1 - 4.1e-21 74.5 3.5 7.6e-08 32.2 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KFP22338.1 - 1.5e-18 66.1 0.2 6.5e-06 25.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KFP22338.1 - 2.9e-18 65.0 7.6 2.3e-08 33.7 0.3 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 KFP22338.1 - 3.6e-17 62.0 5.8 0.00047 20.3 0.1 5.4 4 1 1 5 5 5 4 Kelch motif F-box-like PF12937.7 KFP22338.1 - 2.4e-09 37.0 0.1 6.5e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP22338.1 - 4.1e-07 29.7 0.0 7.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KFP22338.1 - 8.8e-06 25.2 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 F-box Pkinase_Tyr PF07714.17 KFP22339.1 - 5.2e-98 327.4 0.0 6.2e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP22339.1 - 3.1e-48 164.4 0.0 4e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 KFP22339.1 - 3e-14 53.6 0.4 6.1e-14 52.7 0.4 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Haspin_kinase PF12330.8 KFP22339.1 - 0.00091 18.3 0.0 0.004 16.2 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFP22339.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Auxin_inducible PF02519.14 KFP22339.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Auxin responsive protein Pkinase_fungal PF17667.1 KFP22339.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HSP20 PF00011.21 KFP22340.1 - 4.5e-16 58.9 0.0 7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family SPOC PF07744.13 KFP22341.1 - 1.2e-24 86.9 0.1 1.4e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 SPOC domain TMEM82 PF15816.5 KFP22342.1 - 4.3e-118 393.8 15.7 4.7e-118 393.6 15.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 82 PH PF00169.29 KFP22343.1 - 9.9e-15 54.9 0.0 4.5e-12 46.4 0.0 2.8 2 0 0 2 2 2 2 PH domain RUN PF02759.19 KFP22343.1 - 3.8e-08 33.4 1.8 1e-07 32.0 1.8 1.8 1 0 0 1 1 1 1 RUN domain PH_9 PF15410.6 KFP22343.1 - 0.00059 20.2 0.0 0.049 14.0 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain hSac2 PF12456.8 KFP22343.1 - 0.1 12.3 0.1 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Inositol phosphatase UBA PF00627.31 KFP22345.1 - 0.00022 21.0 0.2 0.00039 20.3 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease PF09668.10 KFP22346.1 - 1.8e-39 134.3 1.1 2.3e-39 134.0 1.1 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFP22346.1 - 1.6e-17 63.8 0.0 5.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KFP22346.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFP22346.1 - 0.0066 17.1 0.0 0.019 15.6 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease DDOST_48kD PF03345.14 KFP22347.1 - 1.7e-142 475.2 0.0 1.9e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Linker_histone PF00538.19 KFP22348.1 - 2.1e-54 181.8 0.2 2.4e-18 66.3 0.0 3.4 3 0 0 3 3 3 3 linker histone H1 and H5 family YL1 PF05764.13 KFP22348.1 - 0.00015 22.0 17.2 0.00015 22.0 17.2 2.6 2 1 0 2 2 2 1 YL1 nuclear protein SDA1 PF05285.12 KFP22348.1 - 0.0041 16.6 41.7 0.0097 15.4 8.1 2.5 2 1 0 2 2 2 2 SDA1 BSP_II PF05432.11 KFP22348.1 - 0.012 15.4 6.7 0.012 15.4 6.7 2.8 2 1 1 3 3 3 0 Bone sialoprotein II (BSP-II) RRN3 PF05327.11 KFP22348.1 - 0.12 10.9 10.6 0.41 9.1 0.8 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KFP22348.1 - 0.19 10.0 33.1 0.058 11.7 14.1 2.3 2 0 0 2 2 2 0 CDC45-like protein Lin-8 PF03353.15 KFP22348.1 - 0.7 9.4 22.8 0.96 8.9 8.0 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 KFP22348.1 - 0.71 8.0 33.9 0.45 8.7 12.2 2.2 2 0 0 2 2 2 0 Nop14-like family SpoIIIAH PF12685.7 KFP22348.1 - 8.2 6.2 27.8 0.76 9.6 0.8 2.5 3 0 0 3 3 3 0 SpoIIIAH-like protein MIF4G PF02854.19 KFP22349.1 - 1.3e-68 230.8 8.5 2.6e-68 229.8 8.5 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KFP22349.1 - 5.3e-32 110.1 0.5 2.2e-31 108.2 0.1 2.3 2 0 0 2 2 2 1 MA3 domain W2 PF02020.18 KFP22349.1 - 9.1e-19 67.4 4.0 3.1e-18 65.7 0.8 2.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PP_kinase PF02503.17 KFP22349.1 - 0.022 14.3 1.2 0.054 13.1 1.2 1.6 1 0 0 1 1 1 0 Polyphosphate kinase middle domain DUF1476 PF07345.11 KFP22349.1 - 1.7 9.1 6.2 1.5 9.2 1.9 2.6 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Peptidase_M13_N PF05649.13 KFP22350.1 - 3.3e-126 422.0 2.1 4.1e-126 421.7 2.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KFP22350.1 - 2e-35 122.3 0.8 6.9e-35 120.5 0.2 2.2 2 0 0 2 2 2 1 Peptidase family M13 ImmE5 PF11480.8 KFP22350.1 - 0.14 12.7 0.1 0.32 11.5 0.1 1.6 1 0 0 1 1 1 0 Colicin-E5 Imm protein UCH PF00443.29 KFP22351.1 - 2.6e-41 141.8 2.4 2.6e-41 141.8 2.4 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP22351.1 - 2.1e-21 76.8 3.9 2.1e-21 76.8 3.9 3.0 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFP22351.1 - 3.5e-11 43.6 0.5 2e-06 28.3 0.0 3.9 3 1 0 3 3 3 3 DUSP domain ubiquitin PF00240.23 KFP22351.1 - 4.6e-05 23.1 0.1 0.00014 21.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Laminin_G_1 PF00054.23 KFP22352.1 - 5.2e-16 59.0 0.0 6.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFP22352.1 - 6e-14 52.7 0.0 6.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain CCDC23 PF15674.5 KFP22353.1 - 1.1e-31 108.6 12.5 1.2e-31 108.5 12.5 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 Sel1 PF08238.12 KFP22354.1 - 3.5e-65 215.0 35.3 1.1e-09 38.6 0.5 12.7 13 0 0 13 13 13 11 Sel1 repeat fn2 PF00040.19 KFP22354.1 - 7.3e-18 64.6 6.4 1.3e-17 63.7 6.4 1.5 1 0 0 1 1 1 1 Fibronectin type II domain SF3A2 PF16835.5 KFP22354.1 - 0.054 13.9 0.2 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) S6PP_C PF08472.10 KFP22354.1 - 0.15 11.9 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal SNN_linker PF09050.10 KFP22354.1 - 4.6 7.1 7.2 28 4.6 0.0 2.7 2 0 0 2 2 2 0 Stannin unstructured linker TPR_16 PF13432.6 KFP22354.1 - 5.8 7.7 10.0 9.3 7.0 0.9 4.7 3 2 0 3 3 3 0 Tetratricopeptide repeat Stonin2_N PF12016.8 KFP22355.1 - 8.4e-166 551.5 39.7 1.5e-165 550.7 39.7 1.4 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.21 KFP22355.1 - 1.3e-59 201.8 0.0 2.4e-59 200.9 0.0 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF5036 PF16439.5 KFP22356.1 - 0.029 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5036) TMF_TATA_bd PF12325.8 KFP22356.1 - 0.066 13.4 0.6 0.066 13.4 0.6 4.4 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 KFP22358.1 - 0.001 19.5 9.4 0.001 19.5 9.4 2.1 1 1 1 2 2 2 1 Centromere protein H (CENP-H) APG6_N PF17675.1 KFP22358.1 - 0.033 14.7 40.7 0.54 10.8 19.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Filament PF00038.21 KFP22358.1 - 0.048 13.2 28.2 0.057 13.0 28.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein GAS PF13851.6 KFP22358.1 - 0.056 12.8 38.2 0.024 14.0 20.8 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2235 PF09994.9 KFP22358.1 - 0.42 9.9 2.2 2.4 7.4 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_C3 PF00548.20 KFP22358.1 - 0.45 10.4 6.8 0.15 11.9 3.0 1.9 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) Tropomyosin_1 PF12718.7 KFP22358.1 - 1 9.5 39.4 0.092 12.9 31.9 2.0 1 1 1 2 2 2 0 Tropomyosin like YlqD PF11068.8 KFP22358.1 - 1.2 9.5 32.0 0.32 11.4 13.9 2.3 1 1 1 2 2 2 0 YlqD protein DUF4407 PF14362.6 KFP22358.1 - 1.5 8.1 15.3 2 7.7 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rootletin PF15035.6 KFP22358.1 - 2.6 8.0 29.6 8.3 6.4 29.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HIP1_clath_bdg PF16515.5 KFP22358.1 - 3.5 8.3 37.2 9.1 7.0 10.4 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 KFP22358.1 - 3.5 7.1 18.1 4.8 6.7 18.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit NDUFB10 PF10249.9 KFP22358.1 - 3.8 8.0 16.5 0.43 11.1 6.3 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 TPR_MLP1_2 PF07926.12 KFP22358.1 - 4.2 7.5 32.7 5 7.2 20.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EPOP PF15223.6 KFP22358.1 - 6.3 6.0 15.2 16 4.8 15.2 1.6 1 1 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein YabA PF06156.13 KFP22358.1 - 7.8 7.2 26.6 0.11 13.1 9.7 2.8 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 KFP22358.1 - 8.1 7.4 32.9 3.1 8.8 17.4 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 KFP22358.1 - 8.5 5.3 24.0 25 3.8 24.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KFP22358.1 - 9.3 4.0 17.9 12 3.7 17.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 KFP22359.1 - 1.3 9.4 11.0 3.4 8.1 4.7 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 KFP22361.1 - 0.012 15.6 3.1 0.057 13.4 3.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF2357 PF09823.9 KFP22361.1 - 0.016 14.5 0.2 0.022 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) BLOC1_2 PF10046.9 KFP22361.1 - 0.05 13.9 0.9 0.094 13.0 0.9 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T4_deiodinase PF00837.17 KFP22363.1 - 3.4e-11 42.9 0.2 3.5e-11 42.9 0.2 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Syndecan PF01034.20 KFP22364.1 - 4.3e-08 33.0 0.8 1.1e-07 31.6 0.8 1.8 1 1 0 1 1 1 1 Syndecan domain DUF202 PF02656.15 KFP22364.1 - 0.015 15.7 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) CD34_antigen PF06365.12 KFP22364.1 - 0.022 14.4 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family COX14 PF14880.6 KFP22364.1 - 0.14 12.0 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Orf78 PF06024.12 KFP22364.1 - 2.9 8.2 4.6 0.64 10.4 0.3 1.9 1 1 1 2 2 2 0 Orf78 (ac78) Laminin_G_2 PF02210.24 KFP22365.1 - 2.5e-16 60.4 0.1 3.6e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KFP22365.1 - 1.3e-05 25.4 0.2 2.1e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 Laminin G domain Na_trans_cytopl PF11933.8 KFP22365.1 - 0.089 12.6 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel DUF3439 PF11921.8 KFP22365.1 - 0.29 11.1 5.3 0.47 10.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ABC1 PF03109.16 KFP22372.1 - 8.6e-40 135.6 0.3 1.5e-39 134.8 0.3 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KFP22372.1 - 2e-06 27.4 0.0 0.00024 20.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFP22372.1 - 0.00084 19.3 0.2 0.17 11.8 0.2 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family SKIP_SNW PF02731.15 KFP22373.1 - 2.5e-74 248.3 7.6 2.5e-74 248.3 7.6 2.2 2 0 0 2 2 2 1 SKIP/SNW domain SIR4_SID PF16991.5 KFP22373.1 - 0.37 10.8 3.1 0.87 9.6 3.1 1.6 1 0 0 1 1 1 0 Sir4 SID domain RRM_1 PF00076.22 KFP22374.1 - 6.2e-11 42.0 0.0 7.2e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3860 PF12976.7 KFP22374.1 - 0.087 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) 2OG-FeII_Oxy_2 PF13532.6 KFP22375.1 - 8.5e-38 130.5 0.0 2.1e-37 129.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4462 PF14692.6 KFP22376.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Aminotran_1_2 PF00155.21 KFP22377.1 - 1.3e-60 205.6 0.0 1.5e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFP22377.1 - 0.0015 17.6 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFP22377.1 - 0.0044 16.3 0.0 0.0071 15.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFP22377.1 - 0.19 10.3 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Vps16_C PF04840.12 KFP22378.1 - 5.4e-10 38.8 1.3 0.00045 19.4 0.2 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region DUF3105 PF11303.8 KFP22378.1 - 0.092 12.9 0.1 4.3 7.5 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3105) FliX PF10768.9 KFP22379.1 - 0.043 14.3 0.2 0.051 14.1 0.2 1.1 1 0 0 1 1 1 0 Class II flagellar assembly regulator GOLD_2 PF13897.6 KFP22380.1 - 1.3e-70 236.2 1.3 2e-70 235.6 1.3 1.3 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking RGI_lyase PF18370.1 KFP22380.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 Rhamnogalacturonan I lyases beta-sheet domain GST_N_3 PF13417.6 KFP22381.1 - 1.3e-17 63.9 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFP22381.1 - 2e-15 56.9 0.0 4.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFP22381.1 - 6.1e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFP22381.1 - 5.5e-08 32.9 0.0 8.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP22381.1 - 0.00038 20.6 0.0 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFP22381.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFP22381.1 - 0.025 14.9 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Glutaredoxin PF00462.24 KFP22381.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin GST_C_5 PF16865.5 KFP22381.1 - 0.089 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PMT PF02366.18 KFP22382.1 - 2.2e-80 269.8 13.9 3.8e-80 269.0 13.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFP22382.1 - 1.6e-55 187.8 4.6 1.6e-55 187.8 4.6 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFP22382.1 - 1.6e-22 80.3 0.1 2.4e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 MIR domain Globin PF00042.22 KFP22383.1 - 1.3e-10 41.8 0.0 3.2e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Globin RSN1_7TM PF02714.15 KFP22384.1 - 6.4e-59 199.5 28.1 6.4e-59 199.5 28.1 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFP22384.1 - 4.7e-50 170.2 0.4 6.6e-50 169.8 0.4 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFP22384.1 - 1e-23 83.9 2.9 1e-23 83.9 2.9 5.3 5 2 1 6 6 6 2 Late exocytosis, associated with Golgi transport DHHC PF01529.20 KFP22385.1 - 3.7e-21 75.6 8.5 3.7e-21 75.6 8.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase InaF-motif PF15018.6 KFP22385.1 - 0.11 12.4 3.6 0.26 11.2 3.6 1.6 1 0 0 1 1 1 0 TRP-interacting helix CiPC PF15800.5 KFP22386.1 - 3.2e-110 369.1 9.5 3.8e-110 368.8 9.5 1.1 1 0 0 1 1 1 1 Clock interacting protein circadian TMEM219 PF14940.6 KFP22388.1 - 0.071 12.7 0.2 0.072 12.7 0.2 1.0 1 0 0 1 1 1 0 Transmembrane 219 Exo_endo_phos PF03372.23 KFP22389.1 - 4.8e-39 134.3 0.0 7.3e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vasohibin PF14822.6 KFP22390.1 - 4.2e-99 330.7 0.0 4.9e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Vasohibin Hormone_recep PF00104.30 KFP22391.1 - 6.4e-31 107.6 0.6 1e-30 106.9 0.6 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP22391.1 - 6.9e-31 106.5 12.3 1.3e-30 105.7 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) IFT43 PF15305.6 KFP22394.1 - 4.7e-44 149.9 3.1 6e-44 149.5 3.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 TGF_beta PF00019.20 KFP22395.1 - 2.4e-24 86.3 1.0 4.1e-24 85.6 1.0 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 KFP22395.1 - 1.3e-20 74.2 0.0 1.7e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TTL PF03133.15 KFP22396.1 - 1.8e-90 303.0 0.0 4.7e-90 301.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFP22396.1 - 7.3e-08 32.0 0.0 0.00091 18.5 0.0 2.8 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KFP22396.1 - 0.00078 18.8 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp XkdW PF09636.10 KFP22396.1 - 0.002 18.2 0.9 0.94 9.6 0.2 2.9 2 0 0 2 2 2 2 XkdW protein Erg28 PF03694.13 KFP22397.1 - 3.9e-09 36.9 4.7 5.1e-09 36.5 4.7 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF1427 PF07235.11 KFP22397.1 - 0.054 13.4 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) MFS_1 PF07690.16 KFP22398.1 - 7.4e-28 97.5 46.4 1.1e-25 90.4 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM210 PF15195.6 KFP22398.1 - 0.042 14.3 0.6 0.27 11.6 0.2 2.2 2 0 0 2 2 2 0 TMEM210 family DUF4212 PF13937.6 KFP22398.1 - 5.5 7.4 9.0 1.3 9.4 0.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) SYS1 PF09801.9 KFP22398.1 - 5.6 7.1 11.7 0.089 12.9 1.6 2.7 3 1 0 3 3 3 0 Integral membrane protein S linking to the trans Golgi network bZIP_1 PF00170.21 KFP22399.1 - 2.5e-11 43.5 9.0 3.1e-11 43.2 9.0 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP22399.1 - 5.2e-10 39.3 12.4 6e-10 39.0 12.4 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP22399.1 - 1.9e-07 31.5 8.2 2.3e-07 31.2 8.2 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 KFP22399.1 - 0.016 15.4 2.1 0.016 15.4 2.1 1.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper TMCO5 PF14992.6 KFP22399.1 - 0.016 14.8 2.8 0.018 14.7 2.8 1.0 1 0 0 1 1 1 0 TMCO5 family Phlebovirus_NSM PF07246.11 KFP22399.1 - 0.024 14.0 3.7 0.027 13.8 3.7 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M APG6_N PF17675.1 KFP22399.1 - 0.12 12.9 6.0 0.16 12.5 6.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region CtIP_N PF10482.9 KFP22399.1 - 0.16 12.1 5.4 0.21 11.7 5.4 1.1 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain SlyX PF04102.12 KFP22399.1 - 0.16 12.6 3.8 0.13 12.8 1.3 1.9 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 KFP22399.1 - 1.8 8.4 7.5 0.57 10.0 3.6 1.8 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KFP22400.1 - 9.3e-11 41.7 21.8 1.3e-10 41.2 21.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP22400.1 - 3.8e-08 33.3 22.4 5.4e-08 32.8 22.4 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP22400.1 - 1.3e-07 32.0 13.6 1.8e-07 31.6 13.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.9 KFP22400.1 - 0.12 10.9 10.7 0.14 10.7 10.7 1.0 1 0 0 1 1 1 0 Macoilin family VGCC_beta4Aa_N PF12052.8 KFP22400.1 - 8.7 6.5 12.1 0.73 10.0 5.2 2.3 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal EMP24_GP25L PF01105.24 KFP22401.1 - 8.9e-37 126.8 0.0 1.1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD zf-C2HC_2 PF13913.6 KFP22402.1 - 1.3e-15 56.9 11.2 9.5e-08 31.8 2.5 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KFP22402.1 - 0.0011 19.0 3.5 0.035 14.2 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger domain zf-CpG_bind_C PF12269.8 KFP22402.1 - 0.072 12.9 2.7 7.5 6.3 1.1 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-C2HC5 PF06221.13 KFP22402.1 - 0.074 13.1 1.5 1.8 8.6 0.7 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF4720 PF15846.5 KFP22402.1 - 0.081 12.8 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) zf-H2C2_2 PF13465.6 KFP22402.1 - 0.09 13.2 5.3 2.9 8.5 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Nairovirus_M PF07948.11 KFP22402.1 - 0.091 11.0 0.3 0.15 10.2 0.3 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zinc_ribbon_9 PF14369.6 KFP22402.1 - 0.15 12.3 2.6 0.61 10.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_4 PF13894.6 KFP22402.1 - 0.29 12.1 10.4 3.1 8.9 0.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFP22402.1 - 0.39 11.1 4.9 2.3 8.6 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFP22402.1 - 2.4 8.8 7.7 8.6 7.0 0.0 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C4_ClpX PF06689.13 KFP22402.1 - 5 7.1 6.9 11 6.0 3.0 2.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger Acylphosphatase PF00708.18 KFP22403.1 - 3.8e-14 52.8 0.0 4.6e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase MutL_C PF08676.11 KFP22404.1 - 1.6e-11 44.2 0.3 5e-11 42.6 0.3 1.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFP22404.1 - 4.7e-11 42.4 0.0 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KFP22404.1 - 2.4e-08 34.4 0.1 1.5e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFP22404.1 - 6.8e-08 32.4 0.1 1.9e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF-2B PF01008.17 KFP22405.1 - 7e-82 274.8 0.1 7.9e-82 274.6 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PDGF PF00341.17 KFP22406.1 - 5.6e-26 90.6 4.6 6.4e-26 90.5 4.6 1.0 1 0 0 1 1 1 1 PDGF/VEGF domain Pkinase PF00069.25 KFP22407.1 - 5.6e-26 91.5 0.0 1.6e-24 86.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22407.1 - 6.8e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 KFP22407.1 - 0.0079 16.2 1.4 0.015 15.3 1.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain APH PF01636.23 KFP22407.1 - 0.13 12.2 1.9 0.22 11.4 1.9 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.23 KFP22409.1 - 9.2e-81 270.7 0.2 1.1e-80 270.4 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFP22409.1 - 2.5e-22 78.5 0.5 4.4e-22 77.7 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFP22409.1 - 0.0034 17.2 0.0 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.19 KFP22409.1 - 0.15 12.0 0.8 0.33 10.9 0.8 1.6 1 1 0 1 1 1 0 Glycine cleavage H-protein AAA_33 PF13671.6 KFP22410.1 - 1.8e-09 37.9 0.1 5.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 KFP22410.1 - 0.00031 20.1 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 KFP22410.1 - 0.00094 18.5 0.1 0.0053 16.0 0.1 2.0 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 KFP22410.1 - 0.0019 17.7 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KFP22410.1 - 0.0078 16.8 0.0 0.028 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Fcf1 PF04900.12 KFP22411.1 - 9.5e-40 135.0 2.3 1.2e-39 134.6 2.3 1.1 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFP22411.1 - 3.2e-11 43.6 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 KFP22411.1 - 0.059 13.7 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 NTF2 fold immunity protein HECT PF00632.25 KFP22412.1 - 3.9e-74 249.9 0.1 6.3e-74 249.2 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 KFP22412.1 - 5.4e-11 43.2 0.2 1.1e-06 29.3 0.0 3.6 3 1 0 3 3 3 2 Filamin/ABP280 repeat EGF_CA PF07645.15 KFP22413.1 - 1e-96 316.9 260.3 6.7e-09 35.8 5.7 20.1 20 0 0 20 20 20 17 Calcium-binding EGF domain cEGF PF12662.7 KFP22413.1 - 1.9e-65 216.3 162.8 5.6e-09 35.8 1.8 20.2 20 0 0 20 20 20 17 Complement Clr-like EGF-like TB PF00683.17 KFP22413.1 - 1e-43 146.8 83.7 3.1e-16 58.9 7.0 7.6 7 1 0 7 7 7 4 TB domain EGF PF00008.27 KFP22413.1 - 6.2e-28 96.7 260.3 0.00053 20.2 5.7 22.2 21 1 1 22 22 22 15 EGF-like domain hEGF PF12661.7 KFP22413.1 - 3.7e-12 46.4 253.0 0.00027 21.5 5.5 24.0 25 0 0 25 25 25 14 Human growth factor-like EGF FXa_inhibition PF14670.6 KFP22413.1 - 2.4e-10 40.5 272.4 0.004 17.4 7.7 21.5 17 3 4 21 21 21 14 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 KFP22413.1 - 1.7e-09 37.7 200.9 0.0013 18.9 1.6 20.4 19 1 0 19 19 19 11 EGF domain Plasmod_Pvs28 PF06247.11 KFP22413.1 - 1.3 9.4 170.3 0.16 12.3 4.2 17.8 16 1 1 17 17 17 0 Pvs28 EGF domain E1_DerP2_DerF2 PF02221.15 KFP22414.1 - 7.8e-22 78.1 0.0 8.3e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 ML domain Cu-oxidase_3 PF07732.15 KFP22414.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Multicopper oxidase Fe-S_biosyn PF01521.20 KFP22415.1 - 2.7e-08 34.0 0.0 7.3e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis CD225 PF04505.12 KFP22416.1 - 8.8e-18 64.2 0.2 1.5e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein HTH_Tnp_1 PF01527.20 KFP22417.1 - 6.9e-07 29.5 7.7 0.019 15.2 0.1 4.7 5 0 0 5 5 5 3 Transposase HTH_Tnp_1_2 PF13022.6 KFP22417.1 - 1.7e-06 28.2 1.5 2 8.6 0.1 4.3 4 0 0 4 4 4 2 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 KFP22417.1 - 8.5e-05 22.2 7.3 0.55 10.1 0.0 4.6 5 0 0 5 5 5 2 Homeodomain-like domain DUF1492 PF07374.11 KFP22417.1 - 9e-05 22.6 2.4 1.7 8.9 0.0 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1492) Cnl2_NKP2 PF09447.10 KFP22417.1 - 0.035 14.3 1.6 5.9 7.1 0.0 3.6 3 0 0 3 3 3 0 Cnl2/NKP2 family protein OTU PF02338.19 KFP22417.1 - 0.036 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 OTU-like cysteine protease Cbl_N2 PF02761.14 KFP22417.1 - 0.041 14.6 0.4 6.6 7.5 0.0 3.3 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Creb_binding PF09030.10 KFP22417.1 - 0.07 13.8 0.1 0.26 12.0 0.1 2.0 1 0 0 1 1 1 0 Creb binding HTH_29 PF13551.6 KFP22417.1 - 0.094 12.7 0.5 5.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn helix HTH_28 PF13518.6 KFP22417.1 - 0.12 12.5 8.5 7.9 6.7 0.0 5.0 5 0 0 5 5 5 0 Helix-turn-helix domain ABC_membrane_2 PF06472.15 KFP22418.1 - 1.4e-72 244.4 2.3 1.9e-72 243.9 2.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFP22418.1 - 5.5e-17 62.6 0.0 9.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KFP22418.1 - 0.00027 20.7 0.0 0.0008 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain SbmA_BacA PF05992.12 KFP22418.1 - 0.0039 16.7 1.7 0.0061 16.0 1.7 1.4 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_16 PF13191.6 KFP22418.1 - 0.0088 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFP22418.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFP22418.1 - 0.031 13.8 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KFP22418.1 - 0.034 14.4 0.5 0.14 12.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain IRK PF01007.20 KFP22418.1 - 0.052 13.4 1.0 0.094 12.5 1.0 1.4 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DEAD PF00270.29 KFP22418.1 - 0.11 12.2 0.0 0.66 9.7 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 KFP22418.1 - 0.19 11.6 0.4 0.35 10.7 0.4 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KFP22418.1 - 0.25 11.8 0.2 0.49 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KFP22418.1 - 0.26 11.5 0.7 1 9.6 0.3 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AMP-binding_C PF13193.6 KFP22419.1 - 7.2e-17 62.1 0.2 9.5e-17 61.8 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFP22419.1 - 4.2e-10 38.8 0.1 9.8e-10 37.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding PF00501.28 KFP22420.1 - 8.9e-20 70.7 0.0 9.6e-20 70.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1967 PF09269.11 KFP22420.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) LIN52 PF10044.9 KFP22421.1 - 1.6e-17 64.0 0.0 1.7e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Retinal tissue protein Aldedh PF00171.22 KFP22422.1 - 6.6e-122 407.3 0.0 7.5e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFP22422.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF4515 PF14988.6 KFP22423.1 - 5.2e-16 59.1 41.4 5.2e-16 59.1 41.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4515) Peptidase_M24_C PF16188.5 KFP22423.1 - 0.21 11.7 2.3 0.74 9.9 0.4 2.8 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 AAA_lid_8 PF17868.1 KFP22423.1 - 2.8 7.9 9.4 0.35 10.8 0.2 3.8 4 1 0 4 4 4 0 AAA lid domain GDA1_CD39 PF01150.17 KFP22424.1 - 6.3e-78 262.3 0.0 2.7e-77 260.3 0.0 1.8 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FAD_binding_3 PF01494.19 KFP22425.1 - 1.4e-18 67.3 0.1 5.5e-11 42.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KFP22425.1 - 0.00014 21.0 0.0 0.00034 19.7 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 KFP22425.1 - 0.13 11.1 0.0 0.7 8.7 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase UPF0564 PF10595.9 KFP22426.1 - 7.9e-75 252.2 41.3 1.1e-74 251.8 41.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 zf-H2C2_2 PF13465.6 KFP22427.1 - 1.4e-23 82.2 31.4 1.8e-06 28.1 0.3 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KFP22427.1 - 3.4e-23 80.7 26.7 2.8e-05 24.3 0.1 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFP22427.1 - 2.5e-14 52.8 28.1 0.0012 19.5 4.0 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFP22427.1 - 3.5e-05 23.5 13.4 0.4 10.5 0.1 3.7 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFP22427.1 - 7.6e-05 22.5 8.5 0.21 11.5 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KFP22427.1 - 9.1e-05 22.7 7.8 0.012 15.9 1.5 3.5 2 1 3 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KFP22427.1 - 0.00013 22.2 7.9 2.1 8.5 0.1 4.3 1 1 3 4 4 4 2 Aberrant zinc-finger zf-met PF12874.7 KFP22427.1 - 0.0018 18.6 7.5 0.94 10.0 0.1 4.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP22427.1 - 0.015 15.6 8.5 2.4 8.5 0.0 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 KFP22427.1 - 0.092 12.8 1.0 6.4 6.8 0.0 2.9 2 1 1 3 3 3 0 CpXC protein CHORD PF04968.12 KFP22427.1 - 0.21 12.3 13.4 4.4 8.1 0.1 4.9 2 1 3 5 5 5 0 CHORD zf-DNA_Pol PF08996.10 KFP22427.1 - 0.5 10.1 3.6 6.8 6.4 0.1 2.5 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KFP22427.1 - 0.6 10.2 31.1 6.2 6.9 0.2 6.0 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFP22427.1 - 0.85 10.0 9.8 0.49 10.8 1.0 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) SH3_2 PF07653.17 KFP22429.1 - 1.1e-09 37.8 0.0 2.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain NPIP PF06409.11 KFP22429.1 - 6.4e-07 28.7 10.7 0.0027 16.8 9.1 2.6 2 0 0 2 2 2 2 Nuclear pore complex interacting protein (NPIP) DUF1664 PF07889.12 KFP22429.1 - 0.0097 15.9 8.1 0.0097 15.9 8.1 4.7 3 2 2 5 5 5 2 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KFP22429.1 - 0.012 16.0 10.7 0.012 16.0 10.7 6.9 4 2 1 6 6 6 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 KFP22429.1 - 4.6 7.7 35.7 0.084 13.3 3.7 5.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Pinin_SDK_memA PF04696.13 KFP22430.1 - 4.4e-34 117.3 20.7 4.4e-34 117.3 20.7 5.7 5 2 1 6 6 6 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.13 KFP22430.1 - 3.7e-29 102.1 3.7 3.7e-29 102.1 3.7 5.1 4 2 0 5 5 5 1 pinin/SDK conserved region Mucin PF01456.17 KFP22430.1 - 7.1 6.6 16.9 17 5.3 16.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein TRAPP PF04051.16 KFP22431.1 - 3.2e-33 114.5 0.1 3.6e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SIP1 PF04938.12 KFP22432.1 - 6.7e-69 231.9 0.4 7.6e-69 231.8 0.4 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Sec23_trunk PF04811.15 KFP22433.1 - 1.5e-79 267.0 0.0 2.1e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFP22433.1 - 3.1e-33 114.4 0.0 6.9e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFP22433.1 - 1.1e-27 95.9 0.1 2.7e-27 94.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KFP22433.1 - 2.7e-15 56.0 0.0 8.6e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KFP22433.1 - 2.7e-15 56.1 6.7 5.1e-15 55.2 6.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger APP_E2 PF12925.7 KFP22433.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein 7tm_1 PF00001.21 KFP22436.1 - 1.6e-63 214.5 27.3 2e-63 214.2 27.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22436.1 - 5.7e-14 52.1 24.0 7.1e-14 51.8 24.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22436.1 - 6.1e-10 39.2 23.1 2.4e-09 37.2 23.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KFP22436.1 - 9.4e-09 35.0 15.3 9.4e-09 35.0 15.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP22436.1 - 0.00029 20.7 22.9 0.00062 19.6 22.9 1.6 1 1 0 1 1 1 1 Olfactory receptor Piezo_RRas_bdg PF12166.8 KFP22436.1 - 0.0036 16.6 0.9 0.13 11.5 0.1 2.3 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain T2SSM PF04612.12 KFP22436.1 - 0.075 13.1 0.2 0.075 13.1 0.2 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M COX7C PF02935.16 KFP22436.1 - 0.34 11.2 8.1 0.51 10.6 0.3 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc DUF3995 PF13160.6 KFP22436.1 - 1.2 9.5 10.5 7.3 7.0 3.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) MCR_D PF02505.14 KFP22437.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D RVT_1 PF00078.27 KFP22438.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_1 PF00515.28 KFP22439.1 - 9.8e-64 208.8 56.2 4.9e-06 26.1 0.1 17.9 18 1 0 18 18 18 13 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22439.1 - 3.9e-58 188.9 35.1 2.3e-06 27.3 0.0 18.0 17 1 0 17 17 17 13 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22439.1 - 3.2e-45 151.5 23.1 3.4e-06 26.6 1.8 13.9 9 4 5 14 14 14 9 TPR repeat TPR_8 PF13181.6 KFP22439.1 - 1.7e-36 121.3 41.3 8.2e-06 25.6 0.0 16.2 18 1 0 18 18 17 9 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22439.1 - 3.6e-36 123.1 2.1 9.4e-06 25.7 0.0 9.1 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22439.1 - 2.7e-27 93.1 21.1 0.00029 21.0 0.9 12.2 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22439.1 - 2.1e-26 92.3 1.4 0.00033 21.2 0.0 9.4 4 3 5 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22439.1 - 6.4e-23 80.8 27.6 4.4e-05 23.7 0.0 12.1 8 4 4 12 12 12 7 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22439.1 - 5.3e-21 73.5 2.4 0.18 12.7 0.0 13.2 5 4 10 15 15 15 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22439.1 - 6.4e-16 58.6 15.1 0.00037 20.9 0.0 9.1 4 2 6 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22439.1 - 3.6e-11 42.3 13.5 0.08 13.0 0.0 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP22439.1 - 8e-11 42.0 31.7 0.0012 19.0 2.1 7.2 6 2 2 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP22439.1 - 1e-10 41.5 31.6 1.9 9.3 0.0 12.9 16 0 0 16 16 13 3 Tetratricopeptide repeat TPR_15 PF13429.6 KFP22439.1 - 1.4e-08 34.3 1.5 0.13 11.5 0.0 6.2 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP22439.1 - 0.0001 22.0 18.3 2 8.4 0.0 9.5 11 0 0 11 11 11 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP22439.1 - 0.00044 20.3 10.0 0.046 13.8 0.0 5.6 6 0 0 6 6 4 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KFP22439.1 - 0.0032 16.9 12.9 0.16 11.5 0.0 7.1 9 0 0 9 9 9 1 SHNi-TPR ANAPC5 PF12862.7 KFP22439.1 - 0.012 15.7 11.5 5.5 7.1 0.1 5.8 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 CHCH PF06747.13 KFP22439.1 - 0.015 15.4 3.9 0.018 15.2 0.2 3.2 4 0 0 4 4 2 0 CHCH domain TPR_20 PF14561.6 KFP22439.1 - 0.032 14.6 0.7 28 5.1 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 KFP22439.1 - 0.052 13.3 4.9 20 4.8 0.0 4.8 3 2 1 5 5 5 0 Tetratricopeptide repeat-like domain zf_CopZ PF18423.1 KFP22439.1 - 0.64 10.0 5.3 11 6.1 0.1 3.6 4 0 0 4 4 4 0 Zinc binding domain CPG4 PF15481.6 KFP22439.1 - 0.77 10.4 5.3 0.25 12.0 0.9 2.6 2 0 0 2 2 1 0 Chondroitin proteoglycan 4 RPN7 PF10602.9 KFP22439.1 - 6.9 6.3 14.6 1.1 8.9 1.0 4.6 5 2 1 6 6 5 0 26S proteasome subunit RPN7 NPBW PF15180.6 KFP22440.1 - 4.8 7.1 6.5 2.3 8.1 0.7 2.7 2 1 1 3 3 3 0 Neuropeptides B and W Mito_carr PF00153.27 KFP22441.1 - 6.7e-46 154.2 1.2 9.7e-15 54.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Homeodomain PF00046.29 KFP22442.1 - 1.9e-20 72.4 4.8 3.4e-20 71.6 4.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFP22442.1 - 0.081 12.8 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Sds3 PF08598.11 KFP22444.1 - 6.4e-25 88.4 8.6 5.6e-24 85.4 10.0 1.5 1 1 1 2 2 2 1 Sds3-like Borrelia_P83 PF05262.11 KFP22444.1 - 0.54 8.7 7.0 0.76 8.2 7.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Rap_GAP PF02145.15 KFP22445.1 - 3.7e-46 157.0 0.0 1.1e-45 155.5 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Ank_2 PF12796.7 KFP22446.1 - 4.3e-27 94.5 5.0 1.7e-14 54.1 0.5 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP22446.1 - 5.6e-27 93.0 9.0 5.9e-07 29.6 0.2 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP22446.1 - 4.2e-26 90.7 4.6 3.7e-10 39.8 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP22446.1 - 1.3e-23 80.5 4.7 7e-06 26.0 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFP22446.1 - 9.8e-21 73.9 2.1 7.9e-09 35.9 0.2 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) CRR7 PF12095.8 KFP22446.1 - 0.035 14.5 0.3 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Proteasome PF00227.26 KFP22449.1 - 1.9e-53 180.8 0.2 2.1e-53 180.6 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit PRORP PF16953.5 KFP22450.1 - 4.9e-94 314.4 2.2 4.9e-94 314.4 1.2 1.5 2 0 0 2 2 2 1 Protein-only RNase P PPR_2 PF13041.6 KFP22450.1 - 4.8e-09 36.3 1.8 0.076 13.2 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 KFP22450.1 - 1.2e-05 25.2 10.0 0.053 13.8 0.1 4.7 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 KFP22450.1 - 0.00072 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 KFP22450.1 - 0.0079 16.0 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Baculo_VP39 PF04501.12 KFP22450.1 - 0.027 14.0 0.1 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Baculovirus major capsid protein VP39 Rad50_zn_hook PF04423.14 KFP22450.1 - 0.082 12.8 0.1 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif EF-hand_7 PF13499.6 KFP22451.1 - 6.5e-09 36.1 7.2 5.8e-05 23.5 0.1 5.0 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KFP22451.1 - 1.9e-06 27.3 3.5 0.51 10.4 0.1 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_13 PF17958.1 KFP22451.1 - 8e-06 25.6 0.1 4.8e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KFP22451.1 - 9.1e-05 21.7 0.4 0.26 10.9 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KFP22451.1 - 0.027 13.9 0.9 0.13 11.8 0.0 2.7 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 KFP22451.1 - 0.03 14.2 0.0 5 7.0 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain pair FAM177 PF14774.6 KFP22452.1 - 4.4e-28 98.0 0.1 4.4e-28 98.0 0.1 1.9 1 1 1 2 2 2 1 FAM177 family DUF719 PF05334.13 KFP22452.1 - 0.0003 21.1 0.1 0.00037 20.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF719) PAF PF15715.5 KFP22452.1 - 0.0013 19.3 2.5 0.0015 19.2 2.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Connexin PF00029.19 KFP22452.1 - 0.0037 17.0 0.3 0.0041 16.9 0.3 1.2 1 0 0 1 1 1 1 Connexin ZapB PF06005.12 KFP22452.1 - 0.016 15.7 7.1 0.023 15.1 7.1 1.2 1 0 0 1 1 1 0 Cell division protein ZapB CPSF100_C PF13299.6 KFP22452.1 - 0.062 13.5 0.8 0.071 13.3 0.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SRP54 PF00448.22 KFP22453.1 - 1.7e-77 259.5 0.4 7.3e-77 257.4 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFP22453.1 - 2.4e-30 105.1 2.7 2.4e-30 105.1 2.7 3.2 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFP22453.1 - 1e-20 73.7 3.1 3.4e-20 72.1 3.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFP22453.1 - 3.4e-07 30.0 0.7 3.3e-06 26.8 0.5 2.4 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFP22453.1 - 6.4e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFP22453.1 - 3e-05 24.1 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2209 PF09974.9 KFP22453.1 - 0.00016 22.0 0.3 0.00044 20.6 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) SRPRB PF09439.10 KFP22453.1 - 0.00025 20.5 0.5 0.62 9.5 0.0 2.7 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KFP22453.1 - 0.0007 19.9 0.5 0.0066 16.7 0.1 2.7 3 1 0 3 3 2 1 AAA domain MeaB PF03308.16 KFP22453.1 - 0.0018 17.3 0.0 0.041 12.9 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFP22453.1 - 0.0043 16.8 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KFP22453.1 - 0.0059 16.5 0.6 0.023 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFP22453.1 - 0.0062 16.6 2.0 0.017 15.2 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KFP22453.1 - 0.0099 16.3 1.1 0.0099 16.3 1.1 3.0 3 1 0 3 3 1 1 AAA domain ResIII PF04851.15 KFP22453.1 - 0.01 15.9 0.5 0.028 14.4 0.5 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit GTP_EFTU PF00009.27 KFP22453.1 - 0.011 15.2 0.4 0.095 12.2 0.4 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP22453.1 - 0.015 15.7 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KFP22453.1 - 0.022 14.6 0.6 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 KFP22453.1 - 0.024 14.4 1.3 0.18 11.5 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KFP22453.1 - 0.027 14.4 0.4 0.1 12.5 0.0 2.2 2 1 1 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KFP22453.1 - 0.031 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KFP22453.1 - 0.033 14.7 0.1 0.11 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KFP22453.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 KFP22453.1 - 0.045 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFP22453.1 - 0.049 14.1 1.9 0.46 10.9 0.2 3.2 2 2 1 3 3 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KFP22453.1 - 0.05 12.8 0.4 0.33 10.1 0.3 2.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KFP22453.1 - 0.065 12.9 0.3 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 KFP22453.1 - 0.08 12.7 0.4 0.86 9.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YlbD_coat PF14071.6 KFP22453.1 - 6.9 6.9 11.6 14 6.0 3.2 4.5 2 1 2 4 4 4 0 Putative coat protein Methyltransf_11 PF08241.12 KFP22454.1 - 2.7e-05 24.7 0.1 6.6e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 KFP22454.1 - 8.7e-05 22.1 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 KFP22454.1 - 0.00011 22.9 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFP22454.1 - 0.00021 21.9 0.1 0.00051 20.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFP22454.1 - 0.0054 16.5 0.1 0.0095 15.7 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DOT1 PF08123.13 KFP22454.1 - 0.023 14.2 1.8 0.26 10.8 1.8 2.3 1 1 0 1 1 1 0 Histone methylation protein DOT1 YdfZ PF14001.6 KFP22454.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 YdfZ protein WSD PF15613.6 KFP22456.1 - 7.2e-30 103.4 0.0 7.2e-30 103.4 0.0 4.8 4 3 0 4 4 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 KFP22456.1 - 9e-25 87.1 0.0 9e-25 87.1 0.0 4.1 4 0 0 4 4 3 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.25 KFP22456.1 - 2.1e-20 72.6 0.4 4.3e-20 71.6 0.4 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KFP22456.1 - 4.1e-14 52.2 5.8 9.1e-14 51.1 5.8 1.6 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 KFP22456.1 - 1.1e-09 38.5 2.4 1.1e-09 38.5 2.4 2.9 3 0 0 3 3 2 1 DDT domain WHIM1 PF15612.6 KFP22456.1 - 3.2e-09 36.1 0.0 9.9e-09 34.5 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.6 KFP22456.1 - 0.06 13.3 2.4 0.17 11.8 2.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 KFP22456.1 - 0.07 13.4 1.7 0.31 11.3 1.7 2.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 KFP22456.1 - 0.1 12.9 3.0 0.27 11.5 3.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 KFP22456.1 - 0.11 12.6 2.0 0.41 10.8 2.0 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 KFP22456.1 - 0.47 10.8 5.4 0.95 9.8 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain Cofilin_ADF PF00241.20 KFP22457.1 - 2.3e-33 114.5 0.9 3.1e-33 114.1 0.9 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PX PF00787.24 KFP22458.1 - 5.8e-18 64.9 0.6 8.7e-15 54.7 0.6 3.3 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 KFP22458.1 - 7.6e-14 51.8 14.7 7.7e-12 45.3 11.7 2.7 2 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.18 KFP22458.1 - 2.5e-05 24.0 16.2 0.00071 19.3 9.7 2.7 3 1 0 3 3 3 2 BAR domain IF3_C PF00707.22 KFP22458.1 - 0.0028 17.6 0.3 0.069 13.1 0.1 2.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Q_salvage PF10343.9 KFP22458.1 - 0.0047 16.5 1.0 0.0072 15.9 0.3 1.5 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family Eapp_C PF10238.9 KFP22459.1 - 2.5e-51 173.7 7.6 2.5e-51 173.7 7.6 2.4 2 1 0 2 2 2 1 E2F-associated phosphoprotein C1_4 PF07975.12 KFP22459.1 - 0.018 15.2 2.0 0.058 13.6 0.4 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 KFP22459.1 - 0.033 14.4 1.3 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Yippee-Mis18 PF03226.14 KFP22459.1 - 0.34 11.1 6.1 0.87 9.8 6.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly 2OG-FeII_Oxy_3 PF13640.6 KFP22460.1 - 1.9e-15 57.5 0.0 2.1e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KFP22460.1 - 7.5e-09 36.1 0.0 7.7e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAS_3 PF08447.12 KFP22462.1 - 2.4e-24 85.4 0.2 1e-18 67.4 0.2 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFP22462.1 - 7.9e-13 48.5 0.0 4e-09 36.6 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFP22462.1 - 5.3e-11 42.5 0.0 1.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFP22462.1 - 2.9e-08 33.9 0.0 0.00013 22.2 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KFP22462.1 - 0.00043 20.5 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KFP22464.1 - 2.5e-05 24.2 0.6 3.2e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RhoGAP PF00620.27 KFP22467.1 - 1e-47 161.7 0.9 1.9e-47 160.9 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain RhoGAP-FF1 PF16512.5 KFP22467.1 - 5.6e-30 103.8 14.1 2.4e-28 98.6 6.7 4.3 4 0 0 4 4 4 1 p190-A and -B Rho GAPs FF domain FF PF01846.19 KFP22467.1 - 5.1e-14 52.2 10.0 7.5e-10 38.8 1.3 4.5 4 0 0 4 4 4 3 FF domain Ras PF00071.22 KFP22467.1 - 9.6e-14 51.3 3.8 4.9e-05 23.0 0.3 4.5 4 0 0 4 4 4 4 Ras family AAA_22 PF13401.6 KFP22467.1 - 0.0021 18.4 0.1 2.1 8.6 0.1 3.0 2 0 0 2 2 2 2 AAA domain NOG1 PF06858.14 KFP22467.1 - 0.0062 16.3 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.27 KFP22467.1 - 0.0094 15.5 0.2 0.032 13.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KFP22467.1 - 0.018 15.3 0.1 0.81 9.9 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase U5_2-snRNA_bdg PF10597.9 KFP22467.1 - 0.095 12.8 0.9 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 MMR_HSR1 PF01926.23 KFP22467.1 - 0.11 12.6 0.0 0.77 9.9 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase SR-25 PF10500.9 KFP22467.1 - 1.5 8.4 13.7 3.7 7.1 13.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ParA PF10609.9 KFP22468.1 - 3.1e-97 324.9 1.2 3.6e-97 324.7 1.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFP22468.1 - 2.7e-11 43.6 0.0 7.2e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFP22468.1 - 1.5e-08 34.8 0.2 2.3e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KFP22468.1 - 8.2e-07 28.6 0.0 1.5e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFP22468.1 - 2e-05 23.9 0.6 0.00071 18.8 0.3 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KFP22468.1 - 0.00044 19.8 0.7 0.0029 17.1 0.7 2.2 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KFP22468.1 - 0.0015 18.2 0.3 0.0038 16.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain VirC1 PF07015.11 KFP22468.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein Tyr_Deacylase PF02580.16 KFP22469.1 - 2.6e-30 105.8 0.0 2.9e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HEAT PF02985.22 KFP22470.1 - 2.8e-10 39.6 34.4 0.027 14.7 1.0 10.9 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 KFP22470.1 - 4.6e-10 39.8 13.2 1.3 9.4 0.1 8.9 7 1 2 9 9 9 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KFP22470.1 - 0.00032 21.2 0.0 0.01 16.4 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFP22470.1 - 0.0031 18.0 30.5 0.21 12.2 0.9 9.4 9 0 0 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 KFP22470.1 - 0.013 15.6 4.5 2.8 8.0 0.0 5.7 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 OSCP PF00213.18 KFP22470.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Clat_adaptor_s PF01217.20 KFP22472.1 - 7.5e-38 129.7 8.1 8.4e-38 129.5 8.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PHD_like PF12910.7 KFP22472.1 - 0.02 14.9 0.8 0.027 14.5 0.8 1.2 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system WD40 PF00400.32 KFP22473.1 - 2.1e-36 123.3 10.5 3e-08 34.