# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- OMP_b-brl_2 PF13568.6 KEG05098.1 - 0.025 14.6 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Orf78 PF06024.12 KEG05098.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) MAP7 PF05672.11 KEG05099.1 - 0.013 15.2 65.8 0.015 15.0 65.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Fibrinogen_BP PF08017.11 KEG05099.1 - 0.017 13.6 35.9 0.018 13.5 35.9 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein FAM25 PF15825.5 KEG05099.1 - 1.4 9.3 21.6 2.8 8.4 7.5 3.1 1 1 2 3 3 3 0 FAM25 family Peptidase_M8 PF01457.16 KEG05100.1 - 5.9e-11 41.7 0.0 6.4e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF4398 PF14346.6 KEG05101.1 - 0.69 10.6 9.0 0.22 12.1 5.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DUF4094 PF13334.6 KEG05104.1 - 0.013 15.9 0.5 0.027 14.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) EphA2_TM PF14575.6 KEG05107.1 - 0.066 14.1 0.0 0.098 13.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 KEG05107.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 ATP_synth_reg PF14960.6 KEG05108.1 - 0.031 13.8 0.2 0.057 12.9 0.2 1.4 1 0 0 1 1 1 0 ATP synthase regulation Guanylate_cyc PF00211.20 KEG05112.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Orthoreo_P10 PF07204.11 KEG05112.1 - 0.046 13.7 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Bac_luciferase PF00296.20 KEG05113.1 - 0.049 13.1 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Peripla_BP_6 PF13458.6 KEG05114.1 - 0.0072 16.0 0.1 0.008 15.9 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein RVT_1 PF00078.27 KEG05115.1 - 6.1e-15 55.3 0.0 6.7e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2976 PF11190.8 KEG05115.1 - 0.034 14.0 0.0 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) TNRC6-PABC_bdg PF16608.5 KEG05116.1 - 0.068 12.9 0.1 0.072 12.8 0.1 1.1 1 0 0 1 1 1 0 TNRC6-PABC binding domain BRCA2 PF00634.18 KEG05121.1 - 0.098 12.4 0.2 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 BRCA2 repeat Phage_TAC_7 PF10109.9 KEG05121.1 - 0.15 12.2 5.0 2.5 8.3 0.4 2.8 1 1 2 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 Selenoprotein_S PF06936.11 KEG05124.1 - 1.6 8.5 5.0 2 8.2 5.0 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Arabino_trans_N PF17689.1 KEG05127.1 - 0.02 15.1 0.5 0.031 14.5 0.3 1.5 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain DUF4164 PF13747.6 KEG05128.1 - 0.00023 21.4 27.7 0.28 11.5 6.0 3.9 1 1 2 3 3 3 3 Domain of unknown function (DUF4164) Rootletin PF15035.6 KEG05128.1 - 0.00044 20.3 33.8 0.0026 17.8 11.8 2.2 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion DUF3829 PF12889.7 KEG05128.1 - 0.0032 17.0 8.4 0.0041 16.7 8.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) LsmAD PF06741.13 KEG05128.1 - 0.0034 17.9 30.1 0.98 10.0 9.8 3.4 1 1 2 3 3 3 3 LsmAD domain MCPsignal PF00015.21 KEG05128.1 - 0.0072 16.2 4.2 0.0089 15.9 4.2 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 KEG05128.1 - 0.015 15.5 8.0 0.79 10.0 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cep57_CLD_2 PF14197.6 KEG05128.1 - 0.017 15.2 16.1 0.017 15.2 16.1 4.4 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 KEG05128.1 - 0.019 15.5 50.9 0.56 10.7 30.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 KEG05128.1 - 0.019 15.6 10.3 0.019 15.6 10.3 2.8 1 1 1 2 2 1 0 SlyX Fe_dep_repress PF01325.19 KEG05128.1 - 0.02 15.1 10.0 8 6.8 0.4 4.2 1 1 3 4 4 4 0 Iron dependent repressor, N-terminal DNA binding domain UPF0242 PF06785.11 KEG05128.1 - 0.032 14.4 34.9 1.2 9.2 15.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CHDCT2 PF08074.11 KEG05128.1 - 0.04 14.1 4.6 0.054 13.7 4.6 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain TMF_TATA_bd PF12325.8 KEG05128.1 - 0.061 13.6 35.6 0.017 15.4 24.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KEG05128.1 - 0.069 13.6 30.4 0.5 10.8 10.9 2.0 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KEG05128.1 - 0.092 11.6 32.8 0.11 11.3 32.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KEG05128.1 - 0.12 13.0 30.3 0.51 11.0 9.8 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 KEG05128.1 - 0.17 11.9 40.6 1.3 9.0 16.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 KEG05128.1 - 0.2 10.7 21.7 0.23 10.5 21.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SHE3 PF17078.5 KEG05128.1 - 0.2 11.4 25.8 0.11 12.2 21.9 1.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 EspB PF05802.11 KEG05128.1 - 0.21 11.6 10.4 0.22 11.5 4.4 2.2 1 1 1 2 2 2 0 Enterobacterial EspB protein PilJ PF13675.6 KEG05128.1 - 0.22 11.5 3.8 0.4 10.7 3.8 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Csm1_N PF18504.1 KEG05128.1 - 0.24 11.8 36.0 3.7 8.0 2.9 4.0 1 1 3 4 4 4 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 KEG05128.1 - 0.25 11.1 29.2 1 9.2 17.9 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF2383 PF09537.10 KEG05128.1 - 0.26 11.6 19.1 0.34 11.3 2.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2383) FlgN PF05130.12 KEG05128.1 - 0.27 11.7 25.5 3.6 8.1 25.2 2.5 1 1 0 1 1 1 0 FlgN protein Mod_r PF07200.13 KEG05128.1 - 0.3 11.2 31.1 0.41 10.8 14.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PRKG1_interact PF15898.5 KEG05128.1 - 0.31 12.0 31.4 0.31 11.9 17.8 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF641 PF04859.12 KEG05128.1 - 0.39 11.1 27.4 0.57 10.5 8.2 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ERM PF00769.19 KEG05128.1 - 0.42 10.4 41.1 0.78 9.5 41.1 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SKA2 PF16740.5 KEG05128.1 - 0.51 10.1 20.6 1.8 8.4 9.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Jnk-SapK_ap_N PF09744.9 KEG05128.1 - 0.51 10.5 38.3 0.26 11.5 18.7 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 GAS PF13851.6 KEG05128.1 - 0.54 9.6 38.4 3.9 6.8 15.0 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KEG05128.1 - 0.57 9.6 33.2 0.78 9.2 18.6 1.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 KEG05128.1 - 0.64 10.7 27.3 0.48 11.1 9.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA IFT57 PF10498.9 KEG05128.1 - 0.65 8.9 20.0 1.3 7.9 20.0 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Muted PF14942.6 KEG05128.1 - 0.66 10.3 28.3 1.4 9.3 10.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 KEG05128.1 - 0.72 9.4 15.8 0.84 9.1 15.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Aida_N PF08910.10 KEG05128.1 - 0.74 10.2 7.8 0.41 11.0 3.6 2.2 1 1 1 2 2 2 0 Aida N-terminus DUF773 PF05600.12 KEG05128.1 - 0.83 8.3 21.4 0.18 10.5 7.0 2.1 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 Transglut_i_TM PF14400.6 KEG05128.1 - 0.83 9.7 9.6 5.2 7.1 2.9 2.4 1 1 1 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices Nnf1 PF03980.14 KEG05128.1 - 1.1 9.7 38.2 0.19 12.1 6.1 4.4 1 1 4 5 5 5 0 Nnf1 DUF1664 PF07889.12 KEG05128.1 - 1.4 8.9 6.7 2 8.5 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Acyl-CoA_dh_C PF12806.7 KEG05128.1 - 1.5 9.0 8.5 0.74 10.0 2.0 2.3 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DUF812 PF05667.11 KEG05128.1 - 1.8 7.3 31.1 1.1 8.1 11.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) 4HB_MCP_1 PF12729.7 KEG05128.1 - 1.9 8.0 23.3 1.5 8.3 13.7 2.1 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction FAM184 PF15665.5 KEG05128.1 - 2 8.1 30.6 4.5 7.0 24.2 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B FapA PF03961.13 KEG05128.1 - 2.2 6.8 20.9 5.7 5.4 20.9 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A HAP1_N PF04849.13 KEG05128.1 - 2.3 7.4 31.7 0.58 9.3 16.6 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region XRCC4 PF06632.12 KEG05128.1 - 2.4 6.9 24.7 3.2 6.5 24.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4200 PF13863.6 KEG05128.1 - 3.2 8.2 35.8 3 8.3 31.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MIP-T3_C PF17749.1 KEG05128.1 - 3.6 7.5 20.7 0.84 9.6 5.4 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region bZIP_1 PF00170.21 KEG05128.1 - 3.9 7.7 40.3 2.7 8.2 11.5 4.1 1 1 3 4 4 4 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 KEG05128.1 - 4 7.7 28.1 1.6 9.0 15.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain EspB_PE PF18625.1 KEG05128.1 - 4 8.0 21.1 0.58 10.6 0.9 3.8 2 2 3 5 5 5 0 ESX-1 secreted protein B PE domain KxDL PF10241.9 KEG05128.1 - 4.3 7.7 13.7 4.8 7.5 5.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein Flu_NS2 PF00601.19 KEG05128.1 - 4.5 7.6 15.7 3.5 8.0 1.3 3.3 1 1 2 3 3 3 0 Influenza non-structural protein (NS2) DUF2203 PF09969.9 KEG05128.1 - 4.8 7.9 20.1 2.4 8.9 7.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ATG11 PF10377.9 KEG05128.1 - 5.1 7.2 8.1 10 6.2 1.8 2.3 2 0 0 2 2 2 0 Autophagy-related protein 11 OmpH PF03938.14 KEG05128.1 - 5.6 7.3 35.4 1.5e+02 2.6 33.7 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5621 PF18532.1 KEG05128.1 - 5.6 6.9 16.5 0.79 9.6 2.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5621) Mto2_bdg PF12808.7 KEG05128.1 - 7.1 7.0 42.1 1.4 9.2 5.0 5.8 1 1 3 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMPIT PF07851.13 KEG05128.1 - 8.1 5.6 17.6 17 4.5 17.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein Peptidase_S46 PF10459.9 KEG05128.1 - 9.1 4.8 15.4 9.1 4.8 15.4 1.0 1 0 0 1 1 1 0 Peptidase S46 Golgin_A5 PF09787.9 KEG05128.1 - 9.3 5.6 27.9 11 5.4 27.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 GrpE PF01025.19 KEG05128.1 - 9.5 5.9 34.9 4.5 6.9 13.3 2.1 1 1 1 2 2 2 0 GrpE CENP-H PF05837.12 KEG05128.1 - 9.5 6.7 28.2 4.1 7.8 13.5 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SPACA9 PF15120.6 KEG05128.1 - 9.6 6.0 10.1 9.9 5.9 1.1 2.7 1 1 1 2 2 2 0 Sperm acrosome-associated protein 9 DUF4201 PF13870.6 KEG05128.1 - 10 5.8 30.7 40 3.9 10.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Mucin PF01456.17 KEG05130.1 - 2e-07 31.1 5.8 2.3e-07 30.9 5.8 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF5324 PF17258.2 KEG05132.1 - 0.0057 16.4 3.3 0.0075 16.0 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5324) DUF4147 PF13660.6 KEG05132.1 - 0.013 15.1 0.8 0.017 14.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) DUF4282 PF14110.6 KEG05134.1 - 0.27 12.0 3.6 0.38 11.5 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF5566 PF17721.1 KEG05135.1 - 0.0046 17.3 0.5 0.0052 17.1 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5566) TPR_2 PF07719.17 KEG05135.1 - 0.089 12.9 1.9 0.089 12.9 1.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Alanine_zipper PF11839.8 KEG05135.1 - 0.16 12.3 43.4 0.19 12.1 11.6 3.6 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein SNARE PF05739.19 KEG05135.1 - 0.22 11.6 1.2 1.2 9.2 1.2 2.2 1 1 0 1 1 1 0 SNARE domain LEA_4 PF02987.16 KEG05135.1 - 0.26 11.4 15.9 0.25 11.4 1.4 3.4 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF4398 PF14346.6 KEG05135.1 - 2.7 8.7 34.1 1.4 9.6 28.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) T3SSipB PF16535.5 KEG05135.1 - 3.5 8.1 20.6 1.3e+02 3.0 20.6 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB PTS_IIA PF02255.16 KEG05135.1 - 8.8 6.5 13.0 0.15 12.1 3.2 2.4 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit TFIIA PF03153.13 KEG05136.1 - 0.074 13.0 7.9 0.079 13.0 7.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KEG05136.1 - 0.22 11.1 7.3 0.25 10.9 7.3 1.1 1 0 0 1 1 1 0 Spt20 family LRR_4 PF12799.7 KEG05138.1 - 1.3e-05 25.4 0.0 0.16 12.4 0.0 2.9 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG05138.1 - 7.1e-05 22.5 0.0 0.002 17.8 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 KEG05138.1 - 0.016 15.2 0.1 1.8 8.8 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LisH_TPL PF17814.1 KEG05138.1 - 0.083 12.6 0.2 17 5.2 0.0 2.5 2 0 0 2 2 2 0 LisH-like dimerisation domain COX5A PF02284.16 KEG05138.1 - 0.18 11.8 0.0 7.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va Ribosomal_L19e PF01280.20 KEG05139.1 - 0.018 15.1 1.6 0.023 14.8 1.6 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e LRRNT_2 PF08263.12 KEG05139.1 - 0.022 15.0 1.2 0.038 14.3 1.2 1.3 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Cep57_CLD_2 PF14197.6 KEG05140.1 - 2.3e-11 43.6 29.0 0.0089 16.1 2.2 4.1 1 1 3 4 4 4 4 Centrosome localisation domain of PPC89 Mto2_bdg PF12808.7 KEG05140.1 - 2.5e-07 30.9 18.5 0.34 11.2 0.2 4.3 4 0 0 4 4 4 4 Micro-tubular organiser Mto1 C-term Mto2-binding region MAP70 PF07058.11 KEG05140.1 - 1.5e-05 24.0 16.2 0.032 13.0 2.5 2.9 1 1 2 3 3 3 3 Microtubule-associated protein 70 YabA PF06156.13 KEG05140.1 - 5.5e-05 23.7 15.2 0.046 14.3 3.7 3.6 1 1 2 3 3 3 3 Initiation control protein YabA Shugoshin_N PF07558.11 KEG05140.1 - 8.6e-05 22.3 5.2 6.9 6.6 0.0 4.2 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Lebercilin PF15619.6 KEG05140.1 - 0.00015 21.4 19.8 0.017 14.8 15.3 2.9 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 KEG05140.1 - 0.00027 21.2 5.6 16 6.0 0.2 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KEG05140.1 - 0.00036 20.2 23.0 0.78 9.6 1.0 4.1 4 0 0 4 4 4 3 Septum formation initiator Spc7 PF08317.11 KEG05140.1 - 0.00063 18.7 17.8 0.00078 18.4 17.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Rab5-bind PF09311.11 KEG05140.1 - 0.0011 18.4 11.0 0.093 12.1 2.7 2.1 1 1 1 2 2 2 2 Rabaptin-like protein DUF4201 PF13870.6 KEG05140.1 - 0.0011 18.7 13.3 0.0016 18.2 5.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Rootletin PF15035.6 KEG05140.1 - 0.0016 18.5 19.0 0.12 12.4 7.5 2.4 1 1 2 3 3 3 3 Ciliary rootlet component, centrosome cohesion PhoU PF01895.19 KEG05140.1 - 0.0034 17.8 7.6 1.1 9.8 0.3 3.1 1 1 2 3 3 3 1 PhoU domain GAS PF13851.6 KEG05140.1 - 0.004 16.5 17.0 0.018 14.4 17.0 1.9 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 KEG05140.1 - 0.0065 16.2 11.7 0.22 11.2 11.8 2.0 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Seryl_tRNA_N PF02403.22 KEG05140.1 - 0.0068 16.6 16.2 0.29 11.4 1.6 3.3 1 1 2 3 3 3 2 Seryl-tRNA synthetase N-terminal domain TolA_bind_tri PF16331.5 KEG05140.1 - 0.0084 16.2 25.3 1.2 9.3 1.7 3.9 1 1 2 3 3 3 2 TolA binding protein trimerisation GIT_CC PF16559.5 KEG05140.1 - 0.011 15.5 7.9 20 5.1 0.0 4.0 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 KEG05140.1 - 0.014 16.0 35.3 0.18 12.3 15.1 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 KEG05140.1 - 0.015 15.7 30.1 0.75 10.3 12.5 2.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF3584 PF12128.8 KEG05140.1 - 0.018 12.6 20.6 0.033 11.7 20.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4972 PF16342.5 KEG05140.1 - 0.02 14.6 5.5 1.1 9.0 0.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4972) MEDS PF14417.6 KEG05140.1 - 0.029 14.2 4.6 0.71 9.7 0.9 2.2 1 1 1 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Sas6_CC PF18594.1 KEG05140.1 - 0.031 14.1 2.1 1.2e+02 2.5 0.0 4.6 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain Occludin_ELL PF07303.13 KEG05140.1 - 0.032 14.9 5.5 1.8 9.3 0.6 2.7 1 1 2 3 3 3 0 Occludin homology domain Catalase-rel PF06628.12 KEG05140.1 - 0.032 14.4 4.1 27 5.1 0.1 3.4 4 0 0 4 4 3 0 Catalase-related immune-responsive DUF948 PF06103.11 KEG05140.1 - 0.045 14.0 1.7 1.9 8.8 0.2 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sirohm_synth_C PF14823.6 KEG05140.1 - 0.046 13.4 4.6 58 3.4 0.1 4.0 4 0 0 4 4 4 0 Sirohaem biosynthesis protein C-terminal Rad52_Rad22 PF04098.15 KEG05140.1 - 0.065 13.1 0.3 19 5.1 0.1 2.9 1 1 2 3 3 3 0 Rad52/22 family double-strand break repair protein bZIP_2 PF07716.15 KEG05140.1 - 0.066 13.3 27.4 1.7 8.8 0.8 4.2 2 1 3 5 5 5 0 Basic region leucine zipper DUF1542 PF07564.11 KEG05140.1 - 0.069 13.3 14.9 1.8 8.7 1.4 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1542) PRKG1_interact PF15898.5 KEG05140.1 - 0.071 14.0 23.7 11 6.9 8.1 3.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF5304 PF17230.2 KEG05140.1 - 0.096 12.9 16.8 4.1 7.6 1.3 3.6 1 1 3 4 4 4 0 Family of unknown function (DUF5304) FliJ PF02050.16 KEG05140.1 - 0.099 12.9 18.4 0.45 10.8 12.1 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein SIKE PF05769.11 KEG05140.1 - 0.1 12.5 23.0 2.4 8.0 0.8 4.0 1 1 0 4 4 4 0 SIKE family Herpes_BLRF2 PF05812.12 KEG05140.1 - 0.12 12.6 17.8 7.5 6.7 0.5 4.1 1 1 3 4 4 4 0 Herpesvirus BLRF2 protein GHL13 PF14883.6 KEG05140.1 - 0.13 11.3 2.2 0.76 8.8 2.0 1.9 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 TPR_MLP1_2 PF07926.12 KEG05140.1 - 0.15 12.2 25.3 2 8.5 24.8 3.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein MCC-bdg_PDZ PF10506.9 KEG05140.1 - 0.17 11.9 13.1 7.6 6.6 0.4 3.6 1 1 2 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HOOK PF05622.12 KEG05140.1 - 0.21 9.7 19.4 1 7.4 19.4 2.0 1 1 0 1 1 1 0 HOOK protein WHEP-TRS PF00458.20 KEG05140.1 - 0.24 11.6 11.3 15 5.9 0.4 3.9 1 1 3 4 4 4 0 WHEP-TRS domain AHSP PF09236.10 KEG05140.1 - 0.27 11.7 13.1 8.8 6.9 0.5 3.6 1 1 3 4 4 3 0 Alpha-haemoglobin stabilising protein IFT57 PF10498.9 KEG05140.1 - 0.33 9.9 11.5 0.71 8.8 2.7 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Mod_r PF07200.13 KEG05140.1 - 0.33 11.0 17.1 0.57 10.3 5.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DASH_Dam1 PF08653.10 KEG05140.1 - 0.33 10.8 4.7 51 3.8 0.2 3.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 Atg14 PF10186.9 KEG05140.1 - 0.37 9.8 11.2 0.51 9.4 11.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FPP PF05911.11 KEG05140.1 - 0.41 8.8 15.1 0.32 9.1 5.0 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil TMPIT PF07851.13 KEG05140.1 - 0.43 9.8 4.8 0.19 11.0 2.0 1.4 1 1 1 2 2 2 0 TMPIT-like protein MetOD2 PF18548.1 KEG05140.1 - 0.43 10.7 10.6 5.8 7.1 0.6 3.0 1 1 2 3 3 3 0 Metanogen output domain 2 DUF848 PF05852.11 KEG05140.1 - 0.46 10.6 10.0 0.56 10.3 3.4 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Remorin_C PF03763.13 KEG05140.1 - 0.48 10.3 14.7 5.2 7.0 6.0 3.0 1 1 1 2 2 2 0 Remorin, C-terminal region DUF4407 PF14362.6 KEG05140.1 - 0.55 9.5 17.7 0.73 9.1 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 KEG05140.1 - 0.57 10.6 19.1 6.4 7.2 7.2 3.5 1 1 3 4 4 4 0 YlqD protein DUF812 PF05667.11 KEG05140.1 - 0.61 8.9 15.9 0.33 9.8 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KEG05140.1 - 0.67 10.4 16.4 1.6 9.2 16.4 1.6 1 1 0 1 1 1 0 Fez1 VPS38 PF17649.1 KEG05140.1 - 0.73 8.6 3.6 3 6.6 0.4 1.9 1 1 1 2 2 2 0 Vacuolar protein sorting 38 CENP-F_leu_zip PF10473.9 KEG05140.1 - 0.73 9.8 20.7 3.5 7.6 20.7 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF349 PF03993.12 KEG05140.1 - 0.82 10.0 21.0 0.66 10.3 6.9 2.3 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) HIP1_clath_bdg PF16515.5 KEG05140.1 - 1 10.0 20.5 6.4 7.5 5.0 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Jnk-SapK_ap_N PF09744.9 KEG05140.1 - 1.1 9.5 26.0 6.5 7.0 9.4 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 KEG05140.1 - 1.1 7.6 11.7 1.5 7.3 11.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG6 PF06419.11 KEG05140.1 - 1.3 7.2 7.7 3.1 5.9 1.3 1.9 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 DUF2381 PF09544.10 KEG05140.1 - 1.3 8.5 25.6 0.63 9.5 3.7 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF2381) Mce4_CUP1 PF11887.8 KEG05140.1 - 1.4 8.3 5.1 4.6 6.6 1.3 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Golgin_A5 PF09787.9 KEG05140.1 - 1.4 8.3 15.9 3.8 6.9 16.0 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 FH2 PF02181.23 KEG05140.1 - 1.6 7.8 9.5 0.81 8.7 2.1 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF4326 PF14216.6 KEG05140.1 - 1.6 9.5 4.5 21 5.9 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4326) FmiP_Thoc5 PF09766.9 KEG05140.1 - 1.8 7.7 11.5 5 6.3 3.5 2.3 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 ATG16 PF08614.11 KEG05140.1 - 2.3 8.4 26.0 49 4.1 26.2 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KEG05140.1 - 2.4 7.9 11.1 1.1 9.0 5.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spectrin PF00435.21 KEG05140.1 - 3 8.4 17.9 22 5.6 11.5 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF4200 PF13863.6 KEG05140.1 - 3 8.3 22.0 7.4 7.0 17.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V-SNARE PF05008.15 KEG05140.1 - 3.2 8.2 23.7 5.5 7.4 4.5 3.1 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BSD PF03909.17 KEG05140.1 - 3.2 7.8 8.5 72 3.5 0.1 4.3 4 1 0 4 4 4 0 BSD domain DUF4404 PF14357.6 KEG05140.1 - 3.2 8.4 20.9 9.1 7.0 6.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) CCDC-167 PF15188.6 KEG05140.1 - 3.3 8.1 20.8 12 6.3 1.1 4.0 1 1 3 4 4 4 0 Coiled-coil domain-containing protein 167 Vault PF01505.18 KEG05140.1 - 3.8 7.7 7.5 52 4.1 0.7 4.2 1 1 1 2 2 2 0 Major Vault Protein repeat domain KLRAQ PF10205.9 KEG05140.1 - 4.7 7.5 13.7 15 5.9 2.5 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4225 PF13988.6 KEG05140.1 - 4.8 6.7 5.8 52 3.3 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4225) V_ATPase_I PF01496.19 KEG05140.1 - 5.1 4.9 6.4 11 3.7 5.9 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 KEG05140.1 - 6.4 6.0 16.3 5.8 6.1 9.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 KEG05140.1 - 6.7 7.2 16.8 26 5.3 3.4 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KxDL PF10241.9 KEG05140.1 - 7.2 7.0 8.9 18 5.7 1.5 2.5 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF2388 PF09498.10 KEG05140.1 - 7.3 6.6 14.8 13 5.8 0.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2388) CorA PF01544.18 KEG05140.1 - 8.2 5.6 7.2 8.6 5.6 6.5 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 KEG05140.1 - 8.2 6.5 21.3 3.8 7.6 7.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KEG05140.1 - 9.4 6.9 19.4 12 6.6 1.3 3.9 1 1 3 4 4 4 0 SlyX eIF3_subunit PF08597.10 KEG05142.1 - 0.53 10.2 8.4 0.65 9.9 8.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit K_channel_TID PF07941.11 KEG05144.1 - 0.056 13.9 0.4 0.13 12.7 0.4 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain IFT57 PF10498.9 KEG05145.1 - 6.2e-07 28.7 8.5 0.00052 19.1 1.0 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 FPP PF05911.11 KEG05145.1 - 0.0012 17.1 19.3 0.025 12.8 7.6 1.9 1 1 1 2 2 2 2 Filament-like plant protein, long coiled-coil DUF5344 PF17279.2 KEG05145.1 - 0.029 14.9 5.5 1.7 9.3 0.5 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DMPK_coil PF08826.10 KEG05145.1 - 0.033 14.3 23.2 0.26 11.4 9.8 3.1 2 1 0 2 2 2 0 DMPK coiled coil domain like TFIIS_C PF01096.18 KEG05145.1 - 0.033 14.0 3.2 3 7.8 0.1 2.8 3 0 0 3 3 2 0 Transcription factor S-II (TFIIS) PEP-utilisers_N PF05524.13 KEG05145.1 - 0.048 13.8 7.8 0.075 13.2 7.6 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Blo-t-5 PF11642.8 KEG05145.1 - 0.05 13.6 5.3 0.59 10.1 2.5 2.3 1 1 1 2 2 2 0 Mite allergen Blo t 5 SesA PF17107.5 KEG05145.1 - 0.079 13.2 7.6 0.79 9.9 1.4 2.2 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Init_tRNA_PT PF04179.12 KEG05145.1 - 0.14 12.5 0.6 4.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Rit1 DUSP-like domain PI3K_P85_iSH2 PF16454.5 KEG05145.1 - 0.16 11.6 16.8 0.24 11.0 5.7 2.3 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sec2p PF06428.11 KEG05145.1 - 0.36 10.8 21.1 0.15 12.0 3.1 2.9 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p CENP-Q PF13094.6 KEG05145.1 - 0.76 10.0 29.6 0.077 13.2 8.9 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 KEG05145.1 - 1.2 8.1 12.6 2.7 7.0 12.6 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KEG05145.1 - 1.3 8.2 7.4 1.5 8.0 7.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 KEG05145.1 - 1.4 8.9 4.3 1.7 8.7 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 KEG05145.1 - 1.4 8.8 12.4 2.1 8.3 1.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit Spc29 PF17082.5 KEG05145.1 - 1.7 8.4 8.2 7.8 6.3 8.0 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 OmpH PF03938.14 KEG05145.1 - 1.9 8.8 14.8 0.79 10.1 3.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Rootletin PF15035.6 KEG05145.1 - 2.5 8.1 20.6 0.82 9.7 6.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion SOGA PF11365.8 KEG05145.1 - 3.3 8.9 20.0 2.4 9.3 6.2 2.1 1 1 1 2 2 2 0 Protein SOGA FlxA PF14282.6 KEG05145.1 - 3.8 7.5 17.0 5.1 7.2 6.3 2.3 1 1 1 2 2 2 0 FlxA-like protein VPS11_C PF12451.8 KEG05145.1 - 5 7.4 7.6 3.8 7.8 1.5 2.9 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal HAUS-augmin3 PF14932.6 KEG05145.1 - 6.5 6.3 21.8 32 4.0 21.5 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Swi5 PF07061.11 KEG05145.1 - 8.6 6.5 15.8 8.9 6.5 3.1 2.9 1 1 1 2 2 2 0 Swi5 DUF2564 PF10819.8 KEG05145.1 - 9.6 6.7 15.7 7.9 7.0 3.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) FeoB_C PF07664.12 KEG05146.1 - 7.2e-06 25.6 0.0 2.2 8.0 0.0 3.4 3 0 0 3 3 3 3 Ferrous iron transport protein B C terminus DUF4490 PF14892.6 KEG05146.1 - 0.054 13.5 0.1 42 4.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4490) Gsf2 PF11055.8 KEG05146.1 - 0.19 10.4 0.2 13 4.5 0.0 2.0 2 0 0 2 2 2 0 Glucose signalling factor 2 Peptidase_M8 PF01457.16 KEG05147.1 - 9e-27 93.9 3.6 9.5e-27 93.9 3.6 1.0 1 0 0 1 1 1 1 Leishmanolysin MTH865 PF07747.11 KEG05148.1 - 0.27 11.1 1.2 31 4.5 0.0 2.9 2 2 2 4 4 4 0 MTH865-like family Phage_holin_3_3 PF16083.5 KEG05148.1 - 0.31 11.2 14.4 5.3 7.2 1.6 3.8 3 1 0 3 3 3 0 LydA holin phage, holin superfamily III DUF1145 PF06611.12 KEG05148.1 - 0.41 10.7 41.2 0.95 9.5 8.9 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1145) Med13_C PF06333.12 KEG05150.1 - 0.043 13.1 0.9 0.047 13.0 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain NPL PF17800.1 KEG05150.1 - 0.052 14.1 0.1 0.066 13.8 0.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin-like domain Maf PF02545.14 KEG05150.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.4 1 1 0 1 1 1 0 Maf-like protein Guanylate_cyc PF00211.20 KEG05151.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Alanine_zipper PF11839.8 KEG05152.1 - 0.0068 16.7 31.3 0.76 10.2 1.1 3.2 2 1 1 3 3 3 3 Alanine-zipper, major outer membrane lipoprotein GARP PF16731.5 KEG05152.1 - 0.89 9.2 25.1 7.4 6.2 23.4 2.2 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DFF-C PF09033.10 KEG05158.1 - 0.33 10.9 6.9 0.4 10.6 6.9 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Histone_HNS PF00816.21 KEG05158.1 - 0.64 10.9 11.2 0.19 12.6 1.6 2.2 1 1 1 2 2 2 0 H-NS histone family TMPIT PF07851.13 KEG05158.1 - 1 8.6 2.3 1.2 8.3 2.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 KEG05158.1 - 1.3 7.5 6.0 1.4 7.4 6.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4337 PF14235.6 KEG05158.1 - 3.1 7.9 6.7 4.7 7.3 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HATPase_c_2 PF13581.6 KEG05159.1 - 0.093 12.7 0.3 0.12 12.3 0.3 1.4 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain HicB-like_2 PF15970.5 KEG05159.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 1 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Galactosyl_T PF01762.21 KEG05162.1 - 2.1e-05 24.5 0.1 0.087 12.6 0.0 2.8 1 1 1 3 3 3 2 Galactosyltransferase PEX11 PF05648.14 KEG05162.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.24 KEG05164.1 - 8.8e-14 51.2 0.5 8.8e-14 51.2 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEG05164.1 - 0.00035 19.6 5.3 0.00043 19.3 5.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PSI PF01437.25 KEG05164.1 - 0.0037 17.8 8.8 0.098 13.2 0.9 2.2 1 1 1 2 2 2 2 Plexin repeat BT1 PF03092.16 KEG05164.1 - 0.05 11.8 2.6 0.077 11.2 2.6 1.2 1 0 0 1 1 1 0 BT1 family Paramecium_SA PF01508.16 KEG05164.1 - 0.31 11.5 13.5 0.24 11.8 6.5 2.3 1 1 0 1 1 1 0 Paramecium surface antigen domain Mucin PF01456.17 KEG05165.1 - 0.00065 19.7 22.6 0.0011 19.0 22.5 1.4 1 1 0 1 1 1 1 Mucin-like glycoprotein NPL4 PF05021.15 KEG05166.1 - 0.044 13.1 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 NPL4 family Nodulin-like PF06813.13 KEG05172.1 - 3.5e-09 36.5 6.0 4e-09 36.3 6.0 1.0 1 0 0 1 1 1 1 Nodulin-like Gram_pos_anchor PF00746.21 KEG05172.1 - 3.1 7.8 4.7 7.4 6.6 4.7 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CDC27 PF09507.10 KEG05173.1 - 0.06 12.7 14.7 0.073 12.4 14.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cep57_CLD PF14073.6 KEG05173.1 - 0.2 11.7 13.6 0.022 14.8 8.7 1.6 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 BRE1 PF08647.11 KEG05173.1 - 0.62 10.2 15.1 0.057 13.5 5.9 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KEG05173.1 - 0.77 10.2 15.4 1.9 8.9 15.4 1.6 1 1 0 1 1 1 0 Fez1 Dynactin_p22 PF07426.11 KEG05173.1 - 1 9.2 7.4 1.7 8.5 7.4 1.4 1 1 0 1 1 1 0 Dynactin subunit p22 ERM PF00769.19 KEG05173.1 - 1.9 8.2 21.9 2.2 8.0 21.3 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 KEG05173.1 - 2.7 8.3 17.4 2.7 8.3 10.7 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 KEG05173.1 - 5.5 7.4 17.2 0.92 9.9 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) KELK PF15796.5 KEG05173.1 - 7.2 7.1 13.3 0.54 10.7 3.0 2.5 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2870 PF11069.8 KEG05173.1 - 7.8 7.0 8.8 1.5 9.3 1.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2870) PALP PF00291.25 KEG05175.1 - 1.2e-08 34.7 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FLYWCH PF04500.16 KEG05177.1 - 0.034 14.2 0.5 0.058 13.5 0.5 1.4 1 0 0 1 1 1 0 FLYWCH zinc finger domain XRN_N PF03159.18 KEG05178.1 - 2.8e-08 33.5 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus LRR_4 PF12799.7 KEG05179.1 - 2.5e-11 43.6 0.0 0.076 13.5 0.0 4.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG05179.1 - 3.5e-06 26.6 4.7 0.52 10.5 0.1 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 KEG05179.1 - 2.9e-05 23.7 0.1 1.1 9.0 0.0 4.0 1 1 3 4 4 4 4 Leucine rich repeat TrbL PF04610.14 KEG05180.1 - 0.015 15.1 0.3 0.019 14.8 0.3 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein CD34_antigen PF06365.12 KEG05180.1 - 0.031 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF202 PF02656.15 KEG05180.1 - 0.042 14.3 1.5 0.097 13.1 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF3246 PF11596.8 KEG05180.1 - 0.042 13.3 0.2 0.067 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DAP10 PF07213.11 KEG05180.1 - 0.047 13.6 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 DAP10 membrane protein DUF4690 PF15756.5 KEG05180.1 - 0.049 14.2 0.1 0.076 13.6 0.1 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 KEG05180.1 - 0.06 14.2 0.1 0.1 13.5 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KEG05180.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF309 PF03745.14 KEG05180.1 - 0.16 11.7 0.1 0.4 10.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF309) S1FA PF04689.13 KEG05180.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA Peptidase_M8 PF01457.16 KEG05184.1 - 1.7e-08 33.7 0.0 2.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin TFIIA PF03153.13 KEG05186.1 - 0.26 11.2 9.5 0.33 10.9 9.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GARP PF16731.5 KEG05186.1 - 0.39 10.4 37.1 0.5 10.0 17.0 2.2 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Alanine_zipper PF11839.8 KEG05186.1 - 6.7 7.2 46.8 8.3 6.9 6.5 3.7 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Peptidase_M8 PF01457.16 KEG05188.1 - 4.1e-41 141.3 1.9 4.5e-41 141.1 1.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 KEG05190.1 - 8.1e-33 113.9 4.9 8.9e-33 113.8 4.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Penicil_amidase PF01804.18 KEG05191.1 - 5.3e-39 134.7 0.0 6.1e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase Voltage_CLC PF00654.20 KEG05195.1 - 0.05 12.8 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel MetOD2 PF18548.1 KEG05198.1 - 0.0093 16.0 4.8 0.44 10.7 0.6 2.7 3 0 0 3 3 3 2 Metanogen output domain 2 ADIP PF11559.8 KEG05198.1 - 0.035 14.2 9.1 0.18 11.9 0.7 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 KEG05198.1 - 0.05 13.5 6.8 0.22 11.4 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.8 KEG05198.1 - 0.2 11.9 11.8 0.94 9.7 0.8 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 KEG05198.1 - 0.28 11.5 9.0 5.3 7.5 0.7 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KEG05198.1 - 0.65 10.3 13.3 0.31 11.3 1.9 3.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain ATG16 PF08614.11 KEG05198.1 - 0.74 10.0 13.9 1.4 9.1 6.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Filament PF00038.21 KEG05198.1 - 1.1 8.7 9.6 0.076 12.6 2.4 1.9 2 0 0 2 2 2 0 Intermediate filament protein FadA PF09403.10 KEG05198.1 - 1.2 9.6 7.1 15 6.2 0.0 3.4 3 1 0 3 3 3 0 Adhesion protein FadA CENP-F_leu_zip PF10473.9 KEG05198.1 - 1.2 9.1 8.3 2.9 7.9 2.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 KEG05198.1 - 1.8 9.0 8.4 1.4 9.4 2.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Cep57_MT_bd PF06657.13 KEG05198.1 - 2.8 8.4 8.5 7.7 7.1 2.1 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AAA_lid_3 PF17862.1 KEG05198.1 - 3.2 7.7 7.7 19 5.2 0.8 2.8 2 0 0 2 2 2 0 AAA+ lid domain DASH_Spc19 PF08287.11 KEG05198.1 - 4.8 7.1 8.3 0.96 9.3 0.3 2.2 1 1 0 2 2 2 0 Spc19 Peripla_BP_3 PF13377.6 KEG05198.1 - 5.6 7.3 9.8 12 6.2 0.4 2.8 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Mucin PF01456.17 KEG05199.1 - 0.0015 18.5 15.8 0.0028 17.6 15.8 1.5 1 1 0 1 1 1 1 Mucin-like glycoprotein ATP-synt_B PF00430.18 KEG05199.1 - 0.02 15.0 5.6 0.027 14.6 5.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ribosomal_L22 PF00237.19 KEG05199.1 - 0.21 11.8 2.8 0.34 11.2 2.8 1.4 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e DUF883 PF05957.13 KEG05199.1 - 0.26 11.9 8.2 3.3 8.4 3.4 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Macoilin PF09726.9 KEG05199.1 - 0.54 8.7 4.4 0.64 8.5 4.4 1.1 1 0 0 1 1 1 0 Macoilin family PTS_IIA PF02255.16 KEG05199.1 - 7.6 6.7 8.2 12 6.1 3.9 2.2 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Alanine_zipper PF11839.8 KEG05199.1 - 7.8 7.0 20.6 0.74 10.2 15.6 1.9 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF1465 PF07323.12 KEG05201.1 - 3.4e-06 27.0 4.5 0.0019 18.0 1.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1465) CtIP_N PF10482.9 KEG05201.1 - 0.00011 22.2 11.0 0.0056 16.7 5.8 3.0 2 1 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain Nnf1 PF03980.14 KEG05201.1 - 0.00032 21.0 8.4 0.0025 18.2 1.6 3.1 1 1 2 3 3 3 2 Nnf1 DUF4200 PF13863.6 KEG05201.1 - 0.00052 20.4 4.2 0.17 12.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) LRRFIP PF09738.9 KEG05201.1 - 0.00059 19.4 7.0 0.032 13.7 2.0 2.2 2 0 0 2 2 2 2 LRRFIP family Golgin_A5 PF09787.9 KEG05201.1 - 0.001 18.6 9.9 0.0019 17.7 4.8 2.0 2 0 0 2 2 2 1 Golgin subfamily A member 5 Cep57_MT_bd PF06657.13 KEG05201.1 - 0.0036 17.7 7.8 0.49 10.9 0.6 3.1 2 1 1 3 3 3 3 Centrosome microtubule-binding domain of Cep57 ZapB PF06005.12 KEG05201.1 - 0.0037 17.7 11.3 0.26 11.7 0.0 2.7 2 1 1 3 3 3 2 Cell division protein ZapB bZIP_1 PF00170.21 KEG05201.1 - 0.0065 16.6 6.6 0.56 10.3 0.6 2.5 2 0 0 2 2 2 2 bZIP transcription factor HOOK PF05622.12 KEG05201.1 - 0.013 13.7 6.1 0.086 11.0 1.9 2.0 2 0 0 2 2 2 0 HOOK protein DUF4407 PF14362.6 KEG05201.1 - 0.018 14.4 3.3 0.041 13.2 2.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FmiP_Thoc5 PF09766.9 KEG05201.1 - 0.023 14.0 1.7 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 FTA4 PF13093.6 KEG05201.1 - 0.03 14.2 2.1 2.7 7.9 0.6 2.1 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Snapin_Pallidin PF14712.6 KEG05201.1 - 0.035 14.5 1.1 8.8 6.8 0.1 2.5 3 0 0 3 3 2 0 Snapin/Pallidin Cortex-I_coil PF09304.10 KEG05201.1 - 0.042 14.1 9.3 1.1 9.5 4.4 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil Spc24 PF08286.11 KEG05201.1 - 0.044 14.0 5.6 2.5 8.4 1.0 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Tektin PF03148.14 KEG05201.1 - 0.046 12.5 3.1 2.3 6.9 0.4 2.2 2 0 0 2 2 2 0 Tektin family CENP-F_leu_zip PF10473.9 KEG05201.1 - 0.051 13.6 15.6 2.2 8.3 9.6 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 KEG05201.1 - 0.051 13.0 8.8 1.6 8.1 0.2 2.3 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KEG05201.1 - 0.072 13.3 12.3 0.28 11.4 0.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fibrinogen_aC PF12160.8 KEG05201.1 - 0.1 12.4 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha C domain ADIP PF11559.8 KEG05201.1 - 0.11 12.6 6.7 0.84 9.7 1.7 2.4 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 KEG05201.1 - 0.11 12.7 4.1 5.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 KEG05201.1 - 0.12 12.6 6.6 4.3 7.5 4.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Ax_dynein_light PF10211.9 KEG05201.1 - 0.12 12.3 6.2 0.74 9.7 2.0 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain zf-CpG_bind_C PF12269.8 KEG05201.1 - 0.13 12.1 1.8 0.45 10.3 0.7 1.9 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF4472 PF14739.6 KEG05201.1 - 0.14 12.9 5.9 5.5 7.8 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) AAA_13 PF13166.6 KEG05201.1 - 0.17 10.5 0.7 5.8 5.4 0.3 2.0 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.8 KEG05201.1 - 0.17 11.1 2.3 6.9 5.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 KEG05201.1 - 0.19 11.4 9.8 3.6 7.2 3.8 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 KEG05201.1 - 0.2 11.4 7.7 3.1 7.6 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 KEG05201.1 - 0.35 11.1 8.8 1.3 9.2 0.5 2.7 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 KEG05201.1 - 0.37 11.0 7.3 2.2 8.5 1.8 2.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF3037 PF11236.8 KEG05201.1 - 0.41 11.1 3.1 1.2 9.6 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) KELK PF15796.5 KEG05201.1 - 0.55 10.7 7.3 4.8 7.7 0.1 2.6 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RmuC PF02646.16 KEG05201.1 - 0.63 9.1 2.7 2.3 7.3 1.2 2.0 2 0 0 2 2 2 0 RmuC family FlaC_arch PF05377.11 KEG05201.1 - 0.7 10.3 6.4 14 6.2 0.1 3.5 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) Rho_Binding PF08912.11 KEG05201.1 - 0.75 10.7 6.5 5.1 8.0 0.6 2.7 3 0 0 3 3 2 0 Rho Binding M PF02370.16 KEG05201.1 - 0.75 10.5 24.9 14 6.6 0.3 5.9 5 1 1 6 6 6 0 M protein repeat Cep57_CLD PF14073.6 KEG05201.1 - 0.79 9.7 12.1 4.1 7.4 7.5 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of Cep57 Atg14 PF10186.9 KEG05201.1 - 0.9 8.6 4.9 5 6.1 2.6 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 KEG05201.1 - 0.93 9.0 3.5 0.83 9.2 0.9 1.8 2 0 0 2 2 2 0 TMCO5 family Prefoldin_2 PF01920.20 KEG05201.1 - 1 9.4 6.9 10 6.2 0.8 2.7 2 1 0 2 2 2 0 Prefoldin subunit Flagellar_rod PF05149.12 KEG05201.1 - 1.2 8.6 6.2 0.61 9.5 1.9 1.9 2 0 0 2 2 2 0 Paraflagellar rod protein Mei5 PF10376.9 KEG05201.1 - 1.3 8.8 6.5 3.2 7.6 0.7 2.1 2 0 0 2 2 2 0 Double-strand recombination repair protein APG6_N PF17675.1 KEG05201.1 - 1.3 9.5 18.7 0.57 10.7 1.4 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 KEG05201.1 - 1.4 9.3 6.1 11 6.5 3.0 2.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 KEG05201.1 - 1.5 8.9 17.7 2.1 8.4 2.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PspB PF06667.12 KEG05201.1 - 1.5 8.9 8.5 7.4 6.7 1.0 2.4 2 0 0 2 2 2 0 Phage shock protein B Rx_N PF18052.1 KEG05201.1 - 1.5 9.1 5.3 1.9 8.8 0.1 2.4 2 1 0 2 2 2 0 Rx N-terminal domain Med21 PF11221.8 KEG05201.1 - 1.7 8.9 18.7 2.8 8.2 3.0 3.0 2 1 1 3 3 3 0 Subunit 21 of Mediator complex SWIRM-assoc_1 PF16495.5 KEG05201.1 - 1.9 8.5 9.3 6.8 6.7 0.7 2.4 2 0 0 2 2 2 0 SWIRM-associated region 1 MRF_C1 PF13887.6 KEG05201.1 - 4.4 6.6 10.0 22 4.3 0.1 4.4 5 0 0 5 5 5 0 Myelin gene regulatory factor -C-terminal domain 1 ERM PF00769.19 KEG05201.1 - 5.4 6.8 15.9 4.6 7.0 0.2 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4164 PF13747.6 KEG05201.1 - 5.9 7.2 19.0 1.7 8.9 2.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) kleA_kleC PF17383.2 KEG05201.1 - 6.1 7.2 8.0 27 5.2 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A SlyX PF04102.12 KEG05201.1 - 6.4 7.5 10.1 50 4.6 0.1 3.7 2 2 1 3 3 3 0 SlyX Tropomyosin_1 PF12718.7 KEG05201.1 - 7.3 6.7 17.5 8.4 6.5 0.9 2.8 2 1 0 2 2 2 0 Tropomyosin like HALZ PF02183.18 KEG05201.1 - 8.7 6.7 9.3 4.1 7.7 0.7 2.7 3 0 0 3 3 2 0 Homeobox associated leucine zipper Methyltransf_31 PF13847.6 KEG05202.1 - 0.00017 21.4 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG05202.1 - 0.00072 20.2 0.0 0.0018 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG05202.1 - 0.002 18.8 0.0 0.0043 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KEG05202.1 - 0.0065 16.1 0.0 0.01 15.5 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 KEG05202.1 - 0.0088 16.8 0.0 0.013 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KEG05202.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Peptidase_M8 PF01457.16 KEG05203.1 - 7.1e-32 110.8 0.0 8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peripla_BP_6 PF13458.6 KEG05204.1 - 7.3e-06 25.9 0.0 8.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Kre28 PF17097.5 KEG05206.1 - 4.2e-08 32.6 5.2 0.0012 17.9 0.3 2.3 3 0 0 3 3 3 2 Spindle pole body component Osmo_CC PF08946.10 KEG05206.1 - 0.013 15.7 3.2 4.6 7.6 0.2 3.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Paz_1 PF18349.1 KEG05206.1 - 0.024 14.6 0.9 53 3.9 0.0 3.2 3 0 0 3 3 3 0 PAZ domain Herpes_UL37_1 PF03970.13 KEG05206.1 - 0.087 12.0 0.1 16 4.5 0.0 2.7 2 1 1 3 3 3 0 Herpesvirus UL37 tegument protein YlqD PF11068.8 KEG05206.1 - 0.11 12.8 4.6 6 7.2 0.3 2.2 2 0 0 2 2 2 0 YlqD protein DUF2934 PF11154.8 KEG05206.1 - 0.2 11.3 5.5 30 4.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2934) DinB PF05163.12 KEG05206.1 - 0.38 10.7 3.7 4.7 7.1 0.3 2.4 1 1 1 2 2 2 0 DinB family DUF2533 PF10752.9 KEG05206.1 - 0.9 10.0 8.2 7.4 7.1 0.6 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF2533) FKBP_N PF01346.18 KEG05206.1 - 2.1 9.4 14.1 15 6.6 1.1 3.4 3 2 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TAF8_C PF10406.9 KEG05206.1 - 5.8 7.6 10.0 57 4.4 0.8 3.6 3 1 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term Peptidase_M8 PF01457.16 KEG05212.1 - 3.3e-50 171.3 0.0 3.6e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin ABC2_membrane_3 PF12698.7 KEG05213.1 - 4.8e-27 95.0 14.8 5.4e-27 94.8 14.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein LPG_synthase_TM PF03706.13 KEG05213.1 - 0.05 13.1 12.9 0.014 15.0 8.2 1.8 1 1 1 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DUF1129 PF06570.11 KEG05213.1 - 0.086 12.3 4.5 0.12 11.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3021 PF11457.8 KEG05213.1 - 0.27 11.6 11.3 0.2 12.0 9.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) NuA4 PF09340.10 KEG05216.1 - 0.17 11.8 3.2 0.87 9.5 3.2 2.2 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 G_path_suppress PF15991.5 KEG05216.1 - 0.33 11.0 6.6 0.4 10.8 6.6 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Abhydrolase_3 PF07859.13 KEG05219.1 - 1.6e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KEG05219.1 - 0.024 14.3 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4611 PF15387.6 KEG05219.1 - 0.072 13.3 2.0 0.11 12.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Abhydrolase_6 PF12697.7 KEG05219.1 - 0.11 13.1 0.7 0.17 12.5 0.2 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family SR-25 PF10500.9 KEG05222.1 - 0.00041 20.0 3.0 0.00048 19.8 3.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.13 KEG05222.1 - 0.0014 18.6 3.1 0.0016 18.4 3.1 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF3446 PF11928.8 KEG05222.1 - 0.0025 18.1 3.5 0.0041 17.4 3.5 1.4 1 0 0 1 1 1 1 Early growth response N-terminal domain BNIP3 PF06553.12 KEG05222.1 - 0.05 13.3 5.6 0.064 12.9 5.6 1.1 1 0 0 1 1 1 0 BNIP3 DUF4834 PF16118.5 KEG05222.1 - 0.054 14.5 2.5 0.077 14.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 KEG05222.1 - 0.062 13.7 6.4 0.08 13.4 6.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4820 PF16091.5 KEG05222.1 - 0.2 11.0 1.8 0.24 10.7 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 KEG05222.1 - 0.22 9.8 4.6 0.24 9.7 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KEG05222.1 - 0.28 11.0 4.7 0.31 10.8 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.14 KEG05222.1 - 0.89 8.9 14.0 1.1 8.6 14.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region V_ATPase_I PF01496.19 KEG05222.1 - 1 7.2 3.9 1 7.2 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 KEG05222.1 - 1.3 7.7 7.8 1.5 7.5 7.8 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KEG05222.1 - 1.3 8.1 7.2 1.4 8.0 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 KEG05222.1 - 1.6 8.7 3.4 1.6 8.8 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.6 KEG05222.1 - 2.6 7.7 5.7 3.2 7.4 5.7 1.2 1 0 0 1 1 1 0 FAM176 family Pex14_N PF04695.13 KEG05222.1 - 4.9 7.8 11.7 7.5 7.2 11.6 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KEG05222.1 - 5 6.7 16.0 6.4 6.3 16.0 1.1 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 KEG05222.1 - 5.3 5.0 5.3 5.3 5.0 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PBP_sp32 PF07222.12 KEG05222.1 - 7.9 5.9 11.9 10 5.5 11.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ELO PF01151.18 KEG05223.1 - 1.9e-30 106.2 8.9 2.1e-30 106.1 8.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PsbL PF02419.17 KEG05223.1 - 0.05 13.6 0.3 0.05 13.6 0.3 1.9 2 0 0 2 2 2 0 PsbL protein Insulin_TMD PF17870.1 KEG05223.1 - 0.51 10.4 5.7 2.3 8.4 3.2 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment RRM_1 PF00076.22 KEG05227.1 - 9.9e-10 38.1 0.2 0.0017 18.1 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEG05227.1 - 5.7e-05 23.0 0.9 0.00017 21.5 0.9 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEG05227.1 - 0.0072 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif DUF1533 PF07550.11 KEG05228.1 - 0.11 12.3 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) DUF202 PF02656.15 KEG05230.1 - 0.054 13.9 1.2 0.097 13.1 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) S1FA PF04689.13 KEG05230.1 - 0.062 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4690 PF15756.5 KEG05230.1 - 0.065 13.8 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage VSP PF03302.13 KEG05230.1 - 0.51 9.1 2.4 0.43 9.4 0.5 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein TRAM_LAG1_CLN8 PF03798.16 KEG05231.1 - 2.5e-08 33.9 11.7 3e-08 33.7 11.7 1.1 1 0 0 1 1 1 1 TLC domain DUF2873 PF11395.8 KEG05231.1 - 0.028 14.3 3.8 0.028 14.3 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) MMPL PF03176.15 KEG05231.1 - 0.19 10.7 6.4 0.23 10.3 6.4 1.1 1 0 0 1 1 1 0 MMPL family G3P_acyltransf PF02660.15 KEG05231.1 - 0.78 9.8 8.8 1 9.4 8.8 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Mucin PF01456.17 KEG05232.1 - 0.00035 20.6 19.7 0.00035 20.6 19.7 2.1 1 1 1 2 2 2 1 Mucin-like glycoprotein MAM33 PF02330.16 KEG05232.1 - 0.066 13.2 1.8 0.098 12.6 1.8 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein DUF2062 PF09835.9 KEG05234.1 - 0.033 14.0 2.8 0.039 13.8 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Polysacc_deac_3 PF15421.6 KEG05234.1 - 0.11 11.0 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase DUF3487 PF11990.8 KEG05234.1 - 0.18 11.7 4.0 0.22 11.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF677 PF05055.12 KEG05234.1 - 7.2 5.4 6.2 7.5 5.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Mucin PF01456.17 KEG05236.1 - 0.067 13.2 0.1 0.082 12.9 0.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2457 PF10446.9 KEG05239.1 - 0.054 12.6 12.4 0.055 12.6 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IFT57 PF10498.9 KEG05239.1 - 0.14 11.1 4.2 0.17 10.9 4.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDC45 PF02724.14 KEG05239.1 - 0.38 9.0 6.9 0.37 9.0 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 KEG05239.1 - 2.6 6.9 11.6 2.7 6.8 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RRN3 PF05327.11 KEG05239.1 - 3.4 6.1 6.8 3.3 6.2 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KEG05239.1 - 4.2 5.5 9.3 4.3 5.4 9.3 1.0 1 0 0 1 1 1 0 Nop14-like family Got1 PF04178.12 KEG05241.1 - 3e-32 111.4 16.4 3.5e-32 111.2 16.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KEG05241.1 - 1.9 6.7 11.8 2.1 6.5 11.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4064 PF13273.6 KEG05241.1 - 4.9 7.5 13.8 84 3.5 13.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) TRAP_alpha PF03896.16 KEG05243.1 - 0.17 11.1 0.1 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit GREB1 PF15782.5 KEG05243.1 - 3.1 4.8 9.6 3.4 4.7 9.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ank_5 PF13857.6 KEG05244.1 - 0.0049 17.2 0.1 0.28 11.5 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Amastin PF07344.11 KEG05247.1 - 3.5e-20 72.4 8.8 4.2e-20 72.2 8.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KEG05247.1 - 0.00046 20.1 4.5 0.00065 19.6 4.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF1616 PF07760.11 KEG05247.1 - 0.001 18.5 0.6 0.002 17.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) OST3_OST6 PF04756.13 KEG05247.1 - 0.012 15.0 0.5 0.012 15.0 0.5 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family D-ser_dehydrat PF14031.6 KEG05247.1 - 0.16 12.6 0.5 24 5.6 0.1 2.7 3 0 0 3 3 3 0 Putative serine dehydratase domain UL41A PF17591.2 KEG05252.1 - 0.072 13.2 0.1 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL41A UCH PF00443.29 KEG05255.1 - 0.29 10.6 1.1 4.7 6.6 0.8 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Amastin PF07344.11 KEG05257.1 - 1.8e-06 27.9 2.9 1.9e-06 27.8 2.3 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein HIG_1_N PF04588.13 KEG05257.1 - 0.00062 19.9 1.2 1.3 9.3 0.1 2.5 2 0 0 2 2 2 2 Hypoxia induced protein conserved region DUF1660 PF07874.11 KEG05260.1 - 1.5 9.3 3.8 16 6.1 0.6 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) zf_C2H2_13 PF18508.1 KEG05260.1 - 7.8 6.2 5.5 10 5.8 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain Endomucin PF07010.12 KEG05261.1 - 0.27 11.2 10.6 0.32 10.9 10.6 1.2 1 0 0 1 1 1 0 Endomucin PHC2_SAM_assoc PF16616.5 KEG05261.1 - 0.99 10.2 10.9 2.1 9.2 9.1 2.2 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 GREB1 PF15782.5 KEG05261.1 - 2.1 5.3 12.7 2.4 5.1 12.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 KEG05261.1 - 9.8 4.7 11.6 13 4.3 11.6 1.1 1 0 0 1 1 1 0 Hamartin protein SAPS PF04499.15 KEG05261.1 - 9.9 4.8 7.9 11 4.7 7.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Guanylate_cyc PF00211.20 KEG05262.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 KEG05262.1 - 0.021 14.5 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Adeno_E3_CR2 PF02439.15 KEG05262.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KEG05262.1 - 0.24 11.3 0.3 0.43 10.5 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain DIMCO_N PF16844.5 KEG05263.1 - 0.18 12.2 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Mucin PF01456.17 KEG05264.1 - 0.28 11.1 19.0 1.4 8.9 19.0 2.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Hid1 PF12722.7 KEG05264.1 - 0.29 9.2 2.0 0.32 9.1 2.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.6 KEG05264.1 - 0.33 9.6 5.9 0.39 9.4 5.9 1.1 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.11 KEG05264.1 - 0.62 9.6 5.1 0.68 9.5 5.1 1.2 1 0 0 1 1 1 0 PPP4R2 SRP-alpha_N PF04086.13 KEG05264.1 - 8.2 6.3 13.8 9.6 6.0 13.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Asp4 PF16996.5 KEG05265.1 - 0.0077 16.0 0.0 0.035 13.9 0.1 1.8 2 0 0 2 2 2 1 Accessory secretory protein Sec Asp4 KMP11 PF03037.16 KEG05266.1 - 2.1e-56 188.7 17.5 2.3e-56 188.5 17.5 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 KEG05266.1 - 0.0021 18.0 2.2 0.0062 16.4 2.2 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 KEG05266.1 - 0.021 14.7 4.8 0.022 14.6 4.8 1.0 1 0 0 1 1 1 0 PIN like domain Lyase_8_N PF08124.11 KEG05266.1 - 0.022 13.7 1.3 0.022 13.7 1.3 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain ZnuA PF01297.17 KEG05266.1 - 0.024 14.1 3.4 0.35 10.3 0.2 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic FCH PF00611.23 KEG05266.1 - 0.049 13.9 2.5 0.17 12.2 2.5 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain T5orf172 PF10544.9 KEG05266.1 - 0.056 14.0 2.7 0.069 13.7 2.7 1.2 1 0 0 1 1 1 0 T5orf172 domain TipAS PF07739.13 KEG05266.1 - 0.073 13.6 6.4 0.17 12.4 0.8 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF3987 PF13148.6 KEG05266.1 - 0.18 10.8 1.8 0.22 10.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2990 PF11693.8 KEG05266.1 - 0.26 11.5 1.2 3 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2990) Metal_resist PF13801.6 KEG05266.1 - 0.28 11.4 1.0 2.5 8.3 0.1 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Adhesin_P1_N PF18652.1 KEG05266.1 - 0.66 10.0 3.4 4.3 7.4 0.5 2.2 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain CLZ PF16526.5 KEG05266.1 - 0.7 10.3 5.0 23 5.5 5.1 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Amidase PF01425.21 KEG05266.1 - 0.87 8.5 2.5 0.95 8.3 2.5 1.0 1 0 0 1 1 1 0 Amidase baeRF_family5 PF18846.1 KEG05266.1 - 1.8 8.7 8.0 1.9 8.7 4.7 1.9 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 DUF2884 PF11101.8 KEG05266.1 - 1.9 8.0 7.7 6 6.3 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF2130 PF09903.9 KEG05266.1 - 2.3 7.4 14.0 0.64 9.2 6.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) SCVP PF17619.2 KEG05266.1 - 2.4 9.1 5.2 1.5 9.7 1.5 2.0 1 1 1 2 2 2 0 Secreted clade V proteins Muted PF14942.6 KEG05266.1 - 2.8 8.3 13.4 28 5.0 13.4 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein YtxH PF12732.7 KEG05266.1 - 3 8.4 4.9 15 6.2 4.9 1.9 1 1 0 1 1 1 0 YtxH-like protein OmpH PF03938.14 KEG05266.1 - 3.2 8.1 11.7 7.8 6.8 11.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) INSC_LBD PF16748.5 KEG05267.1 - 0.093 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Inscuteable LGN-binding domain YlbD_coat PF14071.6 KEG05270.1 - 0.048 13.9 0.0 0.082 13.2 0.0 1.4 1 1 0 1 1 1 0 Putative coat protein FliG_C PF01706.16 KEG05270.1 - 0.084 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 FliG C-terminal domain Mucin PF01456.17 KEG05270.1 - 3.6 7.6 8.7 12 5.8 8.7 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein Neur_chan_memb PF02932.16 KEG05272.1 - 0.11 12.5 1.3 0.14 12.2 1.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 KEG05272.1 - 4.2 7.1 8.4 4.8 6.9 8.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 KEG05272.1 - 6.1 7.9 8.2 15 6.6 8.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ac76 PF05814.11 KEG05274.1 - 0.049 13.6 0.0 4.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) DUF3357 PF11837.8 KEG05274.1 - 0.083 13.4 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) XRCC4 PF06632.12 KEG05279.1 - 0.004 16.1 3.6 0.005 15.7 3.0 1.5 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Vps5 PF09325.10 KEG05279.1 - 0.0071 15.9 6.1 0.0086 15.6 6.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like TolA_bind_tri PF16331.5 KEG05279.1 - 0.041 14.0 10.7 0.12 12.5 1.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Uso1_p115_C PF04871.13 KEG05279.1 - 0.048 14.0 20.0 0.057 13.8 15.3 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 KEG05279.1 - 0.12 11.5 11.4 0.15 11.2 11.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KEG05279.1 - 0.16 12.6 9.8 0.36 11.5 4.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 KEG05279.1 - 0.18 12.3 2.6 5.4 7.5 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 KEG05279.1 - 0.32 11.4 11.9 0.74 10.2 4.1 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain KASH_CCD PF14662.6 KEG05279.1 - 0.34 10.7 15.3 2 8.2 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 KEG05279.1 - 0.35 11.1 9.0 0.42 10.9 1.3 3.3 3 0 0 3 3 2 0 Homeobox associated leucine zipper Spc7 PF08317.11 KEG05279.1 - 0.49 9.2 15.2 1 8.2 15.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KEG05279.1 - 1.2 8.9 17.9 0.7 9.7 6.1 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 KEG05279.1 - 1.2 9.2 6.1 1.8 8.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KEG05279.1 - 1.3 9.1 12.7 3.2 7.8 12.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 KEG05279.1 - 1.5 9.0 10.3 7.9 6.7 0.4 2.6 2 0 0 2 2 2 0 bZIP transcription factor Cnn_1N PF07989.11 KEG05279.1 - 1.6 9.0 10.7 7.6 6.8 9.5 2.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 KEG05279.1 - 1.8 8.7 16.1 1.2 9.2 11.1 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 KEG05279.1 - 1.8 8.0 18.3 1 8.9 11.5 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 KEG05279.1 - 2.1 7.6 10.5 2.9 7.2 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 KEG05279.1 - 2.7 8.4 12.6 4.4 7.6 7.6 2.5 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3818 PF12825.7 KEG05279.1 - 3.2 6.7 6.9 8.7 5.2 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) KfrA_N PF11740.8 KEG05279.1 - 3.3 8.4 23.7 6.2 7.5 6.3 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term GrpE PF01025.19 KEG05279.1 - 3.8 7.1 13.2 0.77 9.4 4.9 2.1 1 1 1 2 2 2 0 GrpE NYD-SP28_assoc PF14775.6 KEG05279.1 - 4.7 7.4 7.2 1.2 9.3 1.5 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF2730 PF10805.8 KEG05279.1 - 6 7.0 8.1 2.8 8.1 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ZapB PF06005.12 KEG05279.1 - 8.1 7.0 23.2 4.8 7.7 14.2 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Mucin PF01456.17 KEG05280.1 - 0.00013 21.9 18.1 0.00013 21.9 18.1 2.5 1 1 0 2 2 2 1 Mucin-like glycoprotein AFOR_C PF01314.18 KEG05281.1 - 0.036 13.1 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 EphA2_TM PF14575.6 KEG05282.1 - 0.027 15.3 0.0 0.039 14.8 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MAPEG PF01124.18 KEG05282.1 - 0.028 14.3 0.0 0.16 11.8 0.0 2.1 2 1 0 2 2 2 0 MAPEG family FeoB_associated PF12669.7 KEG05282.1 - 0.26 11.7 0.3 0.41 11.1 0.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CaM_bdg_C0 PF10562.9 KEG05287.1 - 0.00061 19.8 1.0 1.1 9.3 0.0 3.3 3 0 0 3 3 3 2 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ycf9 PF01737.17 KEG05287.1 - 0.18 11.7 1.9 51 3.8 0.0 3.6 4 0 0 4 4 4 0 YCF9 Cortex-I_coil PF09304.10 KEG05290.1 - 1.6e-06 28.3 6.2 2.1e-06 27.9 6.2 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil DUF1664 PF07889.12 KEG05290.1 - 0.0041 17.2 0.5 0.0058 16.7 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KEG05290.1 - 0.027 13.9 2.7 0.034 13.6 2.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5446 PF17522.2 KEG05290.1 - 0.047 13.9 1.9 0.047 13.9 1.9 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5446) HMMR_C PF15908.5 KEG05290.1 - 0.069 13.4 1.3 6.5 7.0 0.1 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal HIP1_clath_bdg PF16515.5 KEG05290.1 - 0.073 13.7 5.3 0.32 11.6 0.6 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Noelin-1 PF12308.8 KEG05290.1 - 0.095 12.7 0.2 0.2 11.7 0.2 1.5 1 1 0 1 1 1 0 Neurogenesis glycoprotein TPR_MLP1_2 PF07926.12 KEG05290.1 - 0.21 11.6 6.5 0.067 13.3 1.3 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein M PF02370.16 KEG05290.1 - 1.8 9.4 9.7 42 5.2 0.3 3.9 3 1 1 4 4 4 0 M protein repeat Peripla_BP_6 PF13458.6 KEG05292.1 - 0.0022 17.7 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF2379 PF09543.10 KEG05296.1 - 2.9 8.1 12.9 5.9 7.1 2.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2379) Atg8 PF02991.16 KEG05297.1 - 5.5e-12 45.8 0.0 6.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEG05297.1 - 0.024 15.1 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 SpoIIE PF07228.12 KEG05297.1 - 0.082 12.8 0.0 0.097 12.6 0.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) HTH_30 PF13556.6 KEG05298.1 - 0.063 13.1 0.1 0.17 11.7 0.1 1.8 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-C3HC4_3 PF13920.6 KEG05299.1 - 1.5e-11 44.0 15.5 2.5e-11 43.2 15.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG05299.1 - 8.5e-06 25.5 14.4 1.5e-05 24.7 14.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEG05299.1 - 0.0044 17.0 15.7 0.0095 15.9 15.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TFIIA PF03153.13 KEG05299.1 - 2.1 8.3 6.9 2.3 8.1 6.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RBB1NT PF08169.11 KEG05301.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain UME PF08064.13 KEG05302.1 - 0.018 15.0 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 UME (NUC010) domain SLC12 PF03522.15 KEG05307.1 - 4.1 6.3 14.3 5.8 5.8 14.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Borrelia_P83 PF05262.11 KEG05307.1 - 4.8 5.6 45.9 5.9 5.3 45.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Mucin PF01456.17 KEG05310.1 - 0.23 11.4 21.0 6.6 6.7 20.7 2.3 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF4643 PF15485.6 KEG05310.1 - 0.91 9.3 5.2 1.2 8.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4643) DUF5089 PF17002.5 KEG05311.1 - 0.00028 20.8 0.3 0.0017 18.2 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) DUF1772 PF08592.11 KEG05312.1 - 0.43 10.9 5.4 1.1 9.5 5.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MARVEL PF01284.23 KEG05312.1 - 2.9 7.9 13.9 8.6 6.4 13.8 1.9 1 1 0 1 1 1 0 Membrane-associating domain AAA PF00004.29 KEG05314.1 - 1.4e-05 25.5 0.0 0.015 15.7 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG05314.1 - 0.0027 18.1 6.2 0.0039 17.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEG05314.1 - 0.0038 17.5 1.2 0.026 14.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KEG05314.1 - 0.015 15.3 0.2 0.063 13.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEG05314.1 - 0.018 15.6 0.0 0.053 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEG05314.1 - 0.021 15.3 0.0 2.8 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KEG05314.1 - 0.051 13.3 0.1 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEG05314.1 - 0.074 13.4 1.0 0.17 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEG05314.1 - 0.11 12.7 0.7 0.31 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEG05314.1 - 0.12 12.6 3.1 0.22 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KEG05314.1 - 0.12 12.2 1.2 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 KEG05314.1 - 0.23 11.0 2.9 0.42 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain CBM_14 PF01607.24 KEG05315.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Galactosyl_T PF01762.21 KEG05317.1 - 0.06 13.2 0.1 0.32 10.8 0.0 2.2 2 1 1 3 3 3 0 Galactosyltransferase Rhomboid PF01694.22 KEG05319.1 - 0.001 19.1 0.7 0.0019 18.2 0.7 1.5 1 1 0 1 1 1 1 Rhomboid family DUF5559 PF17714.1 KEG05319.1 - 0.14 12.0 0.4 0.22 11.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) RHSP PF07999.11 KEG05320.1 - 1.7e-41 142.5 0.3 2.1e-41 142.2 0.3 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein DUF2113 PF09886.9 KEG05320.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) RBB1NT PF08169.11 KEG05322.1 - 0.17 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain CENP-T_C PF15511.6 KEG05324.1 - 3.9e-05 23.7 0.0 5.8e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KEG05324.1 - 0.013 15.8 0.2 0.04 14.2 0.0 1.8 1 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KEG05324.1 - 0.017 15.2 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 KEG05324.1 - 0.027 14.6 0.1 0.045 13.9 0.1 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Histone PF00125.24 KEG05324.1 - 0.03 14.7 0.8 0.08 13.3 0.8 1.7 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AbiEi_4 PF13338.6 KEG05324.1 - 0.031 14.4 1.6 0.93 9.7 0.8 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Bromo_TP PF07524.13 KEG05324.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Peptidase_M8 PF01457.16 KEG05325.1 - 2.7e-80 270.6 0.1 2.9e-80 270.5 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Mucin PF01456.17 KEG05326.1 - 4.4e-05 23.5 22.3 4.4e-05 23.5 22.3 2.4 2 1 0 2 2 2 2 Mucin-like glycoprotein Ntox1 PF15500.6 KEG05326.1 - 0.064 13.6 2.2 0.92 9.9 0.1 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 EphA2_TM PF14575.6 KEG05327.1 - 0.0068 17.3 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TrbL PF04610.14 KEG05327.1 - 0.08 12.7 0.7 0.12 12.1 0.7 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF4690 PF15756.5 KEG05327.1 - 0.18 12.5 0.1 0.18 12.5 0.1 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage VSP PF03302.13 KEG05327.1 - 0.22 10.3 4.6 0.51 9.1 4.8 1.5 1 1 1 2 2 2 0 Giardia variant-specific surface protein CYYR1 PF10873.8 KEG05327.1 - 1.8 9.0 4.3 4.7 7.6 4.3 1.6 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 HD-ZIP_N PF04618.12 KEG05328.1 - 0.066 13.7 0.7 0.17 12.4 0.2 1.8 2 0 0 2 2 2 0 HD-ZIP protein N terminus RNA_pol_Rpb2_5 PF04567.17 KEG05334.1 - 0.24 12.0 2.6 20 5.9 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 OGFr_III PF04680.13 KEG05339.1 - 0.00046 20.6 0.0 2 9.2 0.0 2.4 2 0 0 2 2 2 2 Opioid growth factor receptor repeat DUF922 PF06037.11 KEG05339.1 - 0.032 14.0 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) ADPRTs_Tse2 PF18648.1 KEG05340.1 - 0.094 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins NTF2 PF02136.20 KEG05341.1 - 1.5e-27 96.6 0.0 1.7e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 KEG05341.1 - 0.0029 18.2 0.0 0.0038 17.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KEG05341.1 - 0.058 13.8 0.0 0.073 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 KEG05341.1 - 0.092 13.4 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding zf-Di19 PF05605.12 KEG05342.1 - 0.011 16.0 0.4 0.024 14.9 0.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TctC PF03401.14 KEG05343.1 - 0.083 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor YrzO PF14142.6 KEG05345.1 - 0.0043 16.9 0.2 0.0073 16.2 0.2 1.3 1 0 0 1 1 1 1 YrzO-like protein TPR_MLP1_2 PF07926.12 KEG05346.1 - 0.046 13.8 29.1 0.17 11.9 11.1 4.1 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein PCRF PF03462.18 KEG05346.1 - 0.072 12.9 13.9 0.08 12.8 0.3 2.5 3 0 0 3 3 3 0 PCRF domain PKcGMP_CC PF16808.5 KEG05346.1 - 0.087 12.7 7.0 0.25 11.2 2.2 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2203 PF09969.9 KEG05346.1 - 0.21 12.3 13.7 5.3 7.8 2.7 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.22 KEG05346.1 - 0.3 11.3 17.0 1.7 8.9 5.5 3.3 3 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.13 KEG05346.1 - 0.39 10.8 21.4 0.18 11.9 2.8 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 KEG05346.1 - 0.4 10.7 9.6 1.7 8.7 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SOAR PF16533.5 KEG05346.1 - 0.4 10.7 13.1 0.045 13.7 1.5 3.2 3 1 0 3 3 3 0 STIM1 Orai1-activating region Exonuc_VII_L PF02601.15 KEG05346.1 - 1.1 8.7 21.0 0.35 10.4 6.8 2.1 1 1 0 2 2 2 0 Exonuclease VII, large subunit HOOK PF05622.12 KEG05346.1 - 1.4 7.0 22.3 0.17 10.0 7.0 2.7 2 1 0 2 2 2 0 HOOK protein DUF928 PF06051.12 KEG05346.1 - 1.6 8.5 7.4 7.9 6.3 4.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Cep57_CLD_2 PF14197.6 KEG05346.1 - 2.4 8.3 27.3 0.12 12.5 0.9 4.9 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 KEG05346.1 - 3.4 7.5 23.6 0.32 10.8 0.8 4.1 2 1 2 4 4 4 0 Septum formation initiator YlqD PF11068.8 KEG05346.1 - 4 7.8 17.5 4.8 7.6 4.0 3.3 3 1 0 3 3 3 0 YlqD protein MobC PF05713.11 KEG05346.1 - 8.8 6.9 10.0 1.9 9.0 0.1 3.6 4 0 0 4 4 4 0 Bacterial mobilisation protein (MobC) Sec3_C PF09763.9 KEG05350.1 - 3.7e-43 147.9 0.2 4.2e-43 147.7 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 BRE1 PF08647.11 KEG05350.1 - 0.015 15.4 1.1 0.048 13.7 0.0 2.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Med9 PF07544.13 KEG05350.1 - 0.024 14.7 3.3 0.42 10.7 1.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3851 PF12962.7 KEG05350.1 - 0.038 14.3 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Hemerythrin PF01814.23 KEG05350.1 - 0.16 12.6 4.3 1.3 9.7 0.0 3.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain YabA PF06156.13 KEG05350.1 - 0.17 12.6 3.4 0.26 12.0 2.3 2.0 2 1 0 2 2 2 0 Initiation control protein YabA DASH_Dam1 PF08653.10 KEG05350.1 - 0.39 10.6 4.8 0.3 10.9 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 UCH_C PF18031.1 KEG05353.1 - 0.0057 16.5 0.9 4.5 7.3 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolases UPF0158 PF03682.13 KEG05353.1 - 0.055 13.4 3.6 0.25 11.3 3.6 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) Lectin_C_term PF18022.1 KEG05353.1 - 0.064 13.7 4.0 0.4 11.2 0.7 2.4 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin C-terminal domain Flavokinase PF01687.17 KEG05354.1 - 2.9e-13 50.1 0.0 3.3e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase HU-CCDC81_bac_1 PF18174.1 KEG05354.1 - 0.033 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 PKcGMP_CC PF16808.5 KEG05355.1 - 0.021 14.7 4.1 3.1 7.7 0.1 3.1 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ACT_6 PF13740.6 KEG05355.1 - 0.09 12.8 3.3 22 5.1 0.1 3.5 3 1 1 4 4 4 0 ACT domain DUF507 PF04368.13 KEG05355.1 - 0.49 10.3 4.3 5.2 7.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF507) DUF4404 PF14357.6 KEG05355.1 - 2.1 9.0 5.5 3 8.6 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) EphA2_TM PF14575.6 KEG05356.1 - 0.0066 17.3 0.0 0.01 16.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KEG05356.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless S1FA PF04689.13 KEG05356.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4690 PF15756.5 KEG05356.1 - 0.28 11.8 7.4 0.082 13.5 3.1 2.2 1 1 1 2 2 2 0 Small Novel Rich in Cartilage PHTB1_C PF14728.6 KEG05357.1 - 0.0089 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 PTHB1 C-terminus DUF1351 PF07083.11 KEG05357.1 - 0.081 12.7 4.5 0.098 12.4 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) IFT46_B_C PF12317.8 KEG05357.1 - 0.083 12.6 0.2 0.25 11.1 0.1 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF2150 PF09920.9 KEG05357.1 - 0.46 10.4 10.5 0.022 14.8 2.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) MukF_M PF17192.4 KEG05361.1 - 0.0033 17.2 0.3 0.0033 17.2 0.3 2.4 1 1 1 2 2 2 1 MukF middle domain Not3 PF04065.15 KEG05361.1 - 0.082 12.3 7.2 0.11 11.9 6.3 1.6 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF4242 PF14026.6 KEG05361.1 - 0.59 10.4 4.7 1.9 8.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) MCPsignal PF00015.21 KEG05361.1 - 1 9.1 26.0 0.83 9.4 1.5 2.9 2 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 KEG05361.1 - 1.9 8.7 6.8 15 5.9 0.1 3.7 3 0 0 3 3 3 0 Haemolysin XhlA GARP PF16731.5 KEG05361.1 - 7.8 6.1 55.9 0.068 12.9 6.7 3.7 1 1 2 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma TMF_DNA_bd PF12329.8 KEG05361.1 - 8.6 6.4 12.1 0.49 10.4 1.9 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Myb_CC_LHEQLE PF14379.6 KEG05362.1 - 0.021 14.5 0.1 0.032 13.9 0.1 1.2 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Flagellar_rod PF05149.12 KEG05368.1 - 0.0024 17.4 2.6 0.0024 17.4 2.6 2.5 3 0 0 3 3 3 1 Paraflagellar rod protein Tropomyosin PF00261.20 KEG05368.1 - 0.0036 16.7 7.9 0.0036 16.7 7.9 3.3 1 1 2 3 3 3 2 Tropomyosin YscO PF07321.12 KEG05368.1 - 0.033 14.1 0.6 0.033 14.1 0.6 3.8 2 1 2 4 4 3 0 Type III secretion protein YscO DUF16 PF01519.16 KEG05368.1 - 0.039 14.5 4.6 1.6 9.2 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KEG05368.1 - 0.064 13.3 6.9 0.63 10.1 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KEG05368.1 - 0.12 12.7 0.3 0.12 12.7 0.3 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KEG05368.1 - 0.21 11.8 7.8 8 6.7 3.6 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DASH_Dad2 PF08654.10 KEG05368.1 - 0.22 12.0 0.2 0.22 12.0 0.2 3.1 3 1 0 3 3 2 0 DASH complex subunit Dad2 NPV_P10 PF05531.12 KEG05368.1 - 0.32 11.5 5.1 2.2 8.8 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3040 PF11239.8 KEG05368.1 - 0.38 11.1 4.7 0.98 9.7 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2730 PF10805.8 KEG05368.1 - 0.53 10.4 4.0 54 4.0 0.5 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF2730) MCU PF04678.13 KEG05368.1 - 0.6 10.2 11.9 12 6.0 11.9 2.8 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DivIVA PF05103.13 KEG05368.1 - 0.77 9.8 16.7 3 7.9 0.3 3.4 3 1 0 3 3 3 0 DivIVA protein COG5 PF10392.9 KEG05368.1 - 1.3 9.2 9.1 1.8 8.8 0.1 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 MscS_porin PF12795.7 KEG05368.1 - 1.8 8.1 40.4 0.15 11.6 6.9 2.9 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain JIP_LZII PF16471.5 KEG05368.1 - 2.6 8.3 12.0 2.3 8.4 1.7 3.9 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II OmpH PF03938.14 KEG05368.1 - 2.9 8.2 19.7 24 5.3 0.2 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 KEG05368.1 - 3.3 7.8 24.2 0.41 10.7 9.9 3.3 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.6 KEG05368.1 - 6 6.2 13.9 1.3 8.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 KEG05368.1 - 7.3 7.1 30.6 3 8.4 10.6 3.5 1 1 1 3 3 3 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 KEG05368.1 - 7.9 6.6 21.2 3.7 7.7 10.5 3.0 2 2 1 3 3 3 0 Tropomyosin like Mucin PF01456.17 KEG05369.1 - 8.8e-06 25.8 33.3 2.1e-05 24.5 24.9 3.2 2 1 0 2 2 2 2 Mucin-like glycoprotein PPR_2 PF13041.6 KEG05370.1 - 0.0033 17.6 0.2 1.9 8.7 0.1 2.4 2 0 0 2 2 2 2 PPR repeat family DUF3883 PF13020.6 KEG05371.1 - 2.2e-19 69.3 0.0 2.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF2533 PF10752.9 KEG05372.1 - 0.074 13.5 5.4 0.11 13.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) DUF4404 PF14357.6 KEG05372.1 - 3.4 8.4 14.6 0.17 12.5 1.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) Allexi_40kDa PF05549.11 KEG05372.1 - 6.8 6.1 11.6 0.66 9.4 3.8 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.11 KEG05372.1 - 9.5 4.0 7.1 13 3.6 7.1 1.3 1 0 0 1 1 1 0 Prominin LRRNT_2 PF08263.12 KEG05373.1 - 0.0038 17.5 1.0 0.013 15.8 0.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 KEG05373.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KEG05373.1 - 0.016 15.6 0.1 0.05 14.0 0.0 1.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Amastin PF07344.11 KEG05374.1 - 1.8e-08 34.4 8.2 2.9e-08 33.7 7.0 1.8 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF3522 PF12036.8 KEG05374.1 - 0.036 14.3 2.8 2.9 8.1 2.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) ASFV_J13L PF05568.11 KEG05374.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.4 3 0 0 3 3 3 0 African swine fever virus J13L protein NicO PF03824.16 KEG05374.1 - 0.73 9.1 8.8 0.06 12.7 2.6 2.1 2 0 0 2 2 2 0 High-affinity nickel-transport protein MazE_antitoxin PF04014.18 KEG05376.1 - 0.0095 15.9 0.4 1.5 8.8 0.1 2.3 1 1 1 2 2 2 2 Antidote-toxin recognition MazE, bacterial antitoxin ATP-synt_ab_N PF02874.23 KEG05376.1 - 0.15 12.6 0.0 30 5.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain K_channel_TID PF07941.11 KEG05377.1 - 0.25 11.8 4.0 0.85 10.1 4.0 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RBB1NT PF08169.11 KEG05378.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Isochorismatase PF00857.20 KEG05379.1 - 8.2e-15 55.4 0.1 1e-14 55.1 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Phage_tail_APC PF16778.5 KEG05380.1 - 0.015 15.2 0.2 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein AGOG PF09171.10 KEG05380.1 - 0.026 13.8 0.6 0.16 11.3 0.3 1.9 2 0 0 2 2 2 0 N-glycosylase/DNA lyase Lys-AminoMut_A PF09043.11 KEG05380.1 - 0.074 11.5 1.4 0.11 10.9 1.4 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Plasmodium_HRP PF05403.11 KEG05381.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) HJURP_C PF12347.8 KEG05381.1 - 0.75 9.9 6.5 76 3.5 0.1 4.1 3 1 1 4 4 4 0 Holliday junction regulator protein family C-terminal repeat SOSSC PF15925.5 KEG05381.1 - 1.8 9.9 4.1 87 4.5 4.2 2.4 1 1 0 1 1 1 0 SOSS complex subunit C CPT_N PF16484.5 KEG05382.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus RVT_1 PF00078.27 KEG05387.1 - 3e-06 26.9 0.0 3.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GARP PF16731.5 KEG05389.1 - 0.023 14.4 50.3 0.1 12.3 33.4 2.5 1 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF5082 PF16888.5 KEG05389.1 - 0.098 12.9 16.0 0.083 13.2 6.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Sec8_exocyst PF04048.14 KEG05389.1 - 0.39 10.6 6.3 0.2 11.5 1.3 2.7 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Sec34 PF04136.15 KEG05389.1 - 0.71 9.7 4.9 0.8 9.6 1.9 2.2 2 0 0 2 2 2 0 Sec34-like family COG6 PF06419.11 KEG05389.1 - 1 7.5 11.3 2.6 6.1 1.8 2.1 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 CENP-F_leu_zip PF10473.9 KEG05389.1 - 1.8 8.6 13.2 1.3 9.0 5.7 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 KEG05389.1 - 2.7 7.7 47.6 0.074 12.8 6.6 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF745) PIEZO PF15917.5 KEG05389.1 - 3.2 7.2 8.6 1.7 8.1 3.2 2.3 2 0 0 2 2 2 0 Piezo Lebercilin PF15619.6 KEG05389.1 - 3.3 7.3 17.9 0.11 12.2 6.5 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KEG05389.1 - 5.3 7.2 10.8 20 5.4 6.3 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1644 PF07800.12 KEG05390.1 - 0.00074 19.6 3.6 0.00089 19.4 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) MR_MLE_C PF13378.6 KEG05390.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Enolase C-terminal domain-like KRE1 PF17056.5 KEG05393.1 - 0.057 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 SepF PF04472.12 KEG05394.1 - 0.068 13.5 0.1 0.26 11.6 0.1 2.0 1 0 0 1 1 1 0 Cell division protein SepF Shisa PF13908.6 KEG05394.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.6 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator GARP PF16731.5 KEG05394.1 - 0.94 9.1 48.9 1.5 8.4 26.2 2.5 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma IQ PF00612.27 KEG05395.1 - 0.00025 20.5 0.9 0.0005 19.6 0.3 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif ELO PF01151.18 KEG05398.1 - 2.7e-59 200.7 10.0 3.1e-59 200.5 10.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mn_catalase PF05067.12 KEG05400.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase EF-hand_7 PF13499.6 KEG05405.1 - 0.045 14.2 0.1 0.077 13.5 0.1 1.4 1 1 0 1 1 1 0 EF-hand domain pair Lys-AminoMut_A PF09043.11 KEG05405.1 - 0.22 9.9 0.0 0.26 9.7 0.0 1.0 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit CCB2_CCB4 PF11152.8 KEG05406.1 - 0.00072 18.9 1.2 0.00085 18.7 1.2 1.2 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 BshC PF10079.9 KEG05406.1 - 0.084 11.6 1.3 0.1 11.3 0.9 1.4 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC Ribosomal_L22 PF00237.19 KEG05406.1 - 0.19 12.0 2.8 0.2 11.9 1.4 1.7 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e RRF PF01765.19 KEG05406.1 - 0.21 11.5 8.8 0.48 10.4 3.6 2.2 2 0 0 2 2 2 0 Ribosome recycling factor Mucin PF01456.17 KEG05406.1 - 0.52 10.3 17.0 2.1 8.3 17.0 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein OAF PF14941.6 KEG05406.1 - 0.75 9.2 3.4 0.36 10.2 1.3 1.5 2 0 0 2 2 2 0 Transcriptional regulator, Out at first Mitofilin PF09731.9 KEG05406.1 - 2.8 6.7 20.5 1.7 7.4 4.4 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein SKA1 PF07160.12 KEG05406.1 - 7.3 6.4 9.9 1.3 8.8 2.0 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CDC45 PF02724.14 KEG05407.1 - 4.5 5.4 16.4 5.7 5.1 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 KEG05407.1 - 9.5 6.3 20.3 11 6.0 19.8 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-MYND PF01753.18 KEG05408.1 - 4.9e-06 26.5 10.5 4.9e-06 26.5 10.5 2.6 2 2 0 2 2 2 1 MYND finger TPR_16 PF13432.6 KEG05408.1 - 7.1e-05 23.4 3.6 0.0036 17.9 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG05408.1 - 0.35 11.1 3.0 19 5.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Borrelia_P83 PF05262.11 KEG05409.1 - 0.076 11.5 26.7 0.086 11.3 26.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.11 KEG05409.1 - 0.67 10.0 31.8 0.91 9.5 31.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UPF0242 PF06785.11 KEG05409.1 - 0.76 9.8 19.0 1.1 9.4 19.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mucin PF01456.17 KEG05409.1 - 1.1 9.2 7.1 2.9 7.9 6.1 2.2 1 1 0 1 1 1 0 Mucin-like glycoprotein MMR1 PF08505.10 KEG05409.1 - 2 8.7 12.9 2.6 8.3 12.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GAGA_bind PF06217.12 KEG05409.1 - 2.5 8.3 16.0 3.1 8.0 16.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.7 KEG05409.1 - 3.9 5.5 14.2 4.3 5.4 14.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 KEG05409.1 - 6.2 3.8 10.6 6.9 3.6 10.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 KEG05409.1 - 9.3 5.1 14.8 12 4.8 14.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Mucin PF01456.17 KEG05414.1 - 2.7e-08 33.9 3.6 2.7e-08 33.9 3.6 2.7 2 1 0 2 2 2 1 Mucin-like glycoprotein DUF4081 PF13312.6 KEG05414.1 - 0.072 13.3 1.2 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) Csm2_III-A PF03750.13 KEG05415.1 - 0.035 14.9 2.1 0.088 13.7 0.4 2.3 2 0 0 2 2 2 0 Csm2 Type III-A Acetyltransf_11 PF13720.6 KEG05415.1 - 0.43 11.1 2.6 11 6.5 0.2 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_14 PF13428.6 KEG05415.1 - 3.5 8.7 6.5 17 6.6 0.3 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat ThiD2 PF17792.1 KEG05415.1 - 7.8 7.0 8.2 1.3 9.5 1.8 2.6 2 2 0 2 2 2 0 ThiD2 family Brix PF04427.18 KEG05416.1 - 5.3e-16 59.3 0.0 6.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain Na_trans_cytopl PF11933.8 KEG05418.1 - 0.037 13.8 0.6 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 Cytoplasmic domain of voltage-gated Na+ ion channel CYYR1 PF10873.8 KEG05420.1 - 0.0044 17.5 0.1 0.0072 16.8 0.1 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 KEG05420.1 - 0.0055 17.6 0.0 0.0078 17.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KEG05420.1 - 0.01 16.1 0.7 0.017 15.4 0.3 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FAM101 PF15068.6 KEG05420.1 - 0.015 15.3 1.6 0.023 14.7 1.6 1.2 1 0 0 1 1 1 0 FAM101 family Amnionless PF14828.6 KEG05420.1 - 0.036 12.9 0.1 0.061 12.2 0.1 1.3 1 1 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 KEG05420.1 - 0.056 13.0 0.9 0.069 12.7 0.0 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF2207 PF09972.9 KEG05420.1 - 0.11 11.2 0.0 2 7.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2062 PF09835.9 KEG05420.1 - 0.15 11.9 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4690 PF15756.5 KEG05420.1 - 0.21 12.2 0.3 0.21 12.2 0.3 2.6 2 1 1 3 3 3 0 Small Novel Rich in Cartilage VSP PF03302.13 KEG05420.1 - 0.26 10.1 0.2 0.37 9.6 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF202 PF02656.15 KEG05420.1 - 0.57 10.7 2.6 1.3 9.5 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) FeoB_associated PF12669.7 KEG05420.1 - 6 7.3 5.2 17 5.9 5.2 1.7 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Mucin PF01456.17 KEG05421.1 - 3e-07 30.5 48.5 0.0074 16.3 17.1 3.1 1 1 1 2 2 2 2 Mucin-like glycoprotein tRNA-synt_1c_C PF03950.18 KEG05422.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain NTP_transf_3 PF12804.7 KEG05423.1 - 0.027 14.8 0.1 0.027 14.8 0.1 1.9 2 1 0 2 2 2 0 MobA-like NTP transferase domain STAT6_C PF14596.6 KEG05425.1 - 0.0017 18.4 0.0 0.0018 18.3 0.0 1.0 1 0 0 1 1 1 1 STAT6 C-terminal Integrase_1 PF12835.7 KEG05426.1 - 0.15 12.2 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Integrase Sec8_exocyst PF04048.14 KEG05428.1 - 0.32 10.9 4.5 1.3 8.9 0.7 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain PIN_8 PF18476.1 KEG05428.1 - 5.2 6.9 8.3 1.2 8.9 4.4 1.8 1 1 1 2 2 2 0 PIN like domain FliJ PF02050.16 KEG05429.1 - 0.00073 19.8 5.0 0.074 13.3 2.7 2.3 2 0 0 2 2 2 2 Flagellar FliJ protein Mucin PF01456.17 KEG05429.1 - 0.003 17.6 4.6 0.0061 16.6 4.7 1.6 1 1 0 1 1 1 1 Mucin-like glycoprotein Tropomyosin PF00261.20 KEG05429.1 - 0.023 14.1 7.3 0.055 12.8 1.3 2.1 2 0 0 2 2 2 0 Tropomyosin MscS_porin PF12795.7 KEG05429.1 - 0.031 13.8 7.1 0.75 9.3 3.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pox_vIL-18BP PF05566.12 KEG05429.1 - 0.15 12.3 0.0 16 5.8 0.0 2.4 1 1 1 2 2 2 0 Orthopoxvirus interleukin 18 binding protein EFhand_Ca_insen PF08726.10 KEG05429.1 - 0.15 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Synaptobrevin PF00957.21 KEG05429.1 - 0.24 11.2 3.3 3.4 7.5 0.3 2.5 2 0 0 2 2 2 0 Synaptobrevin DUF2277 PF10041.9 KEG05429.1 - 0.4 11.0 5.0 0.68 10.3 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Rx_N PF18052.1 KEG05429.1 - 0.41 10.9 4.1 0.55 10.6 0.4 2.6 2 1 1 3 3 3 0 Rx N-terminal domain DUF3080 PF11279.8 KEG05429.1 - 1 8.5 6.2 0.35 10.0 3.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) DUF3584 PF12128.8 KEG05429.1 - 1.7 6.1 10.8 3.2 5.1 10.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 KEG05429.1 - 2.2 8.3 9.8 3.5 7.7 0.2 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 KEG05429.1 - 3 8.2 10.9 6.1 7.2 0.7 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SNARE PF05739.19 KEG05429.1 - 5.5 7.1 7.4 21 5.2 0.2 3.0 3 0 0 3 3 3 0 SNARE domain DUF3713 PF12506.8 KEG05429.1 - 6.1 7.2 7.8 0.89 9.9 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) COG2 PF06148.11 KEG05429.1 - 6.2 6.9 8.2 4.5 7.4 1.6 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3439 PF11921.8 KEG05431.1 - 0.0089 16.0 3.3 0.017 15.1 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 KEG05431.1 - 0.02 13.0 4.6 0.023 12.8 4.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spc7 PF08317.11 KEG05432.1 - 0.0057 15.6 7.7 0.0057 15.6 7.7 2.6 1 1 0 2 2 2 1 Spc7 kinetochore protein Dynactin_p22 PF07426.11 KEG05432.1 - 0.23 11.3 5.9 4.9 7.0 0.8 2.4 1 1 1 2 2 2 0 Dynactin subunit p22 DUF1664 PF07889.12 KEG05432.1 - 1.5 8.8 11.4 0.18 11.9 3.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 KEG05432.1 - 1.7 8.5 8.2 0.22 11.4 0.4 3.0 2 1 0 3 3 3 0 Sec34-like family DUF4559 PF15112.6 KEG05432.1 - 7.1 6.2 8.5 0.98 9.0 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) LRR_9 PF14580.6 KEG05434.1 - 1e-08 34.9 0.2 8.7e-05 22.1 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KEG05434.1 - 1e-07 32.1 12.3 4.3e-05 23.8 3.2 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG05434.1 - 0.02 14.6 5.2 0.041 13.6 3.7 2.3 1 1 1 2 2 2 0 Leucine rich repeat Rotamase_2 PF13145.6 KEG05439.1 - 0.088 13.6 2.6 0.17 12.7 2.6 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF728 PF05304.12 KEG05439.1 - 0.094 12.6 1.6 0.19 11.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Cas6b_C PF17262.2 KEG05439.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Cas6b C-terminal domain Zip PF02535.22 KEG05440.1 - 0.0042 16.3 5.8 0.0064 15.8 5.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter LysM PF01476.20 KEG05441.1 - 1e-06 28.7 0.0 0.0087 16.1 0.0 2.9 3 0 0 3 3 3 2 LysM domain DUF4677 PF15726.5 KEG05443.1 - 0.047 13.8 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Rieske PF00355.26 KEG05444.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain RVT_1 PF00078.27 KEG05446.1 - 4.3e-35 121.2 0.0 5.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RanBP PF00641.18 KEG05449.1 - 0.027 13.8 15.8 0.063 12.6 8.9 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Cytochrom_CIII PF02085.16 KEG05449.1 - 0.031 14.6 0.3 0.031 14.6 0.3 2.0 2 0 0 2 2 2 0 Class III cytochrome C family Cytochrom_c3_2 PF14537.6 KEG05449.1 - 0.17 12.4 6.2 4.2 7.9 0.7 2.5 2 0 0 2 2 2 0 Cytochrome c3 DZR PF12773.7 KEG05449.1 - 4.8 7.3 15.8 1.4e+02 2.6 6.2 2.6 2 1 1 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KEG05449.1 - 5.9 6.5 11.0 1.3 8.6 6.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain SGS PF05002.15 KEG05450.1 - 8.1e-30 102.8 0.1 1.3e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KEG05450.1 - 0.00013 22.9 0.0 0.00019 22.4 0.0 1.2 1 0 0 1 1 1 1 CS domain CLN3 PF02487.17 KEG05451.1 - 7e-16 58.3 11.8 9e-16 57.9 11.8 1.1 1 0 0 1 1 1 1 CLN3 protein FAM165 PF14981.6 KEG05452.1 - 0.00053 19.7 1.5 0.00062 19.5 0.9 1.4 1 1 0 1 1 1 1 FAM165 family TTL PF03133.15 KEG05453.1 - 2.6e-05 23.5 0.1 5.1e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family WD40 PF00400.32 KEG05455.1 - 0.003 18.4 0.1 0.0092 16.8 0.1 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF2804 PF10974.8 KEG05456.1 - 4.4e-17 62.6 0.2 5.3e-17 62.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) APG6_N PF17675.1 KEG05457.1 - 0.0007 20.1 17.0 0.00099 19.6 17.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KEG05457.1 - 0.0067 16.6 13.0 0.013 15.7 13.0 1.5 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 KEG05457.1 - 0.0072 16.7 13.9 0.011 16.2 13.9 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Lectin_N PF03954.14 KEG05457.1 - 0.012 15.4 2.4 0.012 15.4 2.4 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DivIC PF04977.15 KEG05457.1 - 0.023 14.4 5.2 0.023 14.4 5.2 3.0 1 1 2 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 KEG05457.1 - 0.027 14.6 13.7 0.033 14.3 13.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KEG05457.1 - 0.036 14.1 16.3 0.046 13.8 16.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KEG05457.1 - 0.096 12.0 13.0 0.13 11.5 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 KEG05457.1 - 0.15 12.3 16.4 0.52 10.6 16.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) bZIP_1 PF00170.21 KEG05457.1 - 0.16 12.1 11.7 0.4 10.8 7.3 2.6 1 1 1 2 2 2 0 bZIP transcription factor YabA PF06156.13 KEG05457.1 - 0.2 12.3 9.6 0.75 10.5 9.6 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Fib_alpha PF08702.10 KEG05457.1 - 0.22 11.7 5.3 0.26 11.5 5.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 KEG05457.1 - 0.32 11.2 15.0 0.45 10.7 15.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 BST2 PF16716.5 KEG05457.1 - 0.36 11.4 15.1 0.48 11.0 14.4 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 AAA_13 PF13166.6 KEG05457.1 - 0.4 9.3 8.6 0.47 9.0 8.6 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.19 KEG05457.1 - 0.53 10.0 21.9 0.7 9.7 21.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 KEG05457.1 - 0.64 10.3 12.3 0.91 9.8 12.3 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.19 KEG05457.1 - 0.71 7.7 8.9 0.73 7.7 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 KEG05457.1 - 0.74 10.3 23.3 48 4.5 23.3 2.5 1 1 0 1 1 1 0 Cell division protein ZapB OmpH PF03938.14 KEG05457.1 - 0.74 10.1 16.6 1.1 9.6 16.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.18 KEG05457.1 - 0.81 10.0 11.3 3.1 8.1 5.9 3.2 2 1 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 KEG05457.1 - 0.96 9.7 12.0 0.58 10.4 6.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 KEG05457.1 - 1.1 9.5 10.9 0.54 10.4 1.7 2.3 1 1 1 2 2 2 0 Swi5 TMPIT PF07851.13 KEG05457.1 - 1.1 8.4 7.8 1.2 8.3 7.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.11 KEG05457.1 - 1.3 6.9 6.6 1.4 6.8 6.6 1.0 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KEG05457.1 - 1.4 7.7 14.6 1.8 7.3 14.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KEG05457.1 - 1.7 7.9 12.9 4.4 6.6 12.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 KEG05457.1 - 2.8 8.3 13.0 1.7 9.0 6.9 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain SseC PF04888.12 KEG05457.1 - 3.6 7.1 9.3 0.55 9.8 4.9 1.6 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Cnn_1N PF07989.11 KEG05457.1 - 4.3 7.6 14.2 0.75 10.0 6.8 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CENP-Q PF13094.6 KEG05457.1 - 6.1 7.0 17.3 37 4.5 17.3 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.12 KEG05457.1 - 7.7 4.9 11.1 8.8 4.7 11.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM76 PF16046.5 KEG05457.1 - 9.1 5.5 10.9 41 3.4 10.9 1.8 1 1 0 1 1 1 0 FAM76 protein Peptidase_M8 PF01457.16 KEG05458.1 - 1.7e-74 251.5 4.0 8.8e-63 212.8 3.9 2.0 1 1 1 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG05458.1 - 0.023 14.9 0.1 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KEG05458.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Urocanase_N PF17391.2 KEG05458.1 - 0.072 12.8 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Urocanase N-terminal domain ACP_PD PF04336.12 KEG05460.1 - 0.019 15.4 0.0 0.03 14.8 0.0 1.4 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase Formyl_trans_N PF00551.19 KEG05462.1 - 0.14 11.9 0.3 0.3 10.8 0.3 1.5 1 0 0 1 1 1 0 Formyl transferase 7TM_GPCR_Srv PF10323.9 KEG05466.1 - 0.015 14.7 0.9 0.017 14.5 0.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv EphA2_TM PF14575.6 KEG05466.1 - 0.026 15.4 0.5 0.036 14.9 0.5 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GWT1 PF06423.12 KEG05466.1 - 0.028 14.6 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 GWT1 DUF4381 PF14316.6 KEG05466.1 - 0.066 13.5 0.2 0.081 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CENP-F_leu_zip PF10473.9 KEG05468.1 - 0.009 16.0 26.9 0.05 13.6 14.3 2.4 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 KEG05468.1 - 0.011 16.1 3.1 0.64 10.4 1.0 3.0 2 2 1 3 3 3 0 Lipoprotein leucine-zipper EspB_PE PF18625.1 KEG05468.1 - 0.028 14.9 1.0 0.42 11.1 0.0 2.7 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain BTAD PF03704.17 KEG05468.1 - 0.24 11.8 8.1 0.041 14.3 3.4 2.1 2 1 0 2 2 2 0 Bacterial transcriptional activator domain DUF4618 PF15397.6 KEG05468.1 - 0.66 9.4 23.5 0.051 13.0 3.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) FAM76 PF16046.5 KEG05468.1 - 1.3 8.3 19.1 0.67 9.3 15.3 2.0 1 1 1 2 2 2 0 FAM76 protein Fez1 PF06818.15 KEG05468.1 - 1.5 9.3 25.4 1.4e+02 2.8 24.6 2.2 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.11 KEG05468.1 - 2 8.6 31.2 2.7 8.2 5.3 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 KEG05468.1 - 2.9 7.7 30.0 38 4.0 18.2 3.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 KEG05468.1 - 3.3 7.0 16.3 21 4.4 16.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KEG05468.1 - 3.5 8.1 36.8 0.12 12.9 9.1 4.2 2 1 2 4 4 4 0 Cell division protein ZapB Spc24 PF08286.11 KEG05468.1 - 5.5 7.3 22.0 17 5.7 3.3 3.4 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF2508 PF10704.9 KEG05468.1 - 9.1 6.5 13.8 1.3 9.2 2.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2508) MAS20 PF02064.15 KEG05469.1 - 0.44 10.6 0.0 0.44 10.6 0.0 2.1 1 1 1 2 2 2 0 MAS20 protein import receptor PspB PF06667.12 KEG05470.1 - 0.096 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B DNA_pol_viral_C PF00336.18 KEG05471.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Spc7 PF08317.11 KEG05471.1 - 0.095 11.6 13.0 0.14 11.0 13.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-O PF09496.10 KEG05471.1 - 0.69 9.8 10.9 0.078 12.9 2.6 2.1 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component Mucin PF01456.17 KEG05471.1 - 1.1 9.3 7.6 0.52 10.3 5.1 1.7 1 1 1 2 2 2 0 Mucin-like glycoprotein Syntaxin-6_N PF09177.11 KEG05471.1 - 9.8 6.8 8.4 31 5.2 7.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal WW PF00397.26 KEG05474.1 - 1.6e-09 37.7 0.2 2.7e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 WW domain ACBP PF00887.19 KEG05475.1 - 7e-27 93.5 0.5 7.9e-27 93.3 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Alanine_zipper PF11839.8 KEG05476.1 - 0.92 9.9 53.0 0.09 13.2 11.8 4.1 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Ribosomal_L17 PF01196.19 KEG05476.1 - 2.4 9.1 5.1 0.81 10.6 1.5 2.0 2 1 0 2 2 2 0 Ribosomal protein L17 Rad21_Rec8 PF04824.16 KEG05481.1 - 6.2e-10 38.2 0.1 1.3e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein CNDH2_C PF16858.5 KEG05481.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term USP8_dimer PF08969.11 KEG05483.1 - 0.023 14.9 0.5 0.049 13.8 0.5 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain SapC PF07277.11 KEG05483.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SapC Mucin PF01456.17 KEG05484.1 - 1e-06 28.8 16.0 1e-06 28.8 16.0 4.2 1 1 4 5 5 5 2 Mucin-like glycoprotein BNIP3 PF06553.12 KEG05484.1 - 1 9.0 11.2 2.4 7.8 11.2 1.7 1 0 0 1 1 1 0 BNIP3 Peptidase_M8 PF01457.16 KEG05485.1 - 4.7e-32 111.4 9.2 3.6e-17 62.2 0.7 2.0 1 1 1 2 2 2 2 Leishmanolysin SapA PF02199.15 KEG05485.1 - 0.13 12.6 0.2 0.13 12.6 0.2 2.2 2 0 0 2 2 2 0 Saposin A-type domain zf_CCCH_4 PF18345.1 KEG05487.1 - 0.0002 21.3 12.1 0.072 13.2 3.3 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KEG05487.1 - 0.0031 17.4 3.3 0.0031 17.4 3.3 3.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG05487.1 - 0.004 16.9 4.7 0.004 16.9 4.7 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 KEG05487.1 - 0.017 15.8 5.3 0.17 12.6 0.4 2.9 3 0 0 3 3 3 0 Torus domain Peptidase_C1 PF00112.23 KEG05488.1 - 2.4e-47 161.8 0.3 3.3e-47 161.4 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease DUF3586 PF12131.8 KEG05488.1 - 1.3e-20 73.4 8.6 3e-20 72.2 8.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.15 KEG05488.1 - 0.0091 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family AftA_N PF12250.8 KEG05489.1 - 0.026 13.3 0.2 0.026 13.3 0.2 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal MAP17 PF15807.5 KEG05492.1 - 0.00026 21.2 0.1 0.00045 20.5 0.1 1.3 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 KEG05492.1 - 0.0035 17.6 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PAG PF15347.6 KEG05492.1 - 0.0053 15.8 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched PRIMA1 PF16101.5 KEG05492.1 - 0.012 15.6 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cadherin_C_2 PF16492.5 KEG05492.1 - 0.039 14.7 0.0 0.075 13.8 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Herpes_glycop PF01528.16 KEG05492.1 - 0.061 12.2 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DAP10 PF07213.11 KEG05492.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 KEG05492.1 - 0.11 13.3 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SieB PF14163.6 KEG05492.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Corona_S2 PF01601.16 KEG05492.1 - 0.18 10.3 6.7 0.27 9.7 6.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Vpu PF00558.19 KEG05492.1 - 0.2 11.4 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Vpu protein TMEM154 PF15102.6 KEG05492.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family TMIE PF16038.5 KEG05492.1 - 0.34 10.8 2.8 0.57 10.1 2.8 1.3 1 0 0 1 1 1 0 TMIE protein Mucin PF01456.17 KEG05494.1 - 0.04 13.9 4.4 0.044 13.8 0.0 3.0 3 1 0 3 3 3 0 Mucin-like glycoprotein DDE_Tnp_IS240 PF13610.6 KEG05494.1 - 0.21 11.8 2.1 0.86 9.8 0.0 2.6 3 0 0 3 3 3 0 DDE domain TPR_10 PF13374.6 KEG05494.1 - 1.3 9.0 6.6 9.5 6.2 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Pex19 PF04614.12 KEG05494.1 - 4.7 6.9 7.8 7.3 6.3 6.9 2.0 1 1 0 1 1 1 0 Pex19 protein family PRKG1_interact PF15898.5 KEG05495.1 - 0.00075 20.4 1.9 0.00075 20.4 1.9 2.7 2 1 0 3 3 3 1 cGMP-dependent protein kinase interacting domain Hemerythrin PF01814.23 KEG05495.1 - 0.04 14.5 1.4 0.04 14.5 1.4 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain KASH_CCD PF14662.6 KEG05495.1 - 0.041 13.7 5.5 2.4 7.9 7.0 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Exonuc_VII_L PF02601.15 KEG05495.1 - 0.13 11.8 9.2 0.19 11.2 9.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HALZ PF02183.18 KEG05495.1 - 0.29 11.4 5.4 1.6 9.0 0.5 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper CtIP_N PF10482.9 KEG05495.1 - 0.36 10.9 13.0 0.25 11.4 1.2 2.4 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain CENP-H PF05837.12 KEG05495.1 - 0.55 10.7 10.1 0.11 12.9 6.2 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 KEG05495.1 - 0.95 9.5 7.6 5 7.2 1.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 KEG05495.1 - 1.5 9.2 4.7 5.7 7.3 0.5 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family FUSC PF04632.12 KEG05495.1 - 2.5 6.5 10.0 3.4 6.1 10.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4201 PF13870.6 KEG05495.1 - 2.9 7.6 12.6 0.57 9.9 1.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) YabA PF06156.13 KEG05495.1 - 8.8 7.0 7.9 21 5.8 0.6 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Alanine_zipper PF11839.8 KEG05496.1 - 0.25 11.8 64.7 0.78 10.1 0.1 5.6 3 2 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF16 PF01519.16 KEG05496.1 - 0.47 11.0 3.4 1.7 9.2 3.5 1.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 KEG05496.1 - 2.1 8.4 18.0 5.2 7.1 2.7 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4995 PF16386.5 KEG05496.1 - 5.1 7.2 5.7 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF4200 PF13863.6 KEG05498.1 - 6.4e-05 23.3 17.2 6.4e-05 23.3 17.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 KEG05498.1 - 0.00013 21.9 19.1 0.00032 20.6 19.1 1.7 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KEG05498.1 - 0.0058 15.6 19.0 0.013 14.4 19.0 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein SPX PF03105.19 KEG05498.1 - 0.013 15.4 2.8 0.018 15.0 2.8 1.3 1 0 0 1 1 1 0 SPX domain Atg14 PF10186.9 KEG05498.1 - 0.054 12.6 13.1 0.13 11.3 13.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cluap1 PF10234.9 KEG05498.1 - 0.071 12.5 15.6 0.63 9.4 4.6 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 IFT57 PF10498.9 KEG05498.1 - 0.14 11.1 12.5 0.24 10.4 12.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Macoilin PF09726.9 KEG05498.1 - 0.5 8.9 15.8 0.76 8.3 15.8 1.2 1 0 0 1 1 1 0 Macoilin family ATG16 PF08614.11 KEG05498.1 - 0.52 10.5 37.8 0.34 11.1 20.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KEG05498.1 - 0.62 9.4 23.0 0.019 14.3 5.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KEG05498.1 - 0.93 9.8 4.1 2.9 8.2 3.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 KEG05498.1 - 1.3 7.6 4.8 2.2 6.8 4.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 KEG05498.1 - 4.4 7.2 16.9 0.31 10.9 5.0 3.5 1 1 3 4 4 4 0 Prefoldin subunit Tup_N PF08581.10 KEG05498.1 - 4.9 7.5 15.7 2.2 8.7 7.3 2.4 2 0 0 2 2 2 0 Tup N-terminal Mod_r PF07200.13 KEG05498.1 - 6.9 6.8 21.2 2.4 8.3 17.6 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LMBR1 PF04791.16 KEG05498.1 - 8.9 5.1 5.7 13 4.5 5.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PUB PF09409.10 KEG05499.1 - 5.9e-33 112.6 0.0 5.8e-17 61.4 0.0 2.5 2 0 0 2 2 2 2 PUB domain SHOCT PF09851.9 KEG05499.1 - 0.008 15.9 2.4 0.008 15.9 2.4 2.3 2 0 0 2 2 2 1 Short C-terminal domain ETC_C1_NDUFA5 PF04716.14 KEG05499.1 - 0.084 12.7 1.6 0.46 10.3 0.3 2.6 3 0 0 3 3 3 0 ETC complex I subunit conserved region Alanine_zipper PF11839.8 KEG05501.1 - 0.0013 19.0 9.9 0.0013 19.0 9.9 5.9 4 3 1 5 5 5 4 Alanine-zipper, major outer membrane lipoprotein Ly49 PF08391.10 KEG05501.1 - 0.19 12.1 0.1 0.47 10.8 0.1 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region RCDG1 PF15725.5 KEG05502.1 - 0.018 15.5 0.6 0.029 14.8 0.6 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein SMN PF06003.12 KEG05502.1 - 0.9 8.7 2.6 1.1 8.4 2.6 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF5521 PF17659.1 KEG05508.1 - 0.057 11.3 0.6 0.065 11.1 0.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Mucin PF01456.17 KEG05510.1 - 0.0045 17.0 1.9 0.0045 17.0 1.9 2.9 3 1 0 3 3 3 1 Mucin-like glycoprotein Pex19 PF04614.12 KEG05510.1 - 0.48 10.1 11.6 3.8 7.2 11.6 2.2 1 1 0 1 1 1 0 Pex19 protein family E1-E2_ATPase PF00122.20 KEG05511.1 - 7.8e-47 159.1 0.9 1.5e-46 158.2 0.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KEG05511.1 - 9.4e-14 50.9 0.0 2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus SUR7 PF06687.12 KEG05511.1 - 0.005 16.5 6.1 0.005 16.5 6.1 1.9 2 0 0 2 2 2 1 SUR7/PalI family DUF2628 PF10947.8 KEG05511.1 - 0.36 11.2 3.7 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DFRP_C PF16543.5 KEG05512.1 - 9.1e-12 45.3 10.4 9.1e-12 45.3 10.4 2.8 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 PTS_IIA PF02255.16 KEG05514.1 - 0.45 10.6 13.8 0.044 13.8 3.4 3.1 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit CortBP2 PF09727.9 KEG05514.1 - 0.45 10.4 12.5 1.3 8.9 12.5 1.9 1 1 0 1 1 1 0 Cortactin-binding protein-2 Miga PF10265.9 KEG05514.1 - 0.48 9.3 6.7 0.57 9.1 6.7 1.1 1 0 0 1 1 1 0 Mitoguardin GARP PF16731.5 KEG05514.1 - 0.71 9.5 32.3 0.67 9.6 10.4 2.3 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma APG17 PF04108.12 KEG05514.1 - 1 8.4 12.3 0.067 12.3 1.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 LRS4 PF10422.9 KEG05514.1 - 1.1 8.7 11.5 5 6.6 11.0 2.1 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Mucin PF01456.17 KEG05514.1 - 2.5 8.1 11.1 82 3.2 11.1 2.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Muted PF14942.6 KEG05514.1 - 4.4 7.6 10.1 2.3 8.6 4.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein MIF4G_like_2 PF09090.11 KEG05514.1 - 8.3 5.8 15.2 0.63 9.5 7.5 2.0 1 1 0 2 2 2 0 MIF4G like Peptidase_M8 PF01457.16 KEG05516.1 - 1.6e-06 27.1 0.5 2.5e-06 26.5 0.5 1.2 1 0 0 1 1 1 1 Leishmanolysin Pox_Ag35 PF03286.14 KEG05516.1 - 0.00012 21.9 5.5 0.00016 21.5 5.5 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Zip PF02535.22 KEG05516.1 - 0.065 12.4 0.5 0.081 12.1 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 KEG05516.1 - 0.11 11.2 4.8 0.14 11.0 4.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KEG05516.1 - 0.14 10.9 2.4 0.17 10.6 2.4 1.2 1 0 0 1 1 1 0 Presenilin DUF2992 PF11208.8 KEG05516.1 - 0.33 11.2 5.9 0.5 10.6 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) tRNA_bind_2 PF13725.6 KEG05516.1 - 2.3 7.8 5.8 2.9 7.5 5.8 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain RR_TM4-6 PF06459.12 KEG05516.1 - 2.6 7.8 7.5 3.3 7.5 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Smg8_Smg9 PF10220.9 KEG05516.1 - 4.5 5.5 5.8 5.3 5.2 5.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 TRAM_LAG1_CLN8 PF03798.16 KEG05518.1 - 1.2e-09 38.3 4.1 1.2e-09 38.2 4.1 1.2 1 0 0 1 1 1 1 TLC domain ATG16 PF08614.11 KEG05520.1 - 3.9e-05 24.0 28.3 0.0001 22.6 9.4 2.5 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Med9 PF07544.13 KEG05520.1 - 0.0086 16.1 2.0 0.024 14.7 2.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HAUS-augmin3 PF14932.6 KEG05520.1 - 0.013 15.0 6.4 0.013 15.0 6.4 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 KEG05520.1 - 0.12 12.5 0.3 0.22 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KEG05520.1 - 5.8 7.1 16.8 12 6.1 1.5 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 KEG05520.1 - 6.5 5.7 13.5 6.4 5.8 12.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nodulin-like PF06813.13 KEG05522.1 - 1.6e-07 31.1 7.0 1.8e-07 30.9 7.0 1.0 1 0 0 1 1 1 1 Nodulin-like Guanylate_cyc PF00211.20 KEG05528.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2121 PF09894.9 KEG05528.1 - 0.23 11.0 0.1 0.64 9.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) PEP_mutase PF13714.6 KEG05529.1 - 4.7e-70 235.8 0.7 1.9e-38 132.3 0.2 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase L27 PF02828.16 KEG05529.1 - 0.026 14.3 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 L27 domain PA PF02225.22 KEG05529.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 PA domain CLN3 PF02487.17 KEG05530.1 - 9.2e-35 120.4 0.0 1.7e-34 119.6 0.0 1.5 1 1 0 1 1 1 1 CLN3 protein TOM6p PF15184.6 KEG05530.1 - 0.036 13.8 0.3 6 6.7 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Nucleoside_tran PF01733.18 KEG05530.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.6 2 1 1 3 3 3 0 Nucleoside transporter Myosin_tail_1 PF01576.19 KEG05531.1 - 0.091 10.6 1.1 0.11 10.3 1.1 1.0 1 0 0 1 1 1 0 Myosin tail ZapB PF06005.12 KEG05531.1 - 2.8 8.5 6.9 0.99 9.9 3.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB HisKA PF00512.25 KEG05532.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain RNase_H2_suC PF08615.11 KEG05533.1 - 1.1e-15 58.0 0.0 1.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FLgD_tudor PF13861.6 KEG05533.1 - 0.057 13.7 0.4 0.077 13.3 0.4 1.2 1 0 0 1 1 1 0 FlgD Tudor-like domain GTP_cyclohydroI PF01227.22 KEG05533.1 - 0.099 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I Mucin PF01456.17 KEG05534.1 - 9.1e-11 41.9 29.4 7.3e-08 32.5 8.1 3.3 3 0 0 3 3 3 2 Mucin-like glycoprotein LXG PF04740.12 KEG05534.1 - 0.0007 19.4 1.3 0.0007 19.4 1.3 3.4 3 1 0 3 3 3 1 LXG domain of WXG superfamily TRF PF08558.10 KEG05534.1 - 0.017 14.7 0.2 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) IFP_35_N PF07334.13 KEG05534.1 - 0.037 14.1 0.8 0.12 12.5 0.8 1.9 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FH2 PF02181.23 KEG05534.1 - 0.066 12.3 19.7 0.038 13.1 1.8 3.1 3 0 0 3 3 3 0 Formin Homology 2 Domain RasGAP_C PF03836.15 KEG05534.1 - 0.13 12.5 6.7 0.56 10.4 2.4 2.5 2 0 0 2 2 2 0 RasGAP C-terminus SlyX PF04102.12 KEG05534.1 - 0.2 12.3 4.7 1 10.1 4.3 2.5 1 1 0 1 1 1 0 SlyX GIT_CC PF16559.5 KEG05534.1 - 6.5 6.7 7.8 0.37 10.7 0.6 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 KEG05534.1 - 6.7 7.2 10.9 2.4 8.6 1.3 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Rep_4 PF05797.11 KEG05534.1 - 7.3 5.6 9.5 0.4 9.8 4.3 1.5 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Rab5-bind PF09311.11 KEG05534.1 - 7.6 5.8 21.8 0.026 13.9 4.2 3.2 2 1 0 3 3 3 0 Rabaptin-like protein TMF_TATA_bd PF12325.8 KEG05534.1 - 9.4 6.5 24.3 1.9 8.7 0.7 3.9 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Mucin PF01456.17 KEG05535.1 - 1.4 8.9 13.1 0.053 13.5 1.7 2.6 1 1 0 2 2 2 0 Mucin-like glycoprotein KfrA_N PF11740.8 KEG05535.1 - 1.5 9.5 23.3 0.067 13.9 8.5 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term SNARE PF05739.19 KEG05535.1 - 1.7 8.7 4.8 9.9 6.3 0.2 3.0 2 1 1 3 3 3 0 SNARE domain CP12 PF02672.15 KEG05535.1 - 4 8.3 22.4 0.79 10.5 5.1 2.4 2 0 0 2 2 2 0 CP12 domain BRE1 PF08647.11 KEG05535.1 - 8.6 6.5 25.0 5.3 7.2 5.9 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Aminotran_1_2 PF00155.21 KEG05536.1 - 8.5e-37 127.2 0.0 9.8e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEG05536.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEG05536.1 - 0.001 17.7 0.0 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 KEG05538.1 - 1.3e-14 54.3 16.4 0.00016 22.4 0.5 5.7 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG05538.1 - 0.0013 19.0 0.0 1.2 9.4 0.0 3.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KEG05538.1 - 0.021 14.8 0.1 14 5.8 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cnn_1N PF07989.11 KEG05539.1 - 0.027 14.6 1.1 0.027 14.6 1.1 7.4 3 1 4 7 7 7 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 KEG05539.1 - 9.1 6.5 99.2 0.89 9.8 19.7 5.1 1 1 4 5 5 5 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 KEG05540.1 - 1.2e-58 198.6 0.0 1.5e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG05540.1 - 6.5e-25 87.9 0.1 2.5e-24 86.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG05540.1 - 0.00062 19.2 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEG05540.1 - 0.0009 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG05540.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KEG05540.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Reovirus_cap PF00979.17 KEG05541.1 - 0.076 12.2 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Lsr2 PF11774.8 KEG05543.1 - 0.083 13.0 0.6 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 Lsr2 Peripla_BP_6 PF13458.6 KEG05544.1 - 0.015 15.0 0.2 0.037 13.7 0.2 1.5 1 1 0 1 1 1 0 Periplasmic binding protein Alanine_zipper PF11839.8 KEG05545.1 - 0.018 15.4 78.5 0.05 14.0 7.5 5.7 4 2 1 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein DUF948 PF06103.11 KEG05545.1 - 2.7 8.3 12.6 0.14 12.4 0.5 3.6 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TPMT PF05724.11 KEG05546.1 - 9e-14 51.7 0.1 9e-14 51.7 0.1 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KEG05546.1 - 0.0036 18.0 0.0 0.0068 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ret2_MD PF18528.1 KEG05550.1 - 0.093 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain RHSP PF07999.11 KEG05551.1 - 1.3e-34 119.8 0.0 1.5e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein ProSAAS PF07259.12 KEG05552.1 - 0.31 11.0 4.3 12 5.8 0.1 2.0 1 1 1 2 2 2 0 ProSAAS precursor Propeptide_C1 PF08127.13 KEG05555.1 - 0.066 13.1 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Peptidase family C1 propeptide NolV PF06635.12 KEG05559.1 - 0.011 15.2 1.7 0.011 15.2 1.7 1.5 1 1 0 1 1 1 0 Nodulation protein NolV DUF4686 PF15742.5 KEG05559.1 - 0.18 10.9 18.2 0.016 14.4 11.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) P4Ha_N PF08336.11 KEG05559.1 - 1.5 8.9 7.8 1.6 8.7 1.2 3.5 1 1 3 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ATP11 PF06644.11 KEG05561.1 - 6.5e-21 75.3 0.5 9.1e-21 74.8 0.5 1.2 1 0 0 1 1 1 1 ATP11 protein Tropomyosin PF00261.20 KEG05564.1 - 0.004 16.6 9.0 0.0051 16.2 9.0 1.1 1 0 0 1 1 1 1 Tropomyosin LETM1 PF07766.13 KEG05564.1 - 0.0084 15.5 2.2 0.011 15.1 1.8 1.3 1 1 0 1 1 1 1 LETM1-like protein IKBKB_SDD PF18397.1 KEG05564.1 - 0.026 13.8 0.5 0.043 13.1 0.5 1.3 1 1 0 1 1 1 0 IQBAL scaffold dimerization domain Aida_N PF08910.10 KEG05564.1 - 0.11 12.9 2.6 0.26 11.7 1.5 2.0 1 1 1 2 2 2 0 Aida N-terminus DUF1515 PF07439.11 KEG05564.1 - 0.17 11.9 2.0 0.3 11.1 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF3391 PF11871.8 KEG05564.1 - 1.4 9.4 5.2 4.9 7.7 5.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) BST2 PF16716.5 KEG05564.1 - 1.5 9.4 8.3 0.6 10.7 4.1 2.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Mucin PF01456.17 KEG05564.1 - 1.7 8.7 11.5 3.5 7.6 11.5 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF948 PF06103.11 KEG05564.1 - 1.9 8.8 14.5 4.4 7.6 9.3 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 KEG05564.1 - 2.6 7.2 5.0 2.4 7.3 4.1 1.4 1 1 0 1 1 1 0 TMPIT-like protein Alanine_zipper PF11839.8 KEG05564.1 - 5.4 7.5 13.7 5.3 7.5 7.1 2.7 1 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein 4PPT_N PF17837.1 KEG05567.1 - 0.0082 16.2 1.1 0.02 15.0 1.1 1.7 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 KEG05567.1 - 0.056 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily zf-CCCH PF00642.24 KEG05571.1 - 5.9e-07 29.2 1.9 5.9e-07 29.2 1.9 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG05571.1 - 0.00018 21.4 0.6 0.00045 20.2 0.6 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEG05571.1 - 0.04 13.7 1.4 0.11 12.4 1.4 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KEG05571.1 - 0.1 13.1 0.9 0.31 11.6 0.9 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RCR PF12273.8 KEG05571.1 - 2.8 8.6 7.2 35 5.1 7.2 2.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Phage_holin_7_1 PF16081.5 KEG05572.1 - 0.078 13.2 0.3 0.1 12.8 0.3 1.2 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Maf_N PF08383.11 KEG05574.1 - 0.14 11.9 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 Maf N-terminal region Mucin PF01456.17 KEG05575.1 - 0.068 13.2 21.5 1.7 8.6 21.5 2.6 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF2508 PF10704.9 KEG05575.1 - 0.15 12.2 0.3 0.15 12.2 0.3 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2508) Bap31 PF05529.12 KEG05576.1 - 0.032 14.1 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Rax2 PF12768.7 KEG05578.1 - 0.25 10.8 0.1 0.5 9.8 0.1 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Hexokinase_2 PF03727.16 KEG05579.1 - 9.3e-66 221.7 0.0 1.2e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEG05579.1 - 3.1e-60 203.5 0.2 4.6e-60 202.9 0.2 1.3 1 0 0 1 1 1 1 Hexokinase Ecm29 PF13001.7 KEG05580.1 - 0.17 10.5 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser PELOTA_1 PF15608.6 KEG05581.1 - 0.077 12.9 8.3 1 9.3 4.0 2.3 2 0 0 2 2 2 0 PELOTA RNA binding domain PPR_2 PF13041.6 KEG05582.1 - 1.3e-37 127.7 10.4 8.1e-07 29.1 0.3 8.7 4 2 5 9 9 9 8 PPR repeat family PPR PF01535.20 KEG05582.1 - 7.3e-32 107.4 20.9 0.00057 20.0 0.0 11.7 13 1 0 13 13 13 7 PPR repeat PPR_3 PF13812.6 KEG05582.1 - 1.3e-22 79.7 2.6 0.00068 19.7 0.0 6.7 6 2 1 7 7 7 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 KEG05582.1 - 5.6e-19 67.5 8.4 0.023 14.4 0.0 9.8 11 0 0 11 11 11 6 PPR repeat PPR_long PF17177.4 KEG05582.1 - 3.4e-15 56.0 0.3 8.4e-05 22.0 0.1 4.2 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 KEG05582.1 - 0.00018 20.7 0.0 12 5.0 0.0 4.2 2 1 2 4 4 4 3 Evolutionarily conserved signalling intermediate in Toll pathway Bac_small_YrzI PF09501.10 KEG05582.1 - 0.3 11.3 1.1 37 4.5 0.0 2.8 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Ribosomal_L28e PF01778.17 KEG05585.1 - 1.2e-20 74.3 2.2 1.2e-20 74.3 2.2 1.5 1 1 0 1 1 1 1 Ribosomal L28e protein family ApbA PF02558.16 KEG05585.1 - 0.074 12.7 0.9 0.18 11.5 0.0 1.9 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Cyclin_N PF00134.23 KEG05586.1 - 0.061 13.1 0.1 1.5 8.6 0.0 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain DUF1413 PF07205.11 KEG05587.1 - 0.041 13.9 0.1 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1413) Tymo_coat PF00983.18 KEG05587.1 - 0.078 12.8 0.0 10 5.9 0.0 2.8 3 0 0 3 3 3 0 Tymovirus coat protein Repressor_Mnt PF11423.8 KEG05587.1 - 0.094 12.5 2.5 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 Regulatory protein Mnt T4_Rnl2_C PF18043.1 KEG05587.1 - 0.14 12.3 1.5 3 8.1 0.1 2.5 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal Cornifin PF02389.15 KEG05588.1 - 0.0048 17.1 0.5 11 6.3 0.0 3.1 1 1 1 3 3 3 3 Cornifin (SPRR) family Pkinase PF00069.25 KEG05591.1 - 2e-13 50.4 0.0 7.4e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG05591.1 - 6.1e-06 25.7 0.0 2.4e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Lzipper-MIP1 PF14389.6 KEG05591.1 - 0.0051 17.1 0.7 0.0098 16.2 0.7 1.5 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF2205 PF10224.9 KEG05591.1 - 0.22 11.5 0.5 0.45 10.5 0.5 1.5 1 0 0 1 1 1 0 Short coiled-coil protein NUDIX PF00293.28 KEG05593.1 - 7.6e-16 58.4 0.2 1.2e-15 57.7 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain SmpA_OmlA PF04355.13 KEG05596.1 - 0.00079 19.2 0.1 33 4.4 0.0 4.7 4 1 0 5 5 5 4 SmpA / OmlA family Histone_HNS PF00816.21 KEG05597.1 - 0.015 16.1 4.3 0.029 15.2 4.3 1.6 1 0 0 1 1 1 0 H-NS histone family MRP-S31 PF15433.6 KEG05597.1 - 0.18 11.5 3.6 0.21 11.3 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Mucin PF01456.17 KEG05600.1 - 1.3e-06 28.5 8.1 1.3e-06 28.5 8.1 4.0 1 1 1 2 2 2 1 Mucin-like glycoprotein Helicase_C PF00271.31 KEG05601.1 - 9e-05 22.8 0.0 0.00039 20.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG05601.1 - 0.00074 19.3 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_10 PF13673.7 KEG05602.1 - 2.3e-15 56.7 0.1 2.4e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEG05602.1 - 4.2e-11 43.1 0.1 4.8e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEG05602.1 - 5e-09 36.5 0.0 6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG05602.1 - 4.4e-06 26.6 0.0 5.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KEG05602.1 - 6.5e-05 23.0 0.0 8.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEG05602.1 - 0.0013 18.9 0.1 0.0024 18.0 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.6 KEG05602.1 - 0.13 11.6 0.0 0.15 11.5 0.0 1.2 1 1 0 1 1 1 0 GNAT acetyltransferase 2 DUF3074 PF11274.8 KEG05603.1 - 0.016 15.2 1.2 0.027 14.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) DUF3606 PF12244.8 KEG05603.1 - 0.084 12.8 2.8 0.23 11.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) F-box-like_2 PF13013.6 KEG05603.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Ubiquitin_3 PF14836.6 KEG05603.1 - 0.2 11.7 1.5 0.36 10.9 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain DUF3450 PF11932.8 KEG05603.1 - 0.87 8.8 11.1 0.16 11.3 7.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FAM70 PF14967.6 KEG05603.1 - 2.2 7.6 4.1 3 7.2 4.1 1.1 1 0 0 1 1 1 0 FAM70 protein DUF1664 PF07889.12 KEG05603.1 - 3.4 7.7 6.8 5.1 7.2 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Borrelia_P83 PF05262.11 KEG05604.1 - 0.22 10.0 27.4 0.26 9.7 27.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3807 PF12720.7 KEG05604.1 - 4.3 7.6 26.2 6.2 7.1 26.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 KEG05604.1 - 4.6 7.0 28.2 6.5 6.5 28.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KEG05604.1 - 4.9 5.8 23.8 5.2 5.7 23.8 1.0 1 0 0 1 1 1 0 Presenilin Smg8_Smg9 PF10220.9 KEG05604.1 - 6.8 4.9 15.1 7.5 4.7 15.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 MAJIN PF15077.6 KEG05604.1 - 6.8 6.4 15.4 8.6 6.1 15.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein HC2 PF07382.11 KEG05605.1 - 0.63 10.1 36.6 0.8 9.7 36.6 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Peptidase_M8 PF01457.16 KEG05606.1 - 4.6e-103 345.7 4.5 1.1e-54 186.0 0.1 2.0 1 1 1 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG05606.1 - 0.0069 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KEG05606.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin SLAIN PF15301.6 KEG05607.1 - 1.7 7.8 6.6 3.3 6.9 6.6 1.5 1 1 0 1 1 1 0 SLAIN motif-containing family HIP1_clath_bdg PF16515.5 KEG05608.1 - 0.00025 21.6 74.2 0.031 14.9 1.4 6.2 4 2 2 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KEG05608.1 - 0.00026 21.0 26.7 0.031 14.3 0.3 6.3 2 2 3 6 6 6 3 Protein of unknown function (DUF1664) DUF3584 PF12128.8 KEG05608.1 - 0.0023 15.5 4.1 0.0023 15.5 4.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3584) CCDC144C PF14915.6 KEG05608.1 - 0.0047 16.1 8.2 0.0047 16.1 8.2 3.8 3 1 0 3 3 3 1 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 KEG05608.1 - 0.041 13.9 76.3 0.024 14.7 10.5 4.7 3 2 2 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FBD PF08387.10 KEG05608.1 - 0.074 13.0 0.6 83 3.2 0.0 4.0 4 0 0 4 4 4 0 FBD DUF948 PF06103.11 KEG05608.1 - 0.45 10.8 7.8 25 5.2 0.1 4.7 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Glutaredoxin2_C PF04399.13 KEG05608.1 - 0.78 9.6 11.5 1.3 8.8 0.3 4.5 3 3 3 6 6 6 0 Glutaredoxin 2, C terminal domain C_Hendra PF16821.5 KEG05608.1 - 2.1 8.2 16.1 3.1 7.6 6.3 3.5 2 2 1 3 3 3 0 C protein from hendra and measles viruses YojJ PF10372.9 KEG05608.1 - 3.1 8.0 20.0 1.5 9.0 0.8 5.3 4 2 3 7 7 7 0 Bacterial membrane-spanning protein N-terminus DUF1103 PF06513.11 KEG05608.1 - 6.8 6.2 14.7 0.058 13.0 2.7 2.8 3 0 0 3 3 3 0 Repeat of unknown function (DUF1103) Peripla_BP_6 PF13458.6 KEG05611.1 - 1.1e-10 41.7 0.0 2.5e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein RHSP PF07999.11 KEG05612.1 - 6.6e-98 328.4 0.2 1.1e-97 327.6 0.2 1.4 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.6 KEG05612.1 - 0.042 13.2 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Macro-like domain Cas_Cas1 PF01867.16 KEG05612.1 - 0.052 12.7 0.1 4.3 6.4 0.4 2.2 2 0 0 2 2 2 0 CRISPR associated protein Cas1 WSD PF15613.6 KEG05612.1 - 1.6 9.3 5.4 2.2 8.8 0.2 3.3 3 1 1 4 4 4 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Bacillus_PapR PF05968.11 KEG05613.1 - 7.4 6.5 6.1 1.3 9.0 2.1 1.8 2 0 0 2 2 2 0 Bacillus PapR protein EF-hand_7 PF13499.6 KEG05615.1 - 2.1e-11 44.1 0.7 2.2e-07 31.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG05615.1 - 2.1e-09 37.1 0.0 0.00057 19.7 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KEG05615.1 - 5.5e-09 35.3 0.7 0.032 14.1 0.0 4.1 4 1 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 KEG05615.1 - 4.4e-08 33.3 0.0 0.0028 17.9 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEG05615.1 - 4.2e-06 25.9 0.1 0.57 9.9 0.0 3.8 4 0 0 4 4 4 2 EF hand DUF2087 PF09860.9 KEG05615.1 - 0.0062 16.7 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2087) DUF3216 PF11505.8 KEG05615.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) RNA_pol_Rpb4 PF03874.16 KEG05615.1 - 0.13 12.6 0.1 10 6.5 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 GPHH PF16905.5 KEG05615.1 - 0.17 11.7 0.0 3.2 7.6 0.0 2.7 3 1 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated WD40_alt PF14077.6 KEG05616.1 - 0.71 9.8 3.8 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif ribosomal_L24 PF17136.4 KEG05617.1 - 0.00063 20.1 0.1 0.0013 19.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF1016_N PF17761.1 KEG05617.1 - 0.0013 18.9 0.2 0.002 18.3 0.2 1.3 1 0 0 1 1 1 1 DUF1016 N-terminal domain KOW PF00467.29 KEG05617.1 - 0.0093 15.9 1.1 0.0093 15.9 1.1 2.1 2 0 0 2 2 2 1 KOW motif Lebercilin PF15619.6 KEG05619.1 - 0.096 12.3 2.5 0.21 11.2 2.5 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Motile_Sperm PF00635.26 KEG05620.1 - 2.4e-13 49.9 0.0 4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.6 KEG05620.1 - 0.0071 16.5 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like SieB PF14163.6 KEG05621.1 - 2.2 7.7 4.1 2.8 7.4 4.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B SPC12 PF06645.13 KEG05621.1 - 2.8 8.1 4.9 41 4.4 4.9 2.2 1 1 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Peripla_BP_6 PF13458.6 KEG05624.1 - 0.0019 17.9 0.4 0.026 14.2 0.4 2.4 1 1 0 1 1 1 1 Periplasmic binding protein cNMP_binding PF00027.29 KEG05626.1 - 3.7e-19 68.6 0.2 3e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Bromodomain PF00439.25 KEG05627.1 - 9.9e-05 22.3 0.0 0.00012 22.1 0.0 1.1 1 0 0 1 1 1 1 Bromodomain Barwin PF00967.17 KEG05627.1 - 0.034 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Barwin family Nudix_hydro PF18290.1 KEG05628.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain LPP PF04728.13 KEG05631.1 - 0.028 14.8 2.1 0.063 13.7 2.1 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TSC22 PF01166.18 KEG05631.1 - 0.036 14.4 2.1 0.036 14.4 2.1 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family CLZ PF16526.5 KEG05631.1 - 0.14 12.5 2.2 0.26 11.7 2.2 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Chibby PF14645.6 KEG05631.1 - 0.25 11.8 6.3 0.25 11.7 4.0 1.9 1 1 1 2 2 2 0 Chibby family DUF3450 PF11932.8 KEG05631.1 - 0.28 10.5 8.1 0.48 9.7 5.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KEG05631.1 - 3.1 8.3 12.8 0.21 12.1 5.4 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KEG05631.1 - 7.9 6.3 10.2 0.7 9.7 4.7 1.9 1 1 1 2 2 2 0 Septum formation initiator Glyco_hydro_125 PF06824.11 KEG05632.1 - 1.7e-33 116.1 0.0 2e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Hydrolase_3 PF08282.12 KEG05633.1 - 9.9e-24 84.4 0.0 1.1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEG05633.1 - 0.00082 19.4 0.0 0.002 18.2 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEG05633.1 - 0.0026 17.3 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KEG05633.1 - 0.0036 17.6 0.1 0.0099 16.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEG05634.1 - 5.2e-29 101.8 3.1 1e-15 58.2 0.1 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEG05634.1 - 1.3e-06 28.9 6.6 0.0011 19.3 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEG05634.1 - 2.5e-05 23.9 0.1 0.043 13.4 0.0 2.0 1 1 1 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 KEG05634.1 - 2.8e-05 24.6 0.2 0.14 12.5 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase UQ_con PF00179.26 KEG05635.1 - 1.1e-19 70.4 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF452 PF04301.13 KEG05635.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF452) Peripla_BP_6 PF13458.6 KEG05636.1 - 8e-08 32.3 0.1 2e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein DUF592 PF04574.13 KEG05636.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF592) CLTH PF10607.9 KEG05638.1 - 0.079 12.8 0.0 16 5.4 0.0 2.6 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Amidase_5 PF05382.13 KEG05638.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase Fez1 PF06818.15 KEG05638.1 - 0.6 10.5 26.4 0.2 12.1 4.7 2.4 2 0 0 2 2 2 0 Fez1 DUF1203 PF06718.11 KEG05638.1 - 0.73 10.1 4.5 4.8 7.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1203) DUF4407 PF14362.6 KEG05638.1 - 2.1 7.6 24.0 0.6 9.4 13.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KEG05638.1 - 4.8 7.7 5.2 10 6.6 0.2 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 KEG05638.1 - 9.8 6.6 26.3 7.6 7.0 5.9 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF569 PF04601.13 KEG05639.1 - 0.0024 17.6 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF569) RNase_H PF00075.24 KEG05642.1 - 0.00015 21.9 0.0 0.00024 21.3 0.0 1.3 1 1 0 1 1 1 1 RNase H DUF1088 PF06469.11 KEG05643.1 - 0.031 13.9 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) ANAPC_CDC26 PF10471.9 KEG05643.1 - 0.041 14.7 0.7 0.086 13.7 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 SBP_bac_11 PF13531.6 KEG05644.1 - 0.0008 19.2 2.8 0.0012 18.6 2.3 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Dpy-30 PF05186.13 KEG05644.1 - 0.0032 17.1 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif UPF0560 PF10577.9 KEG05644.1 - 0.37 9.2 8.2 0.45 9.0 8.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 KEG05644.1 - 1.2 8.7 13.5 1.7 8.2 13.5 1.3 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 KEG05646.1 - 0.84 7.7 7.3 1.1 7.3 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CALCOCO1 PF07888.11 KEG05646.1 - 1.6 7.5 6.7 2.4 7.0 6.7 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GREB1 PF15782.5 KEG05646.1 - 2.9 4.9 6.7 4.2 4.4 6.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer M20_dimer PF07687.14 KEG05648.1 - 1e-20 73.6 0.0 2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KEG05648.1 - 0.00012 21.9 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mucin PF01456.17 KEG05649.1 - 9.9 6.1 29.6 0.64 10.0 8.1 2.8 2 1 0 2 2 2 0 Mucin-like glycoprotein Oleosin PF01277.17 KEG05652.1 - 0.21 11.3 3.9 0.3 10.8 3.9 1.3 1 0 0 1 1 1 0 Oleosin CcmB PF03379.13 KEG05653.1 - 0.029 13.9 0.3 0.04 13.4 0.3 1.1 1 0 0 1 1 1 0 CcmB protein Mucin PF01456.17 KEG05654.1 - 0.0027 17.7 28.3 0.0027 17.7 28.3 3.9 2 2 0 2 2 2 1 Mucin-like glycoprotein GREB1 PF15782.5 KEG05655.1 - 3.8 4.5 13.6 5.5 4.0 13.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 KEG05655.1 - 8.3 6.3 7.0 14 5.6 7.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_M8 PF01457.16 KEG05656.1 - 2.7e-32 112.2 0.7 3.1e-32 112.0 0.7 1.0 1 0 0 1 1 1 1 Leishmanolysin CCT_2 PF09425.10 KEG05660.1 - 0.21 11.5 6.0 0.88 9.5 6.0 2.0 1 1 0 1 1 1 0 Divergent CCT motif Mucin PF01456.17 KEG05661.1 - 1.3e-05 25.2 1.5 0.0017 18.3 0.2 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein Phage_GPL PF05926.11 KEG05661.1 - 0.077 13.0 0.6 0.18 11.8 0.6 1.6 1 0 0 1 1 1 0 Phage head completion protein (GPL) DUF2514 PF10721.9 KEG05661.1 - 0.49 10.4 7.1 0.19 11.7 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Capsid_VP7 PF17071.5 KEG05663.1 - 0.022 14.1 0.3 0.024 13.9 0.3 1.0 1 0 0 1 1 1 0 Outer capsid protein VP7 Collagen PF01391.18 KEG05664.1 - 0.017 14.9 9.0 0.017 14.9 9.0 3.8 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) ABC_ATPase PF09818.9 KEG05668.1 - 1.5e-125 419.5 0.0 1.9e-125 419.2 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KEG05668.1 - 0.0028 18.2 0.0 0.0054 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PAC2 PF09754.9 KEG05668.1 - 0.023 14.7 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 PAC2 family ABC_tran PF00005.27 KEG05668.1 - 0.071 13.6 0.1 4 8.0 0.1 2.4 1 1 0 1 1 1 0 ABC transporter GspH PF12019.8 KEG05669.1 - 0.0025 18.2 0.2 0.42 11.0 0.0 2.3 1 1 0 2 2 2 2 Type II transport protein GspH FOXP-CC PF16159.5 KEG05670.1 - 0.1 13.2 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 FOXP coiled-coil domain Candida_ALS PF05792.13 KEG05670.1 - 0.33 11.6 4.4 1.4 9.5 4.4 2.0 1 1 0 1 1 1 0 Candida agglutinin-like (ALS) LRR_4 PF12799.7 KEG05672.1 - 3.9e-21 74.8 6.0 0.0019 18.6 0.0 6.6 5 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG05672.1 - 8.9e-14 51.0 7.0 0.0007 19.3 0.1 5.4 3 1 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 KEG05672.1 - 3.4e-10 39.1 7.4 0.21 11.7 0.0 8.3 8 0 0 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.6 KEG05672.1 - 0.013 15.0 0.4 6.9 6.1 0.0 3.5 3 1 1 4 4 4 0 Leucine-rich repeat LRR_1 PF00560.33 KEG05672.1 - 0.036 14.6 12.0 10 7.1 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich Repeat Mito_carr PF00153.27 KEG05673.1 - 1.4e-57 191.6 1.4 2.7e-20 72.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CDGSH PF09360.10 KEG05674.1 - 8.6e-12 45.1 1.2 2.8e-10 40.3 0.1 2.7 3 0 0 3 3 3 2 Iron-binding zinc finger CDGSH type PCI PF01399.27 KEG05675.1 - 3.9e-05 24.1 0.2 0.00022 21.7 0.3 2.2 3 0 0 3 3 3 1 PCI domain Sigma54_CBD PF04963.13 KEG05675.1 - 0.35 10.7 1.3 0.56 10.0 0.4 1.7 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain TPR_10 PF13374.6 KEG05677.1 - 0.083 12.8 1.7 0.14 12.0 1.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat IF-2B PF01008.17 KEG05678.1 - 1.4e-67 227.9 0.3 1.6e-67 227.7 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PepSY_2 PF13670.6 KEG05678.1 - 0.056 13.4 1.6 0.14 12.2 1.6 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Mcl1_mid PF12341.8 KEG05679.1 - 5.5e-41 140.8 0.1 1.1e-40 139.9 0.0 1.5 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region Spt5_N PF11942.8 KEG05679.1 - 0.0031 18.5 10.3 0.0031 18.5 10.3 2.5 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KIP1 PF07765.12 KEG05679.1 - 0.061 13.5 0.3 0.14 12.3 0.3 1.6 1 1 0 1 1 1 0 KIP1-like protein Tub_N PF16322.5 KEG05679.1 - 1.6 9.1 11.6 2.3 8.6 11.6 1.2 1 0 0 1 1 1 0 Tubby N-terminal vATP-synt_AC39 PF01992.16 KEG05682.1 - 2.2e-87 293.7 0.1 2.4e-87 293.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit RBB1NT PF08169.11 KEG05683.1 - 0.023 14.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 RBB1NT (NUC162) domain EphA2_TM PF14575.6 KEG05684.1 - 0.011 16.6 0.0 0.017 16.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KEG05684.1 - 0.028 14.7 0.2 0.038 14.2 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LAX PF15681.5 KEG05684.1 - 0.066 12.0 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X CD34_antigen PF06365.12 KEG05684.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF202 PF02656.15 KEG05684.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Amnionless PF14828.6 KEG05684.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4690 PF15756.5 KEG05684.1 - 0.14 12.8 0.2 0.14 12.8 0.2 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Syndecan PF01034.20 KEG05684.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 KEG05684.1 - 4.4 7.8 4.8 12 6.4 4.8 1.7 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SUIM_assoc PF16619.5 KEG05685.1 - 2 8.6 10.4 2.4 8.3 2.1 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 KEG05689.1 - 5.1e-30 104.7 0.0 5.9e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG05689.1 - 8.2e-14 51.5 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG05689.1 - 0.0016 17.9 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Ribosomal_L19e PF01280.20 KEG05691.1 - 3.1e-62 208.9 13.2 3.1e-62 208.9 13.2 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2202 PF09968.9 KEG05691.1 - 0.008 16.0 1.3 0.008 16.0 1.3 1.5 2 0 0 2 2 2 1 Uncharacterized protein domain (DUF2202) Macoilin PF09726.9 KEG05691.1 - 0.048 12.2 15.7 0.051 12.1 15.7 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KEG05691.1 - 8.9 5.0 6.2 9.4 4.9 6.2 1.2 1 0 0 1 1 1 0 Presenilin Penicil_amidase PF01804.18 KEG05692.1 - 5.4e-11 42.2 0.0 5.8e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase Trp_oprn_chp PF09534.10 KEG05693.1 - 0.0005 19.9 0.5 0.0006 19.7 0.5 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gpr1_Fun34_YaaH PF01184.19 KEG05693.1 - 0.0068 16.0 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CBM_15 PF03426.14 KEG05693.1 - 0.04 13.5 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Med3 PF11593.8 KEG05695.1 - 4.3 6.4 11.0 4.3 6.4 11.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LMBR1 PF04791.16 KEG05697.1 - 1.4 7.7 13.2 1.4 7.8 13.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Menin PF05053.13 KEG05697.1 - 3.2 6.0 19.0 5.3 5.3 19.0 1.4 1 0 0 1 1 1 0 Menin AFOR_C PF01314.18 KEG05699.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Peripla_BP_6 PF13458.6 KEG05699.1 - 0.16 11.6 2.4 0.34 10.5 1.1 1.9 1 1 1 2 2 2 0 Periplasmic binding protein GIDE PF12483.8 KEG05699.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 E3 Ubiquitin ligase ABC_tran PF00005.27 KEG05700.1 - 0.13 12.8 0.6 3.6 8.1 0.2 2.4 2 1 1 3 3 3 0 ABC transporter EMG1 PF03587.14 KEG05704.1 - 5.2e-57 192.6 0.0 7e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Tim44 PF04280.15 KEG05705.1 - 0.036 14.2 0.2 0.042 14.0 0.2 1.2 1 0 0 1 1 1 0 Tim44-like domain NAPRTase_N PF17767.1 KEG05705.1 - 0.084 13.3 0.0 0.09 13.2 0.0 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DDE_Tnp_1_6 PF13751.6 KEG05705.1 - 0.1 12.8 0.8 0.13 12.4 0.7 1.3 1 1 0 1 1 1 0 Transposase DDE domain Mucin PF01456.17 KEG05707.1 - 0.013 15.5 4.6 0.02 14.9 4.6 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein RR_TM4-6 PF06459.12 KEG05707.1 - 0.68 9.7 4.2 0.71 9.6 4.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 KEG05707.1 - 2.8 6.0 6.0 2.9 5.9 6.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCDC144C PF14915.6 KEG05708.1 - 0.00045 19.4 1.8 0.00058 19.1 1.8 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF4482 PF14818.6 KEG05708.1 - 0.00065 20.6 0.1 0.00076 20.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) SHE3 PF17078.5 KEG05708.1 - 0.0012 18.6 1.3 0.0027 17.5 1.4 1.4 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 KEG05708.1 - 0.0014 19.1 7.7 0.0034 17.9 4.1 2.0 1 1 1 2 2 2 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KEG05708.1 - 0.0018 18.3 6.4 0.013 15.5 6.4 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KEG05708.1 - 0.0026 17.1 1.7 0.12 11.6 0.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) DivIC PF04977.15 KEG05708.1 - 0.0048 16.6 2.6 0.21 11.4 0.8 2.2 2 0 0 2 2 2 1 Septum formation initiator HAUS-augmin3 PF14932.6 KEG05708.1 - 0.0051 16.4 0.2 0.0062 16.2 0.2 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ZapB PF06005.12 KEG05708.1 - 0.0051 17.2 2.4 0.076 13.5 0.6 2.3 2 1 0 2 2 2 1 Cell division protein ZapB TolA_bind_tri PF16331.5 KEG05708.1 - 0.0075 16.3 0.7 0.013 15.6 0.7 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 KEG05708.1 - 0.0091 16.1 3.1 1.3 9.0 0.3 2.1 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KEG05708.1 - 0.0097 14.8 0.2 0.01 14.7 0.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.6 KEG05708.1 - 0.023 14.4 2.0 0.031 14.0 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 KEG05708.1 - 0.035 14.1 0.8 0.63 10.1 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KEG05708.1 - 0.038 14.6 4.6 0.1 13.2 4.6 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_3 PF13758.6 KEG05708.1 - 0.053 13.6 0.2 0.43 10.7 0.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit TraF_2 PF13729.6 KEG05708.1 - 0.053 12.9 0.2 0.064 12.6 0.2 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Tektin PF03148.14 KEG05708.1 - 0.059 12.1 3.1 0.98 8.1 1.3 2.0 1 1 1 2 2 2 0 Tektin family Chlor_dismutase PF06778.12 KEG05708.1 - 0.061 12.9 0.1 0.08 12.5 0.1 1.1 1 0 0 1 1 1 0 Chlorite dismutase Snapin_Pallidin PF14712.6 KEG05708.1 - 0.064 13.7 1.7 0.49 10.9 0.4 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.17 KEG05708.1 - 0.073 13.0 1.9 2.3 8.1 0.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KEG05708.1 - 0.082 13.5 3.8 0.23 12.0 1.8 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4472 PF14739.6 KEG05708.1 - 0.092 13.5 2.1 0.24 12.1 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 KEG05708.1 - 0.096 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PI3K_P85_iSH2 PF16454.5 KEG05708.1 - 0.12 12.0 1.4 0.86 9.2 0.6 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc24 PF08286.11 KEG05708.1 - 0.16 12.2 3.4 0.88 9.8 1.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KEG05708.1 - 0.19 11.7 3.6 1.1 9.2 1.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KEG05708.1 - 0.31 11.7 1.8 1 10.0 0.9 2.1 1 1 1 2 2 2 0 SlyX DUF4140 PF13600.6 KEG05708.1 - 0.41 11.1 4.0 8.6 6.9 4.0 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) JIP_LZII PF16471.5 KEG05708.1 - 1.1 9.4 8.1 3.1 8.0 3.5 2.6 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Med21 PF11221.8 KEG05708.1 - 1.4 9.1 4.9 1.2 9.3 2.0 1.9 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF2559 PF10832.8 KEG05708.1 - 1.6 8.9 4.9 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) Kinesin PF00225.23 KEG05709.1 - 2.3e-27 95.8 0.0 2.8e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG05709.1 - 4.9e-15 55.7 0.0 9.6e-15 54.8 0.0 1.4 1 1 0 1 1 1 1 Microtubule binding Acetyltransf_1 PF00583.25 KEG05710.1 - 4.7e-13 49.4 0.0 8.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG05710.1 - 4.5e-07 29.8 0.2 8.1e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG05710.1 - 7.7e-07 29.0 0.1 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 KEG05710.1 - 3e-06 27.5 0.0 6.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEG05710.1 - 0.005 16.9 0.1 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KEG05710.1 - 0.05 13.1 0.6 0.08 12.4 0.2 1.5 1 1 1 2 2 2 0 Putative acetyl-transferase CRPA PF05745.11 KEG05711.1 - 0.027 14.5 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tyr_Deacylase PF02580.16 KEG05713.1 - 1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF641 PF04859.12 KEG05715.1 - 0.00058 20.2 3.4 0.00058 20.2 3.4 3.3 3 1 0 3 3 3 1 Plant protein of unknown function (DUF641) FliD_C PF07195.12 KEG05715.1 - 0.0017 17.8 0.2 0.0017 17.8 0.2 2.4 2 1 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Med9 PF07544.13 KEG05715.1 - 0.03 14.4 0.3 0.03 14.4 0.3 3.9 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 KEG05715.1 - 0.12 10.2 7.8 1.4 6.7 3.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Kinesin_assoc PF16183.5 KEG05715.1 - 0.14 12.3 6.7 0.83 9.8 1.0 3.6 2 2 0 2 2 2 0 Kinesin-associated eIF-4B PF06273.11 KEG05715.1 - 1.1 8.3 14.2 0.083 11.9 1.0 2.7 3 0 0 3 3 3 0 Plant specific eukaryotic initiation factor 4B DUF4446 PF14584.6 KEG05715.1 - 1.6 8.7 8.9 3 7.8 0.8 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) AAA_13 PF13166.6 KEG05715.1 - 2.6 6.6 12.7 0.78 8.3 0.4 2.3 2 0 0 2 2 2 0 AAA domain MPS2 PF17060.5 KEG05715.1 - 4.2 6.5 9.8 0.091 12.0 2.5 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF16 PF01519.16 KEG05715.1 - 4.4 7.8 17.9 2 9.0 2.6 3.5 3 1 1 4 4 4 0 Protein of unknown function DUF16 Aa_trans PF01490.18 KEG05717.1 - 6.2e-16 58.1 2.1 7.3e-16 57.9 2.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG05717.1 - 7.2e-08 31.9 3.0 8.5e-08 31.6 3.0 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Mucin PF01456.17 KEG05719.1 - 4e-08 33.3 7.4 4e-08 33.3 7.4 4.0 2 1 1 3 3 3 2 Mucin-like glycoprotein TUTF7_u4 PF16631.5 KEG05719.1 - 0.55 10.9 5.8 1.6 9.4 5.8 1.8 1 0 0 1 1 1 0 Unstructured region 4 on terminal uridylyltransferase 7 Flagellin_C PF00700.21 KEG05719.1 - 0.97 9.8 5.9 0.82 10.1 0.2 3.1 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region IF-2B PF01008.17 KEG05720.1 - 1.7e-32 112.8 0.1 4.6e-32 111.4 0.1 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Glyco_transf_10 PF00852.19 KEG05722.1 - 3.2e-19 69.3 0.0 8.8e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term PreAtp-grasp PF18604.1 KEG05722.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Pre ATP-grasp domain DEAD PF00270.29 KEG05723.1 - 7.7e-45 152.8 0.3 1.1e-44 152.3 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG05723.1 - 1.4e-28 99.4 1.1 7.9e-28 97.0 1.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KEG05723.1 - 0.00039 20.8 0.4 0.00067 20.0 0.4 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 KEG05723.1 - 0.00071 18.9 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 KEG05723.1 - 0.012 15.4 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEG05723.1 - 0.078 13.2 0.4 0.22 11.8 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEG05723.1 - 0.088 13.2 0.4 0.53 10.7 0.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SLED PF12140.8 KEG05724.1 - 0.13 12.8 0.3 2 8.9 0.0 2.1 1 1 1 2 2 2 0 SLED domain DUF3656 PF12392.8 KEG05724.1 - 0.48 11.1 2.4 0.97 10.1 2.4 1.5 1 0 0 1 1 1 0 Collagenase Peripla_BP_6 PF13458.6 KEG05725.1 - 0.01 15.6 3.7 0.066 12.9 1.5 2.7 2 1 0 2 2 2 0 Periplasmic binding protein DUF5308 PF17233.2 KEG05727.1 - 2.3 8.4 11.2 2.4 8.4 11.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Spt20 PF12090.8 KEG05727.1 - 3.9 7.0 20.1 3.9 7.0 20.1 1.0 1 0 0 1 1 1 0 Spt20 family PBP_sp32 PF07222.12 KEG05727.1 - 6.4 6.1 21.5 6.9 6.0 21.5 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SMC_ScpB PF04079.16 KEG05731.1 - 0.052 13.2 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB LNP1 PF15419.6 KEG05733.1 - 0.012 15.9 1.0 0.015 15.6 1.0 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 CD34_antigen PF06365.12 KEG05734.1 - 0.00051 19.7 0.3 0.33 10.5 0.0 2.2 2 0 0 2 2 2 2 CD34/Podocalyxin family EphA2_TM PF14575.6 KEG05734.1 - 0.0013 19.6 0.0 0.0021 18.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KEG05734.1 - 0.012 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless S1FA PF04689.13 KEG05734.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA LAX PF15681.5 KEG05734.1 - 0.014 14.2 0.3 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Lymphocyte activation family X SpoIIIAH PF12685.7 KEG05734.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein FAM101 PF15068.6 KEG05734.1 - 0.032 14.2 1.0 0.048 13.6 1.0 1.3 1 0 0 1 1 1 0 FAM101 family DUF4006 PF13179.6 KEG05734.1 - 0.091 12.7 0.3 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Shisa PF13908.6 KEG05734.1 - 0.12 12.6 2.0 0.23 11.7 0.1 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator STOP PF05217.12 KEG05735.1 - 0.002 18.4 10.4 0.0076 16.5 10.4 2.1 1 1 0 1 1 1 1 STOP protein APC_r PF05923.12 KEG05736.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 APC repeat Mucin PF01456.17 KEG05737.1 - 0.002 18.1 0.7 0.0035 17.3 0.1 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein T3SSipB PF16535.5 KEG05737.1 - 0.026 15.0 2.5 0.026 15.0 2.5 3.5 3 1 1 4 4 4 0 Type III cell invasion protein SipB CRR7 PF12095.8 KEG05737.1 - 0.24 11.9 1.1 0.7 10.4 1.1 1.8 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF5563 PF17718.1 KEG05737.1 - 1.3 8.5 7.6 0.34 10.4 1.0 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5563) PKD_channel PF08016.12 KEG05739.1 - 2.7e-06 26.4 10.7 4.1e-06 25.8 10.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KEG05739.1 - 0.00049 19.4 12.3 0.00049 19.4 12.3 1.7 2 0 0 2 2 2 1 Ion transport protein Citrate_synt PF00285.21 KEG05740.1 - 7.4e-96 321.4 0.0 8.8e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain BPS1 PF05633.11 KEG05741.1 - 0.046 12.7 2.6 0.081 11.9 2.6 1.3 1 0 0 1 1 1 0 Protein BYPASS1-related Fcf1 PF04900.12 KEG05742.1 - 2.6e-30 104.7 3.1 4.9e-30 103.9 3.1 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KEG05742.1 - 5e-13 49.4 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 PIN like domain TPR_6 PF13174.6 KEG05743.1 - 0.024 15.2 0.3 0.12 13.1 0.3 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG05743.1 - 0.025 14.7 0.4 0.1 12.8 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG05743.1 - 0.065 13.1 0.3 0.19 11.6 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEG05743.1 - 0.081 12.9 0.7 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEG05743.1 - 0.096 13.4 3.2 0.17 12.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Vta1_C PF18097.1 KEG05744.1 - 1.8e-14 53.2 4.9 3.1e-14 52.4 4.9 1.3 1 0 0 1 1 1 1 Vta1 C-terminal domain Vta1 PF04652.16 KEG05744.1 - 4.8e-08 33.1 0.1 8.2e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Vta1 like DUF1178 PF06676.11 KEG05745.1 - 6.4 7.2 10.0 0.45 10.9 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) GREB1 PF15782.5 KEG05746.1 - 2.9 4.9 11.2 4.3 4.3 11.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAD PF05557.13 KEG05748.1 - 0.00041 18.9 36.8 0.00047 18.7 36.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein NPV_P10 PF05531.12 KEG05748.1 - 0.0021 18.5 8.5 0.78 10.2 0.6 3.3 1 1 3 4 4 4 2 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KEG05748.1 - 0.012 15.8 47.2 0.27 11.4 37.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 KEG05748.1 - 0.018 13.1 15.3 0.045 11.7 15.3 1.6 1 1 0 1 1 1 0 Prominin Bcr-Abl_Oligo PF09036.10 KEG05748.1 - 0.052 13.6 18.8 2.1 8.4 0.4 4.6 1 1 3 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain AIP3 PF03915.13 KEG05748.1 - 0.065 12.3 22.6 0.13 11.3 22.6 1.6 1 1 0 1 1 1 0 Actin interacting protein 3 Phage_GP20 PF06810.11 KEG05748.1 - 0.096 12.5 19.8 1.1 9.1 7.1 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 FPP PF05911.11 KEG05748.1 - 0.1 10.8 35.5 0.27 9.4 35.5 1.6 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.9 KEG05748.1 - 0.17 12.2 21.1 0.88 9.9 5.0 3.3 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 KEG05748.1 - 0.39 11.2 29.8 0.29 11.6 10.7 2.3 1 1 1 2 2 2 0 Spectrin repeat Vps53_N PF04100.12 KEG05748.1 - 0.54 9.2 18.7 0.16 10.9 7.9 2.2 1 1 1 2 2 2 0 Vps53-like, N-terminal Uds1 PF15456.6 KEG05748.1 - 0.62 10.2 31.2 6.3 7.0 5.6 3.7 1 1 2 3 3 3 0 Up-regulated During Septation FTA4 PF13093.6 KEG05748.1 - 0.72 9.7 28.3 1.7 8.5 9.9 2.4 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3584 PF12128.8 KEG05748.1 - 0.85 7.1 28.9 1.3 6.4 28.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_C78 PF07910.13 KEG05748.1 - 0.9 9.0 4.9 13 5.2 0.8 2.4 1 1 0 2 2 2 0 Peptidase family C78 BST2 PF16716.5 KEG05748.1 - 1 10.0 34.1 6.4 7.4 18.3 3.5 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF1843 PF08898.10 KEG05748.1 - 1.3 9.6 18.8 2.6 8.6 0.5 4.7 3 2 1 5 5 4 0 Domain of unknown function (DUF1843) FliD_N PF02465.18 KEG05748.1 - 1.3 9.7 14.0 7.4 7.3 5.9 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Occludin_ELL PF07303.13 KEG05748.1 - 2.2 9.1 22.0 16 6.3 8.9 2.8 1 1 1 2 2 2 0 Occludin homology domain DUF5129 PF17173.4 KEG05748.1 - 2.3 7.2 13.1 2.9 6.9 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5129) Fib_alpha PF08702.10 KEG05748.1 - 3.3 7.9 19.0 6.2 7.0 13.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HemX PF04375.14 KEG05748.1 - 3.8 6.7 29.8 3.9 6.7 10.0 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FUSC PF04632.12 KEG05748.1 - 3.8 5.9 15.2 5 5.5 15.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tex_N PF09371.10 KEG05748.1 - 5.9 6.5 21.8 4.5 6.9 6.3 2.6 1 1 1 2 2 2 0 Tex-like protein N-terminal domain PIN_8 PF18476.1 KEG05748.1 - 6.1 6.6 22.2 1.4 8.7 10.5 2.0 1 1 1 2 2 2 0 PIN like domain DUF1664 PF07889.12 KEG05748.1 - 8.5 6.4 15.2 5.5 7.0 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KEG05749.1 - 0.00015 22.1 16.5 2.3 8.7 2.0 6.2 3 2 4 7 7 7 2 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 KEG05749.1 - 0.025 15.3 63.1 0.19 12.5 11.8 5.2 1 1 4 5 5 5 0 Occludin homology domain AIP3 PF03915.13 KEG05749.1 - 0.12 11.4 46.9 1.4 8.0 17.7 3.9 1 1 2 3 3 3 0 Actin interacting protein 3 MAD PF05557.13 KEG05749.1 - 0.15 10.4 86.2 0.037 12.4 40.9 2.8 1 1 2 3 3 3 0 Mitotic checkpoint protein BLOC1_2 PF10046.9 KEG05749.1 - 0.41 11.0 54.3 0.17 12.2 4.7 6.4 1 1 7 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 KEG05749.1 - 0.69 10.7 31.1 4.2 8.1 0.6 6.4 1 1 2 3 3 2 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 KEG05749.1 - 0.83 9.9 52.9 0.11 12.7 5.7 4.7 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Fungal_lectin_2 PF18647.1 KEG05749.1 - 1.9 9.0 13.6 19 5.8 0.2 3.7 2 1 1 3 3 3 0 Alpha-galactosyl-binding fungal lectin DUF5600 PF18150.1 KEG05749.1 - 4.5 7.9 20.5 0.32 11.6 0.6 4.3 1 1 1 4 4 4 0 Domain of unknown function (DUF5600) LtuB PF17455.2 KEG05749.1 - 5.1 7.8 41.0 0.064 13.9 3.6 7.3 2 2 5 7 7 7 0 Late transcription unit B Phage_GP20 PF06810.11 KEG05749.1 - 6.7 6.5 46.3 4.6 7.0 2.5 5.5 1 1 3 5 5 5 0 Phage minor structural protein GP20 DUF3584 PF12128.8 KEG05749.1 - 9.6 3.6 68.3 4.3 4.7 28.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Mucin PF01456.17 KEG05753.1 - 0.0001 22.3 10.7 0.0001 22.3 10.7 2.1 1 1 1 2 2 2 1 Mucin-like glycoprotein Alanine_zipper PF11839.8 KEG05753.1 - 0.011 16.0 16.6 0.011 16.0 16.6 3.5 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF948 PF06103.11 KEG05753.1 - 0.062 13.6 2.7 0.1 12.9 0.9 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KEG05753.1 - 0.085 12.2 4.2 0.1 12.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) dCache_2 PF08269.11 KEG05753.1 - 0.37 9.9 1.1 0.55 9.4 1.1 1.2 1 0 0 1 1 1 0 Cache domain Syntaxin-6_N PF09177.11 KEG05753.1 - 0.52 10.9 4.9 1.5 9.4 4.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 KEG05753.1 - 0.97 10.1 3.9 2.1 9.0 2.9 2.2 1 1 1 2 2 2 0 SlyX Spc7 PF08317.11 KEG05753.1 - 1.3 7.8 6.8 2.1 7.2 6.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF572 PF04502.13 KEG05753.1 - 2 8.0 11.5 2.6 7.6 11.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GARP PF16731.5 KEG05754.1 - 0.012 15.3 11.0 0.016 14.9 11.0 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Sec8_exocyst PF04048.14 KEG05754.1 - 0.031 14.2 0.2 0.051 13.5 0.2 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF2969 PF11184.8 KEG05754.1 - 0.1 13.0 1.0 0.22 12.0 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2969) Mucin PF01456.17 KEG05754.1 - 0.68 9.9 10.4 1.5 8.8 10.4 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein Cytochrom_C PF00034.21 KEG05755.1 - 2.9e-10 41.1 0.0 3.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KEG05755.1 - 9.6e-05 22.6 1.3 0.00077 19.7 1.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF3882 PF07066.11 KEG05756.1 - 0.089 12.9 1.0 38 4.3 0.1 3.4 3 1 0 3 3 3 0 Lactococcus phage M3 protein Peripla_BP_6 PF13458.6 KEG05757.1 - 0.029 14.1 0.1 0.056 13.1 0.1 1.4 1 1 0 1 1 1 0 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG05758.1 - 0.00023 20.8 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Orthoreo_P10 PF07204.11 KEG05758.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Tweety PF04906.13 KEG05758.1 - 0.043 12.5 0.0 0.047 12.3 0.0 1.0 1 0 0 1 1 1 0 Tweety Glycophorin_A PF01102.18 KEG05758.1 - 0.07 13.4 0.0 0.077 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 KEG05758.1 - 0.16 12.8 0.0 0.22 12.5 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4514 PF14986.6 KEG05758.1 - 0.19 11.7 1.3 0.35 10.9 1.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4514) SUI1 PF01253.22 KEG05759.1 - 4.3e-20 72.0 0.0 5.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 MTS PF05175.14 KEG05760.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_S8 PF00410.19 KEG05761.1 - 5e-21 75.0 0.0 6.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Mucin PF01456.17 KEG05764.1 - 1.5e-07 31.5 9.4 1.5e-07 31.5 9.4 4.2 3 1 0 3 3 3 1 Mucin-like glycoprotein DUF2277 PF10041.9 KEG05764.1 - 0.027 14.8 0.1 0.027 14.8 0.1 4.5 3 3 1 4 4 4 0 Uncharacterized conserved protein (DUF2277) GARP PF16731.5 KEG05764.1 - 0.11 12.2 48.6 0.26 10.9 9.2 3.3 3 0 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Spc7 PF08317.11 KEG05764.1 - 0.48 9.3 10.9 0.45 9.3 0.2 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 KEG05764.1 - 0.51 7.8 16.5 0.55 7.7 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3829 PF12889.7 KEG05764.1 - 4.3 6.7 13.1 9 5.7 7.1 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) ChaC PF04752.12 KEG05765.1 - 6.1e-13 49.2 0.1 6.4e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 ChaC-like protein Peripla_BP_6 PF13458.6 KEG05774.1 - 0.00013 21.8 0.1 0.00023 20.9 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein Peripla_BP_6 PF13458.6 KEG05778.1 - 9.8e-13 48.5 0.1 1.9e-11 44.3 0.0 2.6 3 0 0 3 3 3 1 Periplasmic binding protein DUF3460 PF11943.8 KEG05778.1 - 0.012 15.9 0.9 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3460) MFS_1 PF07690.16 KEG05780.1 - 4.3e-33 114.7 34.6 6.6e-24 84.5 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RR_TM4-6 PF06459.12 KEG05780.1 - 0.033 14.0 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RAB3GAP2_C PF14656.6 KEG05780.1 - 0.18 10.0 0.1 0.24 9.6 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MAJIN PF15077.6 KEG05780.1 - 0.47 10.2 2.1 0.66 9.7 2.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein PUF PF00806.19 KEG05781.1 - 8.5e-18 63.0 0.3 0.0039 16.8 0.0 5.2 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Peptidase_C58 PF03543.14 KEG05781.1 - 0.078 12.7 0.1 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen AAA PF00004.29 KEG05782.1 - 3.2e-45 153.8 0.0 7.6e-45 152.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG05782.1 - 1e-09 38.0 0.1 2.2e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KEG05782.1 - 1.6e-09 37.5 0.0 6.1e-09 35.7 0.0 2.1 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KEG05782.1 - 1.8e-09 37.7 0.0 5.3e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG05782.1 - 1.9e-07 31.6 0.1 2.8e-05 24.5 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEG05782.1 - 6.2e-06 26.5 1.3 0.0073 16.6 0.0 3.3 2 1 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KEG05782.1 - 6.5e-06 26.4 0.1 1.8e-05 24.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KEG05782.1 - 0.00022 20.5 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KEG05782.1 - 0.00039 20.2 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KEG05782.1 - 0.00044 20.5 0.0 0.0008 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEG05782.1 - 0.00055 19.5 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KEG05782.1 - 0.00066 19.7 0.0 0.008 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KEG05782.1 - 0.0011 18.9 0.3 0.026 14.4 0.0 2.8 3 0 0 3 3 3 1 NTPase AAA_18 PF13238.6 KEG05782.1 - 0.0019 18.8 0.0 0.0039 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KEG05782.1 - 0.002 17.6 0.1 0.5 9.8 0.0 3.2 4 0 0 4 4 3 1 Bacterial TniB protein AAA_30 PF13604.6 KEG05782.1 - 0.0028 17.4 0.4 0.014 15.1 0.1 2.4 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 KEG05782.1 - 0.0031 17.4 0.3 0.072 13.0 0.0 3.0 3 1 1 4 4 4 1 NACHT domain TsaE PF02367.17 KEG05782.1 - 0.0055 16.7 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KEG05782.1 - 0.0068 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF465 PF04325.13 KEG05782.1 - 0.0079 16.2 4.2 0.019 15.0 4.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF465) TIP49 PF06068.13 KEG05782.1 - 0.012 14.8 0.0 0.027 13.7 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KEG05782.1 - 0.015 15.0 0.1 0.039 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KEG05782.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KEG05782.1 - 0.016 15.6 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 KEG05782.1 - 0.02 14.7 0.1 0.057 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEG05782.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEG05782.1 - 0.026 14.1 0.6 0.13 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 KEG05782.1 - 0.029 14.2 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEG05782.1 - 0.029 14.1 0.0 0.91 9.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KEG05782.1 - 0.046 13.6 0.1 0.74 9.7 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KEG05782.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEG05782.1 - 0.055 13.1 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KEG05782.1 - 0.075 13.4 1.4 0.11 12.8 0.0 2.0 3 0 0 3 3 1 0 AAA domain Bac_DnaA PF00308.18 KEG05782.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 KEG05782.1 - 0.1 12.0 0.9 0.86 8.9 0.0 2.6 3 0 0 3 3 3 0 KaiC Prot_ATP_OB_N PF17758.1 KEG05782.1 - 0.11 12.2 0.1 0.66 9.7 0.0 2.3 3 0 0 3 3 3 0 Proteasomal ATPase OB N-terminal domain EzrA PF06160.12 KEG05782.1 - 0.12 10.5 0.3 0.2 9.8 0.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ABC_tran PF00005.27 KEG05782.1 - 0.13 12.8 0.0 0.52 10.8 0.0 2.3 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 KEG05782.1 - 0.19 10.8 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LIM_bind PF01803.16 KEG05784.1 - 0.22 11.0 4.7 0.053 13.0 1.1 1.9 2 1 0 2 2 2 0 LIM-domain binding protein Mucin PF01456.17 KEG05784.1 - 0.73 9.8 35.5 0.029 14.4 5.1 3.7 2 1 1 3 3 3 0 Mucin-like glycoprotein Kinesin PF00225.23 KEG05785.1 - 5.4e-21 74.9 0.0 6.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG05785.1 - 1e-16 61.2 0.0 2.3e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Microtubule binding FOXO_KIX_bdg PF16675.5 KEG05785.1 - 0.0058 16.9 0.0 0.0099 16.2 0.0 1.3 1 0 0 1 1 1 1 KIX-binding domain of forkhead box O, CR2 AAA_30 PF13604.6 KEG05785.1 - 0.012 15.4 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEG05785.1 - 0.016 14.9 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEG05785.1 - 0.03 13.8 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KEG05785.1 - 0.031 14.3 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KEG05785.1 - 0.048 12.7 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KEG05785.1 - 0.078 12.4 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 KEG05785.1 - 0.12 12.8 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-patch PF01585.23 KEG05786.1 - 2.1e-11 43.5 2.5 4.1e-11 42.6 2.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KEG05786.1 - 0.0013 18.7 1.1 0.0013 18.7 1.1 2.4 2 1 0 2 2 2 1 G-patch domain DUF3537 PF12056.8 KEG05786.1 - 0.26 10.1 0.1 0.34 9.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Galactosyl_T PF01762.21 KEG05788.1 - 1.8e-07 31.2 0.1 0.00031 20.6 0.0 3.0 2 1 1 3 3 3 3 Galactosyltransferase Peripla_BP_6 PF13458.6 KEG05789.1 - 4.1e-09 36.6 0.0 7.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein VID27 PF08553.10 KEG05790.1 - 1.6e-17 63.6 0.0 4.3e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain Shisa PF13908.6 KEG05792.1 - 5.7e-06 26.7 8.7 0.0015 18.8 0.3 2.1 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KEG05792.1 - 0.0012 19.6 0.1 1.7 9.6 0.0 2.2 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 KEG05792.1 - 0.0039 17.2 0.6 2.5 8.2 0.0 2.2 2 0 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) DUF4448 PF14610.6 KEG05792.1 - 0.025 14.4 0.3 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) MAP17 PF15807.5 KEG05792.1 - 0.11 12.7 0.5 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF1218 PF06749.12 KEG05792.1 - 0.13 12.8 5.7 4.5 7.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CYYR1 PF10873.8 KEG05792.1 - 0.18 12.3 11.8 1.9 8.9 1.9 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Orthoreo_P10 PF07204.11 KEG05792.1 - 0.18 11.8 3.6 2.3 8.2 0.2 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 WBP-1 PF11669.8 KEG05792.1 - 0.21 12.2 11.9 2.5 8.8 2.2 2.2 1 1 0 2 2 2 0 WW domain-binding protein 1 TMEM52 PF14979.6 KEG05792.1 - 0.27 11.1 12.6 0.82 9.6 1.9 2.2 2 0 0 2 2 2 0 Transmembrane 52 Mucin PF01456.17 KEG05792.1 - 0.71 9.9 8.2 3.7 7.5 0.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RCR PF12273.8 KEG05792.1 - 1.3 9.7 5.3 33 5.2 0.0 3.1 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pdase_C33_assoc PF14756.6 KEG05792.1 - 2.5 8.0 10.3 6.2 6.7 1.6 2.2 2 0 0 2 2 2 0 Peptidase_C33-associated domain Prominin PF05478.11 KEG05792.1 - 9.7 4.0 15.2 0.87 7.5 2.6 2.0 2 0 0 2 2 2 0 Prominin Adeno_VII PF03228.14 KEG05794.1 - 4.9 7.8 8.8 3.1 8.4 0.3 2.9 3 0 0 3 3 3 0 Adenoviral core protein VII Mucin PF01456.17 KEG05795.1 - 5.6e-05 23.2 10.4 5.6e-05 23.2 10.4 2.8 2 1 0 2 2 2 1 Mucin-like glycoprotein Alanine_zipper PF11839.8 KEG05795.1 - 0.82 10.1 53.1 0.12 12.7 8.9 4.6 3 1 0 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein FliP PF00813.20 KEG05795.1 - 2 8.3 7.7 2.2 8.1 0.2 2.5 2 0 0 2 2 2 0 FliP family GARP PF16731.5 KEG05795.1 - 3.8 7.2 55.1 0.014 15.1 23.8 3.3 1 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma GTP_CH_N PF12471.8 KEG05796.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal CHB_HEX_C_1 PF13290.6 KEG05797.1 - 0.0085 16.1 2.1 0.025 14.6 2.1 1.8 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 KEG05797.1 - 0.087 13.0 0.3 0.23 11.7 0.3 1.7 1 0 0 1 1 1 0 Fn3 associated FSA_C PF10479.9 KEG05799.1 - 0.029 12.5 0.7 0.027 12.6 0.7 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 KEG05799.1 - 0.096 10.8 2.6 0.075 11.1 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PaRep2b PF07775.11 KEG05799.1 - 0.2 10.1 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 PaRep2b protein K_channel_TID PF07941.11 KEG05799.1 - 0.68 10.4 15.3 0.24 11.9 9.4 2.5 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Band_7 PF01145.25 KEG05800.1 - 1e-26 94.0 0.2 1e-26 94.0 0.2 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KEG05800.1 - 1.3e-08 34.7 0.1 4e-08 33.2 0.0 1.9 1 1 1 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 KEG05800.1 - 0.0014 18.4 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family AAA_14 PF13173.6 KEG05801.1 - 3.8e-05 23.7 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG05801.1 - 0.0027 18.1 0.0 0.0071 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KEG05801.1 - 0.0047 17.5 0.0 0.029 14.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF4201 PF13870.6 KEG05802.1 - 0.26 11.0 5.6 0.054 13.2 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HSP70 PF00012.20 KEG05803.1 - 1e-43 149.5 0.1 1.1e-43 149.4 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein Asp_decarbox PF02261.16 KEG05803.1 - 0.0048 16.8 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate decarboxylase CD34_antigen PF06365.12 KEG05805.1 - 0.0029 17.2 0.1 0.0044 16.6 0.1 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family EphA2_TM PF14575.6 KEG05805.1 - 0.011 16.6 0.0 0.03 15.2 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2371 PF10177.9 KEG05805.1 - 0.047 13.9 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Adeno_E3_CR2 PF02439.15 KEG05805.1 - 0.11 12.3 1.5 0.22 11.3 1.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PTP_tm PF18861.1 KEG05805.1 - 0.27 11.2 3.8 0.4 10.6 3.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Syndecan PF01034.20 KEG05805.1 - 0.41 10.6 1.8 0.65 9.9 1.8 1.3 1 0 0 1 1 1 0 Syndecan domain IQ PF00612.27 KEG05810.1 - 0.0026 17.4 0.3 0.0084 15.8 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif RskA PF10099.9 KEG05810.1 - 0.055 13.8 4.9 0.063 13.6 4.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Homeobox_KN PF05920.11 KEG05810.1 - 0.1 12.6 0.5 0.2 11.6 0.5 1.5 1 0 0 1 1 1 0 Homeobox KN domain KH_1 PF00013.29 KEG05811.1 - 1.4e-19 69.6 0.6 2.3e-07 30.6 0.1 3.6 4 0 0 4 4 4 3 KH domain SLS PF14611.6 KEG05811.1 - 0.001 18.9 0.1 0.02 14.7 0.0 2.3 2 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator PIN_3 PF13470.6 KEG05811.1 - 1.7 9.5 6.1 12 6.7 0.1 2.5 2 1 0 2 2 2 0 PIN domain TPH PF13868.6 KEG05812.1 - 3.3e-10 39.0 78.8 4e-10 38.7 78.8 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain CoA_binding_3 PF13727.6 KEG05812.1 - 0.67 10.0 5.6 0.17 11.9 1.1 2.2 1 1 2 3 3 3 0 CoA-binding domain Zip PF02535.22 KEG05813.1 - 0.0022 17.3 8.8 0.0024 17.1 8.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cys_rich_FGFR PF00839.17 KEG05813.1 - 0.027 14.6 1.4 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 Cysteine rich repeat CHCH PF06747.13 KEG05813.1 - 0.03 14.5 0.3 0.35 11.1 0.1 2.5 2 0 0 2 2 2 0 CHCH domain Connexin PF00029.19 KEG05813.1 - 0.039 13.7 0.4 0.049 13.4 0.4 1.1 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 KEG05813.1 - 0.06 11.3 3.3 0.077 10.9 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 KEG05813.1 - 0.06 13.0 0.7 0.089 12.5 0.7 1.3 1 0 0 1 1 1 0 FAM176 family FAM76 PF16046.5 KEG05813.1 - 0.063 12.6 4.4 0.076 12.4 4.4 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4834 PF16118.5 KEG05813.1 - 0.068 14.1 0.1 0.09 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 KEG05813.1 - 0.24 11.7 2.5 3 8.1 2.2 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 AF-4 PF05110.13 KEG05813.1 - 0.24 9.4 7.7 0.28 9.2 7.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Conotoxin PF02950.17 KEG05813.1 - 0.41 11.7 3.7 7.1 7.7 3.7 2.5 1 1 0 1 1 1 0 Conotoxin Macoilin PF09726.9 KEG05813.1 - 1.9 7.0 5.2 2 6.9 5.2 1.0 1 0 0 1 1 1 0 Macoilin family NicO PF03824.16 KEG05813.1 - 2.3 7.5 9.4 2.9 7.2 9.4 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SapB_1 PF05184.15 KEG05815.1 - 0.038 14.0 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Saposin-like type B, region 1 MarR_2 PF12802.7 KEG05815.1 - 0.074 12.9 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 MarR family SATase_N PF06426.14 KEG05815.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Dscam_C PF12355.8 KEG05815.1 - 1.4 9.9 4.6 9.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 KEG05815.1 - 2.2 7.7 5.0 1.1 8.7 0.5 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KEG05815.1 - 2.3 8.3 8.9 0.89 9.6 1.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MFS_1 PF07690.16 KEG05817.1 - 2e-06 27.0 12.6 0.00036 19.6 10.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily TMIE PF16038.5 KEG05820.1 - 0.0035 17.1 0.1 0.0051 16.6 0.1 1.3 1 0 0 1 1 1 1 TMIE protein DUF4713 PF15831.5 KEG05820.1 - 5.7 7.5 9.3 8.5 6.9 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) EBP PF05241.12 KEG05822.1 - 2.4e-23 82.5 2.6 3.3e-23 82.1 2.6 1.2 1 0 0 1 1 1 1 Emopamil binding protein ASC PF00858.24 KEG05822.1 - 0.26 10.2 0.3 0.35 9.8 0.3 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Abhydrolase_9_N PF15420.6 KEG05822.1 - 4.1 7.3 12.8 0.51 10.3 3.8 2.1 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Trm112p PF03966.16 KEG05824.1 - 3.3e-10 40.4 0.0 4.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_SprT PF17283.2 KEG05824.1 - 0.77 9.7 6.4 4.9 7.2 0.6 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Guanylate_cyc PF00211.20 KEG05828.1 - 1.5e-19 70.3 0.1 1.8e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain 30K_MP_C_Ter PF11330.8 KEG05829.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.0 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins PIF1 PF05970.14 KEG05832.1 - 1.1e-20 74.2 1.0 6.2e-11 42.1 0.1 3.1 3 0 0 3 3 3 2 PIF1-like helicase Herpes_Helicase PF02689.14 KEG05832.1 - 0.00024 19.2 0.0 0.00035 18.7 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KEG05832.1 - 0.00042 20.1 0.2 0.0012 18.6 0.2 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KEG05832.1 - 0.02 14.6 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SH3_13 PF18335.1 KEG05832.1 - 0.059 13.2 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain LRR_6 PF13516.6 KEG05834.1 - 9.2e-05 22.2 0.0 5.2 7.4 0.0 3.9 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KEG05834.1 - 0.00022 21.5 0.0 0.88 10.1 0.0 3.1 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG05834.1 - 0.00052 19.7 0.1 0.031 14.0 0.0 2.9 1 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 KEG05835.1 - 1.1e-08 35.2 0.0 0.013 15.9 0.0 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG05835.1 - 2.6e-05 23.9 0.0 0.17 11.7 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KEG05835.1 - 0.00037 20.3 0.0 6.8 7.0 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KEG05835.1 - 0.096 13.3 1.4 64 4.7 0.0 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat Semialdhyde_dhC PF02774.18 KEG05837.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain HR1 PF02185.16 KEG05838.1 - 0.19 11.9 3.7 0.44 10.7 3.7 1.6 1 1 0 1 1 1 0 Hr1 repeat Alanine_zipper PF11839.8 KEG05840.1 - 0.32 11.4 80.7 0.16 12.4 5.6 4.9 3 2 2 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein GARP PF16731.5 KEG05840.1 - 0.95 9.1 68.9 0.03 14.0 17.6 4.3 2 1 3 5 5 5 0 Glutamic acid/alanine-rich protein of Trypanosoma Complex1_51K PF01512.17 KEG05842.1 - 7.6e-45 152.5 0.0 1.2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KEG05842.1 - 5.7e-28 96.8 0.1 1.6e-27 95.4 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KEG05842.1 - 3.3e-08 33.3 0.0 8.2e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 SLBB domain DUF780 PF05611.11 KEG05842.1 - 0.028 15.2 0.6 0.063 14.1 0.6 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) Pkinase PF00069.25 KEG05844.1 - 2.6e-22 79.5 0.0 3.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG05844.1 - 2.9e-13 49.7 0.0 4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG05844.1 - 7.4e-10 38.2 0.1 1e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG05844.1 - 5.6e-06 26.4 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEG05844.1 - 0.0041 16.5 0.1 0.0077 15.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEG05844.1 - 0.09 12.1 0.0 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RHSP PF07999.11 KEG05847.1 - 1e-95 321.2 1.5 2.7e-76 257.2 0.0 3.3 1 1 1 2 2 2 2 Retrotransposon hot spot protein Macro_2 PF14519.6 KEG05847.1 - 0.004 16.5 0.0 0.049 13.0 0.0 2.1 2 0 0 2 2 2 1 Macro-like domain UPF0261 PF06792.11 KEG05847.1 - 0.23 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) WSD PF15613.6 KEG05847.1 - 1.6 9.3 5.8 0.57 10.7 0.6 2.6 2 1 1 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif HTH_17 PF12728.7 KEG05847.1 - 2 8.7 5.7 19 5.5 0.5 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain Fructosamin_kin PF03881.14 KEG05848.1 - 1.4e-27 96.7 0.3 1.4e-27 96.7 0.3 1.0 1 0 0 1 1 1 1 Fructosamine kinase Peptidase_M8 PF01457.16 KEG05849.1 - 3.9e-23 82.0 0.0 4.7e-21 75.1 0.0 2.1 1 1 0 1 1 1 1 Leishmanolysin Mucin PF01456.17 KEG05849.1 - 0.0028 17.7 0.1 0.0042 17.1 0.1 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Peptidase_M8 PF01457.16 KEG05850.1 - 2.3e-18 66.2 0.0 2.9e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Phage_holin_7_1 PF16081.5 KEG05851.1 - 0.0099 16.1 0.3 0.013 15.7 0.3 1.1 1 0 0 1 1 1 1 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Med30 PF11315.8 KEG05853.1 - 0.057 13.6 5.6 0.18 12.0 5.4 1.9 1 1 0 1 1 1 0 Mediator complex subunit 30 YabA PF06156.13 KEG05853.1 - 4.5 8.0 6.8 25 5.6 1.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA STAT_alpha PF01017.20 KEG05853.1 - 9.3 6.1 9.1 1.8 8.4 1.5 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain PPR_2 PF13041.6 KEG05854.1 - 7.2e-05 22.9 0.0 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 KEG05854.1 - 0.049 13.7 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Galactosyl_T PF01762.21 KEG05856.1 - 5.2e-05 23.1 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 1 Galactosyltransferase APA3_viroporin PF11289.8 KEG05859.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Coronavirus accessory protein 3a DUF1117 PF06547.12 KEG05859.1 - 0.013 16.0 0.5 0.025 15.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Mucin PF01456.17 KEG05860.1 - 0.0022 18.0 20.9 0.52 10.3 0.3 3.2 2 2 0 2 2 2 2 Mucin-like glycoprotein Tai4 PF16695.5 KEG05860.1 - 0.25 11.9 4.2 0.25 11.9 0.1 2.9 2 1 1 3 3 3 0 Type VI secretion system (T6SS), amidase immunity protein PaaB PF06243.11 KEG05860.1 - 0.3 11.3 1.4 0.84 9.9 0.4 2.1 2 0 0 2 2 2 0 Phenylacetic acid degradation B ATP-synt_D PF01813.17 KEG05860.1 - 0.96 9.2 8.0 0.11 12.4 1.5 2.5 1 1 1 2 2 2 0 ATP synthase subunit D MCU PF04678.13 KEG05860.1 - 2.3 8.3 4.9 1.2 9.2 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Exonuc_VII_S PF02609.16 KEG05860.1 - 2.4 8.3 8.2 2.1 8.4 0.9 3.0 2 0 0 2 2 2 0 Exonuclease VII small subunit Glyco_trans_1_2 PF13524.6 KEG05861.1 - 1.8 9.0 6.6 45 4.5 0.1 3.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 IMS_C PF11799.8 KEG05863.1 - 1.4e-08 35.4 0.0 2.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cwf_Cwc_15 PF04889.12 KEG05863.1 - 0.0028 17.4 3.6 0.0043 16.8 3.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CLZ PF16526.5 KEG05864.1 - 0.009 16.3 0.8 0.009 16.3 0.8 2.9 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jnk-SapK_ap_N PF09744.9 KEG05864.1 - 2.6 8.2 22.6 0.053 13.8 0.9 3.0 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KEG05864.1 - 4.2 7.4 6.2 2.5 8.2 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) PTP_tm PF18861.1 KEG05868.1 - 0.00015 21.8 0.3 0.0003 20.8 0.3 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD99L2 PF12301.8 KEG05868.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 CD34_antigen PF06365.12 KEG05868.1 - 0.036 13.7 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Syndecan PF01034.20 KEG05868.1 - 0.42 10.6 1.5 0.96 9.4 1.5 1.5 1 0 0 1 1 1 0 Syndecan domain NS3_envE PF02723.14 KEG05869.1 - 0.004 17.2 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 Non-structural protein NS3/Small envelope protein E Extensin_2 PF04554.13 KEG05869.1 - 2.4 8.3 6.7 0.29 11.2 2.3 1.7 2 0 0 2 2 2 0 Extensin-like region EphA2_TM PF14575.6 KEG05870.1 - 0.024 15.5 0.0 0.053 14.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PMP1_2 PF08114.11 KEG05870.1 - 0.11 12.3 0.7 0.23 11.3 0.7 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Rax2 PF12768.7 KEG05870.1 - 0.11 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2203 PF09969.9 KEG05870.1 - 0.13 13.0 0.0 0.35 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Glycophorin_A PF01102.18 KEG05870.1 - 0.16 12.2 0.1 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Glycophorin A Pex14_N PF04695.13 KEG05871.1 - 1.6 9.3 9.0 1.2 9.7 1.5 2.2 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Metallophos PF00149.28 KEG05872.1 - 1.2e-34 120.7 0.3 1.5e-34 120.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SelR PF01641.18 KEG05873.1 - 4.8e-23 81.5 0.1 5.2e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 SelR domain SelR PF01641.18 KEG05874.1 - 2.7e-12 46.8 0.0 6e-12 45.7 0.0 1.5 2 0 0 2 2 2 1 SelR domain TF_Zn_Ribbon PF08271.12 KEG05874.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PsiF_repeat PF07769.14 KEG05874.1 - 0.072 13.0 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 psiF repeat GSK-3_bind PF05350.12 KEG05878.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding DXP_reductoisom PF02670.16 KEG05879.1 - 0.026 15.2 0.0 0.032 15.0 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase zf-B_box PF00643.24 KEG05881.1 - 2.2e-15 56.5 23.8 9.8e-09 35.2 3.8 2.8 3 0 0 3 3 3 2 B-box zinc finger DUF2321 PF10083.9 KEG05881.1 - 1.5 8.4 8.1 1.3 8.6 4.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Thioredoxin PF00085.20 KEG05882.1 - 1.5e-06 28.1 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KEG05882.1 - 0.00029 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KEG05882.1 - 0.027 14.8 0.1 0.33 11.3 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like DUF953 PF06110.11 KEG05882.1 - 0.034 13.8 0.2 0.11 12.2 0.2 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 KEG05882.1 - 0.071 13.6 0.1 0.4 11.2 0.1 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain Metallophos PF00149.28 KEG05883.1 - 6.1e-08 33.4 0.0 9.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEG05883.1 - 0.0016 18.7 0.0 0.085 13.0 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UCR_hinge PF02320.16 KEG05887.1 - 2.3e-17 63.0 5.1 2.5e-17 62.8 5.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CX9C PF16860.5 KEG05887.1 - 0.1 12.6 3.9 0.23 11.5 3.9 1.7 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, EF-hand_6 PF13405.6 KEG05889.1 - 1.2e-05 24.9 1.0 0.00032 20.4 0.2 3.0 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KEG05889.1 - 1.7e-05 25.1 2.1 0.00013 22.3 0.7 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KEG05889.1 - 0.00018 21.3 3.6 0.045 13.6 1.7 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG05889.1 - 0.00083 18.7 0.2 0.00083 18.7 0.2 3.3 4 0 0 4 4 4 1 EF hand DUF1456 PF07308.13 KEG05889.1 - 0.0076 16.6 1.5 1.4 9.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) HNHc_6 PF16784.5 KEG05889.1 - 0.028 14.0 0.3 0.041 13.4 0.2 1.4 1 1 0 1 1 1 0 Putative HNHc nuclease Styelin PF17562.2 KEG05889.1 - 8 6.9 7.5 0.37 11.2 1.2 2.0 2 0 0 2 2 2 0 Styelin Gag_p12 PF01141.18 KEG05890.1 - 6.1 7.3 22.0 4.9 7.6 0.6 4.9 2 2 4 6 6 6 0 Gag polyprotein, inner coat protein p12 Peripla_BP_6 PF13458.6 KEG05894.1 - 7e-06 25.9 6.2 0.0037 17.0 0.2 2.7 2 1 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG05894.1 - 0.00084 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NAD_binding_1 PF00175.21 KEG05895.1 - 1.1e-19 71.1 0.0 1.5e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG05895.1 - 3.4e-09 36.9 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEG05895.1 - 3.2e-07 30.6 0.0 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_2 PF00890.24 KEG05896.1 - 3.2e-07 29.8 4.5 4.3e-07 29.4 4.5 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEG05896.1 - 3.2e-06 26.8 3.4 4e-06 26.4 3.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEG05896.1 - 4.4e-06 26.0 2.6 5.7e-06 25.7 2.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KEG05896.1 - 1.8e-05 24.1 0.3 2.1e-05 23.9 0.3 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KEG05896.1 - 3.5e-05 23.2 0.8 4.3e-05 22.9 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEG05896.1 - 0.00031 19.6 1.0 0.00038 19.3 1.0 1.1 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KEG05896.1 - 0.002 17.8 1.8 0.0029 17.3 1.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEG05896.1 - 0.0046 16.3 0.8 0.0061 15.9 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEG05896.1 - 0.0075 16.5 0.7 0.013 15.7 0.7 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEG05896.1 - 0.018 15.6 1.5 0.033 14.8 1.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG05896.1 - 0.13 11.5 1.9 0.18 11.0 1.9 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEG05896.1 - 0.26 10.3 1.6 0.99 8.4 1.9 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Aldo_ket_red PF00248.21 KEG05898.1 - 5.8e-33 114.4 0.0 3.6e-31 108.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sporozoite_P67 PF05642.11 KEG05900.1 - 0.079 11.0 4.1 0.084 11.0 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 KEG05902.1 - 4e-05 23.6 2.4 5.6e-05 23.2 2.4 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4033 PF13225.6 KEG05902.1 - 0.052 13.5 0.2 0.073 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) His_binding PF02098.16 KEG05903.1 - 0.36 10.9 3.3 0.43 10.6 1.0 2.2 1 1 1 2 2 2 0 Tick histamine binding protein Apo-CII PF05355.11 KEG05903.1 - 4.7 7.4 6.8 32 4.8 0.3 2.8 1 1 1 2 2 2 0 Apolipoprotein C-II RNase_H PF00075.24 KEG05904.1 - 7.5e-05 22.9 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KEG05906.1 - 8.3e-30 104.0 0.0 9.8e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KEG05907.1 - 0.02 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cellulase PF00150.18 KEG05910.1 - 0.21 11.0 0.0 0.47 9.8 0.0 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Aa_trans PF01490.18 KEG05911.1 - 3.6e-48 164.3 21.8 4.2e-48 164.1 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.22 KEG05912.1 - 0.00014 21.6 0.1 0.00027 20.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1 PF04857.20 KEG05913.1 - 5.6e-77 259.0 0.0 7e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease OmpH PF03938.14 KEG05913.1 - 0.064 13.6 4.3 0.11 12.8 4.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CSD PF00313.22 KEG05914.1 - 1.2e-12 47.5 0.0 2.3e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain EphA2_TM PF14575.6 KEG05916.1 - 0.0065 17.3 0.0 0.012 16.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 KEG05916.1 - 0.028 13.3 0.2 0.035 13.0 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Mito_fiss_reg PF05308.11 KEG05916.1 - 0.073 13.2 1.0 0.099 12.7 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator LAX PF15681.5 KEG05916.1 - 0.1 11.4 0.6 0.84 8.4 0.0 2.0 1 1 0 2 2 2 0 Lymphocyte activation family X CYYR1 PF10873.8 KEG05916.1 - 5.7 7.4 5.8 19 5.7 5.8 1.7 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 IlvB_leader PF08049.11 KEG05917.1 - 4.1 7.4 7.0 9.4 6.3 1.7 2.4 2 0 0 2 2 2 0 IlvB leader peptide Peripla_BP_6 PF13458.6 KEG05918.1 - 8.2e-05 22.4 3.4 0.059 13.0 0.9 3.0 2 1 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG05918.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Mucin PF01456.17 KEG05919.1 - 0.031 14.3 15.1 0.1 12.6 15.0 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein Cyclin PF08613.11 KEG05921.1 - 4.3e-16 59.7 0.2 6.5e-16 59.1 0.2 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEG05921.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain SUIM_assoc PF16619.5 KEG05922.1 - 0.33 11.0 6.0 0.27 11.3 2.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cast PF10174.9 KEG05925.1 - 0.0018 16.6 4.2 0.035 12.3 0.7 2.4 2 0 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone DUF2284 PF10050.9 KEG05925.1 - 1.3 8.7 11.4 2.4 7.9 6.7 2.4 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) DUF5320 PF17253.2 KEG05925.1 - 1.6 9.8 15.1 12 7.0 0.2 4.4 3 1 1 4 4 4 0 Family of unknown function (DUF5320) Exonuc_VII_L PF02601.15 KEG05925.1 - 2.3 7.7 19.1 0.046 13.3 1.6 3.0 2 1 0 2 2 2 0 Exonuclease VII, large subunit HMMR_N PF15905.5 KEG05925.1 - 2.5 7.5 15.0 0.19 11.1 1.9 3.2 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Kre28 PF17097.5 KEG05926.1 - 0.0058 15.6 19.1 0.16 10.9 1.3 5.6 5 1 1 6 6 6 2 Spindle pole body component RNase_J_C PF17770.1 KEG05926.1 - 0.95 10.6 4.1 1.7 9.7 0.5 3.2 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DUF3808 PF10300.9 KEG05929.1 - 2.6e-17 62.8 0.1 7.8e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KEG05929.1 - 0.048 13.9 1.0 10 6.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Carboxyl_trans PF01039.22 KEG05930.1 - 1.8e-125 419.4 0.0 2.2e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain End_tail_spike PF12219.8 KEG05930.1 - 0.17 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase EF-hand_1 PF00036.32 KEG05931.1 - 2.9e-41 136.0 11.4 5.6e-10 38.1 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KEG05931.1 - 1e-35 122.0 3.3 5.1e-18 65.3 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG05931.1 - 3.4e-31 106.9 10.9 1.1e-13 50.8 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KEG05931.1 - 3.7e-30 101.3 5.7 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEG05931.1 - 6.6e-26 88.6 8.5 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KEG05931.1 - 2.1e-16 60.0 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KEG05931.1 - 7.7e-09 35.4 0.7 0.00034 20.5 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KEG05931.1 - 3.5e-07 30.5 0.0 0.0077 16.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KEG05931.1 - 2.3e-06 28.4 0.0 0.00054 20.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 KEG05931.1 - 1.4e-05 25.0 0.5 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KEG05931.1 - 0.00013 22.0 1.1 0.00057 19.9 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 KEG05931.1 - 0.00037 20.5 0.4 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 KEG05931.1 - 0.0011 19.8 0.3 3.4 8.5 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 KEG05931.1 - 0.0012 18.8 0.7 0.37 10.7 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 KEG05931.1 - 0.0017 18.5 1.4 0.39 11.0 0.1 3.1 1 1 2 3 3 3 1 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 KEG05931.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 KEG05931.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) DUF1103 PF06513.11 KEG05931.1 - 0.0065 16.1 1.3 0.0076 15.9 1.3 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Poly_export PF02563.16 KEG05931.1 - 0.0093 16.2 0.1 0.77 10.0 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 KEG05931.1 - 0.012 15.7 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF5580 PF17743.1 KEG05931.1 - 0.013 14.1 0.0 0.013 14.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) dCache_2 PF08269.11 KEG05931.1 - 0.018 14.2 0.1 1.2 8.2 0.0 2.2 1 1 0 2 2 2 0 Cache domain SurA_N_2 PF13623.6 KEG05931.1 - 0.028 14.3 1.5 1.1 9.1 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 KEG05931.1 - 0.028 14.7 0.2 5.8 7.3 0.0 2.4 1 1 0 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 KEG05931.1 - 0.039 13.6 0.2 0.097 12.3 0.2 1.6 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 KEG05931.1 - 0.073 13.3 0.8 0.89 9.7 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein TetR_C_7 PF14246.6 KEG05931.1 - 0.14 12.2 0.1 11 6.0 0.0 2.6 1 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain NTP_transf_4 PF13562.6 KEG05938.1 - 0.083 13.1 0.0 0.097 12.9 0.0 1.1 1 0 0 1 1 1 0 Sugar nucleotidyl transferase HSP70 PF00012.20 KEG05940.1 - 4.8e-12 44.9 5.4 5.4e-12 44.7 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein CPL PF08144.11 KEG05940.1 - 0.031 14.6 0.1 0.044 14.1 0.1 1.2 1 0 0 1 1 1 0 CPL (NUC119) domain DUF1542 PF07564.11 KEG05940.1 - 0.033 14.3 3.8 0.78 9.9 2.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Wtap PF17098.5 KEG05940.1 - 0.036 14.0 0.7 0.044 13.7 0.7 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family SAPIS-gp6 PF16722.5 KEG05940.1 - 0.41 11.1 5.4 0.12 12.8 2.2 1.7 1 1 1 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus HSP70 PF00012.20 KEG05941.1 - 9.3e-164 545.9 0.5 1.1e-163 545.6 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEG05941.1 - 3.3e-12 45.9 0.0 7.5e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Asp_decarbox PF02261.16 KEG05941.1 - 0.052 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase CtnDOT_TraJ PF07863.11 KEG05942.1 - 0.66 10.7 3.3 0.83 10.3 1.0 2.0 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon RRM_1 PF00076.22 KEG05944.1 - 1.9e-21 75.7 0.0 3.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG05944.1 - 0.00059 19.4 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG05944.1 - 0.0072 16.2 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KEG05944.1 - 1.4 9.2 6.2 2.4 8.4 0.1 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Y_phosphatase PF00102.27 KEG05945.1 - 1.6e-65 220.9 0.0 2.3e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KEG05945.1 - 0.00055 20.0 0.2 0.0012 18.9 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KEG05945.1 - 0.0033 17.2 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KEG05945.1 - 0.12 12.5 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate Aa_trans PF01490.18 KEG05946.1 - 8.9e-55 186.0 31.0 1.1e-54 185.7 31.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG05946.1 - 5.4e-06 25.7 11.9 5.4e-06 25.7 11.9 2.3 1 1 0 2 2 2 2 Tryptophan/tyrosine permease family zf-CCCH PF00642.24 KEG05947.1 - 0.0012 18.7 3.9 0.0012 18.7 3.9 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG05947.1 - 0.012 16.3 3.9 0.12 13.0 0.3 2.4 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 KEG05947.1 - 1.4 9.1 11.7 0.093 12.8 5.7 2.1 2 0 0 2 2 2 0 Zinc finger domain YLP PF02757.17 KEG05948.1 - 0.062 13.3 0.7 0.2 11.7 0.7 1.9 1 0 0 1 1 1 0 YLP motif Peptidase_M8 PF01457.16 KEG05949.1 - 4.2e-58 197.3 16.1 2.1e-49 168.7 10.6 2.0 1 1 1 2 2 2 2 Leishmanolysin Peptidase_M8 PF01457.16 KEG05950.1 - 1.3e-45 156.1 0.0 1.7e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin YjgF_endoribonc PF14588.6 KEG05951.1 - 2.1e-34 118.8 0.6 2.6e-34 118.5 0.6 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 KEG05951.1 - 1.9e-23 82.8 0.2 2.8e-23 82.2 0.2 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP FTA4 PF13093.6 KEG05952.1 - 0.067 13.1 1.7 0.072 13.0 1.7 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Cwf_Cwc_15 PF04889.12 KEG05952.1 - 0.31 10.7 11.9 0.36 10.5 11.9 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KEG05952.1 - 0.48 9.7 8.4 0.52 9.6 8.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4807 PF16065.5 KEG05953.1 - 0.0035 17.0 0.2 0.0044 16.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) DUF1501 PF07394.12 KEG05953.1 - 0.068 12.2 0.1 0.07 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Peptidase_M13 PF01431.21 KEG05953.1 - 0.1 12.2 0.2 0.12 11.9 0.2 1.3 1 1 0 1 1 1 0 Peptidase family M13 DUF2612 PF11041.8 KEG05955.1 - 0.00071 19.5 0.0 0.00083 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2612) IDH PF03971.14 KEG05955.1 - 0.0097 14.4 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DUF4055 PF13264.6 KEG05955.1 - 0.02 15.0 1.2 0.028 14.6 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) YwqJ-deaminase PF14431.6 KEG05955.1 - 0.049 13.8 1.1 1.2 9.3 0.1 2.1 1 1 1 2 2 2 0 YwqJ-like deaminase DUF2312 PF10073.9 KEG05955.1 - 0.26 11.0 6.7 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Arm PF00514.23 KEG05956.1 - 3.4e-36 122.2 19.0 1.9e-07 30.9 0.0 8.9 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KEG05956.1 - 8e-20 69.2 5.8 9.1e-05 22.4 0.0 7.7 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 KEG05956.1 - 2e-17 63.3 14.5 4.3e-06 27.0 0.0 5.5 2 2 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.6 KEG05956.1 - 1.1e-15 57.7 15.8 0.0031 18.0 0.1 6.4 5 1 2 7 7 6 6 HEAT-like repeat Cnd1 PF12717.7 KEG05956.1 - 9.1e-14 51.8 0.1 0.0043 17.1 0.0 3.6 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KEG05956.1 - 3.4e-12 45.7 3.4 3.9e-06 25.7 0.6 3.4 2 1 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 KEG05956.1 - 3.1e-09 36.9 0.1 0.037 13.7 0.0 4.1 2 1 2 4 4 4 2 DNA alkylation repair enzyme CLASP_N PF12348.8 KEG05956.1 - 3.4e-06 26.8 0.4 0.11 12.1 0.1 2.9 1 1 1 2 2 2 2 CLASP N terminal CHASE6_C PF17150.4 KEG05956.1 - 5.3e-05 23.8 5.8 6.7 7.5 0.0 6.1 5 1 0 6 6 6 1 C-terminal domain of two-partite extracellular sensor domain V-ATPase_H_C PF11698.8 KEG05956.1 - 0.00032 20.8 0.2 0.09 12.9 0.1 3.5 3 2 0 3 3 3 1 V-ATPase subunit H Proteasom_PSMB PF10508.9 KEG05956.1 - 0.0023 16.5 1.9 0.058 11.9 0.3 2.5 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit Mo25 PF08569.11 KEG05956.1 - 0.0044 16.4 0.0 0.77 9.1 0.0 2.5 1 1 1 2 2 2 1 Mo25-like Atx10homo_assoc PF09759.9 KEG05956.1 - 0.0056 16.7 0.2 6.9 6.8 0.1 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_UF PF18817.1 KEG05956.1 - 0.015 15.6 0.8 1.8 8.9 0.0 4.1 4 1 1 5 5 5 0 Repeat of uncharacterized protein PH0542 Vac14_Fab1_bd PF12755.7 KEG05956.1 - 0.02 15.5 0.1 0.69 10.6 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Arm_2 PF04826.13 KEG05956.1 - 0.042 13.3 0.1 47 3.3 0.0 3.4 2 1 2 4 4 4 0 Armadillo-like AbiEi_1 PF09407.10 KEG05956.1 - 0.05 13.9 6.4 4.6 7.5 0.1 3.7 3 2 1 4 4 4 0 AbiEi antitoxin C-terminal domain HEAT_PBS PF03130.16 KEG05956.1 - 0.061 14.0 14.9 2.7 8.9 0.3 6.1 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat Nipped-B_C PF12830.7 KEG05956.1 - 0.085 12.8 0.3 0.62 10.0 0.0 2.5 2 1 1 3 3 3 0 Sister chromatid cohesion C-terminus API5 PF05918.11 KEG05956.1 - 0.59 8.9 2.6 30 3.3 0.3 3.4 2 2 3 5 5 5 0 Apoptosis inhibitory protein 5 (API5) Kinesin PF00225.23 KEG05958.1 - 3.5e-78 262.9 0.1 3.5e-78 262.9 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG05958.1 - 2e-23 83.0 0.0 4.8e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding ATPase PF06745.13 KEG05958.1 - 0.12 11.7 7.3 0.13 11.6 1.2 2.7 2 0 0 2 2 2 0 KaiC CDH1_2_SANT_HL1 PF18375.1 KEG05958.1 - 0.18 12.5 2.0 14 6.4 0.2 3.3 2 1 1 3 3 3 0 CDH1/2 SANT-Helical linker 1 CUTL PF16557.5 KEG05958.1 - 0.21 11.8 1.6 1.5 9.1 0.1 2.9 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB NDK PF00334.19 KEG05959.1 - 8.4e-13 48.5 0.0 3e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Mucin PF01456.17 KEG05960.1 - 0.00012 22.1 0.4 0.00012 22.1 0.4 2.7 2 1 0 2 2 2 1 Mucin-like glycoprotein LMBR1 PF04791.16 KEG05960.1 - 0.19 10.6 2.3 0.23 10.3 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KEG05960.1 - 0.38 10.9 2.7 0.84 9.8 2.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CSN7a_helixI PF18392.1 KEG05960.1 - 3.2 7.7 6.3 2.7 7.9 1.9 2.5 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Plasmid_RAQPRD PF09686.10 KEG05960.1 - 4 7.7 8.9 6.5 7.0 0.4 2.9 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF5082 PF16888.5 KEG05960.1 - 7.8 6.8 10.8 4.1 7.7 5.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Mucin PF01456.17 KEG05961.1 - 0.0015 18.6 1.3 0.0015 18.6 1.3 2.5 2 2 1 3 3 3 1 Mucin-like glycoprotein ISG65-75 PF11727.8 KEG05961.1 - 0.004 16.4 2.8 0.007 15.6 2.8 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein ABA_WDS PF02496.16 KEG05962.1 - 0.078 13.5 1.4 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 ABA/WDS induced protein SesA PF17107.5 KEG05963.1 - 1.3 9.2 20.3 0.14 12.3 2.9 3.2 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RisS_PPD PF16524.5 KEG05963.1 - 4.3 7.6 6.0 2.9 8.2 0.4 2.9 2 1 1 3 3 3 0 Periplasmic domain of Sensor histidine kinase RisS ELO PF01151.18 KEG05964.1 - 1.2e-43 149.4 16.4 2e-43 148.7 16.4 1.3 1 1 0 1 1 1 1 GNS1/SUR4 family AAA_7 PF12775.7 KEG05964.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region YABBY PF04690.13 KEG05965.1 - 3.8e-05 24.3 1.6 4.3e-05 24.1 1.6 1.2 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.10 KEG05965.1 - 0.0003 21.3 8.4 0.046 14.3 0.1 2.9 1 1 1 2 2 2 2 HMG-box domain DUF3106 PF11304.8 KEG05965.1 - 0.018 15.5 2.5 0.018 15.5 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) S1FA PF04689.13 KEG05965.1 - 0.34 11.1 0.1 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA HMG_box_2 PF09011.10 KEG05966.1 - 0.058 14.0 7.0 1.2 9.8 0.2 3.3 3 0 0 3 3 3 0 HMG-box domain Dopey_N PF04118.14 KEG05966.1 - 0.14 11.3 0.6 0.42 9.7 0.1 1.8 2 0 0 2 2 2 0 Dopey, N-terminal Iso_dh PF00180.20 KEG05967.1 - 4.3e-69 233.3 0.0 4.9e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HEAT PF02985.22 KEG05968.1 - 5.9e-20 69.7 15.5 0.00061 19.8 0.0 10.4 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 KEG05968.1 - 1.1e-13 51.4 4.9 0.028 14.8 0.0 6.8 3 2 4 7 7 7 5 HEAT repeats Cnd1 PF12717.7 KEG05968.1 - 0.005 16.9 1.3 2.4 8.2 0.0 3.8 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 KEG05970.1 - 1.1e-24 87.2 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG05970.1 - 5.3e-14 52.1 0.0 6.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG05970.1 - 3.3e-09 36.0 0.1 4.6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG05970.1 - 1.5e-06 28.3 0.0 0.00013 21.9 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG05970.1 - 0.0019 17.6 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M8 PF01457.16 KEG05971.1 - 1.3e-102 344.2 5.3 3e-55 187.9 2.2 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG05971.1 - 0.0063 16.7 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 KEG05971.1 - 0.064 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) HSP90 PF00183.18 KEG05972.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Hsp90 protein Peroxin-13_N PF04088.13 KEG05972.1 - 0.13 12.5 1.2 2 8.7 0.1 2.6 2 1 0 2 2 2 0 Peroxin 13, N-terminal region DinB_2 PF12867.7 KEG05972.1 - 0.13 12.7 0.8 2.4 8.7 0.2 2.7 2 0 0 2 2 2 0 DinB superfamily DUF3479 PF11965.8 KEG05972.1 - 1.9 8.6 8.6 0.24 11.5 1.5 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF3479) Serine_rich PF08824.10 KEG05972.1 - 2.5 8.1 6.3 3 7.8 0.2 3.0 1 1 0 2 2 2 0 Serine rich protein interaction domain Transposase_mut PF00872.18 KEG05973.1 - 0.051 12.4 0.1 0.076 11.9 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family SOG2 PF10428.9 KEG05973.1 - 0.087 12.0 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Creb_binding PF09030.10 KEG05973.1 - 0.21 12.3 4.2 0.8 10.4 1.0 2.4 2 0 0 2 2 2 0 Creb binding UvrB PF12344.8 KEG05974.1 - 0.075 12.9 1.0 0.21 11.5 1.0 1.7 1 0 0 1 1 1 0 Ultra-violet resistance protein B PFU PF09070.11 KEG05974.1 - 0.1 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) SSP160 PF06933.11 KEG05974.1 - 0.36 9.0 3.7 0.45 8.7 3.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 KEG05974.1 - 0.68 7.8 3.7 0.88 7.5 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.22 KEG05975.1 - 2.1e-52 177.0 0.0 2.5e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG05975.1 - 2.1e-34 118.3 0.0 2.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG05975.1 - 1.1e-10 41.3 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEG05975.1 - 7.6e-07 29.2 0.1 0.00021 21.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KEG05975.1 - 2.1e-05 24.6 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG05975.1 - 0.00017 22.0 0.1 0.00029 21.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEG05975.1 - 0.00026 21.0 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEG05975.1 - 0.00078 19.7 0.0 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KEG05975.1 - 0.002 17.6 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KEG05975.1 - 0.0043 17.6 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SRPRB PF09439.10 KEG05975.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KEG05975.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region KAP_NTPase PF07693.14 KEG05975.1 - 0.0098 15.2 0.1 0.015 14.5 0.1 1.4 1 1 0 1 1 1 1 KAP family P-loop domain FeoB_N PF02421.18 KEG05975.1 - 0.014 14.9 0.0 0.3 10.6 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KEG05975.1 - 0.019 15.5 0.0 0.084 13.4 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEG05975.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KEG05975.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEG05975.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 KEG05975.1 - 0.058 12.8 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KEG05975.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEG05975.1 - 0.065 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KEG05975.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KEG05975.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KEG05975.1 - 0.15 11.2 0.1 2.9 7.0 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 KEG05975.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.7 2 1 0 2 2 2 0 NTPase Septin PF00735.18 KEG05975.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Septin Sec3_C PF09763.9 KEG05976.1 - 2.7e-48 164.9 0.0 3.9e-48 164.4 0.0 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec3 Dmrt1 PF12374.8 KEG05977.1 - 3.6 8.1 8.7 2.4 8.7 3.9 2.5 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Ctr PF04145.15 KEG05979.1 - 0.031 14.9 0.0 0.031 14.9 0.0 2.3 3 1 1 4 4 4 0 Ctr copper transporter family Phage_Gp23 PF10669.9 KEG05979.1 - 0.072 13.4 0.5 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) TssO PF17561.2 KEG05979.1 - 2.9 8.0 5.1 2.7 8.1 0.9 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO YdfA_immunity PF12127.8 KEG05980.1 - 0.13 11.3 0.1 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 SigmaW regulon antibacterial CLP1_P PF16575.5 KEG05982.1 - 0.0053 16.6 0.1 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop HicB_lk_antitox PF15919.5 KEG05982.1 - 0.14 12.3 1.3 0.36 10.9 0.4 1.9 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Mucin PF01456.17 KEG05983.1 - 0.0033 17.4 2.4 0.0057 16.7 0.3 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein Alanine_zipper PF11839.8 KEG05983.1 - 7.9 6.9 16.0 3.7 8.0 5.2 2.2 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein EF-hand_1 PF00036.32 KEG05987.1 - 4.1e-15 54.1 0.2 8.8e-06 24.9 0.0 4.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KEG05987.1 - 8.2e-15 53.4 0.1 1.8e-05 24.3 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KEG05987.1 - 7.2e-14 52.0 0.3 1.3e-06 28.8 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG05987.1 - 3.2e-07 30.1 2.1 0.042 13.7 0.4 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KEG05987.1 - 2.6e-05 23.5 2.2 0.0013 18.2 0.0 3.2 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 KEG05987.1 - 2.8e-05 24.4 0.2 0.00055 20.2 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain Acyl-CoA_dh_N PF02771.16 KEG05988.1 - 6.9e-25 87.9 0.1 1e-24 87.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 KEG05988.1 - 0.036 14.6 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal UCR_14kD PF02271.16 KEG05989.1 - 0.086 12.8 0.6 0.17 11.9 0.5 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Guanylate_cyc PF00211.20 KEG05990.1 - 0.004 16.8 0.0 0.0077 15.9 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 KEG05991.1 - 5.1e-09 36.2 0.6 1.3e-05 25.1 0.1 2.9 2 1 1 3 3 3 3 Periplasmic binding protein Ribonuc_L-PSP PF01042.21 KEG05991.1 - 0.0082 16.1 0.0 0.15 12.0 0.0 2.6 3 0 0 3 3 3 1 Endoribonuclease L-PSP DUF327 PF03885.13 KEG05991.1 - 0.21 11.6 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Thymidylat_synt PF00303.19 KEG05994.1 - 7.3e-106 353.2 0.0 9.2e-106 352.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 KEG05994.1 - 3.7e-24 85.2 0.0 5.5e-23 81.4 0.0 2.6 1 1 0 1 1 1 1 Dihydrofolate reductase Nucleoside_tran PF01733.18 KEG05995.1 - 1.4e-30 106.7 0.6 1.4e-30 106.7 0.6 1.6 2 0 0 2 2 2 1 Nucleoside transporter Collectrin PF16959.5 KEG05995.1 - 0.088 12.6 1.6 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Renal amino acid transporter Rhodanese PF00581.20 KEG05996.1 - 9.2e-18 64.7 0.0 7.7e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF1930 PF09122.10 KEG05996.1 - 6e-10 39.0 0.2 1.2e-09 38.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Troponin PF00992.20 KEG05998.1 - 0.0058 16.9 10.5 0.1 12.9 4.2 2.6 1 1 1 2 2 2 2 Troponin DUF3829 PF12889.7 KEG05998.1 - 0.099 12.1 0.4 0.16 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2046 PF09755.9 KEG05998.1 - 0.1 11.8 7.9 0.24 10.6 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Snapin_Pallidin PF14712.6 KEG05998.1 - 0.12 12.8 7.8 0.17 12.3 0.8 3.2 1 1 1 3 3 3 0 Snapin/Pallidin FAM184 PF15665.5 KEG05998.1 - 0.2 11.4 15.1 0.38 10.5 15.1 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B LPP PF04728.13 KEG05998.1 - 0.28 11.6 10.7 1.1 9.8 0.4 4.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 KEG05998.1 - 0.29 11.3 6.2 0.51 10.5 4.9 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KEG05998.1 - 0.81 9.7 6.2 1.6 8.8 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 KEG05998.1 - 1 9.9 10.6 0.36 11.3 2.0 2.6 1 1 1 2 2 2 0 Spectrin repeat Seryl_tRNA_N PF02403.22 KEG05998.1 - 6 7.2 6.8 9.7 6.5 0.5 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CCDC144C PF14915.6 KEG05998.1 - 9.9 5.2 16.1 6.8 5.7 13.5 1.8 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region ADK PF00406.22 KEG06002.1 - 6.9e-47 159.3 0.0 4.9e-44 150.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KEG06002.1 - 7.9e-28 97.6 0.0 6.5e-25 88.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEG06002.1 - 5e-13 49.7 0.1 4.8e-09 36.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KEG06002.1 - 2.5e-10 40.7 0.0 6.2e-07 29.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KEG06002.1 - 2.4e-05 23.7 0.0 0.033 13.4 0.0 2.8 2 1 0 2 2 2 2 Zeta toxin Thymidylate_kin PF02223.17 KEG06002.1 - 7.6e-05 22.5 0.3 0.45 10.2 0.0 3.0 3 0 0 3 3 3 2 Thymidylate kinase Cytidylate_kin PF02224.18 KEG06002.1 - 0.00014 21.7 0.1 0.002 17.9 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 KEG06002.1 - 0.0023 18.4 0.0 0.18 12.2 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEG06002.1 - 0.0033 17.2 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 KEG06002.1 - 0.0038 16.6 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Hydin_ADK PF17213.3 KEG06002.1 - 0.0069 16.7 0.3 0.27 11.5 0.0 2.8 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 KEG06002.1 - 0.007 16.8 0.0 4.6 7.6 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KEG06002.1 - 0.0074 15.4 0.1 2.9 6.9 0.0 2.6 2 1 0 3 3 3 1 Type II/IV secretion system protein AAA_28 PF13521.6 KEG06002.1 - 0.016 15.5 0.2 2.1 8.5 0.4 3.2 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEG06002.1 - 0.021 14.7 0.0 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 NTPase ADK_lid PF05191.14 KEG06002.1 - 0.032 14.2 0.1 0.087 12.8 0.1 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid AAA_22 PF13401.6 KEG06002.1 - 0.032 14.5 0.6 7.9 6.8 0.0 3.3 4 1 0 4 4 3 0 AAA domain AbfS_sensor PF18225.1 KEG06002.1 - 0.032 14.1 0.9 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain AAA_19 PF13245.6 KEG06002.1 - 0.059 13.7 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEG06002.1 - 0.06 13.1 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 KEG06002.1 - 0.072 12.9 0.1 19 5.0 0.0 3.3 4 0 0 4 4 4 0 Deoxynucleoside kinase Rad17 PF03215.15 KEG06002.1 - 0.074 13.0 0.2 2.6 7.9 0.0 2.2 1 1 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KEG06002.1 - 0.15 11.4 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 KEG06002.1 - 0.16 11.4 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF5582 PF17819.1 KEG06002.1 - 0.18 12.2 0.1 22 5.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5582) AAA_24 PF13479.6 KEG06002.1 - 0.19 11.5 0.1 20 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mucin PF01456.17 KEG06003.1 - 0.014 15.4 1.2 0.017 15.1 1.2 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein HTH_Tnp_Mu_2 PF09039.11 KEG06004.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain RRXRR PF14239.6 KEG06004.1 - 0.16 11.8 2.9 11 5.9 0.5 2.5 2 0 0 2 2 2 0 RRXRR protein DUF3584 PF12128.8 KEG06005.1 - 0.0016 16.1 30.1 0.0018 15.9 30.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PspB PF06667.12 KEG06005.1 - 0.029 14.4 1.6 0.029 14.4 1.6 2.7 2 1 1 3 3 3 0 Phage shock protein B SLATT_6 PF18169.1 KEG06005.1 - 4.8 6.8 6.7 18 4.9 0.3 2.8 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 STPPase_N PF16891.5 KEG06008.1 - 1.8e-12 47.5 0.7 2.3e-12 47.2 0.7 1.2 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PAH PF02671.21 KEG06008.1 - 0.23 11.6 0.3 0.63 10.2 0.1 1.8 2 1 0 2 2 2 0 Paired amphipathic helix repeat SlyX PF04102.12 KEG06010.1 - 5.2 7.7 7.0 0.95 10.1 1.5 2.4 2 0 0 2 2 2 0 SlyX Sec23_trunk PF04811.15 KEG06012.1 - 3.6e-43 147.9 0.0 5.2e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEG06012.1 - 1e-20 73.4 1.3 1.2e-20 73.2 0.4 1.6 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KEG06012.1 - 3.5e-19 69.3 0.0 6.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KEG06012.1 - 0.0031 17.5 0.1 0.0073 16.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KEG06012.1 - 0.021 14.2 0.5 0.044 13.2 0.5 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 KEG06012.1 - 0.045 14.4 0.1 1.1 9.9 0.0 2.9 4 0 0 4 4 4 0 von Willebrand factor type A domain BNR_3 PF13859.6 KEG06015.1 - 1.3e-79 267.7 0.0 2.5e-79 266.8 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.6 KEG06015.1 - 8.5e-19 67.9 0.0 1.9e-15 56.9 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain Laminin_G_3 PF13385.6 KEG06015.1 - 0.0004 20.6 0.2 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily BNR PF02012.20 KEG06015.1 - 0.0025 17.5 12.9 0.33 11.1 0.2 4.8 4 0 0 4 4 4 2 BNR/Asp-box repeat CyRPA PF18638.1 KEG06015.1 - 0.013 14.6 0.2 1.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Cysteine-Rich Protective Antigen 6 bladed domain Sortilin-Vps10 PF15902.5 KEG06015.1 - 0.031 13.1 0.1 0.53 9.0 0.0 2.3 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, Sialidase PF02973.16 KEG06015.1 - 0.14 11.7 0.1 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 Sialidase, N-terminal domain DUF4185 PF13810.6 KEG06015.1 - 0.2 10.9 4.4 3.9 6.6 0.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4185) Utp8 PF10395.9 KEG06015.1 - 0.25 9.8 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Utp8 family RCDG1 PF15725.5 KEG06017.1 - 0.0034 17.8 1.4 0.0042 17.5 1.4 1.1 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein PRIMA1 PF16101.5 KEG06017.1 - 0.79 9.8 4.8 0.82 9.7 4.8 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KEG06017.1 - 2.3 7.6 4.4 2.4 7.6 4.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AhpC-TSA PF00578.21 KEG06018.1 - 3.5e-36 123.9 0.0 5e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEG06018.1 - 6.6e-16 58.3 0.0 7.9e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KEG06018.1 - 1.3e-13 50.6 0.0 2.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KEG06018.1 - 0.044 13.7 0.3 0.17 11.8 0.2 1.9 3 0 0 3 3 3 0 SCO1/SenC Mce4_CUP1 PF11887.8 KEG06021.1 - 0.0015 18.0 1.0 0.0056 16.2 0.5 2.0 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative Vps51 PF08700.11 KEG06021.1 - 0.0043 17.1 0.9 2.2 8.4 0.0 3.6 3 0 0 3 3 3 1 Vps51/Vps67 BLOC1_2 PF10046.9 KEG06021.1 - 0.008 16.5 7.3 0.64 10.4 0.7 3.7 1 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 KEG06021.1 - 0.04 13.5 21.2 0.15 11.6 7.8 3.5 1 1 2 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.11 KEG06021.1 - 0.068 13.6 1.5 11 6.5 0.1 3.9 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 KEG06021.1 - 0.081 11.9 10.5 0.82 8.6 7.7 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KEG06021.1 - 0.09 11.6 19.8 0.12 11.2 3.0 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FlgN PF05130.12 KEG06021.1 - 0.1 13.1 17.4 0.093 13.2 4.7 3.1 1 1 2 3 3 3 0 FlgN protein DUF1664 PF07889.12 KEG06021.1 - 0.2 11.7 18.7 5.7 7.0 1.2 4.3 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 KEG06021.1 - 0.25 11.3 11.6 0.098 12.6 3.9 3.6 3 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 KEG06021.1 - 0.37 10.8 9.9 0.58 10.2 0.6 3.3 1 1 2 3 3 3 0 Laminin Domain II IMD PF08397.11 KEG06021.1 - 0.48 9.8 14.9 0.12 11.8 7.9 2.7 1 1 1 2 2 2 0 IRSp53/MIM homology domain CENP-F_leu_zip PF10473.9 KEG06021.1 - 0.72 9.9 23.4 0.68 10.0 3.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T2SSF PF00482.23 KEG06021.1 - 0.73 9.8 6.6 3 7.8 1.2 3.0 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein F RmuC PF02646.16 KEG06021.1 - 0.75 8.9 12.9 2.8 7.0 0.8 3.1 2 1 0 3 3 3 0 RmuC family DUF948 PF06103.11 KEG06021.1 - 1.1 9.6 6.9 26 5.2 0.3 3.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 KEG06021.1 - 1.4 7.4 14.1 2 6.8 7.3 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 KEG06021.1 - 1.7 8.1 15.3 2.2 7.8 6.3 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit SKA2 PF16740.5 KEG06021.1 - 1.9 8.3 14.8 3 7.7 0.1 3.7 1 1 3 4 4 4 0 Spindle and kinetochore-associated protein 2 CdvA PF18822.1 KEG06021.1 - 2 8.2 13.3 0.51 10.2 1.0 4.1 1 1 2 4 4 4 0 CdvA-like coiled-coil domain MutS_IV PF05190.18 KEG06021.1 - 2.7 8.4 6.7 2.4 8.6 0.3 3.6 4 2 0 4 4 3 0 MutS family domain IV Dna2 PF08696.11 KEG06021.1 - 3.2 7.5 6.6 2.5 7.8 0.8 2.7 2 1 1 3 3 3 0 DNA replication factor Dna2 TMPIT PF07851.13 KEG06021.1 - 4.3 6.5 12.2 4.1 6.6 2.5 2.9 1 1 1 3 3 3 0 TMPIT-like protein Lectin_N PF03954.14 KEG06021.1 - 4.6 7.0 6.2 6.7 6.5 0.4 2.8 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain RNase_H PF00075.24 KEG06024.1 - 1e-07 32.3 0.0 2e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 RNase H OTT_1508_deam PF14441.6 KEG06025.1 - 0.089 12.8 3.2 0.14 12.2 3.2 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase DUF5402 PF17393.2 KEG06029.1 - 0.0062 16.5 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5402) Mucin PF01456.17 KEG06029.1 - 0.017 15.1 2.7 0.017 15.1 2.7 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein HDV_ag PF01517.18 KEG06029.1 - 0.95 9.2 5.0 0.17 11.6 1.2 1.7 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen PEP-utilisers_N PF05524.13 KEG06029.1 - 1.1 9.5 15.5 0.22 11.7 1.1 3.3 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal RHSP PF07999.11 KEG06030.1 - 2.5e-85 286.9 0.3 3.7e-85 286.4 0.3 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein Mucin PF01456.17 KEG06032.1 - 0.0016 18.4 0.2 0.0016 18.4 0.2 1.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Mod_r PF07200.13 KEG06032.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein LAT PF15234.6 KEG06032.1 - 0.086 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Peptidase_M16_C PF05193.21 KEG06033.1 - 7.6e-23 81.5 0.0 1.1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEG06033.1 - 2.7e-06 27.4 0.0 4.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Hormone_recep PF00104.30 KEG06034.1 - 0.16 11.5 0.1 3.8 7.0 0.2 2.3 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Sugar_tr PF00083.24 KEG06037.1 - 8.9e-101 338.0 37.6 2.9e-63 214.3 21.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEG06037.1 - 2.5e-18 66.1 28.0 3e-15 56.0 27.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.8 KEG06037.1 - 0.00054 19.9 4.2 0.00054 19.9 4.2 2.8 3 0 0 3 3 3 1 Conserved membrane protein YqhR DSPc PF00782.20 KEG06038.1 - 8.4e-23 80.7 0.5 2.3e-09 37.2 0.5 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG06038.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEG06038.1 - 0.12 12.4 0.1 0.39 10.8 0.1 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate Mucin PF01456.17 KEG06039.1 - 8.2e-06 25.9 14.0 8.2e-06 25.9 14.0 3.7 2 1 1 3 3 3 2 Mucin-like glycoprotein Mucin PF01456.17 KEG06040.1 - 6.3e-09 36.0 9.1 6.3e-09 36.0 9.1 3.2 2 1 1 3 3 3 1 Mucin-like glycoprotein CcdB PF01845.17 KEG06040.1 - 0.13 12.5 0.1 0.42 10.9 0.1 1.8 1 0 0 1 1 1 0 CcdB protein DASH_Duo1 PF08651.10 KEG06040.1 - 0.18 11.6 1.0 13 5.6 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 Ferritin PF00210.24 KEG06040.1 - 0.39 10.7 9.2 0.059 13.3 1.1 3.1 2 1 0 3 3 3 0 Ferritin-like domain T3SSipB PF16535.5 KEG06040.1 - 0.69 10.4 39.3 0.88 10.0 14.3 3.2 2 1 1 3 3 3 0 Type III cell invasion protein SipB DUF3829 PF12889.7 KEG06040.1 - 0.82 9.1 11.4 4 6.8 3.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3829) zf-MYND PF01753.18 KEG06042.1 - 7.4e-09 35.6 16.6 1.4e-08 34.7 16.6 1.5 1 0 0 1 1 1 1 MYND finger PAX PF00292.18 KEG06042.1 - 0.017 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain CAP_N PF01213.19 KEG06042.1 - 1.8 7.9 4.4 4.4 6.7 4.4 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal V-SNARE_C PF12352.8 KEG06044.1 - 2.9e-05 24.3 5.8 9.3e-05 22.6 0.6 2.8 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KEG06044.1 - 8e-05 22.5 0.5 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 Sec20 H2O2_YaaD PF03883.14 KEG06044.1 - 0.084 12.4 0.5 0.14 11.6 0.4 1.5 1 1 0 1 1 1 0 Peroxide stress protein YaaA DIRP PF06584.13 KEG06044.1 - 0.11 12.7 1.5 0.23 11.7 1.5 1.7 1 1 0 1 1 1 0 DIRP ThiS PF02597.20 KEG06044.1 - 0.24 12.1 1.4 47 4.7 0.5 3.0 1 1 1 2 2 2 0 ThiS family DUF3450 PF11932.8 KEG06044.1 - 0.54 9.5 9.1 3.8 6.7 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phosphodiest PF01663.22 KEG06045.1 - 0.093 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1691 PF07950.11 KEG06045.1 - 0.11 13.2 1.8 0.18 12.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) RapH_N PF18801.1 KEG06046.1 - 0.095 12.8 0.2 0.095 12.8 0.2 2.9 3 0 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal AMP-binding PF00501.28 KEG06049.1 - 1.5e-82 277.4 0.3 5.3e-82 275.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Ank_2 PF12796.7 KEG06053.1 - 9.2e-05 23.0 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEG06053.1 - 0.0036 17.7 0.0 5.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat PRC2_HTH_1 PF18118.1 KEG06053.1 - 0.012 16.4 2.2 0.012 16.4 2.2 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain RPA43_OB PF17875.1 KEG06053.1 - 0.085 13.5 6.0 3.7 8.2 2.4 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I PT-TG PF14449.6 KEG06053.1 - 0.14 12.1 0.0 8.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Pre-toxin TG SAPS PF04499.15 KEG06053.1 - 0.15 10.8 2.5 0.15 10.9 1.8 1.2 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Myc_N PF01056.18 KEG06053.1 - 0.35 10.7 10.8 0.014 15.3 3.7 1.9 2 0 0 2 2 2 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 KEG06053.1 - 0.38 11.0 16.2 0.089 13.0 8.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 TLP-20 PF06088.11 KEG06053.1 - 0.46 10.4 3.5 0.75 9.7 0.7 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RPN2_C PF18004.1 KEG06053.1 - 0.61 10.0 11.8 0.052 13.5 5.3 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 KEG06053.1 - 0.67 9.2 13.4 0.071 12.4 7.6 1.9 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.6 KEG06053.1 - 0.73 9.5 16.0 0.85 9.3 8.0 2.4 2 0 0 2 2 2 0 FAM176 family RNA_pol_Rpc4 PF05132.14 KEG06053.1 - 1.1 9.6 4.5 0.99 9.8 2.1 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF688 PF05097.12 KEG06053.1 - 1.2 8.2 7.2 0.33 10.1 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF688) Afi1 PF07792.12 KEG06053.1 - 2.8 8.4 9.2 1.3 9.5 4.4 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pox_Ag35 PF03286.14 KEG06053.1 - 3.1 7.6 16.3 0.17 11.6 9.2 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CPSF100_C PF13299.6 KEG06053.1 - 3.4 7.8 6.7 6.5 6.9 3.5 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PGA2 PF07543.12 KEG06053.1 - 3.6 7.6 19.3 0.46 10.5 8.9 2.5 2 1 0 2 2 2 0 Protein trafficking PGA2 FYDLN_acid PF09538.10 KEG06053.1 - 5.8 7.7 18.3 2.9 8.6 11.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF724 PF05266.14 KEG06054.1 - 0.22 11.3 9.0 0.34 10.7 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2408 PF10303.9 KEG06054.1 - 0.5 10.9 12.7 0.83 10.2 12.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Atg14 PF10186.9 KEG06054.1 - 0.61 9.1 16.8 0.88 8.6 16.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 C_Hendra PF16821.5 KEG06054.1 - 1.5 8.7 8.6 0.17 11.7 2.2 2.1 1 1 1 2 2 2 0 C protein from hendra and measles viruses Hid1 PF12722.7 KEG06054.1 - 6.8 4.7 8.0 9.4 4.2 8.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FapA PF03961.13 KEG06054.1 - 8.1 4.9 9.1 6.3 5.3 7.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A PCRF PF03462.18 KEG06054.1 - 8.1 6.3 16.4 6.9 6.5 7.1 2.2 1 1 1 2 2 2 0 PCRF domain FAM176 PF14851.6 KEG06055.1 - 1.1 8.9 13.4 4 7.1 0.1 3.6 4 0 0 4 4 4 0 FAM176 family Glyco_transf_10 PF00852.19 KEG06056.1 - 3.7e-12 46.3 0.2 3.7e-12 46.3 0.2 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Dala_Dala_lig_C PF07478.13 KEG06057.1 - 4e-15 55.9 0.0 6.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 KEG06057.1 - 3.9e-07 30.6 0.3 1.6e-06 28.6 0.0 2.3 3 0 0 3 3 3 1 SET domain ATP-grasp_3 PF02655.14 KEG06057.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KEG06057.1 - 0.00014 21.2 0.0 0.00039 19.8 0.0 1.7 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KEG06057.1 - 0.003 17.2 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KEG06057.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KEG06057.1 - 0.035 13.7 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.19 KEG06057.1 - 0.083 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CcmD PF04995.14 KEG06059.1 - 2.7 8.2 7.5 0.36 10.9 2.5 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Yip1 PF04893.17 KEG06060.1 - 1.1e-16 61.1 19.8 1.3e-16 60.8 19.8 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KEG06060.1 - 0.0018 18.1 10.6 0.0034 17.2 10.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) YIF1 PF03878.15 KEG06060.1 - 0.21 11.1 3.7 0.26 10.8 3.7 1.2 1 0 0 1 1 1 0 YIF1 DUF2842 PF11003.8 KEG06060.1 - 5.5 7.3 14.5 2 8.7 3.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) RNase_PH PF01138.21 KEG06061.1 - 9.2e-10 39.1 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF4691 PF15762.5 KEG06062.1 - 0.02 15.0 0.6 0.02 15.0 0.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4691) DUF3287 PF11690.8 KEG06063.1 - 0.03 14.0 1.3 0.059 13.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DLIC PF05783.11 KEG06063.1 - 0.14 11.0 1.4 0.16 10.7 0.1 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) NAP PF00956.18 KEG06063.1 - 0.41 9.8 3.4 0.79 8.8 3.4 1.5 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) UvrD_C PF13361.6 KEG06065.1 - 4.8e-31 108.4 0.1 1.8e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KEG06065.1 - 8.7e-21 74.7 0.0 1.7e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KEG06065.1 - 4.7e-10 39.1 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KEG06065.1 - 3.8e-09 37.0 0.0 1.3e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KEG06065.1 - 2e-08 34.3 0.0 0.00076 19.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KEG06065.1 - 0.0014 18.3 0.0 0.049 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEG06065.1 - 0.0036 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain V-set_2 PF15910.5 KEG06065.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 ICOS V-set domain PhoH PF02562.16 KEG06065.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF3634 PF12321.8 KEG06067.1 - 0.085 13.2 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) Epimerase PF01370.21 KEG06068.1 - 1.1e-18 67.6 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEG06068.1 - 1.6e-15 57.4 0.0 2.4e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEG06068.1 - 7.6e-10 38.4 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEG06068.1 - 1.8e-05 24.0 0.0 0.00033 19.9 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEG06068.1 - 0.0072 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KEG06068.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 KR domain LRR_4 PF12799.7 KEG06070.1 - 1.6e-11 44.2 1.6 0.055 13.9 0.0 5.2 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG06070.1 - 4.1e-07 29.5 3.0 0.0054 16.7 0.0 5.9 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.6 KEG06070.1 - 4.6e-06 26.3 5.8 0.18 11.6 0.4 4.7 4 3 0 4 4 4 2 Leucine rich repeat LisH_TPL PF17814.1 KEG06070.1 - 0.00055 19.5 0.6 1.2 8.9 0.1 2.7 2 0 0 2 2 2 2 LisH-like dimerisation domain LRR_9 PF14580.6 KEG06070.1 - 0.051 13.1 0.9 12 5.3 0.1 3.0 2 2 2 4 4 4 0 Leucine-rich repeat Oest_recep PF02159.15 KEG06071.1 - 2.3 8.7 12.1 0.38 11.3 1.6 2.3 2 0 0 2 2 2 0 Oestrogen receptor Kinesin PF00225.23 KEG06072.1 - 1.4e-43 149.1 0.7 2.8e-43 148.1 0.7 1.5 1 0 0 1 1 1 1 Kinesin motor domain Fzo_mitofusin PF04799.13 KEG06072.1 - 0.054 13.0 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 fzo-like conserved region Surfac_D-trimer PF09006.11 KEG06072.1 - 0.072 13.0 2.7 0.15 12.0 0.7 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation YlqD PF11068.8 KEG06072.1 - 0.1 13.0 0.2 0.1 13.0 0.2 3.0 3 0 0 3 3 3 0 YlqD protein SUIM_assoc PF16619.5 KEG06072.1 - 0.97 9.5 12.4 3.4 7.8 1.4 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 YabA PF06156.13 KEG06072.1 - 1.3 9.7 9.3 0.14 12.8 1.6 2.7 3 0 0 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 KEG06072.1 - 3.3 7.9 18.7 0.47 10.6 0.8 3.2 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF2219 PF09982.9 KEG06074.1 - 0.006 15.9 0.2 0.0091 15.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2219) His_Phos_2 PF00328.22 KEG06074.1 - 0.044 13.1 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) TraL PF07178.11 KEG06074.1 - 0.065 13.7 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 TraL protein 3HCDH_N PF02737.18 KEG06075.1 - 8.4e-50 169.1 0.1 1.1e-49 168.8 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEG06075.1 - 6.5e-34 116.4 0.1 1.7e-33 115.1 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ADH_zinc_N PF00107.26 KEG06075.1 - 0.0013 18.7 0.0 0.005 16.8 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase SET PF00856.28 KEG06076.1 - 3.6e-11 43.7 0.0 5.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-Mss51 PF13824.6 KEG06076.1 - 0.00055 20.0 2.1 0.00055 20.0 2.1 2.2 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KEG06076.1 - 0.00085 19.4 2.7 0.00085 19.4 2.7 3.4 4 1 0 4 4 4 1 MYND finger DUF676 PF05057.14 KEG06077.1 - 3e-10 40.0 0.0 2.8e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KEG06077.1 - 0.0076 16.1 0.0 0.058 13.2 0.0 1.9 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Hid1 PF12722.7 KEG06079.1 - 3.9 5.5 11.6 5.4 5.0 11.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2076 PF09849.9 KEG06080.1 - 0.023 14.7 7.5 0.059 13.4 7.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Med9 PF07544.13 KEG06080.1 - 0.1 12.7 15.5 0.66 10.1 0.7 3.7 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Tup_N PF08581.10 KEG06080.1 - 1.4 9.2 8.4 0.37 11.1 4.2 2.2 2 0 0 2 2 2 0 Tup N-terminal PspB PF06667.12 KEG06080.1 - 2.1 8.4 5.5 3.9 7.6 1.8 3.1 3 0 0 3 3 3 0 Phage shock protein B DeoC PF01791.9 KEG06082.1 - 6e-11 42.4 2.4 9.2e-11 41.8 2.4 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase HTH_30 PF13556.6 KEG06083.1 - 0.028 14.2 0.1 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Virulence_fact PF13769.6 KEG06083.1 - 0.058 13.6 0.9 0.097 12.9 0.9 1.3 1 0 0 1 1 1 0 Virulence factor ASFV_J13L PF05568.11 KEG06084.1 - 0.05 13.4 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein SIT PF15330.6 KEG06084.1 - 0.082 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT YajC PF02699.15 KEG06084.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Hydrolase PF00702.26 KEG06087.1 - 3.2e-08 34.1 0.0 4.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEG06087.1 - 4.8e-05 23.2 0.1 6.1e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEG06089.1 - 1.9e-15 56.3 0.0 3.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus CactinC_cactus PF09732.9 KEG06091.1 - 7.7e-39 132.5 0.5 1.2e-38 131.9 0.5 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Peptidase_M8 PF01457.16 KEG06093.1 - 0.00043 19.1 0.1 0.00055 18.8 0.1 1.2 1 0 0 1 1 1 1 Leishmanolysin RHSP PF07999.11 KEG06094.1 - 9.3e-87 291.6 0.4 1.5e-86 291.0 0.4 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.6 KEG06094.1 - 0.012 15.0 0.0 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 Macro-like domain Alpha_kinase PF02816.18 KEG06095.1 - 5.6e-54 183.1 0.8 7.1e-54 182.7 0.8 1.1 1 0 0 1 1 1 1 Alpha-kinase family RAP80_UIM PF18282.1 KEG06095.1 - 0.031 14.0 0.6 0.4 10.5 0.1 2.3 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Galactosyl_T PF01762.21 KEG06097.1 - 3.3e-06 27.1 0.0 0.32 10.8 0.0 3.6 3 1 0 3 3 3 2 Galactosyltransferase CPT_N PF16484.5 KEG06097.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus DUF3806 PF12713.7 KEG06098.1 - 0.085 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Pkinase PF00069.25 KEG06099.1 - 1.1e-16 60.9 0.0 1.1e-16 60.9 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KEG06099.1 - 1e-08 34.4 1.0 2.1e-08 33.3 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KEG06099.1 - 1.2e-08 34.5 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG06099.1 - 3.7e-05 23.8 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2681 PF10883.8 KEG06099.1 - 0.35 11.3 9.1 4.6 7.7 7.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Pkinase PF00069.25 KEG06100.1 - 7.1e-18 64.9 0.0 8.5e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06100.1 - 4.2e-09 36.1 0.0 4.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG06100.1 - 8.1e-07 28.2 0.2 1.2e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG06100.1 - 0.01 15.2 0.7 0.014 14.7 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG06100.1 - 0.16 11.9 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 KEG06102.1 - 2.6e-48 164.1 0.3 3e-48 163.9 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG06102.1 - 7.7e-34 117.3 0.5 1e-33 116.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG06102.1 - 4.4e-18 65.8 1.2 5.7e-18 65.5 1.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEG06102.1 - 6e-06 25.6 0.2 9.1e-06 25.0 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEG06102.1 - 0.0013 18.7 2.0 0.0019 18.1 2.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEG06102.1 - 0.0019 17.7 0.8 0.012 15.1 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEG06102.1 - 0.0022 17.5 0.0 0.0067 15.9 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 KEG06102.1 - 0.035 14.0 0.3 0.051 13.5 0.3 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3Beta_HSD PF01073.19 KEG06102.1 - 0.078 12.0 0.2 0.12 11.4 0.2 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF5446 PF17522.2 KEG06106.1 - 2.6 8.3 6.2 3.1 8.1 4.4 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5446) SET PF00856.28 KEG06108.1 - 7.9e-11 42.6 0.0 9.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 SET domain Phospholip_B PF04916.13 KEG06109.1 - 5.2e-37 127.6 0.1 5.9e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B Ion_trans_2 PF07885.16 KEG06109.1 - 0.052 13.5 0.3 0.092 12.7 0.3 1.3 1 0 0 1 1 1 0 Ion channel SKG6 PF08693.10 KEG06109.1 - 0.074 12.5 1.4 0.12 11.8 1.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain K_channel_TID PF07941.11 KEG06110.1 - 8.7 6.9 11.9 13 6.3 1.4 2.2 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HCV_NS5a_1a PF08300.13 KEG06112.1 - 0.0067 16.5 0.6 0.087 12.9 0.0 2.1 1 1 1 2 2 2 2 Hepatitis C virus non-structural 5a zinc finger domain SURF6 PF04935.12 KEG06116.1 - 3.4e-17 62.9 2.5 3.4e-17 62.9 2.5 2.0 1 1 1 2 2 2 1 Surfeit locus protein 6 FUSC PF04632.12 KEG06116.1 - 4.3 5.8 5.5 5.1 5.5 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bax1-I PF01027.20 KEG06117.1 - 3e-40 138.3 16.4 4.8e-40 137.6 16.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KEG06117.1 - 0.00059 19.5 12.7 0.0009 18.9 12.7 1.5 1 1 0 1 1 1 1 Bax inhibitor 1 like PetG PF02529.15 KEG06117.1 - 0.79 9.6 3.9 0.49 10.3 0.6 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 NOG1_N PF17835.1 KEG06119.1 - 0.17 11.8 6.1 2.4 8.1 0.1 3.0 2 1 0 2 2 2 0 NOG1 N-terminal helical domain DUF948 PF06103.11 KEG06119.1 - 8 6.8 32.0 4.1 7.7 0.9 6.1 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.14 KEG06119.1 - 9.1 6.2 12.7 0.89 9.4 2.2 3.3 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF2935 PF11155.8 KEG06119.1 - 9.7 6.6 9.2 3.4 8.0 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Exo_endo_phos_2 PF14529.6 KEG06120.1 - 4.7e-12 45.8 0.1 6.8e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase 6PF2K PF01591.18 KEG06121.1 - 4.7e-35 120.9 0.0 7.5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEG06121.1 - 9.1e-18 64.6 0.0 1.3e-10 41.3 0.0 2.6 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) Ank_4 PF13637.6 KEG06121.1 - 1.6e-15 57.2 0.2 6.6e-08 33.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG06121.1 - 9.4e-15 55.0 0.2 3.4e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG06121.1 - 1.8e-12 47.2 0.4 8.8e-12 45.0 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KEG06121.1 - 2.8e-10 40.1 0.4 7.2e-06 26.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KEG06121.1 - 3.5e-06 26.9 0.0 0.0027 18.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.6 KEG06121.1 - 4e-06 27.0 0.0 9.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KEG06121.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 KEG06121.1 - 0.078 12.6 0.0 1.3 8.6 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.10 KEG06121.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF371 PF04027.13 KEG06122.1 - 0.068 13.1 2.3 0.12 12.3 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF371) Alanine_zipper PF11839.8 KEG06122.1 - 0.11 12.9 15.1 0.5 10.8 5.3 2.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein CK_II_beta PF01214.18 KEG06127.1 - 2.5e-73 245.8 0.0 3.1e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PDEase_I PF00233.19 KEG06128.1 - 2.8e-76 256.4 0.0 1.1e-74 251.1 0.0 2.0 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Syntaxin-18_N PF10496.9 KEG06128.1 - 0.061 13.6 0.1 20 5.5 0.0 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus GAF_2 PF13185.6 KEG06129.1 - 0.027 14.8 0.0 0.073 13.4 0.0 1.7 1 1 0 1 1 1 0 GAF domain DUF4736 PF15883.5 KEG06129.1 - 0.074 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Aminotran_1_2 PF00155.21 KEG06131.1 - 9e-34 117.2 0.0 1.1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HutD PF05962.11 KEG06132.1 - 0.17 11.8 0.3 1.1 9.2 0.0 2.3 2 1 1 3 3 3 0 HutD TFIIS_C PF01096.18 KEG06133.1 - 1.2e-16 60.2 6.8 2.1e-16 59.5 6.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KEG06133.1 - 0.0065 16.4 1.3 0.013 15.4 1.3 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1610 PF07754.11 KEG06133.1 - 0.04 13.9 0.6 0.076 13.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DCAF15_WD40 PF14939.6 KEG06133.1 - 0.17 11.5 1.5 0.23 11.1 1.5 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Sgf11 PF08209.11 KEG06133.1 - 0.31 10.7 2.5 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PWWP PF00855.17 KEG06134.1 - 6e-11 42.6 0.0 6e-11 42.6 0.0 2.1 3 0 0 3 3 3 1 PWWP domain DUF4604 PF15377.6 KEG06134.1 - 0.038 14.4 20.8 0.065 13.7 20.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Med26 PF08711.11 KEG06134.1 - 0.047 13.7 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Zip PF02535.22 KEG06134.1 - 4.9 6.3 7.9 7.4 5.7 7.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter START PF01852.19 KEG06135.1 - 3.6e-06 26.6 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 START domain WD40 PF00400.32 KEG06136.1 - 3e-05 24.7 1.0 0.00062 20.5 0.5 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG06136.1 - 0.029 14.6 0.8 0.079 13.3 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 KEG06137.1 - 8.5e-76 254.8 0.0 9.9e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06137.1 - 4.5e-37 127.7 0.0 5.5e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06137.1 - 3.2e-09 36.5 0.0 4.7e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 KEG06137.1 - 3.9e-05 23.3 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KEG06137.1 - 0.00066 19.1 0.3 0.001 18.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEG06137.1 - 0.00068 18.7 0.4 0.00099 18.2 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG06137.1 - 0.054 13.4 0.3 0.83 9.5 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3782 PF12644.7 KEG06140.1 - 0.13 12.5 0.5 0.21 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Mga PF05043.13 KEG06141.1 - 0.29 11.8 1.4 13 6.4 0.0 2.7 2 0 0 2 2 2 0 Mga helix-turn-helix domain zf-RING_5 PF14634.6 KEG06142.1 - 7.2e-05 22.7 14.9 0.00011 22.0 14.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KEG06142.1 - 0.14 12.0 16.5 0.23 11.4 16.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEG06142.1 - 0.14 12.0 13.5 0.27 11.1 13.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG06142.1 - 0.23 11.3 14.3 0.43 10.5 14.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4200 PF13863.6 KEG06143.1 - 2.6e-21 76.2 21.2 2.6e-21 76.2 21.2 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) LMBR1 PF04791.16 KEG06143.1 - 0.32 9.8 14.5 0.53 9.1 14.5 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein RNA_replicase_B PF03431.13 KEG06143.1 - 0.71 8.3 7.6 0.042 12.3 1.9 1.7 1 1 1 2 2 2 0 RNA replicase, beta-chain FapA PF03961.13 KEG06143.1 - 3 6.4 17.4 0.05 12.2 6.0 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Atg14 PF10186.9 KEG06143.1 - 7.8 5.5 34.2 3 6.8 6.0 3.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 KEG06145.1 - 0.042 13.9 0.4 0.063 13.4 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GTP_EFTU_D3 PF03143.17 KEG06147.1 - 9.4e-28 96.8 0.1 2.9e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 KEG06147.1 - 6.7e-12 45.4 0.0 1.5e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEG06147.1 - 9.6e-06 25.9 0.5 2.6e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 60KD_IMP PF02096.20 KEG06148.1 - 4.8e-10 39.6 0.1 8.5e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Leu_zip PF15294.6 KEG06149.1 - 0.059 12.9 0.1 0.071 12.6 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper DUF4630 PF15443.6 KEG06149.1 - 0.1 12.8 2.5 0.13 12.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) DEC-1_N PF04625.13 KEG06150.1 - 7.4 5.5 9.0 9.5 5.1 9.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glycos_transf_1 PF00534.20 KEG06153.1 - 3.1e-12 46.3 0.0 1.4e-11 44.2 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEG06153.1 - 2.5e-11 44.1 0.0 1.5e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEG06153.1 - 3.1e-07 30.7 0.1 5.1e-06 26.8 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 KEG06153.1 - 0.0054 15.4 0.0 0.008 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KEG06153.1 - 0.0098 15.9 0.1 0.036 14.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Geminin PF07412.12 KEG06153.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Geminin Glyco_trans_4_4 PF13579.6 KEG06153.1 - 1 9.8 4.8 3.4 8.1 0.1 3.3 3 1 1 4 4 4 0 Glycosyl transferase 4-like domain Cpn60_TCP1 PF00118.24 KEG06154.1 - 2.3e-159 531.1 9.7 2.7e-159 530.9 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family VPS11_C PF12451.8 KEG06156.1 - 8.4e-06 25.9 0.7 2.7e-05 24.3 0.7 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KEG06156.1 - 8.7e-05 22.5 12.1 0.00017 21.5 12.1 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KEG06156.1 - 0.02 14.8 9.8 0.067 13.1 9.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KEG06156.1 - 0.045 13.6 1.3 0.11 12.4 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KEG06156.1 - 0.049 13.7 5.6 0.14 12.2 5.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KEG06156.1 - 0.086 12.8 9.6 0.2 11.7 9.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Nsp2a_N PF17896.1 KEG06156.1 - 0.11 11.7 0.1 0.2 10.8 0.0 1.4 2 0 0 2 2 2 0 Replicase polyprotein 1a N-terminal domain zf-rbx1 PF12678.7 KEG06156.1 - 0.16 12.3 6.1 0.5 10.7 6.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEG06156.1 - 0.32 11.1 2.9 0.79 9.8 2.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KEG06156.1 - 1.4 9.3 11.0 4.3 7.8 11.0 1.9 1 0 0 1 1 1 0 Ring finger domain Acyl-CoA_dh_1 PF00441.24 KEG06159.1 - 4.1e-25 88.7 2.4 5.5e-25 88.3 2.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEG06159.1 - 4.2e-12 46.1 0.0 2.6e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEG06159.1 - 9.4e-08 32.4 1.2 1.9e-07 31.4 1.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Actin PF00022.19 KEG06160.1 - 2.5e-38 131.8 0.0 1.4e-36 126.0 0.0 2.1 1 1 0 1 1 1 1 Actin Fanconi_C PF02106.15 KEG06160.1 - 0.0061 15.3 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Fanconi anaemia group C protein SPRY PF00622.28 KEG06161.1 - 8.4e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain ALMT PF11744.8 KEG06161.1 - 2.9 6.6 7.2 5.3 5.8 7.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ATP-gua_PtransN PF02807.15 KEG06163.1 - 5.4e-32 110.0 0.0 8.1e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain FmdE PF02663.14 KEG06164.1 - 0.052 13.6 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon MAP70 PF07058.11 KEG06164.1 - 3.8 6.1 7.0 6.1 5.4 7.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 Ax_dynein_light PF10211.9 KEG06165.1 - 4.6e-47 160.4 3.9 6e-47 160.0 3.9 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF3958 PF13125.6 KEG06165.1 - 0.012 15.8 2.3 0.012 15.8 2.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3958) FAM184 PF15665.5 KEG06165.1 - 0.013 15.3 9.1 0.021 14.6 9.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF4211 PF13926.6 KEG06165.1 - 0.032 14.3 0.4 0.063 13.3 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) DUF4635 PF15466.6 KEG06165.1 - 0.047 13.2 4.1 0.036 13.6 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) bZIP_2 PF07716.15 KEG06165.1 - 0.085 13.0 12.2 1.5 8.9 2.6 2.6 1 1 1 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 KEG06165.1 - 0.093 13.1 6.1 2.1 8.8 2.0 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 KEG06165.1 - 0.15 12.3 7.2 0.3 11.3 7.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 KEG06165.1 - 0.19 11.0 5.6 0.31 10.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RRP36 PF06102.12 KEG06165.1 - 0.2 11.6 5.4 0.32 10.9 5.4 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF1664 PF07889.12 KEG06165.1 - 0.21 11.6 2.7 0.36 10.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ApoO PF09769.9 KEG06165.1 - 0.35 10.8 1.5 0.71 9.8 0.9 1.8 1 1 1 2 2 2 0 Apolipoprotein O Uso1_p115_C PF04871.13 KEG06165.1 - 0.36 11.2 6.4 0.64 10.4 6.4 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region WD40_alt PF14077.6 KEG06165.1 - 0.59 10.0 7.2 1 9.3 0.5 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF5082 PF16888.5 KEG06165.1 - 0.76 10.1 6.3 5.9 7.2 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 KEG06165.1 - 1.3 9.1 12.8 0.95 9.5 2.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KEG06165.1 - 2.1 8.9 9.8 4 8.0 9.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Cauli_AT PF03233.13 KEG06165.1 - 3.1 7.7 5.3 6.1 6.7 4.6 1.6 1 1 1 2 2 2 0 Aphid transmission protein HALZ PF02183.18 KEG06165.1 - 4.7 7.5 6.7 3.6 7.9 1.1 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper RNase_H PF00075.24 KEG06166.1 - 8e-06 26.1 0.0 4.2e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 RNase H TetR_C_1 PF02909.17 KEG06169.1 - 0.11 12.4 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Peripla_BP_6 PF13458.6 KEG06170.1 - 3.3e-08 33.6 0.0 4.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Metallophos PF00149.28 KEG06177.1 - 9.1e-28 98.1 0.1 1.9e-27 97.1 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 KEG06177.1 - 0.00047 19.9 0.1 0.2 11.7 0.0 4.2 5 1 1 6 6 6 1 EF-hand domain EF-hand_1 PF00036.32 KEG06177.1 - 0.023 14.2 0.3 2.6 7.8 0.0 3.7 4 0 0 4 4 4 0 EF hand zf-U11-48K PF05253.12 KEG06177.1 - 0.12 12.3 1.8 0.2 11.6 0.8 2.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger zf-TRAF PF02176.18 KEG06177.1 - 0.25 12.1 13.0 0.72 10.6 13.0 1.9 1 0 0 1 1 1 0 TRAF-type zinc finger zf-ribbon_3 PF13248.6 KEG06177.1 - 0.46 10.0 5.3 2.1 7.8 2.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEG06177.1 - 0.69 10.1 4.6 1.7 8.8 4.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Herpes_UL69 PF05459.12 KEG06177.1 - 1.2 8.5 4.9 2 7.7 3.9 1.8 2 0 0 2 2 2 0 Herpesvirus transcriptional regulator family DZR PF12773.7 KEG06177.1 - 1.5 8.9 10.1 3 8.0 10.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon E1-E2_ATPase PF00122.20 KEG06179.1 - 9.7e-42 142.5 4.6 2.9e-41 141.0 2.5 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KEG06179.1 - 2.6e-33 116.1 3.7 4.7e-33 115.3 3.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEG06179.1 - 7.3e-23 80.8 1.1 4.5e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KEG06179.1 - 2.2e-07 30.9 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEG06179.1 - 0.0031 17.9 0.1 0.015 15.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEG06179.1 - 0.11 12.6 0.1 0.51 10.4 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mucin PF01456.17 KEG06180.1 - 1.5e-07 31.5 44.7 5.1e-05 23.3 9.1 3.4 1 1 1 3 3 3 2 Mucin-like glycoprotein DUF4349 PF14257.6 KEG06180.1 - 0.026 14.0 1.8 0.045 13.2 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF1738 PF08401.11 KEG06180.1 - 1.1 9.4 4.5 1.4 9.0 0.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1738) UPF0158 PF03682.13 KEG06182.1 - 0.053 13.5 0.7 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) VPS53_C PF16854.5 KEG06182.1 - 0.1 12.5 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus YabA PF06156.13 KEG06182.1 - 6.2 7.5 6.2 2.8 8.6 1.0 2.8 3 0 0 3 3 3 0 Initiation control protein YabA p25-alpha PF05517.12 KEG06183.1 - 5.1e-38 130.7 3.7 5.7e-38 130.5 3.7 1.0 1 0 0 1 1 1 1 p25-alpha FtsH_ext PF06480.15 KEG06183.1 - 0.035 14.5 0.0 0.082 13.3 0.0 1.6 1 1 0 1 1 1 0 FtsH Extracellular PTP_tm PF18861.1 KEG06184.1 - 0.00014 21.9 2.0 0.00032 20.7 2.0 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD34_antigen PF06365.12 KEG06184.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Syndecan PF01034.20 KEG06184.1 - 0.043 13.7 1.5 0.086 12.8 1.5 1.4 1 0 0 1 1 1 0 Syndecan domain RBB1NT PF08169.11 KEG06184.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 RBB1NT (NUC162) domain DUF1129 PF06570.11 KEG06185.1 - 0.37 10.3 1.3 0.55 9.7 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TssN PF17555.2 KEG06185.1 - 0.66 9.3 7.0 0.23 10.8 3.8 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssN MFS_1 PF07690.16 KEG06186.1 - 2e-16 59.9 22.8 2.3e-16 59.7 22.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG06186.1 - 0.00013 21.6 15.6 0.001 18.6 15.6 2.2 1 1 0 1 1 1 1 Nodulin-like LapA_dom PF06305.11 KEG06186.1 - 0.24 11.2 0.0 0.24 11.2 0.0 3.3 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Herpes_UL52 PF03121.15 KEG06188.1 - 5.5e-12 45.4 0.1 1.4e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase zf-C2H2_4 PF13894.6 KEG06190.1 - 4.3 8.4 12.6 0.4 11.7 1.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger FAM176 PF14851.6 KEG06191.1 - 0.2 11.3 4.3 0.29 10.8 4.3 1.2 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KEG06191.1 - 4.8 7.6 9.3 1.3 9.5 5.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BUD22 PF09073.10 KEG06192.1 - 0.024 14.0 1.7 0.035 13.5 1.7 1.3 1 0 0 1 1 1 0 BUD22 Di19_C PF14571.6 KEG06192.1 - 0.04 14.4 8.1 0.62 10.6 0.1 2.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal C1_2 PF03107.16 KEG06192.1 - 0.19 12.1 4.3 0.24 11.7 0.7 2.5 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 KEG06192.1 - 0.55 10.2 9.6 1.6 8.7 9.6 1.8 1 1 0 1 1 1 0 PHD-finger SPT6_acidic PF14632.6 KEG06192.1 - 3.8 8.2 7.3 0.2 12.3 1.3 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Gly_kinase PF02595.15 KEG06194.1 - 9e-10 38.1 0.0 1.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Glycerate kinase family ELO PF01151.18 KEG06196.1 - 8.3e-81 271.2 25.9 1e-80 270.9 25.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.8 KEG06196.1 - 0.0097 16.0 1.3 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TMEM132D_C PF15706.5 KEG06196.1 - 5.5 6.8 5.5 1.1 9.1 1.6 1.8 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term zf_CCCH_4 PF18345.1 KEG06197.1 - 0.021 14.9 0.3 0.046 13.8 0.3 1.6 1 0 0 1 1 1 0 Zinc finger domain HECT PF00632.25 KEG06198.1 - 1.9e-91 306.8 0.0 2.9e-91 306.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 KEG06198.1 - 0.0024 18.1 6.2 0.0052 17.1 6.2 1.6 1 0 0 1 1 1 1 C1 domain zf-primase PF09329.11 KEG06198.1 - 0.041 13.7 0.3 1 9.2 0.1 2.5 2 0 0 2 2 2 0 Primase zinc finger DM PF00751.18 KEG06198.1 - 0.46 10.4 2.1 1.3 8.9 2.1 1.8 1 0 0 1 1 1 0 DM DNA binding domain zf-B_box PF00643.24 KEG06198.1 - 4.7 7.5 7.3 65 3.8 7.3 2.7 1 1 1 2 2 2 0 B-box zinc finger ZZ PF00569.17 KEG06198.1 - 9.4 6.1 9.3 0.83 9.5 4.1 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Nop PF01798.18 KEG06199.1 - 4.7e-80 268.4 0.4 9.2e-80 267.4 0.0 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KEG06199.1 - 6.5e-16 58.5 0.1 1.9e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 NOP5NT (NUC127) domain MSP1_C PF07462.11 KEG06199.1 - 0.029 13.1 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-Tim10_DDP PF02953.15 KEG06202.1 - 0.0072 16.0 0.2 0.011 15.3 0.2 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.25 KEG06203.1 - 5.1e-27 94.9 0.0 1.4e-17 64.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06203.1 - 0.011 15.0 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase Kdo PF06293.14 KEG06203.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KEG06203.1 - 0.27 10.2 0.0 0.38 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FlgD PF03963.14 KEG06204.1 - 0.022 15.0 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region SLX9 PF15341.6 KEG06208.1 - 0.074 13.5 18.8 2.8 8.3 18.8 2.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Abhydrolase_1 PF00561.20 KEG06209.1 - 1.5e-21 77.2 0.0 4.6e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG06209.1 - 3.2e-13 49.5 0.1 0.00026 20.3 0.0 3.1 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEG06209.1 - 1.6e-07 32.2 10.2 3.4e-07 31.1 10.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KEG06209.1 - 2.2e-05 24.5 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 KEG06209.1 - 0.00017 21.2 0.0 0.095 12.2 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.9 KEG06209.1 - 0.00047 19.7 1.1 0.0051 16.3 0.6 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase Ndr PF03096.14 KEG06209.1 - 0.0051 15.5 0.0 0.0083 14.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KEG06209.1 - 0.008 15.9 0.3 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KEG06209.1 - 0.019 14.8 0.0 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KEG06209.1 - 0.025 14.7 0.2 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain PIN PF01850.21 KEG06209.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 PIN domain DUF2048 PF09752.9 KEG06209.1 - 0.11 11.6 0.0 0.28 10.2 0.1 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 LRR_4 PF12799.7 KEG06210.1 - 6.9e-06 26.3 6.3 0.046 14.1 6.3 3.6 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG06210.1 - 1.9e-05 24.3 5.0 0.1 12.4 3.5 3.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KEG06210.1 - 0.00014 21.7 2.4 0.46 10.7 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 KEG06210.1 - 0.014 14.9 0.5 0.027 14.0 0.4 1.5 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 KEG06210.1 - 0.053 14.1 7.4 4.5 8.2 1.0 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat RhoGEF PF00621.20 KEG06211.1 - 1.6e-07 31.7 0.0 3.7e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain PDEase_I PF00233.19 KEG06213.1 - 8.6e-25 87.8 0.0 1.5e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TGS PF02824.21 KEG06213.1 - 0.13 12.3 0.1 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 TGS domain SRP-alpha_N PF04086.13 KEG06215.1 - 2.7 7.9 7.0 0.22 11.4 1.9 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal VIR_N PF15912.5 KEG06216.1 - 1.2 8.7 3.7 2.9 7.4 0.2 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal TPR_2 PF07719.17 KEG06218.1 - 5.2e-05 23.0 4.6 1.2 9.4 0.0 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG06218.1 - 0.00077 19.9 1.2 0.54 11.0 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG06218.1 - 0.003 18.2 12.3 0.61 11.1 1.7 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG06218.1 - 0.004 17.8 9.0 0.004 17.8 9.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG06218.1 - 0.0089 16.3 9.0 0.025 14.8 3.6 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG06218.1 - 0.021 15.2 0.0 0.021 15.2 0.0 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG06218.1 - 0.051 14.1 2.2 3.3 8.3 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEG06218.1 - 0.062 14.0 0.1 0.062 14.0 0.1 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG06218.1 - 0.11 12.4 9.5 0.4 10.6 0.4 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 KEG06218.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TPR_11 PF13414.6 KEG06218.1 - 0.11 12.2 0.6 0.58 9.9 0.3 2.1 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KEG06218.1 - 3 8.1 8.2 9.6 6.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG06218.1 - 9.8 6.4 10.2 1.3 9.2 5.0 2.2 2 1 1 3 3 2 0 Tetratricopeptide repeat Mucin PF01456.17 KEG06220.1 - 2.1e-08 34.3 53.5 0.002 18.1 28.8 3.5 1 1 1 2 2 2 2 Mucin-like glycoprotein UPF0556 PF10572.9 KEG06220.1 - 0.04 13.4 0.4 0.35 10.4 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0556 Mucin PF01456.17 KEG06221.1 - 2.7e-07 30.7 1.2 3.2e-07 30.4 1.2 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein SMBP PF16785.5 KEG06221.1 - 3.7 7.8 17.8 5.8 7.2 17.8 1.3 1 1 0 1 1 1 0 Small metal-binding protein Retrotran_gag_2 PF14223.6 KEG06222.1 - 0.0035 17.0 0.6 0.0067 16.1 0.6 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AAA_23 PF13476.6 KEG06222.1 - 0.0074 16.8 1.0 0.015 15.8 1.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0449 PF15136.6 KEG06222.1 - 0.027 14.9 0.7 0.079 13.4 0.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF1942 PF09167.11 KEG06222.1 - 0.04 13.9 0.9 0.13 12.2 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Spc7 PF08317.11 KEG06222.1 - 0.4 9.5 7.0 0.65 8.8 7.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CheZ PF04344.13 KEG06222.1 - 0.76 9.7 6.0 1.9 8.4 4.5 2.1 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ V_ATPase_I PF01496.19 KEG06222.1 - 1.1 7.1 3.5 1.4 6.7 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Muted PF14942.6 KEG06222.1 - 2 8.7 9.0 0.097 13.0 2.7 2.0 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein PRP38 PF03371.15 KEG06223.1 - 0.00053 19.9 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 PRP38 family PPP4R2 PF09184.11 KEG06224.1 - 8.9e-05 22.2 0.1 0.00019 21.1 0.0 1.5 2 1 0 2 2 2 1 PPP4R2 SSP160 PF06933.11 KEG06224.1 - 0.076 11.2 0.6 0.11 10.7 0.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peripla_BP_6 PF13458.6 KEG06225.1 - 6.2e-09 36.0 0.0 1.1e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein DUF3560 PF12083.8 KEG06229.1 - 0.063 13.4 7.2 0.13 12.4 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) MT0933_antitox PF14013.6 KEG06229.1 - 0.19 12.1 3.5 0.19 12.0 1.6 2.1 2 0 0 2 2 2 0 MT0933-like antitoxin protein APG6_N PF17675.1 KEG06229.1 - 0.22 12.0 5.1 0.37 11.3 5.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5600 PF18150.1 KEG06231.1 - 0.018 15.6 0.3 0.046 14.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Met_synt_B12 PF02965.17 KEG06231.1 - 3.3 7.1 12.0 0.45 9.9 0.9 2.7 2 1 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain zf-C4H2 PF10146.9 KEG06231.1 - 3.5 7.9 9.7 0.29 11.4 0.2 2.6 2 1 1 3 3 3 0 Zinc finger-containing protein GARP PF16731.5 KEG06231.1 - 4.7 6.9 52.8 0.066 12.9 11.5 3.9 2 1 2 4 4 4 0 Glutamic acid/alanine-rich protein of Trypanosoma RNase_H PF00075.24 KEG06232.1 - 0.0012 19.0 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF3584 PF12128.8 KEG06234.1 - 0.075 10.5 18.0 0.09 10.3 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF357 PF04010.13 KEG06234.1 - 0.16 12.1 1.6 3.1 7.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF3552 PF12072.8 KEG06234.1 - 0.35 10.3 28.2 0.42 10.0 15.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 KEG06234.1 - 0.74 9.3 12.4 0.91 9.0 12.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KEG06234.1 - 2.8 5.7 7.8 2.9 5.7 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 KEG06234.1 - 5.5 6.0 13.9 6.7 5.7 13.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ctr PF04145.15 KEG06235.1 - 0.033 14.8 0.3 0.067 13.8 0.1 1.6 2 0 0 2 2 2 0 Ctr copper transporter family DUF3450 PF11932.8 KEG06238.1 - 0.0028 17.0 3.3 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Nbl1_Borealin_N PF10444.9 KEG06238.1 - 0.0045 16.6 0.8 9.8 5.9 0.1 3.3 3 0 0 3 3 3 1 Nbl1 / Borealin N terminal DUF4407 PF14362.6 KEG06238.1 - 0.0061 15.9 7.0 0.0078 15.6 7.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DCB PF16213.5 KEG06238.1 - 1.7 8.3 4.3 11 5.7 1.6 2.7 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Uso1_p115_C PF04871.13 KEG06238.1 - 3.9 7.9 11.8 9.9 6.6 11.8 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Myotub-related PF06602.14 KEG06239.1 - 1.6e-84 283.9 0.0 2e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KEG06239.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family FYVE PF01363.21 KEG06239.1 - 0.025 14.7 12.8 0.32 11.1 12.8 2.7 1 1 0 1 1 1 0 FYVE zinc finger DSPc PF00782.20 KEG06239.1 - 0.033 14.0 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG06239.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NIF PF03031.18 KEG06241.1 - 7.4e-30 103.8 0.0 1.5e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.14 KEG06241.1 - 0.046 13.3 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Cmc1 PF08583.10 KEG06243.1 - 5.4e-06 26.3 5.4 0.0003 20.7 1.3 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 KEG06243.1 - 9.1e-06 26.0 1.0 1.2e-05 25.6 1.0 1.2 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 KEG06243.1 - 1.1e-05 25.3 0.4 2.7e-05 24.1 0.3 1.7 1 1 1 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KEG06243.1 - 0.0021 18.2 0.4 2.2 8.5 0.0 2.2 2 0 0 2 2 2 2 CHCH domain UCR_hinge PF02320.16 KEG06243.1 - 0.02 15.1 1.8 0.028 14.6 1.8 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Plus-3 PF03126.18 KEG06245.1 - 0.1 13.2 0.1 4.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Plus-3 domain K_channel_TID PF07941.11 KEG06245.1 - 0.2 12.1 4.9 9.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Sfi1 PF08457.10 KEG06246.1 - 0.00043 18.9 2.3 0.00043 18.9 2.3 4.8 2 1 2 4 4 4 2 Sfi1 spindle body protein Pkinase PF00069.25 KEG06247.1 - 8.7e-60 202.3 0.0 1.2e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06247.1 - 3e-31 108.7 0.0 4.2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06247.1 - 2e-05 24.1 0.0 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KEG06247.1 - 0.0047 16.5 0.1 0.064 12.9 0.1 2.3 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 KEG06247.1 - 0.0095 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase CBFD_NFYB_HMF PF00808.23 KEG06247.1 - 0.017 15.4 0.0 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Con-6 PF10346.9 KEG06247.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Conidiation protein 6 APH PF01636.23 KEG06247.1 - 2.9 7.7 8.8 3.3 7.6 4.9 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L12 PF00542.19 KEG06248.1 - 1.2e-17 64.0 1.3 4e-17 62.3 1.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Peripla_BP_6 PF13458.6 KEG06250.1 - 2.6e-09 37.2 4.0 6.4e-09 35.9 1.8 2.2 2 0 0 2 2 2 1 Periplasmic binding protein MtrF PF09472.10 KEG06250.1 - 0.016 14.6 1.0 0.037 13.4 1.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Bactofilin PF04519.13 KEG06251.1 - 0.038 14.3 0.0 0.048 14.0 0.0 1.1 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Nop14 PF04147.12 KEG06252.1 - 0.35 9.0 21.8 0.53 8.4 21.8 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KEG06252.1 - 2.3 6.4 19.1 3.3 5.9 19.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KEG06252.1 - 2.4 6.1 29.3 3.6 5.6 29.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 KEG06253.1 - 3.9e-37 128.2 13.0 8.2e-37 127.2 13.0 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter PRO8NT PF08082.11 KEG06254.1 - 0.04 13.9 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Malic_M PF03949.15 KEG06255.1 - 1.3e-84 283.5 0.3 1.7e-84 283.1 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KEG06255.1 - 8.5e-55 185.4 0.0 2e-54 184.1 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF4147 PF13660.6 KEG06255.1 - 0.097 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Jun PF03957.13 KEG06256.1 - 0.12 12.2 0.6 0.22 11.4 0.6 1.3 1 0 0 1 1 1 0 Jun-like transcription factor LMBR1 PF04791.16 KEG06258.1 - 9 5.1 12.1 13 4.6 12.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hexapep PF00132.24 KEG06259.1 - 9.2e-16 56.9 7.0 4.8e-06 26.1 0.1 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEG06259.1 - 0.023 14.5 2.7 0.023 14.5 2.7 2.7 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF1451 PF07295.11 KEG06259.1 - 0.14 12.2 1.2 0.82 9.7 1.7 1.8 1 1 1 2 2 2 0 Zinc-ribbon containing domain HIP1_clath_bdg PF16515.5 KEG06260.1 - 0.17 12.5 17.2 0.052 14.2 10.9 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 KEG06260.1 - 0.43 8.4 3.8 0.58 8.0 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS-augmin3 PF14932.6 KEG06260.1 - 0.78 9.3 12.1 1.3 8.6 12.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Methyltr_RsmB-F PF01189.17 KEG06262.1 - 8.3e-31 107.2 0.0 1.5e-28 99.8 0.0 3.3 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KEG06262.1 - 0.11 12.6 0.1 0.56 10.3 0.0 1.9 1 1 0 2 2 2 0 FtsJ-like methyltransferase Mem_trans PF03547.18 KEG06263.1 - 6.9e-15 54.3 20.9 8.5e-11 40.9 1.3 2.9 2 1 0 2 2 2 2 Membrane transport protein Methyltransf_11 PF08241.12 KEG06264.1 - 0.0034 18.0 0.0 0.0085 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG06264.1 - 0.0066 17.1 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG06264.1 - 0.0071 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG06264.1 - 0.021 15.6 0.0 0.043 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KEG06264.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain CoA_trans PF01144.23 KEG06265.1 - 7.7e-97 322.9 5.0 1.1e-61 208.0 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KEG06265.1 - 0.00033 20.6 0.1 0.00059 19.8 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DnaJ PF00226.31 KEG06268.1 - 7.7e-08 32.4 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Cwf_Cwc_15 PF04889.12 KEG06268.1 - 0.0025 17.6 17.0 0.0033 17.2 17.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 KEG06268.1 - 0.025 14.6 11.7 0.028 14.4 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4553 PF15090.6 KEG06268.1 - 0.05 12.6 10.2 0.066 12.2 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DUF3295 PF11702.8 KEG06268.1 - 0.099 12.0 11.1 0.13 11.6 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PPP4R2 PF09184.11 KEG06268.1 - 0.51 9.9 12.3 0.68 9.5 12.3 1.2 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 KEG06268.1 - 2.7 7.1 14.1 3.8 6.6 14.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Importin_rep_4 PF18808.1 KEG06268.1 - 7.9 6.8 9.2 15 6.0 9.2 1.4 1 0 0 1 1 1 0 Importin repeat Neur_chan_memb PF02932.16 KEG06268.1 - 8.1 6.4 6.2 10 6.1 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1168 PF06658.12 KEG06268.1 - 8.1 6.3 21.8 14 5.4 13.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) Afi1 PF07792.12 KEG06268.1 - 9.4 6.7 14.7 60 4.1 14.7 2.0 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pkinase PF00069.25 KEG06269.1 - 4.2e-50 170.6 0.0 5.4e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06269.1 - 1.3e-28 100.0 0.0 2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 KEG06269.1 - 5.8e-11 42.4 10.2 1.6e-10 41.0 10.1 1.8 1 1 0 1 1 1 1 FYVE zinc finger Pkinase_fungal PF17667.1 KEG06269.1 - 2.2e-05 23.4 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG06269.1 - 0.0009 18.6 0.0 0.0028 17.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KEG06269.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG06269.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 KEG06269.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TTL PF03133.15 KEG06270.1 - 3.6e-83 279.1 0.0 5.7e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG06270.1 - 3e-07 29.9 0.0 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KEG06270.1 - 5.4e-05 22.6 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RHSP PF07999.11 KEG06272.1 - 1.6e-29 103.1 0.0 1.7e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein RHSP PF07999.11 KEG06273.1 - 1.1e-32 113.4 0.0 1.5e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein LepB_GAP_N PF18172.1 KEG06273.1 - 0.095 12.6 1.4 0.12 12.3 0.3 1.6 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain CAF1 PF04857.20 KEG06276.1 - 4.7e-22 78.6 2.7 6.4e-11 42.0 0.1 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease gpUL132 PF11359.8 KEG06278.1 - 0.024 14.2 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 FtsJ PF01728.19 KEG06279.1 - 4.1e-65 219.2 0.0 5.4e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 KEG06280.1 - 1e-42 145.1 0.0 1.8e-41 141.1 0.0 2.4 2 1 1 3 3 3 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEG06280.1 - 0.042 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B NUDE_C PF04880.13 KEG06280.1 - 3.2 8.2 7.7 4.9 7.6 7.7 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DLIC PF05783.11 KEG06280.1 - 5.4 5.7 10.5 7.6 5.2 10.5 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MOZ_SAS PF01853.18 KEG06283.1 - 1e-40 139.3 0.0 1.4e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEG06283.1 - 0.00028 20.4 0.6 0.00049 19.6 0.6 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KEG06283.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PSP1 PF04468.12 KEG06285.1 - 7.7e-27 93.4 0.7 1.2e-26 92.8 0.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region adh_short PF00106.25 KEG06287.1 - 1e-36 126.3 0.1 1.9e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG06287.1 - 3.3e-25 89.0 0.4 4.5e-25 88.6 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG06287.1 - 3e-06 27.3 0.3 3e-06 27.3 0.3 2.0 2 1 0 2 2 2 1 KR domain HEM4 PF02602.15 KEG06287.1 - 0.00019 20.9 0.6 0.00032 20.1 0.2 1.6 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD NAD_binding_2 PF03446.15 KEG06287.1 - 0.0058 16.8 0.3 0.035 14.3 0.0 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KEG06287.1 - 0.056 12.9 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-C4H2 PF10146.9 KEG06299.1 - 0.031 14.6 2.2 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein REC114-like PF15165.6 KEG06299.1 - 0.35 10.6 2.0 0.88 9.3 0.7 2.0 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like VSP PF03302.13 KEG06301.1 - 0.033 13.1 0.2 0.062 12.1 0.2 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 KEG06301.1 - 0.056 14.3 0.0 0.096 13.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KEG06301.1 - 0.18 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Peripla_BP_6 PF13458.6 KEG06302.1 - 4.3e-11 43.1 0.9 8.4e-11 42.1 0.9 1.4 1 0 0 1 1 1 1 Periplasmic binding protein ParD PF09386.10 KEG06302.1 - 0.17 12.3 1.9 5.9 7.4 0.3 2.5 2 0 0 2 2 2 0 Antitoxin ParD DUF4235 PF14019.6 KEG06302.1 - 5.5 7.2 11.2 1.1 9.4 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Shisa PF13908.6 KEG06303.1 - 0.022 15.0 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator S1-P1_nuclease PF02265.16 KEG06304.1 - 2.4e-54 184.8 0.0 2.9e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease NNMT_PNMT_TEMT PF01234.17 KEG06304.1 - 0.095 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family IF4E PF01652.18 KEG06305.1 - 6e-29 100.9 0.0 7.6e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PAM2 PF07145.15 KEG06305.1 - 0.0095 15.6 3.3 0.21 11.3 0.1 3.1 3 0 0 3 3 3 1 Ataxin-2 C-terminal region Spc42p PF11544.8 KEG06305.1 - 0.4 10.7 1.8 0.38 10.8 0.1 1.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p SPX PF03105.19 KEG06305.1 - 7.6 6.3 8.6 11 5.8 8.6 1.3 1 0 0 1 1 1 0 SPX domain PPR_3 PF13812.6 KEG06309.1 - 4.1e-09 36.4 0.0 0.019 15.1 0.0 3.9 1 1 3 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 KEG06309.1 - 1.3e-05 25.3 0.0 0.14 12.3 0.0 3.3 2 1 2 4 4 4 2 PPR repeat family PPR_long PF17177.4 KEG06309.1 - 0.00013 21.4 0.1 0.073 12.4 0.0 2.3 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KEG06309.1 - 0.00078 19.5 0.0 22 5.6 0.0 4.4 5 0 0 5 5 5 1 PPR repeat TPR_MalT PF17874.1 KEG06309.1 - 0.055 12.8 2.3 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 MalT-like TPR region DUF5339 PF17274.2 KEG06312.1 - 0.032 15.1 3.7 0.043 14.7 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5339) TetR_C_2 PF08361.11 KEG06312.1 - 0.069 13.3 0.1 0.077 13.1 0.1 1.1 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Peptidase_M8 PF01457.16 KEG06314.1 - 6.1e-57 193.5 6.7 7.3e-57 193.2 6.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Prefoldin PF02996.17 KEG06317.1 - 7.9e-20 71.0 0.2 1.1e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Exo_endo_phos_2 PF14529.6 KEG06318.1 - 0.063 13.1 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase GST_N PF02798.20 KEG06319.1 - 7.2e-13 48.7 0.0 1.6e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEG06319.1 - 2.2e-08 34.4 0.0 5.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEG06319.1 - 2.5e-05 24.4 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEG06319.1 - 2.8e-05 24.3 0.0 6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEG06319.1 - 0.0001 22.6 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEG06319.1 - 0.097 12.7 0.2 0.22 11.6 0.2 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NOT2_3_5 PF04153.18 KEG06320.1 - 2e-18 66.7 0.5 2e-18 66.7 0.5 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family TFIIA PF03153.13 KEG06320.1 - 0.0063 16.6 11.7 0.0063 16.6 11.7 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KEG06320.1 - 0.85 9.2 18.3 1.7 8.2 18.3 1.6 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 KEG06320.1 - 2.9 7.8 7.5 5.4 6.9 7.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PRKCSH-like PF12999.7 KEG06321.1 - 1.4e-40 138.9 5.1 1.4e-40 138.9 5.1 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KEG06321.1 - 2.9e-23 82.3 0.7 9.7e-23 80.6 0.7 2.0 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KEG06321.1 - 3.6e-08 34.3 2.1 3.6e-08 34.3 2.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein GldM_N PF12081.8 KEG06321.1 - 0.0097 16.0 0.7 0.026 14.6 0.0 1.9 2 0 0 2 2 2 1 GldM N-terminal domain DUF4407 PF14362.6 KEG06321.1 - 0.15 11.4 7.6 6 6.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KEG06321.1 - 3.8 7.8 11.6 0.43 10.8 0.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nup88 PF10168.9 KEG06321.1 - 6.7 4.4 9.3 9.7 3.9 4.9 2.0 2 0 0 2 2 2 0 Nuclear pore component DUF3450 PF11932.8 KEG06321.1 - 9.8 5.4 8.4 6.4 6.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Vinculin PF01044.19 KEG06322.1 - 0.1 10.8 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Vinculin family DUF4506 PF14958.6 KEG06323.1 - 0.0077 15.8 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4506) MRP-L46 PF11788.8 KEG06324.1 - 1.1e-14 55.2 0.2 3.2e-14 53.7 0.0 1.9 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 VIGSSK PF14773.6 KEG06325.1 - 0.14 12.3 0.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal OS-D PF03392.13 KEG06325.1 - 0.15 12.2 0.0 53 4.0 0.0 3.3 2 1 1 3 3 3 0 Insect pheromone-binding family, A10/OS-D Acyl-CoA_dh_C PF12806.7 KEG06326.1 - 2.3e-21 76.2 0.1 5e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 KEG06326.1 - 3.6e-20 72.7 1.4 2.2e-19 70.2 1.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEG06326.1 - 5.8e-18 64.9 0.0 1.2e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEG06326.1 - 3.6e-15 56.6 0.0 8.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEG06326.1 - 1.6e-05 25.2 0.0 3.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 KEG06326.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal RBB1NT PF08169.11 KEG06327.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Mucin PF01456.17 KEG06328.1 - 0.039 13.9 31.1 0.077 13.0 5.9 3.8 1 1 1 2 2 2 0 Mucin-like glycoprotein PsaD PF02531.16 KEG06328.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 PsaD LSM PF01423.22 KEG06330.1 - 1.3e-11 44.0 0.1 1.5e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain DinB PF05163.12 KEG06334.1 - 0.098 12.6 0.1 0.14 12.1 0.1 1.2 1 1 0 1 1 1 0 DinB family Ras PF00071.22 KEG06336.1 - 1.8e-63 213.0 0.3 2e-63 212.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG06336.1 - 3.7e-36 124.0 0.1 6.5e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG06336.1 - 1e-15 57.6 0.1 1.1e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEG06336.1 - 4.8e-06 26.6 0.4 0.075 12.9 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KEG06336.1 - 3.4e-05 23.3 0.1 4.1e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEG06336.1 - 7.1e-05 22.3 0.1 8.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEG06336.1 - 0.00024 21.1 0.0 0.00054 20.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG06336.1 - 0.00056 19.5 0.3 0.0011 18.5 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KEG06336.1 - 0.003 17.1 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 KEG06336.1 - 0.0093 16.4 0.0 0.56 10.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG06336.1 - 0.029 14.8 0.0 0.039 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEG06336.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEG06336.1 - 0.07 13.6 0.1 0.19 12.2 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KEG06336.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KEG06336.1 - 0.082 13.2 0.0 0.23 11.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KEG06336.1 - 0.15 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein V-SNARE_C PF12352.8 KEG06337.1 - 6.8e-06 26.3 1.6 1.2e-05 25.4 1.6 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus S4 PF01479.25 KEG06338.1 - 3.5e-12 45.8 0.2 7.7e-12 44.7 0.2 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KEG06338.1 - 6.3e-07 30.2 0.2 1.4e-06 29.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain ELYS-bb PF16687.5 KEG06339.1 - 0.17 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin FAD-oxidase_C PF02913.19 KEG06340.1 - 4.3e-45 154.3 0.0 5.9e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEG06340.1 - 2.2e-33 114.9 0.5 4e-33 114.1 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Peripla_BP_6 PF13458.6 KEG06344.1 - 1.9e-12 47.6 1.8 2.6e-12 47.1 1.8 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF5356 PF17309.2 KEG06344.1 - 0.24 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5356) GARP PF16731.5 KEG06346.1 - 0.0053 16.5 43.4 0.03 14.0 6.8 2.9 3 0 0 3 3 3 2 Glutamic acid/alanine-rich protein of Trypanosoma Atg14 PF10186.9 KEG06346.1 - 0.085 11.9 5.2 0.13 11.4 5.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KEG06346.1 - 0.68 9.9 20.0 1.9 8.5 5.8 3.3 2 1 1 3 3 3 0 Laminin Domain II MIF4G PF02854.19 KEG06347.1 - 7.6e-15 55.1 1.3 4.1e-14 52.7 0.4 2.2 2 0 0 2 2 2 1 MIF4G domain V-SNARE PF05008.15 KEG06347.1 - 0.0042 17.4 0.4 0.014 15.7 0.4 1.9 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus TFIIA PF03153.13 KEG06347.1 - 6.7 6.6 8.8 0.63 10.0 4.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nod1 PF17114.5 KEG06348.1 - 0.072 13.3 0.2 0.095 12.9 0.2 1.2 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DSPc PF00782.20 KEG06352.1 - 5.5e-31 107.1 0.0 9e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG06352.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thioredoxin PF00085.20 KEG06353.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KEG06353.1 - 2.8e-06 26.5 0.2 4.1e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Phosducin VKOR PF07884.14 KEG06354.1 - 4.4e-16 59.2 15.7 5.5e-16 58.9 15.7 1.0 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Cyclin PF08613.11 KEG06355.1 - 4.3e-22 79.2 0.1 7.1e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEG06355.1 - 8.1e-05 22.4 0.1 0.00016 21.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_M14 PF00246.24 KEG06357.1 - 0.01 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase Mucin PF01456.17 KEG06358.1 - 0.0039 17.2 9.5 0.0039 17.2 9.5 3.0 3 1 0 3 3 3 2 Mucin-like glycoprotein Pinin_SDK_N PF04697.13 KEG06359.1 - 2.7 8.6 9.7 0.071 13.8 1.0 2.9 3 0 0 3 3 3 0 pinin/SDK conserved region Costars PF14705.6 KEG06360.1 - 3.3e-05 24.0 0.0 5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Costars AMP-binding PF00501.28 KEG06361.1 - 3.9e-88 295.9 0.0 5.7e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BT1 PF03092.16 KEG06362.1 - 1.1e-48 165.8 1.4 1.3e-48 165.5 1.4 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 KEG06362.1 - 0.033 13.1 0.4 0.039 12.9 0.4 1.2 1 1 0 1 1 1 0 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 KEG06363.1 - 1.4e-19 70.5 28.8 7e-19 68.1 26.1 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF4162 PF13732.6 KEG06364.1 - 0.034 14.8 0.0 0.054 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Aa_trans PF01490.18 KEG06370.1 - 2.4e-46 158.2 19.5 2.8e-46 158.0 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG06370.1 - 3.9e-11 42.6 7.1 3.9e-11 42.6 7.1 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Cation_ATPase_C PF00689.21 KEG06370.1 - 6.2 6.5 14.1 0.67 9.6 4.6 2.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Chromo PF00385.24 KEG06372.1 - 1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KEG06372.1 - 0.026 14.7 0.1 0.063 13.5 0.1 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 CRT-like PF08627.10 KEG06374.1 - 1.3e-10 40.7 10.9 2.7e-10 39.7 10.9 1.6 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KEG06374.1 - 5.5e-10 38.9 9.9 1.1e-09 38.0 1.2 2.3 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.20 KEG06374.1 - 1.8e-08 34.6 20.6 0.00011 22.4 9.0 3.4 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KEG06374.1 - 1.8e-06 27.3 2.2 1.8e-06 27.3 2.2 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter SLC35F PF06027.12 KEG06374.1 - 3.5e-06 26.7 1.6 3.5e-06 26.7 1.6 2.3 2 1 0 2 2 2 2 Solute carrier family 35 TMEM234 PF10639.9 KEG06374.1 - 0.00032 20.7 0.6 0.00032 20.7 0.6 1.9 2 0 0 2 2 2 1 Putative transmembrane family 234 PUNUT PF16913.5 KEG06374.1 - 0.00096 18.5 1.2 0.00096 18.5 1.2 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF872 PF05915.12 KEG06374.1 - 0.0017 18.5 0.4 3.2 7.9 0.0 2.7 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF872) Pkinase PF00069.25 KEG06376.1 - 6.2e-62 209.4 0.0 8.6e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06376.1 - 3.1e-47 161.0 0.0 5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06376.1 - 5.3e-05 22.7 0.1 0.00026 20.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEG06376.1 - 0.0011 18.9 1.4 1.6 8.6 0.0 2.9 3 0 0 3 3 3 2 Phosphotransferase enzyme family GFA PF04828.14 KEG06376.1 - 0.061 13.7 0.2 19 5.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme BAF1_ABF1 PF04684.13 KEG06376.1 - 0.52 9.3 5.7 0.81 8.7 5.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_2 PF13639.6 KEG06377.1 - 3e-09 37.0 10.4 5.8e-09 36.1 10.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEG06377.1 - 0.00045 20.0 7.6 0.00073 19.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEG06377.1 - 0.0031 17.2 6.9 0.0031 17.2 6.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KEG06377.1 - 0.01 15.8 9.8 0.019 14.9 9.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEG06377.1 - 0.012 15.4 11.3 0.021 14.6 10.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEG06377.1 - 0.014 15.7 8.0 0.046 14.0 8.0 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KEG06377.1 - 0.2 11.3 7.8 0.36 10.5 7.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KEG06377.1 - 0.44 10.4 8.4 0.86 9.5 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_10 PF10058.9 KEG06377.1 - 0.61 9.9 5.1 1.2 8.9 5.1 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Thioredoxin PF00085.20 KEG06380.1 - 2.8e-15 56.2 0.0 7.4e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEG06380.1 - 0.0035 17.8 0.1 0.066 13.7 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEG06380.1 - 0.0091 16.3 0.2 1.5 9.2 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like Pkinase PF00069.25 KEG06383.1 - 1.4e-44 152.5 0.0 6.7e-43 146.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06383.1 - 2.3e-24 86.1 0.0 3e-23 82.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KEG06383.1 - 0.0021 17.4 0.0 0.0053 16.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3603 PF12227.8 KEG06386.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Glutaredoxin PF00462.24 KEG06387.1 - 4.7e-17 61.9 0.1 8.5e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 KEG06387.1 - 3.4e-13 49.5 0.0 9.8e-13 48.0 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin TTRAP PF14203.6 KEG06387.1 - 0.0015 18.4 0.0 0.0045 16.9 0.0 1.8 2 0 0 2 2 2 1 Putative tranposon-transfer assisting protein AhpC-TSA PF00578.21 KEG06387.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 KEG06387.1 - 0.015 15.6 0.0 0.047 14.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like AAA PF00004.29 KEG06388.1 - 3.5e-37 127.8 0.0 6.2e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG06388.1 - 7.3e-09 35.3 0.0 1.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEG06388.1 - 9.7e-08 31.9 0.0 1.9e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEG06388.1 - 1.7e-06 28.1 0.0 9.6e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG06388.1 - 1.9e-06 28.3 0.1 5.5e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KEG06388.1 - 6.5e-06 25.6 0.0 1.9e-05 24.0 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 KEG06388.1 - 2.6e-05 24.8 0.0 6.6e-05 23.5 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KEG06388.1 - 2.8e-05 24.4 0.2 0.00062 20.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEG06388.1 - 6.4e-05 23.1 0.0 0.00015 22.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KEG06388.1 - 0.00014 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KEG06388.1 - 0.00028 20.9 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KEG06388.1 - 0.00055 20.1 0.0 0.0029 17.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KEG06388.1 - 0.0006 20.2 0.0 0.0021 18.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KEG06388.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KEG06388.1 - 0.0033 17.3 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KEG06388.1 - 0.0036 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KEG06388.1 - 0.0037 17.0 0.0 0.0077 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEG06388.1 - 0.0041 17.4 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEG06388.1 - 0.0059 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KEG06388.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 KEG06388.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Parvo_NS1 PF01057.17 KEG06388.1 - 0.0094 15.1 0.0 0.054 12.6 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 SKI PF01202.22 KEG06388.1 - 0.014 15.6 0.1 0.032 14.4 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase NACHT PF05729.12 KEG06388.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KEG06388.1 - 0.024 14.2 0.4 0.14 11.7 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEG06388.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 KEG06388.1 - 0.042 14.0 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KEG06388.1 - 0.045 13.5 0.0 0.16 11.7 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KEG06388.1 - 0.049 14.1 0.2 0.12 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.18 KEG06388.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein Cytidylate_kin PF02224.18 KEG06388.1 - 0.057 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase PhoH PF02562.16 KEG06388.1 - 0.063 12.7 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KEG06388.1 - 0.072 12.9 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 KEG06388.1 - 0.11 11.9 0.0 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Isopentenyl transferase Vps4_C PF09336.10 KEG06388.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain TniB PF05621.11 KEG06388.1 - 0.16 11.4 0.0 11 5.4 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 KEG06388.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PPV_E1_C PF00519.17 KEG06388.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_30 PF13604.6 KEG06388.1 - 0.24 11.1 0.1 0.49 10.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Cation_ATPase_C PF00689.21 KEG06389.1 - 4e-34 117.9 0.4 5e-34 117.6 0.4 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus PhrC_PhrF PF11131.8 KEG06389.1 - 7.1e-05 22.3 0.1 0.00015 21.3 0.1 1.6 1 0 0 1 1 1 1 Rap-phr extracellular signalling DPRP PF04244.13 KEG06389.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DUF4250 PF14056.6 KEG06390.1 - 0.0067 16.4 3.3 0.44 10.5 0.3 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4250) JAB PF01398.21 KEG06390.1 - 0.0078 16.2 0.0 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RVT_1 PF00078.27 KEG06395.1 - 0.035 13.6 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KEG06396.1 - 2.4e-60 204.1 0.0 3.2e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06396.1 - 2.5e-40 138.4 0.0 3.3e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06396.1 - 7.6e-09 35.3 0.0 2.5e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 KEG06396.1 - 0.0014 19.1 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 KEG06396.1 - 0.022 13.7 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KEG06396.1 - 0.065 12.2 0.1 0.094 11.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PH_9 PF15410.6 KEG06396.1 - 0.18 12.2 0.6 1.3 9.4 0.6 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Mucin PF01456.17 KEG06397.1 - 7.2 6.6 21.6 0.32 11.0 15.3 2.0 2 1 0 2 2 2 0 Mucin-like glycoprotein Mucin PF01456.17 KEG06399.1 - 0.0011 19.0 6.6 0.0014 18.6 6.6 1.4 1 1 0 1 1 1 1 Mucin-like glycoprotein Arm PF00514.23 KEG06401.1 - 0.0026 17.7 0.1 1.7 8.8 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Nsp3_PL2pro PF12124.8 KEG06401.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Peptidase_M8 PF01457.16 KEG06404.1 - 1.6e-09 37.0 0.8 2.3e-09 36.5 0.8 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 KEG06405.1 - 4.3e-19 68.6 1.4 4.4e-19 68.6 1.4 1.1 1 0 0 1 1 1 1 Leishmanolysin Orthopox_35kD PF02250.15 KEG06405.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 35kD major secreted virus protein UPF0242 PF06785.11 KEG06406.1 - 0.0095 16.1 1.1 0.0095 16.1 1.1 2.5 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Sporozoite_P67 PF05642.11 KEG06410.1 - 0.7 7.9 10.7 0.093 10.8 1.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen HofP PF10748.9 KEG06411.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 DNA utilization proteins HofP DUF4357 PF14267.6 KEG06411.1 - 5.2 7.1 6.1 5.2 7.1 4.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4357) BMFP PF04380.13 KEG06412.1 - 0.042 14.3 0.4 0.084 13.4 0.1 1.8 2 1 0 2 2 2 0 Membrane fusogenic activity LRR_4 PF12799.7 KEG06413.1 - 1.1e-06 28.9 0.1 0.0025 18.2 0.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG06413.1 - 2.5e-05 24.0 0.8 5.3e-05 22.9 0.2 1.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 KEG06413.1 - 0.00041 19.9 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KEG06413.1 - 0.33 11.1 2.9 20 5.5 0.2 2.9 2 0 0 2 2 2 0 Leucine Rich repeat SpoIIE PF07228.12 KEG06416.1 - 7.3e-07 29.3 0.3 1.6e-05 24.9 0.3 2.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEG06416.1 - 0.00027 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KEG06416.1 - 0.12 12.0 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C mTERF PF02536.14 KEG06418.1 - 8.4e-05 21.6 0.0 0.00015 20.8 0.0 1.4 1 1 0 1 1 1 1 mTERF Slu7 PF11708.8 KEG06419.1 - 4.8e-05 23.2 2.1 7.2e-05 22.7 0.1 2.1 2 1 1 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KEG06419.1 - 0.28 11.0 1.4 0.77 9.5 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle Amidohydro_1 PF01979.20 KEG06420.1 - 1.9e-19 70.2 0.0 2.3e-13 50.2 0.0 2.1 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KEG06420.1 - 1.9e-18 67.2 4.9 4.9e-13 49.4 0.5 2.8 1 1 0 2 2 2 2 Amidohydrolase family Alk_phosphatase PF00245.20 KEG06420.1 - 0.059 12.3 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase CwsA PF10814.8 KEG06421.1 - 0.0091 16.2 2.0 0.018 15.2 2.0 1.5 1 0 0 1 1 1 1 Cell wall synthesis protein CwsA ADK PF00406.22 KEG06422.1 - 8.7e-51 172.0 0.0 1.1e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEG06422.1 - 2.5e-20 73.3 0.0 4.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KEG06422.1 - 1.4e-16 60.1 0.1 7.2e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 KEG06422.1 - 0.00041 20.7 0.0 0.011 16.0 0.0 2.2 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 KEG06422.1 - 0.00043 20.8 0.0 0.0009 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG06422.1 - 0.01 16.0 0.2 0.033 14.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEG06422.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Herpes_UL52 PF03121.15 KEG06423.1 - 0.26 11.3 1.5 0.71 9.9 1.5 1.7 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Mucin PF01456.17 KEG06424.1 - 6.7e-07 29.4 65.3 2.2e-05 24.5 18.2 4.2 1 1 3 4 4 4 3 Mucin-like glycoprotein DUF3450 PF11932.8 KEG06425.1 - 0.00069 19.0 2.5 0.00069 19.0 2.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Laminin_II PF06009.12 KEG06425.1 - 0.1 12.6 9.9 0.25 11.3 2.9 2.1 2 0 0 2 2 2 0 Laminin Domain II CENP-K PF11802.8 KEG06425.1 - 0.13 11.8 1.6 0.2 11.2 1.6 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF1664 PF07889.12 KEG06425.1 - 0.15 12.1 4.5 3 7.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SecD-TM1 PF13721.6 KEG06425.1 - 0.23 11.9 3.0 0.83 10.1 0.5 2.1 2 0 0 2 2 2 0 SecD export protein N-terminal TM region HAUS-augmin3 PF14932.6 KEG06425.1 - 0.42 10.2 8.6 0.12 11.9 1.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_TATA_bd PF12325.8 KEG06425.1 - 0.45 10.8 5.9 0.26 11.5 0.8 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 KEG06425.1 - 0.59 10.4 10.5 0.6 10.4 1.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Goodbye PF17109.5 KEG06425.1 - 0.63 10.5 5.1 0.38 11.2 2.4 1.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Mucin PF01456.17 KEG06425.1 - 0.79 9.7 9.5 1.7 8.6 9.5 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein CREPT PF16566.5 KEG06425.1 - 0.82 9.8 7.2 0.43 10.8 1.2 2.2 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour OmpH PF03938.14 KEG06425.1 - 1.6 9.1 11.0 0.24 11.7 4.3 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4936 PF16290.5 KEG06425.1 - 3 8.6 5.8 1 10.1 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4936) M16C_assoc PF08367.11 KEG06426.1 - 0.00012 21.3 2.6 0.00021 20.5 2.6 1.4 1 0 0 1 1 1 1 Peptidase M16C associated HisKA_3 PF07730.13 KEG06426.1 - 0.15 12.6 6.0 0.26 11.8 3.5 2.4 2 1 0 2 2 2 0 Histidine kinase TMPIT PF07851.13 KEG06426.1 - 0.16 11.2 0.3 0.23 10.7 0.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1682 PF07946.14 KEG06426.1 - 0.3 10.2 6.6 0.37 10.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mucin PF01456.17 KEG06426.1 - 2.7 8.0 10.2 0.58 10.1 3.2 2.7 2 1 0 2 2 2 0 Mucin-like glycoprotein OmpH PF03938.14 KEG06426.1 - 3 8.2 11.1 1.3 9.4 7.5 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) P4Ha_N PF08336.11 KEG06430.1 - 0.17 11.9 5.7 0.12 12.4 0.5 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Sec34 PF04136.15 KEG06430.1 - 0.83 9.5 10.1 2.3 8.1 1.0 3.1 3 1 1 4 4 4 0 Sec34-like family Mucin PF01456.17 KEG06431.1 - 0.0046 17.0 3.0 0.0049 16.9 3.0 1.3 1 1 0 1 1 1 1 Mucin-like glycoprotein TerB PF05099.13 KEG06431.1 - 0.03 14.3 5.4 0.032 14.2 4.8 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TerB PSD5 PF07637.11 KEG06431.1 - 0.057 13.8 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) XhlA PF10779.9 KEG06432.1 - 0.054 13.7 0.3 0.054 13.7 0.3 3.9 2 1 2 4 4 4 0 Haemolysin XhlA Hydrolase_6 PF13344.6 KEG06432.1 - 0.16 12.1 1.2 0.57 10.3 0.0 2.5 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Caldesmon PF02029.15 KEG06432.1 - 0.32 9.7 30.6 0.43 9.3 30.6 1.2 1 0 0 1 1 1 0 Caldesmon DUF5446 PF17522.2 KEG06432.1 - 2.2 8.5 8.0 7.5 6.8 3.9 3.3 1 1 1 2 2 2 0 Family of unknown function (DUF5446) GREB1 PF15782.5 KEG06432.1 - 3.3 4.7 15.4 3.9 4.5 15.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HisKA_3 PF07730.13 KEG06432.1 - 7.8 7.1 19.8 1.1 9.9 3.5 4.5 2 2 1 3 3 3 0 Histidine kinase Kinesin PF00225.23 KEG06433.1 - 4.1e-35 121.3 0.0 4.8e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG06433.1 - 1.7e-10 41.0 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Ribosomal_L22 PF00237.19 KEG06434.1 - 1.9e-32 111.5 0.1 2.3e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.13 KEG06435.1 - 0.00073 20.0 0.1 0.0012 19.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.26 KEG06435.1 - 0.13 12.4 0.3 0.31 11.2 0.2 1.7 2 0 0 2 2 2 0 WW domain Vault PF01505.18 KEG06436.1 - 1.8e-42 143.2 0.4 8e-12 45.1 0.0 4.8 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 KEG06436.1 - 1.8e-42 144.1 0.0 3.3e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 KEG06436.1 - 4.7e-28 97.0 0.1 3.4e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 KEG06436.1 - 6.5e-15 54.9 0.0 2.3e-13 50.0 0.0 3.4 4 0 0 4 4 4 1 Major Vault Protein repeat domain Vault_2 PF17794.1 KEG06436.1 - 4.2e-13 49.5 7.1 7e-08 32.7 1.4 3.3 2 2 0 2 2 2 2 Major Vault Protein repeat domain Band_7 PF01145.25 KEG06436.1 - 0.00091 19.3 0.0 0.046 13.7 0.0 2.6 1 1 0 2 2 2 1 SPFH domain / Band 7 family DUF3740 PF12548.8 KEG06438.1 - 0.11 12.9 7.3 0.14 12.6 0.7 2.7 2 1 0 2 2 2 0 Sulfatase protein GARP PF16731.5 KEG06438.1 - 0.15 11.7 45.2 0.16 11.6 7.0 3.2 3 0 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Hrs_helical PF12210.8 KEG06438.1 - 0.59 10.7 5.4 27 5.4 0.4 3.5 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Mucin PF01456.17 KEG06440.1 - 0.0011 19.0 9.8 0.0011 19.0 9.8 2.8 2 1 0 2 2 2 1 Mucin-like glycoprotein FANCM-MHF_bd PF16783.5 KEG06445.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 FANCM to MHF binding domain Pkinase PF00069.25 KEG06449.1 - 1.4e-24 86.9 0.0 2.1e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06449.1 - 5.3e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG06449.1 - 0.04 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEG06449.1 - 0.11 11.8 0.1 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.28 KEG06455.1 - 2.4e-11 44.3 0.1 2.6e-10 41.0 0.1 2.0 1 1 0 1 1 1 1 SET domain PMP1_2 PF08114.11 KEG06455.1 - 0.033 13.9 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Torus PF16131.5 KEG06456.1 - 5.6e-07 30.2 0.1 9.8e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KEG06456.1 - 5.8e-06 26.2 3.6 8.8e-06 25.6 3.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEG06456.1 - 1.7e-05 24.5 0.6 2.5e-05 24.0 0.6 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KEG06456.1 - 8.4e-05 22.4 0.6 0.00013 21.7 0.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KEG06456.1 - 0.005 17.3 0.4 0.0074 16.7 0.4 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger GRP PF07172.11 KEG06460.1 - 3.4 8.4 15.5 6.9 7.4 15.5 1.5 1 0 0 1 1 1 0 Glycine rich protein family RAM PF15320.6 KEG06460.1 - 3.7 8.2 14.9 5.4 7.7 5.0 2.2 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein DEAD PF00270.29 KEG06462.1 - 1.9e-46 158.0 0.0 2e-45 154.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG06462.1 - 2.1e-27 95.7 0.0 7.4e-26 90.7 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG06462.1 - 2.8e-05 24.2 0.0 0.003 17.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KEG06462.1 - 0.087 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KEG06462.1 - 0.31 11.3 2.5 1.6 9.0 0.9 2.7 2 1 0 2 2 2 0 AAA domain PSRT PF07636.11 KEG06464.1 - 1.5 8.5 8.2 0.93 9.2 3.3 2.3 2 0 0 2 2 2 0 PSRT Sec1 PF00995.23 KEG06465.1 - 3.5e-95 320.4 0.0 3.9e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CLP1_P PF16575.5 KEG06466.1 - 3.9e-11 43.1 0.0 8.5e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KEG06466.1 - 3.1e-08 33.7 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor DUF5545 PF17699.1 KEG06466.1 - 0.029 14.2 0.0 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5545) AAA_lid_11 PF18198.1 KEG06469.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain TPR_1 PF00515.28 KEG06472.1 - 2.6e-14 52.3 8.1 3.8e-07 29.7 1.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG06472.1 - 8.2e-12 44.3 6.7 5.4e-06 26.1 1.5 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG06472.1 - 2.5e-09 36.6 1.5 0.00025 20.7 0.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KEG06472.1 - 3.6e-05 23.6 7.3 0.00024 21.1 0.7 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG06472.1 - 7.5e-05 22.9 2.6 0.058 13.7 0.8 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEG06472.1 - 0.00089 19.9 15.9 0.0038 17.8 2.7 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG06472.1 - 0.0012 19.5 5.1 0.15 13.0 1.2 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG06472.1 - 0.0075 16.2 2.1 1.2 9.4 0.7 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG06472.1 - 0.012 16.2 3.3 0.025 15.2 1.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG06472.1 - 0.019 15.4 3.9 0.07 13.7 3.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NST1 PF13945.6 KEG06472.1 - 0.027 14.6 0.8 0.04 14.0 0.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator MIT PF04212.18 KEG06472.1 - 1.9 8.6 6.9 16 5.7 0.4 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KEG06472.1 - 7.6 6.6 6.1 1.5 8.8 0.6 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 KEG06473.1 - 0.21 11.1 0.0 0.66 9.4 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 KEG06475.1 - 2.3e-22 80.5 0.0 4.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUIM_assoc PF16619.5 KEG06475.1 - 0.0037 17.3 0.4 0.0082 16.2 0.4 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CHORD PF04968.12 KEG06478.1 - 4.3e-43 145.9 20.9 1.4e-21 76.9 4.7 2.3 2 0 0 2 2 2 2 CHORD Ribosomal_S17_N PF16205.5 KEG06479.1 - 4.7e-30 103.8 0.2 9.2e-30 102.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KEG06479.1 - 3.3e-22 78.4 0.2 6.6e-22 77.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 DUF5075 PF16825.5 KEG06480.1 - 4.3e-49 166.5 0.0 6.1e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 IGP family C-type lectin domain Shisa PF13908.6 KEG06480.1 - 0.00012 22.4 0.2 0.00026 21.3 0.2 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Fungal_trans_2 PF11951.8 KEG06480.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Tetraspanin PF00335.20 KEG06480.1 - 0.16 11.7 3.6 0.09 12.5 1.4 1.6 2 0 0 2 2 2 0 Tetraspanin family Mucin PF01456.17 KEG06480.1 - 3.3 7.7 9.0 0.14 12.1 2.9 2.0 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF5075 PF16825.5 KEG06481.1 - 7.6e-37 126.7 0.0 1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 IGP family C-type lectin domain Shisa PF13908.6 KEG06481.1 - 0.0054 17.0 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM52 PF14979.6 KEG06481.1 - 0.018 15.0 2.5 0.029 14.3 2.5 1.3 1 0 0 1 1 1 0 Transmembrane 52 Prominin PF05478.11 KEG06481.1 - 0.17 9.8 3.6 0.21 9.5 3.6 1.1 1 0 0 1 1 1 0 Prominin SCIMP PF15050.6 KEG06481.1 - 0.34 11.4 1.7 0.7 10.4 1.7 1.5 1 0 0 1 1 1 0 SCIMP protein UPF0370 PF13980.6 KEG06481.1 - 7.3 6.7 9.3 0.65 10.1 4.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) BDV_P10 PF06515.11 KEG06482.1 - 0.05 13.6 4.4 0.093 12.8 1.6 2.5 2 0 0 2 2 2 0 Borna disease virus P10 protein Mucin PF01456.17 KEG06482.1 - 0.36 10.8 18.6 1.8 8.6 18.2 2.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Mucin PF01456.17 KEG06483.1 - 0.00083 19.4 3.4 0.00083 19.4 3.4 4.0 3 1 0 3 3 3 1 Mucin-like glycoprotein LST1 PF05083.13 KEG06484.1 - 0.084 13.2 0.4 0.13 12.6 0.1 1.5 2 0 0 2 2 2 0 LST-1 protein Spore_SspJ PF09575.10 KEG06485.1 - 0.11 13.0 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) DivIC PF04977.15 KEG06486.1 - 0.025 14.4 4.9 0.025 14.4 4.9 2.0 1 1 1 2 2 2 0 Septum formation initiator LPP PF04728.13 KEG06486.1 - 0.046 14.1 2.7 0.046 14.1 2.7 1.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1465 PF07323.12 KEG06486.1 - 0.05 13.5 3.6 0.096 12.5 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) CLZ PF16526.5 KEG06486.1 - 0.055 13.8 3.9 0.078 13.3 3.7 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspB PF06667.12 KEG06486.1 - 0.092 12.8 2.2 6.7 6.8 0.4 2.2 1 1 1 2 2 2 0 Phage shock protein B XhlA PF10779.9 KEG06486.1 - 0.096 12.9 0.4 0.16 12.2 0.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.18 KEG06486.1 - 0.39 11.1 4.8 0.22 11.8 1.5 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 KEG06486.1 - 0.97 9.9 13.2 0.17 12.4 5.7 2.0 1 1 1 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 KEG06486.1 - 1.3 8.9 12.6 0.4 10.6 8.0 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 KEG06486.1 - 1.5 9.0 11.5 1.2 9.3 5.8 2.4 2 1 0 2 2 2 0 Basic region leucine zipper PGK PF00162.19 KEG06488.1 - 1.1e-55 189.2 0.1 1.1e-54 185.8 0.1 1.9 1 1 0 1 1 1 1 Phosphoglycerate kinase PEPcase PF00311.17 KEG06488.1 - 0.045 11.8 0.0 0.063 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase AAA_16 PF13191.6 KEG06489.1 - 1e-06 29.3 2.7 6.9e-06 26.5 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.6 KEG06489.1 - 0.00095 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEG06489.1 - 0.0038 17.2 0.0 0.27 11.1 0.0 2.7 1 1 1 2 2 2 1 NACHT domain NB-ARC PF00931.22 KEG06489.1 - 0.0083 15.3 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEG06489.1 - 0.013 15.7 0.1 0.076 13.3 0.0 2.2 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 KEG06489.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KEG06489.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEG06489.1 - 0.14 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEG06489.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KEG06489.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KEG06489.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 NTPase LRR_8 PF13855.6 KEG06491.1 - 9.8e-22 76.5 13.7 4.1e-06 26.4 0.1 5.0 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KEG06491.1 - 2.6e-18 65.8 9.3 0.02 15.3 0.2 7.2 5 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG06491.1 - 0.002 17.7 1.0 0.25 10.8 0.1 3.5 3 1 0 4 4 4 1 Leucine-rich repeat LRR_6 PF13516.6 KEG06491.1 - 0.37 11.0 16.0 2.4 8.4 0.1 7.6 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 KEG06491.1 - 0.6 10.9 27.2 3.1 8.7 0.1 10.5 12 1 0 12 12 12 0 Leucine Rich Repeat GRDP-like PF07173.12 KEG06491.1 - 5.5 7.6 5.6 54 4.4 0.1 3.7 3 1 1 4 4 4 0 Glycine-rich domain-containing protein-like Cyclin_N PF00134.23 KEG06492.1 - 0.00011 21.9 0.1 0.00019 21.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SWC7 PF17330.2 KEG06492.1 - 0.042 13.9 0.2 0.088 12.9 0.2 1.4 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 zf-CCCH PF00642.24 KEG06498.1 - 1.7e-06 27.8 1.5 2.8e-06 27.1 1.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG06498.1 - 1e-05 25.4 4.6 1.7e-05 24.7 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEG06498.1 - 1.2e-05 25.0 2.1 1.9e-05 24.3 2.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KEG06498.1 - 0.00087 20.0 1.3 0.0018 18.9 1.3 1.5 1 1 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KEG06498.1 - 0.0089 16.5 1.2 0.016 15.7 1.2 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger RL PF17797.1 KEG06499.1 - 0.0022 17.9 0.1 0.0092 15.9 0.1 2.0 2 0 0 2 2 2 1 RL domain Pinin_SDK_N PF04697.13 KEG06499.1 - 4 8.1 6.2 1.4 9.5 1.0 2.4 2 0 0 2 2 2 0 pinin/SDK conserved region Rhabdo_ncap PF00945.18 KEG06499.1 - 4 6.2 4.4 7.5 5.3 4.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cwf_Cwc_15 PF04889.12 KEG06499.1 - 7 6.3 10.2 0.51 10.0 4.4 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_22 PF03901.17 KEG06500.1 - 1.4e-67 228.7 0.1 2.9e-67 227.7 0.1 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family RHSP PF07999.11 KEG06502.1 - 9.4e-91 304.8 0.1 1.5e-90 304.1 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein RAG1_imp_bd PF12560.8 KEG06503.1 - 0.0084 15.7 6.3 0.46 10.0 0.4 2.2 2 0 0 2 2 2 2 RAG1 importin binding DUF4416 PF14385.6 KEG06503.1 - 0.034 14.1 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) DUF2197 PF09963.9 KEG06503.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF2968 PF11180.8 KEG06503.1 - 0.65 9.6 4.1 0.26 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Apolipoprotein PF01442.18 KEG06504.1 - 0.0035 17.2 10.1 0.0064 16.4 10.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain VIR_N PF15912.5 KEG06504.1 - 0.0059 16.2 2.3 0.0059 16.2 2.3 2.1 2 0 0 2 2 2 1 Virilizer, N-terminal SpoIIID PF12116.8 KEG06504.1 - 0.061 13.4 0.6 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D Xpo1 PF08389.12 KEG06504.1 - 0.12 12.4 1.6 0.18 11.9 1.1 1.5 1 1 0 1 1 1 0 Exportin 1-like protein Pex19 PF04614.12 KEG06504.1 - 0.42 10.3 6.7 0.75 9.5 6.7 1.3 1 0 0 1 1 1 0 Pex19 protein family Exonuc_VII_L PF02601.15 KEG06504.1 - 1.6 8.2 8.7 0.26 10.8 4.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit WD40 PF00400.32 KEG06505.1 - 7.2e-21 74.1 0.1 0.00035 21.3 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG06505.1 - 1.9e-09 37.7 0.0 7.9e-05 22.9 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin_8 PF13905.6 KEG06507.1 - 5.3e-16 58.7 0.1 8.2e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KEG06507.1 - 1.8e-05 24.7 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEG06507.1 - 0.018 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin BBIP10 PF14777.6 KEG06508.1 - 1.9e-17 62.6 0.6 2.3e-17 62.3 0.6 1.1 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 Imm70 PF15601.6 KEG06509.1 - 0.014 14.9 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 70 Baculo_PEP_C PF04513.12 KEG06509.1 - 0.07 13.2 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KEG06509.1 - 0.14 12.2 3.3 0.11 12.6 0.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KEG06509.1 - 1.4 7.7 18.5 0.12 11.2 5.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KEG06509.1 - 3.7 7.6 13.4 2.1 8.4 3.3 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 KEG06509.1 - 9.3 5.2 12.2 0.25 10.4 4.5 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mucin PF01456.17 KEG06510.1 - 2.3e-05 24.4 6.5 2.3e-05 24.4 6.5 4.0 1 1 2 3 3 3 2 Mucin-like glycoprotein Alanine_zipper PF11839.8 KEG06510.1 - 0.0055 17.1 14.8 0.0055 17.1 14.8 4.7 3 1 1 4 4 4 3 Alanine-zipper, major outer membrane lipoprotein Alanine_zipper PF11839.8 KEG06511.1 - 0.0042 17.4 8.5 0.0042 17.4 8.5 3.5 2 1 1 3 3 3 1 Alanine-zipper, major outer membrane lipoprotein SepF PF04472.12 KEG06511.1 - 0.079 13.2 0.1 8.1 6.8 0.1 2.8 3 0 0 3 3 3 0 Cell division protein SepF DASH_Dad2 PF08654.10 KEG06511.1 - 0.14 12.6 9.9 0.94 9.9 0.6 2.9 1 1 2 3 3 3 0 DASH complex subunit Dad2 TFR_dimer PF04253.15 KEG06511.1 - 2 8.5 5.6 7 6.8 4.3 2.6 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain Sec23_trunk PF04811.15 KEG06512.1 - 1.7e-45 155.5 0.0 3.9e-45 154.3 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEG06512.1 - 1.5e-21 76.2 0.0 2.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KEG06512.1 - 9.5e-21 74.4 0.1 2.1e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KEG06512.1 - 6.5e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KEG06512.1 - 0.00033 20.7 7.2 0.00078 19.4 7.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Prok-RING_1 PF14446.6 KEG06512.1 - 1.6 8.7 4.9 3.7 7.6 4.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CCHC PF00098.23 KEG06513.1 - 0.015 15.4 3.9 0.027 14.6 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 KEG06513.1 - 0.02 14.8 2.0 0.031 14.3 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KEG06513.1 - 0.027 14.2 0.7 0.057 13.1 0.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KEG06513.1 - 0.052 13.4 1.2 0.087 12.7 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Adaptin_N PF01602.20 KEG06517.1 - 6.4e-72 242.8 6.7 9.2e-72 242.3 6.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KEG06517.1 - 1.2e-51 174.0 0.0 2.8e-51 172.8 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KEG06517.1 - 4.7e-42 143.2 0.0 9.8e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KEG06517.1 - 1.5e-08 34.9 8.3 0.28 11.6 0.1 5.7 4 3 2 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KEG06517.1 - 1.2e-06 28.6 2.4 0.00042 20.4 0.1 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEG06517.1 - 2.2e-05 24.3 4.4 0.37 11.2 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KEG06517.1 - 0.084 13.4 1.1 82 3.9 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat STELLO PF03385.17 KEG06517.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases mRNA_stabil PF13929.6 KEG06517.1 - 0.15 11.0 1.6 0.52 9.2 0.1 2.3 3 0 0 3 3 3 0 mRNA stabilisation Coatomer_g_Cpla PF16381.5 KEG06517.1 - 0.17 12.1 1.9 1.7 8.8 0.4 3.1 2 1 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform RRM_1 PF00076.22 KEG06518.1 - 1.1e-08 34.7 0.0 0.0061 16.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG06518.1 - 0.00086 18.9 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NuDC PF16273.5 KEG06518.1 - 6.5 7.4 5.4 92 3.7 5.4 2.5 1 1 0 1 1 1 0 Nuclear distribution C domain Ras PF00071.22 KEG06521.1 - 9.9e-55 184.6 2.7 4.1e-54 182.6 2.7 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEG06521.1 - 2.9e-36 124.3 0.2 4.6e-36 123.7 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG06521.1 - 5.4e-13 48.8 0.0 6.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG06521.1 - 1.9e-07 31.1 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEG06521.1 - 1.3e-06 28.0 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 KEG06521.1 - 4.2e-05 23.2 0.2 0.094 12.3 0.0 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KEG06521.1 - 4.5e-05 23.1 0.2 0.0014 18.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEG06521.1 - 0.001 19.0 0.1 0.079 12.9 0.1 2.6 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KEG06521.1 - 0.011 15.4 0.2 0.023 14.4 0.1 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KEG06521.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEG06521.1 - 0.025 15.0 0.3 0.041 14.3 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KEG06521.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEG06521.1 - 0.031 13.5 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 KEG06521.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KEG06521.1 - 0.048 13.2 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KEG06521.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KEG06521.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KEG06521.1 - 0.1 13.0 0.1 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KEG06521.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Herpes_US9 PF06072.11 KEG06522.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 NPBW PF15180.6 KEG06523.1 - 0.032 14.1 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Neuropeptides B and W YdfZ PF14001.6 KEG06523.1 - 0.14 12.6 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 YdfZ protein Spt20 PF12090.8 KEG06523.1 - 0.8 9.3 9.5 1.2 8.6 3.7 2.3 2 0 0 2 2 2 0 Spt20 family Aa_trans PF01490.18 KEG06524.1 - 1.5e-50 172.1 35.0 1.8e-50 171.9 35.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG06524.1 - 1e-09 37.9 11.7 1e-09 37.9 11.7 2.7 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family Baculo_E56 PF04639.12 KEG06524.1 - 0.065 12.5 0.1 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope Galactosyl_T PF01762.21 KEG06525.1 - 0.00058 19.7 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Galactosyltransferase Sid-5 PF17204.3 KEG06525.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Sid-5 family IHO1 PF15771.5 KEG06528.1 - 0.0076 15.1 12.0 0.0087 14.9 12.0 1.0 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 Cupin_5 PF06172.11 KEG06529.1 - 1.4e-44 151.7 0.0 1.6e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Mod_r PF07200.13 KEG06530.1 - 1.7e-13 50.9 3.7 2.8e-13 50.2 3.7 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Cnn_1N PF07989.11 KEG06530.1 - 0.00037 20.6 0.4 0.0012 18.9 0.4 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 FliD_C PF07195.12 KEG06530.1 - 0.0018 17.8 0.5 0.0064 15.9 0.1 1.9 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus COG7 PF10191.9 KEG06530.1 - 0.002 16.5 0.2 0.0026 16.1 0.2 1.2 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DMPK_coil PF08826.10 KEG06530.1 - 0.0048 17.0 1.6 0.077 13.1 0.6 2.7 2 0 0 2 2 2 1 DMPK coiled coil domain like CP12 PF02672.15 KEG06530.1 - 0.016 15.9 0.3 0.035 14.8 0.3 1.6 1 0 0 1 1 1 0 CP12 domain DUF1640 PF07798.11 KEG06530.1 - 0.03 14.4 0.8 0.038 14.0 0.2 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1640) FlaG PF03646.15 KEG06530.1 - 0.042 14.0 0.5 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 FlaG protein DUF4763 PF15960.5 KEG06530.1 - 0.085 12.2 4.9 0.066 12.5 3.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) GIT_CC PF16559.5 KEG06530.1 - 0.089 12.7 7.2 0.098 12.5 1.2 2.8 2 1 1 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HalX PF08663.10 KEG06530.1 - 0.092 13.1 0.9 0.092 13.1 0.9 3.1 2 1 1 3 3 3 0 HalX domain Lzipper-MIP1 PF14389.6 KEG06530.1 - 0.12 12.7 4.3 0.13 12.6 0.5 2.8 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 KEG06530.1 - 0.14 12.7 4.8 0.091 13.3 2.0 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 KEG06530.1 - 0.16 11.8 4.6 0.19 11.5 1.9 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.15 KEG06530.1 - 0.18 11.6 2.5 0.35 10.7 1.3 2.1 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.11 KEG06530.1 - 0.18 12.0 5.3 0.091 13.0 1.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 KEG06530.1 - 0.19 12.2 5.8 0.16 12.5 3.6 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Prefoldin_2 PF01920.20 KEG06530.1 - 0.23 11.4 5.8 0.47 10.4 3.7 2.5 3 0 0 3 3 3 0 Prefoldin subunit ADIP PF11559.8 KEG06530.1 - 0.28 11.3 4.4 0.25 11.4 1.9 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 KEG06530.1 - 0.33 10.3 8.4 0.22 10.9 3.1 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 KEG06530.1 - 0.47 10.8 6.9 0.1 13.0 2.0 2.4 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 KEG06530.1 - 0.52 10.6 6.7 1.2 9.4 3.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 KEG06530.1 - 0.62 10.6 10.0 0.44 11.0 1.6 3.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Rho_Binding PF08912.11 KEG06530.1 - 0.9 10.4 4.4 0.53 11.1 1.4 2.2 2 1 1 3 3 2 0 Rho Binding Seryl_tRNA_N PF02403.22 KEG06530.1 - 1.2 9.5 6.4 0.3 11.3 2.7 2.0 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 KEG06530.1 - 3.2 8.4 8.3 0.74 10.5 2.2 2.8 3 0 0 3 3 3 0 SlyX Csm1_N PF18504.1 KEG06530.1 - 3.5 8.0 9.7 0.085 13.2 2.2 2.2 4 0 0 4 4 1 0 Csm1 N-terminal domain Pox_A_type_inc PF04508.12 KEG06530.1 - 4.1 7.4 7.5 7.3 6.6 0.1 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat F_actin_cap_B PF01115.17 KEG06531.1 - 0.18 11.4 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 F-actin capping protein, beta subunit TMEM132D_C PF15706.5 KEG06532.1 - 0.16 11.8 0.8 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mucin PF01456.17 KEG06534.1 - 0.57 10.2 31.6 3 7.8 2.6 2.7 2 1 0 2 2 2 0 Mucin-like glycoprotein SUIM_assoc PF16619.5 KEG06536.1 - 0.28 11.3 0.0 0.28 11.3 0.0 7.1 5 2 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Cpn10 PF00166.21 KEG06538.1 - 2.8e-21 75.3 0.0 3.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Acyl-ACP_TE PF01643.17 KEG06539.1 - 1.2e-06 28.0 0.0 4.3e-05 22.9 0.1 2.5 2 1 0 2 2 2 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KEG06539.1 - 0.063 13.8 0.1 0.23 12.0 0.1 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily Vicilin_N PF04702.12 KEG06541.1 - 6.9e-06 26.0 1.0 1e-05 25.4 1.0 1.2 1 0 0 1 1 1 1 Vicilin N terminal region DUF3339 PF11820.8 KEG06541.1 - 0.0047 17.1 0.2 0.0099 16.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3339) DUF5585 PF17823.1 KEG06541.1 - 0.058 12.3 0.4 0.094 11.7 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Sec23_trunk PF04811.15 KEG06546.1 - 0.029 13.9 0.2 0.071 12.7 0.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain BORCS8 PF10167.9 KEG06546.1 - 0.15 12.0 3.0 0.34 10.9 0.6 2.7 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF1664 PF07889.12 KEG06546.1 - 0.42 10.7 9.8 1 9.4 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KEG06546.1 - 9.5 6.3 22.9 0.22 11.6 5.0 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF241 PF03087.14 KEG06547.1 - 0.42 10.4 28.4 1.7 8.5 11.4 2.2 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Vps39_2 PF10367.9 KEG06547.1 - 2.5 8.6 6.4 8.8 6.8 1.4 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Caprin-1_dimer PF18293.1 KEG06547.1 - 5.8 7.4 14.6 2.7 8.5 1.4 3.7 2 2 1 4 4 4 0 Caprin-1 dimerization domain Thioredoxin PF00085.20 KEG06549.1 - 3.7e-26 91.1 0.0 2.9e-24 85.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KEG06549.1 - 5.4e-11 42.9 0.0 3.4e-06 27.4 0.1 3.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEG06549.1 - 2.4e-06 27.8 0.0 0.0097 16.2 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 KEG06549.1 - 0.0019 17.6 0.0 0.033 13.5 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KEG06549.1 - 0.0029 17.3 0.0 0.0077 15.9 0.0 1.7 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 KEG06549.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 KEG06549.1 - 0.007 16.3 0.0 3.6 7.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KEG06549.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 KEG06549.1 - 0.013 15.3 0.0 0.68 9.7 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KEG06549.1 - 0.019 15.1 0.0 0.091 13.0 0.0 2.1 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin_5 PF13743.6 KEG06549.1 - 0.05 13.3 0.0 7.4 6.2 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin Ribos_L4_asso_C PF14374.6 KEG06549.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain NUDIX PF00293.28 KEG06550.1 - 3.3e-05 23.9 0.0 8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_N PF02771.16 KEG06550.1 - 0.12 13.1 1.6 4.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain ABA_GPCR PF12430.8 KEG06551.1 - 1.4e-11 44.5 4.4 1.4e-11 44.5 4.4 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KEG06551.1 - 4.2e-08 33.1 0.1 8.4e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Gln-synt_C PF00120.24 KEG06552.1 - 4.9e-17 61.9 0.0 4.5e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KEG06552.1 - 1.6e-11 43.8 0.0 2.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain LRR_6 PF13516.6 KEG06553.1 - 0.027 14.5 0.1 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeat LRR_8 PF13855.6 KEG06553.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat Alanine_zipper PF11839.8 KEG06555.1 - 0.0057 17.0 8.6 0.0057 17.0 8.6 7.1 4 2 3 7 7 7 3 Alanine-zipper, major outer membrane lipoprotein DUF2937 PF11157.8 KEG06555.1 - 2 8.1 5.2 5.4 6.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) CAP_N PF01213.19 KEG06556.1 - 0.033 13.7 4.6 0.051 13.1 4.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PepSY_TM PF03929.16 KEG06556.1 - 0.036 13.7 2.3 0.072 12.8 2.3 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Pex14_N PF04695.13 KEG06556.1 - 0.64 10.7 12.0 1.4 9.6 12.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 KEG06556.1 - 2.5 7.0 4.3 3.4 6.5 4.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1180 PF06679.12 KEG06556.1 - 2.6 8.5 8.8 5.5 7.4 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SARAF PF06682.12 KEG06556.1 - 5.1 6.7 7.8 7.9 6.0 7.8 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 KEG06556.1 - 6.7 7.1 12.7 12 6.3 12.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5327 PF17261.2 KEG06556.1 - 8.4 7.2 9.7 17 6.3 9.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) SLC3A2_N PF16028.5 KEG06557.1 - 0.043 13.4 1.9 0.063 12.8 1.9 1.2 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Amastin PF07344.11 KEG06559.1 - 2.5e-07 30.7 5.5 2.5e-07 30.7 5.5 1.5 1 1 1 2 2 2 1 Amastin surface glycoprotein Peptidase_U4 PF03419.13 KEG06559.1 - 1.1 8.4 5.0 1.8 7.8 5.0 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RNA_pol_Rpb6 PF01192.22 KEG06560.1 - 4.6e-16 58.5 0.1 7.1e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Amastin PF07344.11 KEG06562.1 - 7.7e-07 29.1 6.6 7.7e-07 29.1 6.6 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein EMP70 PF02990.16 KEG06562.1 - 0.64 8.6 7.7 0.79 8.3 7.7 1.3 1 1 0 1 1 1 0 Endomembrane protein 70 APP_Cu_bd PF12924.7 KEG06563.1 - 0.15 12.9 0.0 0.26 12.1 0.0 1.4 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Metallophos PF00149.28 KEG06564.1 - 6.1e-36 124.8 0.0 7.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEG06564.1 - 2.7e-09 37.3 0.1 7.8e-07 29.4 0.1 2.5 2 0 0 2 2 2 2 Serine-threonine protein phosphatase N-terminal domain Pyr_redox_dim PF02852.22 KEG06565.1 - 1.2e-16 61.0 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain zf_UBZ PF18439.1 KEG06566.1 - 0.0002 20.9 0.3 1.9 8.1 0.0 3.7 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 KEG06566.1 - 0.0027 18.2 0.9 12 6.8 0.0 4.1 4 0 0 4 4 4 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_4 PF13894.6 KEG06566.1 - 0.017 15.9 1.7 25 6.1 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CRD PF17979.1 KEG06566.1 - 0.055 13.6 4.2 0.11 12.6 4.2 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-TRAF PF02176.18 KEG06566.1 - 0.092 13.4 11.1 0.058 14.1 2.4 3.0 2 1 1 3 3 3 0 TRAF-type zinc finger zf-Di19 PF05605.12 KEG06566.1 - 0.25 11.7 9.1 1.9 8.9 2.1 3.4 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 KEG06566.1 - 0.42 10.1 7.2 10 5.7 0.7 3.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-TFIIB PF13453.6 KEG06566.1 - 0.9 8.9 7.0 1.2 8.6 0.2 3.4 4 0 0 4 4 4 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.6 KEG06566.1 - 1.4 8.7 8.7 15 5.5 0.1 4.4 4 1 0 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.26 KEG06566.1 - 4.6 7.9 7.8 13 6.4 0.1 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Mucin PF01456.17 KEG06567.1 - 1.7e-05 24.8 12.0 1.7e-05 24.8 12.0 4.6 1 1 2 4 4 4 1 Mucin-like glycoprotein DUF3192 PF11399.8 KEG06567.1 - 0.089 12.7 1.7 29 4.7 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3192) Mucin PF01456.17 KEG06568.1 - 2.5e-07 30.8 44.4 4.5e-07 30.0 3.9 3.4 2 1 0 2 2 2 1 Mucin-like glycoprotein MCM_bind PF09739.9 KEG06568.1 - 0.2 10.1 2.6 0.081 11.4 0.5 1.3 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Mucin PF01456.17 KEG06569.1 - 9.4e-05 22.4 27.0 0.00081 19.4 27.0 2.0 1 1 0 1 1 1 1 Mucin-like glycoprotein Seryl_tRNA_N PF02403.22 KEG06569.1 - 0.67 10.2 5.5 0.39 11.0 3.3 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Peptidase_M8 PF01457.16 KEG06574.1 - 1.3e-144 482.8 0.2 1.7e-144 482.4 0.2 1.0 1 0 0 1 1 1 1 Leishmanolysin EspB_PE PF18625.1 KEG06575.1 - 6.1 7.4 8.8 1.4 9.5 1.2 3.9 4 0 0 4 4 4 0 ESX-1 secreted protein B PE domain LRR_9 PF14580.6 KEG06578.1 - 1.1e-13 51.1 0.5 2e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KEG06578.1 - 1.4e-10 40.8 9.2 4.1e-05 23.3 0.2 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KEG06578.1 - 1.9e-10 40.8 2.2 2.5e-05 24.5 1.0 3.6 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) BBIP10 PF14777.6 KEG06578.1 - 3.5 7.3 6.9 0.22 11.1 1.3 1.9 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 SSB PF00436.25 KEG06579.1 - 3.9e-06 26.9 0.0 5.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 KEG06579.1 - 0.016 15.2 0.1 0.049 13.6 0.0 1.9 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain RVT_1 PF00078.27 KEG06582.1 - 3.2e-06 26.8 0.0 3.6e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RXLR PF16810.5 KEG06586.1 - 5.1 7.5 7.9 1.2 9.6 1.5 2.6 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Snf7 PF03357.21 KEG06588.1 - 3.1e-33 114.8 28.1 3.1e-33 114.8 28.1 1.8 1 1 1 2 2 2 1 Snf7 DUF4580 PF15162.6 KEG06588.1 - 0.013 15.0 1.5 0.02 14.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) DUF2072 PF09845.9 KEG06588.1 - 1.7 8.9 9.8 0.4 10.9 0.4 2.4 2 1 0 2 2 2 0 Zn-ribbon containing protein PhyH PF05721.13 KEG06591.1 - 5e-36 125.0 0.0 7e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF563 PF04577.14 KEG06592.1 - 2e-14 54.3 0.0 3.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ferric_reduct PF01794.19 KEG06593.1 - 8.4e-15 55.0 7.6 8.4e-15 55.0 7.6 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEG06593.1 - 2.3e-11 44.1 0.0 1.4e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEG06593.1 - 8.6e-10 38.7 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KEG06593.1 - 0.00093 19.8 0.0 0.44 11.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain ACR_tran PF00873.19 KEG06596.1 - 0.24 9.0 5.7 0.47 8.0 5.7 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Caskin-tail PF16632.5 KEG06596.1 - 0.57 10.6 0.1 0.57 10.6 0.1 5.7 3 1 1 6 6 6 0 C-terminal region of Caskin Alanine_zipper PF11839.8 KEG06596.1 - 3.8 7.9 79.4 0.038 14.4 12.9 5.3 4 2 1 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein MIP PF00230.20 KEG06599.1 - 2.4e-31 109.2 11.0 3.4e-31 108.7 11.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF4257 PF14074.6 KEG06599.1 - 0.0031 17.7 0.3 0.006 16.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) Oxidored_q3 PF00499.20 KEG06599.1 - 0.027 14.2 2.8 0.23 11.2 0.3 2.9 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 OATP PF03137.20 KEG06599.1 - 0.28 9.4 4.7 0.17 10.1 0.2 2.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPR_7 PF13176.6 KEG06600.1 - 0.04 13.9 0.9 12 6.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG06600.1 - 0.078 13.3 2.0 5 7.5 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Rac1 PF09632.10 KEG06600.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Rac1-binding domain GREB1 PF15782.5 KEG06602.1 - 4.8 4.2 9.8 7.5 3.5 9.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Retinal PF15449.6 KEG06603.1 - 7.7 4.2 22.9 10 3.8 22.9 1.0 1 0 0 1 1 1 0 Retinal protein WAK_assoc PF14380.6 KEG06604.1 - 0.11 13.3 4.5 0.19 12.5 4.5 1.5 1 1 0 1 1 1 0 Wall-associated receptor kinase C-terminal YAF2_RYBP PF17219.3 KEG06605.1 - 0.077 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif Mucin PF01456.17 KEG06606.1 - 0.0056 16.7 20.4 0.0056 16.7 20.4 5.5 1 1 2 3 3 3 1 Mucin-like glycoprotein Tropomyosin PF00261.20 KEG06607.1 - 0.0074 15.7 3.7 0.0074 15.7 3.7 2.9 2 1 0 2 2 2 1 Tropomyosin SNARE PF05739.19 KEG06607.1 - 0.041 13.9 2.4 0.11 12.5 0.7 2.6 1 1 1 2 2 2 0 SNARE domain Utp13 PF08625.11 KEG06607.1 - 0.18 11.7 2.7 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Ribosomal_S30AE PF02482.19 KEG06607.1 - 1.3 9.9 6.8 0.46 11.3 2.4 2.5 1 1 1 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein CD34_antigen PF06365.12 KEG06609.1 - 0.0025 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family VSP PF03302.13 KEG06609.1 - 0.0077 15.1 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF2371 PF10177.9 KEG06609.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) PTP_tm PF18861.1 KEG06609.1 - 0.8 9.7 2.4 1.5 8.8 2.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Pro_isomerase PF00160.21 KEG06610.1 - 9.3e-39 133.2 0.0 4.4e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4920 PF16267.5 KEG06610.1 - 0.061 13.3 1.3 0.19 11.7 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4920) DUF4926 PF16277.5 KEG06610.1 - 0.075 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) TetR_C_28 PF17937.1 KEG06610.1 - 0.076 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CIDE-N PF02017.15 KEG06610.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 CIDE-N domain zf_CCCH_4 PF18345.1 KEG06611.1 - 1.2e-08 34.7 42.5 3.1e-06 27.0 5.0 5.3 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 KEG06611.1 - 0.0005 19.8 2.8 0.0005 19.8 2.8 4.9 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KEG06611.1 - 0.0011 19.2 0.3 0.0011 19.2 0.3 3.7 3 2 1 4 4 4 1 Zinc-finger containing family SUIM_assoc PF16619.5 KEG06611.1 - 0.0015 18.5 3.4 0.0054 16.8 3.4 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 zf-CCCH PF00642.24 KEG06611.1 - 0.005 16.7 37.1 0.081 12.9 1.6 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG06611.1 - 0.015 16.0 5.2 0.015 16.0 5.2 4.9 2 2 3 5 5 5 0 Torus domain ANAPC_CDC26 PF10471.9 KEG06611.1 - 0.72 10.7 8.1 0.71 10.7 4.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RRM_1 PF00076.22 KEG06613.1 - 9.5e-22 76.6 0.0 6.4e-15 54.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KEG06613.1 - 0.11 12.2 0.1 0.37 10.6 0.1 1.8 1 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain zf-CCCH PF00642.24 KEG06614.1 - 1.4e-06 28.1 4.1 2.2e-06 27.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG06614.1 - 2.4e-05 24.0 4.7 2.4e-05 24.0 4.7 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG06614.1 - 0.0027 17.7 1.2 0.0027 17.7 1.2 2.3 2 1 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KEG06614.1 - 0.016 15.9 0.2 0.019 15.7 0.2 1.1 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KEG06614.1 - 0.038 14.5 1.7 0.038 14.5 1.7 1.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nas2_N PF18265.1 KEG06615.1 - 1e-24 86.2 0.4 1.5e-24 85.7 0.0 1.4 2 0 0 2 2 2 1 Nas2 N_terminal domain Borrelia_REV PF03978.13 KEG06615.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Pkinase PF00069.25 KEG06616.1 - 1.3e-64 218.2 0.0 1.9e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06616.1 - 1.3e-45 155.8 0.0 1.9e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG06616.1 - 6.3e-05 21.9 0.0 9.7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1856 PF08983.10 KEG06616.1 - 0.022 15.0 0.3 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) Kinase-like PF14531.6 KEG06616.1 - 0.16 11.2 0.1 0.59 9.4 0.1 2.0 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KEG06616.1 - 0.17 11.7 0.7 17 5.2 0.0 3.4 3 1 1 4 4 4 0 Phosphotransferase enzyme family Met_10 PF02475.16 KEG06617.1 - 7.1e-47 159.7 0.2 2.3e-34 118.9 0.0 2.2 1 1 1 2 2 2 2 Met-10+ like-protein PrmA PF06325.13 KEG06617.1 - 0.0023 17.4 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 KEG06617.1 - 0.0067 15.6 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase AFT PF08731.11 KEG06617.1 - 0.036 14.5 0.2 0.059 13.8 0.2 1.3 1 0 0 1 1 1 0 Transcription factor AFT MTS PF05175.14 KEG06617.1 - 0.049 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-C2H2_4 PF13894.6 KEG06618.1 - 2.2e-07 31.2 23.4 0.13 13.2 0.5 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.12 KEG06618.1 - 7.3e-07 29.4 12.6 0.01 16.1 0.1 4.2 4 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KEG06618.1 - 0.00031 20.3 7.3 2.6 7.8 0.0 4.2 4 0 0 4 4 4 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KEG06618.1 - 0.024 14.9 6.5 4.2 7.8 0.2 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KEG06618.1 - 0.025 14.2 0.0 22 4.8 0.0 3.3 3 0 0 3 3 3 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KEG06618.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain CpXC PF14353.6 KEG06618.1 - 0.29 11.2 1.4 5.6 7.0 0.4 2.5 2 0 0 2 2 2 0 CpXC protein zf-met PF12874.7 KEG06618.1 - 2 8.9 6.8 11 6.6 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KEG06618.1 - 3.2 7.6 5.9 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KEG06618.1 - 5.6 7.6 22.4 19 5.9 0.2 6.5 6 1 0 6 6 6 0 Zinc-finger double domain zf-BED PF02892.15 KEG06618.1 - 8.8 6.4 10.4 2.5 8.2 0.5 3.9 4 0 0 4 4 4 0 BED zinc finger RNase_H PF00075.24 KEG06619.1 - 4.4e-07 30.2 0.0 7.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNase H SMN PF06003.12 KEG06619.1 - 0.76 9.0 3.4 1.2 8.3 3.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ectatomin PF06457.11 KEG06624.1 - 0.099 12.6 0.3 0.26 11.2 0.3 1.7 1 0 0 1 1 1 0 Ectatomin DUF4580 PF15162.6 KEG06625.1 - 0.09 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) RNA_pol_N PF01194.17 KEG06626.1 - 4e-25 87.9 0.3 4.6e-25 87.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KEG06626.1 - 0.097 12.9 0.8 0.19 12.0 0.8 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF155 PF02582.14 KEG06627.1 - 6.4e-40 137.1 0.0 9.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mid2 PF04478.12 KEG06629.1 - 4.8e-09 36.2 1.0 7.9e-09 35.5 1.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KEG06629.1 - 0.0006 19.2 1.8 0.0006 19.2 1.8 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MLANA PF14991.6 KEG06629.1 - 0.089 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A TMIE PF16038.5 KEG06629.1 - 3.4 7.6 4.6 6.8 6.6 4.6 1.5 1 0 0 1 1 1 0 TMIE protein zf-C2H2_4 PF13894.6 KEG06631.1 - 4.3e-08 33.3 8.6 0.21 12.5 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KEG06631.1 - 3e-06 27.4 2.3 0.0032 17.7 0.1 3.2 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KEG06631.1 - 0.00014 21.5 0.8 1.1 9.0 0.4 3.2 3 0 0 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 KEG06631.1 - 0.017 14.9 3.9 0.13 12.1 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KEG06631.1 - 0.022 15.2 11.5 3.4 8.3 0.0 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-BED PF02892.15 KEG06631.1 - 0.024 14.7 4.9 0.73 9.9 0.2 3.3 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.8 KEG06631.1 - 0.029 14.7 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KEG06631.1 - 0.038 14.7 0.2 13 6.5 0.0 2.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KEG06631.1 - 0.045 14.2 16.5 7.9 7.1 4.3 5.0 4 1 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.7 KEG06631.1 - 0.11 13.0 0.1 7.5 7.1 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KEG06631.1 - 0.27 11.1 1.0 4.1 7.3 0.0 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF3552 PF12072.8 KEG06634.1 - 6.8e-05 22.4 8.8 9.5e-05 21.9 8.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Allexi_40kDa PF05549.11 KEG06634.1 - 0.0096 15.5 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF16 PF01519.16 KEG06634.1 - 0.034 14.6 0.9 0.073 13.6 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 KEG06634.1 - 0.1 12.2 3.3 0.12 12.0 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MCU PF04678.13 KEG06634.1 - 0.22 11.6 2.8 0.3 11.1 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spc7 PF08317.11 KEG06634.1 - 0.31 9.9 7.3 0.42 9.4 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 KEG06634.1 - 0.45 10.9 7.9 0.7 10.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 KEG06634.1 - 0.7 7.3 11.0 0.78 7.2 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 KEG06634.1 - 0.88 9.8 9.8 7.2 6.9 9.5 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CorA PF01544.18 KEG06634.1 - 1.1 8.5 2.6 1.3 8.3 2.6 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_Mu_F PF04233.14 KEG06634.1 - 1.6 9.5 9.3 0.42 11.4 3.0 2.0 1 1 1 2 2 2 0 Phage Mu protein F like protein Plus-3 PF03126.18 KEG06636.1 - 2.5e-19 69.8 0.6 3.6e-19 69.3 0.1 1.5 2 0 0 2 2 2 1 Plus-3 domain zf-C3HC4_3 PF13920.6 KEG06636.1 - 4e-07 29.8 20.9 6.3e-07 29.1 20.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 KEG06636.1 - 0.047 14.1 5.2 0.088 13.3 4.8 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 P66_CC PF16563.5 KEG06636.1 - 0.21 11.2 3.1 0.46 10.1 3.1 1.6 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 FYVE_2 PF02318.16 KEG06636.1 - 5 7.4 15.7 15 5.8 15.7 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger Galactosyl_T PF01762.21 KEG06639.1 - 0.00051 19.9 0.0 0.94 9.3 0.0 3.6 2 1 1 3 3 3 2 Galactosyltransferase CPT_N PF16484.5 KEG06639.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Galactosyl_T PF01762.21 KEG06640.1 - 2.4e-05 24.2 0.0 0.66 9.8 0.0 3.6 3 1 1 4 4 4 3 Galactosyltransferase PEX11 PF05648.14 KEG06640.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) V-SNARE_C PF12352.8 KEG06641.1 - 2.3e-09 37.4 4.5 3.2e-09 36.9 4.5 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KEG06641.1 - 1.8e-08 34.2 3.3 2.4e-08 33.8 3.3 1.2 1 0 0 1 1 1 1 Sec20 OAD_gamma PF04277.13 KEG06641.1 - 0.0009 19.8 0.1 0.0028 18.2 0.0 1.8 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain Baculo_F PF12259.8 KEG06641.1 - 0.0069 15.0 0.4 0.0081 14.7 0.4 1.1 1 0 0 1 1 1 1 Baculovirus F protein Ferlin_C PF16165.5 KEG06641.1 - 0.011 15.7 0.5 0.014 15.3 0.5 1.2 1 0 0 1 1 1 0 Ferlin C-terminus MSC PF09402.10 KEG06641.1 - 0.012 15.1 2.3 0.013 14.9 2.3 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain YukC PF10140.9 KEG06641.1 - 0.021 13.7 1.0 0.023 13.5 1.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF2116 PF09889.9 KEG06641.1 - 0.023 14.7 0.7 0.039 13.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Amnionless PF14828.6 KEG06641.1 - 0.029 13.2 0.5 0.031 13.1 0.5 1.0 1 0 0 1 1 1 0 Amnionless DUF3402 PF11882.8 KEG06641.1 - 0.03 13.4 0.2 0.032 13.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) TMEM154 PF15102.6 KEG06641.1 - 0.031 14.2 3.4 0.044 13.7 3.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family TMP_2 PF06791.13 KEG06641.1 - 0.031 13.9 2.2 0.039 13.6 2.2 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Virul_fac_BrkB PF03631.15 KEG06641.1 - 0.036 13.7 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Virulence factor BrkB OppC_N PF12911.7 KEG06641.1 - 0.038 14.0 0.1 0.053 13.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Glycophorin_A PF01102.18 KEG06641.1 - 0.049 13.9 1.8 0.071 13.4 1.5 1.3 1 1 0 1 1 1 0 Glycophorin A KxDL PF10241.9 KEG06641.1 - 0.051 13.9 0.8 0.051 13.9 0.8 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF2142 PF09913.9 KEG06641.1 - 0.067 12.0 0.3 0.082 11.8 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) LAP1C PF05609.12 KEG06641.1 - 0.073 12.2 2.8 0.084 11.9 2.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF5089 PF17002.5 KEG06641.1 - 0.074 12.9 6.6 0.1 12.5 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) DUF3464 PF11947.8 KEG06641.1 - 0.082 12.7 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Insulin_TMD PF17870.1 KEG06641.1 - 0.088 12.9 1.3 0.13 12.4 1.3 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Vma12 PF11712.8 KEG06641.1 - 0.091 12.8 1.5 0.11 12.6 1.5 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3979 PF13141.6 KEG06641.1 - 0.15 12.3 0.6 0.19 12.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Spc7 PF08317.11 KEG06641.1 - 0.15 10.9 5.3 0.17 10.7 5.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Orf78 PF06024.12 KEG06641.1 - 0.35 11.2 3.7 0.59 10.5 3.7 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Synaptobrevin PF00957.21 KEG06641.1 - 0.35 10.7 11.1 0.24 11.2 7.7 2.2 1 1 1 2 2 2 0 Synaptobrevin Fusion_gly PF00523.18 KEG06641.1 - 0.41 8.8 8.1 0.77 7.9 3.2 2.0 1 1 1 2 2 2 0 Fusion glycoprotein F0 HSCB_C PF07743.13 KEG06641.1 - 1 9.9 3.7 2.4 8.7 3.7 1.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain DASH_Duo1 PF08651.10 KEG06641.1 - 3.1 7.6 8.2 0.56 10.0 2.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 RTT107_BRCT_5 PF16770.5 KEG06642.1 - 0.00039 20.2 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KEG06642.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KEG06642.1 - 0.00089 19.6 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Argos PF11581.8 KEG06644.1 - 0.063 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos TPR_2 PF07719.17 KEG06647.1 - 5.8e-07 29.1 14.6 0.0077 16.3 0.2 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEG06647.1 - 8.2e-05 23.0 3.4 2.9 8.7 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG06647.1 - 0.00011 22.8 11.9 0.0095 16.7 1.2 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG06647.1 - 0.00021 21.7 7.1 0.011 16.3 1.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG06647.1 - 0.0016 19.1 6.9 0.0074 16.9 3.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG06647.1 - 0.048 13.9 9.8 0.81 10.0 3.3 3.0 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KEG06647.1 - 0.05 13.9 18.9 7.4 6.9 5.2 4.4 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG06647.1 - 0.11 12.9 8.5 1.3 9.5 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat His_binding PF02098.16 KEG06647.1 - 0.12 12.4 0.5 0.2 11.7 0.5 1.3 1 0 0 1 1 1 0 Tick histamine binding protein TPR_1 PF00515.28 KEG06647.1 - 0.16 11.9 15.6 0.21 11.4 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG06647.1 - 0.95 9.6 7.2 1.2 9.3 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 KEG06648.1 - 3.4e-11 43.2 0.2 6e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEG06648.1 - 1.6e-06 28.0 0.0 4.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 KEG06648.1 - 4.5e-06 25.9 0.1 3.3e-05 23.1 0.1 2.2 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KEG06648.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 Ras PF00071.22 KEG06650.1 - 0.089 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Ras family Pkinase PF00069.25 KEG06651.1 - 1.6e-53 181.8 0.0 2e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06651.1 - 1.8e-35 122.5 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06651.1 - 0.00059 19.2 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG06651.1 - 0.074 11.8 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase VEFS-Box PF09733.9 KEG06652.1 - 0.032 14.0 0.2 0.18 11.6 0.0 1.9 1 1 1 2 2 2 0 VEFS-Box of polycomb protein EMP70 PF02990.16 KEG06653.1 - 1.1e-123 413.7 7.7 1.1e-123 413.7 7.7 1.3 1 1 0 1 1 1 1 Endomembrane protein 70 DUF4288 PF14119.6 KEG06655.1 - 0.38 11.2 2.2 1.1 9.7 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Paramyxo_NS_C PF02725.14 KEG06656.1 - 0.06 13.5 0.4 0.17 12.0 0.4 1.8 1 0 0 1 1 1 0 Non-structural protein C APG6 PF04111.12 KEG06660.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Apg6 BARA domain Rootletin PF15035.6 KEG06661.1 - 0.0082 16.2 9.7 0.014 15.5 9.7 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion MCC-bdg_PDZ PF10506.9 KEG06661.1 - 0.013 15.5 4.7 0.42 10.7 1.7 2.6 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HOOK PF05622.12 KEG06661.1 - 0.049 11.8 11.5 0.078 11.1 11.5 1.3 1 0 0 1 1 1 0 HOOK protein Atg14 PF10186.9 KEG06661.1 - 0.076 12.1 2.4 0.15 11.2 2.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SSXT PF05030.12 KEG06661.1 - 0.21 11.2 1.1 0.95 9.1 0.5 2.1 2 0 0 2 2 2 0 SSXT protein (N-terminal region) Spc110_C PF18520.1 KEG06661.1 - 0.23 11.1 1.2 0.56 9.8 1.2 1.6 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain Cep57_MT_bd PF06657.13 KEG06661.1 - 0.31 11.5 3.6 7.2 7.1 0.0 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DinB PF05163.12 KEG06661.1 - 0.41 10.6 4.0 0.24 11.3 0.5 2.1 1 1 1 2 2 2 0 DinB family DUF1730 PF08331.10 KEG06661.1 - 0.42 10.5 2.9 1.6 8.7 2.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1730) DUF4254 PF14063.6 KEG06661.1 - 1 9.2 7.6 0.77 9.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) GAS PF13851.6 KEG06661.1 - 6.3 6.1 12.3 20 4.5 10.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DHO_dh PF01180.21 KEG06662.1 - 7.8e-38 130.3 0.0 8.7e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase F_bP_aldolase PF01116.20 KEG06662.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Mucin PF01456.17 KEG06663.1 - 0.0021 18.1 5.5 0.0021 18.1 5.5 3.8 2 1 0 2 2 2 1 Mucin-like glycoprotein Syntaxin-6_N PF09177.11 KEG06663.1 - 0.59 10.7 13.4 1.5 9.5 2.1 3.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TAN PF11640.8 KEG06663.1 - 4 7.6 8.2 0.29 11.2 0.2 2.5 2 1 1 3 3 3 0 Telomere-length maintenance and DNA damage repair Mod_r PF07200.13 KEG06663.1 - 8.2 6.5 14.3 0.85 9.7 4.8 2.7 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Phospholip_B PF04916.13 KEG06665.1 - 4.2e-95 319.3 1.2 4.8e-95 319.1 1.2 1.0 1 0 0 1 1 1 1 Phospholipase B CcmD PF04995.14 KEG06666.1 - 9 6.5 12.2 4.8 7.3 2.5 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) TPR_10 PF13374.6 KEG06668.1 - 0.14 12.1 0.8 0.14 12.1 0.8 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.23 KEG06669.1 - 1.3e-90 303.7 0.1 2e-90 303.1 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG06669.1 - 4.2e-18 65.7 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding RRP36 PF06102.12 KEG06669.1 - 0.079 12.9 0.9 0.17 11.8 0.9 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Peptidase_M18 PF02127.15 KEG06670.1 - 5.9e-158 526.2 0.0 6.7e-158 526.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KEG06670.1 - 3e-10 39.6 0.0 8.1e-08 31.6 0.0 2.1 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase HTH_26 PF13443.6 KEG06670.1 - 0.034 14.6 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain ATP12 PF07542.11 KEG06670.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein MIF PF01187.18 KEG06670.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) DUF423 PF04241.15 KEG06671.1 - 1.1e-23 83.2 1.2 1.5e-23 82.8 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Peptidase_M8 PF01457.16 KEG06672.1 - 8.4e-148 493.3 0.0 1.2e-147 492.8 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.6 KEG06672.1 - 0.095 12.8 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 KEG06672.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Androgen_recep PF02166.16 KEG06673.1 - 0.076 11.8 3.7 0.1 11.4 3.7 1.3 1 0 0 1 1 1 0 Androgen receptor FAM199X PF15814.5 KEG06673.1 - 0.092 11.8 2.1 0.12 11.4 2.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X Macoilin PF09726.9 KEG06673.1 - 0.13 10.8 2.7 0.15 10.6 2.7 1.1 1 0 0 1 1 1 0 Macoilin family CENP-R PF06729.12 KEG06673.1 - 0.4 10.6 2.4 1.8 8.5 3.2 1.6 2 0 0 2 2 2 0 Kinetochore component, CENP-R SelP_N PF04592.14 KEG06673.1 - 0.48 9.8 14.2 0.64 9.4 14.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 KEG06673.1 - 0.93 8.6 2.8 1.1 8.4 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spem1 PF15670.5 KEG06673.1 - 2.8 7.4 10.7 3.8 7.0 10.7 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF563 PF04577.14 KEG06674.1 - 4.2e-07 30.3 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_M8 PF01457.16 KEG06676.1 - 1.9e-107 360.2 5.5 5.4e-54 183.8 2.5 2.0 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG06676.1 - 0.0009 19.4 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 KEG06676.1 - 0.079 12.6 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KEG06676.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF1627 PF07789.12 KEG06676.1 - 0.16 11.6 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) bZIP_1 PF00170.21 KEG06677.1 - 0.013 15.5 0.3 0.013 15.5 0.3 11.3 10 4 3 13 13 13 0 bZIP transcription factor Scm3 PF10384.9 KEG06677.1 - 0.14 11.9 1.7 1.1 9.1 0.1 3.2 3 0 0 3 3 3 0 Centromere protein Scm3 PI_PP_I PF18363.1 KEG06677.1 - 0.42 10.8 12.4 4 7.7 0.1 5.3 4 2 1 5 5 5 0 Phosphoinositide phosphatase insertion domain DUF5093 PF17011.5 KEG06677.1 - 4.1 7.7 7.2 1.1 9.6 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) ERM PF00769.19 KEG06677.1 - 6.1 6.6 108.1 0.38 10.5 15.1 6.2 2 2 3 6 6 6 0 Ezrin/radixin/moesin family Filament PF00038.21 KEG06678.1 - 8.3e-05 22.3 3.7 8.3e-05 22.3 3.7 3.2 1 1 2 3 3 3 1 Intermediate filament protein NAD_binding_11 PF14833.6 KEG06678.1 - 0.11 12.8 0.1 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MORN PF02493.20 KEG06680.1 - 8.7e-18 63.1 18.4 2.8e-07 30.1 0.4 4.8 5 0 0 5 5 5 4 MORN repeat Pkinase PF00069.25 KEG06681.1 - 2.3e-57 194.3 0.0 3.1e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06681.1 - 1.6e-27 96.4 0.0 2.7e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEG06681.1 - 6.6e-07 28.6 0.3 1.1e-06 27.8 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG06681.1 - 0.0001 22.3 0.9 0.0001 22.3 0.9 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG06681.1 - 0.0039 16.6 1.3 0.0039 16.6 1.3 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG06681.1 - 0.05 12.4 0.1 0.078 11.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KEG06681.1 - 0.062 12.9 0.5 0.15 11.6 0.5 1.7 1 0 0 1 1 1 0 RIO1 family MOZ_SAS PF01853.18 KEG06682.1 - 3.3e-27 95.3 0.0 8.7e-27 93.9 0.0 1.7 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEG06682.1 - 0.16 11.6 5.6 0.15 11.7 3.5 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain cNMP_binding PF00027.29 KEG06683.1 - 6.2e-31 106.3 0.1 1.3e-16 60.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Gin PF10764.9 KEG06683.1 - 0.11 12.5 1.5 1 9.3 0.3 2.7 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin MCU PF04678.13 KEG06684.1 - 2.7e-17 63.4 0.1 3.4e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter APG17 PF04108.12 KEG06684.1 - 0.031 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 F-actin_cap_A PF01267.17 KEG06685.1 - 5.4e-27 94.9 0.0 2e-17 63.5 0.0 3.0 2 1 0 2 2 2 2 F-actin capping protein alpha subunit Ribosomal_60s PF00428.19 KEG06685.1 - 2.5 8.8 7.4 0.31 11.7 0.9 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein RRM_1 PF00076.22 KEG06687.1 - 1.7e-18 66.2 0.0 2.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG06687.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aquarius_N PF16399.5 KEG06687.1 - 0.6 8.1 3.1 0.79 7.7 3.1 1.0 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus DUF2477 PF10631.9 KEG06690.1 - 0.036 14.7 0.0 1.1 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) CdvA PF18822.1 KEG06690.1 - 0.05 13.4 0.5 0.14 12.0 0.1 1.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain kleA_kleC PF17383.2 KEG06690.1 - 0.49 10.8 3.2 5.7 7.3 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A PhosphMutase PF10143.9 KEG06696.1 - 1.3e-47 161.8 0.0 1.9e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 KEG06696.1 - 1.3e-17 64.0 0.0 2.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily GAS PF13851.6 KEG06699.1 - 0.0032 16.8 48.8 0.084 12.2 1.7 5.4 2 2 2 5 5 5 5 Growth-arrest specific micro-tubule binding SYCE1 PF15233.6 KEG06699.1 - 0.0048 17.0 5.3 0.0048 17.0 5.3 4.7 3 1 2 5 5 5 1 Synaptonemal complex central element protein 1 ATG16 PF08614.11 KEG06699.1 - 0.005 17.1 4.7 0.005 17.1 4.7 6.0 2 2 4 6 6 6 2 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KEG06699.1 - 0.01 16.0 1.9 0.01 16.0 1.9 4.4 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KEG06699.1 - 0.059 13.9 23.2 0.75 10.3 0.3 5.3 3 2 2 5 5 5 0 Protein of unknown function DUF16 DUF4988 PF16378.5 KEG06699.1 - 3.2 7.4 7.6 0.7 9.5 0.0 3.2 4 1 0 4 4 4 0 Domain of unknown function DUF1664 PF07889.12 KEG06699.1 - 6.1 6.9 21.3 1 9.4 1.1 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Flagellar_rod PF05149.12 KEG06702.1 - 5.2e-110 367.4 29.0 5.2e-110 367.4 29.0 2.0 2 1 0 2 2 2 1 Paraflagellar rod protein UPF0225 PF17775.1 KEG06702.1 - 1.9 9.3 12.4 1.3 9.8 1.7 3.8 3 1 0 3 3 3 0 UPF0225 domain GARP PF16731.5 KEG06705.1 - 0.0063 16.2 11.3 0.0063 16.2 11.3 3.3 1 1 2 3 3 3 1 Glutamic acid/alanine-rich protein of Trypanosoma DUF948 PF06103.11 KEG06705.1 - 0.41 10.9 16.2 0.81 10.0 1.7 4.6 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KEG06705.1 - 1.4 8.9 7.4 6 6.9 2.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF1798 PF08807.10 KEG06705.1 - 3 8.0 6.1 2.4 8.3 2.4 2.6 2 1 1 3 3 3 0 Bacterial domain of unknown function (DUF1798) Laminin_II PF06009.12 KEG06705.1 - 3.1 7.8 26.0 0.34 10.9 0.2 4.2 2 1 3 5 5 5 0 Laminin Domain II Anti-adapt_IraP PF10796.9 KEG06705.1 - 9.5 6.9 8.1 6.2 7.4 0.2 3.4 2 1 2 4 4 4 0 Sigma-S stabilisation anti-adaptor protein Alanine_zipper PF11839.8 KEG06706.1 - 0.016 15.5 11.4 0.016 15.5 11.4 6.2 4 2 1 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein GARP PF16731.5 KEG06706.1 - 0.12 12.0 62.4 0.023 14.4 25.0 4.4 2 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Sec8_exocyst PF04048.14 KEG06706.1 - 9.3 6.1 8.1 3.2 7.7 0.3 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Pput2613-deam PF14427.6 KEG06707.1 - 0.1 12.5 0.1 0.82 9.6 0.0 2.0 2 0 0 2 2 2 0 Pput_2613-like deaminase Syndecan PF01034.20 KEG06708.1 - 0.0035 17.2 0.1 0.0079 16.1 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 KEG06708.1 - 0.0035 18.2 0.0 0.01 16.7 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KEG06708.1 - 0.0039 16.8 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family PTP_tm PF18861.1 KEG06708.1 - 0.013 15.5 3.0 0.015 15.3 0.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J FAM163 PF15069.6 KEG06708.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 FAM163 family YajC PF02699.15 KEG06708.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Adeno_E3_CR2 PF02439.15 KEG06708.1 - 0.06 13.1 2.2 0.16 11.7 2.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAP10 PF07213.11 KEG06708.1 - 0.077 13.0 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 DAP10 membrane protein Orf78 PF06024.12 KEG06708.1 - 0.088 13.1 0.5 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Amnionless PF14828.6 KEG06708.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF4381 PF14316.6 KEG06708.1 - 0.19 12.0 0.1 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SKG6 PF08693.10 KEG06708.1 - 3.1 7.3 6.9 1.9 7.9 3.4 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Symplekin_C PF12295.8 KEG06709.1 - 6.8e-09 36.1 0.1 7.1e-07 29.5 0.0 2.8 2 1 0 2 2 2 2 Symplekin tight junction protein C terminal Vps23_core PF09454.10 KEG06710.1 - 9.9e-11 41.4 0.2 2.1e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 Vps23 core domain Apt1 PF10351.9 KEG06710.1 - 0.00033 19.6 1.3 0.00053 19.0 1.3 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain WASH_WAHD PF11945.8 KEG06710.1 - 0.052 13.1 0.2 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 WAHD domain of WASH complex Vps23_core PF09454.10 KEG06711.1 - 1e-15 57.4 0.1 2.5e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 Vps23 core domain RPN6_N PF18055.1 KEG06711.1 - 0.0017 18.7 0.0 0.056 13.8 0.1 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain DUF1707 PF08044.11 KEG06711.1 - 1.6 8.9 5.4 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Methyltransf_11 PF08241.12 KEG06713.1 - 1.4e-11 44.9 0.0 8.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KEG06713.1 - 3.5e-11 43.1 0.0 7.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KEG06713.1 - 1.5e-10 41.6 0.0 9.7e-07 29.4 0.0 2.7 1 1 2 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 KEG06713.1 - 3e-10 40.2 0.0 3.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG06713.1 - 6.5e-10 39.6 0.0 1.1e-08 35.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KEG06713.1 - 0.0042 16.2 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase NodS PF05401.11 KEG06713.1 - 0.016 14.8 0.0 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) PCMT PF01135.19 KEG06713.1 - 0.053 13.3 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KEG06713.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 KEG06713.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Herpes_LMP1 PF05297.11 KEG06714.1 - 0.0062 15.8 1.5 0.0072 15.6 1.5 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) GATase_4 PF13230.6 KEG06719.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II LRR_4 PF12799.7 KEG06723.1 - 3.5e-07 30.4 6.3 0.053 14.0 0.1 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG06723.1 - 0.00033 20.8 2.1 25 6.0 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 KEG06723.1 - 0.00053 19.7 2.8 0.14 11.9 0.7 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KEG06723.1 - 0.01 15.8 2.2 2 8.6 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Corona_NS3b PF03053.14 KEG06724.1 - 0.094 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein ECM11 PF15463.6 KEG06725.1 - 0.057 14.0 0.3 0.16 12.5 0.3 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 Calc_CGRP_IAPP PF00214.19 KEG06725.1 - 0.086 13.2 0.3 0.086 13.2 0.3 3.5 4 1 0 4 4 4 0 Calcitonin / CGRP / IAPP family TMF_TATA_bd PF12325.8 KEG06725.1 - 0.096 12.9 11.1 3.6 7.8 1.5 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Prp19 PF08606.11 KEG06725.1 - 0.49 10.4 7.2 4.1 7.5 0.0 3.6 3 1 0 3 3 3 0 Prp19/Pso4-like Nup54 PF13874.6 KEG06725.1 - 0.5 10.5 11.6 0.1 12.7 1.0 3.3 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 Filament PF00038.21 KEG06725.1 - 0.68 9.5 11.4 0.91 9.0 2.3 2.9 3 0 0 3 3 3 0 Intermediate filament protein GARP PF16731.5 KEG06725.1 - 2.6 7.7 50.3 2.8 7.6 12.5 4.1 3 1 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma GAS PF13851.6 KEG06725.1 - 2.9 7.2 13.4 4.4 6.6 3.6 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 KEG06725.1 - 3.6 8.3 13.3 9.2 7.0 1.7 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) CHDCT2 PF08074.11 KEG06725.1 - 7.9 6.6 7.5 0.99 9.6 0.3 2.8 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain PP2C_2 PF13672.6 KEG06726.1 - 0.00052 19.7 1.6 0.00052 19.7 1.6 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C Laminin_II PF06009.12 KEG06726.1 - 0.0047 16.9 0.4 0.0093 16.0 0.4 1.4 1 0 0 1 1 1 1 Laminin Domain II ANAPC5 PF12862.7 KEG06726.1 - 2.3 8.3 6.7 7.6 6.7 0.7 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 PDZ_2 PF13180.6 KEG06727.1 - 2.5e-06 27.7 0.0 5.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEG06727.1 - 0.011 16.1 0.0 0.04 14.3 0.0 1.9 1 1 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KEG06727.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Aa_trans PF01490.18 KEG06732.1 - 2.2e-49 168.3 29.7 2.5e-49 168.1 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG06732.1 - 3.8e-06 26.2 10.2 3.8e-06 26.2 10.2 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family MORN PF02493.20 KEG06735.1 - 2.4e-20 71.1 38.8 6.3e-06 25.8 0.5 6.9 7 0 0 7 7 7 6 MORN repeat DUF2568 PF10823.8 KEG06738.1 - 0.049 13.9 0.2 0.071 13.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2568) Peripla_BP_6 PF13458.6 KEG06740.1 - 3.2e-08 33.6 0.2 5.7e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein FPP PF05911.11 KEG06741.1 - 1.1 7.3 37.6 0.023 12.9 17.9 3.0 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil QVR PF17064.5 KEG06741.1 - 1.5 9.1 6.1 27 5.1 0.3 3.4 2 1 1 3 3 3 0 Sleepless protein DUF1664 PF07889.12 KEG06741.1 - 2.1 8.4 13.6 5.1 7.1 0.3 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 KEG06741.1 - 3.1 8.6 23.4 4.6 8.0 3.5 4.2 3 1 2 5 5 5 0 Occludin homology domain FapA PF03961.13 KEG06741.1 - 3.1 6.3 15.8 0.32 9.5 8.5 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A DDE_Tnp_4 PF13359.6 KEG06742.1 - 0.41 10.3 3.9 11 5.7 0.3 2.9 2 0 0 2 2 2 0 DDE superfamily endonuclease Baculo_PEP_C PF04513.12 KEG06742.1 - 0.56 10.2 11.8 0.6 10.2 0.3 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_H PF00075.24 KEG06744.1 - 0.00049 20.3 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 RNase H Peripla_BP_6 PF13458.6 KEG06747.1 - 0.00069 19.4 1.1 0.043 13.5 0.0 2.8 3 0 0 3 3 3 2 Periplasmic binding protein PA26 PF04636.13 KEG06748.1 - 4.3e-31 108.3 0.0 1e-19 70.8 0.1 2.1 2 0 0 2 2 2 2 PA26 p53-induced protein (sestrin) WW PF00397.26 KEG06750.1 - 4e-34 116.4 35.9 1.8e-12 47.1 3.7 4.9 4 1 0 4 4 4 4 WW domain NDT80_PhoG PF05224.12 KEG06750.1 - 0.026 14.7 0.2 0.055 13.7 0.2 1.5 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family SoxD PF04267.12 KEG06750.1 - 0.09 12.9 0.1 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family Cid2 PF09774.9 KEG06750.1 - 3.9 7.9 4.7 70 3.8 0.2 3.3 2 1 1 3 3 3 0 Caffeine-induced death protein 2 Pkinase PF00069.25 KEG06751.1 - 1e-55 189.0 0.0 1.4e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06751.1 - 2.3e-36 125.4 0.0 4.4e-36 124.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06751.1 - 3.8e-06 26.4 0.0 1.7e-05 24.3 0.0 2.0 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KEG06751.1 - 0.03 13.1 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Serglycin PF04360.12 KEG06751.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Serglycin Pkinase PF00069.25 KEG06752.1 - 2.9e-55 187.5 0.0 4e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06752.1 - 8.2e-36 123.6 0.0 1.5e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG06752.1 - 3.1e-06 27.6 0.0 8.8e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 KEG06752.1 - 7.7e-06 25.4 0.0 2e-05 24.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like PH_9 PF15410.6 KEG06752.1 - 0.0014 19.0 0.0 0.0083 16.5 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 KEG06752.1 - 0.0031 17.9 0.0 0.011 16.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DUF1400 PF07176.11 KEG06752.1 - 0.036 14.3 0.1 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PH_4 PF15404.6 KEG06752.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_4 PF12799.7 KEG06753.1 - 9.5e-60 197.5 0.0 0.015 15.7 0.0 20.8 10 6 15 26 26 26 19 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG06753.1 - 3.9e-30 101.3 39.5 2.2 8.5 0.0 23.8 26 0 0 26 26 26 11 Leucine Rich repeat LRR_8 PF13855.6 KEG06753.1 - 3.7e-26 90.7 0.1 3.2 7.6 0.0 15.6 8 6 9 18 18 18 8 Leucine rich repeat Glu-tRNAGln PF02686.15 KEG06753.1 - 7e-12 45.5 0.0 28 5.1 0.0 10.8 11 1 1 12 12 12 0 Glu-tRNAGln amidotransferase C subunit LRR_1 PF00560.33 KEG06753.1 - 1.1e-11 43.5 13.4 1.9e+02 3.2 0.1 16.8 15 6 0 15 15 14 0 Leucine Rich Repeat LRR_9 PF14580.6 KEG06753.1 - 3.2e-07 30.0 22.6 5 6.6 0.1 11.2 5 4 7 13 13 13 3 Leucine-rich repeat LRR_5 PF13306.6 KEG06753.1 - 2.5e-05 24.2 0.0 7.6 6.5 0.0 6.9 4 3 1 6 6 6 1 BspA type Leucine rich repeat region (6 copies) NMU PF02070.15 KEG06753.1 - 0.0064 16.4 7.8 11 6.1 0.0 6.9 9 0 0 9 9 9 1 Neuromedin U DUF1331 PF07048.11 KEG06753.1 - 0.013 15.2 4.4 2.3e+02 1.6 0.0 7.1 9 0 0 9 9 9 0 Protein of unknown function (DUF1331) Kinesin PF00225.23 KEG06753.1 - 0.78 8.6 1.8 35 3.2 0.0 3.7 4 0 0 4 4 4 0 Kinesin motor domain TgMIC1 PF11476.8 KEG06753.1 - 1 9.1 10.2 29 4.4 0.0 7.6 10 0 0 10 10 10 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Motile_Sperm PF00635.26 KEG06754.1 - 1.5e-08 34.5 0.0 5.9e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Lipase_3 PF01764.25 KEG06755.1 - 2.9e-15 56.4 0.0 7.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KEG06755.1 - 0.0032 16.8 0.0 0.0085 15.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEG06755.1 - 0.0089 16.7 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family C1_1 PF00130.22 KEG06755.1 - 0.11 12.5 5.1 1.9 8.4 5.1 2.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF676 PF05057.14 KEG06755.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2630 PF10944.8 KEG06756.1 - 0.086 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DUF4106 PF13388.6 KEG06757.1 - 1.3 8.2 3.5 1.5 8.0 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF2451 PF10474.9 KEG06760.1 - 5.1e-13 49.4 0.0 9.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KEG06760.1 - 2.1e-06 27.3 0.7 4.3e-06 26.2 0.3 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 KEG06760.1 - 0.035 13.0 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DAGK_cat PF00781.24 KEG06760.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF5539 PF17693.1 KEG06765.1 - 0.0066 16.1 2.2 0.0072 16.0 2.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5539) DAHP_synth_1 PF00793.20 KEG06765.1 - 0.069 12.0 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family DnaJ_C PF01556.18 KEG06766.1 - 2.2e-24 86.2 0.0 5.3e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KEG06766.1 - 1.3e-07 31.9 10.8 1.3e-07 31.9 10.8 2.1 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 KEG06766.1 - 0.0046 16.9 14.7 0.13 12.3 2.4 2.9 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KEG06766.1 - 0.16 12.0 6.6 1.2 9.2 1.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 KEG06766.1 - 1.4 8.7 9.8 2.1 8.1 0.7 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-IS66 PF13005.7 KEG06766.1 - 2.5 8.6 13.4 1.2 9.5 0.1 4.5 5 0 0 5 5 5 0 zinc-finger binding domain of transposase IS66 CTP_synth_N PF06418.14 KEG06767.1 - 8.4e-107 356.4 0.0 1.3e-106 355.8 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KEG06767.1 - 5.4e-45 153.5 0.8 3.6e-37 128.0 0.1 2.5 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEG06767.1 - 9.7e-13 48.4 0.7 8.1e-08 32.3 0.1 3.1 3 1 0 3 3 3 2 Peptidase C26 CbiA PF01656.23 KEG06767.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pkinase PF00069.25 KEG06768.1 - 2.7e-54 184.3 0.0 4.3e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06768.1 - 1e-36 126.5 0.0 1.8e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KEG06768.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 2.3 3 0 0 3 3 3 1 PX domain Pkinase_fungal PF17667.1 KEG06768.1 - 0.0019 17.1 0.0 0.0043 15.9 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEG06768.1 - 0.036 13.7 0.1 0.083 12.5 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_Ag35 PF03286.14 KEG06768.1 - 0.04 13.7 5.2 0.096 12.5 5.2 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Kinase-like PF14531.6 KEG06768.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Peptidase_C2 PF00648.21 KEG06769.1 - 6.6e-20 71.3 0.0 9.6e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KEG06769.1 - 1.3e-07 32.0 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III PKcGMP_CC PF16808.5 KEG06769.1 - 0.04 13.8 3.6 0.089 12.7 0.7 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PPO1_DWL PF12142.8 KEG06769.1 - 0.065 13.0 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 Polyphenol oxidase middle domain PI3K_P85_iSH2 PF16454.5 KEG06769.1 - 0.08 12.5 0.7 0.23 11.0 0.7 1.7 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF787 PF05619.11 KEG06769.1 - 0.27 10.3 0.0 2.8 7.0 0.0 2.3 3 0 0 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF787) HisKA_3 PF07730.13 KEG06769.1 - 1 10.0 4.5 7.8 7.1 0.6 3.2 3 0 0 3 3 3 0 Histidine kinase GATase PF00117.28 KEG06771.1 - 1.2e-29 103.4 0.0 2.6e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KEG06771.1 - 2.5e-17 62.7 0.0 8e-08 32.2 0.0 2.9 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 KEG06771.1 - 1.9e-13 50.7 0.0 6.1e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KEG06771.1 - 3.1e-09 36.3 0.0 5.2e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 KEG06771.1 - 7e-06 25.7 0.0 0.00039 20.0 0.0 2.5 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KEG06771.1 - 0.00016 21.4 0.0 0.00095 18.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 KEG06771.1 - 0.00048 19.5 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 KEG06771.1 - 0.0056 16.5 0.0 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.16 KEG06771.1 - 0.0077 15.1 0.1 0.038 12.8 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 KEG06771.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family GP79 PF17463.2 KEG06771.1 - 0.043 13.8 0.6 0.14 12.1 0.6 1.9 1 0 0 1 1 1 0 Gene product 79 Asn_synthase PF00733.21 KEG06771.1 - 0.058 13.1 0.2 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Asparagine synthase Dak2 PF02734.17 KEG06771.1 - 0.066 13.1 0.3 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 DAK2 domain Inhibitor_I68 PF10468.9 KEG06773.1 - 0.15 12.4 0.9 4.3 7.8 0.4 2.1 1 1 1 2 2 2 0 Carboxypeptidase inhibitor I68 DUF5403 PF17395.2 KEG06773.1 - 0.17 12.2 1.5 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Peptidase_M8 PF01457.16 KEG06775.1 - 2.1e-110 370.0 0.3 2.6e-110 369.6 0.3 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF1935 PF09149.10 KEG06776.1 - 3.6e-25 88.3 0.0 4.3e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 KEG06777.1 - 2.2e-26 92.6 0.0 3.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG06777.1 - 7e-18 64.9 0.0 2.1e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Sacchrp_dh_NADP PF03435.18 KEG06777.1 - 0.054 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-HIT PF04438.16 KEG06778.1 - 1.4e-06 28.0 9.2 2.9e-06 27.0 9.2 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KEG06778.1 - 0.0052 16.8 5.6 0.011 15.8 5.6 1.6 1 0 0 1 1 1 1 MYND finger XRCC4 PF06632.12 KEG06778.1 - 0.051 12.4 0.1 0.07 12.0 0.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Adaptin_N PF01602.20 KEG06779.1 - 1.9e-91 307.2 0.3 2.4e-91 306.9 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEG06779.1 - 1.1e-28 100.4 0.1 3.1e-27 95.6 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEG06779.1 - 4.5e-09 36.6 9.8 0.035 14.5 0.7 5.3 4 1 1 5 5 5 4 HEAT repeats CLASP_N PF12348.8 KEG06779.1 - 0.00037 20.1 0.2 0.23 11.0 0.0 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KEG06779.1 - 0.00053 20.0 6.7 0.83 10.1 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KEG06779.1 - 0.012 16.2 1.6 13 6.5 0.0 4.7 3 1 1 4 4 4 0 HEAT-like repeat RICTOR_V PF14668.6 KEG06779.1 - 0.012 15.8 0.0 0.12 12.6 0.0 2.7 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 ChitinaseA_N PF08329.10 KEG06784.1 - 0.16 11.6 0.2 0.33 10.6 0.1 1.4 1 1 0 1 1 1 0 Chitinase A, N-terminal domain WD40 PF00400.32 KEG06785.1 - 3.5e-46 154.2 34.9 2.7e-08 34.4 1.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG06785.1 - 3.9e-06 27.1 1.1 0.12 12.7 0.0 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEG06785.1 - 4.6e-06 25.6 13.9 0.32 9.6 0.1 5.1 3 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KEG06785.1 - 2.1e-05 24.5 1.9 0.0071 16.2 0.1 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KEG06785.1 - 0.00022 20.7 0.2 0.48 9.7 0.1 3.5 2 1 2 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KEG06785.1 - 0.02 13.9 9.5 0.35 9.8 0.7 3.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FKBP_N PF01346.18 KEG06785.1 - 0.42 11.6 5.7 1.9 9.5 1.1 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PH PF00169.29 KEG06786.1 - 4.9e-11 43.1 0.1 1.1e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KEG06786.1 - 0.0021 18.5 1.7 0.028 14.9 0.6 2.8 2 2 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KEG06786.1 - 0.007 16.7 2.0 0.014 15.7 0.1 2.3 3 1 1 4 4 4 1 Pleckstrin homology domain DUF3525 PF12039.8 KEG06786.1 - 0.012 14.4 0.8 0.016 14.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) DUF1664 PF07889.12 KEG06786.1 - 0.091 12.8 7.4 0.056 13.5 4.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Kre28 PF17097.5 KEG06786.1 - 0.098 11.6 7.0 0.084 11.8 5.8 1.4 1 1 0 1 1 1 0 Spindle pole body component DUF334 PF03904.13 KEG06786.1 - 0.12 11.9 3.0 0.17 11.4 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Spc7 PF08317.11 KEG06786.1 - 0.13 11.1 13.3 0.08 11.8 9.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein MIP-T3_C PF17749.1 KEG06786.1 - 0.3 11.0 9.7 0.58 10.1 9.7 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Atg14 PF10186.9 KEG06786.1 - 0.38 9.8 9.5 0.52 9.3 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KEG06786.1 - 0.63 10.1 7.9 0.91 9.6 7.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 KEG06786.1 - 1.2 9.2 6.7 4.7 7.2 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Seryl_tRNA_N PF02403.22 KEG06786.1 - 2.2 8.6 11.2 2.2 8.5 9.7 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Troponin PF00992.20 KEG06786.1 - 2.7 8.3 16.5 1.7 8.9 12.7 2.3 1 1 2 3 3 3 0 Troponin NuA4 PF09340.10 KEG06788.1 - 9.2e-14 51.1 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 HpaB PF03241.13 KEG06789.1 - 0.061 12.4 0.1 0.11 11.6 0.1 1.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal EF-hand_1 PF00036.32 KEG06795.1 - 7.4e-07 28.3 0.7 3.1e-06 26.4 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KEG06795.1 - 2.6e-06 26.9 1.0 1.3e-05 24.7 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KEG06795.1 - 3.1e-06 27.6 0.1 5.7e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KEG06795.1 - 2.3e-05 23.7 0.5 0.00013 21.3 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KEG06795.1 - 0.00014 21.6 0.1 0.0011 18.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair YidD PF01809.18 KEG06797.1 - 0.0049 16.7 0.2 0.0092 15.8 0.2 1.4 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor AAA_16 PF13191.6 KEG06800.1 - 2.7e-05 24.6 0.0 6.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KEG06800.1 - 3.6e-05 24.3 0.0 0.001 19.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEG06800.1 - 0.0067 16.8 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) mRNA_cap_C PF03919.15 KEG06800.1 - 0.0069 17.0 0.0 0.022 15.4 0.0 1.9 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain AAA_17 PF13207.6 KEG06800.1 - 0.024 15.1 0.1 0.024 15.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KEG06800.1 - 0.042 13.3 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 KEG06800.1 - 2.3 7.9 5.1 2.2 7.9 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase OrfB_Zn_ribbon PF07282.11 KEG06800.1 - 4.2 7.4 11.0 3.6 7.6 3.0 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Urocanase PF01175.18 KEG06801.1 - 2.6e-85 285.4 0.0 3.8e-85 284.8 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 KEG06801.1 - 2.9e-83 278.1 0.2 4.8e-72 241.5 0.1 2.3 1 1 1 2 2 2 2 Urocanase C-terminal domain Urocanase_N PF17391.2 KEG06801.1 - 2.1e-54 182.6 0.4 3.2e-53 178.8 0.1 2.3 2 0 0 2 2 2 1 Urocanase N-terminal domain Complex1_LYR_1 PF13232.6 KEG06803.1 - 6.3e-59 196.6 10.9 2.5e-50 169.0 2.9 2.3 1 1 1 2 2 2 2 Complex1_LYR-like Complex1_LYR PF05347.15 KEG06803.1 - 1.7e-05 24.8 2.1 2.8e-05 24.1 0.3 2.3 1 1 1 2 2 2 1 Complex 1 protein (LYR family) DUF4771 PF15995.5 KEG06803.1 - 0.00066 20.0 0.1 0.0016 18.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4771) NEMO PF11577.8 KEG06803.1 - 0.15 12.1 4.5 0.33 11.0 4.5 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO PCP_red PF08369.10 KEG06803.1 - 0.2 11.9 1.0 8.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit PET117 PF15786.5 KEG06803.1 - 2.9 8.2 7.3 25 5.2 4.0 2.8 2 1 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial ATP_bind_1 PF03029.17 KEG06805.1 - 1.1e-66 225.1 0.0 1.3e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KEG06805.1 - 1e-06 29.2 0.0 2.9e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KEG06805.1 - 4e-06 26.9 0.0 5.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KEG06805.1 - 6.1e-06 26.1 0.0 9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEG06805.1 - 3e-05 23.7 0.0 0.00063 19.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 KEG06805.1 - 3.6e-05 23.4 0.0 0.00029 20.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KEG06805.1 - 0.00033 20.1 0.0 0.63 9.4 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 KEG06805.1 - 0.00063 19.9 1.0 0.00081 19.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 KEG06805.1 - 0.00088 18.3 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 KEG06805.1 - 0.0014 18.2 0.0 0.061 12.8 0.0 2.5 3 0 0 3 3 2 1 Ferrous iron transport protein B cobW PF02492.19 KEG06805.1 - 0.0026 17.4 1.5 0.028 14.0 1.