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.12 KFP22473.1 - 5.8e-27 95.2 2.7 5.8e-27 95.2 2.7 2.7 2 1 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 KFP22473.1 - 5.5e-08 33.0 0.2 0.11 12.9 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFP22473.1 - 9.9e-05 21.2 0.2 0.79 8.3 0.0 3.4 4 0 0 4 4 4 2 Nucleoporin Nup120/160 VWA PF00092.28 KFP22474.1 - 9.8e-82 273.4 0.0 4.7e-42 144.2 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KFP22474.1 - 6.6e-27 94.3 0.0 3.5e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.19 KFP22474.1 - 1.1e-22 79.9 0.1 2.8e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 LCCL domain VWA_3 PF13768.6 KFP22474.1 - 0.00017 21.6 0.0 0.092 12.7 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Rxt3 PF08642.10 KFP22474.1 - 0.15 12.9 0.0 0.48 11.2 0.0 1.8 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Sec1 PF00995.23 KFP22475.1 - 6.7e-123 411.9 1.1 7.5e-123 411.8 1.1 1.0 1 0 0 1 1 1 1 Sec1 family cwf21 PF08312.12 KFP22475.1 - 0.085 13.0 0.1 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 cwf21 domain zf-HC5HC2H PF13771.6 KFP22476.1 - 3.1e-19 69.0 4.1 3.1e-19 69.0 4.1 4.1 3 1 0 3 3 3 1 PHD-like zinc-binding domain HECT PF00632.25 KFP22476.1 - 2.9e-09 36.8 0.0 6.8e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-HC5HC2H_2 PF13832.6 KFP22476.1 - 1.5e-07 31.5 4.8 1.5e-07 31.5 4.8 4.1 2 2 2 5 5 5 1 PHD-zinc-finger like domain OLF PF02191.16 KFP22477.1 - 2e-83 279.8 8.3 3.2e-83 279.1 8.3 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain BRICHOS PF04089.14 KFP22478.1 - 3.5e-21 75.3 0.0 1e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 BRICHOS domain SGS PF05002.15 KFP22479.1 - 9.9e-34 115.3 2.4 9.9e-34 115.3 2.4 2.1 3 0 0 3 3 3 1 SGS domain CS PF04969.16 KFP22479.1 - 1.2e-18 67.9 2.6 1.4e-18 67.6 1.5 1.8 2 0 0 2 2 1 1 CS domain TPR_2 PF07719.17 KFP22479.1 - 2.9e-08 33.2 9.4 1e-05 25.2 2.7 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22479.1 - 2.2e-07 30.4 11.5 7.4e-06 25.6 3.6 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22479.1 - 6.7e-07 29.3 3.8 0.0048 17.2 0.5 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22479.1 - 1.5e-05 24.8 2.5 0.00046 20.2 1.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22479.1 - 0.0045 17.7 1.1 0.066 14.1 0.4 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22479.1 - 0.0065 16.1 7.1 0.74 9.6 0.9 2.9 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 KFP22479.1 - 0.027 15.1 2.7 0.1 13.3 1.6 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP22479.1 - 0.058 13.6 2.1 0.099 12.9 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP22479.1 - 0.058 13.7 3.2 0.75 10.1 3.6 2.2 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF2018 PF09442.10 KFP22479.1 - 0.064 14.2 0.1 0.21 12.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) TPR_20 PF14561.6 KFP22479.1 - 0.092 13.1 3.1 1 9.8 1.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP22479.1 - 7.8 6.7 6.3 14 5.9 1.2 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Elf-1_N PF12310.8 KFP22480.1 - 5e-36 123.6 4.3 8.4e-36 122.9 1.0 2.5 2 0 0 2 2 2 1 Transcription factor protein N terminal Ets PF00178.22 KFP22480.1 - 2.2e-34 117.8 1.0 3.5e-34 117.1 1.0 1.3 1 0 0 1 1 1 1 Ets-domain WW PF00397.26 KFP22481.1 - 5.2e-20 71.2 17.8 8.9e-10 38.5 4.5 2.7 2 0 0 2 2 2 2 WW domain zf-U1 PF06220.12 KFP22481.1 - 5.6e-15 54.8 0.7 9.2e-15 54.1 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger Glyco_hyd_101C PF17451.2 KFP22481.1 - 0.0038 17.5 15.8 0.1 12.9 0.6 3.1 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain ATF7IP_BD PF16788.5 KFP22481.1 - 0.011 15.9 5.6 0.011 15.9 5.6 3.3 1 1 1 3 3 3 0 ATF-interacting protein binding domain PQQ PF01011.21 KFP22481.1 - 0.063 13.2 0.2 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat PCRF PF03462.18 KFP22482.1 - 9.3e-51 172.4 1.1 9.3e-51 172.4 1.1 2.3 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KFP22482.1 - 1.8e-38 131.0 3.5 1.8e-38 131.0 3.5 2.2 2 0 0 2 2 2 1 RF-1 domain HisKA PF00512.25 KFP22482.1 - 0.0057 16.7 5.4 0.43 10.7 0.2 3.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain SPOB_a PF14689.6 KFP22482.1 - 0.04 13.6 0.3 2.3 8.0 0.0 2.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF3475 PF11961.8 KFP22482.1 - 0.22 11.6 1.2 1 9.5 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3475) CDI PF02234.19 KFP22482.1 - 0.26 11.5 2.6 0.72 10.1 0.0 3.0 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor DUF4635 PF15466.6 KFP22482.1 - 0.26 10.8 7.7 6.8 6.2 2.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) DUF445 PF04286.12 KFP22482.1 - 5.3 6.7 10.8 5.7 6.6 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF5101 PF17031.5 KFP22482.1 - 6 7.0 10.5 0.24 11.5 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5101) NARP1 PF12569.8 KFP22483.1 - 4.3e-222 738.6 20.7 4.3e-222 738.6 20.7 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KFP22483.1 - 3.1e-18 64.3 23.4 4.4e-05 23.3 0.1 8.6 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22483.1 - 4.1e-16 58.3 3.2 0.1 13.5 0.0 9.6 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22483.1 - 2.4e-13 49.3 28.5 2e-05 24.2 0.6 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22483.1 - 7e-13 47.7 23.9 0.00028 20.8 0.2 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22483.1 - 5.3e-11 42.0 8.3 8.3e-06 25.4 0.1 5.9 5 0 0 5 5 5 2 TPR repeat TPR_16 PF13432.6 KFP22483.1 - 6.7e-10 39.5 8.7 0.0048 17.5 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22483.1 - 1.2e-09 38.5 11.0 0.041 14.4 0.3 6.2 4 1 2 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP22483.1 - 2.7e-09 37.1 18.3 0.00023 21.3 0.5 6.2 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFP22483.1 - 1.7e-08 34.6 14.1 1.5 9.1 0.1 7.7 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22483.1 - 5.2e-06 26.1 12.8 0.071 13.2 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP22483.1 - 5.5e-06 25.8 1.7 5.5e-06 25.8 1.7 3.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22483.1 - 0.00027 21.0 7.4 0.52 10.5 0.2 5.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP22483.1 - 0.0037 17.1 7.6 31 4.6 0.1 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-N PF05238.13 KFP22483.1 - 0.011 15.1 2.0 0.017 14.5 2.0 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like TPR_4 PF07721.14 KFP22483.1 - 0.016 15.7 0.0 1.7e+02 3.3 0.1 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22483.1 - 0.022 15.1 15.0 0.76 10.3 0.1 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF789 PF05623.12 KFP22483.1 - 0.061 13.0 2.5 0.13 11.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) TPR_21 PF09976.9 KFP22483.1 - 0.12 12.0 0.0 0.12 12.0 0.0 3.8 5 1 0 5 5 4 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KFP22483.1 - 0.18 12.5 12.4 32 5.4 0.1 6.4 7 1 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP22483.1 - 0.32 11.1 24.0 9.4 6.4 0.2 7.1 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_S49_N PF08496.10 KFP22483.1 - 3.2 7.8 10.0 9.3 6.3 10.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RVT_1 PF00078.27 KFP22490.1 - 0.0011 18.5 0.0 0.0027 17.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KFP22492.1 - 1.7e-82 271.9 7.0 1.8e-18 66.8 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP22492.1 - 6.2e-55 185.5 1.5 1.3e-54 184.4 0.6 1.9 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 KFP22492.1 - 6.4e-12 45.5 2.2 0.0051 16.8 0.0 5.1 5 0 0 5 5 5 4 Cadherin-like Cadherin_2 PF08266.12 KFP22492.1 - 5e-05 23.0 0.0 1.1 9.1 0.0 4.4 4 0 0 4 4 4 1 Cadherin-like Cadherin_4 PF17803.1 KFP22492.1 - 0.039 14.6 0.8 0.039 14.6 0.8 4.4 4 0 0 4 4 4 0 Bacterial cadherin-like domain ASFV_J13L PF05568.11 KFP22492.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein PepSY PF03413.19 KFP22492.1 - 0.15 12.7 2.5 2.3 8.8 0.3 3.7 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain Invasin_D3 PF09134.10 KFP22492.1 - 3.1 8.2 12.0 14 6.0 0.0 4.6 5 1 1 6 6 6 0 Invasin, domain 3 Cadherin PF00028.17 KFP22499.1 - 2e-83 274.9 5.6 3.2e-19 69.1 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.17 KFP22499.1 - 1.8e-57 193.8 1.1 3.4e-57 192.8 1.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.12 KFP22499.1 - 1e-06 28.5 0.0 0.078 12.8 0.0 3.9 4 0 0 4 4 4 2 Cadherin-like Stevor PF17410.2 KFP22499.1 - 0.0098 15.5 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame ASFV_J13L PF05568.11 KFP22499.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Sigma_1s PF02454.16 KFP22499.1 - 0.052 13.5 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Sigma 1s protein Y_Y_Y PF07495.13 KFP22499.1 - 0.1 12.6 0.0 27 4.8 0.0 3.8 4 0 0 4 4 4 0 Y_Y_Y domain VirB3 PF05101.13 KFP22499.1 - 0.2 11.9 0.4 0.37 11.0 0.4 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein RIFIN PF02009.16 KFP22499.1 - 0.32 10.8 0.8 0.56 10.0 0.8 1.3 1 0 0 1 1 1 0 Rifin RVT_1 PF00078.27 KFP22505.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4462 PF14692.6 KFP22506.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) 7tm_4 PF13853.6 KFP22507.1 - 7.4e-48 163.7 11.7 8.6e-48 163.5 11.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22507.1 - 2.6e-32 112.2 13.6 4e-32 111.6 13.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22507.1 - 1e-05 25.1 11.0 1.8e-05 24.2 11.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22507.1 - 0.022 14.4 13.5 0.045 13.4 12.2 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CholecysA-Rec_N PF09193.10 KFP22507.1 - 0.14 12.2 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal DUF1240 PF06836.12 KFP22507.1 - 1.5 9.4 9.2 0.21 12.2 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) 7tm_4 PF13853.6 KFP22509.1 - 2.7e-46 158.5 13.6 3.2e-46 158.3 13.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22509.1 - 1.3e-30 106.6 12.7 1.9e-30 106.1 12.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22509.1 - 0.00014 21.3 10.2 0.00021 20.8 10.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22509.1 - 0.0011 18.6 3.5 0.0011 18.6 3.5 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP22510.1 - 8.9e-48 163.4 13.7 1e-47 163.2 13.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22510.1 - 9.6e-30 103.8 16.3 1.6e-29 103.0 16.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22511.1 - 1.5e-47 162.7 15.1 1.7e-47 162.5 15.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22511.1 - 2.3e-30 105.8 14.3 3.2e-30 105.3 14.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.10 KFP22511.1 - 0.039 13.9 0.3 0.77 9.8 0.0 2.7 3 0 0 3 3 3 0 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFP22512.1 - 1.7e-49 169.1 12.7 2e-49 168.8 12.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22512.1 - 7.2e-30 104.2 16.1 9.5e-30 103.8 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22512.1 - 0.00016 21.2 13.5 0.00026 20.5 13.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RAMP4 PF06624.12 KFP22512.1 - 0.16 12.0 2.0 0.38 10.9 2.0 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 7tm_4 PF13853.6 KFP22513.1 - 1.7e-45 155.9 12.2 2e-45 155.7 12.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22513.1 - 2.2e-30 105.9 10.9 3.6e-30 105.2 10.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22513.1 - 2.6e-05 23.8 11.3 4.1e-05 23.1 11.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP22514.1 - 3.3e-48 164.8 17.1 3.8e-48 164.6 17.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22514.1 - 1e-30 107.0 19.4 1.4e-30 106.5 19.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22514.1 - 0.0095 15.3 18.1 0.014 14.8 18.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP22515.1 - 6.5e-46 157.3 11.7 7.5e-46 157.1 11.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22515.1 - 8.7e-30 103.9 14.1 1.3e-29 103.3 14.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22515.1 - 0.0086 15.5 12.1 0.0051 16.2 9.7 1.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4519 PF15012.6 KFP22515.1 - 0.47 10.6 1.1 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 7tm_4 PF13853.6 KFP22516.1 - 3.7e-20 72.8 3.2 4e-20 72.7 3.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22516.1 - 0.0027 17.1 6.0 0.0034 16.7 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2417 PF10329.9 KFP22516.1 - 0.56 9.6 2.4 0.61 9.5 2.4 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) 7tm_4 PF13853.6 KFP22517.1 - 7.2e-25 88.3 3.1 8.4e-25 88.0 3.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22517.1 - 0.00013 21.4 5.4 0.00018 20.9 5.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22518.1 - 8.6e-29 101.1 13.8 9.6e-19 68.2 4.1 2.1 1 1 1 2 2 2 2 Olfactory receptor 7tm_1 PF00001.21 KFP22518.1 - 2.7e-20 72.8 11.1 7.8e-20 71.3 2.6 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22518.1 - 0.01 15.3 2.9 0.01 15.3 2.9 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP22519.1 - 7.8e-13 48.8 0.4 8.4e-13 48.7 0.4 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_4 PF13853.6 KFP22520.1 - 8.9e-48 163.4 12.3 1e-47 163.2 12.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22520.1 - 4.7e-29 101.5 12.5 6.3e-29 101.1 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22520.1 - 9.6e-07 28.4 7.6 9.6e-07 28.4 7.6 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22520.1 - 0.032 13.9 10.3 0.015 15.0 6.8 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP22521.1 - 6.7e-32 111.3 5.1 7.5e-32 111.2 5.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22521.1 - 1.7e-14 53.8 7.3 2.3e-14 53.4 7.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 KFP22521.1 - 0.039 13.3 1.8 0.067 12.5 1.8 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 KFP22522.1 - 2.4e-22 80.0 4.4 2.7e-22 79.8 4.4 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22522.1 - 2.3e-05 23.8 7.9 3e-05 23.5 7.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Myc_target_1 PF15179.6 KFP22522.1 - 0.069 13.1 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 Myc target protein 1 Rax2 PF12768.7 KFP22522.1 - 0.098 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity 7tm_4 PF13853.6 KFP22523.1 - 1.9e-42 145.9 13.1 2.3e-42 145.7 13.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22523.1 - 1.1e-31 110.1 13.6 1.5e-31 109.7 13.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22525.1 - 3.7e-43 148.3 11.9 4.1e-43 148.1 11.9 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22525.1 - 2e-27 96.2 16.2 2.8e-27 95.7 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP22525.1 - 0.036 13.7 9.7 0.18 11.4 9.7 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP22526.1 - 4e-49 167.8 7.6 4.7e-49 167.6 7.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22526.1 - 1.7e-29 103.0 8.6 2.7e-29 102.3 8.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22526.1 - 0.088 12.2 7.8 0.011 15.1 2.7 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx HTH_9 PF08221.11 KFP22527.1 - 3.8e-06 26.9 0.8 8e-06 25.9 0.7 1.6 1 1 1 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain zf-RING_2 PF13639.6 KFP22528.1 - 2.8e-13 50.0 7.8 2.8e-13 50.0 7.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP22528.1 - 8.1e-09 35.2 7.7 8.1e-09 35.2 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP22528.1 - 4.2e-08 32.8 3.1 4.2e-08 32.8 3.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFP22528.1 - 1.5e-07 31.4 4.5 4.4e-07 29.8 2.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFP22528.1 - 1.3e-06 28.6 8.8 1.3e-06 28.6 8.8 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP22528.1 - 1.9e-06 27.7 5.7 1.9e-06 27.7 5.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP22528.1 - 3.1e-06 27.0 6.8 3.1e-06 27.0 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP22528.1 - 2e-05 24.4 3.3 2e-05 24.4 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFP22528.1 - 8e-05 22.6 6.5 0.00032 20.7 3.6 2.7 3 1 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFP22528.1 - 0.0028 17.5 10.6 0.012 15.5 8.0 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KFP22528.1 - 0.0059 16.8 7.2 0.0063 16.8 0.6 3.1 3 0 0 3 3 3 1 zinc-ribbon zf-Nse PF11789.8 KFP22528.1 - 0.032 14.1 3.8 0.069 13.0 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.6 KFP22528.1 - 0.15 12.3 2.4 0.12 12.6 0.6 1.7 1 1 1 2 2 2 0 PHD-zinc-finger like domain Rad50_zn_hook PF04423.14 KFP22528.1 - 0.15 11.9 7.6 0.46 10.3 0.3 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 KFP22528.1 - 0.15 11.9 3.1 0.53 10.2 3.1 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.6 KFP22528.1 - 0.19 12.0 3.0 0.14 12.5 0.6 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-H2C2_2 PF13465.6 KFP22528.1 - 0.45 11.0 6.2 39 4.9 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Opy2 PF09463.10 KFP22528.1 - 0.48 10.8 6.5 21 5.5 0.3 3.2 3 0 0 3 3 3 0 Opy2 protein Vps39_2 PF10367.9 KFP22528.1 - 0.49 10.9 3.0 4.5 7.8 0.9 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-ribbon_3 PF13248.6 KFP22528.1 - 0.61 9.6 3.4 23 4.5 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.6 KFP22528.1 - 0.63 9.9 8.6 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain HypA PF01155.19 KFP22528.1 - 0.65 10.0 2.9 1.7 8.7 1.1 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KFP22528.1 - 0.7 10.2 13.4 15 6.0 8.4 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF983 PF06170.12 KFP22528.1 - 0.73 10.3 3.8 18 5.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Baculo_IE-1 PF05290.11 KFP22528.1 - 1.2 9.1 4.2 1.5 8.7 1.5 2.2 2 1 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 KFP22528.1 - 1.4 9.0 4.8 7.2 6.7 1.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KFP22528.1 - 2.5 8.1 6.4 33 4.6 0.9 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn_ribbon_17 PF17120.5 KFP22528.1 - 3.9 7.2 10.2 0.15 11.7 4.3 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type TF_Zn_Ribbon PF08271.12 KFP22528.1 - 4.3 6.9 7.5 16 5.1 0.2 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding PHD PF00628.29 KFP22528.1 - 4.5 7.2 9.9 12 5.9 5.2 2.8 2 1 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 KFP22528.1 - 4.6 7.3 6.6 10 6.2 3.0 2.4 2 1 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.6 KFP22528.1 - 6.9 6.7 9.0 7.6 6.5 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.6 KFP22528.1 - 8.7 6.4 7.8 9 6.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RRM_1 PF00076.22 KFP22529.1 - 6.8e-19 67.5 0.0 1.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFP22529.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KFP22529.1 - 5.5e-05 22.8 0.0 7.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Enolase_C PF00113.22 KFP22530.1 - 3.6e-159 528.7 0.0 4.6e-159 528.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFP22530.1 - 1.8e-60 202.8 0.1 3.2e-60 202.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFP22530.1 - 4.7e-08 32.9 0.0 6.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFP22530.1 - 0.0019 17.4 0.9 0.0029 16.8 0.3 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Atrophin-1 PF03154.15 KFP22531.1 - 0 1592.9 171.5 0 1306.8 123.7 2.1 1 1 1 2 2 2 2 Atrophin-1 family ELM2 PF01448.24 KFP22531.1 - 1.7e-14 54.3 0.1 1.8e-13 51.0 0.0 2.7 2 0 0 2 2 2 1 ELM2 domain GATA PF00320.27 KFP22531.1 - 4.6e-11 42.1 2.6 9.2e-11 41.2 2.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 KFP22531.1 - 4.6e-05 23.5 0.3 0.00011 22.3 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFP22531.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.2 3 0 0 3 3 3 0 Myb DNA-binding like SAM_1 PF00536.30 KFP22532.1 - 7e-12 45.6 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP22532.1 - 9.1e-11 41.7 0.3 2.5e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KFP22532.1 - 0.0039 17.4 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 KFP22532.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Noc2 PF03715.13 KFP22533.1 - 8.8e-125 415.9 9.7 8.8e-125 415.9 9.7 1.7 2 0 0 2 2 2 1 Noc2p family Kelch_1 PF01344.25 KFP22534.1 - 3.4e-79 260.2 15.3 3.8e-16 58.4 0.3 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFP22534.1 - 1.6e-44 148.8 3.7 2.3e-09 37.2 0.0 6.5 1 1 5 6 6 6 6 Kelch motif BACK PF07707.15 KFP22534.1 - 1.8e-38 130.7 0.2 4e-38 129.6 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 KFP22534.1 - 1.2e-33 115.6 0.6 2.4e-33 114.6 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KFP22534.1 - 1.5e-27 95.3 1.2 2.7e-06 27.3 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP22534.1 - 3.4e-27 94.2 15.7 7.7e-07 29.3 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KFP22534.1 - 4.8e-26 89.7 2.0 0.00013 21.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KFP22534.1 - 4.9e-09 36.0 5.5 0.1 12.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif BA14K PF07886.11 KFP22534.1 - 0.034 14.0 2.0 0.76 9.7 0.0 3.7 4 0 0 4 4 4 0 BA14K-like protein XPA_C PF05181.12 KFP22534.1 - 0.12 12.4 0.2 27 4.8 0.0 2.7 2 0 0 2 2 2 0 XPA protein C-terminus PQQ_3 PF13570.6 KFP22534.1 - 3.1 8.4 13.0 22 5.7 0.1 5.7 6 0 0 6 6 6 0 PQQ-like domain SH2 PF00017.24 KFP22535.1 - 5.5e-26 90.5 0.0 7.4e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 KFP22535.1 - 0.048 13.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 SH2 domain Y_phosphatase PF00102.27 KFP22536.1 - 5e-34 117.9 0.0 5.7e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP22536.1 - 4.5e-06 26.5 0.1 9.5e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP22536.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFP22536.1 - 0.00094 19.2 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family UPF0254 PF06787.11 KFP22536.1 - 0.013 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) zf-RING_5 PF14634.6 KFP22537.1 - 3.3e-09 36.6 6.4 3.3e-09 36.6 6.4 2.0 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP22537.1 - 4.8e-09 36.4 6.8 4.8e-09 36.4 6.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP22537.1 - 4.6e-08 32.9 7.7 4.7e-08 32.9 5.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP22537.1 - 1.4e-06 28.1 4.1 1.4e-06 28.1 4.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP22537.1 - 3.9e-06 26.6 7.0 3.9e-06 26.6 7.0 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFP22537.1 - 3.6e-05 23.8 7.1 0.00019 21.5 7.1 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFP22537.1 - 0.00016 21.3 5.0 0.00036 20.2 5.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFP22537.1 - 0.0031 17.3 10.6 0.0031 17.3 10.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UBM PF14377.6 KFP22537.1 - 0.016 14.6 0.3 0.031 13.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin binding region zf-RING_4 PF14570.6 KFP22537.1 - 0.027 14.3 5.7 0.027 14.3 5.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFP22537.1 - 0.21 11.9 6.4 1.3 9.3 6.4 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFP22537.1 - 0.59 10.3 7.5 6 7.1 5.1 2.8 2 1 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KFP22537.1 - 6.8 6.6 17.5 0.046 13.6 7.4 2.7 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 DUF4501 PF14946.6 KFP22538.1 - 6.5e-30 104.5 0.8 6.9e-30 104.4 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) Sid-5 PF17204.3 KFP22538.1 - 0.13 12.5 0.4 0.14 12.3 0.4 1.1 1 0 0 1 1 1 0 Sid-5 family PH PF00169.29 KFP22539.1 - 0.0025 18.3 0.0 0.0035 17.8 0.0 1.3 1 0 0 1 1 1 1 PH domain TNFR_c6 PF00020.18 KFP22541.1 - 2.2e-06 27.9 0.4 2.2e-06 27.9 0.4 3.2 3 1 0 3 3 3 2 TNFR/NGFR cysteine-rich region TNFR_c6 PF00020.18 KFP22542.1 - 1.4e-16 60.6 25.5 2.6e-07 30.9 9.5 3.3 3 0 0 3 3 3 3 TNFR/NGFR cysteine-rich region RANK_CRD_2 PF18278.1 KFP22542.1 - 0.0031 17.6 2.8 0.0031 17.6 2.8 1.9 1 1 1 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Ephrin_rec_like PF07699.13 KFP22542.1 - 0.49 10.2 20.0 1.5 8.6 2.2 2.6 2 1 0 2 2 2 0 Putative ephrin-receptor like EF-hand_1 PF00036.32 KFP22543.1 - 3.4e-20 70.0 10.3 0.00045 19.6 0.0 6.6 7 0 0 7 7 7 5 EF hand EF-hand_7 PF13499.6 KFP22543.1 - 6.6e-15 55.3 17.4 4.8e-07 30.1 0.1 5.1 2 2 4 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 KFP22543.1 - 9.8e-13 46.9 1.8 0.38 10.8 0.0 5.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 KFP22543.1 - 1.3e-12 46.6 2.1 0.0015 17.9 0.0 5.2 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KFP22543.1 - 7.2e-09 35.4 6.7 0.0032 17.3 0.0 5.2 4 2 1 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFP22543.1 - 0.00027 21.2 14.4 0.13 12.6 0.9 3.5 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Pex14_N PF04695.13 KFP22543.1 - 0.0085 16.8 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Galactosyl_T PF01762.21 KFP22544.1 - 6.3e-21 75.1 0.0 9e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase C1q PF00386.21 KFP22545.1 - 2.9e-06 27.5 0.0 8.2e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 C1q domain Collagen PF01391.18 KFP22545.1 - 0.0029 17.3 4.3 0.0045 16.7 4.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.18 KFP22545.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family UQ_con PF00179.26 KFP22546.1 - 1.2e-18 67.1 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ASC PF00858.24 KFP22547.1 - 7.4e-107 358.1 12.3 8.6e-107 357.8 12.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel BAR_3 PF16746.5 KFP22548.1 - 3.7e-75 252.7 10.3 6.2e-75 252.0 10.3 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 KFP22548.1 - 5.6e-41 139.3 0.5 2.1e-40 137.5 0.5 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KFP22548.1 - 3.1e-14 53.3 0.2 3.1e-14 53.3 0.2 2.0 2 0 0 2 2 1 1 PH domain Ank_2 PF12796.7 KFP22548.1 - 4.3e-08 33.6 0.4 2.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP22548.1 - 2.7e-07 31.0 0.5 0.31 11.7 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP22548.1 - 3.2e-06 27.3 1.1 0.0067 16.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) BAR PF03114.18 KFP22548.1 - 0.0027 17.4 5.7 0.0053 16.4 5.7 1.4 1 0 0 1 1 1 1 BAR domain PH_11 PF15413.6 KFP22548.1 - 0.012 16.1 5.0 0.096 13.1 2.5 2.8 2 1 0 2 2 1 0 Pleckstrin homology domain Ank_3 PF13606.6 KFP22548.1 - 0.032 14.8 0.5 64 4.6 0.0 4.6 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 KFP22548.1 - 0.078 13.5 4.1 9.7 6.8 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeat Exonuc_VII_L PF02601.15 KFP22548.1 - 0.081 12.5 1.9 0.16 11.5 1.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PH_8 PF15409.6 KFP22548.1 - 0.1 12.9 0.1 0.39 11.0 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain PseudoU_synth_1 PF01416.20 KFP22549.1 - 1.8e-36 124.9 0.1 6.1e-28 97.4 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase Beta-Casp PF10996.8 KFP22550.1 - 9.8e-26 90.2 0.0 3.1e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KFP22550.1 - 2.6e-23 82.5 0.0 5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KFP22550.1 - 2.1e-20 72.4 0.1 4.3e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KFP22550.1 - 4.4e-11 43.1 0.1 1.8e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFP22550.1 - 1.2e-09 37.9 0.5 1.2e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFP22550.1 - 0.00024 21.0 0.1 0.0018 18.2 0.0 2.5 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Dsh_C PF12316.8 KFP22551.1 - 3.2e-72 243.3 26.8 3.2e-72 243.3 26.8 2.3 3 0 0 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal PDZ PF00595.24 KFP22551.1 - 8.5e-20 70.9 0.3 1.4e-19 70.2 0.3 1.4 1 0 0 1 1 1 1 PDZ domain Dishevelled PF02377.15 KFP22551.1 - 4.5e-17 63.0 20.3 4.5e-17 63.0 20.3 2.9 3 0 0 3 3 3 1 Dishevelled specific domain DEP PF00610.21 KFP22551.1 - 1.3e-16 60.4 0.1 2.4e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KFP22551.1 - 3.6e-05 23.5 0.1 6.1e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP22551.1 - 0.0021 18.4 0.2 0.0042 17.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.12 KFP22551.1 - 0.027 13.9 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Dishevelled PF02377.15 KFP22552.1 - 3.2e-10 40.7 0.3 3.9e-10 40.4 0.3 1.1 1 0 0 1 1 1 1 Dishevelled specific domain DIX PF00778.17 KFP22552.1 - 1.1e-06 28.4 0.1 1.4e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 DIX domain Fanconi_A PF03511.14 KFP22552.1 - 0.07 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein V-set PF07686.17 KFP22553.1 - 3.6e-27 94.7 0.1 1.8e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 KFP22553.1 - 1.1e-08 35.1 1.4 0.00087 19.4 0.2 3.2 2 2 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KFP22553.1 - 1.6e-07 31.3 0.0 0.024 14.7 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP22553.1 - 1.9e-07 31.6 1.5 0.0053 17.3 0.5 3.6 2 2 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP22553.1 - 0.0008 19.7 0.2 0.2 12.0 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KFP22553.1 - 0.0049 16.9 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain Stevor PF17410.2 KFP22553.1 - 0.0056 16.3 0.2 0.0094 15.5 0.2 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame Ig_6 PF18452.1 KFP22553.1 - 0.013 15.0 0.0 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain FixQ PF05545.11 KFP22553.1 - 0.035 14.1 0.8 0.072 13.1 0.8 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ V-set_CD47 PF08204.11 KFP22553.1 - 0.041 13.9 0.1 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.8 KFP22553.1 - 0.062 13.5 2.1 5.7 7.2 0.2 3.3 4 1 0 4 4 3 0 Natural killer cell receptor 2B4 EphA2_TM PF14575.6 KFP22553.1 - 0.12 13.3 0.0 0.38 11.7 0.0 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 KFP22553.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF347 PF03988.12 KFP22553.1 - 0.15 12.3 0.8 0.25 11.5 0.8 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF1713 PF08213.11 KFP22554.1 - 1.1e-10 41.2 20.2 1.1e-10 41.2 20.2 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Cyclin_N PF00134.23 KFP22555.1 - 3.9e-14 52.5 1.1 2.5e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP22555.1 - 5.2e-06 26.5 0.1 5.2e-06 26.5 0.1 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.19 KFP22555.1 - 0.00032 20.7 0.5 0.28 11.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KFP22555.1 - 0.0026 18.1 0.0 0.011 16.1 0.0 1.9 2 1 0 2 2 2 1 Cyclin C-terminal domain DUF936 PF06075.12 KFP22555.1 - 2.1 7.2 27.2 2.7 6.8 27.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Ribosomal_L20 PF00453.18 KFP22556.1 - 1.6e-30 105.3 1.8 2.1e-30 105.0 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 FtsX PF02687.21 KFP22557.1 - 0.075 13.5 8.7 0.11 13.0 8.7 1.3 1 0 0 1 1 1 0 FtsX-like permease family DUF2852 PF11014.8 KFP22557.1 - 0.59 10.3 2.0 0.59 10.3 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) VWA PF00092.28 KFP22558.1 - 7.5e-35 120.7 0.0 1.2e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.21 KFP22558.1 - 7.3e-23 80.7 1.2 8.5e-11 42.1 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain VWA_2 PF13519.6 KFP22558.1 - 9.4e-15 55.2 0.0 2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Pur_ac_phosph_N PF16656.5 KFP22558.1 - 6.5e-07 29.8 1.1 0.032 14.8 0.1 3.0 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KFP22558.1 - 1.1e-05 25.6 0.0 0.0088 16.3 0.0 2.3 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KFP22558.1 - 0.0022 18.3 0.0 0.43 11.0 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) DJ-1_PfpI PF01965.24 KFP22558.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family DUF1410 PF07198.11 KFP22558.1 - 0.021 15.3 0.1 7.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) Big_5 PF13205.6 KFP22558.1 - 0.032 14.9 0.9 2.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain VWA_CoxE PF05762.14 KFP22558.1 - 0.061 12.7 0.2 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DUF3523 PF12037.8 KFP22559.1 - 5.5e-89 298.1 30.5 5.5e-89 298.1 30.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.29 KFP22559.1 - 1.5e-20 73.9 0.1 4.8e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFP22559.1 - 0.00018 21.7 0.0 0.00018 21.7 0.0 2.7 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KFP22559.1 - 0.00037 19.9 0.1 0.0045 16.4 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KFP22559.1 - 0.00065 19.5 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFP22559.1 - 0.00088 19.0 0.1 0.0034 17.1 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_24 PF13479.6 KFP22559.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFP22559.1 - 0.0037 17.2 4.2 0.046 13.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 KFP22559.1 - 0.0041 16.5 0.0 0.0041 16.5 0.0 2.1 2 1 0 2 2 1 1 KaiC AAA_16 PF13191.6 KFP22559.1 - 0.0054 17.1 0.0 0.0054 17.1 0.0 3.5 2 2 0 2 2 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 KFP22559.1 - 0.012 15.7 0.3 0.035 14.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 KFP22559.1 - 0.017 15.4 8.3 0.35 11.1 0.0 3.5 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KFP22559.1 - 0.031 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KFP22559.1 - 0.044 13.8 0.0 0.19 11.7 0.0 2.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zot PF05707.12 KFP22559.1 - 0.049 13.3 0.1 0.049 13.3 0.1 3.1 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) NACHT PF05729.12 KFP22559.1 - 0.05 13.5 0.2 0.42 10.5 0.0 2.5 3 0 0 3 3 2 0 NACHT domain AAA_7 PF12775.7 KFP22559.1 - 0.099 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFP22559.1 - 0.14 12.7 2.6 0.23 12.0 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KFP22559.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.4 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KFP22559.1 - 0.7 9.6 0.0 0.7 9.6 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KFP22559.1 - 2.8 7.5 6.2 0.26 10.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain TFIIA PF03153.13 KFP22559.1 - 4.2 7.3 19.5 7.4 6.4 19.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BORG_CEP PF14957.6 KFP22559.1 - 6.7 7.9 7.0 19 6.5 7.0 1.8 1 0 0 1 1 1 0 Cdc42 effector TMEM240 PF15207.6 KFP22560.1 - 1.2e-75 253.0 1.8 1.5e-75 252.8 1.8 1.0 1 0 0 1 1 1 1 TMEM240 family Ssu72 PF04722.13 KFP22561.1 - 1.6e-51 174.6 0.7 1.7e-51 174.5 0.7 1.0 1 0 0 1 1 1 1 Ssu72-like protein 5_nucleotid PF05761.14 KFP22561.1 - 0.051 12.5 0.1 0.73 8.7 0.0 1.9 1 1 1 2 2 2 0 5' nucleotidase family 7tm_1 PF00001.21 KFP22562.1 - 8.4e-22 77.7 3.1 1e-21 77.4 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP22562.1 - 1.8e-19 70.5 3.6 2.1e-19 70.3 3.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP22562.1 - 0.0026 17.2 2.3 0.0034 16.8 2.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CholecysA-Rec_N PF09193.10 KFP22562.1 - 0.075 13.0 0.1 0.21 11.6 0.1 1.8 1 1 0 1 1 1 0 Cholecystokinin A receptor, N-terminal 7tm_4 PF13853.6 KFP22563.1 - 3.2e-07 30.4 0.4 3.5e-07 30.2 0.4 1.0 1 0 0 1 1 1 1 Olfactory receptor LSM PF01423.22 KFP22564.1 - 1.9e-16 59.5 0.5 2.5e-16 59.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain CFTR_R PF14396.6 KFP22565.1 - 3.1e-105 350.4 2.8 3.1e-105 350.4 2.8 1.9 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_membrane PF00664.23 KFP22565.1 - 2.6e-94 315.9 37.0 1.1e-50 172.9 14.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFP22565.1 - 1.3e-55 187.6 0.0 1.1e-30 106.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFP22565.1 - 8.7e-07 29.0 0.3 0.18 11.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFP22565.1 - 1.7e-06 27.6 0.0 0.02 14.3 0.0 3.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KFP22565.1 - 3e-06 26.5 0.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KFP22565.1 - 1.9e-05 24.6 0.5 0.024 14.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFP22565.1 - 2.6e-05 23.9 1.1 0.009 15.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFP22565.1 - 0.00025 21.6 6.2 0.53 10.8 0.1 3.7 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KFP22565.1 - 0.00044 20.4 1.1 0.31 11.1 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 KFP22565.1 - 0.00045 20.6 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NTPase_1 PF03266.15 KFP22565.1 - 0.0014 18.6 0.4 0.2 11.5 0.0 3.1 3 0 0 3 3 3 1 NTPase NACHT PF05729.12 KFP22565.1 - 0.0026 17.7 0.5 2.2 8.2 0.1 2.8 2 0 0 2 2 2 2 NACHT domain Intein_splicing PF14890.6 KFP22565.1 - 0.0026 17.7 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 Intein splicing domain MeaB PF03308.16 KFP22565.1 - 0.0074 15.3 0.4 0.14 11.1 0.1 2.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KFP22565.1 - 0.0091 16.1 0.1 1.1 9.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP22565.1 - 0.011 16.0 0.5 8.9 6.6 0.1 3.1 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KFP22565.1 - 0.016 14.4 0.5 0.78 8.9 0.1 2.8 3 0 0 3 3 2 0 NB-ARC domain AAA_30 PF13604.6 KFP22565.1 - 0.019 14.7 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFP22565.1 - 0.021 14.1 0.4 0.73 9.1 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KFP22565.1 - 0.04 13.4 0.1 7.3 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KFP22565.1 - 0.057 13.4 0.3 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KFP22565.1 - 0.13 11.9 1.4 6 6.4 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KFP22565.1 - 0.14 12.6 0.0 24 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.9 KFP22565.1 - 0.15 11.0 0.4 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 KFP22565.1 - 0.16 12.3 0.0 20 5.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KFP22565.1 - 0.25 11.2 1.4 34 4.3 0.1 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_2 PF12796.7 KFP22566.1 - 1.2e-27 96.3 3.1 1.1e-15 57.9 0.2 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFP22566.1 - 2.4e-26 91.0 0.2 2.2e-06 27.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFP22566.1 - 3.9e-22 78.0 2.4 2.2e-11 43.8 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP22566.1 - 5.3e-20 69.4 0.8 7.9e-05 22.8 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFP22566.1 - 7.7e-17 61.4 1.4 3.6e-06 27.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.30 KFP22566.1 - 2e-08 34.5 0.2 4.1e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFP22566.1 - 3.5e-08 33.4 0.2 8.9e-08 32.1 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) wnt PF00110.19 KFP22567.1 - 2.6e-103 345.8 22.8 3.2e-103 345.6 22.8 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.12 KFP22568.1 - 3.4e-277 920.2 0.3 3.9e-277 920.0 0.3 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KFP22568.1 - 0.00039 20.9 0.0 0.0021 18.6 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Clathrin PF00637.20 KFP22568.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_19 PF14559.6 KFP22568.1 - 0.11 13.1 4.7 0.29 11.7 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22568.1 - 0.12 12.5 5.5 3.3 8.0 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22568.1 - 0.13 12.1 2.8 23 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat F-actin_cap_A PF01267.17 KFP22570.1 - 5.2e-107 357.2 2.4 5.9e-107 357.0 2.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF5121 PF17165.4 KFP22570.1 - 0.053 13.9 0.3 0.15 12.5 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5121) CCP_MauG PF03150.14 KFP22570.1 - 0.068 13.8 0.9 0.26 11.9 0.5 2.1 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Pkinase_Tyr PF07714.17 KFP22571.1 - 4.8e-94 314.5 0.0 6.9e-94 313.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sema PF01403.19 KFP22571.1 - 2.3e-52 178.3 3.3 3.5e-52 177.7 3.3 1.3 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.25 KFP22571.1 - 1.5e-39 136.0 0.0 3e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 KFP22571.1 - 3e-35 120.1 10.2 1.1e-14 54.3 0.1 5.0 4 0 0 4 4 4 4 IPT/TIG domain PSI PF01437.25 KFP22571.1 - 3.3e-05 24.4 13.4 3.3e-05 24.4 13.4 2.4 2 0 0 2 2 2 1 Plexin repeat Kinase-like PF14531.6 KFP22571.1 - 9.4e-05 21.9 0.0 0.00029 20.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFP22571.1 - 0.0054 15.6 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Syndecan PF01034.20 KFP22571.1 - 0.17 11.8 0.1 0.45 10.5 0.1 1.7 1 0 0 1 1 1 0 Syndecan domain Caveolin PF01146.17 KFP22575.1 - 1.5e-51 173.9 5.2 1.6e-51 173.7 5.2 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.17 KFP22576.1 - 2.8e-47 160.0 5.5 3e-47 159.9 5.5 1.0 1 0 0 1 1 1 1 Caveolin PET PF06297.14 KFP22579.1 - 2.2e-41 140.0 3.2 3.7e-41 139.3 3.2 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.22 KFP22579.1 - 1.4e-27 95.6 60.4 1.5e-13 50.7 10.3 4.7 4 2 0 4 4 4 3 LIM domain SHIRT PF18655.1 KFP22579.1 - 0.036 14.6 1.0 0.73 10.5 0.1 2.5 2 0 0 2 2 2 0 SHIRT domain Ig_Tie2_1 PF10430.9 KFP22579.1 - 0.045 14.2 0.6 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 DUF3371 PF11851.8 KFP22582.1 - 6.2e-34 117.9 5.6 6.2e-34 117.9 5.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3371) HLH PF00010.26 KFP22582.1 - 1.4e-15 57.0 0.3 3.1e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MITF_TFEB_C_3_N PF15951.5 KFP22582.1 - 5e-14 53.2 1.2 5e-14 53.2 1.2 2.4 2 0 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus MDFI PF15316.6 KFP22584.1 - 1.9e-73 246.1 35.9 2.5e-73 245.8 35.9 1.1 1 0 0 1 1 1 1 MyoD family inhibitor FOXP-CC PF16159.5 KFP22588.1 - 1.5e-32 112.0 3.5 1.5e-32 112.0 3.5 3.6 2 1 1 3 3 1 1 FOXP coiled-coil domain Forkhead PF00250.18 KFP22588.1 - 3.6e-28 97.7 0.2 1.1e-27 96.0 0.2 1.9 1 0 0 1 1 1 1 Forkhead domain TT_ORF1 PF02956.14 KFP22588.1 - 0.011 14.4 9.0 0.015 14.0 9.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 hDGE_amylase PF14701.6 KFP22588.1 - 0.11 11.6 11.6 0.22 10.5 11.6 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Plasmodium_Vir PF05795.11 KFP22588.1 - 0.24 10.8 9.0 0.36 10.2 7.2 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SpoIIP PF07454.11 KFP22588.1 - 0.31 10.5 11.7 0.55 9.6 11.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PP_kinase_N PF13089.6 KFP22588.1 - 0.67 10.3 12.2 1.8 9.0 11.4 2.2 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain DUF2347 PF09804.9 KFP22588.1 - 0.73 9.4 12.0 1.4 8.4 12.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) V_ATPase_I PF01496.19 KFP22588.1 - 0.77 7.6 15.6 1.1 7.0 15.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF853 PF05872.12 KFP22588.1 - 0.98 7.9 14.8 1.5 7.3 14.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cellulose_synt PF03552.14 KFP22588.1 - 1.5 7.2 2.7 2.2 6.7 2.7 1.1 1 0 0 1 1 1 0 Cellulose synthase BRF1 PF07741.13 KFP22588.1 - 1.7 9.1 12.7 5.5 7.4 12.7 1.9 1 0 0 1 1 1 0 Brf1-like TBP-binding domain RNA_pol_Rbc25 PF08292.12 KFP22588.1 - 1.9 8.7 10.4 4.9 7.4 10.4 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 ALMT PF11744.8 KFP22588.1 - 2.2 7.0 18.7 0.28 9.9 14.5 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Folate_carrier PF01770.18 KFP22588.1 - 2.3 6.9 8.6 3.6 6.2 8.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier PIN_12 PF16289.5 KFP22588.1 - 3.5 8.1 7.0 7.6 7.0 7.0 1.5 1 0 0 1 1 1 0 PIN domain eIF-3_zeta PF05091.12 KFP22588.1 - 4.9 6.0 19.7 7.5 5.4 19.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.10 KFP22588.1 - 5.5 7.8 8.1 22 5.8 8.1 2.0 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Peptidase_S49_N PF08496.10 KFP22588.1 - 7.7 6.6 24.6 2.8 8.0 21.6 1.8 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Dis3l2_C_term PF17877.1 KFP22588.1 - 7.9 6.9 9.0 24 5.3 9.0 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal CemA PF03040.14 KFP22588.1 - 9.2 6.1 18.0 18 5.2 18.0 1.4 1 0 0 1 1 1 0 CemA family TSC22 PF01166.18 KFP22590.1 - 1.4e-28 98.9 4.3 1.5e-28 98.9 4.3 1.0 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 KFP22590.1 - 0.00011 22.8 1.6 0.00011 22.8 1.6 1.1 1 0 0 1 1 1 1 Initiation control protein YabA DivIC PF04977.15 KFP22590.1 - 0.00036 20.2 2.2 0.00041 20.1 2.2 1.1 1 0 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KFP22590.1 - 0.0012 19.3 4.3 0.0013 19.1 4.3 1.1 1 0 0 1 1 1 1 Cell division protein ZapB Lebercilin PF15619.6 KFP22590.1 - 0.0053 16.4 2.7 0.0053 16.4 2.7 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 KFP22590.1 - 0.02 15.0 1.9 0.023 14.8 1.9 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KFP22590.1 - 0.025 14.7 5.2 0.037 14.1 5.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.6 KFP22590.1 - 0.031 14.4 1.5 0.042 14.0 1.5 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain Shugoshin_N PF07558.11 KFP22590.1 - 0.07 13.0 3.4 0.097 12.6 3.4 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cu-oxidase_4 PF02578.15 KFP22591.1 - 1.8e-56 191.4 0.0 2.3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase bZIP_1 PF00170.21 KFP22592.1 - 0.023 14.8 0.7 0.023 14.8 0.7 5.4 4 3 2 6 6 6 0 bZIP transcription factor ATG16 PF08614.11 KFP22592.1 - 0.19 11.9 22.8 3.3 7.9 12.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 KFP22592.1 - 0.38 9.9 27.3 4 6.6 5.8 3.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 KFP22592.1 - 8.1 6.9 25.7 1.3 9.5 16.6 2.1 1 1 0 2 2 2 0 Fez1 DUF1664 PF07889.12 KFP22592.1 - 9.4 6.3 17.4 1.5 8.8 5.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 KFP22593.1 - 4.3e-09 36.1 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP22593.1 - 0.0032 17.6 0.1 0.064 13.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif bZIP_1 PF00170.21 KFP22593.1 - 0.087 12.9 0.5 0.087 12.9 0.5 4.0 3 0 0 3 3 3 0 bZIP transcription factor Phage_holin_7_1 PF16081.5 KFP22593.1 - 0.54 10.4 1.4 0.92 9.7 0.0 1.9 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family SesA PF17107.5 KFP22593.1 - 2.7 8.2 11.3 9.2 6.5 3.1 2.8 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Cob_adeno_trans PF01923.18 KFP22593.1 - 3.3 7.8 7.5 11 6.2 2.1 2.5 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF1759 PF03564.15 KFP22593.1 - 4.1 7.3 10.1 2.4 8.1 4.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) RAB3GAP2_C PF14656.6 KFP22594.1 - 5.8e-232 771.2 19.5 8.4e-232 770.7 19.5 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 KFP22594.1 - 1.5e-161 538.3 0.0 3.2e-161 537.2 0.0 1.6 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SRP54_N PF02881.19 KFP22594.1 - 8.2 6.7 8.0 6.7 7.0 0.0 4.3 5 1 1 6 6 6 0 SRP54-type protein, helical bundle domain tRNA-synt_1 PF00133.22 KFP22595.1 - 9.8e-166 552.5 0.1 1.5e-165 551.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFP22595.1 - 5.3e-26 91.4 0.0 1.4e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFP22595.1 - 7.3e-25 87.5 0.6 6.1e-16 58.2 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFP22595.1 - 4e-05 23.2 0.0 6.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFP22595.1 - 0.0001 21.8 0.0 0.041 13.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Inositol_P PF00459.25 KFP22596.1 - 1e-58 199.0 0.6 1.4e-58 198.6 0.6 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_1c PF00749.21 KFP22597.1 - 8.4e-123 409.2 0.5 1.6e-122 408.4 0.5 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain WHEP-TRS PF00458.20 KFP22597.1 - 9e-95 310.7 37.8 3.7e-24 84.6 1.4 5.0 4 0 0 4 4 4 4 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 KFP22597.1 - 7.7e-37 126.8 0.0 2.7e-36 125.1 0.0 2.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 KFP22597.1 - 4.8e-21 74.7 0.4 1.7e-20 73.0 0.4 2.1 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KFP22597.1 - 6.3e-18 64.7 0.4 1.1e-16 60.7 0.0 3.2 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFP22597.1 - 1.4e-17 64.3 0.1 2.8e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) GST_C_3 PF14497.6 KFP22597.1 - 0.00024 21.2 1.9 0.0016 18.6 0.0 3.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFP22597.1 - 0.001 19.2 0.0 0.0087 16.3 0.0 2.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KFP22597.1 - 0.044 13.1 0.7 0.096 12.0 0.7 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ELFV_dehydrog PF00208.21 KFP22597.1 - 0.059 13.1 0.2 2.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GST_C_2 PF13410.6 KFP22597.1 - 0.15 12.1 0.0 0.52 10.4 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 3HCDH PF00725.22 KFP22597.1 - 0.16 12.6 3.3 1e+02 3.6 0.0 4.4 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain RuvC PF02075.17 KFP22597.1 - 1.1 9.2 6.8 9.8 6.0 0.1 3.6 4 0 0 4 4 4 0 Crossover junction endodeoxyribonuclease RuvC Cation_efflux PF01545.21 KFP22598.1 - 1.2e-37 129.6 10.2 3.2e-37 128.2 10.2 1.6 1 1 0 1 1 1 1 Cation efflux family DUF2721 PF11026.8 KFP22598.1 - 4.1 7.3 8.2 2.7 7.9 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) RVT_1 PF00078.27 KFP22599.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_2 PF02230.16 KFP22601.1 - 7.1e-36 124.1 0.0 8.5e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP22601.1 - 4e-07 30.1 0.0 0.00025 21.0 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP22601.1 - 1e-06 28.2 0.1 0.0013 18.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFP22601.1 - 3.4e-06 26.7 1.1 0.00021 20.8 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KFP22601.1 - 5.1e-05 22.9 0.0 6.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KFP22601.1 - 0.00013 21.7 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 KFP22601.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP22601.1 - 0.0065 16.2 0.2 0.015 15.0 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFP22601.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KFP22601.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 KFP22601.1 - 0.13 12.9 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cbl_N3 PF02762.14 KFP22601.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain UPF0227 PF05728.12 KFP22601.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase_phd PF10503.9 KFP22601.1 - 0.18 11.2 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase TGFb_propeptide PF00688.18 KFP22603.1 - 2.3e-36 125.8 0.0 3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.20 KFP22603.1 - 5.1e-24 85.2 1.3 1.4e-23 83.8 1.3 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain SPEG_u2 PF16650.5 KFP22603.1 - 0.76 10.0 4.4 0.16 12.1 0.5 1.8 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein Rrp15p PF07890.12 KFP22604.1 - 1.1e-33 116.4 14.5 1.1e-33 116.4 14.5 1.6 2 0 0 2 2 2 1 Rrp15p DUF3499 PF12005.8 KFP22604.1 - 6.4 7.4 10.5 1.8 9.2 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) IQ PF00612.27 KFP22606.1 - 8e-12 43.9 24.9 0.00022 20.7 2.0 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif Pfg27 PF09216.10 KFP22606.1 - 0.056 13.3 9.2 0.12 12.3 9.2 1.4 1 0 0 1 1 1 0 Pfg27 G-patch PF01585.23 KFP22607.1 - 8.7e-17 60.8 1.5 1.8e-16 59.8 1.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFP22607.1 - 8.9e-09 35.3 0.4 8.9e-09 35.3 0.4 2.5 3 0 0 3 3 3 1 G-patch domain Hormone_recep PF00104.30 KFP22608.1 - 1.9e-32 112.6 0.4 2.9e-32 112.0 0.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP22608.1 - 6.6e-31 106.6 12.3 1.3e-30 105.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAT PF03127.14 KFP22608.1 - 0.19 12.0 2.1 0.6 10.5 0.3 2.4 2 0 0 2 2 2 0 GAT domain SLY PF12485.8 KFP22609.1 - 1.6e-53 181.6 7.6 1.6e-53 181.6 7.6 2.2 3 0 0 3 3 3 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.17 KFP22609.1 - 2.9e-08 33.7 0.2 6.2e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFP22609.1 - 8.8e-08 32.5 0.0 2.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KFP22609.1 - 6.3e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP22609.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SAM_KSR1 PF13543.6 KFP22609.1 - 0.027 14.6 1.2 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 TAXi_N PF14543.6 KFP22610.1 - 0.021 15.0 1.2 0.026 14.8 1.2 1.1 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Lipase PF00151.19 KFP22611.1 - 6.9e-84 282.0 0.0 9e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Lipase Ig_3 PF13927.6 KFP22614.1 - 2.5e-18 66.4 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP22614.1 - 3.9e-16 58.9 0.0 5.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP22614.1 - 1.1e-12 48.1 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP22614.1 - 2.4e-08 34.0 0.0 5.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP22614.1 - 6.6e-05 23.0 0.0 0.0023 18.1 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP22614.1 - 0.00024 21.1 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KFP22614.1 - 0.05 13.7 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 KFP22614.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 KFP22615.1 - 3.7e-73 241.7 0.0 4.1e-22 78.0 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP22615.1 - 8.3e-64 212.2 0.4 6.6e-16 58.7 0.1 5.6 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 KFP22615.1 - 1.9e-42 143.3 0.0 2.8e-09 37.0 0.0 4.8 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP22615.1 - 9.4e-42 141.2 0.0 5.7e-10 39.4 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KFP22615.1 - 2.6e-37 127.0 10.7 7.9e-15 55.0 0.9 4.2 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KFP22615.1 - 3.3e-29 101.2 5.7 2.1e-08 34.3 0.0 7.2 5 3 0 5 5 5 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KFP22615.1 - 3.2e-14 52.2 0.0 0.00047 19.6 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 KFP22615.1 - 5.2e-08 33.2 0.0 0.28 11.6 0.0 4.5 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KFP22615.1 - 5.4e-07 29.8 0.1 0.99 9.7 0.0 4.6 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFP22615.1 - 5.7e-05 23.1 0.0 2.8 8.0 0.0 4.3 4 0 0 4 4 4 1 C17orf99 Ig domain Receptor_2B4 PF11465.8 KFP22615.1 - 0.0021 18.2 0.2 4.5 7.5 0.0 4.4 3 2 1 4 4 4 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 KFP22615.1 - 0.022 14.8 0.3 62 3.7 0.0 4.4 5 0 0 5 5 4 0 Izumo-like Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KFP22615.1 - 0.039 13.7 0.3 0.48 10.2 0.0 2.9 5 0 0 5 5 4 0 Adenovirus E3 region protein CR1 fn3_4 PF16794.5 KFP22615.1 - 0.1 12.6 0.1 9.4 6.2 0.0 3.1 3 0 0 3 3 3 0 Fibronectin-III type domain I-set PF07679.16 KFP22616.1 - 1.2e-72 240.0 0.0 6.4e-23 80.6 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP22616.1 - 1.3e-62 208.3 3.6 5.9e-17 62.0 0.1 5.8 6 0 0 6 6 5 4 Immunoglobulin domain ig PF00047.25 KFP22616.1 - 3.8e-38 129.5 0.0 6.5e-09 35.9 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KFP22616.1 - 6.1e-35 119.4 0.0 1.1e-08 35.3 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 KFP22616.1 - 3.6e-33 113.8 9.3 2.3e-12 47.1 0.3 4.2 3 0 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KFP22616.1 - 2.6e-22 79.0 7.8 3.4e-09 36.8 0.0 7.8 6 2 1 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP22616.1 - 9.7e-10 38.4 4.0 0.15 12.2 0.0 5.8 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP22616.1 - 1.8e-09 37.0 0.0 1 9.0 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 KFP22616.1 - 2.7e-09 37.3 0.0 0.35 11.3 0.0 4.7 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KFP22616.1 - 0.00029 21.3 2.8 0.28 11.8 0.1 3.9 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_C17orf99 PF17736.1 KFP22616.1 - 0.00063 19.7 0.0 4.2 7.5 0.0 4.5 4 1 1 5 5 5 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP22616.1 - 0.037 14.1 0.2 36 4.5 0.0 4.0 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Big_4 PF07532.11 KFP22616.1 - 0.04 13.7 2.6 0.22 11.3 0.6 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Receptor_2B4 PF11465.8 KFP22616.1 - 0.064 13.5 0.0 36 4.6 0.0 4.0 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 fn3_4 PF16794.5 KFP22616.1 - 0.13 12.2 0.0 18 5.4 0.0 2.8 2 0 0 2 2 2 0 Fibronectin-III type domain TFIIE-A_C PF11521.8 KFP22616.1 - 0.3 11.4 2.1 9.5 6.6 0.9 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ig_3 PF13927.6 KFP22619.1 - 1.1e-17 64.4 0.0 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KFP22619.1 - 9.8e-16 57.6 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP22619.1 - 2.2e-12 47.2 0.0 2.6e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KFP22619.1 - 4.3e-08 33.2 0.0 9.4e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KFP22619.1 - 1.4e-05 25.3 0.0 0.00063 19.9 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP22619.1 - 0.00032 20.7 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 KFP22619.1 - 0.017 15.2 0.0 0.21 11.6 0.0 2.0 1 1 0 1 1 1 0 C17orf99 Ig domain Ig_6 PF18452.1 KFP22619.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain XRN_M PF17846.1 KFP22621.1 - 3.4e-167 556.9 0.0 4.5e-167 556.5 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFP22621.1 - 3.5e-94 314.8 0.0 7e-94 313.8 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Rap_GAP PF02145.15 KFP22622.1 - 7.8e-46 156.0 0.0 1.8e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP IBV_3A PF03617.13 KFP22622.1 - 2.7 8.0 5.0 0.78 9.8 0.2 2.5 2 0 0 2 2 2 0 IBV 3A protein OAR PF03826.17 KFP22623.1 - 9.1e-08 31.7 1.3 1.9e-07 30.6 1.3 1.6 1 0 0 1 1 1 1 OAR domain Pterin_4a PF01329.19 KFP22624.1 - 4e-32 110.3 0.1 4.5e-32 110.1 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 KFP22624.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 1 1 2 2 2 0 Translation-initiation factor 2 Thioredoxin PF00085.20 KFP22625.1 - 4.1e-10 39.6 0.0 5.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFP22625.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF5568 PF17724.1 KFP22626.1 - 3.9e-97 323.5 10.9 4.4e-97 323.3 10.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5568) DEAD PF00270.29 KFP22627.1 - 4.4e-51 173.1 0.2 2e-50 171.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFP22627.1 - 1.7e-27 96.0 0.0 6e-26 91.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CdAMP_rec PF06153.11 KFP22627.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Cyclic-di-AMP receptor CAML PF14963.6 KFP22628.1 - 2.4e-115 385.3 0.0 2.7e-115 385.2 0.0 1.0 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand ERGIC_N PF13850.6 KFP22628.1 - 0.27 11.6 2.7 1.7 9.0 0.2 2.9 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sec23_trunk PF04811.15 KFP22629.1 - 4.4e-86 288.4 0.1 8.3e-86 287.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFP22629.1 - 4.4e-25 87.5 0.6 1e-24 86.3 0.6 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFP22629.1 - 1.4e-20 73.8 0.0 3.5e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFP22629.1 - 9.1e-15 54.4 4.5 2.2e-14 53.2 4.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFP22629.1 - 6.7e-10 38.7 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.10 KFP22629.1 - 0.071 13.4 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein Arf PF00025.21 KFP22630.1 - 2.2e-61 206.3 0.0 2.5e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KFP22630.1 - 5.4e-10 39.0 0.0 1.2e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFP22630.1 - 3.8e-09 36.2 0.0 4.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFP22630.1 - 2.3e-07 31.0 0.0 5.1e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP22630.1 - 1.5e-06 27.9 0.0 1.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KFP22630.1 - 3.2e-06 27.2 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFP22630.1 - 0.00072 19.1 0.0 0.0084 15.7 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Metalloenzyme PF01676.18 KFP22630.1 - 0.004 16.6 0.0 0.056 12.8 0.0 2.0 1 1 1 2 2 2 1 Metalloenzyme superfamily Gtr1_RagA PF04670.12 KFP22630.1 - 0.0086 15.5 0.0 0.0097 15.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-HC5HC2H_2 PF13832.6 KFP22631.1 - 9.1e-30 103.1 8.0 9.1e-30 103.1 8.0 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFP22631.1 - 3.5e-23 81.6 8.1 3.5e-23 81.6 8.1 3.7 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFP22631.1 - 2.5e-12 46.1 7.0 2.5e-12 46.1 7.0 4.0 5 0 0 5 5 5 1 PHD-finger PHD PF00628.29 KFP22631.1 - 2.6e-10 40.0 7.8 2.6e-10 40.0 7.8 3.3 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KFP22631.1 - 1.8e-06 28.4 0.1 1.8e-06 28.4 0.1 3.1 4 1 0 4 4 4 1 Enhancer of polycomb-like C1_1 PF00130.22 KFP22631.1 - 0.0048 16.8 4.0 0.0048 16.8 4.0 3.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FerA PF08165.11 KFP22631.1 - 0.14 12.1 1.6 0.28 11.2 0.2 2.1 2 0 0 2 2 2 0 FerA (NUC095) domain C1_2 PF03107.16 KFP22631.1 - 0.59 10.5 24.6 0.081 13.3 5.0 3.4 3 0 0 3 3 3 0 C1 domain UQ_con PF00179.26 KFP22632.1 - 2.8e-46 156.6 0.1 7.2e-39 132.6 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 KFP22632.1 - 0.00097 19.4 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Citrate_bind PF16114.5 KFP22632.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding UEV PF05743.13 KFP22632.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Metallophos PF00149.28 KFP22633.1 - 1.2e-34 120.7 0.5 1.8e-34 120.1 0.4 1.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFP22633.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KFP22633.1 - 0.083 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Skp1_POZ PF03931.15 KFP22634.1 - 2.2e-30 104.6 0.7 4.9e-30 103.5 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 KFP22634.1 - 2.4e-30 104.4 1.6 4.7e-30 103.5 1.6 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Porin_3 PF01459.22 KFP22635.1 - 2.6e-82 276.3 3.7 2.9e-82 276.2 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin SusE PF14292.6 KFP22635.1 - 0.074 13.3 2.2 0.075 13.3 0.4 2.0 2 0 0 2 2 2 0 SusE outer membrane protein KCT2 PF17818.1 KFP22636.1 - 1.1e-91 306.0 1.8 1.6e-91 305.5 1.8 1.2 1 0 0 1 1 1 1 Keratinocyte-associated gene product TMEM40 PF15817.5 KFP22636.1 - 0.037 13.8 0.1 0.068 12.9 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 40 family GAT PF03127.14 KFP22636.1 - 0.32 11.3 0.2 0.32 11.3 0.2 2.8 2 1 1 3 3 3 0 GAT domain Ig_3 PF13927.6 KFP22637.1 - 1.1e-28 99.7 0.1 4.3e-17 62.5 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP22637.1 - 5e-26 90.6 0.0 1.4e-15 57.2 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP22637.1 - 2.7e-16 59.7 0.0 1.7e-08 34.6 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP22637.1 - 2.2e-14 53.4 0.1 1.8e-06 28.0 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Kazal_2 PF07648.15 KFP22637.1 - 8.5e-09 35.4 5.5 2.7e-08 33.8 5.5 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.32 KFP22637.1 - 9.4e-09 34.2 0.1 2.6e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KFP22637.1 - 2.1e-08 33.3 0.5 0.0025 17.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFP22637.1 - 5.5e-07 29.0 1.5 0.0031 17.3 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain V-set PF07686.17 KFP22637.1 - 3e-06 27.4 2.6 0.25 11.5 0.1 4.0 3 1 0 3 3 2 2 Immunoglobulin V-set domain Kazal_1 PF00050.21 KFP22637.1 - 1.2e-05 25.2 7.5 3.3e-05 23.8 7.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.6 KFP22637.1 - 1.9e-05 25.0 4.3 4.4e-05 23.9 4.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ig_6 PF18452.1 KFP22637.1 - 4.9e-05 22.8 0.8 0.017 14.7 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin domain SPARC_Ca_bdg PF10591.9 KFP22637.1 - 0.00042 20.6 0.3 0.00085 19.6 0.3 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KFP22637.1 - 0.001 18.8 0.5 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair C2-set_2 PF08205.12 KFP22637.1 - 0.0016 18.5 0.0 0.55 10.3 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP22637.1 - 0.0024 18.2 0.1 0.28 11.6 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Dockerin_1 PF00404.18 KFP22637.1 - 0.066 13.4 0.1 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain RasGEF_N PF00618.20 KFP22639.1 - 9.4e-15 54.7 0.4 3.8e-13 49.6 0.4 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KFP22639.1 - 2.2e-12 47.4 0.0 7.5e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KFP22639.1 - 2.7e-12 46.9 0.0 5.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP22639.1 - 1.2e-11 44.3 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain cNMP_binding PF00027.29 KFP22639.1 - 2e-07 31.0 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PDZ_2 PF13180.6 KFP22639.1 - 4.5e-05 23.7 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF1908 PF08926.11 KFP22641.1 - 2.5e-135 450.1 1.3 2.5e-135 450.1 1.3 3.4 5 0 0 5 5 4 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KFP22641.1 - 1.7e-61 207.9 0.0 3.5e-61 206.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22641.1 - 1.3e-26 93.4 0.0 3.1e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 KFP22641.1 - 4.3e-11 42.5 0.4 1.1e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KFP22641.1 - 1e-09 38.6 0.0 2.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP22641.1 - 2.4e-06 27.8 0.0 6.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KFP22641.1 - 6.7e-06 26.2 0.0 0.031 14.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP22641.1 - 0.00055 19.3 0.0 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KFP22641.1 - 0.016 14.8 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Tricorn_PDZ PF14685.6 KFP22641.1 - 0.019 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Kdo PF06293.14 KFP22641.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACTL7A_N PF16840.5 KFP22641.1 - 0.14 12.2 0.2 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Actin-like protein 7A N-terminus DAAD PF18752.1 KFP22641.1 - 0.2 11.5 3.7 7.8 6.2 0.4 2.7 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase RRM_1 PF00076.22 KFP22644.1 - 2.1e-13 49.9 0.1 3.7e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFP22644.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 KFP22645.1 - 3.7e-37 125.9 30.7 8.3e-09 35.1 1.9 7.2 3 1 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 KFP22645.1 - 4.8e-27 93.6 40.1 0.00091 19.6 2.0 9.9 6 2 3 10 10 10 9 Leucine Rich repeats (2 copies) PDZ PF00595.24 KFP22645.1 - 1.6e-13 50.8 0.1 3.8e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 KFP22645.1 - 1.8e-06 27.9 5.4 0.0082 16.1 0.3 3.9 2 1 3 5 5 5 3 BspA type Leucine rich repeat region (6 copies) PDZ_6 PF17820.1 KFP22645.1 - 8.1e-06 25.6 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KFP22645.1 - 5.2e-05 23.5 0.0 0.00083 19.6 0.0 2.8 2 0 0 2 2 2 1 PDZ domain LRR_1 PF00560.33 KFP22645.1 - 0.023 15.2 28.0 13 6.8 0.1 11.5 11 2 0 11 11 11 0 Leucine Rich Repeat DUF240 PF03086.14 KFP22645.1 - 0.063 13.2 0.1 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF240) RsmF_methylt_CI PF17126.5 KFP22645.1 - 0.17 11.9 0.3 6.6 6.9 0.0 3.6 4 0 0 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KFP22645.1 - 1.5 9.0 23.4 13 6.1 0.1 7.7 8 0 0 8 8 8 0 Leucine Rich repeat Peptidase_M3 PF01432.20 KFP22647.1 - 2.2e-152 508.5 0.1 3.1e-152 508.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Transthyretin PF00576.21 KFP22647.1 - 0.065 13.9 0.2 1.4 9.7 0.0 2.4 2 0 0 2 2 2 0 HIUase/Transthyretin family TPR_1 PF00515.28 KFP22648.1 - 1e-28 97.9 10.3 7.3e-10 38.2 1.6 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22648.1 - 7.5e-23 78.8 6.5 2.6e-06 27.1 0.7 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22648.1 - 2e-21 75.4 11.6 3.1e-08 33.2 1.0 4.1 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 KFP22648.1 - 3.5e-19 67.4 7.4 4.8e-06 26.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 KFP22648.1 - 6.1e-18 64.4 0.7 6.9e-16 57.8 0.0 3.0 3 0 0 3 3 3 1 Homodimerisation domain of SGTA TPR_17 PF13431.6 KFP22648.1 - 5.6e-15 54.6 6.0 9e-08 32.0 1.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22648.1 - 1.6e-14 52.7 0.4 0.00016 21.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22648.1 - 6e-10 39.1 0.0 0.063 14.1 0.0 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22648.1 - 2.3e-09 37.3 0.1 2.3e-06 27.7 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22648.1 - 6.2e-09 36.0 3.0 0.00029 21.0 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22648.1 - 7.7e-09 35.9 1.8 5.1e-05 23.7 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22648.1 - 8.4e-09 35.9 0.1 7.2e-05 23.4 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP22648.1 - 8.7e-06 25.4 5.4 0.049 13.5 0.5 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KFP22648.1 - 9.4e-06 25.5 2.5 0.0043 16.8 0.3 3.4 2 1 1 3 3 2 1 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.9 KFP22648.1 - 6.1e-05 22.4 0.1 0.68 9.4 0.1 3.4 3 0 0 3 3 3 2 SHNi-TPR TPR_6 PF13174.6 KFP22648.1 - 0.00022 21.7 0.5 1.5 9.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFP22648.1 - 0.00034 20.6 8.7 0.025 14.6 0.4 3.8 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 KFP22648.1 - 0.00047 20.1 0.6 0.007 16.4 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF627) BTAD PF03704.17 KFP22648.1 - 0.0028 18.1 0.3 0.014 15.9 0.1 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain MIT PF04212.18 KFP22648.1 - 0.0038 17.3 10.6 0.51 10.4 0.1 4.2 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 KFP22648.1 - 0.011 15.0 0.2 4.3 6.5 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 KFP22648.1 - 0.019 14.7 10.7 0.26 11.0 3.2 2.7 2 0 0 2 2 2 0 XPC-binding domain GerD PF17898.1 KFP22648.1 - 0.037 14.0 0.2 0.55 10.2 0.1 2.5 2 0 0 2 2 2 0 Spore germination GerD central core domain ANAPC3 PF12895.7 KFP22648.1 - 0.051 13.8 2.9 0.16 12.2 2.9 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KFP22648.1 - 0.2 11.8 1.1 23 5.0 1.1 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) T3SSipB PF16535.5 KFP22648.1 - 0.21 12.0 2.6 0.25 11.8 0.3 2.2 2 1 1 3 3 3 0 Type III cell invasion protein SipB STI1 PF17830.1 KFP22648.1 - 1.7 8.6 8.3 0.27 11.2 2.2 2.5 2 0 0 2 2 2 0 STI1 domain DUF974 PF06159.13 KFP22649.1 - 4.6e-85 285.4 0.5 6.6e-85 284.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 KFP22649.1 - 0.0016 18.5 0.4 0.027 14.6 0.0 2.8 2 1 1 3 3 3 1 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.7 KFP22649.1 - 0.0023 17.4 0.0 3 7.2 0.0 3.2 2 1 1 3 3 3 2 TRAPP trafficking subunit Trs65 APOBEC3 PF18771.1 KFP22650.1 - 0.0065 16.6 0.0 0.018 15.2 0.0 1.9 1 1 0 1 1 1 1 APOBEC3 Arf PF00025.21 KFP22651.1 - 4.7e-71 237.8 0.5 1e-70 236.7 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KFP22651.1 - 4.5e-14 52.7 0.2 5.7e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFP22651.1 - 5.7e-12 45.5 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KFP22651.1 - 3.5e-11 42.8 0.0 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFP22651.1 - 3.1e-10 39.8 0.1 8e-08 31.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit zf-B_box PF00643.24 KFP22651.1 - 9.2e-07 28.9 5.4 9.2e-07 28.9 5.4 4.0 4 0 0 4 4 3 2 B-box zinc finger zf-RING_UBOX PF13445.6 KFP22651.1 - 1.1e-06 28.6 5.1 1.1e-06 28.6 5.1 2.9 3 0 0 3 3 3 1 RING-type zinc-finger Gtr1_RagA PF04670.12 KFP22651.1 - 1.2e-06 28.0 0.0 2.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_5 PF14634.6 KFP22651.1 - 1.7e-06 27.8 1.9 1.7e-06 27.8 1.9 4.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP22651.1 - 3.4e-05 24.1 3.0 3.4e-05 24.1 3.0 4.2 4 0 0 4 4 4 1 Ring finger domain MMR_HSR1 PF01926.23 KFP22651.1 - 0.0002 21.4 0.1 0.00078 19.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4 PF00097.25 KFP22651.1 - 0.00037 20.3 1.3 0.00037 20.3 1.3 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP22651.1 - 0.0068 16.2 3.6 0.0068 16.2 3.6 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP22651.1 - 0.007 16.2 3.2 0.007 16.2 3.2 3.3 4 0 0 4 4 3 1 Prokaryotic RING finger family 4 Thymidylate_kin PF02223.17 KFP22651.1 - 0.16 11.6 1.1 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase FemAB PF02388.16 KFP22651.1 - 0.46 9.3 1.6 0.42 9.4 0.3 1.5 2 0 0 2 2 2 0 FemAB family Pro_isomerase PF00160.21 KFP22652.1 - 3.2e-50 170.5 0.1 6.6e-50 169.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFP22652.1 - 5.7e-11 42.8 2.0 0.065 14.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP22652.1 - 0.0014 18.9 0.0 2.1 8.7 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF505 PF04458.12 KFP22652.1 - 0.023 13.1 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Ge1_WD40 PF16529.5 KFP22652.1 - 0.088 11.8 0.3 25 3.7 0.0 3.5 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-K PF11802.8 KFP22653.1 - 1.3e-102 342.9 12.2 1.5e-102 342.7 12.2 1.1 1 0 0 1 1 1 1 Centromere-associated protein K Phage_GPO PF05929.11 KFP22653.1 - 0.14 11.7 2.5 0.19 11.3 2.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2063 PF09836.9 KFP22653.1 - 0.15 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Exonuc_VII_L PF02601.15 KFP22653.1 - 0.16 11.5 4.4 0.22 11.1 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MIS13 PF08202.11 KFP22653.1 - 0.64 9.2 12.0 1.2 8.4 12.0 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Duffy_binding PF05424.11 KFP22653.1 - 0.79 9.7 6.0 1.1 9.3 6.0 1.4 1 1 0 1 1 1 0 Duffy binding domain zf-C4H2 PF10146.9 KFP22653.1 - 1.8 8.8 11.4 0.54 10.5 6.8 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Occludin_ELL PF07303.13 KFP22653.1 - 2.3 9.0 11.9 4 8.2 8.0 2.3 2 1 0 2 2 2 0 Occludin homology domain Spc24 PF08286.11 KFP22653.1 - 2.3 8.5 13.2 4.8 7.5 8.9 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LMBR1 PF04791.16 KFP22653.1 - 7.9 5.3 8.1 10 4.9 8.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CCHC_3 PF13917.6 KFP22655.1 - 3.5e-08 33.3 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KFP22655.1 - 0.036 14.1 2.7 0.049 13.7 2.7 1.2 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.6 KFP22655.1 - 0.048 13.7 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 CpXC protein UNC45-central PF11701.8 KFP22656.1 - 5.3e-32 110.9 9.3 3.2e-31 108.4 0.1 3.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central TPR_8 PF13181.6 KFP22656.1 - 3.9e-06 26.6 0.8 0.00013 21.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22656.1 - 2.2e-05 24.2 4.4 0.00015 21.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22656.1 - 5.2e-05 22.9 0.9 0.0042 16.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22656.1 - 0.00087 19.4 1.2 0.0026 17.9 1.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP22656.1 - 0.0034 17.9 0.8 0.043 14.5 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 KFP22656.1 - 0.0052 17.2 14.7 8.4 6.9 0.0 6.5 7 1 0 7 7 7 2 HEAT repeats Arm PF00514.23 KFP22656.1 - 0.0069 16.4 10.8 5.5 7.2 0.1 7.3 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat TPR_14 PF13428.6 KFP22656.1 - 0.047 14.5 0.1 0.047 14.5 0.1 3.2 3 1 0 3 3 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFP22656.1 - 0.074 12.3 0.7 0.14 11.3 0.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3587 PF12132.8 KFP22656.1 - 0.082 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) Fis1_TPR_N PF14852.6 KFP22656.1 - 0.09 12.5 0.0 34 4.2 0.0 3.3 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat V-ATPase_H_N PF03224.14 KFP22656.1 - 0.18 11.1 4.6 0.23 10.7 0.2 3.0 4 1 0 4 4 4 0 V-ATPase subunit H TPR_19 PF14559.6 KFP22656.1 - 0.36 11.4 3.8 1.5 9.4 3.8 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22656.1 - 0.87 10.3 5.4 0.31 11.7 1.2 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat RCC1 PF00415.18 KFP22657.1 - 4.2e-09 36.9 0.0 4.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat MAP65_ASE1 PF03999.12 KFP22658.1 - 1.8e-146 489.3 27.2 2.1e-146 489.1 27.2 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DinI PF06183.13 KFP22658.1 - 0.9 9.9 7.2 1.5 9.2 0.0 3.6 4 0 0 4 4 4 0 DinI-like family Sec1 PF00995.23 KFP22659.1 - 1.3e-56 193.1 0.0 2.2e-48 165.9 0.2 2.0 2 0 0 2 2 2 2 Sec1 family EF-hand_7 PF13499.6 KFP22660.1 - 5.7e-14 52.3 3.8 1e-12 48.3 0.7 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP22660.1 - 4.9e-12 44.5 4.6 4.2e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP22660.1 - 2.4e-11 42.6 1.8 3.1e-05 23.6 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFP22660.1 - 1.5e-10 40.8 2.2 0.00017 21.4 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP22660.1 - 2.8e-08 32.9 1.7 0.0033 16.8 0.3 2.3 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KFP22660.1 - 0.0014 19.0 0.3 0.015 15.6 0.3 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KFP22660.1 - 0.0016 18.6 0.1 0.003 17.7 0.1 1.5 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_4 PF12763.7 KFP22660.1 - 0.0025 17.7 1.4 0.32 11.0 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFP22660.1 - 0.022 15.1 0.6 0.79 10.1 0.1 2.8 2 1 0 2 2 2 0 EF-hand domain DUF1389 PF07146.11 KFP22660.1 - 0.041 13.1 0.1 0.048 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) S_100 PF01023.19 KFP22660.1 - 0.042 13.6 0.1 5.1 6.9 0.1 2.5 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain DUF4745 PF15923.5 KFP22660.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4745) EF-hand_7 PF13499.6 KFP22661.1 - 4.2e-13 49.5 5.7 4.1e-12 46.4 1.9 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP22661.1 - 4.1e-12 44.7 5.3 2e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFP22661.1 - 9.2e-11 40.8 3.8 3.6e-05 23.3 0.3 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFP22661.1 - 3.1e-09 36.5 4.8 0.00019 21.2 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFP22661.1 - 3.6e-08 32.5 2.1 0.0036 16.7 0.3 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KFP22661.1 - 2e-05 24.9 0.8 0.00028 21.2 0.8 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region S_100 PF01023.19 KFP22661.1 - 0.0012 18.5 0.3 5.5 6.8 0.1 3.4 3 0 0 3 3 3 1 S-100/ICaBP type calcium binding domain EF-hand_4 PF12763.7 KFP22661.1 - 0.0024 17.8 3.1 0.092 12.7 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFP22661.1 - 0.004 17.3 0.7 0.0089 16.2 0.7 1.6 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_9 PF14658.6 KFP22661.1 - 0.0062 16.8 0.8 0.11 12.8 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain NuiA PF07924.11 KFP22661.1 - 0.0093 16.4 0.1 0.012 16.0 0.1 1.2 1 0 0 1 1 1 1 Nuclease A inhibitor-like protein Gal4_dimer PF03902.13 KFP22661.1 - 0.021 15.0 2.7 0.15 12.2 0.5 2.2 1 1 1 2 2 2 0 Gal4-like dimerisation domain FDX-ACB PF03147.14 KFP22661.1 - 0.18 12.2 0.9 4.8 7.7 0.9 2.1 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain RhoGEF PF00621.20 KFP22662.1 - 8.1e-44 150.0 2.4 8.1e-44 150.0 2.4 1.9 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KFP22662.1 - 1.9e-10 40.2 1.8 3.9e-10 39.2 1.8 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP22662.1 - 1.1e-09 37.8 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFP22662.1 - 3.6e-09 36.3 0.1 7.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP22662.1 - 3.9e-07 30.5 0.4 8.4e-07 29.5 0.4 1.5 1 0 0 1 1 1 1 PH domain Kazal_1 PF00050.21 KFP22663.1 - 1.6e-16 60.0 6.1 3.3e-16 59.0 1.3 2.0 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 KFP22663.1 - 2.5e-11 43.5 4.8 3.5e-11 43.0 0.8 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain zf-RING_11 PF17123.5 KFP22663.1 - 5.8 6.8 6.8 0.26 11.1 0.8 1.9 2 1 0 2 2 2 0 RING-like zinc finger XPA_C PF05181.12 KFP22664.1 - 9.7e-30 102.3 0.7 1.1e-29 102.2 0.7 1.0 1 0 0 1 1 1 1 XPA protein C-terminus MIF4G_like_2 PF09090.11 KFP22665.1 - 5.7e-86 288.3 3.1 1.3e-85 287.1 3.1 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KFP22665.1 - 9.2e-37 126.7 0.9 5.7e-36 124.1 0.6 2.2 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KFP22665.1 - 5.7e-26 91.5 2.1 8.5e-26 90.9 0.1 2.5 3 0 0 3 3 3 1 MIF4G domain DUF4611 PF15387.6 KFP22665.1 - 0.035 14.3 1.0 0.035 14.3 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nuf2 PF03800.14 KFP22665.1 - 0.073 13.2 0.0 3.8 7.6 0.0 2.7 1 1 1 2 2 2 0 Nuf2 family Vfa1 PF08432.10 KFP22665.1 - 0.077 13.3 1.2 0.14 12.4 1.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mis12 PF05859.12 KFP22665.1 - 0.079 13.0 1.4 0.37 10.8 1.4 2.2 1 0 0 1 1 1 0 Mis12 protein DASH_Spc34 PF08657.10 KFP22665.1 - 0.42 10.4 5.7 0.78 9.5 5.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 PBP1_TM PF14812.6 KFP22665.1 - 0.93 9.9 10.9 0.11 12.9 5.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0176_N PF17773.1 KFP22666.1 - 1.9e-17 63.4 0.0 3.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 KFP22666.1 - 7.8e-16 58.2 11.5 7.8e-16 58.2 11.5 2.1 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 KFP22666.1 - 3.1e-07 30.9 0.1 8.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain NRDD PF13597.6 KFP22666.1 - 0.12 11.1 1.4 0.19 10.4 1.4 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Tropomodulin PF03250.14 KFP22667.1 - 2.5e-43 147.5 2.5 2.5e-43 147.5 2.5 1.8 2 1 0 2 2 2 1 Tropomodulin LRR_6 PF13516.6 KFP22667.1 - 0.047 13.8 0.1 0.18 11.9 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich repeat DUF3644 PF12358.8 KFP22667.1 - 0.082 13.4 0.3 0.34 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) TUDOR PF00567.24 KFP22668.1 - 2.8e-63 211.4 0.8 3.6e-26 91.6 0.0 3.3 3 0 0 3 3 3 3 Tudor domain OST-HTH PF12872.7 KFP22668.1 - 0.00056 19.7 0.2 3.8 7.4 0.0 3.5 3 0 0 3 3 3 2 OST-HTH/LOTUS domain S_100 PF01023.19 KFP22671.1 - 1.3e-20 72.8 0.8 1.9e-20 72.3 0.8 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.6 KFP22671.1 - 0.00018 21.9 1.4 0.00041 20.7 1.4 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KFP22671.1 - 0.0044 16.5 1.7 0.011 15.3 0.2 2.4 3 0 0 3 3 3 1 EF hand AMP-binding PF00501.28 KFP22672.1 - 5.8e-95 318.4 0.4 9.9e-66 222.1 0.1 2.4 2 0 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KFP22672.1 - 3.8e-11 43.8 2.7 7.7e-11 42.8 2.7 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain AMP-binding_C PF13193.6 KFP22672.1 - 0.24 12.4 1.2 1 10.4 1.2 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain TSP_1 PF00090.19 KFP22673.1 - 7.4e-87 285.4 86.6 2.5e-17 62.8 6.9 6.7 6 0 0 6 6 6 6 Thrombospondin type 1 domain Spond_N PF06468.13 KFP22673.1 - 5.5e-72 241.9 0.2 1.2e-71 240.8 0.2 1.6 2 0 0 2 2 2 1 Spondin_N DUF3827 PF12877.7 KFP22676.1 - 8.2e-293 973.0 11.3 9.7e-293 972.7 7.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3827) NusA_N PF08529.11 KFP22676.1 - 0.13 12.6 0.7 53 4.2 0.0 3.3 3 0 0 3 3 3 0 NusA N-terminal domain Pkinase PF00069.25 KFP22677.1 - 1.2e-48 165.8 0.0 2.9e-48 164.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22677.1 - 5.7e-24 84.8 0.0 1.1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP22677.1 - 6.1e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFP22677.1 - 0.003 16.4 1.3 0.0039 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KFP22677.1 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFP22677.1 - 0.091 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KFP22677.1 - 0.13 11.8 0.2 3.4 7.2 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Suf PF05843.14 KFP22678.1 - 2.3e-84 283.9 13.6 7.7e-83 278.9 0.2 5.1 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFP22678.1 - 3.8e-06 27.3 0.9 0.095 13.6 0.0 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFP22678.1 - 8.3e-06 25.1 13.2 0.24 10.5 0.1 5.7 3 2 4 7 7 7 5 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KFP22678.1 - 0.0016 18.9 3.3 0.085 13.5 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22678.1 - 0.0062 17.0 1.7 0.11 13.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22678.1 - 0.098 13.3 0.6 0.58 10.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 KFP22678.1 - 7.3 6.6 7.5 13 5.9 0.0 4.5 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat DEP PF00610.21 KFP22679.1 - 1.5e-16 60.2 1.6 9.3e-16 57.6 0.2 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Gla PF00594.20 KFP22680.1 - 3.3e-19 68.8 6.8 3.3e-19 68.8 6.8 1.6 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain WBP-1 PF11669.8 KFP22680.1 - 0.0016 19.0 0.0 0.0039 17.8 0.0 1.6 2 0 0 2 2 2 1 WW domain-binding protein 1 Orthoreo_P10 PF07204.11 KFP22680.1 - 0.012 15.5 0.2 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 CD34_antigen PF06365.12 KFP22680.1 - 0.041 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Adeno_E3_CR2 PF02439.15 KFP22680.1 - 0.063 13.1 1.8 0.11 12.3 1.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KFP22680.1 - 0.096 13.6 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KFP22680.1 - 0.19 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Comm PF15957.5 KFP22680.1 - 0.92 9.9 3.3 5.3 7.4 3.3 2.1 1 1 0 1 1 1 0 Commissureless CCDC73 PF15818.5 KFP22681.1 - 0 1236.6 78.2 0 1236.5 78.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 73 family DUF1664 PF07889.12 KFP22681.1 - 2.1 8.4 34.2 0.043 13.9 3.9 5.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Lipoprotein_20 PF13942.6 KFP22681.1 - 4.6 7.1 33.0 0.31 10.9 8.3 3.9 2 2 1 3 3 3 0 YfhG lipoprotein Mst1_SARAH PF11629.8 KFP22681.1 - 8.5 6.5 16.5 0.19 11.9 1.2 4.2 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 PCI PF01399.27 KFP22682.1 - 7e-15 55.4 1.7 4.6e-14 52.8 1.0 2.4 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KFP22682.1 - 3.5e-12 45.8 2.9 6.7e-12 44.9 2.9 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix WT1 PF02165.15 KFP22683.1 - 5.6e-71 239.2 0.7 1.1e-70 238.3 0.7 1.5 1 0 0 1 1 1 1 Wilm's tumour protein zf-C2H2 PF00096.26 KFP22683.1 - 6.8e-16 57.7 38.4 8.9e-06 25.9 3.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP22683.1 - 6e-15 54.9 39.0 3.2e-07 30.5 2.9 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP22683.1 - 2.8e-08 33.9 33.2 0.0028 18.3 1.8 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 KFP22683.1 - 6.8e-05 23.4 12.9 0.0026 18.3 0.5 3.9 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KFP22683.1 - 0.00025 21.3 6.2 0.27 11.3 0.0 3.4 2 1 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFP22683.1 - 0.0012 19.1 12.9 0.028 14.7 3.2 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 KFP22683.1 - 0.016 15.6 20.5 0.023 15.1 2.0 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP22683.1 - 0.065 13.5 1.5 0.065 13.5 1.5 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding C1-set PF07654.15 KFP22683.1 - 0.4 11.1 5.5 3.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Ofd1_CTDD PF10637.9 KFP22683.1 - 0.51 9.7 4.1 0.77 9.1 1.0 2.0 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term zinc_ribbon_4 PF13717.6 KFP22683.1 - 0.58 10.1 8.1 21 5.2 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain CCAP PF11105.8 KFP22683.1 - 0.97 9.4 5.2 0.15 12.0 0.3 2.0 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a MCM_OB PF17207.3 KFP22683.1 - 1.6 8.6 11.4 5.1 7.0 3.5 3.0 1 1 1 2 2 2 0 MCM OB domain Apyrase PF06079.11 KFP22684.1 - 5.9e-84 281.7 1.0 7.3e-84 281.4 1.0 1.0 1 0 0 1 1 1 1 Apyrase C1q PF00386.21 KFP22685.1 - 2.9e-38 131.0 2.0 3.6e-38 130.6 2.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP22685.1 - 2.7e-08 33.4 13.0 4.1e-08 32.8 13.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_4 PF13853.6 KFP22686.1 - 1.4e-49 169.4 9.3 1.6e-49 169.1 9.3 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.21 KFP22686.1 - 2e-26 92.9 9.1 2.8e-26 92.4 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22686.1 - 0.00033 20.1 7.2 0.00083 18.8 7.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22686.1 - 0.0066 16.1 7.7 0.012 15.2 7.7 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3453 PF11935.8 KFP22687.1 - 3.1e-58 197.1 3.6 5.5e-58 196.3 0.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 KFP22687.1 - 1.5e-20 74.1 0.6 8.6e-20 71.6 0.0 2.5 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal Cnd1 PF12717.7 KFP22687.1 - 0.002 18.2 3.8 0.057 13.5 1.3 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFP22687.1 - 0.003 17.7 0.0 19 5.8 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.20 KFP22687.1 - 0.12 10.9 4.6 0.59 8.6 0.4 3.1 4 0 0 4 4 4 0 Adaptin N terminal region Glyco_hydro_1 PF00232.18 KFP22688.1 - 2.1e-162 540.7 6.6 2.4e-162 540.5 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KFP22688.1 - 0.023 13.9 1.1 0.52 9.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 DUF3377 PF11857.8 KFP22688.1 - 0.21 11.6 1.4 0.4 10.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Zwilch PF09817.9 KFP22689.1 - 2.5e-169 564.4 2.4 3.7e-169 563.9 2.4 1.2 1 1 0 1 1 1 1 RZZ complex, subunit zwilch DUF5601 PF18151.1 KFP22689.1 - 0.034 14.5 0.2 0.85 10.0 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) Pkinase PF00069.25 KFP22690.1 - 3.7e-62 210.1 0.0 4.7e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22690.1 - 1.4e-34 119.5 0.0 6.2e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP22690.1 - 5.9e-06 25.3 0.0 8.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFP22690.1 - 0.0054 15.7 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFP22690.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KFP22690.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Swi3 PF07962.12 KFP22691.1 - 1.6e-34 117.8 0.7 2.4e-34 117.1 0.2 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 HATPase_c_2 PF13581.6 KFP22691.1 - 0.089 12.8 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain RNB PF00773.19 KFP22692.1 - 2.3e-87 293.4 0.1 4e-87 292.6 0.1 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFP22692.1 - 3.9e-21 74.9 0.0 1.1e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KFP22692.1 - 4.6e-08 33.1 0.0 0.00014 21.9 0.0 3.2 2 1 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 KFP22692.1 - 3.1e-07 30.3 0.0 1e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KFP22692.1 - 7.1e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 KFP22692.1 - 0.11 12.2 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain EMI PF07546.13 KFP22693.1 - 1.8e-17 63.8 9.3 1.8e-17 63.8 9.3 1.8 2 0 0 2 2 2 1 EMI domain hEGF PF12661.7 KFP22693.1 - 0.018 15.6 5.8 0.018 15.6 5.8 3.4 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_2 PF07974.13 KFP22693.1 - 0.02 15.3 11.1 0.02 15.3 11.1 2.4 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 KFP22694.1 - 2.9e-54 181.0 298.2 0.00034 20.7 15.9 16.8 7 5 9 16 16 16 16 Laminin EGF domain hEGF PF12661.7 KFP22694.1 - 3.7e-13 49.6 262.4 0.00042 20.8 5.2 22.5 22 2 1 23 23 23 13 Human growth factor-like EGF EGF_2 PF07974.13 KFP22694.1 - 5.3e-10 39.5 370.4 0.012 15.9 10.1 26.4 23 7 3 26 26 26 12 EGF-like domain EGF PF00008.27 KFP22694.1 - 1e-05 25.7 325.8 0.006 16.9 13.2 22.7 23 1 0 23 23 23 13 EGF-like domain Syndecan PF01034.20 KFP22694.1 - 0.048 13.6 0.3 0.085 12.8 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain Meckelin PF09773.9 KFP22694.1 - 0.092 10.8 0.0 0.35 8.9 0.0 2.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF2207 PF09972.9 KFP22694.1 - 0.28 9.9 0.0 0.38 9.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KFP22694.1 - 1.3 8.5 4.2 2.3 7.7 4.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAP1_N PF04849.13 KFP22695.1 - 0.0024 17.2 18.5 0.0024 17.2 18.5 5.8 1 1 4 5 5 5 1 HAP1 N-terminal conserved region SF3A3 PF16837.5 KFP22695.1 - 0.5 10.9 5.9 1.1 9.8 0.2 3.5 3 1 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TMP_2 PF06791.13 KFP22695.1 - 0.86 9.2 9.7 1.1 8.9 3.0 3.0 2 1 0 2 2 2 0 Prophage tail length tape measure protein DUF89 PF01937.19 KFP22696.1 - 2.6e-124 414.7 1.0 3e-124 414.6 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 KRBA1 PF15287.6 KFP22696.1 - 0.044 13.5 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 KRBA1 family repeat DUF155 PF02582.14 KFP22697.1 - 3.3e-47 160.8 2.7 4.8e-47 160.3 2.7 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BTB PF00651.31 KFP22698.1 - 4.3e-19 68.8 0.2 9e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.26 KFP22698.1 - 3.2e-14 52.5 30.2 0.00023 21.5 1.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP22698.1 - 2.9e-12 46.4 19.9 0.00013 22.3 2.9 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP22698.1 - 3.2e-09 36.8 27.2 0.012 16.4 1.3 5.1 5 0 0 5 5 4 3 C2H2-type zinc finger zf-met PF12874.7 KFP22698.1 - 1.1e-08 35.2 21.9 0.16 12.4 1.5 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFP22698.1 - 5.8e-07 29.6 16.6 0.014 15.7 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFP22698.1 - 7.1e-05 23.5 8.5 0.21 12.3 0.0 4.0 2 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KFP22698.1 - 0.036 14.5 15.9 6.2 7.3 0.1 4.5 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KFP22698.1 - 0.037 14.0 30.5 0.74 9.9 0.5 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFP22698.1 - 0.098 12.6 19.0 0.36 10.8 0.4 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type FYVE PF01363.21 KFP22698.1 - 0.18 12.0 16.5 5.9 7.1 0.0 3.9 3 1 0 3 3 3 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KFP22698.1 - 0.24 11.8 17.5 4.1 7.8 0.3 3.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KFP22698.1 - 1.3 9.3 21.7 0.31 11.2 2.7 4.7 4 1 0 4 4 4 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 KFP22698.1 - 1.4 9.1 16.2 5 7.3 0.1 4.4 4 0 0 4 4 4 0 Zinc ribbon domain zf-CCHC_2 PF13696.6 KFP22698.1 - 3.6 7.5 15.9 10 6.0 2.2 3.7 3 0 0 3 3 3 0 Zinc knuckle zf_UBZ PF18439.1 KFP22698.1 - 5.4 6.7 12.4 24 4.6 0.4 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PhnA PF03831.14 KFP22699.1 - 0.11 12.3 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 PhnA domain PKcGMP_CC PF16808.5 KFP22700.1 - 0.11 12.4 2.2 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WSK PF03832.13 KFP22701.1 - 1.8e-15 56.3 9.1 2.3e-13 49.6 2.0 3.8 4 0 0 4 4 4 2 WSK motif RhoGEF PF00621.20 KFP22702.1 - 1.3e-44 152.6 1.8 1.3e-44 152.6 1.8 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 KFP22702.1 - 0.00016 22.1 0.2 0.00059 20.3 0.1 2.0 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 KFP22702.1 - 0.017 15.4 0.1 0.017 15.4 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 KFP22702.1 - 0.068 13.1 0.2 0.27 11.2 0.2 2.0 1 0 0 1 1 1 0 PH domain PH_16 PF17838.1 KFP22702.1 - 0.68 9.8 4.8 0.58 10.0 0.6 2.9 3 1 0 3 3 3 0 PH domain Syntaxin_2 PF14523.6 KFP22702.1 - 1.1 9.6 5.2 1 9.8 0.1 2.7 2 0 0 2 2 2 0 Syntaxin-like protein Nitroreductase PF00881.24 KFP22703.1 - 3.9e-21 75.8 0.0 5.