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 KEG06805.1 - 0.0039 16.5 0.0 0.024 13.9 0.0 2.0 1 1 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KEG06805.1 - 0.0044 16.9 0.0 3.4 7.5 0.0 3.1 4 0 0 4 4 3 1 RsgA GTPase Zeta_toxin PF06414.12 KEG06805.1 - 0.0066 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 KEG06805.1 - 0.008 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KEG06805.1 - 0.0086 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 KEG06805.1 - 0.0087 15.5 0.0 0.081 12.4 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.6 KEG06805.1 - 0.0092 16.3 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KEG06805.1 - 0.011 15.5 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 KEG06805.1 - 0.011 15.6 0.0 0.25 11.1 0.0 2.2 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KEG06805.1 - 0.012 15.4 0.6 0.025 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEG06805.1 - 0.016 15.1 0.1 0.037 13.9 0.1 1.5 1 1 0 1 1 1 0 NTPase NACHT PF05729.12 KEG06805.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KEG06805.1 - 0.022 15.1 0.1 0.036 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG06805.1 - 0.03 14.9 0.8 0.094 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KEG06805.1 - 0.037 14.2 0.0 0.19 11.9 0.0 2.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KEG06805.1 - 0.049 13.6 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 KEG06805.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KEG06805.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KEG06805.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEG06805.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MA3 PF02847.17 KEG06806.1 - 4.8e-14 52.3 0.4 9.4e-14 51.4 0.4 1.5 1 0 0 1 1 1 1 MA3 domain TEX19 PF15553.6 KEG06806.1 - 0.3 11.0 5.5 0.25 11.3 3.5 1.8 2 0 0 2 2 2 0 Testis-expressed protein 19 TERB2 PF15101.6 KEG06806.1 - 0.4 10.7 6.9 0.66 10.0 6.9 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4578 PF15147.6 KEG06806.1 - 0.46 11.4 5.4 0.91 10.4 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) DUF3886 PF13025.6 KEG06806.1 - 0.56 10.4 16.8 1.4 9.2 9.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) Kinesin PF00225.23 KEG06807.1 - 2.7e-27 95.6 5.8 1.4e-23 83.3 0.0 3.5 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KEG06807.1 - 8.4e-09 35.5 0.8 4.4e-08 33.2 0.0 2.5 2 1 1 3 3 3 1 Microtubule binding FPP PF05911.11 KEG06807.1 - 0.07 11.3 44.0 0.11 10.6 43.7 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Ribosomal_L26 PF16906.5 KEG06807.1 - 0.56 10.7 7.2 8.4 6.9 0.4 2.9 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Mucin PF01456.17 KEG06809.1 - 1.2e-10 41.5 12.0 1.6e-10 41.1 12.0 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Shisa PF13908.6 KEG06809.1 - 2.3 8.4 8.5 6.4 7.0 8.5 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Totivirus_coat PF05518.11 KEG06809.1 - 6.7 4.6 9.2 6.9 4.6 9.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_M8 PF01457.16 KEG06810.1 - 9.7e-39 133.4 0.1 1.1e-38 133.3 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Choline_kinase PF01633.20 KEG06812.1 - 2.7e-21 76.2 1.5 2.3e-20 73.1 1.5 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KEG06812.1 - 6.1e-11 42.7 0.5 3.8e-10 40.1 0.5 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KEG06812.1 - 0.0047 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 KEG06812.1 - 0.0086 15.4 0.6 0.014 14.7 0.6 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase WD40 PF00400.32 KEG06815.1 - 1.2e-65 215.8 17.8 1.7e-08 34.9 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG06815.1 - 9.3e-21 73.9 2.9 4e-05 23.8 0.1 6.5 1 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KEG06815.1 - 1.3e-11 44.4 4.2 0.035 13.4 0.0 6.4 4 3 3 7 7 7 4 WD40-like domain Nup160 PF11715.8 KEG06815.1 - 1.2e-09 37.4 16.2 0.053 12.2 0.1 6.6 1 1 5 7 7 7 4 Nucleoporin Nup120/160 eIF2A PF08662.11 KEG06815.1 - 3.5e-07 30.3 6.3 0.0043 17.0 0.2 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A CEP19 PF14933.6 KEG06815.1 - 0.034 14.5 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein Ge1_WD40 PF16529.5 KEG06815.1 - 0.14 11.1 13.9 4.4 6.2 2.7 4.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein UPF0506 PF11703.8 KEG06815.1 - 5.4 7.5 6.7 27 5.2 0.8 3.7 3 1 1 4 4 4 0 UPF0506 Mito_carr PF00153.27 KEG06816.1 - 2.8e-67 222.7 6.7 1e-24 86.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PPR PF01535.20 KEG06816.1 - 0.0047 17.1 0.1 7.5 7.0 0.0 3.0 2 0 0 2 2 2 2 PPR repeat Fuseless PF15993.5 KEG06816.1 - 0.04 13.1 1.3 0.065 12.4 0.4 1.7 2 0 0 2 2 2 0 Fuseless polyprenyl_synt PF00348.17 KEG06817.1 - 2.6e-53 180.7 0.0 3.5e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.11 KEG06817.1 - 8.8e-18 65.5 0.0 3e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 KEG06817.1 - 8.5e-15 55.2 0.0 1.7e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain zf-CCCH PF00642.24 KEG06818.1 - 1.1e-06 28.3 2.1 3.6e-06 26.7 2.1 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG06818.1 - 2.4e-05 24.0 2.6 5e-05 23.0 2.6 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KEG06818.1 - 4.5e-05 24.1 1.7 4.5e-05 24.1 1.7 2.2 3 0 0 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 KEG06818.1 - 5.8e-05 23.0 7.5 0.00014 21.8 7.5 1.7 1 0 0 1 1 1 1 Zinc finger domain His_Phos_1 PF00300.22 KEG06820.1 - 2.6e-32 112.1 0.3 4e-25 88.6 0.1 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 KEG06820.1 - 4.7e-19 68.6 4.2 3.8e-12 46.0 0.0 3.5 2 1 1 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.6 KEG06820.1 - 0.003 17.7 0.1 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain CCD PF07860.11 KEG06820.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 WisP family C-Terminal Region PGA2 PF07543.12 KEG06820.1 - 6.6 6.7 6.9 3.7 7.5 0.1 2.8 3 0 0 3 3 3 0 Protein trafficking PGA2 Amnionless PF14828.6 KEG06821.1 - 0.084 11.7 0.1 0.089 11.6 0.1 1.0 1 0 0 1 1 1 0 Amnionless DUF4636 PF15468.6 KEG06821.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) PepSY_TM PF03929.16 KEG06821.1 - 0.16 11.6 0.3 0.4 10.3 0.0 1.5 1 1 1 2 2 2 0 PepSY-associated TM region Mucin PF01456.17 KEG06826.1 - 2.1e-09 37.5 48.5 0.00017 21.6 13.7 3.2 2 1 0 2 2 2 2 Mucin-like glycoprotein Mucin PF01456.17 KEG06827.1 - 0.083 12.9 54.3 0.12 12.4 38.5 3.3 1 1 1 2 2 2 0 Mucin-like glycoprotein DUF812 PF05667.11 KEG06828.1 - 0.011 14.7 18.5 0.013 14.4 18.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MCC-bdg_PDZ PF10506.9 KEG06828.1 - 0.021 14.8 18.7 0.43 10.6 3.2 3.0 1 1 2 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GAS PF13851.6 KEG06828.1 - 0.12 11.7 32.5 0.2 11.0 11.9 2.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KEG06828.1 - 0.27 11.7 27.0 6.6 7.1 26.1 2.0 1 1 0 1 1 1 0 Fez1 Mod_r PF07200.13 KEG06828.1 - 0.36 10.9 22.3 0.58 10.2 22.3 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AAA_11 PF13086.6 KEG06828.1 - 0.56 10.0 8.2 0.86 9.3 8.2 1.3 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 KEG06828.1 - 0.6 10.5 25.6 1.6 9.1 3.0 3.4 1 1 3 4 4 4 0 Csm1 N-terminal domain FapA PF03961.13 KEG06828.1 - 0.67 8.5 10.3 0.86 8.1 10.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Golgin_A5 PF09787.9 KEG06828.1 - 0.75 9.2 19.3 0.92 8.9 19.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 KEG06828.1 - 1.5 9.4 28.5 0.71 10.5 19.2 2.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rootletin PF15035.6 KEG06828.1 - 1.7 8.6 30.3 0.58 10.2 8.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion PorB PF11565.8 KEG06828.1 - 2.3 8.7 12.0 0.47 10.9 3.9 2.4 1 1 1 2 2 2 0 Alpha helical Porin B FAD-SLDH PF12318.8 KEG06828.1 - 2.9 8.0 5.2 5 7.2 5.2 1.5 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4407 PF14362.6 KEG06828.1 - 5.3 6.3 19.5 7.5 5.8 19.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 KEG06828.1 - 6.2 6.6 41.7 6 6.6 38.8 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.9 KEG06828.1 - 8.7 5.3 22.7 6.1 5.8 21.5 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEG06829.1 - 0.0015 17.5 38.9 0.0019 17.2 22.9 2.6 1 1 1 2 2 2 1 Spc7 kinetochore protein EzrA PF06160.12 KEG06829.1 - 0.0093 14.2 30.4 0.33 9.1 0.0 3.4 2 1 1 3 3 3 2 Septation ring formation regulator, EzrA CEP63 PF17045.5 KEG06829.1 - 0.063 13.2 38.4 0.22 11.4 0.3 3.5 1 1 3 4 4 4 0 Centrosomal protein of 63 kDa HMMR_N PF15905.5 KEG06829.1 - 0.24 10.8 36.4 0.33 10.4 7.4 3.1 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal H-kinase_dim PF02895.14 KEG06829.1 - 0.27 11.6 12.0 2.9 8.4 2.3 3.1 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain AAA_13 PF13166.6 KEG06829.1 - 0.46 9.1 27.7 0.0068 15.1 11.9 2.1 1 1 1 2 2 2 0 AAA domain Filament PF00038.21 KEG06829.1 - 0.48 10.0 36.1 10 5.6 0.8 3.2 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 KEG06829.1 - 0.54 10.3 19.1 0.45 10.6 1.0 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KEG06829.1 - 0.6 10.4 6.9 6 7.2 0.1 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.20 KEG06829.1 - 0.6 9.4 50.8 5 6.4 41.7 2.4 1 1 1 2 2 2 0 Tropomyosin ATG16 PF08614.11 KEG06829.1 - 0.73 10.0 40.4 8.6 6.5 16.3 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KEG06829.1 - 0.95 8.5 25.3 3.7 6.5 18.1 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 KEG06829.1 - 1.1 9.5 38.6 0.035 14.3 9.7 4.0 1 1 3 4 4 4 0 Flagellar FliJ protein HrpB7 PF09486.10 KEG06829.1 - 1.3 9.4 41.3 1.2 9.5 2.1 3.9 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 KEG06829.1 - 1.4 9.1 16.2 3 8.0 3.3 3.5 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KEG06829.1 - 1.8 8.6 27.5 1 9.5 1.8 4.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.8 KEG06829.1 - 2 5.8 38.8 3.2 5.2 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Laminin_I PF06008.14 KEG06829.1 - 2.3 7.9 36.1 11 5.7 0.3 4.0 1 1 3 4 4 4 0 Laminin Domain I Seryl_tRNA_N PF02403.22 KEG06829.1 - 3.2 8.0 33.1 0.95 9.7 7.4 4.3 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KEG06829.1 - 3.7 6.8 28.7 97 2.2 16.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KEG06829.1 - 3.9 6.9 39.2 1 8.8 23.1 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KEG06829.1 - 4.5 7.3 10.6 6.1 6.9 0.1 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAP65_ASE1 PF03999.12 KEG06829.1 - 5.1 5.7 26.0 5.7e+02 -1.1 26.0 2.5 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Katanin_con80 PF13925.6 KEG06829.1 - 7.2 6.6 9.3 5.2 7.1 6.4 2.4 1 1 1 2 2 2 0 con80 domain of Katanin DUF4208 PF13907.6 KEG06829.1 - 8.2 6.9 8.4 8 7.0 0.2 4.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4208) Pkinase PF00069.25 KEG06830.1 - 1.3e-22 80.4 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06830.1 - 2.2e-10 40.2 0.0 3.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG06830.1 - 5.9e-06 25.3 0.1 7.7e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG06830.1 - 0.0023 17.3 0.1 0.0049 16.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG06830.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 KEG06831.1 - 2.1e-30 104.4 0.0 3.4e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG06831.1 - 0.0002 20.9 0.0 0.00053 19.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG06831.1 - 0.0064 16.6 0.0 0.085 13.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif PHM7_cyt PF14703.6 KEG06831.1 - 0.016 15.5 0.0 8.4 6.6 0.0 2.7 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter BRF1 PF07741.13 KEG06831.1 - 0.089 13.1 1.3 0.2 12.0 0.3 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Pkinase PF00069.25 KEG06832.1 - 5.6e-63 212.8 0.0 1e-62 211.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06832.1 - 4.2e-37 127.8 0.0 2.6e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG06832.1 - 0.00013 21.4 0.2 0.04 13.2 0.1 2.8 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEG06832.1 - 0.00064 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG06832.1 - 0.0041 16.0 0.0 0.0054 15.6 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEG06832.1 - 0.015 14.9 0.0 0.9 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KEG06832.1 - 0.021 14.8 3.1 0.048 13.6 3.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG06832.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Peptidase_M8 PF01457.16 KEG06833.1 - 1.3e-111 373.9 3.8 2.4e-59 201.5 2.6 2.3 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG06833.1 - 0.0075 16.4 0.1 0.0075 16.4 0.1 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 YkyA PF10368.9 KEG06836.1 - 0.13 11.9 0.6 0.21 11.2 0.6 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein HisKA_3 PF07730.13 KEG06836.1 - 1.3 9.6 16.3 6.4 7.4 2.2 4.3 2 1 2 4 4 4 0 Histidine kinase DUF463 PF04317.12 KEG06836.1 - 9 5.1 7.6 0.77 8.6 2.7 1.7 2 0 0 2 2 2 0 YcjX-like family, DUF463 Mucin PF01456.17 KEG06837.1 - 1.2e-11 44.7 7.8 1.2e-11 44.7 7.8 4.2 1 1 2 3 3 3 1 Mucin-like glycoprotein UPF0242 PF06785.11 KEG06837.1 - 0.15 12.2 1.9 0.4 10.8 1.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KEG06837.1 - 1 9.4 11.5 0.43 10.6 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mit_KHE1 PF10173.9 KEG06837.1 - 1.2 9.2 11.7 1.2 9.2 1.4 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Sec20 PF03908.13 KEG06837.1 - 3 7.8 5.4 1.6 8.7 0.4 2.7 2 1 1 3 3 3 0 Sec20 Fib_alpha PF08702.10 KEG06837.1 - 5 7.3 7.7 9.2 6.4 4.2 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KEG06837.1 - 6.1 7.2 17.9 11 6.4 7.8 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) BAR_2 PF10455.9 KEG06837.1 - 7.7 5.6 15.8 0.32 10.1 3.7 2.3 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mucin PF01456.17 KEG06838.1 - 1.8e-09 37.7 43.2 4.9e-06 26.6 14.3 2.9 2 1 0 2 2 2 2 Mucin-like glycoprotein MetallophosN PF16371.5 KEG06838.1 - 0.091 13.0 0.3 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase JAB PF01398.21 KEG06839.1 - 9.9e-10 38.4 0.1 6.9e-09 35.7 0.1 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KEG06839.1 - 3.3e-09 37.1 0.2 5.9e-09 36.3 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0121 PF03661.13 KEG06839.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) BT1 PF03092.16 KEG06840.1 - 1.7e-208 693.1 5.9 2.1e-208 692.8 5.9 1.0 1 0 0 1 1 1 1 BT1 family DUF4173 PF13777.6 KEG06840.1 - 3.2 7.1 15.4 0.37 10.2 4.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4173) TMEM65 PF10507.9 KEG06841.1 - 1.2e-33 115.3 3.0 1.2e-33 115.3 3.0 1.9 2 0 0 2 2 2 1 Transmembrane protein 65 FliS_cochap PF16522.5 KEG06841.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 EF-hand_1 PF00036.32 KEG06841.1 - 0.22 11.1 0.0 0.6 9.8 0.0 1.7 2 0 0 2 2 2 0 EF hand Dpy-30 PF05186.13 KEG06842.1 - 5.5e-08 32.4 0.2 8.4e-08 31.8 0.2 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF349 PF03993.12 KEG06842.1 - 0.017 15.4 2.8 0.017 15.4 2.8 3.4 2 2 1 3 3 3 0 Domain of Unknown Function (DUF349) FLYWCH_N PF15423.6 KEG06842.1 - 0.026 14.6 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein YqhG PF11079.8 KEG06842.1 - 0.083 11.8 2.1 0.13 11.2 2.1 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Cpn60_TCP1 PF00118.24 KEG06843.1 - 1.7e-147 492.0 9.5 1.9e-147 491.8 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.21 KEG06844.1 - 1.6e-39 135.7 24.4 4e-39 134.4 16.6 2.4 2 1 0 2 2 2 2 Cation efflux family DUF4407 PF14362.6 KEG06846.1 - 0.0033 16.8 8.2 0.0033 16.8 8.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) HTH_23 PF13384.6 KEG06846.1 - 0.0065 16.2 1.6 0.037 13.8 0.3 2.6 2 0 0 2 2 2 1 Homeodomain-like domain Spc7 PF08317.11 KEG06846.1 - 0.0089 14.9 9.8 0.049 12.5 3.6 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein HMMR_N PF15905.5 KEG06846.1 - 0.0098 15.4 7.1 0.58 9.6 0.2 2.4 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 KEG06846.1 - 0.014 15.6 9.7 0.14 12.4 3.2 2.8 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 KEG06846.1 - 0.015 14.6 12.1 0.33 10.3 5.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1418 PF07214.12 KEG06846.1 - 0.027 14.3 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) CENP-F_leu_zip PF10473.9 KEG06846.1 - 0.033 14.2 16.2 0.039 14.0 0.5 3.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Androgen_recep PF02166.16 KEG06846.1 - 0.1 11.4 9.6 0.083 11.7 1.5 2.2 2 0 0 2 2 2 0 Androgen receptor DUF4088 PF13317.6 KEG06846.1 - 0.11 12.1 6.0 0.017 14.7 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) Spc29 PF17082.5 KEG06846.1 - 0.15 11.9 5.6 0.083 12.7 2.5 1.9 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF641 PF04859.12 KEG06846.1 - 0.23 11.8 9.1 0.4 11.0 0.6 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HTH_28 PF13518.6 KEG06846.1 - 0.37 11.0 3.6 5.2 7.3 0.6 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 KEG06846.1 - 0.42 10.5 2.5 30 4.6 0.2 3.2 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB KORA PF16509.5 KEG06846.1 - 0.42 10.9 3.0 17 5.8 1.1 2.4 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor DUF1515 PF07439.11 KEG06846.1 - 1.6 8.8 4.3 0.84 9.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DegT_DnrJ_EryC1 PF01041.17 KEG06846.1 - 2 7.7 7.5 6.7 5.9 1.7 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family TMF_DNA_bd PF12329.8 KEG06846.1 - 3.5 7.7 10.4 2.6 8.1 0.1 3.6 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.25 KEG06847.1 - 8.2e-62 209.0 0.0 1.3e-61 208.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06847.1 - 2e-25 89.5 0.0 2.8e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG06847.1 - 0.00041 19.8 0.0 0.00099 18.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEG06847.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM199X PF15814.5 KEG06848.1 - 0.42 9.6 4.7 0.49 9.4 4.7 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF383 PF04063.14 KEG06851.1 - 1.3e-10 41.3 0.0 5e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF383) 14-3-3 PF00244.20 KEG06851.1 - 0.0028 17.2 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 14-3-3 protein HEAT_2 PF13646.6 KEG06851.1 - 0.0049 17.2 0.8 1.5 9.2 0.0 3.8 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KEG06851.1 - 0.048 13.9 0.9 15 6.2 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat DUF4223 PF13978.6 KEG06851.1 - 0.11 12.5 0.1 22 5.1 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4223) Toxin_25 PF08095.11 KEG06851.1 - 4.6 7.3 9.8 11 6.1 0.9 2.7 2 0 0 2 2 2 0 Hefutoxin family PPV_E1_C PF00519.17 KEG06852.1 - 0.16 10.7 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF1935 PF09149.10 KEG06853.1 - 2.9e-35 120.7 0.2 3e-25 88.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1935) DUF5348 PF17295.2 KEG06853.1 - 9.2e-05 22.3 1.7 0.027 14.4 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5348) RMI1_N PF08585.12 KEG06854.1 - 7.4e-22 78.2 0.0 1.2e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein BRCA-2_OB1 PF09103.10 KEG06854.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.6 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Steroid_dh PF02544.16 KEG06855.1 - 6.6e-23 81.4 0.3 1.2e-22 80.5 0.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEG06855.1 - 0.0042 16.6 0.1 0.0062 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PSI_PsaH PF03244.14 KEG06855.1 - 0.13 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Cation_ATPase_C PF00689.21 KEG06856.1 - 1.7e-39 135.4 6.2 4.1e-39 134.2 6.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEG06856.1 - 4.3e-30 104.6 0.6 4.3e-30 104.6 0.6 2.2 2 1 1 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KEG06856.1 - 5.9e-15 54.7 0.0 1.3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KEG06856.1 - 9.5e-14 52.2 0.1 3.3e-10 40.6 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEG06856.1 - 1.8e-11 43.9 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEG06856.1 - 5.2e-06 26.4 0.1 0.0004 20.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4870 PF09685.10 KEG06856.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4870) DUF2757 PF10955.8 KEG06857.1 - 0.0021 18.2 1.6 0.0054 17.0 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) V_ATPase_I PF01496.19 KEG06857.1 - 0.011 13.7 15.4 0.014 13.4 15.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TT1725 PF18324.1 KEG06857.1 - 0.045 13.8 0.3 0.12 12.4 0.2 1.8 1 1 0 1 1 1 0 Hypothetical protein TT1725 SKA2 PF16740.5 KEG06857.1 - 0.42 10.4 27.6 0.051 13.4 7.3 3.3 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Sec34 PF04136.15 KEG06857.1 - 0.54 10.1 13.5 0.17 11.8 7.6 2.6 1 1 1 3 3 3 0 Sec34-like family Pkip-1 PF06878.11 KEG06857.1 - 1.8 8.6 14.2 0.13 12.4 2.7 2.4 1 1 0 2 2 2 0 Pkip-1 protein NPV_P10 PF05531.12 KEG06857.1 - 1.9 9.0 12.9 1.8e+02 2.7 9.9 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C4pol PF14260.6 KEG06857.1 - 4.6 7.8 7.1 3.4 8.2 0.7 2.9 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta ABATE PF07336.11 KEG06857.1 - 5.6 7.6 9.1 21 5.8 9.1 2.0 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Peptidase_S10 PF00450.22 KEG06857.1 - 6.8 6.0 8.4 9.1 5.6 8.4 1.3 1 1 0 1 1 1 0 Serine carboxypeptidase Jnk-SapK_ap_N PF09744.9 KEG06857.1 - 9.1 6.5 38.0 0.17 12.1 17.5 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 GARP PF16731.5 KEG06862.1 - 0.029 14.1 7.0 0.061 13.0 6.9 1.6 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Mucin PF01456.17 KEG06863.1 - 9.5e-05 22.4 0.4 9.5e-05 22.4 0.4 3.4 3 1 0 3 3 3 1 Mucin-like glycoprotein Alanine_zipper PF11839.8 KEG06864.1 - 0.032 14.6 23.1 0.032 14.6 23.1 5.5 4 1 1 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein GARP PF16731.5 KEG06864.1 - 0.061 13.0 62.6 0.11 12.1 23.6 3.2 2 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Pkinase PF00069.25 KEG06865.1 - 6.3e-32 111.0 0.0 5.6e-28 98.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06865.1 - 1.3e-20 73.8 0.0 1.9e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG06865.1 - 9.9e-07 28.9 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG06865.1 - 0.00012 21.0 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KEG06866.1 - 4.9e-49 167.1 0.0 8.6e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG06866.1 - 2.3e-27 95.9 0.0 1.5e-26 93.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEG06866.1 - 0.0021 17.4 0.1 0.0038 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG06866.1 - 0.0033 17.4 0.2 0.017 15.1 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3543 PF12063.8 KEG06866.1 - 0.0091 15.4 0.2 0.21 10.9 0.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 KEG06866.1 - 0.011 14.6 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Alanine_zipper PF11839.8 KEG06868.1 - 0.0051 17.2 74.0 0.16 12.3 7.9 5.6 4 1 1 5 5 5 5 Alanine-zipper, major outer membrane lipoprotein Tubulin_C PF03953.17 KEG06868.1 - 0.085 13.0 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 Tubulin C-terminal domain XhlA PF10779.9 KEG06868.1 - 0.28 11.4 14.2 2 8.7 0.4 4.1 3 1 0 3 3 3 0 Haemolysin XhlA FLgD_tudor PF13861.6 KEG06868.1 - 0.53 10.6 2.7 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 FlgD Tudor-like domain SBDS_C PF09377.10 KEG06868.1 - 1 9.4 9.9 60 3.7 0.1 3.9 2 2 0 2 2 2 0 SBDS protein C-terminal domain MCPsignal PF00015.21 KEG06868.1 - 1.1 9.0 31.3 0.16 11.8 7.9 4.1 2 2 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PP2C PF00481.21 KEG06871.1 - 1e-55 189.1 0.0 1.6e-55 188.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KEG06871.1 - 0.021 14.4 0.0 0.055 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C FYVE PF01363.21 KEG06872.1 - 2.6e-14 53.1 11.2 9.4e-14 51.3 11.2 2.0 1 1 0 1 1 1 1 FYVE zinc finger Elf1 PF05129.13 KEG06872.1 - 0.23 11.5 4.3 0.77 9.9 4.3 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CPSase_L_D2 PF02786.17 KEG06873.1 - 9.6e-49 165.7 0.2 2.1e-48 164.6 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.12 KEG06873.1 - 1.8e-30 105.8 0.0 1.4e-16 60.0 0.3 3.3 3 1 0 3 3 3 2 Acetyl-CoA carboxylase, central region Biotin_carb_N PF00289.22 KEG06873.1 - 6e-28 97.6 0.0 1.4e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEG06873.1 - 8.2e-21 74.1 0.0 1.5e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEG06873.1 - 5.9e-10 38.8 0.1 1.6e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KEG06873.1 - 1.5e-07 31.2 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEG06873.1 - 0.00021 20.9 0.3 0.00052 19.6 0.3 1.5 1 1 0 1 1 1 1 ATP-grasp domain Myc_N PF01056.18 KEG06874.1 - 0.048 13.6 1.5 0.048 13.5 1.5 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Cwf_Cwc_15 PF04889.12 KEG06874.1 - 0.11 12.3 5.4 0.1 12.3 5.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KEG06874.1 - 0.15 11.3 5.0 0.17 11.2 5.0 1.0 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KEG06874.1 - 0.16 12.4 4.7 0.2 12.1 4.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 KEG06874.1 - 0.19 11.9 5.7 0.25 11.6 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 KEG06874.1 - 1.5 9.3 9.5 1.7 9.1 9.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.32 KEG06875.1 - 7.9e-09 36.0 1.0 0.17 12.8 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 KEG06875.1 - 0.018 13.7 1.2 3.1 6.3 0.2 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Hira PF07569.11 KEG06875.1 - 0.11 12.2 0.3 2.5 7.8 0.0 2.9 2 1 1 3 3 3 0 TUP1-like enhancer of split NAD_binding_10 PF13460.6 KEG06880.1 - 0.068 13.1 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF5393 PF17371.2 KEG06882.1 - 0.078 11.1 0.0 0.078 11.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5393) PX PF00787.24 KEG06885.1 - 0.00088 19.2 0.0 0.00094 19.1 0.0 1.1 1 0 0 1 1 1 1 PX domain CAP_N PF01213.19 KEG06886.1 - 0.49 9.8 3.6 0.58 9.6 3.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1180 PF06679.12 KEG06886.1 - 0.61 10.5 4.4 0.83 10.0 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SRTM1 PF15872.5 KEG06887.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.5 1 1 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Hist_deacetyl PF00850.19 KEG06888.1 - 0.037 13.5 1.0 0.065 12.7 1.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain tRNA-synt_2 PF00152.20 KEG06890.1 - 4.3e-77 259.3 0.1 5.6e-77 258.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEG06890.1 - 3.5e-12 46.1 0.1 6.7e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEG06890.1 - 6.2e-07 29.1 0.0 0.0043 16.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Seryl_tRNA_N PF02403.22 KEG06890.1 - 0.0068 16.6 1.4 0.0068 16.6 1.4 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CP12 PF02672.15 KEG06890.1 - 0.032 15.0 0.6 0.065 14.0 0.6 1.5 1 0 0 1 1 1 0 CP12 domain M20_dimer PF07687.14 KEG06891.1 - 3.3e-18 65.6 0.0 4.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KEG06891.1 - 9.4e-11 41.8 0.1 1.6e-10 41.0 0.1 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Golgin_A5 PF09787.9 KEG06892.1 - 0.032 13.7 4.7 0.037 13.5 4.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-U1 PF06220.12 KEG06892.1 - 0.074 12.8 0.6 3.4 7.5 0.1 2.2 2 0 0 2 2 2 0 U1 zinc finger Nmad3 PF18754.1 KEG06892.1 - 0.12 11.9 1.8 0.15 11.6 1.8 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 XhlA PF10779.9 KEG06892.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA ANAPC_CDC26 PF10471.9 KEG06892.1 - 0.48 11.3 9.1 0.069 14.0 2.6 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DASH_Spc19 PF08287.11 KEG06892.1 - 6.9 6.5 11.0 0.17 11.8 2.4 1.9 1 1 1 2 2 2 0 Spc19 Shadoo PF14999.6 KEG06893.1 - 0.0053 16.9 0.8 0.014 15.5 0.8 1.6 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective APG6_N PF17675.1 KEG06893.1 - 0.01 16.4 8.6 0.01 16.4 8.6 6.8 4 1 2 6 6 6 0 Apg6 coiled-coil region GPHR_N PF12537.8 KEG06893.1 - 1.1 9.4 4.7 8.5 6.5 0.1 4.4 3 1 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal SUZ PF12752.7 KEG06893.1 - 6.3 7.6 13.1 0.57 11.0 5.2 3.4 2 0 0 2 2 2 0 SUZ domain CTD_bind PF04818.13 KEG06894.1 - 0.026 15.4 0.0 0.099 13.5 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF2267 PF10025.9 KEG06894.1 - 0.34 11.2 2.2 2.2 8.6 0.1 3.1 3 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Glyco_hydro_31 PF01055.26 KEG06895.1 - 2.1e-15 56.9 0.0 1.9e-14 53.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DrsE PF02635.15 KEG06895.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 DsrE/DsrF-like family MycE_N PF17843.1 KEG06896.1 - 0.14 12.6 1.1 1.8 9.1 0.1 2.3 2 0 0 2 2 2 0 MycE methyltransferase N-terminal Phytochelatin PF05023.14 KEG06899.1 - 2.1e-12 46.7 0.0 1.5e-05 24.4 0.0 4.2 5 0 0 5 5 5 3 Phytochelatin synthase Nucleoside_tran PF01733.18 KEG06901.1 - 1.7e-30 106.5 4.4 1.7e-30 106.5 4.4 1.6 2 0 0 2 2 2 1 Nucleoside transporter Collectrin PF16959.5 KEG06901.1 - 0.13 12.0 0.9 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Renal amino acid transporter PRD1_DD PF11087.8 KEG06902.1 - 0.13 12.0 0.5 0.2 11.4 0.5 1.3 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery OCRE PF17780.1 KEG06904.1 - 0.00025 21.0 1.0 0.00051 20.0 1.0 1.4 1 0 0 1 1 1 1 OCRE domain PMP22_Claudin PF00822.20 KEG06904.1 - 0.054 13.4 7.5 0.16 11.9 7.5 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1367 PF07105.11 KEG06906.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) MIOX PF05153.15 KEG06912.1 - 4e-05 23.3 0.7 0.14 11.7 0.1 2.3 2 0 0 2 2 2 2 Myo-inositol oxygenase B9-C2 PF07162.11 KEG06913.1 - 2.8e-16 60.2 0.0 4.4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein ETF_alpha PF00766.19 KEG06913.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Pet100 PF09803.9 KEG06915.1 - 0.045 14.3 7.6 0.8 10.3 7.6 2.2 1 1 0 1 1 1 0 Pet100 zf-RING_2 PF13639.6 KEG06916.1 - 1.1e-11 44.9 4.9 1.8e-11 44.2 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEG06916.1 - 2.4e-09 37.3 9.1 5.8e-09 36.1 9.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KEG06916.1 - 1.6e-07 31.0 7.8 4.7e-07 29.5 7.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG06916.1 - 3.6e-07 29.9 5.0 6.5e-07 29.1 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG06916.1 - 4.3e-05 23.5 3.5 6.8e-05 22.8 3.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KEG06916.1 - 0.00011 21.9 2.5 0.00011 21.9 2.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KEG06916.1 - 0.00055 19.8 7.1 0.00097 19.0 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG06916.1 - 0.00077 19.4 1.5 0.0021 18.0 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEG06916.1 - 0.0013 18.6 7.4 0.0023 17.7 5.9 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KEG06916.1 - 0.0045 17.1 6.5 0.019 15.1 6.5 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_6 PF14835.6 KEG06916.1 - 0.012 15.5 0.3 0.031 14.2 0.1 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Utp13 PF08625.11 KEG06916.1 - 0.028 14.3 0.0 1.9 8.4 0.0 2.6 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain Zn_ribbon_17 PF17120.5 KEG06916.1 - 0.041 13.5 7.6 0.099 12.3 7.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KEG06916.1 - 0.056 13.3 6.6 0.051 13.4 5.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KEG06916.1 - 0.097 13.0 5.5 0.21 11.9 5.5 1.5 1 0 0 1 1 1 0 RING-like domain Papo_T_antigen PF02380.15 KEG06916.1 - 0.12 12.5 2.7 0.19 11.9 2.7 1.2 1 0 0 1 1 1 0 T-antigen specific domain zf-Nse PF11789.8 KEG06916.1 - 0.15 11.9 1.9 0.32 10.9 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KEG06916.1 - 0.22 11.3 6.2 0.32 10.8 5.0 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KEG06916.1 - 0.34 11.1 4.6 0.73 10.0 4.6 1.6 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 KEG06916.1 - 0.37 10.7 8.6 0.86 9.6 8.6 1.7 1 1 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KEG06916.1 - 1.4 9.0 6.6 4.7 7.4 6.6 1.9 1 1 0 1 1 1 0 PHD-finger C_Hendra PF16821.5 KEG06919.1 - 0.27 11.1 5.4 0.12 12.3 2.4 1.8 2 0 0 2 2 2 0 C protein from hendra and measles viruses Leu_zip PF15294.6 KEG06919.1 - 1.2 8.5 19.7 0.074 12.5 5.7 2.1 1 1 1 2 2 2 0 Leucine zipper Na_trans_assoc PF06512.13 KEG06919.1 - 1.7 8.8 10.3 2.5 8.3 10.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Golgin_A5 PF09787.9 KEG06919.1 - 1.8 7.9 14.0 2.4 7.5 14.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 EphA2_TM PF14575.6 KEG06921.1 - 0.03 15.2 0.0 0.048 14.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KEG06921.1 - 0.037 14.3 0.1 0.065 13.5 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RBB1NT PF08169.11 KEG06921.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Amnionless PF14828.6 KEG06921.1 - 0.091 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless TrbL PF04610.14 KEG06921.1 - 0.11 12.2 0.4 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Rab_bind PF16704.5 KEG06921.1 - 0.12 12.4 0.1 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Rab binding domain CD34_antigen PF06365.12 KEG06921.1 - 0.24 11.0 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4690 PF15756.5 KEG06921.1 - 0.29 11.8 0.1 0.29 11.8 0.1 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage LRR_4 PF12799.7 KEG06925.1 - 0.0002 21.7 4.7 0.087 13.3 0.0 5.0 4 3 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG06925.1 - 0.00031 20.5 0.4 0.036 13.8 0.0 3.6 4 1 1 5 5 5 1 Leucine rich repeat LRRNT_2 PF08263.12 KEG06925.1 - 0.0041 17.4 2.2 0.0087 16.4 0.1 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KEG06925.1 - 0.0043 17.4 0.9 2.8 8.8 0.0 3.5 4 0 0 4 4 4 1 Leucine Rich Repeat Nucleoside_tran PF01733.18 KEG06925.1 - 0.053 12.9 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter LRR_4 PF12799.7 KEG06927.1 - 0.00095 19.5 0.0 0.14 12.6 0.0 2.9 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG06927.1 - 0.011 15.4 0.0 6.4 6.6 0.0 3.0 2 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 KEG06927.1 - 0.022 15.3 0.0 47 5.1 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KEG06927.1 - 0.028 14.5 0.1 10 6.5 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat zf-C2HC_2 PF13913.6 KEG06930.1 - 1.7e-07 30.9 0.2 2.7e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type PQQ_3 PF13570.6 KEG06931.1 - 0.012 16.0 0.6 0.85 10.2 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain Albumin_I PF08027.11 KEG06931.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Albumin I chain b WD40 PF00400.32 KEG06931.1 - 0.054 14.4 0.2 31 5.6 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Methyltransf_23 PF13489.6 KEG06932.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG06932.1 - 0.00027 21.6 0.0 0.13 13.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEG06932.1 - 0.00066 20.3 0.0 0.33 11.6 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG06932.1 - 0.00091 19.9 0.1 0.021 15.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG06932.1 - 0.034 13.9 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KEG06932.1 - 0.19 11.0 0.0 0.43 9.8 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TatD_DNase PF01026.21 KEG06934.1 - 2e-23 83.1 0.0 4.7e-23 81.9 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase TPR_2 PF07719.17 KEG06935.1 - 4.2e-08 32.7 5.1 0.0025 17.8 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG06935.1 - 1.7e-06 27.7 3.7 0.0065 16.4 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG06935.1 - 0.00036 20.2 2.4 0.25 11.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG06935.1 - 0.00056 19.9 0.4 0.16 12.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG06935.1 - 0.00085 19.8 1.0 0.0055 17.2 0.4 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG06935.1 - 0.0029 17.9 11.8 0.083 13.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG06935.1 - 0.038 14.6 2.1 0.038 14.6 2.1 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG06935.1 - 0.045 14.6 6.9 2.9 8.9 0.0 4.2 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG06935.1 - 0.12 13.0 0.2 2.9 8.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SAPS PF04499.15 KEG06935.1 - 1.2 7.8 4.0 1.7 7.3 4.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPL5 PF18168.1 KEG06935.1 - 3 7.0 7.1 5.4 6.2 7.1 1.3 1 0 0 1 1 1 0 Prim-pol family 5 CENP-B_dimeris PF09026.10 KEG06935.1 - 3.7 8.0 23.1 0.056 13.8 14.7 2.1 1 1 1 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KEG06935.1 - 7.9 5.7 15.3 14 4.9 15.3 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KEG06935.1 - 9.8 4.2 18.2 14 3.7 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family Peripla_BP_6 PF13458.6 KEG06936.1 - 4e-11 43.2 0.0 1.7e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG06936.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain cNMP_binding PF00027.29 KEG06938.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain RHSP PF07999.11 KEG06939.1 - 6.1e-20 71.5 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein RHSP PF07999.11 KEG06940.1 - 3.7e-31 108.4 0.2 4.2e-31 108.2 0.2 1.0 1 0 0 1 1 1 1 Retrotransposon hot spot protein ATPase PF06745.13 KEG06940.1 - 0.081 12.3 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KEG06940.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1214 PF06742.11 KEG06948.1 - 0.075 13.5 0.2 0.3 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1214) Methyltransf_11 PF08241.12 KEG06950.1 - 4.1e-11 43.4 0.0 4.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KEG06950.1 - 1.2e-10 42.0 0.0 6.2e-06 26.8 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain WBS_methylT PF12589.8 KEG06950.1 - 6.6e-08 33.2 5.4 2.1e-07 31.6 5.4 1.9 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_23 PF13489.6 KEG06950.1 - 1.4e-07 31.5 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG06950.1 - 2.4e-06 28.2 0.0 2.9e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG06950.1 - 0.00018 21.3 0.0 0.004 17.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KEG06950.1 - 0.01 15.1 0.0 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KEG06950.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Retinal PF15449.6 KEG06950.1 - 4.4 4.9 7.6 0.27 9.0 0.7 1.9 2 0 0 2 2 2 0 Retinal protein SPT6_acidic PF14632.6 KEG06950.1 - 5.6 7.6 24.0 3.3 8.3 5.5 2.8 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Mucin PF01456.17 KEG06952.1 - 0.0019 18.2 24.5 0.028 14.4 8.1 3.0 2 2 0 2 2 2 2 Mucin-like glycoprotein Pro_CA PF00484.19 KEG06952.1 - 0.15 12.4 0.3 0.15 12.4 0.3 3.1 2 1 2 4 4 4 0 Carbonic anhydrase FXR_C3 PF16097.5 KEG06952.1 - 0.39 11.4 0.1 0.39 11.4 0.1 3.3 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 3 Filament PF00038.21 KEG06952.1 - 5.1 6.6 10.7 0.1 12.2 1.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF4685 PF15737.5 KEG06954.1 - 0.0052 17.2 0.7 0.16 12.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4685) ACC_epsilon PF13822.6 KEG06954.1 - 0.027 15.1 1.3 0.071 13.8 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit JHY PF15261.6 KEG06955.1 - 1.6e-15 58.0 9.1 2.4e-15 57.4 7.3 2.3 2 1 0 2 2 2 1 Jhy protein DUF4186 PF13811.6 KEG06955.1 - 0.19 11.8 0.4 0.38 10.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) PhoU PF01895.19 KEG06956.1 - 0.12 12.9 0.1 0.17 12.4 0.1 1.2 1 0 0 1 1 1 0 PhoU domain Ribosomal_60s PF00428.19 KEG06957.1 - 0.0014 19.1 4.8 0.0014 19.1 4.8 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein EPF PF17181.4 KEG06957.1 - 0.014 15.4 1.8 0.032 14.2 1.8 1.7 1 0 0 1 1 1 0 Epidermal patterning factor proteins DarA_C PF18789.1 KEG06957.1 - 0.06 13.7 0.3 2 8.8 0.0 2.1 2 0 0 2 2 2 0 Defence against restriction A C-terminal FYVE PF01363.21 KEG06958.1 - 2.8e-20 72.2 4.0 2.8e-20 72.2 4.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger Ank_2 PF12796.7 KEG06961.1 - 9.6e-26 90.2 3.3 9.6e-12 45.3 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG06961.1 - 7.1e-19 67.6 15.7 6.2e-08 32.8 0.4 6.6 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG06961.1 - 9.4e-18 62.5 10.8 0.002 18.4 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KEG06961.1 - 9.2e-16 58.0 8.4 5.1e-08 33.3 0.1 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KEG06961.1 - 2.4e-12 46.7 18.8 0.00077 19.8 0.3 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 KEG06962.1 - 3.7e-22 78.7 0.9 3.4e-08 34.0 0.0 4.5 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEG06962.1 - 4.3e-15 54.3 3.9 0.024 15.2 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KEG06962.1 - 5.9e-15 55.0 8.2 0.00021 21.6 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KEG06962.1 - 7.7e-12 45.2 4.6 0.00037 20.7 0.2 5.3 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEG06962.1 - 9.8e-12 45.2 1.2 0.0015 19.1 0.1 5.0 4 2 1 5 5 5 2 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 KEG06965.1 - 0.021 14.4 0.3 0.44 10.2 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 KEG06965.1 - 0.068 13.1 0.0 0.94 9.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KEG06965.1 - 0.07 13.6 0.1 0.27 11.7 0.0 2.0 2 1 0 2 2 2 0 EF-hand domain pair IPK PF03770.16 KEG06967.1 - 2.6e-17 63.3 0.0 3.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase L27_1 PF09058.10 KEG06967.1 - 0.1 12.6 0.0 0.39 10.7 0.0 2.0 3 0 0 3 3 3 0 L27_1 zf-C2H2_4 PF13894.6 KEG06970.1 - 2.5e-09 37.1 32.3 0.063 14.1 0.4 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.12 KEG06970.1 - 2.7e-07 30.8 14.6 0.046 14.0 0.1 4.9 5 0 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KEG06970.1 - 7e-07 29.4 20.9 0.055 14.0 0.2 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KEG06970.1 - 4.6e-05 23.0 9.8 2.9 7.6 0.5 5.2 5 0 0 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KEG06970.1 - 0.019 15.3 9.2 7.9 7.0 0.0 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KEG06970.1 - 0.027 14.3 1.6 5.6 6.9 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KEG06970.1 - 0.029 14.7 12.7 9.6 6.6 0.3 4.9 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 KEG06970.1 - 0.031 14.0 0.1 0.031 14.0 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KEG06970.1 - 0.11 13.0 32.5 3.7 8.2 3.0 7.8 8 1 0 8 8 7 0 Zinc-finger double domain zf-MYST PF17772.1 KEG06970.1 - 0.14 11.8 5.2 2 8.1 0.2 3.4 4 0 0 4 4 4 0 MYST family zinc finger domain zf-C2H2_12 PF18658.1 KEG06970.1 - 0.2 11.3 6.1 2.4 7.8 0.7 3.5 4 0 0 4 4 4 0 Zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KEG06970.1 - 0.24 11.7 8.9 4.2 7.8 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 KEG06970.1 - 0.58 9.3 5.2 11 5.1 0.0 3.7 2 2 0 2 2 2 0 Putative actin-like family zf-BED PF02892.15 KEG06970.1 - 0.72 9.9 17.9 0.85 9.7 0.0 5.0 5 1 0 5 5 5 0 BED zinc finger UPF0547 PF10571.9 KEG06970.1 - 1 9.5 0.0 1 9.5 0.0 3.4 4 0 0 4 4 2 0 Uncharacterised protein family UPF0547 CpXC PF14353.6 KEG06970.1 - 1.6 8.8 6.4 13 5.8 0.5 3.3 2 1 1 3 3 3 0 CpXC protein Exo_endo_phos_2 PF14529.6 KEG06971.1 - 9e-09 35.2 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ZZ PF00569.17 KEG06976.1 - 0.0057 16.4 1.5 0.015 15.1 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type FYVE PF01363.21 KEG06976.1 - 0.017 15.2 0.7 0.034 14.3 0.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger Aa_trans PF01490.18 KEG06977.1 - 6.9e-53 179.8 33.8 9e-53 179.4 33.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG06977.1 - 8.7e-12 44.8 13.0 8.7e-12 44.8 13.0 2.0 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 KEG06977.1 - 0.00038 19.4 24.1 0.00038 19.4 24.1 2.1 1 1 1 2 2 2 1 Amino acid permease PP2 PF14299.6 KEG06977.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 Phloem protein 2 OGFr_N PF04664.13 KEG06984.1 - 2.1e-11 43.8 0.6 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region HSP70 PF00012.20 KEG06985.1 - 5.2e-79 266.0 0.1 1.2e-78 264.8 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KEG06985.1 - 3.1e-05 23.0 0.1 0.0024 16.8 0.1 2.8 2 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KEG06985.1 - 0.052 12.5 0.0 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain GCN5L1 PF06320.13 KEG06985.1 - 0.067 13.3 1.4 1.7 8.8 0.8 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FtsA PF14450.6 KEG06985.1 - 0.16 12.4 0.0 4.8 7.7 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA TFIIA PF03153.13 KEG06986.1 - 0.021 14.8 32.7 0.039 14.0 32.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spem1 PF15670.5 KEG06986.1 - 0.094 12.3 18.3 0.012 15.2 14.2 1.5 2 0 0 2 2 2 0 Spermatid maturation protein 1 PPL5 PF18168.1 KEG06987.1 - 3.3e-104 348.6 7.5 4e-93 312.2 0.8 3.7 2 1 1 3 3 3 2 Prim-pol family 5 PriCT_2 PF08707.11 KEG06987.1 - 1.6e-13 50.8 0.2 3.6e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) MAP17 PF15807.5 KEG06988.1 - 0.011 15.9 0.6 0.075 13.3 0.2 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EphA2_TM PF14575.6 KEG06988.1 - 0.18 12.7 0.7 2.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 KEG06989.1 - 0.055 13.7 4.5 0.21 11.8 0.7 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Methyltransf_3 PF01596.17 KEG06989.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase EphA2_TM PF14575.6 KEG06989.1 - 0.095 13.6 0.5 20 6.1 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3836 PF12930.7 KEG06989.1 - 0.25 11.1 1.6 8.4 6.2 1.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF3836) MAP17 PF15807.5 KEG06990.1 - 0.0071 16.6 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Rab5ip PF07019.12 KEG06990.1 - 0.046 14.3 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Transket_pyr PF02779.24 KEG06995.1 - 3.8e-59 199.3 0.0 5.8e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KEG06995.1 - 1.1e-50 172.3 0.0 1.9e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KEG06995.1 - 2.6e-42 144.1 0.0 4.3e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KEG06995.1 - 3.9e-12 45.6 1.0 8.6e-12 44.5 1.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus NIPSNAP PF07978.13 KEG06996.1 - 3.7e-17 62.4 0.1 8.8e-16 58.0 0.2 2.1 2 0 0 2 2 2 1 NIPSNAP Peripla_BP_6 PF13458.6 KEG06998.1 - 5.5e-12 46.0 2.2 1.1e-09 38.4 1.2 2.6 3 0 0 3 3 3 2 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG06998.1 - 2.4e-07 30.5 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AJAP1_PANP_C PF15298.6 KEG06998.1 - 0.023 14.9 0.2 0.071 13.3 0.2 1.9 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Adeno_E3_CR2 PF02439.15 KEG06998.1 - 0.07 12.9 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Guanylate_cyc PF00211.20 KEG06999.1 - 3.8e-21 75.5 0.0 4.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Hairy_orange PF07527.13 KEG07000.1 - 0.028 14.6 0.1 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Hairy Orange IQ PF00612.27 KEG07001.1 - 9.5 6.3 9.5 25 5.0 0.7 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4887 PF16228.5 KEG07003.1 - 0.17 12.0 5.8 0.12 12.6 4.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) ECH_1 PF00378.20 KEG07004.1 - 8.7e-40 136.6 0.0 1.3e-33 116.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEG07004.1 - 1.8e-16 60.6 0.1 2.8e-15 56.7 0.0 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 KEG07004.1 - 0.054 12.1 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain Flavi_glycop_C PF02832.16 KEG07004.1 - 0.18 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain RRM_1 PF00076.22 KEG07005.1 - 1.3e-15 57.0 0.0 3.5e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG07005.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Peripla_BP_6 PF13458.6 KEG07006.1 - 8.9e-08 32.2 2.5 0.003 17.3 0.0 2.6 2 1 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG07006.1 - 0.054 13.1 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DUF1380 PF07128.12 KEG07008.1 - 0.085 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Colicin_Pyocin PF01320.18 KEG07008.1 - 0.17 12.0 0.2 0.37 10.9 0.1 1.5 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein COG4 PF08318.12 KEG07009.1 - 2e-28 99.5 0.0 2.2e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 COG4 transport protein COG4 PF08318.12 KEG07010.1 - 3.4e-11 42.8 0.0 1.1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 KEG07010.1 - 0.00069 18.6 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ABC_tran_CTD PF16326.5 KEG07010.1 - 0.032 14.5 0.3 0.078 13.2 0.3 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Surp PF01805.20 KEG07011.1 - 1.1e-12 47.7 0.1 1.1e-12 47.7 0.1 1.8 2 0 0 2 2 2 1 Surp module Peptidase_M8 PF01457.16 KEG07012.1 - 1.9e-136 455.8 0.0 2.4e-136 455.5 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin CD34_antigen PF06365.12 KEG07013.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 KEG07013.1 - 0.029 15.3 0.0 0.055 14.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 KEG07013.1 - 1.9 9.1 6.5 0.18 12.4 0.5 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage PARP PF00644.20 KEG07014.1 - 2e-61 207.0 0.0 4.4e-61 205.9 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KEG07014.1 - 8.1e-40 136.1 0.0 1.5e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KEG07014.1 - 6.8e-28 96.6 1.2 1.5e-27 95.5 1.2 1.6 1 0 0 1 1 1 1 WGR domain PA28_alpha PF02251.18 KEG07014.1 - 0.21 11.6 0.7 0.39 10.8 0.2 1.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Myosin_TH1 PF06017.13 KEG07015.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding DUF1478 PF07349.11 KEG07015.1 - 0.023 14.6 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) BBS1 PF14779.6 KEG07015.1 - 0.12 11.7 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 TSC22 PF01166.18 KEG07015.1 - 0.2 12.0 0.2 0.2 12.0 0.2 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family ACC_epsilon PF13822.6 KEG07015.1 - 0.73 10.6 6.3 0.23 12.2 1.3 2.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit PRKG1_interact PF15898.5 KEG07015.1 - 1 10.3 5.8 2.4 9.1 5.8 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 KEG07015.1 - 7.1 6.5 9.3 0.48 10.2 0.9 2.8 2 1 1 3 3 3 0 Septum formation initiator MIX PF18529.1 KEG07016.1 - 1.1e-93 310.9 1.1 1.2e-93 310.7 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial membrane-anchored proteins Tudor_3 PF18115.1 KEG07016.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain LRR_4 PF12799.7 KEG07017.1 - 1e-27 95.7 10.9 2.6e-05 24.5 0.0 11.5 6 4 5 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG07017.1 - 2.2e-11 43.3 18.7 0.33 10.8 0.1 8.6 5 3 1 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 KEG07017.1 - 8.3e-08 31.7 24.4 0.67 10.2 0.0 11.8 13 0 0 13 13 13 4 Leucine Rich repeat LRR_9 PF14580.6 KEG07017.1 - 0.28 10.7 8.0 8.5 5.8 0.0 5.1 3 2 4 7 7 7 0 Leucine-rich repeat OmpH PF03938.14 KEG07022.1 - 0.015 15.6 4.7 0.015 15.6 4.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) APC_u15 PF16636.5 KEG07022.1 - 3 8.3 5.7 43 4.6 2.8 3.0 2 1 1 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 Galactosyl_T PF01762.21 KEG07023.1 - 0.012 15.4 0.0 2 8.2 0.0 3.1 3 1 0 3 3 3 0 Galactosyltransferase Galactosyl_T PF01762.21 KEG07024.1 - 0.00069 19.5 0.0 0.26 11.1 0.0 3.2 3 1 0 3 3 3 1 Galactosyltransferase DUF2417 PF10329.9 KEG07024.1 - 0.0042 16.5 0.3 0.0061 16.0 0.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) YbhQ PF11076.8 KEG07024.1 - 0.069 13.2 1.1 0.58 10.2 0.5 2.2 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Dpy-30 PF05186.13 KEG07026.1 - 9.8e-16 57.2 0.0 1.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KEG07026.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit SOTI PF17079.5 KEG07026.1 - 0.077 13.4 0.0 0.093 13.1 0.0 1.2 1 0 0 1 1 1 0 Male-specific protein scotti zf-CDGSH PF09360.10 KEG07028.1 - 1.4e-18 66.8 4.5 4.2e-10 39.7 0.4 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Bystin PF05291.11 KEG07030.1 - 7.2e-111 370.1 0.2 9.4e-111 369.8 0.2 1.1 1 0 0 1 1 1 1 Bystin DUF3299 PF11736.8 KEG07030.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) ATP-synt_E_2 PF08112.11 KEG07031.1 - 0.039 14.2 3.8 0.99 9.7 0.7 3.0 3 0 0 3 3 3 0 ATP synthase epsilon subunit Fzo_mitofusin PF04799.13 KEG07031.1 - 4.5 6.8 7.8 0.99 8.9 3.4 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF3552 PF12072.8 KEG07031.1 - 6.3 6.2 37.9 0.91 8.9 19.7 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) DUF2624 PF11116.8 KEG07032.1 - 0.017 16.0 0.0 0.026 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Pox_Ag35 PF03286.14 KEG07032.1 - 0.23 11.2 5.4 0.32 10.7 5.4 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein PUF PF00806.19 KEG07034.1 - 2.5e-24 83.5 0.4 4.4e-05 22.9 0.0 5.5 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat TFIIA PF03153.13 KEG07034.1 - 2.4 8.0 28.4 1.5 8.7 11.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BILBO1_N PF18281.1 KEG07036.1 - 5e-37 126.2 0.0 7e-37 125.8 0.0 1.2 1 0 0 1 1 1 1 BILBO1 N-terminal domain SIP1 PF04938.12 KEG07037.1 - 6.1e-05 22.8 0.1 0.00011 22.0 0.1 1.8 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Glycolytic PF00274.19 KEG07039.1 - 2.2e-145 483.8 0.0 2.4e-145 483.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Lipid_DES PF08557.10 KEG07041.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.8 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Nodulin-like PF06813.13 KEG07042.1 - 2.7e-11 43.4 10.4 2.7e-11 43.4 10.4 2.4 2 1 0 2 2 2 1 Nodulin-like DUF1129 PF06570.11 KEG07042.1 - 0.05 13.1 5.5 0.34 10.4 3.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Saf_2TM PF18303.1 KEG07042.1 - 0.091 12.4 7.5 6.8 6.3 0.1 4.1 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain CoA_trans PF01144.23 KEG07043.1 - 3.2e-72 242.4 0.1 4.8e-52 176.5 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KEG07043.1 - 0.026 12.9 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter SNase PF00565.17 KEG07046.1 - 4.3e-05 23.9 0.0 6.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Peptidase_M8 PF01457.16 KEG07047.1 - 2.1e-105 353.4 6.7 2.8e-59 201.2 4.1 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG07047.1 - 0.0026 18.0 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 KAR PF15222.6 KEG07047.1 - 0.12 12.7 1.3 0.5 10.7 0.0 2.4 2 1 1 3 3 3 0 Kidney androgen-regulated zf-CCHC PF00098.23 KEG07049.1 - 0.0059 16.6 3.0 0.012 15.7 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Taxilin PF09728.9 KEG07049.1 - 0.008 15.4 1.1 0.011 14.9 1.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Myosin_tail_1 PF01576.19 KEG07049.1 - 0.0083 14.0 1.4 0.013 13.4 1.4 1.2 1 0 0 1 1 1 1 Myosin tail zf-CCHC_2 PF13696.6 KEG07049.1 - 0.075 12.9 1.3 0.15 11.9 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RsbU_N PF08673.10 KEG07049.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF3450 PF11932.8 KEG07049.1 - 0.66 9.2 7.7 1.3 8.3 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 KEG07049.1 - 1 9.1 4.6 2.1 8.2 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spt20 PF12090.8 KEG07052.1 - 0.31 10.6 18.7 0.46 10.0 18.7 1.2 1 0 0 1 1 1 0 Spt20 family Metallophos PF00149.28 KEG07053.1 - 2.9e-30 106.3 0.0 4.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RVT_1 PF00078.27 KEG07058.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Endonuclease_NS PF01223.23 KEG07059.1 - 4.3e-27 95.4 0.0 7.2e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Peptidase_M1 PF01433.20 KEG07060.1 - 2.5e-81 272.4 1.1 4.6e-81 271.5 1.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KEG07060.1 - 1.6e-55 188.9 1.2 1.6e-55 188.9 1.2 2.3 4 0 0 4 4 4 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KEG07060.1 - 3e-48 164.5 0.0 6e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ELMO_CED12 PF04727.13 KEG07061.1 - 1e-21 77.8 0.0 1.5e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family ELMO_CED12 PF04727.13 KEG07062.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 ELMO/CED-12 family Pkinase PF00069.25 KEG07063.1 - 1.8e-46 158.7 0.0 4.5e-46 157.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07063.1 - 7.6e-30 104.1 0.0 1.4e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG07063.1 - 0.00011 22.7 0.1 0.00027 21.4 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KEG07063.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG07063.1 - 0.0014 17.4 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PH_9 PF15410.6 KEG07063.1 - 0.0093 16.3 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain HCO3_cotransp PF00955.21 KEG07063.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family PH_6 PF15406.6 KEG07063.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain YL1 PF05764.13 KEG07066.1 - 1.1e-12 48.6 14.0 1.4e-12 48.3 14.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Kelch_1 PF01344.25 KEG07067.1 - 1.2e-11 44.0 0.4 0.00018 21.0 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 KEG07067.1 - 3.1e-09 36.6 0.8 8.9e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KEG07067.1 - 6.4e-08 32.6 0.2 0.00074 19.7 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 KEG07067.1 - 3.9e-07 29.8 0.3 0.13 12.3 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KEG07067.1 - 4.4e-07 29.8 9.4 0.0023 17.9 0.2 4.5 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KEG07067.1 - 0.00017 21.8 15.5 0.17 12.3 0.2 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain SQS_PSY PF00494.19 KEG07073.1 - 8.3e-41 140.2 1.5 8.3e-41 140.2 1.5 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase AA_synth PF06684.11 KEG07075.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Amino acid synthesis Sec8_exocyst PF04048.14 KEG07077.1 - 1.2e-09 38.2 0.0 3.4e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KEG07077.1 - 0.014 14.7 0.3 0.026 13.8 0.3 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex SDA1 PF05285.12 KEG07077.1 - 0.13 11.7 26.8 0.24 10.8 25.4 2.0 2 0 0 2 2 2 0 SDA1 SAPS PF04499.15 KEG07077.1 - 0.96 8.2 7.0 1 8.1 4.6 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.13 KEG07077.1 - 1.3 9.3 12.0 4.4 7.5 12.0 1.9 1 0 0 1 1 1 0 Sodium ion transport-associated AAA_23 PF13476.6 KEG07077.1 - 1.5 9.3 7.4 9.1 6.7 7.6 2.1 2 0 0 2 2 2 0 AAA domain DUF2099 PF09872.9 KEG07078.1 - 0.18 11.0 0.1 0.39 9.9 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) Lipase_GDSL_2 PF13472.6 KEG07079.1 - 2e-08 34.8 0.0 0.00051 20.5 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEG07079.1 - 5.9e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AKAP7_NLS PF10469.9 KEG07081.1 - 1.1e-25 90.8 0.0 3.9e-25 89.0 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KEG07081.1 - 2e-06 27.8 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MalF_P2 PF14785.6 KEG07081.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain OCC1 PF15506.6 KEG07083.1 - 2.7 8.2 7.2 0.39 10.9 2.3 2.1 2 0 0 2 2 2 0 OCC1 family PRIMA1 PF16101.5 KEG07084.1 - 0.06 13.4 8.9 0.13 12.3 8.8 1.6 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 EB1 PF03271.17 KEG07085.1 - 1.2e-09 38.2 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 EB1-like C-terminal motif DUF630 PF04783.12 KEG07086.1 - 0.13 12.5 4.3 0.44 10.7 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF630) GAT PF03127.14 KEG07086.1 - 6.5 7.1 6.8 2.8 8.3 0.2 3.6 5 0 0 5 5 5 0 GAT domain Ribosomal_L37ae PF01780.19 KEG07087.1 - 3.9e-36 123.0 4.1 4.4e-36 122.8 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 KEG07087.1 - 0.0026 17.6 2.0 0.0037 17.1 2.0 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 KEG07087.1 - 0.047 13.8 1.0 0.063 13.4 1.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KEG07087.1 - 0.062 13.3 2.6 0.1 12.6 2.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 KEG07087.1 - 0.18 12.0 3.3 0.6 10.3 0.4 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-HIT PF04438.16 KEG07087.1 - 0.22 11.4 2.4 0.31 11.0 0.5 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_2 PF13923.6 KEG07088.1 - 1.7e-10 40.6 6.6 3.1e-10 39.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG07088.1 - 4.5e-10 39.2 4.1 6.9e-10 38.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG07088.1 - 6.9e-10 38.6 5.3 1.1e-09 37.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG07088.1 - 1.2e-09 38.4 8.1 1.9e-09 37.7 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEG07088.1 - 3.6e-09 36.5 2.9 6.5e-09 35.7 1.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KEG07088.1 - 1e-08 35.2 7.3 2e-08 34.2 7.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEG07088.1 - 2.1e-08 33.9 3.6 3.7e-08 33.1 3.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEG07088.1 - 3.9e-08 33.1 4.2 6.8e-08 32.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KEG07088.1 - 0.00011 22.2 1.3 0.00022 21.2 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KEG07088.1 - 0.00011 22.4 6.8 0.00011 22.4 6.8 2.5 3 1 0 3 3 2 1 RING-H2 zinc finger domain DUF4834 PF16118.5 KEG07088.1 - 0.016 16.2 0.1 5.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 KEG07088.1 - 0.023 15.0 3.7 0.93 9.8 0.2 2.9 1 1 1 2 2 2 0 Orf78 (ac78) Zn_ribbon_17 PF17120.5 KEG07088.1 - 0.1 12.3 5.0 0.21 11.2 5.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Anoctamin PF04547.12 KEG07088.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel zf-RING_10 PF16685.5 KEG07088.1 - 0.12 12.5 4.2 0.23 11.6 4.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KEG07088.1 - 0.14 12.0 6.5 0.52 10.1 6.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Suf PF05843.14 KEG07088.1 - 0.14 12.1 0.9 13 5.7 0.0 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2076 PF09849.9 KEG07088.1 - 0.2 11.7 12.7 0.12 12.4 1.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) RINGv PF12906.7 KEG07088.1 - 0.32 11.2 4.9 1.2 9.3 4.9 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 KEG07088.1 - 0.53 10.2 4.3 1.5 8.8 4.2 1.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein IBR PF01485.21 KEG07088.1 - 0.65 10.3 7.1 0.71 10.1 5.3 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain CDK2AP PF09806.9 KEG07088.1 - 0.95 9.5 6.7 0.81 9.7 1.3 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Pex14_N PF04695.13 KEG07088.1 - 1 10.0 15.3 7.1e+02 0.8 15.3 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region K_channel_TID PF07941.11 KEG07088.1 - 1.4 9.4 10.3 6 7.4 2.9 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4660 PF15559.6 KEG07088.1 - 2.3 8.6 6.2 1.5 9.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) FAD_binding_2 PF00890.24 KEG07090.1 - 4.5e-86 289.5 0.3 6.7e-86 289.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 KEG07090.1 - 6.2e-47 160.3 0.0 1.1e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 ApbE family Pyr_redox_2 PF07992.14 KEG07090.1 - 5.2e-09 35.7 0.1 1.3e-08 34.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEG07090.1 - 2.2e-07 30.8 6.4 5.4e-07 29.5 4.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KEG07090.1 - 2.5e-07 30.1 4.1 5.6e-06 25.7 1.8 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEG07090.1 - 5.8e-07 29.2 6.6 5.8e-07 29.2 6.6 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_1 PF00175.21 KEG07090.1 - 1.6e-06 28.7 0.0 6.5e-06 26.8 0.0 2.1 2 0 0 2 2 1 1 Oxidoreductase NAD-binding domain AlaDh_PNT_C PF01262.21 KEG07090.1 - 6.4e-06 25.6 0.2 1.4e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEG07090.1 - 1.8e-05 23.6 5.2 0.00075 18.3 3.2 2.5 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 KEG07090.1 - 2e-05 24.8 0.4 2e-05 24.8 0.4 3.6 4 0 0 4 4 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEG07090.1 - 0.0042 16.4 0.6 0.37 10.0 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEG07090.1 - 0.012 14.8 0.7 0.023 13.9 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KEG07090.1 - 0.03 14.9 3.2 0.037 14.6 0.7 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEG07090.1 - 0.48 9.4 1.9 2.7 6.9 1.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein SepSecS PF05889.13 KEG07091.1 - 5.1e-44 150.5 0.0 1e-43 149.5 0.0 1.4 1 1 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS FbpA PF05833.11 KEG07092.1 - 3.6e-34 118.3 3.1 3.6e-34 118.3 3.1 2.6 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KEG07092.1 - 2.3e-23 82.9 0.0 7e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KEG07092.1 - 3.9e-12 46.0 0.0 3.9e-12 46.0 0.0 3.7 3 1 0 3 3 3 1 NFACT protein C-terminal domain SUIM_assoc PF16619.5 KEG07092.1 - 0.019 15.0 0.5 0.019 15.0 0.5 6.2 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 TED_complement PF07678.14 KEG07092.1 - 0.057 12.4 0.7 0.21 10.5 0.8 1.8 2 0 0 2 2 2 0 A-macroglobulin TED domain PWWP PF00855.17 KEG07093.1 - 3.6e-09 36.9 0.1 6.1e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 PWWP domain GTP_EFTU PF00009.27 KEG07095.1 - 7.6e-20 71.3 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEG07095.1 - 2.7e-06 27.7 1.8 3.7e-06 27.2 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KEG07095.1 - 0.00034 20.9 0.5 0.0012 19.1 0.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KEG07095.1 - 0.0025 17.9 0.0 0.0079 16.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Eapp_C PF10238.9 KEG07096.1 - 7.2 6.7 18.1 0.26 11.4 4.3 2.8 2 1 0 2 2 2 0 E2F-associated phosphoprotein DND1_DSRM PF14709.7 KEG07097.1 - 0.0077 16.5 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 FAM199X PF15814.5 KEG07097.1 - 0.046 12.8 0.6 0.065 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X dsrm PF00035.26 KEG07097.1 - 0.17 12.6 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Mucin PF01456.17 KEG07099.1 - 3.6e-07 30.3 4.6 4.7e-07 29.9 4.6 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF5486 PF17588.2 KEG07100.1 - 0.021 14.7 0.1 0.067 13.1 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Lyx_isomer PF07385.12 KEG07100.1 - 0.043 13.1 0.4 0.084 12.1 0.2 1.6 2 0 0 2 2 2 0 D-lyxose isomerase DUF627 PF04781.12 KEG07100.1 - 0.3 11.1 4.9 0.12 12.4 1.1 2.2 2 1 0 3 3 3 0 Protein of unknown function (DUF627) Mucin PF01456.17 KEG07101.1 - 0.071 13.1 0.4 0.071 13.1 0.4 3.6 3 1 0 3 3 3 0 Mucin-like glycoprotein Mcm10 PF09332.11 KEG07101.1 - 3.5 7.0 18.4 0.64 9.4 9.8 2.2 2 0 0 2 2 2 0 Mcm10 replication factor Phage_GP20 PF06810.11 KEG07104.1 - 0.00047 20.0 6.4 4.7 7.0 1.0 4.4 4 0 0 4 4 4 2 Phage minor structural protein GP20 Fez1 PF06818.15 KEG07104.1 - 0.002 18.6 14.3 0.002 18.6 14.3 3.7 2 1 1 4 4 4 1 Fez1 COG5 PF10392.9 KEG07104.1 - 0.0024 18.0 5.8 0.72 10.0 1.4 3.2 2 0 0 2 2 2 2 Golgi transport complex subunit 5 TolA_bind_tri PF16331.5 KEG07104.1 - 0.11 12.6 35.5 2 8.6 0.5 6.7 4 2 2 6 6 6 0 TolA binding protein trimerisation FH2 PF02181.23 KEG07104.1 - 0.22 10.6 10.5 0.047 12.8 2.9 2.8 3 1 0 3 3 3 0 Formin Homology 2 Domain Vps54_N PF10475.9 KEG07104.1 - 0.23 10.7 5.2 5.2 6.3 0.5 2.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex IFT57 PF10498.9 KEG07104.1 - 0.59 9.0 12.6 0.19 10.7 2.0 3.2 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Effector_1 PF04518.12 KEG07104.1 - 0.81 8.7 6.1 2.9 6.9 1.0 2.3 2 0 0 2 2 2 0 Effector from type III secretion system FlaC_arch PF05377.11 KEG07104.1 - 1 9.8 14.0 10 6.6 0.0 5.0 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KEG07104.1 - 1.1 9.4 13.6 8.5 6.6 0.1 4.3 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family KASH_CCD PF14662.6 KEG07104.1 - 1.8 8.3 30.8 4.4 7.1 7.9 5.0 4 1 0 5 5 5 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 KEG07104.1 - 2.9 7.5 37.4 0.27 10.9 15.8 3.9 4 2 1 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease CENP-K PF11802.8 KEG07104.1 - 3.6 7.1 12.5 2.7 7.5 8.2 2.4 2 0 0 2 2 2 0 Centromere-associated protein K HALZ PF02183.18 KEG07104.1 - 4.2 7.7 11.4 2.1 8.6 2.9 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA_13 PF13166.6 KEG07104.1 - 6.2 5.3 10.5 14 4.1 8.6 2.4 1 1 1 2 2 2 0 AAA domain Prefoldin PF02996.17 KEG07104.1 - 8.9 6.3 16.5 2.4 8.1 0.3 4.8 4 1 1 5 5 5 0 Prefoldin subunit UPF0181 PF03701.14 KEG07105.1 - 0.028 14.1 2.3 3.3 7.4 0.1 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Calpain_inhib PF00748.19 KEG07105.1 - 0.12 12.9 4.4 11 6.6 0.0 4.0 3 0 0 3 3 3 0 Calpain inhibitor FapA PF03961.13 KEG07105.1 - 1.4 7.4 9.3 0.89 8.1 0.2 2.6 2 1 1 3 3 3 0 Flagellar Assembly Protein A SPATA24 PF15175.6 KEG07105.1 - 1.5 8.7 10.2 1.2 9.0 4.5 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Prok-TraM PF09228.10 KEG07105.1 - 8.6 6.8 11.2 9 6.7 0.0 4.6 4 2 0 4 4 4 0 Prokaryotic Transcriptional repressor TraM FtsK_gamma PF09397.10 KEG07106.1 - 0.062 13.1 0.2 0.087 12.6 0.2 1.4 1 1 0 1 1 1 0 Ftsk gamma domain RINGv PF12906.7 KEG07107.1 - 5.2e-13 48.9 11.3 9.8e-13 48.0 11.3 1.5 1 0 0 1 1 1 1 RING-variant domain DUF389 PF04087.14 KEG07107.1 - 0.03 14.4 0.7 0.03 14.4 0.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF389) zf-P11 PF03854.14 KEG07107.1 - 0.063 13.0 0.2 0.18 11.5 0.2 1.8 1 0 0 1 1 1 0 P-11 zinc finger FYVE PF01363.21 KEG07107.1 - 0.13 12.4 3.5 0.72 10.0 0.5 2.6 2 0 0 2 2 2 0 FYVE zinc finger DUF2877 PF11392.8 KEG07107.1 - 0.22 12.2 2.0 3.1 8.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) zf-RING_2 PF13639.6 KEG07107.1 - 0.36 11.2 6.8 0.79 10.1 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KEG07107.1 - 0.77 10.0 4.7 1.5 9.0 4.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KEG07107.1 - 0.87 9.5 7.7 1.8 8.5 7.7 1.6 1 0 0 1 1 1 0 PHD-finger DUF2207 PF09972.9 KEG07107.1 - 1.1 7.9 2.6 0.88 8.3 0.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Band_7 PF01145.25 KEG07108.1 - 1.1e-21 77.6 0.0 1.5e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 KEG07109.1 - 9e-06 25.2 0.0 1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07109.1 - 0.00034 20.0 0.0 0.00037 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APOBEC3 PF18771.1 KEG07109.1 - 0.014 15.5 0.2 0.019 15.1 0.2 1.1 1 0 0 1 1 1 0 APOBEC3 FPRL1_inhibitor PF16104.5 KEG07109.1 - 0.063 13.4 0.2 0.091 12.9 0.2 1.3 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein EVC2_like PF12297.8 KEG07109.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Pkinase PF00069.25 KEG07110.1 - 1.5e-30 106.5 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07110.1 - 5.3e-08 32.5 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG07110.1 - 0.012 14.4 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase AMP-binding PF00501.28 KEG07111.1 - 7.6e-88 294.9 0.0 1e-87 294.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KEG07112.1 - 1.5e-85 287.4 0.0 2.1e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sec7 PF01369.20 KEG07113.1 - 1.3e-57 194.4 0.0 2.8e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 KEG07113.1 - 3.1e-20 71.8 1.9 1.7e-18 66.2 0.0 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 KEG07113.1 - 1.2e-14 54.5 9.0 1.4e-14 54.3 1.5 3.3 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Clathrin_H_link PF13838.6 KEG07113.1 - 0.022 14.7 0.0 3.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Clathrin-H-link MFMR_assoc PF16596.5 KEG07116.1 - 0.017 15.6 5.1 0.017 15.6 5.1 1.8 1 1 1 2 2 2 0 Disordered region downstream of MFMR Neur_chan_memb PF02932.16 KEG07116.1 - 0.71 9.9 5.7 0.89 9.6 5.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPPII_N PF12583.8 KEG07116.1 - 1.5 9.4 6.3 1.9 9.1 5.7 1.4 1 1 0 1 1 1 0 Tripeptidyl peptidase II N terminal TyrRSs_C PF16714.5 KEG07117.1 - 0.033 14.0 0.0 6.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain Prok-E2_D PF14460.6 KEG07117.1 - 0.23 11.1 0.0 27 4.4 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family D LSM PF01423.22 KEG07119.1 - 1.2e-13 50.6 0.7 1.6e-13 50.1 0.7 1.2 1 0 0 1 1 1 1 LSM domain Trypsin_2 PF13365.6 KEG07120.1 - 0.00033 21.6 0.2 0.0005 21.0 0.2 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain PET117 PF15786.5 KEG07122.1 - 6.7e-07 29.5 0.0 8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF3759 PF12585.8 KEG07122.1 - 0.087 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) Ras PF00071.22 KEG07123.1 - 1.7e-36 125.3 0.0 6.1e-36 123.5 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEG07123.1 - 6.3e-23 81.3 0.0 7.1e-22 77.9 0.0 2.0 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG07123.1 - 2.1e-06 27.3 0.0 2.8e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG07123.1 - 0.00017 21.7 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG07123.1 - 0.013 15.4 0.0 0.24 11.3 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KEG07123.1 - 0.04 13.4 0.0 0.089 12.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KEG07123.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region UPF0160 PF03690.13 KEG07124.1 - 1.7e-121 405.7 0.0 2.2e-121 405.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) PrmA PF06325.13 KEG07126.1 - 2.2e-12 47.0 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KEG07126.1 - 4.6e-08 33.7 0.0 2.3e-07 31.4 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Met_10 PF02475.16 KEG07126.1 - 2e-07 30.9 0.0 3.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KEG07126.1 - 3e-06 27.1 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 KEG07126.1 - 6.6e-06 26.7 0.0 2.1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KEG07126.1 - 7.3e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEG07126.1 - 1.7e-05 24.7 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KEG07126.1 - 3.6e-05 23.5 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KEG07126.1 - 5.1e-05 22.9 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KEG07126.1 - 8.8e-05 21.7 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KEG07126.1 - 0.0049 16.7 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEG07126.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KEG07126.1 - 0.02 15.9 0.0 0.068 14.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEG07126.1 - 0.022 15.5 0.0 0.052 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KEG07126.1 - 0.048 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 KEG07126.1 - 0.068 13.1 0.0 0.22 11.4 0.0 1.8 3 0 0 3 3 3 0 Methyltransferase domain TLD PF07534.16 KEG07127.1 - 5.9e-10 39.5 0.0 6e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 TLD Acyl-CoA_dh_1 PF00441.24 KEG07128.1 - 1.4e-52 177.8 1.0 2.4e-52 177.2 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEG07128.1 - 4e-25 88.7 1.4 7.6e-25 87.8 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEG07128.1 - 1.1e-24 87.2 1.0 1.8e-24 86.6 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEG07128.1 - 7.4e-24 83.8 0.0 1.4e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 KEG07128.1 - 0.019 14.6 0.1 0.057 13.1 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cation_ATPase_C PF00689.21 KEG07129.1 - 1.2e-40 139.2 3.1 2.7e-40 138.0 0.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEG07129.1 - 3.4e-33 114.7 2.8 3.4e-33 114.7 2.8 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEG07129.1 - 8.3e-19 67.5 0.0 1.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEG07129.1 - 9.9e-17 61.9 5.1 5.8e-16 59.4 3.6 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEG07129.1 - 1.5e-11 43.8 0.0 3.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEG07129.1 - 9.4e-05 22.3 0.8 0.00021 21.1 0.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MgtE PF01769.16 KEG07129.1 - 0.015 15.7 3.2 0.028 14.8 0.2 2.8 3 0 0 3 3 3 0 Divalent cation transporter DUF1897 PF09005.10 KEG07129.1 - 0.053 13.0 0.5 0.1 12.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) UAA PF08449.11 KEG07136.1 - 1.2e-39 136.3 17.4 2.7e-27 95.8 8.8 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KEG07136.1 - 4.9e-06 26.7 7.1 4.9e-06 26.7 7.1 2.8 2 2 1 3 3 3 1 EamA-like transporter family DUF4126 PF13548.6 KEG07136.1 - 0.0044 16.7 1.7 0.01 15.5 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4126) DUF308 PF03729.13 KEG07136.1 - 0.04 14.2 2.1 19 5.6 0.0 3.3 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DMT_YdcZ PF04657.13 KEG07136.1 - 0.16 12.2 6.1 0.45 10.8 0.4 2.6 2 1 0 2 2 2 0 Putative inner membrane exporter, YdcZ TMEM234 PF10639.9 KEG07136.1 - 0.53 10.3 8.9 0.068 13.2 3.3 2.5 3 0 0 3 3 3 0 Putative transmembrane family 234 Mucin PF01456.17 KEG07137.1 - 0.00021 21.3 11.0 0.00021 21.3 11.0 5.1 1 1 2 3 3 3 1 Mucin-like glycoprotein DUF948 PF06103.11 KEG07138.1 - 0.001 19.3 24.0 0.069 13.4 0.7 4.8 2 1 3 5 5 5 4 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 KEG07138.1 - 0.051 13.3 36.4 0.034 13.9 13.9 3.3 1 1 1 3 3 3 0 Laminin Domain I Phage_prot_Gp6 PF05133.14 KEG07138.1 - 0.058 12.5 7.3 0.55 9.3 7.5 2.1 1 1 1 2 2 2 0 Phage portal protein, SPP1 Gp6-like DUF2316 PF10078.9 KEG07138.1 - 3.4 8.0 5.5 13 6.1 1.7 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) CSN7a_helixI PF18392.1 KEG07138.1 - 7.6 6.5 8.2 0.31 11.0 0.5 2.7 2 1 1 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain Tweety PF04906.13 KEG07139.1 - 3.2 6.3 5.1 0.74 8.4 1.3 1.8 2 0 0 2 2 2 0 Tweety Maf1 PF09174.10 KEG07141.1 - 3.4e-23 82.7 0.0 4.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF3710 PF12502.8 KEG07142.1 - 0.017 14.8 6.2 0.028 14.1 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) Alanine_zipper PF11839.8 KEG07142.1 - 0.021 15.2 4.8 0.021 15.2 4.8 4.9 1 1 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein DUF573 PF04504.14 KEG07142.1 - 0.14 12.8 1.6 0.42 11.3 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Sipho_Gp157 PF05565.11 KEG07142.1 - 0.28 11.2 12.7 0.079 13.0 9.3 1.8 1 1 0 1 1 1 0 Siphovirus Gp157 EMP24_GP25L PF01105.24 KEG07142.1 - 0.57 10.1 4.1 0.85 9.5 4.0 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1771 PF08590.10 KEG07143.1 - 1.1e-18 67.3 10.4 2e-18 66.5 10.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 KEG07143.1 - 4.9e-12 45.5 3.9 8.3e-12 44.8 3.9 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KEG07143.1 - 9.3e-06 25.4 2.9 2.9e-05 23.8 2.9 1.8 1 0 0 1 1 1 1 KH domain SLS PF14611.6 KEG07143.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 KEG07143.1 - 0.16 12.1 0.9 0.36 11.0 0.9 1.6 1 0 0 1 1 1 0 NusA-like KH domain Glyco_hydro_20b PF02838.15 KEG07143.1 - 0.96 10.2 4.1 3.6 8.4 1.7 2.1 1 1 1 2 2 2 0 Glycosyl hydrolase family 20, domain 2 Sun2_CC2 PF18580.1 KEG07143.1 - 6.4 7.1 7.6 26 5.1 0.3 3.2 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Pkinase PF00069.25 KEG07145.1 - 2.9e-68 230.1 0.0 4.1e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07145.1 - 1.2e-41 142.8 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG07145.1 - 3e-06 26.8 0.0 0.082 12.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KEG07145.1 - 0.0015 17.3 0.6 0.0015 17.3 0.6 2.1 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KEG07145.1 - 0.016 15.1 0.1 0.088 12.7 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEG07145.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KEG07145.1 - 0.13 11.9 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF5591 PF17884.1 KEG07145.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) HIT PF01230.23 KEG07148.1 - 2.5e-24 85.8 0.3 3.3e-24 85.5 0.3 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEG07148.1 - 4.6e-13 49.6 0.0 5.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KEG07148.1 - 5.3e-05 23.1 0.3 8.9e-05 22.3 0.3 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 TRAP-gamma PF07074.12 KEG07149.1 - 1.4e-05 24.7 8.4 0.008 15.8 0.8 2.1 1 1 1 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) SieB PF14163.6 KEG07149.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF2976 PF11190.8 KEG07149.1 - 0.12 12.2 0.3 0.5 10.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) VIT_2 PF13757.6 KEG07150.1 - 0.00046 20.0 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT PF08487.10 KEG07150.1 - 0.0027 17.9 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DUF4424 PF14415.6 KEG07150.1 - 0.0058 15.9 0.0 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4424) EBA-175_VI PF11556.8 KEG07154.1 - 0.041 14.2 1.9 0.063 13.6 1.9 1.2 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 DUF4201 PF13870.6 KEG07155.1 - 3.8e-34 118.0 25.3 5.2e-34 117.5 25.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) ZapB PF06005.12 KEG07155.1 - 0.022 15.2 1.7 0.022 15.2 1.7 3.7 2 1 2 4 4 4 0 Cell division protein ZapB Fez1 PF06818.15 KEG07155.1 - 0.12 12.8 19.4 0.087 13.3 17.0 1.9 1 1 1 2 2 2 0 Fez1 Csm1_N PF18504.1 KEG07155.1 - 0.17 12.3 0.4 0.17 12.3 0.4 3.7 3 1 1 4 4 4 0 Csm1 N-terminal domain SOGA PF11365.8 KEG07155.1 - 0.82 10.8 15.8 1 10.5 4.6 3.0 2 1 1 3 3 3 0 Protein SOGA NPV_P10 PF05531.12 KEG07155.1 - 5.1 7.6 7.3 5.1 7.6 0.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 KEG07155.1 - 7.3 6.8 12.6 1.4 9.0 1.1 4.0 4 1 0 4 4 4 0 bZIP transcription factor UPF0242 PF06785.11 KEG07155.1 - 8.3 6.5 21.3 4.5 7.3 12.0 2.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus PX PF00787.24 KEG07156.1 - 4.7e-09 36.2 0.0 1.5e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 PX domain Spt20 PF12090.8 KEG07156.1 - 8.1 6.0 13.5 0.8 9.3 5.3 2.2 2 0 0 2 2 2 0 Spt20 family DUF1467 PF07330.12 KEG07159.1 - 0.06 13.3 0.4 0.077 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DUF1465 PF07323.12 KEG07160.1 - 0.013 15.4 2.4 0.025 14.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Myosin_tail_1 PF01576.19 KEG07160.1 - 0.023 12.5 4.2 0.036 11.9 4.2 1.3 1 0 0 1 1 1 0 Myosin tail YabA PF06156.13 KEG07160.1 - 0.045 14.4 5.3 0.056 14.1 4.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Prominin PF05478.11 KEG07160.1 - 0.062 11.3 2.9 0.076 11.0 2.9 1.0 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.8 KEG07160.1 - 0.12 11.6 7.8 0.22 10.8 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 KEG07160.1 - 0.13 10.9 2.7 0.15 10.6 2.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 KEG07160.1 - 0.88 9.5 9.6 0.56 10.1 6.1 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KEG07160.1 - 0.91 9.7 5.5 2.3 8.5 5.5 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KEG07160.1 - 3.5 8.1 9.3 0.45 11.0 3.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 KEG07162.1 - 1e-26 93.9 0.0 7.6e-26 91.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07162.1 - 1.2e-12 47.6 0.0 4e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Activator_LAG-3 PF11498.8 KEG07162.1 - 9.9 5.0 18.3 18 4.2 18.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF5539 PF17693.1 KEG07163.1 - 0.0097 15.6 3.3 0.012 15.3 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5539) PPR_3 PF13812.6 KEG07164.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Phage_holin_T PF11031.8 KEG07165.1 - 0.0048 16.4 0.0 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 Bacteriophage T holin GTP_EFTU PF00009.27 KEG07167.1 - 1.7e-32 112.6 2.2 3.6e-31 108.2 1.4 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG07167.1 - 4.7e-10 39.5 0.1 9.4e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF-2 PF11987.8 KEG07167.1 - 6.7e-06 26.2 0.0 3.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 SRPRB PF09439.10 KEG07167.1 - 2e-05 24.1 0.0 5.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KEG07167.1 - 0.00095 19.1 0.1 0.25 11.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 KEG07167.1 - 0.0041 16.6 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG07167.1 - 0.0044 17.2 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KEG07167.1 - 0.0099 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KEG07167.1 - 0.0099 15.6 0.1 0.028 14.2 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KEG07167.1 - 0.043 13.9 1.1 3.3 7.8 0.0 2.9 2 1 1 3 3 3 0 Dynamin family PRIMA1 PF16101.5 KEG07171.1 - 0.0012 18.9 5.0 0.0012 18.9 5.0 1.9 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KEG07171.1 - 1 9.4 2.7 1.5 8.9 2.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KEG07171.1 - 1.6 8.1 6.3 2.3 7.6 6.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Umbravirus_LDM PF04817.12 KEG07173.1 - 0.012 15.0 3.2 0.012 15.0 3.2 2.0 1 1 1 2 2 2 0 Umbravirus long distance movement (LDM) family DprA_WH PF17782.1 KEG07174.1 - 0.031 14.4 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 DprA winged helix domain VWA_3_C PF18571.1 KEG07174.1 - 0.066 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain HTH_5 PF01022.20 KEG07174.1 - 0.18 11.7 1.3 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Abhydrolase_6 PF12697.7 KEG07175.1 - 1.5e-12 48.6 0.2 8.5e-12 46.1 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEG07175.1 - 1.2e-10 41.5 0.0 6e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG07175.1 - 2.8e-09 36.6 0.1 8.8e-09 35.0 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KEG07175.1 - 0.0023 17.6 0.3 0.0045 16.7 0.0 1.6 2 0 0 2 2 2 1 Putative esterase DUF676 PF05057.14 KEG07175.1 - 0.0059 16.1 0.0 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KEG07175.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KEG07175.1 - 0.028 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 KEG07175.1 - 0.035 14.0 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydro_lipase PF04083.16 KEG07175.1 - 0.12 12.0 0.1 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region EF-hand_7 PF13499.6 KEG07176.1 - 1.3e-17 64.0 0.4 2.3e-10 40.8 0.7 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG07176.1 - 8.1e-16 56.3 4.9 9.9e-07 27.9 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KEG07176.1 - 2.1e-15 56.3 1.5 0.0023 17.7 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KEG07176.1 - 3e-13 48.5 0.5 3.4e-05 23.4 0.0 5.0 4 1 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 KEG07176.1 - 7.5e-06 26.2 0.2 0.00031 21.0 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KEG07176.1 - 5.8e-05 22.4 1.0 0.0056 16.1 0.0 4.0 4 1 1 5 5 5 1 EF hand EF-hand_4 PF12763.7 KEG07176.1 - 0.00041 20.3 0.1 0.0036 17.2 0.1 1.9 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand GPHH PF16905.5 KEG07176.1 - 0.073 12.9 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SPARC_Ca_bdg PF10591.9 KEG07176.1 - 0.079 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 KEG07176.1 - 0.14 12.3 1.0 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 Ca2+ insensitive EF hand MAM33 PF02330.16 KEG07177.1 - 1.4e-06 28.5 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tctex-1 PF03645.13 KEG07178.1 - 6.9e-22 77.6 0.0 8.5e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Pkinase PF00069.25 KEG07179.1 - 4.7e-57 193.3 0.0 6.9e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07179.1 - 1.1e-17 64.1 0.0 1.4e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG07179.1 - 5.6e-05 23.2 0.1 0.0023 17.9 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG07179.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG07179.1 - 0.029 13.1 0.0 0.68 8.6 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 KEG07179.1 - 0.1 12.2 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Myb_DNA-binding PF00249.31 KEG07181.1 - 4.4e-07 30.0 0.8 0.0035 17.5 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEG07181.1 - 2.8e-06 27.5 1.0 0.0026 18.0 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Secretin_N PF03958.17 KEG07181.1 - 0.13 12.7 2.6 0.99 9.9 0.8 2.5 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain YIF1 PF03878.15 KEG07182.1 - 1.5e-53 181.8 1.1 2e-53 181.4 1.1 1.2 1 0 0 1 1 1 1 YIF1 PRP38 PF03371.15 KEG07183.1 - 5.8e-20 71.9 0.0 8.5e-20 71.3 0.0 1.3 1 1 0 1 1 1 1 PRP38 family DHHC PF01529.20 KEG07184.1 - 7.3 6.7 8.5 1.3 9.1 4.1 1.9 3 0 0 3 3 3 0 DHHC palmitoyltransferase Hid1 PF12722.7 KEG07187.1 - 1.5 6.9 3.5 2 6.4 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spidroin_N PF16763.5 KEG07187.1 - 4.6 7.3 6.3 43 4.1 0.0 2.6 2 1 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term PEX11 PF05648.14 KEG07188.1 - 2.8e-18 66.2 0.6 5.3e-18 65.3 0.6 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) UPF0731 PF14982.6 KEG07189.1 - 0.13 12.5 2.0 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 UPF0731 family Peptidase_M8 PF01457.16 KEG07190.1 - 2.4e-111 373.0 3.8 3.9e-58 197.4 3.4 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG07190.1 - 0.0094 16.1 0.1 0.0094 16.1 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Spc24 PF08286.11 KEG07193.1 - 0.025 14.8 0.3 0.026 14.8 0.3 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 SOGA PF11365.8 KEG07193.1 - 0.025 15.7 0.7 0.027 15.6 0.7 1.1 1 0 0 1 1 1 0 Protein SOGA LPP PF04728.13 KEG07193.1 - 0.039 14.3 2.5 0.059 13.8 2.5 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 KEG07193.1 - 0.05 13.7 5.2 0.073 13.1 5.2 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation MctB PF11382.8 KEG07193.1 - 0.091 12.5 1.1 0.092 12.4 1.1 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF812 PF05667.11 KEG07193.1 - 0.1 11.4 2.6 0.11 11.4 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tex_N PF09371.10 KEG07195.1 - 2.2e-38 131.8 0.2 1.1e-37 129.5 0.0 2.1 2 0 0 2 2 2 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KEG07195.1 - 4.8e-33 114.3 0.2 9.9e-33 113.3 0.2 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 KEG07195.1 - 4.1e-15 56.4 0.2 2.4e-14 54.0 0.1 2.4 2 0 0 2 2 2 1 HHH domain HHH_3 PF12836.7 KEG07195.1 - 4.8e-11 42.8 0.0 1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KEG07195.1 - 2.6e-06 27.3 0.1 7.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KEG07195.1 - 0.00024 21.4 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 KEG07195.1 - 0.00039 20.7 0.1 0.00092 19.5 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF655 PF04919.12 KEG07195.1 - 0.1 12.6 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF655) Latarcin PF10279.9 KEG07195.1 - 1.4 9.4 3.4 2.3 8.7 1.3 2.4 2 0 0 2 2 2 0 Latarcin precursor Phage_holin_1 PF04531.13 KEG07196.1 - 0.24 12.0 1.1 0.3 11.6 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage holin Atg14 PF10186.9 KEG07197.1 - 0.0087 15.2 6.5 0.011 14.8 6.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KEG07197.1 - 0.64 10.0 13.0 0.13 12.2 1.0 2.7 1 1 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 KEG07197.1 - 1.1 9.6 4.8 0.96 9.9 0.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 KEG07197.1 - 2.9 7.7 9.6 10 5.9 6.8 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Tropomyosin_1 PF12718.7 KEG07197.1 - 3.8 7.7 25.6 4.1 7.6 2.8 2.2 1 1 1 2 2 2 0 Tropomyosin like Phage_GP20 PF06810.11 KEG07197.1 - 5.8 6.7 20.9 0.59 9.9 11.4 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Mucin PF01456.17 KEG07198.1 - 0.00028 20.9 6.8 0.016 15.2 6.8 2.3 1 1 0 1 1 1 1 Mucin-like glycoprotein Peptidase_C37 PF05416.12 KEG07198.1 - 0.034 12.7 0.2 0.058 11.9 0.2 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Beta-prism_lec PF16458.5 KEG07198.1 - 0.095 12.7 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 Beta-prism lectin MCLC PF05934.11 KEG07198.1 - 0.16 10.7 1.4 0.2 10.3 1.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF2514 PF10721.9 KEG07198.1 - 2.1 8.3 15.5 0.2 11.7 9.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Mucin PF01456.17 KEG07200.1 - 0.00071 19.6 1.9 0.00096 19.2 1.9 1.3 1 1 0 1 1 1 1 Mucin-like glycoprotein Phage_GPL PF05926.11 KEG07200.1 - 0.032 14.2 0.5 0.056 13.4 0.5 1.4 1 0 0 1 1 1 0 Phage head completion protein (GPL) DUF2514 PF10721.9 KEG07200.1 - 0.04 14.0 5.9 0.037 14.1 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Beta-prism_lec PF16458.5 KEG07200.1 - 0.097 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Beta-prism lectin DUF4574 PF15141.6 KEG07201.1 - 0.042 13.7 1.4 0.058 13.3 1.4 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Mucin PF01456.17 KEG07202.1 - 0.39 10.7 13.2 0.51 10.3 13.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Mucin PF01456.17 KEG07203.1 - 3.1e-05 24.0 61.1 0.041 13.9 24.1 3.7 2 2 0 2 2 2 2 Mucin-like glycoprotein Mucin PF01456.17 KEG07204.1 - 0.033 14.2 65.3 17 5.4 28.7 3.9 1 1 1 2 2 2 0 Mucin-like glycoprotein Mucin PF01456.17 KEG07205.1 - 0.026 14.5 45.5 0.016 15.2 33.1 3.4 2 1 0 2 2 2 0 Mucin-like glycoprotein RsfS PF02410.15 KEG07206.1 - 1.5e-15 57.4 0.5 3e-15 56.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Apolipo_F PF15148.6 KEG07207.1 - 0.033 13.7 0.2 0.064 12.7 0.2 1.6 1 0 0 1 1 1 0 Apolipoprotein F LPP PF04728.13 KEG07207.1 - 0.055 13.9 4.3 4.1 7.9 0.9 4.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 KEG07207.1 - 0.16 12.4 2.2 1.8 9.0 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CC2-LZ PF16516.5 KEG07207.1 - 0.16 12.4 17.4 0.31 11.4 0.5 4.2 3 1 0 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 KEG07207.1 - 0.52 9.5 5.0 0.38 9.9 1.4 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF4200 PF13863.6 KEG07207.1 - 0.94 9.9 19.4 3.2 8.2 1.7 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.6 KEG07207.1 - 2.1 8.8 9.7 0.18 12.2 2.4 2.8 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 FapA PF03961.13 KEG07207.1 - 3.5 6.1 7.6 0.29 9.7 2.7 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A SlyX PF04102.12 KEG07207.1 - 4.8 7.9 16.0 3.1 8.5 0.0 4.4 4 0 0 4 4 4 0 SlyX Rho_Binding PF08912.11 KEG07207.1 - 5.5 7.9 10.8 0.24 12.3 1.8 3.1 3 0 0 3 3 3 0 Rho Binding Cnn_1N PF07989.11 KEG07207.1 - 6.6 7.0 14.5 3.3 7.9 0.8 4.1 4 1 0 4 4 4 0 Centrosomin N-terminal motif 1 zf-B_box PF00643.24 KEG07208.1 - 0.0015 18.6 0.9 0.003 17.7 0.9 1.4 1 0 0 1 1 1 1 B-box zinc finger Spc7 PF08317.11 KEG07208.1 - 0.005 15.8 2.1 0.0083 15.0 2.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5304 PF17230.2 KEG07208.1 - 0.1 12.9 0.8 1.1 9.5 0.1 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5304) Ribosomal_S4e PF00900.20 KEG07208.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal family S4e Rx_N PF18052.1 KEG07208.1 - 0.73 10.1 2.9 1.1 9.6 0.8 2.3 1 1 1 2 2 2 0 Rx N-terminal domain zf-Tim10_DDP PF02953.15 KEG07209.1 - 1 9.1 9.9 0.14 11.9 2.2 2.9 2 1 0 2 2 2 0 Tim10/DDP family zinc finger GPR_Gpa2_C PF11970.8 KEG07210.1 - 0.00024 21.1 1.9 0.00078 19.5 1.9 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ribosomal_S3_C PF00189.20 KEG07212.1 - 1.7e-20 73.3 3.0 2.5e-20 72.8 2.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KEG07212.1 - 1.1e-08 34.8 0.0 3.7e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 KH domain PP2C PF00481.21 KEG07213.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Galactosyl_T PF01762.21 KEG07215.1 - 5.8e-08 32.8 0.0 6.1e-05 22.9 0.0 3.5 3 1 0 3 3 3 1 Galactosyltransferase ESSS PF10183.9 KEG07215.1 - 0.097 12.9 0.0 22 5.3 0.0 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Galactosyl_T PF01762.21 KEG07217.1 - 0.0029 17.4 0.1 0.84 9.4 0.0 2.7 2 1 1 3 3 3 2 Galactosyltransferase Pkinase PF00069.25 KEG07221.1 - 7.4e-22 78.0 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07221.1 - 1.8e-09 37.3 0.0 3.5e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG07221.1 - 0.053 12.8 0.0 0.2 10.9 0.0 1.9 1 1 0 1 1 1 0 Kinase-like RPT PF13446.6 KEG07221.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein RR_TM4-6 PF06459.12 KEG07221.1 - 9.3 6.0 11.4 23 4.7 11.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PUF PF00806.19 KEG07223.1 - 8e-37 122.9 1.8 4.9e-05 22.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-C2H2_assoc2 PF16624.5 KEG07223.1 - 0.022 15.8 9.9 0.076 14.0 9.9 1.9 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger EPL1 PF10513.9 KEG07223.1 - 1.1 9.6 6.1 1.1 9.6 0.8 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like SUIM_assoc PF16619.5 KEG07223.1 - 1.4 9.0 19.3 0.081 13.0 2.7 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Plus-3 PF03126.18 KEG07224.1 - 2.1e-13 50.8 0.0 5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 KEG07224.1 - 6e-10 38.8 10.5 1e-09 38.1 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG07224.1 - 0.0038 17.1 11.1 0.0071 16.2 11.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEG07224.1 - 0.016 15.6 11.8 0.027 14.8 11.8 1.4 1 0 0 1 1 1 0 Ring finger domain DSPn PF14671.6 KEG07225.1 - 5.9e-27 94.8 0.0 3.1e-17 63.4 0.0 3.0 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KEG07225.1 - 5.4e-11 42.4 0.1 5.6e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG07225.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEG07225.1 - 0.0021 18.2 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate SWI-SNF_Ssr4 PF08549.10 KEG07225.1 - 8.7 4.8 9.9 5.4 5.5 0.7 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Mucin PF01456.17 KEG07226.1 - 0.012 15.6 11.0 0.013 15.4 11.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Mucin PF01456.17 KEG07228.1 - 0.00047 20.2 0.2 0.00047 20.2 0.2 3.0 2 1 0 2 2 2 1 Mucin-like glycoprotein Mucin PF01456.17 KEG07229.1 - 9e-05 22.5 29.1 0.032 14.2 12.7 3.2 2 2 0 2 2 2 2 Mucin-like glycoprotein Mit_KHE1 PF10173.9 KEG07229.1 - 0.076 13.1 1.4 0.14 12.3 1.4 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF2524 PF10732.9 KEG07229.1 - 4.5 7.6 6.1 51 4.3 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) COG2 PF06148.11 KEG07229.1 - 6.8 6.8 9.8 6.1 6.9 1.2 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-CCCH_4 PF18044.1 KEG07231.1 - 4.2e-05 23.2 3.4 4.2e-05 23.2 3.4 2.6 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 KEG07231.1 - 0.00013 21.8 9.5 0.043 13.7 1.5 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG07231.1 - 0.0042 17.8 6.0 0.11 13.2 0.1 3.4 3 0 0 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 KEG07231.1 - 0.065 13.3 12.8 0.14 12.3 3.1 3.4 3 0 0 3 3 3 0 Zinc finger domain DUF1206 PF06724.11 KEG07232.1 - 0.1 12.7 1.8 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) CDC45 PF02724.14 KEG07233.1 - 0.0057 15.0 32.5 0.007 14.7 32.5 1.0 1 0 0 1 1 1 1 CDC45-like protein LTV PF04180.14 KEG07233.1 - 0.039 13.7 22.7 0.044 13.5 22.7 1.0 1 0 0 1 1 1 0 Low temperature viability protein BSP_II PF05432.11 KEG07233.1 - 0.045 13.5 24.6 0.059 13.1 24.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) YL1 PF05764.13 KEG07233.1 - 0.23 11.6 36.3 0.28 11.3 36.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 KEG07233.1 - 0.29 9.3 31.3 0.35 9.0 31.3 1.1 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 KEG07233.1 - 0.31 11.0 32.5 0.38 10.7 32.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TFIIF_alpha PF05793.12 KEG07233.1 - 1.9 7.0 30.7 2.4 6.6 30.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vfa1 PF08432.10 KEG07233.1 - 2 8.7 22.7 2.8 8.2 22.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LAP1C PF05609.12 KEG07233.1 - 6.5 5.7 17.7 7.7 5.5 17.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4746 PF15928.5 KEG07233.1 - 6.9 6.0 21.5 8.9 5.6 21.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BSP_II PF05432.11 KEG07234.1 - 0.0079 15.9 3.0 0.0079 15.9 3.0 2.9 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Med8 PF10232.9 KEG07234.1 - 1.8 8.1 13.7 6.6 6.2 0.7 3.3 3 0 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 Pkinase PF00069.25 KEG07236.1 - 2.5e-09 36.9 0.0 2.9e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07236.1 - 0.019 14.3 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KEG07237.1 - 7.6e-14 51.7 0.0 9.8e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KEG07237.1 - 4.8e-05 22.8 0.1 8.5e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KEG07237.1 - 0.035 13.4 0.0 0.58 9.4 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Keratin PF02422.16 KEG07237.1 - 0.16 11.7 2.3 0.47 10.2 2.3 1.8 1 0 0 1 1 1 0 Keratin Host_attach PF10116.9 KEG07237.1 - 0.57 10.8 6.3 1.3 9.6 6.3 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells A_deaminase PF00962.22 KEG07238.1 - 2e-05 24.1 0.7 0.92 8.8 0.0 3.6 3 1 0 3 3 3 3 Adenosine/AMP deaminase MMS1_N PF10433.9 KEG07239.1 - 4.9e-23 81.5 0.0 4.8e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KEG07239.1 - 7.4e-13 48.5 0.0 3.2e-12 46.4 0.0 2.0 2 1 0 2 2 2 1 CPSF A subunit region Ctf8 PF09696.10 KEG07240.1 - 7.5e-22 78.2 1.1 1.5e-21 77.2 1.1 1.4 1 1 0 1 1 1 1 Ctf8 SUIM_assoc PF16619.5 KEG07240.1 - 0.053 13.6 11.1 1.1 9.3 3.1 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 KEG07240.1 - 8.6 7.3 12.2 18 6.2 4.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 NDUF_B7 PF05676.13 KEG07241.1 - 8e-05 22.3 4.5 0.00015 21.4 4.5 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KEG07241.1 - 0.00041 20.3 6.3 0.00041 20.3 6.3 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KEG07241.1 - 0.037 14.0 3.6 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RGI1 PF10843.8 KEG07241.1 - 0.059 13.0 2.8 0.081 12.6 2.8 1.1 1 0 0 1 1 1 0 Respiratory growth induced protein 1 Olfactory_mark PF06554.12 KEG07241.1 - 0.099 12.4 1.3 0.14 11.9 1.3 1.2 1 0 0 1 1 1 0 Olfactory marker protein NPBW PF15180.6 KEG07241.1 - 0.24 11.2 0.2 0.24 11.2 0.2 1.8 2 0 0 2 2 2 0 Neuropeptides B and W Rpn3_C PF08375.11 KEG07241.1 - 0.74 10.3 0.1 0.74 10.3 0.1 2.6 2 1 0 2 2 2 0 Proteasome regulatory subunit C-terminal RNase_H PF00075.24 KEG07243.1 - 0.00086 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 RNase H Glyco_hydro_19 PF00182.19 KEG07243.1 - 0.21 11.5 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Chitinase class I RVT_1 PF00078.27 KEG07245.1 - 0.0094 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amastin PF07344.11 KEG07248.1 - 1.8e-10 40.9 8.2 2.7e-10 40.3 8.2 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 KEG07248.1 - 0.1 12.3 16.2 0.048 13.4 13.1 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KEG07248.1 - 0.1 12.4 14.3 0.25 11.2 14.3 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3619 PF12279.8 KEG07248.1 - 1.3 9.4 5.8 0.79 10.1 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) Ninjurin PF04923.12 KEG07248.1 - 1.6 8.7 18.5 11 6.0 5.7 3.4 2 1 0 3 3 3 0 Ninjurin Phage_holin_3_6 PF07332.11 KEG07248.1 - 5.3 7.1 21.1 0.19 11.8 6.0 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PGG PF13962.6 KEG07248.1 - 6.8 6.5 10.5 0.29 10.9 3.3 2.3 3 0 0 3 3 3 0 Domain of unknown function Trp_oprn_chp PF09534.10 KEG07248.1 - 9.2 6.0 8.2 1.8 8.3 4.8 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PGM_PMM_I PF02878.16 KEG07249.1 - 2.2e-13 50.1 0.1 6.4e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KEG07249.1 - 5.1e-09 36.2 0.0 1.7e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KEG07249.1 - 0.00033 21.2 0.4 0.0025 18.4 0.4 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KEG07249.1 - 0.0075 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RRM_1 PF00076.22 KEG07250.1 - 3.6e-09 36.3 0.0 6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ion_trans_2 PF07885.16 KEG07251.1 - 1.2e-09 38.0 2.3 1.2e-09 38.0 2.3 2.3 2 1 0 2 2 2 1 Ion channel zf-C2H2_4 PF13894.6 KEG07252.1 - 5.7e-05 23.6 1.7 0.00058 20.5 0.6 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger CpXC PF14353.6 KEG07252.1 - 0.00026 21.0 0.4 0.00047 20.2 0.4 1.4 1 0 0 1 1 1 1 CpXC protein GIT_CC PF16559.5 KEG07252.1 - 0.0007 19.4 1.6 0.0018 18.1 0.5 2.0 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor zf-C2H2_jaz PF12171.8 KEG07252.1 - 0.0012 19.1 0.2 0.0049 17.1 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KEG07252.1 - 0.0064 16.9 0.6 0.0064 16.9 0.6 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KEG07252.1 - 0.012 15.6 0.5 0.012 15.6 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KEG07252.1 - 0.029 15.0 0.6 0.071 13.7 0.6 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain zf_UBZ PF18439.1 KEG07252.1 - 0.063 12.9 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Mto2_bdg PF12808.7 KEG07252.1 - 0.094 13.0 3.5 0.18 12.1 3.5 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-H2C2_2 PF13465.6 KEG07252.1 - 0.12 12.8 0.8 0.12 12.8 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.25 KEG07254.1 - 6.5e-62 209.3 0.0 8.3e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07254.1 - 3.9e-42 144.3 0.0 5.8e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG07254.1 - 0.0002 20.3 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG07254.1 - 0.032 14.2 0.1 2.8 7.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEG07254.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.21 KEG07255.1 - 1e-15 57.8 16.6 1e-15 57.8 16.6 1.7 1 1 0 1 1 1 1 Snf7 UCH PF00443.29 KEG07255.1 - 0.085 12.3 1.1 0.1 12.1 1.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FlxA PF14282.6 KEG07255.1 - 0.78 9.8 4.4 2 8.5 3.2 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF4400 PF14348.6 KEG07255.1 - 1.2 8.6 2.7 0.68 9.4 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) FeS_assembly_P PF01883.19 KEG07256.1 - 9.7e-06 25.7 0.1 0.00042 20.4 0.0 2.4 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein TPR_12 PF13424.6 KEG07257.1 - 1.3e-06 28.6 7.4 0.017 15.4 0.6 4.0 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEG07257.1 - 0.0015 18.5 1.6 0.66 10.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEG07257.1 - 0.078 12.9 8.9 0.35 10.8 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Kinesin PF00225.23 KEG07258.1 - 2.9e-14 52.7 1.0 3.3e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 KEG07258.1 - 0.062 13.4 1.3 0.12 12.5 0.2 2.0 1 1 1 2 2 2 0 Kinesin-associated SPATA24 PF15175.6 KEG07258.1 - 0.24 11.3 6.7 0.43 10.5 6.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Atg14 PF10186.9 KEG07258.1 - 0.28 10.2 5.8 0.33 10.0 4.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 KEG07258.1 - 0.29 11.5 9.2 0.81 10.1 9.2 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain Pkinase PF00069.25 KEG07260.1 - 7.8e-47 159.8 0.0 2.6e-46 158.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07260.1 - 9.7e-18 64.4 0.0 3.8e-14 52.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG07260.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG07260.1 - 0.0013 17.6 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG07260.1 - 0.0018 17.7 0.0 0.0067 15.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG07260.1 - 0.0018 18.2 4.2 0.003 17.5 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG07260.1 - 0.0028 16.7 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KEG07260.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KEG07260.1 - 0.04 13.5 0.3 2.7 7.5 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KEG07261.1 - 1.6e-55 188.3 0.0 2.9e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07261.1 - 2.9e-38 131.7 0.0 4.6e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KEG07261.1 - 5.2e-09 36.1 0.1 0.00084 19.4 0.0 3.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KEG07261.1 - 3.2e-08 33.2 0.0 6.2e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PAS PF00989.25 KEG07261.1 - 5e-08 32.9 0.2 3.4e-07 30.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KEG07261.1 - 2.4e-06 27.7 0.3 9.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KEG07261.1 - 0.0027 17.9 0.6 0.0077 16.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold BUD22 PF09073.10 KEG07261.1 - 0.13 11.5 13.7 0.29 10.4 13.7 1.5 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KEG07261.1 - 0.49 9.8 18.2 1 8.8 18.2 1.4 1 0 0 1 1 1 0 SDA1 Tub_N PF16322.5 KEG07261.1 - 5.6 7.3 18.5 7.1 7.0 14.4 2.8 2 0 0 2 2 2 0 Tubby N-terminal RHSP PF07999.11 KEG07263.1 - 2e-71 241.1 0.1 4.6e-60 203.7 0.0 2.3 2 0 0 2 2 2 2 Retrotransposon hot spot protein Macro_2 PF14519.6 KEG07263.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Sigma70_ner PF04546.13 KEG07264.1 - 0.051 13.4 0.6 0.05 13.5 0.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KEG07264.1 - 0.17 12.3 17.3 0.27 11.6 17.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 KEG07264.1 - 0.65 9.6 2.2 0.62 9.6 2.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KEG07264.1 - 0.76 9.0 8.5 1.1 8.6 8.5 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KEG07264.1 - 1.3 8.7 7.2 1.5 8.5 7.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR_4 PF12799.7 KEG07265.1 - 8.8e-23 80.0 22.1 0.00015 22.1 0.2 11.9 8 2 5 14 14 14 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG07265.1 - 6.2e-08 32.3 24.1 0.055 13.2 0.1 8.6 7 3 3 10 10 10 5 Leucine rich repeat LRR_6 PF13516.6 KEG07265.1 - 6.6e-08 32.0 25.7 0.048 13.7 0.0 10.4 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.33 KEG07265.1 - 6.6e-05 22.9 18.2 7.2 7.6 0.1 9.5 8 2 1 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 KEG07265.1 - 0.0051 16.3 3.1 9.6 5.7 0.1 4.3 4 1 1 5 5 5 2 Leucine-rich repeat BT1 PF03092.16 KEG07266.1 - 6.7e-07 27.9 0.1 7.9e-07 27.7 0.1 1.0 1 0 0 1 1 1 1 BT1 family Fim-adh_lectin PF09222.10 KEG07266.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Sec63 PF02889.16 KEG07272.1 - 2.5e-28 98.9 0.0 5e-26 91.4 0.0 2.2 1 1 0 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.31 KEG07272.1 - 0.00079 19.7 0.0 0.0025 18.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KEG07272.1 - 0.00095 19.7 0.0 0.0024 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KEG07272.1 - 0.0059 16.8 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KEG07272.1 - 0.0092 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DUF4332 PF14229.6 KEG07272.1 - 0.024 14.8 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Deltameth_res PF16020.5 KEG07272.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Deltamethrin resistance Inhibitor_I29 PF08246.12 KEG07273.1 - 3.1e-09 37.1 0.0 4.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PepSY_2 PF13670.6 KEG07273.1 - 0.26 11.3 0.1 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Glyco_transf_15 PF01793.16 KEG07274.1 - 6.1e-37 127.6 0.0 7.1e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 KEG07275.1 - 0.00081 20.2 0.0 3.8 8.5 0.2 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat DBD_Tnp_Mut PF03108.15 KEG07275.1 - 0.051 13.6 0.0 0.5 10.4 0.0 2.5 2 0 0 2 2 2 0 MuDR family transposase UCH PF00443.29 KEG07277.1 - 1e-40 139.9 0.0 4.7e-39 134.4 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG07277.1 - 1.4e-14 54.4 2.3 4.1e-13 49.6 0.2 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TFIIA PF03153.13 KEG07277.1 - 0.29 11.1 6.6 0.4 10.6 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 KEG07278.1 - 0.00065 20.0 0.0 0.0045 17.3 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG07278.1 - 0.44 11.5 10.6 11 7.1 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat Pkinase PF00069.25 KEG07279.1 - 1.5e-16 60.6 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07279.1 - 2.2e-07 30.4 0.0 0.00039 19.8 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KEG07279.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG07279.1 - 0.051 13.5 0.1 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG07279.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KEG07279.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Mucin PF01456.17 KEG07286.1 - 0.089 12.8 19.0 0.17 11.9 19.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 KEG07286.1 - 0.17 10.0 2.0 0.21 9.7 2.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RNase_PH_C PF03725.15 KEG07287.1 - 8.7e-05 22.5 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Androgen_recep PF02166.16 KEG07289.1 - 0.01 14.7 1.4 0.01 14.7 1.4 2.3 3 1 0 3 3 3 0 Androgen receptor SUIM_assoc PF16619.5 KEG07289.1 - 4.7 7.3 17.4 0.24 11.5 2.3 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 HMG_box PF00505.19 KEG07290.1 - 1.6e-07 31.7 0.4 0.0069 16.8 0.4 3.9 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEG07290.1 - 0.0005 20.6 0.9 0.0047 17.5 0.1 2.8 3 1 0 3 3 3 1 HMG-box domain DUF2057 PF09829.9 KEG07290.1 - 0.012 15.8 0.9 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TerB_C PF15615.6 KEG07291.1 - 0.83 9.9 5.0 0.18 12.1 1.4 1.6 2 0 0 2 2 2 0 TerB-C domain Mucin PF01456.17 KEG07292.1 - 0.0027 17.7 13.1 0.0027 17.7 13.1 3.8 2 2 1 3 3 3 2 Mucin-like glycoprotein DUF5343 PF17278.2 KEG07293.1 - 0.0069 16.5 0.1 0.0069 16.5 0.1 2.8 2 1 1 3 3 3 1 Family of unknown function (DUF5343) Alanine_zipper PF11839.8 KEG07293.1 - 0.025 14.9 77.8 0.041 14.3 13.1 4.9 3 2 1 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein VGCC_beta4Aa_N PF12052.8 KEG07293.1 - 0.035 14.2 2.5 1.9 8.7 0.0 3.2 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal LXG PF04740.12 KEG07293.1 - 0.58 9.8 25.4 0.025 14.3 7.9 3.2 1 1 2 3 3 3 0 LXG domain of WXG superfamily PSCyt1 PF07635.11 KEG07293.1 - 1.6 9.4 3.5 2 9.0 0.1 2.9 3 0 0 3 3 3 0 Planctomycete cytochrome C GARP PF16731.5 KEG07293.1 - 3.7 7.2 61.3 0.5 10.0 21.1 3.9 1 1 2 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma ABC2_membrane_3 PF12698.7 KEG07295.1 - 2.8e-38 131.9 21.3 5.7e-38 130.9 21.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEG07295.1 - 0.062 12.6 10.9 0.14 11.4 10.9 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein LapA_dom PF06305.11 KEG07295.1 - 0.56 10.1 3.7 0.99 9.3 2.4 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 KEG07296.1 - 3.5e-21 76.2 0.0 5.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG07296.1 - 1.2e-10 41.8 0.1 9.5e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system KdpD PF02702.17 KEG07296.1 - 0.0049 16.4 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain SRP54 PF00448.22 KEG07296.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KEG07296.1 - 0.062 12.6 0.0 8.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF4162 PF13732.6 KEG07296.1 - 0.1 13.3 0.0 0.25 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) SMC_N PF02463.19 KEG07296.1 - 0.16 11.3 0.0 1.6 8.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dala_Dala_lig_N PF01820.21 KEG07297.1 - 0.054 14.0 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus ABC2_membrane_3 PF12698.7 KEG07298.1 - 1.8e-05 24.0 0.0 0.001 18.2 0.1 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF2370 PF10176.9 KEG07298.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) HDV_ag PF01517.18 KEG07299.1 - 0.005 16.7 2.4 0.011 15.5 2.4 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen DUF3713 PF12506.8 KEG07299.1 - 0.019 15.3 0.5 0.019 15.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) YscO PF07321.12 KEG07301.1 - 5.7 6.9 37.4 0.18 11.7 9.0 3.5 3 1 0 3 3 3 0 Type III secretion protein YscO E1-N PF14463.6 KEG07303.1 - 0.03 14.2 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 E1 N-terminal domain N6-adenineMlase PF10237.9 KEG07307.1 - 3.3e-35 121.2 0.0 6.8e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Spectrin PF00435.21 KEG07307.1 - 0.027 15.0 0.4 0.027 15.0 0.4 3.4 3 0 0 3 3 3 0 Spectrin repeat RAB3GAP2_N PF14655.6 KEG07307.1 - 0.035 13.4 0.4 0.053 12.8 0.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_23 PF13476.6 KEG07307.1 - 0.043 14.3 3.8 0.03 14.8 2.0 1.5 1 1 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 KEG07307.1 - 0.087 12.7 0.2 1.4 8.7 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Codanin-1_C PF15296.6 KEG07309.1 - 0.077 13.1 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Codanin-1 C-terminus DUF4726 PF15855.5 KEG07309.1 - 0.4 10.9 4.2 0.21 11.8 2.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) HA2 PF04408.23 KEG07311.1 - 1.1e-13 51.4 1.9 8.7e-13 48.5 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEG07311.1 - 1.1e-11 45.0 0.0 2.4e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEG07311.1 - 2.6e-08 34.2 0.0 7.5e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG07311.1 - 9.4e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEG07311.1 - 0.001 19.4 0.6 0.0065 16.7 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG07311.1 - 0.019 15.3 0.1 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEG07311.1 - 0.029 13.4 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KEG07311.1 - 0.032 14.7 13.2 0.18 12.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 KEG07311.1 - 0.098 12.6 0.2 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_11 PF13086.6 KEG07311.1 - 0.36 10.6 13.6 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEG07311.1 - 1.3 8.6 3.5 0.56 9.8 0.2 2.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MHC_I_C PF06623.11 KEG07313.1 - 0.14 12.1 1.3 0.28 11.1 1.3 1.6 1 0 0 1 1 1 0 MHC_I C-terminus NgoMIV_restric PF09015.10 KEG07313.1 - 0.23 10.5 0.1 0.31 10.1 0.1 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme DUF905 PF06006.12 KEG07314.1 - 0.055 13.5 1.7 1.9 8.6 0.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF905) Herpes_PAP PF03325.13 KEG07319.1 - 0.12 12.0 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein ApbE PF02424.15 KEG07321.1 - 1.8e-05 24.4 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ApbE family MMS22L_C PF14911.6 KEG07322.1 - 0.024 13.7 0.9 0.056 12.5 0.9 1.5 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal DUF445 PF04286.12 KEG07322.1 - 0.046 13.5 0.4 0.072 12.9 0.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF445) ComP_DUS PF16732.5 KEG07322.1 - 0.076 13.9 0.3 0.26 12.2 0.1 1.9 2 0 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor Cas_Csa5 PF09702.10 KEG07322.1 - 0.091 13.0 0.4 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Csa5) DUF760 PF05542.11 KEG07322.1 - 0.12 12.8 1.6 8.2 6.9 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF760) DUF4795 PF16043.5 KEG07322.1 - 0.44 10.1 4.4 0.13 11.9 0.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) MRP-S28 PF10213.9 KEG07325.1 - 0.0018 18.7 0.0 0.0041 17.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Lon_2 PF13337.6 KEG07325.1 - 0.097 11.2 0.1 0.17 10.4 0.1 1.3 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease NAC PF01849.18 KEG07327.1 - 3.8e-14 52.4 0.0 7.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 NAC domain Tmemb_185A PF10269.9 KEG07329.1 - 2.1e-22 80.0 10.9 5.8e-22 78.6 10.9 1.7 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 KEG07329.1 - 1.5e-20 73.0 0.0 2.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF963 PF06131.11 KEG07330.1 - 1 8.8 5.6 0.32 10.5 0.2 2.4 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ApoO PF09769.9 KEG07336.1 - 0.094 12.7 2.2 0.22 11.5 0.2 2.2 2 0 0 2 2 2 0 Apolipoprotein O EMC3_TMCO1 PF01956.16 KEG07336.1 - 0.8 9.4 1.5 34 4.1 0.0 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF3367 PF11847.8 KEG07336.1 - 1.6 6.5 10.5 1.9 6.2 10.5 1.3 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Fib_alpha PF08702.10 KEG07336.1 - 2.8 8.1 5.7 2.1 8.6 0.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KEG07336.1 - 3.7 7.8 9.4 0.81 10.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KEG07336.1 - 4.5 7.3 5.9 0.66 10.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SesA PF17107.5 KEG07336.1 - 8.1 6.7 8.8 9.6 6.4 2.0 2.3 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Mucin PF01456.17 KEG07337.1 - 6.5e-06 26.2 0.8 0.00095 19.2 0.0 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF2201_N PF13203.6 KEG07337.1 - 0.019 14.5 0.7 0.028 14.0 0.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF5486 PF17588.2 KEG07337.1 - 0.16 11.8 1.2 0.5 10.3 0.3 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5486) ISG65-75 PF11727.8 KEG07337.1 - 6.2 6.0 7.9 1.1 8.5 3.7 1.7 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF3665 PF12427.8 KEG07340.1 - 0.018 14.7 0.5 0.038 13.7 0.5 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase ABC_tran PF00005.27 KEG07341.1 - 2.6e-63 212.6 0.0 4.9e-25 88.6 0.0 3.3 2 1 1 3 3 3 3 ABC transporter ABC2_membrane_3 PF12698.7 KEG07341.1 - 1.1e-54 185.8 54.2 5.8e-45 153.9 16.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KEG07341.1 - 6.5e-17 62.3 6.2 6.6e-06 26.2 0.0 5.1 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEG07341.1 - 6.5e-09 36.6 0.7 0.039 14.5 0.0 3.3 3 0 0 3 3 3 3 AAA domain RsgA_GTPase PF03193.16 KEG07341.1 - 1.1e-06 28.7 0.4 0.0042 17.0 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KEG07341.1 - 1.2e-06 28.2 2.2 0.035 13.9 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain SRP54 PF00448.22 KEG07341.1 - 2.3e-06 27.4 3.1 0.0054 16.4 0.0 3.2 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KEG07341.1 - 1.6e-05 24.3 1.2 2.6 7.3 0.1 4.2 4 0 0 4 4 4 1 Zeta toxin SMC_N PF02463.19 KEG07341.1 - 2.1e-05 24.0 0.0 5.2 6.4 0.0 4.0 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEG07341.1 - 2.3e-05 24.2 1.6 0.29 10.8 0.2 3.4 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 KEG07341.1 - 0.00013 22.1 0.2 1.2 9.5 0.0 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KEG07341.1 - 0.00085 19.4 0.3 2.4 8.2 0.1 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG07341.1 - 0.0029 18.0 0.1 4 7.8 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_15 PF13175.6 KEG07341.1 - 0.0039 17.0 0.0 1 9.0 0.0 3.7 5 0 0 5 5 5 1 AAA ATPase domain MobB PF03205.14 KEG07341.1 - 0.024 14.5 0.7 16 5.4 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KEG07341.1 - 0.03 14.2 0.2 8.6 6.2 0.0 3.2 2 1 1 3 3 3 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KEG07341.1 - 0.032 14.6 2.9 16 5.9 0.1 3.6 3 0 0 3 3 3 0 RNA helicase KdpD PF02702.17 KEG07341.1 - 0.039 13.4 0.3 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA PF00004.29 KEG07341.1 - 0.044 14.2 3.1 4 7.9 0.0 3.7 3 1 1 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KEG07341.1 - 0.046 12.4 1.4 3.5 6.2 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KEG07341.1 - 0.047 13.9 0.8 22 5.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KEG07341.1 - 0.092 12.3 5.4 2.8 7.5 0.2 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KEG07341.1 - 0.11 12.4 2.8 10 6.1 0.1 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 KEG07341.1 - 0.17 10.7 4.4 0.63 8.8 0.2 2.5 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) AAA_27 PF13514.6 KEG07341.1 - 0.2 11.2 0.6 23 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KEG07341.1 - 0.33 10.7 2.2 18 5.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KEG07341.1 - 0.39 11.0 3.3 9.5 6.5 0.1 3.7 3 1 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 KEG07341.1 - 0.46 10.1 1.4 74 2.9 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase MukB PF04310.12 KEG07341.1 - 0.48 10.2 5.6 8.4 6.1 0.1 3.1 3 0 0 3 3 3 0 MukB N-terminal AAA_28 PF13521.6 KEG07341.1 - 0.48 10.7 3.7 12 6.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain Tmemb_9 PF05434.11 KEG07341.1 - 0.48 10.3 5.4 7.1 6.5 0.0 2.8 2 0 0 2 2 2 0 TMEM9 FeoB_N PF02421.18 KEG07341.1 - 0.68 9.5 5.2 5.1 6.6 0.2 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KEG07341.1 - 0.98 9.1 5.4 14 5.4 0.2 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Fibrillarin PF01269.17 KEG07343.1 - 1.4e-98 328.6 0.0 1.5e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KEG07343.1 - 1.7e-07 31.2 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 KEG07343.1 - 0.0017 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Lar_N PF09861.9 KEG07343.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Lactate racemase N-terminal domain FtsJ PF01728.19 KEG07343.1 - 0.088 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DnaJ PF00226.31 KEG07344.1 - 9e-05 22.5 8.7 0.043 13.9 4.5 3.5 3 1 0 3 3 3 2 DnaJ domain DnaJ PF00226.31 KEG07345.1 - 6e-18 64.7 1.9 6.2e-18 64.7 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain SH3_9 PF14604.6 KEG07346.1 - 1.5e-07 31.1 0.1 2.8e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEG07346.1 - 0.00019 20.9 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEG07346.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain S-methyl_trans PF02574.16 KEG07347.1 - 2.2e-39 135.9 0.0 3.3e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Nsp1_C PF05064.13 KEG07348.1 - 0.028 14.2 2.1 0.059 13.2 2.1 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region CENP-B_dimeris PF09026.10 KEG07348.1 - 5.9 7.3 13.5 5.1 7.5 10.4 2.5 4 0 0 4 4 4 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KEG07348.1 - 8.3 6.1 14.4 6.6 6.4 10.7 2.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 KEG07349.1 - 3.9e-20 71.4 0.1 1.3e-14 53.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ciart PF15673.5 KEG07349.1 - 0.085 12.2 0.7 0.15 11.4 0.7 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor CRAL_TRIO PF00650.20 KEG07350.1 - 8.2e-31 106.9 0.0 1.2e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KEG07350.1 - 0.0018 18.5 0.0 0.0061 16.7 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain UCH PF00443.29 KEG07351.1 - 1e-29 103.8 0.0 1.9e-29 102.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG07351.1 - 1.8e-09 37.6 0.1 0.00039 20.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PHTB1_N PF14727.6 KEG07352.1 - 1.9e-114 383.2 0.0 2.6e-114 382.8 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KEG07352.1 - 7.3e-87 291.9 0.0 1.1e-86 291.3 0.0 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus Peptidase_M8 PF01457.16 KEG07354.1 - 1.9e-113 380.0 9.1 4.1e-60 204.0 4.4 2.1 2 0 0 2 2 2 2 Leishmanolysin zf-MIZ PF02891.20 KEG07354.1 - 0.013 15.3 0.1 0.096 12.5 0.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Reprolysin_5 PF13688.6 KEG07354.1 - 0.059 13.5 0.1 0.059 13.5 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12 Podoplanin PF05808.11 KEG07354.1 - 3 7.9 11.1 6.3 6.9 11.1 1.5 1 0 0 1 1 1 0 Podoplanin MACPF PF01823.19 KEG07357.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 MAC/Perforin domain PI3K_C2 PF00792.24 KEG07359.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 ASCH PF04266.14 KEG07360.1 - 2.4e-14 53.8 0.0 5.9e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 KEG07360.1 - 2.8e-06 27.2 8.4 5.8e-06 26.2 8.4 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SH3-RhoG_link PF16609.5 KEG07360.1 - 0.055 13.2 0.5 0.15 11.8 0.5 1.7 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region NAD_binding_9 PF13454.6 KEG07360.1 - 0.13 12.2 1.3 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4672 PF15716.5 KEG07360.1 - 0.2 11.3 0.8 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) His_Phos_1 PF00300.22 KEG07361.1 - 2.1e-39 135.3 0.1 2.2e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Toprim_3 PF13362.6 KEG07361.1 - 0.042 14.2 0.1 4 7.9 0.1 2.3 2 1 0 2 2 2 0 Toprim domain Synaptobrevin PF00957.21 KEG07363.1 - 3.7e-31 106.8 3.8 6.2e-31 106.1 3.8 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEG07363.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain EMP24_GP25L PF01105.24 KEG07363.1 - 0.005 16.8 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4844 PF16133.5 KEG07363.1 - 0.047 14.2 1.4 0.12 12.9 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) FtsK_SpoIIIE PF01580.18 KEG07363.1 - 0.087 12.2 0.3 0.14 11.5 0.3 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mucin PF01456.17 KEG07364.1 - 0.00074 19.5 2.5 0.00074 19.5 2.5 3.7 2 1 0 2 2 2 1 Mucin-like glycoprotein DUF2884 PF11101.8 KEG07364.1 - 0.17 11.4 1.2 7.2 6.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Mucin PF01456.17 KEG07365.1 - 0.0036 17.3 22.4 0.018 15.1 8.5 2.6 2 1 0 2 2 2 2 Mucin-like glycoprotein PepSY_TM PF03929.16 KEG07365.1 - 0.013 15.2 1.3 0.027 14.1 0.0 2.0 2 1 0 2 2 2 0 PepSY-associated TM region Hydrolase_6 PF13344.6 KEG07365.1 - 0.018 15.1 1.4 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ferritin PF00210.24 KEG07365.1 - 0.099 12.6 2.0 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 Ferritin-like domain Shisa PF13908.6 KEG07365.1 - 0.72 10.1 3.1 0.52 10.5 0.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FliL PF03748.14 KEG07366.1 - 0.13 12.8 0.2 0.33 11.6 0.2 1.8 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL Baculo_PEP_C PF04513.12 KEG07367.1 - 4.6e-05 23.5 38.2 0.1 12.6 2.1 9.5 6 2 4 10 10 10 4 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KEG07367.1 - 0.0002 20.4 10.6 0.0002 20.4 10.6 8.1 2 2 2 7 7 7 5 Spc7 kinetochore protein MIP-T3_C PF17749.1 KEG07367.1 - 0.00046 20.2 3.1 0.00046 20.2 3.1 6.5 5 3 2 7 7 7 1 Microtubule-binding protein MIP-T3 C-terminal region Laminin_II PF06009.12 KEG07367.1 - 0.023 14.7 0.4 0.023 14.7 0.4 9.9 5 3 3 10 10 10 0 Laminin Domain II Fib_alpha PF08702.10 KEG07367.1 - 0.51 10.5 56.1 1.2 9.3 7.5 8.5 5 3 2 8 8 8 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KEG07367.1 - 1.1 9.8 35.1 0.61 10.6 0.8 9.8 6 4 2 10 10 10 0 Nucleopolyhedrovirus P10 protein FAD_SOX PF18371.1 KEG07367.1 - 3.2 8.2 6.7 20 5.6 0.1 5.0 4 2 1 5 5 5 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF1664 PF07889.12 KEG07367.1 - 7.9 6.5 60.9 2.7 8.0 1.7 10.6 8 5 4 12 12 12 0 Protein of unknown function (DUF1664) Esterase PF00756.20 KEG07368.1 - 0.02 14.5 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative esterase CN_hydrolase PF00795.22 KEG07369.1 - 1.5e-52 178.6 0.0 1.6e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Arf PF00025.21 KEG07371.1 - 2.6e-48 163.7 0.0 3.1e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEG07371.1 - 1.2e-12 47.7 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEG07371.1 - 3.2e-10 39.7 1.2 4.9e-06 26.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KEG07371.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEG07371.1 - 2.2e-08 34.2 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KEG07371.1 - 3e-08 33.4 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KEG07371.1 - 5.7e-05 22.7 0.1 0.0018 17.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEG07371.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KEG07371.1 - 0.0022 17.9 0.0 1.5 8.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KEG07371.1 - 0.0022 17.5 0.2 0.0059 16.1 0.1 1.8 2 1 0 2 2 2 1 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 KEG07371.1 - 0.13 11.6 0.4 2.1 7.7 0.1 2.4 1 1 2 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KEG07371.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEG07371.1 - 0.17 12.2 0.1 0.44 10.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain LSM PF01423.22 KEG07372.1 - 0.0019 17.8 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain Amidase PF01425.21 KEG07373.1 - 1.8e-63 215.1 0.0 5.3e-62 210.2 0.0 2.0 1 1 0 1 1 1 1 Amidase RCC1 PF00415.18 KEG07374.1 - 6e-12 46.0 13.8 0.0003 21.3 0.7 5.4 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG07374.1 - 9.4e-08 31.7 5.1 0.017 15.0 0.1 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.24 KEG07375.1 - 3e-31 108.8 0.0 4.4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.12 KEG07376.1 - 1.5e-66 224.5 0.0 2.3e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KEG07376.1 - 1.3e-22 79.9 0.1 3e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Tudor_1_RapA PF18339.1 KEG07376.1 - 0.049 13.6 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain 1 YabA PF06156.13 KEG07377.1 - 0.018 15.7 8.2 0.26 11.9 1.8 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Vac_Fusion PF02346.16 KEG07377.1 - 0.019 14.6 0.8 0.091 12.4 0.2 2.3 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 TFIIA PF03153.13 KEG07377.1 - 0.081 12.9 3.3 0.094 12.7 3.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HALZ PF02183.18 KEG07377.1 - 0.12 12.6 6.4 0.3 11.3 1.0 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper EMP24_GP25L PF01105.24 KEG07377.1 - 0.89 9.5 2.8 8.8 6.2 3.1 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD GAS PF13851.6 KEG07377.1 - 6.7 6.0 18.6 0.067 12.5 8.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3357 PF11837.8 KEG07379.1 - 0.16 12.5 0.7 0.47 10.9 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) O-FucT PF10250.9 KEG07380.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DUF3558 PF12079.8 KEG07381.1 - 0.023 14.7 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) TIMELESS_C PF05029.13 KEG07381.1 - 0.23 10.5 10.6 0.27 10.3 10.6 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region Exo_endo_phos_2 PF14529.6 KEG07382.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KEG07383.1 - 4.7e-35 121.1 0.0 5.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PUFD PF16553.5 KEG07384.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.3 1 1 0 1 1 1 0 BCORL-PCGF1-binding domain RhoGAP PF00620.27 KEG07385.1 - 0.017 15.0 0.1 0.056 13.3 0.1 1.9 2 0 0 2 2 2 0 RhoGAP domain ZapB PF06005.12 KEG07385.1 - 8.1 7.0 17.1 33 5.0 2.9 4.2 3 1 0 3 3 3 0 Cell division protein ZapB PH PF00169.29 KEG07386.1 - 0.0022 18.5 0.0 0.005 17.3 0.0 1.6 1 0 0 1 1 1 1 PH domain RL10P_insert PF17777.1 KEG07387.1 - 3.7e-21 74.9 0.1 8e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KEG07387.1 - 8.8e-16 58.3 7.5 1.8e-15 57.3 7.5 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 KEG07387.1 - 3.4e-14 52.8 0.1 6.6e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Pkinase PF00069.25 KEG07388.1 - 5.2e-58 196.5 0.0 7.3e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07388.1 - 4.9e-37 127.6 0.0 1.1e-36 126.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEG07388.1 - 4.6e-05 23.5 0.0 0.00038 20.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG07388.1 - 0.00064 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KEG07388.1 - 0.0015 17.9 0.0 0.0052 16.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG07388.1 - 0.0026 16.6 0.1 0.007 15.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KEG07388.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEG07388.1 - 0.0076 15.3 0.2 0.016 14.3 0.2 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KEG07388.1 - 0.037 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain NOA36 PF06524.12 KEG07388.1 - 0.2 11.0 8.5 0.31 10.3 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3245 PF11595.8 KEG07388.1 - 7.2 7.1 8.5 4.4 7.8 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) LicD PF04991.13 KEG07389.1 - 0.00061 20.0 0.2 0.03 14.4 0.3 2.2 2 0 0 2 2 2 2 LicD family AAA_23 PF13476.6 KEG07390.1 - 0.76 10.2 20.8 1.1 9.7 20.8 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 KEG07390.1 - 1.4 7.1 10.6 1.5 7.0 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 KEG07390.1 - 5.3 5.6 16.1 6.7 5.3 16.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WW PF00397.26 KEG07391.1 - 1.3e-08 34.7 0.4 2.5e-08 33.8 0.4 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.11 KEG07393.1 - 0.00054 20.2 20.9 0.00054 20.2 20.9 8.1 2 2 5 7 7 7 1 Autophagy protein 16 (ATG16) DUF2935 PF11155.8 KEG07393.1 - 0.0031 17.9 0.4 3.6 8.0 0.0 4.8 3 2 0 3 3 3 1 Domain of unknown function (DUF2935) CCDC106 PF15794.5 KEG07393.1 - 0.011 15.5 2.8 0.011 15.5 2.8 6.5 4 2 1 6 6 6 0 Coiled-coil domain-containing protein 106 Scaffolding_pro PF11418.8 KEG07393.1 - 0.23 12.0 10.1 8.6 7.0 0.1 5.2 3 1 1 4 4 4 0 Phi29 scaffolding protein TLE_N PF03920.15 KEG07393.1 - 0.34 11.0 0.0 0.34 11.0 0.0 5.2 4 1 1 5 5 5 0 Groucho/TLE N-terminal Q-rich domain BLOC1_2 PF10046.9 KEG07393.1 - 0.72 10.2 31.0 1.3 9.3 0.7 7.3 6 1 1 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 KEG07393.1 - 2.4 8.3 31.1 2.6 8.2 0.6 8.5 6 3 3 9 9 9 0 bZIP transcription factor DUF717 PF05338.12 KEG07394.1 - 0.066 13.4 0.1 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF717) Rtf2 PF04641.12 KEG07396.1 - 0.074 12.4 0.2 0.074 12.4 0.2 3.3 3 1 0 3 3 3 0 Rtf2 RING-finger SUIM_assoc PF16619.5 KEG07396.1 - 0.59 10.2 25.9 0.52 10.4 5.8 4.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Atx10homo_assoc PF09759.9 KEG07398.1 - 0.039 14.0 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain LAT PF15234.6 KEG07398.1 - 0.15 11.8 0.4 0.27 11.0 0.4 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells MFS_1 PF07690.16 KEG07399.1 - 3.2e-16 59.2 23.5 3.2e-16 59.2 23.5 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG07399.1 - 8.1e-16 58.3 16.6 8.1e-16 58.3 16.6 2.5 2 1 0 2 2 2 1 Nodulin-like DUF1129 PF06570.11 KEG07399.1 - 2.3 7.7 4.5 3.3 7.2 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3767 PF12597.8 KEG07399.1 - 2.9 7.7 5.8 0.93 9.4 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) LRR_6 PF13516.6 KEG07400.1 - 2.1e-07 30.4 4.5 0.00021 21.1 0.2 4.4 4 1 1 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 KEG07400.1 - 0.035 13.8 0.5 20 5.0 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat UPF0564 PF10595.9 KEG07401.1 - 4.8e-05 22.6 20.1 4.8e-05 22.6 20.1 3.1 2 1 1 3 3 3 2 Uncharacterised protein family UPF0564 DUF4071 PF13281.6 KEG07401.1 - 0.16 11.0 5.6 0.26 10.3 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Lipoxygenase PF00305.19 KEG07401.1 - 0.17 10.3 3.6 0.24 9.8 3.6 1.1 1 0 0 1 1 1 0 Lipoxygenase DUF4307 PF14155.6 KEG07403.1 - 0.081 12.8 2.4 0.11 12.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Mrr_cat PF04471.12 KEG07403.1 - 0.13 12.3 0.4 0.16 12.0 0.4 1.1 1 0 0 1 1 1 0 Restriction endonuclease PPTA PF01239.22 KEG07405.1 - 7.9e-05 22.3 3.4 0.00021 20.9 0.2 2.5 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat CLP1_P PF16575.5 KEG07407.1 - 1.2e-26 93.7 0.0 3.1e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KEG07407.1 - 0.0057 17.0 0.7 0.016 15.6 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KEG07407.1 - 0.012 16.1 0.1 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KEG07407.1 - 0.064 13.2 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KEG07407.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KEG07407.1 - 0.074 13.3 0.6 0.33 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEG07407.1 - 0.096 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KEG07407.1 - 0.099 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEG07407.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KEG07407.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 KEG07410.1 - 0.00032 19.9 1.7 0.00037 19.7 1.7 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 KEG07410.1 - 0.0031 16.5 4.1 0.004 16.1 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CdvA PF18822.1 KEG07410.1 - 0.0065 16.3 5.5 0.014 15.3 5.2 1.6 1 1 0 1 1 1 1 CdvA-like coiled-coil domain Prominin PF05478.11 KEG07410.1 - 0.011 13.7 3.3 0.014 13.4 3.3 1.0 1 0 0 1 1 1 0 Prominin EMP24_GP25L PF01105.24 KEG07410.1 - 0.022 14.7 2.1 0.042 13.8 2.1 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Troponin PF00992.20 KEG07410.1 - 0.022 15.1 5.8 0.037 14.3 5.8 1.3 1 0 0 1 1 1 0 Troponin Prefoldin_2 PF01920.20 KEG07410.1 - 0.029 14.3 4.0 0.029 14.3 4.0 1.9 1 1 0 1 1 1 0 Prefoldin subunit Myosin_tail_1 PF01576.19 KEG07410.1 - 0.032 12.1 6.0 0.043 11.6 6.0 1.1 1 0 0 1 1 1 0 Myosin tail FapA PF03961.13 KEG07410.1 - 0.047 12.3 4.4 0.065 11.8 4.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tho2 PF11262.8 KEG07410.1 - 0.069 12.3 8.2 0.099 11.8 8.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Herpes_UL6 PF01763.16 KEG07410.1 - 0.093 11.2 2.5 0.12 10.9 2.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FlaC_arch PF05377.11 KEG07410.1 - 0.095 13.1 2.3 0.25 11.8 2.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 KEG07410.1 - 0.33 10.8 8.3 0.58 10.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 KEG07410.1 - 0.49 9.6 7.6 0.66 9.2 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein GIT_CC PF16559.5 KEG07410.1 - 0.7 9.8 8.5 0.23 11.3 4.9 2.0 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KEG07410.1 - 0.81 10.4 7.0 2.2 9.0 7.0 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DUF3450 PF11932.8 KEG07410.1 - 0.82 8.9 13.9 1.6 7.9 13.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) MctB PF11382.8 KEG07410.1 - 0.84 9.3 2.8 1.3 8.7 2.8 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF4407 PF14362.6 KEG07410.1 - 4.2 6.6 7.5 6 6.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KEG07410.1 - 4.3 7.6 8.2 1.6 9.0 5.1 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 KEG07410.1 - 5.3 7.2 8.4 0.91 9.7 2.5 2.4 2 0 0 2 2 2 0 Basic region leucine zipper FliD_N PF02465.18 KEG07410.1 - 6.3 7.6 9.6 0.77 10.5 2.7 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TssO PF17561.2 KEG07410.1 - 8 6.6 9.3 14 5.8 9.3 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO Exo_endo_phos_2 PF14529.6 KEG07412.1 - 3e-10 40.0 0.0 3.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase YLP PF02757.17 KEG07412.1 - 0.19 11.8 0.7 0.36 10.9 0.7 1.5 1 0 0 1 1 1 0 YLP motif RVT_1 PF00078.27 KEG07413.1 - 0.00033 20.2 0.1 0.00047 19.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KEG07414.1 - 5.6e-18 65.3 0.1 7.4e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VanW PF04294.13 KEG07414.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 VanW like protein RVT_1 PF00078.27 KEG07415.1 - 2.6e-09 36.9 0.0 4.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-Di19 PF05605.12 KEG07416.1 - 0.58 10.5 4.4 0.65 10.3 1.5 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PheRS_DBD1 PF18552.1 KEG07417.1 - 0.008 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 PheRS DNA binding domain 1 Pex24p PF06398.11 KEG07418.1 - 2e-06 27.0 0.1 2.3e-06 26.9 0.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pex14_N PF04695.13 KEG07418.1 - 0.24 12.1 5.1 0.32 11.7 5.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KEG07418.1 - 9.1 5.8 12.3 10 5.7 12.3 1.1 1 0 0 1 1 1 0 Spt20 family SH3BGR PF04908.15 KEG07419.1 - 2.6e-10 40.3 0.3 1.5e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KEG07419.1 - 0.0003 21.0 0.0 0.00088 19.4 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin SOG2 PF10428.9 KEG07419.1 - 0.98 8.5 12.1 1.2 8.3 12.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TAL_FSA PF00923.19 KEG07420.1 - 2.9e-10 40.0 0.0 3.3e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Peptidase_M8 PF01457.16 KEG07421.1 - 1.3e-124 416.8 4.9 2.2e-124 416.1 4.9 1.3 1 1 0 1 1 1 1 Leishmanolysin Bunya_RdRp PF04196.12 KEG07422.1 - 0.056 11.8 2.4 0.076 11.4 2.4 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Mucin PF01456.17 KEG07422.1 - 0.085 12.8 29.5 1.1 9.3 10.1 2.9 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF3138 PF11336.8 KEG07422.1 - 0.24 9.9 1.4 0.38 9.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PI-PLC-X PF00388.19 KEG07424.1 - 0.072 12.7 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Amastin PF07344.11 KEG07425.1 - 1.8e-08 34.4 9.9 2.6e-08 33.9 9.9 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Colicin_V PF02674.16 KEG07425.1 - 0.012 15.6 5.4 0.012 15.6 5.4 2.0 2 0 0 2 2 2 0 Colicin V production protein FA_desaturase PF00487.24 KEG07425.1 - 0.48 10.2 2.7 0.26 11.1 0.5 1.6 1 1 1 2 2 2 0 Fatty acid desaturase DUF4231 PF14015.6 KEG07425.1 - 0.79 10.2 4.6 4 8.0 3.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Tetraspanin PF00335.20 KEG07425.1 - 3.8 7.2 11.6 0.46 10.2 0.1 2.7 2 2 0 2 2 2 0 Tetraspanin family Adaptin_binding PF10199.9 KEG07426.1 - 0.34 11.5 3.4 7.5 7.2 3.0 2.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Exonuc_VII_L PF02601.15 KEG07426.1 - 7.6 6.0 14.6 0.42 10.1 3.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit EphA2_TM PF14575.6 KEG07430.1 - 0.0024 18.7 0.0 0.0031 18.4 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 KEG07430.1 - 0.017 15.7 3.9 0.017 15.7 3.9 1.9 1 1 1 2 2 2 0 Small Novel Rich in Cartilage S1FA PF04689.13 KEG07430.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF202 PF02656.15 KEG07430.1 - 0.031 14.7 0.1 0.051 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Sensor PF13796.6 KEG07430.1 - 0.036 14.1 0.3 0.065 13.3 0.3 1.4 1 0 0 1 1 1 0 Putative sensor ECSCR PF15820.5 KEG07430.1 - 0.053 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator VSP PF03302.13 KEG07430.1 - 0.069 12.0 0.9 0.11 11.3 0.1 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein CD34_antigen PF06365.12 KEG07430.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family FixQ PF05545.11 KEG07430.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LAX PF15681.5 KEG07430.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X Amnionless PF14828.6 KEG07430.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KEG07430.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4381 PF14316.6 KEG07430.1 - 0.2 11.9 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FeoB_associated PF12669.7 KEG07430.1 - 0.62 10.5 5.1 2.2 8.8 5.1 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DNA_pol_A_exo1 PF01612.20 KEG07432.1 - 1.5e-10 41.0 0.0 2.2e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.20 KEG07433.1 - 1.8e-27 93.5 44.1 8.8e-06 25.3 1.3 7.6 7 0 0 7 7 7 7 MORN repeat Kinesin PF00225.23 KEG07433.1 - 4.5e-20 71.9 0.0 4.1e-19 68.7 0.0 2.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG07433.1 - 4.8e-05 23.3 0.0 0.00013 21.9 0.0 1.8 1 1 0 1 1 1 1 Microtubule binding DUF3048_C PF17479.2 KEG07433.1 - 0.041 14.3 6.2 0.26 11.7 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain T6PP_N PF18572.1 KEG07433.1 - 1.2 9.0 9.1 0.11 12.4 2.4 2.6 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Bap31 PF05529.12 KEG07434.1 - 0.0058 16.5 2.3 0.01 15.7 2.3 1.5 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region MTABC_N PF16185.5 KEG07434.1 - 0.15 11.5 2.2 0.097 12.2 0.7 1.4 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DSBA PF01323.20 KEG07435.1 - 0.049 13.4 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain ROF PF07073.12 KEG07435.1 - 0.078 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) Proteasome PF00227.26 KEG07436.1 - 1.8e-49 167.8 0.0 2.4e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG07436.1 - 1.1e-12 47.3 0.3 1.9e-12 46.6 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Usher PF00577.20 KEG07436.1 - 0.031 13.2 0.3 0.04 12.8 0.3 1.2 1 0 0 1 1 1 0 Outer membrane usher protein U1snRNP70_N PF12220.8 KEG07436.1 - 0.13 12.9 2.0 0.28 11.8 2.0 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AA_permease_2 PF13520.6 KEG07437.1 - 5.1e-34 117.8 38.1 6.6e-34 117.5 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEG07437.1 - 4.6e-09 35.4 33.0 1.2e-08 34.0 32.9 1.6 1 1 0 1 1 1 1 Amino acid permease DUF3767 PF12597.8 KEG07437.1 - 0.034 14.0 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Senescence_reg PF04520.13 KEG07438.1 - 2 9.2 7.4 0.12 13.3 1.8 1.7 2 0 0 2 2 2 0 Senescence regulator Galactosyl_T PF01762.21 KEG07439.1 - 0.031 14.1 0.2 0.27 11.0 0.0 2.5 2 1 1 3 3 3 0 Galactosyltransferase SUIM_assoc PF16619.5 KEG07440.1 - 0.00022 21.2 0.0 0.011 15.7 0.0 3.3 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 SET PF00856.28 KEG07441.1 - 2e-11 44.5 0.0 9.9e-08 32.5 0.0 2.8 2 1 1 3 3 3 2 SET domain UBA PF00627.31 KEG07441.1 - 0.045 13.7 0.3 2 8.4 0.1 2.4 2 0 0 2 2 2 0 UBA/TS-N domain SAF PF08666.12 KEG07441.1 - 0.058 14.0 0.0 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 SAF domain DUF948 PF06103.11 KEG07443.1 - 0.82 10.0 3.8 23 5.3 0.2 4.3 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Streptin-Immun PF11083.8 KEG07443.1 - 1.3 9.5 17.4 0.81 10.1 0.4 4.3 4 1 1 5 5 5 0 Lantibiotic streptin immunity protein Fib_alpha PF08702.10 KEG07443.1 - 1.3 9.2 12.9 0.62 10.2 0.6 3.5 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TSC22 PF01166.18 KEG07443.1 - 1.3 9.3 12.8 0.14 12.5 1.7 4.4 4 1 1 5 5 5 0 TSC-22/dip/bun family Mgr1 PF08602.10 KEG07443.1 - 4.9 5.9 8.5 3 6.6 0.4 2.2 1 1 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit RBD-FIP PF09457.10 KEG07443.1 - 7.7 6.5 12.2 28 4.7 3.1 4.7 3 0 0 3 3 3 0 FIP domain ATG16 PF08614.11 KEG07445.1 - 0.00093 19.5 52.2 0.13 12.4 1.3 5.2 3 1 2 5 5 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KEG07445.1 - 0.0012 17.8 39.7 0.04 12.8 18.8 4.5 4 0 0 4 4 4 3 Spc7 kinetochore protein Filament PF00038.21 KEG07445.1 - 0.0018 17.9 21.4 0.0018 17.9 21.4 4.1 4 0 0 4 4 4 1 Intermediate filament protein KASH_CCD PF14662.6 KEG07445.1 - 0.012 15.4 11.0 0.012 15.4 11.0 4.8 4 1 1 5 5 5 0 Coiled-coil region of CCDC155 or KASH RasGAP_C PF03836.15 KEG07445.1 - 0.015 15.4 12.2 0.015 15.4 12.2 4.5 4 1 1 5 5 5 0 RasGAP C-terminus Peptidase_S28 PF05577.12 KEG07445.1 - 0.11 11.3 6.1 0.19 10.5 6.1 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 YabA PF06156.13 KEG07445.1 - 0.13 12.9 30.2 0.7 10.6 2.7 5.3 4 1 1 5 5 5 0 Initiation control protein YabA Lipase_GDSL PF00657.22 KEG07445.1 - 0.3 11.0 4.9 2.2 8.2 4.3 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase CENP-F_leu_zip PF10473.9 KEG07445.1 - 0.36 10.9 49.6 0.31 11.0 5.9 5.7 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 KEG07445.1 - 0.72 9.6 46.2 0.13 11.9 14.9 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4201) Taxilin PF09728.9 KEG07445.1 - 1.9 7.6 36.6 0.038 13.2 18.8 3.5 4 0 0 4 4 4 0 Myosin-like coiled-coil protein CALCOCO1 PF07888.11 KEG07445.1 - 3 6.6 47.4 0.023 13.6 20.5 3.6 4 0 0 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like TIP120 PF08623.10 KEG07445.1 - 5.8 6.6 9.7 0.11 12.3 1.9 2.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) USP8_interact PF08941.10 KEG07445.1 - 7.4 6.3 24.1 0.23 11.2 0.6 4.8 5 0 0 5 5 5 0 USP8 interacting Seryl_tRNA_N PF02403.22 KEG07445.1 - 7.5 6.8 38.3 1.7 8.9 1.5 5.7 4 2 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF4686 PF15742.5 KEG07445.1 - 8.7 5.4 47.3 0.014 14.5 23.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4686) Arm-DNA-bind_3 PF13356.6 KEG07447.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain DUF1180 PF06679.12 KEG07447.1 - 3.2 8.1 5.6 4.3 7.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GlcNAc PF11397.8 KEG07448.1 - 3.1e-127 424.9 0.0 4.2e-127 424.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF3963 PF13124.6 KEG07448.1 - 0.0081 16.1 2.4 0.019 14.9 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) SUR7 PF06687.12 KEG07449.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF523 PF04463.12 KEG07451.1 - 1.6e-06 28.2 0.0 7.9e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.15 KEG07452.1 - 0.00027 20.5 1.8 0.00037 20.1 1.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.22 KEG07453.1 - 2.2e-73 246.1 1.0 4e-73 245.2 1.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KEG07453.1 - 1.6e-26 92.8 0.2 1.6e-26 92.8 0.2 3.8 2 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 KEG07453.1 - 3.5e-14 52.8 1.5 9.8e-14 51.3 1.5 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_17 PF13207.6 KEG07453.1 - 2.3e-05 24.8 0.3 6.1e-05 23.5 0.3 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KEG07453.1 - 0.00011 21.8 0.8 0.00047 19.8 0.8 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEG07453.1 - 0.00047 20.3 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KEG07453.1 - 0.0019 17.2 1.2 0.031 13.3 0.2 2.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KEG07453.1 - 0.0029 17.7 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KEG07453.1 - 0.0031 17.3 0.2 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEG07453.1 - 0.0056 17.0 0.3 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG07453.1 - 0.011 16.1 0.1 0.034 14.5 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain APS_kinase PF01583.20 KEG07453.1 - 0.021 14.7 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 KEG07453.1 - 0.025 14.4 2.3 0.54 10.0 0.1 2.8 2 1 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 KEG07453.1 - 0.026 14.4 1.0 4.5 7.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain MobB PF03205.14 KEG07453.1 - 0.028 14.3 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KEG07453.1 - 0.031 14.0 0.2 0.076 12.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KEG07453.1 - 0.032 14.0 0.9 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KEG07453.1 - 0.032 13.5 0.0 0.083 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KEG07453.1 - 0.032 14.7 2.1 3.6 8.1 0.0 3.0 3 0 0 3 3 3 0 ABC transporter Methyltransf_24 PF13578.6 KEG07453.1 - 0.039 15.0 0.0 0.11 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SRPRB PF09439.10 KEG07453.1 - 0.042 13.3 0.5 7.3 6.0 0.1 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_8 PF12780.7 KEG07453.1 - 0.08 12.3 2.5 8.5 5.6 0.1 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 DUF4788 PF16032.5 KEG07453.1 - 0.084 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) NTPase_1 PF03266.15 KEG07453.1 - 0.12 12.3 6.7 0.52 10.2 3.3 2.6 2 1 0 2 2 2 0 NTPase AAA PF00004.29 KEG07453.1 - 0.13 12.7 1.4 0.67 10.4 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KEG07453.1 - 0.17 12.0 0.8 1.2 9.2 0.8 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEG07453.1 - 0.3 11.1 1.5 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Dynamin family Pkinase PF00069.25 KEG07455.1 - 6.5e-48 163.4 0.0 2.7e-36 125.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07455.1 - 2.2e-21 76.3 0.0 1.3e-19 70.5 0.0 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG07455.1 - 0.00013 21.4 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG07455.1 - 0.07 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEG07455.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GAGA_bind PF06217.12 KEG07456.1 - 0.074 13.3 0.5 0.11 12.7 0.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FAM184 PF15665.5 KEG07457.1 - 8.3e-05 22.5 1.0 8.3e-05 22.5 1.0 4.5 2 1 1 4 4 4 1 Family with sequence similarity 184, A and B Prominin PF05478.11 KEG07457.1 - 0.2 9.6 23.3 0.054 11.4 3.6 3.4 1 1 2 3 3 3 0 Prominin ApoLp-III PF07464.11 KEG07457.1 - 0.41 10.7 22.3 0.32 11.1 0.2 4.9 2 1 1 5 5 5 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KEG07457.1 - 0.86 9.6 20.8 0.24 11.5 0.5 5.2 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KEG07457.1 - 1.8 8.4 50.5 2.1 8.2 16.8 4.2 2 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain Octopine_DH PF02317.17 KEG07457.1 - 2.8 8.0 4.5 4.5 7.4 0.1 3.2 2 2 2 4 4 4 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Fib_alpha PF08702.10 KEG07457.1 - 7.5 6.7 25.2 1.1 9.4 3.8 5.3 1 1 6 7 7 7 0 Fibrinogen alpha/beta chain family Utp13 PF08625.11 KEG07458.1 - 2.2e-36 124.9 3.7 4.1e-36 124.0 3.7 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KEG07458.1 - 3.5e-35 119.4 13.9 4.6e-07 30.4 0.1 9.8 9 1 1 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG07458.1 - 3.1e-16 59.4 2.4 8.3e-08 32.4 0.0 5.8 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG07458.1 - 1e-05 24.7 0.8 1.1 8.2 0.0 4.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein UTP15_C PF09384.10 KEG07458.1 - 1.7e-05 24.5 2.2 3.3e-05 23.6 2.2 1.4 1 0 0 1 1 1 1 UTP15 C terminal Utp12 PF04003.12 KEG07458.1 - 2.1e-05 24.8 1.7 3.9e-05 23.9 1.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KEG07458.1 - 0.015 14.0 7.0 0.15 10.7 0.4 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEG07458.1 - 0.025 13.3 0.0 1.8 7.3 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KEG07458.1 - 0.033 12.7 0.3 2.1 6.8 0.0 3.2 3 1 1 4 4 4 0 Cytochrome D1 heme domain tRNA-synt_1e PF01406.19 KEG07459.1 - 4.9e-110 367.6 0.0 6.9e-110 367.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KEG07459.1 - 0.00033 19.1 0.1 0.016 13.5 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEG07459.1 - 0.00062 18.6 0.2 0.013 14.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (M) DALR_2 PF09190.11 KEG07459.1 - 0.12 12.9 0.1 0.8 10.2 0.0 2.4 3 0 0 3 3 3 0 DALR domain Peptidase_C14 PF00656.22 KEG07460.1 - 9e-58 196.1 0.1 1.2e-57 195.7 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KEG07460.1 - 0.011 15.7 0.0 0.56 10.2 0.0 2.5 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain AAA_16 PF13191.6 KEG07461.1 - 0.08 13.3 0.4 0.65 10.4 0.1 2.4 3 0 0 3 3 3 0 AAA ATPase domain LAM_C PF12544.8 KEG07461.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Pro_isomerase PF00160.21 KEG07463.1 - 1.8e-38 132.3 0.0 2.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Viral_P18 PF04521.13 KEG07463.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein EF-hand_8 PF13833.6 KEG07464.1 - 7.1e-08 32.2 0.1 4.7e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KEG07464.1 - 0.00015 22.1 0.7 0.023 15.1 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG07464.1 - 0.00026 20.7 0.0 0.028 14.3 0.0 3.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KEG07464.1 - 0.057 13.0 0.1 0.87 9.3 0.0 2.5 2 0 0 2 2 2 0 EF hand TPR_12 PF13424.6 KEG07465.1 - 0.0043 17.3 0.5 0.13 12.6 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG07465.1 - 0.0083 16.6 0.4 0.76 10.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG07465.1 - 0.039 14.1 0.7 0.92 9.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PDEase_I_N PF08499.12 KEG07465.1 - 0.078 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal TPR_4 PF07721.14 KEG07465.1 - 0.1 13.3 0.1 3 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MAM33 PF02330.16 KEG07466.1 - 5.5e-18 65.7 1.7 9.3e-16 58.4 1.7 2.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein MYCBPAP PF14646.6 KEG07467.1 - 1.6e-12 47.2 0.0 1.3e-07 30.9 0.0 2.5 2 1 0 2 2 2 2 MYCBP-associated protein family Kinesin PF00225.23 KEG07468.1 - 2.9e-87 292.7 0.0 5e-87 291.9 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG07468.1 - 9e-16 58.1 0.0 2.3e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding GIT1_C PF12205.8 KEG07468.1 - 0.07 13.2 1.1 0.24 11.5 1.1 1.9 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF87 PF01935.17 KEG07468.1 - 6.8 6.7 6.2 8.9 6.3 0.7 3.0 2 1 1 3 3 3 0 Helicase HerA, central domain APG6_N PF17675.1 KEG07469.1 - 0.19 12.3 36.2 0.29 11.7 17.1 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region TraG_N PF07916.11 KEG07469.1 - 4.9 5.9 4.9 6 5.6 4.9 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Vps16_C PF04840.12 KEG07470.1 - 2.4e-26 92.5 0.0 4.7e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 KEG07470.1 - 5.3e-26 91.3 0.0 5.4e-19 68.2 0.0 2.6 2 1 0 2 2 2 2 Vps16, N-terminal region FliJ PF02050.16 KEG07471.1 - 0.012 15.9 8.9 0.27 11.5 5.0 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein ANAPC4 PF12896.7 KEG07471.1 - 0.023 14.2 1.2 1.8 8.0 0.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF948 PF06103.11 KEG07471.1 - 0.062 13.6 13.0 0.82 10.0 0.3 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.9 KEG07471.1 - 0.14 11.8 11.4 0.13 11.9 3.5 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein LXG PF04740.12 KEG07471.1 - 0.29 10.8 7.6 0.9 9.2 7.0 1.9 1 1 0 1 1 1 0 LXG domain of WXG superfamily Syntaxin_2 PF14523.6 KEG07471.1 - 0.58 10.6 8.0 9.4 6.7 3.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF4810 PF16068.5 KEG07471.1 - 0.81 10.3 0.1 0.81 10.3 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) SNARE PF05739.19 KEG07471.1 - 1.4 9.0 4.4 14 5.8 0.3 2.7 2 0 0 2 2 2 0 SNARE domain AATF-Che1 PF13339.6 KEG07471.1 - 1.8 9.2 11.4 2.8 8.6 3.3 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor TPR_MLP1_2 PF07926.12 KEG07471.1 - 2.2 8.4 14.4 0.82 9.7 6.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 KEG07471.1 - 2.5 5.9 5.7 5.4 4.8 5.7 1.6 1 1 0 1 1 1 0 Prominin SKA2 PF16740.5 KEG07471.1 - 3.8 7.3 8.5 0.49 10.2 2.1 2.6 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Baculo_PEP_C PF04513.12 KEG07471.1 - 6.5 6.8 8.7 2.2 8.3 3.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alanine_zipper PF11839.8 KEG07471.1 - 9.8 6.6 12.5 21 5.6 1.7 3.5 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Mucin PF01456.17 KEG07473.1 - 0.75 9.8 13.5 0.66 10.0 13.1 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein T6PP_N PF18572.1 KEG07474.1 - 0.008 16.0 2.0 0.013 15.3 0.1 2.2 2 0 0 2 2 2 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF4461 PF14688.6 KEG07474.1 - 0.073 12.9 0.8 0.33 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) DUF948 PF06103.11 KEG07475.1 - 0.012 15.8 9.6 0.39 11.0 1.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Alanine_zipper PF11839.8 KEG07475.1 - 0.38 11.1 78.1 0.03 14.7 13.8 5.9 5 1 0 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein VasI PF11319.8 KEG07475.1 - 0.9 9.2 3.9 0.64 9.7 0.1 2.5 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 DUF3818 PF12825.7 KEG07475.1 - 3 6.8 6.2 4.4 6.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Tape_meas_lam_C PF09718.10 KEG07475.1 - 6.6 6.9 11.4 1.3 9.2 2.1 3.8 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RBB1NT PF08169.11 KEG07476.1 - 0.1 12.8 0.0 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 RBB1NT (NUC162) domain Pro_isomerase PF00160.21 KEG07477.1 - 1.1e-12 48.5 0.0 1.5e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Nuc_deoxyrib_tr PF05014.15 KEG07478.1 - 1.3e-37 128.8 0.0 1.5e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.6 KEG07478.1 - 0.045 14.2 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) Nuc_deoxyri_tr3 PF11071.8 KEG07478.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ DUF4719 PF15843.5 KEG07482.1 - 0.17 12.0 5.4 1.5 8.9 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DASH_Dad3 PF08656.10 KEG07482.1 - 7.7 6.7 11.0 1.6 8.9 1.4 3.8 3 0 0 3 3 3 0 DASH complex subunit Dad3 VSP PF03302.13 KEG07484.1 - 0.043 12.7 3.5 0.08 11.8 3.5 1.5 1 0 0 1 1 1 0 Giardia variant-specific surface protein RBB1NT PF08169.11 KEG07484.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Peptidase_C58 PF03543.14 KEG07488.1 - 0.096 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen RsbU_N PF08673.10 KEG07490.1 - 0.0021 18.1 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoserine phosphatase RsbU, N-terminal domain Ribosomal_S7 PF00177.21 KEG07491.1 - 2.6e-34 118.0 0.9 3.2e-34 117.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RNA_pol_3_Rpc31 PF11705.8 KEG07492.1 - 0.0024 18.2 3.3 0.0031 17.8 3.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 zf-C2H2_10 PF16588.5 KEG07493.1 - 0.018 14.7 2.4 0.021 14.6 0.5 2.0 2 0 0 2 2 2 0 C2H2 zinc-finger PDZ_2 PF13180.6 KEG07493.1 - 0.033 14.5 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PriA_C PF18074.1 KEG07493.1 - 0.039 14.8 0.7 5.6 7.9 0.3 2.6 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Glyco_hydro_66 PF13199.6 KEG07493.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 LuxQ-periplasm PF09308.10 KEG07493.1 - 0.14 11.6 0.1 0.32 10.4 0.0 1.6 1 1 1 2 2 2 0 LuxQ, periplasmic FAD_binding_1 PF00667.20 KEG07493.1 - 0.43 10.1 1.9 0.51 9.9 0.7 1.7 2 0 0 2 2 2 0 FAD binding domain Torus PF16131.5 KEG07494.1 - 1.3e-05 25.9 0.2 0.34 11.6 0.1 2.6 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KEG07494.1 - 0.0035 17.2 16.1 0.23 11.4 2.9 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG07494.1 - 0.0037 17.3 17.7 0.095 12.8 6.5 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KEG07494.1 - 0.029 14.2 14.2 0.039 13.8 2.9 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger YobH PF13996.6 KEG07494.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 YobH-like protein TetR_C_14 PF17754.1 KEG07497.1 - 0.027 14.4 2.2 0.18 11.8 1.3 2.7 2 0 0 2 2 2 0 MftR C-terminal domain Adeno_PIX PF03955.14 KEG07498.1 - 1.1 9.5 9.2 0.097 12.8 1.5 2.6 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) RRM_1 PF00076.22 KEG07499.1 - 7.1e-83 272.4 7.8 1e-24 86.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEG07499.1 - 1.2e-08 35.0 0.6 0.25 11.4 0.2 4.3 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 KEG07499.1 - 6.9e-08 32.1 0.1 0.0094 15.5 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KEG07499.1 - 2.5e-06 27.4 0.0 0.012 15.4 0.0 3.3 3 1 1 4 4 4 2 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 KEG07499.1 - 2.8e-05 24.0 0.6 2.2 8.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEG07499.1 - 5.6e-05 23.2 0.3 5.1 7.3 0.0 4.7 4 2 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 KEG07499.1 - 9.5e-05 22.2 0.0 4.7 7.1 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KEG07499.1 - 0.0024 18.2 0.0 1.2 9.3 0.0 3.5 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 KEG07499.1 - 0.0026 17.4 1.1 9.7 5.9 0.0 3.8 3 1 0 3 3 3 2 Histone lysine methyltransferase SET associated OB_RNB PF08206.11 KEG07499.1 - 0.023 14.4 0.2 3.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain Pkinase_C PF00433.24 KEG07499.1 - 0.05 14.3 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain XS PF03468.14 KEG07499.1 - 0.1 12.9 0.6 7.7 6.9 0.0 3.4 4 0 0 4 4 4 0 XS domain Peptidase_C48 PF02902.19 KEG07500.1 - 4.9e-05 23.3 0.0 6.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NB PF04159.13 KEG07500.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 NB glycoprotein SesA PF17107.5 KEG07502.1 - 0.69 10.1 3.2 1.1 9.5 1.2 2.4 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-Tim10_DDP PF02953.15 KEG07503.1 - 1e-10 41.1 3.5 1.1e-10 41.0 3.5 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TRAP_alpha PF03896.16 KEG07504.1 - 1.9e-22 79.8 0.0 2.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit GRP PF07172.11 KEG07504.1 - 0.088 13.5 0.7 0.16 12.7 0.0 1.7 2 0 0 2 2 2 0 Glycine rich protein family UVR PF02151.19 KEG07509.1 - 1.9e-05 24.2 13.2 6.9e-05 22.5 0.3 3.5 3 0 0 3 3 3 2 UvrB/uvrC motif HEAT PF02985.22 KEG07509.1 - 0.0032 17.6 4.3 0.47 10.9 0.5 3.9 3 0 0 3 3 3 2 HEAT repeat Exostosin PF03016.15 KEG07511.1 - 6.3e-38 130.7 0.3 9.1e-38 130.2 0.3 1.3 1 0 0 1 1 1 1 Exostosin family Ufm1 PF03671.14 KEG07514.1 - 4.9e-35 119.5 0.1 5.7e-35 119.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Stealth_CR2 PF11380.8 KEG07515.1 - 1.5e-16 60.5 0.6 1.8e-14 53.8 0.6 2.7 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KEG07515.1 - 9.2e-10 38.3 0.9 2.3e-09 37.0 0.9 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KEG07515.1 - 0.076 12.9 1.4 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 ubiquitin PF00240.23 KEG07516.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CysG_dimeriser PF10414.9 KEG07516.1 - 0.043 13.5 0.4 0.16 11.7 0.4 1.9 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Roughex PF06020.11 KEG07516.1 - 0.14 11.2 5.8 0.036 13.2 2.7 1.6 2 0 0 2 2 2 0 Drosophila roughex protein UAA PF08449.11 KEG07517.1 - 4.9e-07 29.2 16.2 7.1e-07 28.7 16.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEG07517.1 - 8.4e-07 29.2 23.3 9e-05 22.7 4.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KEG07517.1 - 0.0012 18.2 11.9 0.002 17.6 11.9 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family SecA_DEAD PF07517.14 KEG07517.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Kinesin PF00225.23 KEG07518.1 - 6e-35 120.7 0.0 6.4e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG07518.1 - 1.1e-24 87.0 0.0 1.6e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding TPR_1 PF00515.28 KEG07519.1 - 3.9e-13 48.6 5.7 1e-07 31.5 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG07519.1 - 6.5e-09 35.2 12.8 7.5e-06 25.7 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG07519.1 - 1e-08 34.7 2.5 0.00025 20.7 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KEG07519.1 - 0.00061 19.8 7.6 0.0095 16.1 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 KEG07519.1 - 0.0032 17.5 1.4 0.081 13.0 0.1 2.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KEG07519.1 - 0.012 15.6 10.9 0.054 13.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG07519.1 - 0.013 16.3 3.4 1.4 9.9 0.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEG07519.1 - 0.025 14.6 3.6 0.054 13.5 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG07519.1 - 0.051 14.2 15.6 0.31 11.7 1.4 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG07519.1 - 0.06 13.4 0.2 0.06 13.4 0.2 2.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KEG07519.1 - 0.081 13.4 7.6 0.09 13.3 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG07519.1 - 0.086 13.5 0.3 0.086 13.5 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG07519.1 - 0.55 10.4 5.2 0.42 10.8 1.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG07519.1 - 1.2 9.5 16.1 0.99 9.7 0.1 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ARPC4 PF05856.12 KEG07520.1 - 3.8e-68 228.3 0.3 4.2e-68 228.2 0.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.32 KEG07521.1 - 0.015 16.1 5.9 1.7 9.7 1.2 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Aldedh PF00171.22 KEG07522.1 - 0.0022 16.6 2.8 1.4 7.3 0.1 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family DUF2754 PF10953.8 KEG07527.1 - 0.023 14.9 0.6 0.041 14.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) ABC_tran PF00005.27 KEG07529.1 - 2.5e-17 63.6 0.0 5.9e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG07529.1 - 0.00027 20.8 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEG07529.1 - 0.00044 19.9 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KEG07529.1 - 0.00093 18.7 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEG07529.1 - 0.0056 17.2 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG07529.1 - 0.0077 16.5 0.6 0.12 12.7 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KEG07529.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 KEG07529.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KEG07529.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain G-alpha PF00503.20 KEG07529.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit HCV_capsid PF01543.17 KEG07529.1 - 0.2 11.9 0.4 0.48 10.6 0.4 1.6 1 0 0 1 1 1 0 Hepatitis C virus capsid protein ZapB PF06005.12 KEG07531.1 - 0.0019 18.6 9.2 0.0019 18.6 9.2 1.7 2 0 0 2 2 2 1 Cell division protein ZapB DUF3584 PF12128.8 KEG07531.1 - 0.015 12.9 4.6 0.019 12.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KEG07531.1 - 0.021 13.7 5.8 0.03 13.2 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tektin PF03148.14 KEG07531.1 - 0.034 12.9 8.0 0.045 12.5 8.0 1.1 1 0 0 1 1 1 0 Tektin family Sec8_exocyst PF04048.14 KEG07531.1 - 0.055 13.4 2.6 0.1 12.5 2.6 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.10 KEG07531.1 - 0.08 13.1 3.9 0.12 12.6 3.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EMC3_TMCO1 PF01956.16 KEG07531.1 - 0.11 12.2 0.1 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Baculo_F PF12259.8 KEG07531.1 - 0.17 10.4 1.4 0.2 10.1 1.4 1.0 1 0 0 1 1 1 0 Baculovirus F protein TMPIT PF07851.13 KEG07531.1 - 0.2 10.8 2.9 0.28 10.4 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Tho2 PF11262.8 KEG07531.1 - 0.23 10.6 2.6 0.3 10.3 2.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HAUS6_N PF14661.6 KEG07531.1 - 0.23 11.0 5.5 0.32 10.5 5.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SlyX PF04102.12 KEG07531.1 - 0.23 12.1 9.6 0.76 10.4 5.7 3.4 2 0 0 2 2 2 0 SlyX AAA_23 PF13476.6 KEG07531.1 - 0.27 11.7 2.6 0.37 11.3 2.6 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 KEG07531.1 - 0.28 9.1 3.3 0.33 8.8 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_Packaging PF11053.8 KEG07531.1 - 0.33 10.8 3.8 0.67 9.8 1.1 2.2 1 1 1 2 2 2 0 Terminase DNA packaging enzyme Exonuc_VII_L PF02601.15 KEG07531.1 - 0.81 9.2 5.3 1.2 8.6 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KEG07531.1 - 0.94 8.3 3.5 1.1 8.0 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein OmpH PF03938.14 KEG07531.1 - 1.4 9.3 10.5 2.2 8.6 10.5 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DMPK_coil PF08826.10 KEG07531.1 - 2.9 8.1 12.0 1.1 9.4 5.7 2.3 1 1 0 2 2 2 0 DMPK coiled coil domain like WD40 PF00400.32 KEG07532.1 - 1.9e-11 44.3 4.8 1e-05 26.2 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.6 KEG07532.1 - 0.00045 19.9 2.0 0.00045 19.9 2.0 2.0 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KEG07532.1 - 0.0072 16.6 0.0 2.8 8.3 0.0 3.5 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KEG07532.1 - 0.17 12.4 4.0 14 6.3 0.1 4.4 4 0 0 4 4 4 0 PQQ-like domain Galactosyl_T PF01762.21 KEG07536.1 - 4.2e-09 36.5 0.0 0.00048 20.0 0.0 3.6 3 1 0 3 3 3 2 Galactosyltransferase Aa_trans PF01490.18 KEG07537.1 - 2.4e-52 178.0 32.4 3.1e-52 177.7 32.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG07537.1 - 0.00011 21.5 28.6 0.00036 19.7 27.9 2.3 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Pribosyltran_N PF13793.6 KEG07539.1 - 3.7e-44 149.4 0.4 7.7e-27 93.6 0.1 2.7 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEG07539.1 - 1.4e-23 83.9 1.2 5.2e-23 82.0 0.3 2.2 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEG07539.1 - 2e-16 59.9 0.2 3.9e-16 59.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEG07539.1 - 0.048 13.1 0.1 0.081 12.4 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase zn-ribbon_14 PF16503.5 KEG07539.1 - 0.16 11.5 0.7 0.5 9.9 0.7 1.8 1 0 0 1 1 1 0 Zinc-ribbon PRORP PF16953.5 KEG07541.1 - 6.7e-27 94.5 0.0 5.7e-23 81.7 0.1 2.4 2 0 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 KEG07541.1 - 2e-10 40.4 0.2 3e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Xpo1 PF08389.12 KEG07542.1 - 2.6e-20 73.0 0.0 3.5e-19 69.3 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 KEG07542.1 - 0.029 14.6 0.5 11 6.6 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat F-box_4 PF15966.5 KEG07542.1 - 0.39 10.6 1.7 14 5.6 0.3 2.8 2 0 0 2 2 2 0 F-box PI3_PI4_kinase PF00454.27 KEG07543.1 - 1.9e-49 168.7 0.0 3e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KEG07543.1 - 1.6e-07 31.0 0.1 3.6e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 FATC domain Fucokinase PF07959.12 KEG07545.1 - 2.4e-29 102.5 0.0 1.4e-27 96.7 0.0 2.1 1 1 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 KEG07545.1 - 7.2e-07 29.5 0.0 2.2e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KEG07545.1 - 8.7e-06 25.9 0.7 3.2e-05 24.1 0.4 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain MMR_HSR1 PF01926.23 KEG07547.1 - 9.3e-13 48.3 0.0 1.9e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEG07547.1 - 5e-06 26.7 0.1 0.00011 22.2 0.1 2.4 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KEG07547.1 - 9.7e-06 25.6 0.0 0.00051 20.0 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KEG07547.1 - 0.0028 17.4 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 KEG07547.1 - 0.0067 16.0 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 KEG07547.1 - 0.015 15.8 0.1 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 KEG07547.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IIGP PF05049.13 KEG07547.1 - 0.14 11.2 0.0 0.63 9.0 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Alginate_lyase2 PF08787.11 KEG07547.1 - 0.15 11.9 0.2 0.39 10.5 0.2 1.6 1 0 0 1 1 1 0 Alginate lyase DUF1738 PF08401.11 KEG07548.1 - 7.8e-05 22.8 0.0 0.00063 19.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) DUF1738 PF08401.11 KEG07549.1 - 0.0058 16.7 0.2 0.16 12.0 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1738) AAA PF00004.29 KEG07550.1 - 1.2e-51 174.6 0.0 5.7e-40 136.8 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG07550.1 - 4e-09 36.1 3.4 9.5e-08 31.7 1.3 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KEG07550.1 - 2.4e-08 34.6 0.1 0.08 13.3 0.1 4.1 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KEG07550.1 - 4.7e-06 26.9 0.0 0.11 12.8 0.0 3.4 3 1 1 4 4 4 2 AAA domain AAA_5 PF07728.14 KEG07550.1 - 1.1e-05 25.4 0.0 0.03 14.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG07550.1 - 9.7e-05 22.2 0.0 0.00063 19.5 0.0 2.4 3 0 0 3 3 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KEG07550.1 - 0.00049 19.9 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KEG07550.1 - 0.00069 19.2 0.0 0.78 9.2 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region TIP49 PF06068.13 KEG07550.1 - 0.0013 18.0 0.0 0.0037 16.5 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 KEG07550.1 - 0.0014 18.6 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KEG07550.1 - 0.0014 18.9 0.0 0.38 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KEG07550.1 - 0.0018 18.4 0.0 0.49 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 KEG07550.1 - 0.0024 17.8 0.0 0.0084 16.1 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KEG07550.1 - 0.0024 17.3 0.0 0.076 12.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KEG07550.1 - 0.0038 16.4 0.0 3.4 6.8 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.14 KEG07550.1 - 0.0072 16.5 0.0 0.11 12.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) MCM PF00493.23 KEG07550.1 - 0.0099 15.0 0.0 1.2 8.1 0.0 2.9 3 0 0 3 3 3 1 MCM P-loop domain ABC_tran PF00005.27 KEG07550.1 - 0.011 16.2 0.0 1.7 9.2 0.0 2.9 3 0 0 3 3 2 0 ABC transporter Molydop_binding PF01568.21 KEG07550.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Rad17 PF03215.15 KEG07550.1 - 0.017 15.0 0.0 0.091 12.7 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KEG07550.1 - 0.017 14.7 0.2 3.3 7.2 0.0 3.1 3 1 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KEG07550.1 - 0.024 14.4 0.0 8.9 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KEG07550.1 - 0.03 14.4 0.0 4.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain CDC48_N PF02359.18 KEG07550.1 - 0.034 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 KEG07550.1 - 0.085 12.6 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain IBR PF01485.21 KEG07551.1 - 5.4e-15 55.4 24.8 7.7e-09 35.7 9.6 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KEG07551.1 - 0.00072 19.8 11.0 0.00072 19.8 11.0 4.8 4 1 1 5 5 5 1 Ring finger domain zf-RING_11 PF17123.5 KEG07551.1 - 0.003 17.3 6.7 0.003 17.3 6.7 3.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEG07551.1 - 0.0071 16.2 8.1 0.0071 16.2 8.1 4.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RACo_linker PF17650.1 KEG07551.1 - 0.023 14.5 1.1 0.72 9.8 0.9 2.6 2 0 0 2 2 2 0 RACo linker region DUF4257 PF14074.6 KEG07552.1 - 0.035 14.3 0.3 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) ANAPC4_WD40 PF12894.7 KEG07553.1 - 0.0078 16.5 0.0 10 6.5 0.0 3.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEG07553.1 - 0.046 13.3 0.6 1.4 8.4 0.3 2.6 1 1 1 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KEG07553.1 - 0.21 12.1 4.6 0.84 10.2 0.2 2.9 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 KEG07553.1 - 0.72 10.8 2.7 36 5.4 0.2 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat baeRF_family7 PF18849.1 KEG07555.1 - 0.19 11.9 0.3 1.3 9.2 0.0 2.0 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 V-ATPase_G PF03179.15 KEG07556.1 - 1.3e-18 67.4 14.7 1.5e-18 67.3 14.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit KI67R PF08065.12 KEG07556.1 - 0.016 15.7 2.5 0.02 15.5 2.5 1.2 1 0 0 1 1 1 0 KI67R (NUC007) repeat ARD PF03079.14 KEG07556.1 - 0.18 12.0 2.4 0.19 11.9 2.4 1.1 1 0 0 1 1 1 0 ARD/ARD' family TF_AP-2 PF03299.14 KEG07556.1 - 0.22 11.5 4.8 0.26 11.2 4.8 1.1 1 0 0 1 1 1 0 Transcription factor AP-2 DUF5401 PF17380.2 KEG07556.1 - 1.5 6.8 12.5 1.7 6.6 12.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Glyco_transf_8 PF01501.20 KEG07558.1 - 5.2e-07 29.5 0.0 4.1e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KEG07558.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Exo_endo_phos PF03372.23 KEG07561.1 - 0.026 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FAM181 PF15238.6 KEG07561.1 - 0.06 13.2 0.6 0.078 12.8 0.6 1.2 1 0 0 1 1 1 0 FAM181 RRN9 PF10680.9 KEG07561.1 - 0.14 12.4 1.0 4.2 7.7 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor AvrM-A PF18241.1 KEG07562.1 - 0.049 14.0 2.2 0.15 12.4 0.3 2.7 2 1 1 3 3 3 0 Flax-rust effector AvrM-A KLRAQ PF10205.9 KEG07562.1 - 0.93 9.8 7.0 1.7 8.9 5.5 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein SNF2_N PF00176.23 KEG07563.1 - 4.3e-66 223.0 0.0 8.8e-66 222.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG07563.1 - 1.4e-18 67.2 0.1 3.3e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG07563.1 - 1.9e-08 34.5 0.0 5.4e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG07563.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KEG07563.1 - 0.0015 17.8 0.0 0.0015 17.8 0.0 1.8 2 0 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase RNA_pol_3_Rpc31 PF11705.8 KEG07563.1 - 0.025 14.8 14.5 0.074 13.3 13.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 KEG07563.1 - 0.037 12.3 13.6 0.06 11.6 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 KEG07563.1 - 0.088 11.3 2.4 0.13 10.8 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SDA1 PF05285.12 KEG07563.1 - 1.2 8.5 17.1 1.8 7.9 17.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEG07563.1 - 3.9 5.6 18.5 5.8 5.0 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KEG07563.1 - 9.4 5.2 21.3 19 4.2 21.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Drc1-Sld2 PF11719.8 KEG07563.1 - 9.6 5.6 17.1 19 4.7 17.1 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Aldedh PF00171.22 KEG07564.1 - 2.4e-129 431.8 0.7 2.8e-129 431.6 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VPS28 PF03997.12 KEG07565.1 - 6.6e-55 185.7 0.3 7.5e-55 185.6 0.3 1.0 1 0 0 1 1 1 1 VPS28 protein DUF1180 PF06679.12 KEG07567.1 - 0.074 13.5 0.9 0.099 13.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Golgin_A5 PF09787.9 KEG07568.1 - 8.1e-12 45.2 11.4 8.1e-12 45.2 11.4 2.3 1 1 1 2 2 2 1 Golgin subfamily A member 5 Spc7 PF08317.11 KEG07568.1 - 0.00033 19.6 8.2 0.00033 19.6 8.2 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein GAS PF13851.6 KEG07568.1 - 0.017 14.5 1.1 0.017 14.5 1.1 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KEG07568.1 - 0.02 14.9 3.0 0.02 14.9 3.0 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KEG07568.1 - 0.042 11.4 24.4 0.062 10.8 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 KEG07568.1 - 0.46 10.7 23.5 1.7 8.9 0.8 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Peptidase_C98 PF15499.6 KEG07568.1 - 1.8 8.0 4.0 2.6 7.5 0.2 2.2 1 1 2 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase YabA PF06156.13 KEG07568.1 - 1.9 9.2 9.1 3.4 8.4 1.7 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 KEG07568.1 - 2 9.0 8.8 7.1 7.2 1.5 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 AAA_13 PF13166.6 KEG07568.1 - 2.1 6.9 10.1 3.9 6.0 10.1 1.4 1 0 0 1 1 1 0 AAA domain BPL_N PF09825.9 KEG07568.1 - 7.2 5.6 7.6 15 4.6 7.5 1.5 1 1 1 2 2 2 0 Biotin-protein ligase, N terminal Herpes_pp85 PF04637.12 KEG07570.1 - 0.22 9.9 0.2 0.28 9.6 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IQ PF00612.27 KEG07572.1 - 4.5e-14 50.9 57.4 0.00013 21.4 1.2 10.0 9 0 0 9 9 9 6 IQ calmodulin-binding motif Med27 PF11571.8 KEG07572.1 - 0.047 14.0 0.3 0.15 12.4 0.3 1.8 1 0 0 1 1 1 0 Mediator complex subunit 27 APP_N PF02177.16 KEG07572.1 - 0.12 12.8 2.3 9.1 6.7 0.0 3.5 2 1 1 3 3 3 0 Amyloid A4 N-terminal heparin-binding ORC6 PF05460.13 KEG07572.1 - 0.43 9.8 2.6 0.88 8.8 2.6 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Telomere_reg-2 PF10193.9 KEG07574.1 - 1.4e-06 28.7 0.5 1e-05 26.0 0.0 2.5 3 0 0 3 3 3 1 Telomere length regulation protein DUF4704 PF15787.5 KEG07577.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) PAP_assoc PF03828.19 KEG07578.1 - 1.9e-16 60.0 0.0 5.4e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase Ribosomal_L16 PF00252.18 KEG07579.1 - 1.2e-15 57.7 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SRPRB PF09439.10 KEG07584.1 - 1.3e-24 86.6 0.0 7.8e-24 84.1 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KEG07584.1 - 3.5e-09 36.3 0.0 3.3e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEG07584.1 - 2.2e-07 30.6 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG07584.1 - 2.5e-05 24.3 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KEG07584.1 - 0.00041 19.6 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit DUF463 PF04317.12 KEG07584.1 - 0.0023 16.9 0.0 0.33 9.8 0.0 2.1 2 0 0 2 2 2 2 YcjX-like family, DUF463 SRP54 PF00448.22 KEG07584.1 - 0.0096 15.6 0.5 0.2 11.3 0.5 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain NAD_binding_3 PF03447.16 KEG07584.1 - 0.026 15.2 0.5 0.11 13.1 0.2 2.0 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AAA_30 PF13604.6 KEG07584.1 - 0.027 14.2 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEG07584.1 - 0.03 14.6 0.0 0.089 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KEG07584.1 - 0.051 13.2 0.4 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 KEG07584.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KEG07584.1 - 0.075 13.2 0.1 0.14 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEG07584.1 - 0.081 13.3 2.8 0.52 10.7 2.6 2.1 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KEG07584.1 - 0.1 12.5 0.2 0.94 9.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KEG07584.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 KEG07584.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KEG07584.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin TsaE PF02367.17 KEG07584.1 - 0.23 11.5 0.2 0.6 10.1 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ANAPC4_WD40 PF12894.7 KEG07585.1 - 2.3e-05 24.6 2.1 2 8.8 0.1 5.2 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG07585.1 - 7.6e-05 23.4 4.2 4.6 8.3 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEG07585.1 - 0.0033 16.4 0.0 0.53 9.2 0.0 2.6 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LIM PF00412.22 KEG07586.1 - 4.4e-05 23.6 1.1 7.5e-05 22.9 1.1 1.4 1 0 0 1 1 1 1 LIM domain DZR PF12773.7 KEG07586.1 - 0.31 11.1 5.1 0.9 9.6 4.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon tRNA_lig_CPD PF08302.11 KEG07587.1 - 8.9e-11 41.7 0.2 1.8e-09 37.4 0.0 2.0 1 1 1 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain DUF3168 PF11367.8 KEG07588.1 - 0.068 13.4 2.1 0.12 12.6 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3168) WD40 PF00400.32 KEG07590.1 - 0.023 15.6 2.3 17 6.4 0.0 4.4 6 0 0 6 6 6 0 WD domain, G-beta repeat Benyvirus_P25 PF05744.11 KEG07590.1 - 0.76 9.0 3.4 0.64 9.3 1.3 1.8 2 0 0 2 2 2 0 Benyvirus P25/P26 protein PerC PF06069.11 KEG07591.1 - 4.9 7.5 9.2 0.21 11.9 0.4 2.9 3 0 0 3 3 3 0 PerC transcriptional activator GTP_cyclohydro2 PF00925.20 KEG07592.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase II Lipase_GDSL_2 PF13472.6 KEG07593.1 - 0.0057 17.1 0.1 0.0089 16.4 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MAM33 PF02330.16 KEG07594.1 - 2.9e-10 40.5 0.0 4.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein AdoHcyase PF05221.17 KEG07596.1 - 3.5e-133 443.3 0.0 5e-74 249.1 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KEG07596.1 - 2.9e-87 290.8 1.3 4.2e-87 290.3 1.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEG07596.1 - 3.9e-10 39.4 0.0 7.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KEG07596.1 - 0.00014 21.5 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KEG07596.1 - 0.00055 20.2 0.2 0.0021 18.3 0.2 2.0 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 KEG07596.1 - 0.0098 16.3 0.2 0.03 14.8 0.2 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Oxidored_nitro PF00148.19 KEG07596.1 - 0.013 14.3 0.1 0.3 9.8 0.1 2.1 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.19 KEG07596.1 - 0.018 14.4 0.4 0.086 12.1 0.4 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PALP PF00291.25 KEG07596.1 - 0.085 12.2 0.5 0.26 10.7 0.2 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme PRD1_DD PF11087.8 KEG07597.1 - 2.4 7.9 13.7 1.1 9.0 2.1 2.3 1 1 1 2 2 2 0 PRD1 phage membrane DNA delivery CEP76-C2 PF15627.6 KEG07600.1 - 0.037 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain Tyr-DNA_phospho PF06087.12 KEG07601.1 - 8.2e-87 291.8 0.0 9.2e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Ras PF00071.22 KEG07602.1 - 3.9e-48 163.1 0.0 5e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG07602.1 - 5.2e-34 117.0 0.2 8.2e-34 116.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG07602.1 - 8.8e-15 54.6 0.2 1.1e-14 54.3 0.2 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG07602.1 - 0.0001 22.4 0.1 0.00026 21.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG07602.1 - 0.00036 20.1 0.1 0.0015 18.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEG07602.1 - 0.00066 19.1 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEG07602.1 - 0.006 16.0 0.0 0.0091 15.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KEG07602.1 - 0.022 14.7 0.1 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KEG07602.1 - 0.065 12.4 0.0 0.079 12.1 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit FAD-oxidase_C PF02913.19 KEG07603.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Hydrolase_3 PF08282.12 KEG07604.1 - 1.1e-44 153.1 0.0 2.8e-44 151.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEG07604.1 - 4.3e-12 46.1 0.2 8.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KEG07604.1 - 9.8e-05 22.7 1.9 0.015 15.6 1.9 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KEG07604.1 - 0.0029 16.8 0.2 0.11 11.6 0.0 2.6 3 0 0 3 3 3 1 Trehalose-phosphatase HAD PF12710.7 KEG07604.1 - 0.051 14.0 1.7 1.3 9.4 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DHHC PF01529.20 KEG07605.1 - 1.9e-26 92.8 1.1 1.9e-26 92.8 1.1 2.7 2 1 1 3 3 3 1 DHHC palmitoyltransferase S1FA PF04689.13 KEG07605.1 - 0.27 11.4 0.2 0.27 11.4 0.2 1.8 2 0 0 2 2 2 0 DNA binding protein S1FA ABC2_membrane_3 PF12698.7 KEG07605.1 - 0.99 8.4 7.2 1.9 7.5 3.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEG07605.1 - 8.2 5.6 8.8 27 3.9 5.7 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Histone PF00125.24 KEG07606.1 - 1.3e-08 35.3 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEG07606.1 - 0.0064 16.7 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aminotran_5 PF00266.19 KEG07607.1 - 0.0041 16.1 0.0 0.0097 14.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V RdRP PF05183.12 KEG07607.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase M20_dimer PF07687.14 KEG07611.1 - 2.6e-17 62.7 0.0 4.8e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase dimerisation domain Hydin_ADK PF17213.3 KEG07613.1 - 8.7 6.6 12.6 0.7 10.1 6.9 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain EF1G PF00647.19 KEG07614.1 - 6.2e-39 132.3 0.2 2e-38 130.7 0.1 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KEG07614.1 - 1.3e-16 60.6 0.8 2.4e-16 59.7 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEG07614.1 - 6.4e-14 52.0 0.1 2e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEG07614.1 - 1.9e-06 28.0 0.3 5.8e-06 26.4 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEG07614.1 - 1.9e-05 25.0 0.0 5.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEG07614.1 - 0.0029 17.6 1.8 0.0081 16.2 0.0 2.5 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain zf-NOSIP PF15906.5 KEG07614.1 - 0.033 14.3 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Ribosomal_60s PF00428.19 KEG07614.1 - 0.52 10.9 7.4 1 10.0 7.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein IATP PF04568.12 KEG07617.1 - 0.013 15.9 0.4 0.013 15.9 0.4 3.9 4 1 0 4 4 4 0 Mitochondrial ATPase inhibitor, IATP Asparaginase PF00710.20 KEG07618.1 - 5.4e-57 192.4 0.0 7.5e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KEG07618.1 - 1.9e-27 95.7 0.0 3.5e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ribosomal_60s PF00428.19 KEG07619.1 - 7.3e-20 71.4 9.1 9.1e-20 71.1 9.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TBCC PF07986.12 KEG07620.1 - 1.6e-33 115.0 14.8 6.3e-14 51.7 0.6 3.7 3 0 0 3 3 3 3 Tubulin binding cofactor C Pkinase PF00069.25 KEG07620.1 - 0.0049 16.3 0.0 0.85 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain CAP_C PF08603.11 KEG07620.1 - 0.036 13.7 3.1 0.27 10.8 0.2 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Kdo PF06293.14 KEG07620.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 KEG07621.1 - 6.1e-16 59.5 0.0 1.2e-14 55.3 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CMV_1a PF12467.8 KEG07621.1 - 0.39 11.1 2.5 0.47 10.8 1.2 1.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Peptidase_C48 PF02902.19 KEG07623.1 - 5.7e-16 59.0 0.0 4.4e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Laminin_EGF PF00053.24 KEG07626.1 - 0.00039 20.5 16.1 0.00039 20.5 16.1 5.7 2 1 2 4 4 4 1 Laminin EGF domain EGF PF00008.27 KEG07626.1 - 0.011 16.0 14.8 0.011 16.0 14.8 5.4 4 1 0 4 4 4 0 EGF-like domain EGF_2 PF07974.13 KEG07626.1 - 0.05 14.0 78.8 0.041 14.2 18.7 5.4 5 0 0 5 5 5 0 EGF-like domain PPR_2 PF13041.6 KEG07628.1 - 4.1e-12 46.1 1.7 1.2e-07 31.8 0.1 4.1 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 KEG07628.1 - 9.8e-09 35.2 0.0 0.00091 19.3 0.0 2.8 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KEG07628.1 - 1.8e-07 30.9 5.7 0.0078 16.4 0.0 4.9 4 1 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KEG07628.1 - 8.9e-06 25.2 0.1 1.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Taxilin PF09728.9 KEG07629.1 - 3.2e-06 26.5 57.1 5.6e-06 25.8 56.7 1.6 1 1 0 1 1 1 1 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.12 KEG07629.1 - 0.00095 19.2 24.2 0.00095 19.2 24.2 4.3 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein DUF1823 PF08853.11 KEG07629.1 - 0.095 12.9 1.7 0.18 12.0 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1823) DUF4400 PF14348.6 KEG07629.1 - 1.2 8.6 7.1 0.59 9.6 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4400) Frankia_peptide PF14407.6 KEG07630.1 - 0.045 13.7 0.4 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. AMNp_N PF10423.9 KEG07631.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Tektin PF03148.14 KEG07632.1 - 0.0035 16.2 4.6 0.0045 15.8 4.6 1.1 1 0 0 1 1 1 1 Tektin family RasGAP_C PF03836.15 KEG07632.1 - 0.0071 16.5 0.4 0.009 16.2 0.4 1.2 1 0 0 1 1 1 1 RasGAP C-terminus DUF3450 PF11932.8 KEG07632.1 - 0.011 15.1 4.7 0.012 14.9 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tho2 PF11262.8 KEG07632.1 - 0.021 14.1 3.3 0.026 13.8 3.3 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Laminin_I PF06008.14 KEG07632.1 - 0.024 14.4 6.2 0.029 14.1 6.2 1.1 1 0 0 1 1 1 0 Laminin Domain I YabA PF06156.13 KEG07632.1 - 0.049 14.3 1.6 0.072 13.7 1.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA T3SSipB PF16535.5 KEG07632.1 - 0.05 14.1 6.1 0.058 13.9 6.1 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB Occludin_ELL PF07303.13 KEG07632.1 - 0.06 14.1 2.9 0.11 13.3 2.9 1.3 1 0 0 1 1 1 0 Occludin homology domain TraF_2 PF13729.6 KEG07632.1 - 0.061 12.7 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF948 PF06103.11 KEG07632.1 - 0.085 13.1 1.0 0.12 12.6 1.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 KEG07632.1 - 0.095 13.1 1.5 0.14 12.5 1.5 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels V_ATPase_I PF01496.19 KEG07632.1 - 0.2 9.5 1.9 0.23 9.3 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.8 KEG07632.1 - 0.35 11.3 9.0 0.47 10.8 9.0 1.3 1 0 0 1 1 1 0 YlqD protein DASH_Spc19 PF08287.11 KEG07632.1 - 0.41 10.5 5.7 0.73 9.7 5.7 1.4 1 1 0 1 1 1 0 Spc19 FapA PF03961.13 KEG07632.1 - 0.47 9.0 2.1 0.51 8.9 2.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlxA PF14282.6 KEG07632.1 - 4.7 7.3 15.1 11 6.0 14.8 1.7 1 1 1 2 2 2 0 FlxA-like protein DUF3847 PF12958.7 KEG07632.1 - 8.8 6.5 9.9 0.92 9.7 4.7 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) RVT_1 PF00078.27 KEG07635.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Microvir_J PF04726.13 KEG07635.1 - 0.5 10.4 2.6 15 5.7 1.6 2.5 2 0 0 2 2 2 0 Microvirus J protein NAC PF01849.18 KEG07637.1 - 7e-19 67.5 0.1 9.6e-19 67.1 0.1 1.2 1 0 0 1 1 1 1 NAC domain MORN PF02493.20 KEG07638.1 - 4.1e-20 70.4 69.9 0.0003 20.5 0.8 9.4 10 0 0 10 10 10 8 MORN repeat CH PF00307.31 KEG07639.1 - 0.00029 21.0 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain ATG16 PF08614.11 KEG07639.1 - 0.00035 20.9 6.1 0.00035 20.9 6.1 5.3 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) SUIM_assoc PF16619.5 KEG07639.1 - 0.17 11.9 21.7 4.6 7.4 9.4 4.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Phage_GP20 PF06810.11 KEG07639.1 - 2.7 7.8 6.7 14 5.5 0.1 3.3 3 0 0 3 3 3 0 Phage minor structural protein GP20 Spt20 PF12090.8 KEG07639.1 - 3.5 7.2 17.3 0.95 9.0 6.9 2.5 2 0 0 2 2 2 0 Spt20 family GCV_T PF01571.21 KEG07640.1 - 3.6e-76 255.9 0.0 4.3e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KEG07640.1 - 1.6e-20 72.8 0.6 2.8e-20 72.0 0.6 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aminotran_1_2 PF00155.21 KEG07641.1 - 1.1e-75 255.1 0.0 1.2e-75 254.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KEG07641.1 - 0.00032 19.6 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 KEG07641.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KEG07641.1 - 0.055 12.0 0.0 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEG07642.1 - 6.3e-65 219.7 0.0 7.1e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEG07642.1 - 1.3e-05 24.7 0.0 2.9e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KEG07642.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEG07642.1 - 0.0094 14.5 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Gp_dh_C PF02800.20 KEG07643.1 - 3.4e-64 215.2 0.2 4.8e-64 214.7 0.2 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KEG07643.1 - 5.3e-41 139.1 0.3 1e-40 138.1 0.3 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KEG07643.1 - 0.0024 18.0 1.1 0.0098 16.0 0.4 2.4 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TgMIC1 PF11476.8 KEG07643.1 - 0.007 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 2-Hacid_dh_C PF02826.19 KEG07643.1 - 0.049 13.0 0.1 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OstA PF03968.14 KEG07643.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 OstA-like protein Aminotran_1_2 PF00155.21 KEG07644.1 - 1.9e-22 80.0 0.0 2e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Oxysterol_BP PF01237.18 KEG07645.1 - 9.8e-43 146.4 0.0 1.7e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein CKAP2_C PF15297.6 KEG07645.1 - 0.28 10.2 0.0 0.42 9.7 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Pentapeptide PF00805.22 KEG07646.1 - 0.00011 21.7 9.0 0.0082 15.8 0.2 4.8 5 0 0 5 5 5 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KEG07646.1 - 0.0009 19.4 14.2 0.011 15.8 9.3 3.2 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KEG07646.1 - 0.0016 18.6 21.6 0.43 10.8 7.9 4.2 3 1 1 4 4 4 3 Pentapeptide repeats (9 copies) DAGK_cat PF00781.24 KEG07647.1 - 2.2e-15 56.4 0.0 2.4e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain Minor_capsid_1 PF10665.9 KEG07649.1 - 0.045 14.0 0.3 1.4 9.2 0.1 2.1 1 1 1 2 2 2 0 Minor capsid protein Bac_GDH PF05088.12 KEG07650.1 - 0.00048 17.8 4.3 0.00065 17.4 4.3 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase Csm2_III-A PF03750.13 KEG07650.1 - 0.1 13.4 1.3 0.23 12.3 1.3 1.6 1 0 0 1 1 1 0 Csm2 Type III-A Ribonuc_2-5A PF06479.12 KEG07650.1 - 0.22 11.7 2.9 0.39 10.9 2.9 1.4 1 0 0 1 1 1 0 Ribonuclease 2-5A DUF445 PF04286.12 KEG07650.1 - 0.22 11.3 5.8 0.31 10.8 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AcetDehyd-dimer PF09290.11 KEG07650.1 - 0.3 11.3 1.3 1.4 9.1 1.1 2.2 1 1 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF948 PF06103.11 KEG07650.1 - 0.79 10.0 2.5 15 6.0 0.0 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.18 KEG07650.1 - 1.3 9.3 9.3 6.8 7.1 0.0 3.7 3 1 0 4 4 4 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 KEG07650.1 - 1.8 6.4 6.7 2.3 6.1 6.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.6 KEG07650.1 - 2.5 8.1 6.7 5.1 7.1 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 KEG07650.1 - 5.1 7.2 9.1 13 5.8 4.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KEG07650.1 - 7.4 6.5 8.4 7.4 6.5 7.0 1.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Jnk-SapK_ap_N PF09744.9 KEG07650.1 - 7.9 6.7 22.4 3.4 7.9 17.0 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 KEG07650.1 - 8.8 5.6 8.4 11 5.2 8.4 1.2 1 0 0 1 1 1 0 FAM76 protein Sec1 PF00995.23 KEG07651.1 - 3.8e-95 320.3 0.0 4.5e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Mucin PF01456.17 KEG07652.1 - 3.6 7.6 16.7 0.062 13.3 1.4 2.7 2 1 0 2 2 2 0 Mucin-like glycoprotein GRASP55_65 PF04495.14 KEG07653.1 - 2.6e-48 163.9 0.0 1e-33 116.6 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ PF00595.24 KEG07653.1 - 3e-05 24.3 0.0 0.00034 20.9 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KEG07653.1 - 0.0034 17.7 0.0 0.0091 16.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KEG07653.1 - 0.0081 16.0 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain NYAP_N PF15439.6 KEG07654.1 - 0.039 13.2 0.1 0.083 12.1 0.1 1.6 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter PcfK PF14058.6 KEG07654.1 - 0.071 13.4 0.4 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 PcfK-like protein IQCJ-SCHIP1 PF15157.6 KEG07655.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif NCA2 PF08637.10 KEG07656.1 - 1.4e-53 182.0 1.7 2.1e-53 181.4 1.7 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF2524 PF10732.9 KEG07656.1 - 0.11 12.8 1.6 0.38 11.1 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) dCache_2 PF08269.11 KEG07656.1 - 0.23 10.6 0.1 0.41 9.8 0.1 1.3 1 0 0 1 1 1 0 Cache domain Pkinase PF00069.25 KEG07657.1 - 3.1e-43 148.1 0.0 4.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07657.1 - 1.5e-28 99.8 0.0 1.7e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG07657.1 - 0.0089 16.0 0.3 4.2 7.2 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG07657.1 - 0.055 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EutN_CcmL PF03319.13 KEG07657.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome 5_3_exonuc PF01367.20 KEG07659.1 - 0.0089 16.6 0.5 0.014 16.0 0.5 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Serinc PF03348.15 KEG07660.1 - 0.024 13.6 0.1 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PqiA PF04403.13 KEG07661.1 - 4.7e-12 46.0 3.9 4.7e-12 46.0 3.9 2.6 2 0 0 2 2 2 2 Paraquat-inducible protein A IMPa_N_2 PF18650.1 KEG07662.1 - 0.047 12.9 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Epimerase PF01370.21 KEG07663.1 - 2.9e-41 141.5 0.0 3.6e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEG07663.1 - 1.1e-40 140.0 0.0 1.2e-39 136.6 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEG07663.1 - 6.5e-13 48.5 0.0 6.1e-12 45.3 0.1 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEG07663.1 - 8.2e-12 44.7 0.0 6.4e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEG07663.1 - 3e-11 43.0 0.0 5e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KEG07663.1 - 1.1e-05 25.4 0.3 2.6e-05 24.2 0.3 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KEG07663.1 - 3.7e-05 23.0 0.0 0.00016 20.9 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEG07663.1 - 0.021 14.7 0.6 3.3 7.6 0.1 2.2 1 1 1 2 2 2 0 NAD(P)H-binding PRP21_like_P PF12230.8 KEG07664.1 - 0.13 12.2 0.1 0.65 9.8 0.2 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein CDC45 PF02724.14 KEG07665.1 - 1.1e-75 255.3 0.7 1.3e-75 255.0 0.7 1.0 1 0 0 1 1 1 1 CDC45-like protein Rrn6 PF10214.9 KEG07665.1 - 0.019 13.5 1.0 0.029 12.9 1.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1168 PF06658.12 KEG07665.1 - 0.029 14.2 8.5 0.061 13.1 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Zap1_zf2 PF18217.1 KEG07665.1 - 0.14 12.2 1.4 21 5.2 0.3 3.0 3 0 0 3 3 3 0 Zap1 zinc finger 2 Pox_LP_H2 PF03356.15 KEG07665.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Viral late protein H2 Vasculin PF15337.6 KEG07665.1 - 0.27 12.1 4.5 0.6 11.0 3.7 2.0 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 CSRNP_N PF16019.5 KEG07665.1 - 0.67 9.8 4.5 1.3 8.9 4.5 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PNISR PF15996.5 KEG07665.1 - 0.7 10.1 7.4 1.8 8.8 7.4 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CNDH2_C PF16858.5 KEG07665.1 - 2 8.2 8.2 0.68 9.8 5.1 1.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PBP1_TM PF14812.6 KEG07665.1 - 9.6 6.7 12.0 25 5.3 12.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Septum_form PF13845.6 KEG07666.1 - 0.0016 18.0 0.6 0.0017 17.9 0.6 1.2 1 0 0 1 1 1 1 Septum formation PUB_1 PF18486.1 KEG07666.1 - 0.084 12.7 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain T3SSipB PF16535.5 KEG07668.1 - 0.61 10.5 50.6 0.084 13.3 4.9 3.6 2 1 1 4 4 4 0 Type III cell invasion protein SipB Mucin PF01456.17 KEG07668.1 - 3.5 7.6 54.6 0.12 12.4 16.7 4.2 3 2 0 3 3 3 0 Mucin-like glycoprotein DivIVA PF05103.13 KEG07668.1 - 3.8 7.6 30.4 1.1 9.3 0.9 3.8 2 1 2 4 4 4 0 DivIVA protein EPO_TPO PF00758.18 KEG07668.1 - 7.2 6.6 7.8 3.2 7.8 0.3 2.9 2 1 1 3 3 3 0 Erythropoietin/thrombopoietin Sec8_exocyst PF04048.14 KEG07668.1 - 7.8 6.4 10.3 2.3 8.1 0.6 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Mucin PF01456.17 KEG07670.1 - 0.0043 17.1 5.5 0.0043 17.1 5.5 3.2 1 1 0 2 2 2 1 Mucin-like glycoprotein BORCS8 PF10167.9 KEG07670.1 - 0.35 10.8 5.7 4.6 7.2 0.9 2.9 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 Uteroglobin PF01099.17 KEG07670.1 - 0.43 11.0 3.0 0.77 10.1 1.2 2.4 2 1 0 2 2 2 0 Uteroglobin family GARP PF16731.5 KEG07670.1 - 0.75 9.5 53.1 0.029 14.0 6.5 4.0 2 1 2 4 4 4 0 Glutamic acid/alanine-rich protein of Trypanosoma Na_Ca_ex_C PF16494.5 KEG07670.1 - 1 9.8 5.4 0.72 10.3 2.9 2.0 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain FAA_hydro_N_2 PF18288.1 KEG07670.1 - 7.3 7.1 6.8 4.6 7.7 0.8 3.2 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF1664 PF07889.12 KEG07670.1 - 8.3 6.5 8.1 13 5.9 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4364 PF14277.6 KEG07672.1 - 0.0073 16.1 0.6 0.015 15.0 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) ATG16 PF08614.11 KEG07672.1 - 0.088 13.0 31.4 2.5 8.3 8.6 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KEG07672.1 - 0.12 12.4 9.3 0.2 11.7 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 KEG07672.1 - 0.27 11.3 25.1 0.054 13.6 8.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.11 KEG07672.1 - 1.1 9.1 4.8 1.7 8.4 0.4 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 KEG07672.1 - 1.1 9.3 21.8 8.6 6.4 20.7 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 KEG07672.1 - 1.6 8.1 22.4 2.2 7.7 22.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 MPS2 PF17060.5 KEG07672.1 - 1.7 7.8 13.2 1.4 8.1 3.7 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 Spc29 PF17082.5 KEG07672.1 - 1.8 8.3 10.7 2.4 7.9 10.7 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 IFP_35_N PF07334.13 KEG07672.1 - 1.8 8.7 12.0 4.6 7.4 0.9 3.2 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.11 KEG07672.1 - 3.4 6.5 24.7 4.8 6.0 9.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.12 KEG07672.1 - 4.9 7.5 19.6 1.6 9.1 6.7 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 KEG07672.1 - 5.7 4.7 8.7 7.1 4.4 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SH3BP5 PF05276.14 KEG07674.1 - 0.036 13.9 2.9 0.054 13.3 2.9 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Allexi_40kDa PF05549.11 KEG07674.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Pkinase PF00069.25 KEG07675.1 - 4e-48 164.1 0.0 7.9e-48 163.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07675.1 - 1.3e-28 100.0 0.0 2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG07675.1 - 3e-06 26.8 0.0 6.2e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG07675.1 - 0.003 16.4 0.0 0.0091 14.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF2937 PF11157.8 KEG07675.1 - 0.019 14.7 0.5 0.033 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF719 PF05334.13 KEG07675.1 - 0.028 14.6 5.1 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) APH PF01636.23 KEG07675.1 - 0.1 12.5 1.9 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mcp5_PH PF12814.7 KEG07676.1 - 4.8e-13 49.3 0.0 8.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3086 PF11285.8 KEG07676.1 - 0.072 12.2 1.5 0.12 11.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF3395 PF11875.8 KEG07677.1 - 6.7e-37 126.8 0.0 1.5e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KEG07677.1 - 7.3e-17 61.3 0.3 2e-16 59.8 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain PIF1 PF05970.14 KEG07678.1 - 0.014 14.6 0.2 0.53 9.4 0.0 2.6 2 1 0 2 2 2 0 PIF1-like helicase XAF1_C PF18608.1 KEG07678.1 - 0.031 13.8 2.7 0.25 10.9 2.4 2.4 1 1 1 2 2 2 0 XIAP-associated factor 1 C-terminal domain OrsD PF12013.8 KEG07678.1 - 0.047 14.1 0.2 0.047 14.1 0.2 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_30 PF13604.6 KEG07678.1 - 0.058 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KEG07678.1 - 0.064 13.1 0.1 0.78 9.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein zf_UBZ PF18439.1 KEG07678.1 - 0.086 12.5 3.4 6.4 6.5 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SRP54 PF00448.22 KEG07678.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KEG07678.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DZR PF12773.7 KEG07678.1 - 0.37 10.8 4.5 11 6.2 4.4 2.8 1 1 1 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KEG07678.1 - 3.1 7.8 6.4 0.41 10.6 0.7 2.6 2 1 1 3 3 3 0 Nudix N-terminal DUF3246 PF11596.8 KEG07681.1 - 0.11 11.9 1.0 0.11 11.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MFAP1 PF06991.11 KEG07681.1 - 2 8.2 5.3 0.44 10.3 0.6 1.8 1 1 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing BRE1 PF08647.11 KEG07682.1 - 0.00073 19.6 1.6 0.00073 19.6 1.6 7.4 4 3 1 7 7 7 1 BRE1 E3 ubiquitin ligase FPV060 PF17614.2 KEG07682.1 - 0.14 11.6 0.0 0.42 10.0 0.0 1.8 1 0 0 1 1 1 0 Viral CC-type chemokine Fam20C PF06702.12 KEG07682.1 - 0.48 10.2 6.6 0.66 9.8 1.1 2.5 1 1 1 2 2 2 0 Golgi casein kinase, C-terminal, Fam20 DUF1664 PF07889.12 KEG07682.1 - 2.7 8.0 45.0 0.47 10.5 1.3 7.4 5 2 3 8 8 8 0 Protein of unknown function (DUF1664) SNARE_assoc PF09335.11 KEG07685.1 - 4.9e-19 69.0 4.8 4.9e-19 69.0 4.8 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein TMEM208_SND2 PF05620.11 KEG07685.1 - 0.33 10.7 3.1 0.32 10.7 1.1 1.9 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 FtsK_4TM PF13491.6 KEG07685.1 - 2.2 8.0 13.3 1 9.0 8.4 2.5 2 1 1 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE Acetyltransf_1 PF00583.25 KEG07686.1 - 1.9e-12 47.4 0.1 2.1e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG07686.1 - 2e-06 27.7 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEG07686.1 - 2.3e-05 24.7 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG07686.1 - 4.2e-05 23.4 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KEG07686.1 - 0.0039 17.9 0.6 0.005 17.5 0.6 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Jnk-SapK_ap_N PF09744.9 KEG07687.1 - 0.1 12.8 14.9 0.18 12.0 14.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 KEG07687.1 - 0.14 12.7 0.2 0.37 11.3 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KEG07687.1 - 0.2 11.0 10.6 0.38 10.1 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KEG07687.1 - 1.8 7.5 7.6 3.6 6.6 7.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 KEG07687.1 - 3.6 8.0 7.8 45 4.5 0.9 3.8 3 1 1 4 4 4 0 Csm1 N-terminal domain XhlA PF10779.9 KEG07690.1 - 9.9 6.5 7.8 2.9 8.2 0.0 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Mucin PF01456.17 KEG07691.1 - 0.00054 20.0 1.2 0.00054 20.0 1.2 4.3 2 1 0 2 2 2 1 Mucin-like glycoprotein GARP PF16731.5 KEG07692.1 - 8 6.1 94.3 0.67 9.6 13.8 4.8 1 1 3 4 4 4 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF677 PF05055.12 KEG07694.1 - 0.18 10.7 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) COX15-CtaA PF02628.15 KEG07700.1 - 6.8e-102 340.8 10.4 7.9e-102 340.6 10.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF716 PF04819.12 KEG07700.1 - 0.22 11.1 4.9 0.17 11.6 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF716) HCMV_UL124 PF17609.2 KEG07701.1 - 0.044 14.0 0.4 0.05 13.8 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function GEMIN8 PF15348.6 KEG07702.1 - 0.076 13.3 0.1 0.076 13.3 0.1 2.7 2 1 1 3 3 3 0 Gemini of Cajal bodies-associated protein 8 Peptidase_M24 PF00557.24 KEG07705.1 - 0.029 14.0 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase family M24 C1_2 PF03107.16 KEG07705.1 - 0.04 14.3 1.7 0.04 14.3 1.7 1.8 3 0 0 3 3 3 0 C1 domain zf-RING_2 PF13639.6 KEG07705.1 - 0.21 11.9 6.6 0.48 10.8 6.6 1.7 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 KEG07705.1 - 0.22 11.4 9.3 0.058 13.3 6.1 1.8 2 1 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 KEG07705.1 - 1.1 9.2 7.2 1 9.3 5.9 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PI3Ka PF00613.20 KEG07706.1 - 9.1e-48 162.1 0.5 1.6e-47 161.3 0.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KEG07706.1 - 2.7e-40 138.8 0.0 3.1e-39 135.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 KEG07706.1 - 6.9e-07 29.4 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 KEG07706.1 - 4.8e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF218 PF02698.17 KEG07707.1 - 0.00016 21.7 0.0 0.00031 20.7 0.0 1.5 1 1 0 1 1 1 1 DUF218 domain KH_6 PF15985.5 KEG07708.1 - 7.2e-11 42.3 1.5 7.2e-11 42.3 1.5 2.0 3 0 0 3 3 3 1 KH domain FUSC_2 PF13515.6 KEG07710.1 - 5.5e-07 29.8 10.7 5.5e-07 29.8 10.7 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like TPR_1 PF00515.28 KEG07711.1 - 0.00044 19.9 0.3 0.05 13.5 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG07711.1 - 0.00061 20.0 0.4 0.001 19.3 0.3 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG07711.1 - 0.00078 19.5 0.3 0.16 12.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG07711.1 - 0.0028 18.3 1.7 0.13 13.2 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG07711.1 - 0.0046 17.0 3.2 0.18 12.0 0.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG07711.1 - 0.091 12.8 1.1 0.82 9.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG07711.1 - 0.52 11.1 4.6 3.5 8.5 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DNA_repr_REX1B PF14966.6 KEG07712.1 - 7.3e-05 23.4 0.2 0.00015 22.3 0.2 1.6 1 0 0 1 1 1 1 DNA repair REX1-B HBS1_N PF08938.10 KEG07712.1 - 0.1 12.9 3.1 0.13 12.6 1.3 2.2 2 1 0 2 2 2 0 HBS1 N-terminus DFP PF04127.15 KEG07713.1 - 6.2e-20 71.8 0.0 1.3e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein PAC3 PF10178.9 KEG07714.1 - 2.8e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Peptidase_M32 PF02074.15 KEG07715.1 - 2.7e-164 547.5 0.0 3.1e-164 547.4 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Vps55 PF04133.14 KEG07716.1 - 7.3e-23 80.8 5.0 8.2e-23 80.6 5.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Ribosomal_L7Ae PF01248.26 KEG07717.1 - 2e-26 91.6 2.8 4.2e-22 77.7 1.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KEG07717.1 - 0.059 13.3 2.1 0.19 11.6 0.1 2.3 1 1 1 2 2 2 0 PELOTA RNA binding domain Lactamase_B_2 PF12706.7 KEG07720.1 - 1.1e-08 34.8 0.3 2.6e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KEG07720.1 - 0.00034 20.2 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Pkinase PF00069.25 KEG07723.1 - 9.2e-54 182.6 0.0 1.2e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07723.1 - 1.6e-35 122.7 0.1 2.1e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG07723.1 - 2.5e-09 37.6 0.0 4.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KEG07723.1 - 8.4e-07 29.4 0.1 3.3e-05 24.2 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 KEG07723.1 - 1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KEG07723.1 - 0.021 15.2 0.5 1.2 9.5 0.5 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain DUF309 PF03745.14 KEG07723.1 - 0.24 11.1 1.9 31 4.4 1.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF309) SGP PF17228.2 KEG07726.1 - 0.047 14.5 0.3 0.12 13.2 0.3 1.6 1 0 0 1 1 1 0 Sulphur globule protein HEPN_SAV_6107 PF18726.1 KEG07728.1 - 0.038 14.5 1.0 0.046 14.2 1.0 1.2 1 0 0 1 1 1 0 SAV_6107-like HEPN TPR_16 PF13432.6 KEG07728.1 - 0.34 11.6 4.9 6.7 7.5 3.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat XPG_I PF00867.18 KEG07731.1 - 1.4e-19 70.2 0.1 2.6e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KEG07731.1 - 1.8e-16 60.5 0.0 8.4e-16 58.3 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KEG07731.1 - 0.00031 20.3 0.1 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing CppA_N PF14506.6 KEG07731.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal DUF1326 PF07040.11 KEG07731.1 - 0.08 13.0 0.2 0.25 11.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) TPR_2 PF07719.17 KEG07733.1 - 2.9e-05 23.9 0.3 0.087 13.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG07733.1 - 0.00019 21.6 2.8 0.00072 19.8 2.2 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG07733.1 - 0.0018 18.0 0.2 0.045 13.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEG07733.1 - 0.042 13.7 5.3 3.7 7.5 3.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DOT1 PF08123.13 KEG07735.1 - 2.1e-22 79.7 0.0 2.3e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KEG07735.1 - 3e-06 27.1 0.0 3.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG07735.1 - 1.4e-05 25.7 0.0 2.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG07735.1 - 3e-05 24.6 0.0 4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEG07735.1 - 0.0002 21.4 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEG07735.1 - 0.0037 16.6 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KEG07735.1 - 0.0068 17.1 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG07735.1 - 0.022 14.6 0.0 0.026 14.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF4268 PF14088.6 KEG07735.1 - 0.023 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) MTS PF05175.14 KEG07735.1 - 0.051 13.1 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Stork_head PF10264.9 KEG07735.1 - 0.094 12.9 0.0 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain AdoMet_MTase PF07757.13 KEG07735.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KEG07735.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KEG07735.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Isy1 PF06246.12 KEG07736.1 - 7.9e-26 91.2 7.8 2.7e-25 89.4 7.8 1.8 1 1 0 1 1 1 1 Isy1-like splicing family EMP70 PF02990.16 KEG07737.1 - 1.6e-165 551.7 7.9 2.2e-165 551.3 7.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 H-kinase_dim PF02895.14 KEG07739.1 - 0.47 10.9 3.3 0.58 10.6 1.0 2.5 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Syntaxin-6_N PF09177.11 KEG07739.1 - 0.5 11.0 6.1 11 6.6 0.1 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TBCA PF02970.16 KEG07739.1 - 3.9 7.9 7.4 2.6 8.4 0.3 3.2 4 0 0 4 4 4 0 Tubulin binding cofactor A Mucin PF01456.17 KEG07740.1 - 9.1e-10 38.7 8.1 2.8e-06 27.4 2.5 2.7 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF3123 PF11321.8 KEG07740.1 - 0.0089 16.7 6.7 0.69 10.6 0.1 3.5 2 1 2 4 4 4 2 Protein of unknown function (DUF3123) Phage_tube PF04985.14 KEG07741.1 - 0.059 13.1 3.6 0.23 11.2 0.0 2.7 3 0 0 3 3 3 0 Phage tail tube protein FII DUF1192 PF06698.11 KEG07742.1 - 0.0022 18.0 3.5 0.0022 18.0 3.5 3.9 4 2 1 5 5 5 1 Protein of unknown function (DUF1192) Radical_SAM PF04055.21 KEG07742.1 - 0.51 10.7 2.7 0.39 11.1 0.6 1.9 2 1 0 2 2 2 0 Radical SAM superfamily Rx_N PF18052.1 KEG07742.1 - 1.7 9.0 14.1 5.8 7.3 5.7 3.3 2 1 0 2 2 2 0 Rx N-terminal domain CheZ PF04344.13 KEG07742.1 - 2 8.3 26.2 0.015 15.2 8.4 2.7 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ HGD-D PF06050.13 KEG07742.1 - 10 5.8 18.0 0.95 9.2 9.6 2.4 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component Amastin PF07344.11 KEG07743.1 - 6.2e-07 29.4 2.5 6.2e-07 29.4 2.5 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Cornichon PF03311.14 KEG07744.1 - 3e-24 85.7 3.5 3e-24 85.7 3.5 1.7 1 1 1 2 2 2 1 Cornichon protein B12D PF06522.11 KEG07746.1 - 0.055 13.3 0.0 9.3 6.1 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit LRR_6 PF13516.6 KEG07747.1 - 0.09 12.9 0.9 2.8 8.2 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich repeat Varsurf_PPLC PF03490.13 KEG07749.1 - 9.2e-27 92.8 0.2 2.2e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.19 KEG07749.1 - 0.0026 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain AAA_2 PF07724.14 KEG07750.1 - 2.7e-57 193.6 0.1 1.8e-55 187.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KEG07750.1 - 6.9e-38 128.7 2.5 6.9e-38 128.7 2.5 3.7 4 1 1 5 5 4 1 AAA lid domain AAA PF00004.29 KEG07750.1 - 1.4e-26 93.5 0.0 5.2e-13 49.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KEG07750.1 - 2e-21 75.8 0.5 7.9e-20 70.7 0.0 3.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KEG07750.1 - 3e-16 59.7 0.2 4e-11 43.1 0.0 3.6 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KEG07750.1 - 5e-15 55.4 3.8 9e-08 32.1 0.0 3.4 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 KEG07750.1 - 9.9e-10 38.4 0.1 1.9e-06 27.7 0.0 3.3 3 2 0 3 3 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KEG07750.1 - 1.3e-08 35.4 14.5 0.00055 20.4 0.1 5.2 4 2 1 6 6 4 2 AAA ATPase domain IstB_IS21 PF01695.17 KEG07750.1 - 3.8e-08 33.3 0.0 0.013 15.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KEG07750.1 - 1.6e-07 31.0 0.0 0.0066 16.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KEG07750.1 - 3e-07 30.8 2.6 0.019 15.3 0.0 4.3 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KEG07750.1 - 1.2e-06 28.6 0.0 0.012 15.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KEG07750.1 - 1.8e-05 24.7 0.0 0.062 13.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 KEG07750.1 - 3.3e-05 23.7 1.3 0.27 11.0 0.0 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEG07750.1 - 4.6e-05 23.6 0.1 0.22 11.7 0.0 4.1 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 KEG07750.1 - 4.7e-05 22.8 0.1 0.044 13.1 0.0 3.7 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 KEG07750.1 - 6.1e-05 22.5 0.1 0.87 8.9 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 KEG07750.1 - 9.5e-05 22.6 0.0 0.56 10.4 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KEG07750.1 - 0.0001 22.3 0.0 1.5 8.8 0.0 3.4 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KEG07750.1 - 0.00017 20.9 0.1 0.098 11.8 0.0 2.9 2 1 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 KEG07750.1 - 0.00032 21.1 0.4 0.95 9.9 0.0 3.5 4 0 0 4 4 2 1 RNA helicase AAA_18 PF13238.6 KEG07750.1 - 0.00033 21.2 0.1 0.24 11.9 0.0 3.8 4 0 0 4 4 2 1 AAA domain DUF815 PF05673.13 KEG07750.1 - 0.00041 19.6 0.0 2 7.5 0.0 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 KEG07750.1 - 0.00051 19.9 0.2 0.27 11.1 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KEG07750.1 - 0.00055 19.8 0.4 3.3 7.5 0.0 4.0 4 0 0 4 4 4 1 Bacterial dnaA protein ATPase_2 PF01637.18 KEG07750.1 - 0.00057 19.9 5.7 1.5 8.6 0.0 4.5 3 2 0 5 5 4 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KEG07750.1 - 0.0015 18.5 0.2 6 6.7 0.0 3.6 4 0 0 4 4 3 0 RsgA GTPase AAA_19 PF13245.6 KEG07750.1 - 0.0021 18.4 0.2 0.57 10.5 0.3 3.4 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KEG07750.1 - 0.0031 18.0 3.3 1.5 9.3 0.0 4.4 5 1 0 5 5 3 1 ABC transporter ResIII PF04851.15 KEG07750.1 - 0.0038 17.2 0.0 0.36 10.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 KEG07750.1 - 0.0061 16.5 0.1 4.1 7.3 0.0 3.2 3 0 0 3 3 2 0 NTPase DNA_pol3_delta2 PF13177.6 KEG07750.1 - 0.0089 15.8 0.0 1 9.1 0.0 3.2 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_29 PF13555.6 KEG07750.1 - 0.0091 15.7 0.1 6.3 6.6 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEG07750.1 - 0.011 16.3 20.5 0.59 10.6 0.0 4.4 3 1 1 4 4 4 0 AAA domain AAA_30 PF13604.6 KEG07750.1 - 0.015 15.0 0.4 4.7 6.9 0.0 3.2 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEG07750.1 - 0.022 15.0 1.3 9.2 6.5 0.0 4.0 4 1 0 4 4 3 0 AAA domain PhoH PF02562.16 KEG07750.1 - 0.045 13.2 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein DnaB_C PF03796.15 KEG07750.1 - 0.046 13.0 1.6 1.9 7.8 0.0 3.0 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain ANAPC5 PF12862.7 KEG07750.1 - 0.062 13.4 0.4 3 8.0 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 AAA_24 PF13479.6 KEG07750.1 - 0.093 12.4 0.0 15 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 KEG07750.1 - 0.096 11.5 14.4 0.18 10.6 14.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 KEG07750.1 - 0.12 12.7 6.2 0.29 11.4 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 KEG07750.1 - 0.13 11.6 0.4 0.41 10.0 0.3 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus AAA_13 PF13166.6 KEG07750.1 - 0.33 9.6 8.1 0.61 8.7 8.1 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KEG07750.1 - 0.42 10.7 6.5 1 9.4 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain V_ATPase_I PF01496.19 KEG07750.1 - 0.81 7.5 4.7 1.3 6.8 4.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 KEG07750.1 - 1.6 9.0 17.4 0.55 10.5 4.8 3.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4407 PF14362.6 KEG07750.1 - 1.7 8.0 7.2 3.2 7.0 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 KEG07750.1 - 5.5 7.5 12.0 16 6.0 1.7 2.9 2 0 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 KEG07750.1 - 6.6 7.3 15.7 26 5.3 15.1 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KEG07750.1 - 8.6 6.9 9.7 4 8.0 3.3 3.3 3 1 0 3 3 1 0 Nucleopolyhedrovirus P10 protein DUF3149 PF11346.8 KEG07751.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF4381 PF14316.6 KEG07751.1 - 0.092 13.0 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) WD40 PF00400.32 KEG07752.1 - 3.3e-30 103.7 18.0 1.4e-08 35.2 0.2 7.0 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG07752.1 - 6.9e-15 55.1 4.3 4.9e-06 26.7 0.3 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEG07752.1 - 4.4e-09 36.5 0.0 8.8e-05 22.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 KEG07752.1 - 0.022 14.7 0.1 4.2 7.2 0.0 2.6 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KEG07752.1 - 0.066 12.2 0.0 0.29 10.0 0.0 2.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PAP2 PF01569.21 KEG07753.1 - 4.5e-19 68.6 1.5 4.5e-19 68.6 1.5 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KEG07753.1 - 0.0011 18.7 8.8 0.0015 18.2 8.8 1.3 1 0 0 1 1 1 1 PAP2 superfamily RseC_MucC PF04246.12 KEG07753.1 - 6.2 6.8 7.6 2.6 8.0 0.9 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF212 PF02681.14 KEG07753.1 - 6.6 6.9 7.1 24 5.1 0.9 3.0 1 1 2 3 3 3 0 Divergent PAP2 family Hydrolase_4 PF12146.8 KEG07754.1 - 1.2e-14 54.1 0.0 7.9e-12 45.0 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KEG07754.1 - 8.4e-12 45.2 0.0 1.9e-09 37.5 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KEG07754.1 - 4.2e-09 36.4 2.5 4.2e-06 26.6 0.1 2.4 2 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEG07754.1 - 1.1e-06 28.3 0.0 8.8e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KEG07754.1 - 1.9e-05 23.5 0.0 0.0042 15.8 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KEG07754.1 - 0.00035 21.3 0.2 0.00047 20.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.9 KEG07754.1 - 0.0016 17.1 0.0 0.0081 14.9 0.0 1.8 1 1 1 2 2 2 1 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.11 KEG07754.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KEG07754.1 - 0.02 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF4637 PF15470.6 KEG07754.1 - 0.051 13.3 3.8 0.084 12.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FSH1 PF03959.13 KEG07754.1 - 0.092 12.4 0.1 0.092 12.4 0.1 2.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 KEG07754.1 - 0.13 11.8 0.1 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family RabGAP-TBC PF00566.18 KEG07755.1 - 2e-52 178.0 0.0 2.8e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC_trans_aux PF03886.13 KEG07755.1 - 0.022 14.4 0.1 0.09 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC-type transport auxiliary lipoprotein component PP2C PF00481.21 KEG07756.1 - 2.9e-45 154.9 0.1 3.5e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEG07756.1 - 2.3e-05 24.4 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Peptidase_S48 PF03574.15 KEG07757.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Peptidase family S48 BCS1_N PF08740.11 KEG07758.1 - 3.5e-34 118.4 5.2 5.4e-34 117.8 5.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KEG07758.1 - 3.9e-18 66.1 0.0 1.2e-17 64.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG07758.1 - 0.0027 18.1 5.0 0.016 15.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 KEG07758.1 - 0.0029 17.6 0.0 0.065 13.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 KEG07758.1 - 0.0065 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KEG07758.1 - 0.0073 16.7 0.0 0.065 13.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KEG07758.1 - 0.012 15.3 0.1 0.052 13.3 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KEG07758.1 - 0.02 14.8 0.0 0.34 10.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_5 PF07728.14 KEG07758.1 - 0.02 14.9 0.1 0.069 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KEG07758.1 - 0.029 14.9 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KEG07758.1 - 0.032 14.4 0.0 0.087 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEG07758.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.6 KEG07760.1 - 1.3e-11 44.2 14.7 2e-11 43.6 14.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG07760.1 - 2.1e-07 30.7 12.8 3.3e-07 30.1 12.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEG07760.1 - 0.0011 18.8 14.9 0.0018 18.2 14.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG07760.1 - 1.2 9.2 13.4 1.5 8.9 9.9 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-met2 PF12907.7 KEG07761.1 - 2.1e-05 24.6 1.0 2.3e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 KEG07761.1 - 0.003 18.4 9.1 0.003 18.4 9.1 1.6 2 0 0 2 2 2 1 4F5 protein family zf-Di19 PF05605.12 KEG07761.1 - 0.016 15.5 0.4 0.024 14.9 0.4 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF_2 PF15965.5 KEG07761.1 - 0.045 14.2 0.4 0.075 13.5 0.4 1.5 1 1 0 1 1 1 0 TRAF-like zinc-finger Isochorismatase PF00857.20 KEG07762.1 - 1.9e-12 47.7 1.1 8e-12 45.7 1.1 1.8 1 1 0 1 1 1 1 Isochorismatase family Inositol_P PF00459.25 KEG07765.1 - 5.8e-22 78.5 0.0 1.3e-21 77.3 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DUF4588 PF15251.6 KEG07766.1 - 0.0008 19.3 0.7 0.0025 17.6 0.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Nup54 PF13874.6 KEG07768.1 - 8.7e-23 81.0 1.3 1.5e-22 80.2 1.3 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Mad3_BUB1_I PF08311.12 KEG07768.1 - 0.014 15.4 0.1 3.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 NRBF2 PF08961.10 KEG07768.1 - 0.043 13.4 1.4 0.091 12.4 1.1 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ABC_tran_Xtn PF12848.7 KEG07768.1 - 0.21 11.6 3.3 0.42 10.7 3.3 1.5 1 0 0 1 1 1 0 ABC transporter HPS3_N PF14761.6 KEG07769.1 - 0.0087 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 V-SNARE_C PF12352.8 KEG07771.1 - 8.6e-05 22.8 3.2 8.6e-05 22.8 3.2 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Latarcin PF10279.9 KEG07771.1 - 0.0088 16.4 0.9 0.029 14.8 0.5 2.0 2 1 0 2 2 2 1 Latarcin precursor DUF1043 PF06295.12 KEG07771.1 - 0.015 15.3 1.9 0.024 14.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FlgN PF05130.12 KEG07771.1 - 0.053 14.0 10.5 0.022 15.3 5.5 2.2 1 1 0 2 2 2 0 FlgN protein Sec20 PF03908.13 KEG07771.1 - 0.086 12.8 0.3 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 Sec20 EMP24_GP25L PF01105.24 KEG07771.1 - 1.2 9.0 3.1 2.4 8.1 0.8 2.0 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Peptidase_M14 PF00246.24 KEG07772.1 - 4e-18 66.2 0.0 1.3e-17 64.5 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KEG07772.1 - 4.9e-06 26.9 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KEG07772.1 - 7.6e-05 21.9 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SAP130_C PF16014.5 KEG07772.1 - 0.074 12.1 2.0 0.14 11.3 2.0 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Aa_trans PF01490.18 KEG07774.1 - 5.6e-66 222.9 23.7 6.7e-66 222.7 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG07774.1 - 2.4e-08 33.5 8.8 2.4e-08 33.5 8.8 2.5 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 KEG07774.1 - 0.00058 18.8 27.0 0.0051 15.7 27.0 1.9 1 1 0 1 1 1 1 Amino acid permease Shisa PF13908.6 KEG07774.1 - 1.4 9.2 2.9 97 3.1 0.5 3.4 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Kp4 PF09044.10 KEG07775.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Kp4 EDR1 PF14381.6 KEG07775.1 - 0.79 9.4 5.4 0.66 9.7 0.2 2.8 3 0 0 3 3 3 0 Ethylene-responsive protein kinase Le-CTR1 FIBP PF05427.11 KEG07777.1 - 1.4e-05 24.6 0.2 0.00078 18.8 0.1 2.8 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) DUF4123 PF13503.6 KEG07778.1 - 0.043 14.2 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Rpr2 PF04032.16 KEG07778.1 - 0.053 13.8 0.5 0.19 12.0 0.4 2.1 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3446 PF11928.8 KEG07778.1 - 3 8.2 12.6 0.65 10.3 6.7 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Glyco_transf_4 PF13439.6 KEG07779.1 - 0.17 11.9 1.3 0.41 10.6 1.3 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PCMT PF01135.19 KEG07780.1 - 9e-57 192.2 0.0 1.1e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEG07780.1 - 2.7e-10 40.3 0.0 3.8e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG07780.1 - 2.7e-08 34.4 0.0 5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEG07780.1 - 3.1e-08 33.8 0.0 6.5e-08 32.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG07780.1 - 7.2e-06 26.6 0.1 1.7e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG07780.1 - 1.2e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KEG07780.1 - 2.8e-05 25.1 0.0 7.2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEG07780.1 - 3.9e-05 23.1 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KEG07780.1 - 5.6e-05 22.3 0.0 8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KEG07780.1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 KEG07780.1 - 0.0063 16.2 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_12 PF08242.12 KEG07780.1 - 0.0077 17.0 0.0 0.02 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 KEG07780.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PrmA PF06325.13 KEG07780.1 - 0.027 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 KEG07780.1 - 0.042 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 KEG07780.1 - 0.05 13.3 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 KEG07780.1 - 0.076 13.1 0.0 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_3 PF01596.17 KEG07780.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.17 KEG07780.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Fibrillarin PF01269.17 KEG07780.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin MetW PF07021.12 KEG07780.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KEG07780.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_7 PF15963.5 KEG07781.1 - 1.6e-21 76.0 0.6 3e-21 75.1 0.6 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KEG07781.1 - 1e-07 32.0 0.4 1.9e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEG07781.1 - 0.003 17.8 0.1 0.003 17.8 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Gag_p17 PF00540.18 KEG07782.1 - 0.0028 17.6 2.7 0.51 10.3 0.5 2.7 2 0 0 2 2 2 2 gag gene protein p17 (matrix protein) Tropomyosin_1 PF12718.7 KEG07782.1 - 0.82 9.8 7.0 0.099 12.8 2.1 1.8 2 0 0 2 2 2 0 Tropomyosin like DUF4579 PF15158.6 KEG07783.1 - 0.033 13.9 1.4 0.036 13.8 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4579) SdpI PF13630.6 KEG07783.1 - 6.5 7.0 10.3 0.64 10.2 4.8 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF4456 PF14644.6 KEG07788.1 - 7.8e-24 84.5 0.0 7.8e-24 84.5 0.0 3.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4456) Filo_VP35 PF02097.15 KEG07788.1 - 0.06 12.4 0.1 0.48 9.4 0.0 2.2 2 0 0 2 2 2 0 Filoviridae VP35 ERM PF00769.19 KEG07789.1 - 1.1 9.0 34.9 0.048 13.5 23.0 2.8 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Nodulin-like PF06813.13 KEG07793.1 - 4.7e-06 26.3 5.8 4.7e-06 26.3 5.8 2.5 2 0 0 2 2 2 1 Nodulin-like BNR_6 PF15899.5 KEG07793.1 - 0.013 15.5 0.1 10 6.5 0.0 2.6 2 0 0 2 2 2 0 BNR-Asp box repeat Nodulin-like PF06813.13 KEG07794.1 - 3.6e-11 43.0 6.8 3.6e-11 43.0 6.8 2.5 2 0 0 2 2 2 1 Nodulin-like zf-CW PF07496.15 KEG07795.1 - 0.00022 21.2 8.8 0.00047 20.1 8.8 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger DUF2462 PF09495.10 KEG07795.1 - 0.012 16.3 0.6 0.012 16.3 0.6 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2462) SSP160 PF06933.11 KEG07795.1 - 0.039 12.2 4.2 0.052 11.8 4.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SPX PF03105.19 KEG07795.1 - 1.3 8.9 22.7 0.24 11.3 19.3 1.4 2 0 0 2 2 2 0 SPX domain GTP_EFTU PF00009.27 KEG07798.1 - 5.2e-52 176.2 0.1 8.9e-52 175.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEG07798.1 - 4.8e-41 139.6 0.1 1.4e-40 138.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEG07798.1 - 7.6e-16 58.3 1.6 1.4e-15 57.5 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEG07798.1 - 8.6e-05 22.6 0.1 0.0041 17.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 KEG07798.1 - 0.00024 21.1 0.0 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 KEG07798.1 - 0.0043 16.9 0.8 0.011 15.7 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 KEG07798.1 - 0.02 15.0 0.3 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain LRR_9 PF14580.6 KEG07801.1 - 0.0098 15.4 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat DUF4050 PF13259.6 KEG07801.1 - 0.063 13.6 4.8 0.24 11.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) TetR_C_13 PF16925.5 KEG07801.1 - 0.075 13.0 1.3 0.26 11.2 1.3 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SbcCD_C PF13558.6 KEG07801.1 - 0.088 13.1 0.1 0.33 11.2 0.1 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit LRR_6 PF13516.6 KEG07801.1 - 0.15 12.2 0.9 45 4.5 0.3 3.6 3 0 0 3 3 3 0 Leucine Rich repeat SUIM_assoc PF16619.5 KEG07801.1 - 0.22 11.6 26.7 1.2 9.2 0.1 4.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF5308 PF17233.2 KEG07801.1 - 0.48 10.6 6.2 0.36 11.0 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5308) PKcGMP_CC PF16808.5 KEG07802.1 - 0.0062 16.4 0.6 0.0062 16.4 0.6 3.3 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase LEA_1 PF03760.15 KEG07802.1 - 0.062 14.0 0.4 0.062 14.0 0.4 3.2 3 0 0 3 3 3 0 Late embryogenesis abundant (LEA) group 1 DUF4695 PF15766.5 KEG07802.1 - 0.49 10.6 6.6 0.11 12.7 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) Fib_alpha PF08702.10 KEG07802.1 - 9.7 6.4 9.2 4 7.6 1.7 3.0 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family SNase PF00565.17 KEG07803.1 - 1.6e-20 73.6 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SNase PF00565.17 KEG07804.1 - 1.9e-12 47.6 0.0 3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue cNMP_binding PF00027.29 KEG07808.1 - 5.1e-14 52.1 0.0 5.8e-05 23.1 0.0 4.6 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Exo_endo_phos_2 PF14529.6 KEG07810.1 - 4.5e-11 42.6 0.0 8.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Guanylate_cyc PF00211.20 KEG07812.1 - 5.6e-22 78.2 0.0 7.8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain K_channel_TID PF07941.11 KEG07813.1 - 0.0048 17.3 1.1 0.0048 17.3 1.1 3.3 3 1 0 3 3 3 2 Potassium channel Kv1.4 tandem inactivation domain SF-assemblin PF06705.11 KEG07814.1 - 0.0082 15.5 2.7 0.0082 15.5 2.7 2.0 1 1 1 2 2 2 1 SF-assemblin/beta giardin HTH_Tnp_1_2 PF13022.6 KEG07814.1 - 0.013 15.7 2.1 0.023 14.9 2.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Phage_GPO PF05929.11 KEG07814.1 - 0.083 12.5 5.3 0.12 12.0 5.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 KEG07814.1 - 0.15 12.2 6.4 0.27 11.4 6.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MetOD2 PF18548.1 KEG07814.1 - 0.2 11.8 5.2 2.7 8.2 1.6 2.3 1 1 1 2 2 2 0 Metanogen output domain 2 DUF1525 PF07511.11 KEG07814.1 - 2.7 8.2 7.2 1.8 8.8 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) DUF4763 PF15960.5 KEG07817.1 - 0.012 14.9 9.1 0.008 15.5 6.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DEAD PF00270.29 KEG07818.1 - 1.2e-48 165.2 0.0 2.9e-48 164.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG07818.1 - 4.6e-30 104.2 0.0 5e-29 100.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG07818.1 - 2.2e-06 27.8 0.0 0.00033 20.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEG07818.1 - 0.00029 20.6 0.0 0.018 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEG07818.1 - 0.0016 18.8 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain ERCC3_RAD25_C PF16203.5 KEG07818.1 - 0.0021 17.3 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Hydrolase PF00702.26 KEG07819.1 - 0.0029 17.9 0.0 0.044 14.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_tranf_2_4 PF13704.6 KEG07819.1 - 0.027 15.0 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2608 PF11019.8 KEG07819.1 - 0.035 13.6 0.1 0.37 10.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2608) EMP24_GP25L PF01105.24 KEG07820.1 - 4.2e-25 88.7 0.0 5.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HAMP PF00672.25 KEG07820.1 - 0.12 12.7 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 HAMP domain UEV PF05743.13 KEG07823.1 - 9.2e-15 54.6 0.0 5.5e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 UEV domain zf-C3HC4_3 PF13920.6 KEG07823.1 - 4e-11 42.6 7.6 9.8e-11 41.4 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG07823.1 - 6.8e-06 25.8 9.0 1.5e-05 24.7 9.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEG07823.1 - 0.00018 21.8 9.1 0.0007 19.9 9.1 2.1 1 0 0 1 1 1 1 Ring finger domain RWD PF05773.22 KEG07823.1 - 0.047 14.0 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 KEG07823.1 - 0.11 12.1 0.1 0.39 10.4 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme RNase_H PF00075.24 KEG07827.1 - 0.0001 22.5 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 RNase H zinc_ribbon_4 PF13717.6 KEG07827.1 - 0.43 10.5 3.0 1.3 9.0 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 KEG07827.1 - 0.47 10.4 3.4 1.4 8.9 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_4 PF13894.6 KEG07827.1 - 1.2 10.2 16.3 0.31 12.0 2.4 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEG07827.1 - 9.2 6.4 8.4 2.3 8.3 3.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEG07828.1 - 0.18 12.2 0.9 7.2 7.0 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KEG07828.1 - 0.23 11.1 1.9 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 KEG07828.1 - 0.32 12.0 12.1 4.3 8.4 3.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KEG07828.1 - 2.1 8.7 6.1 0.36 11.2 0.4 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KEG07828.1 - 7.6 7.2 9.7 0.51 10.9 4.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KEG07828.1 - 8.3 6.3 12.1 8.7 6.2 5.6 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type ELO PF01151.18 KEG07829.1 - 2.4e-69 233.7 20.1 2.7e-69 233.5 20.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.8 KEG07829.1 - 1.4 9.0 4.2 0.92 9.6 1.0 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0182 PF03699.13 KEG07829.1 - 2.3 6.2 9.9 2.9 5.9 9.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ELO PF01151.18 KEG07830.1 - 2.3e-80 269.8 14.8 2.7e-80 269.5 14.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 KEG07831.1 - 2e-67 227.4 9.6 2.4e-67 227.1 9.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SET PF00856.28 KEG07832.1 - 7.6e-45 153.3 1.2 4.1e-08 33.8 0.0 9.6 8 2 1 9 9 9 6 SET domain SAF PF08666.12 KEG07832.1 - 4e-07 30.6 0.0 60 4.4 0.0 8.4 9 1 0 9 9 9 0 SAF domain Urease_linker PF18473.1 KEG07832.1 - 5.5 6.9 9.1 42 4.1 0.0 4.9 5 0 0 5 5 5 0 Urease subunit beta-alpha linker domain PS_Dcarbxylase PF02666.15 KEG07833.1 - 4.2e-39 134.2 0.0 5.1e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 KEG07833.1 - 0.0079 16.4 0.1 0.72 10.1 0.0 2.5 3 0 0 3 3 3 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 KEG07833.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Atg14 PF10186.9 KEG07834.1 - 0.0063 15.6 16.9 1.7 7.6 18.4 2.4 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 KEG07834.1 - 0.052 12.5 0.1 0.052 12.5 0.1 2.1 1 1 0 2 2 2 0 LMBR1-like membrane protein AAA_13 PF13166.6 KEG07834.1 - 0.093 11.4 18.1 0.78 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF5631 PF18645.1 KEG07834.1 - 0.57 10.6 3.2 1.7 9.0 0.4 2.9 1 1 0 2 2 2 0 Family of unknown function (DUF5631) CotH PF08757.11 KEG07834.1 - 1.4 8.4 11.2 0.099 12.1 3.6 2.5 3 0 0 3 3 3 0 CotH kinase protein DUF4201 PF13870.6 KEG07834.1 - 1.9 8.2 34.8 0.5 10.1 22.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) Filament PF00038.21 KEG07834.1 - 3 7.3 33.7 0.57 9.7 26.5 2.6 1 1 0 2 2 2 0 Intermediate filament protein Seryl_tRNA_N PF02403.22 KEG07834.1 - 4 7.7 35.6 1.2 9.4 15.5 4.1 2 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KEG07834.1 - 8.4 6.5 24.8 4.5 7.3 0.3 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KEG07834.1 - 9.6 6.4 37.6 1.2 9.3 1.1 3.3 3 1 1 4 4 4 0 Tropomyosin like tRNA_bind PF01588.20 KEG07836.1 - 7.2e-27 93.4 0.0 1.4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 KEG07836.1 - 0.032 14.4 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Dynamin_N PF00350.23 KEG07837.1 - 1.4e-15 57.7 0.0 1.2e-14 54.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KEG07837.1 - 1e-07 32.0 0.0 2.6e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG07837.1 - 4.4e-05 23.5 0.0 0.032 14.1 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 KEG07837.1 - 0.00074 19.7 0.1 0.41 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.27 KEG07837.1 - 0.0051 16.4 0.6 0.09 12.3 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain SPATA1_C PF15743.5 KEG07837.1 - 0.0078 16.3 1.5 0.016 15.2 1.5 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus FeoB_N PF02421.18 KEG07837.1 - 0.023 14.2 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 KEG07837.1 - 0.033 14.7 0.0 0.26 11.8 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 KEG07837.1 - 0.038 14.2 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 KEG07838.1 - 7.2e-09 36.1 3.8 0.28 12.1 0.2 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG07838.1 - 0.0025 18.2 7.2 14 6.3 0.2 5.9 5 0 0 5 5 5 2 PQQ-like domain PQQ_2 PF13360.6 KEG07838.1 - 0.0078 15.8 0.1 0.44 10.1 0.0 2.8 2 0 0 2 2 2 1 PQQ-like domain BBS2_Mid PF14783.6 KEG07838.1 - 0.034 14.2 0.0 0.81 9.8 0.0 3.2 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region NBD_C PF17042.5 KEG07839.1 - 0.074 13.6 0.4 0.14 12.7 0.2 1.6 1 1 1 2 2 2 0 Nucleotide-binding C-terminal domain Cullin PF00888.22 KEG07843.1 - 5.4e-66 223.5 0.0 7.1e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEG07843.1 - 1.1e-14 54.2 0.1 2.3e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain PIG-H PF10181.9 KEG07844.1 - 7.6e-12 44.9 0.1 1.2e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component MerC PF03203.14 KEG07844.1 - 0.056 13.9 0.4 0.1 13.0 0.4 1.4 1 0 0 1 1 1 0 MerC mercury resistance protein ERCC4 PF02732.15 KEG07845.1 - 2.5e-13 50.5 0.0 8.6e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain RCR PF12273.8 KEG07845.1 - 0.16 12.6 0.1 0.73 10.5 0.1 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red GP67 PF17634.2 KEG07845.1 - 3.3 8.2 6.0 1.9 9.0 0.9 2.5 2 0 0 2 2 2 0 Gene product 67 O-FucT PF10250.9 KEG07848.1 - 4.9e-08 33.1 0.0 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase JAB PF01398.21 KEG07848.1 - 0.037 14.0 0.1 1.4 8.9 0.3 2.3 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pdase_M17_N2 PF18295.1 KEG07851.1 - 0.03 14.6 1.1 0.13 12.5 0.7 2.1 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 Dcc1 PF09724.9 KEG07852.1 - 1.5e-50 172.4 0.0 1.7e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 ubiquitin PF00240.23 KEG07853.1 - 0.0013 18.4 0.1 0.75 9.6 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family BAG PF02179.16 KEG07853.1 - 0.0013 19.1 2.6 0.0033 17.8 2.6 1.6 1 0 0 1 1 1 1 BAG domain Nic96 PF04097.14 KEG07855.1 - 3.9e-43 147.9 0.0 1.3e-42 146.1 0.0 1.7 1 1 0 1 1 1 1 Nup93/Nic96 TPR_4 PF07721.14 KEG07855.1 - 4 8.3 9.2 13 6.7 4.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAPc_SNAP43 PF09808.9 KEG07856.1 - 6.7e-07 29.4 0.0 9.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.29 KEG07857.1 - 6.3e-28 97.7 0.0 1.5e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG07857.1 - 3.1e-21 75.8 0.0 4.3e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AOX PF01786.17 KEG07858.1 - 6.5e-95 316.8 1.1 6.9e-66 221.9 0.3 2.2 1 1 1 2 2 2 2 Alternative oxidase BKACE PF05853.12 KEG07858.1 - 0.038 13.3 0.3 1.7 7.9 0.0 2.3 2 1 0 2 2 2 0 beta-keto acid cleavage enzyme HSP90 PF00183.18 KEG07859.1 - 3.2e-229 762.1 25.9 4e-229 761.8 25.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KEG07859.1 - 8.5e-16 58.5 0.0 1.7e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEG07859.1 - 3.1e-10 40.0 0.1 9e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAR1 PF03101.15 KEG07859.1 - 0.021 15.5 0.9 0.093 13.4 0.3 2.3 2 0 0 2 2 2 0 FAR1 DNA-binding domain LOH1CR12 PF10158.9 KEG07859.1 - 0.06 13.4 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 Tumour suppressor protein ABC_tran PF00005.27 KEG07860.1 - 5.3e-43 146.8 1.8 1.9e-20 73.8 0.0 3.8 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 KEG07860.1 - 6.8e-17 62.2 3.4 8e-05 22.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG07860.1 - 8.3e-14 51.6 0.5 4e-05 23.2 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEG07860.1 - 1.5e-07 31.5 0.4 0.0045 16.9 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KEG07860.1 - 2.1e-06 27.4 0.2 0.068 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEG07860.1 - 0.00018 21.8 0.0 0.18 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEG07860.1 - 0.00063 19.8 0.5 0.061 13.4 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG07860.1 - 0.00075 19.9 0.0 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KEG07860.1 - 0.0023 18.2 0.4 2.5 8.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KEG07860.1 - 0.003 17.9 0.0 0.75 10.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ABC_tran_Xtn PF12848.7 KEG07860.1 - 0.0061 16.6 0.5 0.0061 16.6 0.5 3.6 3 1 0 3 3 2 1 ABC transporter AAA_23 PF13476.6 KEG07860.1 - 0.0069 16.9 0.1 0.13 12.8 0.0 5.1 4 1 1 5 5 5 2 AAA domain Rad17 PF03215.15 KEG07860.1 - 0.0085 16.0 0.7 3.2 7.6 0.0 3.0 3 0 0 3 3 3 1 Rad17 P-loop domain SbcCD_C PF13558.6 KEG07860.1 - 0.012 15.8 1.2 1.3 9.3 0.1 4.2 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KEG07860.1 - 0.014 15.8 0.2 12 6.3 0.3 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEG07860.1 - 0.022 14.8 0.1 7.3 6.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEG07860.1 - 0.027 14.4 0.2 0.49 10.3 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KEG07860.1 - 0.042 14.0 1.4 3 8.0 0.0 3.4 4 1 0 4 4 3 0 AAA domain AAA_24 PF13479.6 KEG07860.1 - 0.044 13.5 4.5 0.87 9.3 0.0 3.4 3 1 0 4 4 4 0 AAA domain T2SSE PF00437.20 KEG07860.1 - 0.064 12.3 0.0 5.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Hemerythrin PF01814.23 KEG07860.1 - 0.092 13.4 6.1 0.58 10.8 0.0 3.6 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain AAA_15 PF13175.6 KEG07860.1 - 1.1 8.9 13.5 0.84 9.3 0.1 4.2 5 1 0 5 5 3 0 AAA ATPase domain AAA_18 PF13238.6 KEG07860.1 - 2.5 8.6 8.8 3.7 8.1 0.0 3.8 4 1 1 5 5 3 0 AAA domain Pkinase PF00069.25 KEG07861.1 - 1.6e-48 165.4 0.0 7.7e-37 127.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07861.1 - 2.2e-28 99.2 0.7 1.9e-17 63.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG07861.1 - 0.0041 16.0 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Galactosyl_T PF01762.21 KEG07863.1 - 2.9e-05 24.0 0.0 0.0024 17.7 0.0 2.7 2 1 0 2 2 2 2 Galactosyltransferase DUF1380 PF07128.12 KEG07863.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Peptidase_C2 PF00648.21 KEG07864.1 - 1.1e-34 119.8 0.0 1.9e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG07864.1 - 1.2e-09 38.4 0.3 3.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Ras PF00071.22 KEG07865.1 - 8.1e-17 61.3 0.0 9.6e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KEG07865.1 - 5.6e-05 22.7 0.0 7.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG07865.1 - 0.00014 22.1 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KEG07865.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-RanBP PF00641.18 KEG07866.1 - 9.5e-19 66.4 62.3 1.2e-06 27.7 1.9 7.4 8 0 0 8 8 8 5 Zn-finger in Ran binding protein and others FYVE PF01363.21 KEG07866.1 - 1.3e-17 63.7 12.4 1.3e-17 63.7 12.4 4.4 3 2 0 3 3 3 1 FYVE zinc finger Vps36-NZF-N PF16988.5 KEG07866.1 - 0.0047 16.3 43.0 0.14 11.6 1.2 6.6 7 0 0 7 7 7 5 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KEG07866.1 - 0.081 13.0 0.4 0.081 13.0 0.4 9.0 8 3 2 10 10 10 0 Sec23/Sec24 zinc finger DZR PF12773.7 KEG07866.1 - 2 8.5 58.2 1.6 8.8 1.5 6.0 1 1 7 8 8 8 0 Double zinc ribbon Ribosomal_S27e PF01667.17 KEG07867.1 - 4.6e-23 80.7 4.1 5.6e-23 80.4 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KEG07867.1 - 0.004 16.6 1.1 0.006 16.1 1.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 KEG07867.1 - 0.0062 16.7 0.8 0.0083 16.3 0.8 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 KEG07867.1 - 0.0066 16.3 2.0 0.11 12.4 2.0 2.4 1 1 0 1 1 1 1 zinc-ribbon domain zf-HIT PF04438.16 KEG07867.1 - 0.69 9.8 6.0 2.7 7.9 0.3 2.6 3 0 0 3 3 3 0 HIT zinc finger Dpy-30 PF05186.13 KEG07868.1 - 1.6e-14 53.3 1.1 2.4e-14 52.8 1.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 KEG07868.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Peptidase_M41 PF01434.18 KEG07869.1 - 1.1e-39 136.3 3.6 1.8e-39 135.6 3.6 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEG07869.1 - 2.1e-39 134.9 0.0 4.8e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG07869.1 - 4.6e-05 23.9 0.3 0.00021 21.7 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 KEG07869.1 - 0.00026 20.7 0.1 0.00067 19.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KEG07869.1 - 0.0006 20.1 0.9 0.0063 16.8 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEG07869.1 - 0.0018 18.3 0.1 0.01 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KEG07869.1 - 0.0031 16.8 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KEG07869.1 - 0.0063 16.6 2.6 0.01 16.0 0.3 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KEG07869.1 - 0.014 15.1 0.0 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KEG07869.1 - 0.045 13.4 1.0 0.18 11.5 0.0 2.4 2 1 1 3 3 3 0 Sigma-54 interaction domain Peptidase_M50B PF13398.6 KEG07869.1 - 0.058 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ATPase PF06745.13 KEG07869.1 - 0.083 12.2 1.1 0.24 10.7 0.1 2.1 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.9 KEG07869.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KEG07869.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KEG07869.1 - 0.13 12.2 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Cupin_8 PF13621.6 KEG07870.1 - 2.3e-13 50.5 0.1 4.8e-10 39.6 0.0 2.1 1 1 1 2 2 2 2 Cupin-like domain DUF1779 PF08680.10 KEG07870.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 TATA-box binding DUF2201_N PF13203.6 KEG07870.1 - 0.14 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Cupin_8 PF13621.6 KEG07871.1 - 1.1e-54 185.9 0.1 1.2e-54 185.7 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KEG07871.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Utp12 PF04003.12 KEG07872.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Aa_trans PF01490.18 KEG07874.1 - 2.9e-45 154.7 33.5 3.3e-45 154.5 33.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG07874.1 - 3.3e-11 42.8 11.2 3.3e-11 42.8 11.2 2.2 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 KEG07874.1 - 1.3e-06 27.5 24.0 1.3e-06 27.5 24.0 2.2 1 1 1 2 2 2 1 Amino acid permease Galactosyl_T PF01762.21 KEG07875.1 - 0.059 13.2 0.0 0.26 11.1 0.0 2.1 3 0 0 3 3 3 0 Galactosyltransferase CPT_N PF16484.5 KEG07876.1 - 0.0016 18.4 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 1 Carnitine O-palmitoyltransferase N-terminus DUF3173 PF11372.8 KEG07876.1 - 0.0078 16.1 0.1 5 7.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3173) DUF1751 PF08551.10 KEG07876.1 - 0.039 14.5 0.1 0.22 12.1 0.0 2.3 2 1 2 4 4 4 0 Eukaryotic integral membrane protein (DUF1751) TisB_toxin PF13939.6 KEG07876.1 - 0.82 9.5 2.7 28 4.6 0.2 2.5 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system Galactosyl_T PF01762.21 KEG07877.1 - 2e-05 24.5 0.0 0.76 9.6 0.0 3.8 3 1 0 4 4 4 3 Galactosyltransferase RuvC_1 PF18516.1 KEG07877.1 - 0.26 10.4 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 RuvC nuclease domain DUF4588 PF15251.6 KEG07878.1 - 0.25 11.1 0.0 0.31 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Ribosomal_L31e PF01198.19 KEG07879.1 - 4.2e-26 91.0 1.3 4.2e-26 91.0 1.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L31e Pex19 PF04614.12 KEG07881.1 - 4.6e-17 62.6 5.7 2.3e-14 53.8 0.0 3.2 1 1 1 3 3 3 2 Pex19 protein family AAA PF00004.29 KEG07882.1 - 2.6e-17 63.5 0.0 4.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KEG07882.1 - 3.3e-13 49.8 0.0 7.2e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KEG07882.1 - 2.4e-11 43.7 0.0 9.9e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KEG07882.1 - 2.6e-08 34.0 0.0 7e-08 32.6 0.0 1.7 2 1 0 2 2 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KEG07882.1 - 3e-07 30.8 0.0 8.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEG07882.1 - 4.4e-07 30.0 0.0 3.8e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG07882.1 - 4.4e-07 30.4 0.0 7.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KEG07882.1 - 7.6e-07 29.0 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEG07882.1 - 1e-05 25.6 0.0 0.00012 22.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KEG07882.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG07882.1 - 5e-05 23.7 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEG07882.1 - 0.00013 21.9 2.4 0.0046 16.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KEG07882.1 - 0.00027 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KEG07882.1 - 0.0029 17.3 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEG07882.1 - 0.0042 17.2 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEG07882.1 - 0.0057 16.1 0.0 0.017 14.5 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEG07882.1 - 0.0058 16.5 0.0 0.033 14.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KEG07882.1 - 0.0077 15.7 0.0 0.043 13.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial TniB protein Sigma54_activat PF00158.26 KEG07882.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 KEG07882.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 KEG07882.1 - 0.011 16.1 0.0 0.064 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA C-terminal domain AAA_28 PF13521.6 KEG07882.1 - 0.015 15.5 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KEG07882.1 - 0.021 14.8 0.0 1.3 9.0 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Aminotran_5 PF00266.19 KEG07882.1 - 0.022 13.7 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V T2SSE PF00437.20 KEG07882.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KEG07882.1 - 0.03 14.1 0.3 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.6 KEG07882.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 KEG07882.1 - 0.034 13.1 0.1 0.5 9.3 0.1 2.2 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KEG07882.1 - 0.034 14.6 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG07882.1 - 0.04 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KEG07882.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KEG07882.1 - 0.098 13.1 0.0 0.25 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KEG07882.1 - 0.16 11.5 1.7 3 7.4 1.7 2.2 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEG07882.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NAD_binding_8 PF13450.6 KEG07882.1 - 0.3 11.4 1.6 3.8 7.8 0.1 2.8 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain SNAPc19 PF15497.6 KEG07883.1 - 0.0061 17.0 8.7 0.0061 17.0 8.7 3.7 3 2 0 3 3 3 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 MitMem_reg PF13012.6 KEG07883.1 - 0.32 11.4 4.5 13 6.3 4.5 3.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Baculo_PEP_C PF04513.12 KEG07883.1 - 2 8.5 7.3 3.5 7.7 0.4 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2222 PF09984.9 KEG07884.1 - 0.14 12.0 0.5 2.2 8.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) SNF2_N PF00176.23 KEG07885.1 - 4.2e-36 124.4 0.5 1.1e-35 123.0 0.1 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG07885.1 - 5.8e-10 39.5 0.0 2.5e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG07885.1 - 0.00087 19.3 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KEG07885.1 - 0.0048 16.1 0.0 0.016 14.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KEG07885.1 - 0.016 14.8 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF2271 PF10029.9 KEG07885.1 - 0.11 12.1 0.0 17 5.1 0.1 2.5 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) AAA_22 PF13401.6 KEG07885.1 - 0.13 12.5 0.0 0.62 10.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain Orthopox_F8 PF05886.11 KEG07887.1 - 1.6 8.9 7.9 7.1 6.8 0.1 3.1 2 0 0 2 2 2 0 Orthopoxvirus F8 protein eIF-1a PF01176.19 KEG07888.1 - 2e-11 43.5 0.0 4.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L17 PF01196.19 KEG07891.1 - 1.9e-11 44.7 0.0 2.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Peripla_BP_6 PF13458.6 KEG07896.1 - 3.3e-09 36.9 0.0 0.00035 20.3 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.20 KEG07896.1 - 2.2e-05 24.1 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3481 PF11980.8 KEG07896.1 - 0.13 11.9 1.6 1.6 8.5 0.0 2.8 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein Ion_trans_2 PF07885.16 KEG07897.1 - 1.3e-10 41.1 2.7 1.3e-10 41.1 2.7 2.0 2 0 0 2 2 2 1 Ion channel DUF1930 PF09122.10 KEG07899.1 - 3.8e-25 87.7 0.1 6.8e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.20 KEG07899.1 - 1.8e-13 50.9 0.0 1.3e-08 35.3 0.0 2.7 2 1 0 2 2 2 2 Rhodanese-like domain PT-VENN PF04829.13 KEG07902.1 - 0.0081 16.2 0.7 0.019 15.0 0.7 1.6 1 0 0 1 1 1 1 Pre-toxin domain with VENN motif DNA_ligase_OB_2 PF14743.6 KEG07904.1 - 3.2e-19 68.7 0.1 5.5e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KEG07904.1 - 2.4e-16 60.0 0.0 5e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DUF4379 PF14311.6 KEG07904.1 - 2.2e-11 44.0 1.6 4.5e-11 42.9 1.6 1.6 1 0 0 1 1 1 1 Probable Zinc-ribbon domain mRNA_cap_enzyme PF01331.19 KEG07904.1 - 0.006 16.4 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain Zn_ribbon_SprT PF17283.2 KEG07904.1 - 0.017 15.0 7.4 0.12 12.3 7.4 2.3 1 1 0 1 1 1 0 SprT-like zinc ribbon domain HypA PF01155.19 KEG07904.1 - 0.091 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_ligase_OB_2 PF14743.6 KEG07905.1 - 2.7e-19 68.9 0.0 5e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KEG07905.1 - 6.1e-17 61.9 0.0 1.8e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF4379 PF14311.6 KEG07905.1 - 3.8e-05 24.0 5.1 7.8e-05 23.0 4.4 2.0 2 0 0 2 2 2 1 Probable Zinc-ribbon domain mRNA_cap_enzyme PF01331.19 KEG07905.1 - 0.0041 17.0 0.0 0.17 11.7 0.0 2.8 3 1 0 3 3 3 1 mRNA capping enzyme, catalytic domain FlhC PF05280.11 KEG07905.1 - 0.039 13.7 1.2 0.096 12.4 1.2 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Zn-ribbon_8 PF09723.10 KEG07905.1 - 0.23 11.6 1.0 0.77 9.9 1.0 2.0 1 0 0 1 1 1 0 Zinc ribbon domain DUF1631 PF07793.11 KEG07905.1 - 0.73 8.2 2.7 0.33 9.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) DUF4763 PF15960.5 KEG07907.1 - 0.004 16.5 0.5 0.0055 16.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) TMF_TATA_bd PF12325.8 KEG07907.1 - 0.0076 16.5 0.2 0.014 15.6 0.2 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KEG07907.1 - 0.011 15.4 1.4 0.021 14.6 1.4 1.5 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.8 KEG07907.1 - 0.014 15.5 3.2 0.02 15.0 3.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tektin PF03148.14 KEG07907.1 - 0.017 13.9 1.4 0.023 13.5 1.4 1.2 1 0 0 1 1 1 0 Tektin family Chibby PF14645.6 KEG07907.1 - 0.027 14.9 0.3 0.041 14.3 0.3 1.3 1 0 0 1 1 1 0 Chibby family TolA_bind_tri PF16331.5 KEG07907.1 - 0.033 14.3 2.9 0.071 13.2 2.9 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 KEG07907.1 - 0.039 14.0 0.3 0.055 13.5 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KEG07907.1 - 0.047 13.0 2.8 0.066 12.5 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KEG07907.1 - 0.074 13.5 0.3 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) LPP PF04728.13 KEG07907.1 - 0.099 13.0 1.0 0.18 12.2 1.0 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Uso1_p115_C PF04871.13 KEG07907.1 - 0.12 12.7 0.8 0.19 12.1 0.2 1.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Poty_PP PF08440.10 KEG07907.1 - 0.13 11.3 0.4 0.18 10.9 0.4 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein TFCD_C PF12612.8 KEG07910.1 - 1.1e-32 113.5 0.3 2.9e-32 112.0 0.4 1.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal PI3_PI4_kinase PF00454.27 KEG07911.1 - 9.4e-48 163.2 0.0 4e-32 112.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KEG07911.1 - 6.1e-39 133.3 0.6 1.1e-38 132.5 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KEG07911.1 - 1e-10 41.7 0.0 9.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KEG07911.1 - 0.0088 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) APO_RNA-bind PF05634.11 KEG07911.1 - 0.13 11.6 0.1 0.35 10.2 0.1 1.6 1 0 0 1 1 1 0 APO RNA-binding PCIF1_WW PF12237.8 KEG07912.1 - 1.4e-12 47.5 0.1 2.5e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Lysine_decarbox PF03641.14 KEG07914.1 - 6.7e-07 29.5 0.0 8.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase Thioredoxin_7 PF13899.6 KEG07915.1 - 2.9e-08 33.8 0.1 6.8e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KEG07915.1 - 4.2e-06 26.9 0.0 7.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Imm70 PF15601.6 KEG07916.1 - 0.058 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 70 Trypsin_2 PF13365.6 KEG07916.1 - 0.075 13.9 0.0 0.18 12.7 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain Thioredoxin PF00085.20 KEG07921.1 - 1.9e-09 37.4 0.3 2.7e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KEG07921.1 - 0.0014 18.9 0.8 0.0052 17.1 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like M16C_assoc PF08367.11 KEG07921.1 - 0.059 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated DIM1 PF02966.16 KEG07921.1 - 0.07 12.9 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Ribosomal_L29 PF00831.23 KEG07921.1 - 0.19 11.7 1.6 4.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein Sensor PF13796.6 KEG07922.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative sensor CCDC106 PF15794.5 KEG07922.1 - 1.3 8.7 3.8 1.6 8.4 0.0 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 MFS_1_like PF12832.7 KEG07923.1 - 6.6e-53 180.0 28.7 9.5e-53 179.4 28.7 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KEG07923.1 - 2.2e-18 66.3 49.0 4.5e-12 45.6 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KEG07923.1 - 6.3e-11 41.9 24.0 8.6e-11 41.4 24.0 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KEG07923.1 - 0.00022 20.1 23.0 0.00042 19.2 23.0 1.3 1 1 0 1 1 1 1 LacY proton/sugar symporter Solute_trans_a PF03619.16 KEG07924.1 - 4.5e-77 259.2 15.0 5.6e-77 258.8 15.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.6 KEG07924.1 - 0.0081 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 2 Skp1 PF01466.19 KEG07925.1 - 6.6e-25 87.0 1.6 1.1e-24 86.2 1.6 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KEG07925.1 - 5.2e-15 55.4 0.0 2.7e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PPR_2 PF13041.6 KEG07927.1 - 9.7e-15 54.5 0.0 1.6e-06 28.2 0.0 3.8 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.6 KEG07927.1 - 5.9e-09 35.9 0.1 0.00037 20.5 0.0 3.7 3 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KEG07927.1 - 3.5e-06 26.5 2.6 0.00025 20.5 0.1 3.5 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KEG07927.1 - 3.8e-05 23.7 3.0 0.43 10.9 0.0 6.0 6 1 0 6 6 6 1 PPR repeat PPR_1 PF12854.7 KEG07927.1 - 9.1e-05 22.1 0.9 2.3 8.0 0.0 4.8 4 1 0 4 4 4 1 PPR repeat Cullin PF00888.22 KEG07927.1 - 0.067 11.8 0.7 0.099 11.2 0.7 1.2 1 0 0 1 1 1 0 Cullin family Pkinase PF00069.25 KEG07928.1 - 1.6e-58 198.1 0.0 2.8e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07928.1 - 2e-41 142.0 0.0 1.4e-27 96.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_MLP1_2 PF07926.12 KEG07932.1 - 0.0014 18.7 7.8 0.0014 18.7 7.8 6.2 3 2 1 5 5 5 2 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KEG07932.1 - 0.015 15.6 5.4 0.015 15.6 5.4 6.3 4 2 2 6 6 6 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KEG07932.1 - 0.027 13.8 73.4 0.025 14.0 8.0 4.7 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding Pro_isomerase PF00160.21 KEG07933.1 - 2.8e-26 92.7 0.0 3.5e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.21 KEG07934.1 - 5e-26 90.8 38.3 1.2e-16 60.7 16.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 KEG07934.1 - 3.9 5.8 9.7 2.6 6.4 1.9 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.6 KEG07934.1 - 7.5 6.9 19.0 1.2 9.5 7.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Abhydrolase_6 PF12697.7 KEG07935.1 - 1.2e-18 68.5 1.2 1.6e-18 68.1 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEG07935.1 - 2.3e-13 50.4 0.1 5.6e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG07935.1 - 1.6e-12 47.3 0.2 4e-12 45.9 0.0 1.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KEG07935.1 - 0.02 14.8 0.0 0.17 11.7 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KEG07935.1 - 0.038 14.1 0.8 0.13 12.3 0.8 1.8 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KEG07935.1 - 0.045 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 KEG07935.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase ATPase_gene1 PF09527.10 KEG07935.1 - 5.8 7.2 7.1 0.16 12.2 0.8 1.6 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter LRR_6 PF13516.6 KEG07936.1 - 8.5e-16 56.6 23.4 0.0045 16.9 0.0 9.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 KEG07936.1 - 5.7e-05 23.4 7.9 1.5 9.4 0.0 5.3 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG07936.1 - 0.0011 18.7 14.2 0.074 12.8 0.2 7.4 5 2 2 7 7 7 1 Leucine rich repeat LRR_1 PF00560.33 KEG07936.1 - 0.0029 17.9 0.2 38 5.4 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich Repeat cNMP_binding PF00027.29 KEG07937.1 - 2.1e-09 37.3 0.7 2.5e-06 27.5 0.1 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Atg14 PF10186.9 KEG07938.1 - 0.003 16.7 3.0 0.004 16.3 3.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1654 PF07867.11 KEG07938.1 - 0.034 13.9 0.3 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DUF4618 PF15397.6 KEG07938.1 - 0.059 12.8 1.5 0.084 12.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ZapB PF06005.12 KEG07938.1 - 0.38 11.2 3.5 5 7.6 0.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB FliJ PF02050.16 KEG07940.1 - 0.014 15.6 9.3 0.014 15.6 9.3 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 KEG07940.1 - 0.09 12.1 15.2 12 5.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM83 PF07894.12 KEG07940.1 - 0.29 10.6 2.4 0.36 10.3 0.1 1.9 2 0 0 2 2 2 0 FAM83 A-H GAGA_bind PF06217.12 KEG07940.1 - 1.1 9.5 6.4 1.4 9.1 6.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Mucin PF01456.17 KEG07940.1 - 3.6 7.6 10.8 19 5.2 10.6 2.2 1 1 0 1 1 1 0 Mucin-like glycoprotein GARP PF16731.5 KEG07941.1 - 0.013 15.2 15.8 0.013 15.2 15.8 4.9 2 1 3 5 5 5 0 Glutamic acid/alanine-rich protein of Trypanosoma CorA PF01544.18 KEG07941.1 - 0.43 9.9 2.7 0.74 9.1 2.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Leu_zip PF15294.6 KEG07941.1 - 3 7.3 16.8 0.83 9.1 12.7 1.9 1 1 1 2 2 2 0 Leucine zipper Mucin PF01456.17 KEG07943.1 - 0.0076 16.2 11.6 0.0076 16.2 11.6 3.7 1 1 2 3 3 2 1 Mucin-like glycoprotein dCache_2 PF08269.11 KEG07943.1 - 0.0082 15.4 3.2 0.0082 15.4 3.2 2.2 2 0 0 2 2 2 1 Cache domain Hrs_helical PF12210.8 KEG07943.1 - 0.19 12.3 3.6 0.85 10.2 0.0 3.2 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF2514 PF10721.9 KEG07943.1 - 0.2 11.7 43.4 0.99 9.4 13.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2514) HisKA_2 PF07568.12 KEG07943.1 - 0.34 11.0 1.4 15 5.7 0.1 2.8 1 1 1 2 2 2 0 Histidine kinase DUF1664 PF07889.12 KEG07943.1 - 0.42 10.7 12.7 0.15 12.1 1.2 3.4 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) WBP-1 PF11669.8 KEG07943.1 - 1.1 9.9 3.0 14 6.4 0.0 2.9 3 0 0 3 3 3 0 WW domain-binding protein 1 GARP PF16731.5 KEG07943.1 - 1.4 8.6 58.4 0.32 10.6 22.4 2.3 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma FliJ PF02050.16 KEG07943.1 - 1.8 8.8 17.9 1.1 9.4 0.7 3.6 2 1 0 3 3 3 0 Flagellar FliJ protein Lebercilin PF15619.6 KEG07943.1 - 4.6 6.9 20.3 4.6 6.8 7.3 3.0 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin-6_N PF09177.11 KEG07943.1 - 4.7 7.8 14.7 1.6 9.3 2.5 3.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 KEG07943.1 - 7.5 7.1 10.5 1.1 9.8 1.6 2.9 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 KEG07943.1 - 7.8 6.9 14.4 0.47 10.8 1.2 3.4 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KEG07943.1 - 9.7 6.4 14.1 12 6.1 1.9 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_S9_N PF02897.15 KEG07945.1 - 2.6e-38 131.9 0.0 1.4e-37 129.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain ACP_syn_III PF08545.10 KEG07945.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Secretin_N_2 PF07655.13 KEG07945.1 - 4.3 8.0 9.7 25 5.5 8.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_S9 PF00326.21 KEG07946.1 - 9.1e-47 159.3 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEG07946.1 - 0.00045 19.9 0.2 0.0014 18.3 0.2 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KEG07946.1 - 0.011 15.6 0.6 0.024 14.5 0.6 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG07946.1 - 0.038 13.3 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-C3HC4_2 PF13923.6 KEG07948.1 - 1.4e-07 31.2 7.2 2.2e-07 30.6 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG07948.1 - 2.2e-06 27.5 3.9 3.6e-06 26.8 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEG07948.1 - 3.2e-06 26.9 2.2 5.2e-06 26.2 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEG07948.1 - 6.9e-06 26.1 8.8 1.1e-05 25.4 8.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KEG07948.1 - 1.3e-05 25.0 3.6 2.2e-05 24.3 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG07948.1 - 2.8e-05 23.9 5.0 4.9e-05 23.1 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ndc1_Nup PF09531.10 KEG07948.1 - 0.00025 19.9 16.0 0.00028 19.7 16.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-RING_2 PF13639.6 KEG07948.1 - 0.00028 21.2 6.6 0.00044 20.5 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEG07948.1 - 0.0007 19.6 9.3 0.0015 18.5 9.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KEG07948.1 - 0.0087 16.2 1.4 0.016 15.3 1.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KEG07948.1 - 0.021 14.6 1.5 0.04 13.7 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Presenilin PF01080.17 KEG07948.1 - 0.039 12.7 16.2 0.048 12.4 16.2 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 KEG07948.1 - 0.21 11.6 30.1 0.29 11.1 30.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_6 PF14835.6 KEG07948.1 - 0.36 10.7 4.4 1 9.3 4.4 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein SOG2 PF10428.9 KEG07948.1 - 0.41 9.8 31.1 0.6 9.2 31.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TF_Zn_Ribbon PF08271.12 KEG07948.1 - 0.6 9.7 3.6 3.8 7.1 0.6 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3H2C3 PF17122.5 KEG07948.1 - 2.7 8.1 5.7 7.5 6.7 5.7 1.7 1 1 0 1 1 1 0 Zinc-finger PAT1 PF09770.9 KEG07948.1 - 3 6.0 32.1 3.9 5.6 32.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 KEG07948.1 - 3.9 5.9 9.8 4.6 5.6 9.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Metallophos PF00149.28 KEG07954.1 - 7.6e-12 46.2 0.1 1.1e-11 45.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEG07954.1 - 0.00022 21.5 0.0 0.00046 20.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_8 PF13621.6 KEG07956.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain Aldose_epim PF01263.20 KEG07957.1 - 1.3e-55 188.9 0.0 1.6e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Surface_antigen PF11054.8 KEG07957.1 - 0.0038 17.0 0.1 0.0068 16.1 0.1 1.3 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Spt20 PF12090.8 KEG07958.1 - 1.6 8.3 8.0 2 8.0 4.4 2.1 2 0 0 2 2 2 0 Spt20 family Ribosomal_L2 PF00181.23 KEG07960.1 - 1.1e-11 44.5 0.1 1.8e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_1 PF00515.28 KEG07961.1 - 3.7e-16 58.2 10.9 1.1e-06 28.2 0.3 5.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG07961.1 - 5.6e-16 57.3 12.7 4.4e-05 23.3 0.2 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG07961.1 - 9.8e-15 54.0 10.5 4.3e-05 23.1 0.2 5.8 4 2 2 6 6 6 2 TPR repeat TPR_17 PF13431.6 KEG07961.1 - 1.1e-12 47.3 16.6 0.00044 20.4 1.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEG07961.1 - 1.5e-09 37.3 5.4 0.013 15.6 0.0 4.9 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEG07961.1 - 5.8e-09 36.4 23.6 1.4e-06 28.9 1.2 5.8 3 2 2 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEG07961.1 - 1.9e-08 34.7 19.3 0.00026 21.4 0.9 5.9 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG07961.1 - 1.8e-07 31.4 28.7 0.0023 18.6 0.0 8.1 6 2 4 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEG07961.1 - 3e-05 24.2 7.2 0.00039 20.7 0.5 4.8 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KEG07961.1 - 4.2e-05 23.6 11.7 0.034 14.3 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG07961.1 - 7.5e-05 23.1 4.2 0.9 10.3 1.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG07961.1 - 0.0022 17.9 2.6 0.88 9.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG07961.1 - 0.021 14.9 2.3 52 4.0 0.0 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KEG07961.1 - 0.14 11.1 0.9 0.58 9.1 0.1 2.1 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KEG07961.1 - 0.8 9.7 13.3 1.8 8.6 1.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEG07961.1 - 1.1 9.7 20.0 2.7 8.4 0.7 4.7 4 1 0 5 5 4 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.25 KEG07962.1 - 1.9e-29 102.9 0.0 8.6e-26 91.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEG07962.1 - 1.8e-16 60.0 0.1 4.7e-16 58.7 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KEG07962.1 - 9e-14 51.3 0.0 1.4e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KEG07962.1 - 3.8e-10 39.7 0.0 6.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF5304 PF17230.2 KEG07963.1 - 0.085 13.1 4.3 0.049 13.9 2.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5304) DUF4457 PF14652.6 KEG07964.1 - 2.5e-28 99.3 0.0 7.2e-10 38.6 0.0 5.2 4 2 0 4 4 4 4 Domain of unknown function (DUF4457) TRAM_LAG1_CLN8 PF03798.16 KEG07965.1 - 8.2e-22 77.9 15.3 8.2e-22 77.9 15.3 1.6 2 0 0 2 2 2 1 TLC domain HEAT_2 PF13646.6 KEG07966.1 - 5.7e-06 26.6 0.2 7.5e-06 26.2 0.2 1.3 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KEG07966.1 - 0.00099 19.2 0.1 0.99 9.8 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat HEAT_PBS PF03130.16 KEG07966.1 - 0.0012 19.3 0.5 0.0041 17.7 0.1 2.0 2 1 0 2 2 2 1 PBS lyase HEAT-like repeat Peptidase_M56 PF05569.11 KEG07967.1 - 0.0049 16.1 0.0 0.0058 15.9 0.0 1.0 1 0 0 1 1 1 1 BlaR1 peptidase M56 TMEM52 PF14979.6 KEG07967.1 - 0.017 15.1 1.7 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Transmembrane 52 zf-LITAF-like PF10601.9 KEG07967.1 - 0.024 14.9 3.2 0.052 13.8 0.3 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain SPW PF03779.14 KEG07967.1 - 0.041 13.5 1.2 0.065 12.8 1.2 1.3 1 0 0 1 1 1 0 SPW repeat TMEM223 PF14640.6 KEG07967.1 - 0.045 13.9 0.1 0.7 10.1 0.0 2.0 1 1 1 2 2 2 0 Transmembrane protein 223 ERGIC_N PF13850.6 KEG07967.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Shisa PF13908.6 KEG07967.1 - 3.4 7.9 7.8 1.8 8.7 2.2 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PUF PF00806.19 KEG07968.1 - 9e-53 173.1 3.8 1.1e-06 28.0 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 KEG07968.1 - 0.0066 16.8 0.8 3.9 7.8 0.0 3.8 3 2 1 4 4 4 1 CPL (NUC119) domain sCache_2 PF17200.4 KEG07968.1 - 0.096 12.5 0.1 33 4.3 0.0 3.6 3 1 1 4 4 4 0 Single Cache domain 2 Sacchrp_dh_NADP PF03435.18 KEG07968.1 - 0.1 12.9 0.2 3.2 8.0 0.0 2.6 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Mif2_N PF15624.6 KEG07968.1 - 4.4 8.0 9.5 0.081 13.6 2.1 1.9 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ax_dynein_light PF10211.9 KEG07969.1 - 1.7e-48 165.1 6.4 1.9e-48 164.9 6.4 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Lipoprotein_22 PF17294.2 KEG07969.1 - 0.025 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised lipoprotein family ANAPC8 PF04049.13 KEG07969.1 - 0.068 13.2 0.2 0.1 12.6 0.2 1.4 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 APG6_N PF17675.1 KEG07969.1 - 0.18 12.3 7.9 0.35 11.4 7.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region PPR_2 PF13041.6 KEG07971.1 - 2.1e-05 24.6 0.0 0.0027 17.9 0.0 2.8 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 KEG07971.1 - 0.00077 19.5 0.0 23 5.5 0.0 3.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 KEG07971.1 - 0.045 13.8 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain AAA PF00004.29 KEG07974.1 - 1.1e-42 145.6 0.0 2.2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG07974.1 - 3.9e-10 39.4 0.1 8.5e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KEG07974.1 - 3.4e-06 27.1 0.2 5.3e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEG07974.1 - 7.8e-06 26.1 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEG07974.1 - 1.1e-05 25.7 0.0 0.0059 16.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG07974.1 - 3.5e-05 24.3 0.3 0.00095 19.6 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEG07974.1 - 0.00023 20.9 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KEG07974.1 - 0.00057 19.1 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KEG07974.1 - 0.0019 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG07974.1 - 0.0059 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEG07974.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 KEG07974.1 - 0.008 16.1 0.1 0.38 10.6 0.0 2.4 2 1 1 3 3 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KEG07974.1 - 0.0085 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KEG07974.1 - 0.0097 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KEG07974.1 - 0.0098 15.3 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEG07974.1 - 0.0099 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KEG07974.1 - 0.011 16.3 0.0 0.032 14.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEG07974.1 - 0.017 14.9 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KEG07974.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEG07974.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KEG07974.1 - 0.039 13.7 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEG07974.1 - 0.039 13.8 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 KEG07974.1 - 0.051 13.3 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KEG07974.1 - 0.081 12.5 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KEG07974.1 - 0.085 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KEG07974.1 - 0.089 13.1 0.1 0.26 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEG07974.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 KEG07974.1 - 0.13 11.7 0.2 0.31 10.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KEG07974.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rer1 PF03248.13 KEG07975.1 - 2e-55 187.1 6.2 2.4e-55 186.9 6.2 1.0 1 0 0 1 1 1 1 Rer1 family TrmO PF01980.16 KEG07976.1 - 8.3e-32 109.9 0.0 1.7e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O PWWP PF00855.17 KEG07976.1 - 6.4e-05 23.3 0.4 0.00022 21.6 0.4 1.9 1 1 0 1 1 1 1 PWWP domain Acetyltransf_3 PF13302.7 KEG07977.1 - 2.2e-19 70.5 0.6 1.8e-10 41.6 0.0 2.4 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEG07977.1 - 1.4e-05 25.3 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEG07977.1 - 2.8e-05 23.8 0.2 0.021 14.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEG07977.1 - 0.00091 19.4 0.0 0.0022 18.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG07977.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein UQ_con PF00179.26 KEG07978.1 - 1.2e-43 148.1 0.0 2.3e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEG07978.1 - 0.0018 18.0 0.7 0.0057 16.3 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic E2 family B UFC1 PF08694.11 KEG07978.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RCR PF12273.8 KEG07978.1 - 0.74 10.5 7.4 1.3 9.7 7.4 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MT PF12777.7 KEG07979.1 - 1.2e-05 24.5 0.5 1.2e-05 24.5 0.5 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Takusan PF04822.13 KEG07979.1 - 0.0027 17.5 5.9 0.0084 16.0 5.9 1.7 1 0 0 1 1 1 1 Takusan WDCP PF15390.6 KEG07979.1 - 2.1 6.6 6.6 0.16 10.4 0.9 1.7 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family SmpA_OmlA PF04355.13 KEG07980.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 SmpA / OmlA family DUF4379 PF14311.6 KEG07981.1 - 1.8e-22 79.4 3.4 7.9e-14 51.8 1.1 2.7 2 0 0 2 2 2 2 Probable Zinc-ribbon domain HypA PF01155.19 KEG07981.1 - 0.024 14.6 0.7 0.62 10.1 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KEG07981.1 - 0.028 14.5 1.0 0.069 13.3 1.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KEG07981.1 - 0.6 10.1 3.3 2 8.4 3.3 1.9 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Rubredoxin_2 PF18073.1 KEG07981.1 - 7.9 6.3 6.9 0.72 9.6 1.0 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Pkinase PF00069.25 KEG07982.1 - 1.6e-61 208.0 0.0 2.4e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG07982.1 - 1.4e-29 103.2 0.0 2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG07982.1 - 6.3e-10 38.8 0.0 9.5e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG07982.1 - 1e-05 24.6 0.1 2.4e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG07982.1 - 0.00031 20.7 6.5 0.0015 18.5 1.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family MMR_HSR1 PF01926.23 KEG07984.1 - 2.9e-15 56.4 0.0 8e-14 51.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG07984.1 - 8.1e-07 28.7 0.0 5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KEG07984.1 - 0.00014 21.2 0.0 0.00041 19.7 0.0 1.8 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KEG07984.1 - 0.00091 19.2 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Hydin_ADK PF17213.3 KEG07984.1 - 0.34 11.2 4.0 4.4 7.5 1.2 2.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 KEG07984.1 - 5 5.8 12.1 1 8.1 8.1 1.9 2 0 0 2 2 2 0 Presenilin Fip1 PF05182.13 KEG07985.1 - 9e-18 63.5 1.2 1.8e-17 62.6 1.2 1.6 1 0 0 1 1 1 1 Fip1 motif zf_CCCH_4 PF18345.1 KEG07985.1 - 0.00013 21.8 2.7 0.00024 21.1 2.7 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KEG07985.1 - 0.00024 20.9 3.0 0.0005 19.9 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG07985.1 - 0.023 15.4 1.6 0.023 15.4 1.6 2.9 2 1 1 3 3 3 0 Torus domain EPL1 PF10513.9 KEG07985.1 - 0.07 13.5 4.5 1.1 9.6 1.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like zf-CCCH_4 PF18044.1 KEG07985.1 - 0.071 12.9 2.5 0.12 12.2 2.5 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger ANAPC_CDC26 PF10471.9 KEG07985.1 - 0.34 11.8 15.2 2.6 8.9 5.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Pex14_N PF04695.13 KEG07985.1 - 0.48 11.1 9.9 4.4 7.9 2.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2-oxoacid_dh PF00198.23 KEG07986.1 - 7e-73 244.9 0.1 1.1e-72 244.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEG07986.1 - 2.4e-17 62.5 0.4 6.2e-17 61.2 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEG07986.1 - 2.3e-12 47.1 0.0 5.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain MRP-L20 PF12824.7 KEG07986.1 - 0.12 12.5 0.3 0.19 11.9 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 RnfC_N PF13375.6 KEG07986.1 - 0.13 12.3 1.0 2.9 7.9 0.3 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Mucin PF01456.17 KEG07987.1 - 0.0029 17.6 5.3 0.0029 17.6 5.3 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein MGTL PF17059.5 KEG07987.1 - 0.16 11.8 3.2 0.36 10.7 3.2 1.6 1 0 0 1 1 1 0 MgtA leader peptide TerB_C PF15615.6 KEG07987.1 - 0.25 11.6 4.2 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 TerB-C domain RXLR PF16810.5 KEG07987.1 - 2.8 8.4 5.3 2.9 8.3 3.7 1.8 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity MOZ_SAS PF01853.18 KEG07989.1 - 1.4e-40 138.8 0.2 2.7e-39 134.7 0.2 2.4 1 1 0 1 1 1 1 MOZ/SAS family HATPase_c PF02518.26 KEG07990.1 - 2.8e-11 43.9 0.0 4.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_gyraseB PF00204.25 KEG07991.1 - 4.5e-07 29.5 0.0 7e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 DNA gyrase B Phos_pyr_kin PF08543.12 KEG07991.1 - 0.096 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DNA_topoisoIV PF00521.20 KEG07992.1 - 2.8e-127 425.2 0.0 4.2e-127 424.6 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KEG07992.1 - 7.6e-42 142.6 1.6 7.6e-42 142.6 1.6 1.8 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM Toprim PF01751.22 KEG07992.1 - 0.085 13.1 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 Toprim domain Pyr_excise PF03013.14 KEG07992.1 - 3.4 7.7 8.1 5.4 7.0 0.0 3.6 4 0 0 4 4 4 0 Pyrimidine dimer DNA glycosylase zf-CCCH PF00642.24 KEG07993.1 - 0.0025 17.7 10.0 0.59 10.1 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG07993.1 - 0.0039 17.2 13.2 0.25 11.4 0.4 3.1 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KEG07993.1 - 0.065 13.1 18.8 0.32 10.9 8.6 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger Torus PF16131.5 KEG07993.1 - 0.18 12.5 7.5 0.54 11.0 2.4 3.1 3 1 1 4 4 4 0 Torus domain zf-CCCH_2 PF14608.6 KEG07993.1 - 1.5 9.4 9.3 15 6.3 0.4 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KEG07994.1 - 0.00062 19.5 1.3 0.00062 19.5 1.3 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KEG07994.1 - 0.0018 18.2 10.2 0.018 14.9 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG07994.1 - 0.24 12.1 2.3 24 5.7 0.1 2.6 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KEG07994.1 - 3.5 8.2 15.1 0.28 11.7 1.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Exo_endo_phos_2 PF14529.6 KEG07997.1 - 5.9e-07 29.4 0.0 7.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase VraX PF17412.2 KEG07997.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function Exo_endo_phos PF03372.23 KEG07997.1 - 0.088 12.3 0.1 0.2 11.2 0.1 1.5 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family DHHC PF01529.20 KEG08001.1 - 2e-18 66.8 1.6 2e-18 66.8 1.6 2.1 1 1 0 2 2 2 1 DHHC palmitoyltransferase 2OG-FeII_Oxy_2 PF13532.6 KEG08002.1 - 5.6e-51 173.5 0.0 8.4e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Coatomer_WDAD PF04053.14 KEG08003.1 - 2e-96 323.8 0.0 2.9e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KEG08003.1 - 1.7e-90 303.7 0.0 2.4e-90 303.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KEG08003.1 - 4e-41 138.2 15.0 5.2e-07 30.3 0.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KEG08003.1 - 0.32 9.6 6.8 8.6 4.9 0.4 4.0 2 2 3 5 5 5 0 Nucleoporin Nup120/160 ESSS PF10183.9 KEG08004.1 - 7e-19 68.0 3.9 8.4e-19 67.7 3.9 1.2 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF883 PF05957.13 KEG08006.1 - 0.49 11.0 6.0 0.17 12.5 1.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3619 PF12279.8 KEG08006.1 - 6.6 7.1 10.2 0.36 11.2 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) SUIM_assoc PF16619.5 KEG08007.1 - 3.6 7.7 9.5 11 6.2 5.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FAD_binding_2 PF00890.24 KEG08008.1 - 8e-81 272.2 1.1 8e-81 272.2 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 KEG08008.1 - 5.3e-20 71.3 0.0 2.1e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_oxidored PF12831.7 KEG08008.1 - 3.2e-12 46.5 0.4 2.1e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KEG08008.1 - 3.3e-09 36.8 7.7 6.6e-08 32.5 6.7 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEG08008.1 - 8e-07 28.6 0.8 3e-06 26.7 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG08008.1 - 4.7e-06 26.7 2.5 1.4e-05 25.2 1.2 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEG08008.1 - 0.00067 18.5 6.9 0.0007 18.4 0.5 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KEG08008.1 - 0.0016 17.6 5.3 0.0017 17.5 0.9 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KEG08008.1 - 0.0093 15.3 1.0 0.019 14.2 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEG08008.1 - 0.076 12.3 1.6 0.18 11.1 1.6 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEG08008.1 - 0.11 11.7 0.1 0.26 10.5 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEG08008.1 - 0.24 10.4 2.0 0.26 10.3 0.6 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KEG08008.1 - 0.3 11.7 2.6 0.77 10.4 0.8 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEG08008.1 - 0.61 9.3 5.3 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Thi4 family NMD3 PF04981.13 KEG08009.1 - 8e-74 248.2 4.6 1.3e-73 247.4 4.6 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KEG08009.1 - 5.8 7.0 11.3 7.8 6.6 4.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon FTR1 PF03239.14 KEG08010.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family DUF3762 PF12591.8 KEG08010.1 - 0.74 10.1 3.1 3.3 8.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3762) RsbU_N PF08673.10 KEG08012.1 - 0.23 11.6 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Phage_holin_5_1 PF06946.11 KEG08018.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 Bromodomain PF00439.25 KEG08020.1 - 0.049 13.7 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Bromodomain MyTH4 PF00784.17 KEG08020.1 - 0.063 13.8 0.2 0.4 11.2 0.2 2.1 2 0 0 2 2 2 0 MyTH4 domain GHMP_kinases_C PF08544.13 KEG08020.1 - 3 8.3 7.0 4.3 7.8 5.6 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal UCR_hinge PF02320.16 KEG08023.1 - 0.0039 17.4 1.7 0.62 10.3 0.1 2.8 2 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF2203 PF09969.9 KEG08023.1 - 0.013 16.3 2.4 0.13 13.0 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 KEG08023.1 - 0.013 15.1 2.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein DNA_repr_REX1B PF14966.6 KEG08023.1 - 0.016 15.8 3.0 0.023 15.4 1.3 2.1 2 0 0 2 2 2 0 DNA repair REX1-B ABA_WDS PF02496.16 KEG08023.1 - 0.077 13.5 7.3 0.19 12.3 0.4 3.0 3 0 0 3 3 3 0 ABA/WDS induced protein DUF1748 PF08520.10 KEG08023.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) SUIM_assoc PF16619.5 KEG08023.1 - 0.14 12.2 5.8 0.43 10.7 5.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Apolipoprotein PF01442.18 KEG08023.1 - 5.6 6.8 10.7 12 5.8 3.9 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain TPR_10 PF13374.6 KEG08024.1 - 0.043 13.7 0.4 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GTP-bdg_M PF16360.5 KEG08024.1 - 0.73 10.5 10.5 5.9 7.6 4.0 2.9 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Phage_Mu_Gam PF07352.12 KEG08024.1 - 1.5 8.7 7.8 2.3 8.1 1.3 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF4337 PF14235.6 KEG08024.1 - 5.8 7.0 8.5 1 9.4 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FH2 PF02181.23 KEG08025.1 - 2.3e-50 171.8 0.0 3.7e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CAMP_factor PF07373.11 KEG08025.1 - 0.076 12.6 1.7 5.7 6.5 0.2 3.1 3 0 0 3 3 3 0 CAMP factor (Cfa) Fez1 PF06818.15 KEG08027.1 - 4e-05 24.1 59.4 0.0037 17.8 1.7 6.2 3 2 3 6 6 6 3 Fez1 ATG16 PF08614.11 KEG08027.1 - 0.0089 16.3 2.6 0.0089 16.3 2.6 7.6 5 2 0 6 6 6 2 Autophagy protein 16 (ATG16) Bcr-Abl_Oligo PF09036.10 KEG08027.1 - 0.014 15.3 0.7 0.014 15.3 0.7 6.2 6 1 1 7 7 7 0 Bcr-Abl oncoprotein oligomerisation domain DivIC PF04977.15 KEG08027.1 - 0.07 12.9 0.3 0.07 12.9 0.3 10.0 8 2 2 11 11 11 0 Septum formation initiator YabA PF06156.13 KEG08027.1 - 0.74 10.5 0.0 0.74 10.5 0.0 7.9 8 1 0 9 9 9 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KEG08027.1 - 0.77 9.8 64.8 0.48 10.5 0.7 8.7 6 2 2 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CEP63 PF17045.5 KEG08027.1 - 1.5 8.6 58.8 0.92 9.4 1.0 6.0 3 2 1 4 4 4 0 Centrosomal protein of 63 kDa FlaC_arch PF05377.11 KEG08027.1 - 2.3 8.7 21.6 70 3.9 0.0 8.5 8 1 1 9 9 9 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KEG08027.1 - 4.9 6.4 70.0 0.25 10.7 6.9 6.0 1 1 5 6 6 6 0 Domain of unknown function (DUF4407) DUF1770 PF08589.10 KEG08028.1 - 0.088 13.8 0.4 0.53 11.3 0.0 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) PH PF00169.29 KEG08028.1 - 0.17 12.4 0.0 0.5 10.9 0.0 1.8 1 0 0 1 1 1 0 PH domain DUF4366 PF14283.6 KEG08028.1 - 0.83 9.7 5.2 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Ribosomal_60s PF00428.19 KEG08028.1 - 1.7 9.3 10.1 3.2 8.4 2.4 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Myc_N PF01056.18 KEG08028.1 - 1.8 8.4 11.0 1.6 8.6 3.4 2.9 3 0 0 3 3 3 0 Myc amino-terminal region TPR_2 PF07719.17 KEG08030.1 - 0.1 12.8 6.5 0.66 10.2 0.8 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG08030.1 - 0.45 11.0 3.2 2.5 8.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG08030.1 - 2.5 9.2 4.2 43 5.3 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG08030.1 - 5.4 7.0 6.2 5.3 7.0 0.9 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TetR_C_7 PF14246.6 KEG08031.1 - 0.12 12.4 6.3 0.18 11.9 0.2 3.3 3 0 0 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain SUIM_assoc PF16619.5 KEG08031.1 - 0.36 10.9 8.6 0.38 10.9 2.2 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG08031.1 - 0.59 9.7 0.0 0.59 9.7 0.0 2.8 2 1 0 2 2 2 0 Spt20 family MMR1 PF08505.10 KEG08032.1 - 0.0047 17.3 23.8 0.04 14.2 13.2 2.2 2 0 0 2 2 2 2 Mitochondrial Myo2 receptor-related protein CCSAP PF15748.5 KEG08032.1 - 0.43 10.7 29.9 1.1 9.4 18.6 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Macoilin PF09726.9 KEG08032.1 - 0.71 8.4 22.1 0.38 9.3 13.0 2.1 2 0 0 2 2 2 0 Macoilin family Plasmodium_Vir PF05795.11 KEG08032.1 - 8.2 5.7 18.4 14 5.0 12.8 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 KEG08032.1 - 8.5 6.4 15.6 6.2 6.8 0.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF5523 PF17661.1 KEG08032.1 - 9.1 5.9 30.5 0.17 11.6 2.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF3017 PF11222.8 KEG08033.1 - 0.037 14.3 3.6 0.052 13.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) RskA PF10099.9 KEG08033.1 - 0.042 14.1 2.7 0.049 13.9 2.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SHS2_Rpb7-N PF03876.17 KEG08034.1 - 1.8e-15 57.1 0.0 3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CRAL_TRIO PF00650.20 KEG08035.1 - 5.6e-29 100.9 0.0 8.7e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEG08035.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UBA_4 PF14555.6 KEG08035.1 - 0.083 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain CRAL_TRIO PF00650.20 KEG08036.1 - 6.1e-34 117.0 0.0 8.9e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KEG08036.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEG08036.1 - 0.0042 17.2 0.0 0.0089 16.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain GIT_CC PF16559.5 KEG08038.1 - 0.0097 15.8 3.0 0.0097 15.8 3.0 1.8 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1465 PF07323.12 KEG08038.1 - 0.014 15.2 2.7 0.11 12.3 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) FapA PF03961.13 KEG08038.1 - 0.02 13.5 2.2 0.027 13.1 2.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CHASE3 PF05227.13 KEG08038.1 - 0.056 13.3 5.8 2.8 7.8 2.0 2.6 1 1 0 2 2 2 0 CHASE3 domain RsbU_N PF08673.10 KEG08038.1 - 0.068 13.3 0.2 0.28 11.3 0.0 2.1 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain Prominin PF05478.11 KEG08038.1 - 0.14 10.1 4.2 0.18 9.7 4.2 1.1 1 0 0 1 1 1 0 Prominin Uso1_p115_C PF04871.13 KEG08038.1 - 0.89 9.9 8.5 0.23 11.8 1.5 2.1 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 KEG08038.1 - 1.5 9.5 7.9 0.8 10.4 4.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF1033 PF06279.11 KEG08038.1 - 2.3 8.4 7.6 13 6.0 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) CLZ PF16526.5 KEG08038.1 - 2.9 8.3 6.5 6.9 7.1 3.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CRISPR_Cas2 PF09827.9 KEG08040.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas2 KptA_kDCL PF18176.1 KEG08041.1 - 9.7e-16 58.1 0.1 3e-15 56.5 0.1 1.8 2 0 0 2 2 2 1 KptA in kinetoplastid DICER domain La_HTH_kDCL PF18177.1 KEG08041.1 - 4e-06 27.0 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 La HTH in kinetoplastid DICER domain Ribonuclease_3 PF00636.26 KEG08041.1 - 0.00042 20.9 0.2 1.6 9.4 0.0 3.4 2 1 1 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KEG08041.1 - 0.022 14.9 0.1 0.5 10.5 0.1 2.5 1 1 0 1 1 1 0 Ribonuclease-III-like Metallophos PF00149.28 KEG08042.1 - 2.6e-33 116.3 0.2 3.7e-33 115.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNA_pol_N PF01194.17 KEG08043.1 - 3.8e-28 97.6 0.8 4.5e-28 97.3 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Yippee-Mis18 PF03226.14 KEG08043.1 - 0.16 12.2 0.8 0.22 11.8 0.8 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ImpA_N PF06812.12 KEG08044.1 - 0.029 14.5 0.6 0.039 14.1 0.6 1.2 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system DUF4483 PF14825.6 KEG08044.1 - 0.055 13.2 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) BT1 PF03092.16 KEG08045.1 - 8.6e-183 608.3 13.2 1.1e-182 608.0 13.2 1.0 1 0 0 1 1 1 1 BT1 family UPF0172 PF03665.13 KEG08046.1 - 6.3e-53 179.7 0.5 7.1e-53 179.5 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.7 KEG08047.1 - 0.00016 22.0 1.4 0.0004 20.7 1.4 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG08047.1 - 0.00019 21.1 0.3 0.00042 20.0 0.3 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KEG08047.1 - 0.035 14.1 1.3 0.67 10.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat zf-rbx1 PF12678.7 KEG08047.1 - 0.14 12.5 0.3 0.31 11.4 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain LRR_1 PF00560.33 KEG08047.1 - 0.38 11.5 2.7 3.4 8.6 2.7 2.7 1 1 0 1 1 1 0 Leucine Rich Repeat WD40 PF00400.32 KEG08049.1 - 2.2e-10 40.9 20.1 0.00099 19.9 0.1 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG08049.1 - 0.0023 18.4 1.2 1.3 9.6 0.1 4.5 5 0 0 5 5 5 1 PQQ-like domain DUF2046 PF09755.9 KEG08049.1 - 0.0081 15.4 0.5 0.014 14.7 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) CortBP2 PF09727.9 KEG08049.1 - 0.022 14.7 1.2 0.045 13.7 1.2 1.4 1 0 0 1 1 1 0 Cortactin-binding protein-2 GAS PF13851.6 KEG08050.1 - 0.0023 17.3 5.9 0.0023 17.3 5.9 3.8 3 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding Sec5 PF15469.6 KEG08050.1 - 0.011 15.5 0.3 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 BRE1 PF08647.11 KEG08050.1 - 0.067 13.3 16.6 0.049 13.7 3.2 3.6 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Ribosomal_L6e PF01159.19 KEG08050.1 - 0.091 13.3 0.5 0.72 10.4 0.7 2.3 2 0 0 2 2 2 0 Ribosomal protein L6e ERAP1_C PF11838.8 KEG08050.1 - 0.55 9.7 8.2 0.45 10.0 0.1 3.3 3 1 1 4 4 4 0 ERAP1-like C-terminal domain DUF629 PF04780.12 KEG08050.1 - 0.65 8.5 6.6 0.17 10.4 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) LCD1 PF09798.9 KEG08050.1 - 0.79 8.2 9.3 0.055 12.0 3.9 1.7 2 0 0 2 2 2 0 DNA damage checkpoint protein IMD PF08397.11 KEG08050.1 - 1.9 7.8 10.2 1.5 8.1 0.2 2.6 2 0 0 2 2 2 0 IRSp53/MIM homology domain Syntaxin-6_N PF09177.11 KEG08050.1 - 2 9.0 15.2 0.55 10.8 1.7 3.7 3 1 0 3 3 3 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 KEG08050.1 - 2.8 8.0 20.8 0.079 13.1 5.5 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 KEG08050.1 - 3.6 8.1 44.8 0.26 11.8 14.4 4.5 2 2 1 4 4 4 0 Apg6 coiled-coil region GIT_CC PF16559.5 KEG08050.1 - 6.7 6.7 7.2 32 4.5 0.3 3.9 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Uteroglobin PF01099.17 KEG08051.1 - 0.017 15.4 1.7 0.079 13.3 1.1 2.5 2 0 0 2 2 2 0 Uteroglobin family MEF2_binding PF09047.10 KEG08051.1 - 0.09 12.6 6.2 0.11 12.3 0.5 2.9 2 0 0 2 2 2 0 MEF2 binding UPF0242 PF06785.11 KEG08051.1 - 0.8 9.8 4.4 0.49 10.5 0.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mucin PF01456.17 KEG08052.1 - 7.5 6.5 25.3 1.9e+03 -1.2 25.3 2.8 1 1 0 1 1 1 0 Mucin-like glycoprotein Mustang PF15682.5 KEG08053.1 - 0.05 13.7 0.0 34 4.6 0.0 3.1 3 0 0 3 3 3 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Heme_oxygenase PF01126.20 KEG08057.1 - 0.065 13.0 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 Heme oxygenase Taxilin PF09728.9 KEG08059.1 - 0.0063 15.7 1.8 0.0063 15.7 1.8 2.0 2 0 0 2 2 2 1 Myosin-like coiled-coil protein eIF_4EBP PF05456.11 KEG08059.1 - 0.015 15.3 0.8 0.033 14.1 0.8 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF5094 PF17015.5 KEG08059.1 - 1.4 9.0 4.0 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) zf-C3HC4 PF00097.25 KEG08061.1 - 1.4e-09 37.6 5.9 1.4e-09 37.6 5.9 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG08061.1 - 7e-09 35.4 5.2 7e-09 35.4 5.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG08061.1 - 1.3e-07 31.5 1.0 1.3e-07 31.5 1.0 3.4 3 2 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEG08061.1 - 2.3e-07 31.0 6.4 2.3e-07 31.0 6.4 2.7 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KEG08061.1 - 1.1e-06 28.5 7.3 1.1e-06 28.5 7.3 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEG08061.1 - 1.1e-06 28.3 7.3 1.1e-06 28.3 7.3 3.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG08061.1 - 3.1e-06 26.9 8.4 0.00012 21.9 4.9 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEG08061.1 - 3e-05 24.1 4.7 3e-05 24.1 4.7 3.5 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 KEG08061.1 - 0.00017 21.8 3.7 0.0034 17.6 0.3 2.6 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-WRNIP1_ubi PF18279.1 KEG08061.1 - 0.00074 20.0 6.3 7.8 7.4 0.3 3.7 3 0 0 3 3 3 2 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-rbx1 PF12678.7 KEG08061.1 - 0.00084 19.6 12.3 0.0063 16.8 7.2 3.2 2 1 1 3 3 3 1 RING-H2 zinc finger domain Zn-C2H2_12 PF18112.1 KEG08061.1 - 0.012 16.0 6.2 5.3 7.6 0.1 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 KEG08061.1 - 0.021 14.8 3.4 0.032 14.3 1.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 KEG08061.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.6 2 1 1 3 3 2 0 TerY-C metal binding domain Zn-ribbon_8 PF09723.10 KEG08061.1 - 0.45 10.7 9.8 12 6.1 1.2 4.3 4 0 0 4 4 4 0 Zinc ribbon domain CitX PF03802.14 KEG08061.1 - 0.73 9.6 5.4 9 6.0 0.7 2.2 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GAGA PF09237.11 KEG08061.1 - 1 9.2 6.5 10 6.0 0.2 3.5 3 0 0 3 3 3 0 GAGA factor Rad50_zn_hook PF04423.14 KEG08061.1 - 1 9.2 6.7 10 6.1 0.2 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif IBR PF01485.21 KEG08061.1 - 1.6 9.0 12.5 4.4 7.6 0.2 3.3 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 KEG08061.1 - 2 8.3 5.1 7.9 6.3 5.1 2.1 1 1 0 1 1 1 0 RING-like zinc finger RecR PF02132.15 KEG08061.1 - 2.9 7.5 9.9 12 5.6 0.2 4.0 4 0 0 4 4 4 0 RecR protein UPF0547 PF10571.9 KEG08061.1 - 5.6 7.1 11.7 65 3.7 0.0 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 FYVE PF01363.21 KEG08061.1 - 5.9 7.1 13.7 39 4.5 10.4 3.2 2 1 0 2 2 2 0 FYVE zinc finger tRNA-synt_1g PF09334.11 KEG08065.1 - 4.9e-97 325.1 0.3 1.9e-96 323.2 0.3 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEG08065.1 - 3.1e-19 68.7 0.6 9.2e-10 37.4 0.5 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KEG08065.1 - 6.5e-08 32.3 0.1 0.0017 17.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MKT1_C PF12246.8 KEG08066.1 - 6e-15 55.2 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KEG08066.1 - 9.6e-11 41.9 0.1 2e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Pex14_N PF04695.13 KEG08067.1 - 0.88 10.2 9.0 1.5 9.5 9.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_N PF01213.19 KEG08067.1 - 0.88 9.0 11.0 1.5 8.3 11.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal APG6_N PF17675.1 KEG08068.1 - 0.0055 17.2 29.9 0.0055 17.2 29.9 6.2 2 1 3 6 6 6 1 Apg6 coiled-coil region Filament PF00038.21 KEG08068.1 - 8.4 5.9 69.7 0.0074 15.9 40.2 3.8 2 1 2 4 4 4 0 Intermediate filament protein DUF3456 PF11938.8 KEG08068.1 - 9.4 6.7 16.6 0.46 11.0 0.1 4.0 2 2 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP DnaJ PF00226.31 KEG08072.1 - 1e-13 51.1 0.1 1.6e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KEG08072.1 - 1.9e-06 27.5 5.8 5.1e-06 26.1 5.8 1.8 1 1 0 1 1 1 1 CSL zinc finger Pep1_7 PF17232.2 KEG08072.1 - 0.09 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Elicitor peptide 1-7 NADH-G_4Fe-4S_3 PF10588.9 KEG08073.1 - 1.6e-15 56.4 0.3 1.6e-15 56.4 0.3 2.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 KEG08073.1 - 7.4e-11 42.0 0.8 1.2e-10 41.3 0.1 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 KEG08073.1 - 2.3e-08 33.9 0.5 6.1e-08 32.5 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KEG08073.1 - 0.12 12.9 7.4 0.082 13.5 2.9 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEG08073.1 - 1.9 8.7 8.4 0.15 12.2 2.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEG08073.1 - 2.2 8.5 7.0 0.24 11.6 1.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain 3HCDH_N PF02737.18 KEG08078.1 - 3.2e-43 147.7 0.0 6.1e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KEG08078.1 - 4.9e-35 121.0 0.5 8.2e-35 120.3 0.5 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEG08078.1 - 8.3e-29 101.1 1.7 4.5e-28 98.7 1.7 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KEG08078.1 - 4.7e-24 84.8 0.0 1.5e-15 57.6 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrkA_N PF02254.18 KEG08078.1 - 0.035 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain YtxH PF12732.7 KEG08079.1 - 6.4 7.4 12.6 0.12 13.0 2.8 2.8 2 2 1 3 3 3 0 YtxH-like protein Pex19 PF04614.12 KEG08079.1 - 7.8 6.2 8.7 18 5.0 8.6 1.7 1 1 0 1 1 1 0 Pex19 protein family MbeB_N PF04837.12 KEG08080.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 MbeB-like, N-term conserved region DNA_pol_phi PF04931.13 KEG08080.1 - 0.055 11.6 0.0 0.055 11.6 0.0 3.7 2 1 1 3 3 3 0 DNA polymerase phi zf-C3HC4 PF00097.25 KEG08081.1 - 0.0018 18.1 12.6 0.0018 18.1 12.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG08081.1 - 0.013 15.3 12.5 0.038 13.8 12.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG08081.1 - 0.019 15.0 8.7 0.058 13.4 8.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KEG08081.1 - 0.021 14.8 14.3 0.021 14.8 14.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KEG08081.1 - 4.2 7.8 19.8 0.34 11.3 13.8 2.4 3 0 0 3 3 3 0 Ring finger domain Meckelin PF09773.9 KEG08082.1 - 1.2e-199 665.4 0.0 1.4e-199 665.2 0.0 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) TPR_16 PF13432.6 KEG08083.1 - 7.5e-07 29.7 0.1 0.11 13.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 KEG08083.1 - 3.3e-05 24.1 1.3 9.4e-05 22.7 0.0 2.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG08083.1 - 6.5e-05 22.7 0.1 1 9.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG08083.1 - 0.0002 21.6 0.5 0.029 14.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG08083.1 - 0.0026 18.2 1.6 0.71 10.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG08083.1 - 0.0049 17.4 0.6 7.8 7.4 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat Thioredoxin PF00085.20 KEG08083.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin TPR_1 PF00515.28 KEG08083.1 - 0.029 14.2 0.1 7.8 6.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HicB_lk_antitox PF15919.5 KEG08083.1 - 0.032 14.3 0.3 0.094 12.8 0.2 1.8 1 1 1 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system GutM PF06923.11 KEG08083.1 - 0.063 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) PEP-utilisers_N PF05524.13 KEG08083.1 - 0.15 12.2 0.7 4.1 7.6 0.8 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DLH PF01738.18 KEG08086.1 - 0.13 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family COMM_domain PF07258.14 KEG08087.1 - 1.8e-07 31.1 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 COMM domain Exo_endo_phos PF03372.23 KEG08089.1 - 2.3e-15 56.7 0.0 5.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KEG08089.1 - 0.039 13.8 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4079 PF13301.6 KEG08090.1 - 0.043 14.0 1.2 1.3 9.2 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF4079) Syndecan PF01034.20 KEG08090.1 - 0.37 10.8 0.0 0.37 10.8 0.0 3.0 3 0 0 3 3 3 0 Syndecan domain Vps52 PF04129.12 KEG08091.1 - 0.0099 14.7 0.1 0.03 13.1 0.0 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family SelB-wing_2 PF09106.11 KEG08095.1 - 0.019 15.2 0.9 2.7 8.2 0.1 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix SMP PF04927.12 KEG08095.1 - 0.11 13.0 4.6 4.9 7.7 0.3 2.3 2 0 0 2 2 2 0 Seed maturation protein Pep_deformylase PF01327.21 KEG08097.1 - 2.1e-17 63.2 0.0 1.1e-16 60.9 0.0 2.0 1 1 0 1 1 1 1 Polypeptide deformylase Retinal PF15449.6 KEG08097.1 - 0.004 15.0 3.1 0.0051 14.7 3.1 1.0 1 0 0 1 1 1 1 Retinal protein DUF4746 PF15928.5 KEG08097.1 - 0.61 9.5 11.9 0.87 9.0 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 KEG08097.1 - 2.1 8.2 10.2 3.4 7.6 10.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pescadillo_N PF06732.11 KEG08098.1 - 4.3e-85 285.6 2.8 1e-84 284.3 2.8 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 KEG08098.1 - 4e-09 36.8 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KEG08098.1 - 0.00013 22.2 0.0 0.00049 20.4 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KEG08098.1 - 0.00035 20.8 0.0 0.00099 19.4 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain LIM_bind PF01803.16 KEG08100.1 - 1.9 8.0 4.2 0.55 9.7 0.6 1.9 2 0 0 2 2 2 0 LIM-domain binding protein OTCace_N PF02729.21 KEG08103.1 - 1.9e-40 138.3 0.1 3.3e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KEG08103.1 - 6e-35 120.6 0.2 1.2e-34 119.6 0.1 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PepSY_TM_like_2 PF16357.5 KEG08103.1 - 0.18 11.8 0.7 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 Putative PepSY_TM-like Pribosyltran PF00156.27 KEG08104.1 - 1.2e-16 60.7 0.8 1.5e-16 60.4 0.8 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEG08104.1 - 8.3e-05 22.1 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KEG08104.1 - 0.00027 20.5 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase DXP_synthase_N PF13292.6 KEG08104.1 - 0.04 13.1 0.1 0.047 12.9 0.1 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase 4PPT_N PF17837.1 KEG08104.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain PDZ_6 PF17820.1 KEG08104.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Proteasome PF00227.26 KEG08106.1 - 1.3e-30 106.3 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1768 PF08719.11 KEG08107.1 - 9.9e-28 97.4 0.0 1.2e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pro_isomerase PF00160.21 KEG08108.1 - 2.5e-53 180.6 3.5 4e-43 147.4 1.6 2.0 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CytochromB561_N PF09786.9 KEG08109.1 - 2.8e-09 36.6 0.0 2.7e-06 26.7 0.0 2.4 1 1 1 2 2 2 2 Cytochrome B561, N terminal SlyX PF04102.12 KEG08111.1 - 3.6e-07 30.7 1.7 0.0011 19.6 0.2 2.1 2 0 0 2 2 2 2 SlyX TSC22 PF01166.18 KEG08111.1 - 0.00067 19.9 0.2 0.17 12.2 0.0 2.2 2 0 0 2 2 2 1 TSC-22/dip/bun family DivIC PF04977.15 KEG08111.1 - 0.0042 16.8 2.7 1.4 8.7 0.6 2.1 2 0 0 2 2 2 2 Septum formation initiator Secretin_N PF03958.17 KEG08111.1 - 0.006 16.9 0.7 0.0084 16.5 0.7 1.3 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain DUF4407 PF14362.6 KEG08111.1 - 0.0085 15.5 4.0 0.015 14.6 4.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 KEG08111.1 - 0.025 14.9 0.6 1.9 8.9 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 KEG08111.1 - 0.027 14.7 1.1 0.22 11.8 1.1 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain FliJ PF02050.16 KEG08111.1 - 0.041 14.1 0.1 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4618 PF15397.6 KEG08111.1 - 0.043 13.2 0.5 0.56 9.6 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF16 PF01519.16 KEG08111.1 - 0.066 13.7 0.4 5.6 7.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spectrin PF00435.21 KEG08111.1 - 0.096 13.2 1.0 1.5 9.3 0.5 2.0 1 1 1 2 2 2 0 Spectrin repeat LPP PF04728.13 KEG08111.1 - 0.098 13.1 0.9 1.8 9.0 0.2 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Cnn_1N PF07989.11 KEG08111.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 KEG08111.1 - 0.14 12.4 0.1 1.5 9.0 0.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1192 PF06698.11 KEG08111.1 - 0.21 11.7 3.3 8.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF5403 PF17395.2 KEG08111.1 - 0.35 11.2 5.2 1.9 8.9 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5403) DUF3138 PF11336.8 KEG08111.1 - 0.46 9.0 6.7 0.48 9.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ROS_MUCR PF05443.11 KEG08111.1 - 0.96 9.5 4.7 1.9 8.6 1.2 2.0 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein Neur_chan_memb PF02932.16 KEG08113.1 - 0.19 11.7 0.1 0.24 11.4 0.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cullin PF00888.22 KEG08115.1 - 8.2e-16 57.7 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEG08115.1 - 9.2e-13 48.0 0.2 2.3e-12 46.7 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_24 PF13412.6 KEG08115.1 - 0.11 12.0 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KEG08115.1 - 0.14 12.1 2.8 3.2 7.7 0.0 3.7 4 0 0 4 4 4 0 MarR family SUIM_assoc PF16619.5 KEG08115.1 - 1.3 9.1 8.1 16 5.7 0.8 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 KEG08117.1 - 5.4e-40 137.4 0.0 2.7e-39 135.2 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08117.1 - 7e-25 87.8 0.0 9.7e-21 74.2 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG08117.1 - 0.00046 19.6 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KEG08117.1 - 0.011 15.4 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KEG08117.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mucin PF01456.17 KEG08117.1 - 0.92 9.5 5.0 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Mucin-like glycoprotein Dynamitin PF04912.14 KEG08118.1 - 0.17 11.2 2.1 6.7 5.9 1.0 2.2 1 1 0 2 2 2 0 Dynamitin Glyco_transf_15 PF01793.16 KEG08119.1 - 1.7e-36 126.2 0.0 2.1e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 KEG08120.1 - 4.9e-09 35.9 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Evr1_Alr PF04777.13 KEG08121.1 - 8.4e-20 71.1 0.7 1.8e-19 70.0 0.7 1.6 1 0 0 1 1 1 1 Erv1 / Alr family ThiF PF00899.21 KEG08122.1 - 7.7e-51 172.8 0.0 1.1e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 KEG08122.1 - 0.00054 20.5 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 PglD N-terminal domain ApbA PF02558.16 KEG08122.1 - 0.002 17.8 0.5 0.0055 16.4 0.0 2.1 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KEG08122.1 - 0.0024 17.3 0.1 0.0053 16.1 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEG08122.1 - 0.0047 17.2 0.4 0.029 14.6 0.0 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KEG08122.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KEG08122.1 - 0.013 15.4 0.3 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SUIM_assoc PF16619.5 KEG08122.1 - 0.023 14.7 1.1 0.039 14.0 1.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Shikimate_DH PF01488.20 KEG08122.1 - 0.05 13.7 1.4 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KEG08122.1 - 0.077 13.3 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 KEG08122.1 - 0.085 13.3 0.1 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding LPP20 PF02169.16 KEG08122.1 - 2.3 8.7 7.2 4.5 7.7 2.8 2.8 3 0 0 3 3 3 0 LPP20 lipoprotein Rad9 PF04139.13 KEG08123.1 - 1.3e-08 34.6 0.0 3.1e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Rad9 Fer4_17 PF13534.6 KEG08124.1 - 0.00047 20.6 0.2 0.0011 19.5 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEG08124.1 - 0.00093 19.6 0.5 0.0022 18.4 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEG08124.1 - 0.0015 18.6 0.2 0.0041 17.2 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEG08124.1 - 0.0066 16.6 0.2 0.021 15.0 0.2 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEG08124.1 - 0.074 13.6 1.2 0.074 13.6 1.2 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L6e PF01159.19 KEG08125.1 - 9e-29 100.2 2.3 1e-28 100.1 0.1 2.1 2 1 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.29 KEG08125.1 - 0.0053 16.7 0.0 0.053 13.5 0.0 2.6 3 0 0 3 3 3 1 KOW motif ParE-like_toxin PF15781.5 KEG08125.1 - 1.5 8.8 3.9 0.57 10.2 0.1 2.2 2 1 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system OAD_gamma PF04277.13 KEG08125.1 - 9.8 6.8 9.9 2.6 8.7 4.9 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CENP-X PF09415.10 KEG08127.1 - 5.5 7.4 7.6 1.1 9.7 0.2 3.2 3 0 0 3 3 3 0 CENP-S associating Centromere protein X DUF4471 PF14740.6 KEG08128.1 - 1.3e-68 231.5 0.1 2.1e-68 230.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 KEG08128.1 - 7e-14 51.8 0.0 2.7e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) Metallophos PF00149.28 KEG08130.1 - 0.016 15.7 0.1 0.12 12.9 0.1 2.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF4131 PF13567.6 KEG08130.1 - 0.95 9.1 8.7 0.85 9.2 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HCR PF07111.12 KEG08131.1 - 0.25 9.4 7.3 2.1 6.3 1.6 2.2 1 1 1 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) DUF3060 PF11259.8 KEG08131.1 - 0.25 11.0 5.2 4.4 7.1 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3060) DUF4523 PF15023.6 KEG08131.1 - 0.31 10.8 2.3 20 5.0 2.3 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) EpCAM_N PF18635.1 KEG08131.1 - 2.7 8.2 16.5 1.5e+02 2.7 0.2 6.7 1 1 7 8 8 8 0 Epithelial cell adhesion molecule N-terminal domain Rad1 PF02144.16 KEG08132.1 - 7.6e-07 28.5 0.0 7.2e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 TPR_2 PF07719.17 KEG08138.1 - 6.7e-07 28.9 36.4 0.06 13.5 0.5 8.9 10 0 0 10 10 9 4 Tetratricopeptide repeat PspA_IM30 PF04012.12 KEG08138.1 - 0.0024 17.5 8.5 0.0024 17.5 8.5 2.4 2 0 0 2 2 2 1 PspA/IM30 family TPR_1 PF00515.28 KEG08138.1 - 0.0028 17.4 19.3 0.26 11.2 0.8 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG08138.1 - 0.0048 17.0 13.8 0.064 13.5 0.2 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat MbeB_N PF04837.12 KEG08138.1 - 0.006 16.9 0.3 0.027 14.7 0.0 2.3 2 0 0 2 2 1 1 MbeB-like, N-term conserved region TPR_9 PF13371.6 KEG08138.1 - 0.018 15.2 18.7 0.25 11.5 0.2 5.4 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 KEG08138.1 - 0.072 12.8 5.5 6.2 6.5 0.1 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) IFT20 PF14931.6 KEG08138.1 - 0.077 13.2 1.7 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Zwint PF15556.6 KEG08138.1 - 0.17 11.3 8.2 0.016 14.7 2.5 2.0 2 0 0 2 2 2 0 ZW10 interactor Ntox28 PF15605.6 KEG08138.1 - 0.29 11.4 2.0 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Bacterial toxin 28 Sel1 PF08238.12 KEG08138.1 - 0.79 10.5 5.9 14 6.5 0.4 4.1 3 0 0 3 3 3 0 Sel1 repeat RskA PF10099.9 KEG08138.1 - 0.84 9.9 8.0 0.13 12.5 2.7 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TPR_12 PF13424.6 KEG08138.1 - 2 8.7 45.5 0.42 10.9 1.3 7.8 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG08138.1 - 4.2 7.6 0.0 4.2 7.6 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat mono-CXXC PF15626.6 KEG08139.1 - 0.0074 16.6 0.9 0.038 14.3 0.9 2.3 1 0 0 1 1 1 1 single CXXC unit TMEM164 PF14808.6 KEG08139.1 - 0.21 10.9 0.2 0.38 10.1 0.2 1.3 1 0 0 1 1 1 0 TMEM164 family MAT1 PF06391.13 KEG08139.1 - 0.24 11.2 2.2 1.9 8.3 0.1 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Foamy_virus_ENV PF03408.14 KEG08140.1 - 0.035 12.0 4.3 0.042 11.7 4.3 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Shisa PF13908.6 KEG08140.1 - 0.065 13.5 3.8 0.076 13.2 3.8 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Vps54_N PF10475.9 KEG08142.1 - 2.8e-18 66.2 6.5 2.8e-18 66.2 6.5 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KEG08142.1 - 5.7e-08 32.8 0.6 2.6e-07 30.7 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) RE_Alw26IDE PF09665.10 KEG08142.1 - 0.0064 15.7 0.1 0.018 14.3 0.0 1.6 1 1 0 1 1 1 1 Type II restriction endonuclease (RE_Alw26IDE) Glyco_transf_8 PF01501.20 KEG08145.1 - 0.021 14.4 0.3 1.1 8.7 0.1 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 8 FtsX PF02687.21 KEG08147.1 - 4.3e-15 56.0 22.3 3.1e-11 43.6 6.1 5.8 5 1 0 5 5 5 2 FtsX-like permease family Phage_holin_3_3 PF16083.5 KEG08147.1 - 6.4 7.0 18.5 1.1 9.4 0.7 4.6 3 1 1 4 4 4 0 LydA holin phage, holin superfamily III HCV_NS5a_1a PF08300.13 KEG08149.1 - 0.046 13.8 0.6 8.8 6.5 0.0 2.6 1 1 1 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain LRR_4 PF12799.7 KEG08151.1 - 1.7e-33 114.1 28.1 0.0042 17.5 0.2 18.9 7 7 18 26 26 26 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG08151.1 - 8.4e-13 47.9 30.0 0.026 14.3 1.3 13.0 11 3 3 15 15 15 5 Leucine rich repeat LRR_6 PF13516.6 KEG08151.1 - 1.2e-09 37.4 52.0 0.067 13.3 0.1 20.1 25 1 1 26 26 26 3 Leucine Rich repeat LRR_5 PF13306.6 KEG08151.1 - 0.021 14.8 0.1 8.6 6.3 0.1 4.8 5 1 0 5 5 5 0 BspA type Leucine rich repeat region (6 copies) COX5A PF02284.16 KEG08151.1 - 0.034 14.2 0.3 0.44 10.6 0.0 3.0 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va BESS PF02944.20 KEG08151.1 - 0.037 13.9 3.1 0.85 9.5 0.1 3.0 2 0 0 2 2 2 0 BESS motif NP1-WLL PF11733.8 KEG08151.1 - 0.045 13.5 0.0 67 3.1 0.0 4.1 5 0 0 5 5 5 0 Non-capsid protein NP1 DUF705 PF05152.12 KEG08151.1 - 0.13 11.7 0.1 22 4.4 0.0 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF705) LRR_1 PF00560.33 KEG08151.1 - 0.88 10.4 27.6 77 4.5 0.7 14.0 18 1 0 18 18 18 0 Leucine Rich Repeat Porin_3 PF01459.22 KEG08152.1 - 0.053 13.0 0.2 0.072 12.5 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic porin WD40 PF00400.32 KEG08153.1 - 5.3e-08 33.4 7.3 0.0012 19.6 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 KEG08153.1 - 5.5e-07 29.5 0.3 4.9e-05 23.1 0.0 2.8 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 KEG08153.1 - 9e-06 25.9 0.7 0.15 12.4 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FHIPEP PF00771.20 KEG08153.1 - 0.013 14.0 2.9 0.022 13.2 2.9 1.3 1 0 0 1 1 1 0 FHIPEP family TPR_2 PF07719.17 KEG08153.1 - 0.03 14.4 0.1 0.36 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CPSF100_C PF13299.6 KEG08153.1 - 1.6 8.9 6.5 3.5 7.8 6.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Rxt3 PF08642.10 KEG08153.1 - 1.8 9.4 3.5 4.3 8.1 3.5 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PAT1 PF09770.9 KEG08153.1 - 3.9 5.6 35.2 6.4 4.9 35.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 KEG08153.1 - 4.6 6.2 5.7 8 5.4 5.7 1.3 1 0 0 1 1 1 0 CLN3 protein VIT1 PF01988.19 KEG08153.1 - 7.1 6.4 8.0 11 5.8 5.5 2.4 3 0 0 3 3 3 0 VIT family MORN PF02493.20 KEG08154.1 - 2.3e-21 74.4 23.3 1.5e-05 24.6 0.3 6.9 6 0 0 6 6 6 6 MORN repeat DUF3048_C PF17479.2 KEG08154.1 - 0.016 15.5 0.4 8.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain DEAD PF00270.29 KEG08155.1 - 1.7e-39 135.4 0.0 3.3e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG08155.1 - 3.8e-23 82.0 0.0 1.1e-22 80.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEG08155.1 - 0.00072 19.9 0.1 0.014 15.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain ResIII PF04851.15 KEG08155.1 - 0.0011 19.0 0.0 0.0055 16.7 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KEG08155.1 - 0.0031 16.9 0.0 0.027 13.8 0.0 2.3 2 0 0 2 2 2 1 SecA DEAD-like domain Cwf_Cwc_15 PF04889.12 KEG08155.1 - 3.7 7.2 14.5 2 8.1 2.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Adaptin_N PF01602.20 KEG08156.1 - 3.8e-83 279.8 0.3 2.7e-75 253.9 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KEG08156.1 - 1.7e-09 37.9 0.1 5.7e-06 26.5 0.0 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEG08156.1 - 0.00046 20.2 4.1 3.7 8.1 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KEG08156.1 - 0.0025 18.3 0.9 6.6 7.3 0.0 4.5 4 0 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KEG08156.1 - 0.057 14.0 0.1 1.7 9.3 0.0 3.0 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region TFIIA PF03153.13 KEG08157.1 - 0.0017 18.5 0.8 0.0017 18.4 0.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 KEG08157.1 - 0.11 11.6 1.1 0.15 11.1 1.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein KCNQ2_u3 PF16642.5 KEG08157.1 - 0.15 13.1 11.9 0.061 14.3 7.0 2.2 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Spt20 PF12090.8 KEG08157.1 - 0.41 10.2 10.1 0.55 9.8 10.1 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KEG08157.1 - 0.57 10.3 13.0 0.056 13.5 7.9 2.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4106 PF13388.6 KEG08157.1 - 1.2 8.3 6.6 1.6 7.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) LSM PF01423.22 KEG08159.1 - 1.2e-09 37.7 0.0 2.5e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.25 KEG08160.1 - 2.4e-73 246.8 0.0 2.7e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08160.1 - 1e-31 110.2 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEG08160.1 - 0.00031 19.8 0.0 0.0028 16.6 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG08160.1 - 0.0015 18.5 0.1 0.11 12.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KEG08160.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KEG08160.1 - 0.11 11.9 0.1 0.25 10.7 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Motile_Sperm PF00635.26 KEG08161.1 - 0.0057 16.5 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Coiled-coil_56 PF09813.9 KEG08162.1 - 0.15 12.2 0.6 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 zf-CCHC_3 PF13917.6 KEG08163.1 - 2.3e-06 27.4 12.7 0.0076 16.2 0.0 3.6 3 0 0 3 3 3 2 Zinc knuckle OTT_1508_deam PF14441.6 KEG08163.1 - 0.066 13.2 1.4 2.3 8.3 0.3 2.6 2 0 0 2 2 2 0 OTT_1508-like deaminase zinc-ribbons_6 PF07191.12 KEG08163.1 - 2.6 8.1 14.8 5.3 7.1 2.8 3.4 3 0 0 3 3 3 0 zinc-ribbons Spt20 PF12090.8 KEG08163.1 - 3.8 7.1 11.4 7.1 6.2 11.4 1.4 1 0 0 1 1 1 0 Spt20 family DAD PF02109.16 KEG08165.1 - 0.032 14.5 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 DAD family Sigma_reg_N PF13800.6 KEG08165.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TPR_1 PF00515.28 KEG08168.1 - 8.2e-90 291.3 31.6 2.7e-08 33.3 0.0 14.1 14 1 0 14 14 14 13 Tetratricopeptide repeat TPR_2 PF07719.17 KEG08168.1 - 5.5e-80 257.2 27.0 2e-07 30.6 0.0 14.0 14 0 0 14 14 14 13 Tetratricopeptide repeat TPR_11 PF13414.6 KEG08168.1 - 1.9e-65 216.3 29.2 4e-07 29.6 0.1 12.9 5 2 7 12 12 12 10 TPR repeat TPR_17 PF13431.6 KEG08168.1 - 3.7e-55 180.4 21.0 3.6e-05 23.8 0.0 13.6 14 1 0 14 14 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 KEG08168.1 - 6e-50 163.3 19.1 2.5e-05 24.1 0.0 13.7 14 0 0 14 14 13 9 Tetratricopeptide repeat TPR_9 PF13371.6 KEG08168.1 - 5.7e-40 135.3 26.7 9e-05 22.5 0.0 11.9 4 4 7 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.6 KEG08168.1 - 4.7e-38 129.6 25.6 3.7e-07 30.7 0.0 9.7 6 3 1 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEG08168.1 - 9.5e-36 121.9 38.4 5.1e-08 33.1 2.2 10.9 5 3 7 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.6 KEG08168.1 - 6.3e-22 75.9 26.8 0.021 14.8 0.1 13.0 11 2 2 13 13 13 5 Tetratricopeptide repeat TPR_14 PF13428.6 KEG08168.1 - 7.3e-21 73.1 20.6 0.082 13.8 0.1 11.4 7 4 5 12 12 12 5 Tetratricopeptide repeat TPR_6 PF13174.6 KEG08168.1 - 2.6e-20 71.7 15.7 0.46 11.2 0.0 12.7 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEG08168.1 - 2.4e-18 66.4 25.3 0.0063 17.0 1.1 9.7 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 KEG08168.1 - 4.8e-14 51.7 30.8 0.037 13.9 0.1 11.3 11 0 0 11 11 11 5 Tetratricopeptide repeat SHNi-TPR PF10516.9 KEG08168.1 - 1.3e-13 50.2 13.4 0.35 10.4 0.0 10.9 11 0 0 11 11 10 3 SHNi-TPR NARP1 PF12569.8 KEG08168.1 - 7.7e-10 38.3 11.9 0.0067 15.4 0.1 5.9 4 1 3 7 7 7 3 NMDA receptor-regulated protein 1 BTAD PF03704.17 KEG08168.1 - 2.7e-09 37.6 18.5 0.059 13.8 0.2 7.1 3 1 5 8 8 8 2 Bacterial transcriptional activator domain TPR_15 PF13429.6 KEG08168.1 - 1.4e-07 31.0 6.9 0.003 16.8 0.1 6.6 3 2 3 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 KEG08168.1 - 1.2e-05 25.4 6.3 4.1 7.5 0.0 7.5 3 3 5 8 8 8 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 KEG08168.1 - 1.4e-05 25.0 2.3 1.6 8.9 0.0 7.0 5 3 2 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KEG08168.1 - 0.0004 20.6 21.9 0.46 10.7 1.5 7.4 4 2 3 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC5 PF12862.7 KEG08168.1 - 0.0011 19.0 1.3 7.6 6.7 0.0 5.1 5 2 0 5 5 5 0 Anaphase-promoting complex subunit 5 TOM20_plant PF06552.12 KEG08168.1 - 0.0013 18.5 1.2 0.96 9.2 0.1 4.0 3 1 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 FAT PF02259.23 KEG08168.1 - 0.0018 17.6 1.2 1.2 8.2 0.1 3.3 1 1 2 3 3 3 2 FAT domain TPR_4 PF07721.14 KEG08168.1 - 0.049 14.3 9.5 1.5e+02 3.4 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEG08168.1 - 0.074 13.4 14.3 0.2 12.0 0.1 6.1 6 2 1 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 KEG08168.1 - 0.23 11.5 30.0 13 5.9 0.2 9.7 11 0 0 11 11 11 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 KEG08168.1 - 0.97 9.1 12.3 1.7 8.3 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat-like domain HTH_Bact PF18768.1 KEG08168.1 - 1.1 8.9 5.0 88 2.8 0.0 5.7 7 1 0 7 7 6 0 Helix-turn-helix bacterial domain TPR_5 PF12688.7 KEG08168.1 - 1.5 9.1 16.6 14 6.0 0.5 5.7 8 1 0 8 8 5 0 Tetratrico peptide repeat TPR_3 PF07720.12 KEG08168.1 - 5.7 7.0 14.9 11 6.1 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat LSM PF01423.22 KEG08169.1 - 8.3e-11 41.4 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEG08169.1 - 0.0045 17.1 0.0 0.011 15.9 0.0 1.6 1 1 1 2 2 2 1 Ataxin 2 SM domain KH_8 PF17903.1 KEG08170.1 - 2.4e-25 88.4 0.2 6e-25 87.1 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KEG08170.1 - 0.14 12.0 0.2 0.4 10.6 0.2 1.9 2 0 0 2 2 2 0 KH domain Alpha_adaptinC2 PF02883.20 KEG08171.1 - 0.0034 17.7 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 Adaptin C-terminal domain COE1_DBD PF16422.5 KEG08172.1 - 0.0068 15.9 0.1 0.0099 15.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain Sds3 PF08598.11 KEG08172.1 - 0.2 11.6 1.0 0.31 11.0 1.0 1.2 1 0 0 1 1 1 0 Sds3-like DUF2150 PF09920.9 KEG08172.1 - 0.22 11.5 0.4 0.74 9.8 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Sugarporin_N PF11471.8 KEG08173.1 - 0.15 12.1 4.0 0.35 10.9 4.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Otopetrin PF03189.13 KEG08174.1 - 0.0096 14.8 0.5 0.015 14.1 0.5 1.3 1 0 0 1 1 1 1 Otopetrin Med15 PF09606.10 KEG08174.1 - 0.11 11.2 29.6 0.19 10.4 29.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 KEG08174.1 - 0.26 9.5 30.6 0.46 8.7 30.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 JIP_LZII PF16471.5 KEG08174.1 - 0.47 10.7 4.6 1.4 9.1 0.5 2.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Zip PF02535.22 KEG08174.1 - 2.4 7.3 17.9 6.2 5.9 17.9 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter Spem1 PF15670.5 KEG08174.1 - 4.4 6.8 16.9 9.1 5.8 16.9 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 VIR_N PF15912.5 KEG08174.1 - 4.7 6.7 17.0 0.39 10.3 11.9 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal DUF2870 PF11069.8 KEG08175.1 - 1.6e-22 79.7 0.0 3.8e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DFRP_C PF16543.5 KEG08175.1 - 0.56 10.7 3.8 0.77 10.3 0.1 2.8 2 1 1 3 3 3 0 DRG Family Regulatory Proteins, Tma46 SMAP PF15477.6 KEG08176.1 - 8.8e-09 36.2 0.6 8.8e-09 36.2 0.6 1.8 2 0 0 2 2 2 1 Small acidic protein family Serglycin PF04360.12 KEG08178.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Serglycin zf-RING_UBOX PF13445.6 KEG08180.1 - 7.6e-07 29.1 0.9 7.6e-07 29.1 0.9 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEG08180.1 - 2.6e-06 27.2 1.6 2.6e-06 27.2 1.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) EF-hand_6 PF13405.6 KEG08180.1 - 5.3e-06 25.9 0.2 0.002 17.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KEG08180.1 - 5.7e-06 26.7 0.3 0.025 15.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair zf-C3HC4 PF00097.25 KEG08180.1 - 6.4e-06 25.9 3.0 6.4e-06 25.9 3.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.32 KEG08180.1 - 2.7e-05 23.4 0.1 0.022 14.3 0.0 2.6 2 0 0 2 2 2 2 EF hand zf-C3HC4_4 PF15227.6 KEG08180.1 - 0.00018 21.6 2.7 0.00018 21.6 2.7 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KEG08180.1 - 0.00023 21.0 0.6 0.00079 19.3 0.6 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KEG08180.1 - 0.0003 20.7 4.7 0.0003 20.7 4.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEG08180.1 - 0.00054 19.8 0.9 0.00054 19.8 0.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG08180.1 - 0.0019 18.1 2.4 0.0019 18.1 2.4 3.2 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEG08180.1 - 0.0068 16.7 7.9 0.0068 16.7 7.9 3.3 2 1 1 3 3 2 1 Ring finger domain EF-hand_11 PF08976.11 KEG08180.1 - 0.0089 16.9 0.0 1 10.3 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KEG08180.1 - 0.023 14.5 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Ank_2 PF12796.7 KEG08183.1 - 3.2e-17 62.9 0.7 5.9e-07 30.0 0.1 4.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG08183.1 - 6.3e-16 58.5 1.5 2.4e-06 28.0 0.1 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEG08183.1 - 2.2e-15 56.5 5.9 4.1e-08 33.3 0.7 4.9 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KEG08183.1 - 7.7e-15 54.6 8.5 0.00035 20.9 0.1 7.0 7 1 0 7 7 7 3 Ankyrin repeat DHHC PF01529.20 KEG08183.1 - 1.1e-14 54.7 0.1 1.1e-14 54.7 0.1 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.6 KEG08183.1 - 4.1e-13 48.2 11.1 0.011 16.2 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Adeno_E4_34 PF04528.13 KEG08183.1 - 1.2 8.9 4.9 7.1 6.5 3.1 2.4 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region STN1_2 PF09170.10 KEG08185.1 - 0.49 10.6 3.7 1.1 9.5 3.7 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF641 PF04859.12 KEG08185.1 - 4.5 7.6 13.3 0.55 10.6 7.0 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 KEG08185.1 - 5.6 6.8 14.0 0.85 9.4 3.3 2.9 1 1 0 2 2 2 0 Septum formation initiator SAT PF16073.5 KEG08186.1 - 0.035 13.8 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis PP2C PF00481.21 KEG08188.1 - 4.1e-53 180.7 0.0 4.9e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KEG08188.1 - 9e-05 22.2 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEG08188.1 - 0.0045 16.9 0.1 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Sec7 PF01369.20 KEG08189.1 - 2.9e-45 154.2 1.1 1.5e-44 151.9 0.2 2.2 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 KEG08189.1 - 1e-20 74.2 6.5 2e-20 73.3 1.0 3.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KEG08189.1 - 1e-17 63.7 0.2 3.7e-17 61.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) NIF PF03031.18 KEG08194.1 - 8.4e-31 106.8 0.0 2.9e-30 105.1 0.0 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase CBM_1 PF00734.18 KEG08194.1 - 1.4 8.9 4.2 0.87 9.6 0.9 2.4 2 0 0 2 2 2 0 Fungal cellulose binding domain Mito_carr PF00153.27 KEG08195.1 - 7.2e-40 134.8 3.6 1.2e-13 50.8 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEG08195.1 - 0.00024 20.3 0.7 0.42 9.7 0.1 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Alanine_zipper PF11839.8 KEG08196.1 - 0.00044 20.6 9.4 0.0079 16.5 0.1 2.2 2 0 0 2 2 2 2 Alanine-zipper, major outer membrane lipoprotein GARP PF16731.5 KEG08196.1 - 0.00053 19.7 11.1 0.00061 19.5 11.1 1.1 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma ISG65-75 PF11727.8 KEG08196.1 - 0.11 11.8 7.7 0.12 11.6 7.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Mucin PF01456.17 KEG08197.1 - 0.012 15.5 1.3 0.016 15.2 1.3 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein FAM24 PF15193.6 KEG08197.1 - 0.24 12.2 2.1 0.52 11.1 2.1 1.5 1 0 0 1 1 1 0 FAM24 family Mucin PF01456.17 KEG08198.1 - 0.092 12.7 25.9 0.1 12.6 7.0 2.9 3 1 0 3 3 3 0 Mucin-like glycoprotein DUF3865 PF12981.7 KEG08198.1 - 0.11 12.3 0.4 7.9 6.3 0.1 2.5 1 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) Rx_N PF18052.1 KEG08199.1 - 0.015 15.5 2.6 0.015 15.5 2.6 3.3 3 0 0 3 3 3 0 Rx N-terminal domain Salt_tol_Pase PF09506.10 KEG08199.1 - 0.22 10.2 2.2 0.35 9.6 2.2 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) UvrD_C PF13361.6 KEG08200.1 - 0.57 9.5 4.2 0.15 11.4 0.4 1.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Acetyltransf_1 PF00583.25 KEG08204.1 - 2.1e-11 44.1 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEG08204.1 - 1.1e-07 32.1 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG08204.1 - 4.2e-05 23.4 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KEG08204.1 - 9.1e-05 22.4 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEG08204.1 - 0.0048 16.6 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hormone_2 PF00123.20 KEG08205.1 - 0.2 11.6 0.4 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Peptide hormone Baculo_PEP_C PF04513.12 KEG08205.1 - 0.38 10.8 3.0 4.3 7.4 0.1 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_S19 PF00203.21 KEG08206.1 - 1e-31 108.6 0.4 1.5e-31 108.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 KEG08206.1 - 0.019 14.8 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF1663 PF07909.11 KEG08207.1 - 1.5e-45 155.9 22.4 3.2e-43 148.2 3.0 2.5 2 1 1 3 3 3 3 Protein of unknown function (DUF1663) SKA1 PF07160.12 KEG08208.1 - 0.05 13.4 0.8 0.085 12.7 0.8 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0524 PF15823.5 KEG08208.1 - 0.063 12.7 0.8 5.4 6.3 0.0 2.1 2 0 0 2 2 2 0 UPF0524 of C3orf70 H_PPase PF03030.16 KEG08209.1 - 6.3e-239 795.0 30.8 6.3e-239 795.0 30.8 1.7 1 1 1 2 2 2 1 Inorganic H+ pyrophosphatase SUIM_assoc PF16619.5 KEG08212.1 - 0.28 11.3 4.1 0.91 9.6 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Senescence_reg PF04520.13 KEG08212.1 - 4.5 8.1 8.0 25 5.7 0.0 3.0 3 0 0 3 3 3 0 Senescence regulator CorA PF01544.18 KEG08216.1 - 1.3e-13 50.9 0.0 9.2e-13 48.1 0.0 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.18 KEG08217.1 - 7.5e-17 61.6 0.0 4.8e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein BOF PF04076.13 KEG08217.1 - 0.15 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein CorA PF01544.18 KEG08218.1 - 3.5e-09 36.4 0.1 4.8e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.29 KEG08219.1 - 1.3e-36 125.9 0.0 2.3e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG08219.1 - 1.3e-07 31.3 0.1 3.2e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEG08219.1 - 6.7e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEG08219.1 - 0.0008 19.4 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG08219.1 - 0.00096 19.6 0.1 0.0037 17.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KEG08219.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KEG08219.1 - 0.021 15.1 0.0 0.13 12.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KEG08219.1 - 0.045 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps4_C PF09336.10 KEG08219.1 - 0.058 13.4 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KEG08219.1 - 0.091 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEG08219.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PQ-loop PF04193.14 KEG08221.1 - 5.8e-24 83.6 1.2 3.1e-17 62.1 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KEG08221.1 - 0.011 16.5 4.8 0.036 14.9 4.8 1.9 1 1 0 1 1 1 0 ER lumen protein retaining receptor MDMPI_N PF11716.8 KEG08221.1 - 0.069 13.8 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Pkinase PF00069.25 KEG08223.1 - 3.7e-23 82.2 0.1 1.1e-13 51.2 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08223.1 - 1.9e-18 66.7 0.9 5.1e-10 39.1 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KEG08223.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 KEG08228.1 - 9.7e-24 83.1 0.3 1.1e-12 47.7 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein NYD-SP28_assoc PF14775.6 KEG08230.1 - 5.1e-23 80.9 0.7 5.1e-23 80.9 0.7 4.6 5 0 0 5 5 5 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 KEG08230.1 - 6.4e-18 64.7 11.3 6.4e-18 64.7 11.3 6.3 4 2 2 7 7 7 1 Sperm tail DUF1882 PF08966.11 KEG08230.1 - 0.032 14.5 0.2 0.091 13.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) DivIC PF04977.15 KEG08230.1 - 0.077 12.8 0.3 0.077 12.8 0.3 7.3 7 1 1 8 8 8 0 Septum formation initiator PikAIV_N PF18605.1 KEG08230.1 - 0.077 12.6 10.9 1.5 8.4 0.4 4.1 2 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF5344 PF17279.2 KEG08230.1 - 5.6 7.6 13.0 3.9 8.1 0.5 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5344) FliD_C PF07195.12 KEG08230.1 - 6.5 6.1 24.1 2.2 7.6 10.0 3.8 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF1759 PF03564.15 KEG08230.1 - 7.2 6.5 12.7 1.5 8.7 1.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) SRI PF08236.11 KEG08232.1 - 0.00021 21.4 0.1 0.00046 20.3 0.1 1.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWPM-19 PF05512.11 KEG08232.1 - 0.092 12.9 2.3 0.11 12.7 2.4 1.4 1 1 0 1 1 1 0 AWPM-19-like family MCCD1 PF15707.5 KEG08232.1 - 0.29 11.6 5.5 0.44 11.0 5.2 1.5 1 1 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 SpoU_methylase PF00588.19 KEG08234.1 - 1e-10 41.9 0.1 1.9e-08 34.6 0.0 2.4 2 1 0 2 2 2 2 SpoU rRNA Methylase family SUIM_assoc PF16619.5 KEG08234.1 - 0.17 11.9 7.4 1.8 8.7 2.0 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 IHABP4_N PF16174.5 KEG08234.1 - 0.26 11.9 5.2 1.4 9.5 1.6 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Androgen_recep PF02166.16 KEG08234.1 - 4.5 6.0 10.6 6.7 5.4 9.7 1.5 1 1 0 1 1 1 0 Androgen receptor Cnd2 PF05786.14 KEG08238.1 - 2.4e-13 49.7 0.0 2.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Rrn6 PF10214.9 KEG08238.1 - 0.094 11.2 0.8 0.099 11.1 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA PF00004.29 KEG08239.1 - 1.9e-40 138.4 0.0 3.5e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG08239.1 - 1.4e-09 37.6 0.3 5e-09 35.8 0.1 2.1 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 KEG08239.1 - 3.4e-07 30.2 0.3 8e-07 29.0 0.3 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KEG08239.1 - 5.8e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEG08239.1 - 2.6e-05 24.7 0.0 0.00019 21.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEG08239.1 - 8.5e-05 22.6 0.1 0.00091 19.2 0.0 2.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG08239.1 - 0.00016 22.0 0.3 0.0058 16.9 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KEG08239.1 - 0.0015 18.3 0.0 0.0041 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 KEG08239.1 - 0.0024 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEG08239.1 - 0.0028 17.1 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KEG08239.1 - 0.0029 18.1 0.3 0.007 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KEG08239.1 - 0.0089 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KEG08239.1 - 0.0094 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KEG08239.1 - 0.013 15.1 0.3 0.063 12.8 0.1 2.3 2 1 1 3 3 2 0 AAA domain ATPase PF06745.13 KEG08239.1 - 0.013 14.8 0.0 1.3 8.3 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 KEG08239.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KEG08239.1 - 0.016 15.4 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KEG08239.1 - 0.019 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEG08239.1 - 0.023 14.6 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_2 PF07724.14 KEG08239.1 - 0.036 14.2 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KEG08239.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KEG08239.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KEG08239.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEG08239.1 - 0.11 11.7 0.0 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KEG08239.1 - 0.16 12.4 0.3 0.81 10.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 KEG08239.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEG08239.1 - 0.17 11.6 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KEG08239.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KEG08239.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KEG08239.1 - 0.19 11.6 0.4 1.7 8.5 0.0 2.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF5082 PF16888.5 KEG08240.1 - 0.015 15.5 2.2 0.015 15.5 2.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) DUF812 PF05667.11 KEG08241.1 - 8.6e-18 64.5 31.0 4.3e-10 39.1 28.8 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF812) TetR_C_3 PF08362.11 KEG08241.1 - 0.0027 17.7 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region DELLA PF12041.8 KEG08241.1 - 0.047 13.6 0.3 0.51 10.3 0.0 2.8 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Phostensin PF13914.6 KEG08241.1 - 0.058 14.0 2.2 0.69 10.5 0.5 2.5 2 0 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region LXG PF04740.12 KEG08241.1 - 0.31 10.7 14.7 0.23 11.2 0.7 3.6 3 1 0 4 4 4 0 LXG domain of WXG superfamily IFT57 PF10498.9 KEG08241.1 - 0.41 9.5 22.4 0.21 10.5 1.7 3.4 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KEG08241.1 - 2.2 8.4 14.3 1.5 8.9 0.5 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KEG08241.1 - 3.4 7.1 34.6 1.6 8.1 29.2 2.3 1 1 0 2 2 2 0 Golgin subfamily A member 5 SOAR PF16533.5 KEG08241.1 - 3.6 7.6 13.8 16 5.6 13.4 2.4 1 1 0 1 1 1 0 STIM1 Orai1-activating region Sacchrp_dh_NADP PF03435.18 KEG08242.1 - 2.5e-10 40.7 0.0 3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KEG08242.1 - 9.7e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEG08242.1 - 0.00017 21.1 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KEG08242.1 - 0.0023 18.0 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KEG08242.1 - 0.0064 15.9 0.0 0.0078 15.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KEG08242.1 - 0.0075 16.2 0.1 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KEG08242.1 - 0.0077 15.7 0.0 0.0096 15.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KEG08242.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KEG08242.1 - 0.014 14.4 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEG08242.1 - 0.047 14.1 0.0 0.056 13.9 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pre-PUA PF17832.1 KEG08243.1 - 2.6e-17 63.3 0.2 3.8e-17 62.7 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KEG08243.1 - 4.7e-16 58.5 0.1 8.6e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 PUA domain Dzip-like_N PF13815.6 KEG08244.1 - 6.2e-07 29.4 0.1 6.2e-07 29.4 0.1 4.3 3 2 2 5 5 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal VitK2_biosynth PF02621.14 KEG08244.1 - 0.0035 16.9 2.1 0.012 15.1 0.3 2.2 2 0 0 2 2 2 1 Menaquinone biosynthesis 3-PAP PF12578.8 KEG08244.1 - 0.0044 16.8 0.1 0.0044 16.8 0.1 3.4 3 1 0 3 3 3 1 Myotubularin-associated protein DUF883 PF05957.13 KEG08244.1 - 0.0069 17.0 1.4 0.0069 17.0 1.4 3.4 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF883) Rhodanese_C PF12368.8 KEG08244.1 - 0.31 11.5 3.8 1.1 9.7 3.8 1.9 1 0 0 1 1 1 0 Rhodanase C-terminal C1_1 PF00130.22 KEG08244.1 - 0.33 10.9 3.5 0.86 9.5 3.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KEG08244.1 - 0.35 10.9 3.8 1.2 9.2 3.8 2.0 1 0 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 KEG08244.1 - 0.53 9.9 8.1 0.5 10.0 1.0 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF3826 PF12875.7 KEG08244.1 - 0.69 10.0 10.8 3.4 7.8 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) TraG_N PF07916.11 KEG08244.1 - 0.93 8.3 9.1 1.4 7.6 9.1 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region PHD_4 PF16866.5 KEG08244.1 - 0.94 9.6 5.2 3.7 7.7 5.2 2.1 1 0 0 1 1 1 0 PHD-finger Spectrin PF00435.21 KEG08245.1 - 0.13 12.8 6.3 4.9 7.7 0.0 4.0 4 0 0 4 4 4 0 Spectrin repeat CrtC PF07143.11 KEG08247.1 - 2.7e-07 31.4 0.0 1.3e-06 29.2 0.0 2.1 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 KEG08247.1 - 3.1e-05 24.3 0.0 8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Lipocalin-like domain ThiF PF00899.21 KEG08248.1 - 1.4e-77 260.4 0.1 2e-56 191.1 0.1 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KEG08248.1 - 1.2e-62 212.1 0.6 1.8e-62 211.5 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 KEG08248.1 - 5.7e-12 45.7 0.0 2e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle TrkA_N PF02254.18 KEG08248.1 - 0.012 15.9 0.1 0.047 13.9 0.1 2.1 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KEG08248.1 - 0.025 15.0 9.1 0.69 10.4 0.2 4.0 3 1 0 3 3 3 0 Putative NAD(P)-binding Rhamno_transf PF11316.8 KEG08248.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase FAD_binding_3 PF01494.19 KEG08248.1 - 0.057 12.7 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain PhnH PF05845.12 KEG08248.1 - 0.12 12.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnH) 2-Hacid_dh_C PF02826.19 KEG08248.1 - 0.2 11.0 1.7 0.75 9.1 0.1 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tmemb_9 PF05434.11 KEG08250.1 - 0.00073 19.4 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 TMEM9 SID-1_RNA_chan PF13965.6 KEG08250.1 - 0.0012 17.4 0.1 0.0015 17.1 0.1 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Amnionless PF14828.6 KEG08250.1 - 0.0034 16.3 0.0 0.0044 15.9 0.0 1.1 1 0 0 1 1 1 1 Amnionless Comm PF15957.5 KEG08250.1 - 0.005 17.2 0.0 0.009 16.4 0.0 1.4 1 1 0 1 1 1 1 Commissureless Myc_target_1 PF15179.6 KEG08250.1 - 0.011 15.6 0.5 0.017 15.1 0.5 1.3 1 0 0 1 1 1 0 Myc target protein 1 Mtp PF03821.16 KEG08250.1 - 0.017 14.7 0.2 0.021 14.4 0.2 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter EphA2_TM PF14575.6 KEG08250.1 - 0.026 15.4 0.0 0.043 14.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 KEG08250.1 - 0.032 15.2 0.0 0.05 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Phage_Gp23 PF10669.9 KEG08250.1 - 0.045 14.1 0.1 0.058 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) LST1 PF05083.13 KEG08250.1 - 0.049 13.9 0.5 0.076 13.3 0.5 1.3 1 0 0 1 1 1 0 LST-1 protein Shisa PF13908.6 KEG08250.1 - 0.05 13.8 0.0 0.079 13.2 0.0 1.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 KEG08250.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Prominin PF05478.11 KEG08250.1 - 0.084 10.8 0.0 0.087 10.8 0.0 1.2 1 0 0 1 1 1 0 Prominin WBP-1 PF11669.8 KEG08250.1 - 0.091 13.4 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 SCIMP PF15050.6 KEG08250.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein HemY_N PF07219.13 KEG08250.1 - 0.39 10.9 4.9 1.3 9.3 4.8 1.9 1 1 0 1 1 1 0 HemY protein N-terminus TMEM156 PF15106.6 KEG08250.1 - 0.67 9.3 2.3 0.76 9.2 1.6 1.3 1 1 0 1 1 1 0 TMEM156 protein family Phage_holin_2_4 PF16082.5 KEG08251.1 - 0.0048 16.6 0.1 0.008 15.9 0.1 1.3 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like LapA_dom PF06305.11 KEG08251.1 - 0.11 12.3 0.4 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PspB PF06667.12 KEG08252.1 - 0.075 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B NIF PF03031.18 KEG08256.1 - 1e-27 96.9 0.0 1.5e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ClpB_D2-small PF10431.9 KEG08256.1 - 0.089 12.9 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein WD40 PF00400.32 KEG08257.1 - 2.5e-10 40.8 8.1 0.071 14.0 0.1 8.0 10 0 0 10 10 10 4 WD domain, G-beta repeat Syja_N PF02383.18 KEG08261.1 - 2e-33 116.1 0.0 3e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain PSP1 PF04468.12 KEG08263.1 - 0.095 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.25 KEG08264.1 - 2.2e-41 142.2 0.0 2.8e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KEG08264.1 - 0.00041 19.6 0.1 0.00062 19.1 0.1 1.2 1 0 0 1 1 1 1 Tubulin like ThiF PF00899.21 KEG08269.1 - 9.6e-10 38.2 0.0 2.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 ThiF family zf-CCHC_6 PF15288.6 KEG08270.1 - 0.028 14.3 6.1 1.5 8.7 0.7 3.2 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 KEG08270.1 - 0.4 11.1 0.1 0.4 11.1 0.1 3.0 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G KASH_CCD PF14662.6 KEG08271.1 - 0.00027 20.8 24.5 0.00027 20.8 24.5 5.6 3 2 3 6 6 6 1 Coiled-coil region of CCDC155 or KASH GRAB PF10375.9 KEG08271.1 - 0.00097 18.9 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 GRIP-related Arf-binding domain 1-cysPrx_C PF10417.9 KEG08272.1 - 1.1e-14 54.0 0.1 1.7e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 KEG08272.1 - 5.1e-11 42.6 0.0 8.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEG08272.1 - 6.4e-05 22.7 0.0 8.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Rsm1 PF08600.10 KEG08272.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Rsm1-like SKIP_SNW PF02731.15 KEG08273.1 - 2.6e-12 46.7 4.8 2.6e-12 46.7 4.8 3.0 2 1 1 3 3 3 1 SKIP/SNW domain DDHD PF02862.17 KEG08273.1 - 0.86 9.7 7.2 0.25 11.5 4.3 1.6 2 0 0 2 2 2 0 DDHD domain MRP-S31 PF15433.6 KEG08273.1 - 3.4 7.3 13.9 6.8 6.3 13.9 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Presenilin PF01080.17 KEG08273.1 - 4.9 5.8 10.8 1.8 7.3 8.4 1.5 2 0 0 2 2 2 0 Presenilin hDGE_amylase PF14701.6 KEG08273.1 - 5.2 6.1 6.6 7.5 5.5 6.6 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Hid1 PF12722.7 KEG08273.1 - 8.4 4.4 8.6 11 3.9 8.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein polyprenyl_synt PF00348.17 KEG08274.1 - 1.5e-65 220.8 0.1 2.3e-65 220.2 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 KEG08274.1 - 0.0044 16.5 2.5 0.0079 15.7 2.5 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase HrpB2 PF09487.10 KEG08274.1 - 1.5 9.3 4.6 0.65 10.4 0.2 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB2) ELFV_dehydrog PF00208.21 KEG08275.1 - 2.5e-52 178.0 0.0 4.3e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KEG08275.1 - 1.6e-16 59.1 0.1 4e-08 31.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KEG08275.1 - 0.026 14.4 0.2 0.68 9.8 0.0 2.7 3 0 0 3 3 3 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF4453 PF14627.6 KEG08277.1 - 0.026 14.6 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) SET PF00856.28 KEG08286.1 - 1.4e-12 48.4 0.0 3.5e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 SET domain DUF4620 PF15399.6 KEG08286.1 - 0.056 13.8 0.5 0.14 12.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) DNA_pol_B_thumb PF14791.6 KEG08288.1 - 2.7e-19 69.1 0.0 2.5e-18 66.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KEG08288.1 - 9.2e-19 67.7 0.0 2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KEG08288.1 - 4.2e-15 55.8 0.3 3e-13 49.9 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KEG08288.1 - 7.8e-14 51.2 0.0 1.3e-12 47.4 0.0 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KEG08288.1 - 1e-06 29.2 0.3 0.0011 19.5 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix domain IMS_HHH PF11798.8 KEG08288.1 - 0.0045 17.2 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif HHH_3 PF12836.7 KEG08288.1 - 0.0057 16.9 0.1 0.78 10.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 KEG08288.1 - 0.0091 15.7 0.1 4.3 7.2 0.0 3.0 1 1 2 3 3 3 2 Bacterial RNA polymerase, alpha chain C terminal domain EMP70 PF02990.16 KEG08290.1 - 1.3e-157 525.7 14.3 1.9e-157 525.1 14.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Kinesin PF00225.23 KEG08291.1 - 8e-85 284.7 0.0 1.1e-84 284.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08291.1 - 2.3e-25 89.2 0.1 1.3e-24 86.8 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding bZIP_2 PF07716.15 KEG08291.1 - 0.011 15.8 3.2 0.059 13.5 0.4 3.1 2 0 0 2 2 2 0 Basic region leucine zipper NRBF2 PF08961.10 KEG08291.1 - 0.025 14.2 0.2 0.06 13.0 0.2 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator AAA_16 PF13191.6 KEG08291.1 - 0.026 14.9 1.4 0.068 13.5 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KEG08291.1 - 0.031 14.6 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TSC22 PF01166.18 KEG08291.1 - 0.11 12.9 1.2 0.31 11.4 1.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KEG08291.1 - 0.13 12.4 0.3 0.13 12.4 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KEG08291.1 - 3 8.3 16.9 0.28 11.7 0.2 3.8 3 1 0 3 3 3 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 KEG08291.1 - 8.4 6.6 15.6 2.5 8.3 4.0 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Ku PF02735.16 KEG08292.1 - 1.2e-28 100.2 0.0 1.9e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KEG08292.1 - 0.0044 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Agglutinin_C PF18021.1 KEG08296.1 - 0.028 14.9 0.0 0.086 13.4 0.0 1.8 1 0 0 1 1 1 0 Agglutinin C-terminal ABC1 PF03109.16 KEG08297.1 - 1.2e-29 102.9 0.4 4.9e-17 62.2 0.1 2.3 1 1 1 2 2 2 2 ABC1 family Pkinase PF00069.25 KEG08297.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain PSP1 PF04468.12 KEG08298.1 - 1.2e-27 96.0 0.9 1.2e-27 96.0 0.9 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region RBB1NT PF08169.11 KEG08299.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 RBB1NT (NUC162) domain CEP44 PF15007.6 KEG08301.1 - 1.4e-06 28.5 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 YuzL PF14115.6 KEG08304.1 - 0.0083 16.6 0.7 0.025 15.1 0.4 1.9 1 1 1 2 2 2 1 YuzL-like protein Pro_isomerase PF00160.21 KEG08305.1 - 1.6e-45 155.2 0.0 2e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cas_Cas7 PF05107.12 KEG08307.1 - 0.036 13.6 0.5 0.042 13.4 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 zf-RING_9 PF13901.6 KEG08308.1 - 6.2e-21 75.3 18.1 3.4e-17 63.1 2.8 3.3 3 0 0 3 3 3 3 Putative zinc-RING and/or ribbon zf-LSD1 PF06943.12 KEG08309.1 - 1.5e-06 28.0 7.9 1.5e-06 28.0 7.9 2.7 2 1 0 2 2 2 1 LSD1 zinc finger ELO PF01151.18 KEG08310.1 - 1.6e-22 80.3 12.7 2.1e-22 79.9 12.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4661 PF15576.6 KEG08310.1 - 0.076 12.9 0.5 0.12 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) ELO PF01151.18 KEG08311.1 - 1.5e-75 254.0 9.5 1.7e-75 253.8 9.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.8 KEG08311.1 - 0.059 13.4 0.7 3.6 7.6 0.3 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinesin PF00225.23 KEG08312.1 - 5.9e-91 304.8 0.1 2.4e-90 302.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08312.1 - 7.8e-19 68.1 0.2 3.9e-15 56.1 0.1 3.5 3 0 0 3 3 3 2 Microtubule binding Kinesin_assoc PF16183.5 KEG08312.1 - 0.00058 20.1 4.0 0.0018 18.5 4.0 1.9 1 0 0 1 1 1 1 Kinesin-associated DUF4201 PF13870.6 KEG08313.1 - 7.1e-42 143.1 27.8 1.2e-41 142.4 17.3 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) OKR_DC_1_C PF03711.15 KEG08313.1 - 1.4 9.2 4.0 7.2 6.9 0.3 2.4 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain TMF_DNA_bd PF12329.8 KEG08313.1 - 4 7.5 16.4 3.1 7.9 0.1 4.6 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.25 KEG08314.1 - 5.5e-33 114.4 0.0 2.6e-26 92.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08314.1 - 2.4e-06 27.0 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG08314.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_DNAp_acc PF04929.12 KEG08315.1 - 0.41 9.6 3.9 0.46 9.4 3.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DEAD PF00270.29 KEG08316.1 - 1.4e-36 125.9 0.0 6.5e-36 123.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG08316.1 - 3.2e-32 111.2 0.1 1.4e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KEG08316.1 - 0.0073 16.7 0.0 0.52 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KEG08316.1 - 0.015 15.3 0.0 0.065 13.2 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEG08316.1 - 0.057 13.7 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain UvrD_C PF13361.6 KEG08316.1 - 0.11 11.9 0.4 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DnaJ PF00226.31 KEG08317.1 - 3.1e-11 43.2 0.0 7.9e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3446 PF11928.8 KEG08317.1 - 0.037 14.3 7.2 0.1 12.9 7.2 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain IMUP PF15761.5 KEG08317.1 - 5.5 7.7 12.6 13 6.5 12.6 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein U-box PF04564.15 KEG08318.1 - 8.8e-09 35.4 0.5 5.7e-08 32.8 0.0 2.5 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 KEG08318.1 - 2e-05 24.3 0.1 8.7e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 KEG08318.1 - 8.2e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Trans_coact PF16805.5 KEG08318.1 - 0.03 14.4 0.1 4.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Phage late-transcription coactivator FGGY_N PF00370.21 KEG08319.1 - 3.4e-65 220.0 0.0 4.7e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KEG08319.1 - 9e-60 201.8 0.9 1.7e-59 200.9 0.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain EF-hand_13 PF17958.1 KEG08321.1 - 2.4e-22 78.6 0.1 5.5e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KEG08321.1 - 3.2e-15 56.3 0.1 2.1e-11 44.1 0.0 4.4 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG08321.1 - 7.3e-06 25.5 1.9 0.011 15.6 0.0 5.3 5 1 1 6 6 6 1 EF-hand domain EF-hand_1 PF00036.32 KEG08321.1 - 0.00026 20.3 6.0 0.15 11.7 0.0 4.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KEG08321.1 - 0.00053 19.8 2.1 1.3 9.0 0.2 4.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KEG08321.1 - 0.0021 17.5 3.1 0.012 15.1 0.0 3.2 4 0 0 4 4 4 1 EF hand Thioredoxin PF00085.20 KEG08322.1 - 3.4e-09 36.6 0.0 5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Caskin-Pro-rich PF16907.5 KEG08322.1 - 0.29 11.7 3.8 0.27 11.8 1.7 1.9 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Cys_Met_Meta_PP PF01053.20 KEG08323.1 - 1.2e-125 419.0 0.2 1.4e-125 418.8 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEG08323.1 - 2e-11 43.8 2.9 5.3e-11 42.4 1.7 1.9 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KEG08323.1 - 4.8e-08 32.6 0.1 6.5e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEG08323.1 - 4.1e-06 26.0 0.1 6.9e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEG08323.1 - 9.7e-05 21.8 0.2 0.00017 21.0 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF5082 PF16888.5 KEG08324.1 - 0.038 14.3 1.9 0.038 14.3 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 KEG08324.1 - 0.048 12.5 6.5 0.076 11.9 6.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Mod_r PF07200.13 KEG08324.1 - 0.12 12.5 6.5 0.33 11.0 6.1 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 KEG08324.1 - 0.16 11.3 13.1 0.39 10.0 13.1 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 KEG08324.1 - 0.24 11.7 8.3 0.27 11.6 4.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 KEG08324.1 - 1 9.8 14.8 0.4 11.1 12.5 1.4 2 0 0 2 2 2 0 Fez1 YabA PF06156.13 KEG08324.1 - 1.6 9.4 8.7 11 6.7 8.7 2.6 1 1 0 1 1 1 0 Initiation control protein YabA YlqD PF11068.8 KEG08324.1 - 2.3 8.6 10.6 2.2 8.7 8.6 1.8 2 0 0 2 2 2 0 YlqD protein FUSC PF04632.12 KEG08324.1 - 4.7 5.6 16.5 6.2 5.2 16.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_M8 PF01457.16 KEG08325.1 - 8.7e-42 143.5 0.1 9.2e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Zip PF02535.22 KEG08327.1 - 0.0022 17.2 2.9 0.0024 17.1 2.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PQ-loop PF04193.14 KEG08328.1 - 4.5e-32 109.6 19.5 1.2e-16 60.2 3.0 3.2 3 0 0 3 3 3 2 PQ loop repeat Zip PF02535.22 KEG08330.1 - 1.8e-30 106.3 12.6 3.3e-30 105.5 12.6 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4267 PF14087.6 KEG08330.1 - 1.8 8.7 8.0 15 5.7 8.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) PQ-loop PF04193.14 KEG08331.1 - 1.5e-30 104.7 14.2 1.5e-16 59.9 3.6 3.2 4 0 0 4 4 4 2 PQ loop repeat NTP_transf_3 PF12804.7 KEG08333.1 - 1.3e-05 25.6 0.2 0.00078 19.8 0.1 2.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KEG08333.1 - 0.00019 21.1 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KEG08333.1 - 0.0025 16.0 1.6 0.0039 15.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KEG08333.1 - 0.055 12.4 0.2 0.11 11.4 0.2 1.5 1 0 0 1 1 1 0 L-fucokinase PBP1_TM PF14812.6 KEG08333.1 - 0.12 12.8 11.6 0.45 10.9 5.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hexapep PF00132.24 KEG08333.1 - 0.16 11.7 18.0 0.71 9.7 3.8 3.9 1 1 3 4 4 4 0 Bacterial transferase hexapeptide (six repeats) DUF4611 PF15387.6 KEG08333.1 - 1.6 9.0 7.3 6.6 7.0 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3246 PF11596.8 KEG08333.1 - 3.7 6.9 5.1 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) RNase_E_G PF10150.9 KEG08334.1 - 0.079 12.4 10.5 0.48 9.8 3.7 2.2 1 1 1 2 2 2 0 Ribonuclease E/G family HALZ PF02183.18 KEG08334.1 - 0.095 12.9 1.5 0.095 12.9 1.5 3.4 3 1 0 3 3 3 0 Homeobox associated leucine zipper Cep57_MT_bd PF06657.13 KEG08335.1 - 0.0047 17.4 1.0 0.0061 17.0 0.1 1.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 KEG08335.1 - 0.014 15.8 1.1 0.018 15.4 1.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Zwint PF15556.6 KEG08335.1 - 0.027 14.0 0.9 0.032 13.7 0.9 1.1 1 0 0 1 1 1 0 ZW10 interactor FANCD2OS PF15124.6 KEG08335.1 - 0.028 14.6 0.3 0.053 13.7 0.2 1.5 1 1 0 1 1 1 0 FANCD2 opposite strand protein DUF724 PF05266.14 KEG08335.1 - 0.1 12.4 1.1 0.13 12.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PCI PF01399.27 KEG08336.1 - 1.2e-09 38.6 0.0 2.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.10 KEG08336.1 - 1.1e-06 29.2 3.3 3e-06 27.7 0.8 2.7 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain Med15 PF09606.10 KEG08337.1 - 0.00011 21.1 25.8 0.00014 20.8 25.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 KEG08337.1 - 0.00056 20.0 10.8 0.0011 19.1 10.8 1.5 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.8 KEG08337.1 - 0.0035 17.0 30.1 0.0035 17.0 30.1 1.8 2 0 0 2 2 2 1 Spt20 family SAPS PF04499.15 KEG08337.1 - 0.03 13.1 10.3 0.039 12.7 10.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.13 KEG08337.1 - 0.066 12.8 17.4 0.12 12.0 17.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2052 PF09747.9 KEG08337.1 - 0.82 9.8 26.5 0.57 10.3 12.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) AAA_22 PF13401.6 KEG08337.1 - 1 9.6 7.1 2.9 8.2 7.1 1.7 1 1 0 1 1 1 0 AAA domain DUF3464 PF11947.8 KEG08337.1 - 2.4 7.9 21.6 0.086 12.6 11.9 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 XRCC4 PF06632.12 KEG08337.1 - 2.6 6.8 21.6 4.7 6.0 21.6 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Eapp_C PF10238.9 KEG08337.1 - 3 7.9 22.2 1 9.4 11.2 2.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein Peroxin-3 PF04882.12 KEG08337.1 - 3.1 6.7 18.0 6.7 5.6 18.0 1.5 1 0 0 1 1 1 0 Peroxin-3 MMR1 PF08505.10 KEG08337.1 - 3.1 8.0 21.2 0.05 13.9 9.2 3.0 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein TERB2 PF15101.6 KEG08337.1 - 4.3 7.3 23.3 0.37 10.8 14.8 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 GREB1 PF15782.5 KEG08337.1 - 5.1 4.1 18.6 6.7 3.7 18.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer U1snRNP70_N PF12220.8 KEG08337.1 - 5.6 7.7 23.5 5.6 7.7 1.5 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF775 PF05603.12 KEG08337.1 - 6.5 6.2 10.3 16 5.0 10.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Glyco_hydro_32N PF00251.20 KEG08339.1 - 9.5e-25 87.8 1.6 1.3e-24 87.3 1.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KEG08339.1 - 4e-13 49.7 0.0 2e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.6 KEG08339.1 - 0.014 15.3 0.4 0.033 14.1 0.4 1.6 1 0 0 1 1 1 0 PAN domain PTP_tm PF18861.1 KEG08341.1 - 0.00021 21.3 0.9 0.00039 20.5 0.9 1.4 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD34_antigen PF06365.12 KEG08341.1 - 0.041 13.5 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Mic1 PF07035.12 KEG08342.1 - 2e-07 30.9 0.3 3.8e-07 29.9 0.3 1.4 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like ERbeta_N PF12497.8 KEG08342.1 - 0.44 10.3 2.7 1.1 9.1 2.7 1.6 1 0 0 1 1 1 0 Estrogen receptor beta DnaJ PF00226.31 KEG08343.1 - 6.5e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TraX PF05857.11 KEG08343.1 - 0.017 15.2 1.3 0.024 14.7 1.3 1.2 1 0 0 1 1 1 0 TraX protein FliD_N PF02465.18 KEG08344.1 - 0.045 14.4 1.2 0.11 13.2 1.2 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4229 PF14012.6 KEG08344.1 - 0.26 11.4 5.1 0.97 9.6 5.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Jnk-SapK_ap_N PF09744.9 KEG08345.1 - 0.076 13.2 1.5 0.11 12.7 1.5 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PcrB PF01884.17 KEG08346.1 - 0.25 10.7 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 PcrB family Skp1 PF01466.19 KEG08348.1 - 1.2e-06 28.5 0.1 2.4e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain IGF2_C PF08365.11 KEG08350.1 - 0.087 12.9 0.7 1.8 8.6 0.4 2.3 2 1 0 2 2 2 0 Insulin-like growth factor II E-peptide IRK_C PF17655.1 KEG08352.1 - 8.1e-08 32.1 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain DHHA1 PF02272.19 KEG08352.1 - 0.43 11.0 2.4 0.93 9.9 2.4 1.5 1 0 0 1 1 1 0 DHHA1 domain SOG2 PF10428.9 KEG08352.1 - 2.2 7.4 15.0 3.1 6.9 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 KEG08352.1 - 7.2 5.3 7.3 9.3 4.9 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Metallophos PF00149.28 KEG08353.1 - 2.6e-23 83.6 0.0 3.9e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2046 PF09755.9 KEG08353.1 - 0.024 13.9 0.5 0.024 13.9 0.5 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) GP57 PF17594.2 KEG08354.1 - 0.09 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 RPN2_C PF18004.1 KEG08354.1 - 0.1 12.5 0.4 0.23 11.4 0.4 1.6 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TauE PF01925.19 KEG08356.1 - 0.065 12.9 3.4 0.091 12.4 3.4 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE TruD PF01142.18 KEG08357.1 - 0.044 12.6 0.0 1.9 7.2 0.0 3.1 4 0 0 4 4 4 0 tRNA pseudouridine synthase D (TruD) zf-HC5HC2H PF13771.6 KEG08358.1 - 3.2e-06 27.3 3.5 3.2e-06 27.3 3.5 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KEG08358.1 - 0.0092 16.1 8.0 0.0092 16.1 8.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain NIF PF03031.18 KEG08359.1 - 1.8e-29 102.5 0.2 3e-29 101.8 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 KEG08359.1 - 0.026 14.0 0.4 0.035 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) HAD PF12710.7 KEG08359.1 - 0.069 13.6 0.0 1.4 9.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_tranf_2_4 PF13704.6 KEG08359.1 - 0.091 13.3 3.1 1.3 9.6 0.1 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 2 MSA-2c PF12238.8 KEG08359.1 - 5 7.1 4.8 9.9 6.1 4.8 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c EF-hand_9 PF14658.6 KEG08360.1 - 2.5e-10 40.5 0.4 7.5e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KEG08360.1 - 5.1e-08 33.2 0.4 0.0037 17.7 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG08360.1 - 1.6e-05 24.5 0.0 1 9.4 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_14 PF17959.1 KEG08360.1 - 0.0081 16.5 0.0 0.033 14.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF3507 PF12015.8 KEG08360.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3507) EF-hand_8 PF13833.6 KEG08360.1 - 0.04 13.8 0.3 0.28 11.1 0.1 2.6 2 1 0 2 2 2 0 EF-hand domain pair IQ PF00612.27 KEG08361.1 - 1.6e-29 98.9 176.7 2.2e-05 23.8 1.5 25.6 25 1 0 25 25 25 18 IQ calmodulin-binding motif TPR_12 PF13424.6 KEG08361.1 - 1.6e-06 28.3 13.7 1.5e-05 25.2 0.8 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEG08361.1 - 4.4e-05 23.2 0.3 4.4e-05 23.2 0.3 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG08361.1 - 0.00022 20.9 6.7 0.028 14.2 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG08361.1 - 0.00078 19.4 11.3 0.32 11.2 0.2 6.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG08361.1 - 0.0013 18.8 3.3 0.37 11.1 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG08361.1 - 0.034 14.2 0.1 40 4.6 0.0 4.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Tau95 PF09734.9 KEG08362.1 - 7.7e-20 72.1 0.0 1.7e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KEG08362.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Tau95 Triple barrel domain zf-LSD1 PF06943.12 KEG08364.1 - 2.1 8.3 6.4 8 6.4 0.2 2.8 2 0 0 2 2 2 0 LSD1 zinc finger Glyco_hydro_85 PF03644.13 KEG08367.1 - 3e-78 263.3 0.0 4.8e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.14 KEG08367.1 - 4.3e-24 85.1 0.0 7.4e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 KEG08367.1 - 7.8e-15 54.6 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain LRAT PF04970.13 KEG08367.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Glyco_hydro_18 PF00704.28 KEG08367.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 LAP1C PF05609.12 KEG08369.1 - 0.21 10.6 10.8 0.29 10.2 10.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 KEG08369.1 - 2.4 6.2 9.9 3 5.8 9.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Avl9 PF09794.9 KEG08370.1 - 6.1e-05 21.9 0.0 0.00032 19.5 0.0 2.0 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KEG08370.1 - 0.0013 18.6 0.1 0.0046 16.9 0.1 1.9 1 1 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 KEG08370.1 - 0.035 14.1 6.7 11 6.0 6.7 2.9 1 1 0 1 1 1 0 DENN (AEX-3) domain Afi1 PF07792.12 KEG08370.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Acetyltransf_1 PF00583.25 KEG08371.1 - 0.0081 16.4 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG08371.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_trans_1_2 PF13524.6 KEG08371.1 - 0.14 12.6 1.1 21 5.6 0.3 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 DnaJ PF00226.31 KEG08372.1 - 3e-21 75.3 0.2 5.6e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KEG08372.1 - 2.7e-05 24.4 0.2 5.3e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Mobilization_B PF17511.2 KEG08372.1 - 0.16 12.4 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Mobilization protein B PglZ PF08665.12 KEG08374.1 - 0.072 13.2 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 PglZ domain DUF5521 PF17659.1 KEG08374.1 - 0.38 8.6 1.1 0.47 8.2 1.