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KFP22703.1 - 0.00086 18.9 0.0 7.7 6.0 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase Ldl_recept_a PF00057.18 KFP22704.1 - 1.3e-07 31.7 10.6 2.5e-07 30.8 10.6 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A PCMT PF01135.19 KFP22706.1 - 1.8e-81 272.9 0.0 2e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFP22706.1 - 4.4e-07 30.5 0.0 7.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFP22706.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFP22706.1 - 6.4e-05 23.5 0.1 0.00018 22.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFP22706.1 - 8e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KFP22706.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 KFP22706.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFP22706.1 - 0.0018 18.2 0.0 0.0055 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFP22706.1 - 0.026 14.1 0.1 0.037 13.6 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KFP22706.1 - 0.073 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 KFP22706.1 - 0.092 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 KFP22706.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KFP22706.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase WD40 PF00400.32 KFP22707.1 - 1.8e-06 28.5 6.0 0.0031 18.3 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat CPSF_A PF03178.15 KFP22707.1 - 2.8e-05 23.6 0.1 5.1e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 CPSF A subunit region GHD PF17834.1 KFP22707.1 - 0.03 14.4 0.0 14 5.8 0.0 2.7 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Pkinase PF00069.25 KFP22708.1 - 1.7e-61 207.9 0.4 1.5e-39 136.0 0.0 3.1 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22708.1 - 2.5e-28 99.1 0.0 5.3e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UBA PF00627.31 KFP22708.1 - 2.1e-10 40.3 0.8 2.1e-10 40.3 0.8 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Haspin_kinase PF12330.8 KFP22708.1 - 0.00069 18.7 0.1 0.0013 17.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFP22708.1 - 0.0036 16.6 0.1 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFP22708.1 - 0.0038 17.2 0.5 0.024 14.6 0.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family UBA_3 PF09288.10 KFP22708.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Pox_ser-thr_kin PF05445.11 KFP22708.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cas_Cas6 PF01881.16 KFP22708.1 - 0.12 13.0 1.6 0.21 12.1 1.6 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas6 HOIP-UBA PF16678.5 KFP22708.1 - 0.14 12.1 0.7 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair Pkinase_C PF00433.24 KFP22708.1 - 0.42 11.4 3.9 0.26 12.0 0.5 2.5 2 0 0 2 2 2 0 Protein kinase C terminal domain AAA PF00004.29 KFP22709.1 - 1.1e-39 135.8 0.0 2.1e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP22709.1 - 9.9e-17 60.5 1.2 9.7e-16 57.3 1.2 2.7 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KFP22709.1 - 5.7e-09 35.9 0.2 2.3e-08 33.9 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KFP22709.1 - 6.3e-06 26.4 0.2 1.8e-05 25.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFP22709.1 - 1.3e-05 25.0 0.0 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFP22709.1 - 4.3e-05 23.7 0.0 0.00015 21.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KFP22709.1 - 0.00053 20.0 0.3 0.0039 17.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFP22709.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KFP22709.1 - 0.0015 18.3 0.0 0.0082 15.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KFP22709.1 - 0.0019 18.3 0.0 0.0055 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KFP22709.1 - 0.0033 16.8 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFP22709.1 - 0.0042 17.4 1.5 0.079 13.2 0.4 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP22709.1 - 0.0043 17.4 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFP22709.1 - 0.0046 16.5 0.2 0.012 15.2 0.2 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KFP22709.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KFP22709.1 - 0.0076 15.6 0.5 1.2 8.5 0.1 2.6 2 1 1 3 3 2 1 KaiC PhoH PF02562.16 KFP22709.1 - 0.023 14.1 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KFP22709.1 - 0.025 15.1 0.8 0.16 12.5 0.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFP22709.1 - 0.025 14.4 0.6 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFP22709.1 - 0.061 13.8 0.0 0.4 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KFP22709.1 - 0.062 13.7 0.4 0.17 12.3 0.0 2.1 2 1 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 KFP22709.1 - 0.16 11.7 0.0 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KFP22709.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 KFP22709.1 - 0.17 11.8 0.2 0.57 10.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NACHT PF05729.12 KFP22709.1 - 0.17 11.8 0.1 0.49 10.3 0.1 1.7 1 1 0 1 1 1 0 NACHT domain TPR_8 PF13181.6 KFP22709.1 - 0.19 12.0 0.8 0.51 10.7 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat AAA_24 PF13479.6 KFP22709.1 - 0.22 11.2 1.8 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 KFP22709.1 - 0.26 10.9 1.8 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase TPR_2 PF07719.17 KFP22709.1 - 0.33 11.2 1.7 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 KFP22712.1 - 2.3e-30 106.0 0.3 2.3e-30 106.0 0.3 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFP22712.1 - 5.8e-18 64.5 0.0 1.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_Zc3h12a PF11977.8 KFP22713.1 - 1.5e-64 216.5 0.0 2.1e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain UBA_6 PF18039.1 KFP22713.1 - 2.3e-20 72.3 0.2 4.5e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain zf-CCCH_4 PF18044.1 KFP22713.1 - 1.5e-05 24.7 5.5 1.5e-05 24.7 5.5 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KFP22713.1 - 0.0061 16.5 5.9 0.013 15.4 4.0 2.4 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRORP PF16953.5 KFP22713.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P zf-CCCH_2 PF14608.6 KFP22713.1 - 0.12 12.9 9.6 0.25 11.9 9.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Omega-toxin PF06357.11 KFP22713.1 - 0.34 10.7 3.7 0.78 9.6 3.7 1.5 1 0 0 1 1 1 0 Omega-atracotoxin zf_CCCH_4 PF18345.1 KFP22713.1 - 0.45 10.6 5.1 1.5 9.0 4.4 2.2 1 1 1 2 2 2 0 Zinc finger domain Sulfotransfer_2 PF03567.14 KFP22714.1 - 3.3e-33 115.6 1.2 4.3e-33 115.3 1.2 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KFP22714.1 - 4.7e-08 32.3 0.3 6.5e-08 31.9 0.3 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase LLGL PF08366.13 KFP22717.1 - 5.6e-34 116.6 0.0 1.5e-33 115.3 0.0 1.8 1 0 0 1 1 1 1 LLGL2 ANAPC4_WD40 PF12894.7 KFP22717.1 - 1.7e-11 44.2 1.2 0.028 14.7 0.1 6.2 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFP22717.1 - 1.1e-08 35.5 11.6 0.0033 18.2 0.7 6.6 7 1 0 7 7 7 2 WD domain, G-beta repeat Lgl_C PF08596.10 KFP22717.1 - 1.9e-07 30.1 0.1 7e-06 25.0 0.0 3.2 3 1 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40_like PF17005.5 KFP22717.1 - 0.0022 17.4 0.0 0.02 14.3 0.0 2.4 1 1 0 1 1 1 1 WD40-like domain Synaptobrevin PF00957.21 KFP22717.1 - 0.0025 17.6 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 Synaptobrevin ELYS-bb PF16687.5 KFP22717.1 - 0.0051 15.5 0.0 9.4 4.7 0.0 3.3 2 1 1 3 3 3 1 beta-propeller of ELYS nucleoporin Frtz PF11768.8 KFP22717.1 - 0.006 15.0 0.1 0.016 13.5 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 KFP22717.1 - 0.011 15.1 0.0 7.4 5.7 0.0 3.3 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.11 KFP22717.1 - 0.077 12.7 0.0 3.4 7.3 0.0 3.2 2 1 2 4 4 4 0 TUP1-like enhancer of split Globin PF00042.22 KFP22718.1 - 3.1e-08 34.2 0.0 5.9e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Globin IQ PF00612.27 KFP22718.1 - 0.031 14.0 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif MGTL PF17059.5 KFP22719.1 - 1.5 8.8 5.7 3.7 7.5 5.7 1.7 1 0 0 1 1 1 0 MgtA leader peptide Ras PF00071.22 KFP22721.1 - 1.2e-38 132.3 0.0 1.4e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22721.1 - 4.1e-28 98.0 0.0 5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22721.1 - 2e-09 37.1 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFP22721.1 - 2.6e-06 27.0 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFP22721.1 - 0.00021 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KFP22721.1 - 0.002 17.7 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KFP22721.1 - 0.0022 18.2 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFP22721.1 - 0.0031 17.1 0.0 0.073 12.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP22721.1 - 0.0055 16.5 0.0 1.8 8.3 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KFP22721.1 - 0.043 14.2 0.1 0.068 13.5 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KFP22721.1 - 0.049 13.0 0.0 0.27 10.6 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KFP22721.1 - 0.053 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KFP22721.1 - 0.071 12.3 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KFP22721.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFP22721.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFP22721.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KFP22721.1 - 0.13 12.7 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFP22721.1 - 0.17 11.8 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KFP22721.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ANF_receptor PF01094.28 KFP22722.1 - 2.7e-71 240.5 0.0 1e-46 159.7 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region 7tm_3 PF00003.22 KFP22722.1 - 1.1e-56 192.2 27.5 1.6e-56 191.7 27.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GluR_Homer-bdg PF10606.9 KFP22722.1 - 3.7e-25 87.9 9.4 1.1e-24 86.4 9.4 1.9 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.14 KFP22722.1 - 2.2e-15 56.3 10.4 4.8e-15 55.3 10.4 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF5438 PF17506.2 KFP22722.1 - 0.067 13.5 0.4 0.22 11.9 0.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5438) F-box_4 PF15966.5 KFP22724.1 - 3e-50 169.0 0.7 3e-50 169.0 0.7 2.2 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 KFP22724.1 - 2.1e-38 130.7 15.0 2.1e-38 130.7 15.0 2.9 3 1 0 3 3 3 1 TRAF-like zinc-finger F-box PF00646.33 KFP22724.1 - 2.1e-07 30.6 0.8 5.9e-07 29.2 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFP22724.1 - 2e-06 27.5 0.2 6.1e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.18 KFP22724.1 - 0.0043 17.7 1.9 0.0043 17.7 1.9 4.3 6 0 0 6 6 6 1 TRAF-type zinc finger DUF4644 PF15486.6 KFP22724.1 - 0.035 13.9 0.8 4.9 6.9 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4644) NAD_binding_8 PF13450.6 KFP22724.1 - 0.12 12.7 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DSPc PF00782.20 KFP22725.1 - 9.1e-14 51.4 0.0 1.8e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KFP22725.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.12 KFP22725.1 - 0.052 13.2 0.0 0.083 12.6 0.0 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AAA_25 PF13481.6 KFP22725.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AlaDh_PNT_N PF05222.15 KFP22725.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Spectrin PF00435.21 KFP22726.1 - 7.7e-17 61.7 18.1 8.4e-11 42.3 5.9 2.9 2 1 1 3 3 3 2 Spectrin repeat EFhand_Ca_insen PF08726.10 KFP22726.1 - 0.031 14.4 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 Ca2+ insensitive EF hand MnmE_helical PF12631.7 KFP22726.1 - 0.11 12.6 4.5 0.15 12.2 4.5 1.1 1 0 0 1 1 1 0 MnmE helical domain NPV_P10 PF05531.12 KFP22726.1 - 0.19 12.2 14.3 0.34 11.4 0.5 4.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Uteroglobin PF01099.17 KFP22726.1 - 0.26 11.6 3.2 1.4 9.3 1.8 2.5 2 0 0 2 2 2 0 Uteroglobin family DUF948 PF06103.11 KFP22726.1 - 0.29 11.4 7.8 36 4.7 0.0 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DASH_Dam1 PF08653.10 KFP22726.1 - 0.36 10.7 3.8 9.3 6.1 0.1 4.1 4 0 0 4 4 4 0 DASH complex subunit Dam1 FAD_SOX PF18371.1 KFP22726.1 - 2.1 8.8 5.4 32 5.0 0.0 3.3 2 2 2 4 4 4 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Rab5-bind PF09311.11 KFP22726.1 - 2.1 7.7 19.1 1.6 8.1 5.1 2.8 2 1 1 3 3 3 0 Rabaptin-like protein HetR_C PF18460.1 KFP22726.1 - 2.9 7.9 7.7 0.62 10.0 0.1 3.3 3 1 1 4 4 4 0 Heterocyst differentiation regulator C-terminal Hood domain CorA PF01544.18 KFP22726.1 - 6.4 6.0 13.2 1.4 8.2 6.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Phage_GP20 PF06810.11 KFP22726.1 - 8.9 6.1 12.9 9.5 6.0 0.8 3.4 2 2 0 2 2 2 0 Phage minor structural protein GP20 Spectrin PF00435.21 KFP22727.1 - 2.4e-44 150.1 84.0 3.2e-14 53.3 5.2 7.7 7 1 0 7 7 7 7 Spectrin repeat CH PF00307.31 KFP22727.1 - 1.1e-43 147.9 2.8 7.2e-21 74.4 0.1 4.0 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KFP22727.1 - 4.5e-05 23.2 0.0 0.027 14.3 0.0 3.2 2 0 0 2 2 2 2 CAMSAP CH domain Pfg27 PF09216.10 KFP22727.1 - 0.098 12.5 3.6 0.24 11.2 0.3 3.1 3 0 0 3 3 3 0 Pfg27 DUF3288 PF11691.8 KFP22727.1 - 0.26 11.4 11.2 3.6 7.7 0.1 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3288) AbiEi_1 PF09407.10 KFP22727.1 - 0.41 10.9 3.2 8.2 6.7 0.0 3.9 3 1 0 4 4 4 0 AbiEi antitoxin C-terminal domain Syntaxin PF00804.25 KFP22728.1 - 2.2e-64 216.8 15.1 2.2e-64 216.8 15.1 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KFP22728.1 - 7.5e-06 25.8 0.2 5.2e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 SNARE domain Herpes_BLRF2 PF05812.12 KFP22728.1 - 0.0024 18.0 2.8 0.012 15.7 0.9 2.3 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein DUF1217 PF06748.12 KFP22728.1 - 0.021 14.9 0.2 0.05 13.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) DivIC PF04977.15 KFP22728.1 - 0.3 10.9 5.3 0.14 11.9 0.4 2.7 3 0 0 3 3 3 0 Septum formation initiator HisKA_3 PF07730.13 KFP22728.1 - 0.3 11.6 2.3 5.5 7.6 0.2 3.4 2 2 2 4 4 4 0 Histidine kinase FUSC PF04632.12 KFP22728.1 - 0.34 9.4 0.3 0.32 9.5 0.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spectrin PF00435.21 KFP22728.1 - 0.45 11.0 8.6 0.36 11.3 2.6 2.7 2 2 0 2 2 2 0 Spectrin repeat HMMR_C PF15908.5 KFP22728.1 - 0.47 10.7 6.2 2.9 8.1 0.6 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal SOAR PF16533.5 KFP22728.1 - 5 7.2 8.4 0.51 10.3 0.3 3.0 3 1 1 4 4 4 0 STIM1 Orai1-activating region Forkhead PF00250.18 KFP22730.1 - 1.5e-38 130.9 0.2 2.8e-38 130.1 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain HNF_C PF09354.10 KFP22730.1 - 1.5e-26 93.2 12.0 1.5e-26 93.2 12.0 4.0 3 1 0 3 3 3 1 HNF3 C-terminal domain Forkhead_N PF08430.12 KFP22730.1 - 1e-24 87.7 45.6 1e-24 87.7 45.6 2.3 2 0 0 2 2 2 1 Forkhead N-terminal region SelP_N PF04592.14 KFP22730.1 - 1.5 8.2 8.5 2.4 7.5 8.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SNAP PF14938.6 KFP22731.1 - 5.7e-68 229.4 16.5 9.7e-68 228.6 16.5 1.4 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KFP22731.1 - 0.00051 20.6 1.4 0.004 17.8 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22731.1 - 0.0013 19.0 1.7 0.0013 19.0 1.7 3.2 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22731.1 - 0.0082 16.1 8.1 0.06 13.4 0.0 4.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22731.1 - 0.31 12.0 4.7 17 6.6 0.2 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22731.1 - 1.4 9.2 12.3 1.8 8.8 0.9 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat zf_CCCH_4 PF18345.1 KFP22732.1 - 3.4e-14 52.4 29.4 1.8e-07 31.0 2.8 3.6 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 KFP22732.1 - 2.9e-13 49.3 20.6 0.00023 20.9 4.9 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 KFP22732.1 - 9e-11 41.4 23.0 4.1e-05 23.4 1.7 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KFP22732.1 - 1e-06 28.9 21.9 0.021 15.3 1.3 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFP22732.1 - 1.2e-05 25.5 15.6 0.00022 21.4 8.0 2.7 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 KFP22732.1 - 0.0011 19.7 12.6 0.0032 18.2 1.7 5.0 3 1 2 5 5 5 3 Torus domain Pkinase_Tyr PF07714.17 KFP22733.1 - 1e-91 306.8 0.0 1.4e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP22733.1 - 1.6e-38 132.6 0.0 2.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 KFP22733.1 - 5.4e-15 55.5 0.4 1.8e-07 31.4 0.2 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.6 KFP22733.1 - 4.4e-14 52.6 0.1 4.5e-07 30.1 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KFP22733.1 - 3.3e-13 50.0 1.9 2.3e-07 31.3 0.1 3.3 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP22733.1 - 5.6e-11 42.4 0.0 0.00079 19.5 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KFP22733.1 - 1e-09 38.4 0.0 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KFP22733.1 - 0.00053 20.1 0.2 9.3 6.5 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP22733.1 - 0.051 13.6 0.2 6.7 6.8 0.0 3.1 2 2 0 2 2 2 0 CD80-like C2-set immunoglobulin domain APC1_C PF18122.1 KFP22734.1 - 4.3e-39 134.1 0.5 1e-38 132.9 0.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KFP22734.1 - 2.5e-12 47.5 10.6 3.4e-12 47.1 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KFP22734.1 - 4.2e-06 26.9 16.1 0.0025 18.2 0.0 5.6 6 0 0 6 6 6 3 Proteasome/cyclosome repeat V-set PF07686.17 KFP22735.1 - 5.7e-12 45.8 3.5 1.5e-10 41.2 0.2 2.4 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KFP22735.1 - 1.1e-10 41.9 4.9 0.0002 21.9 1.4 2.8 2 1 1 3 3 3 2 Immunoglobulin domain ig PF00047.25 KFP22735.1 - 3e-10 40.1 6.1 1.2e-05 25.4 0.2 3.8 2 2 1 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP22735.1 - 7.7e-10 38.7 0.1 3.5e-09 36.6 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KFP22735.1 - 4.4e-08 33.1 0.4 0.0096 16.0 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP22735.1 - 8.9e-07 29.2 3.2 0.0016 18.8 0.8 2.8 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 KFP22735.1 - 5.6e-05 23.4 4.0 0.00024 21.4 0.1 3.1 2 1 1 3 3 3 1 Immunoglobulin C1-set domain DUF2207 PF09972.9 KFP22735.1 - 0.0037 16.1 0.0 0.0053 15.6 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Lep_receptor_Ig PF06328.11 KFP22735.1 - 0.0057 16.6 6.2 0.0088 16.0 0.0 3.1 3 1 1 4 4 4 1 Ig-like C2-type domain DUF4366 PF14283.6 KFP22735.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF347 PF03988.12 KFP22735.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Fim-adh_lectin PF09222.10 KFP22735.1 - 0.048 13.2 0.3 0.086 12.3 0.3 1.4 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain MLANA PF14991.6 KFP22735.1 - 0.11 12.8 3.9 0.2 11.9 1.6 2.5 2 1 1 3 3 3 0 Protein melan-A LapA_dom PF06305.11 KFP22735.1 - 0.46 10.3 2.3 1.1 9.1 2.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PIP49_C PF12260.8 KFP22736.1 - 4.1e-42 144.0 0.0 6.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Glyco_trans_4_4 PF13579.6 KFP22736.1 - 0.039 14.4 0.2 0.061 13.8 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain JmjC PF02373.22 KFP22737.1 - 1.3e-31 109.4 1.9 1.3e-31 109.4 1.9 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_1 PF00515.28 KFP22737.1 - 1e-29 101.1 19.1 2e-06 27.4 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22737.1 - 2.3e-19 67.9 17.8 0.0012 18.8 0.4 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22737.1 - 3.4e-15 54.9 16.6 0.0017 18.4 0.7 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22737.1 - 3.7e-15 56.3 1.2 0.0011 19.5 1.2 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22737.1 - 5.6e-12 45.8 9.8 0.021 15.1 0.4 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22737.1 - 9.2e-12 44.5 5.9 0.0046 17.2 0.0 5.5 7 0 0 7 7 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22737.1 - 4.7e-07 29.9 1.8 0.0076 16.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22737.1 - 1e-06 29.0 4.5 1.5 9.8 0.0 5.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22737.1 - 1.1e-06 29.0 10.7 0.032 14.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22737.1 - 1.8e-05 24.4 9.7 1.1 9.5 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22737.1 - 0.00014 21.4 16.4 0.089 12.5 0.0 7.2 4 3 4 8 8 8 2 TPR repeat SNAP PF14938.6 KFP22737.1 - 0.083 12.3 13.8 0.048 13.1 1.9 3.1 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 KFP22737.1 - 0.085 12.1 6.4 0.5 9.5 2.5 3.4 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP22737.1 - 0.6 10.4 0.0 0.6 10.4 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFP22737.1 - 5 8.0 13.9 45 5.0 0.1 7.1 9 0 0 9 9 7 0 Tetratricopeptide repeat Peptidase_C12 PF01088.21 KFP22738.1 - 6.4e-60 202.5 0.0 7.2e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ISG65-75 PF11727.8 KFP22738.1 - 0.16 11.2 0.2 0.21 10.8 0.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein COMM_domain PF07258.14 KFP22739.1 - 8.1e-17 61.1 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 COMM domain CDT1_C PF16679.5 KFP22739.1 - 0.022 15.2 0.0 0.094 13.2 0.0 2.0 1 1 1 2 2 2 0 DNA replication factor Cdt1 C-terminal domain MIF4G_like_2 PF09090.11 KFP22739.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.4 1 1 1 2 2 2 0 MIF4G like RabGAP-TBC PF00566.18 KFP22740.1 - 1.1e-51 175.6 0.9 1.1e-51 175.6 0.9 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3350 PF11830.8 KFP22740.1 - 1.7e-29 101.9 3.5 5.7e-29 100.2 3.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) PID PF00640.23 KFP22740.1 - 7.8e-08 32.4 0.4 1.3e-06 28.5 0.5 2.5 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) Laminin_I PF06008.14 KFP22740.1 - 0.004 16.9 6.0 0.004 16.9 6.0 2.0 2 0 0 2 2 2 1 Laminin Domain I RecR PF02132.15 KFP22740.1 - 0.022 14.3 0.9 0.08 12.5 0.9 2.0 1 0 0 1 1 1 0 RecR protein PTB PF08416.13 KFP22740.1 - 0.054 13.7 0.4 0.25 11.5 0.2 2.3 2 0 0 2 2 2 0 Phosphotyrosine-binding domain DUF4249 PF14054.6 KFP22740.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) TSP_NTD PF17804.1 KFP22740.1 - 0.67 10.2 8.6 0.16 12.2 1.6 2.5 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Plk4_PB2 PF18409.1 KFP22740.1 - 7 7.4 9.1 4.2 8.1 0.1 4.1 4 0 0 4 4 4 0 Polo-like Kinase 4 Polo Box 2 KR PF08659.10 KFP22741.1 - 4.2e-53 179.9 0.0 1.1e-52 178.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KFP22741.1 - 1.7e-48 165.8 0.0 2.9e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFP22741.1 - 1.8e-33 115.0 0.1 7e-33 113.2 0.1 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFP22741.1 - 8.2e-27 94.2 0.0 1.6e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFP22741.1 - 4e-15 56.3 0.0 1e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFP22741.1 - 2.9e-12 46.5 0.1 1.7e-11 44.0 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP22741.1 - 3.8e-07 29.9 0.0 9.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFP22741.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ras PF00071.22 KFP22743.1 - 9.5e-49 165.1 0.1 1.1e-48 164.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22743.1 - 1.6e-27 96.1 0.0 2.3e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22743.1 - 4.8e-13 48.9 0.1 5.4e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP22743.1 - 0.023 14.2 0.1 0.054 13.0 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP22743.1 - 0.064 13.0 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Homeobox_KN PF05920.11 KFP22744.1 - 0.0009 19.1 0.6 0.002 18.0 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain DMAP_binding PF06464.11 KFP22744.1 - 0.3 11.9 2.1 5.5 7.9 2.1 2.5 1 1 0 1 1 1 0 DMAP1-binding Domain Guanylate_kin PF00625.21 KFP22745.1 - 9.9e-51 172.0 0.4 2.9e-49 167.2 0.4 2.2 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.16 KFP22745.1 - 2.5e-25 88.0 8.5 2.7e-13 49.4 1.4 2.7 3 0 0 3 3 3 2 L27 domain PDZ PF00595.24 KFP22745.1 - 2.3e-12 47.1 0.8 6e-12 45.8 0.8 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFP22745.1 - 9.1e-10 38.2 0.2 4.7e-09 36.0 0.2 2.2 2 0 0 2 2 2 1 PDZ domain SH3_2 PF07653.17 KFP22745.1 - 4.9e-07 29.3 0.0 1.3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP22745.1 - 1.1e-06 28.1 0.3 9.2e-06 25.2 0.2 2.5 2 1 0 2 2 2 1 SH3 domain PDZ_2 PF13180.6 KFP22745.1 - 0.00011 22.5 0.1 0.00036 20.8 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KFP22745.1 - 0.0028 17.5 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Seryl_tRNA_N PF02403.22 KFP22746.1 - 0.0011 19.1 7.7 0.021 15.1 0.3 2.0 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 KFP22746.1 - 0.002 17.8 5.7 0.0024 17.5 5.7 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF2968 PF11180.8 KFP22746.1 - 0.0032 17.1 3.2 0.0039 16.9 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Cut8 PF08559.10 KFP22746.1 - 0.0055 16.3 1.5 0.0065 16.1 1.5 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein ADIP PF11559.8 KFP22746.1 - 0.0057 16.7 7.4 0.007 16.5 7.4 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 KFP22746.1 - 0.0098 15.7 8.7 0.047 13.5 4.7 2.0 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HMMR_N PF15905.5 KFP22746.1 - 0.011 15.2 12.9 0.012 15.1 12.9 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 KFP22746.1 - 0.013 16.1 12.0 0.018 15.6 11.3 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Baculo_gp41 PF04700.12 KFP22746.1 - 0.02 14.7 0.3 0.022 14.5 0.3 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DUF3523 PF12037.8 KFP22746.1 - 0.028 13.8 4.9 0.031 13.7 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) GAS PF13851.6 KFP22746.1 - 0.036 13.4 12.5 0.22 10.9 12.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KFP22746.1 - 0.046 13.0 4.8 0.051 12.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 KFP22746.1 - 0.054 13.8 2.4 0.87 9.9 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CRIC_ras_sig PF10534.9 KFP22746.1 - 0.065 13.4 2.2 0.08 13.1 0.4 2.0 1 1 1 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF4140 PF13600.6 KFP22746.1 - 0.066 13.6 0.5 0.066 13.6 0.5 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Takusan PF04822.13 KFP22746.1 - 0.069 13.0 8.0 1.5 8.8 0.2 2.3 1 1 1 2 2 2 0 Takusan UPF0242 PF06785.11 KFP22746.1 - 0.073 13.2 7.5 0.085 13.0 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 KFP22746.1 - 0.089 12.6 3.8 0.13 12.1 3.8 1.3 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DivIVA PF05103.13 KFP22746.1 - 0.091 12.8 6.9 0.13 12.4 6.9 1.2 1 0 0 1 1 1 0 DivIVA protein Nup88 PF10168.9 KFP22746.1 - 0.093 10.5 7.8 0.11 10.3 7.8 1.0 1 0 0 1 1 1 0 Nuclear pore component ZapB PF06005.12 KFP22746.1 - 0.1 13.1 10.9 0.22 12.0 10.8 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.11 KFP22746.1 - 0.1 11.4 11.6 1 8.2 5.1 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 KFP22746.1 - 0.1 13.0 6.5 0.15 12.5 6.5 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Herpes_UL6 PF01763.16 KFP22746.1 - 0.11 11.0 4.0 0.13 10.8 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like SseC PF04888.12 KFP22746.1 - 0.18 11.3 2.8 0.22 11.1 2.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF5320 PF17253.2 KFP22746.1 - 0.2 12.7 1.3 0.39 11.8 1.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CREPT PF16566.5 KFP22746.1 - 0.4 10.8 8.2 0.62 10.2 7.7 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DrrA_P4M PF14860.6 KFP22746.1 - 0.45 10.4 6.3 0.51 10.2 4.3 1.9 1 1 1 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain TMPIT PF07851.13 KFP22746.1 - 0.5 9.6 5.1 0.56 9.4 5.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spore_III_AB PF09548.10 KFP22746.1 - 0.55 10.3 7.3 3.9 7.6 6.8 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SlyX PF04102.12 KFP22746.1 - 0.74 10.5 6.2 1.8 9.2 5.6 2.0 1 1 1 2 2 2 0 SlyX Lge1 PF11488.8 KFP22746.1 - 1 9.6 11.5 4 7.7 0.4 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Spc24 PF08286.11 KFP22746.1 - 2 8.7 7.9 3.3 8.0 7.7 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KFP22746.1 - 7.5 6.4 10.2 7.7 6.4 7.7 2.2 1 1 1 2 2 2 0 Septum formation initiator WW PF00397.26 KFP22747.1 - 1.4e-09 37.9 1.1 3e-09 36.8 1.1 1.5 1 0 0 1 1 1 1 WW domain BAMBI PF06211.12 KFP22748.1 - 2.2e-46 156.5 11.0 2.2e-46 156.5 11.0 1.6 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain LapA_dom PF06305.11 KFP22748.1 - 0.046 13.5 0.9 0.077 12.8 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 KFP22748.1 - 0.09 13.7 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain JIP_LZII PF16471.5 KFP22748.1 - 0.13 12.5 0.3 26 5.1 0.3 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II KASH PF10541.9 KFP22748.1 - 0.91 9.8 3.9 6.4 7.1 0.2 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain DUF4462 PF14692.6 KFP22750.1 - 0.17 11.3 0.2 0.54 9.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP22751.1 - 0.17 11.3 0.2 0.54 9.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) DUF4462 PF14692.6 KFP22752.1 - 0.17 11.3 0.2 0.54 9.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Pkinase PF00069.25 KFP22756.1 - 6.8e-49 166.6 0.0 1.2e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22756.1 - 2.1e-25 89.5 0.0 4.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP22756.1 - 1.6e-05 23.9 0.0 2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFP22756.1 - 0.013 15.4 0.1 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFP22756.1 - 0.039 13.3 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KFP22756.1 - 0.077 12.6 0.1 0.22 11.1 0.1 1.7 1 1 1 2 2 2 0 RIO1 family RL PF17797.1 KFP22757.1 - 6.5e-34 115.7 0.0 1.3e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 RL domain PAP_assoc PF03828.19 KFP22757.1 - 8.8e-06 25.8 0.1 2.6e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase JCAD PF15351.6 KFP22759.1 - 0 1800.1 60.7 0 1799.9 60.7 1.0 1 0 0 1 1 1 1 Junctional protein associated with coronary artery disease Gelsolin PF00626.22 KFP22760.1 - 2e-20 72.5 0.5 1.1e-05 25.3 0.0 5.7 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.19 KFP22760.1 - 5.5e-16 58.3 0.1 1.5e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 Villin headpiece domain DUF4695 PF15766.5 KFP22760.1 - 2.3e-08 34.2 6.9 0.012 15.8 0.0 4.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4695) zf-H2C2_2 PF13465.6 KFP22761.1 - 2e-08 34.3 29.9 0.00018 21.8 4.6 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP22761.1 - 0.00052 20.6 46.6 0.038 14.8 3.3 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP22761.1 - 0.14 12.6 46.2 0.042 14.3 4.1 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type RhoGAP PF00620.27 KFP22763.1 - 3.1e-50 169.9 1.3 4.1e-50 169.6 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain SH3-WW_linker PF16618.5 KFP22763.1 - 1.3e-43 149.8 13.0 1.3e-43 149.8 13.0 3.4 3 1 0 3 3 3 1 Linker region between SH3 and WW domains on ARHGAP12 PH PF00169.29 KFP22763.1 - 5.3e-09 36.5 0.7 2.8e-08 34.2 0.7 2.4 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KFP22763.1 - 4.6e-08 32.8 0.2 1.1e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_9 PF15410.6 KFP22763.1 - 2.5e-07 31.1 2.1 1e-06 29.1 0.4 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_1 PF00018.28 KFP22763.1 - 8e-07 28.6 3.5 5.3e-06 26.0 0.9 2.5 2 0 0 2 2 2 1 SH3 domain WW PF00397.26 KFP22763.1 - 7.3e-05 22.8 25.4 0.0009 19.3 5.5 4.4 3 1 1 4 4 4 2 WW domain SH3_10 PF17902.1 KFP22763.1 - 0.023 14.8 0.7 0.086 12.9 0.1 2.3 2 0 0 2 2 2 0 SH3 domain SH3_3 PF08239.11 KFP22763.1 - 0.19 12.0 1.9 1.6 9.1 0.4 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain Glyco_hyd_101C PF17451.2 KFP22763.1 - 0.97 9.7 14.5 0.68 10.2 0.6 4.0 5 0 0 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain Kinesin PF00225.23 KFP22764.1 - 4.6e-111 371.0 2.7 4.6e-111 371.0 2.7 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KFP22764.1 - 1.2e-23 83.7 0.2 1.2e-23 83.7 0.2 3.5 4 1 0 4 4 4 1 Microtubule binding APG6_N PF17675.1 KFP22764.1 - 0.014 15.9 24.6 0.014 15.9 24.6 5.7 2 2 3 5 5 5 0 Apg6 coiled-coil region DUF4226 PF10774.9 KFP22764.1 - 0.028 14.7 1.3 0.028 14.7 1.3 5.6 3 1 2 6 6 6 0 Domain of unknown function (DUF4226) Cation_ATPase PF13246.6 KFP22764.1 - 4.4 7.5 7.4 4.9 7.3 0.5 3.9 3 1 0 3 3 3 0 Cation transport ATPase (P-type) E_Pc_C PF06752.12 KFP22765.1 - 6.3e-98 327.5 43.7 6.3e-98 327.5 43.7 2.4 2 1 0 2 2 2 1 Enhancer of Polycomb C-terminus EPL1 PF10513.9 KFP22765.1 - 4.5e-06 27.1 0.7 4.5e-06 27.1 0.7 3.6 4 1 0 4 4 4 1 Enhancer of polycomb-like CAF1A PF12253.8 KFP22765.1 - 0.13 12.5 0.7 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A PKK PF12474.8 KFP22765.1 - 0.13 12.4 16.2 0.084 13.0 4.1 2.8 2 0 0 2 2 2 0 Polo kinase kinase CUB PF00431.20 KFP22769.1 - 4.4e-57 191.2 0.0 2.7e-27 95.3 0.0 2.7 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.25 KFP22769.1 - 2.5e-54 182.8 2.2 1.6e-28 99.4 0.1 2.7 3 0 0 3 3 3 2 F5/8 type C domain DUF3481 PF11980.8 KFP22769.1 - 1e-47 159.7 0.2 1.9e-47 158.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein MAM PF00629.23 KFP22769.1 - 1.7e-39 135.3 1.2 1.7e-39 135.3 1.2 1.7 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu PDZ PF00595.24 KFP22771.1 - 3.2e-37 126.7 4.8 2.4e-15 56.7 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KFP22771.1 - 5.7e-19 67.7 0.0 5.6e-07 29.3 0.1 3.6 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFP22771.1 - 6.8e-15 55.2 0.3 4.7e-06 26.8 0.1 3.8 3 0 0 3 3 3 3 PDZ domain RmlD_sub_bind PF04321.17 KFP22774.1 - 2.5e-85 286.1 0.0 2.9e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFP22774.1 - 2.8e-22 79.4 0.0 3.6e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFP22774.1 - 3.8e-10 39.4 0.1 2.1e-07 30.4 0.1 2.8 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFP22774.1 - 2.5e-09 37.0 0.0 1.1e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFP22774.1 - 5.8e-06 25.7 0.2 0.002 17.3 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFP22774.1 - 0.0026 16.8 0.1 0.018 14.1 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFP22774.1 - 0.019 14.4 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 KFP22774.1 - 0.03 14.2 0.0 2.8 7.8 0.0 2.5 2 1 0 2 2 2 0 KR domain HMMR_N PF15905.5 KFP22775.1 - 3e-95 319.5 63.4 3e-95 319.5 63.4 4.3 2 1 2 4 4 4 1 Hyaluronan mediated motility receptor N-terminal HMMR_C PF15908.5 KFP22775.1 - 3.5e-59 199.6 17.7 3.5e-59 199.6 17.7 6.2 2 1 3 6 6 6 1 Hyaluronan mediated motility receptor C-terminal ORF6C PF10552.9 KFP22775.1 - 0.011 15.8 5.0 0.011 15.8 5.0 7.5 3 2 3 7 7 7 0 ORF6C domain Cyclin_N PF00134.23 KFP22776.1 - 7e-22 77.5 0.2 1.8e-21 76.2 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFP22776.1 - 0.059 13.5 2.5 0.12 12.5 1.4 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain Neur_chan_memb PF02932.16 KFP22779.1 - 1.4e-39 136.5 9.7 8.9e-37 127.4 3.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP22779.1 - 2e-39 135.3 1.9 2.8e-39 134.8 1.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.23 KFP22782.1 - 6.9e-51 172.7 0.0 9.1e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP22782.1 - 2.2e-38 132.7 4.6 5.4e-31 108.5 4.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KFP22785.1 - 8.5e-44 149.6 0.2 1.1e-43 149.1 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP22785.1 - 1.4e-38 133.3 6.1 1.9e-34 119.8 3.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.23 KFP22785.1 - 0.028 14.2 0.4 0.051 13.3 0.4 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF4396 PF14342.6 KFP22785.1 - 0.13 12.6 8.2 0.069 13.5 4.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Neur_chan_LBD PF02931.23 KFP22786.1 - 1.2e-49 168.7 0.0 2.1e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KFP22786.1 - 1.1e-47 163.1 0.8 5.3e-47 160.9 0.8 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PhoLip_ATPase_C PF16212.5 KFP22789.1 - 4e-81 272.5 23.2 1e-80 271.1 23.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP22789.1 - 2.1e-21 75.4 2.7 7.3e-21 73.6 2.7 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP22789.1 - 4e-12 46.9 0.1 3.8e-06 27.3 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP22789.1 - 8.2e-09 35.4 0.0 4.2e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP22789.1 - 0.00028 20.5 0.0 0.00075 19.1 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP22789.1 - 0.0044 16.8 0.7 0.02 14.6 0.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Securin PF04856.13 KFP22790.1 - 1.9e-10 41.2 0.4 2.3e-10 40.9 0.4 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor Sterile PF03015.19 KFP22790.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Slu7 PF11708.8 KFP22791.1 - 2.3e-109 365.3 11.9 2.3e-109 365.3 11.9 2.9 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFP22791.1 - 0.026 14.2 0.3 0.053 13.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle C1q PF00386.21 KFP22792.1 - 1.5e-38 131.9 0.0 1.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP22792.1 - 1.2e-17 63.4 62.3 9.4e-10 38.1 34.8 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 KFP22792.1 - 0.0053 16.7 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 BclA C-terminal domain Lipocalin_7 PF14651.6 KFP22793.1 - 1.2e-62 209.5 1.4 1.4e-62 209.3 1.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF413 PF04219.12 KFP22793.1 - 0.046 13.8 0.1 0.072 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF PWWP PF00855.17 KFP22795.1 - 5.3e-12 46.0 0.0 5.3e-12 46.0 0.0 3.1 2 1 1 3 3 3 1 PWWP domain TPR_1 PF00515.28 KFP22796.1 - 2.2e-24 84.2 3.3 2.8e-07 30.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22796.1 - 5.5e-18 63.6 3.0 3.7e-05 23.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22796.1 - 4.8e-11 42.0 7.2 0.0018 18.3 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22796.1 - 2.1e-10 40.1 4.9 0.0022 17.6 0.1 3.4 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 KFP22796.1 - 3.3e-09 36.9 3.1 0.00025 21.3 1.3 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP22796.1 - 1.3e-08 35.2 1.7 1.9e-06 28.2 1.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22796.1 - 1.6e-07 31.5 1.9 0.0017 19.0 0.7 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22796.1 - 3.5e-07 30.3 2.3 2.3e-06 27.7 1.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFP22796.1 - 1.4e-05 24.5 3.4 0.0094 15.2 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22796.1 - 1.8e-05 25.3 0.9 0.0072 16.9 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFP22796.1 - 0.00017 22.0 1.0 0.011 16.3 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22796.1 - 0.00018 21.3 1.3 0.45 10.7 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22796.1 - 0.0014 18.8 4.8 0.0041 17.4 0.1 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFP22796.1 - 0.0092 16.1 0.5 0.81 9.8 0.5 2.9 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 KFP22796.1 - 0.022 14.5 6.8 0.056 13.1 1.2 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 KFP22796.1 - 0.027 14.5 2.0 0.89 9.7 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KFP22796.1 - 0.075 12.9 1.7 25 4.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3870 PF12986.7 KFP22796.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) NYD-SP28_assoc PF14775.6 KFP22796.1 - 1.4 9.1 5.5 5 7.3 1.8 2.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain PGA2 PF07543.12 KFP22796.1 - 3.6 7.6 11.0 0.29 11.1 1.2 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 7tm_1 PF00001.21 KFP22797.1 - 1.2e-80 270.6 7.4 1.6e-80 270.3 7.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22797.1 - 9.3e-16 58.0 4.4 2.1e-15 56.8 4.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22797.1 - 1.4e-05 24.9 10.7 1.4e-05 24.9 10.7 1.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KFP22797.1 - 1.7e-05 24.7 11.4 2e-05 24.5 4.7 2.7 3 0 0 3 3 3 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 KFP22797.1 - 0.00072 19.0 3.6 0.0024 17.3 3.6 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.6 KFP22797.1 - 0.12 12.6 0.1 6.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1980 PF09323.10 KFP22797.1 - 0.26 11.2 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TraL PF07178.11 KFP22797.1 - 3.3 8.2 7.0 4.9 7.7 0.2 3.2 3 0 0 3 3 3 0 TraL protein BRI3BP PF14965.6 KFP22797.1 - 3.7 7.0 13.1 0.095 12.2 1.2 3.3 2 2 1 3 3 3 0 Negative regulator of p53/TP53 IL12p40_C PF10420.9 KFP22798.1 - 9.9e-24 83.7 1.9 2.2e-23 82.6 1.2 2.0 2 0 0 2 2 2 1 Cytokine interleukin-12p40 C-terminus Ig_5 PF16681.5 KFP22798.1 - 2.7e-05 24.5 0.3 0.00039 20.8 0.0 2.6 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_3 PF13927.6 KFP22798.1 - 0.00028 21.4 6.3 0.0022 18.6 0.2 3.2 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KFP22798.1 - 0.00063 20.0 2.4 0.016 15.5 0.0 3.2 2 1 1 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFP22798.1 - 0.0013 19.0 0.1 0.079 13.2 0.1 2.6 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain ig PF00047.25 KFP22798.1 - 0.019 15.1 0.2 0.019 15.1 0.2 4.1 4 2 0 4 4 4 0 Immunoglobulin domain LPD29 PF18847.1 KFP22798.1 - 0.083 13.8 0.1 0.24 12.4 0.1 1.8 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 F-box PF00646.33 KFP22799.1 - 0.00019 21.2 0.1 0.00058 19.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFP22799.1 - 0.0026 17.6 0.3 0.0064 16.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like 7tm_1 PF00001.21 KFP22800.1 - 7.9e-68 228.6 14.8 1.1e-67 228.2 14.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2304 PF10066.9 KFP22800.1 - 1.7 8.9 8.7 15 5.9 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Sulfate_transp PF00916.20 KFP22801.1 - 1.1e-131 439.1 18.7 2.2e-131 438.1 18.8 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KFP22801.1 - 1.6e-28 98.7 0.0 2.8e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain RhoGEF PF00621.20 KFP22802.1 - 5.9e-35 121.2 1.0 1.2e-34 120.1 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 KFP22802.1 - 2.4e-13 49.6 0.0 3.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain BAR PF03114.18 KFP22802.1 - 1.3e-11 44.6 2.7 8.6e-05 22.3 0.6 3.0 1 1 2 3 3 3 2 BAR domain SH3_9 PF14604.6 KFP22802.1 - 2e-11 43.6 0.0 1.6e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFP22802.1 - 6.9e-08 32.0 0.0 2.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 KFP22802.1 - 5.5e-05 23.4 0.0 0.00042 20.5 0.0 2.3 3 0 0 3 3 3 1 Bacterial SH3 domain UvrB PF12344.8 KFP22802.1 - 2.5 8.0 4.0 0.93 9.4 0.8 1.9 2 0 0 2 2 2 0 Ultra-violet resistance protein B Pkinase PF00069.25 KFP22803.1 - 2e-27 96.2 0.0 2.5e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22803.1 - 4.9e-15 55.5 0.0 5.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFP22803.1 - 1.9e-10 40.1 0.0 1.9e-10 40.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KFP22803.1 - 0.021 13.8 0.1 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC1 PF03109.16 KFP22803.1 - 0.095 12.9 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 KFP22803.1 - 0.096 12.0 1.0 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP22803.1 - 0.2 11.5 0.2 1.1 9.1 0.2 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family IL17 PF06083.11 KFP22804.1 - 6.4e-30 103.5 1.5 1e-29 102.8 1.5 1.3 1 0 0 1 1 1 1 Interleukin-17 MRI PF15325.6 KFP22804.1 - 0.1 13.7 0.0 0.17 13.0 0.0 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Prenylcys_lyase PF07156.14 KFP22805.1 - 1.6e-90 303.9 0.0 1.9e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase GrpE PF01025.19 KFP22806.1 - 2.4e-42 144.4 0.0 2.9e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 GrpE DUF2408 PF10303.9 KFP22806.1 - 0.0076 16.8 0.2 0.011 16.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) CLZ PF16526.5 KFP22806.1 - 0.03 14.7 0.7 0.42 11.0 0.1 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_I PF06008.14 KFP22806.1 - 0.084 12.6 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF4525 PF15027.6 KFP22806.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) AbLIM_anchor PF16182.5 KFP22807.1 - 6.5e-87 292.8 25.1 5.7e-73 246.9 4.2 3.1 1 1 2 3 3 3 3 Putative adherens-junction anchoring region of AbLIM LIM PF00412.22 KFP22807.1 - 5e-34 116.3 46.0 1.5e-14 54.0 3.9 5.0 5 0 0 5 5 5 3 LIM domain VHP PF02209.19 KFP22807.1 - 5.3e-16 58.4 0.3 2.8e-15 56.1 0.8 2.0 2 0 0 2 2 2 1 Villin headpiece domain TPR_12 PF13424.6 KFP22809.1 - 9.3e-12 45.1 41.0 1.4e-06 28.5 3.0 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat SH3_2 PF07653.17 KFP22809.1 - 2.1e-08 33.7 0.1 0.0012 18.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KFP22809.1 - 8.8e-08 31.9 0.3 0.0031 17.3 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KFP22809.1 - 1.7e-07 30.7 0.3 0.0012 18.4 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SNAP PF14938.6 KFP22809.1 - 3.4e-07 30.0 2.3 2.7e-06 27.0 0.7 2.9 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 KFP22809.1 - 0.00011 22.2 31.9 1.5 9.3 0.4 11.1 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22809.1 - 0.00012 21.7 32.3 0.0011 18.7 0.0 9.4 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22809.1 - 0.035 14.2 0.1 0.035 14.2 0.1 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat Yae1_N PF09811.9 KFP22810.1 - 5.7e-17 61.1 63.1 1.8e+04 -27.9 63.1 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal UBD PF16455.5 KFP22811.1 - 4.4e-39 132.9 0.0 6.1e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFP22811.1 - 1.7e-13 50.1 0.0 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFP22811.1 - 5.3e-05 23.0 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SH3_1 PF00018.28 KFP22813.1 - 1.5e-39 133.3 14.5 1.6e-13 50.0 0.3 4.5 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 KFP22813.1 - 1.6e-34 117.5 9.2 6.9e-13 48.2 0.1 4.7 5 0 0 5 5 5 4 Variant SH3 domain SH3_2 PF07653.17 KFP22813.1 - 4.1e-31 106.4 4.6 2.6e-09 36.6 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 KFP22813.1 - 9.5e-13 48.2 12.3 5.1e-05 23.5 0.3 4.4 4 0 0 4 4 4 4 Bacterial SH3 domain PX PF00787.24 KFP22813.1 - 2.1e-06 27.7 3.0 3.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 PX domain Neuralized PF07177.12 KFP22814.1 - 1.1e-88 294.8 0.0 1.5e-44 151.6 0.0 2.6 3 0 0 3 3 3 2 Neuralized zf-C3HC4_3 PF13920.6 KFP22814.1 - 1e-12 47.7 13.9 2.5e-12 46.5 13.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP22814.1 - 5.8e-05 22.9 13.3 0.00015 21.6 13.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFP22814.1 - 0.081 12.9 14.9 0.2 11.6 14.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFP22814.1 - 0.39 10.6 16.6 0.85 9.5 16.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COPIIcoated_ERV PF07970.12 KFP22816.1 - 1.6e-36 126.2 0.1 2.7e-36 125.5 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFP22816.1 - 7.9e-36 122.3 0.0 7.9e-36 122.3 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ribosomal_L26 PF16906.5 KFP22817.1 - 9.1e-44 147.8 5.8 1.2e-43 147.4 5.