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DnaJ_C PF01556.18 KEG08376.1 - 2.1e-30 105.7 0.0 2.8e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG08376.1 - 1.4e-18 66.7 0.5 3e-18 65.7 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEG08376.1 - 4e-14 52.7 16.3 6.7e-14 52.0 16.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEG08376.1 - 1.5e-08 34.5 7.4 9.4e-05 22.3 0.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KEG08376.1 - 0.23 11.5 9.9 0.71 9.9 10.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KEG08376.1 - 0.26 11.3 10.4 0.73 9.9 2.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KEG08376.1 - 0.91 9.2 9.2 0.34 10.5 1.1 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF3797 PF12677.7 KEG08376.1 - 0.92 9.5 3.8 2.6 8.0 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Lar_restr_allev PF14354.6 KEG08376.1 - 3.1 8.2 8.6 16 5.9 0.5 3.5 2 1 1 3 3 3 0 Restriction alleviation protein Lar Pyr_redox_2 PF07992.14 KEG08377.1 - 1.4e-68 231.3 5.2 1.4e-68 231.3 5.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEG08377.1 - 4.2e-39 133.2 0.7 1.4e-38 131.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEG08377.1 - 1.6e-19 70.2 5.1 3.5e-16 59.5 0.4 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG08377.1 - 1.6e-12 47.3 3.3 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEG08377.1 - 6.1e-11 42.3 0.7 6.1e-11 42.3 0.7 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KEG08377.1 - 1.3e-08 34.4 12.8 7.9e-07 28.5 7.4 3.0 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEG08377.1 - 2.6e-08 33.4 10.6 1.1e-07 31.3 2.4 3.3 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KEG08377.1 - 4e-07 30.2 5.7 4.3e-05 23.7 0.8 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KEG08377.1 - 7.3e-07 28.7 5.3 0.0011 18.3 0.2 2.8 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KEG08377.1 - 6.2e-05 22.3 0.3 0.027 13.6 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEG08377.1 - 0.0001 21.6 1.6 0.00033 20.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEG08377.1 - 0.0002 20.2 1.1 0.0002 20.2 1.1 4.2 4 1 1 5 5 5 1 HI0933-like protein FAD_binding_3 PF01494.19 KEG08377.1 - 0.00023 20.5 13.1 0.015 14.6 1.0 3.2 2 1 1 3 3 3 3 FAD binding domain 3HCDH_N PF02737.18 KEG08377.1 - 0.0072 16.2 2.3 0.014 15.3 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KEG08377.1 - 0.041 14.3 3.1 0.92 10.0 0.1 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KEG08377.1 - 0.074 12.1 4.3 0.95 8.4 0.6 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 KEG08377.1 - 0.079 13.2 0.7 0.24 11.7 0.0 2.2 2 0 0 2 2 1 0 TrkA-N domain XdhC_C PF13478.6 KEG08377.1 - 0.081 13.4 0.1 4 8.0 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 KEG08377.1 - 0.24 10.9 16.0 0.22 11.1 1.5 3.3 3 1 1 4 4 4 0 FAD dependent oxidoreductase Cyclin_N PF00134.23 KEG08378.1 - 3.8e-38 130.1 0.5 1.4e-37 128.3 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEG08378.1 - 5.3e-29 100.7 0.2 1.3e-28 99.5 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain EF-hand_6 PF13405.6 KEG08379.1 - 2.6e-16 58.1 6.7 6.3e-05 22.6 0.3 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KEG08379.1 - 1.5e-15 57.4 0.4 8.5e-09 35.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG08379.1 - 2.7e-14 51.5 3.8 5.1e-06 25.7 0.0 4.9 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KEG08379.1 - 1.6e-08 34.2 7.8 0.00049 19.9 0.5 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KEG08379.1 - 2.1e-08 33.3 0.3 8.3e-05 21.9 0.0 5.1 5 1 0 5 5 5 2 EF hand EF-hand_10 PF14788.6 KEG08379.1 - 0.015 15.1 0.8 16 5.4 0.1 3.2 3 0 0 3 3 3 0 EF hand MazG_C PF18722.1 KEG08379.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 MazG C-terminal domain SPARC_Ca_bdg PF10591.9 KEG08379.1 - 0.063 13.6 0.9 0.43 10.9 0.2 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PSK_trans_fac PF07704.11 KEG08380.1 - 0.65 10.8 3.3 2.2 9.1 0.7 3.2 2 0 0 2 2 2 0 Rv0623-like transcription factor Aa_trans PF01490.18 KEG08381.1 - 7.7e-46 156.6 36.3 1.5e-45 155.7 36.3 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Lipase_3 PF01764.25 KEG08384.1 - 2.9e-26 92.0 0.0 4.1e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KEG08384.1 - 0.00034 20.8 0.2 0.00062 20.0 0.2 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KEG08384.1 - 0.0033 16.7 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 KEG08384.1 - 0.024 14.2 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KEG08384.1 - 0.027 15.1 0.2 0.035 14.7 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 KEG08384.1 - 0.16 11.0 0.2 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Esterase PF00756.20 KEG08384.1 - 0.4 10.3 3.4 0.68 9.5 3.4 1.6 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KEG08385.1 - 2.3e-09 37.2 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_M8 PF01457.16 KEG08386.1 - 3.4e-132 441.8 0.0 4.5e-132 441.4 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Astacin PF01400.24 KEG08386.1 - 0.018 14.6 0.2 0.034 13.8 0.2 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KEG08386.1 - 0.087 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Matrixin BatA PF07584.11 KEG08388.1 - 0.013 15.9 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal SH2_2 PF14633.6 KEG08389.1 - 9.2e-17 61.2 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 KEG08389.1 - 7.7e-14 51.7 0.0 3.6e-13 49.5 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 FYDLN_acid PF09538.10 KEG08389.1 - 0.92 10.2 17.3 0.48 11.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cuticle_2 PF08184.11 KEG08389.1 - 0.99 9.5 4.3 39 4.3 0.0 3.7 4 0 0 4 4 4 0 Cuticle protein 7 isoform family PqiA PF04403.13 KEG08391.1 - 4e-10 39.7 8.2 4e-10 39.7 8.2 3.0 2 1 0 2 2 2 1 Paraquat-inducible protein A LBP_BPI_CETP PF01273.25 KEG08391.1 - 0.0014 18.2 0.8 0.0045 16.6 0.8 1.9 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain RRM_1 PF00076.22 KEG08392.1 - 3.2e-59 196.7 0.0 9.4e-20 70.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KEG08392.1 - 8e-23 80.4 0.6 3.9e-22 78.2 0.3 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 KEG08392.1 - 2e-06 27.7 0.0 9.2 6.4 0.0 4.5 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 KEG08392.1 - 0.0054 16.7 0.0 3.2 7.8 0.0 3.7 4 0 0 4 4 4 1 RNA binding domain Snf7 PF03357.21 KEG08394.1 - 0.056 13.0 0.5 0.074 12.6 0.5 1.1 1 0 0 1 1 1 0 Snf7 Peptidase_M8 PF01457.16 KEG08395.1 - 9e-145 483.3 3.2 1.2e-144 483.0 3.2 1.1 1 0 0 1 1 1 1 Leishmanolysin Astacin PF01400.24 KEG08395.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) HRM PF02793.22 KEG08395.1 - 0.12 12.7 1.2 1.2 9.5 0.3 2.6 2 0 0 2 2 2 0 Hormone receptor domain AAA PF00004.29 KEG08398.1 - 1.9e-34 118.9 0.0 5.6e-31 107.7 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEG08398.1 - 4.6e-11 43.1 0.7 3.2e-07 30.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEG08398.1 - 5.5e-11 42.9 0.7 0.0004 20.7 0.8 3.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEG08398.1 - 1.6e-10 41.6 5.4 0.00015 22.2 0.6 4.0 2 2 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KEG08398.1 - 1.1e-09 38.3 0.0 0.00062 19.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 KEG08398.1 - 2.8e-07 30.6 0.0 0.001 19.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KEG08398.1 - 1.3e-06 27.8 0.0 0.0041 16.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 KEG08398.1 - 1.3e-05 24.7 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KEG08398.1 - 1.8e-05 24.8 0.0 0.0002 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KEG08398.1 - 2.5e-05 23.7 0.0 0.2 10.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TniB PF05621.11 KEG08398.1 - 3.4e-05 23.3 0.0 0.0096 15.3 0.0 3.3 3 1 1 4 4 4 1 Bacterial TniB protein AAA_18 PF13238.6 KEG08398.1 - 0.00016 22.2 0.0 0.021 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEG08398.1 - 0.00032 21.1 0.0 0.46 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KEG08398.1 - 0.00035 20.0 0.0 0.025 14.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KEG08398.1 - 0.00068 20.2 0.0 0.87 10.1 0.0 2.9 3 0 0 3 3 2 1 ABC transporter RuvB_N PF05496.12 KEG08398.1 - 0.00068 19.4 0.0 0.0036 17.1 0.0 2.2 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KEG08398.1 - 0.0013 18.4 0.0 0.42 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KEG08398.1 - 0.0014 18.6 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KEG08398.1 - 0.0014 18.9 1.2 0.8 10.0 0.2 3.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KEG08398.1 - 0.0015 17.8 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 KEG08398.1 - 0.0045 17.1 0.0 0.096 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 KEG08398.1 - 0.0048 16.9 0.0 1.8 8.4 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KEG08398.1 - 0.0055 16.6 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KEG08398.1 - 0.0056 16.7 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEG08398.1 - 0.008 15.9 1.3 3.1 7.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KEG08398.1 - 0.01 15.6 0.0 2.4 7.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AFG1_ATPase PF03969.16 KEG08398.1 - 0.014 14.3 0.0 0.29 10.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.6 KEG08398.1 - 0.016 14.9 0.0 10 5.9 0.0 3.0 2 1 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KEG08398.1 - 0.016 14.8 1.3 0.82 9.2 0.1 3.1 3 1 0 3 3 3 0 AAA domain MCM PF00493.23 KEG08398.1 - 0.019 14.1 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain KTI12 PF08433.10 KEG08398.1 - 0.023 14.2 0.0 0.19 11.1 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 KEG08398.1 - 0.03 13.6 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 KEG08398.1 - 0.034 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.15 KEG08398.1 - 0.046 13.6 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PhoH PF02562.16 KEG08398.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein APS_kinase PF01583.20 KEG08398.1 - 0.14 12.0 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase WD40 PF00400.32 KEG08400.1 - 6.1e-14 52.2 14.3 1e-06 29.3 0.7 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG08400.1 - 2.5e-06 27.7 0.0 0.00051 20.3 0.0 2.4 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG08400.1 - 0.014 14.3 0.0 3.3 6.6 0.0 2.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KEG08400.1 - 0.092 11.3 0.1 0.23 9.9 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain DAGK_cat PF00781.24 KEG08400.1 - 0.29 10.7 0.6 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF3240 PF11582.8 KEG08401.1 - 0.055 13.6 0.0 6.7 6.9 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3240) F-box-like PF12937.7 KEG08402.1 - 1.3e-06 28.2 1.0 2.8e-06 27.1 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEG08402.1 - 0.00012 21.8 0.2 0.00024 20.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain NAD_binding_9 PF13454.6 KEG08403.1 - 0.22 11.5 2.6 0.34 10.9 2.6 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding His_Phos_2 PF00328.22 KEG08404.1 - 2.3e-13 50.2 0.8 2.2e-08 33.9 0.0 3.1 2 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 KEG08405.1 - 9.2e-44 149.8 0.3 9.1e-43 146.5 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08405.1 - 1.3e-18 67.2 0.0 7.9e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KEG08405.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG08405.1 - 0.027 14.4 0.0 0.12 12.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KEG08405.1 - 0.039 13.5 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Thioredoxin_7 PF13899.6 KEG08406.1 - 0.00039 20.5 0.1 0.0022 18.1 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like NTP_transf_9 PF04248.12 KEG08406.1 - 0.0008 19.2 0.1 0.015 15.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF427) Thioredoxin_2 PF13098.6 KEG08406.1 - 0.033 14.7 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain PQ-loop PF04193.14 KEG08407.1 - 5.8e-27 93.2 2.8 6.3e-15 54.7 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat LisH_2 PF16045.5 KEG08407.1 - 0.03 13.3 0.1 0.054 12.5 0.1 1.4 1 0 0 1 1 1 0 LisH HCV_NS1 PF01560.17 KEG08407.1 - 0.079 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 PaO PF08417.12 KEG08407.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Pheophorbide a oxygenase OapA_N PF08525.11 KEG08410.1 - 0.00033 20.5 4.5 4 7.5 0.2 3.3 3 0 0 3 3 3 3 Opacity-associated protein A N-terminal motif DUF1079 PF06435.11 KEG08415.1 - 0.0078 16.4 0.6 0.0078 16.4 0.6 3.6 3 0 0 3 3 3 1 Repeat of unknown function (DUF1079) DUF5636 PF18686.1 KEG08415.1 - 0.045 13.9 0.8 0.045 13.9 0.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5636) T3SS_needle_F PF09392.10 KEG08417.1 - 0.1 12.8 6.9 0.87 9.8 1.7 3.5 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Polo_box_3 PF18544.1 KEG08417.1 - 3.9 8.2 7.8 5.6 7.7 0.2 2.9 3 0 0 3 3 3 0 Polo box domain IHO1 PF15771.5 KEG08418.1 - 0.025 13.4 9.3 0.028 13.2 9.3 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 ANAPC_CDC26 PF10471.9 KEG08418.1 - 2.6 8.9 8.0 15 6.5 8.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF3450 PF11932.8 KEG08419.1 - 0.00073 18.9 4.8 0.00089 18.6 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) SesA PF17107.5 KEG08419.1 - 0.0027 17.9 4.4 0.24 11.6 0.2 2.2 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases Blo-t-5 PF11642.8 KEG08419.1 - 0.0074 16.2 2.1 0.012 15.6 2.1 1.4 1 0 0 1 1 1 1 Mite allergen Blo t 5 PriC PF07445.12 KEG08419.1 - 0.009 15.9 7.7 0.013 15.4 7.7 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC IFT57 PF10498.9 KEG08419.1 - 0.044 12.8 3.5 0.11 11.5 0.3 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 End3 PF12761.7 KEG08419.1 - 0.045 13.9 3.3 0.075 13.2 3.3 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 T2SSF PF00482.23 KEG08419.1 - 0.068 13.1 0.5 1.6 8.7 0.0 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F CAGE1 PF15066.6 KEG08419.1 - 0.11 11.2 5.9 0.17 10.5 0.8 2.0 1 1 0 2 2 2 0 Cancer-associated gene protein 1 family CENP-Q PF13094.6 KEG08419.1 - 0.13 12.4 16.2 0.04 14.1 10.0 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FH2 PF02181.23 KEG08419.1 - 0.13 11.3 1.3 0.16 11.0 1.3 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Sec2p PF06428.11 KEG08419.1 - 0.24 11.4 8.9 1.1 9.3 2.5 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 KEG08419.1 - 0.29 11.5 2.7 2 8.9 0.1 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 KEG08419.1 - 0.3 10.6 3.2 0.36 10.4 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PEP-utilisers_N PF05524.13 KEG08419.1 - 0.31 11.2 6.1 0.58 10.3 5.9 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF5344 PF17279.2 KEG08419.1 - 0.44 11.2 3.3 2.3 8.9 3.3 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5344) Ntox28 PF15605.6 KEG08419.1 - 0.46 10.8 3.0 0.64 10.3 1.2 2.1 2 1 0 2 2 2 0 Bacterial toxin 28 DUF1664 PF07889.12 KEG08419.1 - 0.48 10.5 1.8 1.1 9.2 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FPP PF05911.11 KEG08419.1 - 0.53 8.4 10.5 0.35 9.0 3.9 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF724 PF05266.14 KEG08419.1 - 0.59 9.9 5.8 1.6 8.5 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 KEG08419.1 - 2 8.7 5.3 3 8.1 1.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SLATT_fungal PF18142.1 KEG08419.1 - 2.1 8.3 4.1 14 5.7 0.1 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Lzipper-MIP1 PF14389.6 KEG08419.1 - 2.1 8.7 11.3 6.8 7.1 7.3 2.7 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Csm1_N PF18504.1 KEG08419.1 - 4.8 7.6 10.1 3 8.2 2.8 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain Swi5 PF07061.11 KEG08419.1 - 6.6 6.9 10.0 17 5.5 3.3 2.4 1 1 1 2 2 2 0 Swi5 DUF1087 PF06465.13 KEG08420.1 - 0.0053 16.7 0.3 29 4.8 0.0 3.3 1 1 2 3 3 3 3 Domain of Unknown Function (DUF1087) MT PF12777.7 KEG08421.1 - 1.6e-08 34.0 0.0 4.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor IFT57 PF10498.9 KEG08421.1 - 0.03 13.3 43.9 0.018 14.0 2.9 4.7 4 1 1 5 5 5 0 Intra-flagellar transport protein 57 TFIIS_C PF01096.18 KEG08421.1 - 0.13 12.2 1.1 22 5.0 0.1 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Spc29 PF17082.5 KEG08421.1 - 1.8 8.4 26.2 10 5.9 4.5 4.5 2 1 2 4 4 4 0 Spindle Pole Component 29 FPP PF05911.11 KEG08421.1 - 2.1 6.4 58.8 0.079 11.1 10.4 5.0 3 1 2 5 5 5 0 Filament-like plant protein, long coiled-coil Prefoldin PF02996.17 KEG08422.1 - 4e-09 36.4 0.0 7.8e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Prefoldin subunit Torsin PF06309.11 KEG08424.1 - 2e-05 24.7 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA PF00004.29 KEG08424.1 - 0.00071 20.0 0.0 0.0046 17.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SpmSyn_N PF17950.1 KEG08424.1 - 0.013 15.6 0.4 7.3 6.9 0.0 2.6 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal AAA_21 PF13304.6 KEG08424.1 - 0.02 14.7 0.4 5.7 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CAP_N PF01213.19 KEG08424.1 - 0.037 13.5 0.9 0.057 12.9 0.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_5 PF07728.14 KEG08424.1 - 0.15 12.0 0.0 5.7 6.9 0.0 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1726 PF08351.11 KEG08424.1 - 0.16 11.9 0.1 27 4.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Sigma54_activ_2 PF14532.6 KEG08424.1 - 0.18 11.9 0.0 0.86 9.7 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain HEAT PF02985.22 KEG08425.1 - 0.1 12.9 0.4 3.2 8.3 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat FixO PF02433.15 KEG08426.1 - 0.041 13.3 0.2 0.077 12.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO NAD_binding_5 PF07994.12 KEG08427.1 - 3.8e-134 447.1 0.0 4.4e-134 446.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KEG08427.1 - 2.5e-44 150.0 0.0 5.1e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FA_desaturase PF00487.24 KEG08428.1 - 2.6e-32 112.6 18.6 2.6e-32 112.6 18.6 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEG08428.1 - 0.00036 20.6 0.0 0.00074 19.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 KEG08429.1 - 0.0002 22.1 6.6 0.88 10.6 0.3 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat LisH PF08513.11 KEG08429.1 - 0.0034 17.3 2.5 0.063 13.3 0.5 2.4 2 0 0 2 2 2 1 LisH ANAPC4_WD40 PF12894.7 KEG08429.1 - 0.0097 16.2 0.2 2.1 8.7 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KEG08429.1 - 0.15 11.3 0.0 2.3 7.4 0.0 2.2 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-RING_2 PF13639.6 KEG08430.1 - 1e-07 32.2 25.5 1.1e-07 32.1 9.5 2.7 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 KEG08430.1 - 8.4e-07 28.8 7.0 8.4e-07 28.8 7.0 3.0 3 1 0 3 3 2 1 PHD-finger zf-C3HC4 PF00097.25 KEG08430.1 - 8.4e-06 25.6 8.7 8.4e-06 25.6 8.7 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG08430.1 - 1e-05 25.4 8.7 1e-05 25.4 8.7 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEG08430.1 - 6e-05 22.8 8.7 6e-05 22.8 8.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEG08430.1 - 7e-05 23.0 7.7 7e-05 23.0 7.7 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KEG08430.1 - 0.00033 20.5 6.0 0.00033 20.5 6.0 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG08430.1 - 0.0034 17.4 3.8 0.0034 17.4 3.8 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KEG08430.1 - 0.0049 16.7 9.4 0.0049 16.7 9.4 3.4 2 2 1 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEG08430.1 - 0.005 16.8 8.0 0.005 16.8 8.0 3.0 2 0 0 2 2 2 1 RING-type zinc-finger C1_2 PF03107.16 KEG08430.1 - 0.014 15.7 2.9 0.014 15.7 2.9 3.3 3 1 1 4 4 2 0 C1 domain DZR PF12773.7 KEG08430.1 - 0.015 15.3 6.2 0.015 15.3 6.2 3.1 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.6 KEG08430.1 - 0.024 14.4 23.0 0.86 9.5 6.4 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 KEG08430.1 - 0.044 14.0 1.5 0.044 14.0 1.5 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.6 KEG08430.1 - 0.22 11.7 14.9 0.32 11.2 5.3 3.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KEG08430.1 - 1.4 9.1 18.0 0.041 14.0 2.9 2.7 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-H2C2_2 PF13465.6 KEG08430.1 - 2 9.0 7.9 1.3 9.6 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.25 KEG08431.1 - 1.3e-61 208.3 0.0 1.5e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08431.1 - 6.9e-26 91.1 0.0 1.6e-25 89.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG08431.1 - 0.0087 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG08431.1 - 0.021 14.8 0.3 0.068 13.1 0.3 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KEG08431.1 - 0.049 13.3 0.0 7.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Plus-3 PF03126.18 KEG08432.1 - 0.0062 17.0 0.1 0.021 15.3 0.1 2.0 1 0 0 1 1 1 1 Plus-3 domain Clathrin PF00637.20 KEG08433.1 - 5.1e-05 23.2 0.1 0.00014 21.7 0.1 1.7 1 1 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.9 KEG08433.1 - 0.00039 20.8 0.1 0.0031 18.0 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-HC5HC2H_2 PF13832.6 KEG08433.1 - 0.023 14.9 0.3 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 KEG08433.1 - 0.07 12.8 2.3 0.088 12.5 0.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type HSP70 PF00012.20 KEG08435.1 - 5.3e-248 824.1 2.8 6.1e-248 823.9 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEG08435.1 - 9.8e-18 64.0 0.6 3.8e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KEG08435.1 - 0.0033 17.8 1.6 7.3 7.1 0.1 3.6 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KEG08435.1 - 0.01 15.3 0.1 4.7 6.6 0.1 2.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NUC153 PF08159.12 KEG08436.1 - 5.6e-05 22.9 0.0 0.00018 21.2 0.0 1.9 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KEG08436.1 - 0.09 13.7 0.7 11 7.1 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat XRCC4 PF06632.12 KEG08436.1 - 3.2 6.5 10.0 6.6 5.5 10.0 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Nop53 PF07767.11 KEG08436.1 - 6.2 6.1 17.1 0.42 10.0 11.7 1.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KEG08436.1 - 8.9 4.5 11.0 15 3.7 11.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Roc PF08477.13 KEG08437.1 - 5.8e-11 42.7 0.0 3.4e-05 24.0 0.0 2.5 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEG08437.1 - 7.8e-10 38.6 0.0 0.00038 20.1 0.0 2.6 3 0 0 3 3 3 2 Ras family Arf PF00025.21 KEG08437.1 - 0.0004 19.9 0.0 0.92 8.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KEG08437.1 - 0.0061 15.8 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit zf_Hakai PF18408.1 KEG08438.1 - 0.063 13.0 0.2 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain WD40 PF00400.32 KEG08439.1 - 2.2e-16 59.9 2.6 4.9e-05 24.0 0.4 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG08439.1 - 0.00014 22.2 1.4 6.4 7.4 0.0 5.2 6 0 0 6 6 6 1 PQQ-like domain Pex14_N PF04695.13 KEG08439.1 - 0.37 11.5 10.8 1.2 9.8 1.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mpp10 PF04006.12 KEG08439.1 - 0.47 8.8 31.4 0.0053 15.3 22.3 2.0 2 0 0 2 2 2 0 Mpp10 protein NOA36 PF06524.12 KEG08439.1 - 0.64 9.3 21.3 0.024 14.0 14.4 2.0 2 0 0 2 2 2 0 NOA36 protein DUF2457 PF10446.9 KEG08439.1 - 0.9 8.6 29.8 0.29 10.3 23.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KEG08439.1 - 2.8 7.2 35.7 0.064 12.6 26.5 2.0 2 0 0 2 2 2 0 BUD22 Sporozoite_P67 PF05642.11 KEG08439.1 - 2.8 5.9 10.1 0.049 11.7 2.4 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CDC27 PF09507.10 KEG08439.1 - 3.2 7.1 34.8 0.036 13.5 23.1 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 KEG08439.1 - 4.1 5.4 32.5 6.9 4.6 32.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 KEG08439.1 - 4.7 6.1 12.3 3.3 6.6 7.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 KEG08439.1 - 7 4.4 9.2 14 3.5 9.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 KEG08439.1 - 7 5.8 7.0 15 4.7 5.8 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter CPSF100_C PF13299.6 KEG08439.1 - 7.3 6.7 17.5 18 5.5 12.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_L29 PF00831.23 KEG08440.1 - 3.6e-16 58.9 4.5 3.6e-16 58.9 4.5 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein DUF1967 PF09269.11 KEG08440.1 - 0.05 13.5 0.8 0.48 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) MRP-L47 PF06984.13 KEG08440.1 - 0.053 13.6 1.0 0.053 13.6 1.0 2.0 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) EcoEI_R_C PF08463.10 KEG08440.1 - 0.27 11.3 6.3 0.15 12.2 1.8 2.0 1 1 1 2 2 2 0 EcoEI R protein C-terminal TBD PF12845.7 KEG08440.1 - 1.5 8.8 5.1 1 9.3 0.2 2.5 3 0 0 3 3 3 0 TBD domain Trypan_PARP PF05887.11 KEG08441.1 - 1.4e-05 25.0 25.1 2.4e-05 24.3 25.1 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 KEG08441.1 - 8.8e-05 22.7 15.9 9.7e-05 22.5 15.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KEG08441.1 - 0.19 10.0 14.3 0.2 9.9 14.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TonB_N PF16031.5 KEG08441.1 - 1.3 9.5 53.7 0.33 11.5 50.3 1.7 1 1 1 2 2 2 0 TonB polyproline region Suf PF05843.14 KEG08441.1 - 6.3 6.7 11.3 9 6.2 11.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Sec1 PF00995.23 KEG08442.1 - 2.2e-78 264.9 0.0 2.6e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CAP_N PF01213.19 KEG08442.1 - 0.61 9.5 1.8 1 8.8 1.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CutC PF03932.14 KEG08444.1 - 6.5e-61 205.4 0.8 7.5e-61 205.1 0.8 1.0 1 0 0 1 1 1 1 CutC family AP_endonuc_2 PF01261.24 KEG08444.1 - 2.3e-05 23.9 0.1 5.7e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Asparaginase_C PF17763.1 KEG08444.1 - 0.068 13.4 1.9 0.28 11.4 0.1 2.4 2 1 1 3 3 3 0 Glutaminase/Asparaginase C-terminal domain ANTH PF07651.16 KEG08445.1 - 1.1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KEG08445.1 - 1e-08 35.3 0.4 1.9e-08 34.4 0.4 1.4 1 0 0 1 1 1 1 ENTH domain VGPC1_C PF16799.5 KEG08446.1 - 0.033 14.2 0.2 0.033 14.2 0.2 3.4 4 1 1 5 5 5 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HisKA PF00512.25 KEG08446.1 - 0.043 13.8 14.1 0.27 11.3 0.0 4.9 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF3437 PF11919.8 KEG08446.1 - 0.074 13.0 0.0 28 4.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) BCDHK_Adom3 PF10436.9 KEG08447.1 - 7.2e-29 100.7 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEG08447.1 - 5.8e-05 23.6 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEG08447.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2046 PF09755.9 KEG08449.1 - 2.8e-05 23.5 30.0 3.2e-05 23.3 23.3 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) HOOK PF05622.12 KEG08449.1 - 0.026 12.7 32.0 0.27 9.4 24.8 2.2 2 0 0 2 2 2 0 HOOK protein DUF4407 PF14362.6 KEG08449.1 - 0.046 13.1 23.8 0.41 10.0 7.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KEG08449.1 - 0.53 9.8 23.3 0.47 10.0 14.6 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Macoilin PF09726.9 KEG08449.1 - 0.67 8.4 34.0 0.073 11.6 25.7 2.6 2 1 0 2 2 2 0 Macoilin family MAP7 PF05672.11 KEG08449.1 - 3.2 7.4 42.3 2.9 7.6 4.7 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Leucyl-specific PF14795.6 KEG08449.1 - 7.9 6.6 7.1 19 5.4 0.2 3.1 2 1 0 2 2 2 0 Leucine-tRNA synthetase-specific domain GDA1_CD39 PF01150.17 KEG08450.1 - 7.7e-72 242.3 0.0 1.1e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KEG08450.1 - 0.00017 21.1 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 Ppx/GppA phosphatase family HK_sensor PF16750.5 KEG08450.1 - 0.012 15.8 0.6 0.031 14.6 0.6 1.7 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase LRR_8 PF13855.6 KEG08451.1 - 5.5e-16 58.1 22.8 3.6e-08 33.0 7.2 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KEG08451.1 - 5.5e-11 42.5 13.2 1.1e-05 25.7 2.2 3.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG08451.1 - 7.9e-05 22.7 11.9 9.3 7.2 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 KEG08451.1 - 0.11 12.0 1.3 0.28 10.7 0.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeat NPV_P10 PF05531.12 KEG08452.1 - 0.00074 19.9 0.1 0.00074 19.9 0.1 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF445 PF04286.12 KEG08452.1 - 0.027 14.3 3.2 0.033 14.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Hypoth_Ymh PF09509.10 KEG08452.1 - 0.25 11.2 4.7 0.56 10.1 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Coat_F PF07875.12 KEG08452.1 - 0.72 10.1 4.2 0.27 11.5 0.6 2.1 2 0 0 2 2 2 0 Coat F domain GTSE1_N PF15259.6 KEG08452.1 - 2.5 8.3 7.1 9.6 6.4 7.1 1.9 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 DUF4407 PF14362.6 KEG08452.1 - 2.8 7.2 12.1 3.6 6.9 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 KEG08452.1 - 3 6.2 10.6 3.9 5.8 10.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein MFS_1 PF07690.16 KEG08453.1 - 5.3e-17 61.8 20.7 4.8e-15 55.3 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CHS5_N PF16892.5 KEG08453.1 - 0.033 14.1 0.1 0.081 12.9 0.1 1.7 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus EF-hand_6 PF13405.6 KEG08455.1 - 0.00091 19.0 0.2 0.0035 17.2 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KEG08455.1 - 0.0016 17.8 0.3 0.0038 16.7 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KEG08455.1 - 0.0024 17.3 0.8 0.0064 15.9 0.8 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KEG08455.1 - 0.0026 17.6 0.6 0.0095 15.8 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KEG08455.1 - 0.012 16.1 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 KEG08455.1 - 5.9 7.9 9.4 24 6.0 0.2 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Dynein_light PF01221.18 KEG08456.1 - 2.2e-19 69.5 0.2 8.4e-19 67.7 0.2 1.7 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 KEG08456.1 - 1.4e-07 32.0 0.0 2.5e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Ground-like domain Tombus_movement PF05318.12 KEG08456.1 - 0.11 13.3 0.0 0.18 12.7 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus movement protein Utp21 PF04192.12 KEG08457.1 - 3.6e-24 85.6 0.0 6.1e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KEG08457.1 - 2e-12 47.4 2.9 0.0099 16.7 0.0 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG08457.1 - 4e-10 39.8 0.0 4.3e-06 26.9 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEG08457.1 - 8.8e-08 32.0 0.4 3.1e-06 26.9 0.1 2.5 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KEG08457.1 - 0.014 14.1 0.1 0.086 11.5 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Utp12 PF04003.12 KEG08457.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family SpoIIIAH PF12685.7 KEG08457.1 - 0.34 10.7 1.7 0.56 10.0 1.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 KEG08457.1 - 1.6 6.9 4.3 4.4 5.5 0.0 2.4 2 0 0 2 2 2 0 CDC45-like protein PCRF PF03462.18 KEG08458.1 - 0.018 14.9 0.1 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 PCRF domain LPD5 PF18799.1 KEG08458.1 - 0.14 12.6 1.4 0.45 10.9 0.2 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 DUF1054 PF06335.12 KEG08459.1 - 0.28 11.1 1.4 0.51 10.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) DUF1376 PF07120.11 KEG08460.1 - 0.052 13.9 0.2 1.9 8.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1376) UDPGP PF01704.18 KEG08462.1 - 9.9e-12 44.2 0.0 1.4e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase XRN_N PF03159.18 KEG08463.1 - 7.2e-70 235.2 0.0 1.6e-69 234.0 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KEG08463.1 - 1.2e-40 139.9 0.0 1.6e-26 93.2 0.0 2.3 1 1 1 2 2 2 2 Xrn1 helical domain zf-RanBP PF00641.18 KEG08463.1 - 0.015 14.6 3.3 0.031 13.6 3.3 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PRKG1_interact PF15898.5 KEG08465.1 - 0.15 12.9 3.7 0.2 12.6 0.4 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMEM171 PF15471.6 KEG08465.1 - 0.77 8.7 2.3 1.4 7.8 2.3 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 SlyX PF04102.12 KEG08465.1 - 4.3 8.0 10.0 15 6.3 0.2 3.6 2 1 1 3 3 3 0 SlyX DnaJ PF00226.31 KEG08466.1 - 1.9e-11 43.9 1.3 3.4e-11 43.1 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain NARP1 PF12569.8 KEG08467.1 - 5.5e-84 282.9 18.9 1.5e-79 268.2 12.1 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KEG08467.1 - 9.2e-11 41.1 10.1 3.4e-05 23.5 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG08467.1 - 4.9e-08 32.5 22.1 0.0081 16.2 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG08467.1 - 3.2e-05 24.5 10.9 4.9 7.9 0.0 7.1 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG08467.1 - 4.9e-05 23.7 15.7 7.6 7.1 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG08467.1 - 5.2e-05 23.0 1.4 0.31 11.2 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG08467.1 - 6.4e-05 22.5 1.2 0.93 9.2 0.2 3.9 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.6 KEG08467.1 - 0.00018 21.6 3.1 0.017 15.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG08467.1 - 0.00029 20.8 0.5 0.86 9.7 0.1 3.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KEG08467.1 - 0.00091 19.9 22.6 0.0015 19.1 0.0 7.8 5 3 4 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG08467.1 - 0.0087 16.3 17.8 0.12 12.6 0.0 6.3 4 2 1 6 6 6 2 Tetratricopeptide repeat Sec10 PF07393.11 KEG08467.1 - 0.0095 14.4 0.1 0.2 10.0 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec10 ANAPC3 PF12895.7 KEG08467.1 - 0.013 15.7 13.7 0.14 12.4 0.2 4.7 3 2 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KEG08467.1 - 0.042 14.1 19.8 1.5 9.3 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG08467.1 - 0.093 13.2 6.4 3.1 8.4 0.0 5.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG08467.1 - 7.2 7.5 0.0 7.2 7.5 0.0 5.1 7 0 0 7 7 3 0 Tetratricopeptide repeat DUF778 PF05608.12 KEG08468.1 - 1.1e-32 113.9 0.8 7.2e-21 75.4 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Peptidase_C97 PF05903.14 KEG08468.1 - 0.0059 16.4 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 KEG08468.1 - 0.0071 16.0 0.1 0.032 13.8 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4796) LRAT PF04970.13 KEG08468.1 - 0.17 12.2 0.1 0.23 11.7 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase ADK PF00406.22 KEG08469.1 - 9.2e-40 136.2 0.0 1.4e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEG08469.1 - 8.3e-22 78.1 1.0 7.1e-21 75.1 1.0 2.0 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 KEG08469.1 - 0.00098 19.5 0.1 0.26 11.6 0.0 2.4 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA PF00004.29 KEG08469.1 - 0.0019 18.6 0.0 0.0058 17.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEG08469.1 - 0.0031 18.1 0.1 0.0096 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG08469.1 - 0.12 12.5 0.0 0.45 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DnaJ PF00226.31 KEG08470.1 - 1.1e-19 70.2 0.8 2e-19 69.4 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.20 KEG08471.1 - 1.1e-50 166.5 148.2 0.00029 20.6 3.5 26.8 27 0 0 27 27 27 20 MORN repeat FYVE PF01363.21 KEG08471.1 - 6.1e-24 84.0 24.0 1.1e-17 63.9 12.7 2.4 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 KEG08471.1 - 0.0034 17.6 15.0 0.094 12.9 6.0 2.4 2 0 0 2 2 2 2 FYVE-type zinc finger MelC1 PF06236.11 KEG08471.1 - 0.05 13.7 0.0 0.31 11.1 0.0 2.4 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF3048_C PF17479.2 KEG08471.1 - 0.76 10.2 11.7 2.1 8.8 0.3 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain Cyt-b5 PF00173.28 KEG08472.1 - 9.3e-20 70.6 0.0 1.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Androgen_recep PF02166.16 KEG08472.1 - 0.021 13.7 1.9 0.04 12.8 1.9 1.5 1 0 0 1 1 1 0 Androgen receptor DUF3984 PF13136.6 KEG08472.1 - 0.074 12.4 3.7 0.098 12.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SelP_N PF04592.14 KEG08472.1 - 2.7 7.3 12.0 4.7 6.5 12.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CTP_transf_like PF01467.26 KEG08473.1 - 2.5e-07 31.0 0.1 9.1e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KEG08473.1 - 0.052 13.4 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase EF-hand_1 PF00036.32 KEG08473.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 EF hand ABC_tran PF00005.27 KEG08474.1 - 2e-20 73.7 0.0 5.4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG08474.1 - 1.4e-06 28.3 0.2 0.057 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEG08474.1 - 1.8e-05 24.7 0.3 0.00042 20.3 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KEG08474.1 - 0.00038 20.0 0.2 0.0062 16.0 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG08474.1 - 0.00081 19.1 0.1 0.0033 17.1 0.1 2.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_membrane PF00664.23 KEG08474.1 - 0.0009 19.0 7.9 0.0021 17.7 7.9 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.6 KEG08474.1 - 0.0052 17.1 0.4 0.017 15.4 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG08474.1 - 0.013 15.8 0.1 0.037 14.4 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KEG08474.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KEG08474.1 - 0.076 12.6 0.2 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEG08474.1 - 0.082 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KEG08474.1 - 0.15 12.3 0.0 0.77 10.0 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Corazonin PF17308.2 KEG08476.1 - 0.015 15.7 6.6 0.27 11.6 3.4 2.5 2 0 0 2 2 2 0 Pro-corazonin Gly_rich PF12810.7 KEG08476.1 - 0.83 9.5 7.7 1.3 8.8 7.7 1.2 1 0 0 1 1 1 0 Glycine rich protein Ras PF00071.22 KEG08477.1 - 2.5e-60 202.7 0.4 2.9e-60 202.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG08477.1 - 7.5e-34 116.5 0.0 1.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG08477.1 - 3.7e-14 52.6 0.1 4.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG08477.1 - 6.8e-06 25.6 0.1 8.5e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG08477.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG08477.1 - 0.00031 20.3 0.3 0.0014 18.3 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEG08477.1 - 0.00043 20.2 0.7 0.14 12.0 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 KEG08477.1 - 0.014 15.2 0.3 0.046 13.5 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KEG08477.1 - 0.022 15.0 0.1 0.054 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 KEG08477.1 - 0.037 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KEG08477.1 - 0.051 14.0 0.0 0.087 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEG08477.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KEG08477.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF89 PF01937.19 KEG08477.1 - 0.11 11.4 0.2 0.14 11.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 SRPRB PF09439.10 KEG08477.1 - 0.12 11.8 0.1 0.33 10.4 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DNA_pol_E_B PF04042.16 KEG08477.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B A_deaminase PF00962.22 KEG08479.1 - 1.1e-93 314.1 0.5 1e-82 278.1 0.0 4.1 4 1 1 5 5 5 3 Adenosine/AMP deaminase TPP_enzyme_M PF00205.22 KEG08480.1 - 0.08 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Glypican PF01153.19 KEG08480.1 - 0.34 9.7 0.8 0.54 9.0 0.1 1.6 2 0 0 2 2 2 0 Glypican DUF2605 PF10792.9 KEG08482.1 - 0.042 13.8 0.1 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) C2 PF00168.30 KEG08484.1 - 2e-23 82.6 0.0 4.6e-16 59.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KEG08484.1 - 5.6e-12 45.5 0.0 9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain TetR_C_34 PF17929.1 KEG08484.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain BBS2_C PF14782.6 KEG08484.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal TRIF-NTD PF17798.1 KEG08485.1 - 0.056 13.5 1.0 0.056 13.5 1.0 2.3 3 0 0 3 3 3 0 TRIF N-terminal domain RRM_1 PF00076.22 KEG08486.1 - 1.3e-13 50.5 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG PF10961.8 KEG08486.1 - 0.65 10.6 7.6 1.3 9.7 7.6 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Hus1 PF04005.12 KEG08487.1 - 3.8e-67 226.4 0.0 5.2e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein CDC45 PF02724.14 KEG08487.1 - 0.4 8.9 3.2 0.6 8.3 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KEG08487.1 - 0.6 8.6 6.6 0.85 8.1 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.8 KEG08487.1 - 1.7 9.7 11.9 2.8 9.0 11.9 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal zf-RING_UBOX PF13445.6 KEG08488.1 - 1.2e-05 25.2 6.3 2.3e-05 24.3 6.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG08488.1 - 7.8e-05 22.5 6.8 0.00014 21.6 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG08488.1 - 0.00011 22.0 8.0 0.00021 21.1 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG08488.1 - 0.00013 21.8 6.9 0.00034 20.5 6.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KEG08488.1 - 0.00066 19.8 8.3 0.0012 19.0 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KEG08488.1 - 0.013 15.3 5.5 0.06 13.2 5.5 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KEG08488.1 - 0.03 14.6 7.6 0.065 13.6 7.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KEG08488.1 - 0.39 10.6 7.1 0.73 9.7 7.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG08488.1 - 0.82 9.6 6.3 1.9 8.4 5.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 AATF-Che1 PF13339.6 KEG08488.1 - 0.87 10.3 4.0 1.1 9.9 0.2 2.9 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor adh_short_C2 PF13561.6 KEG08489.1 - 1.4e-40 139.4 0.6 1.6e-40 139.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEG08489.1 - 1.8e-30 105.8 0.0 2.3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KEG08489.1 - 0.011 15.2 0.1 0.031 13.8 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KEG08489.1 - 0.024 14.6 0.2 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 KR domain ABC_membrane PF00664.23 KEG08490.1 - 4.3e-31 108.6 19.0 8.9e-31 107.5 19.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEG08490.1 - 1.7e-27 96.6 0.0 3.1e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEG08490.1 - 9.2e-05 22.0 0.1 0.021 14.2 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG08490.1 - 0.0036 17.0 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KEG08490.1 - 0.014 15.2 0.1 1.3 8.8 0.2 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TrwB_AAD_bind PF10412.9 KEG08490.1 - 0.033 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KEG08490.1 - 0.044 13.9 0.3 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KEG08490.1 - 0.07 12.5 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KEG08490.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KEG08490.1 - 0.17 12.2 0.1 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KEG08493.1 - 2.8e-15 56.4 20.9 0.013 16.4 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG08493.1 - 0.023 15.2 2.9 6.5 7.4 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain DUF3097 PF11296.8 KEG08493.1 - 0.16 11.2 0.3 0.28 10.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) NMT_C PF02799.15 KEG08494.1 - 5.3e-66 222.1 0.0 8.1e-44 149.6 0.0 2.5 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KEG08494.1 - 7.7e-63 211.1 0.0 1.4e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Clat_adaptor_s PF01217.20 KEG08496.1 - 2.9e-34 118.0 4.3 5.1e-18 65.4 1.4 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain LMWPc PF01451.21 KEG08497.1 - 3.3e-08 34.0 0.2 5.8e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase cwf21 PF08312.12 KEG08498.1 - 0.08 13.1 0.3 0.08 13.1 0.3 2.7 3 0 0 3 3 3 0 cwf21 domain BTAD PF03704.17 KEG08498.1 - 0.23 11.9 16.1 0.32 11.4 8.7 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain OPA3 PF07047.12 KEG08498.1 - 1.4 8.7 7.5 2.6 7.9 7.5 1.5 1 1 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Voltage_CLC PF00654.20 KEG08499.1 - 1.3e-90 304.3 33.0 1e-89 301.3 29.5 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KEG08499.1 - 0.00011 22.6 0.0 0.17 12.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF2407_C PF13373.6 KEG08499.1 - 0.93 9.7 0.0 0.93 9.7 0.0 2.3 3 0 0 3 3 3 0 DUF2407 C-terminal domain DUF2605 PF10792.9 KEG08500.1 - 0.14 12.1 6.6 0.74 9.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) LSM PF01423.22 KEG08501.1 - 3.9e-05 23.2 0.1 0.00092 18.9 0.1 2.1 1 1 0 1 1 1 1 LSM domain Par3_HAL_N_term PF12053.8 KEG08503.1 - 1.4e-05 25.3 0.1 2e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 N-terminal of Par3 and HAL proteins Fels1 PF05666.11 KEG08503.1 - 0.081 12.6 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like DUF2838 PF10998.8 KEG08506.1 - 2.7e-18 66.2 6.2 1.3e-14 54.3 2.7 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF2838) DUF996 PF06195.13 KEG08506.1 - 0.045 14.0 6.7 2.3 8.5 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF3742 PF12553.8 KEG08506.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Cwf_Cwc_15 PF04889.12 KEG08507.1 - 6.6 6.4 12.7 23 4.6 12.7 1.9 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4515 PF14988.6 KEG08512.1 - 0.00091 19.1 7.4 0.00091 19.1 7.4 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) FAM178 PF14816.6 KEG08512.1 - 0.0077 15.2 0.3 0.013 14.5 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function, FAM178 Macoilin PF09726.9 KEG08512.1 - 0.31 9.5 6.6 0.39 9.2 6.6 1.3 1 0 0 1 1 1 0 Macoilin family CheY-binding PF09078.11 KEG08512.1 - 0.37 11.0 4.1 0.16 12.1 0.7 2.1 2 1 0 2 2 2 0 CheY binding FapA PF03961.13 KEG08512.1 - 0.48 9.0 7.9 0.73 8.4 7.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Herpes_UL6 PF01763.16 KEG08512.1 - 0.83 8.1 5.2 1.1 7.7 5.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.19 KEG08512.1 - 0.96 7.3 3.4 1.2 7.0 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps54_N PF10475.9 KEG08512.1 - 1.3 8.2 5.8 1.7 7.8 5.8 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Fez1 PF06818.15 KEG08512.1 - 1.5 9.2 17.2 0.24 11.8 12.7 1.8 2 0 0 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 KEG08512.1 - 2 8.7 21.6 0.3 11.3 15.5 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Leu_zip PF15294.6 KEG08512.1 - 2.1 7.8 15.5 0.26 10.7 10.3 1.9 2 0 0 2 2 2 0 Leucine zipper DUF3450 PF11932.8 KEG08512.1 - 3 7.1 15.3 2 7.6 12.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FmiP_Thoc5 PF09766.9 KEG08512.1 - 5.7 6.1 13.2 15 4.8 13.2 1.6 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Exonuc_VII_L PF02601.15 KEG08513.1 - 0.03 13.9 15.7 0.055 13.0 15.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nup88 PF10168.9 KEG08513.1 - 0.1 10.4 13.7 0.19 9.5 13.7 1.4 1 0 0 1 1 1 0 Nuclear pore component zf-CW PF07496.15 KEG08514.1 - 2.9e-08 33.6 6.9 5.2e-08 32.8 6.9 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger DUF2477 PF10631.9 KEG08514.1 - 0.023 15.4 2.1 0.047 14.4 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) CTP_transf_1 PF01148.20 KEG08516.1 - 1e-36 127.1 14.9 7.8e-36 124.2 8.7 2.4 2 1 0 2 2 2 2 Cytidylyltransferase family CarS-like PF01864.17 KEG08516.1 - 0.023 14.7 1.8 0.03 14.3 0.6 1.8 2 0 0 2 2 2 0 CDP-archaeol synthase TMEM52 PF14979.6 KEG08516.1 - 0.1 12.5 2.9 0.12 12.3 0.5 2.2 3 0 0 3 3 3 0 Transmembrane 52 FixQ PF05545.11 KEG08516.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.9 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ FYVE PF01363.21 KEG08517.1 - 8.2e-14 51.5 18.2 1.4e-13 50.7 18.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger Zn-ribbon_8 PF09723.10 KEG08517.1 - 1 9.6 5.0 5 7.3 5.0 2.2 1 0 0 1 1 1 0 Zinc ribbon domain TPR_2 PF07719.17 KEG08518.1 - 1.9e-13 49.4 16.7 0.086 13.0 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEG08518.1 - 4e-11 43.4 6.1 2.8e-06 27.8 1.5 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG08518.1 - 2.8e-10 39.6 17.7 0.018 14.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat CS PF04969.16 KEG08518.1 - 4.4e-06 27.6 0.0 7.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_19 PF14559.6 KEG08518.1 - 8.8e-06 26.1 7.6 3.1e-05 24.4 0.1 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG08518.1 - 9.6e-05 22.9 17.4 0.00074 20.1 0.6 5.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEG08518.1 - 0.00031 20.5 15.6 0.5 10.3 0.5 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG08518.1 - 0.00079 19.3 10.0 1.1 9.4 0.2 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG08518.1 - 0.00082 19.6 16.5 0.17 12.2 0.1 5.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG08518.1 - 0.0028 17.3 12.9 0.0059 16.3 3.1 3.6 4 0 0 4 4 3 2 TPR repeat ANAPC3 PF12895.7 KEG08518.1 - 0.0074 16.5 8.3 0.19 11.9 0.6 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC_CDC26 PF10471.9 KEG08518.1 - 0.0089 16.8 7.1 0.0089 16.8 7.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 TPR_9 PF13371.6 KEG08518.1 - 0.01 16.0 11.0 0.61 10.3 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG08518.1 - 0.018 15.2 3.0 30 5.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt20 PF12090.8 KEG08518.1 - 0.58 9.7 8.0 0.88 9.1 8.0 1.3 1 0 0 1 1 1 0 Spt20 family TPR_4 PF07721.14 KEG08518.1 - 0.77 10.6 7.0 4.1 8.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydin_ADK PF17213.3 KEG08518.1 - 1.7 8.9 6.3 2.9 8.1 6.3 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TPR_6 PF13174.6 KEG08518.1 - 3.8 8.4 7.9 5.1 7.9 1.2 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat MRP-S27 PF10037.9 KEG08518.1 - 6.5 5.5 13.1 1.9 7.3 9.7 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Prefoldin PF02996.17 KEG08519.1 - 2.6e-08 33.8 3.7 2.4e-07 30.7 0.1 2.4 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin_3 PF13758.6 KEG08519.1 - 6.9e-05 22.8 5.5 0.0036 17.3 0.1 2.4 2 0 0 2 2 2 2 Prefoldin subunit DUF3775 PF12616.8 KEG08520.1 - 0.044 13.8 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Amastin PF07344.11 KEG08521.1 - 5e-39 133.6 6.0 6.5e-39 133.2 6.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KEG08521.1 - 0.097 12.5 9.4 0.17 11.7 9.4 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SARAF PF06682.12 KEG08521.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Amastin PF07344.11 KEG08522.1 - 1.5e-30 106.1 8.6 2e-30 105.7 8.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PDZ_assoc PF10600.9 KEG08522.1 - 0.21 12.5 2.5 0.32 11.9 0.8 2.1 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors Hydrolase_3 PF08282.12 KEG08523.1 - 1.8e-42 145.9 0.0 1.4e-41 142.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEG08523.1 - 3.7e-13 49.6 0.0 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 KEG08523.1 - 5e-06 27.0 0.0 0.077 13.4 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEG08523.1 - 4.9e-05 23.7 0.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KEG08523.1 - 0.00082 18.6 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Glyoxalase PF00903.25 KEG08523.1 - 0.0013 18.9 0.0 2.2 8.5 0.0 2.8 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hydrolase_6 PF13344.6 KEG08523.1 - 0.1 12.7 0.0 0.37 10.9 0.0 2.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase zf-CCCH PF00642.24 KEG08524.1 - 0.00011 22.0 5.8 0.00011 22.0 5.8 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG08524.1 - 0.002 18.1 5.9 0.0041 17.1 5.9 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEG08524.1 - 0.002 17.9 7.0 0.002 17.9 7.0 1.7 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 KEG08524.1 - 0.04 14.6 1.9 0.062 14.0 1.9 1.4 1 0 0 1 1 1 0 Torus domain IMS PF00817.20 KEG08525.1 - 0.0017 18.4 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IF-2B PF01008.17 KEG08526.1 - 7.2e-36 123.8 0.0 9.8e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family zf-RING_2 PF13639.6 KEG08527.1 - 1.1e-10 41.7 10.6 2.1e-10 40.8 10.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEG08527.1 - 4.2e-10 39.8 7.9 9e-10 38.7 7.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEG08527.1 - 1.7e-06 27.6 7.7 3.6e-06 26.6 7.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KEG08527.1 - 3.3e-06 27.1 8.2 4.6e-06 26.6 5.8 2.3 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KEG08527.1 - 1.2e-05 25.1 11.5 2.2e-05 24.3 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG08527.1 - 1.3e-05 24.9 11.1 2.3e-05 24.1 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG08527.1 - 1.7e-05 24.8 7.9 3.3e-05 23.8 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEG08527.1 - 4.3e-05 23.4 8.7 9e-05 22.4 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEG08527.1 - 0.00026 20.8 7.2 0.00046 20.0 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KEG08527.1 - 0.46 10.4 8.8 1.2 9.1 8.8 1.7 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KEG08527.1 - 0.52 10.6 5.4 1.2 9.4 5.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 KEG08527.1 - 0.84 9.3 6.8 2.1 8.0 6.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KEG08527.1 - 3.8 7.7 9.7 8.8 6.5 9.7 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KEG08527.1 - 5 7.4 8.0 19 5.5 8.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain HC2 PF07382.11 KEG08528.1 - 0.00015 21.9 78.6 0.00039 20.6 78.6 1.7 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF2766 PF10964.8 KEG08528.1 - 6.5 6.8 13.8 0.25 11.3 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2766) HC2 PF07382.11 KEG08529.1 - 6.2e-06 26.4 75.7 0.013 15.6 43.3 1.8 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 MapZ_EC1 PF18041.1 KEG08531.1 - 0.011 16.0 2.6 0.021 15.0 2.3 1.8 1 1 0 1 1 1 0 MapZ extracellular domain 1 BLOC1_2 PF10046.9 KEG08531.1 - 0.055 13.8 0.5 0.091 13.1 0.5 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KEG08531.1 - 0.063 13.9 2.3 1 10.0 0.7 2.4 1 1 1 2 2 2 0 SlyX GAS PF13851.6 KEG08531.1 - 0.2 11.0 4.9 0.27 10.5 4.9 1.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1003 PF06210.11 KEG08531.1 - 0.26 11.4 2.6 2.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) AAA_13 PF13166.6 KEG08531.1 - 0.49 9.0 3.4 0.54 8.8 3.4 1.1 1 0 0 1 1 1 0 AAA domain Com_YlbF PF06133.11 KEG08531.1 - 1.1 9.9 6.9 0.13 12.8 3.0 1.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA LapA_dom PF06305.11 KEG08531.1 - 1.8 8.4 4.7 23 4.9 2.8 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4407 PF14362.6 KEG08531.1 - 2.9 7.1 9.2 3.5 6.9 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KEG08531.1 - 3.9 7.3 5.6 5.6 6.8 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4042 PF13251.6 KEG08532.1 - 6.2e-11 42.3 0.5 7e-10 38.9 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 KEG08532.1 - 0.0046 17.3 7.4 0.28 11.6 0.6 4.3 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KEG08532.1 - 0.049 14.2 3.6 16 6.2 0.1 3.8 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 KEG08532.1 - 0.12 12.7 10.4 4.1 7.9 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat Pkinase PF00069.25 KEG08533.1 - 1.9e-06 27.4 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08533.1 - 0.00047 19.5 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KEG08533.1 - 0.0083 16.3 0.4 14 6.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KEG08533.1 - 0.11 12.6 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UvrD_C PF13361.6 KEG08534.1 - 0.018 14.5 1.0 0.018 14.5 1.0 3.0 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Phage_T7_Capsid PF05396.11 KEG08534.1 - 0.072 13.5 0.9 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Phage T7 capsid assembly protein PuR_N PF09182.10 KEG08534.1 - 0.073 13.0 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal V-SNARE_C PF12352.8 KEG08534.1 - 0.13 12.5 3.6 0.45 10.8 0.4 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.12 KEG08534.1 - 0.2 12.2 4.3 5.7 7.5 0.4 3.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RAP1 PF07218.11 KEG08534.1 - 2.3 6.4 8.3 4.4 5.5 4.7 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Dor1 PF04124.12 KEG08534.1 - 2.9 6.5 9.7 1.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Dor1-like family YebO PF13974.6 KEG08534.1 - 3.5 7.8 7.0 0.3 11.2 0.5 2.6 2 0 0 2 2 2 0 YebO-like protein NBP1 PF08537.10 KEG08534.1 - 4.2 6.7 19.0 37 3.6 12.8 3.6 2 1 1 3 3 3 0 Fungal Nap binding protein NBP1 PPR PF01535.20 KEG08536.1 - 3.1e-07 30.2 7.0 0.17 12.2 0.1 6.6 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KEG08536.1 - 3.2e-06 27.1 0.0 0.023 14.8 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KEG08536.1 - 1.2e-05 25.3 2.4 2 8.7 0.0 5.6 5 1 1 6 6 6 1 PPR repeat family TPR_19 PF14559.6 KEG08536.1 - 0.023 15.2 1.9 7.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_long PF17177.4 KEG08536.1 - 0.052 12.9 0.8 0.39 10.1 0.1 2.5 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KEG08536.1 - 0.062 14.2 5.4 63 4.8 0.0 5.6 4 2 3 7 7 7 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.22 KEG08537.1 - 4.2e-23 81.4 0.1 5e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Macoilin PF09726.9 KEG08538.1 - 0.013 14.1 13.9 0.02 13.5 13.9 1.2 1 0 0 1 1 1 0 Macoilin family MutS_III PF05192.18 KEG08538.1 - 0.082 13.1 1.2 0.89 9.7 1.1 2.2 1 1 0 1 1 1 0 MutS domain III DUF3138 PF11336.8 KEG08538.1 - 0.37 9.4 1.3 0.63 8.6 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_M1_N PF17900.1 KEG08541.1 - 8.3e-22 78.3 0.0 1.4e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KEG08541.1 - 1.6e-08 34.4 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain SelP_N PF04592.14 KEG08541.1 - 2.5 7.4 12.8 3.8 6.8 12.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M1 PF01433.20 KEG08542.1 - 8.6e-11 41.8 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KEG08542.1 - 1.9e-05 24.3 0.2 4.1e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Spore_YhcN_YlaJ PF09580.10 KEG08543.1 - 0.00032 20.8 3.8 0.00032 20.8 3.8 2.8 3 0 0 3 3 3 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ERCC4 PF02732.15 KEG08543.1 - 0.011 16.0 2.5 2 8.6 0.2 2.4 2 0 0 2 2 2 0 ERCC4 domain RXT2_N PF08595.11 KEG08543.1 - 0.18 11.8 16.7 0.87 9.6 0.6 3.5 3 0 0 3 3 3 0 RXT2-like, N-terminal Sin_N PF04801.13 KEG08543.1 - 0.42 9.8 17.6 9.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region DUF5600 PF18150.1 KEG08545.1 - 2.8e-17 63.2 0.0 6.9e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 KEG08545.1 - 2.2e-14 53.9 0.0 1.6e-12 47.8 0.0 2.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KEG08545.1 - 3.9e-07 30.1 0.0 9.2e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 KEG08545.1 - 2e-06 27.5 0.3 4.6e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein RsgA_GTPase PF03193.16 KEG08545.1 - 0.0063 16.4 0.2 2.6 7.9 0.0 3.6 4 0 0 4 4 4 1 RsgA GTPase Glucodextran_N PF09137.11 KEG08545.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucodextranase, domain N Androgen_recep PF02166.16 KEG08545.1 - 6.5 5.5 14.8 3.1 6.5 12.6 1.3 1 1 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 KEG08545.1 - 6.9 6.8 10.7 23 5.2 10.3 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 U-box PF04564.15 KEG08547.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KEG08547.1 - 0.00083 19.5 0.0 0.0033 17.5 0.0 2.1 1 1 1 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein GAS PF13851.6 KEG08547.1 - 0.0061 15.9 0.5 0.011 15.1 0.5 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KEG08547.1 - 0.011 14.0 0.1 0.015 13.5 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Val_tRNA-synt_C PF10458.9 KEG08547.1 - 0.018 15.3 0.0 0.041 14.2 0.0 1.6 2 0 0 2 2 1 0 Valyl tRNA synthetase tRNA binding arm Fib_alpha PF08702.10 KEG08547.1 - 0.032 14.4 1.2 0.055 13.7 1.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.9 KEG08547.1 - 0.043 13.8 0.2 0.21 11.6 0.4 2.1 2 1 0 2 2 2 0 Short coiled-coil protein CENP-F_leu_zip PF10473.9 KEG08547.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPACA9 PF15120.6 KEG08547.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF677 PF05055.12 KEG08547.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF948 PF06103.11 KEG08547.1 - 0.15 12.3 0.2 0.35 11.2 0.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2937 PF11157.8 KEG08547.1 - 0.16 11.6 0.7 3.2 7.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) ZapB PF06005.12 KEG08547.1 - 0.22 12.0 0.6 0.46 10.9 0.6 1.6 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KEG08547.1 - 2.6 8.7 5.3 2 9.1 0.1 2.6 2 1 0 2 2 2 0 Initiation control protein YabA DUF1523 PF07509.11 KEG08550.1 - 0.1 11.9 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Peptidase_C1 PF00112.23 KEG08551.1 - 1.3e-59 201.9 2.6 1.6e-59 201.6 2.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KEG08551.1 - 0.0014 18.5 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KEG08551.1 - 0.14 10.9 2.5 0.13 11.0 0.7 1.7 2 0 0 2 2 2 0 Peptidase C1-like family Amidohydro_3 PF07969.11 KEG08552.1 - 7e-08 32.4 0.1 0.021 14.3 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KEG08552.1 - 9.9e-07 28.4 1.1 7.9e-05 22.1 1.1 2.4 1 1 0 1 1 1 1 Amidohydrolase family ADP_PFK_GK PF04587.15 KEG08552.1 - 0.085 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region CDP-OH_P_transf PF01066.21 KEG08555.1 - 4.5e-16 59.4 0.2 4.5e-16 59.4 0.2 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP_transf_like PF01467.26 KEG08555.1 - 4.8e-14 52.7 0.1 1.2e-13 51.5 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KEG08555.1 - 0.32 10.9 1.1 9.9 6.0 0.2 2.9 3 0 0 3 3 3 0 FAD synthetase DUF2079 PF09852.9 KEG08555.1 - 1.5 7.6 14.6 4.6 6.0 8.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) Consortin_C PF15281.6 KEG08555.1 - 1.6 8.7 4.9 0.37 10.8 0.9 2.0 2 0 0 2 2 2 0 Consortin C-terminus zf-CCCH PF00642.24 KEG08556.1 - 6e-05 22.9 7.0 0.0094 15.9 2.5 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG08556.1 - 0.0062 17.2 0.6 0.57 10.9 0.1 2.5 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 KEG08556.1 - 0.091 13.0 3.9 4.5 7.5 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 KEG08556.1 - 0.17 12.0 15.3 1.2 9.2 5.6 3.2 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 KEG08556.1 - 0.94 10.0 9.5 5.1 7.7 2.8 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KEG08557.1 - 1.7e-05 24.7 2.2 0.23 11.6 0.4 3.3 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KEG08557.1 - 0.0035 17.2 11.4 0.22 11.5 4.0 2.8 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KEG08557.1 - 0.07 13.6 11.3 0.092 13.3 0.6 3.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KEG08557.1 - 0.31 11.8 5.7 1.5 9.6 1.7 2.6 2 1 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KEG08557.1 - 4.6 7.5 8.8 10 6.4 3.0 2.7 2 1 0 2 2 2 0 Zinc-finger containing family HMG-CoA_red PF00368.18 KEG08559.1 - 5.4e-138 460.0 0.7 6.2e-138 459.8 0.7 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.19 KEG08560.1 - 3.6e-34 117.4 2.1 4.2e-34 117.2 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Hormone_2 PF00123.20 KEG08560.1 - 0.14 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptide hormone FKBP_C PF00254.28 KEG08561.1 - 0.018 15.4 0.0 0.052 13.9 0.0 1.8 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase ETC_C1_NDUFA4 PF04800.12 KEG08561.1 - 0.083 13.2 0.1 0.41 10.9 0.1 2.1 2 0 0 2 2 2 0 ETC complex I subunit conserved region CRS1_YhbY PF01985.21 KEG08562.1 - 0.068 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Peptidase_M8 PF01457.16 KEG08565.1 - 5.3e-140 467.6 0.0 6.7e-140 467.3 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.6 KEG08565.1 - 0.049 13.8 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Glyco_transf_64 PF09258.10 KEG08566.1 - 4e-14 52.5 0.0 9.8e-13 47.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain tRNA_bind PF01588.20 KEG08567.1 - 3.5e-25 87.9 0.0 5.2e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Polyketide_cyc PF03364.20 KEG08569.1 - 5.2e-14 52.6 0.2 9.5e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport E1-E2_ATPase PF00122.20 KEG08570.1 - 4.2e-45 153.5 2.3 4.2e-45 153.5 2.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEG08570.1 - 4.1e-29 101.6 4.0 4.1e-29 101.6 4.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KEG08570.1 - 5.5e-16 58.4 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEG08570.1 - 5.7e-13 49.6 0.0 4.6e-12 46.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEG08570.1 - 3e-06 26.8 0.0 7.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEG08570.1 - 3.8e-05 23.5 0.5 6.5e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.23 KEG08571.1 - 1.2e-71 241.4 0.0 1.5e-69 234.5 0.0 3.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08571.1 - 1.6e-20 73.5 0.0 4.6e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 KEG08571.1 - 1.2 8.2 5.2 18 4.3 1.7 2.8 2 1 1 3 3 3 0 PIF1-like helicase ArfGap PF01412.18 KEG08573.1 - 4.5e-29 100.9 0.7 8.2e-29 100.1 0.7 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2917 PF11142.8 KEG08575.1 - 0.031 13.7 0.0 4.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) TruB_C_2 PF16198.5 KEG08576.1 - 0.091 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DAGK_acc PF00609.19 KEG08577.1 - 2.6e-28 99.4 0.0 7.3e-27 94.7 0.0 2.7 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KEG08577.1 - 2.3e-08 33.7 0.1 1.4e-07 31.1 0.1 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adhesin_E PF16747.5 KEG08578.1 - 0.067 13.2 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Surface-adhesin protein E BatA PF07584.11 KEG08578.1 - 0.11 12.9 0.0 0.75 10.2 0.0 2.0 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4821 PF16092.5 KEG08579.1 - 3.4e-19 69.5 0.0 5.8e-17 62.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 KEG08579.1 - 2.1e-08 33.8 0.0 4.6e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 KEG08580.1 - 7.3e-52 173.7 0.0 5.7e-27 93.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KEG08580.1 - 9.6e-15 55.0 0.0 1.8e-06 28.4 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain ERp29 PF07749.12 KEG08580.1 - 3.8e-12 47.0 0.0 6.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KEG08580.1 - 1.9e-10 40.6 0.0 0.0001 21.8 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KEG08580.1 - 2.1e-10 40.6 0.0 0.00074 19.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KEG08580.1 - 2.2e-08 34.3 0.0 0.012 15.9 0.0 4.2 2 2 2 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.21 KEG08580.1 - 1.9e-06 27.8 0.0 0.072 13.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 KEG08580.1 - 3.8e-06 26.7 0.0 0.0049 16.6 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 KEG08580.1 - 1.1e-05 25.2 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29_N PF07912.13 KEG08580.1 - 1.2e-05 25.4 0.0 0.019 15.1 0.1 2.4 2 1 0 2 2 2 2 ERp29, N-terminal domain TraF PF13728.6 KEG08580.1 - 7.3e-05 22.7 0.0 0.0069 16.2 0.0 2.7 3 0 0 3 3 3 1 F plasmid transfer operon protein HyaE PF07449.11 KEG08580.1 - 8e-05 22.6 0.0 0.68 9.9 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KEG08580.1 - 0.00064 19.9 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_6 PF13848.6 KEG08580.1 - 0.015 15.2 0.0 0.079 12.9 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_5 PF13743.6 KEG08580.1 - 0.038 13.7 0.1 18 4.9 0.1 3.6 3 1 1 4 4 4 0 Thioredoxin DUF520 PF04461.13 KEG08580.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Thioredoxin_4 PF13462.6 KEG08580.1 - 0.17 12.0 0.0 30 4.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Thioredoxin PF00085.20 KEG08581.1 - 1.6e-22 79.4 0.0 1.9e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KEG08581.1 - 1.1e-07 31.5 0.1 3.4e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KEG08581.1 - 7.2e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KEG08581.1 - 0.00012 22.1 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KEG08581.1 - 0.0002 21.8 0.0 0.00032 21.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEG08581.1 - 0.0053 17.1 0.0 0.29 11.5 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KEG08581.1 - 0.039 13.9 0.0 0.083 12.8 0.0 1.6 2 0 0 2 2 2 0 AhpC/TSA family Redoxin PF08534.10 KEG08581.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin T7SS_ESX1_EccB PF05108.13 KEG08581.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B ERp29_N PF07912.13 KEG08581.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 ERp29, N-terminal domain DUF2012 PF09430.10 KEG08582.1 - 3.2e-32 111.2 0.0 4.9e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 KEG08582.1 - 0.0012 19.0 0.5 0.003 17.8 0.5 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KEG08582.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain SNARE PF05739.19 KEG08583.1 - 7.3e-10 38.7 3.6 8.1e-10 38.5 1.4 1.9 2 0 0 2 2 2 1 SNARE domain DUF2524 PF10732.9 KEG08583.1 - 0.031 14.6 0.0 0.037 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) BLOC1_2 PF10046.9 KEG08584.1 - 0.00074 19.8 2.8 0.0011 19.2 2.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF935 PF06074.12 KEG08584.1 - 0.014 14.2 9.0 0.017 13.9 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Synaptobrevin PF00957.21 KEG08584.1 - 0.56 10.0 3.4 0.78 9.6 3.2 1.5 1 1 0 1 1 1 0 Synaptobrevin Spc7 PF08317.11 KEG08584.1 - 0.67 8.8 13.4 0.75 8.6 13.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein VPS11_C PF12451.8 KEG08584.1 - 0.83 9.9 6.3 0.25 11.6 2.7 2.2 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF3584 PF12128.8 KEG08584.1 - 3.5 5.0 18.0 4 4.8 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 KEG08584.1 - 4.9 7.2 13.2 6.1 6.9 13.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 KEG08584.1 - 6.1 6.3 12.8 6.7 6.2 12.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4051 PF13260.6 KEG08584.1 - 8 6.3 11.0 0.76 9.5 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4051) GvpL_GvpF PF06386.11 KEG08584.1 - 9.5 6.1 13.4 13 5.7 13.4 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ribosomal_60s PF00428.19 KEG08586.1 - 0.011 16.2 0.7 0.021 15.4 0.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3682 PF12446.8 KEG08586.1 - 0.012 16.0 2.5 0.018 15.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Pkinase PF00069.25 KEG08588.1 - 1.1e-41 142.9 0.0 1.5e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08588.1 - 4e-16 59.1 0.0 5.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG08588.1 - 0.0014 18.6 0.4 0.66 9.8 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF4801 PF16059.5 KEG08588.1 - 0.07 13.1 0.3 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4801) DUF2753 PF10952.8 KEG08589.1 - 0.048 13.8 0.3 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) AAA PF00004.29 KEG08590.1 - 1e-30 106.9 0.0 1.6e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG08590.1 - 3.5e-07 30.6 0.7 2.6e-05 24.5 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG08590.1 - 2e-05 25.0 0.1 6.6e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KEG08590.1 - 2.4e-05 24.9 0.0 5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEG08590.1 - 4.9e-05 23.0 0.8 0.0072 15.9 0.8 2.3 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KEG08590.1 - 0.00064 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KEG08590.1 - 0.0011 18.9 0.1 0.0027 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEG08590.1 - 0.0014 18.8 0.0 0.0048 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEG08590.1 - 0.0028 18.0 0.0 0.0078 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 KEG08590.1 - 0.0035 17.2 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEG08590.1 - 0.0052 16.5 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KEG08590.1 - 0.0067 16.2 0.1 0.012 15.4 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase Sigma54_activ_2 PF14532.6 KEG08590.1 - 0.0078 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 KEG08590.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KEG08590.1 - 0.0099 15.8 0.1 0.02 14.8 0.1 1.7 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 KEG08590.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEG08590.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEG08590.1 - 0.021 15.1 0.2 0.056 13.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEG08590.1 - 0.025 13.7 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KEG08590.1 - 0.031 14.0 0.0 0.088 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEG08590.1 - 0.037 14.4 0.4 0.29 11.5 0.2 2.5 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KEG08590.1 - 0.045 14.3 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KEG08590.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KEG08590.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KEG08590.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 KEG08590.1 - 0.12 12.2 0.1 0.36 10.7 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEG08590.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KEG08590.1 - 0.18 11.5 0.3 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Topoisom_bac PF01131.20 KEG08591.1 - 7.8e-106 354.5 0.0 9.7e-106 354.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KEG08591.1 - 2.2e-15 56.7 0.0 4.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Ssu72 PF04722.13 KEG08591.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Ssu72-like protein IMS_C PF11799.8 KEG08591.1 - 0.18 12.5 0.0 0.51 11.1 0.0 1.7 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Erv26 PF04148.13 KEG08593.1 - 3.7e-23 82.5 7.1 5.3e-23 81.9 7.1 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Aminotran_4 PF01063.19 KEG08594.1 - 1.4e-34 119.9 0.0 2.7e-34 119.0 0.0 1.4 2 0 0 2 2 2 1 Amino-transferase class IV Mito_carr PF00153.27 KEG08595.1 - 3.9e-29 100.4 6.0 7e-15 54.7 0.3 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.23 KEG08596.1 - 0.0011 18.7 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin family RE_LlaJI PF09563.10 KEG08596.1 - 0.027 13.7 0.2 0.035 13.3 0.2 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease Rad60-SLD PF11976.8 KEG08596.1 - 0.052 13.4 0.0 0.19 11.5 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2845 PF11006.8 KEG08596.1 - 0.17 12.0 1.4 0.45 10.7 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) GMP_PDE_delta PF05351.11 KEG08597.1 - 3.3e-61 206.0 0.7 3.9e-61 205.7 0.7 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit LCE6A PF15858.5 KEG08598.1 - 0.12 13.1 3.3 0.12 13.1 2.1 1.6 1 1 0 1 1 1 0 Late cornified envelope protein 6A family Pterin_4a PF01329.19 KEG08600.1 - 7.2e-09 35.7 0.0 3.5e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase HrpB_C PF08482.10 KEG08600.1 - 0.097 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal COPI_assoc PF08507.10 KEG08601.1 - 1.8e-08 34.5 4.8 2.4e-08 34.1 4.8 1.2 1 0 0 1 1 1 1 COPI associated protein Vps55 PF04133.14 KEG08601.1 - 0.34 10.9 3.8 11 6.0 0.6 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 55 TNV_CP PF03898.13 KEG08603.1 - 0.013 14.7 0.1 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Satellite tobacco necrosis virus coat protein IHO1 PF15771.5 KEG08603.1 - 0.2 10.4 0.9 0.23 10.2 0.9 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Gti1_Pac2 PF09729.9 KEG08605.1 - 0.047 13.8 2.4 0.066 13.3 2.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Lin-8 PF03353.15 KEG08605.1 - 0.43 10.1 8.1 0.47 10.0 8.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist OAD_gamma PF04277.13 KEG08605.1 - 1 10.0 6.0 0.42 11.2 0.5 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.17 KEG08605.1 - 1.7 7.3 8.5 2 7.1 8.5 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 KEG08605.1 - 1.9 8.4 20.0 2.1 8.2 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KEG08605.1 - 8.6 4.9 8.0 9.7 4.7 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup dCMP_cyt_deam_1 PF00383.23 KEG08606.1 - 1.2e-12 47.6 1.9 3.4e-11 42.9 1.9 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEG08606.1 - 1.5e-12 47.4 0.2 1.7e-11 44.0 0.2 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KEG08606.1 - 0.82 9.7 8.7 0.26 11.4 3.3 2.6 1 1 1 2 2 2 0 Bd3614-like deaminase YqjK PF13997.6 KEG08608.1 - 0.058 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 YqjK-like protein His_Phos_1 PF00300.22 KEG08610.1 - 1.1e-31 110.1 0.0 4e-22 78.9 0.0 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 KEG08611.1 - 6.9e-16 58.5 0.0 1.2e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2584 PF10763.9 KEG08611.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) zf-HIT PF04438.16 KEG08612.1 - 3.9e-07 29.8 11.4 6.3e-07 29.2 11.4 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KEG08612.1 - 0.017 15.2 12.6 0.034 14.3 12.6 1.5 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 KEG08612.1 - 1.7 8.8 9.5 3.3 7.9 9.5 1.5 1 0 0 1 1 1 0 B-box zinc finger TALPID3 PF15324.6 KEG08614.1 - 0.1 10.3 9.3 0.13 9.9 9.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DnaJ PF00226.31 KEG08615.1 - 6.6e-15 55.0 0.2 1.7e-14 53.6 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain FUSC PF04632.12 KEG08615.1 - 0.48 8.9 9.8 0.56 8.7 9.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SurA_N_2 PF13623.6 KEG08615.1 - 0.54 10.1 4.9 0.88 9.4 4.9 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Exonuc_VII_L PF02601.15 KEG08615.1 - 0.79 9.2 10.6 0.98 8.9 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TraV PF09676.10 KEG08615.1 - 0.86 10.6 6.9 19 6.3 6.9 2.3 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) IZUMO PF15005.6 KEG08615.1 - 4.3 7.8 8.0 8.2 6.9 7.8 1.5 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated MCM PF00493.23 KEG08616.1 - 5.8e-84 280.7 0.0 9e-84 280.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEG08616.1 - 2.6e-26 91.9 0.0 4.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEG08616.1 - 1.6e-16 60.5 0.1 3.7e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEG08616.1 - 1.2e-09 38.6 0.0 7.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEG08616.1 - 8e-09 35.2 0.1 1.9e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEG08616.1 - 4.1e-05 23.4 0.0 0.00029 20.6 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KEG08616.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEG08616.1 - 0.005 16.8 0.0 0.017 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) GATase1_like PF07090.11 KEG08616.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative glutamine amidotransferase Complex1_LYR PF05347.15 KEG08617.1 - 3.3e-08 33.4 0.4 5.9e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEG08617.1 - 0.00031 21.4 0.6 0.00043 21.0 0.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ketoacyl-synt PF00109.26 KEG08618.1 - 8.1e-09 35.4 0.1 2.2e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEG08619.1 - 2.4e-28 98.5 0.1 3.1e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KEG08619.1 - 8.6e-06 25.5 0.3 1.4e-05 24.8 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MCR PF18509.1 KEG08619.1 - 0.021 14.4 0.2 0.052 13.1 0.2 1.7 1 0 0 1 1 1 0 Magnetochrome domain RRM_1 PF00076.22 KEG08620.1 - 6.9e-19 67.4 0.0 1.1e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 KEG08621.1 - 0.022 14.4 4.8 0.025 14.2 4.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF2572 PF10833.8 KEG08621.1 - 0.072 12.9 0.0 0.081 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF3464 PF11947.8 KEG08621.1 - 0.1 12.3 1.9 0.12 12.1 1.9 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pro_isomerase PF00160.21 KEG08622.1 - 6.2e-30 104.6 0.0 1.1e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RSN1_7TM PF02714.15 KEG08623.1 - 1e-27 97.1 7.5 1e-27 97.1 7.5 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEG08623.1 - 0.65 9.8 6.0 0.12 12.1 0.2 2.8 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport DUF5473 PF17567.2 KEG08623.1 - 6.1 7.2 7.5 39 4.6 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5473) Adap_comp_sub PF00928.21 KEG08624.1 - 7e-15 55.1 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEG08624.1 - 3e-07 30.5 0.2 5e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FPP PF05911.11 KEG08625.1 - 0.00096 17.5 9.4 0.00096 17.5 9.4 5.6 3 1 1 5 5 5 5 Filament-like plant protein, long coiled-coil ABC_tran_CTD PF16326.5 KEG08626.1 - 0.0016 18.6 14.2 0.024 14.9 0.6 4.5 5 0 0 5 5 5 2 ABC transporter C-terminal domain HALZ PF02183.18 KEG08626.1 - 0.049 13.9 14.3 0.44 10.8 0.3 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.15 KEG08626.1 - 0.088 12.6 21.0 0.48 10.2 0.9 4.9 4 1 1 5 5 5 0 Septum formation initiator Chibby PF14645.6 KEG08626.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.3 2 1 0 2 2 2 0 Chibby family GAS PF13851.6 KEG08626.1 - 0.85 8.9 22.1 0.051 12.9 8.1 3.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KEG08626.1 - 2.4 8.6 28.0 0.74 10.3 3.0 5.2 3 1 2 5 5 5 0 Cell division protein ZapB KELK PF15796.5 KEG08626.1 - 3.5 8.2 17.7 2.4 8.6 0.3 3.8 3 1 0 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KASH_CCD PF14662.6 KEG08626.1 - 3.7 7.3 23.7 0.79 9.5 14.6 3.6 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 KEG08626.1 - 4.6 5.0 6.8 2.1 6.2 3.5 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KEG08626.1 - 4.6 7.3 19.3 2.9 8.0 9.8 3.4 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Hrs_helical PF12210.8 KEG08626.1 - 5.1 7.7 13.5 6.2 7.4 2.2 4.3 4 1 0 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate bZIP_1 PF00170.21 KEG08626.1 - 5.5 7.2 20.6 0.57 10.3 3.0 4.5 4 1 1 5 5 5 0 bZIP transcription factor BRE1 PF08647.11 KEG08626.1 - 6.9 6.8 12.3 0.48 10.5 0.7 3.7 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 KEG08626.1 - 8.8 6.5 20.1 0.73 10.0 8.3 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) C2 PF00168.30 KEG08627.1 - 0.00025 21.3 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain HTH_15 PF12324.8 KEG08627.1 - 0.00067 19.6 0.2 0.0064 16.4 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of alkylmercury lyase DUF4809 PF16067.5 KEG08627.1 - 0.13 12.5 0.6 0.54 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4809) NPBW PF15180.6 KEG08627.1 - 0.14 12.0 0.1 5.9 6.8 0.0 2.9 2 0 0 2 2 2 0 Neuropeptides B and W DUF4407 PF14362.6 KEG08627.1 - 0.84 8.9 27.0 0.012 15.0 10.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPD52 PF04201.15 KEG08627.1 - 1.7 8.3 8.8 1.9 8.1 1.3 3.4 2 1 1 3 3 3 0 Tumour protein D52 family FliD_C PF07195.12 KEG08627.1 - 8.5 5.7 10.2 4.9 6.5 2.1 3.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF4770 PF15994.5 KEG08628.1 - 0.55 10.4 6.7 0.99 9.6 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DnaJ PF00226.31 KEG08629.1 - 1.1e-13 51.1 0.0 2.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 KEG08629.1 - 0.0011 18.8 6.1 0.0018 18.1 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 KEG08629.1 - 0.0024 17.9 15.2 0.0032 17.5 15.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 KEG08629.1 - 0.018 15.0 6.2 0.031 14.2 6.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPP1 PF10341.9 KEG08629.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD zf-C3HC4_2 PF13923.6 KEG08629.1 - 0.93 9.4 6.8 1.7 8.5 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG08629.1 - 2.1 8.7 6.2 3.8 7.9 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain RNB PF00773.19 KEG08632.1 - 1.7e-95 320.1 0.5 3.6e-95 319.1 0.5 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KEG08632.1 - 1.3e-21 76.4 0.0 3.7e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KEG08632.1 - 2.3e-07 30.9 0.3 5.4e-06 26.5 0.1 2.9 3 1 0 3 3 3 1 Cold shock domain Rrp44_CSD1 PF17216.3 KEG08632.1 - 6.7e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 KEG08632.1 - 5.4e-06 26.7 0.2 1.3e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 KEG08632.1 - 0.013 15.5 0.0 0.044 13.8 0.0 1.8 1 1 0 1 1 1 0 S1 domain DED PF01335.21 KEG08633.1 - 0.0088 16.3 0.0 0.092 13.1 0.0 2.8 3 0 0 3 3 3 1 Death effector domain HEAT_UF PF18817.1 KEG08633.1 - 0.032 14.5 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 Endonuclease_NS PF01223.23 KEG08634.1 - 1.2e-60 205.2 0.0 1.5e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 KEG08634.1 - 0.017 15.2 1.6 0.017 15.2 1.6 2.0 2 1 0 2 2 2 0 DNA/RNA non-specific endonuclease ABC1 PF03109.16 KEG08635.1 - 5.6e-23 81.4 0.0 1.2e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KEG08635.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CAF1A PF12253.8 KEG08637.1 - 1.8e-08 34.4 2.3 1.8e-08 34.4 2.3 4.8 4 1 1 5 5 5 1 Chromatin assembly factor 1 subunit A SUIM_assoc PF16619.5 KEG08637.1 - 0.82 9.8 26.8 0.28 11.3 6.2 4.5 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG08637.1 - 3.9 7.0 20.4 2.2 7.9 9.9 3.2 3 0 0 3 3 3 0 Spt20 family ADH_zinc_N_2 PF13602.6 KEG08638.1 - 6.1e-16 59.7 0.1 1.3e-15 58.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEG08638.1 - 1.2e-15 57.7 0.6 2.1e-15 56.9 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEG08638.1 - 8e-05 22.5 0.0 0.00036 20.4 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_PD PF04336.12 KEG08639.1 - 0.15 12.5 2.3 3.3 8.2 0.6 3.5 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase CheY-binding PF09078.11 KEG08639.1 - 0.18 12.0 1.4 7.6 6.7 0.0 2.9 2 0 0 2 2 2 0 CheY binding Spore_III_AB PF09548.10 KEG08639.1 - 0.42 10.7 15.3 0.56 10.3 1.0 2.9 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) ATG_C PF09333.11 KEG08639.1 - 0.43 10.9 5.9 1.1 9.7 0.3 3.7 4 1 0 4 4 3 0 Autophagy-related protein C terminal domain FapA PF03961.13 KEG08639.1 - 0.48 9.0 16.0 0.05 12.2 2.8 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A PSK_trans_fac PF07704.11 KEG08639.1 - 0.55 11.0 8.0 1.8 9.4 0.4 3.6 2 2 0 2 2 2 0 Rv0623-like transcription factor Ribosomal_60s PF00428.19 KEG08639.1 - 1.7 9.2 18.5 0.17 12.5 9.2 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein LMBR1 PF04791.16 KEG08639.1 - 2.4 7.0 8.6 4.7 6.0 8.6 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4404 PF14357.6 KEG08639.1 - 5.3 7.7 17.0 4.8 7.9 4.5 4.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) PIN_8 PF18476.1 KEG08639.1 - 7.8 6.3 18.0 5.8 6.7 5.2 2.8 2 1 1 3 3 3 0 PIN like domain TetR_C_13 PF16925.5 KEG08639.1 - 9.2 6.2 8.5 60 3.6 0.1 3.7 2 1 3 5 5 5 0 Tetracyclin repressor-like, C-terminal domain PseudoU_synth_1 PF01416.20 KEG08640.1 - 1.2e-14 54.7 0.0 5e-12 46.2 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 KEG08641.1 - 4e-18 65.5 8.4 3.5e-05 24.5 0.8 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.11 KEG08641.1 - 0.2 11.5 0.1 5.6 6.8 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Pox_Ag35 PF03286.14 KEG08643.1 - 1.4 8.7 4.8 2.2 8.0 4.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trypan_PARP PF05887.11 KEG08643.1 - 6.9 6.7 17.0 12 5.9 17.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 KEG08644.1 - 0.11 12.5 3.1 0.16 11.9 3.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SCO1-SenC PF02630.14 KEG08645.1 - 1.7e-46 157.5 0.0 2.5e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KEG08645.1 - 0.00051 20.0 0.0 0.0019 18.1 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KEG08645.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like T6SS-SciN PF12790.7 KEG08645.1 - 0.12 12.1 0.2 0.32 10.7 0.1 1.6 2 0 0 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 CRF PF00473.17 KEG08645.1 - 1.4 9.1 3.2 4.3 7.5 3.2 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family DUF188 PF02639.14 KEG08646.1 - 0.67 9.6 0.0 0.67 9.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized BCR, YaiI/YqxD family COG1671 CPSase_L_D2 PF02786.17 KEG08647.1 - 3.3e-103 343.7 0.6 3e-78 262.2 0.2 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KEG08647.1 - 1.5e-46 157.4 0.0 3.4e-46 156.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KEG08647.1 - 8e-43 146.4 0.0 1.9e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KEG08647.1 - 3.7e-33 114.5 0.0 1.3e-32 112.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KEG08647.1 - 4.1e-22 78.6 0.5 1.9e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.19 KEG08647.1 - 3.9e-15 56.0 0.0 3.3e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Arginosuccinate synthase Dala_Dala_lig_C PF07478.13 KEG08647.1 - 2.4e-14 53.3 0.4 5e-06 26.2 0.2 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KEG08647.1 - 5.5e-13 48.8 0.0 2e-07 30.8 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 KEG08647.1 - 2.8e-07 30.6 0.0 1.4e-06 28.4 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.13 KEG08647.1 - 3.3e-07 30.3 0.7 1.1e-05 25.4 0.7 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KEG08647.1 - 5.9e-05 22.9 0.2 0.0011 18.8 0.0 2.6 2 0 0 2 2 2 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 KEG08647.1 - 0.00025 21.1 0.1 0.0092 16.0 0.0 2.7 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.16 KEG08647.1 - 0.012 15.1 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain TrkA_N PF02254.18 KEG08647.1 - 0.11 12.7 0.2 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Amidohydro_1 PF01979.20 KEG08648.1 - 6.2e-15 55.3 1.7 7.5e-15 55.1 1.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.21 KEG08648.1 - 0.011 15.1 2.2 0.032 13.6 1.7 1.9 2 1 0 2 2 2 0 TatD related DNase NDUF_B7 PF05676.13 KEG08648.1 - 0.076 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Amidohydro_2 PF04909.14 KEG08648.1 - 0.2 11.4 8.1 1.5 8.5 8.0 2.3 2 1 0 2 2 2 0 Amidohydrolase OMPdecase PF00215.24 KEG08649.1 - 5.2e-31 108.0 0.0 5.8e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Phage_Coat_Gp8 PF05371.12 KEG08649.1 - 0.027 14.2 0.6 0.07 12.9 0.6 1.7 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Methyltransf_24 PF13578.6 KEG08649.1 - 0.16 13.0 0.1 1.5 9.9 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Amastin PF07344.11 KEG08650.1 - 3.2e-34 118.0 16.1 3.9e-34 117.7 16.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KEG08650.1 - 0.00065 19.6 13.8 0.00094 19.1 13.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Cation_ATPase_C PF00689.21 KEG08650.1 - 0.13 12.0 14.2 0.18 11.5 14.2 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Amastin PF07344.11 KEG08651.1 - 1.6e-25 89.8 8.0 2e-25 89.4 8.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amidase02_C PF12123.8 KEG08652.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase PHD PF00628.29 KEG08653.1 - 2.2e-06 27.4 9.2 4.7e-06 26.4 9.2 1.6 1 0 0 1 1 1 1 PHD-finger Acetyltransf_10 PF13673.7 KEG08653.1 - 8.8e-06 25.7 0.1 0.059 13.3 0.0 2.5 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEG08653.1 - 3.3e-05 24.2 0.0 6.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 KEG08653.1 - 9.5e-05 22.4 3.7 9.5e-05 22.4 3.7 1.9 2 0 0 2 2 2 1 PHD-finger Acetyltransf_1 PF00583.25 KEG08653.1 - 0.013 15.8 0.2 0.35 11.1 0.3 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family zf-UDP PF14569.6 KEG08653.1 - 0.018 15.2 3.6 0.041 14.0 3.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger TPR_2 PF07719.17 KEG08654.1 - 0.00053 19.9 0.4 0.74 10.1 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG08654.1 - 0.0018 18.0 0.4 2.1 8.3 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Fam20C PF06702.12 KEG08654.1 - 0.0072 16.2 0.1 0.031 14.1 0.1 1.9 2 0 0 2 2 2 1 Golgi casein kinase, C-terminal, Fam20 PI3_PI4_kinase PF00454.27 KEG08654.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TPR_12 PF13424.6 KEG08654.1 - 0.011 16.0 1.5 1.3 9.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat 3HCDH PF00725.22 KEG08655.1 - 2.7e-08 34.3 0.1 0.00016 22.2 0.1 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 KEG08655.1 - 0.00024 20.5 0.1 0.00067 19.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Mito_fiss_reg PF05308.11 KEG08655.1 - 0.032 14.3 4.1 0.08 13.0 4.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KEG08655.1 - 0.34 11.0 9.7 1.1 9.2 9.7 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KEG08655.1 - 0.65 9.4 9.2 1.1 8.7 9.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MAGE_N PF12440.8 KEG08655.1 - 6.8 7.4 9.5 40 5.0 9.5 2.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Drc1-Sld2 PF11719.8 KEG08656.1 - 2.1e-07 30.9 0.8 0.015 14.8 0.2 2.2 2 0 0 2 2 2 2 DNA replication and checkpoint protein DUF4477 PF14780.6 KEG08656.1 - 0.04 13.5 0.1 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DUF4715 PF15835.5 KEG08656.1 - 0.082 13.0 0.1 0.64 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Ank_3 PF13606.6 KEG08657.1 - 2.8e-07 30.3 0.0 0.026 15.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KEG08657.1 - 3.7e-06 27.4 0.0 0.00011 22.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG08657.1 - 1.8e-05 25.2 0.0 0.17 12.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEG08657.1 - 2.1e-05 24.7 0.0 0.007 16.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.21 KEG08658.1 - 3.1e-50 171.4 0.0 3.7e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEG08658.1 - 9e-05 21.9 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEG08658.1 - 0.0027 16.7 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEG08658.1 - 0.0078 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase B5 PF03484.15 KEG08658.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetase B5 domain NPL PF17800.1 KEG08659.1 - 1.1e-11 45.2 0.0 1.1e-11 45.2 0.0 2.5 2 1 0 2 2 2 1 Nucleoplasmin-like domain FeS_assembly_P PF01883.19 KEG08660.1 - 2.5e-10 40.4 0.0 6.1e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein RRM_1 PF00076.22 KEG08661.1 - 4.4e-10 39.3 0.4 0.0015 18.3 0.0 4.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.15 KEG08661.1 - 0.0033 17.0 0.1 0.01 15.4 0.1 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region PGDH_C PF16896.5 KEG08661.1 - 0.15 12.0 0.3 0.31 11.0 0.3 1.4 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term N_formyltrans_C PF18216.1 KEG08665.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Prefoldin_2 PF01920.20 KEG08666.1 - 1.7e-13 50.4 18.3 4.6e-12 45.8 18.0 2.2 1 1 0 1 1 1 1 Prefoldin subunit TRAF_BIRC3_bd PF16673.5 KEG08666.1 - 2 8.2 7.8 0.099 12.5 2.1 1.8 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain CENP-H PF05837.12 KEG08666.1 - 6.3 7.2 15.2 15 6.1 8.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) LRR_4 PF12799.7 KEG08667.1 - 5.2e-31 106.2 7.9 8.5e-07 29.2 0.4 6.4 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG08667.1 - 8.7e-19 67.0 13.3 4.4e-08 32.8 0.4 5.7 3 1 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KEG08667.1 - 6.1e-18 64.9 8.7 9.3e-06 25.2 0.5 4.3 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 KEG08667.1 - 6.9e-07 28.8 4.4 0.84 9.9 0.0 8.0 10 0 0 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.33 KEG08667.1 - 0.0013 19.0 14.5 19 6.3 0.0 8.6 10 0 0 10 10 10 1 Leucine Rich Repeat Peptidase_M17 PF00883.21 KEG08670.1 - 8.1e-102 340.7 0.0 1.1e-101 340.3 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KEG08670.1 - 0.00088 19.1 2.1 0.0023 17.8 0.7 2.4 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain CHB_HEX_C_1 PF13290.6 KEG08671.1 - 3e-08 33.5 2.3 6.9e-05 22.8 0.1 3.2 2 1 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 KEG08671.1 - 3.3e-07 30.4 1.3 0.0046 17.1 0.0 3.8 2 1 0 2 2 2 2 Fn3 associated TerB PF05099.13 KEG08672.1 - 0.00017 21.6 0.2 0.00031 20.7 0.1 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TerB DUF533 PF04391.12 KEG08672.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SpecificRecomb PF10136.9 KEG08676.1 - 0.26 9.6 0.0 0.39 9.0 0.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase Fringe PF02434.16 KEG08677.1 - 9.3e-05 22.0 1.5 0.0012 18.3 1.5 2.2 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KEG08677.1 - 0.12 11.7 0.3 0.19 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 CENP-R PF06729.12 KEG08678.1 - 0.0058 16.6 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component, CENP-R LIN37 PF15306.6 KEG08680.1 - 0.031 14.5 0.4 0.043 14.1 0.4 1.2 1 0 0 1 1 1 0 LIN37 Plasmid_RAQPRD PF09686.10 KEG08680.1 - 0.064 13.5 1.8 0.091 13.0 1.8 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LamB_YcsF PF03746.16 KEG08681.1 - 0.083 12.6 0.5 0.11 12.1 0.5 1.1 1 0 0 1 1 1 0 LamB/YcsF family ASD2 PF08687.11 KEG08686.1 - 0.038 13.5 4.2 0.055 13.0 4.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 YabA PF06156.13 KEG08686.1 - 0.04 14.6 5.1 0.04 14.6 5.1 1.8 1 1 1 2 2 2 0 Initiation control protein YabA Poty_PP PF08440.10 KEG08686.1 - 0.086 11.9 3.0 0.13 11.3 3.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein FapA PF03961.13 KEG08686.1 - 0.14 10.8 4.6 0.17 10.5 4.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tho2 PF11262.8 KEG08686.1 - 0.14 11.3 5.3 0.21 10.8 5.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3450 PF11932.8 KEG08686.1 - 0.28 10.4 15.3 0.35 10.1 14.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 KEG08686.1 - 0.42 10.8 8.7 0.67 10.2 8.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 KEG08686.1 - 0.47 10.7 1.5 0.8 10.0 1.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Osmo_CC PF08946.10 KEG08686.1 - 0.5 10.7 3.6 3.2 8.1 0.6 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil ZapB PF06005.12 KEG08686.1 - 2.9 8.4 13.8 0.93 10.0 6.9 2.2 2 0 0 2 2 2 0 Cell division protein ZapB TMPIT PF07851.13 KEG08686.1 - 3.3 6.9 8.0 4.6 6.4 8.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 KEG08686.1 - 8 6.8 9.7 1.9 8.8 5.9 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 RRM_1 PF00076.22 KEG08687.1 - 3.2e-14 52.5 0.0 5.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Roughex PF06020.11 KEG08687.1 - 0.4 9.7 5.6 0.63 9.1 5.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein MAP65_ASE1 PF03999.12 KEG08687.1 - 0.98 8.0 5.2 1.4 7.5 5.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Kinesin PF00225.23 KEG08688.1 - 8.8e-83 278.0 2.3 3.2e-82 276.1 0.0 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08688.1 - 1.2e-26 93.4 0.3 4.6e-24 85.0 0.1 2.8 3 0 0 3 3 3 2 Microtubule binding ABC_trans_N PF14510.6 KEG08688.1 - 0.12 13.0 3.4 0.19 12.4 0.9 2.8 2 0 0 2 2 2 0 ABC-transporter N-terminal Tubulin PF00091.25 KEG08696.1 - 3.4e-69 233.0 0.0 5.3e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEG08696.1 - 7.8e-41 139.2 0.0 1.2e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KEG08696.1 - 3.2e-05 24.2 0.0 7.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KEG08696.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KEG08696.1 - 0.0051 16.1 0.1 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Tubulin PF00091.25 KEG08697.1 - 5.9e-65 219.2 0.0 8.4e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEG08697.1 - 6.6e-50 168.5 0.1 1.1e-49 167.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KEG08697.1 - 0.036 13.8 0.0 0.091 12.4 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain DUF1935 PF09149.10 KEG08698.1 - 5.5e-28 97.4 0.0 6.5e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Thioredoxin_8 PF13905.6 KEG08699.1 - 0.00014 22.1 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF1935 PF09149.10 KEG08700.1 - 1.5e-38 131.3 0.1 1.8e-38 131.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF948 PF06103.11 KEG08701.1 - 0.024 14.9 0.6 0.024 14.9 0.6 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) GT-D PF08759.11 KEG08701.1 - 0.032 13.9 2.3 0.037 13.7 0.1 2.0 3 0 0 3 3 3 0 Glycosyltransferase GT-D fold HisKA_3 PF07730.13 KEG08701.1 - 1.3 9.6 0.0 1.3 9.6 0.0 4.8 2 1 2 5 5 5 0 Histidine kinase Mucin PF01456.17 KEG08704.1 - 0.02 14.9 18.1 0.02 14.9 18.1 3.8 3 2 0 3 3 3 0 Mucin-like glycoprotein Phage_tail_2 PF06199.11 KEG08704.1 - 0.83 9.8 3.5 0.35 11.0 0.6 1.8 2 0 0 2 2 2 0 Phage tail tube protein Ribosomal_L5 PF00281.19 KEG08705.1 - 0.88 10.0 4.7 14 6.1 0.1 3.6 3 0 0 3 3 3 0 Ribosomal protein L5 Apo-CIII PF05778.12 KEG08705.1 - 1.2 8.8 6.3 0.76 9.5 0.6 3.1 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) Mucin PF01456.17 KEG08705.1 - 1.5 8.8 51.7 0.023 14.7 14.3 3.6 1 1 1 3 3 3 0 Mucin-like glycoprotein KI67R PF08065.12 KEG08705.1 - 3.9 8.0 14.0 2.9 8.5 0.0 3.1 2 2 0 2 2 2 0 KI67R (NUC007) repeat DUF2009 PF09418.10 KEG08706.1 - 0.0032 16.6 4.9 0.0042 16.2 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) cpYpsA PF12694.7 KEG08706.1 - 0.33 10.7 4.0 13 5.5 0.2 3.0 2 1 1 3 3 3 0 Circularly permutated YpsA SLOG family FUSC PF04632.12 KEG08706.1 - 4.8 5.6 5.5 1.8 7.0 0.2 2.3 2 1 0 2 2 2 0 Fusaric acid resistance protein family DUF948 PF06103.11 KEG08706.1 - 5 7.5 11.8 3.4 8.0 6.2 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4366 PF14283.6 KEG08706.1 - 5.2 7.1 9.1 0.65 10.0 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2009 PF09418.10 KEG08707.1 - 0.091 11.8 11.7 0.012 14.7 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) cpYpsA PF12694.7 KEG08707.1 - 1.1 9.0 5.3 17 5.2 0.3 3.2 2 2 1 3 3 3 0 Circularly permutated YpsA SLOG family DUF948 PF06103.11 KEG08707.1 - 5.7 7.3 14.3 24 5.3 8.5 3.8 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 KEG08707.1 - 9.4 4.6 7.5 2.2 6.7 0.2 2.5 2 1 1 3 3 3 0 Fusaric acid resistance protein family SUIM_assoc PF16619.5 KEG08708.1 - 3.6e-05 23.8 0.0 0.27 11.3 0.0 3.7 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF3138 PF11336.8 KEG08708.1 - 7.3 5.1 5.7 0.7 8.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) zf-DBF PF07535.12 KEG08709.1 - 1.2 9.3 6.1 2.9 8.1 6.1 1.7 1 0 0 1 1 1 0 DBF zinc finger DUF4482 PF14818.6 KEG08709.1 - 2 9.3 0.0 2 9.3 0.0 4.1 5 1 0 6 6 6 0 Domain of unknown function (DUF4482) 3HCDH PF00725.22 KEG08710.1 - 0.077 13.6 0.1 0.17 12.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AAA PF00004.29 KEG08711.1 - 9.9e-09 35.7 0.0 5.3e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KEG08711.1 - 1e-05 25.4 0.6 3.1e-05 23.8 0.6 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG08711.1 - 3.3e-05 24.2 0.0 8.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEG08711.1 - 0.00021 21.3 0.0 0.00048 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEG08711.1 - 0.00022 20.9 0.2 0.00068 19.3 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG08711.1 - 0.00032 20.9 0.1 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEG08711.1 - 0.00034 20.4 0.0 0.00081 19.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG08711.1 - 0.00055 20.2 0.1 0.0054 17.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG08711.1 - 0.00065 20.1 2.5 0.0016 18.9 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KEG08711.1 - 0.00093 19.8 0.0 0.0041 17.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_assoc_2 PF16193.5 KEG08711.1 - 0.0011 19.2 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain IstB_IS21 PF01695.17 KEG08711.1 - 0.0021 17.8 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 KEG08711.1 - 0.0055 17.0 0.1 0.04 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEG08711.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KEG08711.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KEG08711.1 - 0.041 13.6 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEG08711.1 - 0.043 13.7 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 KEG08711.1 - 0.057 13.9 0.0 0.22 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KEG08711.1 - 0.058 13.8 0.3 0.22 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain TOM13 PF08219.11 KEG08711.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein TOM13 AAA_7 PF12775.7 KEG08711.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Kelch_4 PF13418.6 KEG08712.1 - 1.5e-20 72.9 4.1 0.0033 17.4 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG08712.1 - 3.4e-14 52.4 3.2 0.0078 16.2 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KEG08712.1 - 4.6e-12 45.9 4.2 0.64 10.4 0.0 7.0 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG08712.1 - 0.00015 22.0 5.8 0.65 10.4 0.1 5.0 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 KEG08712.1 - 0.00019 21.0 11.5 0.01 15.4 0.4 4.8 5 0 0 5 5 5 2 Kelch motif DUF4113 PF13438.6 KEG08713.1 - 0.21 11.7 0.2 0.21 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Pkinase PF00069.25 KEG08715.1 - 3e-48 164.5 0.0 4.4e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08715.1 - 1.2e-35 123.1 0.0 2.1e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SP_C-Propep PF08999.10 KEG08715.1 - 1.9 8.3 7.8 16 5.3 3.9 2.5 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Metallophos PF00149.28 KEG08716.1 - 1.3e-10 42.1 0.1 2.6e-10 41.2 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 KEG08716.1 - 0.00073 18.7 0.0 0.0028 16.7 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase AlbA_2 PF04326.14 KEG08717.1 - 0.0025 18.1 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain zf-RING_7 PF02591.15 KEG08717.1 - 0.13 12.4 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 C4-type zinc ribbon domain Dala_Dala_lig_C PF07478.13 KEG08720.1 - 6.3e-12 45.5 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 KEG08720.1 - 1.9e-10 41.4 0.0 3.4e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 SET domain ATP-grasp PF02222.22 KEG08720.1 - 6.6e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KEG08720.1 - 0.00011 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KEG08720.1 - 0.0016 18.1 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KEG08720.1 - 0.019 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain zf_Rg PF17915.1 KEG08720.1 - 9.5 5.7 7.0 1.2 8.6 0.5 2.5 3 0 0 3 3 3 0 Reverse gyrase zinc finger 3HCDH PF00725.22 KEG08723.1 - 0.0098 16.5 0.2 0.06 14.0 0.1 2.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PPR_long PF17177.4 KEG08723.1 - 0.022 14.1 3.9 1.4 8.2 0.0 3.6 4 0 0 4 4 4 0 Pentacotripeptide-repeat region of PRORP TPR_10 PF13374.6 KEG08723.1 - 0.076 12.9 0.5 6.7 6.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG08723.1 - 0.72 10.0 5.1 72 3.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.28 KEG08724.1 - 1.4e-28 100.9 0.0 2.8e-28 99.8 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase FAM183 PF14886.6 KEG08726.1 - 0.0013 19.4 0.4 0.0027 18.4 0.4 1.8 1 1 0 1 1 1 1 FAM183A and FAM183B related DFF-C PF09033.10 KEG08726.1 - 0.058 13.3 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain LLC1 PF14945.6 KEG08726.1 - 0.14 12.8 2.2 0.75 10.4 2.2 1.9 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein SPC22 PF04573.12 KEG08727.1 - 1e-27 96.7 0.0 1.2e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit LCIB_C_CA PF18599.1 KEG08728.1 - 5.1 6.3 9.4 0.2 10.9 0.9 2.6 3 0 0 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases IFP_35_N PF07334.13 KEG08728.1 - 5.1 7.2 8.0 6.1 7.0 0.1 3.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlxA PF14282.6 KEG08731.1 - 0.0063 16.5 7.8 0.0079 16.2 7.8 1.3 1 0 0 1 1 1 1 FlxA-like protein SLIDE PF09111.10 KEG08731.1 - 0.055 13.5 1.6 0.072 13.1 1.6 1.2 1 0 0 1 1 1 0 SLIDE Hemagglutinin PF00509.18 KEG08731.1 - 0.11 10.8 0.9 0.13 10.7 0.9 1.0 1 0 0 1 1 1 0 Haemagglutinin STAT_bind PF02864.15 KEG08731.1 - 0.12 12.9 2.1 0.15 12.6 2.1 1.2 1 0 0 1 1 1 0 STAT protein, DNA binding domain VPS38 PF17649.1 KEG08731.1 - 0.24 10.2 3.1 0.26 10.1 3.1 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF2087 PF09860.9 KEG08731.1 - 0.26 11.4 2.2 1.6 8.9 1.0 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) FERM_M PF00373.18 KEG08731.1 - 0.38 11.2 2.0 0.58 10.6 2.0 1.3 1 0 0 1 1 1 0 FERM central domain GNT-I PF03071.15 KEG08731.1 - 1.2 7.8 5.1 1.3 7.7 5.1 1.0 1 0 0 1 1 1 0 GNT-I family Ion_trans_2 PF07885.16 KEG08732.1 - 2.4e-11 43.5 5.9 2.4e-11 43.5 5.9 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KEG08732.1 - 0.0057 15.9 1.5 0.017 14.4 1.4 1.9 1 1 0 1 1 1 1 Ion transport protein CitMHS PF03600.16 KEG08732.1 - 0.0064 15.7 0.3 0.0095 15.2 0.3 1.3 1 0 0 1 1 1 1 Citrate transporter Ion_trans_2 PF07885.16 KEG08733.1 - 7.3e-12 45.1 6.3 2.5e-11 43.4 6.3 2.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KEG08733.1 - 0.00015 21.1 1.3 0.00015 21.1 1.3 2.2 1 1 1 2 2 2 1 Ion transport protein Trigger_C PF05698.14 KEG08733.1 - 0.012 15.7 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Lig_chan PF00060.26 KEG08733.1 - 0.086 12.7 0.7 0.24 11.2 0.7 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel HPPK PF01288.20 KEG08733.1 - 0.14 12.7 0.1 0.49 10.9 0.0 1.9 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF2884 PF11101.8 KEG08734.1 - 0.078 12.5 1.3 0.12 11.8 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DDRGK PF09756.9 KEG08734.1 - 0.11 12.1 5.5 0.25 10.9 5.5 1.5 1 0 0 1 1 1 0 DDRGK domain Tetraspanin PF00335.20 KEG08735.1 - 1e-13 51.5 4.7 1.5e-13 51.0 4.7 1.2 1 0 0 1 1 1 1 Tetraspanin family UCH PF00443.29 KEG08737.1 - 5.8e-42 144.0 0.0 1e-41 143.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG08737.1 - 1.1e-18 67.9 0.4 5.2e-17 62.4 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 KEG08737.1 - 0.0014 17.9 1.0 0.0014 17.9 1.0 2.9 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Blt1 PF12754.7 KEG08737.1 - 0.0051 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Blt1 N-terminal domain MAGE_N PF12440.8 KEG08737.1 - 1.4 9.7 6.3 9.2 7.0 6.3 2.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal CFEM PF05730.11 KEG08737.1 - 4 7.6 7.5 6.6 6.9 1.9 3.0 2 0 0 2 2 2 0 CFEM domain TAL_FSA PF00923.19 KEG08739.1 - 5.1e-19 68.7 0.0 5.6e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Arteri_nsp7a PF16749.5 KEG08740.1 - 0.082 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha Sec63 PF02889.16 KEG08741.1 - 3.9e-140 465.3 2.2 1.2e-75 254.0 0.3 2.5 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 KEG08741.1 - 2.8e-51 173.7 0.0 7.3e-28 97.5 0.4 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KEG08741.1 - 7.8e-27 94.3 0.0 1.3e-17 64.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEG08741.1 - 1.8e-17 63.7 0.1 2.2e-08 34.4 0.0 4.1 3 2 0 3 3 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEG08741.1 - 1.5e-08 35.0 0.1 0.00022 21.5 0.1 3.7 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEG08741.1 - 2.1e-08 34.1 0.0 0.00094 18.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEG08741.1 - 7.7e-08 32.8 0.5 2.8e-05 24.5 0.2 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KEG08741.1 - 0.00011 21.4 0.0 0.067 12.2 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 KEG08741.1 - 0.00034 20.4 0.0 0.0096 15.6 0.1 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KEG08741.1 - 0.0016 17.7 0.0 0.0061 15.8 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KEG08741.1 - 0.0063 16.0 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 KEG08741.1 - 0.022 14.3 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KEG08741.1 - 0.038 14.4 2.8 1.1 9.7 0.2 4.0 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KEG08741.1 - 0.061 12.7 0.1 9.3 5.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein UvrD-helicase PF00580.21 KEG08741.1 - 0.062 12.8 0.9 0.68 9.4 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF1796 PF08795.10 KEG08741.1 - 0.09 12.7 1.7 2 8.3 0.1 3.1 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) His_Phos_1 PF00300.22 KEG08742.1 - 3.3e-05 23.7 0.0 0.22 11.2 0.0 3.0 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) Peptidase_M8 PF01457.16 KEG08744.1 - 2.6e-34 118.8 0.7 3.1e-34 118.6 0.7 1.0 1 0 0 1 1 1 1 Leishmanolysin RHSP PF07999.11 KEG08745.1 - 5e-26 91.5 0.0 6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein PLDc_2 PF13091.6 KEG08748.1 - 5.3e-10 39.3 0.0 0.0003 20.7 0.0 3.2 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KEG08748.1 - 0.0037 17.4 1.2 0.04 14.1 0.1 2.8 2 1 0 2 2 2 1 Phospholipase D Active site motif PTPA PF03095.15 KEG08749.1 - 1.7e-102 343.0 0.0 2e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Myosin_TH1 PF06017.13 KEG08750.1 - 0.059 13.1 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding TMEM171 PF15471.6 KEG08750.1 - 8 5.4 13.8 0.94 8.4 2.5 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 NUDE_C PF04880.13 KEG08751.1 - 0.26 11.7 1.0 0.6 10.6 0.4 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Peptidase_M15_2 PF05951.13 KEG08754.1 - 1.3 8.6 3.6 25 4.5 0.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF882) Cas_APE2256 PF09651.10 KEG08754.1 - 1.8 8.4 6.3 38 4.2 0.2 3.2 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_APE2256) PRD1_DD PF11087.8 KEG08754.1 - 3.3 7.5 23.6 1.9 8.2 0.5 4.7 4 1 1 5 5 5 0 PRD1 phage membrane DNA delivery X8 PF07983.13 KEG08754.1 - 7.1 7.4 16.3 16 6.3 0.2 5.1 2 1 4 6 6 6 0 X8 domain Galactosyl_T PF01762.21 KEG08755.1 - 2.3e-07 30.9 0.4 0.0086 15.9 0.1 3.0 3 1 0 3 3 3 2 Galactosyltransferase DUF4351 PF14261.6 KEG08758.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) NDK PF00334.19 KEG08759.1 - 6e-54 181.7 0.0 7.2e-54 181.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.23 KEG08760.1 - 1.9e-95 318.2 0.0 2.9e-95 317.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEG08760.1 - 2.8e-26 91.8 2.8 7.2e-26 90.5 1.9 2.0 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KEG08760.1 - 3.2e-21 75.5 1.2 7.2e-21 74.4 0.4 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KEG08760.1 - 2.9e-09 37.5 0.6 7.1e-09 36.2 0.3 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KEG08760.1 - 3.4e-07 30.3 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEG08760.1 - 3.5e-05 23.3 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_lid_2 PF17863.1 KEG08760.1 - 0.02 14.7 0.3 0.047 13.5 0.3 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 KEG08760.1 - 0.044 13.6 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Spc29 PF17082.5 KEG08761.1 - 0.16 11.8 8.9 0.34 10.7 7.1 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 ATG16 PF08614.11 KEG08761.1 - 0.38 11.0 28.8 0.24 11.6 10.6 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) XLF PF09302.11 KEG08761.1 - 0.52 10.5 9.8 3.3 7.8 5.3 3.0 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component HWE_HK PF07536.14 KEG08761.1 - 0.73 10.6 8.3 1.7 9.4 0.0 4.0 4 0 0 4 4 4 0 HWE histidine kinase Herpes_BLRF2 PF05812.12 KEG08761.1 - 1.1 9.5 16.7 4.8 7.3 9.4 3.6 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein Peptidase_S49_N PF08496.10 KEG08761.1 - 8.2 6.5 15.6 0.24 11.5 5.8 2.7 2 1 1 3 3 3 0 Peptidase family S49 N-terminal TBCA PF02970.16 KEG08763.1 - 1.6e-19 70.0 3.3 2.1e-19 69.6 3.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DAPDH_C PF16654.5 KEG08763.1 - 0.051 13.4 0.2 0.058 13.2 0.2 1.1 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain Thioredoxin PF00085.20 KEG08764.1 - 3.1e-08 33.5 0.0 4.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KEG08764.1 - 8.1e-08 31.5 0.2 9.3e-08 31.3 0.2 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_6 PF13848.6 KEG08764.1 - 0.0037 17.2 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KEG08764.1 - 0.03 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.16 KEG08764.1 - 0.035 13.9 0.9 0.054 13.3 0.2 1.6 2 0 0 2 2 2 0 Mitosis protein DIM1 KaiB PF07689.12 KEG08764.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiB domain DUF465 PF04325.13 KEG08764.1 - 0.2 11.7 4.0 0.33 11.0 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF3833 PF12915.7 KEG08765.1 - 0.031 13.8 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) Laminin_I PF06008.14 KEG08765.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain I KASH PF10541.9 KEG08765.1 - 0.13 12.6 1.2 0.21 11.9 0.4 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain PfkB PF00294.24 KEG08766.1 - 6.2e-42 143.9 0.0 8.8e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HZS_alpha PF18582.1 KEG08766.1 - 0.13 12.7 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain Complex1_LYR PF05347.15 KEG08767.1 - 9.8e-10 38.3 0.5 1.3e-09 37.9 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3336 PF11815.8 KEG08768.1 - 4.6e-21 75.0 0.1 6.9e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEG08768.1 - 3.2e-11 43.8 0.2 5.3e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4140 PF13600.6 KEG08769.1 - 0.0078 16.6 1.9 0.0078 16.6 1.9 4.8 4 2 0 4 4 4 1 N-terminal domain of unknown function (DUF4140) Mucin PF01456.17 KEG08772.1 - 0.0047 16.9 0.2 0.0067 16.4 0.2 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Ribosomal_60s PF00428.19 KEG08774.1 - 0.18 12.4 22.8 0.07 13.7 19.8 1.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.13 KEG08774.1 - 3.1 6.7 8.4 3.2 6.7 8.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GARP PF16731.5 KEG08774.1 - 3.7 7.2 31.9 0.14 11.8 9.0 2.1 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF3824 PF12868.7 KEG08774.1 - 4.6 7.9 17.7 0.16 12.7 11.5 1.7 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF948 PF06103.11 KEG08775.1 - 0.012 15.8 5.5 0.086 13.1 5.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 KEG08775.1 - 0.027 13.8 7.9 0.04 13.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2524 PF10732.9 KEG08775.1 - 0.049 14.0 3.7 0.12 12.7 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) MotY_N PF18393.1 KEG08775.1 - 0.073 13.2 0.9 0.12 12.4 0.8 1.4 1 1 0 1 1 1 0 MotY N-terminal domain DegS PF05384.11 KEG08775.1 - 0.096 12.2 4.3 0.066 12.7 2.1 1.9 2 0 0 2 2 2 0 Sensor protein DegS HOOK PF05622.12 KEG08775.1 - 0.096 10.8 11.9 0.022 12.9 8.8 1.5 1 1 1 2 2 2 0 HOOK protein Spc7 PF08317.11 KEG08775.1 - 0.2 10.5 6.7 0.25 10.2 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KEG08775.1 - 0.37 8.7 3.5 0.4 8.5 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.9 KEG08775.1 - 0.96 10.2 6.7 1.1 9.9 5.6 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) NARP1 PF12569.8 KEG08775.1 - 1.8 7.4 13.1 0.68 8.8 10.9 1.4 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 DUF2205 PF10224.9 KEG08775.1 - 5.1 7.2 7.9 6.8 6.8 6.3 2.1 2 1 0 2 2 2 0 Short coiled-coil protein YebO PF13974.6 KEG08775.1 - 7.2 6.8 7.8 10 6.3 6.7 1.7 1 1 0 1 1 1 0 YebO-like protein Mucin PF01456.17 KEG08776.1 - 6.7 6.7 12.7 0.13 12.3 4.2 2.3 2 2 0 2 2 2 0 Mucin-like glycoprotein ALS2CR11 PF15729.5 KEG08778.1 - 0.091 11.9 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Ribosomal_L22 PF00237.19 KEG08780.1 - 1.6e-23 82.9 0.1 1.8e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WWE PF02825.20 KEG08783.1 - 4.1e-11 43.3 0.0 8.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 WWE domain DUF4865 PF16157.5 KEG08784.1 - 0.016 15.2 0.1 0.082 12.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4865) Plasmodium_Vir PF05795.11 KEG08784.1 - 0.053 12.9 0.1 0.083 12.3 0.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pup PF05639.11 KEG08784.1 - 9.5 7.2 7.5 3 8.8 2.5 2.8 2 0 0 2 2 2 0 Pup-like protein zf-RING_2 PF13639.6 KEG08785.1 - 1.4e-06 28.5 3.5 1.4e-06 28.5 3.5 4.0 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KEG08785.1 - 4.4e-05 23.4 1.0 4.4e-05 23.4 1.0 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 KEG08785.1 - 5.6e-05 22.8 4.5 0.00022 20.9 4.5 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEG08785.1 - 0.00014 21.6 2.0 0.00014 21.6 2.0 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG08785.1 - 0.00045 20.0 0.5 0.00045 20.0 0.5 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3592 PF12158.8 KEG08786.1 - 3e-08 33.9 0.4 3.9e-08 33.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.6 KEG08787.1 - 7e-19 68.1 1.5 1.1e-18 67.5 1.5 1.3 1 0 0 1 1 1 1 Calmodulin-binding DUF4795 PF16043.5 KEG08787.1 - 0.033 13.8 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TPD52 PF04201.15 KEG08787.1 - 0.073 12.7 0.4 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Phage_tail_S PF05069.13 KEG08789.1 - 0.26 11.1 9.1 0.33 10.8 7.6 1.9 1 1 0 1 1 1 0 Phage virion morphogenesis family SUIM_assoc PF16619.5 KEG08789.1 - 0.55 10.3 5.8 2 8.6 5.8 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 R_equi_Vir PF05526.11 KEG08789.1 - 2.5 7.9 4.2 28 4.5 1.0 2.3 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein SKA1 PF07160.12 KEG08789.1 - 5 6.9 9.6 1.4 8.7 6.7 1.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Spt20 PF12090.8 KEG08789.1 - 6 6.4 7.8 9.7 5.7 7.8 1.3 1 0 0 1 1 1 0 Spt20 family GPR15L PF15854.5 KEG08790.1 - 0.52 10.6 7.3 0.88 9.8 7.3 1.5 1 1 0 1 1 1 0 G-protein coupled receptor ligand 15 RPA_C PF08784.11 KEG08791.1 - 3.8e-19 69.3 1.0 1.2e-18 67.6 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KEG08791.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GntR PF00392.21 KEG08791.1 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 KEG08791.1 - 0.0092 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain PaaX PF07848.12 KEG08791.1 - 0.035 14.3 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein Peptidase_C39 PF03412.15 KEG08791.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family E1-E2_ATPase PF00122.20 KEG08792.1 - 4e-48 163.3 1.4 4e-48 163.3 1.4 2.5 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEG08792.1 - 3.7e-44 150.6 6.1 3.7e-44 150.6 6.1 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEG08792.1 - 1.7e-20 74.2 1.2 2.9e-19 70.2 1.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEG08792.1 - 4.9e-20 71.0 0.4 1.6e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KEG08792.1 - 9.4e-16 57.7 0.2 2.3e-15 56.5 0.2 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEG08792.1 - 1.4e-08 34.8 0.8 2.5e-06 27.4 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEG08792.1 - 0.00015 22.3 0.0 0.00038 20.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 KEG08792.1 - 1.6 8.8 6.1 1.3 9.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Ribosomal_L9_N PF01281.19 KEG08793.1 - 2.7e-06 26.8 0.0 5.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain ABC1 PF03109.16 KEG08794.1 - 1.4e-29 102.7 0.0 4e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 KEG08794.1 - 6.5e-06 26.2 0.2 1.2e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KEG08794.1 - 0.014 14.8 0.0 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain HTH_28 PF13518.6 KEG08794.1 - 0.053 13.7 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain EcKinase PF02958.20 KEG08794.1 - 0.09 12.1 0.1 0.52 9.6 0.0 2.1 3 0 0 3 3 3 0 Ecdysteroid kinase ThiF PF00899.21 KEG08795.1 - 3.4e-59 200.2 0.4 5.9e-59 199.4 0.4 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KEG08795.1 - 2.4e-11 44.1 0.0 5.8e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KEG08795.1 - 2.3e-08 34.3 0.0 0.00045 20.2 0.0 2.4 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KEG08795.1 - 0.00022 21.6 0.3 0.002 18.6 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KEG08795.1 - 0.059 13.9 0.3 0.2 12.2 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KEG08795.1 - 0.087 12.9 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DnaJ_C PF01556.18 KEG08796.1 - 6.2e-37 127.0 0.1 1.1e-36 126.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG08796.1 - 7.2e-28 96.5 1.7 1.3e-27 95.7 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEG08796.1 - 3.6e-13 49.7 13.9 7.5e-13 48.7 13.9 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF2614 PF11023.8 KEG08796.1 - 0.092 12.8 1.1 0.13 12.3 0.4 1.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain Tnp_zf-ribbon_2 PF13842.6 KEG08796.1 - 0.18 12.7 3.0 0.25 12.2 0.9 2.2 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.7 KEG08796.1 - 0.18 11.9 5.6 3 7.9 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Anti-TRAP PF15777.5 KEG08796.1 - 0.48 10.4 6.3 4.1 7.4 0.9 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KEG08796.1 - 5.6 7.0 8.7 1.3 9.0 1.9 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 KEG08796.1 - 10 6.0 12.6 3.8 7.3 0.2 4.2 3 1 1 4 4 4 0 A2L zinc ribbon domain 4HBT PF03061.22 KEG08797.1 - 1e-05 25.8 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.22 KEG08798.1 - 9.9e-06 25.8 0.1 2.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Thioesterase superfamily TFIIA PF03153.13 KEG08799.1 - 2.3 8.1 19.0 0.34 10.9 15.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 KEG08799.1 - 5.2 7.1 8.3 13 5.8 8.3 1.6 1 1 0 1 1 1 0 Telomere-associated protein TERB2 PQQ_3 PF13570.6 KEG08800.1 - 0.074 13.6 3.6 0.24 11.9 0.3 3.1 2 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 KEG08800.1 - 0.13 13.2 6.6 2.2 9.3 0.3 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat FAM76 PF16046.5 KEG08805.1 - 0.0065 15.9 2.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 FAM76 protein HrpB7 PF09486.10 KEG08805.1 - 0.015 15.7 1.7 0.015 15.7 1.7 4.1 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 KEG08805.1 - 0.024 14.9 0.6 0.024 14.9 0.6 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Rx_N PF18052.1 KEG08805.1 - 0.26 11.6 2.0 0.81 10.0 2.0 1.8 1 0 0 1 1 1 0 Rx N-terminal domain SlyX PF04102.12 KEG08805.1 - 2.4 8.8 9.1 0.28 11.8 3.3 2.5 2 0 0 2 2 2 0 SlyX Abhydrolase_3 PF07859.13 KEG08806.1 - 3.2e-13 50.0 0.0 5.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEG08806.1 - 5.5e-10 38.7 0.0 1.2e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEG08806.1 - 1.2e-05 24.9 0.0 0.58 9.6 0.1 3.4 2 2 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEG08806.1 - 2e-05 25.3 0.5 3.1e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEG08806.1 - 0.0095 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PPI_Ypi1 PF07491.11 KEG08808.1 - 2.6e-15 56.0 9.6 6e-15 54.8 9.6 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor DUF755 PF05501.11 KEG08808.1 - 0.0084 16.4 7.9 0.0084 16.4 7.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF755) SR-25 PF10500.9 KEG08808.1 - 0.013 15.2 3.4 0.016 14.9 3.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 KEG08808.1 - 0.047 14.3 0.2 0.068 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) TSC22 PF01166.18 KEG08809.1 - 0.0004 20.6 4.3 0.0079 16.5 1.1 2.7 2 0 0 2 2 2 1 TSC-22/dip/bun family Vps54_N PF10475.9 KEG08809.1 - 0.11 11.8 0.2 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex CENP-H PF05837.12 KEG08809.1 - 0.28 11.6 6.8 0.08 13.3 1.3 2.7 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF2880 PF11082.8 KEG08809.1 - 0.32 11.3 1.8 24 5.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2880) DUF724 PF05266.14 KEG08809.1 - 0.45 10.3 1.9 2 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pkinase PF00069.25 KEG08810.1 - 2.8e-47 161.3 0.0 1e-24 87.4 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08810.1 - 1.4e-20 73.7 0.0 3.3e-16 59.3 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG08810.1 - 0.0066 15.8 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DZR PF12773.7 KEG08810.1 - 0.019 14.9 0.3 0.057 13.4 0.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon Kdo PF06293.14 KEG08810.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese_C PF12368.8 KEG08810.1 - 0.053 13.9 0.1 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Rhodanase C-terminal APH PF01636.23 KEG08810.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG08810.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-ribbon_3 PF13248.6 KEG08810.1 - 0.7 9.4 6.4 0.77 9.3 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.6 KEG08810.1 - 3.6 8.3 8.5 19 6.0 0.9 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 SNARE PF05739.19 KEG08811.1 - 0.0091 16.0 0.4 0.018 15.0 0.4 1.4 1 0 0 1 1 1 1 SNARE domain DGF-1_C PF11040.8 KEG08812.1 - 0.00027 20.9 1.6 0.00044 20.2 1.1 1.6 1 1 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2913 PF11140.8 KEG08812.1 - 0.044 13.5 0.7 0.065 13.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Spc7 PF08317.11 KEG08812.1 - 0.17 10.7 8.2 0.074 11.9 5.5 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Peptidase_M28 PF04389.17 KEG08813.1 - 2e-22 79.9 0.2 1.6e-07 31.2 0.3 3.2 3 0 0 3 3 3 3 Peptidase family M28 DUF863 PF05904.11 KEG08813.1 - 0.19 10.2 1.0 0.29 9.5 1.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) AFG1_ATPase PF03969.16 KEG08814.1 - 7.7e-84 281.6 2.1 2e-78 263.8 0.1 2.9 2 1 1 3 3 3 2 AFG1-like ATPase Bac_DnaA PF00308.18 KEG08814.1 - 0.0014 18.5 0.3 0.027 14.3 0.3 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_22 PF13401.6 KEG08814.1 - 0.004 17.4 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG08814.1 - 0.0067 16.8 0.0 0.031 14.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEG08814.1 - 0.01 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEG08814.1 - 0.034 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KEG08814.1 - 0.078 12.2 0.1 0.42 9.8 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KEG08814.1 - 0.12 12.2 0.0 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KEG08814.1 - 0.19 12.2 0.0 0.66 10.5 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Lectin_leg-like PF03388.13 KEG08815.1 - 1.8e-12 47.1 0.0 4.7e-05 22.8 0.0 3.3 4 0 0 4 4 4 2 Legume-like lectin family ASPRs PF17641.2 KEG08816.1 - 0.039 14.2 2.6 0.084 13.2 2.6 1.5 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related FAM91_C PF14648.6 KEG08816.1 - 0.45 9.3 2.6 0.71 8.6 2.6 1.3 1 0 0 1 1 1 0 FAM91 C-terminus Cwf_Cwc_15 PF04889.12 KEG08816.1 - 1.1 9.0 15.2 2.3 7.9 0.2 2.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RabGAP-TBC PF00566.18 KEG08817.1 - 3.4e-33 115.1 0.0 4.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pex24p PF06398.11 KEG08817.1 - 6.2e-10 38.6 3.6 6.2e-10 38.6 3.6 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Complex1_LYR_1 PF13232.6 KEG08817.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like PIF1 PF05970.14 KEG08818.1 - 6.3e-46 157.2 0.1 1.4e-38 133.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KEG08818.1 - 3.9e-18 65.9 0.1 8.4e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KEG08818.1 - 1.2e-10 40.0 0.6 5.3e-07 28.0 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.6 KEG08818.1 - 7.2e-10 39.4 0.0 2.9e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG08818.1 - 2e-05 25.0 0.5 6.4e-05 23.4 0.5 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEG08818.1 - 0.00011 22.2 0.1 0.0004 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG08818.1 - 0.00034 20.9 0.0 0.0009 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEG08818.1 - 0.00094 18.7 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KEG08818.1 - 0.00098 18.9 0.0 0.0029 17.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KEG08818.1 - 0.0087 15.8 0.1 0.11 12.2 0.1 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KEG08818.1 - 0.01 14.9 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KEG08818.1 - 0.012 15.3 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KEG08818.1 - 0.019 14.8 0.1 0.9 9.3 0.0 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase AFG1_ATPase PF03969.16 KEG08818.1 - 0.023 13.6 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.9 KEG08818.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KEG08818.1 - 0.024 15.1 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KEG08818.1 - 0.028 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KEG08818.1 - 0.049 13.6 0.1 0.52 10.2 0.2 2.2 2 0 0 2 2 2 0 NTPase Helicase_RecD PF05127.14 KEG08818.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.6 KEG08818.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KEG08818.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KEG08818.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KEG08818.1 - 0.11 11.7 0.0 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KEG08818.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KEG08818.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KEG08818.1 - 0.17 11.7 0.0 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rotamase PF00639.21 KEG08819.1 - 2.2e-21 76.6 0.0 2.5e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KEG08819.1 - 1.1e-17 64.6 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KEG08819.1 - 3.8e-05 24.5 0.0 4.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Exonuc_VII_S PF02609.16 KEG08819.1 - 0.00036 20.5 0.1 0.0025 17.9 0.1 2.0 2 0 0 2 2 2 1 Exonuclease VII small subunit BRE1 PF08647.11 KEG08820.1 - 0.0011 19.0 13.2 0.0011 19.0 13.2 6.1 5 2 2 7 7 7 1 BRE1 E3 ubiquitin ligase Meth_synt_1 PF08267.12 KEG08820.1 - 0.0073 15.8 4.4 0.84 9.1 0.1 2.5 1 1 1 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DUF971 PF06155.12 KEG08820.1 - 0.042 14.5 0.6 20 5.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF971) Methyltransf_31 PF13847.6 KEG08822.1 - 1.3e-05 25.0 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG08822.1 - 0.00036 21.2 0.4 0.0011 19.7 0.2 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG08822.1 - 0.0008 20.1 0.0 0.0011 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG08822.1 - 0.0098 16.5 0.7 0.028 15.0 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEG08822.1 - 0.033 14.2 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PTPlike_phytase PF14566.6 KEG08823.1 - 3.7e-111 368.2 2.4 4.2e-44 150.4 0.0 3.7 3 0 0 3 3 3 3 Inositol hexakisphosphate LPP PF04728.13 KEG08823.1 - 0.44 11.0 3.2 12 6.4 0.8 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DHHC PF01529.20 KEG08824.1 - 2.6e-30 105.3 9.8 6.6e-30 104.0 9.8 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-ribbon_3 PF13248.6 KEG08824.1 - 0.043 13.2 0.9 0.088 12.2 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KEG08824.1 - 0.31 11.1 8.6 0.46 10.5 8.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon DUF5381 PF17353.2 KEG08824.1 - 2.4 7.9 4.1 3.6 7.3 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5381) DHHC PF01529.20 KEG08825.1 - 1.4e-32 112.6 10.0 1.4e-32 112.6 10.0 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Carla_C4 PF01623.17 KEG08826.1 - 0.095 12.7 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein SLC35F PF06027.12 KEG08828.1 - 3e-49 168.2 10.2 4.3e-44 151.2 2.6 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 KEG08828.1 - 1.2e-09 37.6 3.7 1.2e-09 37.6 3.7 1.4 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KEG08828.1 - 0.00043 20.5 17.3 0.021 15.0 6.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 KEG08828.1 - 0.015 14.4 1.7 0.026 13.7 1.3 1.6 1 1 0 1 1 1 0 Magnesium transporter NIPA PUNUT PF16913.5 KEG08828.1 - 0.12 11.5 9.4 0.023 13.9 3.1 2.1 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport RAMP PF04901.13 KEG08830.1 - 0.031 14.3 0.2 0.097 12.7 0.2 1.9 1 1 0 1 1 1 0 Receptor activity modifying family EVI2A PF05399.11 KEG08830.1 - 0.085 12.4 0.3 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Tad PF13400.6 KEG08830.1 - 2.4 8.5 8.2 7.3 7.0 0.8 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like RNA_pol_Rpb1_5 PF04998.17 KEG08833.1 - 3.3e-08 33.3 0.0 4.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 FWWh PF14922.6 KEG08833.1 - 0.036 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Peptidase_M8 PF01457.16 KEG08835.1 - 2e-138 462.4 1.1 2.4e-138 462.1 1.1 1.0 1 0 0 1 1 1 1 Leishmanolysin CENP-R PF06729.12 KEG08836.1 - 0.065 13.2 3.9 0.19 11.7 3.9 1.7 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF423 PF04241.15 KEG08837.1 - 2e-15 56.8 3.3 2.8e-15 56.3 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) zf-HC2 PF13490.6 KEG08838.1 - 0.008 16.4 1.6 2.5 8.4 0.5 2.5 2 0 0 2 2 2 2 Putative zinc-finger TolA_bind_tri PF16331.5 KEG08840.1 - 0.0039 17.2 0.4 0.0039 17.2 0.4 6.5 5 3 2 8 8 8 1 TolA binding protein trimerisation Ran-binding PF05508.11 KEG08840.1 - 0.21 10.6 3.8 0.59 9.1 3.8 1.8 1 1 0 1 1 1 0 RanGTP-binding protein Fez1 PF06818.15 KEG08840.1 - 2.1 8.8 42.1 0.27 11.7 7.0 3.4 1 1 2 3 3 3 0 Fez1 Kinesin PF00225.23 KEG08841.1 - 1.7e-95 319.7 0.1 2.7e-94 315.8 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08841.1 - 1.7e-19 70.2 1.0 3.9e-14 52.8 0.0 3.4 3 0 0 3 3 3 2 Microtubule binding Kinesin_assoc PF16183.5 KEG08841.1 - 0.0039 17.4 0.3 0.0039 17.4 0.3 5.8 3 2 2 5 5 5 1 Kinesin-associated PEGA PF08308.11 KEG08841.1 - 0.026 14.4 0.8 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 PEGA domain Pox_A_type_inc PF04508.12 KEG08841.1 - 0.35 10.8 3.4 2.4 8.2 2.4 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PhageMin_Tail PF10145.9 KEG08841.1 - 0.54 10.1 11.0 0.079 12.8 4.6 2.8 2 0 0 2 2 2 0 Phage-related minor tail protein Ldh_1_N PF00056.23 KEG08842.1 - 1.7e-36 125.4 0.1 3.3e-36 124.5 0.1 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEG08842.1 - 2.4e-34 118.7 0.0 3.6e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KEG08842.1 - 0.16 10.9 0.0 0.58 9.1 0.0 1.8 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_23 PF13489.6 KEG08843.1 - 1.2e-09 38.2 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG08843.1 - 1.6e-09 38.3 0.0 3.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG08843.1 - 3.8e-09 37.2 0.0 9.4e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG08843.1 - 3.4e-08 34.1 0.0 6.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG08843.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KEG08843.1 - 0.034 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Ank_2 PF12796.7 KEG08844.1 - 3.6e-17 62.7 0.4 1.2e-05 25.8 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG08844.1 - 2e-12 47.1 4.0 0.0024 18.1 0.1 7.6 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KEG08844.1 - 6.1e-11 42.3 5.4 0.61 10.6 0.1 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KEG08844.1 - 5.9e-10 39.5 0.2 0.36 11.5 0.0 6.5 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG08844.1 - 1.8e-07 30.9 2.9 3.2 8.6 0.0 7.5 8 0 0 8 8 8 2 Ankyrin repeat Sel1 PF08238.12 KEG08845.1 - 2e-18 66.4 28.0 0.00016 22.2 0.1 8.1 8 0 0 8 8 8 6 Sel1 repeat DUF2722 PF10846.8 KEG08845.1 - 1.6 7.6 7.6 2.4 7.0 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TPR_7 PF13176.6 KEG08845.1 - 2.5 8.3 10.3 9.2 6.6 0.2 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat ETF_QO PF05187.13 KEG08846.1 - 1.9e-41 140.4 0.2 3.3e-41 139.6 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KEG08846.1 - 1.7e-07 31.1 2.1 0.00014 21.5 1.5 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEG08846.1 - 8e-07 28.6 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG08846.1 - 1.5e-06 28.4 0.1 4.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEG08846.1 - 1e-05 24.4 0.3 0.00018 20.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KEG08846.1 - 4.7e-05 22.7 1.2 0.00033 19.9 2.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KEG08846.1 - 6.9e-05 22.1 0.2 0.0001 21.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KEG08846.1 - 0.00026 20.5 0.1 0.00042 19.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEG08846.1 - 0.00029 20.9 0.2 0.00063 19.8 0.2 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KEG08846.1 - 0.0023 17.2 0.2 0.0042 16.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KEG08846.1 - 0.0042 16.4 0.3 0.0063 15.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEG08846.1 - 0.0049 16.2 0.1 0.018 14.3 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEG08846.1 - 0.013 16.1 0.1 0.44 11.1 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEG08846.1 - 0.014 14.5 0.5 0.023 13.8 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KEG08846.1 - 0.022 13.7 0.2 0.035 12.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KEG08846.1 - 0.17 11.2 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_2 PF12797.7 KEG08846.1 - 9.3 6.6 5.9 0.9 9.8 0.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain NPL PF17800.1 KEG08847.1 - 4.1e-17 62.7 0.0 4.1e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Nucleoplasmin-like domain Sin_N PF04801.13 KEG08847.1 - 0.0093 15.2 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Coilin_N PF15862.5 KEG08847.1 - 0.35 10.7 5.2 0.55 10.0 5.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 KEG08847.1 - 4.4 5.5 7.8 4.9 5.3 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4200 PF13863.6 KEG08849.1 - 0.0091 16.4 9.5 0.0091 16.4 9.5 4.6 4 2 0 4 4 4 1 Domain of unknown function (DUF4200) Gasdermin_C PF17708.1 KEG08849.1 - 0.011 15.9 0.7 0.011 15.9 0.7 2.2 3 0 0 3 3 3 0 Gasdermin PUB domain DUF4972 PF16342.5 KEG08849.1 - 0.038 13.7 3.2 0.29 10.8 0.1 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4972) UIM PF02809.20 KEG08849.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin interaction motif Fib_alpha PF08702.10 KEG08849.1 - 0.31 11.2 17.3 0.33 11.1 0.1 4.0 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Mt_ATP-synt_D PF05873.12 KEG08849.1 - 0.4 10.5 13.9 2.4 8.0 0.2 4.3 3 1 2 5 5 5 0 ATP synthase D chain, mitochondrial (ATP5H) TMF_DNA_bd PF12329.8 KEG08849.1 - 0.44 10.6 28.6 5.8 7.0 0.1 6.4 5 1 0 6 6 6 0 TATA element modulatory factor 1 DNA binding TACC_C PF05010.14 KEG08849.1 - 4.4 7.0 27.1 0.35 10.6 9.8 3.8 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 KEG08849.1 - 4.5 8.0 24.4 8.7 7.0 0.3 5.5 4 1 1 5 5 5 0 SlyX DASH_Spc19 PF08287.11 KEG08849.1 - 9.9 6.0 30.3 0.54 10.1 6.2 3.9 3 1 0 3 3 3 0 Spc19 DUF4407 PF14362.6 KEG08850.1 - 0.00065 19.1 0.6 0.00076 18.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 KEG08850.1 - 0.01 15.5 0.6 0.013 15.2 0.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 KEG08850.1 - 0.015 14.2 1.8 0.021 13.7 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Metal_resist PF13801.6 KEG08850.1 - 0.027 14.7 1.0 0.04 14.1 0.5 1.6 1 1 1 2 2 2 0 Heavy-metal resistance Gon7 PF08738.10 KEG08850.1 - 0.16 12.1 1.1 0.26 11.4 0.6 1.7 1 1 1 2 2 2 0 Gon7 family CLZ PF16526.5 KEG08850.1 - 0.2 12.0 3.9 0.17 12.3 1.3 2.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4200 PF13863.6 KEG08850.1 - 0.65 10.4 6.2 28 5.1 6.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF919 PF06034.11 KEG08850.1 - 0.68 9.8 0.1 0.68 9.8 0.1 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) APG6_N PF17675.1 KEG08850.1 - 3.4 8.2 8.2 11 6.6 8.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Vac_Fusion PF02346.16 KEG08851.1 - 0.0032 17.1 5.6 0.82 9.3 0.1 4.2 3 0 0 3 3 3 2 Chordopoxvirus multifunctional envelope protein A27 HMG_box PF00505.19 KEG08851.1 - 0.0087 16.4 1.2 0.0087 16.4 1.2 5.1 4 1 1 5 5 5 1 HMG (high mobility group) box LPD13 PF18825.1 KEG08851.1 - 0.036 13.8 4.9 0.11 12.2 2.7 2.8 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 13 DUF948 PF06103.11 KEG08851.1 - 6.4 7.1 17.4 0.99 9.7 0.9 4.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) SUIM_assoc PF16619.5 KEG08852.1 - 0.0095 16.0 1.5 0.0095 16.0 1.5 3.5 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 KEG08852.1 - 0.15 12.0 29.1 0.61 10.0 15.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L1 PF00687.21 KEG08853.1 - 5.3e-10 39.4 0.0 6.1e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PIF1 PF05970.14 KEG08854.1 - 3.2e-40 138.4 0.0 3e-36 125.4 0.0 2.6 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KEG08854.1 - 2.5e-18 66.5 0.0 7.5e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG08854.1 - 1.6e-08 35.0 0.0 3.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KEG08854.1 - 3.6e-07 30.2 0.8 0.033 13.9 0.3 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KEG08854.1 - 7.9e-06 25.6 0.2 1.9e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KEG08854.1 - 0.00032 20.6 0.2 0.25 11.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEG08854.1 - 0.00034 21.1 0.5 0.011 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KEG08854.1 - 0.0014 17.6 0.3 0.0025 16.8 0.3 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.21 KEG08854.1 - 0.0016 18.0 0.3 0.0026 17.3 0.3 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KEG08854.1 - 0.0034 17.2 0.1 0.019 14.7 0.1 1.9 1 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KEG08854.1 - 0.0053 16.0 0.1 0.035 13.4 0.3 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KEG08854.1 - 0.0068 16.3 0.2 2.7 7.9 0.1 2.5 1 1 1 2 2 2 2 NTPase AAA_24 PF13479.6 KEG08854.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KEG08854.1 - 0.049 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KEG08854.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Herpes_Helicase PF02689.14 KEG08854.1 - 0.1 10.5 0.7 2 6.3 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_22 PF13401.6 KEG08854.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEG08854.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Cnn_1N PF07989.11 KEG08855.1 - 0.055 13.6 1.8 0.11 12.7 0.5 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 IMPDH PF00478.25 KEG08857.1 - 3.2e-125 417.7 5.1 3.6e-125 417.5 5.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KEG08857.1 - 4.7e-10 39.8 0.0 0.00034 21.0 0.0 2.8 1 1 1 2 2 2 2 CBS domain FMN_dh PF01070.18 KEG08857.1 - 4.8e-09 35.7 0.8 9.8e-09 34.7 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KEG08857.1 - 4e-07 29.7 4.7 0.00014 21.4 2.8 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KEG08857.1 - 0.00038 20.0 0.4 0.039 13.4 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein Aldolase PF01081.19 KEG08857.1 - 0.01 15.3 0.4 0.066 12.6 0.2 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase Glu_synthase PF01645.17 KEG08857.1 - 0.018 14.2 2.4 0.033 13.3 2.4 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.14 KEG08857.1 - 0.033 13.4 0.2 0.08 12.1 0.2 1.7 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ELMO_CED12 PF04727.13 KEG08858.1 - 9e-28 97.6 0.0 1.2e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_M41 PF01434.18 KEG08860.1 - 1.3e-39 136.0 0.1 2e-39 135.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEG08860.1 - 4.5e-39 133.9 0.0 1.1e-38 132.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG08860.1 - 1.9e-05 24.4 0.2 5.3e-05 22.9 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KEG08860.1 - 9.4e-05 22.7 1.6 0.0054 17.0 0.1 3.6 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG08860.1 - 0.0014 19.0 4.7 0.01 16.3 0.3 3.5 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.12 KEG08860.1 - 0.0022 17.3 0.3 0.085 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 KEG08860.1 - 0.0024 17.9 0.0 0.0085 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG08860.1 - 0.0081 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KEG08860.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Peptidase_M50B PF13398.6 KEG08860.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like IstB_IS21 PF01695.17 KEG08860.1 - 0.033 13.9 0.1 0.093 12.5 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TetR_C_36 PF18598.1 KEG08860.1 - 0.042 13.8 0.5 0.55 10.2 0.0 2.7 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain DUF2075 PF09848.9 KEG08860.1 - 0.052 12.8 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KEG08860.1 - 0.089 12.6 0.1 1 9.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KEG08860.1 - 0.1 12.7 0.0 0.66 10.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KEG08860.1 - 0.48 10.0 4.5 0.6 9.6 0.4 2.8 2 1 1 3 3 3 0 AAA domain Pkinase PF00069.25 KEG08861.1 - 6.4e-36 124.1 0.0 7.7e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08861.1 - 3.1e-18 66.0 0.0 3.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08861.1 - 3.3e-08 33.2 0.0 4.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KEG08861.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KEG08861.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KEG08861.1 - 0.014 14.7 0.7 0.021 14.2 0.1 1.6 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG08861.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KEG08861.1 - 0.038 13.9 0.7 0.21 11.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nup88 PF10168.9 KEG08861.1 - 0.13 10.1 0.2 0.17 9.6 0.2 1.1 1 0 0 1 1 1 0 Nuclear pore component BTB_2 PF02214.22 KEG08862.1 - 1.6e-11 44.4 0.0 3.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KEG08862.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Nodulin-like PF06813.13 KEG08866.1 - 6e-17 62.0 21.2 8.5e-16 58.2 21.2 2.5 1 1 0 1 1 1 1 Nodulin-like PspB PF06667.12 KEG08866.1 - 0.38 10.8 2.5 5.2 7.2 0.0 2.9 2 0 0 2 2 2 0 Phage shock protein B Asn_synthase PF00733.21 KEG08867.1 - 1.1e-11 45.0 0.4 0.00081 19.1 0.3 3.5 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KEG08867.1 - 0.089 12.7 0.1 0.43 10.5 0.0 2.2 2 1 0 2 2 2 0 Glutamine amidotransferase domain Ank_2 PF12796.7 KEG08869.1 - 6.5e-08 33.1 0.1 1.7e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG08869.1 - 9.8e-08 32.4 0.0 2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 KEG08869.1 - 7.8e-05 22.9 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_3 PF13606.6 KEG08869.1 - 0.00033 20.8 0.1 0.12 13.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KEG08869.1 - 0.011 16.0 0.1 0.054 13.8 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) NMT PF01233.19 KEG08869.1 - 0.014 15.3 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_10 PF13673.7 KEG08869.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEG08869.1 - 0.035 14.2 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEG08869.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1_like PF12832.7 KEG08871.1 - 5.4e-07 28.8 1.5 6.7e-07 28.5 1.5 1.1 1 0 0 1 1 1 1 MFS_1 like family Pardaxin PF07425.11 KEG08871.1 - 0.22 11.2 1.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Pardaxin Cwf_Cwc_15 PF04889.12 KEG08872.1 - 5.8e-09 36.0 6.3 8.2e-09 35.6 5.8 1.5 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein ANAPC_CDC26 PF10471.9 KEG08872.1 - 0.02 15.7 1.7 0.02 15.7 1.7 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 CDC45 PF02724.14 KEG08872.1 - 0.31 9.3 6.8 0.42 8.9 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC1 PF03109.16 KEG08873.1 - 2.7e-27 95.3 0.0 7.5e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KEG08873.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KEG08873.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 KEG08873.1 - 0.24 11.3 5.4 0.27 11.1 0.3 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family MFS_1_like PF12832.7 KEG08874.1 - 3e-55 187.7 22.6 7.5e-55 186.3 22.6 1.6 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KEG08874.1 - 3.4e-19 69.0 44.7 4.8e-12 45.5 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KEG08874.1 - 7.6e-11 41.6 20.7 1.3e-10 40.9 20.7 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter DGF-1_5 PF11038.8 KEG08875.1 - 2.1e-119 397.9 13.0 3.1e-119 397.4 13.0 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DGF-1_4 PF11024.8 KEG08875.1 - 0.0036 18.1 0.3 0.0095 16.7 0.3 1.7 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Snf7 PF03357.21 KEG08877.1 - 3.9e-29 101.5 25.8 3.9e-29 101.5 25.8 1.5 2 0 0 2 2 2 1 Snf7 DUF3502 PF12010.8 KEG08877.1 - 4.3e-06 27.4 6.1 6.7e-06 26.8 5.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3502) MutS_II PF05188.17 KEG08877.1 - 0.12 12.6 2.4 0.17 12.2 1.1 1.8 1 1 1 2 2 2 0 MutS domain II XhlA PF10779.9 KEG08877.1 - 5.9 7.2 8.7 2.3 8.5 0.2 2.8 2 1 0 2 2 2 0 Haemolysin XhlA HGTP_anticodon PF03129.20 KEG08878.1 - 3.3e-16 59.2 0.0 8.6e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEG08878.1 - 2.6e-08 34.0 0.0 9.6e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3053 PF11254.8 KEG08880.1 - 0.016 14.8 0.6 0.024 14.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) CENP-F_leu_zip PF10473.9 KEG08880.1 - 0.42 10.6 7.6 0.35 10.9 2.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.6 KEG08881.1 - 1.6e-17 63.1 26.8 5.1e-12 45.5 11.4 4.9 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG08881.1 - 9.6e-08 31.8 34.2 3.8e-05 23.5 10.4 4.1 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 VHS PF00790.19 KEG08883.1 - 1.4e-12 47.6 0.0 3.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 VHS domain zf-LYAR PF08790.11 KEG08883.1 - 0.03 14.2 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger VCPO_N PF17897.1 KEG08883.1 - 0.27 11.0 3.2 4.2 7.1 0.2 2.4 1 1 1 2 2 2 0 Vanadium chloroperoxidase N-terminal domain Spt20 PF12090.8 KEG08883.1 - 2.2 7.8 13.1 0.55 9.8 6.7 2.5 2 0 0 2 2 2 0 Spt20 family DDE_Tnp_1_2 PF13586.6 KEG08883.1 - 4.9 7.6 6.6 57 4.2 0.0 3.8 4 0 0 4 4 4 0 Transposase DDE domain TFIIA PF03153.13 KEG08883.1 - 5.3 6.9 28.2 4.5 7.2 23.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ZapB PF06005.12 KEG08885.1 - 0.084 13.3 10.0 15 6.1 10.0 2.3 1 1 0 1 1 1 0 Cell division protein ZapB DUF1796 PF08795.10 KEG08885.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) TolA_bind_tri PF16331.5 KEG08885.1 - 2.5 8.2 13.5 1 9.5 2.4 2.8 2 1 1 3 3 3 0 TolA binding protein trimerisation Ntox1 PF15500.6 KEG08885.1 - 3.6 8.0 7.3 4.4 7.7 2.5 2.6 1 1 2 3 3 3 0 Putative RNase-like toxin, toxin_1 Ribosomal_S2 PF00318.20 KEG08886.1 - 1.7e-27 96.1 0.2 1.6e-14 53.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KEG08886.1 - 0.0021 19.4 0.2 0.0039 18.5 0.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus HU-CCDC81_euk_1 PF14908.6 KEG08887.1 - 1e-14 54.4 0.0 1.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 KEG08887.1 - 4.1e-12 46.1 0.0 1.3e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HTH_38 PF13936.6 KEG08887.1 - 0.11 12.3 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PUF PF00806.19 KEG08888.1 - 1.1e-10 40.5 0.6 0.0032 17.1 0.0 4.3 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat DDHD PF02862.17 KEG08888.1 - 0.054 13.6 6.5 1.4 9.0 3.3 2.5 2 1 0 2 2 2 0 DDHD domain SUIM_assoc PF16619.5 KEG08888.1 - 0.071 13.2 0.1 0.071 13.2 0.1 5.3 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 KEG08888.1 - 0.34 11.3 10.5 3.9 7.9 2.9 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Zip PF02535.22 KEG08888.1 - 0.5 9.5 8.6 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter FAM76 PF16046.5 KEG08888.1 - 1.4 8.2 9.6 5 6.4 3.5 2.2 2 0 0 2 2 2 0 FAM76 protein Ctr PF04145.15 KEG08888.1 - 2.1 9.0 3.6 35 5.0 0.0 2.5 2 0 0 2 2 2 0 Ctr copper transporter family FAM176 PF14851.6 KEG08888.1 - 3.6 7.2 7.3 0.6 9.8 0.3 2.3 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 KEG08888.1 - 3.6 6.2 10.4 3.1 6.5 0.9 2.2 2 0 0 2 2 2 0 Presenilin Gti1_Pac2 PF09729.9 KEG08888.1 - 4.1 7.4 7.2 16 5.6 0.2 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Pkinase PF00069.25 KEG08889.1 - 4.2e-57 193.5 0.0 5.3e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08889.1 - 1.1e-25 90.4 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08889.1 - 6.2e-06 25.7 0.0 1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KEG08889.1 - 5.2e-05 23.3 0.2 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KEG08889.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KEG08889.1 - 0.051 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PSP1 PF04468.12 KEG08890.1 - 3e-15 56.3 2.3 4.3e-15 55.8 2.3 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PAP2_C PF14360.6 KEG08891.1 - 2.8e-19 69.4 10.7 2.8e-19 69.4 10.7 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 KEG08891.1 - 1 9.2 8.3 0.41 10.4 4.7 2.1 2 0 0 2 2 2 0 PAP2 superfamily Mucin PF01456.17 KEG08892.1 - 0.0001 22.3 7.0 0.00013 22.0 7.0 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3169 PF11368.8 KEG08892.1 - 0.0017 17.9 0.0 0.0019 17.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Shisa PF13908.6 KEG08892.1 - 0.0032 17.8 0.5 0.0032 17.8 0.5 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SSP160 PF06933.11 KEG08892.1 - 0.0098 14.1 6.7 0.0091 14.3 6.7 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF4834 PF16118.5 KEG08892.1 - 0.012 16.6 0.1 0.014 16.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) B277 PF17623.2 KEG08892.1 - 0.038 13.1 1.6 0.043 12.9 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function Ion_trans PF00520.31 KEG08892.1 - 0.091 12.0 0.0 0.094 11.9 0.0 1.0 1 0 0 1 1 1 0 Ion transport protein Dicty_REP PF05086.12 KEG08892.1 - 0.16 9.9 7.0 0.18 9.8 7.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sex_peptide PF08138.11 KEG08893.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Sex peptide (SP) family Rbx_binding PF18113.1 KEG08896.1 - 0.12 12.1 0.3 0.37 10.6 0.3 1.9 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain Orthopox_A5L PF06193.11 KEG08899.1 - 0.051 13.0 0.5 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF5522 PF17653.1 KEG08899.1 - 4.3 7.4 7.0 33 4.5 0.8 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5522) Anp1 PF03452.14 KEG08899.1 - 5.3 6.4 5.8 12 5.2 5.8 1.5 1 0 0 1 1 1 0 Anp1 TERB2 PF15101.6 KEG08900.1 - 0.046 13.8 0.7 0.1 12.7 0.2 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Herpes_capsid PF06112.11 KEG08900.1 - 0.46 10.5 6.3 0.93 9.5 6.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NTP_transf_2 PF01909.23 KEG08901.1 - 5.6e-06 26.6 0.0 1.8e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEG08901.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 KEG08901.1 - 0.035 13.9 0.1 1.4 8.7 0.0 2.4 2 1 1 3 3 3 0 Nrap protein PAP/OAS-like domain FG-GAP PF01839.23 KEG08902.1 - 0.078 13.1 2.4 0.17 12.1 0.1 2.7 3 0 0 3 3 3 0 FG-GAP repeat KCNQ2_u3 PF16642.5 KEG08902.1 - 2.2 9.3 5.1 0.68 11.0 1.5 2.0 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 ATG16 PF08614.11 KEG08903.1 - 8.3 6.6 15.3 3.1 8.0 0.1 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Kinesin PF00225.23 KEG08904.1 - 2.8e-53 181.0 0.0 3.3e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08904.1 - 1.9e-22 79.8 0.0 4.1e-21 75.5 0.0 2.2 1 1 0 1 1 1 1 Microtubule binding T2SSE PF00437.20 KEG08904.1 - 0.011 14.8 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 KEG08904.1 - 0.045 14.1 0.0 0.097 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Bac_DnaA PF00308.18 KEG08904.1 - 0.056 13.3 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 KEG08904.1 - 0.16 12.3 0.4 0.65 10.3 0.2 2.0 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 KEG08904.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Kinesin PF00225.23 KEG08905.1 - 2.5e-19 69.4 0.2 7.6e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF1192 PF06698.11 KEG08905.1 - 7.9e-05 22.6 0.5 0.028 14.5 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) Rab_bind PF16704.5 KEG08905.1 - 0.008 16.2 4.6 0.43 10.6 0.1 3.5 2 1 1 3 3 3 1 Rab binding domain AHH PF14412.6 KEG08905.1 - 0.034 14.2 2.4 1.2 9.2 0.1 2.9 3 1 0 3 3 3 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Cep57_CLD_2 PF14197.6 KEG08905.1 - 0.034 14.2 0.2 0.034 14.2 0.2 4.1 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF641 PF04859.12 KEG08905.1 - 1.4 9.3 12.1 2.9 8.2 0.1 4.3 4 1 1 5 5 5 0 Plant protein of unknown function (DUF641) zf-MYND PF01753.18 KEG08906.1 - 2.4e-11 43.5 7.0 2.4e-11 43.5 7.0 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KEG08906.1 - 9.9e-05 22.6 3.7 9.9e-05 22.6 3.7 2.7 2 1 1 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding Sld5 PF05916.11 KEG08907.1 - 2.5e-07 31.1 0.0 3.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Yop-YscD_ppl PF16693.5 KEG08908.1 - 0.019 14.4 0.3 0.026 13.9 0.3 1.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain Iron_permease PF04120.12 KEG08908.1 - 0.54 10.0 2.1 1 9.1 2.1 1.5 1 0 0 1 1 1 0 Low affinity iron permease Amelotin PF15757.5 KEG08910.1 - 0.2 11.2 1.7 0.33 10.5 0.3 1.9 2 0 0 2 2 2 0 Amelotin PLAC8 PF04749.17 KEG08911.1 - 2e-09 38.3 22.4 2e-09 38.3 22.4 1.4 2 0 0 2 2 2 1 PLAC8 family PLAC8 PF04749.17 KEG08912.1 - 4.1e-09 37.3 25.5 4.1e-09 37.3 25.5 1.4 2 0 0 2 2 2 1 PLAC8 family Cpn60_TCP1 PF00118.24 KEG08913.1 - 0.00026 19.8 0.1 0.00028 19.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KEG08914.1 - 3.9e-68 230.3 10.8 7.6e-68 229.3 10.8 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MutS_V PF00488.21 KEG08915.1 - 4e-52 177.0 0.0 8.1e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KEG08915.1 - 1.2e-33 115.7 0.0 2.4e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KEG08915.1 - 5.7e-25 88.7 0.0 1.2e-24 87.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KEG08915.1 - 2.1e-05 24.8 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV ABC_tran PF00005.27 KEG08915.1 - 0.0096 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KEG08915.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KEG08915.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PLAC8 PF04749.17 KEG08916.1 - 8.6e-08 33.1 15.9 1.1e-07 32.7 15.9 1.2 1 0 0 1 1 1 1 PLAC8 family LicD PF04991.13 KEG08917.1 - 9.9e-10 38.9 0.2 4.2e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 LicD family Amidase PF01425.21 KEG08918.1 - 1.1 8.2 2.8 2.5 7.0 2.8 1.5 1 0 0 1 1 1 0 Amidase tRNA-synt_1c PF00749.21 KEG08918.1 - 1.3 7.9 9.0 0.49 9.2 0.5 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Aldo_ket_red PF00248.21 KEG08919.1 - 0.009 15.2 0.0 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 Aldo/keto reductase family SLC3A2_N PF16028.5 KEG08920.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF1462 PF07315.11 KEG08920.1 - 0.12 12.7 0.1 0.35 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Phage_gp53 PF11246.8 KEG08920.1 - 0.13 11.9 0.4 0.22 11.2 0.4 1.2 1 0 0 1 1 1 0 Base plate wedge protein 53 Fer2 PF00111.27 KEG08922.1 - 1.6e-13 50.4 0.3 2.4e-13 49.8 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 KEG08922.1 - 2.1 8.5 5.4 1.4 9.0 1.4 2.7 3 1 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.22 KEG08923.1 - 6.8e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 KEG08924.1 - 3.8e-09 35.9 0.1 8.7e-09 34.7 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF1455 PF07306.11 KEG08924.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) TMF_DNA_bd PF12329.8 KEG08925.1 - 0.026 14.5 1.4 0.064 13.3 1.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Zn_ribbon_recom PF13408.6 KEG08926.1 - 0.027 15.0 0.2 0.053 14.0 0.2 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain HrpB7 PF09486.10 KEG08926.1 - 0.83 10.0 4.0 0.27 11.6 0.6 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DnaJ PF00226.31 KEG08927.1 - 9.5e-08 32.1 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Helicase_C PF00271.31 KEG08928.1 - 1.5e-08 34.9 0.0 4.9e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG08928.1 - 4.8e-07 29.7 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 KEG08928.1 - 0.011 16.0 0.0 0.011 16.0 0.0 2.5 2 1 0 2 2 2 0 Helicase associated domain (HA2) T2SSE PF00437.20 KEG08928.1 - 0.034 13.2 0.2 0.081 12.0 0.2 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KEG08928.1 - 0.083 13.2 0.9 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hid1 PF12722.7 KEG08928.1 - 6.6 4.7 7.2 9.7 4.2 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cupin_4 PF08007.12 KEG08929.1 - 6e-42 144.2 0.6 1.4e-41 143.1 0.5 1.6 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KEG08929.1 - 1.3e-06 28.4 0.0 3.4e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain 2OG-FeII_Oxy_2 PF13532.6 KEG08931.1 - 6.2e-07 29.8 0.0 7.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.13 KEG08932.1 - 2.3e-05 24.7 0.0 2.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF179 PF02622.15 KEG08933.1 - 6.4e-07 29.5 0.0 5.7e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized ACR, COG1678 WD40 PF00400.32 KEG08934.1 - 1.2e-47 158.9 21.6 1.7e-09 38.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG08934.1 - 3.7e-15 56.0 1.3 0.039 14.2 0.0 5.5 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 KEG08934.1 - 9.7e-06 24.9 0.1 0.11 11.5 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) PD40 PF07676.12 KEG08934.1 - 0.00021 21.1 0.4 3.1 7.9 0.1 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KEG08934.1 - 0.00024 19.9 7.0 0.2 10.3 0.2 4.4 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEG08934.1 - 0.00037 19.6 0.1 1.1 8.2 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KEG08934.1 - 0.041 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain WD40_like PF17005.5 KEG08934.1 - 0.17 11.2 0.0 2.2 7.5 0.0 2.2 2 1 1 3 3 3 0 WD40-like domain AAA PF00004.29 KEG08935.1 - 3.5e-10 40.4 0.0 4.3e-08 33.6 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG08935.1 - 0.2 12.0 2.4 0.24 11.8 0.1 2.2 3 1 1 4 4 4 0 AAA ATPase domain GCP_N_terminal PF17681.1 KEG08936.1 - 4.5e-45 154.6 2.3 1.1e-44 153.3 0.0 2.4 2 1 0 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KEG08936.1 - 1.7e-42 146.0 10.4 2.8e-42 145.3 10.4 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal LAL_C2 PF18603.1 KEG08937.1 - 0.0025 17.9 2.6 1.8 8.8 0.3 3.3 1 1 1 2 2 2 2 L-amino acid ligase C-terminal domain 2 VWA_2 PF13519.6 KEG08937.1 - 0.021 15.4 1.8 0.021 15.4 1.8 2.9 1 1 2 3 3 3 0 von Willebrand factor type A domain GW PF13457.6 KEG08937.1 - 0.12 13.0 1.2 0.92 10.2 0.3 2.7 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain Mce4_CUP1 PF11887.8 KEG08937.1 - 0.33 10.3 10.3 2.2 7.7 3.5 2.2 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative T3SS_basalb_I PF17001.5 KEG08937.1 - 0.7 10.5 15.8 4 8.1 4.2 3.3 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI PTPlike_phytase PF14566.6 KEG08937.1 - 2.7 8.1 5.7 1.6 8.9 0.7 2.6 1 1 1 2 2 2 0 Inositol hexakisphosphate Mucin PF01456.17 KEG08941.1 - 0.0026 17.7 0.1 0.0036 17.3 0.1 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Pkinase PF00069.25 KEG08944.1 - 1.9e-57 194.7 0.0 2.2e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08944.1 - 1.5e-30 106.4 0.0 2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08944.1 - 8.6e-05 22.0 0.0 0.00022 20.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG08944.1 - 0.0024 16.7 0.0 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG08944.1 - 0.055 13.4 0.0 0.59 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HA2 PF04408.23 KEG08945.1 - 2.3e-16 60.0 0.1 2.3e-16 60.0 0.1 2.4 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEG08945.1 - 5.8e-13 49.2 0.0 2.3e-12 47.3 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG08945.1 - 1.1e-09 38.3 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KEG08945.1 - 6.3e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KEG08945.1 - 6.1e-05 23.3 0.1 0.00025 21.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KEG08945.1 - 0.0095 15.5 0.3 0.52 9.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KEG08945.1 - 0.011 14.9 0.9 0.028 13.5 0.9 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KEG08945.1 - 0.015 15.9 0.1 0.015 15.9 0.1 2.7 1 1 2 3 3 2 0 AAA domain AAA_19 PF13245.6 KEG08945.1 - 0.021 15.2 0.3 0.15 12.3 0.3 2.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KEG08945.1 - 0.049 13.0 0.1 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 KaiC PhoH PF02562.16 KEG08945.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KEG08945.1 - 0.056 13.2 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEG08945.1 - 0.061 13.8 0.1 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 KEG08945.1 - 0.07 12.6 0.0 4.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 KEG08945.1 - 0.079 12.4 0.0 0.77 9.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_14 PF13173.6 KEG08945.1 - 0.14 12.2 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NifU PF01106.17 KEG08946.1 - 6.1e-24 84.0 0.0 1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 KEG08946.1 - 8.8e-13 48.1 0.0 2.3e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal DUF5030 PF16433.5 KEG08946.1 - 0.081 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) eIF-6 PF01912.18 KEG08947.1 - 2.7e-80 268.4 0.2 4e-80 267.9 0.2 1.2 1 0 0 1 1 1 1 eIF-6 family Glyco_trans_1_4 PF13692.6 KEG08947.1 - 0.081 13.4 0.2 2.2 8.7 0.0 2.7 2 1 1 3 3 3 0 Glycosyl transferases group 1 Pkinase PF00069.25 KEG08948.1 - 1.3e-75 254.1 0.0 1.9e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08948.1 - 1.3e-38 132.8 0.0 2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08948.1 - 7.9e-05 22.1 0.1 0.00029 20.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEG08948.1 - 0.0038 16.6 0.6 0.0064 15.9 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEG08948.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family DUF5383 PF17355.2 KEG08949.1 - 0.13 12.7 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) zinc_ribbon_9 PF14369.6 KEG08949.1 - 0.16 12.2 2.8 0.32 11.3 2.8 1.5 1 0 0 1 1 1 0 zinc-ribbon ACC_epsilon PF13822.6 KEG08950.1 - 0.72 10.6 0.2 0.72 10.6 0.2 2.9 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit RIFIN PF02009.16 KEG08953.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.9 2 1 1 3 3 3 0 Rifin DUF4771 PF15995.5 KEG08954.1 - 4.1 7.6 4.9 2.2 8.5 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) Kinesin PF00225.23 KEG08955.1 - 2.5e-86 289.6 0.0 1.9e-83 280.2 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG08955.1 - 3e-16 59.7 0.1 4.4e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding SPATA24 PF15175.6 KEG08955.1 - 0.25 11.2 1.1 0.48 10.3 1.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Wyosine_form PF08608.12 KEG08956.1 - 1e-20 73.8 0.3 1.1e-13 51.3 0.0 2.5 2 0 0 2 2 2 2 Wyosine base formation Radical_SAM PF04055.21 KEG08956.1 - 1.8e-13 51.2 0.0 3.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Prominin PF05478.11 KEG08957.1 - 1.8 6.4 8.8 2.4 6.0 8.8 1.1 1 0 0 1 1 1 0 Prominin DUF3446 PF11928.8 KEG08957.1 - 2.5 8.5 15.5 4.4 7.7 0.3 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain SAC3_GANP PF03399.16 KEG08960.1 - 2.4e-07 30.4 0.5 5.6e-07 29.2 0.5 1.6 1 1 0 1 1 1 1 SAC3/GANP family Sin_N PF04801.13 KEG08960.1 - 3.3 6.8 19.7 1.6 7.8 3.8 2.4 2 0 0 2 2 2 0 Sin-like protein conserved region DUF1772 PF08592.11 KEG08960.1 - 9.1 6.6 11.4 1.4 9.2 0.7 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) DUF3638 PF12340.8 KEG08962.1 - 1.5e-30 106.2 0.1 8.4e-29 100.5 0.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KEG08962.1 - 6e-16 57.5 0.2 1.5e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.18 KEG08962.1 - 0.0003 20.0 25.1 0.001 18.3 3.8 4.0 3 1 0 3 3 3 3 Zn-finger in Ran binding protein and others Actin PF00022.19 KEG08963.1 - 5.2e-97 325.0 0.0 1.6e-96 323.4 0.0 1.6 1 1 0 1 1 1 1 Actin CHCH PF06747.13 KEG08964.1 - 8.7e-07 28.9 1.4 1.7e-06 28.0 1.4 1.5 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KEG08964.1 - 0.0045 17.0 0.6 0.009 16.0 0.6 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KEG08964.1 - 0.0055 16.4 0.9 0.0091 15.7 0.9 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 KEG08964.1 - 0.017 15.5 2.8 0.29 11.5 0.4 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KEG08964.1 - 0.041 13.9 4.5 1 9.4 0.7 2.3 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KEG08964.1 - 0.075 13.3 3.1 0.22 11.9 3.1 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 MTCP1 PF08991.10 KEG08964.1 - 0.16 12.2 3.4 0.33 11.2 3.4 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Presenilin PF01080.17 KEG08965.1 - 8.7 5.0 12.3 5.6 5.6 10.0 1.8 2 0 0 2 2 2 0 Presenilin TMF_TATA_bd PF12325.8 KEG08967.1 - 0.0034 17.6 5.5 0.8 9.9 0.0 3.5 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 KEG08967.1 - 0.014 15.8 0.7 0.051 14.0 0.7 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Cluap1 PF10234.9 KEG08967.1 - 0.016 14.6 2.5 0.035 13.5 2.5 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF2046 PF09755.9 KEG08967.1 - 0.052 12.8 6.4 3.1 6.9 2.8 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Phage_sheath_1 PF04984.14 KEG08967.1 - 0.072 12.9 3.3 0.56 10.0 0.3 2.3 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Cep57_CLD_2 PF14197.6 KEG08967.1 - 0.45 10.6 5.5 28 4.9 0.2 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 KEG08967.1 - 0.88 10.0 12.2 1.4 9.3 5.6 3.2 1 1 0 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 KEG08967.1 - 4.1 7.4 11.3 2.3 8.2 1.2 3.9 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SUIM_assoc PF16619.5 KEG08967.1 - 8.8 6.5 24.9 0.027 14.5 3.7 3.9 4 1 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 COG2 PF06148.11 KEG08967.1 - 9.4 6.3 6.7 19 5.3 0.5 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IPK PF03770.16 KEG08971.1 - 9.3e-43 146.4 0.0 1.9e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase VIR_N PF15912.5 KEG08971.1 - 0.11 12.0 3.3 0.56 9.8 0.8 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Thr_synth_N PF14821.6 KEG08972.1 - 1.5e-11 44.4 0.0 4.1e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KEG08972.1 - 4.5e-10 39.4 0.0 5.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DEAD PF00270.29 KEG08973.1 - 3e-07 30.4 0.1 4e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KEG08973.1 - 0.05 12.4 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 KEG08973.1 - 0.23 11.4 0.0 0.3 11.1 0.0 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KEG08974.1 - 1.4e-18 66.9 47.4 1.8e-09 37.0 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG08974.1 - 7.6e-07 28.3 26.5 0.0015 17.5 6.7 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter AAA PF00004.29 KEG08975.1 - 1.4e-43 148.5 0.0 2.9e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEG08975.1 - 9.1e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEG08975.1 - 3.2e-05 24.4 0.1 0.013 15.9 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KEG08975.1 - 0.00027 21.1 0.0 0.00071 19.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEG08975.1 - 0.00032 21.0 0.0 0.083 13.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.10 KEG08975.1 - 0.00036 20.5 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KEG08975.1 - 0.0019 18.0 0.8 0.005 16.6 0.2 2.1 2 0 0 2 2 1 1 AAA+ lid domain RNA_helicase PF00910.22 KEG08975.1 - 0.0027 18.0 0.0 0.0086 16.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 KEG08975.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEG08975.1 - 0.006 16.6 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEG08975.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEG08975.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KEG08975.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KEG08975.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KEG08975.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KEG08975.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEG08975.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_trans_1_4 PF13692.6 KEG08975.1 - 0.057 13.9 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 AAA_18 PF13238.6 KEG08975.1 - 0.06 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEG08975.1 - 0.08 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEG08975.1 - 0.081 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KEG08975.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KEG08975.1 - 0.23 10.8 0.0 0.5 9.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Myb_DNA-binding PF00249.31 KEG08976.1 - 0.041 14.1 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Kelch_5 PF13854.6 KEG08977.1 - 1.9e-25 88.4 4.0 3.1e-06 27.0 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KEG08977.1 - 4.3e-25 87.5 6.4 1.8e-07 31.3 0.1 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KEG08977.1 - 3.3e-24 84.6 4.2 0.00011 22.1 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG08977.1 - 5.3e-21 74.1 7.4 0.0037 17.5 0.0 6.4 5 1 1 6 6 6 5 Kelch motif DUF4110 PF13422.6 KEG08977.1 - 2.2e-18 66.1 11.4 2.2e-18 66.1 11.4 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 KEG08977.1 - 5e-15 54.8 10.8 0.0071 15.9 0.0 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KEG08977.1 - 2e-10 40.2 9.1 0.68 10.0 0.0 6.5 6 1 0 6 6 6 4 Kelch motif Gag_p30 PF02093.16 KEG08977.1 - 0.038 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Gag P30 core shell protein Pkinase PF00069.25 KEG08979.1 - 5.6e-74 248.8 0.0 7.2e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08979.1 - 3.1e-39 134.8 0.0 4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08979.1 - 1.2e-09 37.9 0.0 3.9e-09 36.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KEG08979.1 - 1.9e-06 27.1 0.2 2.9e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG08979.1 - 0.00076 19.5 0.0 0.051 13.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG08979.1 - 0.0052 16.4 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KEG08979.1 - 0.033 13.8 0.0 0.089 12.4 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KEG08979.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KEG08980.1 - 1.5e-75 254.0 0.0 1.7e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08980.1 - 3.2e-40 138.0 0.0 3.8e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08980.1 - 3.1e-10 39.8 0.0 1.3e-09 37.8 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KEG08980.1 - 0.00027 20.0 0.2 0.00036 19.6 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEG08980.1 - 0.0053 16.1 0.2 0.0098 15.3 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG08980.1 - 0.012 15.6 0.2 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF421 PF04239.12 KEG08980.1 - 0.1 12.3 0.5 0.25 11.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Phosducin PF02114.16 KEG08980.1 - 0.19 10.7 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin Pkinase PF00069.25 KEG08981.1 - 3.5e-77 259.3 0.0 3.9e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08981.1 - 7.1e-41 140.2 0.0 8.4e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08981.1 - 2.8e-13 49.9 0.0 1.8e-12 47.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KEG08981.1 - 0.00013 22.0 0.2 0.23 11.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KEG08981.1 - 0.00077 19.1 0.2 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KEG08981.1 - 0.00082 18.8 1.0 0.0015 17.9 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEG08981.1 - 0.005 15.8 0.3 0.0072 15.3 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KEG08981.1 - 0.0053 15.8 0.1 0.0096 15.0 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase PF00069.25 KEG08982.1 - 7.2e-76 255.0 0.0 8.1e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG08982.1 - 4.7e-41 140.8 0.0 5.6e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG08982.1 - 1.7e-09 37.4 0.0 3.7e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KEG08982.1 - 0.00035 19.6 0.0 0.00072 18.6 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KEG08982.1 - 0.0021 18.0 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEG08982.1 - 0.0055 16.1 0.2 0.01 15.2 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phosducin PF02114.16 KEG08982.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin Ribosomal_L1 PF00687.21 KEG08984.1 - 4.4e-40 137.6 3.0 5.4e-40 137.3 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_S27e PF01667.17 KEG08985.1 - 5.4e-24 83.7 4.6 6.6e-24 83.4 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 KEG08985.1 - 0.0055 16.9 1.0 0.0073 16.5 1.0 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 KEG08985.1 - 0.032 13.7 1.5 0.051 13.1 1.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 KEG08985.1 - 0.05 13.5 2.5 1.3 9.0 2.5 2.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 KEG08985.1 - 0.62 10.2 0.2 0.62 10.2 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TFIIS_C PF01096.18 KEG08986.1 - 3.1e-12 46.1 8.0 3.1e-12 46.1 8.0 3.5 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) aGPT-Pplase3 PF18746.1 KEG08986.1 - 0.24 10.7 2.1 8.7 5.6 1.7 2.1 1 1 1 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 IQ PF00612.27 KEG08987.1 - 0.11 12.4 2.1 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif CDC45 PF02724.14 KEG08988.1 - 0.019 13.3 2.6 0.021 13.1 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KEG08988.1 - 0.034 12.4 5.1 0.042 12.1 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L26 PF16906.5 KEG08988.1 - 0.078 13.5 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Sigma70_ner PF04546.13 KEG08988.1 - 0.18 11.6 4.8 0.26 11.2 4.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region eIF-3c_N PF05470.12 KEG08988.1 - 0.29 9.4 2.1 0.38 9.0 2.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Rhabdo_ncap PF00945.18 KEG08988.1 - 0.67 8.8 1.5 0.84 8.5 1.5 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4611 PF15387.6 KEG08988.1 - 1.2 9.4 12.9 0.6 10.4 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KEG08988.1 - 1.5 8.0 8.7 2.4 7.4 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KEG08988.1 - 1.9 8.5 4.9 3.1 7.8 4.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KEG08988.1 - 2.5 6.1 12.5 3.1 5.8 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tub_N PF16322.5 KEG08988.1 - 4.8 7.5 14.5 8.7 6.7 14.5 1.4 1 1 0 1 1 1 0 Tubby N-terminal RRN3 PF05327.11 KEG08988.1 - 5.8 5.3 5.9 7.5 5.0 5.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glycos_transf_4 PF00953.21 KEG08989.1 - 1.4e-41 142.2 5.9 1.4e-41 142.2 5.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 Sld5 PF05916.11 KEG08990.1 - 3.2e-13 50.1 0.0 4.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Med3 PF11593.8 KEG08990.1 - 0.075 12.2 5.3 0.091 11.9 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arrestin_N PF00339.29 KEG08991.1 - 1.5e-07 31.6 3.5 6.4e-07 29.5 0.1 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF2098 PF09871.9 KEG08991.1 - 0.017 15.5 3.2 0.041 14.2 3.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) LDB19 PF13002.7 KEG08991.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Paf1 PF03985.13 KEG08991.1 - 0.45 9.5 11.9 0.59 9.1 11.9 1.2 1 0 0 1 1 1 0 Paf1 Cas_Csy4 PF09618.10 KEG08991.1 - 0.7 10.0 4.1 1.1 9.3 4.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Rgp1 PF08737.10 KEG08991.1 - 1.2 8.3 6.7 0.21 10.7 0.3 2.1 2 0 0 2 2 2 0 Rgp1 CDC45 PF02724.14 KEG08991.1 - 2.1 6.5 6.7 3 6.0 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KEG08991.1 - 4.4 6.0 4.1 6.2 5.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KEG08991.1 - 7.1 6.4 11.3 12 5.6 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spo0M PF07070.11 KEG08992.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 SpoOM protein Skp1_POZ PF03931.15 KEG08993.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain NGP1NT PF08153.12 KEG08994.1 - 8.7e-44 148.8 0.7 8.7e-44 148.8 0.7 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KEG08994.1 - 2.6e-18 66.2 0.1 9.2e-15 54.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG08994.1 - 3.4e-05 23.4 0.1 8e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEG08994.1 - 0.00069 19.7 7.1 0.53 10.3 0.0 4.0 3 2 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 KEG08994.1 - 0.0033 17.0 0.2 2.1 7.8 0.0 3.7 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEG08994.1 - 0.0066 16.4 0.0 0.049 13.5 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KEG08994.1 - 0.022 15.2 0.0 0.17 12.2 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain Hc1 PF07432.13 KEG08994.1 - 3.7 7.9 10.8 1.9 8.8 1.3 2.7 2 0 0 2 2 2 0 Histone H1-like protein Hc1 MFS_1 PF07690.16 KEG08995.1 - 1.3e-30 106.5 48.8 4e-24 85.2 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_ab PF00006.25 KEG08997.1 - 7.4e-67 225.1 0.1 1.2e-66 224.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KEG08997.1 - 6.5e-09 36.2 0.6 3e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain YqfQ PF14181.6 KEG08997.1 - 4.8 7.3 9.3 15 5.7 9.3 1.9 1 0 0 1 1 1 0 YqfQ-like protein ADH_N PF08240.12 KEG08998.1 - 0.00019 21.3 0.7 0.001 18.9 0.1 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 KEG08998.1 - 0.021 15.1 0.3 0.042 14.1 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Phage_holin_3_5 PF16085.5 KEG08998.1 - 0.14 12.3 0.6 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III ADH_zinc_N PF00107.26 KEG08999.1 - 2.3e-06 27.6 0.2 2.8e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RRM_1 PF00076.22 KEG09001.1 - 4.1e-14 52.2 0.0 5.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3464 PF11947.8 KEG09001.1 - 0.007 16.1 0.4 0.01 15.6 0.4 1.1 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Androgen_recep PF02166.16 KEG09001.1 - 0.06 12.2 3.8 0.063 12.1 3.8 1.1 1 0 0 1 1 1 0 Androgen receptor MctB PF11382.8 KEG09001.1 - 0.13 11.9 0.5 0.16 11.7 0.5 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF2722 PF10846.8 KEG09001.1 - 1.1 8.2 10.7 1.1 8.1 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 KEG09001.1 - 2.1 7.3 6.3 2.6 7.0 6.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RIH_assoc PF08454.11 KEG09002.1 - 1e-27 95.9 1.4 5.4e-27 93.6 1.4 2.3 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 KEG09002.1 - 7.4e-13 48.3 13.1 7.4e-13 48.3 13.1 2.5 3 1 0 3 3 3 1 Ion transport protein Fer2_4 PF13510.6 KEG09002.1 - 0.9 9.6 3.7 12 6.0 0.0 3.1 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Ins145_P3_rec PF08709.11 KEG09003.1 - 1.9e-43 148.1 0.0 3.7e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 KEG09003.1 - 5e-11 42.4 0.0 5.8e-10 38.9 0.0 2.5 2 0 0 2 2 2 1 RIH domain APG6_N PF17675.1 KEG09004.1 - 0.0025 18.4 24.3 0.074 13.6 11.3 2.9 2 0 0 2 2 2 2 Apg6 coiled-coil region ATG16 PF08614.11 KEG09004.1 - 0.0062 16.8 17.8 0.0062 16.8 17.8 2.9 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KEG09004.1 - 0.17 12.0 2.5 0.24 11.4 1.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) PROL5-SMR PF15621.6 KEG09004.1 - 0.2 12.2 11.5 0.65 10.5 11.5 1.9 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF4407 PF14362.6 KEG09004.1 - 0.24 10.7 15.9 0.053 12.9 8.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KxDL PF10241.9 KEG09004.1 - 0.3 11.4 8.5 0.52 10.6 6.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Hemagglutinin PF00509.18 KEG09004.1 - 0.32 9.4 0.7 0.51 8.7 0.7 1.2 1 0 0 1 1 1 0 Haemagglutinin RmuC PF02646.16 KEG09004.1 - 0.32 10.1 6.1 0.67 9.0 6.1 1.5 1 0 0 1 1 1 0 RmuC family Exonuc_VII_L PF02601.15 KEG09004.1 - 0.33 10.5 11.6 0.3 10.6 3.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 KEG09004.1 - 0.4 11.1 3.7 2.1 8.8 0.8 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bap31_Bap29_C PF18035.1 KEG09004.1 - 0.58 10.2 16.5 0.41 10.7 2.8 2.6 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FemAB PF02388.16 KEG09004.1 - 0.71 8.7 4.4 1.3 7.8 4.4 1.3 1 0 0 1 1 1 0 FemAB family PI3K_P85_iSH2 PF16454.5 KEG09004.1 - 0.94 9.1 19.9 0.017 14.7 9.4 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 KEG09004.1 - 2 7.2 19.8 0.3 9.9 7.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein RasGAP_C PF03836.15 KEG09004.1 - 2.5 8.3 8.1 0.99 9.5 4.2 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Lebercilin PF15619.6 KEG09004.1 - 4 7.1 32.2 2 8.0 14.9 3.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 KEG09004.1 - 4.6 5.1 6.5 0.39 8.6 1.9 1.5 2 0 0 2 2 2 0 Prominin PilJ PF13675.6 KEG09004.1 - 7.5 6.6 10.3 7.6 6.6 4.5 2.8 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CdvA PF18822.1 KEG09004.1 - 9.4 6.1 15.9 1.7 8.5 5.5 3.5 3 1 0 3 3 3 0 CdvA-like coiled-coil domain FapA PF03961.13 KEG09004.1 - 9.4 4.7 14.5 2.6 6.6 6.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Ras PF00071.22 KEG09005.1 - 1.5e-58 197.0 0.0 1.7e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG09005.1 - 5.7e-32 110.5 0.0 8.2e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG09005.1 - 2.4e-14 53.2 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEG09005.1 - 3.8e-06 26.6 0.0 0.00044 19.9 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG09005.1 - 5.5e-05 23.2 0.0 7.8e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DNA_pol3_delta PF06144.13 KEG09005.1 - 0.022 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Gtr1_RagA PF04670.12 KEG09005.1 - 0.035 13.5 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KEG09005.1 - 0.043 13.7 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KEG09005.1 - 0.05 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.25 KEG09006.1 - 1.5e-43 149.1 0.0 5.1e-38 131.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09006.1 - 5.6e-24 84.8 0.0 2.9e-23 82.5 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG09006.1 - 0.016 14.0 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KEG09006.1 - 0.14 11.4 0.0 0.76 9.0 0.0 2.1 2 1 0 2 2 2 0 Kinase-like CH PF00307.31 KEG09007.1 - 0.00063 19.9 0.0 0.00097 19.3 0.0 1.3 1 1 0 1 1 1 1 Calponin homology (CH) domain zf-C2H2_4 PF13894.6 KEG09008.1 - 4.3e-06 27.1 30.5 0.19 12.7 1.1 5.9 5 1 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEG09008.1 - 4.4e-06 26.9 1.9 4.4e-06 26.9 1.9 6.8 7 1 0 7 7 7 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KEG09008.1 - 0.00025 21.7 0.3 0.01 16.5 0.1 2.7 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KEG09008.1 - 0.0005 20.0 10.8 0.084 12.9 0.0 4.9 4 1 1 5 5 5 1 BED zinc finger Fer2_2 PF01799.20 KEG09008.1 - 0.012 15.6 0.2 2.8 8.0 0.0 3.2 3 0 0 3 3 3 0 [2Fe-2S] binding domain Sgf11 PF08209.11 KEG09008.1 - 0.056 13.0 5.7 0.068 12.7 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF629 PF04780.12 KEG09008.1 - 0.12 10.9 0.9 8.3 4.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-HYPF PF07503.12 KEG09008.1 - 0.25 11.1 6.6 0.75 9.6 0.1 3.2 3 0 0 3 3 3 0 HypF finger zf-MYST PF17772.1 KEG09008.1 - 0.25 11.0 6.8 2.7 7.7 0.2 3.1 3 0 0 3 3 3 0 MYST family zinc finger domain RNHCP PF12647.7 KEG09008.1 - 0.29 11.1 6.7 13 5.8 0.1 3.3 3 0 0 3 3 3 0 RNHCP domain zf-C2H2 PF00096.26 KEG09008.1 - 0.56 10.8 0.1 0.081 13.4 1.8 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type DNA_binding_1 PF01035.20 KEG09009.1 - 3.1e-27 94.5 0.3 4.6e-27 94.0 0.3 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Cnd1 PF12717.7 KEG09010.1 - 0.0027 17.8 0.4 0.065 13.3 0.1 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Chromadorea_ALT PF05535.12 KEG09010.1 - 0.21 11.8 0.4 0.5 10.6 0.4 1.5 1 0 0 1 1 1 0 Chromadorea ALT protein HEAT PF02985.22 KEG09010.1 - 0.3 11.4 11.9 13 6.3 0.1 6.1 5 0 0 5 5 5 0 HEAT repeat FdhE PF04216.12 KEG09011.1 - 0.09 12.6 3.7 0.098 12.5 3.7 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Kinesin PF00225.23 KEG09012.1 - 3.1e-06 26.4 0.0 2.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG09012.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding CAP_N PF01213.19 KEG09012.1 - 3.2 7.1 13.2 0.11 12.0 1.3 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal COX17 PF05051.13 KEG09013.1 - 3.6e-06 27.2 0.4 5.5e-06 26.6 0.4 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Thiolase_N PF00108.23 KEG09014.1 - 5e-14 52.3 0.7 1.4e-10 41.0 0.1 2.6 3 0 0 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEG09014.1 - 1.5e-13 50.5 0.2 3e-12 46.2 0.1 2.6 1 1 1 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEG09014.1 - 1.9e-08 34.2 2.7 7e-08 32.4 0.7 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEG09014.1 - 0.025 14.6 0.9 0.48 10.4 0.7 2.9 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain PriCT_2 PF08707.11 KEG09015.1 - 6.2e-08 32.9 4.4 1.4e-07 31.8 1.1 2.4 1 1 1 2 2 2 1 Primase C terminal 2 (PriCT-2) PPL5 PF18168.1 KEG09015.1 - 1.3e-07 31.3 4.0 8.9e-06 25.2 0.0 2.9 2 1 1 3 3 3 2 Prim-pol family 5 GFO_IDH_MocA PF01408.22 KEG09016.1 - 0.00081 20.2 0.0 0.0015 19.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.22 KEG09017.1 - 1.2e-08 35.8 0.0 2.4e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DIM1 PF02966.16 KEG09018.1 - 5.3e-34 116.8 0.0 3e-27 95.0 0.0 2.1 2 0 0 2 2 2 2 Mitosis protein DIM1 Tim17 PF02466.19 KEG09020.1 - 2.3e-17 63.4 10.5 3.6e-17 62.7 10.5 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family G0-G1_switch_2 PF15103.6 KEG09020.1 - 0.67 10.4 2.2 3.1 8.3 0.2 2.1 1 1 1 2 2 2 0 G0/G1 switch protein 2 MRP PF09387.10 KEG09021.1 - 9.7e-61 205.2 0.3 1.2e-60 204.9 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Zip PF02535.22 KEG09022.1 - 1.6 7.9 8.5 2.2 7.4 8.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4200 PF13863.6 KEG09023.1 - 0.00023 21.5 4.0 0.00023 21.5 4.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) AIP3 PF03915.13 KEG09023.1 - 0.00093 18.4 5.1 0.0014 17.8 5.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 HMMR_N PF15905.5 KEG09023.1 - 0.0073 15.8 4.9 0.0073 15.8 4.9 2.1 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 KEG09023.1 - 0.0083 15.5 8.4 0.08 12.3 8.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) EzrA PF06160.12 KEG09023.1 - 0.0085 14.3 3.8 0.014 13.6 3.6 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA DUF641 PF04859.12 KEG09023.1 - 0.0088 16.4 9.6 0.038 14.3 0.4 2.8 1 1 2 3 3 3 1 Plant protein of unknown function (DUF641) DUF4795 PF16043.5 KEG09023.1 - 0.01 15.5 6.0 0.016 14.8 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) HIP1_clath_bdg PF16515.5 KEG09023.1 - 0.024 15.2 13.4 0.18 12.5 0.4 3.4 3 1 1 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin PF00261.20 KEG09023.1 - 0.032 13.6 12.2 0.55 9.6 0.5 2.4 1 1 1 2 2 2 0 Tropomyosin AAA_13 PF13166.6 KEG09023.1 - 0.034 12.8 2.4 0.044 12.4 2.4 1.2 1 0 0 1 1 1 0 AAA domain MAD PF05557.13 KEG09023.1 - 0.036 12.4 11.3 10 4.3 3.1 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein TPD52 PF04201.15 KEG09023.1 - 0.042 13.5 2.5 0.044 13.4 0.1 2.2 2 1 1 3 3 3 0 Tumour protein D52 family Spc7 PF08317.11 KEG09023.1 - 0.043 12.7 10.1 0.69 8.7 0.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KEG09023.1 - 0.049 13.6 6.3 4.3 7.3 0.0 3.4 3 1 0 3 3 3 0 Prefoldin subunit OmpH PF03938.14 KEG09023.1 - 0.05 13.9 8.0 16 5.9 8.5 3.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) LPP PF04728.13 KEG09023.1 - 0.094 13.1 2.9 22 5.6 0.1 3.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Leu_zip PF15294.6 KEG09023.1 - 0.1 12.1 7.8 1.7 8.1 2.5 2.2 1 1 1 2 2 2 0 Leucine zipper Filament PF00038.21 KEG09023.1 - 0.1 12.2 12.2 0.035 13.7 7.2 2.0 1 1 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 KEG09023.1 - 0.12 12.4 5.8 7.7 6.6 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 KEG09023.1 - 0.14 12.1 10.8 6.9 6.7 1.4 3.5 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 KEG09023.1 - 0.18 12.0 13.0 1.2 9.3 10.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) End3 PF12761.7 KEG09023.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.5 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF1640 PF07798.11 KEG09023.1 - 0.21 11.6 8.6 1.3 9.0 6.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) GAS PF13851.6 KEG09023.1 - 0.22 10.9 10.3 0.25 10.7 7.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KEG09023.1 - 0.23 12.0 6.1 0.21 12.2 1.0 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fez1 PF06818.15 KEG09023.1 - 0.25 11.8 10.4 0.63 10.5 10.6 1.6 1 1 0 1 1 1 0 Fez1 Baculo_PEP_C PF04513.12 KEG09023.1 - 0.33 11.0 3.6 1.6 8.7 1.9 2.5 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31_Bap29_C PF18035.1 KEG09023.1 - 0.38 10.8 9.1 1.2 9.2 0.4 3.5 4 0 0 4 4 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain WXG100 PF06013.12 KEG09023.1 - 0.56 10.5 4.5 0.59 10.4 0.2 3.1 3 1 0 3 3 2 0 Proteins of 100 residues with WXG ADIP PF11559.8 KEG09023.1 - 0.56 10.3 13.2 0.04 14.0 2.0 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Plasmid_RAQPRD PF09686.10 KEG09023.1 - 0.91 9.8 9.3 5.8 7.2 0.9 3.3 4 1 1 5 5 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) YabA PF06156.13 KEG09023.1 - 1.1 10.0 8.0 25 5.6 0.2 3.1 1 1 1 2 2 2 0 Initiation control protein YabA COG2 PF06148.11 KEG09023.1 - 1.3 9.1 6.8 3.7 7.6 0.1 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SOGA PF11365.8 KEG09023.1 - 1.3 10.2 7.3 6.7 7.9 0.4 2.6 1 1 1 2 2 2 0 Protein SOGA DUF2203 PF09969.9 KEG09023.1 - 1.4 9.7 8.4 3.5 8.4 0.5 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.8 KEG09023.1 - 1.8 8.8 12.1 0.61 10.3 3.7 3.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Rootletin PF15035.6 KEG09023.1 - 2.2 8.2 11.8 5 7.1 0.6 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TMCO5 PF14992.6 KEG09023.1 - 2.3 7.7 8.4 2.6 7.6 6.3 1.7 1 1 0 1 1 1 0 TMCO5 family Atg14 PF10186.9 KEG09023.1 - 2.6 7.1 7.7 22 4.0 7.7 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 KEG09023.1 - 2.8 7.7 13.4 4 7.2 11.8 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family APG6_N PF17675.1 KEG09023.1 - 3.5 8.2 15.4 1.4 9.4 3.3 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region THOC7 PF05615.13 KEG09023.1 - 3.6 7.9 11.9 2.2 8.5 6.3 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 SlyX PF04102.12 KEG09023.1 - 4.5 8.0 11.1 15 6.3 0.3 4.0 2 1 2 4 4 4 0 SlyX CENP-F_leu_zip PF10473.9 KEG09023.1 - 5.3 7.1 11.9 1.9 8.5 3.9 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KEG09023.1 - 5.3 6.3 13.1 0.28 10.5 0.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TSNAXIP1_N PF15739.5 KEG09023.1 - 5.7 7.4 11.4 0.49 10.8 1.9 2.8 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Mod_r PF07200.13 KEG09023.1 - 6 7.0 10.3 2.2 8.4 0.7 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fungal_TACC PF12709.7 KEG09023.1 - 6.8 7.2 10.0 9.7 6.7 0.6 3.5 3 2 2 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins GTP_EFTU PF00009.27 KEG09024.1 - 3.4e-22 79.0 0.0 1.4e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 KEG09024.1 - 7.6e-15 54.9 0.0 2e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 KEG09024.1 - 0.0011 19.3 0.3 0.61 10.5 0.7 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEG09024.1 - 0.0022 18.1 0.0 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG09024.1 - 0.0037 17.2 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Zn-ribbon_8 PF09723.10 KEG09024.1 - 0.0068 16.5 1.2 0.019 15.1 1.2 1.8 1 0 0 1 1 1 1 Zinc ribbon domain MMR_HSR1_Xtn PF16897.5 KEG09024.1 - 0.09 12.8 0.1 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 KEG09026.1 - 2e-35 122.1 0.0 2e-35 122.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KEG09026.1 - 9.2e-16 57.9 0.1 2.9e-15 56.3 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KEG09026.1 - 6.3e-12 45.7 0.0 1e-06 29.0 0.0 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KEG09026.1 - 8e-10 38.5 0.2 2.7e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KEG09026.1 - 6.4e-08 32.7 0.1 5.1e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KEG09026.1 - 0.00027 21.1 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KEG09026.1 - 0.0013 18.6 0.0 0.0046 16.8 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KEG09026.1 - 0.026 14.1 0.0 0.19 11.4 0.0 2.6 2 1 0 2 2 2 0 Ras family ALP_N PF17989.1 KEG09028.1 - 0.014 15.6 0.1 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Actin like proteins N terminal domain DUF4520 PF15016.6 KEG09029.1 - 8.9e-20 70.6 0.1 7.7e-19 67.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) DUF4524 PF15025.6 KEG09029.1 - 0.03 14.1 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) COG5 PF10392.9 KEG09030.1 - 0.062 13.5 2.2 0.11 12.7 2.2 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KEG09030.1 - 0.086 12.7 0.9 3.6 7.5 1.3 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Peptidase_M8 PF01457.16 KEG09031.1 - 9.1e-153 509.7 0.6 1.1e-152 509.5 0.6 1.0 1 0 0 1 1 1 1 Leishmanolysin Astacin PF01400.24 KEG09031.1 - 0.07 12.7 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M8 PF01457.16 KEG09032.1 - 1.5e-155 518.9 0.2 2.2e-155 518.4 0.2 1.2 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.6 KEG09032.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 MFS_1 PF07690.16 KEG09040.1 - 1.3e-10 40.7 14.7 1.3e-10 40.7 14.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG09040.1 - 0.0041 16.6 10.1 0.0041 16.6 10.1 2.6 2 1 0 2 2 2 1 Nodulin-like DUF3290 PF11694.8 KEG09040.1 - 5 7.1 5.9 0.46 10.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Spem1 PF15670.5 KEG09041.1 - 5.1 6.6 11.9 1 8.9 6.4 2.4 3 0 0 3 3 3 0 Spermatid maturation protein 1 LysM PF01476.20 KEG09043.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain YL1 PF05764.13 KEG09043.1 - 3.3 7.8 6.4 0.5 10.4 2.1 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Clat_adaptor_s PF01217.20 KEG09044.1 - 2.7e-50 170.0 1.8 3.1e-50 169.8 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Clathrin PF00637.20 KEG09046.1 - 5.3e-06 26.4 0.0 1.9e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.6 KEG09046.1 - 0.0075 16.6 1.2 0.03 14.6 1.2 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEG09046.1 - 0.02 14.6 0.2 0.068 12.9 0.2 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEG09046.1 - 0.2 11.5 2.1 0.62 9.9 2.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG09046.1 - 0.76 9.8 6.4 0.27 11.2 2.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain RNase_PH PF01138.21 KEG09047.1 - 3.5e-16 59.9 1.7 7.6e-16 58.8 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Amastin PF07344.11 KEG09048.1 - 3.1e-16 59.6 9.9 4.2e-16 59.2 9.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 KEG09048.1 - 0.45 10.1 13.8 1.4 8.5 10.1 2.1 2 0 0 2 2 2 0 SUR7/PalI family TssN PF17555.2 KEG09048.1 - 5.5 6.3 10.5 1.1 8.6 6.2 2.0 2 1 0 2 2 2 0 Type VI secretion system, TssN LRR_4 PF12799.7 KEG09049.1 - 6.3e-12 45.5 9.9 9.3e-05 22.7 2.0 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG09049.1 - 5.6e-10 39.0 0.3 1.4e-05 24.7 0.0 2.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KEG09049.1 - 1.9e-08 33.9 10.0 0.0012 18.6 2.6 4.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KEG09049.1 - 0.027 14.5 1.1 22 5.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KEG09049.1 - 0.52 11.1 9.2 64 4.7 0.7 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat ARGLU PF15346.6 KEG09050.1 - 0.0026 17.6 11.0 0.003 17.5 11.0 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Nucleo_P87 PF07267.11 KEG09050.1 - 0.011 14.7 0.1 0.011 14.6 0.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Atg14 PF10186.9 KEG09050.1 - 0.024 13.8 3.8 0.028 13.5 3.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEG09050.1 - 0.029 13.3 6.0 0.033 13.1 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KEG09050.1 - 0.034 13.5 5.3 0.037 13.4 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KEG09050.1 - 0.085 13.4 11.6 1.2 9.6 9.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0449 PF15136.6 KEG09050.1 - 0.15 12.5 5.0 0.17 12.4 0.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF3584 PF12128.8 KEG09050.1 - 0.29 8.6 8.9 0.31 8.5 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sipho_Gp157 PF05565.11 KEG09050.1 - 1.3 9.0 6.9 6 6.8 6.8 1.8 1 1 1 2 2 2 0 Siphovirus Gp157 MerR-DNA-bind PF09278.11 KEG09050.1 - 2.4 8.7 9.3 5.7 7.5 0.3 2.6 2 1 0 2 2 2 0 MerR, DNA binding FUSC PF04632.12 KEG09050.1 - 6.3 5.2 7.4 7.6 4.9 7.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family vATP-synt_E PF01991.18 KEG09052.1 - 6.9e-41 139.9 8.9 7.8e-41 139.7 8.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DZR PF12773.7 KEG09053.1 - 0.0011 18.9 0.3 0.0017 18.4 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KEG09053.1 - 0.026 13.9 1.3 0.049 13.1 1.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Sox17_18_mid PF12067.8 KEG09053.1 - 0.063 13.3 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Sox 17/18 central domain zinc_ribbon_2 PF13240.6 KEG09053.1 - 0.09 12.5 2.8 0.22 11.3 2.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain BPL_LplA_LipB PF03099.19 KEG09055.1 - 0.00015 21.6 0.0 0.00051 20.0 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RNase_H PF00075.24 KEG09057.1 - 9.7e-08 32.3 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KEG09058.1 - 5.6e-35 120.9 0.2 1.1e-18 67.6 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KEG09059.1 - 0.082 12.4 0.0 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase_6 PF13344.6 KEG09062.1 - 2.7e-18 65.9 0.0 5.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEG09062.1 - 4.2e-16 58.8 0.1 1.2e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KEG09062.1 - 1.9e-06 28.3 0.1 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KEG09062.1 - 6.5e-05 22.6 0.0 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase HAD_2 PF13419.6 KEG09062.1 - 0.00068 19.8 0.0 0.0028 17.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PEMT PF04191.13 KEG09063.1 - 1.1e-26 93.2 5.0 2.2e-26 92.3 4.3 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Peptidase_M1 PF01433.20 KEG09064.1 - 1.9e-07 30.9 0.0 7.5e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KEG09064.1 - 2.5e-07 31.1 0.0 4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain SPDY PF03771.16 KEG09064.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF317) ECH_1 PF00378.20 KEG09065.1 - 6.8e-52 176.3 0.0 9e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEG09065.1 - 2.7e-14 53.4 0.0 9.1e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KEG09065.1 - 0.018 15.0 0.3 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Peripla_BP_6 PF13458.6 KEG09067.1 - 1e-11 45.1 0.0 9.9e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein CENP-H PF05837.12 KEG09068.1 - 0.017 15.5 2.4 0.017 15.5 2.4 2.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF2521 PF10730.9 KEG09068.1 - 0.044 13.8 1.4 0.097 12.7 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) FAM165 PF14981.6 KEG09068.1 - 0.42 10.5 1.9 0.82 9.5 0.1 2.2 2 0 0 2 2 2 0 FAM165 family HTH_29 PF13551.6 KEG09069.1 - 0.29 11.2 1.8 0.38 10.8 0.3 1.9 3 0 0 3 3 3 0 Winged helix-turn helix WD40 PF00400.32 KEG09070.1 - 1.2e-13 51.2 16.4 0.0081 17.0 0.2 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat NLE PF08154.12 KEG09070.1 - 5e-13 49.4 0.2 7.9e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KEG09070.1 - 0.0074 16.6 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Guanylate_cyc PF00211.20 KEG09072.1 - 3e-11 43.3 0.0 5.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_1 PF00515.28 KEG09075.1 - 5.2e-23 79.8 10.4 0.0008 19.1 0.2 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEG09075.1 - 4.8e-22 76.2 16.4 0.00025 20.9 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09075.1 - 1.2e-14 53.7 6.7 6.7e-09 35.3 0.2 5.1 5 0 0 5 5 5 3 TPR repeat DnaJ PF00226.31 KEG09075.1 - 1.9e-10 40.7 0.0 6.2e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.6 KEG09075.1 - 1.8e-08 33.9 5.0 0.11 12.7 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09075.1 - 7.6e-07 29.6 13.4 0.017 15.6 0.7 5.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEG09075.1 - 8.5e-07 28.9 9.7 0.002 18.3 0.3 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG09075.1 - 0.00012 22.6 23.3 0.047 14.5 0.2 6.8 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG09075.1 - 0.00048 20.7 26.2 0.00064 20.3 0.2 6.8 5 2 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09075.1 - 0.0016 18.7 19.4 0.024 14.9 0.2 5.6 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG09075.1 - 0.024 14.7 3.8 42 4.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG09075.1 - 0.055 13.6 21.1 1.1 9.5 0.7 5.9 5 2 1 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG09075.1 - 0.088 13.5 8.7 4.2 8.2 0.1 5.4 6 0 0 6 6 3 0 Tetratricopeptide repeat BTAD PF03704.17 KEG09075.1 - 2.8 8.4 26.8 1.3 9.4 0.9 5.5 3 2 2 5 5 5 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 KEG09076.1 - 7.2e-08 32.1 0.0 3.5e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 XPC-binding domain E1_dh PF00676.20 KEG09078.1 - 7.5e-100 333.7 0.0 8.8e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEG09078.1 - 0.023 13.9 0.1 0.046 12.9 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase HSP70 PF00012.20 KEG09079.1 - 3.3e-114 382.3 1.3 3.4e-114 382.2 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KEG09079.1 - 0.008 15.0 0.0 0.041 12.7 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein Peptidase_S39 PF02122.15 KEG09079.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase S39 SBDS_C PF09377.10 KEG09079.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 SBDS protein C-terminal domain FGGY_C PF02782.16 KEG09079.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain CCDC53 PF10152.9 KEG09079.1 - 6.4 7.2 13.3 1.9 8.9 6.1 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EzrA PF06160.12 KEG09080.1 - 0.0005 18.4 2.8 0.0005 18.4 2.8 4.7 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA ATG16 PF08614.11 KEG09080.1 - 0.001 19.3 4.3 0.001 19.3 4.3 7.7 2 1 4 7 7 7 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KEG09080.1 - 0.0012 17.8 113.4 0.12 11.3 21.9 5.8 2 1 4 6 6 6 4 Spc7 kinetochore protein Leu_zip PF15294.6 KEG09080.1 - 0.0066 16.0 21.0 0.0066 16.0 21.0 5.1 1 1 3 5 5 5 1 Leucine zipper DUF3783 PF12646.7 KEG09080.1 - 0.13 12.2 0.9 0.88 9.6 0.9 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) DUF19 PF01579.18 KEG09080.1 - 0.81 9.5 4.9 0.55 10.0 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF19) Laminin_II PF06009.12 KEG09080.1 - 0.97 9.5 67.4 0.26 11.3 1.9 8.1 3 1 4 8 8 8 0 Laminin Domain II DUF1664 PF07889.12 KEG09080.1 - 3.4 7.7 65.4 0.037 14.1 2.8 8.5 3 3 6 9 9 9 0 Protein of unknown function (DUF1664) PI_PP_I PF18363.1 KEG09080.1 - 4.8 7.4 8.9 8.4 6.7 0.3 4.5 2 2 3 5 5 5 0 Phosphoinositide phosphatase insertion domain CorA PF01544.18 KEG09082.1 - 1.4e-27 96.8 2.7 1.5e-23 83.5 1.3 2.5 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein RBP_receptor PF14752.6 KEG09082.1 - 0.026 13.1 0.5 0.041 12.4 0.5 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor PX PF00787.24 KEG09084.1 - 7.1e-20 71.1 0.1 5.4e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 PX domain AAA_16 PF13191.6 KEG09085.1 - 4.7e-05 23.8 0.2 0.00015 22.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEG09085.1 - 0.0031 17.2 0.1 0.0097 15.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain G-alpha PF00503.20 KEG09085.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MCM PF00493.23 KEG09085.1 - 0.034 13.3 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 KEG09085.1 - 0.035 13.5 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KEG09085.1 - 0.082 13.2 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 KEG09086.1 - 3.7e-32 111.4 12.8 5.5e-32 110.9 12.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KEG09086.1 - 5.3e-25 88.5 0.1 7.8e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG09086.1 - 2.8e-07 30.6 0.5 0.015 15.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEG09086.1 - 0.00054 20.4 0.1 0.0024 18.3 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEG09086.1 - 0.00076 19.8 0.2 0.0056 17.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KEG09086.1 - 0.00085 18.8 0.2 0.41 10.0 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG09086.1 - 0.0012 18.5 0.1 0.0026 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEG09086.1 - 0.0023 17.9 0.1 0.0052 16.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 KEG09086.1 - 0.047 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KEG09086.1 - 0.051 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KEG09086.1 - 0.073 12.8 0.0 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 KEG09086.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KEG09086.1 - 0.097 13.2 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KEG09086.1 - 0.12 12.1 0.1 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 KEG09086.1 - 0.16 12.1 0.1 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 KEG09087.1 - 2.7e-06 27.0 4.7 4.2e-06 26.3 4.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter SoxE PF06525.11 KEG09087.1 - 0.089 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain DUF2677 PF10838.8 KEG09088.1 - 0.15 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) Glyco_hydro_47 PF01532.20 KEG09089.1 - 1.8e-99 333.8 0.0 4.6e-99 332.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4159 PF13709.6 KEG09089.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Glyco_hydro_127 PF07944.12 KEG09089.1 - 0.18 10.3 0.0 4.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Cnd1 PF12717.7 KEG09090.1 - 0.05 13.6 1.9 5.5 7.0 1.9 2.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CSN5_C PF18323.1 KEG09090.1 - 1.1 10.2 4.9 0.85 10.6 0.3 2.7 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF229 PF02995.17 KEG09091.1 - 2.5e-19 69.3 0.0 6.2e-19 68.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) CheR_N PF03705.15 KEG09091.1 - 0.088 12.5 3.9 0.079 12.7 2.1 1.9 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain CH PF00307.31 KEG09092.1 - 0.0011 19.1 0.0 0.0037 17.4 0.0 2.0 1 1 0 1 1 1 1 Calponin homology (CH) domain ATE_N PF04376.13 KEG09092.1 - 0.094 13.1 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Ammonium_transp PF00909.21 KEG09094.1 - 2.6e-12 46.2 2.5 2.8e-12 46.1 2.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF5325 PF17259.2 KEG09094.1 - 0.0029 17.4 1.2 0.0046 16.8 1.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5325) TCTP PF00838.17 KEG09095.1 - 4.4e-37 128.0 0.5 4.8e-37 127.9 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UPF0262 PF06793.12 KEG09095.1 - 0.0044 17.1 0.2 0.0057 16.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) DUF273 PF03314.14 KEG09095.1 - 0.04 13.5 0.5 1.7 8.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF273 RICH PF05062.12 KEG09095.1 - 0.069 13.5 0.4 0.12 12.8 0.4 1.3 1 0 0 1 1 1 0 RICH domain Ribosomal_S20p PF01649.18 KEG09095.1 - 0.071 13.7 0.7 0.099 13.3 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 ERCC4 PF02732.15 KEG09096.1 - 5.8e-18 65.6 0.0 2.4e-17 63.5 0.0 2.1 3 0 0 3 3 3 1 ERCC4 domain SAP PF02037.27 KEG09096.1 - 1.1e-07 31.4 3.4 9.9e-07 28.4 0.2 2.5 2 0 0 2 2 2 1 SAP domain DUF2076 PF09849.9 KEG09096.1 - 9.1 6.2 14.4 15 5.5 14.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Prominin PF05478.11 KEG09097.1 - 0.0063 14.5 0.7 0.0063 14.5 0.7 2.3 1 1 1 2 2 2 1 Prominin Corona_S2 PF01601.16 KEG09097.1 - 0.4 9.1 13.4 0.68 8.4 1.3 2.3 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein RecQ_Zn_bind PF16124.5 KEG09098.1 - 4.8e-15 56.0 1.0 1.2e-14 54.7 1.0 1.8 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 KEG09098.1 - 5e-14 52.5 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG09098.1 - 2.3e-13 50.4 0.0 9.7e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 KEG09098.1 - 2.8e-09 36.8 0.1 6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 HRDC domain Clat_adaptor_s PF01217.20 KEG09099.1 - 1.4e-42 145.0 0.5 1.6e-42 144.8 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KEG09099.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 p450 PF00067.22 KEG09100.1 - 1.2e-65 222.1 0.0 1.5e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHHC PF01529.20 KEG09101.1 - 1.3e-26 93.3 11.3 1.3e-26 93.3 11.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.25 KEG09103.1 - 5.9e-47 160.2 0.0 1e-46 159.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09103.1 - 7.4e-31 107.4 0.0 1.6e-27 96.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG09103.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEG09103.1 - 0.0037 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KEG09103.1 - 0.052 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KEG09103.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAM2 PF07145.15 KEG09104.1 - 0.054 13.2 0.1 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region His_Phos_1 PF00300.22 KEG09105.1 - 2.2e-16 60.1 0.0 5.5e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SecE PF00584.20 KEG09105.1 - 7.7 6.5 8.8 4.1 7.4 0.0 2.8 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 KEG09106.1 - 3.4e-06 26.8 0.1 3.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.15 KEG09106.1 - 0.0025 17.4 2.3 0.034 13.8 0.0 2.6 1 1 1 2 2 2 1 Ataxin-2 C-terminal region PQQ_2 PF13360.6 KEG09107.1 - 5.3e-22 78.6 21.9 2.5e-06 27.2 2.2 8.8 9 1 1 10 10 10 6 PQQ-like domain PQQ PF01011.21 KEG09107.1 - 8.4e-07 28.6 5.9 0.22 11.5 0.0 6.0 6 0 0 6 6 6 3 PQQ enzyme repeat GHMP_kinases_C PF08544.13 KEG09108.1 - 2e-17 63.3 0.1 4.1e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KEG09108.1 - 6.4e-12 45.5 1.1 1.3e-11 44.6 1.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKKbetaNEMObind PF12179.8 KEG09108.1 - 0.12 12.5 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain PDEase_I PF00233.19 KEG09109.1 - 2e-19 70.3 0.0 3.6e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Taxilin PF09728.9 KEG09109.1 - 0.0021 17.3 17.9 0.0059 15.8 0.5 3.1 3 1 0 3 3 3 2 Myosin-like coiled-coil protein Filament PF00038.21 KEG09109.1 - 0.0051 16.4 4.0 0.0051 16.4 4.0 3.3 3 0 0 3 3 3 1 Intermediate filament protein FlxA PF14282.6 KEG09109.1 - 0.011 15.8 3.1 0.011 15.8 3.1 3.5 3 0 0 3 3 3 0 FlxA-like protein Antibiotic_NAT PF02522.14 KEG09109.1 - 0.032 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase ATG16 PF08614.11 KEG09109.1 - 0.2 11.8 34.1 1.2 9.3 7.8 3.7 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 KEG09109.1 - 0.9 9.5 11.9 1.2 9.1 4.5 4.2 5 0 0 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Tho2 PF11262.8 KEG09109.1 - 1.2 8.3 3.3 4.5 6.4 0.1 2.4 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF812 PF05667.11 KEG09109.1 - 1.6 7.5 16.4 0.014 14.3 8.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Leu_zip PF15294.6 KEG09109.1 - 2.3 7.7 19.0 8.3 5.8 0.3 3.5 2 1 0 3 3 3 0 Leucine zipper DUF1664 PF07889.12 KEG09109.1 - 3.5 7.7 5.9 11 6.1 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KEG09109.1 - 3.6 7.7 14.7 0.17 12.0 0.4 3.9 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KEG09109.1 - 5.3 7.4 24.4 25 5.3 17.8 3.2 2 1 0 2 2 2 0 Fez1 ABC_membrane_2 PF06472.15 KEG09110.1 - 4.8e-62 209.8 3.5 6.6e-62 209.4 3.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEG09110.1 - 1e-16 61.7 0.0 2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEG09110.1 - 4.1e-05 23.1 0.2 0.084 12.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEG09110.1 - 0.0057 17.0 0.0 0.017 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KEG09110.1 - 0.0066 17.0 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KEG09110.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_21 PF13304.6 KEG09110.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KEG09110.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG09110.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 KEG09110.1 - 0.031 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain AAA_15 PF13175.6 KEG09110.1 - 0.037 13.7 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEG09110.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KEG09110.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KEG09110.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KEG09110.1 - 0.14 11.9 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEG09110.1 - 0.16 12.4 0.0 0.53 10.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRM13 PF05206.14 KEG09112.1 - 2.6e-39 135.4 0.0 3.3e-29 102.2 0.0 2.8 1 1 1 2 2 2 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 KEG09112.1 - 2.7e-09 36.7 4.5 5.5e-09 35.8 4.5 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 KEG09112.1 - 0.00013 22.0 3.7 0.0013 18.8 3.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 KEG09113.1 - 3.4e-57 193.8 0.0 5.5e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09113.1 - 2.2e-33 115.7 0.0 3.7e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG09113.1 - 2.4e-09 36.9 0.0 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like C1_2 PF03107.16 KEG09113.1 - 0.00028 21.1 4.6 0.00028 21.1 4.6 2.2 2 0 0 2 2 2 1 C1 domain APH PF01636.23 KEG09113.1 - 0.00041 20.4 0.4 0.16 11.9 0.2 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF4423 PF14394.6 KEG09113.1 - 0.035 13.8 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) zf-C2H2_jaz PF12171.8 KEG09113.1 - 0.3 11.4 2.7 0.44 10.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3439 PF11921.8 KEG09113.1 - 0.41 10.6 4.5 1.1 9.2 4.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FYVE_2 PF02318.16 KEG09113.1 - 0.48 10.6 5.4 1.5 9.0 5.4 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 KEG09113.1 - 1.1 9.5 6.1 2.7 8.2 6.1 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger zf-UDP PF14569.6 KEG09113.1 - 2.3 8.4 7.0 7.4 6.8 6.0 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger ZZ PF00569.17 KEG09113.1 - 9.3 6.2 11.5 0.9 9.4 6.4 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type TetR_C_29 PF17938.1 KEG09115.1 - 0.02 14.9 0.1 0.02 14.9 0.1 3.4 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain TssO PF17561.2 KEG09115.1 - 0.21 11.7 3.1 11 6.1 0.3 3.5 2 0 0 2 2 2 0 Type VI secretion system, TssO RCDG1 PF15725.5 KEG09115.1 - 0.76 10.2 9.1 2.1 8.8 5.2 2.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein zf-C2H2_jaz PF12171.8 KEG09121.1 - 0.00082 19.6 0.0 2.7 8.4 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEG09121.1 - 0.0014 18.9 0.1 3.8 8.0 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KEG09121.1 - 0.0014 19.3 11.7 0.045 14.6 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEG09121.1 - 0.0025 18.2 7.8 0.034 14.6 0.2 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KEG09121.1 - 0.0078 16.5 1.0 0.67 10.3 0.0 2.5 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KEG09121.1 - 0.0089 16.3 5.6 0.3 11.4 0.3 3.4 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KEG09121.1 - 0.076 12.9 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KEG09121.1 - 0.5 10.4 0.0 0.5 10.4 0.0 3.4 4 0 0 4 4 4 0 BED zinc finger UPF0547 PF10571.9 KEG09122.1 - 0.0074 16.3 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 UPF0547 PF10571.9 KEG09123.1 - 0.0074 16.3 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Pro_isomerase PF00160.21 KEG09124.1 - 1.5e-46 158.5 0.1 1.8e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WND PF07861.11 KEG09127.1 - 0.069 12.6 0.0 5 6.5 0.0 2.1 2 0 0 2 2 2 0 WisP family N-Terminal Region RVT_1 PF00078.27 KEG09129.1 - 0.00012 21.7 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adipokin_hormo PF06377.11 KEG09132.1 - 0.0097 16.2 0.0 0.045 14.1 0.0 2.1 1 0 0 1 1 1 1 Adipokinetic hormone SUIM_assoc PF16619.5 KEG09132.1 - 0.31 11.1 6.9 0.48 10.5 0.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Herpes_teg_N PF04843.12 KEG09133.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region LRAT PF04970.13 KEG09133.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF4404 PF14357.6 KEG09133.1 - 2 9.1 3.6 1.8 9.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SNF2_N PF00176.23 KEG09134.1 - 8.4e-64 215.5 0.6 1.4e-63 214.7 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG09134.1 - 3.4e-19 69.2 0.0 3.3e-18 66.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG09134.1 - 1.8e-08 34.5 0.0 4.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG09134.1 - 2.5e-06 27.4 0.0 6.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KEG09134.1 - 0.009 14.9 0.0 0.023 13.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Menin PF05053.13 KEG09134.1 - 0.018 13.5 2.1 0.029 12.7 2.1 1.2 1 0 0 1 1 1 0 Menin AChE_tetra PF08674.10 KEG09134.1 - 0.04 13.6 0.3 0.04 13.6 0.3 2.8 4 0 0 4 4 4 0 Acetylcholinesterase tetramerisation domain HDA2-3 PF11496.8 KEG09134.1 - 0.052 12.7 0.0 0.2 10.8 0.0 2.0 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 OGG_N PF07934.12 KEG09135.1 - 5e-25 87.9 0.0 9.1e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KEG09135.1 - 1.6e-10 41.4 0.0 4.8e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEG09135.1 - 7.5e-05 22.4 0.1 0.00028 20.6 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif CHASE6_C PF17150.4 KEG09136.1 - 0.15 12.8 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Pkinase PF00069.25 KEG09137.1 - 1.9e-41 142.2 0.0 1.5e-28 99.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09137.1 - 1.8e-25 89.8 0.0 1.6e-20 73.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.20 KEG09137.1 - 8.4e-24 83.9 0.0 1.7e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 KEG09137.1 - 1.2e-11 44.1 6.5 5.2e-08 32.5 3.1 3.6 1 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KEG09137.1 - 4.2e-06 27.0 7.5 0.00054 20.3 2.2 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 KEG09137.1 - 6.6e-06 25.6 0.0 0.039 13.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KEG09137.1 - 0.012 14.6 0.1 0.023 13.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain LRR_9 PF14580.6 KEG09137.1 - 0.016 14.7 0.7 0.11 12.0 0.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeat Y_phosphatase PF00102.27 KEG09137.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LRR_1 PF00560.33 KEG09137.1 - 1.4 9.8 4.7 26 5.9 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4763 PF15960.5 KEG09138.1 - 1.9 7.7 8.3 2.7 7.2 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Pinin_SDK_N PF04697.13 KEG09139.1 - 0.014 16.0 4.7 0.038 14.6 4.7 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region F-protein PF00469.20 KEG09139.1 - 1.9 8.0 4.5 3.5 7.2 4.5 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef GDI PF00996.18 KEG09140.1 - 1.5e-19 69.8 0.0 4.6e-06 25.4 0.0 3.1 3 0 0 3 3 3 3 GDP dissociation inhibitor Methyltransf_16 PF10294.9 KEG09140.1 - 1.3e-12 47.8 0.0 1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase NNMT_PNMT_TEMT PF01234.17 KEG09140.1 - 0.0031 16.8 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family PrmA PF06325.13 KEG09140.1 - 0.2 11.0 0.0 0.45 9.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DPM2 PF07297.12 KEG09141.1 - 4.1e-15 55.8 1.2 4.9e-15 55.6 1.2 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 7tm_7 PF08395.12 KEG09141.1 - 0.053 12.7 0.1 0.059 12.6 0.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Pex16 PF08610.10 KEG09142.1 - 3.1e-16 59.4 0.1 9.3e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) SlyX PF04102.12 KEG09143.1 - 0.048 14.3 0.4 0.048 14.3 0.4 7.2 6 1 0 6 6 6 0 SlyX IATP PF04568.12 KEG09143.1 - 0.078 13.4 0.0 0.078 13.4 0.0 4.0 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP TSC22 PF01166.18 KEG09143.1 - 2.5 8.5 11.8 7.2 7.0 0.2 4.7 5 0 0 5 5 5 0 TSC-22/dip/bun family WW PF00397.26 KEG09144.1 - 1.2e-15 57.3 2.5 3e-08 33.6 0.5 2.4 2 0 0 2 2 2 2 WW domain Focal_AT PF03623.13 KEG09146.1 - 0.21 11.6 3.5 0.12 12.3 0.7 1.9 2 0 0 2 2 2 0 Focal adhesion targeting region Coatomer_WDAD PF04053.14 KEG09147.1 - 1.9e-142 475.4 0.0 3.7e-142 474.5 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KEG09147.1 - 7.1e-27 93.1 1.2 5.3e-07 30.2 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG09147.1 - 5.9e-07 29.7 0.0 1.9 8.9 0.0 5.5 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-RanBP PF00641.18 KEG09148.1 - 3.3e-27 93.5 47.7 7e-08 31.7 0.9 6.4 6 0 0 6 6 6 6 Zn-finger in Ran binding protein and others DZR PF12773.7 KEG09148.1 - 0.056 13.5 40.4 0.11 12.5 6.8 5.0 2 2 1 4 4 4 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KEG09148.1 - 7.1 6.4 16.9 4.5 7.1 0.9 5.1 5 0 0 5 5 5 0 Predicted integral membrane zinc-ribbon metal-binding protein EF-hand_7 PF13499.6 KEG09149.1 - 2.7e-05 24.5 0.4 0.0036 17.7 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG09149.1 - 0.00038 20.1 0.0 0.01 15.7 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KEG09149.1 - 0.0019 17.6 0.0 0.0059 16.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KEG09149.1 - 0.011 15.2 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_13 PF17958.1 KEG09149.1 - 0.091 12.6 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain TT_ORF2 PF02957.15 KEG09150.1 - 7.6 7.5 10.2 4 8.4 8.7 1.3 1 1 0 1 1 1 0 TT viral ORF2 Herpes_UL6 PF01763.16 KEG09151.1 - 0.21 10.1 5.0 0.08 11.5 2.3 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like ApbA_C PF08546.11 KEG09151.1 - 0.34 11.1 1.4 0.36 11.1 0.3 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal YabA PF06156.13 KEG09151.1 - 0.96 10.1 9.4 4.7 7.9 1.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 KEG09151.1 - 6.9 6.8 12.1 6.5 6.9 2.3 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 KEG09151.1 - 8.9 6.6 13.2 6 7.2 3.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) A_deaminase PF00962.22 KEG09152.1 - 1.4e-98 330.2 0.0 2.2e-69 234.3 0.0 2.5 2 0 0 2 2 2 2 Adenosine/AMP deaminase FTA4 PF13093.6 KEG09152.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PIG-S PF10510.9 KEG09153.1 - 0.068 12.0 0.3 0.13 11.0 0.3 1.5 1 1 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein SUIM_assoc PF16619.5 KEG09155.1 - 4 7.6 6.2 1.1 9.4 0.1 3.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 EpmC PF04315.12 KEG09157.1 - 0.01 15.6 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 Elongation factor P hydroxylase DUF5314 PF17241.2 KEG09158.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Dynein_attach_N PF15867.5 KEG09158.1 - 0.17 11.9 0.1 1.3 9.1 0.0 2.3 3 0 0 3 3 3 0 Dynein attachment factor N-terminus NOB1_Zn_bind PF08772.11 KEG09159.1 - 1.3e-24 86.2 0.2 2.3e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KEG09159.1 - 1.1e-23 83.6 0.2 1.7e-23 82.9 0.2 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease DZR PF12773.7 KEG09159.1 - 0.089 12.8 0.5 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon DNA_pol_phi PF04931.13 KEG09159.1 - 4.7 5.2 7.4 6.8 4.7 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hexapep PF00132.24 KEG09161.1 - 1.8e-08 33.7 13.2 0.01 15.5 0.2 5.4 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Exonuc_VII_L PF02601.15 KEG09162.1 - 0.00033 20.3 16.7 0.00033 20.3 16.7 3.4 1 1 2 3 3 3 1 Exonuclease VII, large subunit DUF4795 PF16043.5 KEG09162.1 - 0.013 15.1 28.9 0.14 11.7 15.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SWIRM-assoc_3 PF16498.5 KEG09162.1 - 0.045 14.0 1.0 0.33 11.2 0.0 2.7 3 0 0 3 3 3 0 SWIRM-associated domain at the C-terminal WXG100 PF06013.12 KEG09162.1 - 0.051 13.8 30.9 0.1 12.8 0.8 7.2 4 2 3 7 7 7 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 KEG09162.1 - 0.071 13.3 24.8 0.55 10.4 9.8 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KEG09162.1 - 0.1 12.6 27.4 0.19 11.8 1.7 4.7 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KEG09162.1 - 0.12 12.4 16.7 3.8 7.6 3.4 5.0 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec3_C_2 PF15278.6 KEG09162.1 - 0.43 10.9 4.0 3.2 8.1 0.0 3.7 2 1 1 3 3 3 0 Sec3 exocyst complex subunit HTH_20 PF12840.7 KEG09162.1 - 0.45 10.6 0.1 0.45 10.6 0.1 3.7 5 0 0 5 5 4 0 Helix-turn-helix domain MRP-L46 PF11788.8 KEG09162.1 - 0.58 10.9 19.8 0.077 13.7 14.0 2.5 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 MitMem_reg PF13012.6 KEG09162.1 - 0.59 10.6 10.9 0.92 10.0 2.2 3.8 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function TACC_C PF05010.14 KEG09162.1 - 0.61 9.8 28.1 0.42 10.4 0.5 3.4 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DASH_Dam1 PF08653.10 KEG09162.1 - 0.67 9.8 6.8 1e+02 2.8 0.0 5.3 6 0 0 6 6 5 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 KEG09162.1 - 1.5 9.3 21.4 7.7 7.1 0.2 6.1 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 KEG09162.1 - 1.5 9.2 42.3 2.2 8.7 16.9 4.0 1 1 3 4 4 4 0 Fez1 Baculo_p24 PF05073.12 KEG09162.1 - 1.7 8.4 16.7 1.2 8.9 4.2 3.4 2 1 1 3 3 3 0 Baculovirus P24 capsid protein Apolipoprotein PF01442.18 KEG09162.1 - 1.7 8.5 56.9 15 5.4 38.7 3.2 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain FMN_bind_2 PF04299.12 KEG09162.1 - 2.8 7.6 7.4 1.1 9.0 0.5 3.1 2 1 0 3 3 3 0 Putative FMN-binding domain OmpH PF03938.14 KEG09162.1 - 5.2 7.4 36.4 6.5 7.1 2.6 4.3 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) DUF489 PF04356.12 KEG09162.1 - 7.1 6.6 19.1 0.69 9.9 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF489) Mucin PF01456.17 KEG09164.1 - 4.8e-07 29.9 16.0 6.2e-05 23.0 5.7 4.0 3 2 0 3 3 3 2 Mucin-like glycoprotein DUF2570 PF10828.8 KEG09164.1 - 0.032 14.0 0.3 0.032 14.0 0.3 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2570) ATP-cone PF03477.16 KEG09164.1 - 0.96 10.1 0.0 0.96 10.1 0.0 3.0 3 0 0 3 3 3 0 ATP cone domain GvpL_GvpF PF06386.11 KEG09164.1 - 6.3 6.7 22.0 0.091 12.7 5.0 3.1 3 0 0 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF Nucleo_P87 PF07267.11 KEG09165.1 - 4.6 6.0 7.6 5.3 5.8 7.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1917 PF08939.10 KEG09167.1 - 0.00051 20.0 1.8 0.00051 20.0 1.8 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1917) DUF3614 PF12267.8 KEG09167.1 - 3.1 8.3 6.8 1.7 9.1 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) TSNAXIP1_N PF15739.5 KEG09167.1 - 4.3 7.8 12.6 0.42 11.0 0.7 2.9 3 1 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Mucin PF01456.17 KEG09168.1 - 0.00022 21.3 0.5 0.00022 21.3 0.5 4.5 4 1 0 4 4 4 2 Mucin-like glycoprotein MTBP_C PF14920.6 KEG09169.1 - 0.047 13.4 1.0 0.065 13.0 1.0 1.2 1 0 0 1 1 1 0 MDM2-binding Mucin PF01456.17 KEG09171.1 - 1.4e-07 31.6 26.6 0.0059 16.6 0.2 3.3 2 1 0 2 2 2 2 Mucin-like glycoprotein IFP_35_N PF07334.13 KEG09171.1 - 0.045 13.8 0.7 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Kinesin PF00225.23 KEG09172.1 - 3e-105 351.8 0.2 3e-105 351.8 0.2 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG09172.1 - 1.5e-46 158.0 0.0 5.4e-46 156.2 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding VHS PF00790.19 KEG09172.1 - 2.7e-08 33.8 1.8 7e-08 32.4 0.1 2.7 3 0 0 3 3 3 1 VHS domain RAP1 PF07218.11 KEG09172.1 - 0.0044 15.4 0.1 0.0074 14.6 0.1 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) KxDL PF10241.9 KEG09172.1 - 0.43 10.9 8.3 32 4.9 6.6 3.4 2 0 0 2 2 2 0 Uncharacterized conserved protein GAT PF03127.14 KEG09172.1 - 0.85 10.0 11.4 0.62 10.4 0.4 3.7 3 0 0 3 3 3 0 GAT domain Tup_N PF08581.10 KEG09172.1 - 5 7.5 20.0 1.9 8.8 5.3 4.4 4 0 0 4 4 4 0 Tup N-terminal DUF4407 PF14362.6 KEG09172.1 - 5.7 6.2 13.2 2.7 7.3 6.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UVR PF02151.19 KEG09173.1 - 5.5e-06 25.9 12.9 0.0015 18.2 3.8 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.12 KEG09173.1 - 1.4e-05 25.3 14.2 0.00042 20.5 3.6 3.2 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding CLASP_N PF12348.8 KEG09173.1 - 0.00046 19.8 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KEG09173.1 - 0.078 13.3 5.7 5 7.7 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat zf-C2H2_6 PF13912.6 KEG09173.1 - 0.094 12.7 0.2 2.5 8.2 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger PIEZO PF15917.5 KEG09173.1 - 0.12 11.8 0.8 0.22 11.0 0.8 1.3 1 0 0 1 1 1 0 Piezo Prok-RING_4 PF14447.6 KEG09173.1 - 0.46 10.4 11.9 0.27 11.1 0.6 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.6 KEG09173.1 - 0.75 10.8 11.0 41 5.4 0.0 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger GN3L_Grn1 PF08701.11 KEG09174.1 - 6.8e-06 26.1 14.0 6.8e-06 26.1 14.0 2.5 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase TFIIA PF03153.13 KEG09174.1 - 0.0029 17.7 3.0 0.0029 17.7 3.0 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Complex1_LYR PF05347.15 KEG09175.1 - 9.2e-07 28.8 1.3 5e-06 26.5 0.0 3.0 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEG09175.1 - 0.021 15.6 0.1 0.021 15.6 0.1 2.9 3 0 0 3 3 3 0 Complex1_LYR-like ASH PF15780.5 KEG09176.1 - 5.4e-06 26.5 0.1 3.8 7.8 0.0 6.5 7 0 0 7 7 7 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 KEG09176.1 - 0.055 13.5 0.0 42 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) PapD_N PF00345.20 KEG09176.1 - 0.099 12.6 2.8 0.38 10.7 0.0 3.3 3 0 0 3 3 3 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Suf PF05843.14 KEG09176.1 - 5.8 6.8 11.5 0.073 13.0 0.3 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) EF-hand_7 PF13499.6 KEG09177.1 - 0.00021 21.7 0.0 0.00042 20.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG09177.1 - 0.00061 19.5 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KEG09177.1 - 0.0046 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 EF hand Cwf_Cwc_15 PF04889.12 KEG09177.1 - 0.028 14.2 1.8 0.048 13.4 1.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Roughex PF06020.11 KEG09177.1 - 0.066 12.3 2.8 0.13 11.4 2.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein PBP1_TM PF14812.6 KEG09177.1 - 5.7 7.4 8.1 13 6.2 8.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RHD3 PF05879.12 KEG09179.1 - 1.1e-102 344.5 0.6 4.9e-92 309.3 0.0 2.9 2 1 0 3 3 3 2 Root hair defective 3 GTP-binding protein (RHD3) AAA_28 PF13521.6 KEG09179.1 - 3.7e-05 24.0 0.1 0.00013 22.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KEG09179.1 - 0.00037 20.6 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KEG09179.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG09179.1 - 0.0067 16.8 2.1 0.016 15.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KEG09179.1 - 0.092 13.3 0.0 0.41 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Mago-bind PF09282.10 KEG09179.1 - 2.4 8.1 3.5 1.3 8.9 0.6 2.1 2 0 0 2 2 2 0 Mago binding HILPDA PF15220.6 KEG09181.1 - 0.037 14.1 0.0 0.037 14.1 0.0 2.4 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated Ninjurin PF04923.12 KEG09181.1 - 0.79 9.7 10.7 2.8 7.9 4.1 2.7 2 0 0 2 2 2 0 Ninjurin JAB PF01398.21 KEG09182.1 - 4.3e-20 71.8 0.0 2.4e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KEG09182.1 - 3.9e-19 69.1 0.8 1e-18 67.8 0.5 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function TAN PF11640.8 KEG09182.1 - 0.0044 17.1 0.3 0.0044 17.1 0.3 2.0 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Mt_ATP-synt_B PF05405.14 KEG09182.1 - 0.04 13.5 0.8 0.083 12.5 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1664 PF07889.12 KEG09182.1 - 0.076 13.1 1.3 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MscS_TM PF12794.7 KEG09182.1 - 0.44 9.3 1.2 0.68 8.7 1.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3938 PF13074.6 KEG09183.1 - 0.024 14.9 1.4 0.024 14.9 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF2569 PF10754.9 KEG09183.1 - 6.1 7.3 18.1 3.6 8.0 12.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) FdhE PF04216.12 KEG09184.1 - 0.036 13.9 7.3 0.083 12.8 7.3 1.6 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Sec5 PF15469.6 KEG09184.1 - 0.063 13.1 6.7 0.075 12.8 5.1 1.9 1 1 1 2 2 2 0 Exocyst complex component Sec5 Imm5 PF14423.6 KEG09184.1 - 0.076 13.2 0.2 0.076 13.2 0.2 1.8 2 0 0 2 2 2 0 Immunity protein Imm5 KIP1 PF07765.12 KEG09184.1 - 1.6 8.9 5.3 2.5 8.3 3.0 2.6 1 1 1 2 2 2 0 KIP1-like protein DUF719 PF05334.13 KEG09185.1 - 5.5 7.1 9.4 9 6.5 3.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DCX PF03607.17 KEG09187.1 - 0.039 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Doublecortin Aldo_ket_red PF00248.21 KEG09188.1 - 1.2e-57 195.3 0.0 1.2e-55 188.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DNA_pol_A PF00476.20 KEG09189.1 - 1.5e-35 123.0 0.0 3.2e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.24 KEG09189.1 - 1e-19 71.7 0.0 1.8e-18 67.6 0.0 2.6 3 0 0 3 3 3 1 Exonuclease ASH PF15780.5 KEG09190.1 - 8.9e-21 73.9 13.6 0.014 15.5 0.2 12.1 13 1 0 13 13 13 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KEG09190.1 - 1.7e-08 34.3 0.1 1 9.3 0.2 6.9 8 0 0 8 8 8 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 KEG09190.1 - 0.0082 16.2 0.6 5.5 7.1 0.0 5.6 8 0 0 8 8 8 1 Protein of unknown function (DUF1573) DUF5001 PF16392.5 KEG09190.1 - 0.032 14.1 0.5 0.4 10.6 0.1 3.1 3 0 0 3 3 3 0 Ig-like domain DUF3122 PF11320.8 KEG09191.1 - 0.046 13.8 0.5 5.9 7.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3122) NYD-SP28_assoc PF14775.6 KEG09193.1 - 0.16 12.1 0.5 0.26 11.4 0.5 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain Gpr1_Fun34_YaaH PF01184.19 KEG09195.1 - 0.029 14.0 0.2 0.035 13.7 0.2 1.1 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family TPR_2 PF07719.17 KEG09196.1 - 1.5e-11 43.5 14.0 0.01 15.9 0.0 9.3 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09196.1 - 2.4e-08 33.4 11.6 0.012 15.4 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG09196.1 - 8.2e-08 32.3 12.7 0.01 15.9 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09196.1 - 3.8e-07 30.5 7.2 0.27 11.8 0.4 6.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG09196.1 - 4e-06 26.5 7.9 0.04 13.9 0.0 6.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09196.1 - 1.6e-05 25.1 9.8 0.12 12.7 0.0 6.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG09196.1 - 1.7e-05 25.2 17.1 4.2 8.4 0.1 8.1 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG09196.1 - 2.1e-05 24.4 4.2 0.084 13.1 0.0 5.9 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG09196.1 - 3.1e-05 24.5 6.6 7.9 7.2 0.2 6.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KEG09196.1 - 0.0037 17.6 0.7 1.6 9.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09196.1 - 0.0063 16.2 0.0 4.7 7.0 0.0 4.3 5 0 0 5 5 5 1 TPR repeat KfrA_N PF11740.8 KEG09196.1 - 0.0086 16.7 0.2 0.033 14.9 0.2 1.9 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term TPR_17 PF13431.6 KEG09196.1 - 0.016 15.6 0.9 10 6.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG09196.1 - 0.023 14.9 11.9 1.6 9.0 0.3 5.7 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KEG09196.1 - 0.03 13.3 0.2 0.55 9.1 0.4 2.2 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 FAT PF02259.23 KEG09196.1 - 0.056 12.7 0.1 4.8 6.3 0.1 2.3 2 0 0 2 2 2 0 FAT domain TPR_10 PF13374.6 KEG09196.1 - 0.97 9.4 9.3 0.66 9.9 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat XRN_N PF03159.18 KEG09197.1 - 3.6e-87 291.8 0.1 8.7e-87 290.6 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KEG09197.1 - 2e-64 218.2 0.5 2e-64 218.2 0.5 2.6 1 1 0 2 2 2 1 Xrn1 helical domain AAA_11 PF13086.6 KEG09198.1 - 2.7 7.7 6.2 3.6 7.3 6.2 1.2 1 0 0 1 1 1 0 AAA domain MORN PF02493.20 KEG09199.1 - 8.4e-61 198.4 110.5 8.6e-08 31.6 1.1 20.4 21 3 0 21 21 21 16 MORN repeat DUF3994 PF13159.6 KEG09199.1 - 5.6 7.6 6.9 1.3 9.7 0.2 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3994) DUF3048_C PF17479.2 KEG09199.1 - 8.5 6.8 22.8 1.1 9.7 0.2 6.8 3 2 2 7 7 7 0 Protein of unknown function (DUF3048) C-terminal domain HTH_38 PF13936.6 KEG09200.1 - 0.00011 21.8 0.2 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KEG09200.1 - 0.094 12.5 0.3 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Sirohm_synth_C PF14823.6 KEG09201.1 - 0.78 9.4 6.3 1.4 8.6 0.8 2.8 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal TFIIA PF03153.13 KEG09201.1 - 3.2 7.7 10.6 5.1 7.0 10.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 KEG09202.1 - 7e-07 29.5 0.0 0.0016 18.7 0.0 3.0 3 0 0 3 3 3 2 C2 domain DUF2382 PF09557.10 KEG09202.1 - 0.033 14.4 0.2 0.099 12.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) Ribosomal_S13_N PF08069.12 KEG09202.1 - 0.55 10.3 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KEG09203.1 - 1.1e-09 38.7 0.0 1.8e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0029 PF01205.19 KEG09204.1 - 2.2e-31 108.3 0.6 5.3e-31 107.1 0.0 1.8 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KEG09204.1 - 5e-05 23.6 0.0 0.00041 20.6 0.0 2.2 1 1 0 1 1 1 1 RWD domain Galactosyl_T PF01762.21 KEG09206.1 - 3.2e-05 23.9 0.0 0.0038 17.1 0.0 3.1 3 1 0 3 3 3 1 Galactosyltransferase DUF1380 PF07128.12 KEG09206.1 - 0.16 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Galactosyl_T PF01762.21 KEG09207.1 - 1.4e-08 34.8 0.3 0.0056 16.5 0.0 3.4 3 1 0 4 4 4 3 Galactosyltransferase Galactosyl_T PF01762.21 KEG09208.1 - 4.8e-05 23.3 0.0 0.014 15.2 0.0 3.3 3 1 0 3 3 3 1 Galactosyltransferase Peptidase_C2 PF00648.21 KEG09209.1 - 9.5e-37 126.6 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG09209.1 - 3.8e-23 81.8 0.1 7.1e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) KdgM PF06178.13 KEG09210.1 - 0.095 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) Fe-ADH PF00465.19 KEG09212.1 - 8.2e-123 409.8 3.7 9.2e-123 409.6 3.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KEG09212.1 - 5.6e-20 72.1 2.0 2.6e-09 37.1 2.6 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Lamprin PF06403.11 KEG09212.1 - 0.036 14.0 1.3 0.092 12.7 0.5 2.1 2 0 0 2 2 2 0 Lamprin GTP_EFTU PF00009.27 KEG09213.1 - 2.7e-55 186.9 0.1 5e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEG09213.1 - 1.1e-19 70.8 0.0 1.4e-18 67.3 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEG09213.1 - 1.2e-07 32.0 0.4 2.8e-07 30.8 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEG09213.1 - 0.0012 18.9 0.1 0.0046 17.0 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Tctex-1 PF03645.13 KEG09214.1 - 6e-20 71.4 0.2 8.2e-20 71.0 0.2 1.2 1 0 0 1 1 1 1 Tctex-1 family CDC45 PF02724.14 KEG09215.1 - 0.12 10.7 1.2 0.17 10.2 1.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_11 PF08241.12 KEG09216.1 - 1.9e-21 76.5 0.1 1.4e-10 41.6 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 KEG09216.1 - 1.5e-18 67.3 0.1 2.2e-08 34.7 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KEG09216.1 - 1.6e-13 50.7 0.0 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KEG09216.1 - 4.5e-12 46.1 0.0 1.3e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 KEG09216.1 - 2.5e-09 36.8 0.2 8.2e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KEG09216.1 - 1.9e-08 35.0 0.0 0.0042 17.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain DOT1 PF08123.13 KEG09216.1 - 7.6e-08 32.1 0.0 0.00065 19.3 0.0 2.2 2 0 0 2 2 2 2 Histone methylation protein DOT1 Ubie_methyltran PF01209.18 KEG09216.1 - 7.4e-06 25.5 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KEG09216.1 - 9.5e-06 25.5 0.0 0.0007 19.4 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KEG09216.1 - 1.2e-05 24.9 0.0 0.055 13.1 0.0 2.2 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KEG09216.1 - 1.7e-05 24.9 0.1 0.086 12.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain DUF1496 PF07383.12 KEG09216.1 - 0.1 12.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1496) DUF870 PF05912.11 KEG09216.1 - 0.15 12.1 0.3 24 5.0 0.0 2.8 3 0 0 3 3 3 0 Caenorhabditis elegans protein of unknown function (DUF870) UQ_con PF00179.26 KEG09217.1 - 5.3e-41 139.5 0.0 6e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEG09217.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B TMEM154 PF15102.6 KEG09218.1 - 0.23 11.3 0.3 0.59 10.0 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family S1FA PF04689.13 KEG09218.1 - 0.7 10.1 2.2 1.7 8.9 2.2 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Syndecan PF01034.20 KEG09218.1 - 1.3 9.0 4.3 2.5 8.1 4.3 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KEG09218.1 - 8.8 6.2 9.8 0.29 10.9 3.4 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Amastin PF07344.11 KEG09219.1 - 8.1e-17 61.5 10.1 1.1e-16 61.0 10.1 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF3810 PF12725.7 KEG09219.1 - 0.086 12.2 3.5 0.15 11.4 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2254 PF10011.9 KEG09219.1 - 0.13 11.1 7.0 0.92 8.3 2.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF4149 PF13664.6 KEG09219.1 - 7 7.0 13.7 0.045 14.1 3.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF2631 PF10939.8 KEG09219.1 - 8.7 6.3 6.5 4.6 7.2 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2631) RRM_1 PF00076.22 KEG09220.1 - 2.1e-19 69.1 0.1 3.3e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09220.1 - 0.095 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KEG09221.1 - 9.4e-18 63.8 0.0 2.4e-17 62.5 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09221.1 - 1.1e-05 25.0 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG09221.1 - 0.076 13.1 0.0 0.099 12.8 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 KEG09222.1 - 4.8e-17 61.5 0.0 1.1e-16 60.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09222.1 - 2.7e-05 23.8 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG09222.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif His_Me_b4a2 PF18275.1 KEG09226.1 - 0.19 11.9 2.0 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain DUF5082 PF16888.5 KEG09226.1 - 0.19 12.0 0.0 0.25 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) LRR_4 PF12799.7 KEG09228.1 - 4.1e-23 81.1 0.3 0.0019 18.6 0.0 7.4 2 2 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG09228.1 - 1.8e-16 59.7 0.8 0.013 15.3 0.0 5.8 3 2 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 KEG09228.1 - 2.2e-13 49.1 8.8 0.22 11.7 0.0 10.0 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.33 KEG09228.1 - 1.4e-06 28.0 9.3 69 4.6 0.0 9.9 11 2 0 11 11 11 0 Leucine Rich Repeat NP1-WLL PF11733.8 KEG09228.1 - 0.032 14.0 0.0 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Non-capsid protein NP1 UPF0731 PF14982.6 KEG09228.1 - 0.16 12.2 1.1 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 UPF0731 family LRR_4 PF12799.7 KEG09229.1 - 5.2e-10 39.4 8.2 0.13 12.7 0.0 5.4 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG09229.1 - 2.6e-09 36.4 11.2 0.015 15.3 0.1 6.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 KEG09229.1 - 2.5e-06 27.1 10.2 0.039 13.7 1.3 4.6 3 3 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KEG09229.1 - 0.16 11.5 1.6 10 5.6 0.0 2.8 1 1 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KEG09229.1 - 0.89 10.4 11.1 1.2e+02 3.8 0.2 6.3 5 2 0 5 5 5 0 Leucine Rich Repeat Mucin PF01456.17 KEG09232.1 - 3.1e-08 33.7 22.9 0.00015 21.7 16.3 2.8 2 1 0 2 2 2 2 Mucin-like glycoprotein RNA_pol_Rpa2_4 PF06883.12 KEG09232.1 - 0.0053 16.7 1.1 0.16 12.0 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain Totivirus_coat PF05518.11 KEG09232.1 - 9 4.2 7.5 11 3.9 7.5 1.3 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_M8 PF01457.16 KEG09233.1 - 4.3e-11 42.2 0.7 5.7e-11 41.8 0.7 1.1 1 0 0 1 1 1 1 Leishmanolysin Mucin PF01456.17 KEG09233.1 - 4.1e-06 26.8 1.1 5.2e-06 26.5 1.1 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein TMEM154 PF15102.6 KEG09233.1 - 0.22 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_M8 PF01457.16 KEG09234.1 - 3.5e-27 95.3 0.0 4.8e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF4131 PF13567.6 KEG09234.1 - 0.012 15.2 3.9 0.29 10.8 3.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2157 PF09925.9 KEG09234.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PPR PF01535.20 KEG09235.1 - 0.0051 17.0 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.6 KEG09235.1 - 0.043 14.0 0.0 0.65 10.2 0.0 2.0 1 1 1 2 2 2 0 PPR repeat family C2-C2_1 PF11618.8 KEG09237.1 - 3.4e-26 92.0 0.3 3.4e-26 92.0 0.3 2.4 2 1 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 ATG16 PF08614.11 KEG09237.1 - 0.011 16.0 5.2 0.011 16.0 5.2 6.8 4 1 3 7 7 7 0 Autophagy protein 16 (ATG16) Spt20 PF12090.8 KEG09237.1 - 3.2 7.3 10.6 0.46 10.0 6.0 1.9 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.9 KEG09238.1 - 2.7 7.6 8.5 5.9 6.4 8.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RICTOR_M PF14666.6 KEG09239.1 - 8.8e-23 80.1 2.1 5.6e-21 74.3 0.4 3.7 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 KEG09239.1 - 1.5e-17 63.6 5.9 7.4e-14 51.5 0.1 3.0 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KEG09239.1 - 1.3e-14 54.5 2.8 8.4e-13 48.7 0.2 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KEG09239.1 - 4.8e-10 39.5 1.4 8.9e-08 32.3 0.2 3.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF PF00617.19 KEG09240.1 - 2.3e-27 96.4 0.0 3.2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEG09240.1 - 1.1e-15 57.7 0.1 2.3e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif PP1 PF07430.11 KEG09240.1 - 0.039 14.0 0.4 0.53 10.4 0.0 2.7 3 0 0 3 3 3 0 Phloem filament protein PP1 cystatin-like domain ABC_membrane PF00664.23 KEG09241.1 - 1.2e-51 176.0 1.5 1.7e-51 175.5 1.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEG09241.1 - 1e-30 107.0 0.0 1.9e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEG09241.1 - 0.0003 20.3 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KEG09241.1 - 0.0016 18.9 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG09241.1 - 0.0022 18.3 0.1 0.46 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KEG09241.1 - 0.0071 16.1 0.0 0.058 13.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KEG09241.1 - 0.014 15.8 0.1 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 KEG09241.1 - 0.018 13.9 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF87 PF01935.17 KEG09241.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KEG09241.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEG09241.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RRM_1 PF00076.22 KEG09242.1 - 5.6e-18 64.5 0.0 9.3e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09242.1 - 0.00059 19.4 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.8 KEG09242.1 - 0.032 13.0 3.4 0.036 12.9 3.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRM_1 PF00076.22 KEG09244.1 - 2.1e-21 75.5 0.0 3.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09244.1 - 0.0012 18.4 1.3 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG09244.1 - 0.0084 16.0 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif Presenilin PF01080.17 KEG09244.1 - 0.18 10.6 2.0 0.15 10.8 2.0 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KEG09244.1 - 0.23 11.5 2.5 0.25 11.4 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CorA PF01544.18 KEG09249.1 - 4.2e-14 52.5 2.7 1.4e-07 31.1 0.9 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Peptidase_M20 PF01546.28 KEG09250.1 - 1.8e-35 122.5 0.2 2.3e-35 122.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEG09250.1 - 1.4e-20 73.2 0.0 2.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 KEG09250.1 - 0.00012 21.2 0.1 0.015 14.3 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KEG09250.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Tctex-1 PF03645.13 KEG09251.1 - 2.5e-22 79.0 0.1 2.9e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family PNPase PF03726.14 KEG09251.1 - 0.081 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PG_binding_2 PF08823.11 KEG09251.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Ribosomal_S11 PF00411.19 KEG09252.1 - 1.3e-47 160.8 1.0 1.6e-47 160.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Vps39_2 PF10367.9 KEG09255.1 - 1.7e-25 89.6 1.8 3.2e-25 88.7 1.8 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KEG09255.1 - 0.01 15.7 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Region in Clathrin and VPS EccE PF11203.8 KEG09257.1 - 0.005 17.1 0.1 0.04 14.2 0.0 2.5 2 0 0 2 2 2 1 Putative type VII ESX secretion system translocon, EccE RseA_C PF03873.13 KEG09258.1 - 0.077 13.2 0.0 0.077 13.2 0.0 2.5 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Malic_M PF03949.15 KEG09260.1 - 4.5e-87 291.6 0.2 5.9e-87 291.2 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KEG09260.1 - 4.2e-63 212.4 0.0 6.1e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SNF2_N PF00176.23 KEG09261.1 - 1.3e-56 191.8 0.0 2.6e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG09261.1 - 1.5e-18 67.2 0.0 1.2e-17 64.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG09261.1 - 3.1e-09 37.1 0.0 6.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG09261.1 - 2.7e-08 33.8 0.0 4.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 KEG09262.1 - 3.4e-06 26.8 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EccE PF11203.8 KEG09262.1 - 0.066 13.5 0.1 0.37 11.1 0.1 2.1 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE POTRA_2 PF08479.11 KEG09262.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type HAD_SAK_2 PF18143.1 KEG09263.1 - 4.7e-33 114.5 0.0 1e-32 113.4 0.0 1.6 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Macoilin PF09726.9 KEG09263.1 - 0.001 17.7 3.7 0.0013 17.4 3.7 1.1 1 0 0 1 1 1 1 Macoilin family TMF_DNA_bd PF12329.8 KEG09263.1 - 0.022 14.7 3.0 0.022 14.7 3.0 2.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 KEG09263.1 - 0.037 14.5 9.6 0.21 12.0 9.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB CENP-K PF11802.8 KEG09263.1 - 0.13 11.8 4.4 0.22 11.0 4.4 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Cep57_MT_bd PF06657.13 KEG09263.1 - 0.38 11.2 7.5 5.8 7.5 0.8 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CENP-F_leu_zip PF10473.9 KEG09263.1 - 0.62 10.1 12.2 0.056 13.5 2.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 KEG09263.1 - 0.67 10.6 10.7 0.14 12.7 1.3 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF3585 PF12130.8 KEG09263.1 - 1.3 9.2 13.1 3.1 7.9 13.1 1.5 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain HAUS-augmin3 PF14932.6 KEG09263.1 - 1.9 8.0 9.6 0.29 10.7 4.3 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KEG09263.1 - 6.4 7.5 5.9 79 4.0 5.9 2.2 1 1 0 1 1 1 0 Initiation control protein YabA ATP-synt_10 PF05176.14 KEG09266.1 - 2e-05 24.0 0.0 3.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ATP10 protein AAA_12 PF13087.6 KEG09267.1 - 1.1e-60 204.7 0.0 2.2e-60 203.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 KEG09267.1 - 3.1e-56 189.6 3.4 6.4e-56 188.6 3.4 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 KEG09267.1 - 5.3e-52 177.2 1.6 7.8e-27 94.7 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KEG09267.1 - 8.3e-15 55.0 0.0 3.6e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG09267.1 - 8.9e-13 48.8 0.0 3.1e-12 47.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain UvrD-helicase PF00580.21 KEG09267.1 - 4e-06 26.6 0.0 0.024 14.1 0.0 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KEG09267.1 - 5.9e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KEG09267.1 - 0.00036 20.4 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 Helicase PhoH PF02562.16 KEG09267.1 - 0.0004 19.9 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KEG09267.1 - 0.0045 16.3 0.8 0.029 13.6 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KEG09267.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 KEG09267.1 - 0.024 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG09267.1 - 0.026 14.9 0.0 0.09 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KEG09267.1 - 0.037 13.7 0.1 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PH_TFIIH PF08567.11 KEG09267.1 - 0.041 14.2 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain AAA_22 PF13401.6 KEG09267.1 - 0.044 14.1 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KEG09267.1 - 0.068 12.3 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase RuvB_N PF05496.12 KEG09267.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DBR1 PF05011.13 KEG09268.1 - 1.9e-09 38.1 0.0 4.3e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain PK PF00224.21 KEG09269.1 - 0.13 11.1 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain CD52 PF15116.6 KEG09269.1 - 0.19 11.8 1.4 0.49 10.5 0.1 2.4 2 0 0 2 2 2 0 CAMPATH-1 antigen Glyco_trans_1_2 PF13524.6 KEG09271.1 - 0.17 12.3 3.6 0.37 11.2 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 Antimicrobial10 PF08105.11 KEG09271.1 - 0.24 11.5 1.7 0.81 9.8 1.7 1.9 1 0 0 1 1 1 0 Metchnikowin family Frataxin_Cyay PF01491.16 KEG09272.1 - 6.5e-27 93.7 0.0 8.1e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain MetallophosN PF16371.5 KEG09272.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase Pox_MCEL PF03291.16 KEG09276.1 - 2.6e-12 46.5 0.0 4.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KEG09276.1 - 0.00011 22.8 0.0 0.002 18.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG09276.1 - 0.003 18.3 0.0 0.0085 16.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain mRNA_cap_enzyme PF01331.19 KEG09276.1 - 0.0092 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Methyltransf_32 PF13679.6 KEG09276.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PWI PF01480.17 KEG09276.1 - 0.17 12.3 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 PWI domain OSCP PF00213.18 KEG09276.1 - 0.21 11.7 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit CEBP_ZZ PF16366.5 KEG09276.1 - 6.3 7.1 8.1 30 4.9 0.0 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TPR_1 PF00515.28 KEG09277.1 - 1.3e-20 72.3 19.5 2.4e-06 27.1 2.2 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEG09277.1 - 1.1e-16 59.5 21.2 0.00027 20.8 2.3 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09277.1 - 1.6e-13 50.7 7.6 1.5e-05 25.2 1.1 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09277.1 - 4.6e-10 39.0 19.1 0.0011 18.6 0.7 5.0 2 2 3 5 5 5 3 TPR repeat TPR_16 PF13432.6 KEG09277.1 - 5.9e-10 39.6 13.1 0.00018 22.1 0.9 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG09277.1 - 3.1e-09 36.3 20.8 0.00015 21.7 0.1 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09277.1 - 5.3e-09 36.4 13.9 0.00073 20.0 1.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG09277.1 - 5.4e-09 36.1 11.7 0.0062 17.3 1.5 5.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG09277.1 - 1.2e-08 34.8 11.0 0.0069 16.7 1.2 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG09277.1 - 3.2e-08 33.0 9.9 0.0026 17.7 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG09277.1 - 5.2e-08 33.0 7.1 0.002 18.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 KEG09277.1 - 0.002 18.4 2.3 1.9 8.9 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG09277.1 - 0.016 15.4 2.8 0.016 15.4 2.8 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEG09277.1 - 0.017 15.2 11.3 0.24 11.6 0.4 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG09277.1 - 0.23 11.4 7.0 2.8 7.9 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KEG09279.1 - 1.7e-41 142.3 0.0 2.2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09279.1 - 6.5e-21 74.8 0.1 6.4e-20 71.5 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG09279.1 - 4.2e-06 25.8 0.0 6.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG09279.1 - 0.0056 16.1 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEG09279.1 - 0.074 12.6 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CRM1_repeat_2 PF18784.1 KEG09279.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 AA_permease_2 PF13520.6 KEG09280.1 - 1.5e-22 80.1 35.7 1.8e-22 79.8 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease Ribonuclease_3 PF00636.26 KEG09281.1 - 0.0033 18.0 0.0 0.012 16.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain AATF-Che1 PF13339.6 KEG09283.1 - 1.2e-09 39.0 3.1 1.2e-09 39.0 3.1 4.2 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 KEG09283.1 - 0.0081 16.7 2.9 0.033 14.7 0.0 3.3 3 1 1 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal Glyco_hydro_67N PF03648.14 KEG09283.1 - 0.15 12.3 0.2 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Drc1-Sld2 PF11719.8 KEG09283.1 - 0.39 10.2 11.7 0.86 9.1 11.7 1.6 1 0 0 1 1 1 0 DNA replication and checkpoint protein Tho2 PF11262.8 KEG09284.1 - 1.4e-05 24.4 0.0 5.7e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 BUD22 PF09073.10 KEG09284.1 - 5.4 6.2 23.3 16 4.7 23.3 1.8 1 0 0 1 1 1 0 BUD22 Proteasome PF00227.26 KEG09286.1 - 2.2e-58 196.9 0.0 2.7e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG09286.1 - 1.6e-14 53.3 0.2 2.6e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rad51 PF08423.11 KEG09287.1 - 3e-18 66.0 0.0 4.9e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KEG09287.1 - 2.3e-12 46.9 1.8 4.7e-12 45.9 1.8 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KEG09287.1 - 4.4e-07 29.5 0.0 1e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KEG09287.1 - 6.9e-07 28.8 0.0 1.4e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 KEG09287.1 - 5e-05 23.6 0.1 0.00018 21.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KEG09287.1 - 0.00013 22.0 0.1 0.00026 20.9 0.1 1.5 1 0 0 1 1 1 1 NACHT domain RecA PF00154.21 KEG09287.1 - 0.0008 19.0 0.1 0.005 16.3 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DEAD PF00270.29 KEG09287.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_28 PF13521.6 KEG09287.1 - 0.031 14.5 0.2 0.031 14.5 0.2 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KEG09287.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pullulanase_N2 PF17967.1 KEG09287.1 - 3.1 8.7 6.9 0.42 11.5 1.3 2.4 3 0 0 3 3 3 0 Pullulanase N2 domain Pterin_4a PF01329.19 KEG09288.1 - 1.5e-28 98.8 0.6 1.7e-28 98.7 0.6 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PA PF02225.22 KEG09289.1 - 4.9e-06 26.5 0.1 6.7e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 PA domain Pyrophosphatase PF00719.19 KEG09290.1 - 1.1e-45 155.4 0.0 1.9e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase UPF0154 PF03672.13 KEG09290.1 - 0.021 14.8 0.5 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_7 PF13499.6 KEG09290.1 - 0.089 13.3 0.0 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair LRR_6 PF13516.6 KEG09292.1 - 1.7e-08 33.9 1.2 0.00019 21.3 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KEG09292.1 - 0.0084 16.5 0.0 0.12 12.9 0.0 2.8 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG09292.1 - 0.022 15.3 0.0 2 9.3 0.0 3.4 3 1 0 3 3 3 0 Leucine Rich Repeat DEAD PF00270.29 KEG09293.1 - 2e-26 92.8 0.0 3.4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG09293.1 - 3.1e-08 33.8 0.0 2.5e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEG09293.1 - 7.4e-06 26.3 0.0 9.3e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 KEG09293.1 - 0.045 13.2 0.1 0.088 12.2 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein VIT1 PF01988.19 KEG09295.1 - 2.6e-54 184.4 3.8 3.3e-54 184.0 3.8 1.1 1 0 0 1 1 1 1 VIT family SET PF00856.28 KEG09296.1 - 0.02 15.3 0.0 0.022 15.2 0.0 1.5 1 1 0 1 1 1 0 SET domain XPG_I PF00867.18 KEG09298.1 - 2.7e-31 107.8 0.0 5.5e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KEG09298.1 - 2.1e-25 89.1 0.0 4e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KEG09298.1 - 8.9e-06 26.2 0.2 6.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 KEG09298.1 - 0.00027 20.9 0.0 0.00047 20.1 0.0 1.4 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain XRN_N PF03159.18 KEG09298.1 - 0.0014 18.1 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Sigma70_r1_1 PF03979.14 KEG09298.1 - 0.033 14.3 1.0 0.11 12.6 1.0 1.9 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 PBP1_TM PF14812.6 KEG09298.1 - 0.055 13.8 0.3 0.096 13.1 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F420_oxidored PF03807.17 KEG09300.1 - 0.19 12.3 1.1 0.94 10.1 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent PDE6_gamma PF04868.12 KEG09300.1 - 5 7.4 8.5 0.49 10.7 0.1 3.0 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit PP-binding PF00550.25 KEG09301.1 - 1.1e-10 41.7 0.1 1.5e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DIM1 PF02966.16 KEG09301.1 - 0.054 13.3 0.1 0.074 12.8 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 FAD-oxidase_C PF02913.19 KEG09302.1 - 6e-45 153.8 0.5 8.8e-45 153.3 0.5 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEG09302.1 - 2.9e-36 124.2 1.2 1.3e-35 122.1 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lact-deh-memb PF09330.11 KEG09302.1 - 0.13 11.6 0.1 0.41 9.9 0.1 1.7 1 1 1 2 2 2 0 D-lactate dehydrogenase, membrane binding Ish1 PF10281.9 KEG09303.1 - 0.00033 20.9 0.3 0.0013 18.9 0.3 2.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP30_Sin3_bdg PF13867.6 KEG09303.1 - 0.082 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 TTL PF03133.15 KEG09304.1 - 1.8e-48 165.2 0.0 5.1e-22 78.4 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 KEG09304.1 - 2.6e-07 30.2 0.0 0.019 14.2 0.0 2.7 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KEG09304.1 - 0.00011 21.5 0.0 0.69 9.1 0.0 2.7 2 1 1 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.11 KEG09304.1 - 0.0013 18.4 0.0 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain SUIM_assoc PF16619.5 KEG09304.1 - 0.032 14.3 0.5 0.064 13.3 0.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ATP-grasp_3 PF02655.14 KEG09304.1 - 0.1 12.6 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain DIOX_N PF14226.6 KEG09305.1 - 2e-28 99.5 0.0 2.4e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEG09306.1 - 1.3e-24 86.6 0.0 2.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIO1 PF01163.22 KEG09307.1 - 8.9e-66 221.1 0.2 2.4e-65 219.7 0.0 1.9 2 0 0 2 2 2 1 RIO1 family TFIIE-A_C PF11521.8 KEG09307.1 - 0.2 12.0 7.9 0.76 10.1 7.9 2.0 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha PIP5K PF01504.18 KEG09308.1 - 5.3e-44 150.5 0.0 6.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Abhydrolase_1 PF00561.20 KEG09308.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1254 PF06863.12 KEG09308.1 - 0.14 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) PIP5K PF01504.18 KEG09309.1 - 4.2e-16 59.0 0.0 4.7e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.32 KEG09311.1 - 3.3e-10 40.4 16.5 0.0046 17.8 0.1 8.2 8 0 0 8 8 8 2 WD domain, G-beta repeat EF-hand_1 PF00036.32 KEG09311.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KEG09311.1 - 0.0021 17.5 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEG09311.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 KEG09311.1 - 0.035 14.0 0.5 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 KEG09311.1 - 0.054 14.0 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Vta1_C PF18097.1 KEG09312.1 - 0.15 11.8 0.0 0.53 10.0 0.0 2.0 1 0 0 1 1 1 0 Vta1 C-terminal domain Metallophos PF00149.28 KEG09313.1 - 1.8e-08 35.2 0.3 2.9e-08 34.5 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Shisa PF13908.6 KEG09314.1 - 0.00059 20.1 1.7 0.00089 19.6 0.0 1.9 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KEG09314.1 - 0.015 16.2 0.8 0.3 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM51 PF15345.6 KEG09314.1 - 0.021 14.7 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 OAD_gamma PF04277.13 KEG09314.1 - 0.036 14.7 0.0 0.077 13.6 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.6 KEG09314.1 - 0.041 14.8 0.4 0.17 12.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Gemini_mov PF01708.16 KEG09314.1 - 0.065 13.0 0.2 0.21 11.4 0.2 1.9 1 1 0 1 1 1 0 Geminivirus putative movement protein Sigma_reg_N PF13800.6 KEG09314.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2448 PF10476.9 KEG09314.1 - 0.14 12.0 0.6 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) CYYR1 PF10873.8 KEG09314.1 - 0.15 12.5 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 ABC2_membrane_3 PF12698.7 KEG09314.1 - 0.32 10.1 2.3 9.9 5.2 0.5 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Prenyltrans PF00432.21 KEG09315.1 - 2.3e-23 81.6 21.4 1.4e-05 24.7 0.7 6.6 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEG09315.1 - 0.069 12.2 0.0 0.51 9.4 0.0 2.2 2 1 1 3 3 3 0 Squalene-hopene cyclase N-terminal domain HalOD1 PF18545.1 KEG09315.1 - 0.44 10.8 2.4 20 5.5 0.2 2.4 1 1 1 2 2 2 0 Halobacterial output domain 1 SeqA_N PF17206.3 KEG09315.1 - 0.48 9.8 1.5 32 4.0 0.1 2.7 2 0 0 2 2 2 0 SeqA protein N-terminal domain COG7 PF10191.9 KEG09316.1 - 6.7e-24 84.2 14.1 7.9e-19 67.4 12.2 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Vps54_N PF10475.9 KEG09316.1 - 0.0069 15.7 6.1 0.019 14.3 6.1 1.7 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF1690 PF07956.11 KEG09316.1 - 0.013 15.9 1.7 0.013 15.9 1.7 3.2 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) Prominin PF05478.11 KEG09316.1 - 0.22 9.4 6.5 0.4 8.6 6.5 1.4 1 0 0 1 1 1 0 Prominin Sec8_exocyst PF04048.14 KEG09316.1 - 0.25 11.2 3.3 0.34 10.8 0.8 2.5 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain YlbD_coat PF14071.6 KEG09316.1 - 0.36 11.1 7.5 0.62 10.3 1.9 2.8 1 1 1 2 2 2 0 Putative coat protein V_ATPase_I PF01496.19 KEG09316.1 - 0.37 8.7 3.4 0.55 8.1 3.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Acyl-CoA_dh_C PF12806.7 KEG09316.1 - 0.48 10.6 4.3 1.2 9.3 0.4 3.8 4 0 0 4 4 3 0 Acetyl-CoA dehydrogenase C-terminal like L1R_F9L PF02442.17 KEG09316.1 - 0.93 9.3 4.8 0.32 10.8 0.5 2.1 1 1 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Vps51 PF08700.11 KEG09316.1 - 1.3 9.2 4.6 9.6 6.4 0.1 3.6 2 1 1 3 3 3 0 Vps51/Vps67 Phasin PF05597.11 KEG09316.1 - 1.3 9.0 9.6 1.3 9.1 0.6 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 KEG09316.1 - 3.5 7.7 14.4 4.1 7.5 1.2 4.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.13 KEG09316.1 - 4.5 7.4 7.0 10 6.3 0.8 3.7 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 KEG09316.1 - 4.5 5.8 8.9 5.2 5.6 7.4 1.7 2 0 0 2 2 2 0 AAA domain ApoO PF09769.9 KEG09316.1 - 4.8 7.2 6.2 3.4 7.6 1.1 3.1 2 1 1 3 3 3 0 Apolipoprotein O DUF1993 PF09351.10 KEG09316.1 - 6.3 6.9 12.3 98 3.0 0.0 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF1993) GLTSCR1 PF15249.6 KEG09320.1 - 0.019 15.4 0.9 0.019 15.4 0.9 3.4 3 1 1 4 4 4 0 Conserved region of unknown function on GLTSCR protein SNCAIP_SNCA_bd PF16700.5 KEG09320.1 - 0.36 10.6 4.8 3.1 7.6 0.0 3.5 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Sad1_UNC PF07738.13 KEG09321.1 - 2.3e-18 66.5 0.0 3.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Macoilin PF09726.9 KEG09321.1 - 0.0017 17.0 6.1 0.0022 16.6 6.1 1.1 1 0 0 1 1 1 1 Macoilin family Snapin_Pallidin PF14712.6 KEG09321.1 - 0.079 13.4 4.1 0.13 12.6 4.1 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Laminin_II PF06009.12 KEG09321.1 - 0.089 12.8 0.3 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain II Tropomyosin PF00261.20 KEG09321.1 - 0.2 11.0 3.7 0.39 10.0 3.7 1.4 1 0 0 1 1 1 0 Tropomyosin AKAP7_RIRII_bdg PF10470.9 KEG09321.1 - 0.2 11.7 1.3 0.44 10.6 1.3 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein KxDL PF10241.9 KEG09321.1 - 0.46 10.8 7.1 2.9 8.2 6.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF4349 PF14257.6 KEG09321.1 - 0.48 9.8 2.3 0.44 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) JIP_LZII PF16471.5 KEG09321.1 - 2.9 8.1 10.8 2.8 8.2 5.5 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 KEG09321.1 - 3.1 8.0 13.2 0.03 14.5 4.2 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) RabGAP-TBC PF00566.18 KEG09322.1 - 6e-08 32.6 0.1 9.2e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 KEG09322.1 - 0.036 14.6 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain Ku_PK_bind PF08785.11 KEG09323.1 - 0.0026 17.9 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Ku C terminal domain like Brix PF04427.18 KEG09324.1 - 1.2e-26 94.1 0.3 1.5e-26 93.7 0.3 1.2 1 0 0 1 1 1 1 Brix domain Clathrin PF00637.20 KEG09325.1 - 1.2e-11 44.7 0.5 3.2e-11 43.3 0.5 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KEG09325.1 - 0.0035 17.1 0.4 0.011 15.6 0.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LysM PF01476.20 KEG09325.1 - 0.012 15.7 0.4 0.034 14.2 0.1 1.9 2 0 0 2 2 2 0 LysM domain zf-RING_2 PF13639.6 KEG09325.1 - 0.013 15.9 0.6 0.013 15.9 0.6 2.4 3 0 0 3 3 3 0 Ring finger domain Vps39_2 PF10367.9 KEG09325.1 - 0.018 15.5 0.0 0.053 14.0 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 KEG09325.1 - 0.018 15.0 0.5 0.049 13.7 0.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KEG09325.1 - 0.11 12.9 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KEG09325.1 - 0.13 11.9 0.4 0.33 10.6 0.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KEG09325.1 - 0.13 12.3 0.1 0.38 10.8 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 KEG09325.1 - 0.61 10.2 3.5 1.7 8.8 3.5 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 KEG09325.1 - 0.85 9.4 3.8 2.1 8.2 3.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger HOOK PF05622.12 KEG09326.1 - 0.00041 18.7 0.0 0.00041 18.7 0.0 3.2 2 1 1 3 3 3 1 HOOK protein Filament PF00038.21 KEG09326.1 - 0.063 12.9 35.5 0.84 9.2 21.0 2.4 1 1 1 2 2 2 0 Intermediate filament protein Takusan PF04822.13 KEG09326.1 - 0.29 11.0 0.1 0.29 11.0 0.1 4.5 4 2 1 5 5 5 0 Takusan RRM_1 PF00076.22 KEG09328.1 - 2.5e-35 120.1 0.0 3.1e-20 71.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09328.1 - 7.9e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEG09328.1 - 2.1e-05 24.4 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KEG09328.1 - 0.0004 20.7 0.3 0.081 13.2 0.1 2.4 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KEG09328.1 - 0.0054 16.8 0.0 0.93 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RNA_bind PF08675.11 KEG09328.1 - 0.078 13.0 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA binding domain RRM_occluded PF16842.5 KEG09328.1 - 0.08 12.8 0.2 1.9 8.4 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif DUF3305 PF11749.8 KEG09329.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) TMEM119 PF15724.5 KEG09330.1 - 0.68 10.0 6.2 1.2 9.2 6.2 1.3 1 0 0 1 1 1 0 TMEM119 family Ras PF00071.22 KEG09331.1 - 1.7e-05 24.4 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SAM_1 PF00536.30 KEG09332.1 - 0.055 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ion_trans_2 PF07885.16 KEG09335.1 - 2.9e-11 43.2 5.7 2.9e-11 43.2 5.7 2.2 2 1 0 2 2 2 1 Ion channel TrkA_C PF02080.21 KEG09335.1 - 0.0085 15.9 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 TrkA-C domain BK_channel_a PF03493.18 KEG09335.1 - 0.066 13.4 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit BDV_P24 PF06595.11 KEG09335.1 - 0.15 12.0 0.1 0.47 10.3 0.1 1.8 2 0 0 2 2 2 0 Borna disease virus P24 protein ABC_tran PF00005.27 KEG09336.1 - 1.5e-16 61.1 0.0 4.3e-16 59.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KEG09336.1 - 7.4e-05 23.2 0.1 7.4e-05 23.2 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KEG09336.1 - 7.4e-05 22.7 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEG09336.1 - 0.00058 20.1 0.1 0.0027 18.0 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KEG09336.1 - 0.0025 17.8 0.3 0.019 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KEG09336.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KEG09336.1 - 0.0079 15.9 0.0 0.0079 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEG09336.1 - 0.014 14.9 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KEG09336.1 - 0.014 15.8 0.1 0.23 11.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEG09336.1 - 0.015 15.6 0.3 0.12 12.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEG09336.1 - 0.021 15.0 1.3 0.4 10.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 KEG09336.1 - 0.022 14.7 0.1 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KEG09336.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEG09336.1 - 0.029 14.9 0.0 0.045 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG09336.1 - 0.032 14.8 0.0 0.088 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEG09336.1 - 0.035 14.2 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEG09336.1 - 0.043 12.9 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 KEG09336.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KEG09336.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.19 KEG09336.1 - 0.1 12.2 0.4 0.74 9.4 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KEG09336.1 - 0.12 12.1 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 KEG09336.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_19 PF13245.6 KEG09336.1 - 0.23 11.8 0.7 0.56 10.5 0.1 1.9 2 0 0 2 2 1 0 AAA domain MRI PF15325.6 KEG09337.1 - 0.11 13.6 0.1 0.27 12.4 0.1 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection CRAL_TRIO PF00650.20 KEG09339.1 - 2.1e-28 99.0 0.0 2.9e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KEG09339.1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEG09339.1 - 0.0058 16.8 0.8 0.015 15.5 0.2 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PH PF00169.29 KEG09340.1 - 5.6e-12 46.1 1.8 5.1e-06 27.0 0.2 2.6 2 1 0 2 2 2 2 PH domain Kelch_4 PF13418.6 KEG09340.1 - 3.5e-09 36.5 5.7 0.00059 19.8 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG09340.1 - 4.4e-05 23.6 3.8 0.72 10.2 0.0 4.9 5 0 0 5 5 5 1 Kelch motif PH_8 PF15409.6 KEG09340.1 - 0.00015 22.0 2.9 0.14 12.4 0.0 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain Kelch_3 PF13415.6 KEG09340.1 - 0.0002 21.5 5.0 0.28 11.5 0.0 4.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG09340.1 - 0.00062 19.7 11.2 0.11 12.5 0.0 5.3 5 1 0 5 5 5 1 Kelch motif PH_11 PF15413.6 KEG09340.1 - 0.01 16.2 5.8 0.08 13.4 0.0 3.1 2 1 1 3 3 3 0 Pleckstrin homology domain Kelch_2 PF07646.15 KEG09340.1 - 0.13 12.3 6.5 11 6.2 1.3 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 KEG09340.1 - 0.26 10.9 18.1 2.4 7.8 5.0 4.6 5 0 0 5 5 5 0 Kelch motif DUF1796 PF08795.10 KEG09341.1 - 2.3e-43 148.1 0.0 3.2e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) DUF2694 PF10904.8 KEG09341.1 - 0.061 13.4 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) Pkinase PF00069.25 KEG09342.1 - 2.2e-31 109.2 0.0 8.9e-12 44.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09342.1 - 5.3e-12 45.6 0.0 6.3e-05 22.4 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase PseudoU_synth_1 PF01416.20 KEG09343.1 - 4.9e-23 81.7 0.0 8.8e-22 77.6 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase Prefoldin_2 PF01920.20 KEG09345.1 - 6.6e-10 38.9 2.8 6.6e-10 38.9 2.8 1.8 2 1 0 2 2 2 1 Prefoldin subunit GAS PF13851.6 KEG09345.1 - 0.022 14.1 0.2 0.022 14.1 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 KEG09345.1 - 0.33 11.2 10.9 0.46 10.8 5.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein ERM PF00769.19 KEG09345.1 - 0.93 9.3 21.8 1.9 8.2 21.8 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4164 PF13747.6 KEG09345.1 - 1.1 9.6 13.8 0.15 12.4 3.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) MMR_HSR1 PF01926.23 KEG09346.1 - 1.2e-08 35.0 0.0 6.2e-06 26.3 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEG09346.1 - 1.1e-05 25.6 0.0 0.0004 20.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 KEG09346.1 - 7.5e-05 22.3 0.4 1.2 8.6 0.1 3.5 4 0 0 4 4 4 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KEG09346.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KEG09346.1 - 0.00045 20.1 0.0 0.0054 16.6 0.0 2.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KEG09346.1 - 0.0018 18.2 0.0 0.073 13.0 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KEG09346.1 - 0.17 11.9 0.0 8.8 6.4 0.0 2.6 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Amastin PF07344.11 KEG09347.1 - 4.9e-40 136.9 10.0 5.9e-40 136.6 10.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1345 PF07077.11 KEG09347.1 - 0.023 14.4 1.3 0.023 14.4 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF2781 PF10914.8 KEG09347.1 - 0.025 15.0 0.8 0.025 15.0 0.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) E1-E2_ATPase PF00122.20 KEG09347.1 - 0.48 9.9 5.6 0.084 12.4 1.8 1.6 2 0 0 2 2 2 0 E1-E2 ATPase AICARFT_IMPCHas PF01808.18 KEG09347.1 - 0.51 9.7 1.9 0.27 10.7 0.1 1.3 2 0 0 2 2 2 0 AICARFT/IMPCHase bienzyme DUF4293 PF14126.6 KEG09347.1 - 0.74 10.1 5.2 4.1 7.6 5.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) TMEM43 PF07787.12 KEG09347.1 - 0.78 9.1 3.7 1.5 8.1 3.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 43 DUF962 PF06127.11 KEG09347.1 - 1.1 9.4 5.5 4.9 7.3 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF4231 PF14015.6 KEG09347.1 - 1.1 9.7 10.4 0.88 10.1 6.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Amastin PF07344.11 KEG09349.1 - 1.1e-34 119.5 6.1 1.4e-34 119.2 6.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein TMEM37 PF15108.6 KEG09349.1 - 0.021 14.7 0.5 0.021 14.7 0.5 1.7 2 0 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family Kinase-like PF14531.6 KEG09349.1 - 0.022 14.1 0.1 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 Kinase-like GDP_Man_Dehyd PF16363.5 KEG09350.1 - 3.3e-41 141.8 0.0 1.3e-40 139.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEG09350.1 - 1.2e-38 132.9 0.0 1.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEG09350.1 - 6.1e-07 28.7 0.0 8.2e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEG09350.1 - 6.2e-06 25.6 0.0 0.0014 17.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KEG09350.1 - 3.6e-05 23.3 0.0 6.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KEG09350.1 - 0.047 12.8 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF43 PF01861.16 KEG09350.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain PfkB PF00294.24 KEG09351.1 - 2.6e-58 197.7 0.2 3.4e-58 197.3 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase 2OG-FeII_Oxy_2 PF13532.6 KEG09352.1 - 5.5e-11 43.0 0.0 7.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KEG09352.1 - 0.0053 17.2 0.0 0.041 14.4 0.0 2.3 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily ERM PF00769.19 KEG09354.1 - 0.0045 16.8 19.2 0.0045 16.8 19.2 3.5 1 1 1 2 2 2 1 Ezrin/radixin/moesin family HALZ PF02183.18 KEG09354.1 - 0.015 15.5 23.8 0.22 11.8 1.1 6.8 7 0 0 7 7 6 0 Homeobox associated leucine zipper TLE_N PF03920.15 KEG09354.1 - 0.025 14.7 10.6 2.8 8.0 0.1 4.3 3 1 1 4 4 4 0 Groucho/TLE N-terminal Q-rich domain UPF0242 PF06785.11 KEG09354.1 - 0.047 13.8 40.9 0.089 12.9 11.0 4.6 3 2 2 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KEG09354.1 - 0.16 11.8 42.3 0.019 14.8 8.4 3.8 4 1 0 4 4 4 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 KEG09354.1 - 0.26 11.2 21.8 0.85 9.5 2.0 5.0 4 1 1 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor IFP_35_N PF07334.13 KEG09354.1 - 0.37 10.9 7.4 0.39 10.8 0.0 3.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlaC_arch PF05377.11 KEG09354.1 - 0.37 11.2 17.0 2.5 8.6 0.3 5.2 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 KEG09354.1 - 0.41 10.7 19.7 2.3 8.4 0.5 5.2 5 1 0 5 5 5 0 Protein of unknown function (DUF2730) Filament PF00038.21 KEG09354.1 - 0.53 9.8 43.5 0.086 12.4 13.8 4.2 3 1 1 4 4 4 0 Intermediate filament protein Lectin_N PF03954.14 KEG09354.1 - 1.2 8.9 16.6 0.83 9.4 0.3 4.0 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 KEG09354.1 - 1.6 9.3 11.1 33 5.1 0.0 4.4 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 KEG09354.1 - 2 8.9 8.5 4.6 7.7 0.1 4.3 4 2 0 4 4 4 0 Lipoprotein leucine-zipper DASH_Dad2 PF08654.10 KEG09354.1 - 2.5 8.6 10.2 2.2 8.7 0.1 3.3 3 1 0 3 3 2 0 DASH complex subunit Dad2 Spc7 PF08317.11 KEG09354.1 - 2.9 6.7 43.4 0.45 9.3 10.9 4.0 4 0 0 4 4 4 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KEG09354.1 - 4.2 7.8 22.3 3.6 7.9 0.6 6.0 5 2 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KEG09354.1 - 5.7 7.0 14.5 9.4 6.3 1.4 4.4 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIVA PF05103.13 KEG09354.1 - 5.9 7.0 31.9 0.14 12.2 7.7 4.1 3 2 1 4 4 4 0 DivIVA protein DUF4200 PF13863.6 KEG09354.1 - 7.5 7.0 45.5 0.04 14.3 12.1 4.7 4 1 1 5 5 4 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 KEG09354.1 - 7.9 6.7 28.4 0.86 9.7 1.0 5.6 4 2 1 5 5 5 0 bZIP transcription factor Ala_racemase_N PF01168.20 KEG09355.1 - 1.6e-39 135.8 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 KEG09355.1 - 1.5e-17 63.6 0.3 2.8e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain tRNA-synt_2d PF01409.20 KEG09355.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) UQ_con PF00179.26 KEG09356.1 - 4e-54 182.1 0.0 4.4e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEG09356.1 - 0.0036 17.6 0.0 0.0046 17.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KEG09356.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Torus PF16131.5 KEG09359.1 - 0.024 15.3 0.0 0.039 14.6 0.0 1.4 1 0 0 1 1 1 0 Torus domain Mito_carr PF00153.27 KEG09362.1 - 1.1e-31 108.5 7.6 6.7e-18 64.4 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein AA_permease_2 PF13520.6 KEG09363.1 - 2.4e-38 132.1 46.5 3.4e-38 131.6 46.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEG09363.1 - 1.5e-13 50.2 38.5 2.3e-13 49.6 38.5 1.3 1 0 0 1 1 1 1 Amino acid permease DUF4808 PF16066.5 KEG09365.1 - 0.047 14.3 0.0 0.057 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Glyco_hydro_3 PF00933.21 KEG09366.1 - 1.7e-55 188.7 0.0 1.3e-54 185.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEG09366.1 - 2.3e-54 184.5 0.0 5e-54 183.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KEG09366.1 - 3.3e-23 81.6 0.1 7e-23 80.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain GHL6 PF14871.6 KEG09366.1 - 0.1 12.8 0.1 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Sugar_tr PF00083.24 KEG09368.1 - 2.2e-89 300.4 27.7 3.8e-88 296.3 27.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEG09368.1 - 5.4e-12 45.3 34.0 8.5e-09 34.8 32.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily EIIC-GAT PF03611.14 KEG09368.1 - 0.00024 20.3 10.5 0.00024 20.3 10.5 3.3 1 1 2 3 3 3 1 PTS system sugar-specific permease component Paramecium_SA PF01508.16 KEG09368.1 - 2.9 8.4 12.4 0.45 11.0 5.1 2.4 1 1 1 2 2 2 0 Paramecium surface antigen domain PSI PF01437.25 KEG09368.1 - 5 7.7 10.8 23 5.6 10.9 2.0 1 1 1 2 2 2 0 Plexin repeat DUF1010 PF06231.11 KEG09370.1 - 0.12 12.9 1.2 26 5.4 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Steroid_dh PF02544.16 KEG09371.1 - 4.9e-05 23.4 0.8 0.0012 18.8 0.3 2.6 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase cNMP_binding PF00027.29 KEG09374.1 - 5.5e-15 55.2 0.1 2.1e-08 34.1 0.0 3.3 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain PCI PF01399.27 KEG09375.1 - 6.9e-20 71.5 0.1 1.3e-19 70.7 0.1 1.5 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 KEG09375.1 - 9.7e-16 58.0 2.3 2.2e-15 56.8 2.3 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal tRNA-synt_His PF13393.6 KEG09376.1 - 8.1e-38 130.4 0.0 1.7e-37 129.4 0.0 1.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KEG09376.1 - 9.8e-06 25.6 0.2 3.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEG09376.1 - 8.3e-05 22.6 0.0 0.00015 21.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RRS1 PF04939.12 KEG09377.1 - 2.7e-42 144.4 6.0 3.7e-42 143.9 6.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) MRP-S26 PF14943.6 KEG09377.1 - 4.7 7.1 14.7 1.6 8.6 5.9 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Cyt-b5 PF00173.28 KEG09378.1 - 3.9e-12 46.2 0.0 9e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 KEG09378.1 - 1.9e-10 41.0 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEG09378.1 - 1e-06 29.3 0.0 4.5e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KEG09378.1 - 0.026 14.6 0.1 0.08 13.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Pkinase PF00069.25 KEG09379.1 - 6.7e-69 232.2 0.0 8.6e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09379.1 - 2.5e-42 145.0 0.0 3.4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG09379.1 - 5.6e-07 29.2 0.1 8.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KEG09379.1 - 7.7e-05 21.6 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEG09379.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KEG09379.1 - 0.016 15.1 0.2 0.057 13.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family BBS2_C PF14782.6 KEG09380.1 - 2.6e-46 158.3 0.0 4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_N PF14781.6 KEG09380.1 - 5.9e-27 93.6 0.0 1.2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.6 KEG09380.1 - 1.5e-25 89.3 0.0 5.6e-25 87.5 0.0 2.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 KEG09380.1 - 0.036 14.2 0.5 0.16 12.1 0.5 2.1 1 0 0 1 1 1 0 FG-GAP repeat VCBS PF13517.6 KEG09380.1 - 0.041 14.5 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CHAP PF05257.16 KEG09381.1 - 3.6e-06 27.5 0.0 6.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 KEG09382.1 - 2.6e-05 24.7 0.1 6.9e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 CHAP domain zinc_ribbon_16 PF17034.5 KEG09383.1 - 0.011 16.0 11.2 0.056 13.7 11.2 2.1 1 1 0 1 1 1 0 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KEG09383.1 - 0.14 11.8 18.8 0.055 13.1 14.1 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Thioredoxin PF00085.20 KEG09384.1 - 0.0012 18.8 0.1 0.0028 17.6 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin DUF4542 PF15075.6 KEG09385.1 - 0.073 13.5 2.0 0.6 10.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) DnaJ PF00226.31 KEG09386.1 - 3.8e-10 39.7 0.2 6.7e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 KEG09386.1 - 1.8e-07 30.8 0.1 9.5e-07 28.5 0.0 1.9 1 1 1 2 2 2 1 X-domain of DnaJ-containing Ribosomal_S21 PF01165.20 KEG09386.1 - 0.059 13.1 0.1 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S21 T4SS-DNA_transf PF02534.14 KEG09386.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Peptidase_C2 PF00648.21 KEG09388.1 - 1.5e-60 204.8 0.4 2.2e-60 204.2 0.4 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG09388.1 - 1.1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) AAA_14 PF13173.6 KEG09389.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C2 PF00648.21 KEG09390.1 - 2.8e-69 233.4 0.0 3.9e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG09390.1 - 2.9e-14 53.3 0.0 6.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 KEG09391.1 - 4.8e-22 78.3 1.5 8.9e-22 77.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 KEG09392.1 - 1e-27 97.0 0.0 1.2e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease C2 PF00168.30 KEG09394.1 - 0.0029 17.9 0.0 1.7 9.0 0.0 4.1 3 1 0 3 3 3 1 C2 domain EBP50_C PF09007.11 KEG09394.1 - 6 7.9 12.0 1.3 10.0 2.1 3.4 3 0 0 3 3 3 0 EBP50, C-terminal PTEN_C2 PF10409.9 KEG09395.1 - 1.4e-11 44.2 0.0 7e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 KEG09395.1 - 6.5e-09 35.7 0.1 1.7e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG09395.1 - 8.5e-06 25.5 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEG09395.1 - 0.0024 18.0 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KEG09395.1 - 0.0028 17.7 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex24p PF06398.11 KEG09395.1 - 3.6 6.5 4.8 0.81 8.6 1.0 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin 2-Hacid_dh_C PF02826.19 KEG09396.1 - 5.3e-47 159.5 0.0 7.5e-47 159.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KEG09396.1 - 0.0027 17.3 0.0 0.0074 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KEG09396.1 - 0.0035 17.5 0.2 0.008 16.3 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KEG09396.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 KEG09396.1 - 0.02 15.5 0.1 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KEG09396.1 - 0.027 14.7 0.2 0.24 11.6 0.2 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Oxidored_nitro PF00148.19 KEG09396.1 - 0.064 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.19 KEG09397.1 - 4.2e-47 159.8 0.0 6e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KEG09397.1 - 0.0021 17.6 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KEG09397.1 - 0.0025 18.0 0.1 0.0036 17.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KEG09397.1 - 0.0079 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KEG09397.1 - 0.011 16.3 0.0 0.029 15.0 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KEG09397.1 - 0.017 15.4 0.2 0.12 12.6 0.2 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Oxidored_nitro PF00148.19 KEG09397.1 - 0.061 12.0 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ApbA PF02558.16 KEG09397.1 - 0.17 11.5 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cation_ATPase_C PF00689.21 KEG09398.1 - 0.0078 15.9 1.8 0.0078 15.9 1.8 3.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus FAM176 PF14851.6 KEG09398.1 - 0.058 13.1 0.2 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 FAM176 family CcmH PF03918.14 KEG09398.1 - 0.12 11.6 0.4 1.1 8.6 0.0 2.7 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Adeno_terminal PF02459.15 KEG09398.1 - 0.15 10.4 0.3 0.29 9.5 0.3 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein EphA2_TM PF14575.6 KEG09398.1 - 0.62 11.0 4.2 31 5.5 0.0 4.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain CPSF100_C PF13299.6 KEG09399.1 - 0.19 11.9 2.2 0.62 10.2 2.2 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 KEG09399.1 - 0.5 9.9 14.1 1.2 8.7 14.1 1.5 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 KEG09399.1 - 1 7.6 9.1 1.7 6.9 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 KEG09399.1 - 1.1 8.2 12.9 2.1 7.3 12.9 1.3 1 0 0 1 1 1 0 Paf1 PEX11 PF05648.14 KEG09400.1 - 0.0095 15.4 0.6 0.063 12.7 0.0 2.1 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2255 PF10012.9 KEG09400.1 - 0.049 13.8 0.2 0.09 12.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) DNA_methylase PF00145.17 KEG09401.1 - 4.7e-08 32.8 0.2 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Prok-E2_A PF14457.6 KEG09401.1 - 0.037 13.6 0.1 0.055 13.1 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A Ribosomal_S25 PF03297.15 KEG09402.1 - 8.3e-36 122.2 5.7 9.7e-36 122.0 5.7 1.1 1 0 0 1 1 1 1 S25 ribosomal protein ATP-synt_ab PF00006.25 KEG09403.1 - 9.3e-64 215.0 0.1 2.2e-63 213.8 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEG09403.1 - 1.3e-12 48.1 0.3 3.5e-12 46.7 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KEG09403.1 - 0.0095 16.4 0.1 0.056 13.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEG09403.1 - 0.012 16.0 1.6 0.25 11.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KEG09403.1 - 0.019 14.6 0.1 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEG09403.1 - 0.041 13.1 0.2 0.091 11.9 0.2 1.5 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 KEG09403.1 - 0.083 12.8 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 KEG09403.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 KEG09403.1 - 0.13 12.2 0.2 0.45 10.4 0.2 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 KEG09403.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea LMBR1 PF04791.16 KEG09404.1 - 1.7e-35 122.9 23.4 6.4e-25 88.0 5.4 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Peptidase_M3_N PF08439.10 KEG09404.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Oligopeptidase F eIF-1a PF01176.19 KEG09404.1 - 0.046 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Lig_chan PF00060.26 KEG09404.1 - 0.83 9.5 3.6 0.75 9.6 0.1 2.7 2 0 0 2 2 2 0 Ligand-gated ion channel DUF3810 PF12725.7 KEG09404.1 - 1.4 8.2 12.0 0.55 9.5 0.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3810) Acetyltransf_16 PF05301.11 KEG09405.1 - 6.2e-49 166.1 0.0 8.3e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 KEG09405.1 - 0.00067 20.0 0.0 0.0031 17.9 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEG09405.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.22 KEG09407.1 - 6.1e-179 595.4 0.0 6.9e-179 595.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BNR_3 PF13859.6 KEG09408.1 - 5.4e-80 269.0 0.0 8.2e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.6 KEG09408.1 - 3.1e-17 62.8 0.0 1.1e-15 57.7 0.1 2.3 1 1 0 1 1 1 1 BNR repeat-like domain Laminin_G_3 PF13385.6 KEG09408.1 - 3.8e-07 30.4 0.1 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily BNR PF02012.20 KEG09408.1 - 0.00044 19.8 13.7 0.82 9.9 0.1 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat CyRPA PF18638.1 KEG09408.1 - 0.097 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain Sortilin-Vps10 PF15902.5 KEG09408.1 - 0.23 10.2 0.9 25 3.5 0.1 2.8 2 1 1 3 3 3 0 Sortilin, neurotensin receptor 3, Methyltransf_5 PF01795.19 KEG09409.1 - 2.1e-29 103.0 0.0 3e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KEG09409.1 - 0.00012 22.7 0.0 0.00064 20.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG09409.1 - 0.00024 21.0 0.0 0.016 15.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KEG09409.1 - 0.0022 19.0 0.0 0.014 16.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain TMEM234 PF10639.9 KEG09410.1 - 3.9e-35 120.4 1.7 4.6e-35 120.1 1.7 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KEG09410.1 - 5.1e-10 39.7 7.8 2.5e-06 27.7 2.5 2.0 1 1 1 2 2 2 2 EamA-like transporter family DUF2955 PF11168.8 KEG09410.1 - 0.5 10.2 6.9 0.23 11.3 5.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) DUF4229 PF14012.6 KEG09410.1 - 1.5 9.0 8.6 9.8 6.4 5.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) Ribosomal_S9 PF00380.19 KEG09411.1 - 1.3e-06 28.9 0.0 2.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 WD40_4 PF16300.5 KEG09412.1 - 1.4e-11 44.1 0.0 2.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 KEG09412.1 - 9.5e-09 35.0 0.0 2.5e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KEG09412.1 - 9.2e-08 32.6 9.1 0.079 13.9 0.1 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG09412.1 - 8.4e-07 29.2 0.2 0.0002 21.6 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cu-oxidase_2 PF07731.14 KEG09412.1 - 0.038 13.7 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Multicopper oxidase AMOP PF03782.17 KEG09412.1 - 0.073 13.2 0.6 0.68 10.0 0.0 2.5 2 1 1 3 3 3 0 AMOP domain UPF0242 PF06785.11 KEG09412.1 - 0.078 13.1 1.2 0.13 12.4 1.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CTD PF12815.7 KEG09412.1 - 0.14 12.7 4.7 0.34 11.5 4.7 1.6 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 eIF3_subunit PF08597.10 KEG09414.1 - 1.7 8.5 11.0 1.9 8.4 11.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cyclin_N PF00134.23 KEG09415.1 - 1.9e-26 92.3 2.2 5.6e-25 87.5 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain MATH PF00917.26 KEG09418.1 - 7.4e-05 22.9 0.1 0.00019 21.6 0.1 1.7 1 0 0 1 1 1 1 MATH domain Exonuc_VII_L PF02601.15 KEG09418.1 - 5.6 6.4 16.5 14 5.1 16.5 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 KEG09418.1 - 7.1 7.3 20.0 41 4.9 0.5 3.5 2 1 0 2 2 2 0 Initiation control protein YabA UPF0220 PF05255.11 KEG09419.1 - 5.9e-14 51.9 1.2 8.6e-14 51.4 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) TMEM171 PF15471.6 KEG09419.1 - 0.052 12.5 0.3 0.064 12.2 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3267 PF11667.8 KEG09419.1 - 0.066 13.5 1.3 0.12 12.7 1.2 1.5 1 1 0 1 1 1 0 Putative zincin peptidase DUF2721 PF11026.8 KEG09419.1 - 0.57 10.1 4.9 3.2 7.6 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) CPSase_L_D3 PF02787.19 KEG09420.1 - 0.088 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Pro_isomerase PF00160.21 KEG09421.1 - 8e-20 71.7 0.0 1e-19 71.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CmcI PF04989.12 KEG09422.1 - 1.8e-38 132.3 0.1 6.4e-38 130.5 0.1 1.7 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 KEG09422.1 - 0.0018 19.3 0.0 0.0037 18.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG09422.1 - 0.11 12.3 0.0 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain LIM PF00412.22 KEG09424.1 - 0.00011 22.4 13.7 0.0024 18.0 12.5 2.6 2 1 1 3 3 3 2 LIM domain ACC_epsilon PF13822.6 KEG09424.1 - 4.5 8.0 9.0 12 6.6 9.0 1.8 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Auto_anti-p27 PF06677.12 KEG09424.1 - 4.9 7.4 6.9 0.79 9.9 2.2 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Peptidase_C54 PF03416.19 KEG09425.1 - 1.2e-43 149.6 0.0 5e-43 147.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C54 zf-C2H2_4 PF13894.6 KEG09426.1 - 5.8e-18 64.0 53.0 0.0015 19.2 0.1 8.7 9 0 0 9 9 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEG09426.1 - 1.1e-13 51.0 19.9 0.00065 19.9 0.1 6.0 6 0 0 6 6 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KEG09426.1 - 3.9e-13 49.0 47.2 0.0096 16.3 0.1 8.8 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-Di19 PF05605.12 KEG09426.1 - 3.6e-11 43.2 40.3 5.2e-05 23.5 4.8 7.2 7 0 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KEG09426.1 - 9.6e-09 35.3 26.3 0.0026 18.1 0.0 6.9 7 1 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KEG09426.1 - 6.8e-07 29.1 46.1 8.8e-05 22.4 0.3 7.3 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEG09426.1 - 0.00013 22.3 29.3 1.5 9.2 0.1 7.0 3 2 3 6 6 6 3 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KEG09426.1 - 0.0041 17.7 28.6 11 6.7 0.2 7.2 4 1 3 7 7 7 0 FOXP coiled-coil domain zf-met2 PF12907.7 KEG09426.1 - 0.0094 16.1 21.2 0.27 11.4 0.7 6.1 5 1 1 6 6 6 1 Zinc-binding zf-H2C2_2 PF13465.6 KEG09426.1 - 0.015 15.7 0.4 0.015 15.7 0.4 7.7 8 2 0 8 8 7 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 KEG09426.1 - 0.026 14.3 28.9 0.084 12.6 0.1 5.7 6 0 0 6 6 6 0 zinc-finger C2H2-type zf_ZIC PF18366.1 KEG09426.1 - 0.032 14.3 26.1 0.21 11.7 0.2 6.9 7 0 0 7 7 7 0 Zic proteins zinc finger domain zf_Hakai PF18408.1 KEG09426.1 - 0.1 12.4 0.0 0.1 12.4 0.0 5.5 8 0 0 8 8 7 0 C2H2 Hakai zinc finger domain zf-C2HC_2 PF13913.6 KEG09426.1 - 0.19 11.7 0.0 0.19 11.7 0.0 5.0 6 0 0 6 6 4 0 zinc-finger of a C2HC-type zf_C2H2_ZHX PF18387.1 KEG09426.1 - 0.35 10.6 0.1 0.35 10.6 0.1 4.6 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 KEG09426.1 - 0.68 8.4 21.9 1.5 7.2 0.1 5.2 4 1 2 6 6 6 0 Protein of unknown function (DUF629) OrsD PF12013.8 KEG09426.1 - 0.99 9.9 28.8 0.13 12.7 2.3 5.7 2 1 4 6 6 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 KEG09426.1 - 2.6 7.2 22.9 5.3 6.1 5.8 5.6 3 1 1 5 5 5 0 Putative actin-like family zf_UBZ PF18439.1 KEG09426.1 - 5.3 6.7 22.3 11 5.7 0.3 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger RNase_T PF00929.24 KEG09428.1 - 1.5e-17 64.6 0.0 3.3e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.6 KEG09428.1 - 2.6e-12 47.0 0.0 1.5e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KEG09428.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1679 PF07914.11 KEG09429.1 - 0.23 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MatE PF01554.18 KEG09431.1 - 3.4e-27 95.1 30.8 1.9e-14 53.6 8.7 2.6 3 0 0 3 3 3 2 MatE 3Beta_HSD PF01073.19 KEG09433.1 - 2.6e-38 131.6 0.0 3.4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEG09433.1 - 1.1e-24 87.2 0.0 1.5e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEG09433.1 - 9.7e-15 54.9 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEG09433.1 - 6.2e-13 48.8 0.0 2.1e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEG09433.1 - 8.2e-13 48.1 0.1 1.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KEG09433.1 - 9.5e-10 38.0 0.0 2e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEG09433.1 - 6.9e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KEG09433.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KEG09433.1 - 0.00045 20.2 0.2 0.0014 18.5 0.2 1.8 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 KEG09433.1 - 0.00082 18.9 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KEG09433.1 - 0.0061 16.8 0.1 0.035 14.4 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Peptidase_S9 PF00326.21 KEG09434.1 - 4.2e-34 117.9 0.0 8.5e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KEG09434.1 - 4.7e-23 81.7 0.0 7.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Glyco_hydro_31 PF01055.26 KEG09436.1 - 8.2e-96 321.9 0.0 9.6e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 IQ PF00612.27 KEG09439.1 - 2.2e-09 36.3 18.7 0.00044 19.8 0.5 4.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif His_Phos_1 PF00300.22 KEG09440.1 - 2e-17 63.5 1.6 1.4e-10 41.2 0.1 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_C58 PF03543.14 KEG09440.1 - 0.076 12.7 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen RCC1 PF00415.18 KEG09441.1 - 3.3e-26 91.7 16.3 1.2e-08 35.4 0.1 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG09441.1 - 2.2e-16 59.2 27.6 4.1e-06 26.4 1.2 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat TMF_DNA_bd PF12329.8 KEG09442.1 - 1.2e-05 25.2 22.0 0.5 10.4 0.4 5.8 3 2 2 5 5 5 3 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 KEG09442.1 - 0.00018 22.1 15.2 0.0005 20.6 6.6 2.7 3 0 0 3 3 3 2 Fez1 DUF4407 PF14362.6 KEG09442.1 - 0.0088 15.4 30.5 0.011 15.1 13.4 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4407) RNA_binding PF01877.17 KEG09442.1 - 0.012 15.9 0.6 0.032 14.5 0.1 2.0 2 0 0 2 2 2 0 RNA binding Spc7 PF08317.11 KEG09442.1 - 0.013 14.5 21.5 0.11 11.4 8.3 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KEG09442.1 - 0.023 14.5 4.1 0.67 9.9 1.3 4.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase APG6_N PF17675.1 KEG09442.1 - 0.11 13.0 35.0 0.87 10.1 16.2 4.0 3 1 0 3 3 3 0 Apg6 coiled-coil region Atg14 PF10186.9 KEG09442.1 - 0.14 11.2 10.3 0.11 11.6 6.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4094 PF13334.6 KEG09442.1 - 0.33 11.4 7.7 4.1 7.9 0.4 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) DUF3552 PF12072.8 KEG09442.1 - 0.38 10.1 22.9 0.44 9.9 12.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MCC-bdg_PDZ PF10506.9 KEG09442.1 - 0.74 9.9 8.5 0.2 11.7 1.4 3.4 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4618 PF15397.6 KEG09442.1 - 0.78 9.1 9.8 8.1 5.8 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FAM76 PF16046.5 KEG09442.1 - 1.6 8.0 14.0 6.1 6.1 0.2 3.3 2 1 2 4 4 4 0 FAM76 protein zf-C4H2 PF10146.9 KEG09442.1 - 2.7 8.2 8.8 0.37 11.1 1.9 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein FPP PF05911.11 KEG09442.1 - 3.1 5.9 16.8 0.054 11.7 3.8 2.9 3 0 0 3 3 3 0 Filament-like plant protein, long coiled-coil KLRAQ PF10205.9 KEG09442.1 - 3.3 8.0 12.6 4.3 7.6 4.8 2.9 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein ADIP PF11559.8 KEG09442.1 - 8.5 6.4 20.4 7.6 6.6 3.0 3.9 3 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 KEG09442.1 - 9 6.5 24.5 0.19 11.9 5.5 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding MCC-bdg_PDZ PF10506.9 KEG09443.1 - 6.7e-05 22.8 1.0 6.7e-05 22.8 1.0 2.1 2 1 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.9 KEG09443.1 - 0.012 14.7 10.2 0.02 14.0 10.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3140 PF11338.8 KEG09443.1 - 0.016 15.6 3.5 0.025 15.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) APG6_N PF17675.1 KEG09443.1 - 0.019 15.5 20.3 0.027 15.0 20.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TetR_C_15 PF17918.1 KEG09443.1 - 0.071 13.9 0.2 0.071 13.9 0.2 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BT1 PF03092.16 KEG09443.1 - 0.082 11.1 2.6 0.1 10.8 2.6 1.1 1 0 0 1 1 1 0 BT1 family Csm1_N PF18504.1 KEG09443.1 - 0.12 12.8 0.4 0.12 12.8 0.4 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 KEG09443.1 - 0.18 12.0 13.3 0.24 11.6 13.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KEG09443.1 - 0.26 11.6 2.5 0.52 10.6 2.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Herpes_UL6 PF01763.16 KEG09443.1 - 0.26 9.7 5.9 0.29 9.6 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Phage_GPO PF05929.11 KEG09443.1 - 0.87 9.2 11.6 1.3 8.6 11.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2347 PF09804.9 KEG09443.1 - 2 7.9 5.7 2.6 7.5 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) V_ATPase_I PF01496.19 KEG09443.1 - 2.1 6.2 8.5 2.5 5.9 8.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 KEG09443.1 - 2.5 8.2 22.2 6.7 6.8 22.0 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SLC12 PF03522.15 KEG09443.1 - 2.8 6.8 10.5 3.5 6.5 10.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Jnk-SapK_ap_N PF09744.9 KEG09443.1 - 3 8.1 17.8 4.4 7.5 17.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Metal_resist PF13801.6 KEG09443.1 - 4.5 7.5 18.1 0.78 9.9 9.3 2.2 1 1 1 2 2 2 0 Heavy-metal resistance PRKG1_interact PF15898.5 KEG09443.1 - 6 7.8 19.6 19 6.2 0.5 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Sec62 PF03839.16 KEG09443.1 - 9.3 5.7 7.6 11 5.4 7.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Herpes_BLRF2 PF05812.12 KEG09444.1 - 0.02 15.0 1.3 0.058 13.5 1.3 1.8 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DMPK_coil PF08826.10 KEG09444.1 - 0.8 9.9 7.4 3.8 7.7 0.0 4.2 4 0 0 4 4 4 0 DMPK coiled coil domain like Jnk-SapK_ap_N PF09744.9 KEG09444.1 - 1.5 9.0 6.6 2.7 8.2 2.3 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 BRE1 PF08647.11 KEG09444.1 - 1.7 8.8 7.8 1.4 9.1 2.4 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase UCH_C PF18031.1 KEG09444.1 - 2.7 7.9 7.6 1.3 9.0 1.3 2.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases TPR_19 PF14559.6 KEG09445.1 - 1.8e-11 44.4 1.2 5.7e-05 23.5 0.1 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG09445.1 - 6.4e-10 38.4 9.1 0.042 14.0 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG09445.1 - 2.5e-09 37.2 22.0 0.0018 18.9 0.1 9.1 3 3 5 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09445.1 - 1.5e-08 34.1 4.2 0.15 12.0 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG09445.1 - 9.4e-07 28.6 1.8 18 5.8 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG09445.1 - 4e-06 27.4 18.2 0.002 18.8 5.6 5.0 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG09445.1 - 7.3e-06 25.6 0.3 2.6 8.3 0.0 5.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09445.1 - 1.7e-05 25.0 20.9 0.67 10.3 2.0 6.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEG09445.1 - 3.3e-05 23.9 0.8 0.043 14.2 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG09445.1 - 0.00012 22.3 6.1 0.83 9.9 0.5 4.0 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KEG09445.1 - 0.00029 20.1 1.5 0.23 10.6 0.0 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KEG09445.1 - 0.00096 18.9 4.9 0.0029 17.4 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 KEG09445.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Coatomer epsilon subunit NARP1 PF12569.8 KEG09445.1 - 0.02 13.8 0.1 0.22 10.4 0.1 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KEG09445.1 - 1.1 10.1 6.2 44 5.0 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat La PF05383.17 KEG09446.1 - 4.4e-21 74.7 0.1 8.4e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KEG09446.1 - 6.8e-09 35.4 0.0 3.7e-08 33.1 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEG09446.1 - 1.4e-05 25.0 5.8 0.00085 19.3 0.2 3.0 2 1 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 KEG09446.1 - 0.0034 17.5 0.0 0.076 13.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif API5 PF05918.11 KEG09446.1 - 0.61 8.8 9.1 0.077 11.8 2.4 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Spt5_N PF11942.8 KEG09446.1 - 1.5 9.9 7.2 2.3 9.3 1.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Biotin_lipoyl PF00364.22 KEG09447.1 - 8.2e-20 70.4 0.2 5.9e-15 54.9 0.2 2.4 1 1 1 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 KEG09447.1 - 0.058 14.1 0.3 0.13 13.0 0.3 1.5 1 0 0 1 1 1 0 HlyD family secretion protein TSC22 PF01166.18 KEG09448.1 - 0.00096 19.4 2.5 0.0038 17.5 2.5 2.1 1 0 0 1 1 1 1 TSC-22/dip/bun family UPF0242 PF06785.11 KEG09448.1 - 0.0012 19.0 3.4 0.0012 19.0 3.4 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KEG09448.1 - 0.007 16.2 4.2 0.007 16.2 4.2 2.3 2 0 0 2 2 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KEG09448.1 - 0.0077 16.3 3.6 0.0077 16.3 3.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor SlyX PF04102.12 KEG09448.1 - 0.063 13.9 0.4 0.063 13.9 0.4 3.8 4 1 0 4 4 4 0 SlyX GIT_CC PF16559.5 KEG09448.1 - 0.11 12.3 1.4 0.31 10.9 0.3 2.3 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor WAC_Acf1_DNA_bd PF10537.9 KEG09448.1 - 0.13 12.8 2.9 0.33 11.5 2.9 1.6 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal CZB PF13682.6 KEG09448.1 - 0.18 12.3 1.4 0.52 10.8 1.4 1.8 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain CortBP2 PF09727.9 KEG09448.1 - 0.34 10.8 23.1 2.2 8.2 6.4 2.6 2 0 0 2 2 2 0 Cortactin-binding protein-2 zf-C4H2 PF10146.9 KEG09448.1 - 0.82 9.9 9.9 0.68 10.2 2.5 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein APG6_N PF17675.1 KEG09448.1 - 1.7 9.2 22.6 0.94 10.0 8.5 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Leu_zip PF15294.6 KEG09448.1 - 1.7 8.1 14.2 0.082 12.4 2.7 2.2 2 0 0 2 2 2 0 Leucine zipper DUF4164 PF13747.6 KEG09448.1 - 2.8 8.3 19.4 0.051 13.9 8.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) YabA PF06156.13 KEG09448.1 - 2.8 8.6 14.2 0.082 13.6 0.7 2.8 2 1 0 2 2 2 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 KEG09448.1 - 6.2 6.3 15.2 0.062 12.9 2.8 2.5 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 KEG09448.1 - 7 5.9 16.8 0.26 10.6 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ins134_P3_kin PF05770.11 KEG09449.1 - 1.9e-06 27.6 0.0 0.078 12.5 0.0 2.6 2 1 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain CENP-K PF11802.8 KEG09452.1 - 0.00025 20.7 2.8 0.00025 20.7 2.8 3.9 2 2 2 4 4 4 1 Centromere-associated protein K HAP1_N PF04849.13 KEG09452.1 - 0.0039 16.4 11.2 0.0039 16.4 11.2 4.5 3 2 2 5 5 5 2 HAP1 N-terminal conserved region Tup_N PF08581.10 KEG09452.1 - 0.014 15.7 1.6 0.014 15.7 1.6 5.6 5 1 0 5 5 5 0 Tup N-terminal FPP PF05911.11 KEG09452.1 - 0.036 12.3 33.9 0.065 11.4 8.0 2.3 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KEG09452.1 - 0.68 8.8 47.2 0.093 11.6 12.5 3.4 2 2 1 3 3 3 0 Spc7 kinetochore protein DUF3496 PF12001.8 KEG09452.1 - 5 7.6 10.7 0.56 10.6 5.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) Nup88 PF10168.9 KEG09453.1 - 0.046 11.5 6.0 0.71 7.6 4.8 2.2 2 0 0 2 2 2 0 Nuclear pore component DUF3552 PF12072.8 KEG09453.1 - 0.071 12.5 12.0 0.02 14.3 8.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) OmpH PF03938.14 KEG09453.1 - 0.085 13.2 7.9 0.2 12.0 7.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4618 PF15397.6 KEG09453.1 - 0.11 11.8 5.7 0.18 11.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Nup54 PF13874.6 KEG09453.1 - 1.1 9.4 11.3 2.6 8.1 11.3 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Fez1 PF06818.15 KEG09453.1 - 9 6.7 12.8 18 5.7 12.8 1.4 1 0 0 1 1 1 0 Fez1 Ank_2 PF12796.7 KEG09454.1 - 8.9e-06 26.2 0.0 0.014 16.0 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG09454.1 - 1.6e-05 25.3 0.0 0.00032 21.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG09454.1 - 0.00045 20.5 0.1 1.2 10.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KEG09454.1 - 0.14 12.6 0.0 0.74 10.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FAD_binding_7 PF03441.14 KEG09455.1 - 5.6e-33 114.1 0.3 1.1e-32 113.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KEG09455.1 - 2.1e-19 70.1 0.0 6.7e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 DNA photolyase zf-RING_2 PF13639.6 KEG09456.1 - 1.5e-10 41.2 4.4 1.8e-09 37.7 1.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KEG09456.1 - 2.2e-10 40.7 5.8 4.6e-10 39.6 3.7 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KEG09456.1 - 3e-07 30.2 3.9 2.4e-06 27.3 1.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG09456.1 - 1.1e-05 25.2 1.5 3.9e-05 23.4 1.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG09456.1 - 1.3e-05 25.2 0.9 3e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KEG09456.1 - 0.0002 21.0 1.0 0.037 13.8 0.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger zinc_ribbon_16 PF17034.5 KEG09456.1 - 0.00053 20.2 0.5 0.00091 19.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon like family Prok-RING_4 PF14447.6 KEG09456.1 - 0.00084 19.1 0.4 0.00084 19.1 0.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEG09456.1 - 0.00087 19.1 3.1 0.0023 17.7 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG09456.1 - 0.00096 19.1 1.8 0.0025 17.8 1.3 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEG09456.1 - 0.0014 18.5 1.1 0.0033 17.3 0.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 KEG09456.1 - 0.035 13.9 2.7 0.038 13.8 0.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KEG09456.1 - 0.058 13.0 1.0 0.058 13.0 1.0 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KEG09456.1 - 0.09 12.8 0.6 0.21 11.7 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 KEG09456.1 - 0.094 13.0 0.9 0.19 12.0 0.9 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KEG09456.1 - 0.16 12.2 4.4 0.75 10.0 4.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KEG09456.1 - 0.18 12.0 2.1 0.39 10.9 0.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KEG09456.1 - 0.49 10.6 4.6 0.68 10.1 2.0 2.3 2 0 0 2 2 2 0 RING-variant domain UPF0547 PF10571.9 KEG09456.1 - 9.1 6.5 9.2 0.75 9.9 0.4 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 K_channel_TID PF07941.11 KEG09457.1 - 0.24 11.9 6.2 0.099 13.1 3.8 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CHASE PF03924.13 KEG09458.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 CHASE domain Pkinase PF00069.25 KEG09459.1 - 5.7e-33 114.4 0.1 8.7e-15 54.8 0.0 4.1 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09459.1 - 1.5e-10 40.8 0.1 7.5e-06 25.4 0.1 4.0 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG09459.1 - 0.017 14.5 0.2 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KEG09460.1 - 2.8e-08 33.5 0.1 0.0044 16.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Limkain-b1 PF11608.8 KEG09461.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Pet191_N PF10203.9 KEG09462.1 - 0.0049 17.1 4.4 0.17 12.2 0.7 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 KEG09462.1 - 0.42 10.7 8.2 0.39 10.8 0.6 2.7 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KEG09462.1 - 1.7 8.9 8.9 0.2 11.8 2.7 2.5 3 0 0 3 3 3 0 CHCH domain FtsJ PF01728.19 KEG09463.1 - 0.00031 20.9 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Peptidase_S28 PF05577.12 KEG09464.1 - 7.9e-56 189.7 4.4 1.9e-55 188.5 4.4 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KEG09464.1 - 8.6e-08 31.3 0.5 1.7e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 KEG09464.1 - 0.0001 22.0 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEG09464.1 - 0.00014 21.4 0.1 0.00024 20.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 KEG09464.1 - 0.19 10.9 0.1 0.28 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) OmpH PF03938.14 KEG09465.1 - 0.0035 17.7 1.6 0.0042 17.4 1.6 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) S6OS1 PF15676.5 KEG09465.1 - 0.0041 15.7 2.2 0.0045 15.5 2.2 1.0 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family BLOC1_2 PF10046.9 KEG09465.1 - 0.005 17.1 2.0 0.0062 16.8 2.0 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 KASH_CCD PF14662.6 KEG09465.1 - 0.0051 16.7 4.5 0.0063 16.4 4.5 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH BRF1 PF07741.13 KEG09465.1 - 0.0079 16.5 0.3 0.0087 16.4 0.3 1.2 1 0 0 1 1 1 1 Brf1-like TBP-binding domain F-112 PF09645.10 KEG09465.1 - 0.01 15.9 0.3 0.011 15.8 0.3 1.2 1 0 0 1 1 1 0 F-112 protein Taxilin PF09728.9 KEG09465.1 - 0.014 14.6 8.2 0.064 12.4 8.2 1.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein RmuC PF02646.16 KEG09465.1 - 0.018 14.2 3.1 0.022 13.9 3.1 1.0 1 0 0 1 1 1 0 RmuC family FUSC PF04632.12 KEG09465.1 - 0.06 11.9 1.0 0.06 11.9 1.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family USP7_ICP0_bdg PF12436.8 KEG09465.1 - 0.081 12.2 2.5 0.091 12.1 2.5 1.1 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 HDAC4_Gln PF12203.8 KEG09465.1 - 0.12 12.6 12.4 0.15 12.3 12.4 1.1 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 SKA2 PF16740.5 KEG09465.1 - 0.15 11.9 6.1 0.26 11.1 6.2 1.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Phage_sheath_1 PF04984.14 KEG09465.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Mst1_SARAH PF11629.8 KEG09465.1 - 0.36 10.9 6.1 6.8 6.9 0.1 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 GIT_CC PF16559.5 KEG09465.1 - 0.82 9.6 4.7 1.8 8.5 4.7 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CDI PF02234.19 KEG09465.1 - 3 8.1 9.1 0.6 10.3 0.9 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor PAP_assoc PF03828.19 KEG09466.1 - 1.6e-11 44.2 0.0 3.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-RING_2 PF13639.6 KEG09466.1 - 0.067 13.5 4.5 0.19 12.1 4.5 1.8 1 0 0 1 1 1 0 Ring finger domain SPRY PF00622.28 KEG09467.1 - 0.047 13.8 0.0 0.094 12.8 0.0 1.5 1 1 0 1 1 1 0 SPRY domain Brucella_OMP2 PF05244.11 KEG09467.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Brucella outer membrane protein 2 Neuralized PF07177.12 KEG09467.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Neuralized Ribosomal_S24e PF01282.19 KEG09468.1 - 1.3e-28 98.8 0.0 2.8e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S24e ASH PF15780.5 KEG09469.1 - 3.7e-08 33.5 0.1 0.12 12.6 0.0 6.2 5 1 1 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KEG09469.1 - 0.00082 19.2 0.0 0.1 12.4 0.0 4.0 5 0 0 5 5 5 1 MSP (Major sperm protein) domain KASH PF10541.9 KEG09470.1 - 0.35 11.2 4.2 0.8 10.0 4.2 1.5 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF2647 PF10839.8 KEG09471.1 - 0.019 15.0 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) ThiC_Rad_SAM PF01964.18 KEG09471.1 - 0.21 10.3 2.3 0.33 9.7 2.3 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family GATA PF00320.27 KEG09471.1 - 0.83 9.3 9.5 0.22 11.2 0.8 3.0 2 0 0 2 2 2 0 GATA zinc finger Toxin_8 PF07365.12 KEG09472.1 - 0.087 13.0 0.1 0.47 10.7 0.1 2.4 1 0 0 1 1 1 0 Alpha conotoxin precursor SF3A2 PF16835.5 KEG09473.1 - 1.3e-18 67.1 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KEG09474.1 - 2.5e-06 27.7 1.5 4.6e-06 26.8 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEG09474.1 - 0.019 15.2 1.2 0.035 14.4 1.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2058 PF09831.9 KEG09474.1 - 0.64 10.2 6.7 0.9 9.7 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AMP-binding PF00501.28 KEG09475.1 - 2.1e-22 79.3 0.8 1.3e-09 37.2 0.0 4.0 3 1 0 3 3 3 3 AMP-binding enzyme Inhibitor_I42 PF09394.10 KEG09477.1 - 3.4e-15 56.2 0.0 4.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 DUF5599 PF18141.1 KEG09477.1 - 0.029 14.6 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) CGI-121 PF08617.10 KEG09478.1 - 2.3e-19 70.1 0.1 2.7e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 4PPT_N PF17837.1 KEG09478.1 - 0.036 14.2 0.2 0.078 13.1 0.2 1.7 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain SET PF00856.28 KEG09479.1 - 2.1e-08 34.7 0.0 2.2e-07 31.4 0.0 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KEG09479.1 - 0.02 15.5 0.0 0.92 10.2 0.0 2.3 2 0 0 2 2 2 0 SAF domain GFA PF04828.14 KEG09479.1 - 0.83 10.0 0.0 0.83 10.0 0.0 3.4 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme GCV_T PF01571.21 KEG09480.1 - 3.5e-08 33.1 0.0 5.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Serglycin PF04360.12 KEG09480.1 - 0.0072 16.3 0.5 0.011 15.7 0.5 1.3 1 0 0 1 1 1 1 Serglycin Porin_3 PF01459.22 KEG09481.1 - 0.0086 15.6 0.6 0.1 12.0 0.6 2.2 1 1 0 1 1 1 1 Eukaryotic porin Mucin-like PF16058.5 KEG09482.1 - 0.092 12.8 0.4 0.092 12.8 0.4 1.9 2 0 0 2 2 2 0 Mucin-like SUIM_assoc PF16619.5 KEG09483.1 - 0.028 14.5 2.0 2.9 8.0 0.4 3.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SUIM_assoc PF16619.5 KEG09484.1 - 0.0029 17.6 4.1 6.5 6.9 0.0 3.3 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 eIF2_C PF09173.11 KEG09485.1 - 1.2e-26 92.8 0.2 2.1e-26 92.0 0.2 1.4 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KEG09485.1 - 1.5e-09 37.6 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEG09485.1 - 5.4e-06 26.7 2.3 4.4e-05 23.8 0.4 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KEG09485.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KEG09485.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_pol_Rbc25 PF08292.12 KEG09486.1 - 9.4e-29 100.3 0.0 2e-28 99.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KEG09486.1 - 2.5e-25 88.6 0.0 3.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KEG09486.1 - 0.06 13.7 0.5 1.3 9.4 0.5 2.2 1 1 0 1 1 1 0 S1 RNA binding domain Motile_Sperm PF00635.26 KEG09487.1 - 1.3e-14 54.0 1.5 2.5e-14 53.0 1.5 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2116 PF09889.9 KEG09487.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SNARE PF05739.19 KEG09487.1 - 0.025 14.6 0.6 0.053 13.5 0.6 1.6 1 0 0 1 1 1 0 SNARE domain Glycophorin_A PF01102.18 KEG09487.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A LCAT PF02450.15 KEG09488.1 - 1.7e-52 178.9 0.0 6.9e-38 130.8 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase IFT57 PF10498.9 KEG09489.1 - 9.6e-05 21.5 3.6 0.00014 21.0 3.6 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 bZIP_1 PF00170.21 KEG09489.1 - 0.0044 17.1 0.7 0.0044 17.1 0.7 2.0 2 0 0 2 2 2 1 bZIP transcription factor OmpH PF03938.14 KEG09489.1 - 0.011 16.1 8.1 0.019 15.3 8.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KEG09489.1 - 0.024 15.2 6.5 0.024 15.2 6.5 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 KEG09489.1 - 0.033 14.3 4.7 0.061 13.4 4.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KEG09489.1 - 0.057 12.8 11.0 0.097 12.0 11.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 KEG09489.1 - 0.061 11.3 0.5 0.077 11.0 0.5 1.1 1 0 0 1 1 1 0 Prominin DUF641 PF04859.12 KEG09489.1 - 0.074 13.4 5.3 0.071 13.4 3.9 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FapA PF03961.13 KEG09489.1 - 0.099 11.2 1.0 0.14 10.8 1.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 KEG09489.1 - 0.14 12.5 6.5 0.34 11.3 6.5 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 KEG09489.1 - 0.18 12.2 6.0 0.16 12.4 2.8 2.5 2 1 1 3 3 2 0 Cell division protein ZapB Fmp27_WPPW PF10359.9 KEG09489.1 - 0.23 10.3 3.3 0.33 9.8 3.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain KLRAQ PF10205.9 KEG09489.1 - 0.27 11.5 7.0 0.79 10.0 6.3 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein RasGAP_C PF03836.15 KEG09489.1 - 0.29 11.3 6.3 0.34 11.1 5.3 1.6 2 0 0 2 2 2 0 RasGAP C-terminus THOC7 PF05615.13 KEG09489.1 - 0.36 11.1 9.6 0.14 12.4 6.9 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 V_ATPase_I PF01496.19 KEG09489.1 - 0.54 8.1 2.0 0.7 7.7 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.19 KEG09489.1 - 1.7 8.3 7.3 0.32 10.7 3.0 1.9 2 1 1 3 3 3 0 GrpE TMF_TATA_bd PF12325.8 KEG09489.1 - 2.7 8.2 9.4 0.12 12.5 1.6 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KEG09489.1 - 2.9 8.0 9.6 2.4 8.3 5.8 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 KEG09489.1 - 5.8 6.8 11.7 0.11 12.3 3.9 2.0 2 1 1 3 3 2 0 Septum formation initiator HALZ PF02183.18 KEG09489.1 - 8.4 6.7 10.5 0.061 13.5 1.6 2.1 3 0 0 3 3 1 0 Homeobox associated leucine zipper CDC50 PF03381.15 KEG09490.1 - 1.2e-59 202.2 0.0 1.7e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RRF_GI PF12614.8 KEG09493.1 - 0.046 13.9 0.6 0.14 12.3 0.6 1.7 1 0 0 1 1 1 0 Ribosome recycling factor DUF732 PF05305.14 KEG09493.1 - 0.071 13.5 0.1 0.3 11.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) zf-B_box PF00643.24 KEG09494.1 - 4.2e-09 36.4 1.2 8.4e-09 35.4 1.2 1.5 1 0 0 1 1 1 1 B-box zinc finger AAA_13 PF13166.6 KEG09494.1 - 0.08 11.6 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 KEG09494.1 - 0.12 12.3 5.5 1 9.3 4.3 2.2 1 1 1 2 2 2 0 Laminin Domain II FAA_hydro_N_2 PF18288.1 KEG09494.1 - 0.13 12.7 0.7 0.4 11.1 0.4 2.1 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Me-amine-dh_H PF06433.11 KEG09494.1 - 0.18 10.6 0.0 0.36 9.7 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DUF3584 PF12128.8 KEG09494.1 - 0.27 8.7 7.2 0.39 8.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prok-RING_4 PF14447.6 KEG09494.1 - 1.2 9.1 4.5 2.4 8.1 4.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Apolipoprotein PF01442.18 KEG09494.1 - 2.2 8.1 12.1 5.7 6.8 11.0 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lipase_3 PF01764.25 KEG09495.1 - 9.5e-14 51.5 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KEG09495.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Poty_coat PF00767.18 KEG09497.1 - 0.095 12.2 0.1 0.096 12.2 0.1 1.1 1 0 0 1 1 1 0 Potyvirus coat protein MBOAT PF03062.19 KEG09498.1 - 0.00013 21.5 1.9 0.00013 21.5 1.9 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Tmemb_40 PF10160.9 KEG09498.1 - 0.12 11.8 4.0 0.16 11.4 3.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein PAP2 PF01569.21 KEG09499.1 - 3.3e-29 101.4 1.2 3.3e-29 101.4 1.2 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KEG09499.1 - 0.013 15.2 13.1 0.84 9.3 13.1 2.8 1 1 0 1 1 1 0 PAP2 superfamily DUF5631 PF18645.1 KEG09501.1 - 0.018 15.4 1.2 6.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5631) MIF4G_like_2 PF09090.11 KEG09501.1 - 0.029 13.8 0.5 0.04 13.4 0.5 1.3 1 0 0 1 1 1 0 MIF4G like DUF724 PF05266.14 KEG09501.1 - 0.058 13.2 1.3 0.16 11.7 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 KEG09501.1 - 0.062 13.5 6.3 0.026 14.8 3.1 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KEG09501.1 - 0.47 9.3 5.5 0.31 9.9 3.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KEG09501.1 - 7 5.9 10.7 3.9 6.7 7.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cation_efflux PF01545.21 KEG09503.1 - 1.5e-33 116.3 1.2 2.8e-33 115.3 0.1 2.0 2 1 0 2 2 2 1 Cation efflux family TMEM190 PF15431.6 KEG09503.1 - 0.26 11.4 1.1 4.9 7.3 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 190 DUF2946 PF11162.8 KEG09503.1 - 2.3 8.9 8.3 28 5.4 7.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) TBP PF00352.21 KEG09504.1 - 1.2e-42 143.7 0.0 7.3e-25 86.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF5102 PF17104.5 KEG09504.1 - 0.22 11.5 0.8 0.34 10.9 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) TPR_8 PF13181.6 KEG09505.1 - 7.2e-06 25.8 3.7 0.0005 20.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09505.1 - 8.9e-05 22.1 6.2 0.0088 15.8 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG09505.1 - 0.00037 20.4 13.3 0.0052 16.8 0.1 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG09505.1 - 0.00056 20.1 0.6 0.91 10.0 0.0 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09505.1 - 0.0024 17.5 0.0 15 5.3 0.0 3.6 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 KEG09505.1 - 0.022 15.3 2.3 6.2 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09505.1 - 0.05 13.9 1.1 0.37 11.1 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat OSCP PF00213.18 KEG09505.1 - 0.068 13.3 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit ANAPC3 PF12895.7 KEG09505.1 - 0.073 13.3 3.3 2.1 8.6 0.1 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KEG09505.1 - 0.088 12.7 1.7 2.1 8.3 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KEG09505.1 - 0.37 11.5 2.4 5.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Sel1 repeat Lipase_3 PF01764.25 KEG09506.1 - 9.7e-23 80.6 0.0 2.5e-22 79.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEG09506.1 - 0.0067 17.1 0.2 0.0096 16.5 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEG09506.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KEG09506.1 - 0.035 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KEG09506.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PE-PPE PF08237.11 KEG09506.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.8 KEG09506.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2770 PF10968.8 KEG09510.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) CECR6_TMEM121 PF14997.6 KEG09514.1 - 1.5e-07 31.5 5.2 1.1e-05 25.3 0.4 2.5 3 0 0 3 3 3 2 CECR6/TMEM121 family SicP-binding PF09119.10 KEG09515.1 - 0.057 13.4 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 SicP binding Myb_DNA-binding PF00249.31 KEG09515.1 - 0.16 12.2 0.0 32 4.8 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain BESS PF02944.20 KEG09516.1 - 0.16 11.8 0.5 0.7 9.8 0.3 2.1 2 0 0 2 2 2 0 BESS motif Choline_kinase PF01633.20 KEG09518.1 - 4.9e-30 104.7 0.0 1.7e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KEG09518.1 - 9.8e-11 42.0 0.3 5.5e-08 33.0 0.1 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family HA2 PF04408.23 KEG09519.1 - 1.5e-22 79.9 0.1 1.2e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEG09519.1 - 1.4e-15 57.6 0.0 3.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KEG09519.1 - 2.1e-15 56.8 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KEG09519.1 - 1.3e-06 28.3 0.1 7.5e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEG09519.1 - 2e-06 28.1 0.0 5.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG09519.1 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEG09519.1 - 0.0028 17.2 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KEG09519.1 - 0.0037 16.3 0.0 0.0088 15.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KEG09519.1 - 0.0072 16.3 0.1 6.6 6.7 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEG09519.1 - 0.016 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG09519.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KEG09519.1 - 0.029 14.9 0.1 0.62 10.6 0.1 2.4 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KEG09519.1 - 0.052 13.0 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein GIT_SHD PF08518.11 KEG09519.1 - 0.15 11.7 0.1 0.61 9.8 0.1 2.2 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT DUF2075 PF09848.9 KEG09519.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Armet PF10208.9 KEG09520.1 - 3.9e-07 30.1 0.1 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 KEG09520.1 - 0.017 14.9 0.0 0.058 13.2 0.0 2.0 2 0 0 2 2 2 0 SAP domain MBOAT PF03062.19 KEG09522.1 - 3.3e-16 59.6 12.9 3.3e-16 59.6 12.9 2.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 KEG09524.1 - 2.6e-32 112.6 21.5 7.3e-32 111.1 21.6 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 KEG09525.1 - 3.1e-30 105.7 22.5 3.1e-30 105.7 22.5 2.2 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF4064 PF13273.6 KEG09525.1 - 0.052 13.8 1.0 0.43 10.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Pkinase PF00069.25 KEG09527.1 - 5.6e-21 75.1 0.2 1.3e-08 34.5 0.0 5.1 5 1 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09527.1 - 4.5e-11 42.5 0.0 0.028 13.7 0.0 4.2 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG09527.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SUIM_assoc PF16619.5 KEG09528.1 - 0.0077 16.3 2.8 0.014 15.4 2.8 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG09528.1 - 0.5 9.9 6.2 0.51 9.9 6.2 1.1 1 0 0 1 1 1 0 Spt20 family Na_H_Exchanger PF00999.21 KEG09529.1 - 9.5e-16 57.6 26.6 9.5e-16 57.6 26.6 1.8 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family QRPTase_C PF01729.19 KEG09530.1 - 0.094 12.5 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Chordopox_A33R PF05966.12 KEG09533.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Seryl_tRNA_N PF02403.22 KEG09533.1 - 1.7 8.9 24.4 0.18 12.0 3.5 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GSCFA PF08885.11 KEG09533.1 - 1.7 8.3 4.0 1.3 8.6 0.5 2.2 2 0 0 2 2 2 0 GSCFA family TMCO5 PF14992.6 KEG09533.1 - 2.2 7.8 15.3 0.39 10.3 7.7 2.3 2 0 0 2 2 2 0 TMCO5 family Rnk_N PF14760.6 KEG09533.1 - 4.7 7.8 7.0 1 9.9 2.0 2.6 2 0 0 2 2 2 0 Rnk N-terminus DUF1843 PF08898.10 KEG09533.1 - 6.1 7.4 14.5 2.8 8.5 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) MCR_gamma PF02240.16 KEG09534.1 - 0.12 11.6 0.4 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Methyl-coenzyme M reductase gamma subunit Methyltransf_16 PF10294.9 KEG09535.1 - 1.4e-09 37.9 0.0 1.4e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 KEG09535.1 - 2.9e-05 23.7 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KEG09535.1 - 0.0014 19.3 0.0 0.0043 17.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG09535.1 - 0.0098 16.6 0.0 0.046 14.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Abhydrolase_6 PF12697.7 KEG09537.1 - 1.5e-16 61.7 0.2 1.8e-16 61.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEG09537.1 - 3.1e-11 43.0 0.0 4.3e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG09537.1 - 1.1e-07 31.8 0.0 3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 KEG09537.1 - 3.8e-05 23.1 0.0 0.00066 19.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 KEG09537.1 - 0.055 13.1 0.0 11 5.6 0.1 2.7 1 1 1 2 2 2 0 Serine hydrolase (FSH1) DUF676 PF05057.14 KEG09537.1 - 0.065 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 KEG09537.1 - 0.071 13.0 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Serine hydrolase 4HBT PF03061.22 KEG09538.1 - 1.8e-05 25.0 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KEG09538.1 - 0.00018 21.9 1.8 0.00021 21.6 0.3 1.8 1 1 1 2 2 2 1 Thioesterase-like superfamily VacA2 PF03077.14 KEG09538.1 - 0.0072 16.1 2.2 0.015 15.2 2.2 1.5 1 0 0 1 1 1 1 Putative vacuolating cytotoxin SKA2 PF16740.5 KEG09538.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 RRM_1 PF00076.22 KEG09539.1 - 1.1e-16 60.4 0.0 1.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09539.1 - 0.0001 21.9 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG09539.1 - 0.026 14.6 0.0 0.046 13.8 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif Glutaredoxin PF00462.24 KEG09540.1 - 0.00011 22.4 0.1 0.00054 20.1 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 KEG09540.1 - 0.0017 18.7 0.2 0.0055 17.1 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEG09540.1 - 0.17 12.2 0.2 0.51 10.7 0.2 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RRM_1 PF00076.22 KEG09542.1 - 1.1e-15 57.1 0.1 3.4e-15 55.6 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 PF09849.9 KEG09542.1 - 0.0044 17.1 26.9 0.0055 16.8 26.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 KEG09542.1 - 0.0049 16.9 20.9 0.0054 16.8 20.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 KEG09542.1 - 0.0057 16.6 6.3 0.0066 16.4 6.3 1.0 1 0 0 1 1 1 1 SPX domain PAT1 PF09770.9 KEG09542.1 - 0.02 13.2 13.9 0.022 13.1 13.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLC12 PF03522.15 KEG09542.1 - 0.052 12.6 3.0 0.058 12.4 3.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 EPL1 PF10513.9 KEG09542.1 - 0.063 13.7 2.8 0.079 13.4 2.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Lin-8 PF03353.15 KEG09542.1 - 1.3 8.5 11.8 1.8 8.1 11.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 KEG09542.1 - 1.7 7.2 7.1 1.9 7.1 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPSF100_C PF13299.6 KEG09542.1 - 1.9 8.6 7.5 6.3 7.0 7.5 1.8 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 KEG09542.1 - 2.2 8.9 17.5 3.6 8.2 17.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.6 KEG09542.1 - 4.8 6.4 7.5 6.4 6.0 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ANAPC_CDC26 PF10471.9 KEG09542.1 - 5.7 7.9 30.8 5.4 7.9 22.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Presenilin PF01080.17 KEG09542.1 - 8.1 5.1 9.2 9.9 4.8 9.2 1.1 1 0 0 1 1 1 0 Presenilin adh_short PF00106.25 KEG09544.1 - 9.8e-22 77.4 0.3 2e-21 76.4 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG09544.1 - 1.7e-11 44.2 0.2 3e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG09544.1 - 2.2e-09 37.5 0.4 3.7e-09 36.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEG09544.1 - 0.0026 17.3 0.1 0.004 16.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KEG09544.1 - 0.021 14.2 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KEG09544.1 - 0.021 15.2 0.1 0.055 13.9 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KEG09544.1 - 0.035 13.3 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEG09544.1 - 0.081 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dmrt1 PF12374.8 KEG09544.1 - 0.096 13.1 1.6 0.27 11.7 1.6 1.7 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 THF_DHG_CYH_C PF02882.19 KEG09544.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.27 KEG09544.1 - 0.14 12.7 0.2 0.27 11.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG09544.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KEG09545.1 - 1.1e-22 80.5 0.0 2.9e-21 75.8 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG09545.1 - 6.6e-13 48.8 0.0 2.6e-12 46.8 0.0 2.0 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG09545.1 - 5.3e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEG09545.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEG09545.1 - 0.0028 17.1 0.0 0.0057 16.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEG09545.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Oxidored_nitro PF00148.19 KEG09545.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Abhydrolase_2 PF02230.16 KEG09547.1 - 8e-41 140.2 0.0 1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KEG09547.1 - 1.5e-06 27.6 0.3 0.0031 16.8 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEG09547.1 - 0.00019 21.0 0.0 0.099 12.1 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 KEG09547.1 - 0.0024 17.5 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KEG09547.1 - 0.013 16.1 1.1 0.025 15.2 1.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KEG09547.1 - 0.017 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2920 PF11144.8 KEG09547.1 - 0.25 10.5 0.3 12 4.9 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) ThiF PF00899.21 KEG09550.1 - 4e-93 311.3 0.1 9.5e-63 211.8 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KEG09550.1 - 4.1e-67 226.7 0.0 5.9e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KEG09550.1 - 5.3e-07 30.2 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KEG09550.1 - 0.00039 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 KEG09550.1 - 0.0029 17.7 0.5 3.1 7.9 0.0 3.4 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase E1_FCCH PF16190.5 KEG09550.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Lactamase_B PF00753.27 KEG09551.1 - 2.4e-12 47.3 0.0 3.4e-11 43.5 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta-Casp PF10996.8 KEG09551.1 - 0.11 12.7 0.1 22 5.4 0.0 2.6 3 0 0 3 3 3 0 Beta-Casp domain Kelch_5 PF13854.6 KEG09552.1 - 5.4e-13 48.6 1.6 0.00046 20.1 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KEG09552.1 - 1.2e-10 41.2 0.3 0.019 14.9 0.0 4.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG09552.1 - 4.4e-06 26.8 1.4 1.5 9.2 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KEG09552.1 - 8.2e-05 22.4 0.4 0.079 13.0 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KEG09552.1 - 0.078 13.3 13.7 0.36 11.2 0.0 6.1 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG09552.1 - 0.85 9.3 4.8 7.4 6.2 0.0 4.1 4 0 0 4 4 4 0 Kelch motif RecC_C PF17946.1 KEG09553.1 - 0.045 13.5 0.7 0.098 12.4 0.7 1.5 1 0 0 1 1 1 0 RecC C-terminal domain Mito_carr PF00153.27 KEG09554.1 - 5.6e-09 35.8 0.1 5.5e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial carrier protein API5 PF05918.11 KEG09556.1 - 5.2e-06 25.6 0.0 0.072 11.9 0.0 2.3 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) Carn_acyltransf PF00755.20 KEG09557.1 - 2.6e-161 538.2 0.0 2.9e-161 538.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.13 KEG09558.1 - 5.8e-10 39.6 0.0 1.5e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 SEP domain DAO_C PF16901.5 KEG09558.1 - 0.2 11.6 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase DUF667 PF05018.13 KEG09561.1 - 7e-90 299.7 0.1 8.2e-90 299.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) SUIM_assoc PF16619.5 KEG09561.1 - 0.03 14.4 6.5 0.053 13.6 6.5 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RPAP2_Rtr1 PF04181.13 KEG09562.1 - 4.2e-12 46.2 0.0 7.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CCDC92 PF14916.6 KEG09563.1 - 0.00089 19.0 1.8 0.00089 19.0 1.8 3.3 4 0 0 4 4 4 1 Coiled-coil domain of unknown function SUIM_assoc PF16619.5 KEG09563.1 - 0.0078 16.3 22.5 0.068 13.3 8.1 2.7 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2623 PF11115.8 KEG09563.1 - 0.022 14.8 0.4 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) ProSAAS PF07259.12 KEG09563.1 - 6.4 6.7 10.6 0.09 12.7 2.7 1.9 1 1 2 3 3 3 0 ProSAAS precursor MCU PF04678.13 KEG09564.1 - 7e-19 68.6 0.1 7e-19 68.6 0.1 1.3 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Peptidase_M16 PF00675.20 KEG09565.1 - 1.3e-09 38.1 0.0 3.3e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Vps51 PF08700.11 KEG09566.1 - 4.9e-26 90.6 3.7 1.3e-24 86.1 1.5 3.0 3 0 0 3 3 2 1 Vps51/Vps67 Sec5 PF15469.6 KEG09566.1 - 2.5e-08 33.9 0.1 6.4e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 KEG09566.1 - 1.4e-07 31.6 3.1 2e-07 31.2 1.5 2.0 2 0 0 2 2 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.12 KEG09566.1 - 2e-07 30.0 1.2 4.1e-07 29.0 1.2 1.5 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.12 KEG09566.1 - 4.9e-07 29.1 1.5 9.2e-07 28.1 1.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal COG5 PF10392.9 KEG09566.1 - 1.6e-06 28.3 2.3 1.6e-06 28.3 2.3 2.2 3 0 0 3 3 1 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 KEG09566.1 - 0.00028 20.3 3.3 0.00052 19.4 3.3 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KEG09566.1 - 0.0039 15.8 1.5 0.0064 15.1 1.5 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 NPV_P10 PF05531.12 KEG09566.1 - 0.015 15.8 1.0 0.085 13.3 0.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 KEG09566.1 - 0.015 15.4 1.2 0.047 13.9 1.2 1.8 1 0 0 1 1 1 0 Haemolysin XhlA BLOC1_2 PF10046.9 KEG09566.1 - 0.019 15.2 1.3 0.095 13.0 1.3 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 KEG09566.1 - 0.023 14.1 0.8 0.051 12.9 0.4 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KEG09566.1 - 0.029 14.4 6.5 0.062 13.3 1.8 3.0 3 0 0 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 KEG09566.1 - 0.033 14.2 1.1 0.14 12.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KEG09566.1 - 0.043 13.9 2.1 0.11 12.5 2.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 KEG09566.1 - 0.053 13.9 1.9 0.57 10.6 1.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.10 KEG09566.1 - 0.073 13.2 1.0 0.29 11.3 1.0 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Smoothelin PF12510.8 KEG09566.1 - 0.1 12.7 0.7 0.35 10.9 0.7 1.9 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein GCN5L1 PF06320.13 KEG09566.1 - 0.14 12.3 0.6 5.1 7.3 0.0 3.2 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) RIH_assoc PF08454.11 KEG09566.1 - 0.16 11.8 1.3 6.2 6.7 0.3 3.3 3 0 0 3 3 3 0 RyR and IP3R Homology associated Occludin_ELL PF07303.13 KEG09566.1 - 0.2 12.4 0.2 1 10.2 0.1 2.3 2 0 0 2 2 1 0 Occludin homology domain FlgN PF05130.12 KEG09566.1 - 0.34 11.4 6.4 0.056 14.0 1.4 2.3 3 0 0 3 3 1 0 FlgN protein ZapB PF06005.12 KEG09566.1 - 0.66 10.5 2.8 1.1 9.8 0.1 2.7 2 1 1 3 3 2 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 KEG09566.1 - 1.7 8.7 6.0 1.1 9.4 0.5 3.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NepR PF18557.1 KEG09566.1 - 1.9 8.2 5.5 2.1 8.0 0.3 3.1 3 0 0 3 3 3 0 Anti-sigma factor NepR zf-U1 PF06220.12 KEG09567.1 - 1.7e-06 27.7 1.3 4.2e-06 26.4 0.4 2.1 2 0 0 2 2 2 1 U1 zinc finger Mito_carr PF00153.27 KEG09569.1 - 3.3e-52 174.4 6.0 1.5e-23 82.6 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FATC PF02260.20 KEG09569.1 - 0.21 11.5 0.6 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 FATC domain TPT PF03151.16 KEG09571.1 - 6.9e-11 42.0 21.8 8.5e-11 41.7 21.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEG09571.1 - 0.0002 21.5 33.1 0.0028 17.8 15.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family DNA_pol_A_exo1 PF01612.20 KEG09572.1 - 2.9e-39 134.6 0.2 4.8e-39 133.9 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KEG09572.1 - 3.1e-17 63.0 0.0 9.7e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KEG09572.1 - 8.6e-09 35.3 0.1 4.1e-08 33.1 0.0 2.2 3 0 0 3 3 3 1 HRDC domain PSI PF01437.25 KEG09573.1 - 0.025 15.1 4.2 0.025 15.1 4.2 2.4 2 0 0 2 2 2 0 Plexin repeat PIP5K PF01504.18 KEG09574.1 - 5.3e-72 242.3 0.0 8e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cyt-b5 PF00173.28 KEG09576.1 - 1.9e-07 31.1 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CLZ PF16526.5 KEG09577.1 - 1.2 9.5 13.3 0.63 10.4 1.7 4.0 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 KEG09577.1 - 4.5 6.8 14.8 1.9 8.0 5.9 2.9 3 0 0 3 3 3 0 fzo-like conserved region Pkinase PF00069.25 KEG09578.1 - 4.6e-48 163.9 0.0 6.9e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09578.1 - 1.9e-18 66.7 0.1 1.2e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEG09578.1 - 4.1e-06 26.9 0.6 0.019 14.9 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.8 KEG09578.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 KEG09578.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PP2C PF00481.21 KEG09579.1 - 7.8e-66 222.3 0.0 7.8e-66 222.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KEG09579.1 - 0.00018 21.5 0.3 0.41 10.5 0.0 2.7 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEG09579.1 - 0.0018 17.9 0.0 0.0045 16.6 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C HJURP_C PF12347.8 KEG09579.1 - 1.1 9.3 3.6 1.1 9.3 1.7 2.0 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat BROMI PF14961.6 KEG09579.1 - 4.3 4.6 8.5 7.2 3.9 8.5 1.3 1 0 0 1 1 1 0 Broad-minded protein WD40 PF00400.32 KEG09580.1 - 5.4e-07 30.2 11.0 0.097 13.6 0.2 4.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2415 PF10313.9 KEG09580.1 - 0.025 14.5 0.2 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) tify PF06200.14 KEG09580.1 - 0.17 11.2 0.1 0.34 10.3 0.1 1.4 1 0 0 1 1 1 0 tify domain DEAD PF00270.29 KEG09581.1 - 2.5e-37 128.3 0.2 1.2e-36 126.1 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG09581.1 - 3.6e-25 88.5 1.3 1.8e-24 86.2 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG09581.1 - 1.6e-08 34.8 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KEG09581.1 - 0.00023 20.6 1.9 0.00086 18.7 0.0 2.6 4 0 0 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit DUF3549 PF12069.8 KEG09581.1 - 0.0084 15.2 0.2 0.019 14.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) DUF4844 PF16133.5 KEG09581.1 - 0.015 15.9 1.0 0.033 14.7 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Choline_transpo PF04515.12 KEG09583.1 - 6.7e-75 252.3 45.2 6.7e-75 252.3 45.2 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter LETM1 PF07766.13 KEG09584.1 - 6.9e-06 25.6 0.0 2.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 LETM1-like protein GST_C_6 PF17171.4 KEG09585.1 - 7.4e-07 28.9 0.0 1.9e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KEG09585.1 - 0.00034 21.3 0.0 0.00089 20.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KEG09585.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Chordopox_A20R PF05941.13 KEG09585.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A20R protein Pkinase PF00069.25 KEG09589.1 - 5.9e-41 140.6 0.0 3.8e-39 134.6 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09589.1 - 5.7e-20 71.7 0.0 2.9e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG09589.1 - 0.038 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG09589.1 - 0.064 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEG09589.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.9 KEG09590.1 - 0.13 11.9 3.4 0.21 11.2 3.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3235 PF11574.8 KEG09592.1 - 0.08 13.8 3.9 0.27 12.1 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) CRCB PF02537.15 KEG09593.1 - 9.1e-31 106.0 22.0 5e-17 62.0 4.6 2.6 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Phage_holin_3_1 PF05106.12 KEG09593.1 - 0.04 14.3 2.9 0.45 11.0 0.4 2.6 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) RNA_pol_Rpb1_1 PF04997.12 KEG09594.1 - 1.9e-95 319.8 0.1 7e-95 317.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KEG09594.1 - 2.5e-94 315.7 0.1 3.9e-94 315.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEG09594.1 - 5.9e-70 234.8 1.0 1.2e-69 233.8 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KEG09594.1 - 1.8e-48 164.9 0.9 3.4e-48 164.0 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KEG09594.1 - 4.4e-41 140.4 0.0 1.1e-40 139.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEG09594.1 - 7.4e-26 90.2 0.1 1.9e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 KEG09594.1 - 9.3e-22 77.5 0.7 9.3e-22 77.5 0.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.12 KEG09594.1 - 0.13 11.8 3.2 0.27 10.8 3.2 1.4 1 0 0 1 1 1 0 PspA/IM30 family RLL PF10036.9 KEG09594.1 - 0.43 10.4 2.2 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Phage_GP20 PF06810.11 KEG09595.1 - 0.031 14.1 0.7 0.12 12.2 0.4 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 FAM76 PF16046.5 KEG09595.1 - 0.08 12.3 3.9 0.14 11.5 3.9 1.3 1 0 0 1 1 1 0 FAM76 protein DUF294_C PF10335.9 KEG09595.1 - 0.57 10.0 10.7 0.54 10.0 2.3 2.8 2 1 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Phage_Mu_Gam PF07352.12 KEG09595.1 - 0.83 9.6 7.2 0.21 11.5 2.5 2.4 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein HsbA PF12296.8 KEG09595.1 - 6.2 7.3 6.2 8.1 6.9 0.2 3.0 3 0 0 3 3 3 0 Hydrophobic surface binding protein A OmpH PF03938.14 KEG09595.1 - 7.2 6.9 21.5 13 6.2 0.8 3.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) 5-FTHF_cyc-lig PF01812.20 KEG09595.1 - 8.2 6.2 8.0 1.7 8.4 2.5 2.4 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family Calreticulin PF00262.18 KEG09596.1 - 4.7e-96 321.8 37.6 1.7e-62 211.4 6.0 3.1 1 1 2 3 3 3 3 Calreticulin family DUF4816 PF16086.5 KEG09596.1 - 7.4 6.6 10.3 21 5.1 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) TerD PF02342.18 KEG09597.1 - 0.018 14.5 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 TerD domain Adenylsucc_synt PF00709.21 KEG09598.1 - 1.4e-86 291.1 0.0 1.7e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase EphA2_TM PF14575.6 KEG09599.1 - 0.046 14.6 0.0 0.096 13.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MHYT PF03707.16 KEG09599.1 - 0.15 12.2 1.0 0.27 11.4 1.0 1.4 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Cadherin_C_2 PF16492.5 KEG09599.1 - 0.18 12.5 0.0 0.33 11.7 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Laminin_G_1 PF00054.23 KEG09599.1 - 1.3 9.2 7.0 6.2 7.1 0.2 3.1 2 1 1 3 3 3 0 Laminin G domain Nucleoside_tran PF01733.18 KEG09601.1 - 4e-27 95.4 6.5 4e-27 95.4 6.5 1.6 2 0 0 2 2 2 1 Nucleoside transporter Ribosomal_S4e PF00900.20 KEG09602.1 - 1.9e-26 91.8 0.2 3.4e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KEG09602.1 - 1.8e-17 62.7 0.0 3.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KEG09602.1 - 2.8e-17 62.5 3.4 8.4e-17 61.0 3.4 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KEG09602.1 - 1.3e-09 37.6 0.0 3.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KEG09602.1 - 3.3e-06 26.9 0.1 1.6e-05 24.7 0.1 2.2 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 KEG09602.1 - 0.16 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein TPK_catalytic PF04263.16 KEG09603.1 - 2.6e-11 43.6 0.0 3e-05 24.1 0.0 2.9 2 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KEG09603.1 - 1.7e-10 40.5 0.0 4.1e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Claudin_3 PF06653.11 KEG09604.1 - 0.0084 16.1 0.4 0.026 14.5 0.1 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like MHYT PF03707.16 KEG09604.1 - 0.016 15.4 2.0 0.9 9.7 0.2 2.3 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat EphA2_TM PF14575.6 KEG09604.1 - 0.033 15.1 0.3 0.13 13.2 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2154 PF09922.9 KEG09604.1 - 0.04 13.8 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF LEP503 PF15221.6 KEG09604.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 MAP17 PF15807.5 KEG09604.1 - 0.46 10.7 1.6 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Baculo_PEP_C PF04513.12 KEG09605.1 - 2.5 8.2 18.8 0.15 12.1 0.2 4.9 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KEG09605.1 - 7.3 5.9 51.9 0.04 13.3 12.2 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) AAA_22 PF13401.6 KEG09605.1 - 8.7 6.6 10.5 0.15 12.3 0.7 2.9 3 1 0 3 3 3 0 AAA domain AMPKBI PF04739.15 KEG09607.1 - 1.8e-14 53.7 0.8 4.9e-14 52.4 0.8 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KEG09607.1 - 6.4e-07 29.5 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Dicistro_VP4 PF11492.8 KEG09608.1 - 7 6.7 11.9 4.4 7.3 0.0 3.3 3 1 0 3 3 3 0 Cricket paralysis virus, VP4 Steroid_dh PF02544.16 KEG09610.1 - 9.9e-37 126.2 0.7 2e-36 125.2 0.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEG09610.1 - 1.8e-06 27.6 0.4 3.8e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) SET PF00856.28 KEG09612.1 - 4.1e-15 56.6 0.0 1.4e-14 54.9 0.0 1.8 1 1 0 1 1 1 1 SET domain FtsJ PF01728.19 KEG09613.1 - 1.1e-44 152.7 0.2 1.3e-44 152.4 0.2 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KEG09613.1 - 7e-06 26.0 0.0 2e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG09613.1 - 0.0024 18.5 0.2 0.0045 17.7 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG09613.1 - 0.0099 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NSP16 PF06460.12 KEG09613.1 - 0.058 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 cNMP_binding PF00027.29 KEG09615.1 - 0.0042 17.1 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Secretin_N PF03958.17 KEG09616.1 - 0.07 13.5 0.6 28 5.2 0.0 3.7 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain TFIIB_C_1 PF18542.1 KEG09617.1 - 2.1e-41 139.9 0.8 4.9e-41 138.7 0.8 1.7 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 TF_Zn_Ribbon PF08271.12 KEG09617.1 - 0.0003 20.3 1.0 0.0003 20.3 1.0 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 KEG09617.1 - 0.005 17.2 0.1 0.015 15.6 0.1 1.8 1 0 0 1 1 1 1 Restriction alleviation protein Lar ubiquitin PF00240.23 KEG09619.1 - 1.3e-05 24.8 0.0 0.0002 21.1 0.0 2.6 2 1 1 3 3 3 1 Ubiquitin family CENP-F_leu_zip PF10473.9 KEG09619.1 - 0.15 12.1 0.2 0.25 11.4 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tho1_MOS11_C PF18592.1 KEG09620.1 - 0.013 15.3 0.0 0.74 9.7 0.0 2.8 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Adhesin_P1_N PF18652.1 KEG09620.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain Lipase_3 PF01764.25 KEG09621.1 - 2.3e-17 63.2 0.0 8.2e-17 61.4 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEG09621.1 - 0.00015 22.5 0.2 0.00015 22.5 0.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEG09621.1 - 0.00054 19.8 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KEG09621.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KEG09621.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KEG09621.1 - 0.12 11.6 0.1 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase PF00151.19 KEG09621.1 - 0.16 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipase SET PF00856.28 KEG09622.1 - 2e-07 31.6 0.0 9.5e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF4936 PF16290.5 KEG09625.1 - 3.8 8.3 5.4 4.8 7.9 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4936) UPF0020 PF01170.18 KEG09626.1 - 2.7e-21 76.1 0.0 9.1e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KEG09626.1 - 0.0028 18.3 0.0 0.06 14.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG09626.1 - 0.0047 17.5 0.0 0.016 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KEG09626.1 - 0.008 15.7 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 RRNA methyltransferase AviRa THUMP PF02926.17 KEG09626.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 THUMP domain N6_N4_Mtase PF01555.18 KEG09626.1 - 0.3 10.8 0.0 0.56 9.9 0.0 1.3 1 0 0 1 1 1 0 DNA methylase PCSK9_C1 PF18459.1 KEG09627.1 - 0.011 15.8 0.7 0.03 14.5 0.7 1.7 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Hydrolase_6 PF13344.6 KEG09627.1 - 0.028 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CsoS2_M PF12288.8 KEG09627.1 - 0.13 11.7 0.3 0.22 10.9 0.3 1.4 1 1 0 1 1 1 0 Carboxysome shell peptide mid-region ODV-E18 PF10717.9 KEG09627.1 - 0.14 12.0 0.2 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 R3H-assoc PF13902.6 KEG09630.1 - 6e-18 65.5 0.7 1.2e-17 64.5 0.1 1.8 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 KEG09630.1 - 0.039 13.9 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 R3H domain LRR_4 PF12799.7 KEG09631.1 - 5.2e-05 23.5 0.2 3.6 8.1 0.0 4.9 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) CALCOCO1 PF07888.11 KEG09631.1 - 0.0061 15.5 5.6 0.012 14.5 5.6 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 KEG09631.1 - 0.0091 16.6 5.9 0.023 15.3 5.9 1.7 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Fez1 PF06818.15 KEG09631.1 - 0.013 16.0 4.3 0.027 14.9 3.0 2.0 2 0 0 2 2 2 0 Fez1 HSCB_C PF07743.13 KEG09631.1 - 0.13 12.8 1.5 0.46 11.0 1.5 2.0 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain bZIP_2 PF07716.15 KEG09631.1 - 0.31 11.2 3.1 1.1 9.4 3.1 1.9 1 0 0 1 1 1 0 Basic region leucine zipper LRR_1 PF00560.33 KEG09631.1 - 0.42 11.3 1.7 40 5.3 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DSPc PF00782.20 KEG09633.1 - 1.1e-12 48.0 0.1 1.9e-11 43.9 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG09633.1 - 0.0091 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DER1 PF04511.15 KEG09635.1 - 7.7e-33 114.0 3.7 9.1e-33 113.8 3.7 1.0 1 0 0 1 1 1 1 Der1-like family Arm-DNA-bind_3 PF13356.6 KEG09635.1 - 0.021 15.2 0.2 0.049 14.0 0.2 1.6 1 1 0 1 1 1 0 Arm DNA-binding domain DUF485 PF04341.12 KEG09635.1 - 0.85 9.6 5.8 0.11 12.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Pkinase PF00069.25 KEG09636.1 - 1.5e-55 188.4 0.0 2.4e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09636.1 - 1.7e-37 129.2 0.0 1.6e-35 122.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG09636.1 - 0.0055 16.1 0.1 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like zf-MYND PF01753.18 KEG09637.1 - 5.3e-07 29.6 12.1 1.3e-06 28.4 12.1 1.7 1 0 0 1 1 1 1 MYND finger CRA_rpt PF07046.11 KEG09638.1 - 5.4e-16 58.5 704.1 0.00032 20.8 31.7 29.9 2 2 27 29 29 29 17 Cytoplasmic repetitive antigen (CRA) like repeat Piwi PF02171.17 KEG09639.1 - 5e-13 49.0 0.0 1.3e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.22 KEG09639.1 - 1.5e-07 31.3 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KEG09639.1 - 7.4e-05 23.0 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain Thioredoxin_15 PF18403.1 KEG09639.1 - 0.0033 17.4 0.4 0.038 13.9 0.0 2.5 3 1 0 3 3 3 1 Thioredoxin-like domain MID_pPIWI_RE PF18157.1 KEG09639.1 - 0.0072 16.6 0.0 0.03 14.6 0.0 1.9 1 1 1 2 2 2 1 MID domain of pPIWI_RE DUF2889 PF11136.8 KEG09639.1 - 0.13 12.6 0.2 0.31 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) Prok-RING_4 PF14447.6 KEG09640.1 - 0.00062 19.6 0.2 0.00062 19.6 0.2 6.1 5 1 1 6 6 6 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEG09640.1 - 0.0025 18.1 0.2 0.0025 18.1 0.2 6.9 4 1 2 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 KEG09641.1 - 0.00017 21.5 2.7 0.0073 16.2 0.0 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG09641.1 - 0.0005 20.0 0.1 0.0005 20.0 0.1 2.3 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KEG09641.1 - 0.0043 16.9 5.5 0.011 15.5 0.5 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEG09641.1 - 0.0053 16.6 7.9 0.19 11.6 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG09641.1 - 0.0098 15.8 7.0 0.015 15.2 1.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG09641.1 - 0.056 13.8 0.3 0.056 13.8 0.3 2.9 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 KEG09641.1 - 0.22 11.4 0.2 0.22 11.4 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_SprT PF17283.2 KEG09641.1 - 4 7.4 6.1 3.1 7.8 0.4 2.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Mpv17_PMP22 PF04117.12 KEG09642.1 - 8.6e-11 41.9 1.3 8.6e-11 41.9 1.3 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family ABC2_membrane_3 PF12698.7 KEG09643.1 - 4.3e-61 206.9 43.5 7.1e-41 140.5 14.8 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KEG09643.1 - 5.6e-54 182.4 0.0 2e-26 93.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEG09643.1 - 7.1e-15 55.6 3.8 2.2e-05 24.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG09643.1 - 3.6e-05 23.3 0.0 0.23 10.9 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEG09643.1 - 6.2e-05 23.6 0.4 0.12 12.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEG09643.1 - 0.0015 18.5 0.2 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 KEG09643.1 - 0.0028 17.3 1.4 1.8 8.1 0.1 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KEG09643.1 - 0.0034 17.6 2.3 0.86 9.9 0.1 3.9 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KEG09643.1 - 0.0088 15.8 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEG09643.1 - 0.01 15.6 0.3 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4162 PF13732.6 KEG09643.1 - 0.033 14.9 0.0 15 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) MukB PF04310.12 KEG09643.1 - 0.046 13.5 0.6 7.8 6.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_15 PF13175.6 KEG09643.1 - 0.054 13.2 0.1 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain DLIC PF05783.11 KEG09643.1 - 0.17 10.7 0.1 0.42 9.4 0.0 1.6 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PHO4 PF01384.20 KEG09643.1 - 0.23 10.5 3.9 9.7 5.1 4.2 2.5 1 1 0 1 1 1 0 Phosphate transporter family AAA_13 PF13166.6 KEG09643.1 - 0.42 9.2 1.8 4.8 5.7 0.1 2.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KEG09643.1 - 0.63 10.1 2.5 2.2 8.3 0.1 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain DUF1489 PF07370.11 KEG09644.1 - 0.066 12.9 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) SLAIN PF15301.6 KEG09646.1 - 0.065 12.5 0.6 0.11 11.8 0.6 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family TMEM71 PF15121.6 KEG09646.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 TMEM71 protein family Torus PF16131.5 KEG09647.1 - 0.96 10.2 7.2 0.25 12.1 2.3 2.6 2 0 0 2 2 2 0 Torus domain Kinesin_assoc PF16183.5 KEG09650.1 - 0.06 13.5 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Kinesin-associated HTH_33 PF13592.6 KEG09650.1 - 0.14 11.8 0.3 6.7 6.4 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix AAA_13 PF13166.6 KEG09650.1 - 0.19 10.4 0.5 0.29 9.7 0.5 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEG09651.1 - 9.6e-39 132.8 1.0 2.2e-38 131.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEG09651.1 - 5.2e-18 64.7 1.5 4.3e-17 61.8 1.6 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEG09651.1 - 9.5e-13 47.7 0.4 2e-12 46.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEG09651.1 - 9.5e-07 29.3 0.9 0.0027 18.1 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KEG09651.1 - 8e-06 25.9 0.7 0.00011 22.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG09651.1 - 0.00022 21.0 0.1 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEG09651.1 - 0.00029 21.0 0.0 0.0018 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEG09651.1 - 0.0021 18.4 4.0 0.21 11.9 0.1 3.0 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 KEG09651.1 - 0.0033 16.6 0.0 0.0082 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KEG09651.1 - 0.0063 16.7 2.0 0.018 15.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KEG09651.1 - 0.0085 15.5 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Bacillus_HBL PF05791.11 KEG09651.1 - 0.013 15.3 2.0 0.031 14.1 1.8 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) AAA_24 PF13479.6 KEG09651.1 - 0.014 15.1 0.0 0.065 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain CCDC74_C PF14917.6 KEG09651.1 - 0.016 15.7 1.1 0.035 14.6 1.1 1.5 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal CPT PF07931.12 KEG09651.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KEG09651.1 - 0.023 14.0 2.3 0.19 11.1 0.0 2.8 4 0 0 4 4 3 0 KaiC AAA_18 PF13238.6 KEG09651.1 - 0.044 14.3 0.2 0.37 11.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KEG09651.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEG09651.1 - 0.054 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KEG09651.1 - 0.063 12.7 0.7 0.4 10.1 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein IstB_IS21 PF01695.17 KEG09651.1 - 0.064 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KEG09651.1 - 0.065 13.6 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 KEG09651.1 - 0.082 12.2 1.3 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KEG09651.1 - 0.086 12.5 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KEG09651.1 - 0.096 12.6 0.1 0.62 10.0 0.1 2.2 1 1 1 2 2 2 0 NACHT domain Spc24 PF08286.11 KEG09651.1 - 0.099 12.9 2.9 0.26 11.5 2.9 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TsaE PF02367.17 KEG09651.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM3AP_GANP PF16769.5 KEG09651.1 - 0.16 10.2 3.3 0.22 9.7 3.3 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP APG6_N PF17675.1 KEG09651.1 - 0.18 12.3 6.4 0.44 11.1 6.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region LCD1 PF09798.9 KEG09651.1 - 0.39 9.2 5.3 0.57 8.6 5.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF572 PF04502.13 KEG09651.1 - 0.63 9.6 5.2 0.93 9.1 5.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 KEG09651.1 - 1.9 6.3 5.1 2.6 5.8 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zinc_ribbon_2 PF13240.6 KEG09652.1 - 0.035 13.8 3.8 0.064 13.0 3.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HALZ PF02183.18 KEG09652.1 - 0.069 13.4 31.8 0.57 10.4 1.4 6.7 6 1 0 6 6 6 0 Homeobox associated leucine zipper DUF2321 PF10083.9 KEG09652.1 - 0.21 11.2 1.4 0.65 9.6 0.7 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DZR PF12773.7 KEG09652.1 - 0.49 10.5 6.5 0.95 9.5 6.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 KEG09652.1 - 0.95 8.8 7.4 2 7.8 7.4 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Archaeal_AmoA PF12942.7 KEG09653.1 - 0.18 11.5 1.4 0.26 11.0 1.4 1.1 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) TFIIA PF03153.13 KEG09653.1 - 7.2 6.5 16.1 8.8 6.2 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chi-conotoxin PF16981.5 KEG09654.1 - 0.36 11.1 2.9 9.9 6.5 0.2 3.5 2 1 0 2 2 2 0 chi-Conotoxin or t superfamily Helicase_C PF00271.31 KEG09655.1 - 5.6e-14 52.4 0.0 1.7e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KEG09655.1 - 7.7e-13 48.7 1.7 2.7e-12 46.9 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 KEG09655.1 - 5.8e-09 36.0 0.1 1.7e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KEG09655.1 - 7.4e-06 26.6 2.3 0.0015 19.2 0.0 3.8 4 0 0 4 4 4 1 Double-stranded RNA binding motif AAA_22 PF13401.6 KEG09655.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEG09655.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KEG09655.1 - 0.013 15.0 0.3 0.38 10.2 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein OB_NTP_bind PF07717.16 KEG09655.1 - 0.015 15.7 0.4 0.058 13.8 0.0 2.3 3 0 0 3 3 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KEG09655.1 - 0.021 15.1 0.0 0.067 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KEG09655.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KEG09655.1 - 0.059 12.9 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2448 PF10476.9 KEG09656.1 - 0.012 15.5 0.3 0.026 14.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) GET2 PF08690.10 KEG09656.1 - 0.012 15.3 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Tropomyosin PF00261.20 KEG09657.1 - 0.082 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin Coat_F PF07875.12 KEG09657.1 - 0.43 10.8 2.0 0.71 10.1 2.0 1.3 1 0 0 1 1 1 0 Coat F domain Kelch_5 PF13854.6 KEG09658.1 - 1.2e-15 57.0 8.8 9.3e-07 28.7 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KEG09658.1 - 2.2e-13 49.6 2.0 1e-07 31.6 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KEG09658.1 - 3.6e-11 42.9 0.1 0.0001 22.2 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG09658.1 - 1.1e-09 37.7 3.3 2.8e-05 23.6 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 KEG09658.1 - 8.6e-09 35.4 1.2 0.00053 20.2 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KEG09658.1 - 2e-07 31.1 0.2 0.028 14.7 0.0 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain DUF4482 PF14818.6 KEG09659.1 - 0.065 14.1 0.3 0.16 12.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) XRN_N PF03159.18 KEG09662.1 - 0.00065 19.2 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Hrs_helical PF12210.8 KEG09663.1 - 0.038 14.5 3.9 0.16 12.5 2.2 2.0 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Syntaxin-6_N PF09177.11 KEG09663.1 - 0.25 11.9 5.0 0.24 12.0 3.4 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Chorein_N PF12624.7 KEG09664.1 - 0.00038 20.5 0.2 0.0031 17.6 0.0 2.7 2 1 1 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KEG09664.1 - 0.022 14.6 0.1 0.059 13.2 0.1 1.8 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal PMSR PF01625.21 KEG09665.1 - 2.8e-56 189.9 1.1 3.4e-56 189.7 1.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TPR_14 PF13428.6 KEG09665.1 - 0.018 15.8 0.1 1.2 10.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09665.1 - 0.072 13.6 0.1 0.56 10.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09665.1 - 0.072 12.9 2.0 0.36 10.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Nuc_deoxyrib_tr PF05014.15 KEG09665.1 - 0.097 12.7 0.2 0.16 12.0 0.0 1.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase TPR_8 PF13181.6 KEG09665.1 - 0.13 12.6 0.5 2 8.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 KEG09666.1 - 3.2e-05 23.2 0.0 9.5e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KEG09666.1 - 6.4e-05 23.3 0.0 0.00028 21.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG09666.1 - 0.018 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KEG09666.1 - 0.019 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KEG09666.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Integrase_Zn PF02022.19 KEG09666.1 - 0.24 11.4 0.8 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain VWA_2 PF13519.6 KEG09667.1 - 2.6e-08 34.5 0.5 7.7e-08 33.0 0.0 2.0 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 KEG09667.1 - 6.1e-06 25.8 15.1 0.0022 17.8 5.0 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA PF00092.28 KEG09667.1 - 0.0021 18.3 0.1 0.0042 17.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3783 PF12646.7 KEG09667.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) MscS_TM PF12794.7 KEG09667.1 - 6.2 5.6 7.1 2.6 6.8 4.8 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Atg14 PF10186.9 KEG09668.1 - 0.015 14.4 0.4 0.029 13.5 0.