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFP22817.1 - 6.9e-08 32.2 5.9 2.2e-07 30.6 5.9 2.0 1 1 0 1 1 1 1 KOW motif BLYB PF05289.11 KFP22817.1 - 0.033 14.4 1.9 0.055 13.7 1.9 1.4 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein bZIP_1 PF00170.21 KFP22818.1 - 0.0041 17.2 2.8 0.0041 17.2 2.8 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KFP22818.1 - 0.017 15.2 2.3 0.017 15.2 2.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper CDC45 PF02724.14 KFP22818.1 - 3.3 5.9 11.7 5 5.3 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Sec20 PF03908.13 KFP22819.1 - 1.1e-33 115.0 3.3 2e-33 114.2 3.3 1.4 1 0 0 1 1 1 1 Sec20 DUF2777 PF10949.8 KFP22819.1 - 0.0028 17.4 1.6 0.0039 16.9 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) DUF3490 PF11995.8 KFP22819.1 - 7.3 6.4 9.6 3.9 7.3 6.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3490) Homeodomain PF00046.29 KFP22820.1 - 3.4e-20 71.6 4.3 6.8e-20 70.7 4.3 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 KFP22820.1 - 0.067 12.7 0.5 0.18 11.3 0.3 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Stanniocalcin PF03298.13 KFP22821.1 - 8.3e-84 279.9 13.9 1e-83 279.6 13.9 1.1 1 0 0 1 1 1 1 Stanniocalcin family COMPASS-Shg1 PF05205.12 KFP22822.1 - 9.9e-14 51.9 0.0 1.2e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RRM_7 PF16367.5 KFP22823.1 - 8.1e-38 128.4 0.0 4.4e-36 122.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KFP22823.1 - 1.7e-20 73.0 5.1 4.4e-20 71.7 5.1 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KFP22823.1 - 2.3e-12 46.6 0.0 2.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KFP22823.1 - 0.031 14.1 0.4 0.082 12.7 0.4 1.7 1 0 0 1 1 1 0 U1 zinc finger Calcyon PF06387.11 KFP22824.1 - 2.8e-88 294.7 0.0 3.2e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) NB PF04159.13 KFP22824.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 NB glycoprotein 7tm_1 PF00001.21 KFP22827.1 - 9.6e-72 241.5 19.6 1.2e-71 241.1 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22827.1 - 3e-09 36.7 18.0 5.3e-09 35.8 18.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KFP22827.1 - 2.3e-07 30.7 15.5 2.3e-07 30.7 15.5 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF621 PF04789.15 KFP22827.1 - 0.096 11.8 18.1 0.046 12.9 14.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF621) Mtc PF03820.17 KFP22828.1 - 6.3e-124 413.1 0.6 7.3e-124 412.9 0.6 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ras PF00071.22 KFP22829.1 - 1.3e-62 210.2 0.1 1.5e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP22829.1 - 1.3e-34 119.0 0.1 2.4e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP22829.1 - 2.5e-11 43.4 0.1 2.9e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFP22829.1 - 3.5e-07 30.3 0.0 5.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFP22829.1 - 3.6e-05 24.1 0.1 0.00041 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFP22829.1 - 5e-05 23.3 0.1 0.023 14.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFP22829.1 - 0.00015 21.4 0.1 0.00034 20.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFP22829.1 - 0.0073 16.7 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KFP22829.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KFP22829.1 - 0.03 13.9 0.1 0.11 12.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KFP22829.1 - 0.034 14.7 0.1 0.046 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KFP22829.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KFP22829.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KFP22829.1 - 0.078 12.4 0.3 0.23 10.8 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein FAD-SLDH PF12318.8 KFP22829.1 - 0.084 12.9 0.2 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PduV-EutP PF10662.9 KFP22829.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFP22829.1 - 0.16 11.8 0.8 0.3 10.9 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DENN PF02141.21 KFP22830.1 - 3e-59 200.1 4.2 3e-59 200.1 4.2 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KFP22830.1 - 6.4e-17 62.1 0.1 2.9e-16 60.0 0.1 2.3 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFP22830.1 - 4.6e-14 52.1 5.3 4.6e-14 52.1 5.3 2.3 3 0 0 3 3 3 1 dDENN domain PPR_2 PF13041.6 KFP22830.1 - 6.7e-07 29.4 0.0 2e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 PPR repeat family PPR_3 PF13812.6 KFP22830.1 - 0.00017 21.6 0.4 0.001 19.1 0.1 2.4 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KFP22830.1 - 0.00032 20.2 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFP22830.1 - 0.0081 16.4 0.0 0.054 13.8 0.0 2.4 2 0 0 2 2 2 1 PPR repeat Papo_T_antigen PF02380.15 KFP22830.1 - 0.24 11.6 4.9 0.16 12.1 1.0 2.5 2 0 0 2 2 2 0 T-antigen specific domain Na_Ca_ex PF01699.24 KFP22831.1 - 1.4e-58 197.1 47.0 3e-31 108.4 24.1 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PBP1_TM PF14812.6 KFP22831.1 - 0.045 14.1 1.3 0.17 12.3 1.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GREB1 PF15782.5 KFP22831.1 - 0.047 10.8 1.6 0.058 10.5 1.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NOA36 PF06524.12 KFP22831.1 - 4 6.7 6.6 5.6 6.2 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KFP22831.1 - 6.7 6.2 12.9 10 5.6 12.9 1.2 1 0 0 1 1 1 0 PPP4R2 VWA_2 PF13519.6 KFP22832.1 - 4.7e-15 56.1 0.0 2.1e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain PTPLA PF04387.14 KFP22833.1 - 7.7e-52 175.3 4.5 1.2e-51 174.8 4.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ELO PF01151.18 KFP22833.1 - 0.014 15.0 12.3 0.023 14.3 12.3 1.3 1 1 0 1 1 1 0 GNS1/SUR4 family DPPIV_N PF00930.21 KFP22834.1 - 8.4e-99 330.7 0.0 1.1e-98 330.3 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFP22834.1 - 1.1e-60 204.7 0.1 2.1e-60 203.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFP22834.1 - 4.7e-08 32.9 0.0 8.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFP22834.1 - 0.00043 20.9 0.0 0.00094 19.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFP22834.1 - 0.0062 16.2 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFP22834.1 - 0.038 13.8 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KFP22834.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold fn3 PF00041.21 KFP22835.1 - 8.2e-63 208.8 13.2 9.9e-16 57.9 1.3 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.16 KFP22835.1 - 5e-51 170.7 0.4 2.2e-18 66.1 0.0 5.9 5 1 0 5 5 5 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP22835.1 - 9.8e-51 170.3 3.2 9.2e-16 58.2 0.1 6.0 5 1 1 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KFP22835.1 - 2.9e-34 117.2 0.4 5.2e-10 39.5 0.0 5.0 4 1 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 KFP22835.1 - 5.4e-29 100.2 0.3 6.1e-09 35.9 0.0 6.1 4 1 1 5 5 5 4 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KFP22835.1 - 3.5e-20 72.4 9.2 0.00078 20.0 0.0 6.2 6 0 0 6 6 5 4 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 KFP22835.1 - 4.8e-16 58.9 2.7 0.021 15.0 0.0 7.4 5 3 1 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP22835.1 - 1.7e-09 37.6 0.3 0.075 13.1 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KFP22835.1 - 6.6e-08 32.0 0.0 0.14 11.7 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 KFP22835.1 - 2.1e-06 28.0 0.0 0.32 11.4 0.0 4.8 4 1 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Interfer-bind PF09294.10 KFP22835.1 - 0.002 18.4 0.6 1.5 9.1 0.2 3.8 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Ig_4 PF16680.5 KFP22835.1 - 0.0021 18.3 0.0 4.2 7.7 0.0 4.1 4 0 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Ig_C17orf99 PF17736.1 KFP22835.1 - 0.0075 16.3 0.5 0.52 10.4 0.0 3.3 3 0 0 3 3 3 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP22835.1 - 0.014 15.4 0.0 1.8 8.7 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain SusE PF14292.6 KFP22835.1 - 0.048 13.9 1.2 0.59 10.4 0.1 3.0 3 0 0 3 3 3 0 SusE outer membrane protein Cadherin PF00028.17 KFP22835.1 - 0.18 12.2 0.3 3.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Cadherin domain Adeno_E3_CR2 PF02439.15 KFP22835.1 - 0.31 10.8 5.4 0.88 9.4 5.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tissue_fac PF01108.17 KFP22835.1 - 1 9.3 3.2 7.1 6.5 0.0 3.2 3 0 0 3 3 3 0 Tissue factor Xpo1 PF08389.12 KFP22836.1 - 7.1e-25 87.8 0.5 1.1e-24 87.2 0.5 1.3 1 0 0 1 1 1 1 Exportin 1-like protein PAP2 PF01569.21 KFP22837.1 - 9.9e-21 73.9 1.1 1.8e-20 73.1 1.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily Ribosomal_L50 PF10501.9 KFP22838.1 - 1.2e-10 41.5 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S Glycolytic PF00274.19 KFP22839.1 - 2.4e-146 487.0 2.3 3.4e-97 325.3 0.0 2.0 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-I zf-C3HC4_3 PF13920.6 KFP22841.1 - 1.3e-06 28.2 11.6 2.2e-06 27.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP22841.1 - 7.2e-05 22.6 14.6 0.00013 21.7 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP22841.1 - 0.00022 21.0 14.6 0.0004 20.2 14.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP22841.1 - 0.00033 20.5 13.6 0.0016 18.4 14.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFP22841.1 - 0.0016 18.7 13.3 0.0028 17.9 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFP22841.1 - 0.0081 16.0 9.2 0.015 15.1 9.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFP22841.1 - 0.012 15.9 8.0 0.028 14.7 8.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFP22841.1 - 0.019 15.0 10.4 0.039 14.0 10.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFP22841.1 - 0.59 10.2 4.8 1.1 9.4 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFP22841.1 - 1.7 8.9 10.0 4.8 7.4 10.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Lig_chan PF00060.26 KFP22842.1 - 1.1e-29 103.2 0.2 4.1e-29 101.3 0.0 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KFP22842.1 - 5.9e-27 94.1 0.0 4.9e-26 91.2 0.0 2.3 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KFP22842.1 - 5.2e-20 71.8 0.0 8.7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 KFP22842.1 - 2.2e-07 30.3 0.3 0.0042 16.2 0.2 2.2 1 1 1 2 2 2 2 Receptor family ligand binding region JIP_LZII PF16471.5 KFP22842.1 - 0.1 12.8 3.0 0.29 11.3 2.9 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II IQ PF00612.27 KFP22843.1 - 0.017 14.8 1.3 0.084 12.7 1.3 2.3 1 0 0 1 1 1 0 IQ calmodulin-binding motif UL42 PF17638.2 KFP22844.1 - 8.9 6.3 7.7 26 4.8 0.2 2.3 2 0 0 2 2 2 0 HCMV UL42 MFS_1 PF07690.16 KFP22846.1 - 5e-15 55.3 25.5 5e-15 55.3 25.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UMP1 PF05348.11 KFP22847.1 - 3.4e-38 130.5 0.0 4.2e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase_Tyr PF07714.17 KFP22848.1 - 7.7e-107 356.4 0.0 1.1e-106 355.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP22848.1 - 4.5e-45 154.1 0.0 6.8e-31 107.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP22848.1 - 1.4e-26 92.8 0.7 4.5e-14 52.8 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KFP22848.1 - 6.5e-26 90.2 0.0 4.3e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP22848.1 - 1.5e-21 76.5 0.1 3.8e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP22848.1 - 6.6e-18 64.7 0.1 2e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain VEGFR-2_TMD PF17988.1 KFP22848.1 - 1e-17 63.3 0.4 1.8e-17 62.4 0.4 1.4 1 0 0 1 1 1 1 VEGFR-2 Transmembrane domain V-set PF07686.17 KFP22848.1 - 1.3e-09 38.2 1.3 0.0009 19.4 0.2 4.0 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_4 PF16680.5 KFP22848.1 - 1.7e-05 25.0 0.1 0.022 15.0 0.0 2.9 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KFP22848.1 - 0.0003 21.1 0.1 0.72 10.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KFP22848.1 - 0.0027 17.2 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Haspin_kinase PF12330.8 KFP22848.1 - 0.0094 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Izumo-Ig PF16706.5 KFP22848.1 - 0.013 15.5 0.1 7.8 6.6 0.0 3.0 2 1 0 2 2 2 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KFP22848.1 - 0.032 13.0 0.0 0.15 10.8 0.0 1.9 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pan3_PK PF18101.1 KFP22849.1 - 1.4e-62 209.7 0.0 2.3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFP22849.1 - 0.0015 18.0 0.0 0.0046 16.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22850.1 - 7.9e-102 340.0 0.0 1.1e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP22850.1 - 3e-44 151.4 0.0 1e-27 97.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KFP22850.1 - 2.3e-09 37.7 7.4 0.49 11.0 0.0 5.8 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 KFP22850.1 - 2e-08 34.3 0.1 0.00012 22.1 0.0 3.9 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 KFP22850.1 - 3.2e-07 30.3 4.5 0.028 14.5 0.0 5.4 6 0 0 6 6 6 2 Immunoglobulin I-set domain Haspin_kinase PF12330.8 KFP22850.1 - 0.001 18.1 0.3 0.0043 16.1 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Ig_2 PF13895.6 KFP22850.1 - 0.0055 17.0 5.3 0.11 12.8 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin domain APH PF01636.23 KFP22850.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WDCP PF15390.6 KFP22851.1 - 0.74 8.1 4.8 0.66 8.3 4.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family LCD1 PF09798.9 KFP22851.1 - 2.5 6.5 5.6 2.8 6.3 5.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PDZ PF00595.24 KFP22852.1 - 2.9e-65 216.6 1.8 9.1e-16 58.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP22852.1 - 1.8e-30 104.6 0.9 1.5e-07 31.1 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP22852.1 - 1.8e-17 63.4 0.1 7.8e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 PDZ domain zf-C3HC4_2 PF13923.6 KFP22852.1 - 2.7e-08 33.5 8.4 2.7e-08 33.5 8.4 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP22852.1 - 4.2e-08 32.9 6.7 4.2e-08 32.9 6.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP22852.1 - 6.2e-07 29.7 6.1 6.2e-07 29.7 6.1 3.5 5 0 0 5 5 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP22852.1 - 8.2e-07 28.9 7.9 8.2e-07 28.9 7.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFP22852.1 - 2e-06 27.5 3.1 2e-06 27.5 3.1 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFP22852.1 - 8.4e-06 25.6 5.4 8.4e-06 25.6 5.4 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFP22852.1 - 9.2e-05 22.5 7.6 9.2e-05 22.5 7.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFP22852.1 - 0.0021 18.3 4.3 0.0021 18.3 4.3 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFP22852.1 - 0.15 11.9 9.7 0.061 13.2 5.0 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KFP22852.1 - 0.16 11.9 2.2 0.38 10.6 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit eIF3g PF12353.8 KFP22852.1 - 0.6 10.5 5.6 3.4 8.1 0.6 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DZR PF12773.7 KFP22852.1 - 0.65 10.1 10.3 1.3 9.1 5.9 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_11 PF17123.5 KFP22852.1 - 1.6 8.6 7.9 1.1 9.0 4.6 2.7 2 1 0 2 2 2 0 RING-like zinc finger IF3_N PF05198.16 KFP22853.1 - 8.3e-17 61.2 0.1 5.1e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 KFP22853.1 - 3.7e-09 36.4 0.6 1.2e-08 34.8 0.6 2.0 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Rgp1 PF08737.10 KFP22853.1 - 0.0034 16.6 2.0 0.0043 16.3 2.0 1.1 1 0 0 1 1 1 1 Rgp1 DUF4974 PF16344.5 KFP22853.1 - 0.026 14.5 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) HTH_33 PF13592.6 KFP22853.1 - 0.031 13.9 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix zf-C2H2 PF00096.26 KFP22854.1 - 1e-32 110.7 62.2 1.1e-05 25.5 0.7 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFP22854.1 - 4.7e-15 55.2 65.5 5.1e-05 23.5 0.7 9.4 8 1 1 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP22854.1 - 2.3e-14 52.8 54.8 0.0039 17.9 0.9 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KFP22854.1 - 0.00044 20.5 25.2 0.043 14.1 6.6 4.2 1 1 5 6 6 6 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFP22854.1 - 0.0016 18.7 26.1 0.89 9.9 0.0 6.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KFP22854.1 - 0.0095 15.7 1.1 0.0095 15.7 1.1 8.0 10 0 0 10 10 9 2 C2H2-type zinc-finger domain CHORD PF04968.12 KFP22854.1 - 0.046 14.4 41.7 1.9 9.3 0.5 6.8 2 2 5 7 7 7 0 CHORD BHD_1 PF10403.9 KFP22854.1 - 0.048 13.5 1.0 6.6 6.7 0.0 3.3 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 zf_Hakai PF18408.1 KFP22854.1 - 0.067 12.9 0.3 0.067 12.9 0.3 5.8 7 0 0 7 7 7 0 C2H2 Hakai zinc finger domain zf_C2H2_ZHX PF18387.1 KFP22854.1 - 0.069 12.8 0.3 0.069 12.8 0.3 4.2 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KFP22854.1 - 0.075 13.5 23.2 13 6.3 0.0 7.0 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFP22854.1 - 0.24 11.7 24.0 0.28 11.5 2.6 4.9 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KFP22854.1 - 0.42 11.3 31.3 0.75 10.5 0.0 6.6 2 1 5 7 7 7 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KFP22854.1 - 0.77 9.6 17.8 0.35 10.7 0.5 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type UCH PF00443.29 KFP22855.1 - 4.7e-61 206.5 1.9 5.5e-61 206.3 1.9 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP22855.1 - 2.4e-31 109.5 3.0 3.3e-31 109.1 3.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFP22855.1 - 0.0022 17.5 9.9 0.0045 16.5 7.0 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase CEBP_ZZ PF16366.5 KFP22855.1 - 0.59 10.4 6.5 0.51 10.6 1.7 2.4 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain 7tm_1 PF00001.21 KFP22856.1 - 1.5e-35 122.8 20.8 1.8e-35 122.6 20.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP22856.1 - 9.5e-06 25.2 11.9 9.5e-06 25.2 11.9 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP22856.1 - 3.6e-05 23.6 19.0 0.00017 21.4 19.0 2.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KFP22856.1 - 0.91 9.1 25.5 0.05 13.2 16.9 2.5 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx WH2 PF02205.20 KFP22857.1 - 3.9e-07 29.7 0.1 6.7e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 WH2 motif zf-C2H2_4 PF13894.6 KFP22858.1 - 7.9e-10 38.7 37.5 0.017 15.9 3.5 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP22858.1 - 4.3e-08 33.2 30.2 0.0014 19.0 3.5 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-BED PF02892.15 KFP22858.1 - 2.6e-06 27.3 27.8 0.038 14.0 4.9 5.5 4 1 1 5 5 5 4 BED zinc finger IBR PF01485.21 KFP22858.1 - 7.1e-06 26.2 17.8 0.067 13.4 1.8 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain CpXC PF14353.6 KFP22858.1 - 1.4e-05 25.1 11.7 0.0029 17.6 0.1 3.8 2 1 1 3 3 3 2 CpXC protein zf-C2H2_jaz PF12171.8 KFP22858.1 - 1.8e-05 24.9 17.4 0.0015 18.8 1.2 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 KFP22858.1 - 0.00027 20.8 3.1 0.077 12.9 0.1 3.3 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_aberr PF17017.5 KFP22858.1 - 0.014 15.6 20.6 0.61 10.2 0.5 4.6 3 2 1 4 4 4 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 KFP22858.1 - 0.027 14.8 24.6 0.33 11.3 0.1 4.9 2 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Agenet PF05641.12 KFP22858.1 - 0.099 13.1 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Agenet domain zf-C2HE PF16278.5 KFP22858.1 - 0.1 13.1 25.0 2.3 8.8 2.1 6.1 5 2 1 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KFP22858.1 - 0.3 11.8 16.0 0.53 11.0 0.3 4.1 4 1 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_12 PF18658.1 KFP22858.1 - 1.9 8.1 12.2 9.8 5.8 0.0 4.1 3 1 1 4 4 4 0 Zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KFP22858.1 - 6.3 7.0 19.3 10 6.4 0.9 5.0 5 0 0 5 5 5 0 Zinc ribbon domain zf-met PF12874.7 KFP22858.1 - 9.5 6.8 20.7 0.47 10.9 0.3 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zinc_ribbon_2 PF13240.6 KFP22858.1 - 9.6 6.1 14.4 7 6.5 0.7 3.9 4 0 0 4 4 4 0 zinc-ribbon domain fn3 PF00041.21 KFP22859.1 - 3.1e-10 40.2 1.0 4.7e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III domain DUF4808 PF16066.5 KFP22859.1 - 0.00018 22.0 0.0 0.00035 21.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) Pur_ac_phosph_N PF16656.5 KFP22859.1 - 0.0038 17.8 0.2 0.012 16.2 0.2 1.9 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.5 KFP22859.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function PID PF00640.23 KFP22860.1 - 1.5e-19 70.4 0.2 1.9e-19 70.1 0.2 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.6 KFP22860.1 - 1.6e-13 50.9 0.1 2e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP22860.1 - 1.6e-10 41.3 0.1 2e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain ATP1G1_PLM_MAT8 PF02038.16 KFP22861.1 - 2e-26 91.2 0.1 2.2e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family HU-CCDC81_euk_2 PF18289.1 KFP22861.1 - 0.082 13.1 0.1 0.097 12.8 0.1 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 DUF2367 PF10164.9 KFP22861.1 - 0.11 13.0 0.3 0.13 12.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Syndecan PF01034.20 KFP22862.1 - 0.0006 19.7 0.1 0.00087 19.2 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.11 KFP22862.1 - 0.0027 17.7 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Protocadherin Spore_SspJ PF09575.10 KFP22862.1 - 0.016 15.6 0.8 0.023 15.0 0.8 1.2 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) FAM163 PF15069.6 KFP22862.1 - 0.026 15.0 0.0 0.028 14.9 0.0 1.1 1 0 0 1 1 1 0 FAM163 family EphA2_TM PF14575.6 KFP22862.1 - 0.027 15.3 0.0 0.033 15.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 KFP22862.1 - 0.028 14.6 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FTCD_C PF04961.12 KFP22862.1 - 0.046 13.5 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Chordopox_A13L PF05961.11 KFP22862.1 - 0.066 13.5 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Baculo_11_kDa PF06143.11 KFP22862.1 - 0.087 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF202 PF02656.15 KFP22862.1 - 0.1 13.0 0.2 0.13 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF4692 PF15763.5 KFP22862.1 - 0.14 12.6 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) ODV-E18 PF10717.9 KFP22862.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Amnionless PF14828.6 KFP22862.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF4381 PF14316.6 KFP22862.1 - 0.21 11.8 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adeno_E3_CR2 PF02439.15 KFP22862.1 - 0.56 10.0 6.4 0.9 9.3 6.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BAR PF03114.18 KFP22863.1 - 3.4e-43 148.0 9.4 4.4e-43 147.6 9.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFP22863.1 - 5.4e-12 45.4 0.2 2.6e-11 43.2 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP22863.1 - 3.7e-07 29.7 0.2 1e-06 28.2 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP22863.1 - 4.6e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KFP22863.1 - 0.0016 18.2 8.7 0.0041 16.9 8.4 1.8 1 1 1 2 2 2 1 BAR domain of APPL family Jnk-SapK_ap_N PF09744.9 KFP22863.1 - 0.017 15.4 1.5 0.017 15.4 1.5 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KFP22863.1 - 0.035 14.4 0.7 0.035 14.4 0.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CEP209_CC5 PF16574.5 KFP22863.1 - 0.055 13.6 0.8 0.055 13.6 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF3104 PF11302.8 KFP22863.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) BLOC1_2 PF10046.9 KFP22863.1 - 0.7 10.2 9.6 0.37 11.1 1.8 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arfaptin PF06456.13 KFP22863.1 - 1.1 8.8 7.7 2.7 7.5 7.7 1.7 1 1 0 1 1 1 0 Arfaptin-like domain PTS_IIA PF02255.16 KFP22863.1 - 1.9 8.6 6.8 6.9 6.8 1.9 2.7 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit p450 PF00067.22 KFP22864.1 - 1.1e-100 337.6 0.0 1.2e-100 337.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Importin_rep_6 PF18829.1 KFP22864.1 - 0.044 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Importin repeat 6 ERCC3_RAD25_C PF16203.5 KFP22865.1 - 1.8e-124 413.9 2.0 3.1e-124 413.1 2.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFP22865.1 - 9.1e-38 129.3 0.0 2.8e-37 127.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP22865.1 - 4.5e-16 59.3 0.0 1.4e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFP22865.1 - 1.6e-09 38.1 0.1 4.3e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFP22865.1 - 0.0013 17.5 0.0 0.0023 16.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2605 PF10792.9 KFP22865.1 - 0.047 13.6 0.3 0.16 11.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Pkinase PF00069.25 KFP22866.1 - 5.4e-66 222.6 0.0 6.8e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22866.1 - 3.4e-39 134.7 0.0 4.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 KFP22866.1 - 1.5e-12 47.3 0.2 3e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KFP22866.1 - 5.7e-06 25.9 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KFP22866.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KFP22866.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short_C2 PF13561.6 KFP22867.1 - 2.3e-46 158.3 0.2 2.6e-46 158.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFP22867.1 - 1.4e-37 129.1 0.3 1.7e-37 128.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase CABS1 PF15367.6 KFP22867.1 - 0.031 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 RINGv PF12906.7 KFP22869.1 - 5.3e-07 29.7 10.8 1.1e-06 28.6 10.8 1.6 1 0 0 1 1 1 1 RING-variant domain HARP PF07443.13 KFP22870.1 - 4.4e-53 176.7 0.4 1.6e-25 88.5 0.1 2.6 2 0 0 2 2 2 2 HepA-related protein (HARP) SNF2_N PF00176.23 KFP22870.1 - 9.5e-26 90.3 0.0 1.5e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFP22870.1 - 6.4e-15 55.5 0.0 2.7e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFP22870.1 - 1.9e-06 28.0 0.0 0.00021 21.4 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFP22870.1 - 1.4e-05 24.5 0.2 0.0002 20.6 0.1 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KFP22870.1 - 0.051 13.6 0.1 0.5 10.3 0.0 2.4 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 KFP22870.1 - 0.084 13.1 0.0 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Retro_M PF02813.14 KFP22870.1 - 0.11 12.9 0.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Retroviral M domain Ribosomal_L37ae PF01780.19 KFP22871.1 - 3.9e-47 158.2 11.2 4.4e-47 158.1 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KFP22871.1 - 0.0047 17.0 4.8 0.0073 16.4 4.2 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Elf1 PF05129.13 KFP22871.1 - 0.011 15.8 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Rsm1 PF08600.10 KFP22871.1 - 0.013 15.6 0.6 0.019 15.1 0.6 1.3 1 0 0 1 1 1 0 Rsm1-like Zn_Tnp_IS1595 PF12760.7 KFP22871.1 - 0.052 13.5 1.8 0.076 13.0 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.13 KFP22871.1 - 0.14 12.1 4.1 0.43 10.5 4.1 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger zf-BED PF02892.15 KFP22871.1 - 0.77 9.8 6.0 5.3 7.2 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger Thyroglobulin_1 PF00086.18 KFP22872.1 - 2.5e-18 65.5 0.8 4.7e-18 64.6 0.8 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Thyroglobulin_1 PF00086.18 KFP22873.1 - 3.3e-19 68.3 3.3 6.2e-19 67.4 3.3 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Pep_M12B_propep PF01562.19 KFP22874.1 - 2.2e-35 121.9 0.7 4.5e-35 120.9 0.7 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.14 KFP22874.1 - 2.2e-34 117.9 0.0 4.8e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.19 KFP22874.1 - 4.1e-31 106.9 81.2 2.5e-11 43.6 8.4 7.9 6 1 0 6 6 6 6 Thrombospondin type 1 domain Reprolysin PF01421.19 KFP22874.1 - 1.6e-28 100.0 0.1 3.1e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP22874.1 - 4.7e-20 71.9 8.3 4.7e-20 71.9 8.3 6.3 4 3 1 6 6 6 2 ADAM cysteine-rich domain PLAC PF08686.11 KFP22874.1 - 1.1e-10 42.1 8.8 1.1e-10 42.1 8.8 5.3 4 0 0 4 4 4 1 PLAC (protease and lacunin) domain Reprolysin_5 PF13688.6 KFP22874.1 - 1.1e-10 42.0 0.1 3.7e-10 40.3 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFP22874.1 - 3.2e-09 36.9 0.1 6.8e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KFP22874.1 - 1.6e-06 28.7 0.0 3.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP22874.1 - 0.0004 20.1 0.1 0.00088 19.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pribosyltran PF00156.27 KFP22875.1 - 0.003 17.1 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ADH_zinc_N_2 PF13602.6 KFP22876.1 - 1.2e-13 52.2 0.0 3.1e-13 50.9 0.0 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFP22876.1 - 5.1e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFP22876.1 - 4.6e-08 32.9 0.0 9.9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Lectin_C PF00059.21 KFP22877.1 - 8.1e-19 68.3 0.1 1.3e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.12 KFP22877.1 - 0.0039 16.5 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein GPS PF01825.21 KFP22877.1 - 0.13 12.8 0.7 0.34 11.5 0.7 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif adh_short PF00106.25 KFP22879.1 - 2e-27 95.9 0.0 5.8e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFP22879.1 - 7.9e-17 61.6 0.0 5.1e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFP22879.1 - 1.5e-09 38.1 0.1 2.1e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 KR domain WW PF00397.26 KFP22879.1 - 2.4e-08 33.9 5.7 3.5e-07 30.2 0.4 2.5 2 0 0 2 2 2 2 WW domain PerB PF06590.11 KFP22879.1 - 0.014 15.9 0.0 0.034 14.6 0.0 1.6 2 0 0 2 2 2 0 PerB protein Epimerase PF01370.21 KFP22879.1 - 0.043 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family bZIP_Maf PF03131.17 KFP22882.1 - 7.2e-22 77.7 10.8 1.4e-21 76.8 10.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Maf_N PF08383.11 KFP22882.1 - 1.9e-20 72.3 0.5 3e-20 71.7 0.5 1.3 1 0 0 1 1 1 1 Maf N-terminal region KASH_CCD PF14662.6 KFP22882.1 - 0.0014 18.5 3.3 0.0023 17.8 3.3 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 KFP22882.1 - 0.0032 17.9 10.0 0.016 15.7 5.3 2.2 1 1 1 2 2 2 1 Cell division protein ZapB bZIP_1 PF00170.21 KFP22882.1 - 0.0033 17.5 10.9 0.0059 16.7 10.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor APC_N_CC PF16689.5 KFP22882.1 - 0.0054 16.8 1.4 0.013 15.5 1.4 1.7 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain vATP-synt_E PF01991.18 KFP22882.1 - 0.019 14.4 3.7 0.026 13.9 3.7 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit GAS PF13851.6 KFP22882.1 - 0.028 13.8 5.1 0.041 13.2 5.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 KFP22882.1 - 0.031 14.4 8.7 0.057 13.5 8.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper CENP-Q PF13094.6 KFP22882.1 - 0.047 13.9 1.8 0.067 13.4 1.8 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit JIP_LZII PF16471.5 KFP22882.1 - 0.053 13.7 5.3 0.09 13.0 2.4 2.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF2353 PF09789.9 KFP22882.1 - 0.071 12.5 6.3 0.1 12.0 6.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) UBA PF00627.31 KFP22882.1 - 0.083 12.8 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain STAT_alpha PF01017.20 KFP22882.1 - 0.087 12.7 4.2 0.12 12.2 4.2 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain Seryl_tRNA_N PF02403.22 KFP22882.1 - 0.12 12.6 5.3 0.23 11.7 5.3 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1635 PF07795.11 KFP22882.1 - 0.15 11.9 1.9 0.29 11.0 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4407 PF14362.6 KFP22882.1 - 0.21 10.9 0.7 0.27 10.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 KFP22882.1 - 0.38 10.9 6.3 9.2 6.5 3.3 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KFP22882.1 - 0.44 10.4 5.5 0.29 10.9 1.9 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF573 PF04504.14 KFP22882.1 - 1.6 9.4 4.8 27 5.5 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF573 GIT_CC PF16559.5 KFP22882.1 - 2.6 8.0 6.3 2.1 8.3 1.2 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Robl_LC7 PF03259.17 KFP22885.1 - 8.2e-18 64.0 0.0 8.9e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain ECH_1 PF00378.20 KFP22887.1 - 3.8e-31 108.3 0.0 5.7e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 KFP22887.1 - 4.3e-16 58.6 1.8 9.5e-16 57.5 1.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 KFP22887.1 - 7.7e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Mtf2_C PF14061.6 KFP22887.1 - 0.048 13.8 0.8 0.097 12.9 0.8 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Cmc1 PF08583.10 KFP22888.1 - 4e-16 58.8 4.1 4.6e-16 58.6 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CENP-N PF05238.13 KFP22889.1 - 5.1e-71 240.2 3.8 1.1e-69 235.7 3.8 2.0 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Nudix_hydro PF18290.1 KFP22889.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Nudix hydrolase domain zf-C2H2_4 PF13894.6 KFP22890.1 - 0.07 14.0 12.8 2.3 9.3 0.5 4.4 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP22890.1 - 1.2 9.8 18.9 1.1 9.8 0.2 4.5 3 1 1 4 4 4 0 Zinc finger, C2H2 type GCV_H PF01597.19 KFP22891.1 - 1e-46 157.8 0.1 1.1e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RPE65 PF03055.15 KFP22892.1 - 1.4e-120 403.6 1.0 1.6e-120 403.4 1.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein LRR_4 PF12799.7 KFP22893.1 - 7e-06 26.3 10.2 0.0083 16.5 0.2 4.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFP22893.1 - 2.8e-05 23.8 2.2 0.12 12.1 0.2 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KFP22893.1 - 0.0051 16.8 1.1 5.1 7.4 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat PH PF00169.29 KFP22893.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 PH domain Microtub_bd PF16796.5 KFP22893.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding PI-PLC-X PF00388.19 KFP22894.1 - 1.3e-66 222.6 0.1 3.1e-66 221.4 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.24 KFP22894.1 - 6.9e-47 157.5 0.4 1.4e-24 86.0 0.1 2.9 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.19 KFP22894.1 - 1e-37 129.0 0.0 3.5e-37 127.2 0.0 2.0 2 0 0 2 2 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFP22894.1 - 7.4e-15 55.1 0.0 2.7e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 C2 domain SH3_1 PF00018.28 KFP22894.1 - 4.3e-13 48.7 0.1 1.3e-12 47.1 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFP22894.1 - 5e-11 42.3 0.1 2.1e-10 40.3 0.1 2.2 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KFP22894.1 - 4.4e-07 30.4 6.1 0.11 13.0 0.0 4.6 4 0 0 4 4 4 3 PH domain SH3_2 PF07653.17 KFP22894.1 - 1.2e-05 24.8 0.0 3.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH_12 PF16457.5 KFP22894.1 - 9.9e-05 22.9 0.4 0.0016 19.0 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain UCH_N PF16674.5 KFP22894.1 - 0.063 13.2 0.0 3.7 7.5 0.0 2.8 2 0 0 2 2 2 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 GDPD PF03009.17 KFP22894.1 - 0.067 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family 3Beta_HSD PF01073.19 KFP22895.1 - 2.7e-70 236.6 0.0 3.3e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFP22895.1 - 1.4e-25 90.2 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFP22895.1 - 5.2e-10 38.9 0.0 7.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFP22895.1 - 1.2e-08 34.8 0.0 6.8e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFP22895.1 - 2.2e-08 33.6 0.0 4.5e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFP22895.1 - 5.3e-07 29.1 0.4 2.5e-06 26.9 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFP22895.1 - 0.0031 17.4 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFP22896.1 - 1.2e-41 142.4 0.0 1.4e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFP22896.1 - 1.7e-28 99.8 0.0 2.1e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFP22896.1 - 5.1e-05 22.8 0.0 9.9e-05 21.8 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFP22896.1 - 9.6e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 KR domain LytR_C PF13399.6 KFP22896.1 - 0.25 12.4 0.5 6.1 7.9 0.1 2.3 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator DUF4462 PF14692.6 KFP22897.1 - 0.11 12.0 0.2 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Acetyltransf_2 PF00797.17 KFP22898.1 - 1.8e-91 306.2 0.0 2.1e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 KFP22899.1 - 1.4e-87 293.4 0.2 1.6e-87 293.3 0.2 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 KFP22900.1 - 8.6e-94 313.8 0.7 9.8e-94 313.6 0.7 1.0 1 0 0 1 1 1 1 N-acetyltransferase MPP6 PF10175.9 KFP22901.1 - 6.4e-35 120.5 3.7 6.4e-35 120.5 3.7 1.4 2 0 0 2 2 2 1 M-phase phosphoprotein 6 DUF5085 PF16895.5 KFP22901.1 - 0.0094 16.3 0.4 0.019 15.3 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5085) Ku_C PF03730.14 KFP22901.1 - 0.04 14.6 0.8 0.04 14.6 0.8 1.6 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF3864 PF12980.7 KFP22901.1 - 0.07 13.5 0.5 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Cadherin PF00028.17 KFP22902.1 - 1.9e-69 230.1 6.5 5.3e-20 71.7 0.0 4.7 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 KFP22902.1 - 2e-12 47.1 4.6 0.00033 20.6 0.2 5.2 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 KFP22902.1 - 6.6e-06 26.7 17.4 2.6e-05 24.8 3.0 4.0 4 0 0 4 4 4 2 Bacterial cadherin-like domain Big_9 PF17963.1 KFP22902.1 - 6.5e-05 23.6 3.5 6.5e-05 23.6 3.5 3.4 3 0 0 3 3 3 1 Bacterial Ig domain MCD PF05292.11 KFP22903.1 - 2.6e-23 82.9 0.1 3.9e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain HSBP1 PF06825.12 KFP22904.1 - 9.9e-22 76.6 9.9 1.1e-20 73.3 9.9 2.0 1 1 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KFP22904.1 - 0.042 13.7 0.2 0.21 11.5 0.2 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4351 PF14261.6 KFP22904.1 - 0.12 12.5 0.2 0.15 12.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4351) Ion_trans PF00520.31 KFP22905.1 - 2.2e-30 105.7 3.8 3.4e-26 92.0 1.8 2.2 2 0 0 2 2 2 2 Ion transport protein BTB_2 PF02214.22 KFP22905.1 - 5e-25 87.7 0.0 1.3e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KFP22905.1 - 2.9e-08 33.6 0.4 2.9e-08 33.6 0.4 2.5 3 0 0 3 3 3 1 Ion channel WAP PF00095.21 KFP22906.1 - 1.4e-06 28.6 15.1 1.4e-06 28.6 15.1 2.1 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' E1-E2_ATPase PF00122.20 KFP22907.1 - 5.2e-51 172.7 0.0 5.2e-51 172.7 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFP22907.1 - 1.1e-44 152.4 6.2 1.1e-44 152.4 6.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KFP22907.1 - 2.5e-18 65.5 0.1 6e-18 64.3 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KFP22907.1 - 1.2e-15 58.4 4.0 1.1e-14 55.2 4.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP22907.1 - 1.6e-15 56.9 0.2 3e-14 52.9 0.1 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFP22907.1 - 0.00027 20.8 1.9 0.00063 19.6 1.9 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rrf2 PF02082.20 KFP22907.1 - 0.078 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator TLD PF07534.16 KFP22908.1 - 1e-37 129.5 0.2 1.5e-37 128.9 0.2 1.3 1 0 0 1 1 1 1 TLD Fn_bind PF02986.14 KFP22908.1 - 0.072 12.8 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Fibronectin binding repeat Cofilin_ADF PF00241.20 KFP22910.1 - 3.9e-16 59.0 0.0 4.4e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Kelch_1 PF01344.25 KFP22911.1 - 1.8e-42 142.7 11.1 1.1e-09 37.7 0.1 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KFP22911.1 - 2.3e-32 110.2 3.2 6.5e-05 23.1 0.1 6.5 4 2 2 6 6 6 6 Kelch motif BTB PF00651.31 KFP22911.1 - 6.5e-28 97.2 0.8 3.5e-27 94.8 0.0 2.5 2 1 1 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.15 KFP22911.1 - 1.6e-22 78.6 5.7 8.9e-05 22.3 0.3 6.6 6 0 0 6 6 6 4 Kelch motif BACK PF07707.15 KFP22911.1 - 2.3e-21 75.8 0.3 4.5e-21 74.9 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 KFP22911.1 - 3e-20 72.0 2.5 0.0048 16.9 0.1 5.6 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFP22911.1 - 1.1e-14 54.3 0.9 0.31 11.4 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP22911.1 - 1.3e-14 53.7 2.0 1.3e-05 25.1 0.1 5.4 5 0 0 5 5 5 3 Kelch motif UCH PF00443.29 KFP22912.1 - 7.6e-39 133.7 0.0 1.1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP22912.1 - 2.2e-07 30.8 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.15 KFP22912.1 - 3.2e-05 23.3 0.0 9.5e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region LCCL PF03815.19 KFP22913.1 - 9.9e-50 166.6 10.5 3.5e-26 91.1 0.2 3.0 3 0 0 3 3 3 2 LCCL domain CAP PF00188.26 KFP22913.1 - 1.2e-21 77.8 6.1 2.1e-21 77.0 6.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.10 KFP22913.1 - 2.9e-05 24.9 0.0 0.0078 17.0 0.0 2.6 2 0 0 2 2 2 2 Histone deacetylation protein Rxt3 DUF5607 PF18355.1 KFP22913.1 - 0.0066 16.9 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5607) Hormone_recep PF00104.30 KFP22914.1 - 4.8e-40 137.3 0.2 1e-39 136.3 0.0 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KFP22914.1 - 3.1e-30 104.4 18.1 5.2e-30 103.7 18.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DHHC PF01529.20 KFP22915.1 - 4e-36 124.1 13.5 4e-36 124.1 13.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3615 PF12274.8 KFP22915.1 - 0.29 11.7 4.1 0.62 10.6 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) TRIQK PF15168.6 KFP22915.1 - 0.32 10.9 3.2 4.5 7.2 0.1 2.6 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF4191 PF13829.6 KFP22915.1 - 3 7.1 3.8 5.4 6.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) 5-FTHF_cyc-lig PF01812.20 KFP22917.1 - 6.4e-25 88.1 0.0 9.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 KFP22917.1 - 1.8e-05 24.4 0.0 0.00012 21.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bee_toxin PF17454.2 KFP22917.1 - 0.1 12.6 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Honey bee toxin IRF-3 PF10401.9 KFP22918.1 - 2.3e-66 223.0 0.1 3.1e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KFP22918.1 - 9.6e-43 144.8 0.6 1.8e-42 143.9 0.6 1.5 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KFP22918.1 - 0.00038 20.8 0.0 0.00062 20.0 0.0 1.3 1 0 0 1 1 1 1 MH2 domain COX4 PF02936.14 KFP22919.1 - 1.3e-57 193.7 0.2 1.5e-57 193.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UPF0172 PF03665.13 KFP22920.1 - 2.6e-35 122.2 0.6 2.9e-35 122.1 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Sld5 PF05916.11 KFP22921.1 - 2.6e-12 47.1 1.0 2.9e-12 47.0 1.0 1.0 1 0 0 1 1 1 1 GINS complex protein PI3K_1B_p101 PF10486.9 KFP22922.1 - 0 1254.5 7.2 0 1254.2 7.2 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Na_trans_assoc PF06512.13 KFP22922.1 - 0.0077 16.5 0.5 0.018 15.3 0.5 1.6 1 0 0 1 1 1 1 Sodium ion transport-associated FAD-SLDH PF12318.8 KFP22922.1 - 0.079 13.0 0.8 0.2 11.7 0.8 1.6 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase WRNPLPNID PF15017.6 KFP22922.1 - 6.5 7.7 9.8 11 7.0 0.0 3.3 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box DUF3585 PF12130.8 KFP22923.1 - 2.7e-22 79.4 15.4 3.9e-22 78.8 15.4 1.2 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Hep_59 PF07052.11 KFP22923.1 - 0.0049 17.6 2.5 0.12 13.1 0.1 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 NEXCaM_BD PF16644.5 KFP22923.1 - 0.029 14.6 1.2 0.029 14.6 1.2 2.1 2 0 0 2 2 2 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Histone_HNS PF00816.21 KFP22923.1 - 0.076 13.8 3.8 0.13 13.1 3.8 1.5 1 0 0 1 1 1 0 H-NS histone family DUF1027 PF06265.11 KFP22923.1 - 0.11 12.5 1.3 0.29 11.1 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) FlxA PF14282.6 KFP22923.1 - 1.9 8.5 11.3 0.24 11.4 6.7 1.8 2 0 0 2 2 2 0 FlxA-like protein DUF4200 PF13863.6 KFP22924.1 - 5.8e-22 78.3 25.2 5.8e-22 78.3 25.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Adenine_glyco PF03352.13 KFP22924.1 - 0.041 13.7 3.8 0.077 12.8 3.8 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase CENP-O PF09496.10 KFP22924.1 - 0.63 10.0 8.7 0.06 13.3 2.8 1.9 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component RGS PF00615.19 KFP22924.1 - 3.7 7.8 9.6 0.48 10.7 3.9 2.4 1 1 2 3 3 3 0 Regulator of G protein signaling domain NUDE_C PF04880.13 KFP22925.1 - 2.6e-46 158.3 13.3 6e-46 157.1 0.7 2.4 2 1 0 2 2 2 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KFP22925.1 - 0.0038 18.1 7.6 0.0038 18.1 7.6 2.9 1 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 KFP22925.1 - 0.013 15.6 8.6 0.013 15.6 8.6 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KFP22925.1 - 0.019 15.1 2.6 0.019 15.1 2.6 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF5576 PF17739.1 KFP22925.1 - 0.025 14.7 0.3 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5576) Rootletin PF15035.6 KFP22925.1 - 0.077 13.0 32.0 0.18 11.8 12.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 KFP22925.1 - 0.092 12.8 9.6 0.053 13.6 4.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFP22925.1 - 0.092 12.2 23.7 0.16 11.4 23.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 KFP22925.1 - 0.19 11.9 35.6 1.3 9.2 9.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAD_SAK_1 PF10307.9 KFP22925.1 - 0.39 10.5 7.3 1.8 8.3 7.1 1.9 1 1 1 2 2 2 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins KxDL PF10241.9 KFP22925.1 - 1.5 9.1 15.1 0.31 11.4 5.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein FlaC_arch PF05377.11 KFP22925.1 - 1.6 9.2 8.7 3.2 8.2 0.9 4.0 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 KFP22925.1 - 2.1 7.9 15.2 0.19 11.3 5.5 2.8 1 1 3 4 4 4 0 fzo-like conserved region BST2 PF16716.5 KFP22925.1 - 2.4 8.8 24.8 0.31 11.6 11.5 3.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 KFP22925.1 - 2.6 8.7 20.7 4.7 7.9 6.5 3.3 1 1 1 2 2 2 0 Initiation control protein YabA YtxH PF12732.7 KFP22925.1 - 4.5 7.9 5.9 4 8.0 0.4 3.0 2 1 1 3 3 3 0 YtxH-like protein DUF5595 PF18077.1 KFP22925.1 - 4.8 7.3 18.7 0.072 13.2 2.9 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF5595) Lectin_N PF03954.14 KFP22925.1 - 6 6.6 11.4 1.2 8.9 3.8 3.1 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.9 KFP22925.1 - 6.1 6.9 31.1 1.5 8.9 22.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KFP22925.1 - 8.4 6.5 28.5 1.3 9.1 10.1 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding zf-RING_UBOX PF13445.6 KFP22926.1 - 1.2e-09 38.1 3.7 2.5e-09 37.0 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFP22926.1 - 1.6e-06 28.3 6.2 5e-06 26.7 6.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFP22926.1 - 2.7e-05 24.0 5.1 6.4e-05 22.8 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFP22926.1 - 5.3e-05 23.0 5.1 0.00011 21.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP22926.1 - 5.5e-05 22.9 6.6 0.00012 21.8 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP22926.1 - 0.00054 19.6 5.8 0.0015 18.2 5.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KFP22926.1 - 0.17 12.1 10.4 0.1 12.8 6.9 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFP22926.1 - 0.46 10.4 9.6 9.2 6.2 9.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KFP22926.1 - 0.51 10.5 8.2 0.81 9.9 8.2 1.6 1 1 0 1 1 1 0 FYVE zinc finger PIRT PF15099.6 KFP22927.1 - 1.5e-70 234.8 3.0 1.7e-70 234.7 3.0 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM100 PF16311.5 KFP22927.1 - 3.9e-05 23.3 0.2 4.4e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 100 7TM_GPCR_Srz PF10325.9 KFP22927.1 - 0.012 14.9 1.1 0.013 14.9 1.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Phage_holin_3_6 PF07332.11 KFP22927.1 - 0.015 15.4 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III YajC PF02699.15 KFP22927.1 - 0.031 14.1 0.3 0.031 14.1 0.3 1.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2663 PF10864.8 KFP22927.1 - 0.041 14.3 0.2 0.059 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Ferric_reduct PF01794.19 KFP22927.1 - 0.045 13.9 0.4 0.081 13.1 0.4 1.6 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Neurensin PF14927.6 KFP22927.1 - 0.091 12.5 2.3 1.2 8.8 0.1 2.1 1 1 1 2 2 2 0 Neurensin SdpI PF13630.6 KFP22927.1 - 0.095 12.8 3.2 0.6 10.3 3.3 2.0 1 1 0 1 1 1 0 SdpI/YhfL protein family EphA2_TM PF14575.6 KFP22927.1 - 0.29 12.0 3.2 12 6.8 3.2 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3040 PF11239.8 KFP22927.1 - 2.9 8.2 4.2 42 4.5 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Lactamase_B_2 PF12706.7 KFP22929.1 - 2.3e-12 46.9 0.2 1e-10 41.5 0.6 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KFP22929.1 - 2.8e-12 46.1 0.0 3.5e-11 42.6 0.0 2.8 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.27 KFP22929.1 - 0.00067 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DASH_Ask1 PF08655.10 KFP22929.1 - 0.048 13.6 0.1 0.88 9.5 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Ask1 RPEL PF02755.15 KFP22930.1 - 2e-18 65.4 6.7 9.6e-07 28.3 0.0 3.5 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.27 KFP22930.1 - 4.8e-10 39.0 2.1 7.2e-10 38.4 0.1 2.3 2 0 0 2 2 2 1 SAP domain Pkinase PF00069.25 KFP22931.1 - 1.4e-60 204.9 0.0 1.7e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP22931.1 - 7.7e-39 133.5 0.0 9.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP22931.1 - 5.7e-07 29.1 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFP22931.1 - 0.00015 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KFP22931.1 - 0.00054 19.0 0.0 0.00082 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFP22931.1 - 0.0029 16.5 0.0 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DXP_redisom_C PF08436.12 KFP22931.1 - 0.055 13.6 0.0 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain APH PF01636.23 KFP22931.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFP22931.1 - 0.16 11.5 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SCO1-SenC PF02630.14 KFP22932.1 - 1.1e-48 164.5 0.0 1.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFP22932.1 - 2.6e-06 27.3 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFP22932.1 - 0.0014 18.9 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TetR_C_8 PF14278.6 KFP22933.1 - 0.041 14.0 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region WD40 PF00400.32 KFP22935.1 - 7.6e-05 23.4 1.7 0.99 10.4 1.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 KFP22935.1 - 0.00019 20.9 0.0 0.23 10.8 0.0 2.4 3 0 0 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 KFP22935.1 - 0.011 16.1 0.0 7.9 6.9 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain UBA PF00627.31 KFP22937.1 - 1.8e-06 27.7 0.8 0.00011 22.0 0.0 3.4 4 0 0 4 4 4 1 UBA/TS-N domain UBA_3 PF09288.10 KFP22937.1 - 0.003 17.3 0.7 1.1 9.1 0.0 3.2 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain DUF1421 PF07223.11 KFP22937.1 - 0.069 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain (DUF1421) UBA_2 PF08587.11 KFP22937.1 - 0.11 12.6 0.2 25 5.1 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) MerR-DNA-bind PF09278.11 KFP22937.1 - 0.15 12.6 1.5 0.21 12.2 0.1 2.1 2 0 0 2 2 2 0 MerR, DNA binding DUF2203 PF09969.9 KFP22937.1 - 0.37 11.5 2.3 1.1 9.9 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Kinesin PF00225.23 KFP22938.1 - 5.3e-51 173.5 1.7 5.3e-51 173.5 1.7 1.6 2 0 0 2 2 2 1 Kinesin motor domain SAM_1 PF00536.30 KFP22938.1 - 0.0014 19.0 0.1 0.0034 17.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NUDIX PF00293.28 KFP22939.1 - 2e-19 69.9 0.2 2.5e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain I-set PF07679.16 KFP22939.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ricin_B_lectin PF00652.22 KFP22941.1 - 1.8e-09 37.9 6.6 1.8e-07 31.5 1.5 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KFP22941.1 - 2.9e-05 23.7 0.2 5e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain Glyco_hydro_31 PF01055.26 KFP22942.1 - 3.1e-38 132.1 0.5 3.1e-21 76.1 0.7 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Melibiase PF02065.18 KFP22942.1 - 0.062 12.2 0.1 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 Melibiase Glyco_hydro_31 PF01055.26 KFP22944.1 - 1.3e-58 199.3 1.3 9.1e-35 120.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Melibiase PF02065.18 KFP22944.1 - 0.018 14.0 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Melibiase DPM2 PF07297.12 KFP22944.1 - 1.4 9.3 3.1 53 4.2 0.0 2.6 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) SMRP1 PF15181.6 KFP22946.1 - 1.7e-60 204.9 10.3 1.4e-58 198.5 10.3 2.0 1 1 0 1 1 1 1 Spermatid-specific manchette-related protein 1 WW_like PF17890.1 KFP22946.1 - 0.13 12.4 0.4 0.33 11.1 0.4 1.7 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain FAM219A PF15260.6 KFP22947.1 - 3.3e-48 163.2 2.6 4.1e-48 162.9 2.6 1.1 1 0 0 1 1 1 1 Protein family FAM219A WD40 PF00400.32 KFP22950.1 - 3.1e-10 40.5 11.8 0.0049 17.7 1.6 6.1 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP22950.1 - 3.8e-06 27.1 0.4 2.5 8.5 0.0 5.0 3 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP22950.1 - 0.0094 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4191 PF13829.6 KFP22950.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Neur_chan_memb PF02932.16 KFP22950.1 - 2.7 8.0 4.7 4.9 7.1 4.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 KFP22950.1 - 8 6.2 12.0 13 5.5 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Alba PF01918.21 KFP22952.1 - 2.5e-16 59.2 0.8 3.4e-16 58.8 0.8 1.2 1 0 0 1 1 1 1 Alba Hit1_C PF18268.1 KFP22952.1 - 0.18 11.9 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal Dynactin_p22 PF07426.11 KFP22953.1 - 3.3e-49 166.9 7.3 3.8e-49 166.8 7.3 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 Jnk-SapK_ap_N PF09744.9 KFP22953.1 - 0.00046 20.4 0.7 0.00076 19.7 0.6 1.4 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 Myb_DNA-bind_3 PF12776.7 KFP22953.1 - 0.11 13.5 0.1 0.19 12.8 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DivIC PF04977.15 KFP22953.1 - 0.21 11.4 3.7 2.8 7.8 0.1 2.7 2 1 1 3 3 3 0 Septum formation initiator ARID PF01388.21 KFP22954.1 - 2.4e-21 76.2 0.0 4.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ketoacyl-synt PF00109.26 KFP22954.1 - 0.0035 16.9 0.1 0.0053 16.4 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NeuB PF03102.14 KFP22954.1 - 0.05 13.0 0.3 0.14 11.6 0.3 1.7 1 1 0 1 1 1 0 NeuB family ERG2_Sigma1R PF04622.12 KFP22955.1 - 1.8e-64 216.9 0.4 2.1e-64 216.7 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein GalP_UDP_transf PF01087.22 KFP22956.1 - 1.9e-65 220.7 0.0 2.7e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFP22956.1 - 4.2e-22 78.6 0.1 8.8e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KFP22956.1 - 0.027 15.2 0.0 0.14 12.9 0.0 1.9 2 0 0 2 2 2 0 HIT domain fn3 PF00041.21 KFP22957.1 - 1.5e-07 31.6 1.7 6.5e-07 29.6 0.2 2.6 2 1 0 2 2 2 1 Fibronectin type III domain Ig_5 PF16681.5 KFP22957.1 - 1.1e-05 25.7 0.2 2.4e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_2 PF13895.6 KFP22957.1 - 7.9e-05 22.9 0.2 0.00026 21.2 0.2 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KFP22957.1 - 0.00021 21.8 0.1 0.00021 21.8 0.1 2.8 3 1 0 3 3 3 1 Immunoglobulin domain Ig_4 PF16680.5 KFP22957.1 - 0.0026 18.0 0.1 0.0052 17.0 0.1 1.5 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain I-set PF07679.16 KFP22957.1 - 0.011 15.7 0.7 0.18 11.9 0.2 2.8 2 0 0 2 2 2 0 Immunoglobulin I-set domain IL12p40_C PF10420.9 KFP22957.1 - 0.06 13.9 0.1 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Ig_2 PF13895.6 KFP22958.1 - 0.00034 20.9 0.0 0.0031 17.8 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KFP22958.1 - 0.00049 20.6 0.1 0.0028 18.2 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain IL12p40_C PF10420.9 KFP22958.1 - 0.0019 18.7 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 Cytokine interleukin-12p40 C-terminus ISK_Channel PF02060.15 KFP22958.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Slow voltage-gated potassium channel EpoR_lig-bind PF09067.10 KFP22958.1 - 0.022 15.0 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding TMEM154 PF15102.6 KFP22958.1 - 0.034 14.1 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family ig PF00047.25 KFP22958.1 - 0.037 14.2 0.1 0.48 10.6 0.0 2.7 2 1 0 2 2 2 0 Immunoglobulin domain Stevor PF17410.2 KFP22958.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 KFP22958.1 - 0.24 10.1 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sarcolipin PF05366.11 KFP22958.1 - 0.37 10.5 1.4 0.7 9.6 1.4 1.3 1 0 0 1 1 1 0 Sarcolipin IL8 PF00048.20 KFP22959.1 - 3.8e-19 68.6 0.3 4.3e-19 68.4 0.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Zf_RING PF16744.5 KFP22960.1 - 7e-38 128.6 6.7 1.3e-37 127.7 6.7 1.5 1 0 0 1 1 1 1 KIAA1045 RING finger EF-hand_6 PF13405.6 KFP22960.1 - 1.8e-05 24.3 0.0 0.035 14.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFP22960.1 - 3.4e-05 23.1 0.1 0.12 12.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KFP22960.1 - 5.2e-05 23.6 0.4 0.53 10.8 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain pair Zn_ribbon_17 PF17120.5 KFP22960.1 - 5.3e-05 22.8 1.2 5.3e-05 22.8 1.2 2.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 KFP22960.1 - 0.0055 16.6 6.9 0.022 14.6 6.9 2.0 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KFP22960.1 - 0.015 15.1 1.1 0.015 15.1 1.1 2.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_8 PF13833.6 KFP22960.1 - 0.022 14.6 0.1 0.74 9.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair zf-HC5HC2H PF13771.6 KFP22960.1 - 0.04 14.2 2.9 0.16 12.2 2.9 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_4 PF16866.5 KFP22960.1 - 0.13 12.3 5.5 0.11 12.6 3.2 2.2 1 1 1 2 2 2 0 PHD-finger EF-hand_5 PF13202.6 KFP22960.1 - 0.19 11.3 0.1 3.4 7.3 0.1 2.6 2 0 0 2 2 2 0 EF hand C1_2 PF03107.16 KFP22960.1 - 0.42 11.0 3.2 0.87 10.0 0.9 2.3 2 0 0 2 2 2 0 C1 domain DnaJ_C PF01556.18 KFP22962.1 - 2.1e-45 154.4 0.1 2.8e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFP22962.1 - 5e-29 100.2 4.4 8.1e-29 99.5 4.4 1.3 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.29 KFP22963.1 - 5.8e-93 308.3 0.0 1.9e-46 157.8 0.0 2.9 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFP22963.1 - 1.1e-27 95.6 6.7 3.7e-13 49.0 0.2 3.2 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 KFP22963.1 - 2.4e-22 78.9 0.4 1.2e-21 76.7 0.5 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KFP22963.1 - 4.8e-14 52.4 0.0 1.8e-05 24.6 0.0 3.3 4 0 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 KFP22963.1 - 1.3e-12 47.3 0.0 2.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 KFP22963.1 - 2.1e-12 47.8 5.8 0.00071 20.0 1.6 5.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 KFP22963.1 - 2.7e-10 40.5 0.0 0.00015 22.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFP22963.1 - 4.3e-10 39.7 0.0 0.00016 21.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFP22963.1 - 6.5e-09 36.2 0.4 0.022 15.1 0.0 4.2 3 2 1 4 4 2 2 AAA domain Vps4_C PF09336.10 KFP22963.1 - 7.2e-09 35.5 0.9 3.1e-05 23.9 0.1 2.8 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 KFP22963.1 - 1.1e-08 34.7 0.2 0.0016 17.7 0.0 2.7 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_2 PF07724.14 KFP22963.1 - 2e-08 34.6 0.0 0.0049 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KFP22963.1 - 1.5e-07 32.0 0.0 0.026 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFP22963.1 - 2e-07 31.4 0.0 0.0068 16.8 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 KFP22963.1 - 3.3e-07 30.4 0.0 0.025 14.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 KFP22963.1 - 3.5e-07 29.8 0.1 0.019 14.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFP22963.1 - 7.7e-07 29.0 0.0 0.056 13.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KFP22963.1 - 1.3e-06 28.2 0.0 0.0026 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KFP22963.1 - 3.5e-06 26.3 0.1 0.036 13.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KFP22963.1 - 5.4e-06 26.7 0.2 0.19 12.0 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_7 PF12775.7 KFP22963.1 - 8e-06 25.5 0.0 0.071 12.6 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 KFP22963.1 - 9.7e-06 26.1 0.0 0.011 16.3 0.0 3.5 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.13 KFP22963.1 - 2.2e-05 23.8 0.0 0.013 14.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KFP22963.1 - 3.5e-05 23.8 0.2 0.26 11.2 0.0 3.6 3 2 1 5 5 3 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KFP22963.1 - 5.6e-05 23.0 0.0 0.0019 18.0 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KFP22963.1 - 6.8e-05 22.9 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFP22963.1 - 7.1e-05 23.2 0.0 0.96 9.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KFP22963.1 - 0.00014 21.6 0.0 0.52 10.0 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KFP22963.1 - 0.00019 21.3 0.1 0.95 9.2 0.0 3.9 4 1 0 4 4 3 1 Bacterial dnaA protein ATPase PF06745.13 KFP22963.1 - 0.00023 20.6 0.2 0.49 9.7 0.0 2.9 3 0 0 3 3 2 2 KaiC NACHT PF05729.12 KFP22963.1 - 0.00029 20.8 0.1 0.31 10.9 0.0 3.1 2 1 0 3 3 3 1 NACHT domain NB-ARC PF00931.22 KFP22963.1 - 0.00035 19.8 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KFP22963.1 - 0.00056 19.2 0.0 0.55 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.9 KFP22963.1 - 0.00068 19.0 0.0 0.44 9.7 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KFP22963.1 - 0.00079 19.1 0.6 1.7 8.2 0.0 3.2 2 2 1 3 3 3 2 AAA domain AAA_3 PF07726.11 KFP22963.1 - 0.0011 18.9 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KFP22963.1 - 0.0013 18.8 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KFP22963.1 - 0.0013 18.2 0.5 1.8 7.9 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 KFP22963.1 - 0.0016 18.6 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 KFP22963.1 - 0.0026 17.6 0.2 2.4 7.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KFP22963.1 - 0.0037 17.2 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 KFP22963.1 - 0.0046 17.3 1.8 3.3 8.0 0.2 3.4 3 1 0 4 4 2 1 AAA domain AAA_30 PF13604.6 KFP22963.1 - 0.021 14.5 0.4 3 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFP22963.1 - 0.028 14.3 0.1 5.5 6.9 0.0 3.2 3 0 0 3 3 3 0 NTPase SKI PF01202.22 KFP22963.1 - 0.032 14.4 0.0 5.9 7.0 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase UFD1 PF03152.14 KFP22963.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 KFP22963.1 - 0.049 13.4 0.0 9.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 KFP22963.1 - 0.071 13.2 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.12 KFP22963.1 - 0.086 12.5 0.0 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 KFP22963.1 - 0.14 11.9 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TPR_19 PF14559.6 KFP22964.1 - 4e-12 46.5 15.6 0.0014 19.0 0.3 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP22964.1 - 2.8e-11 42.6 9.6 0.0088 16.1 0.0 7.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFP22964.1 - 1.7e-07 30.7 9.0 6.8e-05 22.5 0.1 5.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP22964.1 - 3.6e-07 30.5 21.5 0.0055 17.4 0.0 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP22964.1 - 2.4e-05 24.6 18.4 0.00072 19.8 0.4 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFP22964.1 - 5.7e-05 23.0 0.9 3.2 8.2 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP22964.1 - 0.00062 19.9 9.6 0.12 12.6 1.4 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFP22964.1 - 0.0064 16.3 17.5 1.1 9.2 0.1 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP22964.1 - 0.055 13.5 17.5 1.2 9.4 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFP22964.1 - 0.12 13.0 24.8 12 6.7 3.8 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFP22964.1 - 0.18 12.2 1.8 39 4.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFP22964.1 - 0.22 11.2 1.7 6.7 6.5 0.0 3.9 4 0 0 4 4 4 0 TPR repeat NinF PF05810.12 KFP22964.1 - 0.4 10.6 2.2 6.8 6.6 0.5 2.7 2 0 0 2 2 2 0 NinF protein TPR_20 PF14561.6 KFP22964.1 - 0.52 10.7 10.2 5.7 7.3 0.2 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFP22964.1 - 1.3 9.2 9.7 5.1 7.3 3.1 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFP22964.1 - 8.6 7.2 15.6 13 6.7 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Band_7 PF01145.25 KFP22965.1 - 6.6e-31 107.7 1.0 6.6e-31 107.7 1.0 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFP22965.1 - 1.1e-17 63.9 1.1 1.1e-17 63.9 1.1 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 DUF4769 PF15992.5 KFP22965.1 - 0.032 14.0 0.4 0.048 13.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Band_7_1 PF13421.6 KFP22965.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Chromosome_seg PF13889.6 KFP22966.1 - 1e-18 67.2 0.4 2.2e-18 66.1 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KFP22966.1 - 1.1e-13 51.5 0.1 2.4e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) C2 PF00168.30 KFP22970.1 - 3.6e-09 36.8 0.1 4.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain PhoLip_ATPase_C PF16212.5 KFP22975.1 - 9.2e-83 277.8 29.7 9.2e-83 277.8 29.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFP22975.1 - 8.9e-23 79.8 8.2 2.4e-22 78.4 8.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFP22975.1 - 4.6e-12 46.7 0.6 4.1e-06 27.2 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFP22975.1 - 1.3e-10 41.2 0.0 2.9e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFP22975.1 - 3.1e-06 26.8 0.0 1.1e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFP22975.1 - 0.00035 20.4 0.1 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP22975.1 - 0.074 13.1 1.3 0.71 9.9 0.3 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Y_phosphatase PF00102.27 KFP22977.1 - 4.4e-100 334.1 0.0 9.4e-81 270.8 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KFP22977.1 - 6.2e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KFP22977.1 - 0.0018 18.3 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP22977.1 - 0.2 11.8 0.7 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP22978.1 - 1.6e-15 57.3 0.0 1.7e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFP22978.1 - 0.00029 20.7 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.17 KFP22979.1 - 4e-37 127.9 0.0 5.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP22979.1 - 7.7e-35 120.5 0.0 1.5e-34 119.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFP22979.1 - 0.00011 21.2 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFP22979.1 - 0.0015 18.0 0.0 0.0035 16.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP22979.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lectin_C PF00059.21 KFP22980.1 - 3.4e-07 31.0 4.5 1.1e-06 29.3 4.5 1.9 1 1 0 1 1 1 1 Lectin C-type domain Spc7 PF08317.11 KFP22980.1 - 0.0034 16.3 3.7 0.0065 15.4 3.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3301 PF11743.8 KFP22980.1 - 0.0038 16.9 2.9 0.0073 16.0 2.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3301) Chordopox_A33R PF05966.12 KFP22980.1 - 0.022 14.0 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Ly49 PF08391.10 KFP22980.1 - 0.032 14.6 0.1 0.063 13.6 0.1 1.6 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region ATG16 PF08614.11 KFP22980.1 - 0.039 14.2 6.7 0.063 13.5 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HemX PF04375.14 KFP22980.1 - 0.07 12.4 4.2 0.099 11.9 4.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Acyl-CoA_dh_2 PF08028.11 KFP22980.1 - 0.24 11.7 3.6 0.44 10.8 3.6 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HIP1_clath_bdg PF16515.5 KFP22980.1 - 0.37 11.4 6.5 0.61 10.7 5.7 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3522 PF12036.8 KFP22981.1 - 3e-09 37.4 4.3 4.9e-09 36.7 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Plasmod_Pvs28 PF06247.11 KFP22981.1 - 0.67 10.3 5.6 1.9 8.8 5.6 1.7 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_2 PF07974.13 KFP22981.1 - 5.2 7.5 8.5 16 5.9 8.5 1.9 1 0 0 1 1 1 0 EGF-like domain ANF_receptor PF01094.28 KFP22983.1 - 4e-15 55.8 0.1 4.9e-15 55.5 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KFP22983.1 - 0.033 13.8 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein PSP94 PF05825.11 KFP22984.1 - 6.5e-08 33.0 5.1 8.5e-08 32.7 5.1 1.1 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.18 KFP22984.1 - 0.0012 19.1 3.5 0.0024 18.2 3.5 1.6 1 1 0 1 1 1 1 von Willebrand factor type C domain TILa PF12714.7 KFP22984.1 - 0.074 13.0 7.6 0.14 12.1 7.6 1.6 1 1 0 1 1 1 0 TILa domain Rgp1 PF08737.10 KFP22985.1 - 2.8e-34 119.0 0.4 4e-25 88.9 0.0 2.1 1 1 0 2 2 2 2 Rgp1 DUF608 PF04685.13 KFP22986.1 - 9.8e-173 574.4 6.5 1.3e-172 573.9 6.5 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 KFP22986.1 - 5.2e-107 357.9 0.0 8.5e-107 357.2 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Bac_rhamnosid6H PF17389.2 KFP22986.1 - 0.013 14.8 0.6 0.025 13.8 0.6 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 KFP22986.1 - 0.031 13.2 0.1 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF5127 PF17168.4 KFP22986.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) FrhB_FdhB_N PF04422.13 KFP22986.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Avidin PF01382.17 KFP22987.1 - 1.4e-41 141.6 2.4 1.5e-41 141.4 2.4 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KFP22988.1 - 3.6e-31 108.0 0.4 4e-31 107.9 0.4 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KFP22989.1 - 3.9e-22 78.9 0.0 4.4e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Avidin family Tropomyosin PF00261.20 KFP22990.1 - 1.3e-99 332.3 84.4 6e-96 320.4 58.1 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KFP22990.1 - 1.7e-38 132.0 70.6 9.5e-34 116.6 41.5 3.3 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.12 KFP22990.1 - 4.9e-07 29.8 30.5 0.00036 20.5 4.8 3.7 1 1 4 5 5 5 3 Laminin Domain II CLZ PF16526.5 KFP22990.1 - 1.5e-06 28.4 45.5 5.6e-05 23.4 10.0 5.1 3 2 2 5 5 5 4 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DHR10 PF18595.1 KFP22990.1 - 0.0022 18.0 14.5 0.0022 18.0 14.5 4.3 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain ERM PF00769.19 KFP22990.1 - 0.0027 17.6 71.3 0.25 11.1 11.9 3.0 1 1 2 3 3 3 1 Ezrin/radixin/moesin family ATG16 PF08614.11 KFP22990.1 - 0.003 17.8 54.8 0.021 15.0 19.3 3.6 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) YscO PF07321.12 KFP22990.1 - 0.0044 17.0 2.4 0.0044 17.0 2.4 4.7 1 1 4 5 5 5 1 Type III secretion protein YscO HrpB7 PF09486.10 KFP22990.1 - 0.011 16.1 49.7 0.069 13.5 14.4 4.7 1 1 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 KFP22990.1 - 0.015 15.2 8.1 0.015 15.2 8.1 6.2 1 1 6 7 7 7 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KFP22990.1 - 0.016 15.2 63.4 0.019 15.0 27.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KFP22990.1 - 0.018 15.6 0.4 0.018 15.6 0.4 5.6 1 1 4 5 5 5 0 SlyX SNARE PF05739.19 KFP22990.1 - 0.018 15.0 7.3 2.3 8.3 0.1 3.8 3 0 0 3 3 3 0 SNARE domain Laminin_I PF06008.14 KFP22990.1 - 0.048 13.4 46.9 0.39 10.4 13.2 3.1 2 1 0 3 3 3 0 Laminin Domain I Baculo_PEP_C PF04513.12 KFP22990.1 - 0.057 13.5 8.3 0.99 9.4 1.1 2.9 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KFP22990.1 - 0.074 13.5 0.6 0.074 13.5 0.6 4.4 1 1 3 4 4 4 0 Protein of unknown function DUF16 MscS_porin PF12795.7 KFP22990.1 - 0.089 12.3 41.5 1.6 8.2 11.1 3.0 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain HOOK PF05622.12 KFP22990.1 - 0.29 9.2 54.6 0.06 11.5 14.4 2.2 1 1 1 2 2 2 0 HOOK protein Golgin_A5 PF09787.9 KFP22990.1 - 0.38 10.2 52.8 0.71 9.3 16.7 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 Spc7 PF08317.11 KFP22990.1 - 0.56 9.0 60.2 0.72 8.7 28.7 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KFP22990.1 - 0.7 9.9 30.0 0.43 10.6 1.4 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KFP22990.1 - 0.8 9.3 60.4 0.086 12.5 11.9 3.6 1 1 2 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease FPP PF05911.11 KFP22990.1 - 1.2 7.3 57.3 0.086 11.0 28.4 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil ADIP PF11559.8 KFP22990.1 - 1.3 9.1 45.5 1.3 9.1 5.3 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KFP22990.1 - 1.3 9.2 30.6 0.19 11.9 5.2 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KFP22990.1 - 1.3 9.4 51.6 9.3 6.7 26.4 3.1 1 1 2 3 3 3 0 Fez1 Exonuc_VII_L PF02601.15 KFP22990.1 - 3.2 7.3 32.5 5.4 6.5 15.1 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit TTKRSYEDQ PF10212.9 KFP22990.1 - 3.9 6.4 35.0 0.31 10.0 12.9 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FbpA PF05833.11 KFP22990.1 - 3.9 6.1 45.7 4.4 5.9 42.3 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) DUF745 PF05335.13 KFP22990.1 - 4.4 7.0 47.2 0.8 9.4 22.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF745) T3SSipB PF16535.5 KFP22990.1 - 4.6 7.7 44.9 2 8.9 15.4 4.6 1 1 2 3 3 2 0 Type III cell invasion protein SipB YpjP PF14005.6 KFP22990.1 - 5.3 7.1 12.5 0.53 10.3 1.0 2.6 2 1 0 2 2 2 0 YpjP-like protein Fmp27_WPPW PF10359.9 KFP22990.1 - 6.4 5.5 36.6 1.2 7.9 14.2 2.8 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF4164 PF13747.6 KFP22990.1 - 6.6 7.1 52.5 0.18 12.1 11.7 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF4164) GAS PF13851.6 KFP22990.1 - 8.9 5.6 62.4 2.7 7.3 25.4 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Aph-1 PF06105.12 KFP22991.1 - 4.6e-85 284.7 13.0 5.2e-85 284.5 13.0 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.11 KFP22991.1 - 0.012 14.4 0.4 0.018 13.9 0.4 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD OST3_OST6 PF04756.13 KFP22991.1 - 0.21 10.9 5.9 0.062 12.7 1.4 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Carb_anhydrase PF00194.21 KFP22992.1 - 3.6e-62 210.2 0.1 8.9e-32 110.6 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase DUF4730 PF15873.5 KFP22992.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) LapA_dom PF06305.11 KFP22992.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SH2 PF00017.24 KFP22993.1 - 0.0018 18.3 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 SH2 domain ER-remodelling PF14755.6 KFP22994.1 - 0.021 15.1 4.2 0.023 15.0 4.2 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller Collagen PF01391.18 KFP22995.1 - 1.8e-14 53.2 48.4 7.5e-08 32.0 26.3 2.4 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) cEGF PF12662.7 KFP22995.1 - 3.5e-10 39.6 9.3 2.4e-05 24.1 1.5 3.0 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 KFP22995.1 - 2.9e-09 37.0 8.7 2.9e-09 37.0 8.7 3.0 3 1 0 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 KFP22995.1 - 6.2e-09 36.0 28.5 1.5e-08 34.7 9.0 2.8 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF PF00008.27 KFP22995.1 - 0.00042 20.5 18.2 0.016 15.5 4.7 2.9 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.7 KFP22995.1 - 0.011 15.9 21.8 0.18 12.0 4.6 2.9 2 0 0 2 2 2 0 EGF domain Tme5_EGF_like PF09064.10 KFP22995.1 - 0.022 14.6 5.0 0.022 14.6 5.0 2.7 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like PDZ PF00595.24 KFP22997.1 - 3.7e-52 174.6 5.6 1.7e-20 73.1 0.5 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KFP22997.1 - 6.2e-31 106.0 1.9 1.5e-08 34.3 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KFP22997.1 - 2.3e-16 59.9 0.1 0.0014 18.9 0.0 4.9 5 0 0 5 5 5 4 PDZ domain GPP34 PF05719.11 KFP23001.1 - 1.1e-53 182.3 0.3 1.3e-53 182.1 0.3 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.13 KFP23001.1 - 0.025 14.3 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Myotub-related PF06602.14 KFP23002.1 - 4.1e-53 180.6 6.1 4.2e-49 167.4 4.2 2.2 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.8 KFP23002.1 - 6.2e-40 136.0 0.1 1.2e-39 135.1 0.1 1.5 1 0 0 1 1 1 1 Myotubularin-associated protein PC4 PF02229.16 KFP23003.1 - 1.4e-25 88.7 0.4 2.1e-25 88.1 0.4 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.11 KFP23003.1 - 0.024 14.4 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 QLQ RNA_pol_Rpc4 PF05132.14 KFP23003.1 - 0.044 14.2 3.3 0.047 14.1 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 ANF_receptor PF01094.28 KFP23005.1 - 1.9e-24 86.4 0.1 2.3e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF4690 PF15756.5 KFP23005.1 - 0.053 14.1 0.0 0.099 13.3 0.0 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage tRNA-synt_2b PF00587.25 KFP23006.1 - 6.7e-36 123.9 0.0 1.3e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFP23006.1 - 1.6e-20 73.0 0.1 3.6e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KFP23006.1 - 3e-18 65.6 0.0 2.8e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KFP23006.1 - 1.5e-12 47.4 0.1 3.6e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TSP_1 PF00090.19 KFP23007.1 - 3e-37 126.6 122.8 8.2e-10 38.8 7.9 10.4 10 0 0 10 10 10 8 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 KFP23007.1 - 3e-34 117.5 0.0 9e-34 115.9 0.0 1.9 2 0 0 2 2 2 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.19 KFP23007.1 - 4.8e-32 111.1 0.4 1.2e-31 109.8 0.4 1.7 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KFP23007.1 - 8.3e-27 94.4 0.0 1.8e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KFP23007.1 - 4.3e-21 75.2 7.8 4.3e-21 75.2 7.8 6.7 6 2 0 6 6 6 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KFP23007.1 - 4.8e-15 56.2 0.8 1.8e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFP23007.1 - 2.6e-08 34.4 0.2 6.8e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFP23007.1 - 7.1e-05 22.8 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFP23007.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 KFP23007.1 - 1 10.2 6.4 7.8 7.3 6.4 2.8 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain 7tm_1 PF00001.21 KFP23008.1 - 4.7e-48 163.8 15.6 5.8e-48 163.5 15.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_2 PF13347.6 KFP23009.1 - 5.3e-06 25.3 7.0 5.3e-06 25.3 7.0 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein DUF2298 PF10060.9 KFP23009.1 - 0.0099 14.6 1.1 0.0099 14.6 1.1 2.0 2 0 0 2 2 2 1 Uncharacterized membrane protein (DUF2298) CoA_transf_3 PF02515.17 KFP23010.1 - 2.9e-54 184.6 0.0 3.3e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III C1q PF00386.21 KFP23011.1 - 4.2e-33 114.2 3.4 5.2e-33 114.0 3.4 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 KFP23011.1 - 5.9e-13 48.4 57.1 3.1e-10 39.7 32.5 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Baculo_LEF-3 PF05847.11 KFP23011.1 - 0.042 13.1 0.1 0.052 12.7 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Rad1 PF02144.16 KFP23013.1 - 5.8e-65 219.1 0.5 6.8e-65 218.9 0.5 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.15 KFP23013.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Brix PF04427.18 KFP23014.1 - 4.1e-41 141.2 0.7 4.1e-41 141.2 0.7 1.6 2 0 0 2 2 2 1 Brix domain zf-C2H2_jaz PF12171.8 KFP23015.1 - 6.4e-10 39.1 1.1 6.4e-10 39.1 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFP23015.1 - 1.8e-07 31.3 8.6 1.4e-06 28.5 1.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KFP23015.1 - 4.7e-06 26.9 7.3 0.013 15.8 0.5 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFP23015.1 - 0.0091 16.8 5.6 0.96 10.5 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2779 PF11074.8 KFP23015.1 - 7.7 7.0 15.2 13 6.3 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function(DUF2779) zf-C2H2_6 PF13912.6 KFP23015.1 - 8.3 6.5 9.7 5.1 7.2 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Aminotran_3 PF00202.21 KFP23016.1 - 3.2e-94 315.9 0.0 4.5e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFP23016.1 - 0.00044 19.5 0.0 0.01 15.0 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II EpoR_lig-bind PF09067.10 KFP23018.1 - 9.6e-52 173.6 4.7 6.9e-26 90.5 0.1 3.4 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.10 KFP23018.1 - 2.3e-19 69.6 7.4 2.1e-09 37.7 0.1 3.3 3 0 0 3 3 3 2 Interleukin-6 receptor alpha chain, binding fn3 PF00041.21 KFP23018.1 - 1.1e-15 57.7 13.6 4.9e-05 23.6 0.7 5.1 5 1 0 5 5 5 4 Fibronectin type III domain DUF3047 PF11249.8 KFP23018.1 - 0.033 13.6 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) Tissue_fac PF01108.17 KFP23018.1 - 0.06 13.2 10.3 12 5.8 0.2 4.6 4 0 0 4 4 4 0 Tissue factor Lipase3_N PF03893.16 KFP23018.1 - 0.16 12.1 0.4 7.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Lipase 3 N-terminal region FN3_7 PF18447.1 KFP23021.1 - 2.1e-38 130.5 6.1 3.8e-38 129.7 6.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Glycophorin_A PF01102.18 KFP23021.1 - 0.043 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 KFP23021.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family NADH_dehy_S2_C PF06444.11 KFP23021.1 - 5.5 7.6 8.7 8.9 6.9 0.1 2.8 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus EF-hand_1 PF00036.32 KFP23022.1 - 8.8e-25 84.4 10.8 6.4e-09 34.7 0.7 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFP23022.1 - 4.5e-23 79.2 9.7 3.4e-07 29.7 0.0 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KFP23022.1 - 2e-18 66.6 10.4 2e-08 34.6 5.1 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFP23022.1 - 5.7e-13 47.7 18.1 5.9e-05 22.4 2.4 5.1 5 1 1 6 6 6 3 EF hand EF-hand_8 PF13833.6 KFP23022.1 - 9.3e-13 47.8 13.8 2.5e-07 30.4 1.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KFP23022.1 - 9.9e-05 22.2 2.5 0.1 12.6 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand YugN PF08868.10 KFP23022.1 - 0.0088 16.0 0.3 0.043 13.7 0.0 1.9 2 0 0 2 2 2 1 YugN-like family Phage_XkdX PF09693.10 KFP23022.1 - 0.049 13.7 0.6 4.1 7.5 0.0 2.9 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) SPARC_Ca_bdg PF10591.9 KFP23022.1 - 0.075 13.4 0.1 5.9 7.2 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KFP23022.1 - 0.16 11.9 0.4 1.5 8.7 0.4 2.6 2 1 1 3 3 3 0 EF hand EF-hand_9 PF14658.6 KFP23022.1 - 1.1 9.6 4.6 3.4 8.1 0.1 3.3 3 2 0 3 3 3 0 EF-hand domain LMBR1 PF04791.16 KFP23023.1 - 4.4e-188 626.3 25.7 4.4e-188 626.3 25.7 1.3 2 0 0 2 2 2 1 LMBR1-like membrane protein F-box-like PF12937.7 KFP23024.1 - 5.9e-16 58.1 1.8 1.7e-15 56.6 1.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFP23024.1 - 3.4e-08 33.2 0.9 3.4e-08 33.2 0.9 2.3 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 KFP23024.1 - 0.015 15.3 7.9 0.6 10.3 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 KFP23024.1 - 0.047 14.2 17.2 30 5.7 0.1 7.4 6 2 0 6 6 6 0 Leucine Rich Repeat F-box_5 PF18511.1 KFP23024.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box NAD_kinase PF01513.21 KFP23025.1 - 2.9e-10 39.8 0.0 4.4e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFP23025.1 - 0.0014 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CE2_N PF17996.1 KFP23025.1 - 0.029 14.3 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal TPALS PF18178.1 KFP23025.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family DUF4988 PF16378.5 KFP23025.1 - 0.12 12.0 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function SDF PF00375.18 KFP23028.1 - 4.5e-134 447.4 32.5 5.1e-134 447.2 32.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.7 KFP23028.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF1270 PF06900.11 KFP23028.1 - 0.48 10.8 5.3 5.6 7.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Cohesin_HEAT PF12765.7 KFP23032.1 - 1.5e-13 50.8 0.2 2.3e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFP23032.1 - 7.6e-06 25.8 0.5 0.0025 17.9 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 KFP23032.1 - 0.00053 20.4 0.2 0.0091 16.5 0.1 2.2 1 1 1 2 2 2 1 HEAT-like repeat Cnd3 PF12719.7 KFP23032.1 - 0.0013 18.0 0.1 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.8 KFP23032.1 - 0.079 12.9 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) CcmH PF03918.14 KFP23032.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein CLASP_N PF12348.8 KFP23032.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 CLASP N terminal Nipped-B_C PF12830.7 KFP23033.1 - 3.6e-68 229.3 1.3 3.6e-68 229.3 1.3 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 KFP23033.1 - 0.00085 19.7 0.0 4 7.9 0.0 3.6 2 1 0 2 2 2 2 HEAT repeats DNA_repr_REX1B PF14966.6 KFP23033.1 - 0.019 15.6 0.0 0.061 14.0 0.0 1.9 1 0 0 1 1 1 0 DNA repair REX1-B AP3D1 PF06375.11 KFP23033.1 - 0.032 14.5 11.3 0.62 10.3 0.4 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Cnd1 PF12717.7 KFP23033.1 - 0.09 12.8 4.8 2.3 8.2 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KFP23033.1 - 0.16 12.5 0.0 7.3 7.2 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat DTHCT PF08070.11 KFP23033.1 - 0.18 12.5 13.7 0.033 14.9 8.4 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region T3SS_basalb_I PF17001.5 KFP23033.1 - 0.39 11.3 8.5 1 10.0 1.8 3.7 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Joubert PF15392.6 KFP23034.1 - 4.2e-29 102.4 0.3 4.7e-29 102.2 0.3 1.1 1 0 0 1 1 1 1 Joubert syndrome-associated Nucleoporin_N PF08801.11 KFP23039.1 - 2.6e-108 362.5 0.0 3.6e-108 362.1 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KFP23039.1 - 3.8e-21 75.5 6.4 5.5e-21 74.9 6.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal WD40 PF00400.32 KFP23040.1 - 1.4e-17 63.8 15.1 0.0013 19.5 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFP23040.1 - 1.2e-08 35.1 1.4 0.15 12.4 0.0 5.7 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFP23040.1 - 2.2e-05 23.6 0.6 0.011 14.7 0.2 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Herpes_LMP1 PF05297.11 KFP23040.1 - 2.4 7.3 6.7 3.7 6.6 6.7 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TGF_beta PF00019.20 KFP23041.1 - 3.3e-12 47.3 0.5 5.3e-12 46.6 0.5 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain Laminin_G_1 PF00054.23 KFP23043.1 - 1.8e-83 277.3 0.0 6.3e-27 94.4 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_2 PF02210.24 KFP23043.1 - 1.4e-82 274.5 0.1 4.9e-29 101.5 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain fn3 PF00041.21 KFP23043.1 - 2.4e-23 82.3 0.1 3.5e-12 46.5 0.2 2.7 2 0 0 2 2 2 2 Fibronectin type III domain EGF PF00008.27 KFP23043.1 - 5.4e-11 42.6 35.3 1.3e-07 31.8 7.2 3.6 3 0 0 3 3 3 2 EGF-like domain Laminin_G_3 PF13385.6 KFP23043.1 - 2.6e-10 40.7 0.1 0.028 14.6 0.0 3.4 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily hEGF PF12661.7 KFP23043.1 - 1.2e-07 32.1 22.1 0.0001 22.8 3.6 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF Stirrup PF09061.6 KFP23043.1 - 7.6e-07 29.2 0.1 0.014 15.5 0.0 3.3 3 0 0 3 3 3 2 Stirrup Pur_ac_phosph_N PF16656.5 KFP23043.1 - 2.2e-06 28.2 0.0 0.029 14.9 0.1 2.8 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KFP23043.1 - 0.0054 16.6 0.1 0.52 10.3 0.1 2.4 2 0 0 2 2 2 1 Fibronectin-III type domain LIFR_D2 PF17971.1 KFP23045.1 - 1.3e-56 189.7 2.9 1.7e-54 182.9 2.1 2.9 2 0 0 2 2 2 1 Leukemia inhibitory factor receptor D2 domain fn3 PF00041.21 KFP23045.1 - 2.7e-21 75.7 4.8 3.3e-05 24.1 0.0 6.7 6 2 1 7 7 7 4 Fibronectin type III domain IL6Ra-bind PF09240.10 KFP23045.1 - 3.8e-09 36.8 1.8 0.0048 17.3 0.0 3.7 4 0 0 4 4 4 2 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.10 KFP23045.1 - 5.2e-06 26.6 0.3 0.0035 17.5 0.1 2.7 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding LIFR_N PF18207.1 KFP23045.1 - 0.00013 22.3 0.6 0.00013 22.3 0.6 3.1 3 0 0 3 3 3 1 Leukemia inhibitory factor receptor N-terminal domain Pur_ac_phosph_N PF16656.5 KFP23045.1 - 0.004 17.7 0.1 0.004 17.7 0.1 3.0 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain TMEM154 PF15102.6 KFP23045.1 - 0.075 12.9 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 TMEM154 protein family ObR_Ig PF18589.1 KFP23045.1 - 0.76 10.2 6.0 1.8 9.0 0.2 3.4 4 0 0 4 4 4 0 Obesity receptor immunoglobulin like domain LIFR_D2 PF17971.1 KFP23046.1 - 5.8e-19 68.4 7.9 1.2e-18 67.4 4.9 2.6 2 0 0 2 2 2 1 Leukemia inhibitory factor receptor D2 domain fn3 PF00041.21 KFP23046.1 - 1.1e-15 57.7 5.2 0.0003 21.1 0.0 5.5 6 0 0 6 6 6 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KFP23046.1 - 1.8e-05 25.2 0.8 0.00042 20.8 0.1 3.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain RICTOR_N PF14664.6 KFP23047.1 - 6.1e-107 357.9 1.1 1.3e-106 356.8 1.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho PF14665.6 KFP23047.1 - 5.2e-55 184.4 3.0 5.2e-55 184.4 3.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site RasGEF_N_2 PF14663.6 KFP23047.1 - 1.1e-36 125.4 0.5 1.1e-36 125.4 0.5 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KFP23047.1 - 1.6e-31 108.1 4.6 2e-30 104.6 0.8 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KFP23047.1 - 1.7e-31 108.2 2.7 1.3e-29 102.2 0.2 4.5 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 KFP23047.1 - 0.007 16.9 2.6 0.78 10.3 0.1 3.9 3 0 0 3 3 3 1 HEAT-like repeat RVT_1 PF00078.27 KFP23048.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) hSH3 PF14603.6 KFP23049.1 - 3.8e-35 120.2 20.0 1.5e-24 86.2 0.1 6.1 6 0 0 6 6 6 3 Helically-extended SH3 domain SH3_2 PF07653.17 KFP23049.1 - 9.9e-07 28.3 0.5 2.3e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFP23049.1 - 0.00087 18.9 0.3 0.89 9.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain DUF4651 PF15513.6 KFP23049.1 - 0.0068 16.2 0.1 4.3 7.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) MACPF PF01823.19 KFP23052.1 - 1.7e-32 113.2 0.0 3.8e-32 112.1 0.0 1.5 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.18 KFP23052.1 - 4.6e-10 39.5 14.3 1.5e-09 37.9 14.3 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 KFP23052.1 - 7.6e-05 22.9 5.1 7.6e-05 22.9 5.1 2.7 3 0 0 3 3 3 1 Thrombospondin type 1 domain RVT_1 PF00078.27 KFP23053.1 - 0.0014 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4462 PF14692.6 KFP23057.1 - 0.12 11.9 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) 7tm_1 PF00001.21 KFP23058.1 - 6.8e-39 133.8 12.5 8.3e-39 133.5 12.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP23058.1 - 3.8e-10 39.8 15.2 5.7e-10 39.3 15.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx NdhL PF10716.9 KFP23058.1 - 0.028 14.4 0.0 0.028 14.4 0.0 2.5 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Gag_p30 PF02093.16 KFP23059.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein Nbl1_Borealin_N PF10444.9 KFP23059.1 - 0.15 11.7 2.9 0.22 11.2 0.3 2.4 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal TPR_2 PF07719.17 KFP23060.1 - 2.7e-09 36.4 0.0 0.00085 19.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFP23060.1 - 6.6e-07 29.9 1.3 0.035 14.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP23060.1 - 4.5e-05 23.5 1.5 0.0099 16.0 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFP23060.1 - 6.6e-05 23.4 2.4 0.8 10.7 0.2 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFP23060.1 - 0.00014 22.3 0.4 0.017 15.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFP23060.1 - 0.00019 21.0 0.0 0.005 16.5 0.0 2.5 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 KFP23060.1 - 0.0002 21.0 0.0 0.89 9.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFP23060.1 - 0.00067 19.9 0.0 0.11 12.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 KFP23060.1 - 0.0026 16.8 0.2 0.0035 16.4 0.2 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Vasohibin PF14822.6 KFP23060.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Vasohibin Maf_N PF08383.11 KFP23060.1 - 2.6 7.9 4.9 0.54 10.1 0.3 2.3 3 0 0 3 3 3 0 Maf N-terminal region Pkinase PF00069.25 KFP23061.1 - 1.9e-69 234.0 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP23061.1 - 9.8e-38 129.9 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFP23061.1 - 4.4e-13 49.7 0.0 1.7e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KFP23061.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP23061.1 - 0.0026 17.4 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFP23061.1 - 0.0039 16.6 0.1 0.0082 15.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFP23061.1 - 0.055 13.4 0.2 0.15 11.9 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFP23061.1 - 0.091 11.7 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L37e PF01907.19 KFP23062.1 - 4.2e-27 94.1 15.1 7.7e-27 93.2 15.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFP23062.1 - 0.0064 16.5 1.7 0.01 15.8 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KFP23062.1 - 0.23 11.5 1.4 0.32 11.0 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeS PF04060.13 KFP23062.1 - 0.53 10.0 4.0 0.57 9.9 0.7 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster MACPF PF01823.19 KFP23063.1 - 7.7e-38 130.7 0.5 2.1e-37 129.2 0.1 1.7 1 1 1 2 2 2 1 MAC/Perforin domain Kazal_3 PF18434.1 KFP23063.1 - 3.9e-21 74.5 8.0 3.9e-21 74.5 8.0 4.1 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Sushi PF00084.20 KFP23063.1 - 8.2e-18 64.8 7.4 1.9e-11 44.4 0.4 3.5 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) TSP_1 PF00090.19 KFP23063.1 - 1.2e-08 35.1 22.9 2.9e-06 27.4 3.3 5.7 5 0 0 5 5 5 2 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 KFP23063.1 - 3.4e-06 27.2 13.3 3.4e-06 27.2 13.3 4.4 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A MACPF PF01823.19 KFP23064.1 - 1.2e-43 149.7 1.9 4.7e-43 147.7 0.7 2.0 2 0 0 2 2 2 1 MAC/Perforin domain Sushi PF00084.20 KFP23064.1 - 6.3e-19 68.3 3.6 3.4e-10 40.4 1.0 4.9 4 1 0 4 4 4 2 Sushi repeat (SCR repeat) TSP_1 PF00090.19 KFP23064.1 - 1.4e-13 50.8 31.6 2.8e-07 30.7 9.4 5.9 6 0 0 6 6 6 3 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 KFP23064.1 - 3.3e-11 43.2 14.8 3.3e-11 43.2 14.8 4.3 4 1 1 5 5 5 1 Low-density lipoprotein receptor domain class A CoA_trans PF01144.23 KFP23066.1 - 2.8e-124 412.6 2.2 1.3e-75 253.5 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KFP23066.