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NT5C PF06941.12 KEG09668.1 - 0.13 12.1 0.3 0.36 10.7 0.1 1.8 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) APG6_N PF17675.1 KEG09668.1 - 1.2 9.7 13.1 0.038 14.5 5.3 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Synaphin PF05835.12 KEG09668.1 - 5.5 7.3 10.5 0.73 10.1 0.1 2.5 3 0 0 3 3 3 0 Synaphin protein Carn_acyltransf PF00755.20 KEG09669.1 - 1.9e-79 267.9 0.0 2.6e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Urb2 PF10441.9 KEG09669.1 - 0.1 12.5 2.3 0.11 12.5 0.1 2.0 2 1 0 2 2 2 0 Urb2/Npa2 family Fn3_assoc PF13287.6 KEG09670.1 - 1.4e-19 70.0 0.1 1.1e-08 35.1 0.0 3.4 3 0 0 3 3 3 2 Fn3 associated CHB_HEX_C_1 PF13290.6 KEG09670.1 - 2.1e-18 66.1 0.7 5.5e-09 35.9 0.3 3.4 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.13 KEG09670.1 - 0.0011 18.9 0.0 1.6 8.7 0.0 3.2 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain SBP_bac_5 PF00496.22 KEG09670.1 - 0.014 14.3 0.2 0.025 13.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Macoilin PF09726.9 KEG09670.1 - 5.5 5.4 8.3 7.9 4.9 8.3 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 KEG09671.1 - 1.7 9.2 10.9 0.68 10.5 6.3 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region TPM_phosphatase PF04536.14 KEG09672.1 - 5e-15 55.8 0.0 7.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 TPM domain Cytochrome_C7 PF14522.6 KEG09672.1 - 1.3 9.1 9.5 2.3 8.3 5.7 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c FYVE_2 PF02318.16 KEG09672.1 - 1.7 8.9 8.0 6.9 6.9 8.0 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger WD40 PF00400.32 KEG09673.1 - 1e-19 70.5 4.9 0.00022 21.9 0.0 6.5 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG09673.1 - 1e-09 38.6 0.0 0.0049 17.1 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Not3 PF04065.15 KEG09674.1 - 6.6e-57 192.6 12.7 1e-56 192.0 12.7 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Dicty_REP PF05086.12 KEG09674.1 - 0.017 13.1 8.5 0.29 9.1 1.8 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 KEG09674.1 - 0.69 9.9 31.1 2.4 8.2 18.6 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein SLBP_RNA_bind PF15247.6 KEG09675.1 - 1.7e-24 85.7 2.9 1.7e-24 85.7 2.9 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain CDC45 PF02724.14 KEG09676.1 - 0.0086 14.4 6.7 0.009 14.4 6.7 1.0 1 0 0 1 1 1 1 CDC45-like protein VIR_N PF15912.5 KEG09676.1 - 1.1 8.8 12.0 1.3 8.6 12.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Rad51 PF08423.11 KEG09677.1 - 5.9e-07 29.0 0.0 2.7e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 KEG09677.1 - 5.2e-06 26.1 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KEG09677.1 - 0.00028 20.5 0.2 0.031 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KEG09677.1 - 0.006 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KEG09677.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KEG09677.1 - 0.14 12.4 0.0 0.64 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain PIG-F PF06699.11 KEG09678.1 - 0.0013 18.9 2.6 0.0017 18.6 2.6 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F LPG_synthase_TM PF03706.13 KEG09678.1 - 0.021 14.4 8.8 0.041 13.4 8.8 1.4 1 1 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Complex1_LYR PF05347.15 KEG09679.1 - 9.3e-08 32.0 1.0 1.4e-07 31.4 1.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UPF0113 PF03657.13 KEG09680.1 - 5.4e-18 65.0 0.0 1.3e-17 63.8 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 KEG09680.1 - 3.7e-16 59.4 0.0 5.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain DUF5317 PF17248.2 KEG09680.1 - 0.0066 16.5 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5317) Ribosomal_L18 PF17135.4 KEG09680.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e SNARE PF05739.19 KEG09681.1 - 7.6e-08 32.2 0.4 2.2e-07 30.7 0.4 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KEG09681.1 - 0.052 13.9 8.0 5 7.6 0.1 2.7 2 0 0 2 2 2 0 Syntaxin-like protein Rit1_C PF17184.4 KEG09681.1 - 0.24 10.8 2.2 0.42 10.0 1.7 1.7 1 1 1 2 2 2 0 Rit1 N-terminal domain AAA_26 PF13500.6 KEG09681.1 - 1.4 8.7 4.3 1 9.1 0.8 2.0 2 0 0 2 2 2 0 AAA domain PI3_PI4_kinase PF00454.27 KEG09683.1 - 0.23 11.2 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DZR PF12773.7 KEG09685.1 - 0.0062 16.5 1.7 0.027 14.5 1.7 2.1 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 KEG09685.1 - 0.053 13.7 0.7 12 6.1 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Guanylate_cyc PF00211.20 KEG09687.1 - 2.2e-11 43.7 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Oxidored_q6 PF01058.22 KEG09688.1 - 5.1e-19 68.4 0.1 6.8e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NAD_binding_1 PF00175.21 KEG09689.1 - 2.4e-22 79.7 0.0 5e-22 78.6 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG09689.1 - 4.6e-15 55.8 0.0 7.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEG09689.1 - 1.1e-06 28.8 0.0 5e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain UBA PF00627.31 KEG09690.1 - 6.9e-09 35.4 0.1 6.9e-09 35.4 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 KEG09690.1 - 0.00048 19.8 0.0 0.00099 18.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family HOIP-UBA PF16678.5 KEG09690.1 - 0.0049 16.9 0.2 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 HOIP UBA domain pair Atg8 PF02991.16 KEG09696.1 - 2.3e-15 56.7 0.0 3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEG09696.1 - 0.16 12.4 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Hexapep PF00132.24 KEG09697.1 - 0.00014 21.5 1.4 0.098 12.4 0.2 4.0 2 1 3 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEG09697.1 - 0.0045 16.7 0.3 0.18 11.6 0.0 2.8 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase PDZ_2 PF13180.6 KEG09700.1 - 9.3e-09 35.5 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KEG09700.1 - 1.4e-06 28.0 0.0 7.2e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KEG09700.1 - 4.5e-05 23.7 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PI-PLC-X PF00388.19 KEG09700.1 - 0.0027 17.3 0.0 0.0076 15.8 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 KEG09700.1 - 0.035 14.6 0.0 0.096 13.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Ribosomal_S30 PF04758.14 KEG09701.1 - 1.4e-25 89.2 10.6 1.6e-25 89.0 10.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.16 KEG09703.1 - 5.8e-18 65.7 0.5 8.3e-18 65.2 0.5 1.3 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 KEG09703.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 PIH1 CS-like domain TPR_2 PF07719.17 KEG09707.1 - 3.2e-23 79.9 20.1 6.3e-06 25.9 0.1 8.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09707.1 - 4.7e-19 67.3 12.3 1.3e-05 24.8 0.2 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEG09707.1 - 2.7e-15 55.2 11.4 0.084 13.1 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09707.1 - 5.9e-14 52.1 19.5 0.019 15.2 0.4 7.8 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEG09707.1 - 5.6e-13 47.9 13.1 0.0019 18.1 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09707.1 - 4.6e-12 46.3 10.7 0.0014 19.0 0.0 7.1 5 2 2 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG09707.1 - 5.8e-11 42.9 14.9 0.019 15.6 0.1 5.9 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09707.1 - 1.3e-09 37.5 5.5 0.073 12.8 0.0 5.4 4 2 2 6 6 6 3 TPR repeat TPR_14 PF13428.6 KEG09707.1 - 1.7e-08 34.6 14.1 1.1 10.3 0.0 7.8 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG09707.1 - 2e-08 34.1 6.6 1.1 9.8 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG09707.1 - 3.3e-08 33.6 23.7 6.8e-05 23.0 0.3 5.0 3 3 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KEG09707.1 - 2.8e-05 23.5 4.4 0.77 8.9 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEG09707.1 - 0.00098 18.9 8.9 1.6 8.7 0.1 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG09707.1 - 0.00099 19.6 14.7 2.9 8.7 0.1 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KEG09707.1 - 0.0022 17.6 0.3 0.95 9.1 0.2 2.7 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 KEG09707.1 - 0.0037 17.4 5.0 7.6 6.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG09707.1 - 0.023 14.7 4.1 17 5.6 0.1 5.3 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KEG09707.1 - 0.064 13.3 1.7 0.14 12.2 0.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) DUF4919 PF16266.5 KEG09707.1 - 0.08 12.9 0.3 14 5.6 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) DUF3128 PF11326.8 KEG09707.1 - 0.089 13.2 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) IKI3 PF04762.12 KEG09707.1 - 0.1 10.6 0.6 0.14 10.1 0.6 1.1 1 0 0 1 1 1 0 IKI3 family UPF0061 PF02696.14 KEG09707.1 - 0.13 11.0 0.3 0.22 10.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF572 PF04502.13 KEG09708.1 - 0.8 9.3 7.1 1.1 8.8 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FHIPEP PF00771.20 KEG09708.1 - 0.84 8.0 5.4 0.18 10.2 1.8 1.6 1 1 1 2 2 2 0 FHIPEP family ASF1_hist_chap PF04729.13 KEG09709.1 - 2e-45 154.5 0.0 2.4e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone BRCA-2_OB1 PF09103.10 KEG09710.1 - 1.3e-22 80.0 0.0 2.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 KEG09710.1 - 0.0021 17.7 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 BRCA2 repeat DUF5521 PF17659.1 KEG09710.1 - 0.053 11.4 0.1 0.075 10.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MRG PF05712.13 KEG09711.1 - 0.0077 15.6 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 MRG Sec34 PF04136.15 KEG09712.1 - 0.021 14.7 2.4 0.021 14.7 2.4 1.8 2 0 0 2 2 2 0 Sec34-like family FapA PF03961.13 KEG09712.1 - 0.12 11.0 1.0 0.16 10.6 1.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ApoLp-III PF07464.11 KEG09712.1 - 0.13 12.4 6.1 0.3 11.2 5.9 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) zf-C4H2 PF10146.9 KEG09712.1 - 0.15 12.3 6.6 0.29 11.4 6.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein AAA_13 PF13166.6 KEG09712.1 - 0.18 10.4 6.8 0.21 10.2 6.8 1.1 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.9 KEG09712.1 - 0.51 9.2 10.5 0.77 8.7 9.3 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 KEG09712.1 - 0.68 9.0 9.2 0.86 8.6 9.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KEG09712.1 - 0.69 9.2 7.3 0.19 11.0 4.0 1.7 1 1 1 2 2 2 0 FAM76 protein FAA_hydro_N_2 PF18288.1 KEG09712.1 - 0.82 10.1 11.6 1.3 9.5 0.2 3.5 1 1 2 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Spc7 PF08317.11 KEG09712.1 - 0.92 8.3 18.8 1.1 8.0 15.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein eIF3_N PF09440.10 KEG09712.1 - 0.98 9.9 5.9 11 6.4 0.2 2.4 1 1 2 3 3 3 0 eIF3 subunit 6 N terminal domain V_ATPase_I PF01496.19 KEG09712.1 - 1.1 7.0 4.3 1.1 7.0 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 KEG09712.1 - 1.2 9.6 16.7 0.64 10.4 13.9 1.8 1 1 1 2 2 2 0 Fez1 UPF0242 PF06785.11 KEG09712.1 - 1.7 8.8 12.5 0.51 10.4 8.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 KEG09712.1 - 3.2 8.4 8.4 12 6.5 7.4 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Nup54 PF13874.6 KEG09712.1 - 4.6 7.4 22.1 7.6 6.6 15.1 3.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Exonuc_VII_L PF02601.15 KEG09712.1 - 5.4 6.5 14.6 11 5.5 14.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit NYD-SP28_assoc PF14775.6 KEG09712.1 - 8.4 6.6 11.1 0.5 10.5 1.2 3.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain MID_MedPIWI PF18296.1 KEG09713.1 - 0.16 11.8 4.7 0.19 11.5 0.6 2.3 2 0 0 2 2 2 0 MID domain of medPIWI PGK PF00162.19 KEG09716.1 - 6.3e-165 548.7 0.2 5.2e-158 525.9 0.0 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase WD40 PF00400.32 KEG09722.1 - 1.2e-10 41.7 9.1 1 10.3 0.1 8.0 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG09722.1 - 0.00073 19.8 0.0 2.4 8.5 0.0 4.8 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PKcGMP_CC PF16808.5 KEG09722.1 - 0.015 15.1 1.2 0.015 15.1 1.2 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GLE1 PF07817.13 KEG09722.1 - 2.4 7.3 6.0 0.61 9.3 1.7 2.0 2 0 0 2 2 2 0 GLE1-like protein DNA_pol_B PF00136.21 KEG09723.1 - 1.1e-127 426.6 0.0 1.8e-127 425.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEG09723.1 - 4.1e-42 144.5 0.0 7.2e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 KEG09723.1 - 0.0016 18.2 1.3 0.066 13.0 1.1 2.5 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 KEG09723.1 - 0.009 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral ERO1 PF04137.15 KEG09724.1 - 1.8e-88 297.1 0.0 2.3e-88 296.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pox_E10 PF04805.12 KEG09724.1 - 0.1 12.5 0.2 0.29 11.0 0.2 1.7 1 0 0 1 1 1 0 E10-like protein conserved region CDP-OH_P_transf PF01066.21 KEG09725.1 - 2.1e-17 63.7 0.2 2.1e-17 63.7 0.2 3.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gtr1_RagA PF04670.12 KEG09727.1 - 1.7e-64 217.4 0.0 2.1e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG09727.1 - 4e-06 26.9 0.0 1e-05 25.6 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KEG09727.1 - 0.00022 20.7 0.0 0.00067 19.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG09727.1 - 0.0044 17.2 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KEG09727.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B APH PF01636.23 KEG09731.1 - 1.3e-13 51.4 0.0 3.8e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family MORN PF02493.20 KEG09732.1 - 2.2e-06 27.2 1.5 0.0099 15.7 0.0 4.6 5 0 0 5 5 5 2 MORN repeat MFS_1 PF07690.16 KEG09735.1 - 1e-19 70.7 27.3 2.8e-14 52.8 19.7 3.2 1 1 0 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG09735.1 - 7.9e-08 32.1 19.9 6.6e-07 29.1 19.8 2.4 1 1 0 1 1 1 1 Nodulin-like PP2C PF00481.21 KEG09737.1 - 1.9e-30 106.4 0.0 4.1e-27 95.4 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP_var PF17807.1 KEG09737.1 - 2.6 7.9 6.4 7.2 6.4 6.4 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger Pkinase PF00069.25 KEG09738.1 - 4.4e-69 232.8 0.0 5.6e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09738.1 - 3.4e-35 121.6 0.0 5.1e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG09738.1 - 4.9e-11 43.1 0.0 3e-09 37.3 0.0 2.5 1 1 0 1 1 1 1 PH domain FYVE PF01363.21 KEG09738.1 - 6.7e-11 42.2 11.7 6.7e-11 42.2 11.7 2.4 2 0 0 2 2 2 1 FYVE zinc finger Kinase-like PF14531.6 KEG09738.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG09738.1 - 0.0025 16.7 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG09738.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KEG09738.1 - 0.01 16.1 4.6 0.01 16.1 4.6 2.3 2 0 0 2 2 2 0 C1 domain ADK_lid PF05191.14 KEG09738.1 - 0.2 11.7 6.5 0.1 12.6 2.0 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 KEG09738.1 - 3.5 7.2 15.1 3.4 7.2 5.5 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Cript PF10235.9 KEG09738.1 - 4.9 7.8 8.9 1.5 9.4 5.0 2.2 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT FHA PF00498.26 KEG09751.1 - 1e-14 54.6 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEG09751.1 - 4.7e-05 23.6 0.1 0.34 11.3 0.0 2.5 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain GPHH PF16905.5 KEG09752.1 - 0.17 11.7 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated PRIMA1 PF16101.5 KEG09754.1 - 0.0017 18.4 2.6 0.91 9.6 0.1 2.6 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 ADK PF00406.22 KEG09755.1 - 9.8e-25 87.4 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KEG09755.1 - 7.1e-14 51.5 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KEG09755.1 - 1.4e-10 41.7 0.0 2.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG09755.1 - 4.9e-07 30.3 0.0 9.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG09755.1 - 0.0002 21.5 0.0 0.00045 20.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEG09755.1 - 0.00022 21.3 0.0 0.00067 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 KEG09755.1 - 0.0012 19.2 0.0 0.027 14.8 0.0 2.2 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 KEG09755.1 - 0.0034 17.8 0.0 0.0038 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KEG09755.1 - 0.0035 17.1 0.0 0.0088 15.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KEG09755.1 - 0.011 16.1 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEG09755.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEG09755.1 - 0.025 15.0 0.0 0.038 14.4 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KEG09755.1 - 0.094 12.4 0.0 2.6 7.7 0.0 2.4 3 0 0 3 3 3 0 Thymidylate kinase AAA_25 PF13481.6 KEG09755.1 - 0.11 12.1 0.5 12 5.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KEG09755.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KEG09755.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ldh_1_C PF02866.18 KEG09756.1 - 1.4e-17 64.1 0.0 3.2e-16 59.7 0.0 2.2 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEG09756.1 - 3.9e-14 52.9 0.0 6.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEG09757.1 - 7.2e-46 156.2 0.0 1.1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEG09757.1 - 4.1e-45 153.4 0.0 5.7e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEG09757.1 - 0.0079 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KEG09757.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Lycopene_cycl PF05834.12 KEG09758.1 - 0.083 11.9 0.2 0.093 11.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_38N PF01074.22 KEG09759.1 - 1.9e-70 237.5 3.8 2.7e-70 237.0 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KEG09759.1 - 3.1e-25 89.5 0.0 4.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KEG09759.1 - 1.5e-18 66.8 0.0 3.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KEG09759.1 - 2e-06 27.8 0.1 5.2e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Nop25 PF09805.9 KEG09760.1 - 7.8e-11 42.6 11.7 7.8e-11 42.6 11.7 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Methyltransf_25 PF13649.6 KEG09761.1 - 9.1e-05 23.1 0.0 0.00025 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG09761.1 - 0.00057 19.7 0.0 0.0034 17.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG09761.1 - 0.0022 18.6 0.0 0.0071 17.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG09761.1 - 0.0073 17.0 0.0 0.064 14.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG09761.1 - 0.0074 16.1 0.0 0.07 13.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 KEG09761.1 - 0.0079 15.8 0.0 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KEG09761.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KEG09761.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KEG09761.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KEG09761.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF72 PF01904.18 KEG09763.1 - 2.5e-38 132.4 0.0 9e-34 117.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF72 DUF4926 PF16277.5 KEG09763.1 - 0.13 11.7 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) EDR1 PF14381.6 KEG09764.1 - 8.3e-26 90.9 0.0 1.4e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Pkinase PF00069.25 KEG09764.1 - 8.7e-26 90.8 0.0 1.4e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09764.1 - 8.5e-18 64.6 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG09764.1 - 0.00049 19.0 0.0 0.0043 15.9 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase CENP-B_dimeris PF09026.10 KEG09764.1 - 0.3 11.5 6.5 1.1 9.7 6.5 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIE-A_C PF11521.8 KEG09764.1 - 0.79 10.1 3.9 0.35 11.2 0.4 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-PARP PF00645.18 KEG09765.1 - 6.1e-18 65.5 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 KEG09765.1 - 2e-10 40.5 0.4 3.6e-10 39.6 0.4 1.4 1 0 0 1 1 1 1 PBZ domain Metallophos PF00149.28 KEG09766.1 - 5.9e-21 75.9 0.0 1.6e-19 71.3 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ALG3 PF05208.13 KEG09767.1 - 3.9e-128 427.9 13.2 4.5e-128 427.7 13.2 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4381 PF14316.6 KEG09767.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) WD40 PF00400.32 KEG09768.1 - 8.6e-10 39.1 8.4 0.18 12.7 1.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Spt20 PF12090.8 KEG09769.1 - 6 6.4 9.7 14 5.2 9.7 1.5 1 1 0 1 1 1 0 Spt20 family PI3_PI4_kinase PF00454.27 KEG09771.1 - 4e-34 118.5 0.1 3e-22 79.6 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KEG09771.1 - 1.4e-10 40.9 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FWWh PF14922.6 KEG09772.1 - 1.1e-06 28.7 0.0 0.00093 19.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function Ras PF00071.22 KEG09774.1 - 1.2e-27 96.5 0.0 5.8e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEG09774.1 - 5.2e-21 75.1 0.0 1.6e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG09774.1 - 6.5e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG09774.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG09774.1 - 0.0081 16.5 0.1 0.022 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEG09774.1 - 0.013 15.4 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DLIC PF05783.11 KEG09774.1 - 0.044 12.6 0.0 0.32 9.8 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KEG09774.1 - 0.045 12.9 0.1 0.83 8.7 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 KEG09774.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 KEG09774.1 - 0.16 11.4 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TROVE PF05731.11 KEG09779.1 - 3.5e-67 227.4 0.1 9.4e-43 146.9 0.2 2.4 1 1 1 2 2 2 2 TROVE domain WD40 PF00400.32 KEG09779.1 - 2.1e-18 66.3 16.5 0.082 13.8 0.0 10.2 10 0 0 10 10 10 6 WD domain, G-beta repeat DUF4062 PF13271.6 KEG09779.1 - 1.2e-13 51.3 0.0 3.9e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) ANAPC4_WD40 PF12894.7 KEG09779.1 - 2.9e-06 27.5 0.0 3.7 7.9 0.0 5.5 6 2 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEG09779.1 - 1.3e-05 25.2 0.0 3.3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEG09779.1 - 0.00053 20.4 0.1 0.0021 18.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Mito_fiss_reg PF05308.11 KEG09779.1 - 0.12 12.5 2.1 0.36 10.9 2.1 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator Adap_comp_sub PF00928.21 KEG09780.1 - 4.1e-67 226.3 0.0 5.1e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEG09780.1 - 0.015 15.2 0.3 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Clathrin adaptor complex small chain ACBP PF00887.19 KEG09781.1 - 1.5e-17 63.6 0.7 1.6e-17 63.5 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP49 PF06068.13 KEG09782.1 - 3.1e-158 526.6 3.7 3.1e-158 526.5 1.2 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 KEG09782.1 - 9.4e-24 83.3 1.2 2.9e-23 81.8 1.2 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KEG09782.1 - 5.3e-08 33.3 3.0 7.3e-05 23.2 0.1 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEG09782.1 - 2.9e-06 27.1 0.1 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG09782.1 - 1.1e-05 25.8 0.2 0.18 12.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KEG09782.1 - 1.9e-05 25.1 0.8 0.00063 20.2 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 KEG09782.1 - 2.3e-05 23.9 0.2 5.2e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 KEG09782.1 - 3e-05 24.0 0.8 0.0038 17.2 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KEG09782.1 - 4.9e-05 23.7 3.5 0.00038 20.8 1.6 2.6 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KEG09782.1 - 0.00017 21.1 1.1 0.0024 17.3 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KEG09782.1 - 0.011 15.0 0.3 0.027 13.7 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 KEG09782.1 - 0.013 15.9 1.6 0.074 13.5 0.1 2.7 3 1 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 KEG09782.1 - 0.026 14.2 0.0 8.2 6.1 0.1 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KEG09782.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KEG09782.1 - 0.037 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KEG09782.1 - 0.037 14.3 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEG09782.1 - 0.039 13.5 0.2 0.11 12.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEG09782.1 - 0.059 13.5 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEG09782.1 - 0.068 12.7 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region GATase PF00117.28 KEG09782.1 - 0.072 12.9 0.6 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase class-I AAA_30 PF13604.6 KEG09782.1 - 0.079 12.7 3.8 0.9 9.2 0.1 3.1 4 0 0 4 4 4 0 AAA domain CPT PF07931.12 KEG09782.1 - 0.098 12.5 0.3 0.52 10.1 0.0 2.3 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 KEG09782.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KEG09782.1 - 0.21 11.4 0.2 1.6 8.5 0.1 2.4 3 0 0 3 3 2 0 P-loop containing region of AAA domain SUV3_C PF12513.8 KEG09783.1 - 2.3e-11 43.5 0.6 5.8e-11 42.2 0.6 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KEG09783.1 - 9.4e-10 38.2 0.1 2.3e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KEG09783.1 - 1.1e-06 28.9 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG09783.1 - 0.085 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoLip_ATPase_C PF16212.5 KEG09784.1 - 2.8e-46 158.3 23.5 2.8e-46 158.3 23.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEG09784.1 - 7.6e-24 83.2 0.2 2e-23 81.8 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEG09784.1 - 2.2e-10 41.2 2.5 7.1e-05 23.2 1.5 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEG09784.1 - 4.1e-09 36.4 0.0 1.5e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KEG09784.1 - 6.7e-05 22.5 0.0 0.00067 19.2 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEG09784.1 - 0.015 15.1 0.1 0.034 13.9 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 KEG09784.1 - 0.13 11.7 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DNA_topoisoIV PF00521.20 KEG09786.1 - 3.1e-95 319.6 0.0 5.3e-95 318.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KEG09786.1 - 5.2e-34 117.3 0.7 9.6e-34 116.4 0.7 1.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KEG09786.1 - 2.8e-08 33.5 0.0 5.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KEG09786.1 - 2.9e-07 31.0 0.0 6.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KEG09786.1 - 4.2e-07 30.1 0.0 1.4e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KEG09786.1 - 0.00095 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UCH PF00443.29 KEG09787.1 - 2.3e-35 122.3 0.0 3.2e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG09787.1 - 5.4e-11 42.6 0.0 1.5e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KEG09787.1 - 8.8e-05 21.9 0.0 0.19 11.0 0.0 2.8 3 0 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 CorA PF01544.18 KEG09788.1 - 6.6e-27 94.6 0.6 1.4e-22 80.4 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SHOCT PF09851.9 KEG09789.1 - 1.1e-05 25.0 0.2 1.6e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Short C-terminal domain Actin PF00022.19 KEG09790.1 - 4.3e-88 295.7 0.0 1.8e-87 293.6 0.0 1.7 1 1 0 1 1 1 1 Actin baeRF_family10 PF18854.1 KEG09790.1 - 0.025 14.8 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 DAG1 PF05454.11 KEG09791.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4483 PF14825.6 KEG09792.1 - 0.24 11.1 0.3 24 4.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4483) Piezo_RRas_bdg PF12166.8 KEG09793.1 - 4.5e-93 312.8 0.0 6.9e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain CAP_N PF01213.19 KEG09793.1 - 0.16 11.4 6.9 0.47 9.9 6.9 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IMS PF00817.20 KEG09797.1 - 5.7e-37 127.0 0.2 2.2e-36 125.1 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KEG09797.1 - 1.5e-08 35.3 2.1 4.3e-08 33.9 2.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KEG09797.1 - 1.1e-05 25.4 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif ANTH PF07651.16 KEG09797.1 - 0.025 13.6 0.5 0.047 12.7 0.5 1.3 1 0 0 1 1 1 0 ANTH domain IMS PF00817.20 KEG09798.1 - 4.3e-07 30.0 0.0 8.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 KEG09798.1 - 0.0091 16.3 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif RepB_primase PF16793.5 KEG09799.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid sCache_3_2 PF17203.4 KEG09799.1 - 0.19 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Single cache domain 3 Peptidase_M8 PF01457.16 KEG09800.1 - 4.7e-143 477.7 0.0 6.6e-143 477.2 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Erythrovirus_X PF06795.11 KEG09801.1 - 0.017 15.4 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Erythrovirus X protein DUF4611 PF15387.6 KEG09802.1 - 0.21 11.8 9.9 0.4 10.9 2.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TFIIA PF03153.13 KEG09802.1 - 2.8 7.9 8.2 5.4 6.9 8.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 KEG09803.1 - 1.2e-11 44.8 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ank_4 PF13637.6 KEG09803.1 - 4.4e-11 43.1 0.2 0.00038 20.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG09803.1 - 1.1e-10 42.0 0.0 2.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG09803.1 - 1.1e-09 38.4 0.1 0.00032 20.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEG09803.1 - 1.4e-08 34.8 0.7 0.0093 16.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KEG09803.1 - 5.7e-06 26.3 0.0 0.14 12.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat RAP1 PF07218.11 KEG09803.1 - 6.3 5.0 5.0 8.5 4.5 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YEATS PF03366.16 KEG09804.1 - 1e-16 60.7 0.1 2e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 YEATS family PALP PF00291.25 KEG09805.1 - 3.8e-45 154.5 0.4 4.3e-45 154.4 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mito_carr PF00153.27 KEG09808.1 - 8.1e-37 125.0 1.8 1.5e-15 56.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec20 PF03908.13 KEG09809.1 - 7.1e-05 22.7 2.4 0.00033 20.5 0.3 2.1 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.8 KEG09809.1 - 0.034 14.4 1.8 0.046 14.0 1.4 1.4 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Glyco_hydro_36 PF17167.4 KEG09809.1 - 0.054 12.2 0.2 0.12 11.0 0.2 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain V-ATPase_G_2 PF16999.5 KEG09810.1 - 0.025 15.0 4.0 0.033 14.6 4.0 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CinA_KH PF18146.1 KEG09810.1 - 0.98 9.6 5.5 1.1 9.5 0.6 2.2 1 1 1 2 2 2 0 Damage-inducible protein CinA KH domain DUF2627 PF11118.8 KEG09811.1 - 0.063 13.9 0.1 0.89 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) HSP33 PF01430.19 KEG09812.1 - 6.2e-13 48.8 4.7 4e-11 42.9 4.7 2.9 1 1 0 1 1 1 1 Hsp33 protein Arm PF00514.23 KEG09813.1 - 8.9e-61 200.2 18.8 3.2e-09 36.5 0.0 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEG09813.1 - 4.7e-23 81.3 6.9 1.7e-06 28.4 0.1 6.7 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KEG09813.1 - 6.6e-12 45.7 0.3 0.033 14.6 0.0 5.0 1 1 6 7 7 7 6 HEAT repeats Arm_3 PF16186.5 KEG09813.1 - 2.6e-11 42.9 0.0 7.3e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 KEG09813.1 - 3.5e-10 39.2 0.3 1.1 9.6 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat NopRA1 PF16201.5 KEG09813.1 - 0.026 14.1 0.0 0.59 9.7 0.0 3.2 4 1 1 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 KEG09813.1 - 0.12 12.4 0.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain MA3 PF02847.17 KEG09814.1 - 1.6e-09 37.7 0.1 3.8e-09 36.5 0.1 1.7 2 0 0 2 2 2 1 MA3 domain SR-25 PF10500.9 KEG09814.1 - 0.15 11.6 23.7 0.41 10.2 0.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_phi PF04931.13 KEG09814.1 - 6.9 4.6 10.1 18 3.3 10.1 1.6 1 0 0 1 1 1 0 DNA polymerase phi DHHC PF01529.20 KEG09816.1 - 3.4e-32 111.3 13.0 3.4e-32 111.3 13.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase NUDIX PF00293.28 KEG09817.1 - 4.4e-14 52.6 0.0 6.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF676 PF05057.14 KEG09819.1 - 0.065 12.7 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) SET PF00856.28 KEG09820.1 - 4.9e-11 43.3 0.0 1.3e-10 41.9 0.0 1.7 1 1 0 1 1 1 1 SET domain RLAN PF14401.6 KEG09820.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain EccE PF11203.8 KEG09820.1 - 0.12 12.7 0.9 7 7.0 0.0 3.3 1 1 2 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Na_H_Exchanger PF00999.21 KEG09821.1 - 7e-45 153.4 45.0 1.1e-44 152.8 45.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_19 PF14559.6 KEG09822.1 - 0.00015 22.2 5.1 0.0054 17.2 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG09822.1 - 0.00024 21.3 0.8 1.6 9.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG09822.1 - 0.0027 17.8 3.7 0.43 10.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09822.1 - 0.0063 16.3 2.0 1.7 8.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG09822.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KEG09822.1 - 0.11 12.7 0.2 4.4 7.6 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KEG09822.1 - 0.21 11.8 4.2 18 5.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG09822.1 - 0.48 11.4 5.3 1e+02 4.1 0.0 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_28 PF02636.17 KEG09823.1 - 3.8e-60 203.7 0.1 5.4e-60 203.2 0.1 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DnaI_N PF07319.11 KEG09823.1 - 0.039 14.6 0.2 1.8 9.3 0.1 2.5 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus MadM PF03818.13 KEG09824.1 - 1.7 8.6 6.6 1.7 8.6 0.4 3.2 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit tRNA_edit PF04073.15 KEG09826.1 - 2.4e-08 34.1 0.1 9.6e-08 32.1 0.0 2.0 2 1 0 2 2 2 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.20 KEG09827.1 - 3.8e-69 233.2 0.0 5.4e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEG09827.1 - 4.9e-09 36.0 0.0 9.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEG09827.1 - 4e-05 23.2 0.1 0.02 14.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Erythro_esteras PF05139.14 KEG09827.1 - 0.0017 18.3 0.0 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 Erythromycin esterase MutS_V PF00488.21 KEG09828.1 - 1.2e-39 136.3 0.0 3.9e-39 134.6 0.0 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEG09828.1 - 1e-20 74.8 1.8 3.6e-20 73.0 1.8 1.8 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KEG09828.1 - 1.6e-07 31.7 0.0 5.8e-07 29.9 0.0 2.0 2 0 0 2 2 1 1 MutS domain II MutS_IV PF05190.18 KEG09828.1 - 0.0012 19.1 0.0 0.0045 17.3 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_22 PF13401.6 KEG09828.1 - 0.002 18.4 0.1 0.032 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG09828.1 - 0.003 17.9 0.0 0.014 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KEG09828.1 - 0.0034 17.9 0.1 0.0089 16.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KEG09828.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 KEG09828.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEG09828.1 - 0.031 14.0 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEG09828.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KdpD PF02702.17 KEG09828.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain S36_mt PF10937.8 KEG09828.1 - 0.077 14.6 0.2 0.38 12.4 0.2 2.2 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial AAA_27 PF13514.6 KEG09828.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEG09828.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CDC45 PF02724.14 KEG09828.1 - 5.7 5.1 8.7 9.5 4.4 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4499 PF14934.6 KEG09829.1 - 0.00028 21.2 0.6 0.00028 21.2 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) zf-Dof PF02701.15 KEG09830.1 - 0.059 13.5 0.3 0.09 12.9 0.3 1.3 1 0 0 1 1 1 0 Dof domain, zinc finger ABC2_membrane PF01061.24 KEG09831.1 - 5.4e-10 39.0 24.4 8.4e-10 38.4 24.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KEG09831.1 - 5.7e-07 30.1 0.0 9.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 KEG09831.1 - 1 9.3 4.4 3.8 7.5 0.0 3.5 4 0 0 4 4 4 0 CDR ABC transporter zf-C2HC_2 PF13913.6 KEG09832.1 - 1.1e-11 44.3 27.2 1.7e-08 34.2 2.3 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KEG09832.1 - 0.024 15.1 8.2 8.5 7.1 0.4 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Lar_restr_allev PF14354.6 KEG09832.1 - 0.048 14.0 2.0 0.69 10.3 0.5 3.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_9 PF14369.6 KEG09832.1 - 0.062 13.6 4.6 2.6 8.4 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon YacG PF03884.14 KEG09832.1 - 0.13 12.0 9.9 0.063 13.0 4.5 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-C2H2_4 PF13894.6 KEG09832.1 - 0.74 10.8 12.2 2.2 9.4 1.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Cys_rich_CPXG PF14255.6 KEG09832.1 - 1 9.3 4.1 12 5.9 0.3 2.8 2 0 0 2 2 2 0 Cysteine-rich CPXCG Rad50_zn_hook PF04423.14 KEG09832.1 - 1.4 8.8 6.9 0.44 10.4 0.6 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.6 KEG09832.1 - 4.2 6.9 7.0 20 4.7 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEG09832.1 - 6 7.1 13.3 0.64 10.2 0.2 3.3 3 0 0 3 3 2 0 Zinc ribbon domain FYDLN_acid PF09538.10 KEG09832.1 - 6.2 7.6 11.6 1.1 10.0 0.2 3.9 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF2256 PF10013.9 KEG09832.1 - 7.1 6.8 13.7 0.16 12.1 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) MatE PF01554.18 KEG09833.1 - 5.6e-31 107.4 32.3 7.9e-18 64.6 9.0 2.7 3 0 0 3 3 3 2 MatE FAM176 PF14851.6 KEG09833.1 - 3.1e-06 26.9 1.3 2.2e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 FAM176 family DDDD PF10161.9 KEG09833.1 - 0.039 13.7 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Myc_N PF01056.18 KEG09833.1 - 0.091 12.6 7.4 0.16 11.8 3.8 2.2 2 0 0 2 2 2 0 Myc amino-terminal region MCU PF04678.13 KEG09835.1 - 8.1e-41 140.0 0.0 1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Pkinase PF00069.25 KEG09836.1 - 4.9e-06 26.1 0.0 7.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KEG09836.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Dabb PF07876.12 KEG09837.1 - 1.3e-10 41.8 0.1 1.6e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain nsp8 PF08717.10 KEG09837.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 nsp8 replicase YtpI PF14007.6 KEG09837.1 - 0.086 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 YtpI-like protein Dabb PF07876.12 KEG09838.1 - 2.1e-10 41.1 0.0 2.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HTH_5 PF01022.20 KEG09838.1 - 0.13 12.2 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family UCH PF00443.29 KEG09839.1 - 4.1e-47 160.8 0.0 7.3e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG09839.1 - 4.1e-12 46.3 0.3 3.7e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RXT2_N PF08595.11 KEG09839.1 - 1.2 9.1 6.5 5.5 7.0 0.2 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3246 PF11596.8 KEG09839.1 - 7 6.0 7.8 8.7 5.7 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SNF2_N PF00176.23 KEG09841.1 - 2.8e-30 105.2 0.0 4.6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG09841.1 - 1.2e-10 41.7 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG09841.1 - 6.7e-06 26.2 0.0 4.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PikAIV_N PF18605.1 KEG09841.1 - 0.12 11.9 0.7 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NopRA1 PF16201.5 KEG09842.1 - 3.2e-30 105.2 0.1 1e-29 103.5 0.1 2.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 KEG09842.1 - 7e-06 25.6 0.1 2.3e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Spt20 PF12090.8 KEG09842.1 - 3.1 7.4 12.5 0.14 11.8 3.1 2.5 3 0 0 3 3 3 0 Spt20 family Med3 PF11593.8 KEG09842.1 - 7.1 5.7 9.9 0.38 9.9 2.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 KEG09843.1 - 2.5e-60 204.1 0.0 3.7e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG09843.1 - 8.5e-28 97.3 0.0 1.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KEG09843.1 - 6.2e-11 42.6 3.5 6.7e-05 23.3 1.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG09843.1 - 3.9e-07 29.5 3.6 0.01 15.7 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain Kinase-like PF14531.6 KEG09843.1 - 4.3e-06 26.2 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like EF-hand_1 PF00036.32 KEG09843.1 - 2.2e-05 23.7 0.9 1.3 8.8 0.0 4.6 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 KEG09843.1 - 0.0013 18.6 2.6 0.53 10.2 0.6 3.5 2 2 1 3 3 3 2 EF-hand domain pair Kdo PF06293.14 KEG09843.1 - 0.0067 15.8 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 KEG09843.1 - 0.025 14.9 0.2 0.37 11.2 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain FTA2 PF13095.6 KEG09843.1 - 0.16 11.6 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KEG09843.1 - 0.17 10.8 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Noelin-1 PF12308.8 KEG09845.1 - 0.036 14.0 0.1 0.036 14.0 0.1 2.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein SUIM_assoc PF16619.5 KEG09845.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_S3Ae PF01015.18 KEG09847.1 - 3.9e-70 235.6 6.4 4.6e-70 235.3 6.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Salp15 PF12115.8 KEG09847.1 - 0.15 12.5 0.5 15 6.1 0.1 2.3 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation zf-C3HC4_3 PF13920.6 KEG09850.1 - 0.16 11.8 12.9 0.28 11.1 12.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF5076 PF16826.5 KEG09851.1 - 0.1 12.5 0.0 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) Pkinase PF00069.25 KEG09853.1 - 3.9e-05 23.2 0.0 0.00035 20.0 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain CFAP91 PF14738.6 KEG09855.1 - 4.7e-42 143.6 8.9 4.7e-42 143.6 8.9 2.2 2 0 0 2 2 2 1 Cilia- and flagella-associated protein 91 DUF1514 PF07438.11 KEG09855.1 - 0.049 13.5 0.0 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) LpxI_N PF17930.1 KEG09856.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain T4bSS_IcmS PF12608.8 KEG09857.1 - 3.5e-17 62.5 2.5 8.8e-17 61.2 2.5 1.7 1 0 0 1 1 1 1 Type IVb secretion, IcmS, effector-recruitment DUF3439 PF11921.8 KEG09857.1 - 0.29 11.1 6.1 0.14 12.1 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) BUD22 PF09073.10 KEG09857.1 - 0.41 9.9 5.7 0.44 9.8 5.7 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KEG09857.1 - 2.4 6.2 5.1 3.1 5.8 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mucin PF01456.17 KEG09857.1 - 3.8 7.5 17.8 7.5 6.5 0.7 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Mucin PF01456.17 KEG09859.1 - 1.2e-05 25.3 15.7 7.4e-05 22.8 6.4 2.7 2 1 0 2 2 2 2 Mucin-like glycoprotein SSP160 PF06933.11 KEG09859.1 - 0.54 8.4 7.7 0.69 8.0 7.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 KEG09860.1 - 0.93 8.0 22.5 1.2 7.6 22.5 1.2 1 0 0 1 1 1 0 Macoilin family Enterotoxin_HS1 PF08090.11 KEG09860.1 - 1.6 8.7 9.5 6.3 6.8 6.4 2.6 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Mitofilin PF09731.9 KEG09860.1 - 8.8 5.0 33.1 11 4.7 33.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Aminotran_5 PF00266.19 KEG09863.1 - 1.9e-10 40.2 0.0 2.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEG09863.1 - 0.011 15.1 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEG09863.1 - 0.019 13.5 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GDP_Man_Dehyd PF16363.5 KEG09865.1 - 1.7e-72 244.7 0.1 1.9e-72 244.4 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEG09865.1 - 4e-55 186.9 0.1 4.9e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEG09865.1 - 5.2e-19 68.5 0.0 1.2e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEG09865.1 - 5.5e-18 65.1 0.0 7.7e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEG09865.1 - 3.3e-17 62.4 0.1 4.5e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEG09865.1 - 1.7e-15 56.9 1.1 9.6e-14 51.2 0.1 3.0 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.13 KEG09865.1 - 0.0039 16.8 0.1 0.012 15.2 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KEG09865.1 - 0.024 14.1 0.0 0.36 10.3 0.0 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KEG09865.1 - 0.028 14.3 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_2 PF03446.15 KEG09865.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_L38e PF01781.18 KEG09867.1 - 5.7e-29 100.0 5.9 6.8e-29 99.8 5.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF5320 PF17253.2 KEG09868.1 - 2.3 9.3 4.8 1.3 10.1 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) HlyIII PF03006.20 KEG09869.1 - 8.7e-19 68.1 12.1 1.1e-18 67.7 12.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Glycos_transf_1 PF00534.20 KEG09871.1 - 4e-10 39.5 0.0 2.6e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEG09871.1 - 2.7e-09 37.6 0.0 6.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEG09871.1 - 1.6e-06 28.4 0.4 1.8e-05 25.0 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Myc_target_1 PF15179.6 KEG09872.1 - 0.037 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 DUF4381 PF14316.6 KEG09872.1 - 0.14 12.4 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RRM_1 PF00076.22 KEG09873.1 - 1.7e-19 69.4 0.0 3.8e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG09873.1 - 0.11 12.7 0.0 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif TPR_12 PF13424.6 KEG09874.1 - 3e-61 203.6 50.8 1e-13 51.3 0.1 9.2 6 3 3 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 KEG09874.1 - 2.5e-39 132.1 40.3 2.5e-05 24.0 0.0 12.5 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_8 PF13181.6 KEG09874.1 - 4.4e-19 67.0 45.4 0.083 13.1 0.0 12.8 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEG09874.1 - 1.3e-18 65.5 55.2 0.04 14.0 0.2 12.6 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09874.1 - 2.6e-17 61.8 49.3 0.071 13.0 0.1 13.1 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KEG09874.1 - 8.2e-16 58.3 22.9 7.3e-07 28.9 4.1 3.8 1 1 0 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 KEG09874.1 - 2.4e-11 43.4 39.6 0.12 13.3 0.5 11.5 8 2 4 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEG09874.1 - 4.6e-11 41.9 33.9 0.15 12.2 0.0 10.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEG09874.1 - 1.4e-10 41.6 41.8 0.0077 16.9 0.6 8.6 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09874.1 - 0.00051 20.5 37.0 0.027 15.0 0.9 8.7 6 2 4 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09874.1 - 0.0043 16.7 7.0 6.9 6.4 0.1 6.2 5 1 0 5 5 5 1 TPR repeat TPR_3 PF07720.12 KEG09874.1 - 0.015 15.3 1.9 1.9 8.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KEG09874.1 - 0.081 13.0 19.6 0.49 10.5 0.5 6.5 4 2 1 6 6 6 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 KEG09874.1 - 3.2 7.9 16.0 18 5.5 0.0 5.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Exo_endo_phos PF03372.23 KEG09875.1 - 1.3e-11 44.5 0.0 2.6e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SUIM_assoc PF16619.5 KEG09875.1 - 0.76 9.9 16.1 4.6 7.4 12.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG09875.1 - 1.2 8.7 6.8 0.13 11.8 1.1 1.9 2 0 0 2 2 2 0 Spt20 family M_domain PF12938.7 KEG09875.1 - 1.5 8.6 13.4 3.4 7.4 7.7 2.2 2 0 0 2 2 2 0 M domain of GW182 Androgen_recep PF02166.16 KEG09875.1 - 1.8 7.3 6.9 0.58 8.9 1.7 2.0 2 0 0 2 2 2 0 Androgen receptor SET PF00856.28 KEG09877.1 - 4.9e-12 46.6 0.8 2.6e-08 34.4 0.0 3.3 3 1 0 3 3 3 2 SET domain FHA PF00498.26 KEG09878.1 - 0.012 15.9 0.0 0.064 13.6 0.0 2.3 2 1 0 2 2 2 0 FHA domain PA28_beta PF02252.18 KEG09879.1 - 4.9e-12 45.7 0.3 1.2e-08 34.8 0.2 2.5 3 0 0 3 3 3 2 Proteasome activator pa28 beta subunit CBS PF00571.28 KEG09881.1 - 0.00017 22.0 0.0 0.00024 21.5 0.0 1.2 1 0 0 1 1 1 1 CBS domain F-box-like PF12937.7 KEG09882.1 - 0.0075 16.1 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEG09882.1 - 0.036 14.0 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain RNase_H2_suC PF08615.11 KEG09883.1 - 8.5 6.5 7.6 2.1e+02 2.0 6.6 2.8 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AvrPto PF11592.8 KEG09885.1 - 0.012 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto AF-4 PF05110.13 KEG09886.1 - 0.015 13.4 1.9 0.016 13.4 1.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF488 PF04343.13 KEG09886.1 - 0.016 15.8 0.8 0.026 15.1 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF488 HTH_29 PF13551.6 KEG09886.1 - 0.035 14.1 0.1 0.082 12.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Synaptobrevin PF00957.21 KEG09886.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin HTH_28 PF13518.6 KEG09886.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1682 PF07946.14 KEG09886.1 - 1.6 7.8 9.1 1.3 8.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1682) PSP1 PF04468.12 KEG09888.1 - 2.6e-22 78.9 0.2 5.1e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region K_channel_TID PF07941.11 KEG09889.1 - 0.043 14.3 2.1 0.043 14.3 2.1 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Epimerase PF01370.21 KEG09891.1 - 3.1e-13 49.8 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEG09891.1 - 3.3e-06 26.4 0.0 6.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEG09891.1 - 6.5e-05 22.9 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding EF_TS PF00889.19 KEG09892.1 - 4.6e-13 49.3 0.2 8.1e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 Elongation factor TS BBS2_Mid PF14783.6 KEG09894.1 - 0.00018 21.5 0.0 0.0027 17.7 0.0 2.8 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 KEG09894.1 - 0.00083 18.2 0.1 0.13 11.0 0.0 2.5 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal PHTB1_N PF14727.6 KEG09894.1 - 0.0091 15.4 0.0 0.039 13.3 0.0 1.9 2 0 0 2 2 2 1 PTHB1 N-terminus FG-GAP PF01839.23 KEG09894.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 FG-GAP repeat Itfg2 PF15907.5 KEG09894.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 CLAMP PF14769.6 KEG09895.1 - 6.4e-06 26.5 0.0 0.00016 22.0 0.0 2.8 2 1 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 TyeA PF09059.10 KEG09895.1 - 0.015 15.4 0.4 0.25 11.5 0.1 2.6 2 0 0 2 2 2 0 TyeA Trp_DMAT PF11991.8 KEG09896.1 - 0.064 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase RRM_1 PF00076.22 KEG09897.1 - 1.5e-21 76.0 0.0 3.6e-11 42.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG09897.1 - 0.0021 17.6 0.0 3 7.5 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG09897.1 - 0.028 14.5 0.0 17 5.6 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 KEG09897.1 - 0.087 12.7 0.0 0.78 9.6 0.0 2.4 3 0 0 3 3 3 0 Occluded RNA-recognition motif AAA_6 PF12774.7 KEG09899.1 - 2e-156 520.0 0.1 3.3e-155 516.0 0.1 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG09899.1 - 6.7e-109 364.6 10.4 6.7e-109 364.6 10.4 4.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG09899.1 - 1.1e-99 333.0 0.1 9.2e-99 330.0 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KEG09899.1 - 2.8e-97 325.7 0.0 1.5e-96 323.3 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KEG09899.1 - 2.8e-84 281.7 0.1 2.8e-84 281.7 0.1 2.9 3 0 0 3 3 2 1 ATP-binding dynein motor region MT PF12777.7 KEG09899.1 - 5.1e-55 186.9 6.8 1.2e-54 185.6 6.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KEG09899.1 - 2.2e-54 183.7 0.4 1.4e-49 168.1 0.0 4.6 5 0 0 5 5 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG09899.1 - 1.6e-47 161.4 0.0 4.8e-47 159.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG09899.1 - 2.3e-41 140.6 0.0 4.3e-39 133.3 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KEG09899.1 - 1.1e-20 74.1 0.0 1.8e-05 24.7 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KEG09899.1 - 6.5e-20 71.5 0.4 6.7e-19 68.2 0.4 2.9 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KEG09899.1 - 1.6e-13 50.7 0.0 5.4e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KEG09899.1 - 1.5e-07 31.9 0.1 0.24 11.8 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG09899.1 - 0.00022 21.5 3.4 4.4 7.6 0.0 6.0 6 0 0 6 6 5 1 AAA domain NACHT PF05729.12 KEG09899.1 - 0.01 15.7 5.7 0.22 11.4 0.0 5.3 6 0 0 6 6 5 0 NACHT domain AAA_16 PF13191.6 KEG09899.1 - 0.014 15.8 13.3 2.3 8.5 0.0 7.6 7 2 0 7 7 7 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEG09899.1 - 0.014 14.7 0.4 6.7 6.0 0.0 3.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KEG09899.1 - 0.02 15.3 0.2 7.9 6.9 0.0 4.1 4 0 0 4 4 3 0 RNA helicase T2SSE PF00437.20 KEG09899.1 - 0.043 12.9 0.4 0.91 8.5 0.1 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 KEG09899.1 - 0.19 12.3 1.4 21 5.7 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 KEG09899.1 - 0.45 10.2 8.0 2.5 7.8 0.2 3.6 4 0 0 4 4 3 0 AAA domain Tnp_22_trimer PF17489.2 KEG09899.1 - 2.2 8.3 6.8 46 4.1 0.0 3.2 2 0 0 2 2 2 0 L1 transposable element trimerization domain HrpB7 PF09486.10 KEG09899.1 - 3.7 7.9 15.1 0.32 11.4 1.1 4.1 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 KEG09899.1 - 5.6 7.1 15.5 2.8 8.0 2.3 4.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HGD-D PF06050.13 KEG09899.1 - 7.8 6.2 7.7 3.2 7.4 0.0 3.5 4 0 0 4 4 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component Cauli_AT PF03233.13 KEG09899.1 - 9 6.2 10.6 1.8 8.5 1.0 3.9 3 0 0 3 3 3 0 Aphid transmission protein Flagellin_N PF00669.20 KEG09899.1 - 9.4 6.3 7.3 4.8 7.3 2.0 2.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DcpS_C PF11969.8 KEG09900.1 - 2.7e-06 27.9 0.1 8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Evr1_Alr PF04777.13 KEG09901.1 - 4.5e-14 52.7 0.2 1.1e-13 51.4 0.2 1.8 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 KEG09901.1 - 3e-10 40.0 0.1 5e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin FAD_SOX PF18371.1 KEG09901.1 - 0.0039 17.5 0.0 0.013 15.9 0.0 1.9 1 1 0 1 1 1 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF1491 PF07372.12 KEG09901.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) DUF2087 PF09860.9 KEG09901.1 - 0.11 12.7 0.0 0.44 10.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Peptidase_M8 PF01457.16 KEG09903.1 - 2.5e-121 406.0 2.2 1.3e-61 208.9 3.2 2.0 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG09903.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Cucumo_2B PF03263.13 KEG09903.1 - 0.13 12.7 0.1 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Cucumovirus protein 2B RRF PF01765.19 KEG09904.1 - 1.1e-17 64.5 1.6 1.9e-17 63.7 1.6 1.3 1 0 0 1 1 1 1 Ribosome recycling factor FAM92 PF06730.11 KEG09904.1 - 0.041 13.3 0.2 0.041 13.3 0.2 1.7 2 0 0 2 2 2 0 FAM92 protein IF4E PF01652.18 KEG09905.1 - 4.8e-25 88.2 0.0 7.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPP_enzyme_N PF02776.18 KEG09905.1 - 0.14 11.8 1.0 0.56 9.8 0.1 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain tRNA-synt_2 PF00152.20 KEG09907.1 - 8.8e-72 241.8 0.0 1.3e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEG09907.1 - 1e-06 28.6 0.1 2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEG09907.1 - 0.0028 17.2 0.2 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TAF4 PF05236.14 KEG09907.1 - 0.088 12.5 4.3 0.14 11.9 4.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SMC_N PF02463.19 KEG09909.1 - 2e-31 109.2 0.0 2.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEG09909.1 - 0.00042 20.2 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KEG09909.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MAJIN PF15077.6 KEG09909.1 - 0.065 13.0 3.2 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 Membrane-anchored junction protein PhyH PF05721.13 KEG09911.1 - 0.0003 21.1 0.0 0.0004 20.7 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RF-1 PF00472.20 KEG09912.1 - 4.2e-11 42.8 4.5 4.2e-11 42.8 4.5 3.9 3 1 1 4 4 4 1 RF-1 domain DUF2277 PF10041.9 KEG09912.1 - 0.0032 17.7 1.2 0.18 12.1 0.0 3.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) LAT PF15234.6 KEG09912.1 - 0.084 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Fez1 PF06818.15 KEG09912.1 - 1.1 9.7 33.1 2.3 8.6 21.8 3.3 2 1 0 3 3 3 0 Fez1 Caldesmon PF02029.15 KEG09912.1 - 3.5 6.3 26.7 3.3 6.4 3.0 2.2 2 0 0 2 2 2 0 Caldesmon zf-RING_2 PF13639.6 KEG09913.1 - 1.3e-12 47.8 8.2 1.9e-12 47.3 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG09913.1 - 4.5e-09 36.0 8.9 7.2e-09 35.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEG09913.1 - 6e-08 32.3 2.7 1.2e-07 31.3 2.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KEG09913.1 - 1e-07 32.2 9.7 2.5e-07 30.9 9.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KEG09913.1 - 2.4e-07 30.7 5.5 5.3e-07 29.6 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG09913.1 - 3.6e-06 26.7 7.3 6.2e-06 26.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG09913.1 - 4.3e-06 26.5 6.6 6.6e-06 25.9 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG09913.1 - 6.1e-06 26.2 1.6 8.5e-06 25.7 1.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KEG09913.1 - 1.1e-05 25.3 5.3 1.8e-05 24.6 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 KEG09913.1 - 0.0092 15.9 3.8 0.013 15.4 1.2 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 KEG09913.1 - 0.013 15.4 6.3 0.023 14.5 6.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KEG09913.1 - 0.021 14.4 5.2 0.034 13.8 5.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KEG09913.1 - 0.032 14.3 4.9 0.076 13.1 4.9 1.6 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 KEG09913.1 - 0.1 12.4 3.0 0.19 11.6 3.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KEG09913.1 - 0.1 12.8 7.6 0.18 12.0 7.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KEG09913.1 - 0.15 12.1 7.6 0.38 10.8 7.6 1.8 1 1 0 1 1 1 0 Zinc-finger DUF3426 PF11906.8 KEG09913.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Baculo_RING PF05883.11 KEG09913.1 - 0.2 11.6 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.29 KEG09913.1 - 0.24 11.3 5.4 0.47 10.4 5.4 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KEG09913.1 - 0.51 10.5 5.7 3.6 7.8 5.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KEG09913.1 - 1.9 8.3 6.9 4.3 7.2 6.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Synaptobrevin PF00957.21 KEG09914.1 - 1.1e-27 95.7 0.5 1.7e-27 95.0 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEG09914.1 - 0.0006 19.8 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain ubiquitin PF00240.23 KEG09914.1 - 0.13 12.1 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin family PPR_2 PF13041.6 KEG09916.1 - 3.5e-09 36.7 0.0 0.2 11.9 0.0 4.3 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.20 KEG09916.1 - 2.5e-05 24.2 0.4 2.3 8.7 0.3 4.4 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KEG09916.1 - 0.0035 17.4 0.0 3.5 7.8 0.0 3.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KEG09916.1 - 0.1 12.3 2.7 37 4.1 0.0 4.3 5 0 0 5 5 5 0 PPR repeat LRR_6 PF13516.6 KEG09917.1 - 1.1e-08 34.4 0.1 0.00016 21.4 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KEG09917.1 - 0.011 16.1 0.1 0.027 14.9 0.1 1.6 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG09917.1 - 0.012 16.1 0.1 5.9 7.9 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 KEG09917.1 - 0.045 13.5 0.4 0.42 10.4 0.3 2.4 2 1 0 2 2 2 0 Leucine rich repeat MscS_TM PF12794.7 KEG09918.1 - 6.1 5.6 6.3 12 4.6 6.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Complex1_LYR_2 PF13233.6 KEG09920.1 - 3.7e-12 46.8 1.2 5.3e-12 46.3 0.6 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KEG09920.1 - 0.0024 17.9 0.1 0.0043 17.1 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Phage_int_SAM_6 PF18644.1 KEG09920.1 - 0.21 11.6 0.0 0.37 10.8 0.0 1.4 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF4482 PF14818.6 KEG09921.1 - 0.0036 18.2 1.0 0.0036 18.2 1.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4482) ECH_2 PF16113.5 KEG09921.1 - 0.61 9.5 0.0 0.61 9.5 0.0 2.7 2 1 1 3 3 3 0 Enoyl-CoA hydratase/isomerase Atg14 PF10186.9 KEG09921.1 - 3.5 6.6 19.8 0.03 13.4 6.4 2.9 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Las1 PF04031.13 KEG09923.1 - 3.9e-30 105.0 0.1 6.2e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Las1-like Radial_spoke PF04712.12 KEG09923.1 - 0.11 11.4 5.0 0.16 10.9 5.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4632 PF15451.6 KEG09923.1 - 1.2 9.3 6.8 1.2 9.3 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) DSPc PF00782.20 KEG09926.1 - 5.8e-09 35.9 0.0 1.6e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG09926.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KEG09926.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Mid2 PF04478.12 KEG09926.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Radical_SAM_C PF16199.5 KEG09927.1 - 5.8e-19 67.9 0.0 1.2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KEG09927.1 - 2.9e-15 57.1 0.0 7.4e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KEG09927.1 - 4e-08 33.5 0.3 3.5e-07 30.4 0.2 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG09927.1 - 0.00023 21.1 0.1 0.0007 19.5 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Herpes_UL7 PF01677.16 KEG09927.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL7 like Hydrolase_4 PF12146.8 KEG09930.1 - 4.5e-14 52.3 1.3 2.9e-07 30.0 0.3 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEG09930.1 - 1.1e-08 34.8 0.3 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank_4 PF13637.6 KEG09930.1 - 2.7e-08 34.2 0.1 3.3e-07 30.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEG09930.1 - 5.4e-08 32.9 0.1 3.6e-07 30.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG09930.1 - 5.5e-08 33.3 0.2 2.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Abhydrolase_6 PF12697.7 KEG09930.1 - 7.5e-08 33.2 0.2 1.6e-07 32.2 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KEG09930.1 - 6.9e-07 29.1 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KEG09930.1 - 7.4e-07 29.1 0.2 4.9e-05 23.1 0.2 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Ank PF00023.30 KEG09930.1 - 6.5e-05 23.2 0.2 0.022 15.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat AXE1 PF05448.12 KEG09930.1 - 0.00014 20.7 0.9 0.035 12.8 0.7 2.6 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Ank_3 PF13606.6 KEG09930.1 - 0.0002 21.6 0.0 0.003 17.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Spexin PF15171.6 KEG09930.1 - 0.094 12.9 1.4 0.21 11.8 1.4 1.5 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin DUF3384 PF11864.8 KEG09931.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Sld7_C PF18596.1 KEG09931.1 - 0.13 12.4 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 Sld7 C-terminal domain Aminotran_1_2 PF00155.21 KEG09932.1 - 8.5e-78 262.1 0.0 9.6e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PriC PF07445.12 KEG09933.1 - 0.032 14.1 3.7 0.13 12.2 3.7 2.0 1 1 0 1 1 1 0 Primosomal replication protein priC CPSF73-100_C PF11718.8 KEG09934.1 - 0.12 11.9 2.7 0.48 9.9 0.4 2.1 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term YppG PF14179.6 KEG09934.1 - 2.2 9.0 9.1 0.77 10.5 4.0 2.4 2 0 0 2 2 2 0 YppG-like protein Actin PF00022.19 KEG09935.1 - 7.4e-80 268.5 0.0 9.4e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Actin GOLGA2L5 PF15070.6 KEG09936.1 - 0.046 12.4 14.0 0.065 11.9 14.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 KEG09936.1 - 0.049 13.4 0.7 0.049 13.4 0.7 2.3 3 0 0 3 3 3 0 Septum formation initiator SlyX PF04102.12 KEG09936.1 - 2.8 8.6 13.9 0.24 12.1 1.9 3.9 2 2 0 3 3 3 0 SlyX RrnaAD PF00398.20 KEG09937.1 - 1.1e-24 87.0 0.0 2.6e-13 49.7 0.0 2.0 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KEG09937.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEG09937.1 - 0.15 12.8 0.0 0.62 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CBS PF00571.28 KEG09938.1 - 8.1e-05 23.0 3.5 0.0025 18.2 1.4 2.2 2 0 0 2 2 2 2 CBS domain FAD-oxidase_C PF02913.19 KEG09939.1 - 4.6e-33 114.9 0.1 5e-33 114.8 0.1 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEG09940.1 - 6.7e-36 123.1 0.7 9.5e-36 122.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FHA PF00498.26 KEG09941.1 - 4.2e-10 39.8 0.0 5.4e-09 36.3 0.0 2.6 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEG09941.1 - 0.032 14.6 0.0 8.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain STI1 PF17830.1 KEG09942.1 - 2.1e-12 46.7 6.4 4.7e-12 45.6 6.4 1.5 1 0 0 1 1 1 1 STI1 domain TPR_2 PF07719.17 KEG09942.1 - 3.2e-07 29.9 1.3 0.05 13.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG09942.1 - 1.2e-05 25.4 0.2 4.2e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG09942.1 - 3.6e-05 23.4 0.1 0.057 13.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG09942.1 - 0.00031 21.3 5.4 0.027 15.1 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG09942.1 - 0.0037 17.5 8.2 0.044 14.1 1.9 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CDC45 PF02724.14 KEG09942.1 - 0.0069 14.7 0.9 0.0092 14.3 0.9 1.1 1 0 0 1 1 1 1 CDC45-like protein TPR_17 PF13431.6 KEG09942.1 - 0.0085 16.4 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG09942.1 - 0.0099 16.4 3.1 1.5 9.4 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Rrn6 PF10214.9 KEG09942.1 - 0.01 14.4 2.5 0.013 14.1 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TPR_14 PF13428.6 KEG09942.1 - 0.012 16.4 11.1 0.29 12.0 0.1 4.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG09942.1 - 0.026 14.2 0.0 14 5.4 0.0 3.0 2 1 1 3 3 3 0 TPR repeat HipN PF18253.1 KEG09942.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain ChAPs PF09295.10 KEG09942.1 - 0.033 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2999 PF11212.8 KEG09942.1 - 0.038 14.3 0.6 0.075 13.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) NARP1 PF12569.8 KEG09942.1 - 0.16 10.9 0.0 0.16 10.9 0.0 2.2 1 1 1 2 2 1 0 NMDA receptor-regulated protein 1 MRVI1 PF05781.12 KEG09942.1 - 0.29 9.8 6.2 0.42 9.2 6.2 1.2 1 0 0 1 1 1 0 MRVI1 protein DUF2828 PF11443.8 KEG09942.1 - 0.45 8.5 5.6 0.63 8.1 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 KEG09942.1 - 2.8 6.6 4.8 3.9 6.1 4.8 1.1 1 0 0 1 1 1 0 Presenilin Keratin_2_head PF16208.5 KEG09942.1 - 5.5 7.1 17.2 0.48 10.6 12.6 1.5 2 0 0 2 2 1 0 Keratin type II head ArfGap PF01412.18 KEG09943.1 - 1.2e-37 128.5 1.0 1.2e-37 128.5 1.0 2.1 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf Emaravirus_P4 PF16505.5 KEG09943.1 - 0.048 12.7 0.1 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Chorion_2 PF03964.15 KEG09943.1 - 0.26 12.2 4.5 4.6 8.1 0.3 2.3 2 0 0 2 2 2 0 Chorion family 2 UBA_4 PF14555.6 KEG09944.1 - 5.4e-07 29.3 0.3 1.3e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 UBA-like domain zf-met PF12874.7 KEG09946.1 - 0.005 17.2 0.4 0.0089 16.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 KEG09946.1 - 0.051 13.8 0.2 0.083 13.1 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) C2 PF00168.30 KEG09947.1 - 0.0031 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain Radial_spoke_3 PF06098.11 KEG09948.1 - 4.8e-108 360.8 27.4 5.9e-108 360.5 27.4 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 ARGLU PF15346.6 KEG09948.1 - 0.39 10.6 38.7 0.02 14.8 19.9 2.7 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Peptidase_C2 PF00648.21 KEG09949.1 - 2.4e-20 72.7 0.0 3.8e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Kre28 PF17097.5 KEG09949.1 - 1.1e-07 31.2 45.6 0.26 10.2 0.1 15.4 17 0 0 17 17 17 8 Spindle pole body component Calpain_III PF01067.22 KEG09949.1 - 4.3e-06 27.0 0.0 1.7e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Calpain large subunit, domain III DUF3470 PF11953.8 KEG09949.1 - 1.2 9.1 3.6 57 3.8 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3470) TetR_C_24 PF17932.1 KEG09949.1 - 3.1 8.1 8.6 19 5.5 0.1 5.7 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain UTP25 PF06862.12 KEG09950.1 - 1.6e-40 139.3 1.6 1.8e-40 139.1 1.6 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Dzip-like_N PF13815.6 KEG09951.1 - 5.1e-41 139.3 2.7 5.1e-41 139.3 2.7 2.6 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 KEG09951.1 - 0.00026 21.3 0.9 0.00058 20.2 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEG09951.1 - 0.00077 20.1 1.1 0.0024 18.6 0.9 1.9 2 0 0 2 2 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 KEG09951.1 - 0.0056 16.9 0.9 0.012 15.9 0.9 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Spc29 PF17082.5 KEG09951.1 - 0.013 15.3 4.2 3.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Spindle Pole Component 29 KASH_CCD PF14662.6 KEG09951.1 - 0.016 15.0 1.1 0.016 15.0 1.1 2.9 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH VGPC1_C PF16799.5 KEG09951.1 - 0.025 14.6 0.9 0.066 13.2 0.9 1.6 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF2972 PF11186.8 KEG09951.1 - 0.095 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) zf-C2H2_2 PF12756.7 KEG09951.1 - 0.11 12.9 2.6 0.35 11.2 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 KEG09951.1 - 0.24 12.1 7.1 0.041 14.6 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.6 KEG09951.1 - 0.36 10.9 1.1 0.71 9.9 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEG09951.1 - 0.44 11.1 2.7 6.3 7.4 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain YabA PF06156.13 KEG09951.1 - 1.4 9.6 8.7 13 6.5 0.0 2.9 3 0 0 3 3 3 0 Initiation control protein YabA GIT_CC PF16559.5 KEG09951.1 - 1.4 8.8 13.5 4.4 7.2 0.1 3.8 4 0 0 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 KEG09951.1 - 1.9 9.0 15.0 8.4 6.9 0.0 3.5 3 0 0 3 3 3 0 Cell division protein ZapB FliD_N PF02465.18 KEG09951.1 - 2.8 8.7 14.3 1.6 9.5 3.8 3.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BLOC1_2 PF10046.9 KEG09951.1 - 5.3 7.4 8.9 35 4.8 0.1 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 KEG09951.1 - 5.6 4.8 9.8 13 3.5 9.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family mRNA_triPase PF02940.15 KEG09952.1 - 7.9e-10 38.8 0.0 1.4e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.14 KEG09953.1 - 3.6e-14 52.7 0.0 2.8e-11 43.2 0.0 2.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEG09953.1 - 2.6e-09 37.5 0.0 4.7e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEG09953.1 - 0.00024 20.8 0.0 0.48 9.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEG09953.1 - 0.0012 18.0 0.0 0.72 8.8 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KEG09953.1 - 0.0067 16.8 0.0 0.97 9.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KEG09953.1 - 0.011 16.0 0.0 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KEG09953.1 - 0.033 14.2 0.0 0.084 12.9 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 KEG09953.1 - 0.053 12.7 0.0 0.87 8.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KEG09953.1 - 0.064 13.1 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KEG09953.1 - 0.16 12.0 0.0 5.5 7.0 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding F-box PF00646.33 KEG09954.1 - 0.0024 17.7 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEG09954.1 - 0.023 14.6 0.5 0.054 13.4 0.1 1.9 2 0 0 2 2 2 0 F-box-like Importin_rep_4 PF18808.1 KEG09954.1 - 0.069 13.4 1.0 0.14 12.5 1.0 1.4 1 0 0 1 1 1 0 Importin repeat CS PF04969.16 KEG09955.1 - 9.6e-17 61.8 0.0 1.9e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 KEG09955.1 - 1.3e-13 50.7 0.4 2.9e-13 49.6 0.4 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CppA_C PF14507.6 KEG09955.1 - 0.046 14.5 2.6 2.7 8.8 0.6 3.2 2 1 0 2 2 2 0 CppA C-terminal PRMT5 PF05185.16 KEG09955.1 - 0.092 12.6 0.5 0.3 10.9 0.2 1.9 1 1 1 2 2 2 0 PRMT5 arginine-N-methyltransferase MerR-DNA-bind PF09278.11 KEG09955.1 - 2.6 8.6 8.8 17 6.0 0.1 2.9 3 0 0 3 3 3 0 MerR, DNA binding DUF3987 PF13148.6 KEG09955.1 - 5 6.0 12.9 8.3 5.3 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ARGLU PF15346.6 KEG09955.1 - 6.7 6.6 20.5 4 7.3 15.3 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Cys_Met_Meta_PP PF01053.20 KEG09956.1 - 1.9e-116 388.7 0.0 2.4e-116 388.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEG09956.1 - 4.2e-06 26.2 0.0 6.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEG09956.1 - 0.00029 19.9 0.1 0.00047 19.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEG09956.1 - 0.043 13.1 0.2 0.14 11.4 0.2 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SlyX PF04102.12 KEG09956.1 - 0.056 14.1 0.0 0.29 11.8 0.0 2.3 1 0 0 1 1 1 0 SlyX UDPGT PF00201.18 KEG09957.1 - 1.3e-24 86.9 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEG09957.1 - 0.0037 17.3 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SPRY PF00622.28 KEG09958.1 - 3.4e-07 30.4 0.0 1.1e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 SPRY domain DUF563 PF04577.14 KEG09962.1 - 2e-20 73.9 0.5 3.8e-20 72.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Lipoprotein_7 PF01540.16 KEG09964.1 - 0.018 14.4 0.2 0.02 14.2 0.2 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein SSXT PF05030.12 KEG09964.1 - 0.019 14.6 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) ERM PF00769.19 KEG09964.1 - 0.024 14.5 8.4 0.031 14.1 8.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ParD PF09386.10 KEG09964.1 - 0.07 13.5 1.6 11 6.5 0.8 2.5 2 0 0 2 2 2 0 Antitoxin ParD HXXSHH PF07586.11 KEG09964.1 - 0.073 12.6 2.2 0.083 12.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Trep_dent_lipo PF09710.10 KEG09964.1 - 0.073 12.0 0.4 0.082 11.8 0.4 1.0 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Gene66 PF02053.15 KEG09964.1 - 0.095 12.3 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Gene 66 (IR5) protein Apolipoprotein PF01442.18 KEG09964.1 - 0.11 12.4 13.4 0.46 10.3 13.4 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.19 KEG09964.1 - 0.2 9.5 2.6 0.22 9.4 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KEG09964.1 - 0.47 10.5 4.3 0.68 10.0 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KEG09964.1 - 1.5 9.5 7.3 8.6 7.1 4.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Glyco_hydro_65m PF03632.15 KEG09965.1 - 3e-69 233.7 0.0 4.5e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KEG09965.1 - 6.2e-34 117.6 0.3 1.2e-33 116.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 KEG09965.1 - 1.1e-07 31.6 0.0 3.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.6 KEG09965.1 - 1.5e-07 31.6 0.0 4.4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase LEM PF03020.15 KEG09965.1 - 0.19 11.3 0.1 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 LEM domain PRKCSH PF07915.13 KEG09967.1 - 3e-11 44.2 0.0 2.2e-10 41.4 0.0 2.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KEG09967.1 - 0.014 15.1 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Adaptin_N PF01602.20 KEG09970.1 - 1.2e-73 248.5 0.5 1.6e-73 248.1 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 KEG09970.1 - 2.2e-22 79.3 0.9 5.4e-22 78.0 0.9 1.7 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.6 KEG09970.1 - 1.5e-06 28.5 4.7 0.053 13.9 0.2 4.4 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 KEG09970.1 - 2.8e-06 27.5 1.3 0.11 12.5 0.9 2.8 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KEG09970.1 - 0.0029 18.1 4.5 0.38 11.3 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat Cnd3 PF12719.7 KEG09970.1 - 0.0095 15.2 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 KEG09970.1 - 0.014 14.9 0.8 0.034 13.7 0.1 2.0 2 0 0 2 2 2 0 CLASP N terminal B2-adapt-app_C PF09066.10 KEG09970.1 - 0.019 15.1 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 KEG09970.1 - 0.14 12.5 9.5 46 4.6 0.2 5.5 5 0 0 5 5 5 0 HEAT repeat Melibiase PF02065.18 KEG09970.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Melibiase C6 PF01681.17 KEG09970.1 - 6.2 7.4 6.9 1.1 9.9 1.5 2.4 2 0 0 2 2 2 0 C6 domain Flavoprotein PF02441.19 KEG09972.1 - 1.8e-47 161.0 0.0 7.5e-46 155.8 0.0 2.0 1 1 0 1 1 1 1 Flavoprotein AAA PF00004.29 KEG09973.1 - 5.6e-13 49.5 0.0 1.8e-12 47.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG09973.1 - 1.1e-05 25.9 0.0 2.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEG09973.1 - 5.1e-05 23.3 0.0 8.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG09973.1 - 0.0014 18.4 0.0 0.0071 16.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KEG09973.1 - 0.003 17.4 0.8 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEG09973.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KEG09973.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KEG09973.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KEG09973.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KEG09973.1 - 0.023 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEG09973.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEG09973.1 - 0.033 14.6 0.0 0.097 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KEG09973.1 - 0.037 14.3 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG09973.1 - 0.04 14.5 0.0 0.099 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KEG09973.1 - 0.045 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KEG09973.1 - 0.046 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KEG09973.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KEG09973.1 - 0.088 11.9 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 KEG09973.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 KEG09973.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC cobW PF02492.19 KEG09973.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PPV_E1_C PF00519.17 KEG09973.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_16 PF13191.6 KEG09974.1 - 0.044 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PseudoU_synth_2 PF00849.22 KEG09975.1 - 5.6e-37 127.3 0.0 9.3e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Abhydrolase_1 PF00561.20 KEG09977.1 - 0.00044 20.0 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold EF-hand_13 PF17958.1 KEG09978.1 - 1.1e-25 89.3 0.1 2.7e-25 88.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KEG09978.1 - 4.4e-20 71.9 1.2 1.9e-15 57.0 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG09978.1 - 4e-07 29.4 0.4 0.00077 19.2 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KEG09978.1 - 3.7e-05 23.0 0.6 0.028 14.0 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KEG09978.1 - 0.00065 19.1 0.0 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KEG09978.1 - 0.0039 17.0 0.1 5.6 6.9 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_11 PF08976.11 KEG09978.1 - 0.079 13.8 0.1 0.18 12.7 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain GRAM PF02893.20 KEG09979.1 - 5.3e-25 87.5 2.0 2.1e-12 46.9 0.2 2.4 2 0 0 2 2 2 2 GRAM domain VASt PF16016.5 KEG09979.1 - 3.3e-15 56.8 0.0 7.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain adh_short PF00106.25 KEG09982.1 - 3.9e-56 189.6 0.6 5.2e-56 189.2 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG09982.1 - 4.4e-50 170.4 1.5 6.9e-50 169.8 1.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG09982.1 - 7.9e-16 58.5 0.4 1.3e-15 57.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEG09982.1 - 0.00029 20.4 0.2 0.00063 19.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 KEG09982.1 - 0.0013 18.2 2.4 0.0018 17.7 0.6 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme GDP_Man_Dehyd PF16363.5 KEG09982.1 - 0.005 16.3 0.1 0.0093 15.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KEG09982.1 - 0.036 13.7 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Beta_helix PF13229.6 KEG09983.1 - 1.3e-19 70.6 3.3 9.3e-05 22.3 3.2 7.9 5 2 1 6 6 6 6 Right handed beta helix region DGF-1_5 PF11038.8 KEG09984.1 - 2.1e-135 450.5 14.4 2.1e-135 450.5 14.4 2.8 3 0 0 3 3 3 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DGF-1_4 PF11024.8 KEG09984.1 - 9.8e-17 61.5 20.8 9.8e-17 61.5 20.8 3.4 2 1 1 3 3 3 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 DGF-1_C PF11040.8 KEG09984.1 - 9.8e-16 57.5 0.9 2.7e-15 56.1 0.9 1.7 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Snapin_Pallidin PF14712.6 KEG09986.1 - 0.00014 22.3 0.1 0.00014 22.3 0.1 2.1 2 0 0 2 2 2 1 Snapin/Pallidin SUIM_assoc PF16619.5 KEG09987.1 - 0.21 11.7 2.4 0.86 9.7 2.4 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PAC4 PF16093.5 KEG09990.1 - 8.8e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Cyt-b5 PF00173.28 KEG09991.1 - 1e-39 134.5 0.4 7.5e-21 74.1 0.1 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Synaptobrevin PF00957.21 KEG09991.1 - 0.26 11.1 1.2 0.27 11.0 0.1 1.6 2 0 0 2 2 2 0 Synaptobrevin Hist_deacetyl PF00850.19 KEG09992.1 - 1.3e-23 84.0 0.1 2.2e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain CBP_BcsO PF17037.5 KEG09992.1 - 0.011 16.0 1.5 0.017 15.3 1.5 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Hist_deacetyl PF00850.19 KEG09993.1 - 4e-28 98.8 0.0 5.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RNase_PH PF01138.21 KEG09994.1 - 2.1e-19 70.3 0.9 3.7e-19 69.5 0.0 1.8 3 0 0 3 3 3 1 3' exoribonuclease family, domain 1 SNAP PF14938.6 KEG09995.1 - 2.5e-27 96.0 9.2 4.3e-27 95.3 9.2 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DHR-2 PF06920.13 KEG09995.1 - 0.00032 19.5 1.6 0.00049 18.9 1.6 1.3 1 0 0 1 1 1 1 Dock homology region 2 TPR_12 PF13424.6 KEG09995.1 - 0.0042 17.3 10.2 0.22 11.8 1.4 3.6 2 2 2 4 4 4 3 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KEG09995.1 - 0.007 16.0 3.0 0.2 11.2 0.1 2.3 1 1 1 2 2 2 2 Foie gras liver health family 1 PPR PF01535.20 KEG09995.1 - 0.13 12.6 0.7 1.8 9.0 0.0 3.2 3 0 0 3 3 3 0 PPR repeat KN17_SH3 PF18131.1 KEG09996.1 - 0.013 15.6 0.0 0.075 13.2 0.1 2.1 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain PTS_2-RNA PF01885.16 KEG09998.1 - 9.4e-57 192.0 0.0 1.8e-56 191.0 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.24 KEG09998.1 - 1.4e-22 81.0 0.0 2.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.18 KEG09999.1 - 1.7e-62 211.6 0.0 2.4e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.14 KEG09999.1 - 1.3e-14 54.3 0.0 4.2e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Beta_helix_2 PF18835.1 KEG09999.1 - 0.14 11.9 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase HTH_54 PF18607.1 KEG10001.1 - 0.011 15.7 2.3 0.73 9.9 0.1 2.9 2 0 0 2 2 2 0 ParA helix turn helix domain DUF1677 PF07911.13 KEG10001.1 - 0.32 11.4 0.2 0.32 11.4 0.2 4.5 3 3 2 5 5 5 0 Protein of unknown function (DUF1677) Glyoxalase_5 PF14696.6 KEG10001.1 - 1.6 8.9 4.9 0.3 11.3 0.6 2.1 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TSP_NTD PF17804.1 KEG10002.1 - 0.44 10.8 3.4 0.29 11.4 1.5 1.7 2 0 0 2 2 2 0 Tail specific protease N-terminal domain zf-CCHC PF00098.23 KEG10003.1 - 2.3e-49 163.3 69.6 2.3e-08 33.7 3.1 8.1 8 0 0 8 8 8 8 Zinc knuckle zf-CCHC_4 PF14392.6 KEG10003.1 - 8.2e-10 38.3 44.2 0.035 13.8 0.3 8.0 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_2 PF13696.6 KEG10003.1 - 1.1e-07 31.5 73.4 0.0063 16.3 1.0 8.3 8 0 0 8 8 8 6 Zinc knuckle zf-CCHC_5 PF14787.6 KEG10003.1 - 3.1e-07 30.0 50.5 0.011 15.4 1.4 7.5 7 1 0 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KEG10003.1 - 7.2e-07 29.1 50.6 0.4 10.7 0.4 8.0 1 1 7 8 8 8 7 Zinc knuckle zf-CCHC_6 PF15288.6 KEG10003.1 - 0.0011 18.7 3.0 0.0011 18.7 3.0 7.7 7 1 1 8 8 8 3 Zinc knuckle zf-CCHC PF00098.23 KEG10004.1 - 1.3e-36 123.0 31.0 1.2e-09 37.8 1.9 4.1 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 KEG10004.1 - 9.9e-13 47.8 16.8 0.0012 18.8 0.7 4.1 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KEG10004.1 - 1.4e-08 34.4 25.5 0.0049 16.7 1.4 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 KEG10004.1 - 1.5e-08 34.3 18.6 0.036 13.8 0.5 4.1 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_6 PF15288.6 KEG10004.1 - 0.0033 17.2 30.5 0.13 12.1 1.3 4.2 4 0 0 4 4 4 3 Zinc knuckle DZR PF12773.7 KEG10004.1 - 0.051 13.6 20.3 21 5.2 8.6 3.1 1 1 1 2 2 2 0 Double zinc ribbon zf-CCHC_5 PF14787.6 KEG10004.1 - 0.06 13.1 22.5 2.1 8.1 0.2 4.1 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger zf-ribbon_3 PF13248.6 KEG10004.1 - 0.56 9.7 0.2 0.2 11.1 1.7 5.2 8 0 0 8 8 8 0 zinc-ribbon domain IBR PF01485.21 KEG10004.1 - 2.5 8.4 18.6 10 6.4 0.2 4.2 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf-Mss51 PF13824.6 KEG10004.1 - 5.8 7.1 16.8 9.9 6.4 1.1 3.5 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Proteasome PF00227.26 KEG10005.1 - 2.4e-49 167.4 0.3 2.9e-49 167.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.25 KEG10006.1 - 4.1e-05 23.2 0.1 0.00027 20.6 0.1 2.2 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 KEG10006.1 - 4.5e-05 23.6 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Q_salvage PF10343.9 KEG10007.1 - 2.4e-16 60.1 0.0 3e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family EBP50_C PF09007.11 KEG10008.1 - 1.5 9.8 8.1 1 10.3 0.5 2.7 2 0 0 2 2 2 0 EBP50, C-terminal Peptidase_M76 PF09768.9 KEG10009.1 - 1.1e-50 171.8 0.8 1.3e-50 171.6 0.8 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 KEG10009.1 - 0.0022 18.3 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 Effector protein Tox-MPTase2 PF15638.6 KEG10009.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 DEK_C PF08766.11 KEG10011.1 - 0.00083 19.2 1.1 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 DEK C terminal domain Ribosomal_S27 PF01599.19 KEG10013.1 - 2.5e-23 82.0 2.7 5.6e-23 80.8 2.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 KEG10013.1 - 5.1e-07 29.4 1.5 3.9e-06 26.5 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KEG10013.1 - 0.00041 20.1 0.1 0.017 15.0 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 KEG10013.1 - 0.00099 19.3 0.3 0.0019 18.4 0.3 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DnaJ PF00226.31 KEG10014.1 - 1.6e-20 73.0 0.5 3.5e-20 71.9 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DUF5327 PF17261.2 KEG10014.1 - 0.087 13.6 3.0 0.11 13.2 0.5 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5327) ATP-synt_Eps PF04627.13 KEG10015.1 - 3.5e-09 36.5 0.2 4.5e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.8 KEG10016.1 - 3.1e-20 72.8 0.5 3.6e-20 72.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) DUF4944 PF16302.5 KEG10016.1 - 0.0064 16.6 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4944) RNase_HII PF01351.18 KEG10017.1 - 8.4e-42 143.3 0.0 1.2e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.13 KEG10018.1 - 2.2e-07 30.3 6.0 5.7e-05 22.3 0.3 2.3 1 1 0 2 2 2 2 GPI transamidase subunit PIG-U Cmc1 PF08583.10 KEG10019.1 - 1.2 9.2 5.6 5.7 7.0 1.3 3.0 2 2 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like GlcNAc PF11397.8 KEG10020.1 - 2.3e-26 93.1 0.0 3.8e-15 56.2 0.1 3.5 2 2 0 2 2 2 2 Glycosyltransferase (GlcNAc) Vps51 PF08700.11 KEG10021.1 - 5.8e-12 45.5 0.5 5.8e-12 45.5 0.5 2.3 2 0 0 2 2 2 1 Vps51/Vps67 zf-C3HC4_3 PF13920.6 KEG10022.1 - 2.1e-14 53.1 5.0 4.5e-14 52.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 KEG10022.1 - 7.1e-08 32.9 0.0 1.8e-06 28.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG10022.1 - 1.1e-07 32.2 0.0 5.6e-06 26.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 KEG10022.1 - 2.2e-07 30.6 5.2 5e-07 29.5 5.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_3 PF13606.6 KEG10022.1 - 3.7e-07 29.9 0.0 0.01 16.3 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat zf-RING_2 PF13639.6 KEG10022.1 - 3.1e-06 27.4 5.9 8.4e-06 26.0 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEG10022.1 - 6.9e-05 22.6 5.4 0.00014 21.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 KEG10022.1 - 0.00036 20.8 0.2 0.018 15.4 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeat zf-C3HC4_2 PF13923.6 KEG10022.1 - 0.003 17.4 6.6 0.0076 16.1 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 KEG10022.1 - 0.0049 17.1 0.2 2.9 8.3 0.1 3.0 2 1 1 3 3 2 2 Ankyrin repeats (many copies) zf-RING_5 PF14634.6 KEG10022.1 - 0.0064 16.4 4.5 0.0064 16.4 4.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG10022.1 - 0.051 13.6 3.2 0.18 11.8 3.2 2.1 1 0 0 1 1 1 0 RING-type zinc-finger UEV PF05743.13 KEG10022.1 - 0.061 13.2 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 UEV domain GDPD PF03009.17 KEG10023.1 - 1.8e-34 119.7 0.0 1.9e-31 109.7 0.0 3.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DDE_Tnp_1_6 PF13751.6 KEG10024.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain RPA_interact_C PF14768.6 KEG10025.1 - 0.87 10.2 5.0 0.8 10.3 0.3 3.5 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Bacillus_HBL PF05791.11 KEG10025.1 - 1.7 8.4 12.3 0.53 10.1 3.7 3.4 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.8 KEG10025.1 - 5.9 4.3 56.5 0.18 9.3 3.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Ribosomal_L21p PF00829.21 KEG10026.1 - 8.1e-21 74.2 0.1 1.2e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Solute_trans_a PF03619.16 KEG10027.1 - 3.7e-69 233.2 20.7 1.9e-68 230.9 20.7 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Ras PF00071.22 KEG10028.1 - 5.3e-41 139.9 0.0 6.9e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG10028.1 - 6.3e-27 94.2 0.0 9.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG10028.1 - 7.3e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEG10028.1 - 0.01 15.7 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KEG10028.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.23 KEG10028.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KEG10028.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KEG10028.1 - 0.19 11.2 0.0 0.4 10.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KEG10028.1 - 0.23 10.8 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SUIM_assoc PF16619.5 KEG10032.1 - 0.076 13.1 2.5 0.11 12.5 0.4 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATG16 PF08614.11 KEG10032.1 - 0.16 12.2 11.1 0.51 10.5 11.1 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MMM1 PF10296.9 KEG10035.1 - 4.9e-06 25.8 0.0 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 IQCJ-SCHIP1 PF15157.6 KEG10035.1 - 0.74 9.6 2.6 2 8.3 0.0 2.6 3 0 0 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif COQ9 PF08511.11 KEG10037.1 - 7.9e-06 25.6 0.0 0.0016 18.2 0.0 2.7 3 0 0 3 3 3 2 COQ9 DUF1496 PF07383.12 KEG10037.1 - 0.0035 16.9 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) DUF202 PF02656.15 KEG10038.1 - 2.2e-17 63.3 1.1 6.5e-16 58.5 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Clc-like PF07062.12 KEG10038.1 - 0.21 11.1 0.8 0.29 10.6 0.8 1.3 1 1 0 1 1 1 0 Clc-like SLATT_5 PF18160.1 KEG10038.1 - 1.8 7.9 3.9 0.39 10.0 0.4 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Sulfotransfer_3 PF13469.6 KEG10039.1 - 2e-09 38.2 0.0 3.1e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Mito_carr PF00153.27 KEG10042.1 - 6.3e-13 48.5 3.7 4.8e-06 26.4 0.0 3.2 3 1 0 3 3 3 2 Mitochondrial carrier protein AHJR-like PF18743.1 KEG10042.1 - 0.22 11.1 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 REase_AHJR-like Mito_carr PF00153.27 KEG10043.1 - 1.1e-26 92.6 2.6 4.4e-12 45.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein BLUF PF04940.12 KEG10046.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.5 1 1 0 1 1 1 0 Sensors of blue-light using FAD Pro_isomerase PF00160.21 KEG10047.1 - 1.1e-16 61.5 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.16 KEG10048.1 - 1.6e-16 60.3 0.0 9.6e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component MipZ PF09140.11 KEG10048.1 - 0.077 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ GTP_EFTU PF00009.27 KEG10049.1 - 6.9e-18 64.9 0.1 1.2e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG10049.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG10049.1 - 0.042 13.7 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KEG10049.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KEG10049.1 - 0.11 12.3 0.2 0.32 10.7 0.2 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KEG10049.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IQ PF00612.27 KEG10050.1 - 4.6e-19 66.4 39.0 0.0003 20.3 0.8 7.8 7 0 0 7 7 7 6 IQ calmodulin-binding motif TPR_2 PF07719.17 KEG10050.1 - 0.065 13.4 2.9 1.5 9.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KEG10051.1 - 1.6e-11 44.1 0.1 1e-10 41.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain F-box PF00646.33 KEG10051.1 - 0.0064 16.3 0.3 0.019 14.8 0.3 1.9 1 0 0 1 1 1 1 F-box domain FYVE_2 PF02318.16 KEG10051.1 - 0.1 12.8 2.4 0.31 11.3 2.4 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Dymeclin PF09742.9 KEG10052.1 - 5.9e-75 252.9 0.0 7.3e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KEG10052.1 - 1.2e-44 152.7 0.0 2.1e-41 142.0 0.0 3.0 2 1 0 2 2 2 2 High-temperature-induced dauer-formation protein MotB_plug PF13677.6 KEG10052.1 - 0.012 15.2 0.3 0.03 13.9 0.3 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB zf-C3HC4_2 PF13923.6 KEG10053.1 - 5e-09 35.9 11.1 5e-09 35.9 11.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG10053.1 - 1.7e-08 34.2 6.7 1.7e-08 34.2 6.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG10053.1 - 6.2e-08 32.5 6.5 6.2e-08 32.5 6.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEG10053.1 - 1.2e-06 28.4 9.7 1.2e-06 28.4 9.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KEG10053.1 - 2.6e-06 27.6 9.5 2.6e-06 27.6 9.5 2.1 2 0 0 2 2 2 1 Ring finger domain DZR PF12773.7 KEG10053.1 - 2.7e-05 24.1 11.3 0.052 13.6 3.9 2.4 1 1 1 2 2 2 2 Double zinc ribbon zf-C3HC4_4 PF15227.6 KEG10053.1 - 8.1e-05 22.7 12.8 9.3e-05 22.5 8.3 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEG10053.1 - 0.00016 21.4 8.1 0.00016 21.4 8.1 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEG10053.1 - 0.00022 21.0 8.6 0.00022 21.0 8.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KEG10053.1 - 0.0006 19.6 3.2 0.0011 18.8 3.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KEG10053.1 - 0.039 14.1 5.6 0.039 14.1 5.6 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KEG10053.1 - 0.054 13.3 7.4 0.054 13.3 7.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger DUF1272 PF06906.11 KEG10053.1 - 0.23 11.6 12.8 0.12 12.5 10.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) TerY_C PF15616.6 KEG10053.1 - 1.2 9.3 10.1 0.12 12.5 4.4 2.0 2 1 1 3 3 3 0 TerY-C metal binding domain DUF2189 PF09955.9 KEG10054.1 - 0.019 15.2 0.5 0.031 14.5 0.5 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) SURF1 PF02104.15 KEG10055.1 - 1.3e-28 100.5 0.1 1.3e-28 100.5 0.1 2.0 2 1 0 2 2 2 1 SURF1 family LapA_dom PF06305.11 KEG10055.1 - 1.1 9.2 3.2 5.3 6.9 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ATG16 PF08614.11 KEG10056.1 - 0.0011 19.3 1.2 0.0013 19.0 1.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) F_actin_bind PF08919.10 KEG10056.1 - 0.0067 16.5 0.8 0.11 12.6 0.0 2.3 2 1 0 2 2 2 1 F-actin binding KASH_CCD PF14662.6 KEG10056.1 - 0.015 15.1 3.9 0.067 13.0 0.8 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Herpes_BLRF2 PF05812.12 KEG10056.1 - 0.021 15.0 0.2 0.026 14.6 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TMF_DNA_bd PF12329.8 KEG10056.1 - 0.034 14.1 4.8 0.49 10.4 2.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KEG10056.1 - 0.038 13.1 1.2 0.044 12.9 1.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEG10056.1 - 0.071 12.0 2.7 0.086 11.7 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 KEG10056.1 - 0.074 13.1 7.6 3.8 7.7 4.0 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Translin PF01997.16 KEG10056.1 - 0.077 13.0 0.6 0.1 12.6 0.6 1.4 1 1 0 1 1 1 0 Translin family Seadorna_VP6 PF07407.11 KEG10056.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein ZapB PF06005.12 KEG10056.1 - 0.12 12.8 9.1 0.39 11.2 6.0 2.1 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 KEG10056.1 - 0.13 12.4 7.3 0.11 12.6 2.3 2.3 2 1 0 2 2 2 0 bZIP transcription factor NRBF2 PF08961.10 KEG10056.1 - 0.13 11.8 2.1 0.14 11.8 1.0 1.5 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Fungal_TACC PF12709.7 KEG10056.1 - 0.15 12.5 1.1 0.15 12.5 1.1 1.8 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins CCDC92 PF14916.6 KEG10056.1 - 0.16 11.8 5.0 1.7 8.5 0.0 2.9 2 1 0 2 2 2 0 Coiled-coil domain of unknown function YabA PF06156.13 KEG10056.1 - 0.16 12.6 4.2 0.35 11.5 1.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 KEG10056.1 - 0.6 10.5 6.7 0.18 12.2 1.3 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family PikAIV_N PF18605.1 KEG10056.1 - 0.82 9.3 8.1 1.1 8.9 5.7 2.3 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DivIC PF04977.15 KEG10056.1 - 1.1 9.0 5.4 1.5 8.7 3.5 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF2381 PF09544.10 KEG10056.1 - 5.3 6.5 7.2 1.4 8.4 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) Kinesin PF00225.23 KEG10057.1 - 3.7e-84 282.5 0.0 4.6e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain zf-TRAF PF02176.18 KEG10057.1 - 3.5e-15 56.4 45.4 1.4e-07 32.1 6.1 5.3 3 1 2 5 5 5 4 TRAF-type zinc finger Microtub_bd PF16796.5 KEG10057.1 - 3.7e-12 46.4 0.0 6.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding zf-ACC PF17848.1 KEG10057.1 - 9e-05 22.5 16.3 0.58 10.3 4.8 4.6 3 0 0 3 3 3 3 Acetyl-coA carboxylase zinc finger domain zf-Di19 PF05605.12 KEG10057.1 - 0.00025 21.2 30.6 0.0085 16.4 7.6 4.9 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding PhoH PF02562.16 KEG10057.1 - 0.017 14.6 0.4 0.054 12.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KEG10057.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 KEG10057.1 - 0.75 10.6 0.1 0.75 10.6 0.1 4.0 4 0 0 4 4 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain MRPL52 PF18699.1 KEG10058.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Utp13 PF08625.11 KEG10059.1 - 0.026 14.4 0.4 0.39 10.6 0.0 3.0 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain Peptidase_C2 PF00648.21 KEG10060.1 - 2.5e-33 115.4 0.0 5.4e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KEG10060.1 - 2.4e-09 37.6 0.2 6.4e-07 29.7 0.0 3.6 3 1 0 3 3 3 1 Calpain large subunit, domain III TPR_12 PF13424.6 KEG10060.1 - 0.021 15.1 0.0 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG10060.1 - 0.021 14.8 0.1 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10060.1 - 0.024 14.7 0.1 0.88 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2076 PF09849.9 KEG10060.1 - 0.053 13.6 3.3 0.083 12.9 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_1 PF00515.28 KEG10060.1 - 0.21 11.5 0.1 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KEG10060.1 - 0.21 11.7 0.1 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PhyH PF05721.13 KEG10061.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) UAA PF08449.11 KEG10063.1 - 1.4e-31 109.9 10.1 3.5e-31 108.5 6.8 2.7 2 1 0 2 2 2 1 UAA transporter family Renin_r PF07850.14 KEG10063.1 - 0.014 16.0 0.0 0.039 14.6 0.0 1.7 1 0 0 1 1 1 0 Renin receptor-like protein DUF3464 PF11947.8 KEG10063.1 - 0.21 11.4 1.0 0.56 10.0 1.0 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EamA PF00892.20 KEG10063.1 - 9 6.5 20.6 18 5.5 12.0 3.1 2 1 0 2 2 2 0 EamA-like transporter family zf-HC3 PF16827.5 KEG10064.1 - 0.01 16.0 1.0 0.01 16.0 1.0 2.4 2 0 0 2 2 2 0 zinc-finger RL PF17797.1 KEG10064.1 - 0.056 13.4 0.0 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 RL domain SR-25 PF10500.9 KEG10064.1 - 0.19 11.3 11.3 0.28 10.7 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KEG10064.1 - 4.9 6.8 7.2 8.3 6.0 7.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Kelch_4 PF13418.6 KEG10065.1 - 4.3e-24 84.3 9.0 4.8e-06 26.5 0.2 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG10065.1 - 3.1e-22 78.1 5.2 1.4e-05 24.9 0.0 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KEG10065.1 - 3.7e-18 65.1 7.0 0.0025 18.0 0.2 6.8 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KEG10065.1 - 5.3e-16 57.9 11.4 0.00015 21.6 0.2 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KEG10065.1 - 6.2e-15 55.1 15.8 9.8e-05 22.5 0.1 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG10065.1 - 7.4e-14 51.1 16.2 2.6e-05 23.7 0.1 6.3 7 0 0 7 7 7 3 Kelch motif BTB PF00651.31 KEG10065.1 - 1.3e-08 35.1 0.0 3.4e-05 24.0 0.0 3.2 2 2 0 2 2 2 2 BTB/POZ domain ACR_tran PF00873.19 KEG10066.1 - 0.55 7.8 0.7 0.77 7.3 0.7 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MFS_1 PF07690.16 KEG10067.1 - 3.7e-32 111.6 56.9 1.3e-28 100.0 31.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG10067.1 - 5.1e-18 65.2 21.5 7.6e-18 64.6 21.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KEG10067.1 - 6.7e-14 51.1 19.7 2.4e-09 36.0 9.6 3.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KEG10067.1 - 1.7e-06 27.6 0.6 1.7e-06 27.6 0.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KEG10067.1 - 3.8e-05 22.7 17.5 0.00053 19.0 6.2 2.1 1 1 1 2 2 2 2 MFS_1 like family CybS PF05328.12 KEG10067.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit DUF2929 PF11151.8 KEG10067.1 - 5.7 7.3 8.7 1.7 9.0 3.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) FtsJ PF01728.19 KEG10071.1 - 9.1e-40 136.6 0.4 1.2e-39 136.2 0.4 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 KEG10072.1 - 4.4e-05 23.0 0.0 7.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FAM217 PF15344.6 KEG10073.1 - 5.5e-05 23.2 3.2 5.5e-05 23.2 3.2 3.1 3 1 0 3 3 3 1 FAM217 family Med26_C PF15693.5 KEG10073.1 - 0.078 13.1 1.9 0.19 11.8 1.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 26 C-terminal C2 PF00168.30 KEG10074.1 - 1.4e-25 89.5 0.1 2e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 C2 domain PQQ_2 PF13360.6 KEG10077.1 - 0.00075 19.1 0.6 0.0054 16.3 0.6 2.3 2 1 0 2 2 2 1 PQQ-like domain Myc_N PF01056.18 KEG10077.1 - 0.0069 16.3 2.9 0.013 15.5 2.9 1.3 1 0 0 1 1 1 1 Myc amino-terminal region OMS28_porin PF03532.13 KEG10077.1 - 0.44 9.7 1.6 0.82 8.9 1.6 1.3 1 0 0 1 1 1 0 OMS28 porin WRNPLPNID PF15017.6 KEG10077.1 - 1.3 10.0 4.6 2.9 8.9 4.6 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Pribosyltran_N PF13793.6 KEG10078.1 - 9.5e-37 125.5 0.1 1.8e-34 118.2 0.1 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEG10078.1 - 8.2e-22 78.1 0.2 1e-20 74.6 0.1 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEG10078.1 - 1.1e-15 57.5 0.0 2.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1126 PF06565.12 KEG10079.1 - 2.2e-74 246.0 0.3 2e-26 91.8 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_6 PF13405.6 KEG10079.1 - 1.5e-07 30.8 0.2 0.00017 21.2 0.3 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KEG10079.1 - 2.7e-06 26.5 0.1 0.00013 21.2 0.5 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KEG10079.1 - 0.00047 20.5 0.3 0.0037 17.7 0.5 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KEG10079.1 - 0.0013 18.6 0.1 0.056 13.3 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KEG10079.1 - 0.0027 17.1 0.3 0.0071 15.8 0.3 1.7 1 0 0 1 1 1 1 EF hand TPR_1 PF00515.28 KEG10080.1 - 1.6e-44 147.9 43.1 4.3e-08 32.7 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10080.1 - 1.8e-39 130.7 47.3 5e-05 23.1 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KEG10080.1 - 1.2e-30 105.2 0.9 9e-15 54.4 0.5 3.4 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 KEG10080.1 - 1.4e-28 98.3 29.1 2.1e-07 30.5 0.2 8.5 5 3 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 KEG10080.1 - 1e-20 72.1 36.3 0.00013 21.9 0.3 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 KEG10080.1 - 2.1e-17 63.5 20.6 1.3e-05 25.7 0.4 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEG10080.1 - 3.1e-16 58.7 24.3 0.069 14.0 0.1 9.6 3 3 7 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEG10080.1 - 4.7e-16 58.9 36.7 1.6e-06 28.3 1.2 7.3 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEG10080.1 - 5.3e-16 58.9 17.6 0.0017 18.8 0.2 6.7 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEG10080.1 - 3.8e-10 39.1 21.1 0.4 10.8 0.0 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEG10080.1 - 3.2e-09 36.8 10.4 4.5e-05 23.5 0.1 5.5 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEG10080.1 - 6.3e-09 35.4 31.2 0.00066 19.5 0.4 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG10080.1 - 1.2e-07 31.6 25.9 0.016 15.5 0.2 7.7 9 1 1 10 10 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG10080.1 - 8e-05 22.6 17.8 0.063 13.4 0.2 7.5 8 0 0 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KEG10080.1 - 0.00014 22.0 33.9 0.1 12.8 7.8 5.9 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KEG10080.1 - 0.00026 21.4 24.1 2.9 8.7 0.1 8.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 KEG10080.1 - 0.00033 20.4 24.1 0.041 13.6 0.9 4.9 3 3 2 5 5 5 3 Tetratricopeptide repeat-like domain DnaI_N PF07319.11 KEG10080.1 - 0.032 14.9 0.2 1.5 9.6 0.0 3.2 3 0 0 3 3 2 0 Primosomal protein DnaI N-terminus TPR_3 PF07720.12 KEG10080.1 - 0.034 14.1 13.0 6.5 6.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KEG10080.1 - 0.038 14.1 17.0 2.3 8.3 0.6 5.6 4 3 0 5 5 4 0 Domain of Unknown Function (DUF3856) Ykof PF07615.11 KEG10080.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 YKOF-related Family MIT PF04212.18 KEG10080.1 - 0.18 11.9 27.0 0.58 10.3 0.1 7.6 7 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 KEG10080.1 - 0.24 11.7 11.7 1.3 9.4 0.4 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 KEG10080.1 - 0.77 10.0 4.0 3 8.1 0.0 3.4 4 0 0 4 4 2 0 Tetratrico peptide repeat BTAD PF03704.17 KEG10080.1 - 0.88 10.0 18.5 2.9 8.3 3.7 4.9 2 2 2 4 4 4 0 Bacterial transcriptional activator domain CdiI_2 PF18593.1 KEG10081.1 - 0.076 13.7 0.7 4.2 8.1 0.0 3.3 3 0 0 3 3 3 0 CdiI immunity protein Muted PF14942.6 KEG10081.1 - 7.5 6.9 13.0 0.2 12.0 0.4 3.1 3 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein tRNA-synt_2d PF01409.20 KEG10083.1 - 7.6e-82 274.5 0.2 1.1e-81 273.9 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 KEG10083.1 - 1e-12 47.6 0.0 1.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 KEG10083.1 - 6.1e-08 32.8 0.1 1.6e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 KEG10083.1 - 0.00073 18.7 1.0 0.0031 16.6 0.3 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KEG10083.1 - 0.0031 17.5 0.1 0.013 15.4 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_synthFbeta PF17759.1 KEG10083.1 - 0.033 13.6 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain MarR_2 PF12802.7 KEG10083.1 - 0.034 14.0 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 MarR family DprA_WH PF17782.1 KEG10083.1 - 0.052 13.7 0.2 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 DprA winged helix domain MarR PF01047.22 KEG10083.1 - 0.087 12.8 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 KEG10083.1 - 0.14 12.1 0.0 25 4.9 0.0 2.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB RasGAP PF00616.19 KEG10084.1 - 9.6e-12 45.0 0.0 4.3e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF4106 PF13388.6 KEG10085.1 - 0.075 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TAP_C PF03943.13 KEG10085.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain RRM_1 PF00076.22 KEG10086.1 - 6.6e-17 61.1 0.0 0.00094 19.0 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG10086.1 - 2.5e-10 40.0 0.0 1.5e-08 34.3 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KEG10086.1 - 3.4e-05 24.0 0.2 0.00025 21.2 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 KEG10086.1 - 0.097 12.5 0.1 1 9.3 0.1 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KEG10087.1 - 1.4e-10 40.8 1.6 8.4e-06 25.4 0.3 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KEG10087.1 - 2.1e-06 27.5 0.0 0.086 12.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KEG10087.1 - 7.5e-05 22.9 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 RRM-like domain Cyclin PF08613.11 KEG10088.1 - 1.1e-27 97.4 0.2 1.5e-27 96.9 0.2 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEG10088.1 - 1.3e-10 41.1 0.1 4.4e-10 39.4 0.1 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain HSP70 PF00012.20 KEG10091.1 - 9.8e-40 136.3 14.9 1.4e-38 132.5 0.0 3.7 3 1 1 4 4 4 2 Hsp70 protein LAP1C PF05609.12 KEG10091.1 - 0.99 8.4 13.0 2 7.4 13.0 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) COPI_C PF06957.11 KEG10091.1 - 2.7 6.7 12.1 5.5 5.6 12.1 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Myc_N PF01056.18 KEG10091.1 - 4 7.2 10.4 2.3 8.0 7.1 2.0 2 0 0 2 2 2 0 Myc amino-terminal region NST1 PF13945.6 KEG10091.1 - 4.4 7.4 15.9 0.12 12.5 9.4 1.6 2 0 0 2 2 2 0 Salt tolerance down-regulator Peptidase_M16 PF00675.20 KEG10092.1 - 1.3e-42 145.3 0.4 4.7e-42 143.5 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEG10092.1 - 1.4e-21 77.3 0.0 9.5e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain ORC2 PF04084.14 KEG10093.1 - 9.1e-05 21.5 0.0 0.069 12.0 0.0 2.2 2 0 0 2 2 2 2 Origin recognition complex subunit 2 ADH_zinc_N PF00107.26 KEG10095.1 - 3.8e-15 56.0 0.0 6.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEG10095.1 - 1.9e-11 45.1 0.0 3.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEG10095.1 - 1.3e-10 41.1 0.0 5.2e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEG10095.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase LRR_6 PF13516.6 KEG10096.1 - 1.6e-49 161.8 54.5 0.00038 20.3 0.5 20.0 20 0 0 20 20 20 15 Leucine Rich repeat LRR_4 PF12799.7 KEG10096.1 - 5.5e-10 39.3 42.5 0.062 13.8 0.1 13.8 12 4 3 15 15 15 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10096.1 - 0.00029 20.6 45.1 5 7.0 0.1 13.1 10 6 2 13 13 13 6 Leucine rich repeat LRR_1 PF00560.33 KEG10096.1 - 0.0013 19.0 29.5 55 4.9 0.3 13.6 16 0 0 16 16 16 0 Leucine Rich Repeat XPC-binding PF09280.11 KEG10096.1 - 0.0025 17.5 1.2 13 5.6 0.1 4.2 4 0 0 4 4 4 1 XPC-binding domain T2SSI PF02501.17 KEG10097.1 - 0.026 14.7 3.6 0.71 10.1 0.1 3.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein I WD40 PF00400.32 KEG10098.1 - 5.1e-05 24.0 12.2 0.065 14.1 0.0 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG10098.1 - 0.025 15.1 0.7 1.1 9.8 0.1 3.2 3 0 0 3 3 3 0 PQQ-like domain Pkinase PF00069.25 KEG10099.1 - 6.3e-45 153.6 0.0 8.5e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10099.1 - 1.9e-15 56.8 0.0 2.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG10099.1 - 0.00091 19.2 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG10099.1 - 0.0051 16.2 0.1 0.0093 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG10099.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HECT PF00632.25 KEG10101.1 - 5.4e-41 141.1 0.0 9.6e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KEG10101.1 - 1.4e-05 25.2 0.0 0.0023 18.0 0.1 3.3 3 0 0 3 3 3 1 SPRY domain Neuralized PF07177.12 KEG10101.1 - 0.047 13.7 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 Neuralized ParA PF10609.9 KEG10104.1 - 1.2e-90 303.2 0.0 1.4e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEG10104.1 - 4.6e-13 49.3 0.0 1.6e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEG10104.1 - 1.4e-09 38.1 0.7 2.2e-07 31.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KEG10104.1 - 9.4e-08 31.6 1.4 5e-07 29.3 1.4 1.9 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KEG10104.1 - 0.00011 21.7 0.0 0.0022 17.5 0.2 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KEG10104.1 - 0.00016 21.0 2.5 0.00034 19.9 0.6 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 KEG10104.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 KEG10104.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ VCBS PF13517.6 KEG10105.1 - 8.8e-14 51.8 3.2 0.1 13.2 0.0 5.5 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KEG10105.1 - 2.1e-05 24.5 12.1 0.056 13.6 0.3 4.8 4 0 0 4 4 4 3 FG-GAP repeat EF-hand_5 PF13202.6 KEG10105.1 - 0.0061 16.0 4.6 6.1 6.5 0.2 3.7 3 0 0 3 3 3 2 EF hand TcdB_toxin_midN PF12256.8 KEG10105.1 - 0.0098 15.3 0.2 2.2 7.6 0.0 3.3 3 0 0 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.32 KEG10105.1 - 0.19 11.4 3.9 22 4.9 0.1 3.5 3 0 0 3 3 3 0 EF hand DUF676 PF05057.14 KEG10106.1 - 7.9e-13 48.4 0.0 1.7e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KEG10106.1 - 0.0097 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KEG10106.1 - 0.036 13.3 0.1 0.091 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 KEG10106.1 - 0.042 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 KEG10106.1 - 0.072 12.9 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Palmitoyl protein thioesterase DUF3446 PF11928.8 KEG10106.1 - 5.1 7.5 12.9 59 4.1 10.8 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Hexapep PF00132.24 KEG10107.1 - 1.5e-06 27.7 8.2 3.7e-05 23.3 3.6 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KEG10107.1 - 2.8e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEG10107.1 - 0.0019 18.6 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KEG10107.1 - 0.0067 15.4 0.4 0.011 14.7 0.4 1.3 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KEG10107.1 - 0.028 12.6 1.7 0.19 9.8 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KEG10107.1 - 0.04 13.7 9.3 0.025 14.4 4.1 2.7 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF1093 PF06486.11 KEG10107.1 - 0.18 12.5 0.3 0.32 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) ATP-synt_ab PF00006.25 KEG10108.1 - 1.9e-68 230.3 0.0 2.5e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEG10108.1 - 7.4e-13 48.8 0.5 1.6e-12 47.8 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_transf_25 PF01755.17 KEG10109.1 - 1.9e-10 41.0 0.0 9.8e-07 28.8 0.0 2.1 1 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) PUMA PF15826.5 KEG10109.1 - 0.38 10.9 2.4 39 4.3 0.0 3.0 2 1 1 3 3 3 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Snf7 PF03357.21 KEG10110.1 - 9.2e-27 93.7 28.4 1.1e-26 93.5 28.1 1.3 1 1 0 1 1 1 1 Snf7 DUF768 PF05589.11 KEG10110.1 - 0.065 13.2 0.9 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF768) DUF1699 PF08004.11 KEG10110.1 - 0.16 11.6 8.1 0.13 11.9 1.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1699) LMBR1 PF04791.16 KEG10110.1 - 3.5 6.4 9.3 4.1 6.2 9.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CRAL_TRIO PF00650.20 KEG10111.1 - 6.6e-26 90.9 0.0 1.2e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KEG10111.1 - 0.053 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Vps26 PF03643.15 KEG10112.1 - 1.2e-59 201.6 0.1 1.5e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KEG10112.1 - 4.4e-05 23.6 0.5 0.071 13.2 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.25 KEG10113.1 - 1.6e-38 132.1 0.0 2.2e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG10113.1 - 1.2e-15 57.7 0.0 1.7e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG10113.1 - 2.3e-12 47.2 0.7 1.3e-11 44.8 0.7 2.1 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.27 KEG10113.1 - 5.1e-05 23.8 0.3 0.0001 22.7 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEG10113.1 - 0.0014 18.0 0.5 0.0029 16.9 0.3 1.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEG10113.1 - 0.003 17.5 0.1 0.0045 16.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KEG10113.1 - 0.0056 15.9 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 KEG10113.1 - 0.042 13.1 0.6 0.067 12.4 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Epimerase PF01370.21 KEG10113.1 - 0.051 13.0 0.2 0.16 11.4 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KEG10113.1 - 0.062 12.7 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KEG10113.1 - 0.063 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KEG10113.1 - 0.21 10.7 0.9 0.3 10.1 0.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribosomal_L29e PF01779.17 KEG10114.1 - 3.1e-14 53.0 5.0 3.1e-14 53.0 5.0 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_L29e PF01779.17 KEG10115.1 - 3.1e-14 53.0 5.0 3.1e-14 53.0 5.0 1.6 2 0 0 2 2 2 1 Ribosomal L29e protein family ZapB PF06005.12 KEG10118.1 - 0.082 13.4 1.0 0.19 12.2 1.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapB BPL_LplA_LipB PF03099.19 KEG10119.1 - 1.1e-13 51.2 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HBS1_N PF08938.10 KEG10120.1 - 0.024 14.9 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 HBS1 N-terminus Bromodomain PF00439.25 KEG10121.1 - 2.9e-15 56.1 0.0 6.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain HSCB_C PF07743.13 KEG10121.1 - 0.095 13.2 0.7 0.38 11.3 0.2 2.2 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF4777 PF16007.5 KEG10121.1 - 0.16 12.2 0.1 0.81 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) RRM_1 PF00076.22 KEG10123.1 - 4.2e-14 52.1 0.1 1e-06 28.5 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.6 KEG10123.1 - 0.001 18.8 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) DUF853 PF05872.12 KEG10123.1 - 0.0088 14.7 0.3 0.011 14.4 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) RRM_3 PF08777.11 KEG10123.1 - 0.01 15.9 0.9 0.076 13.1 1.0 2.2 2 1 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 KEG10123.1 - 0.044 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DNA_ligase_IV PF11411.8 KEG10123.1 - 0.1 12.8 0.1 5 7.3 0.0 2.6 2 0 0 2 2 2 0 DNA ligase IV Neur_chan_memb PF02932.16 KEG10123.1 - 0.38 10.8 0.7 0.42 10.6 0.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_transf_22 PF03901.17 KEG10124.1 - 3.6e-26 92.3 19.2 5.7e-26 91.7 19.2 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Mid2 PF04478.12 KEG10124.1 - 0.24 11.2 3.0 0.38 10.6 1.4 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2733 PF10813.8 KEG10124.1 - 0.33 10.8 1.0 3.2 7.6 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) SR-25 PF10500.9 KEG10124.1 - 3.8 7.1 13.6 6.6 6.3 13.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L11_N PF03946.14 KEG10125.1 - 1.4e-14 53.7 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KEG10125.1 - 1.5e-10 41.5 0.0 3.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Lipase_GDSL_2 PF13472.6 KEG10127.1 - 3.2e-21 76.5 0.1 6.4e-21 75.5 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEG10127.1 - 5e-13 49.5 0.0 1e-12 48.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DZR PF12773.7 KEG10128.1 - 4.6e-07 29.8 69.7 0.00017 21.5 6.4 7.2 5 2 2 7 7 7 5 Double zinc ribbon zf-ribbon_3 PF13248.6 KEG10128.1 - 0.0047 16.3 1.2 0.0047 16.3 1.2 10.2 9 2 1 10 10 10 5 zinc-ribbon domain TrmB PF01978.19 KEG10128.1 - 0.068 13.1 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Speriolin_N PF15058.6 KEG10129.1 - 0.021 14.9 1.4 0.021 14.9 1.4 1.2 1 0 0 1 1 1 0 Speriolin N terminus Atg14 PF10186.9 KEG10130.1 - 7.7e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 OstA PF03968.14 KEG10130.1 - 0.018 15.2 0.9 0.036 14.3 0.9 1.4 1 0 0 1 1 1 0 OstA-like protein FANCA_interact PF15751.5 KEG10130.1 - 0.11 13.0 0.4 0.36 11.3 0.4 1.8 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain Spc7 PF08317.11 KEG10130.1 - 0.43 9.4 9.9 0.62 8.9 9.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EMG1 PF03587.14 KEG10131.1 - 0.0017 18.0 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Peptidase_M22 PF00814.25 KEG10133.1 - 2.8e-85 286.3 0.0 3.5e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family VCBS PF13517.6 KEG10136.1 - 6.2e-14 52.3 14.9 3.3e-05 24.4 4.6 6.3 4 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KEG10136.1 - 0.00016 21.7 22.5 0.12 12.5 1.8 6.3 6 0 0 6 6 6 4 FG-GAP repeat PQQ PF01011.21 KEG10136.1 - 0.0046 16.8 0.4 41 4.4 0.0 4.6 4 0 0 4 4 4 1 PQQ enzyme repeat TcdB_toxin_midN PF12256.8 KEG10136.1 - 0.02 14.3 3.0 6 6.2 0.1 4.1 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region Dus PF01207.17 KEG10137.1 - 1.4e-49 168.9 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) BT1 PF03092.16 KEG10138.1 - 2.2e-183 610.3 10.3 2.5e-183 610.1 10.3 1.0 1 0 0 1 1 1 1 BT1 family DUF3147 PF11345.8 KEG10138.1 - 0.4 11.1 10.4 0.29 11.5 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) dCMP_cyt_deam_1 PF00383.23 KEG10139.1 - 1.5e-11 44.0 2.9 2.5e-11 43.3 2.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KEG10139.1 - 8.8e-08 32.4 0.6 1.2e-06 28.8 0.5 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region QVR PF17064.5 KEG10140.1 - 0.19 12.0 0.6 0.38 11.0 0.6 1.4 1 0 0 1 1 1 0 Sleepless protein Acetyltransf_9 PF13527.7 KEG10141.1 - 0.045 13.8 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WEMBL PF05701.11 KEG10141.1 - 0.06 12.0 2.4 0.072 11.8 2.4 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Piezo_RRas_bdg PF12166.8 KEG10142.1 - 1.5e-30 106.8 0.1 1.8e-30 106.6 0.1 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain BTB PF00651.31 KEG10142.1 - 0.037 14.2 0.2 0.078 13.2 0.2 1.6 1 1 0 1 1 1 0 BTB/POZ domain HCV_NS2 PF01538.18 KEG10142.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DNA_pol_A PF00476.20 KEG10143.1 - 1.6e-94 317.0 0.0 2.4e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A HupE_UreJ_2 PF13795.6 KEG10143.1 - 0.092 12.4 0.5 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 HupE / UreJ protein CCSAP PF15748.5 KEG10143.1 - 1.1 9.4 15.1 1.7 8.7 15.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spt20 PF12090.8 KEG10143.1 - 1.6 8.3 5.8 2.6 7.6 5.8 1.3 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 KEG10143.1 - 4.7 7.1 17.6 6.6 6.6 17.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DnaJ PF00226.31 KEG10146.1 - 6.8e-13 48.5 0.1 1.5e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Orexin PF02072.15 KEG10146.1 - 0.055 13.4 1.7 0.079 12.9 0.2 1.9 1 1 1 2 2 2 0 Prepro-orexin DUF5553 PF17707.1 KEG10146.1 - 0.057 12.9 4.4 0.099 12.1 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5553) ADIP PF11559.8 KEG10147.1 - 4.9e-05 23.5 5.6 0.0027 17.8 1.3 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DASH_Spc19 PF08287.11 KEG10147.1 - 0.00029 20.8 3.9 0.00052 19.9 3.9 1.5 1 0 0 1 1 1 1 Spc19 ZapB PF06005.12 KEG10147.1 - 0.004 17.6 9.7 0.79 10.2 0.1 2.3 2 0 0 2 2 2 2 Cell division protein ZapB APG6_N PF17675.1 KEG10147.1 - 0.021 15.3 13.2 0.072 13.6 2.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KEG10147.1 - 0.028 14.7 9.5 0.35 11.1 1.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KEG10147.1 - 0.028 14.4 10.5 0.13 12.3 1.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KEG10147.1 - 0.041 14.1 7.7 0.17 12.1 1.4 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.6 KEG10147.1 - 0.041 13.6 7.8 0.42 10.3 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 KEG10147.1 - 0.055 13.6 0.7 0.055 13.6 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus EzrA PF06160.12 KEG10147.1 - 0.072 11.2 5.2 0.02 13.1 1.2 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Med9 PF07544.13 KEG10147.1 - 0.08 13.0 0.4 0.08 13.0 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fez1 PF06818.15 KEG10147.1 - 0.11 12.9 7.1 0.17 12.3 6.9 1.4 1 1 0 1 1 1 0 Fez1 FlgN PF05130.12 KEG10147.1 - 0.12 12.8 8.5 0.18 12.3 8.5 1.3 1 0 0 1 1 1 0 FlgN protein Prefoldin_2 PF01920.20 KEG10147.1 - 0.16 12.0 8.3 0.47 10.4 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.17 KEG10147.1 - 0.2 11.6 6.8 2.9 7.8 0.4 2.4 2 1 0 2 2 2 0 Prefoldin subunit Exonuc_VII_L PF02601.15 KEG10147.1 - 0.28 10.7 1.7 0.39 10.2 1.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_C PF15908.5 KEG10147.1 - 0.39 11.0 4.2 0.12 12.7 0.5 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Snapin_Pallidin PF14712.6 KEG10147.1 - 0.39 11.2 5.5 2.9 8.4 0.1 2.8 2 1 1 3 3 3 0 Snapin/Pallidin SKA1 PF07160.12 KEG10147.1 - 0.55 10.0 4.0 0.93 9.3 3.3 1.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 CCDC53 PF10152.9 KEG10147.1 - 0.66 10.4 6.9 6.4 7.2 6.9 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1664 PF07889.12 KEG10147.1 - 0.73 9.9 3.2 3.7 7.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KEG10147.1 - 1.6 8.8 11.9 1.2 9.2 1.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MPS2 PF17060.5 KEG10147.1 - 1.8 7.8 4.4 3.8 6.7 4.4 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF4200 PF13863.6 KEG10147.1 - 3.1 8.2 10.0 11 6.5 1.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 KEG10148.1 - 0.14 12.3 2.3 7.6 6.7 0.1 3.0 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KEG10148.1 - 0.23 11.8 8.0 6.7 7.1 0.1 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF1640 PF07798.11 KEG10148.1 - 0.94 9.5 8.3 0.082 13.0 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) bZIP_2 PF07716.15 KEG10148.1 - 4.7 7.4 15.6 11 6.1 0.2 3.8 3 0 0 3 3 3 0 Basic region leucine zipper Exo_endo_phos PF03372.23 KEG10149.1 - 7.9e-06 25.6 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DnaJ PF00226.31 KEG10150.1 - 4.3e-09 36.4 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4461 PF14688.6 KEG10150.1 - 0.0081 16.0 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) WASH-7_mid PF14744.6 KEG10151.1 - 7e-146 485.8 0.3 1.1e-145 485.1 0.3 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.6 KEG10151.1 - 4.5e-69 233.5 0.1 1e-68 232.3 0.0 1.6 2 0 0 2 2 2 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 KEG10151.1 - 1.4e-57 194.2 0.4 3.5e-57 192.9 0.4 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal TetR_C_27 PF17935.1 KEG10151.1 - 0.029 14.4 0.6 2.6 8.2 0.1 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Serine_rich PF08824.10 KEG10151.1 - 0.071 13.1 0.7 0.51 10.3 0.1 2.6 2 0 0 2 2 2 0 Serine rich protein interaction domain Sigma70_ner PF04546.13 KEG10151.1 - 5 7.0 9.0 0.2 11.5 1.1 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_12 PF13424.6 KEG10152.1 - 6.5e-17 61.6 15.5 1.9e-09 37.7 2.6 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KEG10152.1 - 8.8e-11 41.3 13.0 0.0011 18.8 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10152.1 - 6e-09 35.3 8.6 0.22 11.8 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG10152.1 - 5.6e-06 26.0 3.2 1.1 9.5 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG10152.1 - 9.5e-05 22.1 1.6 1.6 8.7 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEG10152.1 - 0.0005 19.5 1.0 0.0005 19.5 1.0 2.7 3 1 0 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 KEG10152.1 - 0.001 18.8 0.1 0.75 9.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KEG10152.1 - 0.005 17.0 3.4 9.3 6.7 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KEG10152.1 - 0.0052 16.2 1.3 0.85 9.1 0.0 3.6 3 0 0 3 3 3 1 SHNi-TPR TPR_14 PF13428.6 KEG10152.1 - 0.014 16.2 17.8 1.1 10.2 0.0 6.4 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG10152.1 - 0.99 10.0 8.7 5.9 7.5 0.0 4.8 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG10152.1 - 7.4 7.3 16.5 7.9 7.2 1.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10153.1 - 0.00031 20.6 3.5 0.44 10.8 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG10153.1 - 0.0019 18.7 2.6 0.016 15.7 2.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG10153.1 - 0.0076 16.5 3.3 0.58 10.4 0.4 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KEG10153.1 - 0.0094 16.2 9.5 0.25 11.7 2.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG10153.1 - 0.037 14.7 1.0 0.093 13.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4807 PF16065.5 KEG10153.1 - 0.041 13.5 0.2 0.099 12.3 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4807) SPOB_a PF14689.6 KEG10153.1 - 0.12 12.1 0.1 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_14 PF13428.6 KEG10153.1 - 0.4 11.6 7.3 3.3 8.8 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEG10153.1 - 0.77 10.6 0.2 0.77 10.6 0.2 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Fzo_mitofusin PF04799.13 KEG10154.1 - 0.078 12.5 1.0 0.13 11.8 1.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF2312 PF10073.9 KEG10154.1 - 0.082 12.6 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Csm1_N PF18504.1 KEG10154.1 - 2.9 8.3 6.4 2.4 8.6 1.8 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4505 PF14956.6 KEG10155.1 - 1.3e-20 73.9 0.0 5e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Amastin PF07344.11 KEG10156.1 - 4.8e-34 117.4 9.4 6.1e-34 117.1 9.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein ZZ PF00569.17 KEG10156.1 - 0.076 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF5409 PF17421.2 KEG10156.1 - 1.4 9.6 5.2 21 5.9 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5409) GWT1 PF06423.12 KEG10156.1 - 3.3 7.8 7.2 7.6 6.7 7.2 1.7 1 1 0 1 1 1 0 GWT1 FA_desaturase PF00487.24 KEG10156.1 - 5.6 6.7 7.8 0.32 10.8 1.4 1.9 1 1 1 2 2 2 0 Fatty acid desaturase Kinesin PF00225.23 KEG10157.1 - 1.5e-93 313.3 0.5 3e-93 312.4 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG10157.1 - 2.1e-16 60.2 0.0 6.3e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding MAP70 PF07058.11 KEG10157.1 - 0.041 12.6 2.4 0.064 12.0 2.4 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 NINJA_B PF16136.5 KEG10158.1 - 0.032 14.6 4.9 0.072 13.5 4.9 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal K_channel_TID PF07941.11 KEG10158.1 - 0.058 13.9 8.5 0.17 12.3 8.5 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Spc7 PF08317.11 KEG10158.1 - 0.61 8.9 7.3 1 8.1 7.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BSD PF03909.17 KEG10159.1 - 1.1e-06 28.6 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 BSD domain PepSY_2 PF13670.6 KEG10159.1 - 0.15 12.0 4.4 0.42 10.6 4.4 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain PHD_2 PF13831.6 KEG10160.1 - 0.016 14.7 0.7 0.033 13.7 0.7 1.4 1 0 0 1 1 1 0 PHD-finger Thymidylate_kin PF02223.17 KEG10161.1 - 2.9e-17 62.9 0.0 3.5e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 KEG10161.1 - 0.00018 21.7 1.0 0.00077 19.6 1.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG10161.1 - 0.00025 21.6 0.0 0.0011 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG10161.1 - 0.033 14.5 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEG10161.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Glyco_transf_11 PF01531.16 KEG10162.1 - 2.9e-13 49.7 0.4 4.4e-07 29.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 11 O-FucT PF10250.9 KEG10162.1 - 0.098 12.3 0.1 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase Glutaredoxin PF00462.24 KEG10163.1 - 2e-18 66.3 0.1 6.1e-18 64.8 0.1 1.8 2 0 0 2 2 2 1 Glutaredoxin TarH PF02203.15 KEG10164.1 - 0.016 15.2 1.3 0.028 14.4 1.3 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Mito_fiss_reg PF05308.11 KEG10164.1 - 0.68 10.0 10.1 0.055 13.5 5.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator ubiquitin PF00240.23 KEG10166.1 - 3.4e-07 29.9 0.0 6.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KEG10166.1 - 1.1e-06 28.5 0.7 1.1e-06 28.5 0.7 2.2 3 0 0 3 3 3 1 UBA/TS-N domain CUE PF02845.16 KEG10166.1 - 0.023 14.4 0.8 2.1 8.1 0.1 2.8 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.6 KEG10166.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GerD PF17898.1 KEG10166.1 - 0.33 10.9 7.5 0.49 10.4 2.0 2.2 1 1 0 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 KEG10166.1 - 1.1 9.3 17.5 0.59 10.1 3.5 3.0 3 0 0 3 3 3 0 STI1 domain Pkinase PF00069.25 KEG10167.1 - 2.6e-80 269.6 0.0 3e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10167.1 - 5.4e-36 124.2 0.0 1e-35 123.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEG10167.1 - 0.0013 17.7 0.1 0.0071 15.3 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG10167.1 - 0.0014 18.6 0.2 0.0054 16.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG10167.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ING PF12998.7 KEG10168.1 - 0.063 13.9 10.4 0.045 14.3 4.5 2.6 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Pneumo_M2 PF07380.11 KEG10168.1 - 0.17 12.2 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 Pneumovirus M2 protein DUF1192 PF06698.11 KEG10168.1 - 0.22 11.6 14.2 0.56 10.3 0.0 4.5 3 1 0 4 4 4 0 Protein of unknown function (DUF1192) Fez1 PF06818.15 KEG10168.1 - 0.27 11.7 21.9 15 5.9 6.2 2.6 1 1 1 2 2 2 0 Fez1 YABBY PF04690.13 KEG10168.1 - 0.52 10.9 3.5 0.78 10.3 3.0 1.5 1 1 0 1 1 1 0 YABBY protein HAUS-augmin3 PF14932.6 KEG10168.1 - 5 6.6 15.0 0.99 8.9 10.0 2.3 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 KEG10168.1 - 8.7 5.6 14.9 3.8e+02 0.2 14.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 KEG10169.1 - 2e-61 206.9 0.0 3.3e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KEG10169.1 - 1.7e-26 92.1 0.0 5.4e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KEG10169.1 - 2.7e-21 75.4 0.1 6e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KEG10169.1 - 7.3e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KEG10169.1 - 3.8e-07 30.4 0.0 1.4e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KEG10169.1 - 4.8e-05 23.2 0.1 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KEG10169.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEG10169.1 - 0.082 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Lipoprotein_9 PF03180.14 KEG10169.1 - 0.12 11.4 0.1 1 8.4 0.0 2.4 2 0 0 2 2 2 0 NLPA lipoprotein CRAL_TRIO PF00650.20 KEG10170.1 - 7.1e-21 74.6 0.0 9.7e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CAP_GLY PF01302.25 KEG10170.1 - 2.5e-12 46.6 0.1 4.2e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain CRAL_TRIO_2 PF13716.6 KEG10170.1 - 0.0017 18.5 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain IF4E PF01652.18 KEG10171.1 - 1.8e-10 40.9 0.0 2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.19 KEG10172.1 - 2.5e-23 82.0 2.7 5.6e-23 80.8 2.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 KEG10172.1 - 1.2e-07 31.4 2.6 4.2e-07 29.6 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KEG10172.1 - 0.0002 21.1 0.2 0.0081 16.0 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 KEG10172.1 - 0.00099 19.3 0.3 0.0019 18.4 0.3 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TrkA_N PF02254.18 KEG10173.1 - 7.4e-05 23.0 0.1 0.0002 21.6 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KEG10173.1 - 0.00023 21.7 0.0 0.00067 20.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KEG10173.1 - 0.011 16.0 0.3 0.035 14.4 0.3 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KEG10173.1 - 0.11 13.0 0.4 0.27 11.7 0.4 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding ShK PF01549.24 KEG10173.1 - 0.14 12.8 1.5 0.41 11.2 0.3 2.5 2 0 0 2 2 2 0 ShK domain-like CENP-B_dimeris PF09026.10 KEG10173.1 - 0.14 12.5 8.0 0.42 11.0 8.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spt5_N PF11942.8 KEG10173.1 - 7.4 7.6 17.5 0.064 14.2 4.9 3.1 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal G_path_suppress PF15991.5 KEG10174.1 - 0.0039 17.4 1.0 0.0093 16.1 1.0 1.6 1 0 0 1 1 1 1 G-protein pathway suppressor Sec8_exocyst PF04048.14 KEG10174.1 - 0.035 14.0 4.5 11 5.9 0.3 4.4 4 1 1 5 5 5 0 Sec8 exocyst complex component specific domain DUF717 PF05338.12 KEG10174.1 - 0.71 10.0 3.3 0.93 9.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF717) PI3K_P85_iSH2 PF16454.5 KEG10174.1 - 3.1 7.4 10.0 8.5 6.0 2.5 3.0 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 KEG10174.1 - 5.8 7.0 14.2 7.6 6.6 1.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF5401 PF17380.2 KEG10175.1 - 0.033 12.3 0.4 0.055 11.5 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Nup35_RRM_2 PF14605.6 KEG10176.1 - 2e-17 62.9 0.0 4.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif M_domain PF12938.7 KEG10176.1 - 0.071 12.9 3.1 0.77 9.5 0.1 2.5 2 0 0 2 2 2 0 M domain of GW182 zf-RING_UBOX PF13445.6 KEG10177.1 - 3.4e-06 27.0 3.9 1.8e-05 24.7 1.8 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG10177.1 - 0.00086 19.1 3.0 0.00086 19.1 3.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEG10177.1 - 0.0013 18.8 2.7 0.0013 18.8 2.7 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING BRCT_2 PF16589.5 KEG10177.1 - 0.0033 17.8 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_2 PF13923.6 KEG10177.1 - 0.007 16.2 7.4 0.007 16.2 7.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG10177.1 - 0.013 15.9 10.1 0.041 14.2 7.3 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 KEG10177.1 - 0.031 14.2 8.4 0.035 14.0 4.8 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KEG10177.1 - 0.039 13.9 11.0 0.019 14.9 5.7 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 KEG10177.1 - 1.3 9.3 6.7 0.3 11.4 2.3 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain IBR PF01485.21 KEG10177.1 - 1.5 9.1 4.1 1.5 9.1 1.3 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 KEG10177.1 - 2.7 7.9 12.9 1.8 8.5 8.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG10177.1 - 3.9 7.4 12.3 1.8 8.5 6.4 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Hox9_act PF04617.13 KEG10178.1 - 0.046 14.5 0.6 0.05 14.4 0.6 1.1 1 0 0 1 1 1 0 Hox9 activation region Ribosomal_S13_N PF08069.12 KEG10181.1 - 7.9e-26 89.9 0.3 1.8e-25 88.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KEG10181.1 - 1.3e-14 54.1 1.1 2e-14 53.5 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.21 KEG10182.1 - 1.7e-12 47.0 0.0 4.6e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 KEG10182.1 - 0.036 14.1 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Regulated-SNARE-like domain DUF2570 PF10828.8 KEG10182.1 - 0.047 13.5 1.0 0.08 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TFIIS_C PF01096.18 KEG10184.1 - 3.9e-16 58.6 3.1 3.9e-16 58.6 3.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KEG10184.1 - 6.3e-07 29.2 3.0 2e-06 27.6 0.9 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 KEG10184.1 - 6e-06 25.7 1.3 0.0013 18.2 0.9 2.8 3 0 0 3 3 3 1 TFIIB zinc-binding zf-RING_12 PF17976.1 KEG10184.1 - 0.00045 20.4 2.7 0.014 15.7 0.2 2.7 1 1 2 3 3 3 1 RING/Ubox like zinc-binding domain Baculo_LEF5_C PF11792.8 KEG10184.1 - 0.031 14.0 1.8 0.044 13.5 0.0 2.3 2 1 1 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.7 KEG10184.1 - 0.07 13.2 0.3 0.07 13.2 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF3088 PF11287.8 KEG10184.1 - 0.13 12.1 0.1 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3088) zinc_ribbon_10 PF10058.9 KEG10184.1 - 0.17 11.7 5.3 10 5.9 0.1 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 KEG10184.1 - 0.23 11.5 7.1 0.18 11.8 1.0 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KEG10184.1 - 0.61 9.6 0.1 0.61 9.6 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.13 KEG10184.1 - 1.4 9.0 5.8 18 5.4 0.1 3.4 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF1936 PF09151.10 KEG10184.1 - 1.8 8.5 0.1 1.8 8.5 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1936) IBR PF01485.21 KEG10184.1 - 2.7 8.3 7.4 3.1 8.1 0.3 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf_C2H2_10 PF18414.1 KEG10184.1 - 3.9 7.1 5.0 7.6 6.2 0.0 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger OrfB_Zn_ribbon PF07282.11 KEG10184.1 - 4.8 7.2 6.6 7.1 6.6 0.3 2.8 2 1 0 3 3 3 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.6 KEG10184.1 - 7.2 7.1 11.3 4.2 7.8 0.5 3.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.6 KEG10184.1 - 7.4 6.6 9.3 6.3 6.8 4.7 2.9 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KEG10184.1 - 8.6 6.2 11.9 2.7 7.8 1.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 KEG10184.1 - 9.1 6.9 10.7 4.3 7.9 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain CNH PF00780.22 KEG10185.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 CNH domain DUF4217 PF13959.6 KEG10186.1 - 0.022 15.0 0.3 0.06 13.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) NAP PF00956.18 KEG10187.1 - 9.1e-62 208.7 0.0 9.1e-62 208.7 0.0 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) A_deamin PF02137.18 KEG10187.1 - 0.0021 17.6 0.1 1.7 8.0 0.1 2.4 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain Cwf_Cwc_15 PF04889.12 KEG10187.1 - 0.0098 15.6 3.0 0.0098 15.6 3.0 3.0 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein DUF4576 PF15144.6 KEG10187.1 - 0.028 14.3 3.1 0.076 12.9 2.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4576) NOA36 PF06524.12 KEG10187.1 - 0.049 12.9 19.3 0.02 14.2 4.1 2.3 2 0 0 2 2 2 0 NOA36 protein MPP6 PF10175.9 KEG10187.1 - 0.19 12.2 0.3 0.19 12.2 0.3 3.0 3 1 0 3 3 3 0 M-phase phosphoprotein 6 CENP-B_dimeris PF09026.10 KEG10187.1 - 0.73 10.3 31.5 0.87 10.0 8.5 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KEG10187.1 - 1.9 8.3 11.6 0.2 11.4 1.0 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BUD22 PF09073.10 KEG10187.1 - 2.5 7.3 18.7 0.08 12.3 12.5 1.6 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 KEG10187.1 - 5.5 6.3 18.4 0.42 10.0 13.4 1.7 2 0 0 2 2 2 0 SDA1 TT_ORF2 PF02957.15 KEG10188.1 - 0.2 12.6 3.2 0.39 11.6 0.0 2.9 3 0 0 3 3 3 0 TT viral ORF2 CCDC53 PF10152.9 KEG10189.1 - 8.7e-22 78.2 0.0 1.1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex BORCS7 PF16088.5 KEG10189.1 - 0.13 12.5 0.3 0.28 11.4 0.2 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 SlyX PF04102.12 KEG10189.1 - 0.7 10.6 0.0 0.7 10.6 0.0 2.4 4 0 0 4 4 4 0 SlyX Synaptobrevin PF00957.21 KEG10190.1 - 4.2e-29 100.2 0.5 1.9e-28 98.1 0.1 2.0 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 KEG10190.1 - 3.9e-14 52.4 0.3 7.9e-14 51.5 0.2 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain Smg8_Smg9 PF10220.9 KEG10190.1 - 0.00017 20.1 0.2 0.0002 19.9 0.2 1.0 1 0 0 1 1 1 1 Smg8_Smg9 PLU-1 PF08429.11 KEG10190.1 - 0.047 12.9 0.1 0.06 12.5 0.1 1.1 1 0 0 1 1 1 0 PLU-1-like protein Serine_rich PF08824.10 KEG10190.1 - 0.054 13.5 0.1 0.086 12.8 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain RPW8 PF05659.11 KEG10190.1 - 0.11 12.2 0.7 0.27 10.9 0.2 1.8 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RPAP3_C PF13877.6 KEG10194.1 - 1.6e-13 51.0 0.0 4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KEG10194.1 - 2.7e-12 45.9 5.3 0.0097 15.7 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10194.1 - 4.2e-11 42.1 8.4 0.00028 20.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG10194.1 - 4.9e-11 42.1 3.2 1.2e-06 28.1 0.2 3.2 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 KEG10194.1 - 1.7e-06 28.4 3.2 0.034 15.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG10194.1 - 4.5e-06 27.2 15.1 4.7e-05 24.0 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG10194.1 - 6.3e-05 23.0 0.4 6.3e-05 23.0 0.4 4.2 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG10194.1 - 0.00036 20.5 5.3 1.1 9.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG10194.1 - 0.0038 17.4 0.4 0.014 15.6 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KEG10194.1 - 0.0039 17.7 5.4 0.19 12.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 KEG10194.1 - 0.0086 14.9 0.1 0.0086 14.9 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_3 PF07720.12 KEG10194.1 - 0.018 15.0 0.1 0.068 13.2 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG10194.1 - 0.03 15.0 4.2 0.6 10.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt5_N PF11942.8 KEG10194.1 - 0.031 15.3 11.6 0.031 15.3 11.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TPR_12 PF13424.6 KEG10194.1 - 0.043 14.1 0.6 0.043 14.1 0.6 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG10194.1 - 0.2 11.7 1.5 12 6.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG10194.1 - 0.29 11.6 2.8 19 5.9 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat CDC45 PF02724.14 KEG10194.1 - 6.6 4.9 14.5 1.3 7.2 11.2 1.4 2 0 0 2 2 2 0 CDC45-like protein DnaJ_C PF01556.18 KEG10195.1 - 1.7e-34 119.0 0.1 2.2e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG10195.1 - 4.2e-27 94.0 0.7 6.6e-27 93.4 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEG10195.1 - 1.3e-14 54.2 15.1 2.3e-14 53.5 15.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEG10195.1 - 0.0038 17.1 11.3 0.13 12.2 1.6 2.9 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KEG10195.1 - 0.01 15.9 4.8 1.2 9.2 0.8 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RseC_MucC PF04246.12 KEG10195.1 - 0.76 9.7 6.8 0.83 9.6 1.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DZR PF12773.7 KEG10195.1 - 1.9 8.6 9.8 22 5.2 9.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Aldo_ket_red PF00248.21 KEG10196.1 - 1.2e-39 136.3 0.0 1.8e-39 135.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.13 KEG10197.1 - 6e-09 35.7 0.2 1.8e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 KEG10197.1 - 0.002 18.4 0.8 0.018 15.4 0.1 2.4 2 1 1 3 3 3 1 Penicillinase repressor UDPG_MGDP_dh PF00984.19 KEG10197.1 - 0.069 13.4 0.0 0.93 9.7 0.0 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Swi5 PF07061.11 KEG10197.1 - 0.099 12.7 1.6 1.8 8.7 0.0 2.6 1 1 1 2 2 2 0 Swi5 ABC_tran_CTD PF16326.5 KEG10197.1 - 0.3 11.4 3.4 1.6 9.0 3.4 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 KEG10197.1 - 1.8 8.8 7.1 0.43 10.8 3.3 2.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain adh_short_C2 PF13561.6 KEG10199.1 - 3.4e-40 138.0 0.5 4.3e-40 137.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEG10199.1 - 1e-37 129.5 0.8 1.2e-37 129.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEG10199.1 - 1.3e-14 54.5 1.2 2.8e-14 53.4 1.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEG10199.1 - 2.1e-06 27.4 0.2 8.7e-06 25.4 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEG10199.1 - 0.0039 16.3 0.3 0.0062 15.7 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain CM2 PF03021.14 KEG10200.1 - 0.016 15.1 0.1 0.54 10.1 0.1 2.2 2 0 0 2 2 2 0 Influenza C virus M2 protein Aminopep PF10023.9 KEG10200.1 - 0.055 12.8 0.2 0.084 12.2 0.2 1.2 1 0 0 1 1 1 0 Putative aminopeptidase DUF4762 PF15959.5 KEG10200.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) Kinesin PF00225.23 KEG10203.1 - 2.7e-95 319.1 0.0 4.5e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG10203.1 - 8e-18 64.8 0.0 2.3e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Seryl_tRNA_N PF02403.22 KEG10203.1 - 0.37 11.1 6.3 1.2 9.4 0.6 3.0 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 KEG10203.1 - 7.1 6.4 24.8 0.43 10.4 4.5 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TK PF00265.18 KEG10204.1 - 4.9e-07 29.8 0.5 7.9e-07 29.1 0.5 1.4 1 0 0 1 1 1 1 Thymidine kinase TK PF00265.18 KEG10205.1 - 4.6e-17 62.4 0.0 5.6e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase Tfb5 PF06331.12 KEG10206.1 - 0.36 10.9 2.7 3.9 7.5 0.1 3.6 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 AHSP PF09236.10 KEG10206.1 - 1.2 9.6 7.7 28 5.2 0.1 4.5 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein IL5 PF02025.15 KEG10206.1 - 1.2 9.4 3.5 6.8 7.0 0.1 3.0 3 0 0 3 3 3 0 Interleukin 5 HTH_1 PF00126.27 KEG10207.1 - 0.042 13.8 3.9 0.29 11.1 0.7 3.2 2 1 1 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family LRR_6 PF13516.6 KEG10208.1 - 3.2e-14 51.7 33.7 0.019 15.0 0.0 10.9 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 KEG10208.1 - 0.00018 21.8 24.5 3.1 8.3 0.0 8.1 6 1 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG10208.1 - 0.2 12.3 22.5 2e+02 3.2 0.0 9.5 11 1 0 11 11 11 0 Leucine Rich Repeat BAF1_ABF1 PF04684.13 KEG10208.1 - 0.42 9.6 7.3 0.64 9.0 7.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCSAP PF15748.5 KEG10208.1 - 3.3 7.8 10.7 6.1 6.9 10.7 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2201_N PF13203.6 KEG10208.1 - 5 6.6 9.2 12 5.4 9.2 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.10 KEG10208.1 - 5.7 7.2 13.7 11 6.3 13.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Afi1 PF07792.12 KEG10208.1 - 6.7 7.2 10.1 18 5.8 10.1 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Aldo_ket_red PF00248.21 KEG10209.1 - 4.2e-52 177.2 0.0 1e-50 172.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TAL_effector PF03377.13 KEG10209.1 - 0.028 14.8 0.1 0.36 11.2 0.0 2.3 2 0 0 2 2 2 0 TAL effector repeat MinC_N PF05209.13 KEG10209.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Glyco_transf_15 PF01793.16 KEG10210.1 - 7e-08 32.1 0.1 9.6e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3337 PF11816.8 KEG10210.1 - 0.044 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Ribosomal_S5_C PF03719.15 KEG10211.1 - 4e-24 83.9 0.0 6.4e-24 83.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KEG10211.1 - 4.1e-21 74.7 0.7 6.7e-21 74.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 KEG10211.1 - 1.7 9.2 9.1 3.9 8.1 9.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 P16-Arc PF04699.14 KEG10212.1 - 0.055 14.0 0.2 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Baculo_PEP_C PF04513.12 KEG10213.1 - 0.006 16.6 0.8 0.006 16.6 0.8 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.24 KEG10213.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.1 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Ly49 PF08391.10 KEG10213.1 - 0.57 10.6 3.7 19 5.7 0.1 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PHM7_cyt PF14703.6 KEG10213.1 - 1.8 8.8 7.2 0.49 10.6 3.5 2.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Fzo_mitofusin PF04799.13 KEG10213.1 - 2.3 7.8 6.8 2.1 7.9 1.5 2.4 2 0 0 2 2 2 0 fzo-like conserved region WXG100 PF06013.12 KEG10213.1 - 2.4 8.4 8.1 1.7 8.9 3.6 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.12 KEG10213.1 - 4.3 7.4 13.1 9.3 6.3 2.8 2.9 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein XhlA PF10779.9 KEG10213.1 - 5.2 7.3 6.8 6.3 7.1 0.3 2.9 3 0 0 3 3 3 0 Haemolysin XhlA DUF948 PF06103.11 KEG10213.1 - 5.9 7.2 6.2 7.8 6.8 0.5 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Brix PF04427.18 KEG10214.1 - 8.6e-36 123.9 0.1 3.6e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 Brix domain Rtf2 PF04641.12 KEG10217.1 - 2.1e-20 73.2 0.0 5.7e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KEG10217.1 - 0.043 13.6 0.2 10 6.0 0.0 2.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KEG10217.1 - 0.051 13.7 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 KEG10217.1 - 0.095 12.7 0.5 0.3 11.1 0.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KEG10217.1 - 0.7 9.8 6.6 4.5 7.2 4.2 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 EF-hand_7 PF13499.6 KEG10218.1 - 0.0048 17.3 0.2 0.018 15.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG10218.1 - 0.0096 15.4 0.0 2.8 7.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KEG10218.1 - 0.098 12.5 0.3 0.48 10.3 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain pair Asp_protease PF09668.10 KEG10219.1 - 3.8e-52 175.3 0.9 5.5e-52 174.8 0.9 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KEG10219.1 - 1.2e-16 61.0 0.0 2.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA_4 PF14555.6 KEG10219.1 - 8.6e-08 31.9 0.1 1.7e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain Asp_protease_2 PF13650.6 KEG10219.1 - 3.7e-07 30.7 0.0 8.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1631 PF07793.11 KEG10219.1 - 0.0025 16.3 9.6 0.0025 16.3 9.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1631) ubiquitin PF00240.23 KEG10219.1 - 0.0029 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 KEG10219.1 - 0.0046 16.7 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 KEG10219.1 - 0.037 13.9 0.2 0.084 12.8 0.2 1.7 1 0 0 1 1 1 0 UBA/TS-N domain TFIIA PF03153.13 KEG10219.1 - 0.14 12.1 14.4 0.23 11.4 14.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 KEG10219.1 - 0.66 10.4 6.2 2.3 8.6 5.0 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3484 PF11983.8 KEG10219.1 - 0.71 11.0 9.7 0.12 13.5 5.0 2.2 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Lin-8 PF03353.15 KEG10219.1 - 1.1 8.8 4.5 1.8 8.1 4.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SARAF PF06682.12 KEG10219.1 - 2.7 7.6 6.7 5.4 6.6 6.7 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 KEG10219.1 - 4.9 7.8 16.1 0.47 11.1 11.2 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RabGAP-TBC PF00566.18 KEG10220.1 - 5.1e-27 94.9 0.0 8.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_ligase PF09414.10 KEG10221.1 - 6e-21 75.4 0.0 9.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 KEG10221.1 - 4.6e-05 23.5 0.0 9.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal DUF5308 PF17233.2 KEG10222.1 - 0.029 14.6 2.7 0.88 9.8 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Mtc PF03820.17 KEG10223.1 - 7.7e-89 297.8 0.4 8.6e-89 297.6 0.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PRP3 PF08572.10 KEG10224.1 - 1.1e-24 87.5 0.6 1.1e-24 87.5 0.6 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KEG10224.1 - 4.3e-13 49.6 1.4 6.2e-13 49.1 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PEARLI-4 PF05278.12 KEG10224.1 - 0.21 11.1 1.4 0.29 10.7 0.1 1.7 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) PGC7_Stella PF15549.6 KEG10224.1 - 0.63 10.0 4.2 0.92 9.5 2.4 2.0 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain cNMP_binding PF00027.29 KEG10228.1 - 2e-11 43.8 0.0 0.027 14.5 0.0 4.3 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain DNA_primase_S PF01896.19 KEG10229.1 - 3.8e-40 137.8 0.0 6.9e-40 137.0 0.0 1.4 1 1 0 1 1 1 1 DNA primase small subunit Phage_TAC_9 PF10876.8 KEG10229.1 - 0.15 12.1 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Phage tail assemb.y chaperone protein, TAC CCDC144C PF14915.6 KEG10233.1 - 0.0087 15.2 14.3 0.012 14.7 14.3 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region R3H-assoc PF13902.6 KEG10233.1 - 0.081 13.3 8.9 0.1 13.0 0.9 2.3 1 1 1 2 2 2 0 R3H-associated N-terminal domain Peptidase_S64 PF08192.11 KEG10233.1 - 0.088 11.3 2.0 0.1 11.0 2.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 FapA PF03961.13 KEG10233.1 - 0.25 9.9 1.9 0.34 9.4 1.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1515 PF07439.11 KEG10233.1 - 0.96 9.5 4.6 1.9 8.5 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) THF_DHG_CYH_C PF02882.19 KEG10234.1 - 1.6e-38 131.6 1.4 4.9e-38 130.0 1.4 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KEG10234.1 - 8.5e-26 90.5 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain BPS1 PF05633.11 KEG10234.1 - 0.038 13.0 0.2 0.063 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein BYPASS1-related Peptidase_M8 PF01457.16 KEG10236.1 - 1.6e-102 343.9 3.8 2.6e-51 174.9 0.0 2.0 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG10236.1 - 0.00046 20.4 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KEG10236.1 - 0.048 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.16 KEG10237.1 - 1.4e-31 109.8 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 KEG10238.1 - 3.7e-66 223.9 5.9 4.3e-61 207.2 5.4 2.1 1 1 1 2 2 2 2 Leishmanolysin PIG-X PF08320.12 KEG10241.1 - 1.9e-06 27.9 0.3 1.1e-05 25.4 0.3 1.9 1 1 0 1 1 1 1 PIG-X / PBN1 Kinesin PF00225.23 KEG10245.1 - 0.015 14.2 0.1 0.015 14.2 0.1 2.9 3 0 0 3 3 3 0 Kinesin motor domain SPECT1 PF18680.1 KEG10246.1 - 0.023 14.3 4.2 0.036 13.7 0.8 2.7 3 0 0 3 3 3 0 Plasmodium host cell traversal SPECT1 CPL PF08144.11 KEG10246.1 - 0.036 14.4 1.1 0.082 13.2 0.4 2.0 2 0 0 2 2 2 0 CPL (NUC119) domain PUMA PF15826.5 KEG10248.1 - 0.059 13.5 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis FYVE PF01363.21 KEG10250.1 - 0.0018 18.4 13.1 0.012 15.7 13.2 2.1 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KEG10250.1 - 0.12 12.6 8.8 0.23 11.7 8.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC_2 PF13913.6 KEG10250.1 - 0.36 10.8 0.2 0.36 10.8 0.2 3.6 3 1 1 4 4 4 0 zinc-finger of a C2HC-type Roughex PF06020.11 KEG10250.1 - 0.48 9.5 8.4 0.57 9.2 8.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SRP-alpha_N PF04086.13 KEG10250.1 - 0.89 9.4 6.9 1.1 9.1 6.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Siva PF05458.12 KEG10250.1 - 2.8 7.6 12.1 2.5 7.8 10.2 1.9 1 1 1 2 2 2 0 Cd27 binding protein (Siva) Ndc1_Nup PF09531.10 KEG10250.1 - 7.1 5.2 5.8 8.1 5.0 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EF-hand_6 PF13405.6 KEG10251.1 - 2.4e-08 33.2 0.1 1.8e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KEG10251.1 - 8.3e-08 32.6 0.9 8.8e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KEG10251.1 - 7.8e-07 28.3 0.1 2.3e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KEG10251.1 - 1.3e-06 27.5 0.3 2e-05 23.8 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KEG10251.1 - 3.7e-06 26.7 4.0 0.0091 15.8 0.2 2.9 2 1 1 3 3 3 3 EF-hand domain pair DUF3008 PF11450.8 KEG10251.1 - 0.0092 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) EF-hand_14 PF17959.1 KEG10251.1 - 0.065 13.6 0.3 0.24 11.8 0.1 2.1 2 1 0 2 2 2 0 EF-hand domain EF-hand_9 PF14658.6 KEG10251.1 - 0.13 12.7 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain MPP6 PF10175.9 KEG10251.1 - 0.31 11.5 1.7 0.59 10.6 1.7 1.4 1 1 0 1 1 1 0 M-phase phosphoprotein 6 Peptidase_S9 PF00326.21 KEG10252.1 - 6.3e-34 117.3 0.1 1.5e-33 116.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KEG10252.1 - 8.4e-30 103.7 0.0 1.5e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DLH PF01738.18 KEG10252.1 - 0.011 15.3 0.6 0.031 13.8 0.6 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KEG10252.1 - 0.013 16.1 1.9 0.033 14.8 0.3 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 KEG10252.1 - 0.11 11.9 0.3 0.22 10.8 0.3 1.5 1 1 0 1 1 1 0 Secretory lipase Glyco_hydro_49 PF03718.13 KEG10252.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 Cullin_Nedd8 PF10557.9 KEG10253.1 - 5.8e-16 58.3 0.3 1.3e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 KEG10253.1 - 0.00029 19.6 0.0 0.0013 17.5 0.0 2.0 3 0 0 3 3 3 1 Cullin family EF-hand_8 PF13833.6 KEG10254.1 - 0.0067 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG10254.1 - 0.077 12.6 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KEG10254.1 - 0.081 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain Radial_spoke PF04712.12 KEG10255.1 - 6.8e-117 391.4 0.0 8.5e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein PHO4 PF01384.20 KEG10256.1 - 8.5e-89 297.9 16.4 1e-88 297.7 16.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF436 PF04260.12 KEG10256.1 - 0.028 14.0 0.8 0.08 12.5 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF436) DcpS_C PF11969.8 KEG10257.1 - 1.4e-23 83.6 0.0 2.7e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KEG10257.1 - 1.3e-14 54.7 0.1 3.8e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 KEG10257.1 - 9.4e-08 32.4 1.3 1.2e-07 32.1 0.1 1.8 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Use1 PF09753.9 KEG10258.1 - 4.3e-05 23.4 0.0 4.8e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 ABC2_membrane_3 PF12698.7 KEG10259.1 - 1e-54 186.0 47.1 6.7e-35 120.8 18.6 3.5 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KEG10259.1 - 1e-52 178.3 0.0 7.7e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEG10259.1 - 4.6e-11 43.1 2.8 0.012 15.4 0.2 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG10259.1 - 2.8e-07 30.2 0.0 0.049 13.1 0.1 3.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG10259.1 - 0.00046 19.9 2.2 0.017 14.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KEG10259.1 - 0.001 18.8 0.2 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEG10259.1 - 0.0012 19.4 0.7 0.07 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KEG10259.1 - 0.0084 15.8 0.8 0.85 9.2 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KEG10259.1 - 0.0093 16.2 0.1 11 6.4 0.1 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KEG10259.1 - 0.092 12.4 0.5 0.23 11.2 0.0 1.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 KEG10259.1 - 0.49 9.0 0.8 1.6 7.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain zf-CCHC_2 PF13696.6 KEG10260.1 - 3.8e-08 33.0 2.9 6.9e-08 32.2 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 KEG10260.1 - 0.00025 21.3 1.9 0.00056 20.1 1.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-CCHC_5 PF14787.6 KEG10260.1 - 0.017 14.8 1.2 0.017 14.8 1.2 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C2H2_4 PF13894.6 KEG10260.1 - 0.026 15.3 0.8 0.026 15.3 0.8 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger Senescence_reg PF04520.13 KEG10260.1 - 0.037 14.9 4.3 0.062 14.1 2.7 2.1 2 0 0 2 2 2 0 Senescence regulator zf-C2H2 PF00096.26 KEG10260.1 - 0.087 13.3 8.6 1.5 9.4 3.6 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type eIF3g PF12353.8 KEG10260.1 - 0.088 13.2 5.3 0.11 12.8 0.2 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 KEG10260.1 - 0.13 12.4 1.8 0.32 11.2 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle SUIM_assoc PF16619.5 KEG10260.1 - 0.66 10.1 11.4 0.23 11.6 7.7 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Meleagrin PF08189.11 KEG10260.1 - 1.4 8.7 8.6 1.5 8.5 1.2 2.5 2 0 0 2 2 2 0 Meleagrin/Cygnin family Presenilin PF01080.17 KEG10260.1 - 3.2 6.4 3.4 3.9 6.1 3.4 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 KEG10260.1 - 3.5 7.2 8.4 5.8 6.5 8.4 1.3 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 KEG10261.1 - 3.4e-30 105.4 6.5 6.1e-30 104.6 6.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Peptidase_S15 PF02129.18 KEG10263.1 - 2e-62 211.2 2.2 4e-62 210.2 1.9 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEG10263.1 - 5.2e-36 124.7 0.0 7.3e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KEG10263.1 - 1.2e-09 37.8 0.1 4.7e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEG10263.1 - 1.5e-09 37.6 1.3 5.4e-08 32.6 0.7 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEG10263.1 - 6.5e-09 35.8 0.1 1.4e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KEG10263.1 - 3.9e-05 22.5 0.0 0.0024 16.6 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KEG10263.1 - 0.0015 19.2 2.7 0.0039 17.8 1.5 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KEG10263.1 - 0.063 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1100 PF06500.11 KEG10263.1 - 0.096 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) GTP_EFTU PF00009.27 KEG10264.1 - 2.7e-57 193.5 0.0 4.4e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KEG10264.1 - 5.8e-21 74.4 0.0 1.2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KEG10264.1 - 7.2e-15 54.8 0.1 1.4e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 KEG10264.1 - 1.6e-05 24.7 0.1 3.1e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KEG10264.1 - 4.4e-05 23.5 0.1 0.0001 22.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KEG10264.1 - 0.0003 21.1 0.0 0.00069 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AIG1 PF04548.16 KEG10264.1 - 0.01 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 KEG10264.1 - 0.03 13.8 0.0 0.1 12.1 0.0 1.9 1 0 0 1 1 1 0 Ferrous iron transport protein B LacAB_rpiB PF02502.18 KEG10265.1 - 2.4e-46 157.2 0.1 2.7e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KEG10265.1 - 0.0052 16.8 0.1 0.0091 16.0 0.1 1.4 1 0 0 1 1 1 1 Glycine-rich SFCGS DUF4256 PF14066.6 KEG10265.1 - 0.077 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) MTS_N PF08468.11 KEG10265.1 - 0.2 11.7 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal DUF3689 PF12463.8 KEG10266.1 - 0.001 18.5 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) LRR_6 PF13516.6 KEG10267.1 - 2.5e-16 58.3 5.7 0.029 14.4 0.1 6.8 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 KEG10267.1 - 2.2e-07 31.1 2.6 0.42 11.1 0.2 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10267.1 - 1.6e-05 24.6 4.7 0.27 11.0 0.0 4.6 3 2 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KEG10267.1 - 0.00018 21.6 0.5 1.1e+02 3.9 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat CAP_N PF01213.19 KEG10267.1 - 0.00028 20.5 3.0 0.00074 19.1 3.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DivIC PF04977.15 KEG10267.1 - 0.25 11.1 2.1 0.71 9.7 2.1 1.7 1 0 0 1 1 1 0 Septum formation initiator FAM76 PF16046.5 KEG10267.1 - 0.9 8.8 4.5 1.8 7.8 4.5 1.5 1 0 0 1 1 1 0 FAM76 protein Cytochrom_B558a PF05038.13 KEG10267.1 - 1.8 8.1 4.1 4 7.0 4.1 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit EF-hand_1 PF00036.32 KEG10270.1 - 1.7e-12 45.9 7.2 9.3e-07 28.0 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KEG10270.1 - 2.2e-11 42.7 1.7 2.3e-05 24.0 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KEG10270.1 - 1.2e-09 38.5 0.6 1.2e-05 25.7 0.0 3.9 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG10270.1 - 1.3e-08 34.5 3.9 0.015 15.1 0.0 5.8 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 KEG10270.1 - 4.4e-08 32.3 5.4 0.0051 16.3 0.0 4.6 4 0 0 4 4 4 3 EF hand RmlD_sub_bind PF04321.17 KEG10271.1 - 4.4e-05 22.7 0.0 0.065 12.3 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain AAA_lid_7 PF17867.1 KEG10271.1 - 0.22 11.7 0.5 0.9 9.8 0.1 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain Ribosomal_S6e PF01092.19 KEG10272.1 - 8.1e-43 145.4 1.1 1.1e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e eRF1_1 PF03463.15 KEG10272.1 - 0.0091 16.0 0.4 0.014 15.4 0.4 1.2 1 0 0 1 1 1 1 eRF1 domain 1 HTH_20 PF12840.7 KEG10273.1 - 0.023 14.8 0.7 0.023 14.8 0.7 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Guanylate_kin PF00625.21 KEG10274.1 - 5.9e-51 172.7 0.0 7.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KEG10274.1 - 1.6e-05 25.0 0.0 2.6e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KEG10274.1 - 4.7e-05 23.6 0.1 0.00011 22.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG10274.1 - 6.5e-05 23.5 0.2 0.00016 22.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG10274.1 - 0.0015 18.8 0.2 0.011 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KEG10274.1 - 0.0046 17.5 0.2 0.22 12.0 0.2 2.3 1 1 0 1 1 1 1 ABC transporter 2_5_RNA_ligase2 PF13563.6 KEG10274.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily AAA_16 PF13191.6 KEG10274.1 - 0.012 16.0 0.1 0.029 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KEG10274.1 - 0.015 15.3 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase dNK PF01712.19 KEG10274.1 - 0.043 13.7 0.2 3.4 7.5 0.1 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase ADK PF00406.22 KEG10274.1 - 0.045 13.8 0.7 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_17 PF13207.6 KEG10274.1 - 0.079 13.4 0.3 0.62 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEG10274.1 - 0.085 12.8 0.1 0.53 10.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) YEATS PF03366.16 KEG10275.1 - 9e-11 41.6 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family CbtA PF09490.10 KEG10275.1 - 0.021 14.6 0.2 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) PBP1_TM PF14812.6 KEG10275.1 - 2.8 8.4 6.1 2 8.9 1.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Voltage_CLC PF00654.20 KEG10276.1 - 1.2e-89 301.1 28.8 5.2e-89 299.0 26.1 2.4 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KEG10276.1 - 6e-06 26.6 3.1 0.00078 19.8 0.1 2.9 3 0 0 3 3 3 2 CBS domain Gly-zipper_YMGG PF13441.6 KEG10276.1 - 3.8 7.3 7.8 92 2.9 0.0 2.8 2 0 0 2 2 2 0 YMGG-like Gly-zipper Peptidase_S9 PF00326.21 KEG10277.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEG10277.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ThiD2 PF17792.1 KEG10278.1 - 0.56 10.7 5.6 0.29 11.6 1.1 2.7 2 1 0 2 2 2 0 ThiD2 family Fez1 PF06818.15 KEG10278.1 - 2.1 8.8 9.3 0.38 11.2 4.4 2.1 1 1 1 2 2 2 0 Fez1 CWC25 PF12542.8 KEG10278.1 - 2.8 8.9 6.3 0.42 11.5 0.2 2.9 3 2 0 3 3 3 0 Pre-mRNA splicing factor OCRE PF17780.1 KEG10280.1 - 0.00088 19.3 9.1 0.0017 18.4 9.1 1.4 1 0 0 1 1 1 1 OCRE domain PPTA PF01239.22 KEG10281.1 - 7.1e-25 86.0 11.0 1.3e-06 27.9 0.7 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Peptidase_M3 PF01432.20 KEG10282.1 - 6.3e-112 375.1 0.0 9.2e-112 374.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KEG10282.1 - 0.033 13.8 0.2 0.07 12.8 0.2 1.5 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_3 PF13570.6 KEG10283.1 - 0.0038 17.7 0.1 0.022 15.3 0.0 2.4 3 0 0 3 3 3 1 PQQ-like domain WD40 PF00400.32 KEG10283.1 - 0.017 16.0 1.4 1 10.3 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 KEG10284.1 - 1.6e-16 60.4 4.9 5.1e-06 27.1 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 KEG10284.1 - 1.2e-09 38.4 0.2 2.5e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KEG10284.1 - 1.5e-07 31.1 0.3 1.9e-06 27.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG10284.1 - 2.7e-07 30.0 0.2 0.001 18.9 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KEG10284.1 - 7.2e-07 28.3 0.1 4.2e-05 22.8 0.1 2.7 2 0 0 2 2 2 1 EF hand ANAPC4_WD40 PF12894.7 KEG10284.1 - 1.9e-06 28.1 0.0 0.0013 19.0 0.0 3.8 2 1 3 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 KEG10284.1 - 3e-05 23.3 0.1 7.7e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 EF hand Cytochrom_D1 PF02239.16 KEG10284.1 - 0.00042 19.0 0.1 0.00079 18.1 0.1 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain SPARC_Ca_bdg PF10591.9 KEG10284.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SLT_beta PF02258.16 KEG10284.1 - 0.037 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Shiga-like toxin beta subunit EF-hand_10 PF14788.6 KEG10284.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 EF hand Pro_dh PF01619.18 KEG10285.1 - 4.7e-64 216.8 0.0 7.4e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 KEG10285.1 - 0.023 15.1 0.0 0.056 13.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair CTP_transf_1 PF01148.20 KEG10286.1 - 3.4e-63 213.9 20.5 4.3e-63 213.6 20.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.18 KEG10287.1 - 4.3e-30 103.5 1.5 5.8e-30 103.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.18 KEG10288.1 - 8.1e-05 22.6 3.2 0.00096 19.2 0.2 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Utp12 PF04003.12 KEG10288.1 - 0.00017 21.8 0.9 0.001 19.3 0.1 2.5 2 2 0 2 2 2 1 Dip2/Utp12 Family LRR_6 PF13516.6 KEG10289.1 - 1e-14 53.2 14.5 1.2e-05 24.9 0.1 8.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 KEG10289.1 - 5.5e-05 23.5 2.6 4.2 7.9 0.1 6.0 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG10289.1 - 0.12 13.1 8.0 98 4.1 0.0 6.9 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 KEG10289.1 - 4.7 7.0 8.2 59 3.5 0.0 5.4 5 1 0 5 5 5 0 Leucine rich repeat PCI PF01399.27 KEG10290.1 - 1.1e-11 45.1 0.0 4.8e-11 43.1 0.0 2.1 2 1 0 2 2 2 1 PCI domain HyaE PF07449.11 KEG10290.1 - 0.075 13.0 0.0 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE UFD1 PF03152.14 KEG10292.1 - 7.6e-49 165.5 0.0 9.4e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 FbpC_C_terminal PF17845.1 KEG10292.1 - 0.082 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain Pkinase PF00069.25 KEG10293.1 - 3.9e-65 219.8 0.0 4.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10293.1 - 1.7e-32 112.8 0.0 2.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10293.1 - 1.9e-11 43.8 0.1 4.8e-11 42.5 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEG10293.1 - 1.2e-06 28.0 0.5 4.9e-06 26.0 0.3 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEG10293.1 - 0.0027 16.7 0.1 0.0043 16.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG10293.1 - 0.0082 16.1 0.2 0.21 11.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG10293.1 - 0.097 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family MAT1 PF06391.13 KEG10294.1 - 0.01 15.7 8.1 0.01 15.7 8.1 2.8 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 Vfa1 PF08432.10 KEG10294.1 - 2.5 8.4 31.2 0.47 10.8 8.9 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF2976 PF11190.8 KEG10295.1 - 0.1 12.4 2.9 0.65 9.8 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Cu_bind_like PF02298.17 KEG10296.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Plastocyanin-like domain Sec23_trunk PF04811.15 KEG10298.1 - 3.7e-50 170.8 0.0 5.4e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEG10298.1 - 6.5e-22 77.3 0.2 1.2e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KEG10298.1 - 3.5e-19 69.3 0.5 9.4e-19 67.9 0.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KEG10298.1 - 9.5e-12 44.8 3.9 2.1e-11 43.7 3.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KEG10298.1 - 8.3e-06 25.6 0.0 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KEG10298.1 - 0.055 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Phage_holin_2_1 PF04971.12 KEG10298.1 - 0.17 11.9 0.1 0.49 10.4 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage P21 holin S TB2_DP1_HVA22 PF03134.19 KEG10299.1 - 2.5e-05 24.1 0.6 6.5e-05 22.8 0.6 1.7 1 0 0 1 1 1 1 TB2/DP1, HVA22 family APG6 PF04111.12 KEG10301.1 - 1.7e-15 57.4 0.0 2.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain WD40 PF00400.32 KEG10302.1 - 4.2e-27 93.8 17.3 1.1e-05 26.0 0.1 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG10302.1 - 1.2e-13 51.1 10.1 9e-05 22.7 1.2 7.0 3 1 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KEG10302.1 - 9.3e-08 32.1 0.7 0.0022 18.0 0.1 4.7 6 0 0 6 6 6 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KEG10302.1 - 0.0013 18.1 0.2 5.7 6.2 0.0 4.1 3 1 1 4 4 4 1 WD40-like domain Nup160 PF11715.8 KEG10302.1 - 0.0016 17.2 4.5 0.42 9.2 0.2 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEG10302.1 - 0.0064 15.3 1.5 0.38 9.4 1.5 3.1 1 1 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.11 KEG10302.1 - 0.028 14.3 0.0 0.72 9.7 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Utp8 PF10395.9 KEG10302.1 - 0.14 10.6 0.0 2.7 6.4 0.0 2.2 1 1 1 2 2 2 0 Utp8 family BBS2_N PF14781.6 KEG10302.1 - 0.23 11.4 4.4 4.5 7.2 0.0 4.5 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, N-terminal WW PF00397.26 KEG10303.1 - 0.13 12.4 6.8 0.22 11.7 0.6 3.1 3 0 0 3 3 3 0 WW domain PWWP PF00855.17 KEG10304.1 - 0.00095 19.5 0.0 0.0037 17.7 0.0 2.0 1 0 0 1 1 1 1 PWWP domain Spt20 PF12090.8 KEG10305.1 - 2.8 7.5 13.7 0.94 9.0 10.4 1.8 2 0 0 2 2 2 0 Spt20 family SelP_N PF04592.14 KEG10305.1 - 7 6.0 41.7 0.49 9.8 36.2 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Mito_carr PF00153.27 KEG10308.1 - 3e-49 164.9 3.2 2.5e-18 65.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4235 PF14019.6 KEG10308.1 - 0.017 15.2 0.0 2.3 8.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) NHL PF01436.21 KEG10309.1 - 0.00012 22.0 3.8 0.028 14.5 0.1 3.7 4 0 0 4 4 4 2 NHL repeat Rax2 PF12768.7 KEG10310.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SecA_DEAD PF07517.14 KEG10311.1 - 1.4e-28 100.0 0.0 3.3e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 KEG10311.1 - 1.9e-06 28.5 0.4 1.3e-05 25.8 0.1 2.5 2 0 0 2 2 2 1 SecA preprotein cross-linking domain DEAD PF00270.29 KEG10311.1 - 0.0074 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPR_2 PF07719.17 KEG10311.1 - 0.024 14.7 0.4 0.024 14.7 0.4 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG10311.1 - 0.23 11.2 1.3 0.75 9.5 1.3 2.0 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.28 KEG10311.1 - 5.4 7.0 5.8 2.7 7.9 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG10311.1 - 9.8 6.9 9.7 1.2 9.9 4.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Csm1_N PF18504.1 KEG10312.1 - 0.012 15.9 3.3 0.022 15.1 2.4 2.0 1 1 0 1 1 1 0 Csm1 N-terminal domain DUF3450 PF11932.8 KEG10312.1 - 0.067 12.5 5.4 0.096 12.0 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Troponin PF00992.20 KEG10312.1 - 0.07 13.4 7.9 0.14 12.4 7.9 1.5 1 0 0 1 1 1 0 Troponin Mod_r PF07200.13 KEG10312.1 - 0.08 13.0 7.9 0.14 12.3 7.9 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FMN_bind_2 PF04299.12 KEG10312.1 - 0.19 11.5 0.3 0.31 10.7 0.3 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain Pinin_SDK_memA PF04696.13 KEG10312.1 - 0.57 10.2 11.3 1.7 8.7 9.9 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Spc24 PF08286.11 KEG10312.1 - 1.3 9.3 5.1 2 8.7 4.3 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 KEG10312.1 - 1.3 9.5 13.7 4.4 7.8 13.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 KEG10313.1 - 0.00087 19.4 9.5 0.001 19.2 9.5 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TraC PF07820.12 KEG10313.1 - 0.0043 17.4 1.7 0.0066 16.8 1.7 1.3 1 0 0 1 1 1 1 TraC-like protein PhaP_Bmeg PF09602.10 KEG10313.1 - 0.01 15.7 2.6 0.012 15.6 2.6 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Spc7 PF08317.11 KEG10313.1 - 0.012 14.5 9.9 0.013 14.4 9.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein GIT_CC PF16559.5 KEG10313.1 - 0.013 15.3 5.1 0.019 14.8 4.6 1.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Tropomyosin_1 PF12718.7 KEG10313.1 - 0.014 15.5 10.1 0.016 15.3 10.1 1.0 1 0 0 1 1 1 0 Tropomyosin like Atg14 PF10186.9 KEG10313.1 - 0.019 14.1 7.5 0.02 14.0 7.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KEG10313.1 - 0.032 14.3 10.2 0.044 13.9 10.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FliD_N PF02465.18 KEG10313.1 - 0.037 14.7 1.7 0.042 14.6 1.7 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.9 KEG10313.1 - 0.045 13.8 10.1 0.054 13.5 10.1 1.0 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KEG10313.1 - 0.045 14.0 9.9 0.051 13.8 9.9 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 MT PF12777.7 KEG10313.1 - 0.06 12.4 0.8 0.07 12.1 0.8 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor FmiP_Thoc5 PF09766.9 KEG10313.1 - 0.063 12.6 8.3 0.072 12.4 8.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Lipoprotein_20 PF13942.6 KEG10313.1 - 0.089 12.7 5.8 0.099 12.6 5.8 1.1 1 0 0 1 1 1 0 YfhG lipoprotein AAA_13 PF13166.6 KEG10313.1 - 0.1 11.3 6.5 0.1 11.2 6.5 1.0 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 KEG10313.1 - 0.11 13.0 12.5 0.14 12.7 12.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HemX PF04375.14 KEG10313.1 - 0.12 11.7 5.6 0.13 11.6 5.6 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase BST2 PF16716.5 KEG10313.1 - 0.12 12.9 9.5 0.13 12.8 9.5 1.0 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF3450 PF11932.8 KEG10313.1 - 0.13 11.5 8.3 0.15 11.3 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Macoilin PF09726.9 KEG10313.1 - 0.14 10.7 5.8 0.15 10.6 5.8 1.0 1 0 0 1 1 1 0 Macoilin family Ax_dynein_light PF10211.9 KEG10313.1 - 0.15 12.0 8.6 0.2 11.6 8.6 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DUF641 PF04859.12 KEG10313.1 - 0.17 12.3 5.1 0.19 12.1 5.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SIKE PF05769.11 KEG10313.1 - 0.19 11.6 10.7 0.6 10.0 1.0 2.0 1 1 1 2 2 2 0 SIKE family T3SSipB PF16535.5 KEG10313.1 - 0.22 12.0 4.9 0.25 11.8 4.9 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB AAA_lid_9 PF17871.1 KEG10313.1 - 0.32 11.0 5.1 0.36 10.8 5.1 1.2 1 0 0 1 1 1 0 AAA lid domain FlaC_arch PF05377.11 KEG10313.1 - 0.4 11.1 4.4 1.7 9.1 1.4 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KEG10313.1 - 0.49 10.2 13.4 0.24 11.2 10.6 1.7 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 KEG10313.1 - 0.57 10.0 6.5 0.65 9.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 KEG10313.1 - 0.92 10.0 6.8 1.3 9.5 6.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 KEG10313.1 - 0.97 9.5 9.1 1 9.5 9.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HSCB_C PF07743.13 KEG10313.1 - 0.97 10.0 11.9 5.4 7.6 0.5 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4407 PF14362.6 KEG10313.1 - 1.1 8.5 4.9 1.3 8.3 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KEG10313.1 - 1.8 8.8 7.3 2.4 8.5 7.1 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 KEG10313.1 - 1.9 7.7 4.1 1.9 7.7 4.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein IFT20 PF14931.6 KEG10313.1 - 2.2 8.5 11.7 3 8.0 11.7 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 ZapB PF06005.12 KEG10313.1 - 2.8 8.4 14.9 4.2 7.9 14.9 1.4 1 1 0 1 1 1 0 Cell division protein ZapB XhlA PF10779.9 KEG10313.1 - 3.3 8.0 7.0 2.7 8.3 5.1 1.7 1 1 1 2 2 2 0 Haemolysin XhlA DUF4337 PF14235.6 KEG10313.1 - 3.8 7.6 6.2 4.4 7.4 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Borrelia_P83 PF05262.11 KEG10313.1 - 4.9 5.5 9.1 5.2 5.5 9.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Ras PF00071.22 KEG10315.1 - 4.3e-47 159.7 0.0 5.1e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG10315.1 - 2.1e-27 95.7 0.0 4.1e-27 94.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG10315.1 - 5.3e-08 32.5 0.0 6.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG10315.1 - 0.00034 20.0 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEG10315.1 - 0.00043 19.9 0.0 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RIB43A PF05914.12 KEG10317.1 - 1.3e-75 254.6 63.4 1.6e-75 254.2 63.4 1.0 1 0 0 1 1 1 1 RIB43A zf-RanBP PF00641.18 KEG10318.1 - 8.1e-11 41.0 23.6 3.7e-05 22.9 4.5 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 KEG10318.1 - 7.2e-07 29.1 15.7 0.00073 19.5 8.6 2.4 1 1 1 2 2 2 2 Double zinc ribbon Ima1_N PF09779.9 KEG10318.1 - 0.37 11.6 0.1 0.37 11.6 0.1 3.4 2 2 1 3 3 3 0 Ima1 N-terminal domain zinc_ribbon_2 PF13240.6 KEG10318.1 - 2.3 8.0 22.3 1.5 8.7 2.6 3.6 3 1 0 3 3 3 0 zinc-ribbon domain DUF5354 PF17305.2 KEG10319.1 - 0.018 15.3 0.2 0.04 14.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5354) TMEM95 PF15203.6 KEG10320.1 - 4.4 6.9 7.0 1.6 8.3 3.7 1.9 2 0 0 2 2 2 0 TMEM95 family Atx10homo_assoc PF09759.9 KEG10321.1 - 1.5e-22 79.4 0.0 4.1e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain WAPL PF07814.13 KEG10321.1 - 0.018 13.8 0.3 0.021 13.6 0.3 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Myb_DNA-bind_7 PF15963.5 KEG10321.1 - 0.082 12.8 0.5 0.23 11.4 0.2 1.9 1 1 1 2 2 2 0 Myb DNA-binding like LRR_6 PF13516.6 KEG10326.1 - 1.1e-30 103.0 17.9 0.0013 18.6 0.0 9.7 10 0 0 10 10 10 8 Leucine Rich repeat LRR_4 PF12799.7 KEG10326.1 - 5.5e-11 42.5 17.3 0.0011 19.3 0.8 7.1 4 3 5 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10326.1 - 1.2e-09 37.8 17.4 0.066 13.0 4.0 7.6 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 KEG10326.1 - 0.00096 19.4 20.7 22 6.1 1.2 8.3 7 2 0 7 7 7 1 Leucine Rich Repeat SdiA-regulated PF06977.11 KEG10326.1 - 0.2 10.8 0.0 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 SdiA-regulated Yip1 PF04893.17 KEG10327.1 - 2.1e-07 30.9 17.9 3.7e-07 30.0 17.5 1.6 1 1 1 2 2 2 1 Yip1 domain DUF2632 PF10943.8 KEG10327.1 - 8 6.0 15.7 3.2 7.3 13.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2632) GATase PF00117.28 KEG10328.1 - 3e-10 40.2 0.1 4.1e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEG10328.1 - 1.3e-06 28.3 1.9 1.7e-05 24.7 0.4 2.8 2 1 0 2 2 2 1 Peptidase C26 tRNA-synt_2 PF00152.20 KEG10329.1 - 3.5e-79 266.1 0.0 4.4e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEG10329.1 - 8.8e-11 41.6 0.2 2.1e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEG10329.1 - 2.8e-08 33.6 0.1 0.00036 20.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MHC_I_2 PF14586.6 KEG10329.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 FAD-oxidase_C PF02913.19 KEG10330.1 - 2.3e-54 184.7 0.0 3.5e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEG10330.1 - 4.5e-36 123.7 0.2 7.7e-36 122.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain LRR_4 PF12799.7 KEG10331.1 - 1.1e-05 25.7 0.1 1 9.9 0.1 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10331.1 - 0.0074 16.0 0.0 15 5.4 0.0 4.3 3 1 1 4 4 4 1 Leucine rich repeat LRR_9 PF14580.6 KEG10331.1 - 0.025 14.1 0.1 6.2 6.3 0.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeat WD40 PF00400.32 KEG10332.1 - 2.3e-05 25.1 15.1 0.033 15.1 0.4 6.9 7 0 0 7 7 7 2 WD domain, G-beta repeat NACHT PF05729.12 KEG10332.1 - 5.4e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF2415 PF10313.9 KEG10332.1 - 0.0064 16.4 0.3 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Beach PF02138.18 KEG10334.1 - 3.6e-96 321.8 0.0 6.3e-96 321.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KEG10334.1 - 6.8e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily McrBC PF10117.9 KEG10334.1 - 0.2 10.7 0.1 0.38 9.8 0.1 1.3 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component eIF3_subunit PF08597.10 KEG10334.1 - 0.78 9.6 5.2 1.6 8.5 5.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit UQ_con PF00179.26 KEG10336.1 - 3e-35 120.9 0.0 4.5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aminotran_5 PF00266.19 KEG10338.1 - 1.9e-26 92.9 0.0 2.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KEG10338.1 - 0.047 12.2 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 KEG10339.1 - 1e-53 182.4 0.0 5.3e-37 127.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10339.1 - 4e-33 114.8 0.0 8.2e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10339.1 - 1.6e-09 37.5 0.0 3.3e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KEG10339.1 - 0.05 12.7 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pribosyltran PF00156.27 KEG10340.1 - 4.3e-21 75.1 0.1 8.6e-21 74.1 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 KEG10341.1 - 5.5e-19 68.2 0.0 8.4e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2730 PF10805.8 KEG10342.1 - 0.0032 17.5 0.1 0.0086 16.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) Peptidase_M24 PF00557.24 KEG10343.1 - 9e-42 143.1 0.1 1.3e-41 142.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3499 PF12005.8 KEG10343.1 - 0.61 10.7 5.4 0.21 12.2 1.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3499) DUF4833 PF16117.5 KEG10344.1 - 7.5e-19 68.1 0.1 4.1e-09 36.6 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) DUF2009 PF09418.10 KEG10344.1 - 0.029 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Gypsy PF07253.11 KEG10345.1 - 0.078 11.5 0.1 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 Gypsy protein CX9C PF16860.5 KEG10345.1 - 0.3 11.2 1.2 0.51 10.4 1.2 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GSH_synth_ATP PF03917.17 KEG10346.1 - 1.3e-69 234.8 0.0 1.4e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KEG10346.1 - 3.7e-31 107.6 0.0 1.2e-29 102.8 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic glutathione synthase SLATT_1 PF18181.1 KEG10346.1 - 0.005 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 1 Pam16 PF03656.13 KEG10346.1 - 0.13 12.2 0.4 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Pam16 DNA_pol_A PF00476.20 KEG10347.1 - 1.2e-37 129.9 0.2 1.6e-36 126.2 0.0 2.6 3 1 0 3 3 3 1 DNA polymerase family A DUF835 PF05763.12 KEG10348.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF835) DELLA PF12041.8 KEG10348.1 - 0.065 13.1 2.3 0.1 12.5 0.7 2.1 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Mannitol_dh_C PF08125.13 KEG10349.1 - 4e-56 190.2 0.0 5.9e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KEG10349.1 - 1.7e-33 115.9 0.0 2.6e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Cnd2 PF05786.14 KEG10350.1 - 2.1e-14 53.2 0.1 2.1e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 Condensin complex subunit 2 NAD_kinase PF01513.21 KEG10351.1 - 1.6e-11 43.9 0.0 2.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase CLN3 PF02487.17 KEG10352.1 - 1.6e-19 70.3 12.1 1.9e-19 70.0 12.1 1.0 1 0 0 1 1 1 1 CLN3 protein OB_NTP_bind PF07717.16 KEG10353.1 - 0.071 13.5 0.1 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Ashwin PF15323.6 KEG10353.1 - 0.33 11.0 0.2 0.33 11.0 0.2 1.7 2 0 0 2 2 2 0 Developmental protein TPR_12 PF13424.6 KEG10354.1 - 2.9e-08 33.9 1.5 2.9e-08 33.9 1.5 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEG10354.1 - 2.6e-06 27.1 1.4 0.0021 17.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG10354.1 - 0.00057 19.6 2.4 0.073 12.9 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10354.1 - 0.0028 17.6 0.6 0.064 13.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Hemerythrin PF01814.23 KEG10354.1 - 0.63 10.7 2.5 0.83 10.3 0.3 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain TPR_19 PF14559.6 KEG10354.1 - 1.5 9.4 5.6 0.35 11.4 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 KEG10355.1 - 0.0064 16.7 0.8 0.0064 16.7 0.8 4.3 4 1 1 5 5 5 2 ABC transporter C-terminal domain Tweety PF04906.13 KEG10355.1 - 0.3 9.7 1.9 0.45 9.1 1.5 1.4 1 1 0 1 1 1 0 Tweety NPV_P10 PF05531.12 KEG10355.1 - 0.6 10.6 4.4 23 5.5 0.2 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KEG10355.1 - 1.2 8.5 22.6 0.6 9.4 10.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 KEG10355.1 - 1.3 9.4 13.2 11 6.5 0.6 3.9 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM76 PF16046.5 KEG10355.1 - 7.7 5.8 15.4 0.33 10.3 7.6 2.0 1 1 1 2 2 2 0 FAM76 protein Kinesin PF00225.23 KEG10356.1 - 1.8e-05 23.9 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG10356.1 - 0.0018 18.2 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding CTU2 PF10288.9 KEG10359.1 - 8.8e-05 22.7 0.2 0.00021 21.5 0.2 1.7 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KEG10359.1 - 0.018 14.8 0.0 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 PP-loop family DUF5577 PF17740.1 KEG10359.1 - 0.17 11.5 0.0 0.51 10.0 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5577) Pkinase PF00069.25 KEG10360.1 - 1.4e-36 126.2 0.1 3.8e-31 108.4 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10360.1 - 3.1e-17 62.7 0.0 1.1e-16 61.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10360.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like TRI5 PF06330.11 KEG10360.1 - 0.07 12.0 0.1 9.1 5.0 0.1 2.2 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) DSPc PF00782.20 KEG10361.1 - 2.4e-07 30.6 0.4 6.5e-07 29.2 0.1 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG10361.1 - 0.0051 16.4 0.2 1.6 8.3 0.1 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase C2 PF00168.30 KEG10362.1 - 5.4e-21 74.8 0.0 1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain PepX_C PF08530.10 KEG10363.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain ubiquitin PF00240.23 KEG10365.1 - 3.5e-08 33.1 0.0 7.4e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KEG10365.1 - 0.00041 20.9 0.6 0.0024 18.4 0.6 2.1 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEG10365.1 - 0.046 13.8 0.1 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.13 KEG10365.1 - 0.65 10.6 6.8 1.9 9.1 6.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PseudoU_synth_2 PF00849.22 KEG10366.1 - 1.5e-20 73.9 0.0 2.4e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_1 PF00515.28 KEG10367.1 - 6.4e-10 38.4 4.5 0.014 15.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10367.1 - 5.2e-09 35.5 5.0 0.03 14.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEG10367.1 - 4.6e-07 30.0 4.6 5.2e-06 26.7 1.0 2.8 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG10367.1 - 1.1e-06 29.1 4.1 1.8e-06 28.5 0.8 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG10367.1 - 1.7e-06 27.8 2.0 0.28 11.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG10367.1 - 6.1e-05 23.1 1.7 0.63 10.5 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG10367.1 - 0.00043 20.7 0.2 0.12 13.1 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG10367.1 - 0.0016 18.3 1.1 3 8.1 0.2 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG10367.1 - 0.0018 18.5 2.2 0.006 16.8 0.9 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEG10367.1 - 0.0028 17.8 0.1 0.0067 16.5 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEG10367.1 - 0.02 15.5 2.0 4.7 8.1 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG10367.1 - 0.021 15.3 6.2 0.41 11.2 0.2 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG10367.1 - 0.023 14.5 4.6 0.17 11.8 0.1 3.5 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG10367.1 - 0.031 15.1 2.0 1.7 9.7 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG10367.1 - 0.038 13.7 0.5 8.8 6.1 0.0 2.9 3 0 0 3 3 3 0 TPR repeat MRP-L47 PF06984.13 KEG10368.1 - 9.5e-26 89.8 0.1 1.9e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) A_deaminase PF00962.22 KEG10369.1 - 3.6e-125 417.6 0.0 7.1e-75 252.3 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase CENP-H PF05837.12 KEG10369.1 - 1.3 9.5 8.2 3.9 7.9 8.2 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KEG10369.1 - 4.5 7.8 13.6 14 6.2 13.6 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region Gon7 PF08738.10 KEG10369.1 - 6.4 6.9 7.6 11 6.1 5.5 2.4 2 0 0 2 2 2 0 Gon7 family ADH_N PF08240.12 KEG10370.1 - 3.4e-05 23.7 0.3 6.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RNB PF00773.19 KEG10372.1 - 4.1e-57 194.0 0.0 6.4e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain DUF5470 PF17564.2 KEG10373.1 - 0.18 12.0 6.6 2.2 8.5 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5470) DHC_N2 PF08393.13 KEG10374.1 - 4.1e-46 157.9 1.1 2.5e-45 155.3 1.7 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KEG10374.1 - 7.6e-11 41.5 0.0 2.2e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 KEG10374.1 - 2.6e-10 40.1 0.0 6.8e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF3481 PF11980.8 KEG10375.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Rx_N PF18052.1 KEG10376.1 - 0.61 10.4 2.8 7.8 6.9 0.1 3.0 2 0 0 2 2 2 0 Rx N-terminal domain Kinesin PF00225.23 KEG10377.1 - 0.0089 15.0 0.0 2.6 6.9 0.0 2.9 2 1 0 2 2 2 2 Kinesin motor domain tRNA_lig_kinase PF08303.11 KEG10378.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA ligase kinase domain Hydin_ADK PF17213.3 KEG10380.1 - 0.35 11.1 16.2 0.56 10.4 6.6 3.0 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain SUIM_assoc PF16619.5 KEG10380.1 - 1.3 9.1 0.0 1.3 9.1 0.0 6.1 4 2 1 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 VPS13 PF16908.5 KEG10382.1 - 4.7e-17 62.6 0.0 8.4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KEG10382.1 - 8.4e-15 54.9 0.1 3.1e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 CENP-B_dimeris PF09026.10 KEG10382.1 - 0.024 15.0 10.0 0.052 13.9 10.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ANAPC15 PF15243.6 KEG10382.1 - 0.087 13.2 5.7 0.28 11.6 5.9 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 PUB PF09409.10 KEG10383.1 - 2.2e-10 40.3 0.0 5.4e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PUB domain zf_C2H2_6 PF18450.1 KEG10383.1 - 0.031 14.0 0.7 0.07 12.9 0.7 1.7 1 0 0 1 1 1 0 Zinc Finger domain Myosin_head PF00063.21 KEG10384.1 - 2.8e-98 329.9 0.0 2.5e-90 303.6 0.0 2.4 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.12 KEG10384.1 - 0.00035 19.9 0.0 0.0011 18.3 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KEG10384.1 - 0.001 19.4 2.6 0.0045 17.4 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KEG10384.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Kringle PF00051.18 KEG10385.1 - 1.8e-18 66.6 1.4 3.8e-18 65.6 1.4 1.6 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C_1 PF13290.6 KEG10385.1 - 1.5e-12 47.3 0.2 3e-11 43.1 0.1 2.8 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 KEG10385.1 - 1.9e-11 43.9 0.1 5e-10 39.4 0.1 2.7 2 0 0 2 2 2 1 Fn3 associated TMEM18 PF14770.6 KEG10385.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 18 Exostosin PF03016.15 KEG10386.1 - 2.3e-07 30.4 0.0 3.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Exostosin family FA_desaturase PF00487.24 KEG10387.1 - 0.021 14.6 0.1 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase SAYSvFN PF10260.9 KEG10387.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.15 KEG10387.1 - 0.18 11.7 8.9 0.3 11.1 8.9 1.3 1 0 0 1 1 1 0 SEC-C motif Glyco_transf_25 PF01755.17 KEG10388.1 - 0.0013 18.7 0.0 0.0089 15.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF5564 PF17719.1 KEG10388.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5564) MMR_HSR1 PF01926.23 KEG10389.1 - 1.3e-14 54.2 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG10389.1 - 6.1e-10 38.8 0.0 2.6e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEG10389.1 - 7.8e-05 22.8 0.3 0.022 14.8 0.1 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KEG10389.1 - 0.0007 19.5 0.2 0.0046 16.9 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEG10389.1 - 0.0012 18.5 0.0 0.048 13.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KEG10389.1 - 0.0042 17.3 5.3 0.36 11.1 0.1 3.6 3 2 0 3 3 3 2 AAA domain SRPRB PF09439.10 KEG10389.1 - 0.0047 16.4 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEG10389.1 - 0.0085 15.3 0.0 0.019 14.1 0.0 1.5 2 0 0 2 2 2 1 G-protein alpha subunit AAA_21 PF13304.6 KEG10389.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KEG10389.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KEG10389.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KEG10389.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain TFIIB PF00382.19 KEG10390.1 - 2.6e-22 78.6 0.0 5.9e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KEG10390.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1935 PF09149.10 KEG10391.1 - 3.9e-26 91.4 0.0 4.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.6 KEG10392.1 - 1.4e-13 51.0 0.0 4.5e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain FPN1 PF06963.12 KEG10392.1 - 0.094 11.3 0.1 0.16 10.5 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2722 PF10846.8 KEG10392.1 - 0.1 11.5 2.9 0.19 10.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1935 PF09149.10 KEG10393.1 - 8.5e-12 45.4 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 KEG10394.1 - 3.4e-31 107.7 0.1 5.1e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.18 KEG10395.1 - 6.3e-10 38.7 0.3 2.2e-09 36.9 0.2 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Mcp5_PH PF12814.7 KEG10398.1 - 3.1e-12 46.7 0.5 5.2e-12 46.0 0.5 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KEG10398.1 - 7.3e-05 23.2 0.1 0.00014 22.3 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_12 PF16457.5 KEG10398.1 - 0.022 15.3 0.2 0.08 13.5 0.2 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 KEG10398.1 - 0.025 14.9 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region ACOX PF01756.19 KEG10399.1 - 1.2e-08 34.7 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Spt5-NGN PF03439.13 KEG10400.1 - 5e-20 71.2 1.1 8.7e-20 70.4 0.1 2.0 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KEG10400.1 - 7.5e-07 30.1 1.3 7.5e-07 30.1 1.3 3.1 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KEG10400.1 - 1.4e-06 28.1 12.6 0.0086 16.0 0.8 4.4 4 0 0 4 4 4 2 KOW motif HAS-barrel PF09378.10 KEG10400.1 - 0.024 14.8 0.4 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 HAS barrel domain GntR PF00392.21 KEG10400.1 - 0.037 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family BUD22 PF09073.10 KEG10400.1 - 1 8.6 20.2 1.5 8.1 20.2 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 KEG10400.1 - 2.8 7.7 10.9 5.1 6.8 10.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.12 KEG10400.1 - 4.4 5.8 25.0 6.4 5.2 25.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleo_P87 PF07267.11 KEG10400.1 - 7.5 5.3 5.9 13 4.5 5.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MORN PF02493.20 KEG10401.1 - 2e-14 52.5 20.7 2.8e-06 26.9 0.6 5.2 6 0 0 6 6 6 4 MORN repeat DUF3048_C PF17479.2 KEG10401.1 - 0.066 13.6 0.7 1.7 9.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain PP2C PF00481.21 KEG10403.1 - 1.1e-75 254.6 0.0 1.4e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KEG10403.1 - 1.9e-06 27.7 0.1 3.1e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4488 PF14869.6 KEG10403.1 - 0.079 12.9 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4488) YchF-GTPase_C PF06071.13 KEG10404.1 - 1.1e-38 131.2 0.5 2.5e-38 130.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KEG10404.1 - 4.9e-21 75.0 0.0 1.3e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG10404.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KEG10404.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KEG10404.1 - 0.014 15.9 0.0 0.13 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain TGS PF02824.21 KEG10404.1 - 0.036 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 TGS domain NYD-SP28_assoc PF14775.6 KEG10405.1 - 0.023 14.8 0.3 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain BLOC1_2 PF10046.9 KEG10405.1 - 0.023 15.0 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Wtap PF17098.5 KEG10405.1 - 0.18 11.7 3.6 0.19 11.7 0.2 2.2 2 1 0 2 2 2 0 WTAP/Mum2p family Cpn60_TCP1 PF00118.24 KEG10406.1 - 5.8e-07 28.5 0.0 1.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TAN PF11640.8 KEG10406.1 - 0.047 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Ribosomal_L13e PF01294.18 KEG10407.1 - 2.7e-61 206.6 5.4 3.6e-61 206.2 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.19 KEG10407.1 - 0.021 14.8 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase HSP20 PF00011.21 KEG10408.1 - 3.1e-21 75.4 0.2 3.6e-21 75.2 0.2 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEG10408.1 - 1.2e-09 37.6 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PDEase_I PF00233.19 KEG10409.1 - 1e-74 251.3 1.9 1e-74 251.3 1.9 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase C4bp_oligo PF18453.1 KEG10409.1 - 0.042 14.0 0.0 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Oligomerization domain of C4b-binding protein alpha THEG PF14912.6 KEG10411.1 - 0.07 13.6 2.1 0.39 11.2 0.3 2.5 1 1 2 3 3 3 0 Testicular haploid expressed repeat E3_binding PF02817.17 KEG10412.1 - 0.38 11.1 1.5 2 8.8 0.5 2.4 2 0 0 2 2 2 0 e3 binding domain Acyltransferase PF01553.21 KEG10413.1 - 2.3e-09 36.9 0.0 5.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EF-hand_1 PF00036.32 KEG10413.1 - 0.0026 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KEG10413.1 - 0.0038 17.7 0.1 0.0076 16.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KEG10413.1 - 0.0058 16.1 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEG10413.1 - 0.091 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain SET PF00856.28 KEG10414.1 - 4.1e-05 24.0 0.1 0.16 12.4 0.0 2.8 2 1 1 3 3 3 2 SET domain FUSC PF04632.12 KEG10414.1 - 0.18 10.3 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NIF PF03031.18 KEG10415.1 - 5.6e-31 107.4 0.0 8.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 KEG10415.1 - 2.3e-05 24.1 0.1 3.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) PARP PF00644.20 KEG10416.1 - 9.1e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Fam20C PF06702.12 KEG10418.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 Pkinase PF00069.25 KEG10420.1 - 1e-45 156.2 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10420.1 - 3.8e-31 108.3 0.0 5.2e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG10420.1 - 6.8e-08 31.7 0.0 1.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG10420.1 - 1e-06 28.3 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEG10420.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG10420.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUIM_assoc PF16619.5 KEG10422.1 - 0.0095 16.0 4.4 0.012 15.7 2.5 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 PSK_trans_fac PF07704.11 KEG10422.1 - 0.25 12.1 4.1 0.19 12.5 1.0 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor Methyltr_RsmB-F PF01189.17 KEG10423.1 - 2.2e-20 73.2 0.0 1.7e-14 54.0 0.0 2.4 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 KEG10423.1 - 0.00069 19.5 1.6 0.0022 17.9 1.6 1.8 1 1 0 1 1 1 1 PUA domain Rab3-GTPase_cat PF13890.6 KEG10424.1 - 5.8e-45 152.8 0.0 1.1e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit CPBP PF02517.16 KEG10425.1 - 3.4e-16 59.4 0.2 3.4e-16 59.4 0.2 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease PBP1_TM PF14812.6 KEG10427.1 - 0.036 14.4 3.4 0.12 12.7 3.4 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1484 PF07363.11 KEG10427.1 - 0.13 13.3 0.4 0.31 12.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) LapA_dom PF06305.11 KEG10429.1 - 0.099 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SepQ PF06622.11 KEG10430.1 - 0.097 11.8 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 SepQ protein RNase_H2-Ydr279 PF09468.10 KEG10431.1 - 4.1e-07 30.3 0.0 7.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KEG10431.1 - 0.00011 22.3 0.0 0.00073 19.7 0.0 2.2 1 1 0 1 1 1 1 Ydr279p protein triple barrel domain DUF962 PF06127.11 KEG10432.1 - 6.2e-24 83.9 0.3 7e-24 83.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_C PF00137.21 KEG10432.1 - 0.0058 17.0 0.9 0.0064 16.8 0.0 1.5 2 0 0 2 2 2 1 ATP synthase subunit C PMT PF02366.18 KEG10432.1 - 0.017 14.8 1.5 0.02 14.5 1.5 1.0 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2198 PF09964.9 KEG10432.1 - 0.046 13.8 1.1 0.1 12.6 1.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) LRR_6 PF13516.6 KEG10433.1 - 5.9e-16 57.1 19.5 0.27 11.4 0.1 10.5 11 0 0 11 11 11 7 Leucine Rich repeat LRR_8 PF13855.6 KEG10433.1 - 0.00087 19.0 13.0 1.9 8.3 0.2 6.5 6 2 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 KEG10433.1 - 0.0011 19.3 11.9 0.21 12.1 0.1 6.1 6 2 0 6 6 6 2 Leucine Rich repeats (2 copies) BBL5 PF07289.11 KEG10436.1 - 2.5e-123 411.4 0.0 3e-123 411.1 0.0 1.1 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Voldacs PF03517.13 KEG10436.1 - 0.033 14.3 0.2 6.6 6.9 0.0 2.5 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling Pkinase PF00069.25 KEG10437.1 - 2.7e-66 223.6 0.0 3.1e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10437.1 - 4.7e-44 150.6 0.0 5.7e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10437.1 - 1.3e-07 31.3 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KEG10437.1 - 1e-05 25.6 2.7 9.8e-05 22.4 0.6 2.6 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG10437.1 - 0.0012 18.2 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEG10437.1 - 0.005 15.8 0.0 0.013 14.5 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KEG10437.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KEG10437.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KEG10437.1 - 0.023 13.8 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KEG10437.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Galactosyl_T PF01762.21 KEG10438.1 - 2.2e-05 24.3 0.2 0.065 13.0 0.1 3.4 2 1 1 3 3 3 1 Galactosyltransferase PsbU PF06514.11 KEG10438.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Aa_trans PF01490.18 KEG10439.1 - 3.5e-49 167.6 37.7 4.3e-49 167.3 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG10439.1 - 4.4e-07 29.3 16.0 4.4e-07 29.3 16.0 1.8 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family FA_hydroxylase PF04116.13 KEG10440.1 - 1.4e-15 57.8 16.9 1.4e-15 57.8 16.9 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PhaG_MnhG_YufB PF03334.14 KEG10440.1 - 0.037 14.3 5.0 0.63 10.3 0.4 2.4 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Use1 PF09753.9 KEG10441.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 RskA PF10099.9 KEG10441.1 - 0.036 14.4 1.6 0.06 13.6 1.6 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Hydrophobin_2 PF06766.11 KEG10441.1 - 0.14 12.2 2.9 2.1 8.4 0.4 2.4 2 0 0 2 2 2 0 Fungal hydrophobin SLS PF14611.6 KEG10441.1 - 0.15 11.9 0.1 0.48 10.2 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Ribosomal_L7Ae PF01248.26 KEG10442.1 - 0.15 11.8 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4381 PF14316.6 KEG10443.1 - 0.027 14.7 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FtsL PF04999.13 KEG10443.1 - 0.36 10.9 0.9 0.61 10.1 0.1 1.7 2 0 0 2 2 2 0 Cell division protein FtsL LRR_8 PF13855.6 KEG10444.1 - 9.3e-10 38.1 3.5 0.00044 20.0 0.4 3.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KEG10444.1 - 0.00033 20.8 6.5 19 6.3 0.0 6.5 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 KEG10444.1 - 0.00057 20.2 2.9 0.14 12.6 0.3 4.2 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG10444.1 - 0.095 12.8 4.0 8.5 6.7 0.0 5.4 8 0 0 8 8 8 0 Leucine Rich repeat LSM PF01423.22 KEG10445.1 - 1.3e-20 72.9 0.0 1.4e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEG10445.1 - 0.0001 22.4 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KEG10445.1 - 0.087 12.9 0.0 0.092 12.9 0.0 1.2 1 1 0 1 1 1 0 Scd6-like Sm domain CS PF04969.16 KEG10446.1 - 2.6e-08 34.8 0.6 3.7e-08 34.3 0.6 1.2 1 0 0 1 1 1 1 CS domain Beta_protein PF14350.6 KEG10446.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Beta protein ARL2_Bind_BART PF11527.8 KEG10447.1 - 0.0062 16.6 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Exotox-A_target PF09102.10 KEG10447.1 - 0.064 13.2 0.0 0.21 11.6 0.0 1.7 1 1 1 2 2 2 0 Exotoxin A, targeting DUF2569 PF10754.9 KEG10448.1 - 0.072 13.5 1.5 1.9 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) zf-ANAPC11 PF12861.7 KEG10449.1 - 3e-33 113.8 11.8 3.2e-33 113.6 11.8 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KEG10449.1 - 4.4e-21 74.9 15.9 6.2e-21 74.4 15.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEG10449.1 - 2.4e-06 27.8 20.5 4e-05 23.9 18.8 2.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG10449.1 - 0.00013 21.7 4.2 0.00013 21.7 4.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG10449.1 - 0.0011 18.8 16.6 0.0036 17.1 16.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG10449.1 - 0.006 16.6 12.9 0.0071 16.4 10.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEG10449.1 - 0.02 14.8 18.8 0.39 10.6 12.5 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG10449.1 - 0.052 13.5 21.3 0.78 9.8 20.3 2.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 KEG10449.1 - 0.6 9.9 16.0 7.9 6.3 16.0 2.3 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KEG10449.1 - 1 9.0 16.8 0.15 11.7 9.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KEG10449.1 - 4.1 7.3 11.3 14 5.6 11.3 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KEG10449.1 - 4.9 7.0 22.5 0.048 13.4 3.8 2.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1192 PF06698.11 KEG10450.1 - 0.081 13.0 0.4 0.18 11.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF962 PF06127.11 KEG10451.1 - 5.2e-22 77.7 3.1 1.8e-21 76.0 3.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF563 PF04577.14 KEG10453.1 - 1.6e-19 70.8 0.3 1.9e-19 70.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FPL PF09758.9 KEG10454.1 - 1.5e-52 177.6 0.8 2.4e-52 176.9 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein RBB1NT PF08169.11 KEG10455.1 - 0.17 12.0 0.0 0.7 10.1 0.0 1.9 2 0 0 2 2 2 0 RBB1NT (NUC162) domain MAT1-1-2 PF17043.5 KEG10457.1 - 0.041 13.7 0.2 0.046 13.6 0.2 1.2 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function LRR_4 PF12799.7 KEG10458.1 - 2.5e-09 37.3 10.0 0.036 14.5 0.0 5.1 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10458.1 - 8.1e-05 22.3 7.4 0.14 11.9 1.3 4.3 2 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 KEG10458.1 - 0.0014 18.5 11.7 4.1 7.7 0.1 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 KEG10458.1 - 0.0036 16.8 1.9 2 7.9 0.2 3.4 2 2 0 3 3 3 2 Leucine-rich repeat PH_12 PF16457.5 KEG10461.1 - 2.8e-07 31.1 0.6 1.6e-06 28.7 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain DUF4287 PF14117.6 KEG10461.1 - 0.13 12.4 0.1 0.52 10.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Arv1 PF04161.13 KEG10462.1 - 1.3e-20 74.4 4.5 1.8e-20 74.0 4.5 1.2 1 0 0 1 1 1 1 Arv1-like family FAM70 PF14967.6 KEG10462.1 - 0.016 14.7 0.4 0.024 14.1 0.4 1.3 1 0 0 1 1 1 0 FAM70 protein GSP_synth PF03738.14 KEG10463.1 - 2.1e-45 155.5 0.0 4.7e-38 131.3 0.0 2.1 1 1 1 2 2 2 2 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 KEG10463.1 - 2.1e-07 31.4 0.3 6.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 CHAP domain Ceramidase PF05875.12 KEG10464.1 - 0.038 13.4 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Ceramidase F-box-like PF12937.7 KEG10464.1 - 0.14 12.1 0.5 0.53 10.2 0.3 2.0 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 KEG10465.1 - 1.1e-53 182.3 0.0 1.9e-47 161.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10465.1 - 4.9e-24 85.0 0.0 2.4e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG10465.1 - 8.1e-06 25.9 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG10465.1 - 0.004 16.5 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEG10465.1 - 0.006 16.0 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family P5CR_dimer PF14748.6 KEG10466.1 - 2.2e-39 133.9 3.2 4.7e-39 132.8 3.2 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KEG10466.1 - 1.6e-21 76.6 0.0 4.4e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEG10466.1 - 4.1e-08 33.5 0.6 8.3e-08 32.6 0.2 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KEG10466.1 - 0.00016 21.8 0.0 0.00046 20.2 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KEG10466.1 - 0.0029 18.4 0.2 0.0092 16.8 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KEG10466.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GxGYxYP_N PF16216.5 KEG10466.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ApbA PF02558.16 KEG10466.1 - 0.03 14.0 0.3 0.051 13.2 0.3 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AA_permease_2 PF13520.6 KEG10466.1 - 0.061 12.1 0.9 0.074 11.9 0.9 1.1 1 0 0 1 1 1 0 Amino acid permease ADSL_C PF10397.9 KEG10466.1 - 0.072 13.6 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Med26 PF08711.11 KEG10467.1 - 0.002 18.1 2.3 0.12 12.4 0.1 2.4 2 0 0 2 2 2 2 TFIIS helical bundle-like domain Zip PF02535.22 KEG10467.1 - 0.67 9.1 2.4 0.92 8.7 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UBM PF14377.6 KEG10467.1 - 1.8 8.1 5.5 0.2 11.2 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin binding region NPR3 PF03666.13 KEG10467.1 - 5.1 5.8 13.0 7.3 5.3 13.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 KEG10467.1 - 8.7 5.7 8.3 17 4.7 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DnaB_C PF03796.15 KEG10468.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_33 PF13671.6 KEG10468.1 - 0.0048 17.1 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG10468.1 - 0.006 17.0 0.1 0.25 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KEG10468.1 - 0.0062 15.8 0.7 0.035 13.4 0.1 2.2 2 0 0 2 2 2 1 Zeta toxin ATPase PF06745.13 KEG10468.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KEG10468.1 - 0.055 13.0 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG10468.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEG10468.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KEG10468.1 - 0.13 12.7 0.0 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RabGAP-TBC PF00566.18 KEG10469.1 - 1e-42 146.3 5.2 1.4e-42 145.8 5.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KEG10469.1 - 9.3e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Rab-binding domain (RBD) Rotamase PF00639.21 KEG10470.1 - 1.8e-20 73.7 2.9 3.8e-20 72.6 0.0 2.4 2 0 0 2 2 2 1 PPIC-type PPIASE domain FHA PF00498.26 KEG10470.1 - 4.2e-18 65.4 0.0 7.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rotamase_3 PF13616.6 KEG10470.1 - 2e-11 44.5 0.0 6.7e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Yop-YscD_cpl PF16697.5 KEG10470.1 - 8.4e-06 26.0 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_2 PF13145.6 KEG10470.1 - 0.31 11.9 11.8 1.8 9.4 8.5 3.0 2 1 0 2 2 2 0 PPIC-type PPIASE domain PPR PF01535.20 KEG10471.1 - 5.5e-05 23.1 0.2 3.3 8.2 0.3 4.6 4 0 0 4 4 4 2 PPR repeat SUIM_assoc PF16619.5 KEG10471.1 - 0.25 11.4 8.2 0.048 13.7 1.8 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_16 PF13432.6 KEG10471.1 - 8.7 7.1 15.6 29 5.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Kinesin PF00225.23 KEG10472.1 - 2.8e-85 286.2 2.3 2.8e-85 286.2 2.3 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG10472.1 - 2.5e-20 72.9 0.3 8.6e-20 71.2 0.1 2.1 2 0 0 2 2 2 1 Microtubule binding BLOC1_2 PF10046.9 KEG10472.1 - 0.26 11.6 19.2 1.4 9.3 3.7 4.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRPM_tetra PF16519.5 KEG10472.1 - 0.84 9.8 7.2 0.58 10.3 2.6 3.1 2 1 0 2 2 2 0 Tetramerisation domain of TRPM LRR_4 PF12799.7 KEG10473.1 - 7.1e-14 51.7 11.7 2.2e-08 34.2 2.7 3.6 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG10473.1 - 2.9e-12 46.4 0.5 2.3e-06 27.3 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KEG10473.1 - 2.7e-10 39.8 4.7 1.7e-06 27.7 0.1 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KEG10473.1 - 0.15 12.7 4.9 9.3 7.2 0.2 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat Elf1 PF05129.13 KEG10474.1 - 0.0017 18.3 6.2 0.0028 17.7 3.6 2.2 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Fam20C PF06702.12 KEG10474.1 - 0.03 14.1 0.3 0.049 13.4 0.3 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 SNF2_N PF00176.23 KEG10475.1 - 6.9e-38 130.3 0.0 1.1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG10475.1 - 9.5e-14 51.7 0.0 4.3e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG10475.1 - 1.9e-08 34.5 0.0 4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KEG10475.1 - 0.0056 16.4 0.0 0.049 13.3 0.0 2.1 1 1 0 1 1 1 1 SWI2/SNF2 ATPase SUIM_assoc PF16619.5 KEG10476.1 - 1.1 9.4 21.4 3.5 7.8 2.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG10476.1 - 1.5 8.4 21.9 3.6 7.1 14.8 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 KEG10476.1 - 1.8 8.5 16.3 7.8 6.4 11.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AXIN1_TNKS_BD PF16646.5 KEG10476.1 - 5.3 8.1 6.0 0.5 11.3 1.0 2.0 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain DnaJ PF00226.31 KEG10477.1 - 4.2e-14 52.4 0.0 2.1e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain TraG_N PF07916.11 KEG10478.1 - 0.031 13.1 2.4 0.066 12.1 2.4 1.6 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TLC PF03219.14 KEG10478.1 - 0.092 11.4 0.1 0.092 11.4 0.1 2.2 2 0 0 2 2 2 0 TLC ATP/ADP transporter T2SSM PF04612.12 KEG10478.1 - 0.16 12.0 1.7 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Clathrin_lg_ch PF01086.17 KEG10479.1 - 8.6e-06 26.0 14.2 1.6e-05 25.1 14.2 1.4 1 1 0 1 1 1 1 Clathrin light chain Creatininase PF02633.14 KEG10479.1 - 0.4 10.1 5.9 0.089 12.2 1.8 1.9 1 1 1 2 2 2 0 Creatinine amidohydrolase SNARE PF05739.19 KEG10480.1 - 1.7e-12 47.2 3.5 1.7e-12 47.2 3.5 2.9 3 1 0 3 3 3 1 SNARE domain DUF4383 PF14325.6 KEG10480.1 - 0.0062 16.8 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) Synaptobrevin PF00957.21 KEG10480.1 - 0.008 15.9 0.2 0.016 15.0 0.2 1.7 1 0 0 1 1 1 1 Synaptobrevin DUF2116 PF09889.9 KEG10480.1 - 0.019 14.9 1.0 0.055 13.4 1.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TMEM154 PF15102.6 KEG10480.1 - 0.056 13.3 1.1 0.076 12.9 0.3 1.7 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.6 KEG10480.1 - 0.14 12.4 0.6 0.28 11.4 0.6 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 KEG10480.1 - 0.25 11.6 1.6 0.28 11.5 0.3 1.8 2 0 0 2 2 2 0 Orf78 (ac78) SP_C-Propep PF08999.10 KEG10480.1 - 0.66 9.8 4.6 0.55 10.0 2.6 1.9 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Fez1 PF06818.15 KEG10480.1 - 2 8.8 8.2 2 8.8 0.3 2.5 1 1 1 2 2 2 0 Fez1 DUF3357 PF11837.8 KEG10480.1 - 2.3 8.7 5.1 4 8.0 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) UPF0258 PF06789.12 KEG10480.1 - 7.1 6.7 5.9 15 5.7 5.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Pkinase PF00069.25 KEG10481.1 - 3.5e-52 177.4 0.0 6.2e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10481.1 - 7.3e-26 91.0 0.0 1.5e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 KEG10481.1 - 6.8e-17 61.2 0.9 1.4e-16 60.2 0.9 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 KEG10481.1 - 1.6e-05 24.4 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Myb_Cef PF11831.8 KEG10481.1 - 3.1 7.3 0.0 3.1 7.3 0.0 3.7 4 1 0 4 4 4 0 pre-mRNA splicing factor component Pkinase PF00069.25 KEG10482.1 - 6e-57 193.0 0.0 6.8e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10482.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG10482.1 - 0.00021 20.2 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M24 PF00557.24 KEG10483.1 - 5.3e-29 101.4 0.6 8.3e-29 100.8 0.5 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 nsp8 PF08717.10 KEG10483.1 - 0.0012 18.7 0.1 0.0025 17.7 0.1 1.5 1 0 0 1 1 1 1 nsp8 replicase Pkinase PF00069.25 KEG10485.1 - 4.2e-72 242.7 0.0 4.9e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10485.1 - 1.2e-31 109.9 0.0 8e-31 107.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG10485.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBF1 PF08523.10 KEG10486.1 - 1e-11 45.1 1.7 1e-11 45.1 1.7 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KEG10486.1 - 1.2e-11 44.4 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEG10486.1 - 1.3e-06 28.6 0.8 2.4e-06 27.8 0.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEG10486.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KEG10486.1 - 0.013 15.4 0.2 0.026 14.5 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KEG10486.1 - 0.025 15.2 0.3 0.15 12.7 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain MIB_HERC2 PF06701.13 KEG10486.1 - 0.029 14.6 0.7 3.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Mib_herc2 HTH_25 PF13413.6 KEG10486.1 - 0.032 14.1 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain SecY PF00344.20 KEG10487.1 - 1e-53 182.6 5.2 1.4e-53 182.1 5.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KEG10487.1 - 2e-15 56.3 0.0 4.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p RRM_1 PF00076.22 KEG10488.1 - 0.0077 16.0 0.0 2.8 7.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAT PF16073.5 KEG10490.1 - 9.8e-06 25.5 1.0 3.6e-05 23.6 0.2 2.4 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KEG10490.1 - 0.031 14.6 0.0 0.088 13.2 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Exo_endo_phos PF03372.23 KEG10491.1 - 0.00048 19.7 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEP-utilizers_C PF02896.18 KEG10492.1 - 1.8e-90 303.0 0.0 2.8e-90 302.4 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 KEG10492.1 - 2.4e-74 250.5 0.0 4.3e-62 210.3 0.0 2.2 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KEG10492.1 - 3.1e-28 97.3 0.3 8.7e-28 95.9 0.3 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF3788 PF12663.7 KEG10492.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) HTH_24 PF13412.6 KEG10492.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding IQ PF00612.27 KEG10493.1 - 0.00025 20.6 0.9 0.00079 19.0 0.9 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AdoHcyase_NAD PF00670.21 KEG10493.1 - 0.092 12.8 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MqsA_antitoxin PF15731.5 KEG10494.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA FOP_dimer PF09398.10 KEG10496.1 - 3.1e-09 36.9 0.0 5.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KEG10496.1 - 5.5e-08 31.7 0.1 8.3e-08 31.1 0.1 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 KEG10496.1 - 0.026 14.5 0.4 0.063 13.3 0.4 1.6 1 0 0 1 1 1 0 LisH Snf7 PF03357.21 KEG10497.1 - 3.6e-12 46.2 14.5 4.7e-12 45.8 14.5 1.3 1 1 0 1 1 1 1 Snf7 DUF3947 PF13135.6 KEG10497.1 - 0.26 11.5 1.9 0.46 10.7 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3947) DUF3365 PF11845.8 KEG10497.1 - 0.63 10.4 3.3 0.97 9.7 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) Cytochrom_B562 PF07361.11 KEG10497.1 - 0.9 10.2 14.9 65 4.3 0.0 4.2 2 1 1 3 3 3 0 Cytochrome b562 CAF1C_H4-bd PF12265.8 KEG10498.1 - 5.9e-11 42.5 0.1 1.2e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KEG10498.1 - 0.14 13.0 0.1 0.14 13.0 0.1 4.6 4 1 0 4 4 4 0 WD domain, G-beta repeat Pho88 PF10032.9 KEG10499.1 - 1.7e-30 105.6 0.0 2e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) c-SKI_SMAD_bind PF08782.10 KEG10499.1 - 0.038 14.2 0.3 3.5 7.9 0.4 2.1 1 1 1 2 2 2 0 c-SKI Smad4 binding domain She9_MDM33 PF05546.11 KEG10501.1 - 0.043 13.6 0.2 0.047 13.5 0.2 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family K_channel_TID PF07941.11 KEG10503.1 - 0.12 12.8 7.1 0.16 12.4 7.1 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.25 KEG10504.1 - 5.8e-60 202.9 0.0 7.8e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10504.1 - 2.1e-27 96.0 0.0 2.7e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG10504.1 - 3e-06 27.3 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG10504.1 - 0.00011 21.6 0.0 0.00045 19.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEG10504.1 - 0.0012 17.7 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG10504.1 - 0.0017 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEG10504.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 KEG10504.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KEG10504.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 D123 PF07065.14 KEG10505.1 - 3.8e-09 36.2 0.0 1.7e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 D123 DUF3584 PF12128.8 KEG10506.1 - 0.0015 16.2 36.6 0.0026 15.4 36.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3552 PF12072.8 KEG10506.1 - 6.2 6.2 43.0 0.52 9.7 18.3 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF3552) GRIM-19 PF06212.12 KEG10507.1 - 2.4e-10 40.5 0.3 3.2e-10 40.1 0.3 1.2 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.6 KEG10508.1 - 1.5e-60 203.8 1.0 1.7e-60 203.7 1.0 1.0 1 0 0 1 1 1 1 DPCD protein family RNA_pol_L_2 PF13656.6 KEG10509.1 - 9.3e-26 89.4 0.1 1.3e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KEG10509.1 - 4.9e-06 25.9 0.0 8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sua5_yciO_yrdC PF01300.18 KEG10510.1 - 2.7e-49 167.1 0.0 4.1e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KEG10510.1 - 3e-10 40.8 0.0 4.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.29 KEG10511.1 - 1.3e-44 152.0 0.0 2.4e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG10511.1 - 1.6e-29 102.5 0.1 1.7e-28 99.2 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG10511.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEG10511.1 - 0.00098 18.4 0.1 0.0015 17.8 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase T4SS-DNA_transf PF02534.14 KEG10511.1 - 0.0028 16.5 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer CEP76-C2 PF15627.6 KEG10512.1 - 3.8e-38 130.5 0.0 6.3e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain UPF0220 PF05255.11 KEG10513.1 - 1.3e-13 50.9 1.8 1.4e-13 50.8 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) FxsA PF04186.13 KEG10513.1 - 0.011 15.9 2.3 0.017 15.2 0.3 2.1 2 1 0 2 2 2 0 FxsA cytoplasmic membrane protein DUF4131 PF13567.6 KEG10513.1 - 0.064 12.9 3.5 0.21 11.2 3.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4231 PF14015.6 KEG10513.1 - 0.15 12.6 0.3 0.35 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF202 PF02656.15 KEG10513.1 - 2.1 8.8 7.7 64 4.1 7.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) GDPD PF03009.17 KEG10514.1 - 8.8e-19 68.2 0.0 2.4e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Ax_dynein_light PF10211.9 KEG10516.1 - 7.9e-81 270.5 13.4 1e-80 270.1 13.4 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Spc24 PF08286.11 KEG10516.1 - 0.011 16.0 5.3 0.011 16.0 5.3 1.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.9 KEG10516.1 - 0.019 15.0 13.0 0.019 15.0 13.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rota_NSP3 PF01665.16 KEG10516.1 - 0.02 14.0 1.6 0.027 13.6 1.6 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Prefoldin PF02996.17 KEG10516.1 - 0.068 13.1 6.5 5.5 6.9 3.2 2.7 1 1 1 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KEG10516.1 - 0.15 12.6 5.1 0.35 11.5 5.1 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal GP41 PF00517.17 KEG10516.1 - 0.17 11.8 2.1 3.4 7.5 0.3 2.2 2 0 0 2 2 2 0 Retroviral envelope protein FlaC_arch PF05377.11 KEG10516.1 - 0.19 12.1 2.1 0.56 10.7 2.1 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KEG10516.1 - 0.21 10.1 2.7 0.3 9.6 2.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A End3 PF12761.7 KEG10516.1 - 0.38 10.9 11.1 0.069 13.3 6.7 1.9 3 0 0 3 3 2 0 Actin cytoskeleton-regulatory complex protein END3 ERM PF00769.19 KEG10516.1 - 0.39 10.5 18.8 0.069 13.0 15.4 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PilJ PF13675.6 KEG10516.1 - 0.48 10.5 4.4 0.3 11.1 2.3 1.9 2 1 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cnn_1N PF07989.11 KEG10516.1 - 0.7 10.1 14.9 0.16 12.1 8.5 2.8 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 KEG10516.1 - 1.1 9.8 24.3 5.3 7.6 23.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region L_lactis_ph-MCP PF06673.11 KEG10516.1 - 1.2 8.0 5.0 2.1 7.2 5.0 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF4337 PF14235.6 KEG10516.1 - 1.6 8.8 6.2 2.7 8.1 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) OmpH PF03938.14 KEG10516.1 - 2.9 8.2 12.0 1.4 9.2 8.9 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KEG10516.1 - 3.3 7.6 11.1 5.4 6.8 8.2 2.5 2 1 0 2 2 2 0 Septum formation initiator TolA_bind_tri PF16331.5 KEG10516.1 - 4.5 7.4 14.5 0.77 9.9 10.3 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Nsp1_C PF05064.13 KEG10516.1 - 7.3 6.4 11.5 3.4 7.5 8.2 2.1 2 1 2 4 4 4 0 Nsp1-like C-terminal region DUF4192 PF13830.6 KEG10516.1 - 8.3 6.4 10.0 15 5.6 10.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) DUF5320 PF17253.2 KEG10516.1 - 8.5 7.5 6.5 15 6.7 4.7 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) TIM PF00121.18 KEG10517.1 - 2.6e-88 295.5 0.0 2.9e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MEDS PF14417.6 KEG10517.1 - 0.15 11.9 0.2 1.7 8.4 0.2 2.3 1 1 1 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain EMP24_GP25L PF01105.24 KEG10519.1 - 1.7e-13 50.9 0.0 2.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BclA_C PF18573.1 KEG10519.1 - 0.015 15.2 0.0 0.91 9.4 0.0 2.2 1 1 1 2 2 2 0 BclA C-terminal domain TMEM220 PF15071.6 KEG10519.1 - 0.019 15.7 0.5 0.11 13.3 0.2 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix Man-6-P_recep PF02157.15 KEG10520.1 - 0.2 10.7 0.2 0.27 10.3 0.2 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DNA_pol_A PF00476.20 KEG10521.1 - 4.2e-49 167.6 0.0 6.4e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF3275 PF11679.8 KEG10521.1 - 0.6 10.1 4.4 0.16 11.9 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) BRICHOS PF04089.14 KEG10522.1 - 0.17 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 BRICHOS domain MCM PF00493.23 KEG10523.1 - 1.3e-88 295.9 0.0 2e-88 295.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEG10523.1 - 3.1e-34 117.5 0.3 5.5e-34 116.7 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEG10523.1 - 1.5e-22 79.8 0.6 1.5e-22 79.8 0.6 2.6 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 KEG10523.1 - 3e-10 40.6 0.0 9.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEG10523.1 - 6.6e-07 28.9 0.0 6.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEG10523.1 - 0.00045 20.2 0.0 0.0029 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEG10523.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PUA PF01472.20 KEG10523.1 - 0.027 14.4 2.2 3.5 7.7 0.2 2.5 2 0 0 2 2 2 0 PUA domain Sigma54_activat PF00158.26 KEG10523.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Methyltransf_25 PF13649.6 KEG10524.1 - 0.00016 22.3 0.1 0.00038 21.1 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEG10524.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KEG10524.1 - 0.014 15.2 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KEG10524.1 - 0.021 15.5 0.1 0.045 14.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEG10524.1 - 0.022 15.5 1.7 0.1 13.3 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain PQQ_3 PF13570.6 KEG10524.1 - 0.058 13.9 1.0 1.8 9.2 0.5 2.5 2 0 0 2 2 2 0 PQQ-like domain Mito_carr PF00153.27 KEG10525.1 - 8.9e-21 73.6 0.1 1.1e-20 73.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 KEG10526.1 - 1.1e-29 102.2 0.3 6.3e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Dishevelled PF02377.15 KEG10527.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Dishevelled specific domain DSPc PF00782.20 KEG10528.1 - 3.5e-09 36.6 0.0 7e-09 35.6 0.0 1.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG10528.1 - 4.8e-05 23.0 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KEG10528.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 KEG10529.1 - 2.3e-07 30.7 0.0 4.3e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG10529.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 KEG10530.1 - 0.073 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FHA PF00498.26 KEG10531.1 - 2.3e-13 50.2 0.0 5.4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Mucin PF01456.17 KEG10532.1 - 0.0011 19.0 11.9 0.036 14.1 6.2 2.5 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF2009 PF09418.10 KEG10532.1 - 0.0015 17.7 5.0 0.0022 17.1 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Sec34 PF04136.15 KEG10532.1 - 0.11 12.4 3.2 0.43 10.4 1.2 2.4 2 1 0 2 2 2 0 Sec34-like family T3SchapCesA PF11439.8 KEG10532.1 - 0.49 10.6 9.4 0.045 13.9 3.1 2.4 2 1 2 4 4 4 0 Type III secretion system filament chaperone CesA DUF1664 PF07889.12 KEG10532.1 - 2.1 8.4 10.5 3 7.9 3.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Flu_M1_C PF08289.11 KEG10532.1 - 7.4 6.9 8.2 1.1 9.5 0.3 3.1 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain Laminin_II PF06009.12 KEG10532.1 - 8.4 6.4 20.5 5.1 7.1 1.3 3.4 1 1 1 3 3 3 0 Laminin Domain II DUF948 PF06103.11 KEG10532.1 - 9.4 6.6 13.6 23 5.3 2.9 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) UCH PF00443.29 KEG10535.1 - 1.2e-55 188.8 0.1 2.2e-55 187.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG10535.1 - 1.2e-09 38.2 0.6 3.3e-09 36.8 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Prok-RING_4 PF14447.6 KEG10535.1 - 0.037 13.9 3.7 3 7.8 0.3 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Sgf11 PF08209.11 KEG10535.1 - 0.058 13.0 2.2 0.2 11.3 0.2 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-RING_5 PF14634.6 KEG10535.1 - 0.47 10.5 3.0 13 5.8 0.1 2.7 2 0 0 2 2 2 0 zinc-RING finger domain DUF5323 PF17257.2 KEG10536.1 - 0.0082 16.0 1.6 1.3 8.9 0.1 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5323) SNAPc19 PF15497.6 KEG10536.1 - 0.3 11.6 2.9 0.33 11.4 0.2 2.3 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Ribonucleas_3_3 PF14622.6 KEG10537.1 - 1e-07 32.1 0.2 1e-06 28.9 0.2 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like Raptor_N PF14538.6 KEG10537.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Ribonuclease_3 PF00636.26 KEG10537.1 - 0.099 13.3 0.0 0.24 12.1 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease III domain aGPT-Pplase1 PF18723.1 KEG10537.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 LRR_6 PF13516.6 KEG10538.1 - 2e-19 67.9 12.1 0.015 15.3 0.2 9.1 9 0 0 9 9 9 8 Leucine Rich repeat LRR_1 PF00560.33 KEG10538.1 - 4.6e-05 23.4 4.1 25 6.0 0.0 7.3 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 KEG10538.1 - 0.0014 18.4 5.7 5.4 6.9 0.0 5.3 4 2 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KEG10538.1 - 0.22 12.0 16.4 1.2 9.7 0.3 5.6 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) KAP PF05804.12 KEG10539.1 - 0.075 11.2 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Helicase_C PF00271.31 KEG10540.1 - 1e-06 29.0 0.1 3.3e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCCH_4 PF18044.1 KEG10540.1 - 3.1e-06 26.9 6.3 5e-06 26.2 6.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KEG10540.1 - 0.0001 22.1 5.9 0.0002 21.1 5.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) KH_1 PF00013.29 KEG10540.1 - 0.00042 20.1 0.0 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 KH domain zf_CCCH_4 PF18345.1 KEG10540.1 - 0.0013 18.7 7.7 0.003 17.6 7.7 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KEG10540.1 - 0.051 14.3 0.4 0.12 13.0 0.4 1.6 1 0 0 1 1 1 0 Torus domain Ribosomal_S13 PF00416.22 KEG10540.1 - 0.073 13.5 1.3 0.22 11.9 0.3 2.2 2 0 0 2 2 2 0 Ribosomal protein S13/S18 zf-CCCH_3 PF15663.5 KEG10540.1 - 0.96 9.7 4.2 0.93 9.7 0.9 2.6 3 0 0 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEG10540.1 - 4.7 7.8 6.7 9.2 6.9 6.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger tRNA-synt_1d PF00750.19 KEG10541.1 - 2.3e-110 368.8 0.1 1e-65 222.0 0.0 2.8 1 1 2 3 3 3 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KEG10541.1 - 5.1e-24 84.7 0.4 1.9e-22 79.7 0.0 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KEG10541.1 - 2.9e-14 53.4 0.5 1.1e-13 51.6 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 KEG10541.1 - 0.028 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Cupin_8 PF13621.6 KEG10542.1 - 8.4e-16 58.4 0.1 7.7e-15 55.3 0.0 2.5 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 KEG10542.1 - 2.9e-09 37.3 0.1 5.9e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.33 KEG10542.1 - 3.4e-05 23.6 0.4 8.3e-05 22.4 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEG10542.1 - 9.1e-05 22.3 1.3 0.00022 21.1 1.3 1.6 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 KEG10542.1 - 0.0008 19.0 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KEG10542.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain HAUS6_N PF14661.6 KEG10542.1 - 0.078 12.6 0.6 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cupin_1 PF00190.22 KEG10542.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Cupin Mo25 PF08569.11 KEG10543.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Mo25-like zf-C4H2 PF10146.9 KEG10544.1 - 0.12 12.7 4.1 6.6 7.0 1.3 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Ecotin PF03974.13 KEG10546.1 - 4e-41 139.9 0.0 4.7e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Ecotin AAA PF00004.29 KEG10547.1 - 8.2e-38 129.8 0.0 1.6e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG10547.1 - 1.1e-12 47.6 0.2 1.1e-12 47.6 0.2 2.4 2 1 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 KEG10547.1 - 3.1e-10 39.9 0.0 1.8e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 KEG10547.1 - 5.7e-06 26.4 0.1 2.8e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG10547.1 - 7.4e-06 25.8 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG10547.1 - 0.00017 21.9 0.1 0.0032 17.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KEG10547.1 - 0.00079 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KEG10547.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEG10547.1 - 0.0041 17.5 5.9 0.016 15.6 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain Mg_chelatase PF01078.21 KEG10547.1 - 0.0046 16.4 0.1 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEG10547.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KEG10547.1 - 0.023 15.3 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEG10547.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KEG10547.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KEG10547.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 KEG10547.1 - 0.073 13.2 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEG10547.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEG10547.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEG10547.1 - 0.16 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KEG10547.1 - 0.17 11.3 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein FXMRP1_C_core PF12235.8 KEG10550.1 - 0.022 15.4 0.7 0.041 14.5 0.7 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal zf-ISL3 PF14690.6 KEG10550.1 - 0.13 13.0 0.8 0.13 13.0 0.8 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Cript PF10235.9 KEG10550.1 - 0.38 11.4 16.5 0.19 12.3 2.1 4.3 4 1 1 5 5 5 0 Microtubule-associated protein CRIPT DUF1289 PF06945.13 KEG10550.1 - 1.1 9.1 6.9 8.3 6.3 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1289) RRM_1 PF00076.22 KEG10551.1 - 6.3e-22 77.2 0.0 3.6e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KEG10551.1 - 0.00028 20.9 1.1 0.0062 16.6 0.3 2.7 2 1 0 2 2 2 1 Limkain b1 RRM_5 PF13893.6 KEG10551.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG10551.1 - 0.11 12.4 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ribosomal_L44 PF00935.19 KEG10552.1 - 1.7e-32 111.7 8.0 2.4e-32 111.2 8.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 zinc_ribbon_12 PF11331.8 KEG10552.1 - 0.022 14.6 0.5 0.054 13.3 0.5 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain Spore_coat_CotO PF14153.6 KEG10553.1 - 1.9 8.4 11.4 2.5 8.0 11.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF5486 PF17588.2 KEG10554.1 - 6.8 6.7 7.4 1.4 8.8 3.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5486) ABC_tran PF00005.27 KEG10555.1 - 3.1e-23 82.8 0.0 7.3e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEG10555.1 - 0.00038 20.0 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KEG10555.1 - 0.01 16.4 0.1 0.11 13.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KEG10555.1 - 0.01 16.2 0.1 0.04 14.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KEG10555.1 - 0.13 12.6 0.3 0.65 10.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KEG10555.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KEG10555.1 - 0.17 11.5 0.0 0.61 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RBB1NT PF08169.11 KEG10556.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Adaptin_binding PF10199.9 KEG10557.1 - 7.9e-11 42.6 0.5 8.3e-05 23.2 0.4 3.7 3 2 0 3 3 3 3 Alpha and gamma adaptin binding protein p34 HTH_Tnp_Tc5 PF03221.16 KEG10557.1 - 0.083 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain RNA_pol PF00940.19 KEG10559.1 - 2.4e-131 438.4 0.0 3.7e-131 437.8 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase fn3 PF00041.21 KEG10560.1 - 3.8e-16 59.2 0.2 7.9e-06 26.1 0.0 5.3 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KEG10560.1 - 0.0071 16.9 0.0 3.6 8.2 0.0 3.4 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain EF-hand_8 PF13833.6 KEG10561.1 - 9.3e-05 22.2 0.0 0.0037 17.1 0.0 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG10561.1 - 0.00043 19.6 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KEG10561.1 - 0.0013 18.5 0.0 0.37 10.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KEG10561.1 - 0.0067 16.9 0.1 22 5.6 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair Cys_rich_VLP PF14194.6 KEG10561.1 - 0.21 11.7 0.6 8.8 6.5 0.0 2.1 1 1 1 2 2 2 0 Cysteine-rich VLP Peptidase_S9 PF00326.21 KEG10562.1 - 0.00017 21.2 0.2 0.014 14.9 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEG10562.1 - 0.0025 17.6 0.1 0.0075 16.1 0.1 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KEG10562.1 - 0.0066 16.1 0.0 0.007 16.0 0.0 1.4 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KEG10562.1 - 0.013 15.1 0.3 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KEG10562.1 - 0.017 14.6 0.2 0.028 13.9 0.2 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase RL10P_insert PF17777.1 KEG10563.1 - 1.3e-24 86.0 0.0 2.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KEG10563.1 - 5.2e-20 71.4 0.0 7.3e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3577 PF12101.8 KEG10563.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) VPS9 PF02204.18 KEG10564.1 - 4.7e-34 116.7 0.0 8.1e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HALZ PF02183.18 KEG10565.1 - 0.00026 21.1 2.0 0.00036 20.7 0.4 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper ZapB PF06005.12 KEG10565.1 - 0.00094 19.6 12.1 0.18 12.2 12.1 2.8 1 1 0 1 1 1 1 Cell division protein ZapB Golgin_A5 PF09787.9 KEG10565.1 - 0.0051 16.3 10.6 0.007 15.9 10.6 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 KEG10565.1 - 0.0082 16.1 8.3 0.042 13.9 3.5 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 KEG10565.1 - 0.017 15.2 10.3 0.075 13.1 10.3 1.9 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KEG10565.1 - 0.031 14.5 5.3 0.038 14.2 5.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KEG10565.1 - 0.046 14.1 1.9 4.3 7.8 0.3 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KEG10565.1 - 0.08 12.2 11.5 0.095 12.0 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 KEG10565.1 - 0.097 13.1 9.8 0.12 12.9 9.8 1.2 1 0 0 1 1 1 0 Fez1 CCDC-167 PF15188.6 KEG10565.1 - 0.11 12.8 9.2 1.2 9.5 9.2 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 TolA_bind_tri PF16331.5 KEG10565.1 - 0.2 11.8 16.4 2 8.6 9.5 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation MutS_III PF05192.18 KEG10565.1 - 0.25 11.5 4.4 0.3 11.3 4.4 1.0 1 0 0 1 1 1 0 MutS domain III YabA PF06156.13 KEG10565.1 - 0.34 11.6 9.2 0.62 10.7 4.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4140 PF13600.6 KEG10565.1 - 0.38 11.2 11.0 0.54 10.7 3.1 2.3 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GIT_CC PF16559.5 KEG10565.1 - 0.46 10.4 7.1 0.43 10.5 1.9 2.7 1 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Sipho_Gp157 PF05565.11 KEG10565.1 - 0.52 10.3 9.1 1.9 8.5 2.6 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 Atg14 PF10186.9 KEG10565.1 - 0.68 9.0 11.5 1.1 8.3 11.5 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KEG10565.1 - 0.68 10.6 14.8 1.1 10.0 0.5 3.0 1 1 2 3 3 3 0 SlyX DUF1664 PF07889.12 KEG10565.1 - 0.75 9.9 3.8 1 9.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 KEG10565.1 - 0.78 10.1 11.3 1.2 9.5 10.2 1.9 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator APG6_N PF17675.1 KEG10565.1 - 0.82 10.2 14.0 1.5 9.3 14.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4051 PF13260.6 KEG10565.1 - 1.7 8.4 4.7 4.1 7.2 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4051) XhlA PF10779.9 KEG10565.1 - 1.7 8.9 8.0 12 6.2 3.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 KEG10565.1 - 2 8.2 12.4 0.58 10.0 4.5 2.8 1 1 1 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KEG10565.1 - 2.7 6.8 12.3 3.5 6.4 12.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EF-1_beta_acid PF10587.9 KEG10565.1 - 2.7 8.5 7.0 3.3 8.2 1.0 3.0 1 1 1 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Metal_resist PF13801.6 KEG10565.1 - 2.9 8.1 12.3 8 6.7 12.3 1.8 1 1 0 1 1 1 0 Heavy-metal resistance DUF2381 PF09544.10 KEG10565.1 - 3.1 7.2 9.3 0.81 9.2 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) TMPIT PF07851.13 KEG10565.1 - 3.5 6.8 6.7 1.2 8.3 2.3 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 KEG10565.1 - 4.9 6.4 9.7 6.3 6.1 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_6 PF12697.7 KEG10567.1 - 1.7e-06 28.8 9.3 4.5e-05 24.2 3.0 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEG10567.1 - 2.9e-06 27.1 0.1 0.00023 20.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold WD40 PF00400.32 KEG10568.1 - 2e-09 37.9 0.3 0.42 11.6 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG10568.1 - 5.9e-05 23.3 0.0 0.44 10.9 0.0 3.9 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 KEG10568.1 - 0.064 11.5 26.4 0.092 11.0 26.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 KEG10568.1 - 2 7.8 13.7 3.5 7.0 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4604 PF15377.6 KEG10568.1 - 2 8.8 30.3 1.9 8.9 26.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Cwf_Cwc_15 PF04889.12 KEG10568.1 - 2.2 7.9 27.9 5.2 6.7 27.9 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KEG10568.1 - 3.2 7.0 24.8 5.3 6.3 24.8 1.3 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.7 KEG10568.1 - 5.7 4.9 13.6 8.3 4.4 13.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_L1 PF00687.21 KEG10569.1 - 0.034 13.9 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family Mito_carr PF00153.27 KEG10570.1 - 1.2e-07 31.5 2.6 0.00037 20.4 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Dynein_AAA_lid PF17852.1 KEG10570.1 - 0.19 11.8 0.1 0.76 9.9 0.0 1.9 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain Arf PF00025.21 KEG10572.1 - 6.3e-64 214.6 0.0 7.1e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KEG10572.1 - 1.7e-14 53.8 0.7 8.7e-09 35.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KEG10572.1 - 4.2e-12 46.4 0.0 5.7e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEG10572.1 - 1.1e-09 38.1 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEG10572.1 - 1.3e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEG10572.1 - 3.5e-08 33.1 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEG10572.1 - 8.2e-06 25.9 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG10572.1 - 0.00019 21.0 0.0 0.00055 19.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KEG10572.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 KEG10572.1 - 0.041 13.5 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LMBR1 PF04791.16 KEG10573.1 - 4.6e-37 128.1 34.5 9.7e-28 97.3 6.8 2.1 1 1 0 2 2 2 2 LMBR1-like membrane protein Clat_adaptor_s PF01217.20 KEG10574.1 - 2.6e-10 40.4 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 KEG10574.1 - 0.00017 21.6 0.1 0.00021 21.3 0.1 1.2 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 UCR_14kD PF02271.16 KEG10575.1 - 5.8e-08 32.6 0.1 2.3e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit TrkH PF02386.16 KEG10577.1 - 2.2e-12 46.2 18.4 1.7e-09 36.7 2.3 3.3 3 1 0 3 3 3 3 Cation transport protein Band_7 PF01145.25 KEG10578.1 - 2.9e-23 82.8 1.1 4.3e-23 82.2 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Transket_pyr PF02779.24 KEG10581.1 - 2.3e-43 147.9 0.0 3.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEG10581.1 - 1e-35 122.3 0.0 3.6e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KEG10581.1 - 0.00024 21.4 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Pkinase PF00069.25 KEG10583.1 - 6.9e-65 219.0 0.0 8.4e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10583.1 - 1e-31 110.2 0.1 1.6e-31 109.5 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEG10583.1 - 1.2e-06 28.0 0.6 2.3e-06 27.1 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEG10583.1 - 1.1e-05 24.6 1.5 1.7e-05 24.0 1.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KEG10583.1 - 0.00028 20.3 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG10583.1 - 0.0034 16.2 0.2 0.0072 15.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KEG10583.1 - 0.012 15.2 0.3 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KEG10583.1 - 0.045 13.7 0.2 0.69 9.8 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KEG10585.1 - 1.2e-54 185.4 0.0 2.8e-49 167.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10585.1 - 3.5e-30 105.1 0.0 5.7e-29 101.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEG10585.1 - 9.9e-14 51.5 0.2 6e-13 48.9 0.2 2.3 1 1 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KEG10585.1 - 1.3e-11 44.3 0.0 8.2e-08 31.9 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 KEG10585.1 - 5e-06 26.7 0.1 2.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 KEG10585.1 - 0.083 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family DUF4333 PF14230.6 KEG10585.1 - 0.18 12.1 0.2 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4333) Aa_trans PF01490.18 KEG10586.1 - 1.1e-41 142.9 11.9 1.4e-41 142.5 11.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG10586.1 - 5.7e-07 28.9 14.2 1.1e-06 28.0 14.2 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family F-box-like PF12937.7 KEG10587.1 - 0.00037 20.3 0.1 0.0011 18.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Tmemb_185A PF10269.9 KEG10587.1 - 0.0043 16.8 9.4 0.0043 16.8 9.4 1.8 2 0 0 2 2 2 1 Transmembrane Fragile-X-F protein F-box PF00646.33 KEG10587.1 - 0.0054 16.6 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF1738 PF08401.11 KEG10589.1 - 3e-05 24.1 0.0 0.0003 20.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) Mrr_cat PF04471.12 KEG10589.1 - 0.012 15.6 0.0 0.037 14.0 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease TTL PF03133.15 KEG10590.1 - 1.1e-45 156.0 0.0 1e-44 152.9 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG10590.1 - 7.7e-05 22.1 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp TM1506 PF08973.10 KEG10590.1 - 0.049 13.3 0.0 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) PQQ_2 PF13360.6 KEG10592.1 - 0.00025 20.7 0.8 0.04 13.5 0.1 3.1 3 1 0 3 3 3 1 PQQ-like domain VCBS PF13517.6 KEG10592.1 - 0.0063 17.1 0.3 0.16 12.6 0.2 2.9 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KEG10592.1 - 0.085 13.0 0.7 0.27 11.4 0.7 1.8 1 0 0 1 1 1 0 FG-GAP repeat BBS2_C PF14782.6 KEG10592.1 - 0.096 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Trp_ring PF18669.1 KEG10592.1 - 0.25 11.6 1.6 0.79 9.9 0.1 2.4 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain UCH PF00443.29 KEG10593.1 - 1.9e-52 178.3 0.2 3.4e-52 177.5 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG10593.1 - 5.3e-09 36.1 9.7 5.6e-05 22.9 0.1 3.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CDC45 PF02724.14 KEG10593.1 - 0.002 16.5 7.1 0.0033 15.8 7.1 1.2 1 0 0 1 1 1 1 CDC45-like protein DUSP PF06337.12 KEG10593.1 - 0.0076 16.9 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Pex16 PF08610.10 KEG10593.1 - 0.049 12.8 0.2 0.092 11.9 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SAPS PF04499.15 KEG10593.1 - 0.07 11.9 1.0 0.12 11.2 1.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.17 KEG10593.1 - 0.15 12.2 0.6 0.3 11.2 0.6 1.4 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 KEG10593.1 - 0.3 10.7 6.8 0.57 9.8 6.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF4746 PF15928.5 KEG10593.1 - 0.31 10.4 13.1 0.62 9.4 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sec62 PF03839.16 KEG10593.1 - 0.54 9.7 6.8 0.99 8.9 6.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Cytomega_UL84 PF06284.11 KEG10593.1 - 0.56 8.6 3.2 0.92 7.9 3.2 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4407 PF14362.6 KEG10593.1 - 0.9 8.8 4.0 1.6 8.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VIR_N PF15912.5 KEG10593.1 - 1.5 8.3 6.3 3.4 7.2 6.3 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal DUF913 PF06025.12 KEG10593.1 - 1.9 7.4 4.4 3.6 6.5 4.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 KEG10593.1 - 4.2 6.7 7.5 9.9 5.4 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 KEG10593.1 - 5.1 5.2 15.7 8.3 4.5 15.7 1.2 1 0 0 1 1 1 0 Nop14-like family Afi1 PF07792.12 KEG10593.1 - 7.4 7.1 9.4 19 5.8 9.4 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking USP8_interact PF08941.10 KEG10594.1 - 2.9 7.7 9.6 1.5 8.6 0.5 3.5 4 0 0 4 4 4 0 USP8 interacting Sec20 PF03908.13 KEG10594.1 - 3.7 7.5 13.6 2 8.4 2.8 4.0 3 1 0 3 3 3 0 Sec20 SNAP PF14938.6 KEG10595.1 - 6.7e-55 186.5 17.3 7.8e-55 186.3 17.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KEG10595.1 - 2.3e-07 30.5 5.8 3e-07 30.1 5.8 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 KEG10595.1 - 1.5e-06 28.5 7.8 0.0099 16.6 0.2 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG10595.1 - 2.1e-06 27.9 8.2 0.0016 18.7 1.2 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG10595.1 - 1.6e-05 25.4 5.9 0.02 15.4 0.7 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG10595.1 - 2.1e-05 24.2 12.2 0.035 14.1 0.1 5.6 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG10595.1 - 0.00073 20.0 11.2 0.68 10.7 0.0 5.7 5 3 1 6 6 6 2 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KEG10595.1 - 0.00083 19.0 3.0 0.0016 18.1 3.0 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 PPR PF01535.20 KEG10595.1 - 0.0063 16.7 0.1 9.1 6.8 0.0 3.3 2 0 0 2 2 2 1 PPR repeat TPR_8 PF13181.6 KEG10595.1 - 0.012 15.7 12.5 7.3 7.1 0.0 5.9 5 1 1 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KEG10595.1 - 0.13 11.9 9.5 0.2 11.3 3.3 3.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 KEG10595.1 - 0.14 12.3 20.0 2.9 8.2 0.1 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG10595.1 - 0.18 11.5 8.7 15 5.4 0.0 4.8 5 1 1 6 6 6 0 TPR repeat TPR_1 PF00515.28 KEG10595.1 - 3.7 7.5 10.8 22 5.1 0.8 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KEG10595.1 - 7.3 6.1 8.2 7.2 6.2 0.4 3.9 6 0 0 6 6 6 0 SHNi-TPR EF-hand_7 PF13499.6 KEG10597.1 - 0.00046 20.6 0.0 0.011 16.2 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG10597.1 - 0.0043 16.9 0.0 0.046 13.6 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG10597.1 - 0.0045 16.4 0.9 0.033 13.7 0.6 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KEG10597.1 - 0.0056 16.5 0.1 0.099 12.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain Ins145_P3_rec PF08709.11 KEG10597.1 - 0.057 12.6 0.0 0.39 9.9 0.0 2.2 2 1 1 3 3 3 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Pro_isomerase PF00160.21 KEG10598.1 - 2.4e-38 131.9 0.0 2.7e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 KEG10601.1 - 3.2e-22 78.8 0.0 5.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.7 KEG10601.1 - 0.24 11.4 0.6 0.46 10.5 0.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ATP11 PF06644.11 KEG10601.1 - 0.8 9.4 4.0 1.5 8.6 4.0 1.4 1 0 0 1 1 1 0 ATP11 protein SPX PF03105.19 KEG10601.1 - 6.9 6.5 11.2 9.8 6.0 11.2 1.2 1 0 0 1 1 1 0 SPX domain His_Phos_2 PF00328.22 KEG10602.1 - 2.3e-05 23.9 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TBCC PF07986.12 KEG10603.1 - 1.2e-26 92.8 2.9 2e-26 92.1 2.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 KEG10603.1 - 0.0029 17.2 0.6 0.0047 16.6 0.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Proteasom_PSMB PF10508.9 KEG10603.1 - 0.12 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit cobW PF02492.19 KEG10604.1 - 1.5e-46 158.2 0.1 1.9e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KEG10604.1 - 0.00052 20.0 0.2 0.88 9.4 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KEG10604.1 - 0.011 16.2 0.1 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 KEG10604.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.6 KEG10604.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KEG10604.1 - 0.034 13.9 0.1 0.065 13.0 0.1 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KEG10604.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 KEG10604.1 - 0.087 12.7 0.2 0.73 9.7 0.2 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KEG10604.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEG10604.1 - 0.1 13.0 0.1 0.86 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KEG10604.1 - 0.11 12.4 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KEG10604.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEG10604.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 KEG10606.1 - 8.9e-23 79.3 64.1 0.0012 18.8 1.9 9.9 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_2 PF13696.6 KEG10606.1 - 3.1e-05 23.7 3.1 0.00046 19.9 0.8 9.5 9 0 0 9 9 9 5 Zinc knuckle NYN PF01936.18 KEG10606.1 - 8.2e-05 23.1 0.0 0.00039 20.9 0.0 1.9 1 1 0 1 1 1 1 NYN domain zf-CCHC_4 PF14392.6 KEG10606.1 - 5.4 6.8 64.8 0.13 12.0 0.7 9.3 7 1 2 9 9 9 0 Zinc knuckle Topoisom_bac PF01131.20 KEG10607.1 - 2.6e-108 362.7 0.0 3.3e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KEG10607.1 - 2.2e-11 43.9 0.0 4.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.12 KEG10607.1 - 9.9e-08 32.0 1.5 3.3e-07 30.3 1.5 2.0 1 0 0 1 1 1 1 GRF zinc finger zf-C4_Topoisom PF01396.19 KEG10607.1 - 5.1e-05 23.0 0.1 5.1e-05 23.0 0.1 3.3 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Cullin_Nedd8 PF10557.9 KEG10607.1 - 0.029 14.4 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Cullin protein neddylation domain Vps53_N PF04100.12 KEG10609.1 - 0.0042 16.1 0.4 0.0042 16.1 0.4 2.6 2 1 0 3 3 3 1 Vps53-like, N-terminal Coleoptericin PF06286.11 KEG10610.1 - 0.0078 16.3 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 2 Coleoptericin 5-FTHF_cyc-lig PF01812.20 KEG10611.1 - 9.7e-19 67.9 0.1 3.2e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family Met_gamma_lyase PF06838.11 KEG10611.1 - 0.15 10.5 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase HIT PF01230.23 KEG10612.1 - 1.1e-11 45.3 0.3 2e-11 44.5 0.3 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEG10612.1 - 0.0016 18.9 0.1 0.0042 17.6 0.1 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LRR_4 PF12799.7 KEG10615.1 - 3.9e-14 52.5 6.0 0.29 11.6 0.0 7.8 7 2 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10615.1 - 0.11 12.2 13.6 3.8 7.4 0.2 6.4 4 2 1 6 6 6 0 Leucine rich repeat RRM_1 PF00076.22 KEG10616.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.24 KEG10617.1 - 3.8e-148 494.2 9.0 4.3e-148 494.0 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tetraspanin PF00335.20 KEG10618.1 - 4e-24 85.6 9.5 5.1e-24 85.3 9.5 1.1 1 0 0 1 1 1 1 Tetraspanin family SLC3A2_N PF16028.5 KEG10618.1 - 0.009 15.5 3.6 0.009 15.5 3.6 2.3 2 0 0 2 2 2 1 Solute carrier family 3 member 2 N-terminus Glucosamine_iso PF01182.20 KEG10619.1 - 1.6e-19 70.7 0.0 2.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FabA PF07977.13 KEG10619.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 FabA-like domain FAD_binding_8 PF08022.12 KEG10619.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Pkinase PF00069.25 KEG10620.1 - 2.1e-76 256.8 0.0 2.7e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10620.1 - 7.5e-40 136.8 0.0 3.5e-39 134.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10620.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEG10620.1 - 0.039 13.9 0.6 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG10620.1 - 0.056 12.4 0.1 0.092 11.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KEG10620.1 - 0.058 13.0 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KEG10620.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KEG10620.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family CXCR4_N PF12109.8 KEG10621.1 - 0.092 13.0 1.6 0.19 11.9 1.6 1.5 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal DA1-like PF12315.8 KEG10621.1 - 0.24 10.8 0.2 0.63 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein DA1 P_C PF06640.11 KEG10621.1 - 0.25 11.4 3.2 8.9 6.4 0.9 2.6 2 0 0 2 2 2 0 P protein C-terminus AAA_16 PF13191.6 KEG10622.1 - 0.00045 20.6 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KEG10622.1 - 0.0012 19.1 0.1 0.0047 17.1 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KEG10622.1 - 0.0012 18.4 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KEG10622.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.6 KEG10622.1 - 0.0022 18.4 0.1 0.004 17.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG10622.1 - 0.0034 17.7 0.0 0.0087 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 KEG10622.1 - 0.0038 16.3 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Arf PF00025.21 KEG10622.1 - 0.0047 16.4 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family TrwB_AAD_bind PF10412.9 KEG10622.1 - 0.0071 15.3 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KEG10622.1 - 0.011 15.8 0.4 0.023 14.8 0.4 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KEG10622.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KEG10622.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEG10622.1 - 0.019 14.5 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEG10622.1 - 0.03 14.7 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KEG10622.1 - 0.032 14.4 1.3 0.71 10.0 1.2 2.6 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KEG10622.1 - 0.034 13.7 0.2 0.054 13.0 0.2 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KEG10622.1 - 0.047 12.9 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FeoB_N PF02421.18 KEG10622.1 - 0.059 12.9 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Zeta_toxin PF06414.12 KEG10622.1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KEG10622.1 - 0.085 12.4 0.3 0.37 10.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KEG10622.1 - 0.1 11.7 0.0 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 KEG10622.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEG10622.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 KEG10622.1 - 0.12 12.0 0.3 0.38 10.3 0.2 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 KEG10622.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KEG10622.1 - 0.26 11.0 1.7 0.53 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain Baculo_11_kDa PF06143.11 KEG10624.1 - 0.15 11.6 0.5 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Dopey_N PF04118.14 KEG10626.1 - 7.2e-58 196.1 0.0 1.4e-57 195.2 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal Abhydrolase_1 PF00561.20 KEG10627.1 - 2.1e-09 37.4 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-MYND PF01753.18 KEG10628.1 - 2.6e-05 24.2 7.4 7.2e-05 22.8 7.4 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KEG10628.1 - 0.015 15.4 3.2 0.044 13.9 3.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RhoGAP PF00620.27 KEG10628.1 - 0.022 14.6 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 RhoGAP domain TruD PF01142.18 KEG10629.1 - 2.2e-37 128.9 0.0 8.2e-30 103.9 0.0 3.1 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) EMP70 PF02990.16 KEG10630.1 - 2.5e-145 485.1 0.9 3e-145 484.8 0.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF1129 PF06570.11 KEG10630.1 - 7.8 5.9 16.2 2.6 7.5 4.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) ATP-synt_ab PF00006.25 KEG10631.1 - 4.9e-106 353.1 0.0 7.8e-106 352.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KEG10631.1 - 3.3e-44 149.6 0.3 7.3e-44 148.5 0.1 1.7 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KEG10631.1 - 1.9e-20 73.1 9.3 1.8e-15 57.2 1.5 2.9 3 0 0 3 3 3 2 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L13 PF00572.18 KEG10632.1 - 1.7e-27 96.2 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.12 KEG10634.1 - 3.2e-24 86.0 0.0 5.5e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4085 PF13315.6 KEG10635.1 - 0.078 12.6 2.1 0.15 11.7 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) CDC73_N PF16050.5 KEG10635.1 - 0.55 9.5 9.4 0.4 10.0 8.3 1.3 1 1 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal DUF501 PF04417.12 KEG10636.1 - 1.4e-27 96.2 0.3 2.3e-27 95.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.21 KEG10638.1 - 1.5e-42 146.1 0.0 1.9e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1658 PF07871.11 KEG10639.1 - 0.16 12.0 1.9 0.51 10.4 1.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) WD40 PF00400.32 KEG10642.1 - 3.2e-17 62.6 5.5 0.0011 19.7 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG10642.1 - 0.053 13.8 0.0 17 5.8 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KEG10642.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 KEG10642.1 - 0.23 10.4 0.0 1.4 7.8 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CotH PF08757.11 KEG10643.1 - 1.4e-08 34.7 0.0 4.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 CotH kinase protein Beta_helix PF13229.6 KEG10643.1 - 0.0043 16.9 0.6 0.0078 16.1 0.6 1.4 1 0 0 1 1 1 1 Right handed beta helix region DUF591 PF04569.14 KEG10644.1 - 0.9 9.6 8.7 6.5 6.9 8.7 2.5 1 1 0 1 1 1 0 Protein of unknown function Macoilin PF09726.9 KEG10644.1 - 1.2 7.6 4.1 1.8 7.0 4.1 1.2 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 KEG10644.1 - 1.3 6.8 4.7 1.8 6.3 4.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 KEG10644.1 - 2.1 5.3 6.2 3.6 4.6 6.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MDFI PF15316.6 KEG10644.1 - 5.4 7.1 8.6 1.1 9.4 4.0 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Apt1 PF10351.9 KEG10644.1 - 9 5.0 6.8 14 4.4 6.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LELP1 PF15042.6 KEG10646.1 - 6.1 7.3 9.5 0.33 11.3 1.6 2.1 1 1 1 2 2 2 0 Late cornified envelope-like proline-rich protein 1 MORN PF02493.20 KEG10647.1 - 6.5e-09 35.2 6.2 0.0031 17.3 0.5 3.9 3 1 0 3 3 3 2 MORN repeat Atg8 PF02991.16 KEG10648.1 - 8.7e-28 96.6 0.0 9.9e-27 93.2 0.0 2.0 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEG10648.1 - 2.2e-06 28.0 0.0 3.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PriA_C PF18074.1 KEG10648.1 - 0.18 12.7 0.1 2.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain CHAP PF05257.16 KEG10649.1 - 4.5e-18 65.6 0.0 7.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 KEG10650.1 - 6.5e-07 29.8 0.1 1.8e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 CHAP domain Amidase_6 PF12671.7 KEG10650.1 - 0.036 14.2 0.3 0.12 12.5 0.3 1.9 1 1 0 1 1 1 0 Putative amidase domain Apc15p PF05841.11 KEG10653.1 - 0.49 11.2 1.9 0.99 10.2 1.9 1.4 1 0 0 1 1 1 0 Apc15p protein Glyco_transf_10 PF00852.19 KEG10654.1 - 4.7e-21 75.3 0.1 2.6e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term VPS38 PF17649.1 KEG10658.1 - 0.011 14.6 2.5 0.015 14.2 2.5 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF5344 PF17279.2 KEG10658.1 - 0.07 13.7 0.5 0.18 12.4 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) ADIP PF11559.8 KEG10658.1 - 0.1 12.7 2.6 0.21 11.6 2.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PET10 PF17316.2 KEG10658.1 - 0.16 11.5 1.3 0.25 10.9 1.3 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 HIP1_clath_bdg PF16515.5 KEG10658.1 - 1 10.0 7.8 0.43 11.2 3.7 2.2 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ras PF00071.22 KEG10659.1 - 1.8e-25 89.4 0.0 3.8e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEG10659.1 - 1.4e-18 67.2 0.0 5.6e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG10659.1 - 1.4e-07 31.1 0.0 1.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEG10659.1 - 5.2e-05 22.9 0.0 0.00027 20.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG10659.1 - 7.7e-05 22.7 0.0 0.00031 20.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.22 KEG10662.1 - 7.2e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pal1 PF08316.11 KEG10662.1 - 0.14 12.9 2.2 0.36 11.6 2.0 1.7 2 0 0 2 2 2 0 Pal1 cell morphology protein IBR PF01485.21 KEG10663.1 - 0.024 14.9 0.8 0.024 14.9 0.8 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MDD_C PF18376.1 KEG10664.1 - 1.4e-55 187.9 0.2 2.2e-55 187.3 0.2 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KEG10664.1 - 3.2e-06 27.3 4.5 7e-06 26.2 4.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain X PF00739.19 KEG10664.1 - 0.13 12.4 0.5 0.26 11.4 0.5 1.5 1 0 0 1 1 1 0 Trans-activation protein X RRM_1 PF00076.22 KEG10665.1 - 4.1e-06 26.5 0.0 0.0036 17.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MmlI PF09448.10 KEG10665.1 - 0.1 13.0 0.0 0.34 11.4 0.0 2.0 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase MFS_1 PF07690.16 KEG10666.1 - 1e-26 93.7 42.5 1e-26 93.7 42.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG10666.1 - 4.9e-13 48.7 16.8 4.9e-13 48.7 16.8 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KEG10666.1 - 4e-12 45.2 31.8 7.4e-05 21.2 5.4 4.2 3 2 2 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family PspB PF06667.12 KEG10666.1 - 4.9 7.3 7.0 5.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Phage shock protein B Cytochrom_C552 PF02335.15 KEG10667.1 - 0.047 12.6 0.7 0.23 10.3 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c552 T2SS_PulS_OutS PF09691.10 KEG10667.1 - 0.091 12.9 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) Antimicrobial14 PF08109.11 KEG10667.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Lactocin 705 family zf-C2HC_2 PF13913.6 KEG10669.1 - 6e-41 137.6 56.7 3.3e-10 39.6 0.9 7.9 9 0 0 9 9 9 6 zinc-finger of a C2HC-type DZR PF12773.7 KEG10669.1 - 1.4e-18 66.6 24.3 6.8e-12 45.2 9.1 8.5 6 3 1 7 7 7 3 Double zinc ribbon zinc_ribbon_2 PF13240.6 KEG10669.1 - 3.5e-05 23.4 64.4 0.00059 19.5 4.8 8.8 8 1 0 8 8 8 4 zinc-ribbon domain zf-ribbon_3 PF13248.6 KEG10669.1 - 7.6e-05 22.0 61.8 0.0097 15.3 5.5 9.8 11 0 0 11 11 11 4 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KEG10669.1 - 0.00027 21.6 40.5 0.25 12.1 0.9 7.6 8 1 0 8 8 8 4 zinc-ribbon family Rad50_zn_hook PF04423.14 KEG10669.1 - 0.00037 20.3 7.4 13 5.7 0.0 5.5 5 0 0 5 5 5 1 Rad50 zinc hook motif zf-CpG_bind_C PF12269.8 KEG10669.1 - 0.0062 16.4 10.2 8.3 6.1 0.0 5.4 6 0 0 6 6 6 1 CpG binding protein zinc finger C terminal domain NOB1_Zn_bind PF08772.11 KEG10669.1 - 0.008 16.3 1.1 0.008 16.3 1.1 7.4 7 1 1 8 8 8 3 Nin one binding (NOB1) Zn-ribbon like Sgf11 PF08209.11 KEG10669.1 - 0.085 12.4 0.2 0.085 12.4 0.2 7.1 9 0 0 9 9 9 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 KEG10669.1 - 0.26 10.9 33.9 4.9 6.8 0.1 9.8 10 1 1 11 11 11 0 Ubiquitin-Binding Zinc Finger c-SKI_SMAD_bind PF08782.10 KEG10669.1 - 0.42 10.9 0.0 0.42 10.9 0.0 4.5 6 0 0 6 6 6 0 c-SKI Smad4 binding domain zf-C2H2 PF00096.26 KEG10669.1 - 0.86 10.2 0.0 0.86 10.2 0.0 8.5 11 0 0 11 11 8 0 Zinc finger, C2H2 type Evr1_Alr PF04777.13 KEG10669.1 - 2.9 8.4 8.3 21 5.7 0.0 4.5 5 0 0 5 5 5 0 Erv1 / Alr family DGF-1_5 PF11038.8 KEG10670.1 - 1.2e-118 395.5 5.0 1.2e-118 395.5 5.0 2.3 2 0 0 2 2 2 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Beta_helix PF13229.6 KEG10670.1 - 4.9e-07 29.7 14.3 0.0041 17.0 0.0 8.5 8 1 0 9 9 9 3 Right handed beta helix region SHR3_chaperone PF08229.11 KEG10670.1 - 0.0015 17.5 0.0 0.0038 16.2 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein SH3 Pkinase PF00069.25 KEG10672.1 - 1.6e-33 116.2 0.0 2.8e-33 115.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10672.1 - 1.3e-27 96.7 0.0 2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG10672.1 - 1.7e-06 27.1 0.0 2.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG10672.1 - 0.039 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like ORC6 PF05460.13 KEG10673.1 - 0.026 13.8 4.3 0.03 13.6 4.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM176 PF14851.6 KEG10673.1 - 0.077 12.7 6.0 0.079 12.6 6.0 1.2 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.10 KEG10673.1 - 0.61 10.4 10.8 0.74 10.1 10.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 KEG10673.1 - 0.66 9.3 11.3 0.72 9.2 11.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger PGA2 PF07543.12 KEG10673.1 - 1.3 9.0 11.7 1.9 8.5 11.7 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 GCD14_N PF14801.6 KEG10675.1 - 0.16 11.8 4.3 0.34 10.8 4.3 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DUF3357 PF11837.8 KEG10675.1 - 0.19 12.2 3.3 0.24 11.9 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) STOP PF05217.12 KEG10676.1 - 0.0038 17.5 1.6 0.0077 16.5 1.6 1.5 1 0 0 1 1 1 1 STOP protein RXLR PF16810.5 KEG10676.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Peroxin-13_N PF04088.13 KEG10676.1 - 0.21 11.9 0.0 23 5.3 0.0 2.1 1 1 1 2 2 2 0 Peroxin 13, N-terminal region Glycophorin_A PF01102.18 KEG10676.1 - 0.25 11.6 3.1 0.49 10.6 0.5 2.0 1 1 1 2 2 2 0 Glycophorin A Mucin PF01456.17 KEG10676.1 - 0.88 9.6 23.8 23 5.0 23.8 2.6 1 1 0 1 1 1 0 Mucin-like glycoprotein SNF2_N PF00176.23 KEG10677.1 - 6.1e-42 143.6 0.1 1.1e-41 142.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG10677.1 - 5.6e-17 62.1 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG10677.1 - 5e-08 33.1 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG10677.1 - 2.7e-06 27.3 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KEG10677.1 - 0.0054 15.7 0.0 0.012 14.6 0.0 1.5 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SWI2_SNF2 PF18766.1 KEG10677.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Beta_helix PF13229.6 KEG10678.1 - 5.9e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 KEG10678.1 - 0.018 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Enkurin PF13864.6 KEG10679.1 - 3.4e-23 81.9 4.9 3.4e-23 81.9 4.9 2.3 2 0 0 2 2 2 1 Calmodulin-binding Thioredoxin PF00085.20 KEG10680.1 - 1.8e-20 72.8 0.1 2e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEG10680.1 - 0.00023 21.6 0.1 0.00089 19.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KEG10680.1 - 0.025 14.5 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 KEG10680.1 - 0.059 12.7 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 KEG10680.1 - 0.059 12.3 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosducin Glutaredoxin PF00462.24 KEG10680.1 - 0.073 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Acetyltransf_1 PF00583.25 KEG10681.1 - 2.6e-17 63.1 0.0 1.7e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG10681.1 - 4.9e-12 45.9 0.0 5.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEG10681.1 - 3.1e-09 37.1 0.0 0.0027 18.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEG10681.1 - 0.002 18.2 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KEG10681.1 - 0.0068 16.5 0.0 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG10681.1 - 0.0091 15.9 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein PseudoU_synth_2 PF00849.22 KEG10682.1 - 4.7e-23 82.0 0.0 1.1e-22 80.8 0.0 1.6 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF412 PF04217.13 KEG10682.1 - 0.073 13.0 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF412 Cmc1 PF08583.10 KEG10683.1 - 5.5e-06 26.3 1.9 1.1e-05 25.3 1.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KEG10683.1 - 0.0005 20.0 2.0 0.00088 19.2 2.0 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 KEG10683.1 - 0.017 15.3 5.4 0.12 12.6 1.7 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 KEG10683.1 - 0.23 11.6 1.3 25 5.1 0.2 2.4 2 0 0 2 2 2 0 CHCH domain PX PF00787.24 KEG10684.1 - 3e-14 53.0 0.0 8.5e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 PX domain DHHA2 PF02833.14 KEG10685.1 - 5.8e-19 68.7 0.0 8.6e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KEG10685.1 - 6.5e-07 29.5 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 DHH family WD40 PF00400.32 KEG10686.1 - 1.3e-20 73.3 12.0 0.045 14.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat WWE PF02825.20 KEG10686.1 - 4.9e-13 49.5 0.0 1.2e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 WWE domain Nup160 PF11715.8 KEG10686.1 - 0.041 12.5 0.1 0.065 11.9 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3047 PF11249.8 KEG10686.1 - 0.063 12.7 0.1 0.17 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) Chloroplast_duf PF14476.6 KEG10687.1 - 0.19 10.7 0.7 0.36 9.8 0.7 1.4 1 0 0 1 1 1 0 Petal formation-expressed LPD23 PF18838.1 KEG10687.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.1 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 Prefoldin PF02996.17 KEG10689.1 - 2.2e-21 76.0 0.5 2.7e-21 75.7 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KEG10689.1 - 0.0088 16.0 0.4 0.09 12.7 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit End3 PF12761.7 KEG10689.1 - 0.0098 16.1 0.5 0.019 15.2 0.4 1.6 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 KxDL PF10241.9 KEG10689.1 - 0.087 13.1 0.4 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein Sec2p PF06428.11 KEG10689.1 - 0.28 11.2 3.8 0.9 9.6 1.4 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p MMR_HSR1 PF01926.23 KEG10690.1 - 6e-15 55.3 0.0 5.5e-13 49.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG10690.1 - 2.6e-07 30.3 0.1 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEG10690.1 - 1.2e-05 25.3 0.1 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KEG10690.1 - 0.0023 17.5 0.1 3 7.4 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEG10690.1 - 0.0029 17.7 1.1 0.042 13.9 0.2 2.8 1 1 1 2 2 2 1 Dynamin family FUSC_2 PF13515.6 KEG10691.1 - 1.9e-10 40.9 12.2 1.9e-10 40.9 12.2 3.4 3 1 1 4 4 4 1 Fusaric acid resistance protein-like Plasmodium_Vir PF05795.11 KEG10691.1 - 0.16 11.4 3.0 0.32 10.4 3.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 KEG10691.1 - 0.57 7.2 5.1 0.8 6.7 5.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 KEG10691.1 - 4.8 6.2 10.0 8.5 5.4 10.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Thioredoxin PF00085.20 KEG10692.1 - 0.00013 21.9 0.4 0.0072 16.3 0.1 2.9 2 1 0 2 2 2 1 Thioredoxin DUF5082 PF16888.5 KEG10692.1 - 0.017 15.4 0.2 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 KEG10692.1 - 0.071 11.7 3.2 0.032 12.9 0.6 1.7 2 0 0 2 2 2 0 AAA domain DUF4278 PF14105.6 KEG10692.1 - 0.074 13.5 0.2 0.19 12.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) Metallophos PF00149.28 KEG10693.1 - 9.4e-33 114.4 0.0 4.7e-32 112.1 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase NARG2_C PF10505.9 KEG10694.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus GF_recep_IV PF14843.6 KEG10694.1 - 0.014 15.2 1.1 0.014 15.2 1.1 2.5 3 0 0 3 3 3 0 Growth factor receptor domain IV ScdA_N PF04405.14 KEG10694.1 - 0.078 12.6 1.9 5.2 6.8 0.1 2.7 2 1 1 3 3 3 0 Domain of Unknown function (DUF542) adh_short PF00106.25 KEG10695.1 - 1e-20 74.0 0.0 1.9e-19 69.9 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG10695.1 - 3.4e-12 46.4 0.0 9.5e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG10695.1 - 4.5e-07 30.0 0.4 7.7e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 KR domain Lipase_3 PF01764.25 KEG10696.1 - 1.1e-08 35.1 0.1 6.5e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.20 KEG10696.1 - 7.2e-05 23.0 0.0 7.2e-05 23.0 0.0 2.5 3 0 0 3 3 3 1 Thioesterase domain PGAP1 PF07819.13 KEG10696.1 - 0.00022 21.0 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein YjeF_N PF03853.15 KEG10696.1 - 0.033 14.1 0.1 0.09 12.7 0.1 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus HEPN_STY4199 PF18729.1 KEG10696.1 - 0.066 12.4 3.2 0.1 11.8 2.6 1.6 2 0 0 2 2 2 0 STY4199-like HEPN adh_short PF00106.25 KEG10697.1 - 6.7e-23 81.2 0.4 6.2e-14 51.9 0.0 3.0 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEG10697.1 - 5.6e-14 52.3 0.2 3.9e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG10697.1 - 0.012 15.5 0.2 0.53 10.2 0.3 2.3 2 0 0 2 2 2 0 KR domain Cys_rich_CWC PF14375.6 KEG10697.1 - 2 8.9 6.0 8.5 6.9 0.2 2.8 2 1 1 3 3 3 0 Cysteine-rich CWC Pkinase PF00069.25 KEG10698.1 - 2.2e-61 207.5 0.0 2.8e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10698.1 - 4.4e-31 108.1 0.0 1.1e-30 106.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10698.1 - 5.2e-09 35.8 0.0 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEG10698.1 - 1.1e-06 28.8 0.9 0.0041 17.1 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KEG10698.1 - 2.4e-05 24.1 0.0 0.0059 16.3 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KEG10698.1 - 0.00027 19.8 0.0 0.00062 18.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG10698.1 - 0.0015 17.9 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEG10698.1 - 0.0058 16.3 0.0 0.016 14.8 0.0 1.6 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KEG10698.1 - 0.016 14.2 0.1 0.093 11.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Cytochrom_C_2 PF01322.20 KEG10699.1 - 0.0016 19.3 2.0 0.0016 19.3 2.0 2.5 3 0 0 3 3 3 1 Cytochrome C' Fez1 PF06818.15 KEG10699.1 - 0.0019 18.7 6.3 0.0019 18.7 6.3 2.2 1 1 1 2 2 2 1 Fez1 Haem_bd PF14376.6 KEG10699.1 - 0.036 14.0 0.2 0.093 12.7 0.2 1.8 1 0 0 1 1 1 0 Haem-binding domain p25-alpha PF05517.12 KEG10699.1 - 0.13 12.4 1.1 0.23 11.6 0.3 1.8 2 1 0 2 2 2 0 p25-alpha Cytochrome_C7 PF14522.6 KEG10699.1 - 0.47 10.5 4.1 0.23 11.5 0.6 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Phage_GPO PF05929.11 KEG10699.1 - 0.63 9.6 12.5 0.069 12.8 6.6 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF848 PF05852.11 KEG10699.1 - 0.86 9.7 14.3 6.6 6.8 7.4 3.6 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 KEG10699.1 - 1.7 8.0 19.5 4.7 6.5 15.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 KEG10699.1 - 2.7 8.2 27.1 4.9 7.4 0.3 3.4 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KEG10699.1 - 3.6 6.4 21.5 2.2 7.1 15.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein MPS2 PF17060.5 KEG10699.1 - 5 6.3 7.5 17 4.5 7.7 1.9 2 1 0 2 2 2 0 Monopolar spindle protein 2 KASH_CCD PF14662.6 KEG10699.1 - 6.7 6.5 26.8 3.9 7.3 14.3 3.3 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH PC-Esterase PF13839.6 KEG10700.1 - 7.3e-14 52.2 2.7 1.1e-11 45.0 2.7 2.9 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF844 PF05815.11 KEG10700.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Synaptobrevin PF00957.21 KEG10701.1 - 7.4e-15 54.5 0.3 1.3e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEG10701.1 - 3.8e-07 30.1 0.0 6.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Vps5 PF09325.10 KEG10702.1 - 9.2e-22 77.7 9.0 1.3e-21 77.3 9.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KEG10702.1 - 9.9e-19 67.4 0.0 2.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 KEG10702.1 - 7.5e-08 32.1 5.1 4.9e-05 22.9 5.1 2.3 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Fez1 PF06818.15 KEG10702.1 - 0.21 12.0 12.5 0.45 10.9 12.5 1.6 1 0 0 1 1 1 0 Fez1 Laminin_II PF06009.12 KEG10702.1 - 0.4 10.7 5.1 3.2 7.8 0.5 2.5 1 1 1 2 2 2 0 Laminin Domain II T3SS_needle_E PF08988.10 KEG10702.1 - 2.5 8.3 7.3 12 6.1 1.3 3.3 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Syntaxin_2 PF14523.6 KEG10702.1 - 5.9 7.3 6.6 5.8 7.4 2.3 2.9 1 1 2 3 3 3 0 Syntaxin-like protein FlaC_arch PF05377.11 KEG10702.1 - 8.3 6.9 6.3 6.8 7.2 0.3 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Peptidase_M8 PF01457.16 KEG10703.1 - 5.8e-102 342.1 0.0 8.4e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin FAM163 PF15069.6 KEG10704.1 - 0.081 13.4 0.0 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 FAM163 family FAA_hydrolase PF01557.18 KEG10705.1 - 3.3e-41 141.3 0.0 3.9e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HECT PF00632.25 KEG10706.1 - 4.3e-66 223.5 0.0 8.2e-66 222.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 KEG10706.1 - 0.0059 16.9 6.3 0.019 15.3 6.3 1.9 1 0 0 1 1 1 1 C1 domain zf-B_box PF00643.24 KEG10706.1 - 0.24 11.6 11.2 0.76 10.0 11.2 1.9 1 0 0 1 1 1 0 B-box zinc finger RRP7 PF12923.7 KEG10707.1 - 1.2e-05 25.4 5.6 1.2e-05 25.4 5.6 2.7 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF3492 PF11997.8 KEG10707.1 - 0.059 13.1 0.2 0.059 13.1 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3492) RRM_1 PF00076.22 KEG10708.1 - 4.1e-18 65.0 0.0 5.2e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG10708.1 - 2.4e-05 23.9 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG10708.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif HA2 PF04408.23 KEG10709.1 - 3.2e-18 66.0 0.1 1.3e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEG10709.1 - 4.1e-16 59.1 0.0 8.8e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEG10709.1 - 1.8e-12 47.6 0.1 5.3e-12 46.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG10709.1 - 6.2e-09 35.9 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KEG10709.1 - 0.00016 22.0 0.1 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEG10709.1 - 0.0012 19.1 1.0 0.013 15.8 0.3 2.7 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEG10709.1 - 0.0013 17.8 0.0 0.0037 16.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein RWD PF05773.22 KEG10709.1 - 0.0097 16.2 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 1 RWD domain AAA_30 PF13604.6 KEG10709.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEG10709.1 - 0.034 14.0 0.1 17 5.3 0.1 3.1 2 0 0 2 2 2 0 NACHT domain UEV PF05743.13 KEG10709.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 UEV domain ATPase PF06745.13 KEG10709.1 - 0.099 12.0 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KEG10709.1 - 0.32 11.5 1.0 0.76 10.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 KEG10709.1 - 0.33 11.1 7.3 0.085 13.0 2.9 2.2 2 0 0 2 2 2 0 Zinc knuckle RRM_1 PF00076.22 KEG10710.1 - 2.7e-18 65.6 0.0 3.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG10710.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KEG10710.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif HhH-GPD PF00730.25 KEG10711.1 - 6.5e-18 65.2 0.0 1.4e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEG10711.1 - 4.7e-07 29.4 0.0 9.6e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF763 PF05559.11 KEG10711.1 - 0.016 14.4 0.0 0.1 11.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF763) HHH_5 PF14520.6 KEG10711.1 - 0.034 14.8 0.0 0.48 11.1 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain PIG-L PF02585.17 KEG10712.1 - 1.2e-24 87.4 0.0 1.8e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF3253 PF11625.8 KEG10713.1 - 0.0083 16.3 1.4 0.041 14.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3253) Seadorna_VP6 PF07407.11 KEG10713.1 - 0.44 9.4 6.4 0.19 10.7 4.2 1.4 1 1 1 2 2 2 0 Seadornavirus VP6 protein WXG100 PF06013.12 KEG10713.1 - 7.3 6.9 11.1 0.93 9.8 2.7 3.0 2 1 1 3 3 3 0 Proteins of 100 residues with WXG PEX11 PF05648.14 KEG10714.1 - 2.6e-14 53.2 1.6 1.9e-12 47.1 1.6 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SOAR PF16533.5 KEG10714.1 - 0.12 12.4 0.1 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region Suf PF05843.14 KEG10715.1 - 0.0019 18.3 0.0 0.0048 16.9 0.0 1.7 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) MIIP PF15734.5 KEG10715.1 - 0.07 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Migration and invasion-inhibitory NIP_1 PF08995.10 KEG10715.1 - 0.17 12.3 0.2 0.48 10.9 0.2 1.7 1 0 0 1 1 1 0 Necrosis inducing protein-1 ANAPC4_WD40 PF12894.7 KEG10717.1 - 0.0025 18.1 0.0 0.88 9.9 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UPF0242 PF06785.11 KEG10718.1 - 0.65 10.1 15.7 0.11 12.6 2.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spb1_C PF07780.12 KEG10718.1 - 0.87 9.2 9.1 0.38 10.3 4.5 2.2 1 1 1 2 2 2 0 Spb1 C-terminal domain SurA_N_3 PF13624.6 KEG10720.1 - 1.8 8.4 5.8 0.34 10.7 0.9 2.0 2 0 0 2 2 2 0 SurA N-terminal domain CAP59_mtransfer PF11735.8 KEG10722.1 - 3e-47 161.3 0.0 1.8e-46 158.8 0.0 2.2 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.22 KEG10724.1 - 3.2e-26 92.3 0.6 2.2e-24 86.3 0.1 3.0 2 1 0 2 2 2 1 Subtilase family DUF4381 PF14316.6 KEG10724.1 - 0.11 12.7 1.5 10 6.3 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Dpy-30 PF05186.13 KEG10726.1 - 1.9e-07 30.6 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Phage_capsid PF05065.13 KEG10726.1 - 0.084 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family Pox_MCEL PF03291.16 KEG10728.1 - 6.8e-45 153.6 0.0 9.9e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_C PF03919.15 KEG10728.1 - 7.2e-09 36.3 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 KEG10728.1 - 5.2e-08 33.0 0.1 0.021 14.6 0.0 3.3 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_25 PF13649.6 KEG10728.1 - 0.0016 19.1 0.1 0.1 13.3 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain AAA_18 PF13238.6 KEG10728.1 - 0.078 13.5 0.0 1.6 9.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain Methyltransf_12 PF08242.12 KEG10728.1 - 0.091 13.5 0.0 0.36 11.6 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain DnaJ_C PF01556.18 KEG10729.1 - 6.1e-35 120.5 0.0 8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KEG10729.1 - 8.4e-15 54.9 13.0 1.8e-14 53.8 13.0 1.6 1 0 0 1 1 1 1 DnaJ central domain zf-C3HC4_3 PF13920.6 KEG10729.1 - 0.00048 19.9 5.9 0.025 14.4 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 KEG10729.1 - 0.0077 16.2 7.5 0.17 11.9 0.5 2.4 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KEG10729.1 - 0.021 14.8 14.3 0.29 11.1 2.3 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_2 PF13639.6 KEG10729.1 - 2.1 8.7 9.3 1.1 9.6 1.0 2.7 2 1 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KEG10729.1 - 3 7.9 7.6 4.3 7.4 1.4 2.6 2 0 0 2 2 2 0 zinc-RING finger domain ADK_lid PF05191.14 KEG10729.1 - 4 7.5 6.7 1.8 8.6 0.6 3.8 5 1 0 5 5 5 0 Adenylate kinase, active site lid DZR PF12773.7 KEG10729.1 - 4.8 7.3 9.3 41 4.3 5.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.6 KEG10729.1 - 9.1 6.8 10.2 19 5.7 1.5 3.6 1 1 2 3 3 3 0 Restriction alleviation protein Lar Rad10 PF03834.14 KEG10730.1 - 4.7e-14 52.4 0.0 6.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KEG10730.1 - 4.8e-05 23.9 0.0 8.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KEG10730.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 KEG10730.1 - 0.02 14.7 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif R3H PF01424.22 KEG10731.1 - 3.5e-09 36.5 0.1 8.5e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 R3H domain HTH_19 PF12844.7 KEG10732.1 - 0.78 9.8 6.5 0.37 10.8 0.8 3.0 3 1 0 3 3 3 0 Helix-turn-helix domain ADK PF00406.22 KEG10732.1 - 2.2 8.4 6.1 1.8 8.7 1.2 2.5 2 0 0 2 2 2 0 Adenylate kinase Sulfotransfer_4 PF17784.1 KEG10732.1 - 2.7 7.8 15.9 19 5.0 13.2 2.9 1 1 1 2 2 2 0 Sulfotransferase domain SET PF00856.28 KEG10733.1 - 6.7e-06 26.6 0.2 1.6e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 SET domain Ribosomal_60s PF00428.19 KEG10737.1 - 1.9e-25 89.2 20.4 6.2e-23 81.2 16.2 2.1 2 0 0 2 2 2 2 60s Acidic ribosomal protein Homeobox_KN PF05920.11 KEG10737.1 - 0.0017 18.2 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Homeobox KN domain DUF3933 PF13069.6 KEG10737.1 - 0.023 14.6 4.4 2.3 8.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) HTH_31 PF13560.6 KEG10737.1 - 0.046 14.1 0.0 19 5.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain RhoGAP PF00620.27 KEG10738.1 - 7.9e-11 42.0 0.0 1.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 KEG10738.1 - 1.9e-07 30.8 0.0 3.3e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nucleoside_tran PF01733.18 KEG10739.1 - 4.7e-33 114.9 1.1 1.2e-32 113.6 1.1 1.6 1 1 0 1 1 1 1 Nucleoside transporter UFC1 PF08694.11 KEG10740.1 - 4.9e-64 214.6 0.3 5.4e-64 214.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 KEG10740.1 - 0.003 17.2 0.2 0.0037 16.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEG10740.1 - 0.037 14.3 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain CorA PF01544.18 KEG10741.1 - 1.8e-40 139.1 0.1 2.3e-40 138.8 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein IQ PF00612.27 KEG10745.1 - 6.7e-09 34.8 19.6 0.0021 17.7 0.2 5.5 5 0 0 5 5 5 4 IQ calmodulin-binding motif Helicase_C PF00271.31 KEG10746.1 - 2.3e-15 56.9 1.5 2.2e-14 53.7 0.4 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KEG10747.1 - 9.5e-13 48.9 0.0 1.7e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 KEG10747.1 - 0.00013 22.3 0.0 0.00034 20.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pox_C4_C10 PF03336.13 KEG10747.1 - 0.032 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.20 KEG10747.1 - 0.038 14.5 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 KEG10748.1 - 0.00018 22.2 0.1 0.02 15.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KEG10748.1 - 0.00072 19.0 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KEG10748.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 KEG10748.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KEG10748.1 - 0.042 14.5 0.0 0.83 10.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain FAA_hydrolase PF01557.18 KEG10748.1 - 0.063 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Met_10 PF02475.16 KEG10748.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 KEG10748.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 KEG10748.1 - 0.12 13.4 0.1 0.32 12.1 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain ADK PF00406.22 KEG10749.1 - 4e-26 91.9 0.0 7.2e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEG10749.1 - 1.2e-17 64.6 0.0 3.5e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEG10749.1 - 2.4e-08 34.3 0.0 4.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG10749.1 - 1e-07 32.6 0.0 1.7e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEG10749.1 - 0.0015 18.8 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF5586 PF17824.1 KEG10749.1 - 0.0038 16.4 0.0 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5586) Cytidylate_kin PF02224.18 KEG10749.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase RIIa PF02197.17 KEG10749.1 - 0.007 16.0 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SKI PF01202.22 KEG10749.1 - 0.01 16.0 0.1 0.061 13.4 0.0 2.3 3 0 0 3 3 3 0 Shikimate kinase Thymidylate_kin PF02223.17 KEG10749.1 - 0.051 13.2 0.0 2.6 7.7 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase DUF5582 PF17819.1 KEG10749.1 - 0.063 13.7 0.4 0.16 12.4 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5582) Hydin_ADK PF17213.3 KEG10749.1 - 0.19 12.0 0.0 1.3 9.2 0.0 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Ribosomal_L27A PF00828.19 KEG10750.1 - 6.9e-06 26.8 0.0 1.3e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A EFhand_Ca_insen PF08726.10 KEG10750.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Myosin_head PF00063.21 KEG10751.1 - 5.8e-166 553.6 0.0 8.9e-166 553.0 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 KEG10751.1 - 0.028 14.7 0.1 0.22 11.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain HAS-barrel PF09378.10 KEG10751.1 - 0.057 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 HAS barrel domain Tyosinase_C PF18132.1 KEG10751.1 - 0.083 13.6 0.3 8.4 7.1 0.1 2.8 2 0 0 2 2 2 0 Tyosinase C-terminal domain AAA_16 PF13191.6 KEG10751.1 - 0.63 10.4 0.0 0.63 10.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain ASF1_hist_chap PF04729.13 KEG10752.1 - 1.2e-15 57.7 0.0 1.5e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Sedlin_N PF04628.13 KEG10753.1 - 1.9e-24 86.2 0.0 2.1e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KEG10753.1 - 0.02 14.8 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family Glucosamine_iso PF01182.20 KEG10754.1 - 5.7e-56 189.9 0.1 6.7e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Penicil_amidase PF01804.18 KEG10755.1 - 1.4e-126 424.1 0.1 1.6e-126 424.0 0.1 1.0 1 0 0 1 1 1 1 Penicillin amidase LRR_6 PF13516.6 KEG10757.1 - 8.1e-08 31.7 17.3 0.0019 18.1 0.4 7.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KEG10757.1 - 2.8 8.5 4.9 2.1 8.9 0.3 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) OsmC PF02566.19 KEG10758.1 - 1.4e-08 35.1 0.3 2.3e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 OsmC-like protein NACHT_N PF17100.5 KEG10758.1 - 0.00033 20.6 2.6 0.00033 20.6 2.6 1.6 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Spore_III_AF PF09581.10 KEG10758.1 - 0.71 9.9 4.3 1.1 9.3 4.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Focal_AT PF03623.13 KEG10759.1 - 0.019 15.0 11.1 0.25 11.4 2.3 2.8 2 1 0 2 2 2 0 Focal adhesion targeting region FliD_C PF07195.12 KEG10759.1 - 0.39 10.1 2.4 9.8 5.5 0.0 2.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus zinc_ribbon_16 PF17034.5 KEG10760.1 - 0.019 15.2 24.6 0.057 13.6 21.2 3.1 2 1 0 2 2 2 0 Zinc-ribbon like family zinc_ribbon_16 PF17034.5 KEG10761.1 - 1.8e-10 41.1 6.0 4e-10 40.0 6.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KEG10761.1 - 0.0078 15.8 13.8 0.032 13.9 13.8 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Dopey_N PF04118.14 KEG10761.1 - 0.044 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Dopey, N-terminal PPR PF01535.20 KEG10762.1 - 0.0037 17.4 0.4 0.59 10.5 0.0 3.9 4 0 0 4 4 4 1 PPR repeat ANAPC4_WD40 PF12894.7 KEG10764.1 - 0.002 18.4 0.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3648 PF12364.8 KEG10766.1 - 3.6e-13 50.0 0.2 3.6e-13 50.0 0.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3648) EF-hand_7 PF13499.6 KEG10767.1 - 6.6e-14 52.1 2.5 3.8e-08 33.7 1.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG10767.1 - 1.2e-12 46.6 0.6 0.0017 18.2 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KEG10767.1 - 2.1e-12 45.6 1.8 0.0014 18.0 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KEG10767.1 - 8e-10 38.4 1.3 0.0016 18.3 0.1 4.3 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KEG10767.1 - 3.7e-05 23.0 1.1 0.25 10.9 0.1 3.1 3 0 0 3 3 3 2 EF hand DUF1461 PF07314.11 KEG10767.1 - 0.048 13.6 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Ras PF00071.22 KEG10768.1 - 1.2e-52 177.8 0.0 8.2e-52 175.1 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEG10768.1 - 1.7e-30 105.7 0.2 4.8e-28 97.8 0.2 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG10768.1 - 1.3e-13 50.7 0.0 4.4e-12 45.8 0.0 2.0 1 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEG10768.1 - 2.3e-05 24.0 0.0 3.4e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEG10768.1 - 0.0011 19.0 0.3 0.085 12.8 0.5 2.3 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KEG10768.1 - 0.0023 18.0 0.0 0.005 16.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEG10768.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.9 KEG10768.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3873 PF12989.7 KEG10768.1 - 0.042 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_29 PF13555.6 KEG10768.1 - 0.055 13.2 0.0 0.6 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KEG10768.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DnaJ PF00226.31 KEG10769.1 - 6.9e-18 64.5 1.0 2e-17 63.0 1.0 1.9 1 0 0 1 1 1 1 DnaJ domain PUF PF00806.19 KEG10770.1 - 4.7e-50 164.6 9.5 1.8e-06 27.3 0.0 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KEG10770.1 - 0.019 15.3 1.1 0.75 10.1 0.1 3.6 2 2 1 3 3 3 0 CPL (NUC119) domain DUF4736 PF15883.5 KEG10770.1 - 0.02 14.7 0.3 0.02 14.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) MAGE PF01454.19 KEG10770.1 - 0.37 10.4 2.3 1.1 8.9 2.0 1.9 2 0 0 2 2 2 0 MAGE family HisG PF01634.18 KEG10772.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 ATP phosphoribosyltransferase DUF3975 PF13126.6 KEG10772.1 - 3 8.3 6.3 0.76 10.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Malate_DH PF12434.8 KEG10773.1 - 0.22 11.6 0.2 0.22 11.6 0.2 3.6 4 0 0 4 4 4 0 Malate dehydrogenase enzyme CDT1_C PF16679.5 KEG10773.1 - 0.94 9.9 4.7 1 9.9 2.2 2.3 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain SUIM_assoc PF16619.5 KEG10773.1 - 2.7 8.1 8.2 0.3 11.2 0.3 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CDC45 PF02724.14 KEG10774.1 - 0.16 10.2 0.5 0.2 9.9 0.5 1.0 1 0 0 1 1 1 0 CDC45-like protein LsmAD PF06741.13 KEG10775.1 - 3.3e-19 69.2 2.8 3.3e-19 69.2 2.8 2.3 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 KEG10775.1 - 1.3e-15 57.3 0.0 2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Paf67 PF10255.9 KEG10777.1 - 0.0095 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KEG10777.1 - 0.051 13.7 0.2 0.24 11.6 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG10777.1 - 0.083 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KEG10778.1 - 1.5e-15 56.8 10.1 2.7e-15 56.0 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG10778.1 - 1e-08 34.9 9.9 2.8e-08 33.5 9.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEG10778.1 - 8.2e-06 26.1 11.4 8.2e-06 26.1 11.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KEG10778.1 - 0.00012 21.9 12.9 0.00021 21.1 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG10778.1 - 0.0037 17.2 11.3 0.0084 16.1 11.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEG10778.1 - 0.0071 16.2 12.5 0.0071 16.2 12.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KEG10778.1 - 0.0087 15.7 8.1 0.018 14.7 8.1 1.5 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_4 PF14570.6 KEG10778.1 - 0.13 12.0 7.9 0.29 11.0 7.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPH PF13868.6 KEG10779.1 - 2.8e-63 213.6 155.1 2.8e-63 213.6 155.1 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain TFIIA PF03153.13 KEG10780.1 - 0.0041 17.2 15.8 0.0048 16.9 15.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 KEG10780.1 - 0.018 14.9 12.0 0.022 14.6 12.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Band_3_cyto PF07565.13 KEG10780.1 - 0.12 12.1 10.8 0.17 11.7 10.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PNISR PF15996.5 KEG10780.1 - 0.12 12.6 16.7 0.17 12.2 16.7 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR ALMT PF11744.8 KEG10780.1 - 0.24 10.2 6.5 0.32 9.8 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter eIF-3_zeta PF05091.12 KEG10780.1 - 0.51 9.2 12.1 0.58 9.1 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 KEG10780.1 - 0.74 9.7 8.8 0.99 9.3 8.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 KEG10780.1 - 0.78 9.9 6.4 0.99 9.5 6.4 1.1 1 0 0 1 1 1 0 DDHD domain OATP PF03137.20 KEG10780.1 - 0.96 7.6 3.7 1.4 7.1 3.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MAJIN PF15077.6 KEG10780.1 - 1.1 9.0 9.1 1.4 8.7 9.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein RR_TM4-6 PF06459.12 KEG10780.1 - 1.4 8.6 9.0 2 8.2 9.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.9 KEG10780.1 - 1.5 8.4 18.7 2.3 7.8 18.7 1.3 1 0 0 1 1 1 0 DDRGK domain CCDC53 PF10152.9 KEG10780.1 - 1.5 9.3 13.3 3 8.2 13.3 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex NPR3 PF03666.13 KEG10780.1 - 1.7 7.4 10.3 2 7.1 10.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 KEG10780.1 - 2.1 7.7 7.6 2.6 7.4 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4778 PF16008.5 KEG10780.1 - 2.1 8.3 13.6 2.8 7.9 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Presenilin PF01080.17 KEG10780.1 - 2.2 6.9 12.1 2.7 6.7 12.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KEG10780.1 - 3 5.8 10.8 3.6 5.6 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Connexin PF00029.19 KEG10780.1 - 3.6 7.3 5.4 4.6 6.9 5.4 1.3 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 KEG10780.1 - 4.1 7.4 8.5 5.4 7.0 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Afi1 PF07792.12 KEG10780.1 - 4.6 7.7 8.2 8.1 6.9 8.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Plasmodium_Vir PF05795.11 KEG10780.1 - 6.4 6.1 6.0 8 5.8 6.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-C3HC4_3 PF13920.6 KEG10781.1 - 1.9e-10 40.5 11.1 1.9e-10 40.5 11.1 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG10781.1 - 0.0012 18.7 11.9 0.0012 18.7 11.9 3.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEG10781.1 - 0.033 14.1 13.0 0.033 14.1 13.0 3.5 2 1 0 2 2 2 0 zinc-RING finger domain Ras PF00071.22 KEG10782.1 - 9.3e-21 74.1 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Ras family ABC_sub_bind PF04392.12 KEG10782.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein zf-RING_2 PF13639.6 KEG10785.1 - 8.8e-11 42.0 6.4 2.4e-10 40.6 4.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KEG10785.1 - 7.7e-09 35.7 6.4 4.2e-08 33.3 6.4 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEG10785.1 - 4.3e-07 29.8 1.4 4.3e-07 29.8 1.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG10785.1 - 1.8e-06 27.8 1.9 9.4e-05 22.4 0.7 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG10785.1 - 2.9e-06 27.0 2.4 8.2e-06 25.6 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG10785.1 - 6.7e-06 25.9 3.7 6.7e-06 25.9 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEG10785.1 - 7.5e-06 25.6 1.6 1.3e-05 24.8 0.4 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KEG10785.1 - 0.0018 18.1 5.6 0.0018 18.1 5.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG10785.1 - 0.0022 17.8 3.6 0.0056 16.5 3.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KEG10785.1 - 0.003 17.1 3.2 0.01 15.4 3.2 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KEG10785.1 - 0.019 15.0 4.6 0.074 13.1 4.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ADK_lid PF05191.14 KEG10785.1 - 0.037 14.0 1.4 0.46 10.5 0.1 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid FANCL_C PF11793.8 KEG10785.1 - 0.041 14.1 2.0 0.11 12.7 2.0 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KEG10785.1 - 0.12 12.2 7.6 0.92 9.4 5.1 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KEG10785.1 - 0.21 11.6 2.9 0.72 9.9 2.9 1.9 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 KEG10785.1 - 0.37 10.7 2.6 0.87 9.5 2.6 1.7 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.27 KEG10786.1 - 4.1e-09 36.2 1.8 0.00015 21.7 0.4 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein COX7C PF02935.16 KEG10786.1 - 0.052 13.8 0.8 0.12 12.6 0.8 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc zf-RanBP PF00641.18 KEG10788.1 - 2.2e-07 30.0 2.7 4.3e-07 29.1 2.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others VHS PF00790.19 KEG10788.1 - 6.6e-06 26.0 0.0 9.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 VHS domain Vps36-NZF-N PF16988.5 KEG10788.1 - 0.0067 15.8 0.4 0.012 15.0 0.4 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain RrnaAD PF00398.20 KEG10790.1 - 1.4e-61 207.9 0.0 1.7e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KEG10790.1 - 3.8e-08 33.9 0.0 7.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG10790.1 - 1.4e-05 25.7 0.0 3.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG10790.1 - 0.00027 20.8 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEG10790.1 - 0.0015 18.3 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KEG10790.1 - 0.0035 18.1 0.0 0.0068 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KEG10790.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.6 KEG10790.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pox_D5 PF03288.16 KEG10790.1 - 0.03 14.8 0.4 0.066 13.7 0.4 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like MTS PF05175.14 KEG10790.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KEG10790.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KEG10790.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KEG10790.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_28 PF02636.17 KEG10790.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.16 KEG10791.1 - 0.0022 17.0 3.3 0.0022 17.0 3.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4781 PF16013.5 KEG10791.1 - 0.87 8.3 2.9 1.1 8.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) PNK3P PF08645.11 KEG10793.1 - 1.8e-49 167.5 0.0 3.4e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KEG10793.1 - 1e-12 48.5 0.0 3.1e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KEG10793.1 - 0.0059 15.9 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KEG10793.1 - 0.0067 16.7 0.0 0.018 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEG10793.1 - 0.01 16.1 0.0 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEG10793.1 - 0.033 14.3 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KEG10793.1 - 0.051 14.1 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KEG10793.1 - 0.062 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase tRNA_lig_kinase PF08303.11 KEG10793.1 - 0.067 13.3 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_16 PF13191.6 KEG10793.1 - 0.074 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KEG10793.1 - 0.12 11.6 0.0 0.95 8.6 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KEG10793.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NAD_binding_2 PF03446.15 KEG10794.1 - 1.4e-51 174.8 2.4 2.8e-51 173.8 2.4 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEG10794.1 - 2.8e-38 130.9 0.5 5.9e-38 129.9 0.5 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KEG10794.1 - 2.4e-05 24.8 1.7 3.9e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEG10794.1 - 3.1e-05 23.4 1.5 5.5e-05 22.6 0.1 2.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEG10794.1 - 3.3e-05 24.0 0.1 6.9e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KEG10794.1 - 0.00071 19.5 0.3 0.00071 19.5 0.3 2.3 2 2 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEG10794.1 - 0.0035 17.0 0.2 0.99 8.9 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 KEG10794.1 - 0.012 15.2 1.0 0.015 14.9 0.2 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh PF00984.19 KEG10794.1 - 0.019 15.1 0.2 0.051 13.8 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain ApbA PF02558.16 KEG10794.1 - 0.025 14.2 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KEG10794.1 - 0.051 13.8 0.4 0.18 12.1 0.1 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain START PF01852.19 KEG10795.1 - 9.9e-05 21.8 0.1 0.00025 20.5 0.1 1.6 1 1 0 1 1 1 1 START domain Rubis-subs-bind PF09273.11 KEG10796.1 - 1.4e-07 32.2 0.2 6.4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 KEG10796.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 SET domain WW PF00397.26 KEG10798.1 - 5.2e-11 42.4 4.4 5.2e-11 42.4 4.4 1.8 2 0 0 2 2 2 1 WW domain zf-CCCH PF00642.24 KEG10798.1 - 9e-08 31.8 1.0 1.5e-07 31.2 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG10798.1 - 6.7e-06 26.0 2.4 1.2e-05 25.1 2.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEG10798.1 - 4.2e-05 23.2 1.1 8e-05 22.3 1.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KEG10798.1 - 0.041 14.1 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 KEG10798.1 - 0.047 14.4 0.2 0.075 13.7 0.2 1.4 1 0 0 1 1 1 0 Torus domain VWA_CoxE PF05762.14 KEG10800.1 - 0.028 13.8 0.2 0.042 13.2 0.2 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein RINGv PF12906.7 KEG10801.1 - 5.3e-11 42.5 11.4 1.2e-10 41.3 11.4 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KEG10801.1 - 0.95 9.7 5.5 3 8.1 5.5 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain Pkinase PF00069.25 KEG10802.1 - 1.9e-72 243.8 0.0 2.6e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10802.1 - 7.2e-35 120.5 0.0 7.4e-34 117.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG10802.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase p450 PF00067.22 KEG10803.1 - 2.5e-62 211.1 0.1 3.5e-62 210.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4734 PF15881.5 KEG10804.1 - 0.083 13.1 0.0 0.32 11.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) DEAD PF00270.29 KEG10807.1 - 1.2e-35 122.9 0.0 1.8e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG10807.1 - 3.7e-06 27.0 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEG10807.1 - 0.036 14.3 0.2 1 9.6 0.2 2.7 2 1 1 3 3 3 0 AAA domain Snf7 PF03357.21 KEG10808.1 - 1.7e-24 86.3 7.3 2.1e-24 86.1 7.3 1.1 1 0 0 1 1 1 1 Snf7 V-SNARE_C PF12352.8 KEG10808.1 - 0.16 12.3 2.1 8.9 6.7 0.1 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF2155 PF09923.9 KEG10808.1 - 0.19 12.0 0.3 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) UPF0184 PF03670.13 KEG10808.1 - 1 9.8 5.3 1.6 9.2 0.1 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Methyltransf_23 PF13489.6 KEG10809.1 - 9.8e-21 74.3 0.0 2.2e-20 73.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG10809.1 - 5.2e-13 49.4 0.1 7.5e-11 42.5 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEG10809.1 - 1.3e-11 44.3 0.0 8.6e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KEG10809.1 - 2e-10 41.2 0.9 1.2e-06 29.1 0.0 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KEG10809.1 - 4.5e-09 37.0 0.0 0.00062 20.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KEG10809.1 - 9.6e-08 32.0 0.1 1.1e-05 25.2 0.0 2.7 2 2 0 2 2 2 1 Methyltransferase domain RCR PF12273.8 KEG10809.1 - 0.089 13.4 0.9 0.23 12.1 0.9 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TPR_11 PF13414.6 KEG10811.1 - 0.041 13.6 0.0 30 4.4 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 KEG10811.1 - 0.08 13.6 0.3 12 6.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG10811.1 - 0.13 13.1 1.3 1.6e+02 3.6 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF641 PF04859.12 KEG10812.1 - 0.051 13.9 0.1 0.051 13.9 0.1 10.4 4 2 6 10 10 10 0 Plant protein of unknown function (DUF641) Pkinase PF00069.25 KEG10813.1 - 3.2e-63 213.5 0.0 8.5e-36 123.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10813.1 - 3.4e-27 95.3 0.1 3.8e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KEG10813.1 - 0.018 14.4 0.1 0.071 12.5 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG10813.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ycf54 PF10674.9 KEG10813.1 - 0.17 12.2 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) Carn_acyltransf PF00755.20 KEG10815.1 - 1.4e-176 588.6 0.0 1.7e-176 588.3 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FCH PF00611.23 KEG10816.1 - 0.058 13.7 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DAGAT PF03982.13 KEG10817.1 - 3.4e-23 82.0 0.0 6.4e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase SPC25 PF06703.11 KEG10817.1 - 0.23 11.2 5.9 0.061 13.1 0.9 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DAGAT PF03982.13 KEG10818.1 - 2e-23 82.8 0.3 7.4e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol acyltransferase YtpI PF14007.6 KEG10818.1 - 2.1 8.5 7.1 0.54 10.4 0.9 3.4 3 0 0 3 3 3 0 YtpI-like protein DUF5463 PF17551.2 KEG10818.1 - 2.8 7.9 5.7 1.9 8.5 0.8 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5463) SUR7 PF06687.12 KEG10818.1 - 9.6 5.8 19.6 0.58 9.7 0.1 5.0 5 0 0 5 5 5 0 SUR7/PalI family RNA_pol_L_2 PF13656.6 KEG10819.1 - 1e-23 82.9 0.0 1.4e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KEG10819.1 - 2.9e-06 26.6 0.0 4.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CD24 PF14984.6 KEG10820.1 - 0.012 15.8 0.5 0.069 13.4 1.7 1.7 2 0 0 2 2 2 0 CD24 protein DUF543 PF04418.12 KEG10821.1 - 1.8e-20 72.7 0.0 2.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-HC5HC2H PF13771.6 KEG10823.1 - 1.5e-14 54.0 7.5 1.5e-14 54.0 7.5 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KEG10823.1 - 1.5e-12 47.6 11.3 1.5e-12 47.6 11.3 1.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain Neuregulin PF02158.15 KEG10823.1 - 0.44 9.9 12.5 0.62 9.4 12.5 1.2 1 0 0 1 1 1 0 Neuregulin intracellular region zf-ANAPC11 PF12861.7 KEG10823.1 - 6.8 6.8 13.6 0.04 14.0 2.9 2.5 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Robl_LC7 PF03259.17 KEG10824.1 - 0.032 14.0 0.2 0.73 9.7 0.2 2.1 1 1 0 1 1 1 0 Roadblock/LC7 domain LT-IIB PF06453.11 KEG10824.1 - 0.046 13.6 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) 60KD_IMP PF02096.20 KEG10825.1 - 1.1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Pkinase PF00069.25 KEG10826.1 - 4.6e-15 55.7 0.0 8e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10826.1 - 0.00027 20.3 0.0 0.00046 19.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF599 PF04654.12 KEG10827.1 - 0.072 12.5 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF599 ISK_Channel PF02060.15 KEG10827.1 - 0.084 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Rep_2 PF01719.17 KEG10827.1 - 0.14 11.9 0.0 0.16 11.8 0.0 1.0 1 0 0 1 1 1 0 Plasmid replication protein DnaJ PF00226.31 KEG10828.1 - 4.6e-14 52.3 1.8 7.3e-14 51.6 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain Dna2 PF08696.11 KEG10828.1 - 0.16 11.8 0.0 0.72 9.6 0.1 2.0 2 0 0 2 2 2 0 DNA replication factor Dna2 Cgr1 PF03879.14 KEG10829.1 - 0.0065 16.8 23.0 0.0085 16.4 23.0 1.1 1 0 0 1 1 1 1 Cgr1 family FAM178 PF14816.6 KEG10829.1 - 0.096 11.6 3.8 0.11 11.4 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF3619 PF12279.8 KEG10829.1 - 1.3 9.4 4.3 1.4 9.3 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DSPc PF00782.20 KEG10830.1 - 2.1e-21 76.1 0.2 2.8e-21 75.7 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG10830.1 - 0.00036 20.2 0.2 0.00048 19.8 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KEG10830.1 - 0.049 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF5136 PF17199.4 KEG10830.1 - 0.38 10.5 0.1 0.38 10.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF5136) zf-SNAP50_C PF12251.8 KEG10831.1 - 2.9e-40 138.1 0.1 3.9e-40 137.7 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Phage_tail_X PF05489.12 KEG10831.1 - 0.063 12.9 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Phage Tail Protein X WD40 PF00400.32 KEG10832.1 - 1.1e-31 108.3 0.0 7.3e-08 33.0 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Katanin_con80 PF13925.6 KEG10832.1 - 2.1e-20 73.4 1.3 3.1e-20 72.8 1.3 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 KEG10832.1 - 5.3e-14 52.3 0.0 7.1e-05 23.0 0.0 3.8 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG10832.1 - 0.0034 16.4 0.2 3 6.7 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEG10832.1 - 0.0061 15.3 0.2 0.032 12.9 0.1 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KEG10832.1 - 0.1 11.2 0.0 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin WD40_like PF17005.5 KEG10832.1 - 0.24 10.7 0.0 0.52 9.6 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain Sec34 PF04136.15 KEG10833.1 - 0.0002 21.3 0.6 0.0002 21.3 0.6 3.0 3 2 0 3 3 3 1 Sec34-like family ALIX_LYPXL_bnd PF13949.6 KEG10833.1 - 0.00083 18.7 2.6 0.00083 18.7 2.6 2.8 3 1 0 3 3 3 1 ALIX V-shaped domain binding to HIV CENP-F_leu_zip PF10473.9 KEG10833.1 - 0.024 14.7 2.2 0.024 14.7 2.2 4.0 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1181 PF06680.11 KEG10833.1 - 0.025 14.4 0.1 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) V-SNARE PF05008.15 KEG10833.1 - 0.045 14.1 0.9 0.045 14.1 0.9 3.4 4 1 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus TSC22 PF01166.18 KEG10833.1 - 0.048 14.0 0.2 6.3 7.2 0.0 3.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF148 PF02520.17 KEG10833.1 - 0.46 10.6 6.2 0.59 10.3 0.2 3.6 3 2 1 4 4 4 0 Domain of unknown function DUF148 DUF3450 PF11932.8 KEG10833.1 - 0.89 8.8 15.2 2.5 7.4 2.7 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) HisKA_3 PF07730.13 KEG10833.1 - 1.2 9.7 0.0 1.2 9.7 0.0 4.5 4 1 1 5 5 5 0 Histidine kinase Atg14 PF10186.9 KEG10833.1 - 2.2 7.3 11.0 4.4 6.3 4.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KEG10833.1 - 5.1 7.6 25.6 0.62 10.6 1.9 4.0 3 1 1 4 4 4 0 Apg6 coiled-coil region DUF16 PF01519.16 KEG10833.1 - 9.5 6.8 11.1 37 4.9 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function DUF16 ParcG PF10274.9 KEG10834.1 - 1.5e-76 256.6 0.1 1.8e-76 256.4 0.1 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 KEG10834.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 RVT_3 PF13456.6 KEG10835.1 - 0.0014 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Peptidase_C2 PF00648.21 KEG10836.1 - 5.9e-53 179.8 0.0 8.6e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG10836.1 - 1.1e-33 115.7 0.2 6.2e-33 113.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 KEG10837.1 - 1.5e-44 152.2 0.0 1.9e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG10837.1 - 3.3e-29 101.3 0.0 5.8e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 KEG10838.1 - 2.8e-43 148.1 0.0 4e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG10838.1 - 2.9e-31 107.9 0.2 5.6e-31 107.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 KEG10839.1 - 1e-58 198.8 0.0 1.3e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG10839.1 - 8.1e-31 106.5 0.0 1.5e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 KEG10839.1 - 0.0031 17.8 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III DnaJ_C PF01556.18 KEG10840.1 - 5.9e-35 120.5 0.0 7.9e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG10840.1 - 7.7e-23 80.4 0.5 1.4e-22 79.6 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEG10840.1 - 1.5e-06 28.5 23.7 3.3e-06 27.4 23.7 1.6 1 0 0 1 1 1 1 DnaJ central domain Ephrin_rec_like PF07699.13 KEG10840.1 - 0.0048 16.6 0.7 0.0048 16.6 0.7 2.8 2 1 0 2 2 2 1 Putative ephrin-receptor like Anti-TRAP PF15777.5 KEG10840.1 - 7 6.7 17.8 0.92 9.5 4.0 3.1 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_2 PF13639.6 KEG10841.1 - 1.2e-12 47.9 8.5 1.9e-12 47.3 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEG10841.1 - 1.3e-06 28.2 3.9 1.9e-06 27.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEG10841.1 - 2e-06 27.4 2.9 3.7e-06 26.6 2.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEG10841.1 - 8.8e-06 25.5 8.2 1.4e-05 24.8 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG10841.1 - 1.1e-05 25.3 5.8 2e-05 24.5 5.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KEG10841.1 - 9.6e-05 22.6 8.5 0.0003 21.0 8.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KEG10841.1 - 0.00056 19.7 7.0 0.00093 19.0 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG10841.1 - 0.0019 18.0 5.7 0.0035 17.2 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEG10841.1 - 0.015 15.2 7.3 0.024 14.6 7.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain BrnA_antitoxin PF14384.6 KEG10841.1 - 0.026 15.0 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 1 0 BrnA antitoxin of type II toxin-antitoxin system Zn_ribbon_17 PF17120.5 KEG10841.1 - 0.036 13.7 5.5 0.072 12.7 5.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KEG10841.1 - 0.067 13.5 7.0 0.11 12.8 7.0 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KEG10841.1 - 0.47 10.7 3.7 0.97 9.7 3.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KEG10841.1 - 2 8.5 5.3 6.6 6.9 5.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KEG10841.1 - 3.4 7.5 7.3 15 5.5 7.9 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Cmc1 PF08583.10 KEG10842.1 - 0.00046 20.2 2.5 0.00067 19.6 2.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KEG10842.1 - 0.13 12.5 2.0 0.27 11.5 0.5 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 KEG10842.1 - 0.34 11.2 3.6 15 6.0 0.8 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.11 KEG10842.1 - 0.75 10.3 3.6 0.98 9.9 0.9 2.1 1 1 1 2 2 2 0 GCK domain Skp1_POZ PF03931.15 KEG10843.1 - 0.00022 21.3 0.0 0.047 13.9 0.0 2.2 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain TPR_8 PF13181.6 KEG10845.1 - 8e-06 25.7 0.2 0.0057 16.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10845.1 - 0.00038 20.3 0.1 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG10845.1 - 0.00062 20.0 0.7 0.091 13.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 KEG10845.1 - 0.0024 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 KEG10845.1 - 0.005 16.5 0.1 0.0093 15.6 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 KEG10845.1 - 0.011 15.5 0.1 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat IQ PF00612.27 KEG10845.1 - 0.05 13.4 0.2 0.2 11.5 0.2 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif PTPRCAP PF15713.5 KEG10846.1 - 2 8.7 11.4 0.43 10.9 7.0 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 KEG10846.1 - 7.1 4.6 10.5 9.8 4.1 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L30 PF00327.20 KEG10847.1 - 0.00012 21.9 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Rhomboid PF01694.22 KEG10848.1 - 6.2e-07 29.5 1.6 1.2e-06 28.5 1.6 1.5 1 0 0 1 1 1 1 Rhomboid family WD40 PF00400.32 KEG10850.1 - 6.7e-06 26.8 5.3 0.067 14.1 0.2 6.7 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG10850.1 - 6.9e-05 23.1 0.2 0.1 12.9 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 KEG10850.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair NAPRTase PF04095.16 KEG10851.1 - 6.7e-69 232.1 0.0 8.8e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KEG10851.1 - 9.9e-39 132.6 0.0 1.9e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WW PF00397.26 KEG10852.1 - 6.4e-05 23.0 0.8 0.00019 21.5 0.8 1.9 1 0 0 1 1 1 1 WW domain Arm-DNA-bind_1 PF09003.10 KEG10852.1 - 0.023 14.8 0.1 0.07 13.3 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain Sporozoite_P67 PF05642.11 KEG10852.1 - 0.47 8.5 3.2 0.98 7.4 3.2 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KEG10852.1 - 1.3 7.3 31.1 0.69 8.1 6.4 2.3 2 0 0 2 2 2 0 CDC45-like protein Neur_chan_memb PF02932.16 KEG10852.1 - 2.2 8.3 7.6 30 4.6 5.6 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Skp1 PF01466.19 KEG10853.1 - 1.7e-10 40.9 0.0 2.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KEG10853.1 - 0.2 11.8 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Cation_ATPase_C PF00689.21 KEG10854.1 - 1.7e-35 122.4 3.6 1.7e-35 122.4 3.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEG10854.1 - 2.5e-34 118.4 0.9 1.1e-33 116.3 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KEG10854.1 - 5.7e-09 36.6 0.0 0.0088 16.4 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEG10854.1 - 1.4e-05 25.1 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEG10854.1 - 5.9e-05 22.9 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEG10854.1 - 6.6e-05 22.5 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus EF-hand_10 PF14788.6 KEG10854.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 EF hand UPF0093 PF03653.13 KEG10854.1 - 0.1 12.8 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) PSP1 PF04468.12 KEG10855.1 - 4e-13 49.4 1.7 4.4e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Pkinase PF00069.25 KEG10856.1 - 1.3e-45 155.8 0.0 1.9e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10856.1 - 5.3e-27 94.7 0.0 8.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 KEG10856.1 - 1.5e-11 43.9 11.9 5.2e-07 29.3 1.7 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KEG10856.1 - 8e-11 42.0 2.9 4.1e-05 23.8 0.3 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) zf-B_box PF00643.24 KEG10856.1 - 0.00037 20.6 16.9 0.0055 16.8 2.3 2.5 2 0 0 2 2 2 2 B-box zinc finger LRR_9 PF14580.6 KEG10856.1 - 0.0026 17.3 0.4 0.26 10.8 0.1 2.5 1 1 1 2 2 2 1 Leucine-rich repeat zf-UBR PF02207.20 KEG10856.1 - 0.004 17.3 0.7 0.004 17.3 0.7 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) LRR_1 PF00560.33 KEG10856.1 - 0.023 15.2 7.1 1 10.2 0.1 5.1 6 0 0 6 6 4 0 Leucine Rich Repeat APH PF01636.23 KEG10856.1 - 0.044 13.7 1.2 0.47 10.3 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.6 KEG10856.1 - 0.1 12.7 0.0 11 6.4 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Kinase-like PF14531.6 KEG10856.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.16 KEG10856.1 - 2.1 8.7 19.6 0.038 14.3 4.2 3.0 2 0 0 2 2 2 0 C1 domain Cytochrom_C PF00034.21 KEG10857.1 - 0.068 14.3 0.9 24 6.1 0.2 3.0 2 0 0 2 2 2 0 Cytochrome c YokU PF14122.6 KEG10857.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.2 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin Zn_Tnp_IS1595 PF12760.7 KEG10857.1 - 3.4 7.7 14.5 9.2 6.3 2.8 3.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain WD40 PF00400.32 KEG10858.1 - 6.1e-24 83.8 18.1 5.2e-06 27.1 0.4 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG10858.1 - 1.7e-17 63.5 4.7 7.4e-06 26.2 0.1 5.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEG10858.1 - 4.6e-05 23.4 0.0 0.0085 16.0 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KEG10858.1 - 5.3e-05 22.3 0.1 1.4 7.8 0.0 3.6 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KEG10858.1 - 0.12 10.6 0.0 0.25 9.6 0.0 1.4 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 KEG10858.1 - 0.18 10.1 0.3 0.33 9.3 0.3 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family UQ_con PF00179.26 KEG10859.1 - 1.7e-23 82.8 0.1 2.3e-12 46.8 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme SET PF00856.28 KEG10862.1 - 1.3e-11 45.2 0.0 1.9e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.28 KEG10862.1 - 0.00084 19.1 0.2 0.0024 17.6 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG10862.1 - 0.041 14.0 0.2 0.14 12.3 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Ssl1 PF04056.14 KEG10863.1 - 5e-24 85.2 0.0 6.9e-11 42.3 0.0 2.1 1 1 1 2 2 2 2 Ssl1-like VWA_2 PF13519.6 KEG10863.1 - 1.4e-08 35.3 0.0 9.6e-08 32.6 0.0 2.1 1 1 0 2 2 2 1 von Willebrand factor type A domain Vpu PF00558.19 KEG10864.1 - 1.4 8.7 3.5 3.4 7.5 1.6 2.3 2 0 0 2 2 2 0 Vpu protein SpoU_methylase PF00588.19 KEG10865.1 - 2.9e-14 53.4 0.0 3.2e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family FixQ PF05545.11 KEG10865.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_M8 PF01457.16 KEG10866.1 - 6.7e-102 341.9 0.3 8.4e-102 341.5 0.3 1.1 1 0 0 1 1 1 1 Leishmanolysin GP68 PF17469.2 KEG10866.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage protein Gp68 Peptidase_M10 PF00413.24 KEG10866.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M8 PF01457.16 KEG10867.1 - 1.6e-123 413.2 0.0 2.2e-123 412.7 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin G10 PF01125.17 KEG10868.1 - 2.1e-51 173.6 2.6 2.9e-51 173.1 2.6 1.2 1 0 0 1 1 1 1 G10 protein DUF4632 PF15451.6 KEG10868.1 - 0.019 15.1 0.1 0.019 15.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Dynein_light PF01221.18 KEG10870.1 - 4.7e-21 74.9 0.5 5.6e-21 74.7 0.1 1.3 2 0 0 2 2 2 1 Dynein light chain type 1 DUF2332 PF10094.9 KEG10870.1 - 0.016 14.7 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Methyltr_RsmB-F PF01189.17 KEG10871.1 - 5.4e-29 101.3 0.0 3.2e-21 75.9 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KEG10871.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KEG10871.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase PF00102.27 KEG10872.1 - 7.7e-49 166.4 0.0 9.3e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KEG10872.1 - 1.2e-06 28.3 0.0 2.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KEG10872.1 - 9.8e-06 25.7 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KEG10872.1 - 2.8e-05 24.3 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate PDZ_6 PF17820.1 KEG10873.1 - 0.0055 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEG10873.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Choline_transpo PF04515.12 KEG10875.1 - 2.2e-65 221.0 32.2 2.2e-65 221.0 32.2 2.9 1 1 2 3 3 3 1 Plasma-membrane choline transporter DUF5630 PF18632.1 KEG10875.1 - 0.16 11.3 0.2 0.26 10.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5630) TMEM223 PF14640.6 KEG10875.1 - 0.41 10.8 7.9 4.1 7.5 1.2 3.3 2 2 0 2 2 2 0 Transmembrane protein 223 EF-hand_7 PF13499.6 KEG10876.1 - 2e-19 69.8 2.5 1.3e-11 44.8 1.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG10876.1 - 4e-18 63.5 8.3 5.9e-06 25.5 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KEG10876.1 - 4.4e-15 54.3 7.3 0.0021 17.8 0.3 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEG10876.1 - 9.9e-14 50.1 7.4 1e-06 27.9 0.4 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KEG10876.1 - 3.3e-10 39.7 4.6 0.00015 21.5 0.8 3.8 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KEG10876.1 - 4.9e-05 23.6 0.0 0.37 11.1 0.0 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KEG10876.1 - 0.00022 21.3 0.3 0.32 11.2 0.0 3.1 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_4 PF12763.7 KEG10876.1 - 0.0003 20.7 0.5 2.9 7.9 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_13 PF17958.1 KEG10876.1 - 0.082 12.7 0.0 6.9 6.5 0.0 3.2 2 2 1 4 4 4 0 EF-hand domain FG-GAP PF01839.23 KEG10876.1 - 3.1 8.0 6.7 5.9 7.1 0.2 3.0 3 0 0 3 3 3 0 FG-GAP repeat EF-hand_1 PF00036.32 KEG10877.1 - 0.018 14.6 0.0 0.7 9.6 0.0 3.0 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 KEG10877.1 - 0.15 12.1 0.0 0.51 10.4 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 KEG10878.1 - 9e-48 162.9 0.0 1.2e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10878.1 - 5.4e-18 65.2 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEG10878.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG10878.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KEG10878.1 - 0.06 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family 5_3_exonuc_N PF02739.16 KEG10879.1 - 6.7e-28 97.6 0.1 1e-27 97.0 0.1 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KEG10879.1 - 4.1e-20 72.2 0.0 8.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KEG10879.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-MYND PF01753.18 KEG10881.1 - 4.7e-05 23.4 14.3 9.5e-05 22.4 14.3 1.5 1 0 0 1 1 1 1 MYND finger KKLCAg1 PF15204.6 KEG10881.1 - 0.26 11.4 1.6 0.5 10.5 1.6 1.5 1 1 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 ATG16 PF08614.11 KEG10882.1 - 0.11 12.7 21.6 1.3 9.2 4.6 3.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FAA_hydro_N_2 PF18288.1 KEG10882.1 - 3 8.3 5.3 0.78 10.2 0.1 2.8 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 GAS PF13851.6 KEG10882.1 - 3.4 7.0 19.7 0.21 10.9 9.9 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KEG10882.1 - 5 7.4 16.2 3.2 8.0 7.2 3.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 KEG10882.1 - 5.4 6.5 7.3 0.98 8.9 2.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit PUF PF00806.19 KEG10883.1 - 1.4e-50 166.2 5.0 4e-07 29.4 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HrpB1_HrpK PF09613.10 KEG10883.1 - 0.082 12.6 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) CoA_trans PF01144.23 KEG10883.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase MCU PF04678.13 KEG10884.1 - 1.4e-22 80.7 1.6 2.9e-22 79.6 1.6 1.5 1 1 0 1 1 1 1 Mitochondrial calcium uniporter Proteasome PF00227.26 KEG10885.1 - 3.1e-65 219.3 0.0 4.3e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG10885.1 - 3.6e-09 36.1 0.1 8.6e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature IQ PF00612.27 KEG10887.1 - 3.8e-13 48.0 80.3 0.0096 15.6 3.4 14.0 14 0 0 14 14 14 10 IQ calmodulin-binding motif ECSIT_C PF14784.6 KEG10887.1 - 0.15 12.4 5.7 0.26 11.6 0.5 3.7 3 0 0 3 3 3 0 C-terminal domain of the ECSIT protein DUF3176 PF11374.8 KEG10887.1 - 1.7 8.9 4.2 27 5.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) LRR_6 PF13516.6 KEG10888.1 - 5e-14 51.1 11.0 4.2e-05 23.3 0.3 5.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 KEG10888.1 - 2.4e-06 27.8 0.7 0.024 15.1 0.1 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG10888.1 - 0.014 15.8 0.4 2.1e+02 3.1 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KEG10888.1 - 0.045 13.5 0.1 4.2 7.2 0.1 3.0 2 1 0 2 2 2 0 Leucine rich repeat L51_S25_CI-B8 PF05047.16 KEG10889.1 - 0.0082 16.1 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain COG5 PF10392.9 KEG10891.1 - 5.6e-10 39.5 1.6 5.6e-10 39.5 1.6 4.1 5 0 0 5 5 5 1 Golgi transport complex subunit 5 COG2 PF06148.11 KEG10891.1 - 0.00011 22.3 4.2 0.00035 20.6 0.8 3.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 TAN PF11640.8 KEG10891.1 - 0.25 11.4 2.0 10 6.2 0.4 3.8 4 1 0 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF4404 PF14357.6 KEG10891.1 - 5.4 7.7 5.7 36 5.1 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4404) Cas_Cas1 PF01867.16 KEG10893.1 - 0.8 8.8 8.6 0.15 11.2 0.6 2.2 1 1 1 2 2 2 0 CRISPR associated protein Cas1 TSP_NTD PF17804.1 KEG10893.1 - 6.4 7.0 7.3 42 4.3 0.1 2.8 2 1 0 2 2 2 0 Tail specific protease N-terminal domain Arf PF00025.21 KEG10894.1 - 2.7e-06 26.9 0.1 1e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG10894.1 - 4.7e-06 26.8 0.0 8.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEG10894.1 - 1.3e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KEG10894.1 - 1.3e-05 24.5 0.0 0.02 14.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 KEG10894.1 - 0.00054 20.0 0.0 0.00099 19.2 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Ras PF00071.22 KEG10894.1 - 0.011 15.4 0.0 0.028 14.0 0.0 1.7 1 1 0 1 1 1 0 Ras family T2SSE PF00437.20 KEG10894.1 - 0.03 13.4 0.3 0.051 12.6 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Gtr1_RagA PF04670.12 KEG10894.1 - 0.035 13.5 0.2 0.33 10.3 0.0 2.2 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 KEG10894.1 - 0.053 13.2 0.2 0.61 9.7 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KEG10894.1 - 0.071 13.6 0.1 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KEG10894.1 - 0.075 13.6 0.3 0.33 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEG10894.1 - 0.84 10.1 3.8 5.4 7.5 3.8 2.0 1 1 0 1 1 1 0 AAA domain ANAPC2 PF08672.11 KEG10896.1 - 0.068 13.7 0.3 0.74 10.4 0.0 2.5 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 GAS PF13851.6 KEG10897.1 - 0.13 11.6 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ANAPC4_WD40 PF12894.7 KEG10899.1 - 1.5e-11 44.4 0.4 0.15 12.3 0.0 6.4 5 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG10899.1 - 4.9e-11 43.0 20.9 0.69 10.9 0.0 9.4 11 0 0 11 11 11 5 WD domain, G-beta repeat Frtz PF11768.8 KEG10899.1 - 0.016 13.6 0.0 0.031 12.6 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Patatin PF01734.22 KEG10900.1 - 3.8e-21 76.2 0.0 9.5e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.8 KEG10900.1 - 1e-11 44.7 0.3 1.3e-10 41.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) LRR_8 PF13855.6 KEG10902.1 - 1.5e-06 27.8 1.9 3.3e-06 26.7 0.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KEG10902.1 - 1.4e-05 25.3 3.0 0.00012 22.4 0.3 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG10902.1 - 0.035 14.2 2.5 7.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KEG10902.1 - 0.063 13.9 4.4 1.3 9.8 0.8 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat DUF2526 PF10735.9 KEG10902.1 - 0.073 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) HycI PF01750.18 KEG10902.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease Pkinase PF00069.25 KEG10903.1 - 3.3e-48 164.3 0.0 5e-46 157.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10903.1 - 1.7e-32 112.7 0.0 4.7e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NosD PF05048.13 KEG10903.1 - 6e-32 110.8 4.7 5.7e-13 48.7 0.3 3.0 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KEG10903.1 - 2.9e-29 102.0 10.7 8.1e-17 61.5 0.9 3.1 1 1 2 3 3 3 3 Right handed beta helix region zf-B_box PF00643.24 KEG10903.1 - 3.5e-05 23.8 7.1 3.5e-05 23.8 7.1 2.2 2 0 0 2 2 2 1 B-box zinc finger DUF1565 PF07602.11 KEG10903.1 - 0.00022 20.7 1.9 0.00099 18.5 2.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) Kinase-like PF14531.6 KEG10903.1 - 0.011 15.0 0.0 0.047 13.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KEG10903.1 - 0.022 14.7 0.0 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family CEBP_ZZ PF16366.5 KEG10903.1 - 0.13 12.5 3.1 0.51 10.6 3.1 2.0 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Kdo PF06293.14 KEG10903.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BolA PF01722.18 KEG10906.1 - 6e-12 45.7 0.0 7.3e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 KEG10907.1 - 1.5e-37 127.9 1.5 2e-37 127.5 1.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KEG10907.1 - 1.1e-06 28.3 0.5 3.7e-06 26.7 0.5 2.0 1 1 0 1 1 1 1 KOW motif LRR_4 PF12799.7 KEG10909.1 - 5.7e-17 61.5 10.0 6.3e-06 26.4 0.5 4.5 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG10909.1 - 3.5e-11 42.7 10.3 4.3e-06 26.4 1.1 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KEG10909.1 - 1.5e-07 30.9 9.5 0.14 12.3 0.2 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 KEG10909.1 - 3e-06 27.0 5.7 3.6 8.5 0.9 6.0 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 KEG10909.1 - 7.8e-06 25.5 0.2 0.0025 17.4 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Corona_nucleoca PF00937.18 KEG10909.1 - 4.2 6.3 7.2 1.8 7.5 4.2 1.7 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein ZapB PF06005.12 KEG10909.1 - 4.7 7.7 8.3 1.4 9.4 1.5 2.5 2 0 0 2 2 2 0 Cell division protein ZapB RTC PF01137.21 KEG10910.1 - 1.5e-42 145.3 0.1 1.8e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KEG10910.1 - 8.7e-28 96.9 0.1 1.5e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.21 KEG10911.1 - 1.2e-08 35.4 0.0 2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 KEG10912.1 - 1e-58 198.8 0.0 1.2e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10912.1 - 2.6e-19 69.5 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG10912.1 - 9.6e-08 32.2 0.0 8.4e-05 22.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG10912.1 - 0.0033 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KEG10912.1 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KEG10912.1 - 0.043 13.2 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.29 KEG10913.1 - 3.8e-45 154.4 0.2 5.6e-45 153.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KEG10913.1 - 4.6e-17 62.4 0.0 1.8e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 KEG10913.1 - 1.8e-14 54.1 0.1 1.1e-13 51.5 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KEG10913.1 - 3.3e-09 36.4 0.0 7.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UDPGT PF00201.18 KEG10914.1 - 4.2e-15 55.5 0.1 8.6e-13 47.9 0.1 3.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEG10914.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain NUC202 PF08166.12 KEG10916.1 - 0.035 14.2 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 NUC202 domain Yos1 PF08571.10 KEG10917.1 - 2.7e-23 82.0 0.0 3.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.6 KEG10918.1 - 4.6e-14 52.5 19.5 1.2e-07 32.0 7.3 3.5 3 0 0 3 3 3 3 Ring finger domain zf-RING_11 PF17123.5 KEG10918.1 - 5.4e-09 35.6 17.9 0.00017 21.2 7.3 3.8 3 0 0 3 3 3 3 RING-like zinc finger zf-RING_UBOX PF13445.6 KEG10918.1 - 2.2e-07 30.8 15.6 1.4e-05 25.0 0.3 4.1 3 2 1 4 4 4 2 RING-type zinc-finger zf-RING_5 PF14634.6 KEG10918.1 - 1.4e-05 24.9 22.7 0.00015 21.7 7.5 3.6 3 1 0 3 3 3 2 zinc-RING finger domain IQ PF00612.27 KEG10918.1 - 2.4e-05 23.7 2.9 0.00012 21.5 2.9 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4_3 PF13920.6 KEG10918.1 - 0.0023 17.7 17.9 0.051 13.4 4.9 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG10918.1 - 0.0097 15.8 21.8 0.019 14.9 6.4 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG10918.1 - 0.023 14.5 24.4 0.063 13.1 7.6 4.4 3 2 0 3 3 3 0 Prokaryotic RING finger family 4 DUF4048 PF13257.6 KEG10918.1 - 0.098 12.5 6.4 0.16 11.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Zn_ribbon_17 PF17120.5 KEG10918.1 - 0.13 11.9 9.2 0.47 10.1 4.2 2.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Sporozoite_P67 PF05642.11 KEG10918.1 - 0.65 8.0 3.5 0.87 7.6 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_ligase_ZBD PF03119.16 KEG10918.1 - 3.7 7.7 9.9 6.2 6.9 0.2 4.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-rbx1 PF12678.7 KEG10918.1 - 3.8 7.9 29.0 6.2 7.2 5.2 4.5 3 2 0 3 3 3 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KEG10918.1 - 8.1 6.4 32.7 4.3 7.3 13.6 5.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 KEG10920.1 - 0.011 15.8 1.7 0.4 10.7 0.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Amastin PF07344.11 KEG10921.1 - 0.044 13.6 15.8 0.067 13.0 15.8 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein 7tm_1 PF00001.21 KEG10921.1 - 3.5 6.9 9.1 4.8 6.4 9.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF975 PF06161.11 KEG10921.1 - 6.4 6.5 9.5 11 5.7 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF975) RRM_1 PF00076.22 KEG10923.1 - 2.2e-23 81.8 0.5 6.8e-14 51.4 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG10923.1 - 1e-05 25.6 0.7 0.15 12.2 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif FAD_binding_1 PF00667.20 KEG10924.1 - 2.6e-32 112.2 0.0 4.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEG10924.1 - 3.1e-19 69.6 0.1 2e-18 67.0 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEG10924.1 - 1.2e-06 29.1 0.0 3.2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG10924.1 - 0.00014 22.1 0.0 0.00077 19.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cortex-I_coil PF09304.10 KEG10925.1 - 0.064 13.5 0.9 0.13 12.5 0.9 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil DHHC PF01529.20 KEG10927.1 - 2.3e-27 95.7 9.6 2.3e-27 95.7 9.6 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4149 PF13664.6 KEG10927.1 - 9.9 6.6 10.1 0.53 10.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF2181 PF10223.9 KEG10928.1 - 2.1e-13 50.3 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) P34-Arc PF04045.14 KEG10929.1 - 1.7e-27 96.7 0.0 2.1e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc CxC7 PF18866.1 KEG10930.1 - 0.016 15.3 0.1 0.24 11.6 0.0 2.4 3 0 0 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases PNP_UDP_1 PF01048.20 KEG10931.1 - 8.3e-49 166.0 0.4 9.6e-49 165.7 0.4 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PP-binding_2 PF14573.6 KEG10931.1 - 0.016 15.4 0.0 0.046 14.0 0.0 1.7 1 1 0 1 1 1 0 Acyl-carrier Mito_carr PF00153.27 KEG10932.1 - 1.4e-23 82.6 4.6 2.3e-09 37.0 0.3 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3624 PF12292.8 KEG10932.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) Serine_protease PF18405.1 KEG10932.1 - 0.38 9.9 3.2 1.3 8.1 0.2 2.3 1 1 0 2 2 2 0 Gammaproteobacterial serine protease RRM_1 PF00076.22 KEG10933.1 - 3.1e-09 36.5 0.0 8.6e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amelotin PF15757.5 KEG10933.1 - 0.64 9.6 3.5 1.3 8.6 3.5 1.5 1 0 0 1 1 1 0 Amelotin PPL5 PF18168.1 KEG10933.1 - 7.1 5.8 12.0 0.23 10.7 5.6 1.7 2 0 0 2 2 2 0 Prim-pol family 5 CH_2 PF06294.11 KEG10934.1 - 1.9e-25 88.8 0.0 7e-25 87.0 0.0 2.0 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KEG10934.1 - 1.8e-05 24.5 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Med3 PF11593.8 KEG10934.1 - 0.019 14.2 2.5 0.19 10.9 1.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.19 KEG10934.1 - 0.52 10.9 6.1 2.2 8.9 6.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DnaJ PF00226.31 KEG10935.1 - 1.9e-06 27.9 0.1 3.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2617 PF10936.8 KEG10941.1 - 0.0056 16.8 1.0 0.98 9.5 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function DUF2617 AMP-binding PF00501.28 KEG10943.1 - 1.2e-57 195.4 0.2 1.6e-57 195.0 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEG10943.1 - 0.00038 21.4 0.5 0.0016 19.4 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 KEG10943.1 - 0.0091 16.2 0.2 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 FeoA domain Radial_spoke PF04712.12 KEG10944.1 - 1e-128 430.4 24.9 9.7e-99 331.5 9.1 2.9 1 1 2 3 3 3 2 Radial spokehead-like protein Pkinase PF00069.25 KEG10945.1 - 5.6e-78 261.9 0.0 9.9e-78 261.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10945.1 - 3.5e-44 151.0 0.0 7.4e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 KEG10945.1 - 2.3e-10 40.1 0.0 0.00044 20.2 0.0 5.2 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 KEG10945.1 - 2.9e-06 26.8 0.1 9.7e-06 25.1 0.1 1.8 1 1 1 2 2 2 1 Kinase-like HEAT PF02985.22 KEG10945.1 - 2.2e-05 24.3 0.0 3.3 8.2 0.0 5.7 6 1 1 7 7 5 1 HEAT repeat HEAT_2 PF13646.6 KEG10945.1 - 2.4e-05 24.6 0.1 0.0034 17.7 0.1 3.8 4 1 1 5 5 4 2 HEAT repeats Pkinase_fungal PF17667.1 KEG10945.1 - 6.9e-05 21.8 0.0 0.00016 20.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase HEAT_EZ PF13513.6 KEG10945.1 - 0.00015 22.2 0.1 0.16 12.5 0.0 4.3 2 1 1 3 3 3 2 HEAT-like repeat Kdo PF06293.14 KEG10945.1 - 0.0004 19.8 0.1 0.00097 18.5 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG10945.1 - 0.0042 17.0 0.0 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG10945.1 - 0.0055 15.7 0.2 0.014 14.3 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KEG10945.1 - 0.0099 15.5 5.6 0.015 14.9 1.7 2.6 2 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KEG10945.1 - 0.013 15.1 0.4 0.035 13.7 0.2 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KEG10945.1 - 0.032 13.7 0.2 0.067 12.7 0.2 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 KEG10945.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3947 PF13135.6 KEG10945.1 - 0.15 12.3 0.7 2.2 8.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Alba PF01918.21 KEG10946.1 - 4e-13 49.0 0.6 6.8e-13 48.2 0.6 1.3 1 0 0 1 1 1 1 Alba Mad3_BUB1_I_2 PF17014.5 KEG10946.1 - 0.00046 20.3 0.1 0.00064 19.8 0.1 1.5 1 1 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Rpp20 PF12328.8 KEG10946.1 - 0.0026 17.7 0.3 0.0026 17.7 0.3 2.1 1 1 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KEG10947.1 - 1e-16 60.4 1.3 5.7e-16 58.1 0.2 2.0 2 0 0 2 2 2 1 Alba Rpp20 PF12328.8 KEG10947.1 - 0.00076 19.4 1.8 0.0058 16.6 0.0 2.1 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P CYTH PF01928.21 KEG10947.1 - 0.038 13.9 0.2 0.038 13.9 0.2 1.1 1 0 0 1 1 1 0 CYTH domain NAD_binding_1 PF00175.21 KEG10949.1 - 7.4e-28 97.4 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG10949.1 - 3.2e-27 94.8 0.0 4.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEG10949.1 - 9.4e-06 25.8 0.0 0.00046 20.4 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain HECT PF00632.25 KEG10951.1 - 0.025 14.0 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 0 HECT-domain (ubiquitin-transferase) AAA PF00004.29 KEG10952.1 - 1.1e-41 142.3 0.0 2.4e-41 141.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG10952.1 - 2.2e-09 37.0 0.5 5e-09 35.8 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KEG10952.1 - 3.8e-08 33.2 0.2 8.2e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KEG10952.1 - 8.8e-07 29.2 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_OB_N PF17758.1 KEG10952.1 - 2.5e-05 23.8 0.0 7.4e-05 22.3 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 KEG10952.1 - 4.2e-05 24.0 0.0 0.0036 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEG10952.1 - 6.7e-05 22.9 0.1 0.00025 21.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG10952.1 - 9.8e-05 22.6 0.4 0.028 14.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KEG10952.1 - 0.00021 20.5 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KEG10952.1 - 0.0003 20.5 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEG10952.1 - 0.0049 17.0 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG10952.1 - 0.0052 17.3 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KEG10952.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEG10952.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KEG10952.1 - 0.017 14.5 0.2 0.59 9.4 0.1 2.3 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 KEG10952.1 - 0.018 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KEG10952.1 - 0.026 14.9 0.1 0.083 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEG10952.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KEG10952.1 - 0.036 14.0 0.3 0.67 9.9 0.3 2.4 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KEG10952.1 - 0.038 14.2 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEG10952.1 - 0.05 13.3 0.5 0.22 11.2 0.3 2.3 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 KEG10952.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 KEG10952.1 - 0.096 11.9 0.3 0.21 10.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KEG10952.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KEG10952.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KEG10952.1 - 0.14 11.9 0.1 0.37 10.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG10952.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA-synt_1 PF00133.22 KEG10954.1 - 6.8e-29 100.6 0.0 5.4e-17 61.3 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEG10954.1 - 2e-18 66.3 0.0 4.3e-09 35.6 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEG10954.1 - 9.8e-15 54.8 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEG10954.1 - 1.8e-06 27.5 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain SpoU_methylase PF00588.19 KEG10956.1 - 1.6e-22 80.2 0.0 4e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family WW PF00397.26 KEG10957.1 - 3.8e-09 36.5 0.5 6.5e-09 35.7 0.5 1.3 1 0 0 1 1 1 1 WW domain Transferase PF02458.15 KEG10957.1 - 1.2 7.6 10.5 0.16 10.6 0.2 2.6 2 1 0 2 2 2 0 Transferase family DUF3450 PF11932.8 KEG10957.1 - 3.4 6.9 55.3 0.081 12.2 4.8 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KEG10957.1 - 4.2 7.9 69.7 1.3 9.6 24.2 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region Sod_Fe_C PF02777.18 KEG10958.1 - 5.1e-30 103.7 1.9 5.6e-30 103.5 0.2 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEG10958.1 - 1.9e-16 60.3 0.1 4.2e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Complex1_LYR PF05347.15 KEG10959.1 - 0.0015 18.6 0.8 0.0045 17.0 0.8 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) MAT1-1-2 PF17043.5 KEG10959.1 - 0.1 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function zf_UBZ PF18439.1 KEG10960.1 - 0.0055 16.3 2.4 0.013 15.1 0.3 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf_C2HC_14 PF18574.1 KEG10960.1 - 0.035 13.9 0.8 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain MAT1 PF06391.13 KEG10960.1 - 5.4 6.8 28.9 17 5.2 0.2 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DAO PF01266.24 KEG10965.1 - 1.9e-46 159.3 0.0 3.1e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEG10965.1 - 7.9e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEG10965.1 - 0.0063 15.8 0.0 0.022 14.0 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEG10965.1 - 0.011 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KEG10965.1 - 0.044 12.6 0.2 0.064 12.1 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.15 KEG10965.1 - 0.05 12.1 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 KEG10965.1 - 0.087 11.9 0.3 0.14 11.2 0.3 1.6 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KEG10965.1 - 0.11 11.7 0.1 0.38 9.9 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Reprolysin_5 PF13688.6 KEG10965.1 - 0.13 12.4 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 TrkA_N PF02254.18 KEG10965.1 - 0.13 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain SEP PF08059.13 KEG10967.1 - 3.1e-08 34.1 0.0 1.8e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KEG10967.1 - 2e-05 24.7 0.0 4.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain TPR_MLP1_2 PF07926.12 KEG10967.1 - 0.05 13.7 7.2 0.089 12.8 7.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DAPDH_C PF16654.5 KEG10967.1 - 0.1 12.5 0.6 3.8 7.3 0.3 2.4 2 1 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Cep57_MT_bd PF06657.13 KEG10967.1 - 0.79 10.2 5.3 1.5 9.4 5.3 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TylF PF05711.11 KEG10968.1 - 3.2e-32 111.8 0.0 3.9e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 KEG10968.1 - 2.2e-12 47.9 0.4 1.2e-11 45.5 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 KEG10968.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase SF1-HH PF16275.5 KEG10969.1 - 0.00026 21.3 0.1 0.00059 20.2 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KEG10969.1 - 0.00039 20.2 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 KH domain SPX PF03105.19 KEG10969.1 - 0.008 16.1 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 SPX domain AIRS_C PF02769.22 KEG10970.1 - 6.1e-21 75.2 0.0 1.3e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KEG10970.1 - 1.8e-07 31.7 0.1 4.2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain BCS1_N PF08740.11 KEG10971.1 - 1.5e-26 93.6 0.5 2.2e-26 93.0 0.5 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KEG10971.1 - 1e-08 35.7 0.0 0.00048 20.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG10971.1 - 0.0032 17.9 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain FXR_C1 PF16096.5 KEG10971.1 - 0.023 14.9 2.4 0.053 13.7 2.4 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 AAA_11 PF13086.6 KEG10971.1 - 0.042 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEG10971.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KEG10971.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KEG10971.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Pribosyltran_N PF13793.6 KEG10972.1 - 8.4e-40 135.3 0.1 2.9e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEG10972.1 - 3e-29 102.4 3.5 4.3e-29 101.9 1.8 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEG10972.1 - 4.6e-16 58.7 0.4 8.4e-16 57.9 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEG10972.1 - 0.00038 20.0 0.2 0.00082 18.9 0.2 1.6 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pyr_redox_2 PF07992.14 KEG10973.1 - 1.2e-50 172.4 0.0 1.5e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEG10973.1 - 9.2e-09 35.7 2.8 2.2e-08 34.5 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG10973.1 - 0.0025 18.0 0.1 0.28 11.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEG10973.1 - 0.095 12.3 1.9 5 6.6 0.1 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEG10973.1 - 0.1 11.8 0.1 0.59 9.3 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3323 PF11796.8 KEG10973.1 - 0.34 10.8 2.7 0.74 9.7 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) mRNA_cap_enzyme PF01331.19 KEG10974.1 - 1.1e-09 38.3 0.2 3.9e-09 36.6 0.2 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KEG10974.1 - 3.5e-07 30.8 0.0 9.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Zeta_toxin PF06414.12 KEG10974.1 - 0.00014 21.2 0.0 0.077 12.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ADK PF00406.22 KEG10974.1 - 0.00052 20.2 0.0 0.0019 18.3 0.0 1.8 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 KEG10974.1 - 0.00093 19.6 0.0 0.0022 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG10974.1 - 0.0026 18.3 0.0 0.015 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KEG10974.1 - 0.0098 15.6 0.1 0.82 9.3 0.1 2.3 1 1 1 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 KEG10974.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG10974.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PAM2 PF07145.15 KEG10974.1 - 0.26 11.1 3.8 0.64 9.8 3.8 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region LicD PF04991.13 KEG10975.1 - 5.9e-10 39.7 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 LicD family CPSF_A PF03178.15 KEG10976.1 - 1.2e-61 208.8 0.0 2.3e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KEG10976.1 - 2.3e-18 66.1 0.0 1.8e-17 63.2 0.0 2.3 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term NOA36 PF06524.12 KEG10976.1 - 4.9 6.4 4.8 8.2 5.6 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_C97 PF05903.14 KEG10977.1 - 3.1e-19 69.3 0.1 4.9e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain GGDEF_2 PF17853.1 KEG10977.1 - 0.0079 16.4 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 GGDEF-like domain DUF3872 PF12988.7 KEG10977.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) DUF3782 PF12644.7 KEG10978.1 - 0.41 10.8 4.6 0.27 11.4 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) WLM PF08325.10 KEG10979.1 - 4.7e-52 176.8 1.0 1.7e-34 119.5 1.4 3.1 2 1 0 2 2 2 2 WLM domain zf-RanBP PF00641.18 KEG10979.1 - 5.9e-06 25.5 21.6 0.0076 15.6 0.2 5.0 5 0 0 5 5 5 4 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KEG10979.1 - 5.4e-05 23.3 5.0 0.0055 16.8 0.4 2.5 3 0 0 3 3 3 2 Protein of unknown function DUF45 PHD_2 PF13831.6 KEG10979.1 - 0.85 9.2 13.5 4.7 6.9 0.2 4.4 4 0 0 4 4 4 0 PHD-finger Pep_deformylase PF01327.21 KEG10982.1 - 4.2e-21 75.2 0.0 5.3e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Fer4 PF00037.27 KEG10982.1 - 0.066 13.1 1.0 0.11 12.3 1.0 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain DnaJ PF00226.31 KEG10984.1 - 7e-23 80.5 0.8 1.3e-22 79.7 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain Promethin PF16015.5 KEG10984.1 - 0.00031 20.6 7.1 0.00031 20.6 7.1 4.0 2 1 1 3 3 3 1 Promethin Tmemb_185A PF10269.9 KEG10984.1 - 0.00067 19.4 8.7 0.00067 19.4 8.7 2.7 2 1 1 3 3 3 1 Transmembrane Fragile-X-F protein TRAP_alpha PF03896.16 KEG10984.1 - 0.078 12.2 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-HC2 PF13490.6 KEG10984.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative zinc-finger E2_bind PF08825.10 KEG10985.1 - 0.18 11.9 2.5 0.66 10.2 0.2 2.9 2 0 0 2 2 2 0 E2 binding domain Aminotran_1_2 PF00155.21 KEG10986.1 - 0.014 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Reovirus_M2 PF05993.12 KEG10986.1 - 0.09 10.9 0.0 0.15 10.1 0.0 1.3 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) DDRGK PF09756.9 KEG10987.1 - 8.1e-21 74.5 37.2 1.3e-18 67.3 0.4 3.5 1 1 3 4 4 4 2 DDRGK domain VirE PF05272.11 KEG10987.1 - 0.018 14.8 0.3 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 Virulence-associated protein E SID-1_RNA_chan PF13965.6 KEG10987.1 - 0.2 10.1 0.6 0.51 8.7 0.0 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Pkinase PF00069.25 KEG10988.1 - 9.7e-35 120.2 0.0 2e-29 102.7 0.0 3.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10988.1 - 1.2e-16 60.8 0.0 2.9e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG10988.1 - 0.0048 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Doppel PF11466.8 KEG10991.1 - 0.039 13.6 0.5 0.075 12.7 0.5 1.5 1 0 0 1 1 1 0 Prion-like protein Doppel Gpr1_Fun34_YaaH PF01184.19 KEG10992.1 - 5e-37 127.5 19.2 5.9e-37 127.3 19.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 KEG10993.1 - 2.4e-36 125.3 8.0 2.9e-36 125.0 8.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.15 KEG10993.1 - 0.39 11.2 12.2 4.7 7.7 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) zf-CCCH_4 PF18044.1 KEG10994.1 - 6.3e-10 38.6 4.8 6.3e-10 38.6 4.8 1.7 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 KEG10994.1 - 2.9e-07 31.2 0.2 2.9e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 KEG10994.1 - 3.2e-06 27.0 7.4 3.2e-06 27.0 7.4 2.8 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 KEG10994.1 - 1.6e-05 24.6 10.2 4.2e-05 23.3 2.8 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KEG10994.1 - 0.0013 19.0 0.2 0.82 9.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEG10994.1 - 1.6 9.3 12.3 2.8 8.6 3.7 2.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger SET PF00856.28 KEG10995.1 - 0.0016 18.9 0.0 0.0026 18.2 0.0 1.5 1 1 0 1 1 1 1 SET domain Chordopox_G3 PF06129.12 KEG10996.1 - 0.12 13.0 0.1 0.27 12.0 0.0 1.5 2 0 0 2 2 2 0 Chordopoxvirus G3 protein OAD_gamma PF04277.13 KEG10996.1 - 0.31 11.6 0.0 0.31 11.6 0.0 3.0 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TTL PF03133.15 KEG10997.1 - 1.2e-69 234.7 0.0 1.8e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG10997.1 - 0.00026 20.4 0.1 0.0023 17.2 0.0 2.3 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KEG10997.1 - 0.0086 15.4 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Pkinase PF00069.25 KEG10998.1 - 1.9e-56 191.3 0.0 3.1e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG10998.1 - 6.1e-36 124.0 0.0 9.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG10998.1 - 2.9e-10 40.6 0.1 7.5e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KEG10998.1 - 5.3e-07 29.2 0.0 9.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KEG10998.1 - 0.024 15.0 1.2 0.18 12.3 1.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 KEG10998.1 - 0.041 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain MCM PF00493.23 KEG10999.1 - 1.1e-61 207.8 0.0 1.9e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KEG10999.1 - 6.6e-15 55.3 0.1 1.5e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KEG10999.1 - 1.8e-11 43.9 0.9 5e-11 42.5 0.9 1.7 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 KEG10999.1 - 3.7e-07 29.7 0.1 4.2e-05 23.0 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEG10999.1 - 6.6e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEG10999.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Raptor_N PF14538.6 KEG10999.1 - 0.079 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Sigma54_activat PF00158.26 KEG10999.1 - 0.087 12.5 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad51 PF08423.11 KEG11002.1 - 6.5e-124 412.2 0.1 9.8e-124 411.7 0.1 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KEG11002.1 - 5e-14 52.4 0.2 6.7e-14 52.0 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KEG11002.1 - 9.5e-07 28.4 0.1 2.1e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KEG11002.1 - 9.1e-06 26.2 0.6 4.3e-05 24.0 0.7 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 KEG11002.1 - 1.1e-05 25.1 0.1 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEG11002.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KEG11002.1 - 0.027 13.8 0.7 0.058 12.7 0.1 1.9 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain TPR_2 PF07719.17 KEG11003.1 - 4.2e-14 51.4 10.7 2.5e-05 24.1 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG11003.1 - 3.1e-13 48.9 5.8 8e-05 22.3 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG11003.1 - 1e-11 44.3 8.9 1.1e-07 31.4 2.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 KEG11003.1 - 2.7e-10 40.7 16.6 2.7e-06 27.9 6.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11003.1 - 7.6e-10 38.2 1.1 0.038 14.2 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEG11003.1 - 1.5e-06 28.6 6.7 5e-05 23.7 3.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG11003.1 - 1.5e-06 28.4 12.4 0.0018 18.5 7.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat UPF0121 PF03661.13 KEG11003.1 - 2.8e-06 26.9 8.5 3.7e-06 26.5 8.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_14 PF13428.6 KEG11003.1 - 4.2e-06 27.1 11.3 0.04 14.7 1.6 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEG11003.1 - 2.3e-05 24.1 11.9 0.45 10.4 1.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG11003.1 - 3.9e-05 23.4 3.7 0.083 13.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG11003.1 - 6.4e-05 23.1 3.1 0.0019 18.5 1.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG11003.1 - 0.076 13.2 8.9 0.15 12.3 2.5 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KEG11003.1 - 0.35 10.4 1.5 38 3.9 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR PV-1 PF06637.11 KEG11004.1 - 0.98 8.2 22.0 0.1 11.4 17.3 1.6 1 1 0 1 1 1 0 PV-1 protein (PLVAP) SUIM_assoc PF16619.5 KEG11004.1 - 1.4 9.0 16.1 0.11 12.6 2.3 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_18 PF13238.6 KEG11004.1 - 5.5 7.6 9.5 2.7 8.6 6.1 2.0 1 1 0 2 2 2 0 AAA domain MIF4G PF02854.19 KEG11005.1 - 1.9e-11 44.1 3.7 3e-11 43.4 0.6 2.4 2 0 0 2 2 2 1 MIF4G domain CaMKII_AD PF08332.10 KEG11005.1 - 0.0029 17.7 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain TFIIA PF03153.13 KEG11005.1 - 0.34 10.8 25.8 0.12 12.3 8.4 2.7 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 KEG11005.1 - 0.66 10.6 1.9 7.3 7.2 0.1 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Ndc1_Nup PF09531.10 KEG11005.1 - 2.5 6.7 14.4 0.33 9.6 4.8 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Connexin PF00029.19 KEG11005.1 - 5.8 6.6 9.6 2.2 8.0 0.1 2.6 3 0 0 3 3 3 0 Connexin Actin PF00022.19 KEG11006.1 - 7.7e-87 291.5 0.0 1.5e-42 145.6 0.0 2.0 1 1 1 2 2 2 2 Actin EF-hand_7 PF13499.6 KEG11007.1 - 0.018 15.5 0.7 0.32 11.5 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KEG11007.1 - 0.082 12.5 0.0 1.4 8.7 0.0 2.8 3 0 0 3 3 3 0 EF hand NIF PF03031.18 KEG11008.1 - 1.7e-07 31.2 0.0 2.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.8 KEG11008.1 - 0.03 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DnaT PF17948.1 KEG11008.1 - 0.18 11.5 0.0 0.49 10.1 0.0 1.7 2 0 0 2 2 2 0 DnaT DNA-binding domain WH2 PF02205.20 KEG11009.1 - 0.0075 16.1 3.0 0.6 10.0 0.2 3.3 4 0 0 4 4 4 1 WH2 motif Med9 PF07544.13 KEG11009.1 - 0.019 15.0 1.4 0.019 15.0 1.4 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DLP_helical PF18709.1 KEG11009.1 - 0.027 13.7 1.9 1.3 8.1 0.1 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain SUIM_assoc PF16619.5 KEG11009.1 - 0.094 12.8 0.6 0.094 12.8 0.6 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2058 PF09831.9 KEG11009.1 - 0.16 12.2 6.4 1 9.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DivIC PF04977.15 KEG11009.1 - 9.3 6.1 8.0 0.46 10.3 0.8 2.3 2 0 0 2 2 2 0 Septum formation initiator RabGAP-TBC PF00566.18 KEG11010.1 - 1.2e-05 25.1 0.3 1.2e-05 25.1 0.3 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain COMM_domain PF07258.14 KEG11011.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.7 1 1 0 1 1 1 0 COMM domain 2OG-FeII_Oxy PF03171.20 KEG11012.1 - 0.00018 22.0 0.0 0.00071 20.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.22 KEG11012.1 - 0.11 12.9 0.0 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Thioesterase superfamily Actin PF00022.19 KEG11013.1 - 7.4e-88 294.9 0.0 2.8e-56 190.9 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KEG11013.1 - 0.01 14.7 0.0 0.029 13.2 0.0 1.8 2 1 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 KEG11013.1 - 0.15 12.5 0.0 1.3 9.5 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA DUF1796 PF08795.10 KEG11014.1 - 6.6e-51 172.6 0.0 1.2e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.18 KEG11015.1 - 3.7e-80 268.7 0.6 5.4e-80 268.2 0.6 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KEG11015.1 - 8.2e-05 22.9 0.5 0.21 12.0 0.1 2.9 1 1 1 2 2 2 2 NOP5NT (NUC127) domain DUF3306 PF11748.8 KEG11015.1 - 0.039 14.8 0.1 0.14 13.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RHH_6 PF16762.5 KEG11015.1 - 2.3 8.9 4.6 23 5.7 0.3 3.6 3 1 1 4 4 4 0 Ribbon-helix-helix domain VASt PF16016.5 KEG11016.1 - 1.8e-08 34.9 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Ribosomal_L27e PF01777.18 KEG11017.1 - 6.3e-25 87.3 2.5 1e-24 86.7 2.5 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KEG11017.1 - 6.4e-07 29.1 1.4 7.1e-07 29.0 0.4 1.6 2 0 0 2 2 2 1 KOW motif RPN13_C PF16550.5 KEG11018.1 - 0.15 12.3 0.8 6.3 7.0 0.2 2.7 2 0 0 2 2 2 0 UCH-binding domain Pardaxin PF07425.11 KEG11020.1 - 0.15 11.7 0.2 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 Pardaxin Ribosomal_L27e PF01777.18 KEG11021.1 - 6.3e-25 87.3 2.5 1e-24 86.7 2.5 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KEG11021.1 - 6.4e-07 29.1 1.4 7.1e-07 29.0 0.4 1.6 2 0 0 2 2 2 1 KOW motif Sod_Fe_C PF02777.18 KEG11023.1 - 5.4e-41 138.9 0.6 6e-41 138.8 0.6 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain GH101_N PF17995.1 KEG11023.1 - 0.0027 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Endo-alpha-N-acetylgalactosaminidase N-terminal GSHPx PF00255.19 KEG11024.1 - 3.5e-27 94.1 0.0 4.1e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 KEG11024.1 - 0.0038 17.0 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEG11024.1 - 0.0049 16.8 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Nif11 PF07862.11 KEG11024.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Nif11 domain Glyco_transf_88 PF16849.5 KEG11024.1 - 0.078 11.9 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 88 Sybindin PF04099.12 KEG11025.1 - 1.5e-22 80.0 0.0 1.8e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KEG11025.1 - 1.4e-08 34.9 0.0 1.6e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ACOX PF01756.19 KEG11025.1 - 0.11 12.0 0.0 0.61 9.6 0.0 1.9 1 1 1 2 2 2 0 Acyl-CoA oxidase TraH_2 PF06871.11 KEG11026.1 - 0.39 10.3 1.6 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 TraH_2 Aa_trans PF01490.18 KEG11027.1 - 2.6e-56 191.1 37.7 3.1e-56 190.8 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG11027.1 - 5.7e-09 35.5 18.1 5.7e-09 35.5 18.1 2.5 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family Rhodanese PF00581.20 KEG11028.1 - 8.8e-11 42.3 0.0 1e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain FA_desaturase PF00487.24 KEG11029.1 - 2e-21 77.0 23.5 2.8e-21 76.5 23.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KEG11029.1 - 0.0027 17.2 0.1 0.0048 16.4 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF3287 PF11690.8 KEG11031.1 - 0.024 14.4 2.6 0.029 14.1 0.5 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Cnn_1N PF07989.11 KEG11031.1 - 0.026 14.7 2.6 0.48 10.6 0.3 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FlxA PF14282.6 KEG11031.1 - 0.077 13.0 1.7 0.23 11.4 1.6 1.9 1 1 0 1 1 1 0 FlxA-like protein PCuAC PF04314.13 KEG11031.1 - 0.089 12.6 0.1 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Copper chaperone PCu(A)C Med9 PF07544.13 KEG11031.1 - 0.1 12.7 3.5 0.1 12.7 0.9 2.3 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Nas2_N PF18265.1 KEG11031.1 - 1.5 8.8 4.7 2.5 8.1 0.3 2.9 3 0 0 3 3 3 0 Nas2 N_terminal domain DUF5446 PF17522.2 KEG11031.1 - 2.2 8.5 6.6 3.3 7.9 0.9 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5446) Spc24 PF08286.11 KEG11031.1 - 4.4 7.6 6.8 0.99 9.7 3.1 1.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 COMM_domain PF07258.14 KEG11032.1 - 1.4e-06 28.3 0.0 1.7e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 COMM domain NOA36 PF06524.12 KEG11033.1 - 8.3 5.6 10.7 24 4.1 10.7 1.7 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 KEG11034.1 - 1.1e-58 198.7 0.0 1.9e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11034.1 - 1.2e-38 132.9 0.0 1.8e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 KEG11034.1 - 4.2e-07 30.0 0.0 2e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold 7TM_GPCR_Srh PF10318.9 KEG11034.1 - 0.00083 18.5 1.0 0.0018 17.4 1.0 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Pkinase_fungal PF17667.1 KEG11034.1 - 0.0012 17.8 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG11034.1 - 0.0035 16.7 0.0 0.93 8.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS_9 PF13426.7 KEG11034.1 - 0.0085 16.3 0.0 0.2 11.9 0.0 2.7 3 0 0 3 3 3 1 PAS domain RIH_assoc PF08454.11 KEG11034.1 - 0.026 14.4 3.5 0.031 14.1 0.5 2.4 2 0 0 2 2 2 0 RyR and IP3R Homology associated APH PF01636.23 KEG11034.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_4 PF08448.10 KEG11034.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold Ank_2 PF12796.7 KEG11035.1 - 2.6e-08 34.3 0.0 0.0037 17.8 0.0 3.9 2 2 2 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG11035.1 - 3.2e-08 33.7 0.3 0.013 15.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG11035.1 - 6.7e-08 32.2 0.2 0.067 13.8 0.0 5.9 5 1 1 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 KEG11035.1 - 7.9e-05 23.1 1.4 0.0017 18.9 0.0 3.8 4 2 0 4 4 4 1 Ankyrin repeats (many copies) RDV-p3 PF09231.10 KEG11035.1 - 0.18 9.5 0.0 0.24 9.1 0.0 1.1 1 0 0 1 1 1 0 Rice dwarf virus p3 Fis1_TPR_C PF14853.6 KEG11036.1 - 0.021 14.9 0.5 5.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat RAG1_imp_bd PF12560.8 KEG11036.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 RAG1 importin binding TPR_19 PF14559.6 KEG11036.1 - 0.35 11.4 3.7 5 7.7 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat BLOC1_2 PF10046.9 KEG11037.1 - 1.1e-17 64.1 2.1 1.4e-17 63.7 2.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPO PF05929.11 KEG11037.1 - 0.024 14.3 2.8 0.03 14.0 2.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase VPS28 PF03997.12 KEG11037.1 - 0.027 14.1 0.4 0.033 13.8 0.4 1.2 1 0 0 1 1 1 0 VPS28 protein Antirestrict PF03230.13 KEG11037.1 - 0.061 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein CK2S PF15011.6 KEG11037.1 - 0.089 12.7 2.6 0.14 12.0 2.5 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate Baculo_PEP_C PF04513.12 KEG11037.1 - 0.11 12.5 0.9 0.39 10.7 0.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3958 PF13125.6 KEG11037.1 - 0.21 11.8 2.8 0.27 11.5 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) NPV_P10 PF05531.12 KEG11037.1 - 0.25 11.8 1.2 0.35 11.4 0.4 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 KEG11037.1 - 0.33 11.6 3.4 2.4 8.8 1.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Spectrin PF00435.21 KEG11037.1 - 0.33 11.4 4.5 6.3 7.3 0.6 2.3 1 1 1 2 2 2 0 Spectrin repeat bZIP_2 PF07716.15 KEG11037.1 - 2.3 8.3 4.3 3.2 7.9 0.2 2.6 3 1 1 4 4 4 0 Basic region leucine zipper E2F_CC-MB PF16421.5 KEG11038.1 - 0.085 13.2 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain Dpy-30 PF05186.13 KEG11039.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 1 0 1 1 1 0 Dpy-30 motif DUF5582 PF17819.1 KEG11039.1 - 0.019 15.4 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) RIIa PF02197.17 KEG11039.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit IQ PF00612.27 KEG11041.1 - 0.0057 16.3 0.9 0.0057 16.3 0.9 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif YqaJ PF09588.10 KEG11041.1 - 0.058 13.5 0.6 0.084 13.0 0.6 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain CENP-K PF11802.8 KEG11042.1 - 0.27 10.8 9.3 0.1 12.1 6.1 1.9 2 0 0 2 2 2 0 Centromere-associated protein K FolB PF02152.18 KEG11042.1 - 0.45 11.1 3.3 3.9 8.1 2.4 2.5 1 1 1 2 2 2 0 Dihydroneopterin aldolase zf-RING_9 PF13901.6 KEG11044.1 - 3.6e-30 105.5 26.4 1.6e-23 83.8 0.6 4.9 4 1 1 5 5 5 4 Putative zinc-RING and/or ribbon FYVE PF01363.21 KEG11046.1 - 1.6e-08 34.5 9.7 2.8e-08 33.8 9.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger ATG16 PF08614.11 KEG11046.1 - 0.00011 22.6 56.6 0.0014 18.9 9.1 3.8 1 1 2 3 3 2 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KEG11046.1 - 0.00021 21.8 40.0 0.021 15.3 10.2 3.6 2 2 1 3 3 3 2 Fez1 GAS PF13851.6 KEG11046.1 - 0.00054 19.4 36.1 0.0019 17.6 9.8 3.5 1 1 2 3 3 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KEG11046.1 - 0.0013 18.8 43.3 0.046 13.7 1.7 4.8 1 1 3 4 4 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 KEG11046.1 - 0.0018 19.0 16.4 0.0033 18.1 8.7 4.4 1 1 2 4 4 3 2 Domain of unknown function (DUF4472) PEARLI-4 PF05278.12 KEG11046.1 - 0.0025 17.5 16.4 0.0054 16.4 2.0 3.2 2 1 1 3 3 3 2 Arabidopsis phospholipase-like protein (PEARLI 4) Seryl_tRNA_N PF02403.22 KEG11046.1 - 0.0054 16.9 30.9 0.073 13.3 5.7 4.4 1 1 4 6 6 6 4 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KEG11046.1 - 0.013 15.6 14.2 0.028 14.5 0.6 4.3 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KEG11046.1 - 0.014 15.4 2.5 0.014 15.4 2.5 3.8 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 KEG11046.1 - 0.03 14.8 55.5 0.24 11.9 6.9 4.4 1 1 3 4 4 4 0 Apg6 coiled-coil region REF PF05755.12 KEG11046.1 - 0.046 13.5 0.5 0.09 12.6 0.4 1.5 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) MAD PF05557.13 KEG11046.1 - 0.053 11.9 34.9 0.13 10.6 2.2 2.5 1 1 0 2 2 2 0 Mitotic checkpoint protein YabA PF06156.13 KEG11046.1 - 0.13 13.0 26.3 0.51 11.0 1.8 5.0 1 1 2 4 4 4 0 Initiation control protein YabA AcetDehyd-dimer PF09290.11 KEG11046.1 - 0.17 12.1 1.1 4.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Siva PF05458.12 KEG11046.1 - 0.17 11.5 8.9 0.041 13.6 4.7 1.9 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Jnk-SapK_ap_N PF09744.9 KEG11046.1 - 0.22 11.7 44.2 0.031 14.5 14.3 3.9 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KEG11046.1 - 0.31 9.9 39.5 0.087 11.7 3.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Atg14 PF10186.9 KEG11046.1 - 0.32 10.0 41.7 0.023 13.8 12.2 3.5 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 KEG11046.1 - 0.38 10.2 43.3 0.21 11.0 18.8 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Translat_reg PF01818.17 KEG11046.1 - 0.73 9.8 5.6 7.7 6.5 0.0 4.3 2 1 4 6 6 6 0 Bacteriophage translational regulator ZapB PF06005.12 KEG11046.1 - 0.82 10.2 44.9 0.073 13.5 1.9 5.9 2 1 3 5 5 5 0 Cell division protein ZapB IBR PF01485.21 KEG11046.1 - 1.1 9.6 12.5 0.42 10.9 8.9 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF4407 PF14362.6 KEG11046.1 - 1.3 8.3 41.1 0.015 14.6 10.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Takusan PF04822.13 KEG11046.1 - 1.9 8.4 34.6 5.5 7.0 0.7 7.7 2 2 5 8 8 8 0 Takusan Spectrin PF00435.21 KEG11046.1 - 2.2 8.8 31.7 2.1 8.9 6.3 4.7 3 2 1 4 4 4 0 Spectrin repeat FapA PF03961.13 KEG11046.1 - 4.2 5.9 29.4 0.43 9.1 0.8 4.0 1 1 3 4 4 4 0 Flagellar Assembly Protein A GIT_CC PF16559.5 KEG11046.1 - 4.2 7.3 12.3 7.9 6.4 2.9 4.9 2 2 4 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor Tweety PF04906.13 KEG11046.1 - 4.4 5.9 8.2 4.2 5.9 0.5 2.5 3 0 0 3 3 3 0 Tweety bZIP_1 PF00170.21 KEG11046.1 - 6.1 7.0 26.5 3.4 7.8 2.9 6.0 2 1 5 7 7 7 0 bZIP transcription factor COG5 PF10392.9 KEG11046.1 - 6.2 7.0 16.5 0.25 11.5 5.2 3.5 2 1 1 4 4 4 0 Golgi transport complex subunit 5 Occludin_ELL PF07303.13 KEG11046.1 - 7.2 7.4 9.9 32 5.3 0.4 4.0 2 1 2 4 4 4 0 Occludin homology domain TPR_MLP1_2 PF07926.12 KEG11046.1 - 7.9 6.6 52.2 0.87 9.7 18.7 4.7 2 1 1 4 4 3 0 TPR/MLP1/MLP2-like protein Ribosomal_L38e PF01781.18 KEG11048.1 - 5.7e-29 100.0 5.9 6.8e-29 99.8 5.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family AMP-binding PF00501.28 KEG11050.1 - 4.6e-87 292.3 0.0 5.8e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 KEG11052.1 - 5e-57 193.3 0.0 6.4e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11052.1 - 6.5e-30 104.3 0.0 9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEG11052.1 - 1.2e-05 24.4 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KEG11052.1 - 3.4e-05 23.5 0.2 7.3e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KEG11052.1 - 9.1e-05 22.5 0.1 0.16 11.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEG11052.1 - 0.00094 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG11052.1 - 0.0047 15.7 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEG11052.1 - 0.021 14.4 0.1 0.27 10.8 0.1 2.4 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SUIM_assoc PF16619.5 KEG11053.1 - 0.0022 18.0 13.4 0.011 15.8 2.1 4.2 3 1 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 FTZ PF03867.14 KEG11053.1 - 0.047 13.2 3.7 0.11 12.0 3.7 1.6 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region DSPc PF00782.20 KEG11055.1 - 6.7e-29 100.4 0.0 1.4e-28 99.3 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 KEG11055.1 - 2.4e-13 49.6 3.5 2.8e-07 30.2 3.9 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KEG11055.1 - 2.2e-06 27.9 5.5 0.13 12.8 0.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 KEG11055.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KEG11055.1 - 0.038 14.3 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain LRR_5 PF13306.6 KEG11055.1 - 0.044 13.7 0.0 0.41 10.6 0.0 1.9 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) APS_kinase PF01583.20 KEG11055.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase LRR_1 PF00560.33 KEG11055.1 - 1.7 9.5 4.0 40 5.3 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat MFS_1 PF07690.16 KEG11059.1 - 1.7e-22 79.8 45.5 5.5e-21 74.9 42.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily SieB PF14163.6 KEG11059.1 - 0.044 13.3 0.5 0.31 10.5 0.0 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B Csm1_N PF18504.1 KEG11060.1 - 0.061 13.7 1.1 0.088 13.2 0.4 1.5 2 0 0 2 2 2 0 Csm1 N-terminal domain Fumble PF03630.14 KEG11061.1 - 4.1e-92 308.9 0.0 6.1e-92 308.3 0.0 1.3 1 0 0 1 1 1 1 Fumble AMP-binding PF00501.28 KEG11061.1 - 8.7e-21 74.0 0.1 1.3e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Exo_endo_phos PF03372.23 KEG11061.1 - 1.1e-07 31.6 0.0 3.5e-07 30.0 0.0 1.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PMP22_Claudin PF00822.20 KEG11062.1 - 0.0027 17.6 1.8 0.0066 16.3 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family ABC2_membrane PF01061.24 KEG11062.1 - 0.011 15.1 4.9 0.041 13.3 4.2 1.9 1 1 1 2 2 2 0 ABC-2 type transporter DUF1345 PF07077.11 KEG11062.1 - 0.16 11.6 5.4 0.23 11.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4064 PF13273.6 KEG11062.1 - 0.47 10.8 6.0 23 5.3 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) PBP_N PF17093.5 KEG11062.1 - 0.62 10.3 0.0 0.62 10.3 0.0 2.4 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus DUF2157 PF09925.9 KEG11062.1 - 0.71 9.7 5.2 1.8 8.3 4.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Yip1 PF04893.17 KEG11062.1 - 1.3 8.8 9.3 2.1 8.0 9.3 1.4 1 1 0 1 1 1 0 Yip1 domain MARVEL PF01284.23 KEG11062.1 - 1.8 8.6 9.1 0.6 10.1 4.2 2.2 1 1 0 2 2 2 0 Membrane-associating domain DUF4307 PF14155.6 KEG11062.1 - 3.6 7.4 7.4 6.7 6.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) RNA_POL_M_15KD PF02150.16 KEG11063.1 - 4.6e-05 23.2 2.5 4.6e-05 23.2 2.5 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KEG11063.1 - 0.0035 17.1 3.8 0.0035 17.1 3.8 3.2 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) zinc_ribbon_12 PF11331.8 KEG11063.1 - 0.0038 17.0 1.6 0.0062 16.3 0.1 2.0 2 0 0 2 2 2 1 Probable zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KEG11063.1 - 0.0093 16.0 1.3 0.0093 16.0 1.3 2.5 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger RecR PF02132.15 KEG11063.1 - 0.029 13.9 1.6 1.3 8.7 0.4 2.7 2 0 0 2 2 2 0 RecR protein HypA PF01155.19 KEG11063.1 - 0.4 10.7 5.0 2.4 8.2 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 KEG11063.1 - 2.2 8.3 11.7 0.45 10.5 0.6 3.0 2 1 1 3 3 3 0 Nudix N-terminal Proteasome PF00227.26 KEG11064.1 - 5.7e-33 114.0 0.0 6.5e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TAA-Trp-ring PF15401.6 KEG11065.1 - 0.16 12.4 0.2 0.95 10.0 0.1 1.9 1 1 1 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Sec10 PF07393.11 KEG11068.1 - 3.6e-25 88.5 0.2 4.6e-23 81.6 0.0 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec10 SUIM_assoc PF16619.5 KEG11069.1 - 0.12 12.5 11.8 0.093 12.8 7.9 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 BING4CT PF08149.11 KEG11070.1 - 3.5e-29 100.4 0.0 2e-28 98.0 0.0 2.3 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.32 KEG11070.1 - 1e-06 29.3 1.0 6.5e-05 23.6 0.1 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat TFIIA PF03153.13 KEG11071.1 - 0.14 12.1 5.5 0.21 11.6 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KEG11071.1 - 2.6 7.6 9.1 3.9 7.0 9.1 1.2 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 KEG11071.1 - 4.4 5.9 9.8 7 5.2 9.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Totivirus_coat PF05518.11 KEG11071.1 - 6.5 4.7 8.9 11 3.9 8.9 1.3 1 0 0 1 1 1 0 Totivirus coat protein Meth_synt_2 PF01717.18 KEG11073.1 - 6.2e-160 531.8 0.0 2.7e-152 506.7 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEG11073.1 - 2.8e-122 408.1 0.0 1.1e-112 376.7 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain GreA_GreB_N PF03449.15 KEG11076.1 - 0.00065 19.8 1.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 2 Transcription elongation factor, N-terminal DUF3646 PF12362.8 KEG11076.1 - 0.021 15.1 0.6 0.045 14.1 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal PseudoU_synth_2 PF00849.22 KEG11078.1 - 1.1e-17 64.6 0.0 7.6e-16 58.6 0.0 2.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase zf-C3HC4_3 PF13920.6 KEG11079.1 - 1.3e-06 28.2 0.2 2.6e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG11079.1 - 1.9e-05 24.9 0.1 4.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEG11079.1 - 3.7e-05 23.5 0.1 8e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG11079.1 - 7.7e-05 22.5 0.2 0.00017 21.4 0.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEG11079.1 - 0.00015 21.7 1.7 0.00016 21.6 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG11079.1 - 0.00032 20.7 0.3 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEG11079.1 - 0.0052 16.6 0.4 0.011 15.6 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEG11079.1 - 0.015 15.1 0.4 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KEG11079.1 - 0.024 14.9 0.4 0.053 13.8 0.1 1.8 2 0 0 2 2 1 0 RING-H2 zinc finger domain Spc7 PF08317.11 KEG11079.1 - 0.03 13.2 4.5 0.041 12.8 4.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-ANAPC11 PF12861.7 KEG11079.1 - 0.032 14.3 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KEG11079.1 - 0.046 13.3 0.1 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KEG11079.1 - 0.078 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FUSC PF04632.12 KEG11079.1 - 3.5 6.0 5.8 4.6 5.6 5.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4200 PF13863.6 KEG11079.1 - 9.1 6.7 10.9 1.1 9.7 5.8 2.0 2 1 0 2 2 1 0 Domain of unknown function (DUF4200) FAM176 PF14851.6 KEG11080.1 - 0.041 13.5 18.8 2.7 7.6 9.5 3.7 4 0 0 4 4 4 0 FAM176 family DUF2052 PF09747.9 KEG11080.1 - 0.069 13.3 20.7 0.36 10.9 9.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 KEG11080.1 - 0.28 11.3 6.8 3 8.0 1.4 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Med17 PF10156.9 KEG11080.1 - 1.2 7.7 12.4 1.1 7.9 4.8 2.2 2 0 0 2 2 2 0 Subunit 17 of Mediator complex RNase_H2_suC PF08615.11 KEG11080.1 - 3.7 7.7 6.8 88 3.3 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF719 PF05334.13 KEG11080.1 - 4.4 7.5 8.4 12 6.1 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Radial_spoke PF04712.12 KEG11080.1 - 8.8 5.1 26.2 0.39 9.6 11.3 2.8 3 0 0 3 3 3 0 Radial spokehead-like protein KaiB PF07689.12 KEG11081.1 - 0.1 12.3 0.5 0.82 9.4 0.6 2.4 2 0 0 2 2 2 0 KaiB domain SUIM_assoc PF16619.5 KEG11081.1 - 0.21 11.7 4.9 0.22 11.6 0.0 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DnaJ PF00226.31 KEG11082.1 - 1.3e-21 76.4 0.2 2.3e-21 75.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 KEG11082.1 - 4.3e-05 23.0 0.0 8.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing Pex19 PF04614.12 KEG11082.1 - 0.048 13.4 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Pex19 protein family LRR_8 PF13855.6 KEG11083.1 - 2.9e-07 30.2 0.0 0.014 15.2 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KEG11083.1 - 1.5e-06 28.5 0.0 0.00022 21.5 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) DUF2052 PF09747.9 KEG11083.1 - 0.57 10.3 15.3 1.9 8.6 10.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.11 KEG11083.1 - 2.3 6.2 10.2 0.047 11.8 3.5 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen ANAPC4_WD40 PF12894.7 KEG11084.1 - 0.2 12.0 0.0 1.8 8.9 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-HC5HC2H_2 PF13832.6 KEG11085.1 - 3.9e-07 30.2 25.0 6.5e-06 26.3 14.7 3.0 2 1 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KEG11085.1 - 4.4e-05 23.7 11.9 4.4e-05 23.7 11.9 3.1 2 1 1 3 3 3 1 PHD-like zinc-binding domain Transmemb_17 PF09799.9 KEG11086.1 - 1.5e-16 60.9 5.1 2.3e-16 60.3 5.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein SNARE PF05739.19 KEG11087.1 - 0.14 12.2 0.6 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 SNARE domain Hypoth_Ymh PF09509.10 KEG11087.1 - 0.21 11.5 4.9 0.061 13.2 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) DUF16 PF01519.16 KEG11087.1 - 0.51 10.9 4.1 1.1 9.8 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KEG11087.1 - 0.66 10.2 5.9 3.7 7.7 3.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Myosin_head PF00063.21 KEG11089.1 - 7.6e-194 645.7 0.0 1.1e-193 645.2 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KEG11089.1 - 0.0029 18.0 3.6 0.0093 16.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEG11089.1 - 0.1 12.9 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain SWI-SNF_Ssr4 PF08549.10 KEG11089.1 - 0.56 8.8 3.4 0.88 8.1 3.4 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MOR2-PAG1_C PF14225.6 KEG11090.1 - 0.16 11.8 3.5 3.2 7.5 0.0 3.7 2 2 2 4 4 4 0 Cell morphogenesis C-terminal Ham1p_like PF01725.16 KEG11092.1 - 3.2e-55 187.0 0.0 3.6e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family MRP-S26 PF14943.6 KEG11095.1 - 0.063 13.2 5.4 0.13 12.1 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Suf PF05843.14 KEG11095.1 - 0.15 12.0 4.2 0.25 11.3 4.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pyridoxal_deC PF00282.19 KEG11096.1 - 4.8e-26 91.4 0.2 4.1e-25 88.3 0.0 2.3 3 0 0 3 3 3 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KEG11096.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V MRC1 PF09444.10 KEG11097.1 - 0.001 19.6 2.9 0.0021 18.6 2.9 1.4 1 0 0 1 1 1 1 MRC1-like domain Macoilin PF09726.9 KEG11099.1 - 0.093 11.3 10.5 0.13 10.7 10.5 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 KEG11099.1 - 2.2 8.2 11.8 3.7 7.4 11.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 KEG11099.1 - 2.9 6.6 13.7 5.2 5.7 13.7 1.4 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KEG11099.1 - 5.4 5.7 18.0 9.1 5.0 18.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DHO_dh PF01180.21 KEG11101.1 - 4.3e-27 95.1 0.0 4.9e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.17 KEG11101.1 - 0.045 13.2 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 PcrB family FMN_dh PF01070.18 KEG11101.1 - 0.092 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 KEG11102.1 - 1.7e-17 63.6 0.0 2e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF5437 PF17505.2 KEG11104.1 - 0.32 11.1 1.9 1.1 9.4 1.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5437) GAS PF13851.6 KEG11105.1 - 0.67 9.3 17.9 0.038 13.3 10.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5583 PF17821.1 KEG11105.1 - 0.94 9.4 2.8 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5583) PIN_4 PF13638.6 KEG11106.1 - 2.7e-15 56.8 0.0 5.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 PIN domain PIN_4 PF13638.6 KEG11107.1 - 2.2e-20 73.3 0.2 3e-20 72.8 0.2 1.1 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 KEG11107.1 - 0.012 15.9 0.6 1.1 9.5 0.2 2.5 1 1 1 2 2 2 0 PIN like domain DUF4699 PF15770.5 KEG11107.1 - 0.03 14.1 0.8 0.033 14.0 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Glutaredoxin PF00462.24 KEG11108.1 - 3.8e-11 43.0 0.1 5.3e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KEG11108.1 - 0.0095 16.3 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 KEG11108.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 KEG11108.1 - 0.089 12.9 0.1 0.16 12.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin domain UPF0102 PF02021.17 KEG11108.1 - 0.092 13.0 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0102 DUF1387 PF07139.11 KEG11109.1 - 5.2 6.7 20.4 8.1 6.1 20.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ARD PF03079.14 KEG11111.1 - 1.9e-36 125.6 0.0 2.6e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.11 KEG11111.1 - 8.1e-10 38.4 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.11 KEG11111.1 - 3.3e-05 23.5 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEG11111.1 - 0.0027 17.6 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Pkinase PF00069.25 KEG11112.1 - 6.1e-52 176.6 0.0 1.8e-30 106.2 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11112.1 - 1e-32 113.4 0.0 3.1e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG11112.1 - 0.00011 21.1 0.0 0.00033 19.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KEG11112.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KEG11112.1 - 0.036 13.4 0.7 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCC1 PF00415.18 KEG11113.1 - 4e-70 232.2 42.1 7.1e-13 49.0 0.5 12.6 11 2 0 11 11 11 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG11113.1 - 1.4e-44 149.0 59.1 7.2e-08 32.0 0.4 12.8 13 0 0 13 13 13 9 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.11 KEG11113.1 - 0.035 13.9 0.8 11 5.9 0.0 4.0 4 0 0 4 4 4 0 GAD-like domain DUF525 PF04379.14 KEG11114.1 - 8e-20 70.9 0.0 1.4e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 ApaG domain RCC1 PF00415.18 KEG11115.1 - 7.9e-62 205.7 32.0 1.5e-12 47.9 0.8 11.5 11 0 0 11 11 11 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG11115.1 - 1e-46 155.8 62.4 1.2e-07 31.3 0.4 12.1 12 0 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KEG11115.1 - 0.049 13.4 0.6 0.63 9.7 0.0 3.1 4 0 0 4 4 4 0 TUP1-like enhancer of split RRM_1 PF00076.22 KEG11116.1 - 3.9e-11 42.6 0.1 5.8e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KEG11116.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_1 PF00076.22 KEG11119.1 - 1e-09 38.1 0.0 5.4e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2612 PF11041.8 KEG11120.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) Mucin PF01456.17 KEG11122.1 - 0.0042 17.1 1.3 0.0042 17.1 1.3 3.7 1 1 1 3 3 3 2 Mucin-like glycoprotein GARP PF16731.5 KEG11122.1 - 0.0048 16.6 49.0 0.05 13.3 9.4 3.4 1 1 2 3 3 3 2 Glutamic acid/alanine-rich protein of Trypanosoma Raco_middle PF17651.1 KEG11122.1 - 0.036 13.8 2.3 0.081 12.6 2.3 1.6 1 0 0 1 1 1 0 RACo middle region DUF4110 PF13422.6 KEG11122.1 - 0.97 9.5 6.8 6.6 6.9 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4110) DUF4813 PF16072.5 KEG11123.1 - 0.0083 15.8 9.2 0.0083 15.8 9.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4813) RdRP_4 PF02123.16 KEG11123.1 - 0.055 12.3 1.9 0.057 12.3 1.9 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Latrophilin PF02354.16 KEG11123.1 - 0.26 10.3 4.8 0.33 10.0 4.8 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region DUF930 PF06059.12 KEG11123.1 - 2.2 8.9 6.0 2 9.1 1.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF930) Mucin PF01456.17 KEG11124.1 - 0.00048 20.1 1.3 0.00058 19.9 1.3 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein gag-asp_proteas PF13975.6 KEG11124.1 - 0.33 11.5 5.4 1.5 9.4 2.1 2.1 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Zea_mays_MuDR PF05928.11 KEG11124.1 - 4.8 6.8 10.0 5.9 6.5 10.0 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) BtpA PF03437.15 KEG11125.1 - 0.011 15.2 0.3 0.013 14.9 0.3 1.0 1 0 0 1 1 1 0 BtpA family DMPK_coil PF08826.10 KEG11125.1 - 0.046 13.8 2.7 0.066 13.3 2.7 1.2 1 0 0 1 1 1 0 DMPK coiled coil domain like FIT1_2 PF17357.2 KEG11125.1 - 1.6 8.9 9.7 0.12 12.5 2.3 2.0 1 1 0 2 2 2 0 Facilitor Of iron transport 1 and 2 Tetraspanin PF00335.20 KEG11128.1 - 2.4e-22 79.8 2.2 3.3e-22 79.3 2.2 1.2 1 0 0 1 1 1 1 Tetraspanin family PRRSV_Env PF02340.15 KEG11129.1 - 0.25 10.7 1.8 0.34 10.3 1.0 1.6 1 1 1 2 2 2 0 PRRSV putative envelope protein PRK PF00485.18 KEG11131.1 - 3e-06 27.1 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KEG11131.1 - 0.00017 22.2 0.0 0.011 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEG11131.1 - 0.019 15.1 0.0 0.12 12.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KEG11131.1 - 0.039 14.2 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KEG11131.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TP6A_N PF04406.14 KEG11133.1 - 1.5e-13 50.5 0.1 3e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RRM_1 PF00076.22 KEG11134.1 - 4.8e-14 51.9 0.0 9.2e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 KEG11134.1 - 3e-10 40.6 0.0 2.4e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.6 KEG11134.1 - 0.032 13.8 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-rbx1 PF12678.7 KEG11135.1 - 2.7e-16 59.6 15.3 3.1e-16 59.4 14.2 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEG11135.1 - 3.5e-11 43.0 8.8 4.1e-11 42.8 8.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KEG11135.1 - 0.00012 22.3 20.6 0.002 18.4 20.7 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG11135.1 - 0.0068 16.2 11.8 0.0068 16.2 11.8 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG11135.1 - 0.17 11.8 18.3 2.2 8.2 18.3 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG11135.1 - 0.21 11.7 10.6 0.19 11.8 8.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Tymo_45kd_70kd PF03251.13 KEG11135.1 - 0.28 10.1 0.0 0.37 9.7 0.0 1.1 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein Zn_ribbon_17 PF17120.5 KEG11135.1 - 0.53 9.9 19.8 16 5.2 18.8 2.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KEG11135.1 - 1.4 9.0 17.1 7.4 6.6 16.3 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 KEG11136.1 - 8.3e-18 64.4 12.3 2.8e-14 53.1 4.5 2.4 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEG11136.1 - 2.6e-13 49.8 12.9 4.5e-09 36.2 2.6 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KEG11136.1 - 1e-07 32.2 5.4 1e-07 32.2 5.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG11136.1 - 5e-05 23.1 6.6 5e-05 23.1 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG11136.1 - 0.0015 18.4 9.8 0.0056 16.5 3.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG11136.1 - 0.0045 16.9 3.5 0.0045 16.9 3.5 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KEG11136.1 - 0.0052 16.6 4.4 0.0052 16.6 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEG11136.1 - 0.011 15.5 4.2 0.011 15.5 4.2 3.0 3 0 0 3 3 3 0 RING-like zinc finger Prok-RING_4 PF14447.6 KEG11136.1 - 0.014 15.2 4.4 0.014 15.2 4.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DiS_P_DiS PF06750.13 KEG11136.1 - 0.081 13.1 4.8 1.9 8.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-RING_9 PF13901.6 KEG11136.1 - 0.095 12.7 5.4 0.49 10.3 0.9 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Zn_ribbon_17 PF17120.5 KEG11136.1 - 0.11 12.1 14.8 0.073 12.7 7.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KEG11136.1 - 0.36 11.0 10.2 3.7 7.7 0.2 2.8 2 1 0 2 2 2 0 KIAA1045 RING finger zf-RING_UBOX PF13445.6 KEG11136.1 - 2.1 8.4 13.7 0.12 12.4 5.2 2.9 2 1 1 3 3 3 0 RING-type zinc-finger Mito_carr PF00153.27 KEG11137.1 - 6.4e-48 160.6 3.5 6e-19 67.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kinesin PF00225.23 KEG11138.1 - 3.5e-87 292.4 0.1 5.2e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG11138.1 - 3.1e-18 66.1 0.2 9.5e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding DEAD PF00270.29 KEG11138.1 - 0.12 12.1 0.3 7.1 6.4 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF5443 PF17518.2 KEG11138.1 - 0.17 10.8 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5443) Bac_DnaA PF00308.18 KEG11138.1 - 0.35 10.7 2.3 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein Peptidase_C97 PF05903.14 KEG11140.1 - 5.7e-27 94.4 0.1 1.2e-26 93.4 0.1 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KEG11140.1 - 0.0023 18.3 0.0 0.0075 16.6 0.0 1.8 1 0 0 1 1 1 1 Lecithin retinol acyltransferase LEF-8 PF04941.12 KEG11141.1 - 0.046 12.0 0.0 0.068 11.4 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) Pkinase PF00069.25 KEG11142.1 - 4.3e-46 157.4 0.0 4.1e-40 137.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11142.1 - 2e-17 63.3 0.0 8.1e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KEG11142.1 - 4.1e-05 23.0 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG11142.1 - 0.00019 20.3 1.0 0.0002 20.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KEG11142.1 - 0.00034 20.0 0.0 0.0051 16.2 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Nop14 PF04147.12 KEG11142.1 - 0.0061 14.9 2.8 0.0083 14.4 2.8 1.1 1 0 0 1 1 1 1 Nop14-like family APH PF01636.23 KEG11142.1 - 0.032 14.2 0.0 6.1 6.7 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family NOA36 PF06524.12 KEG11142.1 - 0.2 11.0 4.5 0.35 10.2 4.5 1.3 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 KEG11142.1 - 0.5 10.2 8.6 6.8 6.5 0.2 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Paf1 PF03985.13 KEG11142.1 - 9.3 5.1 10.4 14 4.5 10.4 1.1 1 0 0 1 1 1 0 Paf1 Sugar_tr PF00083.24 KEG11143.1 - 1.1e-115 387.1 27.0 1.3e-115 386.9 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEG11143.1 - 1.5e-33 116.2 31.3 1.5e-33 116.2 31.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TM140 PF14985.6 KEG11143.1 - 0.058 12.9 0.2 0.058 12.9 0.2 2.4 2 0 0 2 2 2 0 TM140 protein family Kelch_5 PF13854.6 KEG11144.1 - 5.1e-19 67.8 3.0 1.2e-05 25.1 0.0 4.7 4 1 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 KEG11144.1 - 5.3e-17 61.6 10.6 2.3e-06 27.5 0.1 4.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KEG11144.1 - 3.3e-13 49.6 17.6 0.0028 17.9 0.1 6.1 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KEG11144.1 - 8.5e-09 35.1 3.4 0.04 13.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KEG11144.1 - 1.7e-08 33.9 7.1 0.011 15.4 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KEG11144.1 - 3.9e-08 33.3 0.2 0.053 13.8 0.0 4.3 4 0 0 4 4 4 3 Kelch motif L_biotic_typeA PF04604.13 KEG11145.1 - 0.054 13.4 0.7 0.12 12.3 0.2 1.8 2 0 0 2 2 2 0 Type-A lantibiotic DUF1935 PF09149.10 KEG11146.1 - 6.2e-34 116.5 0.0 1.2e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.16 KEG11146.1 - 4.5e-30 103.8 2.8 1.5e-10 41.0 0.0 3.2 3 0 0 3 3 3 3 META domain Pyr_redox_2 PF07992.14 KEG11146.1 - 0.021 14.0 0.1 0.14 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Asp23 PF03780.13 KEG11146.1 - 0.032 14.7 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Asp23 family, cell envelope-related function META PF03724.16 KEG11147.1 - 8.6e-14 51.4 0.0 1.1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 META domain LRR_6 PF13516.6 KEG11148.1 - 6e-18 63.3 11.4 3.2e-06 26.8 0.1 6.8 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KEG11148.1 - 9.6e-10 38.6 14.3 0.00074 19.9 0.2 5.2 4 2 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11148.1 - 0.00013 21.7 18.5 0.11 12.2 1.3 5.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KEG11148.1 - 0.00029 21.0 8.9 12 6.9 0.1 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat Acyltransferase PF01553.21 KEG11149.1 - 1.3e-15 57.2 0.0 2.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KEG11149.1 - 4.2e-07 30.0 0.1 1.8e-05 24.7 0.2 2.9 2 1 0 2 2 2 1 Acyltransferase C-terminus Sec63 PF02889.16 KEG11150.1 - 7.5e-67 225.2 0.0 5.6e-64 215.8 0.0 2.8 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KEG11150.1 - 1e-30 106.8 0.1 2.7e-25 89.1 0.2 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KEG11150.1 - 3.8e-10 40.0 0.0 1.4e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEG11150.1 - 7.5e-08 32.7 0.0 4.6e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 KEG11150.1 - 8.5e-05 22.7 0.1 0.00019 21.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_22 PF13401.6 KEG11150.1 - 0.0042 17.4 0.3 0.15 12.3 0.1 3.5 3 2 0 3 3 3 1 AAA domain FH2 PF02181.23 KEG11152.1 - 4.1e-47 161.1 0.0 5.8e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF1712 PF08217.11 KEG11153.1 - 1.1e-06 27.5 0.0 1.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Telomerase_RBD PF12009.8 KEG11154.1 - 1.5e-20 73.6 1.7 4e-20 72.3 1.7 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain Apolipoprotein PF01442.18 KEG11155.1 - 0.0019 18.1 14.3 0.0038 17.1 13.8 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain TolA_bind_tri PF16331.5 KEG11155.1 - 0.0062 16.6 6.1 0.0062 16.6 6.1 3.5 3 1 1 4 4 4 1 TolA binding protein trimerisation Macoilin PF09726.9 KEG11155.1 - 0.0089 14.6 25.1 0.025 13.2 25.1 1.7 1 1 0 1 1 1 1 Macoilin family COG2 PF06148.11 KEG11155.1 - 0.027 14.5 5.6 1.6 8.8 3.1 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 KEG11155.1 - 0.1 11.2 6.4 0.43 9.2 6.4 2.0 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.11 KEG11155.1 - 0.34 9.7 13.3 0.91 8.3 9.0 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KEG11155.1 - 0.46 11.0 12.5 0.19 12.3 8.9 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region LMBR1 PF04791.16 KEG11155.1 - 0.8 8.5 5.7 1.7 7.4 5.6 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1640 PF07798.11 KEG11155.1 - 0.85 9.6 12.6 0.72 9.9 7.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF5082 PF16888.5 KEG11155.1 - 0.98 9.7 7.5 3.1 8.1 0.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 KEG11155.1 - 1.4 9.6 18.2 8.2 7.1 6.7 3.8 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MerR-DNA-bind PF09278.11 KEG11155.1 - 2.5 8.7 7.5 3.9 8.1 2.3 3.0 2 1 0 2 2 2 0 MerR, DNA binding DUF4404 PF14357.6 KEG11155.1 - 4.2 8.1 8.3 2 9.1 4.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) OmpH PF03938.14 KEG11155.1 - 4.3 7.7 13.9 22 5.4 0.0 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KEG11155.1 - 5.9 7.0 14.4 0.53 10.4 7.1 2.6 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 KEG11155.1 - 7.3 6.7 12.9 2.4e+02 1.7 12.6 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus THOC7 PF05615.13 KEG11155.1 - 8.7 6.6 13.2 8.7 6.6 7.2 2.8 1 1 1 2 2 2 0 Tho complex subunit 7 Glyco_transf_4 PF13439.6 KEG11157.1 - 3.4e-16 59.7 0.6 2.3e-15 57.0 0.2 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEG11157.1 - 2.7e-15 57.0 0.0 5.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEG11157.1 - 1.5e-11 45.0 0.2 6.9e-11 42.8 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KEG11157.1 - 1.3e-10 41.0 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEG11157.1 - 0.0002 21.7 0.1 0.00047 20.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KEG11157.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain TPPK_C PF12555.8 KEG11159.1 - 0.00027 20.9 0.3 0.00038 20.4 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal SdpI PF13630.6 KEG11159.1 - 0.023 14.8 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family PBP_N PF17093.5 KEG11159.1 - 0.077 13.2 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF2951 PF11166.8 KEG11159.1 - 0.083 13.1 0.1 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) CDC73_C PF05179.14 KEG11160.1 - 1.1e-31 109.6 0.0 1.7e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF3710 PF12502.8 KEG11160.1 - 0.15 11.7 0.1 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3710) Tr-sialidase_C PF11052.8 KEG11161.1 - 0.45 10.7 2.8 1.1 9.5 2.8 1.7 1 0 0 1 1 1 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal Kinesin PF00225.23 KEG11166.1 - 2.7e-80 269.8 0.0 3.4e-48 164.3 0.0 2.5 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KEG11166.1 - 8.3e-15 55.0 0.0 6.3e-14 52.2 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding LRR_6 PF13516.6 KEG11167.1 - 0.0096 15.9 4.3 1.4 9.1 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.33 KEG11167.1 - 0.025 15.1 1.5 15 6.6 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 KEG11167.1 - 0.18 12.3 4.8 0.91 10.0 4.8 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11167.1 - 1.2 8.9 5.6 15 5.5 5.0 2.4 1 1 1 2 2 2 0 Leucine rich repeat Guanylate_cyc PF00211.20 KEG11168.1 - 1.3e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 KEG11169.1 - 1.2e-32 113.1 0.0 1.9e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 KEG11169.1 - 8.8e-08 32.2 1.3 1.9e-07 31.1 1.3 1.5 1 0 0 1 1 1 1 Periplasmic binding protein AJAP1_PANP_C PF15298.6 KEG11169.1 - 0.056 13.6 0.8 0.095 12.9 0.1 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus SseC PF04888.12 KEG11169.1 - 0.15 11.7 1.0 0.57 9.7 0.1 1.9 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PrgI PF12666.7 KEG11169.1 - 0.37 11.5 1.3 1.3 9.8 1.3 1.9 1 0 0 1 1 1 0 PrgI family protein LRR_4 PF12799.7 KEG11170.1 - 4.8e-16 58.6 23.9 0.00027 21.3 0.2 10.6 6 3 6 13 13 13 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11170.1 - 4.5e-06 26.3 16.0 0.07 12.9 0.1 7.2 8 1 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.6 KEG11170.1 - 0.0012 18.8 29.5 0.52 10.5 1.3 11.5 13 1 1 14 14 14 2 Leucine Rich repeat LRR_1 PF00560.33 KEG11170.1 - 1.1 10.1 22.7 12 6.9 1.3 8.7 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_2 PF07723.13 KEG11170.1 - 5.3 7.9 19.1 0.93 10.3 0.2 7.5 9 0 0 9 9 9 0 Leucine Rich Repeat SHIPPO-rpt PF07004.12 KEG11172.1 - 1.1e-67 222.0 205.7 0.0026 18.6 0.1 41.8 42 0 0 42 42 42 37 Sperm-tail PG-rich repeat ABC-3 PF00950.17 KEG11173.1 - 0.034 13.6 0.0 0.034 13.6 0.0 1.6 2 0 0 2 2 2 0 ABC 3 transport family DUF4139 PF13598.6 KEG11174.1 - 6.6e-40 137.1 0.3 7.5e-40 136.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF3437 PF11919.8 KEG11175.1 - 2.6e-21 75.3 0.0 9e-21 73.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 KEG11175.1 - 1.7e-09 36.9 0.0 1.4e-05 24.0 0.1 2.9 1 1 1 2 2 2 2 Proteasome-substrate-size regulator, mid region MMR_HSR1 PF01926.23 KEG11176.1 - 0.034 14.2 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KEG11176.1 - 0.036 13.5 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 KEG11176.1 - 0.064 12.6 0.1 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family Herpes_UL7 PF01677.16 KEG11176.1 - 0.12 12.0 0.0 11 5.6 0.0 2.1 1 1 1 2 2 2 0 Herpesvirus UL7 like FB_lectin PF07367.11 KEG11177.1 - 0.15 12.0 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 Fungal fruit body lectin NPL PF17800.1 KEG11180.1 - 4.5e-17 62.5 0.1 4.5e-17 62.5 0.1 2.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nop14 PF04147.12 KEG11180.1 - 0.39 8.9 51.0 0.51 8.5 51.0 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KEG11180.1 - 4.9 5.8 5.4 6.6 5.4 5.4 1.2 1 0 0 1 1 1 0 Presenilin 2-oxoacid_dh PF00198.23 KEG11181.1 - 4.1e-80 268.6 0.0 5.2e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEG11181.1 - 2.1e-20 72.3 1.6 3.4e-20 71.6 1.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEG11181.1 - 6.6e-08 32.3 0.7 0.0051 16.6 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 KEG11181.1 - 0.00082 19.3 0.2 0.0016 18.4 0.2 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 KEG11181.1 - 0.0059 17.3 0.9 0.05 14.3 0.2 2.3 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 KEG11181.1 - 0.016 14.5 0.3 0.11 11.7 0.1 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Rft-1 PF04506.13 KEG11182.1 - 8.5e-57 193.0 8.1 4.8e-46 157.6 2.1 2.0 2 0 0 2 2 2 2 Rft protein GCD14 PF08704.10 KEG11183.1 - 9.3e-68 228.6 0.2 7.7e-42 143.7 0.0 3.0 2 1 1 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KEG11183.1 - 3.4e-09 36.7 0.0 6.7e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG11183.1 - 3e-05 24.7 0.1 0.0002 22.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain GCD14_N PF14801.6 KEG11183.1 - 3.3e-05 23.6 0.1 7e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 KEG11183.1 - 0.00011 22.0 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KEG11183.1 - 0.0018 18.9 0.1 0.023 15.3 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG11183.1 - 0.0027 18.4 0.0 0.063 14.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 KEG11183.1 - 0.0047 16.1 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Fibrillarin Methyltransf_24 PF13578.6 KEG11183.1 - 0.07 14.2 0.0 0.17 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEG11183.1 - 0.095 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KEG11183.1 - 0.1 11.9 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family WW PF00397.26 KEG11184.1 - 5.3e-07 29.6 1.6 1.5e-06 28.2 1.6 1.8 1 0 0 1 1 1 1 WW domain MCM PF00493.23 KEG11185.1 - 3.3e-92 307.6 0.7 6.2e-92 306.7 0.7 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEG11185.1 - 9.1e-35 119.3 0.4 1.8e-34 118.3 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEG11185.1 - 6e-20 71.5 5.8 8.1e-20 71.0 3.7 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 KEG11185.1 - 2.5e-10 40.5 0.1 2.5e-10 40.5 0.1 2.2 2 0 0 2 2 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 KEG11185.1 - 1.1e-07 31.4 0.0 4.6e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KEG11185.1 - 3.7e-06 27.5 0.0 1.6e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KEG11185.1 - 0.0071 16.3 0.1 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEG11185.1 - 0.0096 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEG11185.1 - 0.019 14.6 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4834 PF16118.5 KEG11185.1 - 0.65 11.0 2.6 3.8 8.5 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 KEG11185.1 - 0.89 9.1 10.9 0.16 11.6 6.5 1.8 2 0 0 2 2 2 0 Spt20 family Beach PF02138.18 KEG11190.1 - 3.3e-103 344.8 0.0 1.1e-102 343.2 0.0 1.9 2 0 0 2 2 2 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KEG11190.1 - 0.0055 16.9 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily AAA_assoc_2 PF16193.5 KEG11190.1 - 0.035 14.5 0.1 4.5 7.7 0.0 3.0 3 0 0 3 3 3 0 AAA C-terminal domain NTP_transferase PF00483.23 KEG11191.1 - 1.1e-48 166.0 0.0 1.3e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEG11191.1 - 1.9e-13 51.1 0.0 2.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KEG11191.1 - 3.9e-13 48.6 9.6 1.6e-09 37.1 2.3 3.2 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.19 KEG11191.1 - 3.3e-05 23.9 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Fucokinase PF07959.12 KEG11191.1 - 5.2e-05 22.4 0.0 9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep_loop PF18776.1 KEG11191.1 - 0.089 12.4 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Hexapeptide repeat including loop Hexapep_2 PF14602.6 KEG11191.1 - 0.35 10.7 12.3 0.42 10.4 8.2 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Methyltransf_16 PF10294.9 KEG11192.1 - 4.8e-15 55.7 0.0 6.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KEG11192.1 - 0.00093 19.9 0.0 0.0024 18.6 0.1 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG11192.1 - 0.029 15.1 0.0 0.051 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEG11192.1 - 0.058 12.9 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MethyltransfD12 PF02086.15 KEG11192.1 - 0.059 13.0 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PCMT PF01135.19 KEG11192.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KEG11192.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEG11192.1 - 0.085 12.6 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain RMI1_N PF08585.12 KEG11193.1 - 1.1e-19 71.1 0.0 1.5e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein Tropomyosin_1 PF12718.7 KEG11194.1 - 7.7e-05 22.9 9.9 7.7e-05 22.9 9.9 4.8 1 1 4 5 5 5 1 Tropomyosin like Alkyl_sulf_C PF14864.6 KEG11194.1 - 5.3 7.3 6.7 0.89 9.8 0.1 2.8 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal DUF4407 PF14362.6 KEG11194.1 - 5.4 6.3 36.9 0.22 10.8 4.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Arginase PF00491.21 KEG11195.1 - 5.9e-27 94.9 0.0 1.1e-26 94.0 0.0 1.4 1 1 0 1 1 1 1 Arginase family Bys1 PF04681.12 KEG11196.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein Pro_isomerase PF00160.21 KEG11197.1 - 9e-46 156.0 0.0 1.4e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0561 PF10573.9 KEG11197.1 - 0.27 11.4 3.1 0.55 10.4 3.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 AhpC-TSA PF00578.21 KEG11198.1 - 5.7e-37 126.4 0.0 7.6e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEG11198.1 - 5.6e-15 55.3 0.0 7.4e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KEG11198.1 - 8.5e-11 41.5 0.4 1.7e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin OKR_DC_1_C PF03711.15 KEG11198.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain UTP15_C PF09384.10 KEG11199.1 - 7.2e-27 93.9 1.0 1.4e-26 92.9 1.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KEG11199.1 - 1.7e-14 53.9 4.7 0.00016 22.4 0.2 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG11199.1 - 0.00056 20.2 0.0 4.9 7.5 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 KEG11199.1 - 0.038 12.7 0.1 0.076 11.7 0.0 1.5 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal RRM_1 PF00076.22 KEG11201.1 - 0.00093 19.0 0.0 0.05 13.4 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArgoMid PF16487.5 KEG11201.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute zf-CCHC PF00098.23 KEG11202.1 - 0.068 13.3 20.6 0.059 13.5 2.4 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 KEG11202.1 - 0.43 10.4 0.1 0.43 10.4 0.1 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 KEG11202.1 - 6.2 6.9 25.6 0.31 11.1 0.8 4.9 4 0 0 4 4 4 0 Zinc knuckle Cyt-b5 PF00173.28 KEG11203.1 - 1.3e-19 70.1 0.0 1.6e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nucleoside_tran PF01733.18 KEG11204.1 - 3.3e-30 105.5 4.4 5.8e-30 104.7 4.4 1.3 1 0 0 1 1 1 1 Nucleoside transporter Saf_2TM PF18303.1 KEG11204.1 - 0.23 11.0 1.3 0.56 9.8 1.3 1.6 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Phage_holin_1 PF04531.13 KEG11204.1 - 0.63 10.6 2.9 0.66 10.5 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage holin NdhL PF10716.9 KEG11204.1 - 1.2 9.2 9.6 0.3 11.1 1.4 2.9 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit DUF4859 PF16151.5 KEG11205.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) TruB_N PF01509.18 KEG11206.1 - 0.044 14.2 0.0 0.47 10.8 0.0 2.5 3 0 0 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) UB2H PF14814.6 KEG11208.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.6 1 1 1 2 2 2 0 Bifunctional transglycosylase second domain Flagellar_rod PF05149.12 KEG11209.1 - 1.1e-95 320.4 25.6 2.1e-95 319.5 25.6 1.5 1 0 0 1 1 1 1 Paraflagellar rod protein SH3_9 PF14604.6 KEG11209.1 - 6.7e-13 48.3 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEG11209.1 - 2.6e-11 43.0 0.0 4.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEG11209.1 - 1.2e-07 31.3 0.0 2.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FlxA PF14282.6 KEG11209.1 - 5 7.2 12.0 6.1 6.9 1.2 3.7 2 1 0 2 2 2 0 FlxA-like protein DUF4710 PF15828.5 KEG11210.1 - 0.35 11.0 4.9 0.14 12.3 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DSPc PF00782.20 KEG11211.1 - 5.5e-25 87.7 0.0 8.7e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG11211.1 - 0.004 16.8 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MMR_HSR1 PF01926.23 KEG11212.1 - 1.7e-21 76.4 0.0 2.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG11212.1 - 3.1e-08 33.3 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEG11212.1 - 0.042 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 KEG11212.1 - 0.052 12.5 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KEG11212.1 - 0.12 12.2 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEG11212.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KEG11212.1 - 0.18 12.3 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KEG11212.1 - 0.2 11.1 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit YchF-GTPase_C PF06071.13 KEG11213.1 - 9.3e-21 73.8 0.0 1.6e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) TGS PF02824.21 KEG11213.1 - 0.00095 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain SecA_PP_bind PF01043.20 KEG11213.1 - 0.047 14.3 0.1 0.062 14.0 0.1 1.5 1 1 0 1 1 1 0 SecA preprotein cross-linking domain CENP-F_leu_zip PF10473.9 KEG11214.1 - 0.00062 19.8 7.7 0.00062 19.8 7.7 5.5 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 KEG11214.1 - 0.0044 16.4 11.6 0.0044 16.4 11.6 4.8 1 1 4 5 5 5 2 Domain of unknown function (DUF4407) DUF4250 PF14056.6 KEG11214.1 - 0.0072 16.3 0.3 0.0072 16.3 0.3 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4250) NADH_Oxid_Nqo15 PF11497.8 KEG11214.1 - 0.04 13.9 0.2 7.7 6.6 0.1 2.9 3 0 0 3 3 3 0 NADH-quinone oxidoreductase chain 15 TMF_TATA_bd PF12325.8 KEG11215.1 - 0.00011 22.4 8.8 0.00011 22.4 8.8 3.8 3 1 1 4 4 4 1 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.7 KEG11215.1 - 0.0029 17.7 14.1 0.0029 17.7 14.1 3.5 2 2 0 2 2 1 1 Tropomyosin like Fmp27_WPPW PF10359.9 KEG11215.1 - 0.0062 15.4 29.4 0.011 14.6 13.1 2.4 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain SlyX PF04102.12 KEG11215.1 - 0.0096 16.5 4.8 0.0096 16.5 4.8 6.2 3 2 3 6 6 4 1 SlyX ADIP PF11559.8 KEG11215.1 - 0.0099 16.0 11.6 0.0099 16.0 11.6 4.3 2 2 2 4 4 4 1 Afadin- and alpha -actinin-Binding ERM PF00769.19 KEG11215.1 - 0.01 15.6 19.2 0.01 15.6 19.2 2.4 2 1 0 2 2 1 0 Ezrin/radixin/moesin family EspB PF05802.11 KEG11215.1 - 0.011 15.7 3.5 0.011 15.7 3.5 2.8 2 1 0 2 2 2 0 Enterobacterial EspB protein DUF641 PF04859.12 KEG11215.1 - 0.012 16.0 3.0 0.012 16.0 3.0 3.7 3 2 1 4 4 4 0 Plant protein of unknown function (DUF641) FlgN PF05130.12 KEG11215.1 - 0.015 15.8 15.7 0.015 15.8 15.7 2.8 2 1 1 3 3 3 0 FlgN protein Laminin_II PF06009.12 KEG11215.1 - 0.015 15.3 5.1 0.015 15.3 5.1 3.3 2 1 1 3 3 3 0 Laminin Domain II SHE3 PF17078.5 KEG11215.1 - 0.025 14.3 21.7 0.066 12.9 4.9 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 KEG11215.1 - 0.026 14.8 1.5 0.026 14.8 1.5 3.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KEG11215.1 - 0.026 15.0 4.6 0.026 15.0 4.6 2.9 2 1 0 3 3 2 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 KEG11215.1 - 0.029 15.0 17.8 0.029 15.0 17.8 4.3 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Spc34 PF08657.10 KEG11215.1 - 0.033 14.0 1.3 0.033 14.0 1.3 3.4 1 1 1 3 3 3 0 DASH complex subunit Spc34 CENP-F_leu_zip PF10473.9 KEG11215.1 - 0.042 13.9 40.2 0.13 12.3 8.7 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KEG11215.1 - 0.21 10.9 40.7 0.065 12.6 8.3 3.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KEG11215.1 - 0.53 9.1 43.7 0.15 10.9 20.0 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KEG11215.1 - 0.78 9.8 15.7 0.7 9.9 2.9 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 KEG11215.1 - 1.1 9.8 6.1 9 6.9 1.1 3.2 2 2 0 2 2 2 0 YtxH-like protein Sec34 PF04136.15 KEG11215.1 - 1.3 8.9 23.0 0.73 9.7 5.3 3.3 2 1 1 3 3 3 0 Sec34-like family SseC PF04888.12 KEG11215.1 - 2.6 7.6 13.9 0.094 12.3 1.8 3.0 2 1 1 3 3 3 0 Secretion system effector C (SseC) like family DUF4446 PF14584.6 KEG11215.1 - 2.9 7.9 16.7 2.1 8.3 1.7 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF4446) DUF948 PF06103.11 KEG11215.1 - 3.4 8.0 9.1 6.4 7.1 2.9 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KEG11215.1 - 3.9 7.9 44.4 1.6 9.1 18.6 2.9 1 1 1 2 2 2 0 Fez1 HMMR_N PF15905.5 KEG11215.1 - 4.3 6.7 42.0 0.18 11.2 11.9 2.9 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 KEG11215.1 - 4.4 7.8 19.6 0.61 10.5 2.1 4.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KEG11215.1 - 4.7 6.7 42.9 0.45 10.0 7.7 3.3 3 1 1 4 4 3 0 Intermediate filament protein FPP PF05911.11 KEG11215.1 - 4.7 5.3 36.2 1.2 7.2 14.2 2.7 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 KEG11215.1 - 4.9 7.2 19.6 1.1 9.3 4.1 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KEG11215.1 - 5.1 7.3 23.0 0.37 11.0 3.9 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family RmuC PF02646.16 KEG11215.1 - 5.9 5.9 22.4 2.5 7.2 8.5 2.7 2 1 0 2 2 2 0 RmuC family TMPIT PF07851.13 KEG11215.1 - 6.6 5.9 20.7 1.5 8.0 5.9 2.5 2 1 0 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 KEG11215.1 - 6.7 6.0 38.1 36 3.6 10.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Phage_int_SAM_6 PF18644.1 KEG11215.1 - 6.8 6.7 6.4 4.3 7.4 0.6 2.5 3 0 0 3 3 2 0 Phage integrase SAM-like domain NPV_P10 PF05531.12 KEG11215.1 - 7.3 7.1 10.5 8.6 6.9 2.1 3.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 KEG11215.1 - 8.9 6.6 14.3 0.4 10.9 3.7 3.0 2 1 0 2 2 2 0 Haemolysin XhlA PEPCK_ATP PF01293.20 KEG11216.1 - 6.8e-191 635.0 0.0 8.9e-191 634.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KEG11216.1 - 0.087 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 KEG11217.1 - 1.4e-44 152.5 0.0 1.8e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase NUDIX_2 PF13869.6 KEG11218.1 - 3.2e-19 69.3 0.3 3.5e-19 69.1 0.3 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Vps8 PF12816.7 KEG11219.1 - 0.013 15.1 0.3 0.02 14.4 0.2 1.5 1 1 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 RC-P840_PscD PF10657.9 KEG11219.1 - 0.041 14.0 0.0 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD DUF249 PF03158.13 KEG11219.1 - 0.063 13.0 0.3 0.94 9.1 0.1 2.0 1 1 1 2 2 2 0 Multigene family 530 protein MMR_HSR1 PF01926.23 KEG11220.1 - 2.2e-41 140.5 0.0 1.7e-19 69.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG11220.1 - 3.9e-21 75.5 0.3 1.7e-10 40.8 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KEG11220.1 - 2.2e-17 63.0 0.0 1.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 KEG11220.1 - 5.7e-15 55.8 0.1 6e-05 23.2 0.0 4.1 3 1 1 4 4 4 3 Dynamin family KH_dom-like PF14714.6 KEG11220.1 - 3.3e-14 52.9 0.3 7.2e-14 51.9 0.3 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal RsgA_GTPase PF03193.16 KEG11220.1 - 7.2e-13 48.8 0.1 0.025 14.5 0.0 4.3 2 1 2 4 4 4 3 RsgA GTPase AIG1 PF04548.16 KEG11220.1 - 3.6e-12 46.1 0.0 5.3e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 KEG11220.1 - 1.5e-10 41.3 0.0 0.00078 19.6 0.0 3.3 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEG11220.1 - 7.3e-10 38.6 0.0 8.8e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 KEG11220.1 - 4.6e-07 29.6 0.0 0.00035 20.2 0.0 2.9 2 1 0 2 2 2 1 Ras family MMR_HSR1_Xtn PF16897.5 KEG11220.1 - 4.9e-07 29.7 0.0 0.0019 18.2 0.0 2.6 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 KEG11220.1 - 1.9e-06 28.4 0.0 0.087 13.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PduV-EutP PF10662.9 KEG11220.1 - 0.0002 21.1 0.0 0.14 11.9 0.0 3.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KEG11220.1 - 0.00067 19.0 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 Septin TniB PF05621.11 KEG11220.1 - 0.00083 18.8 0.0 0.034 13.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein GBP PF02263.19 KEG11220.1 - 0.0017 17.7 0.0 0.33 10.2 0.0 2.3 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain IIGP PF05049.13 KEG11220.1 - 0.0028 16.8 0.1 0.12 11.4 0.1 2.7 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.12 KEG11220.1 - 0.0052 16.2 0.0 1.8 7.9 0.0 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region cobW PF02492.19 KEG11220.1 - 0.0054 16.3 0.1 0.3 10.6 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KEG11220.1 - 0.019 15.5 0.0 4.2 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KEG11220.1 - 0.02 14.7 0.3 19 5.0 0.0 3.3 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_15 PF13175.6 KEG11220.1 - 0.026 14.2 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 KEG11220.1 - 0.036 13.2 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 KEG11220.1 - 0.038 13.9 0.0 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KEG11220.1 - 0.054 13.3 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEG11220.1 - 0.093 13.1 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF1154 PF06631.11 KEG11221.1 - 0.08 13.0 0.3 0.81 9.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Med9 PF07544.13 KEG11221.1 - 0.35 11.0 1.8 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PUL PF08324.11 KEG11223.1 - 0.04 13.2 0.1 0.048 12.9 0.1 1.1 1 0 0 1 1 1 0 PUL domain IF4E PF01652.18 KEG11224.1 - 1.6e-07 31.2 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glycos_transf_2 PF00535.26 KEG11224.1 - 0.017 14.9 0.0 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 PUA PF01472.20 KEG11224.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 PUA domain Nnf1 PF03980.14 KEG11225.1 - 0.16 12.4 3.7 2.8 8.3 0.5 2.8 2 0 0 2 2 2 0 Nnf1 LIDHydrolase PF10230.9 KEG11226.1 - 1.2e-61 208.7 0.1 1.3e-61 208.5 0.1 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KEG11226.1 - 3.3e-06 26.5 0.0 4.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEG11226.1 - 0.00025 21.7 0.0 0.00045 20.9 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEG11226.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KEG11226.1 - 0.16 11.6 0.4 2.3 7.8 0.6 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KEG11226.1 - 0.25 11.4 1.9 1.1 9.3 1.9 2.0 1 1 0 1 1 1 0 Thioesterase domain SIR2 PF02146.17 KEG11227.1 - 7.6e-59 198.6 0.0 1e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Sporozoite_P67 PF05642.11 KEG11227.1 - 0.0083 14.3 2.3 0.01 14.0 2.3 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Serglycin PF04360.12 KEG11227.1 - 5 7.0 8.0 13 5.8 8.0 1.8 1 1 0 1 1 1 0 Serglycin PI3_PI4_kinase PF00454.27 KEG11228.1 - 0.0065 16.3 0.1 0.051 13.4 0.2 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase eRF1_1 PF03463.15 KEG11229.1 - 8.4e-34 116.4 0.0 1.4e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KEG11229.1 - 4.9e-16 59.2 0.0 3.2e-15 56.6 0.0 2.3 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.15 KEG11229.1 - 1.1e-15 58.1 0.2 1.8e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 2 baeRF_family3 PF18845.1 KEG11229.1 - 0.00054 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 YqgC PF17430.2 KEG11229.1 - 0.37 10.9 1.2 0.77 9.9 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized YqgC-like NifU PF01106.17 KEG11230.1 - 7e-27 93.4 0.0 1.6e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 KEG11230.1 - 4.1e-21 74.8 0.0 7.6e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Abhydrolase_1 PF00561.20 KEG11231.1 - 1.8e-18 67.1 0.0 1.1e-11 44.9 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG11231.1 - 3.1e-13 49.6 0.0 1.9e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEG11231.1 - 5.3e-06 27.2 0.0 7.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KEG11231.1 - 6.3e-05 22.9 0.0 0.0038 17.1 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 KEG11231.1 - 0.00029 19.6 0.0 0.0004 19.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KEG11231.1 - 0.00029 20.4 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEG11231.1 - 0.00069 19.3 0.0 0.0025 17.4 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 KEG11231.1 - 0.019 14.5 0.1 3.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Thioesterase PF00975.20 KEG11231.1 - 0.021 15.0 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.9 KEG11231.1 - 0.023 13.8 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Esterase PF00756.20 KEG11231.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KEG11231.1 - 0.034 13.7 0.1 2 7.9 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KEG11231.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KEG11231.1 - 0.21 11.2 0.1 0.49 10.0 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KEG11232.1 - 1e-19 71.2 0.0 1e-18 67.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG11232.1 - 2.7e-10 39.9 0.0 5.3e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEG11232.1 - 9.2e-10 39.5 0.3 1.4e-09 38.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KEG11232.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 KEG11232.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KEG11232.1 - 0.11 12.3 0.1 0.45 10.3 0.1 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Kinesin PF00225.23 KEG11235.1 - 7.6e-17 61.2 0.0 5.7e-16 58.4 0.0 2.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG11235.1 - 0.00027 20.9 0.0 10 6.1 0.0 3.3 2 1 1 3 3 3 3 Microtubule binding UCH PF00443.29 KEG11236.1 - 1.8e-28 99.8 0.0 4.7e-28 98.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG11236.1 - 3.7e-12 46.5 0.2 6.4e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin_2 PF18073.1 KEG11236.1 - 0.16 11.7 4.3 0.13 12.1 1.8 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Kinesin PF00225.23 KEG11237.1 - 4.8e-86 288.7 0.0 7.4e-86 288.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG11237.1 - 4.2e-24 85.2 0.0 1.4e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Calpain_III PF01067.22 KEG11237.1 - 5.2e-15 55.9 0.0 2.7e-12 47.1 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III Arm PF00514.23 KEG11237.1 - 1.3e-08 34.5 0.6 0.037 14.1 0.1 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KEG11237.1 - 0.07 13.5 0.5 4.1 7.9 0.2 2.9 1 1 1 2 2 2 0 HEAT repeats TipAS PF07739.13 KEG11237.1 - 1.9 9.1 5.8 9.1 6.9 0.0 3.4 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain Ribosomal_L29 PF00831.23 KEG11237.1 - 6.2 6.9 12.1 0.47 10.5 0.6 3.2 3 0 0 3 3 3 0 Ribosomal L29 protein THOC2_N PF16134.5 KEG11238.1 - 0.1 11.2 2.6 0.076 11.6 0.5 1.6 1 1 1 2 2 2 0 THO complex subunit 2 N-terminus BUD22 PF09073.10 KEG11240.1 - 0.062 12.6 9.1 0.16 11.3 9.1 1.7 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 KEG11240.1 - 0.14 12.4 2.4 0.3 11.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Spt5_N PF11942.8 KEG11240.1 - 1.4 10.0 9.6 29 5.7 4.6 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal MID_MedPIWI PF18296.1 KEG11240.1 - 1.6 8.5 6.6 3.3 7.4 0.2 2.9 2 0 0 2 2 2 0 MID domain of medPIWI dUTPase_2 PF08761.11 KEG11241.1 - 5.7e-48 163.2 0.0 7.6e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase Ribosomal_L23 PF00276.20 KEG11242.1 - 4.1e-16 59.1 3.7 4.1e-16 59.1 3.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 TusA PF01206.17 KEG11242.1 - 0.056 13.3 1.2 0.07 13.0 0.1 1.7 2 0 0 2 2 2 0 Sulfurtransferase TusA Ribosomal_L23 PF00276.20 KEG11243.1 - 4.1e-16 59.1 3.7 4.1e-16 59.1 3.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 TusA PF01206.17 KEG11243.1 - 0.056 13.3 1.2 0.07 13.0 0.1 1.7 2 0 0 2 2 2 0 Sulfurtransferase TusA PHD PF00628.29 KEG11245.1 - 0.00076 19.3 3.2 0.00076 19.3 3.2 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KEG11245.1 - 0.017 14.7 2.8 0.034 13.7 2.8 1.6 1 0 0 1 1 1 0 PHD-finger FKBP_C PF00254.28 KEG11247.1 - 2.9e-29 101.2 0.0 3.4e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MIP PF00230.20 KEG11248.1 - 1.6e-25 90.2 19.3 1.9e-24 86.7 16.4 2.7 1 1 1 2 2 2 1 Major intrinsic protein Peptidase_U4 PF03419.13 KEG11248.1 - 0.66 9.2 11.3 1.4 8.1 11.2 1.8 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Deltameth_res PF16020.5 KEG11248.1 - 1.5 8.8 8.1 2.8 7.9 0.2 3.9 3 0 0 3 3 3 0 Deltamethrin resistance EF-hand_1 PF00036.32 KEG11249.1 - 2.8e-30 101.6 7.9 1.6e-08 33.5 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KEG11249.1 - 1.6e-26 92.5 1.4 2e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG11249.1 - 7.8e-23 80.1 6.6 7.1e-11 41.8 0.3 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KEG11249.1 - 6.5e-22 75.5 3.3 5.7e-07 29.0 0.1 4.6 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KEG11249.1 - 9.5e-19 66.0 7.1 1.7e-05 24.1 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KEG11249.1 - 2.9e-09 37.1 0.1 4.1e-08 33.4 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KEG11249.1 - 7.4e-07 29.1 2.7 0.051 13.5 0.9 3.1 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 KEG11249.1 - 0.015 15.4 0.9 4.6 7.4 0.1 2.9 2 2 0 2 2 2 0 Ca2+ insensitive EF hand DUF3911 PF13050.6 KEG11249.1 - 0.027 14.6 0.6 0.084 13.0 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3911) SPARC_Ca_bdg PF10591.9 KEG11249.1 - 0.1 13.0 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MORN PF02493.20 KEG11250.1 - 3.4e-47 155.6 80.2 1.1e-05 25.0 0.5 12.5 12 0 0 12 12 12 12 MORN repeat Ribosomal_L28e PF01778.17 KEG11252.1 - 6.3e-29 101.1 0.0 1.1e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KEG11252.1 - 2.1e-15 57.2 20.7 6.8e-15 55.5 20.6 2.0 1 1 0 1 1 1 1 Mak16 protein C-terminal region DNA_pack_C PF02499.15 KEG11253.1 - 0.055 12.4 0.4 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Probable DNA packing protein, C-terminus DUF3145 PF11343.8 KEG11253.1 - 0.15 11.6 1.1 0.78 9.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) polyprenyl_synt PF00348.17 KEG11254.1 - 1.8e-78 263.1 0.4 1.9e-66 223.8 0.2 3.0 1 1 1 2 2 2 2 Polyprenyl synthetase DHHC PF01529.20 KEG11255.1 - 1.4e-30 106.2 9.0 1.4e-30 106.2 9.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase PMT_4TMC PF16192.5 KEG11255.1 - 0.98 9.0 6.3 0.84 9.2 2.6 2.1 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Wzy_C_2 PF11846.8 KEG11255.1 - 5.1 7.0 12.9 13 5.6 0.7 2.7 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Methyltransf_28 PF02636.17 KEG11256.1 - 1.8e-28 99.9 0.0 2.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KEG11256.1 - 0.00011 21.3 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PRMT5 PF05185.16 KEG11256.1 - 0.00099 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 KEG11256.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEG11256.1 - 0.044 14.5 0.0 0.09 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEG11256.1 - 0.056 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 KEG11257.1 - 1.9e-16 60.5 0.0 2.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M8 PF01457.16 KEG11258.1 - 2.1e-13 49.8 0.0 2.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin FAM91_C PF14648.6 KEG11259.1 - 3.9e-116 388.4 0.0 5.6e-116 387.9 0.0 1.2 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 KEG11259.1 - 4.7e-109 364.4 0.1 6.2e-109 364.0 0.1 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Phasin_2 PF09361.10 KEG11259.1 - 5.8 7.3 8.9 23 5.3 0.2 3.2 3 0 0 3 3 3 0 Phasin protein Vps39_2 PF10367.9 KEG11260.1 - 7e-22 77.9 1.7 1.6e-21 76.7 0.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KEG11260.1 - 6.6e-15 55.3 0.1 6.2e-13 49.0 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 KEG11260.1 - 1.4e-09 38.0 0.0 8.1e-09 35.5 0.0 2.1 2 1 0 2 2 2 1 CNH domain Clathrin PF00637.20 KEG11260.1 - 4.3e-08 33.2 0.1 0.0051 16.7 0.2 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS PQQ_3 PF13570.6 KEG11260.1 - 0.072 13.6 0.0 0.26 11.8 0.0 2.0 1 0 0 1 1 1 0 PQQ-like domain zf-C3H2C3 PF17122.5 KEG11260.1 - 0.081 13.0 1.7 0.24 11.4 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger DUF2175 PF09943.9 KEG11260.1 - 0.3 11.4 1.3 1.2 9.5 1.3 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Hydrolase_4 PF12146.8 KEG11261.1 - 0.00011 21.6 0.0 0.016 14.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEG11261.1 - 0.00036 20.1 0.0 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KEG11261.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KEG11261.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 KEG11261.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KEG11261.1 - 0.073 12.9 0.0 1.2 8.9 0.0 2.3 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase SpoU_methylase PF00588.19 KEG11263.1 - 1.8e-12 47.7 0.0 1.5e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family BBS2_C PF14782.6 KEG11265.1 - 2.1e-59 201.4 2.9 2.4e-59 201.2 2.9 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal AMP-binding PF00501.28 KEG11266.1 - 8.5e-19 67.4 0.0 5.5e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme ERM PF00769.19 KEG11267.1 - 3.5 7.4 14.8 5 6.9 14.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PSP PF04046.16 KEG11268.1 - 1e-17 63.7 4.3 1.9e-17 62.8 4.3 1.5 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 KEG11268.1 - 2.5e-14 53.5 0.0 6.4e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) eIF3_subunit PF08597.10 KEG11269.1 - 0.04 13.8 0.1 0.04 13.8 0.1 2.8 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Tti2 PF10521.9 KEG11269.1 - 0.078 12.5 0.2 0.078 12.5 0.2 1.7 2 0 0 2 2 2 0 Tti2 family LMBR1 PF04791.16 KEG11270.1 - 1.2e-61 209.2 18.5 1.5e-61 208.9 18.5 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein SUKH-4 PF14435.6 KEG11270.1 - 0.23 11.5 0.6 0.43 10.6 0.6 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein RRM_1 PF00076.22 KEG11271.1 - 4e-15 55.4 0.0 5.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg14 PF08660.11 KEG11272.1 - 5.8e-57 192.4 0.2 1.3e-56 191.3 0.0 1.7 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 KEG11272.1 - 8.3e-28 97.4 0.1 8.3e-28 97.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain RskA PF10099.9 KEG11272.1 - 0.019 15.3 0.0 0.14 12.4 0.0 2.0 1 1 0 2 2 2 0 Anti-sigma-K factor rskA CobA_CobO_BtuR PF02572.15 KEG11272.1 - 0.097 12.9 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Baculo_LEF-10 PF07206.11 KEG11272.1 - 0.38 10.9 1.5 2.4 8.4 0.4 2.3 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) NatB_MDM20 PF09797.9 KEG11273.1 - 1.3e-23 83.6 0.1 4.5e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KEG11273.1 - 8.7e-07 29.4 6.8 0.011 16.2 1.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PRTP PF01366.18 KEG11273.1 - 0.0054 14.9 0.3 0.0094 14.0 0.3 1.3 1 0 0 1 1 1 1 Herpesvirus processing and transport protein TAF1_subA PF14929.6 KEG11273.1 - 0.018 14.4 0.3 0.071 12.5 0.0 2.0 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A TPR_16 PF13432.6 KEG11273.1 - 0.054 14.2 0.4 5.1 7.8 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11273.1 - 0.088 13.1 2.8 39 4.8 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG11273.1 - 0.1 12.7 0.2 5.7 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG11273.1 - 0.11 12.6 3.1 20 5.6 0.3 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG11273.1 - 0.11 12.9 2.1 9.5 6.9 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG11273.1 - 1.5 9.1 9.7 21 5.4 0.3 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KEG11273.1 - 2 8.8 11.9 13 6.1 0.1 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat PLAC8 PF04749.17 KEG11274.1 - 3.5e-12 47.2 13.7 4.8e-12 46.7 13.7 1.2 1 0 0 1 1 1 1 PLAC8 family LRR_4 PF12799.7 KEG11275.1 - 5e-09 36.3 1.0 0.00093 19.5 0.1 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11275.1 - 0.0012 18.6 2.0 0.36 10.6 0.3 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 KEG11275.1 - 0.16 12.7 0.2 50 5.0 0.1 3.4 2 0 0 2 2 2 0 Leucine Rich Repeat SAM_1 PF00536.30 KEG11276.1 - 5.8e-05 23.5 0.0 9.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KEG11276.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Proteasom_Rpn13 PF04683.13 KEG11279.1 - 3.5e-14 53.1 0.1 6.5e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pkinase PF00069.25 KEG11280.1 - 1.2e-19 70.7 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11280.1 - 3.8e-08 32.9 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.21 KEG11281.1 - 2e-78 261.8 0.2 2.3e-78 261.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KEG11281.1 - 6.5e-14 51.8 0.0 7.6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG11281.1 - 6.7e-14 52.1 0.0 9.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEG11281.1 - 1.5e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEG11281.1 - 2.2e-12 46.8 0.8 5.6e-08 32.3 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KEG11281.1 - 9.2e-10 38.3 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG11281.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KEG11281.1 - 0.0056 16.0 0.1 0.0095 15.3 0.1 1.5 1 1 0 1 1 1 1 6-phosphofructo-2-kinase ATP-grasp_4 PF13535.6 KEG11284.1 - 2.2e-15 56.6 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KEG11284.1 - 5.7e-08 33.0 0.0 1.6e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KEG11284.1 - 9.4e-06 25.7 0.1 2.3e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 KEG11284.1 - 9.7e-05 22.1 0.1 0.11 12.3 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 KEG11284.1 - 0.0022 17.5 0.0 0.024 14.2 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KEG11284.1 - 0.0033 17.2 0.2 0.016 15.0 0.2 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_N PF18130.1 KEG11284.1 - 0.028 15.0 0.1 0.06 13.9 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp N-terminal domain Dynamin_N PF00350.23 KEG11286.1 - 5.4e-16 59.1 0.0 7e-15 55.5 0.0 2.3 1 1 0 1 1 1 1 Dynamin family DUF5600 PF18150.1 KEG11286.1 - 4.9e-13 49.6 0.0 1.1e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 KEG11286.1 - 2.9e-08 33.8 0.0 8.3e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 KEG11286.1 - 4.6e-05 23.2 0.1 8.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein RsgA_GTPase PF03193.16 KEG11286.1 - 0.02 14.8 0.0 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase GET2 PF08690.10 KEG11286.1 - 1.3 8.6 18.1 2.4 7.7 18.1 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 HA2 PF04408.23 KEG11287.1 - 7.4e-18 64.8 0.1 8.4e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEG11287.1 - 2.7e-14 53.3 0.0 6.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEG11287.1 - 1.6e-11 44.5 0.0 1.1e-10 41.8 0.0 2.4 2 1 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG11287.1 - 2.1e-08 34.1 0.1 5.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KEG11287.1 - 1.9e-06 28.3 0.1 3.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG11287.1 - 1.9e-05 25.0 0.0 6.5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEG11287.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KEG11287.1 - 0.00034 20.7 0.2 0.55 10.2 0.0 2.6 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KEG11287.1 - 0.00075 19.1 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KEG11287.1 - 0.00083 18.5 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KEG11287.1 - 0.0016 18.2 0.2 1.2 8.8 0.0 2.4 1 1 0 2 2 2 2 IstB-like ATP binding protein SRP54 PF00448.22 KEG11287.1 - 0.005 16.5 0.1 0.018 14.7 0.0 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA PF00004.29 KEG11287.1 - 0.0055 17.1 0.2 0.034 14.6 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KEG11287.1 - 0.046 13.3 0.0 4.4 6.8 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KEG11287.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KEG11287.1 - 0.058 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KEG11287.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF705 PF05152.12 KEG11287.1 - 0.082 12.4 0.4 0.26 10.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF705) AAA_25 PF13481.6 KEG11287.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEG11287.1 - 0.085 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 KEG11287.1 - 0.086 12.2 0.2 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KEG11287.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEG11287.1 - 0.12 12.7 0.2 0.35 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KEG11287.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Flavi_DEAD PF07652.14 KEG11287.1 - 0.14 12.1 0.2 0.31 11.0 0.2 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.12 KEG11287.1 - 0.17 11.8 0.1 0.55 10.1 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_11 PF13086.6 KEG11287.1 - 0.27 11.0 1.4 11 5.7 0.0 3.1 3 1 1 4 4 4 0 AAA domain Kelch_3 PF13415.6 KEG11288.1 - 1e-16 60.7 3.0 0.0039 17.4 0.0 7.6 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG11288.1 - 3e-16 59.0 4.8 2.2e-05 24.5 0.0 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 KEG11288.1 - 3.7e-15 55.7 10.4 2e-05 24.5 0.0 6.5 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG11288.1 - 2.7e-14 52.4 4.9 2.8e-06 26.8 0.1 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KEG11288.1 - 5.9e-14 51.7 1.5 0.0004 20.3 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KEG11288.1 - 2.5e-13 49.4 2.0 0.026 14.5 0.0 6.8 6 0 0 6 6 6 4 Kelch motif LIN37 PF15306.6 KEG11288.1 - 0.065 13.5 0.2 0.065 13.5 0.2 2.5 3 0 0 3 3 3 0 LIN37 Glyco_hydro_65m PF03632.15 KEG11289.1 - 9e-45 153.2 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KEG11289.1 - 5.7e-06 26.1 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.6 KEG11289.1 - 0.0014 18.8 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3341 PF11821.8 KEG11290.1 - 0.33 10.6 4.3 0.43 10.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Exo_endo_phos PF03372.23 KEG11291.1 - 6.4e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc3_2 PF01498.18 KEG11291.1 - 0.14 12.5 0.5 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Transposase SET PF00856.28 KEG11292.1 - 1.4e-07 32.1 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SET domain Bac_GDH PF05088.12 KEG11292.1 - 0.028 11.9 0.0 0.041 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase UPF0181 PF03701.14 KEG11292.1 - 0.054 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) dUTPase PF00692.19 KEG11292.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 dUTPase SAS4 PF15460.6 KEG11292.1 - 2.6 8.2 6.4 3.9 7.6 4.0 2.2 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 CorA PF01544.18 KEG11293.1 - 0.012 15.0 2.2 0.027 13.8 2.2 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CDT1 PF08839.11 KEG11293.1 - 0.046 14.0 0.7 0.11 12.7 0.4 1.8 1 1 1 2 2 2 0 DNA replication factor CDT1 like Peptidase_M24 PF00557.24 KEG11294.1 - 1.3e-45 155.7 0.0 1.9e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KEG11294.1 - 3.1e-36 124.9 0.0 4.5e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KEG11294.1 - 4.1e-19 68.4 0.5 1e-18 67.1 0.1 1.9 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KEG11294.1 - 0.00024 21.8 0.0 0.0031 18.2 0.1 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain HpcH_HpaI PF03328.14 KEG11295.1 - 1.4e-58 197.6 0.0 1.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Pkinase PF00069.25 KEG11297.1 - 2.9e-58 197.3 0.0 3.4e-40 138.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11297.1 - 6e-36 124.1 0.0 3.1e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG11297.1 - 8.7e-06 24.8 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG11297.1 - 0.00017 21.0 0.0 0.065 12.5 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KEG11297.1 - 0.00067 19.1 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG11297.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG11297.1 - 0.23 11.1 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family GlcNAc_2-epim PF07221.11 KEG11298.1 - 0.089 12.0 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Kinesin PF00225.23 KEG11299.1 - 1.9e-39 135.5 0.0 2.4e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG11299.1 - 4.6e-25 88.3 0.0 6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 KEG11299.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KEG11299.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KEG11299.1 - 0.057 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain K_channel_TID PF07941.11 KEG11299.1 - 2.2 8.8 8.2 2 9.0 4.6 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Kinesin PF00225.23 KEG11300.1 - 4.9e-46 157.2 2.0 6.1e-46 156.9 0.2 2.1 2 0 0 2 2 2 1 Kinesin motor domain TMF_DNA_bd PF12329.8 KEG11300.1 - 0.0043 17.0 1.9 0.0043 17.0 1.9 6.2 6 2 2 8 8 8 1 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 KEG11300.1 - 0.062 13.5 31.0 1.3 9.2 1.2 4.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family MSA-2c PF12238.8 KEG11300.1 - 0.16 12.0 0.2 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c tRNA-synt_1c PF00749.21 KEG11300.1 - 0.36 9.7 9.3 0.016 14.2 1.6 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain YjeF_N PF03853.15 KEG11300.1 - 8.1 6.3 13.1 76 3.1 0.2 4.1 2 1 0 2 2 2 0 YjeF-related protein N-terminus Acylphosphatase PF00708.18 KEG11301.1 - 7.1e-26 90.4 0.1 8.3e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase DUF1664 PF07889.12 KEG11302.1 - 0.019 15.0 31.2 0.4 10.7 5.0 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) LXG PF04740.12 KEG11302.1 - 0.047 13.4 17.6 0.033 13.9 9.5 2.9 1 1 1 2 2 2 0 LXG domain of WXG superfamily ZapB PF06005.12 KEG11302.1 - 0.089 13.2 31.4 0.097 13.1 5.5 5.1 3 2 1 4 4 4 0 Cell division protein ZapB ADIP PF11559.8 KEG11302.1 - 0.47 10.5 36.6 0.21 11.7 9.1 3.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 KEG11302.1 - 0.59 9.7 37.1 0.58 9.7 26.9 2.2 1 1 1 2 2 2 0 Intermediate filament protein LPP PF04728.13 KEG11302.1 - 0.59 10.6 18.7 4.5 7.7 0.8 5.9 6 1 0 6 6 6 0 Lipoprotein leucine-zipper RPW8 PF05659.11 KEG11302.1 - 0.99 9.1 9.5 0.67 9.6 0.2 3.6 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.12 KEG11302.1 - 1.1 9.3 16.7 0.51 10.4 3.6 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 KEG11302.1 - 1.4 6.4 35.5 0.16 9.4 10.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Topoisom_I_N PF02919.15 KEG11302.1 - 1.8 8.0 5.6 0.53 9.8 2.0 1.9 2 1 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PfUIS3 PF11567.8 KEG11302.1 - 2 8.9 5.4 4.1 7.8 0.6 3.0 2 1 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein Syntaxin-6_N PF09177.11 KEG11302.1 - 2.7 8.6 24.4 18 6.0 7.9 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 KEG11302.1 - 5.3 7.2 32.1 4.7 7.4 9.9 4.3 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family Vps51 PF08700.11 KEG11302.1 - 5.5 7.1 14.0 1.7 8.8 2.5 4.5 1 1 1 2 2 1 0 Vps51/Vps67 DUF2203 PF09969.9 KEG11302.1 - 7.1 7.4 25.8 0.56 10.9 1.0 3.8 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) DASH_Dam1 PF08653.10 KEG11302.1 - 9.8 6.1 7.8 9.3 6.1 0.1 4.3 5 1 0 5 5 4 0 DASH complex subunit Dam1 KapB PF08810.10 KEG11302.1 - 10 6.4 10.1 2.5 8.3 2.8 3.4 2 2 3 5 5 5 0 Kinase associated protein B PIH1_CS PF18201.1 KEG11303.1 - 2.8e-08 34.1 0.2 6.9e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 PIH1 CS-like domain Lipase_3 PF01764.25 KEG11304.1 - 0.029 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) ABATE PF07336.11 KEG11308.1 - 0.39 11.4 5.7 0.41 11.3 0.5 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator EF-hand_7 PF13499.6 KEG11309.1 - 6.2e-11 42.6 0.1 0.33 11.4 0.0 4.9 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KEG11309.1 - 0.0001 22.0 0.5 0.12 12.3 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 KEG11309.1 - 0.0016 17.9 1.6 0.14 11.7 0.1 4.2 5 0 0 5 5 5 1 EF hand EF-hand_13 PF17958.1 KEG11309.1 - 0.0097 15.7 0.0 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KEG11309.1 - 0.08 12.5 0.3 0.87 9.2 0.1 2.5 2 0 0 2 2 2 0 EF hand DAGK_acc PF00609.19 KEG11311.1 - 4.1e-43 147.5 0.0 6.4e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KEG11311.1 - 4.6e-17 61.8 0.0 8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PPTA PF01239.22 KEG11312.1 - 3.1e-18 64.9 16.5 3.4e-07 29.8 0.8 5.5 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Viral_Beta_CD PF04530.12 KEG11312.1 - 0.0033 17.7 0.1 0.0073 16.6 0.1 1.5 1 0 0 1 1 1 1 Viral Beta C/D like family SRP72 PF08492.12 KEG11312.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain Fumerase_C PF05683.12 KEG11313.1 - 1.7e-87 292.1 0.0 2.9e-87 291.3 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 KEG11313.1 - 8.6e-81 271.3 0.0 1.2e-80 270.8 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) RRM_1 PF00076.22 KEG11315.1 - 7.5e-34 115.4 0.0 2.2e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KEG11315.1 - 7.5e-06 25.8 0.1 0.041 13.7 0.0 2.4 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 KEG11315.1 - 0.00026 21.0 0.4 0.75 9.9 0.0 3.5 2 2 0 2 2 2 1 Limkain b1 Spt20 PF12090.8 KEG11315.1 - 0.00055 19.6 5.4 0.00074 19.2 5.4 1.2 1 0 0 1 1 1 1 Spt20 family RRM_5 PF13893.6 KEG11315.1 - 0.00099 18.7 2.9 0.35 10.5 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 KEG11315.1 - 0.0011 19.0 1.5 0.0011 19.0 1.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRM_7 PF16367.5 KEG11315.1 - 0.0033 17.5 0.9 0.13 12.4 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif DUF2722 PF10846.8 KEG11315.1 - 0.015 14.3 5.3 0.018 14.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RRM_3 PF08777.11 KEG11315.1 - 0.12 12.4 1.3 1.6 8.9 0.8 2.6 2 1 0 2 2 2 0 RNA binding motif GRP PF07172.11 KEG11315.1 - 0.66 10.7 8.1 1.4 9.6 8.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_L11_N PF03946.14 KEG11316.1 - 9.9e-17 60.5 1.4 1.1e-16 60.4 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KEG11316.1 - 1.4e-12 48.0 0.4 3.1e-12 46.8 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Torsin PF06309.11 KEG11317.1 - 8.5e-05 22.7 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 KEG11317.1 - 0.00025 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KEG11317.1 - 0.0035 17.2 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 KEG11317.1 - 0.0064 16.5 0.0 0.037 14.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KEG11317.1 - 0.014 15.2 0.2 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KEG11317.1 - 0.045 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KEG11317.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 KEG11317.1 - 0.083 12.2 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KEG11317.1 - 0.093 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KEG11317.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KEG11317.1 - 0.18 12.3 0.1 0.89 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEG11317.1 - 0.25 11.8 0.0 0.46 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SpoIISA_toxin PF14171.6 KEG11318.1 - 0.082 12.6 2.2 0.12 12.0 2.2 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2070 PF09843.9 KEG11318.1 - 0.54 8.5 6.1 0.56 8.4 6.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FA_desaturase PF00487.24 KEG11320.1 - 3.2e-17 63.2 21.1 4.2e-17 62.8 21.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEG11320.1 - 1.3e-05 25.3 0.2 9.1e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 KEG11321.1 - 3.4e-51 170.1 32.7 2.8e-08 34.3 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG11321.1 - 2.8e-18 66.0 4.4 0.0029 17.9 0.0 6.1 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KEG11321.1 - 6.6e-12 45.8 0.0 1.2e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KEG11321.1 - 5.9e-07 28.7 0.0 0.06 12.3 0.0 3.8 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEG11321.1 - 0.00014 21.3 0.0 1.7 7.9 0.0 3.6 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 KEG11321.1 - 0.00059 19.2 0.6 0.29 10.4 0.0 3.5 2 2 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KEG11321.1 - 0.0015 18.4 8.7 5.5 7.0 0.0 5.9 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Frtz PF11768.8 KEG11321.1 - 0.17 10.2 0.0 3 6.0 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DEAD_2 PF06733.15 KEG11322.1 - 1.6e-41 141.8 0.0 4.2e-41 140.5 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 KEG11322.1 - 2.3e-39 135.3 0.0 5.5e-39 134.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 KEG11322.1 - 7.1e-36 123.7 2.0 2.4e-30 105.7 0.5 2.9 3 0 0 3 3 3 2 Helical and beta-bridge domain DEAD PF00270.29 KEG11322.1 - 6.1e-05 22.9 0.3 0.017 14.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KEG11322.1 - 0.0018 18.3 0.3 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KEG11322.1 - 0.0036 17.6 0.0 0.02 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEG11322.1 - 0.017 15.4 3.0 0.044 14.1 0.1 3.1 4 1 0 4 4 4 0 AAA domain Flavi_DEAD PF07652.14 KEG11322.1 - 0.076 13.0 0.2 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_11 PF13086.6 KEG11322.1 - 0.13 12.1 0.3 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cullin PF00888.22 KEG11323.1 - 7.6e-92 308.9 8.6 1e-91 308.5 8.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEG11323.1 - 7.5e-23 80.3 1.1 2.8e-22 78.5 1.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Gp-FAR-1 PF05823.12 KEG11323.1 - 0.037 14.4 0.2 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF724 PF05266.14 KEG11325.1 - 0.026 14.3 7.2 0.082 12.7 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FemAB PF02388.16 KEG11325.1 - 0.052 12.4 2.6 0.32 9.8 2.5 1.9 1 1 0 1 1 1 0 FemAB family DUF1664 PF07889.12 KEG11325.1 - 0.16 12.1 3.3 12 5.9 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KEG11325.1 - 0.16 12.6 5.2 0.38 11.4 0.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 KEG11325.1 - 0.17 12.0 1.9 5.9 7.0 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 MAD PF05557.13 KEG11325.1 - 0.27 9.5 11.8 15 3.8 12.5 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein APG6_N PF17675.1 KEG11325.1 - 0.58 10.7 15.0 0.35 11.4 6.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region IFP_35_N PF07334.13 KEG11325.1 - 0.98 9.5 4.0 6.7 6.9 1.4 2.9 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pkinase PF00069.25 KEG11326.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11326.1 - 1e-40 139.7 0.0 1.3e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11326.1 - 0.00018 21.0 0.0 0.00084 18.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KEG11326.1 - 0.0065 16.1 0.0 1.5 8.4 0.0 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KEG11326.1 - 0.01 14.7 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KEG11326.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEG11326.1 - 0.15 11.6 0.1 2.1 7.9 0.1 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase U79_P34 PF03064.16 KEG11327.1 - 6 6.1 11.7 15 4.8 11.7 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GAGA_bind PF06217.12 KEG11327.1 - 6.2 7.0 7.7 9.8 6.4 7.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Adhesin_P1 PF03257.13 KEG11329.1 - 0.079 13.5 1.2 0.5 10.9 0.3 2.3 1 1 1 2 2 2 0 Mycoplasma adhesin P1 A_deaminase_N PF08451.11 KEG11330.1 - 0.042 14.2 0.4 0.088 13.1 0.4 1.5 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DUF743 PF05332.11 KEG11330.1 - 0.12 12.4 0.2 0.38 10.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Hydrolase_4 PF12146.8 KEG11331.1 - 4.4e-69 232.4 0.0 5.6e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG11331.1 - 4.5e-11 42.9 0.0 7.5e-10 38.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEG11331.1 - 2.9e-10 41.1 1.3 3.7e-10 40.8 0.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KEG11331.1 - 1.3e-06 28.1 0.0 0.00082 18.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KEG11331.1 - 0.00035 20.3 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 KEG11331.1 - 0.00079 19.0 0.0 0.0048 16.5 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KEG11331.1 - 0.0075 16.1 0.1 0.031 14.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KEG11331.1 - 0.022 14.5 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KEG11331.1 - 0.03 13.9 0.0 0.15 11.6 0.1 2.0 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 KEG11331.1 - 0.031 14.0 0.0 0.092 12.4 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein BAAT_C PF08840.11 KEG11331.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KEG11331.1 - 0.071 12.9 0.0 5.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KEG11331.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 KEG11331.1 - 0.17 10.7 0.0 0.44 9.4 0.0 1.5 1 1 1 2 2 2 0 Chlorophyllase enzyme Peptidase_S10 PF00450.22 KEG11331.1 - 0.25 10.7 0.0 2.2 7.6 0.0 1.9 2 0 0 2 2 2 0 Serine carboxypeptidase LRR_4 PF12799.7 KEG11332.1 - 2.7e-06 27.6 0.9 0.084 13.3 0.4 4.5 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11332.1 - 0.0027 17.5 1.6 1 9.1 0.0 4.2 3 2 2 5 5 5 1 Leucine rich repeat LRR_6 PF13516.6 KEG11332.1 - 0.063 13.3 7.6 1.4 9.1 0.4 4.3 4 0 0 4 4 4 0 Leucine Rich repeat EMP24_GP25L PF01105.24 KEG11333.1 - 1.7e-33 116.1 0.1 2.3e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 KEG11333.1 - 0.14 12.6 0.6 0.22 12.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4498 PF14926.6 KEG11334.1 - 2.4e-21 76.2 0.0 2.9e-14 53.0 0.0 4.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4498) Metallophos PF00149.28 KEG11335.1 - 5.7e-15 56.4 0.0 8.6e-15 55.8 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEG11335.1 - 2.9e-07 30.8 0.0 7.6e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CutA1 PF03091.15 KEG11336.1 - 1.7e-20 72.7 1.0 2e-20 72.5 1.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein TACC_C PF05010.14 KEG11337.1 - 9e-05 22.4 3.4 0.00014 21.7 3.4 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 KEG11337.1 - 0.0067 16.7 3.1 0.014 15.7 2.2 1.9 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup88 PF10168.9 KEG11337.1 - 0.085 10.7 1.5 0.11 10.3 1.5 1.1 1 0 0 1 1 1 0 Nuclear pore component Spc7 PF08317.11 KEG11337.1 - 0.085 11.7 7.5 0.34 9.7 6.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2951 PF11166.8 KEG11337.1 - 0.11 12.7 0.9 0.2 11.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF1664 PF07889.12 KEG11337.1 - 0.12 12.4 5.5 0.57 10.2 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KEG11337.1 - 0.12 12.4 3.8 0.19 11.7 3.0 1.6 1 1 0 1 1 1 0 Laminin Domain II Noelin-1 PF12308.8 KEG11337.1 - 0.13 12.2 0.3 0.32 11.0 0.2 1.7 1 1 0 1 1 1 0 Neurogenesis glycoprotein DivIC PF04977.15 KEG11337.1 - 0.15 11.9 0.9 0.79 9.5 0.0 2.4 1 1 2 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 KEG11337.1 - 0.18 12.0 3.3 0.41 10.8 3.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KEG11337.1 - 0.2 11.7 10.8 0.77 9.8 8.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 KEG11337.1 - 0.26 10.1 6.5 0.4 9.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.9 KEG11337.1 - 1 8.4 6.1 2.5 7.1 6.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 KEG11337.1 - 1.1 9.3 11.8 46 4.1 0.0 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.11 KEG11337.1 - 3 7.9 8.1 5.1 7.2 0.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 KEG11337.1 - 7.5 6.9 6.5 6.4 7.1 4.2 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SET PF00856.28 KEG11338.1 - 2.1e-06 28.2 0.0 4.6e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 SET domain Galactosyl_T PF01762.21 KEG11339.1 - 3.8e-09 36.6 0.0 3.8e-05 23.6 0.0 3.5 2 1 0 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.21 KEG11340.1 - 0.045 13.6 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Galactosyltransferase Nmad5 PF18757.1 KEG11341.1 - 0.011 15.9 1.8 0.011 15.9 1.8 1.8 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 GAS PF13851.6 KEG11341.1 - 0.024 14.0 14.7 0.015 14.7 10.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SF-assemblin PF06705.11 KEG11341.1 - 0.025 13.9 9.0 0.045 13.1 8.5 1.6 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF3410 PF11890.8 KEG11341.1 - 0.068 13.0 1.4 0.2 11.4 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Seryl_tRNA_N PF02403.22 KEG11341.1 - 0.16 12.3 5.7 0.078 13.2 1.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 KEG11341.1 - 0.44 11.2 18.1 0.86 10.2 3.6 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HALZ PF02183.18 KEG11341.1 - 0.54 10.5 5.5 18 5.7 2.9 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Bap31_Bap29_C PF18035.1 KEG11341.1 - 1.1 9.4 7.2 0.4 10.7 0.4 2.8 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain FapA PF03961.13 KEG11341.1 - 1.7 7.2 6.9 0.42 9.1 2.0 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DivIC PF04977.15 KEG11341.1 - 2.1 8.1 10.9 2.1 8.2 0.1 3.7 2 1 2 4 4 4 0 Septum formation initiator DUF16 PF01519.16 KEG11341.1 - 3.1 8.3 7.9 2.6 8.6 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function DUF16 Fungal_TACC PF12709.7 KEG11341.1 - 6.6 7.2 7.9 29 5.2 1.4 3.1 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4271 PF14093.6 KEG11342.1 - 0.033 14.1 9.5 0.043 13.7 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) GalKase_gal_bdg PF10509.9 KEG11343.1 - 5.8e-15 54.6 1.0 1.1e-14 53.7 0.1 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KEG11343.1 - 8.5e-08 32.5 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KEG11343.1 - 0.00077 19.6 0.0 0.0031 17.7 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain MFS_1 PF07690.16 KEG11344.1 - 5.7e-09 35.4 38.5 5.7e-09 35.4 38.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily HTH_49 PF18010.1 KEG11344.1 - 0.18 11.7 0.4 5.3 7.0 0.0 2.9 2 0 0 2 2 2 0 Cry35Ab1 HTH C-terminal domain Acyl-CoA_dh_1 PF00441.24 KEG11345.1 - 3.4e-39 134.4 6.1 4.8e-39 134.0 6.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEG11345.1 - 1e-27 97.0 0.0 3.7e-27 95.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEG11345.1 - 6.7e-24 83.9 0.0 1.3e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEG11345.1 - 5.5e-20 72.0 0.3 9e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KEG11345.1 - 0.037 13.7 0.4 0.18 11.4 0.4 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal SNARE PF05739.19 KEG11346.1 - 1.2e-12 47.6 0.2 2.5e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KEG11346.1 - 2.7e-05 23.9 16.9 4.1e-05 23.3 16.9 1.3 1 0 0 1 1 1 1 Syntaxin Epsilon_antitox PF08998.11 KEG11346.1 - 0.0061 16.8 1.7 0.012 15.8 0.3 2.2 2 0 0 2 2 2 1 Bacterial epsilon antitoxin Syntaxin-5_N PF11416.8 KEG11346.1 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain SmpA_OmlA PF04355.13 KEG11346.1 - 0.11 12.3 0.1 0.4 10.5 0.1 1.9 1 0 0 1 1 1 0 SmpA / OmlA family YqeY PF09424.10 KEG11346.1 - 0.12 12.4 8.9 0.11 12.6 1.0 2.3 1 1 0 2 2 2 0 Yqey-like protein NAPRTase_C PF17956.1 KEG11346.1 - 3.7 8.0 7.6 13 6.3 0.6 3.0 2 2 1 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain BTB_2 PF02214.22 KEG11348.1 - 1.1e-16 60.9 0.0 1.9e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KEG11348.1 - 1.3e-05 25.2 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TRAPPC9-Trs120 PF08626.11 KEG11349.1 - 1.2e-05 22.9 0.5 0.00031 18.3 0.0 3.1 2 2 1 3 3 3 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ART PF01129.18 KEG11349.1 - 0.041 13.2 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase BTB_2 PF02214.22 KEG11350.1 - 3.8e-08 33.6 0.2 1.8e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain HSBP1 PF06825.12 KEG11351.1 - 8.9e-28 95.9 4.9 1.1e-27 95.6 4.9 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 EspB PF05802.11 KEG11351.1 - 0.00021 21.4 0.3 0.00024 21.2 0.3 1.1 1 0 0 1 1 1 1 Enterobacterial EspB protein IL11 PF07400.11 KEG11351.1 - 0.0038 16.9 0.3 0.013 15.2 0.3 1.6 1 1 1 2 2 2 1 Interleukin 11 CLZ PF16526.5 KEG11351.1 - 0.0076 16.6 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF935 PF06074.12 KEG11351.1 - 0.01 14.6 0.8 0.011 14.5 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) BLOC1_2 PF10046.9 KEG11351.1 - 0.011 16.1 0.4 0.054 13.8 0.4 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FtsK_SpoIIIE PF01580.18 KEG11351.1 - 0.012 15.0 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Fzo_mitofusin PF04799.13 KEG11351.1 - 0.027 14.0 0.5 0.031 13.8 0.5 1.1 1 0 0 1 1 1 0 fzo-like conserved region FANCI_S2 PF14676.6 KEG11351.1 - 0.031 14.6 0.2 0.043 14.1 0.2 1.3 1 1 0 1 1 1 0 FANCI solenoid 2 Apolipoprotein PF01442.18 KEG11351.1 - 0.034 14.0 0.3 0.04 13.8 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KEG11351.1 - 0.041 13.9 0.2 0.05 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CorA PF01544.18 KEG11351.1 - 0.047 13.0 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GAS PF13851.6 KEG11351.1 - 0.052 12.9 0.3 0.062 12.7 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IL13 PF03487.13 KEG11351.1 - 0.053 13.3 0.0 0.09 12.6 0.0 1.4 2 0 0 2 2 2 0 Interleukin-13 YvrJ PF12841.7 KEG11351.1 - 0.053 13.0 0.4 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 YvrJ protein family Serine_rich PF08824.10 KEG11351.1 - 0.065 13.2 0.1 0.072 13.1 0.1 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain CDI PF02234.19 KEG11351.1 - 0.11 12.7 0.2 0.23 11.7 0.2 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Allexi_40kDa PF05549.11 KEG11351.1 - 0.12 11.8 0.3 0.12 11.8 0.3 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ank_3 PF13606.6 KEG11352.1 - 2.9e-19 67.1 0.3 2.4e-05 24.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KEG11352.1 - 4.7e-19 68.8 0.2 6.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG11352.1 - 3e-18 65.9 2.3 5.6e-10 39.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KEG11352.1 - 2.1e-17 62.7 0.5 7.1e-07 29.4 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KEG11352.1 - 1.2e-14 54.2 0.5 1.3e-07 31.8 0.1 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) AAA PF00004.29 KEG11353.1 - 9.5e-29 100.5 0.0 2.3e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 KEG11353.1 - 8.4e-08 32.1 1.4 0.00028 20.6 0.0 4.1 2 2 1 4 4 4 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 KEG11353.1 - 5.4e-07 30.0 0.1 0.001 19.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KEG11353.1 - 2.7e-06 27.0 0.0 0.001 18.7 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KEG11353.1 - 5.5e-06 26.9 0.0 0.0048 17.3 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KEG11353.1 - 1.4e-05 25.3 0.0 0.45 10.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KEG11353.1 - 1.9e-05 24.7 0.0 0.00044 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEG11353.1 - 8.6e-05 22.9 0.0 0.078 13.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KEG11353.1 - 0.00013 21.3 0.0 0.041 13.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KEG11353.1 - 0.00024 20.9 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 KEG11353.1 - 0.00031 20.3 0.1 0.012 15.0 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein AAA_5 PF07728.14 KEG11353.1 - 0.00069 19.6 0.0 0.21 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG11353.1 - 0.00091 19.0 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KEG11353.1 - 0.00099 18.4 0.1 1.8 7.7 0.0 3.2 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KEG11353.1 - 0.0019 17.9 0.0 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KEG11353.1 - 0.0026 18.3 0.0 2.3 8.8 0.0 3.9 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 KEG11353.1 - 0.0026 17.5 0.5 2 8.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KEG11353.1 - 0.0038 16.6 0.1 0.24 10.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KEG11353.1 - 0.0051 17.4 0.0 0.33 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEG11353.1 - 0.0055 16.6 0.0 0.55 10.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 KEG11353.1 - 0.0058 17.2 0.1 0.27 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 KEG11353.1 - 0.0068 15.4 1.8 0.33 9.8 0.1 3.5 4 0 0 4 4 4 1 AAA-like domain AAA_30 PF13604.6 KEG11353.1 - 0.011 15.5 0.0 5.6 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KEG11353.1 - 0.015 14.9 0.9 2.2 7.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KEG11353.1 - 0.03 14.2 0.2 1.4 8.8 0.0 3.0 4 0 0 4 4 3 0 RsgA GTPase AAA_2 PF07724.14 KEG11353.1 - 0.057 13.5 0.0 0.68 10.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) T2SSE PF00437.20 KEG11353.1 - 0.058 12.4 0.0 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 KEG11353.1 - 0.066 12.9 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG11353.1 - 0.09 12.8 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 KEG11353.1 - 0.14 12.1 0.1 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase zf-CCHC_4 PF14392.6 KEG11354.1 - 0.0091 15.7 0.2 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KEG11354.1 - 0.1 12.7 0.7 0.2 11.8 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KEG11354.1 - 3.6 7.4 5.8 0.44 10.3 1.7 1.6 2 0 0 2 2 2 0 C2H2 zinc-finger Rhodanese PF00581.20 KEG11355.1 - 4.7e-11 43.2 0.0 5.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain AAA_12 PF13087.6 KEG11356.1 - 7.2e-52 175.9 0.0 1.4e-51 175.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEG11356.1 - 3e-40 138.7 5.1 1.6e-20 74.0 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 KEG11356.1 - 5.4e-10 39.3 0.0 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEG11356.1 - 1.1e-07 32.3 0.0 3.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KEG11356.1 - 5.9e-05 22.7 0.1 0.0044 16.6 0.0 3.1 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KEG11356.1 - 0.022 14.7 0.0 0.26 11.3 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF240 PF03086.14 KEG11356.1 - 0.047 13.6 0.5 0.096 12.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF240) Helicase_RecD PF05127.14 KEG11356.1 - 0.069 13.0 2.8 1.9 8.3 0.0 3.3 4 0 0 4 4 4 0 Helicase AAA_16 PF13191.6 KEG11356.1 - 0.074 13.4 0.8 0.94 9.8 0.0 3.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KEG11356.1 - 0.081 13.2 2.1 0.3 11.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KEG11356.1 - 0.086 13.1 0.0 0.69 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEG11356.1 - 0.27 11.7 4.0 2.3 8.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain IBR PF01485.21 KEG11357.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.5 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Bromodomain PF00439.25 KEG11358.1 - 8.2e-16 57.8 0.0 3.1e-10 40.0 0.0 3.1 3 1 0 3 3 3 2 Bromodomain DUF3909 PF13077.6 KEG11358.1 - 0.003 17.7 0.1 0.0087 16.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3909) BSD PF03909.17 KEG11358.1 - 0.098 12.7 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 BSD domain MRG PF05712.13 KEG11358.1 - 0.15 11.4 1.2 0.46 9.8 0.0 2.5 3 0 0 3 3 3 0 MRG DUF5442 PF17514.2 KEG11358.1 - 0.16 12.2 0.3 26 5.0 0.0 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5442) Ndc1_Nup PF09531.10 KEG11358.1 - 0.44 9.2 2.6 0.87 8.2 2.6 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Adaptin_N PF01602.20 KEG11361.1 - 2.8e-98 329.8 7.0 3.3e-98 329.5 7.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KEG11361.1 - 9e-15 55.0 0.2 1.7e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.23 KEG11361.1 - 0.17 11.9 1.6 1.4e+02 2.7 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HECT PF00632.25 KEG11362.1 - 1e-48 166.4 0.0 2e-48 165.5 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 KEG11362.1 - 9.8e-05 22.9 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 WWE domain Xpo1 PF08389.12 KEG11362.1 - 0.094 12.8 0.1 8.9 6.4 0.0 2.8 2 0 0 2 2 2 0 Exportin 1-like protein eRF1_1 PF03463.15 KEG11362.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 eRF1 domain 1 DivIC PF04977.15 KEG11363.1 - 0.072 12.9 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator FXMRP1_C_core PF12235.8 KEG11363.1 - 2.5 8.7 8.8 2 9.1 4.3 2.1 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal PI3_PI4_kinase PF00454.27 KEG11364.1 - 1.4e-53 182.3 0.4 3.1e-53 181.2 0.0 1.8 2 0 0 2 2 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KEG11364.1 - 5e-27 95.0 0.3 1.4e-26 93.6 0.3 1.8 1 1 0 1 1 1 1 FAT domain FRB_dom PF08771.11 KEG11364.1 - 2.3e-16 60.0 2.5 2.6e-16 59.8 0.2 2.5 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 KEG11364.1 - 1.5e-13 51.0 10.6 6.7e-13 48.8 0.3 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FATC PF02260.20 KEG11364.1 - 6e-13 48.4 0.1 1.4e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain PDZ PF00595.24 KEG11364.1 - 1.9e-06 28.1 0.7 4.6e-06 26.9 0.7 1.6 1 0 0 1 1 1 1 PDZ domain HEAT_2 PF13646.6 KEG11364.1 - 5.5e-06 26.7 3.5 0.025 15.0 0.2 4.1 2 1 0 2 2 2 2 HEAT repeats PDZ_6 PF17820.1 KEG11364.1 - 4.1e-05 23.3 0.3 0.00012 21.8 0.3 1.8 1 0 0 1 1 1 1 PDZ domain TPR_11 PF13414.6 KEG11364.1 - 0.00023 20.8 0.0 0.001 18.7 0.0 2.2 1 0 0 1 1 1 1 TPR repeat PDZ_2 PF13180.6 KEG11364.1 - 0.0005 20.3 0.1 0.0014 18.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KEG11364.1 - 0.0033 17.4 0.2 0.0084 16.1 0.2 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain HEAT PF02985.22 KEG11364.1 - 0.012 15.8 3.5 0.27 11.6 0.1 4.5 5 0 0 5 5 3 0 HEAT repeat DUF4080 PF13311.6 KEG11364.1 - 0.12 12.5 0.8 0.35 11.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) DUF1358 PF07096.11 KEG11364.1 - 0.16 11.9 0.0 0.54 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) LBP_BPI_CETP PF01273.25 KEG11365.1 - 0.0022 17.6 0.5 0.0075 15.9 0.1 2.0 2 1 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain NIF PF03031.18 KEG11366.1 - 2.8e-24 85.7 0.0 3.7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 KEG11366.1 - 7e-08 32.3 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Hydrolase PF00702.26 KEG11366.1 - 0.093 13.0 0.0 9.3 6.5 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEG11366.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEG11366.1 - 0.14 12.6 0.7 0.57 10.6 0.7 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PABP PF00658.18 KEG11367.1 - 1.6e-26 92.3 0.1 1.9e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain LON_substr_bdg PF02190.16 KEG11367.1 - 0.021 14.7 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Metal_resist PF13801.6 KEG11367.1 - 0.054 13.7 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance AIG1 PF04548.16 KEG11367.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 AIG1 family TB2_DP1_HVA22 PF03134.19 KEG11368.1 - 0.046 13.7 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Sas10_Utp3 PF04000.15 KEG11368.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Sas10/Utp3/C1D family GTP_EFTU PF00009.27 KEG11369.1 - 5.6e-40 137.0 0.1 8.5e-38 129.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEG11369.1 - 1.7e-09 38.0 0.1 4.4e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KEG11369.1 - 0.00019 21.5 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG11369.1 - 0.00092 18.8 0.1 0.0064 16.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.25 KEG11369.1 - 0.0043 17.4 0.6 0.033 14.6 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF2009 PF09418.10 KEG11370.1 - 1.5e-173 578.1 0.0 1.7e-173 577.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.14 KEG11371.1 - 3.7e-11 43.7 0.4 4.5e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 BBS1 PF14779.6 KEG11372.1 - 1.6e-84 283.3 0.0 3.1e-84 282.4 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 KEG11372.1 - 1.8e-07 31.1 0.0 0.22 11.6 0.0 3.7 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 KEG11372.1 - 0.00019 20.9 0.0 0.0035 16.8 0.0 2.4 3 0 0 3 3 3 1 PTHB1 N-terminus Mcl1_mid PF12341.8 KEG11372.1 - 0.0091 15.4 0.5 0.094 12.1 0.1 2.7 2 1 2 4 4 4 1 Minichromosome loss protein, Mcl1, middle region VMA21 PF09446.10 KEG11373.1 - 0.00021 21.3 10.4 0.00029 20.9 10.4 1.2 1 0 0 1 1 1 1 VMA21-like domain UL45 PF05473.12 KEG11373.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like RseC_MucC PF04246.12 KEG11373.1 - 3.8 7.5 5.6 6.2 6.8 5.6 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Nucleotid_trans PF03407.16 KEG11374.1 - 6.2e-47 160.3 0.2 9e-47 159.8 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Oxidored_FMN PF00724.20 KEG11375.1 - 2.7e-64 217.6 0.0 3.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CHCH PF06747.13 KEG11377.1 - 9.9e-05 22.4 8.6 0.0069 16.5 5.5 2.4 2 1 0 2 2 2 2 CHCH domain MTCP1 PF08991.10 KEG11377.1 - 0.00019 21.6 6.9 0.022 15.0 1.6 2.2 2 0 0 2 2 2 2 Mature-T-Cell Proliferation I type CX9C PF16860.5 KEG11377.1 - 0.029 14.4 4.3 0.029 14.4 4.3 2.6 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 KEG11377.1 - 0.55 10.6 6.0 9.5 6.7 6.1 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) GCK PF07802.11 KEG11377.1 - 0.6 10.6 8.1 1.2 9.6 1.3 2.9 1 1 2 3 3 3 0 GCK domain NDUF_B7 PF05676.13 KEG11377.1 - 1.8 8.3 10.3 1.2 8.9 2.3 2.9 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zinc-ribbons_6 PF07191.12 KEG11377.1 - 2.1 8.4 6.9 5 7.2 1.4 2.3 1 1 1 2 2 2 0 zinc-ribbons Pet191_N PF10203.9 KEG11377.1 - 2.3 8.6 10.8 12 6.3 0.2 2.9 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KEG11377.1 - 5.9 7.3 7.6 3.2 8.2 1.8 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KEG11377.1 - 6.5 6.8 11.4 4.8 7.3 5.3 2.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like MORN PF02493.20 KEG11378.1 - 5.3e-31 104.7 51.0 0.00015 21.4 2.9 10.2 10 1 0 10 10 10 9 MORN repeat PH PF00169.29 KEG11378.1 - 2.3e-07 31.3 0.0 3.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KEG11378.1 - 0.019 15.4 0.0 0.07 13.6 0.0 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain DUF3048_C PF17479.2 KEG11378.1 - 0.63 10.4 3.9 0.74 10.2 0.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Tropomyosin PF00261.20 KEG11379.1 - 1.7e-05 24.3 25.6 0.0014 18.1 2.6 3.4 2 1 1 3 3 3 2 Tropomyosin GAS PF13851.6 KEG11379.1 - 3.1e-05 23.4 12.7 3.1e-05 23.4 12.7 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 KEG11379.1 - 0.00057 19.4 11.5 0.00057 19.4 11.5 2.4 2 1 1 3 3 3 1 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 KEG11379.1 - 0.0036 17.5 27.7 0.22 11.7 3.1 3.8 2 1 1 3 3 3 3 Tropomyosin like GIT_CC PF16559.5 KEG11379.1 - 0.0077 16.1 12.5 0.44 10.5 1.0 3.9 3 1 0 3 3 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KEG11379.1 - 0.0083 16.3 20.9 0.12 12.5 0.4 4.2 2 1 2 4 4 4 2 Centrosomin N-terminal motif 1 Lectin_N PF03954.14 KEG11379.1 - 0.009 15.8 12.5 0.15 11.8 0.2 3.4 2 1 1 3 3 3 2 Hepatic lectin, N-terminal domain KLRAQ PF10205.9 KEG11379.1 - 0.0097 16.1 18.2 0.014 15.6 2.0 3.7 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein DUF2935 PF11155.8 KEG11379.1 - 0.01 16.1 0.0 1.2 9.5 0.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ADIP PF11559.8 KEG11379.1 - 0.02 15.0 24.4 1.1 9.3 2.0 3.3 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 KEG11379.1 - 0.024 14.9 25.9 0.31 11.2 2.6 3.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 MT PF12777.7 KEG11379.1 - 0.03 13.4 0.6 0.03 13.4 0.6 2.2 3 0 0 3 3 3 0 Microtubule-binding stalk of dynein motor DUF4226 PF10774.9 KEG11379.1 - 0.036 14.4 2.8 0.036 14.4 2.8 3.5 3 1 2 5 5 4 0 Domain of unknown function (DUF4226) DUF1465 PF07323.12 KEG11379.1 - 0.043 13.7 16.7 0.29 11.0 2.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) YabA PF06156.13 KEG11379.1 - 0.065 13.9 1.4 0.065 13.9 1.4 3.7 2 1 2 4 4 4 0 Initiation control protein YabA CEP63 PF17045.5 KEG11379.1 - 0.098 12.5 17.5 0.076 12.9 2.7 3.1 3 0 0 3 3 3 0 Centrosomal protein of 63 kDa Cep57_CLD_2 PF14197.6 KEG11379.1 - 0.13 12.3 23.9 1.1 9.3 1.8 4.4 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF948 PF06103.11 KEG11379.1 - 0.26 11.6 7.4 25 5.2 0.1 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 KEG11379.1 - 0.3 9.7 13.3 0.093 11.4 4.3 2.2 2 0 0 2 2 2 0 AAA domain DUF641 PF04859.12 KEG11379.1 - 0.32 11.3 15.1 0.48 10.8 1.2 3.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) WD40_alt PF14077.6 KEG11379.1 - 0.36 10.7 7.9 4.8 7.1 0.1 4.4 4 1 1 5 5 5 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.12 KEG11379.1 - 0.38 10.8 31.2 0.19 11.8 6.5 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 KEG11379.1 - 0.45 10.5 26.4 2.3 8.2 2.0 3.1 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion HAP1_N PF04849.13 KEG11379.1 - 0.47 9.6 25.8 9 5.4 25.8 2.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Fez1 PF06818.15 KEG11379.1 - 0.52 10.7 21.8 0.11 12.9 1.9 3.0 1 1 2 3 3 3 0 Fez1 FlxA PF14282.6 KEG11379.1 - 0.73 9.8 21.5 0.068 13.2 1.2 4.1 2 2 1 3 3 3 0 FlxA-like protein JAKMIP_CC3 PF16034.5 KEG11379.1 - 1.1 9.1 21.1 2.6 8.0 10.5 2.6 1 1 1 2 2 2 0 JAKMIP CC3 domain DASH_Spc19 PF08287.11 KEG11379.1 - 1.2 9.1 26.8 0.96 9.3 10.8 2.8 3 0 0 3 3 3 0 Spc19 KIAA1430 PF13879.6 KEG11379.1 - 1.6 9.5 10.1 2 9.2 1.6 2.9 3 1 0 3 3 2 0 KIAA1430 homologue CEND1 PF15677.5 KEG11379.1 - 2 9.0 9.7 0.081 13.5 2.0 2.3 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 DUF4407 PF14362.6 KEG11379.1 - 2.1 7.6 23.4 1.2e+02 1.9 23.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 KEG11379.1 - 2.2 8.6 21.9 1.7 8.9 0.9 4.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 KEG11379.1 - 2.3 9.2 22.7 5.5 7.9 2.8 3.8 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 KEG11379.1 - 2.3 8.0 15.1 4 7.2 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Spectrin PF00435.21 KEG11379.1 - 2.3 8.7 21.5 3.2 8.3 1.7 3.8 2 1 2 4 4 4 0 Spectrin repeat DUF3450 PF11932.8 KEG11379.1 - 2.5 7.3 24.6 3.2 7.0 4.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DLP_helical PF18709.1 KEG11379.1 - 2.9 7.0 13.4 0.83 8.8 6.9 2.5 2 1 0 2 2 2 0 Dynamin-like helical domain IFP_35_N PF07334.13 KEG11379.1 - 3.5 7.7 19.1 3.5 7.8 0.9 4.9 3 2 2 5 5 5 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus CENP-H PF05837.12 KEG11379.1 - 3.7 8.0 28.9 4.2 7.8 6.4 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) HIP1_clath_bdg PF16515.5 KEG11379.1 - 4.2 8.1 24.8 0.19 12.3 2.8 3.5 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KEG11379.1 - 5.5 5.8 25.9 0.38 9.6 13.5 2.5 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF4763 PF15960.5 KEG11379.1 - 6 6.1 21.8 1.6 8.0 4.4 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4763) SHE3 PF17078.5 KEG11379.1 - 6.8 6.3 12.6 0.67 9.6 0.3 3.0 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 MscS_porin PF12795.7 KEG11379.1 - 7.7 6.0 34.2 0.072 12.6 4.9 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Fungal_TACC PF12709.7 KEG11379.1 - 9 6.8 12.9 16 6.0 0.2 4.0 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins UPF0242 PF06785.11 KEG11379.1 - 9.7 6.2 23.4 13 5.8 1.8 3.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 KEG11380.1 - 0.0027 17.8 4.1 0.0027 17.8 4.1 13.0 8 4 5 13 13 13 2 TolA binding protein trimerisation Atg14 PF10186.9 KEG11380.1 - 0.0053 15.9 16.3 0.0053 15.9 16.3 7.3 2 1 6 8 8 8 2 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 KEG11380.1 - 0.0075 16.1 2.0 0.0075 16.1 2.0 10.2 5 1 5 11 11 11 3 Phage minor structural protein GP20 KASH_CCD PF14662.6 KEG11380.1 - 0.015 15.1 1.2 0.015 15.1 1.2 9.2 3 3 7 10 10 10 0 Coiled-coil region of CCDC155 or KASH CDP-OH_P_transf PF01066.21 KEG11381.1 - 7.8e-12 45.8 2.0 7.8e-12 45.8 2.0 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Stc1 PF12898.7 KEG11382.1 - 0.00016 22.1 3.4 0.004 17.7 0.5 2.6 1 1 1 2 2 2 1 Stc1 domain zf-piccolo PF05715.13 KEG11382.1 - 0.0028 17.8 3.8 0.0062 16.7 3.8 1.7 1 1 0 1 1 1 1 Piccolo Zn-finger zinc_ribbon_12 PF11331.8 KEG11382.1 - 0.029 14.2 0.5 0.029 14.2 0.5 2.5 2 1 0 3 3 3 0 Probable zinc-ribbon domain Mu-like_Com PF10122.9 KEG11382.1 - 0.13 11.8 0.4 0.13 11.8 0.4 3.1 2 1 0 2 2 2 0 Mu-like prophage protein Com RNHCP PF12647.7 KEG11382.1 - 1.3 9.0 8.1 0.72 9.9 4.2 2.2 1 1 1 2 2 2 0 RNHCP domain Opiods_neuropep PF01160.18 KEG11382.1 - 1.5 9.0 8.6 2.2 8.5 3.7 2.5 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide zf-B_box PF00643.24 KEG11382.1 - 7.8 6.7 12.1 47 4.2 0.0 3.4 2 1 1 3 3 3 0 B-box zinc finger P4Ha_N PF08336.11 KEG11384.1 - 0.037 14.0 0.7 0.037 14.0 0.7 1.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Plant_NMP1 PF06694.11 KEG11384.1 - 0.064 12.3 0.4 0.1 11.7 0.4 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) DUF2681 PF10883.8 KEG11384.1 - 0.16 12.4 3.7 0.32 11.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) LcrG PF07216.12 KEG11384.1 - 1.3 9.0 9.0 1.1 9.2 6.1 2.2 1 1 1 2 2 2 0 LcrG protein FUSC PF04632.12 KEG11384.1 - 5.1 5.5 12.7 6.2 5.2 12.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 KEG11385.1 - 8e-60 202.4 0.0 1.1e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11385.1 - 2.6e-35 122.0 0.0 3.5e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11385.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEG11385.1 - 0.0049 16.5 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KEG11385.1 - 0.0078 15.0 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG11385.1 - 0.018 14.9 2.9 0.043 13.7 2.9 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KEG11385.1 - 0.028 13.8 0.1 0.05 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family JAB PF01398.21 KEG11386.1 - 1e-19 70.7 0.0 2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KEG11386.1 - 9.7e-09 35.0 2.0 4.2e-08 33.0 2.0 2.0 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Lzipper-MIP1 PF14389.6 KEG11386.1 - 0.032 14.5 1.8 0.047 14.0 0.8 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 BTB PF00651.31 KEG11387.1 - 1.3e-10 41.4 0.1 0.0001 22.5 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 KEG11387.1 - 0.014 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 MATH domain ZZ PF00569.17 KEG11387.1 - 0.4 10.5 2.4 6.7 6.6 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type Cep57_MT_bd PF06657.13 KEG11389.1 - 0.00042 20.7 2.4 0.00042 20.7 2.4 4.7 3 1 1 4 4 4 1 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 KEG11389.1 - 0.00055 19.4 23.4 0.0021 17.4 17.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Cep57_CLD PF14073.6 KEG11389.1 - 0.001 19.1 32.7 0.001 19.1 32.7 2.4 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 DUF4795 PF16043.5 KEG11389.1 - 0.013 15.1 28.7 0.021 14.4 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) NOG1_N PF17835.1 KEG11389.1 - 0.014 15.3 0.6 0.014 15.3 0.6 2.7 2 1 0 2 2 2 0 NOG1 N-terminal helical domain Exonuc_VII_L PF02601.15 KEG11389.1 - 0.044 13.4 21.7 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit IFT57 PF10498.9 KEG11389.1 - 0.12 11.3 26.3 0.073 12.0 15.6 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF812 PF05667.11 KEG11389.1 - 0.6 8.9 30.3 0.94 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.11 KEG11389.1 - 1.2 9.4 39.9 0.53 10.5 1.4 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CAP_N PF01213.19 KEG11389.1 - 2 7.9 13.2 4.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ARL2_Bind_BART PF11527.8 KEG11389.1 - 2 8.5 12.0 2.7 8.1 0.2 2.9 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART CENP-F_leu_zip PF10473.9 KEG11389.1 - 2.1 8.4 43.5 0.072 13.1 23.2 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 KEG11389.1 - 5.1 6.8 48.7 3.8 7.2 15.1 3.1 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 KEG11389.1 - 5.2 7.1 12.6 2.2 8.3 0.9 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KEG11389.1 - 7.1 7.0 37.4 1.7 9.1 1.2 2.8 2 1 2 4 4 4 0 Fez1 Ntox1 PF15500.6 KEG11389.1 - 9 6.7 16.8 8.6 6.8 5.6 3.4 2 1 1 3 3 3 0 Putative RNase-like toxin, toxin_1 STAG PF08514.11 KEG11391.1 - 2e-20 72.8 0.0 7.4e-20 71.0 0.0 2.0 1 0 0 1 1 1 1 STAG domain NDUF_B4 PF07225.12 KEG11391.1 - 0.12 12.3 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Proteasome PF00227.26 KEG11393.1 - 5e-53 179.4 0.0 6.2e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG11393.1 - 1.3e-13 50.4 0.1 3e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF848 PF05852.11 KEG11393.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Clathrin PF00637.20 KEG11394.1 - 4.1e-162 532.5 33.3 3.1e-29 101.7 0.3 8.3 8 0 0 8 8 8 8 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KEG11394.1 - 5.5e-17 61.4 0.2 9.3e-16 57.5 0.0 3.0 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 KEG11394.1 - 7.9e-12 44.3 0.1 3.9e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.20 KEG11394.1 - 1.9e-08 34.2 0.0 0.083 13.2 0.0 4.3 4 0 0 4 4 4 2 Clathrin propeller repeat ELYS PF13934.6 KEG11394.1 - 0.0026 17.8 1.7 1.3 9.0 0.2 3.9 3 0 0 3 3 3 1 Nuclear pore complex assembly TPR_7 PF13176.6 KEG11394.1 - 0.007 16.3 0.6 6.6 7.0 0.0 5.6 6 1 1 7 7 6 1 Tetratricopeptide repeat Vps39_2 PF10367.9 KEG11394.1 - 0.057 13.9 0.2 12 6.4 0.1 3.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 ATP13 PF12921.7 KEG11394.1 - 0.086 12.7 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression TPR_14 PF13428.6 KEG11394.1 - 0.088 13.7 21.6 0.55 11.2 0.4 8.7 8 2 1 9 9 8 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KEG11394.1 - 0.09 11.8 8.2 0.025 13.6 0.6 3.5 5 0 0 5 5 5 0 Coatomer WD associated region TPR_1 PF00515.28 KEG11394.1 - 0.18 11.7 9.4 5.5 7.0 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG11394.1 - 0.38 11.0 7.1 1.7e+02 2.7 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.8 KEG11395.1 - 1.8 8.6 11.8 0.033 14.2 3.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GlutR_dimer PF00745.20 KEG11395.1 - 2.1 8.9 7.9 0.44 11.0 2.3 2.7 1 1 2 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3552 PF12072.8 KEG11396.1 - 0.0054 16.2 21.4 0.0081 15.6 21.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) V_ATPase_I PF01496.19 KEG11396.1 - 0.06 11.3 9.1 0.074 11.0 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KEG11396.1 - 0.061 12.9 12.0 0.092 12.3 12.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 KEG11396.1 - 0.17 10.5 13.4 0.21 10.1 13.4 1.1 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 KEG11396.1 - 0.3 9.5 13.3 0.45 8.9 13.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hydin_ADK PF17213.3 KEG11396.1 - 0.62 10.3 10.3 1.3 9.2 10.3 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 KEG11396.1 - 0.67 10.4 15.7 0.96 9.9 15.7 1.2 1 0 0 1 1 1 0 AAA domain DUF775 PF05603.12 KEG11396.1 - 4.4 6.8 11.3 8.1 5.9 8.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) FPP PF05911.11 KEG11396.1 - 4.7 5.3 19.5 6.4 4.8 19.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 KEG11396.1 - 4.9 6.1 17.8 8.6 5.3 17.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4834 PF16118.5 KEG11396.1 - 5.3 8.1 8.0 13 6.8 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NAP PF00956.18 KEG11396.1 - 5.6 6.1 12.9 9.2 5.4 12.9 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) ALMT PF11744.8 KEG11396.1 - 7.5 5.3 7.3 10 4.8 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Het-C PF07217.11 KEG11396.1 - 8.1 4.8 9.2 11 4.4 9.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C LMBR1 PF04791.16 KEG11396.1 - 9.6 5.0 7.2 13 4.6 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Serinc PF03348.15 KEG11397.1 - 2.9e-57 194.5 30.6 3.1e-56 191.1 30.6 1.9 1 1 0 1 1 1 1 Serine incorporator (Serinc) YadA_head PF05658.14 KEG11397.1 - 0.68 10.4 2.9 1.6 9.2 2.9 1.7 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin EF-hand_6 PF13405.6 KEG11398.1 - 6.6e-11 41.2 9.1 0.024 14.6 0.1 6.9 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 KEG11398.1 - 4.4e-06 27.0 3.4 10 6.6 0.0 6.0 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_11 PF08976.11 KEG11398.1 - 1.6e-05 25.7 0.8 0.46 11.4 0.0 4.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 KEG11398.1 - 6.7e-05 22.7 0.2 0.17 11.8 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG11398.1 - 0.001 18.4 3.8 1.9 8.3 0.1 5.4 7 0 0 7 7 7 1 EF hand Frankia_peptide PF14407.6 KEG11398.1 - 0.015 15.3 0.9 1.2 9.1 0.0 4.4 5 0 0 5 5 5 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PrgI PF12666.7 KEG11399.1 - 0.24 12.2 1.9 4.2 8.1 1.9 2.2 1 1 0 1 1 1 0 PrgI family protein SNF2_N PF00176.23 KEG11400.1 - 4e-14 52.1 0.0 1.8e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG11400.1 - 5.3e-08 33.2 0.0 1.6e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FHA PF00498.26 KEG11400.1 - 2.2e-07 31.1 0.0 5.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain ERCC3_RAD25_C PF16203.5 KEG11400.1 - 0.014 14.7 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEG11400.1 - 0.029 14.4 0.0 0.21 11.6 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit COX6B PF02297.17 KEG11401.1 - 0.019 15.2 1.8 0.019 15.2 1.8 2.8 1 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KEG11401.1 - 0.099 12.7 6.2 5.2 7.2 0.1 3.1 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KEG11401.1 - 0.22 11.9 5.4 6.6 7.1 1.2 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KEG11401.1 - 0.59 10.3 3.3 25 5.1 0.4 3.2 2 1 0 2 2 2 0 CHCH domain COX17 PF05051.13 KEG11401.1 - 0.73 10.2 5.6 17 5.9 0.1 3.2 4 0 0 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KEG11401.1 - 1.3 9.3 11.8 12 6.2 0.7 3.9 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KEG11401.1 - 9.6 6.5 8.6 3.7 7.8 0.5 3.0 1 1 2 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein TLD PF07534.16 KEG11402.1 - 2.1e-22 79.9 0.0 4.5e-21 75.5 0.1 2.4 2 1 0 2 2 2 1 TLD Apolipoprotein PF01442.18 KEG11403.1 - 4.8e-06 26.6 5.7 4.8e-06 26.6 5.7 2.3 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KEG11403.1 - 0.014 15.4 2.7 1.3 9.0 0.0 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 KEG11403.1 - 0.032 14.3 7.2 0.2 11.7 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) GAS PF13851.6 KEG11403.1 - 0.079 12.3 11.0 0.028 13.8 4.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Sipho_Gp157 PF05565.11 KEG11403.1 - 0.17 11.9 10.0 1.3 9.0 1.7 3.3 2 1 1 4 4 4 0 Siphovirus Gp157 DUF4600 PF15372.6 KEG11403.1 - 0.46 10.9 5.2 6.8 7.1 0.8 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4600) Allexi_40kDa PF05549.11 KEG11403.1 - 0.72 9.3 5.6 7.8 5.9 1.5 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein Jnk-SapK_ap_N PF09744.9 KEG11403.1 - 1.1 9.4 12.3 0.16 12.2 2.8 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.8 KEG11403.1 - 1.3 8.4 9.1 0.35 10.3 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 KEG11403.1 - 2.5 8.2 6.0 6.1 6.9 0.4 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 KEG11403.1 - 3.8 8.0 10.0 8.3 6.9 0.0 3.6 2 2 2 4 4 4 0 Spectrin repeat Clathrin PF00637.20 KEG11404.1 - 4.5e-11 42.8 0.0 2.5e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS F-box PF00646.33 KEG11404.1 - 2.2e-06 27.4 0.1 3.6e-05 23.5 0.0 2.9 2 0 0 2 2 2 1 F-box domain LIM PF00412.22 KEG11404.1 - 0.017 15.3 2.4 0.017 15.3 2.4 3.6 5 0 0 5 5 5 0 LIM domain F-box-like PF12937.7 KEG11404.1 - 0.071 13.0 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 F-box-like SPATA9 PF15824.5 KEG11405.1 - 0.0002 20.8 0.2 0.00026 20.4 0.2 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated protein 9 NPV_P10 PF05531.12 KEG11405.1 - 0.00028 21.3 2.2 0.48 10.9 0.0 2.4 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 KEG11405.1 - 0.00086 19.2 0.2 0.0014 18.5 0.2 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain PriC PF07445.12 KEG11405.1 - 0.0021 18.0 0.7 0.0028 17.6 0.7 1.3 1 0 0 1 1 1 1 Primosomal replication protein priC EzrA PF06160.12 KEG11405.1 - 0.0066 14.7 0.3 0.0078 14.4 0.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 KEG11405.1 - 0.013 15.6 1.3 0.062 13.3 0.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KEG11405.1 - 0.015 15.4 0.6 0.024 14.7 0.6 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF148 PF02520.17 KEG11405.1 - 0.025 14.7 0.4 0.048 13.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Bacillus_HBL PF05791.11 KEG11405.1 - 0.028 14.3 2.6 1.4 8.7 0.3 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) WXG100 PF06013.12 KEG11405.1 - 0.031 14.5 0.3 0.069 13.4 0.3 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 KEG11405.1 - 0.043 13.9 1.4 0.28 11.2 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Utp12 PF04003.12 KEG11405.1 - 0.73 10.2 4.3 20 5.5 0.9 2.8 1 1 1 2 2 2 0 Dip2/Utp12 Family PMM PF03332.13 KEG11406.1 - 2.4e-100 334.9 1.4 2.7e-100 334.7 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KEG11406.1 - 4.3e-08 33.2 0.0 2.8e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEG11406.1 - 0.001 18.7 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KEG11406.1 - 0.031 14.5 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEG11406.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.6 KEG11407.1 - 6.6e-05 23.2 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KEG11407.1 - 0.041 14.4 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 KEG11408.1 - 2.7e-26 93.4 0.0 3.8e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RIX1 PF08167.12 KEG11409.1 - 0.22 11.3 4.5 8.6 6.0 0.1 3.8 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis SDA1 PF05285.12 KEG11409.1 - 0.98 8.8 4.9 1.5 8.1 4.9 1.2 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 KEG11409.1 - 7.5 7.0 11.9 3.2e+02 1.8 0.0 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Spc7 PF08317.11 KEG11410.1 - 0.0022 16.9 10.5 0.0022 16.9 10.5 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein DASH_Duo1 PF08651.10 KEG11410.1 - 0.64 9.8 6.8 5 7.0 0.3 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF1993 PF09351.10 KEG11410.1 - 1.7 8.7 10.0 0.47 10.6 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) LMBR1 PF04791.16 KEG11410.1 - 1.9 7.3 7.9 2.5 6.9 7.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Golgin_A5 PF09787.9 KEG11410.1 - 7.1 6.0 33.2 0.38 10.2 11.8 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 KIAA1430 PF13879.6 KEG11411.1 - 2.1e-19 70.2 5.0 4.1e-19 69.2 5.0 1.5 1 0 0 1 1 1 1 KIAA1430 homologue Aa_trans PF01490.18 KEG11412.1 - 3.1e-49 167.8 35.6 4e-49 167.4 35.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PHO4 PF01384.20 KEG11413.1 - 2.8e-114 381.7 13.4 3.3e-114 381.4 13.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family DOT1 PF08123.13 KEG11415.1 - 2.7e-22 79.3 0.0 3.5e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KEG11415.1 - 2.5e-05 24.1 0.0 4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG11415.1 - 4.9e-05 24.0 0.0 8.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG11415.1 - 5.8e-05 23.7 0.1 0.00012 22.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEG11415.1 - 0.00031 20.7 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KEG11415.1 - 0.015 15.7 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 KEG11415.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KEG11415.1 - 0.025 14.0 0.0 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KEG11415.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KEG11415.1 - 0.055 14.2 0.0 0.094 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4268 PF14088.6 KEG11415.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) MetW PF07021.12 KEG11415.1 - 0.079 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 KEG11415.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 KEG11415.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Sulfotransfer_3 PF13469.6 KEG11415.1 - 0.18 12.2 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family WD40 PF00400.32 KEG11416.1 - 6.1e-12 45.9 7.7 0.00032 21.5 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat VPS9 PF02204.18 KEG11417.1 - 2.4e-05 24.5 0.1 4.4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RNA_pol_Rpb2_6 PF00562.28 KEG11418.1 - 2.8e-116 388.8 0.0 4.5e-116 388.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEG11418.1 - 8.9e-44 149.4 0.3 1.3e-43 148.9 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KEG11418.1 - 4.7e-31 107.0 0.4 4.1e-30 104.0 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KEG11418.1 - 1e-20 73.7 1.8 1e-20 73.7 1.8 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 KEG11418.1 - 8.5e-20 71.2 0.8 3.2e-19 69.3 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KEG11418.1 - 5.6e-19 68.1 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KEG11418.1 - 4.7e-08 33.5 1.2 1.4e-07 32.0 1.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Glyco_tranf_2_3 PF13641.6 KEG11420.1 - 1.7e-07 31.3 0.0 3.9e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEG11420.1 - 4.6e-07 29.8 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KEG11420.1 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 eIF-5a PF01287.20 KEG11425.1 - 1.1e-25 89.5 0.2 1.8e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KEG11425.1 - 1.1e-05 25.4 0.1 2.5e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain SNF2_N PF00176.23 KEG11426.1 - 1.2e-56 191.9 0.0 1.6e-29 102.7 0.0 3.3 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG11426.1 - 2.2e-17 63.4 0.0 4.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KEG11426.1 - 1.3e-08 35.0 4.2 1.3e-08 35.0 4.2 3.3 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 KEG11426.1 - 2.1e-05 24.3 4.5 2.1e-05 24.3 4.5 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG11426.1 - 3.8e-05 23.4 4.9 3.8e-05 23.4 4.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KEG11426.1 - 6.8e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 KEG11426.1 - 0.00013 21.9 4.0 0.00013 21.9 4.0 2.3 3 0 0 3 3 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KEG11426.1 - 0.00044 20.5 3.5 0.00044 20.5 3.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEG11426.1 - 0.00062 19.5 1.1 0.0017 18.0 1.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KEG11426.1 - 0.0014 18.7 5.1 0.0018 18.3 1.7 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KEG11426.1 - 0.0032 17.4 4.7 0.0032 17.4 4.7 3.3 4 0 0 4 4 3 1 zinc-RING finger domain PHD PF00628.29 KEG11426.1 - 0.0058 16.5 2.4 0.0058 16.5 2.4 3.0 3 0 0 3 3 2 1 PHD-finger Zf_RING PF16744.5 KEG11426.1 - 0.0078 16.3 0.4 0.023 14.8 0.4 1.8 1 0 0 1 1 1 1 KIAA1045 RING finger Prok-RING_4 PF14447.6 KEG11426.1 - 0.015 15.1 4.9 0.015 15.1 4.9 3.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 CpXC PF14353.6 KEG11426.1 - 0.017 15.1 0.6 3.9 7.5 0.0 3.5 3 0 0 3 3 3 0 CpXC protein FYDLN_acid PF09538.10 KEG11426.1 - 0.036 14.8 0.1 0.036 14.8 0.1 3.4 3 1 0 3 3 2 0 Protein of unknown function (FYDLN_acid) RINGv PF12906.7 KEG11426.1 - 0.097 12.8 2.0 0.28 11.3 2.0 1.9 1 0 0 1 1 1 0 RING-variant domain zinc-ribbons_6 PF07191.12 KEG11426.1 - 0.52 10.3 8.0 1 9.4 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbons FANCL_C PF11793.8 KEG11426.1 - 2.5 8.3 6.4 3.7 7.8 0.8 3.2 3 0 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KEG11426.1 - 3.5 7.9 15.7 0.098 12.8 5.8 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KEG11426.1 - 5.1 7.0 13.4 4 7.3 2.7 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 KEG11426.1 - 9.7 6.2 7.6 27 4.8 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain PP2C PF00481.21 KEG11427.1 - 1.7e-53 181.9 0.3 2.5e-53 181.3 0.3 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Skp1 PF01466.19 KEG11428.1 - 0.05 13.7 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Skp1 family, dimerisation domain PABP PF00658.18 KEG11428.1 - 0.2 11.9 0.7 0.56 10.4 0.4 1.8 1 1 0 1 1 1 0 Poly-adenylate binding protein, unique domain Cyclin_N PF00134.23 KEG11429.1 - 4.5e-10 39.4 0.0 7.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 KEG11430.1 - 7.8e-45 153.3 0.1 2.1e-22 79.8 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11430.1 - 4e-16 59.1 0.1 4.8e-08 32.6 0.2 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG11430.1 - 0.0041 16.5 0.0 0.45 9.8 0.0 2.7 3 0 0 3 3 3 1 Kinase-like MecA PF05389.12 KEG11430.1 - 0.0049 16.5 0.2 0.93 9.1 0.1 2.2 2 0 0 2 2 2 2 Negative regulator of genetic competence (MecA) Pkinase_fungal PF17667.1 KEG11430.1 - 0.0098 14.7 0.7 0.013 14.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KEG11430.1 - 0.025 13.9 0.4 0.048 13.0 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RseA_C PF03873.13 KEG11430.1 - 0.22 11.8 17.0 1.4 9.2 0.7 3.5 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain FlgM PF04316.13 KEG11430.1 - 4.2 7.8 7.4 6.9 7.1 0.6 3.5 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM SAPIS-gp6 PF16722.5 KEG11430.1 - 6.7 7.2 7.9 20 5.7 0.3 2.5 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Prefoldin_2 PF01920.20 KEG11431.1 - 1.4e-11 44.3 2.6 1.7e-11 44.0 2.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PHY PF00360.20 KEG11431.1 - 0.0087 15.4 0.1 0.01 15.2 0.1 1.1 1 0 0 1 1 1 1 Phytochrome region KfrA_N PF11740.8 KEG11431.1 - 0.014 16.0 6.2 0.018 15.7 6.2 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Sel1 PF08238.12 KEG11431.1 - 0.057 14.1 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Sel1 repeat Prefoldin PF02996.17 KEG11431.1 - 0.31 10.9 8.6 0.64 10.0 3.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit TPR_2 PF07719.17 KEG11432.1 - 0.00056 19.8 3.1 0.072 13.2 1.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11432.1 - 0.0051 16.9 1.1 0.12 12.6 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG11432.1 - 0.025 14.4 0.7 0.061 13.2 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG11432.1 - 0.25 11.6 4.1 0.55 10.6 4.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG11432.1 - 2.1 9.4 4.3 6.1 7.9 2.7 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat PIP5K PF01504.18 KEG11433.1 - 9.9e-70 234.9 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 KEG11434.1 - 5.8e-25 88.2 0.0 6.4e-15 55.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11434.1 - 8.7e-11 41.6 0.0 5.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UDPG_MGDP_dh_N PF03721.14 KEG11435.1 - 2e-50 171.0 0.0 3.6e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KEG11435.1 - 3.6e-36 123.7 0.0 4.5e-35 120.3 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KEG11435.1 - 6.4e-30 103.2 0.1 2.1e-29 101.6 0.0 1.9 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 KEG11435.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain VRR_NUC PF08774.11 KEG11436.1 - 8.7e-15 54.7 0.0 2.6e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Mur_ligase_M PF08245.12 KEG11437.1 - 8.9e-09 35.6 0.0 2.3e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain RCC1_2 PF13540.6 KEG11438.1 - 1.9e-21 75.3 8.9 3.9e-08 32.9 0.0 4.0 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KEG11438.1 - 1.4e-17 64.0 13.1 1.9e-05 25.2 2.7 5.4 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat ZapB PF06005.12 KEG11439.1 - 0.48 10.9 6.4 0.27 11.7 1.6 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Terminase_4 PF05119.12 KEG11439.1 - 0.65 10.5 5.2 19 5.8 1.6 3.0 2 1 0 2 2 2 0 Phage terminase, small subunit Proteasome PF00227.26 KEG11441.1 - 4.7e-32 111.0 0.0 5.5e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 KEG11442.1 - 6.7e-57 193.2 0.0 1.7e-56 191.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KEG11442.1 - 8.6e-43 146.9 2.0 1.9e-42 145.7 2.0 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 KEG11442.1 - 2.5e-27 95.2 0.4 2.5e-27 95.2 0.4 2.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 KEG11442.1 - 9.5e-12 45.1 0.0 1.2e-10 41.5 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) FATC PF02260.20 KEG11442.1 - 1.6e-09 37.4 0.3 4.9e-09 35.9 0.3 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KEG11442.1 - 1.2e-06 28.2 2.4 16 6.1 0.0 7.0 5 0 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KEG11442.1 - 0.049 14.2 0.0 1.1 10.0 0.0 3.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KEG11442.1 - 0.089 13.3 0.5 9.6 6.8 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat PagP PF07017.11 KEG11443.1 - 0.044 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Rcd1 PF04078.13 KEG11444.1 - 3.9e-102 341.0 0.2 4.5e-102 340.8 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like WAPL PF07814.13 KEG11444.1 - 0.1 11.4 0.4 0.17 10.7 0.2 1.4 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin RRM_1 PF00076.22 KEG11445.1 - 1e-29 102.1 0.0 1.9e-13 50.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG11445.1 - 3.2e-06 27.2 0.0 0.053 13.6 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 KEG11445.1 - 1.7e-05 24.8 0.0 0.0021 18.0 0.0 2.9 3 0 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.6 KEG11445.1 - 5.2e-05 23.2 0.0 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KEG11445.1 - 0.0003 20.8 0.0 0.12 12.5 0.1 2.5 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM PF05172.13 KEG11445.1 - 0.0022 17.9 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 KEG11445.1 - 0.075 12.9 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 KEG11445.1 - 0.4 10.9 3.3 18 5.5 0.3 3.4 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Oxidored_q3 PF00499.20 KEG11446.1 - 0.0053 16.5 11.1 0.0053 16.5 11.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 FixQ PF05545.11 KEG11446.1 - 3.3 7.8 19.4 5.9 7.0 1.2 3.4 3 1 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ YqhR PF11085.8 KEG11446.1 - 8.1 6.3 14.4 2 8.3 8.7 1.9 1 1 1 2 2 2 0 Conserved membrane protein YqhR WD40 PF00400.32 KEG11447.1 - 1.2e-07 32.3 5.5 0.00027 21.7 0.0 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG11447.1 - 4.9e-06 26.8 0.0 0.066 13.5 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG11447.1 - 0.00015 20.8 0.0 0.074 12.0 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEG11447.1 - 0.035 14.0 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Myb_DNA-bind_4 PF13837.6 KEG11448.1 - 0.011 16.1 1.9 0.36 11.2 0.1 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KEG11448.1 - 0.018 16.0 0.2 0.079 14.0 0.1 2.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain ARD PF03079.14 KEG11449.1 - 5.7e-27 94.8 0.5 5.7e-27 94.8 0.5 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.11 KEG11449.1 - 4.3e-05 23.2 0.0 7.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEG11449.1 - 0.00031 20.7 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain RET_CLD1 PF17756.1 KEG11449.1 - 0.072 13.4 0.0 1.1 9.6 0.0 2.5 1 1 0 2 2 2 0 RET Cadherin like domain 1 Hce2 PF14856.6 KEG11449.1 - 0.077 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor PhyH PF05721.13 KEG11449.1 - 0.13 12.5 0.9 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) eIF3_subunit PF08597.10 KEG11449.1 - 0.15 11.9 11.2 0.27 11.1 11.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 KEG11449.1 - 0.31 9.3 8.0 0.34 9.2 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KEG11449.1 - 0.73 8.5 2.7 0.74 8.5 2.7 1.2 1 0 0 1 1 1 0 Presenilin cNMP_binding PF00027.29 KEG11452.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Macoilin PF09726.9 KEG11454.1 - 9.4 4.7 7.4 12 4.3 7.4 1.2 1 0 0 1 1 1 0 Macoilin family IF4E PF01652.18 KEG11456.1 - 8e-50 168.7 0.2 7.1e-49 165.7 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3682 PF12446.8 KEG11456.1 - 0.0012 19.3 10.0 0.0012 19.3 10.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3682) WD40 PF00400.32 KEG11457.1 - 2.7e-06 28.0 7.8 0.033 15.1 0.3 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 KEG11457.1 - 0.18 11.7 0.0 33 4.3 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BRO1 PF03097.18 KEG11458.1 - 9.8e-54 182.6 0.2 4.3e-53 180.5 0.0 2.1 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KEG11458.1 - 8.6e-32 110.6 4.4 8.6e-32 110.6 4.4 2.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF948 PF06103.11 KEG11458.1 - 0.078 13.2 4.6 0.085 13.1 0.5 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Helicase_IV_N PF12462.8 KEG11459.1 - 0.028 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal TPR_MLP1_2 PF07926.12 KEG11460.1 - 0.12 12.5 3.2 0.25 11.4 3.2 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KEG11460.1 - 0.32 10.3 3.7 0.57 9.5 3.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 KEG11460.1 - 0.93 9.3 4.3 1 9.2 2.8 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4200 PF13863.6 KEG11460.1 - 5.3 7.5 6.0 9.6 6.6 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ABC_tran PF00005.27 KEG11461.1 - 1.8e-05 25.3 0.1 3.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KEG11461.1 - 8.1e-05 22.1 20.1 0.00016 21.1 20.1 1.5 1 0 0 1 1 1 1 ABC-2 type transporter G6PD_C PF02781.16 KEG11462.1 - 1.1e-105 353.0 0.0 1.4e-105 352.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KEG11462.1 - 5e-56 190.1 0.0 8.1e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain peroxidase PF00141.23 KEG11463.1 - 9.1e-44 149.9 0.0 1.9e-43 148.8 0.0 1.5 1 1 0 1 1 1 1 Peroxidase CLPTM1 PF05602.12 KEG11466.1 - 1.6e-97 327.3 0.4 2.7e-97 326.5 0.4 1.3 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) FUSC_2 PF13515.6 KEG11466.1 - 1.7 8.7 6.6 4 7.6 4.3 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein-like DnaJ PF00226.31 KEG11467.1 - 2.1e-13 50.2 0.0 4.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 KEG11467.1 - 0.041 12.8 0.6 11 4.8 0.0 2.9 3 0 0 3 3 3 0 Major Facilitator Superfamily PP_M1 PF03012.14 KEG11467.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoprotein 7tm_1 PF00001.21 KEG11467.1 - 0.06 12.7 0.1 0.56 9.5 0.0 2.5 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 KEG11468.1 - 1.5e-41 142.5 0.0 2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11468.1 - 3.2e-23 82.3 0.0 3.9e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11468.1 - 8.6e-05 22.0 0.0 0.00081 18.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like TNFR_c6 PF00020.18 KEG11469.1 - 0.11 12.9 5.3 3 8.3 5.3 2.5 1 1 0 1 1 1 0 TNFR/NGFR cysteine-rich region Rsm22 PF09243.10 KEG11472.1 - 2.6e-28 99.1 2.3 8.4e-17 61.3 0.4 3.3 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 KEG11472.1 - 0.018 15.7 0.0 0.87 10.3 0.0 3.0 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.22 KEG11473.1 - 2.7e-07 30.5 0.1 4.6e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF98 PF01947.16 KEG11474.1 - 0.18 11.7 0.0 24 4.9 0.0 2.3 1 1 1 2 2 2 0 p-hydroxybenzoic acid synthase Aminotran_1_2 PF00155.21 KEG11475.1 - 2.8e-72 243.9 0.0 3.2e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SET PF00856.28 KEG11479.1 - 2.8e-06 27.8 1.1 8.3e-06 26.3 1.1 1.8 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KEG11479.1 - 4.3e-05 23.3 0.0 0.33 11.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG11479.1 - 0.00052 19.6 0.0 0.071 12.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KEG11479.1 - 0.0006 20.0 0.1 0.023 14.9 0.1 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG11479.1 - 0.00083 20.0 0.4 0.11 13.4 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG11479.1 - 0.0039 17.0 0.0 0.63 10.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11479.1 - 0.16 12.3 0.0 34 5.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Actin PF00022.19 KEG11480.1 - 6.3e-87 291.8 0.0 6e-86 288.6 0.0 1.9 1 1 0 1 1 1 1 Actin Herpes_capsid PF06112.11 KEG11481.1 - 0.46 10.5 7.9 0.93 9.5 7.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AAA_16 PF13191.6 KEG11482.1 - 5.1e-05 23.7 0.8 7e-05 23.3 0.8 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEG11482.1 - 0.0014 18.9 0.1 0.1 12.9 0.1 2.1 1 1 0 2 2 2 1 AAA domain DTHCT PF08070.11 KEG11482.1 - 0.031 15.0 1.7 0.048 14.4 1.7 1.2 1 0 0 1 1 1 0 DTHCT (NUC029) region Viral_helicase1 PF01443.18 KEG11482.1 - 0.032 14.0 0.3 0.051 13.3 0.2 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KEG11482.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CDK2AP PF09806.9 KEG11482.1 - 0.83 9.7 7.4 1.2 9.1 7.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3557 PF12078.8 KEG11485.1 - 0.059 13.3 0.0 4.8 7.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3557) Arf PF00025.21 KEG11486.1 - 1.5e-21 76.6 0.8 8.1e-07 28.7 0.0 4.7 5 0 0 5 5 5 4 ADP-ribosylation factor family G-alpha PF00503.20 KEG11486.1 - 7.1e-07 28.7 0.2 0.004 16.4 0.3 2.9 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KEG11486.1 - 0.0015 18.0 0.1 0.063 12.7 0.1 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KEG11486.1 - 0.0024 18.1 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KEG11486.1 - 0.0032 17.1 0.0 1.8 8.0 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KEG11486.1 - 0.016 15.5 0.8 0.027 14.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain Selenoprotein_S PF06936.11 KEG11490.1 - 0.69 9.7 3.9 1.8 8.4 3.9 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) Acetyltransf_7 PF13508.7 KEG11493.1 - 0.0015 18.9 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEG11493.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Phos_pyr_kin PF08543.12 KEG11494.1 - 1.2e-13 51.0 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KEG11494.1 - 3.4e-08 33.1 0.1 3.4e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase FYVE_2 PF02318.16 KEG11495.1 - 0.0015 18.7 7.9 0.0033 17.6 7.9 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KEG11495.1 - 0.028 14.5 13.8 0.055 13.6 13.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger EF-hand_7 PF13499.6 KEG11497.1 - 1.4e-06 28.7 1.9 0.00019 21.8 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG11497.1 - 0.0017 18.1 0.0 0.009 15.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KEG11497.1 - 0.0046 16.4 0.2 0.027 14.0 0.1 2.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KEG11497.1 - 0.18 11.7 1.8 0.53 10.2 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair zf-C3HC4_3 PF13920.6 KEG11498.1 - 4.6e-07 29.6 8.8 4.6e-07 29.6 8.8 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG11498.1 - 0.0072 16.2 10.8 0.0072 16.2 10.8 3.6 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEG11498.1 - 0.011 15.6 11.3 0.011 15.6 11.3 4.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF1635 PF07795.11 KEG11498.1 - 0.32 10.8 5.2 0.58 10.0 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FOXP-CC PF16159.5 KEG11498.1 - 0.86 10.3 0.1 0.86 10.3 0.1 3.6 4 0 0 4 4 4 0 FOXP coiled-coil domain AAA_28 PF13521.6 KEG11499.1 - 7.8e-24 84.8 0.0 1.3e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KEG11499.1 - 0.0029 16.6 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KEG11499.1 - 0.0049 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KEG11499.1 - 0.032 14.8 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KEG11499.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.12 KEG11499.1 - 0.13 11.7 0.1 0.97 8.8 0.0 2.2 3 0 0 3 3 3 0 Poxvirus A32 protein LSM PF01423.22 KEG11500.1 - 4.9e-15 55.0 0.0 6e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain UCH PF00443.29 KEG11501.1 - 6.5e-36 124.1 0.0 1e-35 123.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG11501.1 - 7.2e-08 32.4 3.4 0.00011 21.9 3.4 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TMEM107 PF14995.6 KEG11502.1 - 5.3e-32 110.9 7.1 6.2e-32 110.6 7.1 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF2722 PF10846.8 KEG11503.1 - 0.025 13.5 0.2 0.038 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 KEG11503.1 - 0.16 11.6 5.7 0.27 10.8 5.7 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 KEG11503.1 - 0.56 9.0 3.3 1.1 8.0 3.3 1.4 1 0 0 1 1 1 0 Androgen receptor Questin_oxidase PF14027.6 KEG11504.1 - 0.048 13.2 0.3 0.067 12.7 0.3 1.1 1 0 0 1 1 1 0 Questin oxidase-like GARP PF16731.5 KEG11504.1 - 0.077 12.7 6.8 0.045 13.4 4.5 1.7 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Tautomerase PF01361.21 KEG11505.1 - 0.0031 17.4 0.2 0.084 12.8 0.0 2.8 2 0 0 2 2 2 1 Tautomerase enzyme GARP PF16731.5 KEG11505.1 - 0.0031 17.2 69.3 0.0066 16.2 24.6 3.1 1 1 2 3 3 3 2 Glutamic acid/alanine-rich protein of Trypanosoma LETM1 PF07766.13 KEG11505.1 - 0.27 10.5 0.1 0.27 10.5 0.1 1.9 2 1 1 3 3 3 0 LETM1-like protein CCDC71L PF15374.6 KEG11505.1 - 0.96 8.6 26.0 1.3 8.2 26.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Alanine_zipper PF11839.8 KEG11505.1 - 1.2 9.5 86.9 0.07 13.5 22.7 5.1 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Tropomyosin PF00261.20 KEG11505.1 - 2 7.7 36.3 2.5 7.4 36.3 1.1 1 0 0 1 1 1 0 Tropomyosin DUF2935 PF11155.8 KEG11505.1 - 8.1 6.8 10.1 1.5 9.2 1.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) LSM PF01423.22 KEG11507.1 - 6.5e-06 25.7 0.1 1.1e-05 25.1 0.1 1.3 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 KEG11507.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Hfq protein SUIM_assoc PF16619.5 KEG11508.1 - 0.0015 18.6 1.1 0.0015 18.6 1.1 2.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG11508.1 - 0.63 9.6 6.4 1.3 8.6 6.4 1.4 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 KEG11508.1 - 0.84 8.2 11.2 7.5 5.1 12.2 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cullin PF00888.22 KEG11509.1 - 1.1e-54 186.1 0.0 2.4e-44 152.0 0.0 3.4 3 1 0 3 3 3 3 Cullin family Cullin_Nedd8 PF10557.9 KEG11509.1 - 5.6e-18 64.7 0.0 1.2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Adeno_100 PF02438.16 KEG11509.1 - 0.04 12.1 0.0 0.063 11.4 0.0 1.2 1 0 0 1 1 1 0 Late 100kD protein SUIM_assoc PF16619.5 KEG11509.1 - 0.063 13.4 0.6 0.31 11.1 0.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Phosphoesterase PF04185.14 KEG11511.1 - 0.056 12.6 0.2 0.06 12.5 0.2 1.1 1 0 0 1 1 1 0 Phosphoesterase family Ntox10 PF15520.6 KEG11512.1 - 0.092 12.6 1.6 0.12 12.2 0.5 1.7 1 1 1 2 2 2 0 Novel toxin 10 DUF5560 PF17715.1 KEG11512.1 - 0.85 9.1 7.0 0.3 10.5 0.4 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5560) GMC_oxred_N PF00732.19 KEG11513.1 - 6.8e-17 61.8 0.0 9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEG11513.1 - 3.3e-07 30.9 0.0 7.5e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEG11513.1 - 8.2e-05 22.0 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEG11513.1 - 0.00023 20.4 0.7 0.28 10.2 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEG11513.1 - 0.00043 20.0 3.9 0.0016 18.1 3.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEG11513.1 - 0.0022 16.8 0.3 0.25 10.0 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 KEG11513.1 - 0.0026 17.1 0.9 0.034 13.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KEG11513.1 - 0.0027 16.8 0.2 0.0096 15.0 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEG11513.1 - 0.0054 16.9 0.2 0.014 15.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEG11513.1 - 0.12 12.4 0.4 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pkinase PF00069.25 KEG11514.1 - 1.1e-62 211.8 0.0 3.3e-62 210.2 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11514.1 - 2e-42 145.3 0.0 5.2e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase MIP-T3_C PF17749.1 KEG11515.1 - 6.1e-51 172.4 6.6 6.1e-51 172.4 6.6 4.3 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 KEG11515.1 - 4.4e-44 149.1 0.2 1.3e-43 147.6 0.2 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain peroxidase PF00141.23 KEG11517.1 - 5.6e-07 29.5 0.0 1.1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Peroxidase EELM2 PF15863.5 KEG11517.1 - 0.079 13.1 0.4 0.12 12.5 0.4 1.2 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain MerR-DNA-bind PF09278.11 KEG11517.1 - 0.16 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 MerR, DNA binding WD40 PF00400.32 KEG11518.1 - 0.0084 16.9 6.1 2.3 9.2 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Lectin_N PF03954.14 KEG11519.1 - 0.0025 17.5 6.9 0.4 10.4 0.2 3.3 2 1 1 3 3 3 3 Hepatic lectin, N-terminal domain DUF2564 PF10819.8 KEG11519.1 - 0.016 15.6 2.3 0.83 10.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) DUF3135 PF11333.8 KEG11519.1 - 1.2 9.4 0.1 1.2 9.4 0.1 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3135) F-box-like PF12937.7 KEG11520.1 - 4.1e-05 23.4 0.1 9.1e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEG11520.1 - 0.067 13.1 0.1 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 F-box domain DUF1610 PF07754.11 KEG11521.1 - 0.17 11.9 2.2 0.46 10.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Rubredoxin PF00301.20 KEG11521.1 - 0.47 10.5 4.8 0.55 10.3 0.5 2.7 3 0 0 3 3 3 0 Rubredoxin Zn-ribbon_8 PF09723.10 KEG11521.1 - 1.1 9.5 5.3 8.6 6.6 0.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain DUF2407 PF10302.9 KEG11522.1 - 5.7e-05 23.6 0.1 8.4e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEG11522.1 - 0.00013 22.0 0.1 0.00058 19.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PPR_2 PF13041.6 KEG11523.1 - 5.2e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.6 KEG11523.1 - 0.00045 20.2 0.0 0.00093 19.2 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KEG11523.1 - 0.0088 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KEG11523.1 - 0.01 16.0 0.0 0.038 14.2 0.0 2.1 1 0 0 1 1 1 0 PPR repeat ApbE PF02424.15 KEG11524.1 - 1.3e-49 169.0 0.0 2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 ApbE family FAD_binding_2 PF00890.24 KEG11524.1 - 3.9e-07 29.5 4.0 7.8e-07 28.5 4.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEG11524.1 - 2.5e-06 26.9 0.2 4.3e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KEG11524.1 - 1.5e-05 24.5 3.0 2.7e-05 23.7 3.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEG11524.1 - 1.7e-05 24.1 2.5 1.7e-05 24.1 2.5 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KEG11524.1 - 0.00025 20.4 1.7 0.00038 19.8 1.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEG11524.1 - 0.0016 17.2 2.1 0.0023 16.7 2.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KEG11524.1 - 0.0039 16.8 1.3 0.014 15.0 1.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEG11524.1 - 0.0067 15.7 0.5 0.0094 15.2 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEG11524.1 - 0.021 15.0 0.9 0.082 13.1 0.9 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3168 PF11367.8 KEG11524.1 - 0.038 14.2 0.9 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) Pyr_redox PF00070.27 KEG11524.1 - 0.069 13.7 1.0 0.15 12.7 1.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LcrV PF04792.12 KEG11524.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein Pyr_redox_3 PF13738.6 KEG11524.1 - 0.3 10.3 2.0 0.53 9.5 2.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 KEG11525.1 - 1.4e-09 38.4 0.0 3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain STT3 PF02516.14 KEG11526.1 - 2.9e-54 184.8 23.4 4.4e-52 177.6 23.4 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit ATP-synt_J PF04911.12 KEG11526.1 - 0.029 13.9 6.2 0.14 11.8 0.0 3.8 4 0 0 4 4 4 0 ATP synthase j chain Rdx PF10262.9 KEG11527.1 - 7e-07 29.4 0.0 7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Rdx family Njmu-R1 PF15053.6 KEG11528.1 - 0.026 13.7 0.1 0.027 13.6 0.1 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family SAP PF02037.27 KEG11528.1 - 0.11 12.3 4.0 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 SAP domain Herpes_capsid PF06112.11 KEG11529.1 - 0.66 10.0 5.8 1.3 9.0 5.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Kri1 PF05178.12 KEG11530.1 - 4.9e-20 72.0 14.8 4.9e-20 72.0 14.8 5.0 3 1 0 3 3 3 1 KRI1-like family Kri1_C PF12936.7 KEG11530.1 - 1.9e-18 66.4 0.1 1.9e-18 66.4 0.1 3.3 3 0 0 3 3 3 1 KRI1-like family C-terminal Gene66 PF02053.15 KEG11530.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Gene 66 (IR5) protein Med3 PF11593.8 KEG11531.1 - 0.1 11.8 1.4 0.16 11.1 1.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 KEG11531.1 - 3.1 6.4 6.0 10 4.7 2.2 2.4 2 0 0 2 2 2 0 Presenilin ASD2 PF08687.11 KEG11532.1 - 0.013 15.1 7.9 0.019 14.5 7.9 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DDE_Tnp_1_7 PF13843.6 KEG11532.1 - 0.059 12.7 6.8 0.086 12.1 6.8 1.1 1 0 0 1 1 1 0 Transposase IS4 DUF4407 PF14362.6 KEG11532.1 - 0.15 11.4 1.6 0.2 11.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SR-25 PF10500.9 KEG11532.1 - 0.31 10.6 24.8 0.53 9.8 24.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 KEG11532.1 - 0.38 9.8 10.0 0.66 9.1 10.0 1.4 1 0 0 1 1 1 0 SprA-related family Apt1 PF10351.9 KEG11532.1 - 0.72 8.6 9.7 0.86 8.4 9.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 KEG11532.1 - 1.5 5.9 7.6 1.8 5.6 7.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 KEG11532.1 - 2.3 6.6 5.5 2.6 6.4 5.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.8 KEG11532.1 - 2.8 7.5 13.3 1.4 8.4 9.5 2.0 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 KEG11532.1 - 8 6.2 9.0 13 5.5 9.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 KEG11532.1 - 9.1 6.0 11.7 18 5.0 11.7 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pkinase PF00069.25 KEG11533.1 - 1.1e-65 221.6 0.1 6.2e-65 219.2 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11533.1 - 5.4e-22 78.3 0.2 9.5e-21 74.2 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11533.1 - 6.1e-05 22.5 0.3 0.25 10.6 0.2 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEG11533.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG11533.1 - 0.027 13.3 0.0 0.06 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RPN7 PF10602.9 KEG11534.1 - 5.7e-49 166.2 0.7 1.1e-48 165.3 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KEG11534.1 - 4.6e-11 43.2 0.0 9.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KEG11534.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family zf-CCCH_7 PF18586.1 KEG11534.1 - 0.13 12.7 0.1 24 5.4 0.0 3.2 1 1 2 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_1 PF00076.22 KEG11535.1 - 1.7e-22 79.0 0.8 1.9e-09 37.2 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG11535.1 - 0.0029 17.2 0.1 2.8 7.6 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.11 KEG11535.1 - 2.6 6.8 8.5 5.2 5.8 8.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2871 PF11070.8 KEG11536.1 - 0.017 15.4 4.9 2.5 8.4 0.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Abdominal-A PF12407.8 KEG11536.1 - 0.72 9.5 2.7 1.8 8.2 2.7 1.6 1 0 0 1 1 1 0 Homeobox protein BCOR PF15808.5 KEG11538.1 - 0.002 18.4 0.8 0.0069 16.6 0.8 1.9 1 0 0 1 1 1 1 BCL-6 co-repressor, non-ankyrin-repeat region PKcGMP_CC PF16808.5 KEG11539.1 - 0.033 14.0 4.0 0.46 10.4 0.3 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fic PF02661.18 KEG11539.1 - 0.074 13.9 0.4 0.3 12.0 0.4 2.1 1 0 0 1 1 1 0 Fic/DOC family DUF668 PF05003.12 KEG11539.1 - 0.1 13.0 0.3 0.61 10.6 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF668) HMMR_C PF15908.5 KEG11539.1 - 0.7 10.1 9.8 1.5 9.1 0.9 3.2 4 0 0 4 4 4 0 Hyaluronan mediated motility receptor C-terminal Tho2 PF11262.8 KEG11539.1 - 3 7.0 5.1 0.42 9.8 0.5 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF641 PF04859.12 KEG11539.1 - 5 7.5 18.0 0.39 11.1 3.6 4.0 4 0 0 4 4 4 0 Plant protein of unknown function (DUF641) Sec7 PF01369.20 KEG11540.1 - 1.4e-22 80.3 0.0 2.2e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KEG11540.1 - 1.1e-19 70.9 2.5 3.2e-19 69.4 2.5 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KEG11540.1 - 0.025 14.2 0.1 0.058 13.1 0.1 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 CHDNT PF08073.12 KEG11540.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain Urb2 PF10441.9 KEG11540.1 - 0.22 11.4 2.6 1.1 9.1 0.2 2.6 2 0 0 2 2 2 0 Urb2/Npa2 family ANAPC4_WD40 PF12894.7 KEG11542.1 - 3.4e-08 33.7 0.0 1.7e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PhoQ_Sensor PF08918.10 KEG11542.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoQ Sensor SelB-wing_1 PF09105.10 KEG11543.1 - 0.045 13.7 0.1 0.045 13.7 0.1 1.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix RabGAP-TBC PF00566.18 KEG11544.1 - 9.1e-08 32.0 0.2 1e-07 31.8 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TFIIE-A_C PF11521.8 KEG11545.1 - 0.12 12.7 4.4 0.12 12.7 0.5 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha PI3K_1B_p101 PF10486.9 KEG11547.1 - 3.7 5.2 7.4 8.9 3.9 7.4 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RFC1 PF08519.12 KEG11548.1 - 3.3e-44 150.8 0.0 6.8e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KEG11548.1 - 3.6e-12 46.8 0.0 1.3e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEG11548.1 - 1.2e-10 41.6 0.0 2.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KEG11548.1 - 8e-05 22.9 0.2 0.00032 21.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG11548.1 - 0.00035 21.0 0.0 0.00099 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KEG11548.1 - 0.00035 20.6 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEG11548.1 - 0.0023 17.8 2.4 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEG11548.1 - 0.0024 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEG11548.1 - 0.003 17.6 0.0 0.0076 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 KEG11548.1 - 0.003 16.6 0.0 0.0062 15.5 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 KEG11548.1 - 0.0033 17.8 0.0 0.022 15.2 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_assoc_2 PF16193.5 KEG11548.1 - 0.009 16.3 0.5 0.028 14.7 0.1 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_33 PF13671.6 KEG11548.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG11548.1 - 0.018 15.6 0.0 0.062 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KEG11548.1 - 0.046 13.4 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KEG11548.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KEG11548.1 - 0.061 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.11 KEG11550.1 - 0.27 11.3 3.1 2.8 8.1 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Barttin PF15462.6 KEG11550.1 - 2.7 7.7 8.4 0.37 10.5 2.9 2.3 2 1 1 3 3 3 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Mnd1 PF03962.15 KEG11551.1 - 5.6e-18 65.0 0.0 1.6e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KEG11551.1 - 1.4e-13 50.7 0.0 3.7e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Leucine zipper with capping helix domain SwrA PF17423.2 KEG11551.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Swarming motility protein TBPIP PF07106.13 KEG11551.1 - 0.014 15.3 0.0 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain ABC_tran_CTD PF16326.5 KEG11551.1 - 0.017 15.4 6.3 0.042 14.1 6.3 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain FlxA PF14282.6 KEG11551.1 - 2.6 8.1 12.2 0.11 12.6 6.2 1.8 2 0 0 2 2 2 0 FlxA-like protein CRAL_TRIO PF00650.20 KEG11552.1 - 7.8e-13 48.4 0.0 2.3e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain Fzo_mitofusin PF04799.13 KEG11552.1 - 8.9 5.8 8.0 21 4.6 0.9 2.4 2 0 0 2 2 2 0 fzo-like conserved region CRAL_TRIO PF00650.20 KEG11553.1 - 2.9e-12 46.6 0.0 5.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.18 KEG11554.1 - 1.9e-47 161.9 32.9 2.3e-47 161.6 32.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG11554.1 - 2e-07 30.4 19.4 4.1e-07 29.4 19.4 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 KEG11555.1 - 1.1e-52 179.1 31.2 1.4e-52 178.8 31.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG11555.1 - 1.6e-09 37.3 13.7 1.6e-09 37.3 13.7 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Peptidase_C2 PF00648.21 KEG11557.1 - 1.5e-48 165.4 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG11557.1 - 1.9e-20 73.2 0.0 3.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) LRR_4 PF12799.7 KEG11559.1 - 3.6e-34 116.2 1.9 0.0027 18.1 0.0 11.9 9 2 4 13 13 13 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11559.1 - 3.5e-15 55.5 12.1 0.19 11.5 0.1 8.8 8 3 1 9 9 9 8 Leucine rich repeat LRR_6 PF13516.6 KEG11559.1 - 4.6e-15 54.3 27.5 0.13 12.4 0.0 15.4 17 0 0 17 17 17 6 Leucine Rich repeat LRR_9 PF14580.6 KEG11559.1 - 0.00037 20.0 11.6 6.8 6.2 0.0 6.4 1 1 3 6 6 6 3 Leucine-rich repeat AAA_6 PF12774.7 KEG11561.1 - 3e-158 526.0 0.0 1.7e-155 517.0 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG11561.1 - 2.8e-110 369.1 10.8 2.8e-110 369.1 10.8 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KEG11561.1 - 4.5e-108 361.1 0.0 2.2e-107 358.9 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KEG11561.1 - 4.7e-91 304.7 0.0 1.2e-90 303.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KEG11561.1 - 1.6e-74 249.8 1.6 1.6e-74 249.8 1.6 2.7 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KEG11561.1 - 3.4e-74 248.3 0.0 4e-71 238.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG11561.1 - 1e-59 201.0 0.0 3.8e-59 199.2 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG11561.1 - 2.3e-42 143.8 0.0 1.1e-38 131.9 0.0 3.3 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KEG11561.1 - 3.4e-28 98.7 13.0 3.4e-28 98.7 13.0 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KEG11561.1 - 3.1e-19 69.3 1.0 2.5e-18 66.4 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KEG11561.1 - 5.6e-19 68.5 0.2 1.4e-05 25.1 0.0 5.9 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KEG11561.1 - 8.9e-14 51.5 0.1 4.5e-13 49.3 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KEG11561.1 - 3.5e-06 27.3 3.4 0.036 14.3 0.0 5.4 5 0 0 5 5 3 2 AAA domain AAA PF00004.29 KEG11561.1 - 4.7e-06 27.1 6.0 0.034 14.6 0.0 3.6 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEG11561.1 - 0.00013 22.5 0.7 0.019 15.5 0.0 4.3 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KEG11561.1 - 0.00062 20.1 0.2 3 8.3 0.0 3.7 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.6 KEG11561.1 - 0.0015 18.9 9.7 0.039 14.3 0.0 5.7 6 0 0 6 6 4 1 AAA ATPase domain AAA_33 PF13671.6 KEG11561.1 - 0.0017 18.5 0.9 1.8 8.7 0.0 4.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KEG11561.1 - 0.004 17.2 0.5 0.33 11.0 0.0 3.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEG11561.1 - 0.0072 16.1 6.7 0.37 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 KEG11561.1 - 0.008 15.3 0.1 0.051 12.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF815 PF05673.13 KEG11561.1 - 0.018 14.2 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PfUIS3 PF11567.8 KEG11561.1 - 0.026 14.9 0.4 0.21 12.0 0.0 2.8 2 0 0 2 2 1 0 Plasmodium falciparum UIS3 membrane protein NACHT PF05729.12 KEG11561.1 - 0.045 13.7 0.1 0.59 10.0 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KEG11561.1 - 0.32 11.2 0.0 0.32 11.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 KEG11561.1 - 1.2 9.5 5.2 14 6.0 0.1 4.1 3 0 0 3 3 3 0 AAA domain DASH_Duo1 PF08651.10 KEG11561.1 - 1.8 8.4 5.5 3.5 7.5 1.8 3.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 Guanylate_kin PF00625.21 KEG11561.1 - 4.8 6.8 9.1 2.6 7.7 0.0 3.9 4 0 0 4 4 4 0 Guanylate kinase Kri1 PF05178.12 KEG11562.1 - 0.071 13.7 4.2 0.16 12.6 4.2 1.5 1 0 0 1 1 1 0 KRI1-like family F_actin_bund_C PF18060.1 KEG11562.1 - 1.5 9.0 10.5 0.41 10.8 5.4 2.0 2 0 0 2 2 2 0 F actin bundling C terminal TTL PF03133.15 KEG11563.1 - 2.1e-56 191.2 0.0 3e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG11563.1 - 1.8e-07 30.7 0.0 0.0056 16.0 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KEG11563.1 - 1.5e-05 24.4 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KEG11563.1 - 0.0018 18.3 0.0 0.076 13.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KEG11563.1 - 0.013 15.1 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 KEG11563.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain WD40 PF00400.32 KEG11564.1 - 1.3e-09 38.5 0.5 2.2e-05 25.1 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG11564.1 - 0.077 13.3 0.0 9.9 6.5 0.0 2.4 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2508 PF10704.9 KEG11565.1 - 0.14 12.4 5.7 0.11 12.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Bacillus_HBL PF05791.11 KEG11565.1 - 0.18 11.7 4.8 0.99 9.2 3.8 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4367 PF14285.6 KEG11565.1 - 0.18 12.3 0.2 0.4 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Spectrin PF00435.21 KEG11565.1 - 0.44 11.1 17.5 0.83 10.2 0.2 3.4 1 1 1 3 3 3 0 Spectrin repeat DUF4407 PF14362.6 KEG11565.1 - 0.95 8.7 16.6 0.27 10.6 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MDMPI_C PF07398.11 KEG11566.1 - 2.5 9.0 8.1 0.49 11.3 1.6 3.0 3 0 0 3 3 3 0 MDMPI C-terminal domain ATP_bind_1 PF03029.17 KEG11567.1 - 4e-51 174.1 0.0 1.7e-47 162.3 0.0 2.7 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KEG11567.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEG11567.1 - 0.032 14.5 0.0 0.071 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEG11567.1 - 0.054 13.9 0.0 0.53 10.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEG11567.1 - 0.062 13.8 1.4 0.14 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEG11567.1 - 0.17 11.9 0.0 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KEG11567.1 - 0.18 12.2 1.0 0.44 11.0 0.3 2.1 2 0 0 2 2 2 0 AAA domain PAP_assoc PF03828.19 KEG11568.1 - 0.0019 18.4 0.0 0.0058 16.8 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEG11568.1 - 0.063 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.6 KEG11569.1 - 3.3e-30 101.6 35.8 0.00016 21.5 0.0 13.0 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 KEG11569.1 - 8e-05 22.9 22.7 0.75 10.3 0.1 7.1 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG11569.1 - 0.016 15.6 14.0 42 5.3 0.0 8.4 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 KEG11569.1 - 2.4 8.0 26.8 2.5 7.9 2.2 7.6 7 2 0 7 7 7 0 Leucine rich repeat Ank_2 PF12796.7 KEG11570.1 - 0.00027 21.5 0.0 0.00091 19.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2842 PF11003.8 KEG11572.1 - 0.13 12.5 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Complex1_LYR PF05347.15 KEG11573.1 - 0.0024 17.9 1.6 0.0024 17.9 1.6 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Clr5 PF14420.6 KEG11573.1 - 0.047 13.9 2.1 1.7 9.0 0.1 3.1 2 1 1 3 3 3 0 Clr5 domain eIF-5_eIF-2B PF01873.17 KEG11575.1 - 2.6e-28 98.2 1.0 4.8e-28 97.4 1.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PRR18 PF15671.5 KEG11575.1 - 0.38 10.6 10.9 0.4 10.5 8.7 2.0 1 1 1 2 2 2 0 Proline-rich protein family 18 Img2 PF05046.14 KEG11576.1 - 0.00026 21.2 0.0 0.00041 20.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) CAP_N PF01213.19 KEG11576.1 - 0.13 11.7 4.4 0.19 11.2 4.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal VIR_N PF15912.5 KEG11576.1 - 0.8 9.2 4.3 1.2 8.7 4.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal TMEM52 PF14979.6 KEG11577.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 52 OATP PF03137.20 KEG11577.1 - 0.15 10.3 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_q2 PF00420.24 KEG11578.1 - 0.041 13.5 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM52 PF14979.6 KEG11578.1 - 0.26 11.2 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane 52 SET PF00856.28 KEG11580.1 - 0.15 12.4 2.1 3.3 8.1 0.6 2.8 2 1 0 2 2 2 0 SET domain CNDH2_C PF16858.5 KEG11580.1 - 0.46 10.3 19.5 0.11 12.3 13.9 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SLC12 PF03522.15 KEG11580.1 - 0.68 8.9 14.3 0.14 11.2 10.4 1.7 2 0 0 2 2 2 0 Solute carrier family 12 CAF1 PF04857.20 KEG11580.1 - 1.4 8.0 8.0 3.1 6.9 8.0 1.5 1 0 0 1 1 1 0 CAF1 family ribonuclease Hydin_ADK PF17213.3 KEG11580.1 - 7.9 6.7 19.6 6.2 7.1 14.8 2.7 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Peptidase_M8 PF01457.16 KEG11581.1 - 1.1e-112 377.5 0.1 1.4e-112 377.1 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin APO_RNA-bind PF05634.11 KEG11581.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 APO RNA-binding NAM-associated PF14303.6 KEG11582.1 - 0.0062 17.3 7.5 0.0078 16.9 7.5 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain CDC45 PF02724.14 KEG11582.1 - 0.46 8.7 15.1 0.52 8.6 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 KEG11582.1 - 0.72 9.9 18.1 0.87 9.7 18.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein eIF3_subunit PF08597.10 KEG11582.1 - 1.2 8.9 20.8 1.6 8.6 20.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RRN3 PF05327.11 KEG11582.1 - 2 6.9 13.0 2.2 6.7 13.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_LMP1 PF05297.11 KEG11582.1 - 7.2 5.7 5.2 7.6 5.6 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Zip PF02535.22 KEG11582.1 - 8.1 5.5 5.6 9.8 5.3 5.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Mucin PF01456.17 KEG11584.1 - 0.0012 18.9 4.3 0.0012 18.9 4.3 4.1 4 1 0 4 4 4 2 Mucin-like glycoprotein Alanine_zipper PF11839.8 KEG11584.1 - 0.0015 18.8 17.7 0.0015 18.8 17.7 7.2 2 2 5 7 7 7 4 Alanine-zipper, major outer membrane lipoprotein NAD_binding_4 PF07993.12 KEG11585.1 - 0.00025 20.3 0.0 0.0068 15.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KEG11585.1 - 0.00029 20.8 2.2 0.0038 17.1 0.9 2.7 2 1 1 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 KEG11585.1 - 0.012 15.1 0.1 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEG11585.1 - 0.019 14.6 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 KEG11585.1 - 0.035 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 KEG11585.1 - 0.04 14.3 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEG11585.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF2157 PF09925.9 KEG11586.1 - 2 8.2 11.8 0.3 10.9 4.1 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Sel1 PF08238.12 KEG11587.1 - 2.7e-16 59.7 3.6 4.5e-06 27.2 0.0 3.9 4 0 0 4 4 4 3 Sel1 repeat E1-E2_ATPase PF00122.20 KEG11588.1 - 1.6e-24 86.4 0.0 5.5e-24 84.7 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEG11588.1 - 1.6e-13 51.4 5.6 1.5e-06 28.7 0.5 3.8 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEG11588.1 - 0.00015 21.8 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEG11588.1 - 0.018 14.8 0.2 0.05 13.3 0.2 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF805 PF05656.14 KEG11588.1 - 0.26 11.7 0.0 0.26 11.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF805) Dpy-30 PF05186.13 KEG11589.1 - 2.5e-13 49.5 0.0 3.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif BPL_LplA_LipB PF03099.19 KEG11590.1 - 7.2e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.26 KEG11591.1 - 5.5e-08 32.8 8.0 0.00025 21.3 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEG11591.1 - 1.6e-07 31.5 7.8 0.0043 17.8 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger SSB PF00436.25 KEG11591.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family zf-C2H2_6 PF13912.6 KEG11591.1 - 0.00018 21.4 6.2 0.019 14.9 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KEG11591.1 - 0.00019 22.1 1.2 0.12 13.0 0.0 2.9 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KEG11591.1 - 0.00072 19.9 2.7 0.38 11.1 0.1 2.6 3 0 0 3 3 2 2 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 KEG11591.1 - 0.0025 16.4 1.2 0.74 8.3 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 KEG11591.1 - 0.0025 17.4 3.4 0.12 12.1 0.2 2.5 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KEG11591.1 - 0.0082 16.4 3.2 1.2 9.5 0.4 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 KEG11591.1 - 0.018 15.5 0.9 1.2 9.6 0.1 2.7 3 0 0 3 3 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 KEG11591.1 - 0.023 13.9 0.1 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family CpXC PF14353.6 KEG11591.1 - 0.029 14.4 0.0 15 5.7 0.0 2.8 3 0 0 3 3 3 0 CpXC protein zf-met PF12874.7 KEG11591.1 - 0.046 14.1 4.1 0.086 13.3 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-met2 PF12907.7 KEG11591.1 - 0.064 13.4 1.2 0.064 13.4 1.2 2.4 2 0 0 2 2 2 0 Zinc-binding Zn-ribbon_8 PF09723.10 KEG11591.1 - 0.064 13.4 0.7 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Herpes_UL3 PF03369.13 KEG11591.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL3 protein zf-trcl PF13451.6 KEG11591.1 - 0.17 11.8 0.8 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain TFIIS_C PF01096.18 KEG11591.1 - 0.22 11.4 1.5 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.13 KEG11591.1 - 0.31 10.8 1.7 0.85 9.4 0.1 2.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-LYAR PF08790.11 KEG11591.1 - 0.39 10.7 2.6 18 5.3 0.4 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 KEG11591.1 - 0.45 10.9 4.4 0.56 10.6 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KEG11591.1 - 0.5 10.0 4.4 11 5.7 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PQQ_2 PF13360.6 KEG11592.1 - 4.8e-05 23.1 8.0 0.0025 17.4 5.6 2.9 1 1 2 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 KEG11592.1 - 8.2e-05 22.8 0.5 2.5 8.5 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4156 PF13698.6 KEG11592.1 - 0.036 14.4 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) WD40 PF00400.32 KEG11592.1 - 0.068 14.1 3.0 15 6.6 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat DNA_binding_1 PF01035.20 KEG11592.1 - 0.074 13.2 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4012 PF13196.6 KEG11592.1 - 0.095 13.2 0.6 21 5.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4012) DUF948 PF06103.11 KEG11592.1 - 3.4 8.0 6.2 46 4.4 2.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.7 KEG11592.1 - 3.8 7.7 26.8 0.094 12.9 8.1 2.4 1 1 1 2 2 2 0 Tropomyosin like FA_desaturase PF00487.24 KEG11593.1 - 4e-34 118.6 23.3 5.5e-34 118.1 23.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEG11593.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BCNT PF07572.12 KEG11594.1 - 0.17 12.0 3.3 0.37 10.9 3.3 1.6 1 0 0 1 1 1 0 Bucentaur or craniofacial development Lactococcin_972 PF09683.10 KEG11595.1 - 2.9 8.5 6.6 7.2 7.2 1.8 2.1 1 1 1 2 2 2 0 Bacteriocin (Lactococcin_972) ATP-synt_C PF00137.21 KEG11596.1 - 5.8e-09 36.2 11.8 5.8e-09 36.2 11.8 1.8 2 0 0 2 2 2 1 ATP synthase subunit C DUF2865 PF11064.8 KEG11597.1 - 0.018 15.5 0.5 0.04 14.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2865) Aminotran_5 PF00266.19 KEG11598.1 - 5.8e-67 226.2 0.0 6.4e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEG11598.1 - 1.8e-08 34.1 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEG11598.1 - 1.7e-05 24.4 0.1 2.1e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KEG11598.1 - 0.0014 17.5 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain GvpO PF05800.11 KEG11598.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO AAA PF00004.29 KEG11599.1 - 8.2e-34 116.9 0.2 1.5e-27 96.7 0.2 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG11599.1 - 3.5e-12 47.0 0.4 0.00012 22.5 0.0 3.2 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KEG11599.1 - 2.3e-11 44.1 0.1 5e-05 23.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KEG11599.1 - 2.9e-09 36.9 1.5 0.00045 20.0 0.5 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KEG11599.1 - 1.9e-08 34.4 0.1 0.0015 18.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEG11599.1 - 5.4e-08 33.4 0.0 0.033 14.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KEG11599.1 - 1.1e-07 32.1 0.0 0.0048 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KEG11599.1 - 1.6e-07 31.6 0.2 0.00043 20.4 0.1 3.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KEG11599.1 - 1.9e-07 30.7 0.1 0.0062 15.9 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_lid_3 PF17862.1 KEG11599.1 - 4.3e-07 29.6 0.2 9e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain DUF2075 PF09848.9 KEG11599.1 - 5.9e-07 29.1 0.3 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 KEG11599.1 - 9.2e-07 28.4 0.0 0.0043 16.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 KEG11599.1 - 1.5e-06 28.2 1.4 0.017 15.0 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_19 PF13245.6 KEG11599.1 - 2.6e-06 27.8 1.7 0.15 12.4 0.0 3.8 4 1 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 KEG11599.1 - 9.2e-06 26.0 0.1 0.1 13.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NB-ARC PF00931.22 KEG11599.1 - 1e-05 24.9 0.0 0.034 13.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 KEG11599.1 - 1.2e-05 25.0 1.4 0.044 13.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KEG11599.1 - 1.2e-05 25.8 0.0 0.053 14.0 0.0 3.1 3 0 0 3 3 2 1 ABC transporter TsaE PF02367.17 KEG11599.1 - 1.6e-05 24.9 0.1 0.088 12.8 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KEG11599.1 - 2.3e-05 24.2 0.2 0.079 12.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KEG11599.1 - 2.4e-05 24.1 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 KEG11599.1 - 2.9e-05 23.9 0.2 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KEG11599.1 - 4e-05 23.2 0.3 0.083 12.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEG11599.1 - 5.8e-05 22.9 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_11 PF13086.6 KEG11599.1 - 6.5e-05 22.8 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KEG11599.1 - 0.00023 20.6 0.3 0.3 10.4 0.0 2.9 2 1 0 2 2 2 2 KaiC KTI12 PF08433.10 KEG11599.1 - 0.00026 20.5 0.1 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KEG11599.1 - 0.00038 20.9 0.2 0.068 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KEG11599.1 - 0.00061 19.8 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KEG11599.1 - 0.0008 19.7 1.4 0.089 13.0 0.0 3.0 2 2 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KEG11599.1 - 0.0012 18.0 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KEG11599.1 - 0.0032 17.5 0.0 4.5 7.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KEG11599.1 - 0.0039 16.7 1.2 0.37 10.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein MeaB PF03308.16 KEG11599.1 - 0.0062 15.5 0.6 1.9 7.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PPV_E1_C PF00519.17 KEG11599.1 - 0.0064 15.4 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 1 Papillomavirus helicase TniB PF05621.11 KEG11599.1 - 0.0072 15.8 0.1 3 7.2 0.0 3.5 3 1 0 3 3 3 1 Bacterial TniB protein ResIII PF04851.15 KEG11599.1 - 0.0084 16.1 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 KEG11599.1 - 0.015 15.2 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NTPase 6PF2K PF01591.18 KEG11599.1 - 0.016 14.5 0.0 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Torsin PF06309.11 KEG11599.1 - 0.041 14.0 0.0 4 7.6 0.0 2.4 2 0 0 2 2 2 0 Torsin PIF1 PF05970.14 KEG11599.1 - 0.044 13.0 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DAP3 PF10236.9 KEG11599.1 - 0.045 12.9 0.1 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.19 KEG11599.1 - 0.051 13.2 0.8 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activ_2 PF14532.6 KEG11599.1 - 0.073 13.2 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KEG11599.1 - 0.094 12.6 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KEG11599.1 - 0.1 12.7 0.0 1.5 8.9 0.0 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 KEG11599.1 - 0.12 12.0 0.0 9.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 KEG11599.1 - 0.14 11.9 0.0 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein EBP PF05241.12 KEG11600.1 - 4.6e-13 49.0 1.2 5.5e-13 48.7 1.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 KEG11600.1 - 0.026 14.9 3.7 0.04 14.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF1616 PF07760.11 KEG11600.1 - 0.062 12.7 0.1 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) CDC27 PF09507.10 KEG11601.1 - 0.35 10.2 28.0 0.57 9.5 28.0 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 KEG11601.1 - 0.83 7.8 57.1 1.3 7.2 57.1 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KEG11601.1 - 1.4 7.4 63.0 2 6.9 63.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MRP PF09387.10 KEG11602.1 - 6e-27 94.9 0.0 9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP WGG PF10273.9 KEG11603.1 - 8.8e-07 29.5 2.7 2.1e-06 28.3 2.7 1.7 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Benyvirus_14KDa PF07255.11 KEG11603.1 - 0.0077 16.5 0.5 0.059 13.6 0.2 2.0 1 1 1 2 2 2 1 Benyvirus 14KDa protein Alliinase_C PF04864.13 KEG11603.1 - 0.037 12.9 0.1 0.05 12.5 0.1 1.1 1 0 0 1 1 1 0 Allinase SspO PF08175.12 KEG11603.1 - 0.062 13.8 4.5 0.12 12.9 4.5 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein O family TPR_1 PF00515.28 KEG11605.1 - 4.5e-22 76.9 37.8 0.00028 20.6 1.4 10.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEG11605.1 - 3.8e-20 70.3 39.5 0.002 18.1 0.8 11.8 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEG11605.1 - 1.9e-19 69.7 28.2 3.9e-07 30.3 0.7 8.5 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 KEG11605.1 - 4.2e-17 62.4 15.5 0.0002 21.8 0.0 7.1 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11605.1 - 1.6e-16 59.1 33.4 0.014 15.5 0.2 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KEG11605.1 - 1.9e-16 60.4 13.4 0.008 16.8 0.4 7.0 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEG11605.1 - 5.2e-15 54.9 8.4 0.16 12.9 0.0 9.6 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEG11605.1 - 1.7e-14 52.7 19.5 0.022 14.8 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 KEG11605.1 - 1.1e-13 50.9 24.5 0.00065 20.2 0.0 9.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG11605.1 - 2.3e-10 40.0 18.6 1.8e-05 24.3 1.8 7.2 7 1 0 7 7 7 3 TPR repeat ANAPC3 PF12895.7 KEG11605.1 - 8.4e-10 38.7 24.6 4.5e-05 23.6 0.3 5.9 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEG11605.1 - 1.6e-07 31.3 2.8 0.16 12.2 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG11605.1 - 1.5e-06 28.2 19.3 0.22 12.0 1.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat RPN7 PF10602.9 KEG11605.1 - 1.4e-05 24.8 0.9 0.064 13.0 0.0 4.4 4 1 1 5 5 5 1 26S proteasome subunit RPN7 TPR_21 PF09976.9 KEG11605.1 - 0.00099 18.9 11.7 0.0017 18.1 1.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 KEG11605.1 - 0.0011 19.4 0.9 12 6.9 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KEG11605.1 - 0.0021 18.2 13.8 3.1 8.3 0.0 7.3 8 0 0 8 8 7 2 PPR repeat Fis1_TPR_C PF14853.6 KEG11605.1 - 0.051 13.7 19.8 1.7 8.8 0.4 6.7 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KEG11605.1 - 0.066 13.1 29.0 3.1 7.8 0.3 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF4810 PF16068.5 KEG11605.1 - 0.07 13.7 3.0 6.6 7.4 0.0 4.8 6 0 0 6 6 4 0 Domain of unknown function (DUF4810) DUF3856 PF12968.7 KEG11605.1 - 0.14 12.2 3.6 1.9 8.6 0.3 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 KEG11605.1 - 2.1 8.8 4.8 18 5.7 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CW_binding_1 PF01473.20 KEG11606.1 - 0.2 12.1 1.3 0.44 11.0 1.3 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat TFIIA PF03153.13 KEG11606.1 - 5.7 6.8 25.6 8.1 6.3 25.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2380 PF09533.10 KEG11606.1 - 8.3 6.0 8.2 15 5.1 8.2 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) MFS_1 PF07690.16 KEG11607.1 - 2e-35 122.4 42.7 2.5e-19 69.5 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEG11607.1 - 1.6e-06 27.3 23.6 0.0018 17.2 6.5 2.1 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KEG11607.1 - 1.5e-05 24.1 13.2 1.5e-05 24.1 13.2 2.3 1 1 2 3 3 3 3 Sugar (and other) transporter DUF5453 PF17534.2 KEG11607.1 - 0.43 10.5 2.7 0.98 9.4 2.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5453) JmjC PF02373.22 KEG11608.1 - 3.8e-13 49.8 0.3 2.7e-11 43.9 0.3 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KEG11608.1 - 0.0018 18.1 0.0 0.042 13.6 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain 2OG-FeII_Oxy_5 PF13759.6 KEG11608.1 - 0.086 13.3 0.1 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase RAI16-like PF10257.9 KEG11609.1 - 1.5e-07 30.6 0.0 2.2e-06 26.8 0.0 2.3 1 1 1 2 2 2 1 Retinoic acid induced 16-like protein TetR_C_7 PF14246.6 KEG11609.1 - 0.076 13.0 0.2 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain eIF-1a PF01176.19 KEG11610.1 - 0.019 14.7 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 BLOC1S3 PF15753.5 KEG11610.1 - 2.7 8.1 6.3 2.7 8.1 4.9 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Ipi1_N PF12333.8 KEG11611.1 - 4.9e-05 23.9 1.5 0.0095 16.5 0.1 3.4 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation DUF2875 PF11394.8 KEG11611.1 - 0.071 12.0 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) HEAT PF02985.22 KEG11611.1 - 2.4 8.6 4.8 3.1 8.3 0.4 3.4 3 0 0 3 3 3 0 HEAT repeat Cmc1 PF08583.10 KEG11612.1 - 0.00064 19.7 4.7 0.0018 18.3 4.7 1.8 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 KEG11612.1 - 1 9.7 6.5 0.53 10.6 3.2 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) tRNA_SAD PF07973.14 KEG11613.1 - 1.1e-05 25.4 0.2 2.8e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KEG11613.1 - 0.0024 16.5 0.0 0.0032 16.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) F-box PF00646.33 KEG11614.1 - 0.00071 19.4 1.1 0.0017 18.2 1.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEG11614.1 - 0.0022 17.9 1.8 0.0062 16.4 1.8 1.8 1 0 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.19 KEG11616.1 - 7.2e-09 35.3 0.6 0.067 12.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KEG11616.1 - 0.00024 20.8 2.1 0.00084 19.0 0.9 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEG11616.1 - 0.0012 19.4 0.1 0.0029 18.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEG11616.1 - 0.0068 15.7 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEG11616.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 KEG11616.1 - 0.045 14.0 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KEG11616.1 - 0.049 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KEG11616.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KEG11616.1 - 0.17 11.7 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_16 PF10294.9 KEG11617.1 - 2.5e-08 33.9 0.0 0.00028 20.7 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KEG11617.1 - 0.00039 19.9 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KEG11617.1 - 0.16 12.7 0.1 0.4 11.4 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Amastin PF07344.11 KEG11618.1 - 1.7e-29 102.7 26.7 2e-18 66.7 12.1 2.1 2 0 0 2 2 2 2 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KEG11618.1 - 1.3e-08 34.9 22.3 5.2e-07 29.7 2.2 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family YoqO PF14037.6 KEG11618.1 - 0.14 12.7 1.9 9.9 6.7 0.3 2.7 2 0 0 2 2 2 0 YoqO-like protein DUF4293 PF14126.6 KEG11618.1 - 7.7 6.8 14.2 0.3 11.3 1.7 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4293) DGCR6 PF07324.11 KEG11620.1 - 0.031 13.9 0.6 0.39 10.3 1.5 1.9 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF1366 PF07104.11 KEG11620.1 - 0.091 12.5 2.4 0.19 11.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) PPL5 PF18168.1 KEG11622.1 - 3.3 6.9 6.7 45 3.2 0.0 2.4 2 0 0 2 2 2 0 Prim-pol family 5 Kinesin PF00225.23 KEG11623.1 - 1.9e-05 23.7 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DOT1 PF08123.13 KEG11625.1 - 4.5e-16 59.0 0.1 7e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 KEG11625.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.6 KEG11625.1 - 0.004 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG11625.1 - 0.007 17.0 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KEG11625.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEG11625.1 - 0.14 11.9 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Antimicrobial17 PF08129.11 KEG11625.1 - 0.15 12.1 0.3 13 5.9 0.0 2.8 2 1 1 3 3 3 0 Alpha/beta enterocin family WD40 PF00400.32 KEG11626.1 - 0.00024 21.8 0.2 12 7.0 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat V-ATPase_H_N PF03224.14 KEG11626.1 - 0.0097 15.2 4.9 0.023 14.0 0.1 3.1 3 1 0 3 3 3 1 V-ATPase subunit H MIB_HERC2 PF06701.13 KEG11626.1 - 0.011 15.9 0.8 0.029 14.6 0.8 1.7 1 0 0 1 1 1 0 Mib_herc2 LisH PF08513.11 KEG11626.1 - 0.026 14.5 0.0 0.085 12.9 0.0 2.0 1 0 0 1 1 1 0 LisH ANAPC4_WD40 PF12894.7 KEG11626.1 - 0.11 12.8 0.0 22 5.4 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 KEG11626.1 - 3.8 6.8 26.3 7.3 5.8 26.3 1.4 1 0 0 1 1 1 0 BUD22 DUF2721 PF11026.8 KEG11627.1 - 0.12 12.3 10.7 0.42 10.5 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Tetraspanin PF00335.20 KEG11627.1 - 0.25 11.0 1.5 0.35 10.5 1.5 1.2 1 0 0 1 1 1 0 Tetraspanin family DER1 PF04511.15 KEG11628.1 - 9.7e-29 100.7 13.4 1.1e-28 100.4 13.4 1.0 1 0 0 1 1 1 1 Der1-like family SAM_2 PF07647.17 KEG11629.1 - 3.6e-06 27.0 0.0 6.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEG11629.1 - 3.7e-06 27.3 0.0 7.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KEG11629.1 - 0.0035 17.8 0.1 0.0067 16.9 0.1 1.4 1 0 0 1 1 1 1 PH domain GSH_synthase PF03199.15 KEG11631.1 - 0.15 12.5 0.4 1.4 9.4 0.4 2.3 1 1 0 1 1 1 0 Eukaryotic glutathione synthase Pkinase PF00069.25 KEG11632.1 - 2e-47 161.8 0.0 2.5e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11632.1 - 1.4e-20 73.6 0.0 2e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KEG11632.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KEG11632.1 - 0.0078 16.2 0.0 0.059 13.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG11632.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEG11632.1 - 0.16 11.5 0.1 6.3 6.3 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase ABC_membrane_2 PF06472.15 KEG11633.1 - 3.5e-74 249.6 1.2 4.8e-74 249.2 1.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEG11633.1 - 2.8e-13 50.5 0.0 6.2e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEG11633.1 - 0.011 15.4 0.2 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region NACHT PF05729.12 KEG11633.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 KEG11633.1 - 0.059 12.8 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KEG11633.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NOG1_N PF17835.1 KEG11634.1 - 4e-53 179.7 0.3 7.9e-53 178.7 0.3 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KEG11634.1 - 1.6e-26 91.8 0.0 3.7e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KEG11634.1 - 8.9e-23 80.0 6.3 2.1e-22 78.8 6.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KEG11634.1 - 1.3e-17 63.9 0.0 2.7e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG11634.1 - 1.5e-09 37.6 0.0 3.4e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEG11634.1 - 0.0011 18.9 0.0 0.74 9.7 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KEG11634.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 KEG11634.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 KEG11634.1 - 0.047 13.7 0.1 12 5.9 0.0 2.9 1 1 1 2 2 2 0 Dynamin family COMM_domain PF07258.14 KEG11635.1 - 0.0059 16.7 0.0 2.7 8.2 0.0 2.3 2 0 0 2 2 2 2 COMM domain Pcc1 PF09341.10 KEG11636.1 - 1.6e-13 50.5 0.3 2.1e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.19 KEG11637.1 - 1.1e-26 92.8 0.3 2.4e-26 91.7 0.3 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Sorting_nexin PF03700.13 KEG11637.1 - 0.022 15.3 0.4 0.039 14.5 0.4 1.4 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Ribosomal_60s PF00428.19 KEG11637.1 - 0.026 15.1 6.4 0.026 15.1 6.4 2.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein zf-RanBP PF00641.18 KEG11638.1 - 1.7e-13 49.6 97.2 2.1e-05 23.8 1.2 10.1 10 0 0 10 10 10 9 Zn-finger in Ran binding protein and others DZR PF12773.7 KEG11638.1 - 9.9e-08 31.9 82.9 0.022 14.8 10.1 7.1 3 2 4 7 7 7 7 Double zinc ribbon zf-RanBP PF00641.18 KEG11639.1 - 8e-06 25.1 18.9 0.00025 20.3 5.1 18.1 17 1 2 19 19 19 10 Zn-finger in Ran binding protein and others DZR PF12773.7 KEG11639.1 - 6.2e-05 22.9 171.2 0.29 11.2 1.9 12.2 7 2 6 13 13 13 10 Double zinc ribbon ARL2_Bind_BART PF11527.8 KEG11640.1 - 1.1e-30 106.1 0.4 2.6e-30 104.9 0.4 1.6 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART UIM PF02809.20 KEG11640.1 - 0.0011 18.8 8.0 0.1 12.6 1.3 3.4 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF4320 PF14208.6 KEG11640.1 - 0.54 10.4 2.6 20 5.3 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) MscS_porin PF12795.7 KEG11642.1 - 0.0043 16.6 20.1 0.0075 15.8 20.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain CALCOCO1 PF07888.11 KEG11642.1 - 0.0044 16.0 13.6 0.0068 15.3 13.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 KEG11642.1 - 0.01 15.2 11.3 0.016 14.6 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 KEG11642.1 - 0.012 15.4 10.2 0.021 14.6 10.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 KEG11642.1 - 0.043 14.4 16.2 0.11 13.1 16.2 1.8 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_HK97_TLTM PF06120.11 KEG11642.1 - 0.049 12.8 4.1 0.1 11.8 4.1 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 KEG11642.1 - 0.064 12.8 6.0 0.11 12.0 6.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 KEG11642.1 - 0.1 11.1 6.6 0.15 10.5 6.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF3847 PF12958.7 KEG11642.1 - 0.14 12.3 13.6 0.061 13.4 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Spc7 PF08317.11 KEG11642.1 - 0.14 11.0 13.0 0.26 10.2 13.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.8 KEG11642.1 - 0.22 11.1 15.1 0.36 10.4 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3584 PF12128.8 KEG11642.1 - 0.29 8.6 14.7 0.41 8.1 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DHR10 PF18595.1 KEG11642.1 - 0.62 10.1 17.9 0.034 14.2 1.5 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF2730 PF10805.8 KEG11642.1 - 0.72 10.0 3.3 0.4 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Tropomyosin PF00261.20 KEG11642.1 - 0.78 9.1 14.1 1.5 8.2 14.1 1.4 1 0 0 1 1 1 0 Tropomyosin LMBR1 PF04791.16 KEG11642.1 - 1.3 7.8 4.6 2 7.3 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4140 PF13600.6 KEG11642.1 - 1.5 9.3 9.2 0.7 10.4 0.4 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bcr-Abl_Oligo PF09036.10 KEG11642.1 - 1.8 8.7 7.5 1.6 8.8 0.3 2.6 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain CENP-H PF05837.12 KEG11642.1 - 4.9 7.6 9.5 11 6.5 9.5 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 KEG11642.1 - 8.7 6.4 10.3 17 5.5 10.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Trypsin_2 PF13365.6 KEG11643.1 - 2.8e-06 28.3 0.0 4.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Atx10homo_assoc PF09759.9 KEG11643.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Guanylin PF02058.15 KEG11643.1 - 0.088 13.3 0.2 0.83 10.2 0.0 2.3 2 0 0 2 2 2 0 Guanylin precursor Aa_trans PF01490.18 KEG11644.1 - 4.5e-47 160.7 23.5 6.6e-47 160.1 23.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_Dp1 PF16938.5 KEG11644.1 - 0.84 9.9 4.9 1.3 9.2 0.5 3.1 3 0 0 3 3 3 0 Putative phage holin Dp-1 AAA PF00004.29 KEG11645.1 - 7.4e-96 317.6 0.0 3.8e-47 160.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG11645.1 - 1.9e-26 91.6 6.4 1.4e-12 47.2 0.2 3.0 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 KEG11645.1 - 3.4e-20 72.0 0.1 1e-19 70.5 0.1 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KEG11645.1 - 6e-14 52.1 0.0 7.3e-06 25.8 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEG11645.1 - 3.5e-12 47.0 0.2 0.00067 20.1 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KEG11645.1 - 3.6e-11 43.4 0.0 1.8e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KEG11645.1 - 4.4e-11 43.2 0.0 5.9e-06 26.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KEG11645.1 - 2.6e-10 40.4 0.4 7.7e-05 22.7 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 KEG11645.1 - 5.8e-09 35.6 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KEG11645.1 - 9.2e-09 35.7 0.3 0.037 14.3 0.0 3.9 2 2 2 4 4 3 2 AAA domain TIP49 PF06068.13 KEG11645.1 - 1.9e-08 33.9 0.0 0.00064 19.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KEG11645.1 - 9.8e-08 32.6 0.0 0.016 15.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KEG11645.1 - 1.9e-07 31.2 0.0 0.0079 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KEG11645.1 - 3.7e-07 30.5 0.0 0.0068 16.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KEG11645.1 - 4.5e-07 29.5 0.2 0.03 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEG11645.1 - 2.1e-06 27.6 0.0 0.07 12.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KEG11645.1 - 2.2e-06 27.5 0.1 0.00043 20.2 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 KEG11645.1 - 1.4e-05 25.6 0.0 0.046 14.2 0.0 3.2 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 KEG11645.1 - 1.6e-05 25.4 0.0 0.095 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEG11645.1 - 1.9e-05 24.9 0.0 0.24 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KEG11645.1 - 2e-05 24.0 0.0 0.1 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Parvo_NS1 PF01057.17 KEG11645.1 - 3.9e-05 22.9 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KEG11645.1 - 4.5e-05 23.2 0.0 0.11 12.1 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KEG11645.1 - 4.7e-05 23.1 3.5 1.9 8.0 0.1 4.2 2 2 2 4 4 4 1 AAA domain AAA_24 PF13479.6 KEG11645.1 - 4.9e-05 23.2 0.0 0.088 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KEG11645.1 - 6e-05 23.1 0.1 0.44 10.4 0.0 2.8 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea NACHT PF05729.12 KEG11645.1 - 7e-05 22.8 0.1 0.21 11.5 0.0 3.0 3 1 0 3 3 3 2 NACHT domain Bac_DnaA PF00308.18 KEG11645.1 - 7e-05 22.8 0.0 0.087 12.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 KEG11645.1 - 0.00011 22.2 0.0 0.67 10.0 0.0 2.7 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KEG11645.1 - 0.00012 21.5 0.9 1.6 8.0 0.0 3.7 4 0 0 4 4 4 1 KaiC Viral_helicase1 PF01443.18 KEG11645.1 - 0.00014 21.7 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KEG11645.1 - 0.00026 20.5 0.0 0.52 9.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 KEG11645.1 - 0.00084 19.2 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KEG11645.1 - 0.00086 18.6 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.15 KEG11645.1 - 0.00097 19.1 1.3 10 6.0 0.0 4.2 3 1 1 4 4 4 0 NTPase ResIII PF04851.15 KEG11645.1 - 0.0018 18.3 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KEG11645.1 - 0.0019 17.7 0.1 1.5 8.3 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 KEG11645.1 - 0.0032 16.7 0.0 0.88 8.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KEG11645.1 - 0.0034 17.5 0.0 1.8 8.7 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Rad17 PF03215.15 KEG11645.1 - 0.014 15.3 0.0 2 8.3 0.0 2.7 2 1 0 2 2 2 0 Rad17 P-loop domain Molydop_binding PF01568.21 KEG11645.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF815 PF05673.13 KEG11645.1 - 0.033 13.4 0.0 5 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 KEG11645.1 - 0.038 13.7 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 KEG11645.1 - 0.054 13.3 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KEG11645.1 - 0.057 13.2 0.1 5.9 6.6 0.0 3.3 4 0 0 4 4 4 0 DEAD/DEAH box helicase AAA_29 PF13555.6 KEG11645.1 - 0.058 13.2 0.0 7.3 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEG11645.1 - 0.068 13.7 0.1 21 5.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEG11645.1 - 0.07 13.5 2.9 9.4 6.6 0.1 3.3 3 1 0 4 4 2 0 AAA domain SKI PF01202.22 KEG11645.1 - 0.073 13.2 0.1 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.16 KEG11645.1 - 0.11 11.4 0.0 8 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_30 PF13604.6 KEG11645.1 - 0.12 12.1 0.1 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torus PF16131.5 KEG11646.1 - 3.4e-05 24.5 3.1 0.14 12.9 0.1 2.8 3 0 0 3 3 3 2 Torus domain zf-CCCH PF00642.24 KEG11646.1 - 0.034 14.0 1.6 0.9 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG11646.1 - 0.48 10.6 2.4 0.78 9.9 0.1 2.5 2 0 0 2 2 2 0 Zinc finger domain cNMP_binding PF00027.29 KEG11647.1 - 7.5e-21 74.0 0.0 1.1e-14 54.3 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain C2 PF00168.30 KEG11647.1 - 7.2e-16 58.4 0.0 0.00064 20.0 0.0 5.0 5 0 0 5 5 5 4 C2 domain Arf PF00025.21 KEG11648.1 - 1.3e-28 99.6 0.0 2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KEG11648.1 - 3.1e-10 39.8 0.0 6.5e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 KEG11648.1 - 1.1e-07 32.0 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEG11648.1 - 2.3e-07 30.9 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KEG11648.1 - 3e-07 30.0 0.0 4.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KEG11648.1 - 3.8e-07 29.8 0.0 5.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KEG11648.1 - 0.0013 18.3 0.7 0.026 14.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF5582 PF17819.1 KEG11648.1 - 0.029 14.8 0.3 0.061 13.8 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5582) FeoB_N PF02421.18 KEG11648.1 - 0.075 12.6 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KEG11648.1 - 0.087 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Tfb2 PF03849.14 KEG11650.1 - 3.3e-28 98.7 0.0 4.3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 KEG11650.1 - 0.0002 21.5 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cation_efflux PF01545.21 KEG11652.1 - 4.7e-23 82.0 0.1 7e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Cation efflux family Spt20 PF12090.8 KEG11653.1 - 0.67 9.5 14.1 0.36 10.4 10.9 2.1 2 0 0 2 2 2 0 Spt20 family TPR_2 PF07719.17 KEG11654.1 - 0.00013 21.8 0.1 0.00032 20.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG11654.1 - 0.0083 15.9 0.5 0.018 14.8 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Vps39_1 PF10366.9 KEG11655.1 - 0.2 11.9 0.1 0.35 11.2 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Pkinase PF00069.25 KEG11656.1 - 1.4e-53 181.9 0.0 2.3e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11656.1 - 3.4e-36 124.8 0.0 7.9e-36 123.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_2 PF07719.17 KEG11656.1 - 0.00023 21.0 0.1 0.00068 19.6 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Kinase-like PF14531.6 KEG11656.1 - 0.0028 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEG11656.1 - 0.0042 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family MGS PF02142.22 KEG11656.1 - 0.007 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain TPR_1 PF00515.28 KEG11656.1 - 0.012 15.4 0.4 0.03 14.2 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat FTA2 PF13095.6 KEG11656.1 - 0.15 11.6 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CbtB PF09489.10 KEG11656.1 - 8.8 6.5 7.0 1.3 9.2 0.3 2.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Fascin PF06268.13 KEG11658.1 - 1.7e-06 28.3 0.1 4.5e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Fascin domain RIC1 PF07064.13 KEG11659.1 - 1.5e-38 132.7 0.0 2.5e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KEG11659.1 - 6.5e-06 26.4 0.0 0.011 16.0 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 KEG11660.1 - 4.7e-08 32.8 1.2 1.7e-07 31.0 0.8 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain RRM_1 PF00076.22 KEG11661.1 - 3.2e-13 49.3 1.5 1.3e-05 24.9 0.4 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG11661.1 - 0.024 14.2 0.0 3.6 7.2 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3391 PF11871.8 KEG11661.1 - 0.81 10.2 4.0 0.73 10.4 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Epimerase PF01370.21 KEG11662.1 - 8e-58 195.7 0.0 1e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEG11662.1 - 2.6e-21 76.4 0.4 4.8e-21 75.5 0.0 1.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEG11662.1 - 9.9e-08 31.3 1.2 8.3e-07 28.3 1.2 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEG11662.1 - 1.5e-06 27.6 2.9 1.6e-05 24.2 0.2 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEG11662.1 - 2.9e-06 26.6 0.0 1.1e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEG11662.1 - 0.0017 17.6 0.1 0.0072 15.5 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein LRR_4 PF12799.7 KEG11663.1 - 4.1e-16 58.8 18.2 1.6e-06 28.3 0.3 4.2 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11663.1 - 3.7e-12 45.8 7.2 4.1e-08 32.8 3.1 3.7 2 2 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KEG11663.1 - 1.4e-07 31.2 0.0 0.043 13.3 0.0 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 KEG11663.1 - 2.4e-05 24.0 1.6 7.6 6.9 0.0 3.9 2 1 1 3 3 3 3 Leucine Rich repeat DUF3939 PF13075.6 KEG11663.1 - 0.01 15.9 0.1 0.092 12.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) LRR_1 PF00560.33 KEG11663.1 - 0.014 15.9 3.4 0.68 10.7 0.8 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat Pan3_PK PF18101.1 KEG11664.1 - 2.7e-39 134.3 0.4 4e-39 133.7 0.4 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain NUDIX PF00293.28 KEG11666.1 - 2e-14 53.7 0.0 2.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain EF-hand_7 PF13499.6 KEG11668.1 - 1.6e-30 105.3 0.2 2.4e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG11668.1 - 1.8e-28 95.9 5.6 9.3e-08 31.1 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KEG11668.1 - 1.9e-21 75.7 4.0 1.4e-09 37.6 0.1 3.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KEG11668.1 - 6.9e-20 69.2 2.2 4.2e-06 26.3 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEG11668.1 - 1.5e-15 55.9 4.9 6.4e-06 25.4 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KEG11668.1 - 1.2e-08 35.2 0.0 0.00038 20.7 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 KEG11668.1 - 4e-07 29.9 0.2 0.027 14.4 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KEG11668.1 - 0.0012 19.0 0.2 1.9 8.7 0.1 2.8 2 1 0 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 KEG11668.1 - 0.022 14.7 0.0 0.092 12.7 0.0 2.0 2 1 0 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 KEG11668.1 - 0.1 13.5 0.0 10 7.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.25 KEG11669.1 - 2.9e-58 197.3 0.0 7.3e-58 196.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11669.1 - 2.3e-34 118.8 0.0 8.6e-34 117.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 KEG11669.1 - 0.0001 22.3 0.0 0.00042 20.3 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEG11669.1 - 0.00019 21.6 0.0 0.00089 19.5 0.0 2.1 2 0 0 2 2 2 1 PAS domain DUF4713 PF15831.5 KEG11669.1 - 0.0027 18.1 0.2 0.0084 16.5 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4713) Pkinase_fungal PF17667.1 KEG11669.1 - 0.0058 15.5 0.0 0.017 13.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KEG11669.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KEG11669.1 - 0.048 13.2 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 KEG11669.1 - 0.05 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KEG11669.1 - 0.077 12.3 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like PAS_4 PF08448.10 KEG11669.1 - 0.079 13.2 0.1 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 PAS fold DUF5309 PF17236.2 KEG11671.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5309) AAA_22 PF13401.6 KEG11672.1 - 0.074 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KEG11672.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 KEG11672.1 - 0.15 11.4 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Clp1 PF06807.14 KEG11673.1 - 1.6e-07 31.8 0.1 1.9e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DUF498 PF04430.14 KEG11674.1 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) tRNA_int_endo PF01974.17 KEG11675.1 - 5.4e-15 55.2 0.0 9.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.18 KEG11676.1 - 9.4e-14 51.5 1.4 1.2e-13 51.1 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Paralemmin PF03285.15 KEG11677.1 - 0.015 14.9 6.6 0.015 14.9 6.6 1.9 2 0 0 2 2 2 0 Paralemmin ECM11 PF15463.6 KEG11677.1 - 0.087 13.4 0.4 0.087 13.4 0.4 2.9 2 1 0 2 2 2 0 Extracellular mutant protein 11 DUF948 PF06103.11 KEG11677.1 - 0.24 11.7 16.2 0.23 11.7 2.1 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) H-kinase_dim PF02895.14 KEG11677.1 - 0.26 11.7 8.9 2.6 8.5 3.4 3.3 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF3450 PF11932.8 KEG11677.1 - 0.42 9.9 14.2 0.65 9.3 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_HK97_TLTM PF06120.11 KEG11677.1 - 0.56 9.3 12.4 1.6 7.9 12.3 1.6 1 1 1 2 2 2 0 Tail length tape measure protein Laminin_II PF06009.12 KEG11677.1 - 1 9.4 12.7 0.18 11.8 3.2 2.9 1 1 2 3 3 3 0 Laminin Domain II DUF1415 PF07209.12 KEG11677.1 - 1.2 8.9 6.8 6.8 6.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) KLRAQ PF10205.9 KEG11677.1 - 1.4 9.2 11.2 2.4 8.4 5.3 2.6 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Tweety PF04906.13 KEG11677.1 - 2.3 6.8 11.3 0.044 12.5 1.0 2.0 1 1 1 2 2 2 0 Tweety Syntaxin-6_N PF09177.11 KEG11677.1 - 2.9 8.5 10.7 3.6 8.2 3.6 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal APG6_N PF17675.1 KEG11677.1 - 4.5 7.8 23.4 9.1 6.8 1.5 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 KEG11677.1 - 5 5.6 14.7 4 5.9 1.4 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 KEG11677.1 - 5.9 7.4 6.8 46 4.5 0.1 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) PI3_PI4_kinase PF00454.27 KEG11678.1 - 3e-34 118.9 0.0 9.1e-24 84.6 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KEG11678.1 - 0.0055 16.1 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) CENP-F_C_Rb_bdg PF10490.9 KEG11681.1 - 0.001 18.5 0.2 0.0017 17.7 0.2 1.4 1 0 0 1 1 1 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.7 KEG11683.1 - 4e-23 81.8 0.5 4.8e-10 39.9 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG11683.1 - 1e-20 73.8 1.1 1.2e-08 35.3 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG11683.1 - 1.4e-20 71.2 0.9 0.00022 21.4 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KEG11683.1 - 4.7e-20 71.1 2.9 0.00069 20.0 0.5 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KEG11683.1 - 4.2e-16 58.8 2.5 1e-05 25.7 0.2 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PDCD2_C PF04194.13 KEG11684.1 - 3.8e-23 82.4 0.4 3.8e-23 82.4 0.4 2.4 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain tRNA-Thr_ED PF08915.11 KEG11684.1 - 0.15 12.1 0.2 0.3 11.1 0.2 1.4 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase PhnA_Zn_Ribbon PF08274.12 KEG11684.1 - 3.8 7.6 6.7 28 4.8 0.0 3.2 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 KEG11684.1 - 4.2 7.6 7.6 5.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KEG11684.1 - 4.6 7.3 14.8 0.45 10.5 1.9 3.4 2 2 2 4 4 4 0 Transposase zinc-ribbon domain LicD PF04991.13 KEG11685.1 - 4.9e-09 36.7 0.1 3.9e-05 23.9 0.2 2.1 1 1 0 2 2 2 2 LicD family Aminoglyc_resit PF10706.9 KEG11685.1 - 0.1 12.3 0.4 0.65 9.7 0.0 2.2 2 1 1 3 3 3 0 Aminoglycoside-2''-adenylyltransferase MFS_5 PF05631.14 KEG11688.1 - 9.8e-108 360.2 6.5 1.6e-107 359.5 6.5 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KEG11688.1 - 2.1e-20 73.0 28.4 4.2e-20 72.0 28.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3306 PF11748.8 KEG11689.1 - 1.4 9.8 11.2 0.12 13.2 2.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3306) zf-UBP PF02148.19 KEG11690.1 - 3.3e-09 36.9 15.7 9.5e-09 35.5 15.7 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KEG11690.1 - 3.9e-08 33.5 8.6 3.9e-08 33.5 8.6 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KEG11690.1 - 8.7e-07 28.6 6.9 8.7e-07 28.6 6.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KEG11690.1 - 2.1e-06 27.9 3.7 1e-05 25.7 3.7 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEG11690.1 - 1e-05 25.4 7.7 1e-05 25.4 7.7 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEG11690.1 - 1.9e-05 24.4 9.1 7.3e-05 22.5 9.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG11690.1 - 0.0024 17.9 4.9 0.0024 17.9 4.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG11690.1 - 0.0095 15.8 9.4 0.0095 15.8 9.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Med9 PF07544.13 KEG11690.1 - 0.61 10.2 3.9 1.1 9.4 3.9 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Ribosomal_S7e PF01251.18 KEG11691.1 - 1.7e-61 207.2 1.5 2e-61 207.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DNA_pol_B_thumb PF14791.6 KEG11692.1 - 6e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb PRIMA1 PF16101.5 KEG11692.1 - 7.7 6.6 7.2 15 5.7 7.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UTP15_C PF09384.10 KEG11693.1 - 0.013 15.2 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 UTP15 C terminal KIP1 PF07765.12 KEG11693.1 - 0.067 13.3 3.3 0.18 12.0 0.3 3.0 2 1 0 2 2 2 0 KIP1-like protein Dymeclin PF09742.9 KEG11694.1 - 5.9e-57 193.5 0.1 6.8e-57 193.3 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KEG11694.1 - 0.023 12.8 2.2 0.52 8.4 0.2 2.5 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein TMEM208_SND2 PF05620.11 KEG11695.1 - 8.1e-32 110.3 0.0 9.1e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF5373 PF17343.2 KEG11695.1 - 0.098 12.5 0.1 0.098 12.5 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Prominin PF05478.11 KEG11698.1 - 0.002 16.2 1.2 0.0037 15.3 1.2 1.3 1 0 0 1 1 1 1 Prominin DUF1664 PF07889.12 KEG11698.1 - 0.056 13.5 3.9 0.06 13.4 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1451 PF07295.11 KEG11698.1 - 0.14 12.2 11.1 1.9 8.6 2.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain Fib_alpha PF08702.10 KEG11698.1 - 0.34 11.1 4.0 0.17 12.1 0.4 2.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family SPX PF03105.19 KEG11698.1 - 0.38 10.6 8.3 0.52 10.2 8.3 1.1 1 0 0 1 1 1 0 SPX domain OmpH PF03938.14 KEG11698.1 - 0.97 9.8 10.7 0.66 10.3 0.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.11 KEG11698.1 - 3.5 7.7 7.0 10 6.2 7.0 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FliT PF05400.13 KEG11698.1 - 6.2 7.7 14.4 2 9.3 9.7 2.7 2 1 1 3 3 3 0 Flagellar protein FliT SlyX PF04102.12 KEG11698.1 - 7 7.4 7.5 0.62 10.7 1.2 2.5 2 1 0 2 2 2 0 SlyX DUF4404 PF14357.6 KEG11698.1 - 7.9 7.2 9.8 0.29 11.8 1.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) MPC PF03650.13 KEG11700.1 - 1.9e-14 53.7 0.1 2e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers YqbF PF14553.6 KEG11701.1 - 0.03 14.2 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 YqbF, hypothetical protein domain DUF378 PF04070.12 KEG11701.1 - 1.3 8.9 5.9 12 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF378) WD40 PF00400.32 KEG11702.1 - 2.3e-09 37.7 6.9 0.0051 17.6 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF5595 PF18077.1 KEG11703.1 - 0.0071 16.4 0.0 2.7 8.1 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5595) Elf1 PF05129.13 KEG11704.1 - 3.2e-16 59.1 0.6 5.1e-16 58.5 0.6 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 KEG11704.1 - 0.0084 15.5 0.4 0.017 14.5 0.4 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cys_rich_CPXG PF14255.6 KEG11704.1 - 0.023 14.6 1.1 0.048 13.6 1.1 1.6 1 0 0 1 1 1 0 Cysteine-rich CPXCG Ribosomal_60s PF00428.19 KEG11704.1 - 0.21 12.2 9.1 0.42 11.2 9.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fer4_10 PF13237.6 KEG11704.1 - 1.2 9.4 5.1 0.38 10.9 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain zinc_ribbon_5 PF13719.6 KEG11704.1 - 1.3 8.8 4.5 1.3 8.9 3.1 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Herpes_capsid PF06112.11 KEG11704.1 - 5.3 7.1 6.7 14 5.7 0.1 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Fer4_8 PF13183.6 KEG11704.1 - 7.2 7.1 8.7 1.2 9.6 2.0 2.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain Elf1 PF05129.13 KEG11705.1 - 8.1e-18 64.3 0.0 1.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 KEG11705.1 - 0.042 13.8 1.1 0.12 12.3 1.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 KEG11705.1 - 0.93 9.6 2.8 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DEAD PF00270.29 KEG11706.1 - 2.9e-33 115.1 0.1 3e-16 59.7 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG11706.1 - 4.2e-17 62.5 0.0 1.1e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG11706.1 - 5.9e-08 32.9 0.0 5e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEG11706.1 - 0.003 17.8 0.9 0.14 12.5 0.5 3.2 2 1 0 2 2 2 1 AAA domain DNA_pol_phi PF04931.13 KEG11706.1 - 6.3 4.8 10.0 0.12 10.4 2.9 1.7 2 0 0 2 2 2 0 DNA polymerase phi DUF4834 PF16118.5 KEG11706.1 - 6.9 7.7 7.6 0.65 11.0 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TruD PF01142.18 KEG11708.1 - 2.6e-19 69.3 0.0 3.2e-17 62.5 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DLEU7 PF15760.5 KEG11709.1 - 0.57 9.6 4.7 0.56 9.7 3.1 1.8 2 0 0 2 2 2 0 Leukemia-associated protein 7 SCO1-SenC PF02630.14 KEG11710.1 - 2.3e-31 108.5 0.1 1.5e-29 102.6 0.1 2.2 1 1 0 1 1 1 1 SCO1/SenC GRAM PF02893.20 KEG11711.1 - 0.0075 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 GRAM domain AAA PF00004.29 KEG11712.1 - 3e-51 173.3 0.0 1.9e-35 122.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG11712.1 - 5.5e-10 38.9 0.0 1.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 KEG11712.1 - 4.3e-09 37.0 0.0 0.0014 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KEG11712.1 - 1.1e-08 35.1 0.0 0.00069 19.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG11712.1 - 1.2e-08 35.4 1.3 0.048 13.9 0.6 4.4 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 KEG11712.1 - 2.2e-07 30.4 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 KEG11712.1 - 3.4e-07 30.8 0.3 0.094 13.1 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KEG11712.1 - 8.4e-06 26.0 0.0 0.042 14.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KEG11712.1 - 5.4e-05 22.7 0.1 0.0055 16.1 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KEG11712.1 - 0.0001 22.7 0.2 0.023 15.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KEG11712.1 - 0.0002 21.2 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KEG11712.1 - 0.0006 19.6 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KEG11712.1 - 0.00062 20.1 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KEG11712.1 - 0.00076 19.3 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KEG11712.1 - 0.00077 19.0 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KEG11712.1 - 0.00098 19.1 0.1 2.9 7.8 0.1 3.3 2 1 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.26 KEG11712.1 - 0.001 18.8 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 KEG11712.1 - 0.0015 18.7 0.0 0.01 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) KTI12 PF08433.10 KEG11712.1 - 0.0015 18.0 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 KEG11712.1 - 0.002 17.4 0.3 0.56 9.4 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 KEG11712.1 - 0.0034 17.5 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 KEG11712.1 - 0.0036 17.1 0.1 1.7 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain CDC48_N PF02359.18 KEG11712.1 - 0.004 17.3 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 KEG11712.1 - 0.0074 16.0 0.0 0.38 10.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KEG11712.1 - 0.011 15.1 0.1 0.47 9.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 KEG11712.1 - 0.015 15.5 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KEG11712.1 - 0.016 14.7 0.1 0.95 8.9 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 KEG11712.1 - 0.031 14.3 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KEG11712.1 - 0.033 13.5 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 KEG11712.1 - 0.041 14.2 0.5 1.7 8.9 0.2 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KEG11712.1 - 0.055 14.0 0.1 6.5 7.3 0.0 2.9 2 1 1 3 3 3 0 ABC transporter Cytidylate_kin PF02224.18 KEG11712.1 - 0.061 13.1 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 KEG11712.1 - 0.1 11.7 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.6 KEG11712.1 - 0.11 12.2 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KEG11712.1 - 0.13 11.8 3.2 6.8 6.2 0.1 3.5 4 0 0 4 4 3 0 AAA domain Thymidylate_kin PF02223.17 KEG11712.1 - 0.14 11.9 0.0 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase CDC48_2 PF02933.17 KEG11712.1 - 0.16 11.8 0.4 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 TTL PF03133.15 KEG11713.1 - 7.3e-56 189.5 0.0 1.1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG11713.1 - 0.00023 20.5 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Tubulin_3 PF14881.6 KEG11714.1 - 0.0031 17.2 0.0 0.0072 16.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KEG11714.1 - 0.0036 17.6 0.0 0.0077 16.5 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Prefoldin_2 PF01920.20 KEG11717.1 - 1e-19 70.5 3.0 1.2e-19 70.2 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 KEG11717.1 - 0.00034 21.2 1.3 0.00034 21.2 1.3 2.1 2 0 0 2 2 2 1 SlyX Zwint PF15556.6 KEG11717.1 - 0.0022 17.6 1.8 0.0022 17.6 1.8 1.7 2 0 0 2 2 2 1 ZW10 interactor betaPIX_CC PF16523.5 KEG11717.1 - 0.0093 15.8 1.8 0.066 13.0 0.1 2.1 2 0 0 2 2 2 1 betaPIX coiled coil CotJB PF12652.7 KEG11717.1 - 0.02 15.1 0.8 0.039 14.2 0.1 1.8 2 0 0 2 2 2 0 CotJB protein TPD52 PF04201.15 KEG11717.1 - 0.021 14.4 0.3 0.021 14.4 0.3 1.6 2 0 0 2 2 2 0 Tumour protein D52 family NYD-SP28_assoc PF14775.6 KEG11717.1 - 0.024 14.8 3.7 2.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain LRIF1 PF15741.5 KEG11717.1 - 0.06 11.9 0.4 0.068 11.7 0.4 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Spectrin PF00435.21 KEG11717.1 - 0.069 13.6 3.5 0.087 13.3 1.3 1.9 1 1 1 2 2 2 0 Spectrin repeat HalX PF08663.10 KEG11717.1 - 0.091 13.1 2.3 0.16 12.3 0.2 2.1 2 0 0 2 2 2 0 HalX domain RecG_N PF17190.4 KEG11717.1 - 0.13 13.0 3.2 0.24 12.2 0.4 2.1 1 1 1 2 2 2 0 RecG N-terminal helical domain DivIVA PF05103.13 KEG11717.1 - 0.15 12.1 8.6 1.8 8.7 2.2 2.2 2 0 0 2 2 2 0 DivIVA protein FTA4 PF13093.6 KEG11717.1 - 0.2 11.5 7.5 0.44 10.4 1.1 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DASH_Dad3 PF08656.10 KEG11717.1 - 0.21 11.7 3.5 1.3 9.1 0.7 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 EAP30 PF04157.16 KEG11717.1 - 0.21 10.8 4.2 0.15 11.3 0.4 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Cep57_MT_bd PF06657.13 KEG11717.1 - 0.25 11.8 3.9 0.85 10.1 0.5 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 KEG11717.1 - 0.47 11.1 4.7 11 6.7 0.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KEG11717.1 - 0.49 10.6 7.1 4.8 7.4 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KEG11717.1 - 0.6 10.2 11.2 2.3 8.3 2.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FIN1 PF17300.2 KEG11717.1 - 0.62 9.5 3.6 8.5 5.8 0.1 2.1 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 DUF2203 PF09969.9 KEG11717.1 - 0.83 10.4 4.5 2.1 9.1 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.12 KEG11717.1 - 0.85 8.1 3.1 0.93 7.9 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YafQ_toxin PF15738.5 KEG11717.1 - 1 9.7 3.5 3.5 8.0 0.3 2.1 1 1 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ CRA_rpt PF07046.11 KEG11717.1 - 1.6 8.9 5.8 9.3 6.5 0.1 2.7 3 0 0 3 3 2 0 Cytoplasmic repetitive antigen (CRA) like repeat TYW3 PF02676.14 KEG11718.1 - 1e-56 191.7 0.0 1.3e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 AAA_33 PF13671.6 KEG11719.1 - 7.3e-05 23.0 0.0 0.00021 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEG11719.1 - 0.00012 21.4 0.0 0.0018 17.6 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KEG11719.1 - 0.002 18.5 0.1 0.0046 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KEG11719.1 - 0.067 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KEG11719.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain KOG2701 PF09762.9 KEG11720.1 - 2.4e-34 119.1 6.7 2.7e-34 118.9 0.0 3.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein (DUF2037) DUF3492 PF11997.8 KEG11720.1 - 1.3 8.7 6.3 2.4 7.8 5.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) Pet191_N PF10203.9 KEG11720.1 - 7.1 7.0 7.2 0.95 9.8 0.9 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DHHC PF01529.20 KEG11721.1 - 9.1e-27 93.8 13.6 9.1e-27 93.8 13.6 2.4 2 1 1 3 3 3 1 DHHC palmitoyltransferase Voltage_CLC PF00654.20 KEG11721.1 - 0.58 9.3 9.0 0.03 13.6 2.8 1.8 2 0 0 2 2 2 0 Voltage gated chloride channel PH PF00169.29 KEG11722.1 - 9.5e-08 32.5 0.0 2.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KEG11722.1 - 0.0003 20.8 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 KEG11722.1 - 0.00056 19.7 0.3 0.058 13.2 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KEG11722.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Prothymosin PF03247.14 KEG11722.1 - 0.1 13.0 9.3 0.2 12.1 9.3 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family PRKCSH-like PF12999.7 KEG11727.1 - 1e-11 45.0 1.2 4.6e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 KEG11727.1 - 2.9 8.2 10.7 0.41 10.9 1.2 2.4 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Pro_CA PF00484.19 KEG11729.1 - 1.3e-41 142.5 0.0 1.7e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF89 PF01937.19 KEG11730.1 - 2.8e-47 161.4 0.0 1.5e-29 103.0 0.0 4.5 4 1 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.12 KEG11730.1 - 6.1e-37 127.3 0.1 3.1e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase HAD PF12710.7 KEG11730.1 - 0.015 15.7 0.0 0.59 10.5 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SUIM_assoc PF16619.5 KEG11730.1 - 1.7 8.8 8.0 2.3 8.3 1.6 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4140 PF13600.6 KEG11731.1 - 1.9 8.9 7.1 8.1 7.0 7.1 2.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.25 KEG11733.1 - 1.2e-54 185.5 0.0 2.6e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11733.1 - 1.7e-34 119.3 0.0 4.8e-34 117.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEG11733.1 - 1.2e-09 38.4 0.1 3.1e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 KEG11733.1 - 6.9e-06 25.1 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG11733.1 - 0.00051 19.5 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PAS PF00989.25 KEG11733.1 - 0.029 14.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 PAS fold SQHop_cyclase_N PF13249.6 KEG11734.1 - 7.4e-46 156.6 0.4 2.6e-41 141.6 0.0 3.4 4 1 1 5 5 5 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KEG11734.1 - 3.7e-40 138.0 0.5 7.9e-37 127.0 0.3 3.1 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KEG11734.1 - 8.9e-21 73.3 9.0 9.5e-06 25.3 0.0 6.2 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KEG11734.1 - 0.00022 20.7 0.0 2.6 7.3 0.0 3.5 2 1 1 3 3 3 2 Pectic acid lyase PSP1 PF04468.12 KEG11736.1 - 0.00029 21.0 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Tropomyosin PF00261.20 KEG11737.1 - 0.0051 16.2 0.3 0.0051 16.2 0.3 1.7 3 0 0 3 3 3 1 Tropomyosin DUF16 PF01519.16 KEG11737.1 - 0.099 13.1 0.3 8.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 UCR_14kD PF02271.16 KEG11737.1 - 0.86 9.6 5.1 0.38 10.7 1.2 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit HlyIII PF03006.20 KEG11738.1 - 1.4e-50 172.1 27.1 1.7e-50 171.8 27.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 KEG11739.1 - 2.7e-57 194.1 28.6 3.3e-57 193.8 28.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 KEG11739.1 - 0.012 15.7 0.9 0.012 15.7 0.9 3.6 3 2 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF962 PF06127.11 KEG11739.1 - 9.7 6.4 10.1 3.3 7.8 6.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF962) PCIF1_WW PF12237.8 KEG11740.1 - 6.6e-43 146.3 0.0 1.1e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain AAA_18 PF13238.6 KEG11741.1 - 0.00036 21.1 0.3 0.0029 18.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEG11741.1 - 0.00051 19.6 0.9 0.11 11.9 0.0 2.9 2 1 1 3 3 3 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 KEG11741.1 - 0.0021 18.2 3.3 0.0059 16.8 1.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG11741.1 - 0.019 15.3 4.3 0.054 13.9 1.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 KEG11741.1 - 0.028 14.3 0.3 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KEG11741.1 - 0.13 11.6 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KEG11741.1 - 0.13 12.6 1.9 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF3886 PF13025.6 KEG11741.1 - 0.13 12.5 6.4 0.36 11.0 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) AAA PF00004.29 KEG11741.1 - 0.18 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L6e_N PF03868.15 KEG11742.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain DUF621 PF04789.15 KEG11742.1 - 0.18 10.9 0.1 0.34 10.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF621) EMP24_GP25L PF01105.24 KEG11743.1 - 8.5e-15 55.2 0.0 1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arm PF00514.23 KEG11744.1 - 0.054 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEG11744.1 - 0.21 12.1 1.7 45 4.7 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat CAP_C PF08603.11 KEG11745.1 - 8.9e-45 152.1 9.7 1.2e-44 151.7 9.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 KEG11745.1 - 2.2e-14 53.7 8.9 2.2e-14 53.7 8.9 1.9 2 1 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KEG11745.1 - 0.0032 17.5 11.3 0.0079 16.2 11.3 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 TBCC PF07986.12 KEG11745.1 - 0.04 13.6 3.2 0.07 12.9 3.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C Mtc PF03820.17 KEG11745.1 - 0.051 12.6 1.0 0.078 12.0 0.4 1.7 2 1 0 2 2 2 0 Tricarboxylate carrier CesT PF05932.13 KEG11746.1 - 1.1e-17 64.3 0.0 2.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family Adaptin_N PF01602.20 KEG11747.1 - 1.5e-70 238.2 1.7 2e-70 237.8 1.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEG11747.1 - 5.2e-35 120.9 0.0 1.5e-34 119.4 0.0 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KEG11747.1 - 6e-18 65.0 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KEG11747.1 - 2.8e-08 34.1 0.0 0.00021 21.6 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KEG11747.1 - 1.2e-05 25.1 3.4 0.085 13.2 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.8 KEG11747.1 - 0.0059 16.2 0.1 0.045 13.3 0.0 2.5 3 0 0 3 3 3 1 CLASP N terminal Cnd3 PF12719.7 KEG11747.1 - 0.0083 15.3 0.0 0.028 13.6 0.0 1.9 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain AP4E_app_platf PF14807.6 KEG11747.1 - 0.056 13.8 0.0 0.56 10.6 0.0 2.5 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform Dynactin_p22 PF07426.11 KEG11748.1 - 0.072 12.9 0.1 0.072 12.9 0.1 3.9 4 1 1 5 5 5 0 Dynactin subunit p22 Baculo_PEP_C PF04513.12 KEG11748.1 - 0.13 12.3 0.1 0.13 12.3 0.1 4.0 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KEG11748.1 - 2.9 8.4 8.8 12 6.4 0.6 3.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 LMBR1 PF04791.16 KEG11748.1 - 3.9 6.3 6.6 15 4.3 0.1 2.6 2 1 0 2 2 2 0 LMBR1-like membrane protein DUF1664 PF07889.12 KEG11748.1 - 4.6 7.3 15.1 5.9 6.9 0.1 5.0 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) EF-hand_7 PF13499.6 KEG11749.1 - 0.05 14.0 0.0 0.055 13.9 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain pair Gpi1 PF05024.15 KEG11750.1 - 1.1e-43 149.5 8.1 1.1e-43 149.5 8.1 2.2 3 0 0 3 3 3 1 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.25 KEG11751.1 - 2.1e-74 250.3 0.0 2.7e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11751.1 - 1.4e-40 139.2 0.0 2e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11751.1 - 4.1e-07 29.6 0.0 7.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEG11751.1 - 0.0018 17.9 0.5 0.011 15.3 0.1 1.9 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 KEG11751.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG11751.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG11751.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 KEG11751.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF1684 PF07920.11 KEG11751.1 - 0.18 12.1 0.0 0.48 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1684) PPR_2 PF13041.6 KEG11752.1 - 3e-05 24.1 0.4 0.053 13.7 0.0 4.0 4 1 1 5 5 5 1 PPR repeat family PPR_long PF17177.4 KEG11752.1 - 0.0014 18.0 1.8 0.1 11.9 0.3 2.7 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 KEG11752.1 - 0.0052 17.2 5.3 0.0052 17.2 5.3 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_2 PF07719.17 KEG11752.1 - 0.019 15.0 0.8 7.7 6.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KEG11752.1 - 0.027 14.7 0.1 8.7 6.9 0.0 3.6 4 0 0 4 4 4 0 PPR repeat TPR_14 PF13428.6 KEG11752.1 - 0.027 15.3 1.7 1.7 9.7 0.1 4.3 2 1 1 3 3 3 0 Tetratricopeptide repeat AbiEi_3 PF11459.8 KEG11752.1 - 0.055 13.2 0.1 0.61 9.8 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Collagen_mid PF15984.5 KEG11752.1 - 0.057 13.2 1.1 0.093 12.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial collagen, middle region TPR_19 PF14559.6 KEG11752.1 - 2 9.0 6.4 9.2 6.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 KEG11753.1 - 2.9e-21 76.0 0.1 7.1e-10 38.9 0.0 3.7 4 0 0 4 4 4 3 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 KEG11753.1 - 0.052 13.3 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KEG11753.1 - 0.13 12.3 0.2 0.68 10.0 0.2 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KEG11753.1 - 0.16 12.7 0.1 0.75 10.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEG11753.1 - 0.17 11.7 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain dCMP_cyt_deam_1 PF00383.23 KEG11754.1 - 1.2 9.1 9.1 0.18 11.7 0.7 2.8 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Radial_spoke PF04712.12 KEG11761.1 - 9.6e-11 41.3 14.2 1.2e-06 27.7 0.0 3.2 3 0 0 3 3 3 1 Radial spokehead-like protein SDA1 PF05285.12 KEG11761.1 - 0.025 14.0 7.3 0.033 13.6 7.3 1.1 1 0 0 1 1 1 0 SDA1 BNR PF02012.20 KEG11761.1 - 0.091 12.8 0.8 0.25 11.5 0.8 1.8 1 0 0 1 1 1 0 BNR/Asp-box repeat NAP PF00956.18 KEG11761.1 - 0.16 11.1 5.3 0.24 10.5 5.3 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF913 PF06025.12 KEG11761.1 - 0.16 10.9 1.1 0.21 10.5 1.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 KEG11761.1 - 0.19 11.6 8.0 0.26 11.1 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mitofilin PF09731.9 KEG11761.1 - 0.2 10.5 8.9 0.27 10.0 8.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DNA_pol_phi PF04931.13 KEG11761.1 - 0.28 9.3 12.5 0.37 8.8 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi TLP-20 PF06088.11 KEG11761.1 - 0.28 11.1 7.8 8.2 6.3 7.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.6 KEG11761.1 - 0.35 11.1 3.5 0.52 10.5 3.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KEG11761.1 - 0.52 9.0 2.8 0.68 8.6 2.8 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 KEG11761.1 - 0.58 9.6 5.0 0.8 9.1 5.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM176 PF14851.6 KEG11761.1 - 0.63 9.7 6.9 1 9.0 6.9 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 KEG11761.1 - 0.75 8.9 7.2 1.1 8.3 7.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XAP5 PF04921.14 KEG11761.1 - 0.77 9.5 5.9 1.2 9.0 5.9 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Spore_coat_CotO PF14153.6 KEG11761.1 - 0.79 9.6 16.3 1.1 9.1 16.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.8 KEG11761.1 - 0.92 8.2 8.3 1.2 7.8 8.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP1_TM PF14812.6 KEG11761.1 - 0.94 9.9 7.1 1.6 9.2 7.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cnd2 PF05786.14 KEG11761.1 - 1.5 7.4 7.4 1.9 7.0 7.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Connexin PF00029.19 KEG11761.1 - 1.5 8.5 3.3 2.2 8.0 3.3 1.2 1 0 0 1 1 1 0 Connexin RRN3 PF05327.11 KEG11761.1 - 2.6 6.5 3.6 3.2 6.2 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KEG11761.1 - 2.8 6.1 13.0 3.8 5.7 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 KEG11761.1 - 3.5 7.5 11.8 5.5 6.9 11.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 KEG11761.1 - 3.6 5.7 14.0 4.7 5.3 14.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 KEG11761.1 - 5.7 6.7 14.4 8.7 6.0 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 KEG11761.1 - 7 5.9 12.6 11 5.2 12.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 KEG11761.1 - 7.3 5.9 14.9 11 5.3 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) IML1 PF12257.8 KEG11762.1 - 9.2e-33 113.6 0.0 2.8e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 WD40 PF00400.32 KEG11763.1 - 1.8e-05 25.4 0.1 0.0037 18.1 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ERM PF00769.19 KEG11764.1 - 0.095 12.5 16.9 0.15 11.9 16.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3287 PF11690.8 KEG11764.1 - 0.29 10.9 4.2 0.53 10.0 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF3040 PF11239.8 KEG11764.1 - 3.3 8.0 5.0 6.3 7.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PKD_channel PF08016.12 KEG11765.1 - 0.087 11.5 18.9 0.018 13.8 15.0 1.7 1 1 1 2 2 2 0 Polycystin cation channel DUF1746 PF08508.10 KEG11765.1 - 0.5 10.7 7.1 0.41 11.0 0.9 3.0 2 1 1 3 3 3 0 Fungal domain of unknown function (DUF1746) DUF563 PF04577.14 KEG11766.1 - 0.0074 16.4 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SUIM_assoc PF16619.5 KEG11766.1 - 0.014 15.4 4.3 0.035 14.2 4.3 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 KEG11766.1 - 0.014 14.3 0.3 0.02 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAUGI PF06106.11 KEG11766.1 - 0.074 13.6 0.8 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 S. aureus uracil DNA glycosylase inhibitor Activator_LAG-3 PF11498.8 KEG11766.1 - 0.7 8.8 13.8 1.3 7.9 13.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 KEG11766.1 - 4.7 6.8 12.0 7.4 6.1 12.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF4577 PF15145.6 KEG11768.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF4051 PF13260.6 KEG11768.1 - 0.11 12.2 0.8 0.21 11.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) BicD PF09730.9 KEG11770.1 - 0.00025 19.6 0.9 0.00028 19.5 0.9 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Troponin PF00992.20 KEG11770.1 - 0.00099 19.4 0.9 0.0012 19.1 0.9 1.1 1 0 0 1 1 1 1 Troponin LidA_Long_CC PF18641.1 KEG11770.1 - 0.001 19.2 1.4 0.0013 18.9 1.4 1.2 1 0 0 1 1 1 1 LidA long coiled-coil domain Spc7 PF08317.11 KEG11770.1 - 0.0031 16.4 1.7 0.0034 16.3 1.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein HAP1_N PF04849.13 KEG11770.1 - 0.0039 16.4 1.4 0.0045 16.2 1.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region FapA PF03961.13 KEG11770.1 - 0.0062 15.2 0.5 0.0081 14.8 0.5 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF4763 PF15960.5 KEG11770.1 - 0.0086 15.4 0.7 0.011 15.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) CorA PF01544.18 KEG11770.1 - 0.012 14.9 1.3 0.014 14.7 1.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Golgin_A5 PF09787.9 KEG11770.1 - 0.031 13.8 3.5 0.034 13.6 3.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_HK97_TLTM PF06120.11 KEG11770.1 - 0.038 13.2 0.6 0.043 13.0 0.6 1.1 1 0 0 1 1 1 0 Tail length tape measure protein ABC_tran_CTD PF16326.5 KEG11770.1 - 0.05 13.9 3.5 0.077 13.3 3.5 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4530 PF15039.6 KEG11770.1 - 0.05 13.7 3.7 0.069 13.3 2.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) KxDL PF10241.9 KEG11770.1 - 0.055 13.7 1.6 0.12 12.6 1.3 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KEG11770.1 - 0.055 13.5 1.1 0.065 13.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3422 PF11902.8 KEG11770.1 - 0.059 12.5 1.0 0.07 12.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Spc24 PF08286.11 KEG11770.1 - 0.07 13.4 1.0 0.097 12.9 1.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PI3K_P85_iSH2 PF16454.5 KEG11770.1 - 0.075 12.6 3.9 0.15 11.6 3.5 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PelD_GGDEF PF16963.5 KEG11770.1 - 0.077 12.8 0.1 0.095 12.5 0.1 1.2 1 0 0 1 1 1 0 PelD GGDEF domain Baculo_PEP_C PF04513.12 KEG11770.1 - 0.084 12.9 1.0 0.17 12.0 0.9 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.11 KEG11770.1 - 0.088 12.8 1.3 0.11 12.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) YojJ PF10372.9 KEG11770.1 - 0.092 12.8 1.2 0.84 9.8 0.7 2.2 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus YabA PF06156.13 KEG11770.1 - 0.1 13.2 0.9 0.13 13.0 0.9 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KEG11770.1 - 0.12 12.6 4.2 0.37 11.1 2.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2721 PF11026.8 KEG11770.1 - 0.18 11.7 0.7 0.23 11.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) APG6_N PF17675.1 KEG11770.1 - 0.19 12.3 6.2 0.34 11.4 6.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region MRPL52 PF18699.1 KEG11770.1 - 0.76 10.0 4.5 1.5 9.1 3.7 1.7 1 1 1 2 2 2 0 Mitoribosomal protein mL52 SRP19 PF01922.17 KEG11771.1 - 7.6e-19 68.5 0.0 1e-18 68.1 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein PK PF00224.21 KEG11772.1 - 1.6e-151 504.1 0.8 2.1e-151 503.7 0.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KEG11772.1 - 1.3e-26 93.1 1.6 4.6e-26 91.3 0.2 2.6 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KEG11772.1 - 5e-05 22.5 0.8 0.00017 20.8 0.8 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family LPP PF04728.13 KEG11773.1 - 0.00059 20.2 0.9 0.015 15.7 0.0 3.7 3 0 0 3 3 3 1 Lipoprotein leucine-zipper EMP70 PF02990.16 KEG11774.1 - 1.6e-120 403.3 16.9 1.5e-101 340.7 8.4 2.6 2 1 1 3 3 3 2 Endomembrane protein 70 MIP PF00230.20 KEG11775.1 - 8.2e-58 195.8 6.8 1.2e-57 195.2 6.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein WD40 PF00400.32 KEG11776.1 - 8.5e-20 70.7 10.7 0.0002 22.1 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG11776.1 - 3.8e-11 43.1 0.5 0.088 13.1 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FAM53 PF15242.6 KEG11776.1 - 0.31 10.8 4.5 0.097 12.5 1.4 1.7 2 0 0 2 2 2 0 Family of FAM53 DUF4596 PF15363.6 KEG11777.1 - 0.059 13.6 0.6 0.059 13.6 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) SNARE PF05739.19 KEG11778.1 - 9.2e-11 41.6 0.0 2.7e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KEG11778.1 - 2.1e-06 27.6 16.9 2.7e-05 24.0 6.7 2.3 2 0 0 2 2 2 2 Syntaxin CENP-K PF11802.8 KEG11778.1 - 0.0086 15.7 3.3 0.043 13.4 3.3 1.9 1 1 0 1 1 1 1 Centromere-associated protein K DUF883 PF05957.13 KEG11778.1 - 0.059 14.0 2.1 0.059 14.0 2.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Sec8_exocyst PF04048.14 KEG11778.1 - 0.49 10.3 4.7 1.1 9.1 1.7 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Syntaxin-6_N PF09177.11 KEG11778.1 - 0.92 10.1 7.9 0.81 10.3 0.9 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF16 PF01519.16 KEG11778.1 - 1 9.8 10.1 3.8 8.0 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF1178 PF06676.11 KEG11778.1 - 1.3 9.4 4.4 3 8.2 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) DUF4340 PF14238.6 KEG11780.1 - 0.007 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4340) IL17R_fnIII_D2 PF16578.5 KEG11780.1 - 0.75 10.4 3.2 1.7 9.2 0.5 2.4 2 1 0 2 2 2 0 Interleukin 17 receptor D XG_FTase PF03254.13 KEG11781.1 - 6.9e-12 44.7 1.4 1.6e-05 23.7 0.0 3.0 2 1 0 3 3 3 3 Xyloglucan fucosyltransferase O-FucT PF10250.9 KEG11781.1 - 0.61 9.7 4.6 12 5.4 4.6 2.7 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase GCIP PF13324.6 KEG11782.1 - 0.15 11.6 1.9 0.27 10.8 1.9 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting WD40 PF00400.32 KEG11783.1 - 0.036 15.0 2.2 19 6.4 0.0 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat PEN-2 PF10251.9 KEG11784.1 - 1.1e-06 28.9 4.4 1.7e-06 28.3 4.4 1.4 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SAC3 PF12209.8 KEG11785.1 - 0.009 16.2 0.9 2.6 8.3 0.0 2.7 2 0 0 2 2 2 2 Leucine permease transcriptional regulator helical domain Acid_PPase PF12689.7 KEG11786.1 - 1.1e-24 87.2 0.0 1.3e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase BST2 PF16716.5 KEG11787.1 - 0.018 15.6 3.4 0.018 15.6 3.4 4.6 1 1 1 4 4 4 0 Bone marrow stromal antigen 2 HAP1_N PF04849.13 KEG11787.1 - 0.084 12.1 29.5 0.5 9.5 13.2 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 KEG11787.1 - 0.79 10.2 8.4 0.52 10.7 0.7 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KEG11787.1 - 2 8.4 17.4 3.9 7.5 3.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GldM_N PF12081.8 KEG11787.1 - 2.2 8.3 14.7 1.4 9.0 0.8 3.9 2 1 2 4 4 4 0 GldM N-terminal domain KCNQ2_u3 PF16642.5 KEG11787.1 - 2.5 9.2 7.4 0.54 11.3 2.7 2.3 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 HU-CCDC81_bac_2 PF18175.1 KEG11787.1 - 8 6.4 7.7 42 4.1 0.2 3.6 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Prominin PF05478.11 KEG11787.1 - 9 4.1 16.4 0.17 9.8 3.5 2.4 1 1 1 2 2 2 0 Prominin COG2 PF06148.11 KEG11787.1 - 9.1 6.4 17.9 0.23 11.5 4.9 3.3 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Dynein_heavy PF03028.15 KEG11788.1 - 4.1e-06 26.9 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 KEG11788.1 - 7.5e-06 26.6 10.9 1.5 9.8 0.1 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat PDZ_2 PF13180.6 KEG11788.1 - 0.0038 17.5 0.5 0.0089 16.3 0.5 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KEG11788.1 - 0.083 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain PQQ_3 PF13570.6 KEG11788.1 - 0.35 11.4 2.7 5.1 7.7 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Kinesin PF00225.23 KEG11789.1 - 1.2e-78 264.4 0.0 1.9e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG11789.1 - 4e-21 75.5 0.0 1.5e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Atg14 PF10186.9 KEG11789.1 - 0.11 11.6 7.4 1.7 7.6 2.9 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 KEG11789.1 - 0.29 11.4 3.8 4 7.8 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Fez1 PF06818.15 KEG11789.1 - 0.57 10.6 10.0 2.1 8.8 2.6 2.5 2 0 0 2 2 2 0 Fez1 MCU PF04678.13 KEG11789.1 - 1.1 9.3 4.0 1.4 9.0 1.1 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter MIP-T3_C PF17749.1 KEG11789.1 - 3.5 7.6 11.4 4.7 7.2 0.7 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Nup54 PF13874.6 KEG11789.1 - 4.3 7.4 11.5 0.27 11.3 2.8 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Kinesin PF00225.23 KEG11790.1 - 2.8e-78 263.2 0.0 2.8e-78 263.2 0.0 2.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KEG11790.1 - 3.8e-21 75.6 0.1 2.9e-20 72.7 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding DUF1192 PF06698.11 KEG11790.1 - 0.00016 21.7 0.9 0.00016 21.7 0.9 5.9 3 2 1 5 5 5 2 Protein of unknown function (DUF1192) HOOK PF05622.12 KEG11790.1 - 0.0016 16.7 25.2 0.0016 16.7 25.2 3.2 1 1 2 3 3 3 1 HOOK protein Gp58 PF07902.11 KEG11790.1 - 0.002 16.5 16.2 0.002 16.5 16.2 2.4 1 1 1 2 2 2 1 gp58-like protein Spc7 PF08317.11 KEG11790.1 - 0.0029 16.6 32.5 0.0029 16.6 32.5 3.4 1 1 3 4 4 4 3 Spc7 kinetochore protein HMMR_N PF15905.5 KEG11790.1 - 0.053 13.0 81.8 0.11 11.9 23.7 3.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 KEG11790.1 - 1.4 8.2 50.4 0.021 14.2 13.2 3.5 1 1 2 3 3 3 0 FAM76 protein ApoLp-III PF07464.11 KEG11790.1 - 3.4 7.8 61.6 0.59 10.2 7.8 5.2 1 1 3 5 5 5 0 Apolipophorin-III precursor (apoLp-III) RPGR1_C PF18111.1 KEG11791.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Retinitis pigmentosa G-protein regulator interacting C-terminal UvdE PF03851.14 KEG11792.1 - 0.16 11.2 0.5 0.25 10.6 0.5 1.1 1 0 0 1 1 1 0 UV-endonuclease UvdE DUF4088 PF13317.6 KEG11793.1 - 0.0039 16.8 0.3 0.01 15.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4088) DUF4370 PF14290.6 KEG11793.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) CAGE1 PF15066.6 KEG11793.1 - 0.063 11.9 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DUF2499 PF10693.9 KEG11794.1 - 0.072 13.4 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) Myosin_TH1 PF06017.13 KEG11797.1 - 1.8e-21 76.6 0.1 1.2e-07 31.7 0.0 3.5 3 0 0 3 3 3 3 Unconventional myosin tail, actin- and lipid-binding PH PF00169.29 KEG11797.1 - 0.00015 22.2 0.0 0.0013 19.2 0.0 2.5 2 0 0 2 2 2 1 PH domain RUN PF02759.19 KEG11797.1 - 0.0032 17.4 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 2 RUN domain Thymidylate_kin PF02223.17 KEG11799.1 - 0.07 12.8 0.7 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase RNA_GG_bind PF10258.9 KEG11802.1 - 0.17 11.9 0.5 0.44 10.6 0.1 1.7 2 0 0 2 2 2 0 PHAX RNA-binding domain SUV3_C PF12513.8 KEG11804.1 - 0.23 11.4 0.2 0.42 10.6 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal RPN2_C PF18004.1 KEG11805.1 - 3.4e-33 114.8 4.2 3.4e-33 114.8 4.2 1.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KEG11805.1 - 2.3e-18 65.6 16.2 0.00014 22.1 0.2 7.6 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KEG11805.1 - 8.9e-14 51.7 3.1 7.2e-10 39.1 0.0 5.2 3 1 2 6 6 6 1 HEAT repeats Methyltr_RsmB-F PF01189.17 KEG11806.1 - 5.7e-05 22.9 0.1 0.0001 22.0 0.1 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ribosomal_60s PF00428.19 KEG11807.1 - 0.0013 19.3 8.7 0.0053 17.3 2.2 3.1 3 0 0 3 3 3 1 60s Acidic ribosomal protein zf-C2H2_assoc3 PF16637.5 KEG11807.1 - 0.083 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Pkinase PF00069.25 KEG11808.1 - 6.7e-15 55.2 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11808.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG11808.1 - 0.047 13.6 0.8 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEG11808.1 - 0.25 10.4 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 KEG11808.1 - 0.32 12.0 3.3 0.42 11.6 0.1 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat ArfGap PF01412.18 KEG11809.1 - 2e-38 131.1 0.9 3.6e-38 130.2 0.9 1.5 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf DUF21 PF01595.20 KEG11810.1 - 5.5e-34 117.4 0.3 1.1e-33 116.4 0.3 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEG11810.1 - 9.2e-07 29.2 0.2 0.0024 18.3 0.1 2.8 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 KEG11810.1 - 0.0024 17.9 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1035 PF06281.12 KEG11810.1 - 0.12 12.4 0.8 0.4 10.7 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) SUIM_assoc PF16619.5 KEG11811.1 - 9.8e-05 22.4 0.8 0.0002 21.4 0.8 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Pox_A11 PF05061.13 KEG11811.1 - 0.29 10.4 0.5 0.4 9.9 0.5 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein FliX PF10768.9 KEG11811.1 - 0.62 10.6 7.0 0.6 10.6 1.8 2.4 2 1 0 2 2 2 0 Class II flagellar assembly regulator Vps52 PF04129.12 KEG11812.1 - 6.3e-20 71.4 1.1 1.7e-18 66.7 1.1 2.7 1 1 0 1 1 1 1 Vps52 / Sac2 family FAD_binding_1 PF00667.20 KEG11813.1 - 8.1e-39 133.5 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEG11813.1 - 1.2e-23 83.9 0.0 3.4e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KEG11813.1 - 2.6e-15 57.0 0.0 6.1e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.32 KEG11814.1 - 2.3e-15 56.7 1.4 6.5e-05 23.6 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat RRM_1 PF00076.22 KEG11816.1 - 4.4e-11 42.4 0.1 8.4e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 KEG11816.1 - 0.002 18.5 7.2 0.0094 16.3 7.1 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 KEG11816.1 - 0.0092 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif SET_assoc PF11767.8 KEG11816.1 - 0.012 15.3 0.1 0.039 13.6 0.0 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PIEZO PF15917.5 KEG11816.1 - 3 7.3 5.6 0.4 10.1 1.7 1.5 2 0 0 2 2 2 0 Piezo MFS_1 PF07690.16 KEG11818.1 - 2e-24 86.2 30.1 2.3e-22 79.4 22.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KEG11822.1 - 0.00016 22.4 7.8 15 6.6 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat Las1 PF04031.13 KEG11822.1 - 0.13 12.4 0.0 2.9 8.0 0.0 2.5 3 0 0 3 3 3 0 Las1-like EMP70 PF02990.16 KEG11824.1 - 5.4e-117 391.6 3.5 7.6e-117 391.1 3.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sin_N PF04801.13 KEG11825.1 - 3.4e-83 280.3 0.0 3.2e-82 277.1 0.0 1.9 2 0 0 2 2 2 1 Sin-like protein conserved region Ge1_WD40 PF16529.5 KEG11826.1 - 0.0041 16.1 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_19 PF13245.6 KEG11826.1 - 0.0059 17.0 2.8 1.4 9.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain Med11 PF10280.9 KEG11826.1 - 0.086 13.3 2.3 0.2 12.1 0.5 2.2 2 0 0 2 2 2 0 Mediator complex protein Dpy-30 PF05186.13 KEG11827.1 - 5.9e-16 57.9 0.1 1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif AAA_28 PF13521.6 KEG11827.1 - 0.00029 21.1 1.7 0.0012 19.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain RIIa PF02197.17 KEG11827.1 - 0.00033 20.2 0.0 0.00092 18.8 0.0 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ADK PF00406.22 KEG11827.1 - 0.00063 19.9 0.0 0.064 13.4 0.0 3.4 3 0 0 3 3 3 1 Adenylate kinase AAA_18 PF13238.6 KEG11827.1 - 0.00082 19.9 0.4 0.69 10.5 0.0 4.2 3 2 1 4 4 4 1 AAA domain 3Beta_HSD PF01073.19 KEG11827.1 - 0.0051 15.8 0.0 0.019 14.0 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEG11827.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_17 PF13207.6 KEG11827.1 - 0.069 13.6 2.4 2.2 8.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 KEG11827.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.9 4 1 0 4 4 4 0 Hydin Adenylate kinase-like domain Exonuc_VII_L PF02601.15 KEG11827.1 - 3.8 7.0 7.4 1.4 8.4 3.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit FKBP_C PF00254.28 KEG11828.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF5320 PF17253.2 KEG11828.1 - 0.42 11.7 3.1 0.78 10.8 2.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) HAUS2 PF15003.6 KEG11828.1 - 3.8 7.2 8.3 0.14 11.8 1.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 DUF1664 PF07889.12 KEG11828.1 - 5.5 7.1 13.0 5.8 7.0 1.8 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF1769 PF08588.10 KEG11829.1 - 0.075 13.2 0.0 0.28 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) ACBP PF00887.19 KEG11830.1 - 5.1e-16 58.7 0.0 8.8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein S10_plectin PF03501.15 KEG11831.1 - 4.7e-35 119.5 0.0 5.4e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.11 KEG11831.1 - 3.6 6.3 5.1 4.3 6.0 5.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Spc24 PF08286.11 KEG11832.1 - 0.02 15.1 1.6 0.034 14.4 1.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 VAPB_antitox PF02697.14 KEG11833.1 - 0.05 14.4 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin INCENP_ARK-bind PF03941.15 KEG11833.1 - 0.11 12.5 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region AAA_6 PF12774.7 KEG11834.1 - 6.7e-154 511.7 0.0 2.9e-153 509.6 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG11834.1 - 1.1e-118 396.9 13.8 1.1e-118 396.9 13.8 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KEG11834.1 - 8e-111 370.1 0.4 2.7e-107 358.5 0.0 3.3 3 0 0 3 3 3 2 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KEG11834.1 - 3.1e-100 334.8 0.0 2.1e-99 332.1 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KEG11834.1 - 9.8e-84 279.9 2.6 1.7e-81 272.6 0.4 3.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KEG11834.1 - 4.8e-70 234.7 3.6 8.8e-68 227.4 0.0 4.1 5 0 0 5 5 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG11834.1 - 5.7e-53 179.1 0.0 1.8e-52 177.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG11834.1 - 4e-49 165.6 0.1 1.4e-46 157.5 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KEG11834.1 - 2.7e-43 148.3 6.9 4.6e-43 147.6 6.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KEG11834.1 - 1.1e-24 87.0 1.7 3.3e-23 82.2 0.0 3.8 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KEG11834.1 - 1.8e-14 53.9 0.0 0.0032 17.5 0.0 6.6 5 2 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KEG11834.1 - 2.6e-14 53.2 0.1 1.3e-13 50.9 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 KEG11834.1 - 4.5e-09 36.7 0.6 0.00048 20.4 0.0 5.4 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.22 KEG11834.1 - 7.5e-06 26.3 0.0 0.13 12.6 0.0 4.5 4 0 0 4 4 3 2 RNA helicase AAA PF00004.29 KEG11834.1 - 7.8e-06 26.3 0.0 0.51 10.8 0.0 3.9 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG11834.1 - 3.6e-05 24.2 0.5 1.5 9.2 0.0 4.6 5 0 0 5 5 3 2 AAA ATPase domain NACHT PF05729.12 KEG11834.1 - 0.00036 20.5 0.3 0.045 13.7 0.0 3.3 3 0 0 3 3 2 1 NACHT domain AAA_30 PF13604.6 KEG11834.1 - 0.0023 17.7 0.0 0.73 9.5 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEG11834.1 - 0.0028 18.2 0.0 2 8.9 0.0 4.9 5 0 0 5 5 3 1 AAA domain AAA_14 PF13173.6 KEG11834.1 - 0.0037 17.3 0.0 0.81 9.7 0.0 3.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEG11834.1 - 0.005 15.9 0.0 0.12 11.4 0.0 3.1 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_33 PF13671.6 KEG11834.1 - 0.01 16.0 0.0 2.7 8.2 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KEG11834.1 - 0.067 12.9 0.0 9.1 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KEG11834.1 - 0.1 11.9 0.1 0.44 9.9 0.0 2.1 2 0 0 2 2 1 0 FtsK/SpoIIIE family DUF2730 PF10805.8 KEG11834.1 - 0.86 9.7 6.5 16 5.7 0.2 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) AAA_25 PF13481.6 KEG11834.1 - 1.3 8.5 3.2 10 5.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF853 PF05872.12 KEG11834.1 - 2.2 6.7 8.4 1.2 7.7 0.0 2.8 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 KEG11834.1 - 3.6 7.9 6.2 58 4.0 0.1 4.4 5 0 0 5 5 3 0 AAA domain Ribosomal_S13 PF00416.22 KEG11835.1 - 1.2e-47 161.5 5.6 2.1e-27 96.0 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 PGM_PMM_II PF02879.16 KEG11835.1 - 0.062 13.9 0.0 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ubiquitin PF00240.23 KEG11836.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family Ubiquitin_5 PF18037.1 KEG11836.1 - 0.081 13.3 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Ribonuclease_3 PF00636.26 KEG11837.1 - 0.00041 20.9 0.0 0.022 15.4 0.0 2.7 1 1 0 1 1 1 1 Ribonuclease III domain Metallophos PF00149.28 KEG11838.1 - 1e-16 62.0 0.1 1.3e-16 61.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEG11838.1 - 1.7e-14 54.0 0.7 2.3e-14 53.5 0.7 1.2 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain FGase PF05013.12 KEG11839.1 - 0.042 14.1 0.4 0.052 13.8 0.4 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase DUF2203 PF09969.9 KEG11839.1 - 0.4 11.4 4.0 1.1 10.0 4.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1515 PF07439.11 KEG11839.1 - 0.41 10.7 1.7 0.69 10.0 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) NAD_binding_10 PF13460.6 KEG11840.1 - 1.5e-11 44.5 0.0 5.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 KEG11840.1 - 0.00033 19.8 0.0 0.0031 16.5 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEG11840.1 - 0.0021 17.5 0.1 0.021 14.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KEG11840.1 - 0.0022 18.5 0.0 0.66 10.6 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KEG11840.1 - 0.0061 16.1 0.8 0.054 13.0 0.8 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KEG11840.1 - 0.0098 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein DUF2255 PF10012.9 KEG11840.1 - 0.029 14.5 1.9 0.38 10.9 0.6 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2255) Rz1 PF06085.11 KEG11841.1 - 0.012 15.4 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor CBF PF03914.17 KEG11842.1 - 2.9e-28 99.0 1.2 9e-28 97.4 0.2 2.0 2 0 0 2 2 2 1 CBF/Mak21 family SpoIIE PF07228.12 KEG11843.1 - 5.1e-09 36.3 0.1 6.9e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEG11843.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Tcp10_C PF07202.13 KEG11844.1 - 0.0021 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Dynein_light PF01221.18 KEG11845.1 - 0.07 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Dynein light chain type 1 SIP1 PF04938.12 KEG11846.1 - 0.067 12.9 0.2 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) EF-hand_9 PF14658.6 KEG11846.1 - 0.15 12.4 0.0 0.58 10.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain FliG_N PF14842.6 KEG11846.1 - 0.21 12.1 2.4 7 7.2 0.0 3.8 3 1 1 4 4 4 0 FliG N-terminal domain Alk_phosphatase PF00245.20 KEG11846.1 - 0.49 9.3 2.4 0.87 8.5 2.4 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Transmemb_17 PF09799.9 KEG11847.1 - 8.8e-21 74.5 10.2 1.2e-20 74.1 10.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein MFS_1 PF07690.16 KEG11847.1 - 0.058 12.3 10.2 0.088 11.7 10.2 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Cytochrom_B558a PF05038.13 KEG11847.1 - 0.086 12.4 2.6 0.11 12.1 2.6 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Yip1 PF04893.17 KEG11847.1 - 3.2 7.4 17.6 5.4 6.7 16.5 1.7 1 1 1 2 2 2 0 Yip1 domain DUF2039 PF10217.9 KEG11848.1 - 9.4e-23 80.4 17.6 1.8e-22 79.5 17.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) CDC45 PF02724.14 KEG11848.1 - 1.8 6.8 6.8 2 6.6 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3584 PF12128.8 KEG11850.1 - 4.4e-06 24.5 67.1 4.4e-06 24.5 67.1 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 KEG11850.1 - 0.00061 18.8 24.8 0.00061 18.8 24.8 7.1 4 2 2 7 7 7 2 Spc7 kinetochore protein FTA4 PF13093.6 KEG11850.1 - 0.0018 18.2 0.2 0.0018 18.2 0.2 7.2 4 1 1 5 5 5 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FliJ PF02050.16 KEG11850.1 - 0.002 18.3 19.1 0.002 18.3 19.1 8.9 5 2 3 9 9 9 1 Flagellar FliJ protein Lebercilin PF15619.6 KEG11850.1 - 0.0033 17.1 6.7 0.0033 17.1 6.7 8.4 6 2 2 8 8 8 1 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 KEG11850.1 - 0.0054 17.3 9.4 0.0054 17.3 9.4 10.7 6 1 3 9 9 9 2 Initiation control protein YabA FlxA PF14282.6 KEG11850.1 - 0.0068 16.4 11.4 0.0068 16.4 11.4 8.3 5 2 2 8 8 8 1 FlxA-like protein Fe_dep_repress PF01325.19 KEG11850.1 - 0.66 10.2 11.4 50 4.2 0.6 5.1 2 2 3 6 6 6 0 Iron dependent repressor, N-terminal DNA binding domain Fez1 PF06818.15 KEG11850.1 - 1.7 9.1 146.1 0.077 13.4 32.6 7.7 4 1 3 7 7 7 0 Fez1 APG6_N PF17675.1 KEG11850.1 - 8.6 6.9 198.4 0.049 14.2 21.7 10.5 4 1 4 9 9 9 0 Apg6 coiled-coil region PSP1 PF04468.12 KEG11851.1 - 5e-24 84.4 0.8 9.5e-24 83.5 0.8 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Peptidase_M24 PF00557.24 KEG11852.1 - 7e-12 45.5 0.1 1.8e-11 44.1 0.1 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 TetR_C_33 PF13305.6 KEG11852.1 - 0.47 11.2 3.9 2.6 8.8 3.9 2.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NOA36 PF06524.12 KEG11853.1 - 1.1 8.5 13.4 1.1 8.5 13.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nop53 PF07767.11 KEG11853.1 - 1.7 8.0 22.2 1.9 7.8 22.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GCIP PF13324.6 KEG11853.1 - 3.4 7.2 8.3 3.9 7.0 8.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 KEG11853.1 - 8 4.4 16.0 8.5 4.3 16.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Lectin_leg-like PF03388.13 KEG11854.1 - 1.4e-46 158.7 0.5 2.1e-46 158.1 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family Bact_lectin PF18483.1 KEG11854.1 - 2.3e-14 53.9 0.5 2.3e-14 53.9 0.5 1.4 2 0 0 2 2 2 1 Bacterial lectin LCE PF14672.6 KEG11854.1 - 3.2 8.4 9.2 7.5 7.2 9.2 1.5 1 0 0 1 1 1 0 Late cornified envelope U-box PF04564.15 KEG11855.1 - 1.2e-07 31.7 0.0 3.2e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KEG11855.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit KNOX2 PF03791.13 KEG11855.1 - 0.13 11.7 2.5 1.7 8.2 0.2 2.8 2 0 0 2 2 2 0 KNOX2 domain DHHC PF01529.20 KEG11856.1 - 4.9e-31 107.6 3.1 4.9e-31 107.6 3.1 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF5320 PF17253.2 KEG11856.1 - 0.0083 17.2 2.9 0.096 13.8 0.0 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5320) HemY_N PF07219.13 KEG11856.1 - 5.4 7.3 7.6 10 6.4 0.1 3.2 3 0 0 3 3 3 0 HemY protein N-terminus Cse1 PF08506.10 KEG11857.1 - 0.0025 16.7 0.4 0.0098 14.8 0.0 2.3 3 0 0 3 3 3 1 Cse1 BUD22 PF09073.10 KEG11857.1 - 0.0083 15.5 12.5 0.012 15.0 12.5 1.2 1 0 0 1 1 1 1 BUD22 DUF1338 PF07063.13 KEG11857.1 - 0.092 11.9 0.2 0.22 10.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) SDA1 PF05285.12 KEG11857.1 - 0.11 11.8 15.6 0.18 11.2 15.6 1.2 1 0 0 1 1 1 0 SDA1 SnoaL_2 PF12680.7 KEG11858.1 - 0.032 14.9 2.9 4 8.1 0.0 4.1 3 1 1 4 4 4 0 SnoaL-like domain TSC22 PF01166.18 KEG11858.1 - 0.21 11.9 3.5 0.22 11.8 0.2 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family GAS PF13851.6 KEG11858.1 - 3.7 6.9 16.9 0.47 9.8 0.4 3.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Presenilin PF01080.17 KEG11860.1 - 7.7 5.2 6.3 9.9 4.8 6.3 1.0 1 0 0 1 1 1 0 Presenilin COX17 PF05051.13 KEG11861.1 - 2.9e-14 53.1 22.7 3.7e-14 52.8 8.1 2.1 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) tRNA_edit PF04073.15 KEG11864.1 - 1.2e-22 80.3 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain NosD PF05048.13 KEG11865.1 - 0.051 12.8 0.7 11 5.2 0.0 3.4 3 0 0 3 3 3 0 Periplasmic copper-binding protein (NosD) DUF1729 PF08354.10 KEG11865.1 - 0.18 10.7 0.4 0.29 10.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) PGAP1 PF07819.13 KEG11866.1 - 4.4e-31 108.4 0.2 7.2e-31 107.7 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEG11866.1 - 3.6e-05 24.5 5.2 8.4e-05 23.3 0.0 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEG11866.1 - 0.0002 20.7 0.1 0.00042 19.7 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG11866.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KEG11866.1 - 0.0042 16.9 0.1 0.0086 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KEG11866.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 KEG11866.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 KEG11866.1 - 0.2 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DEAD PF00270.29 KEG11867.1 - 2.6e-17 63.2 0.0 8.7e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG11867.1 - 1.5e-09 38.0 0.0 1.2e-08 35.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEG11867.1 - 1.2e-07 32.0 0.1 2.9e-06 27.6 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEG11867.1 - 0.048 13.9 0.1 0.77 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF501 PF04417.12 KEG11867.1 - 6.5 6.6 9.0 5.3 6.8 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF501) ATP_synt_H PF05493.13 KEG11868.1 - 3.3e-19 69.1 3.5 3.6e-19 69.0 3.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF3099 PF11298.8 KEG11868.1 - 1.2 9.3 5.8 0.65 10.2 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) WD40 PF00400.32 KEG11869.1 - 5e-14 52.5 11.6 0.00068 20.4 0.0 6.2 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG11869.1 - 8.3e-07 29.2 0.3 0.057 13.7 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG11869.1 - 0.09 11.7 0.0 0.78 8.6 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Phage_holin_3_6 PF07332.11 KEG11870.1 - 0.56 10.3 3.2 0.91 9.6 3.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RHH_1 PF01402.21 KEG11871.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Ank_4 PF13637.6 KEG11872.1 - 1.3e-16 60.7 0.4 1.9e-11 44.2 0.2 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG11872.1 - 4.7e-13 49.5 0.4 7.3e-12 45.7 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG11872.1 - 6.4e-13 48.7 1.0 2.9e-07 30.6 0.1 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG11872.1 - 1.6e-10 40.3 0.1 0.0019 18.5 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KEG11872.1 - 1.9e-07 31.2 0.1 0.006 17.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Metallophos PF00149.28 KEG11873.1 - 5.5e-38 131.5 0.1 7e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEG11873.1 - 1.6e-16 60.4 0.4 2.7e-16 59.7 0.4 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB_2 PF02214.22 KEG11874.1 - 2.4e-11 43.8 0.0 4.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.6 KEG11875.1 - 1.1e-19 70.2 0.6 1.6e-19 69.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.11 KEG11876.1 - 7.3e-09 36.1 1.2 7.3e-09 36.1 1.2 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein EF-hand_5 PF13202.6 KEG11876.1 - 0.0024 17.3 0.0 0.0055 16.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEG11876.1 - 0.0027 17.5 0.0 0.008 16.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KEG11876.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KEG11876.1 - 0.014 15.9 0.3 0.046 14.2 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair Sas10_Utp3 PF04000.15 KEG11877.1 - 9.2e-18 64.7 1.1 9.2e-18 64.7 1.1 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.10 KEG11877.1 - 5.9e-16 58.7 5.1 2.3e-15 56.8 5.1 2.1 1 0 0 1 1 1 1 Sas10 C-terminal domain MCU PF04678.13 KEG11877.1 - 0.27 11.3 3.9 2 8.5 0.2 2.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter YqcI_YcgG PF08892.11 KEG11878.1 - 0.11 12.3 1.0 0.18 11.6 0.2 1.6 2 0 0 2 2 2 0 YqcI/YcgG family SNF2_N PF00176.23 KEG11882.1 - 3.3e-54 183.9 0.0 5e-53 180.0 0.0 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG11882.1 - 2.2e-15 57.0 0.1 1e-14 54.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KEG11882.1 - 9.1e-07 28.7 4.6 2.6e-06 27.2 4.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KEG11882.1 - 9.5e-07 29.0 0.3 1.1e-05 25.5 0.1 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KEG11882.1 - 4.7e-06 26.4 4.4 1e-05 25.3 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG11882.1 - 1.1e-05 25.4 1.2 1.1e-05 25.4 1.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEG11882.1 - 1.8e-05 24.6 5.3 4.4e-05 23.4 5.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KEG11882.1 - 5.1e-05 23.1 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KEG11882.1 - 6.5e-05 23.2 5.6 6.5e-05 23.2 5.6 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG11882.1 - 0.00032 20.5 7.2 0.00053 19.8 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG11882.1 - 0.00059 19.7 4.1 0.0017 18.1 4.1 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 KEG11882.1 - 0.00068 19.8 4.0 0.00068 19.8 4.0 2.0 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ERCC3_RAD25_C PF16203.5 KEG11882.1 - 0.0027 16.9 0.1 0.0077 15.5 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_4 PF15227.6 KEG11882.1 - 0.011 15.9 5.1 0.023 14.9 4.7 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1492 PF07374.11 KEG11882.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) zf-RING_10 PF16685.5 KEG11882.1 - 1.4 9.1 5.5 1.2 9.3 3.3 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KEG11882.1 - 1.6 9.1 6.7 1.3 9.4 4.3 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain PGK PF00162.19 KEG11884.1 - 7.3e-104 347.7 0.0 9.6e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase cNMP_binding PF00027.29 KEG11884.1 - 2.5e-05 24.2 0.0 6.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_9 PF14580.6 KEG11885.1 - 0.00011 21.8 0.1 0.00021 20.8 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KEG11885.1 - 0.0018 18.6 2.5 0.015 15.7 0.1 2.8 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11885.1 - 0.053 13.3 2.4 0.8 9.5 2.4 2.5 1 1 0 1 1 1 0 Leucine rich repeat Torus PF16131.5 KEG11885.1 - 0.065 13.9 0.3 0.12 13.1 0.3 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KEG11885.1 - 0.072 13.6 6.0 0.14 12.7 6.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KEG11885.1 - 0.16 12.2 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family tRNA_synthFbeta PF17759.1 KEG11886.1 - 5.3e-43 146.9 0.0 8.1e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KEG11886.1 - 8.9e-35 118.8 0.1 1.4e-32 111.7 0.1 2.4 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KEG11886.1 - 2.1e-20 72.8 0.1 1.6e-16 60.4 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 KEG11886.1 - 3.9e-18 65.7 0.0 6.6e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain Cir_N PF10197.9 KEG11887.1 - 0.02 15.1 3.0 0.02 15.1 3.0 4.0 4 1 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR HAUS-augmin3 PF14932.6 KEG11887.1 - 0.35 10.4 8.5 0.03 13.9 2.6 2.1 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 LRR_9 PF14580.6 KEG11888.1 - 4.9e-07 29.4 0.1 9.3e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KEG11888.1 - 0.0095 16.3 2.0 0.066 13.7 1.9 2.5 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) RasGEF PF00617.19 KEG11889.1 - 6.6e-18 65.5 0.0 1.2e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEG11889.1 - 0.00012 22.3 0.8 0.00025 21.2 0.8 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif ThiF PF00899.21 KEG11890.1 - 3e-59 200.3 0.1 4.3e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KEG11890.1 - 0.00057 20.4 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain NINJA_B PF16136.5 KEG11890.1 - 0.0089 16.4 1.4 0.019 15.3 1.4 1.5 1 0 0 1 1 1 1 Putative nuclear localisation signal Sacchrp_dh_NADP PF03435.18 KEG11890.1 - 0.026 14.8 0.4 0.082 13.2 0.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KEG11890.1 - 0.071 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEG11890.1 - 0.091 12.0 0.4 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain DUF4796 PF16044.5 KEG11890.1 - 0.11 12.0 0.0 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) Strumpellin PF10266.9 KEG11891.1 - 0 1425.4 2.2 0 1425.2 2.2 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin NPV_P10 PF05531.12 KEG11891.1 - 0.076 13.5 0.3 2.1 8.8 0.0 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Ribosomal_S5_C PF03719.15 KEG11891.1 - 0.1 12.1 0.0 9.6 5.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain COG5 PF10392.9 KEG11891.1 - 1.5 9.0 5.1 15 5.7 0.3 3.7 4 0 0 4 4 4 0 Golgi transport complex subunit 5 TssO PF17561.2 KEG11893.1 - 1.5 8.9 4.6 0.77 9.9 0.4 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssO Allantoicase PF03561.15 KEG11893.1 - 5.1 7.1 8.8 0.4 10.6 3.4 1.8 2 1 0 2 2 2 0 Allantoicase repeat GAS PF13851.6 KEG11894.1 - 0.013 14.9 7.1 0.016 14.6 7.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1043 PF06295.12 KEG11894.1 - 0.059 13.4 4.5 0.3 11.1 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 KEG11894.1 - 0.088 12.8 1.8 0.11 12.5 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CCDC158 PF15921.5 KEG11894.1 - 0.17 9.7 6.3 0.21 9.4 6.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 TPR_MLP1_2 PF07926.12 KEG11894.1 - 0.17 11.9 9.1 0.15 12.1 7.9 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 KEG11894.1 - 0.32 11.3 3.1 2.9 8.2 1.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein UPF0242 PF06785.11 KEG11894.1 - 0.96 9.5 6.8 1 9.5 6.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MMR_HSR1 PF01926.23 KEG11895.1 - 2e-16 60.1 0.0 5.2e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEG11895.1 - 1.2e-08 35.2 0.0 3.7e-06 27.1 0.0 2.8 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KEG11895.1 - 0.00031 20.7 0.0 0.0068 16.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEG11895.1 - 0.00053 19.6 0.0 0.0083 15.7 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KEG11895.1 - 0.0011 18.3 0.0 0.0037 16.6 0.0 1.9 1 1 0 1 1 1 1 AIG1 family Septin PF00735.18 KEG11895.1 - 0.0034 16.7 0.0 0.0076 15.6 0.0 1.6 1 0 0 1 1 1 1 Septin Roc PF08477.13 KEG11895.1 - 0.033 14.4 0.0 0.094 12.9 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KEG11895.1 - 0.063 13.8 0.0 0.34 11.4 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.21 KEG11895.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase MMR_HSR1 PF01926.23 KEG11897.1 - 0.044 13.9 0.1 0.86 9.7 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase YbaB_DNA_bd PF02575.16 KEG11900.1 - 6.9e-05 23.0 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family CHASE8 PF17152.4 KEG11900.1 - 0.13 12.5 0.0 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 Periplasmic sensor domain LCE6A PF15858.5 KEG11901.1 - 2.7 8.8 7.5 3.3 8.5 3.5 3.1 2 1 1 3 3 3 0 Late cornified envelope protein 6A family Myc_N PF01056.18 KEG11902.1 - 3.7 7.4 10.2 7.5 6.4 10.3 1.6 1 1 0 1 1 1 0 Myc amino-terminal region Ribosomal_L39 PF00832.20 KEG11902.1 - 4.2 7.1 6.0 0.55 9.9 0.9 2.1 2 0 0 2 2 2 0 Ribosomal L39 protein DUF4746 PF15928.5 KEG11902.1 - 6.4 6.1 11.5 2.1 7.7 9.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_M8 PF01457.16 KEG11903.1 - 1.2e-142 476.4 1.7 5.8e-86 289.3 0.0 2.1 1 1 1 2 2 2 2 Leishmanolysin NAD_Gly3P_dh_N PF01210.23 KEG11909.1 - 1.6e-44 151.6 0.0 3.9e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KEG11909.1 - 1.9e-43 148.2 1.2 3.2e-43 147.4 1.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_binding_2 PF03446.15 KEG11909.1 - 0.00016 21.9 0.2 0.0071 16.5 0.1 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEG11909.1 - 0.00048 20.7 0.3 0.0028 18.2 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1495 PF07381.11 KEG11909.1 - 0.01 15.6 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) UDPG_MGDP_dh_N PF03721.14 KEG11909.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KEG11909.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4774 PF15999.5 KEG11909.1 - 0.059 13.2 1.1 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4774) DegS PF05384.11 KEG11909.1 - 0.072 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Sensor protein DegS PAC2 PF09754.9 KEG11909.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 PAC2 family 3HCDH_N PF02737.18 KEG11909.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dna2 PF08696.11 KEG11911.1 - 0.015 15.2 0.0 0.042 13.7 0.0 1.7 1 1 0 1 1 1 0 DNA replication factor Dna2 BRF1 PF07741.13 KEG11911.1 - 0.038 14.3 1.0 0.064 13.6 1.0 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Ribosomal_60s PF00428.19 KEG11911.1 - 0.47 11.1 7.4 0.42 11.2 5.3 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein UCH PF00443.29 KEG11912.1 - 2.2e-44 151.9 0.0 2.9e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG11912.1 - 1.1e-18 67.9 0.0 8.3e-18 65.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Piwi PF02171.17 KEG11913.1 - 2.1e-13 50.2 0.0 3.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Piwi domain TIMELESS_C PF05029.13 KEG11913.1 - 0.052 12.7 1.3 0.088 12.0 1.3 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region PRODH PF18327.1 KEG11913.1 - 0.25 11.6 3.1 6.5 7.1 0.1 2.9 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain Pyr_redox_2 PF07992.14 KEG11914.1 - 9.2e-14 51.4 0.9 9.8e-12 44.7 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG11914.1 - 6.9e-07 29.4 0.0 3.4e-06 27.2 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEG11914.1 - 5e-05 23.8 0.0 0.21 12.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEG11914.1 - 0.00031 20.8 0.0 0.0009 19.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KEG11914.1 - 0.00072 19.2 0.1 0.038 13.6 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KEG11914.1 - 0.0012 18.1 0.1 0.0029 16.8 0.1 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEG11914.1 - 0.0034 16.7 0.1 0.08 12.2 0.0 2.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KEG11914.1 - 0.0038 16.3 0.0 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEG11914.1 - 0.0058 15.9 0.7 0.24 10.6 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KEG11914.1 - 0.086 12.9 0.4 17 5.5 0.0 3.5 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KEG11914.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NTF2 PF02136.20 KEG11915.1 - 2.8e-09 37.6 0.1 5.1e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF501 PF04417.12 KEG11915.1 - 0.0028 17.4 2.7 0.0048 16.7 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF501) TMEM189_B_dmain PF10520.9 KEG11916.1 - 3.6e-61 206.3 3.4 5.6e-61 205.7 3.4 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain Keratin_assoc PF09775.9 KEG11916.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Mtp PF03821.16 KEG11916.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Golgi 4-transmembrane spanning transporter FA_hydroxylase PF04116.13 KEG11916.1 - 0.14 12.5 11.2 0.28 11.5 5.7 2.4 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily zf-B_box PF00643.24 KEG11917.1 - 0.0022 18.1 4.4 0.0022 18.1 4.4 6.5 5 2 0 5 5 5 1 B-box zinc finger ubiquitin PF00240.23 KEG11917.1 - 0.0035 17.0 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Vps35 PF03635.17 KEG11920.1 - 1e-224 748.4 0.0 1.1e-224 748.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 CBF PF03914.17 KEG11920.1 - 0.023 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 CBF/Mak21 family F-box PF00646.33 KEG11922.1 - 0.099 12.6 0.0 4.1 7.4 0.0 2.4 1 1 1 2 2 2 0 F-box domain Arf PF00025.21 KEG11923.1 - 2.8e-68 228.8 0.1 3.1e-68 228.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG11923.1 - 2.8e-13 50.1 0.0 4.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEG11923.1 - 5.6e-12 45.5 0.0 6.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KEG11923.1 - 1.5e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KEG11923.1 - 5.6e-10 38.9 0.4 6.5e-07 28.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KEG11923.1 - 5.3e-08 32.5 0.0 7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG11923.1 - 2.4e-05 24.4 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG11923.1 - 0.036 13.6 0.7 0.19 11.2 0.7 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 KEG11924.1 - 5.2e-75 252.2 0.0 6.7e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11924.1 - 1.9e-41 142.1 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11924.1 - 4.9e-07 29.4 0.0 6.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 KEG11924.1 - 0.0015 18.5 2.0 1.2 9.3 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 KEG11924.1 - 0.0052 17.2 0.2 0.013 15.9 0.2 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) Kdo PF06293.14 KEG11924.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG11924.1 - 0.016 15.2 0.1 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KEG11924.1 - 0.062 12.9 0.0 0.79 9.3 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_8 PF13855.6 KEG11924.1 - 0.09 12.6 2.5 0.89 9.4 1.6 2.4 1 1 0 1 1 1 0 Leucine rich repeat Haspin_kinase PF12330.8 KEG11924.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KEG11924.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KEG11924.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DnaJ PF00226.31 KEG11926.1 - 6.2e-07 29.5 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain BRI3BP PF14965.6 KEG11926.1 - 0.056 13.0 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DEC1 PF15859.5 KEG11926.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family DUF3040 PF11239.8 KEG11926.1 - 1 9.7 4.0 7.7 6.9 1.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) zf-RING_2 PF13639.6 KEG11927.1 - 1.5e-11 44.4 5.1 4.2e-11 43.0 5.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KEG11927.1 - 4.4e-11 42.6 1.8 3.4e-10 39.8 0.7 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEG11927.1 - 8.8e-09 35.1 4.7 2e-08 33.9 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG11927.1 - 1.1e-07 31.6 3.3 2.4e-07 30.5 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEG11927.1 - 2.1e-07 31.1 7.0 2.1e-07 31.1 7.0 2.3 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEG11927.1 - 2.1e-07 30.6 4.5 5.2e-07 29.3 2.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KEG11927.1 - 7e-07 29.0 3.0 1.7e-06 27.8 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG11927.1 - 1.4e-06 28.2 2.7 1.4e-06 28.2 2.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KEG11927.1 - 7.8e-06 26.0 2.0 3.6e-05 23.8 2.1 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEG11927.1 - 3.5e-05 23.6 6.2 0.003 17.4 1.1 2.7 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KEG11927.1 - 0.00096 19.2 1.0 0.00096 19.2 1.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 KEG11927.1 - 0.002 18.0 1.3 0.1 12.5 0.1 2.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 KEG11927.1 - 0.0047 16.5 1.9 0.014 15.0 1.9 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FBP_C PF16571.5 KEG11927.1 - 0.037 13.6 0.9 0.065 12.8 0.9 1.4 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger FANCL_C PF11793.8 KEG11927.1 - 0.041 14.1 5.7 1.1 9.4 6.0 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain UBZ_FAAP20 PF15750.5 KEG11927.1 - 0.37 10.8 3.2 0.77 9.7 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-P11 PF03854.14 KEG11927.1 - 0.7 9.6 5.7 3.4 7.4 5.7 2.1 1 1 0 1 1 1 0 P-11 zinc finger Zn-C2H2_12 PF18112.1 KEG11927.1 - 5.3 7.6 7.6 5.3 7.6 0.1 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2722 PF10846.8 KEG11928.1 - 0.00011 21.3 0.9 0.00013 21.1 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 KEG11928.1 - 0.14 12.1 3.5 0.25 11.3 3.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 KEG11928.1 - 0.52 9.9 14.4 0.8 9.3 14.4 1.2 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 KEG11928.1 - 0.73 10.5 8.0 0.18 12.4 2.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3522 PF12036.8 KEG11930.1 - 3.7e-22 79.5 3.8 4.5e-22 79.2 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF1538 PF07556.11 KEG11930.1 - 0.0034 16.7 0.6 0.0083 15.4 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1538) CrgA PF06781.12 KEG11930.1 - 0.06 13.4 1.4 0.082 13.0 0.0 1.9 2 1 1 3 3 3 0 Cell division protein CrgA TctB PF07331.11 KEG11930.1 - 0.062 13.6 2.1 0.11 12.7 1.5 1.9 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family HlyIII PF03006.20 KEG11930.1 - 0.11 12.2 5.8 0.23 11.2 5.8 1.6 1 1 0 1 1 1 0 Haemolysin-III related Ceramidase PF05875.12 KEG11930.1 - 0.14 11.6 8.3 3.9 6.8 8.3 2.1 1 1 0 1 1 1 0 Ceramidase MFS_1 PF07690.16 KEG11930.1 - 0.15 10.9 3.9 0.18 10.7 3.9 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily PrgI PF12666.7 KEG11930.1 - 0.87 10.3 5.7 0.15 12.8 1.2 1.9 1 1 1 2 2 2 0 PrgI family protein DUF3522 PF12036.8 KEG11931.1 - 3.5e-44 151.4 10.7 4.1e-44 151.1 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Ceramidase PF05875.12 KEG11931.1 - 0.11 11.9 0.2 0.11 11.9 0.2 2.4 2 1 0 2 2 2 0 Ceramidase G0-G1_switch_2 PF15103.6 KEG11931.1 - 0.26 11.7 0.0 0.42 11.1 0.0 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Armet PF10208.9 KEG11932.1 - 0.0004 20.3 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding HhH-GPD PF00730.25 KEG11934.1 - 0.007 16.8 1.5 0.018 15.5 0.4 2.3 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein zf-rbx1 PF12678.7 KEG11934.1 - 0.094 13.0 2.4 0.13 12.6 0.8 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain RHSP PF07999.11 KEG11935.1 - 8.2e-95 318.2 0.1 1.5e-94 317.3 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon hot spot protein DEAD PF00270.29 KEG11936.1 - 3.7e-37 127.8 0.0 7.3e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG11936.1 - 6.6e-24 84.4 3.3 8.4e-24 84.1 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEG11936.1 - 3e-16 59.4 0.0 9.6e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEG11936.1 - 0.0079 16.2 0.0 0.0079 16.2 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DAG_kinase_N PF14513.6 KEG11936.1 - 0.49 10.6 4.0 1.9 8.7 0.4 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DnaJ PF00226.31 KEG11937.1 - 1.1e-17 63.9 0.2 2.6e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain RNase_H2_suC PF08615.11 KEG11937.1 - 0.077 13.2 0.3 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pkinase PF00069.25 KEG11939.1 - 1.6e-37 129.3 0.0 6.1e-37 127.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11939.1 - 1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG11939.1 - 1.9e-06 27.4 0.0 5.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Kinase-like TGS PF02824.21 KEG11939.1 - 0.0023 18.0 0.5 0.57 10.3 0.1 2.6 2 0 0 2 2 2 2 TGS domain APH PF01636.23 KEG11939.1 - 0.024 14.6 0.9 0.053 13.4 0.2 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEG11939.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_4 PF14570.6 KEG11939.1 - 0.28 11.0 14.1 0.56 10.0 14.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.17 KEG11940.1 - 1.3e-09 37.6 4.8 1.4e-09 37.4 0.1 2.8 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit TPR_2 PF07719.17 KEG11941.1 - 4.5e-12 45.1 0.7 0.062 13.4 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEG11941.1 - 7.8e-08 32.7 9.7 0.0017 18.8 0.2 4.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEG11941.1 - 2.2e-07 30.4 0.8 0.69 9.8 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG11941.1 - 2.4e-06 27.7 13.2 1.8 8.9 1.2 5.3 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEG11941.1 - 0.00018 21.7 4.0 11 6.7 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11941.1 - 0.00018 21.5 1.3 2.6 8.5 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG11941.1 - 0.00021 21.8 12.3 0.74 10.8 0.1 6.4 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEG11941.1 - 0.0015 17.8 2.6 0.5 9.5 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG11941.1 - 0.0064 16.1 3.2 5.9 6.7 0.0 5.4 7 0 0 7 7 7 1 TPR repeat TPR_7 PF13176.6 KEG11941.1 - 0.014 15.4 6.1 1.4 9.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG11941.1 - 0.049 14.3 10.4 0.057 14.1 0.4 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEG11941.1 - 0.11 13.2 0.9 68 4.5 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG11941.1 - 0.15 12.8 4.6 68 4.4 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SF3b10 PF07189.11 KEG11943.1 - 5.1e-12 45.7 0.0 5.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) LPD30 PF18850.1 KEG11944.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 HD_3 PF13023.6 KEG11945.1 - 9.8e-39 132.9 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KEG11945.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KEG11945.1 - 1.4e-05 25.3 0.0 3.2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 HD domain RRM_1 PF00076.22 KEG11948.1 - 8.6e-74 243.3 0.0 3e-17 62.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEG11948.1 - 2.6e-10 40.2 5.7 0.073 13.1 1.1 4.2 2 1 2 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.6 KEG11948.1 - 1.6e-07 31.2 0.5 0.07 13.1 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEG11948.1 - 5.4e-07 29.4 0.0 0.084 12.8 0.0 3.9 4 1 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM PF05172.13 KEG11948.1 - 2.1e-06 27.6 0.0 0.63 10.0 0.0 4.3 3 1 1 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEG11948.1 - 5.5e-06 26.4 0.9 5.1 7.3 0.0 5.0 4 3 0 4 4 4 3 RNA recognition motif Limkain-b1 PF11608.8 KEG11948.1 - 7.1e-05 22.8 1.1 1.4 9.0 0.0 4.7 4 2 1 5 5 5 2 Limkain b1 MinC_N PF05209.13 KEG11948.1 - 0.042 13.8 0.0 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain Guanylate_cyc PF00211.20 KEG11949.1 - 3.2e-45 154.0 0.0 5.5e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 KEG11949.1 - 3.3e-11 43.5 6.0 2.1e-07 30.9 2.0 2.7 2 1 0 2 2 2 2 Periplasmic binding protein B12-binding_2 PF02607.17 KEG11949.1 - 0.017 15.6 0.1 9.4 6.8 0.0 3.2 3 0 0 3 3 3 0 B12 binding domain ABC_sub_bind PF04392.12 KEG11949.1 - 0.18 11.0 0.1 4 6.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein PIGA PF08288.12 KEG11950.1 - 3.5e-35 120.4 0.1 6.4e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KEG11950.1 - 2.1e-29 102.7 0.3 4e-29 101.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEG11950.1 - 2.7e-26 92.2 0.0 3.9e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEG11950.1 - 1.1e-21 77.7 0.0 2.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEG11950.1 - 6.2e-16 59.2 0.5 1.1e-15 58.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KEG11950.1 - 1.1e-05 25.5 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KEG11950.1 - 0.0064 16.8 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 DNA_pol_B PF00136.21 KEG11952.1 - 8.4e-135 450.0 0.0 1.1e-134 449.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEG11952.1 - 1.2e-70 238.4 0.0 2e-70 237.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KEG11952.1 - 7.9e-17 61.5 7.6 2.2e-16 60.1 7.6 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KEG11952.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zinc-ribbons_6 PF07191.12 KEG11952.1 - 0.39 10.7 6.0 5.2 7.1 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbons SNF2_N PF00176.23 KEG11953.1 - 9.7e-71 238.3 1.2 2.9e-70 236.7 0.4 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG11953.1 - 5.7e-21 74.9 0.0 1.4e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLIDE PF09111.10 KEG11953.1 - 2.1e-09 37.4 0.3 5.7e-09 36.0 0.3 1.8 1 0 0 1 1 1 1 SLIDE ResIII PF04851.15 KEG11953.1 - 6.2e-08 32.8 0.1 1.1e-06 28.8 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG11953.1 - 1.1e-05 25.3 0.0 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase HAND PF09110.11 KEG11953.1 - 0.00022 22.0 10.6 0.00022 22.0 10.6 2.2 2 0 0 2 2 2 1 HAND HDA2-3 PF11496.8 KEG11953.1 - 0.0082 15.3 0.1 0.0082 15.3 0.1 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Caskin-Pro-rich PF16907.5 KEG11953.1 - 0.024 15.2 0.2 0.068 13.7 0.2 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins RRM_1 PF00076.22 KEG11953.1 - 0.05 13.4 0.1 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KEG11954.1 - 1e-65 221.7 0.0 1.7e-65 221.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11954.1 - 1.6e-36 126.0 0.0 2.4e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 KEG11954.1 - 8.4e-17 61.4 0.2 1.3e-09 38.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG11954.1 - 8.4e-13 47.1 1.5 0.055 13.4 0.0 5.6 4 1 2 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 KEG11954.1 - 6.9e-12 44.0 0.5 0.0072 15.8 0.0 5.5 4 2 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 KEG11954.1 - 4e-08 33.0 0.2 0.0061 16.4 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.6 KEG11954.1 - 1.2e-05 24.8 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEG11954.1 - 0.0004 19.8 0.1 0.00088 18.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEG11954.1 - 0.0036 16.9 0.1 0.0079 15.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family SPARC_Ca_bdg PF10591.9 KEG11954.1 - 0.01 16.2 1.2 0.34 11.3 0.1 2.8 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Haspin_kinase PF12330.8 KEG11954.1 - 0.013 14.5 0.1 0.023 13.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain EF-hand_5 PF13202.6 KEG11954.1 - 0.025 14.1 3.0 2 8.1 0.1 3.8 4 0 0 4 4 4 0 EF hand PMBR PF09373.10 KEG11954.1 - 0.096 12.9 0.0 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Pseudomurein-binding repeat APH PF01636.23 KEG11954.1 - 0.18 11.7 0.1 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family TPR_12 PF13424.6 KEG11955.1 - 1.3e-21 76.6 15.8 8.5e-11 42.0 2.5 3.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEG11955.1 - 3.6e-11 42.3 13.2 0.11 12.7 0.3 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEG11955.1 - 6.8e-11 41.5 10.3 0.087 12.7 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEG11955.1 - 5.5e-08 32.4 4.9 0.011 15.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG11955.1 - 3.4e-06 26.7 11.7 0.18 11.9 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEG11955.1 - 0.00034 20.1 6.7 0.00041 19.8 3.5 2.0 2 0 0 2 2 2 1 MalT-like TPR region RPN7 PF10602.9 KEG11955.1 - 0.00069 19.4 0.6 2.9 7.6 0.0 3.2 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_9 PF13371.6 KEG11955.1 - 0.0013 18.9 1.6 0.025 14.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG11955.1 - 0.0048 17.5 7.2 6.1 7.6 0.3 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.9 KEG11955.1 - 0.027 14.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 KEG11955.1 - 0.13 12.2 6.3 17 5.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG11955.1 - 0.25 12.2 5.3 30 5.8 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEG11955.1 - 1.2 9.9 5.7 21 6.1 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG11955.1 - 3.2 8.6 8.5 1.9 9.3 0.1 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_assoc PF14363.6 KEG11956.1 - 0.044 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Autophagy_N PF03986.13 KEG11957.1 - 2.7e-32 111.6 1.2 4.6e-32 110.8 1.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KEG11957.1 - 4.3e-15 56.0 0.3 8.2e-15 55.1 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KEG11957.1 - 1.9e-11 43.3 0.9 3.9e-11 42.3 0.9 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SDA1 PF05285.12 KEG11957.1 - 0.021 14.2 3.7 0.03 13.8 3.7 1.3 1 0 0 1 1 1 0 SDA1 TP_methylase PF00590.20 KEG11958.1 - 0.03 14.2 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases CHAT PF12770.7 KEG11959.1 - 2e-39 135.8 0.7 4e-39 134.8 0.7 1.5 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.6 KEG11959.1 - 0.00055 19.8 0.3 1.3 9.3 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat DUF4807 PF16065.5 KEG11959.1 - 0.0051 16.5 0.3 0.021 14.5 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4807) Glyco_hydro_17 PF00332.18 KEG11959.1 - 0.018 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 RskA PF10099.9 KEG11959.1 - 2.7 8.2 25.4 2 8.7 4.3 4.7 3 1 0 4 4 4 0 Anti-sigma-K factor rskA BioT2 PF15368.6 KEG11960.1 - 0.08 12.9 1.1 0.15 12.0 1.1 1.4 1 0 0 1 1 1 0 Spermatogenesis family BioT2 SesA PF17107.5 KEG11960.1 - 0.12 12.6 0.4 0.12 12.6 0.4 2.2 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Mer2 PF09074.10 KEG11960.1 - 0.13 12.1 3.1 0.095 12.5 1.2 1.7 1 1 1 2 2 2 0 Mer2 Cytochrom_B562 PF07361.11 KEG11960.1 - 2.1 9.0 13.9 12 6.7 5.7 3.3 2 1 1 3 3 3 0 Cytochrome b562 Ribosomal_60s PF00428.19 KEG11960.1 - 3.1 8.4 7.0 25 5.5 0.1 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein L31 PF09784.9 KEG11960.1 - 3.8 8.0 7.5 0.94 9.9 1.1 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 LPD34 PF18852.1 KEG11960.1 - 3.8 7.0 12.9 0.22 11.1 3.8 2.5 1 1 1 3 3 3 0 Large polyvalent protein associated domain 34 RNase_E_G PF10150.9 KEG11960.1 - 7.4 5.9 11.3 17 4.8 11.3 1.5 1 1 0 1 1 1 0 Ribonuclease E/G family LRR_6 PF13516.6 KEG11962.1 - 1.9e-18 64.8 24.6 0.001 19.0 0.1 10.5 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 KEG11962.1 - 1.6e-11 44.2 17.0 0.85 10.1 0.0 9.8 6 3 5 12 12 12 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG11962.1 - 4.2e-07 29.6 22.1 0.27 11.0 0.2 10.8 6 4 2 8 8 8 3 Leucine rich repeat DAP10 PF07213.11 KEG11962.1 - 0.067 13.2 4.1 12 6.0 3.0 3.0 2 0 0 2 2 2 0 DAP10 membrane protein LRR_1 PF00560.33 KEG11962.1 - 0.068 13.7 27.4 18 6.4 0.1 10.5 12 2 0 12 12 12 0 Leucine Rich Repeat Glycolipid_bind PF06475.11 KEG11962.1 - 0.094 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative glycolipid-binding Pkinase PF00069.25 KEG11963.1 - 3.6e-36 124.9 0.0 5.4e-36 124.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11963.1 - 2e-13 50.3 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEG11965.1 - 9.8e-53 179.2 0.0 1.5e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG11965.1 - 2.7e-34 118.7 0.0 4.3e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Guanylate_cyc PF00211.20 KEG11965.1 - 3.9e-05 23.4 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kdo PF06293.14 KEG11965.1 - 0.004 16.5 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG11965.1 - 0.0087 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEG11965.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KEG11965.1 - 0.13 11.6 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Kinase-like PRIMA1 PF16101.5 KEG11965.1 - 0.32 11.0 1.2 1.2 9.2 0.9 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MnhB PF04039.13 KEG11967.1 - 0.043 14.1 0.1 0.085 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter EphA2_TM PF14575.6 KEG11967.1 - 0.061 14.2 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TrbL PF04610.14 KEG11967.1 - 0.11 12.3 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Aa_trans PF01490.18 KEG11970.1 - 2.1e-45 155.2 30.1 6.3e-45 153.6 30.1 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PET117 PF15786.5 KEG11971.1 - 0.051 13.8 1.3 0.27 11.5 0.0 2.2 2 1 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial PAP_assoc PF03828.19 KEG11972.1 - 8.3e-08 32.3 0.3 1.8e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KEG11972.1 - 0.024 14.7 0.1 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KEG11972.1 - 0.094 13.0 0.1 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase domain DKCLD PF08068.12 KEG11973.1 - 4.3e-32 110.0 0.2 8.3e-30 102.6 0.1 2.5 2 0 0 2 2 2 2 DKCLD (NUC011) domain TruB_N PF01509.18 KEG11973.1 - 3e-22 79.6 1.4 9.4e-19 68.2 1.4 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KEG11973.1 - 9.6e-21 73.7 0.2 1.8e-20 72.8 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KEG11973.1 - 1.5e-19 69.7 0.6 4e-19 68.4 0.4 1.8 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 KEG11973.1 - 0.0028 17.9 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain ATP-synt PF00231.19 KEG11974.1 - 4.3e-46 157.9 4.9 4.8e-46 157.7 4.9 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.19 KEG11975.1 - 6.4e-40 136.0 0.0 6.4e-40 136.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e ATP-synt_C PF00137.21 KEG11976.1 - 3.4e-27 94.6 42.6 1.3e-19 70.3 15.2 3.0 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 KEG11976.1 - 0.38 9.2 4.3 2.8 6.3 0.9 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Gaa1 PF04114.14 KEG11977.1 - 1.7e-07 30.7 0.4 1.7e-07 30.7 0.4 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.19 KEG11978.1 - 3.9e-36 123.0 4.1 4.4e-36 122.8 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 KEG11978.1 - 0.0026 17.6 2.0 0.0037 17.1 2.0 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 KEG11978.1 - 0.047 13.8 1.0 0.063 13.4 1.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KEG11978.1 - 0.062 13.3 2.6 0.1 12.6 2.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 KEG11978.1 - 0.18 12.0 3.3 0.6 10.3 0.4 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-HIT PF04438.16 KEG11978.1 - 0.22 11.4 2.4 0.31 11.0 0.5 1.9 2 0 0 2 2 2 0 HIT zinc finger Proteasome PF00227.26 KEG11979.1 - 2.3e-57 193.5 0.0 2.9e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG11979.1 - 1.3e-13 50.4 0.0 4e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2866 PF11065.8 KEG11979.1 - 0.072 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Pex14_N PF04695.13 KEG11980.1 - 1.5e-22 81.0 0.2 1.5e-22 81.0 0.2 2.7 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region betaPIX_CC PF16523.5 KEG11980.1 - 0.0027 17.5 2.2 0.0081 16.0 2.2 1.8 1 0 0 1 1 1 1 betaPIX coiled coil CENP-H PF05837.12 KEG11980.1 - 0.011 16.1 5.3 0.023 15.1 5.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4404 PF14357.6 KEG11980.1 - 0.03 15.0 2.0 0.03 15.0 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Atg14 PF10186.9 KEG11980.1 - 0.058 12.5 3.0 0.089 11.9 3.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HemX PF04375.14 KEG11980.1 - 0.15 11.3 7.9 0.23 10.7 7.9 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATG16 PF08614.11 KEG11980.1 - 0.21 11.8 10.5 0.34 11.1 10.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 KEG11980.1 - 0.4 11.3 7.7 0.78 10.4 7.7 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 ADIP PF11559.8 KEG11980.1 - 3.4 7.7 11.3 6 6.9 10.4 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BolA PF01722.18 KEG11982.1 - 4e-16 59.1 0.1 1.1e-15 57.6 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein Ribosomal_L32e PF01655.18 KEG11984.1 - 7.9e-42 142.1 0.4 9.2e-42 141.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CdiI PF07262.11 KEG11984.1 - 0.049 13.4 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 CDI immunity protein SH3_9 PF14604.6 KEG11985.1 - 2.6e-32 110.4 0.9 1.8e-12 46.9 0.0 3.7 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 KEG11985.1 - 3e-32 110.0 0.0 1.2e-11 44.0 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KEG11985.1 - 4.3e-29 100.0 0.3 2.9e-11 42.9 0.1 3.2 3 0 0 3 3 3 3 Variant SH3 domain DUF4205 PF13898.6 KEG11986.1 - 3.9e-22 78.7 0.0 7.4e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) DUF4636 PF15468.6 KEG11986.1 - 0.16 11.6 2.7 0.29 10.8 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) NIF PF03031.18 KEG11987.1 - 3e-32 111.6 0.0 5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KEG11987.1 - 0.0015 19.0 0.1 0.0042 17.5 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RMF PF04957.12 KEG11987.1 - 0.046 13.9 0.4 0.43 10.8 0.2 2.4 2 0 0 2 2 2 0 Ribosome modulation factor YscO PF07321.12 KEG11988.1 - 6.5e-08 32.7 26.7 6.5e-08 32.7 26.7 20.2 13 6 4 20 20 20 2 Type III secretion protein YscO GAS PF13851.6 KEG11988.1 - 0.00096 18.6 3.7 0.00096 18.6 3.7 19.1 13 7 3 18 18 18 5 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KEG11988.1 - 0.006 16.7 3.1 0.006 16.7 3.1 23.1 14 8 11 25 25 25 6 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KEG11988.1 - 0.035 14.5 0.2 0.035 14.5 0.2 27.3 18 9 6 24 24 24 0 Cell division protein ZapB DUF3800 PF12686.7 KEG11988.1 - 0.22 12.1 3.4 2.9e+02 2.1 0.0 6.0 3 2 0 3 3 3 0 Protein of unknown function (DUF3800) bZIP_1 PF00170.21 KEG11988.1 - 0.41 10.8 0.0 0.38 10.9 0.2 19.6 20 1 0 20 20 20 0 bZIP transcription factor UBM PF14377.6 KEG11988.1 - 1 8.9 12.7 1 8.9 0.3 4.1 3 0 0 3 3 3 0 Ubiquitin binding region zf-RING_2 PF13639.6 KEG11989.1 - 2.3e-12 47.0 10.2 3.6e-12 46.4 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG11989.1 - 1.3e-09 37.8 10.6 2e-09 37.1 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEG11989.1 - 1.7e-09 37.8 8.1 3.4e-09 36.8 8.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEG11989.1 - 1.4e-08 34.3 4.7 2.4e-08 33.6 4.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KEG11989.1 - 3.8e-07 30.0 6.5 7.7e-07 29.0 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG11989.1 - 5.7e-07 29.3 10.9 9e-07 28.7 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG11989.1 - 3.1e-06 27.0 9.0 4.5e-06 26.4 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG11989.1 - 1.8e-05 24.7 2.0 3.5e-05 23.8 2.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KEG11989.1 - 3.9e-05 23.5 9.0 6.2e-05 22.9 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KEG11989.1 - 0.0012 18.4 6.9 0.002 17.7 6.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KEG11989.1 - 0.0044 16.8 7.5 0.0074 16.1 7.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KEG11989.1 - 0.063 13.2 6.7 0.12 12.2 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 KEG11989.1 - 0.13 12.1 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 KEG11989.1 - 0.24 11.6 6.3 0.56 10.4 6.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KEG11989.1 - 0.26 11.2 7.8 0.53 10.2 7.8 1.6 1 1 0 1 1 1 0 PHD-finger S6OS1 PF15676.5 KEG11989.1 - 0.32 9.4 3.1 0.45 8.9 3.1 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family zf-RING-like PF08746.11 KEG11989.1 - 0.36 11.2 9.6 0.57 10.5 9.6 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KEG11989.1 - 0.54 10.4 10.5 0.93 9.7 10.5 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KEG11989.1 - 1.7 8.6 8.7 9.2 6.3 8.9 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KEG11989.1 - 2.1 8.6 6.3 1.6 8.9 4.3 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain DUF1242 PF06842.12 KEG11990.1 - 6.4e-11 41.9 0.2 1e-10 41.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.31 KEG11992.1 - 8.1e-08 32.3 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.24 KEG11992.1 - 5.8 7.0 7.9 0.39 10.7 3.0 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L7Ae PF01248.26 KEG11993.1 - 2.2e-24 85.0 0.0 2.5e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ArfGap PF01412.18 KEG11995.1 - 2.4e-23 82.4 0.4 7.7e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PMG PF05287.12 KEG11996.1 - 0.061 13.4 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 PMG protein Lamprin PF06403.11 KEG11996.1 - 0.097 12.6 58.2 0.02 14.9 18.0 3.1 1 1 2 3 3 3 0 Lamprin Herpes_UL36 PF03586.13 KEG11996.1 - 0.12 11.6 0.9 0.16 11.2 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Eisosome1 PF12757.7 KEG11997.1 - 0.48 10.7 9.8 28 5.0 9.6 2.1 1 1 0 1 1 1 0 Eisosome protein 1 Coq4 PF05019.13 KEG11998.1 - 1.8e-61 207.3 0.0 2.2e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TF_Zn_Ribbon PF08271.12 KEG11998.1 - 0.0041 16.6 0.0 0.01 15.3 0.1 1.6 2 0 0 2 2 2 1 TFIIB zinc-binding DUF1289 PF06945.13 KEG11998.1 - 0.064 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DnaJ PF00226.31 KEG12000.1 - 4.8e-11 42.6 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain UCH_C PF18031.1 KEG12000.1 - 4 7.4 5.6 9.1 6.3 5.6 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Rhodanese PF00581.20 KEG12001.1 - 9.2e-11 42.2 0.0 1.2e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RcsC PF09456.10 KEG12001.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Rhodanese PF00581.20 KEG12002.1 - 7.1e-11 42.6 0.0 9.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 KEG12003.1 - 8e-14 52.1 0.0 8.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DB_JBP1 PF18526.1 KEG12004.1 - 8.8e-81 269.7 4.8 8.8e-81 269.7 4.8 1.8 2 0 0 2 2 2 1 Thymine dioxygenase JBP1 DNA-binding domain Tet_JBP PF12851.7 KEG12004.1 - 2.5e-26 92.8 0.0 1.7e-20 73.7 0.0 2.6 2 1 1 3 3 3 2 Oxygenase domain of the 2OGFeDO superfamily Rsm22 PF09243.10 KEG12004.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Cyt-b5 PF00173.28 KEG12005.1 - 1.2e-20 73.4 0.1 1.5e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IQ PF00612.27 KEG12007.1 - 0.021 14.6 1.5 0.087 12.7 1.5 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif LRR_6 PF13516.6 KEG12008.1 - 2.3e-17 61.5 0.2 0.015 15.3 0.0 6.7 6 0 0 6 6 6 5 Leucine Rich repeat DDDD PF10161.9 KEG12008.1 - 0.0024 17.6 0.0 0.0074 16.0 0.0 1.7 2 0 0 2 2 2 1 Putative mitochondrial precursor protein EF-hand_7 PF13499.6 KEG12009.1 - 1.8e-09 37.9 0.2 3.6e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG12009.1 - 7.5e-09 34.8 1.0 0.0025 17.6 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEG12009.1 - 4.8e-08 32.0 4.2 0.0029 17.1 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KEG12009.1 - 4.5e-06 26.4 1.5 0.0013 18.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KEG12009.1 - 6.7e-06 25.4 4.8 0.0088 15.5 0.1 3.1 3 0 0 3 3 3 2 EF hand RIIa PF02197.17 KEG12009.1 - 5.1e-05 22.8 1.0 0.0016 18.1 0.0 2.7 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit Dockerin_1 PF00404.18 KEG12009.1 - 0.11 12.7 0.1 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Dockerin type I domain TPT PF03151.16 KEG12010.1 - 2.3e-08 33.8 22.3 2.7e-08 33.5 22.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEG12010.1 - 6.8e-08 32.8 34.2 2.7e-06 27.6 14.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family Seryl_tRNA_N PF02403.22 KEG12011.1 - 0.008 16.4 8.4 0.008 16.4 8.4 8.4 2 2 6 9 9 9 4 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 KEG12011.1 - 0.044 13.6 114.0 0.016 15.0 28.8 7.2 2 2 4 6 6 6 0 Coiled-coil region of CCDC155 or KASH Tup_N PF08581.10 KEG12011.1 - 0.16 12.3 0.1 0.16 12.3 0.1 8.3 7 1 5 12 12 12 0 Tup N-terminal DUF4686 PF15742.5 KEG12011.1 - 7.8 5.5 109.9 0.068 12.3 21.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Bravo_FIGEY PF13882.6 KEG12012.1 - 0.059 14.7 0.8 0.2 13.1 0.1 2.0 2 0 0 2 2 2 0 Bravo-like intracellular region FAM176 PF14851.6 KEG12012.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 FAM176 family TPT PF03151.16 KEG12013.1 - 1.2e-07 31.4 7.8 1.2e-07 31.4 7.8 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KEG12013.1 - 0.00043 20.5 25.3 0.0015 18.7 7.1 3.3 2 1 0 3 3 3 2 EamA-like transporter family HyaE PF07449.11 KEG12014.1 - 0.11 12.4 0.1 2.6 8.1 0.0 2.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Spt20 PF12090.8 KEG12014.1 - 0.31 10.6 1.3 0.65 9.6 1.3 1.4 1 0 0 1 1 1 0 Spt20 family Cyt_bd_oxida_II PF02322.15 KEG12014.1 - 0.37 10.1 2.5 0.71 9.2 2.5 1.4 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II MutS_III PF05192.18 KEG12014.1 - 0.81 9.9 4.2 39 4.4 0.5 3.8 3 2 0 3 3 3 0 MutS domain III NIF PF03031.18 KEG12015.1 - 8.8e-29 100.3 0.0 6.6e-28 97.4 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase VP40 PF07447.12 KEG12015.1 - 0.035 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Matrix protein VP40 Brix PF04427.18 KEG12016.1 - 3.2e-35 122.0 0.0 4.5e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pyrophosphatase PF00719.19 KEG12017.1 - 8.7e-37 126.4 0.0 1e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pep_M12B_propep PF01562.19 KEG12017.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide Got1 PF04178.12 KEG12018.1 - 2.6e-29 101.9 16.4 3.7e-29 101.4 16.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Spec3 PF15795.5 KEG12018.1 - 3.3 8.3 12.4 27 5.4 9.3 2.6 2 1 0 2 2 2 0 Ectodermal ciliogenesis protein zf-LYAR PF08790.11 KEG12019.1 - 1.4e-13 50.5 3.9 1.4e-13 50.5 3.9 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DpnI PF06044.12 KEG12019.1 - 0.12 12.0 0.7 0.2 11.3 0.7 1.3 1 0 0 1 1 1 0 Dam-replacing family DM PF00751.18 KEG12019.1 - 0.15 12.0 0.8 0.34 10.9 0.8 1.6 1 0 0 1 1 1 0 DM DNA binding domain Herpes_DNAp_acc PF04929.12 KEG12019.1 - 0.19 10.7 5.5 0.26 10.2 5.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RRM_1 PF00076.22 KEG12020.1 - 9.3e-36 121.5 0.0 5e-12 45.5 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG12020.1 - 0.0022 17.6 0.0 0.013 15.1 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG12020.1 - 0.0086 16.2 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_1 PF00076.22 KEG12022.1 - 3.5e-31 106.8 0.0 9.9e-20 70.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG12022.1 - 9e-06 25.3 0.0 0.00039 20.0 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KEG12022.1 - 0.00033 20.6 0.0 0.019 15.0 0.0 2.6 2 1 0 2 2 2 1 RNA binding domain Nup35_RRM_2 PF14605.6 KEG12022.1 - 0.0062 16.5 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEG12022.1 - 0.024 14.7 0.0 0.83 9.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF4701 PF15773.5 KEG12022.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) GAS PF13851.6 KEG12023.1 - 1.3 8.3 10.8 4.7 6.5 9.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding tRNA-synt_2c PF01411.19 KEG12024.1 - 4e-194 646.2 0.0 5.3e-194 645.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KEG12024.1 - 7.6e-10 38.7 0.0 2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KEG12024.1 - 0.00036 21.0 5.6 0.0028 18.1 6.1 2.3 2 0 0 2 2 2 1 DHHA1 domain CoaE PF01121.20 KEG12025.1 - 1.5e-43 148.5 0.0 4.2e-43 147.1 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KEG12025.1 - 0.00033 21.2 0.1 0.011 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEG12025.1 - 0.00065 20.1 0.0 0.0058 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEG12025.1 - 0.00074 19.7 0.2 0.0029 17.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KEG12025.1 - 0.0095 16.1 0.0 0.022 14.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase PRK PF00485.18 KEG12025.1 - 0.029 14.1 0.6 0.31 10.8 0.0 2.4 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.6 KEG12025.1 - 0.13 12.4 0.3 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Ribosomal_L14e PF01929.17 KEG12026.1 - 1.4e-15 57.5 3.4 1.4e-15 57.5 3.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 KEG12026.1 - 2.3e-05 24.1 0.5 3.8e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 KOW motif ASH PF15780.5 KEG12027.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HA2 PF04408.23 KEG12029.1 - 1.5e-17 63.8 0.0 1.5e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEG12029.1 - 2.1e-12 47.4 0.0 5.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.22 KEG12029.1 - 3.5e-09 36.5 0.0 1.1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 KEG12029.1 - 2.6e-07 30.6 0.1 5.4e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KEG12029.1 - 0.0049 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KEG12029.1 - 0.015 15.6 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEG12029.1 - 0.036 14.4 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 KEG12030.1 - 3.2e-11 44.1 0.5 5.8e-11 43.3 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tektin PF03148.14 KEG12033.1 - 0.015 14.1 4.8 0.019 13.7 4.8 1.2 1 0 0 1 1 1 0 Tektin family Cytadhesin_P30 PF07271.11 KEG12033.1 - 0.089 12.3 0.9 0.11 12.1 0.9 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 bZIP_2 PF07716.15 KEG12033.1 - 0.42 10.7 3.9 1 9.5 1.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF3450 PF11932.8 KEG12033.1 - 1.3 8.3 9.1 1.7 7.9 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KEG12033.1 - 7 7.2 10.6 0.95 9.9 5.3 1.9 1 1 1 2 2 2 0 Cell division protein ZapB T2SSI PF02501.17 KEG12034.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Hist_deacetyl PF00850.19 KEG12035.1 - 4.1e-71 240.0 0.0 5.2e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_1 PF00036.32 KEG12036.1 - 1.3e-19 68.2 5.1 5e-07 28.8 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KEG12036.1 - 3.1e-19 69.2 7.3 5.3e-09 36.4 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG12036.1 - 4.9e-18 63.4 1.7 0.00035 20.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEG12036.1 - 2.2e-15 55.4 3.6 0.001 18.5 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KEG12036.1 - 3e-14 52.6 4.8 0.0011 18.8 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain pair zf-C3HC4_3 PF13920.6 KEG12036.1 - 1.3e-09 37.7 7.0 2.8e-09 36.7 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG12036.1 - 1.6e-08 34.3 8.2 3.5e-08 33.2 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEG12036.1 - 2.9e-08 33.4 9.2 2.9e-08 33.4 9.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG12036.1 - 2.2e-07 30.7 6.8 2.2e-07 30.7 6.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG12036.1 - 5.1e-07 29.5 5.2 5.1e-07 29.5 5.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG12036.1 - 1.3e-06 28.6 9.0 1.3e-06 28.6 9.0 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KEG12036.1 - 7.6e-06 25.8 8.6 7.6e-06 25.8 8.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KEG12036.1 - 1.1e-05 25.2 4.6 2e-05 24.4 4.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SPARC_Ca_bdg PF10591.9 KEG12036.1 - 9.5e-05 22.7 0.0 0.35 11.2 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 KEG12036.1 - 0.00011 23.0 0.1 0.43 11.5 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain zf-C3HC4_4 PF15227.6 KEG12036.1 - 0.00086 19.4 5.8 0.00086 19.4 5.8 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KEG12036.1 - 0.041 13.6 4.1 0.12 12.1 4.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger Lar_restr_allev PF14354.6 KEG12036.1 - 0.1 13.0 0.7 0.1 13.0 0.7 2.0 2 0 0 2 2 1 0 Restriction alleviation protein Lar EF-hand_9 PF14658.6 KEG12036.1 - 0.12 12.8 0.1 21 5.5 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain zf-rbx1 PF12678.7 KEG12036.1 - 1.1 9.6 7.9 3.7 7.9 7.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mlh1_C PF16413.5 KEG12037.1 - 1.8e-43 148.8 0.0 3.4e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KEG12037.1 - 5.6e-25 87.3 0.0 1.1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KEG12037.1 - 1.7e-09 37.6 0.0 3.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEG12037.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIF_alpha PF05793.12 KEG12037.1 - 0.38 9.3 2.0 0.52 8.8 2.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Kinesin PF00225.23 KEG12038.1 - 3.9e-58 197.0 0.0 3.8e-40 137.8 0.0 2.9 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KEG12038.1 - 8.7e-12 45.2 0.1 4e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding UPF0184 PF03670.13 KEG12038.1 - 0.02 15.3 0.2 0.44 11.0 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) T2SSE PF00437.20 KEG12038.1 - 0.084 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PH PF00169.29 KEG12039.1 - 9e-16 58.3 0.1 1.8e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 PH domain HpcH_HpaI PF03328.14 KEG12041.1 - 1.1e-07 31.2 0.0 0.001 18.3 0.0 2.8 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEG12041.1 - 0.0018 17.5 0.0 0.0081 15.3 0.0 1.8 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold SDH_sah PF01972.16 KEG12041.1 - 0.099 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Pkinase PF00069.25 KEG12042.1 - 1e-62 211.9 0.0 1.3e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12042.1 - 1.7e-38 132.4 0.0 2.4e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG12042.1 - 9.2e-06 24.7 0.1 1.9e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase DZR PF12773.7 KEG12042.1 - 0.00065 19.7 1.1 0.0013 18.7 1.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KEG12042.1 - 0.00079 19.1 6.1 0.0018 17.9 6.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain APH PF01636.23 KEG12042.1 - 0.001 19.0 0.0 0.026 14.5 0.0 2.5 1 1 2 3 3 3 1 Phosphotransferase enzyme family zf-ribbon_3 PF13248.6 KEG12042.1 - 0.018 14.4 3.0 0.042 13.3 3.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Kdo PF06293.14 KEG12042.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-NADH-PPase PF09297.11 KEG12042.1 - 0.026 14.2 2.5 0.57 9.9 0.3 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 KEG12042.1 - 0.098 12.8 3.6 0.26 11.5 3.6 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like ADK_lid PF05191.14 KEG12042.1 - 0.11 12.5 2.3 0.28 11.2 2.3 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid UPF0547 PF10571.9 KEG12042.1 - 0.25 11.5 2.5 12 6.1 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.10 KEG12042.1 - 0.49 10.2 4.0 0.65 9.8 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Cript PF10235.9 KEG12042.1 - 1 10.0 5.2 0.25 11.9 1.5 1.9 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-RanBP PF00641.18 KEG12042.1 - 1.3 8.4 5.5 2.7 7.4 5.5 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Nudix_N_2 PF14803.6 KEG12042.1 - 2.1 8.3 6.1 3.1 7.8 1.2 2.6 2 0 0 2 2 2 0 Nudix N-terminal AMP-binding PF00501.28 KEG12048.1 - 3.4e-83 279.6 0.2 3.3e-81 273.1 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEG12048.1 - 4e-15 55.5 2.3 5.3e-15 55.1 0.6 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus OrfB_Zn_ribbon PF07282.11 KEG12049.1 - 0.075 13.0 2.0 0.19 11.6 2.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain XRN_N PF03159.18 KEG12050.1 - 1.9e-51 174.8 0.0 7.6e-50 169.6 0.0 2.2 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KEG12050.1 - 2.3e-05 23.6 0.1 2.3e-05 23.6 0.1 2.6 3 0 0 3 3 3 1 Xrn1 helical domain DUF1192 PF06698.11 KEG12051.1 - 0.79 9.8 7.4 0.49 10.5 3.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) GFO_IDH_MocA PF01408.22 KEG12052.1 - 1.4e-12 48.5 0.0 3.5e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.9 KEG12052.1 - 0.0075 16.1 0.4 0.022 14.6 0.1 1.9 2 0 0 2 2 2 1 Rossmann-like domain GFO_IDH_MocA PF01408.22 KEG12053.1 - 1.6e-08 35.4 0.0 3.4e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold PBP1_TM PF14812.6 KEG12055.1 - 0.73 10.2 5.2 1.7 9.1 5.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WW PF00397.26 KEG12056.1 - 1.5e-29 101.7 19.1 4.8e-10 39.4 0.7 3.5 3 0 0 3 3 3 3 WW domain DUF4585 PF15232.6 KEG12056.1 - 0.033 14.2 0.0 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) Hydrolase_2 PF07486.12 KEG12056.1 - 0.15 12.9 8.8 1.7 9.5 1.5 3.4 1 1 2 3 3 3 0 Cell Wall Hydrolase DUF2690 PF10901.8 KEG12056.1 - 0.79 10.1 3.6 29 5.0 0.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2690) Glyco_hyd_101C PF17451.2 KEG12056.1 - 1.6 9.1 11.3 5.8 7.2 0.7 3.5 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain TAP42 PF04177.12 KEG12058.1 - 6.6e-53 179.9 2.8 7.4e-53 179.7 2.8 1.0 1 0 0 1 1 1 1 TAP42-like family ATP_bind_1 PF03029.17 KEG12060.1 - 1.7e-62 211.4 0.0 1.9e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KEG12060.1 - 0.00036 20.3 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG12060.1 - 0.00036 20.9 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KEG12060.1 - 0.0008 20.0 0.2 0.0019 18.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEG12060.1 - 0.0011 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KEG12060.1 - 0.0032 17.3 0.0 0.0069 16.2 0.0 1.5 2 0 0 2 2 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 KEG12060.1 - 0.0052 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KEG12060.1 - 0.0058 16.7 0.0 0.042 13.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 KEG12060.1 - 0.0069 16.0 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KEG12060.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KEG12060.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Cytidylate_kin PF02224.18 KEG12060.1 - 0.0097 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_14 PF13173.6 KEG12060.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KEG12060.1 - 0.026 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEG12060.1 - 0.027 14.9 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 KEG12060.1 - 0.036 14.5 0.1 0.094 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEG12060.1 - 0.042 13.6 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KEG12060.1 - 0.046 13.6 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KEG12060.1 - 0.049 13.8 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEG12060.1 - 0.065 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEG12060.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KEG12060.1 - 0.084 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 KEG12060.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KEG12060.1 - 0.11 12.3 0.0 0.93 9.2 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KEG12060.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEG12060.1 - 0.12 11.5 0.3 0.21 10.7 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 KEG12060.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 KEG12060.1 - 0.13 11.2 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KEG12060.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KEG12060.1 - 0.15 11.9 0.2 0.43 10.5 0.1 1.7 2 0 0 2 2 2 0 NTPase RsgA_GTPase PF03193.16 KEG12060.1 - 0.16 11.9 0.0 0.98 9.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 KEG12060.1 - 0.17 11.9 0.0 0.18 11.9 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 KEG12060.1 - 0.19 10.8 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 KEG12060.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 KEG12060.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase Surp PF01805.20 KEG12061.1 - 1.3e-11 44.3 7.7 7e-10 38.8 0.9 2.3 2 0 0 2 2 2 2 Surp module Dicty_REP PF05086.12 KEG12061.1 - 7.9 4.3 11.3 0.51 8.3 0.1 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DNA_pol_D_N PF18018.1 KEG12062.1 - 2.6e-31 108.4 0.0 4.3e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KEG12062.1 - 8.6e-27 93.9 0.0 2.7e-26 92.2 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ras PF00071.22 KEG12063.1 - 6.4e-50 168.9 0.0 7.8e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG12063.1 - 1.6e-31 109.0 0.0 2.7e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG12063.1 - 2.7e-10 40.0 0.0 3.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG12063.1 - 0.00024 20.5 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG12063.1 - 0.00051 20.1 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KEG12063.1 - 0.0013 19.1 0.2 0.0084 16.5 0.2 2.1 1 1 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 KEG12063.1 - 0.014 15.3 0.1 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KEG12063.1 - 0.027 13.6 1.3 0.95 8.6 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit GTP_EFTU PF00009.27 KEG12063.1 - 0.032 13.8 0.5 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KEG12063.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KEG12063.1 - 0.046 13.2 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.6 KEG12063.1 - 0.051 13.7 0.3 0.064 13.4 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEG12063.1 - 0.08 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KEG12063.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KEG12063.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KEG12063.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain FluMu_N PF17891.1 KEG12063.1 - 1.8 8.4 4.0 19 5.1 0.4 3.2 3 0 0 3 3 3 0 Mu-like prophage FluMu N-terminal domain Cluap1 PF10234.9 KEG12064.1 - 8.5e-92 307.3 8.3 1.3e-91 306.8 8.3 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 KEG12064.1 - 0.014 13.9 1.4 0.021 13.3 1.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like LPP PF04728.13 KEG12064.1 - 0.027 14.9 1.0 0.13 12.6 1.0 2.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KEG12064.1 - 0.053 13.6 0.5 0.13 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MutS_II PF05188.17 KEG12064.1 - 0.11 12.8 1.8 0.24 11.7 1.8 1.6 1 0 0 1 1 1 0 MutS domain II Csm1_N PF18504.1 KEG12064.1 - 0.6 10.5 6.5 0.22 11.9 1.6 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain COG2 PF06148.11 KEG12064.1 - 0.68 10.0 9.6 0.15 12.2 4.4 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tup_N PF08581.10 KEG12064.1 - 0.9 9.9 8.6 0.068 13.5 2.2 2.4 1 1 1 2 2 2 0 Tup N-terminal Snapin_Pallidin PF14712.6 KEG12064.1 - 1.4 9.4 7.0 0.38 11.2 1.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Atg14 PF10186.9 KEG12064.1 - 2.8 7.0 7.3 4.9 6.1 7.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KEG12064.1 - 3.3 7.0 10.8 0.41 9.9 6.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KEG12064.1 - 4.9 7.4 7.4 3.3 8.0 1.3 2.7 2 0 0 2 2 2 0 Haemolysin XhlA SseC PF04888.12 KEG12064.1 - 7.4 6.1 12.3 0.33 10.5 6.5 1.6 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family RNase_T PF00929.24 KEG12065.1 - 3.8e-09 37.3 0.0 5.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease NYD-SP28_assoc PF14775.6 KEG12065.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain SPT_ssu-like PF11779.8 KEG12067.1 - 0.00073 19.1 1.4 0.0016 18.0 1.4 1.5 1 1 1 2 2 2 1 Small subunit of serine palmitoyltransferase-like DUF1295 PF06966.12 KEG12068.1 - 3.8e-10 39.7 0.8 5.4e-10 39.2 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KEG12068.1 - 3.2e-07 30.4 2.5 5.1e-07 29.8 2.5 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KEG12068.1 - 0.00023 21.5 0.0 0.00049 20.5 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KEG12068.1 - 0.00042 20.7 0.6 0.00089 19.6 0.4 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KEG12068.1 - 0.0041 16.0 0.8 0.0064 15.3 0.2 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4401 PF14351.6 KEG12068.1 - 0.02 14.2 1.8 0.046 13.0 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) PCRF PF03462.18 KEG12069.1 - 1e-26 94.0 0.1 1.8e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KEG12069.1 - 2.3e-25 88.8 0.4 6e-25 87.4 0.1 1.9 2 0 0 2 2 2 1 RF-1 domain CPT_N PF16484.5 KEG12069.1 - 0.063 13.3 0.2 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus DUF1126 PF06565.12 KEG12070.1 - 2.5e-67 223.3 1.3 1e-23 83.2 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 KEG12070.1 - 0.0061 17.0 0.2 0.22 12.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Cyclin_N PF00134.23 KEG12071.1 - 1.4e-36 125.0 0.0 2.4e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEG12071.1 - 9.5e-15 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.9 KEG12071.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus Fer2_2 PF01799.20 KEG12075.1 - 0.058 13.4 0.1 0.082 12.9 0.1 1.3 1 0 0 1 1 1 0 [2Fe-2S] binding domain IMS PF00817.20 KEG12076.1 - 1.2e-38 132.5 0.0 2.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KEG12076.1 - 0.00038 21.1 0.0 0.00083 20.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PGM_PMM_I PF02878.16 KEG12077.1 - 1.4e-31 109.0 0.1 2.4e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KEG12077.1 - 2.8e-25 88.7 0.0 7.5e-25 87.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEG12077.1 - 1.4e-09 38.5 0.0 3.7e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KEG12077.1 - 5.6e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ELYS PF13934.6 KEG12078.1 - 0.04 13.9 0.1 0.22 11.4 0.0 2.3 2 1 0 2 2 2 0 Nuclear pore complex assembly ParA PF10609.9 KEG12079.1 - 7.1e-87 290.9 0.1 8.3e-87 290.7 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEG12079.1 - 1.2e-12 48.0 0.0 7.7e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEG12079.1 - 1.3e-08 34.9 0.4 2.7e-07 30.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KEG12079.1 - 4.8e-06 26.1 0.0 8e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 KEG12079.1 - 0.00026 20.1 0.2 0.00039 19.5 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 KEG12079.1 - 0.00042 19.6 0.1 0.00072 18.8 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase NB-ARC PF00931.22 KEG12079.1 - 0.0012 18.1 0.2 0.0021 17.3 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 KEG12079.1 - 0.0031 17.4 0.1 0.0062 16.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_26 PF13500.6 KEG12079.1 - 0.0071 16.2 0.2 0.098 12.5 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG12079.1 - 0.011 16.1 0.1 0.017 15.5 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KEG12079.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KEG12079.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KEG12079.1 - 0.031 14.8 0.1 0.046 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEG12079.1 - 0.036 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEG12079.1 - 0.043 13.7 0.2 0.068 13.1 0.2 1.3 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KEG12079.1 - 0.054 13.4 0.1 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain TF_Zn_Ribbon PF08271.12 KEG12079.1 - 0.061 12.8 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Fer4_NifH PF00142.18 KEG12079.1 - 0.071 12.6 0.2 0.18 11.2 0.2 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 KEG12079.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Zn_Tnp_IS1595 PF12760.7 KEG12079.1 - 0.077 13.0 0.1 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SMC_N PF02463.19 KEG12079.1 - 0.084 12.3 0.4 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 KEG12079.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 NTPase DUF1610 PF07754.11 KEG12079.1 - 0.11 12.5 0.9 0.11 12.5 0.9 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF1610) AAA_29 PF13555.6 KEG12079.1 - 0.15 11.8 0.3 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KEG12079.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG12079.1 - 0.18 11.4 0.5 0.28 10.8 0.2 1.4 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KEG12079.1 - 0.2 11.3 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Hist_deacetyl PF00850.19 KEG12080.1 - 1.2e-73 248.3 0.0 1.5e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PB1 PF00564.24 KEG12081.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 PB1 domain EF-hand_7 PF13499.6 KEG12082.1 - 1e-08 35.5 0.0 5.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG12082.1 - 1.6e-08 33.8 0.1 0.00016 21.4 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEG12082.1 - 3.5e-07 29.3 0.3 5.3e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KEG12082.1 - 1.3e-06 28.1 0.0 0.0003 20.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KEG12082.1 - 0.00043 20.5 0.0 0.68 10.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF2070 PF09843.9 KEG12083.1 - 0.6 8.3 4.1 0.64 8.2 4.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC_tran PF00005.27 KEG12084.1 - 7.7e-37 126.9 0.0 1.7e-17 64.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEG12084.1 - 2e-11 43.8 1.4 0.019 14.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEG12084.1 - 3.2e-11 43.6 2.7 0.037 13.8 0.0 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 KEG12084.1 - 1.1e-09 37.9 3.2 2.7e-09 36.7 3.2 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 KEG12084.1 - 2.6e-09 36.5 2.0 2.6e-09 36.5 2.0 2.3 3 0 0 3 3 1 1 4Fe-4S binding domain Fer4_6 PF12837.7 KEG12084.1 - 1.6e-06 27.9 1.3 1.6e-06 27.9 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 KEG12084.1 - 3.4e-06 27.0 0.0 0.032 14.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 KEG12084.1 - 7.9e-06 26.4 0.4 0.0049 17.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEG12084.1 - 8.8e-06 26.0 0.7 0.0014 18.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEG12084.1 - 1.3e-05 25.8 0.7 0.01 16.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEG12084.1 - 5.3e-05 22.9 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEG12084.1 - 9.2e-05 22.4 0.2 0.072 13.0 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase Fer4_7 PF12838.7 KEG12084.1 - 0.00028 21.4 10.2 0.00035 21.1 0.6 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.6 KEG12084.1 - 0.00041 20.6 0.0 0.69 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KEG12084.1 - 0.00046 20.6 0.0 0.05 14.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEG12084.1 - 0.00056 19.9 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain Fer4_21 PF14697.6 KEG12084.1 - 0.00068 19.7 15.7 0.0016 18.6 15.7 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.12 KEG12084.1 - 0.0013 18.6 1.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_10 PF13237.6 KEG12084.1 - 0.0016 18.5 1.4 0.0016 18.5 1.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KEG12084.1 - 0.0026 17.8 1.0 0.0026 17.8 1.0 3.1 2 1 0 2 2 1 1 4Fe-4S binding domain AAA_13 PF13166.6 KEG12084.1 - 0.0033 16.1 0.1 0.043 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Fer4_3 PF12798.7 KEG12084.1 - 0.0039 18.0 4.9 0.0039 18.0 4.9 2.8 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_24 PF13479.6 KEG12084.1 - 0.0053 16.5 0.5 0.55 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEG12084.1 - 0.0058 16.4 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEG12084.1 - 0.0059 17.0 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_9 PF13187.6 KEG12084.1 - 0.0063 16.7 13.9 0.014 15.5 13.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 KEG12084.1 - 0.0064 16.7 0.0 2.5 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 KEG12084.1 - 0.0085 15.7 0.9 0.65 9.6 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_16 PF13484.6 KEG12084.1 - 0.0091 16.9 0.2 0.0091 16.9 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_14 PF13173.6 KEG12084.1 - 0.014 15.4 0.0 0.96 9.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KEG12084.1 - 0.014 15.4 0.3 4 7.5 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase TsaE PF02367.17 KEG12084.1 - 0.022 14.8 0.1 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VirE PF05272.11 KEG12084.1 - 0.022 14.5 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Roc PF08477.13 KEG12084.1 - 0.023 14.9 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Fer4_4 PF12800.7 KEG12084.1 - 0.023 15.2 2.4 0.023 15.2 2.4 2.5 2 0 0 2 2 1 0 4Fe-4S binding domain AAA_7 PF12775.7 KEG12084.1 - 0.026 14.1 0.0 1.5 8.3 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KEG12084.1 - 0.033 14.7 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEG12084.1 - 0.046 13.7 0.3 2.7 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEG12084.1 - 0.053 13.1 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KEG12084.1 - 0.054 12.3 0.1 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_27 PF13514.6 KEG12084.1 - 0.087 12.4 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KEG12084.1 - 0.091 11.9 0.0 0.88 8.7 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KEG12084.1 - 0.11 12.3 2.0 0.42 10.4 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KEG12084.1 - 0.11 11.7 0.1 7.7 5.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 KEG12084.1 - 0.13 11.5 2.6 6 6.1 0.0 3.1 2 1 1 3 3 3 0 Zeta toxin Fer4_17 PF13534.6 KEG12084.1 - 8.2 7.1 15.3 95 3.7 15.5 2.4 1 1 1 2 2 1 0 4Fe-4S dicluster domain DSPc PF00782.20 KEG12085.1 - 9.2e-21 74.1 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Leu_Phe_trans PF03588.14 KEG12087.1 - 2.2e-05 24.0 0.1 0.00025 20.6 0.0 2.3 3 0 0 3 3 3 1 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.18 KEG12088.1 - 3.7e-29 100.8 5.7 4.5e-29 100.5 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Pkinase PF00069.25 KEG12090.1 - 2.8e-57 194.1 0.0 3.9e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12090.1 - 3.6e-26 92.0 0.0 1.5e-25 90.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG12090.1 - 0.00015 21.8 0.3 0.081 12.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KEG12090.1 - 0.035 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KEG12090.1 - 0.046 13.3 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KEG12090.1 - 0.25 10.2 0.0 0.41 9.5 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain KASH_CCD PF14662.6 KEG12091.1 - 0.0048 16.8 18.2 0.11 12.4 8.5 3.3 3 1 0 3 3 3 2 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KEG12091.1 - 0.0053 16.8 6.7 2 8.6 0.4 4.2 3 0 0 3 3 3 2 bZIP transcription factor TSC22 PF01166.18 KEG12091.1 - 0.039 14.3 4.2 3.3 8.1 0.3 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family HAP1_N PF04849.13 KEG12091.1 - 0.039 13.1 15.5 0.33 10.1 0.4 3.1 2 1 0 2 2 2 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 KEG12091.1 - 0.083 13.3 3.3 15 6.1 0.3 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Elf4 PF07011.11 KEG12091.1 - 0.1 12.6 0.2 4 7.4 0.0 2.8 3 0 0 3 3 3 0 Early Flowering 4 domain DASH_Dad4 PF08650.10 KEG12091.1 - 0.18 11.8 1.5 14 5.8 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad4 TMF_DNA_bd PF12329.8 KEG12091.1 - 0.39 10.7 10.8 0.49 10.4 0.1 4.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding WD40_alt PF14077.6 KEG12091.1 - 0.53 10.2 0.1 0.53 10.2 0.1 3.3 4 0 0 4 4 4 0 Alternative WD40 repeat motif bZIP_2 PF07716.15 KEG12091.1 - 0.61 10.2 14.3 0.54 10.4 0.8 4.3 4 0 0 4 4 4 0 Basic region leucine zipper GrpE PF01025.19 KEG12091.1 - 1.7 8.3 15.1 0.13 11.9 5.6 2.9 3 0 0 3 3 3 0 GrpE Complex1_LYR_2 PF13233.6 KEG12091.1 - 2.6 8.8 9.2 0.32 11.8 1.6 2.9 3 0 0 3 3 2 0 Complex1_LYR-like DivIC PF04977.15 KEG12091.1 - 3.4 7.5 15.6 9.6 6.1 0.4 4.9 4 1 2 6 6 6 0 Septum formation initiator Leu_zip PF15294.6 KEG12091.1 - 7.2 6.0 16.6 1.9 7.9 6.1 3.2 2 1 1 3 3 3 0 Leucine zipper DASH_Dad2 PF08654.10 KEG12091.1 - 7.5 7.0 8.8 1.5 9.2 0.1 3.9 4 2 0 4 4 4 0 DASH complex subunit Dad2 Rho_Binding PF08912.11 KEG12091.1 - 8.7 7.2 12.6 15 6.5 1.7 4.2 3 0 0 3 3 3 0 Rho Binding DUF4482 PF14818.6 KEG12091.1 - 8.8 7.2 19.4 0.63 10.9 0.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4482) Spc7 PF08317.11 KEG12091.1 - 9.9 4.9 21.0 4.2 6.2 1.0 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2462 PF09495.10 KEG12092.1 - 0.0013 19.5 5.8 0.0013 19.5 5.8 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Dynein_C PF18199.1 KEG12093.1 - 7.3e-33 114.1 0.0 8e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_6 PF12774.7 KEG12094.1 - 5e-151 502.3 0.0 1.4e-148 494.2 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG12094.1 - 1.1e-122 410.0 4.8 1.1e-122 410.0 4.8 4.5 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG12094.1 - 5.7e-91 304.4 0.1 2.1e-89 299.3 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KEG12094.1 - 1.3e-81 273.0 4.8 2.3e-81 272.1 0.8 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KEG12094.1 - 1.7e-65 219.9 0.2 4e-60 202.4 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_C PF18199.1 KEG12094.1 - 2.9e-59 200.8 0.2 2.9e-59 200.8 0.2 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 KEG12094.1 - 1.3e-52 178.0 0.0 3.4e-52 176.6 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KEG12094.1 - 1.6e-51 175.4 0.7 4.6e-51 173.9 0.7 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KEG12094.1 - 2.9e-45 153.2 0.0 2.4e-44 150.2 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KEG12094.1 - 5.1e-29 101.0 0.0 2.6e-28 98.7 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KEG12094.1 - 6.4e-12 45.7 3.1 0.00055 20.0 0.0 7.0 7 1 0 7 7 6 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KEG12094.1 - 1.8e-11 44.1 0.0 8.1e-11 42.0 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain T2SSE PF00437.20 KEG12094.1 - 3.3e-06 26.4 0.1 0.0031 16.6 0.0 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KEG12094.1 - 4.4e-06 27.1 0.2 0.055 13.9 0.0 3.8 3 0 0 3 3 3 2 RNA helicase AAA PF00004.29 KEG12094.1 - 5.1e-06 27.0 0.7 1.9 8.9 0.0 4.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KEG12094.1 - 7.1e-06 25.9 4.0 0.59 9.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KEG12094.1 - 4.4e-05 23.8 13.0 0.38 11.0 0.0 7.1 8 0 0 8 8 6 1 AAA domain Mg_chelatase PF01078.21 KEG12094.1 - 0.00016 21.1 1.1 0.067 12.6 0.1 4.6 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KEG12094.1 - 0.00039 20.8 4.7 4.8 7.5 0.0 5.6 5 1 0 5 5 4 1 AAA ATPase domain AAA_24 PF13479.6 KEG12094.1 - 0.00047 19.9 0.3 0.46 10.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KEG12094.1 - 0.0014 18.4 1.5 14 5.3 0.0 4.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_18 PF13238.6 KEG12094.1 - 0.012 16.2 11.6 0.12 12.9 0.0 5.3 6 0 0 6 6 5 0 AAA domain DEAD PF00270.29 KEG12094.1 - 0.014 15.2 0.4 1.7 8.4 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 KEG12094.1 - 0.02 15.1 0.3 33 4.7 0.0 4.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KEG12094.1 - 0.036 13.5 6.3 0.6 9.5 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein AAA_25 PF13481.6 KEG12094.1 - 0.046 13.3 5.4 0.98 9.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain DUF853 PF05872.12 KEG12094.1 - 0.12 11.0 2.7 21 3.5 0.1 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) NACHT PF05729.12 KEG12094.1 - 0.14 12.0 1.2 14 5.5 0.1 3.6 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 KEG12094.1 - 0.65 10.3 2.3 61 3.9 0.1 3.8 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 KEG12094.1 - 0.9 9.1 3.8 28 4.2 0.1 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Vac_Fusion PF02346.16 KEG12094.1 - 2.2 8.0 5.4 3.5 7.3 0.3 4.0 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 AAA_33 PF13671.6 KEG12094.1 - 6.4 6.9 13.9 6.2 7.0 0.0 5.4 6 0 0 6 6 5 0 AAA domain Pkinase PF00069.25 KEG12095.1 - 6.8e-51 173.2 0.0 2.8e-50 171.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12095.1 - 2.8e-37 128.4 0.0 5.3e-35 120.9 0.0 3.1 3 0 0 3 3 3 1 Protein tyrosine kinase TetR_C_27 PF17935.1 KEG12095.1 - 0.0039 17.2 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF1902 PF08972.11 KEG12095.1 - 0.007 16.3 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) RIO1 PF01163.22 KEG12095.1 - 0.038 13.6 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family TetR_C_16 PF17920.1 KEG12095.1 - 0.36 11.1 3.3 17 5.7 0.3 3.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain ER_lumen_recept PF00810.18 KEG12096.1 - 4.1e-52 176.9 8.1 6.9e-52 176.2 8.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Peptidase_M20 PF01546.28 KEG12097.1 - 7.7e-21 74.7 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEG12097.1 - 2.5e-06 27.4 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain adh_short PF00106.25 KEG12099.1 - 2.3e-33 115.3 0.0 3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEG12099.1 - 4.8e-23 81.9 0.0 6.6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG12099.1 - 0.00094 19.1 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEG12099.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ANAPC4_WD40 PF12894.7 KEG12100.1 - 6.9e-06 26.3 0.0 0.11 12.8 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG12100.1 - 0.023 15.6 0.5 12 7.0 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribul_P_3_epim PF00834.19 KEG12102.1 - 1.3e-64 217.2 0.1 1.5e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Radical_SAM PF04055.21 KEG12102.1 - 0.008 16.6 0.0 0.023 15.1 0.0 1.8 1 1 1 2 2 2 1 Radical SAM superfamily OMPdecase PF00215.24 KEG12102.1 - 0.035 13.7 0.2 0.087 12.4 0.1 1.8 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 KEG12102.1 - 0.04 13.4 0.1 0.099 12.1 0.0 1.7 1 1 1 2 2 2 0 Histidine biosynthesis protein QRPTase_C PF01729.19 KEG12102.1 - 0.042 13.6 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PRA1 PF03208.19 KEG12104.1 - 3.3e-31 107.8 9.2 3.8e-31 107.7 9.2 1.0 1 0 0 1 1 1 1 PRA1 family protein PDZ_6 PF17820.1 KEG12105.1 - 0.0027 17.5 0.7 7.6 6.5 0.0 4.0 4 0 0 4 4 4 2 PDZ domain AIF-MLS PF14962.6 KEG12105.1 - 1 9.3 13.7 2.3 8.2 13.7 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence PRA1 PF03208.19 KEG12106.1 - 8.5e-14 51.4 1.4 1.6e-13 50.5 1.4 1.4 1 0 0 1 1 1 1 PRA1 family protein DUF3561 PF12084.8 KEG12106.1 - 0.14 12.2 5.1 11 6.1 4.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3561) Ytca PF17090.5 KEG12106.1 - 0.84 10.2 6.7 0.2 12.2 2.5 2.1 2 1 0 2 2 2 0 Uncharacterised protein family TPR_16 PF13432.6 KEG12108.1 - 0.12 13.0 9.4 1.6 9.5 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3789 PF12664.7 KEG12109.1 - 0.27 11.0 2.5 0.83 9.4 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) ubiquitin PF00240.23 KEG12110.1 - 1.6e-10 40.6 0.0 4.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family SAP130_C PF16014.5 KEG12110.1 - 8.4 5.4 8.4 11 4.9 8.4 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Penicillinase_R PF03965.16 KEG12112.1 - 0.039 14.3 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Penicillinase repressor Sin_N PF04801.13 KEG12112.1 - 0.052 12.8 13.1 0.0096 15.2 5.6 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region Pep1_7 PF17232.2 KEG12112.1 - 5 7.7 9.7 2.5 8.6 1.9 3.8 3 1 0 3 3 3 0 Elicitor peptide 1-7 Presenilin PF01080.17 KEG12112.1 - 7.2 5.3 14.7 4 6.1 0.4 2.3 2 0 0 2 2 2 0 Presenilin Sulfotransfer_4 PF17784.1 KEG12113.1 - 1.1e-44 152.9 0.0 1.7e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain NIF PF03031.18 KEG12117.1 - 4.6e-26 91.5 0.0 3.3e-21 75.7 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD PF12710.7 KEG12117.1 - 0.014 15.8 0.0 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Macoilin PF09726.9 KEG12117.1 - 1.5 7.3 7.6 2.5 6.5 7.6 1.2 1 0 0 1 1 1 0 Macoilin family Cyclin PF08613.11 KEG12118.1 - 8.2e-36 123.8 0.0 2.7e-35 122.1 0.0 2.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEG12118.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain CDC37_N PF03234.14 KEG12119.1 - 0.78 10.7 8.2 7.9 7.4 3.5 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF2514 PF10721.9 KEG12119.1 - 5.7 6.9 8.4 3.4 7.7 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) zf-MIZ PF02891.20 KEG12120.1 - 2.8e-19 68.6 9.8 5.9e-19 67.6 9.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger MRNIP PF15749.5 KEG12120.1 - 0.034 14.9 0.6 0.08 13.7 0.6 1.6 1 0 0 1 1 1 0 MRN-interacting protein zf-Nse PF11789.8 KEG12120.1 - 1.3 8.9 6.9 4 7.3 6.5 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.25 KEG12121.1 - 1.8e-69 234.1 0.0 2.1e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12121.1 - 9.1e-34 116.9 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG12121.1 - 3.3e-06 26.6 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEG12121.1 - 0.047 12.6 0.2 0.066 12.2 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KEG12121.1 - 0.049 12.4 0.0 0.76 8.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KEG12121.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PROCN PF08083.11 KEG12122.1 - 6.4e-190 631.1 8.9 1.4e-189 630.0 8.9 1.6 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KEG12122.1 - 4.9e-88 294.6 0.0 8e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KEG12122.1 - 1.2e-66 223.5 0.0 2.8e-66 222.4 0.0 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KEG12122.1 - 6.5e-61 204.7 0.0 1.3e-60 203.7 0.0 1.5 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KEG12122.1 - 9.7e-57 190.8 0.0 3e-56 189.2 0.0 1.9 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KEG12122.1 - 4.5e-36 123.1 0.0 1.1e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KEG12122.1 - 1.3e-27 96.1 0.0 2.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain YqgB PF11036.8 KEG12123.1 - 0.56 10.0 2.8 0.41 10.4 0.6 1.9 2 0 0 2 2 2 0 Virulence promoting factor MRP-S22 PF10245.9 KEG12124.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 INCENP_N PF12178.8 KEG12124.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal UNC-50 PF05216.13 KEG12125.1 - 1.1e-65 221.3 15.7 1.3e-65 221.1 15.7 1.0 1 0 0 1 1 1 1 UNC-50 family Oxidored_q2 PF00420.24 KEG12125.1 - 0.16 11.6 11.2 0.086 12.5 3.7 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SHIPPO-rpt PF07004.12 KEG12126.1 - 2.1e-13 50.5 41.7 0.072 14.0 0.1 10.4 11 0 0 11 11 11 8 Sperm-tail PG-rich repeat TFIID-18kDa PF02269.16 KEG12128.1 - 0.047 13.7 0.2 0.1 12.7 0.2 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Mito_carr PF00153.27 KEG12129.1 - 3.6e-19 68.5 2.9 6.1e-12 45.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Seryl_tRNA_N PF02403.22 KEG12131.1 - 0.14 12.4 9.5 0.23 11.7 9.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Draxin PF15550.6 KEG12131.1 - 0.53 10.1 12.6 0.62 9.9 12.6 1.0 1 0 0 1 1 1 0 Draxin TT_ORF2 PF02957.15 KEG12131.1 - 6.2 7.8 9.9 5.1 8.0 6.6 2.0 1 1 1 2 2 2 0 TT viral ORF2 FUSC PF04632.12 KEG12131.1 - 9.3 4.6 9.7 11 4.4 9.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1616 PF07760.11 KEG12132.1 - 0.0032 16.9 0.1 0.0091 15.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1616) stn_TNFRSF12A PF12191.8 KEG12132.1 - 0.011 16.0 0.9 0.066 13.4 0.3 2.4 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Spermine_synth PF01564.17 KEG12133.1 - 5.4e-54 182.5 0.0 8.7e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KEG12133.1 - 4e-16 58.6 0.0 8.3e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KEG12133.1 - 8.2e-05 23.2 0.0 0.00014 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DRE2_N PF16803.5 KEG12133.1 - 0.0046 17.2 0.0 0.0075 16.5 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Methyltransf_11 PF08241.12 KEG12133.1 - 0.0059 17.2 0.0 0.022 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG12133.1 - 0.017 15.8 0.0 0.064 14.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEG12133.1 - 0.09 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KEG12133.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DENN PF02141.21 KEG12134.1 - 1e-10 41.9 0.3 1.9e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Avl9 PF09794.9 KEG12134.1 - 0.15 10.8 0.0 1.8 7.2 0.1 2.2 1 1 1 2 2 2 0 Transport protein Avl9 Y_phosphatase2 PF03162.13 KEG12136.1 - 5.8e-53 178.9 0.0 7.8e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KEG12136.1 - 2.1e-09 37.7 0.0 5.6e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEG12136.1 - 0.00054 19.6 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KEG12136.1 - 0.0056 16.5 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KEG12136.1 - 0.033 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 KEG12136.1 - 0.099 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain SSP160 PF06933.11 KEG12136.1 - 0.87 7.7 13.4 1.1 7.3 13.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 KEG12136.1 - 1.6 6.7 5.8 2 6.5 5.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAM199X PF15814.5 KEG12136.1 - 6 5.8 9.8 8.4 5.3 9.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X TPR_19 PF14559.6 KEG12138.1 - 8.8e-38 128.7 55.2 4.3e-06 27.1 0.0 15.7 11 5 5 16 16 16 9 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12138.1 - 2.6e-30 102.1 58.4 0.0003 20.7 0.2 19.5 21 0 0 21 21 18 8 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12138.1 - 2.7e-27 93.1 60.1 0.017 15.9 0.2 20.8 12 6 9 22 22 22 7 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12138.1 - 4.5e-26 88.8 28.9 8.3e-05 22.5 0.2 15.1 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEG12138.1 - 5.3e-24 84.6 65.8 0.00031 21.3 0.1 15.0 14 4 2 17 17 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 KEG12138.1 - 6.9e-21 73.1 44.8 9.4e-06 25.2 0.4 15.5 18 0 0 18 18 16 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG12138.1 - 2.6e-13 50.0 34.0 0.19 11.9 0.3 10.8 8 2 2 11 11 11 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEG12138.1 - 1.3e-11 44.1 23.8 0.27 11.7 0.0 12.5 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEG12138.1 - 2.3e-11 43.8 59.2 0.0012 19.1 0.7 13.4 11 3 2 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 KEG12138.1 - 1.4e-10 40.4 33.8 0.0083 16.1 0.0 11.4 12 0 0 12 12 11 4 Tetratricopeptide repeat NARP1 PF12569.8 KEG12138.1 - 3.2e-08 33.0 12.7 2e-05 23.8 0.1 5.5 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 RPN7 PF10602.9 KEG12138.1 - 7.8e-07 29.0 14.9 0.0029 17.3 0.2 6.9 7 1 0 7 7 7 1 26S proteasome subunit RPN7 HrpB1_HrpK PF09613.10 KEG12138.1 - 8.8e-06 25.4 18.8 0.022 14.4 0.2 6.6 5 1 1 6 6 6 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 KEG12138.1 - 1.1e-05 25.7 46.5 0.42 11.4 0.1 16.8 18 0 0 18 18 18 1 Tetratricopeptide repeat FAT PF02259.23 KEG12138.1 - 8e-05 22.0 13.6 0.21 10.8 1.6 5.6 5 1 1 6 6 6 3 FAT domain TPR_11 PF13414.6 KEG12138.1 - 0.0054 16.4 35.0 0.51 10.1 0.9 10.4 11 2 0 11 11 10 2 TPR repeat SNAP PF14938.6 KEG12138.1 - 0.023 14.1 26.8 1.2 8.5 0.8 6.8 6 2 1 7 7 7 0 Soluble NSF attachment protein, SNAP HemY_N PF07219.13 KEG12138.1 - 0.15 12.2 11.8 28 5.0 0.2 6.1 6 0 0 6 6 5 0 HemY protein N-terminus ANAPC5 PF12862.7 KEG12138.1 - 0.45 10.6 18.5 32 4.7 6.5 6.4 6 1 0 6 6 4 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KEG12138.1 - 0.74 9.8 39.0 0.93 9.5 0.3 10.5 11 0 0 11 11 11 0 Tetratricopeptide repeat MIT PF04212.18 KEG12138.1 - 1.4 9.0 19.2 7.4 6.7 0.1 7.1 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain GPI2 PF06432.11 KEG12140.1 - 9.7e-73 245.0 10.9 1.1e-72 244.8 10.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Beach PF02138.18 KEG12141.1 - 3.2e-106 354.8 0.0 5.2e-106 354.0 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KEG12141.1 - 1.2e-12 48.2 0.0 2.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KEG12141.1 - 6.9e-10 38.9 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KEG12141.1 - 2.3e-06 28.2 0.0 0.033 15.1 0.0 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat XPG_I PF00867.18 KEG12141.1 - 0.016 15.5 0.1 0.053 13.9 0.1 1.8 1 0 0 1 1 1 0 XPG I-region Sec34 PF04136.15 KEG12142.1 - 1.2e-16 60.9 2.7 1.2e-16 60.9 0.4 2.1 2 0 0 2 2 2 1 Sec34-like family Hpt PF01627.23 KEG12142.1 - 0.22 11.8 6.5 8.4 6.7 0.9 3.5 2 1 0 2 2 2 0 Hpt domain UPF0242 PF06785.11 KEG12142.1 - 0.41 10.7 6.3 0.34 11.0 0.1 3.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF2203 PF09969.9 KEG12142.1 - 5.6 7.7 8.2 2.1 9.1 0.1 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) Lactonase PF10282.9 KEG12144.1 - 0.0086 15.4 0.6 0.12 11.6 0.0 2.5 2 2 0 2 2 2 1 Lactonase, 7-bladed beta-propeller FAD_binding_8 PF08022.12 KEG12144.1 - 0.12 12.5 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-binding domain DUF1180 PF06679.12 KEG12144.1 - 2 8.8 3.6 1 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Amastin PF07344.11 KEG12145.1 - 1.5e-32 112.6 3.9 2e-32 112.2 3.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 KEG12145.1 - 0.0025 17.7 3.3 0.0037 17.2 3.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Hol_Tox PF16935.5 KEG12145.1 - 0.14 12.2 8.7 0.38 10.8 0.1 3.4 3 0 0 3 3 3 0 Putative Holin-like Toxin (Hol-Tox) DUF4094 PF13334.6 KEG12145.1 - 0.92 10.0 3.6 5.5 7.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) GlcNAc PF11397.8 KEG12146.1 - 1.1e-126 423.0 0.0 1.4e-126 422.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Amidase PF01425.21 KEG12147.1 - 4.8e-06 25.8 0.0 0.0048 15.9 0.0 2.3 2 0 0 2 2 2 2 Amidase PI3_PI4_kinase PF00454.27 KEG12148.1 - 0.18 11.6 0.0 0.77 9.5 0.0 2.0 3 0 0 3 3 3 0 Phosphatidylinositol 3- and 4-kinase Spt20 PF12090.8 KEG12149.1 - 0.0004 20.1 12.0 0.0004 20.1 12.0 1.7 2 0 0 2 2 2 1 Spt20 family TFIIA PF03153.13 KEG12149.1 - 0.0036 17.4 14.0 0.0036 17.4 14.0 3.7 3 1 0 3 3 2 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KEG12149.1 - 0.028 13.4 18.3 0.056 12.4 13.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RLL PF10036.9 KEG12149.1 - 0.028 14.3 2.2 0.12 12.2 1.3 2.4 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF3437 PF11919.8 KEG12149.1 - 0.061 13.2 0.5 0.63 10.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 KEG12149.1 - 0.077 13.4 2.7 0.34 11.3 0.4 3.5 3 0 0 3 3 2 0 HEAT repeats eIF3_p135 PF12807.7 KEG12149.1 - 0.16 12.0 3.1 7.6 6.5 0.4 2.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 FAM176 PF14851.6 KEG12149.1 - 0.44 10.2 5.9 4 7.1 0.1 2.5 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 KEG12149.1 - 1.8 9.6 8.9 6.3 7.8 5.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 KEG12149.1 - 1.8 8.7 5.1 5.4 7.2 1.2 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 KEG12149.1 - 4.1 7.3 6.6 11 5.9 6.6 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NOA36 PF06524.12 KEG12149.1 - 6.9 5.9 7.6 15 4.8 7.6 1.5 1 0 0 1 1 1 0 NOA36 protein Cyt_bd_oxida_II PF02322.15 KEG12150.1 - 0.084 12.2 0.4 0.095 12.1 0.4 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II PerC PF06069.11 KEG12151.1 - 0.0079 16.4 0.8 0.54 10.5 0.2 2.3 2 0 0 2 2 2 2 PerC transcriptional activator Mak10 PF04112.13 KEG12152.1 - 0.00031 20.3 0.0 0.014 15.0 0.0 2.3 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Aha1_N PF09229.11 KEG12153.1 - 1.6e-25 89.9 0.0 2.2e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KEG12153.1 - 1.7e-14 54.1 0.0 2.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein CAP_N PF01213.19 KEG12153.1 - 0.14 11.6 1.1 0.2 11.1 1.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.6 KEG12153.1 - 0.16 10.9 0.6 0.24 10.4 0.6 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Amino_oxidase PF01593.24 KEG12154.1 - 1.1e-11 44.7 0.0 1.5e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEG12154.1 - 1.2e-07 31.8 0.3 4e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEG12154.1 - 0.00011 21.9 0.0 0.00047 19.8 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEG12154.1 - 0.0016 17.8 0.0 0.018 14.3 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG12154.1 - 0.014 14.7 0.0 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEG12154.1 - 0.034 14.1 0.1 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KEG12154.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEG12154.1 - 0.22 10.7 0.4 0.36 10.0 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Lipase_3 PF01764.25 KEG12155.1 - 3.9e-13 49.5 0.0 6.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KEG12155.1 - 0.00075 20.2 0.0 0.002 18.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Metallophos PF00149.28 KEG12156.1 - 4.9e-32 112.1 0.4 2.5e-31 109.8 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KEG12156.1 - 2e-20 72.9 0.0 4.5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 KEG12156.1 - 7.4e-16 57.2 1.6 1.2e-05 24.9 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12156.1 - 2.3e-14 52.3 3.2 7.1e-05 22.6 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12156.1 - 9.7e-08 31.6 0.1 0.0019 17.8 0.2 3.6 2 1 1 3 3 3 2 TPR repeat BTAD PF03704.17 KEG12156.1 - 1.1e-07 32.4 1.1 2e-07 31.6 1.1 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 KEG12156.1 - 2.8e-07 31.1 1.3 0.00083 20.0 1.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12156.1 - 3.7e-07 29.8 0.5 0.0013 18.8 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12156.1 - 8.2e-05 23.1 0.5 0.5 11.3 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG12156.1 - 0.0012 19.0 1.0 1.4 9.2 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG12156.1 - 0.0013 19.2 0.4 0.78 10.5 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEG12156.1 - 0.0028 16.9 0.1 0.82 8.8 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG12156.1 - 0.0083 16.1 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG12156.1 - 0.02 15.0 0.0 0.08 13.1 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG12156.1 - 0.06 13.6 1.3 7.1 6.9 0.2 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KEG12156.1 - 0.1 13.1 0.3 22 5.7 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG12156.1 - 0.16 12.4 0.3 1.7 9.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF21 PF01595.20 KEG12157.1 - 2e-26 92.8 0.1 4e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEG12157.1 - 5.4e-05 23.6 0.1 2.5 8.6 0.0 3.7 3 0 0 3 3 3 2 CBS domain DUF21 PF01595.20 KEG12158.1 - 2.1e-35 122.0 0.3 3.7e-35 121.2 0.3 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEG12158.1 - 0.0047 17.3 3.0 6.2 7.4 0.1 3.9 4 0 0 4 4 4 1 CBS domain cNMP_binding PF00027.29 KEG12158.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2070 PF09843.9 KEG12158.1 - 0.66 8.2 7.7 0.99 7.6 7.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TF_Zn_Ribbon PF08271.12 KEG12159.1 - 0.06 12.9 0.5 0.12 11.9 0.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF726 PF05277.12 KEG12160.1 - 6.8e-55 186.4 22.2 1.8e-51 175.1 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF726) PNK3P PF08645.11 KEG12161.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase CitT PF12431.8 KEG12161.1 - 0.22 11.9 0.5 0.71 10.3 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator Glyco_hydro_31 PF01055.26 KEG12162.1 - 8.1e-138 460.3 4.6 1e-137 460.0 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KEG12162.1 - 2.1e-15 56.8 0.4 6.9e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KEG12162.1 - 2.1e-06 27.9 0.0 4.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) 3Beta_HSD PF01073.19 KEG12163.1 - 3.7e-08 32.7 0.0 5.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEG12163.1 - 4.3e-06 26.7 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KEG12163.1 - 3.4e-05 24.3 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEG12163.1 - 6e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEG12163.1 - 0.0029 16.7 0.0 2.4 7.2 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain KR PF08659.10 KEG12163.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 KEG12163.1 - 0.028 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KEG12163.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family zf_CCCH_4 PF18345.1 KEG12164.1 - 2.9e-05 24.0 10.4 0.015 15.3 1.4 2.7 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KEG12164.1 - 0.0045 17.7 1.1 0.092 13.4 0.1 2.3 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 KEG12164.1 - 0.026 14.4 8.5 0.22 11.5 1.7 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG12164.1 - 0.04 13.7 7.3 0.99 9.3 0.3 2.9 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KEG12164.1 - 4.4 7.9 5.5 24 5.6 0.9 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KEG12165.1 - 7.7e-06 26.6 0.1 0.027 15.1 0.0 2.7 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KEG12165.1 - 0.0014 18.6 13.0 0.083 13.0 3.9 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KEG12165.1 - 0.0061 16.4 9.0 0.16 12.0 0.7 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_binding_1 PF00175.21 KEG12167.1 - 9.4e-27 93.8 0.0 1.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG12167.1 - 2.7e-19 69.4 0.0 4.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEG12167.1 - 0.089 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KEG12168.1 - 2.1e-24 86.3 0.0 3e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG12168.1 - 2e-20 73.0 0.0 3.6e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEG12168.1 - 0.00063 19.9 0.0 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.22 KEG12169.1 - 9.7e-15 54.9 0.2 3.5e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KEG12169.1 - 0.0092 16.6 0.0 0.03 15.0 0.0 1.9 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KEG12169.1 - 0.085 12.8 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 PUA domain OKR_DC_1_C PF03711.15 KEG12169.1 - 0.15 12.3 0.1 1.5 9.1 0.0 2.5 2 1 1 3 3 3 0 Orn/Lys/Arg decarboxylase, C-terminal domain LRR_6 PF13516.6 KEG12170.1 - 0.00024 20.9 3.1 0.49 10.6 0.0 3.6 4 0 0 4 4 4 3 Leucine Rich repeat zf-Sec23_Sec24 PF04810.15 KEG12171.1 - 0.00064 19.7 9.5 1.4 9.1 1.6 3.6 3 0 0 3 3 3 3 Sec23/Sec24 zinc finger zinc_ribbon_12 PF11331.8 KEG12171.1 - 0.0081 15.9 22.2 0.73 9.7 0.6 4.7 2 1 3 5 5 5 3 Probable zinc-ribbon domain Cytochrom_c3_2 PF14537.6 KEG12171.1 - 0.014 15.9 3.5 0.014 15.9 3.5 2.9 1 1 2 3 3 3 0 Cytochrome c3 MCR PF18509.1 KEG12171.1 - 0.015 14.9 4.8 1.8 8.2 0.6 3.1 2 0 0 2 2 2 0 Magnetochrome domain Mu-like_Com PF10122.9 KEG12171.1 - 0.027 13.9 0.1 0.027 13.9 0.1 3.2 3 1 1 4 4 4 0 Mu-like prophage protein Com zinc_ribbon_10 PF10058.9 KEG12171.1 - 0.067 12.9 0.2 0.067 12.9 0.2 3.5 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-CHY PF05495.12 KEG12171.1 - 0.086 13.3 13.0 2.1 8.9 8.7 3.2 1 1 1 2 2 2 0 CHY zinc finger PSCyt2 PF07583.11 KEG12171.1 - 0.69 9.8 2.1 0.73 9.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) Cytochrom_C PF00034.21 KEG12171.1 - 3.1 9.0 8.6 0.69 11.1 0.3 3.0 3 1 1 4 4 3 0 Cytochrome c Cytochrome_C7 PF14522.6 KEG12171.1 - 4.3 7.4 18.4 0.62 10.1 7.7 3.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c TackOD1 PF18551.1 KEG12171.1 - 8 6.1 13.2 2.8 7.6 5.1 2.4 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 Elf1 PF05129.13 KEG12171.1 - 9.5 6.3 16.2 4.5 7.4 1.3 3.6 1 1 1 3 3 3 0 Transcription elongation factor Elf1 like Pkinase PF00069.25 KEG12172.1 - 8.7e-64 215.4 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12172.1 - 1.5e-34 119.4 0.0 2.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG12172.1 - 0.0008 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG12172.1 - 0.002 17.0 0.4 0.0044 15.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KEG12172.1 - 0.012 15.5 0.4 0.68 9.8 0.0 2.8 1 1 2 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG12172.1 - 0.051 12.5 0.1 0.1 11.6 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Ribosomal_L22 PF00237.19 KEG12173.1 - 7.2e-14 51.9 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PRIMA1 PF16101.5 KEG12175.1 - 0.068 13.2 5.8 0.088 12.8 5.8 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KEG12175.1 - 0.22 11.0 4.0 0.23 10.9 4.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RIBIOP_C PF04950.12 KEG12177.1 - 1.5e-91 306.9 0.0 2e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KEG12177.1 - 4.8e-16 58.6 0.0 1.2e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 AARP2CN (NUC121) domain zf-H3C2 PF16721.5 KEG12177.1 - 0.056 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding Acyl-CoA_dh_M PF02770.19 KEG12178.1 - 6.2e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEG12178.1 - 1.2e-07 32.3 0.0 3.