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Latrophilin PF02354.16 KFP23073.1 - 3.3e-152 506.9 13.5 3.3e-152 506.9 13.5 1.6 2 0 0 2 2 2 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.16 KFP23073.1 - 4.1e-85 285.3 5.2 8.2e-85 284.3 5.2 1.5 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.24 KFP23073.1 - 1.3e-68 230.9 17.9 2e-68 230.3 17.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GAIN PF16489.5 KFP23073.1 - 1.2e-53 181.6 4.7 1.9e-53 181.0 4.7 1.3 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain Gal_Lectin PF02140.18 KFP23073.1 - 4.7e-23 81.4 0.7 4.7e-23 81.4 0.7 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.21 KFP23073.1 - 8.3e-16 58.3 7.3 2e-15 57.0 7.3 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HRM PF02793.22 KFP23073.1 - 8e-08 32.5 0.7 2.3e-07 31.0 0.7 1.9 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.11 KFP23073.1 - 0.0007 18.8 11.3 0.0015 17.7 11.3 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Pox_A14 PF05767.12 KFP23073.1 - 4.3 7.5 6.3 4.2 7.6 2.1 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 RVT_1 PF00078.27 KFP23079.1 - 0.025 14.1 0.0 0.053 13.0 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RasGEF PF00617.19 KFP23081.1 - 3.3e-53 180.5 1.2 4.3e-53 180.1 0.3 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFP23081.1 - 3.6e-16 59.3 1.6 7.9e-16 58.2 0.2 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif RNase_H2-Ydr279 PF09468.10 KFP23081.1 - 0.052 13.7 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF4373 PF14297.6 KFP23081.1 - 0.089 13.6 1.3 33 5.4 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4373) DUF1664 PF07889.12 KFP23081.1 - 0.3 11.1 1.1 0.61 10.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 KFP23083.1 - 7e-72 242.0 0.3 2.6e-69 233.5 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain cNMP_binding PF00027.29 KFP23083.1 - 1.1e-37 128.0 0.1 5.5e-20 71.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KFP23083.1 - 1.2e-33 116.6 0.0 1.2e-32 113.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFP23083.1 - 0.00067 19.1 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Corona_S2 PF01601.16 KFP23083.1 - 0.0037 15.8 0.4 0.006 15.1 0.4 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein ATG16 PF08614.11 KFP23083.1 - 0.0041 17.4 7.7 0.0041 17.4 7.7 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Antigen_Bd37 PF11641.8 KFP23083.1 - 0.022 14.3 0.1 0.022 14.3 0.1 1.8 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein APH PF01636.23 KFP23083.1 - 0.073 13.0 0.5 0.21 11.5 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF3552 PF12072.8 KFP23083.1 - 0.087 12.2 7.3 0.19 11.2 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YlqD PF11068.8 KFP23083.1 - 0.18 12.2 8.7 0.2 12.0 6.3 2.3 2 0 0 2 2 2 0 YlqD protein ADIP PF11559.8 KFP23083.1 - 0.22 11.6 10.8 0.047 13.8 6.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KFP23083.1 - 0.88 10.2 6.3 3.4 8.3 6.3 2.0 1 1 0 1 1 1 0 SlyX PKcGMP_CC PF16808.5 KFP23083.1 - 0.98 9.3 7.1 1.6 8.7 0.2 2.7 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4200 PF13863.6 KFP23083.1 - 1 9.8 10.4 1.2 9.5 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 KFP23083.1 - 7.1 7.2 8.7 3.8 8.0 3.8 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 RRM_1 PF00076.22 KFP23084.1 - 2.1e-36 123.5 0.4 2.6e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP23084.1 - 9e-18 64.2 1.2 4.2e-08 33.2 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFP23084.1 - 4.1e-07 30.0 0.5 0.0074 16.3 0.1 2.7 2 1 0 2 2 2 2 RNA binding motif NID PF07292.13 KFP23084.1 - 0.00036 21.1 0.5 0.012 16.2 0.0 2.5 2 1 0 2 2 2 1 Nmi/IFP 35 domain (NID) Nup35_RRM_2 PF14605.6 KFP23084.1 - 0.00096 19.1 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2076 PF09849.9 KFP23084.1 - 2 8.4 6.0 2.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRM_1 PF00076.22 KFP23085.1 - 2.7e-34 116.8 0.1 2.5e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFP23085.1 - 1.9e-18 66.4 0.1 8.1e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFP23085.1 - 9e-05 22.4 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFP23085.1 - 0.00023 21.2 0.2 0.048 13.7 0.1 2.7 2 2 0 2 2 2 2 RNA binding motif RL PF17797.1 KFP23085.1 - 0.039 13.9 0.0 5.2 7.1 0.0 2.6 2 1 0 2 2 2 0 RL domain Hydrolase PF00702.26 KFP23086.1 - 0.0027 18.0 0.0 0.0031 17.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP23086.1 - 0.04 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Frag1 PF10277.9 KFP23087.1 - 8e-44 149.8 7.2 9.3e-44 149.6 7.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFP23087.1 - 0.0064 16.1 5.2 0.0064 16.1 5.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF4462 PF14692.6 KFP23088.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) FA_desaturase PF00487.24 KFP23089.1 - 2.5e-17 63.6 11.8 3.1e-17 63.2 11.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Tnp_P_element PF12017.8 KFP23090.1 - 3.6e-09 36.4 0.0 7.3e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Transposase protein TCR PF03638.15 KFP23091.1 - 1.6e-22 79.5 59.0 8.9e-13 48.3 22.9 2.7 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KFP23091.1 - 0.11 12.6 45.0 0.35 11.0 17.1 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 CSN4_RPN5_eIF3a PF18420.1 KFP23093.1 - 3.1e-25 88.0 3.7 8.3e-25 86.7 3.7 1.8 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain PCI PF01399.27 KFP23093.1 - 3e-18 66.3 2.7 9.4e-18 64.7 0.0 2.7 3 1 1 4 4 4 1 PCI domain RPN7 PF10602.9 KFP23093.1 - 0.0039 16.9 1.1 0.0069 16.1 1.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 KFP23093.1 - 0.015 15.6 1.1 0.9 9.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFP23093.1 - 0.027 14.5 1.1 3.2 8.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFP23093.1 - 0.23 11.7 1.9 3 8.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YabA PF06156.13 KFP23093.1 - 2.7 8.7 7.8 13 6.5 0.1 3.5 3 1 1 4 4 4 0 Initiation control protein YabA TPR_14 PF13428.6 KFP23093.1 - 5.7 8.0 7.5 3.2 8.8 0.1 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KFP23096.1 - 1.9e-65 220.8 0.0 2.4e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP23096.1 - 2.8e-31 108.7 0.1 3.9e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFP23096.1 - 1.5e-07 31.0 0.2 2.2e-07 30.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFP23096.1 - 5.3e-05 22.7 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFP23096.1 - 0.00027 20.6 0.3 0.00049 19.8 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFP23096.1 - 0.0005 20.1 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFP23096.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KFP23096.1 - 0.078 11.9 0.8 0.18 10.7 0.8 1.6 1 1 0 1 1 1 0 Haspin like kinase domain SH2 PF00017.24 KFP23097.1 - 1.3e-14 54.0 0.1 3.8e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 SH2 domain RasGEF PF00617.19 KFP23097.1 - 9.9e-12 45.4 0.0 2.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Fcf2 PF08698.11 KFP23098.1 - 3.9e-38 129.8 0.5 3.9e-38 129.8 0.5 3.5 4 0 0 4 4 4 1 Fcf2 pre-rRNA processing Aldo_ket_red PF00248.21 KFP23099.1 - 1.4e-05 24.4 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Steroid_dh PF02544.16 KFP23100.1 - 3.9e-26 91.8 5.7 7.3e-26 91.0 5.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase RhoGAP PF00620.27 KFP23101.1 - 4.9e-50 169.3 0.4 4.9e-50 169.3 0.4 2.2 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 KFP23101.1 - 1.2e-06 28.2 9.9 2.9e-06 27.1 9.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PIN_5 PF08745.11 KFP23101.1 - 0.054 12.9 3.6 4.1 6.8 0.3 3.2 3 0 0 3 3 3 0 PINc domain ribonuclease Exonuc_VII_L PF02601.15 KFP23101.1 - 1.2 8.6 10.7 2.8 7.4 10.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit BPL_N PF09825.9 KFP23101.1 - 5.4 6.0 9.2 13 4.7 9.2 1.6 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal zf-RING-like PF08746.11 KFP23101.1 - 7.9 6.9 10.4 20 5.6 10.4 1.7 1 0 0 1 1 1 0 RING-like domain ABC_membrane_2 PF06472.15 KFP23102.1 - 1.1e-96 323.4 6.8 1.5e-96 323.0 6.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFP23102.1 - 5.1e-18 65.9 0.0 1.2e-17 64.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KFP23102.1 - 0.00047 20.7 0.0 0.0017 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KFP23102.1 - 0.0016 17.9 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFP23102.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFP23102.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFP23102.1 - 0.03 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 KFP23102.1 - 0.051 13.2 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Lon_2 PF13337.6 KFP23102.1 - 0.075 11.6 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_16 PF13191.6 KFP23102.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFP23102.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFP23102.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4462 PF14692.6 KFP23103.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Interfer-bind PF09294.10 KFP23104.1 - 8.7e-20 71.0 0.6 4.8e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.17 KFP23104.1 - 1e-17 63.9 0.7 1e-17 63.9 0.7 1.6 2 0 0 2 2 2 1 Tissue factor ECSCR PF15820.5 KFP23104.1 - 0.068 13.0 0.4 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Cadherin_C_2 PF16492.5 KFP23104.1 - 1.5 9.6 3.7 0.82 10.5 1.0 1.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Calponin PF00402.18 KFP23105.1 - 1.9e-44 148.9 16.5 4.8e-16 58.1 1.5 3.5 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.31 KFP23105.1 - 8.8e-23 80.6 0.1 1.3e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Raf1_HTH PF18579.1 KFP23105.1 - 0.14 11.8 0.0 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain CAMSAP_CH PF11971.8 KFP23105.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Alg14 PF08660.11 KFP23106.1 - 8e-64 214.8 0.1 8.9e-64 214.6 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TRAM_LAG1_CLN8 PF03798.16 KFP23107.1 - 3.7e-36 124.7 15.2 3.7e-36 124.7 15.2 1.5 2 0 0 2 2 2 1 TLC domain HXXEE PF13787.6 KFP23107.1 - 0.46 11.3 0.3 0.46 11.3 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF3007 PF11460.8 KFP23107.1 - 4.3 7.7 5.6 5.8 7.2 1.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3007) Cyto_heme_lyase PF01265.17 KFP23108.1 - 4.6e-71 239.8 17.9 5.2e-70 236.3 17.9 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase TDA11 PF17084.5 KFP23108.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 RWD PF05773.22 KFP23109.1 - 1.4e-13 51.1 0.2 3.1e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.12 KFP23109.1 - 1.5e-06 28.3 1.0 0.00031 20.9 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RRM_5 PF13893.6 KFP23111.1 - 4.5e-53 178.1 2.2 6e-39 132.5 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KFP23111.1 - 1.3e-32 111.4 0.3 1.9e-08 34.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFP23111.1 - 1.7e-16 60.2 0.0 2.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KFP23111.1 - 3.4e-10 39.6 0.2 0.018 14.9 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif Cys_Met_Meta_PP PF01053.20 KFP23111.1 - 0.031 12.8 0.1 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Abhydrolase_3 PF07859.13 KFP23111.1 - 0.094 12.6 0.8 0.15 11.9 0.2 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DHO_dh PF01180.21 KFP23112.1 - 1.9e-33 116.0 0.0 3.1e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 KFP23112.1 - 1.6e-28 98.7 0.8 1.6e-28 98.7 0.8 2.4 3 0 0 3 3 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 KFP23112.1 - 1.6e-23 82.5 11.0 1.6e-23 82.5 11.0 3.5 3 1 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 KFP23112.1 - 9.3e-13 48.1 0.0 2.3e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFP23112.1 - 3.1e-08 33.7 0.0 7.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Dus PF01207.17 KFP23112.1 - 3.2e-06 26.4 0.0 2.5e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyr_redox_3 PF13738.6 KFP23112.1 - 3.7e-06 26.4 0.0 0.022 14.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFP23112.1 - 4.1e-05 24.1 0.0 0.6 10.7 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KFP23112.1 - 4.1e-05 24.1 10.3 4.1e-05 24.1 10.3 3.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFP23112.1 - 0.00012 22.1 24.3 0.00036 20.6 9.9 3.0 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFP23112.1 - 0.00042 20.3 2.2 0.00042 20.3 2.2 4.5 4 1 1 5 5 4 1 4Fe-4S binding domain Fer4_2 PF12797.7 KFP23112.1 - 0.0028 17.6 2.3 0.0028 17.6 2.3 4.7 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_9 PF13187.6 KFP23112.1 - 0.0046 17.1 24.4 0.0047 17.1 11.8 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KFP23112.1 - 0.0065 16.2 4.6 0.0065 16.2 4.6 4.9 5 0 0 5 5 5 2 4Fe-4S binding domain Thi4 PF01946.17 KFP23112.1 - 0.042 13.1 0.0 0.099 11.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFP23112.1 - 0.14 11.8 0.0 0.4 10.2 0.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFP23112.1 - 0.21 11.7 0.0 27 4.8 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase MCRA PF06100.11 KFP23112.1 - 0.29 9.9 0.0 0.52 9.0 0.0 1.3 1 0 0 1 1 1 0 MCRA family Fer4_17 PF13534.6 KFP23112.1 - 0.88 10.2 22.0 0.47 11.0 0.8 4.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain DUF4462 PF14692.6 KFP23113.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) PX PF00787.24 KFP23115.1 - 3.2e-26 91.5 0.8 6.7e-26 90.5 0.8 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFP23115.1 - 0.00017 21.2 6.6 0.0043 16.6 0.2 2.5 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.18 KFP23115.1 - 0.032 13.9 3.1 0.13 11.9 3.1 1.8 1 1 0 1 1 1 0 BAR domain FAM184 PF15665.5 KFP23115.1 - 0.14 12.0 2.3 8 6.2 0.0 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B NuA4 PF09340.10 KFP23115.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.4 2 1 1 3 3 3 0 Histone acetyltransferase subunit NuA4 Muted PF14942.6 KFP23115.1 - 0.28 11.5 4.2 9.1 6.6 0.1 2.8 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein PAP2 PF01569.21 KFP23117.1 - 3e-22 78.8 2.9 4e-22 78.4 2.9 1.2 1 0 0 1 1 1 1 PAP2 superfamily Tim17 PF02466.19 KFP23117.1 - 0.093 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MtrF PF09472.10 KFP23117.1 - 0.19 11.1 0.8 0.41 10.1 0.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PAP2 PF01569.21 KFP23118.1 - 2.5e-17 62.9 1.3 3.9e-17 62.3 1.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFP23118.1 - 0.071 12.8 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 PAP2 superfamily Paralemmin PF03285.15 KFP23119.1 - 4.5e-55 187.4 19.8 6.2e-54 183.7 19.8 2.3 1 1 0 1 1 1 1 Paralemmin Mu-like_Pro PF10123.9 KFP23119.1 - 0.041 13.5 7.3 0.083 12.4 7.3 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein PilJ PF13675.6 KFP23119.1 - 0.1 12.7 1.0 0.26 11.3 1.0 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term SNAD2 PF18745.1 KFP23119.1 - 1.1 8.9 5.4 0.51 10.0 0.1 2.7 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 2 ADK PF00406.22 KFP23119.1 - 1.6 8.9 4.4 2.7 8.1 3.5 1.8 2 0 0 2 2 2 0 Adenylate kinase Syntaxin-6_N PF09177.11 KFP23119.1 - 4.4 7.9 12.1 5.1 7.7 8.9 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 KFP23119.1 - 5.2 4.8 8.3 9.6 4.0 8.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reeler PF02014.16 KFP23120.1 - 8.4e-30 104.2 0.0 1.5e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.17 KFP23120.1 - 9.9e-19 67.8 0.0 1.9e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KFP23120.1 - 2e-05 24.8 8.6 4.2e-05 23.7 8.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 KFP23120.1 - 0.086 12.8 6.1 0.18 11.7 5.2 1.9 1 1 1 2 2 2 0 Tight junction protein, Claudin-like hDGE_amylase PF14701.6 KFP23121.1 - 4.7e-165 550.0 0.1 6.2e-165 549.6 0.1 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KFP23121.1 - 9.1e-138 459.3 0.0 1.4e-137 458.7 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KFP23121.1 - 7.2e-78 261.7 0.0 1.1e-77 261.1 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KFP23121.1 - 8.1e-21 74.0 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KFP23121.1 - 1.3e-05 25.0 0.1 5.6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Nuc_sug_transp PF04142.15 KFP23122.1 - 1.7e-138 461.1 18.7 1.9e-138 460.9 18.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFP23122.1 - 3.1e-06 27.4 30.1 7.4e-05 22.9 2.8 2.6 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KFP23122.1 - 5.1e-06 25.9 9.9 5.1e-06 25.9 9.9 2.2 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KFP23122.1 - 2.5e-05 23.4 2.4 2.5e-05 23.4 2.4 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 KFP23122.1 - 0.00015 21.5 8.7 0.00023 20.8 1.4 2.3 2 0 0 2 2 2 2 Putative multidrug resistance efflux transporter UAA PF08449.11 KFP23122.1 - 0.00023 20.5 15.0 0.00028 20.2 13.9 1.6 1 1 0 1 1 1 1 UAA transporter family DUF202 PF02656.15 KFP23122.1 - 0.031 14.7 0.7 0.031 14.7 0.7 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 KFP23123.1 - 2.3e-29 102.4 38.5 1.2e-27 96.8 35.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFP23123.1 - 1.2e-07 30.9 19.3 2.1e-06 26.9 16.0 3.3 1 1 1 2 2 2 1 MFS_1 like family TRM13 PF05206.14 KFP23124.1 - 6.5e-90 301.2 2.5 9.1e-90 300.7 2.5 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 KFP23124.1 - 7.8e-12 44.8 2.0 1.7e-11 43.8 2.0 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger LRR_8 PF13855.6 KFP23125.1 - 4e-29 100.2 14.7 1.7e-09 37.3 1.1 3.7 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KFP23125.1 - 3.2e-26 90.9 40.7 1.2e-05 25.6 3.8 5.4 2 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFP23125.1 - 5.2e-07 29.3 14.9 11 7.1 0.0 8.5 7 1 1 8 8 8 2 Leucine Rich Repeat SPATA19 PF15212.6 KFP23125.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial CREPT PF16566.5 KFP23125.1 - 0.22 11.7 7.4 5.6 7.1 0.1 4.4 2 1 3 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour 2-oxoacid_dh PF00198.23 KFP23126.1 - 1.6e-80 269.9 0.0 2.4e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFP23126.1 - 1.9e-19 69.3 0.1 3.5e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFP23126.1 - 3.6e-15 56.0 0.0 8.4e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain RTC PF01137.21 KFP23128.1 - 9.2e-67 224.5 0.1 1e-66 224.3 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KFP23128.1 - 1.8e-24 86.2 0.1 2.8e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ig_3 PF13927.6 KFP23129.1 - 4.6e-45 152.1 7.8 2.1e-14 53.8 0.1 5.2 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KFP23129.1 - 5.8e-41 138.5 2.9 4.1e-15 55.6 0.2 4.8 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KFP23129.1 - 6.7e-33 112.9 4.8 1.4e-10 41.3 0.0 5.2 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KFP23129.1 - 7.3e-32 109.4 4.2 4.7e-11 42.7 0.1 5.5 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 KFP23129.1 - 1.3e-17 63.9 9.8 0.002 18.3 0.0 8.4 5 4 2 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP23129.1 - 2e-10 40.6 5.6 0.1 12.7 0.0 5.0 5 1 0 5 5 4 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KFP23129.1 - 2.5e-10 40.6 0.8 0.0023 18.3 0.0 4.0 4 0 0 4 4 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set PF05790.15 KFP23129.1 - 4.6e-10 39.5 4.1 6.9e-08 32.6 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Ig_4 PF16680.5 KFP23129.1 - 6.8e-07 29.5 4.4 0.05 13.9 0.0 4.2 4 1 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain DUF2808 PF10989.8 KFP23129.1 - 1.5e-05 25.0 0.7 0.27 11.2 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2808) Receptor_2B4 PF11465.8 KFP23129.1 - 0.00013 22.1 1.6 0.37 11.0 0.0 3.9 3 1 0 3 3 3 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 KFP23129.1 - 0.00019 21.0 0.0 1.4 8.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Herpes_gE PF02480.16 KFP23129.1 - 0.00079 18.3 2.7 0.025 13.3 0.1 3.0 2 1 2 4 4 4 1 Alphaherpesvirus glycoprotein E Ig_C17orf99 PF17736.1 KFP23129.1 - 0.0011 19.0 1.6 0.0045 17.0 0.0 2.9 4 0 0 4 4 3 1 C17orf99 Ig domain Izumo-Ig PF16706.5 KFP23129.1 - 0.0024 17.9 0.1 2.9 8.0 0.0 3.7 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain C1-set PF07654.15 KFP23129.1 - 0.0027 18.0 2.7 2.2 8.7 0.0 4.8 4 2 1 5 5 4 1 Immunoglobulin C1-set domain ICAM_N PF03921.14 KFP23129.1 - 0.042 13.5 5.0 6.1 6.6 0.3 4.0 4 1 0 4 4 4 0 Intercellular adhesion molecule (ICAM), N-terminal domain Syndecan PF01034.20 KFP23129.1 - 0.11 12.5 0.3 4 7.4 0.3 2.4 2 0 0 2 2 2 0 Syndecan domain MBF2 PF15868.5 KFP23129.1 - 0.14 12.7 0.1 1.3 9.6 0.0 2.6 2 1 0 2 2 2 0 Transcription activator MBF2 Adeno_E3_CR1 PF02440.15 KFP23129.1 - 0.29 10.9 1.8 6.6 6.6 0.0 3.5 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 DSPn PF14671.6 KFP23130.1 - 3e-61 206.0 2.2 1.1e-60 204.2 1.2 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFP23130.1 - 1.6e-14 53.8 0.1 6e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFP23130.1 - 2.1e-06 28.0 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KFP23130.1 - 5.4e-05 22.9 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFP23130.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_transf_64 PF09258.10 KFP23131.1 - 5.6e-87 291.1 0.0 6.6e-87 290.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 KFP23131.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFP23131.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cation_efflux PF01545.21 KFP23132.1 - 9.7e-42 143.0 7.8 1.2e-41 142.6 7.8 1.1 1 0 0 1 1 1 1 Cation efflux family ArsP_1 PF03773.13 KFP23132.1 - 0.01 15.0 0.2 0.017 14.3 0.2 1.3 1 0 0 1 1 1 0 Predicted permease TP_methylase PF00590.20 KFP23133.1 - 3.9e-12 46.5 0.0 2.4e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Aldo_ket_red PF00248.21 KFP23134.1 - 1.8e-55 188.2 0.0 1.4e-43 149.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family OLF PF02191.16 KFP23135.1 - 6.2e-83 278.2 9.1 8.3e-83 277.7 9.1 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.8 KFP23135.1 - 1.1e-40 137.6 1.9 2e-39 133.6 0.2 2.5 3 0 0 3 3 3 1 Neurogenesis glycoprotein Snapin_Pallidin PF14712.6 KFP23135.1 - 1.4 9.4 4.6 7.1 7.1 0.1 2.9 3 0 0 3 3 3 0 Snapin/Pallidin Collagen PF01391.18 KFP23137.1 - 1.2e-163 531.0 700.2 6.1e-09 35.5 21.4 22.6 3 1 12 15 15 15 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KFP23137.1 - 2.1e-98 328.3 0.1 2.8e-98 327.9 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KFP23137.1 - 4.8e-05 23.9 0.0 8.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KFP23137.1 - 0.00028 21.0 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 KFP23137.1 - 0.0029 17.8 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain RRM_1 PF00076.22 KFP23138.1 - 2.5e-11 43.2 0.3 8.6e-07 28.7 0.3 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha-amylase_C PF02806.18 KFP23139.1 - 5.5e-15 55.6 0.1 1.2e-14 54.5 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFP23139.1 - 8.3e-14 51.9 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KFP23140.1 - 8.9e-17 61.4 0.3 1.9e-16 60.3 0.3 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KFP23140.1 - 2.7e-12 46.9 0.0 5.2e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Aldolase_II PF00596.21 KFP23143.1 - 4.8e-47 160.3 0.0 5.7e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Syja_N PF02383.18 KFP23143.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain 2-oxoacid_dh PF00198.23 KFP23144.1 - 1.3e-75 253.9 0.1 1.7e-75 253.4 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFP23144.1 - 7.8e-21 73.7 0.4 2.1e-20 72.3 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFP23144.1 - 9e-11 41.9 0.0 3e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFP23144.1 - 6.1e-05 22.8 0.0 0.012 15.4 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like CIDE-N PF02017.15 KFP23144.1 - 0.088 12.8 0.4 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 CIDE-N domain Xlink PF00193.17 KFP23145.1 - 1.9e-20 73.0 0.5 4.6e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 Extracellular link domain LYRIC PF15686.5 KFP23145.1 - 0.01 15.4 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Trypsin PF00089.26 KFP23146.1 - 2.5e-37 128.8 0.0 3.4e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KFP23146.1 - 7.6e-25 87.4 0.2 1.9e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 CUB domain Sushi PF00084.20 KFP23146.1 - 5.6e-17 62.1 2.3 5.2e-08 33.4 0.2 3.1 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) EGF PF00008.27 KFP23146.1 - 1.3e-08 35.0 5.1 1.3e-08 35.0 5.1 3.8 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 KFP23146.1 - 0.0001 22.7 0.9 0.0001 22.7 0.9 4.2 2 0 0 2 2 2 1 Human growth factor-like EGF DUF1986 PF09342.11 KFP23146.1 - 0.0026 18.1 0.6 0.0087 16.4 0.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.18 KFP23147.1 - 8.6e-34 115.5 43.0 6.6e-12 45.4 9.5 3.4 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A PspB PF06667.12 KFP23147.1 - 0.067 13.3 0.8 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 Phage shock protein B COMM_domain PF07258.14 KFP23148.1 - 2.5e-25 88.4 0.0 6.6e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 COMM domain HbrB PF08539.11 KFP23149.1 - 3.7e-11 43.3 0.6 1.6e-08 34.7 0.1 2.5 1 1 1 2 2 2 2 HbrB-like zf-TRAF PF02176.18 KFP23150.1 - 1.3e-21 77.0 37.9 3e-18 66.3 3.2 3.8 3 1 1 4 4 3 3 TRAF-type zinc finger TRAF6_Z2 PF18048.1 KFP23150.1 - 8.1e-18 64.2 6.0 8.1e-18 64.2 6.0 4.7 5 0 0 5 5 4 1 TNF receptor-associated factor 6 zinc finger 2 zf-C3HC4_2 PF13923.6 KFP23150.1 - 1.6e-09 37.4 5.2 1.6e-09 37.4 5.2 4.0 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP23150.1 - 1.5e-08 34.4 4.5 1.5e-08 34.4 4.5 4.2 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFP23150.1 - 2.9e-07 30.2 4.2 2.9e-07 30.2 4.2 3.7 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFP23150.1 - 4e-07 30.3 4.1 4e-07 30.3 4.1 3.8 2 1 2 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KFP23150.1 - 2.3e-06 27.5 6.1 2.3e-06 27.5 6.1 2.8 3 1 0 3 3 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KFP23150.1 - 3.5e-06 27.1 3.7 3.5e-06 27.1 3.7 3.8 2 1 2 4 4 3 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 KFP23150.1 - 4.3e-06 27.1 3.2 4.3e-06 27.1 3.2 3.6 2 2 3 5 5 3 1 TRAF-like zinc-finger SlyX PF04102.12 KFP23150.1 - 0.00048 20.7 2.6 0.00048 20.7 2.6 2.1 2 0 0 2 2 1 1 SlyX PspA_IM30 PF04012.12 KFP23150.1 - 0.00078 19.1 2.2 0.0022 17.6 2.2 1.8 1 0 0 1 1 1 1 PspA/IM30 family zf-RING_5 PF14634.6 KFP23150.1 - 0.00084 19.2 5.0 0.00084 19.2 5.0 4.1 2 2 2 4 4 2 1 zinc-RING finger domain Med21 PF11221.8 KFP23150.1 - 0.0026 18.0 2.3 0.0054 17.0 2.3 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TSC22 PF01166.18 KFP23150.1 - 0.014 15.7 2.4 3.9 7.8 0.3 3.0 1 1 2 3 3 3 0 TSC-22/dip/bun family Prok-RING_4 PF14447.6 KFP23150.1 - 0.015 15.1 4.4 0.015 15.1 4.4 3.8 2 2 1 3 3 2 0 Prokaryotic RING finger family 4 Tropomyosin_1 PF12718.7 KFP23150.1 - 0.016 15.3 1.8 0.031 14.4 1.8 1.3 1 0 0 1 1 1 0 Tropomyosin like CENP-F_leu_zip PF10473.9 KFP23150.1 - 0.019 15.0 0.8 0.054 13.5 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_11 PF17123.5 KFP23150.1 - 0.023 14.5 2.9 0.077 12.8 2.9 2.0 1 0 0 1 1 1 0 RING-like zinc finger Sina PF03145.16 KFP23150.1 - 0.026 14.5 25.9 0.091 12.7 7.1 4.0 2 1 2 4 4 4 0 Seven in absentia protein family Spc7 PF08317.11 KFP23150.1 - 0.044 12.7 0.2 0.077 11.9 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 KFP23150.1 - 0.05 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 U-box PF04564.15 KFP23150.1 - 0.055 13.6 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 1 0 U-box domain zf-RAG1 PF10426.9 KFP23150.1 - 0.059 13.5 1.2 0.37 11.0 0.1 3.0 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain HMMR_N PF15905.5 KFP23150.1 - 0.061 12.8 0.3 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Myosin_tail_1 PF01576.19 KFP23150.1 - 0.072 10.9 0.8 0.1 10.4 0.8 1.1 1 0 0 1 1 1 0 Myosin tail DUF1664 PF07889.12 KFP23150.1 - 0.074 13.1 0.9 0.17 11.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 KFP23150.1 - 0.076 12.4 1.7 0.13 11.7 1.7 1.2 1 0 0 1 1 1 0 Tropomyosin UPF0242 PF06785.11 KFP23150.1 - 0.087 12.9 1.4 0.19 11.8 1.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KFP23150.1 - 0.13 12.3 1.4 0.26 11.3 1.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KFP23150.1 - 0.13 12.3 2.5 0.3 11.2 2.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 KFP23150.1 - 0.14 12.6 2.9 0.25 11.8 1.6 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 zf-C2H2_4 PF13894.6 KFP23150.1 - 0.43 11.6 0.2 0.43 11.6 0.2 5.8 6 0 0 6 6 4 0 C2H2-type zinc finger PKcGMP_CC PF16808.5 KFP23150.1 - 0.53 10.2 2.7 1.7 8.6 0.5 2.6 1 1 2 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TACC_C PF05010.14 KFP23150.1 - 1 9.1 7.2 0.048 13.5 1.2 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DM PF00751.18 KFP23150.1 - 1.1 9.2 18.2 1.8 8.6 4.8 3.3 1 1 2 3 3 3 0 DM DNA binding domain Cortex-I_coil PF09304.10 KFP23150.1 - 2 8.7 4.9 0.85 9.9 1.0 2.3 3 0 0 3 3 2 0 Cortexillin I, coiled coil RAG1 PF12940.7 KFP23152.1 - 0 1247.3 0.9 0 1246.8 0.9 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1), recombinase RAG1_imp_bd PF12560.8 KFP23152.1 - 9.5e-118 392.9 15.7 9.5e-118 392.9 15.7 2.1 2 0 0 2 2 2 1 RAG1 importin binding zf-RAG1 PF10426.9 KFP23152.1 - 3.2e-18 65.5 10.7 3.3e-17 62.3 2.1 2.7 2 0 0 2 2 2 2 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.25 KFP23152.1 - 6.3e-07 29.2 14.6 6.3e-07 29.2 14.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFP23152.1 - 0.00012 21.8 13.7 0.00012 21.8 13.7 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFP23152.1 - 0.00025 20.8 8.7 0.00025 20.8 8.7 2.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFP23152.1 - 0.013 15.7 13.4 0.013 15.7 13.4 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING RAG2 PF03089.14 KFP23153.1 - 3.8e-187 621.2 0.1 4.9e-187 620.9 0.1 1.1 1 0 0 1 1 1 1 Recombination activating protein 2 RAG2_PHD PF13341.6 KFP23153.1 - 7.8e-48 160.4 2.0 1.6e-47 159.4 2.0 1.6 1 0 0 1 1 1 1 RAG2 PHD domain Kelch_3 PF13415.6 KFP23153.1 - 4.4e-08 33.2 0.0 0.0013 18.9 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KFP23153.1 - 4.4e-05 23.4 0.7 9.1 6.4 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KFP23153.1 - 0.00021 21.2 1.6 2.9 8.0 0.0 3.8 4 0 0 4 4 4 2 Kelch motif PHD PF00628.29 KFP23153.1 - 0.0039 17.1 1.0 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 PHD-finger Kelch_6 PF13964.6 KFP23153.1 - 0.02 15.2 0.1 2.2 8.7 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.25 KFP23153.1 - 0.14 11.8 0.2 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Kelch motif DUF5567 PF17722.1 KFP23154.1 - 1.4e-50 172.3 0.1 1.6e-50 172.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5567) API5 PF05918.11 KFP23164.1 - 4.6e-196 652.7 0.0 5.2e-196 652.5 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KFP23164.1 - 9e-05 22.8 0.1 0.00035 20.9 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats MMS19_N PF14500.6 KFP23164.1 - 0.012 15.2 1.9 0.11 12.0 1.9 2.3 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Dak2 PF02734.17 KFP23164.1 - 0.024 14.5 0.0 0.072 13.0 0.0 1.7 1 1 0 1 1 1 0 DAK2 domain DUF1319 PF07028.11 KFP23164.1 - 0.073 13.3 0.3 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) TPR_2 PF07719.17 KFP23165.1 - 3.5e-22 76.7 5.0 0.00076 19.4 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFP23165.1 - 1.4e-21 75.3 6.8 0.00029 20.5 0.1 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP23165.1 - 4.7e-13 48.2 3.2 0.014 15.5 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFP23165.1 - 8.1e-12 44.3 7.6 0.032 14.3 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFP23165.1 - 1.2e-11 44.0 0.6 0.097 12.4 0.0 6.4 5 1 1 6 6 6 4 TPR repeat TPR_12 PF13424.6 KFP23165.1 - 1.5e-10 41.2 16.7 0.036 14.3 2.6 6.9 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFP23165.1 - 1.8e-08 34.5 1.5 0.79 10.7 0.0 6.4 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFP23165.1 - 7.7e-06 26.0 0.9 0.099 12.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFP23165.1 - 0.00014 22.3 4.7 1.5 9.4 0.7 4.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFP23165.1 - 0.00019 21.2 13.4 1.2 9.1 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFP23165.1 - 0.00066 20.3 2.5 5.7 7.7 0.6 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP23165.1 - 0.0017 18.6 4.4 0.094 13.0 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KFP23165.1 - 0.0086 16.1 1.4 1.9 8.6 0.1 3.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KFP23165.1 - 0.011 14.8 0.5 0.011 14.8 0.5 2.8 3 2 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) PHM7_ext PF12621.8 KFP23165.1 - 0.065 13.4 0.0 5.5 7.2 0.0 2.6 1 1 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter BSD PF03909.17 KFP23165.1 - 0.075 13.0 0.8 7.2 6.7 0.0 3.2 3 0 0 3 3 3 0 BSD domain E2F_CC-MB PF16421.5 KFP23165.1 - 1.3 9.4 4.8 5.6 7.4 4.8 2.1 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain TPR_17 PF13431.6 KFP23165.1 - 1.9 9.1 17.4 12 6.5 0.2 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 KFP23166.1 - 1e-32 113.9 0.0 1.3e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_64 PF09258.10 KFP23168.1 - 9.9e-99 329.6 0.2 1.5e-98 329.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KFP23168.1 - 2.9e-57 194.2 0.0 3.9e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Tetraspanin PF00335.20 KFP23169.1 - 1.4e-50 172.1 8.6 1.6e-50 172.0 8.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KFP23169.1 - 0.0044 16.8 5.2 0.017 14.9 3.6 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF2981) GATase_5 PF13507.6 KFP23169.1 - 0.0051 15.9 0.1 0.021 14.0 0.0 1.8 1 1 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Tetraspanin PF00335.20 KFP23170.1 - 3.2e-45 154.6 8.3 3.7e-45 154.4 8.3 1.0 1 0 0 1 1 1 1 Tetraspanin family p53-inducible11 PF14936.6 KFP23171.1 - 1.5e-64 217.4 0.1 4.9e-64 215.7 0.1 1.7 1 1 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF4345 PF14248.6 KFP23171.1 - 0.044 13.7 0.2 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) SET PF00856.28 KFP23173.1 - 4.8e-06 27.1 0.4 2.9e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 SET domain zf_PR_Knuckle PF18445.1 KFP23173.1 - 9.7e-05 22.1 1.7 0.00023 20.9 1.7 1.6 1 0 0 1 1 1 1 PR zinc knuckle motif C2 PF00168.30 KFP23174.1 - 1.4e-23 83.1 0.0 3.4e-14 53.0 0.2 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KFP23174.1 - 1.5e-05 24.9 0.3 0.059 13.3 0.0 2.9 2 1 1 3 3 3 2 Phosphoinositide 3-kinase C2 2OG-FeII_Oxy_4 PF13661.6 KFP23174.1 - 0.015 15.9 0.1 0.039 14.6 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Astacin PF01400.24 KFP23175.1 - 3e-59 199.9 0.0 4.8e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB PF00431.20 KFP23175.1 - 2.5e-28 98.6 0.0 7.8e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 CUB domain SH3_9 PF14604.6 KFP23177.1 - 7.7e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP23177.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Wtap PF17098.5 KFP23177.1 - 0.077 12.9 0.6 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family Tropomyosin_1 PF12718.7 KFP23177.1 - 8 6.6 7.9 20 5.3 0.2 3.1 2 1 2 4 4 4 0 Tropomyosin like C1q PF00386.21 KFP23178.1 - 1.4e-71 238.7 1.6 2.2e-38 131.3 0.1 2.1 2 0 0 2 2 2 2 C1q domain BclA_C PF18573.1 KFP23178.1 - 1.1e-06 28.6 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 2 BclA C-terminal domain Rhodanese PF00581.20 KFP23178.1 - 0.00066 20.2 0.0 0.65 10.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF3531 PF12049.8 KFP23178.1 - 0.044 13.7 0.1 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) Complex1_30kDa PF00329.19 KFP23179.1 - 1.5e-43 148.3 0.0 2e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BTB PF00651.31 KFP23180.1 - 2.5e-26 92.1 2.3 4.6e-26 91.2 2.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.6 KFP23180.1 - 1e-17 63.7 5.0 5.2e-06 26.5 0.0 5.2 3 2 2 5 5 5 3 Kelch motif BACK PF07707.15 KFP23180.1 - 5e-10 39.4 0.9 4.6e-08 33.1 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KFP23180.1 - 4e-07 29.7 0.4 0.048 13.6 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KFP23180.1 - 2e-06 27.3 1.0 0.026 14.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KFP23180.1 - 0.00046 20.1 0.4 0.1 12.6 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain DSPc PF00782.20 KFP23181.1 - 2.4e-18 66.2 0.0 2.7e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFP23181.1 - 0.00016 21.3 0.1 0.00016 21.3 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 KFP23181.1 - 0.00073 20.0 0.0 0.00083 19.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase2 PF03162.13 KFP23181.1 - 0.013 15.1 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFP23181.1 - 0.031 14.4 0.0 0.054 13.6 0.0 1.4 2 0 0 2 2 2 0 Inositol hexakisphosphate RRM_1 PF00076.22 KFP23182.1 - 1.5e-51 172.1 0.0 2.3e-18 65.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KFP23182.1 - 7.2e-10 38.8 0.0 0.1 12.7 0.0 3.9 3 2 0 3 3 3 3 RNA binding domain RRM_7 PF16367.5 KFP23182.1 - 0.0002 21.4 0.0 0.75 10.0 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 KFP23182.1 - 0.0034 17.6 5.8 4 7.6 1.3 4.2 3 2 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFP23182.1 - 0.016 15.2 0.0 0.56 10.3 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif AID PF18767.1 KFP23182.1 - 0.074 13.1 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Activation induced deaminase BRAP2 PF07576.12 KFP23182.1 - 0.084 13.1 0.1 4.3 7.6 0.0 2.8 3 0 0 3 3 3 0 BRCA1-associated protein 2 Rapsyn_N PF10579.9 KFP23183.1 - 8.7e-44 147.5 0.2 1e-42 144.1 0.1 2.5 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.28 KFP23183.1 - 4.9e-21 73.6 12.5 0.00016 21.3 0.1 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFP23183.1 - 1.1e-20 73.7 4.9 3.2e-07 30.5 0.0 5.2 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFP23183.1 - 5.2e-16 57.4 11.6 0.0044 17.0 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFP23183.1 - 3.2e-11 42.5 9.3 0.035 14.3 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFP23183.1 - 1.3e-10 40.5 3.6 0.057 13.5 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP23183.1 - 8.2e-08 32.0 2.3 2.4e-06 27.2 0.3 2.8 2 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 KFP23183.1 - 1.1e-06 28.3 1.4 0.0013 18.6 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFP23183.1 - 2.3e-05 24.5 1.8 0.37 10.8 0.0 3.8 3 1 1 4 4 3 2 Domain of Unknown Function (DUF3856) zf-RING_11 PF17123.5 KFP23183.1 - 0.00026 20.7 0.6 0.00026 20.7 0.6 2.9 3 0 0 3 3 2 1 RING-like zinc finger TPR_11 PF13414.6 KFP23183.1 - 0.00042 19.9 0.4 7.8 6.3 0.0 4.9 5 0 0 5 5 5 0 TPR repeat TPR_19 PF14559.6 KFP23183.1 - 0.00048 20.6 0.4 2.5 8.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFP23183.1 - 0.00069 20.2 0.4 27 5.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFP23183.1 - 0.0012 19.5 2.3 2.8 9.0 0.1 5.2 5 2 1 6 6 5 1 Tetratricopeptide repeat SNAP PF14938.6 KFP23183.1 - 0.0014 18.2 0.3 0.74 9.2 0.2 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KFP23183.1 - 0.0022 18.5 4.4 1.7 9.5 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.9 KFP23183.1 - 0.0081 15.9 5.2 1.1 9.0 1.2 3.7 2 1 2 4 4 4 1 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 KFP23183.1 - 0.0089 16.1 4.4 0.38 10.9 0.0 4.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat zf-RING_2 PF13639.6 KFP23183.1 - 0.024 15.0 0.3 0.024 15.0 0.3 3.9 4 0 0 4 4 4 0 Ring finger domain PCYCGC PF13798.6 KFP23183.1 - 0.038 13.8 2.1 0.11 12.4 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function with PCYCGC motif ANAPC5 PF12862.7 KFP23183.1 - 0.087 12.9 1.4 13 5.9 0.6 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 KFP23183.1 - 0.54 10.8 6.2 22 5.7 0.8 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFP23183.1 - 0.78 10.0 9.3 7.4 6.9 0.6 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA PF00004.29 KFP23184.1 - 5.8e-42 143.2 0.0 1.2e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFP23184.1 - 5.8e-20 71.0 0.1 1.2e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFP23184.1 - 2.5e-10 40.0 1.1 4.2e-10 39.3 0.3 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KFP23184.1 - 4.5e-06 26.7 0.1 2e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFP23184.1 - 1.6e-05 25.4 0.3 0.0036 17.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KFP23184.1 - 4.4e-05 23.3 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFP23184.1 - 0.00019 21.6 0.0 0.00064 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFP23184.1 - 0.0005 20.3 0.3 0.083 13.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KFP23184.1 - 0.0029 16.8 0.0 0.0053 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KFP23184.1 - 0.0029 17.8 0.1 0.0064 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KFP23184.1 - 0.0041 16.6 0.1 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KFP23184.1 - 0.0052 16.2 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KFP23184.1 - 0.0097 15.5 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 KFP23184.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KFP23184.1 - 0.038 13.7 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KFP23184.1 - 0.038 13.7 0.2 0.13 12.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KFP23184.1 - 0.054 12.8 0.2 0.18 11.1 0.0 1.9 3 0 0 3 3 3 0 KaiC TIP49 PF06068.13 KFP23184.1 - 0.08 12.1 0.1 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 KFP23184.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFP23184.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFP23184.1 - 0.16 11.5 0.9 1.4 8.5 0.2 2.2 1 1 1 2 2 2 0 AAA domain Claudin_2 PF13903.6 KFP23185.1 - 8.6e-13 48.5 5.1 1e-12 48.2 5.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KFP23185.1 - 0.019 14.8 8.3 0.027 14.3 8.3 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3961 PF13106.6 KFP23185.1 - 0.14 11.8 1.1 0.27 10.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Zip PF02535.22 KFP23186.1 - 3.5e-53 181.0 2.1 5.9e-53 180.2 2.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Ets PF00178.22 KFP23187.1 - 2.1e-23 82.6 2.9 3.5e-23 81.9 2.9 1.4 1 0 0 1 1 1 1 Ets-domain I-set PF07679.16 KFP23188.1 - 8.1e-105 343.1 12.8 5e-17 61.8 0.0 8.9 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP23188.1 - 1.3e-70 234.0 0.4 9.2e-13 48.6 0.0 8.5 8 0 0 8 8 8 8 Immunoglobulin domain ig PF00047.25 KFP23188.1 - 5e-41 138.8 2.3 5.4e-08 32.9 0.0 8.5 8 0 0 8 8 8 8 Immunoglobulin domain fn3 PF00041.21 KFP23188.1 - 7.8e-39 131.9 0.0 6.9e-12 45.5 0.0 4.1 3 0 0 3 3 3 3 Fibronectin type III domain Ig_2 PF13895.6 KFP23188.1 - 1.7e-32 111.6 0.1 3.9e-05 23.9 0.0 8.9 7 2 1 8 8 8 7 Immunoglobulin domain THB PF18362.1 KFP23188.1 - 9.5e-22 76.3 0.1 1.9e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Tri-helix bundle domain V-set PF07686.17 KFP23188.1 - 1.6e-21 76.6 7.8 0.036 14.2 0.0 11.0 7 5 1 8 8 8 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KFP23188.1 - 1.4e-08 34.6 0.2 0.52 10.4 0.0 6.2 5 1 0 5 5 5 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KFP23188.1 - 2.4e-05 24.6 4.9 9.1 6.7 0.0 6.3 5 1 1 6 6 5 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 KFP23188.1 - 0.0014 18.6 1.4 43 4.3 0.0 6.1 7 0 0 7 7 7 0 Izumo-like Immunoglobulin domain PKD_3 PF16820.5 KFP23188.1 - 0.062 13.1 10.2 0.42 10.4 0.1 5.2 6 0 0 6 6 6 0 PKD-like domain DENN PF02141.21 KFP23190.1 - 2.1e-33 115.9 2.1 5.2e-33 114.6 2.1 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFP23190.1 - 8.8e-19 68.0 0.7 2.8e-18 66.4 0.7 2.0 1 0 0 1 1 1 1 uDENN domain zf-C4 PF00105.18 KFP23191.1 - 8.8e-28 96.6 15.5 1.5e-27 95.8 15.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KFP23191.1 - 2.2e-27 96.0 2.0 3.7e-27 95.2 2.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor His_Phos_2 PF00328.22 KFP23192.1 - 6.1e-19 68.6 0.0 7.5e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WD40 PF00400.32 KFP23193.1 - 1e-11 45.1 9.6 0.00011 22.9 0.1 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ArfGap PF01412.18 KFP23195.1 - 0.089 12.9 0.2 0.26 11.4 0.2 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Trypsin PF00089.26 KFP23197.1 - 3.4e-68 229.7 0.0 4.8e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 KFP23197.1 - 7e-43 144.8 12.0 1e-22 80.2 3.7 2.6 2 0 0 2 2 2 2 Kringle domain Thrombin_light PF09396.10 KFP23197.1 - 9.6e-25 86.1 1.7 2.4e-24 84.8 1.7 1.7 1 0 0 1 1 1 1 Thrombin light chain Gla PF00594.20 KFP23197.1 - 5.8e-18 64.8 7.6 1.3e-17 63.7 7.6 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1986 PF09342.11 KFP23197.1 - 6.8e-06 26.5 0.1 1.5e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) RhoGAP PF00620.27 KFP23198.1 - 2.7e-44 150.7 0.3 5.7e-44 149.6 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KFP23198.1 - 4.3e-40 137.1 3.5 4.7e-40 136.9 1.2 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KFP23198.1 - 1.3e-09 38.0 0.2 2.6e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain ATG13 PF10033.9 KFP23199.1 - 3.4e-14 53.1 0.3 7.6e-07 29.1 0.3 3.0 1 1 1 2 2 2 2 Autophagy-related protein 13 DDE_Tnp_4 PF13359.6 KFP23200.1 - 2.7e-37 127.9 0.0 3.8e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KFP23200.1 - 4.3e-06 26.5 0.0 0.0002 21.0 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 KFP23200.1 - 0.00017 21.3 0.1 0.061 13.0 0.0 2.1 1 1 1 2 2 2 2 Transposase DDE domain 7tm_1 PF00001.21 KFP23201.1 - 2.1e-75 253.5 6.1 2.9e-75 253.0 6.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KFP23201.1 - 4.2e-08 33.1 8.9 4.2e-08 33.1 8.9 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KFP23201.1 - 2.2e-06 27.3 16.0 5.8e-06 25.9 6.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP23201.1 - 1.7e-05 24.7 4.6 1.7e-05 24.7 4.6 2.4 2 1 1 3 3 3 1 Olfactory receptor PTN_MK_N PF05196.13 KFP23202.1 - 1.1e-27 95.9 18.1 1.1e-27 95.9 18.1 2.6 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain PTN_MK_C PF01091.18 KFP23202.1 - 1.3e-25 89.6 7.0 1.3e-25 89.6 7.0 2.8 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, C-terminal domain DAGK_acc PF00609.19 KFP23204.1 - 6e-48 163.2 0.0 1.1e-47 162.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KFP23204.1 - 7.2e-29 100.0 0.0 1.7e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.7 KFP23204.1 - 7.9e-13 48.8 0.1 2.1e-12 47.4 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) C1_1 PF00130.22 KFP23204.1 - 2.2e-12 46.7 25.9 3e-10 39.8 14.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_3 PF13606.6 KFP23204.1 - 2e-09 36.9 0.0 0.0006 20.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFP23204.1 - 1.7e-08 34.9 0.0 0.00042 20.