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain MaoC_dehydratas PF01575.19 KEG12180.1 - 1.8e-18 66.3 0.0 2.4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KEG12180.1 - 5.4e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 KEG12180.1 - 0.0074 16.6 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 Thioesterase superfamily SIN1_PH PF16979.5 KEG12181.1 - 0.00039 20.7 0.0 0.00083 19.6 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology LicD PF04991.13 KEG12182.1 - 0.0063 16.7 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 LicD family EamA PF00892.20 KEG12183.1 - 3.2e-15 56.5 30.3 7.6e-08 32.6 4.1 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 KEG12183.1 - 1.1e-08 34.9 10.8 5.4e-08 32.7 10.8 1.9 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KEG12183.1 - 1e-07 31.5 3.3 1e-07 31.5 3.3 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KEG12183.1 - 0.00056 19.4 5.7 0.00098 18.6 5.7 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 KEG12183.1 - 0.015 14.3 6.4 0.49 9.3 0.4 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like CSG2 PF16965.5 KEG12183.1 - 0.034 13.1 4.0 0.019 13.9 1.4 1.8 2 0 0 2 2 2 0 Ceramide synthase regulator UAA PF08449.11 KEG12183.1 - 0.094 11.9 11.6 0.65 9.1 11.6 2.0 1 1 0 1 1 1 0 UAA transporter family Rav1p_C PF12234.8 KEG12185.1 - 1.5e-44 152.5 0.8 2.5e-44 151.8 0.8 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KEG12185.1 - 1.6e-05 25.5 0.3 0.0039 18.0 0.1 3.5 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF1674 PF07896.12 KEG12186.1 - 4e-12 46.4 0.0 6.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Menin PF05053.13 KEG12187.1 - 0.18 10.1 18.9 0.02 13.3 14.4 1.5 1 1 1 2 2 2 0 Menin Spt20 PF12090.8 KEG12188.1 - 0.11 12.1 12.0 0.39 10.3 12.0 1.9 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 KEG12188.1 - 0.93 10.5 10.6 7.9 7.5 0.2 5.4 5 1 0 5 5 5 0 WD domain, G-beta repeat Med15 PF09606.10 KEG12188.1 - 1.2 7.8 13.7 0.57 8.8 11.2 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCD PF05292.11 KEG12189.1 - 1.1e-69 234.9 0.3 8.7e-46 156.6 0.0 3.0 2 1 1 3 3 3 2 Malonyl-CoA decarboxylase C-terminal domain SUIM_assoc PF16619.5 KEG12189.1 - 0.07 13.2 3.3 0.23 11.5 3.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-C3H2C3 PF17122.5 KEG12190.1 - 0.0034 17.4 0.5 0.0091 16.0 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger Zn_ribbon_17 PF17120.5 KEG12190.1 - 0.21 11.2 2.9 0.46 10.1 0.2 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KEG12190.1 - 0.48 10.8 3.7 0.82 10.0 0.8 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEG12190.1 - 0.78 10.1 5.9 0.21 12.0 0.5 3.0 3 0 0 3 3 3 0 Ring finger domain TPR_4 PF07721.14 KEG12190.1 - 3.6 8.5 8.9 19 6.3 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Flu_NP PF00506.18 KEG12191.1 - 0.0064 15.2 0.1 0.01 14.5 0.1 1.2 1 0 0 1 1 1 1 Influenza virus nucleoprotein EF-hand_1 PF00036.32 KEG12192.1 - 3.2e-26 88.9 12.0 2.3e-09 36.1 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KEG12192.1 - 4.1e-22 76.2 6.9 5.3e-09 35.3 0.1 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 KEG12192.1 - 1.2e-21 76.9 10.8 7e-13 48.8 2.8 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEG12192.1 - 8.2e-19 67.2 8.8 9.4e-12 44.6 0.7 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KEG12192.1 - 3.7e-14 51.5 8.6 6.3e-06 25.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KEG12192.1 - 1.7e-12 47.4 0.1 9.9e-08 32.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KEG12192.1 - 1.4e-05 24.9 0.5 0.11 12.5 0.0 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KEG12192.1 - 0.00037 20.8 0.3 0.19 12.1 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain SUB1_ProdP9 PF18213.1 KEG12192.1 - 0.018 14.9 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF853 PF05872.12 KEG12192.1 - 0.069 11.7 0.2 3.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) MgtE_N PF03448.17 KEG12192.1 - 0.072 13.7 2.8 1 10.0 0.7 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain SurA_N_3 PF13624.6 KEG12192.1 - 0.083 12.7 1.2 0.31 10.8 0.3 2.0 2 0 0 2 2 2 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 KEG12192.1 - 0.11 12.8 0.1 1.2 9.4 0.2 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 KEG12192.1 - 0.13 12.2 0.1 7.9 6.4 0.0 2.6 2 1 1 3 3 3 0 Caleosin related protein DUF3008 PF11450.8 KEG12192.1 - 0.26 11.5 0.2 0.26 11.5 0.2 2.3 4 0 0 4 4 3 0 Protein of unknwon function (DUF3008) DUF5486 PF17588.2 KEG12192.1 - 1.8 8.5 4.8 2.5 8.0 0.4 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5486) PAP_assoc PF03828.19 KEG12193.1 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEG12193.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF2955 PF11168.8 KEG12193.1 - 0.19 11.6 0.1 0.61 9.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) SR-25 PF10500.9 KEG12193.1 - 0.94 9.0 21.8 0.14 11.8 17.4 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 KEG12193.1 - 1 9.7 19.2 0.037 14.3 12.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4692 PF15763.5 KEG12193.1 - 5.3 7.5 8.1 14 6.2 8.1 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FlgD PF03963.14 KEG12193.1 - 6.5 7.1 8.8 3.5 8.0 0.1 2.8 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region MSA-2c PF12238.8 KEG12193.1 - 7.6 6.5 7.5 18 5.2 7.5 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Peptidase_S24 PF00717.23 KEG12195.1 - 1e-09 38.2 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like SET PF00856.28 KEG12196.1 - 1.6e-12 48.1 0.4 4.8e-11 43.3 0.4 2.3 1 1 0 1 1 1 1 SET domain Glycos_transf_2 PF00535.26 KEG12197.1 - 4.1e-30 104.8 0.0 5.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEG12197.1 - 1.1e-09 38.6 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEG12197.1 - 0.00066 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KEG12197.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KEG12197.1 - 0.2 11.1 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FKBP_C PF00254.28 KEG12198.1 - 1.2e-26 92.9 0.0 1.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sugarporin_N PF11471.8 KEG12199.1 - 0.052 13.5 10.0 0.64 10.0 0.6 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension ADIP PF11559.8 KEG12199.1 - 0.11 12.5 16.8 0.047 13.8 14.4 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KEG12199.1 - 0.14 12.0 13.7 1.4 8.8 4.0 2.7 1 1 1 2 2 2 0 Septum formation initiator SF1-HH PF16275.5 KEG12199.1 - 0.16 12.3 6.9 0.9 9.9 0.5 3.3 2 1 1 3 3 3 0 Splicing factor 1 helix-hairpin domain Atg14 PF10186.9 KEG12199.1 - 0.17 10.9 8.5 0.28 10.2 8.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1515 PF07439.11 KEG12199.1 - 0.44 10.6 4.1 0.84 9.7 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4349 PF14257.6 KEG12199.1 - 0.57 9.6 7.8 1.3 8.5 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF641 PF04859.12 KEG12199.1 - 1.2 9.5 13.1 0.35 11.2 5.4 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) OmpH PF03938.14 KEG12199.1 - 1.2 9.5 7.4 2.5 8.5 7.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nup88 PF10168.9 KEG12199.1 - 1.5 6.5 9.1 2.1 6.1 9.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Fungal_TACC PF12709.7 KEG12199.1 - 2 8.9 7.7 6.9 7.2 1.1 2.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins GIT_CC PF16559.5 KEG12199.1 - 2.5 8.0 8.2 0.41 10.6 2.4 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Exonuc_VII_L PF02601.15 KEG12199.1 - 3.5 7.1 12.1 4.3 6.8 11.6 1.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fez1 PF06818.15 KEG12199.1 - 4.5 7.7 20.1 0.75 10.2 14.8 2.0 2 0 0 2 2 2 0 Fez1 Csm1_N PF18504.1 KEG12199.1 - 8.8 6.7 12.1 0.22 11.9 2.9 2.7 2 1 1 3 3 2 0 Csm1 N-terminal domain CENP-Q PF13094.6 KEG12199.1 - 9.4 6.4 19.4 4.1 7.6 14.8 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SLX9 PF15341.6 KEG12199.1 - 9.8 6.6 12.3 18 5.7 12.3 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Paf67 PF10255.9 KEG12200.1 - 1e-52 179.5 0.0 1.6e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KEG12200.1 - 0.0095 16.0 0.0 0.25 11.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF569 PF04601.13 KEG12200.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF569) FGGY_N PF00370.21 KEG12201.1 - 2e-76 256.8 0.0 2.6e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KEG12201.1 - 7.2e-32 110.7 0.6 1.2e-31 110.0 0.6 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KEG12201.1 - 0.0038 16.7 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Rbsn PF11464.8 KEG12201.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain HSP70 PF00012.20 KEG12201.1 - 0.44 8.7 1.6 11 4.1 0.6 2.0 2 0 0 2 2 2 0 Hsp70 protein CH PF00307.31 KEG12202.1 - 4.4e-07 30.0 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF1382 PF07131.11 KEG12202.1 - 1.4 9.0 4.3 6.7 6.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1382) TFIIS_M PF07500.14 KEG12203.1 - 0.013 16.0 0.3 0.049 14.1 0.3 1.9 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Ank_2 PF12796.7 KEG12204.1 - 0.012 16.2 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF2939 PF11159.8 KEG12204.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) NUDIX PF00293.28 KEG12205.1 - 2.1e-12 47.2 0.0 3.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Dynein_light PF01221.18 KEG12206.1 - 2.2e-24 85.6 1.7 2.5e-24 85.4 1.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4085 PF13315.6 KEG12206.1 - 0.0022 17.6 0.8 0.0029 17.3 0.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4085) DUF4854 PF16146.5 KEG12206.1 - 0.025 14.9 1.1 0.045 14.1 0.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4854) Transglut_prok PF09017.10 KEG12206.1 - 0.062 12.6 0.0 0.062 12.6 0.0 1.0 1 0 0 1 1 1 0 Microbial transglutaminase ESCRT-II PF05871.12 KEG12207.1 - 2.6e-13 50.4 0.0 6.7e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 ESCRT-II complex subunit Proteasome PF00227.26 KEG12208.1 - 1.2e-28 99.9 0.2 1.6e-28 99.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Cob_adeno_trans PF01923.18 KEG12209.1 - 0.019 15.1 1.0 0.019 15.1 1.0 2.2 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Vir_act_alpha_C PF10400.9 KEG12209.1 - 0.12 13.1 7.0 0.63 10.8 0.4 3.4 3 0 0 3 3 3 0 Virulence activator alpha C-term RNase_HII PF01351.18 KEG12210.1 - 1.5e-20 73.9 0.0 3.5e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease HII PI3_PI4_kinase PF00454.27 KEG12211.1 - 1.2e-47 162.9 0.0 2.8e-47 161.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KEG12211.1 - 4.6e-24 85.3 1.8 1.2e-23 83.9 1.8 1.8 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KEG12211.1 - 2.9e-10 39.8 0.2 8e-10 38.4 0.2 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KEG12211.1 - 0.0071 16.5 3.2 14 6.3 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat TFCD_C PF12612.8 KEG12211.1 - 0.01 15.7 4.1 0.011 15.6 0.4 3.1 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 KEG12211.1 - 0.2 12.2 7.4 52 4.5 1.0 5.9 6 0 0 6 6 6 0 HEAT-like repeat MORN PF02493.20 KEG12213.1 - 7.9e-05 22.3 22.8 0.021 14.7 1.2 5.9 6 0 0 6 6 6 3 MORN repeat AAA PF00004.29 KEG12214.1 - 5e-05 23.7 0.0 0.00016 22.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG12214.1 - 0.0021 18.3 0.2 0.27 11.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KEG12214.1 - 0.0024 18.3 4.9 0.0038 17.6 0.1 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEG12214.1 - 0.0026 17.8 0.1 0.65 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEG12214.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KEG12214.1 - 0.21 11.5 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain zf-RING_2 PF13639.6 KEG12215.1 - 0.00021 21.5 1.9 0.00067 19.9 1.9 2.0 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KEG12215.1 - 0.00032 20.3 2.9 0.00032 20.3 2.9 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KEG12215.1 - 0.00046 20.4 6.0 0.0011 19.2 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KEG12215.1 - 0.0035 17.1 1.5 0.012 15.5 1.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG12215.1 - 0.007 16.4 2.7 0.019 15.0 2.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KEG12215.1 - 0.98 9.6 5.0 6 7.1 4.7 2.6 2 1 0 2 2 2 0 Zinc-ribbon like family zf-RING_5 PF14634.6 KEG12215.1 - 2.9 7.9 7.0 32 4.6 7.0 2.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-Mss51 PF13824.6 KEG12215.1 - 4.9 7.3 5.4 1.2 9.3 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 RHSP PF07999.11 KEG12216.1 - 1.7e-98 330.3 0.0 2.5e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.6 KEG12216.1 - 0.0034 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain GDC-P PF02347.16 KEG12217.1 - 5e-175 582.4 0.0 9e-166 552.0 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KEG12217.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.25 KEG12218.1 - 2.2e-62 210.8 0.0 2.5e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12218.1 - 7e-24 84.5 0.0 9.3e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG12218.1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEG12218.1 - 0.052 12.9 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KEG12218.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FYVE PF01363.21 KEG12220.1 - 3e-18 65.7 11.1 4.9e-18 65.0 11.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KEG12220.1 - 0.59 10.3 8.3 2.1 8.6 8.3 2.0 1 1 0 1 1 1 0 AN1-like Zinc finger zf_C2HC_14 PF18574.1 KEG12220.1 - 0.91 9.4 5.0 2.4 8.0 5.0 1.7 1 0 0 1 1 1 0 C2HC Zing finger domain PPV_E1_N PF00524.18 KEG12221.1 - 0.064 13.7 0.7 0.064 13.7 0.7 1.8 2 0 0 2 2 2 0 E1 Protein, N terminal domain Actin PF00022.19 KEG12222.1 - 0.0021 16.7 0.0 0.013 14.1 0.1 2.1 3 0 0 3 3 3 1 Actin Peptidase_A21 PF03566.13 KEG12223.1 - 0.34 9.1 4.0 0.34 9.1 4.0 1.0 1 0 0 1 1 1 0 Peptidase family A21 Glyco_hydro_71 PF03659.14 KEG12224.1 - 0.094 11.5 0.0 0.43 9.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 71 Rhomboid PF01694.22 KEG12225.1 - 0.083 12.9 6.9 0.049 13.6 4.2 2.1 2 1 0 2 2 2 0 Rhomboid family Pribosyltran PF00156.27 KEG12226.1 - 6e-20 71.4 0.0 8.2e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEG12226.1 - 0.017 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KEG12226.1 - 0.038 13.5 0.2 0.078 12.5 0.1 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase Pribosyltran PF00156.27 KEG12227.1 - 1.2e-17 63.9 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEG12227.1 - 0.00053 19.5 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KEG12227.1 - 0.061 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase MCM_bind PF09739.9 KEG12228.1 - 9.6e-39 133.3 0.0 1.4e-37 129.4 0.0 2.1 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor MHCassoc_trimer PF08831.10 KEG12229.1 - 0.081 13.0 0.7 0.4 10.7 0.3 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Baculo_p24 PF05073.12 KEG12229.1 - 0.3 10.8 2.1 0.81 9.5 1.5 2.0 1 1 0 1 1 1 0 Baculovirus P24 capsid protein WXG100 PF06013.12 KEG12229.1 - 0.69 10.2 4.2 0.69 10.2 0.4 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG PIN_9 PF18477.1 KEG12229.1 - 1.2 9.4 5.3 3.5 8.0 0.0 3.4 2 1 1 3 3 3 0 PIN like domain betaPIX_CC PF16523.5 KEG12229.1 - 4 7.3 9.8 0.91 9.4 2.9 2.6 1 1 1 2 2 2 0 betaPIX coiled coil YabA PF06156.13 KEG12229.1 - 5.5 7.7 14.1 2.3 8.9 4.2 3.7 2 1 2 4 4 4 0 Initiation control protein YabA NIF PF03031.18 KEG12230.1 - 3.9e-49 166.4 0.0 5.4e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L30 PF00327.20 KEG12231.1 - 5.3e-19 67.8 2.8 5.8e-19 67.7 1.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 KEG12231.1 - 2.5e-17 62.9 11.0 4.5e-17 62.1 11.0 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain BUD22 PF09073.10 KEG12232.1 - 0.005 16.2 3.8 0.0061 15.9 3.8 1.1 1 0 0 1 1 1 1 BUD22 DASH_Spc19 PF08287.11 KEG12232.1 - 0.028 14.3 5.3 0.055 13.4 4.2 1.8 2 0 0 2 2 2 0 Spc19 LNS2 PF08235.13 KEG12233.1 - 1.1e-85 286.8 0.0 1.5e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KEG12233.1 - 1.8e-20 72.8 0.0 4.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Spt20 PF12090.8 KEG12233.1 - 0.47 10.0 10.2 1.2 8.7 10.2 1.6 1 0 0 1 1 1 0 Spt20 family FAM92 PF06730.11 KEG12234.1 - 0.013 14.9 0.5 0.03 13.8 0.5 1.5 1 0 0 1 1 1 0 FAM92 protein Mis12 PF05859.12 KEG12234.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.7 1 1 0 1 1 1 0 Mis12 protein Tho1_MOS11_C PF18592.1 KEG12234.1 - 0.25 11.2 2.9 15 5.5 0.1 2.6 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain FTA4 PF13093.6 KEG12234.1 - 0.52 10.2 6.2 2.3 8.1 6.2 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 KEG12234.1 - 1.2 8.4 6.0 9.1 5.6 0.6 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5596 PF18082.1 KEG12235.1 - 0.067 13.0 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) Pentapeptide_2 PF01469.18 KEG12237.1 - 0.00084 19.2 13.9 0.06 13.2 13.9 2.7 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) GpcrRhopsn4 PF10192.9 KEG12239.1 - 0.032 13.6 1.6 0.07 12.5 1.6 1.5 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain RWD PF05773.22 KEG12241.1 - 5.1e-07 30.0 0.1 8.5e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KEG12241.1 - 0.00021 21.7 5.6 0.00078 19.9 5.6 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF1722 PF08349.11 KEG12241.1 - 0.071 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Hva1_TUDOR PF11160.8 KEG12242.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.5 2 0 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain MORN PF02493.20 KEG12243.1 - 3.7e-20 70.5 31.8 2.5e-05 23.9 0.5 9.6 10 0 0 10 10 10 7 MORN repeat WW PF00397.26 KEG12243.1 - 0.031 14.4 0.7 0.068 13.3 0.0 1.9 2 0 0 2 2 2 0 WW domain Ribosomal_S15 PF00312.22 KEG12244.1 - 9.6e-06 25.7 1.2 2e-05 24.7 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 CTP_transf_like PF01467.26 KEG12245.1 - 0.00032 20.9 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like DNA_RNApol_7kD PF03604.13 KEG12246.1 - 9.3e-06 25.2 0.3 1.6e-05 24.4 0.3 1.5 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 KEG12246.1 - 0.2 11.4 1.9 4.1 7.2 0.1 2.1 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PPR_2 PF13041.6 KEG12247.1 - 6.2e-12 45.5 0.0 0.0035 17.5 0.0 4.6 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.20 KEG12247.1 - 1.6e-08 34.2 0.0 0.032 14.5 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 KEG12247.1 - 0.014 15.4 0.2 8.9 6.5 0.0 3.3 2 1 1 4 4 4 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 KEG12247.1 - 0.066 12.9 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 PPR repeat PPR_long PF17177.4 KEG12247.1 - 0.12 11.7 1.0 2.3 7.5 0.0 2.3 1 1 2 3 3 3 0 Pentacotripeptide-repeat region of PRORP Tubulin PF00091.25 KEG12248.1 - 5.9e-32 111.5 0.0 2.4e-16 60.5 0.0 3.1 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KEG12248.1 - 0.0002 20.6 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin like TM231 PF10149.9 KEG12249.1 - 3.3e-21 75.9 0.2 5.6e-20 71.9 0.2 2.4 1 1 0 1 1 1 1 Transmembrane protein 231 DAO PF01266.24 KEG12250.1 - 4.7e-25 88.9 3.9 7.4e-25 88.3 3.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEG12250.1 - 1.4e-12 47.6 0.7 3.6e-11 43.0 0.5 2.6 1 1 1 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase HI0933_like PF03486.14 KEG12250.1 - 1.9e-05 23.6 0.7 2.7e-05 23.1 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KEG12250.1 - 9.2e-05 21.7 5.4 9.2e-05 21.7 5.4 2.2 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEG12250.1 - 0.00025 21.2 0.2 0.0007 19.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEG12250.1 - 0.00043 19.6 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEG12250.1 - 0.00066 19.1 2.2 0.001 18.5 2.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEG12250.1 - 0.012 15.0 0.3 0.025 13.9 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KEG12250.1 - 0.015 14.5 0.2 0.025 13.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KEG12250.1 - 0.034 14.7 0.6 0.31 11.6 0.8 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG12250.1 - 0.035 13.4 0.3 0.052 12.8 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KEG12250.1 - 0.044 13.4 0.8 0.085 12.4 0.8 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KEG12250.1 - 0.049 14.1 0.1 0.13 12.7 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KEG12250.1 - 0.14 11.2 1.2 0.21 10.6 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KEG12250.1 - 0.17 11.1 1.0 0.26 10.5 0.3 1.6 2 0 0 2 2 2 0 Thi4 family Methyltransf_8 PF05148.15 KEG12251.1 - 2e-52 178.2 0.0 2.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KEG12251.1 - 9.7e-08 32.6 0.1 5e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG12251.1 - 6.3e-06 26.8 0.1 0.00061 20.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEG12251.1 - 0.00088 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEG12251.1 - 0.016 15.0 0.0 0.046 13.6 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Fez1 PF06818.15 KEG12252.1 - 0.011 16.3 2.5 0.011 16.3 2.5 4.4 2 1 2 4 4 4 0 Fez1 Connexin50 PF03509.14 KEG12252.1 - 0.57 11.0 2.8 2.9 8.8 0.0 3.3 3 1 0 3 3 3 0 Gap junction alpha-8 protein (Cx50) Spc7 PF08317.11 KEG12252.1 - 0.75 8.6 89.6 0.11 11.3 23.3 4.5 1 1 3 4 4 4 0 Spc7 kinetochore protein Tuberculin PF12198.8 KEG12254.1 - 2 8.6 5.8 5.1 7.3 5.8 1.6 1 0 0 1 1 1 0 Theoretical tuberculin protein PSP1 PF04468.12 KEG12255.1 - 1.1e-29 102.5 0.2 1.8e-29 101.8 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NIF3 PF01784.18 KEG12256.1 - 3.7e-65 220.0 0.0 4.4e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DNA_pol_D_N PF18018.1 KEG12256.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Trp_leader1 PF08055.11 KEG12257.1 - 0.8 9.5 4.8 1.5 8.6 4.8 1.4 1 0 0 1 1 1 0 Tryptophan leader peptide Pkinase PF00069.25 KEG12258.1 - 1.5e-51 175.3 0.0 1.9e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12258.1 - 1.9e-25 89.6 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG12258.1 - 5.3e-06 26.5 0.0 2.1e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG12258.1 - 4.3e-05 23.0 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEG12258.1 - 0.0025 16.8 0.0 0.0048 15.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KEG12258.1 - 0.0036 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KEG12258.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KEG12258.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEG12258.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KEG12258.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase tRNA-synt_2b PF00587.25 KEG12259.1 - 1.7e-29 103.1 0.0 2.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KEG12259.1 - 4.1e-19 68.8 1.7 6.6e-15 55.3 0.2 2.5 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain MORN PF02493.20 KEG12260.1 - 6.7e-51 167.2 63.2 5e-09 35.5 0.2 10.6 10 0 0 10 10 10 10 MORN repeat DUF523 PF04463.12 KEG12260.1 - 0.063 13.3 0.9 7.5 6.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF523) RRM_1 PF00076.22 KEG12261.1 - 0.0001 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRIP PF01465.20 KEG12262.1 - 2.5e-15 56.1 0.1 6.7e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Filament PF00038.21 KEG12262.1 - 4.2e-05 23.3 4.2 4.2e-05 23.3 4.2 7.7 3 1 4 7 7 7 1 Intermediate filament protein Seryl_tRNA_N PF02403.22 KEG12262.1 - 0.0024 18.1 2.3 0.0024 18.1 2.3 8.4 6 3 2 8 8 8 3 Seryl-tRNA synthetase N-terminal domain Val_tRNA-synt_C PF10458.9 KEG12262.1 - 0.0029 17.8 5.5 0.0029 17.8 5.5 6.6 7 3 0 8 8 8 1 Valyl tRNA synthetase tRNA binding arm CtIP_N PF10482.9 KEG12262.1 - 0.034 14.2 0.2 0.034 14.2 0.2 6.8 6 1 1 7 7 7 0 Tumour-suppressor protein CtIP N-terminal domain Prp19 PF08606.11 KEG12262.1 - 0.18 11.8 13.9 1.2 9.2 0.2 5.1 4 0 0 4 4 4 0 Prp19/Pso4-like V-ATPase_H_C PF11698.8 KEG12262.1 - 8.3 6.5 13.1 2.5 8.2 0.2 4.4 4 0 0 4 4 4 0 V-ATPase subunit H Pkinase PF00069.25 KEG12263.1 - 2.9e-40 138.3 0.1 2.3e-26 92.8 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12263.1 - 4.2e-15 55.7 0.5 3.2e-08 33.2 0.4 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 KEG12263.1 - 2.1e-06 28.0 0.0 6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KEG12263.1 - 0.0013 18.7 0.1 0.0033 17.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG12263.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEG12263.1 - 0.068 12.5 0.0 0.27 10.5 0.0 2.0 1 1 0 1 1 1 0 Kinase-like TFIIF_alpha PF05793.12 KEG12263.1 - 0.37 9.3 4.9 0.56 8.7 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 KEG12263.1 - 0.76 9.8 4.7 1.3 9.1 4.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SNF2_N PF00176.23 KEG12264.1 - 3.3e-27 95.1 0.2 5.3e-27 94.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG12264.1 - 3.2e-09 37.1 0.0 6.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH PF01844.23 KEG12264.1 - 3.3e-08 33.6 0.3 1.7e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 KEG12264.1 - 0.00011 21.9 3.1 0.00013 21.8 0.1 2.6 3 0 0 3 3 3 1 HNH endonuclease ABC_tran PF00005.27 KEG12265.1 - 1.4e-28 100.1 0.0 2.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG12265.1 - 2.7e-05 24.2 0.5 0.024 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG12265.1 - 0.00017 21.1 0.9 0.0062 16.0 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEG12265.1 - 0.0017 18.3 0.1 0.0034 17.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 KEG12265.1 - 0.0048 17.1 0.9 0.04 14.2 0.1 2.5 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KEG12265.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEG12265.1 - 0.044 14.2 0.1 0.072 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEG12265.1 - 0.071 13.4 1.3 0.26 11.5 0.1 2.2 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 KEG12265.1 - 0.19 12.2 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KEG12265.1 - 0.19 12.0 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KEG12265.1 - 0.6 8.8 3.3 14 4.3 0.3 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class Hexapep PF00132.24 KEG12266.1 - 2.3e-10 39.8 0.5 0.00012 21.6 0.1 3.5 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEG12266.1 - 0.46 10.3 2.2 18 5.2 0.1 3.0 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase COPIIcoated_ERV PF07970.12 KEG12267.1 - 1.4e-41 142.7 0.2 2.4e-41 142.0 0.1 1.4 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KEG12267.1 - 1.5e-24 86.1 0.3 8.8e-24 83.7 0.0 2.2 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HALZ PF02183.18 KEG12268.1 - 0.032 14.5 1.6 0.032 14.5 1.6 3.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF4375 PF14300.6 KEG12268.1 - 4.1 7.7 7.1 0.42 10.9 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) DUF4337 PF14235.6 KEG12268.1 - 4.8 7.3 11.1 8.1 6.5 2.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) THF_DHG_CYH_C PF02882.19 KEG12269.1 - 1.5e-61 206.4 0.3 2e-61 206.0 0.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KEG12269.1 - 8.4e-36 122.8 0.1 1.2e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.23 KEG12270.1 - 1.8e-29 102.1 0.4 3.7e-29 101.0 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain IU_nuc_hydro PF01156.19 KEG12271.1 - 2.4e-13 50.3 0.1 3.2e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vps52 PF04129.12 KEG12272.1 - 1.6e-56 192.1 0.0 4.1e-20 72.0 0.0 3.1 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.9 KEG12272.1 - 0.016 13.7 0.0 1.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec3 TPR_2 PF07719.17 KEG12274.1 - 1.1e-51 168.8 41.5 0.0013 18.6 0.0 16.8 16 1 1 17 17 17 14 Tetratricopeptide repeat TPR_1 PF00515.28 KEG12274.1 - 5.4e-41 136.8 30.8 0.00018 21.2 0.0 16.2 15 1 0 15 15 15 11 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12274.1 - 1.7e-32 108.9 18.6 0.049 13.9 0.0 13.9 15 0 0 15 15 13 10 Tetratricopeptide repeat TPR_16 PF13432.6 KEG12274.1 - 9.3e-31 106.2 36.1 2.5e-05 24.8 3.5 10.1 6 3 5 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12274.1 - 3.3e-27 93.9 26.6 9.5e-07 28.4 0.0 12.0 8 4 4 12 12 12 7 TPR repeat TPR_9 PF13371.6 KEG12274.1 - 1.8e-23 82.4 30.6 3.2e-05 24.0 0.1 10.3 5 4 5 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 KEG12274.1 - 1.7e-18 66.7 49.9 1.3e-05 25.4 0.0 11.1 7 4 5 12 12 12 7 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12274.1 - 2.7e-14 52.7 28.2 0.083 13.7 0.2 12.8 9 4 5 14 14 13 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG12274.1 - 6e-11 42.7 26.1 0.016 15.7 1.2 8.3 7 1 2 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG12274.1 - 7e-09 35.8 32.3 0.00013 22.1 5.0 6.9 4 3 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KEG12274.1 - 1e-07 32.1 25.5 1.1 10.1 0.1 11.4 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG12274.1 - 1.2e-07 31.6 30.2 0.096 13.1 0.5 11.6 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_20 PF14561.6 KEG12274.1 - 6.4e-07 29.6 11.4 0.44 10.9 0.3 5.9 6 1 1 7 7 6 3 Tetratricopeptide repeat BTAD PF03704.17 KEG12274.1 - 2.7e-05 24.6 22.8 0.076 13.5 0.4 7.2 4 2 3 9 9 9 3 Bacterial transcriptional activator domain TPR_10 PF13374.6 KEG12274.1 - 0.00018 21.2 30.1 0.91 9.5 0.0 10.9 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG12274.1 - 0.0049 16.8 26.5 0.98 9.6 0.1 9.3 11 0 0 11 11 11 1 Tetratricopeptide repeat T3SS_basalb_I PF17001.5 KEG12274.1 - 0.081 13.5 0.1 27 5.4 0.0 3.3 3 0 0 3 3 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI NARP1 PF12569.8 KEG12274.1 - 0.17 10.7 1.7 35 3.1 0.0 3.8 3 1 1 5 5 5 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KEG12274.1 - 3.6 8.5 28.8 0.84 10.5 0.6 8.7 10 0 0 10 10 7 0 Tetratricopeptide repeat Ret2_MD PF18528.1 KEG12275.1 - 7.2e-52 173.7 0.5 1.2e-51 173.0 0.5 1.4 1 0 0 1 1 1 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PAP_assoc PF03828.19 KEG12275.1 - 2.2e-17 63.0 0.3 4.5e-17 62.0 0.3 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEG12275.1 - 0.00041 20.6 0.0 0.0008 19.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SNase PF00565.17 KEG12276.1 - 0.0035 17.8 0.0 0.0057 17.1 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue 2OG-FeII_Oxy_2 PF13532.6 KEG12277.1 - 9.9e-11 42.2 0.0 1.3e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_Tnp_IS1595 PF12760.7 KEG12278.1 - 0.0075 16.2 3.3 0.0075 16.2 3.3 2.9 1 1 2 3 3 3 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 KEG12278.1 - 0.07 13.6 0.5 0.07 13.6 0.5 2.9 2 1 1 3 3 3 0 Zinc-finger double domain zf-B_box PF00643.24 KEG12278.1 - 3.9 7.7 21.3 0.63 10.2 9.2 2.9 2 1 1 3 3 3 0 B-box zinc finger PseudoU_synth_1 PF01416.20 KEG12279.1 - 4.2e-09 36.8 0.0 2.6e-07 31.1 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase Raftlin PF15250.6 KEG12279.1 - 1 8.0 5.3 1.5 7.5 5.3 1.1 1 0 0 1 1 1 0 Raftlin ParA PF10609.9 KEG12280.1 - 1.3e-94 316.3 0.0 1.6e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEG12280.1 - 1.8e-10 40.9 0.0 7.3e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEG12280.1 - 2.1e-07 31.0 2.1 2.8e-06 27.4 2.1 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KEG12280.1 - 1.3e-06 27.9 0.4 0.00013 21.3 0.3 2.2 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 KEG12280.1 - 5.1e-06 25.9 1.1 2.2e-05 23.8 0.5 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KEG12280.1 - 0.00033 20.3 0.4 0.0011 18.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 KEG12280.1 - 0.0093 15.4 0.2 0.02 14.4 0.1 1.5 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 KEG12280.1 - 0.011 15.0 0.3 0.019 14.1 0.3 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KEG12280.1 - 0.029 14.3 0.4 0.065 13.2 0.4 1.5 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 KEG12280.1 - 0.055 12.4 0.6 0.092 11.7 0.6 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KEG12280.1 - 0.082 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CBP_BcsQ PF06564.12 KEG12280.1 - 0.2 11.1 0.4 0.41 10.1 0.4 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ DUF1358 PF07096.11 KEG12281.1 - 9.6e-05 22.4 0.7 0.00017 21.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) KNTase_C PF07827.11 KEG12281.1 - 0.047 13.5 0.1 0.055 13.3 0.1 1.4 1 1 0 1 1 1 0 KNTase C-terminal domain Porin_3 PF01459.22 KEG12282.1 - 0.0028 17.2 0.1 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic porin AAA_33 PF13671.6 KEG12283.1 - 2.4e-10 40.7 0.0 3.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEG12283.1 - 3.4e-06 26.7 0.0 4.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KEG12283.1 - 1.5e-05 24.4 0.0 4.8e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KEG12283.1 - 0.00017 22.2 0.0 0.00027 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KEG12283.1 - 0.00049 19.5 0.0 0.00097 18.5 0.0 1.4 1 1 0 1 1 1 1 KaiC AAA_5 PF07728.14 KEG12283.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KEG12283.1 - 0.00078 19.9 0.2 0.0032 17.9 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEG12283.1 - 0.0011 19.3 0.0 0.0019 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEG12283.1 - 0.0013 19.2 0.1 0.0062 17.0 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1201 PF06716.11 KEG12283.1 - 0.0023 17.9 0.2 0.0042 17.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) AAA_22 PF13401.6 KEG12283.1 - 0.0038 17.5 0.1 0.012 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEG12283.1 - 0.0038 16.9 0.0 0.0099 15.5 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KEG12283.1 - 0.0045 16.7 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KEG12283.1 - 0.0069 16.3 0.0 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KEG12283.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KEG12283.1 - 0.021 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 KEG12283.1 - 0.028 14.5 0.3 1.6 8.8 0.2 2.1 1 1 0 1 1 1 0 Adenylate kinase CPT PF07931.12 KEG12283.1 - 0.042 13.7 0.2 0.22 11.4 0.2 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KEG12283.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KEG12283.1 - 0.065 12.4 0.1 0.093 11.9 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit cobW PF02492.19 KEG12283.1 - 0.08 12.5 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PEPCK_ATP PF01293.20 KEG12283.1 - 0.13 10.9 0.2 5.2 5.6 0.0 2.0 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxykinase DUF4040 PF13244.6 KEG12283.1 - 0.28 11.4 2.0 0.46 10.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) WW PF00397.26 KEG12285.1 - 1.9e-05 24.7 6.0 3.3e-05 23.9 6.0 1.4 1 0 0 1 1 1 1 WW domain eIF3g PF12353.8 KEG12285.1 - 0.00018 21.9 15.2 0.0019 18.6 0.8 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 KEG12285.1 - 0.00026 20.9 1.1 0.00026 20.9 1.1 3.4 4 1 0 4 4 4 1 Zinc knuckle zf-CCHC_2 PF13696.6 KEG12285.1 - 0.0086 15.9 10.5 0.34 10.8 2.8 3.2 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KEG12285.1 - 0.012 15.5 11.0 0.05 13.6 5.3 2.7 2 0 0 2 2 2 0 Zinc knuckle Pap_E4 PF02711.14 KEG12285.1 - 0.16 12.9 10.1 0.58 11.1 1.0 2.9 2 1 1 3 3 3 0 E4 protein HypA PF01155.19 KEG12285.1 - 1.7 8.7 13.7 19 5.3 0.1 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Actino_peptide PF14408.6 KEG12285.1 - 1.9 8.7 5.0 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes SR-25 PF10500.9 KEG12285.1 - 8.8 5.9 16.8 3.5 7.2 11.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Drf_FH3 PF06367.16 KEG12287.1 - 0.043 13.4 0.3 0.42 10.2 0.0 2.4 2 0 0 2 2 2 0 Diaphanous FH3 Domain CesT PF05932.13 KEG12288.1 - 9.6e-17 61.2 0.1 2.8e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family ubiquitin PF00240.23 KEG12288.1 - 2.8e-06 27.0 0.3 1.8e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KEG12288.1 - 0.001 18.8 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HIP1_clath_bdg PF16515.5 KEG12288.1 - 0.85 10.3 25.3 0.85 10.3 12.4 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CCDC23 PF15674.5 KEG12288.1 - 1.7 8.7 16.2 8.8 6.4 4.4 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 23 GAS PF13851.6 KEG12288.1 - 3.4 7.0 28.4 0.83 9.0 6.7 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 KEG12288.1 - 6.9 5.4 5.1 11 4.8 5.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Epimerase PF01370.21 KEG12290.1 - 3.6e-18 65.9 0.0 5.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEG12290.1 - 2.1e-10 40.8 0.1 6.1e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEG12290.1 - 1.5e-08 34.4 0.1 8.7e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KEG12290.1 - 5.9e-08 32.6 0.0 1.2e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KEG12290.1 - 2e-07 30.3 0.2 9.7e-07 28.1 0.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AP_endonuc_2 PF01261.24 KEG12290.1 - 0.043 13.2 0.0 0.097 12.1 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Tankyrase_bdg_C PF15327.6 KEG12290.1 - 0.053 14.0 1.0 0.098 13.1 1.0 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain KR PF08659.10 KEG12290.1 - 0.065 13.1 0.8 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 KR domain Pex14_N PF04695.13 KEG12290.1 - 1.5 9.4 7.1 0.13 12.9 0.7 2.5 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KEG12290.1 - 1.8 8.1 10.2 3.7 7.1 10.2 1.4 1 0 0 1 1 1 0 Spt20 family GCV_H PF01597.19 KEG12292.1 - 4.7e-05 23.3 0.0 7.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein 2OG-FeII_Oxy_3 PF13640.6 KEG12293.1 - 0.016 16.1 0.0 0.065 14.1 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PhoLip_ATPase_C PF16212.5 KEG12294.1 - 1.5e-38 133.0 25.3 1.5e-38 133.0 25.3 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 KEG12294.1 - 1.8e-15 56.9 0.8 7.1e-15 55.0 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 KEG12294.1 - 3.1e-15 55.6 0.9 3.1e-15 55.6 0.9 2.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEG12294.1 - 4.8e-11 43.3 1.6 0.00054 20.3 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEG12294.1 - 4.1e-10 39.6 0.0 1.6e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEG12294.1 - 0.0018 18.0 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NPR2 PF06218.11 KEG12295.1 - 0.00027 19.8 0.0 0.019 13.7 0.0 2.3 2 0 0 2 2 2 2 Nitrogen permease regulator 2 PqqD PF05402.12 KEG12295.1 - 0.025 14.9 0.1 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) LRRFIP PF09738.9 KEG12295.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 LRRFIP family Kinesin PF00225.23 KEG12296.1 - 3.2e-94 315.6 1.3 8e-93 311.0 0.1 3.0 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KEG12296.1 - 6.3e-20 71.6 0.0 3.2e-18 66.1 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding Pkinase PF00069.25 KEG12297.1 - 1.1e-52 179.1 0.0 2.9e-52 177.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12297.1 - 2e-36 125.6 0.0 3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG12297.1 - 1e-06 28.3 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG12297.1 - 0.0063 15.3 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG12297.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helicase_C PF00271.31 KEG12298.1 - 5.9e-17 62.0 0.1 1.5e-16 60.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG12298.1 - 6.2e-11 42.4 0.0 1.9e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG12298.1 - 3.5e-10 40.2 0.0 1.6e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KEG12298.1 - 0.0018 18.0 0.1 0.0055 16.4 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase PhoH PF02562.16 KEG12298.1 - 0.043 13.3 0.3 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KEG12298.1 - 0.044 13.5 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KEG12298.1 - 0.062 13.6 0.0 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain EF-hand_6 PF13405.6 KEG12299.1 - 3.9e-18 63.8 2.0 0.0069 16.2 0.0 6.2 6 0 0 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 KEG12299.1 - 7.3e-17 59.6 0.3 0.00011 21.5 0.0 5.6 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 KEG12299.1 - 3.8e-16 59.3 2.5 0.00048 20.5 0.0 4.9 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 KEG12299.1 - 1.2e-13 50.7 3.8 2.4e-05 24.1 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KEG12299.1 - 1.2e-08 34.1 0.1 0.0014 18.1 0.0 5.1 5 0 0 5 5 5 1 EF hand EF-hand_4 PF12763.7 KEG12299.1 - 0.11 12.4 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Phage_TAC_6 PF09550.10 KEG12299.1 - 0.21 12.1 1.9 0.79 10.2 0.1 2.9 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC DUF2953 PF11167.8 KEG12299.1 - 0.28 11.3 2.0 43 4.3 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) AAA PF00004.29 KEG12300.1 - 3.3e-14 53.4 0.0 1.7e-07 31.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG12300.1 - 7e-05 23.3 0.2 0.0004 20.8 0.0 2.2 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEG12300.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG12300.1 - 0.0049 17.2 0.0 0.014 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KEG12300.1 - 0.024 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KEG12300.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KEG12300.1 - 0.04 13.9 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KEG12300.1 - 0.077 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEG12300.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KEG12300.1 - 0.13 12.4 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KEG12300.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Bac_DnaA PF00308.18 KEG12300.1 - 0.22 11.3 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein RRN3 PF05327.11 KEG12300.1 - 0.97 7.9 6.8 1.5 7.3 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 KEG12300.1 - 1.1 8.8 8.4 1.8 8.1 8.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KEG12300.1 - 1.1 7.3 8.6 1.5 6.9 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KEG12300.1 - 1.9 6.5 14.3 2.7 6.0 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 KEG12300.1 - 2.8 7.8 5.7 5.2 6.9 5.5 1.4 2 0 0 2 2 1 0 Sigma-70, non-essential region Histone_H2A_C PF16211.5 KEG12301.1 - 1.2e-10 40.9 0.2 3.5e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KEG12301.1 - 2.6e-06 27.8 0.3 3.5e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEG12301.1 - 0.012 15.9 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Prp18 PF02840.15 KEG12303.1 - 3.7e-14 53.0 0.0 6.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Prp18 domain UL17 PF17640.2 KEG12303.1 - 0.33 11.0 2.2 1 9.4 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized UL17 IQ PF00612.27 KEG12304.1 - 0.00065 19.3 1.2 0.0022 17.6 1.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2087 PF09860.9 KEG12304.1 - 8.6 6.6 8.3 0.65 10.2 0.6 3.3 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2087) S1-P1_nuclease PF02265.16 KEG12305.1 - 7.4e-66 222.5 0.0 8.5e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF2498 PF10692.9 KEG12306.1 - 0.0086 15.9 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2498) Kinesin PF00225.23 KEG12307.1 - 1.5e-84 283.8 0.0 3.3e-84 282.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG12307.1 - 2.5e-19 69.7 0.2 5.9e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KEG12307.1 - 0.073 13.4 3.2 0.24 11.8 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 KEG12307.1 - 0.075 12.8 0.5 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase FtsX_ECD PF18075.1 KEG12307.1 - 0.096 13.3 7.2 1.5 9.5 3.6 2.8 2 0 0 2 2 2 0 FtsX extracellular domain ATPase_2 PF01637.18 KEG12307.1 - 0.11 12.4 5.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sec8_exocyst PF04048.14 KEG12307.1 - 0.27 11.1 4.2 0.79 9.6 2.1 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4284 PF14112.6 KEG12307.1 - 0.28 12.1 2.3 27 5.7 0.0 3.1 3 0 0 3 3 3 0 Immunity protein 22 AAA_13 PF13166.6 KEG12307.1 - 0.53 8.9 11.1 1 7.9 11.1 1.5 1 0 0 1 1 1 0 AAA domain DUF5398 PF17376.2 KEG12307.1 - 0.98 10.1 7.4 2.3 8.9 6.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5398) PSP1 PF04468.12 KEG12309.1 - 4e-09 36.6 0.2 7e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RIO1 PF01163.22 KEG12310.1 - 3.5e-45 153.9 0.0 6.6e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KEG12310.1 - 1.8e-31 108.2 0.2 4.2e-31 107.0 0.2 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KEG12310.1 - 1.7e-12 47.8 0.2 8.4e-07 29.1 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEG12310.1 - 0.00046 19.6 4.8 0.00086 18.7 0.1 3.1 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.19 KEG12310.1 - 0.44 11.2 7.7 1.1 9.8 7.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein GRIN_C PF15235.6 KEG12310.1 - 1 9.6 9.4 1.9 8.7 9.1 1.6 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus SpoIIIAH PF12685.7 KEG12310.1 - 4.7 7.0 11.9 8.2 6.2 11.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF755 PF05501.11 KEG12310.1 - 9.1 6.6 7.4 18 5.6 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RabGAP-TBC PF00566.18 KEG12311.1 - 4.9e-39 134.2 1.7 8.1e-39 133.5 0.6 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tom5 PF10642.9 KEG12312.1 - 0.19 11.8 0.9 0.42 10.7 0.9 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase ABC_tran PF00005.27 KEG12313.1 - 1.1e-33 116.7 0.5 4.5e-18 66.1 0.0 3.3 3 0 0 3 3 3 3 ABC transporter AAA_29 PF13555.6 KEG12313.1 - 5.4e-11 42.1 0.2 7.7e-05 22.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEG12313.1 - 1.1e-09 38.5 5.9 0.00042 20.2 0.8 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG12313.1 - 8.6e-09 35.1 1.1 0.19 11.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEG12313.1 - 3.2e-07 30.4 0.2 0.0049 16.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEG12313.1 - 6e-07 30.0 3.3 0.00087 19.7 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KEG12313.1 - 1.4e-06 28.5 0.1 0.0045 17.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KEG12313.1 - 2.2e-06 28.3 0.0 0.09 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEG12313.1 - 2.5e-05 24.6 3.5 0.3 11.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KEG12313.1 - 7.1e-05 22.9 1.4 0.32 11.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SRP54 PF00448.22 KEG12313.1 - 0.00016 21.3 0.6 0.034 13.8 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KEG12313.1 - 0.00017 21.4 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KEG12313.1 - 0.00021 21.4 1.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.12 KEG12313.1 - 0.00022 20.6 0.1 0.27 10.5 0.1 2.2 2 0 0 2 2 2 2 Zeta toxin G-alpha PF00503.20 KEG12313.1 - 0.00045 19.5 0.3 0.23 10.6 0.1 2.5 2 1 1 3 3 3 1 G-protein alpha subunit IstB_IS21 PF01695.17 KEG12313.1 - 0.00049 19.9 0.5 5 6.8 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_24 PF13479.6 KEG12313.1 - 0.00063 19.5 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arf PF00025.21 KEG12313.1 - 0.00092 18.7 0.1 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KEG12313.1 - 0.001 19.3 0.2 1.1 9.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KEG12313.1 - 0.001 18.5 0.1 0.73 9.1 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 KEG12313.1 - 0.001 18.7 0.0 0.67 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEG12313.1 - 0.0012 18.5 0.1 0.11 12.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 KEG12313.1 - 0.0013 18.4 0.4 0.8 9.3 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KEG12313.1 - 0.0017 17.9 0.1 1.8 8.0 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region DLIC PF05783.11 KEG12313.1 - 0.0036 16.2 0.2 0.041 12.7 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_18 PF13238.6 KEG12313.1 - 0.0037 17.8 0.0 0.87 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEG12313.1 - 0.0052 16.7 5.0 0.19 11.6 0.1 3.6 4 0 0 4 4 4 1 NACHT domain ATP-synt_ab PF00006.25 KEG12313.1 - 0.0068 16.1 0.0 0.93 9.1 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 KEG12313.1 - 0.0082 16.4 0.1 2.4 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KEG12313.1 - 0.0082 15.8 0.1 4.1 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 KEG12313.1 - 0.012 14.9 0.4 0.74 9.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family MeaB PF03308.16 KEG12313.1 - 0.015 14.3 0.4 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 KEG12313.1 - 0.017 14.2 0.2 4.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.18 KEG12313.1 - 0.024 13.9 0.1 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 KEG12313.1 - 0.027 14.9 0.2 11 6.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KEG12313.1 - 0.028 13.6 0.7 3.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KEG12313.1 - 0.053 13.2 0.3 16 5.1 0.1 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.14 KEG12313.1 - 0.053 13.5 0.2 2.2 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 KEG12313.1 - 0.063 12.4 1.1 4 6.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 RuvB_N PF05496.12 KEG12313.1 - 0.066 13.0 0.1 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain VirE PF05272.11 KEG12313.1 - 0.067 12.9 0.0 0.94 9.2 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E DUF3584 PF12128.8 KEG12313.1 - 0.07 10.6 2.9 1.7 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 KEG12313.1 - 0.076 12.8 0.1 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ploopntkinase1 PF18748.1 KEG12313.1 - 0.082 12.4 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 APS_kinase PF01583.20 KEG12313.1 - 0.1 12.5 0.4 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 KEG12313.1 - 0.11 12.5 0.5 22 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KEG12313.1 - 0.16 11.8 0.2 7.3 6.4 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KEG12313.1 - 0.17 11.7 1.2 3.3 7.4 0.2 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KEG12313.1 - 0.18 12.2 0.1 32 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MutS_V PF00488.21 KEG12313.1 - 0.18 11.8 1.2 54 3.7 0.1 3.3 3 0 0 3 3 3 0 MutS domain V SbcCD_C PF13558.6 KEG12313.1 - 0.29 11.4 1.7 5.7 7.2 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3123 PF11321.8 KEG12314.1 - 0.05 14.3 3.8 15 6.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) Ribosomal_60s PF00428.19 KEG12314.1 - 0.22 12.2 10.1 0.51 11.0 0.8 3.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein TPR_14 PF13428.6 KEG12316.1 - 0.00026 21.6 0.2 6.5 7.9 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KEG12316.1 - 0.018 14.2 1.7 0.057 12.5 0.1 2.7 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference Thioredoxin_13 PF18401.1 KEG12316.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain AAA_22 PF13401.6 KEG12317.1 - 0.026 14.8 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG12317.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.9 KEG12318.1 - 0.14 11.0 0.5 0.21 10.4 0.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UbiA PF01040.18 KEG12319.1 - 1.4e-47 162.1 18.8 2e-47 161.6 18.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family V_ATPase_I PF01496.19 KEG12320.1 - 5e-258 858.3 20.8 3.7e-175 584.2 0.2 3.0 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family Prefoldin_3 PF13758.6 KEG12320.1 - 0.15 12.1 0.9 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit LXG PF04740.12 KEG12320.1 - 0.19 11.4 5.1 0.16 11.7 0.9 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily She9_MDM33 PF05546.11 KEG12320.1 - 0.22 11.3 3.6 0.087 12.6 0.6 1.8 2 0 0 2 2 2 0 She9 / Mdm33 family TolA_bind_tri PF16331.5 KEG12320.1 - 0.45 10.6 11.1 0.53 10.4 1.2 3.7 4 0 0 4 4 4 0 TolA binding protein trimerisation DegS PF05384.11 KEG12320.1 - 1.1 8.7 11.1 5.8 6.4 0.6 3.5 3 0 0 3 3 3 0 Sensor protein DegS CENP-H PF05837.12 KEG12320.1 - 1.5 9.3 5.1 6.6 7.2 0.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) LRR_8 PF13855.6 KEG12322.1 - 3.1e-12 46.1 2.4 0.0072 16.1 1.3 4.6 4 1 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KEG12322.1 - 2.5e-11 43.6 3.0 0.0069 16.8 2.3 5.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG12322.1 - 1.3e-06 28.1 6.8 1.1 10.0 2.1 5.8 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 KEG12322.1 - 4.4e-06 26.3 3.5 0.43 10.8 0.4 5.9 7 0 0 7 7 7 2 Leucine Rich repeat Ala_racemase_N PF01168.20 KEG12323.1 - 7.1e-22 78.1 0.0 8.5e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_4 PF12799.7 KEG12324.1 - 7.5e-07 29.4 0.0 0.0039 17.6 0.0 3.2 1 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG12324.1 - 2.3e-05 24.0 0.0 4.6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KEG12324.1 - 0.029 14.2 0.1 0.97 9.3 0.1 2.7 2 2 0 2 2 2 0 Leucine rich repeat Sulfate_transp PF00916.20 KEG12325.1 - 2.5e-48 164.7 24.0 2.5e-48 164.7 24.0 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEG12325.1 - 2.1e-06 27.4 0.0 4.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain TIP41 PF04176.13 KEG12326.1 - 4.8e-24 84.8 0.2 9.6e-24 83.8 0.0 1.5 2 0 0 2 2 2 1 TIP41-like family GAF_2 PF13185.6 KEG12326.1 - 6.3e-10 39.5 0.0 2.1e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KEG12326.1 - 1.6e-06 28.8 0.0 3.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 KEG12326.1 - 0.11 12.6 0.2 0.22 11.6 0.1 1.5 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor LicD PF04991.13 KEG12327.1 - 2.5e-17 63.8 0.0 7.3e-15 55.7 0.0 2.1 1 1 1 2 2 2 2 LicD family Kinesin PF00225.23 KEG12328.1 - 1.7e-87 293.4 0.6 1.7e-87 293.4 0.6 3.6 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KEG12328.1 - 5.8e-17 62.0 0.0 1.5e-10 41.2 0.0 4.3 3 0 0 3 3 3 2 Microtubule binding Kinesin_assoc PF16183.5 KEG12328.1 - 1e-05 25.7 0.4 1e-05 25.7 0.4 4.7 1 1 3 4 4 4 1 Kinesin-associated MgsA_C PF12002.8 KEG12328.1 - 3.9 7.4 8.2 0.58 10.1 3.6 2.0 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal Utp11 PF03998.13 KEG12329.1 - 1.3e-35 123.5 32.8 7.2e-33 114.5 32.8 2.0 1 1 0 1 1 1 1 Utp11 protein PAS_10 PF13596.6 KEG12329.1 - 0.15 12.6 1.3 1.6 9.4 0.0 2.9 3 0 0 3 3 3 0 PAS domain RNA_pol_A_bac PF01000.26 KEG12330.1 - 1.6e-21 76.7 0.0 3e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEG12330.1 - 2.1e-11 43.1 0.0 3.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ETF_QO PF05187.13 KEG12330.1 - 0.029 14.5 0.3 0.057 13.6 0.3 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DUF2284 PF10050.9 KEG12330.1 - 0.066 13.0 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Fer4_10 PF13237.6 KEG12330.1 - 0.14 12.3 2.0 0.24 11.5 2.0 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEG12330.1 - 0.19 12.0 2.4 0.35 11.1 2.4 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KEG12330.1 - 0.26 11.9 2.1 0.53 10.9 2.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain HA2 PF04408.23 KEG12331.1 - 0.00012 22.3 0.0 0.00031 21.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_19 PF13245.6 KEG12331.1 - 0.00034 21.0 0.1 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ANF_receptor PF01094.28 KEG12332.1 - 9.9e-34 117.0 0.2 1.6e-18 67.0 0.1 3.0 2 2 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KEG12332.1 - 6.3e-06 26.1 0.0 0.018 14.7 0.0 3.7 3 1 0 3 3 3 2 Periplasmic binding protein MrpF_PhaF PF04066.13 KEG12332.1 - 8.3 6.9 7.0 1.1 9.7 1.4 2.5 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Histone PF00125.24 KEG12333.1 - 2.6e-36 124.9 1.0 3.2e-36 124.6 1.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEG12333.1 - 2.9e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KEG12333.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KEG12333.1 - 0.00018 21.6 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KEG12333.1 - 0.0044 17.4 0.0 0.0074 16.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein DUF1041 PF06292.17 KEG12333.1 - 0.005 17.2 0.0 0.0059 17.0 0.0 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1041) Bromo_TP PF07524.13 KEG12333.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CYTH PF01928.21 KEG12334.1 - 2.7e-12 47.0 2.4 2.8e-08 33.9 0.0 2.8 3 0 0 3 3 3 2 CYTH domain COG2 PF06148.11 KEG12334.1 - 0.095 12.8 0.5 2.3 8.3 0.0 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MHC2-interact PF09307.10 KEG12335.1 - 0.21 11.6 0.6 0.34 10.9 0.6 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting Aminotran_4 PF01063.19 KEG12336.1 - 2.5e-33 115.8 0.0 3.4e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Fer4_13 PF13370.6 KEG12336.1 - 0.039 14.5 0.2 0.089 13.3 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I EF-hand_7 PF13499.6 KEG12338.1 - 7.6e-23 80.7 7.4 3.5e-16 59.4 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG12338.1 - 8.4e-21 71.9 11.7 1.8e-07 30.2 1.8 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KEG12338.1 - 6.4e-19 66.2 5.1 3.5e-06 26.5 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KEG12338.1 - 2.2e-15 56.2 9.0 1.6e-12 47.0 1.0 3.3 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KEG12338.1 - 2.8e-13 50.0 0.8 2.1e-07 31.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KEG12338.1 - 4.3e-12 44.9 6.0 0.00044 19.6 1.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KEG12338.1 - 2.5e-05 24.1 0.7 0.074 13.0 0.2 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KEG12338.1 - 0.00047 20.1 0.1 0.27 11.2 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein EF-hand_14 PF17959.1 KEG12338.1 - 0.0038 17.5 3.6 0.21 11.9 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain MgtE_N PF03448.17 KEG12338.1 - 0.0074 16.9 2.3 0.02 15.5 0.8 2.2 2 0 0 2 2 2 1 MgtE intracellular N domain SurA_N_2 PF13623.6 KEG12338.1 - 0.032 14.1 3.4 0.86 9.5 0.6 2.5 1 1 1 2 2 2 0 SurA N-terminal domain DUF3164 PF11363.8 KEG12338.1 - 0.053 13.1 0.5 0.84 9.2 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3164) TerB PF05099.13 KEG12338.1 - 0.054 13.5 5.3 0.67 9.9 0.6 2.5 1 1 2 3 3 3 0 Tellurite resistance protein TerB HTH_40 PF14493.6 KEG12338.1 - 0.12 12.9 0.4 9 6.8 0.0 2.3 1 1 0 2 2 2 0 Helix-turn-helix domain SPARC_Ca_bdg PF10591.9 KEG12338.1 - 0.17 12.2 2.4 1.2 9.5 0.4 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3911 PF13050.6 KEG12338.1 - 0.86 9.8 4.8 2 8.6 0.5 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3911) CBFD_NFYB_HMF PF00808.23 KEG12340.1 - 2.3e-08 34.2 0.1 4.1e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEG12340.1 - 0.00019 21.8 0.4 0.00041 20.7 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PPP4R2 PF09184.11 KEG12340.1 - 0.77 9.3 5.8 1.2 8.7 5.8 1.3 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KEG12340.1 - 1.8 7.8 8.4 3.2 7.0 8.4 1.3 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 KEG12340.1 - 6.5 5.8 18.1 0.37 9.9 13.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2046 PF09755.9 KEG12341.1 - 0.0013 18.1 22.1 0.0013 18.1 22.1 2.7 2 2 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Borrelia_REV PF03978.13 KEG12341.1 - 0.023 14.7 0.7 0.068 13.1 0.2 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF3268 PF11672.8 KEG12341.1 - 0.023 15.0 0.0 0.053 13.8 0.0 1.6 1 1 0 1 1 1 0 zinc-finger-containing domain Rootletin PF15035.6 KEG12341.1 - 0.24 11.4 26.2 0.09 12.8 11.4 3.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 KEG12341.1 - 1.1 8.3 25.9 1.6 7.7 17.2 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sugar_tr PF00083.24 KEG12342.1 - 1.1e-80 271.7 22.8 1.4e-80 271.4 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEG12342.1 - 9.4e-16 57.7 22.9 9.4e-16 57.7 22.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Paramecium_SA PF01508.16 KEG12342.1 - 0.1 13.1 6.3 0.81 10.2 2.1 2.4 1 1 1 2 2 2 0 Paramecium surface antigen domain PSI PF01437.25 KEG12342.1 - 0.46 11.1 9.1 3.6 8.2 3.1 2.6 1 1 1 2 2 2 0 Plexin repeat tRNA-synt_2 PF00152.20 KEG12344.1 - 1.1e-85 287.5 0.0 1.8e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 KEG12344.1 - 9.4e-32 110.3 0.1 1.6e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 KEG12344.1 - 7.3e-10 38.7 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Clat_adaptor_s PF01217.20 KEG12345.1 - 8.1e-49 165.2 4.2 9e-49 165.1 4.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MMgT PF10270.9 KEG12346.1 - 0.23 11.9 2.0 0.62 10.4 2.0 1.7 1 1 0 1 1 1 0 Membrane magnesium transporter Metallothio_Pro PF02069.16 KEG12347.1 - 0.058 13.6 0.3 0.083 13.1 0.3 1.2 1 0 0 1 1 1 0 Prokaryotic metallothionein Cofilin_ADF PF00241.20 KEG12349.1 - 1.1e-19 70.5 0.0 1.2e-12 47.7 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TPR_12 PF13424.6 KEG12350.1 - 0.003 17.8 1.7 8.8 6.7 0.0 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12350.1 - 0.01 15.9 7.2 1.2 9.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12350.1 - 0.071 13.4 1.9 1.1 9.6 0.0 3.9 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG12350.1 - 0.089 13.5 2.2 66 4.5 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rhabdo_M2 PF04785.12 KEG12352.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Dak1 PF02733.17 KEG12353.1 - 1.5e-89 300.0 0.7 2.1e-89 299.5 0.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KEG12353.1 - 1e-41 142.7 3.4 1.9e-41 141.8 3.4 1.5 1 0 0 1 1 1 1 DAK2 domain PARP_regulatory PF01358.18 KEG12354.1 - 1.5e-15 56.9 0.0 1.5e-10 40.5 0.0 2.8 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit DUF2428 PF10350.9 KEG12357.1 - 2.8e-35 121.9 0.2 1.1e-34 120.0 0.0 2.1 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KEG12357.1 - 3.1 8.3 5.8 94 3.7 0.1 5.3 4 0 0 4 4 4 0 HEAT repeat TP_methylase PF00590.20 KEG12358.1 - 3.3e-18 66.4 2.4 3.5e-18 66.3 0.7 1.9 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases 6PGD PF00393.19 KEG12359.1 - 2.2e-75 253.7 0.0 3e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEG12359.1 - 8.9e-45 152.7 0.7 1.8e-44 151.7 0.7 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KEG12359.1 - 4.3e-05 23.6 0.2 0.00011 22.3 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KEG12359.1 - 6.1e-05 23.0 2.0 0.00013 21.9 0.2 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEG12359.1 - 0.0002 21.9 0.6 0.00042 20.8 0.6 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEG12359.1 - 0.0072 15.7 0.3 0.014 14.8 0.2 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KEG12359.1 - 0.0074 15.9 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 KEG12359.1 - 0.022 14.2 0.2 0.043 13.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEG12359.1 - 0.055 13.4 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_11 PF14833.6 KEG12359.1 - 0.06 13.6 0.4 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.22 KEG12359.1 - 0.096 13.5 0.1 0.25 12.2 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Mito_carr PF00153.27 KEG12360.1 - 1.2e-55 185.4 1.8 9e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR_1 PF13232.6 KEG12360.1 - 0.00011 22.8 0.0 0.00027 21.5 0.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like TRAPP PF04051.16 KEG12361.1 - 1.9e-22 79.6 0.0 2.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LRR_9 PF14580.6 KEG12364.1 - 2.9e-10 39.9 0.6 7.2e-10 38.6 0.6 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KEG12364.1 - 0.00032 20.4 3.0 0.0038 17.0 0.7 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KEG12364.1 - 0.00047 20.5 8.7 0.024 15.1 2.2 3.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG12364.1 - 0.17 12.1 0.7 4.9 7.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 KEG12365.1 - 6.2e-25 86.9 0.0 0.017 15.5 0.0 9.3 5 3 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG12365.1 - 5.2e-16 58.2 0.3 0.45 10.3 0.0 7.1 5 1 0 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 KEG12365.1 - 1.3e-13 49.8 5.6 0.023 14.7 0.1 10.8 13 0 0 13 13 13 3 Leucine Rich repeat LRR_9 PF14580.6 KEG12365.1 - 4.3e-05 23.1 3.2 8.2 5.9 0.0 5.0 2 1 3 5 5 5 3 Leucine-rich repeat DUF1375 PF07119.12 KEG12365.1 - 0.0042 17.4 1.7 34 4.9 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1375) TetR_C_2 PF08361.11 KEG12365.1 - 0.011 15.9 0.0 30 4.7 0.0 3.9 3 1 1 4 4 4 0 MAATS-type transcriptional repressor, C-terminal region LRR_4 PF12799.7 KEG12366.1 - 5.7e-23 80.6 0.0 0.00075 19.8 0.2 8.8 5 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG12366.1 - 3e-12 46.1 1.1 0.017 14.8 0.4 6.0 5 1 1 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 KEG12366.1 - 4.9e-06 26.2 5.9 8.4 6.7 0.0 9.3 10 0 0 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.33 KEG12366.1 - 0.0014 18.9 4.8 31 5.7 0.4 6.9 6 2 0 6 6 6 0 Leucine Rich Repeat COX5A PF02284.16 KEG12366.1 - 0.01 15.8 0.1 14 5.7 0.0 3.8 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va DUF1375 PF07119.12 KEG12366.1 - 0.037 14.4 0.3 15 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1375) HEAT PF02985.22 KEG12368.1 - 6.7e-05 22.8 9.8 11 6.6 0.3 8.4 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 KEG12368.1 - 0.011 14.4 1.1 0.029 12.9 0.2 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KEG12368.1 - 0.036 14.7 1.4 78 4.0 0.0 4.4 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KEG12368.1 - 0.045 13.8 9.3 2 8.4 0.2 4.9 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 IF-2B PF01008.17 KEG12369.1 - 1.4e-21 77.0 1.4 6.3e-19 68.3 1.4 3.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family PITH PF06201.13 KEG12370.1 - 1.1e-26 93.8 0.0 1.4e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.26 KEG12371.1 - 6.2e-43 146.5 0.8 7.9e-43 146.2 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.9 KEG12372.1 - 1.5e-20 73.6 0.0 1.7e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 KEG12372.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KEG12372.1 - 0.024 15.0 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEG12372.1 - 0.032 14.5 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEG12372.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KEG12372.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEG12372.1 - 0.12 12.8 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 KEG12372.1 - 0.21 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Metallophos PF00149.28 KEG12374.1 - 3.1e-07 31.1 0.0 5.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIIC_delta PF12657.7 KEG12374.1 - 0.093 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Ycf70 PF17382.2 KEG12375.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized Ycf70-like EMC3_TMCO1 PF01956.16 KEG12375.1 - 3.5 7.3 7.9 4.8 6.9 0.0 3.4 3 1 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like TPR_4 PF07721.14 KEG12377.1 - 0.032 14.8 0.8 0.37 11.6 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG12377.1 - 2.6 8.8 10.5 0.63 10.7 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 KEG12378.1 - 3.4e-07 30.1 0.0 4.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_M PF01068.21 KEG12379.1 - 9.7e-08 31.9 0.0 1.1e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KEG12380.1 - 2.3e-09 37.7 0.0 4.3e-09 36.9 0.0 1.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KEG12381.1 - 0.0025 18.2 0.0 0.031 14.7 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rhabdo_ncap PF00945.18 KEG12381.1 - 0.15 10.9 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Arf PF00025.21 KEG12385.1 - 6.3e-58 195.1 0.0 7.1e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG12385.1 - 4.1e-09 36.5 0.0 5.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KEG12385.1 - 9.1e-09 34.9 0.5 6.5e-06 25.5 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KEG12385.1 - 2.2e-08 33.7 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KEG12385.1 - 3.3e-08 33.3 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG12385.1 - 5.7e-08 33.0 0.0 1.1e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KEG12385.1 - 1.6e-06 27.8 0.2 0.001 18.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEG12385.1 - 0.00044 19.7 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KEG12385.1 - 0.00086 18.9 0.0 0.0068 16.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 KEG12385.1 - 0.0019 17.8 0.5 0.051 13.2 0.0 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KEG12385.1 - 0.044 13.4 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SNRNP27 PF08648.12 KEG12385.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins PduV-EutP PF10662.9 KEG12385.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Tubulin_C PF03953.17 KEG12388.1 - 0.094 12.9 0.3 0.31 11.2 0.3 1.9 1 0 0 1 1 1 0 Tubulin C-terminal domain Baculo_PEP_C PF04513.12 KEG12388.1 - 0.16 12.0 6.1 0.32 11.0 0.5 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40_alt PF14077.6 KEG12388.1 - 1.9 8.4 9.0 14 5.6 0.1 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif CCDC92 PF14916.6 KEG12388.1 - 2.8 7.8 14.5 0.28 11.0 3.8 3.3 3 0 0 3 3 3 0 Coiled-coil domain of unknown function MVP_shoulder PF11978.8 KEG12389.1 - 2.8e-49 166.1 0.1 6e-49 165.0 0.1 1.6 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 KEG12389.1 - 8e-49 163.5 3.9 1.7e-11 44.1 0.0 5.4 5 0 0 5 5 5 4 Major Vault Protein repeat domain Vault_3 PF17795.1 KEG12389.1 - 1e-31 108.8 2.2 4.6e-29 100.3 0.2 3.9 4 0 0 4 4 4 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 KEG12389.1 - 9.3e-31 106.0 3.0 1.7e-19 69.9 0.7 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 KEG12389.1 - 1.6e-20 72.9 0.0 9e-20 70.5 0.0 2.2 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 KEG12389.1 - 0.037 14.1 0.0 6.3 7.0 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3601) Lipocalin_2 PF08212.12 KEG12389.1 - 0.043 13.7 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipocalin-like domain Utp14 PF04615.13 KEG12390.1 - 0.04 12.5 5.0 0.039 12.5 5.0 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4642 PF15484.6 KEG12390.1 - 0.05 13.8 1.2 0.072 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF2457 PF10446.9 KEG12390.1 - 0.095 11.8 17.0 0.11 11.6 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KEG12390.1 - 0.17 11.5 5.2 0.25 11.0 5.2 1.4 1 0 0 1 1 1 0 FAM176 family PGA2 PF07543.12 KEG12390.1 - 0.18 11.8 4.7 0.29 11.1 4.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 GCIP PF13324.6 KEG12390.1 - 0.22 11.1 4.3 0.22 11.1 4.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 KEG12390.1 - 0.24 9.6 10.3 0.26 9.5 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KEG12390.1 - 0.3 10.5 9.4 0.34 10.3 9.4 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 KEG12390.1 - 0.61 8.6 11.5 0.67 8.5 11.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 KEG12390.1 - 1.9 7.7 7.8 2 7.7 7.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KEG12390.1 - 3 7.1 19.1 5 6.4 19.1 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KEG12390.1 - 6.4 4.7 16.1 6.8 4.7 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Dynein_light PF01221.18 KEG12391.1 - 4.4e-30 103.8 1.3 5.1e-30 103.6 1.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.6 KEG12391.1 - 0.0015 17.8 0.1 0.0015 17.8 0.1 1.2 1 0 0 1 1 1 1 Vasohibin Pkinase PF00069.25 KEG12392.1 - 4.6e-51 173.7 0.0 8.5e-51 172.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12392.1 - 1.3e-24 86.9 0.0 2.1e-20 73.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG12392.1 - 8.1e-05 22.7 0.5 0.00022 21.3 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG12392.1 - 0.00078 18.3 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEG12392.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEG12392.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEG12392.1 - 0.018 14.7 0.2 0.052 13.1 0.2 1.6 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KEG12392.1 - 0.044 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DEAD PF00270.29 KEG12393.1 - 2e-44 151.5 0.0 3.7e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG12393.1 - 2e-31 108.6 0.0 2.2e-28 98.8 0.0 3.3 2 1 1 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.12 KEG12393.1 - 2.3e-18 66.3 0.0 7.8e-18 64.6 0.0 2.0 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 KEG12393.1 - 2.1e-05 23.9 0.1 4.3e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEG12393.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Rrp15p PF07890.12 KEG12394.1 - 5.3e-11 43.0 15.7 1.5e-10 41.6 15.7 1.8 1 1 0 1 1 1 1 Rrp15p DUF3153 PF11353.8 KEG12394.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) LRR_6 PF13516.6 KEG12395.1 - 4.1e-29 98.1 20.0 0.00013 21.8 0.1 9.5 9 0 0 9 9 9 9 Leucine Rich repeat LRR_4 PF12799.7 KEG12395.1 - 1.2e-05 25.5 12.4 0.45 11.0 0.0 6.4 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG12395.1 - 0.002 18.4 5.2 36 5.5 0.0 6.3 7 1 0 7 7 7 1 Leucine Rich Repeat IGPD PF00475.18 KEG12395.1 - 0.031 14.6 0.2 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase Metallophos PF00149.28 KEG12397.1 - 1.4e-26 94.3 0.1 2.2e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.18 KEG12397.1 - 0.00018 22.0 0.0 0.0004 20.9 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Metallophos_2 PF12850.7 KEG12397.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Big_4 PF07532.11 KEG12399.1 - 0.033 13.9 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Macro PF01661.21 KEG12400.1 - 2.2e-05 24.4 0.0 3.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain DUF202 PF02656.15 KEG12400.1 - 0.066 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ECH_2 PF16113.5 KEG12401.1 - 1.6e-18 67.3 0.0 6.5e-11 42.3 0.0 4.0 3 1 1 4 4 4 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KEG12401.1 - 2.5e-07 30.3 0.0 2.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S8 PF00082.22 KEG12401.1 - 0.19 10.9 1.3 0.34 10.1 1.3 1.3 1 0 0 1 1 1 0 Subtilase family DUF3446 PF11928.8 KEG12401.1 - 0.51 10.7 5.5 1.3 9.4 5.5 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Pheromone PF08015.11 KEG12401.1 - 0.57 11.3 2.9 2.1 9.4 2.9 2.0 1 0 0 1 1 1 0 Fungal mating-type pheromone Ribosomal_L22e PF01776.17 KEG12402.1 - 1.4e-36 125.2 3.8 1.6e-36 125.0 3.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Asparaginase PF00710.20 KEG12403.1 - 3.8e-40 137.5 0.0 5.9e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KEG12403.1 - 3e-25 88.6 0.4 4.9e-25 88.0 0.4 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain NOB1_Zn_bind PF08772.11 KEG12404.1 - 0.011 15.9 4.2 0.016 15.3 0.3 2.8 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-B_box PF00643.24 KEG12404.1 - 0.089 13.0 6.6 0.09 12.9 0.4 2.6 3 0 0 3 3 3 0 B-box zinc finger Stanniocalcin PF03298.13 KEG12404.1 - 0.14 11.5 0.5 0.28 10.5 0.1 1.7 2 0 0 2 2 2 0 Stanniocalcin family Spc7 PF08317.11 KEG12404.1 - 2.1 7.1 9.1 0.3 9.9 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_19 PF14559.6 KEG12405.1 - 4e-07 30.5 0.1 0.0022 18.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG12405.1 - 2.2e-06 27.6 5.5 0.0031 17.8 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12405.1 - 0.00011 22.8 0.4 1.3 10.0 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12405.1 - 0.00014 21.7 0.9 0.00096 19.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG12405.1 - 0.00036 20.4 0.0 0.04 14.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG12405.1 - 0.00053 20.2 0.1 0.0061 16.8 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KEG12405.1 - 0.0017 18.1 0.4 0.041 13.7 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KEG12405.1 - 0.0027 18.0 0.1 0.083 13.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG12405.1 - 0.0093 16.2 0.3 0.038 14.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12405.1 - 0.014 15.0 1.4 0.39 10.4 0.1 3.5 3 1 1 4 4 4 0 TPR repeat Wzy_C_2 PF11846.8 KEG12405.1 - 0.024 14.5 0.2 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 KEG12405.1 - 0.027 14.3 0.1 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12405.1 - 0.058 13.6 0.1 0.058 13.6 0.1 2.4 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 KEG12405.1 - 0.067 13.1 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) DUF4116 PF13475.6 KEG12405.1 - 0.16 11.7 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Peptidase_M3 PF01432.20 KEG12406.1 - 3.1e-75 254.2 0.2 3.8e-74 250.6 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 KEG12406.1 - 0.00058 18.8 0.1 0.0016 17.3 0.1 1.7 2 0 0 2 2 2 1 Carboxypeptidase Taq (M32) metallopeptidase UCR_Fe-S_N PF10399.9 KEG12407.1 - 0.00043 19.6 6.1 0.00068 18.9 6.1 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CytB6-F_Fe-S PF08802.10 KEG12407.1 - 0.04 13.9 2.4 0.065 13.3 2.4 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DnaJ PF00226.31 KEG12408.1 - 1.3e-22 79.7 0.0 2.7e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Terminase_6C PF17289.2 KEG12408.1 - 0.022 14.8 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Terminase RNaseH-like domain E2F_TDP PF02319.20 KEG12408.1 - 0.1 12.7 0.8 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain Cas_APE2256 PF09651.10 KEG12408.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Aa_trans PF01490.18 KEG12409.1 - 2.2e-37 128.7 19.1 6.1e-33 114.1 8.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein MTS PF05175.14 KEG12410.1 - 1.9e-12 47.1 0.1 3.7e-10 39.6 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KEG12410.1 - 3.1e-11 43.3 0.0 7.5e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG12410.1 - 7.8e-09 36.1 0.1 4e-08 33.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KEG12410.1 - 6.1e-08 32.4 0.2 1.8e-07 30.9 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEG12410.1 - 3.6e-06 26.8 0.2 9.1e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_15 PF09445.10 KEG12410.1 - 8.3e-06 25.5 0.0 2e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 KEG12410.1 - 2.4e-05 25.0 0.0 5.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KEG12410.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 KEG12410.1 - 0.00048 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 KEG12410.1 - 0.00054 19.7 0.0 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KEG12410.1 - 0.00095 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 KEG12410.1 - 0.001 18.7 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KEG12410.1 - 0.0016 18.4 0.1 0.0034 17.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG12410.1 - 0.0022 18.6 0.2 0.0083 16.7 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG12410.1 - 0.0034 17.2 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KEG12410.1 - 0.0038 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa N6-adenineMlase PF10237.9 KEG12410.1 - 0.012 15.5 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Probable N6-adenine methyltransferase tRNA_U5-meth_tr PF05958.11 KEG12410.1 - 0.02 13.9 0.0 0.05 12.6 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase N6_Mtase PF02384.16 KEG12410.1 - 0.02 14.1 0.0 0.055 12.7 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_32 PF13679.6 KEG12410.1 - 0.021 14.8 0.2 0.049 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TRM PF02005.16 KEG12410.1 - 0.025 13.8 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Pox_MCEL PF03291.16 KEG12410.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Methyltr_RsmB-F PF01189.17 KEG12410.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF2870 PF11069.8 KEG12411.1 - 6.4e-38 129.0 0.1 1.4e-37 128.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Enterotoxin_b PF01376.18 KEG12411.1 - 0.098 12.9 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain DUF1077 PF06417.12 KEG12413.1 - 3.6e-37 127.0 0.8 4.2e-37 126.7 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF1772 PF08592.11 KEG12413.1 - 0.12 12.6 1.7 0.22 11.8 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) ELO PF01151.18 KEG12414.1 - 0.1 12.1 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 GNS1/SUR4 family stn_TNFRSF12A PF12191.8 KEG12416.1 - 0.012 15.8 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Actin PF00022.19 KEG12416.1 - 0.015 13.9 0.1 0.026 13.1 0.1 1.3 1 0 0 1 1 1 0 Actin SR-25 PF10500.9 KEG12416.1 - 4.4 6.8 15.4 8.2 6.0 15.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 KEG12416.1 - 9.7 4.5 7.6 9.1 4.6 5.3 1.8 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RRM_1 PF00076.22 KEG12418.1 - 6.5e-34 115.6 0.0 1.8e-10 40.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEG12418.1 - 0.0051 16.8 0.2 0.71 9.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEG12418.1 - 0.037 14.1 0.2 1.5 9.0 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif DREV PF05219.12 KEG12419.1 - 3.9e-59 199.9 0.0 4.6e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KEG12419.1 - 6.5e-08 32.6 0.0 9.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG12419.1 - 4.6e-07 30.5 0.0 3.4e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG12419.1 - 0.00022 21.8 0.0 0.00058 20.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG12419.1 - 0.0021 18.7 0.0 0.0053 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AAA_lid_2 PF17863.1 KEG12419.1 - 0.0098 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain Methyltransf_31 PF13847.6 KEG12419.1 - 0.022 14.5 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 KEG12419.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KEG12419.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain IQ PF00612.27 KEG12421.1 - 4.3e-05 23.0 19.9 0.005 16.5 1.0 5.6 5 0 0 5 5 5 4 IQ calmodulin-binding motif Spt20 PF12090.8 KEG12421.1 - 5.7 6.5 10.3 11 5.5 10.3 1.4 1 0 0 1 1 1 0 Spt20 family Sdh5 PF03937.16 KEG12422.1 - 7.3e-23 80.3 0.1 1.1e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase RF-1 PF00472.20 KEG12423.1 - 7.4e-12 45.2 0.1 1.1e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KEG12423.1 - 0.026 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein TAT_signal PF10518.9 KEG12424.1 - 0.77 9.7 3.3 1.4 8.9 3.3 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence SUR7 PF06687.12 KEG12425.1 - 0.069 12.8 12.5 0.088 12.4 4.1 2.8 2 0 0 2 2 2 0 SUR7/PalI family DUF2207 PF09972.9 KEG12425.1 - 0.18 10.5 9.0 0.12 11.1 0.8 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) CH_2 PF06294.11 KEG12426.1 - 5.5e-24 84.1 0.0 1.3e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KEG12426.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Peptidase_M24 PF00557.24 KEG12427.1 - 2.1e-47 161.5 0.1 2.6e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KEG12427.1 - 1e-13 51.3 9.5 2.1e-13 50.3 9.5 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KEG12427.1 - 6.5e-05 22.9 4.7 0.00014 21.8 4.7 1.6 1 0 0 1 1 1 1 MYND finger DHBP_synthase PF00926.19 KEG12427.1 - 0.1 12.1 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-UBR PF02207.20 KEG12427.1 - 3.2 8.0 8.6 4.9 7.4 3.0 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) LRR_4 PF12799.7 KEG12428.1 - 0.00011 22.5 6.0 0.043 14.3 0.0 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG12428.1 - 0.022 14.3 0.5 0.073 12.6 0.4 1.7 1 1 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 KEG12428.1 - 0.024 14.4 0.8 2.2 8.1 0.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat IQ PF00612.27 KEG12429.1 - 5.2 7.1 32.2 1 9.3 2.1 5.7 5 0 0 5 5 5 0 IQ calmodulin-binding motif Arginase PF00491.21 KEG12430.1 - 1.6e-49 168.9 0.0 1.9e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF4859 PF16151.5 KEG12432.1 - 0.34 10.8 1.7 0.53 10.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) ZapB PF06005.12 KEG12433.1 - 0.028 14.9 5.8 0.099 13.1 1.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 KEG12433.1 - 0.048 13.8 0.6 0.048 13.8 0.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF4140 PF13600.6 KEG12433.1 - 0.083 13.3 0.9 4 8.0 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cons_hypoth698 PF03601.14 KEG12434.1 - 0.054 12.4 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 Rap1-DNA-bind PF09197.10 KEG12435.1 - 0.0038 17.8 0.0 0.0096 16.5 0.0 1.6 1 0 0 1 1 1 1 Rap1, DNA-binding CCDC53 PF10152.9 KEG12436.1 - 1.9e-13 51.1 0.0 2.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Adaptin_N PF01602.20 KEG12437.1 - 1.7e-73 248.0 14.1 2.2e-73 247.6 14.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KEG12437.1 - 3e-31 108.6 0.1 7.2e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KEG12437.1 - 3.1e-24 85.3 0.0 6.7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KEG12437.1 - 3.1e-07 30.7 1.2 0.00032 21.0 0.0 3.9 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KEG12437.1 - 0.00061 19.9 12.4 0.00081 19.5 1.2 4.1 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEG12437.1 - 0.0021 18.2 3.6 7 7.2 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat IQ PF00612.27 KEG12438.1 - 6.8e-22 75.2 105.8 0.0052 16.5 4.6 17.7 15 1 2 17 17 17 15 IQ calmodulin-binding motif ADP_ribosyl_GH PF03747.14 KEG12441.1 - 1.5e-10 41.3 0.4 3.9e-06 26.8 0.1 2.5 1 1 0 2 2 2 2 ADP-ribosylglycohydrolase LRR_4 PF12799.7 KEG12442.1 - 4.3e-13 49.2 6.4 0.00039 20.7 0.3 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) IQ PF00612.27 KEG12442.1 - 9.6e-13 46.7 11.9 9.9e-05 21.8 0.8 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif LRR_8 PF13855.6 KEG12442.1 - 1.9e-10 40.3 9.2 0.00016 21.4 0.0 4.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KEG12442.1 - 2.7e-07 30.3 0.1 6.7e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KEG12442.1 - 0.009 16.0 8.4 25 5.3 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat SVIP PF15811.5 KEG12442.1 - 0.072 13.5 1.3 0.19 12.2 1.3 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein DUF1515 PF07439.11 KEG12442.1 - 0.077 13.0 0.2 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) LRR_1 PF00560.33 KEG12442.1 - 0.4 11.4 8.7 1.7e+02 3.4 0.2 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat Tricorn_C1 PF14684.6 KEG12442.1 - 3.1 7.9 4.4 2.8 8.1 0.1 3.1 4 0 0 4 4 4 0 Tricorn protease C1 domain HEAT_2 PF13646.6 KEG12443.1 - 2.2e-07 31.2 18.5 0.1 13.0 0.1 7.0 3 2 5 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 KEG12443.1 - 2.3e-07 31.2 5.2 0.45 11.1 0.0 7.3 6 2 3 9 9 9 2 HEAT-like repeat SF3b1 PF08920.10 KEG12443.1 - 1.6e-06 28.6 12.8 0.00026 21.5 12.8 2.9 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.22 KEG12443.1 - 6.7e-06 25.9 9.6 0.85 10.0 0.2 8.5 9 0 0 9 9 9 2 HEAT repeat CTD PF12815.7 KEG12443.1 - 0.00019 21.9 21.0 0.0013 19.3 11.9 3.2 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Arm PF00514.23 KEG12443.1 - 0.024 14.7 0.4 27 5.0 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KEG12443.1 - 0.05 13.5 2.3 5.1 7.0 0.1 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Chromo_shadow PF01393.19 KEG12444.1 - 0.017 15.2 0.0 0.054 13.6 0.0 1.9 2 0 0 2 2 2 0 Chromo shadow domain Ribosomal_S17e PF00833.18 KEG12445.1 - 8.7e-52 174.2 3.1 1.1e-51 173.9 3.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 HEAT_2 PF13646.6 KEG12446.1 - 7.2e-12 45.5 23.3 0.00033 21.0 0.2 5.7 5 2 1 6 6 6 4 HEAT repeats CYYR1 PF10873.8 KEG12446.1 - 0.00036 21.0 0.3 0.0019 18.7 0.0 2.2 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 HEAT PF02985.22 KEG12446.1 - 0.0048 17.1 0.0 0.0048 17.1 0.0 6.9 9 0 0 9 9 9 3 HEAT repeat PIF1 PF05970.14 KEG12447.1 - 1.3e-30 106.8 0.2 1.5e-26 93.5 0.0 3.0 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KEG12447.1 - 7.6e-18 64.9 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG12447.1 - 4.2e-07 30.4 0.1 1.3e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KEG12447.1 - 0.00038 20.2 0.0 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KEG12447.1 - 0.00054 19.8 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KEG12447.1 - 0.0068 16.8 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KEG12447.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 KEG12447.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KEG12447.1 - 0.029 14.6 1.0 0.27 11.5 1.0 2.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEG12447.1 - 0.032 14.7 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KEG12447.1 - 0.064 12.5 0.8 0.19 10.9 0.8 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KEG12447.1 - 0.094 12.1 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KEG12447.1 - 0.098 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF853 PF05872.12 KEG12447.1 - 0.1 11.2 0.3 0.2 10.2 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 KEG12447.1 - 0.1 12.4 0.2 1 9.1 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 KEG12447.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KEG12447.1 - 0.12 12.3 2.6 0.5 10.3 0.3 2.4 1 1 1 2 2 2 0 NTPase MobB PF03205.14 KEG12447.1 - 0.21 11.5 0.3 0.45 10.4 0.3 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Herpes_Helicase PF02689.14 KEG12447.1 - 0.22 9.4 0.1 8.6 4.1 0.0 2.1 2 0 0 2 2 2 0 Helicase CbiA PF01656.23 KEG12447.1 - 0.23 11.5 0.9 0.61 10.1 0.9 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain R3H PF01424.22 KEG12448.1 - 1.5e-08 34.5 0.0 4.2e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain Pex14_N PF04695.13 KEG12448.1 - 1.2 9.7 5.6 7.3 7.2 0.2 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5423 PF17461.2 KEG12449.1 - 0.0076 15.1 0.1 0.0091 14.9 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5423) DUF975 PF06161.11 KEG12449.1 - 0.05 13.4 0.2 0.063 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Methyltr_RsmB-F PF01189.17 KEG12450.1 - 0.00074 19.2 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Robl_LC7 PF03259.17 KEG12451.1 - 6.1e-10 38.7 0.2 7.6e-10 38.4 0.2 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Toxin_36 PF10550.9 KEG12451.1 - 0.11 13.9 0.2 0.41 12.1 0.2 2.0 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin zf-CCCH PF00642.24 KEG12452.1 - 8.3e-07 28.8 8.7 0.0003 20.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG12452.1 - 0.00084 20.0 7.7 0.02 15.6 0.0 2.9 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KEG12452.1 - 0.0064 16.3 9.0 0.039 13.7 2.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG12452.1 - 0.013 15.6 11.8 0.022 14.8 3.4 2.6 2 0 0 2 2 2 0 Zinc finger domain TFIIA PF03153.13 KEG12452.1 - 0.065 13.2 17.8 0.12 12.4 17.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH_2 PF14608.6 KEG12452.1 - 1.7 9.3 5.9 0.97 10.0 1.7 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Nuc_sug_transp PF04142.15 KEG12453.1 - 4e-65 220.1 23.7 3.1e-59 200.7 15.8 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.6 KEG12453.1 - 0.00039 20.1 5.6 0.00039 20.1 5.6 2.3 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter EamA PF00892.20 KEG12453.1 - 0.00097 19.3 6.2 0.00097 19.3 6.2 3.3 3 1 0 3 3 3 1 EamA-like transporter family FA_desaturase PF00487.24 KEG12453.1 - 0.011 15.6 1.2 0.011 15.6 1.2 2.4 3 0 0 3 3 3 0 Fatty acid desaturase DEAD PF00270.29 KEG12454.1 - 5.5e-14 52.3 0.0 1.3e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG12454.1 - 8e-06 26.2 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG12454.1 - 4.8e-05 23.4 0.0 0.00016 21.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KEG12454.1 - 0.0046 16.6 0.4 0.019 14.5 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEG12454.1 - 0.0064 16.2 0.0 0.035 13.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KEG12454.1 - 0.012 15.3 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KEG12454.1 - 0.032 14.5 0.0 0.52 10.6 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEG12454.1 - 0.038 14.3 1.1 0.15 12.4 0.0 2.5 3 1 0 3 3 3 0 AAA domain SecA_DEAD PF07517.14 KEG12454.1 - 0.17 11.1 0.0 7.5 5.7 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain TPR_17 PF13431.6 KEG12455.1 - 2.6e-09 36.8 0.2 1 9.9 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12455.1 - 0.0001 21.9 0.0 0.069 12.9 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 KEG12455.1 - 0.0047 17.5 6.1 7.4 7.3 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG12455.1 - 0.0074 16.9 1.8 4.1 8.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG12455.1 - 0.014 15.9 3.2 5.4 7.6 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 KEG12455.1 - 0.024 13.9 0.1 0.058 12.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12455.1 - 0.042 14.0 0.1 29 5.1 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12455.1 - 0.043 14.6 12.9 8 7.6 0.1 6.4 4 2 2 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG12455.1 - 0.1 12.9 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RRM_1 PF00076.22 KEG12456.1 - 1.1e-12 47.5 0.0 1.4e-10 40.8 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_PH PF01138.21 KEG12457.1 - 6.2e-07 30.0 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEG12457.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 zf-C2HC_2 PF13913.6 KEG12458.1 - 3.6e-23 80.9 13.9 6.8e-10 38.6 0.5 3.4 3 0 0 3 3 3 3 zinc-finger of a C2HC-type DZR PF12773.7 KEG12458.1 - 9.9e-05 22.3 9.9 0.00072 19.5 0.6 4.3 4 0 0 4 4 4 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KEG12458.1 - 0.0004 20.0 3.7 0.0004 20.0 3.7 3.6 4 0 0 4 4 4 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KEG12458.1 - 0.0056 16.1 0.5 0.0056 16.1 0.5 3.3 3 0 0 3 3 3 1 zinc-ribbon domain Sgf11 PF08209.11 KEG12458.1 - 0.017 14.7 5.9 2 8.1 0.2 2.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_15 PF17032.5 KEG12458.1 - 0.046 14.5 6.3 0.77 10.5 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon family DUF4187 PF13821.6 KEG12458.1 - 0.068 13.0 1.3 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) DUF2318 PF10080.9 KEG12458.1 - 0.09 12.9 6.1 3.6 7.8 0.1 3.9 4 0 0 4 4 4 0 Predicted membrane protein (DUF2318) ADK_lid PF05191.14 KEG12458.1 - 0.19 11.7 10.8 0.3 11.1 0.3 4.0 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2 PF00096.26 KEG12458.1 - 0.25 11.9 12.2 0.7 10.5 0.1 4.2 4 0 0 4 4 3 0 Zinc finger, C2H2 type HypA PF01155.19 KEG12458.1 - 0.33 11.0 7.6 13 5.8 0.4 3.8 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 KEG12458.1 - 1.7 8.4 5.9 0.63 9.8 0.1 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.6 KEG12458.1 - 1.9 8.4 6.5 17 5.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain XAF1_C PF18608.1 KEG12458.1 - 2.1 7.9 10.1 2.7 7.6 0.3 3.3 4 0 0 4 4 4 0 XIAP-associated factor 1 C-terminal domain zf-C2H2_4 PF13894.6 KEG12458.1 - 2.2 9.3 18.1 1.1 10.3 1.3 4.0 4 0 0 4 4 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KEG12458.1 - 2.6 7.7 9.1 15 5.3 0.1 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-RING_7 PF02591.15 KEG12458.1 - 3.8 7.8 10.9 4.2 7.6 0.2 3.5 3 1 1 4 4 3 0 C4-type zinc ribbon domain XPA_N PF01286.18 KEG12458.1 - 4.1 7.5 7.8 59 3.8 0.0 4.0 4 0 0 4 4 4 0 XPA protein N-terminal DUF35_N PF12172.8 KEG12458.1 - 4.7 7.2 0.0 4.7 7.2 0.0 3.4 3 1 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PLATZ PF04640.14 KEG12458.1 - 8.1 7.2 10.0 4.3 8.0 0.1 4.1 4 0 0 4 4 3 0 PLATZ transcription factor S36_mt PF10937.8 KEG12459.1 - 4e-05 25.2 0.1 7.5e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Vta1_C PF18097.1 KEG12462.1 - 0.34 10.7 1.4 3.2 7.5 0.3 2.8 2 0 0 2 2 2 0 Vta1 C-terminal domain Sedlin_N PF04628.13 KEG12463.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4531 PF15041.6 KEG12463.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) DUF4460 PF14687.6 KEG12464.1 - 1.8e-09 37.6 0.2 5.7e-09 36.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 KEG12464.1 - 2e-06 27.8 1.0 0.035 13.9 1.4 3.0 1 1 0 2 2 2 2 Domain of unknown function (DUF4461) LRR_4 PF12799.7 KEG12465.1 - 0.016 15.6 1.1 6.7 7.3 0.1 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG12465.1 - 2 8.7 10.5 2.3 8.5 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat DUF4012 PF13196.6 KEG12466.1 - 0.14 12.6 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) ELMO_CED12 PF04727.13 KEG12467.1 - 1.1e-43 149.5 0.2 1.8e-43 148.7 0.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_C12 PF01088.21 KEG12470.1 - 1.4e-52 178.5 0.0 2e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KEG12470.1 - 6.8e-16 57.9 2.3 1.4e-15 56.9 2.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases NBP1 PF08537.10 KEG12470.1 - 0.035 13.5 0.6 0.069 12.5 0.3 1.5 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 RRM_occluded PF16842.5 KEG12471.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif ThiF PF00899.21 KEG12473.1 - 2.9e-32 112.0 0.2 3.8e-32 111.6 0.2 1.2 1 0 0 1 1 1 1 ThiF family ERbeta_N PF12497.8 KEG12474.1 - 0.33 10.7 2.8 0.2 11.5 0.3 1.9 2 0 0 2 2 2 0 Estrogen receptor beta DUF3456 PF11938.8 KEG12475.1 - 5.4e-06 27.0 3.4 0.00014 22.4 3.4 2.2 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP EGF_Tenascin PF18720.1 KEG12475.1 - 0.16 12.1 0.9 6.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Tenascin EGF domain LRR_9 PF14580.6 KEG12476.1 - 7.8e-44 149.2 16.4 6.2e-11 42.1 0.0 8.6 4 3 4 8 8 8 8 Leucine-rich repeat LRR_4 PF12799.7 KEG12476.1 - 9.1e-37 124.5 69.6 3.5e-05 24.1 0.2 14.2 7 3 10 18 18 18 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG12476.1 - 7.2e-32 109.0 70.5 1.5e-08 34.3 7.6 12.4 10 3 5 15 15 15 10 Leucine rich repeat LRR_5 PF13306.6 KEG12476.1 - 0.018 15.0 0.1 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KEG12476.1 - 9.1 6.6 39.7 1.9 8.7 0.2 10.5 12 0 0 12 12 12 0 Leucine Rich repeat MPP6 PF10175.9 KEG12477.1 - 0.43 11.1 9.5 2.8 8.4 9.5 2.2 1 1 0 1 1 1 0 M-phase phosphoprotein 6 DAZAP2 PF11029.8 KEG12478.1 - 0.1 13.5 0.1 0.1 13.5 0.1 2.8 3 0 0 3 3 3 0 DAZ associated protein 2 (DAZAP2) FliD_C PF07195.12 KEG12478.1 - 0.77 9.1 9.6 3.1 7.2 3.9 3.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus RapH_N PF18801.1 KEG12478.1 - 1.2 9.2 10.6 3.4 7.8 0.3 4.0 4 0 0 4 4 4 0 response regulator aspartate phosphatase H, N terminal DnaJ PF00226.31 KEG12479.1 - 7.6e-17 61.2 1.9 1.4e-16 60.4 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 KEG12479.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin ENT PF03735.14 KEG12480.1 - 7.8e-07 29.1 0.1 7.8e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 ENT domain T2SSK PF03934.13 KEG12480.1 - 0.059 12.7 0.1 0.059 12.7 0.1 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K TRM13 PF05206.14 KEG12481.1 - 1.5e-14 54.1 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.6 KEG12481.1 - 2.3e-09 37.4 1.0 7.6e-08 32.5 2.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEG12481.1 - 0.19 11.3 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KEG12481.1 - 0.23 10.8 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Glycos_transf_2 PF00535.26 KEG12482.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEG12482.1 - 0.004 17.1 0.1 0.0066 16.4 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KEG12483.1 - 2.1e-185 617.8 0.0 2.9e-185 617.4 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 KEG12483.1 - 0.065 13.6 0.0 0.065 13.6 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 KEG12483.1 - 0.072 12.6 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Microtub_bd PF16796.5 KEG12483.1 - 0.16 11.9 1.0 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding AAA_22 PF13401.6 KEG12483.1 - 0.47 10.7 1.9 1 9.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain DAO PF01266.24 KEG12484.1 - 1e-45 156.9 0.0 1.7e-45 156.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEG12484.1 - 1.1e-29 102.8 0.0 1.9e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 KEG12484.1 - 2.9e-05 23.6 0.3 4.7e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEG12484.1 - 0.0025 17.1 2.4 0.023 13.9 2.4 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KEG12484.1 - 0.0071 15.5 3.8 0.01 14.9 1.5 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEG12484.1 - 0.0088 15.3 0.0 0.026 13.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG12484.1 - 0.02 14.2 0.1 1.9 7.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEG12484.1 - 0.036 13.1 2.7 0.25 10.4 0.5 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KEG12484.1 - 0.078 13.2 1.4 0.21 11.8 0.9 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KEG12484.1 - 0.097 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KEG12484.1 - 0.31 11.6 2.2 0.93 10.1 0.5 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase NADH-u_ox-rdase PF10785.9 KEG12485.1 - 6.8e-14 52.3 2.5 6.8e-14 52.3 2.5 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF2499 PF10693.9 KEG12485.1 - 0.41 11.0 2.5 3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) SBF_like PF13593.6 KEG12487.1 - 2.3e-59 201.3 15.8 2.7e-59 201.0 15.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KEG12487.1 - 5.2e-05 23.0 2.8 5.2e-05 23.0 2.8 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4064 PF13273.6 KEG12487.1 - 0.043 14.1 1.4 0.14 12.4 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_M8 PF01457.16 KEG12488.1 - 3.8e-84 283.3 0.2 5.2e-84 282.8 0.2 1.1 1 0 0 1 1 1 1 Leishmanolysin KDZ PF18758.1 KEG12488.1 - 0.043 13.4 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Hydrophobin_2 PF06766.11 KEG12488.1 - 0.099 12.6 2.0 0.2 11.7 0.5 2.3 2 0 0 2 2 2 0 Fungal hydrophobin PAPS_reduct PF01507.19 KEG12489.1 - 5.8e-21 75.3 0.1 5.1e-18 65.7 0.0 2.4 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Skp1_POZ PF03931.15 KEG12490.1 - 0.029 14.5 0.0 1.1 9.5 0.0 2.1 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain DUF3439 PF11921.8 KEG12491.1 - 0.0062 16.5 3.2 0.0087 16.0 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Skp1_POZ PF03931.15 KEG12491.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 1 1 2 2 2 0 Skp1 family, tetramerisation domain zf-HIT PF04438.16 KEG12492.1 - 2.9e-07 30.2 10.4 8.7e-07 28.7 10.4 1.8 1 0 0 1 1 1 1 HIT zinc finger zf-CCCH PF00642.24 KEG12492.1 - 0.0038 17.1 1.4 0.0038 17.1 1.4 2.6 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KEG12492.1 - 0.0043 17.2 0.6 0.0043 17.2 0.6 2.6 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEG12492.1 - 0.051 14.1 2.0 0.051 14.1 2.0 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger HEAT PF02985.22 KEG12493.1 - 4.8e-05 23.3 8.3 1.1 9.7 0.1 5.3 6 0 0 6 6 6 2 HEAT repeat TIP120 PF08623.10 KEG12493.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KEG12493.1 - 0.0054 17.1 3.0 0.058 13.8 0.9 3.1 2 1 2 4 4 4 3 HEAT repeats RIB43A PF05914.12 KEG12493.1 - 0.012 14.3 3.0 0.086 11.6 0.2 2.1 2 0 0 2 2 2 0 RIB43A Cnd1 PF12717.7 KEG12493.1 - 0.08 13.0 0.1 0.39 10.8 0.0 2.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 OsmC PF02566.19 KEG12497.1 - 8.8e-05 22.9 0.0 0.00017 22.0 0.0 1.4 1 1 0 1 1 1 1 OsmC-like protein ATP-synt_F PF01990.17 KEG12499.1 - 6.6e-31 106.5 0.1 8.1e-31 106.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF3764 PF12594.8 KEG12499.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) PGI PF00342.19 KEG12500.1 - 6.6e-250 829.7 1.0 7.6e-250 829.5 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Nab6_mRNP_bdg PF10567.9 KEG12500.1 - 0.2 11.1 1.9 18 4.7 0.0 2.6 2 1 0 2 2 2 0 RNA-recognition motif TPR_19 PF14559.6 KEG12504.1 - 3.8e-09 36.9 2.4 0.24 11.9 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12504.1 - 1e-07 31.5 18.5 0.073 13.2 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12504.1 - 0.0019 17.8 0.2 0.13 11.9 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 KEG12504.1 - 0.0095 15.7 8.5 12 5.9 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12504.1 - 0.015 15.5 6.0 47 4.6 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Mso1_Sec1_bdg PF14475.6 KEG12504.1 - 0.065 12.8 0.1 5.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Sec1-binding region of Mso1 TPR_17 PF13431.6 KEG12504.1 - 0.097 13.1 0.0 37 5.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG12504.1 - 2 8.6 13.7 2.5 8.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat FUSC_2 PF13515.6 KEG12505.1 - 1.6e-17 63.8 28.2 2e-16 60.2 11.5 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like Spt20 PF12090.8 KEG12505.1 - 2.8 7.5 8.4 3.2 7.3 6.8 1.8 2 0 0 2 2 2 0 Spt20 family Sulfatase PF00884.23 KEG12506.1 - 2.1e-06 27.4 0.0 4.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEG12506.1 - 0.002 17.8 0.0 0.46 10.0 0.0 2.7 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_8 PF13181.6 KEG12507.1 - 3e-13 48.9 14.1 2.9e-05 23.9 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12507.1 - 3e-13 48.8 24.5 0.0048 16.9 0.2 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG12507.1 - 1.3e-11 43.8 11.1 0.00044 19.9 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12507.1 - 1.6e-08 34.0 4.7 5.4e-05 22.8 0.5 3.7 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 KEG12507.1 - 1.9e-07 31.5 4.3 0.0018 18.8 0.1 5.4 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG12507.1 - 4.1e-07 29.9 4.2 0.17 12.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12507.1 - 1.5e-05 25.4 22.9 0.0065 17.2 0.8 7.5 7 2 1 8 8 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG12507.1 - 4e-05 23.7 10.5 0.53 10.5 0.1 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KEG12507.1 - 9.9e-05 22.9 0.8 9.9e-05 22.9 0.8 7.6 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEG12507.1 - 0.0001 21.6 1.1 0.0004 19.7 1.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC8 PF04049.13 KEG12507.1 - 0.00013 22.1 0.0 0.0017 18.4 0.0 2.4 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 SAP130_C PF16014.5 KEG12507.1 - 0.019 14.1 1.2 0.04 13.0 1.2 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus TPR_7 PF13176.6 KEG12507.1 - 0.022 14.7 13.4 13 6.1 0.5 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 KEG12507.1 - 0.11 12.9 7.9 5 7.6 0.2 3.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KEG12507.1 - 0.22 11.7 6.9 0.36 11.0 0.4 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG12507.1 - 3.5 8.5 16.7 7.4 7.4 0.1 6.7 8 1 0 8 8 6 0 Tetratricopeptide repeat DUF4678 PF15727.5 KEG12508.1 - 0.079 12.2 7.6 0.12 11.6 7.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4678) S4_2 PF13275.6 KEG12508.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 S4 domain DUF3450 PF11932.8 KEG12508.1 - 0.28 10.4 24.0 3 7.1 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KEG12508.1 - 0.5 10.6 27.7 0.027 14.7 11.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 KEG12508.1 - 0.56 10.5 7.0 1.2 9.4 0.1 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper APG6_N PF17675.1 KEG12508.1 - 0.57 10.7 27.2 0.86 10.1 11.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 KEG12508.1 - 0.88 8.9 17.9 0.85 8.9 6.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Csm2_III-A PF03750.13 KEG12508.1 - 2.4 9.0 6.4 6.6 7.6 6.1 1.8 1 1 0 1 1 1 0 Csm2 Type III-A V_ATPase_I PF01496.19 KEG12508.1 - 6.9 4.5 11.3 7.8 4.3 11.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.12 KEG12508.1 - 7.8 6.6 28.6 3.1 7.9 17.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GSHPx PF00255.19 KEG12509.1 - 1.2e-37 127.8 0.2 1.5e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 KEG12509.1 - 2.7e-05 23.9 0.0 7.2e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEG12509.1 - 0.00012 21.9 0.1 0.00027 20.8 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family GSHPx PF00255.19 KEG12510.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 KEG12511.1 - 1.5e-38 130.6 0.4 1.9e-38 130.3 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KEG12511.1 - 6.7e-06 26.0 0.1 1.6e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEG12511.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.6 1 1 0 1 1 1 1 Redoxin Myosin_TH1 PF06017.13 KEG12512.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding AsnA PF03590.15 KEG12513.1 - 3.8e-93 311.4 0.0 4.6e-93 311.1 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 KEG12513.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WW PF00397.26 KEG12515.1 - 1e-06 28.7 3.3 2.4e-06 27.5 3.3 1.6 1 0 0 1 1 1 1 WW domain DUF4745 PF15923.5 KEG12515.1 - 0.048 13.6 0.7 0.091 12.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) NDUF_B5 PF09781.9 KEG12515.1 - 0.09 12.4 1.6 0.29 10.7 1.6 1.8 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit HALZ PF02183.18 KEG12515.1 - 1.7 8.9 5.3 23 5.3 0.2 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper IF3_N PF05198.16 KEG12517.1 - 0.00095 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain BtrH_N PF14399.6 KEG12517.1 - 0.098 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal XRN_N PF03159.18 KEG12518.1 - 6.8e-06 25.7 0.0 0.00029 20.3 0.0 2.2 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus Exo_endo_phos PF03372.23 KEG12518.1 - 4.8e-05 23.0 0.0 0.00017 21.2 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FYRC PF05965.14 KEG12519.1 - 3.3e-05 24.0 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KEG12519.1 - 0.045 13.6 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 F/Y-rich N-terminus Ribosomal_S9 PF00380.19 KEG12520.1 - 3.3e-26 92.2 2.3 3.9e-26 91.9 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Kinesin PF00225.23 KEG12521.1 - 4.5e-33 114.6 0.0 5e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG12521.1 - 3.2e-25 88.8 0.0 9e-25 87.3 0.0 1.6 1 1 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 KEG12521.1 - 0.071 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Kinesin PF00225.23 KEG12522.1 - 8.4e-94 314.2 0.0 9.9e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG12522.1 - 1e-27 96.9 0.0 3.2e-27 95.3 0.0 1.8 1 1 0 1 1 1 1 Microtubule binding Helicase_C PF00271.31 KEG12524.1 - 7e-07 29.6 0.0 6.9e-06 26.4 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG12524.1 - 2.1e-05 24.4 0.0 5.4e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DAP3 PF10236.9 KEG12524.1 - 0.068 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 KEG12524.1 - 0.12 12.4 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UQ_con PF00179.26 KEG12525.1 - 2.5e-19 69.3 0.0 3.2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEG12525.1 - 0.0044 17.3 0.0 0.0064 16.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain BRE PF06113.12 KEG12525.1 - 0.045 12.6 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) HMGL-like PF00682.19 KEG12526.1 - 3.5e-26 92.3 0.0 6.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like EF-hand_7 PF13499.6 KEG12526.1 - 4.5e-07 30.2 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG12526.1 - 0.00013 21.3 0.0 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KEG12526.1 - 0.00072 19.3 0.0 0.0042 16.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Zeta_toxin PF06414.12 KEG12527.1 - 2.9e-14 52.8 0.0 2.8e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 KEG12527.1 - 0.00031 20.9 0.0 0.0006 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEG12527.1 - 0.00097 18.7 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KEG12527.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C15 PF01470.17 KEG12528.1 - 7.2e-07 29.6 0.1 0.0022 18.2 0.0 2.6 2 1 0 2 2 2 2 Pyroglutamyl peptidase CR6_interact PF10147.9 KEG12529.1 - 0.12 12.0 0.2 0.4 10.4 0.2 1.8 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ArfGap PF01412.18 KEG12530.1 - 0.04 14.0 0.3 0.057 13.5 0.3 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf S-AdoMet_synt_N PF00438.20 KEG12530.1 - 0.087 13.5 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain RCC1 PF00415.18 KEG12531.1 - 4.1e-30 104.2 1.1 5.3e-11 43.0 0.1 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG12531.1 - 3.2e-18 65.0 10.9 1.5e-08 34.2 0.6 4.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat TPR_10 PF13374.6 KEG12532.1 - 6.9e-09 35.3 1.2 0.0023 17.8 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG12532.1 - 3.4e-07 30.5 2.0 5.1e-05 23.5 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat IQ PF00612.27 KEG12532.1 - 1.1e-06 28.0 49.3 0.049 13.4 1.8 8.1 8 0 0 8 8 8 6 IQ calmodulin-binding motif TPR_2 PF07719.17 KEG12532.1 - 2.5 8.4 4.0 12 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DBP10CT PF08147.12 KEG12533.1 - 4.2e-11 42.9 3.1 1.1e-10 41.6 3.1 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DUF5089 PF17002.5 KEG12533.1 - 0.00046 20.1 0.5 0.00046 20.1 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) Alb1 PF09135.11 KEG12533.1 - 9.9 7.1 16.2 0.26 12.2 7.6 2.2 1 1 1 2 2 2 0 Alb1 dsrm PF00035.26 KEG12534.1 - 1.2e-08 35.6 0.1 0.077 13.7 0.1 4.9 4 0 0 4 4 4 2 Double-stranded RNA binding motif SYS1 PF09801.9 KEG12535.1 - 1.5e-35 122.5 5.8 1.9e-35 122.1 5.8 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network EMP70 PF02990.16 KEG12536.1 - 4e-160 533.9 8.8 4.7e-160 533.7 8.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Ycf4 PF02392.16 KEG12536.1 - 0.033 13.8 4.5 0.088 12.4 4.5 1.7 1 0 0 1 1 1 0 Ycf4 DUF4083 PF13314.6 KEG12536.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) DUF4726 PF15855.5 KEG12538.1 - 0.25 11.6 2.3 2.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) ubiquitin PF00240.23 KEG12539.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family UBA PF00627.31 KEG12540.1 - 3.1e-10 39.8 0.0 1.1e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain XPC-binding PF09280.11 KEG12540.1 - 7e-07 28.9 5.2 7e-07 28.9 5.2 2.1 1 1 1 2 2 2 1 XPC-binding domain DUF2969 PF11184.8 KEG12540.1 - 0.06 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) PcrB PF01884.17 KEG12540.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 PcrB family RabGAP-TBC PF00566.18 KEG12542.1 - 6.9e-46 156.6 0.0 1.2e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Tti2 PF10521.9 KEG12542.1 - 0.54 9.7 3.6 11 5.5 0.2 2.2 2 0 0 2 2 2 0 Tti2 family Nodulin-like PF06813.13 KEG12546.1 - 9.2e-10 38.4 13.6 1.1e-09 38.2 13.6 1.0 1 0 0 1 1 1 1 Nodulin-like DUF2427 PF10348.9 KEG12546.1 - 0.022 14.6 0.7 0.048 13.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) MotA_ExbB PF01618.16 KEG12546.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.3 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF4788 PF16032.5 KEG12547.1 - 0.00099 18.1 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4788) FAM184 PF15665.5 KEG12549.1 - 0.0034 17.2 6.6 0.0034 17.2 6.6 5.1 4 1 1 5 5 5 1 Family with sequence similarity 184, A and B Peptidase_C1 PF00112.23 KEG12550.1 - 1.7e-58 198.2 3.8 2.3e-58 197.9 3.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KEG12550.1 - 3.2e-11 43.5 0.1 5e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KEG12550.1 - 0.033 13.0 0.3 0.067 11.9 0.1 1.5 2 0 0 2 2 2 0 Peptidase C1-like family fragilysinNterm PF16376.5 KEG12551.1 - 0.051 13.3 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin ASPRs PF17641.2 KEG12551.1 - 0.24 11.7 4.2 0.87 9.9 0.2 3.0 2 0 0 2 2 2 0 Ancylostoma-associated secreted protein related DFP PF04127.15 KEG12552.1 - 0.081 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Raf1_HTH PF18579.1 KEG12554.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Pkinase PF00069.25 KEG12558.1 - 1.9e-24 86.5 0.0 3.7e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12558.1 - 1.6e-12 47.3 0.0 2.5e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KEG12558.1 - 0.0027 16.8 0.1 0.0034 16.5 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KEG12558.1 - 0.0073 15.1 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG12558.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Got1 PF04178.12 KEG12559.1 - 4.4e-28 98.0 12.9 5.6e-28 97.6 12.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Hid1 PF12722.7 KEG12559.1 - 0.043 12.0 0.6 0.057 11.5 0.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4227 PF14004.6 KEG12559.1 - 0.45 10.5 3.2 7.3 6.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) ABC_membrane PF00664.23 KEG12560.1 - 5.6e-95 318.1 30.7 4.2e-53 180.8 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEG12560.1 - 3e-69 231.8 0.0 1.9e-33 115.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEG12560.1 - 2.5e-11 43.4 0.0 0.00024 20.6 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KEG12560.1 - 6.3e-09 35.4 0.0 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 KEG12560.1 - 1.4e-07 32.0 0.1 0.031 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEG12560.1 - 1.6e-05 25.2 5.9 0.22 11.8 0.9 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEG12560.1 - 3.8e-05 23.4 0.2 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEG12560.1 - 5.9e-05 23.0 0.4 0.66 9.7 0.1 4.1 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KEG12560.1 - 8.2e-05 23.0 0.8 1 9.8 0.7 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KEG12560.1 - 0.00023 21.1 0.0 0.92 9.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 KEG12560.1 - 0.00049 20.3 4.6 0.83 9.9 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KEG12560.1 - 0.00062 19.7 0.1 0.1 12.5 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain MeaB PF03308.16 KEG12560.1 - 0.00063 18.8 0.1 0.27 10.2 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KEG12560.1 - 0.00073 20.1 1.1 1.1 9.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 KEG12560.1 - 0.00073 19.3 0.0 0.55 9.8 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.18 KEG12560.1 - 0.00086 19.1 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KEG12560.1 - 0.00095 18.9 0.2 1.9 8.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 KEG12560.1 - 0.002 18.1 0.2 0.98 9.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KEG12560.1 - 0.0022 17.2 0.0 0.74 8.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 KEG12560.1 - 0.0025 18.4 0.0 3.1 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 KEG12560.1 - 0.0058 15.5 0.1 0.9 8.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KEG12560.1 - 0.007 16.0 0.0 11 5.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 KEG12560.1 - 0.0093 15.7 0.0 4.7 6.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KEG12560.1 - 0.0097 15.9 0.0 1.7 8.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_7 PF12775.7 KEG12560.1 - 0.01 15.4 0.2 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KEG12560.1 - 0.014 15.5 0.6 3.2 7.8 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain APS_kinase PF01583.20 KEG12560.1 - 0.019 14.8 0.1 0.36 10.7 0.0 2.7 3 0 0 3 3 2 0 Adenylylsulphate kinase T2SSE PF00437.20 KEG12560.1 - 0.034 13.2 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KEG12560.1 - 0.048 14.1 0.0 7.2 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KEG12560.1 - 0.087 12.5 0.3 2.3 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KEG12560.1 - 0.1 12.7 0.4 41 4.3 0.1 3.3 4 0 0 4 4 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KEG12560.1 - 0.13 11.9 0.1 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KEG12560.1 - 0.16 12.2 0.6 10 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEG12560.1 - 0.17 11.0 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) 7tm_7 PF08395.12 KEG12560.1 - 0.17 11.1 3.9 0.039 13.2 0.3 1.7 2 0 0 2 2 1 0 7tm Chemosensory receptor AAA_17 PF13207.6 KEG12560.1 - 0.19 12.1 0.1 34 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain MoaE PF02391.17 KEG12560.1 - 0.2 12.0 0.1 9 6.6 0.0 2.7 2 0 0 2 2 2 0 MoaE protein Cauli_DNA-bind PF03310.13 KEG12561.1 - 0.00021 21.3 2.2 0.00021 21.3 2.2 3.5 2 1 2 4 4 4 1 Caulimovirus DNA-binding protein TPD52 PF04201.15 KEG12561.1 - 0.0033 17.1 7.1 0.0033 17.1 7.1 6.1 1 1 2 6 6 6 1 Tumour protein D52 family Mga PF05043.13 KEG12561.1 - 0.063 13.9 2.2 0.4 11.3 0.3 3.0 1 1 1 2 2 2 0 Mga helix-turn-helix domain DUF4578 PF15147.6 KEG12561.1 - 0.59 11.0 0.0 0.59 11.0 0.0 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF4578) HECT PF00632.25 KEG12562.1 - 9.1e-12 45.1 0.0 3.5e-05 23.5 0.0 3.2 3 0 0 3 3 3 3 HECT-domain (ubiquitin-transferase) RT_RNaseH_2 PF17919.1 KEG12562.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Rio2_N PF09202.11 KEG12563.1 - 0.11 12.8 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Rio2, N-terminal CECR6_TMEM121 PF14997.6 KEG12565.1 - 1.8e-07 31.2 5.4 7.4e-07 29.2 0.3 3.0 3 0 0 3 3 3 2 CECR6/TMEM121 family Spc7 PF08317.11 KEG12566.1 - 0.0019 17.1 1.9 0.0043 16.0 1.9 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Flg_hook PF02120.16 KEG12566.1 - 0.013 15.4 0.1 0.11 12.5 0.1 2.6 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK ubiquitin PF00240.23 KEG12566.1 - 0.02 14.6 0.1 0.068 12.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family Bacillus_HBL PF05791.11 KEG12566.1 - 0.028 14.2 1.0 0.054 13.3 1.0 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 KEG12566.1 - 0.072 13.1 0.3 0.072 13.1 0.3 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dor1 PF04124.12 KEG12566.1 - 0.24 10.1 2.1 0.39 9.3 2.1 1.2 1 0 0 1 1 1 0 Dor1-like family Jnk-SapK_ap_N PF09744.9 KEG12566.1 - 0.88 9.8 6.3 0.1 12.8 1.2 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-CSL PF05207.13 KEG12567.1 - 2.7e-14 52.6 0.2 3.6e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KEG12567.1 - 0.027 14.6 0.4 0.054 13.6 0.4 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Synaptobrevin PF00957.21 KEG12568.1 - 3.5e-21 74.8 2.7 5.2e-21 74.2 2.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEG12568.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Prominin PF05478.11 KEG12568.1 - 0.013 13.6 0.3 0.017 13.1 0.3 1.1 1 0 0 1 1 1 0 Prominin Vac7 PF12751.7 KEG12568.1 - 0.018 14.5 0.6 0.023 14.1 0.6 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 zf_Hakai PF18408.1 KEG12568.1 - 0.02 14.6 0.4 0.063 13.0 0.4 1.9 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain FAD_binding_3 PF01494.19 KEG12569.1 - 3.9e-10 39.5 0.1 4.9e-05 22.7 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEG12569.1 - 1.3e-06 28.6 0.1 5.7e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEG12569.1 - 3e-06 26.7 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEG12569.1 - 1.4e-05 24.9 0.2 0.00016 21.4 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEG12569.1 - 4.6e-05 22.7 0.1 0.00022 20.4 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEG12569.1 - 0.00022 21.7 0.0 0.00049 20.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEG12569.1 - 0.0028 16.7 0.0 0.018 14.1 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 KEG12569.1 - 0.052 12.7 0.0 0.32 10.1 0.1 2.2 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEG12569.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HTH_Tnp_Mu_2 PF09039.11 KEG12571.1 - 0.017 15.2 0.2 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain DUF4962 PF16332.5 KEG12571.1 - 0.14 10.6 0.4 0.22 10.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) DUF2802 PF10975.8 KEG12571.1 - 6.4 7.0 11.7 3.8 7.7 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) bZIP_Maf PF03131.17 KEG12571.1 - 8.2 7.0 10.6 3.4 8.3 1.4 3.6 3 1 0 3 3 3 0 bZIP Maf transcription factor PCI PF01399.27 KEG12575.1 - 1.8e-05 25.2 0.0 2.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain APG6_N PF17675.1 KEG12576.1 - 0.00023 21.7 4.0 0.00023 21.7 4.0 5.2 5 2 1 6 6 6 3 Apg6 coiled-coil region bZIP_1 PF00170.21 KEG12576.1 - 0.0068 16.5 29.2 0.0071 16.4 0.4 5.8 6 0 0 6 6 6 3 bZIP transcription factor STALD PF18185.1 KEG12576.1 - 0.021 14.1 0.4 2.5 7.4 0.1 2.7 2 1 1 3 3 3 0 Sir2- and TIR-associating SLOG family Rootletin PF15035.6 KEG12576.1 - 0.12 12.4 0.1 0.12 12.4 0.1 5.0 3 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KEG12576.1 - 0.49 10.4 47.7 0.087 12.8 9.0 6.0 6 0 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KEG12576.1 - 0.86 9.8 56.1 0.11 12.7 1.2 6.0 4 2 1 5 5 5 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KEG12576.1 - 2.9 7.4 36.6 1.8 8.1 5.7 3.3 2 1 1 3 3 3 0 Exonuclease VII, large subunit Fcf2 PF08698.11 KEG12577.1 - 6.7e-05 23.2 9.7 7.2e-05 23.1 5.3 2.9 1 1 1 2 2 2 2 Fcf2 pre-rRNA processing BORCS8 PF10167.9 KEG12578.1 - 2.5e-05 24.2 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 RapA_C PF12137.8 KEG12578.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal zf_C2H2_13 PF18508.1 KEG12579.1 - 0.01 15.4 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger domain DUF1308 PF07000.11 KEG12580.1 - 2.4e-14 53.6 0.0 6.8e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KEG12580.1 - 8e-05 22.0 0.4 0.00014 21.3 0.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5614) DDE_Tnp_1 PF01609.21 KEG12580.1 - 0.39 10.3 1.9 0.78 9.3 1.9 1.4 1 0 0 1 1 1 0 Transposase DDE domain zf-RING_2 PF13639.6 KEG12581.1 - 5.8e-10 39.3 8.5 2.5e-09 37.3 8.5 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEG12581.1 - 1.3e-08 34.4 6.1 3.8e-08 32.9 6.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEG12581.1 - 4.7e-06 26.4 10.0 1.7e-05 24.5 10.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEG12581.1 - 3.3e-05 24.1 6.9 3.3e-05 24.1 6.9 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEG12581.1 - 0.00017 21.5 6.5 0.00017 21.5 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KEG12581.1 - 0.00042 20.3 3.7 0.00096 19.2 3.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KEG12581.1 - 0.0015 18.4 8.5 0.0056 16.5 8.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEG12581.1 - 0.0023 17.8 6.3 0.0023 17.8 6.3 2.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 KEG12581.1 - 0.0046 17.1 0.9 0.011 15.8 0.9 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_10 PF16685.5 KEG12581.1 - 0.013 15.7 1.6 0.013 15.7 1.6 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 PHD PF00628.29 KEG12581.1 - 0.021 14.7 9.3 0.2 11.6 8.2 2.6 2 0 0 2 2 2 0 PHD-finger zf-C3H2C3 PF17122.5 KEG12581.1 - 0.036 14.1 4.6 0.12 12.4 4.6 2.0 1 0 0 1 1 1 0 Zinc-finger zf-HC5HC2H PF13771.6 KEG12581.1 - 0.06 13.6 2.3 0.19 12.0 2.3 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.6 KEG12581.1 - 0.24 11.5 12.8 0.049 13.7 5.7 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KEG12581.1 - 0.69 9.8 7.0 2.9 7.8 7.0 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SPRY PF00622.28 KEG12582.1 - 4.6e-10 39.7 0.0 8.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain B9-C2 PF07162.11 KEG12583.1 - 4.1e-44 150.8 0.1 4.9e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein BRCT_2 PF16589.5 KEG12584.1 - 0.0049 17.2 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Diphthami_syn_2 PF01902.17 KEG12586.1 - 1.5e-29 103.0 0.0 1.6e-28 99.7 0.0 2.1 1 1 0 1 1 1 1 Diphthamide synthase YTH PF04146.15 KEG12587.1 - 3.1e-05 24.0 0.0 0.0002 21.4 0.0 1.9 1 1 1 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 KEG12587.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomyosin_1 PF12718.7 KEG12588.1 - 0.0069 16.6 0.8 0.0069 16.6 0.8 3.4 3 1 0 3 3 3 1 Tropomyosin like Fib_alpha PF08702.10 KEG12588.1 - 0.18 12.0 10.1 2.9 8.1 0.2 3.9 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 KEG12588.1 - 5 7.5 16.3 0.27 11.6 3.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sec2p PF06428.11 KEG12588.1 - 6.4 6.8 17.1 1.6 8.8 2.6 4.1 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p RIC3 PF15361.6 KEG12588.1 - 9.3 6.6 6.3 1.9 8.9 0.7 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 MADF_DNA_bdg PF10545.9 KEG12589.1 - 0.31 11.4 8.4 1.5 9.2 0.2 3.9 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Dynein_light PF01221.18 KEG12590.1 - 1.1e-34 118.6 1.0 1.2e-34 118.5 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 KEG12590.1 - 0.14 12.1 0.3 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 Ectatomin zf-NOSIP PF15906.5 KEG12591.1 - 0.024 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 KEG12591.1 - 0.037 14.2 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 U-box domain FliJ PF02050.16 KEG12591.1 - 0.064 13.5 0.7 0.064 13.5 0.7 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein TCR PF03638.15 KEG12591.1 - 4.2 7.8 7.7 0.38 11.1 3.3 1.6 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Pox_Ag35 PF03286.14 KEG12592.1 - 1.8 8.4 10.5 2 8.2 10.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UPF0016 PF01169.19 KEG12594.1 - 2e-43 146.6 21.8 1.4e-21 76.5 6.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 KEG12594.1 - 0.048 13.3 4.3 0.41 10.3 0.3 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family Chloroplast_duf PF14476.6 KEG12594.1 - 0.17 10.9 0.8 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 Petal formation-expressed ABC_transp_aux PF09822.9 KEG12595.1 - 2.1e-05 24.2 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 KEG12595.1 - 0.029 14.8 0.0 0.097 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) ThuA PF06283.11 KEG12595.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Trehalose utilisation DUF4159 PF13709.6 KEG12595.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) WD40 PF00400.32 KEG12596.1 - 4.5e-09 36.8 16.3 0.0013 19.5 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG12596.1 - 0.0068 16.7 1.0 13 6.2 0.0 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1143 PF06608.11 KEG12597.1 - 0.00086 19.4 0.1 0.0019 18.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1143) EF-hand_6 PF13405.6 KEG12597.1 - 0.0017 18.1 0.1 13 6.1 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KEG12597.1 - 0.003 17.4 0.3 1.9 8.4 0.0 3.6 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_7 PF13499.6 KEG12597.1 - 0.0035 17.8 0.1 0.059 13.8 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG12597.1 - 0.032 13.8 2.3 18 5.1 0.0 4.4 5 0 0 5 5 5 0 EF hand Sigma70_r1_1 PF03979.14 KEG12597.1 - 0.14 12.2 0.6 0.42 10.7 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Radical_SAM PF04055.21 KEG12598.1 - 4.9e-11 43.3 0.1 7.3e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 KEG12598.1 - 6.8e-10 39.3 0.1 1.8e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pkinase PF00069.25 KEG12599.1 - 1.5e-31 109.8 0.3 3.4e-18 66.0 0.0 4.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12599.1 - 0.00097 18.5 2.5 1.7 7.8 0.2 4.3 4 0 0 4 4 4 2 Protein tyrosine kinase RIO1 PF01163.22 KEG12599.1 - 0.028 14.0 0.0 0.089 12.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF3709 PF12493.8 KEG12599.1 - 0.099 12.7 0.2 0.3 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) Bac_small_YrzI PF09501.10 KEG12599.1 - 3.7 7.7 5.3 0.46 10.7 0.6 1.9 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DUF4028 PF13220.6 KEG12600.1 - 0.17 11.7 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) WD40 PF00400.32 KEG12603.1 - 0.022 15.6 1.1 0.1 13.5 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat US2 PF02476.15 KEG12603.1 - 0.073 13.8 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 US2 family BBP1_C PF15272.6 KEG12603.1 - 1.6 8.6 6.7 0.16 11.8 2.1 1.6 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Peptidase_M8 PF01457.16 KEG12605.1 - 7.5e-111 371.4 5.7 9.9e-60 202.7 5.9 2.1 2 0 0 2 2 2 2 Leishmanolysin Reprolysin_5 PF13688.6 KEG12605.1 - 0.00026 21.2 0.0 0.00057 20.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 TBP PF00352.21 KEG12609.1 - 0.081 12.9 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) PP2C PF00481.21 KEG12610.1 - 2.6e-31 109.2 0.0 3.4e-30 105.5 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEG12610.1 - 0.042 13.8 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.16 KEG12611.1 - 1.6e-46 157.4 0.2 2e-46 157.1 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 UCR_UQCRX_QCR9 PF05365.12 KEG12611.1 - 0.15 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Oxidored_FMN PF00724.20 KEG12613.1 - 9.3e-40 136.9 0.0 1.2e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KEG12613.1 - 1e-17 64.3 0.0 5.2e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG12613.1 - 8.1e-10 38.8 0.1 3.3e-09 36.8 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEG12613.1 - 7e-07 28.9 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEG12613.1 - 1e-06 29.2 0.2 0.001 19.6 0.3 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEG12613.1 - 3.4e-06 26.0 0.2 1.9e-05 23.6 0.1 2.2 1 1 1 2 2 2 1 HI0933-like protein DAO PF01266.24 KEG12613.1 - 9.8e-06 25.4 2.2 8.1e-05 22.4 2.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEG12613.1 - 1.1e-05 24.8 1.2 2.6e-05 23.5 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEG12613.1 - 0.00087 18.6 0.0 0.011 15.0 0.0 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEG12613.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMO-like PF00743.19 KEG12613.1 - 0.0027 16.2 0.1 0.73 8.2 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Thi4 PF01946.17 KEG12613.1 - 0.003 16.8 0.1 0.007 15.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KEG12613.1 - 0.0033 16.6 0.9 0.005 16.0 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KEG12613.1 - 0.0074 15.9 0.7 0.04 13.5 0.6 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KEG12613.1 - 0.061 13.3 0.2 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KEG12613.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KEG12613.1 - 0.075 12.9 0.7 0.27 11.1 0.2 2.1 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEG12613.1 - 0.083 13.0 0.0 5.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEG12613.1 - 0.19 11.7 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribosomal_L37e PF01907.19 KEG12613.1 - 0.67 10.2 2.4 2.3 8.5 2.4 1.8 1 0 0 1 1 1 0 Ribosomal protein L37e TLD PF07534.16 KEG12614.1 - 3.6e-11 43.4 0.0 5.1e-06 26.8 0.0 3.0 2 1 0 2 2 2 2 TLD SIS PF01380.22 KEG12615.1 - 7.2e-56 187.6 0.1 4.1e-30 104.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KEG12615.1 - 1.3e-15 57.8 0.0 4.9e-15 55.9 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEG12615.1 - 1.7e-09 37.6 0.0 4.9e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KEG12615.1 - 6.7e-05 21.9 0.0 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KEG12615.1 - 0.00062 19.8 0.0 0.19 11.7 0.0 3.2 2 1 1 3 3 3 1 SIS domain DDR_swiveling PF18427.1 KEG12615.1 - 0.0061 16.6 0.1 0.022 14.8 0.1 1.9 1 1 1 2 2 2 1 DD-reactivating factor swiveling domain RANK_CRD_2 PF18278.1 KEG12615.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Mob1_phocein PF03637.17 KEG12616.1 - 7.6e-68 227.8 0.1 9.7e-68 227.5 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Ntox8 PF15545.6 KEG12616.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 8 Thiolase_N PF00108.23 KEG12617.1 - 1e-60 205.3 0.6 3.3e-60 203.6 0.6 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEG12617.1 - 4.7e-35 119.9 0.0 1.2e-34 118.6 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEG12617.1 - 4.5e-08 33.0 0.3 2e-07 30.9 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KEG12617.1 - 0.0012 17.6 0.1 0.0023 16.7 0.1 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KEG12617.1 - 0.053 13.4 0.5 0.053 13.4 0.5 2.8 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NTPase_I-T PF01931.18 KEG12618.1 - 1.9e-52 177.4 0.0 2.1e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 TP_methylase PF00590.20 KEG12619.1 - 9.4e-23 81.3 0.1 1.5e-22 80.6 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L36 PF00444.18 KEG12620.1 - 0.00069 19.8 0.3 0.00069 19.8 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L36 Cmc1 PF08583.10 KEG12621.1 - 0.0065 16.5 3.0 0.012 15.6 3.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF588 PF04535.12 KEG12623.1 - 0.067 13.0 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF1499 PF07386.11 KEG12624.1 - 0.064 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) L51_S25_CI-B8 PF05047.16 KEG12625.1 - 1.5e-06 28.0 0.0 4.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.25 KEG12627.1 - 8.6e-47 159.7 0.0 6.1e-46 156.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12627.1 - 9.2e-34 116.9 0.0 8.1e-31 107.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH_3 PF14593.6 KEG12627.1 - 2.5e-18 66.1 0.0 4.1e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KEG12627.1 - 7.6e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG12627.1 - 0.036 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PD-C2-AF1 PF09310.10 KEG12628.1 - 0.26 10.7 7.3 0.41 10.0 7.3 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 HEAT PF02985.22 KEG12633.1 - 1.3e-21 74.8 17.8 0.0068 16.6 0.0 10.0 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 KEG12633.1 - 2.9e-16 59.6 6.1 3.7e-05 24.0 0.4 5.9 3 1 2 5 5 5 4 HEAT repeats Cnd1 PF12717.7 KEG12633.1 - 0.00021 21.4 4.0 0.026 14.6 0.3 4.2 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEG12633.1 - 0.0029 18.2 6.3 0.043 14.4 0.3 5.0 5 1 2 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KEG12633.1 - 0.0051 16.4 0.5 4 6.9 0.0 3.5 4 0 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.20 KEG12633.1 - 0.023 13.3 3.5 0.16 10.5 0.4 2.6 3 0 0 3 3 3 0 Adaptin N terminal region DUF3730 PF12530.8 KEG12633.1 - 0.18 11.3 3.6 0.19 11.2 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3730) API5 PF05918.11 KEG12633.1 - 0.61 8.8 1.2 1.5 7.6 1.1 1.5 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ATP-gua_Ptrans PF00217.19 KEG12635.1 - 1.1e-85 286.5 0.2 1.9e-85 285.6 0.0 1.4 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KEG12635.1 - 2.2e-32 111.3 0.2 7.8e-31 106.3 0.0 2.3 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain CsbD PF05532.12 KEG12635.1 - 0.071 13.0 1.3 34 4.4 0.1 3.4 3 0 0 3 3 3 0 CsbD-like SIR4_SID PF16991.5 KEG12635.1 - 0.095 12.8 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Sir4 SID domain ZapD PF07072.11 KEG12635.1 - 0.1 12.3 0.8 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Cell division protein NAF PF03822.14 KEG12635.1 - 0.17 12.1 0.4 23 5.3 0.0 3.4 4 0 0 4 4 4 0 NAF domain Ribonuc_2-5A PF06479.12 KEG12635.1 - 0.24 11.6 2.1 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Ribonuclease 2-5A ABC2_membrane PF01061.24 KEG12636.1 - 2.1e-38 131.8 20.0 3.4e-38 131.2 20.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KEG12636.1 - 1.9e-19 70.6 0.0 2.9e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KEG12636.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KEG12636.1 - 0.0036 17.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG12636.1 - 0.0046 16.4 0.1 0.072 12.5 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG12636.1 - 0.012 15.3 0.8 0.026 14.3 0.8 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KEG12636.1 - 0.013 15.3 0.7 0.03 14.1 0.2 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KEG12636.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KEG12636.1 - 0.037 14.3 0.0 0.2 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 KEG12636.1 - 0.054 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KEG12636.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KEG12636.1 - 0.1 12.6 0.1 0.34 10.9 0.1 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KEG12636.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 KEG12636.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KEG12636.1 - 0.17 12.3 0.0 0.97 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KEG12636.1 - 0.17 11.6 0.3 0.36 10.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEG12636.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 KEG12636.1 - 0.19 10.9 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC2_membrane_3 PF12698.7 KEG12636.1 - 1.9 7.5 20.0 0.11 11.6 14.1 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein SAP18 PF06487.12 KEG12637.1 - 0.016 15.4 0.5 0.048 13.8 0.0 2.1 3 0 0 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) CDC45 PF02724.14 KEG12637.1 - 0.069 11.4 0.7 0.084 11.2 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Inositol_P PF00459.25 KEG12638.1 - 3e-29 102.4 0.1 8.2e-29 101.0 0.1 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 KEG12639.1 - 1.4e-16 60.4 31.6 6.4e-14 51.6 25.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG12639.1 - 8.2e-06 24.9 0.7 8.2e-06 24.9 0.7 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter HTH_CodY PF08222.11 KEG12639.1 - 0.21 11.2 0.8 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 CodY helix-turn-helix domain DUF1440 PF07274.12 KEG12639.1 - 0.49 10.7 6.0 12 6.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1440) MFS_2 PF13347.6 KEG12639.1 - 1.5 7.3 31.9 0.014 14.0 10.4 3.1 2 2 1 3 3 3 0 MFS/sugar transport protein MFS_1 PF07690.16 KEG12640.1 - 1.8e-10 40.3 32.8 9.8e-07 28.0 13.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3331 PF11811.8 KEG12640.1 - 0.12 12.2 0.3 0.36 10.7 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) Gastrin PF00918.17 KEG12641.1 - 4.1 8.4 7.1 1.8 9.5 0.3 2.3 1 1 0 2 2 2 0 Gastrin/cholecystokinin family DUF4550 PF15084.6 KEG12642.1 - 0.19 12.1 0.1 0.37 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) Nuc_sug_transp PF04142.15 KEG12643.1 - 5.1e-36 124.4 21.3 1.2e-35 123.2 21.3 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KEG12643.1 - 4.7e-10 39.8 30.4 8.3e-05 22.8 9.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family Fez1 PF06818.15 KEG12644.1 - 1.3 9.4 32.2 0.33 11.4 10.5 2.4 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KEG12644.1 - 2.3 7.0 26.9 0.4 9.5 15.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 KEG12644.1 - 2.6 8.8 14.0 9.9 6.9 3.9 3.7 1 1 3 4 4 4 0 Initiation control protein YabA DUF1664 PF07889.12 KEG12644.1 - 5.2 7.1 10.2 3.2 7.8 5.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Mem_trans PF03547.18 KEG12645.1 - 5.9e-25 87.5 14.9 1.6e-24 86.1 14.9 1.5 1 1 0 1 1 1 1 Membrane transport protein Kinesin PF00225.23 KEG12646.1 - 0.0037 16.2 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain GDP_Man_Dehyd PF16363.5 KEG12647.1 - 1.6e-150 501.1 0.0 1.8e-150 500.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEG12647.1 - 1.5e-73 247.3 0.0 1.8e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEG12647.1 - 2.4e-06 26.9 0.0 3.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEG12647.1 - 1e-05 24.8 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEG12647.1 - 6.9e-05 22.8 0.0 0.00014 21.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KEG12647.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family SRP_TPR_like PF17004.5 KEG12648.1 - 4.3e-12 46.1 11.1 1.2e-11 44.7 2.9 3.2 2 1 2 4 4 4 1 Putative TPR-like repeat TPR_19 PF14559.6 KEG12648.1 - 1.7e-10 41.2 27.4 0.011 16.3 0.5 7.6 6 1 0 7 7 7 3 Tetratricopeptide repeat SRP72 PF08492.12 KEG12648.1 - 6.8e-08 32.8 0.5 6.8e-08 32.8 0.5 2.8 3 0 0 3 3 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 KEG12648.1 - 4.1e-07 30.1 19.6 1.5e-05 25.1 2.3 5.3 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KEG12648.1 - 3.8e-05 24.3 25.1 0.12 13.0 2.8 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12648.1 - 0.00057 20.5 30.3 2.1 9.4 0.6 8.3 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG12648.1 - 0.0081 16.7 19.4 0.92 10.3 2.1 6.5 7 0 0 7 7 5 1 Tetratricopeptide repeat Transglut_core2 PF13369.6 KEG12648.1 - 0.063 12.8 0.5 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 Transglutaminase-like superfamily TPR_7 PF13176.6 KEG12648.1 - 0.13 12.4 12.6 0.13 12.3 1.3 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG12648.1 - 0.13 12.0 1.3 3.3 7.5 0.3 3.2 2 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KEG12648.1 - 0.53 10.2 11.5 0.36 10.7 1.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG12648.1 - 0.54 10.4 8.5 5.2 7.2 0.1 3.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KEG12648.1 - 0.61 10.3 26.0 0.12 12.6 1.4 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12648.1 - 0.93 9.9 12.5 2.8 8.4 1.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG12648.1 - 2.1 8.7 29.0 0.075 13.3 4.1 4.7 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12648.1 - 7.5 6.9 27.8 0.72 10.1 2.3 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ABC_tran PF00005.27 KEG12649.1 - 1e-43 149.1 0.0 1.6e-21 77.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KEG12649.1 - 2.2e-20 72.4 3.0 2.2e-20 72.4 3.0 3.3 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KEG12649.1 - 2.2e-19 70.4 5.2 3.8e-05 23.7 0.0 4.3 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG12649.1 - 1.1e-10 41.3 1.0 0.0025 17.3 0.1 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KEG12649.1 - 5.1e-07 30.2 0.0 0.0075 16.7 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG12649.1 - 6.3e-07 29.9 0.0 0.005 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KEG12649.1 - 9.6e-07 29.4 0.6 0.091 13.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KEG12649.1 - 1.1e-06 28.9 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEG12649.1 - 1.2e-06 28.5 0.0 0.054 13.2 0.1 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KEG12649.1 - 3.1e-06 27.4 0.3 0.035 14.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KEG12649.1 - 7.2e-06 25.6 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEG12649.1 - 7.5e-06 26.3 0.0 0.028 14.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 KEG12649.1 - 2.5e-05 24.9 10.4 0.015 15.8 1.4 3.4 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KEG12649.1 - 4.3e-05 23.5 0.3 0.051 13.6 0.0 2.9 2 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KEG12649.1 - 6.9e-05 22.9 0.0 1.6 8.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KEG12649.1 - 8.4e-05 22.2 0.0 0.57 9.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KEG12649.1 - 0.00015 21.7 0.1 0.0047 16.9 0.0 2.8 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KEG12649.1 - 0.00021 21.3 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 KEG12649.1 - 0.00026 21.3 1.4 0.12 12.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KEG12649.1 - 0.00026 20.8 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEG12649.1 - 0.00034 20.6 0.1 0.67 9.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Rad17 PF03215.15 KEG12649.1 - 0.00054 19.9 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KEG12649.1 - 0.0007 19.2 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KEG12649.1 - 0.00099 19.2 0.1 1.2 9.3 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KEG12649.1 - 0.0021 17.8 0.0 0.58 9.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KEG12649.1 - 0.0036 17.1 1.3 0.72 9.5 0.0 3.2 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KEG12649.1 - 0.0058 15.8 0.0 2.4 7.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_13 PF13166.6 KEG12649.1 - 0.0069 15.1 0.7 2.3 6.8 0.0 3.6 3 1 0 3 3 3 1 AAA domain dNK PF01712.19 KEG12649.1 - 0.007 16.2 0.0 0.65 9.8 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase Mg_chelatase PF01078.21 KEG12649.1 - 0.0086 15.5 0.0 5.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEG12649.1 - 0.01 15.6 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KEG12649.1 - 0.012 15.5 0.0 3.1 7.7 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 KEG12649.1 - 0.013 15.1 0.0 4.4 6.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 KEG12649.1 - 0.015 14.5 0.0 3.9 6.5 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 KEG12649.1 - 0.018 15.2 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KEG12649.1 - 0.019 14.3 0.0 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KEG12649.1 - 0.023 14.3 0.1 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KEG12649.1 - 0.026 14.5 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 KEG12649.1 - 0.029 14.1 0.0 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 KEG12649.1 - 0.077 13.4 0.0 19 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KEG12649.1 - 0.097 11.6 0.4 4.4 6.2 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin PF02224.18 KEG12649.1 - 0.1 12.3 0.4 5.2 6.7 0.0 2.7 2 1 0 2 2 2 0 Cytidylate kinase ATP-synt_ab PF00006.25 KEG12649.1 - 0.11 12.1 0.0 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 KEG12649.1 - 0.12 12.0 3.4 1.7 8.2 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KEG12649.1 - 0.18 12.1 0.3 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Vps53_N PF04100.12 KEG12652.1 - 7.8e-65 219.3 3.7 1.1e-64 218.8 3.7 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal COG7 PF10191.9 KEG12652.1 - 0.0015 16.9 1.2 0.0027 16.0 1.2 1.4 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG2 PF06148.11 KEG12652.1 - 0.0047 17.0 2.2 0.017 15.2 1.1 2.5 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KEG12652.1 - 0.028 13.3 3.2 0.054 12.4 3.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 KEG12652.1 - 0.038 13.5 0.8 0.069 12.6 0.8 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3626 PF12294.8 KEG12652.1 - 0.041 12.9 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) AKAP7_RIRII_bdg PF10470.9 KEG12652.1 - 0.14 12.3 0.5 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein LXG PF04740.12 KEG12652.1 - 0.16 11.6 2.3 0.39 10.4 2.3 1.6 1 0 0 1 1 1 0 LXG domain of WXG superfamily XhlA PF10779.9 KEG12652.1 - 0.42 10.8 5.5 0.31 11.3 1.7 2.5 1 1 2 3 3 3 0 Haemolysin XhlA DUF4337 PF14235.6 KEG12652.1 - 0.47 10.6 2.6 0.95 9.6 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Arf PF00025.21 KEG12654.1 - 2e-41 141.3 0.0 2.3e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KEG12654.1 - 1.4e-17 63.8 0.0 1.7e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG12654.1 - 8.3e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KEG12654.1 - 2.4e-08 33.6 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG12654.1 - 4.4e-08 33.2 0.0 1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KEG12654.1 - 1.4e-06 27.8 0.0 0.00012 21.3 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 KEG12654.1 - 5.1e-06 26.0 0.0 6.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 KEG12654.1 - 4.5e-05 23.4 0.4 0.0019 18.2 0.4 2.2 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KEG12654.1 - 0.008 16.7 0.0 0.0098 16.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter cobW PF02492.19 KEG12654.1 - 0.0085 15.7 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KEG12654.1 - 0.045 14.2 0.1 0.091 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG12654.1 - 0.047 13.3 0.3 0.082 12.5 0.1 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 KEG12654.1 - 0.05 13.1 0.0 0.73 9.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KEG12654.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEG12654.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KEG12654.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KEG12654.1 - 0.12 12.3 0.1 4 7.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KEG12654.1 - 0.15 11.6 0.6 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 Ferrous iron transport protein B CAP_GLY PF01302.25 KEG12655.1 - 7.5e-19 67.5 0.1 1.2e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Lipase PF00151.19 KEG12655.1 - 0.13 11.5 2.7 0.2 10.9 2.7 1.2 1 0 0 1 1 1 0 Lipase Dynein_light PF01221.18 KEG12657.1 - 6.2e-28 96.9 0.0 9.1e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 KEG12657.1 - 0.024 15.3 0.0 0.034 14.8 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain DUF4366 PF14283.6 KEG12657.1 - 0.15 12.1 0.1 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) FKBP_C PF00254.28 KEG12658.1 - 7.6e-24 83.9 0.0 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4576 PF15144.6 KEG12658.1 - 0.038 13.9 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) FKBP_C PF00254.28 KEG12659.1 - 8.5e-07 29.2 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RskA PF10099.9 KEG12659.1 - 0.026 14.8 0.3 0.026 14.8 0.3 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Importin_rep_4 PF18808.1 KEG12659.1 - 0.24 11.7 2.6 0.53 10.6 2.6 1.5 1 0 0 1 1 1 0 Importin repeat ARL2_Bind_BART PF11527.8 KEG12661.1 - 0.041 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART SMN PF06003.12 KEG12661.1 - 3.7 6.7 8.3 0.43 9.8 2.5 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Clathrin PF00637.20 KEG12663.1 - 5.6e-11 42.5 1.7 0.0018 18.1 0.0 5.6 5 1 0 5 5 5 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KEG12663.1 - 4.8e-06 26.8 0.2 0.78 10.1 0.0 4.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KEG12663.1 - 1.3e-05 24.5 1.5 0.0022 17.1 0.0 3.6 3 0 0 3 3 3 1 Coatomer WD associated region Nic96 PF04097.14 KEG12663.1 - 0.00091 17.8 4.0 1.2 7.6 0.1 3.4 2 1 1 3 3 3 2 Nup93/Nic96 WD40 PF00400.32 KEG12663.1 - 0.0092 16.8 1.8 2.9 8.9 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat RPN7 PF10602.9 KEG12663.1 - 0.014 15.1 2.0 2.2 7.9 0.0 3.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 KEG12663.1 - 0.43 10.7 8.5 6.8 7.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MRI PF15325.6 KEG12663.1 - 0.48 11.5 6.8 0.22 12.6 1.7 2.8 2 0 0 2 2 2 0 Modulator of retrovirus infection LRR_8 PF13855.6 KEG12664.1 - 5.6e-13 48.5 21.0 4.5e-07 29.5 5.3 5.2 3 3 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KEG12664.1 - 3.5e-10 40.0 21.2 0.00041 20.7 0.4 4.9 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG12664.1 - 0.0072 16.3 16.9 8.5 6.7 0.2 6.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KEG12664.1 - 0.6 10.9 17.5 5.2 8.0 0.1 5.8 4 1 1 5 5 5 0 Leucine Rich Repeat B9-C2 PF07162.11 KEG12666.1 - 7e-33 114.2 0.0 8.7e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Shisa PF13908.6 KEG12667.1 - 8.6 6.5 9.5 34 4.6 9.5 2.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Cpn60_TCP1 PF00118.24 KEG12668.1 - 3e-157 524.2 6.4 3.4e-157 524.0 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sun2_CC2 PF18580.1 KEG12668.1 - 0.039 14.2 0.3 12 6.3 0.0 3.1 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 AAA_6 PF12774.7 KEG12669.1 - 8.6e-142 471.9 0.0 1e-140 468.4 0.0 2.7 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KEG12669.1 - 1.2e-141 473.2 0.4 1.2e-141 473.2 0.4 3.6 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KEG12669.1 - 8.8e-110 367.5 8.9 8.8e-110 367.5 8.9 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG12669.1 - 1.4e-93 313.0 0.0 1.4e-92 309.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KEG12669.1 - 3.2e-83 278.2 0.6 3.2e-83 278.2 0.6 3.6 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 KEG12669.1 - 6.5e-79 265.4 12.4 1.5e-78 264.3 12.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 KEG12669.1 - 1.2e-73 248.0 0.1 1.2e-73 248.0 0.1 2.1 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KEG12669.1 - 1.8e-67 226.4 0.9 8.5e-62 207.9 0.1 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG12669.1 - 6.6e-46 156.1 0.0 1.8e-45 154.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG12669.1 - 1.7e-32 112.0 0.0 3.8e-20 72.2 0.0 4.5 5 0 0 5 5 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KEG12669.1 - 1.3e-23 83.1 0.1 7.9e-23 80.6 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KEG12669.1 - 7e-23 81.1 0.3 5.8e-22 78.2 0.3 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KEG12669.1 - 8e-21 74.5 0.0 5.3e-07 29.7 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG12669.1 - 4.5e-07 30.4 3.4 0.16 12.4 0.0 6.1 5 1 0 6 6 4 1 AAA ATPase domain AAA_18 PF13238.6 KEG12669.1 - 5.7e-07 30.1 2.6 0.036 14.6 0.0 6.1 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 KEG12669.1 - 6.8e-07 29.8 0.2 0.094 13.1 0.0 4.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEG12669.1 - 0.00023 21.5 1.7 0.54 10.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KEG12669.1 - 0.0019 17.6 0.1 0.48 9.8 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEG12669.1 - 0.0037 17.6 0.5 40 4.6 0.0 4.8 5 0 0 5 5 4 0 RNA helicase DUF815 PF05673.13 KEG12669.1 - 0.014 14.5 1.6 0.52 9.4 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KEG12669.1 - 0.015 15.8 0.3 19 5.7 0.0 4.0 3 0 0 3 3 2 0 ABC transporter AAA_22 PF13401.6 KEG12669.1 - 0.03 14.6 12.6 1.7 8.9 0.0 6.5 8 0 0 8 8 5 0 AAA domain TsaE PF02367.17 KEG12669.1 - 0.11 12.5 0.7 19 5.3 0.0 3.3 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KEG12669.1 - 0.12 12.2 0.2 23 4.7 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KEG12669.1 - 0.17 12.1 1.4 26 5.0 0.1 3.8 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KEG12669.1 - 0.42 10.3 2.9 11 5.7 0.1 3.4 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KEG12669.1 - 0.42 10.3 9.8 1.1 8.9 0.0 4.1 5 0 0 5 5 4 0 AAA domain AAA_33 PF13671.6 KEG12669.1 - 1.7 8.8 5.1 20 5.4 0.0 4.5 5 0 0 5 5 5 0 AAA domain FliD_N PF02465.18 KEG12669.1 - 9 7.1 11.1 0.91 10.3 0.6 3.8 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus ADIP PF11559.8 KEG12669.1 - 9.7 6.3 18.0 7 6.7 4.7 3.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DNA_pol_A PF00476.20 KEG12670.1 - 1.1e-36 126.7 0.1 3.1e-36 125.2 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KEG12670.1 - 0.00022 21.0 0.0 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease TcpA PF05946.12 KEG12670.1 - 0.1 12.7 0.0 0.46 10.6 0.0 2.1 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA PH PF00169.29 KEG12671.1 - 0.00033 21.1 0.2 0.0012 19.3 0.1 2.0 2 0 0 2 2 2 1 PH domain SE PF08491.10 KEG12672.1 - 1.7e-61 207.7 0.0 2.7e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KEG12672.1 - 2.5e-06 27.0 0.0 8.8e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEG12672.1 - 0.0035 17.6 0.2 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEG12672.1 - 0.027 13.5 0.8 5.1 6.1 0.0 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEG12672.1 - 0.06 12.6 0.0 0.21 10.8 0.0 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEG12672.1 - 0.074 12.6 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase CAF1 PF04857.20 KEG12673.1 - 3.4e-69 233.5 0.6 4.4e-69 233.1 0.6 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease HECT PF00632.25 KEG12676.1 - 2.9e-55 187.9 0.0 1.2e-54 186.0 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KEG12676.1 - 2.2e-39 134.3 1.0 5.9e-17 61.9 0.0 3.8 3 0 0 3 3 3 3 SPRY domain Laminin_G_3 PF13385.6 KEG12676.1 - 3.8e-18 66.1 0.0 9.3e-09 35.6 0.0 3.1 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily zf-C3HC4_3 PF13920.6 KEG12676.1 - 0.047 13.6 0.9 0.26 11.2 0.9 2.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lectin_leg-like PF03388.13 KEG12677.1 - 1.9e-24 86.3 0.0 2.5e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PEX11 PF05648.14 KEG12678.1 - 2.9e-06 26.9 0.7 4.8e-06 26.2 0.7 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RRM PF10378.9 KEG12678.1 - 0.25 11.1 0.9 0.51 10.1 0.1 1.9 2 0 0 2 2 2 0 Putative RRM domain PI3_PI4_kinase PF00454.27 KEG12679.1 - 4.4e-66 223.2 0.0 9.4e-66 222.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KEG12679.1 - 1.4e-55 189.0 2.7 9.7e-55 186.2 3.8 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 KEG12679.1 - 2.3e-27 95.9 0.1 2.7e-21 76.1 0.0 5.4 4 1 0 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KEG12679.1 - 1.3e-19 70.4 4.4 9.9e-19 67.6 1.3 4.0 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 KEG12679.1 - 1.6e-16 59.8 0.1 5.3e-16 58.1 0.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KEG12679.1 - 0.0027 18.0 6.1 0.51 10.8 0.1 5.5 6 0 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 KEG12679.1 - 0.021 15.4 5.4 10 6.8 0.0 6.5 7 0 0 7 7 7 0 HEAT-like repeat ParcG PF10274.9 KEG12679.1 - 0.063 13.4 3.9 11 6.1 0.2 4.6 4 1 1 5 5 5 0 Parkin co-regulated protein DUF2294 PF10057.9 KEG12679.1 - 0.097 12.8 0.2 8.2 6.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) Exonuc_VII_S PF02609.16 KEG12679.1 - 0.77 9.9 3.3 7.5 6.7 0.1 3.7 4 0 0 4 4 4 0 Exonuclease VII small subunit Ribosomal_L7Ae PF01248.26 KEG12680.1 - 7.9e-25 86.4 0.3 1.1e-24 86.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KEG12680.1 - 0.0017 18.2 0.4 0.01 15.7 0.0 2.2 2 1 1 3 3 3 1 PELOTA RNA binding domain Glyco_transf_15 PF01793.16 KEG12680.1 - 0.031 13.5 0.0 0.034 13.4 0.0 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF1512 PF07431.12 KEG12680.1 - 0.063 12.3 0.4 0.1 11.6 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1512) TetR_C_35 PF18556.1 KEG12681.1 - 0.015 15.4 1.3 0.015 15.4 1.3 3.6 3 0 0 3 3 3 0 Bacterial Tetracyclin repressor, C-terminal domain PXA PF02194.15 KEG12681.1 - 0.05 13.6 2.2 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 PXA domain Spc7_N PF15402.6 KEG12681.1 - 1.6 6.9 12.4 3.2 5.9 12.4 1.4 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Peptidase_S24 PF00717.23 KEG12683.1 - 7.6e-12 45.0 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Holin_9 PF16936.5 KEG12683.1 - 0.0058 16.8 2.7 0.0071 16.5 1.2 1.8 2 0 0 2 2 2 1 Putative holin Flavi_capsid PF01003.19 KEG12683.1 - 0.15 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C Clathrin PF00637.20 KEG12683.1 - 0.23 11.3 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS Rad60-SLD PF11976.8 KEG12684.1 - 4.8e-25 87.2 0.1 6.2e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEG12684.1 - 5.9e-12 45.2 0.0 7e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 KEG12684.1 - 0.091 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain SelP_N PF04592.14 KEG12685.1 - 0.29 10.5 5.8 0.41 10.0 5.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Com_YlbF PF06133.11 KEG12685.1 - 0.67 10.6 4.0 0.38 11.4 1.7 1.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA T3SS_needle_F PF09392.10 KEG12685.1 - 1.6 9.0 5.9 6.7 7.0 0.8 2.5 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF BSP_II PF05432.11 KEG12686.1 - 2.9e-05 23.9 3.9 3.9e-05 23.5 3.9 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 KEG12686.1 - 0.00054 20.0 4.5 0.00083 19.3 4.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region PAC1 PF16094.5 KEG12686.1 - 0.073 12.2 0.6 0.093 11.9 0.6 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Paf1 PF03985.13 KEG12686.1 - 0.2 10.6 7.3 0.29 10.1 7.3 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 KEG12686.1 - 0.2 9.9 3.0 0.26 9.5 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KEG12686.1 - 1.4 8.2 7.7 2.3 7.5 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein PTPRCAP PF15713.5 KEG12686.1 - 2.5 8.4 15.6 0.09 13.1 8.3 2.1 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 KEG12686.1 - 4.6 6.9 8.2 1.6 8.4 5.1 1.7 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 KEG12686.1 - 5 5.1 8.9 6.2 4.8 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 KEG12686.1 - 6.2 7.3 11.3 0.34 11.3 5.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pribosyltran_N PF13793.6 KEG12688.1 - 4e-23 81.6 0.2 4e-22 78.3 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEG12688.1 - 1.1e-22 81.0 1.0 3.3e-20 72.9 0.1 2.9 3 0 0 3 3 3 2 Phosphoribosyl synthetase-associated domain SPX PF03105.19 KEG12688.1 - 3.9e-06 27.0 19.8 0.00032 20.7 0.8 3.2 2 1 1 3 3 3 2 SPX domain Pribosyltran PF00156.27 KEG12688.1 - 0.023 14.2 0.2 0.7 9.4 0.1 3.0 3 0 0 3 3 3 0 Phosphoribosyl transferase domain DUF4477 PF14780.6 KEG12688.1 - 0.039 13.6 1.2 0.08 12.6 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Pkinase PF00069.25 KEG12689.1 - 2.5e-43 148.4 0.0 7.4e-43 146.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12689.1 - 4.2e-20 72.1 0.0 2.5e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kelch_1 PF01344.25 KEG12689.1 - 9.7e-05 21.9 0.5 0.055 13.1 0.1 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 KEG12689.1 - 0.0016 18.4 0.1 0.075 13.0 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG12689.1 - 0.01 16.1 1.1 0.37 11.2 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 KEG12689.1 - 0.065 13.2 5.6 0.067 13.2 0.1 3.1 4 0 0 4 4 4 0 Kelch motif Adeno_E3_CR2 PF02439.15 KEG12689.1 - 0.45 10.3 6.1 0.073 12.8 1.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 KEG12690.1 - 2e-37 129.0 0.0 5e-13 49.0 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12690.1 - 7.3e-19 68.1 0.0 1.6e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Kelch_1 PF01344.25 KEG12690.1 - 0.00026 20.5 2.6 0.012 15.2 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 KEG12690.1 - 0.023 15.0 0.0 5 7.5 0.0 3.1 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.6 KEG12690.1 - 0.032 14.2 0.5 23 5.1 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain APH PF01636.23 KEG12690.1 - 0.069 13.1 0.7 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.25 KEG12691.1 - 3.3e-38 131.9 0.1 1.1e-37 130.2 0.1 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KEG12691.1 - 1.6e-14 54.0 0.0 7.7e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 SPRY domain zf-RanBP PF00641.18 KEG12691.1 - 6.5e-05 22.2 1.6 6.5e-05 22.2 1.6 2.9 1 1 1 2 2 2 1 Zn-finger in Ran binding protein and others fn3 PF00041.21 KEG12692.1 - 1.1e-109 358.9 50.0 4.3e-05 23.8 0.2 40.1 38 6 0 38 38 38 25 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KEG12692.1 - 1.5e-45 153.7 49.3 0.0011 19.4 0.2 27.3 30 0 0 30 30 30 13 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KEG12692.1 - 7.4e-22 77.6 2.4 0.48 10.8 0.0 15.9 20 0 0 20 20 20 5 Interferon-alpha/beta receptor, fibronectin type III fn3_4 PF16794.5 KEG12692.1 - 6.6e-07 29.2 0.0 9.2 6.2 0.0 8.4 10 0 0 10 10 10 2 Fibronectin-III type domain DUF2369 PF10179.9 KEG12692.1 - 1.1e-06 29.0 12.2 2.4 8.6 0.0 11.0 15 0 0 15 15 15 2 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 KEG12692.1 - 0.0013 18.8 0.7 43 4.4 0.0 6.7 8 0 0 8 8 8 0 Fibronectin type III domain Arylsulfotran_N PF17425.2 KEG12692.1 - 0.0029 17.6 0.1 5.5 7.1 0.0 5.6 6 0 0 6 6 6 1 Arylsulfotransferase Ig-like domain zf-primase PF09329.11 KEG12693.1 - 1.2e-09 37.9 0.2 3.2e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.11 KEG12693.1 - 6.8e-07 29.0 7.4 6.8e-07 29.0 7.4 2.1 2 1 0 2 2 2 1 Mcm10 replication factor DUF3882 PF07066.11 KEG12693.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Lactococcus phage M3 protein BTB_2 PF02214.22 KEG12694.1 - 0.043 14.2 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Tim17 PF02466.19 KEG12695.1 - 4.6e-09 36.6 0.6 8e-09 35.9 0.6 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NADHdh PF00146.21 KEG12696.1 - 4.7e-08 32.7 11.5 5.6e-08 32.4 11.5 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Exo_endo_phos PF03372.23 KEG12697.1 - 1.4e-16 60.8 0.1 3.5e-16 59.4 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EVC2_like PF12297.8 KEG12698.1 - 0.25 10.0 0.4 0.31 9.7 0.4 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein JAB PF01398.21 KEG12699.1 - 2.8e-21 75.7 0.0 5.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KEG12699.1 - 0.0019 18.0 0.0 0.0054 16.5 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fe-S_biosyn PF01521.20 KEG12700.1 - 6.1e-11 42.5 0.1 3.4e-07 30.4 0.1 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis BILBO1_N PF18281.1 KEG12701.1 - 4.8e-15 55.8 0.0 1.3e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 BILBO1 N-terminal domain EF-hand_7 PF13499.6 KEG12701.1 - 7.2e-07 29.6 0.2 1.3e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG12701.1 - 0.0073 15.8 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KEG12701.1 - 0.026 14.5 0.1 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Spermine_synth PF01564.17 KEG12702.1 - 0.0054 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Mem_trans PF03547.18 KEG12703.1 - 3e-20 72.0 5.0 1.5e-09 36.8 0.0 3.3 3 1 0 3 3 3 3 Membrane transport protein PutA_N PF18083.1 KEG12704.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Proline utilization A N-terminal domain RskA PF10099.9 KEG12707.1 - 0.21 11.9 10.0 0.39 11.0 10.1 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CAP_N PF01213.19 KEG12707.1 - 1.3 8.5 4.1 1.9 7.9 4.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KEG12710.1 - 4 7.5 9.7 1.1 9.4 6.5 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 IBN_N PF03810.19 KEG12715.1 - 3.8e-05 23.5 0.9 0.0016 18.3 0.1 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 KEG12715.1 - 0.0055 17.2 12.9 0.0062 17.0 0.0 5.7 8 0 0 8 8 8 1 HEAT-like repeat Dicer_dimer PF03368.14 KEG12715.1 - 0.15 12.2 0.1 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 Dicer dimerisation domain RIX1 PF08167.12 KEG12715.1 - 0.31 10.8 3.4 1.1 9.0 0.0 3.3 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Peptidase_M41 PF01434.18 KEG12716.1 - 4.8e-59 199.4 0.1 8.3e-59 198.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEG12716.1 - 5.6e-42 143.3 0.0 1.6e-41 141.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG12716.1 - 6.9e-07 29.0 0.2 2.3e-06 27.3 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KEG12716.1 - 3.8e-06 26.9 0.0 2.3e-05 24.4 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG12716.1 - 1.5e-05 25.4 0.3 7.2e-05 23.2 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 KEG12716.1 - 4e-05 23.4 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG12716.1 - 4.4e-05 23.8 1.0 0.013 15.8 0.0 3.2 3 1 1 4 4 3 1 AAA domain NACHT PF05729.12 KEG12716.1 - 0.00046 20.1 0.2 0.012 15.5 0.0 2.7 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 KEG12716.1 - 0.00055 20.4 0.2 0.0066 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEG12716.1 - 0.00098 18.7 0.2 0.097 12.2 0.1 2.4 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KEG12716.1 - 0.0014 18.0 0.0 0.003 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 KEG12716.1 - 0.0024 17.8 0.0 0.0069 16.3 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 KEG12716.1 - 0.0024 17.9 0.0 0.0091 16.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KEG12716.1 - 0.0026 18.3 0.1 0.011 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEG12716.1 - 0.0029 17.4 0.0 0.0069 16.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEG12716.1 - 0.0034 16.8 0.2 0.007 15.8 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEG12716.1 - 0.0036 17.4 0.0 0.0089 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KEG12716.1 - 0.0098 16.0 0.0 0.036 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Dsl1_N PF11988.8 KEG12716.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal ABC_tran PF00005.27 KEG12716.1 - 0.014 15.9 0.4 0.088 13.3 0.0 2.3 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.22 KEG12716.1 - 0.015 15.7 0.0 0.053 13.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 KEG12716.1 - 0.035 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KEG12716.1 - 0.035 14.3 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEG12716.1 - 0.097 11.8 0.0 0.68 9.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KEG12716.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KEG12716.1 - 0.11 11.8 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KEG12716.1 - 0.14 11.5 0.6 1.3 8.3 0.0 2.7 4 0 0 4 4 4 0 KaiC Peptidase_M50B PF13398.6 KEG12716.1 - 0.23 11.0 0.1 0.37 10.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like U1snRNP70_N PF12220.8 KEG12717.1 - 0.0076 16.9 4.9 0.0076 16.9 4.9 3.8 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FKBP_C PF00254.28 KEG12718.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Thioredoxin PF00085.20 KEG12719.1 - 2.3e-18 66.1 0.0 2.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KEG12719.1 - 1.5e-05 24.5 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KEG12719.1 - 2.4e-05 24.8 0.1 0.00016 22.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KEG12719.1 - 0.00012 22.2 0.1 0.00017 21.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KEG12719.1 - 0.00013 21.9 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KEG12719.1 - 0.0002 21.6 0.1 0.037 14.4 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KEG12719.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 KEG12719.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Calsequestrin PF01216.17 KEG12719.1 - 0.037 13.1 0.0 0.049 12.7 0.0 1.2 1 1 0 1 1 1 0 Calsequestrin Pentapeptide PF00805.22 KEG12721.1 - 2.4e-09 36.6 10.6 0.00015 21.3 3.0 3.7 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KEG12721.1 - 1.8e-07 31.2 9.4 0.0086 16.2 1.7 3.5 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 KEG12721.1 - 2.2e-06 27.8 2.4 2.2e-06 27.8 2.4 2.8 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Xpo1 PF08389.12 KEG12722.1 - 0.11 12.5 0.0 0.82 9.7 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein 2-oxoacid_dh PF00198.23 KEG12724.1 - 9.6e-75 251.0 0.1 1.4e-74 250.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEG12724.1 - 1.4e-15 56.8 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEG12724.1 - 7.4e-12 45.4 0.3 1.9e-11 44.1 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain PA_decarbox PF05870.11 KEG12724.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Semialdhyde_dh PF01118.24 KEG12725.1 - 0.00016 22.1 0.0 0.00038 20.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEG12725.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEG12725.1 - 0.055 12.6 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GST_C_6 PF17171.4 KEG12725.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_11 PF08241.12 KEG12726.1 - 4.2e-14 52.9 0.1 3.7e-12 46.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG12726.1 - 1.2e-13 51.2 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG12726.1 - 2.4e-12 47.4 0.6 4e-10 40.3 0.2 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG12726.1 - 6.1e-07 30.1 0.1 3.3e-06 27.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG12726.1 - 3.9e-06 26.7 0.3 0.00011 22.1 0.3 2.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEG12726.1 - 0.0043 16.4 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KEG12726.1 - 0.016 14.2 0.0 0.2 10.5 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KEG12726.1 - 0.018 14.3 0.0 0.041 13.2 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEG12726.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TPR_2 PF07719.17 KEG12727.1 - 0.032 14.3 0.1 0.032 14.3 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 KEG12729.1 - 1.4e-20 72.9 0.1 2.9e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG12729.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltrn_RNA_4 PF09936.9 KEG12729.1 - 0.21 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase DUF4795 PF16043.5 KEG12730.1 - 3e-05 23.7 38.8 0.02 14.5 20.0 5.9 3 2 0 3 3 3 3 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 KEG12730.1 - 0.088 13.0 21.0 5.6 7.1 6.2 5.3 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family TLV_coat PF00429.19 KEG12730.1 - 0.11 11.2 0.2 0.3 9.7 0.2 1.7 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Ribosomal_S15 PF00312.22 KEG12730.1 - 0.26 11.5 2.7 45 4.4 0.0 4.1 4 0 0 4 4 4 0 Ribosomal protein S15 hDGE_amylase PF14701.6 KEG12730.1 - 0.41 9.7 2.6 0.83 8.7 2.6 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF1759 PF03564.15 KEG12730.1 - 1.3 9.0 7.2 2.1 8.3 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1759) DUF4988 PF16378.5 KEG12730.1 - 1.6 8.3 5.6 38 3.9 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function Atg14 PF10186.9 KEG12730.1 - 2.1 7.4 23.3 0.29 10.2 0.1 3.5 3 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAMP PF00672.25 KEG12730.1 - 2.8 8.4 7.2 2.9 8.3 0.1 4.3 5 0 0 5 5 5 0 HAMP domain Cob_adeno_trans PF01923.18 KEG12730.1 - 3.2 7.9 8.6 6.2 6.9 0.1 3.9 2 2 0 2 2 2 0 Cobalamin adenosyltransferase NIF PF03031.18 KEG12731.1 - 1.7e-11 44.1 0.0 2.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PSS PF03034.15 KEG12732.1 - 2.6e-92 309.4 7.4 4.8e-92 308.6 7.4 1.4 1 0 0 1 1 1 1 Phosphatidyl serine synthase Carb_kinase PF01256.17 KEG12733.1 - 1e-53 182.3 12.4 5.4e-53 180.0 5.5 3.0 2 1 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 KEG12733.1 - 7e-47 159.5 1.6 9.2e-47 159.1 0.4 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus Phos_pyr_kin PF08543.12 KEG12733.1 - 0.081 12.3 0.0 0.081 12.3 0.0 2.7 3 0 0 3 3 3 0 Phosphomethylpyrimidine kinase PAP_central PF04928.17 KEG12734.1 - 5.8e-59 199.1 0.0 1e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KEG12734.1 - 9.4e-30 103.5 0.0 1.8e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KEG12734.1 - 1.6e-06 28.3 0.0 3.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 KEG12734.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm DUF2204 PF09970.9 KEG12734.1 - 0.042 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) FYVE PF01363.21 KEG12735.1 - 6.1e-15 55.1 20.9 6.1e-15 55.1 20.9 2.8 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.22 KEG12735.1 - 4.7e-13 49.0 0.0 8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG12735.1 - 5.2e-12 46.0 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KEG12735.1 - 6.3e-05 23.3 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain F-box-like PF12937.7 KEG12735.1 - 0.00024 20.9 0.4 0.0011 18.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like AAA_16 PF13191.6 KEG12735.1 - 0.00086 19.7 0.1 0.0023 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEG12735.1 - 0.0023 17.9 0.2 0.0072 16.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Arf PF00025.21 KEG12735.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KEG12735.1 - 0.036 13.6 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KEG12735.1 - 0.056 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KEG12735.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 KEG12735.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEG12735.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pro_racemase PF05544.11 KEG12737.1 - 6.3e-124 413.2 0.1 7.1e-124 413.1 0.1 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 KEG12737.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HTH_20 PF12840.7 KEG12737.1 - 0.087 12.9 0.4 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain CSD PF00313.22 KEG12738.1 - 8.2e-12 44.8 0.3 1.2e-05 25.1 0.1 4.1 4 0 0 4 4 4 3 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KEG12738.1 - 0.012 15.2 0.4 2.2 8.0 0.2 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain WD40 PF00400.32 KEG12739.1 - 0.00017 22.3 16.0 0.13 13.1 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG12739.1 - 0.001 19.3 0.0 0.085 13.2 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.23 KEG12740.1 - 8.2e-104 347.1 0.0 2.2e-103 345.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG12740.1 - 1.5e-19 70.4 0.0 5.3e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding CENP-F_leu_zip PF10473.9 KEG12740.1 - 0.0031 17.5 11.1 0.0031 17.5 11.1 6.7 2 2 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KEG12740.1 - 0.012 15.9 16.8 0.012 15.9 16.8 6.2 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KEG12740.1 - 0.079 12.3 95.3 0.018 14.4 3.3 5.7 3 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding Ras PF00071.22 KEG12741.1 - 1.3e-23 83.4 0.0 2.3e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG12741.1 - 1.7e-10 41.2 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG12741.1 - 0.00016 21.1 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KEG12741.1 - 0.0025 18.2 2.3 0.0073 16.7 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KEG12741.1 - 0.01 15.9 0.1 0.027 14.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KEG12741.1 - 0.018 15.0 0.4 0.045 13.7 0.2 1.7 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 KEG12741.1 - 0.02 14.1 0.3 0.08 12.1 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KEG12741.1 - 0.031 13.6 0.1 0.088 12.2 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KEG12741.1 - 0.063 13.2 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KEG12741.1 - 0.16 12.5 1.6 0.68 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 KEG12741.1 - 0.31 11.3 2.0 0.32 11.3 0.2 2.0 2 1 0 2 2 2 0 AAA domain Phostensin_N PF13916.6 KEG12742.1 - 0.69 10.3 0.0 0.69 10.3 0.0 3.3 3 1 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal DEAD PF00270.29 KEG12743.1 - 5.7e-41 140.2 0.0 1.1e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG12743.1 - 3.4e-23 82.1 0.0 1.6e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEG12743.1 - 3.1e-14 52.9 0.1 6.1e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Nt_Gln_amidase PF09764.9 KEG12744.1 - 4.3e-53 179.7 0.0 4.9e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Tautomerase_2 PF14552.6 KEG12744.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme DEAD PF00270.29 KEG12745.1 - 1e-46 158.9 0.1 4.6e-46 156.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG12745.1 - 1.3e-27 96.3 0.0 1.5e-26 92.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KEG12745.1 - 6.9e-06 25.4 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEG12745.1 - 8.9e-06 25.8 0.0 5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_S5_C PF03719.15 KEG12746.1 - 2.5e-10 39.7 0.2 3.9e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KEG12746.1 - 1.8e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1918 PF08940.11 KEG12746.1 - 0.14 11.8 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Vault PF01505.18 KEG12747.1 - 1.5e-42 143.5 4.2 4.7e-13 49.1 0.1 4.9 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 KEG12747.1 - 4.2e-42 142.9 0.0 7e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_4 PF17796.1 KEG12747.1 - 2.9e-18 65.7 0.9 5.7e-17 61.5 0.0 3.3 3 0 0 3 3 3 1 Major Vault Protein repeat domain Vault_2 PF17794.1 KEG12747.1 - 1.5e-16 60.5 0.5 7.5e-14 51.9 0.2 2.9 2 1 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 KEG12747.1 - 2.8e-16 59.3 0.1 6.3e-14 51.8 0.0 3.7 3 1 0 3 3 3 1 Major Vault Protein Repeat domain CBF PF03914.17 KEG12748.1 - 5.7e-31 107.8 4.7 1.1e-30 106.9 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 KEG12748.1 - 8.3e-06 26.2 0.1 8.3e-06 26.2 0.1 2.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein DUF4680 PF15730.5 KEG12748.1 - 0.19 12.1 2.3 0.27 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) DUF2894 PF11445.8 KEG12748.1 - 1.4 9.3 7.5 0.79 10.2 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) TSNAXIP1_N PF15739.5 KEG12748.1 - 4.3 7.8 10.6 0.87 10.0 0.4 3.1 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF1943 PF09172.11 KEG12750.1 - 0.047 12.9 1.7 0.15 11.3 1.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SCIMP PF15050.6 KEG12750.1 - 1.5 9.3 5.0 6.6 7.2 5.0 2.1 1 0 0 1 1 1 0 SCIMP protein DUF4407 PF14362.6 KEG12750.1 - 6.5 6.0 14.0 18 4.5 14.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LCD1 PF09798.9 KEG12750.1 - 7.5 4.9 13.1 12 4.3 8.8 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein GAS PF13851.6 KEG12752.1 - 9.4e-59 198.1 26.9 9.4e-59 198.1 26.9 3.0 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KEG12752.1 - 4.3e-05 22.5 18.7 4.3e-05 22.5 18.7 3.9 1 1 2 3 3 3 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KEG12752.1 - 0.95 9.5 57.8 0.16 12.0 14.8 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SET PF00856.28 KEG12753.1 - 3.7e-05 24.2 0.0 0.00058 20.3 0.0 2.7 1 1 0 1 1 1 1 SET domain HypA PF01155.19 KEG12753.1 - 4.2 7.4 10.5 2.5 8.2 7.4 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SNF2_N PF00176.23 KEG12757.1 - 4.8e-28 97.9 0.0 9.6e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.7 KEG12757.1 - 2e-26 93.1 0.3 2.4e-20 73.2 0.0 2.5 2 1 1 3 3 3 2 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.31 KEG12757.1 - 1.1e-15 58.0 0.1 2.2e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG12757.1 - 1.4e-09 38.2 0.0 4.7e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG12757.1 - 1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KEG12757.1 - 0.0023 17.2 0.0 0.0045 16.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SF-assemblin PF06705.11 KEG12758.1 - 1.3e-12 47.7 11.4 1.7e-12 47.2 11.4 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF1515 PF07439.11 KEG12758.1 - 0.27 11.3 5.2 2.1 8.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) OmpH PF03938.14 KEG12758.1 - 8.6 6.7 11.6 3.5 8.0 8.5 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) cNMP_binding PF00027.29 KEG12759.1 - 1.7e-07 31.2 0.1 0.053 13.6 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Arf PF00025.21 KEG12760.1 - 4.2e-06 26.3 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Herpes_IE2_3 PF03361.14 KEG12760.1 - 0.006 16.5 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Herpes virus intermediate/early protein 2/3 G-alpha PF00503.20 KEG12760.1 - 0.0093 15.2 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 KEG12760.1 - 0.048 14.1 0.0 0.057 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KEG12760.1 - 0.14 11.9 0.0 14 5.4 0.0 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_PrkA PF08298.11 KEG12760.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain LRR_4 PF12799.7 KEG12762.1 - 1.4e-15 57.1 6.4 0.055 13.9 0.1 6.5 2 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG12762.1 - 5.7e-10 38.4 16.8 0.017 15.1 0.4 8.7 10 0 0 10 10 10 3 Leucine Rich repeat LRR_8 PF13855.6 KEG12762.1 - 8.8e-09 35.0 5.7 0.23 11.3 0.3 5.5 4 1 3 7 7 7 5 Leucine rich repeat LRR_1 PF00560.33 KEG12762.1 - 6.9e-06 25.9 14.5 17 6.5 0.6 8.7 7 2 0 7 7 7 2 Leucine Rich Repeat DnaJ PF00226.31 KEG12764.1 - 8.1e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.31 KEG12765.1 - 2e-07 31.1 0.2 6.9e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain ABG_transport PF03806.13 KEG12765.1 - 0.15 10.3 0.1 0.28 9.4 0.1 1.3 1 0 0 1 1 1 0 AbgT putative transporter family Sigma70_ner PF04546.13 KEG12765.1 - 0.5 10.2 17.6 0.12 12.3 1.7 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region DnaJ PF00226.31 KEG12766.1 - 3e-14 52.9 0.3 5.8e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain RNA_pol_Rbc25 PF08292.12 KEG12766.1 - 0.019 15.2 1.6 0.064 13.5 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Gly_kinase PF02595.15 KEG12766.1 - 0.14 11.1 0.3 0.26 10.3 0.1 1.5 2 0 0 2 2 2 0 Glycerate kinase family Nuc_deoxyrib_tr PF05014.15 KEG12766.1 - 0.25 11.4 2.2 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Formin_GBD_N PF18382.1 KEG12767.1 - 0.063 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain Stathmin PF00836.19 KEG12767.1 - 5.1 7.1 10.9 2.8 7.9 1.3 2.9 2 1 1 3 3 3 0 Stathmin family IU_nuc_hydro PF01156.19 KEG12769.1 - 3.4e-69 233.7 0.0 4e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CAP59_mtransfer PF11735.8 KEG12769.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MOZ_SAS PF01853.18 KEG12770.1 - 5.3e-62 208.7 0.0 8.9e-62 207.9 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEG12770.1 - 1e-09 37.8 0.1 3.8e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 KEG12770.1 - 3e-09 36.6 0.1 6.9e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KEG12770.1 - 0.0039 17.6 0.0 0.009 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEG12770.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4823 PF16105.5 KEG12770.1 - 0.14 12.0 0.7 26 4.7 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4823) SDA1 PF05285.12 KEG12771.1 - 4.4e-14 52.7 24.7 4.9e-14 52.5 24.7 1.0 1 0 0 1 1 1 1 SDA1 Ureide_permease PF07168.11 KEG12771.1 - 0.98 8.1 2.3 1.2 7.8 2.3 1.2 1 0 0 1 1 1 0 Ureide permease IQ PF00612.27 KEG12773.1 - 3.6e-08 32.5 45.6 0.029 14.2 0.2 9.3 9 0 0 9 9 9 7 IQ calmodulin-binding motif Inositol_P PF00459.25 KEG12774.1 - 5.1e-63 213.1 0.1 6.2e-63 212.8 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.9 KEG12775.1 - 2.4e-64 217.1 0.1 2.7e-64 217.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KEG12775.1 - 1.4e-06 28.8 0.2 0.0002 21.9 0.0 2.2 1 1 1 2 2 2 2 OTU-like cysteine protease FAM76 PF16046.5 KEG12776.1 - 1.4 8.2 12.6 28 3.9 0.0 2.8 2 0 0 2 2 2 0 FAM76 protein FIVAR PF07554.13 KEG12776.1 - 1.6 9.5 6.6 16 6.4 0.3 3.2 2 1 0 2 2 2 0 FIVAR domain UVR PF02151.19 KEG12776.1 - 1.7 8.5 25.2 0.76 9.6 3.3 5.4 4 0 0 4 4 4 0 UvrB/uvrC motif Nas2_N PF18265.1 KEG12776.1 - 2.4 8.1 5.8 21 5.1 0.7 3.6 2 0 0 2 2 2 0 Nas2 N_terminal domain Abhydrolase_6 PF12697.7 KEG12777.1 - 0.00031 21.4 0.2 0.00031 21.4 0.2 2.7 3 2 1 4 4 4 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KEG12777.1 - 0.00037 20.4 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KEG12777.1 - 0.03 13.9 0.4 0.32 10.5 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 KEG12777.1 - 0.035 13.9 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KEG12777.1 - 0.083 12.6 0.7 0.17 11.6 0.7 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KEG12777.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2685 PF10886.8 KEG12777.1 - 0.22 11.7 0.4 0.53 10.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) DUF5480 PF17576.2 KEG12777.1 - 7 6.7 8.0 21 5.2 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5480) zf-ZPR1 PF03367.13 KEG12778.1 - 3.3e-112 371.6 0.1 9.3e-56 188.1 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KEG12778.1 - 2.9e-05 24.1 1.4 0.068 13.2 0.1 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KEG12778.1 - 0.00052 20.1 6.9 2.7 8.2 0.0 4.4 4 0 0 4 4 4 1 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.19 KEG12778.1 - 0.003 17.9 4.5 1 9.7 0.5 2.4 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 KEG12778.1 - 0.0062 16.5 2.9 4.1 7.4 1.3 3.7 4 1 0 4 4 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KEG12778.1 - 0.011 15.7 1.4 3 7.9 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbons DiS_P_DiS PF06750.13 KEG12778.1 - 0.032 14.4 1.4 27 5.0 1.2 3.1 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-ribbon_3 PF13248.6 KEG12778.1 - 0.045 13.2 13.5 3.9 7.0 0.0 4.3 4 0 0 4 4 4 0 zinc-ribbon domain NLE PF08154.12 KEG12778.1 - 0.076 13.6 0.2 11 6.7 0.0 3.2 3 0 0 3 3 3 0 NLE (NUC135) domain Zn_Tnp_IS1595 PF12760.7 KEG12778.1 - 0.092 12.7 9.9 4.2 7.4 0.4 3.4 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 KEG12778.1 - 0.32 11.4 10.8 2.7 8.5 0.4 3.3 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-ISL3 PF14690.6 KEG12778.1 - 0.42 11.3 8.1 14 6.5 0.1 4.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-Di19 PF05605.12 KEG12778.1 - 0.43 10.9 6.2 2.2 8.6 0.1 3.8 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 KEG12778.1 - 0.71 9.8 7.8 3.6 7.6 0.1 3.6 3 1 1 4 4 4 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.9 KEG12778.1 - 0.79 9.2 3.6 2 7.9 0.2 2.8 1 1 1 2 2 2 0 Mu-like prophage protein Com Cys_rich_CPXG PF14255.6 KEG12778.1 - 1.2 9.1 8.7 3.9 7.4 0.3 4.0 4 0 0 4 4 4 0 Cysteine-rich CPXCG zf-Mss51 PF13824.6 KEG12778.1 - 1.2 9.3 7.8 39 4.4 0.1 4.2 5 0 0 5 5 4 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_CopZ PF18423.1 KEG12778.1 - 1.4 8.9 9.1 28 4.8 0.1 4.2 4 0 0 4 4 4 0 Zinc binding domain zf-RING_4 PF14570.6 KEG12778.1 - 1.4 8.7 4.4 12 5.8 0.1 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_7 PF02591.15 KEG12778.1 - 2.2 8.5 5.0 1.1e+02 3.0 0.1 3.8 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-AN1 PF01428.16 KEG12778.1 - 3.6 7.8 8.2 23 5.2 0.1 3.8 4 0 0 4 4 4 0 AN1-like Zinc finger zf-LITAF-like PF10601.9 KEG12778.1 - 5.2 7.4 8.6 26 5.2 0.0 3.4 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain DZR PF12773.7 KEG12778.1 - 5.2 7.2 11.5 18 5.5 1.9 3.6 2 2 1 3 3 3 0 Double zinc ribbon Cys_rich_KTR PF14205.6 KEG12778.1 - 5.4 6.9 9.5 0.61 9.9 0.1 3.3 3 1 0 3 3 3 0 Cysteine-rich KTR CpXC PF14353.6 KEG12778.1 - 6.2 6.9 11.9 72 3.5 2.6 4.3 2 2 1 3 3 3 0 CpXC protein zinc_ribbon_10 PF10058.9 KEG12778.1 - 8.3 6.2 7.9 16 5.3 0.1 3.4 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 KEG12778.1 - 9 6.3 12.3 21 5.1 2.3 4.1 3 1 0 3 3 3 0 zinc-ribbon domain ACTH_assoc PF16102.5 KEG12779.1 - 0.014 16.2 2.5 0.037 14.8 2.5 1.8 1 0 0 1 1 1 0 ACTH-associated domain Cytochrom_C552 PF02335.15 KEG12779.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c552 Fez1 PF06818.15 KEG12780.1 - 0.0068 16.9 24.3 0.1 13.1 6.4 2.1 1 1 1 2 2 2 2 Fez1 DUF4200 PF13863.6 KEG12780.1 - 0.0091 16.4 3.7 0.0091 16.4 3.7 3.4 1 1 1 3 3 3 1 Domain of unknown function (DUF4200) HMMR_N PF15905.5 KEG12780.1 - 0.27 10.7 19.7 0.44 10.0 19.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Phage_GPO PF05929.11 KEG12780.1 - 0.52 9.9 7.9 0.73 9.4 7.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF16 PF01519.16 KEG12780.1 - 0.53 10.8 7.0 0.34 11.4 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FapA PF03961.13 KEG12780.1 - 1.4 7.5 9.5 2.2 6.8 9.2 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Ly49 PF08391.10 KEG12780.1 - 2 8.8 7.4 0.26 11.7 1.7 2.3 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region Ion_trans PF00520.31 KEG12782.1 - 3e-109 364.0 72.0 2.2e-30 105.7 10.0 4.2 4 0 0 4 4 4 4 Ion transport protein RabGAP-TBC PF00566.18 KEG12783.1 - 6.9e-18 65.1 2.2 6.9e-18 65.1 2.2 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Abhydrolase_6 PF12697.7 KEG12784.1 - 1.2e-06 29.3 0.0 1.8e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEG12784.1 - 5.8e-06 25.7 0.0 1e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG12784.1 - 1.8e-05 24.5 0.0 0.00033 20.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_L36e PF01158.18 KEG12786.1 - 3.2e-29 101.0 5.7 3.7e-29 100.8 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.12 KEG12787.1 - 2.4e-15 56.3 0.5 2.9e-15 56.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ATP-synt_C PF00137.21 KEG12788.1 - 2.9e-09 37.2 11.8 5.3e-09 36.3 11.8 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Qn_am_d_aIV PF09100.10 KEG12789.1 - 0.12 12.2 0.0 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV PCI PF01399.27 KEG12790.1 - 7.5e-12 45.7 0.4 2.3e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KEG12790.1 - 0.0017 18.4 0.8 0.0017 18.4 0.8 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN5 C-terminal domain Vps39_1 PF10366.9 KEG12790.1 - 0.014 15.7 0.5 0.35 11.2 0.1 2.6 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 MAGE_N PF12440.8 KEG12792.1 - 0.0039 17.8 8.8 0.0048 17.5 8.8 1.2 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal DUF4718 PF15842.5 KEG12792.1 - 0.0069 16.2 1.7 0.0087 15.9 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4718) DUF5587 PF17825.1 KEG12792.1 - 0.2 8.9 0.9 0.22 8.8 0.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) CAP_N PF01213.19 KEG12792.1 - 0.32 10.4 7.6 0.39 10.2 7.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KEG12792.1 - 0.37 10.8 6.3 0.47 10.5 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator LIN37 PF15306.6 KEG12792.1 - 2.1 8.5 7.2 1.6 9.0 6.2 1.4 1 1 1 2 2 2 0 LIN37 TMEM171 PF15471.6 KEG12792.1 - 2.5 7.0 7.4 3.5 6.5 7.4 1.3 1 1 0 1 1 1 0 Transmembrane protein family 171 Rrn6 PF10214.9 KEG12792.1 - 3.2 6.1 8.0 3.6 5.9 8.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3818 PF12825.7 KEG12793.1 - 0.15 11.1 0.4 0.28 10.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Ras PF00071.22 KEG12794.1 - 1.1e-50 171.4 0.0 1.4e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG12794.1 - 1.8e-34 118.6 0.0 2.7e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG12794.1 - 5.5e-10 39.0 0.0 7.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEG12794.1 - 1.7e-07 30.9 0.1 6.4e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEG12794.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KEG12794.1 - 0.0003 20.7 0.3 0.12 12.3 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KEG12794.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KEG12794.1 - 0.047 13.4 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KEG12794.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KEG12794.1 - 0.14 12.5 0.2 0.34 11.3 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Pex24p PF06398.11 KEG12795.1 - 0.052 12.5 0.6 0.086 11.8 0.6 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CNOT1_CAF1_bind PF16415.5 KEG12796.1 - 5.1e-76 255.0 1.0 1e-75 254.0 1.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 KEG12796.1 - 1.1e-39 135.6 0.0 1.1e-39 135.6 0.0 4.1 3 1 1 4 4 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KEG12796.1 - 2.5e-23 82.7 4.4 2.5e-23 82.7 4.4 3.5 3 0 0 3 3 1 1 Domain of unknown function (DUF3819) TFIIA PF03153.13 KEG12796.1 - 1.2e-05 25.5 70.6 0.0028 17.7 30.5 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 KEG12796.1 - 0.00031 21.0 21.0 0.031 14.4 3.6 3.2 3 0 0 3 3 3 2 DDHD domain Pex14_N PF04695.13 KEG12796.1 - 0.0038 17.9 16.4 0.0038 17.9 16.4 4.3 4 1 0 5 5 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 KEG12796.1 - 0.022 14.2 27.2 0.4 10.1 8.8 2.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 KEG12796.1 - 0.038 14.0 40.8 0.44 10.5 15.2 3.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) SET PF00856.28 KEG12796.1 - 0.12 12.8 4.6 0.85 10.0 0.4 3.2 3 0 0 3 3 3 0 SET domain PAT1 PF09770.9 KEG12796.1 - 0.15 10.3 57.5 0.14 10.4 24.3 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 TT_ORF1 PF02956.14 KEG12796.1 - 0.16 10.6 12.7 0.44 9.2 3.1 2.2 2 0 0 2 2 2 0 TT viral orf 1 Velvet PF11754.8 KEG12796.1 - 0.35 10.8 32.1 0.2 11.6 10.2 2.7 3 0 0 3 3 3 0 Velvet factor EPL1 PF10513.9 KEG12796.1 - 0.47 10.8 37.5 0.55 10.6 12.7 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like ABC2_membrane_2 PF12679.7 KEG12796.1 - 0.85 8.9 9.6 1 8.6 1.3 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein CTNNB1_binding PF08347.11 KEG12796.1 - 1.2 9.3 21.6 3 8.0 4.9 2.7 2 0 0 2 2 2 0 N-terminal CTNNB1 binding SID-1_RNA_chan PF13965.6 KEG12796.1 - 1.3 7.4 9.5 2.8 6.3 1.1 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 GREB1 PF15782.5 KEG12796.1 - 1.5 5.9 31.4 0.46 7.5 11.8 2.2 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer CNDH2_C PF16858.5 KEG12796.1 - 1.9 8.3 29.6 0.43 10.4 6.7 3.3 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF913 PF06025.12 KEG12796.1 - 2.8 6.8 22.2 0.064 12.2 0.9 3.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.15 KEG12796.1 - 3.3 7.2 45.4 0.35 10.4 17.7 3.1 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist NARP1 PF12569.8 KEG12796.1 - 3.9 6.3 32.0 6.4 5.6 11.0 2.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.12 KEG12796.1 - 4.5 7.5 29.8 2.6 8.2 6.0 3.0 3 0 0 3 3 3 0 GAGA binding protein-like family DUF4471 PF14740.6 KEG12796.1 - 4.7 6.4 16.1 6 6.0 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Otopetrin PF03189.13 KEG12796.1 - 5 5.8 15.8 3.9 6.2 4.6 2.3 2 0 0 2 2 2 0 Otopetrin Zip PF02535.22 KEG12796.1 - 6.5 5.9 17.5 3.2 6.9 1.4 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Pkinase_fungal PF17667.1 KEG12796.1 - 7.6 5.2 18.7 3.4 6.4 5.6 2.4 2 0 0 2 2 2 0 Fungal protein kinase Neur_chan_memb PF02932.16 KEG12796.1 - 7.9 6.5 29.7 1.6 8.7 6.9 2.9 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4746 PF15928.5 KEG12796.1 - 8 5.8 26.8 1.3 8.4 4.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) UPF0565 PF10561.9 KEG12796.1 - 9.5 5.3 14.2 11 5.1 4.5 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 SOG2 PF10428.9 KEG12796.1 - 9.8 5.2 35.7 0.022 14.0 4.9 2.7 3 0 0 3 3 3 0 RAM signalling pathway protein Not1 PF04054.15 KEG12797.1 - 1e-95 320.8 2.5 2.2e-95 319.7 2.5 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 SUIM_assoc PF16619.5 KEG12797.1 - 0.0017 18.3 13.4 0.0058 16.7 7.4 2.7 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 MarR PF01047.22 KEG12797.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 MarR family Folliculin PF11704.8 KEG12797.1 - 0.16 11.9 2.6 0.17 11.8 1.0 1.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4834 PF16118.5 KEG12797.1 - 0.25 12.3 4.6 0.73 10.8 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2203 PF09969.9 KEG12797.1 - 1.7 9.3 7.1 2.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2722 PF10846.8 KEG12797.1 - 2 7.2 13.4 3.7 6.4 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 KEG12797.1 - 5.4 6.5 21.3 4.4 6.8 17.5 2.3 2 0 0 2 2 2 0 Spt20 family PHF5 PF03660.14 KEG12798.1 - 1.3e-33 115.3 11.0 1.6e-33 115.0 11.0 1.0 1 0 0 1 1 1 1 PHF5-like protein zf-CHY PF05495.12 KEG12798.1 - 5.5 7.5 13.7 44 4.7 13.7 2.1 1 1 0 1 1 1 0 CHY zinc finger zf-RING_2 PF13639.6 KEG12799.1 - 5.3e-11 42.7 10.2 1e-10 41.8 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEG12799.1 - 1.4e-08 34.9 6.6 2.9e-08 33.9 6.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEG12799.1 - 3.5e-08 33.0 4.7 8.2e-08 31.9 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEG12799.1 - 6.1e-08 32.4 9.5 1.2e-07 31.5 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG12799.1 - 1e-05 25.5 2.9 2.3e-05 24.4 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KEG12799.1 - 8.3e-05 22.4 8.8 0.00015 21.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG12799.1 - 0.00019 21.3 9.7 0.00031 20.6 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEG12799.1 - 0.00044 20.1 10.2 0.00075 19.3 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG12799.1 - 0.0016 18.4 8.4 0.0033 17.4 8.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KEG12799.1 - 0.0052 16.4 8.2 0.013 15.1 8.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KEG12799.1 - 0.1 12.8 5.9 0.42 10.8 5.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.12 KEG12799.1 - 0.23 10.8 0.5 0.38 10.1 0.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CxC4 PF18717.1 KEG12799.1 - 0.64 9.9 4.4 1.7 8.5 3.1 2.1 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases zf-C3HC4_4 PF15227.6 KEG12799.1 - 0.77 10.0 5.5 0.88 9.8 3.6 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KEG12799.1 - 2.9 8.3 9.5 4.8 7.6 9.5 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 KEG12799.1 - 2.9 7.8 9.4 5.7 6.9 9.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CusF_Ec PF11604.8 KEG12800.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF ENTH PF01417.20 KEG12801.1 - 7.2e-08 32.5 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 KEG12801.1 - 0.00018 20.6 0.0 0.11 11.4 0.0 2.7 2 1 0 2 2 2 2 ANTH domain PRTase_2 PF15609.6 KEG12801.1 - 0.01 15.4 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase ATP-grasp_2 PF08442.10 KEG12802.1 - 6.7e-63 211.9 0.9 1.2e-62 211.1 0.9 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KEG12802.1 - 2.8e-24 85.7 0.5 1.5e-23 83.3 0.1 2.2 2 0 0 2 2 2 1 CoA-ligase GARS_A PF01071.19 KEG12802.1 - 0.0068 16.2 0.9 0.029 14.2 0.9 2.1 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Bromodomain PF00439.25 KEG12806.1 - 2.5e-19 69.1 0.0 3.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Exonuc_VII_S PF02609.16 KEG12806.1 - 0.055 13.5 4.7 0.066 13.3 3.4 1.8 1 1 1 2 2 2 0 Exonuclease VII small subunit TFIIA PF03153.13 KEG12806.1 - 0.63 10.0 28.2 0.72 9.8 28.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KEG12806.1 - 2 7.6 27.7 2.5 7.3 27.7 1.2 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 KEG12806.1 - 9.6 5.5 13.7 13 5.1 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2076 PF09849.9 KEG12806.1 - 9.6 6.2 23.6 16 5.5 23.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) GTP1_OBG PF01018.22 KEG12807.1 - 1.5e-41 141.6 4.7 2.1e-41 141.1 4.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KEG12807.1 - 8.6e-19 67.7 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG12807.1 - 1.7e-06 27.6 0.0 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KEG12807.1 - 0.036 13.5 0.0 0.31 10.5 0.0 2.3 2 1 0 2 2 2 0 ADP-ribosylation factor family DSHCT PF08148.12 KEG12808.1 - 7.1e-46 155.9 2.0 1.1e-45 155.3 0.4 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KEG12808.1 - 6.3e-44 150.9 0.1 2.9e-43 148.8 0.0 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 KEG12808.1 - 5.3e-22 78.4 0.5 5.2e-21 75.2 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG12808.1 - 2.8e-07 30.7 0.0 5.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEG12808.1 - 5.5e-07 29.9 0.0 4.3e-06 27.0 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEG12808.1 - 0.0052 17.1 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KEG12808.1 - 0.0054 16.7 0.7 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea PhoH PF02562.16 KEG12808.1 - 0.019 14.4 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 KEG12808.1 - 0.029 13.4 0.0 0.074 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FlxA PF14282.6 KEG12808.1 - 0.041 13.9 2.0 0.088 12.8 0.9 2.0 2 0 0 2 2 2 0 FlxA-like protein CobA_CobO_BtuR PF02572.15 KEG12808.1 - 0.096 12.9 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DnaB_C PF03796.15 KEG12808.1 - 0.11 11.8 0.1 0.41 10.0 0.1 1.9 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Cep57_MT_bd PF06657.13 KEG12808.1 - 1.7 9.1 7.6 5.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 RNase_PH PF01138.21 KEG12809.1 - 3.8e-27 95.4 1.3 5.9e-27 94.8 1.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEG12809.1 - 0.053 13.6 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fer4_11 PF13247.6 KEG12809.1 - 0.21 11.7 2.9 1.5 9.0 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Adap_comp_sub PF00928.21 KEG12810.1 - 5.4e-51 173.5 0.0 6.8e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEG12810.1 - 0.00027 20.9 0.9 0.00061 19.7 0.9 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 KEG12811.1 - 2e-09 37.1 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG12811.1 - 0.00067 19.3 0.0 0.00073 19.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peroxin-22 PF12827.7 KEG12812.1 - 0.032 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Cullin PF00888.22 KEG12813.1 - 1.5e-83 281.5 1.9 1.8e-83 281.2 1.9 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEG12813.1 - 3.3e-12 46.2 0.0 1.7e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain LexA_DNA_bind PF01726.16 KEG12813.1 - 0.054 13.3 0.0 11 5.8 0.0 3.3 2 1 0 2 2 2 0 LexA DNA binding domain TrmB PF01978.19 KEG12813.1 - 0.057 13.3 0.0 8.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 KEG12813.1 - 0.079 13.0 1.3 0.16 12.0 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PHP PF02811.19 KEG12813.1 - 0.16 12.3 0.0 0.41 10.9 0.0 1.9 1 1 0 1 1 1 0 PHP domain Fibrillarin PF01269.17 KEG12814.1 - 1.1e-102 341.9 0.0 1.3e-102 341.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KEG12814.1 - 3.9e-05 23.4 0.0 6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KEG12814.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KEG12814.1 - 0.14 11.8 0.0 0.55 9.8 0.0 1.8 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F ECSIT PF06239.11 KEG12816.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway NRDD PF13597.6 KEG12816.1 - 2.4 6.8 7.7 2.3 6.9 7.7 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase RabGAP-TBC PF00566.18 KEG12817.1 - 1.7e-07 31.1 1.5 4.4e-07 29.8 1.5 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CH PF00307.31 KEG12818.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KEG12818.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain PIG-P PF08510.12 KEG12819.1 - 9.3e-28 96.6 2.9 1.1e-27 96.4 2.9 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KEG12819.1 - 0.0029 17.9 8.5 0.0044 17.3 8.5 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Choline_transpo PF04515.12 KEG12819.1 - 0.021 14.0 2.3 0.026 13.7 2.3 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter HPS3_N PF14761.6 KEG12820.1 - 0.014 14.9 0.7 0.023 14.2 0.7 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 GBR2_CC PF18455.1 KEG12820.1 - 0.063 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF2533 PF10752.9 KEG12820.1 - 0.47 10.9 2.1 28 5.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2533) Cep57_CLD PF14073.6 KEG12820.1 - 1.7 8.6 4.6 0.49 10.4 1.4 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 FAST_1 PF06743.15 KEG12821.1 - 0.0003 20.7 0.0 1.2 9.1 0.0 4.7 3 2 3 6 6 6 2 FAST kinase-like protein, subdomain 1 DUF1749 PF08538.10 KEG12822.1 - 2e-12 46.8 0.0 3.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 KEG12822.1 - 0.00099 18.4 0.0 0.011 15.0 0.0 2.4 3 1 0 3 3 3 1 Serine aminopeptidase, S33 DUF3007 PF11460.8 KEG12823.1 - 0.2 11.9 1.0 5.1 7.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) MRP-S32 PF10210.9 KEG12823.1 - 3.4 8.3 10.2 0.76 10.4 0.3 3.9 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 PPR_2 PF13041.6 KEG12824.1 - 9e-44 147.5 7.1 1.1e-14 54.4 0.2 5.5 2 1 4 6 6 6 5 PPR repeat family PPR_3 PF13812.6 KEG12824.1 - 2.9e-40 136.2 1.0 5e-12 45.7 0.0 3.8 1 1 3 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.20 KEG12824.1 - 1.7e-29 100.0 0.1 7.6e-06 25.8 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 KEG12824.1 - 1.3e-26 92.0 0.0 7.4e-05 22.4 0.0 5.6 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 KEG12824.1 - 9.4e-19 67.6 0.7 2e-18 66.5 0.6 1.5 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KEG12824.1 - 0.00026 21.4 0.0 0.62 10.6 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG12824.1 - 0.00054 19.8 0.0 2 8.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12824.1 - 0.002 18.8 8.9 0.62 11.0 0.0 5.3 5 1 2 7 7 7 1 Tetratricopeptide repeat XdhC_CoxI PF02625.16 KEG12824.1 - 0.076 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC and CoxI family TPR_6 PF13174.6 KEG12824.1 - 0.3 11.8 3.0 53 4.8 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 KEG12825.1 - 1.4e-37 127.0 25.9 4.7e-08 33.6 1.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KEG12825.1 - 0.0026 16.5 0.2 0.24 10.0 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KEG12825.1 - 0.031 13.6 0.0 0.22 10.8 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain LRR_4 PF12799.7 KEG12828.1 - 4e-35 119.3 43.6 0.00013 22.3 0.1 14.4 8 4 6 15 15 15 14 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG12828.1 - 1.7e-22 77.5 57.3 0.0019 18.1 0.3 19.0 20 1 0 21 21 21 9 Leucine Rich repeat LRR_8 PF13855.6 KEG12828.1 - 8.1e-21 73.6 38.4 0.02 14.6 2.8 11.7 6 3 12 18 18 18 16 Leucine rich repeat LRR_9 PF14580.6 KEG12828.1 - 8.5e-05 22.1 14.3 3.2 7.2 0.1 6.1 2 2 5 7 7 7 3 Leucine-rich repeat LRR_5 PF13306.6 KEG12828.1 - 0.0025 17.8 1.5 0.58 10.1 0.1 4.1 2 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) DUF4549 PF15082.6 KEG12829.1 - 0.28 10.9 4.8 0.25 11.1 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4549) Prominin PF05478.11 KEG12829.1 - 0.3 9.0 4.9 0.074 11.0 0.4 2.0 2 1 0 2 2 2 0 Prominin Bcr-Abl_Oligo PF09036.10 KEG12829.1 - 1.5 8.9 5.4 3.2 7.8 0.3 3.2 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain 2_5_RNA_ligase2 PF13563.6 KEG12830.1 - 1.1e-05 25.4 0.0 0.00085 19.3 0.0 2.4 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily NDUF_B6 PF09782.9 KEG12830.1 - 0.32 11.1 1.4 5 7.2 0.0 2.5 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit MtN3_slv PF03083.16 KEG12831.1 - 7.5e-31 106.0 12.2 1.1e-16 60.6 1.5 2.4 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 KEG12831.1 - 0.012 15.7 0.4 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain PQ-loop PF04193.14 KEG12831.1 - 0.021 14.6 0.1 0.021 14.6 0.1 4.0 5 1 1 6 6 6 0 PQ loop repeat DUF2070 PF09843.9 KEG12831.1 - 2.5 6.3 8.1 3.1 6.0 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NPV_P10 PF05531.12 KEG12832.1 - 0.061 13.8 0.1 0.096 13.2 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CHAP PF05257.16 KEG12833.1 - 5.2e-13 49.4 0.2 1.1e-12 48.3 0.2 1.6 1 0 0 1 1 1 1 CHAP domain FtsX PF02687.21 KEG12834.1 - 2.2e-17 63.3 22.9 9.8e-11 42.0 11.2 6.3 7 0 0 7 7 7 2 FtsX-like permease family Aldose_epim PF01263.20 KEG12836.1 - 4.1e-51 174.1 0.0 4.6e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ABC_tran PF00005.27 KEG12839.1 - 3.2e-30 105.4 0.0 5.5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KEG12839.1 - 6.9e-27 94.2 17.0 6.9e-27 94.2 17.0 3.8 5 0 0 5 5 5 1 ABC-2 type transporter AAA_21 PF13304.6 KEG12839.1 - 8.5e-06 25.8 0.1 0.088 12.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEG12839.1 - 8e-05 23.1 0.1 0.00018 21.9 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEG12839.1 - 0.001 19.0 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KEG12839.1 - 0.001 18.8 0.2 0.0024 17.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KEG12839.1 - 0.0041 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KEG12839.1 - 0.0054 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KEG12839.1 - 0.0088 16.6 0.1 0.018 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEG12839.1 - 0.014 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KEG12839.1 - 0.023 14.9 0.3 0.36 11.1 0.0 3.0 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KEG12839.1 - 0.066 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KEG12839.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Vma12 PF11712.8 KEG12839.1 - 0.17 11.9 1.1 6.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase AAA_28 PF13521.6 KEG12839.1 - 0.19 12.0 0.6 0.35 11.1 0.6 1.4 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.12 KEG12840.1 - 5.6e-29 100.2 5.5 5.6e-29 100.2 5.5 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEG12840.1 - 3e-24 85.4 0.1 5.6e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEG12840.1 - 1.3e-06 28.1 1.0 2.2e-06 27.3 1.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KEG12840.1 - 4.2e-05 23.0 0.2 6.8e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEG12840.1 - 6.7e-05 22.3 1.0 0.00012 21.5 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KEG12840.1 - 0.0054 17.8 0.0 0.0089 17.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KEG12840.1 - 0.0066 16.6 0.5 0.011 15.9 0.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PPL4 PF18188.1 KEG12841.1 - 8.7e-30 103.8 0.1 1.7e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 Prim-pol 4 La_HTH_kDCL PF18177.1 KEG12841.1 - 2.9e-16 59.5 0.1 6e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 La HTH in kinetoplastid DICER domain KptA_kDCL PF18176.1 KEG12841.1 - 1.5e-12 47.7 0.1 4.2e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 KptA in kinetoplastid DICER domain Ribonucleas_3_3 PF14622.6 KEG12841.1 - 0.0009 19.4 0.0 0.11 12.7 0.0 2.9 1 1 1 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KEG12841.1 - 0.018 15.6 0.4 4.2 8.1 0.0 3.2 2 1 1 3 3 3 0 Ribonuclease III domain DUF4212 PF13937.6 KEG12842.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) GAGE PF05831.11 KEG12843.1 - 0.012 16.2 0.8 0.018 15.6 0.8 1.3 1 0 0 1 1 1 0 GAGE protein PBP PF01161.20 KEG12846.1 - 0.00019 21.7 0.0 0.00054 20.3 0.0 1.7 1 1 1 2 2 2 1 Phosphatidylethanolamine-binding protein DAZAP2 PF11029.8 KEG12846.1 - 0.0094 16.9 1.1 0.021 15.7 0.2 2.0 1 1 0 2 2 2 1 DAZ associated protein 2 (DAZAP2) RGS-like PF09128.11 KEG12847.1 - 0.0052 16.5 0.7 0.0052 16.5 0.7 2.7 3 1 1 4 4 4 1 Regulator of G protein signalling-like domain ACC_epsilon PF13822.6 KEG12847.1 - 5.2 7.8 13.1 0.61 10.8 2.0 3.4 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit PUF PF00806.19 KEG12848.1 - 1.3e-21 75.0 0.0 0.025 14.3 0.0 8.8 8 1 1 9 9 9 4 Pumilio-family RNA binding repeat Sigma70_ner PF04546.13 KEG12848.1 - 0.0084 16.0 6.2 0.019 14.8 6.2 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF1414 PF07208.11 KEG12848.1 - 0.011 15.7 0.0 0.09 12.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) Hamartin PF04388.12 KEG12848.1 - 0.013 14.2 1.7 0.021 13.5 1.7 1.2 1 0 0 1 1 1 0 Hamartin protein CDC45 PF02724.14 KEG12848.1 - 0.018 13.3 6.9 0.033 12.5 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein UPF0565 PF10561.9 KEG12848.1 - 0.023 13.9 0.6 0.047 12.9 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RRN3 PF05327.11 KEG12848.1 - 0.043 12.4 3.2 0.067 11.7 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 APH PF01636.23 KEG12848.1 - 0.14 12.1 2.1 0.23 11.4 2.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sporozoite_P67 PF05642.11 KEG12848.1 - 0.5 8.4 7.0 0.75 7.8 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF913 PF06025.12 KEG12848.1 - 0.99 8.3 3.9 0.65 8.9 1.7 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF1682 PF07946.14 KEG12848.1 - 1.4 8.1 9.2 2.5 7.2 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 KEG12848.1 - 1.4 8.7 9.1 0.25 11.1 4.0 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TFB6 PF17110.5 KEG12848.1 - 2.1 8.1 5.1 6.3 6.5 5.1 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Vfa1 PF08432.10 KEG12848.1 - 3.2 8.1 11.9 0.18 12.1 6.4 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.16 KEG12848.1 - 8.6 5.5 8.9 17 4.5 8.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit WW PF00397.26 KEG12849.1 - 2.2e-11 43.6 0.8 3.9e-11 42.8 0.8 1.4 1 0 0 1 1 1 1 WW domain zf-CCCH_4 PF18044.1 KEG12849.1 - 0.00011 21.9 1.3 0.00019 21.1 1.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG12849.1 - 0.0062 16.6 1.8 0.012 15.6 1.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KEG12849.1 - 0.016 15.1 0.4 0.026 14.5 0.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SpoU_methylase PF00588.19 KEG12850.1 - 4.6e-08 33.4 0.3 0.0016 18.6 0.0 3.9 3 1 0 3 3 3 2 SpoU rRNA Methylase family FBPase_3 PF01950.16 KEG12851.1 - 0.0065 15.7 0.0 0.0097 15.1 0.0 1.1 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase Cwf_Cwc_15 PF04889.12 KEG12851.1 - 0.041 13.6 1.7 0.1 12.3 1.7 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1619 PF07773.11 KEG12853.1 - 7.2e-43 147.7 0.6 1.9e-41 143.0 1.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) WD40 PF00400.32 KEG12855.1 - 8.7e-14 51.7 7.5 0.015 16.2 0.2 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 KEG12855.1 - 0.086 12.1 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain DUF2749 PF10907.8 KEG12855.1 - 0.68 10.1 2.3 0.83 9.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) EF-hand_7 PF13499.6 KEG12857.1 - 2.4e-11 43.9 3.6 2.9e-11 43.6 1.7 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG12857.1 - 7.9e-09 34.8 1.8 1.4e-05 24.6 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEG12857.1 - 9.4e-08 31.1 1.4 0.00022 20.5 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KEG12857.1 - 5.5e-06 26.1 1.8 4.5e-05 23.2 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain pair Hormone_3 PF00159.18 KEG12857.1 - 0.025 14.6 1.4 0.15 12.1 0.0 2.4 3 0 0 3 3 3 0 Pancreatic hormone peptide DUF5638 PF18688.1 KEG12857.1 - 0.039 14.3 0.1 0.049 14.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5638) EF-hand_14 PF17959.1 KEG12857.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 KEG12857.1 - 0.12 12.0 0.2 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 EF hand F-box-like PF12937.7 KEG12858.1 - 0.055 13.4 0.2 0.15 12.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KEG12858.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 F-box PALP PF00291.25 KEG12860.1 - 8.3e-63 212.5 2.3 9.4e-63 212.3 2.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2009 PF09418.10 KEG12861.1 - 2.1e-153 511.7 0.0 2.6e-153 511.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) LOH1CR12 PF10158.9 KEG12861.1 - 0.037 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor protein PCRF PF03462.18 KEG12861.1 - 0.16 11.8 0.1 0.47 10.3 0.1 1.7 1 1 0 1 1 1 0 PCRF domain Sipho_Gp157 PF05565.11 KEG12862.1 - 0.035 14.1 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 Mis14 PF08641.12 KEG12862.1 - 0.1 12.9 1.7 0.39 11.0 1.7 2.0 1 1 0 1 1 1 0 Kinetochore protein Mis14 like SRP54 PF00448.22 KEG12863.1 - 4e-55 186.5 0.1 8.8e-55 185.4 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 KEG12863.1 - 2.2e-15 57.3 7.3 8.7e-15 55.4 7.3 1.8 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 KEG12863.1 - 3.3e-08 33.6 0.0 8.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 KEG12863.1 - 8.5e-06 25.2 0.0 2.6e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KEG12863.1 - 1e-05 25.8 0.1 6.1e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEG12863.1 - 0.00012 21.8 1.4 0.00015 21.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KEG12863.1 - 0.00015 21.8 0.4 0.25 11.2 0.0 2.8 2 1 0 3 3 3 2 NTPase CbiA PF01656.23 KEG12863.1 - 0.00071 19.6 0.2 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KEG12863.1 - 0.0015 18.3 0.0 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KEG12863.1 - 0.0021 17.3 0.0 0.04 13.1 0.0 2.4 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_33 PF13671.6 KEG12863.1 - 0.0027 17.9 0.0 0.0089 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEG12863.1 - 0.0078 16.1 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KEG12863.1 - 0.0084 16.0 0.0 0.4 10.6 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase cobW PF02492.19 KEG12863.1 - 0.0085 15.7 0.1 0.022 14.3 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KEG12863.1 - 0.0092 16.4 0.0 0.033 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ETF PF01012.21 KEG12863.1 - 0.0097 15.8 0.1 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 Electron transfer flavoprotein domain MeaB PF03308.16 KEG12863.1 - 0.01 14.8 0.1 0.049 12.6 0.1 2.0 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KEG12863.1 - 0.012 15.7 0.1 0.058 13.5 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG12863.1 - 0.014 15.8 0.2 0.059 13.7 0.0 2.2 2 1 0 2 2 1 0 AAA ATPase domain AAA_31 PF13614.6 KEG12863.1 - 0.014 15.3 0.0 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KEG12863.1 - 0.015 15.8 0.0 0.068 13.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Metallophos_3 PF14582.6 KEG12863.1 - 0.017 14.5 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily AAA_19 PF13245.6 KEG12863.1 - 0.02 15.2 0.1 0.064 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEG12863.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.20 KEG12863.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 KEG12863.1 - 0.031 13.5 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 KEG12863.1 - 0.043 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FAD_binding_4 PF01565.23 KEG12863.1 - 0.09 12.5 0.2 16 5.3 0.1 2.6 2 1 0 2 2 2 0 FAD binding domain Metallophos PF00149.28 KEG12863.1 - 0.17 12.4 0.1 5.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase B12-binding PF02310.19 KEG12863.1 - 0.22 11.6 1.3 0.5 10.4 0.1 2.1 2 1 0 2 2 1 0 B12 binding domain UvrD-helicase PF00580.21 KEG12863.1 - 0.27 10.7 0.9 1.3 8.4 0.7 2.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain SQS_PSY PF00494.19 KEG12865.1 - 1.3e-10 41.2 0.1 2.2e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase TPR_11 PF13414.6 KEG12867.1 - 1.1e-05 25.0 0.5 0.026 14.2 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 KEG12867.1 - 0.00023 20.8 2.4 0.7 9.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12867.1 - 0.001 19.0 8.8 0.041 14.0 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG12867.1 - 0.038 14.4 0.3 0.83 10.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG12867.1 - 0.064 13.8 1.4 0.064 13.8 1.4 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG12867.1 - 0.43 11.3 11.8 0.42 11.3 3.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG12867.1 - 0.57 10.5 5.3 2.6 8.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12867.1 - 0.78 10.7 5.1 1 10.3 0.8 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 KEG12868.1 - 7.2e-33 112.2 0.2 9.7e-33 111.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KEG12868.1 - 2.7e-27 94.4 8.7 4.1e-27 93.8 8.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KEG12868.1 - 6.6e-17 61.1 0.3 9.9e-17 60.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEG12868.1 - 9.9e-05 22.7 0.0 0.00042 20.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KEG12868.1 - 0.003 17.9 0.1 0.0055 17.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KEG12868.1 - 0.0051 16.7 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEG12868.1 - 0.0067 16.5 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KEG12868.1 - 0.043 13.9 1.0 4.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KEG12868.1 - 0.085 13.4 0.0 0.11 13.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain PhoLip_ATPase_C PF16212.5 KEG12869.1 - 8.7e-57 192.7 13.2 1.6e-56 191.8 13.2 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEG12869.1 - 4.8e-23 80.6 0.2 1.1e-22 79.5 0.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEG12869.1 - 9.1e-09 35.9 0.0 0.0094 16.2 0.0 3.6 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEG12869.1 - 2e-05 24.2 0.1 2e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEG12869.1 - 0.015 15.4 0.1 0.36 10.9 0.0 2.8 3 0 0 3 3 3 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEG12869.1 - 0.024 14.4 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TetR_C_28 PF17937.1 KEG12869.1 - 0.085 13.3 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L2_C PF03947.18 KEG12870.1 - 3.6e-20 72.4 0.2 6.4e-20 71.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.18 KEG12871.1 - 2.4e-36 124.0 0.3 5.5e-36 122.8 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEG12871.1 - 6.4e-19 68.2 0.1 1.1e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-Tim10_DDP PF02953.15 KEG12872.1 - 1.2e-14 53.7 2.0 1.6e-14 53.3 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2630 PF10944.8 KEG12872.1 - 0.73 10.3 3.3 2.6 8.6 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2630) PPR_long PF17177.4 KEG12873.1 - 0.039 13.3 0.1 13 5.1 0.0 2.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP SspB PF04386.13 KEG12873.1 - 0.1 12.5 0.0 22 4.9 0.2 2.6 1 1 0 2 2 2 0 Stringent starvation protein B Pkinase PF00069.25 KEG12875.1 - 2.2e-28 99.4 0.0 4.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12875.1 - 2e-17 63.4 0.0 1.5e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG12875.1 - 0.0068 15.8 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KEG12876.1 - 1.4e-20 73.8 0.0 2.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12876.1 - 6.4e-12 45.3 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PMP1_2 PF08114.11 KEG12876.1 - 0.061 13.1 1.0 0.19 11.5 1.0 1.9 1 0 0 1 1 1 0 ATPase proteolipid family Reticulon PF02453.17 KEG12877.1 - 9.8e-24 84.1 2.7 1.7e-23 83.3 2.7 1.4 1 1 0 1 1 1 1 Reticulon DUF3927 PF13064.6 KEG12877.1 - 0.00018 21.4 6.7 0.031 14.2 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3927) DnaJ PF00226.31 KEG12878.1 - 2.4e-07 30.8 0.0 5.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Toxin_13 PF07822.11 KEG12878.1 - 0.13 12.4 2.8 0.32 11.1 2.8 1.6 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Leu_Phe_trans PF03588.14 KEG12879.1 - 4.3e-06 26.4 0.1 6.5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 KEG12879.1 - 0.0098 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FTHFS PF01268.19 KEG12880.1 - 3.3e-252 837.6 0.0 3.7e-252 837.5 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.22 KEG12882.1 - 8.8e-11 41.5 0.0 2e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 KEG12884.1 - 5.4e-14 52.7 0.0 9.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KEG12884.1 - 1.2e-12 48.0 0.0 2.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KEG12884.1 - 9.9e-12 44.9 0.0 2.6e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 KEG12884.1 - 6e-07 29.4 0.0 2.8e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KEG12884.1 - 3e-06 27.3 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 KEG12884.1 - 7.8e-06 25.9 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG12884.1 - 1.8e-05 25.1 0.0 5.7e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG12884.1 - 2.5e-05 24.7 1.0 0.00054 20.4 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KEG12884.1 - 0.00029 20.6 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KEG12884.1 - 0.00036 20.6 0.0 0.0014 18.6 0.0 1.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG12884.1 - 0.00087 19.1 0.1 0.096 12.5 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 KEG12884.1 - 0.001 19.1 0.0 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KEG12884.1 - 0.0025 18.1 0.0 0.006 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 KEG12884.1 - 0.0033 16.8 0.1 0.0094 15.4 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEG12884.1 - 0.0044 17.2 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KEG12884.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KEG12884.1 - 0.0086 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG12884.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PikAIV_N PF18605.1 KEG12884.1 - 0.021 14.4 0.5 0.05 13.2 0.5 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AAA_5 PF07728.14 KEG12884.1 - 0.021 14.8 0.0 0.067 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KEG12884.1 - 0.026 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_32 PF13654.6 KEG12884.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEG12884.1 - 0.029 14.6 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEG12884.1 - 0.045 14.3 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEG12884.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KEG12884.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KEG12884.1 - 0.091 12.6 0.1 0.57 10.0 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEG12884.1 - 0.097 12.2 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KEG12884.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KEG12884.1 - 0.16 11.8 0.0 0.47 10.4 0.0 1.8 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.6 KEG12884.1 - 0.17 12.4 0.0 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG12884.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KEG12884.1 - 0.18 11.7 0.0 0.83 9.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ubiquitin PF00240.23 KEG12889.1 - 0.0036 17.0 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ig_4 PF16680.5 KEG12889.1 - 0.047 13.9 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain TPR_12 PF13424.6 KEG12890.1 - 3.9e-05 23.8 13.6 0.0005 20.3 3.3 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG12890.1 - 0.33 11.2 10.5 2.4 8.5 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG12890.1 - 1.4 8.8 4.4 19 5.3 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG12890.1 - 4.2 8.2 8.3 3.9 8.3 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ATG27 PF09451.10 KEG12891.1 - 7.2e-05 22.8 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF4307 PF14155.6 KEG12891.1 - 0.043 13.7 3.8 0.059 13.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) TPT PF03151.16 KEG12894.1 - 1.2e-10 41.2 22.3 1.5e-10 40.9 22.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family SH3_9 PF14604.6 KEG12895.1 - 4.7e-09 36.0 0.1 7.8e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEG12895.1 - 1.9e-08 33.9 0.2 3.9e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEG12895.1 - 1.7e-07 30.7 0.0 3.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Tmemb_cc2 PF10267.9 KEG12895.1 - 5.4e-06 25.8 0.1 6.7e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein CortBP2 PF09727.9 KEG12895.1 - 5.1e-05 23.3 3.8 7.3e-05 22.8 3.8 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 ATG16 PF08614.11 KEG12895.1 - 0.0049 17.1 7.5 0.0067 16.7 7.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SH3_3 PF08239.11 KEG12895.1 - 0.0063 16.8 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Filament PF00038.21 KEG12895.1 - 0.014 15.0 2.6 0.014 15.0 2.6 1.3 1 1 0 1 1 1 0 Intermediate filament protein CASP_C PF08172.12 KEG12895.1 - 0.038 13.3 2.1 0.05 12.9 2.1 1.2 1 0 0 1 1 1 0 CASP C terminal DUF3584 PF12128.8 KEG12895.1 - 0.16 9.5 6.4 0.19 9.2 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 KEG12895.1 - 0.31 11.5 2.9 4.7 7.7 1.8 2.4 2 1 0 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 KEG12895.1 - 0.5 9.2 6.2 0.68 8.7 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tmemb_9 PF05434.11 KEG12895.1 - 4.3 7.2 6.1 1.4 8.8 2.2 2.0 1 1 1 2 2 2 0 TMEM9 LRR_6 PF13516.6 KEG12896.1 - 0.00083 19.2 0.0 1.2 9.4 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 KEG12896.1 - 0.0029 18.0 5.6 0.22 12.0 0.0 3.8 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG12896.1 - 0.015 15.7 2.2 6.8 7.7 0.0 4.5 3 2 0 3 3 3 0 Leucine Rich Repeat Fmp27_WPPW PF10359.9 KEG12897.1 - 0.013 14.3 0.3 0.013 14.3 0.3 1.7 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain CREPT PF16566.5 KEG12897.1 - 8.6 6.5 11.3 4.5 7.4 4.8 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour KASH PF10541.9 KEG12898.1 - 0.099 12.9 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF1907 PF08925.11 KEG12899.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) MFS_1 PF07690.16 KEG12900.1 - 3.1e-11 42.8 27.9 3.1e-11 42.8 27.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG12900.1 - 5e-05 22.9 8.3 5e-05 22.9 8.3 2.7 3 0 0 3 3 3 1 Nodulin-like GlcNAc_2-epim PF07221.11 KEG12901.1 - 9.1e-53 179.7 0.4 1.1e-52 179.4 0.4 1.0 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) PPR PF01535.20 KEG12901.1 - 0.19 12.0 1.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 PPR repeat TPR_2 PF07719.17 KEG12902.1 - 2.6e-05 24.0 0.7 0.28 11.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG12902.1 - 0.0023 17.6 0.1 7.3 6.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG12902.1 - 3.3 8.4 8.8 8.2 7.2 0.2 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG12902.1 - 5.7 8.0 13.0 1.5 9.9 0.9 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Repressor_Mnt PF11423.8 KEG12905.1 - 0.063 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Regulatory protein Mnt TP6A_N PF04406.14 KEG12906.1 - 3.6e-10 39.7 0.1 8.2e-10 38.5 0.1 1.6 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 KEG12906.1 - 0.0056 16.6 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) REV PF00424.18 KEG12906.1 - 0.027 14.5 0.4 0.074 13.1 0.4 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) NDK PF00334.19 KEG12907.1 - 0.035 14.1 0.0 12 6.0 0.0 3.8 4 0 0 4 4 4 0 Nucleoside diphosphate kinase NDK PF00334.19 KEG12908.1 - 5.1e-12 46.0 0.0 0.052 13.6 0.0 7.5 7 0 0 7 7 7 4 Nucleoside diphosphate kinase HTH_Mga PF08280.11 KEG12908.1 - 0.48 10.5 2.0 0.63 10.1 0.5 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain DUF4799 PF16056.5 KEG12908.1 - 1.7 7.7 7.5 3.6 6.7 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) CAP_N PF01213.19 KEG12911.1 - 0.058 12.9 0.2 0.089 12.3 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KEG12911.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator HA2 PF04408.23 KEG12912.1 - 2.4e-18 66.4 0.0 4.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEG12912.1 - 1.6e-16 60.5 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEG12912.1 - 4.9e-13 49.4 0.0 1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gryzun-like PF12742.7 KEG12913.1 - 0.0078 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF3320 PF11784.8 KEG12913.1 - 0.15 12.0 0.3 0.43 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) MMS19_N PF14500.6 KEG12914.1 - 2.3e-37 129.0 3.5 1.2e-35 123.4 1.4 2.7 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II Thymidylate_kin PF02223.17 KEG12915.1 - 1.5e-17 63.9 0.0 2.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase MeaB PF03308.16 KEG12915.1 - 0.0055 15.7 0.1 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PPK2 PF03976.14 KEG12915.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Ribosomal_L35Ae PF01247.18 KEG12916.1 - 6.1e-37 125.7 0.4 9.6e-37 125.0 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KEG12916.1 - 0.0028 17.8 0.3 1.4 9.2 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain YdiH PF15930.5 KEG12917.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Myosin_head PF00063.21 KEG12919.1 - 1.8e-164 548.7 0.0 5e-164 547.2 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 KEG12919.1 - 0.003 17.9 0.1 0.079 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Microtub_bd PF16796.5 KEG12919.1 - 0.032 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding adh_short PF00106.25 KEG12920.1 - 9.4e-27 93.7 0.0 1.6e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEG12920.1 - 5.4e-16 58.9 0.0 4.6e-11 42.7 0.0 2.7 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG12920.1 - 9.8e-05 22.3 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 KR domain SRP40_C PF05022.12 KEG12922.1 - 1.4e-12 48.2 1.9 2.2e-12 47.6 1.9 1.3 1 0 0 1 1 1 1 SRP40, C-terminal domain WD40 PF00400.32 KEG12923.1 - 2.3e-38 129.5 23.0 8.1e-09 36.0 1.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG12923.1 - 5e-08 33.1 1.4 0.0098 16.2 0.0 5.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PSP1 PF04468.12 KEG12924.1 - 3.4e-22 78.5 1.5 7.1e-22 77.5 1.5 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PAM2 PF07145.15 KEG12924.1 - 0.43 10.4 4.5 0.93 9.3 4.5 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region XhlA PF10779.9 KEG12925.1 - 0.014 15.6 2.3 0.033 14.4 0.3 2.4 2 0 0 2 2 2 0 Haemolysin XhlA WASH_WAHD PF11945.8 KEG12925.1 - 0.054 13.0 0.3 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 WAHD domain of WASH complex Not3 PF04065.15 KEG12925.1 - 0.12 11.8 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Snapin_Pallidin PF14712.6 KEG12925.1 - 0.18 12.2 4.3 9 6.8 0.5 3.1 2 1 0 2 2 2 0 Snapin/Pallidin DUF16 PF01519.16 KEG12925.1 - 0.37 11.3 2.8 0.41 11.2 1.0 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 DUF2730 PF10805.8 KEG12925.1 - 0.58 10.3 2.9 1.3 9.1 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Suppressor_APC PF11414.8 KEG12925.1 - 0.62 10.2 4.3 1.7 8.8 1.7 2.9 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF4140 PF13600.6 KEG12925.1 - 0.7 10.4 12.3 8.4 6.9 0.2 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 KEG12925.1 - 1.1 8.3 10.4 0.03 13.4 3.8 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SUIM_assoc PF16619.5 KEG12925.1 - 3.5 7.7 7.4 6.4 6.9 1.0 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Allexi_40kDa PF05549.11 KEG12925.1 - 3.7 7.0 5.3 21 4.5 1.0 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.24 KEG12925.1 - 7.6 6.4 6.5 2.3 8.1 0.8 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DEAD PF00270.29 KEG12926.1 - 8.3e-44 149.4 0.0 2.2e-41 141.6 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG12926.1 - 3.1e-30 104.7 0.0 7.9e-27 93.8 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KEG12926.1 - 1.2e-06 28.6 0.0 1.4e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit KIP1 PF07765.12 KEG12926.1 - 0.19 11.9 0.1 0.44 10.7 0.1 1.6 1 0 0 1 1 1 0 KIP1-like protein Kinesin PF00225.23 KEG12928.1 - 3.8e-81 272.6 8.8 1.1e-49 169.1 0.0 3.4 4 1 0 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 KEG12928.1 - 1.5e-19 70.4 2.5 2.7e-19 69.6 0.0 2.5 2 1 0 2 2 2 1 Microtubule binding AAA_25 PF13481.6 KEG12928.1 - 0.45 10.1 5.3 0.72 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KEG12928.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.9 4 2 0 4 4 4 0 AAA domain zf-CRD PF17979.1 KEG12929.1 - 6.3e-41 140.1 9.3 6.3e-41 140.1 9.3 2.4 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 KEG12929.1 - 1.7e-15 57.1 0.1 3.1e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 KEG12929.1 - 2.7e-07 30.4 7.4 7.7e-07 29.0 7.4 1.9 1 0 0 1 1 1 1 PBZ domain zf-C3HC4_3 PF13920.6 KEG12929.1 - 4.2e-07 29.7 8.4 4.2e-07 29.7 8.4 4.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG12929.1 - 6.3e-07 29.2 11.0 6.3e-07 29.2 11.0 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FHA_2 PF17913.1 KEG12929.1 - 3.7e-06 27.1 0.1 7.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 KEG12929.1 - 6.2e-06 26.0 11.8 6.2e-06 26.0 11.8 4.4 5 1 1 6 6 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG12929.1 - 2.8e-05 24.1 10.1 2.8e-05 24.1 10.1 3.6 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEG12929.1 - 3.4e-05 24.1 11.1 3.4e-05 24.1 11.1 4.8 5 2 1 6 6 4 1 Ring finger domain zf-RING_5 PF14634.6 KEG12929.1 - 0.00029 20.7 9.7 0.00029 20.7 9.7 4.4 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_6 PF14835.6 KEG12929.1 - 0.00038 20.3 6.1 0.00038 20.3 6.1 3.1 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KEG12929.1 - 0.0054 17.0 5.1 0.0054 17.0 5.1 3.3 4 1 0 4 4 3 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.5 KEG12929.1 - 0.0087 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_4 PF15227.6 KEG12929.1 - 0.017 15.3 10.7 0.017 15.3 10.7 3.7 4 1 1 5 5 4 0 zinc finger of C3HC4-type, RING TANGO2 PF05742.12 KEG12930.1 - 1.3e-26 94.2 0.0 1.6e-14 54.6 0.0 2.6 2 1 0 2 2 2 2 Transport and Golgi organisation 2 DUF4586 PF15239.6 KEG12931.1 - 1.2e-34 120.9 3.7 1.6e-34 120.5 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.10 KEG12932.1 - 1.4e-77 260.8 0.0 2.1e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KEG12932.1 - 0.0018 18.7 1.7 0.0018 18.7 1.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AAA_2 PF07724.14 KEG12933.1 - 3.5e-42 144.4 0.2 7.6e-34 117.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KEG12933.1 - 2e-12 47.6 1.3 7.2e-05 23.2 0.1 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEG12933.1 - 1.9e-06 27.9 0.2 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KEG12933.1 - 2.1e-06 27.7 0.3 2.1e-06 27.7 0.3 3.0 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 KEG12933.1 - 1.7e-05 25.1 0.1 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 KEG12933.1 - 2.9e-05 23.3 0.0 0.0021 17.2 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain AAA_18 PF13238.6 KEG12933.1 - 0.0012 19.4 0.4 0.0047 17.5 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 KEG12933.1 - 0.0042 17.5 2.7 0.0092 16.4 0.9 2.4 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 KEG12933.1 - 0.0044 16.8 0.0 0.062 13.0 0.0 2.6 2 1 1 3 3 3 1 Sigma-54 interaction domain RuvB_N PF05496.12 KEG12933.1 - 0.0087 15.8 0.1 0.75 9.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KEG12933.1 - 0.011 16.1 0.0 0.09 13.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEG12933.1 - 0.014 15.6 0.4 0.071 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEG12933.1 - 0.015 15.5 0.1 0.055 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEG12933.1 - 0.024 14.0 0.1 0.12 11.8 0.0 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KEG12933.1 - 0.03 13.6 0.1 0.088 12.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KEG12933.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KEG12933.1 - 0.056 13.9 0.0 0.95 10.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter IPT PF01745.16 KEG12933.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase KfrA_N PF11740.8 KEG12933.1 - 0.072 13.8 1.3 5.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term TniB PF05621.11 KEG12933.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein CPT PF07931.12 KEG12933.1 - 0.078 12.8 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 KEG12933.1 - 0.079 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KEG12933.1 - 0.081 12.5 0.1 12 5.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEG12933.1 - 0.095 12.6 0.7 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 NTPase UCH PF00443.29 KEG12934.1 - 2.2e-37 129.0 0.0 3.6e-37 128.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG12934.1 - 4.6e-08 33.0 0.0 1e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Wap1 PF16997.5 KEG12934.1 - 0.052 12.7 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 Wap1 domain MCM PF00493.23 KEG12935.1 - 9.3e-95 316.0 0.0 1.4e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEG12935.1 - 3.9e-33 114.0 0.0 8.7e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEG12935.1 - 3.2e-23 82.0 4.5 6e-23 81.1 4.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 KEG12935.1 - 9.4e-11 41.9 0.0 2.3e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 KEG12935.1 - 3.7e-10 40.3 0.0 1.2e-09 38.7 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEG12935.1 - 6.4e-08 32.2 0.1 6.8e-06 25.6 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEG12935.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG12935.1 - 0.0028 18.0 1.2 0.43 11.0 0.1 4.0 3 2 0 4 4 4 1 AAA ATPase domain NTPase_1 PF03266.15 KEG12935.1 - 0.0063 16.4 0.1 1.8 8.4 0.1 2.6 1 1 1 2 2 2 2 NTPase Sigma54_activat PF00158.26 KEG12935.1 - 0.015 15.0 0.3 0.56 9.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain DLIC PF05783.11 KEG12936.1 - 1.2e-07 31.0 2.9 3e-07 29.6 0.1 2.4 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) MFS_1 PF07690.16 KEG12937.1 - 6.6e-33 114.1 35.1 3e-16 59.3 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG12937.1 - 1.2e-05 24.4 24.3 0.0014 17.5 9.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KEG12937.1 - 0.00033 19.6 17.0 0.037 12.9 2.4 2.1 2 0 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KEG12937.1 - 0.00075 18.2 1.1 0.00075 18.2 1.1 3.5 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like OATP PF03137.20 KEG12937.1 - 0.017 13.4 0.5 0.017 13.4 0.5 3.0 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Alpha-mann_mid PF09261.11 KEG12938.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha mannosidase middle domain TPR_20 PF14561.6 KEG12938.1 - 0.11 12.9 0.1 7.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 KEG12939.1 - 0.00011 22.2 2.1 0.039 14.0 0.0 2.4 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 LCE6A PF15858.5 KEG12939.1 - 0.44 11.3 6.5 0.2 12.4 0.4 2.5 2 0 0 2 2 2 0 Late cornified envelope protein 6A family KCNQ2_u3 PF16642.5 KEG12939.1 - 1.4 10.0 5.4 1.4 10.0 0.4 2.4 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Spt20 PF12090.8 KEG12939.1 - 6 6.4 8.7 5.5 6.5 3.1 2.1 2 0 0 2 2 2 0 Spt20 family Kinesin PF00225.23 KEG12940.1 - 1.1e-17 64.0 0.0 1.6e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG12940.1 - 2.3e-08 34.1 0.0 1.4e-07 31.5 0.1 2.1 2 1 0 2 2 2 1 Microtubule binding RNaseH_pPIWI_RE PF13032.6 KEG12940.1 - 0.076 12.9 0.3 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 RNaseH domain of pPIWI_RE AAA_7 PF12775.7 KEG12940.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region TGT PF01702.18 KEG12941.1 - 2e-35 122.6 0.7 1.2e-33 116.8 0.7 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Myosin_head PF00063.21 KEG12942.1 - 7.1e-175 583.0 0.0 9.3e-175 582.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KEG12942.1 - 0.0029 17.2 0.3 0.0029 17.2 0.3 3.1 3 0 0 3 3 3 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KEG12942.1 - 0.071 13.4 0.7 0.35 11.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG12942.1 - 0.099 12.7 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KEG12942.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 KEG12943.1 - 2.6e-58 197.1 20.2 5e-58 196.1 20.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEG12943.1 - 5.4e-26 91.2 0.0 2e-25 89.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEG12943.1 - 8.1e-15 55.4 3.1 2.6e-06 27.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEG12943.1 - 1.5e-10 41.4 52.5 1.6e-09 38.0 31.2 4.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEG12943.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2721 PF11026.8 KEG12943.1 - 0.045 13.6 6.5 0.051 13.5 1.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) ABC_tran PF00005.27 KEG12943.1 - 0.12 12.9 0.0 0.12 12.9 0.0 6.5 3 2 0 3 3 1 0 ABC transporter JAB PF01398.21 KEG12943.1 - 0.16 11.9 3.3 0.24 11.4 0.1 3.0 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease V-SNARE_C PF12352.8 KEG12943.1 - 0.19 12.0 12.0 0.61 10.4 0.4 3.8 3 0 0 3 3 2 0 Snare region anchored in the vesicle membrane C-terminus AAA_23 PF13476.6 KEG12943.1 - 0.99 9.9 110.7 0.099 13.1 58.1 6.4 2 2 1 3 3 1 0 AAA domain Mating_N PF12731.7 KEG12943.1 - 3.5 7.8 9.5 0.3 11.2 0.2 3.9 4 0 0 4 4 4 0 Mating-type protein beta 1 SET PF00856.28 KEG12945.1 - 1.7e-09 38.3 0.0 4.8e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 SET domain LRR_6 PF13516.6 KEG12946.1 - 2.8e-07 30.0 0.2 0.079 13.1 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 KEG12946.1 - 0.063 13.8 0.1 80 4.4 0.1 4.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 KEG12946.1 - 0.064 13.0 1.0 3.6 7.4 0.1 3.6 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KEG12946.1 - 0.069 13.6 0.3 23 5.6 0.0 3.4 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) SCP2_2 PF13530.6 KEG12948.1 - 0.066 13.6 1.1 0.16 12.4 0.2 2.0 2 0 0 2 2 2 0 Sterol carrier protein domain LysM PF01476.20 KEG12949.1 - 2.1e-10 40.5 0.0 0.00025 21.0 0.0 2.5 2 0 0 2 2 2 2 LysM domain eIF2A PF08662.11 KEG12950.1 - 4e-42 144.3 0.0 1.6e-32 113.0 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF1738 PF08401.11 KEG12952.1 - 1.6e-06 28.3 0.0 0.013 15.6 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1738) Macoilin PF09726.9 KEG12955.1 - 0.38 9.2 7.4 0.46 9.0 7.4 1.1 1 0 0 1 1 1 0 Macoilin family SKA1 PF07160.12 KEG12955.1 - 0.82 9.5 3.6 1.2 8.9 3.6 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Peptidase_S28 PF05577.12 KEG12956.1 - 1.2e-48 166.0 0.0 1.7e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 ILEI PF15711.5 KEG12956.1 - 0.035 14.6 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Interleukin-like EMT inducer Dpy-30 PF05186.13 KEG12957.1 - 0.00027 20.6 1.0 0.59 9.9 0.0 2.2 2 0 0 2 2 2 2 Dpy-30 motif Importin_rep_4 PF18808.1 KEG12959.1 - 4.9e-13 49.2 9.7 3.9e-10 39.9 0.0 5.0 4 1 1 5 5 5 2 Importin repeat HEAT_EZ PF13513.6 KEG12959.1 - 2.6e-09 37.4 6.4 0.0019 18.7 0.1 7.1 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 KEG12959.1 - 3.4e-06 26.8 18.5 0.0082 16.3 0.1 7.5 9 0 0 9 9 7 2 HEAT repeat Cnd1 PF12717.7 KEG12959.1 - 5.1e-06 26.6 0.3 0.014 15.5 0.1 3.1 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 KEG12959.1 - 3.4e-05 23.5 0.0 0.43 10.1 0.0 4.0 2 1 1 3 3 3 1 Tti2 family HEAT_2 PF13646.6 KEG12959.1 - 5.4e-05 23.5 6.2 0.011 16.1 0.1 5.2 3 2 2 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 KEG12959.1 - 5.7e-05 21.9 0.9 0.014 14.0 0.0 3.6 3 3 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KEG12959.1 - 7.3e-05 23.3 0.6 5.8 7.6 0.1 4.5 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KEG12959.1 - 0.0045 16.6 0.1 6.8 6.2 0.0 4.5 4 1 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 KEG12959.1 - 0.034 14.3 0.5 1.5 9.1 0.0 3.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 KEG12959.1 - 0.076 12.9 2.6 46 3.9 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KEG12959.1 - 0.78 8.8 5.6 16 4.5 0.0 4.2 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal Urb2 PF10441.9 KEG12959.1 - 4.3 7.2 5.5 72 3.2 0.1 4.1 3 1 1 4 4 4 0 Urb2/Npa2 family DUF3021 PF11457.8 KEG12960.1 - 0.025 14.9 0.8 0.057 13.7 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) RRM_1 PF00076.22 KEG12961.1 - 4e-09 36.2 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 KEG12961.1 - 5.9e-06 26.6 0.0 5.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Pheromone PF08015.11 KEG12961.1 - 0.74 10.9 3.0 1.9 9.6 1.6 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone TCR_zetazeta PF11628.8 KEG12962.1 - 0.11 12.2 7.8 0.12 12.1 3.4 3.2 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain Flavi_M PF01004.19 KEG12962.1 - 0.15 11.9 2.2 4.4 7.1 0.1 3.2 3 0 0 3 3 3 0 Flavivirus envelope glycoprotein M SLATT_fungal PF18142.1 KEG12962.1 - 0.69 9.9 3.5 35 4.4 2.0 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2H-phosphodiest PF08975.10 KEG12963.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) PI3_PI4_kinase PF00454.27 KEG12964.1 - 3.5e-17 63.0 0.3 3.5e-17 63.0 0.3 1.8 1 1 1 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TFIIA PF03153.13 KEG12964.1 - 0.12 12.4 8.4 1.6 8.6 3.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 KEG12964.1 - 0.23 10.7 1.4 0.38 9.9 1.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 KEG12964.1 - 0.26 11.0 2.1 0.43 10.3 0.9 1.9 2 0 0 2 2 2 0 Connexin BRF1 PF07741.13 KEG12964.1 - 2.3 8.6 7.9 1.7 9.0 3.8 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NST1 PF13945.6 KEG12964.1 - 3.5 7.7 11.6 0.16 12.1 5.3 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator ATP-synt_E PF05680.12 KEG12964.1 - 4.5 7.7 7.6 13 6.2 7.6 1.8 1 0 0 1 1 1 0 ATP synthase E chain Pex14_N PF04695.13 KEG12964.1 - 8.7 7.0 11.1 14 6.3 4.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc15p PF05841.11 KEG12964.1 - 9.7 7.0 14.4 0.78 10.6 8.6 2.0 2 0 0 2 2 2 0 Apc15p protein Phage_GP20 PF06810.11 KEG12966.1 - 0.0011 18.8 8.9 0.0011 18.8 8.9 2.5 2 1 1 3 3 3 1 Phage minor structural protein GP20 GAS PF13851.6 KEG12966.1 - 0.0084 15.5 13.0 0.0084 15.5 13.0 3.3 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding FAM101 PF15068.6 KEG12966.1 - 0.069 13.1 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 FAM101 family DivIC PF04977.15 KEG12966.1 - 0.072 12.9 0.1 0.072 12.9 0.1 3.9 2 1 0 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 KEG12966.1 - 0.15 12.6 9.4 1.2 9.6 3.4 3.0 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 KEG12966.1 - 0.17 12.1 37.0 3.8 7.7 0.2 3.5 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) EMP24_GP25L PF01105.24 KEG12966.1 - 0.74 9.7 4.0 2.1 8.3 4.0 1.8 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_23 PF13476.6 KEG12966.1 - 0.88 10.0 9.8 1.9 8.9 9.8 1.5 1 0 0 1 1 1 0 AAA domain PRP1_N PF06424.12 KEG12966.1 - 2 8.8 8.4 4.6 7.6 8.4 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal HOOK PF05622.12 KEG12966.1 - 2.3 6.2 25.3 0.66 8.1 21.6 1.8 2 0 0 2 2 2 0 HOOK protein AAA_33 PF13671.6 KEG12966.1 - 3.1 8.0 8.6 8.3 6.6 6.5 2.5 2 0 0 2 2 2 0 AAA domain DUF4618 PF15397.6 KEG12966.1 - 3.1 7.2 20.3 0.7 9.3 6.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Prominin PF05478.11 KEG12966.1 - 3.7 5.4 11.3 6 4.7 11.3 1.2 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 KEG12966.1 - 3.8 5.3 9.3 6.3 4.6 9.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 KEG12966.1 - 5.1 7.2 24.4 3.4 7.7 0.1 4.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 KEG12966.1 - 5.3 7.6 33.6 13 6.3 22.3 3.9 3 1 1 4 4 4 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 KEG12966.1 - 7.2 7.2 20.8 4.2 8.0 6.8 4.2 2 1 0 4 4 4 0 Syntaxin 6, N-terminal MPS2 PF17060.5 KEG12966.1 - 7.7 5.7 9.3 15 4.7 9.3 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 GIT_CC PF16559.5 KEG12966.1 - 9.7 6.1 25.8 0.3 11.0 8.6 3.7 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SRR1 PF07985.12 KEG12967.1 - 5.9e-05 23.0 0.3 0.00045 20.2 0.3 2.2 1 1 0 1 1 1 1 SRR1 DGF-1_C PF11040.8 KEG12967.1 - 0.23 11.5 2.1 0.75 9.8 0.5 2.3 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus MTS PF05175.14 KEG12968.1 - 0.00072 19.1 0.2 7.3 6.1 0.1 3.4 2 1 1 3 3 3 3 Methyltransferase small domain Methyltransf_23 PF13489.6 KEG12968.1 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain dCMP_cyt_deam_1 PF00383.23 KEG12969.1 - 4.6e-06 26.4 0.9 1e-05 25.3 0.9 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEG12969.1 - 0.00051 19.8 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Gp5_C PF06715.12 KEG12969.1 - 0.22 11.7 0.4 0.73 10.1 0.4 2.0 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) DUF3624 PF12292.8 KEG12970.1 - 0.16 12.4 0.1 0.39 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) DSPc PF00782.20 KEG12971.1 - 7.2e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3079 PF11278.8 KEG12972.1 - 0.051 13.4 0.9 0.36 10.7 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3079) Pkinase PF00069.25 KEG12975.1 - 2.7e-48 164.6 0.0 1.2e-47 162.5 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12975.1 - 4.8e-30 104.7 0.0 9.1e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG12975.1 - 1.3e-05 24.7 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT_EZ PF13513.6 KEG12976.1 - 1.5e-05 25.4 7.4 0.00041 20.8 0.0 5.6 6 1 1 7 7 7 1 HEAT-like repeat IBN_N PF03810.19 KEG12976.1 - 0.00012 21.9 0.1 0.0025 17.7 0.1 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain TAF6_C PF07571.13 KEG12976.1 - 0.00016 21.9 0.0 0.89 9.9 0.0 4.5 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 KEG12976.1 - 0.001 19.1 9.3 2.3 8.7 0.0 7.3 7 0 0 7 7 7 1 HEAT repeat FANCI_S2 PF14676.6 KEG12976.1 - 0.023 15.0 0.1 0.52 10.6 0.0 2.9 2 0 0 2 2 2 0 FANCI solenoid 2 UME PF08064.13 KEG12976.1 - 0.036 14.0 0.3 1.7 8.6 0.0 3.5 3 1 1 4 4 4 0 UME (NUC010) domain RTP1_C1 PF10363.9 KEG12976.1 - 0.037 14.2 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KEG12976.1 - 0.05 13.1 0.2 0.87 9.1 0.0 2.7 2 1 1 3 3 3 0 Tti2 family TFCD_C PF12612.8 KEG12976.1 - 0.064 13.1 0.7 17 5.2 0.1 3.1 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 KEG12976.1 - 0.13 12.9 0.2 9.4 6.9 0.0 3.9 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Vps51 PF08700.11 KEG12977.1 - 0.052 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Vps51/Vps67 Syntaxin PF00804.25 KEG12977.1 - 0.19 11.4 7.1 0.077 12.7 3.8 2.1 2 1 0 2 2 2 0 Syntaxin CAF1 PF04857.20 KEG12978.1 - 2.9e-54 184.4 0.0 4.4e-54 183.8 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KEG12978.1 - 0.089 12.5 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 3'-5' exonuclease Peptidase_M24 PF00557.24 KEG12979.1 - 7.4e-52 176.1 0.0 1.3e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEG12979.1 - 1e-23 83.4 0.0 2.8e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 KEG12979.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF1764 PF08576.10 KEG12980.1 - 1.1e-07 32.7 12.8 4.3e-07 30.8 4.5 2.3 1 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) SET PF00856.28 KEG12981.1 - 0.00011 22.7 0.0 0.0087 16.5 0.0 2.9 1 1 0 1 1 1 1 SET domain zf-RanBP PF00641.18 KEG12981.1 - 0.12 11.7 2.4 1 8.8 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Rubredoxin_2 PF18073.1 KEG12981.1 - 1.2 8.9 6.5 0.086 12.6 1.2 1.9 2 0 0 2 2 2 0 Rubredoxin metal binding domain Spt4 PF06093.13 KEG12983.1 - 4.4e-12 45.9 0.0 7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF2072 PF09845.9 KEG12983.1 - 0.3 11.4 2.6 4.5 7.5 0.4 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein Sigma70_ner PF04546.13 KEG12983.1 - 0.33 10.8 6.4 0.38 10.6 6.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Astro_capsid_p PF12226.8 KEG12983.1 - 1.5 7.9 9.7 1.8 7.6 9.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Spt5_N PF11942.8 KEG12983.1 - 2.3 9.3 15.4 3.8 8.6 15.4 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.9 KEG12983.1 - 3.6 6.6 17.0 4.6 6.3 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KEG12983.1 - 5.3 5.2 6.8 6.4 4.9 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 KEG12983.1 - 6.8 5.6 11.4 8.5 5.3 11.4 1.1 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 KEG12983.1 - 8.1 4.5 9.8 9.6 4.3 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KEG12983.1 - 9.4 4.2 14.8 11 3.9 14.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 KEG12985.1 - 1e-12 48.3 6.5 4.9e-06 27.2 0.9 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG12985.1 - 0.17 12.2 0.0 8.5 6.8 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 KEG12986.1 - 6.8e-150 499.9 2.0 7.8e-150 499.7 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 KEG12986.1 - 0.035 14.2 0.2 0.13 12.3 0.2 2.0 1 0 0 1 1 1 0 Resolvase, N terminal domain Y_phosphatase2 PF03162.13 KEG12987.1 - 2.4e-22 79.3 0.0 1.2e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Pkinase PF00069.25 KEG12988.1 - 3.3e-37 128.3 0.1 1.4e-30 106.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG12988.1 - 6.2e-18 65.0 0.2 1.1e-17 64.2 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG12988.1 - 0.0028 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Maf PF02545.14 KEG12989.1 - 1.8e-23 83.2 0.0 2e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF4012 PF13196.6 KEG12989.1 - 0.15 12.5 0.1 15 6.1 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4012) Herpes_UL6 PF01763.16 KEG12990.1 - 0.0026 16.4 2.2 0.0026 16.4 2.2 2.7 2 1 2 4 4 4 1 Herpesvirus UL6 like Fez1 PF06818.15 KEG12990.1 - 0.0038 17.7 6.8 0.0038 17.7 6.8 3.2 2 1 1 3 3 3 1 Fez1 UPF0242 PF06785.11 KEG12990.1 - 0.0096 16.0 12.2 0.0096 16.0 12.2 3.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KEG12990.1 - 0.013 15.8 14.1 0.013 15.8 14.1 4.0 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Aft1_OSA PF11785.8 KEG12990.1 - 0.062 13.7 0.2 0.21 12.1 0.2 1.9 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Pox_A_type_inc PF04508.12 KEG12990.1 - 0.11 12.3 1.9 2 8.4 0.7 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1539 PF07560.11 KEG12990.1 - 0.36 10.9 4.6 0.41 10.7 1.9 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) PMC2NT PF08066.12 KEG12990.1 - 0.86 10.3 8.6 0.42 11.3 2.6 3.2 2 1 0 2 2 2 0 PMC2NT (NUC016) domain FliD_N PF02465.18 KEG12990.1 - 1.3 9.8 9.1 26 5.6 0.5 4.1 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Metallophos_2 PF12850.7 KEG12991.1 - 3.6e-17 63.0 0.2 4.4e-17 62.8 0.2 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KEG12991.1 - 0.026 15.0 0.3 2.6 8.5 0.0 2.2 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase WD40 PF00400.32 KEG12992.1 - 4.3e-06 27.3 7.5 0.17 12.8 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG12992.1 - 0.024 14.9 0.0 2.6 8.4 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 KEG12993.1 - 1.4e-16 60.0 0.0 1.5e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain HECT PF00632.25 KEG12995.1 - 2.1e-71 240.9 0.0 3.4e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CIAPIN1 PF05093.13 KEG12995.1 - 0.028 14.9 3.0 0.19 12.2 2.9 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ZZ PF00569.17 KEG12995.1 - 0.051 13.4 9.9 0.11 12.3 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Arm PF00514.23 KEG12995.1 - 0.072 13.2 0.4 6.1 7.0 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat zf-MYND PF01753.18 KEG12995.1 - 0.5 10.5 9.4 1.4 9.1 9.4 1.8 1 0 0 1 1 1 0 MYND finger CRM1_C PF08767.11 KEG12996.1 - 2.3e-60 204.5 3.5 8.8e-60 202.5 0.1 3.1 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 KEG12996.1 - 4e-27 95.1 0.9 4e-27 95.1 0.9 4.3 6 0 0 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KEG12996.1 - 8e-25 86.3 0.8 8e-25 86.3 0.8 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KEG12996.1 - 3.6e-21 75.0 1.5 9.8e-21 73.6 0.8 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 KEG12996.1 - 7e-10 38.7 0.0 2.9e-09 36.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 KEG12996.1 - 1.4e-09 37.3 0.7 3.5e-09 36.0 0.7 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Mito_carr PF00153.27 KEG12997.1 - 2.4e-45 152.4 1.4 4.1e-16 58.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KEG12998.1 - 1.7e-52 175.3 1.7 2e-18 66.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 60KD_IMP PF02096.20 KEG12998.1 - 0.033 14.1 0.0 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 60Kd inner membrane protein Yip1 PF04893.17 KEG12998.1 - 0.034 13.9 0.5 0.048 13.4 0.5 1.3 1 0 0 1 1 1 0 Yip1 domain Kinesin PF00225.23 KEG13000.1 - 1e-59 202.1 0.0 1.8e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG13000.1 - 4.5e-10 39.6 0.0 9.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KEG13000.1 - 0.0036 17.7 0.0 0.0077 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEG13000.1 - 0.023 15.0 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEG13000.1 - 0.039 14.3 1.8 0.88 9.9 1.8 2.2 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 KEG13000.1 - 0.16 11.6 0.1 19 4.8 0.1 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF87 PF01935.17 KEG13000.1 - 0.22 11.6 0.6 0.57 10.2 0.3 1.8 1 1 1 2 2 2 0 Helicase HerA, central domain HSP70 PF00012.20 KEG13001.1 - 1.3e-68 231.7 0.2 1.9e-68 231.2 0.2 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEG13001.1 - 0.024 13.4 0.0 0.058 12.2 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein MEIOC PF15189.6 KEG13001.1 - 0.079 12.6 0.4 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC CdiA_C_tRNase PF18664.1 KEG13001.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain Thiolase_C PF02803.18 KEG13001.1 - 0.15 11.7 0.1 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 Thiolase, C-terminal domain GCV_H PF01597.19 KEG13002.1 - 7e-38 129.3 0.5 8e-38 129.1 0.5 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KEG13002.1 - 2.4e-06 27.3 2.5 5.4e-06 26.2 1.8 1.9 1 1 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 KEG13002.1 - 0.0009 19.2 1.0 0.0017 18.3 0.7 1.6 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 KEG13002.1 - 0.03 14.1 0.3 0.075 12.8 0.2 1.7 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 TTRAP PF14203.6 KEG13003.1 - 0.16 12.0 0.3 0.16 12.0 0.3 3.2 3 1 1 4 4 4 0 Putative tranposon-transfer assisting protein DASH_Dam1 PF08653.10 KEG13003.1 - 0.16 11.8 1.8 2.8 7.8 0.3 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Fe-ADH PF00465.19 KEG13003.1 - 0.16 10.7 1.3 0.23 10.2 1.3 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase APG6_N PF17675.1 KEG13003.1 - 0.41 11.2 35.0 94 3.5 35.0 2.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3552 PF12072.8 KEG13003.1 - 0.46 9.9 34.5 4.7 6.6 0.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KEG13003.1 - 0.54 9.1 30.2 0.021 13.7 15.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KEG13003.1 - 2.1 8.5 33.2 1.6 8.9 27.4 2.8 1 1 1 2 2 2 0 Tropomyosin like CDC37_N PF03234.14 KEG13003.1 - 2.6 9.0 13.7 19 6.2 13.7 2.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding AAA_23 PF13476.6 KEG13003.1 - 3 8.3 16.8 4.1 7.8 16.8 1.2 1 0 0 1 1 1 0 AAA domain Plk4_PB2 PF18409.1 KEG13003.1 - 8.1 7.2 7.9 17 6.1 4.0 2.6 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Gp_dh_C PF02800.20 KEG13005.1 - 2.9e-24 85.4 0.0 4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KEG13005.1 - 5e-19 68.5 0.1 8.3e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pro_isomerase PF00160.21 KEG13007.1 - 8.3e-47 159.4 0.1 1.4e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KEG13007.1 - 2.1e-11 43.0 3.2 0.0018 18.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13007.1 - 4.3e-09 35.8 1.8 0.0029 17.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13007.1 - 0.0004 21.0 2.9 0.0004 21.0 2.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13007.1 - 0.0025 17.9 1.3 0.19 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13007.1 - 0.0035 17.5 3.7 0.0072 16.5 3.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13007.1 - 0.0047 17.6 4.6 0.098 13.5 1.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13007.1 - 0.0059 16.3 7.5 1.2 8.9 0.3 3.4 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 KEG13007.1 - 0.014 15.7 1.5 0.014 15.7 1.5 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13007.1 - 0.068 13.4 2.7 0.15 12.3 1.7 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEG13007.1 - 0.086 13.3 1.2 4 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG13007.1 - 0.11 12.5 1.0 0.84 9.8 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KEG13007.1 - 0.25 11.9 6.6 3.7 8.1 1.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG13007.1 - 1.8 9.4 8.7 6.6 7.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SCAMP PF04144.13 KEG13009.1 - 1.8e-40 139.1 11.1 2.2e-40 138.8 11.1 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.11 KEG13009.1 - 0.00097 18.7 0.1 0.00097 18.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) A_deaminase PF00962.22 KEG13010.1 - 8.8e-122 406.5 0.0 2.5e-86 290.0 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase BAR PF03114.18 KEG13010.1 - 0.039 13.6 1.6 0.32 10.6 2.3 2.0 2 0 0 2 2 2 0 BAR domain LPP PF04728.13 KEG13010.1 - 0.13 12.7 4.2 0.13 12.7 1.9 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper BRCT_2 PF16589.5 KEG13011.1 - 0.00012 22.4 0.0 0.0071 16.7 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KEG13011.1 - 0.0086 16.3 0.0 0.043 14.1 0.0 2.2 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KEG13011.1 - 0.032 14.6 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Zn_ribbon_17 PF17120.5 KEG13011.1 - 0.53 10.0 5.3 1.3 8.7 5.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PSP PF04046.16 KEG13011.1 - 0.89 9.5 2.4 1.9 8.4 1.0 2.2 3 0 0 3 3 3 0 PSP PRKCSH PF07915.13 KEG13012.1 - 8.8e-10 39.5 0.0 1.5e-09 38.7 0.0 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KEG13012.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein His_Phos_1 PF00300.22 KEG13013.1 - 5.2e-08 32.8 0.0 0.0014 18.4 0.0 3.2 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) DUF2267 PF10025.9 KEG13014.1 - 0.033 14.5 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) E3_UbLigase_EDD PF11547.8 KEG13014.1 - 0.14 11.9 0.2 0.32 10.7 0.2 1.5 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Proteasome PF00227.26 KEG13016.1 - 1.4e-36 125.8 0.0 1.9e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG13016.1 - 6.8e-12 44.8 0.2 1.5e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FAM184 PF15665.5 KEG13018.1 - 8.5e-06 25.7 94.2 4.2e-05 23.4 38.0 4.7 1 1 2 3 3 3 1 Family with sequence similarity 184, A and B FliJ PF02050.16 KEG13018.1 - 0.00065 19.9 20.8 0.00065 19.9 20.8 6.0 1 1 6 7 7 7 2 Flagellar FliJ protein PKK PF12474.8 KEG13018.1 - 0.0021 18.2 14.3 0.0021 18.2 14.3 6.1 1 1 4 6 6 6 1 Polo kinase kinase Tup_N PF08581.10 KEG13018.1 - 0.0039 17.4 7.5 0.0039 17.4 7.5 7.5 2 2 6 8 8 8 1 Tup N-terminal DUF1664 PF07889.12 KEG13018.1 - 0.0086 16.1 1.9 0.0086 16.1 1.9 6.4 2 2 4 6 6 6 2 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 KEG13018.1 - 0.012 15.8 14.3 0.012 15.8 14.3 6.0 2 2 3 6 6 6 0 Cortexillin I, coiled coil DUF4200 PF13863.6 KEG13018.1 - 0.015 15.7 16.3 0.015 15.7 16.3 5.8 1 1 4 5 5 5 0 Domain of unknown function (DUF4200) Filament PF00038.21 KEG13018.1 - 0.017 14.7 83.6 0.013 15.1 47.8 3.5 1 1 1 2 2 2 0 Intermediate filament protein SHE3 PF17078.5 KEG13018.1 - 4.6 6.9 64.2 0.16 11.6 12.9 5.2 1 1 4 5 5 5 0 SWI5-dependent HO expression protein 3 zf-ZPR1 PF03367.13 KEG13018.1 - 4.8 7.0 31.4 0.28 11.0 4.8 4.5 3 1 2 5 5 5 0 ZPR1 zinc-finger domain Nup192 PF11894.8 KEG13020.1 - 4.2e-11 40.8 9.2 1.4e-07 29.2 4.7 3.1 3 0 0 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 Med15_fungi PF05397.12 KEG13020.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 15 DUF1664 PF07889.12 KEG13022.1 - 0.025 14.6 3.4 0.025 14.6 3.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Herpes_UL16 PF03044.14 KEG13022.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Atg14 PF10186.9 KEG13022.1 - 3.4 6.7 21.7 34 3.4 21.7 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VPS13 PF16908.5 KEG13024.1 - 4e-35 121.7 0.0 1.8e-33 116.3 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 KEG13024.1 - 7.1e-29 100.3 0.5 1.4e-27 96.1 0.1 3.2 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KEG13024.1 - 1.5e-25 90.1 0.0 2.4e-23 82.9 0.0 2.4 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 SUIM_assoc PF16619.5 KEG13024.1 - 0.61 10.2 4.0 1.8 8.7 4.0 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 EAP30 PF04157.16 KEG13025.1 - 1.4e-58 198.0 0.0 1.7e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 KEG13025.1 - 0.063 13.2 0.1 0.51 10.3 0.0 2.5 3 0 0 3 3 3 0 MarR family 2-Hacid_dh_C PF02826.19 KEG13026.1 - 4.1e-47 159.8 0.0 5.4e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KEG13026.1 - 0.00053 20.2 0.1 0.00079 19.6 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KEG13026.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KEG13026.1 - 0.0077 16.8 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KEG13026.1 - 0.0082 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEG13026.1 - 0.018 15.3 0.2 0.11 12.7 0.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KEG13026.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 KEG13026.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.21 KEG13026.1 - 0.19 11.8 0.1 0.41 10.7 0.1 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4315 PF14193.6 KEG13027.1 - 0.0049 16.8 8.2 0.29 11.2 2.8 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4315) TMPIT PF07851.13 KEG13027.1 - 0.3 10.3 5.4 0.91 8.7 5.4 1.8 1 0 0 1 1 1 0 TMPIT-like protein Sec34 PF04136.15 KEG13027.1 - 3.5 7.5 8.4 1 9.2 1.3 3.3 3 1 1 4 4 4 0 Sec34-like family DUF1664 PF07889.12 KEG13027.1 - 9 6.4 9.2 1.8 8.6 3.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Methyltransf_PK PF05891.12 KEG13028.1 - 1.1e-62 211.4 0.0 1.3e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 KEG13028.1 - 4.1e-11 43.4 0.0 7.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG13028.1 - 5.9e-11 42.9 0.0 1.6e-10 41.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG13028.1 - 2e-06 27.8 0.0 3.6e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG13028.1 - 4.5e-06 27.3 0.0 8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG13028.1 - 7.1e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KEG13028.1 - 0.0015 18.2 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KEG13028.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEG13028.1 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Pox_I5 PF04713.12 KEG13029.1 - 0.017 15.1 1.3 0.017 15.1 1.3 2.1 1 1 1 2 2 2 0 Poxvirus protein I5 Insulin_TMD PF17870.1 KEG13029.1 - 0.96 9.6 4.1 28 4.9 0.0 2.9 2 1 1 3 3 3 0 Insulin receptor trans-membrane segment Caveolin PF01146.17 KEG13029.1 - 3.9 7.4 6.7 0.35 10.8 2.2 1.6 2 0 0 2 2 2 0 Caveolin PilX_N PF14341.6 KEG13030.1 - 0.042 13.8 2.3 0.042 13.8 2.3 2.0 2 0 0 2 2 2 0 PilX N-terminal Pkinase PF00069.25 KEG13031.1 - 3.1e-69 233.3 0.0 4.1e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13031.1 - 3e-29 102.1 0.0 4.1e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG13031.1 - 4.3e-11 43.3 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KEG13031.1 - 0.00048 19.5 0.1 0.0092 15.3 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KEG13031.1 - 0.018 15.8 0.2 0.018 15.8 0.2 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain DUF1754 PF08555.10 KEG13032.1 - 0.0028 18.4 4.2 0.034 14.9 4.3 2.1 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Coilin_N PF15862.5 KEG13032.1 - 0.0044 16.8 0.4 0.0044 16.8 0.4 2.3 1 1 1 2 2 2 1 Coilin N-terminus PDGF_N PF04692.13 KEG13032.1 - 0.023 15.5 19.2 0.3 11.9 6.0 2.6 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region SUIM_assoc PF16619.5 KEG13032.1 - 0.28 11.3 19.3 0.11 12.5 1.8 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2828 PF11443.8 KEG13032.1 - 0.42 8.6 6.8 0.59 8.2 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Otopetrin PF03189.13 KEG13032.1 - 0.54 9.0 2.9 0.69 8.7 2.9 1.1 1 0 0 1 1 1 0 Otopetrin baeRF_family8 PF18851.1 KEG13032.1 - 1.4 8.9 8.2 10 6.2 2.0 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 SLC12 PF03522.15 KEG13032.1 - 3.4 6.6 8.2 4.6 6.2 8.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Suf PF05843.14 KEG13032.1 - 3.4 7.6 11.2 6.2 6.7 11.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TMEM214 PF10151.9 KEG13032.1 - 3.5 6.0 5.9 5 5.5 5.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Presenilin PF01080.17 KEG13032.1 - 4.8 5.8 9.2 6.8 5.3 9.2 1.2 1 0 0 1 1 1 0 Presenilin MgtE_N PF03448.17 KEG13033.1 - 0.088 13.4 0.4 4.1 8.1 0.0 3.0 2 0 0 2 2 2 0 MgtE intracellular N domain AlbA_2 PF04326.14 KEG13035.1 - 0.048 14.0 0.0 0.084 13.2 0.0 1.5 1 1 0 1 1 1 0 Putative DNA-binding domain Arm PF00514.23 KEG13036.1 - 2.1e-19 68.8 17.7 0.016 15.3 0.0 12.4 14 0 0 14 14 14 7 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KEG13036.1 - 5.6e-16 58.4 13.6 0.0083 16.1 0.1 7.7 2 2 6 8 8 8 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 KEG13036.1 - 8.2e-10 38.9 3.6 0.23 11.9 0.0 7.0 4 2 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 KEG13036.1 - 0.0015 19.0 14.8 0.026 15.0 0.3 6.9 6 1 2 8 8 8 1 HEAT-like repeat FliG_N PF14842.6 KEG13036.1 - 0.022 15.3 0.1 0.53 10.9 0.0 3.0 2 0 0 2 2 2 0 FliG N-terminal domain DUF3361 PF11841.8 KEG13036.1 - 0.082 12.9 6.8 1.6 8.7 0.4 4.1 2 2 0 2 2 2 0 Domain of unknown function (DUF3361) HEAT PF02985.22 KEG13036.1 - 0.16 12.3 9.8 86 3.8 0.0 7.5 8 0 0 8 8 8 0 HEAT repeat UME PF08064.13 KEG13036.1 - 0.92 9.5 6.3 2.5 8.0 0.1 4.3 6 0 0 6 6 6 0 UME (NUC010) domain Lactamase_B PF00753.27 KEG13037.1 - 1.6e-09 38.1 0.1 5.6e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEG13037.1 - 0.05 13.1 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DJ-1_PfpI PF01965.24 KEG13038.1 - 1.6e-38 132.1 0.2 2e-38 131.8 0.2 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_15 PF13429.6 KEG13039.1 - 0.0026 17.0 1.3 0.0038 16.5 1.3 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat APG6_N PF17675.1 KEG13040.1 - 0.0037 17.8 13.6 0.0037 17.8 13.6 3.4 2 1 2 4 4 4 1 Apg6 coiled-coil region IFT57 PF10498.9 KEG13040.1 - 0.0047 16.0 9.9 0.0047 16.0 9.9 2.7 2 1 0 2 2 2 1 Intra-flagellar transport protein 57 GAS PF13851.6 KEG13040.1 - 0.31 10.4 41.4 0.88 8.9 10.5 4.8 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KEG13040.1 - 0.36 11.0 24.9 0.82 9.8 7.7 4.4 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 KEG13040.1 - 0.6 9.4 17.6 1.6 8.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF99 PF01949.16 KEG13040.1 - 0.75 9.2 4.0 2.8 7.3 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF99 GIT_CC PF16559.5 KEG13040.1 - 2.8 7.9 17.0 5.5 6.9 0.2 5.0 2 2 3 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 KEG13040.1 - 4.1 7.4 10.2 1.1 9.3 2.9 3.1 2 1 1 3 3 3 0 FlxA-like protein Atg14 PF10186.9 KEG13040.1 - 9.3 5.2 22.6 0.13 11.3 7.9 2.8 2 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kinesin PF00225.23 KEG13042.1 - 2.8e-82 276.3 0.0 1e-81 274.5 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG13042.1 - 3.9e-17 62.6 0.0 1.3e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding MMR_HSR1 PF01926.23 KEG13042.1 - 0.0059 16.7 0.3 0.46 10.6 0.0 3.8 4 0 0 4 4 4 1 50S ribosome-binding GTPase DUF3772 PF12607.8 KEG13042.1 - 0.12 12.2 1.3 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Radical_SAM_C PF16199.5 KEG13042.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Radical_SAM C-terminal domain AAA_16 PF13191.6 KEG13042.1 - 0.46 10.9 3.5 12 6.3 0.0 3.8 3 1 0 3 3 3 0 AAA ATPase domain GrpE PF01025.19 KEG13043.1 - 8.4e-39 132.9 1.9 1e-38 132.6 1.9 1.1 1 0 0 1 1 1 1 GrpE I_LWEQ PF01608.17 KEG13043.1 - 0.0075 16.5 0.6 0.012 15.9 0.6 1.3 1 0 0 1 1 1 1 I/LWEQ domain Met_gamma_lyase PF06838.11 KEG13043.1 - 0.023 13.2 0.1 0.03 12.9 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Sugar_tr PF00083.24 KEG13045.1 - 6.4e-20 71.4 6.6 7.3e-20 71.2 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KEG13046.1 - 8.2e-43 146.9 13.1 9.4e-43 146.7 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEG13046.1 - 0.0001 21.4 10.7 0.00013 21.0 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2970 PF11174.8 KEG13046.1 - 0.052 13.4 0.5 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DnaJ_C PF01556.18 KEG13047.1 - 7.2e-34 117.0 0.0 9.4e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG13047.1 - 1.4e-27 95.6 1.7 2.6e-27 94.7 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain Ras PF00071.22 KEG13048.1 - 6.3e-48 162.4 0.2 8.2e-48 162.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG13048.1 - 1.8e-32 112.1 0.1 2.6e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG13048.1 - 5.6e-08 32.4 0.0 6.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG13048.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KEG13048.1 - 0.0072 16.1 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KEG13048.1 - 0.014 14.9 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KEG13048.1 - 0.015 14.7 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEG13048.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KEG13048.1 - 0.037 13.9 0.3 2.1 8.3 0.0 2.5 1 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 KEG13048.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KEG13049.1 - 0.016 15.4 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KEG13049.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KEG13050.1 - 9.2e-66 220.6 0.2 1.1e-65 220.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG13050.1 - 4.4e-14 52.7 0.0 6.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEG13050.1 - 2.3e-12 46.8 0.0 2.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEG13050.1 - 1.3e-11 44.3 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEG13050.1 - 4.8e-11 42.4 0.0 6.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEG13050.1 - 1.8e-10 40.6 0.4 5.4e-08 32.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KEG13050.1 - 1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KEG13050.1 - 0.0014 18.1 0.0 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein GTP_EFTU PF00009.27 KEG13050.1 - 0.0017 18.0 0.4 0.09 12.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain BPL_N PF09825.9 KEG13051.1 - 4.1 6.4 9.8 0.065 12.3 0.5 2.3 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Fe-ADH PF00465.19 KEG13052.1 - 4.5e-58 196.8 0.4 5.3e-58 196.6 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KEG13052.1 - 2.6e-27 96.1 0.0 3.7e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 KEG13052.1 - 0.0018 17.5 0.3 0.034 13.3 0.3 2.5 1 1 0 1 1 1 1 3-dehydroquinate synthase Vps54 PF07928.12 KEG13053.1 - 1.1e-23 84.2 0.0 2.3e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Vps54-like protein COG2 PF06148.11 KEG13053.1 - 0.0046 17.0 0.7 0.014 15.5 0.2 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 3HCDH PF00725.22 KEG13054.1 - 2.4e-09 37.7 0.1 7.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 KEG13054.1 - 0.00021 20.7 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Cas9_Topo PF17894.1 KEG13054.1 - 0.16 12.1 0.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Suc_Fer-like PF06999.12 KEG13056.1 - 1.1e-25 90.7 0.0 2e-25 89.8 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Kelch_1 PF01344.25 KEG13057.1 - 1e-24 85.8 0.1 9.5e-05 21.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KEG13057.1 - 6.6e-24 83.7 0.2 1.4e-06 28.4 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG13057.1 - 4.6e-21 74.4 0.3 0.0003 20.7 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KEG13057.1 - 3.9e-18 64.6 3.3 5.5e-05 23.0 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KEG13057.1 - 1.4e-16 60.1 0.2 0.0047 17.2 0.0 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KEG13057.1 - 1.9e-14 53.4 1.8 0.0045 17.0 0.1 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Ran_BP1 PF00638.18 KEG13058.1 - 0.00085 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KEG13058.1 - 0.0041 17.7 3.5 0.0041 17.7 3.5 3.2 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Utp14 PF04615.13 KEG13058.1 - 0.046 12.3 0.6 0.055 12.0 0.6 1.2 1 0 0 1 1 1 0 Utp14 protein Fis1_TPR_C PF14853.6 KEG13059.1 - 1.5e-12 47.4 1.9 1.5e-11 44.1 0.5 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KEG13059.1 - 0.00063 19.7 2.5 0.0013 18.7 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat HhH-GPD PF00730.25 KEG13059.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein TPR_1 PF00515.28 KEG13059.1 - 0.039 13.8 0.2 0.087 12.7 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG13059.1 - 0.043 14.3 0.0 48 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13059.1 - 0.14 13.1 1.1 5.8 8.0 0.1 3.3 3 1 2 5 5 5 0 Tetratricopeptide repeat CK2S PF15011.6 KEG13062.1 - 0.0022 17.9 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 Casein Kinase 2 substrate zf_C2HC_14 PF18574.1 KEG13062.1 - 0.0043 16.8 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 C2HC Zing finger domain zf-Di19 PF05605.12 KEG13062.1 - 0.022 15.0 0.3 0.044 14.1 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KEG13062.1 - 0.3 12.0 1.0 0.49 11.4 0.2 1.8 1 1 0 1 1 1 0 C2H2-type zinc finger ATP_bind_3 PF01171.20 KEG13063.1 - 8.5e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KEG13063.1 - 7.1e-12 44.6 2.1 7.1e-12 44.6 2.1 3.3 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KEG13063.1 - 0.035 12.9 0.0 0.059 12.1 0.0 1.3 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 KEG13063.1 - 0.065 13.3 0.0 0.18 11.8 0.0 1.8 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Cullin PF00888.22 KEG13068.1 - 2e-55 188.6 0.0 1.3e-54 185.9 0.0 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KEG13068.1 - 1.8e-13 50.3 0.0 4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Dynein_light PF01221.18 KEG13069.1 - 1e-34 118.7 0.2 1.1e-34 118.6 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HhH-GPD PF00730.25 KEG13071.1 - 7.5e-17 61.7 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KEG13071.1 - 7.3e-09 35.6 0.0 2.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KEG13071.1 - 4.7e-06 26.2 0.0 1.8e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif Whib PF02467.16 KEG13071.1 - 0.057 14.0 1.0 0.19 12.3 0.2 2.3 2 0 0 2 2 2 0 Transcription factor WhiB Transposase_20 PF02371.16 KEG13071.1 - 0.13 12.6 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family HHH_5 PF14520.6 KEG13071.1 - 0.14 12.8 0.0 3.7 8.2 0.0 2.6 2 1 0 2 2 2 0 Helix-hairpin-helix domain S6PP_C PF08472.10 KEG13071.1 - 0.23 11.3 1.3 1.1 9.1 0.3 2.1 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal EndIII_4Fe-2S PF10576.9 KEG13071.1 - 0.97 9.9 4.8 0.23 11.9 1.0 2.0 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Kelch_3 PF13415.6 KEG13072.1 - 6e-12 45.5 4.4 2.4e-05 24.5 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KEG13072.1 - 3.3e-11 43.1 0.2 1.5e-06 28.3 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KEG13072.1 - 1.6e-10 40.7 0.9 1.2e-07 31.5 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 KEG13072.1 - 1.9e-10 40.5 3.8 1.3e-08 34.7 0.0 4.8 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG13072.1 - 7.6e-09 35.0 2.6 0.00031 20.3 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KEG13072.1 - 7.6e-06 25.7 0.4 0.00038 20.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Phage_holin_3_2 PF04550.12 KEG13072.1 - 0.17 12.4 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage holin family 2 Methyltransf_31 PF13847.6 KEG13073.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG13073.1 - 1.3e-07 32.2 0.0 2.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG13073.1 - 3.3e-06 27.6 0.0 7.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEG13073.1 - 0.00014 21.4 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KEG13073.1 - 0.00036 21.2 0.0 0.00056 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEG13073.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KEG13073.1 - 0.0072 16.1 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KEG13073.1 - 0.023 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KEG13073.1 - 0.032 13.8 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KEG13073.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 AAA_22 PF13401.6 KEG13074.1 - 0.068 13.4 0.5 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MDM31_MDM32 PF08118.11 KEG13074.1 - 0.33 9.6 3.5 0.48 9.0 3.5 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Sel1 PF08238.12 KEG13074.1 - 0.64 10.8 8.4 7.3 7.4 0.2 3.9 4 0 0 4 4 4 0 Sel1 repeat AAA_16 PF13191.6 KEG13074.1 - 5.2 7.4 6.3 19 5.6 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain HSL_N PF06350.12 KEG13075.1 - 0.0079 15.2 0.3 0.77 8.7 0.0 2.1 2 0 0 2 2 2 2 Hormone-sensitive lipase (HSL) N-terminus FXMRP1_C_core PF12235.8 KEG13075.1 - 0.14 12.8 1.9 0.25 12.0 1.9 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal NST1 PF13945.6 KEG13075.1 - 0.39 10.8 2.1 0.62 10.1 2.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator 4HBT_2 PF13279.6 KEG13076.1 - 2.7e-10 40.8 0.0 3e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 KEG13076.1 - 3.6e-06 27.2 0.4 1.1e-05 25.7 0.2 1.9 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KEG13076.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase Glyco_trans_1_4 PF13692.6 KEG13077.1 - 3.5e-12 46.9 0.0 7.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEG13077.1 - 2e-11 43.8 0.0 3.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEG13077.1 - 0.00011 22.5 0.0 0.0042 17.4 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 ATG16 PF08614.11 KEG13078.1 - 0.009 16.3 0.9 0.009 16.3 0.9 2.5 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) MitMem_reg PF13012.6 KEG13078.1 - 0.14 12.6 0.1 2.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function CENP-H PF05837.12 KEG13078.1 - 1.8 9.0 6.0 4.5 7.7 0.5 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Glyco_hydro_63 PF03200.16 KEG13080.1 - 9.6e-50 169.7 0.0 3.6e-34 118.4 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KEG13080.1 - 3.9e-15 56.6 1.4 7e-14 52.5 1.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain ANAPC4_WD40 PF12894.7 KEG13083.1 - 0.062 13.6 0.0 0.14 12.5 0.0 1.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEG13083.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 KEG13084.1 - 3.1e-54 184.1 0.0 3.8e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13084.1 - 4.8e-34 117.8 0.0 6.4e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG13084.1 - 5.3e-05 22.7 0.0 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KEG13084.1 - 0.0025 16.8 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG13084.1 - 0.0092 15.9 0.0 1.9 8.4 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KEG13084.1 - 0.061 12.3 0.1 0.089 11.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KEG13084.1 - 0.062 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KEG13084.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Carn_acyltransf PF00755.20 KEG13085.1 - 1.4e-174 582.1 0.0 1.6e-174 581.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FKBP_C PF00254.28 KEG13086.1 - 1e-33 115.5 0.0 2.7e-32 110.9 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 KEG13086.1 - 7.7e-14 50.6 3.1 0.00099 19.1 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13086.1 - 2.1e-10 39.9 1.3 0.00027 20.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13086.1 - 1.2e-07 31.9 5.4 0.051 14.4 2.2 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG13086.1 - 1.4e-07 31.5 2.5 0.0094 16.0 0.1 2.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KEG13086.1 - 2.3e-06 28.0 4.5 5.1e-06 26.9 2.6 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13086.1 - 8.6e-06 25.6 0.3 0.0027 17.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13086.1 - 9.3e-06 25.8 2.6 0.01 16.1 0.7 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13086.1 - 7.5e-05 23.3 7.1 0.65 10.7 0.4 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13086.1 - 0.00025 21.1 1.7 0.00025 21.1 1.7 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KEG13086.1 - 0.00025 21.1 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 BDBT FKBP like N-terminal TPR_7 PF13176.6 KEG13086.1 - 0.00029 20.7 4.2 2.8 8.2 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG13086.1 - 0.0069 16.7 1.6 0.42 11.1 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13086.1 - 0.021 15.0 2.1 0.034 14.4 1.1 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.13 KEG13086.1 - 0.036 14.3 0.4 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.6 KEG13086.1 - 0.045 14.4 0.4 0.045 14.4 0.4 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13086.1 - 0.12 12.1 0.5 5.8 6.7 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_10 PF13374.6 KEG13086.1 - 2.2 8.3 3.9 18 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat IF3_N PF05198.16 KEG13087.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain V_ATPase_prox PF18274.1 KEG13087.1 - 0.073 13.0 0.2 0.85 9.6 0.0 2.7 2 0 0 2 2 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe DUF4604 PF15377.6 KEG13087.1 - 6.6 7.1 6.9 0.83 10.1 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TPT PF03151.16 KEG13088.1 - 2.6e-25 89.3 17.7 3.2e-25 89.0 17.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEG13088.1 - 1.2e-10 41.7 29.4 2.1e-09 37.7 9.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family IF4E PF01652.18 KEG13090.1 - 1.7e-36 125.4 0.0 2.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 KEG13091.1 - 1.1e-45 156.0 0.0 1.2e-41 142.8 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13091.1 - 5.1e-24 85.0 0.0 1.7e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG13091.1 - 1.8e-05 23.7 0.0 2.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG13091.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEG13091.1 - 0.26 10.2 0.0 0.37 9.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain NAD_binding_1 PF00175.21 KEG13094.1 - 5.6e-11 43.0 0.0 1.6e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 KEG13094.1 - 0.0028 17.3 0.0 0.045 13.3 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 KEG13094.1 - 0.013 15.7 0.0 0.13 12.4 0.0 2.3 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Poxvirus_B22R_C PF13168.6 KEG13094.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Pkinase PF00069.25 KEG13095.1 - 3.2e-65 220.1 0.0 3.9e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13095.1 - 6.4e-32 110.9 0.0 8.7e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG13095.1 - 3.9e-07 29.7 0.0 2.2e-06 27.2 0.0 2.1 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 KEG13095.1 - 0.0028 17.0 0.3 0.0049 16.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEG13095.1 - 0.0052 16.7 0.4 0.0088 16.0 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG13095.1 - 0.008 15.2 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PIH1 PF08190.12 KEG13096.1 - 5.5e-12 45.5 0.1 1.3e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KEG13096.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain P22_Tail-4 PF11650.8 KEG13096.1 - 0.065 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor MbeB_N PF04837.12 KEG13096.1 - 0.074 13.4 2.8 0.16 12.3 2.8 1.6 1 0 0 1 1 1 0 MbeB-like, N-term conserved region RNase_H PF00075.24 KEG13099.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 RNase H ArfGap PF01412.18 KEG13101.1 - 2.8e-30 104.8 0.1 5.5e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 KEG13101.1 - 0.11 12.0 2.2 0.19 11.3 2.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4314 PF14192.6 KEG13102.1 - 0.16 11.9 0.0 0.8 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) Val_tRNA-synt_C PF10458.9 KEG13102.1 - 0.32 11.3 5.2 3.5 8.0 0.8 3.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Fungal_TACC PF12709.7 KEG13102.1 - 2.5 8.6 9.4 18 5.8 0.3 4.3 4 2 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins PPR_2 PF13041.6 KEG13103.1 - 9e-57 189.1 18.8 9.2e-10 38.6 0.0 13.3 8 3 6 14 14 14 11 PPR repeat family PPR_3 PF13812.6 KEG13103.1 - 1.9e-55 184.8 9.8 6.7e-13 48.5 0.0 11.7 7 4 5 12 12 12 9 Pentatricopeptide repeat domain PPR PF01535.20 KEG13103.1 - 1.2e-26 91.0 25.2 0.00052 20.1 0.0 13.3 14 1 0 14 14 14 6 PPR repeat PPR_long PF17177.4 KEG13103.1 - 2e-26 92.7 9.4 1.8e-10 40.6 0.0 6.1 4 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KEG13103.1 - 1.1e-24 85.8 21.5 4.5e-05 23.1 0.0 12.6 13 0 0 13 13 13 6 PPR repeat RPM2 PF08579.11 KEG13103.1 - 1.9e-07 31.5 0.4 1.2 9.6 0.1 6.4 4 1 1 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 KEG13103.1 - 0.0002 21.9 1.6 26 6.0 0.0 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TAP_C PF03943.13 KEG13103.1 - 0.015 14.9 0.1 0.087 12.5 0.0 2.4 2 0 0 2 2 2 0 TAP C-terminal domain ECSIT PF06239.11 KEG13103.1 - 0.024 13.8 3.3 13 4.8 0.0 5.0 2 2 1 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway DASH_Ask1 PF08655.10 KEG13103.1 - 0.16 11.9 0.0 0.51 10.3 0.0 1.9 1 0 0 1 1 1 0 DASH complex subunit Ask1 TPR_12 PF13424.6 KEG13103.1 - 2.1 8.7 5.2 26 5.2 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KEG13104.1 - 1.9e-30 105.7 0.0 3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF641 PF04859.12 KEG13105.1 - 0.053 13.9 0.5 0.053 13.9 0.5 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) SUIM_assoc PF16619.5 KEG13105.1 - 0.098 12.7 6.7 0.54 10.4 1.0 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Nbl1_Borealin_N PF10444.9 KEG13105.1 - 0.13 11.9 1.6 0.32 10.7 1.6 1.6 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Ank_2 PF12796.7 KEG13106.1 - 2.5e-11 44.0 0.1 6.2e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG13106.1 - 5.1e-11 42.6 2.7 8e-06 26.0 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEG13106.1 - 1.6e-10 40.9 10.6 1.9e-05 24.9 1.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KEG13106.1 - 4.6e-10 38.9 0.5 3.2e-05 24.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KEG13106.1 - 5.9e-09 36.3 2.0 7.8e-08 32.7 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ABC2_membrane_3 PF12698.7 KEG13107.1 - 5.6e-31 107.9 43.6 1.6e-22 80.1 16.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 KEG13107.1 - 2.2e-29 102.7 0.0 1.4e-13 51.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEG13107.1 - 5.9e-07 29.6 0.8 0.092 12.5 0.1 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEG13107.1 - 0.0003 21.2 0.0 0.00077 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEG13107.1 - 0.0062 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KEG13107.1 - 0.016 14.7 0.0 0.27 10.6 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEG13107.1 - 0.022 14.7 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF3584 PF12128.8 KEG13107.1 - 0.032 11.8 0.3 0.042 11.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.12 KEG13107.1 - 0.035 14.0 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KEG13107.1 - 0.036 14.6 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEG13107.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEG13107.1 - 0.082 12.5 0.2 0.82 9.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KEG13107.1 - 0.12 12.8 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEG13107.1 - 0.15 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEG13107.1 - 0.18 11.0 0.2 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 KEG13107.1 - 0.33 10.6 0.1 0.54 9.9 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain Cpta_toxin PF07254.12 KEG13108.1 - 0.014 15.3 0.3 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system DUF4079 PF13301.6 KEG13108.1 - 0.12 12.6 2.0 5.8 7.1 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) MORN PF02493.20 KEG13109.1 - 6.3e-20 69.8 23.4 1.7e-07 30.7 2.4 6.7 7 0 0 7 7 7 5 MORN repeat ELO PF01151.18 KEG13110.1 - 3.7e-43 147.9 19.8 4.6e-43 147.5 19.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Es2 PF09751.9 KEG13111.1 - 0.18 11.5 0.1 0.25 11.1 0.1 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 PPR_2 PF13041.6 KEG13112.1 - 4.8e-05 23.5 4.0 1.8 8.9 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 KEG13112.1 - 0.09 13.1 8.3 8.7 6.8 0.1 5.0 6 0 0 6 6 6 0 PPR repeat RRP14 PF15459.6 KEG13113.1 - 0.39 11.3 7.4 1.1 9.9 7.4 1.7 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 AP-5_subunit_s1 PF15001.6 KEG13113.1 - 0.95 9.4 5.1 3 7.8 5.1 1.8 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Trp_dioxygenase PF03301.13 KEG13114.1 - 9.4e-10 38.3 0.0 0.0006 19.2 0.0 2.0 2 0 0 2 2 2 2 Tryptophan 2,3-dioxygenase GKAP PF03359.13 KEG13115.1 - 0.014 15.0 1.2 0.023 14.3 1.2 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DnaJ PF00226.31 KEG13116.1 - 4.1e-17 62.1 0.1 6.2e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Hydrolase_4 PF12146.8 KEG13116.1 - 0.08 12.2 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ADP_PFK_GK PF04587.15 KEG13116.1 - 0.091 11.3 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Galactosyl_T PF01762.21 KEG13117.1 - 1.4e-06 28.2 0.2 5.7e-05 23.0 0.0 2.9 2 1 0 3 3 3 1 Galactosyltransferase Ribonuclease_3 PF00636.26 KEG13120.1 - 0.00011 22.7 0.0 0.00034 21.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain BILBO1_N PF18281.1 KEG13121.1 - 1.4e-26 92.7 0.1 4.2e-26 91.2 0.1 1.8 1 0 0 1 1 1 1 BILBO1 N-terminal domain EF-hand_7 PF13499.6 KEG13121.1 - 0.0015 19.0 0.0 0.0053 17.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair DUF1664 PF07889.12 KEG13121.1 - 0.37 10.8 1.5 0.9 9.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KEG13121.1 - 0.38 11.4 6.8 0.18 12.5 4.2 1.8 2 0 0 2 2 2 0 Initiation control protein YabA FAD_binding_1 PF00667.20 KEG13122.1 - 4.9e-41 140.7 0.0 8.5e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEG13122.1 - 1.2e-21 77.4 1.7 1.7e-21 76.9 0.1 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KEG13122.1 - 9.4e-16 58.4 0.0 2.5e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Smg4_UPF3 PF03467.15 KEG13124.1 - 6.3e-08 32.8 0.1 9e-07 29.1 0.1 2.5 1 1 0 1 1 1 1 Smg-4/UPF3 family HSP70 PF00012.20 KEG13127.1 - 2.4e-252 838.5 14.0 2.7e-252 838.3 14.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEG13127.1 - 2.1e-19 69.5 0.6 2.5e-16 59.4 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KEG13127.1 - 0.00012 21.8 0.0 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KEG13127.1 - 0.016 14.5 0.5 0.032 13.5 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FIVAR PF07554.13 KEG13127.1 - 0.089 13.6 1.9 0.43 11.4 1.9 2.2 1 0 0 1 1 1 0 FIVAR domain FtsA PF14450.6 KEG13127.1 - 0.26 11.7 2.3 12 6.4 0.1 3.3 3 2 0 3 3 3 0 Cell division protein FtsA DUF1542 PF07564.11 KEG13127.1 - 0.73 10.0 4.2 1.3 9.2 2.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) zf-AN1 PF01428.16 KEG13129.1 - 1.4e-07 31.5 0.4 1.9e-07 31.1 0.4 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4407 PF14362.6 KEG13129.1 - 0.062 12.7 2.7 0.067 12.5 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_C PF00137.21 KEG13130.1 - 7e-27 93.5 40.6 1.2e-18 67.2 12.7 2.8 3 0 0 3 3 3 2 ATP synthase subunit C Peptidase_M8 PF01457.16 KEG13131.1 - 2.1e-35 122.4 0.0 2.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin IBR PF01485.21 KEG13131.1 - 5.9 7.2 9.6 0.58 10.4 4.1 2.2 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DUF167 PF02594.16 KEG13133.1 - 7.2e-18 64.5 0.1 2.4e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 LRR_4 PF12799.7 KEG13135.1 - 2.4e-09 37.3 0.3 0.8 10.2 0.0 6.1 3 1 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEG13135.1 - 1.3e-06 28.0 5.1 0.54 10.4 0.0 7.1 8 0 0 8 8 8 3 Leucine Rich repeat Dus PF01207.17 KEG13136.1 - 2.6e-56 191.0 0.0 3.4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KEG13136.1 - 0.0038 16.6 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KEG13136.1 - 0.0059 16.1 0.0 0.019 14.4 0.0 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KEG13136.1 - 0.028 13.8 0.2 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.17 KEG13136.1 - 0.038 13.3 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase CH_2 PF06294.11 KEG13138.1 - 8.1e-31 106.0 0.0 1.3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KEG13138.1 - 2.9e-23 81.5 0.0 4.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Phage_lysis PF03245.13 KEG13138.1 - 0.0041 17.2 1.9 0.28 11.3 0.0 2.6 2 1 1 3 3 3 1 Bacteriophage Rz lysis protein TMF_DNA_bd PF12329.8 KEG13138.1 - 0.028 14.4 3.9 1.6 8.8 2.6 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 KEG13138.1 - 0.091 13.1 0.1 1.5 9.2 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CH PF00307.31 KEG13138.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain ATG16 PF08614.11 KEG13138.1 - 0.43 10.8 4.6 1.6 8.9 4.6 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MAGE_N PF12440.8 KEG13138.1 - 1.4 9.6 7.5 3.9 8.2 7.5 1.7 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal SBDS PF01172.18 KEG13139.1 - 4e-25 87.7 0.4 7.3e-25 86.9 0.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KEG13139.1 - 4.5e-24 84.7 0.3 1.4e-23 83.1 0.1 1.9 2 0 0 2 2 2 1 SBDS protein C-terminal domain Acyltransferase PF01553.21 KEG13142.1 - 3.5e-17 62.3 0.0 8.2e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase LRR_12 PF18837.1 KEG13142.1 - 0.16 11.7 0.1 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat Lipase_3 PF01764.25 KEG13143.1 - 9.2e-05 22.3 0.2 0.00032 20.6 0.2 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF21 PF01595.20 KEG13143.1 - 0.003 17.3 0.1 0.013 15.2 0.1 2.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain PGAP1 PF07819.13 KEG13143.1 - 0.0039 16.9 0.2 0.041 13.6 0.0 2.6 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEG13143.1 - 0.031 14.9 0.1 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 KEG13143.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MARVEL PF01284.23 KEG13143.1 - 0.59 10.2 6.9 0.15 12.1 0.6 3.1 2 1 0 2 2 2 0 Membrane-associating domain WWE PF02825.20 KEG13144.1 - 7.1e-05 23.3 0.1 0.00039 21.0 0.1 2.3 1 1 0 1 1 1 1 WWE domain FHA PF00498.26 KEG13144.1 - 0.00055 20.2 0.0 0.0034 17.7 0.0 2.4 3 0 0 3 3 3 1 FHA domain SVIP PF15811.5 KEG13144.1 - 3.7 8.1 10.7 7.1 7.2 3.6 2.7 2 0 0 2 2 2 0 Small VCP/p97-interacting protein UQ_con PF00179.26 KEG13145.1 - 8e-19 67.7 0.0 1.1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RRM_1 PF00076.22 KEG13146.1 - 7.5e-06 25.7 0.0 0.00059 19.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KEG13146.1 - 0.0041 17.2 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 KEG13146.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG13146.1 - 0.2 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif eIF-3c_N PF05470.12 KEG13147.1 - 1.2e-20 73.4 17.9 1.8e-17 62.9 1.4 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1708 PF08101.11 KEG13147.1 - 0.00078 18.7 0.6 0.0014 17.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PCI PF01399.27 KEG13147.1 - 0.015 15.8 0.0 0.071 13.6 0.0 2.3 1 0 0 1 1 1 0 PCI domain M11L PF11099.8 KEG13147.1 - 0.021 15.1 0.2 0.021 15.1 0.2 2.9 4 0 0 4 4 4 0 Apoptosis regulator M11L like Methyltransf_23 PF13489.6 KEG13149.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2194 PF09960.9 KEG13149.1 - 0.015 13.7 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) SKA2 PF16740.5 KEG13150.1 - 0.0052 16.6 23.8 0.29 10.9 5.0 4.6 2 2 1 3 3 3 2 Spindle and kinetochore-associated protein 2 Vps23_core PF09454.10 KEG13150.1 - 0.019 14.9 1.0 0.062 13.3 0.3 2.2 2 0 0 2 2 2 0 Vps23 core domain NUDE_C PF04880.13 KEG13150.1 - 0.035 14.6 0.3 0.035 14.6 0.3 3.7 1 1 2 4 4 4 0 NUDE protein, C-terminal conserved region FlaC_arch PF05377.11 KEG13150.1 - 4.2 7.8 12.5 12 6.3 0.1 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) FA_desaturase PF00487.24 KEG13151.1 - 2e-30 106.5 14.4 2.9e-30 105.9 14.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Thioredoxin PF00085.20 KEG13152.1 - 5.7e-61 202.9 0.9 3.1e-32 110.6 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KEG13152.1 - 1.1e-32 113.4 0.3 1.1e-22 80.9 0.0 3.8 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KEG13152.1 - 6.1e-13 49.2 1.0 1.6e-07 31.8 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KEG13152.1 - 4.5e-09 36.4 0.0 0.0016 18.5 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KEG13152.1 - 8e-08 32.2 0.2 0.0012 18.7 0.0 3.1 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KEG13152.1 - 1.1e-07 32.1 0.2 0.077 13.3 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like ERp29_N PF07912.13 KEG13152.1 - 1.6e-06 28.3 0.2 0.0051 17.0 0.0 3.7 4 0 0 4 4 4 1 ERp29, N-terminal domain TraF PF13728.6 KEG13152.1 - 2.3e-05 24.3 0.0 0.027 14.3 0.0 2.8 3 0 0 3 3 3 2 F plasmid transfer operon protein OST3_OST6 PF04756.13 KEG13152.1 - 3.5e-05 23.3 0.1 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 KEG13152.1 - 6.1e-05 22.8 0.2 0.053 13.2 0.0 3.4 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 KEG13152.1 - 0.0013 18.8 0.2 0.48 10.5 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KEG13152.1 - 0.0015 18.7 0.3 0.27 11.4 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin HyaE PF07449.11 KEG13152.1 - 0.011 15.7 0.0 0.59 10.1 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Calsequestrin PF01216.17 KEG13152.1 - 0.039 13.0 0.3 0.2 10.7 0.0 2.2 2 1 0 2 2 2 0 Calsequestrin Thioredoxin_9 PF14595.6 KEG13152.1 - 0.047 13.5 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DUF5483 PF17581.2 KEG13154.1 - 0.025 13.5 0.0 0.027 13.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5483) zf-H2C2_2 PF13465.6 KEG13155.1 - 0.027 14.9 0.5 0.061 13.8 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KEG13155.1 - 0.051 13.6 0.6 0.081 13.0 0.6 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger SSB PF00436.25 KEG13155.1 - 0.063 13.3 0.0 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Single-strand binding protein family Ribosomal_L1 PF00687.21 KEG13156.1 - 1.5e-15 57.5 0.0 2.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cpn60_TCP1 PF00118.24 KEG13157.1 - 1.9e-152 508.4 12.2 2.1e-152 508.2 12.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF374 PF04028.13 KEG13157.1 - 0.046 13.3 0.1 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) PrpR_N PF06506.11 KEG13157.1 - 0.05 13.2 0.9 0.55 9.8 0.1 2.4 2 0 0 2 2 2 0 Propionate catabolism activator LRR_4 PF12799.7 KEG13158.1 - 7.3e-05 23.1 0.8 0.011 16.2 0.2 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG13158.1 - 0.0032 17.2 0.3 0.052 13.3 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat Nucleoporin_N PF08801.11 KEG13159.1 - 4.5e-74 249.7 0.0 9.9e-74 248.6 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Bromodomain PF00439.25 KEG13161.1 - 3.1e-16 59.2 0.0 6.3e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain FNIP_M PF14637.6 KEG13161.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain EVE PF01878.18 KEG13163.1 - 8.6e-52 175.0 0.0 9.7e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 EVE domain RNA_lig_T4_1 PF09511.10 KEG13165.1 - 4.1e-20 72.6 0.0 9.1e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 RNA ligase AAA_18 PF13238.6 KEG13165.1 - 3.6e-12 47.0 0.0 8.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG13165.1 - 8.4e-12 45.4 0.1 4e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEG13165.1 - 0.0007 19.6 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEG13165.1 - 0.0012 19.2 0.1 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEG13165.1 - 0.0017 18.8 0.0 0.0047 17.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG13165.1 - 0.014 15.8 0.2 0.091 13.1 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KEG13165.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEG13165.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEG13165.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KEG13165.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 KEG13165.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2096 PF09869.9 KEG13165.1 - 0.084 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) RsgA_GTPase PF03193.16 KEG13165.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KEG13165.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 KEG13165.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEG13165.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MeaB PF03308.16 KEG13165.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KEG13165.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 KEG13165.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KEG13165.1 - 0.18 11.7 0.0 0.59 10.0 0.0 1.9 1 1 0 1 1 1 0 NTPase Ribosomal_S21e PF01249.18 KEG13167.1 - 1.2e-32 111.8 0.1 1.8e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21e DUF1147 PF06615.11 KEG13167.1 - 0.036 14.1 0.3 7.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Peptidase_C11 PF03415.14 KEG13171.1 - 1.7e-10 40.8 0.2 2.5e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 Clostripain family DUF2316 PF10078.9 KEG13171.1 - 0.7 10.2 4.5 20 5.5 0.5 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Atg14 PF10186.9 KEG13172.1 - 0.0035 16.5 6.6 0.0035 16.5 6.6 3.1 2 1 1 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 PhnJ PF06007.11 KEG13172.1 - 0.17 10.9 3.2 1.8 7.5 0.3 2.3 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnJ DUF4407 PF14362.6 KEG13172.1 - 2.1 7.7 31.0 0.81 9.0 3.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) LXG PF04740.12 KEG13172.1 - 5.9 6.6 16.0 0.41 10.3 3.0 3.5 2 1 2 4 4 4 0 LXG domain of WXG superfamily Spc7 PF08317.11 KEG13172.1 - 7.5 5.3 43.3 0.11 11.3 8.0 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein ArsA_ATPase PF02374.15 KEG13173.1 - 4.2e-93 311.9 0.0 5.6e-93 311.5 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KEG13173.1 - 3.6e-08 33.5 0.2 9.1e-05 22.4 0.2 2.7 2 1 0 2 2 2 2 AAA domain CbiA PF01656.23 KEG13173.1 - 1.2e-07 31.8 0.0 8.4e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KEG13173.1 - 0.0011 18.6 0.2 0.0059 16.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 KEG13173.1 - 0.0033 16.9 0.4 0.017 14.6 0.1 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KEG13173.1 - 0.01 15.3 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KEG13173.1 - 0.021 14.5 0.2 1.1 8.8 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KEG13173.1 - 0.14 11.3 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain MFS_1 PF07690.16 KEG13174.1 - 3.8e-16 59.0 33.9 1.4e-13 50.5 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG13174.1 - 8.3e-10 38.6 16.9 8.3e-10 38.6 16.9 2.9 2 1 0 2 2 2 1 Nodulin-like YajC PF02699.15 KEG13174.1 - 0.12 12.3 0.0 0.43 10.5 0.0 2.0 1 0 0 1 1 1 0 Preprotein translocase subunit FAM176 PF14851.6 KEG13175.1 - 0.046 13.4 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 FAM176 family DASH_Spc19 PF08287.11 KEG13175.1 - 0.058 13.3 0.2 0.096 12.6 0.2 1.3 1 0 0 1 1 1 0 Spc19 Tweety PF04906.13 KEG13175.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Tweety Protocadherin PF08374.11 KEG13175.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Ank_4 PF13637.6 KEG13176.1 - 1e-20 73.8 0.1 4.6e-07 30.3 0.0 5.0 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG13176.1 - 6.7e-18 65.1 0.0 5.5e-07 30.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG13176.1 - 5.6e-15 55.2 3.5 0.00012 22.3 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEG13176.1 - 8.4e-12 45.0 1.3 0.093 13.2 0.0 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KEG13176.1 - 7.3e-10 38.2 0.2 0.0086 16.5 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat TilS_C PF11734.8 KEG13176.1 - 0.11 11.9 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 TilS substrate C-terminal domain MFS_1 PF07690.16 KEG13177.1 - 8.5e-22 77.5 31.3 3.4e-16 59.1 20.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG13177.1 - 3.2e-06 26.8 20.7 3.2e-06 26.8 20.7 2.8 2 1 0 2 2 2 1 Nodulin-like DUF1129 PF06570.11 KEG13177.1 - 0.46 10.0 7.6 0.085 12.3 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Oleosin PF01277.17 KEG13177.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.9 5 1 0 5 5 5 0 Oleosin BTB_2 PF02214.22 KEG13178.1 - 2.6e-14 53.3 0.0 4.6e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain WD40 PF00400.32 KEG13178.1 - 3.4e-10 40.3 6.6 0.0015 19.3 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG13178.1 - 0.065 13.7 8.2 1.7 9.2 0.0 5.0 6 0 0 6 6 6 0 PQQ-like domain MFS_1 PF07690.16 KEG13179.1 - 1.2e-15 57.3 30.6 7.9e-15 54.6 18.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEG13179.1 - 5.9e-07 29.2 13.8 5.9e-07 29.2 13.8 2.8 2 2 1 3 3 3 1 Nodulin-like DUF1129 PF06570.11 KEG13179.1 - 0.39 10.2 7.0 0.37 10.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3671 PF12420.8 KEG13179.1 - 2.5 8.2 5.5 13 5.9 1.0 3.7 2 1 1 3 3 3 0 Protein of unknown function Nodulin-like PF06813.13 KEG13180.1 - 1.3e-10 41.2 14.9 1.3e-10 41.2 14.9 2.3 2 1 0 2 2 2 1 Nodulin-like DUF21 PF01595.20 KEG13180.1 - 0.86 9.3 12.4 1.2 8.8 0.5 3.2 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain SP_C-Propep PF08999.10 KEG13180.1 - 6.1 6.7 5.6 1.6 8.5 0.4 2.8 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide T3SS_needle_E PF08988.10 KEG13181.1 - 0.002 18.2 0.1 0.0054 16.8 0.1 1.7 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle Ribosomal_L24e PF01246.20 KEG13182.1 - 4.8e-32 110.0 3.2 1.1e-31 108.8 3.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e NosL PF05573.12 KEG13182.1 - 0.11 12.9 2.2 7.3 6.9 0.2 2.1 1 1 0 2 2 2 0 NosL zf-FCS PF06467.14 KEG13182.1 - 0.42 10.6 4.0 0.68 9.9 4.0 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif YqzE PF14038.6 KEG13182.1 - 8 6.5 7.2 17 5.5 0.3 2.4 2 0 0 2 2 2 0 YqzE-like protein LRR_6 PF13516.6 KEG13183.1 - 3.1e-24 82.9 21.7 0.38 10.9 0.0 14.8 16 0 0 16 16 16 8 Leucine Rich repeat LRR_4 PF12799.7 KEG13183.1 - 1.5e-13 50.7 21.7 0.0056 17.1 0.0 10.1 9 4 1 10 10 10 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG13183.1 - 4.8e-07 29.4 20.8 28 5.8 0.0 12.6 14 0 0 14 14 14 1 Leucine Rich Repeat LRR_8 PF13855.6 KEG13183.1 - 7.1e-06 25.7 33.3 1.2 8.9 1.4 11.8 9 4 2 11 11 11 5 Leucine rich repeat UPF0154 PF03672.13 KEG13183.1 - 0.092 12.8 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Metal_resist PF13801.6 KEG13184.1 - 0.029 14.5 2.6 0.029 14.5 2.6 1.9 2 0 0 2 2 2 0 Heavy-metal resistance START PF01852.19 KEG13185.1 - 3.4e-18 65.8 0.0 5.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 START domain Kinesin PF00225.23 KEG13186.1 - 2.3e-92 309.5 0.0 3.5e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG13186.1 - 5.2e-22 78.4 0.0 1.6e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding MIF4G PF02854.19 KEG13187.1 - 5.2e-05 23.0 0.0 0.11 12.2 0.0 3.3 3 0 0 3 3 3 2 MIF4G domain TFIIA PF03153.13 KEG13187.1 - 0.56 10.2 30.6 0.021 14.9 17.9 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 KEG13188.1 - 3.5e-07 29.9 0.3 0.0046 17.1 0.1 5.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KEG13188.1 - 0.0022 18.0 0.0 0.0084 16.2 0.0 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KEG13188.1 - 0.0069 15.0 0.1 0.041 12.4 0.0 2.3 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 KEG13188.1 - 0.024 15.2 0.3 0.024 15.2 0.3 4.4 4 0 0 4 4 4 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KEG13188.1 - 0.097 13.0 0.5 1.3 9.4 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion FAM199X PF15814.5 KEG13188.1 - 0.22 10.5 1.6 4.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein family FAM199X HEAT_2 PF13646.6 KEG13188.1 - 0.71 10.3 18.2 0.17 12.3 2.6 5.2 5 2 1 6 6 6 0 HEAT repeats DUF4407 PF14362.6 KEG13189.1 - 0.088 12.2 2.9 0.064 12.6 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 KEG13189.1 - 7.2 6.8 7.6 27 5.0 1.4 3.3 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Hydrolase_4 PF12146.8 KEG13192.1 - 4.8e-05 22.7 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG13192.1 - 0.00028 20.6 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2_jaz PF12171.8 KEG13193.1 - 3e-08 33.7 4.2 4.7e-08 33.1 4.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEG13193.1 - 8.2e-06 26.0 1.4 1.3e-05 25.4 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KEG13193.1 - 0.0013 19.0 0.1 0.0027 18.0 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 KEG13193.1 - 0.065 13.7 0.3 0.13 12.8 0.3 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 KEG13193.1 - 0.15 13.0 0.2 0.24 12.3 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger OPA3 PF07047.12 KEG13193.1 - 8.7 6.1 8.7 1.8 8.3 1.9 2.6 2 1 1 3 3 3 0 Optic atrophy 3 protein (OPA3) zf-DNL PF05180.12 KEG13194.1 - 8.9e-28 96.0 0.6 1.4e-27 95.4 0.6 1.3 1 0 0 1 1 1 1 DNL zinc finger DUF1364 PF07102.12 KEG13194.1 - 0.0012 18.7 1.0 0.0014 18.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1364) CGGC PF08821.11 KEG13194.1 - 0.011 15.9 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 CGGC domain DUF2325 PF10087.9 KEG13194.1 - 0.02 15.0 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Elf1 PF05129.13 KEG13194.1 - 0.022 14.8 0.3 0.038 14.0 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CSL PF05207.13 KEG13194.1 - 0.11 12.3 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger ParcG PF10274.9 KEG13195.1 - 2.4e-77 259.2 0.0 2.9e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 KEG13195.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PCI PF01399.27 KEG13196.1 - 1.9e-14 54.0 0.0 4.8e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 PCI domain DUF4003 PF13170.6 KEG13196.1 - 0.061 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) His_Phos_2 PF00328.22 KEG13197.1 - 2.3e-09 37.1 0.0 4.3e-08 32.9 0.0 2.3 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) IN_DBD_C PF00552.21 KEG13197.1 - 0.0015 17.8 0.1 0.0053 16.0 0.0 1.9 2 0 0 2 2 2 1 Integrase DNA binding domain Fib_alpha PF08702.10 KEG13198.1 - 0.00019 21.7 11.4 0.00078 19.6 2.1 2.4 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 KEG13198.1 - 0.0015 18.4 7.5 0.0034 17.3 7.5 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain EspB PF05802.11 KEG13198.1 - 0.029 14.4 5.9 0.063 13.3 5.9 1.5 1 0 0 1 1 1 0 Enterobacterial EspB protein Exonuc_VII_L PF02601.15 KEG13198.1 - 0.03 13.9 5.5 0.052 13.1 5.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4404 PF14357.6 KEG13198.1 - 0.042 14.5 10.6 0.71 10.5 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3450 PF11932.8 KEG13198.1 - 0.046 13.0 6.4 0.068 12.5 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TBCC_N PF16752.5 KEG13198.1 - 0.54 10.7 14.9 0.081 13.4 2.5 3.2 2 2 2 4 4 3 0 Tubulin-specific chaperone C N-terminal domain DUF883 PF05957.13 KEG13198.1 - 0.67 10.6 4.6 0.74 10.4 0.7 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 KEG13198.1 - 1.1 9.3 8.9 8.8 6.4 1.6 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad4 PF08650.10 KEG13198.1 - 1.4 8.9 4.2 2.4 8.2 0.4 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad4 Phasin PF05597.11 KEG13198.1 - 2.5 8.1 8.6 1.3 9.1 1.3 2.9 1 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF948 PF06103.11 KEG13198.1 - 4.8 7.5 6.9 13 6.2 1.5 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Pex2_Pex12 PF04757.14 KEG13199.1 - 2.7e-33 115.5 6.9 3.1e-33 115.2 6.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 KEG13199.1 - 0.0003 20.6 9.6 0.00053 19.8 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEG13199.1 - 0.00051 20.1 2.0 0.00051 20.1 2.0 1.8 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KEG13199.1 - 0.0011 18.7 8.8 0.0017 18.2 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_5 PF12688.7 KEG13199.1 - 0.049 13.9 1.9 0.37 11.0 0.5 2.4 1 1 0 2 2 2 0 Tetratrico peptide repeat TF_Zn_Ribbon PF08271.12 KEG13199.1 - 0.062 12.8 2.0 0.15 11.6 2.0 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_5 PF14634.6 KEG13199.1 - 0.064 13.2 8.7 0.21 11.6 8.8 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEG13199.1 - 0.081 13.0 7.2 0.074 13.1 5.8 1.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 KEG13199.1 - 0.14 12.5 8.3 0.24 11.8 8.3 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KEG13199.1 - 0.47 10.4 7.7 0.75 9.7 7.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEG13199.1 - 2.2 8.2 8.3 4.4 7.2 8.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KEG13200.1 - 0.0018 18.2 10.5 0.0018 18.2 10.5 2.5 2 1 1 3 3 3 1 PHD-finger Prok-RING_1 PF14446.6 KEG13200.1 - 1.3 9.0 10.2 0.13 12.2 2.7 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DHHC PF01529.20 KEG13205.1 - 1.5e-34 119.0 2.7 1.5e-34 119.0 2.7 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pex2_Pex12 PF04757.14 KEG13206.1 - 4.3e-16 59.2 1.7 2.6e-14 53.4 1.7 2.1 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KEG13206.1 - 4e-10 39.9 7.8 6.3e-10 39.2 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEG13206.1 - 6e-09 35.6 5.1 9.4e-09 35.0 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG13206.1 - 9.3e-09 35.0 5.8 1.4e-08 34.4 5.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEG13206.1 - 1.1e-07 31.6 6.8 1.7e-07 31.0 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG13206.1 - 2.6e-07 30.5 5.8 4.4e-07 29.8 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KEG13206.1 - 3e-06 27.3 6.7 4.9e-06 26.6 6.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KEG13206.1 - 5.3e-06 26.2 7.5 8.7e-06 25.5 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG13206.1 - 2.1e-05 24.4 2.4 2.1e-05 24.4 2.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KEG13206.1 - 4.4e-05 23.7 5.4 7.1e-05 23.0 5.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEG13206.1 - 0.00015 21.7 2.2 0.00025 21.0 2.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MscS_TM PF12794.7 KEG13206.1 - 0.064 12.1 0.9 0.079 11.8 0.0 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 TerY_C PF15616.6 KEG13206.1 - 0.12 12.5 0.7 0.19 11.8 0.7 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain FANCL_C PF11793.8 KEG13206.1 - 0.19 11.9 6.0 1.2 9.4 6.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KEG13206.1 - 0.3 10.9 7.0 0.61 9.9 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KEG13206.1 - 0.43 10.5 3.3 1 9.3 3.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 KEG13206.1 - 2 8.7 7.2 6.1 7.1 7.2 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain LRR_8 PF13855.6 KEG13207.1 - 2.4e-06 27.2 0.9 5.7e-06 26.0 0.2 2.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KEG13207.1 - 4.1e-06 27.0 1.9 4.1e-05 23.9 0.2 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 KEG13207.1 - 4.1e-05 24.0 0.0 0.00015 22.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG13207.1 - 5.3e-05 22.8 0.0 0.015 15.2 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KEG13207.1 - 6.9e-05 22.1 0.0 0.0015 17.9 0.0 3.0 3 0 0 3 3 3 1 EF hand OGG_N PF07934.12 KEG13207.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain AEP1 PF17049.5 KEG13207.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase expression protein 1 EF-hand_8 PF13833.6 KEG13207.1 - 0.1 12.4 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Lebercilin PF15619.6 KEG13207.1 - 0.2 11.3 3.6 0.11 12.2 1.2 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease LRR_1 PF00560.33 KEG13207.1 - 0.31 11.7 0.9 37 5.4 0.0 3.7 4 0 0 4 4 3 0 Leucine Rich Repeat ERM PF00769.19 KEG13207.1 - 0.33 10.7 3.2 0.25 11.1 1.2 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 KEG13207.1 - 0.39 10.8 5.5 2.2 8.4 2.6 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation GIT_CC PF16559.5 KEG13207.1 - 0.73 9.8 3.6 0.6 10.0 1.0 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SPC12 PF06645.13 KEG13209.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) VPS9 PF02204.18 KEG13210.1 - 7.3e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 KEG13210.1 - 1.9e-05 24.2 6.3 0.0015 18.3 0.0 5.3 6 0 0 6 6 6 1 MORN repeat Pkinase PF00069.25 KEG13211.1 - 4.8e-61 206.4 0.0 6e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13211.1 - 1.1e-36 126.4 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG13211.1 - 2.7e-05 23.6 0.0 0.00011 21.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEG13211.1 - 0.072 13.0 0.0 0.6 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Type_III_YscX PF09474.10 KEG13213.1 - 0.17 12.2 1.2 1.4 9.2 0.0 2.9 3 1 0 3 3 3 0 Type III secretion system YscX (type_III_YscX) DUF1978 PF09321.10 KEG13215.1 - 0.062 12.6 0.9 0.11 11.8 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) PRMT5 PF05185.16 KEG13216.1 - 1.6e-41 142.1 0.0 2.3e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KEG13216.1 - 2.3e-23 83.0 0.0 3.7e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Cyt-b5 PF00173.28 KEG13217.1 - 4.3e-06 26.8 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain E1_dh PF00676.20 KEG13218.1 - 7.6e-84 281.2 1.6 1.9e-49 168.3 0.0 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEG13218.1 - 0.023 13.9 2.0 11 5.1 0.1 3.2 2 1 1 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase DUF393 PF04134.12 KEG13219.1 - 9.5e-05 23.7 5.3 0.15 13.4 0.2 2.4 1 1 1 2 2 2 2 Protein of unknown function, DUF393 DUF971 PF06155.12 KEG13220.1 - 8.1e-16 58.4 0.0 1.4e-15 57.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF971) DUF2442 PF10387.9 KEG13220.1 - 0.008 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2442) DHHC PF01529.20 KEG13221.1 - 4.2e-30 104.6 10.1 4.2e-30 104.6 10.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase UL41A PF17591.2 KEG13221.1 - 7.4 6.8 7.9 48 4.1 0.1 2.6 2 0 0 2 2 2 0 Herpesvirus UL41A AATF-Che1 PF13339.6 KEG13223.1 - 0.042 14.5 1.0 0.082 13.6 1.0 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF1706 PF08020.11 KEG13223.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) PB1 PF00564.24 KEG13225.1 - 1e-06 28.5 0.1 3.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 PB1 domain TraB PF01963.17 KEG13225.1 - 0.11 12.4 0.6 0.2 11.5 0.6 1.4 1 0 0 1 1 1 0 TraB family FSA_C PF10479.9 KEG13225.1 - 9.7 4.2 14.3 15 3.5 14.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus V-ATPase_H_N PF03224.14 KEG13226.1 - 1.2e-67 228.4 0.0 1.8e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KEG13226.1 - 6.6e-40 135.9 0.1 2.5e-38 130.8 0.0 2.8 3 0 0 3 3 3 1 V-ATPase subunit H zf-HC2 PF13490.6 KEG13226.1 - 0.035 14.4 0.1 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 Putative zinc-finger Peptidase_M8 PF01457.16 KEG13227.1 - 2.8e-123 412.4 6.6 6.9e-63 213.1 0.1 2.0 2 0 0 2 2 2 2 Leishmanolysin HAP2-GCS1 PF10699.9 KEG13227.1 - 0.047 13.7 1.2 0.22 11.5 0.3 2.2 2 0 0 2 2 2 0 Male gamete fusion factor Glycos_transf_1 PF00534.20 KEG13231.1 - 3.6e-34 117.8 0.0 5.7e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEG13231.1 - 1.2e-18 67.9 0.1 8.7e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEG13231.1 - 1.5e-06 28.3 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEG13231.1 - 6.4e-06 26.5 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 SVIP PF15811.5 KEG13231.1 - 0.11 13.0 0.6 0.22 12.0 0.6 1.5 1 0 0 1 1 1 0 Small VCP/p97-interacting protein TPR_1 PF00515.28 KEG13232.1 - 3.3e-25 86.8 23.4 3.4e-07 29.8 0.1 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13232.1 - 1e-20 72.1 26.8 0.00097 19.1 0.1 9.1 9 1 0 9 9 9 5 Tetratricopeptide repeat DnaJ PF00226.31 KEG13232.1 - 1.9e-20 72.7 0.1 5e-20 71.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.6 KEG13232.1 - 1e-13 50.3 12.4 0.039 14.2 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEG13232.1 - 2.6e-13 50.3 9.7 0.011 16.3 0.1 6.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13232.1 - 3.9e-10 39.3 12.4 0.0064 16.2 0.4 6.3 4 1 2 6 6 6 3 TPR repeat TPR_17 PF13431.6 KEG13232.1 - 3.6e-08 33.3 7.9 0.066 13.6 0.0 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KEG13232.1 - 3.9e-06 26.9 0.7 0.00023 21.2 0.0 3.2 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.6 KEG13232.1 - 5.9e-06 26.5 26.0 0.0028 17.9 0.8 7.3 5 1 3 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13232.1 - 0.0001 22.4 7.1 0.02 15.0 0.2 5.1 4 2 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13232.1 - 0.00015 21.9 11.1 0.07 13.4 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KEG13232.1 - 0.00025 20.8 9.9 0.7 10.1 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13232.1 - 0.0003 21.3 24.3 2.6 9.1 0.1 8.4 5 3 4 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEG13232.1 - 0.0047 17.5 14.7 1.3 9.8 0.2 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KEG13232.1 - 0.0059 16.6 5.2 0.095 12.7 0.0 3.7 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_16 PF13432.6 KEG13232.1 - 0.04 14.6 28.5 0.078 13.6 0.1 6.9 6 1 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 KEG13232.1 - 0.56 10.3 10.4 17 5.6 0.3 5.8 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain Sec7 PF01369.20 KEG13234.1 - 3.4e-39 134.4 0.0 5.9e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KEG13234.1 - 3.7e-09 36.7 0.2 7.5e-08 32.4 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 KEG13234.1 - 0.06 13.4 0.7 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Peptidase_M64 PF09471.10 KEG13235.1 - 1.9e-11 44.0 0.0 6.1e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 IgA Peptidase M64 Tetraspanin PF00335.20 KEG13235.1 - 5.4e-07 29.6 9.0 5.4e-07 29.6 9.0 1.9 2 0 0 2 2 2 1 Tetraspanin family LapA_dom PF06305.11 KEG13235.1 - 0.5 10.2 4.2 0.76 9.6 1.5 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain GTP_EFTU PF00009.27 KEG13236.1 - 1.7e-09 37.5 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEG13236.1 - 0.00046 20.1 0.2 0.07 13.0 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KEG13236.1 - 0.002 18.3 0.1 0.0034 17.5 0.1 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain ABC_tran PF00005.27 KEG13236.1 - 0.0045 17.5 0.0 0.0099 16.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KEG13236.1 - 0.015 14.8 1.2 14 5.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KEG13236.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEG13236.1 - 0.028 14.8 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KEG13236.1 - 0.028 14.1 0.1 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEG13236.1 - 0.056 13.8 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEG13236.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KEG13236.1 - 0.13 12.4 0.6 0.31 11.2 0.1 1.9 2 0 0 2 2 1 0 AAA domain V-SNARE PF05008.15 KEG13237.1 - 0.00036 20.9 1.3 0.00036 20.9 1.3 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus NUC205 PF08168.11 KEG13237.1 - 0.087 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 NUC205 domain CAP_N PF01213.19 KEG13237.1 - 0.4 10.1 4.9 0.6 9.5 3.7 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Seryl_tRNA_N PF02403.22 KEG13237.1 - 1.1 9.5 8.3 1.2 9.4 5.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KEG13237.1 - 4.8 6.0 14.3 19 4.0 12.7 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KEG13237.1 - 5.3 6.3 7.7 8.7 5.6 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L35Ae PF01247.18 KEG13238.1 - 1.2e-33 115.2 1.2 1.9e-33 114.5 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KEG13238.1 - 3.3e-05 24.0 0.9 0.17 12.1 0.1 2.4 2 1 0 2 2 2 2 RimM N-terminal domain TcA_RBD PF18518.1 KEG13238.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 TcA receptor binding domain TMEM192 PF14802.6 KEG13239.1 - 0.0099 15.0 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 TMEM192 family DUF202 PF02656.15 KEG13239.1 - 0.087 13.3 0.9 0.19 12.2 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2873 PF11395.8 KEG13240.1 - 8.6 6.3 8.6 0.78 9.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) ERM PF00769.19 KEG13242.1 - 0.0062 16.4 9.5 0.0062 16.4 9.5 5.6 2 1 3 5 5 5 4 Ezrin/radixin/moesin family Img2 PF05046.14 KEG13242.1 - 0.28 11.5 5.0 14 6.1 0.3 3.8 3 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) LRR_6 PF13516.6 KEG13243.1 - 0.00018 21.3 10.9 0.092 12.8 0.0 5.1 5 1 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 KEG13243.1 - 0.29 10.9 7.1 3.9 7.3 0.9 3.1 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 KEG13243.1 - 2.2 9.2 9.4 18 6.4 0.3 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KEG13243.1 - 2.8 8.5 8.3 21 5.7 0.4 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ANAPC4_WD40 PF12894.7 KEG13244.1 - 5.1e-11 42.7 0.5 0.041 14.2 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KEG13244.1 - 0.0024 17.7 1.0 2.2 8.2 0.1 4.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.32 KEG13244.1 - 0.06 14.2 5.4 4.2 8.4 0.0 4.5 4 1 0 4 4 4 0 WD domain, G-beta repeat Rad60-SLD PF11976.8 KEG13245.1 - 0.0016 18.2 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEG13245.1 - 0.0062 16.3 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Ub-RnfH PF03658.14 KEG13245.1 - 0.019 15.3 0.0 0.086 13.2 0.0 2.0 2 0 0 2 2 2 0 RnfH family Ubiquitin DUF2856 PF11043.8 KEG13246.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Nmad5 PF18757.1 KEG13246.1 - 0.11 12.7 0.6 0.21 11.8 0.1 1.6 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 Cep57_CLD_2 PF14197.6 KEG13246.1 - 2.3 8.4 10.7 0.33 11.1 1.2 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 BRO1 PF03097.18 KEG13247.1 - 7.4e-23 81.0 0.0 9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain TFIID_NTD2 PF04494.15 KEG13247.1 - 0.013 15.7 0.1 0.023 14.9 0.1 1.4 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain CoA_binding PF02629.19 KEG13248.1 - 2.4e-27 95.5 1.8 2.4e-27 95.5 1.8 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KEG13248.1 - 9.8e-22 77.4 2.4 1.1e-21 77.2 0.3 1.9 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 KEG13248.1 - 1.3e-06 28.3 0.0 2.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KEG13248.1 - 7.1e-05 23.3 0.0 0.00023 21.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain eIF3_subunit PF08597.10 KEG13249.1 - 2.7e-11 43.9 24.9 3.5e-11 43.5 24.9 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRTP PF01366.18 KEG13249.1 - 4.4 5.2 6.8 5 5.1 6.4 1.2 1 1 0 1 1 1 0 Herpesvirus processing and transport protein KBP_C PF12309.8 KEG13250.1 - 2e-61 208.5 0.7 5.6e-53 180.7 0.2 2.4 2 0 0 2 2 2 2 KIF-1 binding protein C terminal LPD39 PF18858.1 KEG13250.1 - 0.65 10.1 3.9 37 4.3 0.0 3.6 4 0 0 4 4 4 0 Large polyvalent protein associated domain 39 Snapin_Pallidin PF14712.6 KEG13251.1 - 0.0011 19.3 0.4 0.0011 19.3 0.4 2.7 3 1 1 4 4 4 1 Snapin/Pallidin Allexi_40kDa PF05549.11 KEG13251.1 - 0.006 16.1 0.4 1.3 8.4 0.1 2.1 2 0 0 2 2 2 2 Allexivirus 40kDa protein V-SNARE_C PF12352.8 KEG13251.1 - 0.022 15.0 1.2 0.036 14.4 0.3 1.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Occludin_ELL PF07303.13 KEG13251.1 - 0.24 12.2 4.1 2.7 8.8 0.4 2.4 2 0 0 2 2 2 0 Occludin homology domain CCDC-167 PF15188.6 KEG13251.1 - 0.77 10.1 3.9 0.63 10.4 0.1 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.12 KEG13251.1 - 0.88 9.6 4.9 1.8 8.6 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II TPR_2 PF07719.17 KEG13252.1 - 3.1e-21 73.7 17.4 3.4e-06 26.8 0.1 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13252.1 - 2e-20 71.7 13.6 1.7e-05 24.5 0.0 6.6 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13252.1 - 3.9e-14 51.6 6.7 0.0058 16.7 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13252.1 - 9e-13 48.3 18.0 0.0039 17.4 1.0 5.0 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13252.1 - 2.7e-10 40.2 16.9 0.29 12.1 0.2 6.2 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13252.1 - 1.6e-08 34.1 6.3 0.051 13.3 0.1 4.7 4 1 1 5 5 5 3 TPR repeat TPR_19 PF14559.6 KEG13252.1 - 5.1e-08 33.3 9.9 0.00018 22.0 1.3 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-C2H2_10 PF16588.5 KEG13252.1 - 1.6e-07 30.9 2.5 4.8e-07 29.4 2.5 1.8 1 0 0 1 1 1 1 C2H2 zinc-finger TPR_17 PF13431.6 KEG13252.1 - 1.2e-05 25.3 4.9 1.9 9.1 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13252.1 - 0.00015 21.9 14.6 0.001 19.3 2.9 3.0 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KEG13252.1 - 0.00018 22.1 15.5 0.091 13.4 1.7 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13252.1 - 0.00027 21.0 14.3 0.039 14.1 3.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEG13252.1 - 0.0042 16.9 13.0 1.4 8.9 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Kinesin_assoc PF16183.5 KEG13252.1 - 0.01 16.0 0.3 0.024 14.8 0.3 1.6 1 0 0 1 1 1 0 Kinesin-associated TPR_7 PF13176.6 KEG13252.1 - 0.015 15.3 16.9 0.21 11.7 0.4 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat zf-CCHC PF00098.23 KEG13252.1 - 0.07 13.2 2.1 0.13 12.4 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle TPR_20 PF14561.6 KEG13252.1 - 0.21 12.0 9.3 0.75 10.2 1.6 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG13252.1 - 0.29 11.9 9.1 20 6.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Com_YlbF PF06133.11 KEG13252.1 - 0.7 10.5 7.6 2 9.1 4.6 2.7 2 2 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA mRNA_triPase PF02940.15 KEG13253.1 - 1.9e-05 24.5 0.0 6.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain GTP_EFTU PF00009.27 KEG13255.1 - 1e-49 168.7 0.0 1.6e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEG13255.1 - 1.5e-18 66.6 0.0 3.1e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KEG13255.1 - 1.5e-06 28.0 0.0 5.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KEG13255.1 - 0.00012 22.4 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEG13255.1 - 0.0028 17.7 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 KEG13255.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rieske PF00355.26 KEG13256.1 - 1.1e-09 38.1 0.1 2.6e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KEG13256.1 - 1.4e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_6 PF08030.12 KEG13256.1 - 0.0078 16.4 0.0 0.7 10.0 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KEG13256.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SpoIIE PF07228.12 KEG13257.1 - 1.2e-12 48.2 0.1 8.1e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KEG13257.1 - 3.9e-05 23.4 0.0 0.00022 20.9 0.0 2.1 3 0 0 3 3 3 1 Protein phosphatase 2C PP2C_2 PF13672.6 KEG13257.1 - 0.0004 20.1 0.1 0.0011 18.6 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SNF2_N PF00176.23 KEG13258.1 - 5e-40 137.3 0.0 8.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG13258.1 - 5.4e-17 62.1 0.0 1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG13258.1 - 2.4e-08 34.2 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 KEG13258.1 - 2.3e-05 24.2 15.8 0.00029 20.7 2.1 3.2 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 KEG13258.1 - 0.0065 16.3 1.2 0.0065 16.3 1.2 3.0 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SWI2_SNF2 PF18766.1 KEG13258.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase C1_2 PF03107.16 KEG13258.1 - 0.031 14.6 1.0 0.031 14.6 1.0 2.8 3 0 0 3 3 3 0 C1 domain zf-PHD-like PF15446.6 KEG13258.1 - 0.15 11.7 7.3 0.63 9.6 1.1 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 KEG13258.1 - 0.4 10.8 8.0 0.3 11.2 5.5 2.2 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 KEG13258.1 - 1 9.0 7.5 0.58 9.8 0.6 2.9 2 0 0 2 2 2 0 PHD-finger PseudoU_synth_2 PF00849.22 KEG13259.1 - 8.7e-24 84.4 0.5 3e-23 82.7 0.5 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase SUIM_assoc PF16619.5 KEG13259.1 - 0.022 14.8 0.5 0.049 13.7 0.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NIF PF03031.18 KEG13261.1 - 1.5e-49 167.8 0.1 2.1e-49 167.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2777 PF10949.8 KEG13261.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) AAA_16 PF13191.6 KEG13262.1 - 5.2e-06 26.9 0.1 1.3e-05 25.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KEG13262.1 - 1.5e-05 24.8 0.7 0.00015 21.6 0.0 2.3 2 1 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 KEG13262.1 - 0.00036 20.5 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain Ploopntkinase2 PF18747.1 KEG13262.1 - 0.0089 15.3 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase2 AAA_18 PF13238.6 KEG13262.1 - 0.013 16.1 0.0 0.05 14.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEG13262.1 - 0.022 14.5 4.6 0.029 14.1 0.1 2.5 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 KEG13262.1 - 0.024 14.5 0.5 6.8 6.5 0.2 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KEG13262.1 - 0.03 13.6 0.3 0.48 9.7 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin SRP54 PF00448.22 KEG13262.1 - 0.053 13.1 3.6 0.078 12.6 0.4 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Sbi-IV PF11621.8 KEG13262.1 - 0.054 13.9 0.2 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI AAA_22 PF13401.6 KEG13262.1 - 0.057 13.7 0.1 0.1 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Poly_export PF02563.16 KEG13262.1 - 0.13 12.5 0.3 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein Spt20 PF12090.8 KEG13264.1 - 0.056 13.1 14.5 0.034 13.8 7.4 2.5 2 0 0 2 2 2 0 Spt20 family PTPlike_phytase PF14566.6 KEG13264.1 - 0.72 10.0 2.9 1.9 8.6 2.9 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate BSP_II PF05432.11 KEG13264.1 - 1.5 8.5 10.2 5.4 6.6 10.2 1.9 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PMSI1 PF15322.6 KEG13264.1 - 2.1 7.7 12.0 0.91 8.9 8.1 2.1 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative SUIM_assoc PF16619.5 KEG13264.1 - 2.4 8.3 21.3 3.9 7.6 0.0 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF966 PF06136.13 KEG13264.1 - 3.8 7.1 12.9 3 7.5 9.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Transket_pyr PF02779.24 KEG13265.1 - 7.2e-48 162.6 0.0 9.3e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEG13265.1 - 3.2e-39 133.6 0.0 7.3e-39 132.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF460 PF04312.13 KEG13265.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) PFOR_II PF17147.4 KEG13265.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II LSM PF01423.22 KEG13266.1 - 2.1e-14 53.0 0.2 2.8e-14 52.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEG13266.1 - 0.002 18.2 0.2 0.014 15.6 0.2 1.9 1 1 0 1 1 1 1 Ataxin 2 SM domain LRR_9 PF14580.6 KEG13267.1 - 2.6e-14 53.1 0.9 2e-12 46.9 0.0 2.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KEG13267.1 - 3.9e-09 36.1 8.9 1e-06 28.4 3.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KEG13267.1 - 5.1e-06 26.7 5.6 0.00025 21.4 0.7 3.6 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) DUF4570 PF15134.6 KEG13267.1 - 0.0054 16.7 6.5 0.0054 16.7 6.5 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4570) SUIM_assoc PF16619.5 KEG13267.1 - 0.79 9.8 28.8 0.1 12.7 9.2 4.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 LRR_6 PF13516.6 KEG13267.1 - 0.85 9.8 0.0 0.85 9.8 0.0 2.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KEG13267.1 - 0.91 10.3 6.1 6.6 7.7 0.1 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat Sde2_N_Ubi PF13019.6 KEG13267.1 - 2.5 7.9 9.4 0.14 12.0 1.9 2.7 3 0 0 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain MAT1 PF06391.13 KEG13267.1 - 9.5 6.0 17.7 6.3 6.6 5.5 3.2 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 HSCB_C PF07743.13 KEG13269.1 - 2.6e-07 31.0 1.7 6.3e-07 29.8 0.1 2.4 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KEG13269.1 - 0.00027 21.0 0.1 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain HORMA PF02301.18 KEG13270.1 - 1e-21 77.5 0.1 2.8e-21 76.1 0.1 1.6 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KEG13270.1 - 0.0056 16.5 0.2 0.014 15.2 0.2 1.6 1 1 0 1 1 1 1 Bacterial HORMA domain 2 SBP_bac_3 PF00497.20 KEG13270.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 EFP_N PF08207.12 KEG13272.1 - 7.1e-05 22.8 0.5 0.00011 22.2 0.5 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain GlcV_C_terminal PF17847.1 KEG13272.1 - 0.12 12.9 0.0 9.9 6.7 0.0 2.5 1 1 1 2 2 2 0 Glucose ABC transporter C-terminal domain COX6B PF02297.17 KEG13273.1 - 0.012 15.8 1.0 0.021 15.0 1.0 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KEG13273.1 - 0.033 14.3 2.2 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 CHCH domain DEC-1_N PF04625.13 KEG13273.1 - 1 8.3 3.8 0.91 8.5 3.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DAGAT PF03982.13 KEG13274.1 - 1.8e-81 273.3 0.0 2.5e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RSV_NS2 PF03113.14 KEG13274.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 JAB PF01398.21 KEG13276.1 - 8.4e-07 29.0 0.0 2.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KEG13276.1 - 5e-05 23.4 3.1 0.00088 19.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0172) WD-3 PF09765.9 KEG13276.1 - 0.014 14.7 1.3 0.023 14.0 1.3 1.3 1 0 0 1 1 1 0 WD-repeat region WD40 PF00400.32 KEG13277.1 - 3.3e-10 40.4 13.8 0.0018 19.0 0.1 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13277.1 - 1.9e-06 28.1 0.0 4e-05 23.8 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BRCT PF00533.26 KEG13278.1 - 9.3e-12 45.2 0.0 0.00075 19.8 0.0 4.4 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 KEG13278.1 - 1.5e-08 34.6 0.0 0.00065 19.7 0.1 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEG13278.1 - 2.8e-08 34.1 0.0 0.0089 16.4 0.0 4.3 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KEG13278.1 - 0.012 15.5 0.1 0.14 12.1 0.0 2.8 3 0 0 3 3 3 0 twin BRCT domain PufQ PF05398.11 KEG13278.1 - 0.11 12.6 0.1 1.7 8.8 0.1 2.7 2 0 0 2 2 2 0 PufQ cytochrome subunit ANAPC1 PF12859.7 KEG13278.1 - 2.9 8.5 5.4 0.73 10.4 0.4 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 Ependymin PF00811.18 KEG13280.1 - 0.014 15.7 0.1 0.041 14.1 0.2 1.7 2 0 0 2 2 2 0 Ependymin NIF PF03031.18 KEG13281.1 - 7.5e-20 71.3 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Spt20 PF12090.8 KEG13281.1 - 0.58 9.7 25.8 4.6 6.8 23.0 2.2 2 0 0 2 2 2 0 Spt20 family Ctr PF04145.15 KEG13281.1 - 2.2 8.9 3.9 19 5.9 1.1 2.4 2 0 0 2 2 2 0 Ctr copper transporter family EPL1 PF10513.9 KEG13281.1 - 2.9 8.3 11.5 5.4 7.4 5.0 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM60A PF15396.6 KEG13281.1 - 3.8 7.5 12.8 2 8.4 0.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Sporozoite_P67 PF05642.11 KEG13282.1 - 0.033 12.3 0.1 0.043 11.9 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3439 PF11921.8 KEG13282.1 - 4.4 7.3 10.0 10 6.1 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rieske PF00355.26 KEG13284.1 - 2.2e-13 50.0 0.0 4.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PIN_4 PF13638.6 KEG13285.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 PIN domain DnaJ PF00226.31 KEG13286.1 - 9.7e-19 67.3 0.4 1.8e-18 66.4 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain NTP_transf_3 PF12804.7 KEG13287.1 - 1.4 9.3 5.8 0.51 10.7 1.6 2.6 2 0 0 2 2 2 0 MobA-like NTP transferase domain Methyltransf_23 PF13489.6 KEG13288.1 - 3.7e-17 62.7 0.0 5.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG13288.1 - 6.9e-12 45.9 0.0 1.4e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG13288.1 - 5.1e-10 39.9 0.0 1e-09 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEG13288.1 - 7.7e-09 35.2 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEG13288.1 - 9e-07 29.6 0.0 2.5e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG13288.1 - 4.9e-05 23.2 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEG13288.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Fmp27_WPPW PF10359.9 KEG13288.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Peptidase_C14 PF00656.22 KEG13289.1 - 2e-56 191.7 0.0 2.6e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KEG13289.1 - 0.063 13.2 0.2 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain TMF_TATA_bd PF12325.8 KEG13290.1 - 0.0014 18.9 3.0 0.023 14.9 3.3 2.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF3085 PF11284.8 KEG13290.1 - 0.024 14.9 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) Spc7 PF08317.11 KEG13290.1 - 0.071 12.0 1.5 0.16 10.8 1.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_C98 PF15499.6 KEG13290.1 - 0.11 11.9 0.6 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Fez1 PF06818.15 KEG13290.1 - 0.33 11.4 2.3 0.37 11.2 0.7 1.9 2 0 0 2 2 2 0 Fez1 Nucleopor_Nup85 PF07575.13 KEG13291.1 - 0.011 14.3 0.0 0.065 11.8 0.0 2.0 2 0 0 2 2 2 0 Nup85 Nucleoporin DnaJ PF00226.31 KEG13293.1 - 0.051 13.7 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 DnaJ domain PhoD PF09423.10 KEG13294.1 - 1.7e-13 50.3 0.0 3.1e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase IMUP PF15761.5 KEG13296.1 - 0.066 13.9 7.7 0.14 12.8 7.7 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein AF-4 PF05110.13 KEG13296.1 - 0.12 10.4 10.5 0.16 10.0 10.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2312 PF10073.9 KEG13297.1 - 0.029 14.0 0.6 0.13 11.9 0.6 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) UvrD_C PF13361.6 KEG13297.1 - 0.032 13.6 0.4 3.5 6.9 1.3 2.2 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain LidA_Long_CC PF18641.1 KEG13297.1 - 0.53 10.3 8.0 0.4 10.7 0.9 2.9 2 0 0 2 2 2 0 LidA long coiled-coil domain GIT_CC PF16559.5 KEG13297.1 - 1.5 8.8 8.3 1.8 8.5 0.5 3.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2959 PF11172.8 KEG13297.1 - 1.8 8.7 16.1 0.086 13.0 5.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) DUF948 PF06103.11 KEG13297.1 - 3.4 8.0 6.5 21 5.5 0.3 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Robl_LC7 PF03259.17 KEG13298.1 - 1.4e-20 72.8 0.0 1.6e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KEG13298.1 - 0.023 14.6 0.0 0.032 14.2 0.0 1.4 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 Mito_carr PF00153.27 KEG13299.1 - 6.5e-26 90.1 3.6 3.1e-12 46.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein UDPGP PF01704.18 KEG13300.1 - 2.2e-121 405.4 0.0 2.7e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TcdB_N PF12918.7 KEG13301.1 - 0.0045 17.2 0.1 0.015 15.6 0.1 1.9 1 0 0 1 1 1 1 TcdB toxin N-terminal helical domain FUSC PF04632.12 KEG13301.1 - 1.8 7.0 4.1 2 6.9 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IQ PF00612.27 KEG13302.1 - 0.00078 19.0 6.5 0.54 10.2 5.3 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Mannosyl_trans2 PF04188.13 KEG13303.1 - 6.5e-33 114.7 19.7 2.6e-24 86.4 15.3 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V) DUF563 PF04577.14 KEG13304.1 - 4.9e-22 79.1 0.0 8.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Nrap_D5 PF17406.2 KEG13306.1 - 5.3e-27 94.6 0.1 1.3e-26 93.3 0.1 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KEG13306.1 - 1.4e-15 57.2 0.2 2.4e-15 56.5 0.2 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KEG13306.1 - 1.4e-14 54.5 0.0 3.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 DUF5582 PF17819.1 KEG13309.1 - 0.003 18.0 0.7 0.0086 16.5 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5582) EF-hand_7 PF13499.6 KEG13309.1 - 0.0036 17.7 0.0 0.014 15.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair DUF4400 PF14348.6 KEG13309.1 - 0.0048 16.4 0.1 0.0063 16.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) DUF1400 PF07176.11 KEG13309.1 - 0.048 14.0 0.6 0.083 13.2 0.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF4860 PF16152.5 KEG13309.1 - 0.086 12.7 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4860) Chorein_N PF12624.7 KEG13310.1 - 5.1e-23 81.4 1.6 1.7e-10 41.0 0.6 3.4 3 0 0 3 3 3 2 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 KEG13310.1 - 1.1e-11 45.1 0.1 3e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KEG13311.1 - 4.4e-15 55.9 0.0 1.2e-11 44.7 0.0 2.6 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal DUF563 PF04577.14 KEG13312.1 - 1.6e-16 61.1 0.1 3.7e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) EF1_GNE PF00736.19 KEG13313.1 - 5.1e-25 87.5 0.1 1.1e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_6 PF17171.4 KEG13313.1 - 0.0063 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sorting_nexin PF03700.13 KEG13313.1 - 0.019 15.5 12.2 1.2 9.7 3.4 2.3 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain DUF3140 PF11338.8 KEG13313.1 - 0.17 12.4 3.2 0.34 11.3 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) RNA_polI_A34 PF08208.11 KEG13313.1 - 0.18 11.9 5.8 0.24 11.5 5.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Metallophos PF00149.28 KEG13314.1 - 7.5e-31 108.2 0.0 9.5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEG13314.1 - 0.00065 20.1 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L13 PF00572.18 KEG13315.1 - 1.7e-05 25.1 4.1 0.00013 22.2 0.6 2.8 2 1 0 2 2 2 1 Ribosomal protein L13 zf_CCCH_4 PF18345.1 KEG13316.1 - 0.042 13.9 0.9 0.14 12.2 0.9 2.0 1 0 0 1 1 1 0 Zinc finger domain Amastin PF07344.11 KEG13318.1 - 7.9e-07 29.0 3.4 1.1e-06 28.6 3.4 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein HIG_1_N PF04588.13 KEG13318.1 - 0.005 17.0 4.7 0.86 9.9 0.1 2.7 3 0 0 3 3 3 2 Hypoxia induced protein conserved region Phage_holin_3_6 PF07332.11 KEG13318.1 - 2.8 8.0 6.0 0.97 9.5 0.3 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Methyltransf_15 PF09445.10 KEG13319.1 - 1.9e-30 105.6 0.0 2.5e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KEG13319.1 - 3e-11 43.9 0.1 5.8e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG13319.1 - 6.2e-10 39.1 0.1 7.7e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KEG13319.1 - 4.2e-09 36.4 0.0 6.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 tRNA_U5-meth_tr PF05958.11 KEG13319.1 - 5.3e-06 25.7 0.0 7.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 KEG13319.1 - 1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KEG13319.1 - 1.6e-05 25.5 0.2 3.2e-05 24.5 0.2 1.5 2 0 0 2 2 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KEG13319.1 - 0.00018 21.2 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KEG13319.1 - 0.00023 21.0 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KEG13319.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEG13319.1 - 0.0022 17.4 0.1 0.003 17.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KEG13319.1 - 0.0027 17.5 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DNA_methylase PF00145.17 KEG13319.1 - 0.0049 16.3 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_16 PF10294.9 KEG13319.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KEG13319.1 - 0.012 15.0 0.3 0.022 14.1 0.3 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KEG13319.1 - 0.013 15.1 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltr_RsmB-F PF01189.17 KEG13319.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KEG13319.1 - 0.018 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KEG13319.1 - 0.019 14.1 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KEG13319.1 - 0.068 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF5633 PF18656.1 KEG13319.1 - 0.088 12.7 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Methyltransf_3 PF01596.17 KEG13319.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Pox_MCEL PF03291.16 KEG13319.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_5 PF01795.19 KEG13319.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Methyltransf_31 PF13847.6 KEG13320.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LPD22 PF18834.1 KEG13320.1 - 0.14 12.3 0.9 0.39 11.0 0.7 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 Topo_C_assoc PF14370.6 KEG13321.1 - 0.088 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal topoisomerase domain AAA_22 PF13401.6 KEG13322.1 - 8.7e-08 32.5 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEG13322.1 - 3.4e-07 30.7 0.0 1.4e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG13322.1 - 0.00056 20.3 0.0 0.0027 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEG13322.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KEG13322.1 - 0.013 15.8 0.0 0.047 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEG13322.1 - 0.099 12.1 0.0 0.5 9.9 0.0 2.0 1 1 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KEG13322.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KEG13322.1 - 0.19 11.5 0.2 0.57 9.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain PPR PF01535.20 KEG13323.1 - 1.2e-11 44.1 1.0 0.0013 18.8 0.0 5.7 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 KEG13323.1 - 1.5e-09 37.9 0.4 0.019 15.2 0.0 5.0 3 1 2 5 5 5 4 PPR repeat family PPR_1 PF12854.7 KEG13323.1 - 8.6e-05 22.2 0.0 0.032 14.0 0.0 3.7 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 KEG13323.1 - 0.0053 16.2 0.6 0.0053 16.2 0.6 2.7 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP SUD-M PF11633.8 KEG13323.1 - 0.05 13.3 0.0 5 6.8 0.0 2.6 2 0 0 2 2 2 0 Single-stranded poly(A) binding domain Beach PF02138.18 KEG13324.1 - 2.4e-99 332.2 0.0 3.4e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KEG13324.1 - 2.5e-08 33.9 0.0 7.3e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KEG13324.1 - 0.027 15.3 1.4 12 6.9 0.1 3.5 2 0 0 2 2 2 0 WD domain, G-beta repeat DHHC PF01529.20 KEG13325.1 - 1.5e-29 102.8 12.6 3e-29 101.8 12.6 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3742 PF12553.8 KEG13325.1 - 0.05 13.7 0.6 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) NYD-SP28 PF14772.6 KEG13326.1 - 6.5e-20 71.1 10.3 6.5e-20 71.1 10.3 5.0 4 2 1 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 KEG13326.1 - 3.6e-05 23.8 2.4 3.6e-05 23.8 2.4 3.5 4 1 1 5 5 5 1 Sperm tail C-terminal domain NFRKB_winged PF14465.6 KEG13326.1 - 1.4 9.2 9.1 5.5 7.3 1.1 3.5 2 1 1 3 3 3 0 NFRKB Winged Helix-like FIST PF08495.10 KEG13327.1 - 0.039 14.0 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 FIST N domain Ank_2 PF12796.7 KEG13329.1 - 1.1e-07 32.3 1.7 5.1e-05 23.8 0.8 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) IQ PF00612.27 KEG13329.1 - 8.5e-07 28.2 13.9 0.00013 21.4 2.0 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif Ank_4 PF13637.6 KEG13329.1 - 1.2e-05 25.7 1.1 0.001 19.6 0.6 3.5 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEG13329.1 - 0.036 14.4 0.7 1.7 9.0 0.3 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 KEG13329.1 - 0.045 14.2 3.0 16 6.1 0.1 4.4 4 0 0 4 4 4 0 Ankyrin repeat DUF4293 PF14126.6 KEG13329.1 - 4 7.7 6.9 11 6.3 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) IQ PF00612.27 KEG13330.1 - 0.0058 16.3 0.1 0.034 13.9 0.0 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif Guanylate_cyc PF00211.20 KEG13331.1 - 8.6e-13 48.3 0.0 2.5e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Globin PF00042.22 KEG13331.1 - 2e-12 47.6 0.1 3.4e-06 27.6 0.0 3.0 2 1 0 2 2 2 2 Globin PLAC8 PF04749.17 KEG13332.1 - 0.045 14.7 33.9 0.067 14.2 33.9 1.4 1 1 0 1 1 1 0 PLAC8 family DUF747 PF05346.11 KEG13333.1 - 5.5e-74 249.5 5.6 7.8e-74 249.0 5.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family FH2 PF02181.23 KEG13334.1 - 5.7e-61 206.7 2.6 8.9e-60 202.8 0.2 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain DUF3361 PF11841.8 KEG13334.1 - 0.0074 16.2 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF5357 PF17310.2 KEG13334.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) V-SNARE PF05008.15 KEG13334.1 - 0.26 11.7 9.9 0.064 13.6 0.9 3.6 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus ATP-synt_D PF01813.17 KEG13334.1 - 0.33 10.8 5.5 0.78 9.5 0.4 2.9 3 0 0 3 3 3 0 ATP synthase subunit D DUF1751 PF08551.10 KEG13335.1 - 8.8e-05 23.0 6.3 0.00025 21.6 6.3 1.8 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KEG13335.1 - 0.26 11.3 13.1 0.021 14.8 7.8 2.0 2 1 0 2 2 2 0 Rhomboid family DUF1129 PF06570.11 KEG13335.1 - 0.49 9.8 3.0 1.7 8.1 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) CCB1 PF12046.8 KEG13335.1 - 6.5 6.1 14.5 0.82 9.0 3.9 3.1 3 1 0 3 3 3 0 Cofactor assembly of complex C subunit B PAD_porph PF04371.15 KEG13336.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 1 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase tRNA_Me_trans PF03054.16 KEG13337.1 - 6.7e-47 160.0 0.0 7.8e-37 126.9 0.0 3.3 2 2 1 3 3 3 3 tRNA methyl transferase Asn_synthase PF00733.21 KEG13337.1 - 0.0052 16.5 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Sec7 PF01369.20 KEG13338.1 - 9.8e-38 129.7 0.0 1.8e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain SUIM_assoc PF16619.5 KEG13338.1 - 0.27 11.3 11.2 1.2 9.3 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEG13338.1 - 5.9 6.4 13.5 10 5.6 0.2 2.6 2 0 0 2 2 2 0 Spt20 family EF-hand_7 PF13499.6 KEG13339.1 - 1.8e-22 79.6 0.1 4.7e-06 27.0 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 KEG13339.1 - 2e-22 77.0 5.2 3.4e-06 26.2 0.5 5.3 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KEG13339.1 - 3.2e-21 74.9 3.7 1.5e-06 28.0 0.0 4.8 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KEG13339.1 - 1.3e-19 68.4 5.3 0.00024 20.8 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KEG13339.1 - 2.1e-11 42.8 4.9 0.0048 16.3 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 KEG13339.1 - 0.0014 18.9 0.6 3.5 8.0 0.0 4.7 5 1 1 6 6 6 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KEG13339.1 - 0.012 15.9 0.0 0.21 11.9 0.0 2.6 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DDT PF02791.17 KEG13339.1 - 0.026 14.8 0.0 0.28 11.5 0.0 2.7 3 1 0 3 3 3 0 DDT domain EF-hand_4 PF12763.7 KEG13339.1 - 0.063 13.2 0.0 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand M16C_assoc PF08367.11 KEG13340.1 - 1.3e-30 106.4 0.0 2.6e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KEG13340.1 - 4.9e-26 91.9 0.1 4.4e-19 69.2 0.0 3.0 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEG13340.1 - 7e-12 45.6 0.7 8.2e-11 42.1 0.0 2.9 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) FAM131 PF15010.6 KEG13340.1 - 0.0079 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Putative cell signalling Cytochrom_C1 PF02167.15 KEG13343.1 - 1.2e-71 241.0 0.0 1.3e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Adaptin_N PF01602.20 KEG13344.1 - 6.5e-79 265.9 1.5 8.4e-79 265.5 1.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region VHL_C PF17211.3 KEG13344.1 - 0.068 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 VHL box domain HEAT PF02985.22 KEG13344.1 - 0.44 11.0 2.5 12 6.5 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Peptidase_M20 PF01546.28 KEG13346.1 - 4e-25 88.7 0.0 5.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEG13346.1 - 2.5e-18 66.0 0.0 3.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 KEG13346.1 - 0.024 13.7 0.0 0.069 12.2 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase GalKase_gal_bdg PF10509.9 KEG13347.1 - 9.2e-15 53.9 0.0 1.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KEG13347.1 - 2.4e-08 34.2 0.1 6.1e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KEG13347.1 - 4.4e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ribul_P_3_epim PF00834.19 KEG13348.1 - 7.8e-57 191.9 0.2 9.3e-57 191.6 0.2 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PEX11 PF05648.14 KEG13349.1 - 0.011 15.2 0.1 0.024 14.1 0.1 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 KEG13350.1 - 6.4e-12 45.4 0.0 1.5e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) zf-C3HC4_3 PF13920.6 KEG13351.1 - 1.9e-13 50.0 7.5 1.9e-13 50.0 7.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG13351.1 - 1.7e-06 28.2 6.8 1.7e-06 28.2 6.8 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KEG13351.1 - 2.7e-05 24.0 6.9 2.7e-05 24.0 6.9 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEG13351.1 - 6.2e-05 22.8 7.6 6.2e-05 22.8 7.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG13351.1 - 0.00033 20.4 9.0 0.00033 20.4 9.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG13351.1 - 0.00064 19.6 14.8 0.0069 16.3 13.7 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 KEG13351.1 - 0.47 10.3 12.3 2.9 7.7 7.1 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KEG13351.1 - 1.2 9.3 6.9 5.1 7.2 0.4 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 KEG13351.1 - 3.4 7.9 11.1 63 3.8 10.8 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger DnaJ_CXXCXGXG PF00684.19 KEG13351.1 - 4.5 7.7 10.2 11 6.5 6.9 2.1 1 1 1 2 2 2 0 DnaJ central domain PEX11 PF05648.14 KEG13352.1 - 2.1e-11 43.7 0.0 2.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) IKKbetaNEMObind PF12179.8 KEG13354.1 - 0.019 15.0 1.2 0.11 12.6 1.2 2.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain FGAR-AT_N PF18076.1 KEG13354.1 - 0.9 9.5 4.7 1.5 8.8 0.1 3.3 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Cullin PF00888.22 KEG13357.1 - 2.9e-13 49.3 0.0 2.9e-13 49.3 0.0 2.6 3 0 0 3 3 3 1 Cullin family ANAPC2 PF08672.11 KEG13357.1 - 0.055 14.0 2.3 0.2 12.2 0.8 2.8 2 1 1 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Ribosomal_L27A PF00828.19 KEG13358.1 - 2.7e-21 76.6 0.1 3.5e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L14 PF00238.19 KEG13359.1 - 2.1e-36 124.7 0.1 2.4e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS PF00989.25 KEG13359.1 - 0.19 11.7 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 PAS fold Takusan PF04822.13 KEG13361.1 - 0.0021 17.9 9.0 0.055 13.4 1.4 3.1 2 1 0 2 2 2 2 Takusan Spc42p PF11544.8 KEG13361.1 - 0.32 11.0 5.9 0.16 12.0 0.6 3.1 2 2 0 2 2 2 0 Spindle pole body component Spc42p SET PF00856.28 KEG13362.1 - 9.8e-05 22.8 0.0 0.00015 22.2 0.0 1.2 1 0 0 1 1 1 1 SET domain DNA_binding_1 PF01035.20 KEG13362.1 - 0.19 11.9 0.0 5.2 7.3 0.0 2.3 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Proteasome PF00227.26 KEG13363.1 - 3.7e-48 163.5 0.2 4.3e-48 163.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KEG13363.1 - 0.00039 19.8 2.3 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Ribosomal_S17 PF00366.20 KEG13364.1 - 2.6e-18 65.9 0.6 2.6e-18 65.9 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 Rubella_E1 PF05748.11 KEG13364.1 - 0.19 10.6 0.0 0.41 9.5 0.0 1.5 2 0 0 2 2 2 0 Rubella membrane glycoprotein E1 Cpn60_TCP1 PF00118.24 KEG13365.1 - 6.8e-159 529.6 1.4 8.6e-159 529.3 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.19 KEG13366.1 - 3.8e-33 114.4 0.0 1e-29 103.3 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 KEG13366.1 - 0.0032 17.3 0.1 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 DUF1126 PH-like domain WD40 PF00400.32 KEG13367.1 - 2.1e-26 91.6 15.3 7e-09 36.2 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 KEG13367.1 - 3.3e-11 43.3 6.4 5.7e-11 42.5 6.4 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KEG13367.1 - 1.7e-05 25.0 0.1 0.89 9.9 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEG13367.1 - 0.00065 19.6 0.1 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KEG13367.1 - 0.034 12.8 3.2 0.93 8.1 0.0 3.3 3 1 1 4 4 4 0 Nucleoporin Nup120/160 VapB_antitoxin PF09957.9 KEG13367.1 - 0.071 13.0 1.0 0.13 12.2 1.0 1.4 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB EF-hand_7 PF13499.6 KEG13368.1 - 1.1e-13 51.4 1.9 2e-07 31.3 0.8 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG13368.1 - 9.7e-10 37.3 3.8 4.8e-08 32.0 0.1 3.8 3 1 1 4 4 4 1 EF hand EF-hand_8 PF13833.6 KEG13368.1 - 1.3e-09 37.8 3.5 8.7e-07 28.7 0.2 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KEG13368.1 - 2.4e-09 36.3 0.2 3.6e-06 26.5 0.0 3.7 3 1 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KEG13368.1 - 0.00014 21.2 0.0 0.00014 21.2 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KEG13368.1 - 0.00018 21.8 0.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 KEG13368.1 - 0.0059 16.9 0.0 0.34 11.3 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 KEG13368.1 - 0.0081 17.0 0.0 0.011 16.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain UPF0154 PF03672.13 KEG13368.1 - 0.018 15.1 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Radical_SAM PF04055.21 KEG13368.1 - 0.068 13.5 0.1 0.095 13.1 0.1 1.2 1 0 0 1 1 1 0 Radical SAM superfamily PhetRS_B1 PF18262.1 KEG13368.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain CtsR_C PF17727.1 KEG13368.1 - 0.11 12.6 0.1 0.45 10.7 0.0 2.0 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain Type2_restr_D3 PF16902.5 KEG13369.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Endonuc-BglII PF09195.11 KEG13369.1 - 0.066 13.0 0.7 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Restriction endonuclease BglII Sterol_MT_C PF08498.10 KEG13370.1 - 3.5e-23 81.7 0.4 1.2e-22 80.0 0.2 2.0 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KEG13370.1 - 6e-15 55.7 0.1 2.2e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG13370.1 - 1.2e-12 48.3 0.0 6.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG13370.1 - 2.9e-10 40.2 0.0 5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG13370.1 - 3e-08 33.7 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEG13370.1 - 1.9e-07 30.6 0.0 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KEG13370.1 - 1.2e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEG13370.1 - 3.4e-06 27.7 0.1 6.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 KEG13370.1 - 0.11 12.0 0.3 0.16 11.5 0.3 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KEG13370.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEG13370.1 - 0.2 11.2 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Med3 PF11593.8 KEG13371.1 - 4.7e-05 22.8 0.4 8.1e-05 22.0 0.4 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF938 PF06080.12 KEG13373.1 - 4.6e-45 153.9 0.0 6e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KEG13373.1 - 0.00012 22.7 0.0 0.088 13.5 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEG13373.1 - 0.066 13.9 0.0 0.68 10.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.21 KEG13374.1 - 3.3e-65 220.7 0.0 3.7e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEG13374.1 - 0.04 12.4 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEG13374.1 - 0.047 13.0 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 KEG13374.1 - 0.12 11.1 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III adh_short PF00106.25 KEG13375.1 - 6.6e-21 74.7 0.0 1.5e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEG13375.1 - 7.7e-07 28.9 0.0 0.00088 18.9 0.0 2.7 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEG13375.1 - 0.00054 19.9 0.1 0.00097 19.1 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEG13375.1 - 0.0017 17.9 0.1 0.0046 16.4 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEG13375.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KEG13375.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Endonuclease_5 PF04493.14 KEG13376.1 - 7.9e-59 198.7 0.0 1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 KEG13376.1 - 0.0073 15.7 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF99 Glucokinase PF02685.16 KEG13377.1 - 3.6e-18 65.6 0.0 1.5e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 Glucokinase ROK PF00480.20 KEG13377.1 - 3.7e-07 29.9 0.0 5.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ROK family Ribosomal_S18 PF01084.20 KEG13378.1 - 0.00037 20.7 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 KAR PF15222.6 KEG13379.1 - 0.047 14.0 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Kidney androgen-regulated DUF2052 PF09747.9 KEG13379.1 - 0.13 12.3 14.2 0.25 11.5 14.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TPR_2 PF07719.17 KEG13380.1 - 4.7e-35 116.9 2.3 0.00056 19.8 0.0 9.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13380.1 - 4.1e-34 115.0 2.6 3.8e-05 23.3 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13380.1 - 4.8e-28 95.0 3.1 0.00062 19.8 0.0 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13380.1 - 8.9e-21 74.0 10.4 9.7e-05 22.6 0.0 7.4 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13380.1 - 2.8e-19 68.5 0.0 2.1e-07 30.5 0.0 6.7 6 1 1 7 7 7 3 TPR repeat TPR_19 PF14559.6 KEG13380.1 - 1e-17 64.3 0.7 0.00061 20.2 0.0 5.9 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13380.1 - 1.1e-16 61.1 1.5 0.0085 16.7 0.0 6.5 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEG13380.1 - 2.4e-14 52.2 0.2 0.0046 16.9 0.0 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13380.1 - 2.8e-14 52.6 5.9 0.00035 21.2 0.0 7.6 5 3 3 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13380.1 - 4.6e-14 52.3 0.4 0.0004 20.5 0.0 5.0 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEG13380.1 - 2.6e-12 46.5 7.0 0.17 12.6 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13380.1 - 5.7e-12 45.7 11.7 2.2e-05 24.6 0.0 5.5 1 1 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEG13380.1 - 7.3e-08 32.3 8.9 0.0025 18.1 0.0 6.8 8 1 0 8 8 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEG13380.1 - 4.3e-06 26.4 4.9 0.28 11.1 0.0 6.9 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEG13380.1 - 7.5e-06 25.4 0.4 0.22 10.7 0.0 4.1 1 1 4 5 5 5 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KEG13380.1 - 4.1e-05 22.5 0.0 0.2 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 KEG13380.1 - 0.0024 18.2 3.1 19 5.6 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KEG13380.1 - 0.012 15.1 0.2 1.5 8.2 0.1 3.4 2 1 2 4 4 4 0 Coatomer epsilon subunit Paf67 PF10255.9 KEG13380.1 - 0.029 13.4 4.4 0.058 12.4 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 MIT PF04212.18 KEG13380.1 - 0.044 13.9 0.1 4.3 7.5 0.2 3.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 KEG13380.1 - 0.063 12.3 0.1 0.49 9.3 0.0 2.0 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Stk19 PF10494.9 KEG13380.1 - 0.14 11.9 0.1 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 DUF410 PF04190.13 KEG13381.1 - 0.00076 19.4 0.1 0.0014 18.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF410) Guanylate_kin PF00625.21 KEG13382.1 - 1.1e-36 126.2 0.0 2e-23 83.0 0.0 2.6 2 1 0 2 2 2 2 Guanylate kinase AAA_33 PF13671.6 KEG13382.1 - 8.5e-07 29.2 0.2 1.9e-05 24.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KEG13382.1 - 9.2e-07 28.9 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG13382.1 - 4e-06 26.8 0.0 9.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KEG13382.1 - 1.4e-05 25.5 0.0 3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEG13382.1 - 6.9e-05 23.1 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KEG13382.1 - 0.00025 21.6 0.0 0.00041 20.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KEG13382.1 - 0.00089 19.8 0.2 0.023 15.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEG13382.1 - 0.0013 18.5 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEG13382.1 - 0.0015 18.9 0.1 0.0061 16.9 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KEG13382.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KEG13382.1 - 0.0019 18.3 0.0 0.0022 18.1 0.0 1.4 1 1 0 1 1 1 1 Dynamin family cobW PF02492.19 KEG13382.1 - 0.0034 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEG13382.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KEG13382.1 - 0.0077 16.5 0.1 0.029 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEG13382.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KEG13382.1 - 0.02 14.9 0.0 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KEG13382.1 - 0.025 15.1 0.5 0.077 13.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 KEG13382.1 - 0.042 13.1 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KEG13382.1 - 0.06 13.2 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea dNK PF01712.19 KEG13382.1 - 0.076 12.9 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase NB-ARC PF00931.22 KEG13382.1 - 0.089 12.0 0.0 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 KEG13382.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Roc PF08477.13 KEG13382.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KEG13382.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KEG13382.1 - 0.18 12.2 0.1 1.9 8.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1_Xtn PF16897.5 KEG13383.1 - 4e-42 142.5 0.0 8e-42 141.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KEG13383.1 - 1.6e-19 70.0 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KEG13383.1 - 9.1e-19 67.3 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KEG13383.1 - 1e-09 38.1 0.0 4.7e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KEG13383.1 - 0.004 16.2 0.1 0.014 14.4 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KEG13383.1 - 0.0078 15.8 0.3 11 5.5 0.0 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEG13383.1 - 0.024 14.7 0.1 2.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 KEG13383.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KEG13383.1 - 0.13 12.1 0.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KEG13383.1 - 0.18 12.0 0.2 0.32 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain GCP_N_terminal PF17681.1 KEG13384.1 - 5.9e-14 52.4 0.0 2e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Sec1 PF00995.23 KEG13385.1 - 1.7e-93 314.8 0.0 2.1e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family BRCT PF00533.26 KEG13386.1 - 7e-06 26.3 0.1 1.8e-05 25.0 0.0 1.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KEG13386.1 - 7e-06 25.9 0.2 5.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 KEG13386.1 - 0.063 13.7 0.0 0.27 11.7 0.0 1.9 2 1 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF1067 PF06362.11 KEG13387.1 - 0.024 15.4 0.2 0.059 14.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) PAP_assoc PF03828.19 KEG13388.1 - 4.8e-06 26.7 0.1 1.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase SUIM_assoc PF16619.5 KEG13388.1 - 0.004 17.2 0.9 0.004 17.2 0.9 9.0 6 2 1 7 7 7 2 Unstructured region C-term to UIM in Ataxin3 DUF2423 PF10338.9 KEG13389.1 - 0.0053 17.0 5.1 0.0053 17.0 5.1 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2423) Menin PF05053.13 KEG13389.1 - 0.0061 15.0 5.2 0.008 14.6 5.2 1.1 1 0 0 1 1 1 1 Menin SurA_N_2 PF13623.6 KEG13389.1 - 0.0088 15.9 2.9 0.017 15.0 2.9 1.4 1 0 0 1 1 1 1 SurA N-terminal domain SurA_N_3 PF13624.6 KEG13389.1 - 0.012 15.4 0.4 0.022 14.5 0.4 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Arf PF00025.21 KEG13390.1 - 3.4e-65 218.8 0.0 3.8e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEG13390.1 - 1.7e-16 60.5 0.1 2.2e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEG13390.1 - 6.3e-14 51.8 0.0 7.6e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEG13390.1 - 9.8e-14 51.3 0.2 1.1e-10 41.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KEG13390.1 - 4.5e-12 45.9 0.0 5.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEG13390.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG13390.1 - 1.5e-06 28.3 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KEG13390.1 - 0.0059 15.9 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 KEG13390.1 - 0.047 13.8 0.1 0.074 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain CENP-M PF11111.8 KEG13390.1 - 0.13 11.5 0.0 8.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 KEG13390.1 - 0.13 11.8 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 KEG13390.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.6 1 1 0 1 1 1 0 Adenylylsulphate kinase Ribosomal_L5_C PF00673.21 KEG13391.1 - 1.2e-20 73.5 0.0 2.4e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KEG13391.1 - 5.9e-17 61.7 0.2 1.3e-15 57.5 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 N_Asn_amidohyd PF14736.6 KEG13393.1 - 0.00081 18.6 0.1 0.0086 15.3 0.0 2.2 2 0 0 2 2 2 1 Protein N-terminal asparagine amidohydrolase Lyase_1 PF00206.20 KEG13394.1 - 1.3e-49 169.3 0.0 1.9e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 KEG13394.1 - 2e-44 150.3 0.0 4.2e-44 149.3 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Peptidase_C2 PF00648.21 KEG13395.1 - 1.3e-59 201.6 0.0 2e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 KEG13395.1 - 2.1e-34 118.0 0.4 8e-34 116.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Lectin_C PF00059.21 KEG13396.1 - 1.2e-08 35.7 0.0 0.00057 20.6 0.0 3.2 3 1 0 3 3 3 2 Lectin C-type domain TPR_2 PF07719.17 KEG13397.1 - 5.4e-10 38.6 3.3 0.00031 20.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13397.1 - 1e-06 28.4 0.7 0.00067 19.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13397.1 - 8.2e-06 26.2 16.3 0.048 14.5 1.1 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEG13397.1 - 0.00033 20.5 2.4 5.4 7.3 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13397.1 - 0.0019 18.4 7.7 0.53 10.6 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13397.1 - 0.0022 18.6 25.9 0.85 10.3 1.3 5.4 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13397.1 - 0.0093 15.6 6.1 0.069 12.8 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 KEG13397.1 - 0.034 14.0 7.4 0.27 11.1 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13397.1 - 0.53 10.5 15.8 13 6.0 0.1 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat SNAP PF14938.6 KEG13397.1 - 0.9 8.9 9.8 36 3.6 9.4 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 KEG13397.1 - 1.7 8.3 12.0 0.36 10.5 0.2 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KEG13397.1 - 2.1 9.1 0.0 2.1 9.1 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG13397.1 - 3.8 7.5 6.3 2.9 7.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S13_N PF08069.12 KEG13400.1 - 0.42 10.7 1.3 2 8.5 0.4 2.2 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain ETF PF01012.21 KEG13402.1 - 6e-42 143.6 0.6 7.2e-42 143.3 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PIG-L PF02585.17 KEG13402.1 - 0.016 15.9 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase GTP_EFTU PF00009.27 KEG13403.1 - 8.7e-50 169.0 0.0 1.7e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEG13403.1 - 1.9e-14 53.4 0.0 4.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KEG13403.1 - 3.9e-05 23.7 0.1 8.1e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KEG13403.1 - 0.0025 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU_D2 PF03144.25 KEG13403.1 - 0.014 15.8 0.9 0.044 14.2 0.9 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF2293 PF10056.9 KEG13403.1 - 0.085 13.1 0.8 0.22 11.8 0.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) EFG_II PF14492.6 KEG13403.1 - 0.13 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II RNA_pol_Rpb6 PF01192.22 KEG13404.1 - 1.4e-10 40.9 0.0 2.8e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb6 Spc7 PF08317.11 KEG13406.1 - 0.0014 17.6 4.5 0.0014 17.6 4.5 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 KEG13406.1 - 0.0019 17.9 3.8 0.003 17.3 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF745) Filament PF00038.21 KEG13406.1 - 0.0043 16.7 14.8 0.047 13.3 14.8 2.0 1 1 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 KEG13406.1 - 0.0043 17.1 1.9 0.13 12.3 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 KEG13406.1 - 0.015 15.6 1.4 0.65 10.3 0.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MbeD_MobD PF04899.12 KEG13406.1 - 0.015 15.4 11.3 5.8 7.1 0.7 4.3 3 1 1 4 4 4 0 MbeD/MobD like Laminin_I PF06008.14 KEG13406.1 - 0.017 14.9 8.3 0.25 11.0 3.6 2.6 2 1 1 3 3 3 0 Laminin Domain I MAD PF05557.13 KEG13406.1 - 0.027 12.9 10.2 0.19 10.1 3.4 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Laminin_II PF06009.12 KEG13406.1 - 0.061 13.3 2.5 0.081 12.9 0.7 2.0 2 0 0 2 2 2 0 Laminin Domain II Taxilin PF09728.9 KEG13406.1 - 0.063 12.4 4.9 0.11 11.7 4.9 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein COG2 PF06148.11 KEG13406.1 - 0.09 12.9 3.4 0.12 12.4 1.6 2.1 2 1 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 KEG13406.1 - 0.1 11.2 1.2 0.13 10.8 1.2 1.1 1 0 0 1 1 1 0 AAA domain YkyA PF10368.9 KEG13406.1 - 0.11 12.1 0.8 0.24 11.1 0.3 1.7 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein FlaC_arch PF05377.11 KEG13406.1 - 0.16 12.4 1.8 1.6 9.2 0.3 3.0 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF713 PF05218.14 KEG13406.1 - 0.17 11.6 1.8 0.26 11.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) HMMR_N PF15905.5 KEG13406.1 - 0.22 11.0 6.3 0.44 10.0 6.3 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cnn_1N PF07989.11 KEG13406.1 - 0.24 11.6 8.6 0.14 12.4 2.1 2.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 WXG100 PF06013.12 KEG13406.1 - 0.24 11.6 1.9 2.5 8.4 0.0 2.7 3 0 0 3 3 2 0 Proteins of 100 residues with WXG GOLGA2L5 PF15070.6 KEG13406.1 - 0.25 10.0 10.7 0.19 10.4 7.8 1.9 2 1 1 3 3 3 0 Putative golgin subfamily A member 2-like protein 5 Exonuc_VII_L PF02601.15 KEG13406.1 - 0.27 10.8 5.5 0.43 10.1 5.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 KEG13406.1 - 0.31 10.9 11.7 0.94 9.3 0.5 3.7 4 0 0 4 4 4 0 Septum formation initiator TMF_TATA_bd PF12325.8 KEG13406.1 - 0.31 11.3 13.1 0.25 11.5 6.7 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SHE3 PF17078.5 KEG13406.1 - 0.31 10.7 4.1 0.24 11.1 1.8 1.8 2 1 0 2 2 1 0 SWI5-dependent HO expression protein 3 Sipho_Gp157 PF05565.11 KEG13406.1 - 0.34 10.9 3.7 14 5.6 0.3 2.9 1 1 2 3 3 3 0 Siphovirus Gp157 HIP1_clath_bdg PF16515.5 KEG13406.1 - 0.42 11.2 8.9 1.5 9.5 0.8 3.1 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 KEG13406.1 - 0.49 10.4 11.6 0.086 12.9 5.5 2.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 KEG13406.1 - 0.53 10.3 10.1 5.3 7.1 0.0 4.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 KEG13406.1 - 0.61 10.5 9.7 0.2 12.0 5.3 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MscS_porin PF12795.7 KEG13406.1 - 0.91 9.0 12.4 0.47 10.0 6.8 2.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.7 KEG13406.1 - 0.93 9.6 12.7 0.4 10.8 9.0 2.1 2 1 0 2 2 2 0 Tropomyosin like ATG16 PF08614.11 KEG13406.1 - 0.94 9.7 17.4 0.19 11.9 9.9 2.4 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 KEG13406.1 - 0.95 9.6 9.2 0.62 10.2 2.4 2.9 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 KEG13406.1 - 0.99 10.1 9.9 7.1 7.3 0.5 4.0 2 1 1 3 3 3 0 SlyX ADIP PF11559.8 KEG13406.1 - 1.1 9.4 12.0 0.23 11.6 6.3 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KEG13406.1 - 1.2 9.8 6.5 4 8.1 1.0 3.1 2 1 2 4 4 4 0 Initiation control protein YabA IFT57 PF10498.9 KEG13406.1 - 1.2 8.0 6.3 0.4 9.6 2.7 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 CCDC-167 PF15188.6 KEG13406.1 - 1.3 9.5 7.9 0.11 12.8 1.6 2.4 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 Nup54 PF13874.6 KEG13406.1 - 1.4 9.0 11.0 13 5.8 7.1 2.9 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.9 KEG13406.1 - 1.5 9.1 13.0 0.82 9.9 5.7 2.8 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.6 KEG13406.1 - 1.5 9.3 8.8 0.32 11.4 3.1 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) Rho_Binding PF08912.11 KEG13406.1 - 1.5 9.7 9.5 7.5 7.4 1.2 3.8 2 1 1 3 3 3 0 Rho Binding ERM PF00769.19 KEG13406.1 - 2 8.2 11.4 13 5.5 7.8 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.6 KEG13406.1 - 2.8 7.2 8.7 1.7 7.9 4.8 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KEG13406.1 - 3.3 8.3 13.6 2.5 8.6 9.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KEG13406.1 - 4.4 8.3 10.4 2.4 9.1 5.1 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KEG13406.1 - 7.5 7.0 13.0 3.1 8.2 5.3 3.3 2 1 0 3 3 3 0 Centromere protein H (CENP-H) CPSF100_C PF13299.6 KEG13407.1 - 3.3e-21 76.2 0.0 7.1e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_6 PF16661.5 KEG13407.1 - 4.1e-16 59.0 0.0 6.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KEG13407.1 - 0.007 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain CHMI PF02962.15 KEG13408.1 - 0.041 14.2 0.0 4.8 7.5 0.0 3.0 2 0 0 2 2 2 0 5-carboxymethyl-2-hydroxymuconate isomerase Peptidase_C12 PF01088.21 KEG13409.1 - 1.1e-50 172.4 0.0 1.7e-50 171.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40_3 PF15911.5 KEG13410.1 - 8.3e-13 48.1 0.1 2.1e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Clathrin PF00637.20 KEG13410.1 - 3e-08 33.7 3.7 0.041 13.8 0.2 4.9 3 2 2 5 5 5 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KEG13410.1 - 2.4e-06 27.8 0.0 1.6 9.1 0.0 4.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KEG13410.1 - 0.012 16.4 5.0 1.8 9.6 0.1 5.6 6 1 1 7 7 4 0 Tetratricopeptide repeat MIT PF04212.18 KEG13410.1 - 0.13 12.4 11.8 5.1 7.2 0.5 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DZR PF12773.7 KEG13410.1 - 0.17 12.0 7.6 2.6 8.2 7.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon TPR_7 PF13176.6 KEG13410.1 - 0.27 11.4 6.1 16 5.8 0.2 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KEG13410.1 - 0.58 10.1 7.4 3.1 7.8 0.2 3.3 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Stc1 PF12898.7 KEG13410.1 - 2.1 8.9 8.5 0.26 11.9 3.9 1.9 2 0 0 2 2 1 0 Stc1 domain zf-RING_4 PF14570.6 KEG13410.1 - 2.3 8.1 10.4 3.3 7.6 8.5 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KEG13410.1 - 2.6 8.0 5.7 37 4.3 0.5 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 TPR_11 PF13414.6 KEG13410.1 - 7.7 6.3 7.6 90 2.9 0.3 4.5 4 0 0 4 4 4 0 TPR repeat Mito_carr PF00153.27 KEG13411.1 - 2.3e-56 187.7 0.2 6.6e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GAGA PF09237.11 KEG13412.1 - 0.25 11.2 1.2 0.57 10.0 1.2 1.5 1 0 0 1 1 1 0 GAGA factor DSPc PF00782.20 KEG13413.1 - 1e-13 51.2 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG13413.1 - 0.072 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KEG13413.1 - 0.095 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KEG13413.1 - 0.17 11.5 0.3 0.4 10.2 0.1 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KEG13413.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Bud13 PF09736.9 KEG13414.1 - 4.8e-06 27.0 0.2 8.7e-06 26.2 0.2 1.4 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex CCDC92 PF14916.6 KEG13415.1 - 0.0014 18.3 0.2 0.0014 18.3 0.2 2.7 2 0 0 2 2 2 1 Coiled-coil domain of unknown function ELYS-bb PF16687.5 KEG13415.1 - 0.21 10.2 0.6 0.33 9.5 0.6 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin PKcGMP_CC PF16808.5 KEG13415.1 - 0.91 9.4 7.3 0.98 9.3 1.5 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_M3_N PF08439.10 KEG13415.1 - 1.7 9.0 5.2 7.6 6.9 0.8 3.6 3 0 0 3 3 3 0 Oligopeptidase F DUF1796 PF08795.10 KEG13415.1 - 1.8 8.5 6.7 0.36 10.8 0.9 2.6 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) AAA_lid_2 PF17863.1 KEG13416.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA lid domain Presenilin PF01080.17 KEG13417.1 - 1.5 7.5 7.2 1.6 7.4 7.2 1.0 1 0 0 1 1 1 0 Presenilin PDEase_I PF00233.19 KEG13418.1 - 1.6e-23 83.7 0.0 2.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Rhodanese PF00581.20 KEG13420.1 - 0.0048 17.4 0.0 0.0081 16.7 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain PDE8 PF08629.10 KEG13421.1 - 9.2 6.3 6.4 4.1 7.5 1.0 2.4 2 0 0 2 2 2 0 PDE8 phosphodiesterase Topo_C_assoc PF14370.6 KEG13422.1 - 3.1e-28 97.5 0.1 5.1e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain Macoilin PF09726.9 KEG13422.1 - 0.0056 15.3 7.2 0.0061 15.2 7.2 1.1 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 KEG13422.1 - 0.03 14.3 11.4 0.036 14.0 11.4 1.2 1 0 0 1 1 1 0 SPX domain MMU163 PF17119.5 KEG13422.1 - 0.055 12.6 2.8 0.094 11.9 2.8 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Ndc1_Nup PF09531.10 KEG13422.1 - 0.072 11.8 3.4 0.08 11.6 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 KEG13422.1 - 0.15 10.5 4.6 0.17 10.4 4.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.9 KEG13422.1 - 0.2 10.5 10.3 0.22 10.3 10.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 KEG13422.1 - 0.26 9.5 10.6 0.34 9.1 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.6 KEG13422.1 - 0.29 11.8 5.0 0.42 11.3 5.0 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Menin PF05053.13 KEG13422.1 - 0.36 9.1 5.9 0.46 8.8 5.9 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 KEG13422.1 - 2.3 6.9 4.2 2.5 6.8 4.2 1.1 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 KEG13422.1 - 6.3 4.4 6.8 6.8 4.3 6.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3827 PF12877.7 KEG13422.1 - 6.5 5.0 12.0 8.8 4.6 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Nodulin-like PF06813.13 KEG13423.1 - 4.3e-09 36.2 28.8 3.2e-08 33.4 28.8 2.2 1 1 0 1 1 1 1 Nodulin-like DUF4834 PF16118.5 KEG13423.1 - 1.1 10.3 5.3 4.8 8.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Methyltransf_25 PF13649.6 KEG13425.1 - 4.8e-06 27.2 0.0 8.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG13425.1 - 9.3e-06 25.5 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG13425.1 - 0.0005 20.8 0.0 0.00082 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF737 PF05300.11 KEG13426.1 - 0.021 15.2 4.8 0.03 14.7 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CENP-F_leu_zip PF10473.9 KEG13426.1 - 0.022 14.8 1.5 0.036 14.1 1.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PLU-1 PF08429.11 KEG13429.1 - 0.11 11.6 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 PLU-1-like protein DUF148 PF02520.17 KEG13429.1 - 0.18 11.9 2.3 0.23 11.6 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function DUF148 TetR_C_24 PF17932.1 KEG13429.1 - 0.34 11.2 5.2 0.24 11.7 0.4 3.0 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DivIVA PF05103.13 KEG13430.1 - 0.04 14.0 19.9 2 8.5 0.1 2.6 2 0 0 2 2 2 0 DivIVA protein DUF1811 PF08838.10 KEG13430.1 - 0.49 10.7 0.1 0.49 10.7 0.1 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1811) DUF4140 PF13600.6 KEG13430.1 - 3.9 8.0 26.6 12 6.4 6.4 4.1 3 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) KH_6 PF15985.5 KEG13431.1 - 8.7e-13 48.4 0.2 1.4e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 KH domain GAS2 PF02187.17 KEG13433.1 - 0.11 12.6 0.4 0.46 10.6 0.4 2.0 1 1 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain CAP_N PF01213.19 KEG13434.1 - 0.019 14.4 7.4 0.02 14.4 7.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KEG13434.1 - 0.98 9.5 5.6 1.2 9.1 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator GRAM PF02893.20 KEG13435.1 - 2.4e-07 30.6 0.0 1.9e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 GRAM domain STAG PF08514.11 KEG13435.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 STAG domain GTP_EFTU PF00009.27 KEG13437.1 - 3.4e-64 216.0 0.3 4e-64 215.7 0.3 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG13437.1 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Asp_protease PF09668.10 KEG13437.1 - 0.0018 18.1 0.2 0.54 10.1 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease SRPRB PF09439.10 KEG13437.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_IV PF03764.18 KEG13438.1 - 4.8e-28 97.4 0.1 1.1e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KEG13438.1 - 1.8e-20 72.8 0.0 4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KEG13438.1 - 6.7e-14 51.7 0.0 1.8e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KEG13438.1 - 1.5e-13 50.9 0.1 3.9e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 P21-Arc PF04062.14 KEG13440.1 - 4e-44 150.7 0.0 4.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF2225 PF09986.9 KEG13440.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) His_Phos_1 PF00300.22 KEG13442.1 - 1.1e-27 97.0 0.0 5.3e-27 94.8 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 KEG13443.1 - 1.3e-05 24.7 0.0 4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13443.1 - 0.11 11.8 0.0 20 4.4 0.0 2.7 3 0 0 3 3 3 0 Protein tyrosine kinase PUB PF09409.10 KEG13444.1 - 5.3e-14 51.9 0.0 1.5e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 PUB domain zf-C2H2_assoc PF16606.5 KEG13444.1 - 0.33 11.2 2.7 0.34 11.2 0.8 2.1 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Pox_MCEL PF03291.16 KEG13445.1 - 5.4e-33 114.5 0.1 1.2e-24 87.1 0.1 2.1 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KEG13445.1 - 0.0011 19.7 0.2 0.0061 17.2 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG13445.1 - 0.0019 18.9 0.0 0.0031 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KEG13445.1 - 0.016 14.4 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family IMS PF00817.20 KEG13447.1 - 3.2e-38 131.1 0.3 6e-38 130.2 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 KEG13447.1 - 0.0044 17.3 0.0 0.064 13.6 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif DUF844 PF05815.11 KEG13447.1 - 0.049 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) mCpol PF18182.1 KEG13447.1 - 0.073 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 minimal CRISPR polymerase domain LCM PF04072.14 KEG13449.1 - 1.2e-25 90.6 0.0 3.9e-25 88.9 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TPR_1 PF00515.28 KEG13450.1 - 2.3e-41 138.0 11.6 1.9e-08 33.7 0.0 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13450.1 - 2.8e-34 114.4 6.9 1e-06 28.4 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13450.1 - 6.5e-18 63.4 8.6 0.00022 21.2 0.0 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13450.1 - 4.1e-17 61.6 9.2 5.4e-05 22.8 0.5 5.8 4 3 1 5 5 5 4 TPR repeat TPR_12 PF13424.6 KEG13450.1 - 4e-16 59.1 5.7 0.00015 22.0 0.2 4.5 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13450.1 - 2.3e-13 50.1 0.0 5.2e-05 23.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13450.1 - 1e-12 47.7 0.1 0.0012 19.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG13450.1 - 1.5e-12 46.6 1.0 0.22 11.7 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG13450.1 - 9.6e-11 42.0 8.6 0.0028 18.1 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13450.1 - 3.2e-10 40.5 2.6 0.025 15.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG13450.1 - 3.7e-09 36.6 0.2 0.015 15.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG13450.1 - 9.6e-09 35.0 4.6 0.057 13.8 0.4 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13450.1 - 1.5e-08 34.7 5.6 0.0041 17.3 0.0 2.7 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KEG13450.1 - 1.2e-07 31.7 9.5 0.31 11.1 0.1 4.8 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KEG13450.1 - 7.2e-06 26.1 2.0 0.1 12.7 0.0 4.2 3 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) SPO22 PF08631.10 KEG13450.1 - 8.4e-05 22.2 3.0 0.16 11.5 0.1 3.0 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like SHNi-TPR PF10516.9 KEG13450.1 - 8.4e-05 21.9 0.0 1.3 8.5 0.0 4.9 6 0 0 6 6 6 1 SHNi-TPR TPR_15 PF13429.6 KEG13450.1 - 0.00019 20.8 1.7 0.54 9.4 0.1 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 KEG13450.1 - 0.00025 20.9 1.3 2.5 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG13450.1 - 0.00035 20.6 2.1 0.024 14.7 0.1 4.0 5 1 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KEG13450.1 - 0.00068 19.4 6.7 1.4 8.9 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 KEG13450.1 - 0.0021 17.8 7.1 0.0036 17.0 3.4 2.7 2 1 1 3 3 3 1 26S proteasome subunit RPN7 Sel1 PF08238.12 KEG13450.1 - 0.0038 17.8 3.2 3.8 8.3 0.2 3.7 2 1 1 3 3 3 1 Sel1 repeat TPR_21 PF09976.9 KEG13450.1 - 0.02 14.6 1.9 0.25 11.0 0.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TOM20_plant PF06552.12 KEG13450.1 - 0.2 11.4 3.6 0.4 10.4 0.4 2.7 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF5113 PF17140.4 KEG13450.1 - 1.9 8.3 6.9 21 4.9 1.7 4.0 3 2 1 4 4 3 0 Domain of unknown function (DUF5113) SAP PF02037.27 KEG13451.1 - 2.1e-09 36.9 0.2 3.4e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 SAP domain FGGY_C PF02782.16 KEG13452.1 - 1.2e-39 136.1 0.1 2e-39 135.4 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEG13452.1 - 8.2e-10 38.6 0.0 5.8e-09 35.9 0.0 2.4 3 1 0 3 3 3 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KEG13452.1 - 0.0098 15.4 0.0 0.069 12.6 0.1 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PUF PF00806.19 KEG13453.1 - 7.1e-38 126.2 7.8 1.9e-07 30.4 0.1 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Ku_PK_bind PF08785.11 KEG13453.1 - 0.0009 19.4 0.5 0.37 10.9 0.0 3.8 3 1 1 4 4 4 1 Ku C terminal domain like FlxA PF14282.6 KEG13453.1 - 0.063 13.3 4.1 0.46 10.5 0.1 2.7 2 0 0 2 2 2 0 FlxA-like protein NLRC4_HD PF17889.1 KEG13453.1 - 0.13 12.6 0.9 27 5.2 0.1 3.7 3 0 0 3 3 3 0 NLRC4 helical domain ANAPC4 PF12896.7 KEG13453.1 - 1.2 8.5 4.1 2.9 7.3 0.1 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 YhzD PF14120.6 KEG13454.1 - 0.091 12.9 0.1 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 YhzD-like protein RHSP PF07999.11 KEG13455.1 - 3.6e-66 223.8 0.3 4.6e-66 223.5 0.3 1.1 1 0 0 1 1 1 1 Retrotransposon hot spot protein Snf7 PF03357.21 KEG13456.1 - 8.4e-36 123.2 16.2 9.8e-36 122.9 16.2 1.0 1 0 0 1 1 1 1 Snf7 DUF713 PF05218.14 KEG13456.1 - 0.013 15.3 5.0 0.04 13.7 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF713) WEMBL PF05701.11 KEG13456.1 - 0.014 14.1 10.2 0.018 13.8 10.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Dak2 PF02734.17 KEG13456.1 - 0.027 14.4 1.0 0.044 13.7 1.0 1.3 1 0 0 1 1 1 0 DAK2 domain RE_Bsp6I PF09504.10 KEG13456.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Bsp6I restriction endonuclease NPV_P10 PF05531.12 KEG13456.1 - 0.038 14.5 3.3 0.14 12.6 1.3 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5446 PF17522.2 KEG13456.1 - 0.06 13.5 0.4 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) LodA_N PF17990.1 KEG13456.1 - 0.28 11.1 2.1 0.3 11.0 1.1 1.5 1 1 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal DUF1319 PF07028.11 KEG13456.1 - 0.36 11.1 6.0 0.27 11.5 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) XRN_M PF17846.1 KEG13456.1 - 0.47 9.4 7.8 0.6 9.0 7.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Spc7 PF08317.11 KEG13456.1 - 0.48 9.2 14.4 0.65 8.8 14.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KEG13456.1 - 0.77 9.3 7.8 0.94 9.0 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KEG13456.1 - 5.6 6.0 10.0 7.5 5.5 10.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L18A PF01775.17 KEG13458.1 - 3.1e-39 133.8 0.6 4.6e-39 133.3 0.6 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CTP_transf_like PF01467.26 KEG13459.1 - 6.2e-43 146.4 0.0 5.5e-22 78.5 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KEG13459.1 - 0.00019 21.4 1.0 0.35 10.8 0.0 3.2 3 0 0 3 3 3 2 FAD synthetase DUF5639 PF18690.1 KEG13459.1 - 0.0078 16.4 0.1 6.8 6.9 0.0 2.7 3 0 0 3 3 3 2 Family of unknown function (DUF5639) Neuroparsin PF07327.11 KEG13459.1 - 0.11 13.0 0.7 0.5 10.8 0.2 2.3 2 1 1 3 3 3 0 Neuroparsin APG6_N PF17675.1 KEG13460.1 - 0.056 14.0 2.5 0.056 14.0 2.5 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Abhydrolase_6 PF12697.7 KEG13461.1 - 1.6e-21 78.0 2.1 2.1e-21 77.6 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEG13461.1 - 3.3e-09 36.4 0.9 4.3e-07 29.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG13461.1 - 4.6e-06 26.5 0.2 1.2e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KEG13461.1 - 3.8e-05 23.7 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEG13461.1 - 0.00071 19.1 0.1 0.0019 17.7 0.1 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KEG13461.1 - 0.00095 18.1 0.2 0.0039 16.1 0.2 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 KEG13461.1 - 0.043 13.9 0.1 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_9 PF10081.9 KEG13461.1 - 0.054 12.6 0.0 0.1 11.6 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta-hydrolase family Ser_hydrolase PF06821.13 KEG13461.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 KEG13461.1 - 0.069 12.9 0.9 0.33 10.6 0.9 1.9 1 1 0 1 1 1 0 PGAP1-like protein TP53IP5 PF15331.6 KEG13461.1 - 0.085 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Lipase_3 PF01764.25 KEG13461.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KEG13461.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 KEG13461.1 - 0.17 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II V_ATPase_I PF01496.19 KEG13462.1 - 3.1e-186 620.8 0.0 9.1e-186 619.3 0.0 1.6 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Dynamitin PF04912.14 KEG13462.1 - 0.09 12.1 2.8 0.65 9.3 2.9 2.0 1 1 1 2 2 2 0 Dynamitin UPF0184 PF03670.13 KEG13462.1 - 0.099 13.0 2.3 1.3 9.5 0.4 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) DAO PF01266.24 KEG13464.1 - 3.5e-06 26.8 0.2 0.00091 18.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEG13464.1 - 4.3e-05 23.7 0.1 0.00015 21.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KEG13464.1 - 0.00014 21.3 0.1 1.4 8.3 0.0 3.2 2 1 0 3 3 3 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEG13464.1 - 0.00046 19.5 0.2 0.0011 18.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEG13464.1 - 0.0016 17.8 0.1 0.0028 16.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KEG13464.1 - 0.0031 16.6 0.2 0.0053 15.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KEG13464.1 - 0.0058 15.4 0.0 0.0092 14.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KEG13464.1 - 0.006 15.7 1.5 0.084 11.9 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEG13464.1 - 0.0064 15.8 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KEG13464.1 - 0.0073 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEG13464.1 - 0.011 15.0 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEG13464.1 - 0.018 14.4 0.2 0.018 14.4 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_C PF05199.13 KEG13464.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase Trp_halogenase PF04820.14 KEG13464.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CLASP_N PF12348.8 KEG13465.1 - 9e-21 74.5 0.0 1.5e-18 67.2 0.0 3.0 2 1 1 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 KEG13465.1 - 0.011 16.1 16.3 0.69 10.3 0.0 6.9 6 2 2 9 9 9 0 HEAT repeats Cnd1 PF12717.7 KEG13465.1 - 0.28 11.2 2.2 4.7 7.2 0.0 3.6 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SNase PF00565.17 KEG13466.1 - 5.4e-41 139.4 0.0 1.4e-09 38.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KEG13466.1 - 4.3e-16 59.1 0.0 9.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain UQ_con PF00179.26 KEG13467.1 - 1.3e-37 128.5 0.0 1.8e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C2 PF00648.21 KEG13468.1 - 2.4e-07 30.1 0.0 1.1e-05 24.6 0.0 2.5 2 1 1 3 3 3 2 Calpain family cysteine protease STAR_dimer PF16544.5 KEG13468.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein DUF1295 PF06966.12 KEG13470.1 - 2.1e-29 102.7 9.3 3e-29 102.2 9.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Acyl-CoA_dh_1 PF00441.24 KEG13471.1 - 4.4e-06 27.0 0.1 5.7e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KEG13471.1 - 0.00092 19.5 0.0 0.0012 19.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spore_III_AE PF09546.10 KEG13471.1 - 0.0012 18.1 0.1 0.0014 17.9 0.1 1.0 1 0 0 1 1 1 1 Stage III sporulation protein AE (spore_III_AE) XRN_N PF03159.18 KEG13472.1 - 3.5e-22 79.0 0.0 5.1e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.17 KEG13472.1 - 0.12 12.9 0.0 0.77 10.3 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain ARD PF03079.14 KEG13474.1 - 2.2e-15 57.2 0.0 3.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.11 KEG13474.1 - 6.2e-13 48.4 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.11 KEG13474.1 - 2.7e-06 27.0 0.0 9.5e-06 25.2 0.0 1.9 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KEG13474.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KEG13474.1 - 0.011 15.4 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 KEG13474.1 - 0.038 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.22 KEG13474.1 - 0.098 12.3 0.0 0.62 9.7 0.0 2.0 1 1 1 2 2 2 0 Cupin TatD_DNase PF01026.21 KEG13480.1 - 1.8e-45 155.4 0.0 2.1e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase GCV_T PF01571.21 KEG13481.1 - 0.097 12.0 0.2 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain Fusion_gly PF00523.18 KEG13481.1 - 0.11 10.7 0.0 0.23 9.7 0.0 1.4 2 0 0 2 2 2 0 Fusion glycoprotein F0 Mit_KHE1 PF10173.9 KEG13485.1 - 0.031 14.3 0.1 0.032 14.3 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Katanin_con80 PF13925.6 KEG13487.1 - 0.065 13.3 4.1 0.26 11.3 4.1 2.1 1 0 0 1 1 1 0 con80 domain of Katanin Spc7 PF08317.11 KEG13487.1 - 1.1 8.0 30.5 0.17 10.8 13.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein PHP PF02811.19 KEG13487.1 - 1.6 9.0 4.7 7.7 6.8 4.7 2.2 1 1 0 1 1 1 0 PHP domain DUF720 PF05302.11 KEG13487.1 - 3.8 7.4 8.2 31 4.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF720) AAA PF00004.29 KEG13489.1 - 3.3e-87 289.6 0.0 4.8e-48 162.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG13489.1 - 1.5e-24 85.5 0.8 1.8e-11 43.7 0.4 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 KEG13489.1 - 2.4e-14 53.4 0.0 7.6e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEG13489.1 - 9e-14 52.2 0.4 4.9e-05 23.8 0.1 4.2 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KEG13489.1 - 6.9e-11 42.3 0.2 0.0003 20.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEG13489.1 - 3.4e-10 40.3 0.0 3.2e-05 24.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KEG13489.1 - 3.6e-09 36.9 0.0 0.0011 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEG13489.1 - 1.4e-08 35.1 0.7 0.015 15.6 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KEG13489.1 - 2.6e-07 30.8 0.0 0.033 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KEG13489.1 - 4.7e-07 30.2 0.0 0.033 14.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 KEG13489.1 - 1.5e-06 27.6 0.0 0.024 13.9 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.21 KEG13489.1 - 9.9e-06 25.1 0.1 0.047 13.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KEG13489.1 - 1.1e-05 25.5 0.3 0.11 12.4 0.0 3.6 5 0 0 5 5 3 2 NACHT domain AAA_18 PF13238.6 KEG13489.1 - 1.3e-05 25.8 0.0 0.066 13.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEG13489.1 - 1.3e-05 25.5 0.0 0.21 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KEG13489.1 - 1.5e-05 24.8 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 KEG13489.1 - 1.7e-05 25.4 0.0 0.36 11.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter TIP49 PF06068.13 KEG13489.1 - 1.8e-05 24.2 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 KEG13489.1 - 2.7e-05 24.2 0.2 0.063 13.2 0.0 2.6 2 1 1 3 3 3 2 Rad17 P-loop domain TsaE PF02367.17 KEG13489.1 - 2.8e-05 24.1 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KEG13489.1 - 3.9e-05 23.6 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEG13489.1 - 4.2e-05 23.4 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KEG13489.1 - 0.00014 21.7 0.0 0.47 10.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEG13489.1 - 0.00019 21.2 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 KEG13489.1 - 0.00022 21.1 0.1 0.01 15.8 0.0 2.7 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 KEG13489.1 - 0.00027 20.9 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEG13489.1 - 0.00038 19.7 0.0 0.73 9.0 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activat PF00158.26 KEG13489.1 - 0.00052 19.8 0.0 0.086 12.5 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KEG13489.1 - 0.0008 19.0 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 KEG13489.1 - 0.0015 19.0 0.3 0.33 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KEG13489.1 - 0.0015 17.7 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KEG13489.1 - 0.0022 18.3 0.1 2.4 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEG13489.1 - 0.0037 17.0 0.8 8.5 6.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.6 KEG13489.1 - 0.0037 17.4 0.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 KEG13489.1 - 0.0042 17.0 0.1 0.82 9.6 0.0 2.9 2 0 0 2 2 2 1 NTPase DUF815 PF05673.13 KEG13489.1 - 0.0063 15.7 0.0 3.4 6.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KEG13489.1 - 0.0071 16.2 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein MCM PF00493.23 KEG13489.1 - 0.0086 15.2 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_25 PF13481.6 KEG13489.1 - 0.0091 15.6 1.8 2.3 7.8 0.1 3.2 2 2 0 3 3 3 1 AAA domain ATPase PF06745.13 KEG13489.1 - 0.021 14.1 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 KaiC SKI PF01202.22 KEG13489.1 - 0.082 13.0 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.12 KEG13489.1 - 0.087 12.7 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 KEG13489.1 - 0.12 11.8 0.0 30 4.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein PduV-EutP PF10662.9 KEG13489.1 - 0.21 11.3 0.1 26 4.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ufd2P_core PF10408.9 KEG13491.1 - 6.1e-82 276.2 0.0 7.6e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.20 KEG13491.1 - 4.9e-21 74.7 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KEG13491.1 - 0.00023 20.2 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.6 KEG13491.1 - 0.0043 17.4 0.1 0.35 11.2 0.1 3.1 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KEG13491.1 - 0.011 16.2 0.3 0.39 11.2 0.3 2.7 1 1 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 KEG13491.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Baculo_LEF-2 PF03041.14 KEG13491.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 lef-2 U-box PF04564.15 KEG13491.1 - 0.081 13.1 0.4 0.36 11.0 0.4 2.1 1 1 0 1 1 1 0 U-box domain Thioredoxin_9 PF14595.6 KEG13491.1 - 0.095 12.5 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin Ribosomal_60s PF00428.19 KEG13491.1 - 0.19 12.3 8.1 0.15 12.6 1.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein NOA36 PF06524.12 KEG13491.1 - 1.1 8.5 3.2 2.2 7.5 3.2 1.4 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 KEG13492.1 - 3e-40 138.3 0.0 2.4e-39 135.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13492.1 - 4.9e-25 88.3 0.0 8.6e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG13492.1 - 0.00073 19.5 0.1 0.015 15.2 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 KEG13492.1 - 0.012 15.3 0.0 0.047 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 KEG13492.1 - 0.04 13.2 0.1 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Mo25 PF08569.11 KEG13493.1 - 7.1e-49 166.9 0.0 9.1e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Mo25-like APG5 PF04106.12 KEG13494.1 - 9.2e-06 25.4 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg5 DUF3070 PF11270.8 KEG13494.1 - 0.26 11.5 2.6 0.2 11.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) MAM33 PF02330.16 KEG13495.1 - 1.4e-30 106.8 1.9 5.7e-27 95.1 0.3 2.0 1 1 1 2 2 2 2 Mitochondrial glycoprotein WD40 PF00400.32 KEG13497.1 - 1.4e-16 60.6 13.0 0.0032 18.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KEG13497.1 - 9.6e-16 57.8 0.2 2e-15 56.8 0.2 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KEG13497.1 - 0.001 19.4 0.2 0.52 10.6 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain GCP_C_terminal PF04130.13 KEG13498.1 - 1.5e-20 73.9 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEG13498.1 - 6.6e-11 42.4 0.0 4.7e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal RT_RNaseH_2 PF17919.1 KEG13499.1 - 0.082 12.9 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase ACTH_domain PF00976.18 KEG13501.1 - 0.051 13.5 3.2 6.7 6.8 0.2 2.7 2 0 0 2 2 2 0 Corticotropin ACTH domain DUF4139 PF13598.6 KEG13503.1 - 3.2e-50 170.8 0.5 5.1e-50 170.1 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KEG13503.1 - 1.5e-09 38.1 0.8 1.5e-09 38.1 0.8 2.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Troponin PF00992.20 KEG13503.1 - 0.0017 18.6 1.2 0.0038 17.5 1.1 1.6 1 1 0 1 1 1 1 Troponin Rx_N PF18052.1 KEG13503.1 - 0.014 15.7 1.4 0.035 14.4 1.4 1.7 1 0 0 1 1 1 0 Rx N-terminal domain DUF2827 PF10933.8 KEG13503.1 - 0.15 10.7 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) NPV_P10 PF05531.12 KEG13503.1 - 0.16 12.5 1.3 0.43 11.1 1.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KEG13503.1 - 0.35 10.9 2.5 3.1 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nop25 PF09805.9 KEG13503.1 - 1 9.8 8.9 5.8 7.4 0.6 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Golgin_A5 PF09787.9 KEG13503.1 - 2.1 7.8 8.8 0.15 11.5 2.0 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 XhlA PF10779.9 KEG13503.1 - 7.9 6.8 9.5 0.22 11.7 2.7 2.0 2 0 0 2 2 2 0 Haemolysin XhlA HalX PF08663.10 KEG13503.1 - 9.4 6.6 9.6 3.8 7.9 2.5 2.4 2 0 0 2 2 2 0 HalX domain PPR_3 PF13812.6 KEG13504.1 - 0.034 14.2 0.2 2.5 8.3 0.0 3.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain AvrPtoB_bdg PF16847.5 KEG13504.1 - 0.13 12.8 0.0 0.67 10.5 0.0 2.1 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain HECT PF00632.25 KEG13505.1 - 1.6e-79 267.6 0.0 2.1e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Guanylate_cyc PF00211.20 KEG13507.1 - 5.3e-46 156.6 0.0 8.3e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fez1 PF06818.15 KEG13509.1 - 0.089 13.2 9.9 0.11 12.9 9.9 1.1 1 0 0 1 1 1 0 Fez1 FAM165 PF14981.6 KEG13509.1 - 0.12 12.1 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 FAM165 family Methyltr_RsmB-F PF01189.17 KEG13510.1 - 2e-68 230.0 0.0 3.4e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KEG13510.1 - 2.4e-08 34.4 0.0 1.6e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KEG13510.1 - 0.003 17.7 0.0 0.0075 16.4 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KEG13510.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1993 PF09351.10 KEG13510.1 - 0.12 12.6 0.4 0.34 11.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) MatB PF16449.5 KEG13510.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Fimbrillin MatB CorA PF01544.18 KEG13510.1 - 3.4 6.9 6.2 6.3 6.0 6.2 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein EPSP_synthase PF00275.20 KEG13513.1 - 0.016 13.9 0.2 0.036 12.8 0.0 1.6 2 0 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DAP_B PF07930.12 KEG13513.1 - 0.92 9.5 4.3 8.5 6.3 1.0 2.2 2 0 0 2 2 2 0 D-aminopeptidase, domain B V_ATPase_I PF01496.19 KEG13513.1 - 1.8 6.4 12.8 1.7 6.4 11.7 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family RNA_pol_Rpb2_6 PF00562.28 KEG13514.1 - 8.4e-124 413.6 0.0 1.1e-123 413.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEG13514.1 - 8.8e-43 146.2 0.0 1.2e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KEG13514.1 - 4.4e-31 107.1 0.2 1e-30 106.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KEG13514.1 - 1.1e-23 83.9 0.0 2.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KEG13514.1 - 1.7e-23 82.6 2.1 3.9e-23 81.5 2.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KEG13514.1 - 5.9e-23 80.8 0.1 1.8e-22 79.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KEG13514.1 - 2.6e-08 34.3 0.2 6.3e-08 33.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.11 KEG13514.1 - 0.058 13.3 2.5 0.074 13.0 0.9 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain C1_1 PF00130.22 KEG13514.1 - 0.17 11.8 1.4 0.36 10.7 1.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KEG13514.1 - 0.39 11.1 2.9 1.1 9.7 2.9 1.7 1 0 0 1 1 1 0 C1 domain RecR PF02132.15 KEG13514.1 - 2.4 7.8 5.0 4.5 6.9 4.3 1.8 2 0 0 2 2 2 0 RecR protein UCH PF00443.29 KEG13517.1 - 6e-41 140.6 0.0 1e-40 139.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG13517.1 - 3e-11 43.5 0.0 9.6e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KEG13517.1 - 1.5e-08 34.3 0.4 4.8e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family YukD PF08817.10 KEG13517.1 - 0.00019 22.1 0.2 0.00074 20.2 0.0 2.1 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 KEG13517.1 - 0.018 15.5 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF3450 PF11932.8 KEG13518.1 - 4.9e-05 22.8 12.0 4.9e-05 22.8 12.0 6.4 1 1 6 7 7 7 3 Protein of unknown function (DUF3450) SHE3 PF17078.5 KEG13518.1 - 0.0007 19.4 11.2 0.0007 19.4 11.2 4.0 2 1 0 3 3 3 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 KEG13518.1 - 0.0037 16.6 13.4 0.0037 16.6 13.4 4.6 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KEG13518.1 - 0.052 13.4 0.2 0.052 13.4 0.2 6.4 5 2 3 8 8 8 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3175 PF11373.8 KEG13519.1 - 0.0025 17.9 0.1 0.0039 17.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3175) Pkinase PF00069.25 KEG13520.1 - 1.1e-67 228.1 0.0 1.6e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13520.1 - 1.3e-30 106.6 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG13520.1 - 1.9e-06 27.4 0.0 0.00041 19.8 0.0 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 KEG13520.1 - 6.3e-06 26.3 0.0 0.042 13.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEG13520.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RHSP PF07999.11 KEG13523.1 - 6.7e-83 278.9 0.1 1.2e-82 278.1 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein Macro_2 PF14519.6 KEG13523.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain Kinesin PF00225.23 KEG13525.1 - 1.6e-77 260.7 4.3 3e-77 259.8 0.1 2.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG13525.1 - 6.9e-18 65.0 0.0 1.5e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KEG13525.1 - 0.055 13.9 0.3 0.055 13.9 0.3 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF4164 PF13747.6 KEG13525.1 - 4.9 7.5 8.3 0.42 10.9 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) MnmE_helical PF12631.7 KEG13525.1 - 5.8 7.0 9.6 1.6 8.9 4.5 2.4 1 1 1 2 2 2 0 MnmE helical domain RRM_1 PF00076.22 KEG13526.1 - 2.7e-14 52.8 0.0 4.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.19 KEG13527.1 - 4.5e-33 114.7 1.0 6.8e-33 114.1 1.0 1.2 1 0 0 1 1 1 1 MIF4G domain Band_7 PF01145.25 KEG13528.1 - 6.9e-23 81.6 3.6 9e-23 81.2 3.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KEG13528.1 - 6.1e-05 22.2 1.0 8.1e-05 21.8 1.0 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF4914 PF16260.5 KEG13528.1 - 0.054 11.6 0.5 0.07 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) DUF4200 PF13863.6 KEG13528.1 - 0.11 12.8 5.6 0.096 13.1 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WHAMM-JMY_N PF15920.5 KEG13528.1 - 0.2 11.5 0.8 0.36 10.7 0.8 1.3 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated WD40 PF00400.32 KEG13529.1 - 0.0011 19.7 3.1 0.064 14.2 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat SlyX PF04102.12 KEG13529.1 - 1.3 9.7 6.1 0.54 10.9 0.3 2.2 2 0 0 2 2 2 0 SlyX Nop PF01798.18 KEG13530.1 - 3.1e-13 49.7 0.3 3.1e-13 49.7 0.3 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KEG13530.1 - 0.0033 18.3 3.2 0.007 17.3 3.2 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Peptidase_S66 PF02016.15 KEG13530.1 - 0.18 11.9 0.5 2 8.5 0.0 2.2 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain TPR_12 PF13424.6 KEG13531.1 - 6.4e-07 29.6 16.7 0.032 14.5 0.5 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 KEG13531.1 - 1e-05 25.7 0.1 2.6e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 IQ PF00612.27 KEG13531.1 - 0.0086 15.8 16.2 0.17 11.7 3.0 4.6 4 0 0 4 4 4 2 IQ calmodulin-binding motif TPR_8 PF13181.6 KEG13531.1 - 0.061 13.6 7.6 15 6.1 0.3 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13531.1 - 0.25 11.5 13.8 4.2 7.7 0.4 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TetR_C_7 PF14246.6 KEG13531.1 - 1.7 8.7 6.1 0.24 11.4 0.1 2.8 3 0 0 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain TPR_16 PF13432.6 KEG13531.1 - 1.8 9.3 15.3 2 9.1 0.6 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13531.1 - 4.8 8.3 18.2 71 4.6 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat CLU PF13236.6 KEG13532.1 - 2.3e-11 44.0 0.0 1.7e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KEG13532.1 - 0.0026 17.8 0.6 0.005 16.9 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 KEG13532.1 - 0.0035 17.3 3.6 0.12 12.6 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13532.1 - 0.0066 16.7 0.9 0.036 14.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat CLU PF13236.6 KEG13533.1 - 2.6e-11 43.8 0.0 1.5e-10 41.3 0.0 2.4 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KEG13533.1 - 0.0017 18.4 0.0 0.0057 16.7 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 KEG13533.1 - 0.25 11.5 2.3 75 3.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.22 KEG13534.1 - 7e-46 155.8 0.0 8.2e-46 155.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG13534.1 - 1.3e-34 119.0 0.0 2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG13534.1 - 3.7e-17 62.3 0.0 4.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG13534.1 - 9.5e-06 25.1 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG13534.1 - 3.3e-05 23.9 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG13534.1 - 6.9e-05 22.5 0.0 0.00013 21.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEG13534.1 - 0.007 16.3 0.4 0.035 14.0 0.2 2.1 2 1 1 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 KEG13534.1 - 0.0094 15.7 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEG13534.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KEG13534.1 - 0.023 15.1 1.0 0.072 13.5 1.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEG13534.1 - 0.027 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KEG13534.1 - 0.028 14.2 0.1 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MCM PF00493.23 KEG13534.1 - 0.046 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 KEG13534.1 - 0.052 13.1 0.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEG13534.1 - 0.06 13.9 0.1 0.079 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KEG13534.1 - 0.071 12.3 0.4 3.7 6.6 0.1 2.3 2 1 1 3 3 3 0 G-protein alpha subunit DUF815 PF05673.13 KEG13534.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KEG13534.1 - 0.13 12.8 0.0 0.13 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEG13534.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_14 PF13428.6 KEG13540.1 - 5e-11 42.5 16.5 0.099 13.5 0.2 7.7 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13540.1 - 0.0092 16.0 0.6 0.57 10.4 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PRP1_N PF06424.12 KEG13540.1 - 0.017 15.5 0.2 0.048 14.1 0.2 1.8 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal TPR_20 PF14561.6 KEG13540.1 - 0.062 13.6 0.9 0.46 10.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13540.1 - 0.086 13.1 0.8 3.2 8.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KEG13540.1 - 0.086 12.0 8.0 0.11 11.6 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13540.1 - 0.097 13.0 5.4 0.88 9.9 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG13540.1 - 0.16 12.5 9.2 13 6.4 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG13540.1 - 0.2 11.6 0.9 3.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 KEG13541.1 - 0.00028 20.6 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PAP_assoc PF03828.19 KEG13543.1 - 5e-13 49.1 0.0 9.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEG13543.1 - 0.0072 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain NUDIX PF00293.28 KEG13544.1 - 0.00014 21.9 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Methyltr_RsmB-F PF01189.17 KEG13545.1 - 8.2e-27 94.1 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F IQ PF00612.27 KEG13547.1 - 0.0027 17.4 2.6 0.008 15.9 2.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_12 PF13424.6 KEG13547.1 - 0.0028 17.9 0.7 0.0028 17.9 0.7 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13547.1 - 0.013 15.6 5.3 0.35 11.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13547.1 - 0.019 14.8 0.4 5 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 KEG13548.1 - 3.7e-59 200.7 0.0 5.2e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_3_Rpc31 PF11705.8 KEG13548.1 - 4 7.6 14.6 7.3 6.8 14.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HAD_2 PF13419.6 KEG13549.1 - 1.8e-05 24.9 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEG13549.1 - 0.00041 20.7 0.0 0.00057 20.2 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEG13549.1 - 0.0036 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like 4HBT_3 PF13622.6 KEG13550.1 - 0.021 15.1 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily MIP PF00230.20 KEG13551.1 - 7.9e-35 120.6 14.9 1e-34 120.2 14.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein MtrB PF05440.12 KEG13551.1 - 0.77 10.2 4.4 9.3 6.7 0.8 2.6 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B ABC_tran PF00005.27 KEG13553.1 - 4.3e-50 169.8 0.0 5.8e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEG13553.1 - 6.1e-42 144.1 24.8 1.2e-24 87.5 2.8 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 KEG13553.1 - 2e-08 34.3 0.0 0.0091 16.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KEG13553.1 - 5.4e-08 32.5 0.2 0.07 12.6 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG13553.1 - 2.5e-07 30.3 0.9 0.016 14.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEG13553.1 - 6e-07 29.5 0.1 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KEG13553.1 - 2e-06 27.9 0.2 0.95 9.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEG13553.1 - 3.9e-06 27.5 0.1 0.073 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEG13553.1 - 1.1e-05 25.2 0.4 0.0019 18.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KEG13553.1 - 7.1e-05 22.9 1.2 0.018 15.1 0.3 2.6 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KEG13553.1 - 0.00029 21.2 0.0 0.2 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEG13553.1 - 0.00061 19.2 0.1 0.24 10.7 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KEG13553.1 - 0.00072 19.8 0.0 0.37 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KEG13553.1 - 0.002 18.2 2.3 0.072 13.2 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KEG13553.1 - 0.0023 17.7 0.3 0.83 9.4 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 KEG13553.1 - 0.0055 17.3 0.1 0.4 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KEG13553.1 - 0.0066 16.0 0.7 2.9 7.4 0.2 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KEG13553.1 - 0.0067 16.6 0.0 0.098 12.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KEG13553.1 - 0.012 15.5 0.4 0.17 11.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 KEG13553.1 - 0.015 14.4 0.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 KEG13553.1 - 0.016 14.7 0.0 0.8 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEG13553.1 - 0.019 15.3 0.0 7.9 6.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 KEG13553.1 - 0.025 14.3 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG13553.1 - 0.028 14.4 0.2 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 KEG13553.1 - 0.03 13.3 0.1 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KEG13553.1 - 0.034 13.4 0.1 4.1 6.6 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin IIGP PF05049.13 KEG13553.1 - 0.04 13.0 0.7 3.9 6.4 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KEG13553.1 - 0.058 13.6 0.0 9.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KEG13553.1 - 0.06 13.0 0.1 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 KEG13553.1 - 0.069 12.4 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Septin cobW PF02492.19 KEG13553.1 - 0.12 11.9 0.7 1 8.9 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KEG13553.1 - 0.14 12.4 0.3 9.6 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KEG13553.1 - 0.14 12.1 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_27 PF13514.6 KEG13553.1 - 0.18 11.4 0.1 22 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain CcmD PF04995.14 KEG13553.1 - 4.7 7.4 12.7 0.13 12.4 0.4 4.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) SIR2 PF02146.17 KEG13554.1 - 4.6e-50 170.0 0.0 5.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SIS PF01380.22 KEG13554.1 - 0.00039 20.3 0.0 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 SIS domain TraU PF06834.11 KEG13554.1 - 0.019 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 TraU protein TPP_enzyme_M PF00205.22 KEG13554.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DoxX PF07681.12 KEG13555.1 - 4.3e-05 24.0 8.9 5.3e-05 23.7 8.0 1.6 2 0 0 2 2 2 1 DoxX HR_lesion PF05514.11 KEG13555.1 - 0.025 14.7 4.8 0.044 14.0 4.8 1.4 1 1 0 1 1 1 0 HR-like lesion-inducing ubiquitin PF00240.23 KEG13556.1 - 2.2e-22 78.6 0.1 2.4e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KEG13556.1 - 7.6e-11 41.7 0.1 8.5e-11 41.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEG13556.1 - 0.00011 22.5 0.1 0.00036 20.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEG13556.1 - 0.00029 20.9 0.1 0.0014 18.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KEG13556.1 - 0.012 16.2 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KEG13556.1 - 0.019 15.0 0.3 1.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KEG13556.1 - 0.064 13.6 0.2 0.076 13.4 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KEG13556.1 - 0.17 11.8 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain PLDc_2 PF13091.6 KEG13558.1 - 1.9e-30 105.5 0.0 7e-22 77.8 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KEG13558.1 - 4.8e-10 39.2 3.7 0.00012 22.1 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif RNHCP PF12647.7 KEG13559.1 - 0.32 11.0 3.0 6.9 6.7 0.0 2.6 3 0 0 3 3 3 0 RNHCP domain PAM2 PF07145.15 KEG13562.1 - 0.062 13.0 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Pkinase PF00069.25 KEG13563.1 - 4.2e-58 196.8 0.0 5.6e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13563.1 - 1.7e-29 102.9 0.0 4.4e-29 101.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Abi_2 PF07751.11 KEG13563.1 - 0.001 19.4 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Abi-like protein Kinase-like PF14531.6 KEG13563.1 - 0.0036 16.7 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEG13563.1 - 0.035 14.0 0.1 1 9.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG13563.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DivIC PF04977.15 KEG13564.1 - 0.26 11.1 5.9 0.38 10.6 3.6 2.5 2 0 0 2 2 2 0 Septum formation initiator Snapin_Pallidin PF14712.6 KEG13564.1 - 1.1 9.7 6.9 2 8.9 1.7 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 KEG13564.1 - 1.2 9.2 6.7 0.81 9.7 1.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KEG13564.1 - 2.2 8.7 28.4 0.02 15.3 14.9 3.2 2 1 1 3 3 3 0 Fez1 HIP1_clath_bdg PF16515.5 KEG13564.1 - 3.2 8.4 16.9 0.23 12.1 4.6 3.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SUIM_assoc PF16619.5 KEG13565.1 - 1.2 9.3 17.8 0.8 9.8 2.6 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pex14_N PF04695.13 KEG13565.1 - 2.3 8.9 10.6 5.4 7.6 4.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.11 KEG13565.1 - 2.7 8.0 10.4 8.9 6.3 4.2 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Dscam_C PF12355.8 KEG13565.1 - 3.2 8.8 6.0 24 5.9 0.4 2.8 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal DUF1935 PF09149.10 KEG13568.1 - 0.051 14.0 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) ENT PF03735.14 KEG13568.1 - 0.074 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 ENT domain DUF2613 PF11021.8 KEG13568.1 - 0.25 11.5 4.6 0.14 12.3 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Pkinase PF00069.25 KEG13570.1 - 8.3e-20 71.3 0.0 8.5e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13570.1 - 5.5e-14 52.1 0.0 5.8e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG13570.1 - 0.019 13.8 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KEG13570.1 - 0.038 13.3 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KEG13570.1 - 0.04 13.5 0.0 0.049 13.2 0.0 1.0 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KEG13570.1 - 0.078 12.9 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 KEG13571.1 - 0.0063 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KEG13571.1 - 0.17 12.3 0.5 1.8 9.0 0.1 2.6 2 1 0 2 2 2 0 HEAT repeats Pkr1 PF08636.10 KEG13572.1 - 2.1e-11 43.8 6.0 2.6e-11 43.5 6.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4175 PF13779.6 KEG13572.1 - 0.0037 15.3 0.1 0.0044 15.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) PPR_2 PF13041.6 KEG13573.1 - 8.4e-20 70.7 2.3 1.3e-05 25.3 0.0 5.9 6 0 0 6 6 6 3 PPR repeat family PPR_long PF17177.4 KEG13573.1 - 3.6e-17 62.5 0.2 3.9e-06 26.4 0.0 3.4 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KEG13573.1 - 6.3e-16 58.2 0.6 4.8e-07 29.8 0.1 4.7 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 KEG13573.1 - 1.5e-09 37.5 8.5 0.012 15.8 0.3 6.4 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 KEG13573.1 - 5.5e-06 26.0 1.0 0.68 9.7 0.0 4.5 4 1 0 4 4 4 2 PPR repeat RPN7 PF10602.9 KEG13573.1 - 0.0025 17.5 4.2 0.08 12.6 0.1 3.3 3 0 0 3 3 3 1 26S proteasome subunit RPN7 IF-2 PF11987.8 KEG13573.1 - 0.019 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Translation-initiation factor 2 TPR_14 PF13428.6 KEG13573.1 - 0.57 11.2 4.0 6.6 7.8 0.1 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat F_actin_cap_B PF01115.17 KEG13574.1 - 5.2e-44 150.7 0.0 6.7e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Peptidase_M20 PF01546.28 KEG13575.1 - 1.1e-30 106.9 0.6 1.4e-30 106.5 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEG13575.1 - 3.7e-09 36.5 0.0 1.3e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEG13575.1 - 0.034 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Radical_SAM_C PF16199.5 KEG13575.1 - 0.18 11.9 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Thi4 PF01946.17 KEG13575.1 - 0.23 10.6 2.8 2.2 7.5 0.0 2.7 2 1 1 3 3 3 0 Thi4 family Peptidase_M20 PF01546.28 KEG13576.1 - 1e-20 74.4 0.0 1.2e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KEG13576.1 - 0.0072 16.0 0.0 0.0074 16.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Radical_SAM_C PF16199.5 KEG13578.1 - 0.055 13.5 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Radical_SAM C-terminal domain M20_dimer PF07687.14 KEG13579.1 - 1.1e-09 38.1 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KEG13579.1 - 4.6e-08 33.0 0.0 4.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 OST-HTH PF12872.7 KEG13580.1 - 0.0034 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain RNA_ligase PF09414.10 KEG13581.1 - 6.2e-20 72.1 0.0 9.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 KEG13581.1 - 8.4e-09 35.4 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal FLILHELTA PF10306.9 KEG13581.1 - 0.12 12.8 0.0 0.97 9.9 0.0 2.2 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA tRNA_U5-meth_tr PF05958.11 KEG13583.1 - 3.3e-17 62.5 0.0 2.8e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KEG13583.1 - 5.4e-11 42.5 0.0 1.2e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG13583.1 - 3.2e-09 37.4 0.0 8.2e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEG13583.1 - 1.8e-06 27.6 0.8 2.7e-06 27.0 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KEG13583.1 - 3.5e-06 26.8 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KEG13583.1 - 9.2e-06 26.2 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KEG13583.1 - 0.00018 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KEG13583.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KEG13583.1 - 0.0021 17.5 0.4 0.0021 17.5 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KEG13583.1 - 0.0029 17.1 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KEG13583.1 - 0.0034 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEG13583.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KEG13583.1 - 0.067 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KEG13583.1 - 0.08 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEG13583.1 - 0.11 13.2 0.0 0.24 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 KEG13583.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RIC3 PF15361.6 KEG13584.1 - 3.3 8.1 6.7 8.4 6.8 6.7 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SNAP PF14938.6 KEG13585.1 - 1.4e-58 198.5 19.0 1.8e-58 198.2 19.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 KEG13585.1 - 2.3e-06 27.2 4.5 2.8e-06 26.9 4.5 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 KEG13585.1 - 2.2e-05 24.1 10.9 0.049 13.7 0.0 6.4 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13585.1 - 0.00012 22.6 19.8 0.77 10.5 1.9 5.4 4 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13585.1 - 0.0017 18.6 1.5 0.0017 18.6 1.5 4.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG13585.1 - 0.002 18.6 19.2 4.4 8.2 0.3 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13585.1 - 0.0044 17.1 15.8 5.2 7.5 0.2 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13585.1 - 0.0075 16.1 16.1 0.4 10.6 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG13585.1 - 0.013 16.0 14.7 0.082 13.4 0.4 4.1 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13585.1 - 0.013 15.5 24.5 2.9 8.2 0.2 7.1 7 1 2 9 9 9 0 Tetratricopeptide repeat DUF627 PF04781.12 KEG13585.1 - 0.034 14.2 2.8 0.23 11.5 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF627) TRAPPC-Trs85 PF12739.7 KEG13585.1 - 0.039 12.9 3.9 0.057 12.4 3.7 1.4 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PPR PF01535.20 KEG13585.1 - 0.067 13.5 4.2 6 7.3 0.1 4.3 4 0 0 4 4 4 0 PPR repeat TPR_14 PF13428.6 KEG13585.1 - 0.073 13.9 14.4 13 6.9 0.0 5.8 4 2 2 6 6 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KEG13585.1 - 0.084 12.4 6.7 0.24 11.0 0.2 2.9 2 1 1 3 3 3 0 Foie gras liver health family 1 TPR_11 PF13414.6 KEG13585.1 - 0.17 11.6 0.1 0.17 11.6 0.1 4.8 5 0 0 5 5 5 0 TPR repeat RPN7 PF10602.9 KEG13585.1 - 0.38 10.4 8.7 0.4 10.4 4.7 2.8 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KEG13585.1 - 0.46 10.4 11.3 29 4.7 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 KEG13586.1 - 4.4e-43 147.9 0.0 1.1e-42 146.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KEG13586.1 - 0.00082 18.9 0.0 0.0033 16.9 0.0 1.9 2 0 0 2 2 2 1 CHAT domain PIP5K PF01504.18 KEG13588.1 - 2.7e-33 115.4 0.3 3.8e-26 91.9 0.6 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 KEG13588.1 - 9.7e-15 54.5 6.7 2.8e-14 53.0 6.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 KEG13588.1 - 3.1e-14 52.5 0.0 4.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IBR PF01485.21 KEG13588.1 - 0.76 10.0 4.6 0.88 9.8 2.3 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain E1_dh PF00676.20 KEG13589.1 - 1.4e-60 204.8 0.0 2.2e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KEG13589.1 - 1e-51 175.2 0.0 1.7e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KEG13589.1 - 5.9e-37 126.7 0.0 1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KEG13589.1 - 1.4e-05 24.6 0.0 3.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Sep15_SelM PF08806.11 KEG13590.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain DUF1126 PF06565.12 KEG13591.1 - 7.8e-79 260.3 1.5 9.7e-26 89.7 0.1 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_8 PF13833.6 KEG13591.1 - 2.5e-05 24.0 0.2 0.00077 19.3 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KEG13591.1 - 2.7e-05 24.5 0.1 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair TTRAP PF14203.6 KEG13591.1 - 0.036 14.1 1.5 0.29 11.1 0.5 2.6 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein WD40 PF00400.32 KEG13592.1 - 2.1e-05 25.2 14.8 0.4 11.6 0.3 7.3 9 0 0 9 9 9 3 WD domain, G-beta repeat NUMOD4 PF07463.11 KEG13592.1 - 0.14 12.4 0.2 0.34 11.1 0.2 1.7 1 0 0 1 1 1 0 NUMOD4 motif p6 PF17548.2 KEG13593.1 - 0.14 12.2 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Histone-like Protein p6 SOCS_box PF07525.16 KEG13594.1 - 1.2 9.6 3.7 51 4.3 0.0 4.1 4 0 0 4 4 4 0 SOCS box His_Phos_1 PF00300.22 KEG13595.1 - 0.12 12.0 1.1 0.21 11.3 1.1 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Beta_helix PF13229.6 KEG13596.1 - 2e-83 278.0 104.8 4.7e-16 59.0 8.3 15.9 12 4 3 17 17 17 12 Right handed beta helix region NosD PF05048.13 KEG13596.1 - 3.6e-57 193.4 57.4 1.5e-11 44.0 0.9 14.3 9 5 2 13 13 13 10 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KEG13596.1 - 0.015 14.6 73.3 0.37 10.1 0.0 10.7 8 2 2 11 11 11 0 Protein of unknown function (DUF1565) Pectate_lyase_3 PF12708.7 KEG13596.1 - 0.78 9.5 33.2 0.084 12.7 0.6 6.2 5 1 0 6 6 6 0 Pectate lyase superfamily protein Glutaredoxin PF00462.24 KEG13597.1 - 6.1e-16 58.4 0.0 7.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KEG13597.1 - 1.5e-05 25.0 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 KEG13597.1 - 0.0002 21.7 0.0 0.00024 21.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 KEG13597.1 - 0.00072 19.8 0.1 1.2 9.2 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KEG13597.1 - 0.0009 19.7 0.0 0.00099 19.5 0.0 1.2 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 KEG13597.1 - 0.014 15.2 0.1 2.2 8.0 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 KEG13597.1 - 0.023 15.1 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zf-RING_7 PF02591.15 KEG13597.1 - 0.027 14.7 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain GST_N_2 PF13409.6 KEG13597.1 - 0.04 14.2 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AhpC-TSA PF00578.21 KEG13597.1 - 0.046 13.6 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KEG13597.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Redoxin SET PF00856.28 KEG13598.1 - 3.5e-10 40.5 0.2 1.1e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 SET domain F-box-like PF12937.7 KEG13599.1 - 0.0005 19.9 2.3 0.0024 17.7 2.3 2.2 1 0 0 1 1 1 1 F-box-like DUF2975 PF11188.8 KEG13599.1 - 2.9 7.8 16.9 0.044 13.7 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) CBF PF03914.17 KEG13600.1 - 0.015 15.3 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 CBF/Mak21 family Baculo_LEF5_C PF11792.8 KEG13602.1 - 0.19 11.5 0.0 0.57 9.9 0.0 1.8 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Flagellar_rod PF05149.12 KEG13605.1 - 2.2e-92 309.6 18.6 2.2e-92 309.6 18.6 2.1 3 0 0 3 3 3 1 Paraflagellar rod protein Baculo_PEP_C PF04513.12 KEG13605.1 - 0.0019 18.2 4.3 12 5.9 0.0 4.4 3 2 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3417 PF11897.8 KEG13605.1 - 0.26 11.7 2.9 3.2 8.2 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) TPR_1 PF00515.28 KEG13605.1 - 0.53 10.2 2.2 0.62 10.0 0.6 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Erp_C PF06780.11 KEG13605.1 - 0.69 9.9 4.7 0.54 10.3 0.9 2.6 2 0 0 2 2 2 0 Erp protein C-terminus Peptidase_C97 PF05903.14 KEG13608.1 - 1.4e-24 86.7 0.1 6.2e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 PPPDE putative peptidase domain Kelch_4 PF13418.6 KEG13609.1 - 8.9e-26 89.7 0.0 9.5e-06 25.5 0.0 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG13609.1 - 7.9e-19 67.2 1.7 0.0026 17.7 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 KEG13609.1 - 1.3e-17 63.7 2.4 0.00029 21.0 0.0 6.9 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG13609.1 - 9e-16 57.2 10.2 2e-06 27.2 0.1 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KEG13609.1 - 2.9e-12 46.4 1.0 0.0051 17.1 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KEG13609.1 - 1.6e-09 37.3 12.5 0.0071 16.3 0.0 6.3 6 1 0 6 6 6 3 Kelch motif DZR PF12773.7 KEG13610.1 - 0.00065 19.7 2.4 0.041 13.9 0.1 2.4 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_10 PF10058.9 KEG13610.1 - 0.035 13.8 6.3 7.5 6.4 0.1 3.7 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Lycopene_cycl PF05834.12 KEG13610.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RNHCP PF12647.7 KEG13610.1 - 0.13 12.2 1.7 6.6 6.8 0.0 3.2 3 0 0 3 3 3 0 RNHCP domain HalOD2 PF18547.1 KEG13610.1 - 0.25 11.3 6.7 4.6 7.2 0.2 3.9 4 0 0 4 4 4 0 Halobacterial output domain 2 Zn-ribbon_8 PF09723.10 KEG13610.1 - 3 8.0 7.5 2.8 8.1 0.5 3.2 2 2 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KEG13610.1 - 9.5 6.3 9.7 54 3.9 0.1 4.0 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Mito_carr PF00153.27 KEG13611.1 - 4.7e-46 154.7 1.9 1.1e-15 57.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C97 PF05903.14 KEG13613.1 - 1.9e-22 79.7 0.0 3.1e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain TetR_C_30 PF17939.1 KEG13613.1 - 0.0038 17.5 0.0 0.0075 16.5 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Armet PF10208.9 KEG13613.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding DIMCO_N PF16844.5 KEG13613.1 - 0.029 14.7 0.2 0.082 13.2 0.0 1.7 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Peptidase_C97 PF05903.14 KEG13615.1 - 2.1e-13 50.4 0.0 3.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA PF00004.29 KEG13617.1 - 6.9e-36 123.6 0.0 1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG13617.1 - 2.1e-06 27.4 0.0 8.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 KEG13617.1 - 3.2e-06 27.0 0.0 7.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KEG13617.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG13617.1 - 2.1e-05 24.8 0.3 0.0037 17.5 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEG13617.1 - 0.00049 19.9 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KEG13617.1 - 0.00096 18.4 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KEG13617.1 - 0.0032 17.2 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KEG13617.1 - 0.0035 17.7 0.1 0.01 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEG13617.1 - 0.011 15.7 0.1 0.03 14.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEG13617.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KEG13617.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain LisH PF08513.11 KEG13617.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 LisH AAA_33 PF13671.6 KEG13617.1 - 0.032 14.4 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEG13617.1 - 0.033 14.6 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KEG13617.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEG13617.1 - 0.038 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 KEG13617.1 - 0.051 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KEG13617.1 - 0.069 12.7 0.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KEG13617.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KEG13617.1 - 0.12 11.7 0.1 1.5 8.2 0.1 2.1 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.6 KEG13617.1 - 0.17 12.1 0.1 0.37 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain LisH_TPL PF17814.1 KEG13617.1 - 0.2 11.3 0.2 0.6 9.8 0.2 1.9 1 0 0 1 1 1 0 LisH-like dimerisation domain Actin PF00022.19 KEG13618.1 - 3.7e-125 417.7 0.0 1e-124 416.3 0.0 1.6 1 1 0 1 1 1 1 Actin TRM PF02005.16 KEG13619.1 - 3.1e-101 339.3 1.0 3.8e-74 250.1 0.3 2.9 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Glyco_transf_25 PF01755.17 KEG13620.1 - 8.7e-17 61.6 0.0 6e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Myb_DNA-bind_6 PF13921.6 KEG13621.1 - 0.0015 18.7 0.2 0.056 13.7 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Atg14 PF10186.9 KEG13621.1 - 6.8 5.7 10.1 1.3 8.0 1.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_6 PF13516.6 KEG13622.1 - 8.8e-08 31.6 0.2 0.0039 17.1 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KEG13622.1 - 0.00077 19.2 0.2 0.063 13.0 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KEG13622.1 - 0.0035 17.7 0.1 0.011 16.1 0.1 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG13622.1 - 0.03 14.8 1.5 7.6 7.5 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat Pdase_M17_N2 PF18295.1 KEG13623.1 - 0.049 13.9 0.1 0.17 12.2 0.1 1.9 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Patatin PF01734.22 KEG13624.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase FANC_SAP PF18081.1 KEG13624.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain Swi3 PF07962.12 KEG13625.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 SUIM_assoc PF16619.5 KEG13625.1 - 9.3 6.4 19.4 0.065 13.3 1.3 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Kelch_4 PF13418.6 KEG13626.1 - 1.8e-19 69.5 4.2 0.00033 20.6 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KEG13626.1 - 1.8e-12 47.2 16.5 0.0004 20.6 0.1 7.5 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG13626.1 - 5.3e-12 45.4 13.3 0.013 15.4 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KEG13626.1 - 4.1e-11 42.7 4.8 0.0044 17.3 0.1 6.4 7 0 0 7 7 7 3 Kelch motif BTB_2 PF02214.22 KEG13626.1 - 6.5e-09 36.0 0.6 1.7e-06 28.3 0.2 2.6 2 0 0 2 2 2 2 BTB/POZ domain Kelch_1 PF01344.25 KEG13626.1 - 4e-08 32.7 17.7 0.031 13.8 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KEG13626.1 - 7.1e-08 32.1 5.6 0.27 11.3 0.1 6.2 6 0 0 6 6 6 2 Kelch motif Peptidase_M16_C PF05193.21 KEG13628.1 - 6.2e-07 29.6 0.0 2e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEG13628.1 - 1.4e-05 25.1 0.1 0.00015 21.8 0.1 2.2 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) PDZ_2 PF13180.6 KEG13631.1 - 0.0002 21.6 0.0 0.00055 20.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEG13631.1 - 0.00037 20.8 0.0 0.0053 17.1 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KEG13631.1 - 0.00064 19.5 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PIF1 PF05970.14 KEG13632.1 - 3.5e-36 125.1 0.8 9.9e-29 100.6 0.4 3.5 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KEG13632.1 - 2.9e-22 79.3 0.0 5.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG13632.1 - 1.7e-07 31.6 0.1 6.9e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG13632.1 - 5.5e-05 23.4 0.6 0.2 11.9 0.1 3.0 3 0 0 3 3 3 2 AAA domain Herpes_Helicase PF02689.14 KEG13632.1 - 0.0016 16.5 0.2 0.77 7.6 0.0 3.2 3 1 1 4 4 4 2 Helicase AAA_5 PF07728.14 KEG13632.1 - 0.0039 17.2 0.1 0.031 14.3 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 KEG13632.1 - 0.011 15.6 0.5 0.086 12.7 0.5 2.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KEG13632.1 - 0.019 15.3 0.2 0.05 14.0 0.2 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KEG13632.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KEG13632.1 - 0.071 13.6 0.2 0.24 11.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DEAD PF00270.29 KEG13632.1 - 0.1 12.4 0.6 3.3 7.5 0.1 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 KEG13632.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KEG13632.1 - 0.15 11.8 0.1 0.64 9.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEG13632.1 - 0.4 10.4 3.5 0.41 10.4 0.0 2.8 3 1 1 4 4 4 0 AAA domain PIF1 PF05970.14 KEG13633.1 - 4.3e-36 124.9 2.5 4e-29 101.9 0.3 3.3 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KEG13633.1 - 2.2e-21 76.5 0.0 4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG13633.1 - 2.1e-06 28.1 0.7 9e-06 26.1 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG13633.1 - 0.00062 20.1 2.5 0.0062 16.8 0.9 3.3 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KEG13633.1 - 0.0011 18.7 0.6 0.91 9.2 0.0 3.3 2 2 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 KEG13633.1 - 0.003 15.6 0.7 0.88 7.4 0.0 2.8 2 1 1 3 3 3 2 Helicase UvrD_C_2 PF13538.6 KEG13633.1 - 0.015 15.1 0.4 0.098 12.5 0.4 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KEG13633.1 - 0.019 14.7 0.2 0.048 13.4 0.2 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KEG13633.1 - 0.04 13.7 2.1 2.5 7.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.14 KEG13633.1 - 0.073 13.1 0.3 0.31 11.1 0.2 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3074 PF11274.8 KEG13634.1 - 0.0044 17.0 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Antimicrobial_6 PF08036.11 KEG13635.1 - 0.086 12.9 0.3 23 5.2 0.1 2.5 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide UPF0242 PF06785.11 KEG13635.1 - 0.23 11.6 11.4 0.21 11.7 7.6 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 KEG13635.1 - 4.3 7.7 8.4 3.8 7.8 3.7 3.2 1 1 1 2 2 2 0 Uncharacterized conserved protein Sec20 PF03908.13 KEG13636.1 - 3.1e-07 30.2 1.4 3.1e-07 30.2 1.4 1.7 2 1 0 2 2 2 1 Sec20 SlyX PF04102.12 KEG13637.1 - 0.05 14.2 0.8 19 5.9 0.1 2.9 3 0 0 3 3 3 0 SlyX DUF1499 PF07386.11 KEG13637.1 - 0.12 12.9 1.3 4.6 7.8 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1499) WD40 PF00400.32 KEG13639.1 - 7.8e-16 58.2 15.0 0.00033 21.4 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13639.1 - 0.00012 22.3 0.1 0.35 11.2 0.0 4.2 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEG13639.1 - 0.00071 18.4 1.5 0.39 9.3 0.3 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEG13639.1 - 0.038 12.7 0.1 0.23 10.2 0.1 2.2 1 1 0 1 1 1 0 Nup133 N terminal like CENP-H PF05837.12 KEG13639.1 - 0.13 12.7 33.4 0.95 9.9 11.6 3.7 2 1 2 4 4 4 0 Centromere protein H (CENP-H) DUF4193 PF13834.6 KEG13639.1 - 0.25 11.9 4.4 0.9 10.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) KASH_CCD PF14662.6 KEG13639.1 - 0.37 10.6 25.2 0.71 9.7 25.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 KEG13639.1 - 0.4 10.6 24.5 0.78 9.6 0.8 4.0 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor PI3K_P85_iSH2 PF16454.5 KEG13639.1 - 0.52 9.9 23.3 19 4.8 23.3 2.3 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_TATA_bd PF12325.8 KEG13639.1 - 0.91 9.8 29.6 2.1 8.6 19.5 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FAD_binding_6 PF00970.24 KEG13640.1 - 2.6e-08 34.1 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEG13640.1 - 0.00017 22.2 0.0 0.0005 20.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Comm PF15957.5 KEG13640.1 - 0.0089 16.4 0.0 0.02 15.2 0.0 1.6 1 1 0 1 1 1 1 Commissureless PEPCK_ATP PF01293.20 KEG13641.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Pkinase PF00069.25 KEG13642.1 - 2.5e-52 177.8 0.0 4.4e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13642.1 - 2.6e-28 99.0 0.0 4.3e-26 91.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG13642.1 - 4.7e-05 22.3 1.6 0.00015 20.7 1.6 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG13642.1 - 0.0016 17.8 0.1 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.9 KEG13642.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KEG13642.1 - 0.063 13.2 0.1 0.35 10.8 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KEG13642.1 - 0.18 11.3 0.7 0.52 9.9 0.7 1.7 1 1 0 1 1 1 0 RIO1 family DUF5555 PF17710.1 KEG13642.1 - 0.63 9.5 8.3 0.29 10.6 1.3 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5555) SeqA PF03925.13 KEG13645.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 SeqA protein C-terminal domain NAD_binding_2 PF03446.15 KEG13646.1 - 2.8e-30 105.6 0.0 2.8e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEG13646.1 - 1.1e-13 51.5 1.0 1.8e-12 47.5 1.0 2.4 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KEG13646.1 - 0.0037 17.3 0.1 0.0076 16.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KEG13646.1 - 0.14 13.0 0.0 0.85 10.5 0.0 2.2 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SecE PF00584.20 KEG13647.1 - 4.8e-12 45.6 0.1 5.7e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex 2OG-FeII_Oxy PF03171.20 KEG13648.1 - 1.9e-16 60.4 0.0 4.1e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KEG13648.1 - 0.0084 16.9 0.0 1 10.2 0.0 2.6 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy_3 PF13640.6 KEG13648.1 - 0.011 16.7 0.0 0.02 15.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tropomyosin_1 PF12718.7 KEG13649.1 - 1.7 8.8 4.8 0.6 10.3 0.6 2.1 2 0 0 2 2 2 0 Tropomyosin like Complex1_LYR PF05347.15 KEG13650.1 - 3.2e-06 27.1 0.0 7.3e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DHC_N1 PF08385.12 KEG13651.1 - 5e-152 507.4 3.9 5e-152 507.4 3.9 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KEG13651.1 - 1.7e-143 477.5 0.0 4.8e-143 476.0 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG13651.1 - 9.5e-116 387.2 6.9 9.5e-116 387.2 6.9 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG13651.1 - 1.5e-89 299.8 0.1 3.7e-89 298.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KEG13651.1 - 5e-76 254.7 4.0 1.7e-75 253.0 4.0 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 KEG13651.1 - 7e-73 245.5 1.3 3.1e-72 243.4 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KEG13651.1 - 4.4e-54 182.7 0.5 8.3e-50 168.8 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG13651.1 - 4e-44 150.3 0.0 3e-42 144.2 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 KEG13651.1 - 6.3e-40 137.2 4.9 1.6e-39 136.0 4.9 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KEG13651.1 - 1.3e-37 128.6 0.5 6.1e-37 126.4 0.1 2.5 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KEG13651.1 - 9.5e-16 58.1 0.3 0.00027 21.0 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KEG13651.1 - 1.8e-15 57.2 0.1 1.6e-14 54.1 0.1 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KEG13651.1 - 1.6e-13 50.7 0.2 6.6e-12 45.5 0.1 3.6 2 1 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KEG13651.1 - 1.6e-06 28.6 0.1 0.037 14.5 0.0 5.0 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG13651.1 - 5.5e-06 26.7 0.3 0.4 11.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KEG13651.1 - 0.0056 17.2 0.0 0.24 11.9 0.0 3.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KEG13651.1 - 0.029 14.0 3.0 12 5.4 0.1 4.0 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain SNF5 PF04855.12 KEG13651.1 - 0.03 14.1 0.1 7.7 6.2 0.1 3.0 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 Sec34 PF04136.15 KEG13651.1 - 1.2 9.0 12.5 2.6 7.9 0.0 5.0 5 0 0 5 5 4 0 Sec34-like family EF-hand_6 PF13405.6 KEG13652.1 - 3.2e-10 39.1 0.0 0.01 15.7 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KEG13652.1 - 7.1e-09 36.0 0.9 0.058 13.8 0.2 4.7 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG13652.1 - 3.6e-06 26.1 0.0 0.15 11.6 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KEG13652.1 - 0.00023 20.5 0.0 0.099 12.2 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KEG13652.1 - 0.0031 17.3 0.0 1.1 9.2 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair HTH_11 PF08279.12 KEG13652.1 - 0.021 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 HTH domain CBF_beta PF02312.17 KEG13652.1 - 0.074 12.7 3.0 0.2 11.3 3.0 1.7 1 0 0 1 1 1 0 Core binding factor beta subunit Adeno_E3 PF06040.11 KEG13652.1 - 0.36 11.0 1.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 protein Tubulin PF00091.25 KEG13653.1 - 2e-66 224.0 0.0 3e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEG13653.1 - 4.5e-45 152.9 0.5 8.9e-45 151.9 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KEG13653.1 - 3.8e-05 24.0 0.0 0.00016 22.0 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KEG13653.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like PUB PF09409.10 KEG13654.1 - 3.2e-12 46.2 0.0 5.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 PUB domain Mac PF12464.8 KEG13654.1 - 0.00026 21.2 0.0 0.24 11.7 0.1 2.7 2 0 0 2 2 2 2 Maltose acetyltransferase Ank_2 PF12796.7 KEG13656.1 - 2.2e-19 69.8 0.1 5.5e-09 36.5 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEG13656.1 - 8e-17 60.9 0.6 0.0076 16.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KEG13656.1 - 9.2e-17 61.2 2.0 1.8e-10 41.1 0.0 3.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG13656.1 - 2.7e-15 54.9 0.9 8.9e-05 22.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KEG13656.1 - 3.8e-15 55.8 5.5 1.3e-09 38.1 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SLBP_RNA_bind PF15247.6 KEG13657.1 - 5.9e-20 71.2 0.4 1.2e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Methyltransf_23 PF13489.6 KEG13659.1 - 1.7e-20 73.5 0.0 2.8e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG13659.1 - 3.3e-17 62.7 0.0 6.9e-17 61.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG13659.1 - 9.6e-17 61.4 0.2 2.4e-16 60.1 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG13659.1 - 3.9e-14 53.1 0.4 1.6e-13 51.1 0.4 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG13659.1 - 3.5e-13 50.1 0.1 1.1e-12 48.5 0.1 1.9 2 1 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 KEG13659.1 - 3.5e-10 39.6 0.0 6.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KEG13659.1 - 4.3e-08 32.9 0.0 6.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KEG13659.1 - 3.7e-07 30.0 0.1 4.3e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 KEG13659.1 - 7.2e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KEG13659.1 - 1.4e-06 27.9 0.0 3.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB Pox_MCEL PF03291.16 KEG13659.1 - 5.8e-05 22.4 0.0 8.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.18 KEG13659.1 - 6.2e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KEG13659.1 - 0.00057 19.1 0.0 0.0016 17.6 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 KEG13659.1 - 0.0006 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KEG13659.1 - 0.0016 18.1 0.1 0.0037 16.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KEG13659.1 - 0.0047 16.5 0.4 0.01 15.5 0.4 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 KEG13659.1 - 0.0087 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) FYVE PF01363.21 KEG13660.1 - 1.4e-16 60.4 13.1 4.2e-15 55.6 7.8 2.7 2 0 0 2 2 2 2 FYVE zinc finger DZR PF12773.7 KEG13660.1 - 2.3 8.3 16.1 1.1e+02 3.0 15.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon SRP-alpha_N PF04086.13 KEG13660.1 - 4 7.3 28.0 5.3 6.9 28.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOBP PF15279.6 KEG13660.1 - 4.7 7.7 11.6 6.8 7.2 11.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.11 KEG13660.1 - 8.1 6.4 36.8 11 6.1 36.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SKG6 PF08693.10 KEG13661.1 - 0.0028 17.0 0.4 0.0028 17.0 0.4 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain SAS-6_N PF16531.5 KEG13662.1 - 4.4e-19 68.9 0.0 1.2e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Taxilin PF09728.9 KEG13662.1 - 0.00032 20.0 15.1 0.00032 20.0 15.1 3.1 2 1 1 3 3 3 1 Myosin-like coiled-coil protein DUF5082 PF16888.5 KEG13662.1 - 0.0031 17.8 10.3 0.0031 17.8 10.3 3.5 1 1 2 4 4 4 1 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 KEG13662.1 - 0.0038 17.3 2.2 0.0038 17.3 2.2 3.9 1 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 KEG13662.1 - 0.15 11.8 49.1 0.73 9.5 28.7 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 KEG13662.1 - 0.81 9.9 64.3 0.97 9.6 26.1 4.4 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KEG13662.1 - 0.82 8.5 55.3 0.6 8.9 8.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 KEG13662.1 - 1.2 8.5 55.1 0.4 10.0 13.3 4.1 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 KEG13662.1 - 4.2 5.6 55.1 0.18 10.1 35.1 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein MT PF12777.7 KEG13663.1 - 7.1e-05 22.0 0.8 7.1e-05 22.0 0.8 2.2 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor adh_short_C2 PF13561.6 KEG13663.1 - 0.088 12.3 0.1 0.34 10.4 0.1 1.9 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sgf11_N PF18519.1 KEG13663.1 - 0.14 11.7 0.2 0.51 9.9 0.2 2.0 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain DUF2353 PF09789.9 KEG13664.1 - 0.26 10.6 3.3 0.34 10.2 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4633 PF15464.6 KEG13664.1 - 1.5 9.0 5.8 0.25 11.5 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Hydrolase_6 PF13344.6 KEG13666.1 - 1.9e-20 72.8 0.0 3.8e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEG13666.1 - 1.1e-12 47.8 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4191 PF13829.6 KEG13666.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4121 PF13497.6 KEG13666.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PIH1 PF08190.12 KEG13667.1 - 3.4e-58 195.8 1.4 7e-58 194.8 1.4 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KEG13667.1 - 3.1e-21 75.6 0.3 3.1e-21 75.6 0.3 1.8 2 0 0 2 2 2 1 PIH1 CS-like domain PGAP1 PF07819.13 KEG13669.1 - 1.1e-10 41.7 0.0 0.00037 20.3 0.1 2.7 2 1 0 2 2 2 2 PGAP1-like protein Hydrolase_4 PF12146.8 KEG13669.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TMEM132D_C PF15706.5 KEG13669.1 - 2.6 7.9 16.3 0.026 14.3 7.1 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1744 PF08490.12 KEG13670.1 - 1.3e-54 185.3 0.0 5.4e-53 180.0 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KEG13670.1 - 1.6e-53 182.1 0.1 2.7e-53 181.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KEG13670.1 - 8e-14 51.2 0.4 7.4e-12 44.7 0.2 3.5 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KEG13670.1 - 2.6e-09 37.1 1.6 9e-08 32.0 0.4 3.1 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KEG13670.1 - 5.6e-07 29.7 0.0 2.1e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily Cytochrome_C7 PF14522.6 KEG13670.1 - 0.0044 17.0 3.0 0.011 15.7 3.0 1.6 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 KEG13670.1 - 0.08 13.4 3.0 0.26 11.8 3.0 1.8 1 0 0 1 1 1 0 Cytochrome c3 zf-DNA_Pol PF08996.10 KEG13670.1 - 1.1 9.0 5.1 2.5 7.8 5.1 1.6 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-CHY PF05495.12 KEG13670.1 - 2.1 8.9 6.8 6.6 7.3 6.8 1.9 1 0 0 1 1 1 0 CHY zinc finger zf-3CxxC PF13695.6 KEG13671.1 - 8.8e-08 32.5 1.0 1.1e-07 32.3 1.0 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 KEG13671.1 - 3.2e-06 27.8 2.8 5.6e-06 27.0 2.8 1.4 1 1 0 1 1 1 1 Zinc-binding domain HypA PF01155.19 KEG13671.1 - 0.037 14.0 0.2 0.053 13.5 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LolA_like PF17131.4 KEG13671.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 1 0 1 1 1 0 Outer membrane lipoprotein-sorting protein zinc_ribbon_4 PF13717.6 KEG13671.1 - 0.75 9.8 4.9 1 9.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KEG13672.1 - 4.8e-09 35.9 4.5 8.4e-09 35.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG13672.1 - 6.2e-07 29.6 8.0 1.2e-06 28.8 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEG13672.1 - 5e-06 26.3 3.2 9.2e-06 25.4 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG13672.1 - 1.8e-05 24.6 3.1 3.1e-05 23.8 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEG13672.1 - 3.8e-05 23.4 5.0 7.8e-05 22.4 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG13672.1 - 0.0011 18.8 5.3 0.0022 17.8 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEG13672.1 - 0.0026 17.8 6.4 0.0057 16.7 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KEG13672.1 - 0.003 17.3 4.1 0.0058 16.4 4.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KEG13672.1 - 0.014 15.5 4.0 0.033 14.3 4.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Phage_holin_2_4 PF16082.5 KEG13672.1 - 0.1 12.3 2.1 0.13 12.0 0.2 2.1 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Rtf2 PF04641.12 KEG13672.1 - 0.34 10.2 0.2 0.53 9.6 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger LisH PF08513.11 KEG13673.1 - 0.00068 19.5 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 LisH Glucokinase PF02685.16 KEG13673.1 - 0.21 10.6 0.2 0.24 10.3 0.2 1.1 1 0 0 1 1 1 0 Glucokinase Thioredoxin_11 PF18078.1 KEG13674.1 - 0.16 12.1 0.2 0.25 11.4 0.2 1.2 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain 14-3-3 PF00244.20 KEG13675.1 - 7.2e-88 293.8 5.3 8.2e-88 293.6 5.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_2 PF07719.17 KEG13675.1 - 0.0095 16.0 2.6 0.81 10.0 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13675.1 - 0.047 13.9 1.4 32 5.1 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13675.1 - 0.069 13.0 2.1 0.4 10.6 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat OPA3 PF07047.12 KEG13676.1 - 1.3e-07 31.4 0.1 1.7e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) OPA3 PF07047.12 KEG13677.1 - 1.7e-10 40.8 0.3 1.9e-10 40.6 0.3 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) BRI3BP PF14965.6 KEG13677.1 - 0.014 14.9 0.3 0.018 14.6 0.3 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 TRAF_BIRC3_bd PF16673.5 KEG13677.1 - 0.036 13.9 1.0 0.063 13.1 1.0 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Baculo_PEP_C PF04513.12 KEG13677.1 - 0.039 14.0 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 KEG13678.1 - 0.0036 17.0 25.7 0.0036 17.0 25.7 3.1 2 1 1 3 3 3 2 Intermediate filament protein PKcGMP_CC PF16808.5 KEG13678.1 - 1 9.3 18.0 1.1 9.2 0.7 5.4 3 2 3 6 6 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase 2_5_RNA_ligase2 PF13563.6 KEG13679.1 - 0.089 12.7 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily DUF2779 PF11074.8 KEG13680.1 - 3.9e-40 137.2 0.0 7.7e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DDHD PF02862.17 KEG13680.1 - 0.093 12.9 0.7 1 9.5 0.4 2.2 2 0 0 2 2 2 0 DDHD domain TTL PF03133.15 KEG13682.1 - 1.1e-68 231.5 0.1 1.8e-68 230.8 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG13682.1 - 1.7e-09 37.3 1.1 9e-05 21.8 0.0 4.3 3 1 1 4 4 4 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KEG13682.1 - 3.4e-05 23.2 0.0 0.033 13.4 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KEG13682.1 - 0.15 12.1 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Ribosomal_L36e PF01158.18 KEG13682.1 - 0.25 11.6 2.4 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L36e ATG16 PF08614.11 KEG13683.1 - 0.011 16.0 0.4 0.011 16.0 0.4 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) BOP1NT PF08145.12 KEG13684.1 - 2.6e-76 257.0 6.9 3.8e-76 256.5 6.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KEG13684.1 - 2.6e-15 56.5 4.6 5.3e-07 30.2 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13684.1 - 5.8e-06 26.5 0.0 0.0027 18.0 0.0 4.2 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG13684.1 - 0.12 11.3 0.0 0.97 8.3 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RCC1 PF00415.18 KEG13686.1 - 1.6e-33 115.0 17.6 1.1e-14 54.7 0.1 7.1 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG13686.1 - 2.1e-16 59.2 12.2 6.3e-05 22.7 0.3 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Defensin_propep PF00879.18 KEG13686.1 - 0.61 10.4 5.5 1.4 9.3 5.5 1.5 1 0 0 1 1 1 0 Defensin propeptide LRR_4 PF12799.7 KEG13688.1 - 6.7e-10 39.1 9.7 0.03 14.8 0.3 5.5 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG13688.1 - 1.6e-08 34.2 7.2 0.0055 16.4 0.3 4.0 3 0 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KEG13688.1 - 8.9e-07 28.6 0.1 8.1e-05 22.2 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KEG13688.1 - 0.0046 16.9 11.1 3.4 8.0 0.1 5.8 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KEG13688.1 - 0.069 13.7 7.2 1.7e+02 3.4 0.1 6.9 6 3 0 6 6 6 0 Leucine Rich Repeat tRNA-synt_1f PF01921.18 KEG13689.1 - 0.0076 15.2 0.3 0.014 14.3 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) WD40 PF00400.32 KEG13689.1 - 0.012 16.4 14.3 0.059 14.3 0.2 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat ABC_transp_aux PF09822.9 KEG13689.1 - 0.19 11.2 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system DUF3287 PF11690.8 KEG13689.1 - 0.43 10.3 3.6 1 9.1 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DNA_ligase_A_M PF01068.21 KEG13690.1 - 6.1e-06 26.0 0.0 0.017 14.8 0.2 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 KEG13690.1 - 0.053 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 DNA ligase OB-like domain DUF3218 PF11508.8 KEG13690.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) PUF PF00806.19 KEG13691.1 - 5e-14 51.1 0.4 2.8 7.8 0.0 8.9 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat DUF3549 PF12069.8 KEG13691.1 - 0.038 13.1 0.2 0.038 13.1 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3549) Telomerase_RBD PF12009.8 KEG13691.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain TPR_MLP1_2 PF07926.12 KEG13692.1 - 0.03 14.4 0.3 0.034 14.2 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APH PF01636.23 KEG13692.1 - 0.048 13.6 1.2 0.05 13.5 1.2 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_AsnC-type PF13404.6 KEG13692.1 - 0.083 12.7 2.9 0.23 11.3 0.1 2.4 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain CLZ PF16526.5 KEG13692.1 - 0.098 13.0 1.2 0.23 11.9 0.6 1.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Peptidase_M32 PF02074.15 KEG13693.1 - 6e-37 127.6 0.0 6.6e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase PYC_OADA PF02436.18 KEG13693.1 - 0.19 11.4 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain Peptidase_M32 PF02074.15 KEG13694.1 - 2.9e-169 563.9 0.0 3.3e-169 563.7 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Kinesin PF00225.23 KEG13695.1 - 3.8e-101 338.3 0.0 5.1e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG13695.1 - 9.8e-15 54.8 0.0 3.8e-14 52.9 0.0 2.0 1 1 1 2 2 2 1 Microtubule binding Ras PF00071.22 KEG13695.1 - 7e-05 22.5 0.0 0.00082 19.0 0.0 2.5 2 0 0 2 2 2 1 Ras family FHA PF00498.26 KEG13695.1 - 0.00028 21.2 0.0 0.00083 19.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Roc PF08477.13 KEG13695.1 - 0.007 16.6 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Kinesin_assoc PF16183.5 KEG13695.1 - 0.014 15.6 0.1 0.036 14.2 0.1 1.7 1 0 0 1 1 1 0 Kinesin-associated AAA_29 PF13555.6 KEG13695.1 - 0.044 13.5 0.0 1.9 8.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain COR PF16095.5 KEG13695.1 - 0.078 12.8 0.2 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 C-terminal of Roc, COR, domain MMR_HSR1 PF01926.23 KEG13695.1 - 0.14 12.2 0.0 24 5.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Peptidase_M17 PF00883.21 KEG13696.1 - 1.1e-91 307.4 0.0 1.4e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 KEG13696.1 - 8e-38 129.4 0.4 1.7e-37 128.4 0.4 1.6 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 Frag1 PF10277.9 KEG13698.1 - 8.6e-38 130.1 12.2 8.6e-38 130.1 12.2 3.7 4 1 0 4 4 4 1 Frag1/DRAM/Sfk1 family TMEM52 PF14979.6 KEG13699.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Transmembrane 52 Shisa PF13908.6 KEG13699.1 - 0.034 14.4 2.1 0.06 13.6 2.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KEG13699.1 - 0.2 12.5 0.2 0.62 11.0 0.2 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Prominin PF05478.11 KEG13699.1 - 0.23 9.4 1.4 0.29 9.0 1.4 1.0 1 0 0 1 1 1 0 Prominin TBCC PF07986.12 KEG13700.1 - 6.1e-30 103.4 0.4 1.1e-29 102.6 0.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C AAA_6 PF12774.7 KEG13701.1 - 3e-125 417.5 0.2 3.2e-124 414.2 0.1 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG13701.1 - 9.1e-105 351.0 5.8 9.1e-105 351.0 5.8 5.4 4 2 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KEG13701.1 - 3.5e-65 219.2 0.9 3.5e-65 219.2 0.9 4.3 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KEG13701.1 - 1.3e-47 162.4 0.0 1.3e-47 162.4 0.0 4.0 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 KEG13701.1 - 3.2e-34 118.1 0.0 6.8e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KEG13701.1 - 4.4e-30 104.9 9.8 8.5e-30 103.9 9.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KEG13701.1 - 4.7e-30 104.4 0.6 3.2e-18 66.0 0.0 5.8 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEG13701.1 - 3.7e-29 101.5 0.2 2.2e-24 86.0 0.0 4.4 5 0 0 5 5 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 KEG13701.1 - 1.1e-27 96.5 0.0 6.4e-27 94.0 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 KEG13701.1 - 2.1e-18 66.6 0.0 1.6e-17 63.7 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 KEG13701.1 - 1.2e-14 55.0 6.4 0.00026 21.4 0.0 7.0 6 0 0 6 6 5 3 AAA ATPase domain AAA_22 PF13401.6 KEG13701.1 - 2.6e-10 40.7 4.3 0.053 13.8 0.0 6.3 5 1 0 5 5 5 2 AAA domain AAA PF00004.29 KEG13701.1 - 5.5e-10 39.8 6.8 0.028 14.9 0.0 6.7 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEG13701.1 - 3.6e-05 23.6 0.0 0.12 12.1 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 KEG13701.1 - 7.9e-05 23.2 2.6 0.0085 16.6 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 KEG13701.1 - 0.00018 21.3 0.6 0.17 11.6 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 KEG13701.1 - 0.00031 21.0 5.0 0.042 14.1 0.0 5.4 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 KEG13701.1 - 0.00043 20.6 0.8 3.9 7.9 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_29 PF13555.6 KEG13701.1 - 0.00099 18.8 0.0 0.039 13.7 0.0 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KEG13701.1 - 0.0018 18.4 5.1 0.017 15.3 0.0 3.9 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 KEG13701.1 - 0.0023 18.4 0.0 0.0023 18.4 0.0 4.8 6 0 0 6 6 2 1 ABC transporter AAA_21 PF13304.6 KEG13701.1 - 0.0032 17.3 0.0 0.011 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEG13701.1 - 0.004 17.1 0.0 0.004 17.1 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase AAA_14 PF13173.6 KEG13701.1 - 0.0053 16.8 0.0 52 3.9 0.0 4.8 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KEG13701.1 - 0.019 14.9 0.1 2 8.3 0.0 3.5 3 0 0 3 3 2 0 NACHT domain IstB_IS21 PF01695.17 KEG13701.1 - 0.084 12.6 0.3 2 8.1 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEG13701.1 - 0.098 12.0 1.3 12 5.2 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KEG13701.1 - 0.2 12.1 7.5 3.9 7.9 0.0 4.4 4 0 0 4 4 2 0 AAA domain Rad17 PF03215.15 KEG13701.1 - 0.84 9.5 12.9 0.48 10.3 0.0 5.1 6 0 0 6 6 5 0 Rad17 P-loop domain AAA_23 PF13476.6 KEG13701.1 - 1 9.8 0.0 1 9.8 0.0 6.5 7 0 0 7 7 4 0 AAA domain TTL PF03133.15 KEG13702.1 - 1.9e-39 135.6 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SPW PF03779.14 KEG13703.1 - 0.31 10.7 1.8 20 4.8 0.0 2.5 2 0 0 2 2 2 0 SPW repeat UQ_con PF00179.26 KEG13705.1 - 6.4e-05 22.6 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 KEG13706.1 - 3.6e-43 146.6 0.0 4.4e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KEG13706.1 - 0.0029 17.4 0.1 0.0055 16.6 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KEG13706.1 - 0.044 14.1 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain HMG_CoA_synt_N PF01154.17 KEG13708.1 - 1.2e-11 44.8 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KEG13708.1 - 1.2e-07 31.6 0.1 0.00063 19.4 0.0 2.9 3 0 0 3 3 3 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 KEG13708.1 - 0.0086 15.9 0.2 0.02 14.7 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1726 PF08351.11 KEG13708.1 - 0.033 14.1 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Porin_5 PF16930.5 KEG13710.1 - 0.052 12.0 0.5 0.072 11.6 0.5 1.1 1 0 0 1 1 1 0 Putative porin Kelch_4 PF13418.6 KEG13711.1 - 7.9e-48 160.3 2.1 1.2e-07 31.6 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KEG13711.1 - 3.2e-42 142.1 6.7 9.8e-08 32.1 0.0 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG13711.1 - 2.8e-41 138.8 15.5 3e-08 33.1 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KEG13711.1 - 1.1e-32 111.5 11.6 2.4e-06 27.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KEG13711.1 - 3e-32 109.8 2.3 1.5e-05 25.1 0.0 6.6 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KEG13711.1 - 1e-23 82.3 12.8 3.4e-06 26.8 0.0 6.8 6 2 0 6 6 6 6 Kelch motif Ribosomal_S8e PF01201.22 KEG13712.1 - 3.1e-43 147.2 3.6 4e-43 146.9 3.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Transketolase_N PF00456.21 KEG13713.1 - 2.1e-140 467.4 0.0 2.9e-140 467.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEG13713.1 - 2.3e-44 151.2 0.0 4.2e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEG13713.1 - 3.1e-08 33.6 0.0 6.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KEG13713.1 - 0.0027 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEG13713.1 - 0.007 15.6 0.0 0.025 13.8 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Lant_dehydr_C PF14028.6 KEG13713.1 - 0.14 11.7 0.2 0.49 9.9 0.1 1.8 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Ribosomal_L26 PF16906.5 KEG13714.1 - 1.3e-37 128.1 1.3 1.8e-37 127.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KEG13714.1 - 6.9e-06 25.8 0.3 2.3e-05 24.2 0.3 2.0 1 1 0 1 1 1 1 KOW motif MutL_C PF08676.11 KEG13715.1 - 1.1e-29 103.0 0.0 2.5e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KEG13715.1 - 4.8e-15 55.3 0.0 4.1e-14 52.3 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KEG13715.1 - 2.2e-08 34.0 0.9 1e-07 31.9 0.9 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEG13715.1 - 0.014 15.9 0.1 0.03 14.8 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DivIC PF04977.15 KEG13716.1 - 0.0016 18.1 0.3 0.0016 18.1 0.3 8.2 7 3 2 9 9 9 1 Septum formation initiator YabA PF06156.13 KEG13716.1 - 0.032 14.9 1.1 0.032 14.9 1.1 6.9 2 1 2 5 5 5 0 Initiation control protein YabA HALZ PF02183.18 KEG13716.1 - 0.12 12.6 0.3 0.12 12.6 0.3 6.0 6 0 0 6 6 6 0 Homeobox associated leucine zipper TPMT PF05724.11 KEG13718.1 - 2.5e-21 76.3 0.2 3.7e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KEG13718.1 - 0.0025 18.5 0.0 0.23 12.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain CPBP PF02517.16 KEG13719.1 - 0.064 13.6 0.1 0.097 13.0 0.1 1.4 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease Laminin_G_3 PF13385.6 KEG13721.1 - 7.7e-14 52.1 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CBF PF03914.17 KEG13721.1 - 0.031 14.3 0.0 4.2 7.4 0.0 3.2 3 0 0 3 3 3 0 CBF/Mak21 family DUF5578 PF17741.1 KEG13721.1 - 0.037 13.5 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5578) Aldedh PF00171.22 KEG13723.1 - 1.4e-100 337.0 0.0 1.7e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-CCHC PF00098.23 KEG13724.1 - 2.9e-07 30.3 0.6 8.2e-07 28.8 0.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH PF00642.24 KEG13724.1 - 5.8e-07 29.3 11.1 0.00015 21.6 2.5 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG13724.1 - 6e-07 29.3 7.6 0.0024 17.9 1.2 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCHC_2 PF13696.6 KEG13724.1 - 0.00073 19.3 2.7 0.0015 18.3 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Torus PF16131.5 KEG13724.1 - 0.0011 19.7 8.9 0.12 13.0 0.4 2.7 2 1 1 3 3 3 2 Torus domain RRM_1 PF00076.22 KEG13724.1 - 0.012 15.4 0.0 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 KEG13724.1 - 0.1 12.5 9.6 0.79 9.6 1.5 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger RPS31 PF17067.5 KEG13724.1 - 0.22 11.7 1.1 0.42 10.8 1.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S31e zf-CCHC_5 PF14787.6 KEG13724.1 - 1.7 8.4 7.7 0.19 11.4 1.1 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF3915 PF13054.6 KEG13724.1 - 6.8 6.7 6.4 2 8.4 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) zf-C2H2_3 PF13878.6 KEG13725.1 - 1.3e-10 40.9 0.3 3.3e-10 39.6 0.3 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO ABC_tran PF00005.27 KEG13726.1 - 8.5e-47 159.1 1.0 1.1e-21 77.7 0.0 3.7 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KEG13726.1 - 3.1e-26 91.2 8.0 3.1e-26 91.2 8.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KEG13726.1 - 1.1e-17 64.8 10.4 1e-05 25.5 1.4 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEG13726.1 - 7.3e-09 36.2 2.4 0.00028 21.3 0.1 2.8 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 KEG13726.1 - 6.7e-08 32.2 3.1 0.05 13.0 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEG13726.1 - 7.7e-06 25.6 0.2 0.19 11.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEG13726.1 - 3.7e-05 23.8 0.2 0.34 11.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG13726.1 - 0.00017 21.5 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 KEG13726.1 - 0.0025 17.7 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KEG13726.1 - 0.0027 18.3 6.0 0.026 15.1 0.0 4.2 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 KEG13726.1 - 0.0028 17.4 0.0 0.87 9.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEG13726.1 - 0.0029 17.9 4.2 0.02 15.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 KEG13726.1 - 0.0043 17.5 0.0 0.59 10.6 0.0 3.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEG13726.1 - 0.0045 17.2 6.0 0.59 10.3 0.1 3.9 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.6 KEG13726.1 - 0.0071 16.9 17.0 0.014 16.0 0.1 4.4 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 KEG13726.1 - 0.008 16.4 5.2 0.15 12.3 0.2 3.9 3 3 1 4 4 4 1 AAA domain AAA_24 PF13479.6 KEG13726.1 - 0.0094 15.7 0.5 2 8.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KEG13726.1 - 0.018 14.0 1.4 0.92 8.4 0.0 3.0 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KEG13726.1 - 0.033 14.2 1.6 13 5.8 0.0 3.9 4 0 0 4 4 4 0 Dynamin family PduV-EutP PF10662.9 KEG13726.1 - 0.049 13.4 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KEG13726.1 - 0.054 13.7 0.0 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KEG13726.1 - 0.06 12.9 0.4 8.5 5.9 0.1 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KEG13726.1 - 0.084 13.3 1.9 18 5.8 0.0 3.4 4 0 0 4 4 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 KEG13726.1 - 0.094 12.0 0.2 4.4 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 KEG13726.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CUE PF02845.16 KEG13726.1 - 0.11 12.2 0.3 1.7 8.4 0.0 3.0 4 0 0 4 4 3 0 CUE domain AAA_5 PF07728.14 KEG13726.1 - 0.12 12.4 0.9 2.3 8.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEG13726.1 - 0.13 11.8 0.0 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KEG13726.1 - 0.14 10.8 0.0 0.14 10.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 KEG13726.1 - 0.46 10.1 13.9 0.31 10.7 1.1 4.7 4 1 0 4 4 4 0 AAA ATPase domain U1snRNP70_N PF12220.8 KEG13726.1 - 0.86 10.3 8.8 2.8 8.6 1.0 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4558 PF15104.6 KEG13727.1 - 0.00013 22.0 2.9 0.00017 21.6 2.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) Acetyltransf_1 PF00583.25 KEG13728.1 - 2.1e-09 37.6 0.1 3.2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEG13728.1 - 5.7e-08 33.1 0.1 8.3e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEG13728.1 - 7.8e-08 32.3 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEG13728.1 - 0.00031 20.8 0.1 0.00053 20.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG13728.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 KEG13728.1 - 0.06 13.3 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase zf-C3HC4_2 PF13923.6 KEG13728.1 - 0.091 12.6 0.6 0.21 11.5 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TACI-CRD2 PF09305.10 KEG13728.1 - 0.31 11.1 2.9 7 6.8 0.1 2.6 2 0 0 2 2 2 0 TACI, cysteine-rich domain LRR_4 PF12799.7 KEG13729.1 - 1.2e-13 51.0 6.0 5.4e-06 26.7 0.1 4.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG13729.1 - 1.8e-10 40.6 1.3 2.7e-08 33.5 0.1 2.5 1 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 KEG13729.1 - 4.6e-10 39.1 15.0 0.00017 21.3 0.5 3.9 3 1 1 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KEG13729.1 - 0.00029 20.6 6.9 1.2 9.4 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich repeat ATG16 PF08614.11 KEG13729.1 - 0.00098 19.4 11.3 0.00098 19.4 11.3 3.4 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) FNIP PF05725.12 KEG13729.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 FNIP Repeat RPA43_OB PF17875.1 KEG13729.1 - 0.83 10.3 6.6 0.43 11.2 0.8 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Spt20 PF12090.8 KEG13729.1 - 1.9 8.1 35.2 1.8 8.1 8.7 2.5 2 0 0 2 2 2 0 Spt20 family LRR_1 PF00560.33 KEG13729.1 - 3.6 8.5 10.4 30 5.7 0.0 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat CH PF00307.31 KEG13730.1 - 0.00049 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF720 PF05302.11 KEG13730.1 - 0.0015 18.4 0.1 0.0045 16.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF720) HALZ PF02183.18 KEG13730.1 - 0.092 13.0 2.6 0.31 11.3 0.1 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper PKcGMP_CC PF16808.5 KEG13730.1 - 6 6.8 11.1 3.8 7.4 2.0 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CtaG_Cox11 PF04442.14 KEG13731.1 - 2.8e-47 160.5 0.4 4.4e-47 159.9 0.2 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_primase_lrg PF04104.14 KEG13732.1 - 8.4e-83 277.8 0.0 1.1e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Acyltransferase PF01553.21 KEG13733.1 - 1e-12 47.8 0.0 3.2e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase zf_UBZ PF18439.1 KEG13733.1 - 0.0024 17.4 0.2 0.0048 16.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Reticulon PF02453.17 KEG13733.1 - 0.0065 16.5 0.4 0.019 14.9 0.4 1.8 1 0 0 1 1 1 1 Reticulon Met_10 PF02475.16 KEG13735.1 - 8.8e-40 136.6 0.0 2.5e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein MTS PF05175.14 KEG13735.1 - 6.7e-05 22.5 0.1 0.00015 21.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KEG13735.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KEG13735.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 KEG13735.1 - 0.051 12.6 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DNA_methylase PF00145.17 KEG13735.1 - 0.053 12.9 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase DSPc PF00782.20 KEG13736.1 - 9.2e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KEG13736.1 - 0.00017 21.6 0.2 0.00032 20.8 0.2 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEG13736.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTEN_C2 PF10409.9 KEG13736.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.6 KEG13736.1 - 0.084 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myosin_head PF00063.21 KEG13737.1 - 4.5e-194 646.5 0.2 6.8e-194 645.9 0.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 KEG13737.1 - 6.3e-05 22.4 1.7 0.0027 17.4 0.8 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_29 PF13555.6 KEG13737.1 - 0.037 13.8 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEG13737.1 - 0.074 13.3 0.1 0.65 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KEG13737.1 - 0.078 13.4 0.3 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 KEG13737.1 - 0.097 12.2 0.0 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain 2-Hacid_dh_C PF02826.19 KEG13738.1 - 2.4e-10 40.0 0.0 2.8e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_6 PF13516.6 KEG13741.1 - 1.9e-30 102.3 35.5 5.4e-05 22.9 0.2 12.7 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 KEG13741.1 - 1.1e-08 35.2 15.1 0.017 15.5 3.9 6.6 5 2 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG13741.1 - 0.00043 20.5 14.3 20 6.2 0.0 9.1 9 3 0 9 9 9 0 Leucine Rich Repeat DUF3450 PF11932.8 KEG13741.1 - 0.004 16.5 9.1 0.004 16.5 9.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) LRR_8 PF13855.6 KEG13741.1 - 0.011 15.5 24.8 0.075 12.8 0.8 7.7 6 3 3 9 9 9 0 Leucine rich repeat DUF1664 PF07889.12 KEG13741.1 - 1.3 9.1 11.2 1.8 8.6 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KEG13741.1 - 1.4 9.2 12.5 0.38 11.1 4.7 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF2935 PF11155.8 KEG13741.1 - 1.9 8.8 5.6 13 6.1 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) Cnn_1N PF07989.11 KEG13741.1 - 2 8.6 12.7 8.6 6.6 4.2 3.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 IU_nuc_hydro PF01156.19 KEG13742.1 - 1.2e-48 166.3 0.0 1.5e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase UPF0370 PF13980.6 KEG13743.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Mito_carr PF00153.27 KEG13744.1 - 3.9e-56 187.0 3.3 1.9e-19 69.4 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Trypsin_2 PF13365.6 KEG13745.1 - 0.0014 19.6 6.2 0.055 14.4 6.2 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S29 PF02907.15 KEG13745.1 - 0.02 14.6 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease TPR_19 PF14559.6 KEG13746.1 - 9.6e-13 48.4 0.0 0.00036 21.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13746.1 - 1.3e-08 34.3 24.3 0.025 14.7 0.2 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG13746.1 - 1.8e-08 34.5 19.4 0.0085 16.3 0.0 5.9 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KEG13746.1 - 6.3e-07 29.7 5.3 0.51 11.3 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13746.1 - 6.4e-06 26.7 2.6 0.91 10.2 0.1 5.3 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13746.1 - 9.7e-05 22.0 11.1 0.36 10.7 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KEG13746.1 - 0.00064 19.2 4.3 0.27 10.6 1.3 3.4 3 0 0 3 3 3 2 Coatomer epsilon subunit TPR_6 PF13174.6 KEG13746.1 - 0.0035 17.9 4.5 37 5.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEG13746.1 - 0.0047 17.4 0.0 3.6 8.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG13746.1 - 0.011 15.7 6.3 0.11 12.6 0.3 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG13746.1 - 0.013 15.8 10.4 0.39 11.0 0.1 5.6 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13746.1 - 0.019 15.1 0.2 0.76 10.0 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CDT1_C PF16679.5 KEG13746.1 - 0.036 14.5 0.2 0.26 11.7 0.0 2.4 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Fis1_TPR_C PF14853.6 KEG13746.1 - 5.4 7.2 10.6 6.5 6.9 0.3 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KEG13746.1 - 7.2 6.6 14.1 3.3 7.7 0.2 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEG13746.1 - 8.1 6.5 9.1 14 5.8 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Actin PF00022.19 KEG13747.1 - 3.9e-16 58.7 0.0 1.8e-07 30.1 0.0 3.0 1 1 2 3 3 3 2 Actin START PF01852.19 KEG13748.1 - 7.7e-30 103.9 0.0 1.6e-29 102.8 0.0 1.5 1 1 0 1 1 1 1 START domain DUF3074 PF11274.8 KEG13748.1 - 0.00063 19.8 0.0 0.0091 16.0 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Pkinase PF00069.25 KEG13749.1 - 3.3e-33 115.2 0.0 7.6e-33 114.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13749.1 - 6.6e-21 74.7 0.0 1.1e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEG13749.1 - 0.0042 16.5 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SSFA2_C PF14723.6 KEG13749.1 - 0.058 13.3 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Beta_helix PF13229.6 KEG13750.1 - 7e-24 84.5 12.5 5.4e-14 52.3 4.3 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KEG13750.1 - 9.8e-12 44.7 0.2 1.3e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 KEG13750.1 - 0.0069 16.3 0.2 0.2 11.5 0.0 2.2 1 1 1 2 2 2 1 Pectate lyase superfamily protein Hexapep PF00132.24 KEG13750.1 - 0.01 15.5 1.6 0.21 11.4 0.1 3.0 3 1 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF4957 PF16318.5 KEG13750.1 - 0.021 14.8 0.1 0.4 10.6 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4957) DUF1565 PF07602.11 KEG13750.1 - 0.027 13.8 0.3 0.19 11.1 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1565) DUF3253 PF11625.8 KEG13751.1 - 0.06 13.6 0.9 0.26 11.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3253) DUF2722 PF10846.8 KEG13752.1 - 0.00013 21.1 11.4 0.00015 20.8 11.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) zf-met PF12874.7 KEG13752.1 - 0.0037 17.6 0.1 0.0092 16.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Presenilin PF01080.17 KEG13752.1 - 0.016 14.0 5.3 0.018 13.9 5.3 1.2 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 KEG13752.1 - 0.019 15.3 2.4 0.038 14.3 2.4 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 KEG13752.1 - 0.02 14.4 4.3 0.027 13.9 4.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 KEG13752.1 - 0.024 14.4 3.2 0.031 14.1 3.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-C2H2_4 PF13894.6 KEG13752.1 - 0.036 14.9 0.1 0.087 13.7 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0560 PF10577.9 KEG13752.1 - 0.15 10.6 14.6 0.19 10.2 14.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FYDLN_acid PF09538.10 KEG13752.1 - 0.28 11.9 5.4 5.2 7.8 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) EMC3_TMCO1 PF01956.16 KEG13752.1 - 0.33 10.7 2.4 0.47 10.2 2.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spt20 PF12090.8 KEG13752.1 - 0.35 10.4 31.8 0.65 9.6 31.8 1.5 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 KEG13752.1 - 0.63 10.2 5.8 1.3 9.2 5.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 KEG13752.1 - 0.73 7.9 5.4 0.84 7.7 5.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2464 PF10240.9 KEG13752.1 - 0.78 9.3 5.6 1.3 8.5 5.6 1.5 1 0 0 1 1 1 0 Multivesicular body subunit 12 RR_TM4-6 PF06459.12 KEG13752.1 - 1 9.1 7.8 1.7 8.4 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 KEG13752.1 - 1.3 8.7 7.7 2.3 8.0 7.7 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2072 PF09845.9 KEG13752.1 - 1.4 9.2 6.4 47 4.3 0.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF4457 PF14652.6 KEG13752.1 - 1.8 7.7 5.7 2.4 7.3 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF4770 PF15994.5 KEG13752.1 - 2.1 8.6 21.5 0.32 11.2 12.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) PAT1 PF09770.9 KEG13752.1 - 2.4 6.4 20.8 2.6 6.2 20.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CTU2 PF10288.9 KEG13752.1 - 4.5 7.5 10.1 7.2 6.9 6.6 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Serinc PF03348.15 KEG13752.1 - 6.6 5.5 4.5 8.9 5.1 4.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EIIBC-GUT_N PF03612.14 KEG13752.1 - 6.9 6.4 9.4 13 5.4 9.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CLN3 PF02487.17 KEG13752.1 - 7.9 5.4 6.0 11 4.9 6.0 1.1 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 KEG13752.1 - 9.4 4.9 5.9 14 4.4 5.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 KEG13752.1 - 9.6 4.0 11.3 13 3.6 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PDEase_I PF00233.19 KEG13753.1 - 1.4e-54 185.3 0.0 3.4e-54 184.1 0.0 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 KEG13753.1 - 9.2e-07 28.9 17.4 2.3e-06 27.7 17.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger Pkinase PF00069.25 KEG13754.1 - 5e-62 209.6 0.6 8.3e-62 208.9 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13754.1 - 8.6e-40 136.7 0.2 1.5e-39 135.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG13754.1 - 7.2e-11 41.9 0.0 5.8e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KEG13754.1 - 0.0013 17.6 2.3 0.0025 16.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase TFIIA PF03153.13 KEG13754.1 - 0.01 15.9 5.7 0.014 15.5 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APH PF01636.23 KEG13754.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Spt20 PF12090.8 KEG13754.1 - 0.62 9.6 8.8 0.9 9.1 8.8 1.2 1 0 0 1 1 1 0 Spt20 family Helicase_C_2 PF13307.6 KEG13755.1 - 1.5e-48 165.2 0.0 3.2e-48 164.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KEG13755.1 - 1.9e-43 148.1 0.0 3.4e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 KEG13755.1 - 3.1e-05 23.8 0.0 0.00049 19.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG13755.1 - 8e-05 22.7 0.0 0.00052 20.0 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HBB PF06777.11 KEG13755.1 - 0.00081 19.1 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_11 PF13086.6 KEG13755.1 - 0.0072 16.1 0.5 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rotamase_3 PF13616.6 KEG13756.1 - 7.4e-22 78.1 0.0 1.6e-21 77.0 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KEG13756.1 - 7.5e-19 68.5 0.0 1.3e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KEG13756.1 - 8.2e-09 36.3 0.0 1.3e-08 35.7 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Cnd3 PF12719.7 KEG13757.1 - 5.5e-25 88.2 0.3 1e-22 80.7 0.0 2.6 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 KEG13757.1 - 0.00027 21.0 0.1 1.2 9.2 0.2 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEG13757.1 - 0.0005 20.4 2.9 0.044 14.2 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KEG13757.1 - 0.0072 16.5 8.4 6.1 7.4 0.6 5.5 4 0 0 4 4 4 2 HEAT repeat CLASP_N PF12348.8 KEG13757.1 - 0.03 13.9 0.4 0.79 9.2 0.1 2.8 2 0 0 2 2 2 0 CLASP N terminal Hjc PF01870.18 KEG13758.1 - 0.037 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Laminin_G_3 PF13385.6 KEG13759.1 - 7e-26 91.2 6.4 5e-20 72.2 0.0 5.0 5 1 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily Lectin_C PF00059.21 KEG13759.1 - 1.1e-10 42.2 0.1 6.4e-10 39.7 0.0 2.4 3 0 0 3 3 3 1 Lectin C-type domain WSC PF01822.19 KEG13759.1 - 1.8e-05 24.9 1.2 1.8e-05 24.9 1.2 3.5 3 0 0 3 3 3 1 WSC domain CHB_HEX_C_1 PF13290.6 KEG13759.1 - 0.039 14.0 0.1 0.17 12.0 0.1 2.2 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain PAN_4 PF14295.6 KEG13759.1 - 0.066 13.1 8.8 1.1 9.3 0.4 4.5 3 0 0 3 3 3 0 PAN domain ECSCR PF15820.5 KEG13759.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator ATP1G1_PLM_MAT8 PF02038.16 KEG13759.1 - 2.4 7.6 4.3 0.94 9.0 0.9 2.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family NCOA_u2 PF16665.5 KEG13760.1 - 0.13 12.6 2.8 0.23 11.8 2.8 1.5 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein DUF4407 PF14362.6 KEG13762.1 - 4.2 6.6 21.2 0.78 9.0 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) SUIM_assoc PF16619.5 KEG13763.1 - 0.13 12.3 2.3 0.31 11.1 2.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hist_deacetyl PF00850.19 KEG13764.1 - 6.6e-58 196.6 0.0 1.1e-57 195.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Caskin-Pro-rich PF16907.5 KEG13765.1 - 6.9 7.3 7.2 1.8 9.1 2.5 2.5 2 0 0 2 2 2 0 Proline rich region of Caskin proteins AAA_5 PF07728.14 KEG13766.1 - 1.3e-84 281.1 0.1 9e-30 103.5 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG13766.1 - 2.7e-08 34.4 0.2 0.0012 19.3 0.0 4.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KEG13766.1 - 3.2e-08 33.9 0.1 0.013 15.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KEG13766.1 - 1.5e-05 25.4 0.0 0.051 14.0 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEG13766.1 - 2.3e-05 24.1 0.0 0.22 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEG13766.1 - 3.3e-05 24.2 0.8 0.0027 18.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain MCM PF00493.23 KEG13766.1 - 4.1e-05 22.8 0.0 0.26 10.4 0.0 2.5 2 0 0 2 2 2 2 MCM P-loop domain AAA_14 PF13173.6 KEG13766.1 - 5e-05 23.3 0.0 0.0028 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEG13766.1 - 5.4e-05 22.8 0.0 0.023 14.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KEG13766.1 - 8.3e-05 22.4 0.2 0.75 9.5 0.1 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.12 KEG13766.1 - 0.00023 21.1 2.1 0.41 10.6 0.0 3.5 4 0 0 4 4 2 2 NACHT domain Mg_chelatase PF01078.21 KEG13766.1 - 0.00024 20.6 3.6 0.0088 15.4 0.1 3.8 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEG13766.1 - 0.0004 20.2 0.0 0.49 10.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KEG13766.1 - 0.00089 19.8 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 KEG13766.1 - 0.001 19.0 0.1 0.0039 17.1 0.0 2.0 2 0 0 2 2 1 1 Rad17 P-loop domain TsaE PF02367.17 KEG13766.1 - 0.0012 18.8 0.0 0.27 11.2 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KEG13766.1 - 0.0021 17.8 0.0 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KEG13766.1 - 0.0023 17.1 0.0 0.94 8.6 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) TniB PF05621.11 KEG13766.1 - 0.0027 17.1 0.0 0.42 10.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 KEG13766.1 - 0.0038 17.8 0.1 0.099 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEG13766.1 - 0.0069 16.1 0.2 0.69 9.6 0.1 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KEG13766.1 - 0.01 16.1 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KEG13766.1 - 0.013 15.4 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 KEG13766.1 - 0.015 14.4 0.0 0.062 12.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein VWA PF00092.28 KEG13766.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_19 PF13245.6 KEG13766.1 - 0.028 14.7 0.8 1 9.7 0.0 3.1 2 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KEG13766.1 - 0.03 14.0 0.0 0.27 10.8 0.0 2.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Arf PF00025.21 KEG13766.1 - 0.043 13.3 0.1 4.9 6.6 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family TrwB_AAD_bind PF10412.9 KEG13766.1 - 0.079 11.9 0.1 1.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 KEG13766.1 - 0.081 12.7 0.1 4.6 6.9 0.1 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 KEG13766.1 - 0.088 13.3 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG13766.1 - 0.12 11.9 0.4 0.76 9.4 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KEG13766.1 - 0.13 12.7 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 KEG13766.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DnaJ PF00226.31 KEG13767.1 - 2.8e-09 37.0 0.1 6.2e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain MMPL PF03176.15 KEG13767.1 - 0.15 11.0 0.7 0.2 10.6 0.7 1.2 1 0 0 1 1 1 0 MMPL family UPF0242 PF06785.11 KEG13767.1 - 0.19 11.8 12.2 0.037 14.2 5.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KEG13767.1 - 1 8.6 11.3 1.1 8.6 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2052 PF09747.9 KEG13768.1 - 0.0098 16.0 26.8 0.0098 16.0 26.8 2.8 3 0 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) GREB1 PF15782.5 KEG13768.1 - 0.3 8.1 37.0 0.52 7.4 37.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KEG13768.1 - 0.52 8.8 29.9 0.89 8.0 29.9 1.5 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 KEG13768.1 - 8 6.2 46.4 0.19 11.5 35.5 3.0 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 KEG13773.1 - 2.6e-42 145.0 0.0 2.4e-20 73.0 0.1 4.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13773.1 - 3.9e-15 55.9 0.0 3.7e-09 36.3 0.3 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.26 KEG13773.1 - 1.8e-10 41.0 0.2 3e-09 37.1 0.1 2.7 3 0 0 3 3 3 1 FHA domain Kdo PF06293.14 KEG13773.1 - 0.0099 15.3 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 KEG13773.1 - 0.047 13.9 0.0 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 FHA domain CHCH PF06747.13 KEG13774.1 - 5.9e-07 29.5 5.0 7.9e-07 29.1 5.0 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KEG13774.1 - 0.0022 18.0 4.6 0.0042 17.1 4.4 1.6 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KEG13774.1 - 0.034 14.5 1.2 0.041 14.2 1.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF2076 PF09849.9 KEG13774.1 - 1.4 8.9 9.0 1.9 8.5 9.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) UQ_con PF00179.26 KEG13775.1 - 5.3e-45 152.5 0.0 6e-45 152.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEG13775.1 - 0.00038 20.2 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KEG13775.1 - 0.014 15.3 0.2 0.029 14.2 0.2 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KEG13775.1 - 0.04 14.2 0.1 0.051 13.9 0.1 1.3 1 0 0 1 1 1 0 RWD domain DUF3670 PF12419.8 KEG13776.1 - 0.081 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 SNF2 Helicase protein MgtE PF01769.16 KEG13777.1 - 1.1e-14 54.8 0.0 3.2e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 Divalent cation transporter CesT PF05932.13 KEG13778.1 - 1.5e-10 41.2 0.0 4.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.6 KEG13778.1 - 1.9e-10 40.9 0.5 2e-08 34.4 0.8 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KEG13778.1 - 2.8e-07 30.3 1.2 2.1e-05 24.3 0.1 3.0 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 KEG13778.1 - 0.038 14.3 0.1 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 PDZ domain DUF5401 PF17380.2 KEG13778.1 - 0.85 7.6 49.6 1.3 7.1 49.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YjbH PF06082.11 KEG13778.1 - 8.3 5.1 14.5 13 4.5 14.5 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF974 PF06159.13 KEG13780.1 - 7.4e-14 52.1 0.0 2.1e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.8 KEG13781.1 - 1.5e-30 106.7 0.0 2.2e-29 102.9 0.0 2.1 1 1 0 1 1 1 1 WAHD domain of WASH complex PGP_phosphatase PF09419.10 KEG13782.1 - 0.066 12.8 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase ADK PF00406.22 KEG13783.1 - 4.8e-39 133.9 0.0 5.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEG13783.1 - 1.6e-27 96.6 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEG13783.1 - 4.2e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG13783.1 - 6.6e-05 23.1 0.1 0.00048 20.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEG13783.1 - 0.003 16.9 0.1 0.0055 16.0 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 KEG13783.1 - 0.0051 16.5 0.2 1.3 8.7 0.0 2.1 1 1 1 2 2 2 2 Thymidylate kinase Cytidylate_kin PF02224.18 KEG13783.1 - 0.062 13.0 1.5 0.21 11.3 0.2 2.3 2 1 1 3 3 3 0 Cytidylate kinase AAA_19 PF13245.6 KEG13783.1 - 0.073 13.4 0.2 0.11 12.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEG13783.1 - 0.074 12.7 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 KEG13783.1 - 0.082 13.3 0.3 0.16 12.4 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 KEG13783.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 KEG13783.1 - 0.1 12.8 0.3 0.14 12.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KEG13783.1 - 0.15 12.3 0.0 0.47 10.7 0.0 1.8 1 1 0 2 2 2 0 Hydin Adenylate kinase-like domain DZR PF12773.7 KEG13785.1 - 0.014 15.4 1.0 0.097 12.7 1.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KEG13785.1 - 0.031 14.2 1.4 0.13 12.3 0.2 2.5 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KEG13785.1 - 0.036 13.8 0.7 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KEG13785.1 - 0.059 12.8 0.1 0.22 11.0 0.1 2.1 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEG13785.1 - 0.17 12.0 2.5 0.3 11.2 0.8 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Nop14 PF04147.12 KEG13787.1 - 0.00013 20.4 17.9 0.00015 20.2 17.9 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 KEG13787.1 - 0.00022 19.8 14.6 0.00027 19.5 14.6 1.1 1 0 0 1 1 1 1 Mpp10 protein CCDC106 PF15794.5 KEG13787.1 - 0.00063 19.5 1.9 0.001 18.9 1.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 KEG13787.1 - 0.0032 16.9 17.1 0.0034 16.8 17.1 1.2 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 KEG13787.1 - 0.0033 16.9 22.2 0.0038 16.7 22.2 1.1 1 0 0 1 1 1 1 SDA1 Merozoite_SPAM PF07133.11 KEG13787.1 - 0.0042 17.1 21.0 0.029 14.4 21.0 2.0 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) CDC45 PF02724.14 KEG13787.1 - 0.0054 15.1 17.1 0.0063 14.9 17.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.7 KEG13787.1 - 0.25 11.2 9.0 0.46 10.3 9.0 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF913 PF06025.12 KEG13787.1 - 0.26 10.2 2.9 0.36 9.8 2.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KEG13787.1 - 0.72 9.0 3.4 0.83 8.8 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 KEG13787.1 - 0.77 8.4 6.0 1 8.0 6.0 1.1 1 0 0 1 1 1 0 Raftlin RNA_pol_Rpc4 PF05132.14 KEG13787.1 - 0.8 10.1 4.9 1.4 9.4 4.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KEG13787.1 - 1.3 7.7 5.3 1.6 7.4 5.3 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 KEG13787.1 - 1.5 7.5 10.0 1.9 7.2 10.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 KEG13787.1 - 2.2 7.2 17.3 3.2 6.7 17.3 1.3 1 0 0 1 1 1 0 Paf1 NPR3 PF03666.13 KEG13787.1 - 3.1 6.5 6.5 4.8 5.9 6.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3c_N PF05470.12 KEG13787.1 - 6.7 4.9 11.3 9.6 4.4 11.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Voltage_CLC PF00654.20 KEG13788.1 - 5.5e-92 308.7 29.0 5.5e-92 308.7 29.0 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KEG13788.1 - 8.2e-10 39.0 2.8 0.004 17.6 0.0 4.0 4 0 0 4 4 4 2 CBS domain TAT_signal PF10518.9 KEG13788.1 - 0.027 14.3 1.1 0.027 14.3 1.1 3.0 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Menin PF05053.13 KEG13788.1 - 1 7.6 2.6 1.5 7.1 2.6 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 KEG13788.1 - 2.6 8.7 13.6 5.9 7.5 13.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Glyco_transf_92 PF01697.27 KEG13789.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 92 PG_isomerase_N PF18353.1 KEG13790.1 - 0.081 13.3 0.3 0.17 12.3 0.3 1.6 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain TFIIA PF03153.13 KEG13790.1 - 0.13 12.2 6.3 0.17 11.9 6.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf_CCCH_4 PF18345.1 KEG13791.1 - 1.5e-16 59.8 27.5 8.5e-07 28.8 1.3 6.2 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 KEG13791.1 - 5.1e-15 54.9 35.4 0.0022 17.8 0.3 5.9 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG13791.1 - 1.1e-07 31.5 5.2 2.6e-06 27.1 0.2 5.2 5 0 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 KEG13791.1 - 1.2e-07 32.3 24.8 0.0016 19.2 0.5 5.1 1 1 4 5 5 5 4 Torus domain zf-CCHC PF00098.23 KEG13791.1 - 7.5e-07 28.9 13.2 0.0082 16.2 1.0 3.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_3 PF15663.5 KEG13791.1 - 0.00091 19.4 7.6 0.00091 19.4 7.6 3.4 2 1 2 4 4 4 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEG13791.1 - 0.0097 16.4 0.7 0.0097 16.4 0.7 6.5 6 0 0 6 6 6 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 KEG13791.1 - 0.046 13.4 0.2 0.046 13.4 0.2 4.0 4 0 0 4 4 4 0 Putative zinc-finger domain zf-CCHC_3 PF13917.6 KEG13791.1 - 0.059 13.3 0.0 0.059 13.3 0.0 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 KEG13791.1 - 0.19 11.6 12.1 1.5 8.7 3.6 3.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 KEG13791.1 - 3.9 7.3 9.7 1.7 8.4 2.3 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-UBR PF02207.20 KEG13793.1 - 1.6e-13 50.6 11.9 1.6e-13 50.6 11.9 2.9 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Ribonuc_red_sm PF00268.21 KEG13794.1 - 3.3e-114 381.1 0.6 3.9e-114 380.8 0.6 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain ACBP PF00887.19 KEG13795.1 - 2e-24 85.6 0.5 4e-24 84.6 0.5 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4486 PF14858.6 KEG13796.1 - 1.3e-08 33.9 0.1 2.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Cohesin_load PF10345.9 KEG13796.1 - 2.1e-06 26.5 0.4 1.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Cohesin loading factor GspL_C PF12693.7 KEG13796.1 - 0.00017 21.5 5.6 0.0024 17.7 0.0 3.7 2 0 0 2 2 2 1 GspL periplasmic domain TPR_2 PF07719.17 KEG13796.1 - 0.44 10.8 26.7 1.7 8.9 0.5 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG13796.1 - 3.5 7.6 11.2 2.2 8.2 0.4 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MPDZ_u10 PF16667.5 KEG13796.1 - 8.9 7.3 13.5 27 5.7 1.7 5.3 3 0 0 3 3 3 0 Unstructured region 10 on multiple PDZ protein TK PF00265.18 KEG13797.1 - 1.7e-05 24.8 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase Peptidase_S9 PF00326.21 KEG13798.1 - 7.5e-66 221.6 0.0 9e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KEG13798.1 - 4e-06 25.9 0.1 5.6e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9_N PF02897.15 KEG13799.1 - 2.7e-38 131.9 0.0 3e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4464 PF14713.6 KEG13800.1 - 2e-86 289.1 0.2 2.3e-86 289.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Pyr_redox_2 PF07992.14 KEG13802.1 - 3.1e-48 164.5 1.2 4.5e-48 164.0 1.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEG13802.1 - 1.7e-21 76.5 0.1 2.9e-18 66.2 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEG13802.1 - 1.9e-18 66.7 0.7 4.7e-18 65.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_oxidored PF12831.7 KEG13802.1 - 4.1e-08 33.0 0.6 6.8e-08 32.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEG13802.1 - 1.5e-07 31.0 5.2 6e-07 29.0 5.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEG13802.1 - 3.9e-05 22.9 1.6 0.018 14.2 0.8 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 KEG13802.1 - 3.9e-05 23.4 6.7 0.0058 16.3 0.7 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEG13802.1 - 0.00015 21.1 0.2 0.014 14.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEG13802.1 - 0.00016 20.5 8.0 0.0022 16.7 1.1 3.5 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 KEG13802.1 - 0.00035 20.7 2.6 0.14 12.4 0.9 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEG13802.1 - 0.0009 18.6 1.7 0.087 12.0 0.1 3.3 3 1 1 4 4 4 1 FAD binding domain Lycopene_cycl PF05834.12 KEG13802.1 - 0.0011 18.2 1.2 0.055 12.5 0.5 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KEG13802.1 - 0.0011 18.3 0.0 0.0045 16.4 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEG13802.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEG13802.1 - 0.0032 16.9 0.0 0.0088 15.4 0.0 1.7 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.21 KEG13802.1 - 0.0042 16.4 1.2 1.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KEG13802.1 - 0.0055 15.8 1.9 0.0055 15.8 1.9 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KEG13802.1 - 0.007 16.8 0.4 2.4 8.7 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KEG13802.1 - 0.23 11.5 1.8 0.5 10.4 0.1 2.4 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KEG13802.1 - 2.3 6.9 4.7 6.4 5.5 0.5 3.3 3 1 1 4 4 4 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KEG13802.1 - 4.1 7.4 5.8 2.6 8.0 0.3 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding Bac_surface_Ag PF01103.23 KEG13803.1 - 8.7e-20 71.5 0.9 1.1e-19 71.1 0.9 1.3 1 0 0 1 1 1 1 Surface antigen Folliculin PF11704.8 KEG13804.1 - 1.7e-10 41.1 0.0 4.1e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 KEG13804.1 - 1.4e-07 31.5 1.5 3.8e-07 30.1 0.5 2.0 2 0 0 2 2 2 1 Folliculin C-terminal domain Adeno_E3_14_5 PF04834.12 KEG13805.1 - 0.11 13.1 0.3 0.34 11.5 0.3 1.9 1 1 0 1 1 1 0 Early E3 14.5 kDa protein TPR_1 PF00515.28 KEG13806.1 - 4.7e-10 38.9 0.5 0.00094 18.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG13806.1 - 4.9e-10 38.7 4.8 0.0004 20.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG13806.1 - 9.3e-08 32.0 0.4 0.0027 18.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG13806.1 - 4.8e-07 29.4 0.3 0.0013 18.3 0.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 KEG13806.1 - 2.6e-05 24.1 0.2 0.71 10.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEG13806.1 - 0.00025 20.3 0.6 0.081 12.1 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13806.1 - 0.00029 21.4 7.6 0.024 15.4 1.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG13806.1 - 0.00063 20.3 2.4 0.00063 20.3 2.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG13806.1 - 0.0024 18.0 2.7 0.007 16.5 2.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG13806.1 - 0.0088 16.5 7.9 0.068 13.7 0.7 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KEG13806.1 - 0.0097 16.4 4.0 0.09 13.2 4.0 2.4 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 KEG13806.1 - 0.24 11.7 6.2 0.27 11.5 1.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG13806.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG13806.1 - 2 8.4 10.8 0.37 10.7 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S8 PF00410.19 KEG13807.1 - 6.2e-21 74.7 0.0 7.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 PTCB-BRCT PF12738.7 KEG13808.1 - 9e-16 57.6 0.1 7.6e-11 41.8 0.0 4.5 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 KEG13808.1 - 2.5e-15 56.6 0.0 3.4e-05 24.1 0.0 5.6 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KEG13808.1 - 1e-09 38.2 0.0 4e-08 33.0 0.0 3.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KEG13808.1 - 3.5e-05 23.8 0.2 0.29 11.2 0.0 3.8 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEG13808.1 - 0.11 12.9 0.0 8.1 6.9 0.0 3.8 5 0 0 5 5 5 0 BRCT domain, a BRCA1 C-terminus domain Diphthamide_syn PF01866.17 KEG13809.1 - 2e-112 375.6 0.0 2.4e-112 375.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Flagellar_rod PF05149.12 KEG13810.1 - 7.2e-107 357.1 32.8 7.2e-107 357.1 32.8 3.1 2 1 1 3 3 3 2 Paraflagellar rod protein Pox_A_type_inc PF04508.12 KEG13810.1 - 0.56 10.1 6.5 1.3 9.0 0.1 3.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MutS_V PF00488.21 KEG13811.1 - 2.6e-20 73.3 0.6 5e-20 72.3 0.6 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEG13811.1 - 8.5e-18 65.3 0.0 1.5e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain III AAA_30 PF13604.6 KEG13811.1 - 3.1e-06 27.0 0.9 8e-06 25.7 0.9 1.6 1 1 0 1 1 1 1 AAA domain MutS_IV PF05190.18 KEG13811.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV AAA_19 PF13245.6 KEG13811.1 - 0.0063 16.9 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG13811.1 - 0.0092 16.3 0.0 0.032 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KEG13811.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Viral_helicase1 PF01443.18 KEG13811.1 - 0.014 15.2 0.1 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KEG13811.1 - 0.015 15.1 0.0 0.07 12.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF463 PF04317.12 KEG13811.1 - 0.058 12.3 0.3 0.11 11.4 0.3 1.4 1 1 0 1 1 1 0 YcjX-like family, DUF463 AAA_21 PF13304.6 KEG13811.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MORN PF02493.20 KEG13812.1 - 5.8e-68 220.9 110.5 6e-05 22.7 1.2 23.4 23 1 0 23 23 23 19 MORN repeat PATR PF12951.7 KEG13812.1 - 0.17 12.0 11.7 0.17 12.0 1.2 4.0 3 0 0 3 3 3 0 Passenger-associated-transport-repeat 4HBT PF03061.22 KEG13813.1 - 1.5e-13 50.9 3.2 5.3e-08 33.1 2.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 KEG13813.1 - 2e-05 24.1 0.3 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 MaoC like domain 4HBT_2 PF13279.6 KEG13813.1 - 0.00019 21.9 0.0 0.0018 18.8 0.0 2.1 1 1 1 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 KEG13814.1 - 1.2e-12 48.0 3.8 9.2e-07 29.1 0.4 2.5 2 0 0 2 2 2 2 Thioesterase superfamily YPEB PF14620.6 KEG13815.1 - 0.087 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 YpeB sporulation Golgin_A5 PF09787.9 KEG13815.1 - 0.092 12.2 3.9 3.5 7.0 3.5 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DMPK_coil PF08826.10 KEG13815.1 - 0.27 11.4 8.2 0.074 13.2 3.2 2.4 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF1192 PF06698.11 KEG13815.1 - 0.42 10.7 3.3 21 5.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Thioredoxin PF00085.20 KEG13816.1 - 6.9e-13 48.5 0.0 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KEG13816.1 - 2.3e-07 31.2 0.0 7.6e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEG13816.1 - 0.00078 19.7 0.0 0.0047 17.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KEG13816.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 KEG13816.1 - 0.073 13.3 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin Redoxin PF08534.10 KEG13816.1 - 0.15 11.8 0.1 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Redoxin Thioredoxin_7 PF13899.6 KEG13816.1 - 0.18 12.0 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Peptidase_S8 PF00082.22 KEG13817.1 - 6.8e-33 114.2 0.0 1.1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Subtilase family CUB PF00431.20 KEG13817.1 - 2.3e-09 37.5 0.0 8.7e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 CUB domain ABC_tran PF00005.27 KEG13818.1 - 7.7e-28 97.7 0.0 1.2e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG13818.1 - 1.4e-07 31.7 1.3 4e-05 23.6 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG13818.1 - 0.0015 18.1 0.0 0.084 12.3 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEG13818.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEG13818.1 - 0.039 13.7 0.1 0.075 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEG13818.1 - 0.056 13.8 0.1 0.085 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KEG13818.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KEG13818.1 - 0.21 11.5 0.6 0.8 9.6 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KEG13818.1 - 0.31 11.5 1.0 0.48 10.9 0.2 1.7 2 0 0 2 2 2 0 AAA domain RINGv PF12906.7 KEG13819.1 - 3e-10 40.1 10.2 7.8e-10 38.7 10.2 1.8 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KEG13819.1 - 0.00081 19.7 7.5 0.00081 19.7 7.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KEG13819.1 - 0.82 10.0 5.2 4.1 7.8 5.2 2.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 KEG13819.1 - 1.1 9.6 5.1 0.7 10.3 2.7 2.0 2 0 0 2 2 2 0 RING-like domain zf-C3HC4 PF00097.25 KEG13819.1 - 4.9 7.1 6.2 15 5.6 6.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane_3 PF12698.7 KEG13820.1 - 5.4e-41 140.9 23.0 1.8e-40 139.1 23.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KEG13820.1 - 7.4e-24 84.8 0.0 1.4e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG13820.1 - 4.3e-09 36.6 0.0 1e-06 28.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KEG13820.1 - 0.017 14.4 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KEG13820.1 - 0.09 12.4 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TatD_DNase PF01026.21 KEG13821.1 - 5e-43 147.3 0.0 6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase GCOM2 PF15328.6 KEG13822.1 - 4.2e-05 24.0 1.6 0.00013 22.4 1.6 1.7 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 4HBT_3 PF13622.6 KEG13823.1 - 3.6e-44 151.9 0.1 5.2e-44 151.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KEG13823.1 - 1.7e-21 76.4 0.0 3.1e-17 62.7 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase Arm PF00514.23 KEG13825.1 - 5.8e-08 32.5 4.7 0.25 11.4 0.0 5.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KEG13825.1 - 6.2e-06 26.5 17.2 0.059 13.8 1.8 4.8 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.22 KEG13825.1 - 0.0037 17.4 14.0 1.8 9.1 0.1 6.1 7 0 0 7 7 7 2 HEAT repeat Zea_mays_MuDR PF05928.11 KEG13825.1 - 0.31 10.6 2.8 0.43 10.2 1.4 1.9 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) HEAT_EZ PF13513.6 KEG13825.1 - 0.37 11.3 15.1 8.2 7.0 0.0 5.5 6 0 0 6 6 6 0 HEAT-like repeat PapD-like PF14874.6 KEG13827.1 - 7.1e-34 116.0 0.2 1.4e-33 115.1 0.2 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like UPF0175 PF03683.13 KEG13827.1 - 0.017 14.8 1.9 0.044 13.5 1.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) CDC45 PF02724.14 KEG13827.1 - 0.052 11.9 2.4 0.14 10.5 2.4 1.6 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KEG13827.1 - 0.57 9.4 4.5 1.3 8.3 4.5 1.5 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KEG13827.1 - 2 8.1 6.4 4.6 6.9 3.2 2.7 2 0 0 2 2 2 0 FAM176 family Nodulin-like PF06813.13 KEG13828.1 - 1.2e-14 54.4 12.6 1.2e-14 54.4 12.6 2.5 2 1 0 2 2 2 2 Nodulin-like MFS_1 PF07690.16 KEG13828.1 - 3.9e-11 42.5 39.1 1.9e-06 27.1 8.3 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily Ras PF00071.22 KEG13829.1 - 5.1e-50 169.2 0.0 6.1e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG13829.1 - 2.2e-19 69.8 0.0 3.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG13829.1 - 7.5e-06 25.5 0.0 9.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEG13829.1 - 0.00029 20.4 0.1 0.00059 19.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG13829.1 - 0.0041 17.2 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Corazonin PF17308.2 KEG13829.1 - 0.02 15.3 0.0 0.045 14.1 0.0 1.5 2 0 0 2 2 2 0 Pro-corazonin RsgA_GTPase PF03193.16 KEG13829.1 - 0.027 14.4 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF3568 PF12092.8 KEG13829.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF834 PF05754.14 KEG13832.1 - 0.00024 21.0 1.6 0.00045 20.2 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF834) GAS PF13851.6 KEG13833.1 - 0.0083 15.5 3.2 0.011 15.1 3.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 KEG13833.1 - 0.015 15.6 0.6 0.023 15.0 0.6 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 KEG13833.1 - 0.018 15.2 1.9 0.018 15.2 1.9 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Nup54 PF13874.6 KEG13833.1 - 0.098 12.8 1.9 0.14 12.2 1.9 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Ribosomal_L4 PF00573.22 KEG13834.1 - 3.7e-11 43.1 0.0 1.1e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family TruD PF01142.18 KEG13835.1 - 0.00012 21.1 0.0 0.0019 17.1 0.0 2.5 3 0 0 3 3 3 1 tRNA pseudouridine synthase D (TruD) SH3_9 PF14604.6 KEG13837.1 - 2.9e-11 43.0 0.1 7.9e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KEG13837.1 - 5.4e-09 35.6 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEG13837.1 - 7.2e-08 31.9 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NifQ PF04891.12 KEG13837.1 - 0.16 12.3 3.1 0.18 12.1 0.7 2.3 1 1 0 2 2 2 0 NifQ DUF2959 PF11172.8 KEG13837.1 - 0.25 11.5 9.5 8.6 6.4 6.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) PI-PLC-X PF00388.19 KEG13838.1 - 7.6e-63 210.4 0.0 1.2e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEG13838.1 - 3e-34 117.8 0.0 6.6e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KEG13838.1 - 4.1e-11 43.1 0.0 8.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KEG13838.1 - 9.5e-05 22.8 0.0 0.00052 20.4 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG13838.1 - 0.00059 19.2 0.1 0.013 15.0 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.11 KEG13838.1 - 0.0017 18.8 0.0 0.0047 17.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 KEG13838.1 - 0.0045 16.8 0.6 0.49 10.5 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KEG13838.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 EF hand SfLAP PF11139.8 KEG13839.1 - 0.08 12.4 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF2339 PF10101.9 KEG13839.1 - 0.12 10.9 0.1 0.13 10.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Erv26 PF04148.13 KEG13839.1 - 0.14 12.0 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 WD40 PF00400.32 KEG13841.1 - 0.00018 22.2 12.8 0.2 12.6 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13841.1 - 0.15 12.4 0.2 32 4.9 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF667 PF05018.13 KEG13845.1 - 8e-06 25.7 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF667) LSM PF01423.22 KEG13846.1 - 7.2e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 LSM domain Mating_C PF12737.7 KEG13846.1 - 0.042 13.1 0.4 0.43 9.7 0.2 2.1 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 SM-ATX PF14438.6 KEG13846.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Ataxin 2 SM domain zf-C3HC4_3 PF13920.6 KEG13847.1 - 1.2e-09 37.8 10.4 1.2e-09 37.8 10.4 4.3 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG13847.1 - 3.9e-09 36.2 12.2 3.9e-09 36.2 12.2 2.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG13847.1 - 1.2e-06 28.4 13.4 1.2e-06 28.4 13.4 2.9 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEG13847.1 - 2.1e-06 27.5 11.0 2.1e-06 27.5 11.0 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEG13847.1 - 7.8e-06 26.1 12.3 7.8e-06 26.1 12.3 3.7 4 0 0 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 KEG13847.1 - 4.6e-05 23.3 13.3 4.6e-05 23.3 13.3 3.8 5 1 0 5 5 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KEG13847.1 - 6.1e-05 23.1 12.7 6.1e-05 23.1 12.7 3.2 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KEG13847.1 - 0.00025 20.8 11.2 0.00025 20.8 11.2 3.8 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KEG13847.1 - 0.00049 19.9 7.4 0.0019 18.0 7.4 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.15 KEG13847.1 - 0.014 15.6 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 U-box domain zf-RING_10 PF16685.5 KEG13847.1 - 0.031 14.4 9.0 0.031 14.4 9.0 3.0 3 0 0 3 3 2 0 zinc RING finger of MSL2 Histone PF00125.24 KEG13848.1 - 3.5e-10 40.3 0.0 5.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KEG13848.1 - 9.9e-09 34.8 0.1 2.5e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A 2Fe-2S_thioredx PF01257.19 KEG13849.1 - 3.2e-47 160.0 0.0 4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RCC1 PF00415.18 KEG13851.1 - 2e-71 236.5 25.7 2.8e-15 56.7 0.4 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEG13851.1 - 3.1e-31 106.5 39.5 8.9e-11 41.3 3.2 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.22 KEG13851.1 - 3.1e-09 37.1 0.0 4.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4213 PF13938.6 KEG13851.1 - 0.0014 18.8 3.2 8.8 6.6 0.0 4.3 4 0 0 4 4 4 2 Putative heavy-metal chelation Pkinase PF00069.25 KEG13852.1 - 1.1e-64 218.3 0.0 1.7e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13852.1 - 1.2e-34 119.8 0.0 1.9e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KEG13852.1 - 2.8e-33 113.9 0.1 1.1e-15 57.5 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KEG13852.1 - 3.9e-06 26.4 0.0 2.2e-05 24.0 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEG13852.1 - 0.00012 21.0 0.1 0.00012 21.0 0.1 2.4 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KEG13852.1 - 0.027 14.4 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Spt20 PF12090.8 KEG13852.1 - 0.3 10.7 10.6 0.61 9.7 10.6 1.4 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 KEG13853.1 - 7.8e-26 89.8 20.9 8e-07 29.7 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13853.1 - 7e-08 32.7 0.4 0.3 11.4 0.2 5.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG13853.1 - 2.4e-07 30.0 1.4 0.13 11.2 0.0 3.9 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEG13853.1 - 0.0012 17.6 2.2 0.015 14.0 0.0 3.1 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Frtz PF11768.8 KEG13853.1 - 0.0043 15.4 0.3 0.045 12.1 0.1 2.0 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz NTNH_C PF08470.10 KEG13853.1 - 0.05 13.5 0.0 2.6 7.9 0.0 2.3 1 1 1 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal PD40 PF07676.12 KEG13853.1 - 0.067 13.2 0.1 3.4 7.7 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ROF PF07073.12 KEG13853.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) nos_propeller PF18764.1 KEG13853.1 - 0.25 11.3 1.0 4.5 7.3 0.1 3.0 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Kinesin PF00225.23 KEG13854.1 - 4.4e-79 265.8 0.0 6.7e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG13854.1 - 4.2e-17 62.5 0.0 9.2e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KEG13854.1 - 0.044 14.2 2.2 0.085 13.2 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain FAP206 PF12018.8 KEG13855.1 - 6.2e-15 55.4 0.0 2.3e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function CDT1_C PF16679.5 KEG13855.1 - 0.054 13.9 1.1 0.73 10.3 0.1 2.5 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain GP3_package PF16677.5 KEG13855.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 DNA-packaging protein gp3 Pyr_redox_2 PF07992.14 KEG13856.1 - 1.1e-14 54.4 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEG13856.1 - 5.9e-09 35.8 0.5 6.8e-09 35.6 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEG13856.1 - 3.3e-06 26.1 0.1 2.7e-05 23.1 0.1 2.0 2 1 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KEG13856.1 - 4.9e-06 25.9 0.2 5.6e-06 25.7 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEG13856.1 - 6.3e-06 26.0 1.1 7.1e-05 22.6 0.6 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KEG13856.1 - 1.3e-05 24.4 0.1 2.5e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KEG13856.1 - 9.4e-05 22.6 0.3 0.00096 19.3 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEG13856.1 - 0.00054 19.3 1.3 0.0034 16.7 0.5 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEG13856.1 - 0.0037 16.4 2.0 0.004 16.3 0.6 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEG13856.1 - 0.0045 17.0 0.4 0.021 14.8 0.1 2.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KEG13856.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KEG13856.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KEG13856.1 - 0.028 13.7 1.2 0.15 11.3 0.2 2.3 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.6 KEG13856.1 - 0.056 12.6 0.1 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KEG13856.1 - 0.1 13.2 0.3 0.44 11.1 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEG13857.1 - 1.2e-39 136.3 0.1 2e-39 135.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEG13857.1 - 5e-17 62.2 0.0 1.6e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEG13857.1 - 4.7e-13 49.5 0.6 5.6e-11 42.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEG13857.1 - 3.8e-08 33.1 0.1 3.8e-08 33.1 0.1 2.2 3 0 0 3 3 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEG13857.1 - 2.7e-07 29.7 0.8 0.00042 19.1 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 KEG13857.1 - 5.6e-07 29.7 1.3 0.023 14.9 0.2 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEG13857.1 - 1.1e-05 24.8 1.1 0.12 11.6 0.5 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEG13857.1 - 0.00012 21.4 0.1 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KEG13857.1 - 0.00028 20.1 3.9 0.041 12.9 1.0 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEG13857.1 - 0.0014 17.7 4.5 0.0033 16.6 0.5 2.8 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEG13857.1 - 0.0015 17.9 1.2 0.62 9.3 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KEG13857.1 - 0.0021 17.7 5.2 0.066 12.8 0.7 3.0 2 2 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEG13857.1 - 0.0022 17.3 0.3 0.012 14.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KEG13857.1 - 0.004 16.3 0.0 0.021 13.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEG13857.1 - 0.01 15.1 1.7 0.41 9.8 0.1 3.1 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 KEG13857.1 - 0.011 15.7 0.9 0.031 14.2 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KEG13857.1 - 0.074 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family CCDC24 PF15669.5 KEG13857.1 - 1.5 8.6 3.9 2.9 7.7 3.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 KEG13857.1 - 4 7.0 12.4 6.6 6.3 12.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3682 PF12446.8 KEG13858.1 - 2.1 8.8 7.3 1.3 9.5 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) TMEM52 PF14979.6 KEG13860.1 - 0.0021 18.0 0.3 0.0031 17.4 0.3 1.2 1 0 0 1 1 1 1 Transmembrane 52 Herpes_gE PF02480.16 KEG13860.1 - 0.0032 16.3 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KEG13860.1 - 0.021 15.7 0.1 0.027 15.3 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR19-TM PF15176.6 KEG13860.1 - 0.031 14.3 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SIT PF15330.6 KEG13860.1 - 0.039 14.4 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LYRIC PF15686.5 KEG13860.1 - 0.1 12.1 0.8 0.14 11.7 0.8 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family PRIMA1 PF16101.5 KEG13860.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MLANA PF14991.6 KEG13860.1 - 0.15 12.4 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A PepSY_TM PF03929.16 KEG13860.1 - 0.19 11.3 0.2 0.23 11.1 0.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region LST1 PF05083.13 KEG13860.1 - 0.73 10.2 5.7 1.3 9.4 5.7 1.5 1 1 0 1 1 1 0 LST-1 protein SelK_SelG PF10961.8 KEG13862.1 - 0.08 13.6 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Methyltransf_11 PF08241.12 KEG13866.1 - 0.027 15.1 0.0 0.062 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPR_7 PF13176.6 KEG13867.1 - 0.024 14.7 0.0 12 6.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Tma16 PF11176.8 KEG13868.1 - 2.2e-24 86.0 0.1 2.2e-24 86.0 0.1 2.0 2 0 0 2 2 2 1 Translation machinery-associated protein 16 Cas1_AcylT PF07779.12 KEG13869.1 - 1.8e-79 267.9 25.4 2.4e-79 267.5 25.4 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF3397 PF11877.8 KEG13869.1 - 0.0019 18.4 3.9 0.0019 18.4 3.9 5.2 5 2 0 6 6 6 1 Protein of unknown function (DUF3397) DUF3098 PF11297.8 KEG13869.1 - 0.25 11.0 2.1 6.2 6.5 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) DUF5317 PF17248.2 KEG13869.1 - 5.7 6.9 12.1 33 4.5 0.5 3.9 3 0 0 3 3 3 0 Family of unknown function (DUF5317) MTHFR PF02219.17 KEG13870.1 - 6.5e-97 324.3 0.0 7.5e-97 324.1 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RabGAP-TBC PF00566.18 KEG13871.1 - 4.9e-14 52.5 0.5 8.6e-14 51.7 0.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 KEG13872.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF3572 PF12096.8 KEG13872.1 - 0.18 12.0 0.1 1.3 9.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3572) DUF1126 PF06565.12 KEG13873.1 - 8.9e-62 205.5 0.6 6.4e-21 74.2 0.1 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 KEG13873.1 - 0.0024 18.3 0.4 0.21 12.1 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG13873.1 - 0.048 13.2 0.0 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 KEG13874.1 - 2e-58 197.8 0.0 2.5e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13874.1 - 1.9e-33 115.8 0.0 2.6e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG13874.1 - 1.5e-13 50.8 0.0 1.1e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEG13874.1 - 4e-05 23.1 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 KEG13874.1 - 5.8e-05 23.0 1.1 0.00011 22.2 1.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KEG13874.1 - 0.00033 20.3 1.0 0.00092 18.9 1.0 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KEG13874.1 - 0.0017 19.1 0.1 0.0034 18.1 0.1 1.5 1 0 0 1 1 1 1 zinc-ribbon family DUF2116 PF09889.9 KEG13874.1 - 0.039 13.9 1.4 0.18 11.8 0.7 2.0 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pkinase_fungal PF17667.1 KEG13874.1 - 0.041 12.7 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zf-dskA_traR PF01258.17 KEG13874.1 - 0.092 12.7 2.6 1.4 9.0 0.4 2.5 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-ribbon_3 PF13248.6 KEG13874.1 - 0.12 11.8 1.6 0.29 10.6 1.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain ABC2_membrane PF01061.24 KEG13875.1 - 5.9e-35 120.6 15.8 5.9e-35 120.6 15.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KEG13875.1 - 7.4e-20 71.9 0.0 1.3e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEG13875.1 - 0.00025 21.0 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEG13875.1 - 0.00066 19.2 0.0 0.011 15.2 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KEG13875.1 - 0.0012 19.0 0.0 0.003 17.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG13875.1 - 0.0019 18.2 0.1 0.0057 16.6 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 KEG13875.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEG13875.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEG13875.1 - 0.01 16.2 0.1 0.02 15.3 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEG13875.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEG13875.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEG13875.1 - 0.059 13.9 0.0 0.15 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain PRK PF00485.18 KEG13875.1 - 0.063 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 KEG13875.1 - 0.072 13.0 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KEG13875.1 - 0.093 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 KEG13875.1 - 0.096 12.4 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEG13875.1 - 0.11 12.8 0.2 0.3 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KEG13875.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 KEG13875.1 - 0.15 12.3 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KEG13875.1 - 0.16 11.3 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ribosomal_S8e PF01201.22 KEG13876.1 - 1.7e-46 157.8 6.0 2.8e-46 157.1 6.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.8 KEG13876.1 - 0.028 14.3 0.2 0.18 11.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) CCDC-167 PF15188.6 KEG13876.1 - 0.33 11.3 3.5 0.7 10.3 3.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Mpp10 PF04006.12 KEG13878.1 - 3.3e-13 49.0 37.1 9.4e-13 47.5 37.1 2.2 1 1 0 1 1 1 1 Mpp10 protein HSP90 PF00183.18 KEG13879.1 - 8.8e-160 533.0 11.1 4.6e-156 520.7 5.4 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KEG13879.1 - 8.9e-08 32.6 0.0 1.5e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEG13879.1 - 2.4e-07 30.6 0.0 5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase U-box PF04564.15 KEG13881.1 - 8.7e-13 48.3 0.0 3.3e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KEG13881.1 - 8.5e-06 25.5 0.0 3.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KEG13881.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEG13881.1 - 0.052 13.8 0.1 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEG13881.1 - 0.12 12.8 0.0 0.6 10.5 0.0 2.3 1 0 0 1 1 1 0 Ring finger domain zf-NOSIP PF15906.5 KEG13881.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Band_7 PF01145.25 KEG13882.1 - 5.9e-22 78.5 0.0 7.9e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family 3HBOH PF10605.9 KEG13882.1 - 0.11 10.7 0.2 0.33 9.1 0.1 1.7 2 0 0 2 2 2 0 3HB-oligomer hydrolase (3HBOH) SPX PF03105.19 KEG13883.1 - 0.052 13.5 4.0 0.089 12.7 4.1 1.4 1 1 0 1 1 1 0 SPX domain Elongin_A PF06881.11 KEG13884.1 - 0.094 13.3 0.4 0.18 12.3 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Baculo_PEP_C PF04513.12 KEG13886.1 - 0.0041 17.2 0.0 0.0052 16.8 0.0 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SEO_N PF14576.6 KEG13886.1 - 0.12 11.5 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus RE_AccI PF09545.10 KEG13887.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease EBV-NA3 PF05009.12 KEG13887.1 - 7.7 6.0 8.5 2.4 7.6 4.0 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Caldesmon PF02029.15 KEG13888.1 - 0.0022 16.8 33.4 0.0029 16.5 33.4 1.1 1 0 0 1 1 1 1 Caldesmon Nop14 PF04147.12 KEG13888.1 - 0.073 11.3 41.8 0.097 10.9 41.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KEG13888.1 - 0.47 9.7 41.4 0.67 9.2 41.5 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 KEG13888.1 - 0.9 8.6 18.6 1.2 8.1 18.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HMG_box PF00505.19 KEG13890.1 - 1.4e-40 137.5 12.0 6.6e-22 77.7 2.8 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KEG13890.1 - 3e-25 88.6 12.7 6.9e-13 49.0 3.0 2.6 2 0 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 KEG13890.1 - 7.6e-07 29.4 10.6 0.0024 18.1 0.6 2.3 1 1 1 2 2 2 2 Protamine and protamine like DEK_C PF08766.11 KEG13890.1 - 1.6e-05 24.7 0.0 1.6e-05 24.7 0.0 2.4 3 0 0 3 3 3 1 DEK C terminal domain YABBY PF04690.13 KEG13890.1 - 0.0031 18.1 1.7 0.0031 18.1 1.7 1.8 1 1 1 2 2 2 1 YABBY protein DUF4019 PF13211.6 KEG13890.1 - 0.0046 17.3 2.6 0.0061 16.9 0.6 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF4019) HMG_box_5 PF14887.6 KEG13890.1 - 2 8.5 15.2 0.45 10.5 1.5 3.4 3 1 0 3 3 3 0 HMG (high mobility group) box 5 RRM_1 PF00076.22 KEG13892.1 - 1.4e-07 31.2 0.0 3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG13892.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KEG13892.1 - 0.055 13.1 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Choline_transpo PF04515.12 KEG13893.1 - 1.8e-59 201.6 27.0 1.8e-59 201.6 27.0 2.4 3 0 0 3 3 3 1 Plasma-membrane choline transporter UL45 PF05473.12 KEG13893.1 - 0.081 12.6 3.5 0.22 11.1 3.5 1.8 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Mobilization_B PF17511.2 KEG13893.1 - 0.24 11.8 7.8 0.043 14.2 3.0 2.2 2 0 0 2 2 2 0 Mobilization protein B Cyt-b5 PF00173.28 KEG13894.1 - 3.7e-11 43.0 0.1 5.2e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_19 PF14559.6 KEG13895.1 - 0.0045 17.5 3.3 2.6 8.6 0.2 3.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG13895.1 - 0.017 15.9 5.8 2.3 9.2 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG13895.1 - 0.066 13.5 8.4 0.99 9.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Arf PF00025.21 KEG13896.1 - 6.1e-66 221.2 0.0 6.8e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEG13896.1 - 8.7e-16 57.9 0.0 1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KEG13896.1 - 6.3e-15 55.4 0.0 8.6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KEG13896.1 - 8.6e-14 51.4 0.1 2.6e-10 40.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KEG13896.1 - 1.2e-13 51.0 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEG13896.1 - 3.9e-12 46.0 0.0 4.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG13896.1 - 7.6e-09 35.7 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG13896.1 - 0.00019 21.1 0.0 0.00059 19.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KEG13896.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 KEG13896.1 - 0.015 14.9 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KEG13896.1 - 0.018 15.0 0.0 3.9 7.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 KEG13896.1 - 0.031 13.3 0.1 0.24 10.4 0.1 2.1 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KEG13896.1 - 0.041 14.3 0.0 0.095 13.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG13896.1 - 0.064 13.6 0.2 0.23 11.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Vmethyltransf PF01660.17 KEG13896.1 - 0.18 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase PhyH PF05721.13 KEG13897.1 - 2.3e-06 28.0 0.0 3.8e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Oxidored_FMN PF00724.20 KEG13898.1 - 2.8e-56 191.2 0.0 3.8e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KEG13898.1 - 7.6e-24 84.4 0.0 1.5e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEG13898.1 - 2.9e-11 43.6 1.2 2.5e-07 30.6 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEG13898.1 - 1.2e-09 38.2 0.4 1.5e-08 34.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEG13898.1 - 3.2e-09 37.2 1.3 8.2e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG13898.1 - 1.4e-08 34.4 0.1 0.0025 17.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEG13898.1 - 1.4e-06 28.0 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KEG13898.1 - 3.3e-06 26.5 0.0 0.0016 17.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KEG13898.1 - 6.3e-06 25.1 1.1 1.4e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KEG13898.1 - 5.3e-05 23.3 0.3 0.0049 16.9 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEG13898.1 - 5.9e-05 22.3 0.3 0.00015 20.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEG13898.1 - 0.00015 21.1 0.3 0.0051 16.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KEG13898.1 - 0.0004 19.7 0.2 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KEG13898.1 - 0.00049 20.5 0.1 0.047 14.1 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.17 KEG13898.1 - 0.00088 19.8 0.8 2.4 8.8 0.0 3.1 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KEG13898.1 - 0.0023 18.2 0.1 0.13 12.5 0.0 2.8 2 1 1 3 3 3 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KEG13898.1 - 0.0027 17.4 0.1 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KEG13898.1 - 0.0036 17.3 0.0 0.07 13.1 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 KEG13898.1 - 0.0041 16.3 0.1 0.0041 16.3 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 KEG13898.1 - 0.011 15.7 0.7 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KEG13898.1 - 0.023 13.2 0.0 0.26 9.7 0.0 2.2 1 1 1 2 2 2 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.24 KEG13898.1 - 0.055 12.7 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KEG13898.1 - 0.09 11.6 1.0 0.27 10.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Cnd1 PF12717.7 KEG13899.1 - 2.3e-22 79.8 2.7 1.6e-17 64.1 0.0 4.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEG13899.1 - 3.2e-09 36.3 6.1 1 9.8 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat Cnd1_N PF12922.7 KEG13899.1 - 1.4e-06 28.3 0.0 5.7e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 KEG13899.1 - 5.6e-05 21.9 9.2 0.063 11.8 0.4 4.9 5 1 1 6 6 6 3 Adaptin N terminal region HEAT_EZ PF13513.6 KEG13899.1 - 0.0066 16.9 0.0 3.3 8.3 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.7 KEG13899.1 - 0.008 15.4 3.7 0.047 12.9 0.4 3.3 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 KEG13899.1 - 0.12 12.5 0.4 29 4.8 0.0 3.7 3 0 0 3 3 3 0 V-ATPase subunit H Pkinase PF00069.25 KEG13900.1 - 1.5e-58 198.3 0.0 2.7e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13900.1 - 3.6e-28 98.5 0.0 3e-27 95.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 KEG13900.1 - 1.6e-21 76.2 10.1 3e-21 75.3 10.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_fungal PF17667.1 KEG13900.1 - 0.00015 20.7 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG13900.1 - 0.0017 18.3 0.0 0.0054 16.7 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG13900.1 - 0.013 14.9 0.0 0.03 13.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like zf_C2HC_14 PF18574.1 KEG13900.1 - 0.1 12.4 2.7 0.24 11.2 2.7 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain FYVE_2 PF02318.16 KEG13900.1 - 0.27 11.5 6.1 0.24 11.6 4.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 KEG13900.1 - 1.1 9.3 9.5 2e+02 2.1 9.5 2.7 1 1 0 1 1 1 0 Double zinc ribbon CorA PF01544.18 KEG13902.1 - 6.7e-20 71.6 0.0 9.3e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein VCH_CASS14 PF18315.1 KEG13902.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Presenilin PF01080.17 KEG13903.1 - 2.2e-84 283.5 28.1 9.6e-63 212.3 11.8 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.12 KEG13904.1 - 1.5e-16 60.4 0.0 7.7e-16 58.2 0.0 2.1 1 1 1 2 2 2 1 Wyosine base formation Radical_SAM PF04055.21 KEG13904.1 - 5.6e-13 49.6 0.0 1.6e-12 48.2 0.0 1.7 2 1 0 2 2 2 1 Radical SAM superfamily Sld5 PF05916.11 KEG13905.1 - 0.00092 19.6 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein HMG_box_2 PF09011.10 KEG13907.1 - 2.2e-05 25.0 0.2 0.00048 20.7 0.1 2.4 2 0 0 2 2 2 1 HMG-box domain PDEase_I PF00233.19 KEG13908.1 - 5.7e-74 248.8 0.1 2.5e-73 246.7 0.0 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KEG13908.1 - 6.9e-35 120.6 0.1 3.3e-16 60.1 0.0 3.5 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 KEG13908.1 - 4.4e-21 75.6 0.2 2.3e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 KEG13908.1 - 1.6e-08 35.0 0.0 0.00092 19.6 0.0 3.7 3 0 0 3 3 3 2 GAF domain Ribosomal_L7Ae PF01248.26 KEG13909.1 - 2.7e-25 87.9 0.0 3.2e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KEG13909.1 - 2.5e-05 24.1 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KEG13909.1 - 0.00071 19.7 0.1 0.00078 19.5 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 FlaC_arch PF05377.11 KEG13909.1 - 0.19 12.1 0.8 0.37 11.2 0.1 1.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ICE2 PF08426.10 KEG13910.1 - 0.0036 16.5 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 ICE2 DUF2681 PF10883.8 KEG13910.1 - 0.079 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF679 PF05078.12 KEG13910.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF679) GHMP_kinases_N PF00288.26 KEG13911.1 - 1.1e-12 48.0 2.5 1.1e-12 48.0 2.5 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEG13911.1 - 6e-06 26.5 0.5 3.7e-05 24.0 0.2 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal PCNA_N PF00705.18 KEG13912.1 - 4.7e-43 145.9 3.0 4.4e-42 142.8 2.3 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KEG13912.1 - 9.1e-39 132.6 0.1 5.2e-19 68.7 0.1 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KEG13912.1 - 2.2e-06 27.3 0.1 3.9e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 KEG13912.1 - 0.00012 21.3 0.3 0.002 17.3 0.2 2.2 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KEG13912.1 - 0.0015 17.7 0.2 0.006 15.7 0.3 1.9 1 1 1 2 2 2 1 Hus1-like protein tRNA-synt_1c PF00749.21 KEG13913.1 - 5.9e-103 344.1 0.1 7.6e-103 343.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEG13913.1 - 1.1e-39 136.1 0.0 1.8e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain MutS_V PF00488.21 KEG13915.1 - 1.1e-58 198.4 0.0 1.8e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEG13915.1 - 2.6e-23 83.3 1.8 2.8e-23 83.2 0.7 1.6 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KEG13915.1 - 3.1e-22 78.9 0.0 9.2e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KEG13915.1 - 4.9e-07 30.0 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV zf-RING_2 PF13639.6 KEG13916.1 - 1.9e-08 34.5 7.2 4.3e-08 33.4 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEG13916.1 - 6.8e-07 28.9 7.6 1.6e-06 27.7 7.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KEG13916.1 - 0.00016 21.6 6.3 0.00031 20.7 6.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KEG13916.1 - 0.0014 18.7 5.7 0.003 17.7 5.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KEG13916.1 - 0.0041 17.4 3.9 0.01 16.1 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 KEG13916.1 - 0.0056 16.9 2.5 0.0098 16.1 2.5 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KEG13916.1 - 0.014 15.5 2.3 0.026 14.7 2.3 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 KEG13916.1 - 0.017 15.1 6.9 0.017 15.1 6.9 1.7 2 0 0 2 2 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KEG13916.1 - 0.027 14.3 7.4 0.049 13.5 7.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEG13916.1 - 0.041 13.7 7.3 0.095 12.6 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sprouty PF05210.13 KEG13916.1 - 0.21 12.0 4.7 0.51 10.7 0.8 3.0 3 1 0 3 3 3 0 Sprouty protein (Spry) Latarcin PF10279.9 KEG13917.1 - 0.092 13.2 2.1 4.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Latarcin precursor TFIIA PF03153.13 KEG13917.1 - 3.8 7.4 9.8 4.8 7.1 9.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran_CTD PF16326.5 KEG13918.1 - 0.023 14.9 0.2 0.051 13.8 0.2 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TMEM164 PF14808.6 KEG13919.1 - 2.5e-13 50.0 7.9 3.3e-13 49.6 7.9 1.1 1 0 0 1 1 1 1 TMEM164 family TMEM208_SND2 PF05620.11 KEG13919.1 - 0.066 13.0 0.3 0.066 13.0 0.3 2.1 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 PH PF00169.29 KEG13920.1 - 0.0016 18.9 0.1 0.0024 18.3 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KEG13920.1 - 0.0041 17.5 0.4 0.0084 16.5 0.4 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-CCCH PF00642.24 KEG13922.1 - 4.6e-07 29.6 1.2 4.6e-07 29.6 1.2 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG13922.1 - 0.0012 18.5 1.3 0.0012 18.5 1.3 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG13922.1 - 0.011 15.8 1.7 0.044 13.9 1.7 2.2 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 KEG13922.1 - 0.048 14.2 1.8 0.048 14.2 1.8 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KEG13924.1 - 4.8e-08 32.7 3.9 4.8e-08 32.7 3.9 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG13924.1 - 0.0046 16.7 2.2 0.0046 16.7 2.2 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG13924.1 - 0.03 14.4 4.0 0.049 13.7 2.7 2.1 2 0 0 2 2 2 0 Zinc finger domain DEAD PF00270.29 KEG13925.1 - 2.7e-43 147.8 0.1 5.7e-43 146.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG13925.1 - 2e-28 99.0 0.1 1.7e-25 89.5 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Mito_carr PF00153.27 KEG13926.1 - 4.3e-44 148.4 0.7 3e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FMO-like PF00743.19 KEG13928.1 - 8.2e-29 100.4 0.0 1.6e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEG13928.1 - 2.9e-16 59.6 0.0 1.6e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG13928.1 - 2.1e-11 43.6 0.0 2.7e-09 36.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEG13928.1 - 1.3e-09 37.7 0.2 6.1e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KEG13928.1 - 1.7e-07 31.7 0.0 0.018 15.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG13928.1 - 8.6e-07 29.1 0.1 3.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEG13928.1 - 0.0054 15.9 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KEG13928.1 - 0.0073 16.3 0.0 0.026 14.5 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KEG13928.1 - 0.02 13.6 0.5 0.057 12.1 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 KEG13928.1 - 0.03 14.8 0.4 0.25 11.8 0.1 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 KEG13928.1 - 0.033 13.5 0.2 0.27 10.5 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase IlvN PF07991.12 KEG13928.1 - 0.036 13.7 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 KEG13928.1 - 0.19 10.9 0.4 3.7 6.7 0.4 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KEG13928.1 - 0.5 9.4 1.5 0.87 8.6 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A AAA_2 PF07724.14 KEG13929.1 - 2e-39 135.4 1.2 4.3e-31 108.3 0.2 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 KEG13929.1 - 1.9e-13 51.0 0.3 5.8e-06 26.8 0.1 3.3 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEG13929.1 - 1.5e-08 34.7 0.4 2.2e-05 24.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEG13929.1 - 5.4e-06 26.7 0.1 0.00014 22.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 KEG13929.1 - 2.6e-05 23.4 0.3 0.002 17.2 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain TniB PF05621.11 KEG13929.1 - 3.2e-05 23.4 0.2 0.0096 15.3 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 KEG13929.1 - 7e-05 23.4 0.2 0.00017 22.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain ClpB_D2-small PF10431.9 KEG13929.1 - 7.4e-05 22.7 0.1 0.00029 20.8 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 KEG13929.1 - 0.00022 21.7 0.3 0.00049 20.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KEG13929.1 - 0.00044 19.7 1.2 0.0021 17.5 0.1 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KEG13929.1 - 0.00051 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KEG13929.1 - 0.0018 18.2 0.4 0.68 9.8 0.0 2.5 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.12 KEG13929.1 - 0.0024 17.7 0.1 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 KEG13929.1 - 0.0032 17.3 1.9 0.38 10.5 0.8 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.6 KEG13929.1 - 0.0034 17.6 0.3 0.01 16.0 0.0 2.0 3 0 0 3 3 1 1 AAA domain AAA_24 PF13479.6 KEG13929.1 - 0.0043 16.8 0.8 0.3 10.8 0.8 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEG13929.1 - 0.0047 17.0 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KEG13929.1 - 0.0066 15.8 0.2 0.023 13.9 0.1 1.9 1 1 0 1 1 1 1 Zeta toxin TsaE PF02367.17 KEG13929.1 - 0.0086 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KEG13929.1 - 0.021 15.1 0.6 0.19 12.0 0.2 2.7 2 2 2 4 4 3 0 AAA domain Sigma54_activat PF00158.26 KEG13929.1 - 0.027 14.2 0.1 0.079 12.7 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KEG13929.1 - 0.029 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KEG13929.1 - 0.032 14.7 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CPT PF07931.12 KEG13929.1 - 0.033 14.0 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KEG13929.1 - 0.034 14.5 0.1 0.087 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEG13929.1 - 0.043 14.2 0.0 0.85 10.0 0.0 2.9 3 0 0 3 3 3 0 RNA helicase IstB_IS21 PF01695.17 KEG13929.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KEG13929.1 - 0.048 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KEG13929.1 - 0.11 12.5 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KEG13929.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 KEG13929.1 - 3.7 8.0 6.2 4.5 7.7 0.4 3.7 3 1 1 4 4 4 0 AAA domain OS-D PF03392.13 KEG13933.1 - 0.022 14.8 0.1 0.044 13.9 0.0 1.5 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D FSIP1 PF15554.6 KEG13936.1 - 0.016 14.3 0.3 0.016 14.3 0.3 2.0 2 0 0 2 2 2 0 FSIP1 family MerR-DNA-bind PF09278.11 KEG13936.1 - 0.034 14.7 3.5 0.49 11.0 0.0 2.7 2 0 0 2 2 2 0 MerR, DNA binding MIF4G PF02854.19 KEG13937.1 - 2.8e-22 79.4 0.0 4.3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.11 KEG13937.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 CRM1 C terminal NAD_binding_1 PF00175.21 KEG13939.1 - 4.8e-24 85.1 0.0 1.4e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG13939.1 - 5.4e-17 62.0 0.0 9e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEG13939.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Lysine_decarbox PF03641.14 KEG13940.1 - 1.2e-24 86.9 0.0 2.3e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KEG13940.1 - 3.7e-09 36.4 0.0 2.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 SLOG cluster4 family GDA1_CD39 PF01150.17 KEG13941.1 - 2e-55 188.2 0.0 1.2e-54 185.6 0.0 1.8 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Spo7 PF03907.13 KEG13941.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Spo7-like protein WD40 PF00400.32 KEG13942.1 - 7.8e-30 102.5 19.9 2.9e-05 24.7 0.0 9.4 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13942.1 - 7.2e-15 55.1 1.4 6.7e-06 26.3 0.0 6.1 4 3 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEG13942.1 - 1.5e-05 25.0 0.0 0.2 11.5 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KEG13942.1 - 0.00013 21.0 0.1 0.098 11.6 0.1 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 KEG13942.1 - 0.0044 16.4 0.3 7.2 5.8 0.0 4.3 4 2 1 5 5 5 1 CPSF A subunit region IKI3 PF04762.12 KEG13942.1 - 0.027 12.5 0.2 0.31 9.0 0.1 2.1 1 1 0 2 2 2 0 IKI3 family PD40 PF07676.12 KEG13942.1 - 0.028 14.4 0.0 15 5.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CssAB PF16831.5 KEG13942.1 - 0.12 12.8 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 Me-amine-dh_H PF06433.11 KEG13942.1 - 0.15 10.9 0.0 0.32 9.8 0.0 1.5 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) PQQ_3 PF13570.6 KEG13942.1 - 8.2 7.1 10.2 31 5.2 0.1 6.0 8 0 0 8 8 8 0 PQQ-like domain ERG2_Sigma1R PF04622.12 KEG13943.1 - 1.6e-80 269.4 0.1 1.8e-80 269.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein LRR_6 PF13516.6 KEG13944.1 - 2.2e-15 55.3 1.1 1.1 9.5 0.0 8.7 9 0 0 9 9 9 5 Leucine Rich repeat LRR_8 PF13855.6 KEG13944.1 - 1.3e-14 53.7 5.1 0.00029 20.5 0.1 5.2 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KEG13944.1 - 1.4e-12 47.5 8.1 0.00094 19.5 0.1 6.2 3 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG13944.1 - 2.7e-09 36.3 8.1 5.3 8.0 0.1 8.0 7 3 0 7 7 7 3 Leucine Rich Repeat FNIP PF05725.12 KEG13944.1 - 1.4e-07 31.5 0.0 0.69 10.1 0.0 5.9 6 0 0 6 6 6 1 FNIP Repeat DUF4841 PF16129.5 KEG13944.1 - 0.019 15.2 0.0 0.053 13.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4841) LRR_RI_capping PF18779.1 KEG13944.1 - 0.02 14.5 0.0 0.073 12.7 0.0 1.9 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat PH PF00169.29 KEG13945.1 - 2.9e-07 31.0 0.0 0.00056 20.4 0.0 2.8 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 KEG13945.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain VIT1 PF01988.19 KEG13946.1 - 2.9e-19 69.8 3.7 2.9e-19 69.8 3.7 2.1 2 0 0 2 2 2 2 VIT family Glyco_transf_24 PF18404.1 KEG13947.1 - 1.5e-133 444.2 0.9 2.4e-133 443.6 0.9 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KEG13947.1 - 3.1e-33 115.8 1.0 3.7e-32 112.3 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KEG13947.1 - 1.3e-22 80.2 1.9 9.5e-22 77.4 0.4 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KEG13947.1 - 4e-21 75.8 0.0 4.7e-20 72.3 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KEG13947.1 - 4.4e-19 68.6 0.0 9.5e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KEG13947.1 - 4.7e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 AAA_12 PF13087.6 KEG13948.1 - 1.4e-35 122.8 0.0 2.2e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEG13948.1 - 8.2e-18 65.1 0.1 2.2e-08 34.2 0.5 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEG13948.1 - 4.6e-08 33.0 0.1 0.00094 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEG13948.1 - 4.1e-06 27.2 0.0 0.093 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEG13948.1 - 0.0024 17.6 0.2 1.7 8.3 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase TrbC PF04956.13 KEG13948.1 - 0.0029 17.8 0.2 0.01 16.0 0.2 2.0 1 0 0 1 1 1 1 TrbC/VIRB2 family PhoH PF02562.16 KEG13948.1 - 0.0057 16.1 0.0 0.048 13.1 0.0 2.4 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 KEG13948.1 - 0.035 14.4 0.1 3.1 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Biotin_lipoyl_2 PF13533.6 KEG13948.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like AAA PF00004.29 KEG13948.1 - 0.058 13.8 0.2 6.9 7.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KEG13948.1 - 0.1 11.8 0.0 0.33 10.1 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-CCHC PF00098.23 KEG13948.1 - 1 9.6 6.3 2.5 8.3 6.3 1.6 1 0 0 1 1 1 0 Zinc knuckle adh_short PF00106.25 KEG13949.1 - 0.0011 18.5 0.0 0.016 14.7 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KEG13949.1 - 0.007 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Nuc_sug_transp PF04142.15 KEG13950.1 - 3.1e-28 98.9 13.3 4.6e-28 98.3 13.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter Beta_helix PF13229.6 KEG13951.1 - 2.3e-98 326.5 73.5 1.9e-17 63.5 4.8 13.7 2 2 11 14 14 14 14 Right handed beta helix region NosD PF05048.13 KEG13951.1 - 8.2e-70 234.8 34.0 3e-13 49.6 3.4 13.6 5 3 8 15 15 15 12 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KEG13951.1 - 0.00014 21.3 27.7 0.026 13.9 0.1 7.8 4 3 3 7 7 7 3 Protein of unknown function (DUF1565) Pectate_lyase_3 PF12708.7 KEG13951.1 - 0.016 15.0 48.4 1.3 8.9 0.0 11.1 5 3 5 12 12 12 0 Pectate lyase superfamily protein HEAT PF02985.22 KEG13952.1 - 0.0042 17.2 0.2 0.21 11.9 0.1 3.2 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 KEG13952.1 - 0.1 13.0 0.3 1.4 9.4 0.0 3.1 2 1 1 3 3 3 0 HEAT repeats RRN3 PF05327.11 KEG13952.1 - 0.47 8.9 4.5 1 7.8 4.5 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.32 KEG13954.1 - 0.0023 18.7 0.3 0.1 13.5 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13954.1 - 0.0049 17.1 0.1 0.15 12.3 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEG13954.1 - 0.025 14.2 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 PQQ-like domain RTT107_BRCT_5 PF16770.5 KEG13955.1 - 9.9e-06 25.4 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain FHA PF00498.26 KEG13955.1 - 0.00057 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain BRCT_2 PF16589.5 KEG13955.1 - 0.037 14.4 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF4379 PF14311.6 KEG13956.1 - 1.1e-23 83.3 29.8 2.5e-09 37.3 0.5 4.8 4 1 0 4 4 4 4 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEG13956.1 - 0.068 13.3 0.6 0.068 13.3 0.6 6.2 6 1 0 6 6 6 0 Zinc ribbon domain Adeno_PIX PF03955.14 KEG13956.1 - 4.2 7.6 7.0 0.51 10.5 2.3 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Phage_holin_Dp1 PF16938.5 KEG13957.1 - 0.35 11.1 0.8 3.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Putative phage holin Dp-1 NTF2 PF02136.20 KEG13958.1 - 9.9e-15 55.2 0.0 1.1e-14 55.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KEG13958.1 - 0.03 14.3 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Pkinase PF00069.25 KEG13959.1 - 2.7e-59 200.7 0.0 1.1e-58 198.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG13959.1 - 4.9e-33 114.5 0.1 5.2e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG13959.1 - 9.1e-06 25.8 1.0 0.047 13.6 0.5 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG13959.1 - 0.00023 20.3 0.0 0.00031 19.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KEG13959.1 - 0.0048 16.3 0.3 0.012 14.9 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEG13959.1 - 0.0082 15.5 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEG13959.1 - 0.064 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KEG13959.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.20 KEG13960.1 - 7.8e-13 48.3 0.0 9.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 KEG13961.1 - 8.1e-21 73.9 0.0 1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin ERp29_N PF07912.13 KEG13961.1 - 0.00015 21.9 0.2 0.00023 21.3 0.2 1.2 1 0 0 1 1 1 1 ERp29, N-terminal domain OST3_OST6 PF04756.13 KEG13961.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 KEG13961.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEG13961.1 - 0.024 14.9 0.0 0.74 10.2 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 KEG13961.1 - 0.025 15.0 0.5 0.63 10.5 0.5 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.11 KEG13961.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE ADH_N_assoc PF13823.6 KEG13961.1 - 0.094 12.7 0.8 0.39 10.7 0.2 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated NB-ARC PF00931.22 KEG13963.1 - 0.00034 19.9 0.0 0.00057 19.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RAP1 PF07218.11 KEG13963.1 - 0.063 11.6 0.4 0.095 11.0 0.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CTNNB1_binding PF08347.11 KEG13963.1 - 0.096 12.9 0.6 0.16 12.2 0.6 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Rrn6 PF10214.9 KEG13963.1 - 0.15 10.6 6.0 0.22 10.0 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PCO_ADO PF07847.12 KEG13965.1 - 8.7e-39 133.1 0.0 9.9e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 KEG13965.1 - 0.0007 19.3 0.0 0.083 12.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 KEG13965.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cupin Peptidase_C1 PF00112.23 KEG13966.1 - 2.1e-58 198.0 5.5 3.1e-58 197.4 5.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KEG13966.1 - 6e-13 49.0 1.1 1.2e-12 48.1 1.1 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KEG13966.1 - 0.0021 16.9 0.2 0.0092 14.8 0.1 1.8 2 0 0 2 2 2 1 Peptidase C1-like family Meiosis_expr PF15163.6 KEG13966.1 - 0.062 14.0 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 Meiosis-expressed FAD_binding_3 PF01494.19 KEG13967.1 - 1.2e-11 44.5 0.0 3.7e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KEG13967.1 - 0.0048 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase EnY2 PF10163.9 KEG13968.1 - 0.00021 21.6 0.0 0.00027 21.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2956 PF11169.8 KEG13969.1 - 0.065 13.4 2.3 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) IgaA PF07095.11 KEG13969.1 - 0.078 11.0 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Myc_N PF01056.18 KEG13970.1 - 0.015 15.2 1.7 0.028 14.3 1.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TLP-20 PF06088.11 KEG13970.1 - 0.14 12.0 0.8 0.27 11.1 0.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.12 KEG13970.1 - 0.31 9.2 8.4 0.46 8.6 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KEG13970.1 - 0.45 8.7 3.6 0.65 8.2 3.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 KEG13970.1 - 0.49 10.0 10.7 1.1 8.9 10.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RXT2_N PF08595.11 KEG13970.1 - 1.2 9.2 5.8 0.75 9.8 3.5 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KEG13970.1 - 1.6 8.4 8.4 5.1 6.7 8.4 1.8 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 KEG13970.1 - 1.6 6.7 6.8 2.2 6.3 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KEG13970.1 - 1.9 7.7 12.3 3.4 6.9 12.3 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KEG13970.1 - 7.3 7.0 7.7 27 5.2 7.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SKA2 PF16740.5 KEG13971.1 - 0.00012 21.8 1.3 0.00039 20.2 0.1 2.4 3 0 0 3 3 3 1 Spindle and kinetochore-associated protein 2 Prenyltransf PF01255.19 KEG13972.1 - 5.1e-55 186.4 0.0 3.8e-52 177.0 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase WD40 PF00400.32 KEG13973.1 - 4.9e-09 36.7 13.1 0.028 15.3 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13973.1 - 6.6e-05 23.1 0.0 0.66 10.3 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEG13973.1 - 0.015 14.9 0.0 0.052 13.1 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KEG13973.1 - 0.037 12.7 0.1 0.3 9.7 0.0 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 KEG13973.1 - 0.11 13.4 0.2 32 5.7 1.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Atg8 PF02991.16 KEG13974.1 - 4.3e-31 107.2 0.0 5.1e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEG13974.1 - 1.4e-05 25.4 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 KEG13974.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.16 KEG13975.1 - 5.2e-42 142.3 0.0 6.1e-42 142.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEG13975.1 - 2.7e-09 37.3 0.0 3.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 KEG13975.1 - 0.00031 20.4 0.0 0.00039 20.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 TIG PF01833.24 KEG13976.1 - 0.02 15.0 0.1 0.051 13.7 0.1 1.7 1 0 0 1 1 1 0 IPT/TIG domain L_HMGIC_fpl PF10242.9 KEG13976.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Amnionless PF14828.6 KEG13976.1 - 0.039 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Amnionless MLANA PF14991.6 KEG13976.1 - 0.062 13.6 0.0 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein melan-A DUF3827 PF12877.7 KEG13976.1 - 0.086 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ADH_N PF08240.12 KEG13977.1 - 3.6e-25 88.0 0.2 1.1e-24 86.4 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEG13977.1 - 1.2e-21 77.0 0.2 2.3e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEG13977.1 - 6.1e-07 29.1 1.7 4.2e-06 26.4 1.7 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEG13977.1 - 1.4e-06 29.4 0.0 2.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KEG13977.1 - 0.0013 19.0 0.4 0.0029 17.8 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain Methyltransf_25 PF13649.6 KEG13977.1 - 0.11 13.2 0.1 0.36 11.6 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KEG13977.1 - 0.12 11.6 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SET PF00856.28 KEG13978.1 - 2.8e-16 60.4 0.0 7.1e-15 55.8 0.0 3.0 3 1 0 3 3 3 1 SET domain Pox_F11 PF04943.12 KEG13979.1 - 0.011 14.9 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein FAD_binding_7 PF03441.14 KEG13981.1 - 1.2e-72 243.6 3.5 2.6e-72 242.5 3.5 1.6 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KEG13981.1 - 8.7e-32 110.4 1.6 2e-31 109.2 0.1 2.3 2 1 1 3 3 3 1 DNA photolyase Biotin_lipoyl PF00364.22 KEG13989.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 Biotin-requiring enzyme MutS_V PF00488.21 KEG13991.1 - 7e-75 251.2 0.2 1.3e-74 250.4 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEG13991.1 - 1.4e-29 103.7 2.6 1.4e-29 103.7 2.6 2.1 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 KEG13991.1 - 7.5e-20 71.1 3.1 1.6e-19 70.0 3.1 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KEG13991.1 - 0.12 12.8 1.2 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain HWE_HK PF07536.14 KEG13991.1 - 0.13 12.9 1.1 4.5 8.0 0.3 3.5 3 0 0 3 3 3 0 HWE histidine kinase TMF_TATA_bd PF12325.8 KEG13991.1 - 0.68 10.2 4.3 3.1 8.0 4.3 2.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Hydrolase_4 PF12146.8 KEG13992.1 - 1.2e-19 70.5 0.0 2.2e-15 56.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEG13992.1 - 8.1e-11 42.0 0.0 4.3e-09 36.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEG13992.1 - 4.8e-08 32.7 0.0 2.2e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEG13992.1 - 5.1e-06 26.4 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KEG13992.1 - 7.6e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEG13992.1 - 6.8e-05 23.6 0.0 0.00035 21.3 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KEG13992.1 - 0.002 17.7 0.0 0.018 14.6 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 KEG13992.1 - 0.0048 16.6 0.0 0.15 11.7 0.0 2.3 1 1 1 2 2 2 1 Putative esterase AXE1 PF05448.12 KEG13992.1 - 0.014 14.1 0.1 1.1 7.8 0.0 2.5 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 KEG13992.1 - 0.03 14.0 0.0 0.1 12.2 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KEG13992.1 - 0.032 14.2 0.0 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 KEG13992.1 - 0.096 12.4 0.0 0.37 10.6 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 KEG13992.1 - 0.12 11.7 0.1 2.4 7.4 0.0 2.4 2 1 0 2 2 2 0 Secretory lipase WD40 PF00400.32 KEG13995.1 - 6.2e-09 36.4 3.6 6.7e-05 23.6 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG13995.1 - 0.00025 21.3 0.0 1.4 9.3 0.0 3.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Fe_hyd_lg_C PF02906.14 KEG13997.1 - 2.7e-56 191.0 0.0 3.9e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain PDZ_6 PF17820.1 KEG13998.1 - 1.3e-07 31.3 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KEG13998.1 - 4.3e-06 27.0 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEG13998.1 - 0.0032 17.8 0.0 0.0079 16.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RMI1_N PF08585.12 KEG13998.1 - 0.88 9.3 2.8 0.9 9.2 1.2 1.7 1 1 1 2 2 2 0 RecQ mediated genome instability protein PDZ_2 PF13180.6 KEG13999.1 - 3.6e-05 24.0 0.0 0.00027 21.2 0.0 2.1 2 1 1 3 3 3 1 PDZ domain PDZ_6 PF17820.1 KEG13999.1 - 7.3e-05 22.5 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEG13999.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain TT_ORF2 PF02957.15 KEG14001.1 - 0.014 16.3 8.3 0.014 16.3 8.3 2.0 2 0 0 2 2 2 0 TT viral ORF2 Ank_3 PF13606.6 KEG14001.1 - 0.078 13.6 0.0 0.33 11.7 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat CTU2 PF10288.9 KEG14001.1 - 0.64 10.3 3.1 8.1 6.7 0.2 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 ANAPC15 PF15243.6 KEG14001.1 - 0.66 10.4 26.1 0.31 11.4 12.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF501 PF04417.12 KEG14001.1 - 0.71 9.7 3.5 0.22 11.3 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) MCU PF04678.13 KEG14001.1 - 1.6 8.8 7.0 2.1 8.4 1.7 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter BUD22 PF09073.10 KEG14001.1 - 3.6 6.8 20.3 4.2 6.6 13.0 2.0 2 0 0 2 2 2 0 BUD22 TBCA PF02970.16 KEG14002.1 - 0.028 14.7 2.6 0.085 13.2 2.6 1.8 1 0 0 1 1 1 0 Tubulin binding cofactor A Plasmid_stab_B PF10784.9 KEG14002.1 - 0.13 12.1 0.6 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 Plasmid stability protein DUF2120 PF09893.9 KEG14002.1 - 0.18 11.9 0.8 0.39 10.8 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Cytidylate_kin PF02224.18 KEG14002.1 - 0.32 10.7 2.7 0.21 11.3 0.7 1.7 2 0 0 2 2 2 0 Cytidylate kinase PTPLA PF04387.14 KEG14003.1 - 4.3e-59 198.9 7.3 5.5e-59 198.6 7.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.14 KEG14004.1 - 1.4e-12 48.3 0.0 1.6e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Histone PF00125.24 KEG14005.1 - 2.2e-13 50.7 0.9 2.8e-13 50.3 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEG14005.1 - 0.0035 17.6 0.3 0.0081 16.4 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.22 KEG14005.1 - 0.033 14.2 1.1 0.055 13.5 1.0 1.3 1 1 0 1 1 1 0 GMP synthase C terminal domain Mito_carr PF00153.27 KEG14006.1 - 2e-43 146.3 7.8 1.3e-14 53.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glutaredoxin PF00462.24 KEG14008.1 - 2.3e-13 50.2 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MCM PF00493.23 KEG14009.1 - 1.1e-69 234.0 0.0 1.6e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KEG14009.1 - 9.8e-22 77.2 0.5 2e-21 76.2 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KEG14009.1 - 1.6e-14 53.8 0.8 1.6e-14 53.8 0.8 2.1 2 0 0 2 2 2 1 MCM OB domain AAA_5 PF07728.14 KEG14009.1 - 2.7e-09 37.2 0.0 4.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEG14009.1 - 1.9e-05 24.1 1.3 0.16 11.3 0.4 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEG14009.1 - 0.00058 19.7 0.0 0.0016 18.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KEG14009.1 - 0.017 15.0 2.1 0.044 13.6 0.9 2.3 2 0 0 2 2 2 0 AAA lid domain AAA PF00004.29 KEG14009.1 - 0.026 14.9 0.0 0.086 13.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEG14009.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF4012 PF13196.6 KEG14009.1 - 0.17 12.4 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Ribosomal_S11 PF00411.19 KEG14010.1 - 0.00089 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 SAP25 PF15476.6 KEG14010.1 - 0.023 14.4 1.6 0.041 13.6 1.6 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Pyr_redox_2 PF07992.14 KEG14011.1 - 7.8e-60 202.6 0.0 9.9e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEG14011.1 - 9.2e-25 87.0 0.0 1.6e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEG14011.1 - 1.1e-22 80.3 0.1 5.2e-19 68.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEG14011.1 - 6.1e-12 45.4 0.2 3.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEG14011.1 - 2.7e-06 26.7 0.7 0.017 14.2 0.4 3.0 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 KEG14011.1 - 0.00023 20.0 0.7 0.097 11.4 0.3 3.0 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.22 KEG14011.1 - 0.032 13.3 2.1 0.035 13.2 0.6 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A PALP PF00291.25 KEG14011.1 - 0.046 13.1 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_oxidored PF12831.7 KEG14011.1 - 0.18 11.1 0.2 0.63 9.3 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEG14011.1 - 0.22 10.6 0.1 5.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DEAD PF00270.29 KEG14012.1 - 2.1e-42 144.8 0.0 6.1e-42 143.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14012.1 - 8.2e-26 90.5 0.0 5.3e-25 87.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG14012.1 - 0.00044 20.3 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2840 PF11000.8 KEG14014.1 - 0.44 10.3 3.5 63 3.3 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF2840) DtxR PF18357.1 KEG14014.1 - 3.3 7.5 4.0 2.9e+02 1.2 0.0 4.0 4 0 0 4 4 4 0 Diphteria toxin repressor SH3 domain Pkinase PF00069.25 KEG14015.1 - 2.7e-68 230.2 0.0 3.5e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14015.1 - 2.3e-49 168.0 0.0 4e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 KEG14015.1 - 4.5e-40 133.2 43.8 9e-08 31.6 0.5 8.5 8 0 0 8 8 8 8 MORN repeat Kinase-like PF14531.6 KEG14015.1 - 0.0001 21.7 0.0 0.0069 15.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEG14015.1 - 0.0002 20.2 0.0 0.00035 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEG14015.1 - 0.031 13.2 0.0 0.093 11.6 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KEG14015.1 - 0.036 13.6 0.0 1.2 8.7 0.0 2.2 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KEG14015.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SMC_N PF02463.19 KEG14016.1 - 3.4e-60 203.2 1.9 3.7e-59 199.8 1.9 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEG14016.1 - 4.3e-16 59.3 0.4 2.9e-15 56.6 0.2 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEG14016.1 - 3e-10 40.4 10.3 0.00015 21.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEG14016.1 - 6.9e-09 36.5 16.9 6.9e-09 36.5 16.9 5.6 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KEG14016.1 - 3.7e-06 26.9 6.6 0.00012 21.9 0.0 3.8 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KEG14016.1 - 0.00019 21.1 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEG14016.1 - 0.09 13.3 0.0 0.09 13.3 0.0 5.2 2 2 2 4 4 4 0 ABC transporter Spectrin_like PF18373.1 KEG14016.1 - 3.3 7.8 8.2 24 5.1 2.2 4.5 5 0 0 5 5 5 0 Spectrin like domain TPR_2 PF07719.17 KEG14017.1 - 2.3e-19 67.9 23.3 5e-06 26.2 0.3 9.5 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14017.1 - 3.7e-16 58.2 10.2 7.4e-06 25.6 0.7 7.8 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14017.1 - 1.1e-15 57.9 6.5 2.7e-06 27.8 0.0 5.9 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14017.1 - 1.3e-15 56.7 16.1 0.00054 20.6 0.2 8.5 5 2 4 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG14017.1 - 6.6e-13 48.7 20.5 1.1e-08 35.1 0.5 6.4 6 2 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEG14017.1 - 1.9e-11 43.5 2.0 0.00049 20.3 0.0 6.8 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14017.1 - 3.1e-11 42.6 5.4 0.00011 22.1 0.2 7.4 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14017.1 - 8.7e-11 42.0 18.7 0.0013 19.0 0.9 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEG14017.1 - 2e-09 37.4 13.5 0.12 13.0 0.2 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG14017.1 - 2.4e-08 34.0 11.9 9.9e-05 22.4 0.6 5.7 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14017.1 - 6.4e-07 29.9 19.4 0.00051 20.6 0.2 7.5 5 2 4 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14017.1 - 2.1e-06 27.3 2.7 1.1 9.0 0.1 5.8 2 1 3 5 5 5 2 TPR repeat TPR_7 PF13176.6 KEG14017.1 - 1.1e-05 25.0 7.1 0.12 12.4 0.0 6.0 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEG14017.1 - 0.0016 17.7 0.7 0.031 13.5 0.3 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KEG14017.1 - 0.0018 18.6 0.3 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEG14017.1 - 0.0031 16.9 6.2 0.16 11.3 1.2 3.1 4 0 0 4 4 4 2 MalT-like TPR region BTAD PF03704.17 KEG14017.1 - 0.0037 17.7 3.2 0.0037 17.7 3.2 4.1 5 1 0 5 5 4 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KEG14017.1 - 0.022 13.7 2.1 0.13 11.2 0.1 2.2 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KEG14017.1 - 0.051 13.5 0.6 0.051 13.5 0.6 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEG14017.1 - 0.73 9.9 7.2 0.79 9.8 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KEG14017.1 - 1.7 8.5 4.7 0.55 10.1 0.3 2.5 4 0 0 4 4 3 0 Virulence factor membrane-bound polymerase, C-terminal Tctex-1 PF03645.13 KEG14018.1 - 3.6e-23 81.8 0.1 4e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.28 KEG14019.1 - 8.7e-09 36.2 0.0 1.1e-06 29.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Polysacc_syn_2C PF08485.10 KEG14019.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal RBB1NT PF08169.11 KEG14022.1 - 0.016 15.4 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 RBB1NT (NUC162) domain Pkinase PF00069.25 KEG14023.1 - 5.9e-64 216.0 0.0 7.7e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14023.1 - 4.8e-43 147.3 0.0 7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG14023.1 - 1.4e-11 44.8 0.0 2.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KEG14023.1 - 8.7e-09 35.1 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 KEG14023.1 - 1.3e-07 32.0 0.1 2.7e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 KEG14023.1 - 0.0048 15.7 0.1 0.0077 15.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEG14023.1 - 0.027 13.4 0.8 0.045 12.7 0.8 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KEG14023.1 - 0.11 11.5 0.4 0.15 11.0 0.4 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ANAPC4_WD40 PF12894.7 KEG14024.1 - 0.00011 22.4 0.0 0.64 10.3 0.0 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Robl_LC7 PF03259.17 KEG14025.1 - 2.6e-08 33.5 0.1 3.3e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain GAS PF13851.6 KEG14028.1 - 0.0002 20.7 23.7 0.0002 20.7 23.7 6.5 4 1 3 7 7 7 3 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 KEG14028.1 - 0.011 15.8 8.7 0.011 15.8 8.7 8.7 7 1 0 7 7 7 0 Centrosome localisation domain of PPC89 Acetyltransf_15 PF17013.5 KEG14032.1 - 0.19 11.2 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF1981 PF09324.10 KEG14033.1 - 0.0078 16.1 0.1 0.32 10.9 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1981) HEAT PF02985.22 KEG14033.1 - 0.022 15.0 5.5 12 6.4 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 KEG14036.1 - 0.0037 17.7 0.3 0.0078 16.7 0.3 1.6 1 0 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.6 KEG14036.1 - 0.026 14.9 0.2 0.06 13.7 0.2 1.6 1 1 0 1 1 1 0 HEAT repeats HEAT PF02985.22 KEG14036.1 - 0.03 14.6 0.0 7.1 7.2 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat Autophagy_act_C PF03987.15 KEG14037.1 - 0.0053 17.3 0.3 0.0079 16.8 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DnaJ PF00226.31 KEG14038.1 - 3.7e-18 65.4 0.0 5.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Peptidase_M16 PF00675.20 KEG14039.1 - 7.8e-32 110.3 0.0 1.9e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 KEG14039.1 - 2.8e-21 76.1 0.0 6e-20 71.7 0.0 2.2 1 1 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KEG14039.1 - 3.5e-11 43.4 0.0 2.7e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ribosomal_60s PF00428.19 KEG14039.1 - 0.17 12.5 3.4 0.71 10.5 3.4 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KEG14039.1 - 1.9 9.0 4.0 62 4.1 3.5 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SPRY PF00622.28 KEG14040.1 - 0.0018 18.4 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BTB_2 PF02214.22 KEG14040.1 - 0.0064 16.8 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain FANCI_S2 PF14676.6 KEG14041.1 - 0.016 15.5 2.9 0.044 14.1 2.9 1.8 1 1 0 1 1 1 0 FANCI solenoid 2 RasGAP_C PF03836.15 KEG14041.1 - 0.041 14.0 0.6 0.058 13.6 0.6 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DUF948 PF06103.11 KEG14041.1 - 0.1 12.9 1.5 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FSA_C PF10479.9 KEG14041.1 - 0.17 10.0 3.3 0.24 9.5 3.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Adap_comp_sub PF00928.21 KEG14042.1 - 8.4e-52 176.1 0.0 1.1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEG14042.1 - 9.5e-05 22.4 0.3 0.0002 21.3 0.0 1.7 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF3866 PF12982.7 KEG14044.1 - 0.24 10.5 0.2 0.33 10.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DRAT PF07357.11 KEG14045.1 - 0.084 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) NUDIX_2 PF13869.6 KEG14047.1 - 0.034 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase CSTF1_dimer PF16699.5 KEG14048.1 - 3.8e-06 26.6 0.1 8.9e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain WD40 PF00400.32 KEG14048.1 - 3.8e-06 27.5 0.1 0.14 13.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG14048.1 - 0.00037 20.7 0.0 3.6 7.9 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 KEG14049.1 - 1.5e-30 105.6 11.3 2.2e-08 34.6 0.4 10.3 8 2 4 12 12 12 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG14049.1 - 9.8e-21 73.9 8.8 1.3e-07 32.0 0.6 8.6 8 2 1 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG14049.1 - 2.3e-14 52.1 23.0 0.057 14.0 0.0 13.2 14 0 0 14 14 14 4 Ankyrin repeat Ank PF00023.30 KEG14049.1 - 1.1e-10 41.4 27.8 0.077 13.5 0.1 11.0 12 0 0 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 KEG14049.1 - 5.5e-10 39.3 14.7 0.0036 17.6 0.0 9.3 9 1 2 11 11 11 2 Ankyrin repeats (many copies) SPRY PF00622.28 KEG14049.1 - 1.5e-08 34.8 0.0 3.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 SPRY domain Exonuc_VII_L PF02601.15 KEG14049.1 - 5.5 6.5 7.0 16 4.9 7.0 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit PCI PF01399.27 KEG14050.1 - 1.6e-08 35.0 0.0 6.3e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain ABC_sub_bind PF04392.12 KEG14050.1 - 0.1 11.8 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein Mito_carr PF00153.27 KEG14051.1 - 1.4e-50 169.2 2.6 5.3e-17 61.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KEG14051.1 - 0.0042 17.4 2.2 22 5.5 0.0 4.0 3 1 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Macoilin PF09726.9 KEG14052.1 - 9.3e-07 27.8 29.3 1.9e-06 26.8 9.8 2.5 2 0 0 2 2 2 2 Macoilin family DUF1664 PF07889.12 KEG14052.1 - 0.00015 21.8 9.6 0.18 11.9 1.6 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KEG14052.1 - 0.0022 18.4 11.7 0.76 10.3 0.1 4.9 4 0 0 4 4 4 2 Centrosome microtubule-binding domain of Cep57 DUF2205 PF10224.9 KEG14052.1 - 0.0036 17.3 4.9 0.19 11.7 0.8 3.1 2 0 0 2 2 2 1 Short coiled-coil protein Sec34 PF04136.15 KEG14052.1 - 0.0039 17.1 1.3 0.046 13.6 0.0 2.8 3 0 0 3 3 2 1 Sec34-like family NPV_P10 PF05531.12 KEG14052.1 - 0.014 15.8 10.4 0.022 15.2 2.1 3.9 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Cluap1 PF10234.9 KEG14052.1 - 0.038 13.4 0.1 0.038 13.4 0.1 3.3 3 0 0 3 3 3 0 Clusterin-associated protein-1 SbsC_C PF18058.1 KEG14052.1 - 0.038 14.2 0.5 0.16 12.2 0.5 2.0 1 0 0 1 1 1 0 SbsC C-terminal domain DivIC PF04977.15 KEG14052.1 - 0.12 12.2 10.4 13 5.6 0.0 4.4 3 1 1 4 4 4 0 Septum formation initiator Snapin_Pallidin PF14712.6 KEG14052.1 - 0.37 11.2 18.6 0.08 13.4 0.5 4.4 5 0 0 5 5 4 0 Snapin/Pallidin DivIVA PF05103.13 KEG14052.1 - 0.45 10.6 19.2 0.089 12.9 0.8 4.6 4 1 1 5 5 5 0 DivIVA protein Lebercilin PF15619.6 KEG14052.1 - 0.51 10.0 26.1 22 4.7 0.1 4.5 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 KEG14052.1 - 0.52 10.8 9.8 0.67 10.4 0.0 4.1 4 1 0 4 4 3 0 Type III cell invasion protein SipB DUF948 PF06103.11 KEG14052.1 - 0.62 10.3 9.0 0.77 10.1 3.1 3.8 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2730 PF10805.8 KEG14052.1 - 0.7 10.0 3.9 2.7 8.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) FapA PF03961.13 KEG14052.1 - 0.86 8.1 12.7 5.7 5.4 0.0 3.2 2 1 1 3 3 3 0 Flagellar Assembly Protein A DUF16 PF01519.16 KEG14052.1 - 0.92 10.0 10.8 4.5 7.8 0.7 3.7 3 0 0 3 3 3 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KEG14052.1 - 2.2 8.7 22.4 0.73 10.3 0.6 5.3 6 0 0 6 6 5 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 KEG14052.1 - 2.6 8.6 24.3 0.52 10.8 0.2 5.0 3 1 1 4 4 4 0 Cell division protein ZapB SNCAIP_SNCA_bd PF16700.5 KEG14052.1 - 3.4 7.4 8.6 0.33 10.7 0.6 3.0 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain BLOC1_2 PF10046.9 KEG14052.1 - 4.4 7.7 11.9 5.2 7.4 0.1 4.4 5 0 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 KEG14052.1 - 5.5 7.4 14.1 0.59 10.5 0.1 3.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels P4Ha_N PF08336.11 KEG14052.1 - 5.8 6.9 7.7 4.2 7.4 0.1 3.4 3 1 1 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prefoldin PF02996.17 KEG14052.1 - 8.7 6.3 14.8 12 5.9 0.5 4.8 5 0 0 5 5 5 0 Prefoldin subunit DHR10 PF18595.1 KEG14052.1 - 9.1 6.4 25.6 0.57 10.3 0.6 5.0 4 1 1 5 5 5 0 Designed helical repeat protein 10 domain ANAPC10 PF03256.16 KEG14053.1 - 4.6e-49 166.6 0.0 6.8e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DAGK_cat PF00781.24 KEG14055.1 - 5.2e-12 45.5 0.0 1.3e-05 24.8 0.0 3.3 2 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 KEG14057.1 - 2.9e-41 141.6 0.0 3.6e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14057.1 - 1.1e-29 103.5 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14057.1 - 0.0003 20.2 0.0 0.00068 19.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEG14057.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG14057.1 - 0.0035 16.2 0.0 0.0048 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEG14057.1 - 0.013 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KEG14057.1 - 0.055 12.4 0.6 0.1 11.5 0.3 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase AAA PF00004.29 KEG14058.1 - 1e-39 136.0 0.0 2.4e-39 134.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KEG14058.1 - 1.5e-22 79.3 0.0 4.9e-22 77.7 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KEG14058.1 - 3.8e-19 68.5 3.2 1.1e-18 67.1 3.2 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KEG14058.1 - 1.7e-06 27.8 0.0 1.8e-05 24.4 0.0 2.7 4 0 0 4 4 3 1 AAA+ lid domain AAA_2 PF07724.14 KEG14058.1 - 1.8e-06 28.2 0.0 5.2e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KEG14058.1 - 0.00014 21.9 0.1 0.0023 18.0 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG14058.1 - 0.00077 19.9 0.2 0.067 13.6 0.0 2.9 3 1 1 4 4 3 1 AAA ATPase domain AAA_33 PF13671.6 KEG14058.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG14058.1 - 0.0014 19.0 0.1 0.096 13.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEG14058.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KEG14058.1 - 0.0023 17.7 0.0 0.0076 16.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KEG14058.1 - 0.0041 17.1 0.6 4.9 7.0 0.0 2.9 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KEG14058.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain USP8_dimer PF08969.11 KEG14058.1 - 0.005 17.0 4.4 0.005 17.0 4.4 1.7 2 0 0 2 2 1 1 USP8 dimerisation domain TIP49 PF06068.13 KEG14058.1 - 0.0054 16.0 0.1 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 KEG14058.1 - 0.0074 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEG14058.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KEG14058.1 - 0.018 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KEG14058.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KEG14058.1 - 0.025 15.1 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEG14058.1 - 0.03 14.7 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KEG14058.1 - 0.031 14.0 0.0 0.08 12.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KEG14058.1 - 0.052 13.1 0.1 4.1 6.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain TPR_1 PF00515.28 KEG14058.1 - 0.094 12.6 2.3 0.13 12.2 0.3 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 KEG14058.1 - 0.1 11.9 0.1 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Glyco_transf_88 PF16849.5 KEG14058.1 - 0.11 11.3 0.3 0.23 10.4 0.1 1.4 2 0 0 2 2 2 0 Glycosyltransferase family 88 PhoH PF02562.16 KEG14058.1 - 0.15 11.5 0.1 0.35 10.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein TPR_2 PF07719.17 KEG14058.1 - 2.3 8.5 5.3 0.8 10.0 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PFK PF00365.20 KEG14059.1 - 2.4e-64 217.4 0.1 3e-64 217.1 0.1 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 KEG14059.1 - 9.9e-05 22.0 0.1 0.0002 21.0 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KEG14059.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-NAD kinase TFIIF_alpha PF05793.12 KEG14060.1 - 0.0025 16.5 22.6 0.003 16.2 22.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KEG14060.1 - 0.005 15.2 18.4 0.0061 14.9 18.4 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KEG14060.1 - 0.17 11.3 29.9 0.21 11.0 29.9 1.1 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 KEG14060.1 - 0.68 9.6 37.1 1.1 8.8 37.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hamartin PF04388.12 KEG14060.1 - 1 7.9 6.2 1.3 7.6 6.2 1.2 1 0 0 1 1 1 0 Hamartin protein MDM1 PF15501.6 KEG14060.1 - 1.4 8.0 18.9 1.8 7.6 18.9 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Presenilin PF01080.17 KEG14060.1 - 4.7 5.9 12.6 5.7 5.6 12.6 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 KEG14060.1 - 5.3 5.1 35.0 6.8 4.8 35.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-MIZ PF02891.20 KEG14061.1 - 2.1e-06 27.3 0.4 1.6e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KEG14061.1 - 0.0082 15.9 0.0 0.026 14.4 0.0 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Methyltr_RsmB-F PF01189.17 KEG14063.1 - 5.9e-39 133.8 0.2 1.9e-37 128.9 0.2 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KEG14063.1 - 8.7e-06 26.0 0.2 2e-05 24.8 0.2 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase AcMNPV_Ac109 PF05054.12 KEG14064.1 - 0.0066 15.6 0.1 0.0077 15.4 0.1 1.1 1 0 0 1 1 1 1 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Peptidase_A4 PF01828.17 KEG14064.1 - 0.023 14.2 0.7 0.029 13.8 0.5 1.3 1 1 0 1 1 1 0 Peptidase A4 family Orbi_NS1 PF01718.16 KEG14064.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 2 0 0 2 2 2 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein TPR_19 PF14559.6 KEG14065.1 - 9.2e-20 70.9 28.2 2.1e-08 34.5 2.5 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14065.1 - 7.6e-10 38.8 19.2 0.046 14.5 1.6 8.7 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14065.1 - 1.5e-09 37.2 15.0 0.0021 18.1 0.1 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14065.1 - 1.6e-08 34.0 5.7 0.028 14.2 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG14065.1 - 1.8e-08 34.5 11.8 3.1 8.1 0.2 7.2 5 2 3 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KEG14065.1 - 2.7e-08 34.0 24.2 0.00086 19.5 0.1 7.8 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14065.1 - 7.1e-07 28.8 4.0 0.00027 20.6 1.2 4.2 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 KEG14065.1 - 0.00049 20.1 1.2 15 6.1 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14065.1 - 0.0053 17.1 10.8 0.18 12.2 0.3 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KEG14065.1 - 0.0098 15.3 0.8 0.39 10.1 0.0 3.1 3 0 0 3 3 3 1 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 KEG14065.1 - 0.012 15.3 11.0 0.031 13.9 1.0 4.6 3 2 3 6 6 6 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 KEG14065.1 - 0.02 15.5 11.5 22 6.0 0.0 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEG14065.1 - 0.11 12.9 3.8 10 6.5 0.1 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TAF1_subA PF14929.6 KEG14065.1 - 0.14 11.6 1.1 0.34 10.3 0.1 2.1 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A TPR_9 PF13371.6 KEG14065.1 - 1 9.5 9.3 8.6 6.6 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4586 PF15239.6 KEG14066.1 - 2.8e-57 195.2 10.5 3.9e-57 194.7 10.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.25 KEG14067.1 - 5.8e-69 232.4 0.1 1e-68 231.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14067.1 - 4e-48 163.9 0.0 6.4e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14067.1 - 8.7e-07 28.5 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEG14067.1 - 0.0013 18.7 0.1 0.28 11.1 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG14067.1 - 0.056 12.2 0.0 0.13 11.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase DCX PF03607.17 KEG14070.1 - 1.4e-13 50.7 0.1 2.4e-05 24.3 0.1 2.7 2 0 0 2 2 2 2 Doublecortin KHA PF11834.8 KEG14070.1 - 0.00024 21.1 0.0 0.13 12.4 0.0 3.0 3 0 0 3 3 3 2 KHA, dimerisation domain of potassium ion channel Mucin PF01456.17 KEG14070.1 - 1.9 8.4 58.7 1.2 9.1 15.9 3.5 3 0 0 3 3 3 0 Mucin-like glycoprotein MGC-24 PF05283.11 KEG14070.1 - 2.6 8.5 27.2 1.2 9.5 3.9 3.7 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PAP_central PF04928.17 KEG14072.1 - 3e-28 98.5 0.0 4.3e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KEG14072.1 - 0.0023 17.6 0.1 0.028 14.1 0.0 2.0 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain Atg14 PF10186.9 KEG14073.1 - 0.95 8.5 7.2 3.3 6.7 0.5 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KEG14073.1 - 2 8.5 16.2 3.2 7.8 2.4 4.1 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding AKNA PF12443.8 KEG14073.1 - 2 9.1 9.6 9.9 6.9 0.0 4.2 4 0 0 4 4 4 0 AT-hook-containing transcription factor LPP PF04728.13 KEG14073.1 - 2.7 8.4 6.6 6.4 7.2 0.3 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Med30 PF11315.8 KEG14073.1 - 7.6 6.7 12.6 1.2 9.4 4.5 3.0 3 0 0 3 3 3 0 Mediator complex subunit 30 SAM_2 PF07647.17 KEG14075.1 - 5.3e-06 26.4 0.1 1.4e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEG14075.1 - 5.1e-05 23.6 0.6 0.00018 21.9 0.3 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Trp_dioxygenase PF03301.13 KEG14075.1 - 0.031 13.6 0.4 0.08 12.3 0.4 1.6 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase DUF2730 PF10805.8 KEG14075.1 - 0.1 12.7 0.5 2 8.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) SAM_Ste50p PF09235.10 KEG14075.1 - 0.12 12.6 0.2 0.93 9.8 0.0 2.7 2 0 0 2 2 2 0 Ste50p, sterile alpha motif MPS2 PF17060.5 KEG14076.1 - 0.26 10.5 3.3 0.37 10.0 3.3 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Ras PF00071.22 KEG14077.1 - 1e-37 129.3 0.0 1.4e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG14077.1 - 3.3e-28 98.3 0.0 5.1e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG14077.1 - 2e-15 56.7 0.0 2.9e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG14077.1 - 7.9e-05 22.1 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG14077.1 - 0.00038 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KEG14077.1 - 0.0079 15.9 0.2 0.025 14.3 0.1 1.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KEG14077.1 - 0.011 15.0 0.1 0.58 9.2 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KEG14077.1 - 0.013 15.5 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KEG14077.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Aldedh PF00171.22 KEG14078.1 - 1.3e-86 290.9 0.0 1.5e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Noelin-1 PF12308.8 KEG14079.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein Herpes_UL6 PF01763.16 KEG14080.1 - 0.0094 14.5 0.5 0.0094 14.5 0.5 1.7 2 0 0 2 2 2 1 Herpesvirus UL6 like DUF4337 PF14235.6 KEG14080.1 - 1.9 8.6 12.3 6.1 6.9 2.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) Fungal_TACC PF12709.7 KEG14080.1 - 4.7 7.7 9.9 0.13 12.7 0.8 2.8 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Lzipper-MIP1 PF14389.6 KEG14080.1 - 5.3 7.4 17.7 0.6 10.5 2.0 3.8 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 KLRAQ PF10205.9 KEG14080.1 - 9 6.6 15.9 0.13 12.5 2.3 3.1 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein Kelch_6 PF13964.6 KEG14082.1 - 1.5e-18 66.4 5.1 5.4e-05 23.3 0.1 7.2 7 1 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 KEG14082.1 - 1.3e-14 54.0 7.6 0.06 13.4 0.3 6.8 5 3 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KEG14082.1 - 2.6e-09 37.1 16.1 0.012 15.9 0.2 6.2 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG14082.1 - 6.8e-09 35.5 12.4 0.13 12.3 0.2 6.4 5 2 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KEG14082.1 - 1.4e-08 34.2 21.6 9.2e-06 25.2 0.1 7.1 7 2 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 KEG14082.1 - 5.3e-06 26.2 9.0 0.0005 19.9 0.4 5.0 6 0 0 6 6 6 2 Kelch motif CLASP_N PF12348.8 KEG14083.1 - 1.3e-13 51.0 4.1 6.5e-09 35.7 0.5 5.7 6 1 0 6 6 6 2 CLASP N terminal HEAT PF02985.22 KEG14083.1 - 3e-06 27.0 7.4 8 7.0 0.0 9.4 10 0 0 10 10 10 1 HEAT repeat NUC173 PF08161.12 KEG14083.1 - 4.1e-06 26.6 0.3 0.035 13.8 0.0 3.7 2 1 1 3 3 3 2 NUC173 domain AIM3 PF17096.5 KEG14084.1 - 0.14 13.1 2.4 0.2 12.6 2.4 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 IFT46_B_C PF12317.8 KEG14085.1 - 1.1e-77 260.6 0.1 1.7e-77 260.0 0.1 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Pkinase PF00069.25 KEG14086.1 - 1.5e-37 129.4 0.0 2.5e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14086.1 - 2.6e-14 53.1 0.0 4.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG14086.1 - 0.00027 20.9 0.1 0.0013 18.7 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG14086.1 - 0.0032 16.5 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KEG14086.1 - 0.024 14.2 0.0 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 KEG14086.1 - 0.047 13.0 0.0 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KEG14086.1 - 0.061 12.1 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ART PF01129.18 KEG14086.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DnaJ PF00226.31 KEG14087.1 - 0.02 15.0 0.4 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 DnaJ domain TGT PF01702.18 KEG14088.1 - 1.5e-126 422.3 0.0 7.8e-95 318.0 0.0 2.4 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase ubiquitin PF00240.23 KEG14089.1 - 0.053 13.3 0.0 0.072 12.9 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin family YukD PF08817.10 KEG14089.1 - 0.077 13.7 0.0 0.088 13.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ASH PF15780.5 KEG14090.1 - 1.2e-50 169.7 60.4 9.3e-05 22.6 0.1 28.8 31 0 0 31 31 31 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KEG14090.1 - 1.3e-18 67.0 21.4 0.013 15.7 0.0 14.2 17 0 0 17 17 17 3 Flagellar-associated PapD-like MYCBPAP PF14646.6 KEG14090.1 - 1.5e-16 60.4 2.9 0.0032 16.5 0.0 9.6 10 0 0 10 10 10 4 MYCBP-associated protein family DUF1573 PF07610.11 KEG14090.1 - 1.9e-14 53.4 4.5 1.1 9.4 0.1 14.2 17 0 0 17 17 17 4 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 KEG14090.1 - 4.2e-12 45.9 12.7 0.14 12.0 0.0 13.8 18 0 0 18 18 18 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KEG14090.1 - 4.3e-10 39.7 17.5 0.0004 20.6 0.1 10.4 13 0 0 13 13 13 3 Transmembrane protein 131-like DUF5001 PF16392.5 KEG14090.1 - 6.3e-06 26.0 2.4 0.42 10.6 0.1 6.1 5 0 0 5 5 5 1 Ig-like domain ADK PF00406.22 KEG14090.1 - 0.0029 17.7 0.0 0.009 16.1 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase Transglut_C PF00927.22 KEG14090.1 - 0.057 13.6 0.1 30 4.8 0.0 4.9 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain adh_short PF00106.25 KEG14091.1 - 7.9e-16 58.1 0.0 6.1e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEG14091.1 - 1e-12 48.1 0.0 8.4e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Arm PF00514.23 KEG14092.1 - 0.0055 16.7 0.1 0.025 14.6 0.0 2.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat GldM_N PF12081.8 KEG14092.1 - 1.1 9.3 5.1 0.62 10.1 0.4 2.3 2 1 0 2 2 2 0 GldM N-terminal domain DUF5133 PF17196.4 KEG14092.1 - 1.4 9.2 10.3 7.7 6.8 2.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF5133) Ribosomal_S16 PF00886.19 KEG14093.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 Dockerin_1 PF00404.18 KEG14094.1 - 7.4e-08 32.5 0.9 0.01 16.0 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_5 PF13202.6 KEG14094.1 - 1.4e-07 30.6 1.2 0.017 14.6 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 KEG14094.1 - 9.4e-07 28.0 0.8 0.086 12.4 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KEG14094.1 - 2.6e-05 23.8 2.4 0.046 13.7 0.1 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KEG14094.1 - 0.00021 21.7 0.3 0.86 10.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair FUN14 PF04930.15 KEG14094.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 FUN14 family Exo_endo_phos PF03372.23 KEG14095.1 - 4.7e-12 45.9 0.1 1.3e-11 44.5 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DivIC PF04977.15 KEG14096.1 - 0.007 16.1 3.1 0.007 16.1 3.1 4.9 1 1 3 4 4 4 3 Septum formation initiator Syntaxin_2 PF14523.6 KEG14096.1 - 0.0098 16.2 12.4 0.26 11.7 0.5 3.6 1 1 2 3 3 3 2 Syntaxin-like protein PRKG1_interact PF15898.5 KEG14096.1 - 1 10.3 32.4 4.4 8.2 5.0 3.4 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain NPV_P10 PF05531.12 KEG14096.1 - 1.4 9.4 11.7 3.6 8.1 0.6 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 KEG14096.1 - 3 7.1 23.0 0.27 10.6 13.5 2.4 1 1 1 2 2 2 0 FAM76 protein APG6_N PF17675.1 KEG14096.1 - 5 7.7 39.1 0.18 12.3 17.5 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1843 PF08898.10 KEG14096.1 - 8.7 6.9 11.8 19 5.9 0.9 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) Ribonuc_red_lgC PF02867.15 KEG14097.1 - 5.3e-183 609.3 0.0 7.2e-183 608.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KEG14097.1 - 1.7e-22 79.2 0.0 4.4e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KEG14097.1 - 5e-10 39.8 0.0 1.4e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 KEG14097.1 - 0.056 13.7 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein WD40 PF00400.32 KEG14099.1 - 0.12 13.3 0.2 8.9 7.4 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Gmad1 PF10647.9 KEG14099.1 - 0.18 11.5 1.8 0.38 10.5 0.0 2.4 3 1 1 4 4 4 0 Lipoprotein LpqB beta-propeller domain MCM PF00493.23 KEG14101.1 - 3.6e-94 314.1 0.0 5.8e-94 313.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEG14101.1 - 8.9e-36 122.5 0.2 1.6e-35 121.7 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEG14101.1 - 1e-26 93.2 0.3 3e-26 91.6 0.3 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEG14101.1 - 7.4e-09 36.1 0.3 7.4e-09 36.1 0.3 2.5 3 0 0 3 3 3 1 MCM N-terminal domain MCM2_N PF12619.8 KEG14101.1 - 2.2e-06 28.1 22.9 2.2e-06 28.1 22.9 2.7 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KEG14101.1 - 2.2e-06 27.2 0.0 0.00013 21.5 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEG14101.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEG14101.1 - 0.00061 19.7 0.0 0.0085 15.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M13_N PF05649.13 KEG14101.1 - 0.0057 16.4 0.5 0.045 13.4 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M13 AAA_lid_2 PF17863.1 KEG14101.1 - 0.015 15.1 1.8 0.043 13.7 0.0 2.6 2 0 0 2 2 2 0 AAA lid domain Sigma54_activat PF00158.26 KEG14101.1 - 0.075 12.7 0.1 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF1738 PF08401.11 KEG14102.1 - 0.00021 21.4 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) RNF220 PF15926.5 KEG14103.1 - 0.026 14.1 0.9 0.034 13.8 0.9 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 CSD PF00313.22 KEG14105.1 - 5.5e-17 61.4 0.8 7.1e-17 61.0 0.8 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Stm1_N PF09598.10 KEG14105.1 - 0.047 14.5 0.5 0.079 13.8 0.5 1.4 1 1 0 1 1 1 0 Stm1 DUF3273 PF11677.8 KEG14106.1 - 0.12 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) PP_kinase_C PF13090.6 KEG14107.1 - 0.053 13.0 0.3 0.096 12.1 0.3 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 RNA_pol_Rpb8 PF03870.15 KEG14108.1 - 2.1e-36 125.2 0.0 2.3e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KEG14108.1 - 0.0069 16.4 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G EF-hand_9 PF14658.6 KEG14109.1 - 1.3e-17 63.9 0.1 5e-17 62.0 0.0 1.9 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KEG14109.1 - 4.1e-10 40.0 0.0 7.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG14109.1 - 3.8e-08 32.3 0.1 0.015 14.8 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KEG14109.1 - 4.4e-07 29.3 0.0 0.0039 17.0 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KEG14109.1 - 0.0015 18.3 2.6 4 7.4 0.1 3.9 2 1 2 4 4 4 2 EF-hand domain pair Nsp1 PF11501.8 KEG14109.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Non structural protein Nsp1 DSPc PF00782.20 KEG14110.1 - 2.8e-18 66.0 0.0 5.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAP_assoc PF03828.19 KEG14111.1 - 8.4e-14 51.5 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Peptidase_M32 PF02074.15 KEG14113.1 - 3.1e-28 98.8 0.1 3.4e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Soyouz_module PF14313.6 KEG14113.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) NUC173 PF08161.12 KEG14114.1 - 4.1e-18 65.8 0.1 6.8e-17 61.8 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain UDPGP PF01704.18 KEG14115.1 - 1.8e-26 92.7 0.0 2.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MTS PF05175.14 KEG14117.1 - 0.12 11.9 0.0 5.3 6.5 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase small domain Radial_spoke PF04712.12 KEG14119.1 - 6e-05 22.2 0.0 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 2 Radial spokehead-like protein Rad51 PF08423.11 KEG14121.1 - 7.5e-38 130.2 0.0 7.6e-23 81.1 0.0 3.5 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.6 KEG14121.1 - 1.1e-11 44.7 0.2 1.4e-10 41.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KEG14121.1 - 1.1e-05 24.9 0.0 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 1 KaiC RecA PF00154.21 KEG14121.1 - 1.4e-05 24.7 0.1 0.00013 21.6 0.1 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Eno-Rase_NADH_b PF12242.8 KEG14121.1 - 0.00025 20.7 0.0 0.00059 19.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_33 PF13671.6 KEG14121.1 - 0.002 18.3 0.3 0.041 14.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEG14121.1 - 0.023 15.1 0.0 0.091 13.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEG14121.1 - 0.024 14.4 0.0 0.41 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEG14121.1 - 0.029 14.8 0.1 0.22 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KEG14121.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KEG14121.1 - 0.15 12.0 0.5 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 KEG14121.1 - 0.23 11.0 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region CDK2AP PF09806.9 KEG14121.1 - 0.24 11.5 3.8 0.21 11.6 2.0 1.7 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein EF-hand_8 PF13833.6 KEG14123.1 - 0.0028 17.4 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair APH PF01636.23 KEG14123.1 - 0.023 14.6 1.3 0.046 13.6 1.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_1 PF00036.32 KEG14123.1 - 0.029 13.9 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KEG14123.1 - 0.038 14.4 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KEG14123.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KEG14123.1 - 0.18 11.8 0.1 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Ribosomal_60s PF00428.19 KEG14123.1 - 3.4 8.3 16.0 0.59 10.8 9.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein BRCT PF00533.26 KEG14126.1 - 0.084 13.3 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain TFIIA PF03153.13 KEG14126.1 - 0.36 10.8 31.1 1.2 9.1 20.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3420 PF11900.8 KEG14127.1 - 0.00092 19.3 5.4 0.68 10.1 0.1 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF3420) CmcI PF04989.12 KEG14127.1 - 0.061 13.0 2.2 0.099 12.3 0.4 2.1 2 0 0 2 2 2 0 Cephalosporin hydroxylase zf-MYND PF01753.18 KEG14129.1 - 1.9e-11 43.9 34.7 1.2e-05 25.3 12.1 2.6 2 0 0 2 2 2 2 MYND finger Diphthamide_syn PF01866.17 KEG14130.1 - 3.8e-41 141.5 0.4 6.5e-20 71.8 0.0 2.4 3 0 0 3 3 3 2 Putative diphthamide synthesis protein MMR_HSR1 PF01926.23 KEG14131.1 - 3.2e-17 62.6 0.5 9e-13 48.3 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG14131.1 - 7e-12 45.1 0.6 1.1e-08 34.8 0.4 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEG14131.1 - 1.8e-05 24.7 0.1 0.00029 20.8 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KEG14131.1 - 5.6e-05 23.3 3.0 0.015 15.4 0.2 3.1 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KEG14131.1 - 0.0019 17.8 0.1 0.015 14.9 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KEG14131.1 - 0.014 15.9 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain LuxT_C PF18285.1 KEG14131.1 - 0.025 15.1 0.0 0.078 13.5 0.0 1.9 1 1 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain MeaB PF03308.16 KEG14131.1 - 0.034 13.1 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HSP90 PF00183.18 KEG14132.1 - 4.1e-96 322.9 1.5 1.5e-94 317.8 0.2 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KEG14132.1 - 2e-12 47.1 0.0 5.6e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEG14132.1 - 5.1e-07 30.2 0.0 1.1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPRP PF04244.13 KEG14132.1 - 0.017 15.0 0.2 0.031 14.1 0.2 1.3 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein RWD PF05773.22 KEG14132.1 - 0.038 14.3 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 RWD domain Ribosomal_S19e PF01090.19 KEG14134.1 - 2.9e-44 150.1 0.0 3.5e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 KEG14134.1 - 0.001 19.2 0.1 0.003 17.7 0.0 1.8 2 0 0 2 2 2 1 Mrr N-terminal domain SRP68 PF16969.5 KEG14135.1 - 1.8e-55 189.0 16.2 2.7e-32 112.5 10.3 3.1 1 1 1 3 3 3 3 RNA-binding signal recognition particle 68 DUF3484 PF11983.8 KEG14135.1 - 0.18 12.9 1.2 0.51 11.5 1.2 1.7 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Peptidase_M14 PF00246.24 KEG14136.1 - 2.7e-17 63.5 0.0 9.6e-17 61.7 0.0 1.8 1 1 1 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KEG14136.1 - 3.4e-09 37.0 0.0 8.3e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KEG14136.1 - 0.00044 19.4 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family cNMP_binding PF00027.29 KEG14137.1 - 2.6e-24 85.1 0.2 6.9e-13 48.5 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Urm1 PF09138.11 KEG14138.1 - 7.3e-27 93.6 0.0 8.2e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KEG14138.1 - 1.5e-06 28.7 0.0 1.8e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family GTP_EFTU PF00009.27 KEG14139.1 - 2.1e-27 96.0 0.0 3.6e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEG14139.1 - 1.2e-07 31.8 0.1 6.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KEG14139.1 - 1.1e-06 28.9 0.4 3.4e-06 27.3 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 KEG14139.1 - 0.00075 19.3 0.3 0.36 10.6 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KEG14139.1 - 0.0025 17.3 0.0 0.015 14.8 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 KEG14139.1 - 0.0082 15.8 0.6 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KEG14139.1 - 0.035 13.6 0.0 0.082 12.4 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Hexapep PF00132.24 KEG14140.1 - 1.3e-10 40.6 11.0 9.5e-07 28.3 1.8 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEG14140.1 - 0.0067 16.2 9.6 0.02 14.6 2.0 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L3 PF00297.22 KEG14143.1 - 1.1e-150 501.8 7.1 1.2e-150 501.6 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.22 KEG14144.1 - 4.9e-07 30.1 0.7 3e-06 27.6 0.7 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase PPR PF01535.20 KEG14144.1 - 0.16 12.3 0.9 5 7.6 0.1 2.8 2 0 0 2 2 2 0 PPR repeat Thioredoxin PF00085.20 KEG14146.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PTEN_C2 PF10409.9 KEG14147.1 - 2.2e-13 50.1 0.0 4.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.6 KEG14147.1 - 1.8e-05 24.8 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KEG14147.1 - 2.5e-05 24.5 0.0 5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KEG14147.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KEG14147.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KEG14147.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Cys_rich_FGFR PF00839.17 KEG14147.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Cysteine rich repeat IpgD PF05925.12 KEG14147.1 - 0.27 9.7 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD PDZ_6 PF17820.1 KEG14149.1 - 2.9e-08 33.4 0.6 7.3e-08 32.2 0.6 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEG14149.1 - 4.1e-07 30.3 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KEG14149.1 - 6.5e-07 29.6 0.3 8.2e-06 26.1 0.1 2.5 2 0 0 2 2 2 1 PDZ domain zf-ZPR1 PF03367.13 KEG14149.1 - 0.026 14.4 1.1 0.051 13.4 1.1 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Tropomyosin_1 PF12718.7 KEG14149.1 - 1.3 9.1 9.1 0.18 12.0 4.6 1.8 2 0 0 2 2 2 0 Tropomyosin like PspA_IM30 PF04012.12 KEG14149.1 - 1.5 8.4 12.1 0.21 11.1 5.8 2.5 2 1 1 3 3 3 0 PspA/IM30 family EF-hand_7 PF13499.6 KEG14150.1 - 2.8e-14 53.3 0.4 9.6e-05 22.8 0.0 4.8 4 2 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KEG14150.1 - 8.8e-11 40.8 1.0 0.0064 16.3 0.0 6.4 7 0 0 7 7 7 2 EF-hand domain EF-hand_1 PF00036.32 KEG14150.1 - 1.3e-10 40.1 2.2 0.016 14.7 0.0 6.6 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KEG14150.1 - 1.3e-09 37.7 0.5 1.3e-05 24.9 0.0 4.6 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 KEG14150.1 - 0.00011 21.5 11.4 0.24 11.0 0.0 6.1 8 0 0 8 8 8 2 EF hand Golgin_A5 PF09787.9 KEG14151.1 - 0.023 14.2 11.0 0.029 13.8 11.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 tRNA-synt_1d PF00750.19 KEG14151.1 - 0.032 13.2 1.0 0.037 13.0 1.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) Goodbye PF17109.5 KEG14151.1 - 0.34 11.4 6.6 1.5 9.3 1.5 2.1 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Atg14 PF10186.9 KEG14151.1 - 0.51 9.4 11.9 0.67 9.0 11.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KEG14151.1 - 1.5 8.1 9.0 1.8 7.9 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KEG14151.1 - 1.8 8.0 6.9 2.1 7.9 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 KEG14151.1 - 7.2 5.0 6.3 7.9 4.9 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSDR_N_2 PF13588.6 KEG14152.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N PF04313.14 KEG14152.1 - 0.071 13.0 0.8 0.15 12.0 0.3 1.7 2 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) NDK PF00334.19 KEG14153.1 - 9.5e-23 80.7 0.0 2.7e-22 79.2 0.0 1.8 3 0 0 3 3 3 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 KEG14153.1 - 0.00017 21.4 0.2 0.00076 19.3 0.2 2.0 1 1 0 1 1 1 1 DUF1126 PH-like domain Rhodanese PF00581.20 KEG14154.1 - 1.1e-11 45.2 0.0 2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF3997 PF13162.6 KEG14154.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Pkinase PF00069.25 KEG14155.1 - 6.7e-20 71.6 0.0 7.8e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KEG14155.1 - 0.0019 18.2 0.0 0.026 14.5 0.0 2.4 2 2 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG14155.1 - 0.0036 16.1 0.0 0.0085 14.9 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEG14155.1 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 KEG14155.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase RMP PF14996.6 KEG14156.1 - 5.2e-10 39.8 4.6 8.4e-10 39.1 0.3 2.8 3 1 0 3 3 3 1 Retinal Maintenance Beta_helix PF13229.6 KEG14157.1 - 3.3e-06 27.0 0.0 8.2e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 KEG14157.1 - 0.00036 19.9 0.0 0.00072 18.9 0.0 1.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.17 KEG14157.1 - 0.072 11.8 8.8 0.095 11.4 3.7 2.1 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Cyt-b5 PF00173.28 KEG14158.1 - 1.8e-06 28.0 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4160 PF13711.6 KEG14158.1 - 0.11 12.9 0.0 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) ResIII PF04851.15 KEG14159.1 - 7.2e-17 61.9 0.0 1.2e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T5orf172 PF10544.9 KEG14159.1 - 1.6e-09 38.2 0.0 3.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain Helicase_C PF00271.31 KEG14159.1 - 4.6e-08 33.4 0.0 1.4e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEG14159.1 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase MUG113 PF13455.6 KEG14159.1 - 0.034 14.8 0.1 0.17 12.5 0.0 2.3 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 OrsD PF12013.8 KEG14159.1 - 0.053 14.0 0.8 0.15 12.5 0.8 1.8 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D TPR_19 PF14559.6 KEG14160.1 - 0.042 14.3 0.6 0.11 13.1 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14160.1 - 0.28 11.8 2.9 0.74 10.5 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.24 KEG14161.1 - 2.2e-05 24.3 12.2 0.00012 21.9 3.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG14161.1 - 8.3e-05 22.5 14.2 0.00025 21.0 6.5 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KEG14161.1 - 0.0033 17.2 3.3 0.0033 17.2 3.3 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 KEG14161.1 - 0.059 14.1 2.3 0.059 14.1 2.3 2.2 1 1 1 2 2 2 0 Torus domain zf-CCHH PF10283.9 KEG14161.1 - 2 8.5 6.6 0.76 9.8 1.8 2.3 2 0 0 2 2 2 0 PBZ domain HAD_SAK_2 PF18143.1 KEG14164.1 - 6.8e-26 91.3 0.0 9.4e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins GCS PF03074.16 KEG14165.1 - 6.1e-137 456.9 0.1 8.2e-137 456.4 0.1 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase DnaJ PF00226.31 KEG14166.1 - 3.3e-12 46.3 0.0 9.9e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KEG14166.1 - 0.00037 20.2 0.9 3.8 7.5 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14166.1 - 0.0022 18.0 7.1 3.7 7.9 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14166.1 - 0.24 12.1 8.2 18 6.0 0.5 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14166.1 - 0.58 10.5 11.2 0.59 10.5 0.6 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG14166.1 - 2.5 8.4 6.5 2.2 8.6 0.5 3.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KEG14166.1 - 9.9 7.3 10.8 31 5.7 0.6 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SidC_N PF18219.1 KEG14168.1 - 0.014 14.4 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 SidC N-terminal domain MatE PF01554.18 KEG14169.1 - 4.4e-41 140.2 28.4 4e-28 98.1 10.3 2.5 2 0 0 2 2 2 2 MatE Flavi_NS4A PF01350.17 KEG14169.1 - 7.4 6.5 13.4 1 9.3 0.1 3.4 2 1 2 4 4 4 0 Flavivirus non-structural protein NS4A Got1 PF04178.12 KEG14171.1 - 2.2e-12 47.4 14.4 2.8e-12 47.1 14.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family SdpI PF13630.6 KEG14171.1 - 2 8.6 6.3 6.2 7.0 0.8 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3784 PF12650.7 KEG14171.1 - 2.1 8.6 9.3 9.3 6.5 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3592 PF12158.8 KEG14171.1 - 10 6.2 10.8 14 5.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3592) Noc2 PF03715.13 KEG14172.1 - 2.2e-90 303.0 0.1 2.2e-90 303.0 0.1 1.7 2 0 0 2 2 2 1 Noc2p family Isy1 PF06246.12 KEG14172.1 - 4.1 6.9 16.6 0.091 12.3 10.1 1.6 2 0 0 2 2 2 0 Isy1-like splicing family Kinesin PF00225.23 KEG14173.1 - 4.3e-62 210.0 0.1 1e-61 208.8 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG14173.1 - 9.2e-10 38.6 0.0 2.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Longin PF13774.6 KEG14174.1 - 4.3e-20 71.5 0.1 8e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.13 KEG14174.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PsbX PF06596.11 KEG14174.1 - 0.19 11.8 3.9 0.37 10.8 3.9 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) zf-C3HC4_3 PF13920.6 KEG14175.1 - 5.4e-12 45.4 17.0 9.7e-12 44.6 17.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG14175.1 - 3.8e-05 23.5 17.1 6.8e-05 22.6 17.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SlyX PF04102.12 KEG14175.1 - 0.055 14.1 0.2 0.09 13.4 0.2 1.3 1 0 0 1 1 1 0 SlyX Fib_alpha PF08702.10 KEG14177.1 - 0.12 12.5 1.7 0.24 11.6 0.6 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cauli_AT PF03233.13 KEG14177.1 - 0.19 11.7 0.1 17 5.3 0.0 2.6 2 1 0 2 2 2 0 Aphid transmission protein DUF16 PF01519.16 KEG14177.1 - 0.2 12.1 0.9 1.1 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 UAA PF08449.11 KEG14178.1 - 4.5e-49 167.3 7.6 4.4e-31 108.2 0.4 2.0 2 0 0 2 2 2 2 UAA transporter family PUNUT PF16913.5 KEG14178.1 - 0.00052 19.3 2.8 0.00052 19.3 2.8 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KEG14178.1 - 0.0097 14.9 2.1 0.012 14.6 0.2 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Kinesin PF00225.23 KEG14179.1 - 1.7e-59 201.4 0.5 5.9e-59 199.7 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG14179.1 - 1.3e-12 47.9 1.8 2e-12 47.3 0.0 2.3 3 0 0 3 3 3 1 Microtubule binding AAA_24 PF13479.6 KEG14179.1 - 0.017 14.9 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEG14179.1 - 0.021 15.1 1.6 0.14 12.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KEG14179.1 - 0.27 11.6 0.0 0.27 11.6 0.0 4.5 3 2 0 4 4 4 0 AAA ATPase domain BST2 PF16716.5 KEG14179.1 - 2.9 8.5 43.0 0.019 15.6 4.8 6.1 3 1 2 6 6 6 0 Bone marrow stromal antigen 2 LSM14 PF12701.7 KEG14182.1 - 5.3e-27 93.7 0.0 8.7e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KEG14182.1 - 3e-06 27.3 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KEG14182.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 KEG14182.1 - 0.1 13.3 10.4 0.18 12.5 10.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family DUF5578 PF17741.1 KEG14183.1 - 4.6e-30 104.9 0.0 9.3e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5578) DnaJ PF00226.31 KEG14184.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase2 PF03162.13 KEG14185.1 - 5.1e-39 133.5 0.0 6.4e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KEG14185.1 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF5113 PF17140.4 KEG14186.1 - 0.03 14.1 0.2 0.042 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Cyclin_N PF00134.23 KEG14187.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF4148 PF13663.6 KEG14187.1 - 1.8 8.8 5.4 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF2475 PF10629.9 KEG14190.1 - 0.001 19.3 0.6 0.0025 18.0 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) Raptor_N PF14538.6 KEG14191.1 - 4.3e-48 163.0 0.0 1.2e-47 161.5 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KEG14191.1 - 5.6e-05 23.1 5.3 0.066 13.5 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KEG14191.1 - 0.034 14.5 0.0 0.37 11.2 0.0 2.6 2 1 0 2 2 2 0 HEAT repeats EcsC PF12787.7 KEG14191.1 - 0.053 13.2 0.5 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 EcsC protein family Cnd1 PF12717.7 KEG14191.1 - 0.064 13.3 0.1 0.52 10.3 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KEG14191.1 - 3.2 8.4 7.1 44 4.7 0.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat RNA_pol_Rpb2_6 PF00562.28 KEG14192.1 - 1.9e-71 241.2 0.0 4.4e-71 240.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KEG14192.1 - 3.4e-19 68.8 0.1 1.2e-18 67.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KEG14192.1 - 6.1e-14 52.2 0.4 2.2e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 KEG14192.1 - 3.4e-11 43.0 0.0 1e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 KEG14192.1 - 3e-07 30.2 0.0 7.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase beta subunit zinc_ribbon_10 PF10058.9 KEG14192.1 - 0.061 13.1 0.2 0.2 11.4 0.2 1.9 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein RNA_pol_Rpb2_4 PF04566.13 KEG14192.1 - 0.095 13.0 0.1 0.38 11.1 0.0 2.2 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Mod_r PF07200.13 KEG14192.1 - 0.78 9.8 7.2 7.8 6.6 0.5 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PPR PF01535.20 KEG14193.1 - 0.00047 20.2 1.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 KEG14193.1 - 0.0035 17.5 0.5 0.01 16.0 0.1 2.0 2 0 0 2 2 2 1 PPR repeat family PPPI_inhib PF14895.6 KEG14193.1 - 0.03 13.5 0.3 5.7 6.0 0.0 2.1 1 1 1 2 2 2 0 Protein phosphatase 1 inhibitor PPR_long PF17177.4 KEG14193.1 - 0.039 13.3 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP DUF4071 PF13281.6 KEG14193.1 - 0.052 12.6 0.4 0.057 12.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PPR_1 PF12854.7 KEG14193.1 - 0.087 12.5 0.3 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 PPR repeat PPR_3 PF13812.6 KEG14193.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DUF4164 PF13747.6 KEG14194.1 - 0.097 13.0 2.7 0.11 12.8 1.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) zf-AN1 PF01428.16 KEG14195.1 - 0.00049 20.2 24.7 0.0035 17.5 6.0 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger Nfu_N PF08712.11 KEG14195.1 - 0.0076 16.3 0.0 6.4 6.9 0.0 2.7 1 1 2 3 3 3 2 Scaffold protein Nfu/NifU N terminal CAP_N PF01213.19 KEG14195.1 - 0.33 10.4 1.4 0.59 9.6 1.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ENTH PF01417.20 KEG14196.1 - 2.4e-26 92.2 0.0 3.6e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Ribosomal_L21e PF01157.18 KEG14197.1 - 1.1e-41 140.7 3.0 1.7e-41 140.2 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Alpha_kinase PF02816.18 KEG14198.1 - 1e-54 185.5 0.0 1.4e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SF-assemblin PF06705.11 KEG14201.1 - 0.0026 17.1 8.4 0.025 13.9 3.6 2.1 1 1 1 2 2 2 2 SF-assemblin/beta giardin RF-1 PF00472.20 KEG14201.1 - 0.12 12.4 0.9 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 RF-1 domain SCAMP PF04144.13 KEG14202.1 - 4.4e-35 121.5 8.6 5.4e-35 121.2 8.6 1.1 1 0 0 1 1 1 1 SCAMP family Tetraspanin PF00335.20 KEG14202.1 - 0.54 9.9 6.4 1.1 8.9 6.4 1.5 1 0 0 1 1 1 0 Tetraspanin family Dynein_light PF01221.18 KEG14203.1 - 1e-41 141.1 0.9 1.1e-41 141.0 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 KEG14203.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 48 ECSIT PF06239.11 KEG14203.1 - 0.036 13.2 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Vasohibin PF14822.6 KEG14203.1 - 0.082 12.1 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 Vasohibin Ectatomin PF06457.11 KEG14203.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Ectatomin TACC_C PF05010.14 KEG14204.1 - 0.29 10.9 4.0 4.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SM-ATX PF14438.6 KEG14205.1 - 0.006 16.7 0.5 0.0092 16.1 0.1 1.7 2 1 0 2 2 2 1 Ataxin 2 SM domain LSM PF01423.22 KEG14205.1 - 0.043 13.5 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 LSM domain Pkinase PF00069.25 KEG14206.1 - 3.3e-60 203.7 0.0 1.3e-59 201.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14206.1 - 2.5e-28 99.1 0.0 6.8e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG14206.1 - 3.5e-08 33.1 0.0 0.002 17.5 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 KEG14206.1 - 0.00026 20.1 0.1 0.00037 19.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEG14206.1 - 0.00055 19.4 0.2 0.00086 18.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG14206.1 - 0.0012 17.8 0.1 0.0038 16.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KEG14206.1 - 0.0043 17.0 0.1 0.0064 16.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEG14206.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KEG14206.1 - 0.11 11.4 0.2 0.22 10.4 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PP2C PF00481.21 KEG14207.1 - 7.1e-68 229.0 0.0 8.6e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEG14207.1 - 0.0036 17.3 0.0 0.052 13.5 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEG14207.1 - 0.007 16.0 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF327 PF03885.13 KEG14208.1 - 0.14 12.1 0.4 6.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Mito_carr PF00153.27 KEG14209.1 - 4.8e-88 289.3 15.5 1.7e-19 69.5 0.0 6.4 5 2 1 6 6 6 6 Mitochondrial carrier protein Serine_protease PF18405.1 KEG14209.1 - 0.00022 20.5 2.2 1.5 7.9 0.1 4.3 4 2 1 5 5 5 3 Gammaproteobacterial serine protease TPR_1 PF00515.28 KEG14210.1 - 1.4e-22 78.5 13.1 5.8e-06 25.9 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat DnaJ PF00226.31 KEG14210.1 - 3.7e-20 71.8 0.6 3.7e-20 71.8 0.6 2.3 2 1 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 KEG14210.1 - 5.9e-19 66.6 23.7 2.7e-05 23.9 0.0 8.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14210.1 - 8.3e-15 54.2 11.4 1.5e-06 27.7 0.0 6.4 6 1 1 7 7 7 3 TPR repeat TPR_16 PF13432.6 KEG14210.1 - 7.3e-13 48.9 15.2 0.0023 18.5 0.1 5.9 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14210.1 - 7.5e-12 44.5 13.8 0.034 14.4 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG14210.1 - 6.5e-10 38.3 6.1 0.11 12.6 0.3 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14210.1 - 1.6e-09 38.1 13.6 0.2 12.2 0.1 6.5 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14210.1 - 2e-09 37.5 10.4 0.2 12.6 0.0 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14210.1 - 1.1e-07 32.0 11.8 0.24 11.7 0.2 6.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEG14210.1 - 3.5e-07 30.3 3.5 0.013 15.6 0.4 4.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14210.1 - 0.00017 21.7 2.7 7.9 7.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 KEG14210.1 - 0.00064 19.7 3.2 2.6 8.2 0.0 5.2 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KEG14210.1 - 0.0011 18.8 10.1 2.9 7.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEG14210.1 - 0.0039 16.5 10.3 0.089 12.0 2.5 3.7 3 2 1 4 4 4 1 Tetratricopeptide repeat HemY_N PF07219.13 KEG14210.1 - 0.016 15.4 0.2 0.016 15.4 0.2 4.7 4 1 1 5 5 5 0 HemY protein N-terminus Fis1_TPR_C PF14853.6 KEG14210.1 - 0.035 14.2 4.0 0.8 9.8 0.0 4.5 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KEG14210.1 - 0.08 13.6 3.7 68 4.4 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 KEG14210.1 - 0.11 12.8 0.3 56 4.3 0.0 3.8 3 0 0 3 3 3 0 PPR repeat Transcrip_act PF04949.13 KEG14210.1 - 0.51 10.2 5.4 1.2 9.0 0.3 3.4 4 0 0 4 4 4 0 Transcriptional activator zf-C2HC_2 PF13913.6 KEG14211.1 - 3e-11 42.9 10.2 1.1e-08 34.8 2.4 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-WRNIP1_ubi PF18279.1 KEG14211.1 - 0.031 14.9 0.1 0.096 13.4 0.1 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-C2H2_4 PF13894.6 KEG14211.1 - 0.05 14.4 1.9 11 7.1 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ANAPC11 PF12861.7 KEG14212.1 - 0.052 13.6 0.8 0.088 12.9 0.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dus PF01207.17 KEG14213.1 - 3.8e-32 111.6 0.2 8.1e-31 107.3 0.2 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Tnp_P_element PF12017.8 KEG14213.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Transposase protein Sec1 PF00995.23 KEG14214.1 - 1e-107 361.8 1.7 1.3e-107 361.5 1.7 1.1 1 0 0 1 1 1 1 Sec1 family DUF5421 PF17458.2 KEG14214.1 - 0.04 13.3 2.3 0.093 12.1 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5421) DHC_N2 PF08393.13 KEG14214.1 - 0.07 12.2 0.1 0.15 11.1 0.1 1.6 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 AATF-Che1 PF13339.6 KEG14215.1 - 0.24 12.1 3.8 0.16 12.6 1.3 1.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor FAST_1 PF06743.15 KEG14216.1 - 2.5e-05 24.2 0.1 0.068 13.1 0.0 3.0 2 0 0 2 2 2 2 FAST kinase-like protein, subdomain 1 ANTH PF07651.16 KEG14216.1 - 0.15 11.0 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 ANTH domain TFIIA_gamma_N PF02268.16 KEG14217.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KEG14217.1 - 0.0065 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Aa_trans PF01490.18 KEG14218.1 - 2e-50 171.7 36.6 2.4e-50 171.5 36.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEG14218.1 - 0.0048 16.0 36.3 0.032 13.3 36.3 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family PDZ PF00595.24 KEG14220.1 - 5.4e-05 23.5 0.0 0.0002 21.6 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KEG14220.1 - 0.0001 22.6 1.3 0.00021 21.5 0.3 2.0 2 0 0 2 2 2 1 PDZ domain Dynactin_p22 PF07426.11 KEG14220.1 - 0.014 15.2 2.4 0.02 14.7 0.4 2.0 2 1 0 2 2 2 0 Dynactin subunit p22 GRASP55_65 PF04495.14 KEG14220.1 - 0.017 15.4 0.0 3.8 7.8 0.0 2.3 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain DB_JBP1 PF18526.1 KEG14223.1 - 2.8e-06 27.4 0.2 2.8e-06 27.4 0.2 3.0 2 1 1 3 3 3 1 Thymine dioxygenase JBP1 DNA-binding domain Cu-binding_MopE PF11617.8 KEG14225.1 - 8.1e-07 29.1 2.5 2e-06 27.8 2.5 1.7 1 0 0 1 1 1 1 Putative metal-binding motif Lipase_GDSL_2 PF13472.6 KEG14225.1 - 1.2e-06 29.1 0.0 2.5e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEG14225.1 - 6.7e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sigma_reg_C PF13791.6 KEG14225.1 - 0.005 17.1 0.1 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 Sigma factor regulator C-terminal CDC73_C PF05179.14 KEG14225.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal Pantoate_ligase PF02569.15 KEG14226.1 - 5.5e-96 320.9 0.0 6.2e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PIP5K PF01504.18 KEG14227.1 - 1.3e-55 188.6 0.0 1.7e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EMC3_TMCO1 PF01956.16 KEG14228.1 - 5e-48 163.1 6.0 2.5e-47 160.7 6.0 1.8 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF5326 PF17260.2 KEG14228.1 - 0.072 13.2 0.3 0.17 12.0 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Plasmid_RAQPRD PF09686.10 KEG14229.1 - 0.36 11.1 1.6 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) IQ PF00612.27 KEG14229.1 - 0.42 10.5 3.8 0.59 10.1 0.5 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-DNL PF05180.12 KEG14230.1 - 0.024 14.5 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 DNL zinc finger NESP55 PF06390.12 KEG14230.1 - 0.14 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF4763 PF15960.5 KEG14231.1 - 0.0016 17.8 3.7 0.0016 17.8 3.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) Yuri_gagarin PF15934.5 KEG14231.1 - 0.0061 16.4 0.3 1.9 8.3 0.1 2.2 2 0 0 2 2 2 2 Yuri gagarin zinc_ribbon_16 PF17034.5 KEG14231.1 - 0.011 15.9 1.4 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon like family DUF2968 PF11180.8 KEG14231.1 - 0.02 14.6 5.4 0.02 14.6 5.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) Cortex-I_coil PF09304.10 KEG14231.1 - 0.024 14.9 1.9 0.11 12.8 0.2 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil KfrA_N PF11740.8 KEG14231.1 - 0.047 14.4 9.9 1.1 10.0 5.1 2.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term JIP_LZII PF16471.5 KEG14231.1 - 0.071 13.3 4.1 0.95 9.7 0.9 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 KEG14231.1 - 0.14 11.5 4.6 0.85 8.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KEG14231.1 - 0.15 12.7 5.9 0.22 12.1 1.8 3.0 2 1 0 2 2 2 0 SlyX Cytochrom_B558a PF05038.13 KEG14231.1 - 0.15 11.6 1.6 0.82 9.2 0.6 2.2 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Herpes_UL6 PF01763.16 KEG14231.1 - 0.25 9.8 0.2 5.4 5.4 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like CorA PF01544.18 KEG14231.1 - 0.49 9.7 1.6 0.87 8.8 0.1 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TBCC_N PF16752.5 KEG14231.1 - 0.64 10.5 3.8 1.8 9.0 0.2 2.8 3 0 0 3 3 2 0 Tubulin-specific chaperone C N-terminal domain DegS PF05384.11 KEG14231.1 - 1.4 8.3 6.7 0.61 9.6 0.5 2.2 2 0 0 2 2 2 0 Sensor protein DegS VCX_VCY PF15231.6 KEG14231.1 - 2.5 8.8 14.9 0.16 12.6 9.4 1.8 2 0 0 2 2 2 0 Variable charge X/Y family HXXSHH PF07586.11 KEG14231.1 - 5.1 6.6 8.8 0.1 12.2 1.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) GSP_synth PF03738.14 KEG14232.1 - 3.8e-72 243.5 0.0 5e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 KEG14232.1 - 2.2e-09 37.8 0.0 6e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 CHAP domain CAP_N PF01213.19 KEG14233.1 - 0.19 11.2 1.2 0.31 10.5 1.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mre11_DNA_bind PF04152.14 KEG14234.1 - 5e-31 108.3 0.0 1.2e-30 107.1 0.0 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KEG14234.1 - 4e-11 43.8 3.9 1.8e-10 41.7 3.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIA PF03153.13 KEG14234.1 - 2.2 8.2 7.0 3.6 7.5 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF846 PF05832.12 KEG14236.1 - 3.7e-43 146.9 11.3 4.4e-43 146.6 11.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SdpI PF13630.6 KEG14236.1 - 0.047 13.8 0.2 0.047 13.8 0.2 2.0 2 0 0 2 2 2 0 SdpI/YhfL protein family Wzy_C PF04932.15 KEG14236.1 - 0.1 12.3 3.3 0.82 9.3 0.4 2.2 2 0 0 2 2 2 0 O-Antigen ligase DUF4191 PF13829.6 KEG14236.1 - 1.6 8.0 3.5 12 5.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Halogen_Hydrol PF10112.9 KEG14236.1 - 3.3 7.7 5.6 10 6.1 0.3 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein zf-MIZ PF02891.20 KEG14237.1 - 2.4e-20 72.0 0.4 5e-20 71.0 0.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger ANAPC15 PF15243.6 KEG14237.1 - 0.048 14.1 1.9 0.048 14.1 1.9 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 CDC45 PF02724.14 KEG14237.1 - 0.13 10.5 3.5 0.21 9.8 3.5 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KEG14237.1 - 0.14 10.7 3.7 0.22 10.0 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-Nse PF11789.8 KEG14237.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SH3_4 PF06347.13 KEG14237.1 - 0.35 10.7 4.4 0.46 10.4 0.0 3.1 4 0 0 4 4 4 0 Bacterial SH3 domain PGA2 PF07543.12 KEG14237.1 - 0.43 10.5 4.1 0.91 9.5 4.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 zf-C3HC4_3 PF13920.6 KEG14237.1 - 1 9.3 5.2 0.51 10.2 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PTPRCAP PF15713.5 KEG14237.1 - 5 7.4 11.6 0.46 10.8 6.7 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CHCH PF06747.13 KEG14238.1 - 6 7.1 13.0 0.82 9.9 0.3 3.9 4 0 0 4 4 4 0 CHCH domain PPR PF01535.20 KEG14239.1 - 0.1 12.9 0.0 27 5.3 0.0 3.6 4 0 0 4 4 4 0 PPR repeat PPR_2 PF13041.6 KEG14239.1 - 0.19 11.9 0.1 1.8 8.8 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family MLANA PF14991.6 KEG14240.1 - 0.0028 17.9 9.7 0.0046 17.2 0.6 3.5 2 1 1 3 3 3 2 Protein melan-A TagA PF12561.8 KEG14241.1 - 0.15 12.4 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain Pkinase PF00069.25 KEG14242.1 - 1.8e-51 175.1 0.0 2.8e-45 154.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14242.1 - 1.2e-25 90.3 0.0 4.2e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG14242.1 - 3.6e-05 23.2 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEG14242.1 - 0.00063 18.8 0.1 0.001 18.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KEG14242.1 - 0.03 13.1 0.8 0.053 12.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KEG14242.1 - 0.11 12.3 1.8 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEG14242.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Dpy-30 PF05186.13 KEG14243.1 - 1.5e-06 27.7 0.2 2.9e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 KEG14243.1 - 0.0022 18.1 0.0 0.0099 16.0 0.0 2.1 1 0 0 1 1 1 1 Adenylate kinase Helitron_like_N PF14214.6 KEG14243.1 - 0.035 14.3 0.6 0.47 10.7 0.7 2.4 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus BUD22 PF09073.10 KEG14243.1 - 0.72 9.1 48.6 0.0079 15.6 27.9 3.3 3 0 0 3 3 3 0 BUD22 HGTP_anticodon2 PF12745.7 KEG14243.1 - 1.8 8.0 15.3 0.048 13.2 1.3 3.5 3 0 0 3 3 3 0 Anticodon binding domain of tRNAs IFT43 PF15305.6 KEG14244.1 - 2.4e-07 31.0 1.3 7e-07 29.5 1.3 1.9 1 0 0 1 1 1 1 Intraflagellar transport protein 43 LSM PF01423.22 KEG14245.1 - 1.8e-16 59.6 0.4 2.3e-16 59.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.19 KEG14246.1 - 2.2e-55 187.5 0.0 3.8e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 KEG14246.1 - 1.7e-28 99.7 20.7 1.7e-28 99.7 20.7 3.6 2 2 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 KEG14246.1 - 7.4e-27 94.2 10.8 7.4e-27 94.2 10.8 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) RabGAP-TBC PF00566.18 KEG14247.1 - 5.8e-27 94.7 0.0 7.2e-26 91.2 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TRAM1 PF08390.11 KEG14247.1 - 0.17 11.6 0.2 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 TRAM1-like protein Pet191_N PF10203.9 KEG14248.1 - 4.5e-09 36.5 1.2 6.4e-09 36.0 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HATPase_c PF02518.26 KEG14249.1 - 0.00092 19.7 0.0 0.0036 17.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TIR PF01582.20 KEG14250.1 - 0.009 15.8 1.3 0.014 15.2 1.3 1.3 1 0 0 1 1 1 1 TIR domain DDE_Tnp_4 PF13359.6 KEG14251.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease AAA_6 PF12774.7 KEG14252.1 - 5.9e-155 515.2 0.0 5.2e-154 512.1 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KEG14252.1 - 1.9e-139 465.9 5.0 1.9e-139 465.9 5.0 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KEG14252.1 - 6.8e-109 364.6 8.4 6.8e-109 364.6 8.4 3.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG14252.1 - 1.4e-101 339.2 0.0 4.2e-101 337.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KEG14252.1 - 3.4e-82 276.1 0.3 8.4e-82 274.8 0.3 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KEG14252.1 - 3.9e-76 255.0 0.0 3.9e-76 255.0 0.0 3.0 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KEG14252.1 - 6.1e-66 221.4 2.8 1.3e-61 207.3 0.1 4.5 4 1 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG14252.1 - 2.9e-54 183.3 0.4 7e-54 182.0 0.4 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG14252.1 - 4.4e-43 146.2 0.0 1e-41 141.8 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KEG14252.1 - 3.2e-40 138.2 12.1 4.2e-40 137.8 10.9 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KEG14252.1 - 2e-27 95.9 2.2 2.6e-07 30.7 0.0 7.4 7 1 0 7 7 6 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KEG14252.1 - 1.4e-23 83.4 0.0 1.1e-22 80.4 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KEG14252.1 - 5.9e-17 61.7 0.0 3.3e-16 59.3 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KEG14252.1 - 3.6e-10 40.4 3.0 0.53 10.7 0.0 6.5 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG14252.1 - 4.8e-10 40.1 3.1 0.11 12.9 0.0 6.3 5 1 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KEG14252.1 - 2.4e-07 31.1 10.7 0.019 15.2 0.0 6.4 7 0 0 7 7 6 2 AAA domain ABC_tran PF00005.27 KEG14252.1 - 0.0003 21.3 1.2 1.3 9.6 0.0 4.3 4 0 0 4 4 3 1 ABC transporter AAA_18 PF13238.6 KEG14252.1 - 0.00045 20.8 0.2 2.9 8.5 0.0 4.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KEG14252.1 - 0.0005 19.8 1.2 5.2 6.7 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 KEG14252.1 - 0.00055 19.6 0.4 0.085 12.6 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEG14252.1 - 0.00057 19.8 0.3 0.031 14.2 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase Sigma54_activat PF00158.26 KEG14252.1 - 0.0039 16.9 0.0 2.6 7.7 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain T2SSE PF00437.20 KEG14252.1 - 0.0047 16.0 0.4 5.7 5.9 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Rad17 PF03215.15 KEG14252.1 - 0.0076 16.2 0.4 5.4 6.9 0.0 3.9 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_33 PF13671.6 KEG14252.1 - 0.0081 16.3 4.0 26 5.0 0.0 5.6 6 0 0 6 6 6 0 AAA domain RNA_helicase PF00910.22 KEG14252.1 - 0.013 15.9 0.2 14 6.1 0.0 3.9 3 0 0 3 3 3 0 RNA helicase DUF815 PF05673.13 KEG14252.1 - 0.02 14.0 0.1 10 5.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 KEG14252.1 - 0.17 12.3 0.0 0.17 12.3 0.0 5.5 7 0 0 7 7 4 0 AAA domain AAA_19 PF13245.6 KEG14252.1 - 1.8 8.9 7.4 24 5.2 0.0 4.3 5 0 0 5 5 3 0 AAA domain DnaJ PF00226.31 KEG14253.1 - 4.7e-17 61.9 0.2 8.8e-17 61.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 KEG14253.1 - 3.9e-16 58.1 2.4 0.00012 21.7 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14253.1 - 1e-12 47.1 13.3 0.0042 17.1 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14253.1 - 3.9e-08 32.9 2.3 0.025 14.8 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14253.1 - 1.6e-05 24.9 2.2 0.039 14.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14253.1 - 8.8e-05 23.1 8.9 0.3 11.8 0.6 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14253.1 - 0.00017 22.1 8.5 0.82 10.7 0.3 6.5 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14253.1 - 0.00085 19.0 3.8 9.6 6.0 0.0 5.5 7 0 0 7 7 7 1 TPR repeat TPR_15 PF13429.6 KEG14253.1 - 0.0015 17.8 0.2 0.0038 16.5 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 KEG14253.1 - 0.013 15.6 0.3 3 8.0 0.0 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KEG14253.1 - 0.17 12.4 5.5 14 6.2 0.0 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14253.1 - 0.25 11.6 17.7 1.2 9.4 0.3 5.7 2 2 4 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG14253.1 - 3 8.1 9.1 4.3 7.6 0.5 4.0 2 2 1 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KEG14253.1 - 3.8 8.0 10.9 2.6 8.5 1.7 3.6 3 2 0 3 3 3 0 Bacterial transcriptional activator domain LSM PF01423.22 KEG14254.1 - 3.6e-12 45.8 0.2 4.3e-12 45.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEG14254.1 - 1.1e-06 28.7 0.1 1.5e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KEG14254.1 - 0.024 14.7 0.1 0.031 14.4 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain MIP PF00230.20 KEG14255.1 - 1.5e-29 103.3 17.8 1.4e-28 100.2 17.8 2.0 1 1 0 1 1 1 1 Major intrinsic protein F-box-like PF12937.7 KEG14256.1 - 0.024 14.5 4.2 0.025 14.5 0.3 2.5 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 KEG14256.1 - 0.057 13.3 0.6 0.18 11.8 0.6 1.8 1 1 0 1 1 1 0 F-box domain Ribosomal_L18 PF17135.4 KEG14256.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e APG6_N PF17675.1 KEG14257.1 - 0.091 13.3 19.5 1.6 9.3 0.1 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2536 PF10750.9 KEG14257.1 - 0.13 12.1 10.6 0.08 12.9 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) MOLO1 PF17175.4 KEG14257.1 - 0.77 9.9 2.8 0.76 9.9 0.1 2.2 2 1 1 3 3 3 0 Modulator of levamisole receptor-1 FlaC_arch PF05377.11 KEG14257.1 - 1.5 9.3 0.1 1.5 9.3 0.1 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MnmE_helical PF12631.7 KEG14257.1 - 2 8.5 9.4 5.3 7.2 9.0 1.9 1 1 1 2 2 2 0 MnmE helical domain Fib_alpha PF08702.10 KEG14257.1 - 2.3 8.4 10.4 0.69 10.1 1.2 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF812 PF05667.11 KEG14257.1 - 3 6.6 19.7 3 6.6 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) UPF0449 PF15136.6 KEG14257.1 - 3.5 8.2 13.7 0.98 9.9 0.6 3.1 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 DUF4570 PF15134.6 KEG14257.1 - 9.4 6.3 16.4 0.17 11.9 7.4 2.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4570) TPR_1 PF00515.28 KEG14258.1 - 6.6e-14 51.0 4.8 0.00017 21.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14258.1 - 2.5e-11 42.8 3.2 0.0094 16.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14258.1 - 4.2e-09 36.6 0.4 0.00022 21.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14258.1 - 4.1e-06 27.3 0.7 0.11 13.1 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14258.1 - 7.1e-06 25.6 0.1 0.0066 16.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 KEG14258.1 - 5e-05 23.7 0.1 0.054 14.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KEG14258.1 - 0.00063 20.2 0.9 0.84 10.1 0.0 2.2 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_8 PF13181.6 KEG14258.1 - 0.00082 19.4 1.5 2.9 8.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14258.1 - 0.0014 19.2 0.3 0.4 11.6 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG14258.1 - 0.0029 18.1 0.3 1.3 9.8 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Arfaptin PF06456.13 KEG14258.1 - 0.0038 16.8 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Arfaptin-like domain ANAPC3 PF12895.7 KEG14258.1 - 0.01 16.0 3.2 0.17 12.2 0.7 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEG14258.1 - 0.018 15.4 0.7 1.3 9.5 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG14258.1 - 0.036 14.1 1.2 18 5.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KEG14258.1 - 0.062 13.4 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KEG14258.1 - 0.1 12.5 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L14 PF00238.19 KEG14259.1 - 2.4e-22 79.3 0.1 6e-22 78.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e Complex1_LYR PF05347.15 KEG14260.1 - 0.085 12.9 0.3 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) ANAPC4_WD40 PF12894.7 KEG14262.1 - 6.7e-07 29.5 0.1 0.049 13.9 0.0 5.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG14262.1 - 0.0012 19.6 0.1 0.018 15.9 0.1 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Hira PF07569.11 KEG14262.1 - 0.06 13.1 1.1 0.94 9.2 0.0 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split Zn_ribbon_2 PF12674.7 KEG14262.1 - 0.074 13.7 0.1 0.25 12.0 0.1 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain ANAPC3 PF12895.7 KEG14262.1 - 0.12 12.6 1.6 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ELYS PF13934.6 KEG14262.1 - 0.17 11.8 3.0 0.33 10.9 0.4 2.2 2 0 0 2 2 2 0 Nuclear pore complex assembly PGM_PMM_IV PF00408.20 KEG14263.1 - 3.8e-06 27.0 0.0 7.4e-06 26.1 0.0 1.6 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 KEG14264.1 - 8.3e-40 135.7 0.0 2e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KEG14264.1 - 1.8e-19 70.2 0.1 9.7e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KEG14264.1 - 2.8e-13 50.1 0.1 5.3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Actin PF00022.19 KEG14266.1 - 1.9e-42 145.3 0.0 2.6e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Actin Chordopox_RPO7 PF05864.12 KEG14266.1 - 0.042 14.1 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zinc_ribbon_2 PF13240.6 KEG14267.1 - 0.02 14.6 0.0 0.02 14.6 0.0 3.1 3 1 1 4 4 4 0 zinc-ribbon domain DUF5136 PF17199.4 KEG14267.1 - 0.36 10.5 4.6 0.2 11.4 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) TMEM65 PF10507.9 KEG14268.1 - 8.9e-29 99.6 0.4 1.1e-28 99.3 0.4 1.2 1 0 0 1 1 1 1 Transmembrane protein 65 Aa_trans PF01490.18 KEG14269.1 - 1.3e-34 119.6 30.6 1.6e-34 119.4 30.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MuF_C PF18819.1 KEG14269.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage MuF-C-terminal domain SET PF00856.28 KEG14270.1 - 2.2e-06 28.2 0.0 9.5e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF4442 PF14539.6 KEG14271.1 - 0.024 14.8 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT PF03061.22 KEG14271.1 - 0.054 13.8 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Thioesterase superfamily E3_UFM1_ligase PF09743.9 KEG14272.1 - 9.6e-75 251.7 0.0 1.7e-74 250.9 0.0 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 CHAD PF05235.14 KEG14272.1 - 0.03 14.3 14.2 0.022 14.8 2.7 3.0 1 1 1 2 2 2 0 CHAD domain KfrA_N PF11740.8 KEG14272.1 - 0.81 10.4 9.7 0.1 13.3 3.6 2.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term AFG1_ATPase PF03969.16 KEG14273.1 - 2e-57 194.7 0.0 3.7e-56 190.6 0.0 2.0 2 0 0 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.6 KEG14273.1 - 0.016 15.6 0.3 2.8 8.3 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain Bac_DnaA PF00308.18 KEG14273.1 - 0.18 11.6 0.0 0.91 9.3 0.0 2.1 2 1 0 2 2 2 0 Bacterial dnaA protein NIF PF03031.18 KEG14274.1 - 3.3e-34 117.9 0.0 4.4e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 KEG14274.1 - 0.0046 17.3 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEG14274.1 - 0.0072 16.7 0.2 0.02 15.3 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 4HB PF17947.1 KEG14274.1 - 0.073 13.1 0.6 0.53 10.4 0.1 2.3 3 0 0 3 3 3 0 Four helical bundle domain DUF705 PF05152.12 KEG14274.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Caps_synth_GfcC PF06251.11 KEG14274.1 - 0.17 11.5 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Capsule biosynthesis GfcC Adaptin_N PF01602.20 KEG14275.1 - 1.9e-103 346.8 0.3 2.6e-103 346.4 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEG14275.1 - 3.9e-44 150.5 0.3 1.3e-41 142.3 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEG14275.1 - 4.7e-08 33.3 0.1 3.4e-05 24.2 0.0 4.0 3 1 1 4 4 4 1 HEAT repeats B2-adapt-app_C PF09066.10 KEG14275.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 KEG14275.1 - 0.0028 17.7 5.3 0.93 9.9 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat VHS PF00790.19 KEG14275.1 - 0.066 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 VHS domain OSCP PF00213.18 KEG14276.1 - 8.8e-09 35.7 2.4 1.7e-07 31.6 2.1 2.5 2 1 0 2 2 2 1 ATP synthase delta (OSCP) subunit Lyase_aromatic PF00221.19 KEG14277.1 - 1.5e-186 620.6 0.3 1.7e-186 620.4 0.3 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Gmx_para_CXXCG PF09535.10 KEG14277.1 - 0.077 12.2 0.3 0.58 9.4 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Peptidase_S9_N PF02897.15 KEG14278.1 - 1.6e-97 326.9 0.0 2.1e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KEG14278.1 - 3.1e-63 213.1 0.0 4.8e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KEG14278.1 - 1.9e-05 24.4 0.0 4.7e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.20 KEG14278.1 - 0.0012 18.6 0.1 0.044 13.4 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KEG14278.1 - 0.0054 16.7 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 KEG14278.1 - 0.039 12.6 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KEG14278.1 - 0.1 12.2 0.8 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KEG14278.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEG14278.1 - 0.16 11.2 0.2 0.43 9.8 0.1 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 tRNA-synt_1c PF00749.21 KEG14280.1 - 0.075 11.9 0.0 0.19 10.6 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain EF-hand_7 PF13499.6 KEG14280.1 - 0.095 13.2 0.2 2.2 8.8 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 KEG14280.1 - 0.11 12.5 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain E1_4HB PF16191.5 KEG14280.1 - 0.15 12.2 0.0 7 6.9 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Mito_carr PF00153.27 KEG14281.1 - 1.6e-49 165.8 0.4 2.9e-16 59.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SpoV PF08183.11 KEG14281.1 - 0.028 14.4 0.2 0.39 10.7 0.1 2.4 2 0 0 2 2 2 0 Stage V sporulation protein family Serine_protease PF18405.1 KEG14281.1 - 0.04 13.1 0.0 1.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Keratin_assoc PF09775.9 KEG14281.1 - 0.11 12.1 0.1 18 5.0 0.0 3.3 3 1 0 4 4 4 0 Keratinocyte-associated protein 2 DNA_pol3_delta2 PF13177.6 KEG14282.1 - 5.8e-15 55.4 0.0 9.2e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KEG14282.1 - 2e-09 38.0 0.0 6.1e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEG14282.1 - 1.6e-06 28.2 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KEG14282.1 - 8.1e-05 22.8 0.0 0.019 15.1 0.1 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KEG14282.1 - 0.00063 20.2 0.1 0.0049 17.3 0.0 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEG14282.1 - 0.00073 19.5 0.1 0.0045 17.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KEG14282.1 - 0.002 17.9 0.0 0.0051 16.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KEG14282.1 - 0.026 14.3 0.0 0.6 9.8 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain RuvB_N PF05496.12 KEG14282.1 - 0.026 14.3 0.0 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KEG14282.1 - 0.057 13.7 0.5 3.3 8.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 KEG14282.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DUF815 PF05673.13 KEG14282.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KEG14282.1 - 0.14 12.4 0.2 1.9 8.8 0.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KEG14284.1 - 0.00078 19.9 1.2 0.006 17.0 0.5 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEG14284.1 - 0.0044 17.3 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEG14284.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEG14284.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KEG14284.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 KEG14284.1 - 0.24 11.3 0.0 0.47 10.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Solute_trans_a PF03619.16 KEG14285.1 - 5.2e-79 265.5 20.8 6.9e-79 265.1 20.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4231 PF14015.6 KEG14285.1 - 0.49 10.9 3.7 0.69 10.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Fib_alpha PF08702.10 KEG14286.1 - 0.0022 18.2 7.2 0.0022 18.2 7.2 1.5 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KEG14286.1 - 0.014 14.3 22.2 0.017 14.0 22.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KEG14286.1 - 0.025 14.7 24.0 0.081 13.0 14.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-K PF11802.8 KEG14286.1 - 0.062 12.9 18.3 0.076 12.6 18.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Seryl_tRNA_N PF02403.22 KEG14286.1 - 0.29 11.4 18.3 0.53 10.5 5.3 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 KEG14286.1 - 0.45 8.4 8.9 0.52 8.2 8.9 1.0 1 0 0 1 1 1 0 Prominin IMD PF08397.11 KEG14286.1 - 0.58 9.5 16.1 0.089 12.2 1.4 2.1 1 1 1 2 2 2 0 IRSp53/MIM homology domain Fmp27_WPPW PF10359.9 KEG14286.1 - 0.59 8.9 10.2 0.69 8.7 10.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain End3 PF12761.7 KEG14286.1 - 0.59 10.3 20.2 0.12 12.5 15.2 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TMPIT PF07851.13 KEG14286.1 - 0.64 9.2 8.4 0.73 9.0 8.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 KEG14286.1 - 0.77 10.0 9.1 0.39 11.0 2.4 2.5 1 1 1 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 KEG14286.1 - 0.79 8.6 6.8 0.91 8.4 6.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 KEG14286.1 - 1.4 6.7 13.2 1.7 6.5 13.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KEG14286.1 - 1.5 9.3 6.5 2 8.9 3.4 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Ax_dynein_light PF10211.9 KEG14286.1 - 1.6 8.6 20.1 0.51 10.3 4.4 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain APG6_N PF17675.1 KEG14286.1 - 1.7 9.2 24.9 2.2 8.8 17.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF148 PF02520.17 KEG14286.1 - 1.8 8.7 11.3 0.27 11.3 7.4 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 FapA PF03961.13 KEG14286.1 - 2.1 6.9 11.6 1.8 7.1 10.5 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KEG14286.1 - 2.5 7.6 12.8 3.8 7.0 12.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CcdA PF07362.12 KEG14286.1 - 3.1 8.3 7.9 1.8 9.1 4.4 2.4 2 1 1 3 3 3 0 Post-segregation antitoxin CcdA TMF_DNA_bd PF12329.8 KEG14286.1 - 3.7 7.6 18.9 6.2 6.9 6.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ly49 PF08391.10 KEG14286.1 - 4.9 7.5 12.0 3.2 8.1 9.8 1.8 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region DUF465 PF04325.13 KEG14286.1 - 5.4 7.1 16.3 0.24 11.5 5.2 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF465) CENP-Q PF13094.6 KEG14286.1 - 6.9 6.8 23.6 3 8.0 15.8 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cyt-b5 PF00173.28 KEG14287.1 - 1.5e-13 50.6 0.1 2e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FtsJ PF01728.19 KEG14288.1 - 1.3e-26 93.8 0.0 1.7e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Metalloenzyme PF01676.18 KEG14290.1 - 2e-79 266.5 0.0 2.3e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KEG14290.1 - 3e-60 203.3 0.0 4.4e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) PglZ PF08665.12 KEG14290.1 - 0.004 17.3 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 PglZ domain Phosphodiest PF01663.22 KEG14290.1 - 0.0088 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3659 PF12396.8 KEG14290.1 - 0.15 12.0 0.4 0.58 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) DUF4448 PF14610.6 KEG14291.1 - 0.062 13.1 0.2 0.078 12.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) PET117 PF15786.5 KEG14291.1 - 0.066 13.5 0.0 0.35 11.1 0.0 1.9 1 1 1 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial COX7a PF02238.15 KEG14291.1 - 0.07 13.5 0.7 0.11 12.9 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII SAS-6_N PF16531.5 KEG14292.1 - 1.2e-24 86.7 0.7 1.7e-24 86.2 0.7 1.2 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal RRP36 PF06102.12 KEG14295.1 - 2.6e-33 115.3 11.0 4.1e-33 114.7 11.0 1.3 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 GSP_synth PF03738.14 KEG14295.1 - 0.06 12.5 0.2 0.077 12.1 0.2 1.1 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp COPI_assoc PF08507.10 KEG14296.1 - 7.8e-15 55.1 11.3 1e-14 54.7 11.3 1.2 1 0 0 1 1 1 1 COPI associated protein EF-hand_8 PF13833.6 KEG14297.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Tcf25 PF04910.14 KEG14298.1 - 3.7e-50 171.0 0.0 5.8e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Ndc1_Nup PF09531.10 KEG14298.1 - 3.1 6.4 8.0 5.6 5.5 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fez1 PF06818.15 KEG14299.1 - 0.81 10.1 108.7 0.56 10.6 20.1 6.6 1 1 5 6 6 6 0 Fez1 LMP PF04778.12 KEG14300.1 - 0.031 14.2 0.2 0.034 14.1 0.2 1.1 1 0 0 1 1 1 0 LMP repeated region DUF501 PF04417.12 KEG14300.1 - 0.051 13.4 0.7 0.065 13.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Ank_2 PF12796.7 KEG14301.1 - 8e-29 100.1 0.0 4.2e-15 56.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEG14301.1 - 3.6e-24 82.2 0.0 0.00031 20.9 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KEG14301.1 - 1e-23 83.3 0.2 8.8e-11 42.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEG14301.1 - 1.2e-20 73.3 0.8 8.7e-06 25.9 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEG14301.1 - 1.1e-19 69.9 0.2 0.0019 18.6 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeat CreA PF05981.12 KEG14301.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 CreA protein E1-E2_ATPase PF00122.20 KEG14302.1 - 1e-43 149.0 3.8 2e-42 144.8 1.3 3.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KEG14302.1 - 6e-18 65.9 0.0 8.3e-17 62.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEG14302.1 - 7.2e-11 41.6 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEG14302.1 - 0.00053 19.8 0.1 0.0015 18.3 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IstB_IS21 PF01695.17 KEG14302.1 - 0.072 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NOA36 PF06524.12 KEG14303.1 - 0.067 12.5 17.3 0.2 11.0 17.3 1.7 1 0 0 1 1 1 0 NOA36 protein Ras PF00071.22 KEG14304.1 - 6.1e-24 84.4 0.0 1.2e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEG14304.1 - 4.7e-12 46.2 0.0 6.1e-11 42.6 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SCO1-SenC PF02630.14 KEG14305.1 - 6e-45 152.4 0.0 8.7e-45 151.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KEG14305.1 - 0.0017 18.2 0.0 0.0046 16.9 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KEG14305.1 - 0.0061 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like GRP PF07172.11 KEG14306.1 - 0.055 14.2 9.6 1.3 9.8 0.2 3.0 3 0 0 3 3 3 0 Glycine rich protein family YebO PF13974.6 KEG14307.1 - 0.15 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 YebO-like protein FBPase PF00316.20 KEG14308.1 - 1.6e-60 203.8 0.3 2.8e-60 203.0 0.1 1.4 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain Flg_bb_rod PF00460.20 KEG14308.1 - 0.57 10.2 2.6 0.74 9.8 0.4 2.3 2 0 0 2 2 2 0 Flagella basal body rod protein RRM_1 PF00076.22 KEG14309.1 - 3.1e-11 42.9 0.0 7e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG14309.1 - 2.1e-06 27.3 2.4 0.00014 21.5 0.5 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEG14309.1 - 6.3e-05 22.8 0.5 0.00047 20.0 0.1 2.3 2 1 0 2 2 2 1 Occluded RNA-recognition motif CDC48_2 PF02933.17 KEG14309.1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DUF4523 PF15023.6 KEG14309.1 - 0.096 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) SLED PF12140.8 KEG14309.1 - 0.1 13.1 0.3 0.25 11.9 0.1 1.7 2 0 0 2 2 2 0 SLED domain DUF1411 PF07199.11 KEG14309.1 - 0.31 10.7 2.4 3.5 7.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1411) PolyA_pol PF01743.20 KEG14311.1 - 2.7e-25 89.2 0.0 4.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KEG14311.1 - 1.5e-08 34.2 0.0 4.7e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LRR_6 PF13516.6 KEG14312.1 - 1.1e-05 25.1 0.4 0.62 10.3 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KEG14312.1 - 0.00031 20.4 0.1 0.035 13.9 0.0 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KEG14312.1 - 0.0044 17.4 0.9 0.48 10.9 0.8 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Actin PF00022.19 KEG14314.1 - 6.7e-140 466.3 0.0 4.5e-139 463.6 0.0 1.8 1 1 0 1 1 1 1 Actin Na_H_antiport_3 PF07399.11 KEG14315.1 - 0.21 10.4 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Cytochrom_NNT PF03264.14 KEG14316.1 - 4.6 6.9 13.0 0.31 10.7 6.4 2.5 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region CSN8_PSD8_EIF3K PF10075.9 KEG14318.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GTP_EFTU PF00009.27 KEG14319.1 - 1.4e-27 96.5 0.0 4.1e-27 95.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEG14319.1 - 2.2e-16 59.7 0.0 4.9e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KEG14319.1 - 2.7e-08 33.8 0.0 5.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KEG14319.1 - 1.1e-07 31.6 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KEG14319.1 - 8.6e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KEG14319.1 - 0.00018 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KEG14319.1 - 0.011 15.8 0.1 2.4 8.2 0.0 2.3 1 1 1 2 2 2 0 Dynamin family GTP_EFTU_D2 PF03144.25 KEG14319.1 - 0.012 16.0 0.0 0.041 14.3 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 2 SRPRB PF09439.10 KEG14319.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 KEG14319.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras family EFTUD2 PF16004.5 KEG14319.1 - 4.5 7.9 9.7 17 6.0 9.7 1.8 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Complex1_LYR PF05347.15 KEG14320.1 - 1.6e-13 50.5 0.7 2.3e-13 50.0 0.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KEG14320.1 - 0.00088 19.8 0.1 0.0021 18.6 0.1 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 KEG14320.1 - 0.011 16.4 1.2 0.42 11.4 0.2 2.2 2 0 0 2 2 2 0 Complex1_LYR-like Myc-LZ PF02344.15 KEG14322.1 - 0.0072 16.4 0.7 0.0072 16.4 0.7 5.1 7 0 0 7 7 7 1 Myc leucine zipper domain ATG16 PF08614.11 KEG14322.1 - 0.016 15.5 20.6 0.016 15.5 20.6 3.7 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 KEG14322.1 - 0.018 15.6 5.4 0.018 15.6 5.4 4.5 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 DUF16 PF01519.16 KEG14322.1 - 0.019 15.4 4.3 0.019 15.4 4.3 3.2 1 1 2 3 3 3 0 Protein of unknown function DUF16 CdAMP_rec PF06153.11 KEG14322.1 - 0.1 12.8 0.8 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Cyclic-di-AMP receptor Filament PF00038.21 KEG14322.1 - 1.7 8.1 44.5 0.14 11.7 19.8 2.4 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 KEG14322.1 - 3.6 7.8 24.6 2.8 8.1 6.4 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family RSS_P20 PF11757.8 KEG14322.1 - 7.9 7.0 10.7 0.4 11.1 0.9 2.8 2 1 1 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain DEAD PF00270.29 KEG14324.1 - 1.8e-44 151.6 0.1 3.1e-44 150.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14324.1 - 5.6e-24 84.6 0.0 1.3e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEG14324.1 - 1.7e-15 57.0 0.6 3.8e-15 55.8 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEG14324.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_7 PF03492.15 KEG14324.1 - 0.094 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase CENP-B_dimeris PF09026.10 KEG14324.1 - 0.18 12.2 13.0 0.15 12.4 3.3 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 KEG14324.1 - 2.4 8.0 15.0 0.26 11.1 2.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Formyl_trans_N PF00551.19 KEG14325.1 - 1e-16 61.2 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase CS PF04969.16 KEG14326.1 - 3.3e-06 28.0 1.2 5.5e-06 27.3 1.2 1.4 1 0 0 1 1 1 1 CS domain PAP2 PF01569.21 KEG14329.1 - 5.4e-17 61.8 1.5 5.4e-17 61.8 1.5 2.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KEG14329.1 - 0.012 15.3 5.4 0.012 15.3 5.4 3.3 1 1 2 3 3 3 0 PAP2 superfamily UPF0016 PF01169.19 KEG14329.1 - 1.4 9.3 6.2 42 4.6 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 MCPsignal PF00015.21 KEG14330.1 - 0.0066 16.3 0.5 0.015 15.1 0.5 1.6 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain GP57 PF17594.2 KEG14330.1 - 0.053 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 Actin PF00022.19 KEG14331.1 - 1.5e-116 389.4 0.0 5e-116 387.7 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KEG14331.1 - 0.00068 18.5 0.0 0.038 12.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein ROK PF00480.20 KEG14331.1 - 0.031 13.7 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 ROK family ERG4_ERG24 PF01222.17 KEG14333.1 - 6.1e-126 420.7 5.0 7.1e-126 420.4 5.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KEG14333.1 - 4.6e-11 42.7 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KEG14333.1 - 5.9e-07 29.8 0.1 3.1e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KEG14333.1 - 6.5e-05 23.3 0.5 0.0002 21.7 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.20 KEG14334.1 - 6.6e-05 23.1 16.4 7.9e-05 22.8 16.4 1.1 1 0 0 1 1 1 1 EamA-like transporter family NAD_binding_1 PF00175.21 KEG14335.1 - 3.2e-21 76.0 0.0 4.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEG14335.1 - 3.2e-12 46.7 0.0 5.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Nsp1_C PF05064.13 KEG14336.1 - 4.7e-05 23.2 1.4 6.3e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region GldM_N PF12081.8 KEG14336.1 - 0.0055 16.8 0.3 0.012 15.7 0.3 1.6 1 1 0 1 1 1 1 GldM N-terminal domain CLZ PF16526.5 KEG14336.1 - 0.0075 16.6 10.9 0.016 15.6 0.3 2.6 2 1 1 3 3 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin PF02996.17 KEG14336.1 - 0.029 14.3 1.0 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit 7tm_6 PF02949.20 KEG14336.1 - 0.038 13.1 0.4 0.053 12.6 0.4 1.3 1 1 0 1 1 1 0 7tm Odorant receptor DUF349 PF03993.12 KEG14336.1 - 0.079 13.3 2.2 0.5 10.7 0.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Snapin_Pallidin PF14712.6 KEG14336.1 - 0.083 13.3 4.4 3.3 8.2 0.1 2.5 2 1 1 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.10 KEG14336.1 - 0.11 12.7 1.9 0.17 12.1 1.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Snf7 PF03357.21 KEG14336.1 - 0.21 11.2 6.1 0.2 11.3 2.0 2.0 1 1 1 2 2 2 0 Snf7 DUF3053 PF11254.8 KEG14336.1 - 0.31 10.6 5.9 0.58 9.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) ZapA PF05164.13 KEG14336.1 - 0.37 11.2 3.3 0.35 11.3 0.7 2.0 1 1 1 2 2 2 0 Cell division protein ZapA Fumerase_C PF05683.12 KEG14337.1 - 2.1e-87 291.8 0.0 3.5e-87 291.0 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 KEG14337.1 - 8e-80 268.1 0.0 1.1e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) LRR_6 PF13516.6 KEG14338.1 - 1.4e-17 62.1 0.1 0.28 11.3 0.0 7.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 KEG14338.1 - 1.6e-10 41.0 0.2 0.26 11.8 0.4 5.8 4 3 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG14338.1 - 2.7e-09 36.3 0.0 2.5 9.0 0.1 7.3 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 KEG14338.1 - 9.8e-06 25.2 0.8 3.6 7.4 0.0 5.1 4 2 0 4 4 4 2 Leucine rich repeat zf-RING_2 PF13639.6 KEG14341.1 - 0.0009 19.5 7.3 0.0009 19.5 7.3 2.7 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KEG14341.1 - 0.059 13.6 2.9 0.21 11.8 2.9 2.0 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KEG14341.1 - 0.19 11.4 6.0 0.56 9.9 6.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TMP_2 PF06791.13 KEG14341.1 - 0.24 11.1 2.9 0.4 10.3 1.5 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein RINGv PF12906.7 KEG14341.1 - 0.54 10.4 6.3 2 8.6 6.3 2.1 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KEG14341.1 - 1.3 9.4 5.5 6 7.3 5.5 2.3 1 0 0 1 1 1 0 RING-like domain Cwf_Cwc_15 PF04889.12 KEG14341.1 - 7 6.3 10.9 15 5.2 10.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NIF PF03031.18 KEG14342.1 - 9.4e-30 103.4 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 KEG14342.1 - 0.0019 18.6 0.0 0.035 14.4 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KEG14342.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) WD40 PF00400.32 KEG14343.1 - 2.7e-10 40.7 6.3 0.0052 17.6 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF_A PF03178.15 KEG14343.1 - 0.062 12.6 0.0 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region Ge1_WD40 PF16529.5 KEG14343.1 - 0.085 11.8 0.0 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallophos PF00149.28 KEG14344.1 - 1.5e-20 74.6 0.5 2.9e-20 73.7 0.4 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DEAD PF00270.29 KEG14345.1 - 1.8e-31 109.3 0.1 3.8e-31 108.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14345.1 - 2.6e-18 66.4 0.0 7.9e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG14345.1 - 0.00046 20.2 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KEG14345.1 - 0.0012 17.6 0.0 0.0027 16.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain CAF1C_H4-bd PF12265.8 KEG14346.1 - 4.9e-09 36.3 0.1 2.1e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KEG14346.1 - 0.00015 22.0 0.6 0.89 9.9 0.1 4.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3592 PF12158.8 KEG14346.1 - 0.0096 16.0 0.6 1.9 8.5 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3592) WD40 PF00400.32 KEG14346.1 - 0.01 16.7 15.8 4.1 8.4 0.4 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG14346.1 - 3.9 8.1 5.2 25 5.5 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.25 KEG14347.1 - 7.2e-42 143.6 0.0 1e-40 139.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14347.1 - 3.2e-16 59.4 0.0 4.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEG14347.1 - 3.9e-16 59.1 0.1 7.3e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEG14347.1 - 3e-09 37.0 0.0 7.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KEG14347.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEG14347.1 - 0.11 11.7 0.1 0.69 9.2 0.1 2.0 1 1 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 KEG14347.1 - 0.32 9.9 0.0 0.47 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Rootletin PF15035.6 KEG14349.1 - 0.01 15.9 10.2 0.95 9.5 6.5 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DIT1_PvcA PF05141.12 KEG14349.1 - 0.015 14.7 0.3 0.018 14.6 0.3 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein TSC22 PF01166.18 KEG14349.1 - 0.039 14.3 3.1 0.24 11.7 0.7 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 KEG14349.1 - 0.042 14.5 2.4 0.27 11.9 2.3 2.0 1 1 0 1 1 1 0 Initiation control protein YabA ADIP PF11559.8 KEG14349.1 - 0.052 13.6 0.8 0.052 13.6 0.8 2.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.11 KEG14349.1 - 0.076 12.9 0.2 0.19 11.6 0.2 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF2381 PF09544.10 KEG14349.1 - 0.09 12.3 6.5 0.053 13.1 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) GAIN PF16489.5 KEG14349.1 - 0.13 11.7 0.5 0.15 11.5 0.5 1.2 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain NYD-SP28_assoc PF14775.6 KEG14349.1 - 0.21 11.7 3.5 4.7 7.4 0.3 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain Hemerythrin PF01814.23 KEG14349.1 - 0.27 11.9 4.8 0.22 12.1 2.1 1.9 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF1192 PF06698.11 KEG14349.1 - 0.32 11.1 4.0 15 5.7 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SlyX PF04102.12 KEG14349.1 - 0.77 10.4 4.7 0.75 10.5 0.2 2.5 2 1 0 2 2 2 0 SlyX UPF0242 PF06785.11 KEG14349.1 - 0.85 9.7 5.8 8.5 6.4 5.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TFIIS_C PF01096.18 KEG14350.1 - 1.4e-16 60.0 12.5 2.7e-16 59.1 12.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 KEG14350.1 - 1.6e-13 51.1 0.0 2.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_M PF07500.14 KEG14351.1 - 3.2e-08 34.0 0.1 5.3e-08 33.3 0.1 1.4 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KEG14351.1 - 0.017 14.9 6.3 0.076 12.9 6.3 2.0 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) SLC3A2_N PF16028.5 KEG14351.1 - 0.059 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Lar_restr_allev PF14354.6 KEG14351.1 - 0.093 13.1 2.4 0.19 12.2 2.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar HEAT_2 PF13646.6 KEG14352.1 - 1.5e-09 38.1 3.2 0.00052 20.4 0.0 4.6 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KEG14352.1 - 1.6e-05 24.8 15.5 0.026 14.8 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 KEG14352.1 - 0.0069 16.4 3.2 0.54 10.3 0.0 3.9 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KEG14352.1 - 0.031 13.8 0.4 0.53 9.8 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 KEG14352.1 - 0.04 14.1 0.1 0.92 9.7 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KEG14352.1 - 0.046 14.3 0.3 0.46 11.1 0.1 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region AAA PF00004.29 KEG14353.1 - 1.8e-31 109.3 0.0 1.1e-28 100.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG14353.1 - 1.7e-11 44.8 5.5 4.9e-05 23.8 0.0 4.6 3 2 2 5 5 3 2 AAA ATPase domain NACHT PF05729.12 KEG14353.1 - 2e-11 44.1 1.2 0.042 13.8 0.0 4.5 3 1 1 4 4 4 3 NACHT domain AAA_22 PF13401.6 KEG14353.1 - 1.7e-08 34.8 0.2 0.0057 16.9 0.0 3.7 3 1 1 4 4 3 2 AAA domain AAA_5 PF07728.14 KEG14353.1 - 8.8e-08 32.2 0.0 0.00026 21.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEG14353.1 - 8.5e-07 29.2 0.1 0.002 18.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEG14353.1 - 9e-07 28.8 0.0 0.00038 20.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEG14353.1 - 2.7e-06 27.3 0.1 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 KEG14353.1 - 6.6e-06 25.8 0.0 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KEG14353.1 - 2.9e-05 24.6 0.0 0.3 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KEG14353.1 - 4.5e-05 23.5 0.0 0.00092 19.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEG14353.1 - 0.0003 20.4 0.0 0.018 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KEG14353.1 - 0.00038 21.0 0.3 2.4 8.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter NB-ARC PF00931.22 KEG14353.1 - 0.00041 19.6 0.6 2.5 7.2 0.0 4.2 5 0 0 5 5 5 1 NB-ARC domain T2SSE PF00437.20 KEG14353.1 - 0.00057 19.0 0.0 0.97 8.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 KEG14353.1 - 0.00078 19.0 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 KEG14353.1 - 0.00088 19.6 0.2 2.9 8.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain TIP49 PF06068.13 KEG14353.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 KEG14353.1 - 0.0021 17.8 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEG14353.1 - 0.0024 18.4 0.1 1.2 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEG14353.1 - 0.0024 17.3 1.1 0.12 11.7 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KEG14353.1 - 0.0026 17.7 0.0 0.6 10.0 0.0 3.3 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KEG14353.1 - 0.0026 18.1 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.26 KEG14353.1 - 0.0029 17.3 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATP_bind_1 PF03029.17 KEG14353.1 - 0.0048 16.7 0.5 0.23 11.2 0.0 2.9 4 0 0 4 4 3 1 Conserved hypothetical ATP binding protein PhoH PF02562.16 KEG14353.1 - 0.0077 15.7 0.1 0.16 11.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein RNA12 PF10443.9 KEG14353.1 - 0.016 14.0 0.0 0.078 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein Rad17 PF03215.15 KEG14353.1 - 0.017 15.1 0.0 1.3 8.9 0.0 2.7 2 1 0 2 2 2 0 Rad17 P-loop domain CobU PF02283.16 KEG14353.1 - 0.017 14.7 0.0 0.29 10.7 0.0 2.5 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TsaE PF02367.17 KEG14353.1 - 0.018 15.0 0.0 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KEG14353.1 - 0.019 15.4 0.0 5.5 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEG14353.1 - 0.031 13.4 0.0 1.8 7.7 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 KEG14353.1 - 0.044 13.5 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase RsgA_GTPase PF03193.16 KEG14353.1 - 0.055 13.4 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 KEG14353.1 - 0.078 13.3 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KEG14353.1 - 0.098 12.3 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 KEG14353.1 - 0.099 12.8 0.1 6.2 6.9 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KEG14353.1 - 0.11 12.2 0.0 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_PrkA PF08298.11 KEG14353.1 - 0.11 11.4 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain G-alpha PF00503.20 KEG14353.1 - 0.13 11.4 0.0 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATPase PF06745.13 KEG14353.1 - 0.16 11.3 0.0 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 KaiC Guanylate_kin PF00625.21 KEG14353.1 - 0.16 11.7 0.0 0.68 9.6 0.0 2.0 2 1 0 2 2 2 0 Guanylate kinase cobW PF02492.19 KEG14353.1 - 0.17 11.5 0.1 24 4.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KEG14353.1 - 0.2 10.9 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 KEG14353.1 - 0.21 11.3 0.1 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KEG14353.1 - 0.22 11.4 0.0 11 5.9 0.0 2.8 3 0 0 3 3 3 0 NTPase Phosducin PF02114.16 KEG14354.1 - 8.7e-07 28.1 0.1 1.7e-06 27.2 0.1 1.3 1 1 0 1 1 1 1 Phosducin MRC1 PF09444.10 KEG14354.1 - 0.0093 16.5 0.3 0.0093 16.5 0.3 1.5 2 0 0 2 2 2 1 MRC1-like domain PEX11 PF05648.14 KEG14356.1 - 8.2e-06 25.4 1.2 0.049 13.1 0.1 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Ank_2 PF12796.7 KEG14357.1 - 4.3e-37 126.6 7.4 8.2e-13 48.8 0.3 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG14357.1 - 7.7e-37 125.2 3.6 1.2e-08 35.3 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG14357.1 - 1.5e-29 98.8 2.8 0.00025 21.3 0.1 7.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KEG14357.1 - 3.3e-28 97.4 3.4 1.8e-08 34.5 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEG14357.1 - 3.7e-26 90.4 5.8 2.5e-06 27.7 0.3 7.0 7 0 0 7 7 7 6 Ankyrin repeat TPR_2 PF07719.17 KEG14357.1 - 6.2e-07 29.0 5.0 0.0016 18.4 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14357.1 - 7e-07 28.8 3.3 5.1e-05 22.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14357.1 - 0.00057 20.1 0.4 0.71 10.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14357.1 - 0.001 19.7 0.6 0.34 11.8 0.0 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14357.1 - 0.001 19.1 1.1 0.011 15.9 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14357.1 - 0.013 15.2 0.0 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 KEG14357.1 - 0.042 14.0 0.2 0.13 12.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14357.1 - 0.45 11.1 4.6 1 10.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 KEG14358.1 - 1.1e-05 26.1 9.5 0.027 15.3 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat PARP_regulatory PF01358.18 KEG14359.1 - 1.5e-14 53.7 0.0 1.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit Lig_chan-Glu_bd PF10613.9 KEG14359.1 - 0.0093 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF2313 PF10076.9 KEG14360.1 - 0.068 13.0 0.4 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) DUF4482 PF14818.6 KEG14360.1 - 0.8 10.6 5.8 0.29 12.0 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) ATF7IP_BD PF16788.5 KEG14360.1 - 7.9 6.5 8.6 1.1 9.3 0.7 2.5 2 1 0 2 2 2 0 ATF-interacting protein binding domain DUF2278 PF10042.9 KEG14362.1 - 0.066 13.2 0.4 0.096 12.7 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) IL31 PF15209.6 KEG14362.1 - 0.12 12.1 0.1 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Interleukin 31 gag_pre-integrs PF13976.6 KEG14362.1 - 0.21 11.5 1.0 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 GAG-pre-integrase domain Spectrin PF00435.21 KEG14362.1 - 0.36 11.3 10.6 2.2 8.8 7.7 2.5 2 1 0 2 2 2 0 Spectrin repeat ZapD PF07072.11 KEG14362.1 - 0.41 10.4 6.9 0.78 9.4 0.6 2.3 1 1 1 2 2 2 0 Cell division protein Rootletin PF15035.6 KEG14362.1 - 0.67 9.9 9.0 0.45 10.5 5.0 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Exonuc_VII_L PF02601.15 KEG14362.1 - 0.69 9.4 3.8 0.97 8.9 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SPAM PF02090.15 KEG14362.1 - 1.7 8.5 7.5 7.7 6.3 0.8 2.4 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein zf-Tim10_DDP PF02953.15 KEG14363.1 - 0.0058 16.2 0.7 0.0097 15.5 0.0 1.7 2 1 0 2 2 2 1 Tim10/DDP family zinc finger Pkinase PF00069.25 KEG14364.1 - 2.7e-41 141.7 0.0 7e-41 140.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14364.1 - 6.5e-27 94.4 0.0 2e-19 69.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG14364.1 - 0.008 16.1 3.8 0.024 14.6 0.3 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG14364.1 - 0.013 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KEG14364.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.20 KEG14365.1 - 1.9e-10 41.2 0.0 0.00046 20.7 0.0 3.5 2 1 0 2 2 2 2 Rhodanese-like domain F-box_4 PF15966.5 KEG14366.1 - 0.24 11.3 0.6 0.53 10.2 0.6 1.6 1 0 0 1 1 1 0 F-box AAA_16 PF13191.6 KEG14367.1 - 5.4e-06 26.9 0.1 1.5e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEG14367.1 - 0.0094 16.2 0.0 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2791 PF10923.8 KEG14367.1 - 0.031 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NB-ARC PF00931.22 KEG14367.1 - 0.033 13.4 0.2 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 KEG14367.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KEG14367.1 - 0.053 14.0 0.0 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 KEG14367.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEG14367.1 - 0.23 11.6 1.4 0.54 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain Amastin PF07344.11 KEG14368.1 - 8.9e-52 175.0 16.1 1e-51 174.9 16.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 KEG14368.1 - 0.00033 20.5 6.5 0.00061 19.6 6.5 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF1218 PF06749.12 KEG14368.1 - 1.2 9.7 21.5 1.5 9.4 1.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) SUR7 PF06687.12 KEG14368.1 - 6.9 6.2 23.0 2.5 7.7 12.7 2.6 1 1 1 2 2 2 0 SUR7/PalI family ABC_membrane PF00664.23 KEG14369.1 - 3.4e-119 397.5 25.5 1.3e-65 221.7 11.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEG14369.1 - 8.3e-67 223.9 0.0 1.8e-33 115.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEG14369.1 - 9e-15 54.7 0.1 2.3e-06 27.2 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEG14369.1 - 3.9e-07 30.6 0.8 0.028 14.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KEG14369.1 - 6.8e-07 28.8 0.0 0.0026 17.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KEG14369.1 - 5.3e-06 26.4 0.0 0.16 11.9 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KEG14369.1 - 2.6e-05 24.1 0.0 0.041 13.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEG14369.1 - 4.7e-05 23.7 0.4 0.078 13.3 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 KEG14369.1 - 5.1e-05 23.7 0.1 0.56 10.6 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEG14369.1 - 7.5e-05 22.4 2.0 0.36 10.6 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KEG14369.1 - 0.00013 20.9 0.0 0.077 11.8 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 KEG14369.1 - 0.00017 22.1 0.0 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEG14369.1 - 0.00027 20.9 0.1 0.07 13.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KEG14369.1 - 0.00052 19.7 1.1 0.94 9.1 0.0 2.9 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 KEG14369.1 - 0.00092 19.2 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain G-alpha PF00503.20 KEG14369.1 - 0.0019 17.5 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 KEG14369.1 - 0.0025 17.4 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KEG14369.1 - 0.0043 16.6 0.2 4.5 6.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KEG14369.1 - 0.007 16.6 0.0 2 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KEG14369.1 - 0.0095 15.7 0.0 0.81 9.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 KEG14369.1 - 0.011 15.6 0.0 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KEG14369.1 - 0.013 14.7 0.0 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 KEG14369.1 - 0.017 14.1 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KEG14369.1 - 0.02 15.3 0.0 4.5 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KEG14369.1 - 0.031 14.8 0.0 9.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEG14369.1 - 0.037 13.8 0.1 1.9 8.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KEG14369.1 - 0.058 13.5 0.2 7.2 6.7 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KEG14369.1 - 0.12 12.4 0.0 1.7 8.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 KEG14369.1 - 0.41 10.9 9.2 7.9 6.8 0.8 4.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Myosin_head PF00063.21 KEG14370.1 - 6.8e-230 764.8 0.0 8.5e-230 764.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KEG14370.1 - 3.5e-15 56.2 0.0 2.8e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding WW PF00397.26 KEG14370.1 - 8.6e-08 32.1 1.4 1.9e-07 31.0 1.4 1.6 1 0 0 1 1 1 1 WW domain FYVE PF01363.21 KEG14370.1 - 0.00015 21.8 12.3 0.00032 20.8 12.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 KEG14370.1 - 0.021 15.2 0.0 0.021 15.2 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KEG14370.1 - 0.082 13.4 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DREPP PF05558.12 KEG14370.1 - 1.7 8.5 11.6 77 3.1 0.0 2.3 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide RR_TM4-6 PF06459.12 KEG14370.1 - 2.1 8.1 8.1 3.2 7.5 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 KEG14370.1 - 5.3 6.8 10.5 21 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4515 PF14988.6 KEG14371.1 - 0.018 14.9 13.0 0.15 11.9 0.3 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4515) MbeD_MobD PF04899.12 KEG14371.1 - 0.041 14.0 8.1 5.1 7.3 8.1 3.2 1 1 0 1 1 1 0 MbeD/MobD like DUF4407 PF14362.6 KEG14371.1 - 0.07 12.5 6.8 0.18 11.1 0.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 KEG14371.1 - 0.36 10.6 7.6 2.2 8.0 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) SlyX PF04102.12 KEG14371.1 - 0.43 11.2 16.5 2.2 9.0 0.1 3.7 3 1 0 3 3 3 0 SlyX DUF641 PF04859.12 KEG14371.1 - 0.48 10.8 10.6 0.19 12.0 1.7 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) ERM PF00769.19 KEG14371.1 - 0.57 10.0 17.9 0.05 13.4 11.3 2.4 2 1 0 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 KEG14371.1 - 0.62 10.5 4.7 5.8 7.4 0.1 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 KEG14371.1 - 0.66 10.1 10.3 2.2 8.4 0.2 2.8 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 KEG14371.1 - 1.4 8.3 13.1 1.1 8.7 5.8 2.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KEG14371.1 - 1.6 8.9 17.3 0.65 10.2 0.8 3.0 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KEG14371.1 - 3.8 6.8 14.1 0.66 9.3 0.6 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KEG14371.1 - 4.2 7.2 11.1 16 5.3 0.0 4.2 4 0 0 4 4 4 0 Septum formation initiator DUF3958 PF13125.6 KEG14371.1 - 4.8 7.4 12.2 0.099 12.9 3.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) HEAT PF02985.22 KEG14372.1 - 5.9e-05 23.0 3.6 0.37 11.2 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KEG14372.1 - 9.4e-05 22.7 5.7 0.21 12.0 0.3 3.7 3 1 1 4 4 4 2 HEAT repeats Dynactin PF12455.8 KEG14372.1 - 0.0007 18.9 1.5 0.001 18.4 1.5 1.2 1 0 0 1 1 1 1 Dynein associated protein CDC14 PF08045.11 KEG14372.1 - 0.0052 15.9 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Fes1 PF08609.10 KEG14372.1 - 0.016 16.1 1.0 0.025 15.4 0.2 1.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 tRNA-synt_His PF13393.6 KEG14372.1 - 0.037 13.3 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase HEAT_EZ PF13513.6 KEG14372.1 - 0.062 13.8 5.3 8.2 7.1 0.0 3.5 3 1 0 3 3 3 0 HEAT-like repeat RIX1 PF08167.12 KEG14372.1 - 0.14 11.9 0.9 0.48 10.1 0.9 2.0 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis KIP1 PF07765.12 KEG14372.1 - 0.15 12.2 0.6 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 KIP1-like protein PBP1_TM PF14812.6 KEG14373.1 - 0.0042 17.4 2.4 0.0088 16.4 2.4 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3c_N PF05470.12 KEG14373.1 - 0.11 10.8 0.2 0.16 10.3 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sporozoite_P67 PF05642.11 KEG14373.1 - 0.31 9.1 0.7 0.44 8.6 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen N2227 PF07942.12 KEG14374.1 - 5e-93 311.2 0.0 6.9e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Mito_fiss_reg PF05308.11 KEG14374.1 - 2.8 8.0 7.7 5.1 7.1 7.7 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator EF-hand_7 PF13499.6 KEG14376.1 - 3.8e-12 46.5 0.7 8.5e-11 42.2 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KEG14376.1 - 2e-10 40.4 0.0 2.2e-09 37.0 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KEG14376.1 - 2.1e-09 36.3 0.6 0.00029 20.2 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KEG14376.1 - 1.5e-07 30.7 3.2 0.063 13.2 0.6 3.9 3 1 2 5 5 5 2 EF-hand domain EF-hand_9 PF14658.6 KEG14376.1 - 0.00034 20.9 0.0 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain NAPRTase_C PF17956.1 KEG14376.1 - 0.1 13.0 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain EF-hand_5 PF13202.6 KEG14376.1 - 1.8 8.2 6.3 0.17 11.4 0.7 2.3 2 1 0 2 2 2 0 EF hand UPRTase PF14681.6 KEG14377.1 - 3.4e-71 239.0 0.0 4.3e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEG14377.1 - 1.3e-05 24.7 0.0 2.6e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SET PF00856.28 KEG14378.1 - 4.3e-09 37.0 0.0 3.9e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 KEG14378.1 - 0.0015 18.7 1.1 1.2 9.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14378.1 - 0.0052 16.6 1.6 0.38 10.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14378.1 - 0.043 13.9 0.7 2.3 8.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 KEG14379.1 - 7.7e-39 133.1 0.0 1.4e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KEG14379.1 - 5.6e-38 130.7 0.0 8.3e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 KEG14379.1 - 5.4e-12 45.3 0.1 1.3e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEG14379.1 - 0.0002 21.8 0.2 0.12 12.7 0.1 3.3 3 1 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 KEG14379.1 - 0.0003 20.6 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEG14379.1 - 0.0023 18.1 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KEG14379.1 - 0.0092 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KEG14379.1 - 0.013 15.7 0.0 0.47 10.7 0.0 2.6 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEG14379.1 - 0.03 13.7 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEG14379.1 - 0.042 13.9 0.2 0.21 11.6 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KEG14379.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CPSF_A PF03178.15 KEG14382.1 - 1.8e-48 165.5 0.0 3.4e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region Pkinase PF00069.25 KEG14383.1 - 9.4e-69 231.7 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14383.1 - 2.3e-35 122.1 0.0 3.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14383.1 - 2.8e-07 30.2 0.0 5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like LETM1 PF07766.13 KEG14383.1 - 0.0059 16.0 0.5 0.04 13.3 0.2 2.0 1 1 1 2 2 2 1 LETM1-like protein Haspin_kinase PF12330.8 KEG14383.1 - 0.018 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KEG14383.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEG14383.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KEG14383.1 - 0.082 11.9 1.8 0.19 10.7 1.8 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 POLO_box PF00659.18 KEG14383.1 - 0.14 12.4 0.0 4.4 7.6 0.0 2.9 2 0 0 2 2 2 0 POLO box duplicated region DUF3808 PF10300.9 KEG14386.1 - 2.3e-24 86.0 0.5 8.1e-24 84.2 0.4 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KEG14386.1 - 2e-07 31.2 8.1 0.044 14.1 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEG14386.1 - 7.5e-05 22.1 0.6 0.00026 20.3 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14386.1 - 0.00016 21.5 15.2 0.22 11.7 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF2225 PF09986.9 KEG14386.1 - 0.0012 18.7 3.8 0.043 13.5 0.3 2.9 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 KEG14386.1 - 0.0012 19.1 5.7 1.6 9.0 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KEG14386.1 - 0.0018 17.7 1.4 1.2 8.4 0.0 3.2 1 1 3 4 4 4 1 MalT-like TPR region Egg_lysin PF01303.17 KEG14386.1 - 0.0097 16.1 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 Egg lysin (Sperm-lysin) TPR_16 PF13432.6 KEG14386.1 - 0.033 14.8 5.1 13 6.5 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14386.1 - 0.053 13.4 6.5 9 6.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KEG14386.1 - 0.057 13.3 0.8 0.18 11.7 0.0 2.3 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_8 PF13181.6 KEG14386.1 - 0.061 13.6 3.7 62 4.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG14386.1 - 0.73 10.6 9.6 11 6.9 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1515 PF07439.11 KEG14387.1 - 0.02 14.9 5.5 6.6 6.8 0.0 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1515) PKcGMP_CC PF16808.5 KEG14387.1 - 0.031 14.1 3.9 0.031 14.1 3.9 4.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase T3SchapCesA PF11439.8 KEG14387.1 - 0.058 13.5 9.9 0.54 10.4 1.4 3.9 3 1 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF1664 PF07889.12 KEG14387.1 - 0.6 10.2 20.9 0.28 11.2 4.7 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) Nas2_N PF18265.1 KEG14387.1 - 3.7 7.5 8.4 5.6 7.0 0.0 4.9 3 2 1 4 4 4 0 Nas2 N_terminal domain SnoaL_2 PF12680.7 KEG14388.1 - 0.0042 17.7 0.4 0.022 15.4 0.4 2.1 1 1 0 1 1 1 1 SnoaL-like domain ATP-synt_C PF00137.21 KEG14389.1 - 2.6e-19 69.3 38.2 2.9e-11 43.5 13.7 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Ribosomal_L15e PF00827.17 KEG14390.1 - 3.3e-83 278.1 8.9 3.8e-83 277.9 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L5e PF17144.4 KEG14391.1 - 7.4e-94 312.2 2.3 3.1e-75 251.7 0.3 2.4 2 0 0 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KEG14391.1 - 3.9e-26 91.8 5.0 3.9e-26 91.8 5.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DivIC PF04977.15 KEG14392.1 - 0.019 14.7 0.2 0.035 13.9 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator EMP24_GP25L PF01105.24 KEG14393.1 - 2.1e-42 145.1 0.0 2.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 7TM_GPCR_Srsx PF10320.9 KEG14394.1 - 0.047 13.1 0.3 0.054 12.9 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Acyl_transf_3 PF01757.22 KEG14394.1 - 0.055 12.5 1.7 0.068 12.2 1.7 1.1 1 0 0 1 1 1 0 Acyltransferase family Lysine_decarbox PF03641.14 KEG14395.1 - 0.027 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Possible lysine decarboxylase Ebp2 PF05890.12 KEG14396.1 - 8e-41 140.4 15.8 1.8e-40 139.2 15.8 1.6 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 HGD-D PF06050.13 KEG14396.1 - 0.14 11.9 1.1 0.19 11.5 1.1 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component ARGLU PF15346.6 KEG14396.1 - 9.2 6.1 22.1 1.2 9.0 13.6 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 GAS PF13851.6 KEG14397.1 - 1.4e-58 197.6 22.6 1.4e-58 197.6 22.6 2.5 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Propep_M14 PF02244.16 KEG14397.1 - 2.9 8.4 6.9 27 5.3 0.5 4.0 3 1 0 3 3 3 0 Carboxypeptidase activation peptide DTW PF03942.15 KEG14398.1 - 2.5e-22 79.5 0.0 4.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 KEG14398.1 - 0.15 12.2 0.8 0.28 11.4 0.8 1.5 1 0 0 1 1 1 0 B-box zinc finger zinc_ribbon_9 PF14369.6 KEG14398.1 - 0.27 11.5 4.4 0.51 10.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon DNA_pol_E_B PF04042.16 KEG14399.1 - 7.8e-29 100.5 0.1 1.2e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B EF-hand_like PF09279.11 KEG14402.1 - 0.015 15.8 2.5 0.048 14.1 2.4 1.9 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like NUC PF18510.1 KEG14402.1 - 0.14 12.5 4.4 0.21 12.0 4.4 1.2 1 0 0 1 1 1 0 Nuclease domain DUF148 PF02520.17 KEG14402.1 - 2.2 8.4 13.4 2.2 8.4 3.7 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 PRP1_N PF06424.12 KEG14402.1 - 3.1 8.2 7.3 4.2 7.8 7.3 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal YabA PF06156.13 KEG14402.1 - 3.4 8.3 12.0 1.3 9.7 2.3 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Proteasom_Rpn13 PF04683.13 KEG14403.1 - 2.5e-14 53.5 0.1 3.8e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KEG14403.1 - 3.3e-10 40.1 0.0 4.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 UCH-binding domain cNMP_binding PF00027.29 KEG14406.1 - 1.3e-18 66.8 0.0 1e-08 35.1 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain YpjP PF14005.6 KEG14407.1 - 0.16 12.1 5.1 0.13 12.3 3.0 1.8 1 1 1 2 2 2 0 YpjP-like protein DUF3818 PF12825.7 KEG14407.1 - 2.7 6.9 9.6 3.8 6.4 9.6 1.3 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) O-antigen_lig PF13425.6 KEG14407.1 - 6.8 5.3 4.6 6.9 5.3 4.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein EF-hand_7 PF13499.6 KEG14407.1 - 8.6 6.9 8.1 44 4.6 0.5 3.3 2 1 1 3 3 3 0 EF-hand domain pair SseB PF07179.12 KEG14408.1 - 0.014 15.7 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 SseB protein N-terminal domain SR-25 PF10500.9 KEG14408.1 - 0.65 9.6 13.1 0.28 10.8 2.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_zinc_N_2 PF13602.6 KEG14409.1 - 1.9e-14 54.8 0.1 5.1e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEG14409.1 - 3e-12 46.4 1.4 1.9e-11 43.8 0.1 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEG14409.1 - 9.6e-12 45.0 0.1 1.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HALZ PF02183.18 KEG14411.1 - 0.003 17.7 2.4 0.011 15.9 0.1 2.9 1 1 1 2 2 2 1 Homeobox associated leucine zipper OmpH PF03938.14 KEG14411.1 - 0.0075 16.6 6.6 0.0075 16.6 6.6 3.2 3 1 0 3 3 3 1 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 KEG14411.1 - 0.092 12.9 9.6 0.17 12.0 0.1 4.3 2 1 1 3 3 3 0 bZIP transcription factor CorA PF01544.18 KEG14411.1 - 0.1 11.9 16.9 0.96 8.7 6.2 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TINF2_N PF14973.6 KEG14411.1 - 0.41 11.0 7.5 0.25 11.7 2.3 2.6 2 1 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Gal4_dimer PF03902.13 KEG14411.1 - 0.57 10.4 5.8 19 5.5 0.2 3.7 3 0 0 3 3 3 0 Gal4-like dimerisation domain V_ATPase_I PF01496.19 KEG14411.1 - 0.65 7.8 19.3 0.12 10.3 5.7 2.4 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2533 PF10752.9 KEG14411.1 - 0.75 10.3 5.3 0.47 10.9 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Atg14 PF10186.9 KEG14411.1 - 1.1 8.3 16.6 1.1 8.3 3.7 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KEG14411.1 - 1.2 7.0 11.1 0.35 8.8 2.6 2.2 2 0 0 2 2 2 0 Prominin Golgin_A5 PF09787.9 KEG14411.1 - 2 7.8 26.2 0.14 11.6 5.5 2.9 3 0 0 3 3 3 0 Golgin subfamily A member 5 Lectin_N PF03954.14 KEG14411.1 - 3.7 7.3 12.0 0.29 10.9 4.2 2.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF3037 PF11236.8 KEG14411.1 - 4.9 7.6 12.1 8.9 6.8 0.9 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF3037) FlaC_arch PF05377.11 KEG14411.1 - 6.4 7.3 14.3 7 7.1 0.1 4.9 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) COG5 PF10392.9 KEG14411.1 - 7.3 6.8 18.4 0.24 11.6 1.6 3.9 3 2 2 5 5 4 0 Golgi transport complex subunit 5 GIT1_C PF12205.8 KEG14411.1 - 7.4 6.7 9.1 0.52 10.4 1.0 2.8 2 2 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term MSA-2c PF12238.8 KEG14412.1 - 0.03 14.3 1.3 0.087 12.8 1.3 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c Kinesin PF00225.23 KEG14414.1 - 3e-86 289.4 1.1 1.1e-85 287.5 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG14414.1 - 3.9e-13 49.6 3.8 4.4e-13 49.4 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding DUF2206 PF09971.9 KEG14415.1 - 0.7 8.6 2.7 1 8.0 2.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) FGE-sulfatase PF03781.16 KEG14416.1 - 3e-19 69.6 1.3 6.1e-19 68.6 1.3 1.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KEG14416.1 - 3.4e-09 37.3 0.0 7.8e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.6 KEG14416.1 - 3.4e-07 30.9 0.3 0.049 14.3 0.0 3.6 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 KEG14416.1 - 0.00012 21.9 0.0 0.078 12.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KEG14416.1 - 0.00027 20.8 0.0 0.00079 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG14416.1 - 0.0009 20.0 0.0 0.047 14.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG14416.1 - 0.0039 17.8 0.0 0.35 11.5 0.0 2.9 1 1 0 1 1 1 1 Methyltransferase domain ABC2_membrane PF01061.24 KEG14418.1 - 8.1e-11 41.7 14.0 1.4e-10 40.9 14.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KEG14418.1 - 0.00064 20.3 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF2070 PF09843.9 KEG14418.1 - 1.3 7.2 8.4 1.9 6.7 8.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LETM1 PF07766.13 KEG14419.1 - 2.8e-60 203.9 0.0 7.3e-60 202.6 0.0 1.6 2 0 0 2 2 2 1 LETM1-like protein Peptidase_A22B PF04258.13 KEG14420.1 - 2.5e-61 207.7 17.6 1.4e-55 188.9 10.4 2.1 1 1 1 2 2 2 2 Signal peptide peptidase SPP PF06550.11 KEG14420.1 - 0.00029 20.4 21.5 0.0019 17.7 21.5 2.1 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease IPPT PF01715.17 KEG14421.1 - 1.4e-44 152.6 0.0 7.4e-38 130.6 0.0 2.1 2 0 0 2 2 2 2 IPP transferase IPT PF01745.16 KEG14421.1 - 8e-06 25.4 0.0 0.019 14.4 0.0 3.1 3 0 0 3 3 3 2 Isopentenyl transferase DUF2075 PF09848.9 KEG14421.1 - 0.0039 16.5 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KEG14421.1 - 0.0042 16.6 0.0 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein CbiA PF01656.23 KEG14421.1 - 0.0089 16.1 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KEG14421.1 - 0.021 15.1 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEG14421.1 - 0.024 14.8 0.2 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 KEG14421.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) SWI2_SNF2 PF18766.1 KEG14421.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ResIII PF04851.15 KEG14421.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KEG14421.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FeoB_associated PF12669.7 KEG14422.1 - 0.0042 17.5 0.3 0.0042 17.5 0.3 2.4 2 1 0 2 2 2 1 FeoB-associated Cys-rich membrane protein RVT_1 PF00078.27 KEG14423.1 - 6.4e-16 58.5 0.0 7.3e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KEG14426.1 - 5.1e-11 42.2 0.0 7.6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEG14426.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gp58 PF07902.11 KEG14428.1 - 0.011 14.1 2.0 0.017 13.5 2.0 1.3 1 0 0 1 1 1 0 gp58-like protein KH_1 PF00013.29 KEG14428.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 KH domain Cas_Csa4 PF09703.10 KEG14428.1 - 0.073 12.4 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) FapA PF03961.13 KEG14428.1 - 0.099 11.2 2.6 0.11 11.1 1.0 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Flavi_DEAD PF07652.14 KEG14428.1 - 0.11 12.5 0.6 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Flavivirus DEAD domain DUF4407 PF14362.6 KEG14428.1 - 0.22 10.8 6.6 1.1 8.6 6.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KEG14428.1 - 0.25 11.6 5.5 0.4 10.9 0.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 KEG14428.1 - 0.26 11.8 1.5 2 8.9 0.1 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 KEG14428.1 - 0.58 10.4 4.3 0.33 11.2 0.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 KEG14428.1 - 1.7 9.0 12.5 0.21 11.9 0.6 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Spc7 PF08317.11 KEG14428.1 - 2 7.2 11.2 0.29 10.0 2.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 KEG14428.1 - 2.2 9.3 6.7 3.1 8.8 2.4 2.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4140 PF13600.6 KEG14428.1 - 2.4 8.7 11.9 7.9 7.0 0.9 3.9 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF3535 PF12054.8 KEG14428.1 - 3.4 6.8 9.2 1.2 8.3 1.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3535) BRE1 PF08647.11 KEG14428.1 - 4.1 7.5 8.0 12 6.1 3.0 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 KEG14428.1 - 10 6.8 11.3 15 6.3 2.1 2.5 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPH PF13868.6 KEG14429.1 - 5.4e-40 137.0 131.0 5.4e-40 137.0 131.0 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Ribosomal_L24e PF01246.20 KEG14430.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L24e TRAP_beta PF05753.14 KEG14431.1 - 3.8e-15 55.7 2.9 2.4e-14 53.1 2.9 2.2 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 KEG14431.1 - 1.7e-09 37.9 4.6 3.6e-09 36.8 4.6 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 KEG14431.1 - 3.7e-08 33.5 0.4 5.7e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.9 KEG14431.1 - 0.013 15.7 0.3 0.03 14.6 0.3 1.6 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ASH PF15780.5 KEG14431.1 - 0.063 13.5 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin tRNA-synt_1 PF00133.22 KEG14433.1 - 5.7e-187 622.6 0.0 6.1e-186 619.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEG14433.1 - 2.1e-35 121.9 0.0 3.7e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 KEG14433.1 - 1.3e-14 54.2 2.8 1.3e-14 54.2 2.8 2.0 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 KEG14433.1 - 1.4e-14 53.7 0.2 3.4e-07 29.4 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KEG14433.1 - 1.2e-05 24.9 0.1 0.035 13.6 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 ABC_tran_CTD PF16326.5 KEG14433.1 - 0.018 15.3 0.5 0.041 14.1 0.5 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain tRNA-synt_1b PF00579.25 KEG14433.1 - 0.082 12.2 0.2 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CIDE-N PF02017.15 KEG14433.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 CIDE-N domain Jag_N PF14804.6 KEG14433.1 - 0.2 12.0 0.6 0.64 10.4 0.6 1.9 1 0 0 1 1 1 0 Jag N-terminus SAM_decarbox PF01536.16 KEG14434.1 - 7.2e-14 51.6 0.0 9.2e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase SAM_decarbox PF01536.16 KEG14435.1 - 1e-85 287.9 0.0 1.2e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PPR_3 PF13812.6 KEG14436.1 - 0.018 15.1 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain RRM_1 PF00076.22 KEG14437.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_N PF00288.26 KEG14438.1 - 1.2e-12 47.8 0.1 3.1e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEG14438.1 - 5e-10 39.6 0.1 1e-09 38.6 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Cytomega_gL PF01801.16 KEG14438.1 - 0.081 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L tRNA_m1G_MT PF01746.21 KEG14440.1 - 3.4e-18 66.1 0.0 6.3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Kinesin PF00225.23 KEG14441.1 - 9.2e-80 268.1 0.0 9.2e-80 268.1 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG14441.1 - 3.2e-21 75.8 1.4 1.8e-20 73.4 0.1 2.5 2 0 0 2 2 2 1 Microtubule binding VGPC1_C PF16799.5 KEG14441.1 - 0.02 14.9 2.2 8.3 6.5 0.5 3.4 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HIRAN PF08797.11 KEG14441.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 HIRAN domain AAA_16 PF13191.6 KEG14441.1 - 2.6 8.4 0.0 2.6 8.4 0.0 4.0 3 1 1 4 4 4 0 AAA ATPase domain Pkinase PF00069.25 KEG14442.1 - 1.5e-64 217.9 0.0 3.5e-64 216.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14442.1 - 5e-47 160.4 0.0 8e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG14442.1 - 0.0058 15.5 0.0 0.0095 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase MINDY_DUB PF04424.13 KEG14443.1 - 2.2e-17 63.2 0.0 5.1e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase eIF-3_zeta PF05091.12 KEG14444.1 - 2e-77 261.4 2.3 2.8e-75 254.3 1.5 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cu-oxidase_2 PF07731.14 KEG14444.1 - 0.058 13.1 0.1 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Multicopper oxidase Fer2_3 PF13085.6 KEG14446.1 - 7e-31 106.5 0.1 1.2e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 KEG14446.1 - 0.024 14.6 1.1 0.024 14.6 1.1 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Mog1 PF04603.12 KEG14447.1 - 7.9e-36 123.5 0.0 9.7e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ezh2_MCSS PF18600.1 KEG14447.1 - 0.12 12.1 1.1 1 9.1 0.0 2.2 2 0 0 2 2 2 0 MCSS domain GvpO PF05800.11 KEG14447.1 - 0.15 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO DUF805 PF05656.14 KEG14448.1 - 0.64 10.4 5.9 13 6.3 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) CBP_BcsF PF11120.8 KEG14448.1 - 0.73 10.0 14.0 2.1 8.5 4.0 2.8 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF DEAD PF00270.29 KEG14449.1 - 1.4e-13 51.0 0.0 3.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14449.1 - 1.9e-09 37.8 0.0 3.3e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HxlR PF01638.17 KEG14449.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HHH_5 PF14520.6 KEG14449.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4332 PF14229.6 KEG14449.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Mito_carr PF00153.27 KEG14451.1 - 3e-39 132.8 0.9 3.6e-18 65.3 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein MacB_PCD PF12704.7 KEG14452.1 - 0.026 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 MacB-like periplasmic core domain Ead_Ea22 PF13935.6 KEG14452.1 - 8.7 7.0 9.9 7.5 7.2 4.3 2.6 2 1 0 2 2 2 0 Ead/Ea22-like protein Radical_SAM_C PF16199.5 KEG14453.1 - 1.5e-17 63.4 0.4 3.1e-17 62.4 0.4 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KEG14453.1 - 3.2e-14 53.7 0.1 1.2e-13 51.8 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KEG14453.1 - 4.1e-08 33.5 0.2 1.7e-07 31.4 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG14453.1 - 0.00025 21.0 0.1 0.00054 19.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEG14453.1 - 0.0071 16.7 0.1 0.021 15.3 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain VIR_N PF15912.5 KEG14453.1 - 0.15 11.6 2.4 0.23 11.0 2.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Mito_fiss_reg PF05308.11 KEG14453.1 - 3.1 7.8 5.7 4.6 7.2 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KEG14453.1 - 3.5 7.0 12.0 5.7 6.3 12.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KEG14453.1 - 7.7 6.6 12.4 14 5.7 12.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Tail_P2_I PF09684.10 KEG14454.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) US2 PF02476.15 KEG14454.1 - 0.16 12.7 0.0 3.4 8.4 0.0 2.5 2 0 0 2 2 2 0 US2 family DNA_pol_B PF00136.21 KEG14455.1 - 1.5e-83 281.0 0.0 2e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEG14455.1 - 7.6e-14 51.6 0.0 3.6e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KEG14455.1 - 0.00017 22.0 7.1 0.00046 20.6 7.1 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF2933 PF11666.8 KEG14455.1 - 0.23 11.5 1.2 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) BDHCT_assoc PF16204.5 KEG14455.1 - 4.7 6.8 5.6 11 5.6 5.6 1.5 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Lactamase_B_2 PF12706.7 KEG14456.1 - 5.2e-14 52.2 0.1 3.1e-13 49.7 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEG14456.1 - 0.0031 17.5 1.0 0.0038 17.3 0.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily 4HBT_3 PF13622.6 KEG14457.1 - 0.00075 19.8 0.5 0.0012 19.2 0.5 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KEG14457.1 - 0.0055 17.0 0.6 0.012 16.0 0.6 1.6 1 0 0 1 1 1 1 Thioesterase superfamily YceI PF04264.13 KEG14458.1 - 2.3e-05 25.0 0.0 3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain Peptidase_C32 PF05411.12 KEG14458.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase AAA_6 PF12774.7 KEG14459.1 - 5.7e-150 498.8 0.0 9.4e-149 494.8 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KEG14459.1 - 2.7e-144 481.9 0.0 2.7e-144 481.9 0.0 4.2 5 0 0 5 5 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KEG14459.1 - 2.2e-109 366.2 8.9 2.2e-109 366.2 8.9 5.2 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG14459.1 - 3.3e-104 347.8 0.0 1.4e-103 345.8 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KEG14459.1 - 1.9e-85 286.8 2.3 1.5e-84 283.8 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KEG14459.1 - 3.4e-78 261.8 3.4 3.4e-78 261.8 3.4 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KEG14459.1 - 3.2e-69 232.1 1.0 5.6e-62 208.5 0.0 3.8 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG14459.1 - 9.9e-56 188.1 3.4 1.2e-54 184.6 0.2 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG14459.1 - 3e-44 149.9 0.0 5.1e-42 142.7 0.0 4.0 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KEG14459.1 - 2.7e-41 141.8 13.8 2.7e-41 141.8 13.8 1.7 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KEG14459.1 - 3.8e-25 88.5 0.3 3.3e-10 40.1 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KEG14459.1 - 7.1e-22 77.9 0.1 4.7e-21 75.2 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KEG14459.1 - 2.7e-17 62.8 0.0 1.2e-16 60.7 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KEG14459.1 - 9.2e-08 32.6 0.2 0.19 12.1 0.0 5.3 6 0 0 6 6 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG14459.1 - 9.3e-08 32.4 0.5 0.14 12.4 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KEG14459.1 - 4.2e-07 30.5 1.4 0.55 10.6 0.0 6.1 5 0 0 5 5 5 1 AAA ATPase domain Sigma54_activat PF00158.26 KEG14459.1 - 3.3e-05 23.6 0.0 0.023 14.4 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 KEG14459.1 - 0.00018 20.7 3.8 0.53 9.3 0.0 4.7 6 0 0 6 6 6 2 Type II/IV secretion system protein RNA_helicase PF00910.22 KEG14459.1 - 0.0006 20.2 0.1 2.4 8.6 0.0 4.0 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 KEG14459.1 - 0.0067 15.8 0.0 3.7 6.9 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEG14459.1 - 0.0071 16.5 0.6 11 6.2 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KEG14459.1 - 0.042 14.4 3.5 13 6.3 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 KEG14459.1 - 0.052 13.3 2.0 12 5.6 0.0 4.2 5 0 0 5 5 4 0 AAA domain Roc PF08477.13 KEG14459.1 - 0.058 13.6 3.0 0.27 11.4 0.3 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Microtub_bd PF16796.5 KEG14459.1 - 0.13 12.2 2.1 7.2 6.5 0.0 3.6 3 0 0 3 3 2 0 Microtubule binding TsaE PF02367.17 KEG14459.1 - 0.31 11.0 6.5 5.1 7.1 0.0 4.3 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KEG14459.1 - 0.4 11.2 7.5 10 6.6 0.0 4.4 4 0 0 4 4 3 0 ABC transporter NACHT PF05729.12 KEG14459.1 - 1.6 8.6 6.5 14 5.6 0.0 4.2 4 0 0 4 4 3 0 NACHT domain PhoH PF02562.16 KEG14459.1 - 2 7.8 7.8 8.6 5.8 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein FA_hydroxylase PF04116.13 KEG14460.1 - 8.9e-23 81.1 23.4 8.9e-23 81.1 23.4 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF4534 PF15049.6 KEG14461.1 - 0.9 9.3 4.1 1.4 8.7 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Pkinase PF00069.25 KEG14462.1 - 1.5e-34 119.6 0.0 1.9e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14462.1 - 3.2e-17 62.7 0.0 5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pirin_C_2 PF17954.1 KEG14462.1 - 0.0068 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Pkinase PF00069.25 KEG14464.1 - 2.1e-07 30.6 0.0 3.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14464.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14464.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Adap_comp_sub PF00928.21 KEG14465.1 - 1.1e-80 270.8 0.0 1.2e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family AAA_6 PF12774.7 KEG14468.1 - 3e-129 430.7 0.0 1.1e-126 422.2 0.0 3.1 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG14468.1 - 2.7e-88 296.8 0.2 1.6e-87 294.2 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KEG14468.1 - 1.3e-57 194.5 0.0 6.9e-57 192.1 0.0 2.4 3 0 0 3 3 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 KEG14468.1 - 3.7e-56 190.3 0.2 3e-38 131.6 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KEG14468.1 - 4.5e-46 156.6 0.0 8.2e-37 126.5 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 KEG14468.1 - 4.8e-32 111.3 1.9 4.8e-32 111.3 1.9 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KEG14468.1 - 2.2e-24 86.1 0.0 6.3e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KEG14468.1 - 5.9e-24 84.6 0.1 9.3e-11 41.9 0.0 6.8 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_C PF18199.1 KEG14468.1 - 6.4e-23 81.4 0.2 6.4e-23 81.4 0.2 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 KEG14468.1 - 2.2e-19 69.7 0.0 1.8e-18 66.7 0.0 2.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 KEG14468.1 - 5.8e-18 65.6 0.0 0.00055 20.4 0.0 5.4 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG14468.1 - 1.3e-12 48.1 2.3 0.0057 16.9 0.0 7.2 7 0 0 7 7 6 3 AAA domain AAA_16 PF13191.6 KEG14468.1 - 3.3e-10 40.6 20.7 0.0064 16.9 0.0 8.4 8 0 0 8 8 6 4 AAA ATPase domain AAA_33 PF13671.6 KEG14468.1 - 6.3e-09 36.1 0.2 1.7 8.8 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KEG14468.1 - 2e-07 31.6 0.4 0.84 10.2 0.0 5.5 5 0 0 5 5 4 1 AAA domain AAA_25 PF13481.6 KEG14468.1 - 3.3e-07 30.1 0.5 0.018 14.6 0.0 5.4 5 0 0 5 5 5 1 AAA domain Sigma54_activat PF00158.26 KEG14468.1 - 6.8e-07 29.1 0.0 0.11 12.1 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KEG14468.1 - 2.4e-06 27.4 0.0 0.063 13.0 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 KEG14468.1 - 5.5e-06 26.2 0.0 5.4 6.7 0.0 4.5 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 KEG14468.1 - 1.5e-05 24.2 0.0 0.83 8.7 0.0 4.1 4 0 0 4 4 4 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KEG14468.1 - 8.9e-05 22.0 7.1 0.37 10.1 0.0 4.4 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI Dynein_AAA_lid PF17852.1 KEG14468.1 - 0.00021 21.4 0.0 0.001 19.1 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RNA_helicase PF00910.22 KEG14468.1 - 0.00082 19.7 0.0 11 6.4 0.0 4.6 4 0 0 4 4 4 0 RNA helicase NACHT PF05729.12 KEG14468.1 - 0.0028 17.6 3.9 0.88 9.5 0.0 4.8 4 0 0 4 4 4 1 NACHT domain Zeta_toxin PF06414.12 KEG14468.1 - 0.0053 16.1 0.2 34 3.6 0.0 4.9 5 0 0 5 5 5 0 Zeta toxin AAA_lid_1 PF17857.1 KEG14468.1 - 0.007 16.6 0.0 0.039 14.2 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEG14468.1 - 0.0079 16.0 0.1 0.51 10.1 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KEG14468.1 - 0.018 15.0 0.5 25 4.9 0.0 4.1 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KEG14468.1 - 0.021 14.6 1.6 38 4.1 0.0 4.0 4 0 0 4 4 4 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEG14468.1 - 0.034 14.7 7.3 28 5.2 0.0 5.1 5 0 0 5 5 4 0 ABC transporter AAA_11 PF13086.6 KEG14468.1 - 0.036 13.8 0.0 0.036 13.8 0.0 4.7 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 KEG14468.1 - 0.081 13.3 8.2 3.9 7.8 0.0 5.2 5 0 0 5 5 4 0 AAA domain cobW PF02492.19 KEG14468.1 - 0.14 11.7 1.8 0.85 9.2 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M8 PF01457.16 KEG14470.1 - 1.6e-137 459.4 0.0 2.2e-137 458.9 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Reprolysin_5 PF13688.6 KEG14470.1 - 0.01 16.0 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3810 PF12725.7 KEG14470.1 - 0.19 11.0 0.2 0.33 10.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CRAL_TRIO PF00650.20 KEG14471.1 - 2e-14 53.6 0.0 3.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF382 PF04037.13 KEG14471.1 - 0.13 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF382) MBOAT_2 PF13813.6 KEG14472.1 - 0.0012 19.0 0.5 0.0023 18.2 0.5 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LSM PF01423.22 KEG14474.1 - 4.7e-12 45.4 0.2 5.9e-12 45.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 KEG14474.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) zf-C2H2_4 PF13894.6 KEG14475.1 - 1.7e-06 28.3 26.2 0.033 15.0 0.1 6.1 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEG14475.1 - 2.5e-05 24.5 13.5 0.054 13.8 1.5 4.6 2 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) DUF3421 PF11901.8 KEG14475.1 - 0.0052 16.8 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3421) zf_UBZ PF18439.1 KEG14475.1 - 0.058 13.0 9.0 5.9 6.6 0.0 4.8 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf_Hakai PF18408.1 KEG14475.1 - 0.079 12.7 1.2 2.9 7.7 0.0 2.8 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 KEG14475.1 - 0.14 12.2 0.2 0.14 12.2 0.2 3.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 KEG14475.1 - 0.39 11.2 0.2 0.39 11.2 0.2 3.0 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KEG14475.1 - 0.84 10.2 31.7 0.23 12.0 0.4 6.6 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KEG14475.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.9 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KEG14475.1 - 3.5 8.2 15.8 5 7.7 0.1 6.0 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_9 PF16293.5 KEG14475.1 - 6.2 6.7 13.3 0.57 10.1 0.2 4.0 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Carn_acyltransf PF00755.20 KEG14478.1 - 2.5e-09 36.3 0.0 3.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNB PF00773.19 KEG14479.1 - 1.6e-96 323.5 0.0 2.5e-96 322.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KEG14479.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KEG14479.1 - 0.095 12.7 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) Mucin PF01456.17 KEG14483.1 - 0.073 13.1 24.8 0.19 11.7 4.7 3.2 2 2 0 2 2 2 0 Mucin-like glycoprotein TFIIA PF03153.13 KEG14483.1 - 0.84 9.6 19.3 1.2 9.1 19.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRT10 PF08728.10 KEG14483.1 - 5.5 5.0 9.3 7.5 4.6 9.3 1.2 1 0 0 1 1 1 0 CRT10 Asp-B-Hydro_N PF05279.11 KEG14483.1 - 8.5 6.4 43.9 1.4 8.9 34.9 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Mucin PF01456.17 KEG14484.1 - 0.00017 21.6 3.4 0.00017 21.6 3.4 3.0 2 1 0 2 2 2 1 Mucin-like glycoprotein Baculo_PEP_C PF04513.12 KEG14484.1 - 0.56 10.2 7.5 0.42 10.6 1.0 3.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GREB1 PF15782.5 KEG14484.1 - 3.1 4.8 13.1 3.4 4.7 13.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Baculo_F PF12259.8 KEG14484.1 - 3.6 6.0 9.5 0.24 9.9 4.5 1.5 2 0 0 2 2 2 0 Baculovirus F protein SKA1 PF07160.12 KEG14484.1 - 7.9 6.2 26.2 1.9 8.2 0.1 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4776 PF16003.5 KEG14484.1 - 8.7 5.2 29.8 17 4.3 29.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) Prenyltrans PF00432.21 KEG14485.1 - 5.8e-14 51.5 10.0 2.8e-09 36.5 0.1 5.4 5 1 0 5 5 5 2 Prenyltransferase and squalene oxidase repeat zf-piccolo PF05715.13 KEG14485.1 - 0.22 11.7 3.4 0.51 10.5 0.3 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger FYVE_2 PF02318.16 KEG14485.1 - 1.1 9.5 3.3 0.38 11.0 0.2 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger Carb_anhydrase PF00194.21 KEG14487.1 - 3.6e-31 108.6 0.0 5.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TPR_2 PF07719.17 KEG14489.1 - 1.3e-11 43.6 2.4 1.1e-05 25.2 0.1 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14489.1 - 3.6e-09 36.0 0.2 3.7e-05 23.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14489.1 - 7.4e-08 32.0 0.3 0.00086 19.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14489.1 - 2.1e-06 28.3 1.5 0.039 14.6 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14489.1 - 2.3e-05 24.0 0.7 0.0015 18.2 0.3 2.6 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KEG14489.1 - 3.7e-05 23.4 0.7 0.048 13.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14489.1 - 8.6e-05 22.8 0.7 0.11 12.9 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14489.1 - 0.0011 19.6 0.1 0.089 13.7 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14489.1 - 0.0019 18.6 0.7 0.11 13.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-MYND PF01753.18 KEG14489.1 - 0.0032 17.5 3.5 0.0089 16.1 3.5 1.8 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.6 KEG14489.1 - 0.033 14.1 1.6 0.2 11.6 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14489.1 - 0.11 12.9 0.6 1.1e+02 3.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEG14489.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG14489.1 - 0.23 11.6 1.9 0.25 11.4 0.3 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KEG14489.1 - 0.42 10.7 7.9 2.2 8.4 1.6 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3623 PF12291.8 KEG14490.1 - 0.0062 15.8 3.9 0.023 13.9 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3623) DUF2207 PF09972.9 KEG14490.1 - 3.3 6.4 5.1 4.5 5.9 0.0 2.4 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 KEG14492.1 - 2.9e-63 213.7 0.0 3.3e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14492.1 - 1.7e-39 135.7 0.0 2.1e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14492.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEG14492.1 - 0.00062 18.8 0.1 0.00097 18.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEG14492.1 - 0.0037 16.6 0.1 0.0075 15.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG14492.1 - 0.0047 15.8 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEG14492.1 - 0.019 14.9 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEG14492.1 - 0.057 12.5 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 KEG14492.1 - 0.084 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KEG14492.1 - 0.11 12.1 0.0 0.78 9.3 0.0 2.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_6 PF01341.17 KEG14492.1 - 0.21 11.2 0.0 0.32 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 AAA_23 PF13476.6 KEG14493.1 - 7e-29 101.8 0.0 7e-29 101.8 0.0 6.6 1 1 2 3 3 2 1 AAA domain SMC_N PF02463.19 KEG14493.1 - 4.7e-15 55.6 0.0 1.6e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEG14493.1 - 7e-09 35.9 0.1 0.00086 19.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KEG14493.1 - 7.3e-08 32.5 0.1 3.9e-07 30.2 0.1 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KEG14493.1 - 2e-05 24.5 21.7 0.0057 16.4 4.1 5.1 3 2 0 4 4 4 2 AAA ATPase domain Rad50_zn_hook PF04423.14 KEG14493.1 - 0.00012 21.9 4.0 0.00061 19.6 0.0 4.2 3 0 0 3 3 3 1 Rad50 zinc hook motif AAA_29 PF13555.6 KEG14493.1 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEG14493.1 - 0.0016 19.0 0.0 0.0016 19.0 0.0 6.0 5 2 1 6 6 6 2 ABC transporter RsgA_GTPase PF03193.16 KEG14493.1 - 0.0065 16.4 0.7 0.31 10.9 0.0 3.3 2 0 0 2 2 2 1 RsgA GTPase DUF4200 PF13863.6 KEG14493.1 - 0.012 16.0 8.0 0.012 16.0 8.0 10.9 7 4 3 10 10 9 0 Domain of unknown function (DUF4200) Baculo_IE-1 PF05290.11 KEG14493.1 - 0.052 13.5 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) NPV_P10 PF05531.12 KEG14493.1 - 0.058 13.9 39.7 1.8 9.1 1.9 9.6 7 3 3 10 10 10 0 Nucleopolyhedrovirus P10 protein zf-met PF12874.7 KEG14493.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEG14493.1 - 0.12 12.7 0.1 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding WPP PF13943.6 KEG14493.1 - 0.13 12.7 1.7 0.68 10.4 1.7 2.3 1 0 0 1 1 1 0 WPP domain SLATT_1 PF18181.1 KEG14493.1 - 0.25 11.3 6.5 0.34 10.8 1.5 3.6 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 MMR_HSR1 PF01926.23 KEG14493.1 - 0.52 10.4 5.5 3.5 7.7 0.1 3.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG14493.1 - 0.79 10.1 0.0 0.79 10.1 0.0 6.6 3 2 0 3 3 2 0 AAA ATPase domain Filo_VP35 PF02097.15 KEG14493.1 - 6.1 5.8 7.8 0.38 9.8 0.6 2.6 3 0 0 3 3 3 0 Filoviridae VP35 Ribosomal_S26e PF01283.19 KEG14494.1 - 3.4e-35 120.7 2.4 4e-35 120.5 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Hormone_2 PF00123.20 KEG14494.1 - 0.095 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Peptide hormone Rad51 PF08423.11 KEG14495.1 - 3.3e-128 426.3 0.3 3.8e-128 426.1 0.3 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KEG14495.1 - 2.9e-10 40.1 0.2 4.5e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KEG14495.1 - 3.3e-10 39.9 0.1 4.8e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KEG14495.1 - 0.00012 21.6 1.0 0.0004 19.8 1.0 1.8 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KEG14495.1 - 0.0016 19.0 0.0 0.0052 17.4 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KEG14495.1 - 0.0042 16.5 0.1 0.019 14.3 0.0 1.9 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KEG14495.1 - 0.048 13.9 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KEG14495.1 - 0.13 11.4 0.1 0.56 9.3 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein AAA_24 PF13479.6 KEG14495.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 KEG14498.1 - 1.8e-44 151.5 0.1 2.1e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEG14498.1 - 8.1e-11 41.4 0.0 8.1e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5425 PF17472.2 KEG14498.1 - 0.038 14.8 0.0 0.087 13.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5425) zf_CCCH_4 PF18345.1 KEG14499.1 - 0.0034 17.4 0.1 0.0067 16.4 0.1 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KEG14499.1 - 0.0039 17.9 0.0 0.0072 17.0 0.0 1.4 1 0 0 1 1 1 1 Torus domain Inhibitor_I36 PF03995.13 KEG14499.1 - 0.11 12.5 0.0 1.9 8.5 0.0 2.5 3 0 0 3 3 3 0 Peptidase inhibitor family I36 Topoisom_bac PF01131.20 KEG14501.1 - 5.5e-21 75.0 0.0 9.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 DNA topoisomerase CAP_N PF01213.19 KEG14501.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Topoisom_bac PF01131.20 KEG14502.1 - 5.6e-51 173.8 0.1 3.1e-50 171.4 0.1 1.9 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KEG14502.1 - 3.7e-17 62.4 0.0 1.2e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 KEG14502.1 - 0.00017 22.0 0.0 0.0028 18.1 0.0 2.5 2 0 0 2 2 2 1 Toprim domain Peptidase_C2 PF00648.21 KEG14503.1 - 7.1e-38 130.3 0.0 1.2e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KEG14503.1 - 2.4e-26 92.7 0.0 1.5e-05 25.3 0.0 7.5 7 0 0 7 7 7 5 Calpain large subunit, domain III LRR_1 PF00560.33 KEG14503.1 - 1.7 9.5 4.0 1.3e+02 3.8 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Sugar_tr PF00083.24 KEG14507.1 - 0.44 9.4 13.0 0.56 9.0 13.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 KEG14508.1 - 2.1e-14 53.2 28.6 1.4e-13 50.5 28.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG14508.1 - 9.2e-05 21.5 4.5 9.2e-05 21.5 4.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.32 KEG14510.1 - 1.4e-17 63.7 10.3 1.2e-06 29.1 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG14510.1 - 3.4e-09 36.9 0.1 0.00018 21.7 0.1 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEG14510.1 - 3.5e-05 22.6 0.5 0.0057 15.4 0.2 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEG14510.1 - 0.034 13.1 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KEG14510.1 - 0.098 13.2 2.2 2 9.0 0.2 3.2 3 0 0 3 3 3 0 PQQ-like domain BNR PF02012.20 KEG14511.1 - 8.7e-05 22.0 0.2 3.3 8.1 0.0 4.6 4 0 0 4 4 4 2 BNR/Asp-box repeat BNR_6 PF15899.5 KEG14511.1 - 0.072 13.2 0.0 1.7 8.9 0.0 2.8 2 0 0 2 2 2 0 BNR-Asp box repeat PSII_BNR PF14870.6 KEG14511.1 - 0.1 11.8 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 SNARE PF05739.19 KEG14512.1 - 0.00091 19.2 1.3 0.0037 17.2 1.3 2.1 1 0 0 1 1 1 1 SNARE domain PspA_IM30 PF04012.12 KEG14512.1 - 0.013 15.1 3.0 0.013 15.1 3.0 3.0 2 1 1 3 3 3 0 PspA/IM30 family V-SNARE_C PF12352.8 KEG14512.1 - 0.027 14.8 1.6 2.5 8.4 1.4 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DASH_Duo1 PF08651.10 KEG14512.1 - 0.046 13.5 2.7 1.2 9.0 0.1 3.3 3 1 0 3 3 3 0 DASH complex subunit Duo1 TrmB PF01978.19 KEG14512.1 - 0.05 13.5 1.6 0.29 11.0 0.1 2.7 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DUF745 PF05335.13 KEG14512.1 - 0.065 13.0 6.8 0.21 11.3 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sec2p PF06428.11 KEG14512.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.1 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 KEG14512.1 - 0.2 11.7 11.2 3.9 7.5 1.9 3.3 1 1 3 4 4 4 0 Laminin Domain II DUF2203 PF09969.9 KEG14512.1 - 0.28 11.9 7.9 0.21 12.3 2.5 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) KxDL PF10241.9 KEG14512.1 - 0.82 10.0 5.3 1.9 8.8 1.5 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein TBCA PF02970.16 KEG14512.1 - 1.9 8.9 12.4 0.43 10.9 4.5 3.2 2 1 2 4 4 4 0 Tubulin binding cofactor A DMPK_coil PF08826.10 KEG14512.1 - 2.3 8.4 10.8 0.72 10.0 0.2 3.1 3 1 0 3 3 3 0 DMPK coiled coil domain like AAT PF03417.16 KEG14513.1 - 0.00084 19.1 0.7 0.062 13.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Lant_dehydr_C PF14028.6 KEG14513.1 - 0.0082 15.7 2.4 0.071 12.6 0.4 2.1 1 1 1 2 2 2 1 Lantibiotic biosynthesis dehydratase C-term WXG100 PF06013.12 KEG14513.1 - 0.011 15.9 0.5 0.061 13.6 0.3 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CdvA PF18822.1 KEG14513.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.9 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DHR10 PF18595.1 KEG14513.1 - 0.075 13.1 11.3 0.67 10.0 3.8 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain IZUMO PF15005.6 KEG14513.1 - 0.93 10.0 4.8 0.97 9.9 0.3 2.6 1 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated TQ PF18202.1 KEG14513.1 - 1 9.9 8.2 0.93 10.0 6.6 1.6 1 1 0 1 1 1 0 T-Q ester bond containing domain CotJB PF12652.7 KEG14513.1 - 6.9 7.0 7.8 13 6.1 1.7 3.1 2 1 1 3 3 3 0 CotJB protein DUF148 PF02520.17 KEG14513.1 - 7.4 6.7 11.8 0.25 11.5 0.8 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF148 OmpH PF03938.14 KEG14513.1 - 8 6.8 14.1 9.8 6.5 0.6 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) WXG100 PF06013.12 KEG14514.1 - 0.012 15.8 0.4 0.21 11.8 0.0 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG VirD1 PF07328.11 KEG14514.1 - 0.13 12.2 0.1 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 T-DNA border endonuclease VirD1 zf-rbx1 PF12678.7 KEG14516.1 - 8e-25 86.9 12.7 1.1e-24 86.5 12.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEG14516.1 - 2.2e-17 62.9 9.7 2.7e-17 62.6 9.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KEG14516.1 - 5e-06 26.8 14.8 0.00014 22.1 14.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG14516.1 - 9.7e-06 25.3 2.6 9.7e-06 25.3 2.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG14516.1 - 0.00048 19.9 11.7 0.003 17.4 11.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KEG14516.1 - 0.0057 16.3 13.9 0.026 14.1 2.5 2.3 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KEG14516.1 - 0.02 14.6 2.4 0.02 14.6 2.4 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KEG14516.1 - 0.026 14.4 9.8 0.086 12.7 4.1 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG14516.1 - 0.037 14.1 6.9 0.09 12.8 6.9 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 KEG14516.1 - 0.066 13.4 10.2 0.11 12.7 10.2 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 KEG14516.1 - 0.071 13.3 8.6 0.2 11.8 8.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 KEG14516.1 - 2 8.4 13.6 22 5.1 13.6 2.5 1 1 0 1 1 1 0 zinc-RING finger domain Methyltransf_12 PF08242.12 KEG14517.1 - 9.8e-10 39.1 0.0 2.5e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEG14517.1 - 1e-09 38.5 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG14517.1 - 9.6e-07 29.4 0.1 4e-05 24.2 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG14517.1 - 3.1e-06 27.1 0.1 2.5e-05 24.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG14517.1 - 0.00052 20.6 0.2 0.013 16.1 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KEG14517.1 - 0.01 15.5 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Helicase_C PF00271.31 KEG14518.1 - 2.5e-21 76.1 0.0 2.4e-19 69.7 0.0 2.3 1 1 0 2 2 2 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEG14518.1 - 4e-12 46.2 1.2 1.6e-11 44.2 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) P-II PF00543.22 KEG14518.1 - 0.14 12.8 0.0 19 6.0 0.0 2.6 2 0 0 2 2 2 0 Nitrogen regulatory protein P-II Acetyltransf_10 PF13673.7 KEG14519.1 - 9.1e-10 38.6 0.1 1.2e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG14519.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KEG14519.1 - 6.2e-09 36.1 0.0 8.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEG14519.1 - 4.1e-07 30.3 0.2 7.4e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RHSP PF07999.11 KEG14520.1 - 8.8e-93 311.5 0.0 1.5e-92 310.