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFP23204.1 - 1.5e-07 31.5 0.0 0.0014 18.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFP23204.1 - 0.00052 20.3 0.1 0.11 12.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat zf-C2H2_4 PF13894.6 KFP23204.1 - 8.7 7.5 9.1 42 5.3 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger bZIP_1 PF00170.21 KFP23206.1 - 4.4e-16 58.7 14.5 7.6e-16 58.0 14.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFP23206.1 - 8e-09 35.4 9.4 8e-09 35.4 9.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFP23206.1 - 2.9e-05 24.5 10.1 6.2e-05 23.4 10.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc29 PF17082.5 KFP23206.1 - 0.0095 15.8 0.3 0.016 15.1 0.3 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 LMBR1 PF04791.16 KFP23206.1 - 0.02 13.9 0.1 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tcf25 PF04910.14 KFP23206.1 - 0.041 13.0 0.2 0.058 12.5 0.2 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 HAUS-augmin3 PF14932.6 KFP23206.1 - 0.056 13.0 5.5 0.094 12.3 5.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4337 PF14235.6 KFP23206.1 - 0.075 13.2 0.7 0.13 12.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TPR_MLP1_2 PF07926.12 KFP23206.1 - 0.076 13.1 11.0 0.13 12.4 11.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein JMY PF15871.5 KFP23206.1 - 0.079 12.3 4.8 0.14 11.4 4.8 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein APG6_N PF17675.1 KFP23206.1 - 0.094 13.2 7.7 0.21 12.1 7.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KFP23206.1 - 0.15 12.3 6.7 0.28 11.4 6.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KFP23206.1 - 0.18 11.9 11.5 0.31 11.1 11.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Goodbye PF17109.5 KFP23206.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.1 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF4404 PF14357.6 KFP23206.1 - 0.46 11.1 2.6 0.68 10.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF724 PF05266.14 KFP23206.1 - 0.49 10.2 4.6 0.86 9.4 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3552 PF12072.8 KFP23206.1 - 0.68 9.3 9.2 1.1 8.7 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PHD PF00628.29 KFP23207.1 - 1.7e-12 47.0 6.6 3.6e-12 46.0 6.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFP23207.1 - 0.0034 17.6 0.1 0.014 15.6 0.1 2.0 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.22 KFP23207.1 - 0.0047 16.8 2.0 0.0047 16.8 2.0 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 KFP23207.1 - 0.0082 15.9 1.8 0.024 14.5 1.8 1.8 1 0 0 1 1 1 1 AT hook motif PHD_2 PF13831.6 KFP23207.1 - 0.022 14.3 1.0 0.022 14.3 1.0 1.9 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KFP23207.1 - 0.04 14.1 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KFP23207.1 - 0.21 11.9 7.8 0.4 11.0 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 KFP23207.1 - 0.26 11.4 7.2 1.2 9.3 7.2 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger C1_2 PF03107.16 KFP23207.1 - 0.44 10.9 4.2 0.17 12.3 1.4 1.7 2 0 0 2 2 1 0 C1 domain DUF1043 PF06295.12 KFP23207.1 - 0.74 9.8 14.1 0.039 14.0 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Prok-RING_1 PF14446.6 KFP23207.1 - 1.1 9.2 6.0 1.7 8.6 3.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KFP23207.1 - 1.2 8.8 5.4 1.1 8.9 3.5 1.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFP23207.1 - 1.3 9.4 4.6 2.6 8.4 4.6 1.6 1 0 0 1 1 1 0 RING-like domain DUF1664 PF07889.12 KFP23207.1 - 3.5 7.7 13.1 0.028 14.4 4.2 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) ADK_lid PF05191.14 KFP23207.1 - 5 7.2 8.4 1.1 9.3 3.7 2.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.12 KFP23207.1 - 5.1 7.1 6.0 6.1 6.9 0.2 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DZR PF12773.7 KFP23207.1 - 5.5 7.1 7.2 1.9e+02 2.2 7.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-PHD-like PF15446.6 KFP23207.1 - 6.3 6.4 10.0 0.12 12.0 0.9 2.6 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 KFP23207.1 - 8.5 5.8 6.4 0.51 9.7 0.9 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pex16 PF08610.10 KFP23208.1 - 3.1e-66 223.7 4.3 3.5e-66 223.6 4.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PID PF00640.23 KFP23210.1 - 1.9e-34 118.7 0.3 3.2e-34 117.9 0.3 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.6 KFP23210.1 - 1.6e-14 53.5 0.2 3.2e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFP23210.1 - 2.6e-06 27.0 0.0 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFP23210.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PID_2 PF14719.6 KFP23210.1 - 0.0018 18.2 0.1 0.0031 17.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 KFP23210.1 - 0.13 12.4 0.7 0.42 10.8 0.1 2.1 2 1 0 2 2 2 0 Phosphotyrosine-binding domain FAD_binding_7 PF03441.14 KFP23211.1 - 2.6e-75 252.3 0.1 4.1e-75 251.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFP23211.1 - 2.2e-26 92.8 0.0 5.7e-26 91.5 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase Peripla_BP_6 PF13458.6 KFP23211.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein TPT PF03151.16 KFP23212.1 - 3.3e-19 69.3 1.7 4e-19 69.1 1.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFP23212.1 - 8e-09 35.8 19.3 3.1e-05 24.1 9.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFP23212.1 - 0.0015 17.8 9.5 0.0019 17.4 9.5 1.1 1 0 0 1 1 1 1 UAA transporter family Sulfotransfer_1 PF00685.27 KFP23213.1 - 9.9e-57 192.4 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KFP23213.1 - 2.5e-16 60.7 0.0 1e-10 42.4 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family UPF0444 PF15475.6 KFP23214.1 - 1.7e-45 153.2 13.8 1.9e-45 153.1 13.8 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 UPF0444 PF15475.6 KFP23215.1 - 1.2e-20 73.5 10.1 1.3e-20 73.4 10.1 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 CUB PF00431.20 KFP23217.1 - 3.1e-62 207.8 0.1 1.2e-30 106.1 0.0 2.8 3 0 0 3 3 3 2 CUB domain Astacin PF01400.24 KFP23217.1 - 5.6e-56 189.2 0.0 9e-56 188.5 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CUB_2 PF02408.20 KFP23217.1 - 0.0027 17.4 2.1 0.15 11.8 0.2 2.7 2 0 0 2 2 2 2 CUB-like domain Cytochrome_CBB3 PF13442.6 KFP23218.1 - 4.4 7.7 6.0 0.37 11.2 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III FYVE PF01363.21 KFP23218.1 - 8.9 6.5 25.9 0.18 12.0 11.5 2.5 2 0 0 2 2 2 0 FYVE zinc finger PP1_inhibitor PF05361.12 KFP23219.1 - 9e-15 54.9 1.5 9.5e-15 54.8 1.5 1.0 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Kunitz_BPTI PF00014.23 KFP23220.1 - 8.3e-32 109.2 23.4 3.7e-18 65.5 8.9 3.3 4 0 0 4 4 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MANEC PF07502.14 KFP23220.1 - 5e-28 97.2 2.3 5e-28 97.2 2.3 3.0 4 0 0 4 4 2 1 MANEC domain Ldl_recept_a PF00057.18 KFP23220.1 - 2.3e-08 34.1 12.0 9.6e-08 32.1 12.0 2.2 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Orf78 PF06024.12 KFP23220.1 - 3.1e-05 24.2 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) REJ PF02010.15 KFP23220.1 - 0.0041 16.0 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 REJ domain Stevor PF17410.2 KFP23220.1 - 0.0049 16.5 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF3377 PF11857.8 KFP23220.1 - 0.01 15.7 0.2 0.027 14.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Chordopox_A13L PF05961.11 KFP23220.1 - 0.011 15.9 0.4 0.034 14.4 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Y_Y_Y PF07495.13 KFP23220.1 - 0.014 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Y_Y_Y domain DUF4064 PF13273.6 KFP23220.1 - 0.024 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) PKD PF00801.20 KFP23220.1 - 0.027 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 PKD domain EphA2_TM PF14575.6 KFP23220.1 - 0.091 13.7 0.1 0.27 12.1 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain 4HB_MCP_1 PF12729.7 KFP23220.1 - 0.27 10.7 0.5 0.5 9.9 0.5 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Ras PF00071.22 KFP23221.1 - 2.4e-32 111.7 0.0 2.9e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP23221.1 - 5e-13 49.3 0.0 9.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SNARE PF05739.19 KFP23221.1 - 0.074 13.1 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 SNARE domain Arf PF00025.21 KFP23221.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Ndc80_HEC PF03801.13 KFP23222.1 - 1.4e-46 157.9 0.0 1.1e-45 154.9 0.0 2.5 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 KFP23222.1 - 3.2e-32 110.4 2.8 3.2e-32 110.4 2.8 6.1 5 2 1 6 6 6 1 Domain of unknown function (DUF5595) DUF4164 PF13747.6 KFP23222.1 - 0.0077 16.5 4.2 0.0077 16.5 4.2 4.3 2 2 1 3 3 3 1 Domain of unknown function (DUF4164) bZIP_1 PF00170.21 KFP23222.1 - 0.025 14.7 0.8 0.025 14.7 0.8 5.8 4 2 2 6 6 6 0 bZIP transcription factor HrpB7 PF09486.10 KFP23222.1 - 0.11 12.8 27.8 0.091 13.2 4.9 4.0 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) RBD-FIP PF09457.10 KFP23222.1 - 6.1 6.8 7.8 19 5.3 0.3 3.6 3 0 0 3 3 3 0 FIP domain Hormone_2 PF00123.20 KFP23224.1 - 1.8e-19 69.3 2.6 5.7e-14 51.7 0.5 2.7 3 0 0 3 3 3 2 Peptide hormone Pkinase_Tyr PF07714.17 KFP23225.1 - 6.4e-93 310.8 0.0 8.2e-93 310.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFP23225.1 - 1.1e-45 156.1 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KFP23225.1 - 3.2e-28 97.7 0.2 6.2e-28 96.7 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KFP23225.1 - 7.3e-20 70.3 0.4 3.3e-19 68.2 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFP23225.1 - 6.3e-15 54.8 0.0 1.9e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFP23225.1 - 4.6e-11 42.2 0.1 1.4e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KFP23225.1 - 0.0021 17.1 0.0 0.0038 16.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain SH3_10 PF17902.1 KFP23225.1 - 0.0042 17.1 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KFP23225.1 - 0.014 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain zf-RING_14 PF17978.1 KFP23225.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YdjC PF04794.12 KFP23225.1 - 0.061 13.3 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 YdjC-like protein hSH3 PF14603.6 KFP23225.1 - 0.12 12.9 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain Thymidylat_synt PF00303.19 KFP23226.1 - 1.6e-104 348.8 0.0 1.8e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Clusterin PF01093.17 KFP23227.1 - 1.5e-170 567.9 6.7 1.7e-170 567.8 6.7 1.0 1 0 0 1 1 1 1 Clusterin Carbpep_Y_N PF05388.11 KFP23227.1 - 0.0003 21.3 0.4 0.07 13.7 0.3 2.8 3 0 0 3 3 3 1 Carboxypeptidase Y pro-peptide Sulfatase_C PF14707.6 KFP23227.1 - 0.17 12.6 9.4 2.3 9.0 0.0 3.4 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase Tox-ODYAM1 PF15642.6 KFP23227.1 - 0.7 8.8 4.9 1.1 8.1 4.9 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ALIX_LYPXL_bnd PF13949.6 KFP23227.1 - 1.3 8.2 12.3 4.3 6.6 6.4 3.6 2 2 2 4 4 4 0 ALIX V-shaped domain binding to HIV Collagen PF01391.18 KFP23229.1 - 4.8e-24 83.9 96.7 6.9e-10 38.5 30.7 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Lectin_C PF00059.21 KFP23229.1 - 2.6e-20 73.1 1.2 2.6e-20 73.1 1.2 2.3 2 0 0 2 2 2 1 Lectin C-type domain Filament PF00038.21 KFP23229.1 - 0.00029 20.6 29.0 0.00029 20.6 29.0 2.1 1 1 1 2 2 2 1 Intermediate filament protein Spc7 PF08317.11 KFP23229.1 - 0.0027 16.6 33.1 0.036 12.9 14.2 2.9 1 1 2 3 3 3 3 Spc7 kinetochore protein Fib_alpha PF08702.10 KFP23229.1 - 0.0056 16.9 37.3 0.01 16.0 7.0 3.9 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KFP23229.1 - 0.49 10.4 29.9 1.3 9.1 6.7 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 KFP23229.1 - 0.64 9.8 3.4 18 5.2 0.1 3.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Jnk-SapK_ap_N PF09744.9 KFP23229.1 - 0.89 9.8 26.0 0.19 12.0 4.0 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 KFP23229.1 - 1.5 6.2 34.4 5.6 4.3 19.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HalX PF08663.10 KFP23229.1 - 1.9 8.8 7.3 5.1 7.5 0.0 3.3 3 1 1 4 4 4 0 HalX domain NPV_P10 PF05531.12 KFP23229.1 - 4.7 7.7 26.8 0.42 11.1 4.6 5.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KFP23229.1 - 4.7 5.6 6.8 2.8 6.4 1.5 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF948 PF06103.11 KFP23229.1 - 5.2 7.4 29.1 1.3 9.3 1.9 5.0 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) KapB PF08810.10 KFP23229.1 - 5.5 7.2 6.9 4 7.7 2.2 2.7 2 2 0 2 2 2 0 Kinase associated protein B efThoc1 PF11957.8 KFP23230.1 - 6.1e-147 490.2 8.9 9.4e-147 489.6 8.9 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 KFP23230.1 - 4.3e-17 62.0 2.0 1.7e-16 60.1 0.7 2.5 2 0 0 2 2 2 1 Death domain JmjN PF02375.17 KFP23230.1 - 5.1 7.1 4.8 3.1 7.8 0.1 2.7 2 0 0 2 2 2 0 jmjN domain UCH PF00443.29 KFP23231.1 - 4.9e-50 170.4 0.6 5.7e-50 170.2 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFP23231.1 - 7.2e-13 48.8 4.1 1.7e-12 47.6 4.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFP23231.1 - 0.00059 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 KFP23231.1 - 0.00071 19.1 2.4 0.023 14.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase PFEMP PF03011.15 KFP23231.1 - 0.88 10.2 7.6 1.2 9.7 0.1 2.8 3 0 0 3 3 3 0 PFEMP DBL domain Pkinase PF00069.25 KFP23232.1 - 1.3e-62 211.6 0.0 1.3e-62 211.6 0.0 3.7 4 2 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFP23232.1 - 3.7e-30 105.1 0.0 3.7e-30 105.1 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Rho_Binding PF08912.11 KFP23232.1 - 5.8e-23 81.5 13.7 5.8e-23 81.5 13.7 13.3 3 2 8 12 12 12 1 Rho Binding PH PF00169.29 KFP23232.1 - 7.8e-06 26.4 5.1 7.6e-05 23.2 0.1 3.4 3 0 0 3 3 3 1 PH domain C1_1 PF00130.22 KFP23232.1 - 0.00039 20.2 5.9 0.00083 19.2 5.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 KFP23232.1 - 0.0012 18.9 0.3 0.029 14.3 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KFP23232.1 - 0.0029 18.3 1.3 0.01 16.5 1.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 KFP23232.1 - 0.009 16.1 14.0 0.009 16.1 14.0 10.9 6 3 3 9 9 9 2 Hr1 repeat DUF1192 PF06698.11 KFP23232.1 - 0.027 14.5 0.6 0.027 14.5 0.6 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) GREB1 PF15782.5 KFP23234.1 - 0 3198.5 17.5 0 1776.5 0.1 2.0 1 1 1 2 2 2 2 Gene regulated by oestrogen in breast cancer Rcd1 PF04078.13 KFP23234.1 - 0.0076 15.6 0.2 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like E7 PF00527.18 KFP23234.1 - 6.8 7.0 6.8 2.5 8.3 0.2 3.0 3 0 0 3 3 3 0 E7 protein, Early protein Acetyltransf_13 PF13880.6 KFP23235.1 - 1.4e-29 101.9 0.0 2.8e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KFP23235.1 - 2.9e-15 55.8 1.3 5.3e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Abhydrolase_1 PF00561.20 KFP23236.1 - 9.8e-10 38.5 0.0 9.1e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFP23236.1 - 3.4e-09 36.3 0.0 5.8e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFP23236.1 - 1.3e-06 29.2 0.0 1.8e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 KFP23237.1 - 2.5e-48 162.6 10.5 7.3e-15 55.3 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFP23237.1 - 4.2e-47 157.6 13.3 2.8e-13 49.8 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFP23237.1 - 7.3e-46 154.0 19.7 3.5e-11 43.4 0.1 7.7 2 1 7 9 9 9 8 Ankyrin repeats (many copies) SH3_15 PF18346.1 KFP23237.1 - 5.6e-44 148.3 6.3 1.5e-21 76.5 0.0 3.6 4 0 0 4 4 4 2 Mind bomb SH3 repeat domain Ank PF00023.30 KFP23237.1 - 8.9e-41 136.6 12.7 3.9e-08 33.4 0.9 9.2 8 1 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 KFP23237.1 - 2.3e-29 98.2 16.1 0.00058 20.1 0.3 10.5 12 0 0 12 12 10 6 Ankyrin repeat MIB_HERC2 PF06701.13 KFP23237.1 - 1.4e-28 98.9 4.8 1.4e-28 98.9 4.8 4.0 4 0 0 4 4 4 1 Mib_herc2 zf-C3HC4_3 PF13920.6 KFP23237.1 - 2.6e-27 94.4 59.6 1.8e-10 40.5 7.9 4.7 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 KFP23237.1 - 2.5e-11 43.2 8.4 2.5e-11 43.2 8.4 3.6 3 0 0 3 3 2 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 KFP23237.1 - 2.7e-08 33.5 9.8 2.7e-08 33.5 9.8 4.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP23237.1 - 0.00058 19.7 55.8 0.0095 15.8 8.3 5.1 4 1 1 5 5 4 3 Prokaryotic RING finger family 4 CtIP_N PF10482.9 KFP23239.1 - 1.5e-51 173.5 21.2 9.9e-51 170.8 21.2 2.5 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain SAE2 PF08573.10 KFP23239.1 - 3.6e-05 24.8 0.2 3.6e-05 24.8 0.2 5.7 4 2 1 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Cob_adeno_trans PF01923.18 KFP23239.1 - 0.061 13.5 3.1 0.16 12.1 3.1 1.8 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Herpes_UL6 PF01763.16 KFP23239.1 - 0.65 8.4 16.1 3.4 6.1 0.4 3.2 2 1 1 3 3 3 0 Herpesvirus UL6 like FapA PF03961.13 KFP23239.1 - 4 5.9 19.1 1.8 7.1 10.8 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3450 PF11932.8 KFP23239.1 - 4.3 6.6 16.0 0.67 9.2 8.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cyclin_N PF00134.23 KFP23240.1 - 5.8e-08 32.5 0.2 8.7e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPT PF03151.16 KFP23241.1 - 3.4e-05 23.3 2.5 4.4e-05 23.0 2.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TssN PF17555.2 KFP23241.1 - 0.024 14.0 1.7 0.042 13.2 1.7 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN EamA PF00892.20 KFP23241.1 - 0.1 12.8 17.6 0.35 11.0 8.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family RIO1 PF01163.22 KFP23242.1 - 1.1e-75 253.3 0.3 2.7e-75 252.1 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KFP23242.1 - 8.4e-05 22.1 0.2 0.0002 20.8 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFP23242.1 - 0.00047 19.6 0.2 0.0016 17.8 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFP23242.1 - 0.014 15.0 0.1 0.036 13.6 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KFP23242.1 - 0.039 12.7 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFP23242.1 - 0.048 13.6 0.2 0.99 9.3 0.2 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mic1 PF07035.12 KFP23243.1 - 7.2e-71 237.0 2.7 1e-70 236.5 1.1 1.9 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Patched PF02460.18 KFP23244.1 - 4.7e-84 283.0 25.2 3.6e-83 280.1 25.3 2.1 2 1 0 2 2 2 1 Patched family NPC1_N PF16414.5 KFP23244.1 - 7.2e-81 271.3 4.8 7.2e-81 271.3 4.8 1.8 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KFP23244.1 - 7.8e-57 191.4 7.4 7.8e-57 191.4 7.4 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KFP23244.1 - 0.00013 19.9 7.4 0.00013 19.9 7.4 2.1 2 1 0 2 2 2 1 AcrB/AcrD/AcrF family MMPL PF03176.15 KFP23244.1 - 0.00033 19.7 4.7 0.00033 19.7 4.7 2.3 2 0 0 2 2 2 1 MMPL family Ank_4 PF13637.6 KFP23245.1 - 1.2e-49 166.0 5.4 1.3e-08 35.2 0.0 6.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP23245.1 - 1.7e-49 166.4 0.9 9.3e-15 55.0 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KFP23245.1 - 2.5e-34 116.2 6.7 9.1e-06 25.9 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KFP23245.1 - 7.8e-32 108.9 6.1 4e-09 36.5 0.0 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP23245.1 - 8.8e-31 102.5 1.0 0.0027 18.1 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat NIT PF08376.10 KFP23245.1 - 0.02 15.4 0.3 0.14 12.6 0.1 2.2 2 1 0 2 2 2 0 Nitrate and nitrite sensing RVT_1 PF00078.27 KFP23246.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Laminin_EGF PF00053.24 KFP23247.1 - 5e-97 317.9 308.0 4.6e-10 39.5 11.3 16.7 15 2 2 17 17 17 15 Laminin EGF domain Laminin_G_2 PF02210.24 KFP23247.1 - 3.3e-76 253.9 0.0 6.8e-24 84.9 0.0 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_N PF00055.17 KFP23247.1 - 2.4e-68 230.2 0.0 2.4e-68 230.2 0.0 2.8 3 0 0 3 3 2 1 Laminin N-terminal (Domain VI) Laminin_G_1 PF00054.23 KFP23247.1 - 2.2e-61 205.8 0.0 8.8e-21 74.5 0.1 6.0 5 1 0 5 5 5 5 Laminin G domain Laminin_I PF06008.14 KFP23247.1 - 3.3e-55 187.6 28.6 3.3e-55 187.6 28.6 3.6 1 1 3 4 4 3 1 Laminin Domain I Laminin_II PF06009.12 KFP23247.1 - 7.8e-36 123.1 0.9 7.8e-36 123.1 0.9 5.7 2 1 3 6 6 6 1 Laminin Domain II Laminin_B PF00052.18 KFP23247.1 - 7.7e-31 106.8 0.0 2.1e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.6 KFP23247.1 - 3.9e-18 66.0 0.0 1.1e-07 32.1 0.0 3.7 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily Activator-TraM PF11657.8 KFP23247.1 - 0.0012 18.7 3.0 0.0033 17.3 3.0 1.8 1 0 0 1 1 1 1 Transcriptional activator TraM DUF16 PF01519.16 KFP23247.1 - 0.0066 16.9 25.8 0.14 12.7 1.3 4.8 4 1 0 4 4 4 2 Protein of unknown function DUF16 T3SchapCesA PF11439.8 KFP23247.1 - 3.7 7.7 6.4 5.3 7.2 0.1 3.4 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF3808 PF10300.9 KFP23248.1 - 9e-126 420.4 7.1 1.1e-125 420.2 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Cohesin_load PF10345.9 KFP23248.1 - 2.1e-07 29.8 1.3 2.1e-07 29.8 1.3 1.6 2 0 0 2 2 2 1 Cohesin loading factor TPR_2 PF07719.17 KFP23248.1 - 6.6e-06 25.8 1.3 0.39 10.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFP23248.1 - 0.00017 21.3 0.6 0.32 10.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFP23248.1 - 0.0022 18.3 0.2 1.7 9.0 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFP23248.1 - 0.0022 18.5 0.3 25 5.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFP23248.1 - 0.0036 16.7 0.4 15 4.8 0.0 3.5 3 1 0 3 3 3 1 MalT-like TPR region VEFS-Box PF09733.9 KFP23248.1 - 0.021 14.6 0.3 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 VEFS-Box of polycomb protein TPR_7 PF13176.6 KFP23248.1 - 0.038 14.0 0.1 0.43 10.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 KFP23249.1 - 6e-151 502.5 0.7 8.4e-151 502.0 0.7 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.30 KFP23249.1 - 1.8e-23 81.9 3.5 5.5e-08 32.9 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFP23249.1 - 8.4e-23 80.1 2.8 6.1e-09 36.0 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFP23249.1 - 5.9e-22 78.1 0.9 2.6e-13 50.3 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFP23249.1 - 7.1e-20 71.1 2.3 3.8e-05 24.1 0.0 5.4 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFP23249.1 - 7.2e-16 56.7 0.6 5.1e-05 23.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH_11 PF15413.6 KFP23249.1 - 0.0044 17.4 0.2 0.0044 17.4 0.2 3.7 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 KFP23249.1 - 0.01 16.3 0.7 0.01 16.3 0.7 3.2 3 0 0 3 3 3 0 PH domain UPF0029 PF01205.19 KFP23250.1 - 4.6e-35 120.1 0.0 7e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFP23250.1 - 3.8e-17 62.6 0.9 7.6e-17 61.7 0.8 1.6 2 0 0 2 2 2 1 RWD domain DUF677 PF05055.12 KFP23250.1 - 0.034 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) 7tm_1 PF00001.21 KFP23251.1 - 1.5e-58 198.3 10.9 1.6e-58 198.1 10.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KFP23251.1 - 0.0065 16.2 3.0 0.012 15.4 3.0 1.4 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KFP23251.1 - 0.0082 15.6 11.8 0.62 9.4 0.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.21 KFP23252.1 - 8.7e-62 208.8 11.3 1e-61 208.6 11.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KFP23252.1 - 1.6e-06 27.7 14.3 0.00058 19.3 9.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KFP23252.1 - 0.00055 19.8 7.2 0.001 18.9 7.2 1.4 1 0 0 1 1 1 1 Olfactory receptor DUF5381 PF17353.2 KFP23252.1 - 0.049 13.4 1.3 8.8 6.0 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5381) zf-C2H2_4 PF13894.6 KFP23254.1 - 2.5e-68 220.8 213.5 0.00037 21.1 0.8 31.2 31 0 0 31 31 31 26 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP23254.1 - 1.5e-49 163.8 218.9 0.0012 19.2 3.0 30.6 31 0 0 31 31 31 23 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFP23254.1 - 8.8e-34 114.9 181.2 9e-08 31.9 0.1 26.5 26 1 1 27 27 26 15 C2H2-type zinc finger zf-Di19 PF05605.12 KFP23254.1 - 6.8e-22 77.5 168.5 6.5e-05 23.1 3.4 19.3 15 3 4 20 20 20 12 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KFP23254.1 - 2.1e-19 69.0 188.1 6.7e-06 26.3 1.0 28.6 32 1 0 32 32 31 13 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFP23254.1 - 4.4e-10 39.6 182.0 0.013 15.7 0.6 25.9 29 0 0 29 29 28 12 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFP23254.1 - 2.7e-05 24.4 168.8 0.11 12.9 0.9 24.5 8 6 13 22 22 22 10 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFP23254.1 - 0.00014 22.1 14.1 0.0079 16.6 1.2 21.5 25 0 0 25 25 25 8 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFP23254.1 - 0.01 16.1 1.6 0.01 16.1 1.6 13.9 9 4 4 14 14 14 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KFP23254.1 - 0.063 13.2 0.1 0.063 13.2 0.1 16.9 18 1 1 19 19 18 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KFP23254.1 - 0.11 13.0 0.2 0.11 13.0 0.2 11.2 13 0 0 13 13 10 0 Autophagy receptor zinc finger-C2H2 domain TAF4 PF05236.14 KFP23256.1 - 8.2e-52 176.7 8.6 1.2e-51 176.1 8.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 KFP23256.1 - 1.1e-39 134.5 4.3 3.4e-39 132.8 4.3 2.0 1 0 0 1 1 1 1 NHR1 homology to TAF RVT_1 PF00078.27 KFP23257.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB_2 PF02214.22 KFP23259.1 - 2.5e-17 63.0 0.0 4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MIP PF00230.20 KFP23261.1 - 1.8e-72 243.8 14.3 2.2e-72 243.4 14.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sulfotransfer_2 PF03567.14 KFP23262.1 - 6.6e-61 206.4 2.0 9e-61 206.0 2.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.17 KFP23264.1 - 1.4e-90 297.9 1.8 5.2e-23 81.3 0.1 5.8 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.17 KFP23264.1 - 1.5e-53 181.0 0.4 3e-53 180.0 0.4 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.11 KFP23264.1 - 4.7e-30 103.6 0.1 4.8e-29 100.4 0.1 2.4 2 0 0 2 2 2 1 Cadherin prodomain like Cadherin_3 PF16184.5 KFP23264.1 - 1.1e-06 28.6 5.4 0.035 14.1 0.1 4.7 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KFP23264.1 - 7.7e-05 22.4 0.0 3.8 7.4 0.0 3.4 3 0 0 3 3 3 2 Cadherin-like He_PIG PF05345.12 KFP23264.1 - 0.00032 20.8 9.6 0.89 9.8 0.4 5.9 5 1 0 5 5 5 2 Putative Ig domain Cadherin_4 PF17803.1 KFP23264.1 - 0.0055 17.3 20.6 0.074 13.7 0.1 4.9 5 0 0 5 5 4 2 Bacterial cadherin-like domain EphA2_TM PF14575.6 KFP23264.1 - 0.015 16.1 0.0 0.035 15.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 KFP23264.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Prok-E2_A PF14457.6 KFP23264.1 - 0.14 11.8 0.3 4.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family A DUF4381 PF14316.6 KFP23264.1 - 0.19 12.0 0.1 0.34 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5385 PF17359.2 KFP23264.1 - 1.6 8.3 4.4 0.22 11.1 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Big_9 PF17963.1 KFP23264.1 - 8.1 7.3 24.5 0.14 12.9 0.5 5.0 4 1 1 5 5 5 0 Bacterial Ig domain KH_1 PF00013.29 KFP23268.1 - 1.1e-21 76.4 0.8 3.6e-14 52.3 0.1 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.6 KFP23268.1 - 4.4e-11 42.4 11.4 6.5e-11 41.9 11.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFP23268.1 - 8.3e-07 28.8 10.8 1.4e-06 28.1 10.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFP23268.1 - 5.8e-05 22.9 13.1 9.5e-05 22.2 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFP23268.1 - 0.019 15.0 5.5 0.019 15.0 5.5 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFP23268.1 - 0.05 13.6 11.1 0.092 12.7 11.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2HC5 PF06221.13 KFP23268.1 - 0.073 13.1 5.8 0.18 11.9 5.8 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type KH_2 PF07650.17 KFP23268.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 KH domain zf-RING_4 PF14570.6 KFP23268.1 - 0.59 10.0 8.9 1.2 9.0 8.9 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Malic_M PF03949.15 KFP23269.1 - 2.5e-97 325.2 0.2 3.3e-97 324.8 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFP23269.1 - 1.2e-79 266.3 0.0 2.2e-79 265.5 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pol_alpha_B_N PF08418.10 KFP23269.1 - 0.047 13.7 0.1 0.082 12.9 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SKA1 PF07160.12 KFP23270.1 - 6.7e-85 284.8 5.9 7.5e-85 284.6 5.9 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 CREPT PF16566.5 KFP23270.1 - 0.0035 17.5 0.7 0.0073 16.5 0.7 1.5 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF3161 PF11362.8 KFP23270.1 - 0.0048 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) SlyX PF04102.12 KFP23270.1 - 0.044 14.4 3.1 0.98 10.1 2.8 2.5 2 0 0 2 2 2 0 SlyX DUF2894 PF11445.8 KFP23270.1 - 0.094 13.2 1.8 0.16 12.4 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF4462 PF14692.6 KFP23271.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Myosin_head PF00063.21 KFP23272.1 - 1.1e-281 936.1 10.1 1.3e-281 935.8 10.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KFP23272.1 - 2e-15 55.0 27.6 3.8e-05 23.1 1.3 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KFP23272.1 - 0.00085 19.1 1.5 0.0014 18.4 0.4 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFP23272.1 - 0.0016 18.7 0.3 0.02 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFP23272.1 - 0.015 15.7 0.2 0.072 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KFP23272.1 - 0.09 11.8 0.1 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF218 PF02698.17 KFP23272.1 - 0.39 10.7 3.5 4.7 7.3 1.3 2.4 2 0 0 2 2 2 0 DUF218 domain Csm1_N PF18504.1 KFP23275.1 - 0.0032 17.8 16.8 0.067 13.5 4.1 2.5 2 0 0 2 2 2 2 Csm1 N-terminal domain FapA PF03961.13 KFP23275.1 - 0.0054 15.4 13.1 0.0059 15.3 13.1 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Taxilin PF09728.9 KFP23275.1 - 0.0098 15.1 8.9 0.0098 15.1 8.9 2.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF2508 PF10704.9 KFP23275.1 - 0.014 15.5 2.9 0.014 15.5 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) bZIP_1 PF00170.21 KFP23275.1 - 0.023 14.8 7.4 0.023 14.8 7.4 2.7 3 0 0 3 3 2 0 bZIP transcription factor IZUMO PF15005.6 KFP23275.1 - 0.045 14.3 13.6 0.033 14.7 12.3 1.4 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF4407 PF14362.6 KFP23275.1 - 0.06 12.7 11.1 0.077 12.3 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2492 PF10678.9 KFP23275.1 - 0.082 13.2 1.8 0.15 12.3 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) LMBR1 PF04791.16 KFP23275.1 - 0.12 11.3 10.5 0.13 11.1 10.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ApoO PF09769.9 KFP23275.1 - 0.14 12.1 4.1 0.52 10.3 0.4 2.1 2 0 0 2 2 2 0 Apolipoprotein O Peptidase_C9 PF01707.16 KFP23275.1 - 0.15 11.6 0.3 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Peptidase family C9 OmpH PF03938.14 KFP23275.1 - 0.38 11.1 30.5 1.4 9.3 21.8 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KFP23275.1 - 0.61 10.6 29.5 0.68 10.5 16.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFP23275.1 - 0.68 10.2 23.6 1.5 9.1 9.7 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KFP23275.1 - 0.74 9.8 25.8 1.1 9.3 25.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4795 PF16043.5 KFP23275.1 - 0.95 9.0 17.3 1.2 8.6 17.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Ax_dynein_light PF10211.9 KFP23275.1 - 1.1 9.2 22.5 2.9 7.8 12.0 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Clr5 PF14420.6 KFP23275.1 - 1.1 9.5 7.2 2.1 8.6 3.3 2.6 2 1 0 2 2 1 0 Clr5 domain DUF2383 PF09537.10 KFP23275.1 - 1.3 9.4 10.5 0.5 10.7 1.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) GAS PF13851.6 KFP23275.1 - 1.3 8.3 28.7 0.22 10.8 14.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 KFP23275.1 - 1.3 8.8 17.3 3.7 7.3 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KFP23275.1 - 1.6 6.5 14.3 1.9 6.3 14.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 KFP23275.1 - 1.7 9.0 21.5 9 6.7 21.5 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlxA PF14282.6 KFP23275.1 - 2.7 8.0 22.2 7.3 6.7 7.4 2.8 1 1 1 2 2 2 0 FlxA-like protein zf-C4H2 PF10146.9 KFP23275.1 - 3.2 8.0 12.8 4.3 7.6 12.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein NPV_P10 PF05531.12 KFP23275.1 - 3.3 8.3 9.6 3.5 8.2 2.2 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM184 PF15665.5 KFP23275.1 - 3.3 7.4 25.6 0.67 9.7 16.9 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B RasGAP_C PF03836.15 KFP23275.1 - 3.7 7.7 16.0 6.7 6.8 7.1 2.4 1 1 1 2 2 2 0 RasGAP C-terminus TolA_bind_tri PF16331.5 KFP23275.1 - 3.8 7.7 19.4 2.2 8.4 5.8 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation HU-CCDC81_bac_2 PF18175.1 KFP23275.1 - 4.1 7.4 9.0 4.9 7.1 2.2 2.4 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 ALMT PF11744.8 KFP23275.1 - 4.9 5.9 9.6 5.5 5.7 9.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 KFP23275.1 - 5.5 6.5 12.3 6.6 6.2 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit betaPIX_CC PF16523.5 KFP23275.1 - 5.5 6.9 19.1 0.66 9.8 5.0 2.6 3 0 0 3 3 2 0 betaPIX coiled coil TEX13 PF15186.6 KFP23275.1 - 6.7 6.4 17.8 1.8 8.2 6.8 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family SlyX PF04102.12 KFP23275.1 - 7.4 7.3 18.6 11 6.7 0.9 3.4 1 1 2 3 3 3 0 SlyX Sulfatase_C PF14707.6 KFP23275.1 - 8.5 7.1 7.4 22 5.8 1.3 2.3 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Seryl_tRNA_N PF02403.22 KFP23275.1 - 8.7 6.6 18.6 51 4.2 16.7 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPD52 PF04201.15 KFP23275.1 - 9.3 5.8 13.6 2.5 7.7 10.2 1.7 1 1 1 2 2 2 0 Tumour protein D52 family Thiolase_N PF00108.23 KFP23276.1 - 1.1e-90 303.6 0.2 1.9e-90 302.7 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFP23276.1 - 2.9e-53 178.7 0.3 6.2e-53 177.7 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFP23276.1 - 1.9e-05 24.4 0.7 0.0019 17.8 0.3 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KFP23276.1 - 0.057 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_L22 PF00237.19 KFP23277.1 - 3.2e-49 165.4 0.1 4.8e-49 164.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Dymeclin PF09742.9 KFP23279.1 - 1.1e-178 595.6 13.9 1.2e-178 595.4 13.9 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KFP23279.1 - 4.4e-10 38.4 20.7 6.7e-07 27.9 7.2 3.7 3 1 1 4 4 4 3 High-temperature-induced dauer-formation protein MH2 PF03166.14 KFP23282.1 - 1.5e-50 172.0 0.4 1.8e-50 171.8 0.4 1.0 1 0 0 1 1 1 1 MH2 domain BTB PF00651.31 KFP23284.1 - 2.6e-33 114.5 1.3 1.8e-32 111.8 0.5 2.2 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFP23284.1 - 2.3e-11 43.6 24.4 2.7e-06 27.5 3.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFP23284.1 - 3.5e-08 33.6 7.7 0.0029 18.3 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFP23284.1 - 6e-08 32.7 10.2 6.9e-05 23.1 1.4 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type BSP_II PF05432.11 KFP23284.1 - 0.0073 16.0 10.3 0.011 15.4 10.3 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) zf-met PF12874.7 KFP23284.1 - 0.0086 16.4 6.4 0.073 13.5 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 KFP23284.1 - 0.017 15.4 0.8 1 9.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon DUF3268 PF11672.8 KFP23284.1 - 0.045 14.1 1.2 0.35 11.2 0.7 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_6 PF13912.6 KFP23284.1 - 0.058 13.4 0.1 0.058 13.4 0.1 3.3 3 0 0 3 3 2 0 C2H2-type zinc finger RXT2_N PF08595.11 KFP23284.1 - 0.069 13.2 4.3 0.13 12.3 4.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 KFP23284.1 - 0.073 11.4 7.2 0.11 10.8 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_9 PF16293.5 KFP23284.1 - 0.093 12.6 0.5 16 5.4 0.1 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KFP23284.1 - 0.16 11.8 1.7 0.43 10.4 0.1 2.3 1 1 1 2 2 2 0 GAGA factor DUF4611 PF15387.6 KFP23284.1 - 0.23 11.7 9.7 0.5 10.6 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFB6 PF17110.5 KFP23284.1 - 0.43 10.3 5.5 0.73 9.6 5.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF719 PF05334.13 KFP23284.1 - 0.43 10.8 1.7 0.72 10.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) SDA1 PF05285.12 KFP23284.1 - 0.51 9.7 13.8 0.8 9.1 13.8 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 KFP23284.1 - 0.68 9.6 9.9 1.5 8.5 9.9 1.5 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 KFP23284.1 - 0.74 9.2 13.3 1.1 8.6 13.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-C2H2_jaz PF12171.8 KFP23284.1 - 0.75 10.2 11.6 25 5.3 0.3 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding PDDEXK_6 PF04720.12 KFP23284.1 - 0.76 9.7 3.3 1.5 8.7 3.3 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function TRAP_alpha PF03896.16 KFP23284.1 - 0.89 8.7 7.4 1.4 8.0 7.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Endonuclease_7 PF02945.15 KFP23284.1 - 1.6 8.7 7.5 87 3.1 7.5 2.6 1 1 0 1 1 1 0 Recombination endonuclease VII zf-C2H2_2 PF12756.7 KFP23284.1 - 1.9 8.9 6.3 5.7 7.3 0.9 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) BUD22 PF09073.10 KFP23284.1 - 2.6 7.3 11.3 3.8 6.8 11.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 KFP23284.1 - 2.7 6.8 7.7 3.8 6.4 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.9 KFP23284.1 - 3.2 6.8 20.8 4.7 6.3 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 KFP23284.1 - 3.5 7.8 17.6 9.4 6.4 17.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 KFP23284.1 - 4.4 5.3 6.8 5.7 4.9 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PI3K_1B_p101 PF10486.9 KFP23284.1 - 4.6 4.9 6.9 6.3 4.4 6.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Radial_spoke PF04712.12 KFP23284.1 - 4.7 6.0 11.2 7.2 5.4 11.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 KFP23284.1 - 4.7 5.3 18.2 6.7 4.8 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.12 KFP23284.1 - 5.2 4.9 9.0 7.2 4.4 9.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RRN3 PF05327.11 KFP23284.1 - 5.9 5.3 11.8 8.4 4.8 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 KFP23284.1 - 7.3 6.9 15.6 14 5.9 15.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Yos1 PF08571.10 KFP23286.1 - 8.3e-16 58.0 0.0 8.7e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Yos1-like DUF4462 PF14692.6 KFP23287.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Hydrolase_like PF13242.6 KFP23288.1 - 6.9e-20 70.9 0.0 1.4e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFP23288.1 - 2.2e-14 53.4 0.0 3.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFP23288.1 - 3.5e-07 30.5 0.0 6.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFP23288.1 - 0.00095 19.5 0.3 0.0062 16.9 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tautomerase PF01361.21 KFP23288.1 - 0.09 12.7 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme DUF4032 PF13224.6 KFP23288.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) PINIT PF14324.6 KFP23291.1 - 4.1e-35 121.3 0.0 9e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFP23291.1 - 5.5e-22 77.3 5.2 1.1e-21 76.3 5.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFP23291.1 - 0.00017 21.3 1.6 0.00046 19.9 1.6 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KFP23291.1 - 0.019 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 SAP domain PHD PF00628.29 KFP23291.1 - 0.2 11.6 2.2 0.42 10.5 2.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KFP23295.1 - 1.3e-14 54.2 6.2 1.3e-14 54.2 6.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFP23295.1 - 2.9e-11 43.0 6.9 2.9e-11 43.0 6.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFP23295.1 - 5.5e-09 35.6 1.9 5.5e-09 35.6 1.9 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFP23295.1 - 5e-08 32.7 3.8 9.6e-08 31.8 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFP23295.1 - 1.8e-07 30.9 4.8 1.8e-07 30.9 4.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFP23295.1 - 2.4e-07 30.9 6.3 2.4e-07 30.9 6.3 1.9 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFP23295.1 - 8.1e-07 28.9 3.2 8.1e-07 28.9 3.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFP23295.1 - 1.5e-05 24.9 2.2 3.8e-05 23.6 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFP23295.1 - 5e-05 23.1 4.1 5e-05 23.1 4.1 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFP23295.1 - 0.003 17.6 4.3 0.0074 16.3 4.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFP23295.1 - 0.031 13.9 5.1 0.069 12.8 5.1 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type OrfB_Zn_ribbon PF07282.11 KFP23295.1 - 0.059 13.3 0.7 1.4 8.9 0.1 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-Nse PF11789.8 KFP23295.1 - 0.066 13.0 1.3 0.17 11.7 1.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KFP23295.1 - 0.068 13.0 3.8 0.12 12.2 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFP23295.1 - 0.096 12.8 6.3 0.27 11.4 6.3 1.8 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KFP23295.1 - 0.16 11.9 4.0 2.2 8.3 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KFP23295.1 - 0.23 11.6 5.0 0.94 9.7 5.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KFP23295.1 - 0.54 10.6 3.7 1 9.7 3.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-P11 PF03854.14 KFP23295.1 - 0.75 9.5 3.6 0.48 10.1 0.8 2.0 2 0 0 2 2 2 0 P-11 zinc finger RNF111_N PF15303.6 KFP23296.1 - 9e-45 153.6 27.9 9e-45 153.6 27.9 1.9 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus SpoOE-like PF09388.10 KFP23297.1 - 0.039 13.9 0.2 0.039 13.9 0.2 2.8 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein DMPK_coil PF08826.10 KFP23297.1 - 0.055 13.6 1.4 0.055 13.6 1.4 3.9 3 1 1 4 4 4 0 DMPK coiled coil domain like Atg14 PF10186.9 KFP23297.1 - 0.13 11.3 12.0 0.37 9.8 12.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KFP23297.1 - 0.14 12.8 11.9 0.089 13.4 4.0 3.0 2 1 1 3 3 3 0 Initiation control protein YabA GAS PF13851.6 KFP23297.1 - 0.15 11.4 17.6 0.074 12.4 7.4 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Hrs_helical PF12210.8 KFP23297.1 - 0.16 12.5 4.4 0.18 12.4 0.3 2.7 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TPD52 PF04201.15 KFP23297.1 - 0.46 10.1 8.8 0.89 9.1 2.0 2.3 2 0 0 2 2 2 0 Tumour protein D52 family THP2 PF09432.10 KFP23297.1 - 0.87 9.7 10.0 0.11 12.5 1.1 2.9 2 1 0 3 3 3 0 Tho complex subunit THP2 ATG16 PF08614.11 KFP23297.1 - 1.5 9.0 16.2 9.8 6.4 15.4 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 KFP23297.1 - 1.7 8.7 12.9 0.59 10.1 9.9 1.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 KFP23297.1 - 3.3 8.2 20.7 6.8 7.2 10.9 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region CRR7 PF12095.8 KFP23297.1 - 5.4 7.5 7.0 2.6 8.6 0.7 2.9 3 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1664 PF07889.12 KFP23297.1 - 5.6 7.0 7.2 22 5.1 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cauli_AT PF03233.13 KFP23297.1 - 7.8 6.4 8.3 6.1 6.7 1.8 2.4 1 1 1 2 2 2 0 Aphid transmission protein ATP-synt_ab PF00006.25 KFP23298.1 - 2e-74 249.8 0.0 3.1e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFP23298.1 - 4.4e-27 94.9 2.0 1.4e-13 51.3 0.1 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFP23298.1 - 1.2e-17 64.2 1.8 2.9e-17 62.9 1.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 KFP23298.1 - 0.001 19.3 0.9 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4142) FCH PF00611.23 KFP23299.1 - 1.7e-13 50.7 1.1 1.1e-12 48.1 0.0 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HEPN_DZIP3 PF18738.1 KFP23299.1 - 0.048 13.4 2.3 0.074 12.8 0.3 2.2 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Spc7 PF08317.11 KFP23299.1 - 0.41 9.5 17.4 0.19 10.5 9.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KFP23299.1 - 0.86 9.7 5.1 0.33 11.1 1.1 2.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 KFP23299.1 - 2.5 8.6 9.0 0.82 10.1 5.0 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Alpha-amylase_N PF02903.14 KFP23300.1 - 0.01 16.0 0.2 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain UCH PF00443.29 KFP23300.1 - 0.025 14.1 0.1 0.058 12.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase EutA PF06277.11 KFP23300.1 - 0.27 10.0 1.5 0.34 9.7 0.2 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA V-set PF07686.17 KFP23301.1 - 5.3e-12 45.9 0.1 1e-10 41.7 0.0 2.3 2 1 1 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.16 KFP23301.1 - 2.9e-10 40.1 0.2 1.1e-05 25.3 0.1 3.5 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KFP23301.1 - 5.3e-10 39.8 3.1 1.2e-05 25.8 0.3 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KFP23301.1 - 1.5e-08 34.8 1.8 0.0001 22.6 0.2 2.7 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KFP23301.1 - 6.9e-05 22.9 4.1 1.4 9.1 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KFP23301.1 - 0.0031 17.5 0.2 0.01 15.9 0.1 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain AT_hook PF02178.19 KFP23303.1 - 4.3 7.5 39.9 0.1 12.5 1.5 5.2 4 0 0 4 4 4 0 AT hook motif RVT_1 PF00078.27 KFP23306.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KFP23309.1 - 4.7e-44 148.9 0.0 5.3e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain PTEN_C2 PF10409.9 KFP23309.1 - 0.0078 16.0 0.1 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein CEP76-C2 PF15627.6 KFP23309.1 - 0.023 14.2 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain Ras PF00071.22 KFP23312.1 - 5.2e-43 146.4 0.0 6.1e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFP23312.1 - 4.9e-11 42.9 0.0 7.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFP23312.1 - 3.5e-05 23.3 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFP23312.1 - 0.0017 17.9 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFP23312.1 - 0.0067 16.2 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NADH_Oxid_Nqo15 PF11497.8 KFP23312.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 PI3Ka PF00613.20 KFP23315.1 - 3.9e-58 195.9 1.0 7.8e-58 194.9 1.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFP23315.1 - 1.1e-53 182.7 0.0 1.5e-37 129.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KFP23315.1 - 2.2e-49 167.0 0.0 4.2e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KFP23315.1 - 0.005 16.2 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) HEAT_2 PF13646.6 KFP23315.1 - 0.0065 16.8 0.1 0.016 15.6 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats Yae1_N PF09811.9 KFP23319.1 - 2.2e-06 27.3 19.5 0.15 11.8 19.1 2.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 KFP23327.1 - 0.00028 20.7 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ins145_P3_rec PF08709.11 KFP23327.1 - 0.0051 16.0 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Egretta_garzetta-ASM68718v1/GCA_000687185.1_ASM68718v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Egretta_garzetta-ASM68718v1/GCA_000687185.1_ASM68718v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Egretta_garzetta-ASM68718v1/GCA_000687185.1_ASM68718v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Chordates/Egretta_garzetta-ASM68718v1/GCA_000687185.1_ASM68718v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 18:07:06 2019 # [ok]