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon hot spot protein Ank PF00023.30 KEG14521.1 - 0.003 18.0 0.0 2.1 9.0 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KEG14521.1 - 0.16 12.3 0.6 27 5.2 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) RRM_1 PF00076.22 KEG14522.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.21 KEG14524.1 - 2.1e-64 217.2 0.0 2.8e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KEG14524.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEG14524.1 - 0.048 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KEG14524.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3439 PF11921.8 KEG14525.1 - 9 6.3 11.3 4 7.4 6.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) C2 PF00168.30 KEG14526.1 - 0.00057 20.1 0.0 0.0034 17.6 0.0 2.2 2 0 0 2 2 2 1 C2 domain CC2D2AN-C2 PF15625.6 KEG14526.1 - 0.0086 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF4336 PF14234.6 KEG14527.1 - 0.03 13.5 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) Pkinase PF00069.25 KEG14528.1 - 3.4e-21 75.8 0.0 6.8e-09 35.5 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14528.1 - 0.0002 20.7 0.0 0.19 11.0 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase DDRGK PF09756.9 KEG14528.1 - 0.025 14.2 4.2 0.61 9.6 0.0 2.5 2 0 0 2 2 2 0 DDRGK domain MPP6 PF10175.9 KEG14528.1 - 0.75 10.3 5.4 14 6.2 2.7 2.6 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Cwf_Cwc_15 PF04889.12 KEG14528.1 - 7 6.3 14.7 0.42 10.3 5.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Hexapep PF00132.24 KEG14529.1 - 0.0032 17.1 7.2 0.75 9.6 0.1 4.1 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) DEAD PF00270.29 KEG14530.1 - 6.6e-40 136.7 0.1 1.5e-39 135.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14530.1 - 1e-27 96.6 0.4 3.8e-26 91.6 0.2 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KEG14530.1 - 0.0025 17.2 0.1 0.0071 15.7 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit B2 PF11473.8 KEG14530.1 - 0.0047 16.7 0.6 1.7 8.5 0.1 2.5 1 1 1 2 2 2 2 RNA binding protein B2 DUF1460 PF07313.12 KEG14530.1 - 0.0055 16.1 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1460) AAA_22 PF13401.6 KEG14530.1 - 0.056 13.7 2.1 0.31 11.3 0.7 2.8 2 2 0 2 2 2 0 AAA domain HYLS1_C PF15311.6 KEG14531.1 - 0.0037 18.0 0.4 0.0082 16.9 0.4 1.5 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus BK_channel_a PF03493.18 KEG14532.1 - 6.5e-14 51.9 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit RVT_1 PF00078.27 KEG14533.1 - 8e-47 159.6 0.0 1.5e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KEG14533.1 - 4.2e-08 33.5 0.0 1.2e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 RNase H zf-C2H2_4 PF13894.6 KEG14533.1 - 9.6e-07 29.1 39.1 0.32 11.9 0.4 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 KEG14533.1 - 1.3e-06 28.5 14.6 0.004 17.4 0.3 5.6 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Exo_endo_phos_2 PF14529.6 KEG14533.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-C2H2 PF00096.26 KEG14533.1 - 0.038 14.5 29.7 0.27 11.8 0.2 6.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KEG14533.1 - 0.15 11.8 0.1 0.15 11.8 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KEG14533.1 - 0.68 9.6 10.4 14 5.4 0.4 5.0 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KEG14533.1 - 0.96 9.8 14.7 32 4.9 0.2 5.5 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KEG14533.1 - 1 9.4 10.1 4.4 7.4 0.0 4.2 5 0 0 5 5 5 0 BED zinc finger Dscam_C PF12355.8 KEG14533.1 - 1.2 10.1 4.1 0.9 10.5 1.6 2.1 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CagA PF03507.13 KEG14536.1 - 0.0079 16.2 0.1 0.087 12.8 0.0 2.0 2 0 0 2 2 2 1 CagA exotoxin PspB PF06667.12 KEG14536.1 - 0.019 15.0 7.5 0.13 12.3 3.0 2.5 2 1 0 2 2 2 0 Phage shock protein B Peptidase_C101 PF16218.5 KEG14536.1 - 0.052 12.8 2.1 0.081 12.2 1.9 1.3 1 1 0 1 1 1 0 Peptidase family C101 CHAD PF05235.14 KEG14536.1 - 0.052 13.5 15.3 0.061 13.3 15.3 1.1 1 0 0 1 1 1 0 CHAD domain TraI_2B PF18340.1 KEG14536.1 - 0.14 12.2 0.9 0.31 11.1 0.3 1.9 1 1 1 2 2 2 0 DNA relaxase TraI 2B/2B-like domain PKcGMP_CC PF16808.5 KEG14536.1 - 0.18 11.7 8.8 0.21 11.5 1.5 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF948 PF06103.11 KEG14536.1 - 0.24 11.7 0.9 4.6 7.6 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KEG14536.1 - 0.31 11.2 5.1 3 8.0 4.4 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 KEG14536.1 - 0.9 9.8 9.3 0.4 10.9 4.6 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Ntox1 PF15500.6 KEG14536.1 - 1.8 8.9 8.0 6.5 7.2 1.7 2.2 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 DEAD PF00270.29 KEG14537.1 - 2.1e-41 141.6 0.0 7.9e-41 139.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14537.1 - 5.8e-32 110.3 0.0 1.1e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KEG14537.1 - 0.0019 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KEG14537.1 - 0.063 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase FUSC PF04632.12 KEG14538.1 - 3.8 5.9 10.4 0.44 9.0 5.3 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family TPR_1 PF00515.28 KEG14539.1 - 0.2 11.5 2.8 7.8 6.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14539.1 - 0.51 10.6 4.5 5 7.5 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Syntaxin PF00804.25 KEG14540.1 - 4.2e-24 85.3 14.2 4.2e-24 85.3 14.2 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KEG14540.1 - 6e-14 51.8 0.9 6e-14 51.8 0.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KEG14540.1 - 5.6e-06 26.7 9.0 0.00095 19.5 2.5 3.1 3 1 1 4 4 4 2 Syntaxin-like protein SecE PF00584.20 KEG14540.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex PXA PF02194.15 KEG14540.1 - 0.094 12.7 4.9 0.13 12.2 4.4 1.5 1 1 0 1 1 1 0 PXA domain CCP_MauG PF03150.14 KEG14540.1 - 0.14 12.8 2.6 0.14 12.8 1.2 1.7 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Laminin_II PF06009.12 KEG14540.1 - 0.43 10.6 9.0 0.95 9.5 0.7 2.9 2 2 1 3 3 3 0 Laminin Domain II DASH_Duo1 PF08651.10 KEG14540.1 - 1 9.2 6.0 5.6 6.8 0.4 3.4 4 1 0 4 4 4 0 DASH complex subunit Duo1 CREPT PF16566.5 KEG14540.1 - 2.7 8.2 12.9 0.11 12.6 4.4 2.4 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FUSC PF04632.12 KEG14540.1 - 5.1 5.5 7.1 1.6 7.2 2.7 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KEG14540.1 - 5.5 7.0 10.3 6.8 6.8 0.2 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 KEG14540.1 - 5.5 7.7 12.6 2.8 8.7 0.4 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) MgtE PF01769.16 KEG14541.1 - 0.05 14.0 2.8 0.086 13.2 2.8 1.3 1 0 0 1 1 1 0 Divalent cation transporter Coa1 PF08695.10 KEG14541.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 CoA_binding_3 PF13727.6 KEG14541.1 - 0.11 12.4 1.3 0.19 11.7 1.3 1.3 1 0 0 1 1 1 0 CoA-binding domain DUF2520 PF10728.9 KEG14543.1 - 0.061 13.1 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DUF1289 PF06945.13 KEG14548.1 - 2.1 8.2 5.1 22 4.9 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1289) ATP-grasp_4 PF13535.6 KEG14550.1 - 8.2e-13 48.3 0.0 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KEG14550.1 - 6.6e-07 29.5 0.0 2.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KEG14550.1 - 0.021 14.6 0.5 0.48 10.2 0.1 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 KEG14550.1 - 0.036 13.5 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 KEG14550.1 - 0.037 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Integrase_Zn PF02022.19 KEG14550.1 - 1.7 8.7 3.9 0.4 10.7 0.2 1.9 2 0 0 2 2 2 0 Integrase Zinc binding domain SKI PF01202.22 KEG14551.1 - 3.1e-07 30.7 0.0 3.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KEG14551.1 - 1.2e-05 25.4 0.0 1.9e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG14551.1 - 0.00033 21.1 0.0 0.00051 20.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KEG14551.1 - 0.00084 19.1 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 KEG14551.1 - 0.0013 19.3 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG14551.1 - 0.0017 18.6 0.1 0.0035 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEG14551.1 - 0.0019 18.4 0.0 0.0036 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEG14551.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KEG14551.1 - 0.043 13.6 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEG14551.1 - 0.05 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KEG14551.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEG14551.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEG14551.1 - 0.07 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.6 KEG14551.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_25 PF13481.6 KEG14551.1 - 0.14 11.7 0.6 0.28 10.7 0.4 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEG14551.1 - 0.17 12.3 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.32 KEG14552.1 - 8.4e-34 115.0 28.6 0.00013 22.7 0.0 11.4 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG14552.1 - 2.9e-11 43.5 4.0 0.13 12.6 0.0 7.1 3 3 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KEG14552.1 - 0.0034 16.2 0.0 0.031 13.0 0.0 2.6 3 0 0 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 KEG14552.1 - 0.0099 15.2 0.9 7.3 5.8 0.0 3.9 3 2 2 5 5 5 2 WD40-like domain PD40 PF07676.12 KEG14552.1 - 0.071 13.1 0.1 11 6.1 0.0 4.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat SecA_PP_bind PF01043.20 KEG14552.1 - 0.077 13.7 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 SecA preprotein cross-linking domain WD40_3 PF15911.5 KEG14552.1 - 0.2 11.7 3.6 3 7.9 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Amastin PF07344.11 KEG14553.1 - 0.12 12.2 11.3 0.085 12.7 9.0 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein AA_permease PF00324.21 KEG14554.1 - 3.6e-47 161.1 38.2 5e-47 160.6 38.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEG14554.1 - 7.1e-15 54.8 47.5 1.2e-14 54.0 47.5 1.3 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KEG14554.1 - 9.6e-09 34.8 1.6 1.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Solute carrier family 12 ETF PF01012.21 KEG14555.1 - 3.8e-34 118.2 9.5 5.9e-34 117.5 9.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KEG14555.1 - 1.9e-32 111.1 3.2 3e-32 110.5 0.1 2.4 2 1 1 3 3 3 1 Electron transfer flavoprotein FAD-binding domain AMP-binding PF00501.28 KEG14556.1 - 9.9e-59 199.0 0.1 3.6e-57 193.9 0.2 2.7 2 1 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEG14556.1 - 7e-11 43.0 0.0 2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGEF_N PF00618.20 KEG14558.1 - 1.2e-12 48.0 0.1 3.1e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 KEG14558.1 - 8.3e-05 22.9 0.2 0.00035 20.8 0.0 2.1 1 1 1 2 2 2 1 RasGEF domain Surp PF01805.20 KEG14560.1 - 0.0093 15.9 0.6 0.038 14.0 0.1 2.2 2 0 0 2 2 2 1 Surp module COX6B PF02297.17 KEG14562.1 - 2.4e-14 53.3 2.2 2.6e-14 53.2 2.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KEG14562.1 - 0.00044 20.2 1.4 0.00072 19.5 1.4 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Rab5ip PF07019.12 KEG14563.1 - 1.2e-19 70.6 5.7 1.5e-19 70.4 5.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) KR PF08659.10 KEG14564.1 - 0.14 12.1 0.5 0.33 10.9 0.5 1.7 1 0 0 1 1 1 0 KR domain PSD2 PF07624.11 KEG14564.1 - 0.18 11.6 0.9 0.63 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) MRPL52 PF18699.1 KEG14564.1 - 1.5 9.1 7.7 0.58 10.4 0.3 3.0 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Tup_N PF08581.10 KEG14564.1 - 1.6 9.0 26.9 0.23 11.8 0.5 5.8 5 1 1 6 6 6 0 Tup N-terminal LRR_4 PF12799.7 KEG14565.1 - 1.3e-19 69.9 12.5 2.5e-08 34.1 2.5 3.8 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) AMPK1_CBM PF16561.5 KEG14565.1 - 2e-12 47.1 0.0 4.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase LRR_8 PF13855.6 KEG14565.1 - 2.5e-11 43.1 14.0 4e-06 26.5 3.7 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KEG14565.1 - 4.7e-10 39.2 0.1 0.00095 18.7 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat SCAB-Ig PF16709.5 KEG14565.1 - 1.9e-06 27.8 1.6 0.069 13.2 0.0 3.8 5 0 0 5 5 5 2 Ig domain of plant-specific actin-binding protein LRR_6 PF13516.6 KEG14565.1 - 0.0042 17.0 13.2 9.6 6.5 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich repeat CBM_48 PF02922.18 KEG14565.1 - 0.033 14.5 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) TMEM190 PF15431.6 KEG14565.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 LRR_1 PF00560.33 KEG14565.1 - 0.094 13.3 12.4 55 4.9 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat MMR_HSR1 PF01926.23 KEG14566.1 - 2.5e-16 59.7 0.0 4.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG14566.1 - 4.9e-08 33.0 0.0 5.4e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KEG14566.1 - 1.7e-06 27.7 0.0 0.0018 17.8 0.0 2.6 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KEG14566.1 - 0.0099 15.4 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DnaJ PF00226.31 KEG14567.1 - 2.2e-22 78.9 0.1 4.9e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 KEG14568.1 - 3.4e-33 115.9 0.0 4.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Roc PF08477.13 KEG14569.1 - 4.8e-13 49.4 0.0 9.5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEG14569.1 - 7.1e-11 42.0 0.1 1.3e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEG14569.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-MIZ PF02891.20 KEG14571.1 - 2e-09 37.1 6.2 2e-09 37.1 6.2 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KEG14571.1 - 0.00076 19.2 2.0 0.0017 18.1 2.0 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Methyltransf_34 PF11312.8 KEG14571.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase zf-TFIIB PF13453.6 KEG14571.1 - 0.81 9.1 9.1 0.41 10.0 4.6 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Auto_anti-p27 PF06677.12 KEG14571.1 - 4.5 7.5 10.2 0.16 12.2 2.6 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ABC_tran PF00005.27 KEG14572.1 - 1.4e-35 122.8 0.1 7.2e-35 120.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KEG14572.1 - 1.9e-28 99.9 6.3 2.5e-28 99.5 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KEG14572.1 - 3e-06 26.8 0.6 0.00075 19.0 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEG14572.1 - 0.00098 19.5 0.1 0.0032 17.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEG14572.1 - 0.0016 18.2 1.1 0.0097 15.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KEG14572.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEG14572.1 - 0.0067 16.7 0.0 0.092 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KEG14572.1 - 0.024 13.8 0.0 0.072 12.2 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KEG14572.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KEG14572.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KEG14572.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KEG14572.1 - 0.14 12.7 0.2 0.14 12.7 0.2 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KEG14572.1 - 0.16 12.1 0.1 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase NAP PF00956.18 KEG14572.1 - 2.1 7.4 7.2 3.7 6.6 1.7 2.2 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Coilin_N PF15862.5 KEG14572.1 - 6.3 6.6 10.1 12 5.7 0.1 2.4 2 0 0 2 2 2 0 Coilin N-terminus Siah-Interact_N PF09032.11 KEG14574.1 - 0.0014 18.9 2.2 0.35 11.2 0.7 2.6 2 0 0 2 2 2 2 Siah interacting protein, N terminal LPP PF04728.13 KEG14574.1 - 0.011 16.1 1.8 0.46 10.9 0.6 3.4 2 2 0 2 2 2 0 Lipoprotein leucine-zipper DUF5082 PF16888.5 KEG14574.1 - 0.093 13.0 7.3 0.2 11.9 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Csm4_C PF17953.1 KEG14574.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain TMCO5 PF14992.6 KEG14574.1 - 1.5 8.3 9.6 2.1 7.8 0.9 2.4 2 1 0 2 2 2 0 TMCO5 family Seryl_tRNA_N PF02403.22 KEG14574.1 - 2.6 8.3 10.2 2.7 8.3 0.2 3.6 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KEG14574.1 - 2.9 8.4 5.1 35 4.9 0.2 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 KEG14574.1 - 3.9 5.3 7.1 7 4.4 7.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 KEG14574.1 - 4.1 7.5 10.1 4 7.5 1.2 2.7 3 0 0 3 3 3 0 FlxA-like protein DUF16 PF01519.16 KEG14574.1 - 6.8 7.2 8.1 1 9.9 1.0 2.7 3 1 0 3 3 3 0 Protein of unknown function DUF16 FSH1 PF03959.13 KEG14575.1 - 8.1e-23 81.2 0.1 1.3e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.10 KEG14575.1 - 1.3e-21 77.3 0.0 4.9e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KEG14575.1 - 2.9e-14 53.1 0.0 9.3e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG14575.1 - 0.00026 20.6 0.1 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RWD PF05773.22 KEG14575.1 - 0.00037 20.8 0.0 0.0012 19.1 0.0 1.9 1 1 1 2 2 2 1 RWD domain AA_kinase PF00696.28 KEG14576.1 - 2.6e-36 125.5 0.0 4.3e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 KEG14576.1 - 9.8e-14 50.7 7.0 2.3e-11 42.9 4.4 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family SNN_transmemb PF09049.10 KEG14577.1 - 4.3 7.4 13.6 84 3.2 0.3 5.3 4 0 0 4 4 4 0 Stannin transmembrane Chal_sti_synt_N PF00195.19 KEG14580.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Gon7 PF08738.10 KEG14580.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Gon7 family DUF3489 PF11994.8 KEG14581.1 - 0.18 11.9 0.0 4.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3489) Pkinase_Tyr PF07714.17 KEG14582.1 - 1.2e-11 44.5 0.2 1.2e-10 41.1 0.2 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEG14582.1 - 6.8e-10 38.7 0.1 5.6e-08 32.5 0.1 2.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KEG14582.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-C6H2 PF15801.5 KEG14584.1 - 2.5e-10 40.5 6.1 4.4e-10 39.7 6.1 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KEG14584.1 - 0.0051 16.9 3.1 0.0092 16.1 3.1 1.4 1 0 0 1 1 1 1 MYND finger CDP-OH_P_transf PF01066.21 KEG14586.1 - 6e-13 49.4 0.3 6e-13 49.4 0.3 3.2 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase ABC2_membrane_3 PF12698.7 KEG14588.1 - 0.00024 20.3 0.5 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein YwiC PF14256.6 KEG14588.1 - 2.8 8.3 9.0 7 7.0 0.2 3.0 2 1 1 3 3 3 0 YwiC-like protein 6PF2K PF01591.18 KEG14589.1 - 2.8e-62 210.0 0.0 4.7e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.7 KEG14589.1 - 2e-13 50.7 0.1 6.3e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG14589.1 - 1.4e-12 47.6 1.0 5.7e-11 42.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEG14589.1 - 1.8e-10 41.2 0.6 4e-08 33.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEG14589.1 - 2.9e-10 40.1 0.2 1.1e-06 28.8 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.6 KEG14589.1 - 1e-08 35.4 0.4 2.3e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.6 KEG14589.1 - 3.1e-08 33.2 0.0 0.0012 19.2 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat His_Phos_1 PF00300.22 KEG14589.1 - 0.0082 15.9 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KEG14589.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 KEG14589.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.14 KEG14589.1 - 0.023 14.7 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF5402 PF17393.2 KEG14589.1 - 0.2 11.6 0.6 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5402) RNA_pol_Rpb4 PF03874.16 KEG14590.1 - 0.12 12.7 0.0 0.64 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb4 Pkinase PF00069.25 KEG14591.1 - 1.6e-55 188.3 0.0 5.7e-35 121.0 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14591.1 - 3.2e-30 105.3 0.0 4.7e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG14591.1 - 0.0008 18.3 0.0 0.0018 17.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG14591.1 - 0.0044 16.4 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEG14591.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ubiquitin_2 PF14560.6 KEG14592.1 - 2e-11 44.2 0.0 3.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_4 PF12799.7 KEG14592.1 - 9.5e-08 32.2 6.9 0.23 11.9 0.1 4.7 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG14592.1 - 8.5e-06 25.4 0.1 0.87 9.1 0.0 3.7 2 2 0 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 KEG14592.1 - 9.1e-05 22.1 4.6 0.82 9.5 0.3 4.3 3 1 0 3 3 3 2 Leucine rich repeat ubiquitin PF00240.23 KEG14592.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family LRR_6 PF13516.6 KEG14592.1 - 0.54 10.5 1.9 66 3.9 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Acyl-CoA_dh_2 PF08028.11 KEG14594.1 - 0.022 15.1 2.4 0.027 14.7 2.4 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_14 PF13428.6 KEG14595.1 - 9.3e-11 41.6 37.5 0.0009 19.9 0.1 10.7 4 3 4 10 10 10 4 Tetratricopeptide repeat HAT PF02184.16 KEG14595.1 - 2.4e-06 27.4 15.5 1.9 8.5 0.2 7.2 7 0 0 7 7 7 2 HAT (Half-A-TPR) repeat TPR_9 PF13371.6 KEG14595.1 - 2.8e-05 24.2 7.2 0.017 15.2 0.1 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEG14595.1 - 0.0011 19.5 12.9 33 5.4 0.1 7.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14595.1 - 0.0024 18.1 0.5 13 6.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2063 PF09836.9 KEG14595.1 - 0.0086 16.3 0.0 0.046 13.9 0.0 2.3 1 0 0 1 1 1 1 Putative DNA-binding domain SecA_SW PF07516.13 KEG14595.1 - 0.024 14.7 1.4 0.059 13.4 1.4 1.7 1 0 0 1 1 1 0 SecA Wing and Scaffold domain TPR_19 PF14559.6 KEG14595.1 - 0.034 14.7 8.8 4.9 7.7 0.1 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14595.1 - 0.044 14.4 32.0 0.61 10.8 0.4 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Suf PF05843.14 KEG14595.1 - 0.063 13.3 2.5 5.1 7.0 0.0 3.7 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) CCP_MauG PF03150.14 KEG14595.1 - 0.066 13.9 2.2 0.51 11.0 0.1 2.9 3 0 0 3 3 3 0 Di-haem cytochrome c peroxidase TPR_2 PF07719.17 KEG14595.1 - 0.099 12.8 6.4 4.1 7.8 1.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Arf PF00025.21 KEG14596.1 - 5.7e-16 58.5 0.0 2e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family PH PF00169.29 KEG14596.1 - 4.2e-08 33.6 0.0 1.1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 PH domain SRPRB PF09439.10 KEG14596.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Bep_C_terminal PF17841.1 KEG14596.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) CHAP PF05257.16 KEG14597.1 - 2.2e-11 44.2 0.0 4.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 CHAP domain SET PF00856.28 KEG14598.1 - 2.4e-10 41.1 0.0 5.6e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 SET domain C2 PF00168.30 KEG14599.1 - 1.5e-60 201.9 0.4 9.5e-14 51.5 0.0 8.9 9 0 0 9 9 9 7 C2 domain C2 PF00168.30 KEG14600.1 - 2.4e-27 95.2 0.3 1.4e-09 38.1 0.0 4.6 4 0 0 4 4 4 4 C2 domain NT-C2 PF10358.9 KEG14600.1 - 0.016 14.9 0.1 0.17 11.6 0.0 2.7 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins AAA PF00004.29 KEG14603.1 - 1.5e-43 148.4 0.0 3.3e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG14603.1 - 3.4e-16 58.8 0.3 1e-15 57.2 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 KEG14603.1 - 7e-07 29.3 0.2 3.4e-06 27.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG14603.1 - 1.1e-06 29.2 0.6 8.9e-05 22.9 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 KEG14603.1 - 2.1e-06 27.9 0.0 5.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KEG14603.1 - 8.7e-06 25.6 1.0 1.9e-05 24.5 1.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 KEG14603.1 - 2.8e-05 23.9 0.0 6.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG14603.1 - 0.00013 22.3 2.3 0.012 15.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KEG14603.1 - 0.00018 21.5 0.0 0.078 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KEG14603.1 - 0.00098 18.5 0.3 0.08 12.3 0.0 2.6 3 0 0 3 3 3 1 KaiC AAA_33 PF13671.6 KEG14603.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEG14603.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KEG14603.1 - 0.0027 18.3 0.3 0.016 15.7 0.0 2.5 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 KEG14603.1 - 0.0034 16.7 0.0 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KEG14603.1 - 0.0055 16.1 0.0 0.015 14.6 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KEG14603.1 - 0.0063 16.8 0.3 0.014 15.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 KEG14603.1 - 0.0069 16.3 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEG14603.1 - 0.012 15.9 0.3 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG14603.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KEG14603.1 - 0.014 15.1 0.1 0.064 12.9 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KEG14603.1 - 0.014 15.7 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KEG14603.1 - 0.018 14.2 0.3 0.073 12.2 0.0 2.1 4 0 0 4 4 4 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KEG14603.1 - 0.02 14.5 0.2 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 KEG14603.1 - 0.022 15.3 0.6 0.049 14.2 0.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_24 PF13479.6 KEG14603.1 - 0.03 14.0 0.0 0.096 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KEG14603.1 - 0.031 13.7 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein GHMP_kinases_C PF08544.13 KEG14603.1 - 0.041 14.2 0.0 20 5.6 0.0 3.2 3 0 0 3 3 3 0 GHMP kinases C terminal GrpE PF01025.19 KEG14603.1 - 0.042 13.5 0.4 0.1 12.3 0.2 1.8 2 0 0 2 2 1 0 GrpE AAA_7 PF12775.7 KEG14603.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KEG14603.1 - 0.049 12.7 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KEG14603.1 - 0.066 12.5 0.4 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DASH_Dad2 PF08654.10 KEG14603.1 - 0.079 13.4 0.6 0.29 11.6 0.6 2.0 1 0 0 1 1 1 0 DASH complex subunit Dad2 AAA_11 PF13086.6 KEG14603.1 - 0.085 12.6 1.5 0.37 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain DivIC PF04977.15 KEG14603.1 - 0.18 11.6 3.7 0.47 10.2 3.7 1.6 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.25 KEG14604.1 - 6.6e-68 229.4 0.0 1.8e-67 228.0 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) WWE PF02825.20 KEG14604.1 - 0.00026 21.5 1.0 0.00064 20.3 1.0 1.7 1 0 0 1 1 1 1 WWE domain AOX PF01786.17 KEG14605.1 - 3.4e-68 229.4 1.5 4.9e-68 228.9 1.5 1.2 1 0 0 1 1 1 1 Alternative oxidase CHASE9 PF17153.4 KEG14605.1 - 0.18 11.9 0.1 0.52 10.5 0.0 1.7 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular GCP_C_terminal PF04130.13 KEG14606.1 - 5.1e-39 134.6 0.1 1e-38 133.6 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEG14606.1 - 8.2e-32 111.0 0.0 1.4e-31 110.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF309 PF03745.14 KEG14606.1 - 0.069 12.9 0.4 0.29 10.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF309) 2HCT PF03390.15 KEG14606.1 - 0.079 11.6 0.1 0.26 9.9 0.0 1.7 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family Arf PF00025.21 KEG14607.1 - 5e-49 166.1 0.1 5.8e-49 165.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KEG14607.1 - 1.7e-13 50.5 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG14607.1 - 5.8e-13 49.1 0.0 8.5e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEG14607.1 - 2.2e-09 37.4 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG14607.1 - 4e-09 36.3 0.0 3.6e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KEG14607.1 - 1.7e-08 34.0 0.7 2.6e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KEG14607.1 - 5.4e-08 32.5 0.0 7.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KEG14607.1 - 7.6e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KEG14607.1 - 7.8e-07 28.7 1.1 1.5e-05 24.6 1.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KEG14607.1 - 0.00023 21.0 0.0 0.0033 17.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KEG14607.1 - 0.00028 20.8 0.4 0.075 12.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KEG14607.1 - 0.0091 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain cobW PF02492.19 KEG14607.1 - 0.013 15.1 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KEG14607.1 - 0.057 13.3 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 KEG14607.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 KEG14607.1 - 0.19 11.4 0.1 0.28 10.8 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF3520 PF12034.8 KEG14608.1 - 0.0099 16.0 0.8 0.031 14.4 0.7 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3520) Mei5 PF10376.9 KEG14608.1 - 0.089 12.6 1.0 0.2 11.5 1.0 1.6 1 1 0 1 1 1 0 Double-strand recombination repair protein BBP1_C PF15272.6 KEG14608.1 - 0.28 11.0 3.1 0.29 10.9 0.4 2.0 1 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DEAD PF00270.29 KEG14609.1 - 2.2e-33 115.5 0.1 4.5e-33 114.5 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14609.1 - 6e-31 107.1 0.1 2.9e-29 101.7 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG14609.1 - 0.00017 21.6 0.5 0.25 11.4 0.4 3.7 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEG14609.1 - 0.037 14.3 0.7 34 4.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain PRIMA1 PF16101.5 KEG14609.1 - 0.044 13.8 0.0 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FAM110_C PF14160.6 KEG14609.1 - 3.1 8.9 0.0 3.1 8.9 0.0 3.7 4 0 0 4 4 4 0 Centrosome-associated C terminus DUF4604 PF15377.6 KEG14611.1 - 0.23 11.9 15.0 0.28 11.6 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Ribosomal_L22e PF01776.17 KEG14612.1 - 1.4e-36 125.2 3.8 1.6e-36 125.0 3.8 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Pkinase PF00069.25 KEG14614.1 - 6.4e-49 166.7 0.0 3.2e-47 161.1 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14614.1 - 1.3e-24 86.9 0.1 4.5e-23 81.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG14614.1 - 0.00089 19.2 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KEG14614.1 - 0.075 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GDI PF00996.18 KEG14615.1 - 6.8e-179 594.9 0.3 7.7e-179 594.7 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor MalF_P2 PF14785.6 KEG14616.1 - 0.11 12.5 2.1 13 5.8 0.0 2.5 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain TMF_TATA_bd PF12325.8 KEG14616.1 - 0.26 11.5 19.2 0.17 12.1 13.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RE_HaeIII PF09556.10 KEG14616.1 - 0.37 9.8 2.6 0.62 9.1 2.6 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease Phlebovirus_NSM PF07246.11 KEG14616.1 - 0.57 9.5 7.7 0.93 8.8 7.7 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_13 PF13166.6 KEG14616.1 - 0.69 8.5 10.6 0.97 8.0 10.6 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 KEG14616.1 - 0.99 9.5 8.3 0.052 13.6 1.8 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 KEG14616.1 - 1.7 7.9 10.5 3 7.1 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KEG14616.1 - 2.4 8.8 17.7 1.5 9.5 9.5 3.0 1 1 1 2 2 2 0 SlyX Rootletin PF15035.6 KEG14616.1 - 3.2 7.7 23.8 14 5.6 10.5 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 KEG14616.1 - 4.8 7.7 22.9 0.28 11.6 4.6 3.1 2 1 1 3 3 3 0 Cell division protein ZapB GAS PF13851.6 KEG14616.1 - 5.4 6.3 20.7 7.6 5.8 18.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DTW PF03942.15 KEG14617.1 - 2e-26 93.0 0.0 3.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 DTW domain DUF4379 PF14311.6 KEG14618.1 - 2.8e-40 136.5 22.3 7e-17 61.5 3.3 3.3 3 0 0 3 3 3 3 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEG14618.1 - 0.00014 21.9 15.2 0.044 13.9 0.6 3.5 3 0 0 3 3 3 3 Zinc ribbon domain HypA PF01155.19 KEG14618.1 - 0.00075 19.5 16.8 0.24 11.4 0.6 3.2 1 1 2 3 3 3 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-MIZ PF02891.20 KEG14618.1 - 0.011 15.4 0.5 0.011 15.4 0.5 4.8 5 1 1 6 6 6 0 MIZ/SP-RING zinc finger OrfB_Zn_ribbon PF07282.11 KEG14618.1 - 2.9 7.9 17.2 4 7.5 0.6 4.6 3 2 1 4 4 4 0 Putative transposase DNA-binding domain zf-TRAF PF02176.18 KEG14619.1 - 0.0042 17.7 1.5 0.0042 17.7 1.5 3.1 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C2H2 PF00096.26 KEG14619.1 - 0.0046 17.3 7.8 0.053 14.0 0.0 4.6 4 0 0 4 4 4 1 Zinc finger, C2H2 type PyrI_C PF02748.15 KEG14619.1 - 0.11 12.5 1.8 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KEG14619.1 - 0.14 13.0 6.9 4.5 8.4 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 KEG14619.1 - 1.3 9.0 4.6 12 6.0 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HE PF16278.5 KEG14619.1 - 2 8.9 4.4 1.2 9.6 1.2 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Dynamin_M PF01031.20 KEG14621.1 - 1e-81 274.3 0.4 2.4e-81 273.1 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KEG14621.1 - 3.1e-50 170.5 0.1 9.7e-50 168.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KEG14621.1 - 2.7e-23 81.9 1.1 2.7e-23 81.9 1.1 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEG14621.1 - 1.2e-05 25.4 0.3 0.0002 21.4 0.3 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KEG14621.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KEG14621.1 - 0.097 13.0 0.3 0.96 9.8 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KEG14621.1 - 0.11 12.3 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain SpoU_methylas_C PF12105.8 KEG14621.1 - 0.18 11.5 0.3 1.4 8.7 0.0 2.5 3 0 0 3 3 3 0 SpoU, rRNA methylase, C-terminal SMC_N PF02463.19 KEG14621.1 - 0.21 11.0 0.1 0.6 9.5 0.1 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain LRR_9 PF14580.6 KEG14622.1 - 1.9e-17 63.3 0.1 3e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KEG14622.1 - 1.2e-11 44.6 5.1 7.8e-06 26.2 0.7 3.4 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG14622.1 - 1e-07 31.6 2.0 6.3e-07 29.1 0.6 2.7 3 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 KEG14622.1 - 0.037 14.1 2.9 3.3 8.0 0.4 3.4 3 0 0 3 3 3 0 Leucine Rich repeat DUF3328 PF11807.8 KEG14622.1 - 0.16 11.7 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) LRR_1 PF00560.33 KEG14622.1 - 0.24 12.1 5.3 1.2e+02 3.9 0.2 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat NAD_Gly3P_dh_N PF01210.23 KEG14623.1 - 4.3e-07 30.0 0.0 1.4e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KEG14623.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_C PF07479.14 KEG14623.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KEG14623.1 - 0.11 13.1 0.1 0.48 11.0 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M1 PF01433.20 KEG14624.1 - 2.4e-64 216.9 0.0 3.5e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KEG14624.1 - 1.3e-32 113.6 0.0 1.8e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KEG14624.1 - 1.7e-18 67.5 0.1 2.6e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1_N PF17900.1 KEG14625.1 - 5.1e-05 23.5 0.1 5.7e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Troponin PF00992.20 KEG14626.1 - 0.0058 16.9 2.0 0.0058 16.9 2.0 3.3 3 0 0 3 3 3 1 Troponin UPF0242 PF06785.11 KEG14626.1 - 0.0067 16.5 21.9 0.19 11.8 2.4 3.3 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 KEG14626.1 - 0.23 11.9 2.3 1.4 9.4 2.3 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) YabA PF06156.13 KEG14626.1 - 0.27 11.9 19.4 0.13 12.9 1.5 3.7 3 0 0 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 KEG14626.1 - 0.5 10.8 24.7 0.26 11.7 13.6 3.0 2 1 1 3 3 3 0 Fez1 BRE1 PF08647.11 KEG14626.1 - 5 7.3 20.0 3.4 7.8 2.9 3.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase KLRAQ PF10205.9 KEG14626.1 - 7 7.0 18.5 0.35 11.1 2.1 3.0 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein SLD5_C PF16922.5 KEG14627.1 - 1.3e-10 41.3 0.3 2.1e-10 40.6 0.3 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KEG14627.1 - 0.00034 21.0 0.0 0.00058 20.3 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Acyltransferase PF01553.21 KEG14629.1 - 3.9e-14 52.4 0.0 6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase UCH PF00443.29 KEG14631.1 - 3.4e-46 157.8 0.0 4.6e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KEG14631.1 - 3.7e-19 68.2 10.3 1.6e-17 63.0 4.6 2.9 2 0 0 2 2 2 2 Variant UBP zinc finger UCH_1 PF13423.6 KEG14631.1 - 3.7e-16 59.6 0.6 1.9e-15 57.3 0.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KEG14631.1 - 9.4e-16 57.9 3.5 9.4e-16 57.9 3.5 3.5 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 KEG14631.1 - 1.4e-06 28.1 0.4 2.9e-06 27.0 0.4 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ECH_1 PF00378.20 KEG14632.1 - 5.9e-79 264.9 1.6 6.5e-79 264.8 1.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEG14632.1 - 1.9e-38 132.8 2.2 1.9e-35 122.9 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KEG14632.1 - 0.00044 20.2 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 KEG14632.1 - 0.059 12.4 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF5329 PF17263.2 KEG14632.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5329) Pkinase PF00069.25 KEG14633.1 - 8.4e-55 186.0 0.0 1.1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14633.1 - 1.2e-32 113.2 0.0 1.8e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG14633.1 - 3.5e-05 22.8 0.0 5.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG14633.1 - 9.2e-05 21.9 0.0 0.0004 19.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEG14633.1 - 0.00042 20.3 0.0 0.22 11.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG14633.1 - 0.0061 15.5 0.0 0.055 12.4 0.0 2.0 1 1 1 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KEG14633.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIN_8 PF18476.1 KEG14635.1 - 0.0067 16.3 1.4 0.079 12.8 0.0 2.2 2 0 0 2 2 2 2 PIN like domain NAP PF00956.18 KEG14636.1 - 5.9e-05 22.4 1.6 1.5 7.9 0.1 3.1 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) COQ7 PF03232.13 KEG14637.1 - 1.4e-55 187.7 2.8 1.6e-55 187.6 2.8 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Sec39 PF08314.11 KEG14637.1 - 0.015 13.8 0.1 0.017 13.6 0.1 1.0 1 0 0 1 1 1 0 Secretory pathway protein Sec39 PTH2 PF01981.16 KEG14637.1 - 0.047 14.0 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Tom5 PF10642.9 KEG14639.1 - 0.02 14.9 1.9 0.05 13.7 0.6 2.2 1 1 1 2 2 2 0 Mitochondrial import receptor subunit or translocase COG4 PF08318.12 KEG14639.1 - 0.038 13.1 0.0 0.043 12.9 0.0 1.0 1 0 0 1 1 1 0 COG4 transport protein AAA_16 PF13191.6 KEG14640.1 - 0.0002 21.8 0.3 0.00076 19.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEG14640.1 - 0.00033 21.0 0.1 0.0032 17.7 0.0 2.5 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 KEG14640.1 - 0.0043 17.0 0.1 0.068 13.1 0.1 2.6 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KEG14640.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 KEG14640.1 - 0.0063 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_18 PF13238.6 KEG14640.1 - 0.0066 17.0 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Glyco_transf_4 PF13439.6 KEG14640.1 - 0.0098 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 AAA_30 PF13604.6 KEG14640.1 - 0.029 14.1 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEG14640.1 - 0.033 14.5 0.3 0.15 12.4 0.0 2.0 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 KEG14640.1 - 0.041 12.9 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 KEG14640.1 - 0.042 13.9 0.1 0.062 13.3 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Bac_DnaA PF00308.18 KEG14640.1 - 0.042 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATP-synt_ab PF00006.25 KEG14640.1 - 0.045 13.4 0.0 0.071 12.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.6 KEG14640.1 - 0.054 13.3 1.8 4.1 7.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KEG14640.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KEG14640.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KEG14640.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEG14640.1 - 0.096 12.3 0.5 2.2 7.8 0.5 2.6 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KEG14640.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KEG14640.1 - 0.14 12.0 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase MeaB PF03308.16 KEG14640.1 - 0.14 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NFACT-R_1 PF05670.13 KEG14641.1 - 2.5e-44 150.4 0.4 5.1e-44 149.4 0.0 1.6 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 KEG14641.1 - 0.027 14.7 0.2 0.088 13.0 0.0 2.0 2 1 1 3 3 3 0 NFACT protein RNA binding domain Saf-Nte_pilin PF09460.10 KEG14641.1 - 0.21 11.6 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Hepar_II_III PF07940.13 KEG14642.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Heparinase II/III-like protein Cytochrom_B561 PF03188.16 KEG14643.1 - 8.6e-07 29.2 9.7 8.6e-07 29.2 9.7 2.1 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4407 PF14362.6 KEG14643.1 - 1 8.6 2.9 1.8 7.9 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vma12 PF11712.8 KEG14643.1 - 4.2 7.4 8.6 0.71 9.9 1.3 2.3 1 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_C2 PF00648.21 KEG14644.1 - 1.7e-35 122.5 0.7 6.5e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 KEG14644.1 - 8.5e-09 35.8 0.0 7.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Calpain large subunit, domain III Mannosyl_trans PF05007.13 KEG14646.1 - 1.7e-88 296.9 16.2 2.3e-88 296.4 16.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KEG14646.1 - 1.2e-07 31.1 22.8 1.7e-07 30.6 22.8 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KEG14646.1 - 0.00011 22.0 17.7 0.00011 22.0 17.7 2.8 1 1 1 2 2 2 1 Glycosyltransferase family 87 IFT20 PF14931.6 KEG14647.1 - 2.3e-35 121.4 9.3 2.6e-35 121.2 9.3 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Goodbye PF17109.5 KEG14647.1 - 0.03 14.8 2.4 0.11 12.9 0.1 2.0 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain CsbD PF05532.12 KEG14647.1 - 0.087 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 CsbD-like PC_rep PF01851.22 KEG14648.1 - 0.55 10.8 12.0 3.7 8.2 0.3 5.3 5 0 0 5 5 5 0 Proteasome/cyclosome repeat zf-C2H2_2 PF12756.7 KEG14651.1 - 4.8e-15 55.7 3.5 8e-11 42.2 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) C1_2 PF03107.16 KEG14651.1 - 0.12 12.7 2.7 5.2 7.5 0.3 2.8 2 0 0 2 2 2 0 C1 domain zf-C2H2 PF00096.26 KEG14651.1 - 4.2 8.0 6.7 2.3 8.8 0.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type BILBO1_N PF18281.1 KEG14652.1 - 8.4e-22 77.4 0.1 1.6e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 BILBO1 N-terminal domain DUF3349 PF11829.8 KEG14653.1 - 0.01 16.6 3.5 0.027 15.2 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) PseudoU_synth_2 PF00849.22 KEG14654.1 - 1.1e-18 67.8 0.0 1.7e-09 37.9 0.1 2.5 2 1 0 2 2 2 2 RNA pseudouridylate synthase DUF2740 PF10872.8 KEG14655.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) AAA_18 PF13238.6 KEG14657.1 - 4.1e-28 98.5 0.2 5.5e-28 98.1 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEG14657.1 - 1.2e-07 32.2 0.7 5.7e-07 30.0 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEG14657.1 - 2.5e-05 24.5 0.3 0.017 15.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA PF00004.29 KEG14657.1 - 4.2e-05 24.0 0.0 8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEG14657.1 - 0.00016 22.0 2.3 0.00061 20.1 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KEG14657.1 - 0.00019 21.7 0.0 0.00052 20.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KEG14657.1 - 0.0013 18.7 0.2 0.0039 17.1 0.1 1.5 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KEG14657.1 - 0.0016 18.9 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KEG14657.1 - 0.0017 18.7 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 KEG14657.1 - 0.0032 17.2 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 KEG14657.1 - 0.0034 17.3 1.4 0.73 9.6 0.2 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase AAA_5 PF07728.14 KEG14657.1 - 0.0036 17.3 0.6 0.04 13.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KEG14657.1 - 0.005 16.8 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.27 KEG14657.1 - 0.0086 16.6 0.1 0.015 15.8 0.1 1.7 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 KEG14657.1 - 0.0087 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KEG14657.1 - 0.0097 15.6 0.3 0.021 14.5 0.2 1.7 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KEG14657.1 - 0.012 14.8 0.0 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KEG14657.1 - 0.014 15.8 0.6 0.03 14.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain DUF5028 PF16431.5 KEG14657.1 - 0.018 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) KTI12 PF08433.10 KEG14657.1 - 0.02 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase PF06745.13 KEG14657.1 - 0.022 14.1 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 KEG14657.1 - 0.028 13.7 0.0 0.03 13.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ADK PF00406.22 KEG14657.1 - 0.03 14.4 0.0 0.44 10.6 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.21 KEG14657.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEG14657.1 - 0.035 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 KEG14657.1 - 0.039 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.13 KEG14657.1 - 0.045 13.0 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain T2SSE PF00437.20 KEG14657.1 - 0.045 12.8 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 KEG14657.1 - 0.06 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KEG14657.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEG14657.1 - 0.084 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KEG14657.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.17 KEG14657.1 - 0.095 12.4 0.4 3.5 7.3 0.1 2.3 2 1 0 2 2 2 0 Thymidylate kinase cobW PF02492.19 KEG14657.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KEG14657.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Torsin PF06309.11 KEG14657.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Sigma54_activ_2 PF14532.6 KEG14657.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain OrsD PF12013.8 KEG14658.1 - 0.026 14.9 2.2 0.032 14.7 1.9 1.3 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D BBS1 PF14779.6 KEG14660.1 - 0.039 13.4 1.4 1.9 7.8 0.3 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Macoilin PF09726.9 KEG14661.1 - 0.38 9.3 5.3 0.52 8.8 5.3 1.2 1 0 0 1 1 1 0 Macoilin family DUF966 PF06136.13 KEG14661.1 - 1.2 8.8 12.9 0.038 13.7 5.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) CDC45 PF02724.14 KEG14661.1 - 2.6 6.2 10.2 3.9 5.6 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KEG14661.1 - 2.8 6.9 9.9 0.065 12.3 3.4 1.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF3449 PF11931.8 KEG14662.1 - 2.8e-40 138.1 0.8 5.6e-40 137.1 0.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KEG14662.1 - 1.9e-11 44.3 0.1 7.4e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 HMG_box PF00505.19 KEG14663.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.1 3 1 1 4 4 4 0 HMG (high mobility group) box TMEM51 PF15345.6 KEG14663.1 - 0.48 10.2 6.8 0.56 10.0 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3106 PF11304.8 KEG14663.1 - 4.7 7.7 13.1 5.1 7.6 8.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1353 PF07087.11 KEG14664.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) PRKCSH_1 PF13015.6 KEG14664.1 - 0.16 11.7 2.8 0.26 11.0 0.2 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Taxilin PF09728.9 KEG14665.1 - 5.7e-11 42.2 41.7 7.8e-11 41.7 41.7 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1948 PF09185.10 KEG14665.1 - 0.014 15.3 3.3 0.017 15.0 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1948) NPV_P10 PF05531.12 KEG14665.1 - 4.9 7.7 8.0 17 6.0 0.2 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KEG14665.1 - 9.7 6.5 7.5 51 4.2 0.1 3.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Adenylsucc_synt PF00709.21 KEG14665.1 - 9.9 5.0 12.8 1.2 8.0 8.2 1.7 1 1 0 2 2 2 0 Adenylosuccinate synthetase TMEM220 PF15071.6 KEG14666.1 - 0.037 14.8 2.8 0.099 13.4 1.2 2.5 2 0 0 2 2 2 0 Transmembrane family 220, helix CbiQ PF02361.16 KEG14666.1 - 0.21 11.1 5.6 0.61 9.7 5.6 1.7 1 0 0 1 1 1 0 Cobalt transport protein LmjF365940-deam PF14421.6 KEG14667.1 - 6.3e-41 140.1 0.0 7.8e-20 71.3 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-CCCH_4 PF18044.1 KEG14667.1 - 0.0038 17.0 1.8 0.012 15.5 1.8 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG14667.1 - 0.016 15.3 0.9 0.059 13.5 0.9 2.1 1 0 0 1 1 1 0 Zinc finger domain MMPL PF03176.15 KEG14668.1 - 4.4e-57 193.5 16.6 3.6e-33 114.9 2.4 2.4 2 0 0 2 2 2 2 MMPL family DUF5567 PF17722.1 KEG14669.1 - 0.00011 22.2 0.2 0.036 13.9 0.1 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5567) Tmemb_185A PF10269.9 KEG14670.1 - 7.3e-06 25.8 13.5 0.00093 18.9 8.9 2.2 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Otopetrin PF03189.13 KEG14670.1 - 0.012 14.4 2.0 0.051 12.4 0.2 2.1 2 0 0 2 2 2 0 Otopetrin DnaJ PF00226.31 KEG14670.1 - 0.089 12.9 1.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 DnaJ domain Serglycin PF04360.12 KEG14670.1 - 0.29 11.1 2.2 0.6 10.1 2.2 1.4 1 0 0 1 1 1 0 Serglycin Sigma_reg_N PF13800.6 KEG14670.1 - 4 7.8 0.0 4 7.8 0.0 3.0 3 1 1 4 4 4 0 Sigma factor regulator N-terminal SpoV PF08183.11 KEG14671.1 - 4.5e-05 23.3 0.0 8.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Stage V sporulation protein family TFIIA PF03153.13 KEG14671.1 - 0.086 12.8 35.4 0.0073 16.3 25.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.12 KEG14672.1 - 0.0014 18.7 4.8 0.078 13.0 0.0 4.7 5 1 1 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 KEG14672.1 - 3.8 6.0 16.3 0.031 12.9 2.2 2.8 3 0 0 3 3 3 0 Flagellar Assembly Protein A OTU PF02338.19 KEG14674.1 - 4.1e-07 30.5 0.0 6.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease FAP206 PF12018.8 KEG14677.1 - 3.2e-14 53.1 11.6 3.7e-05 23.4 0.0 5.5 5 0 0 5 5 5 3 Domain of unknown function YHS PF04945.13 KEG14677.1 - 3.7e-14 52.6 0.5 0.0014 18.7 0.0 4.6 4 0 0 4 4 4 3 YHS domain ADK PF00406.22 KEG14677.1 - 2e-06 28.0 0.7 0.00039 20.6 1.0 3.5 2 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 KEG14677.1 - 2.1e-05 24.7 0.0 0.059 13.5 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEG14677.1 - 0.0021 18.6 0.0 0.0021 18.6 0.0 5.3 4 2 1 5 5 4 1 AAA domain AAA_17 PF13207.6 KEG14677.1 - 0.0052 17.2 0.0 0.0052 17.2 0.0 4.6 3 1 1 4 4 4 1 AAA domain AAA PF00004.29 KEG14677.1 - 0.023 15.1 0.0 0.27 11.7 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEG14677.1 - 0.27 11.1 4.0 3.3 7.5 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Hydin_ADK PF17213.3 KEG14677.1 - 0.29 11.4 0.0 0.29 11.4 0.0 4.9 5 0 0 5 5 5 0 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 KEG14677.1 - 0.52 10.5 12.7 0.052 13.8 0.5 4.5 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.6 KEG14677.1 - 0.84 10.0 18.6 6 7.2 0.0 5.1 4 1 0 4 4 4 0 AAA ATPase domain RabGAP-TBC PF00566.18 KEG14678.1 - 3.7e-59 200.0 0.0 4.8e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TBX PF12598.8 KEG14678.1 - 0.34 11.7 1.9 0.64 10.9 1.9 1.3 1 0 0 1 1 1 0 T-box transcription factor RabGAP-TBC PF00566.18 KEG14680.1 - 3.9e-55 186.8 0.1 5.6e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ArgoL1 PF08699.10 KEG14680.1 - 0.17 11.6 0.0 0.52 10.0 0.0 1.8 1 0 0 1 1 1 0 Argonaute linker 1 domain TPR_19 PF14559.6 KEG14681.1 - 0.1 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CBM9_1 PF06452.11 KEG14681.1 - 0.19 11.6 0.2 0.33 10.8 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate family 9 binding domain-like ABC1 PF03109.16 KEG14682.1 - 3.4e-28 98.2 0.0 6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KEG14682.1 - 1.8e-08 34.1 0.2 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14682.1 - 2.6e-06 26.9 0.1 0.0085 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KEG14682.1 - 6.6e-05 22.9 1.6 0.00016 21.7 1.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEG14682.1 - 0.0013 18.3 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KEG14682.1 - 0.0016 17.8 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_19 PF14559.6 KEG14683.1 - 1.8e-06 28.3 6.5 0.13 12.7 0.0 6.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14683.1 - 0.0002 21.2 3.9 0.16 12.2 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14683.1 - 0.00085 19.9 0.2 3.1 8.5 0.8 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG14683.1 - 0.0021 18.3 2.8 5.4 7.3 0.2 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KEG14683.1 - 0.0041 17.8 9.2 0.33 11.9 0.0 5.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14683.1 - 0.0043 16.8 0.3 0.22 11.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14683.1 - 0.042 14.1 0.1 17 5.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG14683.1 - 0.072 13.8 7.3 46 4.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Neuraminidase PF18413.1 KEG14683.1 - 0.08 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Neuraminidase-like domain TPR_4 PF07721.14 KEG14683.1 - 0.94 10.3 15.2 4.3 8.3 2.7 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 KEG14684.1 - 1.2e-14 54.4 0.2 3e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG14684.1 - 5.7e-09 34.9 0.7 0.0041 16.6 0.0 4.6 5 1 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KEG14684.1 - 4.4e-08 32.4 0.0 0.0013 18.5 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KEG14684.1 - 3.1e-06 26.9 0.4 0.00061 19.6 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 KEG14684.1 - 0.00052 20.1 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 KEG14684.1 - 0.0054 16.2 0.1 0.14 11.7 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KEG14684.1 - 0.023 15.0 0.1 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain PHB_acc_N PF07879.11 KEG14684.1 - 0.18 11.9 0.4 6.8 6.9 0.0 2.7 2 1 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain RNA_pol_Rpc34 PF05158.12 KEG14685.1 - 7e-65 219.6 0.0 8.1e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_20 PF12840.7 KEG14685.1 - 0.00063 19.7 1.6 0.47 10.6 0.7 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_36 PF13730.6 KEG14685.1 - 0.0011 18.8 0.4 0.21 11.6 0.1 3.0 3 1 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.7 KEG14685.1 - 0.002 18.0 7.0 0.071 13.0 1.2 2.9 3 0 0 3 3 3 2 MarR family RPA_C PF08784.11 KEG14685.1 - 0.0042 17.7 0.1 5.9 7.6 0.1 3.0 3 0 0 3 3 3 1 Replication protein A C terminal z-alpha PF02295.17 KEG14685.1 - 0.0056 16.7 0.1 1.7 8.7 0.1 2.2 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain HTH_27 PF13463.6 KEG14685.1 - 0.014 15.9 0.2 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 Winged helix DNA-binding domain TrmB PF01978.19 KEG14685.1 - 0.026 14.4 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Tn7_Tnp_TnsA_C PF08721.11 KEG14685.1 - 0.033 14.8 0.0 19 6.0 0.0 2.9 3 0 0 3 3 3 0 TnsA endonuclease C terminal HTH_32 PF13565.6 KEG14685.1 - 0.045 14.4 0.1 0.1 13.2 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Stork_head PF10264.9 KEG14685.1 - 0.051 13.7 0.4 2.3 8.5 0.1 3.0 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain FeoC PF09012.10 KEG14685.1 - 0.17 11.9 0.7 0.97 9.5 0.2 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator Rrf2 PF02082.20 KEG14685.1 - 0.81 10.1 2.8 2.9 8.3 0.1 2.6 3 0 0 3 3 3 0 Transcriptional regulator Carn_acyltransf PF00755.20 KEG14686.1 - 1.4e-141 473.1 0.0 1.6e-141 472.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase T2SSM PF04612.12 KEG14686.1 - 0.054 13.5 2.3 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DSS1_SEM1 PF05160.13 KEG14688.1 - 0.00025 21.0 3.3 0.00036 20.5 1.2 2.0 2 0 0 2 2 2 1 DSS1/SEM1 family Lipase_3 PF01764.25 KEG14689.1 - 4.6e-28 97.9 0.0 1.3e-27 96.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 KEG14689.1 - 5.6e-05 22.5 38.4 0.0016 17.7 33.9 2.7 2 1 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF2974 PF11187.8 KEG14689.1 - 0.0045 16.6 0.0 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF1849 PF08904.11 KEG14690.1 - 0.054 13.0 0.0 0.066 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Lipase_3 PF01764.25 KEG14691.1 - 1.1e-24 86.9 0.0 2.4e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KEG14691.1 - 0.045 13.3 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3341 PF11821.8 KEG14691.1 - 0.94 9.1 4.0 1.8 8.2 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) Sec16_C PF12931.7 KEG14692.1 - 2.3e-21 76.8 0.0 3.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DUF572 PF04502.13 KEG14693.1 - 6.4e-22 78.6 12.5 8e-22 78.3 12.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3073 PF11273.8 KEG14693.1 - 0.36 11.6 0.2 0.36 11.6 0.2 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3073) LptF_LptG PF03739.14 KEG14693.1 - 0.61 8.9 2.6 0.87 8.4 2.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Pex26 PF07163.12 KEG14693.1 - 8.1 5.6 7.9 7.4 5.8 5.5 2.0 1 1 1 2 2 2 0 Pex26 protein PIEZO PF15917.5 KEG14693.1 - 8.9 5.7 20.0 4.9 6.6 16.0 2.0 2 0 0 2 2 2 0 Piezo zf-BED PF02892.15 KEG14693.1 - 9.9 6.3 7.7 0.69 10.0 0.1 2.7 3 0 0 3 3 3 0 BED zinc finger DUF2909 PF11137.8 KEG14695.1 - 7.2 6.6 9.7 0.28 11.1 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) Metallophos PF00149.28 KEG14696.1 - 4.4e-14 53.4 0.0 6.3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEG14696.1 - 2.2e-06 27.9 0.0 3.8e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 KEG14696.1 - 0.098 11.7 0.0 6.2 5.7 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase BatD PF13584.6 KEG14696.1 - 0.12 11.2 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Oxygen tolerance SKG6 PF08693.10 KEG14696.1 - 0.25 10.8 3.0 0.54 9.7 3.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EI24 PF07264.11 KEG14697.1 - 4.2e-13 49.9 23.5 4.9e-13 49.7 22.6 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Thioredoxin_8 PF13905.6 KEG14698.1 - 4.8e-05 23.6 0.0 0.66 10.3 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Pan_kinase PF03309.14 KEG14698.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Type III pantothenate kinase Cwf_Cwc_15 PF04889.12 KEG14698.1 - 1.3 8.7 16.8 1.4 8.6 2.1 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EF-hand_7 PF13499.6 KEG14699.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Thioredoxin_8 PF13905.6 KEG14700.1 - 2.4e-26 91.9 0.0 3.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KEG14700.1 - 3.8e-10 39.6 0.0 4.7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 KEG14700.1 - 2.6e-09 37.0 0.0 5.2e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin TraF PF13728.6 KEG14700.1 - 7.2e-09 35.8 0.0 2.5e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KEG14700.1 - 1.8e-08 34.8 0.0 2.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KEG14700.1 - 2.8e-08 33.7 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KEG14700.1 - 0.0019 18.0 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KEG14700.1 - 0.01 16.0 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.11 KEG14700.1 - 0.031 13.9 0.1 0.56 9.8 0.1 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 KEG14701.1 - 5.5e-20 71.5 0.0 8.1e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KEG14701.1 - 7e-10 38.8 0.0 9.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEG14701.1 - 1.1e-08 35.0 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 KEG14701.1 - 1.2e-07 31.7 0.0 7.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KEG14701.1 - 1e-06 29.1 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KEG14701.1 - 3.9e-05 23.7 0.0 0.0001 22.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KEG14701.1 - 0.001 18.8 0.0 0.0031 17.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 KEG14701.1 - 0.0094 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein PSP1 PF04468.12 KEG14702.1 - 1e-19 70.6 1.2 1.7e-19 69.9 1.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ank_2 PF12796.7 KEG14704.1 - 3.7e-35 120.4 1.5 1.8e-12 47.7 0.0 3.9 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG14704.1 - 2.1e-25 88.8 0.5 4.9e-10 39.7 0.0 4.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEG14704.1 - 9.4e-21 71.7 0.9 0.0083 16.6 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KEG14704.1 - 1.5e-15 56.8 0.5 0.025 15.0 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KEG14704.1 - 2.4e-15 56.4 0.6 0.0021 18.3 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ribosomal_L4 PF00573.22 KEG14705.1 - 3.1e-35 121.6 0.0 3.1e-35 121.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KEG14705.1 - 5.6e-19 68.0 4.6 5.9e-19 67.9 2.7 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DSPc PF00782.20 KEG14707.1 - 1.6e-30 105.6 0.1 2.3e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG14707.1 - 0.00065 19.3 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KEG14707.1 - 0.044 14.1 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Nitr_red_assoc PF09655.10 KEG14710.1 - 0.032 14.9 0.2 0.035 14.8 0.2 1.1 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) CEP19 PF14933.6 KEG14711.1 - 9.5e-29 100.8 0.3 1e-28 100.7 0.3 1.1 1 0 0 1 1 1 1 CEP19-like protein CEP19 PF14933.6 KEG14712.1 - 0.00014 22.2 0.0 0.00021 21.6 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.18 KEG14713.1 - 1.2e-47 162.4 0.0 1.7e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Aminotran_1_2 PF00155.21 KEG14713.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II Iwr1 PF08574.10 KEG14714.1 - 1.1 10.3 12.9 0.46 11.5 4.9 3.3 3 0 0 3 3 3 0 Transcription factor Iwr1 Tetraspanin PF00335.20 KEG14715.1 - 5e-18 65.7 9.0 6.7e-18 65.2 9.0 1.1 1 0 0 1 1 1 1 Tetraspanin family UPF0182 PF03699.13 KEG14715.1 - 0.12 10.4 2.2 0.17 10.0 2.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF2567 PF10821.8 KEG14715.1 - 2.8 8.0 8.7 0.36 10.9 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) RIF5_SNase_1 PF18187.1 KEG14716.1 - 1e-52 178.1 0.0 1.9e-52 177.2 0.0 1.5 1 0 0 1 1 1 1 TbRIF5 SNase domain 1 RIF5_SNase_2 PF18189.1 KEG14716.1 - 4.1e-48 163.1 0.1 2.9e-47 160.4 0.0 2.3 2 0 0 2 2 2 1 TbRIF5 SNase domain 2 Lung_7-TM_R PF06814.13 KEG14717.1 - 1.8e-31 109.5 10.2 2.5e-31 109.0 10.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Peptidase_M14 PF00246.24 KEG14719.1 - 6e-15 55.8 0.0 1.3e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KEG14719.1 - 4.5e-12 46.3 0.1 9.3e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KEG14719.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family TFIIA PF03153.13 KEG14719.1 - 0.44 10.5 11.0 0.057 13.4 6.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit B12D PF06522.11 KEG14720.1 - 0.81 9.5 2.1 2.3 8.1 2.1 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Metallophos PF00149.28 KEG14721.1 - 1.5e-17 64.8 1.7 2e-17 64.4 0.9 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEG14721.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 KEG14721.1 - 0.0022 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase HAP2-GCS1 PF10699.9 KEG14722.1 - 1.9e-18 66.2 0.4 3.9e-18 65.1 0.4 1.6 1 0 0 1 1 1 1 Male gamete fusion factor UPF0257 PF06788.13 KEG14723.1 - 0.057 13.2 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) DHHC PF01529.20 KEG14724.1 - 1.8e-35 122.0 6.9 1.8e-35 122.0 6.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.13 KEG14724.1 - 2.1 8.6 4.2 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus A_deamin PF02137.18 KEG14727.1 - 7.9e-24 84.7 0.0 4.6e-23 82.2 0.0 2.3 2 1 0 2 2 2 1 Adenosine-deaminase (editase) domain DUF2650 PF10853.8 KEG14727.1 - 0.85 9.4 8.5 2.2 8.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) GST_C_5 PF16865.5 KEG14728.1 - 1.8e-76 253.6 1.0 1e-44 151.5 0.1 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEG14728.1 - 1.3e-29 102.4 0.2 6.5e-16 58.5 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEG14728.1 - 3.3e-26 91.4 0.2 3.9e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEG14728.1 - 3.7e-20 71.7 1.0 8.3e-10 38.6 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEG14728.1 - 1.1e-16 60.9 0.1 6.3e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEG14728.1 - 5.1e-10 39.4 0.1 2.7e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KEG14728.1 - 5.5e-08 32.9 0.5 7.9e-07 29.2 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 KEG14728.1 - 6.8e-07 29.4 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KEG14728.1 - 0.0011 19.3 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KEG14728.1 - 0.088 13.6 0.0 6.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KEG14728.1 - 0.14 12.4 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein RRM_1 PF00076.22 KEG14730.1 - 1.8e-10 40.5 0.0 2.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEG14730.1 - 2.9e-05 24.0 0.1 5.6e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 KEG14730.1 - 0.023 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 KEG14730.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif GTA_holin_3TM PF11351.8 KEG14730.1 - 0.2 12.2 1.9 0.24 11.9 0.2 1.8 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release EIF_2_alpha PF07541.12 KEG14731.1 - 6e-19 68.3 0.0 2.1e-18 66.5 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KEG14731.1 - 1.2e-11 44.7 2.1 3.6e-11 43.2 1.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 KEG14731.1 - 0.0014 19.2 1.4 0.0049 17.5 0.2 2.3 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 Pkinase PF00069.25 KEG14732.1 - 1e-15 57.8 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14732.1 - 0.00036 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase MORN PF02493.20 KEG14733.1 - 4.7e-21 73.3 38.8 8.4e-06 25.4 4.8 7.6 7 1 0 7 7 7 6 MORN repeat Cu-oxidase_2 PF07731.14 KEG14735.1 - 5.3e-20 71.6 0.3 2.2e-19 69.6 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEG14735.1 - 4.5e-09 36.3 1.4 7.4e-05 22.7 0.2 4.1 4 1 1 5 5 5 3 Multicopper oxidase Snapin_Pallidin PF14712.6 KEG14738.1 - 3.2e-07 30.7 1.5 6.6e-07 29.7 1.5 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Golgin_A5 PF09787.9 KEG14738.1 - 0.0031 17.0 3.9 0.0038 16.7 3.9 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 ATG16 PF08614.11 KEG14738.1 - 0.0034 17.6 3.8 0.0045 17.2 3.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KEG14738.1 - 0.0052 16.9 3.5 0.0084 16.2 3.5 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.6 KEG14738.1 - 0.0057 16.3 0.8 0.0064 16.1 0.8 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus ADIP PF11559.8 KEG14738.1 - 0.0066 16.5 4.2 0.0091 16.1 4.2 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding BST2 PF16716.5 KEG14738.1 - 0.027 15.0 3.5 1.1 9.9 0.0 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 KEG14738.1 - 0.062 12.2 3.0 0.077 11.9 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein WASH_WAHD PF11945.8 KEG14738.1 - 0.071 12.6 0.4 0.088 12.3 0.4 1.1 1 0 0 1 1 1 0 WAHD domain of WASH complex Prominin PF05478.11 KEG14738.1 - 0.073 11.0 1.0 0.087 10.8 1.0 1.0 1 0 0 1 1 1 0 Prominin KxDL PF10241.9 KEG14738.1 - 0.078 13.3 5.1 0.063 13.6 3.1 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 KEG14738.1 - 0.084 12.4 2.5 0.098 12.2 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NAD_binding_1 PF00175.21 KEG14738.1 - 0.13 13.0 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain T7SS_ESX_EspC PF10824.8 KEG14738.1 - 0.16 12.4 0.3 0.16 12.4 0.3 2.0 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Nup54 PF13874.6 KEG14738.1 - 0.29 11.2 6.7 0.5 10.5 6.7 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HIP1_clath_bdg PF16515.5 KEG14738.1 - 0.35 11.5 7.3 1.1 9.9 6.5 2.0 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rx_N PF18052.1 KEG14738.1 - 0.46 10.8 5.5 0.31 11.4 0.4 2.2 1 1 1 2 2 2 0 Rx N-terminal domain Bcr-Abl_Oligo PF09036.10 KEG14738.1 - 0.53 10.3 3.6 2.3 8.3 1.3 2.2 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain FOXP-CC PF16159.5 KEG14738.1 - 1 10.1 5.0 0.71 10.5 1.0 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain DHR10 PF18595.1 KEG14738.1 - 1.9 8.6 12.8 1.3 9.1 1.7 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Amidohydro_3 PF07969.11 KEG14739.1 - 3.8e-65 221.2 0.0 5.1e-64 217.5 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KEG14739.1 - 4.6e-17 62.4 0.1 3e-13 49.8 0.1 2.8 2 1 0 2 2 2 2 Amidohydrolase family LSM PF01423.22 KEG14740.1 - 1.9e-10 40.3 0.2 2.8e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 LSM domain Mut7-C PF01927.16 KEG14741.1 - 1e-34 119.8 1.6 2.3e-33 115.4 1.6 2.0 1 1 0 1 1 1 1 Mut7-C RNAse domain dCache_3 PF14827.6 KEG14741.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase UQ_con PF00179.26 KEG14742.1 - 7.9e-33 113.1 0.0 1e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEG14742.1 - 0.056 13.7 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain S4 PF01479.25 KEG14743.1 - 5.6e-07 29.2 0.1 1.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KEG14743.1 - 0.0056 17.6 0.5 0.0056 17.6 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L22e PF01776.17 KEG14743.1 - 0.044 14.2 0.1 0.47 10.8 0.2 2.3 2 0 0 2 2 2 0 Ribosomal L22e protein family Kinesin PF00225.23 KEG14744.1 - 2.3e-101 339.1 0.1 2.3e-101 339.1 0.1 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG14744.1 - 2.7e-27 95.5 0.0 2.7e-27 95.5 0.0 4.1 3 2 0 3 3 3 1 Microtubule binding Imm61 PF15598.6 KEG14744.1 - 0.053 13.4 0.7 8.2 6.3 0.0 3.0 2 0 0 2 2 2 0 Immunity protein 61 AAA_16 PF13191.6 KEG14744.1 - 2.1 8.7 0.0 2.1 8.7 0.0 4.7 4 1 0 4 4 4 0 AAA ATPase domain EF-hand_6 PF13405.6 KEG14746.1 - 2.1e-11 42.8 0.3 0.0031 17.3 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 KEG14746.1 - 3e-09 37.2 0.5 0.00083 19.8 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG14746.1 - 1.1e-08 34.0 0.3 0.46 10.2 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KEG14746.1 - 5.9e-06 26.0 1.5 0.41 10.5 0.0 4.2 3 1 1 4 4 4 2 EF-hand domain pair AKAP7_NLS PF10469.9 KEG14747.1 - 7.1e-36 124.0 0.0 8.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KEG14747.1 - 9.3e-10 38.6 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KEG14747.1 - 0.0012 19.0 0.0 0.1 12.8 0.1 2.4 2 0 0 2 2 2 1 LigT like Phosphoesterase DSPc PF00782.20 KEG14748.1 - 8.6e-14 51.5 0.0 2e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEG14748.1 - 3.4e-13 49.7 0.0 1.1e-12 48.0 0.1 1.8 1 1 1 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KEG14748.1 - 8.5e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KEG14748.1 - 2.7e-05 24.3 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KEG14748.1 - 0.0033 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family AMMECR1 PF01871.17 KEG14749.1 - 4.2e-52 176.1 0.0 4.9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 MgtE PF01769.16 KEG14750.1 - 1.6e-19 70.5 2.7 1.6e-19 70.5 2.7 1.9 1 1 1 2 2 2 1 Divalent cation transporter DUF3792 PF12670.7 KEG14750.1 - 6.3 7.0 16.1 2.1 8.5 3.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) WD40 PF00400.32 KEG14752.1 - 1.1e-07 32.4 5.0 0.59 11.1 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat YqzH PF14164.6 KEG14753.1 - 0.044 13.9 0.1 0.97 9.6 0.1 2.7 2 0 0 2 2 2 0 YqzH-like protein Amidohydro_1 PF01979.20 KEG14753.1 - 0.16 11.3 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase family PspB PF06667.12 KEG14753.1 - 0.51 10.4 2.0 1.3 9.1 2.0 1.7 1 0 0 1 1 1 0 Phage shock protein B DnaJ PF00226.31 KEG14754.1 - 7.2e-08 32.4 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF713 PF05218.14 KEG14754.1 - 0.034 13.9 2.7 0.5 10.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF713) TMCO5 PF14992.6 KEG14754.1 - 0.15 11.6 3.5 0.4 10.2 0.6 2.2 2 1 0 2 2 2 0 TMCO5 family CoatB PF10389.9 KEG14754.1 - 3.7 7.5 5.0 7.1 6.6 5.0 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B DEAD PF00270.29 KEG14756.1 - 4.4e-35 121.0 0.1 1.2e-34 119.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG14756.1 - 1.3e-29 102.8 0.1 4e-29 101.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG14756.1 - 4.3e-06 26.8 0.0 1.3e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KEG14756.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain CHCH PF06747.13 KEG14757.1 - 5.3e-06 26.4 10.2 0.0076 16.4 0.3 3.5 4 0 0 4 4 4 3 CHCH domain CX9C PF16860.5 KEG14757.1 - 0.0018 18.3 2.9 0.58 10.2 0.0 3.3 2 1 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 KEG14757.1 - 0.012 15.8 1.7 0.012 15.8 1.7 2.4 2 1 0 2 2 2 0 Mature-T-Cell Proliferation I type NDUF_B7 PF05676.13 KEG14757.1 - 0.13 12.0 8.6 2.4 7.9 1.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KEG14757.1 - 0.25 11.7 3.8 0.77 10.1 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 KEG14757.1 - 1.8 8.9 5.8 2.3 8.5 0.2 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) TauE PF01925.19 KEG14758.1 - 6.4e-19 68.5 28.0 7.5e-13 48.7 5.2 2.2 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Profilin PF00235.19 KEG14760.1 - 1.1e-36 126.0 0.4 1.3e-36 125.6 0.4 1.1 1 0 0 1 1 1 1 Profilin CDC50 PF03381.15 KEG14761.1 - 1.8e-62 211.4 0.0 2.2e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Ras PF00071.22 KEG14763.1 - 9e-58 194.4 0.1 1.1e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG14763.1 - 6e-36 123.3 0.1 9.7e-36 122.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG14763.1 - 6e-15 55.1 0.0 7.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG14763.1 - 1.3e-05 25.2 0.0 2.6e-05 24.3 0.0 1.5 2 0 0 2 2 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEG14763.1 - 2.2e-05 24.0 0.0 3.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEG14763.1 - 2.5e-05 23.9 0.1 0.00039 20.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KEG14763.1 - 0.0026 18.2 0.1 0.0048 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KEG14763.1 - 0.0037 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Septin YwhD PF08741.10 KEG14763.1 - 0.0041 16.8 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 YwhD family AAA_7 PF12775.7 KEG14763.1 - 0.0044 16.5 0.1 0.0069 15.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KEG14763.1 - 0.0045 16.9 0.1 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KEG14763.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KEG14763.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein SRPRB PF09439.10 KEG14763.1 - 0.0076 15.7 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 KEG14763.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KEG14763.1 - 0.041 14.4 0.1 0.047 14.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KEG14763.1 - 0.048 12.9 0.1 5.4 6.2 0.0 2.4 2 1 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KEG14763.1 - 0.053 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KEG14763.1 - 0.058 12.5 0.0 0.38 9.8 0.0 1.9 1 1 1 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 KEG14763.1 - 0.097 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 KEG14763.1 - 0.098 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 KEG14763.1 - 0.12 12.1 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Methyltransf_31 PF13847.6 KEG14763.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain G-alpha PF00503.20 KEG14763.1 - 0.14 11.3 0.1 0.25 10.5 0.1 1.8 1 1 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.22 KEG14763.1 - 0.15 12.5 0.0 0.48 10.8 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Acetyltransf_1 PF00583.25 KEG14765.1 - 1.6e-17 63.8 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEG14765.1 - 2.5e-14 53.3 0.0 3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEG14765.1 - 1.8e-13 50.7 0.1 2.7e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEG14765.1 - 7e-05 22.9 0.0 0.00015 21.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEG14765.1 - 9.1e-05 22.4 0.0 0.00027 20.9 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KEG14765.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KEG14765.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PRC PF05239.16 KEG14765.1 - 0.017 15.2 0.1 0.053 13.6 0.0 1.8 2 0 0 2 2 2 0 PRC-barrel domain Acetyltransf_8 PF13523.6 KEG14765.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KEG14766.1 - 1.1e-56 192.1 0.0 1.3e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14766.1 - 7.2e-39 133.6 0.0 8.9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_3 PF08239.11 KEG14766.1 - 5.4e-09 36.2 0.0 9.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Kinase-like PF14531.6 KEG14766.1 - 2.3e-05 23.8 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG14766.1 - 0.00056 18.8 0.0 0.00082 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEG14766.1 - 0.003 16.5 0.1 0.0043 16.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEG14766.1 - 0.021 14.8 0.0 0.88 9.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FHA PF00498.26 KEG14770.1 - 0.00094 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain CCDC-167 PF15188.6 KEG14770.1 - 2.4 8.6 5.0 0.94 9.9 1.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 WD40 PF00400.32 KEG14771.1 - 0.00019 22.1 16.3 0.016 16.1 0.0 5.6 5 1 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.6 KEG14771.1 - 1.1 9.8 10.0 2.1 9.0 0.1 4.3 4 2 1 5 5 5 0 PQQ-like domain zf_CCCH_4 PF18345.1 KEG14772.1 - 0.00011 22.1 9.9 0.0053 16.8 1.8 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KEG14772.1 - 0.00021 21.1 10.5 0.09 12.7 3.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KEG14772.1 - 0.0019 18.9 0.6 2.1 9.1 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KEG14772.1 - 0.019 14.8 12.2 0.14 11.9 0.6 2.7 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCHH PF10283.9 KEG14772.1 - 0.19 11.8 2.5 3.9 7.6 0.4 2.8 3 0 0 3 3 3 0 PBZ domain zf-CCCH_2 PF14608.6 KEG14772.1 - 4.3 7.9 7.0 21 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger CitMHS PF03600.16 KEG14774.1 - 4.8e-19 68.7 42.0 4.8e-19 68.7 42.0 1.9 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 KEG14774.1 - 3.6e-18 65.9 40.0 1.1e-17 64.3 40.0 2.2 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KEG14774.1 - 9.2e-08 32.4 11.2 1.1e-06 28.8 6.9 2.7 1 1 1 2 2 2 1 SPX domain Rib_recp_KP_reg PF05104.12 KEG14776.1 - 1 10.4 8.2 2.5 9.1 8.2 1.7 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Dor1 PF04124.12 KEG14777.1 - 4.4e-19 68.4 1.1 5.7e-19 68.0 1.1 1.2 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 KEG14777.1 - 0.00018 21.4 0.1 0.00053 19.9 0.0 1.7 1 1 0 1 1 1 1 Exocyst component 84 C-terminal HLH PF00010.26 KEG14777.1 - 0.03 14.3 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain AAA_6 PF12774.7 KEG14779.1 - 2.6e-150 499.9 0.0 7e-150 498.5 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG14779.1 - 3.2e-105 352.5 5.8 3.2e-105 352.5 5.8 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KEG14779.1 - 1.1e-98 329.7 0.0 5.6e-98 327.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KEG14779.1 - 4.8e-81 272.3 0.0 7.6e-80 268.4 0.0 3.1 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KEG14779.1 - 1.6e-76 256.3 0.0 3e-75 252.1 0.0 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KEG14779.1 - 6.7e-73 244.1 0.2 1.4e-66 223.4 0.0 3.8 4 0 0 4 4 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KEG14779.1 - 9.3e-55 184.9 0.0 2.2e-54 183.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEG14779.1 - 8.8e-45 151.6 0.2 2.2e-42 143.9 0.0 4.5 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KEG14779.1 - 8.6e-39 133.5 7.5 1.8e-38 132.5 7.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KEG14779.1 - 1.1e-23 83.7 0.5 6.4e-23 81.2 0.0 2.7 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KEG14779.1 - 2.9e-23 82.4 0.1 1.1e-06 28.7 0.0 6.5 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KEG14779.1 - 3.9e-12 46.3 0.0 1.4e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEG14779.1 - 1.5e-07 31.9 8.5 1.1 9.6 0.0 7.6 7 1 1 8 8 8 3 AAA ATPase domain AAA PF00004.29 KEG14779.1 - 2.3e-07 31.3 0.1 0.062 13.7 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG14779.1 - 2.3e-07 31.1 7.1 0.19 12.0 0.0 7.0 7 0 0 7 7 7 2 AAA domain RNA_helicase PF00910.22 KEG14779.1 - 0.00032 21.0 0.0 0.26 11.7 0.0 4.4 4 0 0 4 4 3 1 RNA helicase Sigma54_activat PF00158.26 KEG14779.1 - 0.00071 19.3 0.3 0.84 9.3 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_18 PF13238.6 KEG14779.1 - 0.00077 20.0 0.0 0.088 13.4 0.0 3.8 4 0 0 4 4 3 1 AAA domain GAS PF13851.6 KEG14779.1 - 0.0015 17.9 7.8 0.0015 17.9 7.8 4.7 6 0 0 6 6 4 1 Growth-arrest specific micro-tubule binding T2SSE PF00437.20 KEG14779.1 - 0.0028 16.8 0.3 4.4 6.3 0.0 4.0 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_30 PF13604.6 KEG14779.1 - 0.016 15.0 0.7 8.3 6.1 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_lid_7 PF17867.1 KEG14779.1 - 0.016 15.4 0.1 0.072 13.3 0.1 2.2 1 0 0 1 1 1 0 Midasin AAA lid domain HEPN_SAV_6107 PF18726.1 KEG14779.1 - 0.039 14.5 1.1 0.12 12.9 1.1 1.8 1 0 0 1 1 1 0 SAV_6107-like HEPN RsgA_GTPase PF03193.16 KEG14779.1 - 0.044 13.7 0.0 8.5 6.2 0.0 3.5 3 0 0 3 3 3 0 RsgA GTPase DUF853 PF05872.12 KEG14779.1 - 0.061 11.9 0.4 2.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.21 KEG14779.1 - 0.089 12.2 0.9 0.65 9.3 0.0 2.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KEG14779.1 - 0.13 12.2 0.0 27 4.6 0.0 3.5 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 KEG14779.1 - 0.16 11.6 1.1 26 4.4 0.1 3.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KEG14779.1 - 0.27 11.0 0.6 32 4.4 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KEG14779.1 - 0.4 10.8 1.8 57 3.9 0.0 4.0 4 0 0 4 4 3 0 AAA domain DUF4298 PF14131.6 KEG14779.1 - 2.1 8.4 7.3 6.7 6.8 0.2 3.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4298) Ribosomal_L14e PF01929.17 KEG14780.1 - 4.1e-16 59.2 3.6 4.1e-16 59.2 3.6 2.3 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 KEG14780.1 - 2.2e-05 24.2 0.5 3.8e-05 23.5 0.5 1.4 1 0 0 1 1 1 1 KOW motif Ldh_1_N PF00056.23 KEG14782.1 - 2.1e-33 115.4 0.2 3.6e-33 114.6 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEG14782.1 - 4.5e-28 98.3 0.0 8.9e-28 97.3 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain RmlD_sub_bind PF04321.17 KEG14782.1 - 0.023 13.8 0.3 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain LRR_8 PF13855.6 KEG14783.1 - 0.023 14.4 1.8 1.8 8.4 0.0 3.5 4 0 0 4 4 4 0 Leucine rich repeat KptA_kDCL PF18176.1 KEG14783.1 - 0.062 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain LRR_4 PF12799.7 KEG14783.1 - 0.26 11.7 0.9 20 5.8 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) SlyX PF04102.12 KEG14784.1 - 0.025 15.2 4.0 0.38 11.4 0.5 2.4 2 0 0 2 2 2 0 SlyX ATG16 PF08614.11 KEG14784.1 - 0.053 13.7 3.4 0.4 10.9 0.2 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4349 PF14257.6 KEG14784.1 - 0.06 12.8 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) KxDL PF10241.9 KEG14784.1 - 0.1 12.9 1.0 7 7.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein Cluap1 PF10234.9 KEG14784.1 - 0.12 11.8 3.3 0.17 11.2 3.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Zn_ribbon_17 PF17120.5 KEG14784.1 - 0.12 12.0 2.7 1.2 8.8 1.6 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type HrpB7 PF09486.10 KEG14784.1 - 0.13 12.7 7.5 0.99 9.8 8.1 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-RING_11 PF17123.5 KEG14784.1 - 0.16 11.8 1.8 0.35 10.6 1.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 KEG14784.1 - 0.61 10.5 7.8 6.4 7.2 7.8 2.5 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KEG14784.1 - 1.5 8.8 7.1 3.1 7.7 1.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEG14784.1 - 1.5 8.9 3.5 1 9.4 0.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KEG14784.1 - 8.3 6.4 7.8 23 5.0 2.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 IQ PF00612.27 KEG14785.1 - 0.024 14.4 5.0 3.3 7.7 0.8 3.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif HSP70 PF00012.20 KEG14786.1 - 1.8e-195 650.7 0.2 2.1e-195 650.4 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEG14786.1 - 4.8e-11 42.1 2.9 5e-10 38.7 0.4 2.7 3 0 0 3 3 3 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KEG14786.1 - 0.00063 19.3 0.2 0.047 13.2 0.0 2.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KEG14786.1 - 0.0019 18.6 0.6 0.028 14.8 0.2 3.0 2 1 0 2 2 2 1 Cell division protein FtsA AraC_N PF06719.13 KEG14786.1 - 0.054 13.2 0.3 0.054 13.2 0.3 2.1 3 0 0 3 3 3 0 AraC-type transcriptional regulator N-terminus DNA_ligase_A_N PF04675.14 KEG14786.1 - 0.084 13.2 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 DNA ligase N terminus GFRP PF06399.13 KEG14786.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.8 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Phage_TAC_11 PF11836.8 KEG14786.1 - 0.33 11.1 0.0 0.33 11.1 0.0 3.6 2 2 1 3 3 3 0 Phage tail tube protein, GTA-gp10 IHABP4_N PF16174.5 KEG14787.1 - 1 9.9 9.9 2.1 9.0 9.9 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Presenilin PF01080.17 KEG14787.1 - 5.4 5.7 6.6 6.1 5.5 6.6 1.1 1 0 0 1 1 1 0 Presenilin Beta-lactamase PF00144.24 KEG14788.1 - 5e-08 32.6 0.1 3.8e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase DUF2804 PF10974.8 KEG14789.1 - 0.0054 16.3 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) WW PF00397.26 KEG14791.1 - 0.0014 18.6 0.9 0.0027 17.8 0.9 1.4 1 0 0 1 1 1 1 WW domain Fijivirus_P9-2 PF06837.11 KEG14792.1 - 0.09 12.2 0.2 0.17 11.3 0.2 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein TPR_2 PF07719.17 KEG14794.1 - 2.3e-12 46.0 3.1 0.0032 17.5 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14794.1 - 8.9e-11 41.7 12.9 0.026 15.3 0.4 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14794.1 - 3.6e-09 36.0 0.9 0.65 9.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14794.1 - 2.1e-08 34.0 0.1 2.9e-05 24.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14794.1 - 1.8e-06 27.7 0.1 0.25 11.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG14794.1 - 4e-05 23.7 1.3 4e-05 23.7 1.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEG14794.1 - 9.4e-05 21.8 0.4 9.4e-05 21.8 0.4 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14794.1 - 0.00099 18.7 0.1 0.015 15.0 0.0 3.0 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KEG14794.1 - 0.0072 16.6 6.9 0.047 14.0 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14794.1 - 0.0075 16.8 6.1 0.023 15.2 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KEG14794.1 - 0.072 13.4 1.2 2.7 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG14794.1 - 0.46 10.6 4.9 1.1e+02 3.2 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Rubella_Capsid PF05750.11 KEG14795.1 - 0.017 14.8 1.1 0.026 14.2 1.1 1.2 1 0 0 1 1 1 0 Rubella capsid protein SYCE1 PF15233.6 KEG14795.1 - 0.3 11.1 11.0 0.25 11.4 0.9 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 GIT_CC PF16559.5 KEG14795.1 - 1 9.3 9.7 0.4 10.6 1.3 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 KEG14795.1 - 3.6 7.8 14.7 14 6.0 6.2 3.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 KEG14795.1 - 5.5 7.3 8.4 1.9 8.8 3.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ERM PF00769.19 KEG14795.1 - 5.9 6.6 17.2 1.3 8.8 9.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family GNAT_acetyltr_2 PF13718.6 KEG14796.1 - 1.8e-85 285.9 0.0 7.1e-85 284.0 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 KEG14796.1 - 5e-59 199.1 0.0 1.4e-58 197.6 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KEG14796.1 - 1.3e-30 105.1 0.1 4.3e-30 103.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 KEG14796.1 - 1.1e-29 103.8 0.0 4.1e-29 101.9 0.0 1.8 1 1 0 1 1 1 1 Possible tRNA binding domain AAA_30 PF13604.6 KEG14796.1 - 0.00028 20.7 1.7 0.06 13.1 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KEG14796.1 - 0.0031 17.8 0.0 0.26 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Pribosyltran_N PF13793.6 KEG14796.1 - 0.028 14.4 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase Oscp1 PF10188.9 KEG14797.1 - 2.7e-53 180.6 0.0 3.9e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 eIF2A PF08662.11 KEG14800.1 - 1e-14 54.9 0.0 3.5e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A FAM60A PF15396.6 KEG14801.1 - 0.035 14.1 0.6 0.056 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A GREB1 PF15782.5 KEG14801.1 - 0.16 9.1 1.4 0.16 9.1 1.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 KEG14801.1 - 0.74 9.4 12.5 1.2 8.7 12.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.8 KEG14801.1 - 2.2 7.9 9.8 3.1 7.3 9.8 1.2 1 0 0 1 1 1 0 Spt20 family Carn_acyltransf PF00755.20 KEG14802.1 - 6.1e-176 586.5 0.0 7.2e-176 586.3 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Macro PF01661.21 KEG14803.1 - 1.6e-34 118.5 0.1 2.4e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 Macro domain Methyltransf_32 PF13679.6 KEG14805.1 - 6.4e-15 55.5 2.4 3.2e-07 30.5 0.2 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 KEG14805.1 - 0.026 15.2 0.6 0.29 11.9 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain SlyX PF04102.12 KEG14806.1 - 0.1 13.2 2.6 0.22 12.2 0.7 2.4 1 1 1 2 2 2 0 SlyX HALZ PF02183.18 KEG14806.1 - 0.12 12.6 0.8 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper MRP-L28 PF09812.9 KEG14806.1 - 0.13 12.3 1.9 0.28 11.3 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 NRBF2 PF08961.10 KEG14806.1 - 0.18 11.4 2.8 11 5.5 0.6 2.5 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Fez1 PF06818.15 KEG14806.1 - 0.31 11.5 7.4 0.11 12.9 1.1 2.1 2 0 0 2 2 2 0 Fez1 SOGA PF11365.8 KEG14806.1 - 0.89 10.7 7.4 4.3 8.5 0.0 3.1 2 2 1 3 3 3 0 Protein SOGA UPF0242 PF06785.11 KEG14806.1 - 0.96 9.5 5.3 1.1 9.4 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4404 PF14357.6 KEG14806.1 - 2 9.1 5.1 0.6 10.8 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ubiquitin PF00240.23 KEG14808.1 - 0.014 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family CTP_transf_like PF01467.26 KEG14810.1 - 6.2e-12 45.9 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Cyt-b5 PF00173.28 KEG14811.1 - 6.1e-17 61.5 0.0 8.3e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ferric_reduct PF01794.19 KEG14811.1 - 0.055 13.6 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase like transmembrane component ALO PF04030.14 KEG14812.1 - 1.7e-70 237.8 5.3 1.4e-67 228.2 1.7 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KEG14812.1 - 6.4e-25 87.5 0.2 1.1e-24 86.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.12 KEG14813.1 - 1.4e-35 123.3 0.3 1.4e-35 123.3 0.3 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KEG14813.1 - 2.6e-14 53.3 0.0 1.1e-13 51.3 0.0 2.2 1 0 0 1 1 1 1 NUC130/3NT domain Sigma70_ner PF04546.13 KEG14813.1 - 8.6 6.2 11.6 1.4 8.8 3.8 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region Syja_N PF02383.18 KEG14814.1 - 4.3e-34 118.3 0.0 1.6e-33 116.4 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain Glutaredoxin PF00462.24 KEG14816.1 - 0.00014 22.0 0.4 0.0016 18.6 0.1 2.1 1 1 1 2 2 2 1 Glutaredoxin YtzH PF14165.6 KEG14817.1 - 0.061 13.7 1.0 0.24 11.8 1.0 2.0 1 0 0 1 1 1 0 YtzH-like protein DUF724 PF05266.14 KEG14817.1 - 0.23 11.3 9.2 1.1 9.0 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF724) ERM PF00769.19 KEG14817.1 - 0.24 11.2 20.3 0.71 9.6 20.3 1.8 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BASP1 PF05466.12 KEG14817.1 - 1.3 9.0 3.1 1.9 8.4 3.1 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Fib_alpha PF08702.10 KEG14817.1 - 2.7 8.2 14.8 2.4 8.3 2.0 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MPS2 PF17060.5 KEG14817.1 - 6 6.0 15.6 0.027 13.7 4.7 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF1168 PF06658.12 KEG14818.1 - 7.5 6.4 16.1 0.34 10.7 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) MPC PF03650.13 KEG14819.1 - 2.9e-14 53.1 0.1 3.6e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Vac14_Fig4_bd PF11916.8 KEG14820.1 - 4.8e-48 163.2 5.7 4.9e-48 163.2 3.7 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KEG14820.1 - 1.1e-05 26.0 0.1 0.00013 22.5 0.1 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Kinesin PF00225.23 KEG14822.1 - 4.8e-67 226.2 0.0 1.2e-66 225.0 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG14822.1 - 7e-13 48.8 0.0 4.7e-12 46.1 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding Tropomyosin_1 PF12718.7 KEG14822.1 - 1.4e-07 31.8 37.3 0.00031 20.9 3.6 5.4 2 2 4 6 6 6 2 Tropomyosin like AAA_22 PF13401.6 KEG14822.1 - 0.042 14.1 0.4 0.27 11.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEG14822.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Med21 PF11221.8 KEG14822.1 - 0.07 13.4 0.3 0.07 13.4 0.3 4.7 3 1 1 6 6 6 0 Subunit 21 of Mediator complex MMR_HSR1 PF01926.23 KEG14822.1 - 0.083 13.0 0.3 0.96 9.6 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase Spc7 PF08317.11 KEG14822.1 - 0.12 11.2 38.6 0.52 9.1 2.6 3.6 1 1 1 3 3 3 0 Spc7 kinetochore protein Takusan PF04822.13 KEG14822.1 - 0.16 11.9 1.3 3.5 7.6 0.1 2.8 2 0 0 2 2 2 0 Takusan AAA_16 PF13191.6 KEG14822.1 - 0.53 10.7 0.0 0.53 10.7 0.0 3.9 3 1 0 3 3 2 0 AAA ATPase domain TMF_TATA_bd PF12325.8 KEG14822.1 - 2.5 8.4 37.1 4.2 7.6 1.6 5.6 3 2 1 5 5 5 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 KEG14822.1 - 4.1 6.7 31.3 0.09 12.1 1.9 4.8 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding Kelch_6 PF13964.6 KEG14823.1 - 2.5e-11 43.4 8.4 0.039 14.2 0.2 6.4 7 2 1 8 8 8 4 Kelch motif Kelch_2 PF07646.15 KEG14823.1 - 2.4e-07 30.5 1.9 3.2 7.9 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KEG14823.1 - 1.2e-05 25.1 2.5 3.1 7.9 0.1 4.6 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KEG14823.1 - 0.00029 21.0 2.9 0.028 14.7 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG14823.1 - 0.00052 19.5 1.2 2.3 7.9 0.0 5.1 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 KEG14823.1 - 0.0016 18.4 10.0 0.37 10.8 0.2 5.6 6 1 0 6 6 6 2 Galactose oxidase, central domain C2 PF00168.30 KEG14825.1 - 0.0032 17.7 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Rubredoxin PF00301.20 KEG14825.1 - 0.0099 15.9 0.3 0.025 14.6 0.3 1.6 1 0 0 1 1 1 1 Rubredoxin OrsD PF12013.8 KEG14825.1 - 0.051 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D WD40 PF00400.32 KEG14826.1 - 4.1e-06 27.4 9.2 0.31 12.0 0.0 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Pkinase PF00069.25 KEG14828.1 - 1.4e-63 214.8 0.0 1.8e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14828.1 - 8.5e-45 153.1 0.0 1.4e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14828.1 - 5.3e-06 26.0 0.0 2.7e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEG14828.1 - 0.0056 15.5 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FSA_C PF10479.9 KEG14828.1 - 9.1 4.3 8.8 13 3.8 8.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4272 PF14094.6 KEG14829.1 - 0.018 14.3 0.0 0.047 12.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4272) EMP24_GP25L PF01105.24 KEG14830.1 - 3.9e-23 82.3 0.1 6e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EF-hand_8 PF13833.6 KEG14831.1 - 0.085 12.7 0.1 0.27 11.1 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair tRNA-synt_1b PF00579.25 KEG14832.1 - 5.7e-59 199.8 0.0 3.2e-52 177.7 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) PX PF00787.24 KEG14833.1 - 2.5e-07 30.7 0.3 4.3e-07 29.9 0.3 1.3 1 0 0 1 1 1 1 PX domain DnaJ PF00226.31 KEG14834.1 - 1.2e-20 73.4 2.9 2.6e-20 72.3 2.9 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 KEG14834.1 - 3.1e-10 40.4 28.3 0.0027 18.2 3.9 5.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14834.1 - 5.2e-08 32.4 0.4 0.012 15.3 0.1 3.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 KEG14834.1 - 4.1e-06 26.5 25.2 0.029 14.5 0.6 7.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14834.1 - 5.7e-06 26.7 27.3 0.0095 16.7 2.7 6.9 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14834.1 - 9.8e-06 25.4 2.8 0.096 12.9 0.0 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG14834.1 - 5.3e-05 23.3 23.0 0.035 14.2 0.5 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEG14834.1 - 0.00042 20.0 12.7 0.35 10.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat JAKMIP_CC3 PF16034.5 KEG14834.1 - 0.035 14.1 0.1 0.035 14.1 0.1 2.9 3 1 0 3 3 2 0 JAKMIP CC3 domain TPR_17 PF13431.6 KEG14834.1 - 0.05 14.0 9.9 0.19 12.1 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG14834.1 - 0.051 13.9 9.4 1.5 9.1 1.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEG14834.1 - 0.077 13.1 2.0 2.3 8.4 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG14834.1 - 0.15 12.7 21.9 0.18 12.5 0.4 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF884 PF05959.11 KEG14834.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) TPR_20 PF14561.6 KEG14834.1 - 0.37 11.1 12.2 2.2 8.6 0.9 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KEG14834.1 - 0.6 10.6 5.9 1.2 9.6 0.1 3.1 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KEG14834.1 - 1.3 9.2 8.9 0.42 10.7 0.1 4.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SHMT PF00464.19 KEG14835.1 - 5.1e-170 565.4 0.0 6.3e-170 565.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KEG14835.1 - 0.054 12.8 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase EMP24_GP25L PF01105.24 KEG14837.1 - 3.9e-44 150.8 0.1 7.3e-44 149.9 0.0 1.4 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD DUF3456 PF11938.8 KEG14839.1 - 2.7e-19 70.2 0.4 4.2e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP Endosulfine PF04667.17 KEG14840.1 - 2.5e-05 24.3 0.1 2.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4200 PF13863.6 KEG14841.1 - 2.8e-21 76.1 15.4 2.8e-21 76.1 15.4 4.9 4 1 0 4 4 4 2 Domain of unknown function (DUF4200) PAPS_reduct PF01507.19 KEG14841.1 - 9.5 6.2 12.8 0.25 11.4 2.4 3.0 2 1 1 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Mucin PF01456.17 KEG14842.1 - 0.011 15.8 8.6 0.012 15.7 8.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 KEG14842.1 - 0.67 9.9 9.5 1 9.3 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 KEG14842.1 - 3 5.7 6.2 3.7 5.4 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 KEG14842.1 - 4.7 5.3 12.0 5.7 5.0 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribo_biogen_C PF04034.13 KEG14843.1 - 8.1e-48 161.3 0.0 1.1e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KEG14843.1 - 3.4e-08 33.2 0.1 6.8e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2722 PF10846.8 KEG14843.1 - 0.84 8.5 7.5 1.1 8.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 KEG14843.1 - 2.6 7.4 19.8 3 7.2 19.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KEG14843.1 - 4.6 5.2 26.4 5.5 5.0 26.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 KEG14843.1 - 5.3 6.9 9.5 9.9 6.1 9.5 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 KEG14843.1 - 7.1 6.4 12.2 10 5.8 12.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 KEG14843.1 - 7.8 4.7 15.0 8.6 4.5 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Vps35 PF03635.17 KEG14845.1 - 5.7e-05 21.8 0.0 0.00017 20.3 0.0 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 35 Bestrophin PF01062.21 KEG14845.1 - 0.081 12.3 0.1 16 4.8 0.0 2.6 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Acyltransferase PF01553.21 KEG14846.1 - 1.2e-18 67.1 0.1 2.5e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase DnaJ_C PF01556.18 KEG14848.1 - 7.4e-31 107.2 0.0 9.8e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG14848.1 - 6.5e-16 58.2 0.1 1e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Sugarporin_N PF11471.8 KEG14850.1 - 3.3 7.7 9.8 9.8 6.2 6.2 2.9 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension SlyX PF04102.12 KEG14850.1 - 5.2 7.8 19.4 0.026 15.1 6.1 4.1 3 1 0 3 3 3 0 SlyX DUF647 PF04884.14 KEG14852.1 - 2e-41 142.2 5.8 2.9e-41 141.7 5.8 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TctB PF07331.11 KEG14854.1 - 0.042 14.1 0.2 0.074 13.3 0.2 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family SpoIID PF08486.10 KEG14854.1 - 0.18 12.4 3.5 1.5 9.4 1.5 2.7 2 1 0 2 2 2 0 Stage II sporulation protein Tmemb_14 PF03647.13 KEG14855.1 - 4e-17 62.7 10.0 4.7e-17 62.5 10.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C FUSC_2 PF13515.6 KEG14855.1 - 0.0022 18.1 3.7 0.0028 17.8 3.7 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2232 PF09991.9 KEG14855.1 - 0.19 10.9 6.2 0.35 10.0 6.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) LptF_LptG PF03739.14 KEG14855.1 - 0.19 10.5 3.7 0.08 11.8 0.8 1.7 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG CBFD_NFYB_HMF PF00808.23 KEG14857.1 - 0.0011 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEG14857.1 - 0.12 12.8 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Cation_efflux PF01545.21 KEG14858.1 - 0.092 12.5 4.6 0.24 11.1 4.6 1.8 1 1 0 1 1 1 0 Cation efflux family Cpn60_TCP1 PF00118.24 KEG14861.1 - 1.5e-81 274.5 6.9 3e-81 273.5 6.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.22 KEG14862.1 - 4.5e-37 127.1 0.0 5.5e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG14862.1 - 1.5e-32 112.3 0.0 2.2e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG14862.1 - 5.3e-10 39.0 0.0 6.5e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG14862.1 - 3.9e-06 26.4 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEG14862.1 - 2.8e-05 23.7 0.0 5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEG14862.1 - 2.8e-05 24.2 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEG14862.1 - 6.8e-05 22.5 0.0 0.0024 17.5 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KEG14862.1 - 0.0003 20.3 0.0 0.007 15.8 0.0 2.6 3 0 0 3 3 3 1 Bacterial TniB protein RsgA_GTPase PF03193.16 KEG14862.1 - 0.002 18.1 0.0 2.4 8.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KEG14862.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 KEG14862.1 - 0.012 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 KEG14862.1 - 0.052 13.9 0.0 0.076 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Sod_Fe_C PF02777.18 KEG14863.1 - 2.6e-39 133.5 2.3 3.5e-39 133.1 0.7 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEG14863.1 - 2e-22 79.5 0.9 5.9e-22 77.9 0.1 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GH101_N PF17995.1 KEG14863.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Endo-alpha-N-acetylgalactosaminidase N-terminal Pkinase PF00069.25 KEG14864.1 - 9.1e-55 185.8 0.0 1.7e-53 181.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14864.1 - 6.6e-30 104.3 0.0 2.7e-29 102.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KEG14864.1 - 2.2e-08 34.5 0.0 4.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KEG14864.1 - 0.001 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3408 PF11888.8 KEG14864.1 - 0.0057 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) Kinase-like PF14531.6 KEG14864.1 - 0.0095 15.3 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 KEG14864.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain GSH_synthase PF03199.15 KEG14865.1 - 0.0012 19.2 0.0 0.0015 19.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic glutathione synthase SMN PF06003.12 KEG14865.1 - 0.0044 16.3 4.0 0.036 13.3 0.1 2.3 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) GRAM PF02893.20 KEG14866.1 - 1.4e-15 57.1 0.0 3.5e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 GRAM domain SPA PF08616.10 KEG14867.1 - 1.8e-28 98.8 0.0 3.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KEG14867.1 - 0.00017 22.1 0.0 0.00042 20.8 0.0 1.7 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KEG14867.1 - 0.00064 18.5 0.0 0.021 13.5 0.0 2.2 1 1 1 2 2 2 1 Transport protein Avl9 DUF2347 PF09804.9 KEG14867.1 - 0.0086 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) TPR_1 PF00515.28 KEG14869.1 - 1.5e-23 81.6 2.7 1e-06 28.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEG14869.1 - 2.2e-16 58.6 8.2 4.4e-05 23.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14869.1 - 6.4e-12 44.7 2.8 0.011 15.9 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEG14869.1 - 8.4e-12 44.6 4.1 0.0017 18.0 0.0 3.7 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 KEG14869.1 - 1.1e-07 32.4 0.1 6.3e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG14869.1 - 2.3e-07 30.7 1.0 0.023 15.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.11 KEG14869.1 - 1.4e-06 27.1 0.9 3.1e-06 25.9 0.9 1.5 1 0 0 1 1 1 1 SGT1 protein TPR_12 PF13424.6 KEG14869.1 - 2.3e-06 27.8 0.7 0.001 19.3 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG14869.1 - 7e-06 26.4 0.3 0.38 11.7 0.0 4.0 2 1 2 4 4 3 2 Tetratricopeptide repeat STI1 PF17830.1 KEG14869.1 - 1.2e-05 25.1 16.6 8e-05 22.5 0.6 4.2 5 1 0 5 5 4 2 STI1 domain TPR_7 PF13176.6 KEG14869.1 - 7.6e-05 22.5 1.7 0.62 10.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14869.1 - 0.00018 21.9 0.7 0.49 10.9 0.0 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEG14869.1 - 0.00071 19.6 4.1 0.68 10.0 0.1 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KEG14869.1 - 0.0009 19.3 0.0 0.0036 17.4 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 KEG14869.1 - 0.013 15.3 1.0 0.26 11.0 0.0 2.9 1 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 KEG14869.1 - 0.023 14.7 0.4 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ins_allergen_rp PF06757.13 KEG14869.1 - 0.027 14.5 1.0 1.4 8.8 0.0 2.7 3 0 0 3 3 2 0 Insect allergen related repeat, nitrile-specifier detoxification MIT PF04212.18 KEG14869.1 - 0.057 13.5 7.3 2 8.5 0.2 3.3 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Integrin_b_cyt PF08725.11 KEG14869.1 - 0.078 12.7 1.2 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain ANAPC3 PF12895.7 KEG14869.1 - 0.15 12.3 2.0 0.57 10.4 1.7 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KEG14869.1 - 0.24 11.3 1.9 2.3 8.2 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GerD PF17898.1 KEG14869.1 - 0.98 9.4 6.6 1.9 8.5 1.1 3.2 3 0 0 3 3 3 0 Spore germination GerD central core domain Sod_Fe_C PF02777.18 KEG14872.1 - 8.5e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEG14872.1 - 0.00015 22.2 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-CCCH PF00642.24 KEG14874.1 - 1.6e-06 27.8 4.4 2.8e-06 27.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG14874.1 - 0.00056 19.9 4.7 0.0015 18.5 4.7 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEG14874.1 - 0.0023 17.7 2.1 0.0042 16.9 2.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger DUF872 PF05915.12 KEG14875.1 - 1.3e-11 44.6 0.1 1.4e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Claudin_2 PF13903.6 KEG14875.1 - 0.0086 15.8 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SPC12 PF06645.13 KEG14875.1 - 0.1 12.7 2.1 0.24 11.5 2.1 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3592 PF12158.8 KEG14875.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF3040 PF11239.8 KEG14875.1 - 1 9.7 7.5 0.45 10.8 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Myb_DNA-bind_7 PF15963.5 KEG14876.1 - 0.0061 16.4 0.7 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Myb DNA-binding like BacA PF02673.18 KEG14876.1 - 0.05 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA Cpn60_TCP1 PF00118.24 KEG14878.1 - 1e-69 235.5 5.8 4.1e-69 233.5 5.8 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family 2CSK_N PF08521.10 KEG14878.1 - 0.23 11.5 1.4 4 7.5 0.1 2.4 1 1 1 2 2 2 0 Two-component sensor kinase N-terminal DUF1839 PF08893.10 KEG14878.1 - 0.24 10.5 0.3 0.39 9.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) RabGAP-TBC PF00566.18 KEG14880.1 - 7.3e-37 127.1 0.0 1.4e-36 126.2 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain R3H PF01424.22 KEG14880.1 - 0.036 14.1 0.0 0.4 10.7 0.0 2.6 3 0 0 3 3 3 0 R3H domain DDT PF02791.17 KEG14880.1 - 0.09 13.1 2.2 0.43 10.9 0.2 2.7 2 0 0 2 2 2 0 DDT domain Myosin_head PF00063.21 KEG14883.1 - 1.5e-09 36.7 0.2 1.5e-09 36.7 0.2 2.2 3 0 0 3 3 3 1 Myosin head (motor domain) FUN14 PF04930.15 KEG14884.1 - 0.004 17.5 0.3 0.0061 16.9 0.3 1.3 1 0 0 1 1 1 1 FUN14 family Bunya_NS-S PF01104.17 KEG14887.1 - 0.0068 16.2 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Bunyavirus non-structural protein NS-s DUF1319 PF07028.11 KEG14887.1 - 0.031 14.5 1.2 0.038 14.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) ApoO PF09769.9 KEG14887.1 - 0.048 13.6 0.2 0.07 13.1 0.2 1.3 1 1 0 1 1 1 0 Apolipoprotein O FapA PF03961.13 KEG14887.1 - 0.14 10.8 3.1 0.14 10.7 3.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FUN14 PF04930.15 KEG14889.1 - 2e-20 73.0 1.6 2.6e-20 72.6 1.6 1.1 1 0 0 1 1 1 1 FUN14 family EF-hand_6 PF13405.6 KEG14889.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KEG14889.1 - 0.026 14.1 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KEG14889.1 - 0.16 11.5 0.3 0.28 10.7 0.3 1.3 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KEG14889.1 - 0.17 12.4 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair PPR_2 PF13041.6 KEG14890.1 - 1.1e-06 28.7 0.0 0.92 9.8 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family TPR_14 PF13428.6 KEG14890.1 - 9e-06 26.1 9.6 35 5.6 0.5 7.1 4 2 3 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 KEG14890.1 - 0.001 19.2 8.0 0.54 10.6 0.0 6.1 7 0 0 7 7 7 1 PPR repeat P3A PF08727.11 KEG14890.1 - 0.031 13.7 0.0 0.089 12.2 0.0 1.7 1 0 0 1 1 1 0 Poliovirus 3A protein like TPR_16 PF13432.6 KEG14890.1 - 0.041 14.5 9.3 8 7.2 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG14890.1 - 0.041 14.4 9.3 2 9.0 0.2 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Raf1_HTH PF18579.1 KEG14890.1 - 0.043 13.5 0.1 2.2 8.0 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ANAPC3 PF12895.7 KEG14890.1 - 0.11 12.7 0.2 4 7.7 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Aldedh PF00171.22 KEG14892.1 - 1.2e-121 406.5 0.0 1.6e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEG14892.1 - 5.5e-06 26.0 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Pkinase PF00069.25 KEG14893.1 - 5.4e-47 160.4 0.0 8e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14893.1 - 4.7e-13 49.0 0.0 6.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG14893.1 - 1.3e-05 25.2 0.4 1.8e-05 24.8 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG14893.1 - 2.3e-05 23.9 0.1 7.7e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG14893.1 - 0.16 10.7 0.1 0.23 10.2 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Taxilin PF09728.9 KEG14894.1 - 0.00057 19.2 10.3 0.00057 19.2 10.3 2.1 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF4515 PF14988.6 KEG14894.1 - 0.0057 16.5 20.5 0.3 10.9 8.1 2.8 1 1 0 2 2 2 2 Domain of unknown function (DUF4515) Spc29 PF17082.5 KEG14894.1 - 0.032 14.1 1.8 0.048 13.5 1.8 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4055 PF13264.6 KEG14894.1 - 0.1 12.7 2.0 0.37 11.0 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) DUF16 PF01519.16 KEG14894.1 - 0.17 12.4 10.4 0.083 13.4 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 LMP PF04778.12 KEG14894.1 - 0.2 11.6 3.1 0.39 10.6 3.1 1.4 1 0 0 1 1 1 0 LMP repeated region Spc7 PF08317.11 KEG14894.1 - 0.95 8.3 16.6 1.9 7.3 16.6 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 KEG14894.1 - 1.5 9.2 11.6 0.45 10.9 0.9 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 KEG14894.1 - 4.8 6.5 24.5 2.6 7.4 6.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 LMBR1 PF04791.16 KEG14894.1 - 6.6 5.5 7.4 8.9 5.1 7.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAS PF13851.6 KEG14894.1 - 7 5.9 22.8 6.4 6.1 18.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KEG14894.1 - 7.6 5.9 20.2 7.4 5.9 2.8 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PI-PLC-X PF00388.19 KEG14898.1 - 9.8e-59 197.1 0.0 1.9e-58 196.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEG14898.1 - 2.4e-33 114.9 0.0 4.8e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_6 PF13405.6 KEG14898.1 - 4.9e-11 41.6 0.3 0.00012 21.7 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KEG14898.1 - 3e-10 38.9 0.8 0.00081 18.8 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KEG14898.1 - 3.2e-10 40.3 0.7 5.7e-09 36.3 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 KEG14898.1 - 4.4e-07 29.6 0.8 9.5e-07 28.6 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KEG14898.1 - 4.6e-07 29.0 0.7 0.00048 19.5 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KEG14898.1 - 8.6e-07 28.7 0.1 0.0052 16.6 0.1 3.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KEG14898.1 - 0.0016 18.8 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C2 PF00168.30 KEG14898.1 - 0.0084 16.4 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_4 PF12763.7 KEG14898.1 - 0.02 14.8 0.1 0.16 12.0 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-CHCC PF10276.9 KEG14899.1 - 0.0026 17.8 2.7 0.0026 17.8 2.7 2.0 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_N PF00044.24 KEG14900.1 - 1.9e-31 108.4 0.1 3.7e-31 107.5 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KEG14900.1 - 1e-28 99.9 0.2 2.1e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KEG14900.1 - 0.1 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEG14900.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain RRM_1 PF00076.22 KEG14901.1 - 2.7e-19 68.7 0.1 5.4e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEG14901.1 - 9.4e-05 22.5 0.0 0.048 13.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif TAFH PF07531.14 KEG14902.1 - 0.16 12.1 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 NHR1 homology to TAF RNA_pol_Rpb4 PF03874.16 KEG14903.1 - 0.0026 18.1 0.0 0.0062 16.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF465 PF04325.13 KEG14903.1 - 0.018 15.1 0.9 0.04 14.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Macoilin PF09726.9 KEG14905.1 - 0.82 8.1 11.9 1.4 7.4 11.9 1.3 1 0 0 1 1 1 0 Macoilin family DUF3245 PF11595.8 KEG14905.1 - 0.95 9.9 5.4 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) SWIRM-assoc_2 PF16496.5 KEG14905.1 - 3.4 6.4 9.5 5.6 5.7 9.5 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PPR PF01535.20 KEG14906.1 - 0.00093 19.3 0.0 1.9 8.9 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 KEG14906.1 - 0.0055 16.9 0.0 2.6 8.3 0.0 3.2 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 KEG14906.1 - 0.024 14.7 0.0 0.39 10.8 0.0 2.9 2 1 0 2 2 2 0 Pentatricopeptide repeat domain Metallophos PF00149.28 KEG14907.1 - 2.4e-07 31.5 0.1 3.6e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4834 PF16118.5 KEG14908.1 - 0.09 13.7 0.0 0.14 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 KEG14908.1 - 1.3 9.3 6.4 0.57 10.4 0.2 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Rad51 PF08423.11 KEG14909.1 - 1e-13 51.2 2.9 2e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 Rad51 ATPase PF06745.13 KEG14909.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 KEG14909.1 - 0.0015 18.2 0.2 0.0045 16.6 0.2 1.8 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KEG14909.1 - 0.016 14.7 0.2 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 recA bacterial DNA recombination protein PhoH PF02562.16 KEG14909.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mgm101p PF06420.12 KEG14909.1 - 0.21 11.1 0.0 0.48 9.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 MitMem_reg PF13012.6 KEG14910.1 - 0.012 16.0 1.2 0.012 16.0 1.2 2.7 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function zf-C4H2 PF10146.9 KEG14910.1 - 0.42 10.9 15.1 0.052 13.8 0.7 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein Sec34 PF04136.15 KEG14910.1 - 0.47 10.3 8.3 0.21 11.5 0.7 3.1 3 2 0 3 3 3 0 Sec34-like family Tup_N PF08581.10 KEG14910.1 - 3.3 8.1 19.6 0.18 12.1 0.7 4.5 4 1 0 4 4 4 0 Tup N-terminal FlaC_arch PF05377.11 KEG14910.1 - 5.8 7.4 9.9 42 4.6 0.2 4.4 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) GAS PF13851.6 KEG14910.1 - 7.2 5.9 32.7 0.36 10.1 0.5 4.2 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding MccV PF17508.2 KEG14911.1 - 0.095 13.3 0.4 0.095 13.3 0.4 1.8 2 0 0 2 2 2 0 Microcin V bacteriocin CMD PF02627.20 KEG14911.1 - 0.16 12.1 2.7 0.16 12.0 0.4 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Peptidase_M60 PF13402.6 KEG14912.1 - 4.2 6.8 6.2 12 5.3 0.4 2.2 1 1 1 2 2 2 0 Peptidase M60, enhancin and enhancin-like TPR_17 PF13431.6 KEG14914.1 - 0.0094 16.3 2.5 3.8 8.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEG14914.1 - 0.013 15.7 15.0 0.44 10.7 0.5 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat F-box-like PF12937.7 KEG14914.1 - 0.058 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like TPR_14 PF13428.6 KEG14914.1 - 2.1 9.4 9.8 20 6.3 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Cofilin_ADF PF00241.20 KEG14915.1 - 7.4e-30 103.2 0.0 8.5e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UPF0552 PF10574.9 KEG14915.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Arp2/3-interacting proteins Arpin Mito_fiss_reg PF05308.11 KEG14916.1 - 0.1 12.7 4.5 5.5 7.0 1.7 2.7 3 0 0 3 3 3 0 Mitochondrial fission regulator CAP_N PF01213.19 KEG14916.1 - 0.19 11.2 12.3 0.55 9.7 6.2 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MerR PF00376.23 KEG14917.1 - 0.12 12.2 0.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 MerR family regulatory protein RNase_T PF00929.24 KEG14918.1 - 2e-27 96.7 0.0 6.5e-27 95.1 0.0 1.8 1 1 0 1 1 1 1 Exonuclease Phage_int_SAM_2 PF12834.7 KEG14918.1 - 0.17 12.6 1.2 0.28 11.9 0.2 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal RNase_T PF00929.24 KEG14919.1 - 2e-24 87.0 0.0 3.3e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KEG14919.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like RNase_T PF00929.24 KEG14920.1 - 4.8e-25 89.0 0.0 9e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF3453 PF11935.8 KEG14920.1 - 1.8 8.2 3.7 2.5 7.7 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Zip PF02535.22 KEG14920.1 - 7.6 5.6 5.0 15 4.7 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ank_4 PF13637.6 KEG14921.1 - 1.8e-11 44.3 0.2 2.1e-05 25.0 0.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG14921.1 - 9.9e-10 38.9 0.0 4.7e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEG14921.1 - 1.9e-09 37.0 1.9 0.015 15.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KEG14921.1 - 4.5e-07 30.0 0.6 0.43 11.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KEG14921.1 - 0.1 12.9 3.5 0.21 11.9 0.3 3.1 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Mre11_DNA_bind PF04152.14 KEG14922.1 - 0.73 10.1 5.6 0.14 12.4 0.5 2.0 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain ERCC3_RAD25_C PF16203.5 KEG14923.1 - 1.2e-69 234.3 0.1 1.4e-66 224.2 0.0 2.3 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEG14923.1 - 7.2e-15 55.4 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_3 PF13625.6 KEG14923.1 - 1.2e-09 38.3 0.0 4.9e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 KEG14923.1 - 2.7e-09 37.4 0.0 7.5e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEG14923.1 - 7.9e-05 21.5 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PABP PF00658.18 KEG14924.1 - 4.8e-20 71.5 0.1 5.2e-20 71.4 0.1 1.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain bVLRF1 PF18826.1 KEG14926.1 - 5.1e-39 133.5 0.3 1.3e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor acVLRF1 PF18859.1 KEG14926.1 - 0.032 14.5 0.4 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Draxin PF15550.6 KEG14926.1 - 0.055 13.3 3.9 0.11 12.3 3.9 1.5 1 0 0 1 1 1 0 Draxin RRN3 PF05327.11 KEG14926.1 - 0.21 10.1 4.5 0.4 9.2 4.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CCDC53 PF10152.9 KEG14926.1 - 0.36 11.2 6.5 0.84 10.0 6.5 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GAGA_bind PF06217.12 KEG14926.1 - 0.52 10.6 8.4 0.83 9.9 8.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2052 PF09747.9 KEG14926.1 - 0.93 9.6 15.4 2.9 8.0 12.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Spore_III_AF PF09581.10 KEG14926.1 - 1.3 9.1 11.8 0.94 9.5 9.2 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) PRP38_assoc PF12871.7 KEG14926.1 - 1.6 9.4 14.9 0.43 11.2 9.1 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term YL1 PF05764.13 KEG14926.1 - 1.7 8.7 17.7 0.15 12.2 11.3 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Presenilin PF01080.17 KEG14926.1 - 1.9 7.2 4.8 3.2 6.4 4.8 1.3 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 KEG14926.1 - 5 7.8 8.6 2.8 8.6 3.3 2.8 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PX PF00787.24 KEG14927.1 - 1.8e-05 24.7 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PX domain TF_Zn_Ribbon PF08271.12 KEG14928.1 - 0.0046 16.4 0.5 0.011 15.2 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Trm112p PF03966.16 KEG14928.1 - 0.039 14.5 0.2 0.076 13.6 0.2 1.5 1 0 0 1 1 1 0 Trm112p-like protein Inhibitor_I9 PF05922.16 KEG14929.1 - 0.0043 17.7 1.1 0.0092 16.6 0.1 2.0 1 1 1 2 2 2 1 Peptidase inhibitor I9 PRORP PF16953.5 KEG14930.1 - 5.4e-31 108.0 0.0 6.2e-24 84.9 0.1 2.2 2 0 0 2 2 2 2 Protein-only RNase P RNase_Zc3h12a PF11977.8 KEG14930.1 - 0.071 12.9 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.19 KEG14931.1 - 1.9e-24 85.6 7.2 3.2e-24 84.8 7.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zf-P11 PF03854.14 KEG14931.1 - 0.0049 16.5 0.6 0.0083 15.8 0.6 1.4 1 0 0 1 1 1 1 P-11 zinc finger ALG11_N PF15924.5 KEG14932.1 - 2.1e-57 194.6 0.0 3.1e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KEG14932.1 - 1.8e-23 83.0 0.0 3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEG14932.1 - 4.2e-13 49.9 0.0 7.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 KEG14935.1 - 7.8e-43 146.7 0.0 1.3e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14935.1 - 1.1e-16 60.9 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14935.1 - 5.5e-08 32.5 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG14935.1 - 0.0009 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase MMR_HSR1 PF01926.23 KEG14936.1 - 0.00066 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG14936.1 - 0.037 13.9 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KEG14936.1 - 0.044 14.2 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KEG14936.1 - 0.14 11.7 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KEG14936.1 - 0.24 11.6 0.0 0.42 10.8 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_C92 PF05708.12 KEG14937.1 - 0.0047 17.1 0.0 0.046 13.8 0.0 2.2 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family zf-CCCH PF00642.24 KEG14938.1 - 0.0024 17.8 0.3 0.0024 17.8 0.3 2.5 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEG14938.1 - 0.01 15.9 0.1 0.01 15.9 0.1 2.6 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KEG14938.1 - 0.038 14.2 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 KEG14938.1 - 0.63 10.8 5.6 0.96 10.2 0.2 2.2 1 1 1 2 2 2 0 Torus domain MMR_HSR1 PF01926.23 KEG14939.1 - 5.8e-11 42.5 0.0 3.1e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG14939.1 - 3.9e-06 26.9 0.0 2.2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KEG14939.1 - 0.0066 16.7 0.0 0.02 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 KEG14939.1 - 0.0071 15.9 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEG14939.1 - 0.056 13.5 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KEG14939.1 - 0.091 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KEG14939.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KEG14939.1 - 0.17 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DivIVA PF05103.13 KEG14940.1 - 0.027 14.6 0.4 0.027 14.6 0.4 4.1 4 2 1 5 5 5 0 DivIVA protein V-ATPase_H_C PF11698.8 KEG14940.1 - 0.067 13.3 1.1 0.18 11.9 0.6 2.0 2 0 0 2 2 2 0 V-ATPase subunit H DUF1479 PF07350.12 KEG14940.1 - 0.11 11.2 0.6 1.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Shugoshin_N PF07558.11 KEG14940.1 - 0.58 10.1 7.1 3.5 7.6 0.3 3.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF2935 PF11155.8 KEG14940.1 - 2.2 8.6 5.8 13 6.1 0.2 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF2935) Nsp1_C PF05064.13 KEG14940.1 - 4 7.3 13.5 1.5 8.6 0.6 3.1 3 1 1 4 4 4 0 Nsp1-like C-terminal region Methyltransf_4 PF02390.17 KEG14941.1 - 5.2e-35 120.5 0.0 6.7e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 KEG14941.1 - 3.2e-05 23.8 0.0 6.7e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG14941.1 - 0.00032 21.4 0.0 0.0006 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG14941.1 - 0.0011 19.6 0.0 0.0023 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KEG14941.1 - 0.032 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KEG14941.1 - 0.19 11.2 0.0 0.56 9.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain ABC2_membrane_6 PF06182.11 KEG14942.1 - 0.02 14.7 0.9 0.023 14.5 0.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein HALZ PF02183.18 KEG14943.1 - 8.3e-06 25.9 1.3 1.5e-05 25.1 1.3 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Fungal_TACC PF12709.7 KEG14943.1 - 0.0011 19.3 0.4 0.0017 18.8 0.2 1.5 1 1 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1640 PF07798.11 KEG14943.1 - 0.0014 18.7 0.3 0.0016 18.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DivIC PF04977.15 KEG14943.1 - 0.0028 17.4 3.4 0.0068 16.2 1.0 2.0 2 0 0 2 2 2 1 Septum formation initiator DivIVA PF05103.13 KEG14943.1 - 0.012 15.7 0.9 0.012 15.7 0.9 1.7 1 1 1 2 2 2 0 DivIVA protein Cnn_1N PF07989.11 KEG14943.1 - 0.026 14.7 1.7 0.034 14.3 0.1 1.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KEG14943.1 - 0.067 13.6 2.2 0.067 13.6 2.2 2.0 2 1 0 2 2 2 0 Cell division protein ZapB Dpy-30 PF05186.13 KEG14943.1 - 0.075 12.7 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Dpy-30 motif Seadorna_VP6 PF07407.11 KEG14943.1 - 0.09 11.7 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF5320 PF17253.2 KEG14943.1 - 0.14 13.2 1.3 0.14 13.2 1.3 1.5 1 1 0 2 2 2 0 Family of unknown function (DUF5320) Antimicrobial20 PF08256.11 KEG14943.1 - 0.16 12.5 1.0 0.39 11.4 1.0 1.7 1 0 0 1 1 1 0 Aurein-like antibiotic peptide WD40 PF00400.32 KEG14944.1 - 6.2e-13 49.0 10.0 0.001 19.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2722 PF10846.8 KEG14944.1 - 0.043 12.8 1.6 0.053 12.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 KEG14944.1 - 9 5.0 6.5 12 4.6 6.5 1.1 1 0 0 1 1 1 0 Androgen receptor MMR_HSR1_Xtn PF16897.5 KEG14948.1 - 1.8e-38 130.8 1.5 3.2e-38 130.0 1.5 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KEG14948.1 - 1.3e-23 82.8 0.1 2.7e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KEG14948.1 - 2.5e-18 66.2 0.0 5.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEG14948.1 - 2.4e-09 36.9 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEG14948.1 - 0.0034 17.4 0.3 0.39 10.8 0.0 2.6 1 1 0 2 2 2 1 Dynamin family AIG1 PF04548.16 KEG14948.1 - 0.044 13.1 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family YchF-GTPase_C PF06071.13 KEG14948.1 - 0.062 13.5 0.2 0.36 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF933) MICSWaP PF17018.5 KEG14948.1 - 0.077 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Spore wall protein CRF PF00473.17 KEG14948.1 - 7.1 6.8 5.3 4.4 7.5 1.2 2.9 3 1 0 3 3 3 0 Corticotropin-releasing factor family SAC3_GANP PF03399.16 KEG14949.1 - 2e-10 40.5 2.1 5.8e-09 35.8 2.1 2.4 1 1 0 1 1 1 1 SAC3/GANP family FMN_dh PF01070.18 KEG14950.1 - 1.1e-28 100.3 0.0 6.2e-21 74.8 0.1 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KEG14950.1 - 5.8e-07 28.8 0.1 0.00011 21.3 0.0 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEG14950.1 - 0.00034 19.9 1.6 0.0013 17.9 1.6 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KEG14950.1 - 0.099 12.1 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 KEG14950.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Ank_2 PF12796.7 KEG14951.1 - 3.9e-06 27.4 0.0 9.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEG14951.1 - 0.00011 22.7 0.0 0.082 13.5 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KEG14951.1 - 0.00013 22.2 0.0 0.046 14.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KEG14951.1 - 0.001 19.4 0.0 7.1 7.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Dynein_heavy PF03028.15 KEG14951.1 - 0.0049 16.9 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Aa_trans PF01490.18 KEG14952.1 - 3.1e-48 164.5 24.8 3.5e-48 164.3 24.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_M48_N PF16491.5 KEG14953.1 - 4.1e-44 150.7 1.1 6.8e-44 149.9 1.1 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KEG14953.1 - 6.9e-38 130.4 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Erf4 PF10256.9 KEG14953.1 - 0.066 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family LRR_4 PF12799.7 KEG14957.1 - 1.5e-21 76.1 12.6 0.0057 17.0 0.1 10.7 6 4 5 12 12 12 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG14957.1 - 2.6e-08 33.5 14.4 0.77 9.6 0.1 8.3 4 3 4 9 9 9 6 Leucine rich repeat LRR_6 PF13516.6 KEG14957.1 - 3.7e-07 29.7 21.0 0.75 10.0 0.0 9.9 10 0 0 10 10 10 3 Leucine Rich repeat LRR_5 PF13306.6 KEG14957.1 - 0.0026 17.7 1.5 15 5.6 0.2 4.6 4 2 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) SAM_Ste50p PF09235.10 KEG14957.1 - 0.93 9.8 5.8 30 4.9 0.0 4.5 4 1 0 4 4 4 0 Ste50p, sterile alpha motif Pkinase PF00069.25 KEG14958.1 - 3.7e-58 197.0 0.0 4.8e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14958.1 - 7.4e-31 107.4 0.0 1.1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEG14958.1 - 0.0057 16.0 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEG14958.1 - 0.0081 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEG14958.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KEG14958.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KEG14958.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TMEM171 PF15471.6 KEG14958.1 - 1.6 7.6 7.6 0.5 9.3 2.4 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 CitF PF04223.12 KEG14959.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Arm PF00514.23 KEG14960.1 - 1.4e-48 161.5 30.3 1.9e-09 37.2 0.1 16.7 17 0 0 17 17 17 9 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KEG14960.1 - 7.2e-05 22.7 2.2 26 4.9 0.0 6.7 7 0 0 7 7 7 0 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 KEG14960.1 - 0.00022 20.8 0.0 0.46 9.9 0.0 4.2 3 1 1 4 4 4 2 Armadillo-like DUF383 PF04063.14 KEG14960.1 - 0.0037 16.9 0.0 13 5.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF383) HEAT_2 PF13646.6 KEG14960.1 - 0.0069 16.7 16.6 0.49 10.8 0.0 6.8 4 4 3 7 7 7 3 HEAT repeats E3_UbLigase_R4 PF13764.6 KEG14960.1 - 0.027 12.7 0.1 0.87 7.7 0.0 2.5 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 HEAT PF02985.22 KEG14960.1 - 0.056 13.7 17.0 0.075 13.3 0.0 6.7 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 KEG14960.1 - 0.27 11.8 25.6 0.35 11.4 0.0 6.1 7 0 0 7 7 7 0 HEAT-like repeat Dicty_REP PF05086.12 KEG14960.1 - 4 5.3 6.8 5.8 4.8 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Utp14 PF04615.13 KEG14961.1 - 1.6e-98 331.2 59.3 1.6e-98 331.2 59.3 2.0 1 1 1 2 2 2 1 Utp14 protein DUF563 PF04577.14 KEG14964.1 - 0.0027 17.9 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF563) LRR_9 PF14580.6 KEG14965.1 - 3.5e-24 85.2 2.3 4.1e-14 52.4 1.1 2.1 2 0 0 2 2 2 2 Leucine-rich repeat DUF4407 PF14362.6 KEG14965.1 - 0.023 14.0 1.7 0.032 13.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_8 PF13855.6 KEG14965.1 - 0.34 10.7 8.0 4.5 7.1 0.5 3.2 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 KEG14965.1 - 0.86 10.4 3.9 1.1e+02 3.9 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich Repeat DUF1936 PF09151.10 KEG14966.1 - 0.005 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1936) HSP70 PF00012.20 KEG14967.1 - 4.6e-08 31.7 0.0 7.4e-08 31.0 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein Rtt106 PF08512.12 KEG14969.1 - 4.3e-10 39.9 0.0 3.2e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KEG14969.1 - 0.0049 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) SDA1 PF05285.12 KEG14969.1 - 0.021 14.3 37.0 0.033 13.6 37.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEG14969.1 - 0.069 11.4 33.3 0.092 11.0 33.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KEG14969.1 - 0.087 11.1 32.4 0.12 10.7 32.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 KEG14969.1 - 0.4 10.0 29.2 0.62 9.4 29.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YL1 PF05764.13 KEG14969.1 - 4.1 7.5 40.5 6.6 6.8 40.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 KEG14969.1 - 6 5.6 16.0 9.6 4.9 16.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sigma70_ner PF04546.13 KEG14969.1 - 7.2 6.4 23.2 17 5.2 23.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region BAF250_C PF12031.8 KEG14970.1 - 0.035 13.4 0.4 0.068 12.5 0.4 1.3 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa SecG PF03840.14 KEG14970.1 - 0.055 13.6 0.1 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 Preprotein translocase SecG subunit WASH-7_C PF14746.6 KEG14970.1 - 0.24 11.1 1.3 11 5.7 1.4 2.6 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal LRR_4 PF12799.7 KEG14971.1 - 5.8e-08 32.9 0.0 0.002 18.5 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG14971.1 - 4e-07 29.7 0.8 0.0082 15.9 0.5 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KEG14971.1 - 0.00076 19.3 3.9 0.84 9.8 0.3 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KEG14971.1 - 0.025 15.1 5.0 39 5.3 0.0 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat AAA_23 PF13476.6 KEG14971.1 - 9.7 6.6 15.6 0.71 10.3 6.8 2.7 3 0 0 3 3 3 0 AAA domain Mito_fiss_reg PF05308.11 KEG14971.1 - 9.7 6.2 19.8 0.11 12.6 6.8 2.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 KEG14973.1 - 1.5e-70 237.6 0.0 2.6e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14973.1 - 3.2e-52 177.4 0.0 5.1e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG14973.1 - 1.2e-06 28.1 0.0 3.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEG14973.1 - 0.0031 17.1 0.3 0.01 15.5 0.3 1.8 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KEG14973.1 - 1.8 7.3 3.9 0.93 8.2 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase WD40 PF00400.32 KEG14974.1 - 2.2e-09 37.8 12.2 2.4e-06 28.1 0.8 7.0 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG14974.1 - 1.8e-07 31.3 0.0 0.94 9.8 0.0 5.3 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nic96 PF04097.14 KEG14974.1 - 0.00057 18.5 0.0 0.022 13.2 0.0 2.2 1 1 0 2 2 2 1 Nup93/Nic96 Coatomer_WDAD PF04053.14 KEG14974.1 - 0.00071 18.7 0.1 2.7 6.9 0.0 4.5 4 2 1 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.6 KEG14974.1 - 0.0018 18.2 3.9 1 9.5 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG14974.1 - 0.0092 16.1 2.4 14 6.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KEG14974.1 - 0.05 13.5 2.1 2.9 7.8 0.0 3.6 3 1 1 4 4 4 0 Region in Clathrin and VPS DZR PF12773.7 KEG14974.1 - 0.45 10.6 6.0 0.2 11.7 0.3 2.8 2 0 0 2 2 2 0 Double zinc ribbon MIT PF04212.18 KEG14974.1 - 0.46 10.6 1.8 15 5.8 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KEG14974.1 - 0.57 10.5 4.5 11 6.4 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 KEG14974.1 - 0.9 8.9 4.6 0.81 9.0 1.1 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP zinc_ribbon_9 PF14369.6 KEG14974.1 - 0.93 9.8 5.7 0.97 9.7 2.6 2.5 2 0 0 2 2 2 0 zinc-ribbon TPR_2 PF07719.17 KEG14974.1 - 3.2 8.1 19.2 0.27 11.5 0.2 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-CCHC_3 PF13917.6 KEG14974.1 - 5.1 7.1 5.8 42 4.2 3.5 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF4207 PF13904.6 KEG14976.1 - 0.002 17.9 4.4 0.002 17.9 4.4 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) GAS PF13851.6 KEG14976.1 - 0.37 10.1 10.1 0.025 14.0 3.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3087 PF11286.8 KEG14976.1 - 0.68 9.4 2.8 0.8 9.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) CLAMP PF14769.6 KEG14978.1 - 1.4e-29 102.4 1.0 2.3e-29 101.8 1.0 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 YtzH PF14165.6 KEG14978.1 - 0.22 11.9 0.2 0.22 11.9 0.2 1.8 2 0 0 2 2 2 0 YtzH-like protein Sirohm_synth_C PF14823.6 KEG14978.1 - 1.1 8.9 4.7 11 5.8 0.1 3.1 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal Ribonuclease_3 PF00636.26 KEG14979.1 - 0.016 15.8 0.0 0.15 12.7 0.0 2.4 1 1 0 1 1 1 0 Ribonuclease III domain WSD PF15613.6 KEG14980.1 - 2.1e-12 47.4 0.1 2.1e-12 47.4 0.1 3.5 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KEG14980.1 - 0.002 18.4 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KEG14980.1 - 0.0033 16.9 0.0 0.0083 15.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Merozoite_SPAM PF07133.11 KEG14980.1 - 0.013 15.5 36.8 0.58 10.1 0.9 2.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF913 PF06025.12 KEG14980.1 - 3.8 6.4 12.1 0.54 9.2 1.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SART-1 PF03343.13 KEG14980.1 - 9.7 4.6 37.4 0.058 12.0 25.4 2.3 2 0 0 2 2 2 0 SART-1 family Ribosomal_L24e PF01246.20 KEG14981.1 - 2.8e-21 75.5 1.4 2.8e-21 75.5 1.4 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e HORMA PF02301.18 KEG14982.1 - 1.2e-52 178.6 0.0 1.8e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 HORMA domain DUF5345 PF17280.2 KEG14982.1 - 0.12 12.4 0.2 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) SPEG_u2 PF16650.5 KEG14983.1 - 4.7 7.5 5.6 36 4.6 0.3 2.5 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein CorA PF01544.18 KEG14984.1 - 2.8e-10 40.0 0.1 1.5e-08 34.3 0.0 2.5 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein Sec8_exocyst PF04048.14 KEG14984.1 - 0.23 11.3 0.5 0.63 9.9 0.3 1.8 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Exo_endo_phos PF03372.23 KEG14985.1 - 9.9e-05 22.0 0.0 0.0019 17.8 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Memo PF01875.17 KEG14986.1 - 9.5e-61 205.3 0.0 1.2e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.18 KEG14987.1 - 4e-08 32.9 1.3 2.1e-07 30.6 1.3 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PKHD_C PF18331.1 KEG14987.1 - 0.017 15.1 1.7 0.028 14.5 0.6 2.0 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain COQ7 PF03232.13 KEG14989.1 - 0.00011 22.0 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Glyco_transf_22 PF03901.17 KEG14990.1 - 1e-96 324.7 27.6 1.4e-96 324.3 27.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family COX4_pro_2 PF07835.12 KEG14990.1 - 6.7 6.9 9.2 1.5 9.0 1.2 3.5 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV PP2C PF00481.21 KEG14993.1 - 6.7e-15 55.4 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF5393 PF17371.2 KEG14994.1 - 3e-25 88.5 13.8 1.3e-21 76.4 2.0 3.4 3 1 0 3 3 3 3 Family of unknown function (DUF5393) S4 PF01479.25 KEG14995.1 - 3.5e-12 45.8 0.2 7.7e-12 44.7 0.2 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KEG14995.1 - 6.2e-07 30.2 0.2 1.4e-06 29.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Pkinase PF00069.25 KEG14996.1 - 2.1e-41 142.0 0.0 1.4e-29 103.3 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG14996.1 - 2.1e-23 82.9 0.0 4.7e-16 58.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase AF-4 PF05110.13 KEG14996.1 - 1 7.4 9.8 2.3 6.2 9.8 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein EF-hand_7 PF13499.6 KEG15000.1 - 9.2e-16 58.1 0.3 4.8e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEG15000.1 - 5.6e-13 47.4 0.9 0.0089 15.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KEG15000.1 - 2e-12 46.0 2.1 0.0014 18.4 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KEG15000.1 - 9e-11 40.8 0.9 0.009 15.5 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KEG15000.1 - 4.3e-07 29.7 1.1 0.17 11.7 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 KEG15000.1 - 0.022 14.6 0.0 5.2 7.0 0.0 3.0 2 1 0 2 2 2 0 EF hand DUF5580 PF17743.1 KEG15000.1 - 0.022 13.3 0.0 1.5 7.3 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KEG15000.1 - 0.15 12.4 0.0 9.3 6.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain CYSTM PF12734.7 KEG15000.1 - 0.34 11.3 3.5 0.65 10.4 3.5 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance HECT PF00632.25 KEG15001.1 - 5.3e-53 180.5 0.0 8.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KEG15001.1 - 5.4e-34 116.9 1.3 1.1e-15 57.8 0.0 3.6 3 0 0 3 3 3 3 SPRY domain Laminin_G_3 PF13385.6 KEG15001.1 - 1.5e-10 41.5 1.2 2.1e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Serglycin PF04360.12 KEG15001.1 - 0.12 12.3 0.5 0.36 10.8 0.5 1.7 1 0 0 1 1 1 0 Serglycin Ran_BP1 PF00638.18 KEG15002.1 - 1.3e-26 93.3 0.6 1.6e-26 93.0 0.6 1.1 1 0 0 1 1 1 1 RanBP1 domain SEO_C PF14577.6 KEG15002.1 - 0.056 12.9 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Lactamase_B PF00753.27 KEG15003.1 - 1e-05 25.7 0.1 2.3e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEG15003.1 - 0.018 14.6 1.4 0.11 12.0 0.8 2.4 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Toxin_9 PF02819.15 KEG15004.1 - 0.028 14.7 1.1 0.051 13.9 1.1 1.3 1 0 0 1 1 1 0 Spider toxin AAA PF00004.29 KEG15006.1 - 5.2e-14 52.8 0.0 1.5e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG15006.1 - 0.00045 20.7 1.4 0.0024 18.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEG15006.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IQ PF00612.27 KEG15006.1 - 0.0093 15.7 0.8 0.0093 15.7 0.8 3.3 3 0 0 3 3 3 1 IQ calmodulin-binding motif AAA_5 PF07728.14 KEG15006.1 - 0.053 13.5 0.0 0.36 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KEG15006.1 - 0.087 13.2 0.5 0.75 10.1 0.0 2.8 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.6 KEG15006.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.7 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 KEG15006.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KEG15006.1 - 0.47 11.0 2.1 1.9 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain PhoLip_ATPase_C PF16212.5 KEG15008.1 - 5.1e-60 203.3 17.9 5.1e-60 203.3 17.9 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEG15008.1 - 3.5e-24 84.3 0.3 1.4e-23 82.3 0.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KEG15008.1 - 1.1e-11 44.6 0.0 8.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEG15008.1 - 3.2e-09 37.4 0.6 5.3e-05 23.6 0.3 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEG15008.1 - 7.7e-09 35.3 0.1 1.3e-07 31.4 0.0 3.1 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEG15008.1 - 0.041 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 KEG15009.1 - 4.3e-08 32.9 0.0 2.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.6 KEG15009.1 - 1.5 9.3 6.9 2.5 8.5 6.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dicty_REP PF05086.12 KEG15010.1 - 0.027 12.5 1.1 0.042 11.8 1.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KEG15010.1 - 8.7 6.3 19.6 0.087 12.8 10.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Gtr1_RagA PF04670.12 KEG15011.1 - 4.7e-90 301.0 0.0 6.6e-90 300.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KEG15011.1 - 2e-07 31.3 0.0 1e-06 29.0 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEG15011.1 - 6.1e-06 25.9 0.0 1.4e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KEG15011.1 - 0.00019 20.9 0.0 0.00058 19.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Metallophos PF00149.28 KEG15012.1 - 2.5e-25 90.2 0.0 3.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.26 KEG15013.1 - 3e-16 59.3 0.0 3.2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEG15013.1 - 0.0076 16.5 0.0 0.0082 16.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain LD_cluster2 PF18163.1 KEG15013.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 SLOG cluster2 Tcp10_C PF07202.13 KEG15014.1 - 5.8e-28 98.0 0.0 5.8e-28 98.0 0.0 2.4 3 0 0 3 3 3 1 T-complex protein 10 C-terminus DUF3439 PF11921.8 KEG15015.1 - 0.079 12.9 1.1 0.2 11.6 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nuf2 PF03800.14 KEG15015.1 - 0.14 12.3 1.9 0.41 10.7 0.2 2.7 2 0 0 2 2 2 0 Nuf2 family Img2 PF05046.14 KEG15015.1 - 0.17 12.2 1.3 9 6.7 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) RAMP4 PF06624.12 KEG15015.1 - 0.48 10.5 2.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Cache_3-Cache_2 PF17201.4 KEG15015.1 - 0.55 9.5 16.7 0.11 11.7 2.1 3.9 3 0 0 3 3 3 0 Cache 3/Cache 2 fusion domain PID_2 PF14719.6 KEG15015.1 - 1.1 9.1 3.7 0.64 9.9 0.1 2.5 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Spt20 PF12090.8 KEG15015.1 - 1.7 8.2 13.4 0.49 10.0 7.3 2.7 2 0 0 2 2 2 0 Spt20 family RasGAP PF00616.19 KEG15015.1 - 1.9 8.2 11.0 0.67 9.6 0.3 3.8 3 1 1 4 4 4 0 GTPase-activator protein for Ras-like GTPase Kinesin PF00225.23 KEG15016.1 - 3.1e-91 305.8 0.0 9.2e-91 304.2 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG15016.1 - 2.5e-13 50.2 0.0 7.5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 KEG15016.1 - 7.7e-05 23.1 2.4 0.00019 21.8 0.7 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KEG15016.1 - 0.00013 22.0 0.5 0.00033 20.7 0.5 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2075 PF09848.9 KEG15016.1 - 0.1 11.8 0.8 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CdiA_C PF18451.1 KEG15016.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain CDC50 PF03381.15 KEG15017.1 - 2e-76 257.2 0.0 2.8e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Rep_fac-A_3 PF08661.11 KEG15020.1 - 6.7e-08 32.8 0.0 8.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 BHD_3 PF10405.9 KEG15021.1 - 8.9e-13 48.5 0.0 2.5e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KEG15021.1 - 3.5e-12 46.0 0.7 1e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 KEG15021.1 - 1.4e-10 41.0 0.1 4.7e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 KEG15021.1 - 2e-05 25.5 0.4 0.00082 20.3 0.1 3.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 peroxidase PF00141.23 KEG15022.1 - 3.9e-05 23.5 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.21 KEG15023.1 - 7.1e-22 78.3 0.1 1.5e-21 77.2 0.1 1.6 1 1 0 1 1 1 1 Acyl transferase domain SUIM_assoc PF16619.5 KEG15024.1 - 0.66 10.1 10.8 0.53 10.4 7.5 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 STG PF15809.5 KEG15027.1 - 0.41 10.7 4.2 1.2 9.2 0.1 2.4 3 0 0 3 3 3 0 Simian taste bud-specific gene product family FYVE PF01363.21 KEG15028.1 - 1.4e-20 73.2 8.6 2.4e-20 72.4 8.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 KEG15028.1 - 0.14 12.4 10.3 0.11 12.8 6.2 2.6 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 KEG15028.1 - 0.35 11.1 7.0 0.12 12.6 3.8 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C2H2_11 PF16622.5 KEG15028.1 - 2.1 8.2 8.7 0.25 11.1 1.2 2.6 1 1 1 2 2 2 0 zinc-finger C2H2-type zf-RING_5 PF14634.6 KEG15028.1 - 2.4 8.2 10.4 7.2 6.7 6.1 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Ribosomal_L32p PF01783.23 KEG15028.1 - 7.7 6.9 8.5 2 8.7 3.9 2.3 2 1 0 2 2 2 0 Ribosomal L32p protein family CAP_N PF01213.19 KEG15029.1 - 5.7 6.3 6.0 1 8.8 1.9 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SMC_N PF02463.19 KEG15031.1 - 4.3e-56 189.8 0.0 1.6e-54 184.7 0.0 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEG15031.1 - 4.9e-29 101.0 0.0 1.9e-28 99.1 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KEG15031.1 - 1.3e-13 52.0 8.0 1.3e-13 52.0 8.0 5.9 3 2 1 4 4 2 1 AAA domain AAA_21 PF13304.6 KEG15031.1 - 6.1e-13 49.2 6.3 5.1e-06 26.5 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEG15031.1 - 1.4e-10 41.4 16.2 2.8e-10 40.4 7.8 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEG15031.1 - 2.8e-09 36.6 0.0 5.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KEG15031.1 - 0.0024 17.9 3.5 0.33 11.0 0.0 3.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KEG15031.1 - 0.024 14.9 0.0 0.1 12.9 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2939 PF11159.8 KEG15031.1 - 0.041 14.3 4.5 5.8 7.4 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) DUF4806 PF16064.5 KEG15031.1 - 0.35 11.2 3.6 17 5.8 0.0 3.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4806) AAA PF00004.29 KEG15031.1 - 0.95 9.9 7.4 12 6.3 0.0 4.9 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG15031.1 - 7.2 6.9 11.4 12 6.2 0.0 5.3 5 1 1 6 6 6 0 AAA domain KH_1 PF00013.29 KEG15033.1 - 0.011 15.5 0.1 0.032 14.1 0.1 1.8 1 0 0 1 1 1 0 KH domain KH_8 PF17903.1 KEG15033.1 - 0.026 14.6 0.1 0.13 12.4 0.1 2.0 1 1 0 1 1 1 0 Krr1 KH1 domain Baculo_PEP_C PF04513.12 KEG15034.1 - 0.15 12.1 3.0 15 5.6 0.7 3.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lin-8 PF03353.15 KEG15034.1 - 0.61 9.6 10.7 1.7 8.1 10.7 1.8 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 KEG15034.1 - 1.8 7.2 5.5 3.7 6.2 5.5 1.5 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 KEG15034.1 - 4.1 6.9 16.7 7.8 6.0 16.7 1.4 1 0 0 1 1 1 0 Spt20 family SelP_N PF04592.14 KEG15034.1 - 7.1 6.0 23.0 14 5.0 23.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Exonuc_VII_L PF02601.15 KEG15034.1 - 9.4 5.7 24.5 3.1 7.3 3.0 3.2 2 1 0 2 2 2 0 Exonuclease VII, large subunit CRAL_TRIO PF00650.20 KEG15035.1 - 1.5e-22 80.0 0.5 3.4e-22 78.9 0.2 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEG15035.1 - 6.4e-08 32.7 1.2 1.7e-07 31.3 1.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KEG15035.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain MatE PF01554.18 KEG15036.1 - 1.4e-38 132.0 29.7 3.3e-20 72.4 9.8 2.2 2 0 0 2 2 2 2 MatE MatE PF01554.18 KEG15037.1 - 2e-34 118.6 30.2 3.1e-20 72.4 7.9 2.7 2 1 0 2 2 2 2 MatE FUSC_2 PF13515.6 KEG15038.1 - 2.9e-06 27.4 3.3 2.9e-06 27.4 3.3 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 KEG15038.1 - 4.5 7.4 11.8 0.13 12.4 4.4 2.1 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 XPG_N PF00752.17 KEG15039.1 - 2.2e-21 76.2 0.0 4.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KEG15039.1 - 6.2e-19 68.2 0.1 1.3e-18 67.2 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KEG15039.1 - 1.1e-10 41.4 0.4 2.2e-10 40.5 0.4 1.5 1 0 0 1 1 1 1 XPG domain containing Methyltransf_23 PF13489.6 KEG15040.1 - 6.6e-25 87.8 0.0 9.2e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEG15040.1 - 8.9e-12 45.6 0.0 3.1e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEG15040.1 - 1e-07 32.5 0.2 3.6e-07 30.7 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEG15040.1 - 2.6e-07 31.2 0.1 2.1e-06 28.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG15040.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Pro_isomerase PF00160.21 KEG15041.1 - 5.6e-33 114.4 0.0 6.3e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3659 PF12396.8 KEG15041.1 - 0.081 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) NifU_N PF01592.16 KEG15042.1 - 4.4e-47 159.4 0.0 5.6e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DNA_pol_phi PF04931.13 KEG15043.1 - 0.29 9.2 9.2 0.35 8.9 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KEG15043.1 - 0.63 9.3 5.7 0.72 9.1 5.7 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 KEG15043.1 - 1.1 8.9 7.3 1.7 8.3 7.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 KEG15043.1 - 1.2 8.2 2.6 1.5 7.8 2.6 1.1 1 0 0 1 1 1 0 Pes-10 Rho_RNA_bind PF07497.12 KEG15045.1 - 0.079 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Arm_vescicular PF18770.1 KEG15045.1 - 0.47 10.4 4.8 14 5.7 0.0 3.7 3 0 0 3 3 3 0 Armadillo tether-repeat of vescicular transport factor DZR PF12773.7 KEG15045.1 - 1 9.5 100.5 0.084 12.9 8.7 8.7 4 2 2 7 7 7 0 Double zinc ribbon NDUF_B7 PF05676.13 KEG15046.1 - 1.4e-07 31.1 0.3 2.5e-07 30.3 0.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) NAD_binding_4 PF07993.12 KEG15047.1 - 4.8e-66 222.6 0.0 6.3e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 KEG15047.1 - 4.7e-16 58.8 0.1 1e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KEG15047.1 - 5.9e-06 25.9 0.0 2.2e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEG15047.1 - 0.00071 19.1 0.1 0.17 11.2 0.0 2.5 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEG15047.1 - 0.0013 17.8 0.2 1.6 7.7 0.0 2.8 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEG15047.1 - 0.0045 16.1 0.1 0.084 12.0 0.1 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEG15047.1 - 0.0055 15.9 0.3 0.16 11.1 0.2 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Amastin PF07344.11 KEG15049.1 - 3.3e-08 33.5 5.1 3.3e-08 33.5 5.1 1.8 1 1 1 2 2 2 1 Amastin surface glycoprotein Oxidored_q3 PF00499.20 KEG15049.1 - 0.029 14.1 7.9 0.084 12.6 6.3 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SHD1 PF03983.12 KEG15049.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 FAD_binding_2 PF00890.24 KEG15050.1 - 2e-114 382.9 1.0 2e-114 382.9 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 KEG15050.1 - 1.6e-38 131.6 1.3 2.2e-38 131.1 1.3 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KEG15050.1 - 0.0011 18.2 0.1 0.17 11.1 0.1 2.7 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 KEG15050.1 - 0.002 17.4 0.6 0.002 17.4 0.6 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEG15050.1 - 0.0032 16.6 2.6 0.12 11.4 2.5 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KEG15050.1 - 0.01 15.5 0.8 0.072 12.7 0.8 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEG15050.1 - 0.017 14.2 2.1 1.7 7.6 0.5 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KEG15050.1 - 0.021 13.6 0.2 0.045 12.4 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GST_N_4 PF17172.4 KEG15051.1 - 1.4e-14 54.6 0.0 2.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEG15051.1 - 2.3e-10 40.1 0.0 4.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEG15051.1 - 2.4e-06 27.4 0.5 4.4e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEG15051.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KEG15052.1 - 2.4e-16 60.3 0.0 1.1e-15 58.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KEG15052.1 - 1.2e-09 38.6 0.0 4.4e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KEG15052.1 - 4.2e-08 32.9 0.0 8.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEG15052.1 - 0.019 15.0 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3175 PF11373.8 KEG15052.1 - 0.059 13.5 0.2 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) GST_N_4 PF17172.4 KEG15053.1 - 1.2e-26 93.4 0.0 2.3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KEG15053.1 - 1.1e-12 48.4 0.0 1.8e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KEG15053.1 - 8.3e-09 35.1 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEG15053.1 - 1.3e-08 34.7 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEG15053.1 - 3.5e-05 24.1 0.0 9.5e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEG15053.1 - 0.0072 16.6 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEG15053.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RUN PF02759.19 KEG15054.1 - 0.0068 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 RUN domain UBA PF00627.31 KEG15055.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 KEG15055.1 - 2.6e-05 24.3 1.0 4.7e-05 23.4 1.0 1.5 1 1 0 1 1 1 1 Rhomboid family CUE PF02845.16 KEG15055.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF1751 PF08551.10 KEG15055.1 - 0.051 14.2 0.9 0.1 13.2 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF1263 PF06882.12 KEG15056.1 - 1.7 8.7 7.0 0.42 10.7 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1263) REV PF00424.18 KEG15060.1 - 0.72 9.9 7.8 0.28 11.2 4.0 1.9 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) MutL_C PF08676.11 KEG15061.1 - 0.0034 17.1 0.0 0.036 13.8 0.0 2.5 3 0 0 3 3 3 1 MutL C terminal dimerisation domain Pkinase PF00069.25 KEG15062.1 - 2.1e-28 99.4 0.0 8.6e-14 51.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15062.1 - 1.2e-07 31.3 0.0 0.0014 17.9 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase SlyX PF04102.12 KEG15065.1 - 0.0028 18.3 3.3 0.057 14.0 2.9 2.6 2 0 0 2 2 2 1 SlyX APG6_N PF17675.1 KEG15065.1 - 0.0039 17.7 4.9 0.0087 16.6 4.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 KEG15065.1 - 0.015 15.8 0.9 0.039 14.4 0.9 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 KEG15065.1 - 0.017 14.0 1.6 0.029 13.2 1.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 KEG15065.1 - 0.3 10.9 1.9 0.59 9.9 1.9 1.4 1 0 0 1 1 1 0 Septum formation initiator MCC-bdg_PDZ PF10506.9 KEG15065.1 - 0.55 10.3 3.6 16 5.6 0.3 3.0 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome zf-C4H2 PF10146.9 KEG15065.1 - 1.2 9.4 6.9 6.7 7.0 6.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Methyltransf_16 PF10294.9 KEG15066.1 - 1.1e-21 77.4 0.2 8.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 KEG15066.1 - 0.0091 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KEG15066.1 - 0.039 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 KEG15066.1 - 0.046 13.3 0.1 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KEG15066.1 - 0.049 14.3 0.3 5.7 7.7 0.1 3.0 3 0 0 3 3 3 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.6 KEG15067.1 - 8.3e-16 58.0 4.7 1.1e-07 32.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEG15067.1 - 1.8e-14 53.7 3.9 2.3e-08 34.1 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KEG15067.1 - 0.0096 16.3 0.2 11 6.5 0.0 3.1 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF384 PF04064.13 KEG15067.1 - 1.3 9.0 6.1 0.66 9.9 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF384) EHD_N PF16880.5 KEG15068.1 - 0.036 13.9 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 N-terminal EH-domain containing protein IMPDH PF00478.25 KEG15069.1 - 5e-142 473.0 4.1 5.6e-142 472.8 4.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KEG15069.1 - 1.8e-14 53.9 0.1 9.3e-06 26.0 0.1 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KEG15069.1 - 1.9e-06 27.1 5.3 4e-06 26.1 5.3 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KEG15069.1 - 3.7e-06 26.6 8.9 0.00088 18.8 4.6 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 KEG15069.1 - 4.6e-05 23.0 1.8 0.015 14.8 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.17 KEG15069.1 - 0.0018 17.5 1.5 0.0032 16.7 1.5 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KEG15069.1 - 0.0024 17.2 3.6 0.0026 17.1 1.0 2.2 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KEG15069.1 - 0.0042 16.3 2.9 0.094 11.9 0.3 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KEG15069.1 - 0.12 11.8 0.5 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 KEG15069.1 - 0.15 11.5 6.7 2.5 7.5 0.1 3.6 4 1 0 4 4 4 0 PcrB family Lysine_decarbox PF03641.14 KEG15070.1 - 1e-28 100.0 0.6 1.6e-28 99.4 0.6 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KEG15070.1 - 1.2e-12 47.7 0.6 1.7e-12 47.2 0.6 1.2 1 0 0 1 1 1 1 SLOG cluster4 family ABM PF03992.16 KEG15070.1 - 1.2e-09 38.1 0.1 3.6e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MbeD_MobD PF04899.12 KEG15070.1 - 0.16 12.1 1.4 0.37 10.9 0.2 2.2 2 0 0 2 2 2 0 MbeD/MobD like Cortex-I_coil PF09304.10 KEG15071.1 - 7.5e-05 22.9 5.5 7.5e-05 22.9 5.5 4.3 2 1 2 4 4 3 1 Cortexillin I, coiled coil Sec34 PF04136.15 KEG15071.1 - 0.02 14.8 31.7 0.032 14.1 7.0 3.6 2 1 1 3 3 3 0 Sec34-like family DUF2274 PF10038.9 KEG15071.1 - 0.028 14.9 1.5 8.9 6.8 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2274) DASH_Ask1 PF08655.10 KEG15071.1 - 0.08 12.8 3.4 8.5 6.3 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Ask1 RNA_pol_Rpb2_4 PF04566.13 KEG15071.1 - 0.1 12.9 1.4 3.4 8.0 0.2 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 DUF948 PF06103.11 KEG15071.1 - 0.1 12.9 5.3 9.4 6.6 0.2 3.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Gsf2 PF11055.8 KEG15071.1 - 0.22 10.3 4.2 0.52 9.0 4.2 1.6 1 0 0 1 1 1 0 Glucose signalling factor 2 Baculo_PEP_C PF04513.12 KEG15071.1 - 1.4 8.9 6.9 20 5.2 0.1 3.9 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRA PF06589.11 KEG15071.1 - 3 7.9 14.6 4 7.6 9.2 2.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF2894 PF11445.8 KEG15071.1 - 7.1 7.1 27.4 1.1 9.7 6.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2894) MMPL PF03176.15 KEG15071.1 - 9.4 5.1 11.0 4.1 6.2 2.0 2.4 2 1 0 2 2 2 0 MMPL family Kinesin PF00225.23 KEG15072.1 - 2e-105 352.4 0.0 8.1e-105 350.4 0.0 2.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG15072.1 - 1.1e-25 90.3 0.0 1.1e-25 90.3 0.0 2.8 4 1 0 4 4 2 1 Microtubule binding DUF4795 PF16043.5 KEG15072.1 - 0.0032 17.1 33.8 0.074 12.6 18.6 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4795) Filament PF00038.21 KEG15072.1 - 0.0043 16.7 5.2 0.0043 16.7 5.2 4.7 2 2 2 4 4 4 2 Intermediate filament protein Herpes_UL35 PF04496.12 KEG15072.1 - 0.031 14.6 0.4 1.2 9.4 0.0 3.1 1 1 2 3 3 3 0 Herpesvirus UL35 family HYR PF02494.16 KEG15072.1 - 0.063 13.6 0.1 0.36 11.2 0.0 2.3 3 0 0 3 3 1 0 HYR domain Methyltransf_25 PF13649.6 KEG15072.1 - 0.19 12.4 6.0 2.2 9.1 0.3 3.8 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 KEG15072.1 - 0.21 12.3 0.5 12 6.6 0.2 3.2 2 0 0 2 2 2 0 Methyltransferase domain ApoO PF09769.9 KEG15072.1 - 0.25 11.3 9.0 0.56 10.2 2.1 3.2 3 0 0 3 3 2 0 Apolipoprotein O Stork_head PF10264.9 KEG15072.1 - 1 9.5 3.1 2.3 8.4 0.2 2.9 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain COMP PF11598.8 KEG15072.1 - 1.1 9.8 8.0 29 5.2 1.4 4.2 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Spc42p PF11544.8 KEG15072.1 - 1.3 9.1 18.0 0.033 14.2 3.6 3.9 3 0 0 3 3 3 0 Spindle pole body component Spc42p NTP_transf_4 PF13562.6 KEG15072.1 - 1.3 9.2 6.6 4 7.6 2.4 3.2 2 1 0 3 3 3 0 Sugar nucleotidyl transferase GSCFA PF08885.11 KEG15072.1 - 3.5 7.2 9.0 0.65 9.6 1.3 3.0 2 1 0 3 3 3 0 GSCFA family MnmE_helical PF12631.7 KEG15072.1 - 3.6 7.7 25.5 3.3 7.8 14.9 3.2 1 1 1 2 2 2 0 MnmE helical domain Spc7 PF08317.11 KEG15072.1 - 3.7 6.4 53.5 1.5 7.7 14.8 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Lebercilin PF15619.6 KEG15072.1 - 4.4 6.9 43.9 5.6 6.6 24.9 2.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 KEG15072.1 - 8 5.7 36.2 32 3.7 16.4 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 KEG15073.1 - 0.0093 16.1 8.0 0.013 15.7 4.7 2.4 2 0 0 2 2 2 1 Tropomyosin like RRM_1 PF00076.22 KEG15073.1 - 0.01 15.6 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomyosin PF00261.20 KEG15073.1 - 0.013 14.9 3.8 0.013 14.9 3.8 1.7 2 0 0 2 2 2 0 Tropomyosin ACT_5 PF13710.6 KEG15073.1 - 0.091 12.6 1.4 0.98 9.3 0.8 2.7 3 0 0 3 3 3 0 ACT domain ATG16 PF08614.11 KEG15073.1 - 0.24 11.6 12.7 0.084 13.1 7.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 KEG15073.1 - 0.32 11.4 9.7 1.9 8.9 0.2 3.9 2 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 KEG15073.1 - 1.7 8.5 6.4 0.24 11.2 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 KEG15073.1 - 2.1 8.7 10.8 3.9 7.8 1.0 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF1192 PF06698.11 KEG15073.1 - 7.4 6.7 6.9 7.6 6.7 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) G-patch PF01585.23 KEG15074.1 - 2.7e-13 49.5 0.3 5.3e-13 48.6 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KEG15074.1 - 0.0032 17.5 0.1 0.0097 16.0 0.1 1.8 1 0 0 1 1 1 1 G-patch domain DUF755 PF05501.11 KEG15074.1 - 0.0082 16.4 9.2 0.012 15.9 9.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) DUF4228 PF14009.6 KEG15074.1 - 0.013 15.9 3.7 0.017 15.5 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SR-25 PF10500.9 KEG15074.1 - 0.036 13.7 11.6 0.054 13.1 11.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 KEG15074.1 - 0.037 12.1 2.5 0.036 12.2 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KEG15074.1 - 0.085 10.9 2.6 0.11 10.6 2.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi SWIRM-assoc_2 PF16496.5 KEG15074.1 - 0.11 11.3 3.0 0.16 10.8 3.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Nucleo_P87 PF07267.11 KEG15074.1 - 0.17 10.7 3.5 0.19 10.5 3.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AF-4 PF05110.13 KEG15074.1 - 0.28 9.2 11.3 0.34 9.0 11.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 KEG15074.1 - 0.57 8.9 2.8 0.67 8.7 2.8 1.0 1 0 0 1 1 1 0 Presenilin DTHCT PF08070.11 KEG15074.1 - 1.1 10.1 15.3 5.5 7.8 15.4 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region Pkinase PF00069.25 KEG15076.1 - 3.8e-58 196.9 0.0 4.4e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15076.1 - 3.5e-21 75.7 0.0 5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KEG15076.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KEG15076.1 - 0.0023 17.9 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEG15076.1 - 0.077 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KEG15076.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Mo25 PF08569.11 KEG15077.1 - 0.09 12.1 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Mo25-like Ribosomal_S2 PF00318.20 KEG15077.1 - 0.11 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S2 OmpH PF03938.14 KEG15077.1 - 0.38 11.1 4.8 9 6.6 0.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Snapin_Pallidin PF14712.6 KEG15077.1 - 0.95 9.9 4.5 0.36 11.3 1.2 2.0 2 0 0 2 2 2 0 Snapin/Pallidin CoaE PF01121.20 KEG15078.1 - 4.4e-24 85.1 2.6 2.8e-23 82.5 2.6 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase NTF2 PF02136.20 KEG15079.1 - 4.2e-07 30.5 0.0 7.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KEG15079.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF35_N PF12172.8 KEG15080.1 - 0.15 11.9 0.8 0.15 11.9 0.8 2.7 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF4379 PF14311.6 KEG15081.1 - 3.3e-17 62.6 7.8 5.3e-08 33.1 0.8 2.9 2 1 0 2 2 2 2 Probable Zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KEG15081.1 - 0.031 14.3 2.3 0.031 14.3 2.3 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 KEG15081.1 - 0.041 13.6 5.9 21 4.9 0.0 3.7 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF5313 PF17240.2 KEG15081.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) HNH_5 PF14279.6 KEG15081.1 - 0.1 12.5 0.5 28 4.7 0.0 3.3 3 0 0 3 3 3 0 HNH endonuclease Elf1 PF05129.13 KEG15081.1 - 0.43 10.7 2.8 3.6 7.7 0.2 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 KEG15081.1 - 4.6 7.4 8.1 35 4.5 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon DnaJ PF00226.31 KEG15082.1 - 2.2e-15 56.5 0.0 4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ATP-synt_8 PF00895.20 KEG15082.1 - 0.076 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 FtsH_ext PF06480.15 KEG15082.1 - 0.091 13.1 0.7 19 5.7 0.0 2.7 2 1 1 3 3 3 0 FtsH Extracellular FAM221 PF14753.6 KEG15083.1 - 3.6e-15 56.1 10.7 9.5e-13 48.2 2.8 2.8 3 0 0 3 3 3 2 Protein FAM221A/B NOB1_Zn_bind PF08772.11 KEG15083.1 - 0.0031 17.6 1.6 0.0031 17.6 1.6 2.8 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 KEG15083.1 - 0.028 14.4 0.5 0.028 14.4 0.5 3.4 3 1 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KEG15083.1 - 4.5 6.8 14.2 0.11 12.0 2.7 3.0 2 0 0 2 2 2 0 zinc-ribbon domain ATP12 PF07542.11 KEG15084.1 - 1e-19 70.9 0.0 2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein FAA_hydro_N_2 PF18288.1 KEG15084.1 - 0.087 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Peptidase_C13 PF01650.18 KEG15085.1 - 1.2e-35 123.3 0.0 1.5e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.15 KEG15086.1 - 4.5e-82 275.5 0.0 5.8e-82 275.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG15086.1 - 2.9e-08 33.3 0.0 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KEG15086.1 - 0.0049 16.2 0.0 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3884 PF13024.6 KEG15086.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Nuc_sug_transp PF04142.15 KEG15089.1 - 1.9e-80 270.4 12.7 2.7e-80 269.9 12.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KEG15089.1 - 1.1e-08 34.6 6.7 1.7e-08 34.0 6.7 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEG15089.1 - 3.5e-08 33.7 26.6 2.5e-05 24.5 6.9 2.9 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KEG15089.1 - 5.3e-05 22.6 13.7 0.00016 21.1 13.7 2.0 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KEG15089.1 - 0.00093 18.2 2.7 0.00093 18.2 2.7 2.1 2 1 1 3 3 3 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KEG15089.1 - 0.26 10.6 12.9 0.014 14.8 3.4 2.7 3 1 0 3 3 3 0 Triose-phosphate Transporter family PAP2 PF01569.21 KEG15092.1 - 5.1e-23 81.3 4.2 1.1e-22 80.2 2.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KEG15092.1 - 1.3e-05 24.9 1.4 0.0011 18.7 1.4 2.8 1 1 0 1 1 1 1 PAP2 superfamily CbiM PF01891.16 KEG15092.1 - 0.036 13.9 0.2 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region Yip1 PF04893.17 KEG15092.1 - 0.45 10.2 7.2 41 3.8 7.2 2.3 1 1 0 1 1 1 0 Yip1 domain Phage_holin_5_2 PF16079.5 KEG15092.1 - 0.58 10.5 3.1 4.3 7.7 0.2 3.0 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V PAP2 PF01569.21 KEG15093.1 - 9e-25 87.0 1.4 1.2e-24 86.6 1.4 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KEG15093.1 - 0.0041 16.8 0.6 0.015 15.0 0.6 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF2505 PF10698.9 KEG15094.1 - 0.19 11.9 1.6 0.32 11.1 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2505) Ubiquitin_2 PF14560.6 KEG15095.1 - 3.6e-24 85.0 0.1 6.1e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KEG15095.1 - 8.5e-23 80.1 1.4 8.8e-23 80.1 0.4 1.5 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 KEG15095.1 - 6e-05 22.7 0.2 0.00063 19.4 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin family PB1 PF00564.24 KEG15095.1 - 0.061 13.3 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 PB1 domain WD40 PF00400.32 KEG15096.1 - 3.9e-42 141.4 20.9 2.8e-07 31.1 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG15096.1 - 6.4e-10 39.2 4.1 0.0064 16.8 0.0 5.5 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEG15096.1 - 0.00089 18.0 5.7 0.62 8.6 0.0 3.8 2 1 1 4 4 4 2 Nucleoporin Nup120/160 MbeD_MobD PF04899.12 KEG15096.1 - 0.026 14.6 2.4 0.12 12.5 0.8 2.6 2 1 1 3 3 3 0 MbeD/MobD like eIF2A PF08662.11 KEG15096.1 - 0.039 13.8 0.1 0.2 11.5 0.0 2.1 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A BLOC1_2 PF10046.9 KEG15096.1 - 0.043 14.1 1.9 0.089 13.1 1.3 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ge1_WD40 PF16529.5 KEG15096.1 - 0.063 12.2 2.6 0.65 8.9 0.0 3.3 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sec34 PF04136.15 KEG15096.1 - 0.072 13.0 4.1 0.16 11.9 4.1 1.6 1 0 0 1 1 1 0 Sec34-like family FlxA PF14282.6 KEG15096.1 - 0.084 12.9 14.4 0.28 11.2 5.5 2.3 1 1 0 2 2 2 0 FlxA-like protein DUF3450 PF11932.8 KEG15096.1 - 0.16 11.3 9.0 0.04 13.2 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BRI3BP PF14965.6 KEG15096.1 - 0.28 10.7 0.9 2 7.9 0.4 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Taxilin PF09728.9 KEG15096.1 - 0.77 8.9 22.1 0.14 11.3 16.0 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 KEG15096.1 - 4.6 7.3 18.7 1.9 8.5 3.8 2.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KEG15096.1 - 5.3 7.1 8.4 18 5.4 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KEG15096.1 - 6.3 5.2 6.6 8.6 4.8 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UDG PF03167.19 KEG15097.1 - 1.6e-19 70.4 0.0 2.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cupin_1 PF00190.22 KEG15097.1 - 0.039 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin BTB_2 PF02214.22 KEG15098.1 - 2e-11 44.1 0.0 3.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Aconitase PF00330.20 KEG15100.1 - 3.5e-179 596.6 0.0 4.9e-179 596.1 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEG15100.1 - 4.6e-43 146.7 0.0 9.5e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain TBCC PF07986.12 KEG15102.1 - 5.6e-38 129.3 0.1 8.3e-38 128.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.10 KEG15102.1 - 2.2e-05 24.6 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.11 KEG15102.1 - 0.0041 16.8 0.4 0.0074 15.9 0.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal LisH_2 PF16045.5 KEG15102.1 - 0.032 13.3 0.1 0.08 12.0 0.1 1.7 1 0 0 1 1 1 0 LisH NOA36 PF06524.12 KEG15102.1 - 0.35 10.2 7.1 0.9 8.8 0.3 2.3 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 KEG15102.1 - 7.4 7.0 21.1 0.67 10.4 1.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TMEM135_C_rich PF15982.5 KEG15103.1 - 9.2e-06 26.3 1.1 2.1e-05 25.1 1.1 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 HupH_C PF04809.13 KEG15104.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region MRP-S26 PF14943.6 KEG15104.1 - 0.26 11.2 11.1 0.42 10.5 11.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 V-ATPase_C PF03223.15 KEG15105.1 - 7.9e-86 288.8 1.3 9e-86 288.6 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Thioredoxin_15 PF18403.1 KEG15105.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain ASH PF15780.5 KEG15106.1 - 7.9e-17 61.3 20.6 0.00066 19.8 0.3 8.8 6 2 2 8 8 8 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KEG15106.1 - 8.2e-09 35.6 4.1 0.001 19.2 0.2 5.2 5 0 0 5 5 5 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 KEG15106.1 - 5.2e-07 29.5 4.7 0.00035 20.4 0.1 5.1 5 1 0 5 5 5 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KEG15106.1 - 0.0011 19.2 8.1 13 6.1 0.0 6.2 7 0 0 7 7 7 3 Transmembrane protein 131-like DUF1573 PF07610.11 KEG15106.1 - 0.0017 18.3 0.1 16 5.6 0.0 5.6 6 0 0 6 6 6 1 Protein of unknown function (DUF1573) fn3_5 PF06280.12 KEG15106.1 - 0.02 15.6 0.9 4.9 7.9 0.1 4.3 5 0 0 5 5 5 0 Fn3-like domain Cnd1 PF12717.7 KEG15108.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 SH3_3 PF08239.11 KEG15109.1 - 0.00031 21.0 0.1 0.26 11.6 0.0 2.8 2 0 0 2 2 2 2 Bacterial SH3 domain ABC_membrane_2 PF06472.15 KEG15110.1 - 2.6e-29 102.5 1.4 4.3e-29 101.8 1.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEG15110.1 - 8.1e-17 62.0 0.0 2.3e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KEG15110.1 - 5.1e-07 29.3 0.1 1.2e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 KEG15110.1 - 4.2e-06 26.6 2.0 6.2e-06 26.1 2.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 KEG15110.1 - 0.0072 16.7 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 KEG15110.1 - 0.0093 16.2 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KEG15110.1 - 0.0097 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 KEG15110.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 KEG15110.1 - 0.014 14.7 0.2 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_22 PF13401.6 KEG15110.1 - 0.017 15.4 0.3 0.29 11.4 0.3 2.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEG15110.1 - 0.03 14.8 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3198 PF11433.8 KEG15110.1 - 0.048 13.6 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) AAA_15 PF13175.6 KEG15110.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Vasohibin PF14822.6 KEG15111.1 - 1.3e-57 194.8 0.1 2.5e-57 194.0 0.1 1.3 1 0 0 1 1 1 1 Vasohibin Brix PF04427.18 KEG15112.1 - 4e-28 98.8 0.2 7e-28 98.1 0.2 1.4 1 0 0 1 1 1 1 Brix domain CT47 PF15623.6 KEG15112.1 - 0.43 10.4 3.5 0.61 9.9 3.5 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 PGM_PMM_I PF02878.16 KEG15114.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PfkB PF00294.24 KEG15115.1 - 8.1e-67 225.6 0.2 9.3e-67 225.5 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KEG15115.1 - 2.7e-10 40.0 0.0 4.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DnaJ PF00226.31 KEG15116.1 - 7e-24 83.7 0.8 1.2e-23 83.0 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4118 PF13493.6 KEG15116.1 - 0.2 11.4 6.4 0.36 10.7 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Apolipoprotein PF01442.18 KEG15117.1 - 1.6 8.6 13.2 6 6.7 13.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FliT PF05400.13 KEG15117.1 - 2.1 9.2 14.4 2.9 8.8 4.1 2.6 2 1 0 2 2 2 0 Flagellar protein FliT HSCB_C PF07743.13 KEG15117.1 - 3.6 8.2 10.6 1.3e+02 3.1 10.6 2.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain APG9 PF04109.16 KEG15118.1 - 2.1e-78 264.5 11.2 2.7e-78 264.1 11.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Nup96 PF12110.8 KEG15119.1 - 7.1e-28 97.6 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KEG15119.1 - 1.7e-14 54.2 0.0 1.3e-13 51.3 0.0 2.2 1 1 0 1 1 1 1 Nucleoporin autopeptidase Phage_TAC_3 PF06896.11 KEG15120.1 - 0.012 16.2 0.1 0.016 15.7 0.1 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC Imm-NTF2 PF15655.6 KEG15121.1 - 0.017 15.4 0.1 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 NTF2 fold immunity protein AAA PF00004.29 KEG15122.1 - 5.3e-37 127.2 0.0 1.5e-35 122.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG15122.1 - 6e-05 22.8 1.9 9.7e-05 22.1 0.4 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KEG15122.1 - 0.00012 22.5 0.0 0.037 14.4 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KEG15122.1 - 0.00023 21.2 0.0 0.0082 16.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KEG15122.1 - 0.0031 17.5 0.0 0.015 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEG15122.1 - 0.01 16.0 0.0 0.079 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KEG15122.1 - 0.15 11.8 0.0 1 9.1 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KEG15122.1 - 0.15 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KEG15122.1 - 0.19 10.9 0.0 0.47 9.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RRM_1 PF00076.22 KEG15123.1 - 1e-12 47.7 0.0 7.4e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuclease_3 PF00636.26 KEG15124.1 - 0.026 15.2 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease III domain Shisa PF13908.6 KEG15125.1 - 0.00054 20.3 1.6 0.0035 17.6 0.1 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF1180 PF06679.12 KEG15125.1 - 0.0044 17.5 1.2 0.017 15.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 KEG15125.1 - 0.0053 17.6 0.3 0.013 16.3 0.3 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 KEG15125.1 - 0.0088 16.0 2.4 0.021 14.7 2.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Trp_oprn_chp PF09534.10 KEG15125.1 - 0.014 15.2 0.1 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SP_C-Propep PF08999.10 KEG15125.1 - 0.015 15.1 3.1 0.035 13.9 3.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Ly49 PF08391.10 KEG15125.1 - 0.032 14.6 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Orf78 PF06024.12 KEG15125.1 - 0.042 14.2 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) NPDC1 PF06809.11 KEG15125.1 - 0.047 12.7 1.6 0.96 8.4 0.0 2.1 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) ECSCR PF15820.5 KEG15125.1 - 0.056 13.3 1.2 0.12 12.2 1.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator AJAP1_PANP_C PF15298.6 KEG15125.1 - 0.079 13.2 7.2 6.1 7.0 0.0 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus LRR19-TM PF15176.6 KEG15125.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DAG1 PF05454.11 KEG15125.1 - 0.09 12.1 3.0 0.091 12.1 1.8 1.6 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 KEG15125.1 - 0.096 12.6 0.1 0.096 12.6 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF2644 PF10841.8 KEG15125.1 - 0.19 12.0 1.1 0.34 11.2 0.3 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2644) Baculo_11_kDa PF06143.11 KEG15125.1 - 0.29 10.7 6.9 0.06 12.9 3.4 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family HHV-5_US34A PF17087.5 KEG15125.1 - 0.32 11.2 4.7 0.61 10.3 4.7 1.4 1 0 0 1 1 1 0 Herpesvirus US34A protein family TMEM52 PF14979.6 KEG15125.1 - 2 8.3 5.5 5.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Transmembrane 52 DUF2771 PF10969.8 KEG15125.1 - 2.1 8.4 7.6 6.6 6.8 3.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2771) TSNAXIP1_N PF15739.5 KEG15126.1 - 4.9e-14 52.6 1.0 4.9e-14 52.6 1.0 3.0 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus FliJ PF02050.16 KEG15126.1 - 0.05 13.8 9.8 0.14 12.4 8.6 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein CENP-H PF05837.12 KEG15126.1 - 0.29 11.5 12.5 0.14 12.6 8.9 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF2353 PF09789.9 KEG15126.1 - 0.51 9.7 12.7 0.031 13.6 4.1 2.5 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spc42p PF11544.8 KEG15126.1 - 0.88 9.6 2.9 14 5.7 0.6 2.7 2 0 0 2 2 2 0 Spindle pole body component Spc42p Csm1_N PF18504.1 KEG15126.1 - 2.6 8.5 8.2 19 5.7 0.1 3.3 2 1 2 4 4 4 0 Csm1 N-terminal domain DUF4407 PF14362.6 KEG15126.1 - 5.8 6.2 9.5 8.6 5.6 8.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TEX13 PF15186.6 KEG15126.1 - 6.2 6.5 12.9 12 5.6 0.1 3.1 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family TIP120 PF08623.10 KEG15128.1 - 3.2e-13 49.8 0.0 6.5e-11 42.3 0.0 3.5 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) Chalcone PF02431.15 KEG15128.1 - 0.015 14.8 0.1 6 6.2 0.0 2.7 2 0 0 2 2 2 0 Chalcone-flavanone isomerase DUF3385 PF11865.8 KEG15128.1 - 0.12 12.3 1.3 0.75 9.7 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Iso_dh PF00180.20 KEG15129.1 - 5.8e-77 259.2 0.0 6.8e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TPR_12 PF13424.6 KEG15130.1 - 2.4e-14 53.4 42.8 0.0012 19.1 0.1 8.7 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEG15130.1 - 2.4e-11 43.4 37.0 0.0024 18.5 0.3 13.1 9 4 4 13 13 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEG15130.1 - 8.7e-08 31.7 17.7 0.22 11.6 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEG15130.1 - 3.5e-05 24.2 31.2 0.0078 16.7 3.3 9.0 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEG15130.1 - 0.00023 21.3 1.3 5.6 7.6 0.1 4.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG15130.1 - 0.0023 17.9 32.6 2.6 8.4 0.0 11.7 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEG15130.1 - 0.0082 16.3 8.5 0.72 10.2 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEG15130.1 - 0.17 12.6 19.2 12 6.8 0.0 9.0 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG15130.1 - 7.7 6.5 21.9 50 3.9 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 KEG15131.1 - 1.4e-45 155.4 0.3 1.6e-45 155.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WW PF00397.26 KEG15132.1 - 9.1e-05 22.5 0.1 0.00019 21.5 0.1 1.6 1 0 0 1 1 1 1 WW domain Ribosomal_L23 PF00276.20 KEG15133.1 - 9.6e-06 25.9 0.2 1.4e-05 25.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 DUF5095 PF17016.5 KEG15133.1 - 0.024 14.3 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) LRR_8 PF13855.6 KEG15134.1 - 2e-17 62.7 10.8 1.3e-16 60.0 1.9 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KEG15134.1 - 3.8e-11 43.0 6.4 7.4e-06 26.2 0.5 3.7 1 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG15134.1 - 4.6e-05 23.0 0.3 0.00038 20.0 0.1 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 KEG15134.1 - 0.26 12.0 6.6 6.9 7.6 1.5 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 KEG15134.1 - 0.34 11.1 5.2 4.6 7.6 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Kdo PF06293.14 KEG15135.1 - 2.1e-08 33.8 0.2 3.7e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEG15135.1 - 2.5e-08 33.7 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KEG15135.1 - 2.7e-06 27.0 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KEG15135.1 - 0.00026 21.0 1.9 0.0049 16.8 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KEG15135.1 - 0.02 14.2 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Phytochelatin PF05023.14 KEG15136.1 - 8.3e-08 31.7 0.0 0.11 11.7 0.0 4.2 4 0 0 4 4 4 4 Phytochelatin synthase Acetyltransf_1 PF00583.25 KEG15137.1 - 0.00058 20.1 0.1 0.0061 16.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEG15137.1 - 0.0037 17.7 0.0 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CRAM_rpt PF07016.11 KEG15137.1 - 0.052 13.3 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor Acetyltransf_10 PF13673.7 KEG15137.1 - 0.2 11.6 0.1 0.55 10.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KEG15138.1 - 2.1e-27 94.8 2.2 2.5e-09 36.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EIIA-man PF03610.16 KEG15138.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component Myb_DNA-binding PF00249.31 KEG15139.1 - 5.5e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEG15139.1 - 0.0001 22.5 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MCRS_N PF13325.6 KEG15139.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein PIH1 PF08190.12 KEG15140.1 - 4.1e-20 71.9 0.7 2.7e-08 33.4 0.3 3.4 1 1 1 2 2 2 2 PIH1 N-terminal domain PIH1_CS PF18201.1 KEG15140.1 - 1.8e-10 41.1 0.0 4.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain Beta_helix PF13229.6 KEG15141.1 - 0.00023 21.1 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Right handed beta helix region GDA1_CD39 PF01150.17 KEG15141.1 - 0.13 10.9 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family SET PF00856.28 KEG15142.1 - 5.7e-07 30.1 0.0 1.3e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 SET domain tRNA-synt_2c PF01411.19 KEG15142.1 - 0.29 9.6 0.0 0.41 9.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) UQ_con PF00179.26 KEG15143.1 - 0.0008 19.1 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme T6PP_N PF18572.1 KEG15143.1 - 0.068 13.0 0.6 0.21 11.4 0.6 1.9 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain ProRS-C_1 PF09180.11 KEG15144.1 - 1.8e-26 92.1 1.2 8.3e-26 90.0 1.2 2.2 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 KEG15144.1 - 3.3e-25 88.6 0.1 6.4e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 KEG15144.1 - 2.3e-15 56.5 0.0 6.7e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEG15144.1 - 5e-15 55.9 0.0 9.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) CortBP2 PF09727.9 KEG15144.1 - 1.5 8.7 4.6 1.2 9.0 1.6 2.0 2 0 0 2 2 2 0 Cortactin-binding protein-2 Complex1_LYR PF05347.15 KEG15145.1 - 1.8e-12 47.1 1.2 1.8e-12 47.1 1.2 1.9 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEG15145.1 - 0.0011 19.6 0.3 0.002 18.8 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KEG15145.1 - 0.046 14.3 0.5 0.046 14.3 0.5 2.1 2 1 1 3 3 3 0 Complex1_LYR-like DUF3629 PF12302.8 KEG15145.1 - 0.066 12.7 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Spidroin_N PF16763.5 KEG15147.1 - 0.2 11.7 3.1 0.59 10.2 3.1 1.7 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Cmc1 PF08583.10 KEG15148.1 - 0.00074 19.5 0.8 0.0013 18.7 0.8 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CBP_GIL PF10995.8 KEG15148.1 - 0.077 11.7 1.3 0.12 11.0 1.3 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis GIL zf-C3HC4_3 PF13920.6 KEG15150.1 - 1.5e-14 53.6 11.0 2.5e-14 52.8 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEG15150.1 - 1.1e-06 28.4 11.3 2.1e-06 27.5 11.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEG15150.1 - 1.8e-06 28.2 12.6 3.5e-06 27.3 12.6 1.5 1 0 0 1 1 1 1 Ring finger domain Spt20 PF12090.8 KEG15150.1 - 0.00015 21.4 24.0 0.00026 20.7 24.0 1.4 1 0 0 1 1 1 1 Spt20 family zf-C3HC4_2 PF13923.6 KEG15150.1 - 0.00044 20.0 15.8 0.00077 19.2 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SprA-related PF12118.8 KEG15150.1 - 0.018 14.2 16.5 0.038 13.1 16.5 1.5 1 0 0 1 1 1 0 SprA-related family zf-RING_5 PF14634.6 KEG15150.1 - 0.035 14.1 11.7 0.075 13.0 11.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Pox_Ag35 PF03286.14 KEG15150.1 - 0.095 12.5 3.3 0.18 11.6 3.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pex14_N PF04695.13 KEG15150.1 - 0.39 11.4 19.3 0.81 10.3 19.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NPR3 PF03666.13 KEG15150.1 - 0.41 9.4 6.8 1.9 7.2 7.3 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Suf PF05843.14 KEG15150.1 - 0.45 10.4 15.9 0.84 9.6 15.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-P11 PF03854.14 KEG15150.1 - 0.6 9.8 8.8 1.5 8.6 8.8 1.7 1 1 0 1 1 1 0 P-11 zinc finger Presenilin PF01080.17 KEG15150.1 - 0.79 8.4 12.8 1 8.0 12.8 1.2 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 KEG15150.1 - 0.84 9.7 8.6 0.45 10.5 6.5 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Gti1_Pac2 PF09729.9 KEG15150.1 - 0.87 9.7 7.5 1.9 8.5 7.5 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family HABP4_PAI-RBP1 PF04774.15 KEG15150.1 - 1 10.2 12.4 15 6.4 0.0 2.4 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family PAT1 PF09770.9 KEG15150.1 - 1.7 6.8 20.1 2.1 6.5 20.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 KEG15150.1 - 2.2 7.2 14.2 3 6.7 14.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-RING_10 PF16685.5 KEG15150.1 - 2.2 8.5 10.2 4.8 7.4 10.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ndc1_Nup PF09531.10 KEG15150.1 - 5.1 5.7 7.8 5.6 5.5 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Activator_LAG-3 PF11498.8 KEG15150.1 - 5.5 5.8 34.8 8.1 5.3 34.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RR_TM4-6 PF06459.12 KEG15150.1 - 5.7 6.7 9.8 11 5.8 9.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 API5 PF05918.11 KEG15150.1 - 7.8 5.2 14.3 11 4.7 14.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SUIM_assoc PF16619.5 KEG15151.1 - 0.012 15.7 5.5 0.012 15.7 5.5 7.2 7 2 0 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 LHH PF14411.6 KEG15151.1 - 7 6.9 8.7 0.73 10.1 0.5 3.6 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Ras PF00071.22 KEG15152.1 - 3.2e-53 179.7 0.0 3.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG15152.1 - 5e-32 110.6 0.0 6.5e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG15152.1 - 1e-09 38.1 0.0 1.7e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEG15152.1 - 0.00055 19.4 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEG15152.1 - 0.031 14.3 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KEG15152.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KEG15152.1 - 0.044 13.7 0.0 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KEG15152.1 - 0.12 12.7 0.2 0.19 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain zf-AN1 PF01428.16 KEG15153.1 - 1.3e-16 60.5 25.3 1e-08 35.2 6.6 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KEG15153.1 - 0.00012 22.3 15.8 0.034 14.5 5.6 2.6 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Methyltr_RsmB-F PF01189.17 KEG15154.1 - 3.6e-35 121.4 0.0 1.4e-34 119.5 0.0 2.0 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KEG15154.1 - 0.0005 20.2 0.0 0.00089 19.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ank_4 PF13637.6 KEG15155.1 - 1.5e-20 73.3 0.4 2.3e-07 31.2 0.0 4.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG15155.1 - 2.3e-20 73.0 0.2 1.8e-08 34.8 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEG15155.1 - 1.3e-19 68.2 0.7 0.00043 20.5 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KEG15155.1 - 7e-18 64.5 2.8 1.2e-08 35.0 0.0 4.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KEG15155.1 - 6.3e-14 51.7 0.6 0.021 15.3 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Nitr_red_bet_C PF14711.6 KEG15155.1 - 0.11 12.2 0.1 9.6 6.0 0.0 2.7 3 0 0 3 3 3 0 Respiratory nitrate reductase beta C-terminal PDEase_I PF00233.19 KEG15156.1 - 3.9e-78 262.5 0.9 7.1e-78 261.6 0.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Chalcone_3 PF16036.5 KEG15156.1 - 0.042 14.0 0.5 0.087 12.9 0.5 1.5 1 0 0 1 1 1 0 Chalcone isomerase-like Pkinase PF00069.25 KEG15157.1 - 2.3e-72 243.5 0.0 2.7e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15157.1 - 1.2e-36 126.3 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEG15157.1 - 4.1e-05 23.1 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG15157.1 - 0.06 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Vps16_N PF04841.13 KEG15158.1 - 7.8e-41 140.2 0.0 1.8e-40 139.0 0.0 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KEG15158.1 - 1.3e-31 109.9 1.2 1.1e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Peptidase_C2 PF00648.21 KEG15159.1 - 9.8e-20 70.8 0.0 3.9e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 KEG15159.1 - 0.0027 18.0 0.1 0.034 14.4 0.0 2.3 2 0 0 2 2 2 1 Calpain large subunit, domain III TMCO5 PF14992.6 KEG15160.1 - 0.09 12.3 15.8 0.14 11.7 15.8 1.3 1 0 0 1 1 1 0 TMCO5 family Baculo_PEP_C PF04513.12 KEG15160.1 - 0.15 12.1 3.8 0.38 10.8 1.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gp58 PF07902.11 KEG15160.1 - 0.16 10.2 5.2 0.25 9.6 5.2 1.3 1 0 0 1 1 1 0 gp58-like protein Fib_alpha PF08702.10 KEG15160.1 - 0.27 11.4 18.2 0.4 10.8 9.8 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2852 PF11014.8 KEG15160.1 - 0.42 10.8 10.2 3.6 7.8 3.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) CENP-K PF11802.8 KEG15160.1 - 0.72 9.4 16.3 0.89 9.1 15.7 1.5 1 1 0 1 1 1 0 Centromere-associated protein K PKcGMP_CC PF16808.5 KEG15160.1 - 2.6 8.0 14.9 6 6.8 1.5 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bacillus_HBL PF05791.11 KEG15160.1 - 2.8 7.7 8.7 8.5 6.2 3.8 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MSL1_dimer PF16801.5 KEG15160.1 - 2.9 7.7 8.2 0.96 9.3 0.3 3.2 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 LMBR1 PF04791.16 KEG15160.1 - 3 6.6 7.4 4.1 6.2 7.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 KEG15160.1 - 3.1 7.0 15.2 1.4 8.1 0.7 2.6 1 1 1 2 2 2 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 KEG15160.1 - 3.5 8.3 34.7 0.14 12.8 4.4 4.2 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Myosin_TH1 PF06017.13 KEG15161.1 - 0.081 12.6 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding WD40 PF00400.32 KEG15162.1 - 2.3e-12 47.2 8.8 0.0032 18.2 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG15162.1 - 3.1e-08 33.8 0.2 0.0025 18.1 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PPR_2 PF13041.6 KEG15163.1 - 8.5e-07 29.1 0.0 0.018 15.2 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KEG15163.1 - 8.1e-05 22.6 0.0 1.9 8.6 0.0 4.1 3 2 2 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 KEG15163.1 - 0.0013 18.8 0.1 17 5.9 0.0 4.8 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 KEG15163.1 - 0.0015 17.9 0.4 0.0015 17.9 0.4 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP HR1 PF02185.16 KEG15163.1 - 0.082 13.0 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Hr1 repeat Laminin_I PF06008.14 KEG15163.1 - 0.095 12.4 3.8 0.55 9.9 3.8 2.0 1 1 0 1 1 1 0 Laminin Domain I TPR_12 PF13424.6 KEG15163.1 - 0.3 11.4 5.9 34 4.8 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2688 PF10892.8 KEG15163.1 - 4.4 6.8 5.2 0.53 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Glyco_trans_1_4 PF13692.6 KEG15164.1 - 0.00027 21.4 0.0 0.0015 19.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pro_isomerase PF00160.21 KEG15165.1 - 6e-38 130.6 0.1 1.6e-37 129.2 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CDC45 PF02724.14 KEG15166.1 - 0.058 11.7 0.4 0.077 11.3 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FANCI_HD2 PF14680.6 KEG15167.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 Roc PF08477.13 KEG15168.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEG15168.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEG15168.1 - 0.16 12.0 0.1 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 Dynamin family Metallophos PF00149.28 KEG15169.1 - 1.8e-13 51.5 2.1 4.3e-13 50.2 1.6 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEG15169.1 - 1.7e-06 28.3 0.0 6.9e-06 26.4 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain 14-3-3 PF00244.20 KEG15171.1 - 0.00011 21.8 1.2 0.29 10.6 0.0 2.7 3 0 0 3 3 3 2 14-3-3 protein RNA12 PF10443.9 KEG15171.1 - 0.057 12.1 0.3 0.09 11.5 0.3 1.2 1 0 0 1 1 1 0 RNA12 protein GBP_C PF02841.14 KEG15171.1 - 0.26 10.7 1.0 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain WD40 PF00400.32 KEG15172.1 - 5.1e-23 80.9 18.8 6.7e-06 26.8 0.1 11.4 13 0 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG15172.1 - 3.2e-13 49.8 0.0 0.06 13.7 0.0 7.7 5 3 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KEG15172.1 - 1.2e-10 41.6 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PD40 PF07676.12 KEG15172.1 - 0.075 13.0 1.4 14 5.7 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat EPF PF17181.4 KEG15172.1 - 0.12 12.4 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Epidermal patterning factor proteins Ge1_WD40 PF16529.5 KEG15172.1 - 0.14 11.1 0.8 8.9 5.2 0.0 3.6 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cnd1 PF12717.7 KEG15173.1 - 1.6e-06 28.3 5.7 0.0018 18.3 0.1 5.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEG15173.1 - 0.0029 18.2 4.7 0.57 10.8 0.0 5.8 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 KEG15173.1 - 0.018 14.1 0.1 0.26 10.3 0.0 2.8 3 0 0 3 3 3 0 Dopey, N-terminal Proteasom_PSMB PF10508.9 KEG15173.1 - 0.019 13.5 2.9 8.8 4.7 0.0 3.7 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KEG15173.1 - 0.022 15.3 13.4 0.71 10.5 0.0 7.2 7 0 0 7 7 7 0 HEAT-like repeat RIX1 PF08167.12 KEG15173.1 - 0.087 12.6 3.3 2.7 7.7 0.1 4.5 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis TPR_6 PF13174.6 KEG15173.1 - 0.11 13.1 1.9 2e+02 3.0 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NopRA1 PF16201.5 KEG15173.1 - 0.19 11.3 2.8 1 8.9 0.0 3.5 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 CDP-OH_P_transf PF01066.21 KEG15174.1 - 2.1e-17 63.6 0.6 2.1e-17 63.6 0.6 3.5 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_S8 PF00410.19 KEG15175.1 - 1.1e-08 35.0 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 RNA_pol_Rpb5_C PF01191.19 KEG15176.1 - 4.9e-22 77.6 0.0 1.1e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KEG15176.1 - 3.4e-05 24.3 0.1 0.00089 19.8 0.1 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 KEG15177.1 - 4.9e-27 93.6 0.1 7.9e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KEG15177.1 - 7.6e-18 64.9 0.8 7.6e-18 64.9 0.8 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain PDZ_6 PF17820.1 KEG15178.1 - 0.00024 20.9 1.6 0.00029 20.6 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KEG15178.1 - 0.017 15.4 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain LysM PF01476.20 KEG15178.1 - 0.18 11.9 0.0 0.81 9.8 0.0 2.0 2 0 0 2 2 2 0 LysM domain zf-C2H2_jaz PF12171.8 KEG15179.1 - 0.00014 22.0 2.0 0.0002 21.6 2.0 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KEG15179.1 - 0.0097 15.7 1.0 0.015 15.1 1.0 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 KEG15179.1 - 0.031 14.7 2.7 0.046 14.1 2.7 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Syntaxin-6_N PF09177.11 KEG15180.1 - 0.063 13.8 0.9 1.2 9.7 1.1 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Phage_GPO PF05929.11 KEG15180.1 - 8.5 5.9 11.1 0.29 10.7 0.2 2.7 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-CCHC_2 PF13696.6 KEG15181.1 - 7.5e-10 38.4 5.9 1.3e-09 37.7 5.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KEG15181.1 - 0.018 15.1 3.8 0.048 13.8 3.8 1.8 1 0 0 1 1 1 0 Zinc knuckle DWNN PF08783.11 KEG15181.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 DWNN domain Herpes_UL46 PF03387.14 KEG15181.1 - 0.032 13.0 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein zf-CCHC_3 PF13917.6 KEG15181.1 - 0.058 13.4 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Zn-ribbon_8 PF09723.10 KEG15181.1 - 1.3 9.2 5.5 14 5.9 0.9 2.7 2 0 0 2 2 2 0 Zinc ribbon domain NDUFA12 PF05071.16 KEG15182.1 - 1.2e-06 29.3 0.3 3e-06 28.0 0.3 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ICMT PF04140.14 KEG15183.1 - 8.3e-21 74.2 1.7 8.3e-21 74.2 1.7 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KEG15183.1 - 9e-05 22.8 2.2 9e-05 22.8 2.2 2.7 2 2 0 2 2 2 1 Phospholipid methyltransferase TMEM238 PF15125.6 KEG15183.1 - 1.3 9.2 8.0 0.84 9.9 0.6 2.6 2 0 0 2 2 2 0 TMEM238 protein family PAF-AH_p_II PF03403.13 KEG15184.1 - 3.6e-13 48.8 0.0 1.6e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KEG15184.1 - 0.029 13.6 0.6 4.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEG15184.1 - 0.033 14.8 1.6 0.056 14.0 1.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 KEG15185.1 - 3.4e-26 91.6 0.0 7e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KEG15185.1 - 2.4e-11 43.1 0.0 3.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KEG15185.1 - 0.0001 23.0 0.2 0.0001 23.0 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KEG15185.1 - 0.00028 20.0 0.0 0.019 14.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Thioesterase PF00975.20 KEG15185.1 - 0.0032 17.6 0.0 0.0051 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KEG15185.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 KEG15185.1 - 0.057 12.7 1.4 3.4 6.9 0.1 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Glyoxalase PF00903.25 KEG15186.1 - 9.7e-15 54.9 0.1 1.4e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEG15186.1 - 1.6e-09 38.0 0.0 2.7e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEG15186.1 - 0.0015 19.3 0.0 0.0023 18.7 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KEG15186.1 - 0.0092 15.9 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 KEG15186.1 - 0.041 14.0 0.0 0.046 13.8 0.0 1.2 1 1 0 1 1 1 0 CppA N-terminal DNA_pol_A_exo1 PF01612.20 KEG15188.1 - 5e-14 52.4 0.0 7.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC PF00098.23 KEG15188.1 - 9.5e-08 31.8 31.3 0.0012 18.8 2.1 4.6 4 0 0 4 4 4 3 Zinc knuckle zf-C2H2_10 PF16588.5 KEG15188.1 - 0.0022 17.7 36.1 0.0032 17.2 4.5 4.4 4 0 0 4 4 4 3 C2H2 zinc-finger DnaJ_C PF01556.18 KEG15189.1 - 1.5e-33 116.0 0.0 2.1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEG15189.1 - 9.3e-21 73.7 0.3 1.9e-20 72.7 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEG15189.1 - 4.8e-14 52.5 18.3 9.2e-14 51.6 18.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KEG15189.1 - 0.022 14.8 5.8 0.49 10.4 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KEG15189.1 - 0.081 12.9 14.1 0.055 13.4 4.3 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein NRDD PF13597.6 KEG15189.1 - 1.9 7.1 4.2 0.98 8.1 2.3 1.4 1 1 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Lar_restr_allev PF14354.6 KEG15189.1 - 6.1 7.3 9.4 4 7.9 2.2 3.4 1 1 2 3 3 3 0 Restriction alleviation protein Lar Galactosyl_T PF01762.21 KEG15190.1 - 1.5e-05 24.9 0.1 0.00056 19.8 0.1 2.8 3 1 0 3 3 3 1 Galactosyltransferase Zeta_toxin PF06414.12 KEG15191.1 - 3e-06 26.7 0.1 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 KEG15191.1 - 0.023 14.9 0.0 0.062 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEG15191.1 - 0.025 14.8 0.6 0.79 9.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 KEG15191.1 - 0.033 13.9 0.4 0.068 12.9 0.1 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KEG15191.1 - 0.039 14.5 0.1 0.15 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEG15191.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_2 PF07719.17 KEG15192.1 - 0.0023 17.9 0.1 2.4 8.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG15192.1 - 0.036 13.9 0.1 2.5 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEG15192.1 - 0.072 13.4 0.5 1.2 9.5 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DENN PF02141.21 KEG15193.1 - 1e-23 84.2 1.1 1.8e-23 83.5 1.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KEG15193.1 - 0.00012 22.8 0.2 0.00012 22.8 0.2 1.9 2 0 0 2 2 2 1 uDENN domain PPR PF01535.20 KEG15194.1 - 6e-24 82.6 35.5 0.013 15.7 0.2 14.4 17 0 0 17 17 17 7 PPR repeat PPR_2 PF13041.6 KEG15194.1 - 1.6e-21 76.2 25.2 6.9e-05 23.0 0.3 11.9 8 3 6 14 14 14 7 PPR repeat family PPR_3 PF13812.6 KEG15194.1 - 1.7e-17 63.2 4.0 0.0046 17.0 0.0 8.4 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KEG15194.1 - 1.2e-09 37.8 11.3 0.00013 21.5 0.2 6.2 3 2 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KEG15194.1 - 1.7e-09 37.2 2.8 0.011 15.5 0.0 5.9 6 0 0 6 6 6 2 PPR repeat TPR_19 PF14559.6 KEG15194.1 - 5.7e-05 23.5 3.4 0.0014 19.1 2.7 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_MA_2 PF13485.6 KEG15194.1 - 0.1 12.3 0.2 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Peptidase MA superfamily DUF4004 PF13171.6 KEG15194.1 - 0.11 12.7 0.4 0.62 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) FANCI_S3 PF14677.6 KEG15194.1 - 0.58 9.8 5.3 5.2 6.7 0.1 3.3 4 0 0 4 4 4 0 FANCI solenoid 3 Cupin_8 PF13621.6 KEG15195.1 - 2.7e-46 158.4 0.1 4.4e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KEG15195.1 - 1.5e-26 93.5 0.0 4.8e-26 91.9 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 KEG15195.1 - 4e-09 36.2 0.2 0.00028 20.8 0.0 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 KEG15195.1 - 4.8e-09 36.3 3.3 0.43 10.9 0.3 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Cupin_4 PF08007.12 KEG15195.1 - 3.8e-08 33.2 0.0 9.3e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_4 PF13418.6 KEG15195.1 - 0.003 17.5 14.7 0.028 14.4 0.3 5.9 5 2 1 6 6 6 1 Galactose oxidase, central domain JmjC PF02373.22 KEG15195.1 - 0.085 13.3 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase MTS PF05175.14 KEG15195.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ZapB PF06005.12 KEG15197.1 - 0.12 12.8 13.4 1.1 9.8 3.3 3.5 2 1 1 3 3 3 0 Cell division protein ZapB FapA PF03961.13 KEG15197.1 - 0.2 10.2 2.1 0.35 9.4 2.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5446 PF17522.2 KEG15197.1 - 0.76 10.0 7.4 0.12 12.5 2.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) PARG_cat PF05028.14 KEG15198.1 - 1.6e-98 330.2 0.0 2e-98 329.8 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Tctex-1 PF03645.13 KEG15199.1 - 6.6e-24 84.1 0.0 8.4e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family SpoU_methylase PF00588.19 KEG15201.1 - 3.7e-08 33.6 0.0 8.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Sybindin PF04099.12 KEG15202.1 - 2.7e-18 66.3 0.0 3e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family GerD PF17898.1 KEG15202.1 - 0.0085 16.0 0.0 0.034 14.1 0.0 2.0 1 1 0 1 1 1 1 Spore germination GerD central core domain RIF5_SNase_1 PF18187.1 KEG15202.1 - 0.028 14.1 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 TbRIF5 SNase domain 1 CHU_C PF13585.6 KEG15202.1 - 0.098 12.7 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Pkinase PF00069.25 KEG15203.1 - 6.9e-45 153.5 0.0 1.5e-44 152.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15203.1 - 3.1e-26 92.2 0.0 1.3e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEG15203.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEG15203.1 - 3.9e-05 22.6 0.0 5.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEG15203.1 - 0.048 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CAP_N PF01213.19 KEG15203.1 - 0.17 11.4 0.3 0.43 10.0 0.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Alb1 PF09135.11 KEG15204.1 - 0.00072 20.4 12.3 0.00072 20.4 12.3 2.0 1 1 1 2 2 2 1 Alb1 Leo1 PF04004.13 KEG15205.1 - 2.7e-15 56.6 0.4 2.7e-15 56.6 0.4 2.1 2 1 0 2 2 2 1 Leo1-like protein Nucleo_P87 PF07267.11 KEG15205.1 - 0.43 9.4 9.3 0.64 8.8 9.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CNDH2_C PF16858.5 KEG15205.1 - 0.49 10.2 10.8 0.83 9.5 10.8 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop53 PF07767.11 KEG15205.1 - 7 5.9 17.3 17 4.7 17.3 1.7 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Aminotran_5 PF00266.19 KEG15206.1 - 2.1e-48 165.1 0.0 2.6e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEG15206.1 - 0.0021 17.4 0.0 0.0053 16.1 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Pullulanase_Ins PF18494.1 KEG15207.1 - 0.17 12.4 0.0 0.51 10.9 0.0 1.8 1 0 0 1 1 1 0 Pullulanase Ins domain MFS_1 PF07690.16 KEG15208.1 - 1.1e-28 100.2 42.5 1.1e-26 93.7 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEG15208.1 - 1.3e-07 30.9 16.4 9.9e-06 24.7 5.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KEG15208.1 - 1.3e-05 24.3 11.2 0.0028 16.6 0.0 3.3 2 2 1 3 3 3 2 MFS_1 like family MFS_1 PF07690.16 KEG15209.1 - 1.5e-23 83.3 26.9 1.5e-23 83.3 26.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEG15209.1 - 3e-10 39.5 7.5 2.6e-06 26.6 1.4 2.6 2 1 1 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 KEG15209.1 - 7.9e-07 28.3 5.6 7.9e-07 28.3 5.6 3.1 2 2 2 4 4 4 1 Sugar (and other) transporter MFS_4 PF06779.14 KEG15209.1 - 2.3e-05 23.9 0.7 2.3e-05 23.9 0.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KEG15209.1 - 0.00017 20.2 0.1 0.00028 19.4 0.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector BT1 PF03092.16 KEG15209.1 - 0.0031 15.8 3.2 0.049 11.8 0.0 2.8 2 1 1 3 3 3 2 BT1 family Adeno_E1B_55K_N PF04623.12 KEG15209.1 - 0.041 14.6 0.1 0.094 13.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Hydrolase_4 PF12146.8 KEG15210.1 - 1.5e-07 31.0 0.0 2.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF818 PF05677.12 KEG15210.1 - 1.1e-05 24.6 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 KEG15210.1 - 0.00022 21.9 0.9 0.0004 21.1 0.4 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEG15210.1 - 0.028 14.3 0.1 0.061 13.2 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEG15210.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEG15210.1 - 0.037 13.7 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SUIM_assoc PF16619.5 KEG15211.1 - 0.0019 18.2 0.5 0.0066 16.5 0.5 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 IQ PF00612.27 KEG15211.1 - 0.0024 17.5 2.7 0.0083 15.8 2.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dpy-30 PF05186.13 KEG15211.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif Rrn6 PF10214.9 KEG15212.1 - 0.018 13.6 0.1 0.018 13.6 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NERD PF08378.11 KEG15215.1 - 1e-13 51.7 0.2 1.8e-12 47.7 0.0 2.4 2 1 0 2 2 2 1 Nuclease-related domain UPF0102 PF02021.17 KEG15215.1 - 6.9e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 Mrr_cat PF04471.12 KEG15215.1 - 0.17 11.9 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease tRNA-synt_1 PF00133.22 KEG15216.1 - 9e-218 724.4 2.9 1e-217 724.2 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEG15216.1 - 9.7e-27 93.8 0.1 2.8e-26 92.3 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KEG15216.1 - 1.8e-13 50.0 1.5 1.3e-05 24.1 0.2 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KEG15216.1 - 0.021 14.2 0.2 0.16 11.3 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Phyto_Pns9_10 PF05878.11 KEG15216.1 - 0.11 11.6 0.1 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 PRA1 PF03208.19 KEG15217.1 - 2e-08 34.0 5.1 3.3e-08 33.3 5.1 1.3 1 0 0 1 1 1 1 PRA1 family protein SWIM PF04434.17 KEG15218.1 - 0.08 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.23 KEG15219.1 - 0.0048 16.6 0.0 0.018 14.8 0.0 2.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Neur_chan_memb PF02932.16 KEG15219.1 - 1.4 8.9 6.7 2.1 8.3 6.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DAO PF01266.24 KEG15221.1 - 1.7e-20 73.9 3.6 7.1e-20 71.9 1.3 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEG15221.1 - 1.2e-07 31.8 0.2 4e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEG15221.1 - 0.00011 21.5 0.2 0.00025 20.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEG15221.1 - 0.00033 19.9 0.2 0.00069 18.8 0.2 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KEG15221.1 - 0.00058 20.4 1.3 0.0015 19.0 0.8 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEG15221.1 - 0.0014 17.8 0.6 0.0026 16.9 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_4 PF13439.6 KEG15221.1 - 0.0079 16.2 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pyr_redox_3 PF13738.6 KEG15221.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEG15221.1 - 0.016 13.9 0.2 0.026 13.2 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEG15221.1 - 0.02 14.2 0.2 0.04 13.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KEG15221.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 KEG15221.1 - 0.029 14.3 0.3 0.069 13.0 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEG15221.1 - 0.054 12.8 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KEG15221.1 - 0.085 12.8 0.4 0.23 11.4 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Helicase_C PF00271.31 KEG15222.1 - 6.5e-16 58.7 0.0 1.9e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KEG15222.1 - 9.2e-16 58.0 0.0 2.2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEG15222.1 - 1.8e-15 57.1 0.1 3.5e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KEG15222.1 - 4.1e-08 33.2 0.0 1.5e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEG15222.1 - 0.0006 20.1 0.0 0.0027 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEG15222.1 - 0.0043 16.2 0.0 0.0093 15.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KEG15222.1 - 0.029 14.4 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KEG15222.1 - 0.033 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KEG15222.1 - 0.061 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KEG15222.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KEG15222.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KEG15222.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KEG15222.1 - 0.11 13.0 0.1 0.28 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEG15222.1 - 0.14 11.9 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Metallophos PF00149.28 KEG15223.1 - 5.4e-07 30.3 0.0 8.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCEMA1 PF07418.11 KEG15226.1 - 7 6.1 8.8 11 5.5 8.8 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Cullin_binding PF03556.15 KEG15228.1 - 2.4e-27 95.8 0.9 3.5e-27 95.2 0.9 1.3 1 0 0 1 1 1 1 Cullin binding RNA_Me_trans PF04252.13 KEG15228.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase BT1 PF03092.16 KEG15230.1 - 2.7e-179 596.8 7.5 3.1e-179 596.6 7.5 1.0 1 0 0 1 1 1 1 BT1 family Terpene_synth PF01397.21 KEG15231.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain DUF755 PF05501.11 KEG15232.1 - 0.00059 20.1 24.4 0.00059 20.1 24.4 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF755) SR-25 PF10500.9 KEG15232.1 - 0.0033 17.1 37.1 0.0033 17.1 37.1 3.0 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 KEG15232.1 - 7.4 7.5 21.8 0.23 12.3 10.7 3.1 3 0 0 3 3 3 0 Chorion family 2 TruD PF01142.18 KEG15233.1 - 2.1e-59 201.5 0.0 5.3e-52 177.0 0.0 2.8 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.6 KEG15234.1 - 6.9e-11 42.0 0.1 1.2e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus HPTransfase PF10090.9 KEG15234.1 - 0.097 12.5 0.2 9.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Histidine phosphotransferase C-terminal domain MS_channel PF00924.18 KEG15235.1 - 3e-18 66.1 0.1 3.5e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.13 KEG15236.1 - 1.3e-46 159.1 0.0 1.8e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family NRho PF16733.5 KEG15236.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Rhomboid N-terminal domain LRR_8 PF13855.6 KEG15237.1 - 4.7e-07 29.5 0.3 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KEG15237.1 - 1.9e-05 24.9 0.6 0.049 14.1 0.3 3.0 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG15237.1 - 0.0009 18.8 0.3 0.0067 15.9 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KEG15237.1 - 0.0047 16.9 0.0 0.46 10.7 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeat DUF3490 PF11995.8 KEG15240.1 - 4.8 7.0 14.5 17 5.2 14.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3490) Sec23_trunk PF04811.15 KEG15241.1 - 7.2e-40 137.1 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KEG15241.1 - 2.1e-16 60.4 0.6 3.5e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KEG15241.1 - 9.6e-15 54.4 6.8 9.6e-15 54.4 6.8 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 KEG15241.1 - 2.2e-13 49.9 0.0 5.8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KEG15241.1 - 0.091 12.7 0.5 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Gelsolin repeat DUF4175 PF13779.6 KEG15242.1 - 0.042 11.8 1.2 0.091 10.7 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Tad PF13400.6 KEG15242.1 - 1.1 9.6 4.1 3.7 7.9 0.1 2.9 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like SNF2_N PF00176.23 KEG15243.1 - 2.4e-30 105.5 0.0 4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG15243.1 - 1.3e-15 57.7 0.0 2.4e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEG15243.1 - 1.1e-05 25.5 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEG15243.1 - 0.0048 16.2 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KEG15243.1 - 0.0052 16.5 0.0 0.09 12.4 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KEG15243.1 - 0.0076 16.5 0.0 1.2 9.4 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_34 PF13872.6 KEG15243.1 - 0.059 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SOG2 PF10428.9 KEG15243.1 - 1.6 7.9 32.1 0.0072 15.6 13.7 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein DDHD PF02862.17 KEG15243.1 - 6.8 6.8 14.6 1.1 9.4 5.3 2.3 2 0 0 2 2 2 0 DDHD domain PRAS PF15798.5 KEG15244.1 - 2.1 8.9 6.5 1.7 9.2 0.1 3.2 3 0 0 3 3 3 0 Proline-rich AKT1 substrate 1 zf-RanBP PF00641.18 KEG15245.1 - 7.8e-05 21.9 2.1 0.00016 20.9 2.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Roughex PF06020.11 KEG15245.1 - 0.014 14.6 7.6 0.026 13.6 7.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein RRM_1 PF00076.22 KEG15245.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ZYG-11_interact PF05884.12 KEG15245.1 - 0.27 10.6 2.6 0.46 9.9 2.6 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 Spt20 PF12090.8 KEG15245.1 - 0.42 10.2 13.4 0.91 9.1 13.4 1.6 1 0 0 1 1 1 0 Spt20 family Apt1 PF10351.9 KEG15245.1 - 7.4 5.3 18.6 0.43 9.4 5.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain TFIIA PF03153.13 KEG15245.1 - 9.1 6.1 19.8 0.61 10.0 13.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IPP-2 PF04979.14 KEG15246.1 - 3.2e-17 63.5 6.1 3.2e-17 63.5 6.1 2.0 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) CDC45 PF02724.14 KEG15246.1 - 4.6 5.4 11.2 6.2 5.0 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KEG15246.1 - 4.7 5.3 14.2 4 5.5 14.2 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KEG15246.1 - 5.5 6.3 17.5 8.8 5.6 17.5 1.3 1 0 0 1 1 1 0 SDA1 TPR_2 PF07719.17 KEG15248.1 - 4.8e-12 45.0 13.7 0.002 18.1 0.0 8.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG15248.1 - 1.9e-10 41.1 16.3 0.00052 20.5 0.2 6.0 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEG15248.1 - 3e-09 36.9 1.6 0.01 16.6 0.0 6.3 4 2 4 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG15248.1 - 1.7e-07 31.4 13.4 0.029 14.6 0.4 7.4 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEG15248.1 - 6.7e-06 25.8 7.8 5.9 7.2 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG15248.1 - 1.4e-05 25.6 2.1 0.0068 17.0 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG15248.1 - 5.1e-05 23.4 12.7 0.00046 20.4 4.4 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KEG15248.1 - 0.00033 21.1 1.0 0.056 13.9 0.1 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_8 PF13181.6 KEG15248.1 - 0.00089 19.3 1.8 2.9 8.3 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEG15248.1 - 0.0015 18.3 19.5 0.21 11.5 0.1 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KEG15248.1 - 0.0035 17.3 12.0 0.07 13.2 2.4 4.3 2 2 3 5 5 5 2 Putative TPR-like repeat TPR_6 PF13174.6 KEG15248.1 - 0.0038 17.8 11.0 0.071 13.8 0.0 6.1 8 0 0 8 8 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KEG15248.1 - 0.012 15.3 0.1 0.19 11.4 0.0 3.0 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Bac_luciferase PF00296.20 KEG15248.1 - 0.059 12.8 0.0 3.3 7.1 0.0 2.2 1 1 1 2 2 2 0 Luciferase-like monooxygenase TPR_9 PF13371.6 KEG15248.1 - 0.092 12.9 0.6 0.82 9.9 0.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CC2-LZ PF16516.5 KEG15248.1 - 0.2 12.0 2.9 0.3 11.5 0.3 2.6 3 0 0 3 3 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fis1_TPR_C PF14853.6 KEG15248.1 - 0.23 11.6 15.6 2 8.5 0.0 5.1 4 1 2 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat RNA_pol_A_bac PF01000.26 KEG15249.1 - 4e-22 78.7 0.0 7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEG15249.1 - 2.3e-14 52.6 0.0 3.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 KEG15249.1 - 0.027 14.6 0.6 0.027 14.6 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 KEG15249.1 - 0.066 13.1 1.9 0.099 12.5 0.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 KEG15249.1 - 0.11 13.1 0.9 0.11 13.1 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEG15249.1 - 0.47 10.6 6.8 0.53 10.4 0.7 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain IQ PF00612.27 KEG15250.1 - 0.0035 17.0 10.3 0.0068 16.1 4.0 3.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif PGM1_C PF18105.1 KEG15250.1 - 0.017 14.6 0.0 0.056 13.0 0.0 1.8 1 0 0 1 1 1 0 PGM1 C-terminal domain RPN1_RPN2_N PF17781.1 KEG15251.1 - 9.4e-84 281.4 0.1 1.4e-83 280.9 0.1 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KEG15251.1 - 8.1e-19 67.4 0.2 7.4e-18 64.3 0.1 2.3 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KEG15251.1 - 5.5e-17 61.2 23.1 1e-05 25.7 0.3 9.4 9 0 0 9 9 9 4 Proteasome/cyclosome repeat IFRD PF05004.13 KEG15251.1 - 0.011 14.8 0.7 0.036 13.2 0.0 2.2 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KEG15251.1 - 0.14 12.7 1.5 1 9.9 0.2 3.4 3 0 0 3 3 3 0 HEAT-like repeat VWA PF00092.28 KEG15252.1 - 7e-07 29.7 0.1 1.1e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEG15252.1 - 0.03 15.0 0.0 0.088 13.5 0.0 1.8 1 1 1 2 2 2 0 von Willebrand factor type A domain NYN_YacP PF05991.11 KEG15252.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 YacP-like NYN domain DOCK-C2 PF14429.6 KEG15253.1 - 9.1e-16 58.2 0.0 1.8e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KEG15253.1 - 6.3e-14 51.5 0.0 2.9e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Dock homology region 2 Fibrinogen_BP PF08017.11 KEG15253.1 - 0.057 11.8 32.4 0.088 11.2 32.4 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein WD40 PF00400.32 KEG15254.1 - 1.9e-05 25.3 12.0 1.2 10.1 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG15254.1 - 0.001 19.3 0.0 11 6.4 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 KEG15255.1 - 1e-34 119.5 0.1 1.1e-34 119.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG15255.1 - 4.7e-20 72.0 0.0 6.5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEG15255.1 - 7.9e-09 35.2 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEG15255.1 - 0.00046 20.3 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEG15255.1 - 0.023 14.6 0.0 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KEG15255.1 - 0.059 13.1 0.0 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KEG15255.1 - 0.2 11.7 0.4 3.2 7.8 0.1 2.3 1 1 0 2 2 2 0 Dynamin family Syntaxin_2 PF14523.6 KEG15257.1 - 2.2e-06 28.0 0.8 2.2e-06 28.0 0.8 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KEG15257.1 - 9.2e-05 22.4 0.1 9.2e-05 22.4 0.1 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KEG15257.1 - 0.00072 19.3 0.9 0.00072 19.3 0.9 2.3 2 0 0 2 2 2 1 Syntaxin DUF5394 PF17372.2 KEG15257.1 - 0.0078 15.8 2.8 0.25 10.9 0.1 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5394) Synaptobrevin PF00957.21 KEG15257.1 - 0.012 15.3 3.8 0.059 13.2 1.3 2.9 3 0 0 3 3 3 0 Synaptobrevin Dynactin_p22 PF07426.11 KEG15257.1 - 0.034 14.0 2.2 0.092 12.6 0.3 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 TipE PF16972.5 KEG15257.1 - 0.17 11.0 0.7 0.22 10.7 0.7 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF1664 PF07889.12 KEG15257.1 - 0.22 11.5 5.2 0.19 11.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KEG15257.1 - 3.2 6.6 11.7 0.21 10.4 1.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ISG65-75 PF11727.8 KEG15257.1 - 7.4 5.7 8.2 1.3 8.2 3.2 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein tRNA-synt_1b PF00579.25 KEG15258.1 - 4.9e-22 78.6 0.0 1.9e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_L3 PF00297.22 KEG15261.1 - 3.7e-07 29.5 0.1 6e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L3 SPT16 PF08644.11 KEG15262.1 - 1.8e-26 93.2 0.8 2.9e-26 92.5 0.1 1.8 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KEG15262.1 - 7e-21 74.9 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KEG15262.1 - 1.4e-08 35.0 0.0 5e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like YL1 PF05764.13 KEG15262.1 - 5.8 7.0 22.8 0.11 12.5 15.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 KEG15262.1 - 7.9 5.7 18.5 14 4.9 18.5 1.3 1 0 0 1 1 1 0 BUD22 ECH_1 PF00378.20 KEG15263.1 - 3.3e-35 121.6 0.0 4.2e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEG15263.1 - 5.6e-09 36.0 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 KEG15265.1 - 1.8e-58 198.0 0.0 3e-56 190.7 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15265.1 - 1.9e-41 142.1 0.0 9.1e-41 139.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG15265.1 - 1.1e-05 24.4 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEG15265.1 - 7.7e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEG15265.1 - 0.00073 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KEG15265.1 - 0.029 14.0 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TPR_14 PF13428.6 KEG15265.1 - 0.14 13.1 0.2 1.6 9.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Bacillus_PapR PF05968.11 KEG15266.1 - 0.11 12.4 0.7 0.17 11.8 0.7 1.2 1 0 0 1 1 1 0 Bacillus PapR protein APH PF01636.23 KEG15268.1 - 6.7e-09 36.0 0.7 2e-08 34.4 0.7 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family ChpXY PF10216.9 KEG15268.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) CENP-F_leu_zip PF10473.9 KEG15269.1 - 0.044 13.8 0.5 0.073 13.1 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2040 PF09745.9 KEG15270.1 - 0.038 14.0 0.2 0.038 14.0 0.2 2.7 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 55 (DUF2040) zf-MYND PF01753.18 KEG15271.1 - 8.6e-06 25.8 6.7 8.6e-06 25.8 6.7 2.8 3 0 0 3 3 3 1 MYND finger SET PF00856.28 KEG15271.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.7 1 1 0 1 1 1 0 SET domain Toxin_34 PF08396.10 KEG15271.1 - 5.3 7.9 11.4 0.4 11.5 1.6 2.8 3 0 0 3 3 3 0 Spider toxin omega agatoxin/Tx1 family WD40 PF00400.32 KEG15274.1 - 2.5e-10 40.8 2.1 0.018 15.9 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_L6e PF01159.19 KEG15275.1 - 4.5e-29 101.2 0.2 4.5e-29 101.2 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.29 KEG15275.1 - 0.0058 16.5 0.0 0.054 13.5 0.0 2.5 3 0 0 3 3 3 1 KOW motif ParE-like_toxin PF15781.5 KEG15275.1 - 0.91 9.5 3.4 0.59 10.1 0.1 2.2 2 1 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system OAD_gamma PF04277.13 KEG15275.1 - 9.7 6.9 11.9 2.4 8.8 4.8 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PTR2 PF00854.21 KEG15276.1 - 4.8e-42 144.2 5.7 3.2e-41 141.5 5.0 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KEG15276.1 - 0.002 17.2 50.6 0.03 13.3 15.2 3.6 1 1 2 3 3 3 2 Major Facilitator Superfamily TPR_16 PF13432.6 KEG15277.1 - 0.0007 20.2 0.3 0.0021 18.6 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG15277.1 - 0.0011 18.9 4.1 0.83 9.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG15277.1 - 0.003 17.3 1.7 1 9.3 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEG15277.1 - 0.034 14.7 1.2 0.072 13.6 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEG15277.1 - 0.078 13.4 0.3 0.27 11.7 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat ERG4_ERG24 PF01222.17 KEG15279.1 - 1.3e-105 353.6 17.8 1.7e-105 353.3 17.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family WD40 PF00400.32 KEG15280.1 - 0.025 15.5 1.3 6.3 7.8 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat EF-hand_7 PF13499.6 KEG15283.1 - 1.1e-10 41.7 0.1 3.6e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KEG15283.1 - 6.8e-05 22.5 0.0 0.00047 19.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KEG15283.1 - 0.0021 17.5 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KEG15283.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_9 PF14658.6 KEG15283.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain T3RM_EcoP15I_C PF18273.1 KEG15284.1 - 0.21 11.9 1.2 0.51 10.7 0.4 2.0 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain Cauli_AT PF03233.13 KEG15284.1 - 1.8 8.5 4.6 34 4.3 0.0 3.0 2 1 1 3 3 3 0 Aphid transmission protein IFT57 PF10498.9 KEG15285.1 - 2.3e-108 362.4 0.0 2.7e-108 362.2 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ALIX_LYPXL_bnd PF13949.6 KEG15285.1 - 0.0061 15.9 6.1 0.0093 15.3 6.1 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV KxDL PF10241.9 KEG15285.1 - 0.0099 16.1 5.5 0.73 10.2 0.6 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein Apolipoprotein PF01442.18 KEG15285.1 - 0.015 15.1 12.7 0.031 14.2 12.7 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KEG15285.1 - 0.018 13.0 6.7 0.025 12.6 6.7 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 KEG15285.1 - 0.025 14.7 9.4 0.084 12.9 0.8 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HBM PF16591.5 KEG15285.1 - 0.047 13.1 12.2 0.02 14.4 8.6 1.8 1 1 0 1 1 1 0 Helical bimodular sensor domain Exonuc_VII_L PF02601.15 KEG15285.1 - 0.071 12.7 6.1 0.12 11.9 5.3 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3958 PF13125.6 KEG15285.1 - 0.087 13.0 9.3 0.24 11.6 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Laminin_II PF06009.12 KEG15285.1 - 0.089 12.8 8.6 0.39 10.7 0.6 2.4 1 1 1 2 2 2 0 Laminin Domain II MCPsignal PF00015.21 KEG15285.1 - 0.13 12.0 4.8 0.13 12.1 2.2 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.11 KEG15285.1 - 0.19 10.6 11.4 0.49 9.2 10.6 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein SOGA PF11365.8 KEG15285.1 - 0.19 12.8 0.3 0.19 12.8 0.3 2.4 1 1 1 2 2 2 0 Protein SOGA FUSC PF04632.12 KEG15285.1 - 0.27 9.7 2.1 0.39 9.2 2.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 KEG15285.1 - 0.29 10.4 11.4 0.54 9.5 11.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF745 PF05335.13 KEG15285.1 - 0.29 10.8 7.5 1.3 8.7 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) AAA_13 PF13166.6 KEG15285.1 - 0.35 9.5 5.3 0.46 9.1 5.3 1.1 1 0 0 1 1 1 0 AAA domain Ead_Ea22 PF13935.6 KEG15285.1 - 0.36 11.5 5.7 1.5 9.4 5.6 2.1 1 1 0 1 1 1 0 Ead/Ea22-like protein DUF948 PF06103.11 KEG15285.1 - 0.42 10.9 7.6 0.41 10.9 1.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 KEG15285.1 - 0.61 10.6 4.4 0.93 10.0 4.4 1.2 1 0 0 1 1 1 0 AAA domain BLOC1S3 PF15753.5 KEG15285.1 - 0.65 10.1 10.3 28 4.8 10.3 3.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 OmpH PF03938.14 KEG15285.1 - 0.92 9.8 11.6 1.9 8.8 11.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 KEG15285.1 - 1.4 9.7 7.1 3.6 8.3 2.6 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Spc34 PF08657.10 KEG15285.1 - 2.8 7.7 8.6 2.3 7.9 7.0 1.6 1 1 1 2 2 2 0 DASH complex subunit Spc34 Atg14 PF10186.9 KEG15285.1 - 2.8 6.9 7.1 4.4 6.3 7.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MRP-S31 PF15433.6 KEG15285.1 - 3.2 7.4 7.6 4.5 6.8 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Vta1 PF04652.16 KEG15285.1 - 4.4 7.3 6.1 1.2 9.1 3.1 1.6 2 0 0 2 2 1 0 Vta1 like DUF1664 PF07889.12 KEG15285.1 - 4.8 7.2 10.4 20 5.2 5.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KEG15285.1 - 5.9 7.0 8.4 6.8 6.8 2.0 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KEG15285.1 - 7.5 6.6 8.7 2.5 8.1 3.9 2.3 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ANAPC3 PF12895.7 KEG15287.1 - 0.0017 18.6 0.1 0.21 11.9 0.1 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KEG15287.1 - 0.0065 16.4 0.1 6.3 7.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat FANC_SAP PF18081.1 KEG15287.1 - 0.038 14.1 0.1 6.3 7.1 0.0 3.6 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain PPR PF01535.20 KEG15287.1 - 0.11 12.8 0.0 1.1e+02 3.3 0.0 3.7 3 0 0 3 3 3 0 PPR repeat RRM_1 PF00076.22 KEG15288.1 - 2.7e-12 46.3 0.2 2.1e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_TAA1 PF03295.14 KEG15288.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal VPS13 PF16908.5 KEG15288.1 - 0.19 11.5 0.0 0.5 10.1 0.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal FoP_duplication PF13865.6 KEG15288.1 - 2.8 8.5 9.6 5.6 7.6 9.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 IGR PF09597.10 KEG15289.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 IGR protein motif BRE1 PF08647.11 KEG15290.1 - 7.4e-13 48.4 12.9 7.4e-13 48.4 12.9 11.7 5 4 7 12 12 12 5 BRE1 E3 ubiquitin ligase CEP63 PF17045.5 KEG15290.1 - 0.00039 20.4 40.6 0.00039 20.4 40.6 5.7 1 1 3 4 4 4 1 Centrosomal protein of 63 kDa TACC_C PF05010.14 KEG15290.1 - 0.0076 16.1 23.0 0.0076 16.1 23.0 8.4 1 1 7 9 9 9 3 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BES1_N PF05687.13 KEG15291.1 - 0.0022 18.4 1.5 0.0042 17.5 0.3 2.1 2 0 0 2 2 2 1 BES1/BZR1 plant transcription factor, N-terminal LRIF1 PF15741.5 KEG15291.1 - 0.23 9.9 12.6 3.4 6.1 12.6 2.1 1 1 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Nkap_C PF06047.11 KEG15292.1 - 1.3e-13 50.9 0.8 2.8e-13 49.8 0.8 1.5 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Extensin_2 PF04554.13 KEG15293.1 - 1.3e-06 28.4 85.6 4e-05 23.6 37.5 2.9 1 1 2 3 3 3 3 Extensin-like region WD40 PF00400.32 KEG15294.1 - 0.099 13.5 4.2 22 6.1 0.1 4.4 4 1 0 4 4 4 0 WD domain, G-beta repeat FYVE PF01363.21 KEG15295.1 - 0.0044 17.1 10.5 0.015 15.5 10.1 1.8 1 1 1 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 KEG15295.1 - 0.0096 16.1 4.3 0.013 15.7 4.3 1.3 1 1 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 KEG15295.1 - 0.18 11.7 8.8 0.043 13.7 5.7 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_C2H2_13 PF18508.1 KEG15295.1 - 0.33 10.6 0.2 0.33 10.6 0.2 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-C2H2_4 PF13894.6 KEG15295.1 - 3.1 8.9 13.0 5 8.2 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger RtcB PF01139.17 KEG15296.1 - 1.1e-120 403.6 0.1 1.4e-120 403.3 0.1 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB NAD_binding_9 PF13454.6 KEG15296.1 - 0.004 17.2 0.3 0.017 15.1 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.21 KEG15297.1 - 1.7e-41 142.2 0.0 3.5e-41 141.2 0.0 1.5 1 1 0 1 1 1 1 ThiF family ATG7_N PF16420.5 KEG15297.1 - 6.3e-40 137.7 0.0 8.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 KEG15297.1 - 1.1e-05 25.5 0.0 0.0037 17.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KEG15297.1 - 0.0044 16.6 0.0 0.0099 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KEG15297.1 - 0.026 13.9 0.0 0.63 9.4 0.0 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1195 PF06708.11 KEG15298.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Bul1_C PF04426.12 KEG15298.1 - 0.33 10.3 4.5 0.56 9.6 4.5 1.3 1 0 0 1 1 1 0 Bul1 C terminus Helicase_C PF00271.31 KEG15300.1 - 1.8e-15 57.2 0.1 7.6e-15 55.2 0.0 2.2 2 0 0 2 2 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KEG15300.1 - 1e-13 51.8 0.0 1.1e-05 26.0 0.0 5.1 5 0 0 5 5 5 2 Double-stranded RNA binding motif HA2 PF04408.23 KEG15300.1 - 1.8e-13 50.7 0.1 6.5e-13 48.9 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KEG15300.1 - 1.8e-10 40.9 0.1 7e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEG15300.1 - 5.6e-06 26.7 0.1 2.4e-05 24.6 0.1 2.1 1 0 0 1 1 1 1 AAA domain Dicer_dimer PF03368.14 KEG15300.1 - 3.2e-05 24.0 0.1 1.2 9.3 0.0 5.0 5 0 0 5 5 5 1 Dicer dimerisation domain AAA_19 PF13245.6 KEG15300.1 - 0.00013 22.4 0.0 0.00047 20.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KEG15300.1 - 0.0011 19.2 0.0 0.0033 17.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DND1_DSRM PF14709.7 KEG15300.1 - 0.011 16.0 0.1 0.033 14.4 0.1 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_14 PF13173.6 KEG15300.1 - 0.017 15.2 0.4 0.5 10.4 0.4 2.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KEG15300.1 - 0.021 14.2 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KEG15300.1 - 0.035 13.2 0.0 0.084 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KEG15300.1 - 0.062 13.2 0.2 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KEG15300.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KEG15300.1 - 0.096 13.2 0.2 0.39 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KEG15300.1 - 0.11 12.4 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaG_DnaB_bind PF08278.11 KEG15300.1 - 0.11 13.0 0.8 0.37 11.4 0.8 1.8 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Rad17 PF03215.15 KEG15300.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RloB PF13707.6 KEG15300.1 - 0.75 10.0 2.7 0.39 10.9 0.1 1.8 2 0 0 2 2 1 0 RloB-like protein AAA_23 PF13476.6 KEG15300.1 - 5.3 7.5 6.0 4 7.9 1.1 2.9 2 1 1 3 3 3 0 AAA domain FixQ PF05545.11 KEG15301.1 - 0.088 12.8 0.5 0.088 12.8 0.5 4.4 4 1 1 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ DC_STAMP PF07782.13 KEG15301.1 - 6.1 6.6 6.7 37 4.1 3.2 2.8 2 0 0 2 2 2 0 DC-STAMP-like protein DRMBL PF07522.14 KEG15302.1 - 1.1e-16 60.9 0.0 2.9e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KEG15302.1 - 0.012 15.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF4379 PF14311.6 KEG15304.1 - 5.4e-16 58.7 0.6 8.8e-16 58.0 0.6 1.4 1 0 0 1 1 1 1 Probable Zinc-ribbon domain zf-UBP PF02148.19 KEG15305.1 - 3.5e-19 68.9 1.7 3.5e-18 65.7 2.4 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UPF0054 PF02130.17 KEG15307.1 - 1.9e-25 89.2 0.0 2.8e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_6 PF13516.6 KEG15309.1 - 1.9e-05 24.4 1.8 0.3 11.2 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KEG15309.1 - 0.0002 21.6 0.4 0.058 13.8 0.0 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG15309.1 - 0.00024 21.2 0.6 2.4 9.0 0.1 4.0 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.6 KEG15309.1 - 0.00027 20.6 1.9 0.035 13.9 0.1 3.2 1 1 0 2 2 2 1 Leucine rich repeat LRR_2 PF07723.13 KEG15309.1 - 0.061 14.0 0.0 57 4.6 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat p450 PF00067.22 KEG15311.1 - 3.3e-58 197.6 0.0 4.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.11 KEG15311.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) AAA PF00004.29 KEG15313.1 - 1e-35 123.0 0.0 2.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KEG15313.1 - 3.9e-09 36.4 0.0 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 KEG15313.1 - 2e-05 24.6 0.1 9.8e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KEG15313.1 - 2.6e-05 23.9 0.0 7.9e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEG15313.1 - 0.00038 20.2 0.1 0.0039 16.9 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEG15313.1 - 0.00049 20.5 0.0 0.024 15.0 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEG15313.1 - 0.00054 19.9 0.2 0.73 9.7 0.0 2.3 1 1 1 2 2 2 2 NACHT domain AAA_24 PF13479.6 KEG15313.1 - 0.0093 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEG15313.1 - 0.011 16.0 0.2 0.13 12.5 0.2 2.6 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEG15313.1 - 0.012 15.0 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KEG15313.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 KEG15313.1 - 0.026 14.1 0.0 0.076 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KEG15313.1 - 0.045 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain IstB_IS21 PF01695.17 KEG15313.1 - 0.046 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KEG15313.1 - 0.12 11.8 0.2 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_2 PF07724.14 KEG15313.1 - 0.14 12.3 0.0 0.67 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 KEG15313.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 KaiC VPS9 PF02204.18 KEG15314.1 - 7.7e-06 26.1 0.0 6.2e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain NUP PF06516.11 KEG15315.1 - 0.015 14.5 0.3 0.015 14.5 0.3 1.5 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) PGA_cap PF09587.10 KEG15316.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Tyr_Deacylase PF02580.16 KEG15318.1 - 1.4e-27 97.0 0.0 1.8e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Complex1_LYR PF05347.15 KEG15319.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) RyR PF02026.16 KEG15319.1 - 0.03 14.5 0.0 0.31 11.2 0.0 2.2 2 1 0 2 2 2 0 RyR domain Rib_hydrolayse PF02267.17 KEG15319.1 - 0.04 13.3 0.1 0.063 12.7 0.0 1.4 2 0 0 2 2 2 0 ADP-ribosyl cyclase POLO_box PF00659.18 KEG15319.1 - 0.065 13.4 0.1 0.099 12.8 0.1 1.6 1 1 0 1 1 1 0 POLO box duplicated region Aldose_epim PF01263.20 KEG15320.1 - 1.5e-37 129.5 0.2 5e-37 127.8 0.2 1.7 1 1 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.25 KEG15321.1 - 3e-18 66.4 0.0 0.00028 20.5 0.0 6.1 5 1 0 6 6 6 6 HECT-domain (ubiquitin-transferase) Glyco_hydro_65C PF03633.15 KEG15321.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Lactamase_B PF00753.27 KEG15322.1 - 0.0012 18.8 3.0 0.0034 17.4 3.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily LIX1 PF14954.6 KEG15322.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Limb expression 1 Lactamase_B_2 PF12706.7 KEG15322.1 - 0.08 12.5 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HAGH_C PF16123.5 KEG15322.1 - 0.084 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Beta-Casp PF10996.8 KEG15323.1 - 6.5e-32 110.1 0.0 1.8e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KEG15323.1 - 3.5e-24 85.9 0.1 7e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.8 KEG15323.1 - 5.1e-24 85.0 0.1 8.8e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_6 PF16661.5 KEG15323.1 - 1.9e-17 63.4 0.0 2.2e-16 59.9 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KEG15323.1 - 1.8e-13 50.2 0.0 3.7e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KEG15323.1 - 1.6e-10 40.8 0.1 3.7e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEG15323.1 - 0.00046 20.1 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lipase_2 PF01674.18 KEG15323.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) Topoisom_I PF01028.20 KEG15324.1 - 2.9e-91 304.9 1.2 4.7e-91 304.2 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KEG15324.1 - 1.1e-89 299.6 2.7 1.1e-89 299.6 2.7 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4806 PF16064.5 KEG15324.1 - 0.041 14.2 0.6 0.21 11.9 0.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) AP2 PF00847.20 KEG15324.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.5 2 0 0 2 2 2 0 AP2 domain DUF2115 PF09888.9 KEG15324.1 - 3.6 8.1 0.0 3.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) MID_MedPIWI PF18296.1 KEG15324.1 - 7.8 6.2 13.5 5.5 6.7 11.5 1.9 2 0 0 2 2 2 0 MID domain of medPIWI LRR_9 PF14580.6 KEG15325.1 - 0.00015 21.3 0.1 0.00043 19.8 0.1 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KEG15325.1 - 0.0012 19.2 2.6 0.012 16.0 0.1 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF4200 PF13863.6 KEG15325.1 - 0.023 15.1 2.2 0.053 13.9 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) LRR_8 PF13855.6 KEG15325.1 - 0.052 13.3 2.5 0.12 12.1 2.5 1.7 1 0 0 1 1 1 0 Leucine rich repeat HIP1_clath_bdg PF16515.5 KEG15325.1 - 0.18 12.5 4.2 0.54 10.9 4.2 1.9 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KEG15325.1 - 0.65 8.8 5.1 1.2 8.0 5.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 KEG15325.1 - 1.1 9.3 2.9 2.5 8.1 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Neuromodulin PF06614.11 KEG15325.1 - 3.7 7.7 17.2 0.3 11.3 11.9 1.9 2 0 0 2 2 2 0 Neuromodulin zf-RanBP PF00641.18 KEG15326.1 - 0.00015 21.0 2.4 0.00028 20.1 2.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-CCCH_4 PF18044.1 KEG15326.1 - 0.0083 15.9 1.5 0.0083 15.9 1.5 2.8 3 0 0 3 3 3 1 CCCH-type zinc finger Metal_resist PF13801.6 KEG15326.1 - 0.042 14.1 0.1 0.081 13.1 0.1 1.5 1 0 0 1 1 1 0 Heavy-metal resistance zf-tcix PF14952.6 KEG15326.1 - 0.058 13.0 1.7 0.15 11.7 1.7 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Amidinotransf PF02274.17 KEG15327.1 - 5e-15 55.4 0.0 1.8e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Amidinotransferase Gp49 PF05973.14 KEG15327.1 - 0.076 13.2 0.7 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) LRR_6 PF13516.6 KEG15328.1 - 0.027 14.5 0.0 0.2 11.8 0.0 2.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 KEG15328.1 - 0.039 14.4 0.1 0.36 11.3 0.1 2.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG15328.1 - 0.067 13.0 0.1 0.25 11.2 0.1 2.0 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.33 KEG15328.1 - 0.32 11.7 2.1 6.9 7.6 0.0 3.2 4 0 0 4 4 4 0 Leucine Rich Repeat TPR_12 PF13424.6 KEG15329.1 - 4.3e-35 119.9 20.5 4.5e-09 36.5 2.7 6.7 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KEG15329.1 - 1.7e-30 104.0 29.5 1.4e-08 34.3 0.0 7.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KEG15329.1 - 3e-15 55.1 18.1 8e-05 22.6 0.3 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEG15329.1 - 3.1e-10 39.3 16.8 1.2e-05 24.9 0.1 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG15329.1 - 2.8e-05 23.7 20.0 0.14 12.0 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG15329.1 - 3.4e-05 23.6 22.7 0.35 11.1 0.2 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG15329.1 - 0.00013 22.6 10.8 0.055 14.1 2.1 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEG15329.1 - 0.00016 21.8 10.3 0.67 10.5 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KEG15329.1 - 0.00037 20.5 0.8 3.9 7.7 0.1 3.5 1 1 2 3 3 3 1 Rapsyn N-terminal myristoylation and linker region DUF2225 PF09986.9 KEG15329.1 - 0.00039 20.2 4.6 0.16 11.7 0.3 4.0 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF3856 PF12968.7 KEG15329.1 - 0.004 17.2 0.7 0.54 10.3 0.0 3.8 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) DUF627 PF04781.12 KEG15329.1 - 0.0081 16.2 6.1 2.7 8.1 0.5 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF627) RPN6_N PF18055.1 KEG15329.1 - 0.011 16.1 0.0 6.9 7.1 0.0 2.7 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain SusD_RagB PF07980.11 KEG15329.1 - 0.056 13.0 0.5 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 SusD family HEPN_RnaseLS PF18869.1 KEG15329.1 - 0.077 13.1 0.2 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 RnaseLS-like HEPN TPR_14 PF13428.6 KEG15329.1 - 0.085 13.7 14.7 7.6 7.7 0.8 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_5 PF12688.7 KEG15329.1 - 0.11 12.8 4.4 0.77 10.0 0.1 3.1 2 1 1 3 3 3 0 Tetratrico peptide repeat TPR_6 PF13174.6 KEG15329.1 - 0.23 12.2 16.9 10 7.0 0.5 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat MnmE_helical PF12631.7 KEG15329.1 - 0.26 11.4 1.5 0.52 10.4 0.1 2.2 2 1 0 2 2 2 0 MnmE helical domain RPN7 PF10602.9 KEG15329.1 - 1 9.1 5.6 16 5.1 0.1 3.8 2 2 2 4 4 4 0 26S proteasome subunit RPN7 DUF357 PF04010.13 KEG15329.1 - 1.4 9.0 5.2 18 5.5 0.0 3.9 5 0 0 5 5 3 0 Protein of unknown function (DUF357) TPR_11 PF13414.6 KEG15329.1 - 1.5 8.6 9.8 2 8.2 0.0 4.6 6 1 0 6 6 5 0 TPR repeat PPR PF01535.20 KEG15329.1 - 6.6 7.2 13.4 2.8 8.4 0.1 5.2 7 0 0 7 7 6 0 PPR repeat TIP49 PF06068.13 KEG15330.1 - 1.8e-167 557.0 0.7 2.4e-167 556.5 0.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KEG15330.1 - 1.3e-20 73.3 0.0 9.1e-20 70.6 0.1 2.5 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KEG15330.1 - 2.4e-11 44.2 1.1 3.7e-07 30.6 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEG15330.1 - 2.5e-11 43.6 0.1 5.3e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEG15330.1 - 1.9e-06 28.2 0.1 0.032 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEG15330.1 - 8.4e-06 26.3 0.7 0.0017 18.7 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KEG15330.1 - 0.0012 18.3 0.2 0.051 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEG15330.1 - 0.0015 18.5 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEG15330.1 - 0.0072 16.5 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEG15330.1 - 0.0075 16.6 2.6 2.7 8.3 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEG15330.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KEG15330.1 - 0.014 15.4 0.4 1.4 8.9 0.1 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TFIID-31kDa PF02291.15 KEG15330.1 - 0.016 15.3 0.1 0.44 10.6 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DnaB_C PF03796.15 KEG15330.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KEG15330.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEG15330.1 - 0.027 14.3 1.1 0.12 12.1 1.2 2.1 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEG15330.1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KEG15330.1 - 0.065 13.0 0.3 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KEG15330.1 - 0.069 12.7 0.1 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KEG15330.1 - 0.086 13.4 0.1 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG15330.1 - 0.087 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SET PF00856.28 KEG15331.1 - 1.8e-07 31.7 0.0 4.3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 SET domain AAA PF00004.29 KEG15332.1 - 1.4e-50 171.1 0.0 6.6e-38 130.1 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KEG15332.1 - 1.4e-14 54.3 0.2 3e-14 53.2 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 KEG15332.1 - 2.3e-09 37.8 2.3 0.0056 17.1 0.1 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KEG15332.1 - 1e-07 32.2 0.0 0.0011 19.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEG15332.1 - 1.2e-06 28.9 3.7 0.042 14.1 0.1 4.0 3 2 2 5 5 4 2 AAA domain AAA_7 PF12775.7 KEG15332.1 - 6.7e-06 25.7 0.0 0.059 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 KEG15332.1 - 1.3e-05 24.8 0.0 0.0044 16.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KEG15332.1 - 2.6e-05 24.6 0.0 0.041 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KEG15332.1 - 3.2e-05 24.4 0.7 0.65 10.5 0.0 4.1 4 0 0 4 4 3 1 ABC transporter DUF815 PF05673.13 KEG15332.1 - 0.0001 21.6 0.0 0.15 11.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 KEG15332.1 - 0.00017 21.5 1.0 0.94 9.4 0.1 3.6 2 1 1 3 3 3 1 NACHT domain AAA_5 PF07728.14 KEG15332.1 - 0.00036 20.6 0.0 0.36 10.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KEG15332.1 - 0.00093 19.2 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEG15332.1 - 0.00099 18.7 0.8 2.7 7.5 0.0 4.5 3 1 2 5 5 5 1 AAA domain RuvB_N PF05496.12 KEG15332.1 - 0.0013 18.5 0.0 0.85 9.4 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KEG15332.1 - 0.0018 17.6 0.0 0.47 9.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 KEG15332.1 - 0.0018 18.8 0.1 0.069 13.6 0.2 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEG15332.1 - 0.0044 16.8 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_lid_3 PF17862.1 KEG15332.1 - 0.0045 16.8 0.0 0.062 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain Rad17 PF03215.15 KEG15332.1 - 0.007 16.3 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KEG15332.1 - 0.0098 16.3 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Vps4_C PF09336.10 KEG15332.1 - 0.011 15.8 0.1 0.044 13.8 0.1 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KEG15332.1 - 0.011 15.9 0.0 0.13 12.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) T2SSE PF00437.20 KEG15332.1 - 0.014 14.5 0.0 0.3 10.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 KEG15332.1 - 0.016 15.5 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEG15332.1 - 0.021 14.8 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KEG15332.1 - 0.035 14.0 0.9 1.5 8.7 0.0 2.9 3 0 0 3 3 3 0 NTPase ATPase_2 PF01637.18 KEG15332.1 - 0.042 13.8 0.0 5.2 6.9 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Kinesin PF00225.23 KEG15332.1 - 0.044 12.7 0.0 2.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Kinesin motor domain AAA_17 PF13207.6 KEG15332.1 - 0.066 13.6 0.2 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KEG15332.1 - 0.083 12.7 0.1 34 4.2 0.0 3.3 3 1 0 3 3 3 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KEG15332.1 - 0.12 12.0 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain SMC_N PF02463.19 KEG15332.1 - 0.13 11.6 0.0 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Pkinase PF00069.25 KEG15334.1 - 5.6e-62 209.5 0.0 8e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15334.1 - 9.5e-34 116.8 0.0 1.5e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.6 KEG15334.1 - 3.9e-29 101.3 0.0 8e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.24 KEG15334.1 - 1.4e-12 47.6 0.4 2.9e-12 46.6 0.4 1.4 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 KEG15334.1 - 4e-06 26.4 0.0 6.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.21 KEG15334.1 - 0.0026 17.8 9.7 0.0026 17.8 9.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger FTA2 PF13095.6 KEG15334.1 - 0.0068 16.0 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KEG15334.1 - 0.024 13.6 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KEG15334.1 - 0.067 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DZR PF12773.7 KEG15334.1 - 0.47 10.5 10.1 7.8 6.6 6.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-UDP PF14569.6 KEG15334.1 - 6.7 6.9 8.2 5.8 7.1 5.7 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 KEG15334.1 - 8.1 6.4 10.6 20 5.2 10.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 KEG15336.1 - 5.1e-10 39.2 0.0 7.2e-09 35.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15336.1 - 3e-07 30.0 0.0 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CFAP91 PF14738.6 KEG15336.1 - 0.59 10.2 12.5 1.4 8.9 12.5 1.6 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 SARAF PF06682.12 KEG15336.1 - 2.5 7.7 15.7 0.098 12.3 7.0 2.2 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3342 PF11822.8 KEG15339.1 - 7.1e-37 125.5 0.0 1.7e-36 124.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) TruD PF01142.18 KEG15340.1 - 4e-29 101.7 0.0 1.3e-26 93.4 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Helicase_C_2 PF13307.6 KEG15342.1 - 6.4e-42 143.6 0.0 1.3e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KEG15342.1 - 6.2e-36 123.7 0.0 1.1e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 KEG15342.1 - 0.0012 18.6 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KEG15342.1 - 0.015 15.3 0.0 3.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Kelch_3 PF13415.6 KEG15343.1 - 2.3e-13 50.1 0.4 0.00011 22.4 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 KEG15343.1 - 1.7e-12 47.1 1.9 0.00042 20.3 0.1 3.8 2 1 1 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG15343.1 - 7.6e-12 44.9 0.3 3.1e-06 27.0 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 KEG15343.1 - 3.8e-05 23.8 2.7 0.017 15.4 0.0 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KEG15343.1 - 0.00015 21.2 2.0 0.38 10.4 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KEG15343.1 - 0.2 11.7 1.9 4.3 7.5 0.0 3.4 3 0 0 3 3 3 0 Kelch motif TPP_enzyme_N PF02776.18 KEG15344.1 - 1.4e-21 76.9 0.1 1.4e-21 76.9 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEG15344.1 - 3.4e-11 43.1 6.3 3.6e-09 36.6 3.7 3.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UbiA PF01040.18 KEG15345.1 - 4.1e-40 137.7 22.1 4.1e-40 137.7 22.1 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family Hydrolase_3 PF08282.12 KEG15347.1 - 2e-54 185.0 0.5 2e-38 132.6 0.1 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEG15347.1 - 9.2e-11 41.7 0.0 4.9e-05 23.0 0.0 2.6 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KEG15347.1 - 6.1e-06 26.7 1.0 0.029 14.7 0.1 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEG15347.1 - 0.015 15.4 0.1 0.089 12.9 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KEG15347.1 - 0.018 14.7 2.9 0.14 11.7 0.0 3.1 1 1 2 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Trehalose_PPase PF02358.16 KEG15347.1 - 0.02 14.0 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase HAD PF12710.7 KEG15347.1 - 0.036 14.5 0.1 2.9 8.3 0.0 2.7 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase PALP PF00291.25 KEG15348.1 - 1.1e-47 162.9 0.0 1.4e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3847 PF12958.7 KEG15348.1 - 0.23 11.6 1.1 2.6 8.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) ThiF PF00899.21 KEG15349.1 - 2.7e-12 46.6 0.3 3.9e-12 46.0 0.1 1.5 2 0 0 2 2 2 1 ThiF family Sacchrp_dh_NADP PF03435.18 KEG15350.1 - 8.7e-19 68.1 0.0 1.7e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KEG15350.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEG15350.1 - 0.00063 19.3 0.1 0.0016 18.0 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KEG15350.1 - 0.0028 18.1 0.0 0.0093 16.4 0.0 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEG15350.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEG15350.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 KEG15350.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KEG15350.1 - 0.071 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_M8 PF01457.16 KEG15352.1 - 2.3e-84 284.0 0.0 3.4e-77 260.3 0.0 2.9 1 1 1 2 2 2 2 Leishmanolysin Mucin PF01456.17 KEG15352.1 - 0.0089 16.0 2.9 0.0089 16.0 2.9 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein dsDNA_bind PF01984.20 KEG15353.1 - 8.2e-20 71.1 9.8 1.2e-19 70.6 9.8 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain LIN37 PF15306.6 KEG15353.1 - 0.031 14.5 1.4 0.046 13.9 1.4 1.2 1 0 0 1 1 1 0 LIN37 Lipase_chap PF03280.14 KEG15353.1 - 0.069 13.1 9.2 0.092 12.7 9.2 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF2849 PF11011.8 KEG15353.1 - 1 10.1 3.8 0.85 10.3 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2849) BCIP PF13862.6 KEG15354.1 - 2.2e-32 112.5 1.2 3e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 p21-C-terminal region-binding protein DnaJ PF00226.31 KEG15355.1 - 2.6e-07 30.7 0.0 6.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_9 PF14369.6 KEG15355.1 - 0.34 11.2 3.2 14 6.1 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon DHHC PF01529.20 KEG15356.1 - 7.6e-25 87.6 0.3 7.6e-25 87.6 0.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase RIBIOP_C PF04950.12 KEG15357.1 - 4.2e-77 259.5 0.0 4.2e-77 259.5 0.0 2.3 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KEG15357.1 - 5.6e-25 87.2 0.0 2e-24 85.4 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KEG15357.1 - 0.00011 22.6 0.0 0.00038 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEG15357.1 - 0.00022 21.5 0.0 0.00067 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KEG15357.1 - 0.00057 20.0 0.1 0.0022 18.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KEG15357.1 - 0.00066 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KEG15357.1 - 0.0021 18.6 0.0 0.017 15.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 KEG15357.1 - 0.0024 17.4 0.0 0.14 11.7 0.0 2.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KEG15357.1 - 0.0037 17.8 1.0 1.3 9.5 0.4 3.3 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KEG15357.1 - 0.0094 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KEG15357.1 - 0.016 15.1 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 KEG15357.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KEG15357.1 - 0.023 15.2 0.0 0.34 11.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEG15357.1 - 0.033 14.6 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEG15357.1 - 0.035 14.3 0.1 0.035 14.3 0.1 2.5 2 1 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 KEG15357.1 - 0.041 13.8 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KEG15357.1 - 0.047 12.9 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KEG15357.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEG15357.1 - 0.091 12.7 0.2 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2992 PF11208.8 KEG15357.1 - 0.37 11.0 17.7 2.1 8.6 13.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) AAA_11 PF13086.6 KEG15357.1 - 3.6 7.3 14.1 0.99 9.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain Methyltransf_16 PF10294.9 KEG15359.1 - 2e-14 53.7 0.0 5.7e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase DUF4586 PF15239.6 KEG15360.1 - 2e-27 97.2 0.4 2.4e-27 96.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Kinesin PF00225.23 KEG15361.1 - 6.9e-84 281.6 0.0 1.6e-83 280.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEG15361.1 - 1.6e-39 135.2 0.1 2.8e-38 131.2 0.1 2.4 1 1 0 1 1 1 1 Microtubule binding Aldolase_II PF00596.21 KEG15362.1 - 3.3e-44 151.0 0.0 3.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SNF2_N PF00176.23 KEG15363.1 - 1.6e-41 142.2 0.0 2.4e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEG15363.1 - 1.2e-10 41.7 0.0 2.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KEG15363.1 - 6.1e-07 29.2 9.0 1.4e-06 28.1 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEG15363.1 - 4.3e-06 26.6 9.6 8.9e-06 25.6 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KEG15363.1 - 3.5e-05 24.0 10.3 9.7e-05 22.6 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEG15363.1 - 6.3e-05 22.7 9.9 0.00015 21.5 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEG15363.1 - 0.00015 21.5 10.2 0.00041 20.1 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG15363.1 - 0.00043 20.2 10.0 0.0011 18.9 10.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 KEG15363.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG15363.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 KEG15363.1 - 0.019 14.8 9.1 0.044 13.6 9.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KEG15363.1 - 0.023 14.6 5.0 0.058 13.3 5.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Helicase_C_2 PF13307.6 KEG15363.1 - 0.037 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain zf-C3HC4_4 PF15227.6 KEG15363.1 - 0.061 13.5 10.4 0.19 11.9 10.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KEG15363.1 - 0.2 11.9 8.6 0.085 13.2 4.8 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KEG15363.1 - 0.28 10.8 5.0 0.61 9.7 5.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KEG15363.1 - 0.91 9.6 5.4 2.1 8.5 5.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 KEG15363.1 - 7.1 6.6 8.5 7.3 6.6 4.5 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rep_fac-A_C PF08646.10 KEG15364.1 - 2.4e-45 153.8 1.2 1.1e-42 145.2 0.2 3.1 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KEG15364.1 - 3.5e-21 75.0 1.6 1.9e-19 69.4 0.5 2.6 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KEG15364.1 - 1.2e-11 44.4 0.1 3.1e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KEG15364.1 - 5e-07 29.7 0.0 7.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 KEG15364.1 - 0.013 15.7 0.0 0.063 13.5 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DZR PF12773.7 KEG15364.1 - 0.017 15.2 0.8 0.034 14.2 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KEG15364.1 - 0.017 15.1 0.2 0.033 14.2 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 KEG15364.1 - 4.3 7.0 8.3 2.8 7.6 0.3 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DEAD PF00270.29 KEG15366.1 - 1.8e-21 76.7 0.0 2.2e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEG15366.1 - 8.9e-05 22.5 0.0 0.00017 21.6 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KEG15366.1 - 0.00026 20.1 0.0 0.00053 19.1 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KEG15366.1 - 0.0015 18.8 0.0 0.0062 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEG15366.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KEG15366.1 - 0.013 15.9 0.2 0.029 14.7 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain UvrD-helicase PF00580.21 KEG15366.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KEG15366.1 - 0.095 13.0 0.1 0.26 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEG15366.1 - 0.11 12.2 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KEG15366.1 - 0.12 11.7 0.0 0.69 9.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.16 KEG15366.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Cyclase PF04199.13 KEG15367.1 - 3.6e-11 43.5 0.0 4.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase NLRC4_HD2 PF17776.1 KEG15368.1 - 0.07 13.7 0.2 11 6.5 0.1 3.0 2 1 0 2 2 2 0 NLRC4 helical domain HD2 YlqD PF11068.8 KEG15369.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 YlqD protein PI3_PI4_kinase PF00454.27 KEG15372.1 - 2.4e-45 155.3 0.2 4.8e-45 154.3 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KEG15372.1 - 3.8e-16 59.2 3.7 2.1e-14 53.5 3.5 2.9 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 KEG15372.1 - 3.3e-08 33.2 0.6 1.1e-07 31.6 0.6 2.0 1 0 0 1 1 1 1 FATC domain UME PF08064.13 KEG15372.1 - 3.5e-06 26.9 0.4 3.4e-05 23.7 0.0 2.8 2 0 0 2 2 2 1 UME (NUC010) domain TPR_1 PF00515.28 KEG15372.1 - 0.026 14.3 1.2 1.6 8.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEG15372.1 - 0.5 10.6 2.5 9.1 6.7 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MIP-T3 PF10243.9 KEG15373.1 - 2e-24 85.8 0.0 4.1e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain DUF4746 PF15928.5 KEG15373.1 - 0.0062 16.0 1.1 2.6 7.4 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4746) TruB_N PF01509.18 KEG15373.1 - 0.016 15.6 1.7 0.031 14.6 1.7 1.5 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Syntaxin-18_N PF10496.9 KEG15373.1 - 1.5 9.1 5.3 13 6.1 0.1 2.7 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus BRF1 PF07741.13 KEG15373.1 - 2.6 8.4 9.5 7.7 6.9 9.6 1.8 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Presenilin PF01080.17 KEG15373.1 - 3.8 6.2 5.2 4.8 5.9 5.2 1.1 1 0 0 1 1 1 0 Presenilin SHR3_chaperone PF08229.11 KEG15373.1 - 8.6 5.3 6.2 15 4.5 6.2 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 rRNA_processing PF08524.11 KEG15375.1 - 3.8e-07 30.2 31.1 5.9e-07 29.6 28.7 2.3 1 1 1 2 2 2 1 rRNA processing Peptidase_M41 PF01434.18 KEG15377.1 - 3e-49 167.5 0.2 5.5e-49 166.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEG15377.1 - 3.5e-41 140.7 0.0 8.5e-41 139.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG15377.1 - 1.7e-05 25.3 0.2 0.00029 21.3 0.2 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 KEG15377.1 - 0.00074 19.3 0.2 0.0031 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 KEG15377.1 - 0.002 18.4 0.2 0.022 15.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KEG15377.1 - 0.0072 15.6 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KEG15377.1 - 0.013 15.3 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KEG15377.1 - 0.019 14.3 0.1 0.07 12.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KEG15377.1 - 0.024 14.6 0.3 0.21 11.6 0.3 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KEG15377.1 - 0.031 14.0 0.1 0.16 11.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KEG15377.1 - 0.061 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KEG15377.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KEG15377.1 - 0.072 13.0 0.0 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KEG15377.1 - 0.26 10.8 0.9 1.3 8.5 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 KEG15377.1 - 0.78 9.8 3.4 1.3 9.1 0.2 2.8 2 1 1 3 3 3 0 AAA domain (Cdc48 subfamily) Chromo PF00385.24 KEG15378.1 - 0.2 11.6 0.0 0.51 10.3 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain YqaJ PF09588.10 KEG15379.1 - 2.7e-40 137.9 0.0 4e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain zf-C3Hc3H PF13891.6 KEG15380.1 - 0.11 12.8 0.7 6.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Potential DNA-binding domain Methyltransf_31 PF13847.6 KEG15381.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PSP1 PF04468.12 KEG15382.1 - 1.5e-23 82.9 0.1 2.4e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region CLU PF13236.6 KEG15383.1 - 8.3e-29 101.0 0.0 1.2e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KEG15383.1 - 2.1e-07 31.1 0.0 3.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 ArfGap PF01412.18 KEG15385.1 - 2.2e-41 140.6 0.0 3.2e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.21 KEG15386.1 - 5.9e-84 282.4 0.0 1.1e-83 281.5 0.0 1.4 1 1 0 1 1 1 1 Phosphomannose isomerase type I PIF1 PF05970.14 KEG15387.1 - 1.4e-37 129.8 0.0 7.3e-30 104.3 0.0 3.1 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KEG15387.1 - 7.5e-12 45.4 0.0 1.5e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KEG15387.1 - 2.7e-05 24.0 0.1 0.18 11.5 0.0 3.3 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KEG15387.1 - 4.9e-05 23.1 0.2 0.0002 21.1 0.1 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KEG15387.1 - 0.00099 19.5 0.2 0.0022 18.4 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEG15387.1 - 0.0028 17.9 0.2 0.015 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KEG15387.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KEG15387.1 - 0.019 15.3 0.1 0.09 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEG15387.1 - 0.028 14.4 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SH3_13 PF18335.1 KEG15387.1 - 0.031 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain MeaB PF03308.16 KEG15387.1 - 0.036 13.0 0.1 0.073 12.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KEG15387.1 - 0.044 13.7 0.5 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 KEG15387.1 - 0.085 12.1 0.3 0.25 10.6 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KEG15387.1 - 0.088 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2791 PF10923.8 KEG15387.1 - 0.11 11.4 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIN_11 PF18479.1 KEG15389.1 - 0.0021 18.2 0.1 0.7 10.1 0.0 2.4 1 1 1 2 2 2 2 PIN like domain acVLRF1 PF18859.1 KEG15389.1 - 0.15 12.4 1.1 0.19 12.0 0.2 1.6 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Anti-TRAP PF15777.5 KEG15391.1 - 0.11 12.5 0.1 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SPX PF03105.19 KEG15391.1 - 0.47 10.3 6.8 0.63 9.9 6.8 1.2 1 0 0 1 1 1 0 SPX domain Mtc PF03820.17 KEG15394.1 - 0.017 14.2 2.2 2.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Tricarboxylate carrier NEMO PF11577.8 KEG15394.1 - 8.8 6.4 16.2 3.7 7.6 1.5 3.7 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO NAD_synthase PF02540.17 KEG15395.1 - 8e-36 123.4 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 NAD synthase PAPS_reduct PF01507.19 KEG15395.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 KEG15395.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF4666 PF15697.5 KEG15396.1 - 0.055 14.2 0.2 0.16 12.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) CPP1-like PF11833.8 KEG15396.1 - 0.33 10.6 0.5 0.65 9.6 0.5 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DNA_pol_E_B PF04042.16 KEG15397.1 - 1.3e-10 41.0 0.0 3.2e-09 36.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.14 KEG15398.1 - 1.1e-34 120.2 1.2 3.7e-34 118.5 1.2 1.7 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 KEG15398.1 - 0.013 15.5 0.2 0.47 10.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG15398.1 - 0.063 14.1 15.4 0.88 10.6 0.5 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TFIIS_M PF07500.14 KEG15398.1 - 0.074 13.5 0.6 0.2 12.2 0.6 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain TPR_19 PF14559.6 KEG15398.1 - 0.098 13.2 12.7 1.8 9.1 0.3 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 KEG15399.1 - 3.2e-49 164.8 2.4 8.2e-18 64.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein TNT PF14021.6 KEG15399.1 - 0.092 13.3 0.1 0.17 12.5 0.1 1.3 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin PP2C PF00481.21 KEG15400.1 - 1.9e-71 240.7 0.0 2.8e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C MNE1 PF13762.6 KEG15400.1 - 0.039 14.0 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component PP2C_2 PF13672.6 KEG15400.1 - 0.041 13.5 0.0 0.081 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C SpoIIE PF07228.12 KEG15400.1 - 0.16 11.8 0.0 2.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) MFS_1 PF07690.16 KEG15401.1 - 5.9e-25 87.9 21.3 8.5e-25 87.4 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glycos_transf_2 PF00535.26 KEG15402.1 - 4.9e-05 23.2 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Kinesin PF00225.23 KEG15403.1 - 2.4e-71 240.4 0.0 1.3e-70 238.0 0.0 2.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KEG15403.1 - 1.5e-20 73.6 0.0 5e-20 71.9 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding Exonuc_VII_L PF02601.15 KEG15403.1 - 0.12 12.0 15.7 2.9 7.4 15.6 2.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit ANAPC5 PF12862.7 KEG15403.1 - 0.3 11.2 2.3 0.85 9.7 2.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Herpes_DNAp_acc PF04929.12 KEG15403.1 - 0.79 8.6 3.8 1.3 7.9 3.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.13 KEG15403.1 - 1.1 9.2 11.1 1.9 8.4 11.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF812 PF05667.11 KEG15403.1 - 1.8 7.3 16.5 3.4 6.4 10.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) COG2 PF06148.11 KEG15403.1 - 1.9 8.5 10.1 0.2 11.7 1.6 3.0 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FapA PF03961.13 KEG15403.1 - 2.9 6.4 7.2 0.87 8.1 2.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A TerB_C PF15615.6 KEG15403.1 - 3.6 7.9 10.8 5.9 7.2 10.0 1.8 1 1 0 1 1 1 0 TerB-C domain ATG16 PF08614.11 KEG15403.1 - 3.9 7.6 33.7 0.42 10.8 22.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 KEG15403.1 - 9.1 6.0 26.6 16 5.2 26.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HEAT_2 PF13646.6 KEG15404.1 - 8e-12 45.4 2.8 0.048 14.0 0.0 6.2 5 2 1 6 6 6 4 HEAT repeats Acetyltransf_13 PF13880.6 KEG15405.1 - 2.8e-21 75.3 0.0 5.8e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 KEG15405.1 - 0.0021 18.4 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEG15405.1 - 0.03 14.5 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C3HC4_3 PF13920.6 KEG15407.1 - 0.035 14.0 7.3 0.11 12.4 7.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 KEG15407.1 - 0.097 13.0 1.4 2.8 8.3 0.6 2.6 2 0 0 2 2 2 0 C1 domain zf-RING_13 PF17977.1 KEG15407.1 - 0.29 11.3 9.0 0.35 11.0 4.2 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LRR_4 PF12799.7 KEG15409.1 - 4.1e-14 52.5 9.2 9.2e-06 25.9 0.0 5.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG15409.1 - 4.9e-13 48.6 8.9 8.1e-05 22.3 0.3 3.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 KEG15409.1 - 5.3e-07 29.2 8.0 3.6 7.9 0.3 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KEG15409.1 - 0.0017 17.9 1.1 0.34 10.4 0.0 3.1 2 1 1 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 KEG15409.1 - 0.052 14.1 12.9 21 6.2 0.1 6.1 6 2 1 7 7 7 0 Leucine Rich Repeat FmiP_Thoc5 PF09766.9 KEG15409.1 - 1 8.6 4.1 0.99 8.6 0.1 2.5 3 0 0 3 3 3 0 Fms-interacting protein/Thoc5 14-3-3 PF00244.20 KEG15410.1 - 0.029 13.9 0.1 0.032 13.7 0.1 1.1 1 0 0 1 1 1 0 14-3-3 protein Lipin_mid PF16876.5 KEG15410.1 - 0.13 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain LRR_6 PF13516.6 KEG15411.1 - 0.0041 17.1 0.2 33 4.9 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 KEG15411.1 - 0.014 15.8 0.9 10 6.7 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEG15411.1 - 1.8 9.4 8.5 72 4.5 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat ZZ PF00569.17 KEG15412.1 - 7.2e-09 35.3 23.0 8.3e-08 31.9 7.7 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 KEG15412.1 - 0.11 12.9 11.9 0.077 13.3 0.8 3.0 2 0 0 2 2 2 0 C1 domain BCDHK_Adom3 PF10436.9 KEG15413.1 - 1.4e-18 67.2 0.1 2.3e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEG15413.1 - 2.4e-09 37.7 0.0 8.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEG15413.1 - 0.00011 22.1 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Enkurin PF13864.6 KEG15414.1 - 3.7e-17 62.5 6.3 8.4e-17 61.4 6.3 1.6 1 0 0 1 1 1 1 Calmodulin-binding AAA_23 PF13476.6 KEG15414.1 - 0.0074 16.8 1.0 0.011 16.3 1.0 1.2 1 0 0 1 1 1 1 AAA domain SPOC PF07744.13 KEG15414.1 - 0.083 12.8 0.3 0.83 9.6 0.2 2.0 2 0 0 2 2 2 0 SPOC domain AAA_5 PF07728.14 KEG15416.1 - 1e-126 417.5 0.0 2.4e-23 82.7 0.0 7.7 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KEG15416.1 - 2.6e-41 140.1 8.4 2.1e-12 47.2 0.4 7.1 7 1 0 7 7 6 4 Midasin AAA lid domain AAA_3 PF07726.11 KEG15416.1 - 4.5e-33 113.9 0.0 1.5e-07 31.3 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG15416.1 - 2.2e-23 83.0 0.0 0.014 15.6 0.0 7.2 6 0 0 6 6 6 5 AAA domain AAA PF00004.29 KEG15416.1 - 2.4e-23 83.0 0.2 0.0011 19.4 0.0 7.5 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG15416.1 - 9.1e-23 81.5 24.3 1.7e-05 25.3 0.1 9.6 8 2 0 10 10 6 6 AAA ATPase domain AAA_7 PF12775.7 KEG15416.1 - 1.1e-22 80.4 0.4 0.0025 17.4 0.1 6.6 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KEG15416.1 - 2e-20 72.8 0.0 7.3e-20 71.0 0.0 2.1 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_6 PF12774.7 KEG15416.1 - 1.1e-19 70.6 0.0 0.017 14.1 0.0 7.9 8 0 0 8 8 7 4 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 KEG15416.1 - 1.5e-18 67.1 0.0 0.0012 18.5 0.0 6.7 6 1 0 6 6 6 3 Sigma-54 interaction domain Dynein_heavy PF03028.15 KEG15416.1 - 5.8e-17 61.9 0.0 0.01 15.9 0.0 6.3 6 0 0 6 6 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activ_2 PF14532.6 KEG15416.1 - 1.5e-16 60.8 0.6 0.0026 17.9 0.0 6.7 7 0 0 7 7 6 3 Sigma-54 interaction domain AAA_14 PF13173.6 KEG15416.1 - 8.1e-15 55.0 0.0 0.022 14.8 0.0 6.8 6 0 0 6 6 6 3 AAA domain ABC_tran PF00005.27 KEG15416.1 - 1.1e-14 55.2 0.1 0.05 14.1 0.0 7.1 6 0 0 6 6 6 2 ABC transporter TsaE PF02367.17 KEG15416.1 - 2e-14 53.7 2.4 0.021 14.8 0.1 6.5 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEG15416.1 - 9.3e-14 51.6 0.1 0.01 15.5 0.0 8.3 7 2 1 8 8 8 2 AAA domain Mg_chelatase PF01078.21 KEG15416.1 - 1.5e-11 44.0 0.2 0.43 9.9 0.0 8.2 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KEG15416.1 - 1e-10 41.6 0.1 0.1 12.3 0.0 5.4 5 0 0 5 5 4 2 IstB-like ATP binding protein AAA_29 PF13555.6 KEG15416.1 - 1.1e-10 41.0 0.4 4.5 7.1 0.0 6.9 6 0 0 6 6 6 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEG15416.1 - 2e-10 40.3 0.0 0.085 12.1 0.0 6.6 6 0 0 6 6 6 2 Zeta toxin AAA_18 PF13238.6 KEG15416.1 - 4.7e-10 40.1 0.8 1.2 9.6 0.0 7.3 7 0 0 7 7 7 3 AAA domain RsgA_GTPase PF03193.16 KEG15416.1 - 6.8e-10 39.1 2.1 1.1 9.1 0.1 6.3 6 0 0 6 6 5 2 RsgA GTPase AAA_33 PF13671.6 KEG15416.1 - 1.5e-09 38.2 0.0 1.5 9.0 0.0 7.7 8 0 0 8 8 6 1 AAA domain RNA_helicase PF00910.22 KEG15416.1 - 1.6e-09 38.1 0.3 0.16 12.4 0.0 6.8 7 0 0 7 7 6 1 RNA helicase T2SSE PF00437.20 KEG15416.1 - 2e-08 33.7 0.3 0.59 9.1 0.0 6.4 7 0 0 7 7 7 1 Type II/IV secretion system protein AAA_25 PF13481.6 KEG15416.1 - 1.3e-06 28.1 3.7 3.5 7.2 0.1 7.0 8 0 0 8 8 7 1 AAA domain DUF815 PF05673.13 KEG15416.1 - 1.8e-06 27.4 4.1 2.1 7.4 0.1 5.9 7 0 0 7 7 7 1 Protein of unknown function (DUF815) NACHT PF05729.12 KEG15416.1 - 3.8e-06 26.9 3.7 0.31 11.0 0.0 5.9 6 0 0 6 6 6 1 NACHT domain RuvB_N PF05496.12 KEG15416.1 - 4e-06 26.7 0.0 1.7 8.4 0.0 5.6 6 0 0 6 6 5 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KEG15416.1 - 1.2e-05 25.1 0.2 5.4 6.7 0.0 4.8 5 0 0 5 5 4 0 AAA domain Rad17 PF03215.15 KEG15416.1 - 1.3e-05 25.2 0.4 6.9 6.5 0.0 5.8 6 0 0 6 6 6 0 Rad17 P-loop domain AAA_19 PF13245.6 KEG15416.1 - 4.7e-05 23.8 1.0 10 6.5 0.0 5.3 4 0 0 4 4 4 0 AAA domain dNK PF01712.19 KEG15416.1 - 5.2e-05 23.2 1.2 1.8 8.3 0.0 5.6 6 0 0 6 6 6 1 Deoxynucleoside kinase DUF2791 PF10923.8 KEG15416.1 - 6.2e-05 22.0 0.1 0.36 9.6 0.0 3.4 3 0 0 3 3 3 1 P-loop Domain of unknown function (DUF2791) AAA_8 PF12780.7 KEG15416.1 - 7.7e-05 22.1 0.2 9.8 5.4 0.0 5.1 5 0 0 5 5 5 0 P-loop containing dynein motor region D4 CPT PF07931.12 KEG15416.1 - 0.00012 22.0 1.0 0.35 10.7 0.1 5.2 5 1 0 5 5 3 1 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.23 KEG15416.1 - 0.00044 20.3 0.1 27 4.9 0.0 5.0 4 0 0 4 4 4 0 50S ribosome-binding GTPase ATPase PF06745.13 KEG15416.1 - 0.00045 19.6 0.2 3.5 6.9 0.0 4.8 5 0 0 5 5 5 1 KaiC TIP49 PF06068.13 KEG15416.1 - 0.0011 18.3 2.5 3.3 6.8 0.1 4.3 5 0 0 5 5 5 1 TIP49 P-loop domain PIF1 PF05970.14 KEG15416.1 - 0.0015 17.8 1.1 3.5 6.7 0.0 5.2 6 0 0 6 6 6 1 PIF1-like helicase DEAD PF00270.29 KEG15416.1 - 0.0033 17.2 0.1 3.3 7.4 0.0 4.6 5 0 0 5 5 5 1 DEAD/DEAH box helicase NTPase_1 PF03266.15 KEG15416.1 - 0.0041 17.0 3.3 2.8 7.8 0.1 4.5 4 0 0 4 4 4 1 NTPase MeaB PF03308.16 KEG15416.1 - 0.0055 15.7 0.6 0.43 9.5 0.1 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 KEG15416.1 - 0.01 15.3 5.9 11 5.4 0.0 5.2 5 0 0 5 5 5 0 PhoH-like protein TniB PF05621.11 KEG15416.1 - 0.012 15.1 0.1 8.1 5.8 0.0 4.7 6 0 0 6 6 5 0 Bacterial TniB protein ATP-synt_ab PF00006.25 KEG15416.1 - 0.048 13.3 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KEG15416.1 - 0.085 12.6 3.9 11 5.8 0.1 4.5 6 0 0 6 6 4 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 KEG15416.1 - 0.11 11.7 0.0 14 4.8 0.0 3.7 4 0 0 4 4 4 0 KAP family P-loop domain ResIII PF04851.15 KEG15416.1 - 0.36 10.8 7.7 12 5.9 0.0 5.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit Roc PF08477.13 KEG15416.1 - 1.6 9.0 5.9 27 5.0 0.0 4.7 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase DS PF01916.17 KEG15417.1 - 5.6e-89 298.2 0.0 6.7e-89 297.9 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF948 PF06103.11 KEG15419.1 - 0.00033 20.9 0.3 0.012 15.9 0.0 1.8 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 KEG15419.1 - 0.022 15.0 0.2 0.12 12.7 0.2 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 KEG15419.1 - 0.066 13.0 0.6 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Halogen_Hydrol PF10112.9 KEG15419.1 - 0.075 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein EcKinase PF02958.20 KEG15419.1 - 0.088 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_32 PF13654.6 KEG15419.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.21 KEG15419.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PAP_central PF04928.17 KEG15421.1 - 0.021 13.8 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 0 Poly(A) polymerase central domain Kelch_6 PF13964.6 KEG15422.1 - 1.1e-26 92.1 19.1 2.9e-06 27.4 0.0 6.8 7 1 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 KEG15422.1 - 9.2e-23 80.0 19.9 2.5e-06 27.6 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KEG15422.1 - 4.6e-22 77.3 22.8 2.3e-06 27.1 0.0 7.7 7 1 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 KEG15422.1 - 1.1e-21 76.5 9.7 0.00024 21.0 0.1 5.8 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG15422.1 - 4.4e-21 74.4 17.9 4e-07 29.9 0.3 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KEG15422.1 - 2.9e-17 61.9 14.6 0.0013 18.7 0.2 7.0 7 1 0 7 7 7 5 Kelch motif PQQ_3 PF13570.6 KEG15422.1 - 0.0066 16.9 0.9 2.6 8.6 0.1 3.5 3 0 0 3 3 3 1 PQQ-like domain DUF3786 PF12654.7 KEG15425.1 - 0.13 11.9 0.0 5 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Myb_DNA-binding PF00249.31 KEG15425.1 - 0.13 12.5 1.2 48 4.3 0.0 3.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain EF-hand_7 PF13499.6 KEG15426.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair PHD_Oberon PF07227.11 KEG15427.1 - 0.03 14.2 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein V_ATPase_I PF01496.19 KEG15427.1 - 0.19 9.6 6.6 0.36 8.7 6.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec34 PF04136.15 KEG15427.1 - 3.3 7.6 12.7 0.29 11.0 1.5 3.3 2 1 1 3 3 3 0 Sec34-like family DUF1736 PF08409.11 KEG15428.1 - 2.6e-13 49.8 0.0 8.8e-13 48.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) DUF4131 PF13567.6 KEG15428.1 - 8.7 6.0 17.7 5.3 6.7 1.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MORN PF02493.20 KEG15430.1 - 4.2e-06 26.3 15.0 0.00078 19.2 0.0 6.0 6 1 0 6 6 6 2 MORN repeat Kelch_6 PF13964.6 KEG15431.1 - 4.1e-14 52.3 3.6 0.0014 18.8 0.0 4.4 2 2 2 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KEG15431.1 - 6.3e-12 45.5 3.5 0.03 14.6 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEG15431.1 - 3e-10 39.9 7.5 0.00057 19.8 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KEG15431.1 - 4.1e-09 36.0 2.2 0.0055 16.6 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KEG15431.1 - 1.9e-07 30.6 11.6 1.2e-05 24.8 0.3 4.1 4 2 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KEG15431.1 - 7.8e-06 25.8 11.8 0.0073 16.3 0.5 5.8 5 1 1 6 6 6 2 Galactose oxidase, central domain Ribosomal_L7Ae PF01248.26 KEG15432.1 - 5.7e-18 64.4 0.1 7.4e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.10 KEG15433.1 - 2.6e-06 26.9 0.0 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 2 Rgp1 Peptidase_C78 PF07910.13 KEG15434.1 - 1.1e-50 172.1 0.0 1.6e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KEG15434.1 - 0.15 11.4 0.1 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C54 Prenyltrans PF00432.21 KEG15437.1 - 2.7e-61 203.0 20.8 7.4e-13 48.0 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEG15437.1 - 8.5e-05 21.8 0.0 1 8.4 0.0 4.2 1 1 4 5 5 5 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KEG15437.1 - 0.00018 20.7 2.9 0.0007 18.8 0.1 2.8 1 1 2 3 3 3 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 KEG15437.1 - 0.36 9.8 2.4 6.2 5.7 0.0 3.1 3 1 1 4 4 4 0 A-macroglobulin TED domain RPA_interact_N PF14766.6 KEG15438.1 - 0.06 13.0 0.7 0.21 11.3 0.7 2.0 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DUF561 PF04481.12 KEG15438.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) GRIP PF01465.20 KEG15438.1 - 0.25 11.3 2.9 0.35 10.8 0.6 2.5 3 0 0 3 3 3 0 GRIP domain Lsr2 PF11774.8 KEG15439.1 - 0.035 14.2 4.2 0.62 10.2 0.0 2.5 2 0 0 2 2 2 0 Lsr2 TRPM_tetra PF16519.5 KEG15439.1 - 0.053 13.6 1.5 12 6.1 0.3 2.7 1 1 1 2 2 2 0 Tetramerisation domain of TRPM UCH PF00443.29 KEG15440.1 - 4.6e-42 144.3 0.0 7.3e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEG15440.1 - 6.8e-13 48.9 0.1 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Casc1_N PF15927.5 KEG15441.1 - 5.2e-11 42.6 8.3 1.9e-10 40.8 8.3 1.9 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus DnaJ PF00226.31 KEG15442.1 - 1.9e-08 34.3 0.2 4.3e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain OPT PF03169.15 KEG15442.1 - 0.25 9.9 0.0 0.29 9.7 0.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein GRIP PF01465.20 KEG15443.1 - 7.8e-12 44.9 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 GRIP domain Tup_N PF08581.10 KEG15443.1 - 3.5e-05 24.0 12.1 0.0014 18.9 0.7 4.1 4 0 0 4 4 4 2 Tup N-terminal DUF4407 PF14362.6 KEG15443.1 - 0.00031 20.2 19.4 0.2 11.0 0.4 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.12 KEG15443.1 - 0.012 15.4 1.9 0.012 15.4 1.9 5.2 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 KEG15443.1 - 0.058 13.6 12.7 0.073 13.2 1.3 3.7 3 1 1 4 4 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KEG15443.1 - 0.089 12.8 14.8 1.1 9.3 1.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KEG15443.1 - 0.11 12.3 22.1 1.8 8.4 0.0 5.8 3 1 3 6 6 6 0 Septum formation initiator Sh_2 PF17512.2 KEG15443.1 - 0.15 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein Atg14 PF10186.9 KEG15443.1 - 0.19 10.8 14.4 1.6 7.8 0.0 3.8 2 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 KEG15443.1 - 0.34 11.2 5.1 2 8.7 0.7 3.4 4 0 0 4 4 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad4 PF08650.10 KEG15443.1 - 0.35 10.9 4.4 18 5.4 0.1 3.9 2 1 1 3 3 3 0 DASH complex subunit Dad4 YabA PF06156.13 KEG15443.1 - 0.36 11.5 14.9 0.74 10.5 0.0 5.0 4 1 1 5 5 5 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 KEG15443.1 - 0.54 10.9 29.0 0.56 10.8 5.0 4.9 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 KEG15443.1 - 0.55 10.6 12.0 2.3 8.6 0.7 4.7 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 KEG15443.1 - 1 7.9 10.4 0.28 9.8 5.4 2.2 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 KEG15443.1 - 1.2 8.0 29.3 0.46 9.3 9.9 4.1 2 1 3 5 5 5 0 Spc7 kinetochore protein DUF16 PF01519.16 KEG15443.1 - 1.2 9.7 9.2 0.76 10.3 1.3 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4530 PF15039.6 KEG15443.1 - 1.4 9.1 8.0 0.11 12.7 0.7 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4530) Fez1 PF06818.15 KEG15443.1 - 1.5 9.3 23.0 1.3e+02 2.9 4.4 3.5 1 1 1 2 2 2 0 Fez1 DUF2663 PF10864.8 KEG15443.1 - 1.5 9.2 3.6 6.3 7.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) FtsX_ECD PF18075.1 KEG15443.1 - 1.6 9.4 4.5 27 5.5 0.4 3.5 1 1 2 3 3 3 0 FtsX extracellular domain Mu-like_Pro PF10123.9 KEG15443.1 - 3.2 7.2 10.3 9.1 5.7 10.3 1.7 1 1 0 1 1 1 0 Mu-like prophage I protein Laminin_II PF06009.12 KEG15443.1 - 3.6 7.6 11.1 1.7 8.7 3.8 3.2 3 1 0 3 3 3 0 Laminin Domain II Nsp1_C PF05064.13 KEG15443.1 - 3.6 7.4 10.8 1.3 8.8 2.2 3.5 2 1 1 3 3 3 0 Nsp1-like C-terminal region SlyX PF04102.12 KEG15443.1 - 4.2 8.1 28.2 5 7.8 0.4 6.9 4 2 4 8 8 8 0 SlyX Spc24 PF08286.11 KEG15443.1 - 4.5 7.6 23.0 58 4.0 0.1 6.0 5 1 0 5 5 5 0 Spc24 subunit of Ndc80 DUF641 PF04859.12 KEG15443.1 - 7.7 6.9 21.3 11 6.4 0.5 4.6 5 0 0 5 5 5 0 Plant protein of unknown function (DUF641) Swi5 PF07061.11 KEG15443.1 - 7.9 6.6 17.3 29 4.8 0.1 5.7 5 2 1 6 6 6 0 Swi5 PIN_8 PF18476.1 KEG15443.1 - 8.1 6.2 8.3 20 4.9 0.6 3.0 2 1 0 3 3 3 0 PIN like domain TolA_bind_tri PF16331.5 KEG15443.1 - 9.1 6.4 29.9 1.7 8.8 0.1 5.9 4 2 2 6 6 6 0 TolA binding protein trimerisation ADIP PF11559.8 KEG15444.1 - 0.059 13.5 2.8 0.11 12.6 2.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_12 PF13424.6 KEG15445.1 - 0.0086 16.3 2.1 2.5 8.5 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat STAT1_TAZ2bind PF12162.8 KEG15445.1 - 0.083 12.5 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain DUF3856 PF12968.7 KEG15445.1 - 0.13 12.4 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) PX PF00787.24 KEG15446.1 - 1e-09 38.4 0.1 3.2e-09 36.8 0.1 1.9 2 0 0 2 2 2 1 PX domain HIP1_clath_bdg PF16515.5 KEG15446.1 - 0.0042 17.7 2.1 0.0086 16.7 0.1 2.4 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF723 PF05265.13 KEG15447.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) EMC1_C PF07774.13 KEG15448.1 - 4.4e-46 157.3 0.0 1.8e-45 155.2 0.0 2.0 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KEG15448.1 - 7.4e-09 35.5 9.1 0.0093 15.6 0.2 3.9 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.21 KEG15448.1 - 3.6e-05 23.5 0.0 1 9.4 0.0 4.4 4 0 0 4 4 4 2 PQQ enzyme repeat Peptidase_S8 PF00082.22 KEG15448.1 - 0.15 11.3 2.0 3.7 6.7 0.3 2.4 2 0 0 2 2 2 0 Subtilase family PQQ_3 PF13570.6 KEG15448.1 - 1.1 9.8 9.0 23 5.6 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain CDC24_OB3 PF17244.2 KEG15450.1 - 0.00086 19.1 0.0 0.0057 16.4 0.0 2.1 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 Rep-A_N PF04057.12 KEG15450.1 - 0.0029 17.6 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain Rep_fac-A_C PF08646.10 KEG15450.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KEG15450.1 - 0.024 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Replication protein A OB domain zf-dskA_traR PF01258.17 KEG15450.1 - 0.034 14.1 1.4 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger AAA_6 PF12774.7 KEG15451.1 - 1.4e-128 428.5 0.0 1.4e-126 421.9 0.0 3.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KEG15451.1 - 2.3e-107 359.6 0.4 2.3e-107 359.6 0.4 5.1 4 2 1 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KEG15451.1 - 1.4e-62 210.7 2.2 1.8e-61 207.1 0.3 3.8 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KEG15451.1 - 5.3e-46 157.0 6.2 1e-43 149.5 0.0 4.4 5 0 0 5 5 3 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 KEG15451.1 - 1.2e-35 122.6 0.1 6.7e-21 74.7 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEG15451.1 - 8e-33 113.5 1.7 9e-28 97.0 0.0 5.2 6 0 0 6 6 5 2 P-loop containing dynein motor region MT PF12777.7 KEG15451.1 - 3.6e-32 111.7 15.1 2e-31 109.3 13.2 2.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 KEG15451.1 - 8.3e-32 110.5 0.1 8.3e-32 110.5 0.1 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.15 KEG15451.1 - 6.4e-31 106.9 0.0 3e-29 101.5 0.0 3.6 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KEG15451.1 - 6.3e-30 104.2 0.0 1.4e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 KEG15451.1 - 6.2e-27 94.6 0.0 6.2e-27 94.6 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 KEG15451.1 - 6.4e-15 56.0 0.4 0.00014 22.3 0.0 6.2 5 1 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 KEG15451.1 - 1e-12 48.6 0.5 0.049 14.1 0.0 5.6 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEG15451.1 - 2.2e-09 37.7 0.6 0.0033 17.7 0.0 4.8 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 KEG15451.1 - 5.3e-08 32.8 0.1 0.0072 16.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KEG15451.1 - 1e-05 25.8 0.1 1.7 8.9 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 KEG15451.1 - 1.4e-05 24.9 0.3 0.12 12.1 0.0 4.0 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 KEG15451.1 - 1.5e-05 25.3 0.0 4.7 7.7 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 KEG15451.1 - 6e-05 23.2 0.2 0.49 10.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEG15451.1 - 0.00011 22.1 0.8 0.0088 16.0 0.0 3.7 4 0 0 4 4 3 1 RsgA GTPase AAA_14 PF13173.6 KEG15451.1 - 0.00027 21.0 0.0 0.1 12.6 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KEG15451.1 - 0.0003 20.4 0.1 1.7 8.1 0.0 3.7 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 KEG15451.1 - 0.00034 19.8 0.0 0.09 11.8 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein CbiA PF01656.23 KEG15451.1 - 0.00041 20.4 0.0 2.1 8.4 0.0 4.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_lid_7 PF17867.1 KEG15451.1 - 0.00054 20.1 0.0 0.0084 16.3 0.0 3.0 2 0 0 2 2 2 1 Midasin AAA lid domain ABC_tran PF00005.27 KEG15451.1 - 0.00084 19.9 10.9 0.023 15.2 0.0 4.7 5 0 0 5 5 3 2 ABC transporter Rad17 PF03215.15 KEG15451.1 - 0.00093 19.2 0.1 5.7 6.8 0.0 3.9 3 0 0 3 3 3 0 Rad17 P-loop domain NACHT PF05729.12 KEG15451.1 - 0.0012 18.8 5.1 0.081 12.8 0.0 3.6 4 0 0 4 4 3 1 NACHT domain TsaE PF02367.17 KEG15451.1 - 0.0016 18.5 0.0 0.36 10.8 0.0 3.6 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 KEG15451.1 - 0.0027 17.6 0.0 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KEG15451.1 - 0.0034 17.1 0.0 0.66 9.7 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein Roc PF08477.13 KEG15451.1 - 0.0054 16.9 0.8 1.1 9.5 0.1 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KEG15451.1 - 0.0077 16.8 7.2 0.66 10.5 0.0 5.4 6 0 0 6 6 4 1 AAA domain SRPRB PF09439.10 KEG15451.1 - 0.0092 15.4 4.3 0.13 11.7 0.0 3.5 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_PrkA PF08298.11 KEG15451.1 - 0.0099 14.8 0.0 0.084 11.8 0.0 2.4 3 0 0 3 3 3 1 PrkA AAA domain AAA_29 PF13555.6 KEG15451.1 - 0.012 15.4 0.0 0.37 10.6 0.0 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEG15451.1 - 0.022 14.0 0.0 0.54 9.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin NB-ARC PF00931.22 KEG15451.1 - 0.026 13.7 4.6 1.2 8.2 0.1 4.3 4 0 0 4 4 4 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KEG15451.1 - 0.028 13.8 0.1 27 4.0 0.0 3.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 KEG15451.1 - 0.033 13.9 0.2 5.7 6.6 0.1 3.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KEG15451.1 - 0.038 13.9 1.9 13 5.7 0.0 4.4 4 0 0 4 4 3 0 NTPase Mg_chelatase PF01078.21 KEG15451.1 - 0.039 13.3 0.1 5 6.5 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 KEG15451.1 - 0.091 12.3 4.0 6.2 6.4 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KEG15451.1 - 0.14 11.9 0.8 17 5.1 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KEG15451.1 - 0.63 10.5 43.0 7.5 7.0 0.0 7.6 7 0 0 7 7 7 0 AAA domain Guanylate_kin PF00625.21 KEG15451.1 - 1.3 8.6 8.6 1.7 8.3 0.0 3.8 4 0 0 4 4 2 0 Guanylate kinase DUF1612 PF07756.12 KEG15451.1 - 2.1 8.6 8.1 5.3 7.3 0.1 4.1 4 0 0 4 4 3 0 Protein of unknown function (DUF1612) ATPase_2 PF01637.18 KEG15451.1 - 8.4 6.2 16.0 0.98 9.3 0.0 4.4 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea zf-CCHC_3 PF13917.6 KEG15452.1 - 2.7e-16 59.2 1.4 2.7e-16 59.2 1.4 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KEG15452.1 - 0.069 13.3 0.4 0.1 12.7 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Fam20C PF06702.12 KEG15453.1 - 1.2e-06 28.5 0.1 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 PI3_PI4_kinase PF00454.27 KEG15453.1 - 0.039 13.8 0.1 0.071 12.9 0.1 1.4 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DUF1180 PF06679.12 KEG15453.1 - 0.07 13.5 0.4 0.11 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Metallophos PF00149.28 KEG15454.1 - 4.1e-36 125.4 0.0 5.8e-20 72.7 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Amastin PF07344.11 KEG15454.1 - 1.3 8.9 7.0 1.2 9.0 1.0 2.8 2 1 1 3 3 3 0 Amastin surface glycoprotein Opiods_neuropep PF01160.18 KEG15454.1 - 1.6 8.9 7.9 6.2 7.0 0.1 2.6 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide Toprim PF01751.22 KEG15457.1 - 0.054 13.7 0.0 0.067 13.4 0.0 1.1 1 0 0 1 1 1 0 Toprim domain FHA PF00498.26 KEG15458.1 - 6.7e-07 29.6 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 KEG15458.1 - 9.3e-05 22.7 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KEG15458.1 - 0.0087 15.9 0.0 0.079 12.8 0.0 2.3 1 1 1 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KEG15458.1 - 0.19 11.7 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain Leg1 PF05612.12 KEG15459.1 - 0.019 14.1 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Leg1 DUF3619 PF12279.8 KEG15459.1 - 0.72 10.2 4.5 4.3 7.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) Kinesin PF00225.23 KEG15460.1 - 6.1e-107 357.4 0.6 9.4e-107 356.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG15460.1 - 1.4e-20 73.8 0.6 3.5e-20 72.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Pex24p PF06398.11 KEG15460.1 - 3.5e-07 29.5 0.5 6.2e-07 28.7 0.5 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Spc7 PF08317.11 KEG15460.1 - 0.027 13.4 22.2 0.048 12.5 22.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 KEG15460.1 - 0.077 11.6 9.7 0.13 10.8 9.7 1.3 1 0 0 1 1 1 0 AAA domain Herpes_UL6 PF01763.16 KEG15460.1 - 0.18 10.3 4.1 0.22 10.0 3.3 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like Spc29 PF17082.5 KEG15460.1 - 0.22 11.3 5.0 0.46 10.3 5.0 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 COG5 PF10392.9 KEG15460.1 - 0.32 11.2 10.5 0.12 12.5 0.6 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Prominin PF05478.11 KEG15460.1 - 0.77 7.6 10.0 1.2 7.0 10.0 1.2 1 0 0 1 1 1 0 Prominin Cnn_1N PF07989.11 KEG15460.1 - 0.86 9.8 13.2 4 7.7 12.3 2.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 KEG15460.1 - 0.96 8.5 15.6 1.7 7.7 15.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 KEG15460.1 - 1.1 9.6 14.2 2.1 8.7 12.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KEG15460.1 - 1.7 7.9 9.8 3.1 7.1 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 KEG15460.1 - 2.2 8.5 10.7 4.1 7.7 10.7 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Kinesin_assoc PF16183.5 KEG15460.1 - 3.1 7.9 11.3 5.1 7.2 0.9 2.7 1 1 1 2 2 2 0 Kinesin-associated TMEM192 PF14802.6 KEG15460.1 - 3.2 6.8 4.7 7 5.7 4.7 1.5 1 0 0 1 1 1 0 TMEM192 family CREPT PF16566.5 KEG15460.1 - 4.4 7.5 15.5 9.3 6.4 15.5 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Cullin_binding PF03556.15 KEG15461.1 - 3.1e-19 69.6 3.7 4.3e-19 69.1 3.7 1.2 1 0 0 1 1 1 1 Cullin binding LRR_4 PF12799.7 KEG15462.1 - 6.5e-16 58.2 6.2 3.9e-06 27.1 1.6 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KEG15462.1 - 4.6e-12 45.8 2.6 5.9e-12 45.4 0.6 2.2 2 1 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KEG15462.1 - 2.8e-11 43.0 12.3 5.4e-06 26.1 4.4 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KEG15462.1 - 0.39 10.9 11.3 14 6.0 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KEG15462.1 - 0.76 10.6 9.5 26 5.9 0.1 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Cyclin PF08613.11 KEG15463.1 - 1.1e-22 81.1 0.8 2e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KEG15463.1 - 4.2e-07 29.7 0.0 8.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF773 PF05600.12 KEG15465.1 - 2.8e-19 69.3 1.3 2.7e-11 42.9 0.5 3.4 1 1 2 3 3 3 3 CDK5 regulatory subunit-associated protein 3 DUF3450 PF11932.8 KEG15465.1 - 0.039 13.2 4.5 0.4 9.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SAM_2 PF07647.17 KEG15465.1 - 0.15 12.2 0.2 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HsbA PF12296.8 KEG15465.1 - 0.2 12.1 2.9 1.7 9.1 0.0 2.8 2 1 1 3 3 3 0 Hydrophobic surface binding protein A CorA PF01544.18 KEG15465.1 - 0.38 10.0 3.8 1.4 8.2 0.8 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein CHASE3 PF05227.13 KEG15465.1 - 4.5 7.2 12.9 1.7 8.5 4.7 2.4 2 0 0 2 2 2 0 CHASE3 domain ATP-synt_DE_N PF02823.16 KEG15466.1 - 7.7e-13 48.2 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_S11 PF00411.19 KEG15467.1 - 1.3e-47 160.8 1.0 1.6e-47 160.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pkinase PF00069.25 KEG15468.1 - 8.7e-36 123.6 0.0 5e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15468.1 - 1.1e-08 34.7 0.0 4.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase zf-CCCH PF00642.24 KEG15469.1 - 0.0035 17.2 0.6 0.006 16.5 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CENP-K PF11802.8 KEG15469.1 - 0.0083 15.7 3.3 0.011 15.3 3.3 1.1 1 0 0 1 1 1 1 Centromere-associated protein K zf_CCCH_4 PF18345.1 KEG15469.1 - 0.16 12.1 3.8 0.29 11.3 0.8 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 KEG15469.1 - 0.2 12.2 1.8 0.38 11.3 1.8 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Mago_nashi PF02792.14 KEG15470.1 - 2.8e-61 205.8 0.1 3.2e-61 205.6 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein p450 PF00067.22 KEG15471.1 - 6.5e-47 160.3 0.0 8.4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RF-1 PF00472.20 KEG15472.1 - 9.7e-09 35.2 0.1 1.9e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 RF-1 domain Rhodanese PF00581.20 KEG15473.1 - 0.00066 20.2 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain S-AdoMet_synt_C PF02773.16 KEG15474.1 - 2e-67 225.5 0.0 3.1e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KEG15474.1 - 6.6e-44 149.0 0.0 8.2e-43 145.5 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KEG15474.1 - 1.4e-39 134.7 0.1 3.2e-39 133.6 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PDZ_2 PF13180.6 KEG15475.1 - 0.00065 20.0 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KEG15475.1 - 0.0015 18.3 0.0 0.0064 16.3 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KEG15475.1 - 0.025 14.9 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Tricorn_PDZ PF14685.6 KEG15475.1 - 0.2 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain zf-MIZ PF02891.20 KEG15476.1 - 3.4e-17 61.9 8.6 5.5e-17 61.2 8.6 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PWWP PF00855.17 KEG15476.1 - 1.9e-06 28.1 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PWWP domain zf-Nse PF11789.8 KEG15476.1 - 0.0021 17.8 2.8 0.0041 16.9 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.25 KEG15478.1 - 2.1e-24 86.3 0.0 2.6e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15478.1 - 8.1e-13 48.2 0.0 9.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEG15478.1 - 2.1e-08 33.4 0.1 2.8e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Yippee-Mis18 PF03226.14 KEG15479.1 - 5.9e-14 52.2 0.1 7.6e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KEG15479.1 - 4.3e-05 23.7 0.2 5.9e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I Endonuclease_7 PF02945.15 KEG15479.1 - 0.055 13.4 2.2 0.082 12.8 2.2 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII TPR_11 PF13414.6 KEG15480.1 - 0.0003 20.4 0.2 0.072 12.8 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TTC5_OB PF16669.5 KEG15480.1 - 0.00059 19.5 0.0 0.00091 18.9 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_17 PF13431.6 KEG15480.1 - 0.00061 20.0 0.1 2.7 8.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEG15480.1 - 0.002 18.7 8.6 0.48 11.1 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEG15480.1 - 0.016 15.2 5.2 4.2 7.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEG15480.1 - 0.067 14.0 8.4 3.6 8.7 0.2 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEG15480.1 - 0.13 12.5 6.5 0.37 11.0 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA_int_endo PF01974.17 KEG15481.1 - 0.01 15.9 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain DNA_ligase_A_M PF01068.21 KEG15482.1 - 1.8e-60 204.1 0.0 1e-59 201.7 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEG15482.1 - 5.4e-33 114.8 0.0 3.3e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KEG15482.1 - 8.4e-25 87.3 0.0 2.6e-24 85.7 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KEG15482.1 - 9.6e-05 22.8 0.1 0.00019 21.8 0.1 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KEG15482.1 - 0.096 12.7 4.4 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 DNA ligase OB-like domain MKT1_C PF12246.8 KEG15483.1 - 4.5e-27 94.8 0.0 7.2e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KEG15483.1 - 8.4e-11 42.1 0.1 2.8e-10 40.4 0.1 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Tcp11 PF05794.13 KEG15484.1 - 5.7e-19 68.5 0.3 2e-18 66.7 0.0 2.0 1 1 1 2 2 2 1 T-complex protein 11 ANAPC_CDC26 PF10471.9 KEG15484.1 - 0.21 12.4 17.5 0.78 10.6 17.5 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Dynein_heavy PF03028.15 KEG15485.1 - 3.1e-10 40.2 0.0 6.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 KEG15485.1 - 4.2e-08 33.7 6.3 1.1 10.3 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEG15485.1 - 0.07 12.1 0.6 2.5 7.0 0.0 2.8 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-tcix PF14952.6 KEG15486.1 - 0.94 9.2 11.9 0.55 9.9 4.2 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding HypA PF01155.19 KEG15486.1 - 2 8.5 6.6 4.2 7.4 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Mss51 PF13824.6 KEG15486.1 - 2.2 8.4 5.7 6.2 7.0 1.1 2.5 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CAS_CSE1 PF03378.15 KEG15487.1 - 3.1e-85 286.3 0.1 7.6e-85 285.0 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KEG15487.1 - 9.9e-60 202.3 0.0 1.4e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Cse1 Adaptin_N PF01602.20 KEG15487.1 - 2.6e-05 23.0 2.2 0.025 13.1 0.2 2.5 2 0 0 2 2 2 2 Adaptin N terminal region IBN_N PF03810.19 KEG15487.1 - 0.00017 21.4 0.0 0.0015 18.4 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KEG15487.1 - 0.00079 19.5 0.8 0.037 14.1 0.2 3.8 3 1 1 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.6 KEG15487.1 - 0.0031 17.9 0.5 6.8 7.2 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Telomere_reg-2 PF10193.9 KEG15487.1 - 0.061 13.8 0.1 24 5.4 0.0 3.8 3 0 0 3 3 3 0 Telomere length regulation protein AI-2E_transport PF01594.16 KEG15487.1 - 0.13 11.4 2.6 0.87 8.7 0.7 2.5 3 0 0 3 3 3 0 AI-2E family transporter PGK PF00162.19 KEG15488.1 - 2.4e-132 441.4 0.0 2.9e-132 441.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.25 KEG15488.1 - 5.3e-07 29.6 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEG15488.1 - 4.1e-05 23.8 0.0 0.00016 21.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KEG15488.1 - 5.7e-05 23.0 0.1 0.0002 21.3 0.1 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KEG15488.1 - 0.00047 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold EF-hand_7 PF13499.6 KEG15489.1 - 1.1e-31 109.1 19.3 3.1e-08 33.9 0.7 5.7 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 KEG15489.1 - 4.7e-29 97.7 16.3 0.00012 21.3 0.1 8.7 8 0 0 8 8 8 6 EF hand EF-hand_6 PF13405.6 KEG15489.1 - 1.2e-25 87.2 14.4 0.00022 20.9 0.1 9.8 9 0 0 9 9 9 4 EF-hand domain EF-hand_8 PF13833.6 KEG15489.1 - 2.3e-22 78.6 7.7 0.0012 18.6 0.0 9.9 10 0 0 10 10 10 4 EF-hand domain pair EF-hand_5 PF13202.6 KEG15489.1 - 1.6e-19 68.4 11.1 0.0001 21.6 0.1 7.8 9 0 0 9 9 8 4 EF hand SPARC_Ca_bdg PF10591.9 KEG15489.1 - 2e-05 24.9 10.4 0.056 13.8 0.0 5.6 5 1 0 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region FGAR-AT_linker PF18072.1 KEG15489.1 - 0.0021 18.6 0.3 29 5.3 0.0 4.5 4 0 0 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain CDC45 PF02724.14 KEG15489.1 - 0.048 11.9 8.2 0.076 11.3 8.2 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3349 PF11829.8 KEG15489.1 - 0.06 14.1 12.2 8.4 7.2 0.1 5.2 6 0 0 6 6 4 0 Protein of unknown function (DUF3349) CobT PF06213.12 KEG15489.1 - 0.099 12.0 22.9 0.21 10.9 22.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CUE PF02845.16 KEG15489.1 - 0.19 11.5 1.4 4.2 7.2 0.0 3.8 4 0 0 4 4 4 0 CUE domain TERB2 PF15101.6 KEG15489.1 - 0.25 11.3 6.8 0.52 10.3 6.8 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ZIP4_domain PF18292.1 KEG15489.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.7 3 0 0 3 3 2 0 Zinc transporter ZIP4 domain DDHD PF02862.17 KEG15489.1 - 0.32 11.1 4.8 0.6 10.2 4.8 1.5 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 KEG15489.1 - 0.44 10.3 13.9 0.77 9.5 13.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KEG15489.1 - 1.1 7.9 13.9 1.5 7.5 13.9 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 KEG15489.1 - 1.1 9.4 11.3 2 8.6 11.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 KEG15489.1 - 3 7.0 5.8 4.4 6.4 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.11 KEG15489.1 - 4 7.4 11.4 7.3 6.6 11.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ALMT PF11744.8 KEG15489.1 - 4.1 6.1 13.5 1.2 7.9 10.3 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 KEG15489.1 - 4.4 7.3 7.7 8 6.4 7.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM10 PF12519.8 KEG15489.1 - 5.6 5.7 8.5 8.5 5.1 8.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CCDC53 PF10152.9 KEG15489.1 - 7.1 7.0 16.5 22 5.4 16.5 1.9 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3464 PF11947.8 KEG15489.1 - 7.2 6.3 11.7 17 5.1 11.7 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CCSAP PF15748.5 KEG15489.1 - 9.7 6.3 21.6 16 5.5 21.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated KIF1B PF12423.8 KEG15490.1 - 0.79 10.2 6.9 3.2 8.3 0.8 3.0 2 0 0 2 2 2 0 Kinesin protein 1B Ribosomal_L6 PF00347.23 KEG15492.1 - 1.3e-26 93.1 3.8 6.1e-15 55.7 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF1488 PF07369.11 KEG15493.1 - 0.19 11.7 0.3 0.19 11.7 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) TFIIA PF03153.13 KEG15494.1 - 2.8 7.9 23.0 4.8 7.1 23.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MORN PF02493.20 KEG15495.1 - 1.4e-95 307.8 111.1 7.7e-10 38.1 2.9 15.1 15 0 0 15 15 15 15 MORN repeat B-block_TFIIIC PF04182.12 KEG15495.1 - 0.31 11.2 2.2 6.9 6.9 0.0 3.8 4 1 1 5 5 5 0 B-block binding subunit of TFIIIC AA_permease_2 PF13520.6 KEG15496.1 - 3.7e-44 151.2 35.5 4.5e-44 151.0 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEG15496.1 - 2.1e-33 115.6 30.8 2.6e-33 115.3 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KEG15496.1 - 1.1e-08 35.0 6.5 1.1e-08 35.0 6.5 3.9 4 0 0 4 4 4 1 C-terminus of AA_permease UBA PF00627.31 KEG15497.1 - 1.2e-19 69.8 5.6 4.6e-10 39.2 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KEG15497.1 - 1.6e-15 56.6 4.6 3e-15 55.7 4.6 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KEG15497.1 - 7.1e-10 38.5 0.2 1.1e-09 37.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KEG15497.1 - 1.1e-05 25.1 0.8 2.2e-05 24.2 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KEG15497.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain TPR_2 PF07719.17 KEG15499.1 - 0.025 14.7 0.1 2.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Metallophos PF00149.28 KEG15500.1 - 1.4e-09 38.7 0.1 2.8e-09 37.8 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AA_permease_2 PF13520.6 KEG15501.1 - 0.017 14.0 0.9 0.02 13.7 0.9 1.1 1 0 0 1 1 1 0 Amino acid permease Ank_4 PF13637.6 KEG15502.1 - 1.1e-34 118.3 2.6 2.5e-08 34.3 0.0 6.4 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEG15502.1 - 6.8e-31 106.7 0.6 3e-11 43.7 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEG15502.1 - 5.1e-25 87.2 3.6 8.2e-06 26.0 0.1 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KEG15502.1 - 5.1e-25 86.8 3.5 9.8e-05 22.6 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KEG15502.1 - 8.6e-24 81.0 0.8 7.1e-05 22.9 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat LMBR1 PF04791.16 KEG15502.1 - 2.6 6.9 3.9 2.9 6.7 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Helicase_C PF00271.31 KEG15503.1 - 1.9e-12 47.5 0.2 2.3e-10 40.8 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 KEG15503.1 - 4.9e-12 46.1 0.0 4.9e-12 46.1 0.0 3.1 3 1 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KEG15503.1 - 8.5e-08 32.2 0.0 3.9e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KEG15503.1 - 3.4e-06 27.3 0.2 1.5e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KEG15503.1 - 8.4e-06 26.1 0.7 3.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEG15503.1 - 0.00024 21.5 0.0 0.00085 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEG15503.1 - 0.0029 17.4 0.4 0.0082 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEG15503.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KEG15503.1 - 0.035 14.1 0.0 0.035 14.1 0.0 3.5 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 KEG15503.1 - 0.039 14.5 0.0 0.039 14.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KEG15503.1 - 0.088 13.2 0.0 0.38 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KEG15503.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 0 KaiC tRNA-synt_1c PF00749.21 KEG15504.1 - 3.3e-101 338.3 0.1 4.4e-101 337.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEG15504.1 - 2.4e-37 128.5 0.1 5.1e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KEG15504.1 - 0.0089 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Adaptin_N PF01602.20 KEG15505.1 - 9.9e-96 321.4 4.4 1.3e-95 321.0 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEG15505.1 - 1.3e-17 64.3 5.1 2.1e-16 60.4 0.6 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEG15505.1 - 1.3e-06 28.7 4.8 0.00074 19.9 0.2 4.1 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 KEG15505.1 - 6.7e-05 22.8 9.4 0.077 13.3 0.1 5.0 5 0 0 5 5 4 2 HEAT repeat Pox_Ag35 PF03286.14 KEG15505.1 - 0.0064 16.3 3.8 0.0064 16.3 3.8 3.3 3 1 0 3 3 3 1 Pox virus Ag35 surface protein SDA1 PF05285.12 KEG15505.1 - 0.014 14.8 15.0 0.19 11.2 2.3 2.2 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.6 KEG15505.1 - 0.025 14.2 13.3 0.31 10.7 5.2 2.7 2 0 0 2 2 2 0 FAM176 family Mo25 PF08569.11 KEG15505.1 - 0.039 13.3 0.6 0.24 10.7 0.1 2.2 2 0 0 2 2 2 0 Mo25-like RasGEF_N_2 PF14663.6 KEG15505.1 - 0.057 13.8 1.6 8.7 6.8 0.1 2.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 KEG15505.1 - 0.08 13.5 4.0 13 6.4 0.1 4.5 4 1 1 5 5 5 0 HEAT-like repeat TLP-20 PF06088.11 KEG15505.1 - 0.084 12.8 10.0 0.38 10.6 1.8 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Arm PF00514.23 KEG15505.1 - 0.11 12.6 6.2 0.33 11.1 0.4 3.1 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat SPX PF03105.19 KEG15505.1 - 0.24 11.3 15.3 0.075 12.9 1.3 2.2 2 0 0 2 2 2 0 SPX domain GCIP PF13324.6 KEG15505.1 - 0.28 10.8 6.9 0.43 10.2 0.6 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF913 PF06025.12 KEG15505.1 - 1.1 8.1 8.3 0.32 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 KEG15505.1 - 1.6 9.1 20.9 3.7 8.0 1.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 KEG15505.1 - 2.2 6.7 11.5 0.02 13.4 0.6 2.4 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 SpoIIIAH PF12685.7 KEG15505.1 - 2.6 7.8 13.2 0.19 11.6 1.4 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein Sigma70_ner PF04546.13 KEG15505.1 - 3.3 7.5 13.7 0.18 11.7 2.1 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 KEG15505.1 - 3.6 5.7 20.5 2.8 6.0 3.1 2.2 2 0 0 2 2 2 0 Nop14-like family Exo_endo_phos PF03372.23 KEG15506.1 - 5.8e-13 48.9 0.0 2.2e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HEAT PF02985.22 KEG15507.1 - 2e-05 24.4 9.1 1.4 9.4 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat IFRD PF05004.13 KEG15507.1 - 0.00028 20.1 2.5 0.031 13.4 1.6 3.2 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) DUF1657 PF07870.11 KEG15508.1 - 0.11 12.4 1.8 0.27 11.2 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) GST_C_2 PF13410.6 KEG15511.1 - 2.7e-06 27.3 0.0 5.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEG15511.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pox_Ag35 PF03286.14 KEG15511.1 - 0.065 13.0 2.0 0.12 12.2 2.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF512 PF04459.12 KEG15511.1 - 0.084 12.1 0.0 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF512) COG2 PF06148.11 KEG15512.1 - 2.3e-42 144.3 2.5 2.3e-42 144.3 2.5 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 KEG15512.1 - 2.2e-31 108.9 0.6 4.6e-29 101.4 0.0 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3510) Med21 PF11221.8 KEG15512.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.2 4 0 0 4 4 4 0 Subunit 21 of Mediator complex KIX PF02172.16 KEG15513.1 - 0.077 13.3 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 KIX domain IGF2_C PF08365.11 KEG15513.1 - 0.51 10.4 5.0 0.21 11.7 1.1 2.3 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide MIF4G PF02854.19 KEG15514.1 - 5e-28 98.2 1.2 5e-28 98.2 1.2 1.8 2 0 0 2 2 1 1 MIF4G domain CobT PF06213.12 KEG15514.1 - 0.00023 20.7 10.0 0.00023 20.7 10.0 1.8 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT EPL1 PF10513.9 KEG15514.1 - 0.00041 20.8 9.1 0.00041 20.8 9.1 2.4 3 0 0 3 3 2 1 Enhancer of polycomb-like DUF4638 PF15472.6 KEG15514.1 - 0.093 12.4 8.9 0.1 12.3 7.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) PAT1 PF09770.9 KEG15514.1 - 0.1 10.9 16.5 0.16 10.2 16.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hydin_ADK PF17213.3 KEG15514.1 - 0.3 11.3 6.7 0.61 10.3 4.1 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Zip PF02535.22 KEG15514.1 - 0.34 10.1 9.7 0.64 9.2 9.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 KEG15514.1 - 0.37 8.9 8.6 2.6 6.1 6.4 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KEG15514.1 - 0.44 9.3 10.4 0.82 8.4 10.4 1.4 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 KEG15514.1 - 0.63 9.4 14.7 1.4 8.2 14.7 1.5 1 0 0 1 1 1 0 FAM76 protein Pannexin_like PF12534.8 KEG15514.1 - 1.7 7.7 7.7 20 4.1 5.0 2.2 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Spt20 PF12090.8 KEG15514.1 - 2.4 7.7 27.6 6.5 6.3 27.6 1.7 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 KEG15514.1 - 3 7.3 17.4 0.12 11.9 8.6 2.5 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist PRIMA1 PF16101.5 KEG15514.1 - 5.2 7.1 10.5 0.38 10.8 5.1 1.9 2 0 0 2 2 1 0 Proline-rich membrane anchor 1 TERB2 PF15101.6 KEG15514.1 - 10 6.1 16.8 19 5.2 14.8 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Elf1 PF05129.13 KEG15515.1 - 0.022 14.8 0.7 0.022 14.8 0.7 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like RecR PF02132.15 KEG15515.1 - 0.069 12.7 4.4 0.13 11.9 0.7 2.5 2 0 0 2 2 2 0 RecR protein C1_2 PF03107.16 KEG15515.1 - 1.1 9.7 6.3 10 6.6 0.6 2.7 2 1 0 2 2 2 0 C1 domain Peptidase_M8 PF01457.16 KEG15516.1 - 7.1e-90 302.2 0.0 7.9e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin UPF0052 PF01933.18 KEG15516.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0052 Peptidase_S10 PF00450.22 KEG15519.1 - 1.7e-113 380.2 0.5 2.2e-113 379.8 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KEG15519.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cpn60_TCP1 PF00118.24 KEG15520.1 - 7.1e-147 490.0 11.3 8e-147 489.8 11.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CMS1 PF14617.6 KEG15520.1 - 0.033 13.5 0.3 0.33 10.2 0.2 2.3 1 1 1 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Colicin PF01024.19 KEG15520.1 - 0.067 13.1 1.6 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Colicin pore forming domain Pkinase PF00069.25 KEG15521.1 - 1.1e-73 247.9 0.0 1.3e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEG15521.1 - 8.5e-31 107.2 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEG15521.1 - 0.026 14.5 0.2 0.81 9.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEG15521.1 - 0.14 11.0 0.0 1.1 8.2 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Ribosom_S12_S23 PF00164.25 KEG15522.1 - 6.3e-48 161.1 0.6 6.3e-48 161.1 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Ribosomal_L6 PF00347.23 KEG15523.1 - 1e-26 93.4 3.8 4.8e-15 56.0 0.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 HSP20 PF00011.21 KEG15523.1 - 0.045 13.9 0.5 0.25 11.5 0.0 2.3 2 1 0 2 2 2 0 Hsp20/alpha crystallin family Kinesin PF00225.23 KEG15524.1 - 2.3e-81 273.3 0.2 2.3e-81 273.3 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEG15524.1 - 2.3e-12 47.1 0.0 1.2e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Ax_dynein_light PF10211.9 KEG15527.1 - 8.5e-55 185.6 3.2 1e-54 185.4 3.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ThiD2 PF17792.1 KEG15527.1 - 0.0036 17.8 1.0 0.0075 16.7 1.0 1.5 1 0 0 1 1 1 1 ThiD2 family ZapB PF06005.12 KEG15527.1 - 0.032 14.7 11.1 0.082 13.4 8.7 2.3 2 0 0 2 2 2 0 Cell division protein ZapB UPF0449 PF15136.6 KEG15527.1 - 0.11 12.9 3.0 0.42 11.1 0.9 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Spc24 PF08286.11 KEG15527.1 - 1.9 8.8 4.3 3.8 7.8 4.3 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Tubulin PF00091.25 KEG15528.1 - 3.2e-61 207.0 0.0 4.5e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEG15528.1 - 4.5e-26 91.5 0.0 9.1e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KEG15528.1 - 8.1e-05 22.0 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.9 KEG15528.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KEG15528.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Bombesin PF02044.17 KEG15528.1 - 0.15 12.2 1.2 0.36 11.0 1.2 1.6 1 0 0 1 1 1 0 Bombesin-like peptide UPF0449 PF15136.6 KEG15529.1 - 0.029 14.9 0.4 0.029 14.9 0.4 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 YabA PF06156.13 KEG15529.1 - 0.76 10.4 10.7 0.99 10.1 1.2 3.1 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KEG15529.1 - 0.8 9.8 9.0 1.1 9.4 4.4 3.2 1 1 1 2 2 2 0 bZIP transcription factor Synaphin PF05835.12 KEG15530.1 - 0.044 14.1 2.3 0.054 13.8 2.3 1.1 1 0 0 1 1 1 0 Synaphin protein Clathrin PF00637.20 KEG15531.1 - 8.1e-11 42.0 26.5 0.054 13.4 0.0 10.7 7 3 5 12 12 12 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KEG15531.1 - 8.7e-08 32.4 0.6 1 9.7 0.0 5.0 3 1 2 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG15531.1 - 9.4e-06 26.3 6.1 0.23 12.4 0.1 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KEG15531.1 - 0.00011 21.4 11.0 0.011 14.8 0.8 5.7 4 2 0 5 5 5 1 Coatomer WD associated region PPR PF01535.20 KEG15531.1 - 0.0017 18.5 11.1 0.39 11.1 0.3 6.8 7 0 0 7 7 5 1 PPR repeat TPR_7 PF13176.6 KEG15531.1 - 0.0043 17.0 28.3 6.8 7.0 0.0 13.1 15 1 0 15 15 15 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEG15531.1 - 0.025 15.4 28.2 75 4.6 0.0 13.3 12 4 4 16 16 14 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEG15531.1 - 0.026 14.4 35.0 12 5.9 0.0 11.7 11 2 2 13 13 12 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEG15531.1 - 0.029 14.6 17.2 1.2 9.4 0.1 8.0 6 2 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Utp13 PF08625.11 KEG15531.1 - 0.032 14.1 8.3 0.33 10.8 0.0 5.5 6 1 1 7 7 6 0 Utp13 specific WD40 associated domain PTAC PF06130.12 KEG15531.1 - 0.12 12.5 0.1 0.39 10.9 0.1 1.9 1 0 0 1 1 1 0 Phosphate propanoyltransferase TPR_12 PF13424.6 KEG15531.1 - 0.18 12.1 0.1 0.18 12.1 0.1 8.5 9 1 0 10 10 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEG15531.1 - 0.54 10.0 9.5 37 4.1 0.1 6.9 8 0 0 8 8 8 0 TPR repeat Mad3_BUB1_I PF08311.12 KEG15531.1 - 1.1 9.2 14.0 31 4.5 2.0 6.3 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KEG15531.1 - 1.2 9.5 0.0 1.2 9.5 0.0 12.2 13 2 2 15 15 15 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEG15531.1 - 1.4 9.4 23.3 10 6.6 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF410 PF04190.13 KEG15531.1 - 2.1 8.1 10.0 11 5.7 0.1 4.7 4 2 1 5 5 5 0 Protein of unknown function (DUF410) PPR_2 PF13041.6 KEG15531.1 - 4.3 7.6 14.4 0.89 9.8 0.2 6.4 9 0 0 9 9 8 0 PPR repeat family PDCD2_C PF04194.13 KEG15534.1 - 9.3e-32 110.5 0.0 9.3e-32 110.5 0.0 2.2 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain AAA PF00004.29 KEG15535.1 - 7.5e-41 139.6 0.0 1.3e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG15535.1 - 4.9e-11 42.2 0.0 1.7e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KEG15535.1 - 1.7e-08 34.3 0.1 4.7e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KEG15535.1 - 0.0001 22.6 0.1 0.003 17.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEG15535.1 - 0.00023 21.2 0.3 0.0023 17.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KEG15535.1 - 0.00039 19.7 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KEG15535.1 - 0.00043 20.4 0.0 0.00087 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEG15535.1 - 0.00053 20.4 0.1 0.0014 19.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KEG15535.1 - 0.00065 19.5 0.0 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEG15535.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEG15535.1 - 0.0026 17.9 0.0 0.0057 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KEG15535.1 - 0.0026 17.6 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 KEG15535.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEG15535.1 - 0.0033 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KEG15535.1 - 0.004 16.8 0.8 0.16 11.5 0.2 2.5 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 KEG15535.1 - 0.011 15.6 0.0 0.13 12.2 0.0 2.3 2 1 1 3 3 2 0 NACHT domain CPT PF07931.12 KEG15535.1 - 0.013 15.4 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KEG15535.1 - 0.017 15.7 0.0 0.039 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEG15535.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEG15535.1 - 0.025 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KEG15535.1 - 0.04 13.6 0.0 0.99 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEG15535.1 - 0.065 13.5 0.1 0.17 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KEG15535.1 - 0.076 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KEG15535.1 - 0.089 13.2 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF815 PF05673.13 KEG15535.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KEG15535.1 - 0.15 11.2 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 KEG15535.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tmemb_55A PF09788.9 KEG15537.1 - 0.045 12.8 0.1 0.053 12.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A AAA_14 PF13173.6 KEG15539.1 - 0.0045 17.0 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEG15539.1 - 0.044 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain RecA PF00154.21 KEG15539.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ATPase_2 PF01637.18 KEG15539.1 - 0.25 11.2 0.0 0.4 10.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FixQ PF05545.11 KEG15540.1 - 3.7 7.6 8.2 7.2 6.7 0.0 3.9 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ TPR_12 PF13424.6 KEG15541.1 - 0.036 14.3 1.5 1.1 9.6 0.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat YbaB_DNA_bd PF02575.16 KEG15542.1 - 0.0046 17.2 1.8 1.3 9.3 0.1 3.0 4 0 0 4 4 4 2 YbaB/EbfC DNA-binding family Exo_endo_phos PF03372.23 KEG15543.1 - 7.3e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Flexi_CP PF00286.20 KEG15543.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Viral coat protein Methyltransf_25 PF13649.6 KEG15544.1 - 1.8e-08 35.0 0.1 3.4e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEG15544.1 - 2.9e-08 33.6 0.0 4.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEG15544.1 - 4e-05 23.2 0.0 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KEG15544.1 - 4.2e-05 24.1 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEG15544.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KEG15544.1 - 0.0015 19.3 0.0 0.0028 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KEG15544.1 - 0.0059 15.6 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_24 PF13578.6 KEG15544.1 - 0.009 17.0 0.0 0.02 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Big_7 PF17957.1 KEG15544.1 - 0.012 16.3 0.7 1.3 9.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig domain Myotub-related PF06602.14 KEG15545.1 - 2.5e-92 309.5 0.0 6.6e-92 308.2 0.0 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 KEG15545.1 - 1.3e-13 50.8 10.6 4.9e-13 49.0 10.6 2.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KEG15545.1 - 0.025 14.8 5.1 0.066 13.4 5.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 KEG15545.1 - 0.47 10.8 9.1 0.22 11.8 5.4 2.5 2 0 0 2 2 2 0 C1 domain Helicase_C_2 PF13307.6 KEG15546.1 - 1.4e-45 155.5 0.0 3.8e-45 154.1 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KEG15546.1 - 4e-28 98.2 0.9 3.3e-20 72.4 0.0 3.5 3 0 0 3 3 3 2 DEAD_2 ResIII PF04851.15 KEG15546.1 - 0.0047 16.9 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KEG15546.1 - 0.0064 16.3 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 KEG15546.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KEG15546.1 - 0.3 10.8 2.8 6.5 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Arrestin_N PF00339.29 KEG15547.1 - 3.1e-11 43.5 0.1 4.4e-10 39.8 0.1 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEG15547.1 - 0.023 15.1 0.0 1.3 9.5 0.0 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KEG15547.1 - 0.14 11.8 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like BSP PF04450.12 KEG15547.1 - 0.24 11.2 0.4 5.3 6.8 0.4 2.2 1 1 0 1 1 1 0 Peptidase of plants and bacteria DUF1682 PF07946.14 KEG15548.1 - 0.058 12.6 1.5 0.077 12.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ADH_zinc_N PF00107.26 KEG15550.1 - 3.9e-19 68.9 0.0 6.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEG15550.1 - 6.2e-19 69.4 0.0 1.1e-18 68.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEG15550.1 - 9e-09 35.2 1.0 5.1e-08 32.8 0.7 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TSNR_N PF04705.12 KEG15550.1 - 0.009 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Thiostrepton-resistance methylase, N terminus ADH_N_2 PF16884.5 KEG15550.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AAA PF00004.29 KEG15552.1 - 8.3e-44 149.2 0.0 1.7e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEG15552.1 - 1.4e-13 50.4 0.5 1.4e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 KEG15552.1 - 1.4e-06 28.5 0.0 4.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KEG15552.1 - 2.1e-06 27.8 0.1 1.6e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEG15552.1 - 3.7e-06 27.4 0.2 0.0041 17.5 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEG15552.1 - 1.7e-05 25.1 0.3 0.0085 16.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEG15552.1 - 1.7e-05 24.6 0.0 4.9e-05 23.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_ID_OB PF16450.5 KEG15552.1 - 0.00042 20.2 0.4 0.00094 19.1 0.4 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain IstB_IS21 PF01695.17 KEG15552.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KEG15552.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KEG15552.1 - 0.002 17.4 0.0 0.004 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KEG15552.1 - 0.0028 18.2 0.0 0.0093 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEG15552.1 - 0.003 17.1 0.0 0.01 15.4 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KEG15552.1 - 0.005 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEG15552.1 - 0.0066 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 KEG15552.1 - 0.0074 16.2 0.0 0.07 13.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEG15552.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KEG15552.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KEG15552.1 - 0.017 14.8 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KEG15552.1 - 0.022 14.1 2.5 0.33 10.3 0.1 3.0 2 1 1 3 3 3 0 KaiC AAA_24 PF13479.6 KEG15552.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEG15552.1 - 0.031 14.8 0.1 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KEG15552.1 - 0.037 14.2 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KEG15552.1 - 0.04 13.4 0.1 0.11 11.9 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KEG15552.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEG15552.1 - 0.057 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KEG15552.1 - 0.069 13.1 0.2 0.45 10.4 0.0 2.4 2 1 1 3 3 3 0 NACHT domain AAA_25 PF13481.6 KEG15552.1 - 0.082 12.5 0.3 0.59 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEG15552.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TruD PF01142.18 KEG15553.1 - 2.8e-05 23.2 0.0 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) RRM_1 PF00076.22 KEG15554.1 - 2e-15 56.4 0.1 2.1e-07 30.7 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 KEG15554.1 - 0.98 9.0 10.8 0.18 11.4 6.8 1.9 2 0 0 2 2 2 0 Spt20 family FAM76 PF16046.5 KEG15554.1 - 2.4 7.4 6.1 4.3 6.6 6.1 1.3 1 0 0 1 1 1 0 FAM76 protein DSPc PF00782.20 KEG15555.1 - 0.0017 18.1 0.4 0.0067 16.2 0.1 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain MscS_TM PF12794.7 KEG15556.1 - 1.7 7.4 14.9 2.2 7.1 5.1 2.8 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF4199 PF13858.6 KEG15556.1 - 3 8.2 8.6 1.6 9.1 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Ank_2 PF12796.7 KEG15557.1 - 1.5e-30 105.6 0.1 2.9e-12 47.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEG15557.1 - 7.3e-22 75.1 0.9 0.00048 20.4 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KEG15557.1 - 8.4e-22 77.0 1.5 1.8e-07 31.3 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEG15557.1 - 4.9e-19 67.8 0.0 5.2e-05 23.5 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KEG15557.1 - 1.6e-18 66.8 0.4 0.00017 22.0 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DHHC PF01529.20 KEG15557.1 - 1.3e-05 25.3 3.7 1.3e-05 25.3 3.7 3.5 3 1 0 3 3 3 1 DHHC palmitoyltransferase SVIP PF15811.5 KEG15560.1 - 0.047 14.1 0.6 0.17 12.3 0.6 2.0 1 0 0 1 1 1 0 Small VCP/p97-interacting protein TLD PF07534.16 KEG15561.1 - 3.1e-20 72.8 0.0 8.1e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 TLD Ribosomal_60s PF00428.19 KEG15562.1 - 1.2e-23 83.4 7.5 1.5e-23 83.2 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DEC-1_N PF04625.13 KEG15562.1 - 0.12 11.4 1.7 0.11 11.5 1.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.16 KEG15564.1 - 4e-29 101.6 33.9 7.5e-27 94.2 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEG15564.1 - 1.1e-10 40.5 0.0 1.1e-10 40.5 0.0 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Gpr1_Fun34_YaaH PF01184.19 KEG15565.1 - 6.5e-48 163.1 11.0 8.7e-48 162.7 11.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 5TM-5TMR_LYT PF07694.12 KEG15565.1 - 0.91 9.0 17.7 0.069 12.7 12.6 1.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT cNMP_binding PF00027.29 KEG15566.1 - 3.8e-22 78.2 0.0 1.3e-09 37.9 0.0 4.1 3 1 1 4 4 4 3 Cyclic nucleotide-binding domain DUF3349 PF11829.8 KEG15567.1 - 0.015 16.0 0.1 0.17 12.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) RINGv PF12906.7 KEG15569.1 - 0.0038 17.3 1.4 0.0038 17.3 1.4 2.6 2 0 0 2 2 2 1 RING-variant domain Ninjurin PF04923.12 KEG15569.1 - 0.27 11.2 1.5 1.3 9.0 1.5 2.3 1 0 0 1 1 1 0 Ninjurin PIN_4 PF13638.6 KEG15570.1 - 5.3e-08 33.2 0.0 1.5e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 PIN domain HECT PF00632.25 KEG15571.1 - 3.2e-34 118.8 0.0 1.8e-33 116.4 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 KEG15571.1 - 6.7e-24 84.3 0.3 1.9e-06 28.0 0.0 4.8 4 0 0 4 4 4 4 SPRY domain BT1 PF03092.16 KEG15571.1 - 0.055 11.7 0.0 0.093 10.9 0.0 1.2 1 0 0 1 1 1 0 BT1 family zf-UBR PF02207.20 KEG15571.1 - 0.058 13.6 6.8 0.24 11.6 6.8 2.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) ZZ PF00569.17 KEG15571.1 - 0.1 12.5 15.0 0.018 14.9 10.6 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type ERCC3_RAD25_C PF16203.5 KEG15572.1 - 7.1e-69 231.7 0.0 1.2e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEG15572.1 - 1.3e-15 57.8 0.0 2.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_3 PF13625.6 KEG15572.1 - 4.4e-14 52.7 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 KEG15572.1 - 5.3e-11 42.8 0.0 1.4e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEG15572.1 - 3.4e-05 22.8 0.0 5.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ribosomal_L2_C PF03947.18 KEG15573.1 - 5.9e-43 146.1 2.9 5.9e-43 146.1 2.9 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KEG15573.1 - 1.9e-12 46.9 0.0 5.5e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_C54 PF03416.19 KEG15574.1 - 1e-52 179.3 0.0 1.3e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Myosin_head PF00063.21 KEG15576.1 - 3.1e-175 584.2 4.2 5.3e-175 583.5 4.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.31 KEG15576.1 - 5e-05 23.1 0.0 0.46 10.4 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain CUE PF02845.16 KEG15576.1 - 0.029 14.1 0.0 42 4.0 0.0 3.7 3 0 0 3 3 3 0 CUE domain AAA_22 PF13401.6 KEG15576.1 - 0.043 14.1 0.0 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Flu_NS2 PF00601.19 KEG15576.1 - 0.053 13.8 2.1 7.3 7.0 0.1 3.0 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) AAA_lid_6 PF17866.1 KEG15576.1 - 0.074 13.2 1.1 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA lid domain Mg_chelatase PF01078.21 KEG15576.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HOIP-UBA PF16678.5 KEG15576.1 - 0.097 12.7 1.3 5.7 6.9 0.0 3.5 3 1 0 3 3 3 0 HOIP UBA domain pair Hpr_kinase_C PF07475.12 KEG15576.1 - 0.15 11.6 0.1 5.7 6.4 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SNARE PF05739.19 KEG15577.1 - 0.00011 22.2 0.7 0.00026 20.9 0.7 1.7 1 1 0 1 1 1 1 SNARE domain CEND1 PF15677.5 KEG15577.1 - 0.042 14.4 0.1 0.054 14.0 0.1 1.3 1 1 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 KASH_CCD PF14662.6 KEG15579.1 - 2.7e-06 27.3 91.7 0.0013 18.6 25.5 5.2 1 1 3 4 4 4 2 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 KEG15579.1 - 0.0004 18.7 76.7 0.00055 18.2 76.7 1.1 1 0 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 KEG15579.1 - 0.00071 19.6 25.8 0.004 17.2 5.1 5.5 1 1 5 6 6 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KEG15579.1 - 0.0025 17.9 67.8 0.0058 16.7 5.3 10.8 4 2 8 12 12 12 4 bZIP transcription factor DUF2353 PF09789.9 KEG15579.1 - 0.0026 17.2 70.5 0.15 11.4 29.0 3.7 1 1 2 3 3 3 3 Uncharacterized coiled-coil protein (DUF2353) NRBF2 PF08961.10 KEG15579.1 - 0.0037 16.9 1.0 0.0037 16.9 1.0 6.7 1 1 6 7 7 7 2 Nuclear receptor-binding factor 2, autophagy regulator RecR PF02132.15 KEG15579.1 - 0.007 15.9 0.5 0.032 13.8 0.5 2.3 1 0 0 1 1 1 1 RecR protein BRE1 PF08647.11 KEG15579.1 - 0.013 15.6 4.5 0.013 15.6 4.5 5.3 3 2 1 5 5 5 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 KEG15579.1 - 0.018 15.2 1.2 0.018 15.2 1.2 9.6 8 2 3 12 12 11 0 Homeobox associated leucine zipper ZapB PF06005.12 KEG15579.1 - 0.021 15.3 97.8 0.046 14.2 4.8 9.8 2 2 8 10 10 9 0 Cell division protein ZapB YabA PF06156.13 KEG15579.1 - 0.061 14.0 68.2 0.12 13.0 2.9 8.0 2 2 6 8 8 8 0 Initiation control protein YabA Nop10p PF04135.12 KEG15579.1 - 0.081 13.0 0.8 0.19 11.8 0.8 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family GAS PF13851.6 KEG15579.1 - 0.23 10.8 79.8 0.06 12.7 5.5 5.3 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KEG15579.1 - 0.29 11.3 99.0 0.14 12.3 23.9 5.4 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KEG15579.1 - 1.5 8.9 42.4 2.6 8.1 0.5 5.9 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KEG15579.1 - 2.2 8.8 94.9 4.3 7.9 7.3 6.5 1 1 5 6 6 6 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KEG15579.1 - 2.7 8.5 43.4 0.53 10.7 1.0 9.5 5 3 6 12 12 12 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 KEG15579.1 - 3.6 5.0 77.4 0.012 13.2 30.1 2.7 1 1 1 2 2 1 0 Protein of unknown function (DUF3584) Filament PF00038.21 KEG15579.1 - 4.9 6.6 82.6 0.1 12.2 21.9 4.1 1 1 2 3 3 3 0 Intermediate filament protein Cep57_CLD_2 PF14197.6 KEG15580.1 - 0.039 14.0 12.4 1 9.5 7.1 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 BRI3BP PF14965.6 KEG15580.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DMPK_coil PF08826.10 KEG15580.1 - 0.15 12.2 9.7 0.51 10.5 2.5 2.8 2 1 0 2 2 2 0 DMPK coiled coil domain like UPF0184 PF03670.13 KEG15580.1 - 0.24 11.8 3.4 0.25 11.8 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Shugoshin_N PF07558.11 KEG15580.1 - 0.33 10.9 2.3 16 5.5 0.2 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 KEG15580.1 - 2.7 8.5 12.5 0.42 11.1 8.0 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region HALZ PF02183.18 KEG15580.1 - 2.9 8.2 12.3 7.7 6.8 0.4 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper zinc_ribbon_2 PF13240.6 KEG15580.1 - 5.7 6.8 8.4 7.2 6.5 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain bZIP_1 PF00170.21 KEG15580.1 - 6.4 7.0 9.2 18 5.5 0.2 2.8 3 1 0 3 3 3 0 bZIP transcription factor HEAT_EZ PF13513.6 KEG15581.1 - 4.3e-09 36.7 26.1 0.0025 18.3 1.1 9.3 7 2 3 10 10 9 4 HEAT-like repeat HEAT_2 PF13646.6 KEG15581.1 - 6.1e-08 32.9 22.1 0.0027 18.0 0.0 9.0 6 4 5 11 11 11 2 HEAT repeats Cnd1 PF12717.7 KEG15581.1 - 8.8e-07 29.1 0.3 0.048 13.7 0.0 3.7 3 1 0 3 3 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEG15581.1 - 1.1e-06 28.4 22.1 0.14 12.5 0.1 10.5 11 0 0 11 11 11 2 HEAT repeat IBN_N PF03810.19 KEG15581.1 - 4.5e-06 26.5 0.0 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DRIM PF07539.12 KEG15581.1 - 5.7e-05 21.6 6.0 0.0076 14.6 1.1 4.2 5 0 0 5 5 5 2 Down-regulated in metastasis Arm PF00514.23 KEG15581.1 - 8.8e-05 22.4 4.6 7.8 6.7 0.0 7.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KEG15581.1 - 0.00092 18.8 0.0 13 5.3 0.0 5.0 3 2 1 4 4 4 0 CLASP N terminal Gcn1_N PF12074.8 KEG15581.1 - 0.0017 17.7 0.2 1.9 7.7 0.0 2.8 3 0 0 3 3 3 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Vac14_Fab1_bd PF12755.7 KEG15581.1 - 0.0066 17.0 0.0 1.5 9.5 0.0 4.4 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KEG15581.1 - 0.016 15.1 0.0 27 4.6 0.0 4.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) NUC173 PF08161.12 KEG15581.1 - 0.018 14.7 0.3 3.2 7.3 0.0 4.3 5 1 1 6 6 6 0 NUC173 domain Importin_rep_4 PF18808.1 KEG15581.1 - 0.034 14.4 11.5 0.92 9.8 0.1 5.4 6 1 0 6 6 5 0 Importin repeat Tti2 PF10521.9 KEG15581.1 - 0.064 12.8 0.1 9.4 5.7 0.0 3.6 3 0 0 3 3 3 0 Tti2 family MMS19_C PF12460.8 KEG15581.1 - 1.8 7.6 6.1 1.6 7.7 0.5 3.4 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Cornichon PF03311.14 KEG15582.1 - 3.3e-07 30.6 0.9 3.9e-07 30.4 0.9 1.2 1 0 0 1 1 1 1 Cornichon protein DUF898 PF05987.13 KEG15582.1 - 0.051 12.6 5.2 0.052 12.6 5.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Cornichon PF03311.14 KEG15583.1 - 1.2e-06 28.9 1.4 1.2e-06 28.9 1.4 1.8 1 1 1 2 2 2 1 Cornichon protein TraG_N PF07916.11 KEG15583.1 - 0.011 14.7 1.1 0.012 14.5 1.1 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF4191 PF13829.6 KEG15583.1 - 0.039 13.3 0.3 0.047 13.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) ANAPC4_WD40 PF12894.7 KEG15584.1 - 0.00096 19.4 0.0 0.39 11.0 0.0 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEG15584.1 - 0.0064 17.3 10.3 0.064 14.1 0.0 4.4 5 2 0 5 5 5 2 WD domain, G-beta repeat SHQ1 PF04925.15 KEG15585.1 - 7.8e-37 126.5 0.0 1.6e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 SHQ1 protein TPR_2 PF07719.17 KEG15586.1 - 6.7e-08 32.1 0.9 0.016 15.3 0.0 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEG15586.1 - 7e-07 28.8 1.4 0.0055 16.5 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEG15586.1 - 3.5e-06 27.1 1.8 0.0058 16.8 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEG15586.1 - 5.7e-06 26.5 0.8 0.0009 19.5 0.3 3.1 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEG15586.1 - 6e-05 22.9 0.1 0.46 10.8 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 KEG15586.1 - 0.00021 21.4 0.1 0.00043 20.4 0.1 1.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 KEG15586.1 - 0.0015 18.4 0.8 0.032 14.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEG15586.1 - 0.0025 17.5 0.1 0.033 13.9 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 KEG15586.1 - 0.01 16.6 0.3 0.35 11.8 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEG15586.1 - 0.015 15.1 0.5 0.2 11.6 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KEG15586.1 - 0.017 14.5 1.0 0.13 11.6 0.3 2.0 1 1 1 2 2 2 0 MalT-like TPR region TRAPPC9-Trs120 PF08626.11 KEG15586.1 - 0.026 11.9 0.1 0.032 11.6 0.1 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_4 PF07721.14 KEG15586.1 - 0.56 11.0 5.6 2.1 9.2 0.0 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEG15586.1 - 1.2 9.9 4.7 39 5.2 0.1 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat ATG27 PF09451.10 KEG15587.1 - 1.2e-14 54.8 0.1 8.8e-14 52.0 0.1 1.9 1 1 1 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KEG15587.1 - 5.1e-08 32.3 0.3 1.8e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CKS PF01111.19 KEG15588.1 - 1.8e-35 121.0 2.6 2.4e-35 120.6 2.6 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.10 KEG15588.1 - 0.046 13.5 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Enolase_N PF03952.16 KEG15590.1 - 1.8e-08 34.7 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 KEG15590.1 - 2.1e-05 24.0 0.0 3.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain FmdE PF02663.14 KEG15590.1 - 0.15 12.1 0.4 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon F420_ligase PF01996.16 KEG15590.1 - 0.2 11.0 0.2 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase TMEM18 PF14770.6 KEG15592.1 - 9.8e-30 103.0 4.9 1.2e-29 102.7 4.9 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 SHR3_chaperone PF08229.11 KEG15592.1 - 0.075 12.0 0.9 0.32 9.9 0.2 2.0 2 0 0 2 2 2 0 ER membrane protein SH3 DUF5047 PF16466.5 KEG15592.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5047) Jnk-SapK_ap_N PF09744.9 KEG15595.1 - 0.11 12.7 4.4 0.26 11.5 4.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ECH_2 PF16113.5 KEG15596.1 - 2e-113 379.3 0.0 2.3e-113 379.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KEG15596.1 - 1.3e-26 93.5 0.0 1.7e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEG15597.1 - 2.5e-115 385.6 0.0 1.4e-105 353.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KEG15597.1 - 1.8e-26 93.0 0.0 3.1e-25 88.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase HTH_32 PF13565.6 KEG15597.1 - 0.0057 17.2 0.9 1.6 9.4 0.1 3.2 2 1 1 3 3 3 2 Homeodomain-like domain MAGP PF05507.11 KEG15597.1 - 0.06 13.7 0.2 0.61 10.5 0.0 2.3 2 1 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) DUF460 PF04312.13 KEG15598.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Baculo_gp64 PF03273.13 KEG15599.1 - 0.044 12.6 0.3 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family ANAPC_CDC26 PF10471.9 KEG15599.1 - 5.5 7.9 17.1 0.57 11.0 10.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 PH_6 PF15406.6 KEG15600.1 - 0.0074 16.6 0.4 0.016 15.5 0.1 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KEG15600.1 - 0.029 14.9 0.1 0.042 14.3 0.1 1.5 1 1 0 1 1 1 0 PH domain zf-CCCH PF00642.24 KEG15602.1 - 1.4e-06 28.0 4.1 2.3e-06 27.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEG15602.1 - 2.4e-05 24.0 4.7 2.4e-05 24.0 4.7 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEG15602.1 - 0.0028 17.7 1.2 0.0028 17.7 1.2 2.3 2 1 0 2 2 2 1 Zinc finger domain Torus PF16131.5 KEG15602.1 - 0.017 15.8 0.2 0.021 15.5 0.2 1.2 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KEG15602.1 - 0.04 14.4 1.8 0.04 14.4 1.8 2.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger GYF_2 PF14237.6 KEG15603.1 - 2.9e-15 55.8 0.7 6.3e-15 54.7 0.7 1.6 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 KEG15603.1 - 4.3e-11 42.8 0.1 9.3e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain UPF0004 PF00919.20 KEG15604.1 - 2.9e-20 72.1 0.0 6.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KEG15604.1 - 2e-19 70.6 0.1 7.5e-19 68.7 0.2 1.9 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 KEG15604.1 - 3.9e-05 23.5 0.1 8.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 TRAM domain DUF155 PF02582.14 KEG15605.1 - 1e-13 51.8 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mito_carr PF00153.27 KEG15606.1 - 2.8e-05 23.9 8.7 0.76 9.7 0.2 4.9 3 2 0 4 4 4 4 Mitochondrial carrier protein BCD PF15461.6 KEG15606.1 - 0.0052 16.3 0.3 0.018 14.5 0.3 2.0 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Tim17 PF02466.19 KEG15606.1 - 0.041 14.2 0.2 0.39 11.1 0.1 2.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family zf-C2H2_2 PF12756.7 KEG15607.1 - 2.6e-26 91.9 9.4 4.1e-19 68.8 0.0 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEG15607.1 - 3.1e-12 46.4 9.2 4.2e-07 30.1 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KEG15607.1 - 1.9e-07 30.9 8.8 0.0075 16.2 0.8 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KEG15607.1 - 6e-07 29.7 9.2 8.6e-05 22.8 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KEG15607.1 - 2.2e-06 28.0 15.8 0.0016 19.1 0.5 4.6 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KEG15607.1 - 4.6e-05 23.7 18.0 0.015 15.7 0.7 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 KEG15607.1 - 0.0021 17.6 3.9 0.051 13.2 0.0 3.8 4 0 0 4 4 4 1 Zinc-finger C2H2-type zf-BED PF02892.15 KEG15607.1 - 0.013 15.5 3.9 2.5 8.2 0.1 3.8 4 0 0 4 4 4 0 BED zinc finger zf-C2H2_9 PF16293.5 KEG15607.1 - 0.16 11.8 3.2 17 5.3 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_Hakai PF18408.1 KEG15607.1 - 0.25 11.1 2.4 0.27 11.0 0.7 1.9 2 0 0 2 2 1 0 C2H2 Hakai zinc finger domain DUF1993 PF09351.10 KEG15607.1 - 0.47 10.6 2.6 0.55 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) zf_C2H2_ZHX PF18387.1 KEG15607.1 - 0.93 9.2 10.6 3.3 7.4 0.1 4.3 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain AKAP95 PF04988.12 KEG15607.1 - 1 9.6 7.7 7.3 6.8 1.5 3.2 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Zn-ribbon_8 PF09723.10 KEG15607.1 - 1.3 9.2 5.4 36 4.6 0.1 3.8 4 0 0 4 4 4 0 Zinc ribbon domain TFIIS_C PF01096.18 KEG15607.1 - 3.1 7.7 6.3 0.34 10.8 0.3 2.5 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) PhoLip_ATPase_C PF16212.5 KEG15608.1 - 3.1e-43 148.3 20.8 3.1e-43 148.3 20.8 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEG15608.1 - 1.4e-17 63.1 2.7 3.8e-17 61.7 2.7 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEG15608.1 - 1.1e-09 38.9 0.3 0.0083 16.4 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEG15608.1 - 2.6e-08 33.8 0.0 8.4e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KEG15608.1 - 0.001 18.7 0.2 0.0065 16.0 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEG15608.1 - 0.0039 17.0 0.1 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 KEG15609.1 - 1.8e-21 75.8 23.6 0.00028 21.2 1.3 6.4 4 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEG15609.1 - 6.6e-12 45.0 22.8 8.6e-06 25.4 0.4 5.0 3 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KEG15609.1 - 4e-09 36.2 8.8 3.5e-06 26.6 0.2 4.1 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 KEG15609.1 - 0.00017 21.4 6.1 3.8 7.8 0.2 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 KEG15609.1 - 0.08 13.5 7.7 1.1e+02 4.0 0.0 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat DUF2433 PF10360.9 KEG15609.1 - 0.16 12.1 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) TTL PF03133.15 KEG15610.1 - 1.1e-51 175.8 0.0 1.2e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KEG15610.1 - 9.2e-10 38.2 0.0 0.0012 18.1 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KEG15610.1 - 2.9e-07 30.0 0.0 0.0068 15.7 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 KEG15610.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus PhyH PF05721.13 KEG15611.1 - 2e-23 83.8 0.0 2.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 KEG15611.1 - 0.016 15.0 0.0 1.1 9.0 0.0 2.3 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Laminin_G_3 PF13385.6 KEG15611.1 - 0.072 13.2 0.3 4.7 7.4 0.0 2.2 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily DEAD PF00270.29 KEG15612.1 - 2.5e-16 60.0 0.0 8.2e-16 58.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEG15612.1 - 3.6e-13 49.8 0.1 1.2e-12 48.2 0.1 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Prok-JAB PF14464.6 KEG15613.1 - 0.56 10.0 2.3 3.8 7.3 0.1 2.9 2 1 1 3 3 3 0 Prokaryotic homologs of the JAB domain Exonuc_VII_L PF02601.15 KEG15613.1 - 8.5 5.9 10.9 17 4.9 10.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PUA_3 PF17785.1 KEG15614.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 PUA-like domain SET PF00856.28 KEG15615.1 - 2.3e-10 41.1 0.0 5.6e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 SET domain SUIM_assoc PF16619.5 KEG15616.1 - 0.00051 20.1 0.0 0.1 12.6 0.0 3.2 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TMF_TATA_bd PF12325.8 KEG15616.1 - 0.0052 17.0 2.6 0.0052 17.0 2.6 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Dzip-like_N PF13815.6 KEG15616.1 - 0.0065 16.4 3.9 0.0065 16.4 3.9 2.7 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2_4 PF13894.6 KEG15616.1 - 0.0087 16.8 2.7 0.032 15.0 2.7 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KEG15616.1 - 0.017 15.5 4.2 0.045 14.2 4.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3450 PF11932.8 KEG15616.1 - 0.068 12.5 12.1 0.57 9.4 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-C2H2_11 PF16622.5 KEG15616.1 - 0.2 11.4 6.8 0.68 9.8 6.8 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type DUF1664 PF07889.12 KEG15616.1 - 0.31 11.1 3.1 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KEG15616.1 - 0.35 10.7 12.9 0.074 12.8 1.4 2.5 2 0 0 2 2 2 0 Septum formation initiator Holin_BhlA PF10960.8 KEG15616.1 - 1.9 8.5 7.7 6.7 6.8 0.5 2.6 2 0 0 2 2 2 0 BhlA holin family DUF3509 PF12021.8 KEG15616.1 - 2.3 8.0 8.7 1.1 9.1 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) SlyX PF04102.12 KEG15616.1 - 5.6 7.7 14.1 22 5.8 0.9 2.9 2 0 0 2 2 2 0 SlyX Pyridoxal_deC PF00282.19 KEG15617.1 - 8.2e-19 67.6 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KEG15617.1 - 0.00061 18.8 0.0 0.0023 16.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEG15617.1 - 0.0044 16.4 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-B_box PF00643.24 KEG15618.1 - 5.2e-09 36.1 29.4 8.3e-07 29.1 7.2 4.0 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 KEG15618.1 - 1.6e-07 31.0 8.1 1.6e-07 31.0 8.1 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEG15618.1 - 3.2e-07 30.4 9.3 3.2e-07 30.4 9.3 3.6 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KEG15618.1 - 9.4e-07 28.6 7.8 9.4e-07 28.6 7.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEG15618.1 - 3.2e-05 23.8 5.5 3.2e-05 23.8 5.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEG15618.1 - 0.00021 21.6 7.5 0.00021 21.6 7.5 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KEG15618.1 - 0.00039 20.3 8.2 0.00039 20.3 8.2 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C2H2_jaz PF12171.8 KEG15618.1 - 8 6.9 10.4 3.7 7.9 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Arf PF00025.21 KEG15619.1 - 5.7e-49 165.9 0.0 6.6e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEG15619.1 - 4.2e-14 52.4 0.0 5.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KEG15619.1 - 2.8e-11 43.2 0.0 4.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KEG15619.1 - 1.9e-10 40.8 0.0 2.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KEG15619.1 - 2e-09 37.3 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEG15619.1 - 2.3e-09 37.5 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KEG15619.1 - 2.7e-05 23.6 0.0 6.5e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KEG15619.1 - 5.7e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KEG15619.1 - 0.0034 16.9 0.1 0.11 12.1 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KEG15619.1 - 0.02 14.5 0.0 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 KEG15619.1 - 0.027 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_16 PF13191.6 KEG15619.1 - 0.031 14.7 0.0 0.042 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEG15619.1 - 0.032 14.5 0.0 0.071 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEG15619.1 - 0.036 14.0 0.0 7.5 6.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase CdhD PF03599.16 KEG15619.1 - 0.041 12.6 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit TniB PF05621.11 KEG15619.1 - 0.042 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MeaB PF03308.16 KEG15619.1 - 0.06 12.3 0.0 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 KEG15619.1 - 0.092 12.0 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KEG15619.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KEG15619.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4407 PF14362.6 KEG15620.1 - 1e-05 25.1 8.9 1e-05 25.1 8.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 KEG15620.1 - 0.024 15.2 25.3 0.12 13.0 10.3 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region Herpes_UL6 PF01763.16 KEG15620.1 - 0.071 11.6 3.8 0.1 11.1 3.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like Mito_fiss_reg PF05308.11 KEG15621.1 - 0.028 14.5 0.9 0.057 13.5 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KEG15621.1 - 0.27 10.7 5.8 0.48 9.8 5.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KEG15621.1 - 5.8 7.0 10.7 1.2 9.2 6.7 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Vps26 PF03643.15 KEG15622.1 - 1.5e-21 76.6 0.0 1.2e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KEG15622.1 - 1e-05 25.7 0.6 0.00011 22.3 0.3 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CLP1_P PF16575.5 KEG15624.1 - 2e-47 161.4 0.0 2.5e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KEG15624.1 - 0.00019 21.6 0.0 0.00047 20.3 0.0 1.6 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KEG15624.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 KEG15624.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEG15624.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KEG15624.1 - 0.049 14.2 0.0 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEG15624.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 KEG15624.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 KEG15624.1 - 0.083 12.9 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KEG15624.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KEG15624.1 - 0.12 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KEG15624.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family PTH2 PF01981.16 KEG15625.1 - 3.6e-23 82.1 0.2 1.2e-22 80.4 0.0 1.8 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.11 KEG15625.1 - 0.011 15.4 7.7 0.014 15.1 7.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NPR3 PF03666.13 KEG15625.1 - 0.011 14.5 0.3 0.013 14.3 0.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BT1 PF03092.16 KEG15625.1 - 0.035 12.3 0.2 0.042 12.1 0.2 1.1 1 0 0 1 1 1 0 BT1 family HemY_N PF07219.13 KEG15625.1 - 0.042 14.1 0.6 0.073 13.3 0.6 1.4 1 1 0 1 1 1 0 HemY protein N-terminus Pox_Ag35 PF03286.14 KEG15625.1 - 0.075 12.8 10.0 0.15 11.9 10.0 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 KEG15625.1 - 0.087 12.5 11.0 0.12 12.1 11.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.22 KEG15625.1 - 0.092 12.0 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 KEG15625.1 - 0.12 12.4 0.5 0.14 12.1 0.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LapA_dom PF06305.11 KEG15625.1 - 0.14 12.0 3.3 0.76 9.6 3.3 2.1 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Presenilin PF01080.17 KEG15625.1 - 0.2 10.4 2.4 0.23 10.2 2.4 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 KEG15625.1 - 0.4 8.5 1.1 0.49 8.3 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 KEG15625.1 - 0.74 9.2 10.4 0.94 8.8 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 KEG15625.1 - 1.2 9.4 13.3 1.6 8.9 13.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.16 KEG15625.1 - 3 7.0 5.6 4.1 6.5 5.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KEG15625.1 - 5.1 5.1 17.4 6.3 4.8 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi ANAPC3 PF12895.7 KEG15627.1 - 0.00023 21.3 0.1 0.00057 20.1 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEG15627.1 - 0.00083 19.5 2.7 0.0035 17.5 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEG15627.1 - 0.011 15.8 3.4 0.49 10.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEG15627.1 - 0.017 15.6 2.2 0.29 11.7 2.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEG15627.1 - 7.3 7.3 10.7 6.7 7.4 5.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 KEG15628.1 - 1.6e-11 44.2 0.0 3.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HSP70 PF00012.20 KEG15629.1 - 2e-263 875.0 6.5 2.5e-263 874.7 6.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEG15629.1 - 4.5e-14 52.0 2.3 3.4e-13 49.1 0.3 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 KEG15629.1 - 0.00038 20.8 3.6 6.3 7.3 0.2 4.1 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KEG15629.1 - 0.0088 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Dynamin_M PF01031.20 KEG15629.1 - 0.033 13.4 2.7 0.042 13.1 0.1 2.2 2 0 0 2 2 2 0 Dynamin central region Methyltransf_25 PF13649.6 KEG15629.1 - 0.077 13.7 0.5 17 6.2 0.0 3.0 2 0 0 2 2 2 0 Methyltransferase domain TSNAXIP1_N PF15739.5 KEG15631.1 - 3.8e-10 40.1 0.8 3.8e-10 40.1 0.8 4.1 3 1 0 4 4 4 1 Translin-associated factor X-interacting N-terminus DUF3090 PF11290.8 KEG15631.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3090) Allexi_40kDa PF05549.11 KEG15631.1 - 2 7.9 6.2 0.76 9.2 1.0 2.8 2 1 0 3 3 3 0 Allexivirus 40kDa protein CSN5_C PF18323.1 KEG15631.1 - 5 8.1 6.0 1.9 9.4 1.0 2.9 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Cofilin_ADF PF00241.20 KEG15632.1 - 2.5e-08 33.8 0.0 0.00044 20.0 0.0 2.7 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pox_F12L PF03337.13 KEG15632.1 - 0.052 11.7 0.0 0.074 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein DUF4234 PF14018.6 KEG15633.1 - 0.048 13.8 0.2 0.09 12.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) JAB PF01398.21 KEG15634.1 - 6e-30 103.7 0.0 8.7e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KEG15634.1 - 5.4e-09 35.8 0.0 8.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KEG15634.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) AAA_12 PF13087.6 KEG15635.1 - 1.3e-25 90.2 0.0 3.2e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEG15635.1 - 5.7e-15 55.8 0.8 1.7e-09 37.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEG15635.1 - 2.1e-08 34.6 0.2 3.6e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEG15635.1 - 1.2e-07 31.6 0.3 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEG15635.1 - 8.4e-05 22.4 0.1 2.9 7.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KEG15635.1 - 0.0014 18.2 0.2 0.008 15.7 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KEG15635.1 - 0.0017 18.6 0.3 0.053 13.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KEG15635.1 - 0.022 14.1 0.0 0.068 12.5 0.0 1.8 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 KEG15635.1 - 0.028 13.7 0.2 0.072 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KEG15635.1 - 0.1 13.0 0.1 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 KEG15635.1 - 0.14 12.2 0.1 0.42 10.7 0.1 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KEG15635.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KEG15635.1 - 0.18 11.7 0.2 23 4.8 0.0 2.4 2 0 0 2 2 2 0 Helicase Terminase_2 PF03592.16 KEG15635.1 - 0.19 12.2 0.1 0.62 10.5 0.1 1.9 1 0 0 1 1 1 0 Terminase small subunit HALZ PF02183.18 KEG15636.1 - 0.05 13.8 5.4 1.6 9.0 1.1 4.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF5320 PF17253.2 KEG15636.1 - 5.3 8.2 10.6 0.43 11.7 2.0 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5320) PHTB1_C PF14728.6 KEG15637.1 - 1.1 8.3 8.5 0.03 13.4 1.7 1.8 2 0 0 2 2 2 0 PTHB1 C-terminus DUF1897 PF09005.10 KEG15638.1 - 0.16 11.5 0.5 0.29 10.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) FOP_dimer PF09398.10 KEG15640.1 - 0.009 16.2 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Plasmodium_Vir PF05795.11 KEG15640.1 - 0.23 10.9 4.6 0.38 10.1 4.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spc7 PF08317.11 KEG15640.1 - 3.7 6.3 19.6 3 6.6 17.3 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 KEG15640.1 - 5.5 7.3 26.8 0.38 11.1 15.5 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Bot1p PF12298.8 KEG15641.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Trimer_CC PF08954.11 KEG15641.1 - 6.1 6.5 11.3 0.1 12.2 0.5 3.0 3 0 0 3 3 3 0 Trimerisation motif DUF2204 PF09970.9 KEG15642.1 - 0.006 16.2 1.3 0.0067 16.1 1.3 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Osmo_CC PF08946.10 KEG15642.1 - 0.011 16.0 2.1 0.023 14.9 2.1 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil HR1 PF02185.16 KEG15642.1 - 0.013 15.6 2.0 0.02 15.0 2.0 1.4 1 0 0 1 1 1 0 Hr1 repeat Csm1_N PF18504.1 KEG15642.1 - 0.024 15.0 4.0 0.036 14.4 3.6 1.6 1 1 0 1 1 1 0 Csm1 N-terminal domain DUF5339 PF17274.2 KEG15642.1 - 0.05 14.5 2.2 0.081 13.8 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5339) SlyX PF04102.12 KEG15642.1 - 0.11 13.1 2.2 0.13 12.9 1.1 1.7 1 1 0 1 1 1 0 SlyX DUF668 PF05003.12 KEG15642.1 - 0.12 12.9 1.0 0.17 12.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Fib_alpha PF08702.10 KEG15642.1 - 0.18 12.0 4.9 0.23 11.6 4.8 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PRP1_N PF06424.12 KEG15642.1 - 1.2 9.6 9.3 1.4 9.4 9.3 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3287 PF11690.8 KEG15642.1 - 1.2 8.8 9.4 1.8 8.3 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) GTP_EFTU PF00009.27 KEG15643.1 - 1.8e-43 148.3 0.0 2.9e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KEG15643.1 - 2.7e-32 111.1 2.7 5.6e-32 110.1 2.7 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KEG15643.1 - 5e-17 61.7 0.0 1.2e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KEG15643.1 - 0.00035 20.6 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KEG15643.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KEG15643.1 - 0.042 13.3 0.0 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4704 PF15787.5 KEG15644.1 - 0.027 13.7 0.4 0.065 12.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) SNAP PF14938.6 KEG15645.1 - 7.7e-13 48.5 8.1 2.1e-05 24.1 7.7 2.7 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KEG15645.1 - 0.063 13.3 0.2 57 4.1 0.0 4.3 4 2 0 4 4 4 0 Tetratricopeptide repeat NSF PF02071.20 KEG15645.1 - 1.9 9.6 7.3 92 4.6 0.4 4.5 3 1 1 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat JIP_LZII PF16471.5 KEG15646.1 - 0.071 13.3 7.1 0.12 12.6 2.1 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Fungal_TACC PF12709.7 KEG15646.1 - 1.8 9.1 4.9 3 8.4 0.5 2.8 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Macoilin PF09726.9 KEG15648.1 - 5.1 5.5 11.1 15 3.9 11.1 1.8 1 0 0 1 1 1 0 Macoilin family TMEM174 PF15029.6 KEG15649.1 - 3.2 7.4 4.1 1.7 8.3 0.1 2.4 2 1 0 2 2 2 0 Transmembrane protein 174 HEAT_2 PF13646.6 KEG15650.1 - 9.9e-11 41.9 0.7 0.09 13.2 0.0 5.7 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KEG15650.1 - 1.8e-09 37.9 12.0 0.004 17.6 0.0 6.8 6 2 3 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KEG15650.1 - 1.2e-07 32.3 1.8 0.006 17.2 0.0 5.2 3 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KEG15650.1 - 1.7e-07 31.1 0.6 0.00012 22.0 0.0 4.2 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT PF02985.22 KEG15650.1 - 1.2e-05 25.1 10.8 2.4 8.6 0.0 8.7 11 0 0 11 11 11 2 HEAT repeat CLASP_N PF12348.8 KEG15650.1 - 0.00015 21.4 0.3 0.29 10.7 0.3 3.2 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.23 KEG15650.1 - 0.00025 21.0 9.7 0.87 9.7 0.1 6.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KEG15650.1 - 0.057 13.3 1.0 6.3 6.7 0.1 3.2 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Catalase-rel PF06628.12 KEG15650.1 - 0.067 13.4 1.2 0.29 11.4 0.1 2.7 4 0 0 4 4 4 0 Catalase-related immune-responsive MMS19_C PF12460.8 KEG15650.1 - 3 6.8 9.0 4.1 6.4 0.0 4.2 4 2 1 5 5 5 0 RNAPII transcription regulator C-terminal Enolase_C PF00113.22 KEG15651.1 - 2.8e-135 450.3 0.6 5.2e-89 298.4 0.0 2.1 1 1 1 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KEG15651.1 - 4.8e-57 191.8 0.0 9e-57 190.9 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KEG15651.1 - 6.8e-08 32.3 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KEG15651.1 - 0.002 17.3 0.4 0.0039 16.4 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Ion_trans PF00520.31 KEG15652.1 - 5.5e-125 415.5 103.0 3.1e-38 131.4 16.1 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KEG15652.1 - 8.3e-06 25.5 0.0 2.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated ANTH PF07651.16 KEG15653.1 - 0.28 10.1 0.0 0.28 10.1 0.0 2.4 3 0 0 3 3 3 0 ANTH domain OmpH PF03938.14 KEG15653.1 - 6.6 7.1 10.3 4.8 7.5 7.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 KEG15654.1 - 3.6e-42 141.5 26.1 1.4e-06 28.9 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEG15654.1 - 3e-10 40.3 0.0 0.00064 20.0 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEG15654.1 - 0.00012 21.2 0.3 2.8 6.8 0.1 3.9 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEG15654.1 - 0.015 15.2 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4106 PF13388.6 KEG15655.1 - 0.13 11.5 2.3 0.24 10.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ribosomal_S25 PF03297.15 KEG15656.1 - 5.4e-36 122.8 5.7 6.2e-36 122.6 5.7 1.1 1 0 0 1 1 1 1 S25 ribosomal protein CREPT PF16566.5 KEG15659.1 - 0.025 14.8 1.7 0.025 14.8 1.7 2.2 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Hormone_3 PF00159.18 KEG15659.1 - 0.078 13.1 0.2 0.9 9.7 0.0 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide BMFP PF04380.13 KEG15659.1 - 0.18 12.3 5.1 0.19 12.2 0.2 2.8 2 1 1 3 3 3 0 Membrane fusogenic activity Ribosomal_S6 PF01250.17 KEG15660.1 - 0.00072 19.8 0.1 0.0011 19.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 TarS_C1 PF18674.1 KEG15660.1 - 0.0078 16.1 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 TarS beta-glycosyltransferase C-terminal domain 1 COG6 PF06419.11 KEG15661.1 - 6.1e-48 163.5 0.0 1.2e-38 132.8 0.0 2.9 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 RNA_pol_Rpb1_5 PF04998.17 KEG15662.1 - 5.3e-80 268.7 0.0 7.5e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEG15662.1 - 2.5e-68 229.5 0.0 4.3e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KEG15662.1 - 1.9e-54 185.2 0.0 3e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KEG15662.1 - 1.1e-31 108.9 0.0 3e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 KEG15662.1 - 1.5e-31 109.4 0.0 3.6e-31 108.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 Rpr2 PF04032.16 KEG15662.1 - 0.36 11.1 1.3 1.5 9.1 1.3 2.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain eIF-5_eIF-2B PF01873.17 KEG15663.1 - 3.1e-31 107.7 0.5 6.9e-31 106.6 0.1 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 KEG15663.1 - 0.0013 18.9 0.0 0.0057 16.8 0.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Vir_act_alpha_C PF10400.9 KEG15663.1 - 0.0017 19.0 0.4 0.013 16.1 0.1 2.2 2 0 0 2 2 2 1 Virulence activator alpha C-term zinc_ribbon_12 PF11331.8 KEG15663.1 - 0.1 12.4 3.0 0.34 10.7 3.0 1.9 1 1 0 1 1 1 0 Probable zinc-ribbon domain Ribosomal_60s PF00428.19 KEG15663.1 - 0.69 10.5 10.9 4.7 7.9 9.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA PF00004.29 KEG15664.1 - 1.4e-06 28.8 0.0 0.00012 22.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEG15664.1 - 4e-05 24.1 1.2 0.00021 21.7 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEG15664.1 - 0.00039 20.7 0.1 0.0029 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEG15664.1 - 0.0018 18.0 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KEG15664.1 - 0.0035 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 KEG15664.1 - 0.0045 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEG15664.1 - 0.0048 17.1 0.5 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEG15664.1 - 0.01 15.4 0.0 0.031 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEG15664.1 - 0.015 15.6 0.1 0.031 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEG15664.1 - 0.018 14.9 0.2 0.077 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KEG15664.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 KEG15664.1 - 0.019 15.2 0.3 0.059 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEG15664.1 - 0.025 14.5 0.0 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KEG15664.1 - 0.036 14.5 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.6 KEG15664.1 - 0.042 14.4 0.1 0.12 12.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEG15664.1 - 0.088 12.8 0.1 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KEG15664.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 KEG15664.1 - 0.15 11.5 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 KEG15664.1 - 0.17 11.6 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DS PF01916.17 KEG15665.1 - 1.2e-63 215.1 0.0 3.7e-53 180.7 0.0 2.5 2 1 0 2 2 2 2 Deoxyhypusine synthase START PF01852.19 KEG15666.1 - 3.6e-08 33.1 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 START domain PseudoU_synth_1 PF01416.20 KEG15667.1 - 1.4e-10 41.5 0.0 6.3e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 KEG15668.1 - 1.6e-16 60.4 6.7 0.0049 17.7 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KEG15668.1 - 0.00028 19.7 0.0 0.05 12.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Mon1 PF03164.14 KEG15669.1 - 1e-47 163.1 0.0 4e-47 161.2 0.0 1.6 1 1 1 2 2 2 2 Trafficking protein Mon1 Pyr_redox_2 PF07992.14 KEG15670.1 - 2.8e-16 59.6 0.0 1.8e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEG15670.1 - 4.6e-05 22.6 0.6 7.4e-05 22.0 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KEG15670.1 - 5.1e-05 23.0 0.8 0.0012 18.5 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEG15670.1 - 0.00011 22.7 0.0 0.02 15.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEG15670.1 - 0.0002 21.5 0.3 0.00077 19.7 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KEG15670.1 - 0.00047 20.4 0.1 0.05 13.9 0.0 2.8 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KEG15670.1 - 0.0015 18.2 0.1 0.003 17.2 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KEG15670.1 - 0.0028 16.4 0.1 0.0055 15.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KEG15670.1 - 0.0063 15.6 1.8 0.014 14.5 1.2 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KEG15670.1 - 0.012 15.6 0.2 0.028 14.4 0.0 1.7 2 0 0 2 2 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KEG15670.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KEG15670.1 - 0.025 13.4 0.1 0.038 12.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KEG15670.1 - 0.032 13.5 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KEG15670.1 - 0.04 14.0 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KEG15670.1 - 0.063 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KEG15670.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KEG15670.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KEG15670.1 - 0.18 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Meis_PKNOX_N PF16493.5 KEG15671.1 - 0.091 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Thymidylate_kin PF02223.17 KEG15671.1 - 0.12 12.1 0.3 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Thymidylate kinase GerA PF03323.13 KEG15673.1 - 0.25 9.7 2.8 0.59 8.5 2.8 1.6 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein IFT81_CH PF18383.1 KEG15674.1 - 3.6e-31 108.0 0.3 1.1e-30 106.4 0.0 2.0 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain zf-C2H2 PF00096.26 KEG15674.1 - 0.00022 21.5 0.9 0.00053 20.3 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type Spc7 PF08317.11 KEG15674.1 - 0.0028 16.6 9.2 0.0028 16.6 9.2 5.4 2 1 3 5 5 5 2 Spc7 kinetochore protein zf-C2H2_4 PF13894.6 KEG15674.1 - 0.0061 17.3 1.3 0.013 16.3 1.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger NEMO PF11577.8 KEG15674.1 - 0.0099 15.9 2.0 0.0099 15.9 2.0 4.0 3 2 0 3 3 3 1 NF-kappa-B essential modulator NEMO BORCS6 PF10157.9 KEG15674.1 - 0.019 15.2 1.5 0.079 13.2 1.5 2.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Seryl_tRNA_N PF02403.22 KEG15674.1 - 0.027 14.7 0.3 0.027 14.7 0.3 6.3 2 2 4 7 7 7 0 Seryl-tRNA synthetase N-terminal domain zf-Di19 PF05605.12 KEG15674.1 - 0.029 14.7 0.1 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KEG15674.1 - 0.12 12.9 0.4 1.3 9.5 0.4 3.0 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Filament PF00038.21 KEG15674.1 - 0.14 11.7 51.7 0.56 9.7 7.5 4.4 2 1 2 4 4 4 0 Intermediate filament protein Scaffolding_pro PF11418.8 KEG15674.1 - 0.54 10.8 0.0 0.54 10.8 0.0 4.4 5 1 1 6 6 6 0 Phi29 scaffolding protein HisKA_2 PF07568.12 KEG15674.1 - 1.7 8.8 7.1 35 4.6 0.2 4.3 3 0 0 3 3 3 0 Histidine kinase Fib_alpha PF08702.10 KEG15674.1 - 5.7 7.1 38.9 0.46 10.7 4.5 5.0 3 1 2 5 5 5 0 Fibrinogen alpha/beta chain family Ist1 PF03398.14 KEG15675.1 - 6.5e-44 149.8 0.1 7.8e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway CS PF04969.16 KEG15676.1 - 2e-07 31.9 0.0 3.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF1935 PF09149.10 KEG15677.1 - 7.9e-120 392.4 0.4 1.4e-29 102.5 0.0 4.0 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Trypanosoma_grayi-Tgr_V1/GCA_000691245.1_Tgr_V1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Trypanosoma_grayi-Tgr_V1/GCA_000691245.1_Tgr_V1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Trypanosoma_grayi-Tgr_V1/GCA_000691245.1_Tgr_V1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Trypanosoma_grayi-Tgr_V1/GCA_000691245.1_Tgr_V1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 09:13:54 2019 # [ok]